"","level","gene","mutation","counts","freq","freq_s","group","dif","dif_s" "1","Low","ALK",1,13,2.55402750491159,-2.55402750491159,"DDX11",0,NA "2","High","ALK",1,15,2.94695481335953,2.94695481335953,"DDX11",2,2 "3","Low","ALK",1,15,2.94695481335953,-2.94695481335953,"DDX5",0,NA "4","High","ALK",1,13,2.55402750491159,2.55402750491159,"DDX5",-2,-2 "5","Low","ALK",1,11,2.16110019646365,-2.16110019646365,"DDX55",-2,NA "6","High","ALK",1,17,3.33988212180747,3.33988212180747,"DDX55",6,6 "7","Low","ALK",1,19,3.7328094302554,-3.7328094302554,"DDX56",2,NA "8","High","ALK",1,9,1.76817288801572,1.76817288801572,"DDX56",-10,-10 "9","Low","ALK",1,6,1.17878192534381,-1.17878192534381,NA,-3,NA "10","High","ALK",1,22,4.32220039292731,4.32220039292731,NA,16,16 "11","Low","ATM",1,15,2.94695481335953,-2.94695481335953,"DDX11",-7,NA "12","High","ATM",1,26,5.10805500982318,5.10805500982318,"DDX11",11,11 "13","Low","ATM",1,17,3.33988212180747,-3.33988212180747,"DDX5",-9,NA "14","High","ATM",1,24,4.71512770137525,4.71512770137525,"DDX5",7,7 "15","Low","ATM",1,15,2.94695481335953,-2.94695481335953,"DDX55",-9,NA "16","High","ATM",1,26,5.10805500982318,5.10805500982318,"DDX55",11,11 "17","Low","ATM",1,22,4.32220039292731,-4.32220039292731,"DDX56",-4,NA "18","High","ATM",1,19,3.7328094302554,3.7328094302554,"DDX56",-3,-3 "19","Low","ATM",1,20,3.92927308447937,-3.92927308447937,NA,1,NA "20","High","ATM",1,21,4.12573673870334,4.12573673870334,NA,1,1 "21","Low","BRAF",1,25,4.91159135559921,-4.91159135559921,"DDX11",4,NA "22","High","BRAF",1,16,3.1434184675835,3.1434184675835,"DDX11",-9,-9 "23","Low","BRAF",1,26,5.10805500982318,-5.10805500982318,"DDX5",10,NA "24","High","BRAF",1,15,2.94695481335953,2.94695481335953,"DDX5",-11,-11 "25","Low","BRAF",1,24,4.71512770137525,-4.71512770137525,"DDX55",9,NA "26","High","BRAF",1,17,3.33988212180747,3.33988212180747,"DDX55",-7,-7 "27","Low","BRAF",1,20,3.92927308447937,-3.92927308447937,"DDX56",3,NA "28","High","BRAF",1,21,4.12573673870334,4.12573673870334,"DDX56",1,1 "29","Low","BRAF",1,17,3.33988212180747,-3.33988212180747,NA,-4,NA "30","High","BRAF",1,24,4.71512770137525,4.71512770137525,NA,7,7 "31","Low","CDKN2A",1,8,1.57170923379175,-1.57170923379175,"DDX11",-16,NA "32","High","CDKN2A",1,12,2.35756385068762,2.35756385068762,"DDX11",4,4 "33","Low","CDKN2A",1,13,2.55402750491159,-2.55402750491159,"DDX5",1,NA "34","High","CDKN2A",1,7,1.37524557956778,1.37524557956778,"DDX5",-6,-6 "35","Low","CDKN2A",1,8,1.57170923379175,-1.57170923379175,"DDX55",1,NA "36","High","CDKN2A",1,12,2.35756385068762,2.35756385068762,"DDX55",4,4 "37","Low","CDKN2A",1,12,2.35756385068762,-2.35756385068762,"DDX56",0,NA "38","High","CDKN2A",1,8,1.57170923379175,1.57170923379175,"DDX56",-4,-4 "39","Low","CDKN2A",1,7,1.37524557956778,-1.37524557956778,NA,-1,NA "40","High","CDKN2A",1,13,2.55402750491159,2.55402750491159,NA,6,6 "41","Low","CTNNB1",1,6,1.17878192534381,-1.17878192534381,"DDX11",-7,NA "42","High","CTNNB1",1,12,2.35756385068762,2.35756385068762,"DDX11",6,6 "43","Low","CTNNB1",1,12,2.35756385068762,-2.35756385068762,"DDX5",0,NA "44","High","CTNNB1",1,6,1.17878192534381,1.17878192534381,"DDX5",-6,-6 "45","Low","CTNNB1",1,9,1.76817288801572,-1.76817288801572,"DDX55",3,NA "46","High","CTNNB1",1,9,1.76817288801572,1.76817288801572,"DDX55",0,0 "47","Low","CTNNB1",1,5,0.982318271119843,-0.982318271119843,"DDX56",-4,NA "48","High","CTNNB1",1,13,2.55402750491159,2.55402750491159,"DDX56",8,8 "49","Low","CTNNB1",1,9,1.76817288801572,-1.76817288801572,NA,-4,NA "50","High","CTNNB1",1,9,1.76817288801572,1.76817288801572,NA,0,0 "51","Low","EGFR",1,38,7.46561886051081,-7.46561886051081,"DDX11",29,NA "52","High","EGFR",1,29,5.69744597249509,5.69744597249509,"DDX11",-9,-9 "53","Low","EGFR",1,35,6.8762278978389,-6.8762278978389,"DDX5",6,NA "54","High","EGFR",1,32,6.28683693516699,6.28683693516699,"DDX5",-3,-3 "55","Low","EGFR",1,47,9.23379174852652,-9.23379174852652,"DDX55",15,NA "56","High","EGFR",1,20,3.92927308447937,3.92927308447937,"DDX55",-27,-27 "57","Low","EGFR",1,25,4.91159135559921,-4.91159135559921,"DDX56",5,NA "58","High","EGFR",1,42,8.25147347740668,8.25147347740668,"DDX56",17,17 "59","Low","EGFR",1,42,8.25147347740668,-8.25147347740668,NA,0,NA "60","High","EGFR",1,25,4.91159135559921,4.91159135559921,NA,-17,-17 "61","Low","ERBB4",1,17,3.33988212180747,-3.33988212180747,"DDX11",-8,NA "62","High","ERBB4",1,23,4.51866404715128,4.51866404715128,"DDX11",6,6 "63","Low","ERBB4",1,22,4.32220039292731,-4.32220039292731,"DDX5",-1,NA "64","High","ERBB4",1,18,3.53634577603143,3.53634577603143,"DDX5",-4,-4 "65","Low","ERBB4",1,20,3.92927308447937,-3.92927308447937,"DDX55",2,NA "66","High","ERBB4",1,20,3.92927308447937,3.92927308447937,"DDX55",0,0 "67","Low","ERBB4",1,21,4.12573673870334,-4.12573673870334,"DDX56",1,NA "68","High","ERBB4",1,19,3.7328094302554,3.7328094302554,"DDX56",-2,-2 "69","Low","ERBB4",1,13,2.55402750491159,-2.55402750491159,NA,-6,NA "70","High","ERBB4",1,27,5.30451866404715,5.30451866404715,NA,14,14 "71","Low","KRAS",1,60,11.7878192534381,-11.7878192534381,"DDX11",33,NA "72","High","KRAS",1,88,17.2888015717092,17.2888015717092,"DDX11",28,28 "73","Low","KRAS",1,64,12.573673870334,-12.573673870334,"DDX5",-24,NA "74","High","KRAS",1,84,16.5029469548134,16.5029469548134,"DDX5",20,20 "75","Low","KRAS",1,69,13.5559921414538,-13.5559921414538,"DDX55",-15,NA "76","High","KRAS",1,79,15.5206286836935,15.5206286836935,"DDX55",10,10 "77","Low","KRAS",1,82,16.1100196463654,-16.1100196463654,"DDX56",3,NA "78","High","KRAS",1,66,12.9666011787819,12.9666011787819,"DDX56",-16,-16 "79","Low","KRAS",1,88,17.2888015717092,-17.2888015717092,NA,22,NA "80","High","KRAS",1,60,11.7878192534381,11.7878192534381,NA,-28,-28 "81","Low","MAP2",1,17,3.33988212180747,-3.33988212180747,"DDX11",-43,NA "82","High","MAP2",1,26,5.10805500982318,5.10805500982318,"DDX11",9,9 "83","Low","MAP2",1,24,4.71512770137525,-4.71512770137525,"DDX5",-2,NA "84","High","MAP2",1,19,3.7328094302554,3.7328094302554,"DDX5",-5,-5 "85","Low","MAP2",1,15,2.94695481335953,-2.94695481335953,"DDX55",-4,NA "86","High","MAP2",1,28,5.50098231827112,5.50098231827112,"DDX55",13,13 "87","Low","MAP2",1,27,5.30451866404715,-5.30451866404715,"DDX56",-1,NA "88","High","MAP2",1,16,3.1434184675835,3.1434184675835,"DDX56",-11,-11 "89","Low","MAP2",1,14,2.75049115913556,-2.75049115913556,NA,-2,NA "90","High","MAP2",1,29,5.69744597249509,5.69744597249509,NA,15,15 "91","Low","MET",1,9,1.76817288801572,-1.76817288801572,"DDX11",-20,NA "92","High","MET",1,11,2.16110019646365,2.16110019646365,"DDX11",2,2 "93","Low","MET",1,9,1.76817288801572,-1.76817288801572,"DDX5",-2,NA "94","High","MET",1,11,2.16110019646365,2.16110019646365,"DDX5",2,2 "95","Low","MET",1,15,2.94695481335953,-2.94695481335953,"DDX55",4,NA "96","High","MET",1,5,0.982318271119843,0.982318271119843,"DDX55",-10,-10 "97","Low","MET",1,4,0.785854616895874,-0.785854616895874,"DDX56",-1,NA "98","High","MET",1,16,3.1434184675835,3.1434184675835,"DDX56",12,12 "99","Low","MET",1,11,2.16110019646365,-2.16110019646365,NA,-5,NA "100","High","MET",1,9,1.76817288801572,1.76817288801572,NA,-2,-2 "101","Low","MUC16",1,102,20.0392927308448,-20.0392927308448,"DDX11",93,NA "102","High","MUC16",1,110,21.6110019646365,21.6110019646365,"DDX11",8,8 "103","Low","MUC16",1,113,22.2003929273084,-22.2003929273084,"DDX5",3,NA "104","High","MUC16",1,99,19.4499017681729,19.4499017681729,"DDX5",-14,-14 "105","Low","MUC16",1,96,18.860510805501,-18.860510805501,"DDX55",-3,NA "106","High","MUC16",1,116,22.7897838899804,22.7897838899804,"DDX55",20,20 "107","Low","MUC16",1,101,19.8428290766208,-19.8428290766208,"DDX56",-15,NA "108","High","MUC16",1,111,21.8074656188605,21.8074656188605,"DDX56",10,10 "109","Low","MUC16",1,89,17.4852652259332,-17.4852652259332,NA,-22,NA "110","High","MUC16",1,123,24.1650294695481,24.1650294695481,NA,34,34 "111","Low","NF1",1,29,5.69744597249509,-5.69744597249509,"DDX11",-94,NA "112","High","NF1",1,29,5.69744597249509,5.69744597249509,"DDX11",0,0 "113","Low","NF1",1,33,6.48330058939096,-6.48330058939096,"DDX5",4,NA "114","High","NF1",1,25,4.91159135559921,4.91159135559921,"DDX5",-8,-8 "115","Low","NF1",1,27,5.30451866404715,-5.30451866404715,"DDX55",2,NA "116","High","NF1",1,31,6.09037328094303,6.09037328094303,"DDX55",4,4 "117","Low","NF1",1,28,5.50098231827112,-5.50098231827112,"DDX56",-3,NA "118","High","NF1",1,30,5.89390962671906,5.89390962671906,"DDX56",2,2 "119","Low","NF1",1,27,5.30451866404715,-5.30451866404715,NA,-3,NA "120","High","NF1",1,31,6.09037328094303,6.09037328094303,NA,4,4 "121","Low","NTRK3",1,12,2.35756385068762,-2.35756385068762,"DDX11",-19,NA "122","High","NTRK3",1,31,6.09037328094303,6.09037328094303,"DDX11",19,19 "123","Low","NTRK3",1,26,5.10805500982318,-5.10805500982318,"DDX5",-5,NA "124","High","NTRK3",1,17,3.33988212180747,3.33988212180747,"DDX5",-9,-9 "125","Low","NTRK3",1,12,2.35756385068762,-2.35756385068762,"DDX55",-5,NA "126","High","NTRK3",1,31,6.09037328094303,6.09037328094303,"DDX55",19,19 "127","Low","NTRK3",1,20,3.92927308447937,-3.92927308447937,"DDX56",-11,NA "128","High","NTRK3",1,23,4.51866404715128,4.51866404715128,"DDX56",3,3 "129","Low","NTRK3",1,11,2.16110019646365,-2.16110019646365,NA,-12,NA "130","High","NTRK3",1,32,6.28683693516699,6.28683693516699,NA,21,21 "131","Low","PIK3CA",1,15,2.94695481335953,-2.94695481335953,"DDX11",-17,NA "132","High","PIK3CA",1,12,2.35756385068762,2.35756385068762,"DDX11",-3,-3 "133","Low","PIK3CA",1,14,2.75049115913556,-2.75049115913556,"DDX5",2,NA "134","High","PIK3CA",1,13,2.55402750491159,2.55402750491159,"DDX5",-1,-1 "135","Low","PIK3CA",1,15,2.94695481335953,-2.94695481335953,"DDX55",2,NA "136","High","PIK3CA",1,12,2.35756385068762,2.35756385068762,"DDX55",-3,-3 "137","Low","PIK3CA",1,15,2.94695481335953,-2.94695481335953,"DDX56",3,NA "138","High","PIK3CA",1,12,2.35756385068762,2.35756385068762,"DDX56",-3,-3 "139","Low","PIK3CA",1,7,1.37524557956778,-1.37524557956778,NA,-5,NA "140","High","PIK3CA",1,20,3.92927308447937,3.92927308447937,NA,13,13 "141","Low","RB1",1,8,1.57170923379175,-1.57170923379175,"DDX11",-12,NA "142","High","RB1",1,19,3.7328094302554,3.7328094302554,"DDX11",11,11 "143","Low","RB1",1,13,2.55402750491159,-2.55402750491159,"DDX5",-6,NA "144","High","RB1",1,14,2.75049115913556,2.75049115913556,"DDX5",1,1 "145","Low","RB1",1,10,1.96463654223969,-1.96463654223969,"DDX55",-4,NA "146","High","RB1",1,17,3.33988212180747,3.33988212180747,"DDX55",7,7 "147","Low","RB1",1,9,1.76817288801572,-1.76817288801572,"DDX56",-8,NA "148","High","RB1",1,18,3.53634577603143,3.53634577603143,"DDX56",9,9 "149","Low","RB1",1,11,2.16110019646365,-2.16110019646365,NA,-7,NA "150","High","RB1",1,16,3.1434184675835,3.1434184675835,NA,5,5 "151","Low","RET",1,7,1.37524557956778,-1.37524557956778,"DDX11",-9,NA "152","High","RET",1,11,2.16110019646365,2.16110019646365,"DDX11",4,4 "153","Low","RET",1,11,2.16110019646365,-2.16110019646365,"DDX5",0,NA "154","High","RET",1,7,1.37524557956778,1.37524557956778,"DDX5",-4,-4 "155","Low","RET",1,7,1.37524557956778,-1.37524557956778,"DDX55",0,NA "156","High","RET",1,11,2.16110019646365,2.16110019646365,"DDX55",4,4 "157","Low","RET",1,5,0.982318271119843,-0.982318271119843,"DDX56",-6,NA "158","High","RET",1,13,2.55402750491159,2.55402750491159,"DDX56",8,8 "159","Low","RET",1,4,0.785854616895874,-0.785854616895874,NA,-9,NA "160","High","RET",1,14,2.75049115913556,2.75049115913556,NA,10,10 "161","Low","ROS1",1,6,1.17878192534381,-1.17878192534381,"DDX11",-8,NA "162","High","ROS1",1,15,2.94695481335953,2.94695481335953,"DDX11",9,9 "163","Low","ROS1",1,13,2.55402750491159,-2.55402750491159,"DDX5",-2,NA "164","High","ROS1",1,8,1.57170923379175,1.57170923379175,"DDX5",-5,-5 "165","Low","ROS1",1,9,1.76817288801572,-1.76817288801572,"DDX55",1,NA "166","High","ROS1",1,12,2.35756385068762,2.35756385068762,"DDX55",3,3 "167","Low","ROS1",1,13,2.55402750491159,-2.55402750491159,"DDX56",1,NA "168","High","ROS1",1,8,1.57170923379175,1.57170923379175,"DDX56",-5,-5 "169","Low","ROS1",1,7,1.37524557956778,-1.37524557956778,NA,-1,NA "170","High","ROS1",1,14,2.75049115913556,2.75049115913556,NA,7,7 "171","Low","SMARCA4",1,20,3.92927308447937,-3.92927308447937,"DDX11",6,NA "172","High","SMARCA4",1,22,4.32220039292731,4.32220039292731,"DDX11",2,2 "173","Low","SMARCA4",1,31,6.09037328094303,-6.09037328094303,"DDX5",9,NA "174","High","SMARCA4",1,11,2.16110019646365,2.16110019646365,"DDX5",-20,-20 "175","Low","SMARCA4",1,7,1.37524557956778,-1.37524557956778,"DDX55",-4,NA "176","High","SMARCA4",1,35,6.8762278978389,6.8762278978389,"DDX55",28,28 "177","Low","SMARCA4",1,16,3.1434184675835,-3.1434184675835,"DDX56",-19,NA "178","High","SMARCA4",1,26,5.10805500982318,5.10805500982318,"DDX56",10,10 "179","Low","SMARCA4",1,11,2.16110019646365,-2.16110019646365,NA,-15,NA "180","High","SMARCA4",1,31,6.09037328094303,6.09037328094303,NA,20,20 "181","Low","STK11",1,25,4.91159135559921,-4.91159135559921,"DDX11",-6,NA "182","High","STK11",1,44,8.64440078585462,8.64440078585462,"DDX11",19,19 "183","Low","STK11",1,37,7.26915520628684,-7.26915520628684,"DDX5",-7,NA "184","High","STK11",1,32,6.28683693516699,6.28683693516699,"DDX5",-5,-5 "185","Low","STK11",1,31,6.09037328094303,-6.09037328094303,"DDX55",-1,NA "186","High","STK11",1,38,7.46561886051081,7.46561886051081,"DDX55",7,7 "187","Low","STK11",1,34,6.67976424361493,-6.67976424361493,"DDX56",-4,NA "188","High","STK11",1,35,6.8762278978389,6.8762278978389,"DDX56",1,1 "189","Low","STK11",1,38,7.46561886051081,-7.46561886051081,NA,3,NA "190","High","STK11",1,31,6.09037328094303,6.09037328094303,NA,-7,-7 "191","Low","TP53",1,112,22.0039292730845,-22.0039292730845,"DDX11",81,NA "192","High","TP53",1,145,28.4872298624754,28.4872298624754,"DDX11",33,33 "193","Low","TP53",1,148,29.0766208251473,-29.0766208251473,"DDX5",3,NA "194","High","TP53",1,109,21.4145383104126,21.4145383104126,"DDX5",-39,-39 "195","Low","TP53",1,109,21.4145383104126,-21.4145383104126,"DDX55",0,NA "196","High","TP53",1,148,29.0766208251473,29.0766208251473,"DDX55",39,39 "197","Low","TP53",1,107,21.0216110019646,-21.0216110019646,"DDX56",-41,NA "198","High","TP53",1,150,29.4695481335953,29.4695481335953,"DDX56",43,43 "199","Low","TP53",1,103,20.2357563850688,-20.2357563850688,NA,-47,NA "200","High","TP53",1,154,30.2554027504912,30.2554027504912,NA,51,51