Pathway_ID Pathway name Single.p.M.12 Single.p.M.9 Single.p.M.6 Single.p.M.3 Single.p.M.0 Fisher's.Method.lowest.pvalue FisherMethod.p FisherMethod.padjust Activation of NF-kappaB in B cells Activation of NFKB in B cells 0.30938 0.17365 0.9022 0.001996 0.001996 M-3_M-0 5,35E+08 0.000250350055577756 Adherens_junction Adherens junction 0.86627 0.4012 0.84232 0.017964 0.88822 M-9_M-3 0.0427577603854548 0.0329646252643397 Adipocytokine_signaling_pathway Adipocytokine signaling 0.027944 0.033932 0.38922 0.66068 0.74251 M-12_M-9 0.00754853897063679 0.0220523618220449 Akt signaling pathway AKT signaling 0.065868 0.023952 0.81637 0.6008 0.92216 M-12_M-9 0.0117564932615193 0.0453028106831704 Amino_sugar_and_nucleotide_sugar_metabolism Amino and nucleotide sugar metabol 0.3493 0.02994 0.5988 0.001996 0.47505 M-9_M-3 0.000640938733305507 0.0031693557632859 AMPK_signaling_pathway AMPK signaling 0.023952 0.38124 0.20758 0.21557 0.50299 M-12_M-6 0.0313429228750984 0.03381970769127 Antigen processing-Cross presentation Antigen processing-Cross presentation 0.6507 0.39122 0.6008 0.001996 0.015968 M-3_M-0 0.000361869086751287 0.00114732192863429 Apoptosis Apoptosis 0.27146 0.00998 0.63473 0.001996 0.18164 M-9_M-3 0.000235530689114416 0.000937481789361372 Ascorbate_and_aldarate_metabolism Ascorbate metabol 0.00998 0.88822 0.1996 0.49701 0.021956 M-12_M-0 0.00206540865793536 0.0157527262168881 beta-catenin independent WNT signaling beta-catenin independent WNT signaling 0.42315 0.10379 NA 0.001996 0.017964 M-9_M-3_M-0 0.000341052678561216 0.000950829442519892 Biosynthesis_of_unsaturated_fatty_acids Unsaturated fatty acids 0.49701 0.005988 0.49102 0.13972 0.24551 M-9_M-3 0.00676519247479579 0.0141797838548445 Cell_adhesion_molecules_(CAMs) Cell adhesion molecules 0.005988 0.21158 0.50299 0.87226 0.95609 M-12_M-9 0.00971889464984688 0.0275213168448157 Cell_cycle Cell cycle 0.55888 0.48902 0.94611 0.001996 0.005988 M-3_M-0 0.00014742382584354 0.00123599616318602 Ceramide signaling pathway Ceramide signaling 0.053892 0.035928 0.5489 0.22954 0.55888 M-12_M-9 0.0140318940989158 0.0396408269687172 Cxcr4 signaling pathway CXCR4 signaling 0.36727 0.005988 0.057884 0.1477 0.38124 M-9_M-6_M-3 0.00305557436939707 0.033547175298518 Cysteine_and_methionine_metabolism Cysteine & methionine metabol 0.051896 0.56088 0.42116 0.043912 0.82435 M-12_M-3 0.0161436091325939 0.0229635839917782 Detoxification of Reactive Oxygen Species ROS detoxification 0.1477 0.13174 0.22954 0.001996 0.11976 M-12_M-9_M-3_M-0 0.00184733556003824 0.00404095269223191 DNA_REPAIR DNA repair 0.017964 0.005988 0.55289 0.011976 0.49102 M-12_M-9_M-3 0.00013723529405163 0.000374387123448012 Fatty_acid_metabolism Fatty acid metabol 0.71856 0.031936 0.18164 0.093812 0.0998 M-9_M-6_M-3_M-0 0.0117804729501956 0.0210968470151291 FoxO_signaling_pathway FoxO signaling 0.3014 0.47705 0.10579 0.037924 0.62076 M-6_M-3 0.0261519726303395 0.0392128678165251 Galactose_metabolism Galactose metabol 0.70858 0.11178 0.027944 0.10379 0.023952 M-9_M-6_M-3_M-0 0.00274461377735358 0.00767024841207774 Gap_junction Gap junction 0.22156 0.74251 0.005988 0.74052 0.54092 M-12_M-6 0.010116176408666 0.0423467628559482 Glycolysis_/_Gluconeogenesis Glycolysis / Gluconeogenesis 0.065868 0.031936 0.13373 0.003992 0.29541 M-12_M-9_M-6_M-3 0.000603101533577122 0.00378991930233265 GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN_VIA_MHC_CLASS_I MHC class I antigen presentation 0.34531 0.26347 0.79042 0.001996 0.021956 M-3_M-0 0.000483614021922651 0.00556595368826156 GO_C_C_CHEMOKINE_RECEPTOR_ACTIVITY Chemokine receptor activity 0.97605 0.033932 0.045908 0.78842 0.1497 M-9_M-6_M-0 0.0103396021600861 0.0378839026852489 GO_FC_EPSILON_RECEPTOR_SIGNALING_PATHWAY FCepsilon signaling pathway 0.31138 0.02994 0.77645 0.001996 0.0998 M-9_M-3_M-0 0.000509255911526729 0.00396295817649745 GO_INNATE_IMMUNE_RESPONSE_ACTIVATING_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY Activation of cell surface receptors 0.7525 0.10579 0.48104 0.001996 0.011976 M-9_M-3_M-0 0.000245130461742349 0.00282088645384685 GO_INSULIN_RECEPTOR_BINDING Insulin receptor binding 0.5489 0.49102 0.51896 0.64271 0.011976 M-9_M-0 0.0360831869038856 0.0469407630001978 GO_NIK_NF_KAPPAB_SIGNALING NIK/NFKB signaling 0.37126 0.071856 0.97605 0.001996 0.001996 M-9_M-3_M-0 3,71E+09 0.00155917588016208 GO_POSITIVE_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY WNT signaling 0.53094 0.34132 0.93812 0.003992 0.001996 M-3_M-0 0.000101513309518686 0.00282401228662157 GO_POSITIVE_REGULATION_OF_NATURAL_KILLER_CELL_MEDIATED_IMMUNITY Pos. regulation Natural Killer immunity 0.61477 0.02994 0.9521 0.1477 0.85828 M-9_M-3 0.0283951317734982 0.0338132424333331 GO_POSITIVE_REGULATION_OF_T_CELL_MEDIATED_CYTOTOXICITY T-cell cytotoxicity 0.36327 0.021956 0.37924 0.18363 0.76248 M-9_M-3 0.0262611913301816 0.0323183392610831 GO_REGULATION_OF_CALCIUM_MEDIATED_SIGNALING Regulation calcium signaling 0.007984 0.24351 0.48104 0.03992 0.32934 M-12_M-3 0.00288480799936519 0.0112904178265653 GO_REGULATION_OF_CYTOKINE_SECRETION_INVOLVED_IN_IMMUNE_RESPONSE Regulation of cytokine secretion 0.023952 0.07984 0.4491 0.97405 0.98004 M-12_M-9 0.013882416767284 0.0462785301468853 Inhibition of matrix metalloproteinases Inhibition of matrix metalloproteinases 0.047904 0.91617 0.20359 0.005988 0.45908 M-12_M-3 0.00262654977399934 0.0390142180704374 Inositol_phosphate_metabolism Inositol phosphate metabol 0.44711 0.003992 0.075848 0.3992 0.79042 M-9_M-6 0.00275609845061742 0.0158113104553521 Insulin_resistance Insuline resintance 0.44711 0.037924 0.27345 0.075848 0.25948 M-9_M-3 0.0197071854824241 0.0220299131922068 Insulin_signaling_pathway Insulin signaling 0.015968 0.39321 0.10978 0.05988 0.18563 M-12_M-6_M-3 0.00547214089613113 0.0174597325697265 Interleukin-7 signaling Interleukin-7 signaling 0.73253 0.42315 0.21956 0.96806 0.007984 M-6_M-0 0.0128780767793114 0.0433188156353635 Leukocyte_transendothelial_migration Leukocyte transendothelial migration 0.47904 0.07984 0.65669 0.091816 0.7485 M-9_M-3 0.043365563196927 0.0329646252643397 mTOR signalling mTOR signalling 0.017964 0.1517 0.61477 0.013972 0.091816 M-12_M-9_M-3_M-0 0.00147888840652854 0.00339152519317836 Nf-kb signaling pathway NFKB signaling 0.051896 0.057884 0.53293 0.70659 0.85828 M-12_M-9 0.0204503612425236 0.0485288142896677 Oxidative_phosphorylation Oxidative phosphorylation 0.047904 0.017964 0.76048 0.001996 0.031936 M-12_M-9_M-3_M-0 5,14E+08 0.000861222277392847 p53_signaling_pathway p53 signaling 0.45309 0.053892 0.72056 0.047904 0.64271 M-9_M-3 0.0179664999051321 0.0207766210170247 Phosphatidylinositol_signaling_system Phosphatidylinositol signaling 0.19361 0.003992 0.067864 0.23353 0.97006 M-9_M-6 0.00249611530450911 0.0110722923568333 Phospholipase c signaling pathway Phospholipase c signaling 0.29341 0.043912 0.15968 0.021956 0.40719 M-9_M-6_M-3 0.00743792773518037 0.033547175298518 PKA activation in glucagon signalling PKA activation in glucagon signalling 0.1018 0.83633 0.047904 0.41517 0.42715 M-12_M-6 0.0308363838234641 0.0487512490229907 PPARA activates gene expression PPARalpha control of gene expression 0.001996 0.1018 0.46507 0.00998 0.54092 M-12_M-9_M-3 0.000202837665847388 0.00196312747676904 Protein_processing_in_endoplasmic_reticulum Protein processin in ER 0.093812 0.003992 0.99601 0.001996 0.74251 M-12_M-9_M-3 8,57E+09 0.00138568975296931 Pyruvate_metabolism Pyruvate metabol 0.011976 0.11377 0.59681 0.017964 0.6487 M-12_M-9_M-3 0.00166405276336257 0.00465045325178771 Ras signaling pathway RAS signaling pathway 0.1018 0.005988 0.54092 0.52295 0.69661 M-12_M-9 0.0051221306258038 0.0390142180704374 RNA_transport RNA transport 0.13174 0.001996 0.99601 0.003992 0.12575 M-9_M-3 0.000101513309518686 0.00103697168593798 Spliceosome Spliceosome 0.015968 0.035928 0.85429 0.001996 0.001996 M-12_M-9_M-3_M-0 3,50E+08 0.00011739765377919 Tgf beta signaling pathway TGFB signaling 0.23752 0.037924 0.83433 0.013972 0.13373 M-9_M-3_M-0 0.00398247314093081 0.0260737895279162 TGF-beta_signaling_pathway TGF-beta signaling 0.29741 0.26347 0.9022 0.021956 0.6507 M-9_M-3 0.0355908348866637 0.0284183148647059 The citric acid (TCA) cycle and respiratory electron transport Citrate cycle (TCA cycle) 0.10778 0.001996 0.9521 0.001996 0.01996 M-12_M-9_M-3_M-0 1,08E+09 0.000255958581065433 Tnf/stress related signaling Tnf/stress related signaling 0.12176 0.021956 0.43912 0.40319 0.73852 M-12_M-9 0.0185114804008527 0.0467685576872899 Vitamin_B6_metabolism Vitamin B6 metabol 0.035928 0.76846 0.75449 0.045908 0.92216 M-12_M-3 0.0122175613540706 0.0204863208110574 Vitamin_digestion_and_absorption Vitamin digestion & absorption 0.061876 0.16367 0.27944 0.13174 0.25349 M-12_M-9_M-3 0.0393951943484373 0.0281096103665164