******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.0.5 (Release date: Mon Mar 18 20:12:19 2019 -0700) For further information on how to interpret please access http://meme-suite.org/. To get a copy of the MEME software please access http://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= less_than_1e-3_-_non-redundant_jalview_99_percent_9.txt CONTROL SEQUENCES= --none-- ALPHABET= ACDEFGHIKLMNPQRSTVWY Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ AAL35819.1 1.0000 202 OAO95598.1 1.0000 201 RVW33794.1 1.0000 260 XP_012074964.1 1.0000 257 XP_021650240.1 1.0000 249 XP_015896979.1 1.0000 246 XP_021622766.1 1.0000 237 XP_010528448.1 1.0000 180 XP_022742854.1 1.0000 253 PON90845.1 1.0000 245 XP_021691173.1 1.0000 252 XP_012442486.1 1.0000 282 OVA17828.1 1.0000 268 XP_010529822.1 1.0000 199 XP_002531564.2 1.0000 261 XP_010256878.1 1.0000 261 XP_007134047.1 1.0000 251 XP_023913884.1 1.0000 245 XP_006410959.1 1.0000 191 TKY63306.1 1.0000 262 XP_027336786.1 1.0000 253 XP_022747248.1 1.0000 249 VDD15356.1 1.0000 380 TKY66008.1 1.0000 226 XP_024189435.1 1.0000 258 TKR66562.1 1.0000 257 KFK36656.1 1.0000 197 PIA54706.1 1.0000 263 RXI02216.1 1.0000 257 TEY25303.1 1.0000 243 XP_008240727.1 1.0000 231 XP_026417177.1 1.0000 243 XP_028773013.1 1.0000 281 XP_006349495.1 1.0000 260 XP_009798034.1 1.0000 259 XP_021289458.1 1.0000 253 XP_027353450.1 1.0000 235 XP_017416333.1 1.0000 232 PKI43461.1 1.0000 241 XP_004302767.1 1.0000 256 XP_022846646.1 1.0000 245 XP_024028595.1 1.0000 236 XP_022983598.1 1.0000 253 XP_010047842.1 1.0000 243 OUZ99277.1 1.0000 229 PIN04755.1 1.0000 227 XP_011077640.1 1.0000 285 PHT70537.1 1.0000 272 XP_022145567.1 1.0000 248 PIN03316.1 1.0000 210 OMO66336.1 1.0000 249 XP_023734875.1 1.0000 210 GAY47919.1 1.0000 284 XP_024982170.1 1.0000 239 XP_027149457.1 1.0000 232 PSS34997.1 1.0000 261 XP_004137783.2 1.0000 347 RWR86109.1 1.0000 253 XP_028783417.1 1.0000 207 XP_022039957.1 1.0000 182 XP_022948410.1 1.0000 229 XP_004514391.1 1.0000 238 XP_028119329.1 1.0000 241 TKS09656.1 1.0000 261 XP_008803152.1 1.0000 339 PWA88889.1 1.0000 138 GAV76568.1 1.0000 264 XP_027176296.1 1.0000 242 XP_012832023.1 1.0000 194 XP_015960799.1 1.0000 189 XP_019162543.1 1.0000 244 XP_012850185.1 1.0000 204 XP_010937591.1 1.0000 280 XP_010037822.1 1.0000 257 XP_020553487.1 1.0000 244 XP_018841755.1 1.0000 222 XP_022143715.1 1.0000 169 RID43060.1 1.0000 196 XP_008448098.1 1.0000 201 XP_006398684.1 1.0000 202 XP_018806280.1 1.0000 245 ADE76868.1 1.0000 401 XP_019459351.1 1.0000 238 TEY72131.1 1.0000 249 XP_021744044.1 1.0000 206 XP_010678090.1 1.0000 228 OAY41326.1 1.0000 195 XP_021856950.1 1.0000 204 XP_013448883.1 1.0000 213 RAL39303.1 1.0000 211 PKI39361.1 1.0000 263 XP_023544624.1 1.0000 193 XP_021741222.1 1.0000 205 XP_020108001.1 1.0000 246 RWW70318.1 1.0000 145 KZV44349.1 1.0000 187 XP_020268040.1 1.0000 174 XP_020593816.1 1.0000 224 XP_010543288.1 1.0000 200 EFJ36024.1 1.0000 659 KFK24705.1 1.0000 174 PNX96427.1 1.0000 215 XP_010558336.1 1.0000 237 XP_014752653.1 1.0000 246 VAI07274.1 1.0000 249 OAE24336.1 1.0000 574 EEC74952.1 1.0000 265 RLN19347.1 1.0000 263 XP_021307618.1 1.0000 293 OEL29447.1 1.0000 359 XP_024401192.1 1.0000 402 PSS23773.1 1.0000 203 XP_018681881.1 1.0000 152 XP_017215985.1 1.0000 253 NP_001354359.1 1.0000 266 EPS60070.1 1.0000 179 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme less_than_1e-3_-_non-redundant_jalview_99_percent_9.txt -protein -oc . -nostatus -time 18000 -mod zoops -nmotifs 20 -minw 6 -maxw 50 -objfun classic -markov_order 0 model: mod= zoops nmotifs= 20 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values width: minw= 6 maxw= 50 nsites: minsites= 2 maxsites= 116 wnsites= 0.8 theta: spmap= pam spfuzz= 120 em: prior= megap b= 142785 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 28558 N= 116 sample: seed= 0 hsfrac= 0 searchsize= 28558 norand= no csites= 1000 Dirichlet mixture priors file: prior30.plib Letter frequencies in dataset: A 0.0469 C 0.0209 D 0.075 E 0.0995 F 0.0397 G 0.0541 H 0.0258 I 0.0401 K 0.0584 L 0.0778 M 0.0276 N 0.0555 P 0.04 Q 0.0414 R 0.0349 S 0.131 T 0.0462 V 0.0431 W 0.00896 Y 0.033 Background letter frequencies (from file dataset with add-one prior applied): A 0.0469 C 0.0209 D 0.075 E 0.0994 F 0.0397 G 0.0541 H 0.0258 I 0.0401 K 0.0584 L 0.0778 M 0.0276 N 0.0555 P 0.04 Q 0.0414 R 0.0349 S 0.131 T 0.0462 V 0.0431 W 0.00896 Y 0.033 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF SGTRKPTIDQEFEQYFSMLML MEME-1 width = 21 sites = 116 llr = 5416 E-value = 2.6e-1823 ******************************************************************************** -------------------------------------------------------------------------------- Motif SGTRKPTIDQEFEQYFSMLML MEME-1 Description -------------------------------------------------------------------------------- Simplified A :12::::::::::::::1::: pos.-specific C ::::::::::::::::::::: probability D :1::::::a:::::::::::: matrix E 11:1::::::a:a2::::::: F :::::::::::a:::a::::: G :4::::::::::::::::::: H 1:::::::::::::::::::: I :::::::a::::::::::::: K ::138::::2::::::::::: L 1::::3::::::::::::a19 M :::::::::::::::::6:91 N ::::::::::::::::::::: P 1:1:17::::::::::::::: Q 2::::::::7:::8::::::: R :::5::::::::::::::::: S 321:::::::::::::91::: T :14:::a::::::::::2::: V ::::::::::::::::::::: W ::::::::::::::::::::: Y ::::::::::::::a:::::: bits 6.8 6.1 5.4 4.8 ** * ** * Relative 4.1 ** * ** * Entropy 3.4 *********** *** (67.4 bits) 2.7 ***************** 2.0 ****************** 1.4 ******************** 0.7 ********************* 0.0 --------------------- Multilevel SGTRKPTIDQEFEQYFSMLML consensus K L K sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SGTRKPTIDQEFEQYFSMLML MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- --------------------- OAY41326.1 175 1.23e-27 VTDIVNADAQ PGTRKPTIDQEFEQYFSMLML XP_021622766.1 217 1.23e-27 GRWSVNQDAQ PGTRKPTIDQEFEQYFSMLML XP_023913884.1 225 3.59e-27 RRWNVNQDAQ SGTRKPTIDQEFEQYFSMLML XP_022742854.1 233 1.33e-26 GRWSVNQEAP QTTRKPTIDQEFEQYFSMLML XP_015896979.1 226 2.00e-26 GRWSVNQDTQ SGARKPTIDQEFEQYFSMLML XP_021650240.1 229 3.08e-26 GRWSVNQDAQ RGTRKPTIDQEFEQYFSMLML XP_008803152.1 319 3.35e-26 GQGMFMFDAR LGARKPTIDQEFEQYFSMLML XP_010528448.1 160 4.49e-26 RWTVNQDSSR QNTRKPTIDQEFEQYFSMLML RWW70318.1 125 8.85e-26 ERWSSGRDAR LGTRKPTIDKEFEQYFSMLML TKS09656.1 241 8.85e-26 EGWTVNQEAQ SGPRKPTIDQEFEQYFSMLML TKR66562.1 237 8.85e-26 GRWAVNQEAQ SGPRKPTIDQEFEQYFSMLML GAV76568.1 244 1.06e-25 GRWSANRDAQ QGTWKPTIDQEFEQYFSMLML XP_006410959.1 171 1.06e-25 RWTVNQDSTR QGTKKPTIDQEFEQYFSTLML RVW33794.1 240 1.58e-25 GRWSVNQDAQ IGTRKPTIDQEFEQYFSMLML XP_024028595.1 216 1.87e-25 GRRTVNQEDQ SGSRKPTIDQEFEQYFSMLML XP_010256878.1 241 2.22e-25 GRWSVNQEAR LGAKKPTIDQEFEQYFSMLML XP_022747248.1 229 4.03e-25 GRWSVNLEAP QTRRKPTIDQEFEQYFSMLML XP_012442486.1 262 4.03e-25 GRWSVNQEAQ QTKRKPTIDQEFEQYFSMLML XP_002531564.2 241 8.04e-25 GRWTVNQDAQ PGTIKPTIDQEFEQYFSMLML XP_027336786.1 233 9.57e-25 GRWSVNQEAQ SSTRPPTIDQEFEQYFSMLML XP_010937591.1 260 1.14e-24 GSWSTGHDAR LDARKPTIDQEFEQYFSMLML XP_021289458.1 233 1.14e-24 GRWSVNQGAS QTARKPTIDQEFEQYFSTLML TEY25303.1 223 1.35e-24 GRWSVNQDSQ EGTRKPTIDQEFEQYFSALML XP_021691173.1 207 1.86e-24 GKWSVNQDAQ PGTXKPTIDQEFEQYFSMLML QQRILLYKPL XP_022846646.1 225 2.57e-24 WTVNQDADTQ PGTKKLTIDKEFEQYFSMLML XP_007134047.1 231 2.57e-24 GRWDVNQEAQ SGTKAPTIDQEFEQYFSMLML OVA17828.1 248 2.57e-24 GRWNINQDAR VDTRKPTIDQEFEQYFSMLMM PKI43461.1 221 3.00e-24 GRWIVEQEGQ ATTRKPTIDKEFEQYFSMLML VDD15356.1 360 3.00e-24 RWTVDQDSTQ DGTKKPTIDQEFEQYFSTLML XP_027176296.1 222 4.15e-24 ERWTLNQDTQ QGAKKLTIDKEFEQYFSMLML PIA54706.1 243 4.15e-24 GRWNINKDAE AGMRKPTIDQEFEQYFSMLML PON90845.1 225 4.15e-24 GRWSVNQEAQ SDSRKPTIDQEFEQYFSMLML XP_010529822.1 179 4.83e-24 RWAVNRDSSL QNTMKPTIDQEFEQYFSMLML XP_010047842.1 223 5.65e-24 GRWIVNREAQ HSTRRPTIDQEFEQYFSMLML RWR86109.1 233 6.57e-24 GRWSVGPDAR LSARKPTIDQEFEQYFSTLML XP_026417177.1 223 1.03e-23 GRWDVDPDSR VDSRKPTIDQEFEQYFSMLML AAL35819.1 182 1.03e-23 WTVNQDDSTL HETKKPTIDQEFEQYFSTLML XP_027149457.1 212 1.19e-23 GRWTLNQDTQ QSTKKLTIDKEFEQYFSMLML XP_012074964.1 237 1.38e-23 GRWNVNQDAQ PVAKKPTIDQEFEQYFSMLML GAY47919.1 264 1.60e-23 GRWSHNQETQ SGKRKPTIDQEFEQYFSSLML PWA88889.1 118 1.83e-23 GRWDIIQDTE QGTEKLTIDKEFEQYFSMLML XP_022039957.1 162 1.83e-23 NQDAAAAAAE QGTEKLTIDKEFEQYFSMLML XP_023734875.1 190 1.83e-23 GRWNVNQDIQ QGTEKLTIDKEFEQYFSMLML PIN04755.1 207 1.83e-23 GRWSVNQDTQ QGTEKLTIDKEFEQYFSMLML XP_022983598.1 233 2.12e-23 GRWTVNNEDQ SSARAPTIDQEFEQYFSMLML XP_015960799.1 169 2.45e-23 GRRNVNREAQ SSTRPPTIDQEFEEYFSMLML XP_009798034.1 239 2.45e-23 GRWPVNQDPE PGPKKLTIDKEFEQYFSMLML XP_028773013.1 261 2.45e-23 GRWEVNQEAQ SSTRPPTIDQEFEEYFSMLML XP_004137783.2 327 2.80e-23 GRWAINHEAQ SRARAPTIDQEFEQYFSMLML TKY63306.1 242 3.22e-23 GRWNVNQEAQ SSTTPPTIDQEFEQYFSMLML OUZ99277.1 209 3.71e-23 GRWSIKQNTR LGARKPTIDQEFEKYFSMLML XP_021856950.1 184 9.47e-23 ERWTLNPEAQ VGRQKPTIDQEFEQYFSTLML XP_021741222.1 185 1.40e-22 DRWIADGEGD MGRQKPTIDQEFEQYFSTLML XP_020108001.1 226 1.59e-22 GQWSLGQEAR LGAQKLTIDQEFEQYFSTLML XP_021744044.1 186 1.59e-22 DRWTVDREAH RGRQKPTIDQEFEQYFSTLML XP_024982170.1 219 2.63e-22 GRWNVNQDTE QGTEKMTIDKEFEQYFSMLML XP_020268040.1 154 2.98e-22 GKCSIEQDAR LGTSKPTIDQEFEQYFSALML PIN03316.1 190 2.98e-22 GRWPVDQDAQ QESKKLTIDKEFEQYFSMLML RLN19347.1 243 3.36e-22 QILPAGQTGY QGEKKLTIDQEFEQYFSNLML OAO95598.1 181 3.36e-22 RWSVSNQDSK EATTKPTIDQEFEQYFSTLMM XP_008240727.1 211 3.81e-22 VNQDNSDVQS ASNRKPTIDQEFEQYFSTLML XP_020553487.1 224 4.29e-22 GRWSVTHDTQ PATRKLTIDKEFEQYFSSLML XP_004302767.1 236 4.84e-22 RWSVNQEAQS GSSRKPTIDQEFEQYFSSLML XP_017416333.1 212 4.84e-22 GRWNVNQEAQ SNSRPPTIDQEFEEYFSMLML XP_027353450.1 215 4.84e-22 GRWEVNQEAQ SNSRPPTIDQEFEEYFSMLML RXI02216.1 237 4.84e-22 WSVNQEGQSA GSSRKPTIDQEFEQYFSSLML XP_024189435.1 238 4.84e-22 RWSVNQEAQS GSSRKPTIDQEFEQYFSSLML XP_004514391.1 218 5.47e-22 GRWDVNQEAQ SSTRPPTIDQEFEEYFSALML OEL29447.1 339 7.82e-22 QILPTGQTGY HGEKKLTIDQEFEQYFSNLML RID43060.1 176 7.82e-22 RWSVSNQESE EATKKPTIDQEFEEYFSTLMM XP_019162543.1 224 7.82e-22 GRWEVGQDTQ EGAKKLTIDKEFEQYFGMLML XP_028783417.1 187 7.82e-22 GKWNVNQEAQ SNARPPTIDEEFEQYFSMLML XP_022145567.1 228 7.82e-22 GRWGVNHEAQ SRAMTPTIDQEFEQYFSMLML XP_010037822.1 237 8.79e-22 GRWNTNHDTL HRTRKPTIDQEFEDYFSTLMM TKY66008.1 206 8.79e-22 GRWNVNQEAQ SSSKPPTIDQEFEEYFSMLML XP_006349495.1 240 1.57e-21 GRWTVNQDSQ PSSTKLTIDKEFEQYFSMLML XP_010678090.1 208 1.97e-21 DRWNVDQEAQ MGRRKETIDQEFEQYFSTLML XP_019459351.1 218 2.20e-21 GQWNVDKEAQ SSTRPPTIDLEFEQYFSTLML OMO66336.1 229 2.46e-21 GRWSVNQEAP KTTRRPTIDQEFEQYFATLML ADE76868.1 381 2.75e-21 GRVTQNKDAR TGSRPPTIDKDFEQYFSMLML XP_006398684.1 182 3.84e-21 KWSVSNQDSE EATTKPTIDQEFEEYFSTLMM XP_021307618.1 273 4.28e-21 QILPTGQTGY HSEKKLTIDQEFEQYFSNLML XP_018841755.1 202 4.28e-21 ERWTVGQDAQ PGTRKQTIDQEFEQFFSNLML XP_012832023.1 174 4.28e-21 GRWPVHQDNQ EDTKKLTIDKEFEEYFSMLMM XP_011077640.1 265 4.28e-21 GRWSVNQDTQ QEGKKLTIDKEFEQYFAMLML PKI39361.1 243 4.78e-21 GQLSMNEETQ SAPRKPTIDQEFEEYFSSLMM PHT70537.1 252 4.78e-21 GRWTVNQDSQ PSSTKLTIDKEFEQYFSMLMM NP_001354359.1 246 5.32e-21 QILPTGQTGY HGEKKLTIDQEFEQYFANLML XP_010543288.1 180 5.93e-21 LSSPRLSDSS QDTREPTIDQEFEQYFSSLMM XP_020593816.1 204 7.34e-21 RWNLGKGAPL VGARKLTIDQEFEQYFSSLLL RAL39303.1 190 9.09e-21 RWKVGQQESE EGKKKLTIDKEFEQYFGTLML Q XP_014752653.1 226 1.01e-20 ILPAGKTGCH GEKKKLTIDQEFEQYFSKLML XP_012850185.1 184 1.01e-20 RWSVNNQGNE QESKKLTIDKEFEEYFSMLMM KFK36656.1 177 1.25e-20 RWTVNQDSIE NDIKKPTIDQEFEEYFSTLML PSS34997.1 241 2.31e-20 GRWSVNQENQ STSKNLTIDKEFEQYFSMLML XP_018681881.1 132 3.83e-20 ENKNSLADGP LGARKPTIGKESEQYFSMLML TEY72131.1 229 4.68e-20 VDQGARAMQE EGKKKLTIDNEFEQFFSMLML XP_028119329.1 221 6.93e-20 GRWSVNQETP LSPKKLTIDKEFEQYFSMLTL XP_022143715.1 149 1.81e-19 WNVDPPSEAE SKTLKPTIDQEFEQYFSVLLL PNX96427.1 195 1.99e-19 ILILNQTEAD SSIRPPTIDEEFEEYFSALML PSS23773.1 183 2.19e-19 FVLSSNQETQ LSPKKLTIDKEFEQYFSTLLM VAI07274.1 229 2.19e-19 VDDFMILPAG EKKKQLTIDQEFEQYFSKLML XP_022948410.1 209 2.63e-19 GRWTVNHEAQ SRDRTPTIDREFEQFFSMLML XP_013448883.1 193 5.02e-19 LLLNEEAESS TKPPPPTIDQEFEEYFSALML KZV44349.1 167 6.59e-19 LSSRRWSGDE DGGKRLTIDEEFEEYFSMLML EPS60070.1 159 8.63e-19 HLILSENREE GTIKKPTIDKEFEEYFSALLL XP_008448098.1 177 1.03e-18 GRWSVDSETE SKTVKPTIDQEFEQYFSVLLP SLDP EEC74952.1 245 2.70e-18 ILPRGQNSIH DEKNKLTIDQEFEQYFTRLML OAE24336.1 554 1.85e-17 SKTQGKSEAQ LGKRPPTIDDDFDQYFAQLML XP_010558336.1 217 4.11e-17 RWSVSTRDAG EGTRKPTIDQDFEQFFSSFLV KFK24705.1 154 1.13e-16 SRWSISSQDS EEEATTTIDKEFEEYFSTLMM EFJ36024.1 639 1.22e-16 ILSSGRQTSQ VEKKIPTIDDEFEEYFRQLML XP_017215985.1 233 2.61e-16 GWDVKNQEYQ PAGEKPTIDKDFEDYFSDLMI XP_023544624.1 170 7.90e-16 GRWSIDPEAE SKIITPTIDQEFEQYFSGILP LDP XP_018806280.1 224 1.13e-15 GRWTVNQEAP SGTRKPTIDQEFEQFLCRMQV C XP_024401192.1 382 4.33e-15 GRQSQVEAVQ DDAVAPTIDRDFDEYFAKLML -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SGTRKPTIDQEFEQYFSMLML MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- OAY41326.1 1.2e-27 174_[1] XP_021622766.1 1.2e-27 216_[1] XP_023913884.1 3.6e-27 224_[1] XP_022742854.1 1.3e-26 232_[1] XP_015896979.1 2e-26 225_[1] XP_021650240.1 3.1e-26 228_[1] XP_008803152.1 3.3e-26 318_[1] XP_010528448.1 4.5e-26 159_[1] RWW70318.1 8.8e-26 124_[1] TKS09656.1 8.8e-26 240_[1] TKR66562.1 8.8e-26 236_[1] GAV76568.1 1.1e-25 243_[1] XP_006410959.1 1.1e-25 170_[1] RVW33794.1 1.6e-25 239_[1] XP_024028595.1 1.9e-25 215_[1] XP_010256878.1 2.2e-25 240_[1] XP_022747248.1 4e-25 228_[1] XP_012442486.1 4e-25 261_[1] XP_002531564.2 8e-25 240_[1] XP_027336786.1 9.6e-25 232_[1] XP_010937591.1 1.1e-24 259_[1] XP_021289458.1 1.1e-24 232_[1] TEY25303.1 1.3e-24 222_[1] XP_021691173.1 1.9e-24 206_[1]_25 XP_022846646.1 2.6e-24 224_[1] XP_007134047.1 2.6e-24 230_[1] OVA17828.1 2.6e-24 247_[1] PKI43461.1 3e-24 220_[1] VDD15356.1 3e-24 359_[1] XP_027176296.1 4.1e-24 221_[1] PIA54706.1 4.1e-24 242_[1] PON90845.1 4.1e-24 224_[1] XP_010529822.1 4.8e-24 178_[1] XP_010047842.1 5.6e-24 222_[1] RWR86109.1 6.6e-24 232_[1] XP_026417177.1 1e-23 222_[1] AAL35819.1 1e-23 181_[1] XP_027149457.1 1.2e-23 211_[1] XP_012074964.1 1.4e-23 236_[1] GAY47919.1 1.6e-23 263_[1] PWA88889.1 1.8e-23 117_[1] XP_022039957.1 1.8e-23 161_[1] XP_023734875.1 1.8e-23 189_[1] PIN04755.1 1.8e-23 206_[1] XP_022983598.1 2.1e-23 232_[1] XP_015960799.1 2.4e-23 168_[1] XP_009798034.1 2.4e-23 238_[1] XP_028773013.1 2.4e-23 260_[1] XP_004137783.2 2.8e-23 326_[1] TKY63306.1 3.2e-23 241_[1] OUZ99277.1 3.7e-23 208_[1] XP_021856950.1 9.5e-23 183_[1] XP_021741222.1 1.4e-22 184_[1] XP_020108001.1 1.6e-22 225_[1] XP_021744044.1 1.6e-22 185_[1] XP_024982170.1 2.6e-22 218_[1] XP_020268040.1 3e-22 153_[1] PIN03316.1 3e-22 189_[1] RLN19347.1 3.4e-22 242_[1] OAO95598.1 3.4e-22 180_[1] XP_008240727.1 3.8e-22 210_[1] XP_020553487.1 4.3e-22 223_[1] XP_004302767.1 4.8e-22 235_[1] XP_017416333.1 4.8e-22 211_[1] XP_027353450.1 4.8e-22 214_[1] RXI02216.1 4.8e-22 236_[1] XP_024189435.1 4.8e-22 237_[1] XP_004514391.1 5.5e-22 217_[1] OEL29447.1 7.8e-22 338_[1] RID43060.1 7.8e-22 175_[1] XP_019162543.1 7.8e-22 223_[1] XP_028783417.1 7.8e-22 186_[1] XP_022145567.1 7.8e-22 227_[1] XP_010037822.1 8.8e-22 236_[1] TKY66008.1 8.8e-22 205_[1] XP_006349495.1 1.6e-21 239_[1] XP_010678090.1 2e-21 207_[1] XP_019459351.1 2.2e-21 217_[1] OMO66336.1 2.5e-21 228_[1] ADE76868.1 2.8e-21 380_[1] XP_006398684.1 3.8e-21 181_[1] XP_021307618.1 4.3e-21 272_[1] XP_018841755.1 4.3e-21 201_[1] XP_012832023.1 4.3e-21 173_[1] XP_011077640.1 4.3e-21 264_[1] PKI39361.1 4.8e-21 242_[1] PHT70537.1 4.8e-21 251_[1] NP_001354359.1 5.3e-21 245_[1] XP_010543288.1 5.9e-21 179_[1] XP_020593816.1 7.3e-21 203_[1] RAL39303.1 9.1e-21 189_[1]_1 XP_014752653.1 1e-20 225_[1] XP_012850185.1 1e-20 183_[1] KFK36656.1 1.2e-20 176_[1] PSS34997.1 2.3e-20 240_[1] XP_018681881.1 3.8e-20 131_[1] TEY72131.1 4.7e-20 228_[1] XP_028119329.1 6.9e-20 220_[1] XP_022143715.1 1.8e-19 148_[1] PNX96427.1 2e-19 194_[1] PSS23773.1 2.2e-19 182_[1] VAI07274.1 2.2e-19 228_[1] XP_022948410.1 2.6e-19 208_[1] XP_013448883.1 5e-19 192_[1] KZV44349.1 6.6e-19 166_[1] EPS60070.1 8.6e-19 158_[1] XP_008448098.1 1e-18 176_[1]_4 EEC74952.1 2.7e-18 244_[1] OAE24336.1 1.8e-17 553_[1] XP_010558336.1 4.1e-17 216_[1] KFK24705.1 1.1e-16 153_[1] EFJ36024.1 1.2e-16 638_[1] XP_017215985.1 2.6e-16 232_[1] XP_023544624.1 7.9e-16 169_[1]_3 XP_018806280.1 1.1e-15 223_[1]_1 XP_024401192.1 4.3e-15 381_[1] -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SGTRKPTIDQEFEQYFSMLML MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF SGTRKPTIDQEFEQYFSMLML width=21 seqs=116 OAY41326.1 ( 175) PGTRKPTIDQEFEQYFSMLML 1 XP_021622766.1 ( 217) PGTRKPTIDQEFEQYFSMLML 1 XP_023913884.1 ( 225) SGTRKPTIDQEFEQYFSMLML 1 XP_022742854.1 ( 233) QTTRKPTIDQEFEQYFSMLML 1 XP_015896979.1 ( 226) SGARKPTIDQEFEQYFSMLML 1 XP_021650240.1 ( 229) RGTRKPTIDQEFEQYFSMLML 1 XP_008803152.1 ( 319) LGARKPTIDQEFEQYFSMLML 1 XP_010528448.1 ( 160) QNTRKPTIDQEFEQYFSMLML 1 RWW70318.1 ( 125) LGTRKPTIDKEFEQYFSMLML 1 TKS09656.1 ( 241) SGPRKPTIDQEFEQYFSMLML 1 TKR66562.1 ( 237) SGPRKPTIDQEFEQYFSMLML 1 GAV76568.1 ( 244) QGTWKPTIDQEFEQYFSMLML 1 XP_006410959.1 ( 171) QGTKKPTIDQEFEQYFSTLML 1 RVW33794.1 ( 240) IGTRKPTIDQEFEQYFSMLML 1 XP_024028595.1 ( 216) SGSRKPTIDQEFEQYFSMLML 1 XP_010256878.1 ( 241) LGAKKPTIDQEFEQYFSMLML 1 XP_022747248.1 ( 229) QTRRKPTIDQEFEQYFSMLML 1 XP_012442486.1 ( 262) QTKRKPTIDQEFEQYFSMLML 1 XP_002531564.2 ( 241) PGTIKPTIDQEFEQYFSMLML 1 XP_027336786.1 ( 233) SSTRPPTIDQEFEQYFSMLML 1 XP_010937591.1 ( 260) LDARKPTIDQEFEQYFSMLML 1 XP_021289458.1 ( 233) QTARKPTIDQEFEQYFSTLML 1 TEY25303.1 ( 223) EGTRKPTIDQEFEQYFSALML 1 XP_021691173.1 ( 207) PGTXKPTIDQEFEQYFSMLML 1 XP_022846646.1 ( 225) PGTKKLTIDKEFEQYFSMLML 1 XP_007134047.1 ( 231) SGTKAPTIDQEFEQYFSMLML 1 OVA17828.1 ( 248) VDTRKPTIDQEFEQYFSMLMM 1 PKI43461.1 ( 221) ATTRKPTIDKEFEQYFSMLML 1 VDD15356.1 ( 360) DGTKKPTIDQEFEQYFSTLML 1 XP_027176296.1 ( 222) QGAKKLTIDKEFEQYFSMLML 1 PIA54706.1 ( 243) AGMRKPTIDQEFEQYFSMLML 1 PON90845.1 ( 225) SDSRKPTIDQEFEQYFSMLML 1 XP_010529822.1 ( 179) QNTMKPTIDQEFEQYFSMLML 1 XP_010047842.1 ( 223) HSTRRPTIDQEFEQYFSMLML 1 RWR86109.1 ( 233) LSARKPTIDQEFEQYFSTLML 1 XP_026417177.1 ( 223) VDSRKPTIDQEFEQYFSMLML 1 AAL35819.1 ( 182) HETKKPTIDQEFEQYFSTLML 1 XP_027149457.1 ( 212) QSTKKLTIDKEFEQYFSMLML 1 XP_012074964.1 ( 237) PVAKKPTIDQEFEQYFSMLML 1 GAY47919.1 ( 264) SGKRKPTIDQEFEQYFSSLML 1 PWA88889.1 ( 118) QGTEKLTIDKEFEQYFSMLML 1 XP_022039957.1 ( 162) QGTEKLTIDKEFEQYFSMLML 1 XP_023734875.1 ( 190) QGTEKLTIDKEFEQYFSMLML 1 PIN04755.1 ( 207) QGTEKLTIDKEFEQYFSMLML 1 XP_022983598.1 ( 233) SSARAPTIDQEFEQYFSMLML 1 XP_015960799.1 ( 169) SSTRPPTIDQEFEEYFSMLML 1 XP_009798034.1 ( 239) PGPKKLTIDKEFEQYFSMLML 1 XP_028773013.1 ( 261) SSTRPPTIDQEFEEYFSMLML 1 XP_004137783.2 ( 327) SRARAPTIDQEFEQYFSMLML 1 TKY63306.1 ( 242) SSTTPPTIDQEFEQYFSMLML 1 OUZ99277.1 ( 209) LGARKPTIDQEFEKYFSMLML 1 XP_021856950.1 ( 184) VGRQKPTIDQEFEQYFSTLML 1 XP_021741222.1 ( 185) MGRQKPTIDQEFEQYFSTLML 1 XP_020108001.1 ( 226) LGAQKLTIDQEFEQYFSTLML 1 XP_021744044.1 ( 186) RGRQKPTIDQEFEQYFSTLML 1 XP_024982170.1 ( 219) QGTEKMTIDKEFEQYFSMLML 1 XP_020268040.1 ( 154) LGTSKPTIDQEFEQYFSALML 1 PIN03316.1 ( 190) QESKKLTIDKEFEQYFSMLML 1 RLN19347.1 ( 243) QGEKKLTIDQEFEQYFSNLML 1 OAO95598.1 ( 181) EATTKPTIDQEFEQYFSTLMM 1 XP_008240727.1 ( 211) ASNRKPTIDQEFEQYFSTLML 1 XP_020553487.1 ( 224) PATRKLTIDKEFEQYFSSLML 1 XP_004302767.1 ( 236) GSSRKPTIDQEFEQYFSSLML 1 XP_017416333.1 ( 212) SNSRPPTIDQEFEEYFSMLML 1 XP_027353450.1 ( 215) SNSRPPTIDQEFEEYFSMLML 1 RXI02216.1 ( 237) GSSRKPTIDQEFEQYFSSLML 1 XP_024189435.1 ( 238) GSSRKPTIDQEFEQYFSSLML 1 XP_004514391.1 ( 218) SSTRPPTIDQEFEEYFSALML 1 OEL29447.1 ( 339) HGEKKLTIDQEFEQYFSNLML 1 RID43060.1 ( 176) EATKKPTIDQEFEEYFSTLMM 1 XP_019162543.1 ( 224) EGAKKLTIDKEFEQYFGMLML 1 XP_028783417.1 ( 187) SNARPPTIDEEFEQYFSMLML 1 XP_022145567.1 ( 228) SRAMTPTIDQEFEQYFSMLML 1 XP_010037822.1 ( 237) HRTRKPTIDQEFEDYFSTLMM 1 TKY66008.1 ( 206) SSSKPPTIDQEFEEYFSMLML 1 XP_006349495.1 ( 240) PSSTKLTIDKEFEQYFSMLML 1 XP_010678090.1 ( 208) MGRRKETIDQEFEQYFSTLML 1 XP_019459351.1 ( 218) SSTRPPTIDLEFEQYFSTLML 1 OMO66336.1 ( 229) KTTRRPTIDQEFEQYFATLML 1 ADE76868.1 ( 381) TGSRPPTIDKDFEQYFSMLML 1 XP_006398684.1 ( 182) EATTKPTIDQEFEEYFSTLMM 1 XP_021307618.1 ( 273) HSEKKLTIDQEFEQYFSNLML 1 XP_018841755.1 ( 202) PGTRKQTIDQEFEQFFSNLML 1 XP_012832023.1 ( 174) EDTKKLTIDKEFEEYFSMLMM 1 XP_011077640.1 ( 265) QEGKKLTIDKEFEQYFAMLML 1 PKI39361.1 ( 243) SAPRKPTIDQEFEEYFSSLMM 1 PHT70537.1 ( 252) PSSTKLTIDKEFEQYFSMLMM 1 NP_001354359.1 ( 246) HGEKKLTIDQEFEQYFANLML 1 XP_010543288.1 ( 180) QDTREPTIDQEFEQYFSSLMM 1 XP_020593816.1 ( 204) VGARKLTIDQEFEQYFSSLLL 1 RAL39303.1 ( 190) EGKKKLTIDKEFEQYFGTLML 1 XP_014752653.1 ( 226) GEKKKLTIDQEFEQYFSKLML 1 XP_012850185.1 ( 184) QESKKLTIDKEFEEYFSMLMM 1 KFK36656.1 ( 177) NDIKKPTIDQEFEEYFSTLML 1 PSS34997.1 ( 241) STSKNLTIDKEFEQYFSMLML 1 XP_018681881.1 ( 132) LGARKPTIGKESEQYFSMLML 1 TEY72131.1 ( 229) EGKKKLTIDNEFEQFFSMLML 1 XP_028119329.1 ( 221) LSPKKLTIDKEFEQYFSMLTL 1 XP_022143715.1 ( 149) SKTLKPTIDQEFEQYFSVLLL 1 PNX96427.1 ( 195) SSIRPPTIDEEFEEYFSALML 1 PSS23773.1 ( 183) LSPKKLTIDKEFEQYFSTLLM 1 VAI07274.1 ( 229) EKKKQLTIDQEFEQYFSKLML 1 XP_022948410.1 ( 209) SRDRTPTIDREFEQFFSMLML 1 XP_013448883.1 ( 193) TKPPPPTIDQEFEEYFSALML 1 KZV44349.1 ( 167) DGGKRLTIDEEFEEYFSMLML 1 EPS60070.1 ( 159) GTIKKPTIDKEFEEYFSALLL 1 XP_008448098.1 ( 177) SKTVKPTIDQEFEQYFSVLLP 1 EEC74952.1 ( 245) DEKNKLTIDQEFEQYFTRLML 1 OAE24336.1 ( 554) LGKRPPTIDDDFDQYFAQLML 1 XP_010558336.1 ( 217) EGTRKPTIDQDFEQFFSSFLV 1 KFK24705.1 ( 154) EEEATTTIDKEFEEYFSTLMM 1 EFJ36024.1 ( 639) VEKKIPTIDDEFEEYFRQLML 1 XP_017215985.1 ( 233) PAGEKPTIDKDFEDYFSDLMI 1 XP_023544624.1 ( 170) SKIITPTIDQEFEQYFSGILP 1 XP_018806280.1 ( 224) SGTRKPTIDQEFEQFLCRMQV 1 XP_024401192.1 ( 382) DDAVAPTIDRDFDEYFAKLML 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SGTRKPTIDQEFEQYFSMLML MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 20 w= 21 n= 26237 bayes= 9.06782 E= 2.6e-1823 -65 -556 -105 -6 -529 -34 97 -206 -191 35 -66 -219 130 201 -75 87 -117 -1 -481 -467 19 -582 -12 -48 -560 292 -381 -504 -32 -516 -476 -31 -480 -329 6 42 57 -210 -512 -495 168 -552 -266 -108 -531 -103 -362 -25 45 -485 -156 -220 54 -303 36 -5 306 -416 -482 -470 -173 -509 -404 -82 -489 -420 -345 -116 219 -277 -65 -214 -198 -13 371 -313 -4 -119 -9 -440 -45 -719 -742 -336 -790 -650 -498 -219 366 -639 -615 -257 155 -196 -17 -694 -43 -607 -621 -658 -331 -567 -586 -341 -590 -527 -523 -521 -496 162 -174 -574 414 -218 -461 -535 -224 -474 -592 -635 -956 -948 -1033 -1156 -1018 -876 -948 -1096 -1060 -1041 -1135 -1048 -914 -1025 -939 -1112 444 -1050 -880 -1003 -949 -930 -1033 -1152 -981 -881 -948 464 -1057 -941 -1015 -1048 -915 -1024 -940 -1126 -968 -801 -878 -991 -957 -947 372 -1086 -1013 -263 -932 -1087 -1042 -1036 -1125 -975 -911 -1009 -931 -1098 -983 -1045 -877 -996 -557 -739 -211 -188 -809 -653 -505 -658 205 -307 -628 -256 -684 401 -65 -701 -562 -618 -636 -670 -478 -622 -172 327 -646 -538 -513 -531 -601 -644 -617 -500 -646 -421 -544 -676 -549 -542 -557 -630 -866 -893 -1017 -1119 464 -858 -836 -956 -1022 -914 -979 -992 -897 -971 -904 -391 -932 -933 -711 -654 -468 -607 -247 328 -630 -525 -500 -515 -597 -631 -604 -486 -639 -410 -532 -665 -537 -529 -541 -615 -474 -956 -182 80 -890 -639 -616 -706 -252 -721 -690 -600 -613 425 -571 -693 -578 -618 -825 -785 -796 -758 -948 -979 21 -847 -532 -707 -855 -676 -716 -782 -844 -759 -735 -901 -789 -706 -382 485 -874 -852 -1002 -1080 464 -867 -761 -754 -981 -309 -767 -949 -883 -918 -869 -1025 -901 -794 -613 -539 -1 -122 -879 -907 -801 -156 -793 -757 -843 -795 -744 -733 -664 -751 -200 279 -220 -594 -754 -831 20 -561 -266 -391 -537 -237 -367 -475 -89 -489 423 -32 -462 -98 -76 -74 191 -122 -489 -475 -679 -704 -1036 -978 -199 -903 -807 -183 -888 363 -140 -936 -822 -759 -771 -976 -701 -465 -588 -674 -443 -436 -636 -665 -449 -550 -536 -273 -549 -108 507 -580 -537 -327 -535 -618 -314 -326 -322 -398 -529 -571 -808 -748 -398 -717 -627 -164 -659 344 182 -722 -132 -580 -558 -754 -545 -116 -495 -564 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SGTRKPTIDQEFEQYFSMLML MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 20 w= 21 nsites= 116 E= 2.6e-1823 0.025862 0.000000 0.034483 0.094828 0.000000 0.043103 0.051724 0.008621 0.008621 0.103448 0.017241 0.008621 0.103448 0.172414 0.017241 0.250000 0.017241 0.043103 0.000000 0.000000 0.051724 0.000000 0.068966 0.068966 0.000000 0.431034 0.000000 0.000000 0.043103 0.000000 0.000000 0.043103 0.000000 0.000000 0.034483 0.181034 0.068966 0.008621 0.000000 0.000000 0.155172 0.000000 0.008621 0.043103 0.000000 0.025862 0.000000 0.034483 0.077586 0.000000 0.008621 0.008621 0.060345 0.000000 0.043103 0.129310 0.405172 0.000000 0.000000 0.000000 0.009025 0.000181 0.000647 0.052581 0.000342 0.000466 0.000222 0.017587 0.276366 0.009292 0.017479 0.009099 0.008965 0.034840 0.483060 0.009751 0.043502 0.017613 0.008698 0.000285 0.034483 0.000000 0.000000 0.008621 0.000000 0.000000 0.000000 0.008621 0.750000 0.000000 0.000000 0.008621 0.120690 0.008621 0.025862 0.000000 0.034483 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.008621 0.000000 0.000000 0.000000 0.000000 0.000000 0.267241 0.008621 0.000000 0.698276 0.008621 0.000000 0.000000 0.008621 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.991379 0.000000 0.000000 0.008621 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.017241 0.025862 0.000000 0.000000 0.000000 0.000000 0.241379 0.008621 0.000000 0.008621 0.000000 0.681034 0.017241 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.043103 0.956897 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.991379 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.008621 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.017241 0.982759 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.017241 0.163793 0.000000 0.000000 0.000000 0.000000 0.008621 0.000000 0.000000 0.000000 0.000000 0.810345 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.043103 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.956897 0.000000 0.000000 0.000000 0.000000 0.991379 0.000000 0.000000 0.000000 0.000000 0.008621 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.043103 0.008621 0.000000 0.000000 0.000000 0.017241 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.008621 0.913793 0.008621 0.000000 0.000000 0.000000 0.051724 0.000000 0.008621 0.000000 0.000000 0.008621 0.000000 0.000000 0.025862 0.000000 0.551724 0.043103 0.000000 0.017241 0.017241 0.077586 0.181034 0.017241 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.008621 0.000000 0.000000 0.008621 0.000000 0.974138 0.008621 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.060345 0.922414 0.000000 0.000000 0.008621 0.000000 0.000000 0.008621 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.008621 0.000000 0.853448 0.103448 0.000000 0.017241 0.000000 0.000000 0.000000 0.000000 0.017241 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SGTRKPTIDQEFEQYFSMLML MEME-1 regular expression -------------------------------------------------------------------------------- SGT[RK]K[PL]TID[QK]EFEQYFSMLML -------------------------------------------------------------------------------- Time 50.34 secs. ******************************************************************************** ******************************************************************************** MOTIF YVLSSGRWSVNQEAQ MEME-2 width = 15 sites = 101 llr = 3053 E-value = 5.5e-891 ******************************************************************************** -------------------------------------------------------------------------------- Motif YVLSSGRWSVNQEAQ MEME-2 Description -------------------------------------------------------------------------------- Simplified A :::::::::::::5: pos.-specific C ::::::::::::::: probability D ::::::::::1:41: matrix E ::::::::::::4:1 F 2:::::::::::::: G :::::9::::1:::: H :::::::::::1::: I :1:::::::1::::: K ::::::::::::::: L ::9::::::1::::: M ::::::::::::::: N ::::::::2:7:::: P ::::::::::::::1 Q :::::::::::71:5 R ::::::9::::1::1 S :::aa:::4::::11 T ::::::::2::::1: V :8:::::::7::::: W :::::::9::::::: Y 7:::::::::::::: bits 6.8 6.1 * 5.4 * 4.8 * Relative 4.1 ** Entropy 3.4 *** *** (43.6 bits) 2.7 ******** * * 2.0 ******** ****** 1.4 *************** 0.7 *************** 0.0 --------------- Multilevel YVLSSGRWSVNQDAQ consensus F E sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YVLSSGRWSVNQEAQ MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- --------------- XP_021622766.1 202 8.21e-20 LYSNGVNPNR YVLSSGRWSVNQDAQ PGTRKPTIDQ XP_021650240.1 214 8.21e-20 LNSNGVNPNV YVLSSGRWSVNQDAQ RGTRKPTIDQ RVW33794.1 225 8.21e-20 PYSSGMKPNN YVLSSGRWSVNQDAQ IGTRKPTIDQ XP_024189435.1 222 2.17e-19 IYSNSLNPHT YVLSSGRWSVNQEAQ SGSSRKPTID XP_027336786.1 218 2.17e-19 LFAQGGNRNM YVLSSGRWSVNQEAQ SSTRPPTIDQ PON90845.1 210 2.17e-19 LCASGLNRNV YVLSSGRWSVNQEAQ SDSRKPTIDQ XP_012074964.1 222 2.17e-19 LYPKGVDSNV YVLSSGRWNVNQDAQ PVAKKPTIDQ XP_017416333.1 197 2.51e-19 LFSSGVDPNV YVLSSGRWNVNQEAQ SNSRPPTIDQ TKY66008.1 191 2.51e-19 LFSTGVNPNV YVLSSGRWNVNQEAQ SSSKPPTIDQ TKY63306.1 227 2.51e-19 LFSNGENRNM YVLSSGRWNVNQEAQ SSTTPPTIDQ XP_011077640.1 250 7.63e-19 LYSNGVAPGN YVLSSGRWSVNQDTQ QEGKKLTIDK XP_015896979.1 211 7.63e-19 LYSNRLNPNT YVLSSGRWSVNQDTQ SGARKPTIDQ XP_004302767.1 220 1.73e-18 IYSNSLNPHA YILSSGRWSVNQEAQ SGSSRKPTID XP_012442486.1 247 1.73e-18 LNCDGANPNV YILSSGRWSVNQEAQ QTKRKPTIDQ XP_018806280.1 209 1.98e-18 LYSNGINPNK YVLSSGRWTVNQEAP SGTRKPTIDQ XP_004514391.1 203 1.98e-18 LCSNGVNPDT YVLSSGRWDVNQEAQ SSTRPPTIDQ XP_007134047.1 216 1.98e-18 LFSKRENSHK YVLSSGRWDVNQEAQ SGTKAPTIDQ OMO66336.1 214 2.32e-18 LNSNGANQNV YVLSSGRWSVNQEAP KTTRRPTIDQ XP_022742854.1 218 2.32e-18 LNCDGANPNV YVLSSGRWSVNQEAP QTTRKPTIDQ XP_022948410.1 194 2.64e-18 FRSNGLNPNT YVLSSGRWTVNHEAQ SRDRTPTIDR XP_027353450.1 200 3.82e-18 LFSNGVNPNM YVLSSGRWEVNQEAQ SNSRPPTIDQ XP_028773013.1 246 3.82e-18 LYSSGVNPNV YVLSSGRWEVNQEAQ SSTRPPTIDQ PHT70537.1 237 4.54e-18 LLNSNVNPNN YVLSSGRWTVNQDSQ PSSTKLTIDK XP_006349495.1 225 4.54e-18 LLNANVNPSN YVLSSGRWTVNQDSQ PSSTKLTIDK XP_010256878.1 226 6.08e-18 LYSNGATSNL FVLSSGRWSVNQEAR LGAKKPTIDQ XP_002531564.2 226 7.11e-18 LSANEANPNM FILSSGRWTVNQDAQ PGTIKPTIDQ RXI02216.1 220 8.64e-18 IYPNGLKPNT YVLSSGRWSVNQEGQ SAGSSRKPTI PIN04755.1 192 1.19e-17 LYANGVVPNN YILSSGRWSVNQDTQ QGTEKLTIDK PSS34997.1 226 1.39e-17 LYSDETPQNN YVLSSGRWSVNQENQ STSKNLTIDK XP_022846646.1 208 1.64e-17 LYLNDVASSS YVLSSGRWTVNQDAD TQPGTKKLTI XP_021691173.1 192 1.88e-17 LYSNGVNPNM YVLSSGKWSVNQDAQ PGTXKPTIDQ XP_028119329.1 206 2.17e-17 LCSDEPSPNN YVLSSGRWSVNQETP LSPKKLTIDK PIN03316.1 175 2.17e-17 LYSNGVASSQ YVLSSGRWPVDQDAQ QESKKLTIDK OVA17828.1 233 2.17e-17 LYSNEATSKL YVLSSGRWNINQDAR VDTRKPTIDQ TEY25303.1 208 3.35e-17 LYSNEATDCN FVLSSGRWSVNQDSQ EGTRKPTIDQ XP_023913884.1 210 3.77e-17 LYSNGSNPNT YVLSSRRWNVNQDAQ SGTRKPTIDQ XP_021289458.1 218 4.34e-17 LNTNGANPNV YVLSSGRWSVNQGAS QTARKPTIDQ XP_027149457.1 197 5.56e-17 LYSNGVNPNN YVLSSGRWTLNQDTQ QSTKKLTIDK XP_023734875.1 175 1.32e-16 FCSNDVIPDN FVLSSGRWNVNQDIQ QGTEKLTIDK XP_010528448.1 144 1.50e-16 DEDVKDYNAT YVLSSGRWTVNQDSS RQNTRKPTID XP_018841755.1 187 1.74e-16 DSHGVNPTNM YVLSSERWTVGQDAQ PGTRKQTIDQ XP_010047842.1 208 1.74e-16 IYSNGEPSNN FVLSSGRWIVNREAQ HSTRRPTIDQ XP_024982170.1 204 1.99e-16 FCSDGVIPDN FVLSSGRWNVNQDTE QGTEKMTIDK GAY47919.1 249 2.28e-16 LDSKEGNPNV YVLSSGRWSHNQETQ SGKRKPTIDQ XP_006410959.1 155 2.61e-16 EANGCSNAAN YVLSSGRWTVNQDST RQGTKKPTID XP_028783417.1 172 3.00e-16 FSTHGAIPNM YILSSGKWNVNQEAQ SNARPPTIDE RWR86109.1 218 5.99e-16 LYSNDVPSNL YVLSSGRWSVGPDAR LSARKPTIDQ KFK36656.1 161 5.99e-16 EAKGCSSDVN YVLSSGRWTVNQDSI ENDIKKPTID AAL35819.1 165 5.99e-16 VKGCSSNAAK FVLSSGRWTVNQDDS TLHETKKPTI XP_022747248.1 214 8.78e-16 LNSNGAKPNV YVLSSGRWSVNLEAP QTRRKPTIDQ XP_020553487.1 209 1.13e-15 LYSSGVAPSN YVLSSGRWSVTHDTQ PATRKLTIDK XP_019162543.1 209 1.28e-15 LYSNGIAPDN FVLSSGRWEVGQDTQ EGAKKLTIDK XP_008240727.1 192 2.11e-15 IYPIGSNTNK YILSSGRWSVNQDNS DVQSASNRKP XP_022983598.1 218 3.02e-15 FYSNGLDPNA YILSSGRWTVNNEDQ SSARAPTIDQ VDD15356.1 344 3.02e-15 EANGCSNAAK YVLSSGRWTVDQDST QDGTKKPTID XP_012832023.1 159 3.41e-15 IIDQFTGNDA YVLSSGRWPVHQDNQ EDTKKLTIDK XP_027176296.1 207 3.41e-15 LYSNGATPNN YVLSSERWTLNQDTQ QGAKKLTIDK XP_004137783.2 312 3.41e-15 FYSNGLNPNT YILSSGRWAINHEAQ SRARAPTIDQ XP_009798034.1 224 3.41e-15 LYSNGVNPNN YVLSSGRWPVNQDPE PGPKKLTIDK XP_022039957.1 142 3.85e-15 FCSNAVISNN SVLSSGRWNVNQDAA AAAAEQGTEK TKR66562.1 222 3.85e-15 LYSNGVNPNV HALSSGRWAVNQEAQ SGPRKPTIDQ TEY72131.1 210 4.34e-15 YSNGAAPGGT FILSSGRWSVDQGAR AMQEEGKKKL XP_022145567.1 213 5.52e-15 FYSNGLNQNT YLLSSGRWGVNHEAQ SRAMTPTIDQ PKI43461.1 206 5.52e-15 LYSSGMNPNS YVLSSGRWIVEQEGQ ATTRKPTIDK XP_015960799.1 154 6.24e-15 LLSNGVDPNM YVLSSGRRNVNREAQ SSTRPPTIDQ XP_010529822.1 163 1.82e-14 DDEVKDHNAT YVLSSGRWAVNRDSS LQNTMKPTID PIA54706.1 228 2.04e-14 TLYSNGPSDL FVLSSGRWNINKDAE AGMRKPTIDQ XP_019459351.1 203 2.56e-14 LYSNKVNPHA YVLSSGQWNVDKEAQ SSTRPPTIDL XP_012850185.1 168 7.80e-14 EESTDKELEN YVLSSGRWSVNNQGN EQESKKLTID XP_023544624.1 155 1.08e-13 LLLPTDSKHD FVLSSGRWSIDPEAE SKIITPTIDQ XP_024028595.1 201 1.21e-13 LYANGLNPNE YVISSGRRTVNQEDQ SGSRKPTIDQ XP_010678090.1 193 1.34e-13 LSSSGVNTNL YVPSPDRWNVDQEAQ MGRRKETIDQ TKS09656.1 226 1.34e-13 LYSNELNLNG HVLSSEGWTVNQEAQ SGPRKPTIDQ PWA88889.1 103 1.86e-13 CPDGVIISNN YVLSSGRWDIIQDTE QGTEKLTIDK OUZ99277.1 194 2.30e-13 LSWNGSNPNS YVLSSGRWSIKQNTR LGARKPTIDQ XP_008448098.1 162 2.85e-13 LLLPTDSKQN FVLSSGRWSVDSETE SKTVKPTIDQ GAV76568.1 229 2.85e-13 LYSSGLNPNS YVHSFGRWSANRDAQ QGTWKPTIDQ XP_026417177.1 208 3.17e-13 LDPNEAESNL FVLSSGRWDVDPDSR VDSRKPTIDQ RAL39303.1 174 6.56e-13 LYSNGVIPNS FVLSSGRWKVGQQES EEGKKKLTID XP_020108001.1 211 1.81e-12 CSDAEILSNA FVLPSGQWSLGQEAR LGAQKLTIDQ XP_022143715.1 132 2.97e-12 EECYRDSKHD FVLSSGRWNVDPPSE AESKTLKPTI XP_008803152.1 299 3.99e-12 LYSNDVTPDA FVLSSGRWSTGQGMF MFDARLGARK XP_010037822.1 222 4.40e-12 IYSNASKPDN LVLSSGRWNTNHDTL HRTRKPTIDQ ADE76868.1 366 6.48e-12 MPDTGETLPL FVLSSGRVTQNKDAR TGSRPPTIDK OAO95598.1 165 3.51e-11 LQEVLNPVES YILSSARWSVSNQDS KEATTKPTID XP_013448883.1 176 5.06e-11 LFSNGVNPDK YVLSSGRLLLNEEAE SSTKPPPPTI XP_010937591.1 245 5.54e-11 LYSNDVAPNA FVLPSGSWSTGHDAR LDARKPTIDQ PKI39361.1 228 6.64e-11 DEFFGLIRGN YVLSSGQLSMNEETQ SAPRKPTIDQ XP_021744044.1 171 1.48e-10 GQLEGLLSSS GIPSSDRWTVDREAH RGRQKPTIDQ XP_021856950.1 169 1.76e-10 EQLEGLLSST GMVSSERWTLNPEAQ VGRQKPTIDQ XP_020593816.1 188 1.92e-10 AETVILYSND VLLSSGRWNLGKGAP LVGARKLTID RID43060.1 160 2.29e-10 SCEDSNVEGS YTLSSARWSVSNQES EEATKKPTID OAE24336.1 536 1.59e-09 GSESNKPEPT FVLSSGRLSKTQGKS EAQLGKRPPT XP_006398684.1 166 1.73e-09 HSQDSNLKGS YTLSSAKWSVSNQDS EEATTKPTID XP_010558336.1 201 2.21e-09 LCCGDPDAGS FLLSSARWSVSTRDA GEGTRKPTID XP_020268040.1 139 5.32e-09 EEIYSNDVAP FLLASGKCSIEQDAR LGTSKPTIDQ KFK24705.1 139 7.29e-09 LQELMNPVGS YTLSSSRWSISSQDS EEEATTTIDK XP_024401192.1 367 9.21e-09 KLRSKELQHT FVLSSGRQSQVEAVQ DDAVAPTIDR PNX96427.1 179 3.61e-08 LISHGVIPDK YALSSGILILNQTEA DSSIRPPTID RWW70318.1 110 4.18e-08 LYSNDVAPHA LLVSPERWSSGRDAR LGTRKPTIDK XP_021741222.1 170 1.53e-07 EQLEGLLSSS GIPSSDRWIADGEGD MGRQKPTIDQ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YVLSSGRWSVNQEAQ MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- XP_021622766.1 8.2e-20 201_[2]_21 XP_021650240.1 8.2e-20 213_[2]_21 RVW33794.1 8.2e-20 224_[2]_21 XP_024189435.1 2.2e-19 221_[2]_22 XP_027336786.1 2.2e-19 217_[2]_21 PON90845.1 2.2e-19 209_[2]_21 XP_012074964.1 2.2e-19 221_[2]_21 XP_017416333.1 2.5e-19 196_[2]_21 TKY66008.1 2.5e-19 190_[2]_21 TKY63306.1 2.5e-19 226_[2]_21 XP_011077640.1 7.6e-19 249_[2]_21 XP_015896979.1 7.6e-19 210_[2]_21 XP_004302767.1 1.7e-18 219_[2]_22 XP_012442486.1 1.7e-18 246_[2]_21 XP_018806280.1 2e-18 208_[2]_22 XP_004514391.1 2e-18 202_[2]_21 XP_007134047.1 2e-18 215_[2]_21 OMO66336.1 2.3e-18 213_[2]_21 XP_022742854.1 2.3e-18 217_[2]_21 XP_022948410.1 2.6e-18 193_[2]_21 XP_027353450.1 3.8e-18 199_[2]_21 XP_028773013.1 3.8e-18 245_[2]_21 PHT70537.1 4.5e-18 236_[2]_21 XP_006349495.1 4.5e-18 224_[2]_21 XP_010256878.1 6.1e-18 225_[2]_21 XP_002531564.2 7.1e-18 225_[2]_21 RXI02216.1 8.6e-18 219_[2]_23 PIN04755.1 1.2e-17 191_[2]_21 PSS34997.1 1.4e-17 225_[2]_21 XP_022846646.1 1.6e-17 207_[2]_23 XP_021691173.1 1.9e-17 191_[2]_46 XP_028119329.1 2.2e-17 205_[2]_21 PIN03316.1 2.2e-17 174_[2]_21 OVA17828.1 2.2e-17 232_[2]_21 TEY25303.1 3.3e-17 207_[2]_21 XP_023913884.1 3.8e-17 209_[2]_21 XP_021289458.1 4.3e-17 217_[2]_21 XP_027149457.1 5.6e-17 196_[2]_21 XP_023734875.1 1.3e-16 174_[2]_21 XP_010528448.1 1.5e-16 143_[2]_22 XP_018841755.1 1.7e-16 186_[2]_21 XP_010047842.1 1.7e-16 207_[2]_21 XP_024982170.1 2e-16 203_[2]_21 GAY47919.1 2.3e-16 248_[2]_21 XP_006410959.1 2.6e-16 154_[2]_22 XP_028783417.1 3e-16 171_[2]_21 RWR86109.1 6e-16 217_[2]_21 KFK36656.1 6e-16 160_[2]_22 AAL35819.1 6e-16 164_[2]_23 XP_022747248.1 8.8e-16 213_[2]_21 XP_020553487.1 1.1e-15 208_[2]_21 XP_019162543.1 1.3e-15 208_[2]_21 XP_008240727.1 2.1e-15 191_[2]_25 XP_022983598.1 3e-15 217_[2]_21 VDD15356.1 3e-15 343_[2]_22 XP_012832023.1 3.4e-15 158_[2]_21 XP_027176296.1 3.4e-15 206_[2]_21 XP_004137783.2 3.4e-15 311_[2]_21 XP_009798034.1 3.4e-15 223_[2]_21 XP_022039957.1 3.8e-15 141_[2]_26 TKR66562.1 3.8e-15 221_[2]_21 TEY72131.1 4.3e-15 209_[2]_25 XP_022145567.1 5.5e-15 212_[2]_21 PKI43461.1 5.5e-15 205_[2]_21 XP_015960799.1 6.2e-15 153_[2]_21 XP_010529822.1 1.8e-14 162_[2]_22 PIA54706.1 2e-14 227_[2]_21 XP_019459351.1 2.6e-14 202_[2]_21 XP_012850185.1 7.8e-14 167_[2]_22 XP_023544624.1 1.1e-13 154_[2]_24 XP_024028595.1 1.2e-13 200_[2]_21 XP_010678090.1 1.3e-13 192_[2]_21 TKS09656.1 1.3e-13 225_[2]_21 PWA88889.1 1.9e-13 102_[2]_21 OUZ99277.1 2.3e-13 193_[2]_21 XP_008448098.1 2.8e-13 161_[2]_25 GAV76568.1 2.8e-13 228_[2]_21 XP_026417177.1 3.2e-13 207_[2]_21 RAL39303.1 6.6e-13 173_[2]_23 XP_020108001.1 1.8e-12 210_[2]_21 XP_022143715.1 3e-12 131_[2]_23 XP_008803152.1 4e-12 298_[2]_26 XP_010037822.1 4.4e-12 221_[2]_21 ADE76868.1 6.5e-12 365_[2]_21 OAO95598.1 3.5e-11 164_[2]_22 XP_013448883.1 5.1e-11 175_[2]_23 XP_010937591.1 5.5e-11 244_[2]_21 PKI39361.1 6.6e-11 227_[2]_21 XP_021744044.1 1.5e-10 170_[2]_21 XP_021856950.1 1.8e-10 168_[2]_21 XP_020593816.1 1.9e-10 187_[2]_22 RID43060.1 2.3e-10 159_[2]_22 OAE24336.1 1.6e-09 535_[2]_24 XP_006398684.1 1.7e-09 165_[2]_22 XP_010558336.1 2.2e-09 200_[2]_22 XP_020268040.1 5.3e-09 138_[2]_21 KFK24705.1 7.3e-09 138_[2]_21 XP_024401192.1 9.2e-09 366_[2]_21 PNX96427.1 3.6e-08 178_[2]_22 RWW70318.1 4.2e-08 109_[2]_21 XP_021741222.1 1.5e-07 169_[2]_21 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YVLSSGRWSVNQEAQ MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF YVLSSGRWSVNQEAQ width=15 seqs=101 XP_021622766.1 ( 202) YVLSSGRWSVNQDAQ 1 XP_021650240.1 ( 214) YVLSSGRWSVNQDAQ 1 RVW33794.1 ( 225) YVLSSGRWSVNQDAQ 1 XP_024189435.1 ( 222) YVLSSGRWSVNQEAQ 1 XP_027336786.1 ( 218) YVLSSGRWSVNQEAQ 1 PON90845.1 ( 210) YVLSSGRWSVNQEAQ 1 XP_012074964.1 ( 222) YVLSSGRWNVNQDAQ 1 XP_017416333.1 ( 197) YVLSSGRWNVNQEAQ 1 TKY66008.1 ( 191) YVLSSGRWNVNQEAQ 1 TKY63306.1 ( 227) YVLSSGRWNVNQEAQ 1 XP_011077640.1 ( 250) YVLSSGRWSVNQDTQ 1 XP_015896979.1 ( 211) YVLSSGRWSVNQDTQ 1 XP_004302767.1 ( 220) YILSSGRWSVNQEAQ 1 XP_012442486.1 ( 247) YILSSGRWSVNQEAQ 1 XP_018806280.1 ( 209) YVLSSGRWTVNQEAP 1 XP_004514391.1 ( 203) YVLSSGRWDVNQEAQ 1 XP_007134047.1 ( 216) YVLSSGRWDVNQEAQ 1 OMO66336.1 ( 214) YVLSSGRWSVNQEAP 1 XP_022742854.1 ( 218) YVLSSGRWSVNQEAP 1 XP_022948410.1 ( 194) YVLSSGRWTVNHEAQ 1 XP_027353450.1 ( 200) YVLSSGRWEVNQEAQ 1 XP_028773013.1 ( 246) YVLSSGRWEVNQEAQ 1 PHT70537.1 ( 237) YVLSSGRWTVNQDSQ 1 XP_006349495.1 ( 225) YVLSSGRWTVNQDSQ 1 XP_010256878.1 ( 226) FVLSSGRWSVNQEAR 1 XP_002531564.2 ( 226) FILSSGRWTVNQDAQ 1 RXI02216.1 ( 220) YVLSSGRWSVNQEGQ 1 PIN04755.1 ( 192) YILSSGRWSVNQDTQ 1 PSS34997.1 ( 226) YVLSSGRWSVNQENQ 1 XP_022846646.1 ( 208) YVLSSGRWTVNQDAD 1 XP_021691173.1 ( 192) YVLSSGKWSVNQDAQ 1 XP_028119329.1 ( 206) YVLSSGRWSVNQETP 1 PIN03316.1 ( 175) YVLSSGRWPVDQDAQ 1 OVA17828.1 ( 233) YVLSSGRWNINQDAR 1 TEY25303.1 ( 208) FVLSSGRWSVNQDSQ 1 XP_023913884.1 ( 210) YVLSSRRWNVNQDAQ 1 XP_021289458.1 ( 218) YVLSSGRWSVNQGAS 1 XP_027149457.1 ( 197) YVLSSGRWTLNQDTQ 1 XP_023734875.1 ( 175) FVLSSGRWNVNQDIQ 1 XP_010528448.1 ( 144) YVLSSGRWTVNQDSS 1 XP_018841755.1 ( 187) YVLSSERWTVGQDAQ 1 XP_010047842.1 ( 208) FVLSSGRWIVNREAQ 1 XP_024982170.1 ( 204) FVLSSGRWNVNQDTE 1 GAY47919.1 ( 249) YVLSSGRWSHNQETQ 1 XP_006410959.1 ( 155) YVLSSGRWTVNQDST 1 XP_028783417.1 ( 172) YILSSGKWNVNQEAQ 1 RWR86109.1 ( 218) YVLSSGRWSVGPDAR 1 KFK36656.1 ( 161) YVLSSGRWTVNQDSI 1 AAL35819.1 ( 165) FVLSSGRWTVNQDDS 1 XP_022747248.1 ( 214) YVLSSGRWSVNLEAP 1 XP_020553487.1 ( 209) YVLSSGRWSVTHDTQ 1 XP_019162543.1 ( 209) FVLSSGRWEVGQDTQ 1 XP_008240727.1 ( 192) YILSSGRWSVNQDNS 1 XP_022983598.1 ( 218) YILSSGRWTVNNEDQ 1 VDD15356.1 ( 344) YVLSSGRWTVDQDST 1 XP_012832023.1 ( 159) YVLSSGRWPVHQDNQ 1 XP_027176296.1 ( 207) YVLSSERWTLNQDTQ 1 XP_004137783.2 ( 312) YILSSGRWAINHEAQ 1 XP_009798034.1 ( 224) YVLSSGRWPVNQDPE 1 XP_022039957.1 ( 142) SVLSSGRWNVNQDAA 1 TKR66562.1 ( 222) HALSSGRWAVNQEAQ 1 TEY72131.1 ( 210) FILSSGRWSVDQGAR 1 XP_022145567.1 ( 213) YLLSSGRWGVNHEAQ 1 PKI43461.1 ( 206) YVLSSGRWIVEQEGQ 1 XP_015960799.1 ( 154) YVLSSGRRNVNREAQ 1 XP_010529822.1 ( 163) YVLSSGRWAVNRDSS 1 PIA54706.1 ( 228) FVLSSGRWNINKDAE 1 XP_019459351.1 ( 203) YVLSSGQWNVDKEAQ 1 XP_012850185.1 ( 168) YVLSSGRWSVNNQGN 1 XP_023544624.1 ( 155) FVLSSGRWSIDPEAE 1 XP_024028595.1 ( 201) YVISSGRRTVNQEDQ 1 XP_010678090.1 ( 193) YVPSPDRWNVDQEAQ 1 TKS09656.1 ( 226) HVLSSEGWTVNQEAQ 1 PWA88889.1 ( 103) YVLSSGRWDIIQDTE 1 OUZ99277.1 ( 194) YVLSSGRWSIKQNTR 1 XP_008448098.1 ( 162) FVLSSGRWSVDSETE 1 GAV76568.1 ( 229) YVHSFGRWSANRDAQ 1 XP_026417177.1 ( 208) FVLSSGRWDVDPDSR 1 RAL39303.1 ( 174) FVLSSGRWKVGQQES 1 XP_020108001.1 ( 211) FVLPSGQWSLGQEAR 1 XP_022143715.1 ( 132) FVLSSGRWNVDPPSE 1 XP_008803152.1 ( 299) FVLSSGRWSTGQGMF 1 XP_010037822.1 ( 222) LVLSSGRWNTNHDTL 1 ADE76868.1 ( 366) FVLSSGRVTQNKDAR 1 OAO95598.1 ( 165) YILSSARWSVSNQDS 1 XP_013448883.1 ( 176) YVLSSGRLLLNEEAE 1 XP_010937591.1 ( 245) FVLPSGSWSTGHDAR 1 PKI39361.1 ( 228) YVLSSGQLSMNEETQ 1 XP_021744044.1 ( 171) GIPSSDRWTVDREAH 1 XP_021856950.1 ( 169) GMVSSERWTLNPEAQ 1 XP_020593816.1 ( 188) VLLSSGRWNLGKGAP 1 RID43060.1 ( 160) YTLSSARWSVSNQES 1 OAE24336.1 ( 536) FVLSSGRLSKTQGKS 1 XP_006398684.1 ( 166) YTLSSAKWSVSNQDS 1 XP_010558336.1 ( 201) FLLSSARWSVSTRDA 1 XP_020268040.1 ( 139) FLLASGKCSIEQDAR 1 KFK24705.1 ( 139) YTLSSSRWSISSQDS 1 XP_024401192.1 ( 367) FVLSSGRQSQVEAVQ 1 PNX96427.1 ( 179) YALSSGILILNQTEA 1 RWW70318.1 ( 110) LLVSPERWSSGRDAR 1 XP_021741222.1 ( 170) GIPSSDRWIADGEGD 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YVLSSGRWSVNQEAQ MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 20 w= 15 n= 26933 bayes= 9.67092 E= 5.5e-891 -365 -449 -573 -569 247 -97 -20 -408 -498 -183 -420 -515 -510 -491 -426 -345 -453 -189 -229 432 -84 -340 -566 -558 -431 -512 -460 143 -498 -82 -152 -540 -461 -502 -407 -565 -71 414 -475 -551 -438 -484 -704 -644 -333 -619 -158 -130 -555 353 -210 -620 -68 -482 -455 -651 -453 -95 -419 -482 -177 -541 -884 -913 -808 -528 -798 -765 -861 -801 -753 -751 -100 -757 -739 287 -524 -594 -756 -840 -525 -695 -949 -1021 -199 -672 -848 -894 -952 -901 -893 -868 -101 -874 -835 288 -684 -752 -776 -791 -40 -518 -157 -133 -603 400 -493 -558 -480 -628 -556 -420 -528 -527 -189 -351 -486 -500 -471 -562 -370 -380 -573 -598 -542 -287 -291 -249 -78 -462 -473 -433 -414 -104 468 -398 -425 -494 -319 -491 -392 -200 -516 -541 -184 -443 -419 -405 -453 -157 -360 -467 -476 -272 -167 -555 -421 -249 665 -213 -58 -400 -108 -180 -493 -231 -393 -24 -213 -285 -434 135 -62 -356 -320 183 200 -430 -450 -460 -62 -272 -491 -484 -368 -440 -180 90 -275 -63 -160 -468 -387 -163 -331 -372 -76 411 -404 -487 -465 -552 36 -241 -587 51 -121 -208 -247 -611 -576 364 -536 -441 -464 -148 -126 -220 -497 -541 -290 -417 -499 -169 -498 -285 80 -402 -110 -262 -273 -77 -38 413 20 -302 -228 -385 -332 -481 -203 -899 247 207 -856 -15 -584 -691 -484 -706 -676 -235 -197 53 -176 -657 -213 -605 -798 -751 359 -279 -41 -186 -450 -53 -421 -190 -229 -410 -149 -110 -215 -382 -348 -53 139 -140 -412 -473 -47 -535 -172 -29 -195 -425 -115 -188 -278 -266 -419 -201 50 357 160 -29 -99 -398 -460 -448 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YVLSSGRWSVNQEAQ MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 20 w= 15 nsites= 101 E= 5.5e-891 0.000000 0.000000 0.000000 0.000000 0.227723 0.029703 0.019802 0.000000 0.000000 0.019802 0.000000 0.000000 0.000000 0.000000 0.000000 0.009901 0.000000 0.009901 0.000000 0.683168 0.019802 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.118812 0.000000 0.049505 0.009901 0.000000 0.000000 0.000000 0.000000 0.000000 0.029703 0.772277 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.009901 0.009901 0.000000 0.930693 0.000000 0.000000 0.029703 0.000000 0.000000 0.000000 0.000000 0.019802 0.000000 0.000000 0.009901 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.019802 0.000000 0.000000 0.970297 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.009901 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.019802 0.000000 0.000000 0.970297 0.000000 0.000000 0.000000 0.000000 0.039604 0.000000 0.029703 0.049505 0.000000 0.861386 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.009901 0.009901 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.009901 0.000000 0.009901 0.039604 0.000000 0.000000 0.000000 0.000000 0.029703 0.900990 0.009901 0.000000 0.000000 0.000000 0.000000 0.000000 0.009901 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.039604 0.000000 0.000000 0.000000 0.009901 0.019802 0.000000 0.000000 0.009901 0.910891 0.000000 0.029703 0.000000 0.039604 0.029703 0.000000 0.009901 0.000000 0.039604 0.009901 0.009901 0.000000 0.168317 0.029703 0.000000 0.000000 0.435644 0.198020 0.000000 0.000000 0.000000 0.019802 0.000000 0.000000 0.000000 0.000000 0.000000 0.009901 0.079208 0.009901 0.069307 0.009901 0.000000 0.000000 0.019802 0.000000 0.009901 0.029703 0.742574 0.000000 0.000000 0.000000 0.000000 0.108911 0.019802 0.000000 0.089109 0.009901 0.009901 0.009901 0.000000 0.000000 0.673267 0.000000 0.000000 0.000000 0.049505 0.019802 0.009901 0.000000 0.000000 0.000000 0.000000 0.000000 0.029703 0.000000 0.009901 0.059406 0.000000 0.039604 0.009901 0.000000 0.049505 0.049505 0.663366 0.059406 0.019802 0.009901 0.000000 0.000000 0.000000 0.009901 0.000000 0.425743 0.415842 0.000000 0.049505 0.000000 0.000000 0.000000 0.000000 0.000000 0.009901 0.009901 0.059406 0.009901 0.000000 0.009901 0.000000 0.000000 0.000000 0.534653 0.000000 0.069307 0.029703 0.000000 0.039604 0.000000 0.009901 0.009901 0.000000 0.009901 0.029703 0.009901 0.000000 0.000000 0.099010 0.148515 0.009901 0.000000 0.000000 0.029703 0.000000 0.019802 0.079208 0.009901 0.000000 0.009901 0.009901 0.000000 0.009901 0.000000 0.009901 0.059406 0.524752 0.108911 0.108911 0.019802 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YVLSSGRWSVNQEAQ MEME-2 regular expression -------------------------------------------------------------------------------- [YF]VLSSGRWSVNQ[DE]AQ -------------------------------------------------------------------------------- Time 95.29 secs. ******************************************************************************** ******************************************************************************** MOTIF KKRKLQAEQLGLPLP MEME-3 width = 15 sites = 107 llr = 2800 E-value = 1.1e-760 ******************************************************************************** -------------------------------------------------------------------------------- Motif KKRKLQAEQLGLPLP MEME-3 Description -------------------------------------------------------------------------------- Simplified A ::::::4:::::::: pos.-specific C ::::::::::::::: probability D ::::::12::3:::: matrix E :::::1:71:2:::: F ::::1::::1::::: G ::::::1:::4:::: H ::::::::1:::::: I :::::::::::::1: K 9a:a::::::::::: L ::::71::26:7131 M :::::::::::1::: N ::::::::::::::: P :::::1::::::716 Q :::::6::5:::::: R 1:a::1:::::::1: S ::::1:1::2::112 T ::::::1::::1:1: V :::::::::::::1: W ::::::::::::::: Y ::::::1:::::::: bits 6.8 6.1 5.4 4.8 * Relative 4.1 *** Entropy 3.4 **** (37.7 bits) 2.7 **** * * 2.0 ****** ****** * 1.4 *************** 0.7 *************** 0.0 --------------- Multilevel KKRKLQAEQLGLPLP consensus L D sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KKRKLQAEQLGLPLP MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- --------------- XP_024189435.1 29 1.14e-18 FPVIEVGRTI KKRKLQAEQLGLPVP KHKCWDLNFP GAV76568.1 29 1.66e-18 APNTNIVDFN KKRKLQAEQLGLPTP KHKFSNRSLL XP_004302767.1 27 1.66e-18 YPVIEVGKTI KKRKLQAEQLGLPTP KHKCWDLNFP XP_008240727.1 24 1.96e-18 SHVMSVLKRI KKRKFQAEQLGLPIP KHKCWERIFP RVW33794.1 34 6.45e-18 ELNTNIMDLN KKRKLQAELLDLPLP KHKCCGRSFS PHT70537.1 43 9.96e-18 LLPTSLAYLN KKRKFQAEQLGMPLP KHVCSYHSSA XP_006349495.1 31 9.96e-18 LLPTSLVYFN KKRKFQAEQLGMPLP KHMCSYQSSA PSS34997.1 29 2.20e-17 VLQSSIVYLN KKRKFQAELLGLPLP KHKCWERSFS XP_023913884.1 29 2.94e-17 AFKNNIISFN KKRKLHAEQLGLPIP KHGCWDHSFA OAY41326.1 6 3.95e-17 MFDVG KKRKLQAEQFGLPFP KHKCWQKIAT XP_021622766.1 6 3.95e-17 MFDVS KKRKLQAEQFGLPFP KHKCWDNHSS XP_017215985.1 29 4.72e-17 VLHASIIIMN KKRKLQVEQLDLPLP KHNCCKKGIT XP_012074964.1 30 5.36e-17 ALNANMFNLS KKRKLQAEQFGLPMP KLKCWDHRLS XP_018806280.1 29 8.57e-17 RLKDNIVNLN KKRKLQAEQLDLPKP KHKFCARSFA XP_019162543.1 30 1.47e-16 VIHASLACLN KKRKLRAEQLGMPLP KHMCADQSFV XP_009798034.1 29 1.47e-16 VLPTSLAYFN KKRKFQAEQLGIPLP KHLCSYQSYA XP_021650240.1 16 1.88e-16 SHSENMFDVS KKRKLQADQFGLPFP KHKCWDNHSS PON90845.1 24 2.18e-16 RRVISVLNTL KKRKLQAEQLGLPTR KQKCWDRAVA GAY47919.1 61 5.02e-16 IRRADVIGLN KKRKLQAEHLGLPIA KLKCSDGSFR TKS09656.1 29 6.40e-16 APNSKLFCLN KKRKLQDEQLGLPIS KHKCWDHRLP RWR86109.1 18 6.40e-16 PFEIISTDWN KKRKLQGEQLGMPSP KHKFRDRCCS XP_002531564.2 30 6.40e-16 ALNGSMFDLN KKRKLQAEQLVLPIS KHKCWDHRII XP_018841755.1 29 8.07e-16 GLENNTVDLN KKRKLQAGQSDLPIP KHKCWDRSFA XP_024028595.1 24 1.64e-15 LRVISVKKTI KKRKLLAEQLGLPIL KHKCRDQAVS PKI43461.1 33 1.64e-15 MFHGSILDLN KKRKLQSELLGLPTP KHTCLGRGSA XP_015896979.1 24 1.84e-15 FRVVDVIRTI KKRKLQAEQLELPMA KHKCWQSSPS XP_027353450.1 29 2.30e-15 MDNLKIIEWK KKRKLQTDQLDLLRP KHKCWLGSFS XP_012442486.1 64 2.58e-15 EKSINIVDLN KKRKLEAEQLGLPLS KHQCWKQSSS OUZ99277.1 16 3.22e-15 EKENPSEINS KKRKLQDEQSDLPSP KHKFREKRSA TKY66008.1 29 3.22e-15 MHNLNIVEWK KKRKLQIDQLDLLRP KHKCWVGSFS PSS23773.1 3 3.59e-15 LN KKRKYQGEQLGLPPP KHYCWDQSLS XP_021289458.1 27 3.59e-15 NGSMNIVDFN KKRKLEAEQLGLPIS KHQCWNRSLP XP_022948410.1 19 4.03e-15 TEINSFYEIS KKRKLPAEHLGLPSP KHKHSNEASP XP_004137783.2 120 4.03e-15 KLRSNPFDLN KKRKLPAEHLGLPSP KHKHCSEEFA XP_022145567.1 29 4.03e-15 KLRNNPFDLN KKRKLPAEHLGLPSP KHKHCSEGFP XP_022846646.1 24 5.01e-15 MKQTSFIDLS KKRKLQDEQLIMPLP KHICSNRSLE XP_028783417.1 29 5.57e-15 FQQTNIVEWN KKRKLQTEQLDLPRQ KHKCWARRFS XP_017416333.1 35 6.94e-15 IDDFNIVEWK KKRKLQSDQLDLLRP KHKCWVGSYS XP_027336786.1 29 1.06e-14 VHETNIAEWN KKRKLQSDELDLPRP KHKCWLGNSS XP_012850185.1 18 1.17e-14 AEINSIDCLS KKRKLQDELLELPLL KHVCWHQNPE PIN04755.1 19 1.17e-14 AEISSVAYLN KKRKFQAELLEMPCP KHVCFGQRLE XP_028773013.1 54 1.17e-14 VRMTHIVEWN KKRKLQIDQLDMLRP KHKCWVRSFP XP_027149457.1 3 1.78e-14 MD RKRKLQAEELGTPPP KLKWPSQGFA XP_011077640.1 72 1.97e-14 AEVNSIAYLN KKRKLQAELQEMPLP KHVCWGHSLE XP_021691173.1 36 1.97e-14 ALSENMFDVS KERKLQAEQFGLPVP KRNCWDHDSS RXI02216.1 39 2.67e-14 FPVMNVISPM KKRKFHEEQLGLPPP KHRCWARVFP RAL39303.1 15 3.61e-14 LLQTSLTNLN KKRKLEAQQFGLPLP KHLCACQTFL XP_028119329.1 29 4.85e-14 VLQSSFVYLN KKRKFQAGQSSLPLP KHKCWDRTSS XP_013448883.1 31 7.17e-14 MHDINIIEWN KKRKLQGFQLDMLRP KHKCRVESFS XP_015960799.1 29 7.17e-14 MYGISFAEFN KKRKLQSDQLDLVRP KHKCWVGSFC XP_022983598.1 28 7.91e-14 KLQTNPFDLN KKRKLPAEHLGLPSS KHKHCNEGFP XP_022742854.1 27 7.91e-14 NKSLNIVDLN KKRKLEAEQLVLPVS KHHCWKQSLS XP_022747248.1 23 1.16e-13 KSLLNIDHLS KKRKLGAELLGLPVS KHQCWKRSLS TKR66562.1 26 1.28e-13 ALNSKCFYLN KKRKARAEQLGLPIS KHKCWDHRFP TEY25303.1 19 1.40e-13 EEIHSIDYLN KKRKLQDELLVMPLW KHACWDYRLV XP_010047842.1 13 1.69e-13 QDDENPSNIN RKRKLQPELLVLPLP KHQCWDQGTI PNX96427.1 14 2.04e-13 MRDINIIEWN KKRKLQGFQLDLIRP KHKCRVESSS TKY63306.1 34 2.04e-13 VHETNIIEWN KKRKLQSDQLDFLRP KHRCWVGNSS XP_004514391.1 31 2.69e-13 MHDINIIEWN KKRKLHGYQLDLLRP KNKCRVENVS XP_027176296.1 13 2.95e-13 ENVICTTETN RKRKLQAEELGTPPS KLKWLSRGFA OMO66336.1 26 3.24e-13 INGSLIVDLN KKRKLEAENLGLPIS KHQCWNRSLE PIN03316.1 19 3.24e-13 TEINGIGYLN KKRKLRNELLEMPLP KHICWGQNTD XP_007134047.1 29 3.54e-13 VHKVNIIEWN KKRKFQSNQLDLLRP KHKCWVGNSS XP_026417177.1 30 4.65e-13 PIYGSSVDLN KKRKLEDDQVDLPSP KHKCGEPASE PKI39361.1 29 5.09e-13 ALYGNISDLN KKRKLEVEQLDLPSA KHKCWDQGCS XP_010937591.1 50 5.56e-13 ELSPSRVELN KKRKLQYELDDLGLP SPKHKFGDRF XP_008803152.1 103 5.56e-13 ELSRSSVELN KKRKLQYELDDLGLP SPKHKFRDRF XP_023544624.1 34 7.26e-13 PWDTESFDVK KKRKLLFEQLSLPTP KLPCWGPSSS XP_010528448.1 33 1.46e-12 VLNMEAVNLS RKRKFQTEQLELLPL PKHVCFDENK OVA17828.1 32 1.73e-12 PVYAGIIDFN KKRKLEDDELGLPQP KHKYRDQSSS XP_020553487.1 19 2.88e-12 AEMNSIAYLN KKRKLHVELLGGPSP KHLCWGKKFE XP_019459351.1 31 3.41e-12 MQNINIVEWR NKRKLQSDQSDLLRP KHKCRVGHLS KFK24705.1 13 4.37e-12 IVTEESPDSS KKRKLRAEESDLLPL PKHFCMEQQQ XP_010558336.1 27 4.75e-12 SHPVADVGSG RKRKLLAEVLELPLR KQVCHKQTSL KFK36656.1 37 8.41e-12 VLNMEAVDVS KKRKFQTDQSELSLL PLSKHVCFDN XP_006410959.1 36 8.41e-12 VLKMEAVEMS KKRKFQTDQSELSLL PLSKHACFDN XP_010543288.1 30 1.72e-11 VVDAGSSDSG RKRKLLDGVLELPLP KHVRLEQTSI XP_006398684.1 32 1.72e-11 IVAEESPDSS KKRKLGAEESDLLPL PKHFCLEQAA EPS60070.1 19 2.01e-11 TQQSRITDKD KKRKCQGELVEIPWP KHVRRCSSED RID43060.1 32 3.73e-11 VAEEESLDLS RKRKLPAEESDLLPL PKHFCLEQQQ XP_010037822.1 27 5.06e-11 IKSRNIVDLS KKRKHLSEHCELPLP KHKCLDGGFD XP_010529822.1 33 5.06e-11 VLNMEAIDLS KKRKLQTDQFDSSPL PKHVCFHDKG XP_008448098.1 48 6.83e-11 SWNTEAIDVK KKRRLLIDQLSLPTS KLPCWGSRSI OEL29447.1 142 7.93e-11 EKVYTINSPL KKRKSQYELVDPRLL SLKYKFRNRL XP_014752653.1 35 8.54e-11 KNLYPIDSPI KKRKSQYELSDTRLS SLKYKFQNRL AAL35819.1 40 1.43e-10 VLKMEEVEMS KKRKFQTDQSDELSL LPLSKHTCFA RLN19347.1 46 1.53e-10 EKIYTMKSPH KKRKSQYELVDPSLL SLKYKFRNRL XP_012832023.1 13 1.65e-10 EDMISSAEFN RKRKIQGEPMETPRP KHVCWDQRAD EEC74952.1 49 1.77e-10 EKFYHIESPH KKRKSQYELSDTRVS SLKYKFRNRL NP_001354359.1 48 2.05e-10 EKVYAISSPS KKRKSQYELSDPKLL PLKCKFRKRL VAI07274.1 47 2.05e-10 KKIYPIDSPI KKRKSQYDLSDTRLS SLKYKFQDRP VDD15356.1 225 2.05e-10 LKMEAVDEVS KKRKFQIDRSELSLL PLSKHACFDK KZV44349.1 19 2.93e-10 TEINRVDLLC KKRKIRREPVGVPLP KHVRWGQVVE XP_021307618.1 75 5.89e-10 EKVYAVNSPH KKRKSQYELSDPKLV PLKCKFRKRL OAO95598.1 32 8.89e-10 IVAVESLDTS KKRKRRAEESYLLPL PKHFCSEQQA XP_022143715.1 31 1.43e-09 PWNTGGFDVK KKRKLLIELEQLSFP TPKLPRWGPT XP_020108001.1 30 2.13e-09 EFSQVGNEVN KKRKLLCELNDSELP VSKHKFRFRD XP_020593816.1 23 3.15e-09 GHSISSVDLN KKRKLQDELDSQEIS SSKQRFRVGT XP_024982170.1 21 4.95e-09 PCGINRKLYM NKRKFHHGSLDLPVS KHACFEKSSN XP_023734875.1 23 4.95e-09 SNEDPSAINR NKRKSQNEDFNLPVS KHTCLEKSVS PIA54706.1 30 5.99e-09 ILHDNSIDLS KKRKLLDKKLSFPIR KYKFGERTPG XP_022039957.1 50 4.53e-08 NNNNNFDACR NKRKFQDEISEELPV AKHTCLCLDI XP_020268040.1 25 1.02e-07 DHSANIIELN KKRKLPCYELENSDS PLLKHRNCDR TEY72131.1 64 1.08e-07 FLYTSIASLK KKRKQQDSQPEKHLA KHVCREKVEG XP_021744044.1 12 1.36e-07 KLVASNLKKR KQLAVAADDLGLPAP KHVCCEVADS XP_021741222.1 12 1.80e-07 KLVGSNLKKR KQLAVAAEDFGLPAP KHVCYEAADE ADE76868.1 28 2.83e-06 NAVVFFSGEL SKKRKLEEQLNLPSA KHNVRLNPGN -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KKRKLQAEQLGLPLP MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- XP_024189435.1 1.1e-18 28_[3]_215 GAV76568.1 1.7e-18 28_[3]_221 XP_004302767.1 1.7e-18 26_[3]_215 XP_008240727.1 2e-18 23_[3]_193 RVW33794.1 6.4e-18 33_[3]_212 PHT70537.1 1e-17 42_[3]_215 XP_006349495.1 1e-17 30_[3]_215 PSS34997.1 2.2e-17 28_[3]_218 XP_023913884.1 2.9e-17 28_[3]_202 OAY41326.1 3.9e-17 5_[3]_175 XP_021622766.1 3.9e-17 5_[3]_217 XP_017215985.1 4.7e-17 28_[3]_210 XP_012074964.1 5.4e-17 29_[3]_213 XP_018806280.1 8.6e-17 28_[3]_202 XP_019162543.1 1.5e-16 29_[3]_200 XP_009798034.1 1.5e-16 28_[3]_216 XP_021650240.1 1.9e-16 15_[3]_219 PON90845.1 2.2e-16 23_[3]_207 GAY47919.1 5e-16 60_[3]_209 TKS09656.1 6.4e-16 28_[3]_218 RWR86109.1 6.4e-16 17_[3]_221 XP_002531564.2 6.4e-16 29_[3]_217 XP_018841755.1 8.1e-16 28_[3]_179 XP_024028595.1 1.6e-15 23_[3]_198 PKI43461.1 1.6e-15 32_[3]_194 XP_015896979.1 1.8e-15 23_[3]_208 XP_027353450.1 2.3e-15 28_[3]_192 XP_012442486.1 2.6e-15 63_[3]_204 OUZ99277.1 3.2e-15 15_[3]_199 TKY66008.1 3.2e-15 28_[3]_183 PSS23773.1 3.6e-15 2_[3]_186 XP_021289458.1 3.6e-15 26_[3]_212 XP_022948410.1 4e-15 18_[3]_196 XP_004137783.2 4e-15 119_[3]_213 XP_022145567.1 4e-15 28_[3]_205 XP_022846646.1 5e-15 23_[3]_207 XP_028783417.1 5.6e-15 28_[3]_164 XP_017416333.1 6.9e-15 34_[3]_183 XP_027336786.1 1.1e-14 28_[3]_210 XP_012850185.1 1.2e-14 17_[3]_172 PIN04755.1 1.2e-14 18_[3]_194 XP_028773013.1 1.2e-14 53_[3]_213 XP_027149457.1 1.8e-14 2_[3]_215 XP_011077640.1 2e-14 71_[3]_199 XP_021691173.1 2e-14 35_[3]_202 RXI02216.1 2.7e-14 38_[3]_204 RAL39303.1 3.6e-14 14_[3]_182 XP_028119329.1 4.8e-14 28_[3]_198 XP_013448883.1 7.2e-14 30_[3]_168 XP_015960799.1 7.2e-14 28_[3]_146 XP_022983598.1 7.9e-14 27_[3]_211 XP_022742854.1 7.9e-14 26_[3]_212 XP_022747248.1 1.2e-13 22_[3]_212 TKR66562.1 1.3e-13 25_[3]_217 TEY25303.1 1.4e-13 18_[3]_210 XP_010047842.1 1.7e-13 12_[3]_216 PNX96427.1 2e-13 13_[3]_187 TKY63306.1 2e-13 33_[3]_214 XP_004514391.1 2.7e-13 30_[3]_193 XP_027176296.1 3e-13 12_[3]_215 OMO66336.1 3.2e-13 25_[3]_209 PIN03316.1 3.2e-13 18_[3]_177 XP_007134047.1 3.5e-13 28_[3]_208 XP_026417177.1 4.7e-13 29_[3]_199 PKI39361.1 5.1e-13 28_[3]_220 XP_010937591.1 5.6e-13 49_[3]_216 XP_008803152.1 5.6e-13 102_[3]_222 XP_023544624.1 7.3e-13 33_[3]_145 XP_010528448.1 1.5e-12 32_[3]_133 OVA17828.1 1.7e-12 31_[3]_222 XP_020553487.1 2.9e-12 18_[3]_211 XP_019459351.1 3.4e-12 30_[3]_193 KFK24705.1 4.4e-12 12_[3]_147 XP_010558336.1 4.8e-12 26_[3]_196 KFK36656.1 8.4e-12 36_[3]_146 XP_006410959.1 8.4e-12 35_[3]_141 XP_010543288.1 1.7e-11 29_[3]_156 XP_006398684.1 1.7e-11 31_[3]_156 EPS60070.1 2e-11 18_[3]_146 RID43060.1 3.7e-11 31_[3]_150 XP_010037822.1 5.1e-11 26_[3]_216 XP_010529822.1 5.1e-11 32_[3]_152 XP_008448098.1 6.8e-11 47_[3]_139 OEL29447.1 7.9e-11 141_[3]_203 XP_014752653.1 8.5e-11 34_[3]_197 AAL35819.1 1.4e-10 39_[3]_148 RLN19347.1 1.5e-10 45_[3]_203 XP_012832023.1 1.7e-10 12_[3]_167 EEC74952.1 1.8e-10 48_[3]_202 NP_001354359.1 2e-10 47_[3]_204 VAI07274.1 2e-10 46_[3]_188 VDD15356.1 2e-10 224_[3]_141 KZV44349.1 2.9e-10 18_[3]_154 XP_021307618.1 5.9e-10 74_[3]_204 OAO95598.1 8.9e-10 31_[3]_155 XP_022143715.1 1.4e-09 30_[3]_124 XP_020108001.1 2.1e-09 29_[3]_202 XP_020593816.1 3.2e-09 22_[3]_187 XP_024982170.1 5e-09 20_[3]_204 XP_023734875.1 5e-09 22_[3]_173 PIA54706.1 6e-09 29_[3]_219 XP_022039957.1 4.5e-08 49_[3]_118 XP_020268040.1 1e-07 24_[3]_135 TEY72131.1 1.1e-07 63_[3]_171 XP_021744044.1 1.4e-07 11_[3]_180 XP_021741222.1 1.8e-07 11_[3]_179 ADE76868.1 2.8e-06 27_[3]_359 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KKRKLQAEQLGLPLP MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF KKRKLQAEQLGLPLP width=15 seqs=107 XP_024189435.1 ( 29) KKRKLQAEQLGLPVP 1 GAV76568.1 ( 29) KKRKLQAEQLGLPTP 1 XP_004302767.1 ( 27) KKRKLQAEQLGLPTP 1 XP_008240727.1 ( 24) KKRKFQAEQLGLPIP 1 RVW33794.1 ( 34) KKRKLQAELLDLPLP 1 PHT70537.1 ( 43) KKRKFQAEQLGMPLP 1 XP_006349495.1 ( 31) KKRKFQAEQLGMPLP 1 PSS34997.1 ( 29) KKRKFQAELLGLPLP 1 XP_023913884.1 ( 29) KKRKLHAEQLGLPIP 1 OAY41326.1 ( 6) KKRKLQAEQFGLPFP 1 XP_021622766.1 ( 6) KKRKLQAEQFGLPFP 1 XP_017215985.1 ( 29) KKRKLQVEQLDLPLP 1 XP_012074964.1 ( 30) KKRKLQAEQFGLPMP 1 XP_018806280.1 ( 29) KKRKLQAEQLDLPKP 1 XP_019162543.1 ( 30) KKRKLRAEQLGMPLP 1 XP_009798034.1 ( 29) KKRKFQAEQLGIPLP 1 XP_021650240.1 ( 16) KKRKLQADQFGLPFP 1 PON90845.1 ( 24) KKRKLQAEQLGLPTR 1 GAY47919.1 ( 61) KKRKLQAEHLGLPIA 1 TKS09656.1 ( 29) KKRKLQDEQLGLPIS 1 RWR86109.1 ( 18) KKRKLQGEQLGMPSP 1 XP_002531564.2 ( 30) KKRKLQAEQLVLPIS 1 XP_018841755.1 ( 29) KKRKLQAGQSDLPIP 1 XP_024028595.1 ( 24) KKRKLLAEQLGLPIL 1 PKI43461.1 ( 33) KKRKLQSELLGLPTP 1 XP_015896979.1 ( 24) KKRKLQAEQLELPMA 1 XP_027353450.1 ( 29) KKRKLQTDQLDLLRP 1 XP_012442486.1 ( 64) KKRKLEAEQLGLPLS 1 OUZ99277.1 ( 16) KKRKLQDEQSDLPSP 1 TKY66008.1 ( 29) KKRKLQIDQLDLLRP 1 PSS23773.1 ( 3) KKRKYQGEQLGLPPP 1 XP_021289458.1 ( 27) KKRKLEAEQLGLPIS 1 XP_022948410.1 ( 19) KKRKLPAEHLGLPSP 1 XP_004137783.2 ( 120) KKRKLPAEHLGLPSP 1 XP_022145567.1 ( 29) KKRKLPAEHLGLPSP 1 XP_022846646.1 ( 24) KKRKLQDEQLIMPLP 1 XP_028783417.1 ( 29) KKRKLQTEQLDLPRQ 1 XP_017416333.1 ( 35) KKRKLQSDQLDLLRP 1 XP_027336786.1 ( 29) KKRKLQSDELDLPRP 1 XP_012850185.1 ( 18) KKRKLQDELLELPLL 1 PIN04755.1 ( 19) KKRKFQAELLEMPCP 1 XP_028773013.1 ( 54) KKRKLQIDQLDMLRP 1 XP_027149457.1 ( 3) RKRKLQAEELGTPPP 1 XP_011077640.1 ( 72) KKRKLQAELQEMPLP 1 XP_021691173.1 ( 36) KERKLQAEQFGLPVP 1 RXI02216.1 ( 39) KKRKFHEEQLGLPPP 1 RAL39303.1 ( 15) KKRKLEAQQFGLPLP 1 XP_028119329.1 ( 29) KKRKFQAGQSSLPLP 1 XP_013448883.1 ( 31) KKRKLQGFQLDMLRP 1 XP_015960799.1 ( 29) KKRKLQSDQLDLVRP 1 XP_022983598.1 ( 28) KKRKLPAEHLGLPSS 1 XP_022742854.1 ( 27) KKRKLEAEQLVLPVS 1 XP_022747248.1 ( 23) KKRKLGAELLGLPVS 1 TKR66562.1 ( 26) KKRKARAEQLGLPIS 1 TEY25303.1 ( 19) KKRKLQDELLVMPLW 1 XP_010047842.1 ( 13) RKRKLQPELLVLPLP 1 PNX96427.1 ( 14) KKRKLQGFQLDLIRP 1 TKY63306.1 ( 34) KKRKLQSDQLDFLRP 1 XP_004514391.1 ( 31) KKRKLHGYQLDLLRP 1 XP_027176296.1 ( 13) RKRKLQAEELGTPPS 1 OMO66336.1 ( 26) KKRKLEAENLGLPIS 1 PIN03316.1 ( 19) KKRKLRNELLEMPLP 1 XP_007134047.1 ( 29) KKRKFQSNQLDLLRP 1 XP_026417177.1 ( 30) KKRKLEDDQVDLPSP 1 PKI39361.1 ( 29) KKRKLEVEQLDLPSA 1 XP_010937591.1 ( 50) KKRKLQYELDDLGLP 1 XP_008803152.1 ( 103) KKRKLQYELDDLGLP 1 XP_023544624.1 ( 34) KKRKLLFEQLSLPTP 1 XP_010528448.1 ( 33) RKRKFQTEQLELLPL 1 OVA17828.1 ( 32) KKRKLEDDELGLPQP 1 XP_020553487.1 ( 19) KKRKLHVELLGGPSP 1 XP_019459351.1 ( 31) NKRKLQSDQSDLLRP 1 KFK24705.1 ( 13) KKRKLRAEESDLLPL 1 XP_010558336.1 ( 27) RKRKLLAEVLELPLR 1 KFK36656.1 ( 37) KKRKFQTDQSELSLL 1 XP_006410959.1 ( 36) KKRKFQTDQSELSLL 1 XP_010543288.1 ( 30) RKRKLLDGVLELPLP 1 XP_006398684.1 ( 32) KKRKLGAEESDLLPL 1 EPS60070.1 ( 19) KKRKCQGELVEIPWP 1 RID43060.1 ( 32) RKRKLPAEESDLLPL 1 XP_010037822.1 ( 27) KKRKHLSEHCELPLP 1 XP_010529822.1 ( 33) KKRKLQTDQFDSSPL 1 XP_008448098.1 ( 48) KKRRLLIDQLSLPTS 1 OEL29447.1 ( 142) KKRKSQYELVDPRLL 1 XP_014752653.1 ( 35) KKRKSQYELSDTRLS 1 AAL35819.1 ( 40) KKRKFQTDQSDELSL 1 RLN19347.1 ( 46) KKRKSQYELVDPSLL 1 XP_012832023.1 ( 13) RKRKIQGEPMETPRP 1 EEC74952.1 ( 49) KKRKSQYELSDTRVS 1 NP_001354359.1 ( 48) KKRKSQYELSDPKLL 1 VAI07274.1 ( 47) KKRKSQYDLSDTRLS 1 VDD15356.1 ( 225) KKRKFQIDRSELSLL 1 KZV44349.1 ( 19) KKRKIRREPVGVPLP 1 XP_021307618.1 ( 75) KKRKSQYELSDPKLV 1 OAO95598.1 ( 32) KKRKRRAEESYLLPL 1 XP_022143715.1 ( 31) KKRKLLIELEQLSFP 1 XP_020108001.1 ( 30) KKRKLLCELNDSELP 1 XP_020593816.1 ( 23) KKRKLQDELDSQEIS 1 XP_024982170.1 ( 21) NKRKFHHGSLDLPVS 1 XP_023734875.1 ( 23) NKRKSQNEDFNLPVS 1 PIA54706.1 ( 30) KKRKLLDKKLSFPIR 1 XP_022039957.1 ( 50) NKRKFQDEISEELPV 1 XP_020268040.1 ( 25) KKRKLPCYELENSDS 1 TEY72131.1 ( 64) KKRKQQDSQPEKHLA 1 XP_021744044.1 ( 12) KQLAVAADDLGLPAP 1 XP_021741222.1 ( 12) KQLAVAAEDFGLPAP 1 ADE76868.1 ( 28) SKKRKLEEQLNLPSA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KKRKLQAEQLGLPLP MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 20 w= 15 n= 26933 bayes= 7.87554 E= 1.1e-760 -373 -461 -601 -570 -606 -509 -447 -430 393 -528 -482 -139 -496 -438 76 -427 -425 -479 -429 -543 -455 -558 -673 -352 -689 -580 -487 -520 402 -591 -553 -521 -578 -134 -153 -657 -494 -548 -513 -607 -390 -402 -592 -614 -562 -479 -311 -457 -176 -250 -492 -452 -435 -336 475 -559 -444 -512 -340 -510 -195 -445 -590 -565 -592 -498 -443 -415 399 -518 -471 -444 -483 -444 -13 -588 -414 -468 -415 -533 -221 -135 -681 -621 162 -589 -167 -76 -273 316 -200 -592 -516 -220 -194 -111 -425 -97 -402 -192 -146 -429 -505 -77 -510 -206 57 -414 -365 -31 -285 -370 -14 408 19 -484 -367 -396 -344 -492 330 -24 35 -230 -209 14 -148 4 -357 -424 -388 -159 -214 -360 -165 -85 36 -52 -429 110 -492 -803 124 281 -112 -53 -540 -732 -244 -746 -723 -223 -614 -192 -563 -358 -541 -653 -775 -85 -297 -540 -134 -23 -523 -440 106 -198 -185 142 -420 -211 -108 360 -137 -317 -335 -114 -464 -463 -397 -131 -168 -348 86 -580 -504 -221 -532 305 -99 -271 -221 -217 -439 7 -416 7 -404 -458 -500 -750 214 69 -780 275 -507 -210 -512 -749 -729 -134 -614 -196 -545 -146 -520 -23 -739 -181 -415 -463 -679 -265 -108 -274 -505 -76 -275 318 165 -277 -41 -221 -430 -302 -2 -158 -401 -463 -318 -555 -573 -244 -582 -159 -153 -210 -166 77 -550 -561 408 -466 -2 -111 -430 -212 -581 -623 -109 -107 -299 -652 -6 -540 -504 150 -252 195 -42 -571 130 -205 185 -39 30 70 7 -442 -2 -554 -574 -573 -582 -514 -510 -513 -484 68 -549 -562 391 -208 -42 20 -430 -125 -10 -623 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KKRKLQAEQLGLPLP MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 20 w= 15 nsites= 107 E= 1.1e-760 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.878505 0.000000 0.000000 0.037383 0.000000 0.000000 0.074766 0.009346 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.009346 0.000000 0.000000 0.000000 0.000000 0.971963 0.000000 0.000000 0.000000 0.000000 0.018692 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.009346 0.018692 0.000000 0.000000 0.000000 0.000000 0.971963 0.000000 0.000000 0.000000 0.000000 0.000000 0.018692 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.962617 0.000000 0.000000 0.000000 0.000000 0.000000 0.018692 0.000000 0.000000 0.000000 0.000000 0.000000 0.009346 0.009346 0.000000 0.000000 0.149533 0.000000 0.009346 0.018692 0.009346 0.672897 0.000000 0.000000 0.000000 0.009346 0.009346 0.074766 0.000000 0.018692 0.000000 0.009346 0.018692 0.000000 0.000000 0.074766 0.000000 0.018692 0.046729 0.000000 0.000000 0.093458 0.000000 0.000000 0.056075 0.635514 0.056075 0.000000 0.000000 0.000000 0.000000 0.000000 0.429907 0.018692 0.112150 0.018692 0.009346 0.065421 0.009346 0.046729 0.000000 0.000000 0.000000 0.018692 0.009346 0.000000 0.009346 0.074766 0.065421 0.028037 0.000000 0.084112 0.000000 0.000000 0.177570 0.710280 0.018692 0.037383 0.000000 0.000000 0.009346 0.000000 0.000000 0.009346 0.000000 0.009346 0.000000 0.009346 0.000000 0.000000 0.000000 0.018692 0.000000 0.000000 0.028037 0.084112 0.000000 0.000000 0.056075 0.009346 0.009346 0.224299 0.000000 0.009346 0.018692 0.523364 0.009346 0.009346 0.000000 0.018692 0.000000 0.000000 0.000000 0.009346 0.028037 0.009346 0.084112 0.000000 0.000000 0.000000 0.000000 0.616822 0.009346 0.009346 0.009346 0.009346 0.000000 0.168224 0.000000 0.046729 0.000000 0.000000 0.000000 0.000000 0.336449 0.158879 0.000000 0.373832 0.000000 0.009346 0.000000 0.000000 0.000000 0.018692 0.000000 0.009346 0.000000 0.046729 0.000000 0.037383 0.000000 0.009346 0.000000 0.000000 0.000000 0.018692 0.018692 0.009346 0.000000 0.018692 0.009346 0.682243 0.102804 0.009346 0.037383 0.009346 0.000000 0.018692 0.056075 0.009346 0.000000 0.000000 0.000000 0.000000 0.000000 0.018692 0.000000 0.018692 0.009346 0.009346 0.018692 0.149533 0.000000 0.000000 0.663551 0.000000 0.037383 0.065421 0.000000 0.009346 0.000000 0.000000 0.018692 0.009346 0.009346 0.000000 0.037383 0.000000 0.000000 0.112150 0.009346 0.308411 0.018692 0.000000 0.102804 0.009346 0.130841 0.102804 0.056075 0.065421 0.009346 0.000000 0.046729 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.140187 0.000000 0.000000 0.579439 0.009346 0.028037 0.168224 0.000000 0.018692 0.009346 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KKRKLQAEQLGLPLP MEME-3 regular expression -------------------------------------------------------------------------------- KKRKLQAE[QL]L[GD]LPLP -------------------------------------------------------------------------------- Time 138.15 secs. ******************************************************************************** ******************************************************************************** MOTIF PESAKDSNSFAEDSD MEME-4 width = 15 sites = 84 llr = 1972 E-value = 1.1e-451 ******************************************************************************** -------------------------------------------------------------------------------- Motif PESAKDSNSFAEDSD MEME-4 Description -------------------------------------------------------------------------------- Simplified A :::5::::::2::1: pos.-specific C ::::::::::::::: probability D :1:::8:::::17:8 matrix E 17:11::::::51:: F :::::::::8::::: G :1:1:2::::131:: H ::::::::::1:::: I :::::::::12:::: K ::::7:::::::::: L 1::::::::1::::: M ::::::::::::::: N ::::1::9::::::1 P 4:::::::::::::: Q 1:::1:::::::::: R ::::::::::::::: S ::a:::a:9:2::6: T 1::1::::::1:::: V 1::1::::::1:::: W ::::::::::::::: Y :::::::::::::1: bits 6.8 6.1 5.4 4.8 Relative 4.1 Entropy 3.4 * * * (33.9 bits) 2.7 * ***** 2.0 ********* * * 1.4 *************** 0.7 *************** 0.0 --------------- Multilevel PESAKDSNSFXEDSD consensus G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif PESAKDSNSFAEDSD MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- --------------- XP_012074964.1 86 6.47e-18 ERHEIDDGSD PESAKDSNSFIGDSD SATSLYYDSK XP_013448883.1 91 2.59e-17 DVAFLDDRSE PESAKDSNSFIEDSD TSMSINEEAK XP_004514391.1 91 2.59e-17 DASSAEDRSE PESAKDSNSFIEDSD TSMSVNEEAK TKR66562.1 86 5.95e-17 ERQAIDEGSD PESAKDSNSFVEDSD FAMSVDGEAK XP_015960799.1 89 2.02e-16 DAAFLDERSE PESAKDSNSFMEDSD TAISVNKEAK XP_017416333.1 85 2.02e-16 IHNHTGERSE PESAKDSNSFMEDSD TAVSVNKEAN XP_021622766.1 66 1.04e-15 GRQAIEDGSD LESAKDSNSFVGDSD HVMSVYGEAK GAV76568.1 89 1.18e-15 EGGFIDDVSE PESAKDSNSFVDDSD SAMSVYGENK XP_009798034.1 87 1.48e-15 NRRGQDDDSE PESGKDSNSFIGDAD SVTSGEAKIN PNX96427.1 74 1.75e-15 DAAFLDDRSE HESAKDSNSFIEDSD TSMSVNDDAK XP_022742854.1 84 2.51e-15 KGGAVYDVSE TGSAKDSNSFAEDSD SAISVHAEVK XP_010037822.1 87 3.04e-15 EGGCNHDESQ PESAKGSNSFSEDSD TATSAYGGFN TKY66008.1 79 7.03e-15 MHNHSVERSE PESVKDSNSFIEDCD TAMSVNEEAK TKS09656.1 89 9.30e-15 ERRAIDEGSD PESPKDSNSFVGDSD SAMSVSGEAK XP_027336786.1 85 1.09e-14 EDRTGADSSE PESAKDSNSFTEDSN TAMSVNEEGK XP_021691173.1 96 1.27e-14 ERQSIEDGSD LESGKDSNSFVGDSD CVMSVCGGMF XP_022983598.1 88 1.68e-14 NVLRFDDGSS PESAKDSNSFCEESD SATSVFHGAK XP_027353450.1 89 2.21e-14 DAAFIDDGSQ PESAKDSNSFIDDFD TAMSVNEEAK XP_002531564.2 90 2.53e-14 ERQAIEDVSD PESAKDSNSFVGDSE SIMSVHGEAK XP_012442486.1 121 3.35e-14 KTWAVCDVLE TGSAKDSNSFADDSD TAISVHVDAK XP_022747248.1 80 9.71e-14 KGGAVYDISE TGSAKDSNSFAKDSD SAMSVHAEAK XP_018841755.1 89 1.11e-13 ERAAMDYEAE PESGKDSNSFGGDSN SATSSYDEAK PKI39361.1 94 2.11e-13 RSSYEEPESQ FESAKGSNSFTEDAD SEMSVHDETS XP_023913884.1 90 2.71e-13 GATMVNNELE PESGEGSNSFAEDSD SAMSIYDEAR XP_028773013.1 114 3.05e-13 GALVHDDRPS PVSAEDSNSFAEDSD ASMSVYEEVR PON90845.1 78 3.45e-13 KGLAMDDRSE PESMKDSNSFAEVSD SATSAYNGAK XP_022846646.1 71 3.91e-13 NGLAREYETY TESAKDRNSFTRDSD SVNSISGEAK XP_021650240.1 76 3.91e-13 ARHAMEDVSD LESAEDSNSFVGDCD SAMSVYGEGE XP_023734875.1 63 4.42e-13 SDISHSRFNQ TESAKDSNNFFEDAD SVMSVYNDSE XP_021289458.1 84 4.97e-13 KGGAAYDVSE TGSAEDSNSFSEDSD YAMSVHYEAK XP_020553487.1 70 5.59e-13 IILARGGESD PESAKDSCSFHGDVD SIMSPCDDAK XP_008240727.1 85 5.59e-13 EGVILDGGSE SESGKGSNSFAGDSD SATSVYVEAK XP_012850185.1 58 7.91e-13 NNAESDESFD RESAKDSNSFHCDPD SIMSTDYDDE RWR86109.1 79 7.91e-13 NGGAGDRIEG CESVKDSNSFIEESD TATMPVDSED XP_010256878.1 87 8.89e-13 VRGLAKNGSE QESTKDSNSFVGESD LDISPYTDTE XP_015896979.1 84 1.40e-12 EEHVLEDRSE HDSGKDSNSFFGDSD SPTSIYVEAK OMO66336.1 84 1.57e-12 GGASNYDVSE TGSAKDSNSFGEDSY SLHAEAKFGT XP_028119329.1 87 1.76e-12 VVGARDSESE LESAQDSNSFGGNSD SAMSISGEAK XP_024982170.1 82 2.19e-12 NSHSIDDQIE QGSEKDSNSFSEDAD SVMSVSIDSK XP_024189435.1 91 2.19e-12 EGAFLNDGSG PGSGKGSNSFAGDYC DSAMSVYSEA RVW33794.1 94 2.19e-12 NGETIDDGSE PDSAKDSNSLAGYSD SVISVYGEAK XP_019459351.1 91 5.22e-12 DTTAINVRSE FESAKDNNSFIEESD TSMSVNEEAK XP_004137783.2 180 6.45e-12 NVLCFDEVSR PESVKDSNSLSEESD SATSVFHGAK XP_027176296.1 67 9.79e-12 NGMSTAEESE QESANDSNSIAADAD SSISVSNETE XP_010047842.1 71 1.33e-11 DVSDNNDGTR PESEKDSYSFVEYSD STMSLYGMDN XP_004302767.1 89 1.33e-11 EGGVLNDGSG LGSGKGSNSFAGDYC DSAISVYREV XP_022948410.1 79 1.63e-11 NVICIDEGLT PESVKDSNSFSDESN SATSVFCGAK XP_027149457.1 57 1.80e-11 SGISTAEESE QESAKDSNSVSADAD SSISVSSEAE XP_006349495.1 89 1.99e-11 AARGQEDDSE LESENGSNSFCEDAD SVTSHEAKLD XP_018806280.1 89 4.80e-11 EGAAMDDESE PESAKDSSSFGVESD PAMSPYATEN PIA54706.1 92 5.81e-11 TVHHESKSTL PASVIDSNSFAEESD CAMSQYTEVK XP_011077640.1 123 7.72e-11 NNVVRGGESD TESARDSNSFHCNED SIMSIDYESK XP_020593816.1 77 8.48e-11 REIHNEFEQP EESEKDSNTFTGAYD NSMSSNENFI PHT70537.1 101 1.02e-10 AARVQDDDSE LESENGSNCFSGDAD SVTSHEAKIH XP_024028595.1 82 1.02e-10 KVLAMDGGSE LESMKDSNSYTEDSN SSTSIYGEAK RXI02216.1 100 1.35e-10 DGASLDDRSE PESGGGSNSFARDSG YATSVYGDSK XP_028783417.1 66 1.48e-10 NGSTSDDISE PKSSRGSNSFGEDSD TAISVNEEGK PSS34997.1 89 1.48e-10 VGGANDYESD RESAKDSNSLGGYMD SATSVSEDKI PIN04755.1 70 1.62e-10 AMYARGCESN PESPKDSCSFHSDPD SVLSLHEDAT XP_021744044.1 59 1.77e-10 EEDVEVLDML VESTQDSNSFAGGSH SSTEVIIDAG PIN03316.1 65 1.94e-10 KKLESENESD QGSAKDSNSFHSNKD SIMHIDNESN XP_017215985.1 88 3.03e-10 HQEEKESESE VDSGNGSNSLVEDYD SVMSESYGTK XP_022145567.1 89 3.03e-10 NVMCFGKGSR PGSSKDSNSLSEEAD SATSVFRGAK XP_021741222.1 57 3.62e-10 EEGAEFLNML VESTQDSNSFPGGSQ SSTEVVFEAG TKY63306.1 90 3.62e-10 KGRADADSSE SESVKDINSFSEDSI TVNSVNEEGK RAL39303.1 57 4.31e-10 EDIPESEHET TESGEDSNTITEDFD SAMSIETKPS XP_019162543.1 70 4.70e-10 LVNNQDNELE TQSGKGSNGFIEDID CVMSGEAKVD XP_008803152.1 163 6.63e-10 REIRDGPEQP EDSDNDSNSFIEDYA EAEGYVTAMA XP_020268040.1 80 1.01e-09 IDGGIDNSLE IESENDSISFIGVSD NKITSEVDIK PKI43461.1 89 1.01e-09 KATYEEIGSG LESADGSNSFMEGSV SSTMSVSAKL XP_021856950.1 60 1.10e-09 EEDVHVFDTL AESTQDSNSIPGDSQ SSAEVIFDAG OUZ99277.1 59 2.51e-09 PEDVGLEVKP LNSAEDSNSFVGENN SAISLYPADM XP_022039957.1 77 2.95e-09 HTCLCLDISS SSSAKDSNSFSDDAP PSTSSSVNWC XP_010528448.1 68 2.95e-09 NKNSSDPSPE VESVKDSNSFATAEG SDYSTLSVNS XP_010529822.1 81 6.49e-09 SNNSSDQCSE IESVKDSNSFTMAEA SASSVSSGPM RWW70318.1 12 7.01e-09 VARGLKDGSE GDSYNDSNSISEGYD TTMTLDLDDE XP_010937591.1 109 8.17e-09 IEIRDGLEQL EDSDDDSNSSIEDYD QTEGYVTAMA PWA88889.1 16 1.11e-08 QACLKCQCSQ GEGEGDSNSISEDAD SVMSVAINDQ PSS23773.1 64 1.20e-08 VGEEIYDESK LDSAKDRDNFGGGTD TSISSSNRPS XP_010678090.1 76 1.39e-08 VGHVEVVDTL VESTQDSNNIPADSQ SSTEVIFDAS XP_007134047.1 85 1.50e-08 KGRRDAESSE ANSVKDSNSLSQDSI TAMSVNEEGK XP_018681881.1 10 2.02e-08 MRDESEEPG EESYNDSHSISEGYD ATMTLDLDDE XP_020108001.1 89 1.55e-07 KEIMRDGPEE EESDRDSIISIEDYD SALQANFKGS TEY25303.1 70 1.66e-07 NISARGVESG PDSASNSYCFPSDTD MSMSSHDDAK -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif PESAKDSNSFAEDSD MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- XP_012074964.1 6.5e-18 85_[4]_157 XP_013448883.1 2.6e-17 90_[4]_108 XP_004514391.1 2.6e-17 90_[4]_133 TKR66562.1 6e-17 85_[4]_157 XP_015960799.1 2e-16 88_[4]_86 XP_017416333.1 2e-16 84_[4]_133 XP_021622766.1 1e-15 65_[4]_157 GAV76568.1 1.2e-15 88_[4]_161 XP_009798034.1 1.5e-15 86_[4]_158 PNX96427.1 1.8e-15 73_[4]_127 XP_022742854.1 2.5e-15 83_[4]_155 XP_010037822.1 3e-15 86_[4]_156 TKY66008.1 7e-15 78_[4]_133 TKS09656.1 9.3e-15 88_[4]_158 XP_027336786.1 1.1e-14 84_[4]_154 XP_021691173.1 1.3e-14 95_[4]_142 XP_022983598.1 1.7e-14 87_[4]_151 XP_027353450.1 2.2e-14 88_[4]_132 XP_002531564.2 2.5e-14 89_[4]_157 XP_012442486.1 3.4e-14 120_[4]_147 XP_022747248.1 9.7e-14 79_[4]_155 XP_018841755.1 1.1e-13 88_[4]_119 PKI39361.1 2.1e-13 93_[4]_155 XP_023913884.1 2.7e-13 89_[4]_141 XP_028773013.1 3.1e-13 113_[4]_153 PON90845.1 3.5e-13 77_[4]_153 XP_022846646.1 3.9e-13 70_[4]_160 XP_021650240.1 3.9e-13 75_[4]_159 XP_023734875.1 4.4e-13 62_[4]_133 XP_021289458.1 5e-13 83_[4]_155 XP_020553487.1 5.6e-13 69_[4]_160 XP_008240727.1 5.6e-13 84_[4]_132 XP_012850185.1 7.9e-13 57_[4]_132 RWR86109.1 7.9e-13 78_[4]_160 XP_010256878.1 8.9e-13 86_[4]_160 XP_015896979.1 1.4e-12 83_[4]_148 OMO66336.1 1.6e-12 83_[4]_151 XP_028119329.1 1.8e-12 86_[4]_140 XP_024982170.1 2.2e-12 81_[4]_143 XP_024189435.1 2.2e-12 90_[4]_153 RVW33794.1 2.2e-12 93_[4]_152 XP_019459351.1 5.2e-12 90_[4]_133 XP_004137783.2 6.5e-12 179_[4]_153 XP_027176296.1 9.8e-12 66_[4]_161 XP_010047842.1 1.3e-11 70_[4]_158 XP_004302767.1 1.3e-11 88_[4]_153 XP_022948410.1 1.6e-11 78_[4]_136 XP_027149457.1 1.8e-11 56_[4]_161 XP_006349495.1 2e-11 88_[4]_157 XP_018806280.1 4.8e-11 88_[4]_142 PIA54706.1 5.8e-11 91_[4]_157 XP_011077640.1 7.7e-11 122_[4]_148 XP_020593816.1 8.5e-11 76_[4]_133 PHT70537.1 1e-10 100_[4]_157 XP_024028595.1 1e-10 81_[4]_140 RXI02216.1 1.3e-10 99_[4]_143 XP_028783417.1 1.5e-10 65_[4]_127 PSS34997.1 1.5e-10 88_[4]_158 PIN04755.1 1.6e-10 69_[4]_143 XP_021744044.1 1.8e-10 58_[4]_133 PIN03316.1 1.9e-10 64_[4]_131 XP_017215985.1 3e-10 87_[4]_151 XP_022145567.1 3e-10 88_[4]_145 XP_021741222.1 3.6e-10 56_[4]_134 TKY63306.1 3.6e-10 89_[4]_158 RAL39303.1 4.3e-10 56_[4]_140 XP_019162543.1 4.7e-10 69_[4]_160 XP_008803152.1 6.6e-10 162_[4]_162 XP_020268040.1 1e-09 79_[4]_80 PKI43461.1 1e-09 88_[4]_138 XP_021856950.1 1.1e-09 59_[4]_130 OUZ99277.1 2.5e-09 58_[4]_156 XP_022039957.1 2.9e-09 76_[4]_91 XP_010528448.1 2.9e-09 67_[4]_98 XP_010529822.1 6.5e-09 80_[4]_104 RWW70318.1 7e-09 11_[4]_119 XP_010937591.1 8.2e-09 108_[4]_157 PWA88889.1 1.1e-08 15_[4]_108 PSS23773.1 1.2e-08 63_[4]_125 XP_010678090.1 1.4e-08 75_[4]_138 XP_007134047.1 1.5e-08 84_[4]_152 XP_018681881.1 2e-08 9_[4]_128 XP_020108001.1 1.6e-07 88_[4]_143 TEY25303.1 1.7e-07 69_[4]_159 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif PESAKDSNSFAEDSD MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF PESAKDSNSFAEDSD width=15 seqs=84 XP_012074964.1 ( 86) PESAKDSNSFIGDSD 1 XP_013448883.1 ( 91) PESAKDSNSFIEDSD 1 XP_004514391.1 ( 91) PESAKDSNSFIEDSD 1 TKR66562.1 ( 86) PESAKDSNSFVEDSD 1 XP_015960799.1 ( 89) PESAKDSNSFMEDSD 1 XP_017416333.1 ( 85) PESAKDSNSFMEDSD 1 XP_021622766.1 ( 66) LESAKDSNSFVGDSD 1 GAV76568.1 ( 89) PESAKDSNSFVDDSD 1 XP_009798034.1 ( 87) PESGKDSNSFIGDAD 1 PNX96427.1 ( 74) HESAKDSNSFIEDSD 1 XP_022742854.1 ( 84) TGSAKDSNSFAEDSD 1 XP_010037822.1 ( 87) PESAKGSNSFSEDSD 1 TKY66008.1 ( 79) PESVKDSNSFIEDCD 1 TKS09656.1 ( 89) PESPKDSNSFVGDSD 1 XP_027336786.1 ( 85) PESAKDSNSFTEDSN 1 XP_021691173.1 ( 96) LESGKDSNSFVGDSD 1 XP_022983598.1 ( 88) PESAKDSNSFCEESD 1 XP_027353450.1 ( 89) PESAKDSNSFIDDFD 1 XP_002531564.2 ( 90) PESAKDSNSFVGDSE 1 XP_012442486.1 ( 121) TGSAKDSNSFADDSD 1 XP_022747248.1 ( 80) TGSAKDSNSFAKDSD 1 XP_018841755.1 ( 89) PESGKDSNSFGGDSN 1 PKI39361.1 ( 94) FESAKGSNSFTEDAD 1 XP_023913884.1 ( 90) PESGEGSNSFAEDSD 1 XP_028773013.1 ( 114) PVSAEDSNSFAEDSD 1 PON90845.1 ( 78) PESMKDSNSFAEVSD 1 XP_022846646.1 ( 71) TESAKDRNSFTRDSD 1 XP_021650240.1 ( 76) LESAEDSNSFVGDCD 1 XP_023734875.1 ( 63) TESAKDSNNFFEDAD 1 XP_021289458.1 ( 84) TGSAEDSNSFSEDSD 1 XP_020553487.1 ( 70) PESAKDSCSFHGDVD 1 XP_008240727.1 ( 85) SESGKGSNSFAGDSD 1 XP_012850185.1 ( 58) RESAKDSNSFHCDPD 1 RWR86109.1 ( 79) CESVKDSNSFIEESD 1 XP_010256878.1 ( 87) QESTKDSNSFVGESD 1 XP_015896979.1 ( 84) HDSGKDSNSFFGDSD 1 OMO66336.1 ( 84) TGSAKDSNSFGEDSY 1 XP_028119329.1 ( 87) LESAQDSNSFGGNSD 1 XP_024982170.1 ( 82) QGSEKDSNSFSEDAD 1 XP_024189435.1 ( 91) PGSGKGSNSFAGDYC 1 RVW33794.1 ( 94) PDSAKDSNSLAGYSD 1 XP_019459351.1 ( 91) FESAKDNNSFIEESD 1 XP_004137783.2 ( 180) PESVKDSNSLSEESD 1 XP_027176296.1 ( 67) QESANDSNSIAADAD 1 XP_010047842.1 ( 71) PESEKDSYSFVEYSD 1 XP_004302767.1 ( 89) LGSGKGSNSFAGDYC 1 XP_022948410.1 ( 79) PESVKDSNSFSDESN 1 XP_027149457.1 ( 57) QESAKDSNSVSADAD 1 XP_006349495.1 ( 89) LESENGSNSFCEDAD 1 XP_018806280.1 ( 89) PESAKDSSSFGVESD 1 PIA54706.1 ( 92) PASVIDSNSFAEESD 1 XP_011077640.1 ( 123) TESARDSNSFHCNED 1 XP_020593816.1 ( 77) EESEKDSNTFTGAYD 1 PHT70537.1 ( 101) LESENGSNCFSGDAD 1 XP_024028595.1 ( 82) LESMKDSNSYTEDSN 1 RXI02216.1 ( 100) PESGGGSNSFARDSG 1 XP_028783417.1 ( 66) PKSSRGSNSFGEDSD 1 PSS34997.1 ( 89) RESAKDSNSLGGYMD 1 PIN04755.1 ( 70) PESPKDSCSFHSDPD 1 XP_021744044.1 ( 59) VESTQDSNSFAGGSH 1 PIN03316.1 ( 65) QGSAKDSNSFHSNKD 1 XP_017215985.1 ( 88) VDSGNGSNSLVEDYD 1 XP_022145567.1 ( 89) PGSSKDSNSLSEEAD 1 XP_021741222.1 ( 57) VESTQDSNSFPGGSQ 1 TKY63306.1 ( 90) SESVKDINSFSEDSI 1 RAL39303.1 ( 57) TESGEDSNTITEDFD 1 XP_019162543.1 ( 70) TQSGKGSNGFIEDID 1 XP_008803152.1 ( 163) EDSDNDSNSFIEDYA 1 XP_020268040.1 ( 80) IESENDSISFIGVSD 1 PKI43461.1 ( 89) LESADGSNSFMEGSV 1 XP_021856950.1 ( 60) AESTQDSNSIPGDSQ 1 OUZ99277.1 ( 59) LNSAEDSNSFVGENN 1 XP_022039957.1 ( 77) SSSAKDSNSFSDDAP 1 XP_010528448.1 ( 68) VESVKDSNSFATAEG 1 XP_010529822.1 ( 81) IESVKDSNSFTMAEA 1 RWW70318.1 ( 12) GDSYNDSNSISEGYD 1 XP_010937591.1 ( 109) EDSDDDSNSSIEDYD 1 PWA88889.1 ( 16) GEGEGDSNSISEDAD 1 PSS23773.1 ( 64) LDSAKDRDNFGGGTD 1 XP_010678090.1 ( 76) VESTQDSNNIPADSQ 1 XP_007134047.1 ( 85) ANSVKDSNSLSQDSI 1 XP_018681881.1 ( 10) EESYNDSHSISEGYD 1 XP_020108001.1 ( 89) EESDRDSIISIEDYD 1 TEY25303.1 ( 70) PDSASNSYCFPSDTD 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif PESAKDSNSFAEDSD MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 20 w= 15 n= 26933 bayes= 7.9351 E= 1.1e-451 -74 -80 -502 -75 -70 -116 -13 -53 -371 72 -330 -435 317 49 -48 -180 131 53 -405 -421 -177 -884 38 280 -833 109 -562 -662 -208 -678 -648 -120 -568 -151 -527 -334 -528 -182 -774 -729 -556 -716 -940 -1026 -910 -213 -862 -920 -953 -919 -923 -881 -787 -885 -835 291 -710 -780 -807 -914 346 -275 -130 -52 -431 112 -405 -347 -366 -388 -41 -422 -101 -367 -335 -202 17 110 -398 -73 -381 -612 -154 -45 -614 -114 -399 -171 346 -545 -511 76 -520 55 18 -312 -405 -489 -537 -531 -579 -741 345 -632 -809 151 -539 -843 -602 -847 -859 -188 -671 -591 -617 -607 -567 -785 -753 -709 -357 -534 -597 -711 -723 -493 -604 -175 -576 -736 -699 -206 -622 -603 -54 283 -421 -582 -678 -687 -363 -83 -252 -534 -427 -380 -93 -147 -372 -449 -408 398 -415 -325 -344 -282 -282 -369 -325 -141 -236 -13 -510 -582 -475 -222 -455 -195 -430 -490 -435 -83 -425 -454 -365 268 28 -440 -435 -466 -351 -332 -568 -582 438 -506 -473 29 -521 -53 -294 -530 -451 -526 -475 -301 -449 -184 -202 -83 188 18 -675 -623 -64 56 114 204 -523 -305 43 -540 19 -490 -451 28 84 162 -381 -409 -22 9 -33 212 -491 235 -320 -431 -149 -443 -113 -336 -413 -122 -33 -170 -147 -162 -442 -428 -84 -499 330 -15 -525 -18 -369 -471 -467 -528 -509 -68 -522 -425 -425 -499 -432 -134 -449 -49 120 -7 -487 -172 -97 -420 -411 -163 -215 -396 -129 -196 -99 -394 -336 216 10 -167 -400 133 -154 -76 343 -202 -483 -189 -166 -157 -455 -486 -467 -33 -252 -108 -395 -484 -412 -235 -405 -218 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif PESAKDSNSFAEDSD MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 20 w= 15 nsites= 84 E= 1.1e-451 0.023810 0.011905 0.000000 0.059524 0.023810 0.023810 0.023810 0.023810 0.000000 0.130952 0.000000 0.000000 0.380952 0.059524 0.023810 0.035714 0.119048 0.059524 0.000000 0.000000 0.011905 0.000000 0.095238 0.702381 0.000000 0.119048 0.000000 0.000000 0.011905 0.000000 0.000000 0.023810 0.000000 0.011905 0.000000 0.011905 0.000000 0.011905 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.011905 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.988095 0.000000 0.000000 0.000000 0.000000 0.476190 0.000000 0.035714 0.083333 0.000000 0.142857 0.000000 0.000000 0.000000 0.000000 0.023810 0.000000 0.023810 0.000000 0.000000 0.023810 0.059524 0.107143 0.000000 0.023810 0.000000 0.000000 0.023810 0.071429 0.000000 0.023810 0.000000 0.011905 0.666667 0.000000 0.000000 0.095238 0.000000 0.059524 0.035714 0.011905 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.833333 0.000000 0.000000 0.154762 0.000000 0.000000 0.000000 0.000000 0.000000 0.011905 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.011905 0.000000 0.000000 0.000000 0.011905 0.000000 0.000000 0.023810 0.952381 0.000000 0.000000 0.000000 0.000000 0.000000 0.023810 0.011905 0.000000 0.000000 0.000000 0.011905 0.023810 0.000000 0.000000 0.000000 0.892857 0.000000 0.000000 0.000000 0.011905 0.000000 0.000000 0.000000 0.023810 0.000000 0.023810 0.000000 0.000000 0.000000 0.011905 0.000000 0.011905 0.000000 0.000000 0.000000 0.035714 0.000000 0.000000 0.000000 0.892857 0.023810 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.797619 0.000000 0.000000 0.083333 0.000000 0.071429 0.000000 0.000000 0.000000 0.000000 0.000000 0.023810 0.000000 0.011905 0.000000 0.011905 0.178571 0.023810 0.000000 0.000000 0.023810 0.083333 0.059524 0.166667 0.000000 0.000000 0.035714 0.000000 0.047619 0.000000 0.000000 0.166667 0.083333 0.130952 0.000000 0.000000 0.035714 0.023810 0.059524 0.464286 0.000000 0.297619 0.000000 0.000000 0.011905 0.000000 0.011905 0.000000 0.000000 0.011905 0.023810 0.035714 0.011905 0.011905 0.000000 0.000000 0.035714 0.000000 0.678571 0.119048 0.000000 0.071429 0.000000 0.000000 0.000000 0.000000 0.000000 0.035714 0.000000 0.000000 0.000000 0.000000 0.000000 0.023810 0.000000 0.035714 0.130952 0.023810 0.000000 0.035714 0.023810 0.000000 0.000000 0.011905 0.011905 0.000000 0.011905 0.011905 0.023810 0.000000 0.000000 0.571429 0.023810 0.011905 0.000000 0.107143 0.023810 0.023810 0.750000 0.011905 0.000000 0.023810 0.011905 0.023810 0.000000 0.000000 0.000000 0.059524 0.011905 0.035714 0.000000 0.000000 0.000000 0.011905 0.000000 0.011905 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif PESAKDSNSFAEDSD MEME-4 regular expression -------------------------------------------------------------------------------- PESAKDSNSFX[EG]DSD -------------------------------------------------------------------------------- Time 178.56 secs. ******************************************************************************** ******************************************************************************** MOTIF DKELEDILYSNGVNP MEME-5 width = 15 sites = 82 llr = 1753 E-value = 7.8e-359 ******************************************************************************** -------------------------------------------------------------------------------- Motif DKELEDILYSNGVNP MEME-5 Description -------------------------------------------------------------------------------- Simplified A 1::::::::1::11: pos.-specific C ::::::::1:::::: probability D 6:1:36::::11:11 matrix E 117:73:::::1::: F :::1::111:::::: G :::::::::::7::: H ::::::::::::::: I ::11::21:::::1: K :6::::1::::::1: L :::4::28::::1:: M :::1::2:::::::: N :::::1::1:7::4: P :::::::::::::16 Q :1::::::::::::: R ::::::::::::::: S :::::::::81:::1 T ::::::::::::::: V :::1::::::::5:: W ::::::::::::::: Y ::::::::6:::::: bits 6.8 6.1 5.4 4.8 Relative 4.1 Entropy 3.4 (30.8 bits) 2.7 ** ** * 2.0 * ** ****** * 1.4 *************** 0.7 *************** 0.0 --------------- Multilevel DKELEDILYSNGVNP consensus DEL sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif DKELEDILYSNGVNP MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- --------------- XP_021622766.1 185 1.65e-18 DGIDSIEPYV DKELEDILYSNGVNP NRYVLSSGRW TKR66562.1 205 5.30e-18 VGTDSIETCT DKELDDILYSNGVNP NVHALSSGRW XP_021691173.1 175 5.30e-18 DGIDSIELCI DKELDDILYSNGVNP NMYVLSSGKW XP_027149457.1 180 1.40e-17 ECRAGFEEYT DKELEEMLYSNGVNP NNYVLSSGRW XP_009798034.1 207 2.40e-16 CRTEGIEMST EKELEDLLYSNGVNP NNYVLSSGRW XP_024028595.1 184 6.37e-16 YGADNLEQWT DKELEDILYANGLNP NEYVISSGRR TEY72131.1 192 7.40e-16 EGHAEIELYT DKELEDLLYSNGAAP GGTFILSSGR XP_004514391.1 186 7.40e-16 YDKDNIDQSV DKEFEDFLCSNGVNP DTYVLSSGRW XP_021650240.1 197 7.40e-16 DGIDSIEPCI DKELDDILNSNGVNP NVYVLSSGRW XP_019162543.1 192 1.19e-15 CGNENIETCT DKELEDMLYSNGIAP DNFVLSSGRW XP_013448883.1 159 1.37e-15 VKDSGDDQSI DKEFEDFLFSNGVNP DKYVLSSGRL XP_027176296.1 190 4.52e-15 ECRASFEGYT DKELEEMLYSNGATP NNYVLSSERW RAL39303.1 157 6.01e-15 CEKEKMGRPT EQELEDMLYSNGVIP NSFVLSSGRW XP_011077640.1 233 2.07e-14 YRNEGIEHCT EKELENLLYSNGVAP GNYVLSSGRW XP_019459351.1 186 4.56e-14 LAEDNSEHSI DKECEDFLYSNKVNP HAYVLSSGQW XP_027353450.1 183 4.56e-14 HAKDSNEHSV DTEFEDFLFSNGVNP NMYVLSSGRW XP_018806280.1 192 6.70e-14 HGNDSFEQLT DKDIEDVLYSNGINP NKYVLSSGRW XP_004137783.2 295 9.77e-14 YENDDTKQCT DQELEELFYSNGLNP NTYILSSGRW XP_015896979.1 194 9.77e-14 CEYEDIEQCT DKELEDLLYSNRLNP NTYVLSSGRW PIN03316.1 158 1.25e-13 YRNDGIEQLT DKELENLLYSNGVAS SQYVLSSGRW XP_022983598.1 201 1.81e-13 YGHDETEQCT DQELEDLFYSNGLDP NAYILSSGRW XP_021289458.1 201 2.60e-13 YGNYPIEAYQ DKEIEEILNTNGANP NVYVLSSGRW XP_028773013.1 229 2.60e-13 HAKDNCEESM DKGFEDLLYSSGVNP NVYVLSSGRW XP_022747248.1 197 2.93e-13 YGNYNIEQYQ DKEIEEILNSNGAKP NVYVLSSGRW TKY66008.1 174 4.18e-13 YAKDGNEDPV DKEFEDFLFSTGVNP NVYVLSSGRW XP_004302767.1 203 1.17e-12 YGEHFIEECT DKEVEDIIYSNSLNP HAYILSSGRW XP_024189435.1 205 1.17e-12 YGDHFIEECT DKEVEDIIYSNSLNP HTYVLSSGRW OAY41326.1 142 1.31e-12 DGIDSIEPNM DKDLDDILYSNGNNS NIRVFFHLVT XP_017416333.1 180 1.31e-12 YAKESNEYPV DKEFEDFLFSSGVDP NVYVLSSGRW XP_018841755.1 169 3.93e-12 YGNDCIEQPT DNELEDILDSHGVNP TNMYVLSSER XP_022145567.1 196 4.38e-12 YGNDDIEQCT DQELEELFYSNGLNQ NTYLLSSGRW PNX96427.1 162 4.87e-12 VKDSSDDQLI DKELEEFLISHGVIP DKYALSSGIL GAV76568.1 212 6.02e-12 KYANVSVELA EKELEDALYSSGLNP NSYVHSFGRW XP_022846646.1 191 6.02e-12 YRIDGFGHST DKELEDMLYLNDVAS SSYVLSSGRW OMO66336.1 197 1.01e-11 YGNYTIEQYQ EKEIEEILNSNGANQ NVYVLSSGRW XP_012442486.1 230 1.01e-11 YGNYTREQHQ DKEIEEILNCDGANP NVYILSSGRW XP_022742854.1 201 1.01e-11 YGNYAIEQYQ DKEIEEILNCDGANP NVYVLSSGRW XP_022948410.1 177 2.29e-11 HVNDDLEQCT EQELEDLFRSNGLNP NTYVLSSGRW TKS09656.1 209 2.80e-11 FGTDNIEPCT DKEVDDILYSNELNL NGHVLSSEGW PON90845.1 193 3.76e-11 YGDEELEQCT DKELEDILCASGLNR NVYVLSSGRW XP_015960799.1 137 6.73e-11 EDGKDGAELA IEEFEDFLLSNGVDP NMYVLSSGRR VAI07274.1 207 8.15e-11 LAGGGVDGSA DRIMDETLYSNGVDD FMILPAGEKK XP_021307618.1 247 1.08e-10 LMADDVFGSA AQIMDEKLYSNGVDD IQILPTGQTG XP_020553487.1 192 1.19e-10 YQNDGTEHHC NKDLGDLLYSSGVAP SNYVLSSGRW RLN19347.1 217 2.28e-10 LVNGNAYGSA AHIMEEKLYSNGVDD LQILPAGQTG XP_023734875.1 158 2.28e-10 EEELDCGENE TKQMEDFFCSNDVIP DNFVLSSGRW PKI43461.1 189 3.28e-10 NGIDLMEQSG DNRTEDVLYSSGMNP NSYVLSSGRW RXI02216.1 203 4.29e-10 HGDDCIEECM DTGCEDLIYPNGLKP NTYVLSSGRW XP_012074964.1 205 4.29e-10 HGTDSIEPFI RKELDDILYPKGVDS NVYVLSSGRW OEL29447.1 313 5.60e-10 LASGNVYGSG AYIMDEKLYSNGVDD FQILPTGQTG XP_010937591.1 228 6.12e-10 FGKSASEHLD ATTKDEMLYSNDVAP NAFVLPSGSW XP_024982170.1 187 6.12e-10 FDSSEYKNGG TKPLDDLFCSDGVIP DNFVLSSGRW PIN04755.1 175 6.68e-10 LEFDGIEHCT QEDLDNLLYANGVVP NNYILSSGRW RVW33794.1 208 6.68e-10 YRDGMVEHST DKELADMPYSSGMKP NNYVLSSGRW XP_023913884.1 193 8.68e-10 YDADYNFLEY GESIEDTLYSNGSNP NTYVLSSRRW XP_010047842.1 191 1.13e-09 EGKDFIDQCH DDETEDIIYSNGEPS NNFVLSSGRW XP_008803152.1 282 1.23e-09 FGKNATEHLD AATKDEMLYSNDVTP DAFVLSSGRW RWW70318.1 93 3.64e-09 LGKNSLEHLD AEIEDLMLYSNDVAP HALLVSPERW XP_008240727.1 175 4.65e-09 YGEDCIDQCK DKEIEDVIYPIGSNT NKYILSSGRW XP_028119329.1 189 5.05e-09 LGNENIEECT DKEVEDMLCSDEPSP NNYVLSSGRW XP_028783417.1 155 5.93e-09 YVRDGNMHSI EKEVEDVFSTHGAIP NMYILSSGKW PSS23773.1 155 8.83e-09 GNDDNMERLV NMELDDMLNANKAGP STTFVLSSNQ NP_001354359.1 220 9.56e-09 LMAGDVFGSA AQVMDEKLYSNSVDD FQILPTGQTG XP_002531564.2 209 1.12e-08 HGIESIEPCT DNVPDDMLSANEANP NMFILSSGRW XP_027336786.1 201 1.31e-08 HVCQEYAEDV DMEFEDFLFAQGGNR NMYVLSSGRW XP_014752653.1 199 1.65e-08 LASGGVDGFS DRITNERLYSNGVED FLILPAGKTG XP_010256878.1 209 2.61e-08 DEGIQQYLDE EEDDDMLLYSNGATS NLFVLSSGRW EEC74952.1 218 3.03e-08 LGSGDVDGSA AGVIDEKLYSNGIED LLILPRGQNS XP_006349495.1 209 3.52e-08 CRTEGVELTT EKELENLLNANVNPS NYVLSSGRWT PHT70537.1 221 3.79e-08 CRTEDIELAM EKELENLLNSNVNPN NYVLSSGRWT PSS34997.1 209 5.89e-08 HGNDSMELCK HKEPEDMLYSDETPQ NNYVLSSGRW TEY25303.1 191 6.33e-08 YHNEVIEGCV DEGVDNQLYSNEATD CNFVLSSGRW XP_010037822.1 205 6.81e-08 YANDCLDTCA TEEVEDSIYSNASKP DNLVLSSGRW XP_020268040.1 124 7.32e-08 QDKLCAENQF EDETIEEIYSNDVAP FLLASGKCSI PWA88889.1 85 7.87e-08 KNTSDYTTKQ LEELEDLFCPDGVII SNNYVLSSGR RWR86109.1 201 1.21e-07 KNDGKEHSTE IAAEEMMLYSNDVPS NLYVLSSGRW XP_010678090.1 176 1.39e-07 HYFKDNKQQT VAELEGFLSSSGVNT NLYVPSPDRW EPS60070.1 132 3.39e-07 VDPNVHLEQS GSRDDDDLYSSGVGP FTHLILSENR GAY47919.1 232 6.15e-07 LDHFAAEHFT EKEIGETLDSKEGNP NVYVLSSGRW XP_022039957.1 125 8.49e-07 EEEEEDNSEF SSSMEDLFCSNAVIS NNSVLSSGRW VDD15356.1 317 1.81e-06 YGTQNLEDFS DKDIENILYLDDEEE EDEANGCSNA PIA54706.1 64 2.95e-06 GSKHLSPLVE DLEVEDILQTLMVKV NSNTVHHESK -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif DKELEDILYSNGVNP MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- XP_021622766.1 1.7e-18 184_[5]_38 TKR66562.1 5.3e-18 204_[5]_38 XP_021691173.1 5.3e-18 174_[5]_63 XP_027149457.1 1.4e-17 179_[5]_38 XP_009798034.1 2.4e-16 206_[5]_38 XP_024028595.1 6.4e-16 183_[5]_38 TEY72131.1 7.4e-16 191_[5]_43 XP_004514391.1 7.4e-16 185_[5]_38 XP_021650240.1 7.4e-16 196_[5]_38 XP_019162543.1 1.2e-15 191_[5]_38 XP_013448883.1 1.4e-15 158_[5]_40 XP_027176296.1 4.5e-15 189_[5]_38 RAL39303.1 6e-15 156_[5]_40 XP_011077640.1 2.1e-14 232_[5]_38 XP_019459351.1 4.6e-14 185_[5]_38 XP_027353450.1 4.6e-14 182_[5]_38 XP_018806280.1 6.7e-14 191_[5]_39 XP_004137783.2 9.8e-14 294_[5]_38 XP_015896979.1 9.8e-14 193_[5]_38 PIN03316.1 1.3e-13 157_[5]_38 XP_022983598.1 1.8e-13 200_[5]_38 XP_021289458.1 2.6e-13 200_[5]_38 XP_028773013.1 2.6e-13 228_[5]_38 XP_022747248.1 2.9e-13 196_[5]_38 TKY66008.1 4.2e-13 173_[5]_38 XP_004302767.1 1.2e-12 202_[5]_39 XP_024189435.1 1.2e-12 204_[5]_39 OAY41326.1 1.3e-12 141_[5]_39 XP_017416333.1 1.3e-12 179_[5]_38 XP_018841755.1 3.9e-12 168_[5]_39 XP_022145567.1 4.4e-12 195_[5]_38 PNX96427.1 4.9e-12 161_[5]_39 GAV76568.1 6e-12 211_[5]_38 XP_022846646.1 6e-12 190_[5]_40 OMO66336.1 1e-11 196_[5]_38 XP_012442486.1 1e-11 229_[5]_38 XP_022742854.1 1e-11 200_[5]_38 XP_022948410.1 2.3e-11 176_[5]_38 TKS09656.1 2.8e-11 208_[5]_38 PON90845.1 3.8e-11 192_[5]_38 XP_015960799.1 6.7e-11 136_[5]_38 VAI07274.1 8.2e-11 206_[5]_28 XP_021307618.1 1.1e-10 246_[5]_32 XP_020553487.1 1.2e-10 191_[5]_38 RLN19347.1 2.3e-10 216_[5]_32 XP_023734875.1 2.3e-10 157_[5]_38 PKI43461.1 3.3e-10 188_[5]_38 RXI02216.1 4.3e-10 202_[5]_40 XP_012074964.1 4.3e-10 204_[5]_38 OEL29447.1 5.6e-10 312_[5]_32 XP_010937591.1 6.1e-10 227_[5]_38 XP_024982170.1 6.1e-10 186_[5]_38 PIN04755.1 6.7e-10 174_[5]_38 RVW33794.1 6.7e-10 207_[5]_38 XP_023913884.1 8.7e-10 192_[5]_38 XP_010047842.1 1.1e-09 190_[5]_38 XP_008803152.1 1.2e-09 281_[5]_43 RWW70318.1 3.6e-09 92_[5]_38 XP_008240727.1 4.7e-09 174_[5]_42 XP_028119329.1 5e-09 188_[5]_38 XP_028783417.1 5.9e-09 154_[5]_38 PSS23773.1 8.8e-09 154_[5]_34 NP_001354359.1 9.6e-09 219_[5]_32 XP_002531564.2 1.1e-08 208_[5]_38 XP_027336786.1 1.3e-08 200_[5]_38 XP_014752653.1 1.6e-08 198_[5]_33 XP_010256878.1 2.6e-08 208_[5]_38 EEC74952.1 3e-08 217_[5]_33 XP_006349495.1 3.5e-08 208_[5]_37 PHT70537.1 3.8e-08 220_[5]_37 PSS34997.1 5.9e-08 208_[5]_38 TEY25303.1 6.3e-08 190_[5]_38 XP_010037822.1 6.8e-08 204_[5]_38 XP_020268040.1 7.3e-08 123_[5]_36 PWA88889.1 7.9e-08 84_[5]_39 RWR86109.1 1.2e-07 200_[5]_38 XP_010678090.1 1.4e-07 175_[5]_38 EPS60070.1 3.4e-07 131_[5]_33 GAY47919.1 6.1e-07 231_[5]_38 XP_022039957.1 8.5e-07 124_[5]_43 VDD15356.1 1.8e-06 316_[5]_49 PIA54706.1 2.9e-06 63_[5]_185 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif DKELEDILYSNGVNP MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF DKELEDILYSNGVNP width=15 seqs=82 XP_021622766.1 ( 185) DKELEDILYSNGVNP 1 TKR66562.1 ( 205) DKELDDILYSNGVNP 1 XP_021691173.1 ( 175) DKELDDILYSNGVNP 1 XP_027149457.1 ( 180) DKELEEMLYSNGVNP 1 XP_009798034.1 ( 207) EKELEDLLYSNGVNP 1 XP_024028595.1 ( 184) DKELEDILYANGLNP 1 TEY72131.1 ( 192) DKELEDLLYSNGAAP 1 XP_004514391.1 ( 186) DKEFEDFLCSNGVNP 1 XP_021650240.1 ( 197) DKELDDILNSNGVNP 1 XP_019162543.1 ( 192) DKELEDMLYSNGIAP 1 XP_013448883.1 ( 159) DKEFEDFLFSNGVNP 1 XP_027176296.1 ( 190) DKELEEMLYSNGATP 1 RAL39303.1 ( 157) EQELEDMLYSNGVIP 1 XP_011077640.1 ( 233) EKELENLLYSNGVAP 1 XP_019459351.1 ( 186) DKECEDFLYSNKVNP 1 XP_027353450.1 ( 183) DTEFEDFLFSNGVNP 1 XP_018806280.1 ( 192) DKDIEDVLYSNGINP 1 XP_004137783.2 ( 295) DQELEELFYSNGLNP 1 XP_015896979.1 ( 194) DKELEDLLYSNRLNP 1 PIN03316.1 ( 158) DKELENLLYSNGVAS 1 XP_022983598.1 ( 201) DQELEDLFYSNGLDP 1 XP_021289458.1 ( 201) DKEIEEILNTNGANP 1 XP_028773013.1 ( 229) DKGFEDLLYSSGVNP 1 XP_022747248.1 ( 197) DKEIEEILNSNGAKP 1 TKY66008.1 ( 174) DKEFEDFLFSTGVNP 1 XP_004302767.1 ( 203) DKEVEDIIYSNSLNP 1 XP_024189435.1 ( 205) DKEVEDIIYSNSLNP 1 OAY41326.1 ( 142) DKDLDDILYSNGNNS 1 XP_017416333.1 ( 180) DKEFEDFLFSSGVDP 1 XP_018841755.1 ( 169) DNELEDILDSHGVNP 1 XP_022145567.1 ( 196) DQELEELFYSNGLNQ 1 PNX96427.1 ( 162) DKELEEFLISHGVIP 1 GAV76568.1 ( 212) EKELEDALYSSGLNP 1 XP_022846646.1 ( 191) DKELEDMLYLNDVAS 1 OMO66336.1 ( 197) EKEIEEILNSNGANQ 1 XP_012442486.1 ( 230) DKEIEEILNCDGANP 1 XP_022742854.1 ( 201) DKEIEEILNCDGANP 1 XP_022948410.1 ( 177) EQELEDLFRSNGLNP 1 TKS09656.1 ( 209) DKEVDDILYSNELNL 1 PON90845.1 ( 193) DKELEDILCASGLNR 1 XP_015960799.1 ( 137) IEEFEDFLLSNGVDP 1 VAI07274.1 ( 207) DRIMDETLYSNGVDD 1 XP_021307618.1 ( 247) AQIMDEKLYSNGVDD 1 XP_020553487.1 ( 192) NKDLGDLLYSSGVAP 1 RLN19347.1 ( 217) AHIMEEKLYSNGVDD 1 XP_023734875.1 ( 158) TKQMEDFFCSNDVIP 1 PKI43461.1 ( 189) DNRTEDVLYSSGMNP 1 RXI02216.1 ( 203) DTGCEDLIYPNGLKP 1 XP_012074964.1 ( 205) RKELDDILYPKGVDS 1 OEL29447.1 ( 313) AYIMDEKLYSNGVDD 1 XP_010937591.1 ( 228) ATTKDEMLYSNDVAP 1 XP_024982170.1 ( 187) TKPLDDLFCSDGVIP 1 PIN04755.1 ( 175) QEDLDNLLYANGVVP 1 RVW33794.1 ( 208) DKELADMPYSSGMKP 1 XP_023913884.1 ( 193) GESIEDTLYSNGSNP 1 XP_010047842.1 ( 191) DDETEDIIYSNGEPS 1 XP_008803152.1 ( 282) AATKDEMLYSNDVTP 1 RWW70318.1 ( 93) AEIEDLMLYSNDVAP 1 XP_008240727.1 ( 175) DKEIEDVIYPIGSNT 1 XP_028119329.1 ( 189) DKEVEDMLCSDEPSP 1 XP_028783417.1 ( 155) EKEVEDVFSTHGAIP 1 PSS23773.1 ( 155) NMELDDMLNANKAGP 1 NP_001354359.1 ( 220) AQVMDEKLYSNSVDD 1 XP_002531564.2 ( 209) DNVPDDMLSANEANP 1 XP_027336786.1 ( 201) DMEFEDFLFAQGGNR 1 XP_014752653.1 ( 199) DRITNERLYSNGVED 1 XP_010256878.1 ( 209) EEDDDMLLYSNGATS 1 EEC74952.1 ( 218) AGVIDEKLYSNGIED 1 XP_006349495.1 ( 209) EKELENLLNANVNPS 1 PHT70537.1 ( 221) EKELENLLNSNVNPN 1 PSS34997.1 ( 209) HKEPEDMLYSDETPQ 1 TEY25303.1 ( 191) DEGVDNQLYSNEATD 1 XP_010037822.1 ( 205) TEEVEDSIYSNASKP 1 XP_020268040.1 ( 124) EDETIEEIYSNDVAP 1 PWA88889.1 ( 85) LEELEDLFCPDGVII 1 RWR86109.1 ( 201) IAAEEMMLYSNDVPS 1 XP_010678090.1 ( 176) VAELEGFLSSSGVNT 1 EPS60070.1 ( 132) GSRDDDDLYSSGVGP 1 GAY47919.1 ( 232) EKEIGETLDSKEGNP 1 XP_022039957.1 ( 125) SSSMEDLFCSNAVIS 1 VDD15356.1 ( 317) DKDIENILYLDDEEE 1 PIA54706.1 ( 64) DLEVEDILQTLMVKV 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif DKELEDILYSNGVNP MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 20 w= 15 n= 26933 bayes= 9.32252 E= 7.8e-359 92 -500 290 43 -483 -119 -99 -84 -271 -250 -405 -100 -420 -133 -114 -290 -36 -169 -430 -425 -19 -509 -144 -1 -483 -190 -88 -423 315 -239 -20 -51 -406 103 -29 -212 -23 -371 -434 -136 -157 -643 0 270 -611 -58 -425 80 -347 -540 -502 -434 -164 -136 -44 -230 -84 -26 -562 -544 -312 20 -169 -205 124 -507 -470 173 -127 237 159 -538 -76 -483 -445 -538 10 122 -377 -407 -174 -884 174 276 -835 -115 -561 -173 -456 -678 -648 -208 -566 -369 -528 -634 -527 -575 -776 -729 -445 -780 298 138 -788 -205 -516 -676 -469 -267 -23 60 -573 -396 -526 -589 -511 -597 -735 -684 -147 -389 -262 -295 170 -502 -465 256 1 154 257 -530 -520 -168 -142 -316 -25 37 -378 -406 -596 -626 -922 -863 143 -807 -712 109 -774 333 -311 -828 -176 -666 -664 -865 -616 -393 -521 -598 -235 162 -182 -440 112 -408 -115 -147 -372 -205 -298 59 -385 -178 -140 -193 -328 -267 -134 417 80 11 -627 -690 -581 -449 -565 -548 -550 -178 -537 -451 14 -555 -477 254 8 -493 -539 -578 -363 -397 -72 -533 -428 -379 -8 -210 -194 -314 -409 382 -416 -209 -344 -108 -196 -370 -326 -406 -96 -497 -4 -86 -581 378 -471 -536 -155 -605 -155 -398 -505 -501 -166 -208 -463 -118 -449 -539 157 -374 -643 -207 -361 -118 -459 11 -506 87 -10 -68 -171 -479 -432 -185 -152 350 -378 -409 120 -517 49 -122 -492 -108 -320 100 16 -446 -405 287 54 -262 -254 -280 12 -160 -444 -429 -285 -522 17 -296 -549 -480 -474 -177 -447 -259 -516 -224 405 -33 -63 -43 -97 -179 -547 -588 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif DKELEDILYSNGVNP MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 20 w= 15 nsites= 82 E= 7.8e-359 0.097561 0.000000 0.573171 0.146341 0.000000 0.024390 0.012195 0.024390 0.000000 0.012195 0.000000 0.024390 0.000000 0.012195 0.012195 0.012195 0.036585 0.012195 0.000000 0.000000 0.036585 0.000000 0.024390 0.097561 0.000000 0.012195 0.012195 0.000000 0.560976 0.012195 0.024390 0.036585 0.000000 0.085366 0.024390 0.024390 0.036585 0.000000 0.000000 0.012195 0.012195 0.000000 0.073171 0.670732 0.000000 0.036585 0.000000 0.073171 0.000000 0.000000 0.000000 0.000000 0.012195 0.012195 0.024390 0.024390 0.024390 0.036585 0.000000 0.000000 0.000000 0.024390 0.024390 0.024390 0.097561 0.000000 0.000000 0.134146 0.024390 0.414634 0.085366 0.000000 0.024390 0.000000 0.000000 0.000000 0.048780 0.097561 0.000000 0.000000 0.012195 0.000000 0.256098 0.682927 0.000000 0.024390 0.000000 0.012195 0.000000 0.000000 0.000000 0.012195 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.609756 0.256098 0.000000 0.012195 0.000000 0.000000 0.000000 0.012195 0.024390 0.085366 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.012195 0.000000 0.012195 0.012195 0.134146 0.000000 0.000000 0.243902 0.060976 0.231707 0.170732 0.000000 0.000000 0.012195 0.012195 0.012195 0.036585 0.048780 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.109756 0.000000 0.000000 0.085366 0.000000 0.792683 0.000000 0.000000 0.012195 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.085366 0.024390 0.000000 0.060976 0.000000 0.000000 0.012195 0.000000 0.012195 0.000000 0.109756 0.000000 0.012195 0.012195 0.036585 0.000000 0.000000 0.000000 0.634146 0.085366 0.024390 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.024390 0.000000 0.000000 0.048780 0.000000 0.000000 0.780488 0.036585 0.000000 0.000000 0.000000 0.000000 0.000000 0.085366 0.000000 0.000000 0.000000 0.036585 0.012195 0.024390 0.012195 0.000000 0.695122 0.000000 0.012195 0.000000 0.109756 0.012195 0.000000 0.000000 0.000000 0.024390 0.000000 0.097561 0.073171 0.000000 0.695122 0.000000 0.000000 0.024390 0.000000 0.012195 0.000000 0.000000 0.000000 0.012195 0.036585 0.000000 0.024390 0.000000 0.000000 0.146341 0.000000 0.000000 0.024390 0.000000 0.024390 0.000000 0.036585 0.000000 0.146341 0.024390 0.036585 0.012195 0.000000 0.000000 0.036585 0.012195 0.500000 0.000000 0.000000 0.109756 0.000000 0.109756 0.036585 0.000000 0.024390 0.000000 0.085366 0.060976 0.000000 0.000000 0.439024 0.060976 0.000000 0.000000 0.012195 0.048780 0.012195 0.000000 0.000000 0.000000 0.000000 0.097561 0.012195 0.000000 0.000000 0.000000 0.012195 0.000000 0.012195 0.000000 0.012195 0.646341 0.036585 0.024390 0.109756 0.024390 0.012195 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif DKELEDILYSNGVNP MEME-5 regular expression -------------------------------------------------------------------------------- DKEL[ED][DE][IL]LYSNGVNP -------------------------------------------------------------------------------- Time 212.07 secs. ******************************************************************************** ******************************************************************************** MOTIF NLEEHLLEFGSHVDYICSEYG MEME-6 width = 21 sites = 62 llr = 1770 E-value = 1.7e-359 ******************************************************************************** -------------------------------------------------------------------------------- Motif NLEEHLLEFGSHVDYICSEYG MEME-6 Description -------------------------------------------------------------------------------- Simplified A ::::::::::::1::::1::1 pos.-specific C ::::::::::::::1:5::1: probability D 1:21:::::1:::6::::11: matrix E ::78:::8:2::11::::6:1 F :1::::::5:::1:::1:::: G :::::::1:61:11::::1:5 H :1::4::::::5::1::::1: I :::::2::1:::1::3::::: K 1:::::::::::::::::::: L :5:::65:2:::1::::1:1: M ::::::::::::::::::::: N 6:::::::::3::1:11:::: P ::::1:::::::::::::::: Q ::1:2:1:::::::::::1:: R :::::::::::1::::::::1 S ::::1:::::4:2::216::: T ::::::::::1::::1::::: V ::::::2:::::2::1::::: W ::::::::::::::::::::: Y :2::::::1::1::5:2::4: bits 6.8 6.1 5.4 4.8 Relative 4.1 Entropy 3.4 (41.2 bits) 2.7 * * * * 2.0 ********** * ** * ** 1.4 ************ ** ***** 0.7 ********************* 0.0 --------------------- Multilevel NLEEHLLEFGSHXDYICSEYG consensus D Q LEN sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif NLEEHLLEFGSHVDYICSEYG MEME-6 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- --------------------- PON90845.1 164 3.97e-22 QHEERMQAYL NLEEQLLEFGNHGDYINSEYG DEELEQCTDK PKI39361.1 185 4.66e-20 YIDEEPQFSE TLEEHLLEFGCHLGYTCSEYG NDCSQQCAAK XP_024028595.1 155 8.47e-20 SEEVESQAFL NLEEQLLEFGNHENYIASEYG ADNLEQWTDK XP_022846646.1 162 2.03e-19 HHNFGLYPSV NYEEHLLELTNHVDCSCSEYR IDGFGHSTDK XP_027149457.1 152 2.70e-19 HHDIGLKSSL NYEEHLLEFGSHGDCSCPECR AGFEEYTDKE XP_008240727.1 146 2.70e-19 YPDGEIQAFE NYDEHLQEFGNQVDYIFSEYG EDCIDQCKDK XP_022742854.1 172 3.12e-19 PELADVELAE NLDESLVEFGSHIDYIYSGYG NYAIEQYQDK XP_009798034.1 178 7.21e-19 HRGSGCHPSL DYEEHLLEFGNHGDCTCAECR TEGIEMSTEK XP_021289458.1 172 1.09e-18 PEPANVELAE NLEESIVEYGSHVDYIYSGYG NYPIEAYQDK XP_022747248.1 168 1.87e-18 PEPADVELAE NLEESLVEYGSHIDYIYSRYG NYNIEQYQDK RVW33794.1 179 2.79e-18 SGEHNPLVSQ NLEEQLLEFGNDIDFMCSEYR DGMVEHSTDK XP_027176296.1 162 3.63e-18 YHDIGLKSSL NYEEHLLEFGSHSNCSCLECR ASFEGYTDKE PHT70537.1 192 4.71e-18 HHGSGCNPSM DYEEHLLGFGNHGDCTCAECR TEDIELAMEK XP_010047842.1 162 1.02e-17 SHNSQLRVKQ ILEEHLLEFGNHADHICLEEG KDFIDQCHDD XP_024189435.1 176 1.16e-17 MNVEVHQPIQ NHEEQLQEFGGEANYICSEYG DHFIEECTDK XP_004302767.1 174 1.69e-17 VNMEVHQPIQ NLEEQLQEYGGEANYICSEYG EHFIEECTDK RXI02216.1 174 2.17e-17 HPHDKIQEFQ NLEEHIQEFGNRMDYIFAEHG DDCIEECMDT XP_021622766.1 156 2.17e-17 HGLDHHELHQ NLDEPIVEFGSHFDYTCTQDG IDSIEPYVDK XP_019162543.1 163 7.38e-17 DQNFGWHRSL NYEDHLLDFESHVECSCSECG NENIETCTDK PSS34997.1 180 1.06e-16 HNNFGLHTCL NFDEHLLELRTHIDYNCLEHG NDSMELCKHK XP_028119329.1 160 1.91e-16 HNDFGPHACL NFDEHLLEYGTHIDFNCLELG NENIEECTDK XP_012442486.1 201 2.14e-16 PEPADAKLAE NLDESLVEYGSDIDYIYSQYG NYTREQHQDK XP_015896979.1 167 2.14e-16 QHDDGIHLFQ NHEEHLIEFSNHVDYINCEYE DIEQCTDKEL XP_020553487.1 163 3.82e-16 HNDYATLPSD YYEDHLIEFGSHADCSCSEYQ NDGTEHHCNK XP_021650240.1 168 1.32e-15 HDLYHYELRQ DLDEPIVEFGSHFDYACSQDG IDSIEPCIDK TKR66562.1 176 1.65e-15 GHDDGLQASQ NLEEPILEFESPLDYSCSEVG TDSIETCTDK TKY66008.1 145 1.65e-15 YDDADIQALE NHEEHLLGLGSFSGHECSEYA KDGNEDPVDK OAY41326.1 113 2.29e-15 HGLHHHELHQ NLDEPIVELGSHFAYSCSQDG IDSIEPNMDK XP_018806280.1 163 2.55e-15 TLHDGSRAFQ NLDENLLEFSNEVDYSCSEHG NDSFEQLTDK XP_002531564.2 180 6.02e-15 LYHHYNELHQ NLEEATEEFRNHSDYMCSEHG IESIEPCTDN XP_004137783.2 266 6.69e-15 SGENRMETIQ KLQEQLLELDSHEDYNCAEYE NDDTKQCTDQ XP_006349495.1 180 6.69e-15 HHGSGCHPSM DYEEHFLGLGNHEGCTCAECR TEGVELTTEK XP_012074964.1 176 6.69e-15 PLHKCNGLHQ NFDDAIGEFESHSDYTCSEHG TDSIEPFIRK TKS09656.1 180 1.02e-14 CHYDGLQGYQ NLEEPILEIESPLNYSCSEFG TDNIEPCTDK XP_027336786.1 177 1.13e-14 YHYADIQALK NLEEQILELENRSNHVCQEYA EDVDMEFEDF OMO66336.1 168 2.10e-14 PEIADVDLTQ IPEDSHVEYGSHVDYIYSGYG NYTIEQYQEK GAV76568.1 184 7.04e-14 NDCKGCQVSW NLEDSPPGFECHVDCICSKYA NVSVELAEKE XP_022145567.1 167 2.49e-13 FVENRIETIH KLQEHMLELDNQEEYNCAEYG NDDIEQCTDQ XP_019459351.1 157 2.74e-13 YHEADTLTLE NYEEHLLGLESFSGHGYSELA EDNSEHSIDK XP_021691173.1 146 3.02e-13 HDLYHNVLHQ DLDEPNVKFGSHFNYICSQDG IDSIELCIDK TKY63306.1 182 7.02e-13 YHYADLQALK NLEQQILEIESRSDHVYREYA KDSTEESIDM XP_004514391.1 157 3.00e-12 YDDLDTQALE NPEERLLRLGTLSDHVYSEYD KDNIDQSVDK GAY47919.1 203 3.91e-12 DEHQTSHQFD DLNEHLTEFGSHAEYLYSGLD HFAAEHFTEK XP_022983598.1 172 1.11e-11 SGENRIETVH KVQEHLLELDSREGYDFAEYG HDETEQCTDQ XP_018841755.1 140 1.21e-11 SHHDELQAFQ TLEEHLVDLCDQVDYTSSVYG NDCIEQPTDN XP_028783417.1 126 1.31e-11 EREPFCDALM NLEEQSLALGICSDHVYSEYV RDGNMHSIEK PKI43461.1 164 1.43e-11 SRGGPINLRQ MLEEQLLEFTTHADYNGIDLM EQSGDNRTED XP_008803152.1 253 2.37e-11 DVQQSDSGYE TMEEHRPECETYGDYLFSEFG KNATEHLDAA XP_017416333.1 151 3.30e-11 YDDTDAQDLN NDEEHLMGIEGFSGRECSEYA KESNEYPVDK XP_028773013.1 200 5.40e-11 YHEADIQALQ NLEEQIVGCEKLKDDLYSEHA KDNCEESMDK XP_010037822.1 177 6.35e-11 PPDQDNELQM LLEEQLLEFGCHMGYTSEYAN DCLDTCATEE PIA54706.1 182 1.65e-10 KLCVGKDEAP FPDDQHLEYEYHADYACTDNE PEEIKECMDT OUZ99277.1 147 3.08e-10 GALQFDSGPQ NTELQLCEFEKYDDSICSGCT NDEIKECQDV XP_023544624.1 117 3.32e-10 GIKDNLDLNY GHEEDLLEFGNHGNSSIYEQC CSDSTQNLLL XP_018681881.1 64 7.05e-09 EVQQRDSRYK VAEEVAHEFEGYGDYTISSLG KNSLEQLETE TEY25303.1 164 7.05e-09 YHEYGLDLSE NYRVHLLECGSDCGFSEYHNE VIEGCVDEGV XP_010256878.1 178 1.59e-08 NGQQSESVSQ SIDTEFPEFGKYVDYISPAFG DEGIQQYLDE XP_022948410.1 153 2.89e-08 RGENQMEAIH KIQEHMLVLDSHEEHVNDDLE QCTEQELEDL XP_012850185.1 144 6.24e-08 NYQYGIDPSL PYEEHLEEFGNLCVEESTDKE LENYVLSSGR XP_023913884.1 172 7.54e-08 SHCDGLQAFQ NAEDDLLEFGNYDADYNFLEY GESIEDTLYS PSS23773.1 130 1.40e-07 LDDFGVHPCA SFDDHLLEFYSCLEDGNDDNM ERLVNMELDD XP_007134047.1 177 5.83e-07 YHYADLLALK NLEEKIIEIESSREAKDSTEE STDMEFEDLF -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif NLEEHLLEFGSHVDYICSEYG MEME-6 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- PON90845.1 4e-22 163_[6]_61 PKI39361.1 4.7e-20 184_[6]_58 XP_024028595.1 8.5e-20 154_[6]_61 XP_022846646.1 2e-19 161_[6]_63 XP_027149457.1 2.7e-19 151_[6]_60 XP_008240727.1 2.7e-19 145_[6]_65 XP_022742854.1 3.1e-19 171_[6]_61 XP_009798034.1 7.2e-19 177_[6]_61 XP_021289458.1 1.1e-18 171_[6]_61 XP_022747248.1 1.9e-18 167_[6]_61 RVW33794.1 2.8e-18 178_[6]_61 XP_027176296.1 3.6e-18 161_[6]_60 PHT70537.1 4.7e-18 191_[6]_60 XP_010047842.1 1e-17 161_[6]_61 XP_024189435.1 1.2e-17 175_[6]_62 XP_004302767.1 1.7e-17 173_[6]_62 RXI02216.1 2.2e-17 173_[6]_63 XP_021622766.1 2.2e-17 155_[6]_61 XP_019162543.1 7.4e-17 162_[6]_61 PSS34997.1 1.1e-16 179_[6]_61 XP_028119329.1 1.9e-16 159_[6]_61 XP_012442486.1 2.1e-16 200_[6]_61 XP_015896979.1 2.1e-16 166_[6]_59 XP_020553487.1 3.8e-16 162_[6]_61 XP_021650240.1 1.3e-15 167_[6]_61 TKR66562.1 1.6e-15 175_[6]_61 TKY66008.1 1.6e-15 144_[6]_61 OAY41326.1 2.3e-15 112_[6]_62 XP_018806280.1 2.5e-15 162_[6]_62 XP_002531564.2 6e-15 179_[6]_61 XP_004137783.2 6.7e-15 265_[6]_61 XP_006349495.1 6.7e-15 179_[6]_60 XP_012074964.1 6.7e-15 175_[6]_61 TKS09656.1 1e-14 179_[6]_61 XP_027336786.1 1.1e-14 176_[6]_56 OMO66336.1 2.1e-14 167_[6]_61 GAV76568.1 7e-14 183_[6]_60 XP_022145567.1 2.5e-13 166_[6]_61 XP_019459351.1 2.7e-13 156_[6]_61 XP_021691173.1 3e-13 145_[6]_86 TKY63306.1 7e-13 181_[6]_60 XP_004514391.1 3e-12 156_[6]_61 GAY47919.1 3.9e-12 202_[6]_61 XP_022983598.1 1.1e-11 171_[6]_61 XP_018841755.1 1.2e-11 139_[6]_62 XP_028783417.1 1.3e-11 125_[6]_61 PKI43461.1 1.4e-11 163_[6]_57 XP_008803152.1 2.4e-11 252_[6]_66 XP_017416333.1 3.3e-11 150_[6]_61 XP_028773013.1 5.4e-11 199_[6]_61 XP_010037822.1 6.4e-11 176_[6]_60 PIA54706.1 1.7e-10 181_[6]_61 OUZ99277.1 3.1e-10 146_[6]_62 XP_023544624.1 3.3e-10 116_[6]_56 XP_018681881.1 7.1e-09 63_[6]_68 TEY25303.1 7.1e-09 163_[6]_59 XP_010256878.1 1.6e-08 177_[6]_63 XP_022948410.1 2.9e-08 152_[6]_56 XP_012850185.1 6.2e-08 143_[6]_40 XP_023913884.1 7.5e-08 171_[6]_53 PSS23773.1 1.4e-07 129_[6]_53 XP_007134047.1 5.8e-07 176_[6]_54 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif NLEEHLLEFGSHVDYICSEYG MEME-6 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF NLEEHLLEFGSHVDYICSEYG width=21 seqs=62 PON90845.1 ( 164) NLEEQLLEFGNHGDYINSEYG 1 PKI39361.1 ( 185) TLEEHLLEFGCHLGYTCSEYG 1 XP_024028595.1 ( 155) NLEEQLLEFGNHENYIASEYG 1 XP_022846646.1 ( 162) NYEEHLLELTNHVDCSCSEYR 1 XP_027149457.1 ( 152) NYEEHLLEFGSHGDCSCPECR 1 XP_008240727.1 ( 146) NYDEHLQEFGNQVDYIFSEYG 1 XP_022742854.1 ( 172) NLDESLVEFGSHIDYIYSGYG 1 XP_009798034.1 ( 178) DYEEHLLEFGNHGDCTCAECR 1 XP_021289458.1 ( 172) NLEESIVEYGSHVDYIYSGYG 1 XP_022747248.1 ( 168) NLEESLVEYGSHIDYIYSRYG 1 RVW33794.1 ( 179) NLEEQLLEFGNDIDFMCSEYR 1 XP_027176296.1 ( 162) NYEEHLLEFGSHSNCSCLECR 1 PHT70537.1 ( 192) DYEEHLLGFGNHGDCTCAECR 1 XP_010047842.1 ( 162) ILEEHLLEFGNHADHICLEEG 1 XP_024189435.1 ( 176) NHEEQLQEFGGEANYICSEYG 1 XP_004302767.1 ( 174) NLEEQLQEYGGEANYICSEYG 1 RXI02216.1 ( 174) NLEEHIQEFGNRMDYIFAEHG 1 XP_021622766.1 ( 156) NLDEPIVEFGSHFDYTCTQDG 1 XP_019162543.1 ( 163) NYEDHLLDFESHVECSCSECG 1 PSS34997.1 ( 180) NFDEHLLELRTHIDYNCLEHG 1 XP_028119329.1 ( 160) NFDEHLLEYGTHIDFNCLELG 1 XP_012442486.1 ( 201) NLDESLVEYGSDIDYIYSQYG 1 XP_015896979.1 ( 167) NHEEHLIEFSNHVDYINCEYE 1 XP_020553487.1 ( 163) YYEDHLIEFGSHADCSCSEYQ 1 XP_021650240.1 ( 168) DLDEPIVEFGSHFDYACSQDG 1 TKR66562.1 ( 176) NLEEPILEFESPLDYSCSEVG 1 TKY66008.1 ( 145) NHEEHLLGLGSFSGHECSEYA 1 OAY41326.1 ( 113) NLDEPIVELGSHFAYSCSQDG 1 XP_018806280.1 ( 163) NLDENLLEFSNEVDYSCSEHG 1 XP_002531564.2 ( 180) NLEEATEEFRNHSDYMCSEHG 1 XP_004137783.2 ( 266) KLQEQLLELDSHEDYNCAEYE 1 XP_006349495.1 ( 180) DYEEHFLGLGNHEGCTCAECR 1 XP_012074964.1 ( 176) NFDDAIGEFESHSDYTCSEHG 1 TKS09656.1 ( 180) NLEEPILEIESPLNYSCSEFG 1 XP_027336786.1 ( 177) NLEEQILELENRSNHVCQEYA 1 OMO66336.1 ( 168) IPEDSHVEYGSHVDYIYSGYG 1 GAV76568.1 ( 184) NLEDSPPGFECHVDCICSKYA 1 XP_022145567.1 ( 167) KLQEHMLELDNQEEYNCAEYG 1 XP_019459351.1 ( 157) NYEEHLLGLESFSGHGYSELA 1 XP_021691173.1 ( 146) DLDEPNVKFGSHFNYICSQDG 1 TKY63306.1 ( 182) NLEQQILEIESRSDHVYREYA 1 XP_004514391.1 ( 157) NPEERLLRLGTLSDHVYSEYD 1 GAY47919.1 ( 203) DLNEHLTEFGSHAEYLYSGLD 1 XP_022983598.1 ( 172) KVQEHLLELDSREGYDFAEYG 1 XP_018841755.1 ( 140) TLEEHLVDLCDQVDYTSSVYG 1 XP_028783417.1 ( 126) NLEEQSLALGICSDHVYSEYV 1 PKI43461.1 ( 164) MLEEQLLEFTTHADYNGIDLM 1 XP_008803152.1 ( 253) TMEEHRPECETYGDYLFSEFG 1 XP_017416333.1 ( 151) NDEEHLMGIEGFSGRECSEYA 1 XP_028773013.1 ( 200) NLEEQIVGCEKLKDDLYSEHA 1 XP_010037822.1 ( 177) LLEEQLLEFGCHMGYTSEYAN 1 PIA54706.1 ( 182) FPDDQHLEYEYHADYACTDNE 1 OUZ99277.1 ( 147) NTELQLCEFEKYDDSICSGCT 1 XP_023544624.1 ( 117) GHEEDLLEFGNHGNSSIYEQC 1 XP_018681881.1 ( 64) VAEEVAHEFEGYGDYTISSLG 1 TEY25303.1 ( 164) NYRVHLLECGSDCGFSEYHNE 1 XP_010256878.1 ( 178) SIDTEFPEFGKYVDYISPAFG 1 XP_022948410.1 ( 153) KIQEHMLVLDSHEEHVNDDLE 1 XP_012850185.1 ( 144) PYEEHLEEFGNLCVEESTDKE 1 XP_023913884.1 ( 172) NAEDDLLEFGNYDADYNFLEY 1 PSS23773.1 ( 130) SFDDHLLEFYSCLEDGNDDNM 1 XP_007134047.1 ( 177) NLEEKIIEIESSREAKDSTEE 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif NLEEHLLEFGSHVDYICSEYG MEME-6 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 20 w= 21 n= 26237 bayes= 7.95653 E= 1.7e-359 -334 -381 -67 -495 -218 -233 -151 -120 -91 -288 -172 376 -215 -303 -319 -225 -79 -205 -311 -192 -41 -356 -230 -580 64 -474 118 -1 -481 264 -48 -503 15 -443 -405 -505 -122 -67 -339 240 -388 -869 156 274 -803 -549 -530 -620 -415 -636 -606 -172 -527 65 -109 -604 -491 -533 -742 -698 -387 -875 78 299 -803 -556 -535 -616 -415 -228 -603 -525 -527 -109 -490 -610 -148 -142 -739 -701 -30 -474 -109 -192 -444 -365 393 -393 -112 -404 -362 -136 114 233 -65 -46 -262 -124 -396 -370 -164 -402 -623 -563 -49 -532 -16 185 -473 310 22 -217 -166 -404 -137 -327 -166 -200 -344 -403 -305 -53 -628 -184 -293 -188 -87 35 -477 287 -43 -515 1 38 -392 -526 -139 184 -342 -384 -135 -875 -95 295 -803 99 -533 -618 -166 -634 -603 -519 -526 -324 -109 -608 -491 -140 -741 -699 -641 117 -916 -913 376 -797 -526 71 -802 155 -377 -759 -762 -684 -682 -856 -654 -447 -362 179 -371 -49 -23 116 -636 339 -409 -613 -429 -645 -608 -292 -522 -429 -18 -194 -56 -556 -558 -112 -399 114 -177 -463 -627 25 -390 -134 -25 -623 -597 235 -517 -405 -415 163 79 -558 -588 -104 -368 7 -108 -152 -17 -433 454 -440 -454 -110 -349 -206 -81 17 51 -294 -330 -382 -266 94 124 57 -127 -12 66 96 -402 130 -169 -14 30 -453 -465 -393 -100 21 -293 189 -346 -370 -52 -657 295 0 -707 121 -428 -685 -459 -703 -691 122 -550 -422 -491 -497 -450 -144 -664 -600 -109 226 -103 -258 108 -379 196 -257 -343 -270 -269 -367 -356 -343 -112 -207 -299 -239 -105 401 -32 -396 -203 -98 -369 -75 -338 266 -142 -57 24 47 -420 -296 -282 35 157 92 -364 -96 -127 454 -189 -241 65 -156 -398 -25 -418 -420 -406 57 -506 -408 -407 -99 -363 -332 -467 235 74 -76 -175 -299 -177 -371 -388 -171 -357 -90 -373 -274 -87 -174 -134 226 89 -385 -375 -66 -95 -475 6 248 -448 48 -52 -389 -109 -203 -360 -294 -372 96 -64 -242 -107 -122 -400 -100 -108 191 -66 -138 108 -379 162 -257 -184 -2 -269 -59 -355 -149 -272 -378 -298 -118 -105 375 121 -49 -109 16 -448 306 -280 -388 -218 -402 14 -138 -374 -85 161 -369 -109 -123 -399 -101 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif NLEEHLLEFGSHVDYICSEYG MEME-6 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 20 w= 21 nsites= 62 E= 1.7e-359 0.000000 0.000000 0.096774 0.000000 0.016129 0.016129 0.000000 0.032258 0.064516 0.016129 0.016129 0.612903 0.016129 0.000000 0.000000 0.032258 0.048387 0.016129 0.000000 0.016129 0.032258 0.000000 0.016129 0.000000 0.064516 0.000000 0.064516 0.032258 0.000000 0.500000 0.016129 0.000000 0.048387 0.000000 0.000000 0.000000 0.016129 0.016129 0.000000 0.193548 0.000000 0.000000 0.225806 0.677419 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.016129 0.000000 0.064516 0.016129 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.129032 0.806452 0.000000 0.000000 0.000000 0.000000 0.000000 0.016129 0.000000 0.000000 0.000000 0.016129 0.000000 0.000000 0.016129 0.016129 0.000000 0.000000 0.032258 0.000000 0.032258 0.016129 0.000000 0.000000 0.435484 0.000000 0.016129 0.000000 0.000000 0.016129 0.096774 0.225806 0.016129 0.096774 0.000000 0.016129 0.000000 0.000000 0.016129 0.000000 0.000000 0.000000 0.032258 0.000000 0.032258 0.193548 0.000000 0.612903 0.032258 0.016129 0.016129 0.000000 0.016129 0.016129 0.016129 0.000000 0.000000 0.000000 0.000000 0.016129 0.000000 0.032258 0.000000 0.016129 0.016129 0.048387 0.000000 0.548387 0.016129 0.000000 0.048387 0.064516 0.000000 0.000000 0.016129 0.177419 0.000000 0.000000 0.016129 0.000000 0.032258 0.790323 0.000000 0.112903 0.000000 0.000000 0.016129 0.000000 0.000000 0.000000 0.000000 0.000000 0.016129 0.000000 0.000000 0.016129 0.000000 0.000000 0.000000 0.048387 0.000000 0.000000 0.548387 0.000000 0.000000 0.064516 0.000000 0.225806 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.112903 0.000000 0.016129 0.064516 0.241935 0.000000 0.564516 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.032258 0.032258 0.032258 0.000000 0.000000 0.016129 0.000000 0.048387 0.016129 0.000000 0.000000 0.064516 0.000000 0.016129 0.048387 0.000000 0.000000 0.290323 0.000000 0.000000 0.000000 0.419355 0.080645 0.000000 0.000000 0.016129 0.000000 0.032258 0.048387 0.048387 0.048387 0.000000 0.532258 0.000000 0.000000 0.048387 0.000000 0.000000 0.032258 0.048387 0.064516 0.016129 0.000000 0.000000 0.000000 0.080645 0.112903 0.032258 0.032258 0.096774 0.064516 0.112903 0.000000 0.096774 0.016129 0.064516 0.032258 0.000000 0.000000 0.000000 0.016129 0.161290 0.000000 0.161290 0.000000 0.000000 0.032258 0.000000 0.596774 0.096774 0.000000 0.129032 0.000000 0.000000 0.000000 0.000000 0.000000 0.129032 0.000000 0.000000 0.000000 0.000000 0.000000 0.016129 0.000000 0.000000 0.016129 0.145161 0.048387 0.016129 0.048387 0.000000 0.129032 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.016129 0.032258 0.000000 0.000000 0.000000 0.548387 0.032258 0.000000 0.016129 0.048387 0.000000 0.032258 0.000000 0.274194 0.016129 0.048387 0.032258 0.080645 0.000000 0.000000 0.000000 0.177419 0.145161 0.080645 0.000000 0.016129 0.016129 0.516129 0.016129 0.016129 0.064516 0.016129 0.000000 0.032258 0.000000 0.000000 0.000000 0.080645 0.000000 0.000000 0.000000 0.064516 0.000000 0.000000 0.000000 0.177419 0.112903 0.016129 0.032258 0.016129 0.016129 0.000000 0.000000 0.016129 0.000000 0.064516 0.000000 0.000000 0.032258 0.016129 0.016129 0.580645 0.048387 0.000000 0.000000 0.032258 0.016129 0.000000 0.080645 0.612903 0.000000 0.080645 0.016129 0.000000 0.016129 0.016129 0.000000 0.000000 0.000000 0.080645 0.016129 0.016129 0.016129 0.016129 0.000000 0.016129 0.016129 0.112903 0.064516 0.048387 0.048387 0.000000 0.096774 0.000000 0.016129 0.096774 0.000000 0.048387 0.000000 0.016129 0.000000 0.000000 0.000000 0.016129 0.000000 0.419355 0.112903 0.016129 0.032258 0.112903 0.000000 0.500000 0.000000 0.000000 0.000000 0.000000 0.032258 0.016129 0.000000 0.016129 0.112903 0.000000 0.016129 0.016129 0.000000 0.016129 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif NLEEHLLEFGSHVDYICSEYG MEME-6 regular expression -------------------------------------------------------------------------------- NL[ED]E[HQ]LLE[FL][GE][SN]HXDYICSEYG -------------------------------------------------------------------------------- Time 244.64 secs. ******************************************************************************** ******************************************************************************** MOTIF KHKCWDRS MEME-7 width = 8 sites = 103 llr = 1411 E-value = 1.8e-257 ******************************************************************************** -------------------------------------------------------------------------------- Motif KHKCWDRS MEME-7 Description -------------------------------------------------------------------------------- Simplified A :::::::1 pos.-specific C :::81::: probability D :::::3:: matrix E :::::21: F :::11::: G :::::111 H :9::::1: I :::::::: K a:5::11: L ::::1::: M :::::::: N :::::1:1 P :::::::: Q ::::::2: R ::::1:31 S ::::1::3 T :::::::: V ::2::1:: W ::::4::: Y :::::::: bits 6.8 6.1 5.4 4.8 Relative 4.1 ** * Entropy 3.4 ** * (19.8 bits) 2.7 ** ** 2.0 ** ** 1.4 ***** * 0.7 ******** 0.0 -------- Multilevel KHKCWDRS consensus Q sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KHKCWDRS MEME-7 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- XP_018841755.1 44 7.16e-12 QAGQSDLPIP KHKCWDRS FASEPVFVFE XP_028773013.1 69 3.11e-11 QIDQLDMLRP KHKCWVRS FPSEEASILD TKS09656.1 44 4.33e-11 QDEQLGLPIS KHKCWDHR LPLKNSTICE TKR66562.1 41 4.33e-11 RAEQLGLPIS KHKCWDHR FPLKTSKICE XP_002531564.2 45 4.33e-11 QAEQLVLPIS KHKCWDHR IIYRPPSILE PKI39361.1 44 8.48e-11 EVEQLDLPSA KHKCWDQG CSTPVLAPCE XP_012832023.1 28 8.48e-11 QGEPMETPRP KHVCWDQR ADHGSSSCSV XP_028119329.1 44 8.48e-11 QAGQSSLPLP KHKCWDRT SSSESQSNEN PSS34997.1 44 8.48e-11 QAELLGLPLP KHKCWERS FSSEYDSPSN XP_028783417.1 44 1.57e-10 QTEQLDLPRQ KHKCWARR FSCENGSTSD XP_015960799.1 44 4.76e-10 QSDQLDLVRP KHKCWVGS FCSKHASTSD XP_017416333.1 50 4.76e-10 QSDQLDLLRP KHKCWVGS YSPGHASMFD TKY66008.1 44 4.76e-10 QIDQLDLLRP KHKCWVGS FSSEHASMFD XP_007134047.1 44 8.04e-10 QSNQLDLLRP KHKCWVGN SSSEHASSFD XP_008240727.1 39 9.64e-10 QAEQLGLPIP KHKCWERI FPSDEPVSMF OMO66336.1 41 1.33e-09 EAENLGLPIS KHQCWNRS LELKPPAFSG XP_011077640.1 87 1.33e-09 QAELQEMPLP KHVCWGHS LESDSLLASS XP_021289458.1 42 1.33e-09 EAEQLGLPIS KHQCWNRS LPSKPPTFSS XP_010047842.1 28 1.55e-09 QPELLVLPLP KHQCWDQG TIQFSTFNKH XP_021622766.1 21 1.55e-09 QAEQFGLPFP KHKCWDNH SSPKTLSILE XP_021650240.1 31 1.55e-09 QADQFGLPFP KHKCWDNH SSPKTLPMLE XP_024028595.1 39 2.21e-09 LAEQLGLPIL KHKCRDQA VSSDGPNTIF XP_012850185.1 33 2.67e-09 QDELLELPLL KHVCWHQN PELVFSSNNA XP_022747248.1 38 2.67e-09 GAELLGLPVS KHQCWKRS LSSKPPTFGG XP_004302767.1 42 3.16e-09 QAEQLGLPTP KHKCWDLN FPSDGPVSMF XP_024189435.1 44 3.16e-09 QAEQLGLPVP KHKCWDLN FPSDEHVSMF RVW33794.1 49 3.16e-09 QAELLDLPLP KHKCCGRS FSSQIVYPLD XP_012442486.1 79 4.33e-09 EAEQLGLPLS KHQCWKQS SSLKPPTFGS PSS23773.1 18 4.99e-09 QGEQLGLPPP KHYCWDQS LSSESDSPSN PON90845.1 39 6.95e-09 QAEQLGLPTR KQKCWDRA VASDGPFPKF PIN03316.1 34 8.00e-09 RNELLEMPLP KHICWGQN TDYDSSSNSS XP_027353450.1 44 9.28e-09 QTDQLDLLRP KHKCWLGS FSSEHASMFN RXI02216.1 54 1.43e-08 HEEQLGLPPP KHRCWARV FPSDESVSMF XP_027336786.1 44 1.43e-08 QSDELDLPRP KHKCWLGN SSSEHASMFE TKY63306.1 49 1.65e-08 QSDQLDFLRP KHRCWVGN SSSEHALIFD XP_023913884.1 44 1.65e-08 HAEQLGLPIP KHGCWDHS FASEDVTVFE XP_022742854.1 42 1.65e-08 EAEQLVLPVS KHHCWKQS LSLKPPTFGS TEY25303.1 34 2.53e-08 QDELLVMPLW KHACWDYR LVSEFPSDST PIN04755.1 34 2.89e-08 QAELLEMPCP KHVCFGQR LEYDASSDSS XP_012074964.1 45 2.89e-08 QAEQFGLPMP KLKCWDHR LSPKSIDENQ OAY41326.1 21 3.32e-08 QAEQFGLPFP KHKCWQKI ATVLLEILTM XP_019459351.1 46 3.80e-08 QSDQSDLLRP KHKCRVGH LSSEHTSMFD PNX96427.1 29 4.41e-08 QGFQLDLIRP KHKCRVES SSSEDESMID XP_013448883.1 46 4.41e-08 QGFQLDMLRP KHKCRVES FSSEDTSMSD XP_015896979.1 39 5.78e-08 QAEQLELPMA KHKCWQSS PSNESVSMSI XP_010037822.1 42 7.51e-08 LSEHCELPLP KHKCLDGG FDPVLLSEYD XP_018806280.1 44 1.27e-07 QAEQLDLPKP KHKFCARS FACEPVSVFE XP_008803152.1 120 1.62e-07 ELDDLGLPSP KHKFRDRF NTSGHGSLTA XP_010528448.1 49 1.62e-07 TEQLELLPLP KHVCFDEN KNKNSSDPSP TEY72131.1 79 1.83e-07 QDSQPEKHLA KHVCREKV EGDEPAKGCE RWR86109.1 33 1.83e-07 QGEQLGMPSP KHKFRDRC CSAEIKSPTT XP_021856950.1 27 2.06e-07 AASDLGLPAP KHVCCEAA NRSECDSSFF KFK36656.1 55 2.06e-07 QSELSLLPLS KHVCFDNV ACSDNSNVIS VDD15356.1 243 2.34e-07 RSELSLLPLS KHACFDKA AFSDNTNGRS KZV44349.1 34 2.65e-07 RREPVGVPLP KHVRWGQV VEHDLSSDSD XP_010678090.1 44 2.65e-07 AVEDFGLPAP KHVCCDPP VRTQCDLVFL XP_020553487.1 34 2.97e-07 HVELLGGPSP KHLCWGKK FEYESSSDSG XP_006398684.1 48 3.76e-07 AEESDLLPLP KHFCLEQA AHPDSSCPSS XP_019162543.1 45 3.76e-07 RAEQLGMPLP KHMCADQS FVTRYSSLVN OUZ99277.1 31 3.76e-07 QDEQSDLPSP KHKFREKR SAGSKQESPF XP_006410959.1 54 3.76e-07 QSELSLLPLS KHACFDNA TCSDNTNGRS OVA17828.1 47 3.76e-07 EDDELGLPQP KHKYRDQS SSSEQEEHFF XP_021744044.1 27 4.21e-07 AADDLGLPAP KHVCCEVA DSRSECGSSL XP_022846646.1 39 4.75e-07 QDEQLIMPLP KHICSNRS LECNSEPCLT PKI43461.1 48 4.75e-07 QSELLGLPTP KHTCLGRG SAPSCSTFQG GAV76568.1 44 5.33e-07 QAEQLGLPTP KHKFSNRS LLSELTSIFE XP_024982170.1 36 5.33e-07 HHGSLDLPVS KHACFEKS SNAETCFPSN PHT70537.1 58 5.33e-07 QAEQLGMPLP KHVCSYHS SAECSSSHPG XP_026417177.1 45 5.97e-07 EDDQVDLPSP KHKCGEPA SEQGGGLSED RID43060.1 48 7.44e-07 AEESDLLPLP KHFCLEQQ QALLPDSSSP XP_010937591.1 67 1.03e-06 ELDDLGLPSP KHKFGDRF NTSGRGSLTE XP_023734875.1 38 1.28e-06 QNEDFNLPVS KHTCLEKS VSPSNFQSDI OAO95598.1 48 1.28e-06 AEESYLLPLP KHFCSEQQ ASLVDSSRPS XP_006349495.1 46 1.42e-06 QAEQLGMPLP KHMCSYQS SAECNSSHTG XP_017215985.1 44 1.57e-06 QVEQLDLPLP KHNCCKKG ITSELRVSST KFK24705.1 29 1.57e-06 AEESDLLPLP KHFCMEQQ QASLSDSSCP XP_022983598.1 43 1.93e-06 PAEHLGLPSS KHKHCNEG FPSKLAFLYN XP_009798034.1 44 2.14e-06 QAEQLGIPLP KHLCSYQS YAGCSSSPTG XP_021741222.1 27 2.37e-06 AAEDFGLPAP KHVCYEAA DESECGSLRS XP_020108001.1 47 2.61e-06 ELNDSELPVS KHKFRFRD GLNSFNHESA XP_010256878.1 44 2.88e-06 LQEHLNLPLS KHKFGIRS SSSEHEYPFP AAL35819.1 59 3.18e-06 SDELSLLPLS KHTCFANV ACSENTNGNS XP_021691173.1 51 4.25e-06 QAEQFGLPVP KRNCWDHD SSPKPLLILE GAY47919.1 76 4.67e-06 QAEHLGLPIA KLKCSDGS FRSKSLSTLD RAL39303.1 30 5.13e-06 EAQQFGLPLP KHLCACQT FLRKYGSLLE XP_023544624.1 49 5.63e-06 LFEQLSLPTP KLPCWGPS SSSISFPYGE XP_004514391.1 46 5.63e-06 HGYQLDLLRP KNKCRVEN VSSEGASMLN OEL29447.1 159 6.17e-06 ELVDPRLLSL KYKFRNRL SRQEDDSATT RLN19347.1 63 6.17e-06 ELVDPSLLSL KYKFRNRL SRQEDDSATT EEC74952.1 66 6.17e-06 ELSDTRVSSL KYKFRNRL AWQEDESSRT ADE76868.1 132 6.77e-06 SGNSCISEYS KHICHEIS CSPNQSCRPP XP_022948410.1 34 7.42e-06 PAEHLGLPSP KHKHSNEA SPSKSVFLHD XP_010529822.1 49 8.88e-06 TDQFDSSPLP KHVCFHDK GEASLSKSCE XP_010543288.1 45 9.70e-06 LDGVLELPLP KHVRLEQT SIDDPCSPLD XP_010558336.1 42 1.06e-05 LAEVLELPLR KQVCHKQT SLADPCSPLG XP_022145567.1 44 1.16e-05 PAEHLGLPSP KHKHCSEG FPSKSAFPYS XP_008448098.1 63 1.26e-05 LIDQLSLPTS KLPCWGSR SISIPHGEDN VAI07274.1 64 1.50e-05 DLSDTRLSSL KYKFQDRP TSQEDETART XP_020268040.1 43 1.78e-05 ELENSDSPLL KHRNCDRY GSSDHPQIIT XP_022039957.1 66 2.11e-05 DEISEELPVA KHTCLCLD ISSSSSAKDS XP_014752653.1 52 2.70e-05 ELSDTRLSSL KYKFQNRL TCQEDESART XP_004137783.2 135 4.73e-05 PAEHLGLPSP KHKHCSEE FASKSAFLYG PWA88889.1 5 1.01e-04 MPKP KQACLKCQ CSQGEGEGDS -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KHKCWDRS MEME-7 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- XP_018841755.1 7.2e-12 43_[7]_171 XP_028773013.1 3.1e-11 68_[7]_205 TKS09656.1 4.3e-11 43_[7]_210 TKR66562.1 4.3e-11 40_[7]_209 XP_002531564.2 4.3e-11 44_[7]_209 PKI39361.1 8.5e-11 43_[7]_212 XP_012832023.1 8.5e-11 27_[7]_159 XP_028119329.1 8.5e-11 43_[7]_190 PSS34997.1 8.5e-11 43_[7]_210 XP_028783417.1 1.6e-10 43_[7]_156 XP_015960799.1 4.8e-10 43_[7]_138 XP_017416333.1 4.8e-10 49_[7]_175 TKY66008.1 4.8e-10 43_[7]_175 XP_007134047.1 8e-10 43_[7]_200 XP_008240727.1 9.6e-10 38_[7]_185 OMO66336.1 1.3e-09 40_[7]_201 XP_011077640.1 1.3e-09 86_[7]_191 XP_021289458.1 1.3e-09 41_[7]_204 XP_010047842.1 1.6e-09 27_[7]_208 XP_021622766.1 1.6e-09 20_[7]_209 XP_021650240.1 1.6e-09 30_[7]_211 XP_024028595.1 2.2e-09 38_[7]_190 XP_012850185.1 2.7e-09 32_[7]_164 XP_022747248.1 2.7e-09 37_[7]_204 XP_004302767.1 3.2e-09 41_[7]_207 XP_024189435.1 3.2e-09 43_[7]_207 RVW33794.1 3.2e-09 48_[7]_204 XP_012442486.1 4.3e-09 78_[7]_196 PSS23773.1 5e-09 17_[7]_178 PON90845.1 6.9e-09 38_[7]_199 PIN03316.1 8e-09 33_[7]_169 XP_027353450.1 9.3e-09 43_[7]_184 RXI02216.1 1.4e-08 53_[7]_196 XP_027336786.1 1.4e-08 43_[7]_202 TKY63306.1 1.7e-08 48_[7]_206 XP_023913884.1 1.7e-08 43_[7]_194 XP_022742854.1 1.7e-08 41_[7]_204 TEY25303.1 2.5e-08 33_[7]_202 PIN04755.1 2.9e-08 33_[7]_186 XP_012074964.1 2.9e-08 44_[7]_205 OAY41326.1 3.3e-08 20_[7]_167 XP_019459351.1 3.8e-08 45_[7]_185 PNX96427.1 4.4e-08 28_[7]_179 XP_013448883.1 4.4e-08 45_[7]_160 XP_015896979.1 5.8e-08 38_[7]_200 XP_010037822.1 7.5e-08 41_[7]_208 XP_018806280.1 1.3e-07 43_[7]_194 XP_008803152.1 1.6e-07 119_[7]_212 XP_010528448.1 1.6e-07 48_[7]_124 TEY72131.1 1.8e-07 78_[7]_163 RWR86109.1 1.8e-07 32_[7]_213 XP_021856950.1 2.1e-07 26_[7]_170 KFK36656.1 2.1e-07 54_[7]_135 VDD15356.1 2.3e-07 242_[7]_130 KZV44349.1 2.6e-07 33_[7]_146 XP_010678090.1 2.6e-07 43_[7]_177 XP_020553487.1 3e-07 33_[7]_203 XP_006398684.1 3.8e-07 47_[7]_147 XP_019162543.1 3.8e-07 44_[7]_192 OUZ99277.1 3.8e-07 30_[7]_191 XP_006410959.1 3.8e-07 53_[7]_130 OVA17828.1 3.8e-07 46_[7]_214 XP_021744044.1 4.2e-07 26_[7]_172 XP_022846646.1 4.7e-07 38_[7]_199 PKI43461.1 4.7e-07 47_[7]_186 GAV76568.1 5.3e-07 43_[7]_213 XP_024982170.1 5.3e-07 35_[7]_196 PHT70537.1 5.3e-07 57_[7]_207 XP_026417177.1 6e-07 44_[7]_191 RID43060.1 7.4e-07 47_[7]_141 XP_010937591.1 1e-06 66_[7]_206 XP_023734875.1 1.3e-06 37_[7]_165 OAO95598.1 1.3e-06 47_[7]_146 XP_006349495.1 1.4e-06 45_[7]_207 XP_017215985.1 1.6e-06 43_[7]_202 KFK24705.1 1.6e-06 28_[7]_138 XP_022983598.1 1.9e-06 42_[7]_203 XP_009798034.1 2.1e-06 43_[7]_208 XP_021741222.1 2.4e-06 26_[7]_171 XP_020108001.1 2.6e-06 46_[7]_192 XP_010256878.1 2.9e-06 43_[7]_210 AAL35819.1 3.2e-06 58_[7]_136 XP_021691173.1 4.2e-06 50_[7]_194 GAY47919.1 4.7e-06 75_[7]_201 RAL39303.1 5.1e-06 29_[7]_174 XP_023544624.1 5.6e-06 48_[7]_137 XP_004514391.1 5.6e-06 45_[7]_185 OEL29447.1 6.2e-06 158_[7]_193 RLN19347.1 6.2e-06 62_[7]_193 EEC74952.1 6.2e-06 65_[7]_192 ADE76868.1 6.8e-06 131_[7]_262 XP_022948410.1 7.4e-06 33_[7]_188 XP_010529822.1 8.9e-06 48_[7]_143 XP_010543288.1 9.7e-06 44_[7]_148 XP_010558336.1 1.1e-05 41_[7]_188 XP_022145567.1 1.2e-05 43_[7]_197 XP_008448098.1 1.3e-05 62_[7]_131 VAI07274.1 1.5e-05 63_[7]_178 XP_020268040.1 1.8e-05 42_[7]_124 XP_022039957.1 2.1e-05 65_[7]_109 XP_014752653.1 2.7e-05 51_[7]_187 XP_004137783.2 4.7e-05 134_[7]_205 PWA88889.1 0.0001 4_[7]_126 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KHKCWDRS MEME-7 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF KHKCWDRS width=8 seqs=103 XP_018841755.1 ( 44) KHKCWDRS 1 XP_028773013.1 ( 69) KHKCWVRS 1 TKS09656.1 ( 44) KHKCWDHR 1 TKR66562.1 ( 41) KHKCWDHR 1 XP_002531564.2 ( 45) KHKCWDHR 1 PKI39361.1 ( 44) KHKCWDQG 1 XP_012832023.1 ( 28) KHVCWDQR 1 XP_028119329.1 ( 44) KHKCWDRT 1 PSS34997.1 ( 44) KHKCWERS 1 XP_028783417.1 ( 44) KHKCWARR 1 XP_015960799.1 ( 44) KHKCWVGS 1 XP_017416333.1 ( 50) KHKCWVGS 1 TKY66008.1 ( 44) KHKCWVGS 1 XP_007134047.1 ( 44) KHKCWVGN 1 XP_008240727.1 ( 39) KHKCWERI 1 OMO66336.1 ( 41) KHQCWNRS 1 XP_011077640.1 ( 87) KHVCWGHS 1 XP_021289458.1 ( 42) KHQCWNRS 1 XP_010047842.1 ( 28) KHQCWDQG 1 XP_021622766.1 ( 21) KHKCWDNH 1 XP_021650240.1 ( 31) KHKCWDNH 1 XP_024028595.1 ( 39) KHKCRDQA 1 XP_012850185.1 ( 33) KHVCWHQN 1 XP_022747248.1 ( 38) KHQCWKRS 1 XP_004302767.1 ( 42) KHKCWDLN 1 XP_024189435.1 ( 44) KHKCWDLN 1 RVW33794.1 ( 49) KHKCCGRS 1 XP_012442486.1 ( 79) KHQCWKQS 1 PSS23773.1 ( 18) KHYCWDQS 1 PON90845.1 ( 39) KQKCWDRA 1 PIN03316.1 ( 34) KHICWGQN 1 XP_027353450.1 ( 44) KHKCWLGS 1 RXI02216.1 ( 54) KHRCWARV 1 XP_027336786.1 ( 44) KHKCWLGN 1 TKY63306.1 ( 49) KHRCWVGN 1 XP_023913884.1 ( 44) KHGCWDHS 1 XP_022742854.1 ( 42) KHHCWKQS 1 TEY25303.1 ( 34) KHACWDYR 1 PIN04755.1 ( 34) KHVCFGQR 1 XP_012074964.1 ( 45) KLKCWDHR 1 OAY41326.1 ( 21) KHKCWQKI 1 XP_019459351.1 ( 46) KHKCRVGH 1 PNX96427.1 ( 29) KHKCRVES 1 XP_013448883.1 ( 46) KHKCRVES 1 XP_015896979.1 ( 39) KHKCWQSS 1 XP_010037822.1 ( 42) KHKCLDGG 1 XP_018806280.1 ( 44) KHKFCARS 1 XP_008803152.1 ( 120) KHKFRDRF 1 XP_010528448.1 ( 49) KHVCFDEN 1 TEY72131.1 ( 79) KHVCREKV 1 RWR86109.1 ( 33) KHKFRDRC 1 XP_021856950.1 ( 27) KHVCCEAA 1 KFK36656.1 ( 55) KHVCFDNV 1 VDD15356.1 ( 243) KHACFDKA 1 KZV44349.1 ( 34) KHVRWGQV 1 XP_010678090.1 ( 44) KHVCCDPP 1 XP_020553487.1 ( 34) KHLCWGKK 1 XP_006398684.1 ( 48) KHFCLEQA 1 XP_019162543.1 ( 45) KHMCADQS 1 OUZ99277.1 ( 31) KHKFREKR 1 XP_006410959.1 ( 54) KHACFDNA 1 OVA17828.1 ( 47) KHKYRDQS 1 XP_021744044.1 ( 27) KHVCCEVA 1 XP_022846646.1 ( 39) KHICSNRS 1 PKI43461.1 ( 48) KHTCLGRG 1 GAV76568.1 ( 44) KHKFSNRS 1 XP_024982170.1 ( 36) KHACFEKS 1 PHT70537.1 ( 58) KHVCSYHS 1 XP_026417177.1 ( 45) KHKCGEPA 1 RID43060.1 ( 48) KHFCLEQQ 1 XP_010937591.1 ( 67) KHKFGDRF 1 XP_023734875.1 ( 38) KHTCLEKS 1 OAO95598.1 ( 48) KHFCSEQQ 1 XP_006349495.1 ( 46) KHMCSYQS 1 XP_017215985.1 ( 44) KHNCCKKG 1 KFK24705.1 ( 29) KHFCMEQQ 1 XP_022983598.1 ( 43) KHKHCNEG 1 XP_009798034.1 ( 44) KHLCSYQS 1 XP_021741222.1 ( 27) KHVCYEAA 1 XP_020108001.1 ( 47) KHKFRFRD 1 XP_010256878.1 ( 44) KHKFGIRS 1 AAL35819.1 ( 59) KHTCFANV 1 XP_021691173.1 ( 51) KRNCWDHD 1 GAY47919.1 ( 76) KLKCSDGS 1 RAL39303.1 ( 30) KHLCACQT 1 XP_023544624.1 ( 49) KLPCWGPS 1 XP_004514391.1 ( 46) KNKCRVEN 1 OEL29447.1 ( 159) KYKFRNRL 1 RLN19347.1 ( 63) KYKFRNRL 1 EEC74952.1 ( 66) KYKFRNRL 1 ADE76868.1 ( 132) KHICHEIS 1 XP_022948410.1 ( 34) KHKHSNEA 1 XP_010529822.1 ( 49) KHVCFHDK 1 XP_010543288.1 ( 45) KHVRLEQT 1 XP_010558336.1 ( 42) KQVCHKQT 1 XP_022145567.1 ( 44) KHKHCSEG 1 XP_008448098.1 ( 63) KLPCWGSR 1 VAI07274.1 ( 64) KYKFQDRP 1 XP_020268040.1 ( 43) KHRNCDRY 1 XP_022039957.1 ( 66) KHTCLCLD 1 XP_014752653.1 ( 52) KYKFQNRL 1 XP_004137783.2 ( 135) KHKHCSEE 1 PWA88889.1 ( 5) KQACLKCQ 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KHKCWDRS MEME-7 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 20 w= 8 n= 27745 bayes= 7.92875 E= 1.8e-257 -956 -931 -1011 -1123 -998 -860 -921 -1059 410 -1017 -1100 -1018 -894 -989 -836 -1106 -973 -1031 -858 -980 -420 -441 -448 -516 -365 -484 500 -491 -505 -125 -400 -174 -464 -34 -140 -477 -381 -433 -316 43 12 -471 -483 -439 -6 -227 -126 -35 300 -126 -44 -139 -103 25 -19 -480 -18 181 -436 -164 -766 523 -917 -948 169 -824 60 -676 -821 -646 -686 -249 -820 -728 -85 -870 -758 -676 -351 -111 -104 215 -669 -620 94 -90 -42 -261 -521 6 -119 -551 -548 -107 190 -78 -366 -246 550 -161 -15 -18 200 61 -197 63 -34 -190 9 -189 -424 77 -437 -80 -274 -242 -323 110 -464 -22 -94 -114 -248 -32 -513 78 153 -190 46 -137 -424 -16 -47 230 283 -242 -323 -188 -465 -166 104 -114 -126 -255 -105 28 19 -102 -115 -100 -424 62 -101 1 145 121 -18 15 -465 -166 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KHKCWDRS MEME-7 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 20 w= 8 nsites= 103 E= 1.8e-257 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.864078 0.000000 0.000000 0.038835 0.000000 0.009709 0.000000 0.029126 0.009709 0.000000 0.000000 0.000000 0.000000 0.048544 0.048544 0.000000 0.000000 0.000000 0.038835 0.009709 0.009709 0.029126 0.495146 0.029126 0.019417 0.019417 0.019417 0.048544 0.029126 0.000000 0.038835 0.155340 0.000000 0.009709 0.000000 0.796117 0.000000 0.000000 0.126214 0.000000 0.038835 0.000000 0.000000 0.000000 0.000000 0.009709 0.000000 0.000000 0.019417 0.000000 0.000000 0.000000 0.000000 0.009709 0.019417 0.097087 0.000000 0.000000 0.077670 0.029126 0.019417 0.000000 0.000000 0.077670 0.009709 0.000000 0.000000 0.019417 0.135922 0.077670 0.000000 0.000000 0.427184 0.009709 0.038835 0.019417 0.320388 0.155340 0.009709 0.087379 0.019417 0.009709 0.058252 0.019417 0.000000 0.097087 0.000000 0.019417 0.000000 0.019417 0.000000 0.097087 0.000000 0.029126 0.019417 0.009709 0.009709 0.077670 0.000000 0.097087 0.077670 0.009709 0.077670 0.029126 0.000000 0.048544 0.029126 0.213592 0.262136 0.019417 0.000000 0.009709 0.000000 0.009709 0.097087 0.009709 0.029126 0.009709 0.019417 0.067961 0.029126 0.019417 0.019417 0.038835 0.000000 0.087379 0.019417 0.038835 0.097087 0.320388 0.038835 0.048544 0.000000 0.009709 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KHKCWDRS MEME-7 regular expression -------------------------------------------------------------------------------- KHKCWD[RQ]S -------------------------------------------------------------------------------- Time 275.87 secs. ******************************************************************************** ******************************************************************************** MOTIF SAMSVYGEAKLEAEY MEME-8 width = 15 sites = 61 llr = 1200 E-value = 5.4e-180 ******************************************************************************** -------------------------------------------------------------------------------- Motif SAMSVYGEAKLEAEY MEME-8 Description -------------------------------------------------------------------------------- Simplified A :6::::::6:::3:: pos.-specific C ::::::::::::::1 probability D ::::::11:::1:21 matrix E ::::::27:1:5:4: F :::::1::::2:::1 G ::::::211::1:1: H :::::1::::::::: I ::2:1:::::::::1 K :::::::::8::::: L ::::::::::3:2:: M ::6:::::::::::: N :::::21::::::1: P ::::::::::::2:: Q :::::::::::1::: R ::::::::::::::: S 62:9:1::1:::::1 T 2:2:::::1:1:2:: V :1::7:::1:11::1 W ::::::::::::::: Y :::::41:::::::2 bits 6.8 6.1 5.4 4.8 Relative 4.1 Entropy 3.4 * (28.4 bits) 2.7 *** * 2.0 ****** *** * 1.4 ****** ******** 0.7 *************** 0.0 --------------- Multilevel SAMSVYGEAKLEAEY consensus T F TD sequence P -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SAMSVYGEAKLEAEY MEME-8 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- --------------- RVW33794.1 109 9.33e-15 DSNSLAGYSD SVISVYGEAKFEPEC EKTCPYNYPY XP_027353450.1 104 1.29e-14 DSNSFIDDFD TAMSVNEEAKHEADC GNAYLYVNRI TKY66008.1 94 1.51e-14 DSNSFIEDCD TAMSVNEEAKHEPDC GNSYLYVNRV XP_008240727.1 100 2.41e-14 GSNSFAGDSD SATSVYVEAKLEPVY ARACLNDRPS XP_002531564.2 105 1.04e-13 DSNSFVGDSE SIMSVHGEAKFETEV SKQWPPLNGP TKS09656.1 104 2.08e-13 DSNSFVGDSD SAMSVSGEAKLEMEV SKIWSSDRPS XP_021622766.1 81 3.12e-13 DSNSFVGDSD HVMSVYGEAKFETEV SKPGLSNEPS XP_023913884.1 105 5.28e-13 GSNSFAEDSD SAMSIYDEARLQPEY ANTHLSDGPS XP_022747248.1 95 1.45e-12 DSNSFAKDSD SAMSVHAEAKFRTED ANYLQYDRSS XP_024028595.1 97 2.10e-12 DSNSYTEDSN SSTSIYGEAKMEAEY ATTPHYSLVS XP_021289458.1 99 2.10e-12 DSNSFSEDSD YAMSVHYEAKFGTED TKYLLYGRAS GAV76568.1 104 6.82e-12 DSNSFVDDSD SAMSVYGENKLEIED TKPSSCDRPS PON90845.1 93 6.82e-12 DSNSFAEVSD SATSAYNGAKMEAEY VKIYYSPSSS XP_024189435.1 107 7.64e-12 SNSFAGDYCD SAMSVYSEAELNAAY AKSIYDRPST XP_004514391.1 106 9.59e-12 DSNSFIEDSD TSMSVNEEAKPDADC ANAYLCVNRL XP_022145567.1 104 1.07e-11 DSNSLSEEAD SATSVFRGAKFEPSC DSSSSQSISC XP_027336786.1 100 1.07e-11 DSNSFTEDSN TAMSVNEEGKLVADS AKTYLYGGPS XP_007134047.1 100 1.07e-11 DSNSLSQDSI TAMSVNEEGKLVADS AMTYQDGRPA TKR66562.1 101 1.20e-11 DSNSFVEDSD FAMSVDGEAKFEMEV SKIWPPDRPS OAY41326.1 38 1.34e-11 IATVLLEILT MFMSVYGEAKFDTEV SKPGLSNEPC PNX96427.1 89 1.87e-11 DSNSFIEDSD TSMSVNDDAKLEADS ANTSLCVNRL XP_015960799.1 104 1.87e-11 DSNSFMEDSD TAISVNKEAKLDADT YLYGHAYSED XP_015896979.1 99 2.59e-11 DSNSFFGDSD SPTSIYVEAKVEPEY VKTYLYDMPS XP_013448883.1 106 3.21e-11 DSNSFIEDSD TSMSINEEAKLEADS ANTYSSYDDL XP_028783417.1 81 3.57e-11 GSNSFGEDSD TAISVNEEGKLQIDC AKPYLHGRPS XP_004137783.2 195 3.97e-11 DSNSLSEESD SATSVFHGAKFELNQ AITCTHDTST XP_022983598.1 103 3.97e-11 DSNSFCEESD SATSVFHGAKFELNQ ACTYDSSSTQ XP_028119329.1 102 4.41e-11 DSNSFGGNSD SAMSISGEAKIQLEF FKNSLYSLES XP_022742854.1 99 7.42e-11 DSNSFAEDSD SAISVHAEVKFGTDD AKYLPYDRAS XP_022948410.1 94 9.11e-11 DSNSFSDESN SATSVFCGAKLELNQ ALSCTRDSSE RXI02216.1 115 1.36e-10 GSNSFARDSG YATSVYGDSKVGPVY AQTCQYDRPS XP_017416333.1 100 2.24e-10 DSNSFMEDSD TAVSVNKEANHETDC ENSYLYVNRM OVA17828.1 96 3.63e-10 ESPNASTSFD SAISPYPEAKYEREF LKVYTYNQPD XP_012074964.1 101 5.31e-10 DSNSFIGDSD SATSLYYDSKLETEI SKEWPCNGPS XP_019459351.1 106 5.84e-10 DNNSFIEESD TSMSVNEEAKVEEEG TNTYLYVKSV XP_004302767.1 105 8.47e-10 SNSFAGDYCD SAISVYREVEPNPAY AKSVCDRPST XP_028773013.1 129 8.47e-10 DSNSFAEDSD ASMSVYEEVRLEADS AKTFLYGRPS XP_018841755.1 104 9.29e-10 DSNSFGGDSN SATSSYDEAKVQLEK DKLAFLSGEH XP_021650240.1 91 1.12e-09 DSNSFVGDCD SAMSVYGEGEVKFET EVSKLGPSNG XP_011077640.1 138 1.75e-09 DSNSFHCNED SIMSIDYESKTETEC PETSAASYER XP_026417177.1 80 2.50e-09 PSGSNYFNSA TAMSSYPDPKLEPNF LKVYTYNKPA TKY63306.1 105 3.86e-09 DINSFSEDSI TVNSVNEEGKLVADS AKTYQYGRPS XP_023734875.1 78 7.62e-09 DSNNFFEDAD SVMSVYNDSENELPY LKISPYDHHS XP_012442486.1 136 8.29e-09 DSNSFADDSD TAISVHVDAKYLLYN RASSSSSPNW XP_024982170.1 97 1.25e-08 DSNSFSEDAD SVMSVSIDSKNELHY LKICPPDQNS XP_010037822.1 102 1.73e-08 GSNSFSEDSD TATSAYGGFNLGPDI AVITSGASTS PKI39361.1 109 1.88e-08 GSNSFTEDAD SEMSVHDETSLETKY EKFNDRPSTS XP_027149457.1 72 2.80e-08 DSNSVSADAD SSISVSSEAEVGAGH GYFKEYSSDM XP_020553487.1 85 4.47e-08 DSCSFHGDVD SIMSPCDDAKTYLSY SETRVSVQPC OUZ99277.1 74 5.21e-08 DSNSFVGENN SAISLYPADMFEPEF PKTYAYDQPS PIA54706.1 107 6.55e-08 DSNSFAEESD CAMSQYTEVKSEPEL SDVCIHEQPA GAY47919.1 131 7.06e-08 NSNIYAEGYD SSITVHGKSRFQAEI GESLPDDCPS XP_027176296.1 82 9.53e-08 DSNSIAADAD SSISVSNETEVGAGH GYFKEYSSDK TEY25303.1 85 1.28e-07 NSYCFPSDTD MSMSSHDDAKTYLSY PIAHASAKSC XP_022846646.1 86 2.46e-07 DRNSFTRDSD SVNSISGEAKSDLGS PKTFSSDQAS XP_017215985.1 103 2.64e-07 GSNSLVEDYD SVMSESYGTKNNTVY LNTLSVDCTS XP_010047842.1 86 3.04e-07 DSYSFVEYSD STMSLYGMDNCETES TSISNLYSGL XP_012832023.1 41 1.04e-06 CWDQRADHGS SSCSVTEQTKLVTKN LLGGSDAEFY KZV44349.1 76 1.75e-06 SINSLQSNIE STMFTCNEGKTDPGN PENRPSDESS XP_022143715.1 86 2.57e-06 VEEEEINLTK RAMEVKEISKLEALM ESGLHISYGH RWR86109.1 95 5.39e-06 SNSFIEESDT ATMPVDSEDKPSTEI GTNYLDWLSI -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SAMSVYGEAKLEAEY MEME-8 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- RVW33794.1 9.3e-15 108_[8]_137 XP_027353450.1 1.3e-14 103_[8]_117 TKY66008.1 1.5e-14 93_[8]_118 XP_008240727.1 2.4e-14 99_[8]_117 XP_002531564.2 1e-13 104_[8]_142 TKS09656.1 2.1e-13 103_[8]_143 XP_021622766.1 3.1e-13 80_[8]_142 XP_023913884.1 5.3e-13 104_[8]_126 XP_022747248.1 1.5e-12 94_[8]_140 XP_024028595.1 2.1e-12 96_[8]_125 XP_021289458.1 2.1e-12 98_[8]_140 GAV76568.1 6.8e-12 103_[8]_146 PON90845.1 6.8e-12 92_[8]_138 XP_024189435.1 7.6e-12 106_[8]_137 XP_004514391.1 9.6e-12 105_[8]_118 XP_022145567.1 1.1e-11 103_[8]_130 XP_027336786.1 1.1e-11 99_[8]_139 XP_007134047.1 1.1e-11 99_[8]_137 TKR66562.1 1.2e-11 100_[8]_142 OAY41326.1 1.3e-11 37_[8]_143 PNX96427.1 1.9e-11 88_[8]_112 XP_015960799.1 1.9e-11 103_[8]_71 XP_015896979.1 2.6e-11 98_[8]_133 XP_013448883.1 3.2e-11 105_[8]_93 XP_028783417.1 3.6e-11 80_[8]_112 XP_004137783.2 4e-11 194_[8]_138 XP_022983598.1 4e-11 102_[8]_136 XP_028119329.1 4.4e-11 101_[8]_125 XP_022742854.1 7.4e-11 98_[8]_140 XP_022948410.1 9.1e-11 93_[8]_121 RXI02216.1 1.4e-10 114_[8]_128 XP_017416333.1 2.2e-10 99_[8]_118 OVA17828.1 3.6e-10 95_[8]_158 XP_012074964.1 5.3e-10 100_[8]_142 XP_019459351.1 5.8e-10 105_[8]_118 XP_004302767.1 8.5e-10 104_[8]_137 XP_028773013.1 8.5e-10 128_[8]_138 XP_018841755.1 9.3e-10 103_[8]_104 XP_021650240.1 1.1e-09 90_[8]_144 XP_011077640.1 1.8e-09 137_[8]_133 XP_026417177.1 2.5e-09 79_[8]_149 TKY63306.1 3.9e-09 104_[8]_143 XP_023734875.1 7.6e-09 77_[8]_118 XP_012442486.1 8.3e-09 135_[8]_132 XP_024982170.1 1.3e-08 96_[8]_128 XP_010037822.1 1.7e-08 101_[8]_141 PKI39361.1 1.9e-08 108_[8]_140 XP_027149457.1 2.8e-08 71_[8]_146 XP_020553487.1 4.5e-08 84_[8]_145 OUZ99277.1 5.2e-08 73_[8]_141 PIA54706.1 6.5e-08 106_[8]_142 GAY47919.1 7.1e-08 130_[8]_139 XP_027176296.1 9.5e-08 81_[8]_146 TEY25303.1 1.3e-07 84_[8]_144 XP_022846646.1 2.5e-07 85_[8]_145 XP_017215985.1 2.6e-07 102_[8]_136 XP_010047842.1 3e-07 85_[8]_143 XP_012832023.1 1e-06 40_[8]_139 KZV44349.1 1.8e-06 75_[8]_97 XP_022143715.1 2.6e-06 85_[8]_69 RWR86109.1 5.4e-06 94_[8]_144 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SAMSVYGEAKLEAEY MEME-8 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF SAMSVYGEAKLEAEY width=15 seqs=61 RVW33794.1 ( 109) SVISVYGEAKFEPEC 1 XP_027353450.1 ( 104) TAMSVNEEAKHEADC 1 TKY66008.1 ( 94) TAMSVNEEAKHEPDC 1 XP_008240727.1 ( 100) SATSVYVEAKLEPVY 1 XP_002531564.2 ( 105) SIMSVHGEAKFETEV 1 TKS09656.1 ( 104) SAMSVSGEAKLEMEV 1 XP_021622766.1 ( 81) HVMSVYGEAKFETEV 1 XP_023913884.1 ( 105) SAMSIYDEARLQPEY 1 XP_022747248.1 ( 95) SAMSVHAEAKFRTED 1 XP_024028595.1 ( 97) SSTSIYGEAKMEAEY 1 XP_021289458.1 ( 99) YAMSVHYEAKFGTED 1 GAV76568.1 ( 104) SAMSVYGENKLEIED 1 PON90845.1 ( 93) SATSAYNGAKMEAEY 1 XP_024189435.1 ( 107) SAMSVYSEAELNAAY 1 XP_004514391.1 ( 106) TSMSVNEEAKPDADC 1 XP_022145567.1 ( 104) SATSVFRGAKFEPSC 1 XP_027336786.1 ( 100) TAMSVNEEGKLVADS 1 XP_007134047.1 ( 100) TAMSVNEEGKLVADS 1 TKR66562.1 ( 101) FAMSVDGEAKFEMEV 1 OAY41326.1 ( 38) MFMSVYGEAKFDTEV 1 PNX96427.1 ( 89) TSMSVNDDAKLEADS 1 XP_015960799.1 ( 104) TAISVNKEAKLDADT 1 XP_015896979.1 ( 99) SPTSIYVEAKVEPEY 1 XP_013448883.1 ( 106) TSMSINEEAKLEADS 1 XP_028783417.1 ( 81) TAISVNEEGKLQIDC 1 XP_004137783.2 ( 195) SATSVFHGAKFELNQ 1 XP_022983598.1 ( 103) SATSVFHGAKFELNQ 1 XP_028119329.1 ( 102) SAMSISGEAKIQLEF 1 XP_022742854.1 ( 99) SAISVHAEVKFGTDD 1 XP_022948410.1 ( 94) SATSVFCGAKLELNQ 1 RXI02216.1 ( 115) YATSVYGDSKVGPVY 1 XP_017416333.1 ( 100) TAVSVNKEANHETDC 1 OVA17828.1 ( 96) SAISPYPEAKYEREF 1 XP_012074964.1 ( 101) SATSLYYDSKLETEI 1 XP_019459351.1 ( 106) TSMSVNEEAKVEEEG 1 XP_004302767.1 ( 105) SAISVYREVEPNPAY 1 XP_028773013.1 ( 129) ASMSVYEEVRLEADS 1 XP_018841755.1 ( 104) SATSSYDEAKVQLEK 1 XP_021650240.1 ( 91) SAMSVYGEGEVKFET 1 XP_011077640.1 ( 138) SIMSIDYESKTETEC 1 XP_026417177.1 ( 80) TAMSSYPDPKLEPNF 1 TKY63306.1 ( 105) TVNSVNEEGKLVADS 1 XP_023734875.1 ( 78) SVMSVYNDSENELPY 1 XP_012442486.1 ( 136) TAISVHVDAKYLLYN 1 XP_024982170.1 ( 97) SVMSVSIDSKNELHY 1 XP_010037822.1 ( 102) TATSAYGGFNLGPDI 1 PKI39361.1 ( 109) SEMSVHDETSLETKY 1 XP_027149457.1 ( 72) SSISVSSEAEVGAGH 1 XP_020553487.1 ( 85) SIMSPCDDAKTYLSY 1 OUZ99277.1 ( 74) SAISLYPADMFEPEF 1 PIA54706.1 ( 107) CAMSQYTEVKSEPEL 1 GAY47919.1 ( 131) SSITVHGKSRFQAEI 1 XP_027176296.1 ( 82) SSISVSNETEVGAGH 1 TEY25303.1 ( 85) MSMSSHDDAKTYLSY 1 XP_022846646.1 ( 86) SVNSISGEAKSDLGS 1 XP_017215985.1 ( 103) SVMSESYGTKNNTVY 1 XP_010047842.1 ( 86) STMSLYGMDNCETES 1 XP_012832023.1 ( 41) SSCSVTEQTKLVTKN 1 KZV44349.1 ( 76) STMFTCNEGKTDPGN 1 XP_022143715.1 ( 86) RAMEVKEISKLEALM 1 RWR86109.1 ( 95) ATMPVDSEDKPSTEI 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SAMSVYGEAKLEAEY MEME-8 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 20 w= 15 n= 26933 bayes= 8.72728 E= 5.4e-180 -60 -77 -451 -523 -179 -369 -125 -384 -368 -429 -43 -271 -368 -395 -137 229 211 -390 -374 -69 372 -198 -504 -283 -157 -237 -426 -13 -414 -338 -306 -446 -175 -413 -352 6 -24 104 -349 -431 -411 -35 -796 -761 -479 -639 -640 219 -668 -373 428 -80 -656 -645 -608 -680 204 -62 -541 -557 -217 -320 -488 -288 -159 -389 -441 -436 -420 -480 -426 -318 -153 -441 -355 272 17 -424 -425 -454 -25 -236 -455 -308 -332 -403 -347 115 -388 -111 -263 -431 -115 -205 -295 -226 -116 405 -367 -450 -308 47 -66 -454 92 -391 219 -387 -173 -400 -398 165 -444 -395 -361 -33 -139 -365 -240 353 -26 -46 32 90 -444 203 34 -122 -46 -398 -356 23 22 -214 10 -128 -105 15 -396 86 -133 -874 97 269 -799 101 -531 -133 -163 -630 -80 -521 -523 -106 -483 -605 -488 -526 -737 -696 373 -191 -120 -475 -163 41 -424 -306 -409 -346 -310 -213 -180 -410 -347 -49 6 37 -349 -437 -453 -607 -644 -13 -696 -556 -413 -540 369 -550 -83 -26 -579 -334 69 -297 -463 -518 -521 -569 -270 -31 -632 -581 233 -465 84 -61 -480 201 34 -25 22 -447 -408 -194 51 146 -338 -2 -228 -484 9 227 -457 76 -285 -396 -111 -203 -368 -13 -377 98 -65 -243 -265 53 -409 -8 240 -349 -626 -256 -104 -465 -428 4 -475 119 34 -495 230 -444 -103 -495 223 -171 -338 -367 -26 -473 148 191 -447 20 -50 -387 -47 -201 -358 23 -119 -216 -208 -128 -256 15 -398 -98 -226 233 -44 -413 99 -172 40 56 -164 -170 -69 -38 -389 5 -287 -24 -52 78 -182 299 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SAMSVYGEAKLEAEY MEME-8 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 20 w= 15 nsites= 61 E= 5.4e-180 0.032787 0.016393 0.000000 0.000000 0.016393 0.000000 0.016393 0.000000 0.000000 0.000000 0.032787 0.000000 0.000000 0.000000 0.016393 0.590164 0.245902 0.000000 0.000000 0.032787 0.557377 0.000000 0.000000 0.016393 0.016393 0.000000 0.000000 0.049180 0.000000 0.000000 0.000000 0.000000 0.016393 0.000000 0.000000 0.180328 0.049180 0.114754 0.000000 0.000000 0.000000 0.016393 0.000000 0.000000 0.000000 0.000000 0.000000 0.180328 0.000000 0.000000 0.557377 0.032787 0.000000 0.000000 0.000000 0.000000 0.196721 0.016393 0.000000 0.000000 0.000000 0.000000 0.000000 0.016393 0.016393 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.016393 0.000000 0.000000 0.934426 0.016393 0.000000 0.000000 0.000000 0.032787 0.000000 0.000000 0.016393 0.000000 0.000000 0.000000 0.114754 0.000000 0.049180 0.000000 0.000000 0.032787 0.016393 0.000000 0.049180 0.016393 0.672131 0.000000 0.000000 0.000000 0.032787 0.049180 0.000000 0.065574 0.000000 0.131148 0.000000 0.016393 0.000000 0.000000 0.196721 0.000000 0.000000 0.000000 0.114754 0.016393 0.000000 0.000000 0.377049 0.032787 0.016393 0.098361 0.196721 0.000000 0.245902 0.032787 0.016393 0.032787 0.000000 0.000000 0.065574 0.049180 0.000000 0.032787 0.049180 0.016393 0.049180 0.000000 0.065574 0.016393 0.000000 0.147541 0.655738 0.000000 0.114754 0.000000 0.016393 0.016393 0.000000 0.016393 0.000000 0.000000 0.016393 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.557377 0.000000 0.049180 0.000000 0.016393 0.098361 0.000000 0.000000 0.000000 0.000000 0.000000 0.016393 0.016393 0.000000 0.000000 0.114754 0.065574 0.065574 0.000000 0.000000 0.000000 0.000000 0.000000 0.098361 0.000000 0.000000 0.000000 0.000000 0.770492 0.000000 0.016393 0.049180 0.000000 0.000000 0.049180 0.016393 0.000000 0.000000 0.000000 0.000000 0.000000 0.016393 0.000000 0.000000 0.213115 0.000000 0.049180 0.016393 0.000000 0.327869 0.032787 0.049180 0.049180 0.000000 0.000000 0.032787 0.065574 0.114754 0.000000 0.032787 0.000000 0.000000 0.081967 0.524590 0.000000 0.098361 0.000000 0.000000 0.016393 0.016393 0.000000 0.049180 0.000000 0.081967 0.016393 0.016393 0.000000 0.065574 0.000000 0.032787 0.262295 0.000000 0.000000 0.016393 0.016393 0.000000 0.000000 0.032787 0.000000 0.180328 0.032787 0.000000 0.213115 0.000000 0.016393 0.000000 0.229508 0.000000 0.000000 0.000000 0.032787 0.000000 0.229508 0.409836 0.000000 0.065574 0.016393 0.000000 0.032787 0.016393 0.000000 0.065574 0.016393 0.000000 0.000000 0.049180 0.000000 0.049180 0.000000 0.016393 0.000000 0.131148 0.065574 0.000000 0.065574 0.016393 0.032787 0.065574 0.016393 0.016393 0.016393 0.049180 0.000000 0.049180 0.000000 0.131148 0.032787 0.081967 0.000000 0.229508 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SAMSVYGEAKLEAEY MEME-8 regular expression -------------------------------------------------------------------------------- [ST]AMSVYGEAK[LF]E[ATP][ED]Y -------------------------------------------------------------------------------- Time 305.71 secs. ******************************************************************************** ******************************************************************************** MOTIF ATTESLGNDGIFMNKNSGTDMVSIPEELDSCENTQSLLGGCIEVDSKNGI MEME-9 width = 50 sites = 7 llr = 880 E-value = 2.1e-159 ******************************************************************************** -------------------------------------------------------------------------------- Motif ATTESLGNDGIFMNKNSGTDMVSIPEELDSCENTQSLLGGCIEVDSKNGI MEME-9 Description -------------------------------------------------------------------------------- Simplified A 9::::::::::::::::::::::1:::::::::::::::::::::::::: pos.-specific C :::::::3:1::::::3:::::::::::::a:::::::1:a::::::::: probability D ::::::::73:::::::3:a::::::::9::1::::::::::::a::::: matrix E :::a:::::::::::::::::::::99:1::9::::::::::a::::::: F :::::::::::a:::::::::::::::::::::::::4:::::::::::: G ::::::a113:::::::6::::::::1:::::::::::9a::::::::a: H :::::::::::::::::::::::::::::::::::::::::::::::::: I :::::::::1a:1::::::::::7::::::::::1::1:::a::::4::a K ::::::::::::::9::::::::::1::::::1:::::::::::::6::: L :::::a:::::::::::::::::::::a::::::1:a4:::::::::::: M ::::::::::::6:::::3:a:::::::::::::1::::::::::::::: N :::::::31::::a:7:1::::4:::::::::9::::::::::::::a:: P ::::::::::::::::::::::::6:::::::::1::::::::::::::: Q ::::::::::::::::::::::::::::::::::4::::::::::::::: R :4::::::::::::1::::::::1:::::::::::::::::::::::::: S 1:::a::::1::::::6:::::6::::::a:::::a:::::::::a:::: T :6a::::::::::::3::6::::::::::::::a:::::::::::::::: V ::::::::::::3:::::1::a::3::::::::::::::::::a:::::: W :::::::::::::::::::::::::::::::::::::::::::::::::: Y :::::::3::::::::1:::::::1::::::::::::::::::::::::: bits 6.8 6.1 5.4 * * * 4.8 * ** ** * * ** * * Relative 4.1 * * ** * ** * * **** * *** Entropy 3.4 **** ** ****** **** ** ** * ** * ******* **** (181.3 bits) 2.7 ********* **************************************** 2.0 ************************************************** 1.4 ************************************************** 0.7 ************************************************** 0.0 -------------------------------------------------- Multilevel ATTESLGCDDIFMNKNSGTDMVSIPEELDSCENTQSLFGGCIEVDSKNGI consensus R N G V TCDM N V L I sequence Y -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATTESLGNDGIFMNKNSGTDMVSIPEELDSCENTQSLLGGCIEVDSKNGI MEME-9 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------------------------------------------------- RLN19347.1 78 1.98e-58 NRLSRQEDDS ATTESLGNDIIFMNKNSGTDMVSIPEELDSCENTPSLFGGCIEVDSKNGI QGQSMRKMYE XP_021307618.1 107 2.29e-58 KRLSCHDDES ATTESLGYDCIFMNKTSGTDMVSIPEELDSCENTMSLFGGCIEVDSKNGI QEQSLRKMFE NP_001354359.1 80 8.10e-57 KRLYCQDDES ATTESLGYDGIFMNKTSGTDMVSIPEELDSCENTISLFCGCIEVDSKNGI QEQSLRKMFE OEL29447.1 174 4.01e-56 NRLSRQEDDS ATTESLGNDGIFMNKNSGTDMVSIPEELDSCEKTLSLLGGCIEVDSKNGI RGQSMRKMFE XP_014752653.1 67 3.34e-55 NRLTCQEDES ARTESLGCGDIFINKNCDMDMVNIVEELDSCENTQSLLGGCIEVDSINGI ESQSMRKMFK VAI07274.1 79 1.75e-50 DRPTSQEDET ARTESLGGDDIFVNKNCNVDMVNAYKGLDSCENTQSLLGGCIEVDSINGI ESQSMRKRAS EEC74952.1 81 7.73e-47 NRLAWQEDES SRTESLGCNSIFVNRNYDMDMVNRVEELESCDNTQSLIGGCIEVDSINGI ESHKMLKVQA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATTESLGNDGIFMNKNSGTDMVSIPEELDSCENTQSLLGGCIEVDSKNGI MEME-9 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- RLN19347.1 2e-58 77_[9]_136 XP_021307618.1 2.3e-58 106_[9]_137 NP_001354359.1 8.1e-57 79_[9]_137 OEL29447.1 4e-56 173_[9]_136 XP_014752653.1 3.3e-55 66_[9]_130 VAI07274.1 1.7e-50 78_[9]_121 EEC74952.1 7.7e-47 80_[9]_135 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATTESLGNDGIFMNKNSGTDMVSIPEELDSCENTQSLLGGCIEVDSKNGI MEME-9 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF ATTESLGNDGIFMNKNSGTDMVSIPEELDSCENTQSLLGGCIEVDSKNGI width=50 seqs=7 RLN19347.1 ( 78) ATTESLGNDIIFMNKNSGTDMVSIPEELDSCENTPSLFGGCIEVDSKNGI 1 XP_021307618.1 ( 107) ATTESLGYDCIFMNKTSGTDMVSIPEELDSCENTMSLFGGCIEVDSKNGI 1 NP_001354359.1 ( 80) ATTESLGYDGIFMNKTSGTDMVSIPEELDSCENTISLFCGCIEVDSKNGI 1 OEL29447.1 ( 174) ATTESLGNDGIFMNKNSGTDMVSIPEELDSCEKTLSLLGGCIEVDSKNGI 1 XP_014752653.1 ( 67) ARTESLGCGDIFINKNCDMDMVNIVEELDSCENTQSLLGGCIEVDSINGI 1 VAI07274.1 ( 79) ARTESLGGDDIFVNKNCNVDMVNAYKGLDSCENTQSLLGGCIEVDSINGI 1 EEC74952.1 ( 81) SRTESLGCNSIFVNRNYDMDMVNRVEELESCDNTQSLIGGCIEVDSINGI 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATTESLGNDGIFMNKNSGTDMVSIPEELDSCENTQSLLGGCIEVDSKNGI MEME-9 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 20 w= 50 n= 22873 bayes= 11.5174 E= 2.1e-159 401 -101 -406 -393 -305 -126 -336 -229 -329 -270 -233 -336 -340 -316 -262 -45 -144 -74 -268 -354 -148 -287 -358 -335 -377 -283 -233 -262 -74 -323 -275 -230 -331 -169 319 -223 345 -216 -300 -335 -205 -293 -449 -510 -408 -358 -377 -275 -371 -398 -311 -291 -382 -347 -313 -200 427 -231 -351 -428 -420 -568 -260 328 -591 -482 -458 -476 -537 -587 -561 -444 -586 -364 -485 -618 -492 -486 -502 -573 -141 -264 -428 -505 -410 -293 -380 -390 -378 -427 -388 -285 -347 -386 -310 274 -6 -346 -357 -396 -286 -330 -551 -509 -168 -445 -381 -67 -417 350 -59 -475 -388 -344 -318 -508 -307 -120 -255 -316 -161 -366 -336 -426 -454 408 -348 -416 -341 -479 -416 -281 -376 -383 -276 -360 -338 -356 -323 -415 -92 325 -154 -252 -136 111 -133 -204 -185 -252 -239 205 -268 -179 -173 -220 -142 -170 -177 277 -238 -373 343 -164 -402 -79 -233 -354 -329 -409 -391 -2 -388 -297 -293 -352 -292 -322 -329 -351 -29 203 137 -196 -233 219 -147 128 -121 -186 -162 -112 -225 -118 -106 -19 -91 -94 -214 -218 -251 -316 -496 -517 -263 -430 -443 432 -410 -70 -126 -433 -439 -420 -378 -479 -261 101 -324 -332 -283 -266 -495 -514 447 -424 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-350 -393 -304 -442 -177 428 -349 -402 -119 -290 -131 -270 -401 -152 -181 -396 -220 -423 -401 266 -290 -216 -221 186 -107 -323 -362 -325 22 -249 -411 -394 -210 -327 -313 397 -244 -35 -77 -328 -350 -280 39 -357 -176 128 -241 -255 -81 -267 -348 -340 -200 -271 -243 -149 -248 -207 -220 -310 392 -231 -208 -288 -174 176 -215 115 -294 -560 -193 318 -567 -411 -380 -436 -97 -500 -472 -368 -442 -234 -327 -497 -378 -403 -483 -516 -372 -556 -241 325 -582 -203 -433 -467 -460 -563 -536 -409 -534 -324 -445 -565 -450 -461 -497 -556 -286 -330 -551 -509 -168 -445 -381 -67 -417 350 -59 -475 -388 -344 -318 -508 -307 -120 -255 -316 -245 -376 351 -103 -401 -323 -256 -344 -359 -402 -383 -102 -409 -313 -308 -396 -324 -313 -323 -358 -141 -264 -428 -505 -410 -293 -380 -390 -378 -427 -388 -285 -347 -386 -310 274 -6 -346 -357 -396 -309 552 -574 -560 -469 -500 -474 -367 -534 -454 -409 -517 -506 -504 -420 -549 -358 -405 -479 -530 -378 -570 -174 325 -588 -462 -438 -467 -464 -565 -537 -421 -538 -320 -453 -580 -458 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-591 -482 -458 -476 -537 -587 -561 -444 -586 -364 -485 -618 -492 -486 -502 -573 -96 -221 -458 -455 -296 -377 -356 32 -391 -192 -223 -426 -350 -393 -304 -442 -177 428 -349 -402 -266 -388 356 -177 -415 -335 -273 -363 -385 -419 -403 -121 -423 -343 -326 -415 -343 -333 -335 -373 -141 -264 -428 -505 -410 -293 -380 -390 -378 -427 -388 -285 -347 -386 -310 274 -6 -346 -357 -396 -189 -311 -397 -312 -305 -325 -213 301 306 -199 -212 -275 -352 -141 7 -371 -211 -72 -278 -293 -302 -343 -267 -466 -374 -313 -117 -286 -317 -399 -362 399 -357 -274 -289 -279 -232 -320 -274 -349 -161 -366 -336 -426 -454 408 -348 -416 -341 -479 -416 -281 -376 -383 -276 -360 -338 -356 -323 -415 -251 -316 -496 -517 -263 -430 -443 432 -410 -70 -126 -433 -439 -420 -378 -479 -261 101 -324 -332 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATTESLGNDGIFMNKNSGTDMVSIPEELDSCENTQSLLGGCIEVDSKNGI MEME-9 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 20 w= 50 nsites= 7 E= 2.1e-159 0.857143 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.142857 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.428571 0.000000 0.571429 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 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0.000000 0.000000 0.000000 0.000000 0.000000 0.142857 0.000000 0.000000 0.000000 0.857143 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.428571 0.571429 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATTESLGNDGIFMNKNSGTDMVSIPEELDSCENTQSLLGGCIEVDSKNGI MEME-9 regular expression -------------------------------------------------------------------------------- A[TR]TESLG[CNY]D[DG]IF[MV]NK[NT][SC][GD][TM]DMV[SN]I[PV]EELDSCENTQSL[FL]GGCIEVDS[KI]NGI -------------------------------------------------------------------------------- Time 333.78 secs. ******************************************************************************** ******************************************************************************** MOTIF MEEDKENPSZINSFH MEME-10 width = 15 sites = 53 llr = 1064 E-value = 2.7e-151 ******************************************************************************** -------------------------------------------------------------------------------- Motif MEEDKENPSZINSFH MEME-10 Description -------------------------------------------------------------------------------- Simplified A ::1:::::1:::::1 pos.-specific C :::::::::::::11 probability D 1214:11::::1::1 matrix E 176:22:::5::::: F :::::::::::::5: G :::::1::::1:::: H :::::1:::::1::2 I ::::111:::6::1: K :::1211::::1::: L ::::::::::1::11 M 8:::1:::::1:::: N :::12:5::::5::: P :::::::8::::::: Q ::1::2:::3::::1 R ::::::::::::3:1 S :::1:1216::17:: T :::111111:::::: V :11:::::::1::1: W ::::::::::::::: Y :::1:::::::1::1 bits 6.8 6.1 5.4 4.8 Relative 4.1 Entropy 3.4 * * (29.0 bits) 2.7 * * * * 2.0 ** ** ***** 1.4 ***** ********* 0.7 *************** 0.0 --------------- Multilevel MEEDKXNPSEINSFH consensus N Q R sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MEEDKENPSZINSFH MEME-10 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- --------------- XP_017416333.1 1 1.61e-14 . MEEIKDNPSQVNRFH SLSRFQVNGI XP_004137783.2 92 3.95e-14 DWFSRLLGFR MEEKEQNPAEINSFY VISKLRSNPF XP_022948410.1 1 5.28e-14 . MEEKEHNPTEINSFY EISKKRKLPA XP_022145567.1 1 5.28e-14 . MEETKGNPAEINSFY VISKLRNNPF XP_023913884.1 1 1.23e-13 . MNEYNENPSEINSFQ VNKAFKNNII TKY66008.1 1 2.11e-13 . MEESKDNPSQVNRFQ VDEMHNLNIV XP_015896979.1 1 1.80e-12 . MDDDNKSPSEINSFR VVDVIRTIKK TKY63306.1 6 2.88e-12 MFQIE MEADIQNPSQGYRFC VDGVHETNII XP_006410959.1 4 2.88e-12 MPE VEVDNKKPSEINSFH HMISSKNVLK TKS09656.1 1 3.24e-12 . MDEDSDDPSEINSFQ FKEAPNSKLF XP_018806280.1 1 7.18e-12 . MNEATENPAEIYSFH LKKRLKDNIV XP_007134047.1 1 1.12e-11 . MDADIQNPSQGYRFC VDGVHKVNII KZV44349.1 1 1.25e-11 . MEVGMSNPTEINRVD LLCKKRKIRR XP_027336786.1 1 1.92e-11 . MDADIHNPSQGYRFC VDGVHETNIA XP_010529822.1 4 2.64e-11 MPE REVDNQNPSQIFRCH VNGNVLNMEA XP_027353450.1 1 3.61e-11 . MEEKKGNTSQVNRFE VDGMDNLKII XP_018841755.1 1 4.44e-11 . MREDEENPFEVYSFH DNKGLENNTV RXI02216.1 3 4.44e-11 ME MEGFKENPSEIHSFS HLCSAINVLN XP_028119329.1 1 6.03e-11 . MEEDDRDPSEINSAD VNKVLQSSFV XP_015960799.1 1 7.38e-11 . MEETEESPSQMNRLQ VDGMYGISFA XP_024028595.1 1 7.38e-11 . MEENKHSTSEINSLR VISVKKTIKK XP_013448883.1 3 8.16e-11 ME IEARTKIPSQVNRFH VDEMHDINII XP_019459351.1 3 8.16e-11 ME MEQIEDTPSQLNRFQ TDRMQNINIV AAL35819.1 6 1.63e-10 MPEVE VDNNNEKPSEINSFH HMIISSSKNV PON90845.1 1 1.97e-10 . MEENKESPSEIDSRR VISVLNTLKK XP_020553487.1 1 2.17e-10 . MEENTITPAEMNSIA YLNKKRKLHV XP_010528448.1 4 2.89e-10 MSD CEVDNQNPSQITRCS ISNNVLNMEA XP_011077640.1 54 6.10e-10 PGNHLSLQIT MEESMSSPAEVNSIA YLNKKRKLQA PIN04755.1 1 7.32e-10 . MEEKTIIPAEISSVA YLNKKRKFQA XP_009798034.1 1 7.32e-10 . MEEDMIISAHINSVD MNKVLPTSLA XP_008240727.1 1 7.32e-10 . METYEENPSQIDSSH VMSVLKRIKK XP_010256878.1 1 8.77e-10 . MDEDSQDSYEINSFY VNKVMRQTNG XP_010037822.1 1 9.60e-10 . MEEDKASPSDLSSFQ AIKSRNIVDL RWR86109.1 1 9.60e-10 . MEEDKIDPFEIISTD WNKKRKLQGE XP_017215985.1 1 1.26e-09 . MEEDCSDPSDIKSVD GDNVLHASII PSS34997.1 1 1.26e-09 . MEEENNYASQINSID VNEVLQSSIV TEY25303.1 1 1.64e-09 . MEANMITPEEIHSID YLNKKRKLQD XP_010543288.1 2 2.32e-09 M DEDDKTNPSQIHRDI SNPVVDAGSS GAY47919.1 33 2.76e-09 RFQHLPLFLK MEVDNVDRSELNSFL INEIRRADVI XP_012074964.1 2 3.88e-09 M DGGDNENLSEINSFH ITKALNANMF XP_010558336.1 1 4.59e-09 . MDEDETNPSPIDSDV ISHPVADVGS KFK36656.1 5 4.99e-09 MPEE EVDNKKNQSEIYSFH HMISTKNVLN XP_004514391.1 3 5.90e-09 ME IQQTNQIPSQLNRFK VDEMHDINII GAV76568.1 1 6.41e-09 . MEAAHGYTSENNSFH VRKAPNTNIV XP_002531564.2 2 8.21e-09 M DEQDNRNPYATNSFH INKALNGSMF XP_022747248.1 2 9.67e-09 M EVENETNPSQIKSLL NIDHLSKKRK PKI39361.1 1 1.34e-08 . MDEDASSPPEMSSFQ AIKALYGNIS XP_028783417.1 1 1.70e-08 . MEEENANSSHPNRCY LDRFQQTNIV PIN03316.1 1 5.85e-08 . MEKFRSSPTEINGIG YLNKKRKLRN XP_010937591.1 22 6.30e-08 FDRLLLGGAM MDEGIGKPPLIPSIH STEELSPSRV XP_022846646.1 1 1.32e-07 . MEEDVSSPIGITRMK QTSFIDLSKK XP_021289458.1 2 2.69e-07 M EVDSQTNPSQIKSLL NGSMNIVDFN XP_004302767.1 4 3.55e-07 MEM EAEYKQSPTEIVSYP VIEVGKTIKK -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MEEDKENPSZINSFH MEME-10 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- XP_017416333.1 1.6e-14 [10]_217 XP_004137783.2 3.9e-14 91_[10]_241 XP_022948410.1 5.3e-14 [10]_214 XP_022145567.1 5.3e-14 [10]_233 XP_023913884.1 1.2e-13 [10]_230 TKY66008.1 2.1e-13 [10]_211 XP_015896979.1 1.8e-12 [10]_231 TKY63306.1 2.9e-12 5_[10]_242 XP_006410959.1 2.9e-12 3_[10]_173 TKS09656.1 3.2e-12 [10]_246 XP_018806280.1 7.2e-12 [10]_230 XP_007134047.1 1.1e-11 [10]_236 KZV44349.1 1.2e-11 [10]_172 XP_027336786.1 1.9e-11 [10]_238 XP_010529822.1 2.6e-11 3_[10]_181 XP_027353450.1 3.6e-11 [10]_220 XP_018841755.1 4.4e-11 [10]_207 RXI02216.1 4.4e-11 2_[10]_240 XP_028119329.1 6e-11 [10]_226 XP_015960799.1 7.4e-11 [10]_174 XP_024028595.1 7.4e-11 [10]_221 XP_013448883.1 8.2e-11 2_[10]_196 XP_019459351.1 8.2e-11 2_[10]_221 AAL35819.1 1.6e-10 5_[10]_182 PON90845.1 2e-10 [10]_230 XP_020553487.1 2.2e-10 [10]_229 XP_010528448.1 2.9e-10 3_[10]_162 XP_011077640.1 6.1e-10 53_[10]_217 PIN04755.1 7.3e-10 [10]_212 XP_009798034.1 7.3e-10 [10]_244 XP_008240727.1 7.3e-10 [10]_216 XP_010256878.1 8.8e-10 [10]_246 XP_010037822.1 9.6e-10 [10]_242 RWR86109.1 9.6e-10 [10]_238 XP_017215985.1 1.3e-09 [10]_238 PSS34997.1 1.3e-09 [10]_246 TEY25303.1 1.6e-09 [10]_228 XP_010543288.1 2.3e-09 1_[10]_184 GAY47919.1 2.8e-09 32_[10]_237 XP_012074964.1 3.9e-09 1_[10]_241 XP_010558336.1 4.6e-09 [10]_222 KFK36656.1 5e-09 4_[10]_178 XP_004514391.1 5.9e-09 2_[10]_221 GAV76568.1 6.4e-09 [10]_249 XP_002531564.2 8.2e-09 1_[10]_245 XP_022747248.1 9.7e-09 1_[10]_233 PKI39361.1 1.3e-08 [10]_248 XP_028783417.1 1.7e-08 [10]_192 PIN03316.1 5.8e-08 [10]_195 XP_010937591.1 6.3e-08 21_[10]_244 XP_022846646.1 1.3e-07 [10]_230 XP_021289458.1 2.7e-07 1_[10]_237 XP_004302767.1 3.6e-07 3_[10]_238 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MEEDKENPSZINSFH MEME-10 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF MEEDKENPSZINSFH width=15 seqs=53 XP_017416333.1 ( 1) MEEIKDNPSQVNRFH 1 XP_004137783.2 ( 92) MEEKEQNPAEINSFY 1 XP_022948410.1 ( 1) MEEKEHNPTEINSFY 1 XP_022145567.1 ( 1) MEETKGNPAEINSFY 1 XP_023913884.1 ( 1) MNEYNENPSEINSFQ 1 TKY66008.1 ( 1) MEESKDNPSQVNRFQ 1 XP_015896979.1 ( 1) MDDDNKSPSEINSFR 1 TKY63306.1 ( 6) MEADIQNPSQGYRFC 1 XP_006410959.1 ( 4) VEVDNKKPSEINSFH 1 TKS09656.1 ( 1) MDEDSDDPSEINSFQ 1 XP_018806280.1 ( 1) MNEATENPAEIYSFH 1 XP_007134047.1 ( 1) MDADIQNPSQGYRFC 1 KZV44349.1 ( 1) MEVGMSNPTEINRVD 1 XP_027336786.1 ( 1) MDADIHNPSQGYRFC 1 XP_010529822.1 ( 4) REVDNQNPSQIFRCH 1 XP_027353450.1 ( 1) MEEKKGNTSQVNRFE 1 XP_018841755.1 ( 1) MREDEENPFEVYSFH 1 RXI02216.1 ( 3) MEGFKENPSEIHSFS 1 XP_028119329.1 ( 1) MEEDDRDPSEINSAD 1 XP_015960799.1 ( 1) MEETEESPSQMNRLQ 1 XP_024028595.1 ( 1) MEENKHSTSEINSLR 1 XP_013448883.1 ( 3) IEARTKIPSQVNRFH 1 XP_019459351.1 ( 3) MEQIEDTPSQLNRFQ 1 AAL35819.1 ( 6) VDNNNEKPSEINSFH 1 PON90845.1 ( 1) MEENKESPSEIDSRR 1 XP_020553487.1 ( 1) MEENTITPAEMNSIA 1 XP_010528448.1 ( 4) CEVDNQNPSQITRCS 1 XP_011077640.1 ( 54) MEESMSSPAEVNSIA 1 PIN04755.1 ( 1) MEEKTIIPAEISSVA 1 XP_009798034.1 ( 1) MEEDMIISAHINSVD 1 XP_008240727.1 ( 1) METYEENPSQIDSSH 1 XP_010256878.1 ( 1) MDEDSQDSYEINSFY 1 XP_010037822.1 ( 1) MEEDKASPSDLSSFQ 1 RWR86109.1 ( 1) MEEDKIDPFEIISTD 1 XP_017215985.1 ( 1) MEEDCSDPSDIKSVD 1 PSS34997.1 ( 1) MEEENNYASQINSID 1 TEY25303.1 ( 1) MEANMITPEEIHSID 1 XP_010543288.1 ( 2) DEDDKTNPSQIHRDI 1 GAY47919.1 ( 33) MEVDNVDRSELNSFL 1 XP_012074964.1 ( 2) DGGDNENLSEINSFH 1 XP_010558336.1 ( 1) MDEDETNPSPIDSDV 1 KFK36656.1 ( 5) EVDNKKNQSEIYSFH 1 XP_004514391.1 ( 3) IQQTNQIPSQLNRFK 1 GAV76568.1 ( 1) MEAAHGYTSENNSFH 1 XP_002531564.2 ( 2) DEQDNRNPYATNSFH 1 XP_022747248.1 ( 2) EVENETNPSQIKSLL 1 PKI39361.1 ( 1) MDEDASSPPEMSSFQ 1 XP_028783417.1 ( 1) MEEENANSSHPNRCY 1 PIN03316.1 ( 1) MEKFRSSPTEINGIG 1 XP_010937591.1 ( 22) MDEGIGKPPLIPSIH 1 XP_022846646.1 ( 1) MEEDVSSPIGITRMK 1 XP_021289458.1 ( 2) EVDSQTNPSQIKSLL 1 XP_004302767.1 ( 4) EAEYKQSPTEIVSYP 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MEEDKENPSZINSFH MEME-10 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 20 w= 15 n= 26933 bayes= 9.53723 E= 2.7e-151 -304 -43 -79 -76 -357 -483 -451 -6 -459 -260 475 -504 -494 -445 -112 -522 -331 -12 -338 -380 -114 -826 116 270 -766 -151 -502 -594 -390 -609 -578 -58 -503 -87 -88 -576 -464 33 -706 -665 122 -698 8 247 -657 -56 -441 -539 -136 -554 -518 -146 -473 49 -386 -522 -120 104 -604 -578 -8 -454 229 -108 -19 -52 -257 -16 46 -381 -339 114 -351 -197 -44 -111 33 -316 -379 65 -74 -28 -162 55 -427 -341 -32 77 185 -380 130 188 -350 -62 -43 -156 69 -102 -378 -364 -8 -454 -3 70 -427 38 105 108 46 -380 -338 -117 -350 177 27 -25 69 -102 -379 -364 -424 -612 62 -466 -655 -377 -382 85 -4 -672 -660 304 -523 -418 -438 50 29 -607 -617 15 -97 -471 -489 -488 -498 -430 -426 -430 -399 -208 -466 -477 432 -123 -100 -138 6 -379 -497 -539 83 -268 -441 -295 -82 -359 -384 -162 -357 -416 -362 -260 -77 -384 -292 236 119 -377 -363 -57 -113 -825 -74 239 -760 -151 48 -588 -386 -205 -572 -488 -109 288 -454 -577 -461 -503 -700 -662 -274 -357 -483 -502 -285 -129 -443 406 -392 -2 20 -253 -226 -408 -367 -469 -175 161 -328 -335 -255 -408 -79 -355 -151 -350 69 -136 -38 -398 -358 346 -145 -243 -243 -144 -55 -142 -337 113 -331 -513 -714 -791 -752 -141 -671 -719 -639 -744 -709 -616 -617 -649 309 235 -489 -564 -682 -751 -92 131 -113 -562 363 -448 -413 149 -463 6 -32 -480 -462 -431 -88 -261 -99 92 -309 -71 37 125 71 -169 -426 -134 307 -104 -29 -51 -338 -273 -101 159 74 -156 -237 -102 -378 135 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MEEDKENPSZINSFH MEME-10 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 20 w= 15 nsites= 53 E= 2.7e-151 0.000000 0.018868 0.056604 0.075472 0.000000 0.000000 0.000000 0.037736 0.000000 0.000000 0.754717 0.000000 0.000000 0.000000 0.018868 0.000000 0.000000 0.037736 0.000000 0.000000 0.018868 0.000000 0.169811 0.660377 0.000000 0.018868 0.000000 0.000000 0.000000 0.000000 0.000000 0.037736 0.000000 0.018868 0.018868 0.000000 0.000000 0.056604 0.000000 0.000000 0.113208 0.000000 0.075472 0.566038 0.000000 0.037736 0.000000 0.000000 0.018868 0.000000 0.000000 0.018868 0.000000 0.056604 0.000000 0.000000 0.018868 0.094340 0.000000 0.000000 0.037736 0.000000 0.415094 0.037736 0.037736 0.037736 0.000000 0.037736 0.075472 0.000000 0.000000 0.132075 0.000000 0.000000 0.018868 0.056604 0.056604 0.000000 0.000000 0.056604 0.018868 0.018868 0.018868 0.150943 0.000000 0.000000 0.018868 0.075472 0.226415 0.000000 0.075472 0.226415 0.000000 0.018868 0.018868 0.037736 0.075472 0.018868 0.000000 0.000000 0.037736 0.000000 0.075472 0.169811 0.000000 0.075472 0.056604 0.094340 0.075472 0.000000 0.000000 0.018868 0.000000 0.150943 0.037736 0.113208 0.075472 0.018868 0.000000 0.000000 0.000000 0.000000 0.113208 0.000000 0.000000 0.000000 0.000000 0.075472 0.056604 0.000000 0.000000 0.471698 0.000000 0.000000 0.000000 0.188679 0.056604 0.000000 0.000000 0.037736 0.018868 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.018868 0.000000 0.000000 0.811321 0.018868 0.018868 0.056604 0.056604 0.000000 0.000000 0.000000 0.132075 0.000000 0.000000 0.018868 0.037736 0.000000 0.000000 0.018868 0.000000 0.000000 0.000000 0.000000 0.037736 0.000000 0.000000 0.641509 0.075472 0.000000 0.000000 0.037736 0.018868 0.000000 0.037736 0.528302 0.000000 0.018868 0.037736 0.000000 0.000000 0.018868 0.000000 0.000000 0.018868 0.320755 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.056604 0.000000 0.641509 0.000000 0.075472 0.056604 0.018868 0.018868 0.000000 0.000000 0.000000 0.018868 0.113208 0.000000 0.000000 0.000000 0.000000 0.056604 0.000000 0.018868 0.000000 0.056604 0.018868 0.056604 0.000000 0.000000 0.547170 0.018868 0.000000 0.000000 0.056604 0.037736 0.018868 0.000000 0.113208 0.000000 0.000000 0.000000 0.000000 0.000000 0.018868 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.301887 0.679245 0.000000 0.000000 0.000000 0.000000 0.018868 0.056604 0.037736 0.000000 0.528302 0.000000 0.000000 0.113208 0.000000 0.075472 0.018868 0.000000 0.000000 0.000000 0.018868 0.018868 0.018868 0.075472 0.000000 0.018868 0.056604 0.056604 0.132075 0.018868 0.000000 0.018868 0.245283 0.018868 0.037736 0.056604 0.000000 0.000000 0.018868 0.132075 0.056604 0.037736 0.000000 0.018868 0.000000 0.094340 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MEEDKENPSZINSFH MEME-10 regular expression -------------------------------------------------------------------------------- MEED[KN]XNPS[EQ]IN[SR]FH -------------------------------------------------------------------------------- Time 362.10 secs. ******************************************************************************** ******************************************************************************** MOTIF KTYSYDRPSTSSVNW MEME-11 width = 15 sites = 47 llr = 997 E-value = 1.9e-144 ******************************************************************************** -------------------------------------------------------------------------------- Motif KTYSYDRPSTSSVNW MEME-11 Description -------------------------------------------------------------------------------- Simplified A 11:::::2::::2:: pos.-specific C ::2:1:::::::::2 probability D ::1::7:::::::1: matrix E 1:::::1:::::::: F ::1:::::::::1:1 G :::::11:::::1:: H ::1:::1:::::::: I :1:1::::::::::: K 6:::::::::::::: L ::12:::::::11:1 M ::::::::::::::: N :::::1::::::14: P :::21::7::::::: Q :::1::2:::::::: R 1:::::3:::::::: S :1123:::9297131 T :4:1:::::7::::: V :1:1::::::::3:: W ::1::::::::1::4 Y :12:4::::::1::: bits 6.8 6.1 5.4 4.8 Relative 4.1 Entropy 3.4 * * (30.6 bits) 2.7 * **** * 2.0 * ** ***** * 1.4 *************** 0.7 *************** 0.0 --------------- Multilevel KTXSYDRPSTSSVNW consensus PS A SC sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KTYSYDRPSTSSVNW MEME-11 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- --------------- OUZ99277.1 90 2.92e-14 PADMFEPEFP KTYAYDQPSTSSCSC SDNSLKETLS TKS09656.1 120 4.28e-14 GEAKLEMEVS KIWSSDRPSTSSYNW GNSLKDTQYS PIN03316.1 96 4.28e-14 NESNTYSGYR EICPSDQPSTSSVSW GSSSSGTLPS TKR66562.1 117 1.15e-13 GEAKFEMEVS KIWPPDRPSTSSFSC NSLKDAQHSA XP_026417177.1 112 1.65e-13 KPAKFENVYS KTHIYDQPSTSYGSC GSNSFKSTDE OVA17828.1 128 2.97e-13 QPDKFGTGSP RTHFYDQPSTSSGSC GNNSFKSTMH XP_027336786.1 116 3.34e-13 EEGKLVADSA KTYLYGGPSTSLVSW DGYNVKDNHC XP_024189435.1 122 1.30e-12 YSEAELNAAY AKSIYDRPSTSSVNC DVNIFKDTDS XP_023913884.1 121 1.61e-12 DEARLQPEYA NTHLSDGPSTSSVNC PSNCGKYYSL XP_009798034.1 116 1.80e-12 GEAKINPGCL KSCSSDQASTSSFNW GGNWPKNALY TEY72131.1 128 2.23e-12 SDDETDGGFQ ETCTSDEPTTSSASW AGTSSGDSPY XP_023734875.1 94 2.77e-12 NDSENELPYL KISPYDHHSSSSVNW SGRVFDTSVN XP_028773013.1 145 3.81e-12 EEVRLEADSA KTFLYGRPSNSFVNW NGYNVKDVTS XP_021744044.1 86 4.70e-12 TEVIIDAGIQ KTDSYDEASTSWVNS RPITSENDSI RVW33794.1 125 5.22e-12 GEAKFEPECE KTCPYNYPYSSSVNW GGNSSRDDLY XP_015896979.1 115 5.79e-12 VEAKVEPEYV KTYLYDMPSTSSGTE SCKDANYPLD TKY63306.1 121 1.07e-11 EEGKLVADSA KTYQYGRPSASLVGW DGYNVKDNHY XP_004302767.1 120 1.31e-11 YREVEPNPAY AKSVCDRPSTSSVNC NVNIFKDTDS XP_022846646.1 102 1.45e-11 GEAKSDLGSP KTFSSDQASTSSVSS DSFKNSLYSL RXI02216.1 131 2.39e-11 GDSKVGPVYA QTCQYDRPSTSSGKG ISHSADELKY PHT70537.1 130 2.90e-11 HEAKIHPGYL KSYSSDQASTSSVNL GGDWSRNVLY XP_006349495.1 118 3.20e-11 HEAKLDPGCL KACSSDHPSTSSINL GGNWSKNALY XP_021741222.1 84 3.53e-11 TEVVFEAGFR KTESYDEASTSWANS RPVTSGIDSL XP_022742854.1 115 4.28e-11 AEVKFGTDDA KYLPYDRASSSSSDW GSSSQDSHYS PSS34997.1 119 6.90e-11 SEDKIQSEDP RTRPFDRPSTSYLNM GSSSFKNGLY XP_010678090.1 103 1.10e-10 TEVIFDASFR KVDMYDEASTSWANS GSVASQNDSL XP_010937591.1 146 2.74e-10 IDAESGKSFG KVVIQDWPSTSSNSF NSNILKSSID XP_008240727.1 116 2.74e-10 VEAKLEPVYA RACLNDRPSTSYANE VHQPAYPDGE XP_010256878.1 115 3.00e-10 SPYTDTEFEI QAYTYDHHSTSSDSC SSKFIKNALP XP_021856950.1 88 3.28e-10 EVIFDAGNFR KMDSYDEASTSWASS RPVISLDSLS XP_024982170.1 113 5.57e-10 IDSKNELHYL KICPPDQNSDASVNW GSRFFDSSVN PIA54706.1 139 8.58e-10 QPANSKWEFP EVYAGDKPSTSSGSC GSNSSNNTLY XP_012074964.1 117 1.21e-09 YDSKLETEIS KEWPCNGPSSSSFKW GCHNLEDPQC XP_027149457.1 90 1.43e-09 AEVGAGHGYF KEYSSDMPVNSSVDW GGDCSKHALN GAV76568.1 120 1.55e-09 GENKLEIEDT KPSSCDRPSSSSFTC GGSSVKDTCY XP_021289458.1 115 1.69e-09 YEAKFGTEDT KYLLYGRASSSSSDW GSNSQGSLYS XP_008803152.1 200 1.99e-09 VDAESGKPSG KIFLQDWASTSANSF DSNILKSSFD XP_020553487.1 101 2.17e-09 DDAKTYLSYS ETRVSVQPCTSSARW GGTSFQSGLY XP_012832023.1 74 3.26e-09 FYKAYPSYTN TTPVSIEPSTSCVSW DGTSSAEISV XP_020108001.1 120 3.54e-09 FKGSTEKLSG RLVFPDRPSTSSNSS SDNASGSSIT XP_019162543.1 101 9.93e-09 AKVDDLEFLK ACPSSNCPSTSSANL GSSWSKDALY GAY47919.1 147 1.16e-08 GKSRFQAEIG ESLPDDCPSYSSLNW ASSSFKSHSY XP_021650240.1 109 2.48e-08 GEVKFETEVS KLGPSNGPSSSLLNW GQSNCKDVQC PIN04755.1 101 5.56e-08 EDATTYHYFP ETHTSVEPSASSAGF GGTSSEIGLH XP_022747248.1 111 1.60e-07 AEAKFRTEDA NYLQYDRSSSFSSDW GSSFQVSHYS XP_004137783.2 211 5.02e-07 HGAKFELNQA ITCTHDTSTTRSMSF GGASSESIHF PKI43461.1 110 1.48e-06 EGSVSSTMSV SAKLLSTPSTSTAIW SSENQTYSSD -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KTYSYDRPSTSSVNW MEME-11 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- OUZ99277.1 2.9e-14 89_[11]_125 TKS09656.1 4.3e-14 119_[11]_127 PIN03316.1 4.3e-14 95_[11]_100 TKR66562.1 1.1e-13 116_[11]_126 XP_026417177.1 1.6e-13 111_[11]_117 OVA17828.1 3e-13 127_[11]_126 XP_027336786.1 3.3e-13 115_[11]_123 XP_024189435.1 1.3e-12 121_[11]_122 XP_023913884.1 1.6e-12 120_[11]_110 XP_009798034.1 1.8e-12 115_[11]_129 TEY72131.1 2.2e-12 127_[11]_107 XP_023734875.1 2.8e-12 93_[11]_102 XP_028773013.1 3.8e-12 144_[11]_122 XP_021744044.1 4.7e-12 85_[11]_106 RVW33794.1 5.2e-12 124_[11]_121 XP_015896979.1 5.8e-12 114_[11]_117 TKY63306.1 1.1e-11 120_[11]_127 XP_004302767.1 1.3e-11 119_[11]_122 XP_022846646.1 1.5e-11 101_[11]_129 RXI02216.1 2.4e-11 130_[11]_112 PHT70537.1 2.9e-11 129_[11]_128 XP_006349495.1 3.2e-11 117_[11]_128 XP_021741222.1 3.5e-11 83_[11]_107 XP_022742854.1 4.3e-11 114_[11]_124 PSS34997.1 6.9e-11 118_[11]_128 XP_010678090.1 1.1e-10 102_[11]_111 XP_010937591.1 2.7e-10 145_[11]_120 XP_008240727.1 2.7e-10 115_[11]_101 XP_010256878.1 3e-10 114_[11]_132 XP_021856950.1 3.3e-10 87_[11]_102 XP_024982170.1 5.6e-10 112_[11]_112 PIA54706.1 8.6e-10 138_[11]_110 XP_012074964.1 1.2e-09 116_[11]_126 XP_027149457.1 1.4e-09 89_[11]_128 GAV76568.1 1.6e-09 119_[11]_130 XP_021289458.1 1.7e-09 114_[11]_124 XP_008803152.1 2e-09 199_[11]_125 XP_020553487.1 2.2e-09 100_[11]_129 XP_012832023.1 3.3e-09 73_[11]_106 XP_020108001.1 3.5e-09 119_[11]_112 XP_019162543.1 9.9e-09 100_[11]_129 GAY47919.1 1.2e-08 146_[11]_123 XP_021650240.1 2.5e-08 108_[11]_126 PIN04755.1 5.6e-08 100_[11]_112 XP_022747248.1 1.6e-07 110_[11]_124 XP_004137783.2 5e-07 210_[11]_122 PKI43461.1 1.5e-06 109_[11]_117 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KTYSYDRPSTSSVNW MEME-11 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF KTYSYDRPSTSSVNW width=15 seqs=47 OUZ99277.1 ( 90) KTYAYDQPSTSSCSC 1 TKS09656.1 ( 120) KIWSSDRPSTSSYNW 1 PIN03316.1 ( 96) EICPSDQPSTSSVSW 1 TKR66562.1 ( 117) KIWPPDRPSTSSFSC 1 XP_026417177.1 ( 112) KTHIYDQPSTSYGSC 1 OVA17828.1 ( 128) RTHFYDQPSTSSGSC 1 XP_027336786.1 ( 116) KTYLYGGPSTSLVSW 1 XP_024189435.1 ( 122) AKSIYDRPSTSSVNC 1 XP_023913884.1 ( 121) NTHLSDGPSTSSVNC 1 XP_009798034.1 ( 116) KSCSSDQASTSSFNW 1 TEY72131.1 ( 128) ETCTSDEPTTSSASW 1 XP_023734875.1 ( 94) KISPYDHHSSSSVNW 1 XP_028773013.1 ( 145) KTFLYGRPSNSFVNW 1 XP_021744044.1 ( 86) KTDSYDEASTSWVNS 1 RVW33794.1 ( 125) KTCPYNYPYSSSVNW 1 XP_015896979.1 ( 115) KTYLYDMPSTSSGTE 1 TKY63306.1 ( 121) KTYQYGRPSASLVGW 1 XP_004302767.1 ( 120) AKSVCDRPSTSSVNC 1 XP_022846646.1 ( 102) KTFSSDQASTSSVSS 1 RXI02216.1 ( 131) QTCQYDRPSTSSGKG 1 PHT70537.1 ( 130) KSYSSDQASTSSVNL 1 XP_006349495.1 ( 118) KACSSDHPSTSSINL 1 XP_021741222.1 ( 84) KTESYDEASTSWANS 1 XP_022742854.1 ( 115) KYLPYDRASSSSSDW 1 PSS34997.1 ( 119) RTRPFDRPSTSYLNM 1 XP_010678090.1 ( 103) KVDMYDEASTSWANS 1 XP_010937591.1 ( 146) KVVIQDWPSTSSNSF 1 XP_008240727.1 ( 116) RACLNDRPSTSYANE 1 XP_010256878.1 ( 115) QAYTYDHHSTSSDSC 1 XP_021856950.1 ( 88) KMDSYDEASTSWASS 1 XP_024982170.1 ( 113) KICPPDQNSDASVNW 1 PIA54706.1 ( 139) EVYAGDKPSTSSGSC 1 XP_012074964.1 ( 117) KEWPCNGPSSSSFKW 1 XP_027149457.1 ( 90) KEYSSDMPVNSSVDW 1 GAV76568.1 ( 120) KPSSCDRPSSSSFTC 1 XP_021289458.1 ( 115) KYLLYGRASSSSSDW 1 XP_008803152.1 ( 200) KIFLQDWASTSANSF 1 XP_020553487.1 ( 101) ETRVSVQPCTSSARW 1 XP_012832023.1 ( 74) TTPVSIEPSTSCVSW 1 XP_020108001.1 ( 120) RLVFPDRPSTSSNSS 1 XP_019162543.1 ( 101) ACPSSNCPSTSSANL 1 GAY47919.1 ( 147) ESLPDDCPSYSSLNW 1 XP_021650240.1 ( 109) KLGPSNGPSSSLLNW 1 PIN04755.1 ( 101) ETHTSVEPSASSAGF 1 XP_022747248.1 ( 111) NYLQYDRSSSFSSDW 1 XP_004137783.2 ( 211) ITCTHDTSTTRSMSF 1 PKI43461.1 ( 110) SAKLLSTPSTSTAIW 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KTYSYDRPSTSSVNW MEME-11 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 20 w= 15 n= 26933 bayes= 10.2434 E= 1.9e-144 49 -469 -346 32 -449 -360 -268 -90 315 -394 -354 -32 -370 19 130 -218 -80 -332 -391 -382 85 2 -572 -130 -292 -428 -389 167 -51 -55 -15 -447 -95 -397 -362 -106 300 76 -307 86 -182 262 -65 -214 120 -152 145 -245 -138 -18 -255 -323 -32 -281 1 -95 -262 -21 237 301 1 -315 -596 -545 13 -431 -395 83 -444 111 -13 -462 226 52 -373 71 85 78 -304 -332 -187 112 -190 -358 63 -150 12 -252 -284 -155 -261 -144 22 -27 -237 69 -266 -231 -113 367 -308 -435 343 -221 -461 -48 -313 -186 -423 -466 -447 -6 -471 -383 -369 -317 -380 -107 -384 -418 -192 84 -314 52 -418 53 120 -357 -73 -369 51 -263 -341 208 293 -337 -1 -305 205 -65 189 -456 -478 -482 -494 -414 41 -427 -395 -435 -461 -157 412 -378 -360 -172 -336 -373 -492 -533 -176 -50 -444 -515 -405 -354 -388 -376 -361 -421 -366 -264 -359 -387 -295 262 91 -155 -365 -127 -28 -371 -201 -577 -489 -492 -448 -338 -430 -479 -363 -53 -474 -404 -379 25 392 -296 -437 -92 -69 -381 -626 -685 -100 -397 -560 -547 -561 -588 -537 -465 -492 -546 -78 278 -181 -451 -529 -557 -89 -35 -474 -530 -120 -380 -385 -301 -383 -73 -328 -297 -383 -399 -317 239 43 -295 262 42 194 3 -189 -545 104 85 -395 -27 -444 -9 -13 9 -448 -412 -373 -107 -262 281 -304 -57 -382 -582 24 -431 -614 -28 -356 -96 -40 -616 -594 281 -491 -376 -64 132 -9 -552 -573 -517 -243 321 -601 -130 105 -131 -400 -163 -452 -11 -15 -470 -458 -420 -382 -13 -273 -149 542 -322 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KTYSYDRPSTSSVNW MEME-11 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 20 w= 15 nsites= 47 E= 1.9e-144 0.063830 0.000000 0.000000 0.127660 0.000000 0.000000 0.000000 0.021277 0.574468 0.000000 0.000000 0.042553 0.000000 0.042553 0.085106 0.021277 0.021277 0.000000 0.000000 0.000000 0.085106 0.021277 0.000000 0.042553 0.000000 0.000000 0.000000 0.127660 0.042553 0.042553 0.021277 0.000000 0.021277 0.000000 0.000000 0.063830 0.404255 0.063830 0.000000 0.063830 0.000000 0.191489 0.063830 0.021277 0.063830 0.021277 0.085106 0.000000 0.021277 0.085106 0.000000 0.000000 0.042553 0.000000 0.042553 0.085106 0.000000 0.042553 0.063830 0.170213 0.042553 0.000000 0.000000 0.000000 0.042553 0.000000 0.000000 0.063830 0.000000 0.170213 0.021277 0.000000 0.212766 0.063830 0.000000 0.234043 0.085106 0.063830 0.000000 0.000000 0.000000 0.063830 0.021277 0.000000 0.021277 0.021277 0.021277 0.000000 0.000000 0.021277 0.000000 0.021277 0.063830 0.042553 0.000000 0.297872 0.000000 0.000000 0.000000 0.404255 0.000000 0.000000 0.744681 0.000000 0.000000 0.085106 0.000000 0.021277 0.000000 0.000000 0.000000 0.085106 0.000000 0.000000 0.000000 0.021277 0.000000 0.042553 0.000000 0.000000 0.000000 0.042553 0.000000 0.148936 0.000000 0.085106 0.063830 0.000000 0.021277 0.000000 0.042553 0.000000 0.000000 0.191489 0.297872 0.000000 0.042553 0.000000 0.042553 0.021277 0.212766 0.000000 0.000000 0.000000 0.000000 0.000000 0.042553 0.000000 0.000000 0.000000 0.000000 0.021277 0.680851 0.000000 0.000000 0.042553 0.000000 0.000000 0.000000 0.000000 0.000000 0.021277 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.893617 0.042553 0.021277 0.000000 0.021277 0.042553 0.000000 0.021277 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.042553 0.000000 0.000000 0.000000 0.170213 0.702128 0.000000 0.000000 0.021277 0.021277 0.000000 0.000000 0.000000 0.021277 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.021277 0.936170 0.000000 0.000000 0.000000 0.000000 0.021277 0.021277 0.000000 0.000000 0.021277 0.000000 0.000000 0.000000 0.000000 0.063830 0.000000 0.000000 0.000000 0.000000 0.000000 0.702128 0.021277 0.000000 0.085106 0.063830 0.191489 0.021277 0.021277 0.000000 0.085106 0.106383 0.000000 0.021277 0.000000 0.063830 0.021277 0.063830 0.000000 0.000000 0.000000 0.063830 0.000000 0.319149 0.000000 0.021277 0.000000 0.000000 0.085106 0.000000 0.000000 0.042553 0.000000 0.021277 0.042553 0.000000 0.000000 0.404255 0.000000 0.000000 0.021277 0.340426 0.042553 0.000000 0.000000 0.000000 0.000000 0.212766 0.000000 0.042553 0.085106 0.021277 0.000000 0.000000 0.000000 0.063830 0.021277 0.000000 0.000000 0.000000 0.000000 0.127660 0.000000 0.000000 0.425532 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KTYSYDRPSTSSVNW MEME-11 regular expression -------------------------------------------------------------------------------- KTX[SP][YS]DR[PA]STSSV[NS][WC] -------------------------------------------------------------------------------- Time 390.78 secs. ******************************************************************************** ******************************************************************************** MOTIF TSASSSSSNNFSSEAFSSSHSSGTRETDSWVMHDLEHDHSGLMLQPHDDD MEME-12 width = 50 sites = 7 llr = 811 E-value = 5.1e-119 ******************************************************************************** -------------------------------------------------------------------------------- Motif TSASSSSSNNFSSEAFSSSHSSGTRETDSWVMHDLEHDHSGLMLQPHDDD MEME-12 Description -------------------------------------------------------------------------------- Simplified A 4:9:::::::::::9:::::::::::::::1::::::::::::::1:::: pos.-specific C :::::::::::::::::1:::::::::::::::::::::::::::::::: probability D :::::::::::::4:::::::::::4:a::1:16:::6::1::::::7a7 matrix E :::::::::::::6:::::::::::6:::::::::a:::::::::::::: F :1::::::::6::::9::3::::::::::::::::::::::::::::::: G :::::::::::::::::::1::a::::::::::::::11:6::::::::: H :::::::::::::::::::7::::::::::::44::637:::::::6::: I :::::::::14:::::::::::::::::::::::3::::::::::::::: K ::::::::::::::::::::::::4:::::::::::::::::::3::::: L ::::::::::::::::::::::::::::::::::4::::::61a1::::3 M :::::::::::::::::::::::::::::::7::::::::::9::::::: N ::::::::a9::::::1::::1::::::::::::::1::::::::::3:: P ::::::::::::::::::::::::::::::::3::::::3:::::9:::: Q ::::::::::::::::::::::::::::::::1:::::::::::6::::: R :::::::::::::::::::11:::6::::::3::::1:1::::::::::: S :91aaaaa:::aa:::797:97::::::a::::::::::71::::::::: T 6:::::::::::::1:1::::::a::a::::::::::::::1:::::::: V ::::::::::::::::::::::::::::::7:::3::::::3:::::::: W :::::::::::::::::::::::::::::a:::::::::::::::::::: Y :::::::::::::::1:::::1::::::::::::::1:::1:::::4::: bits 6.8 * 6.1 * 5.4 * 4.8 * * * Relative 4.1 * ** * ** * * * * * ** Entropy 3.4 * * *** ** * *** ** *** * ** * ** ** * (167.2 bits) 2.7 **************** **** **************************** 2.0 ************************************************** 1.4 ************************************************** 0.7 ************************************************** 0.0 -------------------------------------------------- Multilevel TSASSSSSNNFSSEAFSSSHSSGTRETDSWVMHDLEHDHSGLMLQPHDDD consensus A I D F KD RPHI H P V K YN L sequence V -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TSASSSSSNNFSSEAFSSSHSSGTRETDSWVMHDLEHDHSGLMLQPHDDD MEME-12 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------------------------------------------------- OEL29447.1 236 6.39e-57 QSMRKMFEIR TSASSSSSNNFSSEAFSSSHSSGTRETDSWVMHDVEHDHSGLMLQPHDDL ERMYSVLEQY RLN19347.1 140 5.64e-51 QSMRKMYEIR TSASSSSSNIFSSEAFSCSHSSGTRETDSWVMHDVEHGHSSLMLQPHDDL ERIYNVLEQY XP_021307618.1 169 1.29e-50 QSLRKMFEIG TSASSSSSNNFSSEAFNSSHSSGTRETDSWVMHDIENHHSDVMLKPHNDD LERIYNVLEQ XP_014752653.1 129 2.56e-49 QSMRKMFKVR ASASSSSSNNISSDAFSSFGRSGTKDTDSWVRPHLEHDRSGTMLQPYDDD IERIYDVMNE NP_001354359.1 142 4.02e-49 QSLRKMFEIR TSASSSSSNNFSSEAFSSSHSSGTRDTDSWAMDDIERHHPYVMLKPHNDD LERIFNVLEQ VAI07274.1 137 1.39e-45 GIESQSMRKR ASASSSSSNNISSDTYSSFHSYGTKETDSWVRPHLEHDGSGLLLQAYDDD IEKICAVMNE EEC74952.1 140 5.64e-45 IESHKMLKVQ AFSSSSSSNNISSDAFTSSRSNGTKDTDSWDMQHLEYDHPGLMLLPYDDD IEEAYDVLGQ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TSASSSSSNNFSSEAFSSSHSSGTRETDSWVMHDLEHDHSGLMLQPHDDD MEME-12 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- OEL29447.1 6.4e-57 235_[12]_74 RLN19347.1 5.6e-51 139_[12]_74 XP_021307618.1 1.3e-50 168_[12]_75 XP_014752653.1 2.6e-49 128_[12]_68 NP_001354359.1 4e-49 141_[12]_75 VAI07274.1 1.4e-45 136_[12]_63 EEC74952.1 5.6e-45 139_[12]_76 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TSASSSSSNNFSSEAFSSSHSSGTRETDSWVMHDLEHDHSGLMLQPHDDD MEME-12 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TSASSSSSNNFSSEAFSSSHSSGTRETDSWVMHDLEHDHSGLMLQPHDDD width=50 seqs=7 OEL29447.1 ( 236) TSASSSSSNNFSSEAFSSSHSSGTRETDSWVMHDVEHDHSGLMLQPHDDL 1 RLN19347.1 ( 140) TSASSSSSNIFSSEAFSCSHSSGTRETDSWVMHDVEHGHSSLMLQPHDDL 1 XP_021307618.1 ( 169) TSASSSSSNNFSSEAFNSSHSSGTRETDSWVMHDIENHHSDVMLKPHNDD 1 XP_014752653.1 ( 129) ASASSSSSNNISSDAFSSFGRSGTKDTDSWVRPHLEHDRSGTMLQPYDDD 1 NP_001354359.1 ( 142) TSASSSSSNNFSSEAFSSSHSSGTRDTDSWAMDDIERHHPYVMLKPHNDD 1 VAI07274.1 ( 137) ASASSSSSNNISSDTYSSFHSYGTKETDSWVRPHLEHDGSGLLLQAYDDD 1 EEC74952.1 ( 140) AFSSSSSSNNISSDAFTSSRSNGTKDTDSWDMQHLEYDHPGLMLLPYDDD 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TSASSSSSNNFSSEAFSSSHSSGTRETDSWVMHDLEHDHSGLMLQPHDDD MEME-12 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 20 w= 50 n= 22873 bayes= 11.5174 E= 5.1e-119 300 -177 -444 -463 -392 -174 -375 -287 -384 -368 -316 -314 -297 -333 -310 -187 344 -184 -352 -420 -93 -201 -370 -438 61 -261 -290 -286 -299 -324 -290 -207 -293 -313 -235 248 85 -270 -235 -203 401 -101 -406 -393 -305 -126 -336 -229 -329 -270 -233 -336 -340 -316 -262 -45 -144 -74 -268 -354 -141 -264 -428 -505 -410 -293 -380 -390 -378 -427 -388 -285 -347 -386 -310 274 -6 -346 -357 -396 -141 -264 -428 -505 -410 -293 -380 -390 -378 -427 -388 -285 -347 -386 -310 274 -6 -346 -357 -396 -141 -264 -428 -505 -410 -293 -380 -390 -378 -427 -388 -285 -347 -386 -310 274 -6 -346 -357 -396 -141 -264 -428 -505 -410 -293 -380 -390 -378 -427 -388 -285 -347 -386 -310 274 -6 -346 -357 -396 -141 -264 -428 -505 -410 -293 -380 -390 -378 -427 -388 -285 -347 -386 -310 274 -6 -346 -357 -396 -302 -343 -267 -466 -374 -313 -117 -286 -317 -399 -362 399 -357 -274 -289 -279 -232 -320 -274 -349 -283 -321 -251 -454 -349 -304 -92 -103 -296 -366 -330 394 -342 -252 -269 -257 -209 -279 -252 -328 -259 -291 -591 -577 363 -466 -333 310 -483 -44 -99 -481 -447 -416 -401 -515 -291 -26 -162 -108 -141 -264 -428 -505 -410 -293 -380 -390 -378 -427 -388 -285 -347 -386 -310 274 -6 -346 -357 -396 -141 -264 -428 -505 -410 -293 -380 -390 -378 -427 -388 -285 -347 -386 -310 274 -6 -346 -357 -396 -137 -566 213 242 -526 -283 -265 -365 -164 -382 -353 -225 -275 -79 -232 -341 -234 -281 -465 -428 401 -109 -413 -401 -314 -131 -342 -234 -337 -279 -243 -339 -333 -320 -269 -166 77 -85 -278 -361 -275 -255 -488 -503 439 -422 -307 -188 -435 -142 -217 -431 -372 -423 -377 -421 -363 -208 -85 84 -91 -182 -329 -407 -317 -260 -287 -287 -263 -331 -277 -45 -269 -287 -202 241 161 -288 -277 -305 -52 159 -385 -452 -346 -225 -328 -311 -313 -357 -306 -217 -282 -321 -244 249 80 -263 -306 -341 -105 -241 -403 -464 239 -260 -268 -280 -354 -306 -304 -273 -334 -338 -289 228 -43 -245 -171 -98 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228 -48 -273 -356 -393 -128 -338 -41 -323 -407 376 -254 -371 -257 -427 -370 -159 -326 -279 -220 -116 -255 -315 -300 41 -156 -220 -500 -451 -147 -363 -325 34 -356 280 -51 -390 -350 -311 -279 -399 99 229 -216 -255 -370 -368 -576 -602 -337 -487 -470 -183 -486 -100 504 -518 -473 -472 -466 -555 -388 -239 -255 -330 -286 -330 -551 -509 -168 -445 -381 -67 -417 350 -59 -475 -388 -344 -318 -508 -307 -120 -255 -316 -155 -334 -313 -196 -369 -286 -90 -260 184 14 -210 -205 -282 361 45 -310 -182 -227 -244 -291 76 -301 -333 -332 -341 -262 -270 -274 -244 -283 -309 -318 430 -227 -209 -275 -184 -219 -338 -381 -337 -341 -426 -478 -6 -403 432 -316 -399 -284 -301 -256 -399 -206 -236 -430 -328 -300 -27 342 -240 -375 342 -164 -403 -276 -234 -356 -328 -411 -393 57 -388 -296 -294 -352 -292 -324 -330 -351 -266 -388 356 -177 -415 -335 -273 -363 -385 -419 -403 -121 -423 -343 -326 -415 -343 -333 -335 -373 -252 -385 335 -184 -369 -321 -276 -295 -342 58 -344 -142 -403 -309 -308 -399 -317 -283 -330 -350 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TSASSSSSNNFSSEAFSSSHSSGTRETDSWVMHDLEHDHSGLMLQPHDDD MEME-12 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 20 w= 50 nsites= 7 E= 5.1e-119 0.428571 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.571429 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.142857 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.857143 0.000000 0.000000 0.000000 0.000000 0.857143 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.142857 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 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0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.714286 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.285714 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TSASSSSSNNFSSEAFSSSHSSGTRETDSWVMHDLEHDHSGLMLQPHDDD MEME-12 regular expression -------------------------------------------------------------------------------- [TA]SASSSSSNN[FI]SS[ED]AFSS[SF]HSSGT[RK][ED]TDSWV[MR][HP][DH][LIV]EH[DH]H[SP]G[LV]ML[QK]P[HY][DN]D[DL] -------------------------------------------------------------------------------- Time 415.06 secs. ******************************************************************************** ******************************************************************************** MOTIF VNRGSYSEEETFVDSECNPSYDDADIQAL MEME-13 width = 29 sites = 10 llr = 599 E-value = 2.2e-078 ******************************************************************************** -------------------------------------------------------------------------------- Motif VNRGSYSEEETFVDSECNPSYDDADIQAL MEME-13 Description -------------------------------------------------------------------------------- Simplified A ::::::::313::::::::::::6:1:8: pos.-specific C ::::31::::::::::6:::::::::::: probability D 12::::::23::1a:::::::55:a::1: matrix E :2:::::956:::::7:1::::2:::::: F :::::::::::7::::::::::::::::: G :::3::3:::::::::::::::::::::: H :::::::::::::::::::1:5::::::: I 1::11:1:::112::::2:::::::4::: K :14::::1::::::33::::::::::::: L :::2:::::::1::::::1::::1:22:9 M :::1::::::::::::::::::::::::1 N :5::1::::::::::::7::::::::::: P ::::::::::::::::::81:::2::::: Q ::::::::::::::::::1:::::::8:: R ::5:1:::::::::2:::::::::::::: S ::1:436::::1::4::::8::::::::: T :::1:1::::6:1:1::::::::1:3:1: V 8::2::::::::6:::::::::::::::: W ::::::::::::::::::::::::::::: Y :::::5::::::::::4:::a:3:::::: bits 6.8 6.1 5.4 4.8 * Relative 4.1 * * Entropy 3.4 * * * * * ** * *** (86.4 bits) 2.7 * * * * **** ************** 2.0 ***************************** 1.4 ***************************** 0.7 ***************************** 0.0 ----------------------------- Multilevel VNRGSYSEEETFVDSECNPSYDDADIQAL consensus DKLCSG ADA I KKYI HYP TL sequence E V D R E L -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VNRGSYSEEETFVDSECNPSYDDADIQAL MEME-13 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- ----------------------------- XP_027353450.1 125 1.35e-30 EADCGNAYLY VNRISYSEEEAFVDSKCNPSYDDPDIQAL KNHEELLGLG XP_027336786.1 147 4.34e-29 DNHCSLDVSA DEKGCSGEADTFVDKECNPSYHYADIQAL KNLEEQILEL XP_004514391.1 127 9.77e-29 DADCANAYLC VNRLSYSEEETFIDRKYNPSYDDLDTQAL ENPEERLLRL TKY63306.1 152 3.37e-28 DNHYSLDESV VDKGCSGEAETSVDKECNPSYHYADLQAL KNLEQQILEI PNX96427.1 110 2.34e-27 EADSANTSLC VNRLNYSEDETFIDSKYNPSYDDPDTQAM EIPEQHLLIN XP_007134047.1 147 7.29e-27 DNHHTLDDSA VDKGCTGEADTFDDKECNPSYHYADLLAL KNLEEKIIEI XP_017416333.1 121 3.29e-25 ETDCENSYLY VNRMSYIEEEAFVDTECIPHYDDTDAQDL NNDEEHLMGI TKY66008.1 115 4.36e-25 EPDCGNSYLY VNRVSYSKEEALVDSEYIPPYDDADIQAL ENHEEHLLGL XP_028773013.1 170 7.20e-24 NGYNVKDVTS IEKTISSEEDIFTDREYNQSYHEADIQAL QNLEEQIVGC XP_019459351.1 127 4.51e-20 EEEGTNTYLY VKSVRCSEDATIVDSECELSYHEADTLTL ENYEEHLLGL -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VNRGSYSEEETFVDSECNPSYDDADIQAL MEME-13 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- XP_027353450.1 1.3e-30 124_[13]_82 XP_027336786.1 4.3e-29 146_[13]_78 XP_004514391.1 9.8e-29 126_[13]_83 TKY63306.1 3.4e-28 151_[13]_82 PNX96427.1 2.3e-27 109_[13]_77 XP_007134047.1 7.3e-27 146_[13]_76 XP_017416333.1 3.3e-25 120_[13]_83 TKY66008.1 4.4e-25 114_[13]_83 XP_028773013.1 7.2e-24 169_[13]_83 XP_019459351.1 4.5e-20 126_[13]_83 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VNRGSYSEEETFVDSECNPSYDDADIQAL MEME-13 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF VNRGSYSEEETFVDSECNPSYDDADIQAL width=29 seqs=10 XP_027353450.1 ( 125) VNRISYSEEEAFVDSKCNPSYDDPDIQAL 1 XP_027336786.1 ( 147) DEKGCSGEADTFVDKECNPSYHYADIQAL 1 XP_004514391.1 ( 127) VNRLSYSEEETFIDRKYNPSYDDLDTQAL 1 TKY63306.1 ( 152) VDKGCSGEAETSVDKECNPSYHYADLQAL 1 PNX96427.1 ( 110) VNRLNYSEDETFIDSKYNPSYDDPDTQAM 1 XP_007134047.1 ( 147) VDKGCTGEADTFDDKECNPSYHYADLLAL 1 XP_017416333.1 ( 121) VNRMSYIEEEAFVDTECIPHYDDTDAQDL 1 TKY66008.1 ( 115) VNRVSYSKEEALVDSEYIPPYDDADIQAL 1 XP_028773013.1 ( 170) IEKTISSEEDIFTDREYNQSYHEADIQAL 1 XP_019459351.1 ( 127) VKSVRCSEDATIVDSECELSYHEADTLTL 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VNRGSYSEEETFVDSECNPSYDDADIQAL MEME-13 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 20 w= 29 n= 25309 bayes= 11.5565 E= 2.2e-078 -38 -178 -163 -393 -270 -348 -295 99 -334 -178 -199 -376 -298 -338 -243 -401 -123 412 -311 -388 -185 -432 131 101 -458 -197 -193 -411 64 -425 -402 289 -302 -157 -215 -266 -205 -347 -413 -358 -235 -406 -425 -311 -478 -335 -183 -333 266 -327 -304 -260 -363 -102 365 -65 -240 -296 -308 -345 -71 -148 -431 -380 -121 192 -232 150 -280 125 162 -298 -284 -247 -209 -298 94 212 -140 -168 -66 312 -252 -241 -232 -216 -180 94 -125 -181 -158 46 -252 -142 113 142 -27 -95 -218 -230 -58 182 -380 -394 -32 -225 -144 -205 -315 -247 -236 -295 -302 -295 -253 83 89 -161 -137 372 -40 -218 -412 -472 -413 226 -379 110 -396 -389 -358 -306 -329 -360 -334 205 -135 -230 -383 -424 -355 -574 -229 323 -589 -453 -426 -463 -187 -549 -522 -412 -509 -295 -408 -559 -437 -449 -502 -555 231 -604 129 228 -559 -317 -297 -390 -187 -406 -375 -273 -299 -102 -255 -370 -259 -304 -500 -460 88 -624 176 250 -569 -323 -303 -393 -190 -410 -379 -280 -302 -103 -261 -377 -264 -307 -509 -468 225 -221 -451 -474 -332 -276 -359 102 -353 -276 -237 -288 -343 -321 -294 -185 362 -103 -321 -379 -261 -245 -483 -496 438 -418 -384 -68 -434 -79 -202 -442 -365 -436 -385 -270 -354 -191 -118 -56 -36 -176 -164 -390 -262 -343 -290 132 -329 -173 -191 -370 -295 -331 -238 -394 -23 403 -300 -373 -290 -409 359 -201 -436 -357 -296 -386 -409 -441 -426 -144 -443 -367 -349 -438 -366 -356 -355 -395 -163 -365 -310 -245 -399 -279 -161 -294 225 -297 -267 -205 -305 -87 243 124 91 -251 -286 -302 -177 -558 -122 264 -544 -327 -280 -386 207 -397 -368 -279 -315 -110 -152 -380 -264 -310 -451 -438 -364 471 -614 -666 -112 -458 -274 -391 -547 -385 -423 -489 -504 -472 -438 -538 -441 -377 -130 357 -248 -336 -212 -131 -360 -268 -116 69 -253 -362 -333 378 -334 -229 -239 -262 -207 -270 -277 -329 -91 -327 -346 -343 -353 -286 -282 -285 -254 -62 -321 -333 427 22 -219 -295 -202 -235 -353 -393 -101 -210 -313 -398 -342 -253 66 -318 -274 -360 -310 -175 10 -293 -222 245 86 -301 -304 -322 -509 -500 -637 -704 -170 -511 -324 -482 -593 -455 -500 -547 -533 -526 -481 -642 -531 -476 -190 486 -337 -487 264 -344 -471 -292 415 -558 -347 -552 -566 -182 -418 -328 -347 -381 -333 -506 -429 -382 -186 -480 257 112 -396 -260 -241 -394 -207 -412 -390 -152 -315 -145 -248 -325 -245 -326 -376 268 363 -153 -417 -394 -304 -174 -329 -200 -319 -10 -233 -338 178 -302 -264 -208 70 -105 -285 -342 -290 -409 359 -201 -436 -357 -296 -386 -409 -441 -426 -144 -443 -367 -349 -438 -366 -356 -355 -395 96 -195 -480 -436 -167 -322 -297 309 -337 126 -89 -354 -340 -306 -270 -351 232 36 -202 -230 -210 -333 -419 -211 -355 -396 -51 -271 -270 -6 -179 -285 -308 425 -160 -396 -275 -276 -246 -367 397 -114 -77 -359 -310 -140 -325 -233 -315 -273 -238 -308 -362 -307 -260 -171 21 -80 -274 -354 -272 -316 -550 -490 -146 -459 -370 -46 -401 339 123 -464 -378 -323 -300 -495 -289 -102 -241 -308 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VNRGSYSEEETFVDSECNPSYDDADIQAL MEME-13 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 20 w= 29 nsites= 10 E= 2.2e-078 0.000000 0.000000 0.100000 0.000000 0.000000 0.000000 0.000000 0.100000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.800000 0.000000 0.000000 0.000000 0.000000 0.200000 0.200000 0.000000 0.000000 0.000000 0.000000 0.100000 0.000000 0.000000 0.500000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.400000 0.000000 0.000000 0.000000 0.000000 0.000000 0.500000 0.100000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.300000 0.000000 0.100000 0.000000 0.200000 0.100000 0.000000 0.000000 0.000000 0.000000 0.000000 0.100000 0.200000 0.000000 0.000000 0.000000 0.300000 0.000000 0.000000 0.000000 0.000000 0.000000 0.100000 0.000000 0.000000 0.000000 0.100000 0.000000 0.000000 0.100000 0.400000 0.000000 0.000000 0.000000 0.000000 0.000000 0.100000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.300000 0.100000 0.000000 0.000000 0.500000 0.000000 0.000000 0.000000 0.000000 0.000000 0.300000 0.000000 0.100000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.600000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.900000 0.000000 0.000000 0.000000 0.000000 0.100000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.300000 0.000000 0.200000 0.500000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.100000 0.000000 0.300000 0.600000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.300000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.100000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.600000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.700000 0.000000 0.000000 0.100000 0.000000 0.100000 0.000000 0.000000 0.000000 0.000000 0.000000 0.100000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.100000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.100000 0.600000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.300000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.400000 0.100000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.700000 0.000000 0.000000 0.000000 0.000000 0.300000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.600000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.400000 0.000000 0.000000 0.000000 0.100000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.700000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.100000 0.000000 0.000000 0.800000 0.100000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.100000 0.000000 0.000000 0.000000 0.000000 0.000000 0.100000 0.000000 0.000000 0.800000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.500000 0.000000 0.000000 0.000000 0.500000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.500000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.300000 0.600000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.100000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.100000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.100000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.400000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.300000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.800000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.800000 0.000000 0.100000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.100000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.900000 0.100000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VNRGSYSEEETFVDSECNPSYDDADIQAL MEME-13 regular expression -------------------------------------------------------------------------------- V[NDE][RK][GLV][SC][YS][SG]E[EAD][ED][TA]F[VI]D[SKR][EK][CY][NI]PSY[DH][DYE][AP]D[ITL][QL]AL -------------------------------------------------------------------------------- Time 440.35 secs. ******************************************************************************** ******************************************************************************** MOTIF SASMFDENPELESMNTQIIKG MEME-14 width = 21 sites = 32 llr = 836 E-value = 6.7e-076 ******************************************************************************** -------------------------------------------------------------------------------- Motif SASMFDENPELESMNTQIIKG MEME-14 Description -------------------------------------------------------------------------------- Simplified A :3:::::::12::1:2::::: pos.-specific C ::::1:::::::::::1:::: probability D 1::::4:::1:13:1:::::: matrix E :1:::37::5:8:::::1::3 F ::2:3::::::::11::1::: G ::::::2:::::::::::::4 H 2:::::::::::1:2:2:::: I :::3:::::11::121:33:: K ::::::1::::1:::::::6: L 12113::11:3::3::1:1:: M :::3:::::::::4:::1::: N :::::2:7::::1:222::2: P 2::1::::5:::::::::::: Q ::::::::2:::::2:3:::: R ::::::::11::::::::::1 S 216:2::11:::3::1::1:2 T 1111::::::2::::2:21:: V :3:1:::::12::::1:23:: W ::::::::::::::::::::: Y ::::1:::::::::::1:::: bits 6.8 6.1 5.4 4.8 Relative 4.1 Entropy 3.4 (37.7 bits) 2.7 * 2.0 ****** * ** *** 1.4 ********************* 0.7 ********************* 0.0 --------------------- Multilevel SASMFDENPELESMNTQIIKG consensus V ILE DL VNE sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SASMFDENPELESMNTQIIKG MEME-14 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- --------------------- XP_008240727.1 52 9.88e-18 CWERIFPSDE PVSMFDENPEVKNMQTCATKG KVEGVILDGG XP_027353450.1 56 3.05e-17 KCWLGSFSSE HASMFNENPALDNMHNYMIKS RMDAAFIDDG XP_007134047.1 56 7.83e-17 KCWVGNSSSE HASSFDENPALESMQIYVLKG RRDAESSEAN TKY63306.1 61 2.84e-16 RCWVGNSSSE HALIFDKNPALESMQIYVLKG RADADSSESE XP_021622766.1 33 1.19e-14 KCWDNHSSPK TLSILEENQEAEDLITEVVKE SAGRQAIEDG XP_018841755.1 56 1.64e-14 KCWDRSFASE PVFVFEKNPEVESIFPNIING KTERAAMDYE XP_022983598.1 55 4.25e-14 KHCNEGFPSK LAFLYNGLPETEHMNVQFIKG SANVLRFDDG XP_019459351.1 58 8.69e-14 KCRVGHLSSE HTSMFDEKRHLESMNNHTVKS MTDTTAINVR XP_027336786.1 56 9.62e-14 KCWLGNSSSE HASMFEENRALESMQIYVLED RTGADSSEPE XP_015960799.1 56 2.13e-13 KCWVGSFCSK HASTSDENQVLESVHNQMVKI QTDAAFLDER XP_021650240.1 43 2.58e-13 KCWDNHSSPK TLPMLEENQEAEDLIANEVKE SDARHAMEDV RXI02216.1 67 3.13e-13 CWARVFPSDE SVSMFDGNLEIKNMQKQTLNS KIDGASLDDR TKS09656.1 56 6.10e-13 KCWDHRLPLK NSTICEENQEDKDLITHIIKE NAERRAIDEG XP_004137783.2 147 6.10e-13 KHCSEEFASK SAFLYGGLPETEHMNVQFIKE NANVLCFDEV XP_021691173.1 63 8.87e-13 NCWDHDSSPK PLLILEENQEAEDLIAKEVKE SAERQSIEDG XP_022145567.1 56 1.07e-12 KHCSEGFPSK SAFPYSGEPETEHMNVQFIKG NSNVMCFGKG XP_002531564.2 57 1.28e-12 KCWDHRIIYR PPSILEENQEADDLIAHVTQE NAERQAIEDV GAV76568.1 56 1.54e-12 KFSNRSLLSE LTSIFEGNPVTEGIHSVIQKG ELEGGFIDDV GAY47919.1 88 1.54e-12 KCSDGSFRSK SLSTLDEVSEVENLQTNIIKG GATIDGFEQE RVW33794.1 61 7.56e-12 KCCGRSFSSQ IVYPLDEDTEIEDLHAQIVKE ETNGETIDDG XP_018806280.1 56 8.98e-12 KFCARSFACE PVSVFETNPGVESIFTNIKTE KAEGAAMDDE PNX96427.1 41 9.77e-12 KCRVESSSSE DESMIDESPILESANNHTVNR RTDAAFLDDR XP_023913884.1 56 1.76e-11 GCWDHSFASE DVTVFEKIPKAEIFCTNIING KTGGATMVNN XP_015896979.1 51 2.67e-11 KCWQSSPSNE SVSMSIENPDVQSLHSSIIGG KTEEHVLEDR XP_028773013.1 81 4.01e-11 KCWVRSFPSE EASILDENLRSERMHDLPVNG KPGALVHDDR XP_022948410.1 46 8.90e-11 KHSNEASPSK SVFLHDGLPETELMTVQFSKG NPNVICIDEG XP_010037822.1 54 1.42e-10 KCLDGGFDPV LLSEYDANPDIEDLPAFRIKR PTEGGCNHDE PSS34997.1 56 1.93e-10 KCWERSFSSE YDSPSNENLNIEDFDLQITKG KSVGGANDYE XP_013448883.1 58 2.08e-10 KCRVESFSSE DTSMSDESPIFGSANNHTVNS RMDVAFLDDR XP_004514391.1 58 2.43e-10 KCRVENVSSE GASMLNESSILESADNHTVNS RVDASSAEDR XP_028119329.1 54 6.87e-10 KHKCWDRTSS SESQSNENLRVEDFNILLSKG KTVVGARDSE TKR66562.1 53 7.94e-10 KCWDHRFPLK TSKICEENEEEKDLITCIIAE NAERQAIDEG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SASMFDENPELESMNTQIIKG MEME-14 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- XP_008240727.1 9.9e-18 51_[14]_159 XP_027353450.1 3e-17 55_[14]_159 XP_007134047.1 7.8e-17 55_[14]_175 TKY63306.1 2.8e-16 60_[14]_181 XP_021622766.1 1.2e-14 32_[14]_184 XP_018841755.1 1.6e-14 55_[14]_146 XP_022983598.1 4.2e-14 54_[14]_178 XP_019459351.1 8.7e-14 57_[14]_160 XP_027336786.1 9.6e-14 55_[14]_177 XP_015960799.1 2.1e-13 55_[14]_113 XP_021650240.1 2.6e-13 42_[14]_186 RXI02216.1 3.1e-13 66_[14]_170 TKS09656.1 6.1e-13 55_[14]_185 XP_004137783.2 6.1e-13 146_[14]_180 XP_021691173.1 8.9e-13 62_[14]_169 XP_022145567.1 1.1e-12 55_[14]_172 XP_002531564.2 1.3e-12 56_[14]_184 GAV76568.1 1.5e-12 55_[14]_188 GAY47919.1 1.5e-12 87_[14]_176 RVW33794.1 7.6e-12 60_[14]_179 XP_018806280.1 9e-12 55_[14]_169 PNX96427.1 9.8e-12 40_[14]_154 XP_023913884.1 1.8e-11 55_[14]_169 XP_015896979.1 2.7e-11 50_[14]_175 XP_028773013.1 4e-11 80_[14]_180 XP_022948410.1 8.9e-11 45_[14]_163 XP_010037822.1 1.4e-10 53_[14]_183 PSS34997.1 1.9e-10 55_[14]_185 XP_013448883.1 2.1e-10 57_[14]_135 XP_004514391.1 2.4e-10 57_[14]_160 XP_028119329.1 6.9e-10 53_[14]_167 TKR66562.1 7.9e-10 52_[14]_184 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SASMFDENPELESMNTQIIKG MEME-14 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF SASMFDENPELESMNTQIIKG width=21 seqs=32 XP_008240727.1 ( 52) PVSMFDENPEVKNMQTCATKG 1 XP_027353450.1 ( 56) HASMFNENPALDNMHNYMIKS 1 XP_007134047.1 ( 56) HASSFDENPALESMQIYVLKG 1 TKY63306.1 ( 61) HALIFDKNPALESMQIYVLKG 1 XP_021622766.1 ( 33) TLSILEENQEAEDLITEVVKE 1 XP_018841755.1 ( 56) PVFVFEKNPEVESIFPNIING 1 XP_022983598.1 ( 55) LAFLYNGLPETEHMNVQFIKG 1 XP_019459351.1 ( 58) HTSMFDEKRHLESMNNHTVKS 1 XP_027336786.1 ( 56) HASMFEENRALESMQIYVLED 1 XP_015960799.1 ( 56) HASTSDENQVLESVHNQMVKI 1 XP_021650240.1 ( 43) TLPMLEENQEAEDLIANEVKE 1 RXI02216.1 ( 67) SVSMFDGNLEIKNMQKQTLNS 1 TKS09656.1 ( 56) NSTICEENQEDKDLITHIIKE 1 XP_004137783.2 ( 147) SAFLYGGLPETEHMNVQFIKE 1 XP_021691173.1 ( 63) PLLILEENQEAEDLIAKEVKE 1 XP_022145567.1 ( 56) SAFPYSGEPETEHMNVQFIKG 1 XP_002531564.2 ( 57) PPSILEENQEADDLIAHVTQE 1 GAV76568.1 ( 56) LTSIFEGNPVTEGIHSVIQKG 1 GAY47919.1 ( 88) SLSTLDEVSEVENLQTNIIKG 1 RVW33794.1 ( 61) IVYPLDEDTEIEDLHAQIVKE 1 XP_018806280.1 ( 56) PVSVFETNPGVESIFTNIKTE 1 PNX96427.1 ( 41) DESMIDESPILESANNHTVNR 1 XP_023913884.1 ( 56) DVTVFEKIPKAEIFCTNIING 1 XP_015896979.1 ( 51) SVSMSIENPDVQSLHSSIIGG 1 XP_028773013.1 ( 81) EASILDENLRSERMHDLPVNG 1 XP_022948410.1 ( 46) SVFLHDGLPETELMTVQFSKG 1 XP_010037822.1 ( 54) LLSEYDANPDIEDLPAFRIKR 1 PSS34997.1 ( 56) YDSPSNENLNIEDFDLQITKG 1 XP_013448883.1 ( 58) DTSMSDESPIFGSANNHTVNS 1 XP_004514391.1 ( 58) GASMLNESSILESADNHTVNS 1 XP_028119329.1 ( 54) SESQSNENLRVEDFNILLSKG 1 TKR66562.1 ( 53) TSKICEENEEEKDLITCIIAE 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SASMFDENPELESMNTQIIKG MEME-14 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 20 w= 21 n= 26237 bayes= 8.04158 E= 6.7e-076 -143 -392 21 -110 -366 -73 260 -43 -136 10 -278 -56 170 -140 -131 55 93 -253 -319 -19 256 -310 -122 -64 -289 -331 -271 -166 -235 90 -213 -300 -44 -229 -216 -104 95 238 -287 -300 -152 -240 -411 -471 90 -329 -346 -307 -152 -117 -313 -235 -114 -346 -260 233 117 -306 -319 -94 -187 -266 -545 -174 -240 -382 -346 253 -394 39 331 -413 104 -47 -323 -194 46 126 -256 -284 -306 147 -628 -596 302 -485 26 -12 -494 161 -280 -491 -496 -448 -412 15 -332 -210 -208 197 -349 -588 236 174 -629 -68 -344 -46 -361 -610 -595 148 -458 -320 -398 -186 -362 -529 -589 -518 -45 -659 -241 267 -681 166 -426 -527 63 -543 -512 -393 -440 -247 -364 -493 -57 -441 -617 -586 -304 -353 -198 -301 -381 -332 -121 -155 -197 -140 -358 385 -367 -272 -288 -161 -235 -173 -282 -358 -182 -419 -416 -183 -442 -371 -351 -373 -303 25 -400 -394 382 171 48 -131 -71 -322 -432 -464 132 -398 -27 200 -371 -73 28 99 -30 -323 -282 -57 -294 -139 87 -290 -181 41 -323 -309 163 -266 -141 -174 -22 -382 -346 165 -393 159 -168 -412 -400 -361 -323 -194 163 209 -256 -284 -299 -785 -8 285 -715 -85 -444 -531 101 -547 -516 -427 -438 -21 -398 -519 -403 -443 -653 -611 -260 -483 195 -324 -486 -65 175 -44 -255 -133 -425 118 -389 -256 -6 127 -274 -393 -443 -409 94 -452 -774 -723 122 -610 -557 129 -626 202 368 -647 -595 -547 -537 -657 -423 -19 -388 -451 -165 38 -28 -259 47 -298 263 201 -176 -299 -269 179 -41 201 -168 -313 -30 -223 -321 -315 161 -325 -117 -285 -300 -317 -244 150 -53 -97 -222 154 -43 -197 -184 -101 207 143 -289 -297 -144 129 -270 -113 -48 -286 262 -282 -32 -40 -268 130 -295 237 -134 -163 -179 -38 -310 166 -25 -266 -548 -82 152 -383 -347 283 -396 -67 116 -414 -46 -364 -21 -414 163 186 -255 -284 -193 -272 -539 -496 -243 -387 -353 307 -102 69 -162 -414 -404 -55 -327 -119 89 270 -261 -288 -44 -498 -303 -139 -509 -71 -282 -445 329 -453 -420 189 -408 -22 -174 -382 -45 -396 -438 -422 -289 -573 -85 149 -580 288 -344 -46 -297 -517 -485 -265 -423 -258 77 16 -338 -434 -530 -493 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SASMFDENPELESMNTQIIKG MEME-14 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 20 w= 21 nsites= 32 E= 6.7e-076 0.000000 0.000000 0.093750 0.031250 0.000000 0.031250 0.187500 0.031250 0.000000 0.093750 0.000000 0.031250 0.156250 0.000000 0.000000 0.218750 0.093750 0.000000 0.000000 0.031250 0.312500 0.000000 0.031250 0.062500 0.000000 0.000000 0.000000 0.000000 0.000000 0.156250 0.000000 0.000000 0.031250 0.000000 0.000000 0.062500 0.093750 0.250000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.156250 0.000000 0.000000 0.000000 0.031250 0.062500 0.000000 0.000000 0.031250 0.000000 0.000000 0.625000 0.062500 0.000000 0.000000 0.031250 0.000000 0.000000 0.000000 0.031250 0.000000 0.000000 0.000000 0.250000 0.000000 0.093750 0.312500 0.000000 0.093750 0.031250 0.000000 0.031250 0.062500 0.093750 0.000000 0.000000 0.000000 0.062500 0.000000 0.000000 0.343750 0.000000 0.031250 0.031250 0.000000 0.250000 0.000000 0.000000 0.000000 0.000000 0.000000 0.156250 0.000000 0.000000 0.000000 0.125000 0.000000 0.000000 0.406250 0.343750 0.000000 0.031250 0.000000 0.031250 0.000000 0.000000 0.000000 0.156250 0.000000 0.000000 0.000000 0.031250 0.000000 0.000000 0.000000 0.000000 0.031250 0.000000 0.000000 0.656250 0.000000 0.187500 0.000000 0.000000 0.093750 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.031250 0.000000 0.000000 0.000000 0.000000 0.000000 0.031250 0.031250 0.000000 0.000000 0.000000 0.031250 0.031250 0.093750 0.000000 0.656250 0.000000 0.000000 0.000000 0.093750 0.000000 0.031250 0.000000 0.000000 0.000000 0.000000 0.000000 0.031250 0.000000 0.000000 0.000000 0.000000 0.000000 0.125000 0.000000 0.000000 0.500000 0.187500 0.062500 0.062500 0.031250 0.000000 0.000000 0.000000 0.125000 0.000000 0.062500 0.468750 0.000000 0.031250 0.031250 0.093750 0.031250 0.000000 0.000000 0.031250 0.000000 0.000000 0.062500 0.000000 0.000000 0.062500 0.000000 0.000000 0.156250 0.000000 0.031250 0.031250 0.031250 0.000000 0.000000 0.125000 0.000000 0.250000 0.000000 0.000000 0.000000 0.000000 0.000000 0.031250 0.156250 0.187500 0.000000 0.000000 0.000000 0.000000 0.062500 0.750000 0.000000 0.031250 0.000000 0.000000 0.125000 0.000000 0.000000 0.000000 0.000000 0.031250 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.312500 0.000000 0.000000 0.031250 0.093750 0.031250 0.000000 0.031250 0.000000 0.125000 0.000000 0.000000 0.031250 0.343750 0.000000 0.000000 0.000000 0.000000 0.093750 0.000000 0.000000 0.000000 0.093750 0.000000 0.000000 0.093750 0.000000 0.312500 0.375000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.031250 0.000000 0.000000 0.000000 0.031250 0.062500 0.000000 0.062500 0.000000 0.187500 0.187500 0.000000 0.000000 0.000000 0.218750 0.031250 0.187500 0.000000 0.000000 0.031250 0.000000 0.000000 0.000000 0.156250 0.000000 0.031250 0.000000 0.000000 0.000000 0.000000 0.125000 0.031250 0.031250 0.000000 0.187500 0.031250 0.000000 0.000000 0.062500 0.218750 0.125000 0.000000 0.000000 0.000000 0.062500 0.000000 0.031250 0.031250 0.000000 0.187500 0.000000 0.031250 0.062500 0.000000 0.156250 0.000000 0.250000 0.000000 0.031250 0.000000 0.031250 0.000000 0.125000 0.031250 0.000000 0.000000 0.062500 0.125000 0.000000 0.000000 0.312500 0.000000 0.031250 0.062500 0.000000 0.031250 0.000000 0.031250 0.000000 0.156250 0.156250 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.343750 0.031250 0.125000 0.000000 0.000000 0.000000 0.031250 0.000000 0.062500 0.093750 0.312500 0.000000 0.000000 0.031250 0.000000 0.000000 0.031250 0.000000 0.031250 0.000000 0.000000 0.625000 0.000000 0.000000 0.218750 0.000000 0.031250 0.000000 0.000000 0.031250 0.000000 0.000000 0.000000 0.000000 0.000000 0.031250 0.281250 0.000000 0.437500 0.000000 0.031250 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.062500 0.156250 0.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SASMFDENPELESMNTQIIKG MEME-14 regular expression -------------------------------------------------------------------------------- S[AV]S[MI][FL][DE]ENPELE[SD][ML]NTQI[IV][KN][GE] -------------------------------------------------------------------------------- Time 465.13 secs. ******************************************************************************** ******************************************************************************** MOTIF SKDALYSLESRSVTKS MEME-15 width = 16 sites = 29 llr = 642 E-value = 1.7e-049 ******************************************************************************** -------------------------------------------------------------------------------- Motif SKDALYSLESRSVTKS MEME-15 Description -------------------------------------------------------------------------------- Simplified A :::2::::::113::1 pos.-specific C 1::::1:::::::::: probability D ::3:::::2::::::: matrix E :2::::::5:::::2: F 2::::1:::::1:::: G :::1::::1::::::: H ::111::::::::::: I ::11::::::::1::: K :5::::::1:::::5: L ::::4::6::::1::1 M ::::::::::::12:: N ::2:11::1::::::: P 1::::::::::::::: Q :1::2::::::::::: R :1::::::::3::::: S 6:221:92:924::26 T :::1::::::23:7:1 V :::1:::1::::31:: W :::::::::::::::: Y :::::6:::::::::: bits 6.8 6.1 5.4 4.8 Relative 4.1 Entropy 3.4 (31.9 bits) 2.7 ** * * 2.0 ** *** ****** 1.4 **************** 0.7 **************** 0.0 ---------------- Multilevel SKDALYSLESRSATKS consensus ESS S STV E sequence T -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SKDALYSLESRSVTKS MEME-15 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- ---------------- XP_019162543.1 120 3.75e-17 TSSANLGSSW SKDALYSLESRSMTKS DSHRTERTHV XP_006349495.1 137 2.08e-15 TSSINLGGNW SKNALYSLESRSVTKL MPDKLEQSPT XP_022846646.1 119 6.45e-15 ASTSSVSSDS FKNSLYSLESRSLTKS CSSKVASSNF XP_028119329.1 117 1.36e-14 SGEAKIQLEF FKNSLYSLESRSFTKS GADRVQQPYI XP_009798034.1 135 1.82e-14 TSSFNWGGNW PKNALYSLESRSVTKL TPDRPEQPPT PHT70537.1 149 1.18e-13 TSSVNLGGDW SRNVLYSLESRSITKL MPDRSEQSPT RAL39303.1 98 1.92e-13 TSEASLDSGW SRDALYSLESRCVTKP DLYAGNECAF XP_012832023.1 94 5.49e-13 SCVSWDGTSS AEISVYSLESRSVTKS STGKSKPLSI PIN04755.1 120 8.57e-13 ASSAGFGGTS SEIGLHSLESRSITKS SSSKSGPFEE XP_020553487.1 120 1.82e-12 TSSARWGGTS FQSGLYSLESRSGTKS SSCKSESLSI XP_011077640.1 174 3.37e-12 SSSVSWADST SEISLYSSKSTSLTKS CCSEPESLSV XP_021622766.1 116 1.09e-11 SSLLDFCQSN SKDIQCSLHSTTATST VGAGKDESAF XP_022145567.1 133 3.61e-11 SQSISCGSAS SESTQFSLESSTAMES SSTEQEAAFV XP_021650240.1 128 6.67e-11 SSLLNWGQSN CKDVQCSLNSATATST GGAGKDEPAF XP_012850185.1 101 1.11e-10 EVYETSTSSY SEIHFYSSKSVSLTKS NPSQTESLSL XP_004137783.2 230 1.43e-10 TRSMSFGGAS SESIHFSVESSTAMES SSTEQETAFP XP_027149457.1 109 1.43e-10 NSSVDWGGDC SKHALNSSESSFITES SSHILESPSI XP_027176296.1 119 3.78e-10 NSSVTCGGNC SKHAQNSSKSSFIMKS SSHILESPSA XP_015896979.1 131 4.79e-10 MPSTSSGTES CKDANYPLDSLTVVKA SSGKEELAFS OAY41326.1 73 6.53e-10 SSLLDFGQSN SKDIQSSLNSTMATST VGAGKDESAF GAV76568.1 139 1.29e-09 SSSFTCGGSS VKDTCYSLDITAAVET GAENEEVRIV XP_021289458.1 133 1.39e-09 SSSSSDWGSN SQGSLYSSDSTAVVSS SVEKEVQSSP XP_022983598.1 136 1.74e-09 TQCMSFGGAS SGSTNFSVESSTAMES SSTEQEVAFA XP_022948410.1 117 2.32e-09 NQALSCTRDS SESTHFCVGSSTAMES SSTEQEVAFA RVW33794.1 144 2.32e-09 SSSVNWGGNS SRDDLYSLKSTRMTPD VRKDKMTFFS OMO66336.1 129 2.70e-08 SSSFSDWASS SRESHYSSDSTTVASE GVEREVLSSP GAY47919.1 166 4.21e-08 YSSLNWASSS FKSHSYSSNSAAKTEG GSGKEQFNFV PSS23773.1 87 1.60e-07 TDTSISSSNR PSHLSVSLDDISVTKS RADKKKAPYI OAO95598.1 100 2.14e-07 ASFTGPSLYM FKDSIYSTGSSSSGYA ATSSIEQCFS -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SKDALYSLESRSVTKS MEME-15 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- XP_019162543.1 3.7e-17 119_[15]_109 XP_006349495.1 2.1e-15 136_[15]_108 XP_022846646.1 6.4e-15 118_[15]_111 XP_028119329.1 1.4e-14 116_[15]_109 XP_009798034.1 1.8e-14 134_[15]_109 PHT70537.1 1.2e-13 148_[15]_108 RAL39303.1 1.9e-13 97_[15]_98 XP_012832023.1 5.5e-13 93_[15]_85 PIN04755.1 8.6e-13 119_[15]_92 XP_020553487.1 1.8e-12 119_[15]_109 XP_011077640.1 3.4e-12 173_[15]_96 XP_021622766.1 1.1e-11 115_[15]_106 XP_022145567.1 3.6e-11 132_[15]_100 XP_021650240.1 6.7e-11 127_[15]_106 XP_012850185.1 1.1e-10 100_[15]_88 XP_004137783.2 1.4e-10 229_[15]_102 XP_027149457.1 1.4e-10 108_[15]_108 XP_027176296.1 3.8e-10 118_[15]_108 XP_015896979.1 4.8e-10 130_[15]_100 OAY41326.1 6.5e-10 72_[15]_107 GAV76568.1 1.3e-09 138_[15]_110 XP_021289458.1 1.4e-09 132_[15]_105 XP_022983598.1 1.7e-09 135_[15]_102 XP_022948410.1 2.3e-09 116_[15]_97 RVW33794.1 2.3e-09 143_[15]_101 OMO66336.1 2.7e-08 128_[15]_105 GAY47919.1 4.2e-08 165_[15]_103 PSS23773.1 1.6e-07 86_[15]_101 OAO95598.1 2.1e-07 99_[15]_86 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SKDALYSLESRSVTKS MEME-15 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF SKDALYSLESRSVTKS width=16 seqs=29 XP_019162543.1 ( 120) SKDALYSLESRSMTKS 1 XP_006349495.1 ( 137) SKNALYSLESRSVTKL 1 XP_022846646.1 ( 119) FKNSLYSLESRSLTKS 1 XP_028119329.1 ( 117) FKNSLYSLESRSFTKS 1 XP_009798034.1 ( 135) PKNALYSLESRSVTKL 1 PHT70537.1 ( 149) SRNVLYSLESRSITKL 1 RAL39303.1 ( 98) SRDALYSLESRCVTKP 1 XP_012832023.1 ( 94) AEISVYSLESRSVTKS 1 PIN04755.1 ( 120) SEIGLHSLESRSITKS 1 XP_020553487.1 ( 120) FQSGLYSLESRSGTKS 1 XP_011077640.1 ( 174) SEISLYSSKSTSLTKS 1 XP_021622766.1 ( 116) SKDIQCSLHSTTATST 1 XP_022145567.1 ( 133) SESTQFSLESSTAMES 1 XP_021650240.1 ( 128) CKDVQCSLNSATATST 1 XP_012850185.1 ( 101) SEIHFYSSKSVSLTKS 1 XP_004137783.2 ( 230) SESIHFSVESSTAMES 1 XP_027149457.1 ( 109) SKHALNSSESSFITES 1 XP_027176296.1 ( 119) SKHAQNSSKSSFIMKS 1 XP_015896979.1 ( 131) CKDANYPLDSLTVVKA 1 OAY41326.1 ( 73) SKDIQSSLNSTMATST 1 GAV76568.1 ( 139) VKDTCYSLDITAAVET 1 XP_021289458.1 ( 133) SQGSLYSSDSTAVVSS 1 XP_022983598.1 ( 136) SGSTNFSVESSTAMES 1 XP_022948410.1 ( 117) SESTHFCVGSSTAMES 1 RVW33794.1 ( 144) SRDDLYSLKSTRMTPD 1 OMO66336.1 ( 129) SRESHYSSDSTTVASE 1 GAY47919.1 ( 166) FKSHSYSSNSAAKTEG 1 PSS23773.1 ( 87) PSHLSVSLDDISVTKS 1 OAO95598.1 ( 100) FKDSIYSTGSSSSGYA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SKDALYSLESRSVTKS MEME-15 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 20 w= 16 n= 26817 bayes= 8.08203 E= 1.7e-049 2 167 -672 -688 203 -337 -569 -457 -615 -516 -483 -528 73 -538 -512 219 -284 -26 -517 -575 -325 -527 -458 117 -570 -70 -301 -444 297 -441 -414 -364 -460 77 204 -188 -341 -401 -429 -454 -347 -534 199 -137 -581 -49 192 166 -349 -603 -593 165 -445 -340 -366 60 -329 -539 -543 -474 221 -274 -119 -360 -251 19 122 135 -271 -67 -177 -325 -355 -260 -239 67 144 85 -258 -278 -178 60 -516 -466 -12 -370 176 30 -368 239 -153 12 -385 181 -303 -102 -204 30 -246 -275 -143 86 -354 -348 189 -317 59 -194 -280 -207 -206 -45 -293 -280 -211 -205 -236 -54 -41 407 -177 62 -599 -656 -551 -350 -534 -515 -543 -556 -505 -440 -32 -515 -459 275 -157 -408 -505 -557 -238 -359 -666 -637 -345 -426 -505 -172 -546 293 -257 -543 -493 -492 -463 75 -38 130 -402 -443 -324 -575 118 220 -607 33 39 -562 116 -575 -555 94 -438 -292 -367 -402 -344 -494 -564 -501 -203 -325 -134 -525 -472 -351 -418 -52 -418 -485 -439 -297 -411 -427 -363 271 -49 -398 -433 -456 59 -277 -477 -437 -264 -365 -329 17 -329 -72 -189 -363 -386 -317 306 69 233 18 -273 -301 34 -20 -406 -475 -35 -322 -348 -326 -321 -375 -70 -225 -322 -346 -81 218 211 -327 -325 -356 238 -254 -537 -486 -10 -71 -335 177 -83 51 128 -403 -388 -352 -313 -183 -202 258 -243 -272 -19 -329 -568 -602 -461 -71 -473 -311 -475 -425 241 -394 -449 -435 -409 -284 379 112 -434 -501 -263 -513 -295 123 -516 -369 -294 -430 301 -437 -405 -287 -29 -212 -152 28 -299 -376 -435 -5 -7 -231 -202 -248 -364 -146 -338 -333 -308 -74 -323 -220 -115 -333 -248 229 158 -337 -324 -352 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SKDALYSLESRSVTKS MEME-15 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 20 w= 16 nsites= 29 E= 1.7e-049 0.034483 0.068966 0.000000 0.000000 0.172414 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.068966 0.000000 0.000000 0.620690 0.000000 0.034483 0.000000 0.000000 0.000000 0.000000 0.000000 0.241379 0.000000 0.034483 0.000000 0.000000 0.482759 0.000000 0.000000 0.000000 0.000000 0.068966 0.137931 0.034483 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.310345 0.034483 0.000000 0.034483 0.103448 0.137931 0.000000 0.000000 0.000000 0.172414 0.000000 0.000000 0.000000 0.206897 0.000000 0.000000 0.000000 0.000000 0.241379 0.000000 0.034483 0.000000 0.000000 0.068966 0.068966 0.103448 0.000000 0.034483 0.000000 0.000000 0.000000 0.000000 0.000000 0.241379 0.137931 0.068966 0.000000 0.000000 0.000000 0.034483 0.000000 0.000000 0.034483 0.000000 0.103448 0.034483 0.000000 0.448276 0.000000 0.068966 0.000000 0.172414 0.000000 0.068966 0.000000 0.034483 0.000000 0.000000 0.000000 0.068966 0.000000 0.000000 0.137931 0.000000 0.034483 0.000000 0.000000 0.000000 0.000000 0.068966 0.000000 0.000000 0.000000 0.034483 0.000000 0.034483 0.000000 0.620690 0.000000 0.034483 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.034483 0.000000 0.000000 0.931034 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.620690 0.000000 0.000000 0.000000 0.000000 0.000000 0.241379 0.034483 0.103448 0.000000 0.000000 0.000000 0.000000 0.172414 0.482759 0.000000 0.068966 0.034483 0.000000 0.137931 0.000000 0.000000 0.103448 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.034483 0.000000 0.000000 0.000000 0.000000 0.034483 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.931034 0.000000 0.000000 0.000000 0.000000 0.068966 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.034483 0.000000 0.034483 0.000000 0.000000 0.000000 0.000000 0.344828 0.241379 0.241379 0.034483 0.000000 0.000000 0.103448 0.034483 0.000000 0.000000 0.068966 0.000000 0.000000 0.000000 0.000000 0.000000 0.034483 0.000000 0.000000 0.000000 0.034483 0.448276 0.275862 0.000000 0.000000 0.000000 0.275862 0.000000 0.000000 0.000000 0.034483 0.034483 0.000000 0.137931 0.034483 0.103448 0.068966 0.000000 0.000000 0.000000 0.000000 0.034483 0.000000 0.275862 0.000000 0.000000 0.034483 0.000000 0.000000 0.000000 0.000000 0.034483 0.000000 0.000000 0.000000 0.000000 0.172414 0.000000 0.000000 0.000000 0.000000 0.000000 0.655172 0.103448 0.000000 0.000000 0.000000 0.000000 0.000000 0.241379 0.000000 0.000000 0.000000 0.000000 0.517241 0.000000 0.000000 0.000000 0.034483 0.000000 0.000000 0.172414 0.000000 0.000000 0.000000 0.034483 0.068966 0.000000 0.034483 0.034483 0.000000 0.034483 0.000000 0.000000 0.000000 0.103448 0.000000 0.000000 0.034483 0.000000 0.000000 0.551724 0.137931 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SKDALYSLESRSVTKS MEME-15 regular expression -------------------------------------------------------------------------------- S[KE][DS][AS]LYS[LS]ES[RST][ST][AV]T[KE]S -------------------------------------------------------------------------------- Time 489.48 secs. ******************************************************************************** ******************************************************************************** MOTIF KPPTFGSILEVEGFSPCTFKGKGGAVY MEME-16 width = 27 sites = 5 llr = 347 E-value = 1.1e-041 ******************************************************************************** -------------------------------------------------------------------------------- Motif KPPTFGSILEVEGFSPCTFKGKGGAVY MEME-16 Description -------------------------------------------------------------------------------- Simplified A :::2::::::::::::::::::::a2: pos.-specific C ::::::::::::::::a:::::::::2 probability D ::::::::::::::::::::::::::: matrix E :::::::::8:a::::::::2:::::: F ::::a::::::::8::::6:::::::: G :::::64:::::a:::::::6:88::: H ::::::::::::::::::::::::::: I :::::::a::::::::::::::::::: K a::::::::::::::::::8:a::::: L ::::::::4:::::::::2:::::::: M ::::::::::::::::::::::::::: N ::::::::::::::2:::::::::::2 P :aa:::::2::::::8::::2:::::: Q ::::::::22:::::::::2::::::: R ::::::::::::::::::::::::::: S :::::46:::::::82::2::::::2: T :::8::::2::::::::a::::2:::: V ::::::::::a::::::::::::::6: W :::::::::::::::::::::::2::: Y :::::::::::::2::::::::::::6 bits 6.8 6.1 5.4 * 4.8 ** * * * ** Relative 4.1 *** * * * ** ** * ** Entropy 3.4 ***** * **** *** * **** * (100.2 bits) 2.7 ******** ****************** 2.0 *************************** 1.4 *************************** 0.7 *************************** 0.0 --------------------------- Multilevel KPPTFGSILEVEGFSPCTFKGKGGAVY consensus A SG PQ YNS LQE TW AC sequence Q S P SN T -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KPPTFGSILEVEGFSPCTFKGKGGAVY MEME-16 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- --------------------------- XP_022747248.1 49 1.04e-35 HQCWKRSLSS KPPTFGGILEVEGFSPCTFKGKGGAVY DISETGSAKD XP_021289458.1 53 1.80e-32 HQCWNRSLPS KPPTFSSIQEVEGFSPCTFKGKGGAAY DVSETGSAED XP_022742854.1 53 3.75e-31 HHCWKQSLSL KPPTFGSILEVEGFSPCTLKEKGGAVY DVSETGSAKD XP_012442486.1 90 6.27e-29 HQCWKQSSSL KPPTFGSITQVEGFSPCTFQGKTWAVC DVLETGSAKD OMO66336.1 52 1.24e-23 HQCWNRSLEL KPPAFSGIPEVEGYNSCTSKPKGGASN YDVSETGSAK -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KPPTFGSILEVEGFSPCTFKGKGGAVY MEME-16 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- XP_022747248.1 1e-35 48_[16]_174 XP_021289458.1 1.8e-32 52_[16]_174 XP_022742854.1 3.7e-31 52_[16]_174 XP_012442486.1 6.3e-29 89_[16]_166 OMO66336.1 1.2e-23 51_[16]_171 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KPPTFGSILEVEGFSPCTFKGKGGAVY MEME-16 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF KPPTFGSILEVEGFSPCTFKGKGGAVY width=27 seqs=5 XP_022747248.1 ( 49) KPPTFGGILEVEGFSPCTFKGKGGAVY 1 XP_021289458.1 ( 53) KPPTFSSIQEVEGFSPCTFKGKGGAAY 1 XP_022742854.1 ( 53) KPPTFGSILEVEGFSPCTLKEKGGAVY 1 XP_012442486.1 ( 90) KPPTFGSITQVEGFSPCTFQGKTWAVC 1 OMO66336.1 ( 52) KPPAFSGIPEVEGYNSCTSKPKGGASN 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KPPTFGSILEVEGFSPCTFKGKGGAVY MEME-16 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 20 w= 27 n= 25541 bayes= 10.8532 E= 1.1e-041 -280 -369 -501 -472 -508 -412 -354 -339 395 -435 -391 -361 -402 -346 19 -502 -333 -386 -336 -447 -112 -333 -360 -365 -366 -289 -297 -307 -278 -314 -344 -348 444 -261 -239 -315 -222 -256 -347 -397 -112 -333 -360 -365 -366 -289 -297 -307 -278 -314 -344 -348 444 -261 -239 -315 -222 -256 -347 -397 147 -171 -363 -393 -323 -211 -294 -186 -277 -302 -218 -206 -278 -249 -223 -104 387 -127 -281 -352 -268 -252 -482 -500 445 -412 -355 -180 -436 -135 -211 -439 -366 -433 -382 -419 -361 -202 -110 -44 -40 -234 -280 -369 -402 363 -293 -359 -299 -410 -357 -209 -299 -305 -246 59 -190 -255 -309 -374 7 -175 -272 -359 -379 267 -278 -337 -295 -376 -335 -184 -264 -274 -251 187 -81 -216 -327 -363 -220 -289 -462 -479 -232 -403 -409 421 -371 -35 -90 -397 -410 -382 -341 -443 -228 135 -291 -298 -26 -189 -200 -153 -149 -185 -111 -37 -65 190 -63 -143 175 140 -45 -194 125 -24 -153 -163 -282 -554 -183 318 -556 -403 -374 -427 -319 -492 -462 -360 -430 -35 -343 -486 -368 -393 -477 -508 -61 -189 -424 -418 -263 -348 -321 62 -354 -161 -190 -392 -318 -357 -268 -408 -143 421 -315 -368 -411 -565 -256 327 -587 -477 -453 -473 -522 -581 -556 -439 -576 -355 -477 -610 -484 -480 -499 -569 -138 -344 -315 -403 -433 406 -327 -394 -319 -458 -394 -259 -356 -361 -255 -337 -316 -334 -303 -394 -267 -250 -478 -493 435 -411 -264 -183 -422 -138 -210 -413 -364 -403 -359 -413 -351 -202 -64 123 -79 -191 -226 -327 -320 -202 -230 -292 -226 -333 -285 51 -258 -240 -186 237 106 -275 -281 -293 -54 -284 -312 -314 -326 -244 -253 -259 -228 -269 -294 -293 424 -211 -192 -70 -168 -204 -322 -363 -306 552 -572 -558 -466 -496 -472 -365 -532 -452 -406 -514 -503 -501 -418 -546 -355 -401 -477 -527 -151 -240 -393 -447 -353 -313 -324 -214 -310 -340 -252 -232 -333 -289 -255 -142 418 -171 -302 -374 -224 -229 -459 -464 432 -386 -328 -140 -394 -39 -174 -406 -345 -389 -343 -208 -303 -156 -102 -28 -225 -357 -398 -325 -459 -344 -238 -307 379 -356 -322 -277 -352 37 54 -403 -256 -312 -300 -368 -101 -321 -218 -56 -393 375 -250 -339 -221 -388 -335 -183 56 -230 -191 -281 -234 -278 -287 -344 -280 -369 -501 -472 -508 -412 -354 -339 395 -435 -391 -361 -402 -346 19 -502 -333 -386 -336 -447 -97 -302 -293 -380 -414 394 -308 -364 -297 -430 -367 -233 -333 -333 -237 -297 17 -295 -293 -377 -126 -334 -303 -390 -398 397 -313 -375 -304 -439 -376 -246 -348 -347 -241 -324 -303 -318 227 -352 413 -118 -410 -400 -314 -140 -341 -233 -337 -279 -248 -344 -337 -323 -270 -177 -157 -90 -275 -356 146 -142 -378 -362 -242 -212 -271 22 -294 -170 -172 -314 -259 -279 -218 -58 -94 379 -258 -313 -91 189 -270 -289 127 -239 9 -132 -210 -153 -153 63 -245 -205 -152 -257 -165 -113 15 389 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KPPTFGSILEVEGFSPCTFKGKGGAVY MEME-16 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 20 w= 27 nsites= 5 E= 1.1e-041 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.800000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.600000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.400000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.400000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.600000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.400000 0.000000 0.000000 0.200000 0.200000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.800000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 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0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.600000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.800000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.600000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.800000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.800000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.600000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.600000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KPPTFGSILEVEGFSPCTFKGKGGAVY MEME-16 regular expression -------------------------------------------------------------------------------- KPP[TA]F[GS][SG]I[LPQT][EQ]VEG[FY][SN][PS]CT[FLS][KQ][GEP]K[GT][GW]A[VAS][YCN] -------------------------------------------------------------------------------- Time 512.67 secs. ******************************************************************************** ******************************************************************************** MOTIF GAGKDELAFVAGEHDLYHHDL MEME-17 width = 21 sites = 13 llr = 474 E-value = 3.5e-038 ******************************************************************************** -------------------------------------------------------------------------------- Motif GAGKDELAFVAGEHDLYHHDL MEME-17 Description -------------------------------------------------------------------------------- Simplified A :5::::15::5:::::1:::: pos.-specific C ::::::::::::::::2111: probability D ::2:5::::::1115:1:232 matrix E ::::26:::2128::::::2: F :1::::1:8::::::1:::12 G 8:7:1:::::281:2::1:11 H 2::::::::::::7:1184:: I :::::::::21::1::::::: K :::912::::1:::::::1:: L ::::::4::2:::::421::3 M ::::::::::::::::::::: N :::::1:1:::::11:::2:2 P ::::::22::::::121:::: Q :::::21:::::::11::1:: R 1:21:::::::::1::::::: S :2::::2:::1:::1:2:::1 T :2:::::2:::::::2::::: V ::::1:11:4:::::::::1: W ::::::::::::::::::::: Y ::::::::2:::::112:12: bits 6.8 6.1 5.4 4.8 Relative 4.1 * * * Entropy 3.4 * * * * * (52.6 bits) 2.7 **** ** *** * 2.0 ****** ******* * ** 1.4 ********************* 0.7 ********************* 0.0 --------------------- Multilevel GAGKDELAFVAGEHDLYHHDL consensus T E P IG ED sequence L -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAGKDELAFVAGEHDLYHHDL MEME-17 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- --------------------- XP_002531564.2 155 1.29e-23 CSMDDVTPTG GTGKDELPFLAGEHDLYHHYN ELHQNLEEAT XP_021650240.1 145 6.41e-23 LNSATATSTG GAGKDEPAFVAGEHDLYHYEL RQDLDEPIVE XP_021691173.1 123 4.66e-22 MSVCGGMFQC GTGKDELAFIAGEHDLYHNVL HQDLDEPNVK OAY41326.1 90 4.53e-21 LNSTMATSTV GAGKDESAFEAGEHGLHHHEL HQNLDEPIVE XP_021622766.1 133 2.64e-20 LHSTTATSTV GAGKDESAFEAGEHGLDHHEL HQNLDEPIVE XP_012074964.1 151 5.08e-16 CPLYDSTAPG GTGKGEPTFVAEEHYPLHKCN GLHQNFDDAI TKR66562.1 149 2.25e-15 HSADSAAAAQ HAGKEELTFVKGEIDQCGHDD GLQASQNLEE TKS09656.1 153 6.18e-14 YSPDNAAAPR HAGKEELVFVEEEDDHCCHYD GLQGYQNLEE GAY47919.1 182 6.18e-14 SSNSAAKTEG GSGKEQFNFVGDEHQTSHQFD DLNEHLTEFG XP_018806280.1 138 6.38e-13 GDLKDTDHSS GFRKDNLAFLIGERSTLHDGS RAFQNLDENL XP_028119329.1 133 1.60e-12 SLESRSFTKS GADRVQQPYIGGDHNFPHNDF GPHACLNFDE PSS23773.1 103 1.95e-12 SLDDISVTKS RADKKKAPYIGGEHDYALDDF GVHPCASFDD XP_023913884.1 146 6.98e-12 PSNCGKYYSL GSRKDKVAFLSGGNPPSHCDG LQAFQNAEDD -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAGKDELAFVAGEHDLYHHDL MEME-17 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- XP_002531564.2 1.3e-23 154_[17]_86 XP_021650240.1 6.4e-23 144_[17]_84 XP_021691173.1 4.7e-22 122_[17]_109 OAY41326.1 4.5e-21 89_[17]_85 XP_021622766.1 2.6e-20 132_[17]_84 XP_012074964.1 5.1e-16 150_[17]_86 TKR66562.1 2.2e-15 148_[17]_88 TKS09656.1 6.2e-14 152_[17]_88 GAY47919.1 6.2e-14 181_[17]_82 XP_018806280.1 6.4e-13 137_[17]_87 XP_028119329.1 1.6e-12 132_[17]_88 PSS23773.1 1.9e-12 102_[17]_80 XP_023913884.1 7e-12 145_[17]_79 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAGKDELAFVAGEHDLYHHDL MEME-17 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GAGKDELAFVAGEHDLYHHDL width=21 seqs=13 XP_002531564.2 ( 155) GTGKDELPFLAGEHDLYHHYN 1 XP_021650240.1 ( 145) GAGKDEPAFVAGEHDLYHYEL 1 XP_021691173.1 ( 123) GTGKDELAFIAGEHDLYHNVL 1 OAY41326.1 ( 90) GAGKDESAFEAGEHGLHHHEL 1 XP_021622766.1 ( 133) GAGKDESAFEAGEHGLDHHEL 1 XP_012074964.1 ( 151) GTGKGEPTFVAEEHYPLHKCN 1 TKR66562.1 ( 149) HAGKEELTFVKGEIDQCGHDD 1 TKS09656.1 ( 153) HAGKEELVFVEEEDDHCCHYD 1 GAY47919.1 ( 182) GSGKEQFNFVGDEHQTSHQFD 1 XP_018806280.1 ( 138) GFRKDNLAFLIGERSTLHDGS 1 XP_028119329.1 ( 133) GADRVQQPYIGGDHNFPHNDF 1 PSS23773.1 ( 103) RADKKKAPYIGGEHDYALDDF 1 XP_023913884.1 ( 146) GSRKDKVAFLSGGNPPSHCDG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAGKDELAFVAGEHDLYHHDL MEME-17 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 20 w= 21 n= 26237 bayes= 10.7336 E= 3.5e-038 -155 -367 -321 -410 -450 394 105 -408 -310 -474 -406 -263 -376 -363 -15 -350 -330 -350 -321 -405 358 -176 -478 -471 48 -192 -399 -297 -403 -344 -308 -389 -368 -373 -332 1 190 -159 -343 -417 -161 -372 -17 -393 -457 387 -323 -415 -313 -480 -414 -236 -374 -354 85 -343 -322 -357 -330 -409 -289 -376 -519 -491 -522 -427 -369 -345 395 -446 -400 -373 -412 -367 39 -516 -343 -396 -345 -461 -194 -478 287 106 -475 -10 -275 -378 -4 -406 -377 -192 -338 -161 -255 -371 -273 20 -409 -407 -183 -544 -138 249 -523 -325 -278 -389 124 -401 -369 29 -322 171 -174 -371 -260 -316 -448 -428 71 -182 -376 -328 71 -272 -225 -18 -235 208 -75 -278 146 54 -188 -14 -116 111 -166 -192 319 -226 -398 -382 -353 -222 -325 -250 -304 -308 -283 25 234 -286 -267 -259 154 75 -334 -369 -326 -304 -533 -550 437 -464 -295 -239 -476 -194 -266 -458 -419 -447 -406 -469 -404 -257 -98 159 -219 -277 -586 34 -266 -452 -438 257 -462 145 -179 -479 -457 -439 -403 -493 -246 308 -334 -354 356 -136 -291 -109 -286 100 -229 -4 -33 -244 -208 -242 -308 -184 -157 -93 -138 -82 -249 -295 -156 -373 -103 -65 -456 392 -326 -410 -315 -475 -408 -243 -370 -340 -265 -344 -322 -351 -327 -409 -393 -574 -189 325 -594 -261 -447 -475 -484 -576 -549 -426 -554 -335 -466 -591 -470 -474 -507 -570 -266 -290 -127 -361 -216 -329 478 -67 -345 -284 -250 -20 -313 -41 14 -325 -229 -282 -167 -47 -178 -392 245 -227 -404 125 -178 -372 -178 -386 -356 69 64 75 -181 -72 -187 -321 -359 88 -95 -206 -332 -288 74 -270 116 -46 -197 206 -96 -252 143 59 -163 -290 139 -33 -158 102 44 187 -61 -222 59 -238 113 -131 -141 32 -150 -198 14 -141 -112 -45 -134 -107 -64 312 -254 31 -301 -368 -217 -91 482 -333 -353 -119 -251 -111 -316 -47 -109 -326 -230 -276 -169 -51 -214 51 -17 -298 -230 -292 444 -322 -63 -282 -247 55 -294 46 -98 -298 -201 -266 -181 53 -68 130 156 80 65 15 -122 -128 -95 -176 -152 -156 -229 -95 -83 -228 -104 69 -181 190 -157 -344 143 -238 162 42 -178 -260 -174 166 -281 141 -294 -171 -174 -68 -171 -227 -317 -292 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAGKDELAFVAGEHDLYHHDL MEME-17 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 20 w= 21 nsites= 13 E= 3.5e-038 0.000000 0.000000 0.000000 0.000000 0.000000 0.769231 0.153846 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.076923 0.000000 0.000000 0.000000 0.000000 0.000000 0.538462 0.000000 0.000000 0.000000 0.076923 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.153846 0.230769 0.000000 0.000000 0.000000 0.000000 0.000000 0.153846 0.000000 0.000000 0.692308 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.153846 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.923077 0.000000 0.000000 0.000000 0.000000 0.000000 0.076923 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.538462 0.230769 0.000000 0.076923 0.000000 0.000000 0.076923 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.076923 0.000000 0.000000 0.000000 0.000000 0.000000 0.615385 0.000000 0.000000 0.000000 0.000000 0.153846 0.000000 0.000000 0.076923 0.000000 0.153846 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.076923 0.000000 0.000000 0.000000 0.076923 0.000000 0.000000 0.000000 0.000000 0.384615 0.000000 0.000000 0.153846 0.076923 0.000000 0.153846 0.000000 0.076923 0.000000 0.000000 0.461538 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.076923 0.230769 0.000000 0.000000 0.000000 0.153846 0.076923 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.846154 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.153846 0.000000 0.000000 0.000000 0.153846 0.000000 0.000000 0.000000 0.230769 0.000000 0.230769 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.384615 0.000000 0.000000 0.461538 0.000000 0.000000 0.076923 0.000000 0.230769 0.000000 0.076923 0.076923 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.076923 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.076923 0.153846 0.000000 0.769231 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.076923 0.846154 0.000000 0.076923 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.076923 0.000000 0.000000 0.000000 0.692308 0.076923 0.000000 0.000000 0.000000 0.076923 0.000000 0.000000 0.076923 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.461538 0.000000 0.000000 0.153846 0.000000 0.000000 0.000000 0.000000 0.000000 0.076923 0.076923 0.076923 0.000000 0.076923 0.000000 0.000000 0.000000 0.076923 0.000000 0.000000 0.000000 0.000000 0.076923 0.000000 0.076923 0.000000 0.000000 0.384615 0.000000 0.000000 0.153846 0.076923 0.000000 0.000000 0.153846 0.000000 0.000000 0.076923 0.076923 0.153846 0.076923 0.000000 0.000000 0.000000 0.076923 0.000000 0.000000 0.153846 0.000000 0.000000 0.076923 0.000000 0.000000 0.153846 0.000000 0.000000 0.000000 0.230769 0.000000 0.076923 0.000000 0.000000 0.000000 0.076923 0.769231 0.000000 0.000000 0.076923 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.076923 0.153846 0.000000 0.000000 0.000000 0.384615 0.000000 0.076923 0.000000 0.000000 0.153846 0.000000 0.076923 0.000000 0.000000 0.000000 0.000000 0.000000 0.076923 0.000000 0.076923 0.307692 0.230769 0.076923 0.076923 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.076923 0.000000 0.153846 0.000000 0.000000 0.230769 0.000000 0.153846 0.076923 0.000000 0.000000 0.000000 0.307692 0.000000 0.153846 0.000000 0.000000 0.000000 0.076923 0.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAGKDELAFVAGEHDLYHHDL MEME-17 regular expression -------------------------------------------------------------------------------- G[AT]GK[DE]EL[AP]F[VIL][AG]GEHDLYHH[DE][LD] -------------------------------------------------------------------------------- Time 535.42 secs. ******************************************************************************** ******************************************************************************** MOTIF DGMHDINIIEW MEME-18 width = 11 sites = 12 llr = 310 E-value = 2.3e-035 ******************************************************************************** -------------------------------------------------------------------------------- Motif DGMHDINIIEW MEME-18 Description -------------------------------------------------------------------------------- Simplified A ::::::::1:: pos.-specific C ::::::::::: probability D 91:23:::::: matrix E :3::2::::a: F ::1::1::::: G :4::::::::: H :::5::1:::: I ::1::3:a5:: K ::::1:1:::: L :::::2::::: M ::5:1:::::: N 1:::3:8:::: P ::::::::::: Q :::21:::::: R :2:2::::::: S ::::::::::: T :::::3::::: V ::3::1::4:: W ::::::::::a Y ::::::::::: bits 6.8 * 6.1 * 5.4 * 4.8 * * Relative 4.1 * * Entropy 3.4 * * ***** (37.3 bits) 2.7 * ** ***** 2.0 **** ****** 1.4 *********** 0.7 *********** 0.0 ----------- Multilevel DGMHDINIIEW consensus EV NT V sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif DGMHDINIIEW MEME-18 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- ----------- XP_013448883.1 19 1.11e-14 IPSQVNRFHV DEMHDINIIEW NKKRKLQGFQ XP_004514391.1 19 1.11e-14 IPSQLNRFKV DEMHDINIIEW NKKRKLHGYQ TKY63306.1 22 7.89e-14 NPSQGYRFCV DGVHETNIIEW NKKRKLQSDQ TKY66008.1 17 2.02e-13 NPSQVNRFQV DEMHNLNIVEW KKKRKLQIDQ XP_007134047.1 17 3.23e-13 NPSQGYRFCV DGVHKVNIIEW NKKRKFQSNQ PNX96427.1 2 4.02e-13 M DEMRDINIIEW NKKRKLQGFQ XP_019459351.1 19 5.60e-13 TPSQLNRFQT DRMQNINIVEW RNKRKLQSDQ XP_027336786.1 17 1.30e-12 NPSQGYRFCV DGVHETNIAEW NKKRKLQSDE XP_028783417.1 17 1.19e-11 NSSHPNRCYL DRFQQTNIVEW NKKRKLQTEQ XP_027353450.1 17 1.05e-10 NTSQVNRFEV DGMDNLKIIEW KKKRKLQTDQ XP_028773013.1 42 1.25e-10 FNPHLFRFQM DDVRMTHIVEW NKKRKLQIDQ XP_017416333.1 23 3.38e-10 RFHSLSRFQV NGIDDFNIVEW KKKRKLQSDQ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif DGMHDINIIEW MEME-18 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- XP_013448883.1 1.1e-14 18_[18]_184 XP_004514391.1 1.1e-14 18_[18]_209 TKY63306.1 7.9e-14 21_[18]_230 TKY66008.1 2e-13 16_[18]_199 XP_007134047.1 3.2e-13 16_[18]_224 PNX96427.1 4e-13 1_[18]_203 XP_019459351.1 5.6e-13 18_[18]_209 XP_027336786.1 1.3e-12 16_[18]_226 XP_028783417.1 1.2e-11 16_[18]_180 XP_027353450.1 1.1e-10 16_[18]_208 XP_028773013.1 1.2e-10 41_[18]_229 XP_017416333.1 3.4e-10 22_[18]_199 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif DGMHDINIIEW MEME-18 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF DGMHDINIIEW width=11 seqs=12 XP_013448883.1 ( 19) DEMHDINIIEW 1 XP_004514391.1 ( 19) DEMHDINIIEW 1 TKY63306.1 ( 22) DGVHETNIIEW 1 TKY66008.1 ( 17) DEMHNLNIVEW 1 XP_007134047.1 ( 17) DGVHKVNIIEW 1 PNX96427.1 ( 2) DEMRDINIIEW 1 XP_019459351.1 ( 19) DRMQNINIVEW 1 XP_027336786.1 ( 17) DGVHETNIAEW 1 XP_028783417.1 ( 17) DRFQQTNIVEW 1 XP_027353450.1 ( 17) DGMDNLKIIEW 1 XP_028773013.1 ( 42) DDVRMTHIVEW 1 XP_017416333.1 ( 23) NGIDDFNIVEW 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif DGMHDINIIEW MEME-18 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 20 w= 11 n= 27397 bayes= 11.6038 E= 2.3e-035 -257 -382 353 -166 -408 -330 -263 -353 -376 -412 -393 -57 -422 -335 -319 -404 -334 -323 -330 -366 -181 -493 33 171 -496 263 -248 -399 -186 -414 -383 -174 -314 -140 194 -325 -240 -327 -439 -403 -256 -306 -638 -599 97 -490 -461 139 -506 -90 394 -521 -483 -455 -435 -536 -282 287 -313 -353 -236 -315 14 -294 -253 -297 448 -340 -184 -300 -267 -114 -312 124 138 -314 -219 -285 -200 -90 -99 -374 180 85 -350 -229 -163 -279 56 -292 115 176 -244 95 -101 -250 -145 -221 -300 -282 -157 -226 -523 -477 91 -364 -332 290 -378 112 -104 -394 -375 -342 -307 -397 253 134 -226 -257 -293 -331 -252 -455 -362 -307 -13 -268 -170 -384 -343 394 -348 -256 -270 -262 -215 -304 -260 -338 -362 -412 -619 -655 -379 -518 -554 452 -553 -208 -264 -568 -535 -553 -506 -613 -382 -34 -439 -457 50 -307 -587 -590 -324 -505 -536 364 -496 -148 -199 -512 -505 -508 -467 -549 -279 309 -426 -419 -430 -572 -267 328 -596 -489 -465 -482 -554 -595 -569 -451 -597 -374 -495 -628 -501 -494 -506 -580 -359 -369 -481 -509 -154 -403 -382 -373 -421 -262 -330 -434 -437 -383 -321 -522 -387 -322 668 -181 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif DGMHDINIIEW MEME-18 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 20 w= 11 nsites= 12 E= 2.3e-035 0.000000 0.000000 0.916667 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.083333 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.083333 0.333333 0.000000 0.416667 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.166667 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.083333 0.000000 0.000000 0.083333 0.000000 0.000000 0.500000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.333333 0.000000 0.000000 0.000000 0.000000 0.166667 0.000000 0.000000 0.000000 0.500000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.166667 0.166667 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.333333 0.166667 0.000000 0.000000 0.000000 0.000000 0.083333 0.000000 0.083333 0.250000 0.000000 0.083333 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.083333 0.000000 0.000000 0.333333 0.000000 0.166667 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.333333 0.083333 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.083333 0.000000 0.083333 0.000000 0.000000 0.833333 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.083333 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.500000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.416667 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif DGMHDINIIEW MEME-18 regular expression -------------------------------------------------------------------------------- D[GE][MV]H[DN][IT]NI[IV]EW -------------------------------------------------------------------------------- Time 557.28 secs. ******************************************************************************** ******************************************************************************** MOTIF CDNDIEMKEESSGSCSEDKMISFESHLDYIYGTQNLEDFSEKDIENILYL MEME-19 width = 50 sites = 3 llr = 392 E-value = 3.9e-029 ******************************************************************************** -------------------------------------------------------------------------------- Motif CDNDIEMKEESSGSCSEDKMISFESHLDYIYGTQNLEDFSEKDIENILYL MEME-19 Description -------------------------------------------------------------------------------- Simplified A :::3:::::::::::::::::::::::::::::::::::::::::::::: pos.-specific C 7:::::::::::::a::::::::::::::::::::::::::::::::::: probability D :3:3:::::::::::::a:::::::::a:::::::::a::::7::::::: matrix E :3:3:7::aa::::::a::::::a::::::::::::a:::a:::7::::: F ::::::::::::::::::::::a:::::3:::::::::a::::::::::: G ::::::::::::a::3:::::::::::::::7:::::::::::::::::: H :::::::::::::::::::::::::a:::::::::::::::::::::::: I ::::7:::::::::::::::a::::::::a:::::::::::::a::a::: K :::::::a::::::::::a:::::::::::::3:3::::::a::3::::: L ::::::::::::::::::::::::::a::::::::a:::::::::::a:a M ::::::a::::::::::::a:::::::::::::::::::::::::::::: N :3a:::::::::::::::::::::::::::::::7::::::::::a:::: P :::::::::::::::::::::::::::::::::::::::::::::::::: Q :::::::::::::::::::::::::::::::::a:::::::::::::::: R :::::::::::::::::::::::::::::::::::::::::::::::::: S ::::::::::aa:a:7:::::7::a::::::3:::::::a:::::::::: T :::::::::::::::::::::3::::::::::7::::::::::::::::: V ::::33::::::::::::::::::::::::::::::::::::3::::::: W :::::::::::::::::::::::::::::::::::::::::::::::::: Y 3:::::::::::::::::::::::::::7:a:::::::::::::::::a: bits 6.8 6.1 5.4 * * * * 4.8 * * * ** * * ** * * * * * Relative 4.1 * * ** * * *** * * *** * * * * ** * Entropy 3.4 * * * **** * * ***** ** ****** ******* **** ***** (188.4 bits) 2.7 * * ********************************************** 2.0 ************************************************** 1.4 ************************************************** 0.7 ************************************************** 0.0 -------------------------------------------------- Multilevel CDNAIEMKEESSGSCSEDKMISFESHLDYIYGTQNLEDFSEKDIENILYL consensus YE DVV G T F SK K V K sequence N E -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CDNDIEMKEESSGSCSEDKMISFESHLDYIYGTQNLEDFSEKDIENILYL MEME-19 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------------------------------------------------- AAL35819.1 96 3.37e-58 SYVNSTTSME CNNDIEMKEESSGSCGEDKMISFESHLDYIYGTQNLEDFSEKVIENILYL DEQEEEEEDV KFK36656.1 90 2.95e-55 MSYVNSTSME YENEVEMKEESSGSCSEDKMISFESHLDYIYGKQNLEDFSEKDIENILYL EEEEEEEEEE XP_006410959.1 89 2.53e-54 TSYVNSSSME CDNAIVMKEESSGSCSEDKMITFESHLDFIYSTQKLEDFSEKDIKNILYL DEEDEEEANG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CDNDIEMKEESSGSCSEDKMISFESHLDYIYGTQNLEDFSEKDIENILYL MEME-19 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- AAL35819.1 3.4e-58 95_[19]_57 KFK36656.1 2.9e-55 89_[19]_58 XP_006410959.1 2.5e-54 88_[19]_53 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CDNDIEMKEESSGSCSEDKMISFESHLDYIYGTQNLEDFSEKDIENILYL MEME-19 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CDNDIEMKEESSGSCSEDKMISFESHLDYIYGTQNLEDFSEKDIENILYL width=50 seqs=3 AAL35819.1 ( 96) CNNDIEMKEESSGSCGEDKMISFESHLDYIYGTQNLEDFSEKVIENILYL 1 KFK36656.1 ( 90) YENEVEMKEESSGSCSEDKMISFESHLDYIYGKQNLEDFSEKDIENILYL 1 XP_006410959.1 ( 89) CDNAIVMKEESSGSCSEDKMITFESHLDFIYSTQKLEDFSEKDIKNILYL 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CDNDIEMKEESSGSCSEDKMISFESHLDYIYGTQNLEDFSEKDIENILYL MEME-19 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 20 w= 50 n= 22873 bayes= 13.3437 E= 3.9e-029 -234 538 -502 -496 -191 -409 -297 -261 -427 -322 -311 -423 -428 -402 -340 -453 -292 -265 -228 48 -132 -343 284 84 -355 -189 -152 -296 -158 -329 -302 107 -266 -124 -163 -251 -173 -248 -293 -287 -259 -315 -225 -406 -343 -273 -89 -258 -272 -367 -331 394 -325 -237 -249 -248 -198 -288 -248 -314 151 -339 215 156 -333 -183 -146 -245 -84 -269 -236 -105 -196 -36 -105 -231 -129 -177 -280 -264 -171 -245 -436 -445 -210 -380 -377 394 -342 -14 -67 -367 -378 -352 -309 -410 -184 228 -270 -277 -162 -380 -149 297 -370 -308 -267 -200 -206 -298 -289 -271 -314 -151 -213 -360 -228 59 -345 -348 -350 -358 -555 -576 -349 -465 -452 -185 -461 -168 506 -498 -457 -456 -440 -533 -372 -233 -249 -319 -265 -361 -473 -438 -492 -395 -332 -327 394 -417 -376 -342 -388 -313 27 -479 -315 -367 -326 -428 -391 -559 -246 327 -579 -464 -440 -464 -484 -566 -540 -425 -552 -337 -454 -588 -465 -466 -493 -556 -391 -559 -246 327 -579 -464 -440 -464 -484 -566 -540 -425 -552 -337 -454 -588 -465 -466 -493 -556 -46 -171 -306 -363 -305 -203 -267 -270 -247 -315 -273 -167 -247 -262 -193 250 105 -236 -265 -289 -46 -171 -306 -363 -305 -203 -267 -270 -247 -315 -273 -167 -247 -262 -193 250 105 -236 -265 -289 -115 -321 -292 -379 -411 403 -305 -369 -295 -433 -371 -236 -334 -337 -233 -313 -290 -309 -284 -371 -46 -171 -306 -363 -305 -203 -267 -270 -247 -315 -273 -167 -247 -262 -193 250 105 -236 -265 -289 -300 552 -568 -555 -462 -490 -469 -359 -527 -447 -402 -510 -499 -497 -415 -540 -351 -394 -473 -521 35 -148 -217 -279 -303 212 -208 -254 -200 -297 -256 -121 -207 -198 -163 188 41 -175 -257 -279 -391 -559 -246 327 -579 -464 -440 -464 -484 -566 -540 -425 -552 -337 -454 -588 -465 -466 -493 -556 -238 -367 352 -149 -392 -307 -247 -339 -348 -395 -378 -96 -395 -308 -297 -384 -312 -308 -315 -349 -265 -361 -473 -438 -492 -395 -332 -327 394 -417 -376 -342 -388 -313 27 -479 -315 -367 -326 -428 -350 -358 -555 -576 -349 -465 -452 -185 -461 -168 506 -498 -457 -456 -440 -533 -372 -233 -249 -319 -192 -265 -435 -446 -204 -378 -377 412 -338 -10 -64 -367 -382 -350 -308 -413 -199 158 -263 -269 -56 -163 -314 -368 -295 -230 -261 -239 -234 -299 -241 -152 -245 -248 -179 226 215 -219 -256 -287 -251 -239 -468 -484 442 -398 -330 -162 -417 -119 -193 -421 -352 -413 -364 -404 -341 -183 -94 -24 -391 -559 -246 327 -579 -464 -440 -464 -484 -566 -540 -425 -552 -337 -454 -588 -465 -466 -493 -556 -46 -171 -306 -363 -305 -203 -267 -270 -247 -315 -273 -167 -247 -262 -193 250 105 -236 -265 -289 -236 -276 -276 -337 -188 -289 491 -313 -287 -269 -244 -105 -290 -46 -96 -313 -216 -262 -147 -38 -209 -260 -481 -431 -104 -382 -311 4 -336 336 3 -400 -324 -274 -246 -431 -232 -45 -190 -243 -238 -367 352 -149 -392 -307 -247 -339 -348 -395 -378 -96 -395 -308 -297 -384 -312 -308 -315 -349 -130 -197 -335 -334 271 -284 12 -144 -256 -142 -158 -257 -265 -232 -177 -294 -205 -133 66 394 -192 -265 -435 -446 -204 -378 -377 412 -338 -10 -64 -367 -382 -350 -308 -413 -199 158 -263 -269 -177 -240 -363 -375 98 -297 -40 -183 -284 -184 -204 -282 -297 -262 -207 -338 -241 -173 30 449 -51 -258 -255 -335 -380 383 -267 -331 -258 -389 -332 -191 -288 -282 -207 -59 -200 -254 -275 -343 -57 -201 -205 -180 -258 -197 -130 -139 149 -210 -156 -108 -200 -71 8 -79 336 -98 -203 -226 -172 -304 -354 -169 -369 -344 -19 -285 -219 -237 -169 -240 -269 429 -119 -352 -236 -265 -221 -345 -145 -293 -145 -218 -313 -184 -70 -234 94 -292 -259 353 -248 -109 -49 -204 -129 -225 -229 -254 -209 -260 -481 -431 -104 -382 -311 4 -336 336 3 -400 -324 -274 -246 -431 -232 -45 -190 -243 -391 -559 -246 327 -579 -464 -440 -464 -484 -566 -540 -425 -552 -337 -454 -588 -465 -466 -493 -556 -238 -367 352 -149 -392 -307 -247 -339 -348 -395 -378 -96 -395 -308 -297 -384 -312 -308 -315 -349 -251 -239 -468 -484 442 -398 -330 -162 -417 -119 -193 -421 -352 -413 -364 -404 -341 -183 -94 -24 -46 -171 -306 -363 -305 -203 -267 -270 -247 -315 -273 -167 -247 -262 -193 250 105 -236 -265 -289 -391 -559 -246 327 -579 -464 -440 -464 -484 -566 -540 -425 -552 -337 -454 -588 -465 -466 -493 -556 -265 -361 -473 -438 -492 -395 -332 -327 394 -417 -376 -342 -388 -313 27 -479 -315 -367 -326 -428 -174 -326 336 -124 -339 -272 -220 -212 -265 -309 -300 -94 -331 -236 -236 -337 -238 17 -288 -307 -192 -265 -435 -446 -204 -378 -377 412 -338 -10 -64 -367 -382 -350 -308 -413 -199 158 -263 -269 -102 -391 -84 268 -378 -234 -172 -273 113 -294 -262 -174 -237 -51 -60 -275 -161 -217 -308 -302 -259 -315 -225 -406 -343 -273 -89 -258 -272 -367 -331 394 -325 -237 -249 -248 -198 -288 -248 -314 -192 -265 -435 -446 -204 -378 -377 412 -338 -10 -64 -367 -382 -350 -308 -413 -199 158 -263 -269 -209 -260 -481 -431 -104 -382 -311 4 -336 336 3 -400 -324 -274 -246 -431 -232 -45 -190 -243 -177 -240 -363 -375 98 -297 -40 -183 -284 -184 -204 -282 -297 -262 -207 -338 -241 -173 30 449 -209 -260 -481 -431 -104 -382 -311 4 -336 336 3 -400 -324 -274 -246 -431 -232 -45 -190 -243 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CDNDIEMKEESSGSCSEDKMISFESHLDYIYGTQNLEDFSEKDIENILYL MEME-19 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 20 w= 50 nsites= 3 E= 3.9e-029 0.000000 0.666667 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.333333 0.000000 0.000000 0.333333 0.333333 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.333333 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 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0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CDNDIEMKEESSGSCSEDKMISFESHLDYIYGTQNLEDFSEKDIENILYL MEME-19 regular expression -------------------------------------------------------------------------------- [CY][DEN]N[ADE][IV][EV]MKEESSGSC[SG]EDKMI[ST]FESHLD[YF]IY[GS][TK]Q[NK]LEDFSEK[DV]I[EK]NILYL -------------------------------------------------------------------------------- Time 580.21 secs. ******************************************************************************** ******************************************************************************** MOTIF PDSSSPSSDIEFAECSYAMEDTKTSDETS MEME-20 width = 29 sites = 6 llr = 366 E-value = 8.1e-022 ******************************************************************************** -------------------------------------------------------------------------------- Motif PDSSSPSSDIEFAECSYAMEDTKTSDETS MEME-20 Description -------------------------------------------------------------------------------- Simplified A 3:::::::::::a::::7::::::2:22: pos.-specific C ::::3:::::::::a:::::::::::::: probability D :72:::::823::::::::23::::3::: matrix E ::::::::::7::a:::::52:::::7:: F :::::3:::::5:::2::::::::::::: G :::::::3::::::::::::::::3:::: H :::3::::::::::::::::::::::::: I :3:::::::7:::::::::::::2::::: K ::::::::::::::::::::::a::3::: L :::::::::::::::::::::::::::2: M ::::::::::::::::::7:::::::::: N ::::::::::::::::2:::3::2:2::: P 3::::7::::::::::::::::::::::: Q ::::::::::::::::::::::::::::: R ::::2:::::::::::::::::::::::: S 2:875:a7:::3:::8:2:::2::5::2a T :::::::::::::::::23::7:7::25: V 2:::::::2:::::::::::::::::::: W ::::::::::::::::::::::::::::: Y :::::::::2:2::::8::322:::2::: bits 6.8 6.1 5.4 * 4.8 * Relative 4.1 * * * * * Entropy 3.4 * * ** *** * * ** (88.0 bits) 2.7 ******************* *** * * 2.0 ***************************** 1.4 ***************************** 0.7 ***************************** 0.0 ----------------------------- Multilevel ADSSSPSSDIEFAECSYAMEDTKTSDETS consensus PI HCF G DS TYN GK sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif PDSSSPSSDIEFAECSYAMEDTKTSDETS MEME-20 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- ----------------------------- RID43060.1 60 2.52e-30 FCLEQQQALL PDSSSPSSDIESAECFYAMEDTKTGDETS SSSASVCMSK XP_006398684.1 58 2.94e-29 KHFCLEQAAH PDSSCPSSDIESAECSYAMEYTKNSDETS SSASGTVASS KFK24705.1 41 6.94e-29 FCMEQQQASL SDSSCPSSDIEFAECSYTMDNTKTSNETS SSASVTKASS OAO95598.1 59 1.11e-26 HFCSEQQASL VDSSRPSSVIDYAECSYAMENTKTSYEAS SSASFTGPSL XP_010558336.1 74 4.31e-25 KLPETESGIT AISHSFSGDDEFAECSYATYDYKTAKASS DESTPSASNT XP_010543288.1 77 6.56e-20 KSPETTESDM AIDHSFSGDYDFAECSNSTYESKIGKTLS DGSSPFEVIC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif PDSSSPSSDIEFAECSYAMEDTKTSDETS MEME-20 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- RID43060.1 2.5e-30 59_[20]_108 XP_006398684.1 2.9e-29 57_[20]_116 KFK24705.1 6.9e-29 40_[20]_105 OAO95598.1 1.1e-26 58_[20]_114 XP_010558336.1 4.3e-25 73_[20]_135 XP_010543288.1 6.6e-20 76_[20]_95 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif PDSSSPSSDIEFAECSYAMEDTKTSDETS MEME-20 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF PDSSSPSSDIEFAECSYAMEDTKTSDETS width=29 seqs=6 RID43060.1 ( 60) PDSSSPSSDIESAECFYAMEDTKTGDETS 1 XP_006398684.1 ( 58) PDSSCPSSDIESAECSYAMEYTKNSDETS 1 KFK24705.1 ( 41) SDSSCPSSDIEFAECSYTMDNTKTSNETS 1 OAO95598.1 ( 59) VDSSRPSSVIDYAECSYAMENTKTSYEAS 1 XP_010558336.1 ( 74) AISHSFSGDDEFAECSYATYDYKTAKASS 1 XP_010543288.1 ( 77) AIDHSFSGDYDFAECSNSTYESKIGKTLS 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif PDSSSPSSDIEFAECSYAMEDTKTSDETS MEME-20 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 20 w= 29 n= 25309 bayes= 11.7009 E= 8.1e-022 252 -175 -336 -317 -292 -169 -260 -196 -238 -243 -230 -277 318 -218 -199 -13 -122 130 -277 -315 -213 -341 327 -167 -345 -303 -261 163 -312 -292 -304 -131 -380 -281 -284 -373 -272 -148 -318 -332 -99 -218 15 -287 -345 -202 -229 -319 -234 -357 -312 -106 -271 -238 -204 240 72 -295 -303 -310 -94 -252 -214 -299 -295 -191 317 -327 -203 -354 -328 -128 -288 -217 -179 211 -51 -268 -273 -232 -11 322 -311 -324 -314 -174 -241 -242 -165 -288 -253 -198 -255 -203 163 184 9 -178 -277 -299 -115 -323 -368 -372 220 -294 -267 -266 -283 -270 -302 -343 408 -263 -242 -318 -222 -232 -236 -185 -116 -237 -398 -473 -381 -270 -352 -359 -345 -398 -357 -252 -322 -356 -280 270 27 -319 -332 -368 -10 -188 -309 -401 -401 233 -311 -364 -336 -401 -360 -214 -285 -307 -285 214 -82 -237 -353 -391 -242 -370 350 -154 -395 -320 -255 -325 -360 -393 -377 -102 -408 -319 -306 -393 -319 -105 -320 -355 -180 -268 -100 -384 -172 -345 -298 397 -296 -25 -72 -313 -359 -299 -265 -374 -188 138 -205 36 -178 -561 116 287 -537 -318 -299 -384 -209 -416 -386 -266 -318 -119 -269 -382 -272 -315 -469 -455 -242 -271 -445 -453 371 -377 -123 -205 -366 -187 -228 -346 -362 -327 -287 46 -297 -205 -5 246 418 -139 -433 -426 -336 -160 -362 -258 -363 -303 -272 -366 -353 -346 -293 -197 -177 -113 -296 -378 -416 -567 -258 327 -589 -480 -456 -475 -531 -585 -559 -442 -582 -360 -482 -615 -489 -484 -501 -571 -308 552 -573 -559 -467 -498 -473 -366 -533 -453 -408 -516 -505 -502 -419 -548 -357 -403 -478 -529 -83 -192 -356 -421 70 -251 -276 -268 -285 -306 -274 -196 -283 -298 -223 244 92 -251 -221 -186 -199 -274 -324 -374 69 -305 -64 -231 -290 -230 -245 105 -328 -275 -228 -341 -259 -216 -4 435 383 -97 -390 -378 -299 -120 -320 -222 -311 -264 -227 -316 -319 -296 -248 -28 83 -72 -263 -344 -118 -234 -440 -424 -210 -291 -326 -65 -304 -101 443 -339 -347 -306 -260 -301 220 -67 -232 -266 -104 -428 98 218 -314 -223 -183 -304 -119 -321 -291 -146 -241 -62 -156 -271 -173 -236 -318 262 -139 -343 253 24 -352 -164 -139 -318 -151 -343 -316 184 -265 -137 -155 -226 -158 -270 -305 127 -121 -202 -340 -387 -291 -301 -269 -170 -250 -294 -196 -174 -300 -230 -203 13 380 -129 -254 88 -284 -372 -507 -480 -513 -416 -360 -342 396 -440 -396 -366 -406 -354 15 -507 -337 -391 -340 -452 -129 -202 -342 -384 -296 -313 -270 81 -246 -270 -182 37 -301 -227 -200 -89 383 -106 -258 -326 198 -156 -379 -424 -394 242 -342 -343 -361 -382 -336 -275 -269 -312 -292 170 -104 -198 -347 -406 -74 -300 176 -127 -289 -130 -89 -252 197 -265 -231 135 -206 -64 -50 -175 -92 -201 -247 162 105 -375 -106 270 -411 -251 -231 -300 -151 -332 -299 -219 -269 -96 -175 -292 91 -235 -362 -355 109 -179 -333 -339 -263 -243 -248 -133 -224 9 -168 -187 -270 -208 -181 33 344 -95 -237 -286 -116 -237 -398 -473 -381 -270 -352 -359 -345 -398 -357 -252 -322 -356 -280 270 27 -319 -332 -368 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif PDSSSPSSDIEFAECSYAMEDTKTSDETS MEME-20 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 20 w= 29 nsites= 6 E= 8.1e-022 0.333333 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.333333 0.000000 0.000000 0.166667 0.000000 0.166667 0.000000 0.000000 0.000000 0.000000 0.666667 0.000000 0.000000 0.000000 0.000000 0.333333 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.166667 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.833333 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.333333 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.666667 0.000000 0.000000 0.000000 0.000000 0.000000 0.333333 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.166667 0.500000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.333333 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.666667 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.333333 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.666667 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.833333 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.166667 0.000000 0.000000 0.000000 0.000000 0.166667 0.000000 0.000000 0.000000 0.000000 0.666667 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.166667 0.000000 0.000000 0.333333 0.666667 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.500000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.333333 0.000000 0.000000 0.000000 0.166667 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.166667 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.833333 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.166667 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.833333 0.666667 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.166667 0.166667 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.666667 0.000000 0.000000 0.000000 0.000000 0.000000 0.333333 0.000000 0.000000 0.000000 0.000000 0.000000 0.166667 0.500000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.333333 0.000000 0.000000 0.333333 0.166667 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.333333 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.166667 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.166667 0.666667 0.000000 0.000000 0.166667 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.166667 0.000000 0.000000 0.000000 0.166667 0.000000 0.000000 0.000000 0.000000 0.666667 0.000000 0.000000 0.000000 0.166667 0.000000 0.000000 0.000000 0.000000 0.333333 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.500000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.333333 0.000000 0.000000 0.000000 0.000000 0.000000 0.333333 0.000000 0.000000 0.166667 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.166667 0.166667 0.000000 0.000000 0.666667 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.166667 0.000000 0.000000 0.000000 0.166667 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.166667 0.000000 0.000000 0.000000 0.000000 0.000000 0.166667 0.500000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif PDSSSPSSDIEFAECSYAMEDTKTSDETS MEME-20 regular expression -------------------------------------------------------------------------------- [AP][DI]S[SH][SC][PF]S[SG]DI[ED][FS]AECSYA[MT][EY][DN]TKT[SG][DK]ETS -------------------------------------------------------------------------------- Time 602.87 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- AAL35819.1 1.85e-87 5_[10(1.63e-10)]_19_[3(1.43e-10)]_4_\ [7(3.18e-06)]_29_[19(3.37e-58)]_19_[2(5.99e-16)]_2_[1(1.03e-23)] OAO95598.1 1.62e-47 31_[3(8.89e-10)]_1_[7(1.28e-06)]_3_\ [20(1.11e-26)]_12_[15(2.14e-07)]_49_[2(3.51e-11)]_1_[1(3.36e-22)] RVW33794.1 7.84e-106 33_[3(6.45e-18)]_[7(3.16e-09)]_4_\ [14(7.56e-12)]_12_[4(2.19e-12)]_[8(9.33e-15)]_1_[11(5.22e-12)]_4_\ [15(2.32e-09)]_19_[6(2.79e-18)]_8_[5(6.68e-10)]_2_[2(8.21e-20)]_\ [1(1.58e-25)] XP_012074964.1 7.35e-100 1_[10(3.88e-09)]_13_[3(5.36e-17)]_\ [7(2.89e-08)]_1_[14(1.05e-06)]_11_[4(6.47e-18)]_[8(5.31e-10)]_1_\ [11(1.21e-09)]_19_[17(5.08e-16)]_4_[6(6.69e-15)]_8_[5(4.29e-10)]_2_\ [2(2.17e-19)]_[1(1.38e-23)] XP_021650240.1 1.75e-121 15_[3(1.88e-16)]_[7(1.55e-09)]_4_\ [14(2.58e-13)]_12_[4(3.91e-13)]_[8(1.12e-09)]_3_[11(2.48e-08)]_4_\ [15(6.67e-11)]_1_[17(6.41e-23)]_2_[6(1.32e-15)]_8_[5(7.40e-16)]_2_\ [2(8.21e-20)]_[1(3.08e-26)] XP_015896979.1 3.03e-110 [10(1.80e-12)]_8_[3(1.84e-15)]_\ [7(5.78e-08)]_4_[14(2.67e-11)]_12_[4(1.40e-12)]_[8(2.59e-11)]_1_\ [11(5.79e-12)]_1_[15(4.79e-10)]_20_[6(2.14e-16)]_6_[5(9.77e-14)]_2_\ [2(7.63e-19)]_[1(2.00e-26)] XP_021622766.1 1.23e-127 5_[3(3.95e-17)]_[7(1.55e-09)]_4_\ [14(1.19e-14)]_12_[4(1.04e-15)]_[8(3.12e-13)]_1_[11(2.58e-06)]_4_\ [15(1.09e-11)]_1_[17(2.64e-20)]_2_[6(2.17e-17)]_8_[5(1.65e-18)]_2_\ [2(8.21e-20)]_[1(1.23e-27)] XP_010528448.1 1.04e-50 3_[10(2.89e-10)]_14_[3(1.46e-12)]_1_\ [7(1.62e-07)]_11_[4(2.95e-09)]_1_[19(5.04e-05)]_10_[2(1.50e-16)]_1_\ [1(4.49e-26)] XP_022742854.1 5.39e-119 1_[10(1.89e-07)]_10_[3(7.91e-14)]_\ [7(1.65e-08)]_3_[16(3.75e-31)]_4_[4(2.51e-15)]_[8(7.42e-11)]_1_\ [11(4.28e-11)]_42_[6(3.12e-19)]_8_[5(1.01e-11)]_2_[2(2.32e-18)]_\ [1(1.33e-26)] PON90845.1 6.45e-92 [10(1.97e-10)]_8_[3(2.18e-16)]_\ [7(6.95e-09)]_31_[4(3.45e-13)]_[8(6.82e-12)]_6_[20(6.95e-06)]_21_\ [6(3.97e-22)]_8_[5(3.76e-11)]_2_[2(2.17e-19)]_[1(4.15e-24)] XP_021691173.1 7.42e-91 35_[3(1.97e-14)]_[7(4.25e-06)]_4_\ [14(8.87e-13)]_12_[4(1.27e-14)]_12_[17(4.66e-22)]_2_[6(3.02e-13)]_8_\ [5(5.30e-18)]_2_[2(1.88e-17)]_[1(1.86e-24)]_25 XP_012442486.1 5.19e-99 63_[3(2.58e-15)]_[7(4.33e-09)]_3_\ [16(6.27e-29)]_4_[4(3.35e-14)]_[8(8.29e-09)]_50_[6(2.14e-16)]_8_\ [5(1.01e-11)]_2_[2(1.73e-18)]_[1(4.03e-25)] OVA17828.1 8.75e-53 31_[3(1.73e-12)]_[7(3.76e-07)]_41_\ [8(3.63e-10)]_17_[11(2.97e-13)]_43_[6(3.88e-07)]_9_[5(2.18e-06)]_2_\ [2(2.17e-17)]_[1(2.57e-24)] XP_010529822.1 1.59e-47 3_[10(2.64e-11)]_14_[3(5.06e-11)]_1_\ [7(8.88e-06)]_24_[4(6.49e-09)]_7_[19(2.15e-06)]_10_[2(1.82e-14)]_1_\ [1(4.83e-24)] XP_002531564.2 1.00e-106 1_[10(8.21e-09)]_13_[3(6.40e-16)]_\ [7(4.33e-11)]_4_[14(1.28e-12)]_12_[4(2.53e-14)]_[8(1.04e-13)]_35_\ [17(1.29e-23)]_4_[6(6.02e-15)]_8_[5(1.12e-08)]_2_[2(7.11e-18)]_\ [1(8.04e-25)] XP_010256878.1 2.24e-57 [10(8.77e-10)]_13_[3(4.65e-06)]_\ [7(2.88e-06)]_35_[4(8.89e-13)]_13_[11(3.00e-10)]_48_[6(1.59e-08)]_10_\ [5(2.61e-08)]_2_[2(6.08e-18)]_[1(2.22e-25)] XP_007134047.1 1.49e-105 [10(1.12e-11)]_1_[18(3.23e-13)]_1_\ [3(3.54e-13)]_[7(8.04e-10)]_4_[14(7.83e-17)]_8_[4(1.50e-08)]_[8(1.07e-11)]_\ 32_[13(7.29e-27)]_1_[6(5.83e-07)]_18_[2(1.98e-18)]_[1(2.57e-24)] XP_023913884.1 3.54e-107 [10(1.23e-13)]_13_[3(2.94e-17)]_\ [7(1.65e-08)]_4_[14(1.76e-11)]_13_[4(2.71e-13)]_[8(5.28e-13)]_1_\ [11(1.61e-12)]_10_[17(6.98e-12)]_5_[6(7.54e-08)]_[5(8.68e-10)]_2_\ [2(3.77e-17)]_[1(3.59e-27)] XP_006410959.1 2.19e-91 3_[10(2.88e-12)]_17_[3(8.41e-12)]_3_\ [7(3.76e-07)]_8_[11(7.45e-05)]_4_[19(2.53e-54)]_16_[2(2.61e-16)]_1_\ [1(1.06e-25)] TKY63306.1 2.11e-118 5_[10(2.88e-12)]_1_[18(7.89e-14)]_1_\ [3(2.04e-13)]_[7(1.65e-08)]_4_[14(2.84e-16)]_8_[4(3.62e-10)]_[8(3.86e-09)]_\ 1_[11(1.07e-11)]_16_[13(3.37e-28)]_1_[6(7.02e-13)]_24_[2(2.51e-19)]_\ [1(3.22e-23)] XP_027336786.1 1.81e-130 [10(1.92e-11)]_1_[18(1.30e-12)]_1_\ [3(1.06e-14)]_[7(1.43e-08)]_4_[14(9.62e-14)]_8_[4(1.09e-14)]_[8(1.07e-11)]_\ 1_[11(3.34e-13)]_16_[13(4.34e-29)]_1_[6(1.13e-14)]_3_[5(1.31e-08)]_2_\ [2(2.17e-19)]_[1(9.57e-25)] XP_022747248.1 1.10e-120 1_[10(9.67e-09)]_6_[3(1.16e-13)]_\ [7(2.67e-09)]_3_[16(1.04e-35)]_4_[4(9.71e-14)]_[8(1.45e-12)]_1_\ [11(1.60e-07)]_3_[15(7.64e-05)]_23_[6(1.87e-18)]_8_[5(2.93e-13)]_2_\ [2(8.78e-16)]_[1(4.03e-25)] VDD15356.1 2.30e-47 224_[3(2.05e-10)]_3_[7(2.34e-07)]_\ 26_[19(1.48e-20)]_17_[2(3.02e-15)]_1_[1(3.00e-24)] TKY66008.1 3.09e-126 [10(2.11e-13)]_1_[18(2.02e-13)]_1_\ [3(3.22e-15)]_[7(4.76e-10)]_4_[14(1.07e-14)]_2_[4(7.03e-15)]_[8(1.51e-14)]_\ 6_[13(4.36e-25)]_1_[6(1.65e-15)]_8_[5(4.18e-13)]_2_[2(2.51e-19)]_\ [1(8.79e-22)] XP_024189435.1 1.57e-91 3_[10(7.66e-06)]_10_[3(1.14e-18)]_\ [7(3.16e-09)]_39_[4(2.19e-12)]_1_[8(7.64e-12)]_[11(1.30e-12)]_4_\ [15(7.76e-07)]_19_[6(1.16e-17)]_8_[5(1.17e-12)]_2_[2(2.17e-19)]_1_\ [1(4.84e-22)] TKR66562.1 1.37e-111 25_[3(1.28e-13)]_[7(4.33e-11)]_4_\ [14(7.94e-10)]_12_[4(5.95e-17)]_[8(1.20e-11)]_1_[11(1.15e-13)]_17_\ [17(2.25e-15)]_6_[6(1.65e-15)]_8_[5(5.30e-18)]_2_[2(3.85e-15)]_\ [1(8.85e-26)] KFK36656.1 4.91e-82 4_[10(4.99e-09)]_17_[3(8.41e-12)]_3_\ [7(2.06e-07)]_27_[19(2.95e-55)]_21_[2(5.99e-16)]_1_[1(1.25e-20)] PIA54706.1 2.41e-55 29_[3(5.99e-09)]_[7(1.78e-05)]_11_\ [5(2.95e-06)]_13_[4(5.81e-11)]_[8(6.55e-08)]_17_[11(8.58e-10)]_4_\ [15(6.93e-06)]_8_[6(1.65e-10)]_9_[5(5.51e-05)]_1_[2(2.04e-14)]_\ [1(4.15e-24)] RXI02216.1 8.03e-92 2_[10(4.44e-11)]_21_[3(2.67e-14)]_\ [7(1.43e-08)]_5_[14(3.13e-13)]_12_[4(1.35e-10)]_[8(1.36e-10)]_1_\ [11(2.39e-11)]_1_[17(9.34e-06)]_6_[6(2.17e-17)]_8_[5(4.29e-10)]_2_\ [2(8.64e-18)]_2_[1(4.84e-22)] TEY25303.1 3.56e-59 [10(1.64e-09)]_3_[3(1.40e-13)]_\ [7(2.53e-08)]_28_[4(1.66e-07)]_[8(1.28e-07)]_20_[15(9.65e-06)]_28_\ [6(7.05e-09)]_6_[5(6.33e-08)]_2_[2(3.35e-17)]_[1(1.35e-24)] XP_008240727.1 1.84e-103 [10(7.32e-10)]_8_[3(1.96e-18)]_\ [7(9.64e-10)]_5_[14(9.88e-18)]_12_[4(5.59e-13)]_[8(2.41e-14)]_1_\ [11(2.74e-10)]_15_[6(2.70e-19)]_8_[5(4.65e-09)]_2_[2(2.11e-15)]_4_\ [1(3.81e-22)] XP_026417177.1 4.88e-48 29_[3(4.65e-13)]_[7(5.97e-07)]_27_\ [8(2.50e-09)]_17_[11(1.65e-13)]_36_[6(1.09e-06)]_24_[2(3.17e-13)]_\ [1(1.03e-23)] XP_028773013.1 1.24e-107 41_[18(1.25e-10)]_1_[3(1.17e-14)]_\ [7(3.11e-11)]_4_[14(4.01e-11)]_12_[4(3.05e-13)]_[8(8.47e-10)]_1_\ [11(3.81e-12)]_10_[13(7.20e-24)]_1_[6(5.40e-11)]_8_[5(2.60e-13)]_2_\ [2(3.82e-18)]_[1(2.45e-23)] XP_006349495.1 2.07e-77 2_[10(2.73e-06)]_13_[3(9.96e-18)]_\ [7(1.42e-06)]_35_[4(1.99e-11)]_14_[11(3.20e-11)]_4_[15(2.08e-15)]_27_\ [6(6.69e-15)]_8_[5(3.52e-08)]_1_[2(4.54e-18)]_[1(1.57e-21)] XP_009798034.1 6.83e-96 [10(7.32e-10)]_13_[3(1.47e-16)]_\ [7(2.14e-06)]_35_[4(1.48e-15)]_14_[11(1.80e-12)]_4_[15(1.82e-14)]_\ [17(8.97e-06)]_6_[6(7.21e-19)]_8_[5(2.40e-16)]_2_[2(3.41e-15)]_\ [1(2.45e-23)] XP_021289458.1 8.53e-123 1_[10(2.69e-07)]_10_[3(3.59e-15)]_\ [7(1.33e-09)]_3_[16(1.80e-32)]_4_[4(4.97e-13)]_[8(2.10e-12)]_1_\ [11(1.69e-09)]_3_[15(1.39e-09)]_23_[6(1.09e-18)]_8_[5(2.60e-13)]_2_\ [2(4.34e-17)]_[1(1.14e-24)] XP_027353450.1 5.45e-120 [10(3.61e-11)]_1_[18(1.05e-10)]_1_\ [3(2.30e-15)]_[7(9.28e-09)]_4_[14(3.05e-17)]_12_[4(2.21e-14)]_\ [8(1.29e-14)]_6_[13(1.35e-30)]_[6(1.24e-07)]_8_[5(4.56e-14)]_2_\ [2(3.82e-18)]_[1(4.84e-22)] XP_017416333.1 1.29e-115 [10(1.61e-14)]_7_[18(3.38e-10)]_1_\ [3(6.94e-15)]_[7(4.76e-10)]_4_[14(1.62e-11)]_2_[4(2.02e-16)]_[8(2.24e-10)]_\ 6_[13(3.29e-25)]_1_[6(3.30e-11)]_8_[5(1.31e-12)]_2_[2(2.51e-19)]_\ [1(4.84e-22)] PKI43461.1 3.48e-57 32_[3(1.64e-15)]_[7(4.75e-07)]_3_\ [14(7.77e-05)]_9_[4(1.01e-09)]_6_[11(1.48e-06)]_39_[6(1.43e-11)]_4_\ [5(3.28e-10)]_2_[2(5.52e-15)]_[1(3.00e-24)] XP_004302767.1 1.87e-86 3_[10(3.55e-07)]_8_[3(1.66e-18)]_\ [7(3.16e-09)]_39_[4(1.33e-11)]_1_[8(8.47e-10)]_[11(1.31e-11)]_4_\ [15(1.63e-06)]_19_[6(1.69e-17)]_8_[5(1.17e-12)]_2_[2(1.73e-18)]_1_\ [1(4.84e-22)] XP_022846646.1 1.50e-93 [10(1.32e-07)]_8_[3(5.01e-15)]_\ [7(4.75e-07)]_24_[4(3.91e-13)]_[8(2.46e-07)]_1_[11(1.45e-11)]_2_\ [15(6.45e-15)]_[17(2.33e-05)]_6_[6(2.03e-19)]_8_[5(6.02e-12)]_2_\ [2(1.64e-17)]_2_[1(2.57e-24)] XP_024028595.1 8.50e-87 [10(7.38e-11)]_8_[3(1.64e-15)]_\ [7(2.21e-09)]_35_[4(1.02e-10)]_[8(2.10e-12)]_43_[6(8.47e-20)]_8_\ [5(6.37e-16)]_2_[2(1.21e-13)]_[1(1.87e-25)] XP_022983598.1 5.10e-83 27_[3(7.91e-14)]_[7(1.93e-06)]_4_\ [14(4.25e-14)]_12_[4(1.68e-14)]_[8(3.97e-11)]_18_[15(1.74e-09)]_20_\ [6(1.11e-11)]_8_[5(1.81e-13)]_2_[2(3.02e-15)]_[1(2.12e-23)] XP_010047842.1 2.90e-72 12_[3(1.69e-13)]_[7(1.55e-09)]_2_\ [14(3.89e-05)]_12_[4(1.33e-11)]_[8(3.04e-07)]_18_[15(7.96e-05)]_27_\ [6(1.02e-17)]_8_[5(1.13e-09)]_2_[2(1.74e-16)]_[1(5.65e-24)] OUZ99277.1 3.53e-62 15_[3(3.22e-15)]_[7(3.76e-07)]_20_\ [4(2.51e-09)]_[8(5.21e-08)]_1_[11(2.92e-14)]_42_[6(3.08e-10)]_26_\ [2(2.30e-13)]_[1(3.71e-23)] PIN04755.1 2.73e-69 [10(7.32e-10)]_3_[3(1.17e-14)]_\ [7(2.89e-08)]_28_[4(1.62e-10)]_16_[11(5.56e-08)]_4_[15(8.57e-13)]_39_\ [5(6.68e-10)]_2_[2(1.19e-17)]_[1(1.83e-23)] XP_011077640.1 3.02e-72 53_[10(6.10e-10)]_3_[3(1.97e-14)]_\ [7(1.33e-09)]_28_[4(7.72e-11)]_[8(1.75e-09)]_2_[11(7.09e-05)]_4_\ [15(3.37e-12)]_43_[5(2.07e-14)]_2_[2(7.63e-19)]_[1(4.28e-21)] PHT70537.1 1.61e-73 42_[3(9.96e-18)]_[7(5.33e-07)]_35_\ [4(1.02e-10)]_14_[11(2.90e-11)]_4_[15(1.18e-13)]_27_[6(4.71e-18)]_8_\ [5(3.79e-08)]_1_[2(4.54e-18)]_[1(4.78e-21)] XP_022145567.1 2.13e-89 [10(5.28e-14)]_13_[3(4.03e-15)]_\ [7(1.16e-05)]_4_[14(1.07e-12)]_12_[4(3.03e-10)]_[8(1.07e-11)]_14_\ [15(3.61e-11)]_18_[6(2.49e-13)]_8_[5(4.38e-12)]_2_[2(5.52e-15)]_\ [1(7.82e-22)] PIN03316.1 1.01e-65 [10(5.85e-08)]_3_[3(3.24e-13)]_\ [7(8.00e-09)]_23_[4(1.94e-10)]_16_[11(4.28e-14)]_47_[5(1.25e-13)]_2_\ [2(2.17e-17)]_[1(2.98e-22)] OMO66336.1 6.46e-92 1_[10(1.15e-05)]_9_[3(3.24e-13)]_\ [7(1.33e-09)]_3_[16(1.24e-23)]_5_[4(1.57e-12)]_13_[11(4.25e-05)]_2_\ [15(2.70e-08)]_23_[6(2.10e-14)]_8_[5(1.01e-11)]_2_[2(2.32e-18)]_\ [1(2.46e-21)] XP_023734875.1 2.24e-61 22_[3(4.95e-09)]_[7(1.28e-06)]_17_\ [4(4.42e-13)]_[8(7.62e-09)]_1_[11(2.77e-12)]_49_[5(2.28e-10)]_2_\ [2(1.32e-16)]_[1(1.83e-23)] GAY47919.1 1.58e-81 32_[10(2.76e-09)]_13_[3(5.02e-16)]_\ [7(4.67e-06)]_4_[14(1.54e-12)]_22_[8(7.06e-08)]_1_[11(1.16e-08)]_4_\ [15(4.21e-08)]_[17(6.18e-14)]_[6(3.91e-12)]_8_[5(6.15e-07)]_2_\ [2(2.28e-16)]_[1(1.60e-23)] XP_024982170.1 6.22e-55 20_[3(4.95e-09)]_[7(5.33e-07)]_38_\ [4(2.19e-12)]_[8(1.25e-08)]_1_[11(5.57e-10)]_35_[6(3.23e-06)]_3_\ [5(6.12e-10)]_2_[2(1.99e-16)]_[1(2.63e-22)] XP_027149457.1 5.44e-83 2_[3(1.78e-14)]_39_[4(1.80e-11)]_\ [8(2.80e-08)]_3_[11(1.43e-09)]_4_[15(1.43e-10)]_[17(4.13e-05)]_6_\ [6(2.70e-19)]_7_[5(1.40e-17)]_2_[2(5.56e-17)]_[1(1.19e-23)] PSS34997.1 5.50e-84 [10(1.26e-09)]_13_[3(2.20e-17)]_\ [7(8.48e-11)]_4_[14(1.93e-10)]_12_[4(1.48e-10)]_15_[11(6.90e-11)]_19_\ [17(3.85e-07)]_6_[6(1.06e-16)]_8_[5(5.89e-08)]_2_[2(1.39e-17)]_\ [1(2.31e-20)] XP_004137783.2 8.21e-93 91_[10(3.95e-14)]_13_[3(4.03e-15)]_\ [7(4.73e-05)]_4_[14(6.10e-13)]_12_[4(6.45e-12)]_[8(3.97e-11)]_1_\ [11(5.02e-07)]_4_[15(1.43e-10)]_20_[6(6.69e-15)]_8_[5(9.77e-14)]_2_\ [2(3.41e-15)]_[1(2.80e-23)] RWR86109.1 3.00e-58 [10(9.60e-10)]_2_[3(6.40e-16)]_\ [7(1.83e-07)]_38_[4(7.91e-13)]_1_[8(5.39e-06)]_91_[5(1.21e-07)]_2_\ [2(5.99e-16)]_[1(6.57e-24)] XP_028783417.1 8.62e-73 [10(1.70e-08)]_1_[18(1.19e-11)]_1_\ [3(5.57e-15)]_[7(1.57e-10)]_14_[4(1.48e-10)]_[8(3.57e-11)]_30_\ [6(1.31e-11)]_8_[5(5.93e-09)]_2_[2(3.00e-16)]_[1(7.82e-22)] XP_022039957.1 5.01e-38 49_[3(4.53e-08)]_1_[7(2.11e-05)]_3_\ [4(2.95e-09)]_33_[5(8.49e-07)]_2_[2(3.85e-15)]_5_[1(1.83e-23)] XP_022948410.1 5.30e-79 [10(5.28e-14)]_3_[3(4.03e-15)]_\ [7(7.42e-06)]_4_[14(8.90e-11)]_12_[4(1.63e-11)]_[8(9.11e-11)]_8_\ [15(2.32e-09)]_20_[6(2.89e-08)]_3_[5(2.29e-11)]_2_[2(2.64e-18)]_\ [1(2.63e-19)] XP_004514391.1 1.25e-115 2_[10(5.90e-09)]_1_[18(1.11e-14)]_1_\ [3(2.69e-13)]_[7(5.63e-06)]_4_[14(2.43e-10)]_12_[4(2.59e-17)]_\ [8(9.59e-12)]_6_[13(9.77e-29)]_1_[6(3.00e-12)]_8_[5(7.40e-16)]_2_\ [2(1.98e-18)]_[1(5.47e-22)] XP_028119329.1 8.07e-97 [10(6.03e-11)]_13_[3(4.85e-14)]_\ [7(8.48e-11)]_2_[14(6.87e-10)]_12_[4(1.76e-12)]_[8(4.41e-11)]_\ [15(1.36e-14)]_[17(1.60e-12)]_6_[6(1.91e-16)]_8_[5(5.05e-09)]_2_\ [2(2.17e-17)]_[1(6.93e-20)] TKS09656.1 4.68e-113 [10(3.24e-12)]_13_[3(6.40e-16)]_\ [7(4.33e-11)]_4_[14(6.10e-13)]_12_[4(9.30e-15)]_[8(2.08e-13)]_1_\ [11(4.28e-14)]_18_[17(6.18e-14)]_6_[6(1.02e-14)]_8_[5(2.80e-11)]_2_\ [2(1.34e-13)]_[1(8.85e-26)] XP_008803152.1 1.68e-53 75_[5(3.47e-05)]_12_[3(5.56e-13)]_2_\ [7(1.62e-07)]_35_[4(6.63e-10)]_22_[11(1.99e-09)]_38_[6(2.37e-11)]_8_\ [5(1.23e-09)]_2_[2(3.99e-12)]_5_[1(3.35e-26)] PWA88889.1 1.05e-29 15_[4(1.11e-08)]_54_[5(7.87e-08)]_3_\ [2(1.86e-13)]_[1(1.83e-23)] GAV76568.1 6.65e-98 [10(6.41e-09)]_13_[3(1.66e-18)]_\ [7(5.33e-07)]_4_[14(1.54e-12)]_12_[4(1.18e-15)]_[8(6.82e-12)]_1_\ [11(1.55e-09)]_4_[15(1.29e-09)]_29_[6(7.04e-14)]_7_[5(6.02e-12)]_2_\ [2(2.85e-13)]_[1(1.06e-25)] XP_027176296.1 3.65e-77 12_[3(2.95e-13)]_39_[4(9.79e-12)]_\ [8(9.53e-08)]_3_[11(6.42e-08)]_4_[15(3.78e-10)]_27_[6(3.63e-18)]_7_\ [5(4.52e-15)]_2_[2(3.41e-15)]_[1(4.15e-24)] XP_012832023.1 8.30e-56 12_[3(1.65e-10)]_[7(8.48e-11)]_5_\ [8(1.04e-06)]_18_[11(3.26e-09)]_5_[15(5.49e-13)]_15_[6(5.51e-07)]_13_\ [2(3.41e-15)]_[1(4.28e-21)] XP_015960799.1 4.60e-77 [10(7.38e-11)]_1_[18(2.28e-05)]_1_\ [3(7.17e-14)]_[7(4.76e-10)]_4_[14(2.13e-13)]_12_[4(2.02e-16)]_\ [8(1.87e-11)]_18_[5(6.73e-11)]_2_[2(6.24e-15)]_[1(2.45e-23)] XP_019162543.1 7.28e-81 1_[10(9.69e-06)]_13_[3(1.47e-16)]_\ [7(3.76e-07)]_17_[4(4.70e-10)]_16_[11(9.93e-09)]_4_[15(3.75e-17)]_27_\ [6(7.38e-17)]_8_[5(1.19e-15)]_2_[2(1.28e-15)]_[1(7.82e-22)] XP_012850185.1 6.01e-52 17_[3(1.17e-14)]_[7(2.67e-09)]_17_\ [4(7.91e-13)]_[8(1.55e-05)]_13_[15(1.11e-10)]_27_[6(6.24e-08)]_3_\ [2(7.80e-14)]_1_[1(1.01e-20)] XP_010937591.1 1.52e-53 21_[10(6.30e-08)]_13_[3(5.56e-13)]_\ 2_[7(1.03e-06)]_34_[4(8.17e-09)]_22_[11(2.74e-10)]_38_[6(1.24e-07)]_8_\ [5(6.12e-10)]_2_[2(5.54e-11)]_[1(1.14e-24)] XP_010037822.1 1.82e-67 [10(9.60e-10)]_11_[3(5.06e-11)]_\ [7(7.51e-08)]_4_[14(1.42e-10)]_12_[4(3.04e-15)]_[8(1.73e-08)]_60_\ [6(6.35e-11)]_7_[5(6.81e-08)]_2_[2(4.40e-12)]_[1(8.79e-22)] XP_020553487.1 2.12e-81 [10(2.17e-10)]_3_[3(2.88e-12)]_\ [7(2.97e-07)]_28_[4(5.59e-13)]_[8(4.47e-08)]_1_[11(2.17e-09)]_4_\ [15(1.82e-12)]_27_[6(3.82e-16)]_8_[5(1.19e-10)]_2_[2(1.13e-15)]_\ [1(4.29e-22)] XP_018841755.1 7.08e-92 [10(4.44e-11)]_13_[3(8.07e-16)]_\ [7(7.16e-12)]_4_[14(1.64e-14)]_12_[4(1.11e-13)]_11_[17(3.01e-10)]_4_\ [6(1.21e-11)]_8_[5(3.93e-12)]_3_[2(1.74e-16)]_[1(4.28e-21)] XP_022143715.1 6.66e-23 30_[3(1.43e-09)]_40_[8(2.57e-06)]_\ 31_[2(2.97e-12)]_2_[1(1.81e-19)] RID43060.1 3.23e-53 31_[3(3.73e-11)]_1_[7(7.44e-07)]_4_\ [20(2.52e-30)]_8_[15(1.13e-06)]_47_[2(2.29e-10)]_1_[1(7.82e-22)] XP_008448098.1 6.74e-24 47_[3(6.83e-11)]_[7(1.26e-05)]_53_\ [6(1.03e-06)]_17_[2(2.85e-13)]_[1(1.03e-18)]_4 XP_006398684.1 1.19e-52 31_[3(1.72e-11)]_1_[7(3.76e-07)]_2_\ [20(2.94e-29)]_12_[15(6.59e-07)]_51_[2(1.73e-09)]_1_[1(3.84e-21)] XP_018806280.1 8.36e-84 [10(7.18e-12)]_13_[3(8.57e-17)]_\ [7(1.27e-07)]_4_[14(8.98e-12)]_12_[4(4.80e-11)]_7_[11(4.72e-05)]_12_\ [17(6.38e-13)]_4_[6(2.55e-15)]_8_[5(6.70e-14)]_2_[2(1.98e-18)]_\ [1(1.13e-15)]_1 ADE76868.1 1.61e-20 27_[3(2.83e-06)]_89_[7(6.77e-06)]_\ 12_[11(7.09e-05)]_199_[2(6.48e-12)]_[1(2.75e-21)] XP_019459351.1 3.15e-100 2_[10(8.16e-11)]_1_[18(5.60e-13)]_1_\ [3(3.41e-12)]_[7(3.80e-08)]_4_[14(8.69e-14)]_12_[4(5.22e-12)]_\ [8(5.84e-10)]_6_[13(4.51e-20)]_1_[6(2.74e-13)]_8_[5(4.56e-14)]_2_\ [2(2.56e-14)]_[1(2.20e-21)] TEY72131.1 3.14e-44 63_[3(1.08e-07)]_[7(1.83e-07)]_41_\ [11(2.23e-12)]_4_[15(7.04e-05)]_29_[5(7.40e-16)]_3_[2(4.34e-15)]_4_\ [1(4.68e-20)] XP_021744044.1 5.13e-38 11_[3(1.36e-07)]_[7(4.21e-07)]_24_\ [4(1.77e-10)]_12_[11(4.70e-12)]_70_[2(1.48e-10)]_[1(1.59e-22)] XP_010678090.1 1.37e-35 28_[3(6.69e-05)]_[7(2.65e-07)]_24_\ [4(1.39e-08)]_12_[11(1.10e-10)]_58_[5(1.39e-07)]_2_[2(1.34e-13)]_\ [1(1.97e-21)] OAY41326.1 2.83e-79 5_[3(3.95e-17)]_[7(3.32e-08)]_9_\ [8(1.34e-11)]_1_[11(1.11e-05)]_4_[15(6.53e-10)]_1_[17(4.53e-21)]_2_\ [6(2.29e-15)]_8_[5(1.31e-12)]_18_[1(1.23e-27)] XP_021856950.1 1.91e-32 9_[3(2.42e-05)]_2_[7(2.06e-07)]_25_\ [4(1.10e-09)]_13_[11(3.28e-10)]_66_[2(1.76e-10)]_[1(9.47e-23)] XP_013448883.1 3.83e-79 2_[10(8.16e-11)]_1_[18(1.11e-14)]_1_\ [3(7.17e-14)]_[7(4.41e-08)]_4_[14(2.08e-10)]_12_[4(2.59e-17)]_\ [8(3.21e-11)]_16_[6(6.92e-05)]_1_[5(1.37e-15)]_2_[2(5.06e-11)]_2_\ [1(5.02e-19)] RAL39303.1 2.29e-56 14_[3(3.61e-14)]_[7(5.13e-06)]_19_\ [4(4.31e-10)]_7_[11(1.02e-06)]_4_[15(1.92e-13)]_43_[5(6.01e-15)]_2_\ [2(6.56e-13)]_1_[1(9.09e-21)]_1 PKI39361.1 4.82e-65 [10(1.34e-08)]_13_[3(5.09e-13)]_\ [7(8.48e-11)]_42_[4(2.11e-13)]_[8(1.88e-08)]_61_[6(4.66e-20)]_22_\ [2(6.64e-11)]_[1(4.78e-21)] XP_023544624.1 4.79e-29 33_[3(7.26e-13)]_[7(5.63e-06)]_60_\ [6(3.32e-10)]_17_[2(1.08e-13)]_[1(7.90e-16)]_3 XP_021741222.1 2.43e-33 11_[3(1.80e-07)]_[7(2.37e-06)]_22_\ [4(3.62e-10)]_12_[11(3.53e-11)]_71_[2(1.53e-07)]_[1(1.40e-22)] XP_020108001.1 9.09e-36 1_[10(9.04e-05)]_13_[3(2.13e-09)]_2_\ [7(2.61e-06)]_34_[4(1.55e-07)]_16_[11(3.54e-09)]_76_[2(1.81e-12)]_\ [1(1.59e-22)] RWW70318.1 3.54e-25 11_[4(7.01e-09)]_37_[6(5.05e-05)]_8_\ [5(3.64e-09)]_2_[2(4.18e-08)]_[1(8.85e-26)] KZV44349.1 1.15e-34 [10(1.25e-11)]_3_[3(2.93e-10)]_\ [7(2.65e-07)]_34_[8(1.75e-06)]_1_[11(8.33e-06)]_18_[6(1.69e-06)]_21_\ [1(6.59e-19)] XP_020268040.1 2.07e-30 12_[18(1.32e-05)]_1_[3(1.02e-07)]_3_\ [7(1.78e-05)]_29_[4(1.01e-09)]_29_[5(7.32e-08)]_[2(5.32e-09)]_\ [1(2.98e-22)] XP_020593816.1 7.17e-31 6_[11(8.23e-05)]_1_[3(3.15e-09)]_2_\ [7(6.95e-05)]_29_[4(8.48e-11)]_30_[15(2.87e-05)]_50_[2(1.92e-10)]_1_\ [1(7.34e-21)] XP_010543288.1 3.80e-38 1_[10(2.32e-09)]_13_[3(1.72e-11)]_\ [7(9.70e-06)]_24_[20(6.56e-20)]_74_[1(5.93e-21)] EFJ36024.1 3.09e-10 15_[13(2.71e-05)]_213_[6(9.83e-05)]_\ 247_[3(8.29e-05)]_98_[1(1.22e-16)] KFK24705.1 4.57e-44 12_[3(4.37e-12)]_1_[7(1.57e-06)]_4_\ [20(6.94e-29)]_69_[2(7.29e-09)]_[1(1.13e-16)] PNX96427.1 6.25e-85 1_[18(4.02e-13)]_1_[3(2.04e-13)]_\ [7(4.41e-08)]_4_[14(9.77e-12)]_12_[4(1.75e-15)]_[8(1.87e-11)]_6_\ [13(2.34e-27)]_23_[5(4.87e-12)]_2_[2(3.61e-08)]_1_[1(1.99e-19)] XP_010558336.1 8.64e-47 [10(4.59e-09)]_11_[3(4.75e-12)]_\ [7(1.06e-05)]_24_[20(4.31e-25)]_15_[15(1.34e-05)]_33_[2(1.30e-05)]_19_\ [2(2.21e-09)]_1_[1(4.11e-17)] XP_014752653.1 8.15e-114 34_[3(8.54e-11)]_2_[7(2.70e-05)]_7_\ [9(3.34e-55)]_12_[12(2.56e-49)]_20_[5(1.65e-08)]_12_[1(1.01e-20)] VAI07274.1 1.20e-104 46_[3(2.05e-10)]_2_[7(1.50e-05)]_7_\ [9(1.75e-50)]_8_[12(1.39e-45)]_20_[5(8.15e-11)]_7_[1(2.19e-19)] OAE24336.1 1.80e-10 535_[2(1.59e-09)]_3_[1(1.85e-17)] EEC74952.1 1.27e-95 48_[3(1.77e-10)]_2_[7(6.17e-06)]_7_\ [9(7.73e-47)]_9_[12(5.64e-45)]_28_[5(3.03e-08)]_12_[1(2.70e-18)] RLN19347.1 1.35e-117 45_[3(1.53e-10)]_2_[7(6.17e-06)]_7_\ [9(1.98e-58)]_12_[12(5.64e-51)]_27_[5(2.28e-10)]_11_[1(3.36e-22)] XP_021307618.1 1.06e-117 1_[16(1.79e-06)]_46_[3(5.89e-10)]_2_\ [7(9.37e-05)]_7_[9(2.29e-58)]_12_[12(1.29e-50)]_28_[5(1.08e-10)]_11_\ [1(4.28e-21)] OEL29447.1 3.83e-118 141_[3(7.93e-11)]_2_[7(6.17e-06)]_7_\ [9(4.01e-56)]_12_[12(6.39e-57)]_27_[5(5.60e-10)]_11_[1(7.82e-22)] XP_024401192.1 1.39e-08 366_[2(9.21e-09)]_[1(4.33e-15)] PSS23773.1 4.30e-52 2_[3(3.59e-15)]_[7(4.99e-09)]_4_\ [14(3.67e-08)]_13_[4(1.20e-08)]_8_[15(1.60e-07)]_[17(1.95e-12)]_6_\ [6(1.40e-07)]_4_[5(8.83e-09)]_13_[1(2.19e-19)] XP_018681881.1 2.72e-22 9_[4(2.02e-08)]_39_[6(7.05e-09)]_8_\ [5(1.10e-06)]_24_[1(3.83e-20)] XP_017215985.1 1.04e-35 [10(1.26e-09)]_13_[3(4.72e-17)]_\ [7(1.57e-06)]_36_[4(3.03e-10)]_[8(2.64e-07)]_99_[2(6.00e-06)]_1_\ [1(2.61e-16)] NP_001354359.1 2.11e-112 9_[16(9.30e-06)]_11_[3(2.05e-10)]_2_\ [7(9.37e-05)]_7_[9(8.10e-57)]_12_[12(4.02e-49)]_28_[5(9.56e-09)]_11_\ [1(5.32e-21)] EPS60070.1 1.70e-22 [10(4.14e-05)]_3_[3(2.01e-11)]_\ [7(3.18e-05)]_8_[12(7.62e-05)]_32_[5(3.39e-07)]_12_[1(8.63e-19)] -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (20) found. ******************************************************************************** CPU: ip-172-31-8-29 ********************************************************************************