Feature ID Type Contig Start Stop Frame Strand Length (bp) Function Subsystem NCBI GI locus fig|83332.1.pbs.3 PBS NC_000962 2396081 2396096 2 + 16 NrdR_Proteobacteria - none - fig|83332.1.pbs.4 PBS NC_000962 4265613 4265628 3 + 16 NrdR_Proteobacteria - none - fig|83332.1.peg.1 CDS NC_000962 1 1524 1 + 1524 Chromosomal replication initiator protein DnaA DNA replication cluster 1 gi|15607143 fig|83332.1.peg.2 CDS NC_000962 2052 3260 3 + 1209 DNA polymerase III beta subunit (EC 2.7.7.7) DNA replication cluster 1 gi|15607144 fig|83332.1.peg.3 CDS NC_000962 3280 4437 1 + 1158 DNA recombination and repair protein RecF DNA repair, bacterial RecFOR pathway;
DNA replication cluster 1 gi|15607145 fig|83332.1.peg.4 CDS NC_000962 4434 4997 3 + 564 Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives DNA replication cluster 1 gi|15607146 fig|83332.1.peg.5 CDS NC_000962 5123 7267 2 + 2145 DNA gyrase subunit B (EC 5.99.1.3) DNA gyrase subunits;
DNA replication cluster 1;
DNA topoisomerases, Type II, ATP-dependent;
Resistance to fluoroquinolones gi|15607147 fig|83332.1.peg.6 CDS NC_000962 7302 9818 3 + 2517 DNA gyrase subunit A (EC 5.99.1.3) DNA gyrase subunits;
DNA replication cluster 1;
DNA topoisomerases, Type II, ATP-dependent;
Resistance to fluoroquinolones gi|15607148 fig|83332.1.peg.7 CDS NC_000962 9914 10828 2 + 915 FIG187021: hypothetical protein DNA replication cluster 1 gi|15607149 fig|83332.1.peg.8 CDS NC_000962 12311 11874 -2 - 438 FIG024317: hypothetical protein Peptidyl-prolyl cis-trans isomerase containing cluster gi|15607150 fig|83332.1.peg.9 CDS NC_000962 12468 13016 3 + 549 Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) Peptidyl-prolyl cis-trans isomerase containing cluster gi|15607151 fig|83332.1.peg.10 CDS NC_000962 13558 13133 -1 - 426 FIG020554: membrane protein Peptidyl-prolyl cis-trans isomerase containing cluster gi|15607152 fig|83332.1.peg.11 CDS NC_000962 13995 13714 -3 - 282 FIG018426: putative septation inhibitor protein - none - gi|15607153 fig|83332.1.peg.12 CDS NC_000962 14089 14877 1 + 789 FIG215594: Membrane spanning protein - none - gi|15607154 fig|83332.1.peg.13 CDS NC_000962 14914 15612 1 + 699 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) # TrpAb@PabAb Chorismate: Intermediate for synthesis of Tryptophan, PAPA antibiotics, PABA, 3-hydroxyanthranilate and more.;
Chorismate: Intermediate for synthesis of Tryptophan, PAPA antibiotics, PABA, 3-hydroxyanthranilate and more.;
Folate Biosynthesis;
Tryptophan synthesis;
Tryptophan synthesis gi|15607155 fig|83332.1.peg.14 CDS NC_000962 17470 15590 -1 - 1881 Serine/threonine-protein kinase PknB (EC 2.7.11.1) - none - gi|15607156 fig|83332.1.peg.15 CDS NC_000962 18762 17467 -3 - 1296 Serine/threonine-protein kinase PknA (EC 2.7.11.1) - none - gi|15607157 fig|83332.1.peg.16 CDS NC_000962 20234 18759 -2 - 1476 Cell division protein FtsI [Peptidoglycan synthetase] (EC 2.4.1.129) 16S rRNA modification within P site of ribosome;
Bacterial Cell Division;
Bacterial Cytoskeleton;
CBSS-83331.1.peg.3039;
Peptidoglycan Biosynthesis gi|15607158 fig|83332.1.peg.17 CDS NC_000962 21640 20231 -1 - 1410 Cell division protein FtsW Bacterial Cell Division;
Bacterial Cytoskeleton gi|15607159 fig|83332.1.peg.18 CDS NC_000962 23181 21637 -3 - 1545 Serine/threonine phosphatase PPP (EC 3.1.3.16) - none - gi|15607160 fig|83332.1.peg.19 CDS NC_000962 23737 23270 -1 - 468 FHA-domain-containing proteins - none - gi|15607161 fig|83332.1.peg.20 CDS NC_000962 25444 23861 -1 - 1584 hypothetical protein Rv0020c - none - gi|15607162 fig|83332.1.peg.21 CDS NC_000962 26881 25913 -1 - 969 Nitronate monooxygenase - none - gi|15607163 fig|83332.1.peg.22 CDS NC_000962 27442 27023 -1 - 420 WhiB family transcriptional regulator - none - gi|15607164 fig|83332.1.peg.23 CDS NC_000962 27595 28365 1 + 771 hypothetical protein Rv0023 - none - gi|15607165 fig|83332.1.peg.24 CDS NC_000962 28362 29207 3 + 846 Hypothetical secreted protein - none - gi|15607166 fig|83332.1.peg.25 CDS NC_000962 29245 29607 1 + 363 hypothetical protein - none - gi|15607167 fig|83332.1.peg.26 CDS NC_000962 29722 31068 1 + 1347 hypothetical protein - none - gi|15607168 fig|83332.1.peg.27 CDS NC_000962 31189 31506 1 + 318 hypothetical protein - none - gi|15607169 fig|83332.1.peg.28 CDS NC_000962 31514 31819 2 + 306 hypothetical protein - none - gi|15607170 fig|83332.1.peg.29 CDS NC_000962 32057 33154 2 + 1098 Vegetative cell wall protein gp1 precursor - none - gi|15607171 fig|83332.1.peg.30 CDS NC_000962 33224 33553 2 + 330 hypothetical protein - none - gi|15607172 fig|83332.1.peg.31 CDS NC_000962 33582 33794 3 + 213 hypothetical protein Rv0031 - none - gi|15607173 fig|83332.1.peg.32 CDS NC_000962 34295 36610 2 + 2316 Acetyltransferase (GNAT) domain / Aminotransferase class II, serine palmitoyltransferase like (EC 2.3.1.50) - none - gi|15607174 fig|83332.1.peg.33 CDS NC_000962 36607 36870 1 + 264 Phosphopantetheine-binding acyl carrier protein - none - gi|15607175 fig|83332.1.peg.34 CDS NC_000962 36867 37262 3 + 396 hypothetical protein Rv0034 - none - gi|15607176 fig|83332.1.peg.35 CDS NC_000962 37259 38947 2 + 1689 FIG022758: Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) - none - gi|15607177 fig|83332.1.peg.36 CDS NC_000962 39829 39056 -1 - 774 hypothetical protein - none - gi|15607178 fig|83332.1.peg.37 CDS NC_000962 41202 39877 -3 - 1326 hypothetical protein Rv0037c - none - gi|15607179 fig|83332.1.peg.38 CDS NC_000962 41304 41912 3 + 609 UPF0301 protein YqgE - none - gi|15607180 fig|83332.1.peg.39 CDS NC_000962 42351 42004 -3 - 348 hypothetical protein Rv0039c - none - gi|15607181 fig|83332.1.peg.40 CDS NC_000962 43363 42434 -1 - 930 hypothetical protein Rv0040c - none - gi|15607182 fig|83332.1.peg.41 CDS NC_000962 43560 46469 3 + 2910 Leucyl-tRNA synthetase (EC 6.1.1.4) tRNA aminoacylation, Leu gi|15607183 fig|83332.1.peg.42 CDS NC_000962 47205 46579 -3 - 627 Transcriptional regulator, MarR family - none - gi|15607184 fig|83332.1.peg.43 CDS NC_000962 48098 47364 -2 - 735 Transcriptional regulator, GntR family - none - gi|15607185 fig|83332.1.peg.44 CDS NC_000962 49025 48231 -2 - 795 hypothetical protein Rv0044c - none - gi|15607186 fig|83332.1.peg.45 CDS NC_000962 49937 49041 -2 - 897 hypothetical protein Rv0045c - none - gi|15607187 fig|83332.1.peg.46 CDS NC_000962 51122 50019 -2 - 1104 Inositol-1-phosphate synthase (EC 5.5.1.4) - none - gi|15607188 fig|83332.1.peg.47 CDS NC_000962 51725 51183 -2 - 543 Transcriptional regulator, PadR family CBSS-1352.1.peg.856 gi|15607189 fig|83332.1.peg.48 CDS NC_000962 52695 51826 -3 - 870 hypothetical protein Rv0048c - none - gi|15607190 fig|83332.1.peg.49 CDS NC_000962 52829 53242 2 + 414 hypothetical protein - none - gi|15607191 fig|83332.1.peg.50 CDS NC_000962 53661 55697 3 + 2037 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) Peptidoglycan Biosynthesis;
WhiB and WhiB-type regulatory proteins gi|15607192 fig|83332.1.peg.51 CDS NC_000962 55694 57376 2 + 1683 hypothetical protein Rv0051 - none - gi|15607193 fig|83332.1.peg.52 CDS NC_000962 57408 57971 3 + 564 ThiJ/PfpI family protein - none - gi|15607194 fig|83332.1.peg.53 CDS NC_000962 58190 58480 2 + 291 SSU ribosomal protein S6p Ribosome SSU bacterial gi|15607195 fig|83332.1.peg.54 CDS NC_000962 58584 59078 3 + 495 Single-stranded DNA-binding protein DNA repair, bacterial;
DNA repair, bacterial RecFOR pathway gi|15607196 fig|83332.1.peg.55 CDS NC_000962 59120 59374 2 + 255 SSU ribosomal protein S18p @ SSU ribosomal protein S18p, zinc-dependent Ribosome SSU bacterial;
Ribosome SSU bacterial gi|15607197 fig|83332.1.peg.56 CDS NC_000962 59407 59865 1 + 459 LSU ribosomal protein L9p Ribosome LSU bacterial gi|15607198 fig|83332.1.peg.57 CDS NC_000962 59894 60415 2 + 522 hypothetical protein Rv0057 - none - gi|15607199 fig|83332.1.peg.58 CDS NC_000962 60394 63018 1 + 2625 Replicative DNA helicase (DnaB) (EC 3.6.4.12) @ intein-containing Inteins gi|15607200 fig|83332.1.peg.59 CDS NC_000962 63198 63890 3 + 693 hypothetical protein Rv0059 - none - gi|15607201 fig|83332.1.peg.60 CDS NC_000962 63907 64965 1 + 1059 ADP-ribose 1"-phosphate phophatase related protein - none - gi|15607202 fig|83332.1.peg.61 CDS NC_000962 64989 65414 3 + 426 hypothetical protein Rv0061 - none - gi|15607203 fig|83332.1.peg.62 CDS NC_000962 65550 66692 3 + 1143 (MTV030.05), possible cellulase, len: 380; celA, similar to many eg. GUN1_STRHA P33682 endoglucanase 1precursor (ec 3.2.1.4) (cellulase) from STREPTOMYCES HALSTEDII (321 aa), fasta scores; opt: 702 z-score: 625.7 E(): 1.2e-27, 38.9% identity in 319 aa overlap - none - gi|15607204 fig|83332.1.peg.63 CDS NC_000962 66921 68360 3 + 1440 hypothetical protein Rv0063 - none - gi|15607205 fig|83332.1.peg.64 CDS NC_000962 68618 71557 2 + 2940 UPF0182 protein AF1421 - none - gi|15607206 fig|83332.1.peg.65 CDS NC_000962 71819 72220 2 + 402 Toxin 1, PIN domain Toxin-Antitoxin MT1 gi|15607207 fig|83332.1.peg.66 CDS NC_000962 74509 72272 -1 - 2238 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42); Monomeric isocitrate dehydrogenase [NADP] (EC 1.1.1.42) 5-FCL-like protein;
TCA Cycle gi|15607208 fig|83332.1.peg.67 CDS NC_000962 75196 74627 -1 - 570 Transcriptional regulator, TetR family - none - gi|15607209 fig|83332.1.peg.68 CDS NC_000962 75299 76210 2 + 912 Oxidoreductase, short-chain dehydrogenase/reductase family - none - gi|15607210 fig|83332.1.peg.69 CDS NC_000962 77620 76235 -1 - 1386 L-serine dehydratase, beta subunit (EC 4.3.1.17) / L-serine dehydratase, alpha subunit (EC 4.3.1.17) Glycine and Serine Utilization;
Glycine and Serine Utilization;
Pyruvate Alanine Serine Interconversions gi|15607211 fig|83332.1.peg.70 CDS NC_000962 78894 77617 -3 - 1278 Serine hydroxymethyltransferase (EC 2.1.2.1) 5-FCL-like protein;
Folate Biosynthesis;
Glycine Biosynthesis;
Glycine and Serine Utilization;
Glycine cleavage system;
Serine-glyoxylate cycle;
Serine Biosynthesis;
YrdC-YciO-Sua5 protein family gi|15607212 fig|83332.1.peg.71 CDS NC_000962 79484 80191 2 + 708 Retron-type RNA-directed DNA polymerase (EC 2.7.7.49) Group II intron-associated genes gi|15607213 fig|83332.1.peg.72 CDS NC_000962 80622 81671 3 + 1050 hypothetical protein Rv0072 - none - gi|15607214 fig|83332.1.peg.73 CDS NC_000962 81674 82666 2 + 993 hypothetical protein Rv0073 - none - gi|15607215 fig|83332.1.peg.74 CDS NC_000962 82746 83981 3 + 1236 Xaa-Pro dipeptidase (EC 3.4.13.9) - none - gi|15607216 fig|83332.1.peg.75 CDS NC_000962 83994 85166 3 + 1173 Cystathionine beta-lyase, type II (EC 4.4.1.8) - none - gi|15607217 fig|83332.1.peg.76 CDS NC_000962 85570 85181 -1 - 390 hypothetical protein Rv0076c - none - gi|15607218 fig|83332.1.peg.77 CDS NC_000962 86464 85634 -1 - 831 hypothetical protein Rv0077c - none - gi|15607219 fig|83332.1.peg.78 CDS NC_000962 86526 87131 3 + 606 Transcriptional regulator, TetR family - none - gi|15607220 fig|83332.1.peg.79 CDS NC_000962 88202 89023 2 + 822 hypothetical protein Rv0079 - none - gi|15607221 fig|83332.1.peg.80 CDS NC_000962 89020 89478 1 + 459 hypothetical protein Rv0080 - none - gi|15607222 fig|83332.1.peg.81 CDS NC_000962 89573 89917 2 + 345 transcriptional regulator, ArsR family - none - gi|15607223 fig|83332.1.peg.82 CDS NC_000962 89922 90401 3 + 480 Formate hydrogenlyase subunit 7 Formate hydrogenase gi|15607224 fig|83332.1.peg.83 CDS NC_000962 90398 92320 2 + 1923 Hydrogenase-4 component B (EC 1.-.-.-) / Formate hydrogenlyase subunit 3 Formate hydrogenase;
Formate hydrogenase gi|15607225 fig|83332.1.peg.84 CDS NC_000962 92326 93276 1 + 951 Formate hydrogenlyase subunit 4 Formate hydrogenase gi|15607226 fig|83332.1.peg.85 CDS NC_000962 93287 93949 2 + 663 Hydrogenase-4 component E (EC 1.-.-.-) Formate hydrogenase gi|15607227 fig|83332.1.peg.86 CDS NC_000962 93949 95415 1 + 1467 Hydrogenase-4 component F (EC 1.-.-.-) Formate hydrogenase gi|15607228 fig|83332.1.peg.87 CDS NC_000962 95412 96890 3 + 1479 Formate hydrogenlyase subunit 5 Formate hydrogenase gi|15607229 fig|83332.1.peg.88 CDS NC_000962 96925 97599 1 + 675 hypothetical protein Rv0088 - none - gi|15607230 fig|83332.1.peg.89 CDS NC_000962 97756 98349 1 + 594 hypothetical protein Rv0089 - none - gi|15607231 fig|83332.1.peg.90 CDS NC_000962 98478 99248 3 + 771 hypothetical protein Rv0090 - none - gi|15607232 fig|83332.1.peg.91 CDS NC_000962 99682 100449 1 + 768 5'-methylthioadenosine nucleosidase (EC 3.2.2.16) / S-adenosylhomocysteine nucleosidase (EC 3.2.2.9) Adenosyl nucleosidases;
Adenosyl nucleosidases;
Methionine Biosynthesis;
Methionine Degradation;
Polyamine Metabolism;
dNTP triphosphohydrolase protein family gi|15607233 fig|83332.1.peg.92 CDS NC_000962 100581 102866 3 + 2286 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) Copper Transport System;
Copper homeostasis;
Terminal cytochrome C oxidases gi|15607234 fig|83332.1.peg.93 CDS NC_000962 103661 102813 -2 - 849 hypothetical protein Rv0093c - none - gi|15607235 fig|83332.1.peg.94 CDS NC_000962 104661 103708 -3 - 954 hypothetical protein Rv0094c - none - gi|15607236 fig|83332.1.peg.95 CDS NC_000962 105213 104803 -3 - 411 hypothetical protein Rv0095c - none - gi|15607237 fig|83332.1.peg.96 CDS NC_000962 105322 106713 1 + 1392 PPE FAMILY PROTEIN - none - gi|15607238 fig|83332.1.peg.97 CDS NC_000962 106732 107601 1 + 870 hypothetical protein Rv0097 - none - gi|15607239 fig|83332.1.peg.98 CDS NC_000962 107598 108149 3 + 552 hypothetical protein Rv0098 - none - gi|15607240 fig|83332.1.peg.99 CDS NC_000962 108154 109776 1 + 1623 Long-chain fatty-acid-CoA ligase (EC 6.2.1.3), Mycobacterial subgroup FadD10 - none - gi|15607241 fig|83332.1.peg.100 CDS NC_000962 109781 110017 2 + 237 hypothetical protein Rv0100 - none - gi|15607242 fig|83332.1.peg.101 CDS NC_000962 109999 117537 1 + 7539 Enterobactin synthetase component F (EC 2.7.7.-) - none - gi|15607243 fig|83332.1.peg.102 CDS NC_000962 117712 119697 1 + 1986 Copper resistance protein CopD / Cytochrome c oxidase caa3-type, assembly factor CtaG-related protein Copper Transport System;
Copper homeostasis gi|15607244 fig|83332.1.peg.103 CDS NC_000962 122171 119913 -2 - 2259 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) Copper Transport System;
Copper homeostasis;
Terminal cytochrome C oxidases gi|15607245 fig|83332.1.peg.104 CDS NC_000962 122315 123829 2 + 1515 hypothetical protein - none - gi|15607246 fig|83332.1.peg.105 CDS NC_000962 124262 123978 -2 - 285 LSU ribosomal protein L28p Ribosome LSU bacterial gi|15607247 fig|83332.1.peg.106 CDS NC_000962 124372 125568 1 + 1197 Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family G3E family of P-loop GTPases (metallocenter biosynthesis) gi|15607248 fig|83332.1.peg.107 CDS NC_000962 130539 125641 -3 - 4899 (MTCY251.26c-MTV031.01c), len: 1632, ctpI,similar to cation transport atpases, eg ATA1_SYNY P37367 cation-transporting atpase pma1 (915 aa) FASTA scores, opt:603, z-score: 636.5, E(): 6.6e-29, (32.4% identity in 710 aaoverlap), contains PS00154 E1-E2 ATPases phosphorylationsite;also similar to MTCY39.21c and MTCY22G10.22c, (34.4% identity in 796 aa overlap) - none - gi|15607249 fig|83332.1.peg.108 CDS NC_000962 131102 130893 -2 - 210 hypothetical protein Rv0108c - none - gi|15607250 fig|83332.1.peg.109 CDS NC_000962 131380 132870 1 + 1491 (MTV031.03c), len: 496. Member of M. tuberculosis PE-family, Gly-, Ala-rich PGRS subfamily. FASTA scores: sp|Q50615|Y0DP_MYCTU HYPOTHETICAL GLYCINE-RICH 40.8 KD (498 aa) opt: 1772 z-score: 1133.2 E(): 0; 57.3% identity in 513 aa overlap. TBparse score is 0.884 - none - gi|15607251 fig|83332.1.peg.110 CDS NC_000962 133018 133767 1 + 750 FIG056164: rhomboid family serine protease Peptidyl-prolyl cis-trans isomerase containing cluster gi|15607252 fig|83332.1.peg.111 CDS NC_000962 133948 136005 1 + 2058 hypothetical protein Rv0111 - none - gi|15607253 fig|83332.1.peg.112 CDS NC_000962 136287 137243 3 + 957 GDP-mannose 4,6-dehydratase (EC 4.2.1.47) - none - gi|15607254 fig|83332.1.peg.113 CDS NC_000962 137317 137907 1 + 591 Phosphoheptose isomerase (EC 5.3.1.-) Capsular heptose biosynthesis gi|15607255 fig|83332.1.peg.114 CDS NC_000962 137939 138511 2 + 573 Phosphoheptose isomerase (EC 5.3.1.-) Capsular heptose biosynthesis gi|15607256 fig|83332.1.peg.115 CDS NC_000962 138511 139671 1 + 1161 D,D-heptose 7-phosphate kinase Capsular heptose biosynthesis gi|15607257 fig|83332.1.peg.116 CDS NC_000962 141020 140265 -2 - 756 hypothetical protein Rv0116c - none - gi|15607258 fig|83332.1.peg.117 CDS NC_000962 141198 142142 3 + 945 (MTV031.11), len: 314. OxyS protein, probable regulatory protein. LysR family signature at N-terminus. FASTA scores: gp|AJ0001|MTAJ188_1 Mycobacterium tuberculosis oxyS gene (314 aa) opt: 2014 z-score: 2474.5 E(): 0. 99.7% identity in 314 aa overlap score is 0.931. Also contains helix-turn-helix motif at aa 17-38 (Score 1556, +4.49 SD) - none - gi|15607259 fig|83332.1.peg.118 CDS NC_000962 143874 142126 -3 - 1749 Probable oxalyl-CoA decarboxylase (EC 4.1.1.8) - none - gi|15607260 fig|83332.1.peg.119 CDS NC_000962 144047 145624 2 + 1578 Long-chain fatty-acid-CoA ligase (EC 6.2.1.3), Mycobacterial subgroup FadD7 - none - gi|15607261 fig|83332.1.peg.120 CDS NC_000962 147769 145625 -1 - 2145 Translation elongation factor G-related protein Translation elongation factor G family;
Translation elongation factors bacterial gi|15607262 fig|83332.1.peg.121 CDS NC_000962 148340 147906 -2 - 435 hypothetical protein Rv0121c - none - gi|15607263 fig|83332.1.peg.122 CDS NC_000962 148489 148857 1 + 369 hypothetical protein Rv0122 - none - gi|15607264 fig|83332.1.peg.123 CDS NC_000962 148854 149222 3 + 369 hypothetical protein Rv0123 - none - gi|15607265 fig|83332.1.peg.124 CDS NC_000962 149531 150994 2 + 1464 PE-PGRS FAMILY PROTEIN - none - gi|15607266 fig|83332.1.peg.125 CDS NC_000962 151146 152213 3 + 1068 (MTCI418B.07), len: 355. probable serine protease, highly similar to Mycobacterium paratuberculosis Q50320 34KDA protein precursor (361 aa), fasta scores; opt: 1689 z-score: 1566.8 E(): 0, 70.7% identity in 362 aa overlapand to eg. HHOB_ECOLI P31137 protease hhob precursor (355aa), fasta scores; opt: 400 z-score: 380.0 E(): 3.8e-14, 32.4% identity in 346 aa overlap. Contains PS00135 Serine proteases, trypsin family, serine active site. Has a possiblesignal sequence at the N-terminus - none - gi|15607267 fig|83332.1.peg.126 CDS NC_000962 152322 154127 3 + 1806 Trehalose synthase (EC 5.4.99.16) Trehalose Biosynthesis gi|15607268 fig|83332.1.peg.127 CDS NC_000962 154230 155597 3 + 1368 uncharacterized protein probably involved in trehalose biosynthesis - none - gi|15607269 fig|83332.1.peg.128 CDS NC_000962 155665 156444 1 + 780 hypothetical protein Rv0128 - none - gi|15607270 fig|83332.1.peg.129 CDS NC_000962 157598 156576 -2 - 1023 Antigen 85-C precursor (85C) (Antigen 85 complex C) (Ag85C) (Mycolyl transferase 85C) (EC 2.3.1.-) CBSS-83332.1.peg.3803 gi|15607271 fig|83332.1.peg.130 CDS NC_000962 157845 158300 3 + 456 hypothetical protein Rv0130 - none - gi|15607272 fig|83332.1.peg.131 CDS NC_000962 159656 158313 -2 - 1344 Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.8.1) - none - gi|15607273 fig|83332.1.peg.132 CDS NC_000962 160780 159698 -1 - 1083 Similar to F420-dependent glucose-6-phosphate dehydrogenase, BCG_0166c family - none - gi|15607274 fig|83332.1.peg.133 CDS NC_000962 160867 161472 1 + 606 hypothetical protein Rv0133 - none - gi|15607275 fig|83332.1.peg.134 CDS NC_000962 161769 162671 3 + 903 epoxide hydrolase - none - gi|15607276 fig|83332.1.peg.135 CDS NC_000962 163247 162642 -2 - 606 Transcriptional regulator, TetR family - none - gi|15607277 fig|83332.1.peg.136 CDS NC_000962 163364 164689 2 + 1326 Cytochrome P450 138 - none - gi|15607278 fig|83332.1.peg.137 CDS NC_000962 165258 164710 -3 - 549 Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11) Peptide methionine sulfoxide reductase gi|15607279 fig|83332.1.peg.138 CDS NC_000962 165321 165824 3 + 504 hypothetical protein Rv0138 - none - gi|15607280 fig|83332.1.peg.139 CDS NC_000962 165825 166847 3 + 1023 hypothetical protein Rv0139 - none - gi|15607281 fig|83332.1.peg.140 CDS NC_000962 166908 167288 3 + 381 COGs COG2343 - none - gi|15607282 fig|83332.1.peg.141 CDS NC_000962 167679 167269 -3 - 411 hypothetical protein Rv0141c - none - gi|15607283 fig|83332.1.peg.142 CDS NC_000962 167709 168635 3 + 927 hypothetical protein Rv0142 - none - gi|15607284 fig|83332.1.peg.143 CDS NC_000962 170180 168702 -2 - 1479 Chloride channel protein - none - gi|15607285 fig|83332.1.peg.144 CDS NC_000962 170282 171124 2 + 843 Transcriptional regulator, TetR family - none - gi|15607286 fig|83332.1.peg.145 CDS NC_000962 171213 172166 3 + 954 O-Methyltransferase involved in polyketide biosynthesis - none - gi|15607287 fig|83332.1.peg.146 CDS NC_000962 172209 173141 3 + 933 O-Methyltransferase involved in polyketide biosynthesis - none - gi|15607288 fig|83332.1.peg.147 CDS NC_000962 173236 174756 1 + 1521 Aldehyde dehydrogenase (EC 1.2.1.3) Glycerolipid and Glycerophospholipid Metabolism in Bacteria;
Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate gi|15607289 fig|83332.1.peg.148 CDS NC_000962 174831 175691 3 + 861 hypothetical protein Rv0148 - none - gi|15607290 fig|83332.1.peg.149 CDS NC_000962 175698 176666 3 + 969 hypothetical protein Rv0149 - none - gi|15607291 fig|83332.1.peg.150 CDS NC_000962 176950 176663 -1 - 288 hypothetical protein Rv0150c - none - gi|15607292 fig|83332.1.peg.151 CDS NC_000962 179307 177541 -3 - 1767 (MTCI5.25c), unknown, len: 588 aa, N-terminal region similar eg to PE_PGRS family MTV032_2 hypothetical glycine-rich protein, (468 aa) protein (opt: 1125 z-score: 996.2 E(): 0; 46.3% identity in 456 aa overlap, or MTCY493_24(42.5% identity in 558 aa overlap). also similar toupstream ORF MTCI5.26c (54.7 % identity in 464 aa overlap). Also shows similarity to C-terminal part of PPE family representative MTV049_21 ( 41.5% identity in 591 aa overlap) - none - gi|15607293 fig|83332.1.peg.152 CDS NC_000962 180894 179317 -3 - 1578 PE FAMILY PROTEIN - none - gi|15607294 fig|83332.1.peg.153 CDS NC_000962 181983 181153 -3 - 831 hypothetical protein Rv0153c - none - gi|15607295 fig|83332.1.peg.154 CDS NC_000962 183196 181985 -1 - 1212 (MTCI5.28c), len: 403 aa, fadE2, similar to the C-terminal region of sp|O01590|O01590 ACYL-COA DEHYDROGENASE (974 aa); FASTA scores: opt: 1150 z-score: 1384.7 E(): 0;50.0% identity in 402 aa overlap. Also similar to eg ACDS_MEGEL Q06319 acyl-coa dehydrogenase, short-chain s (383 aa),(35.0% identity in 306 aa overlap) - none - gi|15607296 fig|83332.1.peg.155 CDS NC_000962 183620 184720 2 + 1101 NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2) ## N-domain NAD and NADP cofactor biosynthesis global;
Phosphate metabolism gi|15607297 fig|83332.1.peg.156 CDS NC_000962 184721 185053 2 + 333 NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2) NAD and NADP cofactor biosynthesis global;
Phosphate metabolism gi|15607298 fig|83332.1.peg.157 CDS NC_000962 185050 186477 1 + 1428 NAD(P) transhydrogenase subunit beta (EC 1.6.1.2) NAD and NADP cofactor biosynthesis global;
Phosphate metabolism gi|15607299 fig|83332.1.peg.158 CDS NC_000962 186783 187427 3 + 645 Transcriptional regulator, TetR family - none - gi|15607300 fig|83332.1.peg.159 CDS NC_000962 188837 187431 -2 - 1407 (MTV032.02c), len: 468. Member of M. tuberculosis PE family, similar to many other PE proteins e.g O06828 (528 aa). FASTA scores: sptr|O06828|O06828 HYPOTHETICAL 54.6 KD PROTEIN (528 aa) opt: 1163 z-score: 1226.5 E(): 0; 45.8% identity in 467 aa overlap. Also highly similar to upstream MTV032_3, and to MTCI5_25, MTCI5_26, MTV049_21, MTCY1A10_26 - none - gi|15607301 fig|83332.1.peg.160 CDS NC_000962 190437 188929 -3 - 1509 (MTV032.03c), len: 502. Member of M. tuberculosis PE family, similar to many other PE proteins e.g. O06801 (525 aa). Also highly similar to downstream ORF MTV032_2. Similar in C-terminal region to MTCI5.26c (525 aa). FASTA scores: sptr|O06801|O06801 HYPOTHETICAL 52.0 KD PROTEIN(618 aa) opt: 417 z-score: 455.9 E(): 6.7e-18; 53.5% identity in 142 aa overlap and Z92770|MTCI5_26 (525 aa) opt:816 z-score: 890.9 E(): 0; 41.4% identity in 367 aa overlap. - none - gi|15607302 fig|83332.1.peg.161 CDS NC_000962 190605 191954 3 + 1350 FAD/FMN-containing dehydrogenases - none - gi|15607303 fig|83332.1.peg.162 CDS NC_000962 193133 191982 -2 - 1152 Alcohol dehydrogenase (EC 1.1.1.1) - none - gi|15607304 fig|83332.1.peg.163 CDS NC_000962 193115 193570 2 + 456 hypothetical protein Rv0163 - none - gi|15607305 fig|83332.1.peg.164 CDS NC_000962 193624 194181 1 + 558 hypothetical protein - none - gi|15611065 fig|83332.1.peg.165 CDS NC_000962 194936 194142 -2 - 795 Transcriptional regulator, GntR family - none - gi|15607306 fig|83332.1.peg.166 CDS NC_000962 194991 196655 3 + 1665 Long-chain fatty-acid-CoA ligase (EC 6.2.1.3), Mycobacterial subgroup FadD5 Mycobacterium virulence operon MCE involved in cell invasion gi|15607307 fig|83332.1.peg.167 CDS NC_000962 196859 197656 2 + 798 Conserved hypothetical integral membrane protein YrbE1A Mycobacterium virulence operon MCE involved in cell invasion gi|15607308 fig|83332.1.peg.168 CDS NC_000962 197658 198527 3 + 870 Conserved hypothetical integral membrane protein YrbE1B Mycobacterium virulence operon MCE involved in cell invasion gi|15607309 fig|83332.1.peg.169 CDS NC_000962 198532 199896 1 + 1365 MCE-family protein Mce1A Mycobacterium virulence operon MCE involved in cell invasion gi|15607310 fig|83332.1.peg.170 CDS NC_000962 199893 200933 3 + 1041 MCE-family protein Mce1B Mycobacterium virulence operon MCE involved in cell invasion gi|15607311 fig|83332.1.peg.171 CDS NC_000962 200930 202477 2 + 1548 MCE-family protein Mce1C Mycobacterium virulence operon MCE involved in cell invasion gi|15607312 fig|83332.1.peg.172 CDS NC_000962 202474 204066 1 + 1593 MCE-family protein Mce1D Mycobacterium virulence operon MCE involved in cell invasion gi|15607313 fig|83332.1.peg.173 CDS NC_000962 204063 205235 3 + 1173 MCE-family lipoprotein LprK (MCE-family lipoprotein Mce1e) Mycobacterium virulence operon MCE involved in cell invasion gi|15607314 fig|83332.1.peg.174 CDS NC_000962 205229 206776 2 + 1548 MCE-family protein Mce1F Mycobacterium virulence operon MCE involved in cell invasion gi|15607315 fig|83332.1.peg.175 CDS NC_000962 206812 207453 1 + 642 FIG033430: Probable conserved MCE associated membrane protein Mycobacterium virulence operon MCE involved in cell invasion gi|15607316 fig|83332.1.peg.176 CDS NC_000962 207450 208418 3 + 969 FIG033285: Conserved MCE associated transmembrane protein Mycobacterium virulence operon MCE involved in cell invasion gi|15607317 fig|83332.1.peg.177 CDS NC_000962 208415 208969 2 + 555 FIG034772: Probable conserved MCE associated protein Mycobacterium virulence operon MCE involved in cell invasion gi|15607318 fig|83332.1.peg.178 CDS NC_000962 208936 209670 1 + 735 FIG030769: Probable conserved MCE associated membrane protein Mycobacterium virulence operon MCE involved in cell invasion gi|15607319 fig|83332.1.peg.179 CDS NC_000962 210810 209701 -3 - 1110 (MTCI28.19c), len: 369 aa; possible lipoprotein, contains possible M-terminal signal sequencem and contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site - none - gi|15607320 fig|83332.1.peg.180 CDS NC_000962 212248 210890 -1 - 1359 hypothetical protein Rv0180c - none - gi|15607321 fig|83332.1.peg.181 CDS NC_000962 213009 212275 -3 - 735 hypothetical protein Rv0181c - none - gi|15607322 fig|83332.1.peg.182 CDS NC_000962 214138 213026 -1 - 1113 (MTCI28.22c), len: 370; sigG, probable RNA polymerase sigma subunit, similar to many. e.g. RPOE_MYCTU RNA POLYMERASE SIGMA-E . Contains PS01063 Sigma-70 factors ECF subfamily signature and probable helix-turn helix motiffrom aa 206-227. Start site uncertain; first of several possibles was chosen, but note that this overlaps the upstream ORF. Also similar to two other M. tuberculosis sigma factors MTCY07D11.03 (28.1% identity in 221 aa overlap) and MTCY49.08 (30.1% identity in 173 aa overlap) - none - gi|15607323 fig|83332.1.peg.183 CDS NC_000962 213954 214925 3 + 972 Lysophospholipase (EC 3.1.1.5); Monoglyceride lipase (EC 3.1.1.23); putative Glutathione analogs: mycothiol;
Triacylglycerol metabolism;
Triacylglycerol metabolism gi|15607324 fig|83332.1.peg.184 CDS NC_000962 214967 215716 2 + 750 hypothetical protein Rv0184 - none - gi|15607325 fig|83332.1.peg.185 CDS NC_000962 215713 216222 1 + 510 hypothetical protein Rv0185 - none - gi|15607326 fig|83332.1.peg.186 CDS NC_000962 216267 218342 3 + 2076 Beta-glucosidase (EC 3.2.1.21) - none - gi|15607327 fig|83332.1.peg.187 CDS NC_000962 218703 219365 3 + 663 hypothetical protein Rv0187 - none - gi|15607328 fig|83332.1.peg.188 CDS NC_000962 219484 219915 1 + 432 hypothetical protein Rv0188 - none - gi|15607329 fig|83332.1.peg.189 CDS NC_000962 221721 219994 -3 - 1728 Dihydroxy-acid dehydratase (EC 4.2.1.9) Branched-Chain Amino Acid Biosynthesis gi|15607330 fig|83332.1.peg.190 CDS NC_000962 221869 222159 1 + 291 hypothetical protein Rv0190 - none - gi|15607331 fig|83332.1.peg.191 CDS NC_000962 222287 223528 2 + 1242 hypothetical protein Rv0191 - none - gi|15607332 fig|83332.1.peg.192 CDS NC_000962 223562 224662 2 + 1101 hypothetical protein Rv0192 - none - gi|15607333 fig|83332.1.peg.193 CDS NC_000962 226569 224722 -3 - 1848 hypothetical protein Rv0193c - none - gi|15607334 fig|83332.1.peg.194 CDS NC_000962 226876 230460 1 + 3585 hypothetical protein Rv0194 - none - gi|15607335 fig|83332.1.peg.195 CDS NC_000962 230897 231532 2 + 636 hypothetical protein Rv0195 - none - gi|15607336 fig|83332.1.peg.196 CDS NC_000962 231645 232229 3 + 585 Transcriptional regulator, TetR family - none - gi|15607337 fig|83332.1.peg.197 CDS NC_000962 232229 234517 2 + 2289 Formate dehydrogenase-O, major subunit (EC 1.2.1.2) Formate hydrogenase gi|15607338 fig|83332.1.peg.198 CDS NC_000962 236505 234514 -3 - 1992 hypothetical protein Rv0198c - none - gi|15607339 fig|83332.1.peg.199 CDS NC_000962 236548 237207 1 + 660 hypothetical protein Rv0199 - none - gi|15607340 fig|83332.1.peg.200 CDS NC_000962 237204 237893 3 + 690 hypothetical protein Rv0200 - none - gi|15607341 fig|83332.1.peg.201 CDS NC_000962 238393 237890 -1 - 504 hypothetical protein Rv0201c - none - gi|15607342 fig|83332.1.peg.202 CDS NC_000962 241290 238390 -3 - 2901 (MTV033.10c), len: 966. Probable membrane transport protein equivalent to Mycobacterium leprae MLCL622.16c (1014 aa) and similar to several putative transport proteins e.g. Bacillus subtilis P96687 (724 aa). FASTA scores: Z95398|MLCL622_16 (1014 aa) opt: 4076 z-score: 4470.3 E(): 0; 72.8% identity in 1017 aa overlap; and sptr|P96687|P96687 SIMILAR TO ANTIBIOTIC TRANSPORT-ASS (724 aa) opt:594 z-score:651.1 E(): 9.1e-29; 26.9% identity in 717 aaoverlap. TBparse score is 0.913 - none - gi|15607343 fig|83332.1.peg.203 CDS NC_000962 241512 241922 3 + 411 hypothetical protein Rv0203 - none - gi|15607344 fig|83332.1.peg.204 CDS NC_000962 243212 241974 -2 - 1239 hypothetical protein Rv0204c - none - gi|15607345 fig|83332.1.peg.205 CDS NC_000962 243382 244485 1 + 1104 hypothetical protein Rv0205 - none - gi|15607346 fig|83332.1.peg.206 CDS NC_000962 247316 244482 -2 - 2835 (MTV033.14c-MTCY08D5.01c), len: 944. Possible mebrane transport protein equivalent to Mycobacterium leprae MLCL622.18c (955 aa). FASTA scores: Z95398|MLCL622_18(955 aa) opt: 806 z-score: 520.0 E(): 1.8e-21; 57.2% identity in 243 aa overlap. TBparse score is 0.928 - none - gi|15607347 fig|83332.1.peg.207 CDS NC_000962 248110 247382 -1 - 729 hypothetical protein Rv0207c - none - gi|15607348 fig|83332.1.peg.208 CDS NC_000962 248904 248113 -3 - 792 tRNA (guanine46-N7-)-methyltransferase (EC 2.1.1.33) RNA methylation;
tRNA modification Bacteria gi|15607349 fig|83332.1.peg.209 CDS NC_000962 249036 250121 3 + 1086 FIG032248: hypothetical protein CBSS-336982.3.peg.219 gi|15607350 fig|83332.1.peg.210 CDS NC_000962 250118 251596 2 + 1479 FIG033897: hypothetical protein CBSS-336982.3.peg.219 gi|15607351 fig|83332.1.peg.211 CDS NC_000962 251780 253600 2 + 1821 Phosphoenolpyruvate carboxykinase [GTP] (EC 4.1.1.32) CBSS-336982.3.peg.219;
Pyruvate metabolism I: anaplerotic reactions, PEP gi|15607352 fig|83332.1.peg.212 CDS NC_000962 254638 253667 -1 - 972 Nicotinamide-nucleotide adenylyltransferase, NadR family (EC 2.7.7.1) / Ribosylnicotinamide kinase (EC 2.7.1.22) NAD and NADP cofactor biosynthesis global;
NAD and NADP cofactor biosynthesis global gi|15607353 fig|83332.1.peg.213 CDS NC_000962 255948 254635 -3 - 1314 hypothetical protein Rv0213c - none - gi|15607354 fig|83332.1.peg.214 CDS NC_000962 256062 257675 3 + 1614 Long-chain fatty-acid-CoA ligase (EC 6.2.1.3), Mycobacterial subgroup FadD4 - none - gi|15607355 fig|83332.1.peg.215 CDS NC_000962 258854 257781 -2 - 1074 Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.8.1) Isoleucine degradation gi|15607356 fig|83332.1.peg.216 CDS NC_000962 258911 259924 2 + 1014 Mesaconyl-CoA hydratase - none - gi|15607357 fig|83332.1.peg.217 CDS NC_000962 260829 259921 -3 - 909 Esterase LipW - none - gi|15607358 fig|83332.1.peg.218 CDS NC_000962 260922 262250 3 + 1329 hypothetical protein Rv0218 - none - gi|15607359 fig|83332.1.peg.219 CDS NC_000962 262252 262800 1 + 549 PROBABLE CONSERVED TRANSMEMBRANE PROTEIN - none - gi|15607360 fig|83332.1.peg.220 CDS NC_000962 262810 264021 1 + 1212 Esterase LipC - none - gi|15607361 fig|83332.1.peg.221 CDS NC_000962 264065 265474 2 + 1410 Diacyglycerol O-acyltransferase (EC 2.3.1.20) - none - gi|15607362 fig|83332.1.peg.222 CDS NC_000962 265505 266293 2 + 789 Enoyl-CoA hydratase (EC 4.2.1.17) Acetyl-CoA fermentation to Butyrate;
Butanol Biosynthesis;
Fatty acid metabolism cluster;
Isoleucine degradation;
Polyhydroxybutyrate metabolism;
Valine degradation gi|15607363 fig|83332.1.peg.223 CDS NC_000962 267762 266299 -3 - 1464 hypothetical protein Rv0223c - none - gi|15607364 fig|83332.1.peg.224 CDS NC_000962 268625 267861 -2 - 765 hypothetical protein Rv0224c - none - gi|15607365 fig|83332.1.peg.225 CDS NC_000962 268661 269815 2 + 1155 Glycosyltransferase (EC 2.4.1.-) - none - gi|15607366 fig|83332.1.peg.226 CDS NC_000962 271562 269832 -2 - 1731 hypothetical protein Rv0226c - none - gi|15607367 fig|83332.1.peg.227 CDS NC_000962 272837 271572 -2 - 1266 hypothetical protein Rv0227c - none - gi|15607368 fig|83332.1.peg.228 CDS NC_000962 273053 274276 2 + 1224 hypothetical protein Rv0228 - none - gi|15607369 fig|83332.1.peg.229 CDS NC_000962 274984 274304 -1 - 681 hypothetical protein Rv0229c - none - gi|15607370 fig|83332.1.peg.230 CDS NC_000962 275961 274981 -3 - 981 hypothetical protein Rv0230c - none - gi|15607371 fig|83332.1.peg.231 CDS NC_000962 276056 277762 2 + 1707 Acyl-CoA dehydrogenase (EC 1.3.8.7) - none - gi|15607372 fig|83332.1.peg.232 CDS NC_000962 277897 278586 1 + 690 Transcriptional regulator, TetR family - none - gi|15607373 fig|83332.1.peg.233 CDS NC_000962 278583 279527 3 + 945 NrdB - none - gi|15607374 fig|83332.1.peg.234 CDS NC_000962 281138 279603 -2 - 1536 Succinate-semialdehyde dehydrogenase [NAD] (EC 1.2.1.24); Succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16) - none - gi|15607375 fig|83332.1.peg.235 CDS NC_000962 282612 281164 -3 - 1449 hypothetical protein Rv0235c - none - gi|15607376 fig|83332.1.peg.236 CDS NC_000962 286849 282647 -1 - 4203 hypothetical protein Rv0236c - none - gi|15607377 fig|83332.1.peg.237 CDS NC_000962 287184 288350 3 + 1167 Beta-hexosaminidase (EC 3.2.1.52) - none - gi|15607378 fig|83332.1.peg.238 CDS NC_000962 288426 289040 3 + 615 Transcriptional regulator, TetR family - none - gi|15607379 fig|83332.1.peg.239 CDS NC_000962 289102 289335 1 + 234 hypothetical protein Rv0239 - none - gi|15607380 fig|83332.1.peg.240 CDS NC_000962 289343 289780 2 + 438 Toxin 1, PIN domain Toxin-Antitoxin MT1 gi|15607381 fig|83332.1.peg.241 CDS NC_000962 290652 289810 -3 - 843 Acyl dehydratase CBSS-246196.1.peg.364 gi|15607382 fig|83332.1.peg.242 CDS NC_000962 292027 290663 -1 - 1365 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) CBSS-164757.7.peg.5020;
CBSS-246196.1.peg.364;
Fatty Acid Biosynthesis FASII gi|15607383 fig|83332.1.peg.243 CDS NC_000962 292169 293491 2 + 1323 3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9) Acetyl-CoA fermentation to Butyrate;
Biotin biosynthesis;
Biotin synthesis cluster;
Butanol Biosynthesis;
CBSS-246196.1.peg.364;
Fatty acid metabolism cluster;
Isoleucine degradation;
Isoprenoid Biosynthesis;
Polyhydroxybutyrate metabolism;
Polyhydroxybutyrate metabolism;
Serine-glyoxylate cycle;
Serine-glyoxylate cycle gi|15607384 fig|83332.1.peg.244 CDS NC_000962 295631 293796 -2 - 1836 Acyl-CoA dehydrogenase (EC 1.3.8.7) - none - gi|15607385 fig|83332.1.peg.245 CDS NC_000962 296003 296491 2 + 489 NADH-FMN oxidoreductase - none - gi|15607386 fig|83332.1.peg.246 CDS NC_000962 296807 298117 2 + 1311 hypothetical protein Rv0246 - none - gi|15607387 fig|83332.1.peg.247 CDS NC_000962 298860 298114 -3 - 747 Succinate dehydrogenase iron-sulfur protein (EC 1.3.99.1) 5-FCL-like protein;
Serine-glyoxylate cycle;
Succinate dehydrogenase;
TCA Cycle gi|15607388 fig|83332.1.peg.248 CDS NC_000962 300801 298861 -3 - 1941 Succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1) Serine-glyoxylate cycle;
Succinate dehydrogenase;
TCA Cycle gi|15607389 fig|83332.1.peg.249 CDS NC_000962 301653 300832 -3 - 822 putative succinate dehydrogenase [membrane anchor subunit] (succinic dehydrogenase) Succinate dehydrogenase gi|15607390 fig|83332.1.peg.250 CDS NC_000962 302026 301733 -1 - 294 hypothetical protein Rv0250c - none - gi|15607391 fig|83332.1.peg.251 CDS NC_000962 302650 302171 -1 - 480 (MTV034.17c), len: 159. hsp, possibly heat shock protein belonging to HSP20 family, some similarity to many eukaryotic proteins e.g. CHLAMYDOMONAS REINHARDTII P12811|HS2C_CHLRE. Also similar to Synechocystis sp. PCC6803 Spore protein sp21 (146 aa). FASTA scores D90902|D90902_44 Synechocystis sp. PCC6803 complete (146 aa) opt: 213 z-score:271.7 E(): 1.2e-07; 30.3% identity in 145 aa overlap; and sp|P12811|HS2C_CHLRE CHLOROPLAST HEAT SHOCK 22KD PROT (157 aa) opt: 184 z-score: 236.3 E(): 1.2e-05;32.4% identity in 142 aa overla. TBparse score is 0.881 - none - gi|15607392 fig|83332.1.peg.252 CDS NC_000962 302864 305425 2 + 2562 Nitrite reductase [NAD(P)H] large subunit (EC 1.7.1.4) Nitrate and nitrite ammonification gi|15607393 fig|83332.1.peg.253 CDS NC_000962 305451 305807 3 + 357 Nitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4) Nitrate and nitrite ammonification gi|15607394 fig|83332.1.peg.254 CDS NC_000962 306347 305823 -2 - 525 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) Cobalamin synthesis;
Coenzyme B12 biosynthesis gi|15607395 fig|83332.1.peg.255 CDS NC_000962 307856 306372 -2 - 1485 Cobyric acid synthase (EC 6.3.5.10) Cobalamin synthesis;
Coenzyme B12 biosynthesis gi|15607396 fig|83332.1.peg.256 CDS NC_000962 309545 307875 -2 - 1671 Predicted cobalt transporter in Mycobacteria Coenzyme B12 biosynthesis;
Transport of Nickel and Cobalt gi|15607397 fig|83332.1.peg.257 CDS NC_000962 310258 309935 -1 - 324 hypothetical protein Rv0257c - none - gi|15607398 fig|83332.1.peg.258 CDS NC_000962 310747 310292 -1 - 456 hypothetical protein Rv0258c - none - gi|15607399 fig|83332.1.peg.259 CDS NC_000962 311515 310772 -1 - 744 Sirohydrochlorin ferrochelatase (EC 4.99.1.4) Heme and Siroheme Biosynthesis gi|15607400 fig|83332.1.peg.260 CDS NC_000962 312657 311512 -3 - 1146 Uroporphyrinogen-III synthase (EC 4.2.1.75) / response regulator - none - gi|15607401 fig|83332.1.peg.261 CDS NC_000962 314166 312757 -3 - 1410 Nitrate/nitrite transporter Nitrate and nitrite ammonification gi|15607402 fig|83332.1.peg.262 CDS NC_000962 314852 314307 -2 - 546 hypothetical protein Rv0262c - none - gi|15607403 fig|83332.1.peg.263 CDS NC_000962 315764 314862 -2 - 903 Allophanate hydrolase 2 subunit 2 (EC 3.5.1.54) EC699-706 gi|15607404 fig|83332.1.peg.264 CDS NC_000962 316413 315781 -3 - 633 Allophanate hydrolase 2 subunit 1 (EC 3.5.1.54) EC699-706 gi|15607405 fig|83332.1.peg.265 CDS NC_000962 317501 316509 -2 - 993 (MTCY06A4.09c), fecB2, iron transport protein, len: 330 aa, most similar to FECB_ECOLI P15028 iron(iii) dicitrate-binding periplasm (300 aa), fasta scores, opt:191, E(): 2.3e-05, (26.5% identity in 196 aa overlap). Alsosimilar to D90899_15 Synechocystis. Contains PS00013 Prokaryoticmembrane lipoprotein lipid attachment site - none - gi|15607406 fig|83332.1.peg.266 CDS NC_000962 321152 317523 -2 - 3630 Similar to 5-oxoprolinase (EC 3.5.2.9) and Methylhydantoinases A, B (EC 3.5.2.14), contradiction in experimental data (see Annotation) - none - gi|15607407 fig|83332.1.peg.267 CDS NC_000962 321329 322720 2 + 1392 Nitrate/nitrite transporter Nitrate and nitrite ammonification gi|15607408 fig|83332.1.peg.268 CDS NC_000962 323271 322762 -3 - 510 hypothetical protein Rv0268c - none - gi|15607409 fig|83332.1.peg.269 CDS NC_000962 324529 323336 -1 - 1194 hypothetical protein Rv0269c - none - gi|15607410 fig|83332.1.peg.270 CDS NC_000962 324565 326247 1 + 1683 Long-chain fatty-acid-CoA ligase (EC 6.2.1.3), Mycobacterial subgroup FadD2 - none - gi|15607411 fig|83332.1.peg.271 CDS NC_000962 328459 326264 -1 - 2196 Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.8.1) - none - gi|15607412 fig|83332.1.peg.272 CDS NC_000962 329706 328573 -3 - 1134 hypothetical protein Rv0272c - none - gi|15607413 fig|83332.1.peg.273 CDS NC_000962 330323 329703 -2 - 621 Transcriptional regulator, TetR family - none - gi|15607414 fig|83332.1.peg.274 CDS NC_000962 330420 331001 3 + 582 Glyoxalase family protein Serine-glyoxylate cycle gi|15607415 fig|83332.1.peg.275 CDS NC_000962 331656 330931 -3 - 726 Transcriptional regulator, TetR family - none - gi|15607416 fig|83332.1.peg.276 CDS NC_000962 331746 332666 3 + 921 hypothetical protein Rv0276 - none - gi|15607417 fig|83332.1.peg.277 CDS NC_000962 333134 332706 -2 - 429 Toxin 1, PIN domain Toxin-Antitoxin MT1 gi|15607418 fig|83332.1.peg.278 CDS NC_000962 336308 333435 -2 - 2874 (MTV035.06c), len: 957. Member of M. tuberculosis Gly-, Ala-rich PGRS subfamily of PE protein family.Similar tomany others. Contains PS00583 pfkB family of carbohydrate kinases signature 1. FASTA scores: Z95890|MTCY28_25 (914 aa) opt: 3849 z-score: 2368.8 E(): 0; 67.8% identity in 903 aa overlap. TBparse score is 0.870 - none - gi|15607419 fig|83332.1.peg.279 CDS NC_000962 339071 336558 -2 - 2514 (MTV035.07c), len: 837. Member of M. tuberculosis Gly-, Ala-rich PGRS subfamily of PE protein family.Similar to many others. FASTA scores: Z95890|MTCY28_25 Mycobacteriumtuberculosis cosmid (914 aa) opt: 2677 z-score:1625.3 E(): 0; 64.5% identity in 926 aa overlap. TBparse score is0.852 - none - gi|15607420 fig|83332.1.peg.280 CDS NC_000962 339362 340972 2 + 1611 PPE family protein CBSS-164757.7.peg.5020 gi|15607421 fig|83332.1.peg.281 CDS NC_000962 340996 341904 1 + 909 hypothetical protein Rv0281 - none - gi|15607422 fig|83332.1.peg.282 CDS NC_000962 342128 344023 2 + 1896 hypothetical protein Rv0282 - none - gi|15607423 fig|83332.1.peg.283 CDS NC_000962 344020 345636 1 + 1617 hypothetical protein Rv0283 - none - gi|15607424 fig|83332.1.peg.284 CDS NC_000962 345633 349625 3 + 3993 FtsK/SpoIIIE family protein - none - gi|15607425 fig|83332.1.peg.285 CDS NC_000962 349622 349930 2 + 309 (MTV035.13), len: 102. Unknown but member of large protein family found in Mycobacterium tuberculosis,PE family, containing MTV012_37 (105 aa), MTCY21B4.03 (102aa), etc. FASTA scores: gp|AL0212|MTV012_37 (105 aa) opt:497z-score: 571.1 E(): 2.6e-24; 80.4% identity in 102 aa overlap; and gp|Z80108|MTCY21B4_3 Mycobacterium tuberculosiscosmid (102 aa) opt: 413 z-score: 478.6 E(): 3.7e-19;66.7%identity in 102 aa overla. TBparse score is 0.858 - none - gi|15607426 fig|83332.1.peg.286 CDS NC_000962 349933 351474 1 + 1542 (MTV035.14), len: 513. Member of large Gly-Ala-rich protein family, PPE family, found in mycobacteria.FASTA scores: AL0212|MTV012_32 Mycobacterium tuberculosissequenc (434 aa) opt: 958 z-score: 781.7 E(): 0; 43.5%identityin 522 aa overlap. TBparse score is 0.929 - none - gi|15607427 fig|83332.1.peg.287 CDS NC_000962 351523 351816 1 + 294 ESAT-6 like protein EsxS - none - gi|15607428 fig|83332.1.peg.288 CDS NC_000962 351846 352136 3 + 291 hypothetical protein Rv0288 - none - gi|15607429 fig|83332.1.peg.289 CDS NC_000962 352147 353034 1 + 888 ESX-3 secretion-associated protein EspG3 - none - gi|15607430 fig|83332.1.peg.290 CDS NC_000962 353081 354499 2 + 1419 ESX-3 secretion system protein EccD3 - none - gi|15607431 fig|83332.1.peg.291 CDS NC_000962 354496 355881 1 + 1386 Type VII secretion-associated serine protease mycosin MycP3 - none - gi|15607432 fig|83332.1.peg.292 CDS NC_000962 355878 356873 3 + 996 ESX-3 secretion system protein EccE3 - none - gi|15607433 fig|83332.1.peg.293 CDS NC_000962 358062 356860 -3 - 1203 hypothetical protein Rv0293c - none - gi|15607434 fig|83332.1.peg.294 CDS NC_000962 358169 358954 2 + 786 Trans-aconitate 2-methyltransferase (EC 2.1.1.144) - none - gi|15607435 fig|83332.1.peg.295 CDS NC_000962 359746 358943 -1 - 804 Sulfotransferase - none - gi|15607436 fig|83332.1.peg.296 CDS NC_000962 361153 359756 -1 - 1398 (MTCY63.01c-MTV035.24c), len: 465, atsG, Function: unknown, but some similarity to aryl- and steryl-sulfatases. Contains sulfatases signature 1 (PS00523). FASTAresults:ARSB_FELCA P33727 arylsulfatase b precursor (ec 3.1.6.1) (535 aa) opt: 231; E(): 1.7e-08; 30.3% identity in 261 aa overlap. TBparse score is 0.918 - none - gi|15607437 fig|83332.1.peg.297 CDS NC_000962 361332 363107 3 + 1776 PE-PGRS family protein PPE gene cluster in Mycobacteria gi|15607438 fig|83332.1.peg.298 CDS NC_000962 363250 363477 1 + 228 Programmed cell death antitoxin YdcD MazEF toxin-antitoxing (programmed cell death) system;
Phd-Doc, YdcE-YdcD toxin-antitoxin (programmed cell death) systems gi|15607439 fig|83332.1.peg.299 CDS NC_000962 363474 363776 3 + 303 Programmed cell death toxin YdcE MazEF toxin-antitoxing (programmed cell death) system;
Phd-Doc, YdcE-YdcD toxin-antitoxin (programmed cell death) systems gi|15607440 fig|83332.1.peg.300 CDS NC_000962 363824 364045 2 + 222 hypothetical protein Rv0300 - none - gi|15607441 fig|83332.1.peg.301 CDS NC_000962 364042 364467 1 + 426 FIG036853: hypothetical protein - none - gi|15607442 fig|83332.1.peg.302 CDS NC_000962 364603 365235 1 + 633 TetR/ACRR family transcriptional regulator - none - gi|15607443 fig|83332.1.peg.303 CDS NC_000962 365232 366140 3 + 909 Oxidoreductase, short-chain dehydrogenase/reductase family - none - gi|15607444 fig|83332.1.peg.304 CDS NC_000962 372762 366148 -3 - 6615 PPE family protein - none - gi|15607445 fig|83332.1.peg.305 CDS NC_000962 375709 372818 -1 - 2892 PPE family protein - none - gi|15607446 fig|83332.1.peg.306 CDS NC_000962 375912 376583 3 + 672 Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family Cobalamin synthesis;
Coenzyme B12 biosynthesis gi|15607447 fig|83332.1.peg.307 CDS NC_000962 377053 376571 -1 - 483 hypothetical protein Rv0307c - none - gi|15607448 fig|83332.1.peg.308 CDS NC_000962 377111 377827 2 + 717 Possible membrane protein - none - gi|15607449 fig|83332.1.peg.309 CDS NC_000962 377929 378585 1 + 657 FIG019540: hypothetical protein - none - gi|15607450 fig|83332.1.peg.310 CDS NC_000962 379146 378655 -3 - 492 Bile acid 7-alpha dehydratase BaiE (EC 4.2.1.106) - none - gi|15607451 fig|83332.1.peg.311 CDS NC_000962 379170 380399 3 + 1230 hypothetical protein Rv0311 - none - gi|15607452 fig|83332.1.peg.312 CDS NC_000962 380554 382416 1 + 1863 Proline and threonine rich protein - none - gi|15607453 fig|83332.1.peg.313 CDS NC_000962 382488 382874 3 + 387 hypothetical protein Rv0313 - none - gi|15607454 fig|83332.1.peg.314 CDS NC_000962 383539 382877 -1 - 663 Possible membrane protein - none - gi|15607455 fig|83332.1.peg.315 CDS NC_000962 383600 384484 2 + 885 "Possible beta-1,3-glucanase" - none - gi|15607456 fig|83332.1.peg.316 CDS NC_000962 384533 385147 2 + 615 Muconolactone isomerase (EC 5.3.3.4) Catechol branch of beta-ketoadipate pathway;
Muconate lactonizing enzyme family gi|15607457 fig|83332.1.peg.317 CDS NC_000962 385941 385171 -3 - 771 Glycerophosphoryl diester phosphodiesterase (EC 3.1.4.46) Glycerol and Glycerol-3-phosphate Uptake and Utilization gi|15607458 fig|83332.1.peg.318 CDS NC_000962 387097 386303 -1 - 795 Possible membrane protein - none - gi|15607459 fig|83332.1.peg.319 CDS NC_000962 387146 387814 2 + 669 Pyrrolidone-carboxylate peptidase (EC 3.4.19.3) Omega peptidases (EC 3.4.19.-) gi|15607460 fig|83332.1.peg.320 CDS NC_000962 387886 388548 1 + 663 Possible conserved exported protein - none - gi|15607461 fig|83332.1.peg.321 CDS NC_000962 388580 389152 2 + 573 Deoxycytidine triphosphate deaminase (EC 3.5.4.30) (dUMP-forming) pyrimidine conversions gi|15607462 fig|83332.1.peg.322 CDS NC_000962 389258 390589 2 + 1332 UDP-glucose 6-dehydrogenase (EC 1.1.1.22) Inteins gi|15607463 fig|83332.1.peg.323 CDS NC_000962 391249 390578 -1 - 672 FIG030768: hypothetical protein - none - gi|15607464 fig|83332.1.peg.324 CDS NC_000962 391350 392030 3 + 681 Transcriptional regulator, ArsR family cAMP signaling in bacteria gi|15607465 fig|83332.1.peg.325 CDS NC_000962 392037 392261 3 + 225 FIG068839: hypothetical protein - none - gi|15607466 fig|83332.1.peg.326 CDS NC_000962 392271 392726 3 + 456 Methyltransferase (EC 2.1.1.-) - none - gi|15607467 fig|83332.1.peg.327 CDS NC_000962 394043 392694 -2 - 1350 Cytochrome P450 135A1 - none - gi|15607468 fig|83332.1.peg.328 CDS NC_000962 394109 394711 2 + 603 HTH-type transcriptional regulator BetI - none - gi|15607469 fig|83332.1.peg.329 CDS NC_000962 395318 394692 -2 - 627 FIG034077: hypothetical protein - none - gi|15607470 fig|83332.1.peg.330 CDS NC_000962 396085 395345 -1 - 741 Transcriptional regulator, TetR family - none - gi|15607471 fig|83332.1.peg.331 CDS NC_000962 396199 397365 1 + 1167 Oxidoreductase (flavoprotein) - none - gi|15607472 fig|83332.1.peg.332 CDS NC_000962 397440 398225 3 + 786 hypothetical protein Rv0332 - none - gi|15607473 fig|83332.1.peg.333 CDS NC_000962 398252 398626 2 + 375 hypothetical protein Rv0333 - none - gi|15607474 fig|83332.1.peg.334 CDS NC_000962 398656 399522 1 + 867 Glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) Rhamnose containing glycans;
dTDP-rhamnose synthesis gi|15607475 fig|83332.1.peg.335 CDS NC_000962 400048 399533 -1 - 516 PE family protein - none - gi|15607476 fig|83332.1.peg.336 CDS NC_000962 400190 401701 2 + 1512 13E12 repeat family protein - none - gi|15607477 fig|83332.1.peg.337 CDS NC_000962 403160 401871 -2 - 1290 Aspartate aminotransferase (EC 2.6.1.1) Proline, 4-hydroxyproline uptake and utilization gi|15607478 fig|83332.1.peg.338 CDS NC_000962 405839 403191 -2 - 2649 Fe-S oxidoreductase - none - gi|15607479 fig|83332.1.peg.339 CDS NC_000962 408446 405948 -2 - 2499 Transcriptional regulator - none - gi|15607480 fig|83332.1.peg.340 CDS NC_000962 408632 409171 2 + 540 hypothetical protein Rv0340 - none - gi|15607481 fig|83332.1.peg.341 CDS NC_000962 409360 410799 1 + 1440 Isoniazid inductible protein IniB - none - gi|15607482 fig|83332.1.peg.342 CDS NC_000962 410836 412758 1 + 1923 Isoniazid inductible protein IniA - none - gi|15607483 fig|83332.1.peg.343 CDS NC_000962 412755 414236 3 + 1482 Isoniazid inductible protein IniC - none - gi|15607484 fig|83332.1.peg.344 CDS NC_000962 414939 414379 -3 - 561 Lipoprotein LpqJ - none - gi|15607485 fig|83332.1.peg.345 CDS NC_000962 415048 415458 1 + 411 CTP:molybdopterin cytidylyltransferase Carbon monoxide oxidation;
Molybdenum cofactor biosynthesis gi|15607486 fig|83332.1.peg.346 CDS NC_000962 416963 415500 -2 - 1464 L-asparagine permease - none - gi|15607487 fig|83332.1.peg.347 CDS NC_000962 417302 418288 2 + 987 FIG047027: hypothetical protein - none - gi|15607488 fig|83332.1.peg.348 CDS NC_000962 418291 418944 1 + 654 FIG046367: hypothetical protein - none - gi|15607489 fig|83332.1.peg.349 CDS NC_000962 418947 419606 3 + 660 hypothetical protein - none - gi|15607490 fig|83332.1.peg.350 CDS NC_000962 419833 421710 1 + 1878 Chaperone protein DnaK GroEL GroES;
Heat shock dnaK gene cluster extended;
Protein chaperones gi|15607491 fig|83332.1.peg.351 CDS NC_000962 421707 422414 3 + 708 Heat shock protein GrpE GroEL GroES;
Heat shock dnaK gene cluster extended;
Protein chaperones gi|15607492 fig|83332.1.peg.352 CDS NC_000962 422450 423637 2 + 1188 Chaperone protein DnaJ GroEL GroES;
Heat shock dnaK gene cluster extended;
Protein chaperones gi|15607493 fig|83332.1.peg.353 CDS NC_000962 423637 424017 1 + 381 HspR, transcriptional repressor of DnaK operon Heat shock dnaK gene cluster extended;
Protein chaperones gi|15607494 fig|83332.1.peg.354 CDS NC_000962 424692 424267 -3 - 426 PPE family protein - none - gi|15607495 fig|83332.1.peg.355 CDS NC_000962 434677 424775 -1 - 9903 PPE family protein - none - gi|15607496 fig|83332.1.peg.356 CDS NC_000962 435472 434828 -1 - 645 hypothetical protein - none - gi|15607497 fig|83332.1.peg.357 CDS NC_000962 436767 435469 -3 - 1299 Adenylosuccinate synthetase (EC 6.3.4.4) Histidine Biosynthesis;
Purine conversions gi|15607498 fig|83332.1.peg.358 CDS NC_000962 436858 437505 1 + 648 hypothetical protein - none - gi|15607499 fig|83332.1.peg.359 CDS NC_000962 437516 438295 2 + 780 Possible membrane protein - none - gi|15607500 fig|83332.1.peg.360 CDS NC_000962 438737 438300 -2 - 438 hypothetical protein - none - gi|15607501 fig|83332.1.peg.361 CDS NC_000962 438820 439647 1 + 828 PROBABLE CONSERVED MEMBRANE PROTEIN - none - gi|15607502 fig|83332.1.peg.362 CDS NC_000962 439869 441251 3 + 1383 Mg/Co/Ni transporter MgtE / CBS domain Magnesium transport;
Purine salvage cluster gi|15607503 fig|83332.1.peg.363 CDS NC_000962 442297 441263 -1 - 1035 Fructose-bisphosphate aldolase class II (EC 4.1.2.13) Glycolysis and Gluconeogenesis gi|15607504 fig|83332.1.peg.364 CDS NC_000962 442393 443076 1 + 684 DedA protein DedA family of inner membrane proteins;
Uptake of selenate and selenite gi|15607505 fig|83332.1.peg.365 CDS NC_000962 444195 443065 -3 - 1131 fructose-bisphosphate aldolase family protein - none - gi|15607506 fig|83332.1.peg.366 CDS NC_000962 444813 444220 -3 - 594 hypothetical protein Rv0366c - none - gi|15607507 fig|83332.1.peg.367 CDS NC_000962 445231 444842 -1 - 390 hypothetical protein - none - gi|15607508 fig|83332.1.peg.368 CDS NC_000962 446523 445312 -3 - 1212 Carbon monoxide oxidation accessory protein CoxE CBSS-314269.3.peg.1840;
CO Dehydrogenase;
Carbon monoxide dehydrogenase maturation factors;
Carbon monoxide oxidation gi|15607509 fig|83332.1.peg.369 CDS NC_000962 447044 446529 -2 - 516 Carbon monoxide oxidation accessory protein CoxG CO Dehydrogenase;
Carbon monoxide dehydrogenase maturation factors;
Carbon monoxide oxidation gi|15607510 fig|83332.1.peg.370 CDS NC_000962 448041 447145 -3 - 897 Carbon monoxide oxidation accessory protein CoxD CBSS-314269.3.peg.1840;
CO Dehydrogenase;
Carbon monoxide dehydrogenase maturation factors;
Carbon monoxide oxidation gi|15607511 fig|83332.1.peg.371 CDS NC_000962 448631 448038 -2 - 594 CTP:molybdopterin cytidylyltransferase CO Dehydrogenase;
Carbon monoxide oxidation;
Molybdenum cofactor biosynthesis gi|15607512 fig|83332.1.peg.372 CDS NC_000962 449383 448628 -1 - 756 Aerobic carbon monoxide dehydrogenase molybdenum cofactor insertion protein CoxF CBSS-314269.3.peg.1840;
CO Dehydrogenase;
Carbon monoxide dehydrogenase maturation factors;
Carbon monoxide oxidation gi|15607513 fig|83332.1.peg.373 CDS NC_000962 451801 449402 -1 - 2400 Carbon monoxide dehydrogenase form I, large chain (EC 1.2.99.2) CBSS-314269.3.peg.1840;
CO Dehydrogenase;
Carbon monoxide oxidation gi|15607514 fig|83332.1.peg.374 CDS NC_000962 452277 451798 -3 - 480 Carbon monoxide dehydrogenase small chain (EC 1.2.99.2) CBSS-314269.3.peg.1840;
CO Dehydrogenase;
Carbon monoxide oxidation gi|15607515 fig|83332.1.peg.375 CDS NC_000962 453152 452292 -2 - 861 Carbon monoxide dehydrogenase medium chain (EC 1.2.99.2) CBSS-314269.3.peg.1840;
CO Dehydrogenase;
Carbon monoxide oxidation gi|15607516 fig|83332.1.peg.376 CDS NC_000962 454370 453228 -2 - 1143 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family CO Dehydrogenase;
Carbon monoxide oxidation;
Molybdenum cofactor biosynthesis gi|15607517 fig|83332.1.peg.377 CDS NC_000962 454419 455384 3 + 966 Transcription regulator in CO-DH cluster CBSS-314269.3.peg.1840;
CO Dehydrogenase;
Carbon monoxide oxidation gi|15607518 fig|83332.1.peg.378 CDS NC_000962 455635 455856 1 + 222 PE family protein - none - gi|15607519 fig|83332.1.peg.379 CDS NC_000962 455975 456190 2 + 216 Preprotein translocase subunit SecE2 - none - gi|15607520 fig|83332.1.peg.380 CDS NC_000962 456817 456266 -1 - 552 SpoU rRNA methylase family protein - none - gi|15607521 fig|83332.1.peg.381 CDS NC_000962 457821 456913 -3 - 909 hypothetical protein Rv0381c - none - gi|15607522 fig|83332.1.peg.382 CDS NC_000962 458378 457839 -2 - 540 Orotate phosphoribosyltransferase (EC 2.4.2.10) De Novo Pyrimidine Synthesis gi|15607523 fig|83332.1.peg.383 CDS NC_000962 459313 458459 -1 - 855 Possible membrane protein - none - gi|15607524 fig|83332.1.peg.384 CDS NC_000962 462000 459454 -3 - 2547 ClpB protein Protein chaperones;
Proteolysis in bacteria, ATP-dependent gi|15607525 fig|83332.1.peg.385 CDS NC_000962 462133 463305 1 + 1173 Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17) - none - gi|15607526 fig|83332.1.peg.386 CDS NC_000962 463409 466666 2 + 3258 Adenylyl cyclase class-3/4/guanylyl cyclase / Disease resistance domain-containing protein / Tetratricopeptide repeat-containing protein / Transcriptional regulator, LuxR family - none - gi|15607527 fig|83332.1.peg.387 CDS NC_000962 467404 466670 -1 - 735 hypothetical protein Rv0387c - none - gi|15607528 fig|83332.1.peg.388 CDS NC_000962 467999 467457 -2 - 543 PPE family protein - none - gi|15607529 fig|83332.1.peg.389 CDS NC_000962 468333 469592 3 + 1260 Phosphoribosylglycinamide formyltransferase 2 (EC 2.1.2.-) De Novo Purine Biosynthesis gi|15607530 fig|83332.1.peg.390 CDS NC_000962 469589 470011 2 + 423 hypothetical protein Rv0390 - none - gi|15607531 fig|83332.1.peg.391 CDS NC_000962 470008 471228 1 + 1221 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) Methionine Biosynthesis;
Methionine Biosynthesis gi|15607532 fig|83332.1.peg.392 CDS NC_000962 472637 471225 -2 - 1413 NADH dehydrogenase (EC 1.6.99.3) PPE gene cluster in Mycobacteria;
Respiratory dehydrogenases 1;
Riboflavin synthesis cluster gi|15607533 fig|83332.1.peg.393 CDS NC_000962 472779 474104 3 + 1326 13E12 repeat family protein - none - gi|15607534 fig|83332.1.peg.394 CDS NC_000962 474839 474120 -2 - 720 Possible membrane protein - none - gi|15607535 fig|83332.1.peg.395 CDS NC_000962 474938 475342 2 + 405 hypothetical protein Rv0395 - none - gi|15607536 fig|83332.1.peg.396 CDS NC_000962 475348 475740 1 + 393 hypothetical protein Rv0396 - none - gi|15607537 fig|83332.1.peg.397 CDS NC_000962 475814 476182 2 + 369 13E12 repeat family protein - none - gi|15607538 fig|83332.1.peg.398 CDS NC_000962 477318 476677 -3 - 642 Possible membrane protein - none - gi|15607539 fig|83332.1.peg.399 CDS NC_000962 478554 477325 -3 - 1230 alkaline D-peptidase - none - gi|15607540 fig|83332.1.peg.400 CDS NC_000962 479751 478564 -3 - 1188 Glutaryl-CoA dehydrogenase (EC 1.3.99.7) - none - gi|15607541 fig|83332.1.peg.401 CDS NC_000962 479787 480158 3 + 372 Possible membrane protein - none - gi|15607542 fig|83332.1.peg.402 CDS NC_000962 483229 480353 -1 - 2877 Transmembrane transport protein MmpL1 - none - gi|15607543 fig|83332.1.peg.403 CDS NC_000962 483654 483226 -3 - 429 membrane protein, MmpS family - none - gi|15607544 fig|83332.1.peg.404 CDS NC_000962 483975 485732 3 + 1758 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) Biotin biosynthesis;
Biotin synthesis cluster;
Fatty acid metabolism cluster gi|15607545 fig|83332.1.peg.405 CDS NC_000962 485729 489937 2 + 4209 Membrane bound polyketide synthase - none - gi|15607546 fig|83332.1.peg.406 CDS NC_000962 490703 489885 -2 - 819 Beta lactamase-like protein - none - gi|15607547 fig|83332.1.peg.407 CDS NC_000962 490781 491791 2 + 1011 F420-dependent glucose-6-phosphate dehydrogenase - none - gi|15607548 fig|83332.1.peg.408 CDS NC_000962 491784 493856 3 + 2073 Phosphate acetyltransferase (EC 2.3.1.8) Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate gi|15607549 fig|83332.1.peg.409 CDS NC_000962 493849 495006 1 + 1158 Acetate kinase (EC 2.7.2.1) Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate gi|15607550 fig|83332.1.peg.410 CDS NC_000962 497312 495060 -2 - 2253 Serine/threonine protein kinase - none - gi|15607551 fig|83332.1.peg.411 CDS NC_000962 498298 497312 -1 - 987 Glutamine ABC transporter, periplasmic glutamine-binding protein (TC 3.A.1.3.2) - none - gi|15607552 fig|83332.1.peg.412 CDS NC_000962 499617 498298 -3 - 1320 Possible membrane protein - none - gi|15607553 fig|83332.1.peg.413 CDS NC_000962 499711 500364 1 + 654 "Possible mutator protein MutT3 (7,8-dihydro-8-oxoguanine-triphosphatase) " - none - gi|15607554 fig|83332.1.peg.414 CDS NC_000962 501016 500348 -1 - 669 Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) 5-FCL-like protein;
Thiamin biosynthesis gi|15607555 fig|83332.1.peg.415 CDS NC_000962 501146 502168 2 + 1023 Glycine oxidase ThiO (EC 1.4.3.19) Thiamin biosynthesis gi|15607556 fig|83332.1.peg.416 CDS NC_000962 502165 502371 1 + 207 Sulfur carrier protein ThiS Thiamin biosynthesis gi|15607557 fig|83332.1.peg.417 CDS NC_000962 502364 503122 2 + 759 Thiazole biosynthesis protein ThiG Thiamin biosynthesis gi|15607558 fig|83332.1.peg.418 CDS NC_000962 503494 504996 1 + 1503 Aminopeptidase Y (Arg, Lys, Leu preference) (EC 3.4.11.15) Aminopeptidases (EC 3.4.11.-) gi|15607559 fig|83332.1.peg.419 CDS NC_000962 505084 506580 1 + 1497 Lipoprotein peptidase LpqM - none - gi|15607560 fig|83332.1.peg.420 CDS NC_000962 506969 506559 -2 - 411 Possible membrane protein - none - gi|15607561 fig|83332.1.peg.421 CDS NC_000962 507759 507130 -3 - 630 FIG022825: hypothetical protein - none - gi|15607562 fig|83332.1.peg.422 CDS NC_000962 508553 507756 -2 - 798 Phosphomethylpyrimidine kinase (EC 2.7.4.7) 5-FCL-like protein;
Thiamin biosynthesis gi|15607563 fig|83332.1.peg.423 CDS NC_000962 510223 508580 -1 - 1644 Thiamin biosynthesis protein ThiC Thiamin biosynthesis gi|15607564 fig|83332.1.peg.424 CDS NC_000962 510650 510375 -2 - 276 hypothetical protein Rv0424c - none - gi|15607565 fig|83332.1.peg.425 CDS NC_000962 515319 510700 -3 - 4620 Metal cation transporting P-type ATPase CtpH - none - gi|15607566 fig|83332.1.peg.426 CDS NC_000962 515814 515371 -3 - 444 Possible membrane protein - none - gi|15607567 fig|83332.1.peg.427 CDS NC_000962 516890 516015 -2 - 876 Exodeoxyribonuclease III (EC 3.1.11.2) DNA repair, bacterial gi|15607568 fig|83332.1.peg.428 CDS NC_000962 517801 516893 -1 - 909 Histone acetyltransferase HPA2 and related acetyltransferases - none - gi|15607569 fig|83332.1.peg.429 CDS NC_000962 518394 517801 -3 - 594 Peptide deformylase (EC 3.5.1.88) Bacterial RNA-metabolizing Zn-dependent hydrolases;
Conserved gene cluster associated with Met-tRNA formyltransferase;
Dehydrogenase complexes;
Translation termination factors bacterial gi|15607570 fig|83332.1.peg.430 CDS NC_000962 518731 519039 1 + 309 FIG00822394: hypothetical protein - none - gi|15607571 fig|83332.1.peg.431 CDS NC_000962 519071 519565 2 + 495 Tuberculin related peptide - none - gi|15607572 fig|83332.1.peg.432 CDS NC_000962 519598 520320 1 + 723 Superoxide dismutase [Cu-Zn] precursor (EC 1.15.1.1) Protection from Reactive Oxygen Species gi|15607573 fig|83332.1.peg.433 CDS NC_000962 520322 521452 2 + 1131 Carboxylate-amine ligase - none - gi|15607574 fig|83332.1.peg.434 CDS NC_000962 521512 522165 1 + 654 Uncharacterized protein, similar to the N-terminal domain of Lon protease - none - gi|15607575 fig|83332.1.peg.435 CDS NC_000962 524531 522345 -2 - 2187 Cell division protein FtsH (EC 3.4.24.-) Bacterial Cell Division;
Cell division-ribosomal stress proteins cluster;
Folate biosynthesis cluster gi|15607576 fig|83332.1.peg.436 CDS NC_000962 525388 524528 -1 - 861 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) Glycerolipid and Glycerophospholipid Metabolism in Bacteria gi|15607577 fig|83332.1.peg.437 CDS NC_000962 526080 525385 -3 - 696 Phosphatidylserine decarboxylase (EC 4.1.1.65) Glycerolipid and Glycerophospholipid Metabolism in Bacteria gi|15607578 fig|83332.1.peg.438 CDS NC_000962 527358 526141 -3 - 1218 Molybdopterin biosynthesis protein MoeA Involvement of a novel heat shock protein (Hsp22.5) in mycobacterial persistence;
Molybdenum cofactor biosynthesis gi|15607579 fig|83332.1.peg.439 CDS NC_000962 528312 527377 -3 - 936 probable oxidoreductase/Short-chain dehydrogenase - none - gi|15607580 fig|83332.1.peg.440 CDS NC_000962 528606 530228 3 + 1623 Heat shock protein 60 family chaperone GroEL GroEL GroES gi|15607581 fig|83332.1.peg.441 CDS NC_000962 530722 530294 -1 - 429 hypothetical protein - none - gi|15607582 fig|83332.1.peg.442 CDS NC_000962 532212 530749 -3 - 1464 PPE family protein - none - gi|15607583 fig|83332.1.peg.443 CDS NC_000962 532394 532909 2 + 516 hypothetical protein - none - gi|15607584 fig|83332.1.peg.444 CDS NC_000962 533787 533089 -3 - 699 FIG111991: hypothetical protein CBSS-313593.3.peg.2729 gi|15607585 fig|83332.1.peg.445 CDS NC_000962 534394 533831 -1 - 564 RNA polymerase sigma-70 factor CBSS-313593.3.peg.2729;
SigmaB stress responce regulation;
Transcription initiation, bacterial sigma factors gi|15607586 fig|83332.1.peg.446 CDS NC_000962 535213 534443 -1 - 771 FIG005069: Hypothetical protein CBSS-291331.3.peg.3674 gi|15607587 fig|83332.1.peg.447 CDS NC_000962 536505 535222 -3 - 1284 S-adenosyl-L-methionine dependent methyltransferase, similar to cyclopropane-fatty-acyl-phospholipid synthase CBSS-291331.3.peg.3674 gi|15607588 fig|83332.1.peg.448 CDS NC_000962 537167 536502 -2 - 666 FIG001571: Hypothetical protein CBSS-291331.3.peg.3674 gi|15607589 fig|83332.1.peg.449 CDS NC_000962 538546 537227 -1 - 1320 COG2907: Amine oxidase, flavin-containing - none - gi|15607590 fig|83332.1.peg.450 CDS NC_000962 541489 538586 -1 - 2904 Transmembrane transport protein MmpL4 - none - gi|15607591 fig|83332.1.peg.451 CDS NC_000962 541908 541486 -3 - 423 membrane protein, MmpS family - none - gi|15607592 fig|83332.1.peg.452 CDS NC_000962 542140 542850 1 + 711 Transcriptional regulator, TetR family - none - gi|15607593 fig|83332.1.peg.453 CDS NC_000962 543172 544728 1 + 1557 PPE family protein CBSS-164757.7.peg.5020 gi|15607594 fig|83332.1.peg.454 CDS NC_000962 544833 545183 3 + 351 hypothetical protein Rv0454 - none - gi|15607595 fig|83332.1.peg.455 CDS NC_000962 545819 545373 -2 - 447 Possible membrane protein - none - gi|15607596 fig|83332.1.peg.456 CDS NC_000962 546801 545887 -3 - 915 Enoyl-CoA hydratase (EC 4.2.1.17) Acetyl-CoA fermentation to Butyrate;
Fatty acid metabolism cluster gi|15607597 fig|83332.1.peg.457 CDS NC_000962 549605 547584 -2 - 2022 Prolyl endopeptidase (EC 3.4.21.26) - none - gi|15607598 fig|83332.1.peg.458 CDS NC_000962 549673 551196 1 + 1524 Aldehyde dehydrogenase (EC 1.2.1.3) Glycerolipid and Glycerophospholipid Metabolism in Bacteria;
Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate gi|15607599 fig|83332.1.peg.459 CDS NC_000962 551196 551687 3 + 492 FIG00821442: hypothetical protein - none - gi|15607600 fig|83332.1.peg.460 CDS NC_000962 551747 551986 2 + 240 Possible membrane protein - none - gi|15607601 fig|83332.1.peg.461 CDS NC_000962 552024 552548 3 + 525 Possible membrane protein - none - gi|15607602 fig|83332.1.peg.462 CDS NC_000962 552612 554006 3 + 1395 Dihydrolipoamide dehydrogenase (EC 1.8.1.4) 5-FCL-like protein;
Dehydrogenase complexes;
Glycine cleavage system;
Leucine Degradation and HMG-CoA Metabolism;
TCA Cycle gi|15607603 fig|83332.1.peg.463 CDS NC_000962 554014 554307 1 + 294 Possible membrane protein - none - gi|15607604 fig|83332.1.peg.464 CDS NC_000962 554883 554311 -3 - 573 hypothetical protein - none - gi|15607605 fig|83332.1.peg.465 CDS NC_000962 556304 554880 -2 - 1425 "Transcriptional regulator, XRE family" - none - gi|15607606 fig|83332.1.peg.466 CDS NC_000962 556456 557250 1 + 795 Acyl-ACP thioesterase - none - gi|15607607 fig|83332.1.peg.467 CDS NC_000962 557525 558811 2 + 1287 Isocitrate lyase (EC 4.1.3.1) / Methylisocitrate lyase (EC 4.1.3.30) Glyoxylate bypass;
Glyoxylate bypass cluster;
Methylcitrate cycle;
Propionate-CoA to Succinate Module;
Serine-glyoxylate cycle gi|15607608 fig|83332.1.peg.468 CDS NC_000962 558893 559753 2 + 861 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) Acetyl-CoA fermentation to Butyrate;
Acetyl-CoA fermentation to Butyrate;
Butanol Biosynthesis;
Fatty acid metabolism cluster;
Isoleucine degradation;
Polyhydroxybutyrate metabolism;
Polyhydroxybutyrate metabolism;
Valine degradation gi|15607609 fig|83332.1.peg.469 CDS NC_000962 559886 560746 2 + 861 POSSIBLE MYCOLIC ACID SYNTHASE UMAA1 - none - gi|15607610 fig|83332.1.peg.470 CDS NC_000962 561709 560846 -1 - 864 Mycolic acid synthase (PcaA/UmaA2) (Cyclopropane Synthase) - none - gi|15607611 fig|83332.1.peg.471 CDS NC_000962 562711 562223 -1 - 489 hypothetical protein Rv0471c - none - gi|15607612 fig|83332.1.peg.472 CDS NC_000962 563425 562721 -1 - 705 "Transcriptional regulator, TetR family" - none - gi|15607613 fig|83332.1.peg.473 CDS NC_000962 563562 564932 3 + 1371 Possible membrane protein - none - gi|15607614 fig|83332.1.peg.474 CDS NC_000962 565019 565441 2 + 423 XRE family transcriptional regulator SCO4198 - none - gi|15607615 fig|83332.1.peg.475 CDS NC_000962 565795 566394 1 + 600 Iron-regulated heparin binding hemagglutinin HbhA (Adhesin) - none - gi|15607616 fig|83332.1.peg.476 CDS NC_000962 566506 566769 1 + 264 FIG00820770: hypothetical membrane protein - none - gi|15607617 fig|83332.1.peg.477 CDS NC_000962 566774 567220 2 + 447 Possible membrane protein - none - gi|15607618 fig|83332.1.peg.478 CDS NC_000962 567220 567894 1 + 675 Deoxyribose-phosphate aldolase (EC 4.1.2.4) Deoxyribose and Deoxynucleoside Catabolism gi|15607619 fig|83332.1.peg.479 CDS NC_000962 568965 567919 -3 - 1047 Possible membrane protein - none - gi|15607620 fig|83332.1.peg.480 CDS NC_000962 569984 568962 -2 - 1023 Aliphatic amidase AmiE (EC 3.5.1.4) - none - gi|15607621 fig|83332.1.peg.481 CDS NC_000962 570510 569986 -3 - 525 hypothetical protein Rv0481c - none - gi|15607622 fig|83332.1.peg.482 CDS NC_000962 570537 571646 3 + 1110 UDP-N-acetylenolpyruvoylglucosamine reductase (EC 1.1.1.158) Peptidoglycan Biosynthesis;
UDP-N-acetylmuramate from Fructose-6-phosphate Biosynthesis gi|15607623 fig|83332.1.peg.483 CDS NC_000962 571708 573063 1 + 1356 Possible lipoprotein LprQ - none - gi|15607624 fig|83332.1.peg.484 CDS NC_000962 573799 573044 -1 - 756 Serine 3-dehydrogenase - none - gi|15607625 fig|83332.1.peg.485 CDS NC_000962 573982 575298 1 + 1317 Transcriptional regulatory protein - none - gi|15607626 fig|83332.1.peg.486 CDS NC_000962 575346 576788 3 + 1443 Glycosyltransferase MshA involved in mycothiol biosynthesis (EC 2.4.1.-) Glutathione analogs: mycothiol;
tRNA aminoacylation, Cys gi|15607627 fig|83332.1.peg.487 CDS NC_000962 576785 577336 2 + 552 Uncharacterized protein Rv0487/MT0505 clustered with mycothiol biosynthesis gene Glutathione analogs: mycothiol gi|15607628 fig|83332.1.peg.488 CDS NC_000962 577662 578267 3 + 606 Transporter, LysE family - none - gi|15607629 fig|83332.1.peg.489 CDS NC_000962 578424 579173 3 + 750 Phosphoglycerate mutase (EC 5.4.2.1) Glycolysis and Gluconeogenesis;
Phosphoglycerate mutase protein family gi|15607630 fig|83332.1.peg.490 CDS NC_000962 579347 580579 2 + 1233 Phosphate regulon sensor protein PhoR (SphS) (EC 2.7.13.3); Sensor-like histidine kinase senX3 (EC 2.7.13.3) High affinity phosphate transporter and control of PHO regulon;
PhoR-PhoB two-component regulatory system;
Phosphate metabolism gi|15607631 fig|83332.1.peg.491 CDS NC_000962 580807 581490 1 + 684 Phosphate regulon transcriptional regulatory protein PhoB (SphR); Sensory transduction protein regX3 High affinity phosphate transporter and control of PHO regulon;
PhoR-PhoB two-component regulatory system;
Phosphate metabolism gi|15607632 fig|83332.1.peg.492 CDS NC_000962 583541 581487 -2 - 2055 GMC-type oxidoreductase - none - gi|15607633 fig|83332.1.peg.493 CDS NC_000962 584688 583699 -3 - 990 hypothetical protein Rv0493c - none - gi|15607634 fig|83332.1.peg.494 CDS NC_000962 584672 585421 2 + 750 Transcriptional regulator, GntR family - none - gi|15607635 fig|83332.1.peg.495 CDS NC_000962 586312 585422 -1 - 891 FIG00820527: hypothetical protein - none - gi|15607636 fig|83332.1.peg.496 CDS NC_000962 586392 587378 3 + 987 Exopolyphosphatase (EC 3.6.1.11) High affinity phosphate transporter and control of PHO regulon;
Phosphate metabolism;
Polyphosphate gi|15607637 fig|83332.1.peg.497 CDS NC_000962 587375 588307 2 + 933 Possible membrane protein - none - gi|15607638 fig|83332.1.peg.498 CDS NC_000962 588323 589165 2 + 843 "AP endonuclease, family protein 2" - none - gi|15607639 fig|83332.1.peg.499 CDS NC_000962 589181 590056 2 + 876 TesB-like acyl-CoA thioesterase 3 Acyl-CoA thioesterase II gi|15607640 fig|83332.1.peg.500 CDS NC_000962 590081 590968 2 + 888 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) A Hypothetical Protein Related to Proline Metabolism;
Proline, 4-hydroxyproline uptake and utilization;
Proline Synthesis gi|15607641 fig|83332.1.peg.501 CDS NC_000962 591652 592782 1 + 1131 UDP-glucose 4-epimerase (EC 5.1.3.2) - none - gi|15607642 fig|83332.1.peg.502 CDS NC_000962 592789 593865 1 + 1077 Phospholipid/glycerol acyltransferase - none - gi|15607643 fig|83332.1.peg.503 CDS NC_000962 594777 593869 -3 - 909 Cyclopropane-fatty-acyl-phospholipid synthase 2, CmaA2 (EC 2.1.1.79) - none - gi|15607644 fig|83332.1.peg.504 CDS NC_000962 595300 594800 -1 - 501 (3R)-hydroxyacyl-ACP dehydratase subunit HadA - none - gi|15607645 fig|83332.1.peg.505 CDS NC_000962 596583 595462 -3 - 1122 Phosphoserine phosphatase (EC 3.1.3.3) CBSS-336982.3.peg.3874;
Glycine and Serine Utilization;
Serine Biosynthesis gi|15607646 fig|83332.1.peg.506 CDS NC_000962 596757 597200 3 + 444 membrane protein, MmpS family - none - gi|15607647 fig|83332.1.peg.507 CDS NC_000962 597197 600103 2 + 2907 Possible membrane protein - none - gi|15607648 fig|83332.1.peg.508 CDS NC_000962 600096 600389 3 + 294 hypothetical protein Rv0508 - none - gi|15607649 fig|83332.1.peg.509 CDS NC_000962 600439 601845 1 + 1407 Glutamyl-tRNA reductase (EC 1.2.1.70) Heme and Siroheme Biosynthesis gi|15607650 fig|83332.1.peg.510 CDS NC_000962 601855 602784 1 + 930 Porphobilinogen deaminase (EC 2.5.1.61) Heme and Siroheme Biosynthesis gi|15607651 fig|83332.1.peg.511 CDS NC_000962 602817 604514 3 + 1698 Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75) Coenzyme B12 biosynthesis;
Heme and Siroheme Biosynthesis;
Heme and Siroheme Biosynthesis gi|15607652 fig|83332.1.peg.512 CDS NC_000962 604600 605589 1 + 990 Porphobilinogen synthase (EC 4.2.1.24) Heme and Siroheme Biosynthesis gi|15607653 fig|83332.1.peg.513 CDS NC_000962 605602 606150 1 + 549 Transmembrane transport protein MmpL2 - none - gi|15607654 fig|83332.1.peg.514 CDS NC_000962 606147 606446 3 + 300 Possible membrane protein - none - gi|15607655 fig|83332.1.peg.515 CDS NC_000962 606549 608060 3 + 1512 13E12 repeat family protein - none - gi|15607656 fig|83332.1.peg.516 CDS NC_000962 608533 608057 -1 - 477 FIG00507771: hypothetical protein - none - gi|15607657 fig|83332.1.peg.517 CDS NC_000962 608744 610054 2 + 1311 Membrane acyltransferase - none - gi|15607658 fig|83332.1.peg.518 CDS NC_000962 610186 610881 1 + 696 Possible membrane protein - none - gi|15607659 fig|83332.1.peg.519 CDS NC_000962 612072 611170 -3 - 903 Possible membrane protein - none - gi|15607660 fig|83332.1.peg.520 CDS NC_000962 612253 612603 1 + 351 Similar to methyltransferase domain of sarcosine-dimethylglycine methyltransferase - none - gi|15607661 fig|83332.1.peg.521 CDS NC_000962 612931 612563 -1 - 369 hypothetical protein Rv0521c - none - gi|15607662 fig|83332.1.peg.522 CDS NC_000962 613036 614340 1 + 1305 Aromatic amino acid transport protein AroP Aromatic amino acid degradation gi|15611061 fig|83332.1.peg.523 CDS NC_000962 614719 614324 -1 - 396 hypothetical protein Rv0523c - none - gi|15607663 fig|83332.1.peg.524 CDS NC_000962 614833 616221 1 + 1389 Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8) CBSS-196164.1.peg.461;
Heme and Siroheme Biosynthesis gi|15607664 fig|83332.1.peg.525 CDS NC_000962 616221 616829 3 + 609 Hypothetical, related to broad specificity phosphatases COG0406 CBSS-196164.1.peg.461 gi|15607665 fig|83332.1.peg.526 CDS NC_000962 616844 617494 2 + 651 Thiol:disulfide oxidoreductase related to ResA Biogenesis of c-type cytochromes;
CBSS-196164.1.peg.461 gi|15607666 fig|83332.1.peg.527 CDS NC_000962 617491 618270 1 + 780 Cytochrome c-type biogenesis protein CcdA (DsbD analog) Biogenesis of c-type cytochromes;
CBSS-196164.1.peg.461;
Peptide methionine sulfoxide reductase;
Periplasmic disulfide interchange gi|15607667 fig|83332.1.peg.528 CDS NC_000962 618303 619892 3 + 1590 Ccs1/ResB-related putative cytochrome C-type biogenesis protein Biogenesis of c-type cytochromes;
CBSS-196164.1.peg.461 gi|15607668 fig|83332.1.peg.529 CDS NC_000962 619889 620863 2 + 975 Cytochrome c-type biogenesis protein CcsA/ResC Biogenesis of c-type cytochromes;
CBSS-196164.1.peg.461 gi|15607669 fig|83332.1.peg.530 CDS NC_000962 620905 622122 1 + 1218 Chromosome partitioning ATPase - none - gi|15607670 fig|83332.1.peg.531 CDS NC_000962 622327 622644 1 + 318 Possible membrane protein - none - gi|15607671 fig|83332.1.peg.532 CDS NC_000962 622791 624575 3 + 1785 PE-PGRS family protein PPE gene cluster in Mycobacteria gi|15607672 fig|83332.1.peg.533 CDS NC_000962 625478 624471 -2 - 1008 "3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.41)" - none - gi|15607673 fig|83332.1.peg.534 CDS NC_000962 626438 625560 -2 - 879 1,4-dihydroxy-2-naphthoate polyprenyltransferase (EC 2.5.1.74) Menaquinone and Phylloquinone Biosynthesis;
Menaquinone and Phylloquinone Biosynthesis -- gjo gi|15607674 fig|83332.1.peg.535 CDS NC_000962 626455 627249 1 + 795 5'-methylthioadenosine phosphorylase (EC 2.4.2.28) - none - gi|15607675 fig|83332.1.peg.536 CDS NC_000962 627246 628286 3 + 1041 UDP-glucose 4-epimerase (EC 5.1.3.2) Lactose and Galactose Uptake and Utilization;
Rhamnose containing glycans gi|15607676 fig|83332.1.peg.537 CDS NC_000962 629729 628296 -2 - 1434 Possible membrane protein - none - gi|15607677 fig|83332.1.peg.538 CDS NC_000962 630038 631684 2 + 1647 Possible membrane protein - none - gi|15607678 fig|83332.1.peg.539 CDS NC_000962 631741 632373 1 + 633 Glycosyltransferase (EC 2.4.1.-) - none - gi|15607679 fig|83332.1.peg.540 CDS NC_000962 632370 633032 3 + 663 FIG00821404: hypothetical protein - none - gi|15607680 fig|83332.1.peg.541 CDS NC_000962 634402 633053 -1 - 1350 Possible membrane protein - none - gi|15607681 fig|83332.1.peg.542 CDS NC_000962 635502 634414 -3 - 1089 O-succinylbenzoic acid--CoA ligase (EC 6.2.1.26) Menaquinone and Phylloquinone Biosynthesis;
Menaquinone and Phylloquinone Biosynthesis -- gjo;
Muconate lactonizing enzyme family gi|15607682 fig|83332.1.peg.543 CDS NC_000962 635873 635571 -2 - 303 hypothetical protein Rv0543c - none - gi|15607683 fig|83332.1.peg.544 CDS NC_000962 636211 635933 -1 - 279 Possible membrane protein - none - gi|15607684 fig|83332.1.peg.545 CDS NC_000962 637461 636208 -3 - 1254 Probable low-affinity inorganic phosphate transporter Phosphate metabolism gi|15607685 fig|83332.1.peg.546 CDS NC_000962 637967 637581 -2 - 387 FIG020377: hypothetical protein - none - gi|15607686 fig|83332.1.peg.547 CDS NC_000962 638914 638030 -1 - 885 Oxidoreductase, short-chain dehydrogenase/reductase family - none - gi|15607687 fig|83332.1.peg.548 CDS NC_000962 639954 639010 -3 - 945 Naphthoate synthase (EC 4.1.3.36) Menaquinone and Phylloquinone Biosynthesis;
Menaquinone and Phylloquinone Biosynthesis -- gjo gi|15607688 fig|83332.1.peg.549 CDS NC_000962 640639 640226 -1 - 414 Toxin 1, PIN domain Toxin-Antitoxin MT1 gi|15607689 fig|83332.1.peg.550 CDS NC_000962 640902 640636 -3 - 267 Antitoxin 1a Toxin-Antitoxin MT1 gi|15607690 fig|83332.1.peg.551 CDS NC_000962 642809 641094 -2 - 1716 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) Biotin synthesis cluster;
Fatty acid metabolism cluster gi|15607691 fig|83332.1.peg.552 CDS NC_000962 642887 644491 2 + 1605 Exoenzymes regulatory protein AepA precursor - none - gi|15607692 fig|83332.1.peg.553 CDS NC_000962 644488 645468 1 + 981 O-succinylbenzoate synthase (EC 4.2.1.113) Muconate lactonizing enzyme family gi|15607693 fig|83332.1.peg.554 CDS NC_000962 645465 646253 3 + 789 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (EC 4.2.99.20) Menaquinone and Phylloquinone Biosynthesis;
Menaquinone and Phylloquinone Biosynthesis -- gjo;
Muconate lactonizing enzyme family gi|15607694 fig|83332.1.peg.555 CDS NC_000962 646296 647960 3 + 1665 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase (EC 2.2.1.9) Menaquinone and Phylloquinone Biosynthesis;
Menaquinone and Phylloquinone Biosynthesis -- gjo gi|15607695 fig|83332.1.peg.556 CDS NC_000962 647957 648472 2 + 516 Possible membrane protein - none - gi|15607696 fig|83332.1.peg.557 CDS NC_000962 648534 649670 3 + 1137 Mannosyltransferase PimB - none - gi|15607697 fig|83332.1.peg.558 CDS NC_000962 649687 650391 1 + 705 Ubiquinone/menaquinone biosynthesis methyltransferase UbiE (EC 2.1.1.-) Menaquinone and Phylloquinone Biosynthesis;
Menaquinone and Phylloquinone Biosynthesis -- gjo;
Ubiquinone Biosynthesis gi|15607698 fig|83332.1.peg.559 CDS NC_000962 650743 650405 -1 - 339 POSSIBLE CONSERVED SECRETED PROTEIN - none - gi|15607699 fig|83332.1.peg.560 CDS NC_000962 651502 650777 -1 - 726 Possible benzoquinone methyltransferase - none - gi|15607700 fig|83332.1.peg.561 CDS NC_000962 652753 651527 -1 - 1227 Possible oxidoreductase (EC 1.-.-.-) - none - gi|15607701 fig|83332.1.peg.562 CDS NC_000962 652769 653776 2 + 1008 Octaprenyl diphosphate synthase (EC 2.5.1.90) / Dimethylallyltransferase (EC 2.5.1.1) / (2E,6E)-farnesyl diphosphate synthase (EC 2.5.1.10) / Geranylgeranyl diphosphate synthase (EC 2.5.1.29) Carotenoids;
Carotenoids;
Isoprenoid Biosynthesis;
Isoprenoid Biosynthesis;
Isoprenoid Biosynthesis: Interconversions;
Isoprenoinds for Quinones;
Isoprenoinds for Quinones;
Isoprenoinds for Quinones;
Isoprenoinds for Quinones;
Polyprenyl Diphosphate Biosynthesis;
Polyprenyl Diphosphate Biosynthesis;
Polyprenyl Diphosphate Biosynthesis gi|15607702 fig|83332.1.peg.563 CDS NC_000962 653877 654737 3 + 861 Probable protease htpX homolog (EC 3.4.24.-) - none - gi|15607703 fig|83332.1.peg.564 CDS NC_000962 655947 654922 -3 - 1026 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) Glutaredoxins;
Glycerol and Glycerol-3-phosphate Uptake and Utilization;
Glycerolipid and Glycerophospholipid Metabolism in Bacteria gi|15607704 fig|83332.1.peg.565 CDS NC_000962 657468 656008 -3 - 1461 "Monooxygenase, flavin-binding family" - none - gi|15607705 fig|83332.1.peg.566 CDS NC_000962 658037 657546 -2 - 492 FIG001943: hypothetical protein YajQ Broadly distributed proteins not in subsystems gi|15607706 fig|83332.1.peg.567 CDS NC_000962 658319 659338 2 + 1020 O-methyltransferase - none - gi|15607707 fig|83332.1.peg.568 CDS NC_000962 659448 660866 3 + 1419 Cytochrome P450 135B1 - none - gi|15607708 fig|83332.1.peg.569 CDS NC_000962 661001 661267 2 + 267 hypothetical protein Rv0569 - none - gi|15607709 fig|83332.1.peg.570 CDS NC_000962 661293 663371 3 + 2079 Ribonucleotide reductase of class II (coenzyme B12-dependent) (EC 1.17.4.1) Inteins;
Ribonucleotide reduction gi|15607710 fig|83332.1.peg.571 CDS NC_000962 664816 663485 -1 - 1332 Phosphoribosyl transferase domain protein - none - gi|15607711 fig|83332.1.peg.572 CDS NC_000962 665381 665040 -2 - 342 hypothetical protein Rv0572c - none - gi|15607712 fig|83332.1.peg.573 CDS NC_000962 667240 665849 -1 - 1392 Nicotinate phosphoribosyltransferase (EC 2.4.2.11) NAD and NADP cofactor biosynthesis global;
Redox-dependent regulation of nucleus processes gi|15607713 fig|83332.1.peg.574 CDS NC_000962 668392 667250 -1 - 1143 Capsule biosynthesis protein CapA - none - gi|15607714 fig|83332.1.peg.575 CDS NC_000962 669743 668577 -2 - 1167 Oxidoreductase - none - gi|15607715 fig|83332.1.peg.576 CDS NC_000962 669846 671150 3 + 1305 Transcriptional regulator, ArsR family cAMP signaling in bacteria gi|15607716 fig|83332.1.peg.577 CDS NC_000962 671164 671949 1 + 786 27 kDa antigen Cfp30B - none - gi|15607717 fig|83332.1.peg.578 CDS NC_000962 675914 671994 -2 - 3921 PE-PGRS family protein PPE gene cluster in Mycobacteria gi|15607718 fig|83332.1.peg.579 CDS NC_000962 676236 676994 3 + 759 FIG00825218: hypothetical protein - none - gi|15607719 fig|83332.1.peg.580 CDS NC_000962 677614 677123 -1 - 492 FIG030357: hypothetical protein - none - gi|15607720 fig|83332.1.peg.581 CDS NC_000962 677708 677923 2 + 216 hypothetical protein Rv0581 - none - gi|15607721 fig|83332.1.peg.582 CDS NC_000962 677920 678327 1 + 408 hypothetical protein Rv0582 - none - gi|15607722 fig|83332.1.peg.583 CDS NC_000962 679073 678387 -2 - 687 Lipoprotein LpqN - none - gi|15607723 fig|83332.1.peg.584 CDS NC_000962 679227 681860 3 + 2634 Alpha-1,2-mannosidase Mannose Metabolism gi|15607724 fig|83332.1.peg.585 CDS NC_000962 684270 681883 -3 - 2388 Possible membrane protein - none - gi|15607725 fig|83332.1.peg.586 CDS NC_000962 684408 685130 3 + 723 Transcriptional regulator, GntR family - none - gi|15607726 fig|83332.1.peg.587 CDS NC_000962 685127 685924 2 + 798 Conserved hypothetical integral membrane protein YrbE1A Mycobacterium virulence operon MCE involved in cell invasion gi|15607727 fig|83332.1.peg.588 CDS NC_000962 685926 686813 3 + 888 Conserved hypothetical integral membrane protein YrbE1B Mycobacterium virulence operon MCE involved in cell invasion gi|15607728 fig|83332.1.peg.589 CDS NC_000962 686819 688033 2 + 1215 MCE-family protein Mce1A Mycobacterium virulence operon MCE involved in cell invasion gi|15607729 fig|83332.1.peg.590 CDS NC_000962 688030 688857 1 + 828 MCE-family protein Mce1B Mycobacterium virulence operon MCE involved in cell invasion gi|15607730 fig|83332.1.peg.591 CDS NC_000962 689057 690502 2 + 1446 MCE-family protein Mce1C Mycobacterium virulence operon MCE involved in cell invasion gi|15607731 fig|83332.1.peg.592 CDS NC_000962 690499 692025 1 + 1527 MCE-family protein Mce1D Mycobacterium virulence operon MCE involved in cell invasion gi|15607732 fig|83332.1.peg.593 CDS NC_000962 692022 693230 3 + 1209 MCE-family lipoprotein LprK (MCE-family lipoprotein Mce1e) Mycobacterium virulence operon MCE involved in cell invasion gi|15607733 fig|83332.1.peg.594 CDS NC_000962 693235 694785 1 + 1551 MCE-family protein Mce1F Mycobacterium virulence operon MCE involved in cell invasion gi|15607734 fig|83332.1.peg.595 CDS NC_000962 695229 694837 -3 - 393 hypothetical protein Rv0595c - none - gi|15607735 fig|83332.1.peg.596 CDS NC_000962 695483 695226 -2 - 258 FIG044579: hypothetical protein - none - gi|15607736 fig|83332.1.peg.597 CDS NC_000962 696901 695666 -1 - 1236 ATPase - none - gi|15607737 fig|83332.1.peg.598 CDS NC_000962 697565 697152 -2 - 414 Toxin 1, PIN domain Toxin-Antitoxin MT1 gi|15607738 fig|83332.1.peg.599 CDS NC_000962 697798 697562 -1 - 237 hypothetical protein Rv0599c - none - gi|15607739 fig|83332.1.peg.600 CDS NC_000962 698525 697902 -2 - 624 hypothetical protein Rv0600c - none - gi|15607740 fig|83332.1.peg.601 CDS NC_000962 698992 698522 -1 - 471 hypothetical protein Rv0601c - none - gi|15607741 fig|83332.1.peg.602 CDS NC_000962 699797 699036 -2 - 762 (MTCY19H5.20), len: 232, two-component response regulator, almost identical to EM_BA:MTU56083 U56083 Mycobacterium tuberculosis two component response regulator (tcrA) gene, TRQ50825, (234 aa) opt: 1528, E(): 0, (97.9% identity in 234 aa overlap). Also similar to many other M. tuberculosis two-component regulators eg. MTCY10G2.16 (47.4% identity in 232 aa overlap) - none - gi|15607742 fig|83332.1.peg.603 CDS NC_000962 699854 700165 2 + 312 hypothetical protein Rv0603 - none - gi|15607743 fig|83332.1.peg.604 CDS NC_000962 700237 701187 1 + 951 PROBABLE CONSERVED LIPOPROTEIN LPQO - none - gi|15607744 fig|83332.1.peg.605 CDS NC_000962 701404 702012 1 + 609 hypothetical protein Rv0605 - none - gi|15607745 fig|83332.1.peg.606 CDS NC_000962 702014 702757 2 + 744 hypothetical protein Rv0606 - none - gi|15607746 fig|83332.1.peg.607 CDS NC_000962 702811 703197 1 + 387 hypothetical protein Rv0607 - none - gi|15607747 fig|83332.1.peg.608 CDS NC_000962 703242 703487 3 + 246 hypothetical protein Rv0608 - none - gi|15607748 fig|83332.1.peg.609 CDS NC_000962 703484 703885 2 + 402 hypothetical protein Rv0609 - none - gi|15607749 fig|83332.1.peg.610 CDS NC_000962 705907 704750 -1 - 1158 hypothetical protein Rv0610c - none - gi|15607750 fig|83332.1.peg.611 CDS NC_000962 706342 705959 -1 - 384 hypothetical protein Rv0611c - none - gi|15607751 fig|83332.1.peg.612 CDS NC_000962 706322 706927 2 + 606 hypothetical protein Rv0612 - none - gi|15607752 fig|83332.1.peg.613 CDS NC_000962 709513 706946 -1 - 2568 hypothetical protein Rv0613c - none - gi|15607753 fig|83332.1.peg.614 CDS NC_000962 709354 710346 1 + 993 Possible membrane protein - none - gi|15607754 fig|83332.1.peg.615 CDS NC_000962 710343 710585 3 + 243 Possible membrane protein - none - gi|15607755 fig|83332.1.peg.616 CDS NC_000962 710848 710582 -1 - 267 hypothetical protein - none - gi|15607756 fig|83332.1.peg.617 CDS NC_000962 711004 711405 1 + 402 FIG037359: hypothetical protein - none - gi|15607757 fig|83332.1.peg.618 CDS NC_000962 711534 712229 3 + 696 Galactose-1-phosphate uridylyltransferase (EC 2.7.7.10) Lactose and Galactose Uptake and Utilization gi|15607758 fig|83332.1.peg.619 CDS NC_000962 712172 712717 2 + 546 Galactose-1-phosphate uridylyltransferase (EC 2.7.7.10) Lactose and Galactose Uptake and Utilization gi|15607759 fig|83332.1.peg.620 CDS NC_000962 712714 713805 1 + 1092 Galactokinase (EC 2.7.1.6) Lactose and Galactose Uptake and Utilization gi|15607760 fig|83332.1.peg.621 CDS NC_000962 714200 715264 2 + 1065 Possible membrane protein - none - gi|15607761 fig|83332.1.peg.622 CDS NC_000962 715290 716315 3 + 1026 Possible membrane protein - none - gi|15607762 fig|83332.1.peg.623 CDS NC_000962 716408 716662 2 + 255 hypothetical protein Rv0623 - none - gi|15607763 fig|83332.1.peg.624 CDS NC_000962 716662 717057 1 + 396 FIG00825799: hypothetical protein - none - gi|15607764 fig|83332.1.peg.625 CDS NC_000962 717891 717151 -3 - 741 Possible membrane protein - none - gi|15607765 fig|83332.1.peg.626 CDS NC_000962 718023 718283 3 + 261 hypothetical protein Rv0626 - none - gi|15607766 fig|83332.1.peg.627 CDS NC_000962 718280 718687 2 + 408 hypothetical protein Rv0627 - none - gi|15607767 fig|83332.1.peg.628 CDS NC_000962 719910 718759 -3 - 1152 FIG00822946: hypothetical protein - none - gi|15607768 fig|83332.1.peg.629 CDS NC_000962 721730 720003 -2 - 1728 Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) ## RecD DNA repair, bacterial RecBCD pathway gi|15607769 fig|83332.1.peg.630 CDS NC_000962 725011 721727 -1 - 3285 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) ## RecB DNA repair, bacterial RecBCD pathway gi|15607770 fig|83332.1.peg.631 CDS NC_000962 728304 725011 -3 - 3294 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) ## RecC DNA repair, bacterial RecBCD pathway gi|15607771 fig|83332.1.peg.632 CDS NC_000962 729276 728581 -3 - 696 Enoyl-CoA hydratase (EC 4.2.1.17) - none - gi|15607772 fig|83332.1.peg.633 CDS NC_000962 730164 729325 -3 - 840 Possible membrane protein - none - gi|15607773 fig|83332.1.peg.634 CDS NC_000962 731031 730318 -3 - 714 hypothetical protein - none - gi|15607774 fig|83332.1.peg.635 CDS NC_000962 731928 732404 3 + 477 hypothetical protein Rv0635 - none - gi|15607775 fig|83332.1.peg.636 CDS NC_000962 732391 732819 1 + 429 (3R)-hydroxyacyl-ACP dehydratase subunit HadB - none - gi|15607776 fig|83332.1.peg.637 CDS NC_000962 732823 733323 1 + 501 hypothetical protein Rv0637 - none - gi|15607777 fig|83332.1.peg.638 CDS NC_000962 733735 734220 1 + 486 Preprotein translocase subunit SecE (TC 3.A.5.1.1) LSU ribosomal proteins cluster gi|15607778 fig|83332.1.peg.639 CDS NC_000962 734252 734968 2 + 717 Transcription antitermination protein NusG LSU ribosomal proteins cluster;
Transcription factors bacterial gi|15607779 fig|83332.1.peg.640 CDS NC_000962 735020 735448 2 + 429 LSU ribosomal protein L11p (L12e) LSU ribosomal proteins cluster;
Ribosome LSU bacterial gi|15607780 fig|83332.1.peg.641 CDS NC_000962 735515 736222 2 + 708 LSU ribosomal protein L1p (L10Ae) LSU ribosomal proteins cluster;
Ribosome LSU bacterial gi|15607781 fig|83332.1.peg.642 CDS NC_000962 737201 736296 -2 - 906 METHOXY MYCOLIC ACID SYNTHASE 4 MMAA4 (METHYL MYCOLIC ACID SYNTHASE 4) (MMA4) (HYDROXY MYCOLIC ACID SYNTHASE) - none - gi|15607782 fig|83332.1.peg.643 CDS NC_000962 738147 737266 -3 - 882 METHOXY MYCOLIC ACID SYNTHASE 3 MMAA3 (METHYL MYCOLIC ACID SYNTHASE 3) (MMA3) (HYDROXY MYCOLIC ACID SYNTHASE) - none - gi|15607783 fig|83332.1.peg.644 CDS NC_000962 739158 738295 -3 - 864 METHOXY MYCOLIC ACID SYNTHASE 2 MMAA2 (METHYL MYCOLIC ACID SYNTHASE 2) (MMA2) (HYDROXY MYCOLIC ACID SYNTHASE) - none - gi|15607784 fig|83332.1.peg.645 CDS NC_000962 740185 739325 -1 - 861 Methoxy mycolic acid synthase 1 MmaA1 (EC 2.1.1.-) - none - gi|15607785 fig|83332.1.peg.646 CDS NC_000962 741137 740232 -2 - 906 Carboxyl esterase - none - gi|15607786 fig|83332.1.peg.647 CDS NC_000962 742615 741149 -1 - 1467 ABC1 family protein ## group 22 - none - gi|15607787 fig|83332.1.peg.648 CDS NC_000962 742717 746364 1 + 3648 Alpha-mannosidase (EC 3.2.1.24) - none - gi|15607788 fig|83332.1.peg.649 CDS NC_000962 746361 747035 3 + 675 Malonyl CoA-acyl carrier protein transacylase FabD2 - none - gi|15607789 fig|83332.1.peg.650 CDS NC_000962 747035 747943 2 + 909 Sugar kinase - none - gi|15607790 fig|83332.1.peg.651 CDS NC_000962 748274 748810 2 + 537 LSU ribosomal protein L10p (P0) LSU ribosomal proteins cluster;
Ribosome LSU bacterial gi|15607791 fig|83332.1.peg.652 CDS NC_000962 748847 749239 2 + 393 LSU ribosomal protein L7/L12 (P1/P2) LSU ribosomal proteins cluster;
Ribosome LSU bacterial gi|15607792 fig|83332.1.peg.653 CDS NC_000962 749927 749232 -2 - 696 Transcriptional regulator, TetR family - none - gi|15607793 fig|83332.1.peg.654 CDS NC_000962 749998 751503 1 + 1506 "Lignostilbene-alpha,beta-dioxygenase and related enzymes" - none - gi|15607794 fig|83332.1.peg.655 CDS NC_000962 751515 752594 3 + 1080 Probable ribonucleotide transport ATP-binding protein mkl - none - gi|15607795 fig|83332.1.peg.656 CDS NC_000962 753365 752982 -2 - 384 hypothetical protein Rv0656c - none - gi|15607796 fig|83332.1.peg.657 CDS NC_000962 753615 753460 -3 - 156 hypothetical protein Rv0657c - none - gi|15607797 fig|83332.1.peg.658 CDS NC_000962 754407 753691 -3 - 717 Possible membrane protein - none - gi|15607798 fig|83332.1.peg.659 CDS NC_000962 754991 754683 -2 - 309 Death on curing protein, Doc toxin Phd-Doc, YdcE-YdcD toxin-antitoxin (programmed cell death) systems gi|15607799 fig|83332.1.peg.660 CDS NC_000962 755223 754978 -3 - 246 Prevent host death protein, Phd antitoxin Phd-Doc, YdcE-YdcD toxin-antitoxin (programmed cell death) systems gi|15607800 fig|83332.1.peg.661 CDS NC_000962 755770 755333 -1 - 438 hypothetical protein Rv0661c - none - gi|15607801 fig|83332.1.peg.662 CDS NC_000962 756135 755767 -3 - 369 "DNA-binding protein, CopG family" - none - gi|15607802 fig|83332.1.peg.663 CDS NC_000962 756135 758498 3 + 2364 Arylsulfatase (EC 3.1.6.1) Sulfatases and sulfatase modifying factor 1 gi|15607803 fig|83332.1.peg.664 CDS NC_000962 758530 758802 1 + 273 FIG090692: hypothetical protein, Rv0664 - none - gi|15607804 fig|83332.1.peg.665 CDS NC_000962 758799 759137 3 + 339 FIG056034: hypothetical protein, Rv0665 - none - gi|15607805 fig|83332.1.peg.666 CDS NC_000962 759134 759307 2 + 174 FIG108202: hypothetical protein Mycobacterium virulence operon involved in DNA transcription gi|15607806 fig|83332.1.peg.667 CDS NC_000962 759805 763323 1 + 3519 DNA-directed RNA polymerase beta subunit (EC 2.7.7.6) Mycobacterium virulence operon involved in DNA transcription;
RNA polymerase bacterial gi|15607807 fig|83332.1.peg.668 CDS NC_000962 763368 767318 3 + 3951 DNA-directed RNA polymerase beta' subunit (EC 2.7.7.6) Mycobacterium virulence operon involved in DNA transcription;
RNA polymerase bacterial gi|15607808 fig|83332.1.peg.669 CDS NC_000962 769595 767682 -2 - 1914 Alkaline ceramidase - none - gi|15607809 fig|83332.1.peg.670 CDS NC_000962 769790 770548 2 + 759 Endonuclease IV (EC 3.1.21.2) DNA repair, bacterial gi|15607810 fig|83332.1.peg.671 CDS NC_000962 770580 771422 3 + 843 Lipoprotein LpqP - none - gi|15607811 fig|83332.1.peg.672 CDS NC_000962 771482 773110 2 + 1629 Acyl-CoA dehydrogenase (EC 1.3.8.7) - none - gi|15607812 fig|83332.1.peg.673 CDS NC_000962 773121 774059 3 + 939 Enoyl-CoA hydratase - none - gi|15607813 fig|83332.1.peg.674 CDS NC_000962 774062 774784 2 + 723 Phenylacetic acid degradation operon negative regulatory protein PaaX - none - gi|15607814 fig|83332.1.peg.675 CDS NC_000962 774781 775572 1 + 792 Enoyl-CoA hydratase (EC 4.2.1.17) Acetyl-CoA fermentation to Butyrate;
Fatty acid metabolism cluster gi|15607815 fig|83332.1.peg.676 CDS NC_000962 778478 775584 -2 - 2895 Transmembrane transport protein MmpL5 - none - gi|15607816 fig|83332.1.peg.677 CDS NC_000962 778903 778475 -1 - 429 membrane protein, MmpS family - none - gi|15607817 fig|83332.1.peg.678 CDS NC_000962 778988 779485 2 + 498 hypothetical protein - none - gi|15607818 fig|83332.1.peg.679 CDS NC_000962 780038 779541 -2 - 498 hypothetical protein - none - gi|15607819 fig|83332.1.peg.680 CDS NC_000962 780414 780040 -3 - 375 Possible membrane protein - none - gi|15607820 fig|83332.1.peg.681 CDS NC_000962 780719 781309 2 + 591 Transcriptional regulator, TetR family - none - gi|15607821 fig|83332.1.peg.682 CDS NC_000962 781558 781932 1 + 375 SSU ribosomal protein S12p (S23e) Mycobacterium virulence operon involved in protein synthesis (SSU ribosomal proteins);
Ribosome SSU bacterial gi|15607822 fig|83332.1.peg.683 CDS NC_000962 781932 782402 3 + 471 SSU ribosomal protein S7p (S5e) Mycobacterium virulence operon involved in protein synthesis (SSU ribosomal proteins);
Ribosome SSU bacterial gi|15607823 fig|83332.1.peg.684 CDS NC_000962 782483 784588 2 + 2106 Translation elongation factor G Mycobacterium virulence operon involved in protein synthesis (SSU ribosomal proteins);
Translation elongation factor G family;
Translation elongation factors bacterial;
Universal GTPases gi|15607824 fig|83332.1.peg.685 CDS NC_000962 784819 786009 1 + 1191 Translation elongation factor Tu Mycobacterium virulence operon involved in protein synthesis (SSU ribosomal proteins);
Translation elongation factors bacterial;
Universal GTPases gi|15607825 fig|83332.1.peg.686 CDS NC_000962 786147 786944 3 + 798 FIG025093: Probable membrane protein Mycobacterium virulence operon involved in protein synthesis (SSU ribosomal proteins) gi|15607826 fig|83332.1.peg.687 CDS NC_000962 787097 787924 2 + 828 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) - none - gi|15607827 fig|83332.1.peg.688 CDS NC_000962 787938 789158 3 + 1221 Ferredoxin reductase Anaerobic respiratory reductases gi|15607828 fig|83332.1.peg.689 CDS NC_000962 789409 789155 -1 - 255 hypothetical protein - none - gi|15607829 fig|83332.1.peg.690 CDS NC_000962 791071 790022 -1 - 1050 hypothetical protein Rv0690c - none - gi|15607830 fig|83332.1.peg.691 CDS NC_000962 791664 791068 -3 - 597 Mycofactocin system transcriptional regulator Mycofactocin system cluster gi|15607831 fig|83332.1.peg.692 CDS NC_000962 791829 792158 3 + 330 Mycofactocin system small protein Mycofactocin system cluster gi|15607832 fig|83332.1.peg.693 CDS NC_000962 792155 793330 2 + 1176 Mycofactocin radical SAM maturase Mycofactocin system cluster gi|15607833 fig|83332.1.peg.694 CDS NC_000962 793333 794523 1 + 1191 Mycofactocin system heme/flavin dehydrogenase Mycofactocin system cluster gi|15607834 fig|83332.1.peg.695 CDS NC_000962 794713 795468 1 + 756 Cyclic amid hydrolase in mycofactocin cluster Mycofactocin system cluster gi|15607835 fig|83332.1.peg.696 CDS NC_000962 795517 796929 1 + 1413 Mycofactocin system glycosyltransferase Mycofactocin system cluster gi|15607836 fig|83332.1.peg.697 CDS NC_000962 796931 798370 2 + 1440 Dehydrogenase in mycofactocin cluster Mycofactocin system cluster gi|15607837 fig|83332.1.peg.698 CDS NC_000962 798831 799442 3 + 612 hypothetical protein Rv0698 - none - gi|15607838 fig|83332.1.peg.699 CDS NC_000962 799627 799848 1 + 222 hypothetical protein Rv0699 - none - gi|15607839 fig|83332.1.peg.700 CDS NC_000962 800485 800790 1 + 306 SSU ribosomal protein S10p (S20e) Ribosome SSU bacterial gi|15607840 fig|83332.1.peg.701 CDS NC_000962 800807 801460 2 + 654 LSU ribosomal protein L3p (L3e) Ribosome LSU bacterial gi|15607841 fig|83332.1.peg.702 CDS NC_000962 801460 802131 1 + 672 LSU ribosomal protein L4p (L1e) Ribosome LSU bacterial gi|15607842 fig|83332.1.peg.703 CDS NC_000962 802131 802433 3 + 303 LSU ribosomal protein L23p (L23Ae) Ribosome LSU bacterial gi|15607843 fig|83332.1.peg.704 CDS NC_000962 802526 803368 2 + 843 LSU ribosomal protein L2p (L8e) Ribosome LSU bacterial gi|15607844 fig|83332.1.peg.705 CDS NC_000962 803409 803690 3 + 282 SSU ribosomal protein S19p (S15e) Ribosome SSU bacterial gi|15607845 fig|83332.1.peg.706 CDS NC_000962 803687 804280 2 + 594 LSU ribosomal protein L22p (L17e) Ribosome LSU bacterial gi|15607846 fig|83332.1.peg.707 CDS NC_000962 804280 805104 1 + 825 SSU ribosomal protein S3p (S3e) Ribosome SSU bacterial gi|15607847 fig|83332.1.peg.708 CDS NC_000962 805108 805524 1 + 417 LSU ribosomal protein L16p (L10e) Ribosome LSU bacterial gi|15607848 fig|83332.1.peg.709 CDS NC_000962 805524 805757 3 + 234 LSU ribosomal protein L29p (L35e) Ribosome LSU bacterial gi|15607849 fig|83332.1.peg.710 CDS NC_000962 805754 806164 2 + 411 SSU ribosomal protein S17p (S11e) Ribosome SSU bacterial gi|15607850 fig|83332.1.peg.711 CDS NC_000962 806333 808696 2 + 2364 Arylsulfatase (EC 3.1.6.1) Sulfatases and sulfatase modifying factor 1 gi|15607851 fig|83332.1.peg.712 CDS NC_000962 808744 809643 1 + 900 Sulfatase modifying factor 1 precursor (C-alpha-formyglycine- generating enzyme 1) Sulfatases and sulfatase modifying factor 1 gi|15607852 fig|83332.1.peg.713 CDS NC_000962 809944 810885 1 + 942 Possible membrane protein - none - gi|15607853 fig|83332.1.peg.714 CDS NC_000962 811371 811739 3 + 369 LSU ribosomal protein L14p (L23e) Ribosome LSU bacterial gi|15607854 fig|83332.1.peg.715 CDS NC_000962 811740 812057 3 + 318 LSU ribosomal protein L24p (L26e) Ribosome LSU bacterial gi|15607855 fig|83332.1.peg.716 CDS NC_000962 812057 812620 2 + 564 LSU ribosomal protein L5p (L11e) Ribosome LSU bacterial gi|15607856 fig|83332.1.peg.717 CDS NC_000962 812625 812810 3 + 186 SSU ribosomal protein S14p (S29e) @ SSU ribosomal protein S14p (S29e), zinc-dependent Ribosome SSU bacterial;
Ribosome SSU bacterial gi|15607857 fig|83332.1.peg.718 CDS NC_000962 812974 813372 1 + 399 SSU ribosomal protein S8p (S15Ae) Ribosome SSU bacterial gi|15607858 fig|83332.1.peg.719 CDS NC_000962 813396 813935 3 + 540 LSU ribosomal protein L6p (L9e) Ribosome LSU bacterial gi|15607859 fig|83332.1.peg.720 CDS NC_000962 813938 814306 2 + 369 LSU ribosomal protein L18p (L5e) Ribosome LSU bacterial gi|15607860 fig|83332.1.peg.721 CDS NC_000962 814326 814988 3 + 663 SSU ribosomal protein S5p (S2e) Ribosomal protein S5p acylation;
Ribosome SSU bacterial gi|15607861 fig|83332.1.peg.722 CDS NC_000962 814991 815188 2 + 198 LSU ribosomal protein L30p (L7e) Ribosome LSU bacterial gi|15607862 fig|83332.1.peg.723 CDS NC_000962 815188 815628 1 + 441 LSU ribosomal protein L15p (L27Ae) Ribosome LSU bacterial gi|15607863 fig|83332.1.peg.724 CDS NC_000962 815661 817532 3 + 1872 Possible protease IV SppA (endopeptidase IV) (signal peptide peptidase) - none - gi|15607864 fig|83332.1.peg.725 CDS NC_000962 818442 817537 -3 - 906 Putative S-adenosyl-L-methionine-dependent methyltransferase - none - gi|15607865 fig|83332.1.peg.726 CDS NC_000962 819638 818535 -2 - 1104 hypothetical protein - none - gi|15607866 fig|83332.1.peg.727 CDS NC_000962 820497 819841 -3 - 657 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - none - gi|15607867 fig|83332.1.peg.728 CDS NC_000962 821474 820494 -2 - 981 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) Glycine and Serine Utilization;
Pyridoxin (Vitamin B6) Biosynthesis;
Serine Biosynthesis gi|15607868 fig|83332.1.peg.729 CDS NC_000962 821505 822851 3 + 1347 Putative xylulose kinase (EC 2.7.1.17) - none - gi|15607869 fig|83332.1.peg.730 CDS NC_000962 822864 823592 3 + 729 hypothetical protein Rv0730 - none - gi|15607870 fig|83332.1.peg.731 CDS NC_000962 824637 823681 -3 - 957 FIG00819993: hypothetical protein - none - gi|15607871 fig|83332.1.peg.732 CDS NC_000962 824798 826123 2 + 1326 Preprotein translocase secY subunit (TC 3.A.5.1.1) - none - gi|15607872 fig|83332.1.peg.733 CDS NC_000962 826120 826665 1 + 546 Adenylate kinase (EC 2.7.4.3) Purine conversions gi|15607873 fig|83332.1.peg.734 CDS NC_000962 826668 827468 3 + 801 Methionine aminopeptidase (EC 3.4.11.18) CBSS-312309.3.peg.1965;
Translation termination factors bacterial gi|15607874 fig|83332.1.peg.735 CDS NC_000962 827541 828074 3 + 534 (MTV041.09, sigL), len: 177. Probable RNA polymerase sigma factor, similar to many proteins of the extracytoplasmatic function (ECF) subfamily e.g. Myxococcus xanthus, FASTA scores: sp|Q06909|CARQ_MYXXA RNA POLYMERASE SIGMA FACTOR CARQ. (174 aa).opt: 251 z-score: 327.6 E(): 9.6e-11. 32.9% identity in 161 aa overlap; Also similar to MTCI61_4, MTU87242_1 ,and MLU15180_30. TBparse score is 0.902. Contains PS01063 Sigma-70 factors ECF subfamily signature and probable helix-turn helix motif from aa 140-161 - none - gi|15607875 fig|83332.1.peg.736 CDS NC_000962 828138 828890 3 + 753 Possible membrane protein - none - gi|15607876 fig|83332.1.peg.737 CDS NC_000962 829205 829702 2 + 498 Transcriptional regulator, MarR family - none - gi|15607877 fig|83332.1.peg.738 CDS NC_000962 830060 830608 2 + 549 FIG00822571: hypothetical protein - none - gi|15607878 fig|83332.1.peg.739 CDS NC_000962 830853 831659 3 + 807 hypothetical protein Rv0739 - none - gi|15607879 fig|83332.1.peg.740 CDS NC_000962 831774 832301 3 + 528 hypothetical protein Rv0740 - none - gi|15607880 fig|83332.1.peg.741 CDS NC_000962 832532 832846 2 + 315 Mobile element protein - none - gi|15607881 fig|83332.1.peg.742 CDS NC_000962 832979 833506 2 + 528 (MTV041.16), len: 175. Unknown, member of PE-family, PGRS subfamily of glycine-rich protein, similar to many M. tuberculosis PGRS-type proteins. e.g. gp|Z78020|MTCY1A11_25 M. tuberculosis cosmi (498 aa). Similarity suggests ORF starts with ATA start codon. FASTA scores:opt: 766 z-score: 582.4 E(): 6.1e-25. 73.6% identity in 178 aa overlap. TBparse score is 0.846 - none - gi|15607882 fig|83332.1.peg.743 CDS NC_000962 834441 833884 -3 - 558 hypothetical protein Rv0743c - none - gi|15607883 fig|83332.1.peg.744 CDS NC_000962 834944 834438 -2 - 507 hypothetical protein Rv0744c - none - gi|15607884 fig|83332.1.peg.745 CDS NC_000962 835152 835679 3 + 528 hypothetical protein Rv0745 - none - gi|15607885 fig|83332.1.peg.746 CDS NC_000962 835699 838050 1 + 2352 PE-PGRS virulence associated protein - none - gi|15607886 fig|83332.1.peg.747 CDS NC_000962 838449 840854 3 + 2406 PE-PGRS virulence associated protein - none - gi|15607887 fig|83332.1.peg.748 CDS NC_000962 840945 841202 3 + 258 hypothetical protein Rv0748 - none - gi|15607888 fig|83332.1.peg.749 CDS NC_000962 841226 841654 2 + 429 Toxin 1, PIN domain Toxin-Antitoxin MT1 gi|15607889 fig|83332.1.peg.750 CDS NC_000962 842031 842276 3 + 246 hypothetical protein Rv0750 - none - gi|15607890 fig|83332.1.peg.751 CDS NC_000962 843229 842345 -1 - 885 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) Valine degradation gi|15607891 fig|83332.1.peg.752 CDS NC_000962 844412 843240 -2 - 1173 Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.8.1) Isoleucine degradation gi|15607892 fig|83332.1.peg.753 CDS NC_000962 845951 844419 -2 - 1533 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) Valine degradation gi|15607893 fig|83332.1.peg.754 CDS NC_000962 846157 847911 1 + 1755 (MTV041.28), len: 584. Unknown glycine richprotein, similar to other PE_PGRS type hypothetical proteins e.g. gp|AL0212|MTV008_46 M. tuberculosis sequenc (1660 aa); 48.7% identity in 345 aa overlap or gp|Z80225|MTCY441_4M. tuberculosis cosmid (778 aa); 41.6% identity in 442 aaoverlap - none - gi|15607894 fig|83332.1.peg.755 CDS NC_000962 850038 848101 -3 - 1938 (MTV041.29), len: 645. Member of PPE family, (Gly-, Ala-, Asn-rich PPE family). Similar to gp|Z82098|MTCY3C7_23 M. tuberculosis cosmid (582 aa), 56.1% identityin 636 aa overlap; or gp|Z92774|MTCY6G11_5 M. tuberculosiscosmid (552 aa), 55.8% identity in 590 aa overlap. - none - gi|15607895 fig|83332.1.peg.756 CDS NC_000962 851464 850739 -1 - 726 hypothetical protein Rv0756c - none - gi|15607896 fig|83332.1.peg.757 CDS NC_000962 851606 852349 2 + 744 (MTCY369.02), len: 247, phoP-like, similar to PHOP_BACSU P13792 alkaline phosphatase synthesis transcription regulatory protein (240 aa), fasta scores, opt: 594, E(): 2.3e-33, (41.0% identity in 234 aa overlap), also similar to MTCY31.31c (45.4% identity in 229 aa overlap), MTCY10G2_16, MTU88959_1 Mycobacterium tuberculosis response regulator (257 aa, 46.7% identity in 225 aa overlap) etc. - none - gi|15607897 fig|83332.1.peg.758 CDS NC_000962 852394 853851 1 + 1458 (MTCY369.03), len: 485, phoR-like similar to PHOR_BACSU P23545 alkaline phosphatase synthesis sensor (579 aa), fasta scores, opt: 515, E(): 1.9e-25, (40.0% identity in 230 aa overlap), also similar to MTCY20G9.16, 34.5% identity in 264 aa overlap), MTU88959_2 Mycobacterium tuberculosis sensor (509 aa), MTCY10G2_17, etc. - none - gi|15607898 fig|83332.1.peg.759 CDS NC_000962 854155 853823 -1 - 333 hypothetical protein Rv0759c - none - gi|15607899 fig|83332.1.peg.760 CDS NC_000962 854684 854265 -2 - 420 hypothetical protein Rv0760c - none - gi|15607900 fig|83332.1.peg.761 CDS NC_000962 855824 854697 -2 - 1128 Alcohol dehydrogenase B (EC 1.1.1.1) - none - gi|15607901 fig|83332.1.peg.762 CDS NC_000962 856468 855923 -1 - 546 hypothetical protein Rv0762c - none - gi|15607902 fig|83332.1.peg.763 CDS NC_000962 856677 856471 -3 - 207 Ferredoxin Inorganic Sulfur Assimilation;
Soluble cytochromes and functionally related electron carriers gi|15607903 fig|83332.1.peg.764 CDS NC_000962 858035 856680 -2 - 1356 Cytochrome P450 51 - none - gi|15607904 fig|83332.1.peg.765 CDS NC_000962 858862 858035 -1 - 828 oxidoreductase, short-chain dehydrogenase/reductase family - none - gi|15607905 fig|83332.1.peg.766 CDS NC_000962 860070 858862 -3 - 1209 Cytochrome P450 123 - none - gi|15607906 fig|83332.1.peg.767 CDS NC_000962 860708 860067 -2 - 642 Transcriptional regulator, TetR family - none - gi|15607907 fig|83332.1.peg.768 CDS NC_000962 860910 862379 3 + 1470 Aldehyde dehydrogenase (EC 1.2.1.3) Glycerolipid and Glycerophospholipid Metabolism in Bacteria;
Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate gi|15607908 fig|83332.1.peg.769 CDS NC_000962 862410 863156 3 + 747 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) - none - gi|15607909 fig|83332.1.peg.770 CDS NC_000962 863254 864141 1 + 888 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) Valine degradation gi|15607910 fig|83332.1.peg.771 CDS NC_000962 864138 864572 3 + 435 4-carboxymuconolactone decarboxylase (EC 4.1.1.44) - none - gi|15607911 fig|83332.1.peg.772 CDS NC_000962 864584 865852 2 + 1269 Phosphoribosylamine--glycine ligase (EC 6.3.4.13) De Novo Purine Biosynthesis gi|15607912 fig|83332.1.peg.773 CDS NC_000962 867387 865849 -3 - 1539 Gamma-glutamyltranspeptidase (EC 2.3.2.2) - none - gi|15607913 fig|83332.1.peg.774 CDS NC_000962 868376 867438 -2 - 939 hypothetical protein Rv0774c - none - gi|15607914 fig|83332.1.peg.775 CDS NC_000962 868405 869028 1 + 624 Transcriptional regulator, TetR family - none - gi|15607915 fig|83332.1.peg.776 CDS NC_000962 869761 868982 -1 - 780 hypothetical protein Rv0776c - none - gi|15607916 fig|83332.1.peg.777 CDS NC_000962 870006 871424 3 + 1419 Adenylosuccinate lyase (EC 4.3.2.2) De Novo Purine Biosynthesis;
Purine conversions gi|15607917 fig|83332.1.peg.778 CDS NC_000962 871429 872673 1 + 1245 Cytochrome P450 126A3 - none - gi|15607918 fig|83332.1.peg.779 CDS NC_000962 873290 872670 -2 - 621 hypothetical protein Rv0779c - none - gi|15607919 fig|83332.1.peg.780 CDS NC_000962 873341 874234 2 + 894 Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) De Novo Purine Biosynthesis gi|15607920 fig|83332.1.peg.781 CDS NC_000962 874231 874941 1 + 711 Protease II (EC 3.4.21.83) - none - gi|15607921 fig|83332.1.peg.782 CDS NC_000962 874730 876388 2 + 1659 (MTCY369.26), len: 552, ptrBa, similar to the C-terminal region of PTRB_ECOLI P24555 protease ii (707aa), fasta scores, opt: 1251, E(): 0, (42.7% identity in 489 aa overlap), MTCY369.25 and 26 appear to be a frameshifted homologue of protease II, we can find no error in the cosmid sequence to account for this. - none - gi|15607922 fig|83332.1.peg.783 CDS NC_000962 878438 876816 -2 - 1623 hypothetical protein Rv0783c - none - gi|15607923 fig|83332.1.peg.784 CDS NC_000962 878636 879322 2 + 687 hypothetical protein Rv0784 - none - gi|15607924 fig|83332.1.peg.785 CDS NC_000962 879338 881038 2 + 1701 hypothetical protein Rv0785 - none - gi|15607925 fig|83332.1.peg.786 CDS NC_000962 881462 881073 -2 - 390 hypothetical protein Rv0786c - none - gi|15607926 fig|83332.1.peg.787 CDS NC_000962 881457 882416 3 + 960 hypothetical protein Rv0787 - none - gi|15607927 fig|83332.1.peg.788 CDS NC_000962 882522 882761 3 + 240 Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3) De Novo Purine Biosynthesis gi|15611068 fig|83332.1.peg.789 CDS NC_000962 882758 883432 2 + 675 Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3) De Novo Purine Biosynthesis gi|15607928 fig|83332.1.peg.790 CDS NC_000962 884048 883449 -2 - 600 hypothetical protein Rv0789c - none - gi|15607929 fig|83332.1.peg.791 CDS NC_000962 884798 884070 -2 - 729 hypothetical protein Rv0790c - none - gi|15607930 fig|83332.1.peg.792 CDS NC_000962 885838 884795 -1 - 1044 N5,N10-methylenetetrahydromethanopterin reductase-related protein, BCG_0844c family - none - gi|15607931 fig|83332.1.peg.793 CDS NC_000962 886644 885835 -3 - 810 Transcriptional regulator, GntR family - none - gi|15607932 fig|83332.1.peg.794 CDS NC_000962 886717 887022 1 + 306 Putative antibiotic biosynthesis monooxygenase - none - gi|15607933 fig|83332.1.peg.795 CDS NC_000962 888634 887135 -1 - 1500 PF00070 family, FAD-dependent NAD(P)-disulphide oxidoreductase Mercuric reductase gi|15607934 fig|83332.1.peg.796 CDS NC_000962 889070 889396 2 + 327 Mobile element protein - none - gi|15607935 fig|83332.1.peg.797 CDS NC_000962 889393 890331 1 + 939 Mobile element protein - none - gi|15607936 fig|83332.1.peg.798 CDS NC_000962 890386 891480 1 + 1095 hypothetical protein Rv0797 - none - gi|15607937 fig|83332.1.peg.799 CDS NC_000962 892267 891470 -1 - 798 Encapsulating protein for a DyP-type peroxidase or ferritin-like protein oligomers Biogenesis of c-type cytochromes;
Encapsulating protein for DyP-type peroxidase and ferritin-like protein oligomers gi|15607938 fig|83332.1.peg.800 CDS NC_000962 893271 892264 -3 - 1008 Predicted dye-decolorizing peroxidase (DyP), encapsulated subgroup Biogenesis of c-type cytochromes;
Encapsulating protein for DyP-type peroxidase and ferritin-like protein oligomers gi|15607939 fig|83332.1.peg.801 CDS NC_000962 893316 894617 3 + 1302 Putative aminopeptidase ( EC:3.4.11.- ) Encapsulating protein for DyP-type peroxidase and ferritin-like protein oligomers gi|15607940 fig|83332.1.peg.802 CDS NC_000962 894629 894976 2 + 348 Glyoxalase family protein - none - gi|15607941 fig|83332.1.peg.803 CDS NC_000962 895626 894970 -3 - 657 hypothetical protein Rv0802c - none - gi|15607942 fig|83332.1.peg.804 CDS NC_000962 895818 898082 3 + 2265 Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) De Novo Purine Biosynthesis gi|15607943 fig|83332.1.peg.805 CDS NC_000962 898079 898708 2 + 630 hypothetical protein Rv0804 - none - gi|15607944 fig|83332.1.peg.806 CDS NC_000962 898829 899785 2 + 957 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17) cAMP signaling in bacteria gi|15607945 fig|83332.1.peg.807 CDS NC_000962 901328 899730 -2 - 1599 (MTCY07H7A.03), len: 532 aa, cpsY, highly similar to M. leprae Q50025 CPSY (542 aa), fasta scores, opt: 2964, E(): 0, (82.3% identity in 530 aa overlap), some similarity to NEISSERIA MENINGITIDIS Q51151 capsule gene complex UPD-glucose-4-epimerase (373 aa), fasta scores, opt: 496, E(): 9.5e-27, (29.3% identity in 358 aa overlap) - none - gi|15607946 fig|83332.1.peg.808 CDS NC_000962 901633 902022 1 + 390 hypothetical protein - none - gi|15607947 fig|83332.1.peg.809 CDS NC_000962 902109 903692 3 + 1584 Amidophosphoribosyltransferase (EC 2.4.2.14) De Novo Purine Biosynthesis gi|15607948 fig|83332.1.peg.810 CDS NC_000962 903723 904817 3 + 1095 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) De Novo Purine Biosynthesis gi|15607949 fig|83332.1.peg.811 CDS NC_000962 905085 904903 -3 - 183 hypothetical protein Rv0810c - none - gi|15607950 fig|83332.1.peg.812 CDS NC_000962 906338 905232 -2 - 1107 Folate-dependent protein for Fe/S cluster synthesis/repair in oxidative stress - none - gi|15607951 fig|83332.1.peg.813 CDS NC_000962 906421 907290 1 + 870 Aminodeoxychorismate lyase (EC 4.1.3.38) # PabAc Chorismate: Intermediate for synthesis of Tryptophan, PAPA antibiotics, PABA, 3-hydroxyanthranilate and more.;
Folate Biosynthesis;
Tryptophan synthesis gi|15607952 fig|83332.1.peg.814 CDS NC_000962 908016 907336 -3 - 681 DUF1794 - none - gi|15607953 fig|83332.1.peg.815 CDS NC_000962 908481 908179 -3 - 303 probable sseC protein - none - gi|15607954 fig|83332.1.peg.816 CDS NC_000962 909316 908483 -1 - 834 Thiosulfate sulfurtransferase, rhodanese (EC 2.8.1.1) Single-Rhodanese-domain proteins gi|15607955 fig|83332.1.peg.817 CDS NC_000962 910031 909609 -2 - 423 Thioredoxin - none - gi|15607956 fig|83332.1.peg.818 CDS NC_000962 910840 910028 -1 - 813 hypothetical protein - none - gi|15607957 fig|83332.1.peg.819 CDS NC_000962 910970 911737 2 + 768 GlnR-family transcriptional regulator - none - gi|15607958 fig|83332.1.peg.820 CDS NC_000962 911734 912681 1 + 948 Acetyl-CoA:Cys-GlcN-Ins acetyltransferase, mycothiol synthase MshD Glutathione analogs: mycothiol;
tRNA aminoacylation, Cys gi|15607959 fig|83332.1.peg.821 CDS NC_000962 912724 913500 1 + 777 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) High affinity phosphate transporter and control of PHO regulon;
Phosphate metabolism gi|15607960 fig|83332.1.peg.822 CDS NC_000962 914197 913556 -1 - 642 Phosphate transport system regulatory protein PhoU Glutathione analogs: mycothiol;
High affinity phosphate transporter and control of PHO regulon;
Phosphate metabolism gi|15607961 fig|83332.1.peg.823 CDS NC_000962 916309 914255 -1 - 2055 Cell envelope-associated transcriptional attenuator LytR-CpsA-Psr, subfamily A1 (as in PMID19099556) Cell envelope-associated LytR-CpsA-Psr transcriptional attenuators gi|15607962 fig|83332.1.peg.824 CDS NC_000962 917644 916475 -1 - 1170 tRNA dihydrouridine synthase B (EC 1.-.-.-) Mycobacterium virulence operon involved in lipid metabolism;
tRNA modification Bacteria gi|15607963 fig|83332.1.peg.825 CDS NC_000962 918748 917732 -1 - 1017 Fatty acid desaturase occurring in virulence cluster Mycobacterium virulence operon involved in lipid metabolism gi|15607964 fig|83332.1.peg.826 CDS NC_000962 919551 918910 -3 - 642 Transcriptional regulator, TetR family - none - gi|15607965 fig|83332.1.peg.827 CDS NC_000962 919632 920687 3 + 1056 hypothetical protein Rv0826 - none - gi|15607966 fig|83332.1.peg.828 CDS NC_000962 921131 920739 -2 - 393 transcriptional regulator, ArsR family - none - gi|15607967 fig|83332.1.peg.829 CDS NC_000962 921611 921189 -2 - 423 Deaminase - none - gi|15607968 fig|83332.1.peg.830 CDS NC_000962 921573 921863 3 + 291 Mobile element protein - none - gi|15607969 fig|83332.1.peg.831 CDS NC_000962 921968 922873 2 + 906 O-Methyltransferase involved in polyketide biosynthesis - none - gi|15607970 fig|83332.1.peg.832 CDS NC_000962 923707 922892 -1 - 816 hypothetical protein Rv0831c - none - gi|15607971 fig|83332.1.peg.833 CDS NC_000962 924949 925362 1 + 414 (MTV043.24), len: 137. Member of Mycobacterium tuberculosis PE family, possibly PGRS subfamily, similar to many others e.g. MTCY1A11.25c (498 aa). Appears to have incurred frameshift as next orf should be continuation, sequence has been checked but no error found. FASTA scores: gp|Z78020|MTCY1A11_25 (498 aa) opt: 529 z-score: 529.9 E(): 5.2e-22; 61.8% identity in 136 aa overlap. TBparse score is 0.875 - none - gi|15607972 fig|83332.1.peg.834 CDS NC_000962 925359 927608 3 + 2250 (MTV043.25), len: 749. Mycobacterium tuberculosis PE_PGRS family member but lacking N-terminal domain (present in preceding orf) , possibly due to frameshift. Very similar to MTCY28_25 (914 aa) . FASTA scores: Z95890|MTCY28_25 (914 aa) opt: 2726 z-score: 1609.4 E(): 0; 60.1% identity in 776 aa overlap. TBparse score is 0.859 - none - gi|15607973 fig|83332.1.peg.835 CDS NC_000962 930483 927835 -3 - 2649 (MTV043.26c), len: 882. Member of PE_PGRS subfamily of Mycobacterium tuberculosis Gly-, Ala-rich PE family. similar to MTCY493_4. FASTA scores: Z95844|MTCY493_4(1329 aa) opt: 2577 z-score: 1546.5 E(): 0; 52.0% identity in 950 aa overlap. TBparse score is 0.860 - none - gi|15607974 fig|83332.1.peg.836 CDS NC_000962 930951 931595 3 + 645 (MTV043.27), len: 214. Unknown, possibly lipoprotein. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site. FASTA scores: . TBparse score is 0.944 - none - gi|15607975 fig|83332.1.peg.837 CDS NC_000962 932930 932277 -2 - 654 hypothetical protein Rv0836c - none - gi|15607976 fig|83332.1.peg.838 CDS NC_000962 934029 933001 -3 - 1029 hypothetical protein Rv0837c - none - gi|15607977 fig|83332.1.peg.839 CDS NC_000962 934718 935488 2 + 771 (MTV043.31), len: 256. Unknown, probably lipoprotein, contains signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Some similarity to D-ALANYL-D-ALANINE DIPEPTIDASE (202 aa). FASTA scores: Transposon Tn1546 Q06241|VANX_ENTFC D-ALANYL-D-ALANINE DIPEPTIDASE (E (202 aa) opt: 198 z-score: 232.5 E(): 1.9e-05; 28.1% identity in 199 aa overlap. TBparse score is 0.931 - none - gi|15607978 fig|83332.1.peg.840 CDS NC_000962 935575 936387 1 + 813 hypothetical protein Rv0839 - none - gi|15607979 fig|83332.1.peg.841 CDS NC_000962 937315 936455 -1 - 861 hypothetical protein Rv0840c - none - gi|15607980 fig|83332.1.peg.842 CDS NC_000962 937896 937480 -3 - 417 hypothetical protein Rv0841c - none - gi|15607981 fig|83332.1.peg.843 CDS NC_000962 938110 939402 1 + 1293 hypothetical protein Rv0842 - none - gi|15607982 fig|83332.1.peg.844 CDS NC_000962 939386 940390 2 + 1005 PROBABLE DEHYDROGENASE - none - gi|15607983 fig|83332.1.peg.845 CDS NC_000962 941104 940454 -1 - 651 (MTV043.37c, narL), len: 216. Probable NarL, Nitrate/nitrite response regulator protein similar to many e.g. Synechocystis sp. PCC6803 D64005|SYCSLRG_24 (209 aa). FASTA scores: D64005|SYCSLRG_24 (209 aa) opt: 438 z-score: 557.5 E(): 1.5e-23; 34.6% identity in 208 aa overlap. TBparse score is 0.890. Contains probable helix-turn helix motif from aa 171-192 - none - gi|15607984 fig|83332.1.peg.846 CDS NC_000962 941188 942465 1 + 1278 hypothetical protein Rv0845 - none - gi|15607985 fig|83332.1.peg.847 CDS NC_000962 944192 942678 -2 - 1515 Multicopper oxidase Copper homeostasis gi|15607986 fig|83332.1.peg.848 CDS NC_000962 944341 944733 1 + 393 (MTV043.40), len: 130. Unknown, possibly lipoprotein contains possible signal sequence and PS00013 Prokaryotic membrane lipoprotein lipid attachment site. TBparse score is 0.920 - none - gi|15607987 fig|83332.1.peg.849 CDS NC_000962 944936 946054 2 + 1119 Cysteine synthase (EC 2.5.1.47) Cysteine Biosynthesis;
Methionine Biosynthesis gi|15607988 fig|83332.1.peg.850 CDS NC_000962 946054 947313 1 + 1260 Probable conserved integral membrane transport protein - none - gi|15607989 fig|83332.1.peg.851 CDS NC_000962 947310 947642 3 + 333 hypothetical protein Rv0850 - none - gi|15607990 fig|83332.1.peg.852 CDS NC_000962 948466 947639 -1 - 828 hypothetical protein Rv0851c - none - gi|15607991 fig|83332.1.peg.853 CDS NC_000962 948557 949393 2 + 837 (MTV043.45), len: 278. fadD16 similar in part to various CoA ligases. eg. gp|D49366|LEP4CCOALA_1Lithospermum erythrorhizon mRNA (636 aa), opt: 134 z-score: 162.8 E(): 0.15; 26.8% identity in 213 aa overlap, orgp|L09229|HUMFACAL_1 Human long-chain acyl-coenzyme A (699aa),50.0% identity in 40 aa overlap. Contains PS00626 Regulator of chromosome condensation (RCC1) signature 2 - none - gi|15607992 fig|83332.1.peg.854 CDS NC_000962 951116 949434 -2 - 1683 Pyruvate decarboxylase (EC 4.1.1.1); Alpha-keto-acid decarboxylase (EC 4.1.1.-) Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate gi|15607993 fig|83332.1.peg.855 CDS NC_000962 951181 951624 1 + 444 hypothetical protein Rv0854 - none - gi|15607994 fig|83332.1.peg.856 CDS NC_000962 951630 952709 3 + 1080 Alpha-methylacyl-CoA racemase (EC 5.1.99.4) - none - gi|15607995 fig|83332.1.peg.857 CDS NC_000962 952823 953227 2 + 405 hypothetical protein Rv0856 - none - gi|15607996 fig|83332.1.peg.858 CDS NC_000962 953255 953628 2 + 374 hypothetical protein Rv0857 - none - gi|15607997 fig|83332.1.peg.859 CDS NC_000962 954918 953725 -3 - 1194 Glutamine-dependent 2-keto-4-methylthiobutyrate transaminase - none - gi|15607998 fig|83332.1.peg.860 CDS NC_000962 955075 956286 1 + 1212 3-ketoacyl-CoA thiolase [isoleucine degradation] (EC 2.3.1.16) Isoleucine degradation gi|15607999 fig|83332.1.peg.861 CDS NC_000962 956291 958453 2 + 2163 Enoyl-CoA hydratase [isoleucine degradation] (EC 4.2.1.17) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) Acetyl-CoA fermentation to Butyrate;
Acetyl-CoA fermentation to Butyrate;
Fatty acid metabolism cluster;
Fatty acid metabolism cluster;
Isoleucine degradation;
Isoleucine degradation;
Polyhydroxybutyrate metabolism;
Polyhydroxybutyrate metabolism;
Valine degradation gi|15608000 fig|83332.1.peg.862 CDS NC_000962 960149 958521 -2 - 1629 DNA repair helicase - none - gi|15608001 fig|83332.1.peg.863 CDS NC_000962 962610 960340 -3 - 2271 probable DNA-binding protein - none - gi|15608002 fig|83332.1.peg.864 CDS NC_000962 962597 962878 2 + 282 FIG057355: hypothetical protein - none - gi|15608003 fig|83332.1.peg.865 CDS NC_000962 962888 963391 2 + 504 Molybdenum cofactor biosynthesis protein MoaC Molybdenum cofactor biosynthesis;
ar-104-EC Molybdenum cofactor biosynthesis moaABCDE gi|15608004 fig|83332.1.peg.866 CDS NC_000962 963388 963870 1 + 483 Molybdenum cofactor biosynthesis protein MoaB Involvement of a novel heat shock protein (Hsp22.5) in mycobacterial persistence;
Molybdenum cofactor biosynthesis;
ar-104-EC Molybdenum cofactor biosynthesis moaABCDE gi|15608005 fig|83332.1.peg.867 CDS NC_000962 963867 964292 3 + 426 Molybdenum cofactor biosynthesis protein MoaE Molybdenum cofactor biosynthesis;
ar-104-EC Molybdenum cofactor biosynthesis moaABCDE gi|15608006 fig|83332.1.peg.868 CDS NC_000962 965533 964310 -1 - 1224 hypothetical protein Rv0867c - none - gi|15608007 fig|83332.1.peg.869 CDS NC_000962 966259 965981 -1 - 279 Molybdenum cofactor biosynthesis protein MoaD Molybdenum cofactor biosynthesis;
ar-104-EC Molybdenum cofactor biosynthesis moaABCDE gi|15608008 fig|83332.1.peg.870 CDS NC_000962 967345 966263 -1 - 1083 Molybdenum cofactor biosynthesis protein MoaA Molybdenum cofactor biosynthesis;
ar-104-EC Molybdenum cofactor biosynthesis moaABCDE gi|15608009 fig|83332.1.peg.871 CDS NC_000962 967731 967342 -3 - 390 FIG020413: transmembrane protein - none - gi|15608010 fig|83332.1.peg.872 CDS NC_000962 967896 968303 3 + 408 Cold shock protein CspC Cold shock, CspA family of proteins gi|15608011 fig|83332.1.peg.873 CDS NC_000962 970242 968422 -3 - 1821 PE-PGRS virulence associated protein - none - gi|15608012 fig|83332.1.peg.874 CDS NC_000962 970503 972455 3 + 1953 Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.8.1) Isoleucine degradation gi|15608013 fig|83332.1.peg.875 CDS NC_000962 973704 972544 -3 - 1161 hypothetical protein Rv0874c - none - gi|15608014 fig|83332.1.peg.876 CDS NC_000962 974292 973804 -3 - 489 hypothetical protein Rv0875c - none - gi|15608015 fig|83332.1.peg.877 CDS NC_000962 975935 974289 -2 - 1647 hypothetical protein Rv0876c - none - gi|15608016 fig|83332.1.peg.878 CDS NC_000962 976073 976861 2 + 789 hypothetical protein Rv0877 - none - gi|15608017 fig|83332.1.peg.879 CDS NC_000962 978201 976870 -3 - 1332 (MTCY31.06c), len: 443, unknown; similar to YHS6_MYCTU P42611 hypothetical 50.6 kd protein in hsp65 3' region, (517 aa), FASTA scores: opt: 1044, z-score: 954.9, E(): 0, (47.4% identity in 397 aa overlap). Similar also to MTV014_3; MTCI65_2, MTCY98_24, MTCY3C7_23, MTCY48_17, MTV004_5,MTV004_3 etc. - none - gi|15608018 fig|83332.1.peg.880 CDS NC_000962 978754 978479 -1 - 276 hypothetical protein Rv0879c - none - gi|15608019 fig|83332.1.peg.881 CDS NC_000962 978932 979363 2 + 432 Transcriptional regulator, MarR family - none - gi|15608020 fig|83332.1.peg.882 CDS NC_000962 979360 980226 1 + 867 hypothetical protein Rv0881 - none - gi|15608021 fig|83332.1.peg.883 CDS NC_000962 980223 980507 3 + 285 hypothetical protein Rv0882 - none - gi|15608022 fig|83332.1.peg.884 CDS NC_000962 981265 980504 -1 - 762 hypothetical protein Rv0883c - none - gi|15608023 fig|83332.1.peg.885 CDS NC_000962 982552 981422 -1 - 1131 Phosphoserine aminotransferase (EC 2.6.1.52) Glycine and Serine Utilization;
Pyridoxin (Vitamin B6) Biosynthesis;
Serine Biosynthesis gi|15608024 fig|83332.1.peg.886 CDS NC_000962 982760 983782 2 + 1023 hypothetical protein Rv0885 - none - gi|15608025 fig|83332.1.peg.887 CDS NC_000962 983801 985528 2 + 1728 Ferredoxin / Ferredoxin--NADP(+) reductase, actinobacterial (eukaryote-like) type (EC 1.18.1.2) Inorganic Sulfur Assimilation;
Inorganic Sulfur Assimilation;
Soluble cytochromes and functionally related electron carriers gi|15608026 fig|83332.1.peg.888 CDS NC_000962 985969 985511 -1 - 459 hypothetical protein Rv0887c - none - gi|15608027 fig|83332.1.peg.889 CDS NC_000962 987231 988703 3 + 1473 hypothetical protein Rv0888 - none - gi|15608028 fig|83332.1.peg.890 CDS NC_000962 989859 988738 -3 - 1122 Citrate synthase (si) (EC 2.3.3.1) Biogenesis of c-type cytochromes;
Glyoxylate bypass;
Serine-glyoxylate cycle;
TCA Cycle gi|15608029 fig|83332.1.peg.891 CDS NC_000962 992594 989946 -2 - 2649 Disease resistance domain-containing protein / Transcriptional regulator, LuxR family - none - gi|15608030 fig|83332.1.peg.892 CDS NC_000962 993453 992596 -3 - 858 Adenylyl cyclase class-3/4/guanylyl cyclase - none - gi|15608031 fig|83332.1.peg.893 CDS NC_000962 993851 995338 2 + 1488 hypothetical protein Rv0892 - none - gi|15608032 fig|83332.1.peg.894 CDS NC_000962 996293 995316 -2 - 978 hypothetical protein Rv0893c - none - gi|15608033 fig|83332.1.peg.895 CDS NC_000962 996522 997703 3 + 1182 Disease resistance domain-containing protein - none - gi|15608034 fig|83332.1.peg.896 CDS NC_000962 997780 999297 1 + 1518 Diacyglycerol O-acyltransferase (EC 2.3.1.20) - none - gi|15608035 fig|83332.1.peg.897 CDS NC_000962 999470 1000765 2 + 1296 Citrate synthase (si) (EC 2.3.3.1) Biogenesis of c-type cytochromes;
Glyoxylate bypass;
Serine-glyoxylate cycle;
TCA Cycle gi|15608036 fig|83332.1.peg.898 CDS NC_000962 1002413 1000806 -2 - 1608 Beta-carotene ketolase (EC 1.14.-.-) Carotenoids gi|15608037 fig|83332.1.peg.899 CDS NC_000962 1002702 1002439 -3 - 264 hypothetical protein Rv0898c - none - gi|15608038 fig|83332.1.peg.900 CDS NC_000962 1002810 1003790 3 + 981 Outer membrane protein - none - gi|15608039 fig|83332.1.peg.901 CDS NC_000962 1003803 1003955 3 + 153 hypothetical protein Rv0900 - none - gi|15608040 fig|83332.1.peg.902 CDS NC_000962 1003955 1004482 2 + 528 hypothetical protein Rv0901 - none - gi|15608041 fig|83332.1.peg.903 CDS NC_000962 1005839 1004499 -2 - 1341 hypothetical protein Rv0902c - none - gi|15608042 fig|83332.1.peg.904 CDS NC_000962 1006560 1005850 -3 - 711 hypothetical protein Rv0903c - none - gi|15608043 fig|83332.1.peg.905 CDS NC_000962 1008178 1006691 -1 - 1488 Acetyl-coenzyme A carboxyl transferase alpha chain (EC 6.4.1.2) / Acetyl-coenzyme A carboxyl transferase beta chain (EC 6.4.1.2) Fatty Acid Biosynthesis FASII;
Fatty Acid Biosynthesis FASII gi|15608044 fig|83332.1.peg.906 CDS NC_000962 1008205 1008936 1 + 732 Enoyl-CoA hydratase (EC 4.2.1.17) Acetyl-CoA fermentation to Butyrate;
Fatty acid metabolism cluster gi|15608045 fig|83332.1.peg.907 CDS NC_000962 1008942 1010060 3 + 1119 hypothetical protein Rv0906 - none - gi|15608046 fig|83332.1.peg.908 CDS NC_000962 1010134 1011732 1 + 1599 Beta-lactamase (EC 3.5.2.6) Beta-lactamase gi|15608047 fig|83332.1.peg.909 CDS NC_000962 1011729 1014122 3 + 2394 Cation-transporting ATPase, E1-E2 family Magnesium transport gi|15608048 fig|83332.1.peg.910 CDS NC_000962 1014679 1014858 1 + 180 hypothetical protein Rv0909 - none - gi|15608049 fig|83332.1.peg.911 CDS NC_000962 1014864 1015298 3 + 435 hypothetical protein - none - gi|15608050 fig|83332.1.peg.912 CDS NC_000962 1015396 1016169 1 + 774 Putative hydroxylase - none - gi|15608051 fig|83332.1.peg.913 CDS NC_000962 1016234 1016683 2 + 450 Possible membrane protein - none - gi|15608052 fig|83332.1.peg.914 CDS NC_000962 1018723 1017215 -1 - 1509 hypothetical protein Rv0913c - none - gi|15608053 fig|83332.1.peg.915 CDS NC_000962 1019963 1018725 -2 - 1239 3-ketoacyl-CoA thiolase (EC 2.3.1.16) Biotin synthesis cluster;
Fatty acid metabolism cluster gi|15608054 fig|83332.1.peg.916 CDS NC_000962 1021327 1020056 -1 - 1272 (MTCY21C12.09c), len: 423; PPE-family protein, similar to many such as MTCY03A2.22c, 4e-27; MTCY03C7.24c, 5.5e-27; MTCY274.23c, 7.3e-27; MTCY98.0029c, 6.6e-23;MTCY02B10.25c, 5.2e-21; MTCY13E10.17c, 6.2e-21; MTCY31.06c,3.2e-20; MTCY03C7.23, 5.4e-20; MTCY98.0034c, 1.3e-19; MTCY03A2.14, 1.8e-19; MTCY48.17, 4.9e-19; MTCY03C7.17c, 2.9e-16.FASTA best: YX23_MYCTU Q10813 hypothetical 41.1 kd proteincy274.23c (404 aa)opt: 795 z-score: 734.5 E(): 6.4e-34;(40.9% identity in 401 aa overlap); contains PS00626 Regulator of chromosome condensation(RCC1) signature 2 - none - gi|15608055 fig|83332.1.peg.917 CDS NC_000962 1021641 1021342 -3 - 300 (MTCY21C12.10c), len: 99. PE-family protein, similar to many e.g. MTC1A11.04, 8.7e-10; MTCY359.33, 8.7e-10; MTCY98.0011c, 9.4e-10; MTCY270.06, 1.5e-09; MTCY21B4.13c, 2.8e-09; MTCY1A11.25c, 9.7e-09; MTCY06H11.11, 7.4e-08. FASTA best: Q50594 hypothetical 43.9 kDa protein opt: 243z-score: 313.2 E(): 1.9e-10; (45.4% identity in 97 aa overlap) - none - gi|15608056 fig|83332.1.peg.918 CDS NC_000962 1022085 1023866 3 + 1782 High-affinity choline uptake protein BetT Choline and Betaine Uptake and Betaine Biosynthesis gi|15608057 fig|83332.1.peg.919 CDS NC_000962 1024209 1024685 3 + 477 FIG032766: hypothetical protein CBSS-374931.9.peg.1048 gi|15608058 fig|83332.1.peg.920 CDS NC_000962 1024682 1025182 2 + 501 FIG001353: Acetyltransferase CBSS-374931.9.peg.1048 gi|15608059 fig|83332.1.peg.921 CDS NC_000962 1026814 1025495 -1 - 1320 hypothetical protein Rv0920c - none - gi|15608060 fig|83332.1.peg.922 CDS NC_000962 1027102 1027683 1 + 582 hypothetical protein Rv0921 - none - gi|15608061 fig|83332.1.peg.923 CDS NC_000962 1027683 1029335 3 + 1653 hypothetical protein Rv0922 - none - gi|15608062 fig|83332.1.peg.924 CDS NC_000962 1030575 1029511 -3 - 1065 hypothetical protein Rv0923c - none - gi|15608063 fig|83332.1.peg.925 CDS NC_000962 1031862 1030576 -3 - 1287 Manganese transport protein MntH - none - gi|15608064 fig|83332.1.peg.926 CDS NC_000962 1032631 1031894 -1 - 738 hypothetical protein Rv0925c - none - gi|15608065 fig|83332.1.peg.927 CDS NC_000962 1033784 1032708 -2 - 1077 hypothetical protein Rv0926c - none - gi|15608066 fig|83332.1.peg.928 CDS NC_000962 1034629 1033838 -1 - 792 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - none - gi|15608067 fig|83332.1.peg.929 CDS NC_000962 1034901 1036013 3 + 1113 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) High affinity phosphate transporter and control of PHO regulon;
PhoR-PhoB two-component regulatory system;
Phosphate metabolism gi|15608068 fig|83332.1.peg.930 CDS NC_000962 1036026 1037000 3 + 975 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) High affinity phosphate transporter and control of PHO regulon;
Phosphate metabolism gi|15608069 fig|83332.1.peg.931 CDS NC_000962 1036997 1037908 2 + 912 Phosphate transport system permease protein PstA (TC 3.A.1.7.1) High affinity phosphate transporter and control of PHO regulon;
Phosphate metabolism gi|15608070 fig|83332.1.peg.932 CDS NC_000962 1039912 1037918 -1 - 1995 (MTCY08D9.08), pknD, len: 664. Probable serine-threonine protein kinase. Related to many such proteinkinases particularly in N-terminal half. Fasta scores: Q11053 K08G_MYCTU PROBABLE SERINE/THREONINE-PROTEIN (626 aa) opt: 1398; E: 0; (49.3% identity in 540 aa overlap); and MTCY04C12.28,(566 aa) opt: 1270; E(): 0; (51.0% identity in 431 aa overlap) - none - gi|15608071 fig|83332.1.peg.933 CDS NC_000962 1041046 1039934 -1 - 1113 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) High affinity phosphate transporter and control of PHO regulon;
PhoR-PhoB two-component regulatory system;
Phosphate metabolism gi|15608072 fig|83332.1.peg.934 CDS NC_000962 1041262 1042092 1 + 831 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) High affinity phosphate transporter and control of PHO regulon;
Phosphate metabolism gi|15608073 fig|83332.1.peg.935 CDS NC_000962 1042113 1043237 3 + 1125 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) High affinity phosphate transporter and control of PHO regulon;
PhoR-PhoB two-component regulatory system;
Phosphate metabolism gi|15608074 fig|83332.1.peg.936 CDS NC_000962 1043297 1044313 2 + 1017 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) High affinity phosphate transporter and control of PHO regulon;
Phosphate metabolism gi|15608075 fig|83332.1.peg.937 CDS NC_000962 1044315 1045220 3 + 906 Phosphate transport system permease protein PstA (TC 3.A.1.7.1) High affinity phosphate transporter and control of PHO regulon;
Phosphate metabolism gi|15608076 fig|83332.1.peg.938 CDS NC_000962 1046018 1045197 -2 - 822 Ku domain protein Bacillus subtilis scratch - gjo;
DNA Repair Base Excision;
DNA ligases;
Nonhomologous End-Joining in Bacteria gi|15608077 fig|83332.1.peg.939 CDS NC_000962 1046134 1048413 1 + 2280 ATP-dependent DNA ligase (EC 6.5.1.1) clustered with Ku protein, LigD Bacillus subtilis scratch - gjo;
DNA Repair Base Excision;
DNA ligases;
Nonhomologous End-Joining in Bacteria gi|15608078 fig|83332.1.peg.940 CDS NC_000962 1048410 1050344 3 + 1935 Fumarylacetoacetase (EC 3.7.1.2) Pterin carbinolamine dehydratase gi|15608079 fig|83332.1.peg.941 CDS NC_000962 1051457 1050591 -2 - 867 hypothetical protein Rv0940c - none - gi|15608080 fig|83332.1.peg.942 CDS NC_000962 1052315 1051542 -2 - 774 hypothetical protein - none - gi|15608081 fig|83332.1.peg.943 CDS NC_000962 1052358 1052636 3 + 279 hypothetical protein Rv0942 - none - gi|15608082 fig|83332.1.peg.944 CDS NC_000962 1053734 1052694 -2 - 1041 hypothetical protein Rv0943c - none - gi|15608083 fig|83332.1.peg.945 CDS NC_000962 1053763 1054239 1 + 477 Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23) - none - gi|15608084 fig|83332.1.peg.946 CDS NC_000962 1054245 1055006 3 + 762 Oxidoreductase, short-chain dehydrogenase/reductase family (EC 1.1.1.-) CBSS-291331.3.peg.3674 gi|15608085 fig|83332.1.peg.947 CDS NC_000962 1056683 1055022 -2 - 1662 Glucose-6-phosphate isomerase (EC 5.3.1.9) Glycolysis and Gluconeogenesis gi|15608086 fig|83332.1.peg.948 CDS NC_000962 1057528 1057298 -1 - 231 Mycolyl transferase (EC 2.3.1.-), Antigen 85 complex C # fragment - none - gi|15608087 fig|83332.1.peg.949 CDS NC_000962 1057961 1057644 -2 - 318 Chorismate mutase I (EC 5.4.99.5) # AroHI Chorismate Synthesis;
Phenylalanine and Tyrosine Branches from Chorismate gi|15608088 fig|83332.1.peg.950 CDS NC_000962 1058258 1060573 2 + 2316 ATP-dependent DNA helicase UvrD/PcrA DNA repair, bacterial UvrD and related helicases gi|15608089 fig|83332.1.peg.951 CDS NC_000962 1061652 1060654 -3 - 999 Phage peptidoglycan binding endopeptidase - none - gi|15608090 fig|83332.1.peg.952 CDS NC_000962 1061962 1063125 1 + 1164 Succinyl-CoA ligase [ADP-forming] beta chain (EC 6.2.1.5) Dehydrogenase complexes;
Serine-glyoxylate cycle;
TCA Cycle gi|15608091 fig|83332.1.peg.953 CDS NC_000962 1063138 1064049 1 + 912 Succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5) Dehydrogenase complexes;
Serine-glyoxylate cycle;
TCA Cycle gi|15608092 fig|83332.1.peg.954 CDS NC_000962 1064960 1064112 -2 - 849 N5,N10-methylenetetrahydromethanopterin reductase-related protein, MSMEG5498 family - none - gi|15608093 fig|83332.1.peg.955 CDS NC_000962 1065125 1066036 2 + 912 34 kDa antigenic protein - none - gi|15608094 fig|83332.1.peg.956 CDS NC_000962 1066076 1067443 2 + 1368 FIG021574: Possible membrane protein related to de Novo purine biosynthesis - none - gi|15608095 fig|83332.1.peg.957 CDS NC_000962 1067559 1068206 3 + 648 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) 5-FCL-like protein;
De Novo Purine Biosynthesis;
Glutathione-regulated potassium-efflux system and associated functions gi|15608096 fig|83332.1.peg.958 CDS NC_000962 1068203 1069774 2 + 1572 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) 5-FCL-like protein;
De Novo Purine Biosynthesis;
De Novo Purine Biosynthesis gi|15608097 fig|83332.1.peg.959 CDS NC_000962 1069881 1071260 3 + 1380 Magnesium chelatase, subunit ChlI (EC 6.6.1.1) CBSS-336982.3.peg.1011 gi|15608098 fig|83332.1.peg.960 CDS NC_000962 1071253 1073271 1 + 2019 FIG019045: long form Mg-chelase associated protein with vWA domain CBSS-336982.3.peg.1011 gi|15608099 fig|83332.1.peg.961 CDS NC_000962 1073543 1073926 2 + 384 Toxin 1, PIN domain Toxin-Antitoxin MT1 gi|15608100 fig|83332.1.peg.962 CDS NC_000962 1074072 1074419 3 + 348 PROBABLE INTEGRAL MEMBRANE PROTEIN - none - gi|15608101 fig|83332.1.peg.963 CDS NC_000962 1075112 1074438 -2 - 675 hypothetical protein Rv0962c - none - gi|15608102 fig|83332.1.peg.964 CDS NC_000962 1076095 1075295 -1 - 801 hypothetical protein Rv0963c - none - gi|15608103 fig|83332.1.peg.965 CDS NC_000962 1076676 1076194 -3 - 483 hypothetical protein Rv0964c - none - gi|15608104 fig|83332.1.peg.966 CDS NC_000962 1077195 1076776 -3 - 420 hypothetical protein - none - gi|15608105 fig|83332.1.peg.967 CDS NC_000962 1077923 1077231 -2 - 693 hypothetical protein Rv0966c - none - gi|15608106 fig|83332.1.peg.968 CDS NC_000962 1077973 1078332 1 + 360 hypothetical protein Rv0967 - none - gi|15608107 fig|83332.1.peg.969 CDS NC_000962 1078389 1078685 3 + 297 hypothetical protein Rv0968 - none - gi|15608108 fig|83332.1.peg.970 CDS NC_000962 1078741 1081053 1 + 2313 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) Copper Transport System;
Copper homeostasis;
Terminal cytochrome C oxidases gi|15608109 fig|83332.1.peg.971 CDS NC_000962 1081050 1081682 3 + 633 hypothetical protein Rv0970 - none - gi|15608110 fig|83332.1.peg.972 CDS NC_000962 1082582 1081773 -2 - 810 Methylglutaconyl-CoA hydratase (EC 4.2.1.18) HMG CoA Synthesis;
Leucine Degradation and HMG-CoA Metabolism gi|15608111 fig|83332.1.peg.973 CDS NC_000962 1083748 1082582 -1 - 1167 Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.8.1) HMG CoA Synthesis;
Leucine Degradation and HMG-CoA Metabolism gi|15608112 fig|83332.1.peg.974 CDS NC_000962 1085748 1083745 -3 - 2004 Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4) HMG CoA Synthesis;
Leucine Degradation and HMG-CoA Metabolism;
Serine-glyoxylate cycle gi|15608113 fig|83332.1.peg.975 CDS NC_000962 1087343 1085754 -2 - 1590 Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4) HMG CoA Synthesis;
Leucine Degradation and HMG-CoA Metabolism;
Serine-glyoxylate cycle gi|15608114 fig|83332.1.peg.976 CDS NC_000962 1088494 1087346 -1 - 1149 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) HMG CoA Synthesis;
Leucine Degradation and HMG-CoA Metabolism gi|15608115 fig|83332.1.peg.977 CDS NC_000962 1090173 1088491 -3 - 1683 hypothetical protein Rv0976c - none - gi|15608116 fig|83332.1.peg.978 CDS NC_000962 1090371 1093142 3 + 2772 PE family protein - none - gi|15608117 fig|83332.1.peg.979 CDS NC_000962 1094354 1093359 -2 - 996 PE_PGRS family protein - none - gi|15608118 fig|83332.1.peg.980 CDS NC_000962 1094994 1094668 -3 - 327 hypothetical protein Rv0979c - none - gi|15608119 fig|83332.1.peg.981 CDS NC_000962 1096449 1095076 -3 - 1374 PE_PGRS family protein - none - gi|15608120 fig|83332.1.peg.982 CDS NC_000962 1096814 1097506 2 + 693 Mycobacterial persistence regulator MprA (Two component response transcriptional regulatory protein) Involvement of a novel heat shock protein (Hsp22.5) in mycobacterial persistence gi|15608121 fig|83332.1.peg.983 CDS NC_000962 1097506 1099020 1 + 1515 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) Involvement of a novel heat shock protein (Hsp22.5) in mycobacterial persistence gi|15608122 fig|83332.1.peg.984 CDS NC_000962 1099064 1100458 2 + 1395 Heat shock protein HtrA Involvement of a novel heat shock protein (Hsp22.5) in mycobacterial persistence gi|15608123 fig|83332.1.peg.985 CDS NC_000962 1100458 1101003 1 + 546 Molybdenum cofactor biosynthesis protein MoaB Involvement of a novel heat shock protein (Hsp22.5) in mycobacterial persistence;
Molybdenum cofactor biosynthesis;
ar-104-EC Molybdenum cofactor biosynthesis moaABCDE gi|15608124 fig|83332.1.peg.986 CDS NC_000962 1101478 1101023 -1 - 456 Large-conductance mechanosensitive channel Glutathione-regulated potassium-efflux system and associated functions;
Involvement of a novel heat shock protein (Hsp22.5) in mycobacterial persistence;
Potassium homeostasis gi|15608125 fig|83332.1.peg.987 CDS NC_000962 1101801 1102547 3 + 747 AttE component of AttEFGH ABC transport system AttEFGH ABC Transport System gi|15608126 fig|83332.1.peg.988 CDS NC_000962 1102540 1105107 1 + 2568 AttF component of AttEFGH ABC transport system / AttG component of AttEFGH ABC transport system AttEFGH ABC Transport System;
AttEFGH ABC Transport System gi|15608127 fig|83332.1.peg.989 CDS NC_000962 1105114 1106274 1 + 1161 AttH component of AttEFGH ABC transport system AttEFGH ABC Transport System gi|15608128 fig|83332.1.peg.990 CDS NC_000962 1107380 1106403 -2 - 978 Octaprenyl diphosphate synthase (EC 2.5.1.90) / Dimethylallyltransferase (EC 2.5.1.1) / (2E,6E)-farnesyl diphosphate synthase (EC 2.5.1.10) / Geranylgeranyl diphosphate synthase (EC 2.5.1.29) Carotenoids;
Carotenoids;
Isoprenoid Biosynthesis;
Isoprenoid Biosynthesis;
Isoprenoinds for Quinones;
Isoprenoinds for Quinones;
Isoprenoinds for Quinones;
Isoprenoinds for Quinones;
Polyprenyl Diphosphate Biosynthesis;
Polyprenyl Diphosphate Biosynthesis;
Polyprenyl Diphosphate Biosynthesis gi|15608129 fig|83332.1.peg.991 CDS NC_000962 1108097 1107441 -2 - 657 Heat shock protein 22.5 (Hsp22.5) Involvement of a novel heat shock protein (Hsp22.5) in mycobacterial persistence gi|15608130 fig|83332.1.peg.992 CDS NC_000962 1108502 1108170 -2 - 333 Putative regulatory protein, FmdB family Involvement of a novel heat shock protein (Hsp22.5) in mycobacterial persistence gi|15608131 fig|83332.1.peg.993 CDS NC_000962 1109169 1108576 -3 - 594 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) 5-FCL-like protein;
Folate Biosynthesis;
Involvement of a novel heat shock protein (Hsp22.5) in mycobacterial persistence;
One-carbon metabolism by tetrahydropterines;
Serine-glyoxylate cycle gi|15608132 fig|83332.1.peg.994 CDS NC_000962 1109270 1110190 2 + 921 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) Glycogen metabolism;
Involvement of a novel heat shock protein (Hsp22.5) in mycobacterial persistence;
Ribosome post-transcriptional modification and chromosomal segregation cluster gi|15608133 fig|83332.1.peg.995 CDS NC_000962 1110267 1111547 3 + 1281 Molybdopterin biosynthesis protein MoeA Involvement of a novel heat shock protein (Hsp22.5) in mycobacterial persistence;
Molybdenum cofactor biosynthesis gi|15608134 fig|83332.1.peg.996 CDS NC_000962 1111610 1112221 2 + 612 Ribosomal-protein-S5p-alanine acetyltransferase Involvement of a novel heat shock protein (Hsp22.5) in mycobacterial persistence;
Ribosomal protein S5p acylation;
Ribosome biogenesis bacterial gi|15608135 fig|83332.1.peg.997 CDS NC_000962 1112382 1113458 3 + 1077 FIG037137: Putative conserved transmembrane protein Involvement of a novel heat shock protein (Hsp22.5) in mycobacterial persistence gi|15608136 fig|83332.1.peg.998 CDS NC_000962 1114291 1114722 1 + 432 hypothetical protein Rv0997 - none - gi|15608137 fig|83332.1.peg.999 CDS NC_000962 1114746 1115747 3 + 1002 hypothetical protein Rv0998 - none - gi|15608138 fig|83332.1.peg.1000 CDS NC_000962 1115765 1116523 2 + 759 hypothetical protein Rv0999 - none - gi|15608139 fig|83332.1.peg.1001 CDS NC_000962 1117146 1116529 -3 - 618 Alkylated DNA repair protein - none - gi|15611069 fig|83332.1.peg.1002 CDS NC_000962 1116649 1117179 1 + 531 hypothetical protein Rv1000 - none - gi|15608140 fig|83332.1.peg.1003 CDS NC_000962 1117183 1118391 1 + 1209 Arginine deiminase (EC 3.5.3.6) Arginine Deiminase Pathway;
Arginine and Ornithine Degradation gi|15608141 fig|83332.1.peg.1004 CDS NC_000962 1119937 1118426 -1 - 1512 hypothetical protein Rv1002c - none - gi|15608142 fig|83332.1.peg.1005 CDS NC_000962 1120020 1120877 3 + 858 rRNA small subunit methyltransferase I 16S rRNA modification within P site of ribosome;
Heat shock dnaK gene cluster extended gi|15608143 fig|83332.1.peg.1006 CDS NC_000962 1122146 1120887 -2 - 1260 elastin - none - gi|15608144 fig|83332.1.peg.1007 CDS NC_000962 1123596 1122220 -3 - 1377 Para-aminobenzoate synthase, aminase component (EC 2.6.1.85) # PabAa Chorismate: Intermediate for synthesis of Tryptophan, PAPA antibiotics, PABA, 3-hydroxyanthranilate and more.;
Folate Biosynthesis;
Tryptophan synthesis gi|15608145 fig|83332.1.peg.1008 CDS NC_000962 1123712 1125415 2 + 1704 hypothetical protein Rv1006 - none - gi|15608146 fig|83332.1.peg.1009 CDS NC_000962 1127001 1125442 -3 - 1560 Methionyl-tRNA synthetase (EC 6.1.1.10) tRNA aminoacylation, Met gi|15608147 fig|83332.1.peg.1010 CDS NC_000962 1127087 1127881 2 + 795 Putative deoxyribonuclease YcfH YcfH gi|15608148 fig|83332.1.peg.1011 CDS NC_000962 1128089 1129177 2 + 1089 Probable resuscitation-promoting factor rpfB - none - gi|15608149 fig|83332.1.peg.1012 CDS NC_000962 1129150 1130103 1 + 954 SSU rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase (EC 2.1.1.182) RNA methylation;
Ribosome biogenesis bacterial gi|15608150 fig|83332.1.peg.1013 CDS NC_000962 1130189 1131109 2 + 921 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (EC 2.7.1.148) Isoprenoid Biosynthesis;
Nonmevalonate Branch of Isoprenoid Biosynthesis gi|15608151 fig|83332.1.peg.1014 CDS NC_000962 1131126 1131419 3 + 294 hypothetical protein Rv1012 - none - gi|15608152 fig|83332.1.peg.1015 CDS NC_000962 1131623 1133257 2 + 1635 Putative polyketide synthase pks16 - none - gi|15608153 fig|83332.1.peg.1016 CDS NC_000962 1133906 1133331 -2 - 576 Peptidyl-tRNA hydrolase (EC 3.1.1.29) Cell division-ribosomal stress proteins cluster;
Sporulation-associated proteins with broader functions;
Transcription repair cluster;
Translation termination factors bacterial gi|15608154 fig|83332.1.peg.1017 CDS NC_000962 1134566 1133919 -2 - 648 LSU ribosomal protein L25p Ribosome LSU bacterial;
Transcription repair cluster gi|15608155 fig|83332.1.peg.1018 CDS NC_000962 1135463 1134783 -2 - 681 Lipoprotein LpqT Transcription repair cluster gi|15608156 fig|83332.1.peg.1019 CDS NC_000962 1136479 1135499 -1 - 981 Ribose-phosphate pyrophosphokinase (EC 2.7.6.1) De Novo Purine Biosynthesis;
Pentose phosphate pathway;
Transcription repair cluster gi|15608157 fig|83332.1.peg.1020 CDS NC_000962 1138058 1136571 -2 - 1488 N-acetylglucosamine-1-phosphate uridyltransferase (EC 2.7.7.23) / Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157) Peptidoglycan Biosynthesis;
Peptidoglycan Biosynthesis;
Transcription repair cluster;
Transcription repair cluster;
UDP-N-acetylmuramate from Fructose-6-phosphate Biosynthesis;
UDP-N-acetylmuramate from Fructose-6-phosphate Biosynthesis gi|15608158 fig|83332.1.peg.1021 CDS NC_000962 1138313 1138906 2 + 594 Transcriptional regulator, TetR family - none - gi|15608159 fig|83332.1.peg.1022 CDS NC_000962 1138965 1142669 3 + 3705 Transcription-repair coupling factor Cell division-ribosomal stress proteins cluster;
Transcription factors bacterial;
Transcription repair cluster gi|15608160 fig|83332.1.peg.1023 CDS NC_000962 1142669 1143646 2 + 978 Nucleoside triphosphate pyrophosphohydrolase MazG (EC 3.6.1.8) Nucleoside triphosphate pyrophosphohydrolase MazG gi|15608161 fig|83332.1.peg.1024 CDS NC_000962 1143734 1144465 2 + 732 PUTATIVE CONSERVED LIPOPROTEIN LPQU - none - gi|15608162 fig|83332.1.peg.1025 CDS NC_000962 1144562 1145851 2 + 1290 Enolase (EC 4.2.1.11) Dehydrogenase complexes;
Glycolysis and Gluconeogenesis;
Serine-glyoxylate cycle gi|15608163 fig|83332.1.peg.1026 CDS NC_000962 1145856 1146542 3 + 687 Cell division protein DivIC (FtsB), stabilizes FtsL against RasP cleavage Bacterial Cell Division;
Bacterial Cytoskeleton;
Cell division-ribosomal stress proteins cluster;
Dehydrogenase complexes;
Possible new toxin-antitoxin system including DivIC;
Stationary phase repair cluster gi|15608164 fig|83332.1.peg.1027 CDS NC_000962 1146559 1147026 1 + 468 FIG004853: possible toxin to DivIC Possible new toxin-antitoxin system including DivIC gi|15608165 fig|83332.1.peg.1028 CDS NC_000962 1147017 1147976 3 + 960 Exopolyphosphatase (EC 3.6.1.11) High affinity phosphate transporter and control of PHO regulon;
Phosphate metabolism;
Polyphosphate gi|15608166 fig|83332.1.peg.1029 CDS NC_000962 1149105 1148425 -3 - 681 DNA-binding response regulator KdpE - none - gi|15608167 fig|83332.1.peg.1030 CDS NC_000962 1151684 1149102 -2 - 2583 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) Involvement of a novel heat shock protein (Hsp22.5) in mycobacterial persistence;
Potassium homeostasis gi|15608168 fig|83332.1.peg.1031 CDS NC_000962 1152010 1153725 1 + 1716 Potassium-transporting ATPase A chain (EC 3.6.3.12) (TC 3.A.3.7.1) Potassium homeostasis gi|15608169 fig|83332.1.peg.1032 CDS NC_000962 1153722 1155851 3 + 2130 Potassium-transporting ATPase B chain (EC 3.6.3.12) (TC 3.A.3.7.1) Potassium homeostasis gi|15608170 fig|83332.1.peg.1033 CDS NC_000962 1155851 1156420 2 + 570 Potassium-transporting ATPase C chain (EC 3.6.3.12) (TC 3.A.3.7.1) Potassium homeostasis gi|15608171 fig|83332.1.peg.1034 CDS NC_000962 1157953 1156424 -1 - 1530 hypothetical protein Rv1032c - none - gi|15608172 fig|83332.1.peg.1035 CDS NC_000962 1158734 1157961 -2 - 774 hypothetical protein Rv1033c - none - gi|15608173 fig|83332.1.peg.1036 CDS NC_000962 1159305 1158916 -3 - 390 hypothetical protein Rv1034c - none - gi|15608174 fig|83332.1.peg.1037 CDS NC_000962 1160059 1159373 -1 - 687 hypothetical protein Rv1035c - none - gi|15608175 fig|83332.1.peg.1038 CDS NC_000962 1160431 1160093 -1 - 339 Mobile element protein - none - gi|15608176 fig|83332.1.peg.1039 CDS NC_000962 1160826 1160542 -3 - 285 hypothetical protein Rv1037c - none - gi|15608177 fig|83332.1.peg.1040 CDS NC_000962 1161149 1160853 -2 - 297 hypothetical protein Rv1038c - none - gi|15608178 fig|83332.1.peg.1041 CDS NC_000962 1162470 1161295 -3 - 1176 PPE family protein CBSS-164757.7.peg.5020 gi|15608179 fig|83332.1.peg.1042 CDS NC_000962 1163374 1162547 -1 - 828 PE_PGRS family protein - none - gi|15608180 fig|83332.1.peg.1043 CDS NC_000962 1165433 1164570 -2 - 864 Mobile element protein - none - gi|15608181 fig|83332.1.peg.1044 CDS NC_000962 1165497 1165090 -3 - 408 Mobile element protein - none - gi|15608182 fig|83332.1.peg.1045 CDS NC_000962 1166804 1165779 -2 - 1026 hypothetical protein Rv1043c - none - gi|15608183 fig|83332.1.peg.1046 CDS NC_000962 1167051 1167674 3 + 624 hypothetical protein Rv1044 - none - gi|15608184 fig|83332.1.peg.1047 CDS NC_000962 1167671 1168552 2 + 882 hypothetical protein Rv1045 - none - gi|15608185 fig|83332.1.peg.1048 CDS NC_000962 1169421 1168702 -3 - 720 hypothetical protein Rv1046c - none - gi|15608186 fig|83332.1.peg.1049 CDS NC_000962 1169421 1170668 3 + 1248 Mobile element protein - none - gi|15608187 fig|83332.1.peg.1050 CDS NC_000962 1172151 1171036 -3 - 1116 hypothetical protein Rv1048c - none - gi|15608188 fig|83332.1.peg.1051 CDS NC_000962 1172384 1172830 2 + 447 Transcriptional regulator, MarR family - none - gi|15608189 fig|83332.1.peg.1052 CDS NC_000962 1172879 1173784 2 + 906 hypothetical protein Rv1050 - none - gi|15608190 fig|83332.1.peg.1053 CDS NC_000962 1174698 1173943 -3 - 756 hypothetical protein Rv1051c - none - gi|15608191 fig|83332.1.peg.1054 CDS NC_000962 1175721 1176110 3 + 390 hypothetical protein Rv1052 - none - gi|15608192 fig|83332.1.peg.1055 CDS NC_000962 1176284 1176009 -2 - 276 Mobile element protein - none - gi|15608193 fig|83332.1.peg.1056 CDS NC_000962 1176926 1177129 2 + 204 Integrase - none - gi|15608194 fig|83332.1.peg.1057 CDS NC_000962 1177135 1177371 1 + 237 Integrase - none - gi|15608195 fig|83332.1.peg.1058 CDS NC_000962 1177626 1178390 3 + 765 hypothetical protein Rv1056 - none - gi|15608196 fig|83332.1.peg.1059 CDS NC_000962 1179394 1180575 1 + 1182 hypothetical protein Rv1057 - none - gi|15608197 fig|83332.1.peg.1060 CDS NC_000962 1180682 1182313 2 + 1632 (MTV017.11), len: 543. Probable fatty acidCoA-ligase similar to MEDIUM-CHAIN-FATTY-ACID--COA LIGASE (546 aa) (EC6.2.1.-) and 4-COUMARATE-COA LIGASE (EC 6.2.1.12). ContainsPS00455 Putative AMP-binding domain signature. FASTA scores: sp|Q00594|ALKK_PSEOL MEDIUM-CHAIN-FATTY-ACID--COA LIGA(546 aa) opt: 1468 z-score: 1731.7 E(): 0; 41.1%identity in538 aa overlap. TBparse score is 0.916 - none - gi|15608198 fig|83332.1.peg.1061 CDS NC_000962 1182389 1183453 2 + 1065 hypothetical protein Rv1059 - none - gi|15608199 fig|83332.1.peg.1062 CDS NC_000962 1183506 1183979 3 + 474 hypothetical protein Rv1060 - none - gi|15608200 fig|83332.1.peg.1063 CDS NC_000962 1184013 1184876 3 + 864 hypothetical protein Rv1061 - none - gi|15608201 fig|83332.1.peg.1064 CDS NC_000962 1184881 1185738 1 + 858 hypothetical protein Rv1062 - none - gi|15608202 fig|83332.1.peg.1065 CDS NC_000962 1186821 1185739 -3 - 1083 UPF0028 protein YchK Broadly distributed proteins not in subsystems gi|15608203 fig|83332.1.peg.1066 CDS NC_000962 1187321 1186902 -2 - 420 (MTV017.17c), len: 139. Unknown but probably lipoprotein. Has N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. TBparse score is 0.912 - none - gi|15608204 fig|83332.1.peg.1067 CDS NC_000962 1187433 1187999 3 + 567 hypothetical protein Rv1065 - none - gi|15608205 fig|83332.1.peg.1068 CDS NC_000962 1187996 1188391 2 + 396 hypothetical protein Rv1066 - none - gi|15608206 fig|83332.1.peg.1069 CDS NC_000962 1190422 1188419 -1 - 2004 (MTV017.20c), len: 667. Member of M. tuberculosis PE-family, Gly-, Ala-rich PGRS subfamily. ContainsPS00583 pfkB family of carbohydrate kinases signature 1, probably fortuitous. FASTA scores: AL0091|MTV004_44 (731 aa)opt: 2227 z-score: 1261.4 E(): 0; 55.6% identity in 710aaoverlap. TBparse score is 0.837 - none - gi|15608207 fig|83332.1.peg.1070 CDS NC_000962 1192146 1190755 -3 - 1392 PE-PGRS FAMILY PROTEIN - none - gi|15608208 fig|83332.1.peg.1071 CDS NC_000962 1194271 1192508 -1 - 1764 Predicted membrane protein (DUF2319) - none - gi|15608209 fig|83332.1.peg.1072 CDS NC_000962 1195041 1194268 -3 - 774 Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) Valine degradation gi|15608210 fig|83332.1.peg.1073 CDS NC_000962 1196090 1195053 -2 - 1038 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) Valine degradation gi|15608211 fig|83332.1.peg.1074 CDS NC_000962 1196277 1197113 3 + 837 PROBABLE CONSERVED TRANSMEMBRANE PROTEIN - none - gi|15608212 fig|83332.1.peg.1075 CDS NC_000962 1197229 1198080 1 + 852 hypothetical protein Rv1073 - none - gi|15608213 fig|83332.1.peg.1076 CDS NC_000962 1199371 1198154 -1 - 1218 3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9) Acetyl-CoA fermentation to Butyrate;
Biotin biosynthesis;
Biotin synthesis cluster;
Butanol Biosynthesis;
CBSS-246196.1.peg.364;
Fatty acid metabolism cluster;
Isoleucine degradation;
Isoprenoid Biosynthesis;
Polyhydroxybutyrate metabolism;
Polyhydroxybutyrate metabolism;
Serine-glyoxylate cycle;
Serine-glyoxylate cycle gi|15608214 fig|83332.1.peg.1077 CDS NC_000962 1200368 1199424 -2 - 945 hypothetical protein Rv1075c - none - gi|15608215 fig|83332.1.peg.1078 CDS NC_000962 1200765 1201658 3 + 894 esterase - none - gi|15608216 fig|83332.1.peg.1079 CDS NC_000962 1201715 1203109 2 + 1395 Cystathionine beta-synthase (EC 4.2.1.22) Cysteine Biosynthesis;
Glycine and Serine Utilization;
Methionine Biosynthesis;
Methionine Degradation gi|15608217 fig|83332.1.peg.1080 CDS NC_000962 1203311 1204033 2 + 723 Proline-rich antigen homolog - none - gi|15608218 fig|83332.1.peg.1081 CDS NC_000962 1204065 1205231 3 + 1167 Cystathionine gamma-lyase (EC 4.4.1.1) Cysteine Biosynthesis;
Glycine and Serine Utilization;
Methionine Biosynthesis;
Methionine Degradation gi|15608219 fig|83332.1.peg.1082 CDS NC_000962 1205796 1205302 -3 - 495 Transcription elongation factor GreA Transcription factors bacterial gi|15608220 fig|83332.1.peg.1083 CDS NC_000962 1206416 1205982 -2 - 435 hypothetical protein Rv1081c - none - gi|15608221 fig|83332.1.peg.1084 CDS NC_000962 1206518 1207384 2 + 867 Mycothiol S-conjugate amidase Mca Glutathione analogs: mycothiol gi|15608222 fig|83332.1.peg.1085 CDS NC_000962 1207381 1207647 1 + 267 hypothetical protein Rv1083 - none - gi|15608223 fig|83332.1.peg.1086 CDS NC_000962 1207634 1209655 2 + 2022 Thymidylate kinase (EC 2.7.4.9) pyrimidine conversions gi|15608224 fig|83332.1.peg.1087 CDS NC_000962 1210482 1209754 -3 - 729 COG1272: Predicted membrane protein hemolysin III homolog - none - gi|15608225 fig|83332.1.peg.1088 CDS NC_000962 1210593 1211381 3 + 789 (2E,6Z)-farnesyl diphosphate synthase (EC 2.5.1.68) Isoprenoinds for Quinones;
Polyprenyl Diphosphate Biosynthesis gi|15608226 fig|83332.1.peg.1089 CDS NC_000962 1211558 1213861 2 + 2304 PE family protein - none - gi|15608227 fig|83332.1.peg.1090 CDS NC_000962 1214511 1214945 3 + 435 (MTV017.41), len: 144. Member of Mycobacterium tuberculosis PE family, similar to many others e.g. MTCI418B_6 (487 aa) except it appears to be frameshifted around codon 84. No error to account for frameshift could be found. FASTA scores: gp|Z96071|MTCI418B_6 Mycobacterium tuberculosis cosmid (487 aa) opt: 318 z-score: 383.5 E(): 7.3e-14; 60.9% identity in 87 aa overlap. TBparse score is 0.943 - none - gi|15608228 fig|83332.1.peg.1091 CDS NC_000962 1214767 1215129 1 + 363 PE family protein - none - gi|15608229 fig|83332.1.peg.1092 CDS NC_000962 1215597 1216052 3 + 456 hypothetical protein Rv1090 - none - gi|15608230 fig|83332.1.peg.1093 CDS NC_000962 1216467 1219028 3 + 2562 PE family protein - none - gi|15608231 fig|83332.1.peg.1094 CDS NC_000962 1220184 1219246 -3 - 939 Pantothenate kinase (EC 2.7.1.33) Coenzyme A Biosynthesis gi|15608232 fig|83332.1.peg.1095 CDS NC_000962 1220572 1221852 1 + 1281 Serine hydroxymethyltransferase 1 (EC 2.1.2.1) Serine Biosynthesis gi|15608233 fig|83332.1.peg.1096 CDS NC_000962 1221957 1222784 3 + 828 Acyl-[acyl-carrier protein] desaturase DesA2 (EC 1.14.19.2) - none - gi|15608234 fig|83332.1.peg.1097 CDS NC_000962 1222995 1224296 3 + 1302 Predicted ATPase related to phosphate starvation-inducible protein PhoH Phosphate metabolism gi|15608235 fig|83332.1.peg.1098 CDS NC_000962 1224383 1225258 2 + 876 Possible glycosyl hydrolase (EC 3.-.-.-) - none - gi|15608236 fig|83332.1.peg.1099 CDS NC_000962 1226142 1225261 -3 - 882 hypothetical protein Rv1097c - none - gi|15608237 fig|83332.1.peg.1100 CDS NC_000962 1227563 1226139 -2 - 1425 Fumarate hydratase class II (EC 4.2.1.2) TCA Cycle gi|15608238 fig|83332.1.peg.1101 CDS NC_000962 1228580 1227594 -2 - 987 Fructose-1,6-bisphosphatase, GlpX type (EC 3.1.3.11) Glycolysis and Gluconeogenesis gi|15608239 fig|83332.1.peg.1102 CDS NC_000962 1228681 1229382 1 + 702 hypothetical protein Rv1100 - none - gi|15608240 fig|83332.1.peg.1103 CDS NC_000962 1230546 1229389 -3 - 1158 hypothetical protein Rv1101c - none - gi|15608241 fig|83332.1.peg.1104 CDS NC_000962 1230969 1230658 -3 - 312 Death on curing protein, Doc toxin Phd-Doc, YdcE-YdcD toxin-antitoxin (programmed cell death) systems gi|15608242 fig|83332.1.peg.1105 CDS NC_000962 1231289 1230969 -2 - 321 Prevent host death protein, Phd antitoxin Phd-Doc, YdcE-YdcD toxin-antitoxin (programmed cell death) systems gi|15608243 fig|83332.1.peg.1106 CDS NC_000962 1231299 1231988 3 + 690 hypothetical protein Rv1104 - none - gi|15608244 fig|83332.1.peg.1107 CDS NC_000962 1232282 1232824 2 + 543 hypothetical protein Rv1105 - none - gi|15608245 fig|83332.1.peg.1108 CDS NC_000962 1233954 1232842 -3 - 1113 hypothetical protein Rv1106c - none - gi|15608246 fig|83332.1.peg.1109 CDS NC_000962 1234221 1233964 -3 - 258 Exodeoxyribonuclease VII small subunit (EC 3.1.11.6) DNA repair, bacterial;
Purine salvage cluster gi|15608247 fig|83332.1.peg.1110 CDS NC_000962 1235458 1234211 -1 - 1248 Exodeoxyribonuclease VII large subunit (EC 3.1.11.6) DNA repair, bacterial;
Purine salvage cluster gi|15608248 fig|83332.1.peg.1111 CDS NC_000962 1236093 1235455 -3 - 639 hypothetical protein Rv1109c - none - gi|15608249 fig|83332.1.peg.1112 CDS NC_000962 1236183 1237190 3 + 1008 4-hydroxy-3-methylbut-2-enyl diphosphate reductase (EC 1.17.1.2) Isoprenoid Biosynthesis;
Nonmevalonate Branch of Isoprenoid Biosynthesis gi|15608250 fig|83332.1.peg.1113 CDS NC_000962 1238121 1237207 -3 - 915 hypothetical protein Rv1111c - none - gi|15608251 fig|83332.1.peg.1114 CDS NC_000962 1238253 1239326 3 + 1074 GTP-binding and nucleic acid-binding protein YchF Universal GTPases gi|15608252 fig|83332.1.peg.1115 CDS NC_000962 1239414 1239611 3 + 198 hypothetical protein Rv1113 - none - gi|15608253 fig|83332.1.peg.1116 CDS NC_000962 1239608 1239982 2 + 375 PIN domain protein - none - gi|15608254 fig|83332.1.peg.1117 CDS NC_000962 1240185 1240883 3 + 699 hypothetical protein Rv1115 - none - gi|15608255 fig|83332.1.peg.1118 CDS NC_000962 1241001 1241186 3 + 186 hypothetical protein Rv1116 - none - gi|15608256 fig|83332.1.peg.1119 CDS NC_000962 1241631 1241954 3 + 324 hypothetical protein Rv1117 - none - gi|15608257 fig|83332.1.peg.1120 CDS NC_000962 1242829 1241969 -1 - 861 hypothetical protein Rv1118c - none - gi|15608258 fig|83332.1.peg.1121 CDS NC_000962 1243011 1242862 -3 - 150 hypothetical protein Rv1119c - none - gi|15608259 fig|83332.1.peg.1122 CDS NC_000962 1243502 1243008 -2 - 495 Adenylate cyclase (EC 4.6.1.1) - none - gi|15608260 fig|83332.1.peg.1123 CDS NC_000962 1243705 1245105 1 + 1401 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) Glycolysis and Gluconeogenesis;
Pentose phosphate pathway gi|15608261 fig|83332.1.peg.1124 CDS NC_000962 1245127 1246149 1 + 1023 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) Pentose phosphate pathway gi|15608262 fig|83332.1.peg.1125 CDS NC_000962 1247050 1246142 -1 - 909 POSSIBLE PEROXIDASE BPOB (NON-HAEM PEROXIDASE) - none - gi|15608263 fig|83332.1.peg.1126 CDS NC_000962 1247125 1248075 1 + 951 (MTCY22G8.13), len: 316. ephC, Similar to Q42566epoxide hydrolase (321 aa) from Arabidopsis thaliana, fastascores; opt: 298 z-score: 356.0 E(): 8.2e-13, 27.6% identity in 333 aa overlap. Similar to other M. tuberculosishydrolaseseg. MTCY09F9.26c (26.7% identity in 333 aa overlap) - none - gi|15608264 fig|83332.1.peg.1127 CDS NC_000962 1248080 1249324 2 + 1245 hypothetical protein Rv1125 - none - gi|15608265 fig|83332.1.peg.1128 CDS NC_000962 1249933 1249328 -1 - 606 hypothetical protein Rv1126c - none - gi|15608266 fig|83332.1.peg.1129 CDS NC_000962 1251402 1249930 -3 - 1473 Pyruvate,phosphate dikinase (EC 2.7.9.1) Glycolysis and Gluconeogenesis;
Pyruvate metabolism I: anaplerotic reactions, PEP gi|15608267 fig|83332.1.peg.1130 CDS NC_000962 1252970 1251615 -2 - 1356 hypothetical protein Rv1128c - none - gi|15608268 fig|83332.1.peg.1131 CDS NC_000962 1254532 1253072 -1 - 1461 XRE family transcriptional regulator MSMEG_6643 - none - gi|15608269 fig|83332.1.peg.1132 CDS NC_000962 1254553 1256133 1 + 1581 2-methylcitrate dehydratase (EC 4.2.1.79) Methylcitrate cycle;
Propionate-CoA to Succinate Module gi|15608270 fig|83332.1.peg.1133 CDS NC_000962 1256130 1257311 3 + 1182 2-methylcitrate synthase (EC 2.3.3.5) Methylcitrate cycle;
Propionate-CoA to Succinate Module gi|15608271 fig|83332.1.peg.1134 CDS NC_000962 1257323 1259053 2 + 1731 hypothetical protein Rv1132 - none - gi|15608272 fig|83332.1.peg.1135 CDS NC_000962 1261344 1259065 -3 - 2280 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) Methionine Biosynthesis gi|15608273 fig|83332.1.peg.1136 CDS NC_000962 1261920 1262156 3 + 237 hypothetical protein Rv1134 - none - gi|15608274 fig|83332.1.peg.1137 CDS NC_000962 1264126 1262270 -1 - 1857 PE family protein - none - gi|15608275 fig|83332.1.peg.1138 CDS NC_000962 1264604 1264945 2 + 342 hypothetical protein Rv1136 - none - gi|15608276 fig|83332.1.peg.1139 CDS NC_000962 1265453 1265085 -2 - 369 hypothetical protein Rv1137c - none - gi|15608277 fig|83332.1.peg.1140 CDS NC_000962 1266486 1265470 -3 - 1017 hypothetical protein Rv1138c - none - gi|15608278 fig|83332.1.peg.1141 CDS NC_000962 1266983 1266483 -2 - 501 hypothetical protein Rv1139c - none - gi|15608279 fig|83332.1.peg.1142 CDS NC_000962 1267345 1268193 1 + 849 hypothetical protein Rv1140 - none - gi|15608280 fig|83332.1.peg.1143 CDS NC_000962 1269007 1268201 -1 - 807 Enoyl-CoA hydratase (EC 4.2.1.17) Acetyl-CoA fermentation to Butyrate;
Butanol Biosynthesis;
Fatty acid metabolism cluster;
Isoleucine degradation;
Polyhydroxybutyrate metabolism;
Valine degradation gi|15608281 fig|83332.1.peg.1144 CDS NC_000962 1269956 1269150 -2 - 807 Enoyl-CoA hydratase (EC 4.2.1.17) Acetyl-CoA fermentation to Butyrate;
Butanol Biosynthesis;
Fatty acid metabolism cluster;
Isoleucine degradation;
Polyhydroxybutyrate metabolism;
Valine degradation gi|15608282 fig|83332.1.peg.1145 CDS NC_000962 1270060 1271142 1 + 1083 Alpha-methylacyl-CoA racemase (EC 5.1.99.4) - none - gi|15608283 fig|83332.1.peg.1146 CDS NC_000962 1271154 1271906 3 + 753 hypothetical protein Rv1144 - none - gi|15608284 fig|83332.1.peg.1147 CDS NC_000962 1272421 1273332 1 + 912 hypothetical protein Rv1145 - none - gi|15608285 fig|83332.1.peg.1148 CDS NC_000962 1273353 1274765 3 + 1413 hypothetical protein Rv1146 - none - gi|15608286 fig|83332.1.peg.1149 CDS NC_000962 1274898 1275548 3 + 651 hypothetical protein Rv1147 - none - gi|15608287 fig|83332.1.peg.1150 CDS NC_000962 1277746 1276298 -1 - 1449 hypothetical protein Rv1148c - none - gi|15608288 fig|83332.1.peg.1151 CDS NC_000962 1277891 1278298 2 + 408 Mobile element protein - none - gi|15608289 fig|83332.1.peg.1152 CDS NC_000962 1278267 1278818 3 + 552 Mobile element protein - none - gi|15608290 fig|83332.1.peg.1153 CDS NC_000962 1279615 1278902 -1 - 714 NAD-dependent protein deacetylase of SIR2 family NAD and NADP cofactor biosynthesis global;
Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate;
Redox-dependent regulation of nucleus processes;
dNTP triphosphohydrolase protein family gi|15608291 fig|83332.1.peg.1154 CDS NC_000962 1279653 1280018 3 + 366 Transcriptional regulator, GntR family - none - gi|15608292 fig|83332.1.peg.1155 CDS NC_000962 1280844 1279996 -3 - 849 (MTCI65.20c), len: 282. Similar to O-methyl transferase involved in tetracenomycin (polyketide) synthesis in Streptomyces glaucescens (EC 2.1.1.-). FASTA scores: TCMP_STRGA (P39887) TETRACENOMYCIN POLYKETIDE SYNTHESIS O-METHYLTRANSFERASE TCMPDE(270 aa) opt: 368; E(): 1.7e-17;31.3% identity in 233 aa overlap. TBparse score is 0.926 - none - gi|15608293 fig|83332.1.peg.1156 CDS NC_000962 1281482 1280841 -2 - 642 hypothetical protein Rv1154c - none - gi|15608294 fig|83332.1.peg.1157 CDS NC_000962 1281427 1281870 1 + 444 Pyridoxine 5'-phosphate oxidase, Rv1155 - none - gi|15608295 fig|83332.1.peg.1158 CDS NC_000962 1282304 1282891 2 + 588 hypothetical protein Rv1156 - none - gi|15608296 fig|83332.1.peg.1159 CDS NC_000962 1284169 1283054 -1 - 1116 hypothetical protein Rv1157c - none - gi|15608297 fig|83332.1.peg.1160 CDS NC_000962 1284860 1284177 -2 - 684 Conserved alanine and proline rich protein - none - gi|15608298 fig|83332.1.peg.1161 CDS NC_000962 1284990 1286285 3 + 1296 hypothetical protein Rv1159 - none - gi|15608299 fig|83332.1.peg.1162 CDS NC_000962 1286593 1287018 1 + 426 (MTCI65.27), mutT, len: 141. Probable mutator MutT protein or homolog (7,8-dihydro-8-oxoguanine-triphosphatase) (8-OXO-DGTPASE) (EC 3.6.1.-). Is more similar toE. coli MutT homolog (D908197) than to E. coli MutT itself.Contains PS00893 mutT domain signature. FASTA scores: D908197 NID: g1742860 - Escherichia coli (135 aa) opt: 226; E():1.1e-08;39.7% identity in 116 aa overlap. MUTT_ECOLI MUTATORMUTT PROTEIN (129 aa) opt: 180; E(): 1.2e-05; 27.1% identity in129 aa overlap. TBparse score is 0.899 - none - gi|15608300 fig|83332.1.peg.1163 CDS NC_000962 1287326 1291024 2 + 3699 Respiratory nitrate reductase alpha chain (EC 1.7.99.4) Denitrifying reductase gene clusters;
Nitrate and nitrite ammonification gi|15608301 fig|83332.1.peg.1164 CDS NC_000962 1291063 1292739 1 + 1677 Respiratory nitrate reductase beta chain (EC 1.7.99.4) Denitrifying reductase gene clusters;
Nitrate and nitrite ammonification gi|15608302 fig|83332.1.peg.1165 CDS NC_000962 1292796 1293401 3 + 606 Respiratory nitrate reductase delta chain (EC 1.7.99.4) Denitrifying reductase gene clusters;
Nitrate and nitrite ammonification gi|15608303 fig|83332.1.peg.1166 CDS NC_000962 1293404 1294144 2 + 741 Respiratory nitrate reductase gamma chain (EC 1.7.99.4) Denitrifying reductase gene clusters;
Nitrate and nitrite ammonification gi|15608304 fig|83332.1.peg.1167 CDS NC_000962 1294166 1296052 2 + 1887 GTP-binding protein TypA/BipA Universal GTPases gi|15608305 fig|83332.1.peg.1168 CDS NC_000962 1296150 1298057 3 + 1908 (MTV005.02), len: 670. Possible membrane protein, almost identical in part to M. tuberculosis gene fragment TR:G2384665 (EMBL:AF009358) ORFA2-898 (FRAGMENT) (59aa)(93.9% identity in 49 aa overlap) (Nano F.E., Doran J.L.,Treit J.D., Moran A.J.; Identification of Mycobacteriumtuberculosis peptides that stimulate immune human peripheral blood monocytes; Unpublished). Contains possible N-terminalsignal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Alsocontains - none - gi|15608306 fig|83332.1.peg.1169 CDS NC_000962 1298690 1298085 -2 - 606 Transcriptional regulator, TetR family - none - gi|15608307 fig|83332.1.peg.1170 CDS NC_000962 1299802 1298762 -1 - 1041 PPE family protein CBSS-164757.7.peg.5020 gi|15608308 fig|83332.1.peg.1171 CDS NC_000962 1300122 1299820 -3 - 303 (MTV005.05c), len: 100. similar to the N-terminal region of the M. tuberculosis PE family of proteinseg. TR:O05297 (EMBL:Z93777) MTCI364.07 (99 aa), fasta scores; opt: 209 z-score: 407.6 E(): 1.6e-15, 37.4% identityin 99 aa overlap. Also simlar to the N-terminus of M. tuberculosis TR:P77909 (EMBL:U76006) ESTERASE/LIPASE (EC 3.1.1.3) (TRIACYLGLYCEROL LIPASE) (437 aa), fasta scores; opt: 193z-score: 381.8 E(): 4.4e-14, 37.2% identity in 94 aa overlap. Contains a helix-turn-heix motiffrom aa 88-109(+2.76 SD) - none - gi|15608309 fig|83332.1.peg.1172 CDS NC_000962 1300302 1301213 3 + 912 N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB Glutathione analogs: mycothiol;
tRNA aminoacylation, Cys gi|15608310 fig|83332.1.peg.1173 CDS NC_000962 1301383 1301745 1 + 363 hypothetical protein Rv1171 - none - gi|15608311 fig|83332.1.peg.1174 CDS NC_000962 1302679 1301753 -1 - 927 PE-PGRS FAMILY PROTEIN - none - gi|15608312 fig|83332.1.peg.1175 CDS NC_000962 1302929 1305499 2 + 2571 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 1 / 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 2 Coenzyme F420 synthesis;
Coenzyme F420 synthesis gi|15608313 fig|83332.1.peg.1176 CDS NC_000962 1305999 1305667 -3 - 333 hypothetical protein Rv1174c - none - gi|15608314 fig|83332.1.peg.1177 CDS NC_000962 1308224 1306200 -2 - 2025 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34) - none - gi|15608315 fig|83332.1.peg.1178 CDS NC_000962 1308790 1308221 -1 - 570 Transcriptional regulator, PadR family CBSS-1352.1.peg.856 gi|15608316 fig|83332.1.peg.1179 CDS NC_000962 1309003 1309329 1 + 327 4Fe-4S ferredoxin, iron-sulfur binding Inorganic Sulfur Assimilation gi|15608317 fig|83332.1.peg.1180 CDS NC_000962 1309362 1310450 3 + 1089 N-succinyl-L,L-diaminopimelate aminotransferase alternative (EC 2.6.1.17) Lysine Biosynthesis DAP Pathway;
Lysine Biosynthesis DAP Pathway, GJO scratch gi|15608318 fig|83332.1.peg.1181 CDS NC_000962 1313297 1310478 -2 - 2820 DNA or RNA helicases of superfamily II - none - gi|15608319 fig|83332.1.peg.1182 CDS NC_000962 1313723 1315189 2 + 1467 Polyketide synthase - none - gi|15608320 fig|83332.1.peg.1183 CDS NC_000962 1315232 1319980 2 + 4749 (MTV005.17), len: 1582. Probable polyketidesynthase, similar to many eg. MCAS_MYCBO Q02251 mycocerosicacid synthase from mycobacterium bovis (2110 aa), fasta scores; opt: 3518 z-score: 6207.2 E(): 0, 59.7% identity in1614 aaoverlap. Note that this similarity extends upstreamofthefirst initiation codon into the upstream CDS MTV005.16;however the stop codon at the end of MTV005.16 is presentin atleast 4 independent clones (BAC, cosmid and pUC) fromthe genome. The two CDS's may represent separate modulesofthepolyketide synthase. - none - gi|15608321 fig|83332.1.peg.1184 CDS NC_000962 1320033 1321451 3 + 1419 POSSIBLE CONSERVED POLYKETIDE SYNTHASE ASSOCIATED PROTEIN PAPA2 - none - gi|15608322 fig|83332.1.peg.1185 CDS NC_000962 1321518 1324526 3 + 3009 Putative membrane protein - none - gi|15608323 fig|83332.1.peg.1186 CDS NC_000962 1325609 1324530 -2 - 1080 hypothetical protein Rv1184c - none - gi|15608324 fig|83332.1.peg.1187 CDS NC_000962 1327510 1325774 -1 - 1737 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II - none - gi|15608325 fig|83332.1.peg.1188 CDS NC_000962 1329303 1327687 -3 - 1617 hypothetical protein Rv1186c - none - gi|15608326 fig|83332.1.peg.1189 CDS NC_000962 1329388 1331019 1 + 1632 Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.2.1.88) Arginine and Ornithine Degradation;
Proline, 4-hydroxyproline uptake and utilization gi|15608327 fig|83332.1.peg.1190 CDS NC_000962 1331019 1332008 3 + 990 Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase) Proline, 4-hydroxyproline uptake and utilization;
Respiratory dehydrogenases 1 gi|15608328 fig|83332.1.peg.1191 CDS NC_000962 1332090 1332962 3 + 873 (MTV005.25-MTCI364.01), len: 290. Probablesigma factor, similar to eg. TR:O05767 (EMBL:U87307) extracytoplasmic function alternative sigma factor (sigE) fromM. smegmatis (204 aa), fasta scores; opt: 239 z-score: 301.4 E(): 1.3e-09, 32.9% identity in 167 aa overlap. - none - gi|15608329 fig|83332.1.peg.1192 CDS NC_000962 1332978 1333856 3 + 879 hypothetical protein Rv1190 - none - gi|15608330 fig|83332.1.peg.1193 CDS NC_000962 1333929 1334843 3 + 915 putative RNA polymerase sigma factor - none - gi|15608331 fig|83332.1.peg.1194 CDS NC_000962 1334925 1335752 3 + 828 hypothetical protein - none - gi|15608332 fig|83332.1.peg.1195 CDS NC_000962 1335792 1337213 3 + 1422 Long-chain fatty-acid-CoA ligase (EC 6.2.1.3), Mycobacterial subgroup FadD36 - none - gi|15608333 fig|83332.1.peg.1196 CDS NC_000962 1338511 1337246 -1 - 1266 Regulator of polyketide synthase expression - none - gi|15608334 fig|83332.1.peg.1197 CDS NC_000962 1339001 1339300 2 + 300 FIG018298: PE family protein Mycobacterium virulence operon with PE family and Esat6-like proteins;
PPE gene cluster in Mycobacteria gi|15608335 fig|83332.1.peg.1198 CDS NC_000962 1339347 1340522 3 + 1176 FIG013075: PPE family protein CBSS-164757.7.peg.5020;
Mycobacterium virulence operon with PE family and Esat6-like proteins;
PPE gene cluster in Mycobacteria gi|15608336 fig|83332.1.peg.1199 CDS NC_000962 1340657 1340953 2 + 297 ESAT-6-like protein EsxK Mycobacterium virulence operon with Esat6-like proteins;
Mycobacterium virulence operon with PE family and Esat6-like proteins gi|15608337 fig|83332.1.peg.1200 CDS NC_000962 1341004 1341288 1 + 285 ESAT-6-like protein EsxL Mycobacterium virulence operon with Esat6-like proteins;
Mycobacterium virulence operon with PE family and Esat6-like proteins gi|15608338 fig|83332.1.peg.1201 CDS NC_000962 1342603 1341356 -1 - 1248 Mobile element protein - none - gi|15608339 fig|83332.1.peg.1202 CDS NC_000962 1342940 1344217 2 + 1278 Probable conserved integral membrane transport protein - none - gi|15608340 fig|83332.1.peg.1203 CDS NC_000962 1345167 1344214 -3 - 954 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase (EC 2.3.1.117) Lysine Biosynthesis DAP Pathway;
Lysine Biosynthesis DAP Pathway, GJO scratch gi|15608341 fig|83332.1.peg.1204 CDS NC_000962 1345258 1346322 1 + 1065 N-succinyl-L,L-diaminopimelate desuccinylase (EC 3.5.1.18) Arginine Biosynthesis -- gjo;
Arginine Biosynthesis extended;
Lysine Biosynthesis DAP Pathway;
Lysine Biosynthesis DAP Pathway, GJO scratch gi|15608342 fig|83332.1.peg.1205 CDS NC_000962 1346903 1346319 -2 - 585 hypothetical protein - none - gi|15608343 fig|83332.1.peg.1206 CDS NC_000962 1348622 1346934 -2 - 1689 ATPase - none - gi|15608344 fig|83332.1.peg.1207 CDS NC_000962 1348717 1349280 1 + 564 Lysine decarboxylase family - none - gi|15608345 fig|83332.1.peg.1208 CDS NC_000962 1349330 1351123 2 + 1794 (MTCI364.18), len: 597. fadD6, similar to eg mouse fatp Q60714 fatty acid transport protein (646 aa), fasta scores, opt:712, E(): 0, (36.8% identity in 600 aa overlap); contains PS00017 ATP/GTP-binding site motif A (P-loop), PS00455 Putative AMP-binding domain signature - none - gi|15608346 fig|83332.1.peg.1209 CDS NC_000962 1351189 1352145 1 + 957 Non functional Dihydropteroate synthase 2 - none - gi|15608347 fig|83332.1.peg.1210 CDS NC_000962 1352142 1353116 3 + 975 Glycosyltransferases involved in cell wall biogenesis - none - gi|15608348 fig|83332.1.peg.1211 CDS NC_000962 1353155 1353523 2 + 369 hypothetical protein Rv1209 - none - gi|15608349 fig|83332.1.peg.1212 CDS NC_000962 1353520 1354134 1 + 615 DNA-3-methyladenine glycosylase (EC 3.2.2.20) DNA Repair Base Excision gi|15608350 fig|83332.1.peg.1213 CDS NC_000962 1354241 1354468 2 + 228 hypothetical protein Rv1211 - none - gi|15608351 fig|83332.1.peg.1214 CDS NC_000962 1355659 1354496 -1 - 1164 Predicted glycogen synthase, ADP-glucose transglucosylase (EC 2.4.1.21), Actinobacterial type Glycogen metabolism gi|15608352 fig|83332.1.peg.1215 CDS NC_000962 1355834 1357048 2 + 1215 Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27) Glycogen metabolism gi|15608353 fig|83332.1.peg.1216 CDS NC_000962 1357623 1357291 -3 - 333 PE-PGRS FAMILY PROTEIN - none - gi|15608354 fig|83332.1.peg.1217 CDS NC_000962 1359442 1357757 -1 - 1686 hypothetical protein Rv1215c - none - gi|15608355 fig|83332.1.peg.1218 CDS NC_000962 1360144 1359470 -1 - 675 hypothetical protein Rv1216c - none - gi|15608356 fig|83332.1.peg.1219 CDS NC_000962 1361799 1360153 -3 - 1647 hypothetical protein Rv1217c - none - gi|15608357 fig|83332.1.peg.1220 CDS NC_000962 1362731 1361796 -2 - 936 hypothetical protein Rv1218c - none - gi|15608358 fig|83332.1.peg.1221 CDS NC_000962 1363359 1362721 -3 - 639 Transcriptional regulator, TetR family - none - gi|15608359 fig|83332.1.peg.1222 CDS NC_000962 1364148 1363501 -3 - 648 hypothetical protein Rv1220c - none - gi|15608360 fig|83332.1.peg.1223 CDS NC_000962 1364411 1365184 2 + 774 (MTCI61.04), sigE, len: 257. Alternative sigma factor of extracytoplasmic function (ECF) family, see Wu Q.L.,Kong D., Lam K., Husson R.N.; A Mycobacterial extracytoplasmic function sigma factor involved in survival following stress; J. Bacteriol. 179:2922-2929(1997). Similar tomany eg. RPOE_HAEIN P44790 rna polymerase sigma-e factor (189 aa),opt: 247 z-score: 235.9 E(): 3.4e-06, 28.5% identityin 186aa overlap. Also similar to M. tuberculosis rpoE (MTCY07D11.03) (35.2% identity in 159 aa overlap) - none - gi|15608361 fig|83332.1.peg.1224 CDS NC_000962 1365342 1365806 3 + 465 hypothetical protein Rv1222 - none - gi|15608362 fig|83332.1.peg.1225 CDS NC_000962 1365810 1367459 3 + 1650 (MTCI61.06), htrA, len: 549. DegP protease serine protease homolog, similar to many eg. HTRA_ECOLI P09376 protease do precursor (ec 3.4.21.-) (474 aa), fasta scores; opt:581 z-score: 605.2 E(): 9.1e-27, 36.3% identity in278 aa overlap. Identical to PID:g2062626 from EMBL:MTU87242. Contains PS00017 ATP/GTP-binding site motif A (P-loop) - none - gi|15608363 fig|83332.1.peg.1226 CDS NC_000962 1367461 1367856 1 + 396 Twin-arginine translocation protein TatB Twin-arginine translocation system gi|15608364 fig|83332.1.peg.1227 CDS NC_000962 1368719 1367889 -2 - 831 HAD-superfamily subfamily IIA hydrolase, hypothetical 2 - none - gi|15608365 fig|83332.1.peg.1228 CDS NC_000962 1370293 1368830 -1 - 1464 transmembrane protein, distant homology with ydbT - none - gi|15608366 fig|83332.1.peg.1229 CDS NC_000962 1370823 1370290 -3 - 534 transmembrane protein, distant homology with ydbS Folate biosynthesis cluster gi|15608367 fig|83332.1.peg.1230 CDS NC_000962 1370918 1371475 2 + 558 (MTCI61.11), len: 185. Unknown, contains possible signal sequence and appropriately positioned PS00013Prokaryotic membrane lipoprotein lipid attachment site - none - gi|15608368 fig|83332.1.peg.1231 CDS NC_000962 1372947 1371775 -3 - 1173 (MTCI61.12c-MTV006.01c), len: 390. Memberof MRP/NBP35 FAMILY OF ATP-BINDING proteins of unknown function, similar to eg. MRP_ECOLI P21590 mrp protein. escherichiacoli (379 aa), fasta results; E(): 0, 34.1% identity in355 aa overlap. Contains PS00017 ATP/GTP-binding site motif A(P-loop). - none - gi|15608369 fig|83332.1.peg.1232 CDS NC_000962 1374195 1372960 -3 - 1236 hypothetical protein Rv1230c - none - gi|15608370 fig|83332.1.peg.1233 CDS NC_000962 1374862 1374320 -1 - 543 hypothetical protein Rv1231c - none - gi|15608371 fig|83332.1.peg.1234 CDS NC_000962 1376166 1374859 -3 - 1308 Mg/Co/Ni transporter MgtE / CBS domain Magnesium transport;
Purine salvage cluster gi|15608372 fig|83332.1.peg.1235 CDS NC_000962 1376824 1376228 -1 - 597 hypothetical protein Rv1233c - none - gi|15608373 fig|83332.1.peg.1236 CDS NC_000962 1376974 1377501 1 + 528 hypothetical protein Rv1234 - none - gi|15608374 fig|83332.1.peg.1237 CDS NC_000962 1377522 1378928 3 + 1407 Maltose/maltodextrin ABC transporter, substrate binding periplasmic protein MalE - none - gi|15608375 fig|83332.1.peg.1238 CDS NC_000962 1378925 1379848 2 + 924 Maltose/maltodextrin ABC transporter, permease protein MalF - none - gi|15608376 fig|83332.1.peg.1239 CDS NC_000962 1379853 1380677 3 + 825 Maltose/maltodextrin ABC transporter, permease protein MalG - none - gi|15608377 fig|83332.1.peg.1240 CDS NC_000962 1380682 1381863 1 + 1182 Maltose/maltodextrin transport ATP-binding protein MalK (EC 3.6.3.19) Glycerol and Glycerol-3-phosphate Uptake and Utilization gi|15608378 fig|83332.1.peg.1241 CDS NC_000962 1383040 1381940 -1 - 1101 Magnesium and cobalt transport protein CorA Magnesium transport gi|15608379 fig|83332.1.peg.1242 CDS NC_000962 1383211 1384200 1 + 990 Malate dehydrogenase (EC 1.1.1.37) Glyoxylate bypass;
Serine-glyoxylate cycle;
TCA Cycle gi|15608380 fig|83332.1.peg.1243 CDS NC_000962 1384276 1384536 1 + 261 hypothetical protein Rv1241 - none - gi|15608381 fig|83332.1.peg.1244 CDS NC_000962 1384533 1384964 3 + 432 Toxin 1, PIN domain Toxin-Antitoxin MT1 gi|15608382 fig|83332.1.peg.1245 CDS NC_000962 1386675 1384987 -3 - 1689 (MTV006.15c), len: 562. Unknown, member ofPE family of glycine-rich M. tuberculosis proteins, PGRS subfamily. TBparse score is 0.875 - none - gi|15608383 fig|83332.1.peg.1246 CDS NC_000962 1386855 1387715 3 + 861 (MTV006.16), len: 286. Unknown lipoproteinequivalentto M. leprae protein u1756x (228 aa). FASTA scores: U15180|MLU1518042 opt: 1039 E(): 0; (72.5% identity in 229 aa overlap). Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site. TBparse score is 0.878 - none - gi|15608384 fig|83332.1.peg.1247 CDS NC_000962 1388626 1387796 -1 - 831 hypothetical protein Rv1245c - none - gi|15608385 fig|83332.1.peg.1248 CDS NC_000962 1388976 1388683 -3 - 294 RelE/StbE replicon stabilization toxin Toxin-antitoxin replicon stabilization systems gi|15608386 fig|83332.1.peg.1249 CDS NC_000962 1389242 1388973 -2 - 270 RelB/StbD replicon stabilization protein (antitoxin to RelE/StbE) Toxin-antitoxin replicon stabilization systems gi|15608387 fig|83332.1.peg.1250 CDS NC_000962 1392999 1389355 -3 - 3645 Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) / 2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2) Dehydrogenase complexes;
Dehydrogenase complexes;
Lipoic acid metabolism;
TCA Cycle;
TCA Cycle gi|15608388 fig|83332.1.peg.1251 CDS NC_000962 1393980 1393192 -3 - 789 hypothetical protein Rv1249c - none - gi|15608389 fig|83332.1.peg.1252 CDS NC_000962 1394177 1395916 2 + 1740 hypothetical protein Rv1250 - none - gi|15608390 fig|83332.1.peg.1253 CDS NC_000962 1399238 1395819 -2 - 3420 hypothetical protein Rv1251c - none - gi|15608391 fig|83332.1.peg.1254 CDS NC_000962 1399902 1399294 -3 - 609 Putative lipoprotein lprE precursor - none - gi|15608392 fig|83332.1.peg.1255 CDS NC_000962 1399968 1401659 3 + 1692 Cold-shock DEAD-box protein A ATP-dependent RNA helicases, bacterial gi|15608393 fig|83332.1.peg.1256 CDS NC_000962 1401656 1402807 2 + 1152 hypothetical protein Rv1254 - none - gi|15608394 fig|83332.1.peg.1257 CDS NC_000962 1403384 1402776 -2 - 609 Transcriptional regulator, TetR family - none - gi|15608395 fig|83332.1.peg.1258 CDS NC_000962 1404601 1403384 -1 - 1218 Cytochrome P450 130 - none - gi|15608396 fig|83332.1.peg.1259 CDS NC_000962 1406082 1404715 -3 - 1368 Glycolate dehydrogenase (EC 1.1.99.14), subunit GlcD - none - gi|15608397 fig|83332.1.peg.1260 CDS NC_000962 1407338 1406079 -2 - 1260 hypothetical protein Rv1258c - none - gi|15608398 fig|83332.1.peg.1261 CDS NC_000962 1407337 1408236 1 + 900 Uracil-DNA glycosylase, family 5 Uracil-DNA glycosylase gi|15608399 fig|83332.1.peg.1262 CDS NC_000962 1408238 1409356 2 + 1119 hypothetical protein Rv1260 - none - gi|15608400 fig|83332.1.peg.1263 CDS NC_000962 1409931 1409482 -3 - 450 hypothetical protein Rv1261c - none - gi|15608401 fig|83332.1.peg.1264 CDS NC_000962 1410370 1409936 -1 - 435 Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) (EC 3.6.1.17) pyrimidine conversions gi|15608402 fig|83332.1.peg.1265 CDS NC_000962 1410429 1411817 3 + 1389 (MTCY50.19c), len: 462. amiB2, Probable amidase, similar to G1001278 hypothetical 54.3 kDa protein (506aa) opt: 767, z-score: 839.9, E(): 7.6e-40, (32.8% identity in 461 aa overlap), also to G580673 rhodococcus enantioselective amidase gene (462aa) FASTA scores, opt: 668, z-score: 732.5, E(): 7.4e-34, (33.5% identity in 484 aa overlap) also to e.g. NYLA_PSES8 P13398 6-aminohexanoate-cyclic-dimer hydrolase (492 aa) opt: 543, z-score: 595.7, E(): 3.1e-26, (33.5% identity in 493 aaoverlap); contains PS00017 ATP/GTP-binding site motif A; also similar to MTCY274.19c (33.5%identity in 427 aa overlap) - none - gi|15608403 fig|83332.1.peg.1266 CDS NC_000962 1411892 1413085 2 + 1194 Adenylate cyclase (EC 4.6.1.1) cAMP signaling in bacteria gi|15608404 fig|83332.1.peg.1267 CDS NC_000962 1413258 1413938 3 + 681 hypothetical protein Rv1265 - none - gi|15608405 fig|83332.1.peg.1268 CDS NC_000962 1415838 1413958 -3 - 1881 (MTCY50.16), len: 626. Probable serine/threonine-protein kinase, similar to eg PKN1_MYXXA P33973 pkn1(693 aa) FASTA scores, opt: 611, z-score: 386.3, E(): 1.4e-14, (29.7% identityin 492 aa overlap), contains PS00107 Protein kinases ATP-binding region signature; PS00108 Serine/Threonine protein kinases active-site signature - none - gi|15608406 fig|83332.1.peg.1269 CDS NC_000962 1417345 1416179 -1 - 1167 transcriptional regulator, AfsR/DnrI/RedD family - none - gi|15608407 fig|83332.1.peg.1270 CDS NC_000962 1418354 1417656 -2 - 699 hypothetical protein Rv1268c - none - gi|15608408 fig|83332.1.peg.1271 CDS NC_000962 1418951 1418577 -2 - 375 hypothetical protein Rv1269c - none - gi|15608409 fig|83332.1.peg.1272 CDS NC_000962 1419746 1419012 -2 - 735 Lipoprotein LprG precursor - none - gi|15608410 fig|83332.1.peg.1273 CDS NC_000962 1420300 1419959 -1 - 342 hypothetical protein Rv1271c - none - gi|15608411 fig|83332.1.peg.1274 CDS NC_000962 1422303 1420408 -3 - 1896 Uncharacterized ABC transporter ATP-binding protein Rv1272c/MT1310 - none - gi|15608412 fig|83332.1.peg.1275 CDS NC_000962 1424048 1422300 -2 - 1749 Uncharacterized ABC transporter ATP-binding protein Rv1273c/MT1311 - none - gi|15608413 fig|83332.1.peg.1276 CDS NC_000962 1424195 1424752 2 + 558 Putative lipoprotein LprB precursor - none - gi|15608414 fig|83332.1.peg.1277 CDS NC_000962 1424749 1425291 1 + 543 Putative lipoprotein LprC precursor - none - gi|15608415 fig|83332.1.peg.1278 CDS NC_000962 1425912 1425436 -3 - 477 Phosphohistidine phosphatase SixA - none - gi|15608416 fig|83332.1.peg.1279 CDS NC_000962 1426162 1427415 1 + 1254 DNA double-strand break repair protein Mre11 Rad50-Mre11 DNA repair cluster gi|15608417 fig|83332.1.peg.1280 CDS NC_000962 1427412 1430039 3 + 2628 DNA double-strand break repair Rad50 ATPase Rad50-Mre11 DNA repair cluster gi|15608418 fig|83332.1.peg.1281 CDS NC_000962 1430060 1431646 2 + 1587 Choline dehydrogenase (EC 1.1.99.1) Choline and Betaine Uptake and Betaine Biosynthesis gi|15608419 fig|83332.1.peg.1282 CDS NC_000962 1433438 1431663 -2 - 1776 Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1) ABC transporter oligopeptide (TC 3.A.1.5.1) gi|15608420 fig|83332.1.peg.1283 CDS NC_000962 1435269 1433431 -3 - 1839 Oligopeptide transport system permease protein OppB (TC 3.A.1.5.1) ABC transporter oligopeptide (TC 3.A.1.5.1) gi|15608421 fig|83332.1.peg.1284 CDS NC_000962 1436141 1435266 -2 - 876 Oligopeptide transport system permease protein OppC (TC 3.A.1.5.1) ABC transporter oligopeptide (TC 3.A.1.5.1) gi|15608422 fig|83332.1.peg.1285 CDS NC_000962 1437115 1436138 -1 - 978 Oligopeptide transport system permease protein OppB (TC 3.A.1.5.1) ABC transporter oligopeptide (TC 3.A.1.5.1) gi|15608423 fig|83332.1.peg.1286 CDS NC_000962 1437322 1437813 1 + 492 Carbonic anhydrase (EC 4.2.1.1) - none - gi|15608424 fig|83332.1.peg.1287 CDS NC_000962 1437907 1438905 1 + 999 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) Cysteine Biosynthesis;
Inorganic Sulfur Assimilation gi|15608425 fig|83332.1.peg.1288 CDS NC_000962 1438905 1440749 3 + 1845 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) Cysteine Biosynthesis;
Cysteine Biosynthesis;
Inorganic Sulfur Assimilation;
Inorganic Sulfur Assimilation gi|15608426 fig|83332.1.peg.1289 CDS NC_000962 1440803 1441288 2 + 486 Predicted transcriptional regulator of sulfate adenylyltransferase, Rrf2 family Rrf2 family transcriptional regulators gi|15608427 fig|83332.1.peg.1290 CDS NC_000962 1441346 1442716 2 + 1371 hypothetical protein Rv1288 - none - gi|15608428 fig|83332.1.peg.1291 CDS NC_000962 1442765 1443397 2 + 633 hypothetical protein Rv1289 - none - gi|15608429 fig|83332.1.peg.1292 CDS NC_000962 1445045 1443480 -2 - 1566 hypothetical protein Rv1290c - none - gi|15608430 fig|83332.1.peg.1293 CDS NC_000962 1445832 1445497 -3 - 336 FIG00823516: hypothetical protein - none - gi|15608431 fig|83332.1.peg.1294 CDS NC_000962 1446377 1448029 2 + 1653 Arginyl-tRNA synthetase (EC 6.1.1.19) tRNA aminoacylation, Arg gi|15608432 fig|83332.1.peg.1295 CDS NC_000962 1448026 1449369 1 + 1344 Diaminopimelate decarboxylase (EC 4.1.1.20) Lysine Biosynthesis DAP Pathway;
Lysine Biosynthesis DAP Pathway, GJO scratch gi|15608433 fig|83332.1.peg.1296 CDS NC_000962 1449373 1450698 1 + 1326 Homoserine dehydrogenase (EC 1.1.1.3) Methionine Biosynthesis;
Threonine and Homoserine Biosynthesis gi|15608434 fig|83332.1.peg.1297 CDS NC_000962 1450695 1451777 3 + 1083 Threonine synthase (EC 4.2.3.1) Threonine and Homoserine Biosynthesis gi|15608435 fig|83332.1.peg.1298 CDS NC_000962 1451995 1452945 1 + 951 Homoserine kinase (EC 2.7.1.39) Methionine Biosynthesis;
Threonine and Homoserine Biosynthesis gi|15608436 fig|83332.1.peg.1299 CDS NC_000962 1453202 1455010 2 + 1809 Transcription termination factor Rho Transcription factors bacterial gi|15608437 fig|83332.1.peg.1300 CDS NC_000962 1455161 1455403 2 + 243 LSU ribosomal protein L31p @ LSU ribosomal protein L31p, zinc-dependent Ribosome LSU bacterial;
Ribosome LSU bacterial gi|15608438 fig|83332.1.peg.1301 CDS NC_000962 1455493 1456566 1 + 1074 Peptide chain release factor 1 Glutaredoxins;
Translation termination factors bacterial;
YrdC-YciO-Sua5 protein family gi|15608439 fig|83332.1.peg.1302 CDS NC_000962 1456563 1457540 3 + 978 Protein-N(5)-glutamine methyltransferase PrmC, methylates polypeptide chain release factors RF1 and RF2 RNA methylation;
Translation termination factors bacterial;
YrdC-YciO-Sua5 protein family gi|15608440 fig|83332.1.peg.1303 CDS NC_000962 1457556 1458209 3 + 654 TsaC protein (YrdC domain) required for threonylcarbamoyladenosine t(6)A37 modification in tRNA YrdC-YciO-Sua5 protein family gi|15608441 fig|83332.1.peg.1304 CDS NC_000962 1458293 1459507 2 + 1215 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) - none - gi|15608442 fig|83332.1.peg.1305 CDS NC_000962 1459764 1460249 3 + 486 FIG048548: ATP synthase protein I2 F0F1-type ATP synthase gi|15608443 fig|83332.1.peg.1306 CDS NC_000962 1460242 1460994 1 + 753 ATP synthase F0 sector subunit a (EC 3.6.3.14) F0F1-type ATP synthase gi|15608444 fig|83332.1.peg.1307 CDS NC_000962 1461043 1461288 1 + 246 ATP synthase F0 sector subunit c (EC 3.6.3.14) F0F1-type ATP synthase gi|15608445 fig|83332.1.peg.1308 CDS NC_000962 1461319 1461834 1 + 516 ATP synthase F0 sector subunit b' (EC 3.6.3.14) F0F1-type ATP synthase gi|15608446 fig|83332.1.peg.1309 CDS NC_000962 1461841 1463181 1 + 1341 ATP synthase F0 sector subunit b (EC 3.6.3.14) / ATP synthase delta chain (EC 3.6.3.14) F0F1-type ATP synthase;
F0F1-type ATP synthase gi|15608447 fig|83332.1.peg.1310 CDS NC_000962 1463226 1464875 3 + 1650 ATP synthase alpha chain (EC 3.6.3.14) F0F1-type ATP synthase gi|15608448 fig|83332.1.peg.1311 CDS NC_000962 1464882 1465799 3 + 918 ATP synthase gamma chain (EC 3.6.3.14) F0F1-type ATP synthase gi|15608449 fig|83332.1.peg.1312 CDS NC_000962 1465839 1467299 3 + 1461 ATP synthase beta chain (EC 3.6.3.14) F0F1-type ATP synthase gi|15608450 fig|83332.1.peg.1313 CDS NC_000962 1467313 1467678 1 + 366 ATP synthase epsilon chain (EC 3.6.3.14) F0F1-type ATP synthase gi|15608451 fig|83332.1.peg.1314 CDS NC_000962 1467686 1468129 2 + 444 possible secreted protein - none - gi|15608452 fig|83332.1.peg.1315 CDS NC_000962 1469503 1468169 -1 - 1335 Mobile element protein - none - gi|15608453 fig|83332.1.peg.1316 CDS NC_000962 1470250 1469669 -1 - 582 ATP:Cob(I)alamin adenosyltransferase (EC 2.5.1.17) G3E family of P-loop GTPases (metallocenter biosynthesis) gi|15608454 fig|83332.1.peg.1317 CDS NC_000962 1470319 1471575 1 + 1257 UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7) Peptidoglycan Biosynthesis;
UDP-N-acetylmuramate from Fructose-6-phosphate Biosynthesis gi|15608455 fig|83332.1.peg.1318 CDS NC_000962 1477629 1477132 -3 - 498 Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) DNA repair, bacterial gi|15608456 fig|83332.1.peg.1319 CDS NC_000962 1479116 1477626 -2 - 1491 Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) DNA repair, bacterial gi|15608457 fig|83332.1.peg.1320 CDS NC_000962 1480822 1479197 -1 - 1626 Adenylate cyclase (EC 4.6.1.1) cAMP signaling in bacteria gi|15608458 fig|83332.1.peg.1321 CDS NC_000962 1482499 1480892 -1 - 1608 Adenylate cyclase (EC 4.6.1.1) cAMP signaling in bacteria gi|15608459 fig|83332.1.peg.1322 CDS NC_000962 1484215 1482512 -1 - 1704 Adenylate cyclase (EC 4.6.1.1) cAMP signaling in bacteria gi|15608460 fig|83332.1.peg.1323 CDS NC_000962 1484277 1484957 3 + 681 Protein of unknown function DUF91 - none - gi|15608461 fig|83332.1.peg.1324 CDS NC_000962 1484980 1485276 1 + 297 Putative ATP/GTP-binding protein, doubtful CDS - none - gi|15608462 fig|83332.1.peg.1325 CDS NC_000962 1485860 1487029 2 + 1170 3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9) Acetyl-CoA fermentation to Butyrate;
Biotin biosynthesis;
Biotin synthesis cluster;
Butanol Biosynthesis;
CBSS-246196.1.peg.364;
Fatty acid metabolism cluster;
Isoleucine degradation;
Isoprenoid Biosynthesis;
Polyhydroxybutyrate metabolism;
Polyhydroxybutyrate metabolism;
Serine-glyoxylate cycle;
Serine-glyoxylate cycle gi|15608463 fig|83332.1.peg.1326 CDS NC_000962 1487159 1488073 2 + 915 FIG000875: Thioredoxin domain-containing protein EC-YbbN - none - gi|15608464 fig|83332.1.peg.1327 CDS NC_000962 1489963 1488152 -1 - 1812 PE-PGRS FAMILY PROTEIN - none - gi|15608465 fig|83332.1.peg.1328 CDS NC_000962 1492310 1490115 -2 - 2196 1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type (EC 2.4.1.18) Glycogen metabolism;
Trehalose Biosynthesis gi|15608466 fig|83332.1.peg.1329 CDS NC_000962 1494531 1492318 -3 - 2214 Putative glucanase glgE (EC 3.2.1.-) Trehalose Biosynthesis gi|15608467 fig|83332.1.peg.1330 CDS NC_000962 1494562 1497153 1 + 2592 Glycogen phosphorylase (EC 2.4.1.1) Glycogen metabolism;
Maltose and Maltodextrin Utilization gi|15608468 fig|83332.1.peg.1331 CDS NC_000962 1499187 1497193 -3 - 1995 DinG family ATP-dependent helicase YoaA DNA repair, bacterial DinG and relatives gi|15608469 fig|83332.1.peg.1332 CDS NC_000962 1500740 1499211 -2 - 1530 Nicotinate phosphoribosyltransferase (EC 2.4.2.11) NAD and NADP cofactor biosynthesis global;
Redox-dependent regulation of nucleus processes gi|15608470 fig|83332.1.peg.1333 CDS NC_000962 1500659 1500964 2 + 306 ATP-dependent Clp protease adaptor protein ClpS Proteolysis in bacteria, ATP-dependent gi|15608471 fig|83332.1.peg.1334 CDS NC_000962 1500924 1501580 3 + 657 DUF2017 domain-containing protein - none - gi|15608472 fig|83332.1.peg.1335 CDS NC_000962 1501597 1502631 1 + 1035 possible hydrolase - none - gi|15608473 fig|83332.1.peg.1336 CDS NC_000962 1502639 1503079 2 + 441 hypothetical protein Rv1334 - none - gi|15608474 fig|83332.1.peg.1337 CDS NC_000962 1503101 1503382 2 + 282 FIG038648: MoaD and/or ThiS families - none - gi|15608475 fig|83332.1.peg.1338 CDS NC_000962 1503392 1504363 2 + 972 Cysteine synthase B (EC 2.5.1.47) Cysteine Biosynthesis gi|15608476 fig|83332.1.peg.1339 CDS NC_000962 1504354 1505076 1 + 723 Rhomboid family protein - none - gi|15608477 fig|83332.1.peg.1340 CDS NC_000962 1505073 1505888 3 + 816 Glutamate racemase (EC 5.1.1.3) Glutamine, Glutamate, Aspartate and Asparagine Biosynthesis;
Peptidoglycan Biosynthesis gi|15608478 fig|83332.1.peg.1341 CDS NC_000962 1505915 1506736 2 + 822 hypothetical protein Rv1339 - none - gi|15608479 fig|83332.1.peg.1342 CDS NC_000962 1506753 1507532 3 + 780 Ribonuclease PH (EC 2.7.7.56) Heat shock dnaK gene cluster extended;
tRNA processing gi|15608480 fig|83332.1.peg.1343 CDS NC_000962 1507571 1508185 2 + 615 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) Heat shock dnaK gene cluster extended;
Heme and Siroheme Biosynthesis;
Housecleaning nucleoside triphosphate pyrophosphatases gi|15608481 fig|83332.1.peg.1344 CDS NC_000962 1508544 1508182 -3 - 363 CONSERVED MEMBRANE PROTEIN - none - gi|15608482 fig|83332.1.peg.1345 CDS NC_000962 1508921 1508541 -2 - 381 hypothetical protein Rv1343c - none - gi|15608483 fig|83332.1.peg.1346 CDS NC_000962 1508966 1509286 2 + 321 hypothetical protein Rv1344 - none - gi|15608484 fig|83332.1.peg.1347 CDS NC_000962 1509279 1510844 3 + 1566 acyl-CoA synthetase - none - gi|15608485 fig|83332.1.peg.1348 CDS NC_000962 1510844 1512004 2 + 1161 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) - none - gi|15608486 fig|83332.1.peg.1349 CDS NC_000962 1512603 1511971 -3 - 633 Lysine N-acyltransferase mbtK (EC 2.3.1.-) (N-acyltransferase mbtK) (Mycobactin synthetase protein K) - none - gi|15608487 fig|83332.1.peg.1350 CDS NC_000962 1513045 1515624 1 + 2580 hypothetical protein Rv1348 - none - gi|15608488 fig|83332.1.peg.1351 CDS NC_000962 1515621 1517360 3 + 1740 hypothetical protein Rv1349 - none - gi|15608489 fig|83332.1.peg.1352 CDS NC_000962 1517489 1518232 2 + 744 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) - none - gi|15608490 fig|83332.1.peg.1353 CDS NC_000962 1518229 1518558 1 + 330 hypothetical protein - none - gi|15608491 fig|83332.1.peg.1354 CDS NC_000962 1518761 1519132 2 + 372 hypothetical protein - none - gi|15608492 fig|83332.1.peg.1355 CDS NC_000962 1519983 1519198 -3 - 786 Transcriptional regulator, TetR family - none - gi|15608493 fig|83332.1.peg.1356 CDS NC_000962 1521874 1520003 -1 - 1872 hypothetical protein Rv1354c - none - gi|15608494 fig|83332.1.peg.1357 CDS NC_000962 1524030 1521883 -3 - 2148 POSSIBLE MOLYBDOPTERIN BIOSYNTHESIS PROTEIN MOEY - none - gi|15608495 fig|83332.1.peg.1358 CDS NC_000962 1524818 1524027 -2 - 792 hypothetical protein Rv1356c - none - gi|15608496 fig|83332.1.peg.1359 CDS NC_000962 1526214 1525291 -3 - 924 hypothetical protein Rv1357c - none - gi|15608497 fig|83332.1.peg.1360 CDS NC_000962 1526610 1530089 3 + 3480 Adenylyl cyclase class-3/4/guanylyl cyclase / Transcriptional regulator, LuxR family - none - gi|15608498 fig|83332.1.peg.1361 CDS NC_000962 1530171 1530923 3 + 753 Adenylyl cyclase class-3/4/guanylyl cyclase - none - gi|15608499 fig|83332.1.peg.1362 CDS NC_000962 1531346 1532368 2 + 1023 hypothetical protein Rv1360 - none - gi|15608500 fig|83332.1.peg.1363 CDS NC_000962 1533631 1532441 -1 - 1191 (MTCY02B10.25c), len: 396. Member of the PPE family of proteins, similar to e.g. MTCI364.08, fasta scores; E(): 0, 84.9% identity in 397 aa overlap; contains PS00501 Signal peptidases I serine active site; also similarto MTCY274.23c (42.3% identity in 416aa overlap) - none - gi|15608501 fig|83332.1.peg.1364 CDS NC_000962 1534608 1533946 -3 - 663 hypothetical protein Rv1362c - none - gi|15608502 fig|83332.1.peg.1365 CDS NC_000962 1535390 1534605 -2 - 786 hypothetical protein Rv1363c - none - gi|15608503 fig|83332.1.peg.1366 CDS NC_000962 1537642 1535681 -1 - 1962 Serine phosphatase RsbU, regulator of sigma subunit - none - gi|15608504 fig|83332.1.peg.1367 CDS NC_000962 1538167 1537781 -1 - 387 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV - none - gi|15608505 fig|83332.1.peg.1368 CDS NC_000962 1538388 1539209 3 + 822 GTP pyrophosphokinase (EC 2.7.6.5) - none - gi|15608506 fig|83332.1.peg.1369 CDS NC_000962 1540643 1539510 -2 - 1134 Beta-lactamase class C and other penicillin binding proteins Beta-lactamase gi|15608507 fig|83332.1.peg.1370 CDS NC_000962 1541018 1541803 2 + 786 putative lipoprotein lprF precursor - none - gi|15608508 fig|83332.1.peg.1371 CDS NC_000962 1542876 1541992 -3 - 885 Mobile element protein - none - gi|15608509 fig|83332.1.peg.1372 CDS NC_000962 1543253 1542927 -2 - 327 Mobile element protein - none - gi|15608510 fig|83332.1.peg.1373 CDS NC_000962 1543357 1544826 1 + 1470 hypothetical protein Rv1371 - none - gi|15608511 fig|83332.1.peg.1374 CDS NC_000962 1544823 1546004 3 + 1182 Chalcone synthase (EC 2.3.1.74) - none - gi|15608512 fig|83332.1.peg.1375 CDS NC_000962 1546010 1546990 2 + 981 Glycolipid sulfotransferase - none - gi|15608513 fig|83332.1.peg.1376 CDS NC_000962 1547531 1547070 -2 - 462 hypothetical protein Rv1374c - none - gi|15608514 fig|83332.1.peg.1377 CDS NC_000962 1547830 1549149 1 + 1320 hypothetical protein Rv1375 - none - gi|15608515 fig|83332.1.peg.1378 CDS NC_000962 1549146 1550639 3 + 1494 hypothetical protein Rv1376 - none - gi|15608516 fig|83332.1.peg.1379 CDS NC_000962 1551215 1550577 -2 - 639 Methyltransferase (EC 2.1.1.-) - none - gi|15608517 fig|83332.1.peg.1380 CDS NC_000962 1552653 1551226 -3 - 1428 hypothetical protein Rv1378c - none - gi|15608518 fig|83332.1.peg.1381 CDS NC_000962 1552652 1553233 2 + 582 Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR De Novo Pyrimidine Synthesis;
De Novo Pyrimidine Synthesis;
pyrimidine conversions gi|15608519 fig|83332.1.peg.1382 CDS NC_000962 1553230 1554189 1 + 960 Aspartate carbamoyltransferase (EC 2.1.3.2) De Novo Pyrimidine Synthesis gi|15608520 fig|83332.1.peg.1383 CDS NC_000962 1554186 1555478 3 + 1293 Dihydroorotase (EC 3.5.2.3) De Novo Pyrimidine Synthesis gi|15608521 fig|83332.1.peg.1384 CDS NC_000962 1555475 1555972 2 + 498 FIG024784: Integral membrane protein related to pyrimidine synthesis De Novo Pyrimidine Synthesis gi|15608522 fig|83332.1.peg.1385 CDS NC_000962 1555969 1557099 1 + 1131 Carbamoyl-phosphate synthase small chain (EC 6.3.5.5) De Novo Pyrimidine Synthesis;
Macromolecular synthesis operon gi|15608523 fig|83332.1.peg.1386 CDS NC_000962 1557099 1560446 3 + 3348 Carbamoyl-phosphate synthase large chain (EC 6.3.5.5) De Novo Pyrimidine Synthesis;
Macromolecular synthesis operon gi|15611062 fig|83332.1.peg.1387 CDS NC_000962 1560443 1561267 2 + 825 Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) De Novo Pyrimidine Synthesis;
Riboflavin synthesis cluster gi|15608524 fig|83332.1.peg.1388 CDS NC_000962 1561462 1561770 1 + 309 PE family protein - none - gi|15608525 fig|83332.1.peg.1389 CDS NC_000962 1561767 1563386 3 + 1620 PPE family protein - none - gi|15608526 fig|83332.1.peg.1390 CDS NC_000962 1563692 1564264 2 + 573 integration host factor - none - gi|15608527 fig|83332.1.peg.1391 CDS NC_000962 1564399 1565025 1 + 627 Guanylate kinase (EC 2.7.4.8) Purine conversions gi|15608528 fig|83332.1.peg.1392 CDS NC_000962 1565091 1565423 3 + 333 DNA-directed RNA polymerase omega subunit (EC 2.7.7.6) CBSS-176299.4.peg.1292;
RNA polymerase bacterial gi|15608529 fig|83332.1.peg.1393 CDS NC_000962 1565439 1566695 3 + 1257 Phosphopantothenoylcysteine decarboxylase (EC 4.1.1.36) / Phosphopantothenoylcysteine synthetase (EC 6.3.2.5) Coenzyme A Biosynthesis;
Coenzyme A Biosynthesis gi|15608530 fig|83332.1.peg.1394 CDS NC_000962 1566823 1568034 1 + 1212 S-adenosylmethionine synthetase (EC 2.5.1.6) Methionine Biosynthesis;
Methionine Degradation gi|15608531 fig|83332.1.peg.1395 CDS NC_000962 1569585 1568107 -3 - 1479 hypothetical protein Rv1393c - none - gi|15608532 fig|83332.1.peg.1396 CDS NC_000962 1570967 1569582 -2 - 1386 Cytochrome P450 132 - none - gi|15608533 fig|83332.1.peg.1397 CDS NC_000962 1571045 1572079 2 + 1035 Transcriptional regulator, AraC family - none - gi|15611063 fig|83332.1.peg.1398 CDS NC_000962 1573855 1572125 -1 - 1731 PE family protein - none - gi|15608534 fig|83332.1.peg.1399 CDS NC_000962 1574511 1574110 -3 - 402 hypothetical protein Rv1397c - none - gi|15608535 fig|83332.1.peg.1400 CDS NC_000962 1574765 1574508 -2 - 258 hypothetical protein Rv1398c - none - gi|15608536 fig|83332.1.peg.1401 CDS NC_000962 1575807 1574848 -3 - 960 Esterase/lipase - none - gi|15608537 fig|83332.1.peg.1402 CDS NC_000962 1576794 1575832 -3 - 963 Esterase/lipase - none - gi|15608538 fig|83332.1.peg.1403 CDS NC_000962 1576928 1577530 2 + 603 hypothetical protein Rv1401 - none - gi|15608539 fig|83332.1.peg.1404 CDS NC_000962 1577611 1579578 1 + 1968 Helicase PriA essential for oriC/DnaA-independent DNA replication Conserved gene cluster associated with Met-tRNA formyltransferase gi|15608540 fig|83332.1.peg.1405 CDS NC_000962 1580420 1579596 -2 - 825 hypothetical protein Rv1403c - none - gi|15608541 fig|83332.1.peg.1406 CDS NC_000962 1580589 1581071 3 + 483 Transcriptional regulator, MarR family - none - gi|15608542 fig|83332.1.peg.1407 CDS NC_000962 1581967 1581143 -1 - 825 hypothetical protein Rv1405c - none - gi|15608543 fig|83332.1.peg.1408 CDS NC_000962 1582164 1583102 3 + 939 Methionyl-tRNA formyltransferase (EC 2.1.2.9) Conserved gene cluster associated with Met-tRNA formyltransferase;
Folate Biosynthesis;
Translation initiation factors bacterial gi|15608544 fig|83332.1.peg.1409 CDS NC_000962 1583099 1584472 2 + 1374 16S rRNA (cytosine(967)-C(5))-methyltransferase (EC 2.1.1.176) Conserved gene cluster associated with Met-tRNA formyltransferase;
RNA methylation gi|15608545 fig|83332.1.peg.1410 CDS NC_000962 1584497 1585195 2 + 699 Ribulose-phosphate 3-epimerase (EC 5.1.3.1) 2-phosphoglycolate salvage;
Conserved gene cluster associated with Met-tRNA formyltransferase;
Pentose phosphate pathway;
Riboflavin synthesis cluster gi|15608546 fig|83332.1.peg.1411 CDS NC_000962 1585192 1586211 1 + 1020 Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193) Riboflavin, FMN and FAD metabolism;
Riboflavin, FMN and FAD metabolism;
Riboflavin, FMN and FAD metabolism in plants;
Riboflavin, FMN and FAD metabolism in plants;
Riboflavin synthesis cluster;
Riboflavin synthesis cluster;
dNTP triphosphohydrolase protein family;
dNTP triphosphohydrolase protein family gi|15608547 fig|83332.1.peg.1412 CDS NC_000962 1587764 1586208 -2 - 1557 hypothetical protein Rv1410c - none - gi|15608548 fig|83332.1.peg.1413 CDS NC_000962 1588480 1587770 -1 - 711 Lipoprotein lprG precursor - none - gi|15608549 fig|83332.1.peg.1414 CDS NC_000962 1588565 1589170 2 + 606 Riboflavin synthase eubacterial/eukaryotic (EC 2.5.1.9) Riboflavin, FMN and FAD metabolism;
Riboflavin, FMN and FAD metabolism in plants;
Riboflavin synthesis cluster;
riboflavin to FAD gi|15608550 fig|83332.1.peg.1415 CDS NC_000962 1589384 1589899 2 + 516 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Low Specificity D-Threonine Aldolase-like - none - gi|15608551 fig|83332.1.peg.1416 CDS NC_000962 1589889 1590290 3 + 402 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Low Specificity D-Threonine Aldolase-like - none - gi|15608552 fig|83332.1.peg.1417 CDS NC_000962 1590395 1591672 2 + 1278 3,4-dihydroxy-2-butanone 4-phosphate synthase (EC 4.1.99.12) / GTP cyclohydrolase II (EC 3.5.4.25) Molybdenum cofactor biosynthesis;
Riboflavin, FMN and FAD metabolism;
Riboflavin, FMN and FAD metabolism;
Riboflavin, FMN and FAD metabolism in plants;
Riboflavin, FMN and FAD metabolism in plants;
Riboflavin synthesis cluster;
Riboflavin synthesis cluster;
riboflavin to FAD gi|15608553 fig|83332.1.peg.1418 CDS NC_000962 1591687 1592151 1 + 465 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.78) Riboflavin, FMN and FAD metabolism;
Riboflavin, FMN and FAD metabolism in plants;
Riboflavin synthesis cluster;
dNTP triphosphohydrolase protein family gi|15608554 fig|83332.1.peg.1419 CDS NC_000962 1592148 1592612 3 + 465 hypothetical protein Rv1417 - none - gi|15608555 fig|83332.1.peg.1420 CDS NC_000962 1592637 1593323 3 + 687 (MTCY21B4.36), len: 228. Unknown. Probable lipoprotein. Contains N-terminal signal sequence and appropriately positioned prokaryotic lipoprotein lipid attachmentsite (PS00013) - none - gi|15608556 fig|83332.1.peg.1421 CDS NC_000962 1593503 1593976 2 + 474 hypothetical protein Rv1419 - none - gi|15608557 fig|83332.1.peg.1422 CDS NC_000962 1594040 1595980 2 + 1941 Excinuclease ABC subunit C DNA repair, UvrABC system gi|15608558 fig|83332.1.peg.1423 CDS NC_000962 1595977 1596882 1 + 906 FIG000506: Predicted P-loop-containing kinase Cluster containing CofD-like protein and co-occuring with DNA repair gi|15608559 fig|83332.1.peg.1424 CDS NC_000962 1596879 1597907 3 + 1029 FIG002813: LPPG:FO 2-phospho-L-lactate transferase like, CofD-like Cluster containing CofD-like protein and co-occuring with DNA repair gi|15608560 fig|83332.1.peg.1425 CDS NC_000962 1597904 1598881 2 + 978 FIG001886: Cytoplasmic hypothetical protein Cluster containing CofD-like protein and co-occuring with DNA repair gi|15608561 fig|83332.1.peg.1426 CDS NC_000962 1599652 1598891 -1 - 762 FIG00820381: hypothetical protein - none - gi|15608562 fig|83332.1.peg.1427 CDS NC_000962 1599656 1601035 2 + 1380 Diacyglycerol O-acyltransferase (EC 2.3.1.20) - none - gi|15608563 fig|83332.1.peg.1428 CDS NC_000962 1602319 1601057 -1 - 1263 Esterase LipO - none - gi|15608564 fig|83332.1.peg.1429 CDS NC_000962 1603926 1602319 -3 - 1608 Long-chain fatty-acid-CoA ligase (EC 6.2.1.3), Mycobacterial subgroup FadD12 Biotin biosynthesis;
Fatty acid metabolism cluster gi|15608565 fig|83332.1.peg.1430 CDS NC_000962 1604757 1603930 -3 - 828 hypothetical protein Rv1428c - none - gi|15608566 fig|83332.1.peg.1431 CDS NC_000962 1604876 1606144 2 + 1269 hypothetical protein Rv1429 - none - gi|15608567 fig|83332.1.peg.1432 CDS NC_000962 1606384 1607970 1 + 1587 (MTCY493.24c), len: 528. N-terminus is highly similar to the conserved N-terminus of the M. tuberculosis PE family of proteins, eg. Y0D4_MYCTU Q50594 (55.9% identity in 127 aa overlap), although the glycine-rich C-terminal region is not present. The C-terminus shows similarity to a hypothetical M. leprae protein Q49633 LEPB1170_F3_112 (391 aa), fasta scores; opt: 342 z-score: 370.7 E(): 1.2e-13, 29.8% identity in 292 aa overlap, and to M. tuberculosis proteins MTCI5.25c and MTCI5.26c - none - gi|15608568 fig|83332.1.peg.1433 CDS NC_000962 1608081 1609850 3 + 1770 hypothetical protein Rv1431 - none - gi|15608569 fig|83332.1.peg.1434 CDS NC_000962 1609847 1611268 2 + 1422 Phytoene dehydrogenase and related proteins Carotenoids gi|15608570 fig|83332.1.peg.1435 CDS NC_000962 1611432 1612247 3 + 816 hypothetical protein Rv1433 - none - gi|15608571 fig|83332.1.peg.1436 CDS NC_000962 1612254 1612391 3 + 138 hypothetical protein Rv1434 - none - gi|15608572 fig|83332.1.peg.1437 CDS NC_000962 1612948 1612340 -1 - 609 hypothetical protein Rv1435c - none - gi|15608573 fig|83332.1.peg.1438 CDS NC_000962 1613305 1614324 1 + 1020 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) Glutaredoxins;
Glycolysis and Gluconeogenesis;
Pyridoxin (Vitamin B6) Biosynthesis;
Redox-dependent regulation of nucleus processes gi|15608574 fig|83332.1.peg.1439 CDS NC_000962 1614327 1615565 3 + 1239 Phosphoglycerate kinase (EC 2.7.2.3) Glycolysis and Gluconeogenesis gi|15608575 fig|83332.1.peg.1440 CDS NC_000962 1615562 1616347 2 + 786 Triosephosphate isomerase (EC 5.3.1.1) CBSS-331978.3.peg.2915;
Glycolysis and Gluconeogenesis gi|15608576 fig|83332.1.peg.1441 CDS NC_000962 1617384 1616959 -3 - 426 hypothetical protein Rv1439c - none - gi|15608577 fig|83332.1.peg.1442 CDS NC_000962 1617715 1618068 1 + 354 Preprotein translocase subunit SecG (TC 3.A.5.1.1) CBSS-331978.3.peg.2915 gi|15608578 fig|83332.1.peg.1443 CDS NC_000962 1619682 1618207 -3 - 1476 PE family protein - none - gi|15608579 fig|83332.1.peg.1444 CDS NC_000962 1619789 1622089 2 + 2301 Biotin sulfoxide reductase (EC 1.-.-.-) / Free methionine-(S)-sulfoxide reductase - none - gi|15608580 fig|83332.1.peg.1445 CDS NC_000962 1622690 1622205 -2 - 486 hypothetical protein Rv1443c - none - gi|15608581 fig|83332.1.peg.1446 CDS NC_000962 1623695 1623285 -2 - 411 hypothetical protein Rv1444c - none - gi|15608582 fig|83332.1.peg.1447 CDS NC_000962 1624455 1623712 -3 - 744 6-phosphogluconolactonase (EC 3.1.1.31), eukaryotic type Pentose phosphate pathway gi|15608583 fig|83332.1.peg.1448 CDS NC_000962 1625363 1624452 -2 - 912 OpcA, an allosteric effector of glucose-6-phosphate dehydrogenase, actinobacterial Pentose phosphate pathway gi|15608584 fig|83332.1.peg.1449 CDS NC_000962 1626960 1625416 -3 - 1545 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) Glycolysis and Gluconeogenesis;
Pentose phosphate pathway gi|15608585 fig|83332.1.peg.1450 CDS NC_000962 1628078 1626957 -2 - 1122 Transaldolase (EC 2.2.1.2) Pentose phosphate pathway gi|15608586 fig|83332.1.peg.1451 CDS NC_000962 1630197 1628095 -3 - 2103 Transketolase (EC 2.2.1.1) Pentose phosphate pathway gi|15608587 fig|83332.1.peg.1452 CDS NC_000962 1634625 1630636 -3 - 3990 PE_PGRS family protein - none - gi|15608588 fig|83332.1.peg.1453 CDS NC_000962 1635027 1635953 3 + 927 Heme O synthase, protoheme IX farnesyltransferase (EC 2.5.1.-) COX10-CtaB Biogenesis of cytochrome c oxidases;
CBSS-196164.1.peg.1690;
CBSS-316057.3.peg.563 gi|15608589 fig|83332.1.peg.1454 CDS NC_000962 1638227 1636002 -2 - 2226 PE_PGRS family protein - none - gi|15608590 fig|83332.1.peg.1455 CDS NC_000962 1638346 1639644 1 + 1299 hypothetical protein Rv1453 - none - gi|15608591 fig|83332.1.peg.1456 CDS NC_000962 1640658 1639672 -3 - 987 Quinone oxidoreductase (EC 1.6.5.5) Quinone oxidoreductase family gi|15608592 fig|83332.1.peg.1457 CDS NC_000962 1640678 1641541 2 + 864 hypothetical protein Rv1455 - none - gi|15608593 fig|83332.1.peg.1458 CDS NC_000962 1642423 1641491 -1 - 933 Cytochrome oxidase assembly protein - none - gi|15608594 fig|83332.1.peg.1459 CDS NC_000962 1643320 1642535 -1 - 786 ABC-type multidrug transport system, permease component CBSS-196164.1.peg.1690 gi|15608595 fig|83332.1.peg.1460 CDS NC_000962 1644258 1643317 -3 - 942 ABC-type multidrug transport system, ATPase component CBSS-196164.1.peg.1690 gi|15608596 fig|83332.1.peg.1461 CDS NC_000962 1646136 1644361 -3 - 1776 integral membrane protein - none - gi|15608597 fig|83332.1.peg.1462 CDS NC_000962 1646154 1646990 3 + 837 Iron-sulfur cluster regulator SufR CBSS-196164.1.peg.1690 gi|15608598 fig|83332.1.peg.1463 CDS NC_000962 1646987 1649527 2 + 2541 Iron-sulfur cluster assembly protein SufB @ intein-containing CBSS-196164.1.peg.1690;
Inteins;
tRNA modification Bacteria gi|15608599 fig|83332.1.peg.1464 CDS NC_000962 1649524 1650717 1 + 1194 Iron-sulfur cluster assembly protein SufD CBSS-196164.1.peg.1690;
tRNA modification Bacteria gi|15608600 fig|83332.1.peg.1465 CDS NC_000962 1650714 1651514 3 + 801 Iron-sulfur cluster assembly ATPase protein SufC CBSS-196164.1.peg.1690;
tRNA modification Bacteria gi|15608601 fig|83332.1.peg.1466 CDS NC_000962 1651516 1652769 1 + 1254 Cysteine desulfurase (EC 2.8.1.7), SufS subfamily Alanine biosynthesis;
mnm5U34 biosynthesis bacteria;
tRNA modification Bacteria gi|15608602 fig|83332.1.peg.1467 CDS NC_000962 1652766 1653254 3 + 489 Putative iron-sulfur cluster assembly scaffold protein for SUF system, SufE2 - none - gi|15608603 fig|83332.1.peg.1468 CDS NC_000962 1653229 1653576 1 + 348 PaaD-like protein (DUF59) involved in Fe-S cluster assembly - none - gi|15608604 fig|83332.1.peg.1469 CDS NC_000962 1655500 1653671 -1 - 1830 Acyl-CoA dehydrogenase (EC 1.3.8.7) - none - gi|15608605 fig|83332.1.peg.1470 CDS NC_000962 1656719 1655607 -2 - 1113 (MTV007.15c), len: 370. Member of Gly-richPE family, subfamily PGRS. TBparse score is 0.856 - none - gi|15608606 fig|83332.1.peg.1471 CDS NC_000962 1656961 1658934 1 + 1974 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) Copper Transport System;
Copper homeostasis;
Terminal cytochrome C oxidases gi|15608607 fig|83332.1.peg.1472 CDS NC_000962 1658978 1659352 2 + 375 Thioredoxin - none - gi|15608608 fig|83332.1.peg.1473 CDS NC_000962 1659368 1659739 2 + 372 Thioredoxin - none - gi|15608609 fig|83332.1.peg.1474 CDS NC_000962 1659761 1660618 2 + 858 Enoyl-CoA hydratase (EC 4.2.1.17) - none - gi|15608610 fig|83332.1.peg.1475 CDS NC_000962 1660654 1662282 1 + 1629 hypothetical protein Rv1473 - none - gi|15608611 fig|83332.1.peg.1476 CDS NC_000962 1663202 1662639 -2 - 564 Transcriptional regulator, TetR family - none - gi|15608612 fig|83332.1.peg.1477 CDS NC_000962 1666044 1663213 -3 - 2832 Aconitate hydratase (EC 4.2.1.3) @ 2-methylisocitrate dehydratase (EC 4.2.1.99) Biogenesis of c-type cytochromes;
Glyoxylate bypass;
Methylcitrate cycle;
Propionate-CoA to Succinate Module;
Propionate-CoA to Succinate Module;
Serine-glyoxylate cycle;
TCA Cycle gi|15608613 fig|83332.1.peg.1478 CDS NC_000962 1666202 1666762 2 + 561 hypothetical protein Rv1476 - none - gi|15608614 fig|83332.1.peg.1479 CDS NC_000962 1666988 1668406 2 + 1419 NLP/P60 family protein - none - gi|15608615 fig|83332.1.peg.1480 CDS NC_000962 1668417 1669142 3 + 726 hypothetical protein Rv1478 - none - gi|15608616 fig|83332.1.peg.1481 CDS NC_000962 1669281 1670414 3 + 1134 hypothetical protein - none - gi|15608617 fig|83332.1.peg.1482 CDS NC_000962 1670411 1671364 2 + 954 hypothetical protein Rv1480 - none - gi|15608618 fig|83332.1.peg.1483 CDS NC_000962 1671375 1672382 3 + 1008 hypothetical protein Rv1481 - none - gi|15608619 fig|83332.1.peg.1484 CDS NC_000962 1673474 1672455 -2 - 1020 hypothetical protein Rv1482c - none - gi|15608620 fig|83332.1.peg.1485 CDS NC_000962 1673438 1674181 2 + 744 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) CBSS-164757.7.peg.5020;
CBSS-246196.1.peg.364;
Fatty Acid Biosynthesis FASII gi|15608621 fig|83332.1.peg.1486 CDS NC_000962 1674200 1675009 2 + 810 Enoyl-[acyl-carrier-protein] reductase [NADH] (EC 1.3.1.9) Fatty Acid Biosynthesis FASII gi|15608622 fig|83332.1.peg.1487 CDS NC_000962 1675015 1676049 1 + 1035 Ferrochelatase, protoheme ferro-lyase (EC 4.99.1.1) Biogenesis of c-type cytochromes;
Heme and Siroheme Biosynthesis gi|15608623 fig|83332.1.peg.1488 CDS NC_000962 1676923 1676015 -1 - 909 hypothetical protein Rv1486c - none - gi|15608624 fig|83332.1.peg.1489 CDS NC_000962 1676939 1677373 2 + 435 Putative activity regulator of membrane protease YbbK - none - gi|15608625 fig|83332.1.peg.1490 CDS NC_000962 1677395 1678540 2 + 1146 Putative stomatin/prohibitin-family membrane protease subunit YbbK - none - gi|15608626 fig|83332.1.peg.1491 CDS NC_000962 1678902 1678576 -3 - 327 hypothetical protein Rv1489c - none - gi|15608627 fig|83332.1.peg.1492 CDS NC_000962 1679320 1680627 1 + 1308 hypothetical protein Rv1490 - none - gi|15608628 fig|83332.1.peg.1493 CDS NC_000962 1681964 1681206 -2 - 759 DedA family protein paralog DedA family of inner membrane proteins gi|15608629 fig|83332.1.peg.1494 CDS NC_000962 1682155 1684002 1 + 1848 Methylmalonyl-CoA mutase, small subunit (EC 5.4.99.2) G3E family of P-loop GTPases (metallocenter biosynthesis);
Serine-glyoxylate cycle gi|15608630 fig|83332.1.peg.1495 CDS NC_000962 1684003 1686255 1 + 2253 Methylmalonyl-CoA mutase large subunit, MutB (EC 5.4.99.2) G3E family of P-loop GTPases (metallocenter biosynthesis);
Serine-glyoxylate cycle gi|15608631 fig|83332.1.peg.1496 CDS NC_000962 1686269 1686571 2 + 303 hypothetical protein Rv1494 - none - gi|15608632 fig|83332.1.peg.1497 CDS NC_000962 1686568 1686885 1 + 318 hypothetical protein Rv1495 - none - gi|15608633 fig|83332.1.peg.1498 CDS NC_000962 1686882 1687886 3 + 1005 putative periplasmic protein kinase ArgK and related GTPases of G3E family G3E family of P-loop GTPases (metallocenter biosynthesis) gi|15608634 fig|83332.1.peg.1499 CDS NC_000962 1687939 1689228 1 + 1290 Esterase A - none - gi|15608635 fig|83332.1.peg.1500 CDS NC_000962 1689918 1689301 -3 - 618 hypothetical protein Rv1498c - none - gi|15608636 fig|83332.1.peg.1501 CDS NC_000962 1690333 1690803 1 + 471 hypothetical protein Rv1499 - none - gi|15608637 fig|83332.1.peg.1502 CDS NC_000962 1690848 1691876 3 + 1029 Glycosyl transferase, family 2 WhiB and WhiB-type regulatory proteins gi|15608638 fig|83332.1.peg.1503 CDS NC_000962 1691888 1692709 2 + 822 hypothetical protein Rv1501 - none - gi|15608639 fig|83332.1.peg.1504 CDS NC_000962 1692922 1693821 1 + 900 hypothetical protein Rv1502 - none - gi|15608640 fig|83332.1.peg.1505 CDS NC_000962 1694542 1693994 -1 - 549 hypothetical protein Rv1503c - none - gi|15608641 fig|83332.1.peg.1506 CDS NC_000962 1695142 1694543 -1 - 600 hypothetical protein Rv1504c - none - gi|15608642 fig|83332.1.peg.1507 CDS NC_000962 1695944 1695279 -2 - 666 hypothetical protein Rv1505c - none - gi|15608643 fig|83332.1.peg.1508 CDS NC_000962 1696441 1695941 -1 - 501 hypothetical protein Rv1506c - none - gi|15608644 fig|83332.1.peg.1509 CDS NC_000962 1697420 1696725 -2 - 696 hypothetical protein Rv1507c - none - gi|15608645 fig|83332.1.peg.1510 CDS NC_000962 1699892 1698093 -2 - 1800 hypothetical protein Rv1508c - none - gi|15608646 fig|83332.1.peg.1511 CDS NC_000962 1700210 1701091 2 + 882 hypothetical protein Rv1509 - none - gi|15608647 fig|83332.1.peg.1512 CDS NC_000962 1701293 1702591 2 + 1299 Possible membrane protein - none - gi|15608648 fig|83332.1.peg.1513 CDS NC_000962 1703072 1704094 2 + 1023 (MTCY277.33), gmdA, len: 340. Probable GDP-D-mannose dehydratase, similar to e.g. PSEUDOMONAS AERUGINOSA G755218 GDP-D-MANNOSE DEHYDRATASE (GCA) (323 aa), fastascores, opt: 1073, z-score: 1269.9 E(): 0, (51.9% identityin320 aa overlap) and to S74433 GDP-D-mannose dehydrataserfbD- Syn (362 aa)opt: 1405; E(): 0; 63.9% identity in 327 aaoverlap - none - gi|15608649 fig|83332.1.peg.1514 CDS NC_000962 1704091 1705059 1 + 969 GDP-L-fucose synthetase (EC 1.1.1.271) - none - gi|15608650 fig|83332.1.peg.1515 CDS NC_000962 1705056 1705787 3 + 732 hypothetical protein Rv1513 - none - gi|15608651 fig|83332.1.peg.1516 CDS NC_000962 1706593 1705805 -1 - 789 hypothetical protein Rv1514c - none - gi|15608652 fig|83332.1.peg.1517 CDS NC_000962 1707524 1706628 -2 - 897 hypothetical protein Rv1515c - none - gi|15608653 fig|83332.1.peg.1518 CDS NC_000962 1708648 1707527 -1 - 1122 hypothetical protein Rv1516c - none - gi|15608654 fig|83332.1.peg.1519 CDS NC_000962 1708869 1709633 3 + 765 hypothetical protein Rv1517 - none - gi|15608655 fig|83332.1.peg.1520 CDS NC_000962 1709642 1710601 2 + 960 Glycosyltransferase PglI (EC 2.4.1.-) - none - gi|15608656 fig|83332.1.peg.1521 CDS NC_000962 1710731 1711000 2 + 270 hypothetical protein Rv1519 - none - gi|15608657 fig|83332.1.peg.1522 CDS NC_000962 1711026 1712066 3 + 1041 Uncharacterized protein Rv1520/MT1570 - none - gi|15608658 fig|83332.1.peg.1523 CDS NC_000962 1712300 1714051 2 + 1752 Fatty-acid-CoA ligase FadD24 - none - gi|15608659 fig|83332.1.peg.1524 CDS NC_000962 1717610 1714170 -2 - 3441 Putative membrane protein MmpL12 - none - gi|15608660 fig|83332.1.peg.1525 CDS NC_000962 1717651 1718694 1 + 1044 Probable methyltransferase (EC 2.1.1.-) - none - gi|15608661 fig|83332.1.peg.1526 CDS NC_000962 1718724 1719968 3 + 1245 Uncharacterized glycosyltransferase Rv1524/MT1575 (EC 2.-.-.-) - none - gi|15608662 fig|83332.1.peg.1527 CDS NC_000962 1720015 1720800 1 + 786 POSSIBLE RHAMNOSYL TRANSFERASE WBBL2 - none - gi|15608663 fig|83332.1.peg.1528 CDS NC_000962 1722058 1720778 -1 - 1281 Uncharacterized protein Rv1526c/MT1577 - none - gi|15608664 fig|83332.1.peg.1529 CDS NC_000962 1728407 1722081 -2 - 6327 Polyketide synthase Pks5 - none - gi|15608665 fig|83332.1.peg.1530 CDS NC_000962 1729448 1728951 -2 - 498 PROBABLE CONSERVED POLYKETIDE SYNTHASE ASSOCIATED PROTEIN PAPA4 - none - gi|15608666 fig|83332.1.peg.1531 CDS NC_000962 1729500 1731254 3 + 1755 Fatty-acid-CoA ligase FadD24 - none - gi|15608667 fig|83332.1.peg.1532 CDS NC_000962 1731371 1732474 2 + 1104 Alcohol dehydrogenase (EC 1.1.1.1) - none - gi|15608668 fig|83332.1.peg.1533 CDS NC_000962 1732471 1733037 1 + 567 Putative uncharacterized protein BCG_1583 - none - gi|15608669 fig|83332.1.peg.1534 CDS NC_000962 1733548 1733114 -1 - 435 Putative uncharacterized protein BCG_1584c - none - gi|15608670 fig|83332.1.peg.1535 CDS NC_000962 1733608 1734735 1 + 1128 2-nitropropane dioxygenase (EC 1.13.11.32) - none - gi|15608671 fig|83332.1.peg.1536 CDS NC_000962 1734732 1735409 3 + 678 Transcriptional regulator, TetR family - none - gi|15608672 fig|83332.1.peg.1537 CDS NC_000962 1735974 1736210 3 + 237 Putative uncharacterized protein BCG_1587 - none - gi|15608673 fig|83332.1.peg.1538 CDS NC_000962 1736517 1739642 3 + 3126 Isoleucyl-tRNA synthetase (EC 6.1.1.5) tRNA aminoacylation, Ile gi|15608674 fig|83332.1.peg.1539 CDS NC_000962 1739854 1741245 1 + 1392 DNA polymerase IV (EC 2.7.7.7) DNA repair, bacterial gi|15608675 fig|83332.1.peg.1540 CDS NC_000962 1742190 1741210 -3 - 981 L-asparaginase (EC 3.5.1.1) Glutamine, Glutamate, Aspartate and Asparagine Biosynthesis gi|15608676 fig|83332.1.peg.1541 CDS NC_000962 1742242 1742850 1 + 609 Lipoprotein signal peptidase (EC 3.4.23.36) Lipoprotein Biosynthesis;
Signal peptidase gi|15608677 fig|83332.1.peg.1542 CDS NC_000962 1742843 1743769 2 + 927 Ribosomal large subunit pseudouridine synthase D (EC 4.2.1.70) RNA pseudouridine syntheses;
Ribosome biogenesis bacterial gi|15608678 fig|83332.1.peg.1543 CDS NC_000962 1744369 1743776 -1 - 594 (MTCY48.24), len: 197. Possible lipoprotein, contains appropriately positioned prokaryotic membrane lipoprotein lipid attachment site (PS0013) - none - gi|15608679 fig|83332.1.peg.1544 CDS NC_000962 1744834 1744424 -1 - 411 Cyanoglobin; Hemoglobin-like protein HbN Bacterial hemoglobins gi|15608680 fig|83332.1.peg.1545 CDS NC_000962 1745062 1746087 1 + 1026 hypothetical protein Rv1543 - none - gi|15608681 fig|83332.1.peg.1546 CDS NC_000962 1746092 1746895 2 + 804 hypothetical protein Rv1544 - none - gi|15608682 fig|83332.1.peg.1547 CDS NC_000962 1746917 1747144 2 + 228 hypothetical protein Rv1545 - none - gi|15608683 fig|83332.1.peg.1548 CDS NC_000962 1747193 1747624 2 + 432 hypothetical protein Rv1546 - none - gi|15608684 fig|83332.1.peg.1549 CDS NC_000962 1747692 1751246 3 + 3555 DNA polymerase III alpha subunit (EC 2.7.7.7) CBSS-350688.3.peg.1509;
Inteins gi|15608685 fig|83332.1.peg.1550 CDS NC_000962 1753331 1751295 -2 - 2037 (MTCY48.17), len: 678. Member of the PPE family, similar to e.g. YHS6_MYCTU P42611 hypothetical 50.6kd protein in hsp65 3' region, (517 aa) FASTA scores, opt:1142, z-score: 1009.6, E(): 0, (40.6% identity in 616 aa overlap) also similar to MTCY31.06c, (54.9% identity in 381 aaoverlap) - none - gi|15608686 fig|83332.1.peg.1551 CDS NC_000962 1753508 1754035 2 + 528 (MTCY48.16c), len: 175. fadD11', Similar tothe N-terminus of many fatty-acid coA ligases e.g. 4CL2_SOLTU P31685 4-coumarate--coa ligase 2 (545 aa), fasta scores;opt: 168 z-score: 238.4 E(): 4.4e-06, 30.4% identity in 112aa overlap possible frameshift with respect to next ORF (MTCY48.15c) but we can find no sequence error to account forthis - none - gi|15608687 fig|83332.1.peg.1552 CDS NC_000962 1753714 1755429 1 + 1716 Long-chain fatty-acid-CoA ligase (EC 6.2.1.3), Mycobacterial subgroup FadD11 - none - gi|15608688 fig|83332.1.peg.1553 CDS NC_000962 1755443 1757308 2 + 1866 Glycerol-3-phosphate acyltransferase (EC 2.3.1.15) - none - gi|15608689 fig|83332.1.peg.1554 CDS NC_000962 1757679 1759430 3 + 1752 Succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1) Serine-glyoxylate cycle;
Succinate dehydrogenase;
TCA Cycle gi|15608690 fig|83332.1.peg.1555 CDS NC_000962 1759433 1760176 2 + 744 Succinate dehydrogenase iron-sulfur protein (EC 1.3.99.1) 5-FCL-like protein;
Serine-glyoxylate cycle;
Succinate dehydrogenase;
TCA Cycle gi|15608691 fig|83332.1.peg.1556 CDS NC_000962 1760173 1760553 1 + 381 Fumarate reductase subunit C Succinate dehydrogenase gi|15608692 fig|83332.1.peg.1557 CDS NC_000962 1760550 1760927 3 + 378 Fumarate reductase subunit D Succinate dehydrogenase gi|15608693 fig|83332.1.peg.1558 CDS NC_000962 1760995 1761603 1 + 609 Transcriptional regulator, TetR family - none - gi|15608694 fig|83332.1.peg.1559 CDS NC_000962 1761742 1762935 1 + 1194 (MTCY48.08c), len: 397. Probable membrane protein, strong similarity to C-terminal part of members oflarge mycobacterial membrane protein family including: MTCY04D9.15c, MTCY08D5.01c, MTCY19G5.06, MTCY20G9.34, etc. FASTAscore: Q11171|YV34_MYCTU HYPOTHETICAL 106.2 KD MEMBRANE P(968 aa) opt: 1722 E(): 0, 69.6% identity in 372 aa overlap - none - gi|15608695 fig|83332.1.peg.1560 CDS NC_000962 1762945 1763391 1 + 447 hypothetical protein Rv1558 - none - gi|15608696 fig|83332.1.peg.1561 CDS NC_000962 1763426 1764715 2 + 1290 Threonine dehydratase (EC 4.3.1.19) Branched-Chain Amino Acid Biosynthesis;
Threonine degradation gi|15608697 fig|83332.1.peg.1562 CDS NC_000962 1764753 1764971 3 + 219 hypothetical protein Rv1560 - none - gi|15608698 fig|83332.1.peg.1563 CDS NC_000962 1764977 1765381 2 + 405 hypothetical protein Rv1561 - none - gi|15608699 fig|83332.1.peg.1564 CDS NC_000962 1767140 1765398 -2 - 1743 Malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141) Trehalose Biosynthesis gi|15608700 fig|83332.1.peg.1565 CDS NC_000962 1769430 1767133 -3 - 2298 Malto-oligosyltrehalose synthase (EC 5.4.99.15) Glycogen metabolism;
Maltose and Maltodextrin Utilization;
Trehalose Biosynthesis gi|15608701 fig|83332.1.peg.1566 CDS NC_000962 1771599 1769434 -3 - 2166 Glycogen debranching enzyme (EC 3.2.1.-) Glycogen metabolism;
Trehalose Biosynthesis gi|15608702 fig|83332.1.peg.1567 CDS NC_000962 1773827 1771638 -2 - 2190 O-antigen acetylase - none - gi|15608703 fig|83332.1.peg.1568 CDS NC_000962 1774618 1773926 -1 - 693 hypothetical protein Rv1566c - none - gi|15608704 fig|83332.1.peg.1569 CDS NC_000962 1775142 1774858 -3 - 285 hypothetical protein - none - gi|15608705 fig|83332.1.peg.1570 CDS NC_000962 1775390 1776703 2 + 1314 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) Biotin biosynthesis;
Biotin biosynthesis Experimental;
Biotin synthesis cluster gi|15608706 fig|83332.1.peg.1571 CDS NC_000962 1776700 1777860 1 + 1161 8-amino-7-oxononanoate synthase (EC 2.3.1.47) Biotin biosynthesis;
Biotin biosynthesis Experimental;
Biotin synthesis cluster gi|15608707 fig|83332.1.peg.1572 CDS NC_000962 1777857 1778537 3 + 681 Dethiobiotin synthetase (EC 6.3.3.3) Biotin biosynthesis;
Biotin biosynthesis Experimental;
Biotin synthesis cluster gi|15608708 fig|83332.1.peg.1573 CDS NC_000962 1778537 1779046 2 + 510 hypothetical protein - none - gi|15608709 fig|83332.1.peg.1574 CDS NC_000962 1779275 1779192 -2 - 84 Partial REP13E12 repeat protein - none - gi|15608710 fig|83332.1.peg.1575 CDS NC_000962 1779312 1779722 3 + 411 Probable phiRV1 phage protein - none - gi|15608711 fig|83332.1.peg.1576 CDS NC_000962 1779928 1780239 1 + 312 hypothetical protein Rv1574 - none - gi|15608712 fig|83332.1.peg.1577 CDS NC_000962 1780344 1780697 3 + 354 hypothetical protein Rv1575 - none - gi|15608713 fig|83332.1.peg.1578 CDS NC_000962 1782062 1780641 -2 - 1422 Phage major capsid protein Phage capsid proteins gi|15608714 fig|83332.1.peg.1579 CDS NC_000962 1782582 1782070 -3 - 513 PhiRv1 phage, prohead protease, HK97 family - none - gi|15608715 fig|83332.1.peg.1580 CDS NC_000962 1783226 1782756 -2 - 471 Phage terminase, small subunit, P27 family - none - gi|15608716 fig|83332.1.peg.1581 CDS NC_000962 1783621 1783307 -1 - 315 Probable phiRv1 phage protein - none - gi|15608717 fig|83332.1.peg.1582 CDS NC_000962 1783890 1783618 -3 - 273 Probable phiRv1 phage protein - none - gi|15608718 fig|83332.1.peg.1583 CDS NC_000962 1784299 1783904 -1 - 396 Probable phiRv1 phage protein - none - gi|15608719 fig|83332.1.peg.1584 CDS NC_000962 1785910 1784495 -1 - 1416 DNA primase/helicase, phage-associated - none - gi|15608720 fig|83332.1.peg.1585 CDS NC_000962 1786308 1785910 -3 - 399 Probable phiRv1 phage protein - none - gi|15608721 fig|83332.1.peg.1586 CDS NC_000962 1786526 1786305 -2 - 222 Putative phiRv1 phage protein - none - gi|15608722 fig|83332.1.peg.1587 CDS NC_000962 1787097 1786582 -3 - 516 Putative phiRv1 phage protein - none - gi|15608723 fig|83332.1.peg.1588 CDS NC_000962 1788503 1787094 -2 - 1410 Probable phiRv1 integrase - none - gi|15608724 fig|83332.1.peg.1589 CDS NC_000962 1789161 1788511 -3 - 651 hypothetical protein Rv1587c - none - gi|15608725 fig|83332.1.peg.1590 CDS NC_000962 1789834 1789166 -1 - 669 hypothetical protein Rv1588c - none - gi|15608726 fig|83332.1.peg.1591 CDS NC_000962 1790282 1791331 2 + 1050 Biotin synthase (EC 2.8.1.6) Biotin biosynthesis;
Biotin biosynthesis Experimental;
Biotin synthesis cluster gi|15608727 fig|83332.1.peg.1592 CDS NC_000962 1791332 1791571 2 + 240 hypothetical protein Rv1590 - none - gi|15608728 fig|83332.1.peg.1593 CDS NC_000962 1791568 1792233 1 + 666 hypothetical protein Rv1591 - none - gi|15608729 fig|83332.1.peg.1594 CDS NC_000962 1793738 1792398 -2 - 1341 hypothetical protein Rv1592c - none - gi|15608730 fig|83332.1.peg.1595 CDS NC_000962 1794705 1793995 -3 - 711 Nudix-related transcriptional regulator NrtR NAD and NADP cofactor biosynthesis global gi|15608731 fig|83332.1.peg.1596 CDS NC_000962 1794754 1795803 1 + 1050 Quinolinate synthetase (EC 2.5.1.72) Mycobacterium virulence operon possibly involved in quinolinate biosynthesis;
NAD and NADP cofactor biosynthesis global gi|15608732 fig|83332.1.peg.1597 CDS NC_000962 1795803 1797386 3 + 1584 L-aspartate oxidase (EC 1.4.3.16) Mycobacterium virulence operon possibly involved in quinolinate biosynthesis;
NAD and NADP cofactor biosynthesis global gi|15608733 fig|83332.1.peg.1598 CDS NC_000962 1797386 1798243 2 + 858 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) Mycobacterium virulence operon possibly involved in quinolinate biosynthesis;
NAD and NADP cofactor biosynthesis global gi|15608734 fig|83332.1.peg.1599 CDS NC_000962 1798292 1799050 2 + 759 hypothetical protein Rv1597 - none - gi|15608735 fig|83332.1.peg.1600 CDS NC_000962 1799481 1799071 -3 - 411 hypothetical protein Rv1598c - none - gi|15608736 fig|83332.1.peg.1601 CDS NC_000962 1799581 1800897 1 + 1317 Histidinol dehydrogenase (EC 1.1.1.23) Histidine Biosynthesis gi|15608737 fig|83332.1.peg.1602 CDS NC_000962 1800894 1802036 3 + 1143 Histidinol-phosphate aminotransferase (EC 2.6.1.9) Histidine Biosynthesis gi|15608738 fig|83332.1.peg.1603 CDS NC_000962 1802033 1802665 2 + 633 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) Histidine Biosynthesis gi|15608739 fig|83332.1.peg.1604 CDS NC_000962 1802662 1803282 1 + 621 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) Histidine Biosynthesis gi|15608740 fig|83332.1.peg.1605 CDS NC_000962 1803292 1804029 1 + 738 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16) / Acting phosphoribosylanthranilate isomerase (EC 5.3.1.24) Chorismate: Intermediate for synthesis of Tryptophan, PAPA antibiotics, PABA, 3-hydroxyanthranilate and more.;
Histidine Biosynthesis;
Tryptophan synthesis;
Tryptophan synthesis gi|15608741 fig|83332.1.peg.1606 CDS NC_000962 1804037 1804849 2 + 813 Histidinol-phosphatase [alternative form] (EC 3.1.3.15) Histidine Biosynthesis gi|15608742 fig|83332.1.peg.1607 CDS NC_000962 1804851 1805654 3 + 804 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) Histidine Biosynthesis gi|15608743 fig|83332.1.peg.1608 CDS NC_000962 1805651 1805998 2 + 348 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) Histidine Biosynthesis gi|15608744 fig|83332.1.peg.1609 CDS NC_000962 1806179 1807261 2 + 1083 Calcium/proton antiporter - none - gi|15608745 fig|83332.1.peg.1610 CDS NC_000962 1807760 1807296 -2 - 465 Alkyl hydroperoxide reductase subunit C-like protein Oxidative stress;
Rubrerythrin;
Thioredoxin-disulfide reductase gi|15608746 fig|83332.1.peg.1611 CDS NC_000962 1807901 1809451 2 + 1551 Anthranilate synthase, aminase component (EC 4.1.3.27) # TrpAa Chorismate: Intermediate for synthesis of Tryptophan, PAPA antibiotics, PABA, 3-hydroxyanthranilate and more.;
Tryptophan synthesis gi|15608747 fig|83332.1.peg.1612 CDS NC_000962 1809441 1810148 3 + 708 Tryptophan-associated membrane protein Tryptophan synthesis gi|15608748 fig|83332.1.peg.1613 CDS NC_000962 1810238 1811056 2 + 819 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) Chorismate: Intermediate for synthesis of Tryptophan, PAPA antibiotics, PABA, 3-hydroxyanthranilate and more.;
Tryptophan synthesis gi|15608749 fig|83332.1.peg.1614 CDS NC_000962 1811125 1812357 1 + 1233 Tryptophan synthase beta chain (EC 4.2.1.20) Chorismate: Intermediate for synthesis of Tryptophan, PAPA antibiotics, PABA, 3-hydroxyanthranilate and more.;
Tryptophan synthesis gi|15608750 fig|83332.1.peg.1615 CDS NC_000962 1812357 1813169 3 + 813 Tryptophan synthase alpha chain (EC 4.2.1.20) Chorismate: Intermediate for synthesis of Tryptophan, PAPA antibiotics, PABA, 3-hydroxyanthranilate and more.;
Tryptophan synthesis gi|15608751 fig|83332.1.peg.1616 CDS NC_000962 1813169 1814575 2 + 1407 Prolipoprotein diacylglyceryl transferase (EC 2.4.99.-) Lipoprotein Biosynthesis gi|15608752 fig|83332.1.peg.1617 CDS NC_000962 1815251 1815691 2 + 441 hypothetical protein Rv1615 - none - gi|15608753 fig|83332.1.peg.1618 CDS NC_000962 1815681 1816079 3 + 399 hypothetical protein Rv1616 - none - gi|15608754 fig|83332.1.peg.1619 CDS NC_000962 1816187 1817605 2 + 1419 Pyruvate kinase (EC 2.7.1.40) Glycerate metabolism;
Glycolysis and Gluconeogenesis;
Pyruvate metabolism I: anaplerotic reactions, PEP gi|15608755 fig|83332.1.peg.1620 CDS NC_000962 1817613 1818515 3 + 903 Acyl-CoA thioesterase II (EC 3.1.2.-) Acyl-CoA thioesterase II;
CBSS-1806.1.peg.1285 gi|15608756 fig|83332.1.peg.1621 CDS NC_000962 1818573 1820027 3 + 1455 Putative membrane protein MT1655 - none - gi|15608757 fig|83332.1.peg.1622 CDS NC_000962 1821691 1819961 -1 - 1731 Transport ATP-binding protein CydC Terminal cytochrome d ubiquinol oxidases;
Terminal cytochrome oxidases gi|15608758 fig|83332.1.peg.1623 CDS NC_000962 1823271 1821688 -3 - 1584 Transport ATP-binding protein CydD Terminal cytochrome d ubiquinol oxidases;
Terminal cytochrome oxidases gi|15608759 fig|83332.1.peg.1624 CDS NC_000962 1824398 1823358 -2 - 1041 Cytochrome d ubiquinol oxidase subunit II (EC 1.10.3.-) Bacterial RNA-metabolizing Zn-dependent hydrolases;
Conserved gene cluster associated with Met-tRNA formyltransferase;
Terminal cytochrome d ubiquinol oxidases;
Terminal cytochrome oxidases gi|15608760 fig|83332.1.peg.1625 CDS NC_000962 1825885 1824428 -1 - 1458 Cytochrome d ubiquinol oxidase subunit I (EC 1.10.3.-) Terminal cytochrome d ubiquinol oxidases;
Terminal cytochrome oxidases gi|15608761 fig|83332.1.peg.1626 CDS NC_000962 1826583 1825996 -3 - 588 hypothetical protein Rv1624c - none - gi|15608762 fig|83332.1.peg.1627 CDS NC_000962 1827868 1826612 -1 - 1257 Adenylate cyclase (EC 4.6.1.1) cAMP signaling in bacteria gi|15608763 fig|83332.1.peg.1628 CDS NC_000962 1828178 1828795 2 + 618 hypothetical protein Rv1626 - none - gi|15608764 fig|83332.1.peg.1629 CDS NC_000962 1830071 1828863 -2 - 1209 hypothetical protein Rv1627c - none - gi|15608765 fig|83332.1.peg.1630 CDS NC_000962 1830559 1830068 -1 - 492 hypothetical protein Rv1628c - none - gi|15608766 fig|83332.1.peg.1631 CDS NC_000962 1830663 1833377 3 + 2715 DNA polymerase I (EC 2.7.7.7) DNA Repair Base Excision gi|15608767 fig|83332.1.peg.1632 CDS NC_000962 1833540 1834985 3 + 1446 SSU ribosomal protein S1p Cell division-ribosomal stress proteins cluster;
Ribosome SSU bacterial gi|15608768 fig|83332.1.peg.1633 CDS NC_000962 1835011 1836234 1 + 1224 Dephospho-CoA kinase (EC 2.7.1.24) Coenzyme A Biosynthesis gi|15608769 fig|83332.1.peg.1634 CDS NC_000962 1836828 1836385 -3 - 444 hypothetical protein Rv1632c - none - gi|15608770 fig|83332.1.peg.1635 CDS NC_000962 1837073 1839169 2 + 2097 Excinuclease ABC subunit B DNA repair, UvrABC system gi|15608771 fig|83332.1.peg.1636 CDS NC_000962 1839166 1840581 1 + 1416 hypothetical protein Rv1634 - none - gi|15608772 fig|83332.1.peg.1637 CDS NC_000962 1842240 1840570 -3 - 1671 hypothetical protein Rv1635c - none - gi|15608773 fig|83332.1.peg.1638 CDS NC_000962 1842449 1842889 2 + 441 hypothetical protein Rv1636 - none - gi|15608774 fig|83332.1.peg.1639 CDS NC_000962 1843690 1842896 -1 - 795 metallo-beta-lactamase superfamily protein - none - gi|15608775 fig|83332.1.peg.1640 CDS NC_000962 1843739 1846657 2 + 2919 Excinuclease ABC subunit A DNA repair, UvrABC system gi|15608776 fig|83332.1.peg.1641 CDS NC_000962 1848456 1846987 -3 - 1470 hypothetical protein Rv1639c - none - gi|15608777 fig|83332.1.peg.1642 CDS NC_000962 1852033 1848515 -1 - 3519 Putative membrane protein found fused to lysyl-tRNA synthetase like protein / Lysyl-tRNA synthetase (class II) related protein found fused to membrane protein tRNA aminoacylation, Lys;
tRNA aminoacylation, Lys gi|15608778 fig|83332.1.peg.1643 CDS NC_000962 1852271 1852876 2 + 606 Translation initiation factor 3 Mycobacterium virulence operon involved in protein synthesis (LSU ribosomal proteins);
Translation initiation factors bacterial gi|15608779 fig|83332.1.peg.1644 CDS NC_000962 1852926 1853120 3 + 195 LSU ribosomal protein L35p Mycobacterium virulence operon involved in protein synthesis (LSU ribosomal proteins);
Ribosome LSU bacterial gi|15608780 fig|83332.1.peg.1645 CDS NC_000962 1853182 1853571 1 + 390 LSU ribosomal protein L20p Mycobacterium virulence operon involved in protein synthesis (LSU ribosomal proteins);
Ribosome LSU bacterial gi|15608781 fig|83332.1.peg.1646 CDS NC_000962 1853604 1854386 3 + 783 RNA methyltransferase, TrmH family tRNA modification Bacteria gi|15608782 fig|83332.1.peg.1647 CDS NC_000962 1855452 1854397 -3 - 1056 hypothetical protein Rv1645c - none - gi|15608783 fig|83332.1.peg.1648 CDS NC_000962 1855762 1856694 1 + 933 PE-PGRS FAMILY PROTEIN - none - gi|15608784 fig|83332.1.peg.1649 CDS NC_000962 1856772 1857722 3 + 951 Purine cyclase-related protein cAMP signaling in bacteria gi|15608785 fig|83332.1.peg.1650 CDS NC_000962 1857729 1858535 3 + 807 hypothetical protein Rv1648 - none - gi|15608786 fig|83332.1.peg.1651 CDS NC_000962 1858731 1859756 3 + 1026 Phenylalanyl-tRNA synthetase alpha chain (EC 6.1.1.20) tRNA aminoacylation, Phe gi|15608787 fig|83332.1.peg.1652 CDS NC_000962 1859756 1862251 2 + 2496 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) tRNA aminoacylation, Phe gi|15608788 fig|83332.1.peg.1653 CDS NC_000962 1865380 1862345 -1 - 3036 PE-PGRS FAMILY PROTEIN - none - gi|15608789 fig|83332.1.peg.1654 CDS NC_000962 1865574 1866632 3 + 1059 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) Arginine Biosynthesis -- gjo;
Arginine Biosynthesis extended gi|15608790 fig|83332.1.peg.1655 CDS NC_000962 1866629 1867843 2 + 1215 Glutamate N-acetyltransferase (EC 2.3.1.35) / N-acetylglutamate synthase (EC 2.3.1.1) Arginine Biosynthesis -- gjo;
Arginine Biosynthesis -- gjo;
Arginine Biosynthesis extended;
Arginine Biosynthesis extended gi|15608791 fig|83332.1.peg.1656 CDS NC_000962 1867840 1868724 1 + 885 Acetylglutamate kinase (EC 2.7.2.8) Arginine Biosynthesis -- gjo;
Arginine Biosynthesis extended gi|15608792 fig|83332.1.peg.1657 CDS NC_000962 1868721 1869923 3 + 1203 Acetylornithine aminotransferase (EC 2.6.1.11) Arginine Biosynthesis -- gjo;
Arginine Biosynthesis extended gi|15608793 fig|83332.1.peg.1658 CDS NC_000962 1869920 1870843 2 + 924 Ornithine carbamoyltransferase (EC 2.1.3.3) Arginine Biosynthesis -- gjo;
Arginine Biosynthesis extended;
Arginine Deiminase Pathway;
Arginine and Ornithine Degradation gi|15608794 fig|83332.1.peg.1659 CDS NC_000962 1870840 1871352 1 + 513 Arginine pathway regulatory protein ArgR, repressor of arg regulon Arginine Biosynthesis -- gjo;
Arginine Biosynthesis extended;
Arginine Deiminase Pathway;
Arginine and Ornithine Degradation gi|15608795 fig|83332.1.peg.1660 CDS NC_000962 1871361 1872557 3 + 1197 Argininosuccinate synthase (EC 6.3.4.5) Arginine Biosynthesis -- gjo;
Arginine Biosynthesis extended gi|15608796 fig|83332.1.peg.1661 CDS NC_000962 1872637 1874049 1 + 1413 Argininosuccinate lyase (EC 4.3.2.1) Arginine Biosynthesis -- gjo;
Arginine Biosynthesis extended gi|15608797 fig|83332.1.peg.1662 CDS NC_000962 1874158 1875219 1 + 1062 Possible chalcone synthase pks10 (EC 2.3.1.74) - none - gi|15608798 fig|83332.1.peg.1663 CDS NC_000962 1875302 1881682 2 + 6381 Probable polyketide synthase pks7 - none - gi|15608799 fig|83332.1.peg.1664 CDS NC_000962 1881702 1886510 3 + 4809 (MTCY275.01-MTCY06H11.27), len: 1602. Probable polyketide synthase, similar to many polyketide synthases eg. ERY2_SACER Q03132 erythronolide synthase, modules 3 and 4 (3567 aa) from Saccharopolyspora erythraea (Streptomyces erythraeus), fasta scores; opt: 3319 z-score: 3345.0 E(): 0, 45.8% identity in 1619 aa overlap. Contains;PS00606 Beta-ketoacyl synthases active site and PS01162 Quinone oxidoreductase/zeta-crystallin signature. Note that the similarity extends into the downstream ORF MTCY275.02, and this could be accounted for by a frameshift between 4764 and 4771,although the sequence has been checked and no discrepancy was found. Also similar to other M. tuberculosis probable polyketide synthases eg. MTCY24G1.03 (59.8% identity in 1144aa overlap) - none - gi|15608800 fig|83332.1.peg.1665 CDS NC_000962 1886510 1888018 2 + 1509 (MTCY275.02), len: 502 aa; Probable polyketide synthase, similar to other polyketide synthases eg. ERY2_SACER Q03132 erythronolide synthase, modules 3 and 4 (3567 aa) from Saccharopolyspora erythraea (Streptomyces erythraeus), fasta scores; opt: 1207 z-score: 1296.2 E(): 0, 43.9% identity in 531 aa overlap. Contains PS00012 Phosphopantetheineattachment site. Note that the similarity extends into the upstream ORF MTCY275.01 and this could be accounted for by a frameshift between 4764 and 4771, although the sequence has been checked and no discrepancy was found. Also similar to other M. tuberculosis probable polyketide synthases eg. MTCY24G1.03 (59.3% identity in 440 aa overlap) - none - gi|15608801 fig|83332.1.peg.1666 CDS NC_000962 1888024 1891077 1 + 3054 (MTCY275.03), len: 1017. Probable polyketide synthase; similar to eg. OL56_STRAT Q07017 oleandomycin polyketide synthase, modules 5 and 6 (3519 aa) from Streptomycesantibioticus, fasta scores; opt: 1767 z-score: 1880.3 E():0, 41.6% identity in 919 aa overlap. Contains PS00012 Phosphopantetheine attachment site. Similar to upstraem ORFMTCY275.03 (49.0% identity in 924 aa overlap), and to otherM.tuberculosis probable polyketide synthases eg. MTCY22G10.01(49.2% identity in 996 aa overlap) - none - gi|15608802 fig|83332.1.peg.1667 CDS NC_000962 1891224 1892285 3 + 1062 (MTCY275.04-MTV047.01), len 353. Some similarity to BCSA_BACSU P54157 putative chalcone synthase (365 aa), fasta scores; opt: 615 z-score: 699.3 E(): 6.2e-32,33.4% identity in 308 aa overlap, and to many plant chalcone synthases eg. CHS_VIGUN P51089 chalcone synthase (ec 2.3.1.74) (388 aa), fasta scores; opt: 391 z-score: 446.1 E():7.8e-18, 27.2% identity in 349 aa overlap. Highly similar to upstream ORF MTCY06H11.25 (72.7% identity in 308 aa overlap) - none - gi|15608803 fig|83332.1.peg.1668 CDS NC_000962 1893560 1892268 -2 - 1293 Cytochrome P450 139 - none - gi|15608804 fig|83332.1.peg.1669 CDS NC_000962 1894228 1893575 -1 - 654 hypothetical protein Rv1667c - none - gi|15608805 fig|83332.1.peg.1670 CDS NC_000962 1895340 1894222 -3 - 1119 hypothetical protein Rv1668c - none - gi|15608806 fig|83332.1.peg.1671 CDS NC_000962 1895723 1896085 2 + 363 hypothetical protein Rv1669 - none - gi|15608807 fig|83332.1.peg.1672 CDS NC_000962 1896118 1896465 1 + 348 hypothetical protein Rv1670 - none - gi|15608808 fig|83332.1.peg.1673 CDS NC_000962 1896473 1896865 2 + 393 hypothetical protein Rv1671 - none - gi|15608809 fig|83332.1.peg.1674 CDS NC_000962 1898205 1896874 -3 - 1332 hypothetical protein Rv1672c - none - gi|15608810 fig|83332.1.peg.1675 CDS NC_000962 1899230 1898298 -2 - 933 hypothetical protein Rv1673c - none - gi|15608811 fig|83332.1.peg.1676 CDS NC_000962 1899914 1899258 -2 - 657 Transcriptional regulator, ArsR family cAMP signaling in bacteria gi|15608812 fig|83332.1.peg.1677 CDS NC_000962 1900973 1900239 -2 - 735 transcriptional regulator, Crp/Fnr family Oxidative stress gi|15608813 fig|83332.1.peg.1678 CDS NC_000962 1901045 1901749 2 + 705 hypothetical protein Rv1676 - none - gi|15608814 fig|83332.1.peg.1679 CDS NC_000962 1901746 1902294 1 + 549 Lipoprotein DsbF - none - gi|15608815 fig|83332.1.peg.1680 CDS NC_000962 1902395 1903297 2 + 903 hypothetical protein Rv1678 - none - gi|15608816 fig|83332.1.peg.1681 CDS NC_000962 1903297 1904418 1 + 1122 Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.8.1) - none - gi|15608817 fig|83332.1.peg.1682 CDS NC_000962 1904427 1905251 3 + 825 hypothetical protein - none - gi|15608818 fig|83332.1.peg.1683 CDS NC_000962 1905248 1906240 2 + 993 POSSIBLE MOLYBDOPTERIN BIOSYNTHESIS PROTEIN MOEX - none - gi|15608819 fig|83332.1.peg.1684 CDS NC_000962 1906401 1907318 3 + 918 hypothetical protein Rv1682 - none - gi|15608820 fig|83332.1.peg.1685 CDS NC_000962 1907592 1910591 3 + 3000 acyl-CoA synthase( EC:6.2.1.- ) - none - gi|15608821 fig|83332.1.peg.1686 CDS NC_000962 1910584 1910808 1 + 225 FIG002473: Protein YcaR in KDO2-Lipid A biosynthesis cluster Broadly distributed proteins not in subsystems gi|15608822 fig|83332.1.peg.1687 CDS NC_000962 1911397 1910774 -1 - 624 Transcriptional regulator, TetR family - none - gi|15608823 fig|83332.1.peg.1688 CDS NC_000962 1912079 1911399 -2 - 681 hypothetical protein Rv1686c - none - gi|15608824 fig|83332.1.peg.1689 CDS NC_000962 1912918 1912151 -1 - 768 ABC-type multidrug transport system ATP-binding component yhiH - none - gi|15608825 fig|83332.1.peg.1690 CDS NC_000962 1912977 1913588 3 + 612 hypothetical protein Rv1688 - none - gi|15608826 fig|83332.1.peg.1691 CDS NC_000962 1913600 1914874 2 + 1275 Tyrosyl-tRNA synthetase (EC 6.1.1.1) ## cluster 1 tRNA aminoacylation, Tyr gi|15608827 fig|83332.1.peg.1692 CDS NC_000962 1915525 1915908 1 + 384 lprJ - none - gi|15608828 fig|83332.1.peg.1693 CDS NC_000962 1915947 1916699 3 + 753 hypothetical protein Rv1691 - none - gi|15608829 fig|83332.1.peg.1694 CDS NC_000962 1916696 1917757 2 + 1062 4-nitrophenylphosphatase (EC 3.1.3.41) - none - gi|15608830 fig|83332.1.peg.1695 CDS NC_000962 1917754 1917930 1 + 177 hypothetical protein Rv1693 - none - gi|15608831 fig|83332.1.peg.1696 CDS NC_000962 1917938 1918744 2 + 807 RNA binding methyltransferase FtsJ like # 16S rRNA is a likely substrate CBSS-446462.5.peg.2987;
tRNA modification Bacteria gi|15608832 fig|83332.1.peg.1697 CDS NC_000962 1918744 1919667 1 + 924 NAD kinase (EC 2.7.1.23) CBSS-446462.5.peg.2987;
NAD and NADP cofactor biosynthesis global gi|15608833 fig|83332.1.peg.1698 CDS NC_000962 1919681 1921444 2 + 1764 DNA repair protein RecN CBSS-446462.5.peg.2987;
DNA repair, bacterial gi|15608834 fig|83332.1.peg.1699 CDS NC_000962 1921540 1922721 1 + 1182 FIG005773: conserved membrane protein ML1361 CBSS-446462.5.peg.2987 gi|15608835 fig|83332.1.peg.1700 CDS NC_000962 1922743 1923687 1 + 945 FIG007481: hypothetical protein CBSS-446462.5.peg.2987 gi|15608836 fig|83332.1.peg.1701 CDS NC_000962 1923827 1925587 2 + 1761 CTP synthase (EC 6.3.4.2) CTP synthase (EC 6.3.4.2) cluster;
Ribosome post-transcriptional modification and chromosomal segregation cluster;
pyrimidine conversions gi|15608837 fig|83332.1.peg.1702 CDS NC_000962 1925580 1926203 3 + 624 ADP-ribose pyrophosphatase (EC 3.6.1.13) NAD and NADP cofactor biosynthesis global;
Nudix proteins (nucleoside triphosphate hydrolases);
Ribosome post-transcriptional modification and chromosomal segregation cluster gi|15608838 fig|83332.1.peg.1703 CDS NC_000962 1926200 1927135 2 + 936 Site-specific recombinase XerD Ribosome post-transcriptional modification and chromosomal segregation cluster gi|15608839 fig|83332.1.peg.1704 CDS NC_000962 1928573 1927209 -2 - 1365 hypothetical protein Rv1702c - none - gi|15608840 fig|83332.1.peg.1705 CDS NC_000962 1929719 1929129 -2 - 591 Probable catechol-o-methyltransferase (EC 2.1.1.6) - none - gi|15608841 fig|83332.1.peg.1706 CDS NC_000962 1931454 1929784 -3 - 1671 D-serine/D-alanine/glycine transporter Glycine and Serine Utilization;
Pyruvate Alanine Serine Interconversions gi|15608842 fig|83332.1.peg.1707 CDS NC_000962 1932652 1931495 -1 - 1158 PPE FAMILY PROTEIN - none - gi|15608843 fig|83332.1.peg.1708 CDS NC_000962 1933876 1932692 -1 - 1185 PPE family protein CBSS-164757.7.peg.5020 gi|15608844 fig|83332.1.peg.1709 CDS NC_000962 1934880 1936340 3 + 1461 Sulfate permease Cysteine Biosynthesis gi|15608845 fig|83332.1.peg.1710 CDS NC_000962 1936358 1937314 2 + 957 ParA-like membrane-associated ATPase Ribosome post-transcriptional modification and chromosomal segregation cluster gi|15608846 fig|83332.1.peg.1711 CDS NC_000962 1937311 1938147 1 + 837 Segregation and condensation protein A Ribosome post-transcriptional modification and chromosomal segregation cluster gi|15608847 fig|83332.1.peg.1712 CDS NC_000962 1938144 1938839 3 + 696 Segregation and condensation protein B Ribosome post-transcriptional modification and chromosomal segregation cluster gi|15608848 fig|83332.1.peg.1713 CDS NC_000962 1938836 1939600 2 + 765 Ribosomal large subunit pseudouridine synthase B (EC 4.2.1.70) ## LSU Psi2605 RNA pseudouridine syntheses;
Ribosome post-transcriptional modification and chromosomal segregation cluster gi|15608849 fig|83332.1.peg.1714 CDS NC_000962 1939597 1940289 1 + 693 Cytidylate kinase (EC 2.7.4.25) Ribosome post-transcriptional modification and chromosomal segregation cluster;
pyrimidine conversions gi|15608850 fig|83332.1.peg.1715 CDS NC_000962 1940286 1941677 3 + 1392 GTP-binding protein EngA Ribosome post-transcriptional modification and chromosomal segregation cluster;
Universal GTPases gi|15608851 fig|83332.1.peg.1716 CDS NC_000962 1941851 1942663 2 + 813 hypothetical protein Rv1714 - none - gi|15608852 fig|83332.1.peg.1717 CDS NC_000962 1942657 1943571 1 + 915 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157) Acetyl-CoA fermentation to Butyrate;
Butanol Biosynthesis;
Polyhydroxybutyrate metabolism gi|15608853 fig|83332.1.peg.1718 CDS NC_000962 1943574 1944404 3 + 831 Kynurenine formamidase, bacterial (EC 3.5.1.9) - none - gi|15608854 fig|83332.1.peg.1719 CDS NC_000962 1944404 1944754 2 + 351 hypothetical protein Rv1717 - none - gi|15608855 fig|83332.1.peg.1720 CDS NC_000962 1944807 1945625 3 + 819 FIG00820704: hypothetical protein - none - gi|15608856 fig|83332.1.peg.1721 CDS NC_000962 1945639 1946418 1 + 780 Transcriptional regulator, IclR family - none - gi|15608857 fig|83332.1.peg.1722 CDS NC_000962 1947417 1947028 -3 - 390 Toxin 1, PIN domain Toxin-Antitoxin MT1 gi|15608858 fig|83332.1.peg.1723 CDS NC_000962 1947632 1947414 -2 - 219 Antitoxin 1 Toxin-Antitoxin MT1 gi|15608859 fig|83332.1.peg.1724 CDS NC_000962 1947859 1949343 1 + 1485 hypothetical protein Rv1722 - none - gi|15608860 fig|83332.1.peg.1725 CDS NC_000962 1949340 1950587 3 + 1248 hypothetical protein Rv1723 - none - gi|15608861 fig|83332.1.peg.1726 CDS NC_000962 1951049 1950630 -2 - 420 hypothetical protein Rv1724c - none - gi|15608862 fig|83332.1.peg.1727 CDS NC_000962 1951749 1951039 -3 - 711 Transcriptional regulator, HxlR family - none - gi|15608863 fig|83332.1.peg.1728 CDS NC_000962 1951850 1953235 2 + 1386 hypothetical protein Rv1726 - none - gi|15608864 fig|83332.1.peg.1729 CDS NC_000962 1953268 1953837 1 + 570 hypothetical protein Rv1727 - none - gi|15608865 fig|83332.1.peg.1730 CDS NC_000962 1954632 1953862 -3 - 771 hypothetical protein Rv1728c - none - gi|15608866 fig|83332.1.peg.1731 CDS NC_000962 1955567 1954629 -2 - 939 O-Methyltransferase involved in polyketide biosynthesis - none - gi|15608867 fig|83332.1.peg.1732 CDS NC_000962 1957243 1955690 -1 - 1554 Beta-lactamase (EC 3.5.2.6) Beta-lactamase gi|15608868 fig|83332.1.peg.1733 CDS NC_000962 1957675 1959231 1 + 1557 Succinate-semialdehyde dehydrogenase [NADP+] dependent (Ssdh) gabD2 (Succinate-semialdehyde dehydrogenase [NADP+]-dependent gabD2) - none - gi|15608869 fig|83332.1.peg.1734 CDS NC_000962 1959789 1959241 -3 - 549 Alkyl hydroperoxide reductase and/or thiol-specific antioxidant family (AhpC/TSA) protein - none - gi|15608870 fig|83332.1.peg.1735 CDS NC_000962 1960485 1959853 -3 - 633 FIG030871: hypothetical protein, Rv1733c - none - gi|15608871 fig|83332.1.peg.1736 CDS NC_000962 1961014 1960772 -1 - 243 hypothetical protein - none - gi|15608872 fig|83332.1.peg.1737 CDS NC_000962 1961786 1961289 -2 - 498 Putative C4-dicarboxylate transporter - none - gi|15608873 fig|83332.1.peg.1738 CDS NC_000962 1964184 1962226 -3 - 1959 Respiratory nitrate reductase NarX Mycobacterium virulence operon involved with nitrate dormancy regulon;
Nitrate and nitrite ammonification gi|15608874 fig|83332.1.peg.1739 CDS NC_000962 1965368 1964181 -2 - 1188 Nitrate/nitrite transporter co-occurring with respiratory nitrate reductase Mycobacterium virulence operon involved with nitrate dormancy regulon;
Nitrate and nitrite ammonification gi|15608875 fig|83332.1.peg.1740 CDS NC_000962 1965655 1965939 1 + 285 FIG041371: hypothetical protein, Rv1738/MT1780 Mycobacterium virulence operon involved with nitrate dormancy regulon gi|15608876 fig|83332.1.peg.1741 CDS NC_000962 1967635 1965953 -1 - 1683 Sulfate transporter - none - gi|15608877 fig|83332.1.peg.1742 CDS NC_000962 1967703 1967915 3 + 213 FIG027256: hypothetical protein, Rv1740 - none - gi|15608878 fig|83332.1.peg.1743 CDS NC_000962 1967915 1968163 2 + 249 Toxin 1, PIN domain Toxin-Antitoxin MT1 gi|15608879 fig|83332.1.peg.1744 CDS NC_000962 1968171 1968908 3 + 738 FIG029760: hypothetical protein, Rv1742 - none - gi|15608880 fig|83332.1.peg.1745 CDS NC_000962 1969002 1970702 3 + 1701 Serine/threonine-protein kinase pknE (EC 2.7.11.1) - none - gi|15608881 fig|83332.1.peg.1746 CDS NC_000962 1971388 1970987 -1 - 402 FIG047698: hypothetical protein, Rv1744c - none - gi|15608882 fig|83332.1.peg.1747 CDS NC_000962 1971989 1971378 -2 - 612 Isopentenyl-diphosphate delta-isomerase (EC 5.3.3.2) Isoprenoid Biosynthesis;
Isoprenoid Biosynthesis: Interconversions gi|15608883 fig|83332.1.peg.1748 CDS NC_000962 1972136 1973566 2 + 1431 Probable serine/threonine-protein kinase pknF (EC 2.7.11.1) - none - gi|15608884 fig|83332.1.peg.1749 CDS NC_000962 1973628 1976225 3 + 2598 Probable conserved transmembrane ATP-binding protein ABC transporter - none - gi|15608885 fig|83332.1.peg.1750 CDS NC_000962 1976598 1977329 3 + 732 Putative uncharacterized protein BCG_1787 - none - gi|15608886 fig|83332.1.peg.1751 CDS NC_000962 1977883 1977326 -1 - 558 hypothetical protein Rv1749c - none - gi|15608887 fig|83332.1.peg.1752 CDS NC_000962 1979565 1977967 -3 - 1599 Long-chain fatty-acid-CoA ligase (EC 6.2.1.3), Mycobacterial subgroup FadD1 - none - gi|15608888 fig|83332.1.peg.1753 CDS NC_000962 1979619 1981001 3 + 1383 Putative uncharacterized protein (Hypothetical oxidoreductase) - none - gi|15608889 fig|83332.1.peg.1754 CDS NC_000962 1981128 1981577 3 + 450 hypothetical protein Rv1752 - none - gi|15608890 fig|83332.1.peg.1755 CDS NC_000962 1984773 1981612 -3 - 3162 PPE family protein CBSS-164757.7.peg.5020 gi|15608891 fig|83332.1.peg.1756 CDS NC_000962 1986668 1984977 -2 - 1692 hypothetical protein - none - gi|15608892 fig|83332.1.peg.1757 CDS NC_000962 1987694 1986852 -2 - 843 Phospholipase C 4 (EC 3.1.4.3) - none - gi|15608893 fig|83332.1.peg.1758 CDS NC_000962 1988627 1987743 -2 - 885 Mobile element protein - none - gi|15608894 fig|83332.1.peg.1759 CDS NC_000962 1989004 1988678 -1 - 327 Mobile element protein - none - gi|15608895 fig|83332.1.peg.1760 CDS NC_000962 1989040 1989564 1 + 525 Cutinase Cut1 - none - gi|15608896 fig|83332.1.peg.1761 CDS NC_000962 1992575 1989831 -2 - 2745 PE family protein - none - gi|15608897 fig|83332.1.peg.1762 CDS NC_000962 1993151 1994659 2 + 1509 hypothetical protein Rv1760 - none - gi|15608898 fig|83332.1.peg.1763 CDS NC_000962 1995052 1994669 -1 - 384 hypothetical protein Rv1761c - none - gi|15608899 fig|83332.1.peg.1764 CDS NC_000962 1995840 1995052 -3 - 789 hypothetical protein Rv1762c - none - gi|15608900 fig|83332.1.peg.1765 CDS NC_000962 1996150 1996476 1 + 327 Mobile element protein - none - gi|15608901 fig|83332.1.peg.1766 CDS NC_000962 1996527 1997411 3 + 885 Mobile element protein - none - gi|15608902 fig|83332.1.peg.1767 CDS NC_000962 1998513 1997416 -3 - 1098 HNH endonuclease domain protein - none - gi|15608903 fig|83332.1.peg.1768 CDS NC_000962 1999816 2000004 1 + 189 hypothetical protein Rv1766 - none - gi|15608904 fig|83332.1.peg.1769 CDS NC_000962 2000072 2000431 2 + 360 Possible carboxymuconolactone decarboxylase family protein (EC 4.1.1.44) - none - gi|15608905 fig|83332.1.peg.1770 CDS NC_000962 2000612 2002468 2 + 1857 PE family protein - none - gi|15608906 fig|83332.1.peg.1771 CDS NC_000962 2002624 2003868 1 + 1245 L-gulono-1,4-lactone oxidase (EC 1.1.3.8) - none - gi|15608907 fig|83332.1.peg.1772 CDS NC_000962 2003876 2005162 2 + 1287 Putative aminopeptidase - none - gi|15608908 fig|83332.1.peg.1773 CDS NC_000962 2005159 2006445 1 + 1287 oxidoreductase, FAD-binding - none - gi|15608909 fig|83332.1.peg.1774 CDS NC_000962 2006634 2006945 3 + 312 hypothetical protein Rv1772 - none - gi|15608910 fig|83332.1.peg.1775 CDS NC_000962 2007764 2007018 -2 - 747 Transcriptional regulator, IclR family - none - gi|15608911 fig|83332.1.peg.1776 CDS NC_000962 2007830 2009170 2 + 1341 oxidoreductase, FAD-binding - none - gi|15608912 fig|83332.1.peg.1777 CDS NC_000962 2009170 2009988 1 + 819 FIG00820194: hypothetical protein - none - gi|15608913 fig|83332.1.peg.1778 CDS NC_000962 2010553 2009993 -1 - 561 Transcriptional regulator, TetR family - none - gi|15608914 fig|83332.1.peg.1779 CDS NC_000962 2010654 2011958 3 + 1305 Cytochrome P450 144 - none - gi|15608915 fig|83332.1.peg.1780 CDS NC_000962 2012528 2012079 -2 - 450 hypothetical protein Rv1778c - none - gi|15608916 fig|83332.1.peg.1781 CDS NC_000962 2014477 2012684 -1 - 1794 FIG00821637: hypothetical protein - none - gi|15608917 fig|83332.1.peg.1782 CDS NC_000962 2014697 2015260 2 + 564 FIG00820556: hypothetical protein - none - gi|15608918 fig|83332.1.peg.1783 CDS NC_000962 2017474 2015300 -1 - 2175 4-alpha-glucanotransferase (amylomaltase) (EC 2.4.1.25) Glycogen metabolism;
Maltose and Maltodextrin Utilization gi|15608919 fig|83332.1.peg.1784 CDS NC_000962 2017738 2019258 1 + 1521 Possible membrane protein - none - gi|15608920 fig|83332.1.peg.1785 CDS NC_000962 2019255 2020562 3 + 1308 hypothetical protein Rv1783 - none - gi|15608921 fig|83332.1.peg.1786 CDS NC_000962 2020632 2023430 3 + 2799 hypothetical protein Rv1784 - none - gi|15608922 fig|83332.1.peg.1787 CDS NC_000962 2024626 2023445 -1 - 1182 Cytochrome P450 143 - none - gi|15608923 fig|83332.1.peg.1788 CDS NC_000962 2024826 2025029 3 + 204 Putative ferredoxin - none - gi|15608924 fig|83332.1.peg.1789 CDS NC_000962 2025299 2026396 2 + 1098 (MTV049.09), len: 365. Unknown, similar to members of the PPE family of M. tuberculosis hypothetical proteins, e.g. gp|Z74024|MTCY274_24 M. tuberculosis cosmid (404 aa) FASTA scores:opt: 837 z-score: 879.6 E(): 0; 52.0%identity in 406 aa overlap, also similar to MTCI125_27, MTCI125_26, MTY15C10_31, MTCY10G2_10, MTCY3A2_22, MTCY3C7_24 etc. - none - gi|15608925 fig|83332.1.peg.1790 CDS NC_000962 2026475 2026774 2 + 300 (MTV049.10), len: 99. Unknown but belongs to large family of Gly-, Ala-rich M. tuberculosis proteins (PE family), similar to e.g. gp|Z93777|MTCI364_7 M. tuberculosis cosmid (99 aa), opt: 414 z-score: 497.0 E(): 3.6e-20. 72.4% identity in 98 aa overlapAlso similar to MTV002_35,MTY13E12_30, MTY15C10_30, MTCY10G2_9, MTCY359_33 etc. - none - gi|15608926 fig|83332.1.peg.1791 CDS NC_000962 2026788 2027969 3 + 1182 (MTV049.11), len: 393. Unknown, highly similar to members of the PPE family of M. tuberculosis hypothetical proteins, e.g. gp|Z98268|MTCI125_26 M. tuberculosis cosmid (385 aa) opt: 1283 z-score: 1046.3 E(): 0, 62.7% identity in 408 aa overlap. Also similar to MTV002_34, MTCY10G2_10, MTCI364_8, MTCY02B10_25, MTY13E12_31etc. - none - gi|15608927 fig|83332.1.peg.1792 CDS NC_000962 2028423 2029475 3 + 1053 (MTV049.12), len: 350. Unknown, similar to members of the PPE family of M. tuberculosis hypothetical proteins, e.g. gp|Z74024|MTCY274_24 M. tuberculosis cosmid (404 aa)FASTA scores: opt: 849 z-score: 861.0 E(): 0; 50.0% identity in 406 aa overlap. Also similar to MTCI125_27, MTCI125_26, MTCY10G2_10, MTY15C10_31, MTCY3A2_22, MTV002_34 etc - none - gi|15608928 fig|83332.1.peg.1793 CDS NC_000962 2029902 2030201 3 + 300 FIG018298: PE family protein PPE gene cluster in Mycobacteria gi|15608929 fig|83332.1.peg.1794 CDS NC_000962 2030345 2030641 2 + 297 ESAT-6-like protein EsxJ PPE gene cluster in Mycobacteria gi|15611064 fig|83332.1.peg.1795 CDS NC_000962 2030692 2030976 1 + 285 ESAT-6-like protein EsxN PPE gene cluster in Mycobacteria gi|15608930 fig|83332.1.peg.1796 CDS NC_000962 2031064 2031966 1 + 903 FIG023076: hypothetical protein in PPE gene cluster PPE gene cluster in Mycobacteria gi|15608931 fig|83332.1.peg.1797 CDS NC_000962 2032238 2033749 2 + 1512 Type VII secretion integral membrane protein EccD PPE gene cluster in Mycobacteria gi|15608932 fig|83332.1.peg.1798 CDS NC_000962 2033727 2035484 3 + 1758 Type VII secretion-associated serine protease mycosin PPE gene cluster in Mycobacteria gi|15608933 fig|83332.1.peg.1799 CDS NC_000962 2035481 2036701 2 + 1221 Type VII secretion protein EccE PPE gene cluster in Mycobacteria gi|15608934 fig|83332.1.peg.1800 CDS NC_000962 2036698 2038530 1 + 1833 Type VII secretion AAA-ATPase EccA PPE gene cluster in Mycobacteria gi|15608935 fig|83332.1.peg.1801 CDS NC_000962 2039157 2039348 3 + 192 Lipoprotein LppT - none - gi|15608936 fig|83332.1.peg.1802 CDS NC_000962 2039451 2041418 3 + 1968 FIG013075: PPE family protein CBSS-164757.7.peg.5020;
PPE gene cluster in Mycobacteria gi|15608937 fig|83332.1.peg.1803 CDS NC_000962 2041999 2043270 1 + 1272 FIG013075: PPE family protein CBSS-164757.7.peg.5020;
PPE gene cluster in Mycobacteria gi|15608938 fig|83332.1.peg.1804 CDS NC_000962 2043382 2044773 1 + 1392 FIG013075: PPE family protein CBSS-164757.7.peg.5020;
PPE gene cluster in Mycobacteria gi|15608939 fig|83332.1.peg.1805 CDS NC_000962 2046840 2044921 -3 - 1920 PE-PGRS family protein PPE gene cluster in Mycobacteria gi|15608940 fig|83332.1.peg.1806 CDS NC_000962 2047347 2047021 -3 - 327 FIG00819992: hypothetical protein PPE gene cluster in Mycobacteria gi|15608941 fig|83332.1.peg.1807 CDS NC_000962 2048032 2047685 -1 - 348 hypothetical protein Rv1805c - none - gi|15608942 fig|83332.1.peg.1808 CDS NC_000962 2048070 2048369 3 + 300 FIG018298: PE family protein PPE gene cluster in Mycobacteria gi|15608943 fig|83332.1.peg.1809 CDS NC_000962 2048384 2049595 2 + 1212 FIG013075: PPE family protein PPE gene cluster in Mycobacteria gi|15608944 fig|83332.1.peg.1810 CDS NC_000962 2049919 2051148 1 + 1230 FIG013075: PPE family protein PPE gene cluster in Mycobacteria gi|15608945 fig|83332.1.peg.1811 CDS NC_000962 2051280 2052686 3 + 1407 FIG013075: PPE family protein CBSS-164757.7.peg.5020;
PPE gene cluster in Mycobacteria gi|15608946 fig|83332.1.peg.1812 CDS NC_000962 2052931 2053287 1 + 357 FIG00819992: hypothetical protein PPE gene cluster in Mycobacteria gi|15608947 fig|83332.1.peg.1813 CDS NC_000962 2053441 2054145 1 + 705 Mg(2+) transport ATPase protein C Magnesium transport;
PPE gene cluster in Mycobacteria gi|15608948 fig|83332.1.peg.1814 CDS NC_000962 2055357 2054155 -3 - 1203 NADH dehydrogenase (EC 1.6.99.3) PPE gene cluster in Mycobacteria;
Respiratory dehydrogenases 1;
Riboflavin synthesis cluster gi|15608949 fig|83332.1.peg.1815 CDS NC_000962 2056110 2055679 -3 - 432 Possible membrane protein - none - gi|15608950 fig|83332.1.peg.1816 CDS NC_000962 2056519 2057421 1 + 903 Membrane-bound C-5 sterol desaturase Erg3 - none - gi|15608951 fig|83332.1.peg.1817 CDS NC_000962 2057526 2058191 3 + 666 hypothetical protein Rv1815 - none - gi|15608952 fig|83332.1.peg.1818 CDS NC_000962 2058254 2058958 2 + 705 Transcriptional regulator, TetR family - none - gi|15608953 fig|83332.1.peg.1819 CDS NC_000962 2059593 2061056 3 + 1464 fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal:FAD dependent oxidoreductase Succinate dehydrogenase gi|15608954 fig|83332.1.peg.1820 CDS NC_000962 2062672 2061176 -1 - 1497 PE-PGRS family protein PPE gene cluster in Mycobacteria gi|15608955 fig|83332.1.peg.1821 CDS NC_000962 2064726 2062807 -3 - 1920 Drugs-transport transmembrane ATP-binding protein ABC transporter - none - gi|15608956 fig|83332.1.peg.1822 CDS NC_000962 2064797 2066440 2 + 1644 COG0028: Thiamine pyrophosphate-requiring enzymes - none - gi|15608957 fig|83332.1.peg.1823 CDS NC_000962 2066455 2068881 1 + 2427 Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1) - none - gi|15608958 fig|83332.1.peg.1824 CDS NC_000962 2069078 2069707 2 + 630 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (EC 2.7.8.5) CBSS-1806.1.peg.1285;
Glycerolipid and Glycerophospholipid Metabolism in Bacteria gi|15608959 fig|83332.1.peg.1825 CDS NC_000962 2069700 2070623 3 + 924 FIG030330: hypothetical protein CBSS-227882.1.peg.6980 gi|15608960 fig|83332.1.peg.1826 CDS NC_000962 2070652 2071017 1 + 366 FIG025307: hypothetical protein CBSS-227882.1.peg.6980 gi|15608961 fig|83332.1.peg.1827 CDS NC_000962 2071034 2071912 2 + 879 Division initiation protein CBSS-227882.1.peg.6980 gi|15608962 fig|83332.1.peg.1828 CDS NC_000962 2071950 2072354 3 + 405 Glycine cleavage system H protein Glycine and Serine Utilization;
Glycine cleavage system gi|15608963 fig|83332.1.peg.1829 CDS NC_000962 2072594 2073082 2 + 489 FHA-domain-containing proteins - none - gi|15608964 fig|83332.1.peg.1830 CDS NC_000962 2073079 2073822 1 + 744 Transcriptional regulator, MerR family - none - gi|15608965 fig|83332.1.peg.1831 CDS NC_000962 2073941 2074435 2 + 495 hypothetical protein Rv1829 - none - gi|15608966 fig|83332.1.peg.1832 CDS NC_000962 2074839 2075516 3 + 678 Uncharacterized HTH-type transcriptional regulator - none - gi|15608967 fig|83332.1.peg.1833 CDS NC_000962 2075569 2075826 1 + 258 hypothetical protein Rv1831 - none - gi|15608968 fig|83332.1.peg.1834 CDS NC_000962 2075875 2078700 1 + 2826 Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) Glycine and Serine Utilization;
Glycine cleavage system;
Lipoic acid metabolism gi|15608969 fig|83332.1.peg.1835 CDS NC_000962 2079787 2078927 -1 - 861 Haloalkane dehalogenase 2 (EC 3.8.1.5) - none - gi|15608970 fig|83332.1.peg.1836 CDS NC_000962 2079828 2080694 3 + 867 Hydrolase - none - gi|15608971 fig|83332.1.peg.1837 CDS NC_000962 2082585 2080699 -3 - 1887 Putative hydrolase, CocE/NonD family - none - gi|15608972 fig|83332.1.peg.1838 CDS NC_000962 2084634 2082601 -3 - 2034 hypothetical protein - none - gi|15608973 fig|83332.1.peg.1839 CDS NC_000962 2086979 2084754 -2 - 2226 Malate synthase G (EC 2.3.3.9) Glyoxylate bypass;
Glyoxylate bypass cluster;
Serine-glyoxylate cycle gi|15608974 fig|83332.1.peg.1840 CDS NC_000962 2087650 2087255 -1 - 396 Toxin 1, PIN domain Toxin-Antitoxin MT1 gi|15608975 fig|83332.1.peg.1841 CDS NC_000962 2087910 2087647 -3 - 264 FIG034581: hypothetical protein - none - gi|15608976 fig|83332.1.peg.1842 CDS NC_000962 2089516 2087969 -1 - 1548 PE family protein - none - gi|15608977 fig|83332.1.peg.1843 CDS NC_000962 2090716 2089679 -1 - 1038 Magnesium and cobalt efflux protein CorC Glycyl-tRNA synthetase containing cluster;
Magnesium transport gi|15608978 fig|83332.1.peg.1844 CDS NC_000962 2092083 2090716 -3 - 1368 Magnesium and cobalt efflux protein CorC Glycyl-tRNA synthetase containing cluster;
Magnesium transport gi|15608979 fig|83332.1.peg.1845 CDS NC_000962 2093696 2092257 -2 - 1440 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain Purine conversions;
Purine salvage cluster;
Purine salvage cluster;
WhiB and WhiB-type regulatory proteins gi|15608980 fig|83332.1.peg.1846 CDS NC_000962 2095186 2093729 -1 - 1458 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) Pentose phosphate pathway gi|15608981 fig|83332.1.peg.1847 CDS NC_000962 2096166 2095216 -3 - 951 Peptidase M48, Ste24p precursor - none - gi|15608982 fig|83332.1.peg.1848 CDS NC_000962 2096597 2096181 -2 - 417 Transcriptional regulator, BlaI family - none - gi|15608983 fig|83332.1.peg.1849 CDS NC_000962 2096875 2097297 1 + 423 Putative esterase - none - gi|15608984 fig|83332.1.peg.1850 CDS NC_000962 2097346 2097648 1 + 303 Urease gamma subunit (EC 3.5.1.5) G3E family of P-loop GTPases (metallocenter biosynthesis);
Urea decomposition;
Urease subunits gi|15608985 fig|83332.1.peg.1851 CDS NC_000962 2097645 2097959 3 + 315 Urease beta subunit (EC 3.5.1.5) G3E family of P-loop GTPases (metallocenter biosynthesis);
Urea decomposition;
Urease subunits gi|15608986 fig|83332.1.peg.1852 CDS NC_000962 2097959 2099692 2 + 1734 Urease alpha subunit (EC 3.5.1.5) G3E family of P-loop GTPases (metallocenter biosynthesis);
Urea decomposition;
Urease subunits gi|15608987 fig|83332.1.peg.1853 CDS NC_000962 2099692 2100327 1 + 636 Urease accessory protein UreF G3E family of P-loop GTPases (metallocenter biosynthesis);
Urea decomposition;
Urease subunits gi|15608988 fig|83332.1.peg.1854 CDS NC_000962 2100338 2101012 2 + 675 Urease accessory protein UreG G3E family of P-loop GTPases (metallocenter biosynthesis);
Urea decomposition;
Urease subunits gi|15608989 fig|83332.1.peg.1855 CDS NC_000962 2101020 2101646 3 + 627 Urease accessory protein UreD G3E family of P-loop GTPases (metallocenter biosynthesis);
Urea decomposition;
Urease subunits gi|15608990 fig|83332.1.peg.1856 CDS NC_000962 2103040 2101649 -1 - 1392 NADH dehydrogenase (EC 1.6.99.3) PPE gene cluster in Mycobacteria;
Respiratory dehydrogenases 1;
Riboflavin synthesis cluster gi|15608991 fig|83332.1.peg.1857 CDS NC_000962 2104105 2103182 -1 - 924 Oxidoreductase - none - gi|15608992 fig|83332.1.peg.1858 CDS NC_000962 2104821 2104144 -3 - 678 Oxidoreductase, short-chain dehydrogenase/reductase family - none - gi|15608993 fig|83332.1.peg.1859 CDS NC_000962 2104983 2105768 3 + 786 Molybdenum ABC transporter, periplasmic molybdenum-binding protein ModA (TC 3.A.1.8.1) Molybdenum cofactor biosynthesis gi|15608994 fig|83332.1.peg.1860 CDS NC_000962 2105771 2106565 2 + 795 Molybdenum transport system permease protein ModB (TC 3.A.1.8.1) Molybdenum cofactor biosynthesis gi|15608995 fig|83332.1.peg.1861 CDS NC_000962 2106572 2107681 2 + 1110 Molybdenum transport ATP-binding protein ModC (TC 3.A.1.8.1) Molybdenum cofactor biosynthesis gi|15608996 fig|83332.1.peg.1862 CDS NC_000962 2107734 2108711 3 + 978 Alanine and proline-rich secreted protein Apa, fibronectin attachment protein - none - gi|15608997 fig|83332.1.peg.1863 CDS NC_000962 2109163 2109468 1 + 306 Possible membrane protein - none - gi|15608998 fig|83332.1.peg.1864 CDS NC_000962 2109542 2110582 2 + 1041 Alcohol dehydrogenase (EC 1.1.1.1) Glycerolipid and Glycerophospholipid Metabolism in Bacteria gi|15608999 fig|83332.1.peg.1865 CDS NC_000962 2111359 2110589 -1 - 771 Possible membrane protein - none - gi|15609000 fig|83332.1.peg.1866 CDS NC_000962 2112107 2111352 -2 - 756 Uncharacterized protein conserved in bacteria - none - gi|15609001 fig|83332.1.peg.1867 CDS NC_000962 2112964 2112104 -1 - 861 Oxidoreductase, short-chain dehydrogenase/reductase family - none - gi|15609002 fig|83332.1.peg.1868 CDS NC_000962 2113138 2115474 1 + 2337 Acyl-CoA transferases/carnitine dehydratase - none - gi|15609003 fig|83332.1.peg.1869 CDS NC_000962 2115762 2117246 3 + 1485 Acetyl-CoA acetyltransferase - none - gi|15609004 fig|83332.1.peg.1870 CDS NC_000962 2117345 2119444 2 + 2100 Phosphoenolpyruvate synthase (EC 2.7.9.2) Glycolysis and Gluconeogenesis;
Inteins;
Pyruvate metabolism I: anaplerotic reactions, PEP gi|15609005 fig|83332.1.peg.1871 CDS NC_000962 2120693 2119458 -2 - 1236 Anthranilate dioxygenase reductase - none - gi|15609006 fig|83332.1.peg.1872 CDS NC_000962 2121428 2120793 -2 - 636 FIG00820353: hypothetical protein - none - gi|15609007 fig|83332.1.peg.1873 CDS NC_000962 2121882 2121493 -3 - 390 hypothetical protein Rv1871c - none - gi|15609008 fig|83332.1.peg.1874 CDS NC_000962 2123149 2121905 -1 - 1245 L-lactate dehydrogenase (EC 1.1.2.3) Lactate utilization;
Respiratory dehydrogenases 1 gi|15609009 fig|83332.1.peg.1875 CDS NC_000962 2123172 2123609 3 + 438 NTP pyrophosphohydrolases including oxidative damage repair enzymes - none - gi|15609010 fig|83332.1.peg.1876 CDS NC_000962 2123682 2124368 3 + 687 hypothetical protein Rv1874 - none - gi|15609011 fig|83332.1.peg.1877 CDS NC_000962 2124379 2124822 1 + 444 Pyridoxine 5'-phosphate oxidase - none - gi|15609012 fig|83332.1.peg.1878 CDS NC_000962 2125338 2125817 3 + 480 Bacterioferritin (BFR) - none - gi|15609013 fig|83332.1.peg.1879 CDS NC_000962 2125902 2127965 3 + 2064 EmrB/QacA family drug resistance transporter - none - gi|15609014 fig|83332.1.peg.1880 CDS NC_000962 2128020 2129372 3 + 1353 Glutamine synthetase (EC 6.3.1.2), putative Glutamine synthetases gi|15609015 fig|83332.1.peg.1881 CDS NC_000962 2129375 2130511 2 + 1137 Amidohydrolase - none - gi|15609016 fig|83332.1.peg.1882 CDS NC_000962 2131855 2130539 -1 - 1317 Cytochrome P450 140 - none - gi|15609017 fig|83332.1.peg.1883 CDS NC_000962 2132327 2131905 -2 - 423 Lipoprotein LppE - none - gi|15609018 fig|83332.1.peg.1884 CDS NC_000962 2133201 2132368 -3 - 834 Probable short-chain type dehydrogenase/reductase (EC 1.1.-.-) - none - gi|15609019 fig|83332.1.peg.1885 CDS NC_000962 2133690 2133229 -3 - 462 FIG00820653: hypothetical protein - none - gi|15609020 fig|83332.1.peg.1886 CDS NC_000962 2134259 2133729 -2 - 531 Resuscitation-promoting factor RpfC - none - gi|15609021 fig|83332.1.peg.1887 CDS NC_000962 2134870 2134271 -1 - 600 Periplasmic chorismate mutase I precursor (EC 5.4.99.5) Chorismate Synthesis;
Phenylalanine and Tyrosine Branches from Chorismate gi|15609022 fig|83332.1.peg.1888 CDS NC_000962 2135865 2134888 -3 - 978 Esterase, secreted fibronectin-binding protein antigen 85-B FbpB - none - gi|15609023 fig|83332.1.peg.1889 CDS NC_000962 2136256 2137398 1 + 1143 Possible membrane protein - none - gi|15609024 fig|83332.1.peg.1890 CDS NC_000962 2138077 2137517 -1 - 561 Possible membrane protein - none - gi|15609025 fig|83332.1.peg.1891 CDS NC_000962 2139015 2138659 -3 - 357 O-methyltransferase - none - gi|15609026 fig|83332.1.peg.1892 CDS NC_000962 2139685 2139074 -1 - 612 hypothetical protein Rv1890c - none - gi|15609027 fig|83332.1.peg.1893 CDS NC_000962 2139739 2140146 1 + 408 Possible membrane protein - none - gi|15609028 fig|83332.1.peg.1894 CDS NC_000962 2140163 2140474 2 + 312 hypothetical protein Rv1892 - none - gi|15609029 fig|83332.1.peg.1895 CDS NC_000962 2140484 2140702 2 + 219 hypothetical protein Rv1893 - none - gi|15609030 fig|83332.1.peg.1896 CDS NC_000962 2141867 2140737 -2 - 1131 hypothetical protein Rv1894c - none - gi|15609031 fig|83332.1.peg.1897 CDS NC_000962 2142519 2143673 3 + 1155 Threonine dehydrogenase and related Zn-dependent dehydrogenases Threonine degradation gi|15609032 fig|83332.1.peg.1898 CDS NC_000962 2144444 2143533 -2 - 912 Putative S-adenosyl-L-methionine-dependent methyltransferase - none - gi|15609033 fig|83332.1.peg.1899 CDS NC_000962 2144880 2144449 -3 - 432 D-tyrosyl-tRNA(Tyr) deacylase D-tyrosyl-tRNA(Tyr) deacylase;
Stringent Response, (p)ppGpp metabolism gi|15609034 fig|83332.1.peg.1900 CDS NC_000962 2144938 2145246 1 + 309 ExtraCellular Mutant; Ecm15p - none - gi|15609035 fig|83332.1.peg.1901 CDS NC_000962 2146243 2145212 -1 - 1032 (MTCY180.19), len: 343. Possibly lipoprotein contains appropriately localized lipoprotein lipid attachment site (PS00013). Some similarity to 4-hydroxybutyrate dehydrogenase. FASTA results: Q44020 4-HYDROXYBUTYRATE DEHYDROGENASE (GBD), OR (173 aa) opt: 272; E(): 4.7e-09; 35.8%identity in 165 aa overlap - none - gi|15609036 fig|83332.1.peg.1902 CDS NC_000962 2147631 2146243 -3 - 1389 lignin peroxidase LipJ - none - gi|15609037 fig|83332.1.peg.1903 CDS NC_000962 2147660 2148952 2 + 1293 Molybdopterin binding motif, CinA N-terminal domain / C-terminal domain of CinA type S NAD and NADP cofactor biosynthesis global;
Riboflavin, FMN and FAD metabolism in plants;
Riboflavin, FMN and FAD metabolism in plants;
Riboflavin synthesis cluster;
Universal stress protein family;
Universal stress protein family gi|15609038 fig|83332.1.peg.1904 CDS NC_000962 2150272 2149004 -1 - 1269 Sialic acid-transport integral membrane protein NanT - none - gi|15609039 fig|83332.1.peg.1905 CDS NC_000962 2150362 2150766 1 + 405 Possible membrane protein - none - gi|15609040 fig|83332.1.peg.1906 CDS NC_000962 2150952 2151383 3 + 432 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV - none - gi|15609041 fig|83332.1.peg.1907 CDS NC_000962 2152393 2151431 -1 - 963 D-amino-acid oxidase (EC 1.4.3.3) Proline, 4-hydroxyproline uptake and utilization gi|15609042 fig|83332.1.peg.1908 CDS NC_000962 2152893 2152423 -3 - 471 FIG00823749: hypothetical protein - none - gi|15609043 fig|83332.1.peg.1909 CDS NC_000962 2153880 2153233 -3 - 648 FIG042201: hypothetical protein - none - gi|15609044 fig|83332.1.peg.1910 CDS NC_000962 2156109 2153887 -3 - 2223 Catalase (EC 1.11.1.6) / Peroxidase (EC 1.11.1.7) Oxidative stress;
Oxidative stress;
Protection from Reactive Oxygen Species;
Protection from Reactive Oxygen Species gi|15609045 fig|83332.1.peg.1911 CDS NC_000962 2156599 2156147 -1 - 453 Transcriptional regulator, FUR family Oxidative stress gi|15609046 fig|83332.1.peg.1912 CDS NC_000962 2157297 2156704 -3 - 594 Phosphatidylethanolamine-binding protein - none - gi|15609047 fig|83332.1.peg.1913 CDS NC_000962 2157985 2157380 -1 - 606 Putative lipoprotein LppC, phosphatidylethanolamine-binding protein - none - gi|15609048 fig|83332.1.peg.1914 CDS NC_000962 2159089 2158085 -1 - 1005 Oxidoreductase FadB5 - none - gi|15609049 fig|83332.1.peg.1915 CDS NC_000962 2159189 2159941 2 + 753 Zn-dependent hydrolase, glyoxylase - none - gi|15609050 fig|83332.1.peg.1916 CDS NC_000962 2160326 2159919 -2 - 408 hypothetical protein Rv1914c - none - gi|15609051 fig|83332.1.peg.1917 CDS NC_000962 2160461 2161564 2 + 1104 Isocitrate lyase (EC 4.1.3.1), group III, Mycobacterial type ICL2 # frameshift Glyoxylate bypass gi|15609052 fig|83332.1.peg.1918 CDS NC_000962 2161564 2162760 1 + 1197 Isocitrate lyase (EC 4.1.3.1), group III, Mycobacterial type ICL2 # frameshift Glyoxylate bypass gi|15609053 fig|83332.1.peg.1919 CDS NC_000962 2167240 2162930 -1 - 4311 PPE family protein - none - gi|15609054 fig|83332.1.peg.1920 CDS NC_000962 2170610 2167647 -2 - 2964 PPE family protein - none - gi|15609055 fig|83332.1.peg.1921 CDS NC_000962 2171523 2171059 -3 - 465 hypothetical protein Rv1919c - none - gi|15609056 fig|83332.1.peg.1922 CDS NC_000962 2171621 2172484 2 + 864 Acyltransferase family protein - none - gi|15609057 fig|83332.1.peg.1923 CDS NC_000962 2173793 2172522 -2 - 1272 Lipoprotein LppF - none - gi|15609058 fig|83332.1.peg.1924 CDS NC_000962 2174065 2175180 1 + 1116 hypothetical protein Rv1922 - none - gi|15609059 fig|83332.1.peg.1925 CDS NC_000962 2175171 2176511 3 + 1341 Lipase LipD - none - gi|15609060 fig|83332.1.peg.1926 CDS NC_000962 2176928 2176548 -2 - 381 Putative uncharacterized protein BCG_1963c - none - gi|15609061 fig|83332.1.peg.1927 CDS NC_000962 2177085 2178947 3 + 1863 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) Biotin biosynthesis;
Biotin synthesis cluster;
Fatty acid metabolism cluster gi|15609062 fig|83332.1.peg.1928 CDS NC_000962 2179434 2178955 -3 - 480 Immunogenic protein MPT63/MPB63 precursor - none - gi|15609063 fig|83332.1.peg.1929 CDS NC_000962 2179671 2180444 3 + 774 Putative uncharacterized protein BCG_1966 - none - gi|15609064 fig|83332.1.peg.1930 CDS NC_000962 2181215 2180448 -2 - 768 Probable short-chain type dehydrogenase/reductase (EC 1.-.-.-) - none - gi|15609065 fig|83332.1.peg.1931 CDS NC_000962 2181904 2181260 -1 - 645 hypothetical protein Rv1929c - none - gi|15609066 fig|83332.1.peg.1932 CDS NC_000962 2182440 2181916 -3 - 525 Putative uncharacterized protein BCG_1969c - none - gi|15609067 fig|83332.1.peg.1933 CDS NC_000962 2183237 2182458 -2 - 780 Transcriptional regulator, AraC family - none - gi|15609068 fig|83332.1.peg.1934 CDS NC_000962 2183370 2183867 3 + 498 Thiol peroxidase, Tpx-type (EC 1.11.1.15) Thioredoxin-disulfide reductase gi|15609069 fig|83332.1.peg.1935 CDS NC_000962 2184955 2183864 -1 - 1092 Probable acyl-CoA dehydrogenase fadE18 (EC 1.3.99.-) - none - gi|15609070 fig|83332.1.peg.1936 CDS NC_000962 2186186 2184957 -2 - 1230 Probable acyl-CoA dehydrogenase fadE17 (EC 1.3.99.-) - none - gi|15609071 fig|83332.1.peg.1937 CDS NC_000962 2187157 2186201 -1 - 957 Enoyl-CoA hydratase (EC 4.2.1.17) - none - gi|15609072 fig|83332.1.peg.1938 CDS NC_000962 2187382 2188491 1 + 1110 Monooxygenase component A Predicted mycobacterial monooxygenase gi|15609073 fig|83332.1.peg.1939 CDS NC_000962 2188494 2191013 3 + 2520 Monooxygenase, FAD- and [2Fe-2S]-containing component B Predicted mycobacterial monooxygenase gi|15609074 fig|83332.1.peg.1940 CDS NC_000962 2191025 2192095 2 + 1071 Monooxygenase component C / Probable epoxide hydrolase EphB (EC 3.3.2.9) Predicted mycobacterial monooxygenase gi|15609075 fig|83332.1.peg.1941 CDS NC_000962 2192092 2192607 1 + 516 Oxidoreductase - none - gi|15609076 fig|83332.1.peg.1942 CDS NC_000962 2192604 2193665 3 + 1062 3,4-dihydroxy-2-butanone 4-phosphate synthase (EC 4.1.99.12) / GTP cyclohydrolase II (EC 3.5.4.25) Molybdenum cofactor biosynthesis;
Riboflavin, FMN and FAD metabolism;
Riboflavin, FMN and FAD metabolism;
Riboflavin, FMN and FAD metabolism in plants;
Riboflavin, FMN and FAD metabolism in plants;
Riboflavin synthesis cluster;
Riboflavin synthesis cluster;
riboflavin to FAD gi|15609077 fig|83332.1.peg.1943 CDS NC_000962 2193662 2194432 2 + 771 short-chain type dehydrogenase-reductase - none - gi|15609078 fig|83332.1.peg.1944 CDS NC_000962 2194971 2194642 -3 - 330 Death on curing protein, Doc toxin Phd-Doc, YdcE-YdcD toxin-antitoxin (programmed cell death) systems gi|15609079 fig|83332.1.peg.1945 CDS NC_000962 2195345 2194968 -2 - 378 Prevent host death protein, Phd antitoxin # A Phd-Doc, YdcE-YdcD toxin-antitoxin (programmed cell death) systems gi|15609080 fig|83332.1.peg.1946 CDS NC_000962 2195932 2195342 -1 - 591 FIG033348: hypothetical protein - none - gi|15609081 fig|83332.1.peg.1947 CDS NC_000962 2195987 2197351 2 + 1365 hypothetical protein Rv1945 - none - gi|15609082 fig|83332.1.peg.1948 CDS NC_000962 2197958 2197506 -2 - 453 Prevent host death protein, Phd antitoxin # A Phd-Doc, YdcE-YdcD toxin-antitoxin (programmed cell death) systems gi|15609083 fig|83332.1.peg.1949 CDS NC_000962 2198022 2198423 3 + 402 hypothetical protein Rv1947 - none - gi|15609084 fig|83332.1.peg.1950 CDS NC_000962 2199062 2198712 -2 - 351 hypothetical protein Rv1948c - none - gi|15609085 fig|83332.1.peg.1951 CDS NC_000962 2200032 2199073 -3 - 960 FIG032369: hypothetical protein - none - gi|15609086 fig|83332.1.peg.1952 CDS NC_000962 2200187 2199996 -2 - 192 FIG032435: hypothetical protein - none - gi|15609087 fig|83332.1.peg.1953 CDS NC_000962 2200484 2200188 -2 - 297 hypothetical protein Rv1951c - none - gi|15609088 fig|83332.1.peg.1954 CDS NC_000962 2200724 2200939 2 + 216 hypothetical protein Rv1952 - none - gi|15609089 fig|83332.1.peg.1955 CDS NC_000962 2200936 2201247 1 + 312 hypothetical protein Rv1953 - none - gi|15609090 fig|83332.1.peg.1957 CDS NC_000962 2201582 2202094 2 + 513 hypothetical protein Rv1955 - none - gi|15609092 fig|83332.1.peg.1958 CDS NC_000962 2202136 2202585 1 + 450 hypothetical protein Rv1956 - none - gi|15609093 fig|83332.1.peg.1959 CDS NC_000962 2202582 2203127 3 + 546 hypothetical protein Rv1957 - none - gi|15609094 fig|83332.1.peg.1960 CDS NC_000962 2203630 2203016 -1 - 615 hypothetical protein Rv1958c - none - gi|15609095 fig|83332.1.peg.1961 CDS NC_000962 2203975 2203679 -1 - 297 ParE toxin protein - none - gi|15609096 fig|83332.1.peg.1962 CDS NC_000962 2204223 2203972 -3 - 252 hypothetical protein Rv1960c - none - gi|15609097 fig|83332.1.peg.1963 CDS NC_000962 2204210 2204704 2 + 495 hypothetical protein Rv1961 - none - gi|15609098 fig|83332.1.peg.1964 CDS NC_000962 2205271 2204864 -1 - 408 hypothetical protein Rv1962c - none - gi|15609099 fig|83332.1.peg.1965 CDS NC_000962 2206800 2205580 -3 - 1221 Transcriptional repressor Mce3R, TetR family - none - gi|15609100 fig|83332.1.peg.1966 CDS NC_000962 2207698 2208495 1 + 798 Conserved hypothetical integral membrane protein YrbE3A Mycobacterium virulence operon MCE involved in cell invasion gi|15609101 fig|83332.1.peg.1967 CDS NC_000962 2208505 2209320 1 + 816 Conserved hypothetical integral membrane protein YrbE3B Mycobacterium virulence operon MCE involved in cell invasion gi|15609102 fig|83332.1.peg.1968 CDS NC_000962 2209325 2210602 2 + 1278 MCE-family protein Mce3A Mycobacterium virulence operon MCE involved in cell invasion gi|15609103 fig|83332.1.peg.1969 CDS NC_000962 2210599 2211627 1 + 1029 MCE-family protein Mce3B Mycobacterium virulence operon MCE involved in cell invasion gi|15609104 fig|83332.1.peg.1970 CDS NC_000962 2211624 2212856 3 + 1233 MCE-family protein Mce1C Mycobacterium virulence operon MCE involved in cell invasion gi|15609105 fig|83332.1.peg.1971 CDS NC_000962 2212853 2214124 2 + 1272 MCE-family protein Mce1D Mycobacterium virulence operon MCE involved in cell invasion gi|15609106 fig|83332.1.peg.1972 CDS NC_000962 2214121 2215254 1 + 1134 MCE-family lipoprotein LprK (MCE-family lipoprotein Mce3e) Mycobacterium virulence operon MCE involved in cell invasion gi|15609107 fig|83332.1.peg.1973 CDS NC_000962 2215255 2216568 1 + 1314 MCE-family protein Mce3F Mycobacterium virulence operon MCE involved in cell invasion gi|15609108 fig|83332.1.peg.1974 CDS NC_000962 2216590 2217165 1 + 576 FIG00821219: hypothetical protein - none - gi|15609109 fig|83332.1.peg.1975 CDS NC_000962 2217162 2217644 3 + 483 MCE associated membrane protein - none - gi|15609110 fig|83332.1.peg.1976 CDS NC_000962 2217657 2218034 3 + 378 FIG00820120: hypothetical protein - none - gi|15609111 fig|83332.1.peg.1977 CDS NC_000962 2218050 2218715 3 + 666 hypothetical protein Rv1975 - none - gi|15609112 fig|83332.1.peg.1978 CDS NC_000962 2219249 2218842 -2 - 408 hypothetical protein Rv1976c - none - gi|15609113 fig|83332.1.peg.1979 CDS NC_000962 2219752 2220798 1 + 1047 Zn-dependent protease with chaperone function - none - gi|15609114 fig|83332.1.peg.1980 CDS NC_000962 2220906 2221754 3 + 849 hypothetical protein Rv1978 - none - gi|15609115 fig|83332.1.peg.1981 CDS NC_000962 2223162 2221717 -3 - 1446 Amino acid permease - none - gi|15609116 fig|83332.1.peg.1982 CDS NC_000962 2224027 2223341 -1 - 687 Immunogenic protein MPT64/MPB64 precursor - none - gi|15609117 fig|83332.1.peg.1983 CDS NC_000962 2225186 2224218 -2 - 969 Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1) Ribonucleotide reduction gi|15609118 fig|83332.1.peg.1984 CDS NC_000962 2225830 2225411 -1 - 420 Toxin 1, PIN domain Toxin-Antitoxin MT1 gi|15609119 fig|83332.1.peg.1985 CDS NC_000962 2226242 2227918 2 + 1677 PE family protein - none - gi|15609120 fig|83332.1.peg.1986 CDS NC_000962 2228559 2227906 -3 - 654 Cutinase precursor Cfp21 (EC 3.1.1.74) - none - gi|15609121 fig|83332.1.peg.1987 CDS NC_000962 2229900 2228989 -3 - 912 HTH-type transcriptional regulator - none - gi|15609122 fig|83332.1.peg.1988 CDS NC_000962 2230009 2230608 1 + 600 Transporter, LysE family - none - gi|15609123 fig|83332.1.peg.1989 CDS NC_000962 2231024 2231452 2 + 429 Chitinase-related protein - none - gi|15609124 fig|83332.1.peg.1990 CDS NC_000962 2231678 2232217 2 + 540 rRNA adenine N-6-methyltransferase (EC 2.1.1.48) - none - gi|15609125 fig|83332.1.peg.1991 CDS NC_000962 2233297 2232737 -1 - 561 hypothetical protein Rv1989c - none - gi|15609126 fig|83332.1.peg.1992 CDS NC_000962 2233635 2233294 -3 - 342 FIG036251: Hypothetical protein - none - gi|15609127 fig|83332.1.peg.1993 CDS NC_000962 2234647 2234303 -1 - 345 Programmed cell death toxin YdcE MazEF toxin-antitoxing (programmed cell death) system;
Phd-Doc, YdcE-YdcD toxin-antitoxin (programmed cell death) systems gi|15609128 fig|83332.1.peg.1994 CDS NC_000962 2237304 2234989 -3 - 2316 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) Copper Transport System;
Copper homeostasis;
Terminal cytochrome C oxidases gi|15609129 fig|83332.1.peg.1995 CDS NC_000962 2237573 2237301 -2 - 273 hypothetical protein - none - gi|15609130 fig|83332.1.peg.1996 CDS NC_000962 2237982 2237626 -3 - 357 Transcriptional regulator, ArsR family cAMP signaling in bacteria gi|15609131 fig|83332.1.peg.1997 CDS NC_000962 2238139 2238906 1 + 768 hypothetical protein - none - gi|15609132 fig|83332.1.peg.1998 CDS NC_000962 2239002 2239955 3 + 954 Universal stress protein family - none - gi|15609133 fig|83332.1.peg.1999 CDS NC_000962 2240157 2242874 3 + 2718 Cation-transporting ATPase, E1-E2 family Magnesium transport gi|15609134 fig|83332.1.peg.2000 CDS NC_000962 2243719 2242943 -1 - 777 PEP phosphonomutase and related enzymes - none - gi|15609135 fig|83332.1.peg.2001 CDS NC_000962 2245136 2243814 -2 - 1323 Uncharacterized transporter Rv1999c/MT2055 - none - gi|15609136 fig|83332.1.peg.2002 CDS NC_000962 2245207 2246820 1 + 1614 FIG029313: hypothetical protein Rv2000/MT2056 - none - gi|15609137 fig|83332.1.peg.2003 CDS NC_000962 2246830 2247582 1 + 753 FIG030323: hypothetical protein Rv2001/MT2057 - none - gi|15609138 fig|83332.1.peg.2004 CDS NC_000962 2247658 2248440 1 + 783 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase (EC 1.1.1.53) - none - gi|15609139 fig|83332.1.peg.2005 CDS NC_000962 2249418 2248561 -3 - 858 FIG147732: hypothetical protein Rv2003c/MT2059 Mycobacterium virulence operon involved with a mostly uncharacterized dormancy regulon gi|15609140 fig|83332.1.peg.2006 CDS NC_000962 2250972 2249476 -3 - 1497 FIG037390: hypothetical protein Rv2004c/MT2060 Mycobacterium virulence operon involved with a mostly uncharacterized dormancy regulon gi|15609141 fig|83332.1.peg.2007 CDS NC_000962 2251881 2250994 -3 - 888 FIG153983: hypothetical protein Rv2005c/MT2061 Mycobacterium virulence operon involved with a mostly uncharacterized dormancy regulon gi|15609142 fig|83332.1.peg.2008 CDS NC_000962 2252000 2255983 2 + 3984 Trehalose-6-phosphate phosphatase (EC 3.1.3.12) Mycobacterium virulence operon involved with a mostly uncharacterized dormancy regulon gi|15609143 fig|83332.1.peg.2009 CDS NC_000962 2256426 2256082 -3 - 345 4Fe-4S ferredoxin, iron-sulfur binding Inorganic Sulfur Assimilation;
Mycobacterium virulence operon involved with a mostly uncharacterized dormancy regulon gi|15609144 fig|83332.1.peg.2010 CDS NC_000962 2257940 2256615 -2 - 1326 AAA family ATPase - none - gi|15609145 fig|83332.1.peg.2011 CDS NC_000962 2258028 2258270 3 + 243 hypothetical protein - none - gi|15609146 fig|83332.1.peg.2012 CDS NC_000962 2258271 2258669 3 + 399 Toxin 1, PIN domain Toxin-Antitoxin MT1 gi|15609147 fig|83332.1.peg.2013 CDS NC_000962 2259283 2258852 -1 - 432 Transcriptional regulator, MarR family - none - gi|15609148 fig|83332.1.peg.2014 CDS NC_000962 2259324 2259818 3 + 495 FIG042535: hypothetical protein, Rv2012/MT2067 - none - gi|15609149 fig|83332.1.peg.2015 CDS NC_000962 2260441 2261142 1 + 702 Mobile element protein - none - gi|15609150 fig|83332.1.peg.2016 CDS NC_000962 2261003 2261668 2 + 666 Mobile element protein - none - gi|15609151 fig|83332.1.peg.2017 CDS NC_000962 2263070 2261814 -2 - 1257 HNH endonuclease domain protein - none - gi|15609152 fig|83332.1.peg.2018 CDS NC_000962 2263424 2263999 2 + 576 hypothetical protein Rv2016 - none - gi|15609153 fig|83332.1.peg.2019 CDS NC_000962 2263996 2265036 1 + 1041 Zn peptidase with DNA binding - none - gi|15609154 fig|83332.1.peg.2020 CDS NC_000962 2265278 2265997 2 + 720 hypothetical protein Rv2018 - none - gi|15609155 fig|83332.1.peg.2021 CDS NC_000962 2265987 2266403 3 + 417 hypothetical protein Rv2019 - none - gi|15609156 fig|83332.1.peg.2022 CDS NC_000962 2266718 2266419 -2 - 300 Putative helicase - none - gi|15609157 fig|83332.1.peg.2023 CDS NC_000962 2267108 2266803 -2 - 306 Transcriptional regulator, XRE family - none - gi|15609158 fig|83332.1.peg.2024 CDS NC_000962 2267722 2267117 -1 - 606 hypothetical protein Rv2022c - none - gi|15609159 fig|83332.1.peg.2025 CDS NC_000962 2268106 2267747 -1 - 360 hypothetical protein Rv2023c - none - gi|15609160 fig|83332.1.peg.2026 CDS NC_000962 2270238 2268691 -3 - 1548 Helicase - none - gi|15609161 fig|83332.1.peg.2027 CDS NC_000962 2271746 2270748 -2 - 999 Cobalt-zinc-cadmium resistance protein - none - gi|15609162 fig|83332.1.peg.2028 CDS NC_000962 2272745 2271861 -2 - 885 Universal stress protein family Universal stress protein family gi|15609163 fig|83332.1.peg.2029 CDS NC_000962 2274506 2272785 -2 - 1722 Histidine kinase response regulator - none - gi|15609164 fig|83332.1.peg.2030 CDS NC_000962 2275406 2274567 -2 - 840 Universal stress protein family Mycobacterium virulence operon involved with a dormancy regulon;
Universal stress protein family gi|15609165 fig|83332.1.peg.2031 CDS NC_000962 2276422 2275403 -1 - 1020 Tagatose-6-phosphate kinase (EC 2.7.1.144) / 1-phosphofructokinase (EC 2.7.1.56) Lactose and Galactose Uptake and Utilization;
Mycobacterium virulence operon involved with a dormancy regulon gi|15609166 fig|83332.1.peg.2032 CDS NC_000962 2278484 2276439 -2 - 2046 Erythromycin esterase homolog Mycobacterium virulence operon involved with a dormancy regulon gi|15609167 fig|83332.1.peg.2033 CDS NC_000962 2278930 2278496 -1 - 435 14 kDa antigen (16 kDa antigen) (HSP 16.3) Mycobacterium virulence operon involved with a dormancy regulon gi|15609168 fig|83332.1.peg.2034 CDS NC_000962 2279127 2280122 3 + 996 Dinucleotide-utilizing enzyme, Rv2032/acg (acr-coregulated gene) Mycobacterium virulence operon involved with a dormancy regulon gi|15609169 fig|83332.1.peg.2035 CDS NC_000962 2281080 2280238 -3 - 843 hypothetical protein Rv2033c - none - gi|15609170 fig|83332.1.peg.2036 CDS NC_000962 2281292 2281615 2 + 324 Transcriptional regulator, ArsR family - none - gi|15609171 fig|83332.1.peg.2037 CDS NC_000962 2281612 2282100 1 + 489 Putative uncharacterized protein BCG_2054 - none - gi|15609172 fig|83332.1.peg.2038 CDS NC_000962 2282097 2282738 3 + 642 Putative uncharacterized protein BCG_2055 - none - gi|15609173 fig|83332.1.peg.2039 CDS NC_000962 2283719 2282745 -2 - 975 lysophospholipase-like family protein - none - gi|15609174 fig|83332.1.peg.2040 CDS NC_000962 2284794 2283721 -3 - 1074 Probable sugar-transport ATP-binding protein ABC transporter - none - gi|15609175 fig|83332.1.peg.2041 CDS NC_000962 2285639 2284797 -2 - 843 Probable sugar-transport integral membrane protein ABC transporter - none - gi|15609176 fig|83332.1.peg.2042 CDS NC_000962 2286528 2285626 -3 - 903 Probable sugar-transport integral membrane protein ABC transporter - none - gi|15609177 fig|83332.1.peg.2043 CDS NC_000962 2287844 2286525 -2 - 1320 Probable sugar-binding lipoprotein - none - gi|15609178 fig|83332.1.peg.2044 CDS NC_000962 2288679 2287882 -3 - 798 Putative uncharacterized protein BCG_2061c - none - gi|15609179 fig|83332.1.peg.2045 CDS NC_000962 2289239 2288679 -2 - 561 Nicotinamidase (EC 3.5.1.19) NAD and NADP cofactor biosynthesis global;
Redox-dependent regulation of nucleus processes;
cAMP signaling in bacteria gi|15609180 fig|83332.1.peg.2046 CDS NC_000962 2289597 2289280 -3 - 318 Possible membrane protein - none - gi|15609181 fig|83332.1.peg.2047 CDS NC_000962 2291218 2289683 -1 - 1536 Probable carboxylesterase LipT (EC 3.1.1.-) - none - gi|15609182 fig|83332.1.peg.2048 CDS NC_000962 2291267 2291923 2 + 657 Probable lipoprotein lppI - none - gi|15609183 fig|83332.1.peg.2049 CDS NC_000962 2294524 2291960 -1 - 2565 Phosphoenolpyruvate synthase (EC 2.7.9.2) Glycolysis and Gluconeogenesis;
Inteins;
Pyruvate metabolism I: anaplerotic reactions, PEP gi|15609184 fig|83332.1.peg.2050 CDS NC_000962 2306984 2294529 -2 - 12456 Polyketide synthase - none - gi|15609185 fig|83332.1.peg.2051 CDS NC_000962 2307515 2307291 -2 - 225 hypothetical protein - none - gi|15609186 fig|83332.1.peg.2052 CDS NC_000962 2307819 2308154 3 + 336 FIG00820327: hypothetical protein Lipid-linked oligosaccharide synthesis related cluster gi|15609187 fig|83332.1.peg.2053 CDS NC_000962 2310753 2308129 -3 - 2625 Apolipoprotein N-acyltransferase (EC 2.3.1.-) in lipid-linked oligosaccharide synthesis cluster / Dolichol-phosphate mannosyltransferase (EC 2.4.1.83) in lipid-linked oligosaccharide synthesis cluster Lipid-linked oligosaccharide synthesis related cluster;
Lipid-linked oligosaccharide synthesis related cluster gi|15609188 fig|83332.1.peg.2054 CDS NC_000962 2312515 2310911 -1 - 1605 Exoenzymes regulatory protein AepA in lipid-linked oligosaccharide synthesis cluster Lipid-linked oligosaccharide synthesis related cluster gi|15609189 fig|83332.1.peg.2055 CDS NC_000962 2313047 2312520 -2 - 528 Cytoplasmic membrane protein FsxA Lipid-linked oligosaccharide synthesis related cluster gi|15609190 fig|83332.1.peg.2056 CDS NC_000962 2313123 2313836 3 + 714 Dienelactone hydrolase family protein - none - gi|15609191 fig|83332.1.peg.2057 CDS NC_000962 2314351 2314085 -1 - 267 SSU ribosomal protein S18p @ SSU ribosomal protein S18p, zinc-independent Ribosome SSU bacterial;
Ribosome SSU bacterial gi|15609192 fig|83332.1.peg.2058 CDS NC_000962 2314657 2314352 -1 - 306 SSU ribosomal protein S14p (S29e) @ SSU ribosomal protein S14p (S29e), zinc-independent Ribosome SSU bacterial;
Ribosome SSU bacterial gi|15609193 fig|83332.1.peg.2059 CDS NC_000962 2314823 2314659 -2 - 165 LSU ribosomal protein L33p @ LSU ribosomal protein L33p, zinc-independent Ribosome LSU bacterial;
Ribosome LSU bacterial gi|15609194 fig|83332.1.peg.2060 CDS NC_000962 2315059 2314823 -1 - 237 LSU ribosomal protein L28p Ribosome LSU bacterial gi|15609195 fig|83332.1.peg.2061 CDS NC_000962 2315172 2316707 3 + 1536 Zinc ABC transporter, periplasmic-binding protein ZnuA - none - gi|15609196 fig|83332.1.peg.2062 CDS NC_000962 2316277 2316678 1 + 402 hypothetical protein Rv2060 - none - gi|15609197 fig|83332.1.peg.2063 CDS NC_000962 2317083 2316679 -3 - 405 hypothetical protein - none - gi|15609198 fig|83332.1.peg.2064 CDS NC_000962 2320751 2317167 -2 - 3585 CobN component of cobalt chelatase involved in B12 biosynthesis Coenzyme B12 biosynthesis gi|15609199 fig|83332.1.peg.2065 CDS NC_000962 2321224 2320856 -1 - 369 hypothetical protein Rv2063c - none - gi|15609200 fig|83332.1.peg.2066 CDS NC_000962 2321449 2322540 1 + 1092 Cobalamin biosynthesis protein CobG Coenzyme B12 biosynthesis gi|15609201 fig|83332.1.peg.2067 CDS NC_000962 2322550 2323176 1 + 627 Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) Cobalamin synthesis;
Coenzyme B12 biosynthesis gi|15609202 fig|83332.1.peg.2068 CDS NC_000962 2323173 2324699 3 + 1527 Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) / Cobalt-precorrin-3b C17-methyltransferase Cobalamin synthesis;
Cobalamin synthesis;
Coenzyme B12 biosynthesis;
Coenzyme B12 biosynthesis gi|15609203 fig|83332.1.peg.2069 CDS NC_000962 2325868 2324645 -1 - 1224 3-demethylubiquinone-9 3-methyltransferase (EC 2.1.1.64) - none - gi|15609204 fig|83332.1.peg.2070 CDS NC_000962 2326807 2325884 -1 - 924 Beta-lactamase class A Beta-lactamase gi|15609205 fig|83332.1.peg.2071 CDS NC_000962 2326942 2327499 1 + 558 RNA polymerase sigma-54 factor RpoN - none - gi|15609206 fig|83332.1.peg.2072 CDS NC_000962 2328223 2327489 -1 - 735 Cobalt-precorrin-6x reductase (EC 1.3.1.54) Cobalamin synthesis;
Coenzyme B12 biosynthesis gi|15609207 fig|83332.1.peg.2073 CDS NC_000962 2328975 2328220 -3 - 756 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) Cobalamin synthesis;
Coenzyme B12 biosynthesis gi|15609208 fig|83332.1.peg.2074 CDS NC_000962 2330144 2328972 -2 - 1173 Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) Coenzyme B12 biosynthesis;
Coenzyme B12 biosynthesis gi|15609209 fig|83332.1.peg.2075 CDS NC_000962 2330961 2330212 -3 - 750 Oxidoreductase, short-chain dehydrogenase/reductase family - none - gi|15609210 fig|83332.1.peg.2076 CDS NC_000962 2330991 2331404 3 + 414 hypothetical protein Rv2074 - none - gi|15609211 fig|83332.1.peg.2077 CDS NC_000962 2332877 2331414 -2 - 1464 hypothetical protein Rv2075c - none - gi|15609212 fig|83332.1.peg.2078 CDS NC_000962 2333286 2333035 -3 - 252 hypothetical protein Rv2076c - none - gi|15609213 fig|83332.1.peg.2079 CDS NC_000962 2334292 2333321 -1 - 972 Possible membrane protein - none - gi|15609214 fig|83332.1.peg.2080 CDS NC_000962 2335057 2335371 1 + 315 hypothetical protein Rv2078 - none - gi|15609215 fig|83332.1.peg.2081 CDS NC_000962 2335353 2337323 3 + 1971 hypothetical protein Rv2079 - none - gi|15609216 fig|83332.1.peg.2082 CDS NC_000962 2337304 2337867 1 + 564 (MTCY49.19), unknown, len: 187. Possible lipoprotein, contains prokayotic lipoprotein modification site (PS00013) and signal sequence at N-terminus. - none - gi|15609217 fig|83332.1.peg.2083 CDS NC_000962 2338503 2338063 -3 - 441 hypothetical protein Rv2081c - none - gi|15609218 fig|83332.1.peg.2084 CDS NC_000962 2338707 2340872 3 + 2166 FIG031423: hypothetical protein - none - gi|15609219 fig|83332.1.peg.2085 CDS NC_000962 2340869 2341813 2 + 945 hypothetical protein Rv2083 - none - gi|15609220 fig|83332.1.peg.2086 CDS NC_000962 2341806 2342942 3 + 1137 hypothetical protein Rv2084 - none - gi|15609221 fig|83332.1.peg.2087 CDS NC_000962 2343025 2343330 1 + 306 hypothetical protein Rv2085 - none - gi|15609222 fig|83332.1.peg.2088 CDS NC_000962 2343261 2343914 3 + 654 hypothetical protein Rv2086 - none - gi|15609223 fig|83332.1.peg.2089 CDS NC_000962 2343857 2344222 2 + 366 hypothetical protein Rv2087 - none - gi|15609224 fig|83332.1.peg.2090 CDS NC_000962 2344409 2346178 2 + 1770 Serine/threonine protein kinase PknJ (EC 2.7.11.1) - none - gi|15609225 fig|83332.1.peg.2091 CDS NC_000962 2347322 2346195 -2 - 1128 Probable dipeptidase PepE (EC 3.4.13.-) - none - gi|15609226 fig|83332.1.peg.2092 CDS NC_000962 2347371 2348552 3 + 1182 Probable 5'-3' exonuclease Bsu YpcP DNA replication strays gi|15609227 fig|83332.1.peg.2093 CDS NC_000962 2349290 2348556 -2 - 735 Possible membrane protein - none - gi|15609228 fig|83332.1.peg.2094 CDS NC_000962 2352052 2349332 -1 - 2721 FIG005666: putative helicase Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related gi|15609229 fig|83332.1.peg.2095 CDS NC_000962 2353027 2352101 -1 - 927 Twin-arginine translocation protein TatC Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related;
Twin-arginine translocation system gi|15609230 fig|83332.1.peg.2096 CDS NC_000962 2353295 2353044 -2 - 252 Twin-arginine translocation protein TatA Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related;
Twin-arginine translocation system gi|15609231 fig|83332.1.peg.2097 CDS NC_000962 2354313 2353363 -3 - 951 FIG019733: possible DNA-binding protein Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related gi|15609232 fig|83332.1.peg.2098 CDS NC_000962 2355308 2354310 -2 - 999 FIG005453: Putative DeoR-family transcriptional regulator Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related gi|15609233 fig|83332.1.peg.2099 CDS NC_000962 2356675 2355317 -1 - 1359 Pup ligase PafA, possible component of postulated heterodimer PafA-PafA' Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related;
Proteasome archaeal gi|15609234 fig|83332.1.peg.2100 CDS NC_000962 2358031 2356727 -1 - 1305 FIG033545: PE-PGRS family protein Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related gi|15609235 fig|83332.1.peg.2101 CDS NC_000962 2358204 2358031 -3 - 174 (MTCY49.39c), len: 58. 5'-end of MTCY49.38c, then frameshifts. Sequence has been checked, no errors found - none - gi|15609236 fig|83332.1.peg.2102 CDS NC_000962 2358387 2360039 3 + 1653 FIG034520: hypothetical protein - none - gi|15609237 fig|83332.1.peg.2103 CDS NC_000962 2360238 2363279 3 + 3042 Helicase, SNF2/RAD54 family - none - gi|15609238 fig|83332.1.peg.2104 CDS NC_000962 2363389 2364105 1 + 717 FIG006557: hypothetical protein - none - gi|15609239 fig|83332.1.peg.2105 CDS NC_000962 2364518 2364084 -2 - 435 Toxin 1, PIN domain Toxin-Antitoxin MT1 gi|15609240 fig|83332.1.peg.2106 CDS NC_000962 2364779 2364525 -2 - 255 hypothetical protein Rv2104c - none - gi|15609241 fig|83332.1.peg.2107 CDS NC_000962 2365463 2365789 2 + 327 Mobile element protein - none - gi|15609242 fig|83332.1.peg.2108 CDS NC_000962 2365786 2366724 1 + 939 Mobile element protein - none - gi|15609243 fig|83332.1.peg.2109 CDS NC_000962 2367357 2367653 3 + 297 PE family protein - none - gi|15609244 fig|83332.1.peg.2110 CDS NC_000962 2367709 2368440 1 + 732 PPE family protein CBSS-164757.7.peg.5020 gi|15609245 fig|83332.1.peg.2111 CDS NC_000962 2369727 2368981 -3 - 747 Proteasome subunit alpha (EC 3.4.25.1), bacterial Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related;
Proteasome archaeal gi|15609246 fig|83332.1.peg.2112 CDS NC_000962 2370599 2369724 -2 - 876 Proteasome subunit beta (EC 3.4.25.1), bacterial Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related;
Proteasome archaeal gi|15609247 fig|83332.1.peg.2113 CDS NC_000962 2370790 2370596 -1 - 195 Prokaryotic ubiquitin-like protein Pup Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related;
Proteasome archaeal gi|15609248 fig|83332.1.peg.2114 CDS NC_000962 2372567 2370903 -2 - 1665 Pup ligase PafA' paralog, possible component of postulated heterodimer PafA-PafA' Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related;
Proteasome archaeal gi|15609249 fig|83332.1.peg.2115 CDS NC_000962 2372628 2373821 3 + 1194 Possible membrane protein - none - gi|15609250 fig|83332.1.peg.2116 CDS NC_000962 2373832 2374455 1 + 624 hypothetical protein Rv2114 - none - gi|15609251 fig|83332.1.peg.2117 CDS NC_000962 2376288 2374459 -3 - 1830 Bacterial proteasome-activating AAA-ATPase (PAN) Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related;
Proteasome archaeal gi|15609252 fig|83332.1.peg.2118 CDS NC_000962 2376569 2377138 2 + 570 Probable conserved lipoprotein lppK - none - gi|15609253 fig|83332.1.peg.2119 CDS NC_000962 2377146 2377439 3 + 294 YlxP-like protein CBSS-350688.3.peg.1509;
NusA-TFII Cluster gi|15609254 fig|83332.1.peg.2120 CDS NC_000962 2378310 2377468 -3 - 843 RNA methyltransferase - none - gi|15609255 fig|83332.1.peg.2121 CDS NC_000962 2378384 2379220 2 + 837 RecB family exonuclease - none - gi|15609256 fig|83332.1.peg.2122 CDS NC_000962 2379725 2379243 -2 - 483 Hypothetical membrane protein Rv2120c - none - gi|15609257 fig|83332.1.peg.2123 CDS NC_000962 2380658 2379804 -2 - 855 ATP phosphoribosyltransferase (EC 2.4.2.17) Histidine Biosynthesis;
Riboflavin synthesis cluster gi|15609258 fig|83332.1.peg.2124 CDS NC_000962 2380942 2380661 -1 - 282 Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) Histidine Biosynthesis;
Riboflavin synthesis cluster gi|15609259 fig|83332.1.peg.2125 CDS NC_000962 2381069 2382490 2 + 1422 PPE family protein - none - gi|15609260 fig|83332.1.peg.2126 CDS NC_000962 2386065 2382487 -3 - 3579 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) Methionine Biosynthesis gi|15609261 fig|83332.1.peg.2127 CDS NC_000962 2386291 2387169 1 + 879 hypothetical protein Rv2125 - none - gi|15609262 fig|83332.1.peg.2128 CDS NC_000962 2387970 2387200 -3 - 771 (MTCY261.22c), len: 256 aa. Possible PE_PGRS pseudogene fragment, similar to the Gly-rich C-terminus of many members of the M. tuberculosis PGRS family eg. MTCY441.04c (778 aa), fasta scores; opt: 935 z-score: 418.8 E(): 4.4e-18, 56.1% identity in 271 aa overlap - none - gi|15609263 fig|83332.1.peg.2129 CDS NC_000962 2388614 2390083 2 + 1470 L-asparagine permease - none - gi|15609264 fig|83332.1.peg.2130 CDS NC_000962 2390083 2390286 1 + 204 Possible membrane protein - none - gi|15609265 fig|83332.1.peg.2131 CDS NC_000962 2391187 2390306 -1 - 882 Oxidoreductase, short-chain dehydrogenase/reductase family - none - gi|15609266 fig|83332.1.peg.2132 CDS NC_000962 2392457 2391213 -2 - 1245 L-cysteine:1D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase MshC Glutathione analogs: mycothiol;
tRNA aminoacylation, Cys gi|15609267 fig|83332.1.peg.2133 CDS NC_000962 2393318 2392515 -2 - 804 Protein cysQ homolog - none - gi|15609268 fig|83332.1.peg.2134 CDS NC_000962 2393409 2393639 3 + 231 DNA-binding protein, CopG family - none - gi|15609269 fig|83332.1.peg.2135 CDS NC_000962 2394637 2393849 -1 - 789 Phosphatidylinositol 3-and 4-kinase family protein - none - gi|15609270 fig|83332.1.peg.2136 CDS NC_000962 2395235 2394648 -2 - 588 FIG00820819: hypothetical protein - none - gi|15609271 fig|83332.1.peg.2137 CDS NC_000962 2396009 2395299 -2 - 711 Phosphoglycerate mutase family Phosphoglycerate mutase protein family gi|15609272 fig|83332.1.peg.2138 CDS NC_000962 2396836 2396006 -1 - 831 Undecaprenyl-diphosphatase (EC 3.6.1.27) - none - gi|15609273 fig|83332.1.peg.2139 CDS NC_000962 2397313 2396900 -1 - 414 FIG00821698: hypothetical protein - none - gi|15609274 fig|83332.1.peg.2140 CDS NC_000962 2397328 2398404 1 + 1077 Lipoprotein LppL - none - gi|15609275 fig|83332.1.peg.2141 CDS NC_000962 2398718 2399791 2 + 1074 Dihydroorotate dehydrogenase (EC 1.3.3.1) De Novo Pyrimidine Synthesis gi|15609276 fig|83332.1.peg.2142 CDS NC_000962 2400326 2399796 -2 - 531 FIG005409: Phospholipid-binding protein - none - gi|15609277 fig|83332.1.peg.2143 CDS NC_000962 2401720 2400374 -1 - 1347 FIG016551: Putative peptidase - none - gi|15609278 fig|83332.1.peg.2144 CDS NC_000962 2402508 2402191 -3 - 318 hypothetical protein - none - gi|15609279 fig|83332.1.peg.2145 CDS NC_000962 2402975 2404033 2 + 1059 Phosphoribosyl transferase domain protein - none - gi|15609280 fig|83332.1.peg.2146 CDS NC_000962 2404519 2404163 -1 - 357 FIG035962: transmembrane protein Cell division cluster gi|15609281 fig|83332.1.peg.2147 CDS NC_000962 2405396 2404614 -2 - 783 FIG055075: Possibly a cell division protein, antigen 84 in Mycobacteria Cell division cluster gi|15609282 fig|83332.1.peg.2148 CDS NC_000962 2405954 2405664 -2 - 291 FIG021764: Possible membrane protein Cell division cluster gi|15609283 fig|83332.1.peg.2149 CDS NC_000962 2406841 2406116 -1 - 726 FIG021292: hypothetical protein Cell division cluster gi|15609284 fig|83332.1.peg.2150 CDS NC_000962 2407614 2406838 -3 - 777 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC A Hypothetical Protein Related to Proline Metabolism;
Cell division cluster gi|15609285 fig|83332.1.peg.2151 CDS NC_000962 2408372 2407620 -2 - 753 COG1496: Uncharacterized conserved protein Cell division cluster;
tRNA modification Bacteria gi|15609286 fig|83332.1.peg.2152 CDS NC_000962 2409522 2408383 -3 - 1140 Cell division protein FtsZ (EC 3.4.24.-) Bacterial Cell Division;
Bacterial Cytoskeleton;
Cell division cluster gi|15609287 fig|83332.1.peg.2153 CDS NC_000962 2410639 2409695 -1 - 945 Cell division protein FtsQ Bacterial Cell Division;
Bacterial Cytoskeleton;
Cell division cluster gi|15609288 fig|83332.1.peg.2154 CDS NC_000962 2412120 2410636 -3 - 1485 UDP-N-acetylmuramate--alanine ligase (EC 6.3.2.8) Cell division cluster;
Peptidoglycan Biosynthesis;
Peptidoglycan biosynthesis--gjo gi|15609289 fig|83332.1.peg.2155 CDS NC_000962 2413349 2412117 -2 - 1233 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (EC 2.4.1.227) Cell division cluster;
Peptidoglycan Biosynthesis gi|15609290 fig|83332.1.peg.2156 CDS NC_000962 2414920 2413346 -1 - 1575 Cell division protein FtsW Bacterial Cell Division;
Bacterial Cytoskeleton;
Cell division cluster gi|15609291 fig|83332.1.peg.2157 CDS NC_000962 2416392 2414932 -3 - 1461 UDP-N-acetylmuramoylalanine--D-glutamate ligase (EC 6.3.2.9) Cell division cluster;
Peptidoglycan Biosynthesis;
Peptidoglycan biosynthesis--gjo gi|15609292 fig|83332.1.peg.2158 CDS NC_000962 2417473 2416394 -1 - 1080 Phospho-N-acetylmuramoyl-pentapeptide-transferase (EC 2.7.8.13) Cell division cluster;
Peptidoglycan Biosynthesis gi|15609293 fig|83332.1.peg.2159 CDS NC_000962 2419002 2417470 -3 - 1533 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase (EC 6.3.2.10) Cell division cluster;
Peptidoglycan Biosynthesis;
Peptidoglycan biosynthesis--gjo gi|15609294 fig|83332.1.peg.2160 CDS NC_000962 2420606 2418999 -2 - 1608 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase (EC 6.3.2.13) Cell division cluster;
Peptidoglycan Biosynthesis;
Peptidoglycan biosynthesis--gjo gi|15609295 fig|83332.1.peg.2161 CDS NC_000962 2421663 2420629 -3 - 1035 FIG038012: hypothetical protein - none - gi|15609296 fig|83332.1.peg.2162 CDS NC_000962 2422001 2421660 -2 - 342 Transcriptional regulator, TetR family # fragment - none - gi|15609297 fig|83332.1.peg.2163 CDS NC_000962 2423135 2422269 -2 - 867 Probable F420-dependent oxidoreductase family protein - none - gi|15609298 fig|83332.1.peg.2164 CDS NC_000962 2424836 2423238 -2 - 1599 PE family protein - none - gi|15609299 fig|83332.1.peg.2165 CDS NC_000962 2427085 2425046 -1 - 2040 Cell division protein FtsI [Peptidoglycan synthetase] (EC 2.4.1.129) 16S rRNA modification within P site of ribosome;
Bacterial Cell Division;
Bacterial Cytoskeleton;
CBSS-83331.1.peg.3039;
Cell division cluster;
Peptidoglycan Biosynthesis gi|15609300 fig|83332.1.peg.2166 CDS NC_000962 2428236 2427082 -3 - 1155 Cell division protein FtsL / proline rich membrane protein Bacterial Cell Division;
Cell division cluster;
Stationary phase repair cluster gi|15609301 fig|83332.1.peg.2167 CDS NC_000962 2429423 2428233 -2 - 1191 rRNA small subunit methyltransferase H # 16S rRNA m(4) C1402 methyltransferase 16S rRNA modification within P site of ribosome;
Bacterial Cell Division;
Cell division cluster gi|15609302 fig|83332.1.peg.2168 CDS NC_000962 2429856 2429425 -3 - 432 Cell division protein MraZ 16S rRNA modification within P site of ribosome;
Bacterial Cell Division;
Bacterial Cytoskeleton;
Cell division cluster gi|15609303 fig|83332.1.peg.2169 CDS NC_000962 2431197 2430157 -3 - 1041 Mobile element protein - none - gi|15609304 fig|83332.1.peg.2170 CDS NC_000962 2431418 2431092 -2 - 327 Mobile element protein - none - gi|15609305 fig|83332.1.peg.2171 CDS NC_000962 2431967 2431563 -2 - 405 FIG017342: transmembrane protein Cell division cluster gi|15609306 fig|83332.1.peg.2172 CDS NC_000962 2432233 2432853 1 + 621 Gnat family acetyltransferase - none - gi|15609307 fig|83332.1.peg.2173 CDS NC_000962 2432949 2433632 3 + 684 Lipoprotein LppM - none - gi|15609308 fig|83332.1.peg.2174 CDS NC_000962 2434534 2433629 -1 - 906 hypothetical protein - none - gi|15609309 fig|83332.1.peg.2175 CDS NC_000962 2434845 2435903 3 + 1059 Geranylgeranyl diphosphate synthase (EC 2.5.1.29) Carotenoids;
Isoprenoid Biosynthesis: Interconversions;
Isoprenoinds for Quinones;
Polyprenyl Diphosphate Biosynthesis gi|15609310 fig|83332.1.peg.2176 CDS NC_000962 2435907 2437457 3 + 1551 Carotene biosynthesis associated membrane protein - none - gi|15609311 fig|83332.1.peg.2177 CDS NC_000962 2437884 2437444 -3 - 441 Conserved hypothetical regulatory protein - none - gi|15609312 fig|83332.1.peg.2178 CDS NC_000962 2437939 2439138 1 + 1200 Serine/threonine protein kinase PknL (EC 2.7.11.1) - none - gi|15609313 fig|83332.1.peg.2179 CDS NC_000962 2439945 2439280 -3 - 666 Mobile element protein - none - gi|15609314 fig|83332.1.peg.2180 CDS NC_000962 2441718 2440330 -3 - 1389 2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphate synthase II (EC 2.5.1.54) # AroA II Chorismate Synthesis;
Common Pathway For Synthesis of Aromatic Compounds (DAHP synthase to chorismate) gi|15609315 fig|83332.1.peg.2181 CDS NC_000962 2442315 2441809 -3 - 507 hypothetical protein Rv2179c - none - gi|15609316 fig|83332.1.peg.2182 CDS NC_000962 2443212 2442325 -3 - 888 Possible membrane protein - none - gi|15609317 fig|83332.1.peg.2183 CDS NC_000962 2443300 2444583 1 + 1284 Possible membrane protein - none - gi|15609318 fig|83332.1.peg.2184 CDS NC_000962 2445327 2444584 -3 - 744 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51) Glycerolipid and Glycerophospholipid Metabolism in Bacteria;
Phosphate metabolism;
Ribosome post-transcriptional modification and chromosomal segregation cluster gi|15609319 fig|83332.1.peg.2185 CDS NC_000962 2445808 2445413 -1 - 396 hypothetical protein Rv2183c - none - gi|15609320 fig|83332.1.peg.2186 CDS NC_000962 2446944 2445805 -3 - 1140 Arsenical pump-driving ATPase (EC 3.6.3.16) Arsenic resistance gi|15609321 fig|83332.1.peg.2187 CDS NC_000962 2447498 2447064 -2 - 435 hypothetical protein Rv2185c - none - gi|15609322 fig|83332.1.peg.2188 CDS NC_000962 2447992 2447603 -1 - 390 hypothetical protein Rv2186c - none - gi|15609323 fig|83332.1.peg.2189 CDS NC_000962 2448158 2449960 2 + 1803 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) Biotin biosynthesis;
Biotin synthesis cluster;
Fatty acid metabolism cluster gi|15609324 fig|83332.1.peg.2190 CDS NC_000962 2451190 2449991 -1 - 1200 Poly(glycerol-phosphate) alpha-glucosyltransferase (EC 2.4.1.52) - none - gi|15609325 fig|83332.1.peg.2191 CDS NC_000962 2452018 2451245 -1 - 774 hypothetical protein Rv2189c - none - gi|15609326 fig|83332.1.peg.2192 CDS NC_000962 2453270 2452113 -2 - 1158 Probable endopeptidase - none - gi|15609327 fig|83332.1.peg.2193 CDS NC_000962 2453817 2455754 3 + 1938 DNA polymerase III epsilon subunit-related protein MSMEG4261 - none - gi|15609328 fig|83332.1.peg.2194 CDS NC_000962 2456741 2455629 -2 - 1113 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) Chorismate: Intermediate for synthesis of Tryptophan, PAPA antibiotics, PABA, 3-hydroxyanthranilate and more.;
Tryptophan synthesis gi|15609329 fig|83332.1.peg.2195 CDS NC_000962 2456899 2457510 1 + 612 Cytochrome c oxidase polypeptide III (EC 1.9.3.1) CBSS-316057.3.peg.563;
Terminal cytochrome C oxidases gi|15609330 fig|83332.1.peg.2196 CDS NC_000962 2457551 2458393 2 + 843 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit Ubiquinone Menaquinone-cytochrome c reductase complexes gi|15609331 fig|83332.1.peg.2197 CDS NC_000962 2458390 2459679 1 + 1290 Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) Ubiquinone Menaquinone-cytochrome c reductase complexes gi|15609332 fig|83332.1.peg.2198 CDS NC_000962 2459676 2461325 3 + 1650 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) Ubiquinone Menaquinone-cytochrome c reductase complexes gi|15609333 fig|83332.1.peg.2199 CDS NC_000962 2462146 2461502 -1 - 645 Possible membrane protein - none - gi|15609334 fig|83332.1.peg.2200 CDS NC_000962 2463045 2462146 -3 - 900 Putative membrane protein MmpS3 - none - gi|15609335 fig|83332.1.peg.2201 CDS NC_000962 2463650 2463231 -2 - 420 Probable cytochrome c oxidase polypeptide 4 (EC 1.9.3.1) - none - gi|15609336 fig|83332.1.peg.2202 CDS NC_000962 2464749 2463658 -3 - 1092 Cytochrome c oxidase polypeptide II (EC 1.9.3.1) CBSS-316057.3.peg.563;
Terminal cytochrome C oxidases gi|15609337 fig|83332.1.peg.2203 CDS NC_000962 2464995 2466953 3 + 1959 Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) Glutamine, Glutamate, Aspartate and Asparagine Biosynthesis gi|15609338 fig|83332.1.peg.2204 CDS NC_000962 2468025 2467051 -3 - 975 Adenosine kinase (EC 2.7.1.20) Purine conversions gi|15609339 fig|83332.1.peg.2205 CDS NC_000962 2468229 2468921 3 + 693 Possible membrane protein - none - gi|15609340 fig|83332.1.peg.2206 CDS NC_000962 2469285 2468929 -3 - 357 probable iron binding protein from the HesB_IscA_SufA family - none - gi|15609341 fig|83332.1.peg.2207 CDS NC_000962 2470827 2469385 -3 - 1443 Glycerate kinase (EC 2.7.1.31) Glycerate metabolism;
Glycerolipid and Glycerophospholipid Metabolism in Bacteria;
Glycine and Serine Utilization;
Serine-glyoxylate cycle gi|15609342 fig|83332.1.peg.2208 CDS NC_000962 2470956 2471330 3 + 375 CblZ, a non-orthologous displasment for Alpha-ribazole-5'-phosphate phosphatase Coenzyme B12 biosynthesis gi|15609343 fig|83332.1.peg.2209 CDS NC_000962 2471409 2472494 3 + 1086 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) Cobalamin synthesis;
Coenzyme B12 biosynthesis;
Heme and Siroheme Biosynthesis gi|15609344 fig|83332.1.peg.2210 CDS NC_000962 2472491 2473240 2 + 750 Cobalamin synthase (EC 2.7.8.26) Cobalamin synthesis;
Coenzyme B12 biosynthesis;
Heme and Siroheme Biosynthesis gi|15609345 fig|83332.1.peg.2211 CDS NC_000962 2473398 2474936 3 + 1539 hypothetical protein Rv2209 - none - gi|15609346 fig|83332.1.peg.2212 CDS NC_000962 2475968 2474862 -2 - 1107 Branched-chain amino acid aminotransferase (EC 2.6.1.42) Alanine biosynthesis;
Branched-Chain Amino Acid Biosynthesis;
Dehydrogenase complexes;
Isoleucine degradation;
Leucine Biosynthesis;
Leucine Degradation and HMG-CoA Metabolism;
Pyruvate Alanine Serine Interconversions;
Valine degradation gi|15609347 fig|83332.1.peg.2213 CDS NC_000962 2477179 2476040 -1 - 1140 Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10) Glycine and Serine Utilization;
Glycine cleavage system gi|15609348 fig|83332.1.peg.2214 CDS NC_000962 2477188 2478324 1 + 1137 Adenylate cyclase (EC 4.6.1.1) cAMP signaling in bacteria gi|15609349 fig|83332.1.peg.2215 CDS NC_000962 2478336 2479883 3 + 1548 Cytosol aminopeptidase PepA (EC 3.4.11.1) Aminopeptidases (EC 3.4.11.-);
Dehydrogenase complexes gi|15609350 fig|83332.1.peg.2216 CDS NC_000962 2481699 2479921 -3 - 1779 Oxidoreductase, short-chain dehydrogenase/reductase family (EC 1.1.1.-) - none - gi|15609351 fig|83332.1.peg.2217 CDS NC_000962 2481963 2483624 3 + 1662 Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168) Dehydrogenase complexes;
Isoleucine degradation;
Leucine Degradation and HMG-CoA Metabolism;
Lipoic acid metabolism;
Valine degradation gi|15609352 fig|83332.1.peg.2218 CDS NC_000962 2483624 2484529 2 + 906 Cell division inhibitor Persister Cells gi|15609353 fig|83332.1.peg.2219 CDS NC_000962 2484582 2485274 3 + 693 Octanoate-[acyl-carrier-protein]-protein-N-octanoyltransferase Dehydrogenase complexes;
Lipoic acid metabolism;
Lipoic acid synthesis cluster gi|15609354 fig|83332.1.peg.2220 CDS NC_000962 2485271 2486206 2 + 936 Lipoate synthase Lipoic acid metabolism;
Lipoic acid synthesis cluster gi|15609355 fig|83332.1.peg.2221 CDS NC_000962 2486233 2486985 1 + 753 Transmembrane protein MT2276, clustered with lipoate gene Lipoic acid metabolism gi|15609356 fig|83332.1.peg.2222 CDS NC_000962 2487613 2489049 1 + 1437 Glutamine synthetase type I (EC 6.3.1.2) Ammonia assimilation;
Glutamine, Glutamate, Aspartate and Asparagine Biosynthesis;
Glutamine synthetases;
Peptidoglycan Biosynthesis gi|15609357 fig|83332.1.peg.2223 CDS NC_000962 2492351 2489367 -2 - 2985 Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42) Ammonia assimilation gi|15609358 fig|83332.1.peg.2224 CDS NC_000962 2493740 2492400 -2 - 1341 Glutamine synthetase type I (EC 6.3.1.2) Ammonia assimilation;
Glutamine, Glutamate, Aspartate and Asparagine Biosynthesis;
Glutamine synthetases;
Peptidoglycan Biosynthesis gi|15609359 fig|83332.1.peg.2225 CDS NC_000962 2495397 2493835 -3 - 1563 Putative hydrolase - none - gi|15609360 fig|83332.1.peg.2226 CDS NC_000962 2497021 2495459 -1 - 1563 Probable exported protease [EC:3.4.-.-] - none - gi|15609361 fig|83332.1.peg.2227 CDS NC_000962 2497740 2498585 3 + 846 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) Coenzyme A Biosynthesis;
Coenzyme A Biosynthesis cluster gi|15609362 fig|83332.1.peg.2228 CDS NC_000962 2498830 2500371 1 + 1542 CHAD domain containing protein - none - gi|15609363 fig|83332.1.peg.2229 CDS NC_000962 2500929 2501630 3 + 702 hypothetical protein Rv2227 - none - gi|15609364 fig|83332.1.peg.2230 CDS NC_000962 2502736 2501642 -1 - 1095 FIG006762: Phosphoglycerate mutase family CBSS-100226.1.peg.2266 gi|15609365 fig|83332.1.peg.2231 CDS NC_000962 2503470 2502733 -3 - 738 FIG137478: Hypothetical protein CBSS-100226.1.peg.2266;
tRNA modification Bacteria gi|15609366 fig|83332.1.peg.2232 CDS NC_000962 2504606 2503467 -2 - 1140 FIG042796: Hypothetical protein CBSS-100226.1.peg.2266 gi|15609367 fig|83332.1.peg.2233 CDS NC_000962 2505697 2504603 -1 - 1095 L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) Cobalamin synthesis;
Coenzyme B12 biosynthesis gi|15609368 fig|83332.1.peg.2234 CDS NC_000962 2506276 2506743 1 + 468 Phosphoglycolate phosphatase (EC 3.1.3.18) 2-phosphoglycolate salvage gi|15609369 fig|83332.1.peg.2235 CDS NC_000962 2506744 2507151 1 + 408 Phosphoglycolate phosphatase (EC 3.1.3.18) 2-phosphoglycolate salvage gi|15609370 fig|83332.1.peg.2236 CDS NC_000962 2507144 2507635 2 + 492 Low molecular weight protein tyrosine phosphatase (EC 3.1.3.48) - none - gi|15609371 fig|83332.1.peg.2237 CDS NC_000962 2507635 2508450 1 + 816 Cytochrome oxidase biogenesis protein Surf1, facilitates heme A insertion Biogenesis of cytochrome c oxidases;
CBSS-316057.3.peg.563 gi|15609372 fig|83332.1.peg.2238 CDS NC_000962 2509373 2508432 -2 - 942 Adenosylcobinamide-phosphate synthase (EC 6.3.1.10) Cobalamin synthesis;
Coenzyme B12 biosynthesis gi|15609373 fig|83332.1.peg.2239 CDS NC_000962 2509487 2510254 2 + 768 hypothetical protein Rv2237 - none - gi|15609374 fig|83332.1.peg.2240 CDS NC_000962 2511174 2510713 -3 - 462 2-cys peroxiredoxin BAS1, chloroplast precursor - none - gi|15609375 fig|83332.1.peg.2241 CDS NC_000962 2511650 2511174 -2 - 477 hypothetical protein Rv2239c - none - gi|15609376 fig|83332.1.peg.2242 CDS NC_000962 2512485 2511688 -3 - 798 hypothetical protein - none - gi|15609377 fig|83332.1.peg.2243 CDS NC_000962 2512537 2515242 1 + 2706 Pyruvate dehydrogenase E1 component (EC 1.2.4.1) 5-FCL-like protein;
Dehydrogenase complexes;
Methionine Degradation;
Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate gi|15609378 fig|83332.1.peg.2244 CDS NC_000962 2515302 2516546 3 + 1245 Hypothetical protein, possibly related to signal transduction - none - gi|15609379 fig|83332.1.peg.2245 CDS NC_000962 2516785 2517693 1 + 909 Malonyl CoA-acyl carrier protein transacylase (EC 2.3.1.39) Fatty Acid Biosynthesis FASII gi|15609380 fig|83332.1.peg.2246 CDS NC_000962 2517769 2518116 1 + 348 Acyl carrier protein Fatty Acid Biosynthesis FASII;
Glycerolipid and Glycerophospholipid Metabolism in Bacteria gi|15609381 fig|83332.1.peg.2247 CDS NC_000962 2518113 2519363 3 + 1251 3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.179) Fatty Acid Biosynthesis FASII;
Mycobacterium virulence operon involved in fatty acids biosynthesis gi|15609382 fig|83332.1.peg.2248 CDS NC_000962 2519394 2520710 3 + 1317 3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.41) Fatty Acid Biosynthesis FASII;
Mycobacterium virulence operon involved in fatty acids biosynthesis gi|15609383 fig|83332.1.peg.2249 CDS NC_000962 2520741 2522162 3 + 1422 Propionyl-CoA carboxylase beta chain (EC 6.4.1.3) CBSS-83332.1.peg.3803;
Mycobacterium virulence operon involved in fatty acids biosynthesis;
Serine-glyoxylate cycle gi|15609384 fig|83332.1.peg.2250 CDS NC_000962 2522358 2523173 3 + 816 hypothetical protein Rv2248 - none - gi|15609385 fig|83332.1.peg.2251 CDS NC_000962 2524789 2523239 -1 - 1551 Glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) Glycerol and Glycerol-3-phosphate Uptake and Utilization;
Glycerolipid and Glycerophospholipid Metabolism in Bacteria;
Respiratory dehydrogenases 1 gi|15609386 fig|83332.1.peg.2252 CDS NC_000962 2525442 2524783 -3 - 660 Transcriptional regulator, TetR family - none - gi|15609387 fig|83332.1.peg.2253 CDS NC_000962 2525563 2526990 1 + 1428 Flavoprotein - none - gi|15609388 fig|83332.1.peg.2254 CDS NC_000962 2526987 2527916 3 + 930 Diacylglycerol kinase-related protein - none - gi|15609389 fig|83332.1.peg.2255 CDS NC_000962 2527982 2528485 2 + 504 FIG00820044: hypothetical protein - none - gi|15609390 fig|83332.1.peg.2256 CDS NC_000962 2528973 2528518 -3 - 456 Possible membrane protein - none - gi|15609391 fig|83332.1.peg.2257 CDS NC_000962 2529172 2528978 -1 - 195 FIG099973: hypothetical protein - none - gi|15609392 fig|83332.1.peg.2258 CDS NC_000962 2529872 2529339 -2 - 534 hypothetical protein Rv2256c - none - gi|15609393 fig|83332.1.peg.2259 CDS NC_000962 2530820 2530002 -2 - 819 Beta-lactamase class C and other penicillin binding proteins Beta-lactamase gi|15609394 fig|83332.1.peg.2260 CDS NC_000962 2531895 2530834 -3 - 1062 Possible transcriptional regulatory protein - none - gi|15609395 fig|83332.1.peg.2261 CDS NC_000962 2532243 2533328 3 + 1086 Formaldehyde dehydrogenase MscR, NAD/mycothiol-dependent (EC 1.2.1.66) / S-nitrosomycothiol reductase MscR Glutathione analogs: mycothiol;
Glutathione analogs: mycothiol gi|15609396 fig|83332.1.peg.2262 CDS NC_000962 2533328 2533963 2 + 636 Putative hydrolase in cluster with formaldehyde/S-nitrosomycothiol reductase MscR Glutathione analogs: mycothiol gi|15609397 fig|83332.1.peg.2263 CDS NC_000962 2534462 2534040 -2 - 423 Apolipoprotein N-acyltransferase (EC 2.3.1.-) Lipoprotein Biosynthesis;
Phosphate metabolism gi|15609398 fig|83332.1.peg.2264 CDS NC_000962 2535550 2534468 -1 - 1083 Apolipoprotein N-acyltransferase (EC 2.3.1.-) Lipoprotein Biosynthesis;
Phosphate metabolism gi|15609399 fig|83332.1.peg.2265 CDS NC_000962 2535639 2536592 3 + 954 Oxidoreductase, short-chain dehydrogenase/reductase family - none - gi|15609400 fig|83332.1.peg.2266 CDS NC_000962 2538348 2536570 -3 - 1779 Conserved hypothetical proline rich protein - none - gi|15609401 fig|83332.1.peg.2267 CDS NC_000962 2538698 2539927 2 + 1230 FIG00820050: hypothetical protein - none - gi|15609402 fig|83332.1.peg.2268 CDS NC_000962 2540102 2541388 2 + 1287 putative cytochrome P450 hydroxylase - none - gi|15609403 fig|83332.1.peg.2269 CDS NC_000962 2542808 2541642 -2 - 1167 hypothetical protein Rv2267c - none - gi|15609404 fig|83332.1.peg.2270 CDS NC_000962 2544274 2542805 -1 - 1470 Cytochrome P450 128 - none - gi|15609405 fig|83332.1.peg.2271 CDS NC_000962 2544619 2544287 -1 - 333 hypothetical protein Rv2269c - none - gi|15609406 fig|83332.1.peg.2272 CDS NC_000962 2544696 2545223 3 + 528 Lipoprotein LppN - none - gi|15609407 fig|83332.1.peg.2273 CDS NC_000962 2545330 2545629 1 + 300 hypothetical protein - none - gi|15609408 fig|83332.1.peg.2274 CDS NC_000962 2545735 2546103 1 + 369 Possible membrane protein - none - gi|15609409 fig|83332.1.peg.2275 CDS NC_000962 2546100 2546429 3 + 330 Possible membrane protein - none - gi|15609410 fig|83332.1.peg.2276 CDS NC_000962 2546803 2546486 -1 - 318 hypothetical protein Rv2274c - none - gi|15609411 fig|83332.1.peg.2277 CDS NC_000962 2546881 2547750 1 + 870 FIG032699: hypothetical protein - none - gi|15609412 fig|83332.1.peg.2278 CDS NC_000962 2547747 2548937 3 + 1191 Cytochrome P450 121 - none - gi|15609413 fig|83332.1.peg.2279 CDS NC_000962 2550027 2549122 -3 - 906 Glycerophosphoryl diester phosphodiesterase (EC 3.1.4.46) Glycerol and Glycerol-3-phosphate Uptake and Utilization gi|15609414 fig|83332.1.peg.2280 CDS NC_000962 2550063 2550389 3 + 327 Mobile element protein - none - gi|15609415 fig|83332.1.peg.2281 CDS NC_000962 2550386 2551324 2 + 939 Mobile element protein - none - gi|15609416 fig|83332.1.peg.2282 CDS NC_000962 2551558 2552937 1 + 1380 Probable dehydrogenase - none - gi|15609417 fig|83332.1.peg.2283 CDS NC_000962 2553171 2554829 3 + 1659 Probable low-affinity inorganic phosphate transporter Phosphate metabolism gi|15609418 fig|83332.1.peg.2284 CDS NC_000962 2555874 2554936 -3 - 939 hypothetical protein Rv2282c - none - gi|15609419 fig|83332.1.peg.2285 CDS NC_000962 2555939 2556133 2 + 195 hypothetical protein Rv2283 - none - gi|15609420 fig|83332.1.peg.2286 CDS NC_000962 2556143 2557438 2 + 1296 Esterase lipM - none - gi|15609421 fig|83332.1.peg.2287 CDS NC_000962 2557471 2558808 1 + 1338 Diacyglycerol O-acyltransferase (EC 2.3.1.20) - none - gi|15609422 fig|83332.1.peg.2288 CDS NC_000962 2559567 2558875 -3 - 693 hypothetical protein Rv2286c - none - gi|15609423 fig|83332.1.peg.2289 CDS NC_000962 2559701 2561329 2 + 1629 Na+/H+ antiporter - none - gi|15609424 fig|83332.1.peg.2290 CDS NC_000962 2561326 2561703 1 + 378 FIG065022: hypothetical protein - none - gi|15609425 fig|83332.1.peg.2291 CDS NC_000962 2561673 2562455 3 + 783 CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) Glycerolipid and Glycerophospholipid Metabolism in Bacteria gi|15609426 fig|83332.1.peg.2292 CDS NC_000962 2562597 2563112 3 + 516 Lipoprotein LppO - none - gi|15609427 fig|83332.1.peg.2293 CDS NC_000962 2563172 2564026 2 + 855 Thiosulfate sulfurtransferase, rhodanese (EC 2.8.1.1) Single-Rhodanese-domain proteins gi|15609428 fig|83332.1.peg.2294 CDS NC_000962 2564251 2564027 -1 - 225 hypothetical protein Rv2292c - none - gi|15609429 fig|83332.1.peg.2295 CDS NC_000962 2565030 2564290 -3 - 741 hypothetical protein Rv2293c - none - gi|15609430 fig|83332.1.peg.2296 CDS NC_000962 2565325 2566548 1 + 1224 Putative cystathionine beta-lyase (EC 4.4.1.8) - none - gi|15609431 fig|83332.1.peg.2297 CDS NC_000962 2566770 2567408 3 + 639 Colicin E2 tolerance protein CbrC-like protein Tolerance to colicin E2 gi|15609432 fig|83332.1.peg.2298 CDS NC_000962 2567502 2568404 3 + 903 Haloalkane dehalogenase (EC 3.8.1.5) - none - gi|15609433 fig|83332.1.peg.2299 CDS NC_000962 2568436 2568888 1 + 453 hypothetical protein Rv2297 - none - gi|15609434 fig|83332.1.peg.2300 CDS NC_000962 2569080 2570051 3 + 972 hypothetical protein Rv2298 - none - gi|15609435 fig|83332.1.peg.2301 CDS NC_000962 2572000 2570057 -1 - 1944 Chaperone protein HtpG Protein chaperones gi|15609436 fig|83332.1.peg.2302 CDS NC_000962 2573006 2572074 -2 - 933 hypothetical protein Rv2300c - none - gi|15609437 fig|83332.1.peg.2303 CDS NC_000962 2573046 2573705 3 + 660 hypothetical protein Rv2301 - none - gi|15609438 fig|83332.1.peg.2304 CDS NC_000962 2573811 2574053 3 + 243 hypothetical protein Rv2302 - none - gi|15609439 fig|83332.1.peg.2305 CDS NC_000962 2575017 2574094 -3 - 924 hypothetical protein Rv2303c - none - gi|15609440 fig|83332.1.peg.2306 CDS NC_000962 2575223 2575014 -2 - 210 hypothetical protein Rv2304c - none - gi|15609441 fig|83332.1.peg.2307 CDS NC_000962 2575807 2577096 1 + 1290 hypothetical protein Rv2305 - none - gi|15609442 fig|83332.1.peg.2308 CDS NC_000962 2577818 2577192 -2 - 627 hypothetical protein Rv2306c - none - gi|15609443 fig|83332.1.peg.2309 CDS NC_000962 2578694 2577849 -2 - 846 hypothetical protein Rv2307c - none - gi|15609444 fig|83332.1.peg.2310 CDS NC_000962 2580417 2581133 3 + 717 hypothetical protein Rv2308 - none - gi|15609445 fig|83332.1.peg.2311 CDS NC_000962 2582296 2581841 -1 - 456 Integrase - none - gi|15609446 fig|83332.1.peg.2312 CDS NC_000962 2583433 2583777 1 + 345 DNA binding domain, excisionase family - none - gi|15609447 fig|83332.1.peg.2313 CDS NC_000962 2583882 2584406 3 + 525 Putative ATP-dependent exoDNAse - none - gi|15609448 fig|83332.1.peg.2314 CDS NC_000962 2584484 2584753 2 + 270 hypothetical protein Rv2312 - none - gi|15609449 fig|83332.1.peg.2315 CDS NC_000962 2585904 2585050 -3 - 855 hypothetical protein Rv2313c - none - gi|15609450 fig|83332.1.peg.2316 CDS NC_000962 2587288 2585915 -1 - 1374 TldE/PmbA family protein, Actinobacterial subgroup Putative TldE-TldD proteolytic complex gi|15609451 fig|83332.1.peg.2317 CDS NC_000962 2588802 2587285 -3 - 1518 TldD family protein, Actinobacterial subgroup Putative TldE-TldD proteolytic complex gi|15609452 fig|83332.1.peg.2318 CDS NC_000962 2588836 2589708 1 + 873 Multiple sugar ABC transporter, membrane-spanning permease protein MsmF - none - gi|15609453 fig|83332.1.peg.2319 CDS NC_000962 2589695 2590519 2 + 825 Sugar ABC transporter, permease protein - none - gi|15609454 fig|83332.1.peg.2320 CDS NC_000962 2590516 2591838 1 + 1323 Periplasmic sugar-binding lipoprotein UspC - none - gi|15609455 fig|83332.1.peg.2321 CDS NC_000962 2592724 2591846 -1 - 879 Universal stress protein family - none - gi|15609456 fig|83332.1.peg.2322 CDS NC_000962 2594151 2592721 -3 - 1431 Cationic amino acid transport integral membrane protein RocE - none - gi|15609457 fig|83332.1.peg.2323 CDS NC_000962 2594697 2594152 -3 - 546 Ornithine aminotransferase (EC 2.6.1.13) Proline, 4-hydroxyproline uptake and utilization gi|15609458 fig|83332.1.peg.2324 CDS NC_000962 2595362 2594697 -2 - 666 Ornithine aminotransferase (EC 2.6.1.13); N-terminus domain Arginine and Ornithine Degradation;
Dimethylarginine metabolism;
Proline, 4-hydroxyproline uptake and utilization gi|15609459 fig|83332.1.peg.2325 CDS NC_000962 2596267 2595359 -1 - 909 NG,NG-dimethylarginine dimethylaminohydrolase 1 (EC 3.5.3.18) Dimethylarginine metabolism gi|15609460 fig|83332.1.peg.2326 CDS NC_000962 2596332 2596778 3 + 447 Transcriptional regulator, AsnC family - none - gi|15609461 fig|83332.1.peg.2327 CDS NC_000962 2597855 2597007 -2 - 849 Transmembrane component of energizing module of ECF transporters in Mycobacteria ECF class transporters gi|15609462 fig|83332.1.peg.2328 CDS NC_000962 2599945 2597852 -1 - 2094 Candidate substrate-specific domain of ECF transporters in Mycobacteria / Duplicated ATPase component of energizing module of predicted ECF transporter in Mycobacteria ECF class transporters;
ECF class transporters gi|15609463 fig|83332.1.peg.2329 CDS NC_000962 2599986 2600477 3 + 492 Transcriptional regulator, MarR family - none - gi|15609464 fig|83332.1.peg.2330 CDS NC_000962 2600729 2601877 2 + 1149 PE family protein - none - gi|15609465 fig|83332.1.peg.2331 CDS NC_000962 2603459 2601912 -2 - 1548 Nitrate/nitrite transporter Nitrate and nitrite ammonification gi|15609466 fig|83332.1.peg.2332 CDS NC_000962 2604220 2603693 -1 - 528 Lipoprotein LppP - none - gi|15609467 fig|83332.1.peg.2333 CDS NC_000962 2604295 2604681 1 + 387 Assimilatory nitrate reductase large subunit (EC 1.7.99.4) - none - gi|15609468 fig|83332.1.peg.2334 CDS NC_000962 2604794 2606752 2 + 1959 NAD-dependent malic enzyme (EC 1.1.1.38) Pyruvate metabolism I: anaplerotic reactions, PEP gi|15609469 fig|83332.1.peg.2335 CDS NC_000962 2608319 2606706 -2 - 1614 Drug resistance transporter, EmrB/QacA subfamily - none - gi|15609470 fig|83332.1.peg.2336 CDS NC_000962 2608794 2609726 3 + 933 Cysteine synthase (EC 2.5.1.47) Cysteine Biosynthesis;
Methionine Biosynthesis gi|15609471 fig|83332.1.peg.2337 CDS NC_000962 2609730 2610419 3 + 690 Serine acetyltransferase (EC 2.3.1.30) Cysteine Biosynthesis;
Methionine Biosynthesis gi|15609472 fig|83332.1.peg.2338 CDS NC_000962 2610835 2611803 1 + 969 hypothetical protein Rv2336 - none - gi|15609473 fig|83332.1.peg.2339 CDS NC_000962 2612985 2611867 -3 - 1119 FIG031860: hypothetical protein - none - gi|15609474 fig|83332.1.peg.2340 CDS NC_000962 2614061 2613105 -2 - 957 Molybdopterin biosynthesis protein MoeW - none - gi|15609475 fig|83332.1.peg.2341 CDS NC_000962 2614691 2617579 2 + 2889 Transmembrane transport protein MmpL9 - none - gi|15609476 fig|83332.1.peg.2342 CDS NC_000962 2618906 2617665 -2 - 1242 PE family protein - none - gi|15609477 fig|83332.1.peg.2343 CDS NC_000962 2619595 2620014 1 + 420 Lipoprotein LppQ - none - gi|15609478 fig|83332.1.peg.2344 CDS NC_000962 2620270 2620527 1 + 258 hypothetical protein - none - gi|15609479 fig|83332.1.peg.2345 CDS NC_000962 2622450 2620531 -3 - 1920 DNA primase (EC 2.7.7.-) Macromolecular synthesis operon;
dNTP triphosphohydrolase protein family gi|15609480 fig|83332.1.peg.2346 CDS NC_000962 2623750 2622455 -1 - 1296 Deoxyguanosinetriphosphate triphosphohydrolase (EC 3.1.5.1) Purine conversions;
dNTP triphosphohydrolase protein family gi|15609481 fig|83332.1.peg.2347 CDS NC_000962 2623819 2625801 1 + 1983 Possible membrane protein - none - gi|15609482 fig|83332.1.peg.2348 CDS NC_000962 2626170 2625886 -3 - 285 ESAT-6-like protein EsxL Mycobacterium virulence operon with Esat6-like proteins;
Mycobacterium virulence operon with PE family and Esat6-like proteins gi|15609483 fig|83332.1.peg.2349 CDS NC_000962 2626517 2626221 -2 - 297 ESAT-6-like protein EsxK Mycobacterium virulence operon with Esat6-like proteins;
Mycobacterium virulence operon with PE family and Esat6-like proteins gi|15609484 fig|83332.1.peg.2350 CDS NC_000962 2626978 2626652 -1 - 327 FIG041762: hypothetical protein Mycobacterium virulence operon with Esat6-like proteins gi|15609485 fig|83332.1.peg.2351 CDS NC_000962 2628696 2627170 -3 - 1527 Phospholipase C 3 PlcC (EC 3.1.4.3) - none - gi|15609486 fig|83332.1.peg.2352 CDS NC_000962 2630317 2628779 -1 - 1539 Phospholipase C 2 PlcB (EC 3.1.4.3) - none - gi|15609487 fig|83332.1.peg.2353 CDS NC_000962 2632073 2630535 -2 - 1539 Phospholipase C 1 PlcA (EC 3.1.4.3) - none - gi|15609488 fig|83332.1.peg.2354 CDS NC_000962 2634096 2632921 -3 - 1176 PPE family protein - none - gi|15609489 fig|83332.1.peg.2355 CDS NC_000962 2635590 2634526 -3 - 1065 PPE family protein - none - gi|15609490 fig|83332.1.peg.2356 CDS NC_000962 2635626 2635952 3 + 327 Mobile element protein - none - gi|15609491 fig|83332.1.peg.2357 CDS NC_000962 2635949 2636887 2 + 939 Mobile element protein - none - gi|15609492 fig|83332.1.peg.2358 CDS NC_000962 2639533 2637686 -1 - 1848 PPE family protein - none - gi|15609493 fig|83332.1.peg.2359 CDS NC_000962 2641062 2639671 -3 - 1392 Glycyl-tRNA synthetase (EC 6.1.1.14) Glycyl-tRNA synthetase containing cluster;
tRNA aminoacylation, Gly gi|15609494 fig|83332.1.peg.2360 CDS NC_000962 2641244 2641651 2 + 408 Transcriptional regulator in glycyl-tRNA synthetase containing cluster Glycyl-tRNA synthetase containing cluster gi|15609495 fig|83332.1.peg.2361 CDS NC_000962 2641648 2642040 1 + 393 Zinc uptake regulation protein ZUR Glycyl-tRNA synthetase containing cluster;
Oxidative stress gi|15609496 fig|83332.1.peg.2362 CDS NC_000962 2642576 2642148 -2 - 429 FIG025412: hypothetical protein Glycyl-tRNA synthetase containing cluster gi|15609497 fig|83332.1.peg.2363 CDS NC_000962 2643466 2642576 -1 - 891 trans,polycis-decaprenyl diphosphate synthase [(2Z,6E)-farnesyl diphosphate specific] (EC 2.5.1.86) Glycyl-tRNA synthetase containing cluster;
Isoprenoinds for Quinones gi|15609498 fig|83332.1.peg.2364 CDS NC_000962 2644256 2643459 -2 - 798 DNA recombination and repair protein RecO CBSS-176299.4.peg.1292;
DNA repair, bacterial RecFOR pathway;
Glycyl-tRNA synthetase containing cluster gi|15609499 fig|83332.1.peg.2365 CDS NC_000962 2644318 2645772 1 + 1455 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases tRNA aminoacylation, Glu and Gln gi|15609500 fig|83332.1.peg.2366 CDS NC_000962 2646671 2645769 -2 - 903 GTP-binding protein Era Bacterial Cell Division;
CBSS-176299.4.peg.1292;
Glycyl-tRNA synthetase containing cluster;
Universal GTPases gi|15609501 fig|83332.1.peg.2367 CDS NC_000962 2647086 2646745 -3 - 342 FIG024795: hypothetical protein Glycyl-tRNA synthetase containing cluster gi|15609502 fig|83332.1.peg.2368 CDS NC_000962 2648365 2647058 -1 - 1308 Magnesium and cobalt efflux protein CorC CBSS-56780.10.peg.1536;
Glycyl-tRNA synthetase containing cluster;
Magnesium transport;
Phosphate metabolism gi|15609503 fig|83332.1.peg.2369 CDS NC_000962 2648910 2648362 -3 - 549 Metal-dependent hydrolase YbeY, involved in rRNA and/or ribosome maturation and assembly CBSS-56780.10.peg.1536;
Glycyl-tRNA synthetase containing cluster;
Phosphate metabolism gi|15609504 fig|83332.1.peg.2370 CDS NC_000962 2649972 2648914 -3 - 1059 Phosphate starvation-inducible protein PhoH, predicted ATPase CBSS-56780.10.peg.1536;
Glycyl-tRNA synthetase containing cluster;
Inteins;
Phosphate metabolism gi|15609505 fig|83332.1.peg.2371 CDS NC_000962 2650246 2649944 -1 - 303 hypothetical protein Rv2369c - none - gi|15609506 fig|83332.1.peg.2372 CDS NC_000962 2651556 2650243 -3 - 1314 Putative transcriptional activator protei - none - gi|15609507 fig|83332.1.peg.2373 CDS NC_000962 2651751 2651936 3 + 186 PE-PGRS FAMILY PROTEIN - none - gi|15609508 fig|83332.1.peg.2374 CDS NC_000962 2652823 2652035 -1 - 789 Ribosomal RNA small subunit methyltransferase E (EC 2.1.1.-) Heat shock dnaK gene cluster extended;
RNA methylation gi|15609509 fig|83332.1.peg.2375 CDS NC_000962 2653985 2652837 -2 - 1149 Chaperone protein DnaJ GroEL GroES;
Heat shock dnaK gene cluster extended;
Protein chaperones gi|15609510 fig|83332.1.peg.2376 CDS NC_000962 2655091 2654060 -1 - 1032 Heat-inducible transcription repressor HrcA GroEL GroES;
Heat shock dnaK gene cluster extended;
Heme and Siroheme Biosynthesis gi|15609511 fig|83332.1.peg.2377 CDS NC_000962 2655263 2655580 2 + 318 hypothetical protein Rv2375 - none - gi|15609512 fig|83332.1.peg.2378 CDS NC_000962 2656113 2655607 -3 - 507 Low molecular weight antigen MTB12 precursor - none - gi|15609513 fig|83332.1.peg.2379 CDS NC_000962 2656428 2656213 -3 - 216 Protein MbtH - none - gi|15609514 fig|83332.1.peg.2380 CDS NC_000962 2657701 2656406 -1 - 1296 L-lysine 6-monooxygenase MbtG (EC 1.14.13.59) - none - gi|15609515 fig|83332.1.peg.2381 CDS NC_000962 2662083 2657698 -3 - 4386 Peptide synthetase MbtF - none - gi|15609516 fig|83332.1.peg.2382 CDS NC_000962 2667113 2662065 -2 - 5049 Peptide synthetase MbtE - none - gi|15609517 fig|83332.1.peg.2383 CDS NC_000962 2670267 2667253 -3 - 3015 Polyketide synthetase MbtD - none - gi|15609518 fig|83332.1.peg.2384 CDS NC_000962 2671601 2670267 -2 - 1335 Polyketide synthetase MbtC Fatty Acid Biosynthesis FASII gi|15609519 fig|83332.1.peg.2385 CDS NC_000962 2675835 2671591 -3 - 4245 Phenyloxazoline synthase MbtB (EC 6.3.2.-) - none - gi|15609520 fig|83332.1.peg.2386 CDS NC_000962 2675934 2677631 3 + 1698 Bifunctional salicyl-AMP ligase/salicyl-S-arcp synthetase MbtA - none - gi|15609521 fig|83332.1.peg.2387 CDS NC_000962 2677727 2678647 2 + 921 Acetyl hydrolase MbtJ - none - gi|15609522 fig|83332.1.peg.2388 CDS NC_000962 2680003 2678651 -1 - 1353 isochorismate synthase MbtI - none - gi|15609523 fig|83332.1.peg.2389 CDS NC_000962 2680763 2682016 2 + 1254 putative sodium-dependent bicarbonate transporter - none - gi|15609524 fig|83332.1.peg.2390 CDS NC_000962 2683140 2682013 -3 - 1128 Hypothetical radical SAM family enzyme in heat shock gene cluster, similarity with CPO of BS HemN-type Heat shock dnaK gene cluster extended;
Heme and Siroheme Biosynthesis gi|15609525 fig|83332.1.peg.2391 CDS NC_000962 2683710 2683246 -3 - 465 Resuscitation-promoting factor RpfD - none - gi|15609526 fig|83332.1.peg.2392 CDS NC_000962 2684264 2683707 -2 - 558 Possible membrane protein - none - gi|15609527 fig|83332.1.peg.2393 CDS NC_000962 2684677 2686368 1 + 1692 Ferredoxin--sulfite reductase, actinobacterial type (EC 1.8.7.1) Inorganic Sulfur Assimilation;
WhiB and WhiB-type regulatory proteins gi|15609528 fig|83332.1.peg.2394 CDS NC_000962 2686365 2687129 3 + 765 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) Cysteine Biosynthesis;
Inorganic Sulfur Assimilation;
Inorganic Sulfur Assimilation gi|15609529 fig|83332.1.peg.2395 CDS NC_000962 2687126 2687971 2 + 846 Sirohydrochlorin ferrochelatase (EC 4.99.1.4) Heme and Siroheme Biosynthesis gi|15609530 fig|83332.1.peg.2396 CDS NC_000962 2688008 2689939 2 + 1932 Gamma-glutamyltranspeptidase (EC 2.3.2.2) - none - gi|15609531 fig|83332.1.peg.2397 CDS NC_000962 2690070 2692073 3 + 2004 Oligopeptide transporter - none - gi|15609532 fig|83332.1.peg.2398 CDS NC_000962 2692797 2693882 3 + 1086 PE family protein - none - gi|15609533 fig|83332.1.peg.2399 CDS NC_000962 2694962 2693907 -2 - 1056 Sulfate and thiosulfate import ATP-binding protein CysA (EC 3.6.3.25) Cysteine Biosynthesis;
Inorganic Sulfur Assimilation;
Uptake of selenate and selenite gi|15609534 fig|83332.1.peg.2400 CDS NC_000962 2695797 2694979 -3 - 819 Sulfate transport system permease protein CysW Cysteine Biosynthesis;
Inorganic Sulfur Assimilation gi|15609535 fig|83332.1.peg.2401 CDS NC_000962 2696645 2695794 -2 - 852 Sulfate transport system permease protein CysT Cysteine Biosynthesis;
Inorganic Sulfur Assimilation gi|15609536 fig|83332.1.peg.2402 CDS NC_000962 2697712 2696642 -1 - 1071 Sulfate and thiosulfate binding protein CysP Cysteine Biosynthesis;
Inorganic Sulfur Assimilation gi|15609537 fig|83332.1.peg.2403 CDS NC_000962 2697837 2698055 3 + 219 FIG00825228: hypothetical protein - none - gi|15609538 fig|83332.1.peg.2404 CDS NC_000962 2698527 2700455 3 + 1929 Glucoamylase (EC 3.2.1.3) - none - gi|15609539 fig|83332.1.peg.2405 CDS NC_000962 2701288 2700533 -1 - 756 Lipoprotein LppR - none - gi|15609540 fig|83332.1.peg.2406 CDS NC_000962 2703246 2701285 -3 - 1962 Translation elongation factor LepA Heat shock dnaK gene cluster extended;
Heme and Siroheme Biosynthesis;
Translation elongation factors bacterial;
Universal GTPases gi|15609541 fig|83332.1.peg.2407 CDS NC_000962 2703267 2703836 3 + 570 RNA 3'-terminal phosphate cyclase (EC 6.5.1.4) RNA 3'-terminal phosphate cyclase;
tRNA splicing gi|15609542 fig|83332.1.peg.2408 CDS NC_000962 2704435 2704007 -1 - 429 CBS domain protein - none - gi|15609543 fig|83332.1.peg.2409 CDS NC_000962 2704695 2705516 3 + 822 metallo-beta-lactamase family protein - none - gi|15609544 fig|83332.1.peg.2410 CDS NC_000962 2706015 2706734 3 + 720 PE family protein - none - gi|15609545 fig|83332.1.peg.2411 CDS NC_000962 2707331 2706492 -2 - 840 Protein containing transglutaminase-like domain, putative cysteine protease - none - gi|15609546 fig|83332.1.peg.2412 CDS NC_000962 2708308 2707331 -1 - 978 Protein containing domains DUF403 - none - gi|15609547 fig|83332.1.peg.2413 CDS NC_000962 2709963 2708308 -3 - 1656 Protein containing domains DUF404, DUF407 - none - gi|15609548 fig|83332.1.peg.2414 CDS NC_000962 2710073 2710333 2 + 261 SSU ribosomal protein S20p Ribosome SSU bacterial gi|15609549 fig|83332.1.peg.2415 CDS NC_000962 2711299 2710349 -1 - 951 DNA polymerase III delta subunit (EC 2.7.7.7) - none - gi|15609550 fig|83332.1.peg.2416 CDS NC_000962 2712874 2711330 -1 - 1545 DNA internalization-related competence protein ComEC/Rec2 - none - gi|15609551 fig|83332.1.peg.2417 CDS NC_000962 2713782 2712889 -3 - 894 Putative competence protein ComEA - none - gi|15609552 fig|83332.1.peg.2418 CDS NC_000962 2715348 2714122 -3 - 1227 Enhanced intracellular survival protein - none - gi|15609553 fig|83332.1.peg.2419 CDS NC_000962 2716312 2715470 -1 - 843 Hypothetical protein DUF194, DegV family - none - gi|15609554 fig|83332.1.peg.2420 CDS NC_000962 2717136 2716393 -3 - 744 hypothetical protein - none - gi|15609555 fig|83332.1.peg.2421 CDS NC_000962 2717797 2717126 -1 - 672 Phosphoglycerate mutase family Phosphoglycerate mutase protein family gi|15609556 fig|83332.1.peg.2422 CDS NC_000962 2718174 2717794 -3 - 381 Iojap protein NAD and NADP cofactor biosynthesis global;
tRNA modification Bacteria gi|15609557 fig|83332.1.peg.2423 CDS NC_000962 2718806 2718171 -2 - 636 Nicotinate-nucleotide adenylyltransferase (EC 2.7.7.18) ## bacterial NadD family NAD and NADP cofactor biosynthesis global gi|15609558 fig|83332.1.peg.2424 CDS NC_000962 2719081 2719353 1 + 273 hypothetical protein - none - gi|15609559 fig|83332.1.peg.2425 CDS NC_000962 2719595 2720641 2 + 1047 SAM-dependent methyltransferases - none - gi|15609560 fig|83332.1.peg.2426 CDS NC_000962 2721775 2720774 -1 - 1002 Mobile element protein - none - gi|15609561 fig|83332.1.peg.2427 CDS NC_000962 2723306 2721864 -2 - 1443 VWA containing CoxE family protein - none - gi|15609562 fig|83332.1.peg.2428 CDS NC_000962 2724181 2723306 -1 - 876 MoxR-like ATPases - none - gi|15609563 fig|83332.1.peg.2429 CDS NC_000962 2725475 2724228 -2 - 1248 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) Proline, 4-hydroxyproline uptake and utilization;
Proline Synthesis gi|15609564 fig|83332.1.peg.2430 CDS NC_000962 2726191 2726778 1 + 588 Alkyl hydroperoxide reductase protein C (EC 1.6.4.-) Thioredoxin-disulfide reductase gi|15609565 fig|83332.1.peg.2431 CDS NC_000962 2726804 2727337 2 + 534 Alkylhydroperoxidase protein D Thioredoxin-disulfide reductase gi|15609566 fig|83332.1.peg.2432 CDS NC_000962 2727918 2727334 -3 - 585 PPE family protein CBSS-164757.7.peg.5020 gi|15609567 fig|83332.1.peg.2433 CDS NC_000962 2728264 2727965 -1 - 300 PE family protein - none - gi|15609568 fig|83332.1.peg.2434 CDS NC_000962 2728845 2728435 -3 - 411 hypothetical protein Rv2432c - none - gi|15609569 fig|83332.1.peg.2435 CDS NC_000962 2729132 2728842 -2 - 291 hypothetical protein Rv2433c - none - gi|15609570 fig|83332.1.peg.2436 CDS NC_000962 2730558 2729113 -3 - 1446 Small-conductance mechanosensitive channel membrane protein - none - gi|15609571 fig|83332.1.peg.2437 CDS NC_000962 2732747 2730555 -2 - 2193 Adenylate cyclase (EC 4.6.1.1) cAMP signaling in bacteria gi|15609572 fig|83332.1.peg.2438 CDS NC_000962 2733228 2734142 3 + 915 Ribokinase (EC 2.7.1.15) D-ribose utilization;
Deoxyribose and Deoxynucleoside Catabolism gi|15609573 fig|83332.1.peg.2439 CDS NC_000962 2734374 2734793 3 + 420 Putative protein-S-isoprenylcysteine methyltransferase - none - gi|15609574 fig|83332.1.peg.2440 CDS NC_000962 2737006 2734790 -1 - 2217 NAD synthetase (EC 6.3.1.5) / Glutamine amidotransferase chain of NAD synthetase NAD and NADP cofactor biosynthesis global;
NAD and NADP cofactor biosynthesis global gi|15609575 fig|83332.1.peg.2441 CDS NC_000962 2738245 2737115 -1 - 1131 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA Proline, 4-hydroxyproline uptake and utilization;
Proline Synthesis;
Proline Synthesis gi|15609576 fig|83332.1.peg.2442 CDS NC_000962 2739684 2738245 -3 - 1440 GTP-binding protein Obg CBSS-176279.3.peg.868;
Universal GTPases gi|15609577 fig|83332.1.peg.2443 CDS NC_000962 2740030 2739770 -1 - 261 LSU ribosomal protein L27p CBSS-176279.3.peg.868;
Ribosome LSU bacterial gi|15609578 fig|83332.1.peg.2444 CDS NC_000962 2740359 2740045 -3 - 315 LSU ribosomal protein L21p CBSS-176279.3.peg.868;
Ribosome LSU bacterial gi|15609579 fig|83332.1.peg.2445 CDS NC_000962 2740707 2742182 3 + 1476 C4-dicarboxylate-transport transmembrane protein DctA - none - gi|15609580 fig|83332.1.peg.2446 CDS NC_000962 2744982 2742121 -3 - 2862 Ribonuclease E (EC 3.1.26.12) RNA processing and degradation, bacterial;
Ribosome biogenesis bacterial gi|15609581 fig|83332.1.peg.2447 CDS NC_000962 2745722 2745312 -2 - 411 Nucleoside diphosphate kinase (EC 2.7.4.6) Purine conversions;
pyrimidine conversions gi|15609582 fig|83332.1.peg.2448 CDS NC_000962 2746136 2745765 -2 - 372 Possible membrane protein - none - gi|15609583 fig|83332.1.peg.2449 CDS NC_000962 2747596 2746133 -1 - 1464 Dihydrofolate synthase (EC 6.3.2.12) @ Folylpolyglutamate synthase (EC 6.3.2.17) Folate Biosynthesis;
Folate Biosynthesis gi|15609584 fig|83332.1.peg.2450 CDS NC_000962 2750223 2747593 -3 - 2631 Valyl-tRNA synthetase (EC 6.1.1.9) tRNA aminoacylation, Val gi|15609585 fig|83332.1.peg.2451 CDS NC_000962 2751570 2750311 -3 - 1260 Possible membrane protein - none - gi|15609586 fig|83332.1.peg.2452 CDS NC_000962 2752178 2751660 -2 - 519 Putative saccharopine dehydrogenase - none - gi|15609587 fig|83332.1.peg.2453 CDS NC_000962 2752260 2752658 3 + 399 hypothetical protein Rv2451 - none - gi|15609588 fig|83332.1.peg.2454 CDS NC_000962 2752992 2752846 -3 - 147 FIG070430: hypothetical protein - none - gi|15609589 fig|83332.1.peg.2455 CDS NC_000962 2753621 2753016 -2 - 606 Molybdopterin-guanine dinucleotide biosynthesis protein MobA Molybdenum cofactor biosynthesis;
ar-431-EC Molybdopterin-guanine dinucleotide biosynthesis gi|15609590 fig|83332.1.peg.2456 CDS NC_000962 2754744 2753623 -3 - 1122 2-oxoglutarate oxidoreductase, beta subunit (EC 1.2.7.3) TCA Cycle gi|15609591 fig|83332.1.peg.2457 CDS NC_000962 2756702 2754741 -2 - 1962 2-oxoglutarate oxidoreductase, alpha subunit (EC 1.2.7.3) TCA Cycle gi|15609592 fig|83332.1.peg.2458 CDS NC_000962 2758190 2756934 -2 - 1257 Integral membrane transport protein - none - gi|15609593 fig|83332.1.peg.2459 CDS NC_000962 2759486 2758206 -2 - 1281 ATP-dependent Clp protease ATP-binding subunit ClpX Proteolysis in bacteria, ATP-dependent gi|15609594 fig|83332.1.peg.2460 CDS NC_000962 2759777 2760685 2 + 909 Homocysteine S-methyltransferase (EC 2.1.1.10) Methionine Biosynthesis gi|15609595 fig|83332.1.peg.2461 CDS NC_000962 2760852 2762378 3 + 1527 Multidrug resistance integral membrane efflux protein EmrB - none - gi|15609596 fig|83332.1.peg.2462 CDS NC_000962 2763173 2762529 -2 - 645 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) Proteolysis in bacteria, ATP-dependent;
cAMP signaling in bacteria gi|15609597 fig|83332.1.peg.2463 CDS NC_000962 2763772 2763170 -1 - 603 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) Proteolysis in bacteria, ATP-dependent;
cAMP signaling in bacteria gi|15609598 fig|83332.1.peg.2464 CDS NC_000962 2765289 2763889 -3 - 1401 Cell division trigger factor (EC 5.2.1.8) Bacterial Cell Division gi|15609599 fig|83332.1.peg.2465 CDS NC_000962 2765653 2766837 1 + 1185 Esterase A - none - gi|15609600 fig|83332.1.peg.2466 CDS NC_000962 2767663 2766857 -1 - 807 Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23) DNA Repair Base Excision gi|15609601 fig|83332.1.peg.2467 CDS NC_000962 2768157 2767669 -3 - 489 Ribose 5-phosphate isomerase B (EC 5.3.1.6) / Galactose 6-phosphate isomerase D-ribose utilization;
Pentose phosphate pathway gi|15609602 fig|83332.1.peg.2468 CDS NC_000962 2768882 2768259 -2 - 624 hypothetical protein Rv2466c - none - gi|15609603 fig|83332.1.peg.2469 CDS NC_000962 2768984 2771569 2 + 2586 Membrane alanine aminopeptidase N (EC 3.4.11.2) - none - gi|15609604 fig|83332.1.peg.2470 CDS NC_000962 2772145 2771642 -1 - 504 hypothetical protein Rv2468c - none - gi|15609605 fig|83332.1.peg.2471 CDS NC_000962 2773033 2772365 -1 - 669 HNH endonuclease family protein - none - gi|15609606 fig|83332.1.peg.2472 CDS NC_000962 2773176 2773562 3 + 387 Hemoglobin-like protein HbO Bacterial hemoglobins gi|15609607 fig|83332.1.peg.2473 CDS NC_000962 2773562 2775202 2 + 1641 Alpha-glucosidase (EC 3.2.1.20) - none - gi|15609608 fig|83332.1.peg.2474 CDS NC_000962 2775270 2775563 3 + 294 hypothetical protein - none - gi|15609609 fig|83332.1.peg.2475 CDS NC_000962 2775566 2776282 2 + 717 Alanine and proline rich membrane protein - none - gi|15609610 fig|83332.1.peg.2476 CDS NC_000962 2776967 2776314 -2 - 654 hypothetical protein Rv2474c - none - gi|15609611 fig|83332.1.peg.2477 CDS NC_000962 2777389 2776973 -1 - 417 hypothetical protein Rv2475c - none - gi|15609612 fig|83332.1.peg.2478 CDS NC_000962 2782260 2777386 -3 - 4875 NAD-specific glutamate dehydrogenase (EC 1.4.1.2), large form Glutamate dehydrogenases;
Glutamine, Glutamate, Aspartate and Asparagine Biosynthesis gi|15609613 fig|83332.1.peg.2479 CDS NC_000962 2784040 2782364 -1 - 1677 ABC transporter ATP-binding protein - none - gi|15609614 fig|83332.1.peg.2480 CDS NC_000962 2784606 2784121 -3 - 486 Single-strand DNA binding protein - none - gi|15609615 fig|83332.1.peg.2481 CDS NC_000962 2785695 2784655 -3 - 1041 Mobile element protein - none - gi|15609616 fig|83332.1.peg.2482 CDS NC_000962 2785916 2785590 -2 - 327 Mobile element protein - none - gi|15609617 fig|83332.1.peg.2483 CDS NC_000962 2786896 2786573 -1 - 324 hypothetical protein Rv2481c - none - gi|15609618 fig|83332.1.peg.2484 CDS NC_000962 2789281 2786912 -1 - 2370 Glycerol-3-phosphate acyltransferase (EC 2.3.1.15) Glycerolipid and Glycerophospholipid Metabolism in Bacteria gi|15609619 fig|83332.1.peg.2485 CDS NC_000962 2791020 2789278 -3 - 1743 Phosphoserine phosphatase (EC 3.1.3.3) / 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51) CBSS-336982.3.peg.3874;
Glycerolipid and Glycerophospholipid Metabolism in Bacteria;
Glycine and Serine Utilization;
Phosphate metabolism;
Ribosome post-transcriptional modification and chromosomal segregation cluster;
Serine Biosynthesis gi|15609620 fig|83332.1.peg.2486 CDS NC_000962 2792492 2791017 -2 - 1476 Acyltransferase, ws/dgat/mgat subfamily protein - none - gi|15609621 fig|83332.1.peg.2487 CDS NC_000962 2793986 2792721 -2 - 1266 Carboxylesterase LipQ - none - gi|15609622 fig|83332.1.peg.2488 CDS NC_000962 2794348 2795118 1 + 771 Enoyl-CoA hydratase (EC 4.2.1.17) Acetyl-CoA fermentation to Butyrate;
Butanol Biosynthesis;
Fatty acid metabolism cluster;
Isoleucine degradation;
Polyhydroxybutyrate metabolism;
Valine degradation gi|15609623 fig|83332.1.peg.2489 CDS NC_000962 2797383 2795299 -3 - 2085 PE family protein - none - gi|15609624 fig|83332.1.peg.2490 CDS NC_000962 2800878 2797465 -3 - 3414 Adenylyl cyclase class-3/4/guanylyl cyclase / Disease resistance domain-containing protein / Tetratricopeptide repeat-containing protein / Transcriptional regulator, LuxR family - none - gi|15609625 fig|83332.1.peg.2491 CDS NC_000962 2801143 2800844 -1 - 300 FIG00821546: hypothetical protein - none - gi|15609626 fig|83332.1.peg.2492 CDS NC_000962 2806234 2801252 -1 - 4983 PE family protein - none - gi|15609627 fig|83332.1.peg.2493 CDS NC_000962 2806663 2807286 1 + 624 Rossmann-fold nucleotide-binding protein - none - gi|15609628 fig|83332.1.peg.2494 CDS NC_000962 2807276 2808028 2 + 753 hypothetical protein Rv2492 - none - gi|15609629 fig|83332.1.peg.2495 CDS NC_000962 2808081 2808302 3 + 222 Antitoxin 1 Toxin-Antitoxin MT1 gi|15609630 fig|83332.1.peg.2496 CDS NC_000962 2808308 2808733 2 + 426 Toxin 1, PIN domain Toxin-Antitoxin MT1 gi|15609631 fig|83332.1.peg.2497 CDS NC_000962 2809937 2808756 -2 - 1182 Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168) Dehydrogenase complexes;
Isoleucine degradation;
Leucine Degradation and HMG-CoA Metabolism;
Lipoic acid metabolism;
Valine degradation gi|15609632 fig|83332.1.peg.2498 CDS NC_000962 2810980 2809934 -1 - 1047 Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4) Dehydrogenase complexes;
Isoleucine degradation;
Leucine Degradation and HMG-CoA Metabolism;
Valine degradation gi|15609633 fig|83332.1.peg.2499 CDS NC_000962 2812094 2810991 -2 - 1104 Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4) Dehydrogenase complexes;
Isoleucine degradation;
Leucine Degradation and HMG-CoA Metabolism;
Valine degradation gi|15609634 fig|83332.1.peg.2500 CDS NC_000962 2813174 2812353 -2 - 822 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) HMG CoA Synthesis;
Leucine Degradation and HMG-CoA Metabolism gi|15609635 fig|83332.1.peg.2501 CDS NC_000962 2813728 2813171 -1 - 558 Oxidase regulatory-related protein - none - gi|15609636 fig|83332.1.peg.2502 CDS NC_000962 2814909 2813725 -3 - 1185 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) HMG CoA Synthesis;
Leucine Degradation and HMG-CoA Metabolism gi|15609637 fig|83332.1.peg.2503 CDS NC_000962 2816878 2814914 -1 - 1965 Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4) HMG CoA Synthesis;
Leucine Degradation and HMG-CoA Metabolism;
Serine-glyoxylate cycle gi|15609638 fig|83332.1.peg.2504 CDS NC_000962 2818472 2816883 -2 - 1590 Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4) HMG CoA Synthesis;
Leucine Degradation and HMG-CoA Metabolism;
Serine-glyoxylate cycle gi|15609639 fig|83332.1.peg.2505 CDS NC_000962 2819125 2818469 -1 - 657 Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B (EC 2.8.3.5) Catechol branch of beta-ketoadipate pathway;
Leucine Degradation and HMG-CoA Metabolism;
Polyhydroxybutyrate metabolism;
Serine-glyoxylate cycle gi|15609640 fig|83332.1.peg.2506 CDS NC_000962 2819868 2819122 -3 - 747 Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (EC 2.8.3.5) Catechol branch of beta-ketoadipate pathway;
Leucine Degradation and HMG-CoA Metabolism;
Polyhydroxybutyrate metabolism;
Serine-glyoxylate cycle gi|15609641 fig|83332.1.peg.2507 CDS NC_000962 2821594 2819951 -1 - 1644 Acetoacetyl-CoA synthetase (EC 6.2.1.16) / Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) Biotin biosynthesis;
Biotin synthesis cluster;
Fatty acid metabolism cluster;
HMG CoA Synthesis;
Leucine Degradation and HMG-CoA Metabolism;
Polyhydroxybutyrate metabolism gi|15609642 fig|83332.1.peg.2508 CDS NC_000962 2821710 2822357 3 + 648 Transcriptional regulator, TetR family - none - gi|15609643 fig|83332.1.peg.2509 CDS NC_000962 2822436 2823257 3 + 822 hypothetical protein Rv2507 - none - gi|15609644 fig|83332.1.peg.2510 CDS NC_000962 2824591 2823254 -1 - 1338 Permease of the major facilitator transporter superfamily - none - gi|15609645 fig|83332.1.peg.2511 CDS NC_000962 2824676 2825482 2 + 807 Short-chain dehydrogenase/reductase SDR - none - gi|15609646 fig|83332.1.peg.2512 CDS NC_000962 2827087 2825486 -1 - 1602 ATPase - none - gi|15609647 fig|83332.1.peg.2513 CDS NC_000962 2827155 2827802 3 + 648 3'-to-5' oligoribonuclease (orn) RNA processing and degradation, bacterial gi|15609648 fig|83332.1.peg.2514 CDS NC_000962 2829801 2828554 -3 - 1248 Mobile element protein - none - gi|15609649 fig|83332.1.peg.2515 CDS NC_000962 2830159 2830581 1 + 423 hypothetical protein Rv2513 - none - gi|15609650 fig|83332.1.peg.2516 CDS NC_000962 2831336 2830875 -2 - 462 hypothetical protein Rv2514c - none - gi|15609651 fig|83332.1.peg.2517 CDS NC_000962 2832589 2831342 -1 - 1248 DNA-binding protein - none - gi|15609652 fig|83332.1.peg.2518 CDS NC_000962 2833511 2832765 -2 - 747 FIG00821793: hypothetical protein - none - gi|15609653 fig|83332.1.peg.2519 CDS NC_000962 2833759 2833508 -1 - 252 FIG00820249: hypothetical protein - none - gi|15609654 fig|83332.1.peg.2520 CDS NC_000962 2835333 2834107 -3 - 1227 Lipoprotein LppS - none - gi|15609655 fig|83332.1.peg.2521 CDS NC_000962 2835783 2837261 3 + 1479 PE family protein - none - gi|15609656 fig|83332.1.peg.2522 CDS NC_000962 2837613 2837386 -3 - 228 POSSIBLE CONSERVED MEMBRANE PROTEIN - none - gi|15609657 fig|83332.1.peg.2523 CDS NC_000962 2837682 2838155 3 + 474 Thiol peroxidase, Bcp-type (EC 1.11.1.15) Thioredoxin-disulfide reductase gi|15609658 fig|83332.1.peg.2524 CDS NC_000962 2839539 2838127 -3 - 1413 N-acyl-L-amino acid amidohydrolase (EC 3.5.1.14) - none - gi|15609659 fig|83332.1.peg.2525 CDS NC_000962 2839928 2839536 -2 - 393 Holo-[acyl-carrier protein] synthase (EC 2.7.8.7) CBSS-176299.4.peg.1292;
Fatty Acid Biosynthesis FASII gi|15609660 fig|83332.1.peg.2526 CDS NC_000962 2849330 2840121 -2 - 9210 [Acyl-carrier-protein] acetyl transferase of FASI (EC 2.3.1.38) / Enoyl-[acyl-carrier-protein] reductase of FASI (EC 1.3.1.9) / 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase of FASI (EC 4.2.1.61) / [Acyl-carrier-protein] malonyl transferase of FASI (EC 2.3.1.39) / [Acyl-carrier-protein] palmitoyl transferase of FASI (EC 2.3.1.-) / Acyl carrier protein of FASI / 3-oxoacyl-[acyl-carrier-protein] reductase of FASI (EC 1.1.1.100) / 3-oxoacyl-[acyl-carrier-protein] synthase of FASI (EC 2.3.1.41) - none - gi|15609661 fig|83332.1.peg.2527 CDS NC_000962 2850572 2849850 -2 - 723 Putative secreted protein - none - gi|15609662 fig|83332.1.peg.2528 CDS NC_000962 2851089 2851316 3 + 228 hypothetical protein - none - gi|15609663 fig|83332.1.peg.2529 CDS NC_000962 2851313 2851714 2 + 402 hypothetical protein - none - gi|15609664 fig|83332.1.peg.2530 CDS NC_000962 2852669 2851749 -2 - 921 Mrr restriction system protein - none - gi|15609665 fig|83332.1.peg.2531 CDS NC_000962 2852873 2854264 2 + 1392 ERCC4 domain-containing protein - none - gi|15609666 fig|83332.1.peg.2532 CDS NC_000962 2854684 2854265 -1 - 420 Toxin 1, PIN domain Toxin-Antitoxin MT1 gi|15609667 fig|83332.1.peg.2533 CDS NC_000962 2857779 2854936 -3 - 2844 Arginine decarboxylase (EC 4.1.1.19) Polyamine Metabolism gi|15609668 fig|83332.1.peg.2534 CDS NC_000962 2858252 2857851 -2 - 402 Transcription termination protein NusB - none - gi|15609669 fig|83332.1.peg.2535 CDS NC_000962 2858722 2858252 -1 - 471 Transcription termination protein NusB Riboflavin synthesis cluster;
Transcription factors bacterial gi|15609670 fig|83332.1.peg.2536 CDS NC_000962 2859288 2858725 -3 - 564 Translation elongation factor P Translation elongation factors bacterial gi|15609671 fig|83332.1.peg.2537 CDS NC_000962 2860416 2859298 -3 - 1119 Aminopeptidase YpdF (MP-, MA-, MS-, AP-, NP- specific) Protein degradation gi|15609672 fig|83332.1.peg.2538 CDS NC_000962 2860450 2861142 1 + 693 Possible membrane protein - none - gi|15609673 fig|83332.1.peg.2539 CDS NC_000962 2861589 2861146 -3 - 444 3-dehydroquinate dehydratase II (EC 4.2.1.10) # AroC II Chorismate Synthesis;
Common Pathway For Synthesis of Aromatic Compounds (DAHP synthase to chorismate);
Quinate degradation gi|15609674 fig|83332.1.peg.2540 CDS NC_000962 2862674 2861586 -2 - 1089 3-dehydroquinate synthase (EC 4.2.3.4) # AroB Chorismate Synthesis;
Common Pathway For Synthesis of Aromatic Compounds (DAHP synthase to chorismate) gi|15609675 fig|83332.1.peg.2541 CDS NC_000962 2863201 2862671 -1 - 531 Shikimate kinase I (EC 2.7.1.71) # AroE I Cell envelope-associated LytR-CpsA-Psr transcriptional attenuators;
Chorismate Synthesis;
Common Pathway For Synthesis of Aromatic Compounds (DAHP synthase to chorismate) gi|15609676 fig|83332.1.peg.2542 CDS NC_000962 2864410 2863205 -1 - 1206 Chorismate synthase (EC 4.2.3.5) # AroG Chorismate Synthesis;
Common Pathway For Synthesis of Aromatic Compounds (DAHP synthase to chorismate) gi|15609677 fig|83332.1.peg.2543 CDS NC_000962 2864425 2864832 1 + 408 FIG00824306: hypothetical protein - none - gi|15609678 fig|83332.1.peg.2544 CDS NC_000962 2865128 2866339 2 + 1212 POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN - none - gi|15609679 fig|83332.1.peg.2545 CDS NC_000962 2866466 2867125 2 + 660 Lipoprotein LppA - none - gi|15609680 fig|83332.1.peg.2546 CDS NC_000962 2867122 2867784 1 + 663 Lipoprotein LppA - none - gi|15609681 fig|83332.1.peg.2547 CDS NC_000962 2867781 2868059 3 + 279 hypothetical protein Rv2545 - none - gi|15609682 fig|83332.1.peg.2548 CDS NC_000962 2868152 2868565 2 + 414 POSSIBLE CONSERVED MEMBRANE PROTEIN - none - gi|15609683 fig|83332.1.peg.2549 CDS NC_000962 2868604 2868861 1 + 258 DNA-binding protein, CopG family - none - gi|15609684 fig|83332.1.peg.2550 CDS NC_000962 2868858 2869235 3 + 378 PIN domain protein - none - gi|15609685 fig|83332.1.peg.2551 CDS NC_000962 2870120 2869725 -2 - 396 hypothetical protein Rv2549c - none - gi|15609686 fig|83332.1.peg.2552 CDS NC_000962 2870362 2870117 -1 - 246 DNA-binding protein, CopG family - none - gi|15609687 fig|83332.1.peg.2553 CDS NC_000962 2871192 2870773 -3 - 420 probable type IV peptidase - none - gi|15609688 fig|83332.1.peg.2554 CDS NC_000962 2872013 2871204 -2 - 810 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) # AroDI alpha Chorismate Synthesis;
Cluster containing Alanyl-tRNA synthetase;
Common Pathway For Synthesis of Aromatic Compounds (DAHP synthase to chorismate) gi|15609689 fig|83332.1.peg.2555 CDS NC_000962 2873263 2872010 -1 - 1254 FIG004453: protein YceG like Cluster containing Alanyl-tRNA synthetase;
tRNA modification Bacteria gi|15609690 fig|83332.1.peg.2556 CDS NC_000962 2873768 2873256 -2 - 513 Putative Holliday junction resolvase YggF Cluster containing Alanyl-tRNA synthetase gi|15609691 fig|83332.1.peg.2557 CDS NC_000962 2876483 2873769 -2 - 2715 Alanyl-tRNA synthetase (EC 6.1.1.7) Cluster containing Alanyl-tRNA synthetase;
tRNA aminoacylation, Ala gi|15609692 fig|83332.1.peg.2558 CDS NC_000962 2876963 2876574 -2 - 390 FIG027887: hypothetical protein - none - gi|15609693 fig|83332.1.peg.2559 CDS NC_000962 2877070 2877744 1 + 675 hypothetical protein Rv2558 - none - gi|15609694 fig|83332.1.peg.2560 CDS NC_000962 2877829 2878539 1 + 711 Hypothetical protein Rv2558 - none - gi|15609695 fig|83332.1.peg.2561 CDS NC_000962 2879927 2878569 -2 - 1359 ATPase, AAA family - none - gi|15609696 fig|83332.1.peg.2562 CDS NC_000962 2880073 2881050 1 + 978 PROBABLE PROLINE AND GLYCINE RICH TRANSMEMBRANE PROTEIN - none - gi|15609697 fig|83332.1.peg.2563 CDS NC_000962 2881407 2881700 3 + 294 hypothetical protein - none - gi|15609698 fig|83332.1.peg.2564 CDS NC_000962 2881756 2882145 1 + 390 hypothetical protein - none - gi|15609699 fig|83332.1.peg.2565 CDS NC_000962 2882288 2883337 2 + 1050 Glutamine-transport transmembrane protein ABC transporter - none - gi|15609700 fig|83332.1.peg.2566 CDS NC_000962 2883340 2884332 1 + 993 Glutamine-transport ATP-binding protein ABC transporter GlnQ - none - gi|15609701 fig|83332.1.peg.2567 CDS NC_000962 2884609 2886360 1 + 1752 Uncharacterized NTE family protein - none - gi|15609702 fig|83332.1.peg.2568 CDS NC_000962 2886371 2889793 2 + 3423 Large protein containing transglutaminase-like domain - none - gi|15609703 fig|83332.1.peg.2569 CDS NC_000962 2889793 2892447 1 + 2655 Protein containing domains DUF404, DUF407, DUF403 - none - gi|15609704 fig|83332.1.peg.2570 CDS NC_000962 2893469 2892451 -2 - 1019 hypothetical protein - none - gi|15609705 fig|83332.1.peg.2571 CDS NC_000962 2894406 2893462 -3 - 945 Protein containing transglutaminase-like domain, putative cysteine protease - none - gi|15609706 fig|83332.1.peg.2572 CDS NC_000962 2894510 2894899 2 + 390 FIG00822845: hypothetical protein - none - gi|15609707 fig|83332.1.peg.2573 CDS NC_000962 2895958 2894891 -1 - 1068 Possible membrane protein - none - gi|15609708 fig|83332.1.peg.2574 CDS NC_000962 2897801 2896011 -2 - 1791 Aspartyl-tRNA synthetase (EC 6.1.1.12) @ Aspartyl-tRNA(Asn) synthetase (EC 6.1.1.23) ## unambiguous tRNA aminoacylation, Asp and Asn;
tRNA aminoacylation, Asp and Asn gi|15609709 fig|83332.1.peg.2575 CDS NC_000962 2898041 2898781 2 + 741 2-dehydropantoate 2-reductase (EC 1.1.1.169) 16S rRNA modification within P site of ribosome;
Coenzyme A Biosynthesis gi|15609710 fig|83332.1.peg.2576 CDS NC_000962 2898804 2899307 3 + 504 hypothetical protein - none - gi|15609711 fig|83332.1.peg.2577 CDS NC_000962 2899337 2900218 2 + 882 YpfJ protein, zinc metalloprotease superfamily Broadly distributed proteins not in subsystems gi|15609712 fig|83332.1.peg.2578 CDS NC_000962 2900688 2900224 -3 - 465 Possible membrane protein - none - gi|15609713 fig|83332.1.peg.2579 CDS NC_000962 2900916 2902505 3 + 1590 Purple acid phosphatase - none - gi|15609714 fig|83332.1.peg.2580 CDS NC_000962 2903529 2902507 -3 - 1023 Radical SAM domain protein - none - gi|15609715 fig|83332.1.peg.2581 CDS NC_000962 2903637 2904539 3 + 903 Haloalkane dehalogenase (EC 3.8.1.5) - none - gi|15609716 fig|83332.1.peg.2582 CDS NC_000962 2906090 2904819 -2 - 1272 Histidyl-tRNA synthetase (EC 6.1.1.21) Histidine Biosynthesis;
Stringent Response, (p)ppGpp metabolism;
tRNA aminoacylation, His gi|15609717 fig|83332.1.peg.2583 CDS NC_000962 2906761 2906087 -1 - 675 Hydroxyacylglutathione hydrolase (EC 3.1.2.6) - none - gi|15609718 fig|83332.1.peg.2584 CDS NC_000962 2906812 2907738 1 + 927 Peptidyl-prolyl cis-trans isomerase B (EC 5.2.1.8) - none - gi|15609719 fig|83332.1.peg.2585 CDS NC_000962 2910196 2907824 -1 - 2373 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I CBSS-176299.4.peg.1292;
Stringent Response, (p)ppGpp metabolism gi|15609720 fig|83332.1.peg.2586 CDS NC_000962 2910898 2910227 -1 - 672 Adenine phosphoribosyltransferase (EC 2.4.2.7) Purine conversions;
Stringent Response, (p)ppGpp metabolism;
cAMP signaling in bacteria gi|15609721 fig|83332.1.peg.2587 CDS NC_000962 2912675 2911002 -2 - 1674 Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1) - none - gi|15609722 fig|83332.1.peg.2588 CDS NC_000962 2914009 2912681 -1 - 1329 Protein-export membrane protein SecF (TC 3.A.5.1.1) - none - gi|15609723 fig|83332.1.peg.2589 CDS NC_000962 2915734 2914013 -1 - 1722 Protein-export membrane protein SecD (TC 3.A.5.1.1) - none - gi|15609724 fig|83332.1.peg.2590 CDS NC_000962 2916191 2915844 -2 - 348 Preprotein translocase subunit YajC (TC 3.A.5.1.1) - none - gi|15609725 fig|83332.1.peg.2591 CDS NC_000962 2916358 2917707 1 + 1350 Gamma-aminobutyrate:alpha-ketoglutarate aminotransferase (EC 2.6.1.19) - none - gi|15609726 fig|83332.1.peg.2592 CDS NC_000962 2917869 2921375 3 + 3507 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) Biotin biosynthesis;
Biotin synthesis cluster;
Fatty acid metabolism cluster gi|15609727 fig|83332.1.peg.2593 CDS NC_000962 2921549 2923180 2 + 1632 PE-PGRS virulence associated protein - none - gi|15609728 fig|83332.1.peg.2594 CDS NC_000962 2924231 2923197 -2 - 1035 Holliday junction DNA helicase RuvB RuvABC plus a hypothetical gi|15609729 fig|83332.1.peg.2595 CDS NC_000962 2924818 2924228 -1 - 591 Holliday junction DNA helicase RuvA RuvABC plus a hypothetical gi|15609730 fig|83332.1.peg.2596 CDS NC_000962 2925381 2924815 -3 - 567 Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) RuvABC plus a hypothetical gi|15609731 fig|83332.1.peg.2597 CDS NC_000962 2925490 2925735 1 + 246 hypothetical protein Rv2595 - none - gi|15609732 fig|83332.1.peg.2598 CDS NC_000962 2925732 2926136 3 + 405 Toxin 1, PIN domain Toxin-Antitoxin MT1 gi|15609733 fig|83332.1.peg.2599 CDS NC_000962 2926353 2926973 3 + 621 Possible membrane protein - none - gi|15609734 fig|83332.1.peg.2600 CDS NC_000962 2926984 2927478 1 + 495 hypothetical protein Rv2598 - none - gi|15609735 fig|83332.1.peg.2601 CDS NC_000962 2927475 2927906 3 + 432 Possible membrane protein - none - gi|15609736 fig|83332.1.peg.2602 CDS NC_000962 2927988 2928389 3 + 402 Possible membrane protein - none - gi|15609737 fig|83332.1.peg.2603 CDS NC_000962 2928386 2929957 2 + 1572 Spermidine synthase (EC 2.5.1.16) Polyamine Metabolism gi|15609738 fig|83332.1.peg.2604 CDS NC_000962 2930342 2930782 2 + 441 Toxin 1, PIN domain Toxin-Antitoxin MT1 gi|15609739 fig|83332.1.peg.2605 CDS NC_000962 2931558 2930803 -3 - 756 FIG000859: hypothetical protein YebC CBSS-1806.1.peg.1285;
Riboflavin, FMN and FAD metabolism in plants;
RuvABC plus a hypothetical gi|15609740 fig|83332.1.peg.2606 CDS NC_000962 2932287 2931691 -3 - 597 Pyridoxine biosynthesis glutamine amidotransferase, glutaminase subunit (EC 2.4.2.-) CBSS-1806.1.peg.1285;
Pyridoxin (Vitamin B6) Biosynthesis gi|15609741 fig|83332.1.peg.2607 CDS NC_000962 2933140 2932295 -1 - 846 Acyl-CoA thioesterase II (EC 3.1.2.-) Acyl-CoA thioesterase II;
CBSS-1806.1.peg.1285 gi|15609742 fig|83332.1.peg.2608 CDS NC_000962 2934068 2933169 -2 - 900 Pyridoxine biosynthesis glutamine amidotransferase, synthase subunit (EC 2.4.2.-) CBSS-1806.1.peg.1285;
Pyridoxin (Vitamin B6) Biosynthesis gi|15609743 fig|83332.1.peg.2609 CDS NC_000962 2934196 2934870 1 + 675 Pyridoxamine 5'-phosphate oxidase (EC 1.4.3.5) Pyridoxin (Vitamin B6) Biosynthesis gi|15609744 fig|83332.1.peg.2610 CDS NC_000962 2935044 2936786 3 + 1743 PPE family protein CBSS-164757.7.peg.5020 gi|15609745 fig|83332.1.peg.2611 CDS NC_000962 2937863 2936808 -2 - 1056 FIG019327: Probable conserved membrane protein - none - gi|15609746 fig|83332.1.peg.2612 CDS NC_000962 2938999 2937863 -1 - 1137 Phosphatidylinositol alpha-mannosyltransferase (EC 2.4.1.57) CBSS-1806.1.peg.1285 gi|15609747 fig|83332.1.peg.2613 CDS NC_000962 2939960 2939010 -2 - 951 Lauroyl/myristoyl acyltransferase involved in lipid A biosynthesis (Lauroyl/myristoyl acyltransferase) CBSS-1806.1.peg.1285 gi|15609748 fig|83332.1.peg.2614 CDS NC_000962 2940610 2939957 -1 - 654 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (EC 2.7.8.5) CBSS-1806.1.peg.1285;
Glycerolipid and Glycerophospholipid Metabolism in Bacteria gi|15609749 fig|83332.1.peg.2615 CDS NC_000962 2941194 2940607 -3 - 588 FIG049476: HIT family protein CBSS-1806.1.peg.1285 gi|15609750 fig|83332.1.peg.2616 CDS NC_000962 2943265 2941187 -1 - 2079 Threonyl-tRNA synthetase (EC 6.1.1.3) CBSS-1806.1.peg.1285;
tRNA aminoacylation, Thr gi|15609751 fig|83332.1.peg.2617 CDS NC_000962 2944983 2943598 -3 - 1386 (MTCY01A10.19), len: 461 aa. Member of M. tuberculosis gly-, ala-, asn-rich PE protein family, pgrs subfamily - none - gi|15609752 fig|83332.1.peg.2618 CDS NC_000962 2945328 2945828 3 + 501 FIG037376: hypothetical protein - none - gi|15609753 fig|83332.1.peg.2619 CDS NC_000962 2946285 2945845 -3 - 441 Possible membrane protein - none - gi|15609754 fig|83332.1.peg.2620 CDS NC_000962 2946432 2947109 3 + 678 Putative transcriptional regulatory protein - none - gi|15609755 fig|83332.1.peg.2621 CDS NC_000962 2947447 2947094 -1 - 354 hypothetical protein Rv2619c - none - gi|15609756 fig|83332.1.peg.2622 CDS NC_000962 2947885 2947460 -1 - 426 Possible membrane protein - none - gi|15609757 fig|83332.1.peg.2623 CDS NC_000962 2948556 2947882 -3 - 675 Putative transcriptional regulatory protein - none - gi|15609758 fig|83332.1.peg.2624 CDS NC_000962 2948634 2949455 3 + 822 Possible methyltransferase (Methylase) - none - gi|15609759 fig|83332.1.peg.2625 CDS NC_000962 2949591 2950484 3 + 894 Universal stress protein family Universal stress protein family gi|15609760 fig|83332.1.peg.2626 CDS NC_000962 2951305 2950487 -1 - 819 Universal stress protein family Universal stress protein family gi|15609761 fig|83332.1.peg.2627 CDS NC_000962 2952501 2951320 -3 - 1182 Probable conserved transmembrane alanine and leucine rich protein - none - gi|15609762 fig|83332.1.peg.2628 CDS NC_000962 2952991 2952560 -1 - 432 CBS domain protein - none - gi|15609763 fig|83332.1.peg.2629 CDS NC_000962 2954746 2953505 -1 - 1242 hypothetical protein Rv2627c - none - gi|15609764 fig|83332.1.peg.2630 CDS NC_000962 2955056 2955418 2 + 363 hypothetical protein Rv2628 - none - gi|15609765 fig|83332.1.peg.2631 CDS NC_000962 2955765 2956889 3 + 1125 hypothetical protein Rv2629 - none - gi|15609766 fig|83332.1.peg.2632 CDS NC_000962 2956891 2957430 1 + 540 Archease Archease gi|15609767 fig|83332.1.peg.2633 CDS NC_000962 2957546 2958343 2 + 798 RNA-2',3'-PO4:RNA-5'-OH ligase Inteins;
RNA 3'-terminal phosphate cyclase;
tRNA splicing gi|15609768 fig|83332.1.peg.2634 CDS NC_000962 2959187 2958906 -2 - 282 hypothetical protein - none - gi|15609769 fig|83332.1.peg.2635 CDS NC_000962 2959817 2959332 -2 - 486 hypothetical protein - none - gi|15609770 fig|83332.1.peg.2636 CDS NC_000962 2962438 2960102 -1 - 2337 PE family protein - none - gi|15609771 fig|83332.1.peg.2637 CDS NC_000962 2962467 2962709 3 + 243 hypothetical protein - none - gi|15609772 fig|83332.1.peg.2638 CDS NC_000962 2962710 2963387 3 + 678 Putative O-phosphotransferase (EC 2.7.1.-) - none - gi|15609773 fig|83332.1.peg.2639 CDS NC_000962 2963583 2964239 3 + 657 DedA protein DedA family of inner membrane proteins;
Uptake of selenate and selenite gi|15609774 fig|83332.1.peg.2640 CDS NC_000962 2964402 2964848 3 + 447 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV - none - gi|15609775 fig|83332.1.peg.2641 CDS NC_000962 2965355 2965023 -2 - 333 FIG035174: membrane protein - none - gi|15609776 fig|83332.1.peg.2642 CDS NC_000962 2965834 2965475 -1 - 360 Transcriptional regulator, ArsR family - none - gi|15609777 fig|83332.1.peg.2643 CDS NC_000962 2965936 2966394 1 + 459 Lactoylglutathione lyase (EC 4.4.1.5) @ Cadmium-induced protein CadI - none - gi|15609778 fig|83332.1.peg.2644 CDS NC_000962 2966530 2966910 1 + 381 Arsenical resistance operon repressor Arsenic resistance gi|15609779 fig|83332.1.peg.2645 CDS NC_000962 2966907 2968403 3 + 1497 Arsenical-resistance protein ACR3 / Arsenate reductase (EC 1.20.4.1) Anaerobic respiratory reductases;
Arsenic resistance;
Arsenic resistance;
Transcription repair cluster gi|15609780 fig|83332.1.peg.2646 CDS NC_000962 2968847 2968530 -2 - 318 hypothetical protein - none - gi|15609781 fig|83332.1.peg.2647 CDS NC_000962 2970120 2970551 3 + 432 hypothetical protein - none - gi|15609782 fig|83332.1.peg.2648 CDS NC_000962 2970548 2971546 2 + 999 phage integrase family protein - none - gi|15609783 fig|83332.1.peg.2649 CDS NC_000962 2971656 2972024 3 + 369 FIG00822089: hypothetical protein - none - gi|15609784 fig|83332.1.peg.2650 CDS NC_000962 2972157 2972483 3 + 327 Mobile element protein - none - gi|15609785 fig|83332.1.peg.2651 CDS NC_000962 2972432 2973418 2 + 987 Mobile element protein - none - gi|15609786 fig|83332.1.peg.2652 CDS NC_000962 2975231 2973792 -2 - 1440 Phage major capsid protein Phage capsid proteins gi|15609787 fig|83332.1.peg.2653 CDS NC_000962 2975772 2975239 -3 - 534 PhiRv2 phage prohead protease, HK97 family - none - gi|15609788 fig|83332.1.peg.2654 CDS NC_000962 2976551 2975925 -2 - 627 PhiRv2 phage terminase, small subunit, P27 family - none - gi|15609789 fig|83332.1.peg.2655 CDS NC_000962 2976906 2976583 -3 - 324 FIG040773: hypothetical phiRv2 prophage protein - none - gi|15609790 fig|83332.1.peg.2656 CDS NC_000962 2977231 2976986 -1 - 246 FIG050287: hypothetical phiRv2 prophage protein - none - gi|15609791 fig|83332.1.peg.2657 CDS NC_000962 2978655 2977228 -3 - 1428 hypothetical protein Rv2655c - none - gi|15609792 fig|83332.1.peg.2658 CDS NC_000962 2979049 2978657 -1 - 393 hypothetical protein Rv2656c - none - gi|15609793 fig|83332.1.peg.2659 CDS NC_000962 2979306 2979046 -3 - 261 hypothetical protein Rv2657c - none - gi|15609794 fig|83332.1.peg.2660 CDS NC_000962 2979685 2979323 -1 - 363 hypothetical protein Rv2658c - none - gi|15609795 fig|83332.1.peg.2661 CDS NC_000962 2980815 2979688 -3 - 1128 hypothetical protein Rv2659c - none - gi|15609796 fig|83332.1.peg.2662 CDS NC_000962 2981187 2980960 -3 - 228 hypothetical protein Rv2660c - none - gi|15609797 fig|83332.1.peg.2663 CDS NC_000962 2981573 2981184 -2 - 390 hypothetical protein Rv2661c - none - gi|15609798 fig|83332.1.peg.2664 CDS NC_000962 2981479 2981751 1 + 273 hypothetical protein Rv2662 - none - gi|15609799 fig|83332.1.peg.2665 CDS NC_000962 2981850 2982083 3 + 234 hypothetical protein Rv2663 - none - gi|15609800 fig|83332.1.peg.2666 CDS NC_000962 2982094 2982348 1 + 255 hypothetical protein Rv2664 - none - gi|15609801 fig|83332.1.peg.2667 CDS NC_000962 2982696 2982977 3 + 282 FIG00822109: hypothetical protein - none - gi|15609802 fig|83332.1.peg.2668 CDS NC_000962 2983068 2983871 3 + 804 Mobile element protein - none - gi|15609803 fig|83332.1.peg.2669 CDS NC_000962 2983893 2984651 3 + 759 Probable ATP-dependent Clp protease ATP-binding subunit - none - gi|15609804 fig|83332.1.peg.2670 CDS NC_000962 2984730 2985251 3 + 522 Putative alanine and valine rich exported protein - none - gi|15609805 fig|83332.1.peg.2671 CDS NC_000962 2985280 2985750 1 + 471 Uncharacterized N-acetyltransferase (EC 2.3.1.-) - none - gi|15609806 fig|83332.1.peg.2672 CDS NC_000962 2986837 2985728 -1 - 1110 AFG1 family ATPase - none - gi|15609807 fig|83332.1.peg.2673 CDS NC_000962 2986836 2987612 3 + 777 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193) homolog - none - gi|15609808 fig|83332.1.peg.2674 CDS NC_000962 2987679 2989265 3 + 1587 Hypothetical secreted protease - none - gi|15609809 fig|83332.1.peg.2675 CDS NC_000962 2989288 2990589 1 + 1302 Putative membrane protein Q2 colocalized with Q - none - gi|15609810 fig|83332.1.peg.2676 CDS NC_000962 2990703 2991113 3 + 411 Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12) Peptide methionine sulfoxide reductase gi|15609811 fig|83332.1.peg.2677 CDS NC_000962 2991933 2991181 -3 - 753 Methyltransferase (EC 2.1.1.-) colocalized with Q - none - gi|15609812 fig|83332.1.peg.2678 CDS NC_000962 2992625 2991930 -2 - 696 Hemoprotein HemQ, essential component of heme biosynthetic pathway in Gram-positive bacteria Heme and Siroheme Biosynthesis gi|15609813 fig|83332.1.peg.2679 CDS NC_000962 2993989 2992715 -1 - 1275 Protoporphyrinogen IX oxidase, aerobic (EC 1.3.3.4) Heme and Siroheme Biosynthesis gi|15609814 fig|83332.1.peg.2680 CDS NC_000962 2995059 2993986 -3 - 1074 Uroporphyrinogen III decarboxylase (EC 4.1.1.37) Heme and Siroheme Biosynthesis gi|15609815 fig|83332.1.peg.2681 CDS NC_000962 2995112 2995942 2 + 831 Enoyl-CoA hydratase (EC 4.2.1.17) Acetyl-CoA fermentation to Butyrate;
Butanol Biosynthesis;
Fatty acid metabolism cluster;
Isoleucine degradation;
Polyhydroxybutyrate metabolism;
Valine degradation gi|15609816 fig|83332.1.peg.2682 CDS NC_000962 2996102 2996734 2 + 633 Uncharacterized protein Q1 colocalized with Q - none - gi|15609817 fig|83332.1.peg.2683 CDS NC_000962 2996736 2998052 3 + 1317 Ribonuclease D (EC 3.1.26.3) tRNA processing gi|15609818 fig|83332.1.peg.2684 CDS NC_000962 2999965 2998049 -1 - 1917 1-deoxy-D-xylulose 5-phosphate synthase (EC 2.2.1.7) Isoprenoid Biosynthesis;
Nonmevalonate Branch of Isoprenoid Biosynthesis;
Pyridoxin (Vitamin B6) Biosynthesis;
Thiamin biosynthesis gi|15609819 fig|83332.1.peg.2685 CDS NC_000962 3000109 3000606 1 + 498 FIG00822000: hypothetical protein - none - gi|15609820 fig|83332.1.peg.2686 CDS NC_000962 3000611 3001900 2 + 1290 Na+/H+ antiporter NhaD type - none - gi|15609821 fig|83332.1.peg.2687 CDS NC_000962 3001980 3003266 3 + 1287 Na+/H+ antiporter NhaD type - none - gi|15609822 fig|83332.1.peg.2688 CDS NC_000962 3004035 3003277 -3 - 759 Probable antibiotic-transport integral membrane leucine and alanine and valine rich protein ABC transporter - none - gi|15609823 fig|83332.1.peg.2689 CDS NC_000962 3004745 3004032 -2 - 714 PROBABLE ANTIBIOTIC-TRANSPORT INTEGRAL MEMBRANE LEUCINE AND VALINE RICH PROTEIN ABC TRANSPORTER - none - gi|15609824 fig|83332.1.peg.2690 CDS NC_000962 3005647 3004742 -1 - 906 PROBABLE ANTIBIOTIC-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER - none - gi|15609825 fig|83332.1.peg.2691 CDS NC_000962 3007059 3005842 -3 - 1218 23S rRNA (Uracil-5-) -methyltransferase RumA (EC 2.1.1.-) RNA methylation gi|15609826 fig|83332.1.peg.2692 CDS NC_000962 3009206 3007233 -2 - 1974 PROBABLE CONSERVED INTEGRAL MEMBRANE ALANINE AND VALINE AND LEUCINE RICH PROTEIN - none - gi|15609827 fig|83332.1.peg.2693 CDS NC_000962 3009341 3010024 2 + 684 Trk system potassium uptake protein TrkA Bacterial RNA-metabolizing Zn-dependent hydrolases;
Conserved gene cluster associated with Met-tRNA formyltransferase;
Glutathione-regulated potassium-efflux system and associated functions;
Potassium homeostasis gi|15609828 fig|83332.1.peg.2694 CDS NC_000962 3010021 3010683 1 + 663 Trk system potassium uptake protein TrkA Bacterial RNA-metabolizing Zn-dependent hydrolases;
Conserved gene cluster associated with Met-tRNA formyltransferase;
Glutathione-regulated potassium-efflux system and associated functions;
Potassium homeostasis gi|15609829 fig|83332.1.peg.2695 CDS NC_000962 3011365 3010694 -1 - 672 PROBABLE CONSERVED INTEGRAL MEMBRANE ALANINE AND LEUCINE RICH PROTEIN - none - gi|15609830 fig|83332.1.peg.2696 CDS NC_000962 3011764 3011396 -1 - 369 OB-fold nucleic acid binding protein - none - gi|15609831 fig|83332.1.peg.2697 CDS NC_000962 3011913 3012620 3 + 708 FIG00821557: hypothetical protein - none - gi|15609832 fig|83332.1.peg.2698 CDS NC_000962 3013605 3012826 -3 - 780 FIG00822685: hypothetical protein - none - gi|15609833 fig|83332.1.peg.2699 CDS NC_000962 3014144 3013680 -2 - 465 Deoxyuridine 5'-triphosphate nucleotidohydrolase (EC 3.6.1.23) Housecleaning nucleoside triphosphate pyrophosphatases;
Nudix proteins (nucleoside triphosphate hydrolases) gi|15609834 fig|83332.1.peg.2700 CDS NC_000962 3014170 3014655 1 + 486 Probable conserved alanine rich transmembrane protein - none - gi|15609835 fig|83332.1.peg.2701 CDS NC_000962 3014962 3014660 -1 - 303 hypothetical protein Rv2699c - none - gi|15609836 fig|83332.1.peg.2702 CDS NC_000962 3015200 3015850 2 + 651 Possible secreted alanine rich protein - none - gi|15609837 fig|83332.1.peg.2703 CDS NC_000962 3016732 3015860 -1 - 873 Inositol-1-monophosphatase (EC 3.1.3.25) - none - gi|15609838 fig|83332.1.peg.2704 CDS NC_000962 3016855 3017652 1 + 798 Polyphosphate glucokinase (EC 2.7.1.63) Glycolysis and Gluconeogenesis;
Polyphosphate gi|15609839 fig|83332.1.peg.2705 CDS NC_000962 3017832 3019418 3 + 1587 RNA polymerase sigma factor SigB Transcription initiation, bacterial sigma factors gi|15609840 fig|83332.1.peg.2706 CDS NC_000962 3019455 3019883 3 + 429 Putative translation initiation inhibitor, YjgF family - none - gi|15609841 fig|83332.1.peg.2707 CDS NC_000962 3020200 3019811 -1 - 390 Glutathione S-transferase domain protein Single-Rhodanese-domain proteins gi|15609842 fig|83332.1.peg.2708 CDS NC_000962 3020454 3020197 -3 - 258 hypothetical protein Rv2706c - none - gi|15609843 fig|83332.1.peg.2709 CDS NC_000962 3020570 3021544 2 + 975 Ribonuclease BN (EC 3.1.-.-) - none - gi|15609844 fig|83332.1.peg.2710 CDS NC_000962 3021793 3021545 -1 - 249 hypothetical protein Rv2708c - none - gi|15609845 fig|83332.1.peg.2711 CDS NC_000962 3021836 3022282 2 + 447 Possible membrane protein - none - gi|15609846 fig|83332.1.peg.2712 CDS NC_000962 3022458 3023429 3 + 972 RNA polymerase sigma factor SigB SigmaB stress responce regulation;
Transcription initiation, bacterial sigma factors gi|15609847 fig|83332.1.peg.2713 CDS NC_000962 3023562 3024254 3 + 693 Iron-dependent repressor IdeR/DtxR - none - gi|15609848 fig|83332.1.peg.2714 CDS NC_000962 3025325 3024267 -2 - 1059 hypothetical protein Rv2712c - none - gi|15609849 fig|83332.1.peg.2715 CDS NC_000962 3025438 3026844 1 + 1407 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) NAD and NADP cofactor biosynthesis global;
Phosphate metabolism gi|15609850 fig|83332.1.peg.2716 CDS NC_000962 3027062 3028036 2 + 975 FIG00821757: hypothetical protein - none - gi|15609851 fig|83332.1.peg.2717 CDS NC_000962 3028095 3029120 3 + 1026 Hydrolase, alpha/beta fold family - none - gi|15609852 fig|83332.1.peg.2718 CDS NC_000962 3029169 3029855 3 + 687 Phenazine biosynthesis protein PhzF like - none - gi|15609853 fig|83332.1.peg.2719 CDS NC_000962 3030358 3029864 -1 - 495 DUF1794 - none - gi|15609854 fig|83332.1.peg.2720 CDS NC_000962 3030874 3030410 -1 - 465 Ribonucleotide reductase transcriptional regulator NrdR Ribonucleotide reduction gi|15609855 fig|83332.1.peg.2721 CDS NC_000962 3031534 3031037 -1 - 498 hypothetical protein Rv2719c - none - gi|15609856 fig|83332.1.peg.2722 CDS NC_000962 3031842 3032495 3 + 654 SOS-response repressor and protease LexA (EC 3.4.21.88) DNA repair, bacterial gi|15609857 fig|83332.1.peg.2723 CDS NC_000962 3034616 3032517 -2 - 2100 Possible conserved transmembrane alanine and glycine rich protein - none - gi|15609858 fig|83332.1.peg.2724 CDS NC_000962 3034632 3034880 3 + 249 hypothetical protein Rv2722 - none - gi|15609859 fig|83332.1.peg.2725 CDS NC_000962 3034906 3036099 1 + 1194 Integral membrane protein TerC - none - gi|15609860 fig|83332.1.peg.2726 CDS NC_000962 3037288 3036128 -1 - 1161 Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.8.1) - none - gi|15609861 fig|83332.1.peg.2727 CDS NC_000962 3038911 3037424 -1 - 1488 GTP-binding protein HflX Hfl operon;
Universal GTPases gi|15609862 fig|83332.1.peg.2728 CDS NC_000962 3039797 3038928 -2 - 870 Diaminopimelate epimerase (EC 5.1.1.7) CBSS-84588.1.peg.1247;
Lysine Biosynthesis DAP Pathway;
Lysine Biosynthesis DAP Pathway, GJO scratch gi|15609863 fig|83332.1.peg.2729 CDS NC_000962 3040766 3039822 -2 - 945 tRNA dimethylallyltransferase (EC 2.5.1.75) tRNA modification Bacteria;
tRNA processing gi|15609864 fig|83332.1.peg.2730 CDS NC_000962 3041458 3040763 -1 - 696 FIG00820085: hypothetical protein - none - gi|15609865 fig|83332.1.peg.2731 CDS NC_000962 3042472 3041567 -1 - 906 Putative conserved alanine, valine and leucine rich integral membrane protein - none - gi|15609866 fig|83332.1.peg.2732 CDS NC_000962 3042539 3043015 2 + 477 FIG061213: hypothetical protein - none - gi|15609867 fig|83332.1.peg.2733 CDS NC_000962 3043023 3044375 3 + 1353 ATPase involved in DNA repair - none - gi|15609868 fig|83332.1.peg.2734 CDS NC_000962 3044986 3044372 -1 - 615 Possible membrane protein - none - gi|15609869 fig|83332.1.peg.2735 CDS NC_000962 3046521 3044983 -3 - 1539 tRNA-i(6)A37 methylthiotransferase Methylthiotransferases;
tRNA modification Bacteria;
tRNA processing gi|15609870 fig|83332.1.peg.2736 CDS NC_000962 3046818 3047672 3 + 855 Phage Gp37Gp68 protein - none - gi|15609871 fig|83332.1.peg.2737 CDS NC_000962 3048549 3047557 -3 - 993 FIG032330: hypothetical protein - none - gi|15609872 fig|83332.1.peg.2738 CDS NC_000962 3049083 3048564 -3 - 520 Regulatory protein RecX RecA and RecX gi|15609873 fig|83332.1.peg.2739 CDS NC_000962 3051421 3049049 -1 - 2373 RecA protein @ intein-containing DNA repair, bacterial;
DNA repair, bacterial RecFOR pathway;
Inteins;
RecA and RecX gi|15609874 fig|83332.1.peg.2740 CDS NC_000962 3052009 3051803 -1 - 207 hypothetical protein Rv2738c - none - gi|15609875 fig|83332.1.peg.2741 CDS NC_000962 3053186 3052020 -2 - 1167 Alanine rich transferase - none - gi|15609876 fig|83332.1.peg.2742 CDS NC_000962 3053230 3053679 1 + 450 hypothetical protein Rv2740 - none - gi|15609877 fig|83332.1.peg.2743 CDS NC_000962 3053911 3055488 1 + 1578 PE-PGRS FAMILY PROTEIN - none - gi|15609878 fig|83332.1.peg.2744 CDS NC_000962 3056345 3055512 -2 - 834 hypothetical protein Rv2742c - none - gi|15609879 fig|83332.1.peg.2745 CDS NC_000962 3057229 3056417 -1 - 813 Possible conserved membrane alanine rich protein - none - gi|15609880 fig|83332.1.peg.2746 CDS NC_000962 3058060 3057248 -1 - 813 Phage shock protein A (IM30) , suppresses sigma54-dependent transcription - none - gi|15609881 fig|83332.1.peg.2747 CDS NC_000962 3058528 3058190 -1 - 339 Hypothetical transcriptional regulatory protein - none - gi|15609882 fig|83332.1.peg.2748 CDS NC_000962 3059228 3058599 -2 - 630 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (EC 2.7.8.5) CBSS-1806.1.peg.1285;
Glycerolipid and Glycerophospholipid Metabolism in Bacteria gi|15609883 fig|83332.1.peg.2749 CDS NC_000962 3059259 3059783 3 + 525 N-acetylglutamate synthase (EC 2.3.1.1) Arginine Biosynthesis extended gi|15609884 fig|83332.1.peg.2750 CDS NC_000962 3062503 3059852 -1 - 2652 Cell division protein FtsK Bacterial Cell Division;
Bacterial Cytoskeleton;
Bacterial RNA-metabolizing Zn-dependent hydrolases gi|15609885 fig|83332.1.peg.2751 CDS NC_000962 3062502 3062816 3 + 315 Antibiotic biosynthesis monooxygenase - none - gi|15609886 fig|83332.1.peg.2752 CDS NC_000962 3062813 3063631 2 + 819 Dehydrogenase - none - gi|15609887 fig|83332.1.peg.2753 CDS NC_000962 3063635 3064525 2 + 891 O-Methyltransferase involved in polyketide biosynthesis - none - gi|15609888 fig|83332.1.peg.2754 CDS NC_000962 3066188 3064512 -2 - 1677 Ribonuclease J2 (endoribonuclease in RNA processing) Bacterial RNA-metabolizing Zn-dependent hydrolases;
Ribonucleases in Bacillus gi|15609889 fig|83332.1.peg.2755 CDS NC_000962 3067121 3066219 -2 - 903 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) Lysine Biosynthesis DAP Pathway;
Lysine Biosynthesis DAP Pathway, GJO scratch gi|15609890 fig|83332.1.peg.2756 CDS NC_000962 3067942 3067190 -1 - 753 Thymidylate synthase thyX (EC 2.1.1.-) Folate Biosynthesis gi|15609891 fig|83332.1.peg.2757 CDS NC_000962 3068461 3068186 -1 - 276 Possible type I restriction/modification system specificity determinant hsdS' - none - gi|15609892 fig|83332.1.peg.2758 CDS NC_000962 3070080 3068458 -3 - 1623 Type I restriction-modification system, DNA-methyltransferase subunit M (EC 2.1.1.72) Restriction-Modification System gi|15609893 fig|83332.1.peg.2759 CDS NC_000962 3070583 3070167 -2 - 417 Toxin 1, PIN domain Toxin-Antitoxin MT1 gi|15609894 fig|83332.1.peg.2760 CDS NC_000962 3070846 3070580 -1 - 267 hypothetical protein Rv2758c - none - gi|15609895 fig|83332.1.peg.2761 CDS NC_000962 3071267 3070872 -2 - 396 Toxin 1, PIN domain Toxin-Antitoxin MT1 gi|15609896 fig|83332.1.peg.2762 CDS NC_000962 3071533 3071264 -1 - 270 hypothetical protein Rv2760c - none - gi|15609897 fig|83332.1.peg.2763 CDS NC_000962 3072637 3071543 -1 - 1095 Type I restriction-modification system, specificity subunit S (EC 3.1.21.3) - none - gi|15609898 fig|83332.1.peg.2764 CDS NC_000962 3073053 3072634 -3 - 420 FIG074102: hypothetical protein - none - gi|15609899 fig|83332.1.peg.2765 CDS NC_000962 3073606 3073127 -1 - 480 Dihydrofolate reductase (EC 1.5.1.3) 5-FCL-like protein;
Folate Biosynthesis gi|15609900 fig|83332.1.peg.2766 CDS NC_000962 3074468 3073677 -2 - 792 Thymidylate synthase (EC 2.1.1.45) Folate Biosynthesis;
pyrimidine conversions gi|15609901 fig|83332.1.peg.2767 CDS NC_000962 3074633 3075370 2 + 738 Dienelactone hydrolase family - none - gi|15609902 fig|83332.1.peg.2768 CDS NC_000962 3076367 3075585 -2 - 783 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) - none - gi|15609903 fig|83332.1.peg.2769 CDS NC_000962 3076717 3076364 -1 - 354 hypothetical protein Rv2767c - none - gi|15609904 fig|83332.1.peg.2770 CDS NC_000962 3078075 3076891 -3 - 1185 PPE family protein CBSS-164757.7.peg.5020 gi|15609905 fig|83332.1.peg.2771 CDS NC_000962 3078982 3078155 -1 - 828 PE family protein - none - gi|15609906 fig|83332.1.peg.2772 CDS NC_000962 3080514 3079306 -3 - 1209 PPE family protein CBSS-164757.7.peg.5020 gi|15609907 fig|83332.1.peg.2773 CDS NC_000962 3081030 3080578 -3 - 453 Multimeric flavodoxin WrbA - none - gi|15609908 fig|83332.1.peg.2774 CDS NC_000962 3081589 3081116 -1 - 474 FIG00820747: hypothetical protein - none - gi|15609909 fig|83332.1.peg.2775 CDS NC_000962 3082338 3081601 -3 - 738 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) Lysine Biosynthesis DAP Pathway;
Lysine Biosynthesis DAP Pathway, GJO scratch gi|15609910 fig|83332.1.peg.2776 CDS NC_000962 3082753 3082349 -1 - 405 hypothetical protein Rv2774c - none - gi|15609911 fig|83332.1.peg.2777 CDS NC_000962 3082906 3083367 1 + 462 Acetyltransferase, GNAT family - none - gi|15609912 fig|83332.1.peg.2778 CDS NC_000962 3084300 3083371 -3 - 930 Vanillate O-demethylase oxidoreductase (EC 1.14.13.-) Anaerobic respiratory reductases gi|15609913 fig|83332.1.peg.2779 CDS NC_000962 3085552 3084482 -1 - 1071 FF domain protein - none - gi|15609914 fig|83332.1.peg.2780 CDS NC_000962 3086180 3085710 -2 - 471 hypothetical protein Rv2778c - none - gi|15609915 fig|83332.1.peg.2781 CDS NC_000962 3086727 3086212 -3 - 516 Transcriptional regulator, AsnC family - none - gi|15609916 fig|83332.1.peg.2782 CDS NC_000962 3086817 3087932 3 + 1116 Alanine dehydrogenase (EC 1.4.1.1) Pyruvate Alanine Serine Interconversions gi|15609917 fig|83332.1.peg.2783 CDS NC_000962 3088981 3087947 -1 - 1035 2-nitropropane dioxygenase (EC 1.13.11.32) - none - gi|15609918 fig|83332.1.peg.2784 CDS NC_000962 3090358 3089042 -1 - 1317 FIG007959: peptidase, M16 family CBSS-1806.1.peg.3045;
CBSS-350688.3.peg.1509 gi|15609919 fig|83332.1.peg.2785 CDS NC_000962 3092594 3090336 -2 - 2259 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) Bacterial RNA-metabolizing Zn-dependent hydrolases;
CBSS-1806.1.peg.3045;
CBSS-350688.3.peg.1509 gi|15609920 fig|83332.1.peg.2786 CDS NC_000962 3093463 3092948 -1 - 516 Lipoprotein LppU - none - gi|15609921 fig|83332.1.peg.2787 CDS NC_000962 3093745 3093476 -1 - 270 SSU ribosomal protein S15p (S13e) CBSS-350688.3.peg.1509;
Ribosome SSU bacterial gi|15609922 fig|83332.1.peg.2788 CDS NC_000962 3094897 3093902 -1 - 996 Riboflavin kinase (EC 2.7.1.26) / FMN adenylyltransferase (EC 2.7.7.2) CBSS-350688.3.peg.1509;
CBSS-350688.3.peg.1509;
Glutaredoxins;
Riboflavin, FMN and FAD metabolism;
Riboflavin, FMN and FAD metabolism;
Riboflavin, FMN and FAD metabolism in plants;
Riboflavin, FMN and FAD metabolism in plants;
dNTP triphosphohydrolase protein family;
riboflavin to FAD;
riboflavin to FAD gi|15609923 fig|83332.1.peg.2789 CDS NC_000962 3095108 3096871 2 + 1764 hypothetical protein Rv2787 - none - gi|15609924 fig|83332.1.peg.2790 CDS NC_000962 3096956 3097642 2 + 687 Mn-dependent transcriptional regulator MntR - none - gi|15609925 fig|83332.1.peg.2791 CDS NC_000962 3098935 3097703 -1 - 1233 Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.8.1) Isoleucine degradation gi|15609926 fig|83332.1.peg.2792 CDS NC_000962 3100166 3098961 -2 - 1206 (MTV002.55c), len: 401 aa. ltp1, probable lipid-transfer protein, highly similar to many eukaryotic sterol-carrier proteins eg. NLTP_RAT P11915 nonspecific lipid-transfer protein precursor (sterol carrier protein) (547 aa), fasta scores; opt: 1696 z-score: 2359.0 E(): 0, 63.2% identity in 394 aa overlap. Contains PS00098 Thiolases acyl-enzyme intermediate signature and PS00737 Thiolases signature 2. Also similar to other M. tuberculosis proteins eg. MTCY01B2.19c (35.8% identity in 413 aa overlap) - none - gi|15609927 fig|83332.1.peg.2793 CDS NC_000962 3101578 3100199 -1 - 1380 Mobile element protein - none - gi|15609928 fig|83332.1.peg.2794 CDS NC_000962 3102159 3101578 -3 - 582 Possible resolvase - none - gi|15609929 fig|83332.1.peg.2795 CDS NC_000962 3103257 3102361 -3 - 897 tRNA pseudouridine synthase B (EC 4.2.1.70) ## tRNA Psi55 CBSS-138119.3.peg.2719;
CBSS-350688.3.peg.1509;
RNA pseudouridine syntheses;
Riboflavin, FMN and FAD metabolism in plants;
tRNA modification Bacteria;
tRNA processing gi|15609930 fig|83332.1.peg.2796 CDS NC_000962 3103937 3103254 -2 - 684 4'-phosphopantetheinyl transferase EntD (EC 2.7.8.-) - none - gi|15609931 fig|83332.1.peg.2797 CDS NC_000962 3104908 3103934 -1 - 975 Metallophosphoesterase, SimX4 hydrolase - none - gi|15609932 fig|83332.1.peg.2798 CDS NC_000962 3105616 3105053 -1 - 564 PROBABLE CONSERVED LIPOPROTEIN LPPV - none - gi|15609933 fig|83332.1.peg.2799 CDS NC_000962 3107304 3105616 -3 - 1689 FIG00822807: hypothetical protein - none - gi|15609934 fig|83332.1.peg.2800 CDS NC_000962 3107634 3107308 -3 - 327 hypothetical protein Rv2798c - none - gi|15609935 fig|83332.1.peg.2801 CDS NC_000962 3107765 3108394 2 + 630 Possible membrane protein - none - gi|15609936 fig|83332.1.peg.2802 CDS NC_000962 3108413 3110062 2 + 1650 Possible hydrolase - none - gi|15609937 fig|83332.1.peg.2803 CDS NC_000962 3110520 3110164 -3 - 357 Programmed cell death toxin YdcE MazEF toxin-antitoxing (programmed cell death) system;
Phd-Doc, YdcE-YdcD toxin-antitoxin (programmed cell death) systems gi|15609938 fig|83332.1.peg.2804 CDS NC_000962 3111820 3110777 -1 - 1044 FIG00823567: hypothetical protein - none - gi|15609939 fig|83332.1.peg.2805 CDS NC_000962 3112283 3111834 -2 - 450 hypothetical protein Rv2803c - none - gi|15609940 fig|83332.1.peg.2806 CDS NC_000962 3113091 3112462 -3 - 630 hypothetical protein Rv2804c - none - gi|15609941 fig|83332.1.peg.2807 CDS NC_000962 3112864 3113268 1 + 405 FIG00821656: hypothetical protein - none - gi|15609942 fig|83332.1.peg.2808 CDS NC_000962 3113265 3113456 3 + 192 Possible membrane protein - none - gi|15609943 fig|83332.1.peg.2809 CDS NC_000962 3113655 3114809 3 + 1155 hypothetical protein Rv2807 - none - gi|15609944 fig|83332.1.peg.2810 CDS NC_000962 3115043 3115300 2 + 258 hypothetical protein - none - gi|15609945 fig|83332.1.peg.2811 CDS NC_000962 3115405 3115716 1 + 312 hypothetical protein Rv2809 - none - gi|15609946 fig|83332.1.peg.2812 CDS NC_000962 3116139 3115738 -3 - 402 hypothetical protein Rv2810c - none - gi|15609947 fig|83332.1.peg.2813 CDS NC_000962 3116136 3116744 3 + 609 hypothetical protein Rv2811 - none - gi|15609948 fig|83332.1.peg.2814 CDS NC_000962 3116815 3118224 1 + 1410 Mobile element protein - none - gi|15609949 fig|83332.1.peg.2815 CDS NC_000962 3118221 3119033 3 + 813 Type II secretory pathway, component ExeA - none - gi|15609950 fig|83332.1.peg.2816 CDS NC_000962 3121501 3120563 -1 - 939 Mobile element protein - none - gi|15609951 fig|83332.1.peg.2817 CDS NC_000962 3121824 3121498 -3 - 327 Mobile element protein - none - gi|15609952 fig|83332.1.peg.2818 CDS NC_000962 3123963 3123622 -3 - 342 CRISPR-associated protein Cas2 - none - gi|15609953 fig|83332.1.peg.2819 CDS NC_000962 3124980 3123964 -3 - 1017 CRISPR-associated protein Cas1 CRISPRs gi|15609954 fig|83332.1.peg.2820 CDS NC_000962 3126141 3124993 -3 - 1149 CRISPR-associated protein Csm6 CRISPR-associated cluster gi|15609955 fig|83332.1.peg.2821 CDS NC_000962 3127364 3126237 -2 - 1128 CRISPR-associated protein, Csm5 family CRISPR-associated cluster;
CRISPRs gi|15609956 fig|83332.1.peg.2822 CDS NC_000962 3128269 3127361 -1 - 909 CRISPR-associated RAMP protein, Csm4 family CRISPR-associated cluster;
CRISPRs gi|15609957 fig|83332.1.peg.2823 CDS NC_000962 3128960 3128250 -2 - 711 CRISPR-associated RAMP Csm3 CRISPR-associated cluster;
CRISPRs gi|15609958 fig|83332.1.peg.2824 CDS NC_000962 3129344 3128970 -2 - 375 CRISPR-associated protein, Csm2 family CRISPR-associated cluster;
CRISPRs gi|15609959 fig|83332.1.peg.2825 CDS NC_000962 3131770 3129341 -1 - 2430 CRISPR-associated protein, Csm1 family CRISPR-associated cluster;
CRISPRs gi|15609960 fig|83332.1.peg.2826 CDS NC_000962 3132711 3131767 -3 - 945 CRISPR repeat RNA endoribonuclease Cas6 CRISPRs gi|15609961 fig|83332.1.peg.2827 CDS NC_000962 3133536 3132889 -3 - 648 FIG00820705: hypothetical protein - none - gi|15609962 fig|83332.1.peg.2828 CDS NC_000962 3134590 3133706 -1 - 885 hypothetical protein Rv2826c - none - gi|15609963 fig|83332.1.peg.2829 CDS NC_000962 3135480 3134593 -3 - 888 FIG00820907: hypothetical protein - none - gi|15609964 fig|83332.1.peg.2830 CDS NC_000962 3136330 3135785 -1 - 546 FIG00820705: hypothetical protein - none - gi|15609965 fig|83332.1.peg.2831 CDS NC_000962 3137009 3136617 -2 - 393 hypothetical protein - none - gi|15609966 fig|83332.1.peg.2832 CDS NC_000962 3137221 3137006 -1 - 216 hypothetical protein - none - gi|15609967 fig|83332.1.peg.2833 CDS NC_000962 3137268 3138017 3 + 750 Enoyl-CoA hydratase (EC 4.2.1.17) Acetyl-CoA fermentation to Butyrate;
Fatty acid metabolism cluster gi|15609968 fig|83332.1.peg.2834 CDS NC_000962 3139178 3138096 -2 - 1083 Glycerol-3-phosphate ABC transporter, ATP-binding protein UgpC (TC 3.A.1.1.3) Glycerol and Glycerol-3-phosphate Uptake and Utilization gi|15609969 fig|83332.1.peg.2835 CDS NC_000962 3140481 3139171 -3 - 1311 Glycerol-3-phosphate ABC transporter, periplasmic glycerol-3-phosphate-binding protein (TC 3.A.1.1.3) Glycerol and Glycerol-3-phosphate Uptake and Utilization gi|15609970 fig|83332.1.peg.2836 CDS NC_000962 3141311 3140484 -2 - 828 Glycerol-3-phosphate ABC transporter, permease protein UgpE (TC 3.A.1.1.3) Glycerol and Glycerol-3-phosphate Uptake and Utilization gi|15609971 fig|83332.1.peg.2837 CDS NC_000962 3142219 3141308 -1 - 912 Glycerol-3-phosphate ABC transporter, permease protein UgpA (TC 3.A.1.1.3) Glycerol and Glycerol-3-phosphate Uptake and Utilization gi|15609972 fig|83332.1.peg.2838 CDS NC_000962 3143625 3142306 -3 - 1320 putative DNA-damage-inducible protein F - none - gi|15609973 fig|83332.1.peg.2839 CDS NC_000962 3144642 3143632 -3 - 1011 FIG146085: 3'-to-5' oligoribonuclease A, Bacillus type CBSS-138119.3.peg.2719;
RNA processing and degradation, bacterial gi|15609974 fig|83332.1.peg.2840 CDS NC_000962 3145168 3144617 -1 - 552 Ribosome-binding factor A CBSS-138119.3.peg.2719;
CBSS-350688.3.peg.1509;
NusA-TFII Cluster;
RNA processing and degradation, bacterial;
Translation initiation factors bacterial gi|15609975 fig|83332.1.peg.2841 CDS NC_000962 3147870 3145168 -3 - 2703 Translation initiation factor 2 CBSS-138119.3.peg.2719;
CBSS-350688.3.peg.1509;
Inteins;
NusA-TFII Cluster;
Translation initiation factors bacterial;
Universal GTPases gi|15609976 fig|83332.1.peg.2842 CDS NC_000962 3148255 3147956 -1 - 300 COG2740: Predicted nucleic-acid-binding protein implicated in transcription termination CBSS-350688.3.peg.1509;
NusA-TFII Cluster;
Transcription factors bacterial gi|15609977 fig|83332.1.peg.2843 CDS NC_000962 3149425 3148382 -1 - 1044 Transcription termination protein NusA CBSS-350688.3.peg.1509;
NusA-TFII Cluster;
Transcription factors bacterial gi|15609978 fig|83332.1.peg.2844 CDS NC_000962 3149973 3149422 -3 - 552 FIG000325: clustered with transcription termination protein NusA CBSS-350688.3.peg.1509;
NusA-TFII Cluster;
Transcription factors bacterial gi|15609979 fig|83332.1.peg.2845 CDS NC_000962 3150168 3150713 3 + 546 Probable conserved transmembrane alanine rich protein - none - gi|15609980 fig|83332.1.peg.2846 CDS NC_000962 3150710 3151198 2 + 489 FIG00820361: hypothetical protein - none - gi|15609981 fig|83332.1.peg.2847 CDS NC_000962 3152947 3151199 -1 - 1749 Prolyl-tRNA synthetase (EC 6.1.1.15), bacterial type tRNA aminoacylation, Pro gi|15609982 fig|83332.1.peg.2848 CDS NC_000962 3154628 3153036 -2 - 1593 EmrB/QacA family drug resistance transporter - none - gi|15609983 fig|83332.1.peg.2849 CDS NC_000962 3155868 3154651 -3 - 1218 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) Coenzyme B12 biosynthesis;
Heme and Siroheme Biosynthesis;
Heme and Siroheme Biosynthesis;
Heme and Siroheme Biosynthesis gi|15609984 fig|83332.1.peg.2850 CDS NC_000962 3157518 3156145 -3 - 1374 Cobyrinic acid A,C-diamide synthase Cobalamin synthesis;
Coenzyme B12 biosynthesis gi|15609985 fig|83332.1.peg.2851 CDS NC_000962 3158141 3157518 -2 - 624 Cob(I)alamin adenosyltransferase (EC 2.5.1.17) Cobalamin synthesis;
Coenzyme B12 biosynthesis gi|15609986 fig|83332.1.peg.2852 CDS NC_000962 3160051 3158162 -1 - 1890 ChlI component of cobalt chelatase involved in B12 biosynthesis / ChlD component of cobalt chelatase involved in B12 biosynthesis Coenzyme B12 biosynthesis;
Coenzyme B12 biosynthesis gi|15609987 fig|83332.1.peg.2853 CDS NC_000962 3160518 3160048 -3 - 471 ElaA protein Glutathione-regulated potassium-efflux system and associated functions;
cAMP signaling in bacteria gi|15609988 fig|83332.1.peg.2854 CDS NC_000962 3162058 3160577 -1 - 1482 Malate:quinone oxidoreductase (EC 1.1.5.4) TCA Cycle gi|15609989 fig|83332.1.peg.2855 CDS NC_000962 3162265 3164112 1 + 1848 PE family protein - none - gi|15609990 fig|83332.1.peg.2856 CDS NC_000962 3164149 3165189 1 + 1041 Lysophospholipase (EC 3.1.1.5) Glutathione analogs: mycothiol;
Triacylglycerol metabolism gi|15609991 fig|83332.1.peg.2857 CDS NC_000962 3165202 3166581 1 + 1380 NADPH-dependent mycothiol reductase Mtr Glutathione analogs: mycothiol gi|15609992 fig|83332.1.peg.2858 CDS NC_000962 3166681 3167799 1 + 1119 HoxN/HupN/NixA family nickel/cobalt transporter Transport of Nickel and Cobalt gi|15609993 fig|83332.1.peg.2859 CDS NC_000962 3169356 3168580 -3 - 777 Short-chain dehydrogenase/reductase in hypothetical Actinobacterial gene cluster CBSS-262316.1.peg.2929 gi|15609994 fig|83332.1.peg.2860 CDS NC_000962 3170720 3169353 -2 - 1368 Aldehyde dehydrogenase in hypothetical Actinobacterial gene cluster CBSS-262316.1.peg.2929 gi|15609995 fig|83332.1.peg.2861 CDS NC_000962 3171643 3170717 -1 - 927 COG2071: predicted glutamine amidotransferases in hypothetical Actinobacterial gene cluster CBSS-262316.1.peg.2929 gi|15609996 fig|83332.1.peg.2862 CDS NC_000962 3172997 3171624 -2 - 1374 Glutamine synthetase family protein in hypothetical Actinobacterial gene cluster CBSS-262316.1.peg.2929;
Glutamine, Glutamate, Aspartate and Asparagine Biosynthesis gi|15609997 fig|83332.1.peg.2863 CDS NC_000962 3174014 3173157 -2 - 858 Methionine aminopeptidase (EC 3.4.11.18) CBSS-312309.3.peg.1965;
Translation termination factors bacterial gi|15609998 fig|83332.1.peg.2864 CDS NC_000962 3174640 3174056 -1 - 585 FIG020268: hypothetical protein - none - gi|15609999 fig|83332.1.peg.2865 CDS NC_000962 3174989 3175369 2 + 381 Putative uncharacterized protein BCG_2885 - none - gi|15610000 fig|83332.1.peg.2866 CDS NC_000962 3177262 3175451 -1 - 1812 Cell division protein FtsI [Peptidoglycan synthetase] (EC 2.4.1.129) 16S rRNA modification within P site of ribosome;
Bacterial Cell Division;
Bacterial Cytoskeleton;
CBSS-83331.1.peg.3039;
Peptidoglycan Biosynthesis gi|15610001 fig|83332.1.peg.2867 CDS NC_000962 3177534 3177815 3 + 282 RelB/StbD replicon stabilization protein (antitoxin to RelE/StbE) Toxin-antitoxin replicon stabilization systems gi|15610002 fig|83332.1.peg.2868 CDS NC_000962 3177819 3178082 3 + 264 RelE/StbE replicon stabilization toxin Toxin-antitoxin replicon stabilization systems gi|15610003 fig|83332.1.peg.2869 CDS NC_000962 3179309 3178455 -2 - 855 GCN5-related N-acetyltransferase, FIGfam019367 CBSS-83331.1.peg.3039 gi|15610004 fig|83332.1.peg.2870 CDS NC_000962 3180528 3179365 -3 - 1164 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase (EC 1.17.7.1) CBSS-83331.1.peg.3039;
Isoprenoid Biosynthesis;
Nonmevalonate Branch of Isoprenoid Biosynthesis gi|15610005 fig|83332.1.peg.2871 CDS NC_000962 3181759 3180545 -1 - 1215 Intramembrane protease RasP/YluC, implicated in cell division based on FtsL cleavage CBSS-83331.1.peg.3039;
Periplasmic Stress Response gi|15610006 fig|83332.1.peg.2872 CDS NC_000962 3183077 3181767 -2 - 1311 1-deoxy-D-xylulose 5-phosphate reductoisomerase (EC 1.1.1.267) CBSS-83331.1.peg.3039;
Isoprenoid Biosynthesis;
Nonmevalonate Branch of Isoprenoid Biosynthesis gi|15610007 fig|83332.1.peg.2873 CDS NC_000962 3183135 3183392 3 + 258 hypothetical protein Rv2871 - none - gi|15610008 fig|83332.1.peg.2874 CDS NC_000962 3183379 3183822 1 + 444 Toxin 1, PIN domain Toxin-Antitoxin MT1 gi|15610009 fig|83332.1.peg.2875 CDS NC_000962 3183902 3184564 2 + 663 Cell surface lipoprotein Mpt83 - none - gi|15610010 fig|83332.1.peg.2876 CDS NC_000962 3184844 3186931 2 + 2088 Possible integral membrane c-type cytochrome biogenesis protein DipZ - none - gi|15610011 fig|83332.1.peg.2877 CDS NC_000962 3187027 3187608 1 + 582 Immunogenic protein Mpt70 - none - gi|15610012 fig|83332.1.peg.2878 CDS NC_000962 3187660 3187974 1 + 315 Possible membrane protein - none - gi|15610013 fig|83332.1.peg.2879 CDS NC_000962 3188868 3188005 -3 - 864 Mercury resistance probable Hg transport protein - none - gi|15610014 fig|83332.1.peg.2880 CDS NC_000962 3189394 3188873 -1 - 522 Soluble secreted antigen MPT53 precursor - none - gi|15610015 fig|83332.1.peg.2881 CDS NC_000962 3190149 3189580 -3 - 570 Ribosomal RNA large subunit methyltransferase N (EC 2.1.1.-) ## LSU rRNA m2A2503 Conserved gene cluster associated with Met-tRNA formyltransferase;
RNA methylation gi|15610016 fig|83332.1.peg.2882 CDS NC_000962 3190675 3189848 -1 - 828 Ribosomal RNA large subunit methyltransferase N (EC 2.1.1.-) Conserved gene cluster associated with Met-tRNA formyltransferase;
RNA methylation gi|15610017 fig|83332.1.peg.2883 CDS NC_000962 3191618 3190698 -2 - 921 Phosphatidate cytidylyltransferase (EC 2.7.7.41) Glycerolipid and Glycerophospholipid Metabolism in Bacteria gi|15610018 fig|83332.1.peg.2884 CDS NC_000962 3192198 3191641 -3 - 558 Ribosome recycling factor Ribosome recycling related cluster;
Translation termination factors bacterial gi|15610019 fig|83332.1.peg.2885 CDS NC_000962 3193155 3192370 -3 - 786 Uridine monophosphate kinase (EC 2.7.4.22) CBSS-312309.3.peg.1965;
Ribosome recycling related cluster gi|15610020 fig|83332.1.peg.2886 CDS NC_000962 3193390 3194148 1 + 759 Transcriptional regulatory protein glnR - none - gi|15610021 fig|83332.1.peg.2887 CDS NC_000962 3195545 3194163 -2 - 1383 Mobile element protein - none - gi|15610022 fig|83332.1.peg.2888 CDS NC_000962 3196429 3195542 -1 - 888 Resolvase - none - gi|15610023 fig|83332.1.peg.2889 CDS NC_000962 3196428 3196847 3 + 420 Transcriptional regulator, MarR family - none - gi|15610024 fig|83332.1.peg.2890 CDS NC_000962 3198282 3196861 -3 - 1422 Putative amidase amiC (EC 3.5.1.4) - none - gi|15610025 fig|83332.1.peg.2891 CDS NC_000962 3199104 3198289 -3 - 816 Translation elongation factor Ts CBSS-312309.3.peg.1965;
Ribosome recycling related cluster;
Translation elongation factors bacterial gi|15610026 fig|83332.1.peg.2892 CDS NC_000962 3199979 3199116 -2 - 864 SSU ribosomal protein S2p (SAe) CBSS-312309.3.peg.1965;
Ribosome SSU bacterial;
Ribosome recycling related cluster gi|15610027 fig|83332.1.peg.2893 CDS NC_000962 3200263 3201012 1 + 750 Membrane proteins related to metalloendopeptidases cAMP signaling in bacteria gi|15610028 fig|83332.1.peg.2894 CDS NC_000962 3202017 3200791 -3 - 1227 PPE family protein CBSS-164757.7.peg.5020 gi|15610029 fig|83332.1.peg.2895 CDS NC_000962 3202417 3203394 1 + 978 POSSIBLE OXIDOREDUCTASE (EC 1.-.-.-) - none - gi|15610030 fig|83332.1.peg.2896 CDS NC_000962 3204287 3203391 -2 - 897 Tyrosine recombinase XerC - none - gi|15610031 fig|83332.1.peg.2897 CDS NC_000962 3205229 3204378 -2 - 852 Iron utilization protein - none - gi|15610032 fig|83332.1.peg.2898 CDS NC_000962 3206431 3205262 -1 - 1170 Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake Conserved gene cluster associated with Met-tRNA formyltransferase;
YrdC-YciO-Sua5 protein family gi|15610033 fig|83332.1.peg.2899 CDS NC_000962 3207939 3206428 -3 - 1512 MG(2+) CHELATASE FAMILY PROTEIN / ComM-related protein - none - gi|15610034 fig|83332.1.peg.2900 CDS NC_000962 3208325 3207939 -2 - 387 Predicted endonuclease distantly related to archaeal Holliday junction resolvase - none - gi|15610035 fig|83332.1.peg.2901 CDS NC_000962 3209403 3208573 -3 - 831 Formate dehydrogenase chain D (EC 1.2.1.2) Formate hydrogenase gi|15610036 fig|83332.1.peg.2902 CDS NC_000962 3211742 3209403 -2 - 2340 Putative formate dehydrogenase oxidoreductase protein Formate hydrogenase gi|15610037 fig|83332.1.peg.2903 CDS NC_000962 3212105 3211800 -2 - 306 Protein often found in Actinomycetes clustered with signal peptidase and/or RNaseHII Ribonuclease H gi|15610038 fig|83332.1.peg.2904 CDS NC_000962 3212953 3212159 -1 - 795 Ribonuclease HII (EC 3.1.26.4) Conserved gene cluster associated with Met-tRNA formyltransferase;
Ribonuclease H;
Ribonucleases in Bacillus gi|15610039 fig|83332.1.peg.2905 CDS NC_000962 3213851 3212967 -2 - 885 Signal peptidase I (EC 3.4.21.89) CBSS-176299.4.peg.1292;
Signal peptidase gi|15610040 fig|83332.1.peg.2906 CDS NC_000962 3214250 3213909 -2 - 342 LSU ribosomal protein L19p Ribosome LSU bacterial gi|15610041 fig|83332.1.peg.2907 CDS NC_000962 3214625 3215569 2 + 945 Putative lipoprotein lppW precursor - none - gi|15610042 fig|83332.1.peg.2908 CDS NC_000962 3216354 3215662 -3 - 693 tRNA (Guanine37-N1) -methyltransferase (EC 2.1.1.31) RNA methylation;
Ribosome biogenesis bacterial;
tRNA modification Bacteria gi|15610043 fig|83332.1.peg.2909 CDS NC_000962 3216888 3216358 -3 - 531 16S rRNA processing protein RimM KH domain RNA binding protein YlqC;
Ribosome biogenesis bacterial gi|15610044 fig|83332.1.peg.2910 CDS NC_000962 3217144 3216902 -1 - 243 KH domain RNA binding protein YlqC KH domain RNA binding protein YlqC gi|15610045 fig|83332.1.peg.2911 CDS NC_000962 3217640 3217152 -2 - 489 SSU ribosomal protein S16p KH domain RNA binding protein YlqC;
Ribosome SSU bacterial gi|15610046 fig|83332.1.peg.2912 CDS NC_000962 3218267 3217824 -2 - 444 hypothetical protein - none - gi|15610047 fig|83332.1.peg.2913 CDS NC_000962 3218336 3219211 2 + 876 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) CBSS-84588.1.peg.1247;
Metallocarboxypeptidases (EC 3.4.17.-);
Murein Hydrolases;
Peptidoglycan Biosynthesis gi|15610048 fig|83332.1.peg.2914 CDS NC_000962 3219858 3219271 -3 - 588 Transcriptional regulator, TetR family - none - gi|15610049 fig|83332.1.peg.2915 CDS NC_000962 3221695 3219860 -1 - 1836 N-acyl-D-glutamate amidohydrolase - none - gi|15610050 fig|83332.1.peg.2916 CDS NC_000962 3223521 3221764 -3 - 1758 Transmembrane serine/threonine-protein kinase I PknI (EC 2.7.11.1) - none - gi|15610051 fig|83332.1.peg.2917 CDS NC_000962 3224677 3223565 -1 - 1113 Metallo-dependent hydrolase - none - gi|15610052 fig|83332.1.peg.2918 CDS NC_000962 3226282 3224705 -1 - 1578 Signal recognition particle, subunit Ffh SRP54 (TC 3.A.5.1.1) Bacterial signal recognition particle (SRP);
Universal GTPases gi|15610053 fig|83332.1.peg.2919 CDS NC_000962 3226360 3228240 1 + 1881 DNA or RNA helicase of superfamily protein II - none - gi|15610054 fig|83332.1.peg.2920 CDS NC_000962 3230677 3228251 -1 - 2427 [Protein-PII] uridylyltransferase (EC 2.7.7.59) Ammonia assimilation;
CBSS-312309.3.peg.1965 gi|15610055 fig|83332.1.peg.2921 CDS NC_000962 3231073 3230735 -1 - 339 Nitrogen regulatory protein P-II - none - gi|15610056 fig|83332.1.peg.2922 CDS NC_000962 3232503 3231070 -3 - 1434 Ammonium transporter Ammonia assimilation gi|15610057 fig|83332.1.peg.2923 CDS NC_000962 3234136 3232868 -1 - 1269 Signal recognition particle receptor protein FtsY (=alpha subunit) (TC 3.A.5.1.1) Bacterial Cell Division;
Bacterial signal recognition particle (SRP);
Universal GTPases gi|15610058 fig|83332.1.peg.2924 CDS NC_000962 3238055 3234186 -2 - 3870 Chromosome partition protein smc DNA structural proteins, bacterial gi|15610059 fig|83332.1.peg.2925 CDS NC_000962 3238496 3238083 -2 - 414 hypothetical protein Rv2923c - none - gi|15610060 fig|83332.1.peg.2926 CDS NC_000962 3239467 3238598 -1 - 870 Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23) DNA Repair Base Excision gi|15610061 fig|83332.1.peg.2927 CDS NC_000962 3240548 3239826 -2 - 723 Ribonuclease III (EC 3.1.26.3) CBSS-176299.4.peg.1292;
RNA processing and degradation, bacterial gi|15610062 fig|83332.1.peg.2928 CDS NC_000962 3241168 3240545 -1 - 624 COG1399 protein, clustered with ribosomal protein L32p - none - gi|15610063 fig|83332.1.peg.2929 CDS NC_000962 3241956 3241219 -3 - 738 Cell division initiation protein - none - gi|15610064 fig|83332.1.peg.2930 CDS NC_000962 3242195 3242980 2 + 786 Thioesterase TesA - none - gi|15610065 fig|83332.1.peg.2931 CDS NC_000962 3242967 3243278 3 + 312 FIG051971: hypothetical protein - none - gi|15610066 fig|83332.1.peg.2932 CDS NC_000962 3243565 3245445 1 + 1881 Long-chain fatty-acid-AMP ligase, Mycobacterial subgroup FadD26 Biotin biosynthesis gi|15610067 fig|83332.1.peg.2933 CDS NC_000962 3245442 3251072 3 + 5631 Phenolpthiocerol synthesis type-I polyketide synthase PpsA - none - gi|15610068 fig|83332.1.peg.2934 CDS NC_000962 3251069 3255685 2 + 4617 Phenolpthiocerol synthesis type I polyketide synthase PpsB (EC 2.3.1.41) - none - gi|15610069 fig|83332.1.peg.2935 CDS NC_000962 3255682 3262248 1 + 6567 Phenolpthiocerol synthesis type-I polyketide synthase PpsC - none - gi|15610070 fig|83332.1.peg.2936 CDS NC_000962 3262245 3267728 3 + 5484 Phenolpthiocerol synthesis type-I polyketide synthase PpsD - none - gi|15610071 fig|83332.1.peg.2937 CDS NC_000962 3267734 3272200 2 + 4467 Phenolpthiocerol synthesis type-I polyketide synthase PpsE - none - gi|15610072 fig|83332.1.peg.2938 CDS NC_000962 3272211 3273206 3 + 996 Daunorubicin-DIM-transport ATP-binding protein ABC transporter DrrA - none - gi|15610073 fig|83332.1.peg.2939 CDS NC_000962 3273203 3274072 2 + 870 Daunorubicin-DIM-transport integral membrane protein ABC transporter DrrB - none - gi|15610074 fig|83332.1.peg.2940 CDS NC_000962 3274069 3274899 1 + 831 Daunorubicin-DIM-transport integral membrane protein ABC transporter DrrC - none - gi|15610075 fig|83332.1.peg.2941 CDS NC_000962 3274946 3276214 2 + 1269 Putative conserved polyketide synthase-associated protein PapA5 - none - gi|15610076 fig|83332.1.peg.2942 CDS NC_000962 3282712 3276377 -1 - 6336 Multifunctional mycocerosic acid synthase membrane-associated mas (Multi-functional membrane-associated mycocerosic acid synthase mas) - none - gi|15610077 fig|83332.1.peg.2943 CDS NC_000962 3283332 3285074 3 + 1743 Long-chain fatty-acid-AMP ligase, Mycobacterial subgroup FadD28 Biotin biosynthesis gi|15610078 fig|83332.1.peg.2944 CDS NC_000962 3285067 3287829 1 + 2763 Transmembrane transport protein MmpL7 - none - gi|15610079 fig|83332.1.peg.2945 CDS NC_000962 3288461 3289702 2 + 1242 PROBABLE TRANSPOSASE FOR INSERTION SEQUENCE ELEMENT IS1533 - none - gi|15610080 fig|83332.1.peg.2946 CDS NC_000962 3289787 3290503 2 + 717 ISMt3 transposase B2 - none - gi|15610081 fig|83332.1.peg.2947 CDS NC_000962 3291322 3290621 -1 - 702 Putative lipoprotein LppX precursor - none - gi|15610082 fig|83332.1.peg.2948 CDS NC_000962 3296350 3291500 -1 - 4851 Enoylreductase in polyketide synthases Pks1 - none - gi|15610083 fig|83332.1.peg.2949 CDS NC_000962 3297837 3296347 -3 - 1491 Polyketide synthase Pks15 - none - gi|15610084 fig|83332.1.peg.2950 CDS NC_000962 3299951 3297834 -2 - 2118 Long-chain fatty-acid-CoA ligase (EC 6.2.1.3), Mycobacterial subgroup FadD22 Mycobacterium virulence operon involved in lipid degradation gi|15610085 fig|83332.1.peg.2951 CDS NC_000962 3300567 3299968 -3 - 600 Chorismate--pyruvate lyase (EC 4.1.3.40) ## for phenolphthiocerol synthesis Mycobacterium virulence operon involved in lipid degradation;
Ubiquinone Biosynthesis gi|15610086 fig|83332.1.peg.2952 CDS NC_000962 3302452 3300593 -1 - 1860 Long-chain fatty-acid-AMP ligase, Mycobacterial subgroup FadD29 Biotin biosynthesis;
Mycobacterium virulence operon involved in lipid degradation gi|15610087 fig|83332.1.peg.2953 CDS NC_000962 3304245 3303100 -3 - 1146 Phthiodiolone/phenolphthiodiolone dimycocerosates ketoreductase - none - gi|15610088 fig|83332.1.peg.2954 CDS NC_000962 3304438 3305250 1 + 813 Phthiotriol/phenolphthiotriol dimycocerosates methyltransferase - none - gi|15610089 fig|83332.1.peg.2955 CDS NC_000962 3305276 3306532 2 + 1257 Trans-acting enoyl reductase - none - gi|15610090 fig|83332.1.peg.2956 CDS NC_000962 3307388 3306663 -2 - 726 FIG00821261: hypothetical protein - none - gi|15610091 fig|83332.1.peg.2957 CDS NC_000962 3308542 3307577 -1 - 966 methyltransferase, FkbM family domain protein - none - gi|15610092 fig|83332.1.peg.2958 CDS NC_000962 3308665 3309396 1 + 732 hypothetical protein Rv2956 - none - gi|15610093 fig|83332.1.peg.2959 CDS NC_000962 3309467 3310294 2 + 828 PGL/p-HBAD biosynthesis glycosyltransferase - none - gi|15610094 fig|83332.1.peg.2960 CDS NC_000962 3311997 3310711 -3 - 1287 UDP-glucoronosyl and UDP-glucosyltransferases family protein - none - gi|15610095 fig|83332.1.peg.2961 CDS NC_000962 3312835 3312098 -1 - 738 POSSIBLE METHYLTRANSFERASE (METHYLASE) - none - gi|15610096 fig|83332.1.peg.2962 CDS NC_000962 3313198 3312950 -1 - 249 FIG084684: hypothetical protein - none - gi|15610097 fig|83332.1.peg.2963 CDS NC_000962 3313280 3313669 2 + 390 PROBABLE TRANSPOSASE - none - gi|15610098 fig|83332.1.peg.2964 CDS NC_000962 3315119 3313770 -2 - 1350 UDP-glucoronosyl and UDP-glucosyltransferases family protein - none - gi|15610099 fig|83332.1.peg.2965 CDS NC_000962 3315233 3316453 2 + 1221 PROBABLE INTEGRAL MEMBRANE PROTEIN - none - gi|15610100 fig|83332.1.peg.2966 CDS NC_000962 3316526 3317458 2 + 933 Formyltetrahydrofolate deformylase (EC 3.5.1.10) 5-FCL-like protein;
One-carbon metabolism by tetrahydropterines gi|15610101 fig|83332.1.peg.2967 CDS NC_000962 3318812 3318327 -2 - 486 Phosphopantetheine adenylyltransferase (EC 2.7.7.3) CBSS-266117.6.peg.1260;
CBSS-269801.1.peg.1715;
Coenzyme A Biosynthesis gi|15610102 fig|83332.1.peg.2968 CDS NC_000962 3319464 3318898 -3 - 567 16S rRNA (guanine(966)-N(2))-methyltransferase (EC 2.1.1.171) ## SSU rRNA m(2)G966 CBSS-266117.6.peg.1260;
CBSS-269801.1.peg.1715;
RNA methylation gi|15610103 fig|83332.1.peg.2969 CDS NC_000962 3323043 3319660 -3 - 3384 Pyruvate carboxylase (EC 6.4.1.1) Pyruvate metabolism I: anaplerotic reactions, PEP gi|15610104 fig|83332.1.peg.2970 CDS NC_000962 3323700 3323068 -3 - 633 PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN - none - gi|15610105 fig|83332.1.peg.2971 CDS NC_000962 3324473 3323706 -2 - 768 POSSIBLE CONSERVED MEMBRANE OR SECRETED PROTEIN - none - gi|15610106 fig|83332.1.peg.2972 CDS NC_000962 3325700 3324570 -2 - 1131 lipase-esterase (lipN) - none - gi|15610107 fig|83332.1.peg.2973 CDS NC_000962 3326098 3326946 1 + 849 2,5-diketo-D-gluconic acid reductase (EC 1.1.1.-) - none - gi|15610108 fig|83332.1.peg.2974 CDS NC_000962 3327733 3327020 -1 - 714 Possible membrane protein - none - gi|15610109 fig|83332.1.peg.2975 CDS NC_000962 3329943 3327730 -3 - 2214 ATP-dependent DNA helicase RecG (EC 3.6.1.-) Transcription factors bacterial gi|15610110 fig|83332.1.peg.2976 CDS NC_000962 3331358 3329946 -2 - 1413 Dihydroxyacetone kinase family protein Glycerolipid and Glycerophospholipid Metabolism in Bacteria gi|15610111 fig|83332.1.peg.2977 CDS NC_000962 3331609 3331355 -1 - 255 Dihydroxyacetone kinase family protein Glycerolipid and Glycerophospholipid Metabolism in Bacteria gi|15610112 fig|83332.1.peg.2978 CDS NC_000962 3332751 3332068 -3 - 684 Uracil-DNA glycosylase, family 1 DNA Repair Base Excision;
Uracil-DNA glycosylase gi|15610113 fig|83332.1.peg.2979 CDS NC_000962 3333785 3332784 -2 - 1002 Thiamine-monophosphate kinase (EC 2.7.4.16) 5-FCL-like protein;
Riboflavin synthesis cluster;
Thiamin biosynthesis gi|15610114 fig|83332.1.peg.2980 CDS NC_000962 3335161 3333782 -1 - 1380 Mobile element protein - none - gi|15610115 fig|83332.1.peg.2981 CDS NC_000962 3335745 3335161 -3 - 585 Resolvase - none - gi|15610116 fig|83332.1.peg.2982 CDS NC_000962 3335957 3336502 2 + 546 Possible membrane protein - none - gi|15610117 fig|83332.1.peg.2983 CDS NC_000962 3337914 3336793 -3 - 1122 D-alanine--D-alanine ligase (EC 6.3.2.4) Peptidoglycan Biosynthesis;
Peptidoglycan biosynthesis--gjo gi|15610118 fig|83332.1.peg.2984 CDS NC_000962 3338996 3337992 -2 - 1005 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) Glutaredoxins;
Glycerol and Glycerol-3-phosphate Uptake and Utilization;
Glycerolipid and Glycerophospholipid Metabolism in Bacteria gi|15610119 fig|83332.1.peg.2985 CDS NC_000962 3339115 3339759 1 + 645 2-phospho-L-lactate guanylyltransferase (EC 2.7.7.68) - none - gi|15610120 fig|83332.1.peg.2986 CDS NC_000962 3339851 3342079 2 + 2229 Polyphosphate kinase (EC 2.7.4.1) High affinity phosphate transporter and control of PHO regulon;
Phosphate metabolism;
Polyphosphate;
Purine conversions gi|15610121 fig|83332.1.peg.2987 CDS NC_000962 3342162 3343115 3 + 954 Possible hydrolase mutT1 (EC 3.-.-.-) - none - gi|15610122 fig|83332.1.peg.2988 CDS NC_000962 3343817 3343173 -2 - 645 DNA-binding protein HU / low-complexity, AKP-rich domain DNA structural proteins, bacterial gi|15610123 fig|83332.1.peg.2989 CDS NC_000962 3344626 3344030 -1 - 597 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) Branched-Chain Amino Acid Biosynthesis;
Leucine Biosynthesis gi|15610124 fig|83332.1.peg.2990 CDS NC_000962 3346072 3344651 -1 - 1422 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) Branched-Chain Amino Acid Biosynthesis;
Leucine Biosynthesis gi|15610125 fig|83332.1.peg.2991 CDS NC_000962 3346144 3346845 1 + 702 Transcriptional regulator, IclR family - none - gi|15610126 fig|83332.1.peg.2992 CDS NC_000962 3347716 3346856 -1 - 861 Putative uncharacterized protein BCG_3011c - none - gi|15610127 fig|83332.1.peg.2993 CDS NC_000962 3347979 3348470 3 + 492 hypothetical protein Rv2991 - none - gi|15610128 fig|83332.1.peg.2994 CDS NC_000962 3350274 3348802 -3 - 1473 Glutamyl-tRNA synthetase (EC 6.1.1.17) @ Glutamyl-tRNA(Gln) synthetase (EC 6.1.1.24) ## unambiguous Heme and Siroheme Biosynthesis;
tRNA aminoacylation, Glu and Gln;
tRNA aminoacylation, Glu and Gln gi|15610129 fig|83332.1.peg.2995 CDS NC_000962 3350990 3350271 -2 - 720 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) / 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) Aromatic amino acid degradation;
Aromatic amino acid degradation gi|15610130 fig|83332.1.peg.2996 CDS NC_000962 3351266 3352603 2 + 1338 Integral membrane transport protein - none - gi|15610131 fig|83332.1.peg.2997 CDS NC_000962 3353465 3352455 -2 - 1011 3-isopropylmalate dehydrogenase (EC 1.1.1.85) Branched-Chain Amino Acid Biosynthesis;
Leucine Biosynthesis gi|15610132 fig|83332.1.peg.2998 CDS NC_000962 3355066 3353480 -1 - 1587 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) Glycine and Serine Utilization;
Pyridoxin (Vitamin B6) Biosynthesis;
Serine Biosynthesis gi|15610133 fig|83332.1.peg.2999 CDS NC_000962 3355096 3356538 1 + 1443 Phytoene dehydrogenase and related proteins Carotenoids gi|15610134 fig|83332.1.peg.3000 CDS NC_000962 3356812 3357273 1 + 462 FIG305449: hypothetical protein - none - gi|15610135 fig|83332.1.peg.3001 CDS NC_000962 3357599 3358564 2 + 966 Putative lipoprotein LppY - none - gi|15610136 fig|83332.1.peg.3002 CDS NC_000962 3358609 3359268 1 + 660 YbbM seven transmembrane helix protein Broadly distributed proteins not in subsystems gi|15610137 fig|83332.1.peg.3003 CDS NC_000962 3360583 3359582 -1 - 1002 Ketol-acid reductoisomerase (EC 1.1.1.86) Branched-Chain Amino Acid Biosynthesis;
Coenzyme A Biosynthesis gi|15610138 fig|83332.1.peg.3004 CDS NC_000962 3361127 3360621 -2 - 507 Acetolactate synthase small subunit (EC 2.2.1.6) Acetolactate synthase subunits;
Branched-Chain Amino Acid Biosynthesis gi|15610139 fig|83332.1.peg.3005 CDS NC_000962 3362983 3361127 -1 - 1857 Acetolactate synthase large subunit (EC 2.2.1.6) Acetolactate synthase subunits;
Branched-Chain Amino Acid Biosynthesis gi|15610140 fig|83332.1.peg.3006 CDS NC_000962 3363345 3363683 3 + 339 Low molecular weight protein antigen 6 - none - gi|15610141 fig|83332.1.peg.3007 CDS NC_000962 3364529 3363690 -2 - 840 Membrane protein 2, distant similarity to thiosulphate:quinone oxidoreductase DoxD - none - gi|15610142 fig|83332.1.peg.3008 CDS NC_000962 3364706 3365827 2 + 1122 Glucose/sorbosone dehydrogenase, lipoprotein LppZ - none - gi|15610143 fig|83332.1.peg.3009 CDS NC_000962 3366447 3365833 -3 - 615 Oxidoreductase - none - gi|15610144 fig|83332.1.peg.3010 CDS NC_000962 3366641 3367264 2 + 624 hypothetical protein Rv3008 - none - gi|15610145 fig|83332.1.peg.3011 CDS NC_000962 3368790 3367261 -3 - 1530 Aspartyl-tRNA(Asn) amidotransferase subunit B (EC 6.3.5.6) @ Glutamyl-tRNA(Gln) amidotransferase subunit B (EC 6.3.5.7) tRNA aminoacylation, Asp and Asn;
tRNA aminoacylation, Glu and Gln gi|15610146 fig|83332.1.peg.3012 CDS NC_000962 3369851 3368820 -2 - 1032 6-phosphofructokinase (EC 2.7.1.11) Glycolysis and Gluconeogenesis gi|15610147 fig|83332.1.peg.3013 CDS NC_000962 3371431 3369947 -1 - 1485 Aspartyl-tRNA(Asn) amidotransferase subunit A (EC 6.3.5.6) @ Glutamyl-tRNA(Gln) amidotransferase subunit A (EC 6.3.5.7) tRNA aminoacylation, Asp and Asn;
tRNA aminoacylation, Glu and Gln gi|15610148 fig|83332.1.peg.3014 CDS NC_000962 3371727 3371428 -3 - 300 Aspartyl-tRNA(Asn) amidotransferase subunit C (EC 6.3.5.6) @ Glutamyl-tRNA(Gln) amidotransferase subunit C (EC 6.3.5.7) tRNA aminoacylation, Asp and Asn;
tRNA aminoacylation, Glu and Gln gi|15610149 fig|83332.1.peg.3015 CDS NC_000962 3371812 3372468 1 + 657 hypothetical protein Rv3013 - none - gi|15610150 fig|83332.1.peg.3016 CDS NC_000962 3374617 3372542 -1 - 2076 DNA ligase (EC 6.5.1.2) DNA Repair Base Excision;
NAD and NADP cofactor biosynthesis global gi|15610151 fig|83332.1.peg.3017 CDS NC_000962 3375661 3374648 -1 - 1014 Vitamin-B12 independent methionine synthase family protein - none - gi|15610152 fig|83332.1.peg.3018 CDS NC_000962 3375755 3376384 2 + 630 Lipoprotein LpqA - none - gi|15610153 fig|83332.1.peg.3019 CDS NC_000962 3376849 3376487 -1 - 363 ESAT-6-like protein EsxQ - none - gi|15610154 fig|83332.1.peg.3020 CDS NC_000962 3378240 3376936 -3 - 1305 PPE family protein - none - gi|15610155 fig|83332.1.peg.3021 CDS NC_000962 3378998 3378708 -2 - 291 ESAT-6 like protein EsxR - none - gi|15610156 fig|83332.1.peg.3022 CDS NC_000962 3379326 3379033 -3 - 294 ESAT-6 like protein EsxS - none - gi|15610157 fig|83332.1.peg.3023 CDS NC_000962 3380449 3379373 -1 - 1077 PPE family protein - none - gi|15610158 fig|83332.1.peg.3024 CDS NC_000962 3380679 3380437 -3 - 243 PPE family protein - none - gi|15610159 fig|83332.1.peg.3025 CDS NC_000962 3382619 3381372 -2 - 1248 Mobile element protein - none - gi|15610160 fig|83332.1.peg.3026 CDS NC_000962 3383885 3382782 -2 - 1104 tRNA-specific 2-thiouridylase MnmA RNA methylation;
Riboflavin, FMN and FAD metabolism in plants;
mnm5U34 biosynthesis bacteria;
tRNA modification Bacteria gi|15610161 fig|83332.1.peg.3027 CDS NC_000962 3385063 3383882 -1 - 1182 Cysteine desulfurase (EC 2.8.1.7) Alanine biosynthesis;
CBSS-84588.1.peg.1247;
RNA methylation;
mnm5U34 biosynthesis bacteria;
tRNA modification Bacteria gi|15610162 fig|83332.1.peg.3028 CDS NC_000962 3386074 3385160 -1 - 915 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51) Glycerolipid and Glycerophospholipid Metabolism in Bacteria;
Phosphate metabolism;
Ribosome post-transcriptional modification and chromosomal segregation cluster gi|15610163 fig|83332.1.peg.3029 CDS NC_000962 3386811 3386071 -3 - 741 Putative hemolysin - none - gi|15610164 fig|83332.1.peg.3030 CDS NC_000962 3388028 3387072 -2 - 957 Electron transfer flavoprotein, alpha subunit Acetyl-CoA fermentation to Butyrate gi|15610165 fig|83332.1.peg.3031 CDS NC_000962 3388867 3388067 -1 - 801 Electron transfer flavoprotein, beta subunit Acetyl-CoA fermentation to Butyrate gi|15610166 fig|83332.1.peg.3032 CDS NC_000962 3389098 3389922 1 + 825 Methyltransferase (EC 2.1.1.-) - none - gi|15610167 fig|83332.1.peg.3033 CDS NC_000962 3389919 3391499 3 + 1581 Glycogen branching enzyme, GH-57-type, archaeal (EC 2.4.1.18) Glycogen metabolism gi|15610168 fig|83332.1.peg.3034 CDS NC_000962 3391531 3392775 1 + 1245 Glycosyl transferase, group 1 - none - gi|15610169 fig|83332.1.peg.3035 CDS NC_000962 3393377 3393925 2 + 549 hypothetical protein Rv3033 - none - gi|15610170 fig|83332.1.peg.3036 CDS NC_000962 3394918 3394016 -1 - 903 hypothetical protein Rv3034c - none - gi|15610171 fig|83332.1.peg.3037 CDS NC_000962 3395376 3396458 3 + 1083 hypothetical protein Rv3035 - none - gi|15610172 fig|83332.1.peg.3038 CDS NC_000962 3397138 3396455 -1 - 684 Possible membrane protein - none - gi|15610173 fig|83332.1.peg.3039 CDS NC_000962 3398287 3397211 -1 - 1077 Methyltransferase (EC 2.1.1.-) - none - gi|15610174 fig|83332.1.peg.3040 CDS NC_000962 3399405 3398422 -3 - 984 Methyltransferase domain - none - gi|15610175 fig|83332.1.peg.3041 CDS NC_000962 3400180 3399416 -1 - 765 Enoyl-CoA hydratase (EC 4.2.1.17) Acetyl-CoA fermentation to Butyrate;
Butanol Biosynthesis;
Fatty acid metabolism cluster;
Isoleucine degradation;
Polyhydroxybutyrate metabolism;
Valine degradation gi|15610176 fig|83332.1.peg.3042 CDS NC_000962 3401055 3400189 -3 - 867 Putative NUDIX/MutT-family hydrolase - none - gi|15610177 fig|83332.1.peg.3043 CDS NC_000962 3401915 3401052 -2 - 864 ABC transporter ATP-binding protein - none - gi|15610178 fig|83332.1.peg.3044 CDS NC_000962 3403159 3401930 -1 - 1230 Phosphoserine phosphatase (EC 3.1.3.3) CBSS-336982.3.peg.3874;
Glycine and Serine Utilization;
Serine Biosynthesis gi|15610179 fig|83332.1.peg.3045 CDS NC_000962 3404918 3403197 -2 - 1722 Cytochrome c oxidase polypeptide I (EC 1.9.3.1) Terminal cytochrome C oxidases gi|15610180 fig|83332.1.peg.3046 CDS NC_000962 3405133 3406212 1 + 1080 Iron(III) dicitrate transport system, periplasmic iron-binding protein FecB (TC 3.A.1.14.1) - none - gi|15610181 fig|83332.1.peg.3047 CDS NC_000962 3406282 3407322 1 + 1041 Cinnamyl alcohol dehydrogenase/reductase (EC 1.1.1.195) @ Alcohol dehydrogenase (EC 1.1.1.1) Glycerolipid and Glycerophospholipid Metabolism in Bacteria gi|15610182 fig|83332.1.peg.3048 CDS NC_000962 3407685 3407311 -3 - 375 hypothetical protein Rv3046c - none - gi|15610183 fig|83332.1.peg.3049 CDS NC_000962 3408303 3408019 -3 - 285 hypothetical protein Rv3047c - none - gi|15610184 fig|83332.1.peg.3050 CDS NC_000962 3409375 3408401 -1 - 975 Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1) Ribonucleotide reduction gi|15610185 fig|83332.1.peg.3051 CDS NC_000962 3411080 3409506 -2 - 1575 Monooxygenase, flavin-binding family - none - gi|15610186 fig|83332.1.peg.3052 CDS NC_000962 3411954 3411214 -3 - 741 Transcriptional regulator, TetR family - none - gi|15610187 fig|83332.1.peg.3053 CDS NC_000962 3414163 3412082 -1 - 2082 Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1) Ribonucleotide reduction gi|15610188 fig|83332.1.peg.3054 CDS NC_000962 3414681 3414229 -3 - 453 Ribonucleotide reduction protein NrdI Ribonucleotide reduction gi|15610189 fig|83332.1.peg.3055 CDS NC_000962 3414955 3414716 -1 - 240 Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib Glutaredoxins;
Ribonucleotide reduction gi|15610190 fig|83332.1.peg.3056 CDS NC_000962 3415986 3415432 -3 - 555 NADPH:quinone oxidoreductase - none - gi|15610191 fig|83332.1.peg.3057 CDS NC_000962 3416078 3416692 2 + 615 Transcriptional regulator, TetR family - none - gi|15610192 fig|83332.1.peg.3058 CDS NC_000962 3416702 3417742 2 + 1041 DNA polymerase-like protein MT3142 DNA repair, bacterial gi|15610193 fig|83332.1.peg.3059 CDS NC_000962 3418659 3417796 -3 - 864 Short chain dehydrogenase - none - gi|15610194 fig|83332.1.peg.3060 CDS NC_000962 3419373 3418723 -3 - 651 Transcriptional regulator, TetR family - none - gi|15610195 fig|83332.1.peg.3061 CDS NC_000962 3419489 3420967 2 + 1479 Cytochrome P450 136 - none - gi|15610196 fig|83332.1.peg.3062 CDS NC_000962 3423210 3421738 -3 - 1473 Transcriptional regulator, GntR family - none - gi|15610197 fig|83332.1.peg.3063 CDS NC_000962 3425424 3423259 -3 - 2166 Acyl-CoA dehydrogenase FadE22 - none - gi|15610198 fig|83332.1.peg.3064 CDS NC_000962 3425581 3427104 1 + 1524 ATP-dependent DNA ligase (EC 6.5.1.1) DNA Repair Base Excision;
DNA ligases gi|15610199 fig|83332.1.peg.3065 CDS NC_000962 3427240 3429516 1 + 2277 Carbon starvation protein A Carbon Starvation;
Stress related cluster gi|15610200 fig|83332.1.peg.3066 CDS NC_000962 3430247 3429822 -2 - 426 Possible membrane protein - none - gi|15610201 fig|83332.1.peg.3067 CDS NC_000962 3430384 3430707 1 + 324 Multidrug resistance protein mmr - none - gi|15610202 fig|83332.1.peg.3068 CDS NC_000962 3430704 3431312 3 + 609 Transcriptional regulator, TetR family - none - gi|15610203 fig|83332.1.peg.3069 CDS NC_000962 3431425 3431835 1 + 411 hypothetical protein Rv3067 - none - gi|15610204 fig|83332.1.peg.3070 CDS NC_000962 3433619 3431976 -2 - 1644 Phosphoglucomutase (EC 5.4.2.2) Glycogen metabolism gi|15610205 fig|83332.1.peg.3071 CDS NC_000962 3433689 3434087 3 + 399 Protein CrcB homolog 1 - none - gi|15610206 fig|83332.1.peg.3072 CDS NC_000962 3434084 3434464 2 + 381 Protein CrcB homolog 2 - none - gi|15610207 fig|83332.1.peg.3073 CDS NC_000962 3434461 3435570 1 + 1110 hypothetical protein Rv3071 - none - gi|15610208 fig|83332.1.peg.3074 CDS NC_000962 3436319 3435795 -2 - 525 Probable F420-dependent oxidoreductase family protein - none - gi|15610209 fig|83332.1.peg.3075 CDS NC_000962 3436682 3436326 -2 - 357 FIG016027: protein of unknown function YeaO - none - gi|15610210 fig|83332.1.peg.3076 CDS NC_000962 3436776 3438050 3 + 1275 FIG029007: hypothetical protein - none - gi|15610211 fig|83332.1.peg.3077 CDS NC_000962 3438970 3438047 -1 - 924 Citrate lyase beta chain (EC 4.1.3.6) TCA Cycle gi|15610212 fig|83332.1.peg.3078 CDS NC_000962 3439069 3439545 1 + 477 hypothetical protein Rv3076 - none - gi|15610213 fig|83332.1.peg.3079 CDS NC_000962 3439538 3441349 2 + 1812 Choline-sulfatase (EC 3.1.6.6) - none - gi|15610214 fig|83332.1.peg.3080 CDS NC_000962 3441350 3441751 2 + 402 Hydroxylaminobenzene mutase hab - none - gi|15610215 fig|83332.1.peg.3081 CDS NC_000962 3442594 3441767 -1 - 828 Probable F420-dependent oxidoreductase family protein - none - gi|15610216 fig|83332.1.peg.3082 CDS NC_000962 3445985 3442653 -2 - 3333 (MTV013.01c-MTCY22D7.01), len: 1110. pknK.Probable serine-threonine protein kinase, similar to several in N-terminal half. C-terminal part from aa 300 related to N-terminal parts of Klebsiella pneumoniae CG43 aco operon regulatory protein ACOK (921 aa) and Escherichia coli MalT. Contains PS00107 Protein kinases ATP-binding region signature and PS00017 ATP/GTP-binding site motif A (P-loop). FASTA scores: sptr|P71584|P71584 HYPOTHETICAL 66.5 KD PROTEIN (626 aa) opt: 494 z-score: 399.1 E(): 9.6e-15; (32.6% identity in 371 aa overlap); and Acoptr|Q48411|Q48411 ACOK (921 aa) opt: 594 z-score: 475.1 E(): 5.6e-19; 30.8% identity in 354 aa overlap. TBparse score is 0.890 - none - gi|15610217 fig|83332.1.peg.3083 CDS NC_000962 3446037 3447275 3 + 1239 hypothetical protein Rv3081 - none - gi|15610218 fig|83332.1.peg.3084 CDS NC_000962 3448423 3447401 -1 - 1023 Transcriptional regulator, AraC family - none - gi|15610219 fig|83332.1.peg.3085 CDS NC_000962 3448501 3449988 1 + 1488 hypothetical protein Rv3083 - none - gi|15610220 fig|83332.1.peg.3086 CDS NC_000962 3449994 3450920 3 + 927 Esterase/lipase - none - gi|15610221 fig|83332.1.peg.3087 CDS NC_000962 3450917 3451747 2 + 831 Oxidoreductase, short-chain dehydrogenase/reductase family - none - gi|15610222 fig|83332.1.peg.3088 CDS NC_000962 3451778 3452884 2 + 1107 (MTV013.07), len: 368. adhD. Probable alcohol dehydrogenase similar to many especially MTCY369.06c. Contains PS00059 Zinc-containing alcohol dehydrogenases signature. FASTA scores: gp|Z80226|MTCY369_6 Mycobacterium tuberculosis cosmid (375 aa) opt: 1186 z-score: 1364.9 E(): 0;(47.3% identity in 368 aa overlap). TBparse score is 0.871 - none - gi|15610223 fig|83332.1.peg.3089 CDS NC_000962 3452922 3454340 3 + 1419 Diacyglycerol O-acyltransferase (EC 2.3.1.20) - none - gi|15610224 fig|83332.1.peg.3090 CDS NC_000962 3454337 3455761 2 + 1425 hypothetical protein Rv3088 - none - gi|15610225 fig|83332.1.peg.3091 CDS NC_000962 3455758 3457269 1 + 1512 Long-chain fatty-acid-CoA ligase (EC 6.2.1.3), Mycobacterial subgroup FadD13 Biotin biosynthesis;
Fatty acid metabolism cluster gi|15610226 fig|83332.1.peg.3092 CDS NC_000962 3458208 3459095 3 + 888 FIG00821598: hypothetical membrane protein - none - gi|15610227 fig|83332.1.peg.3093 CDS NC_000962 3459113 3460804 2 + 1692 hypothetical protein Rv3091 - none - gi|15610228 fig|83332.1.peg.3094 CDS NC_000962 3461731 3460811 -1 - 921 Possible membrane protein - none - gi|15610229 fig|83332.1.peg.3095 CDS NC_000962 3462761 3461757 -2 - 1005 Probable F420-dependent oxidoreductase family protein - none - gi|15610230 fig|83332.1.peg.3096 CDS NC_000962 3463888 3462758 -1 - 1131 hypothetical protein Rv3094c - none - gi|15610231 fig|83332.1.peg.3097 CDS NC_000962 3463970 3464446 2 + 477 Transcriptional regulator, HxlR family - none - gi|15610232 fig|83332.1.peg.3098 CDS NC_000962 3464544 3465683 3 + 1140 Cellulase (glycosyl hydrolase family 5) - none - gi|15610233 fig|83332.1.peg.3099 CDS NC_000962 3467088 3465775 -3 - 1314 (MTCY164.08c), len: 436. Esterase/lipase, identical to TR:P77909 (EMBL:U76006) ESTERASE/LIPASE (EC 3.1.1.3) (TRIACYLGLYCEROL LIPASE) (437 aa); N-terminal similar to N-terminal of M. tuberculosis PE family members, eg Y03A_MYCTU Q10637 hypothetical glycine-rich 49.6 kd pro (603 aa), fasta scores, opt: 334 E(): 4.8e-13, (43.4% identity in 152 aa overlap). Other relatives include MTCY1A11.25c, 7.8e-14; MTCY21B4.13c, 2.4e-12; MTCY270.06, 5.4e-12; MTCY359.33, 1.2e-11; MTC1A11.04, 1.2ee-11; cY130.seq, 1.3e-11 - none - gi|15610234 fig|83332.1.peg.3100 CDS NC_000962 3467659 3467207 -1 - 453 hypothetical protein Rv3098c - none - gi|15610235 fig|83332.1.peg.3101 CDS NC_000962 3469261 3468410 -1 - 852 hypothetical protein Rv3099c - none - gi|15610236 fig|83332.1.peg.3102 CDS NC_000962 3469780 3469298 -1 - 483 tmRNA-binding protein SmpB Heat shock dnaK gene cluster extended;
Translation termination factors bacterial gi|15610237 fig|83332.1.peg.3103 CDS NC_000962 3470676 3469783 -3 - 894 Cell division protein FtsX Bacterial Cell Division gi|15610238 fig|83332.1.peg.3104 CDS NC_000962 3471366 3470677 -3 - 690 Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1) Bacterial Cell Division gi|15610239 fig|83332.1.peg.3105 CDS NC_000962 3471847 3471410 -1 - 438 Hypothetical proline-rich protein - none - gi|15610240 fig|83332.1.peg.3106 CDS NC_000962 3472775 3471849 -2 - 927 Potassium efflux system KefA protein / Small-conductance mechanosensitive channel Glutathione-regulated potassium-efflux system and associated functions;
Potassium homeostasis gi|15610241 fig|83332.1.peg.3107 CDS NC_000962 3473901 3472765 -3 - 1137 Peptide chain release factor 2 Programmed frameshift;
Translation termination factors bacterial gi|15610242 fig|83332.1.peg.3108 CDS NC_000962 3474004 3475374 1 + 1371 Ferredoxin--NADP(+) reductase, actinobacterial (eukaryote-like) type (EC 1.18.1.2) Inorganic Sulfur Assimilation gi|15610243 fig|83332.1.peg.3109 CDS NC_000962 3476958 3475375 -3 - 1584 Possible alkyldihydroxyacetonephosphate synthase AgpS (EC 2.5.1.26) - none - gi|15610244 fig|83332.1.peg.3110 CDS NC_000962 3477057 3477497 3 + 441 hypothetical protein Rv3108 - none - gi|15610245 fig|83332.1.peg.3111 CDS NC_000962 3477646 3478725 1 + 1080 Molybdenum cofactor biosynthesis protein MoaA Molybdenum cofactor biosynthesis;
ar-104-EC Molybdenum cofactor biosynthesis moaABCDE gi|15610246 fig|83332.1.peg.3112 CDS NC_000962 3478776 3479171 3 + 396 Pterin-4-alpha-carbinolamine dehydratase (EC 4.2.1.96) Pterin biosynthesis;
Pterin carbinolamine dehydratase gi|15610247 fig|83332.1.peg.3113 CDS NC_000962 3479168 3479680 2 + 513 Molybdenum cofactor biosynthesis protein MoaC Molybdenum cofactor biosynthesis;
ar-104-EC Molybdenum cofactor biosynthesis moaABCDE gi|15610248 fig|83332.1.peg.3114 CDS NC_000962 3479697 3479948 3 + 252 Molybdenum cofactor biosynthesis protein MoaD Molybdenum cofactor biosynthesis;
ar-104-EC Molybdenum cofactor biosynthesis moaABCDE gi|15610249 fig|83332.1.peg.3115 CDS NC_000962 3480071 3480739 2 + 669 Hydrolase, haloacid dehalogenase-like family - none - gi|15610250 fig|83332.1.peg.3116 CDS NC_000962 3480756 3481286 3 + 531 Cytidine and deoxycytidylate deaminase family protein - none - gi|15610251 fig|83332.1.peg.3117 CDS NC_000962 3481448 3482695 2 + 1248 Mobile element protein - none - gi|15610252 fig|83332.1.peg.3118 CDS NC_000962 3482773 3483942 1 + 1170 Sulfur carrier protein adenylyltransferase ThiF Molybdenum cofactor biosynthesis;
Thiamin biosynthesis gi|15610253 fig|83332.1.peg.3119 CDS NC_000962 3483971 3484804 2 + 834 Thiosulfate sulfurtransferase, rhodanese (EC 2.8.1.1) Single-Rhodanese-domain proteins gi|15610254 fig|83332.1.peg.3120 CDS NC_000962 3484806 3485108 3 + 303 Putative sulfur metabolism protein SseC2 - none - gi|15610255 fig|83332.1.peg.3121 CDS NC_000962 3485129 3485572 2 + 444 Molybdenum cofactor biosynthesis protein MoaE Molybdenum cofactor biosynthesis;
ar-104-EC Molybdenum cofactor biosynthesis moaABCDE gi|15610256 fig|83332.1.peg.3122 CDS NC_000962 3485569 3486171 1 + 603 Possible methyltransferase (EC 2.1.1.-) - none - gi|15610257 fig|83332.1.peg.3123 CDS NC_000962 3486506 3487708 2 + 1203 Cytochrome P450 141 - none - gi|15610258 fig|83332.1.peg.3124 CDS NC_000962 3488086 3488556 1 + 471 hypothetical protein Rv3122 - none - gi|15610259 fig|83332.1.peg.3125 CDS NC_000962 3488566 3489060 1 + 495 hypothetical protein Rv3123 - none - gi|15610260 fig|83332.1.peg.3126 CDS NC_000962 3489503 3490372 2 + 870 transcriptional regulator, AfsR/DnrI/RedD family - none - gi|15610261 fig|83332.1.peg.3127 CDS NC_000962 3491648 3490473 -2 - 1176 PPE family protein - none - gi|15610262 fig|83332.1.peg.3128 CDS NC_000962 3492119 3491805 -2 - 315 hypothetical protein Rv3126c - none - gi|15610263 fig|83332.1.peg.3129 CDS NC_000962 3492144 3493178 3 + 1035 Nitroreductase - none - gi|15610264 fig|83332.1.peg.3130 CDS NC_000962 3494178 3493165 -3 - 1014 hypothetical protein - none - gi|15611066 fig|83332.1.peg.3131 CDS NC_000962 3494657 3494989 2 + 333 Probable DNA-binding protein - none - gi|15610265 fig|83332.1.peg.3132 CDS NC_000962 3496363 3494972 -1 - 1392 Diacyglycerol O-acyltransferase (EC 2.3.1.20) - none - gi|15610266 fig|83332.1.peg.3133 CDS NC_000962 3496548 3497546 3 + 999 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 - none - gi|15610267 fig|83332.1.peg.3134 CDS NC_000962 3499262 3497526 -2 - 1737 Two component system sensor histidine kinase DevS - none - gi|15610268 fig|83332.1.peg.3135 CDS NC_000962 3499912 3499259 -1 - 654 Two component transcriptional regulatory protein DevR - none - gi|15610269 fig|83332.1.peg.3136 CDS NC_000962 3500746 3499940 -1 - 807 Universal stress protein family Universal stress protein family gi|15610270 fig|83332.1.peg.3137 CDS NC_000962 3501331 3501729 1 + 399 PPE family protein - none - gi|15610271 fig|83332.1.peg.3138 CDS NC_000962 3501791 3502933 2 + 1143 (MTCY03A2.22c), len: 380, unknown, PPE-FAMILY PROTEIN,Gly-Ala-rich family, similar to MTV002_36, MTCI125_26, MTCY10G2_10, MTCI364_8, MTV049_28, MTV049_29, etc. FASTA scores: O33312 PPE-FAMILY PROTEIN, opt: 917 z-score: 858.7 E(): 0; 46.1% identity in 388 aa overlap. TBparse score is 0.923 - none - gi|15610272 fig|83332.1.peg.3139 CDS NC_000962 3503390 3504172 2 + 783 Histidinol-phosphatase [alternative form] (EC 3.1.3.15) Histidine Biosynthesis gi|15610273 fig|83332.1.peg.3140 CDS NC_000962 3504192 3505280 3 + 1089 Pyruvate formate lyase activating protein PflA - none - gi|15610274 fig|83332.1.peg.3141 CDS NC_000962 3505360 3506766 1 + 1407 Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.8.1) - none - gi|15610275 fig|83332.1.peg.3142 CDS NC_000962 3506787 3507992 3 + 1206 Probable acyl-CoA dehydrogenase (EC 1.3.99.3) Isoleucine degradation;
Valine degradation gi|15610276 fig|83332.1.peg.3143 CDS NC_000962 3508092 3509063 3 + 972 Probable NADPH quinone oxidoreductase FadB4 - none - gi|15610277 fig|83332.1.peg.3144 CDS NC_000962 3509543 3509115 -2 - 429 FIG00820149: hypothetical protein - none - gi|15610278 fig|83332.1.peg.3145 CDS NC_000962 3509651 3510052 2 + 402 Probable response regulator - none - gi|15610279 fig|83332.1.peg.3146 CDS NC_000962 3511314 3510085 -3 - 1230 PPE family protein CBSS-164757.7.peg.5020 gi|15610280 fig|83332.1.peg.3147 CDS NC_000962 3511679 3512065 2 + 387 NADH ubiquinone oxidoreductase chain A (EC 1.6.5.3) NADH ubiquinone oxidoreductase;
Respiratory Complex I gi|15610281 fig|83332.1.peg.3148 CDS NC_000962 3512074 3512628 1 + 555 NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3) NADH ubiquinone oxidoreductase;
Respiratory Complex I gi|15610282 fig|83332.1.peg.3149 CDS NC_000962 3512625 3513335 3 + 711 NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3) NADH ubiquinone oxidoreductase;
Respiratory Complex I gi|15610283 fig|83332.1.peg.3150 CDS NC_000962 3513335 3514657 2 + 1323 NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3) NADH ubiquinone oxidoreductase;
Respiratory Complex I gi|15610284 fig|83332.1.peg.3151 CDS NC_000962 3514654 3515412 1 + 759 NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3) NADH ubiquinone oxidoreductase;
Respiratory Complex I gi|15610285 fig|83332.1.peg.3152 CDS NC_000962 3515409 3516746 3 + 1338 NADH-ubiquinone oxidoreductase chain F (EC 1.6.5.3) NADH ubiquinone oxidoreductase;
Respiratory Complex I gi|15610286 fig|83332.1.peg.3153 CDS NC_000962 3516743 3519163 2 + 2421 NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3) NADH ubiquinone oxidoreductase;
Respiratory Complex I gi|15610287 fig|83332.1.peg.3154 CDS NC_000962 3519279 3520511 3 + 1233 NADH-ubiquinone oxidoreductase chain H (EC 1.6.5.3) NADH ubiquinone oxidoreductase;
Respiratory Complex I gi|15610288 fig|83332.1.peg.3155 CDS NC_000962 3520504 3521139 1 + 636 NADH-ubiquinone oxidoreductase chain I (EC 1.6.5.3) NADH ubiquinone oxidoreductase;
Respiratory Complex I gi|15610289 fig|83332.1.peg.3156 CDS NC_000962 3521136 3521924 3 + 789 NADH-ubiquinone oxidoreductase chain J (EC 1.6.5.3) NADH ubiquinone oxidoreductase;
Respiratory Complex I gi|15610290 fig|83332.1.peg.3157 CDS NC_000962 3521921 3522220 2 + 300 NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3) NADH ubiquinone oxidoreductase;
Respiratory Complex I gi|15610291 fig|83332.1.peg.3158 CDS NC_000962 3522231 3524132 3 + 1902 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) NADH ubiquinone oxidoreductase;
Respiratory Complex I gi|15610292 fig|83332.1.peg.3159 CDS NC_000962 3524129 3525790 2 + 1662 NADH-ubiquinone oxidoreductase chain M (EC 1.6.5.3) NADH ubiquinone oxidoreductase;
Respiratory Complex I gi|15610293 fig|83332.1.peg.3160 CDS NC_000962 3525787 3527382 1 + 1596 NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3) NADH ubiquinone oxidoreductase;
Respiratory Complex I gi|15610294 fig|83332.1.peg.3161 CDS NC_000962 3529160 3527388 -2 - 1773 PPE family protein - none - gi|15610295 fig|83332.1.peg.3162 CDS NC_000962 3529976 3529335 -2 - 642 Transcriptional regulator, TetR family - none - gi|15610296 fig|83332.1.peg.3163 CDS NC_000962 3531135 3529987 -3 - 1149 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - none - gi|15610297 fig|83332.1.peg.3164 CDS NC_000962 3531642 3531205 -3 - 438 Possible membrane protein - none - gi|15610298 fig|83332.1.peg.3165 CDS NC_000962 3532910 3531639 -2 - 1272 Possible membrane protein - none - gi|15610299 fig|83332.1.peg.3166 CDS NC_000962 3533902 3532940 -1 - 963 Probable methanol dehydrogenase transcriptional regulatory protein MoxR3 - none - gi|15610300 fig|83332.1.peg.3167 CDS NC_000962 3534392 3533910 -2 - 483 Putative uncharacterized protein BCG_3189c - none - gi|15610301 fig|83332.1.peg.3168 CDS NC_000962 3535348 3534389 -1 - 960 Putative uncharacterized protein BCG_3190c - none - gi|15610302 fig|83332.1.peg.3169 CDS NC_000962 3536054 3535428 -2 - 627 Transcriptional regulator, TetR family - none - gi|15610303 fig|83332.1.peg.3170 CDS NC_000962 3536099 3537235 2 + 1137 Phosphotransferase - none - gi|15610304 fig|83332.1.peg.3171 CDS NC_000962 3537235 3538359 1 + 1125 Putative uncharacterized protein BCG_3193 - none - gi|15610305 fig|83332.1.peg.3172 CDS NC_000962 3538502 3539848 2 + 1347 Amine oxidase [flavin-containing] A (EC 1.4.3.4) Threonine degradation gi|15610306 fig|83332.1.peg.3173 CDS NC_000962 3540742 3539843 -1 - 900 Non-heme haloperoxidase Hpx - none - gi|15610307 fig|83332.1.peg.3174 CDS NC_000962 3541361 3540879 -2 - 483 hypothetical protein Rv3172c - none - gi|15610308 fig|83332.1.peg.3175 CDS NC_000962 3542042 3541440 -2 - 603 Transcriptional regulator, TetR family - none - gi|15610309 fig|83332.1.peg.3176 CDS NC_000962 3542135 3542842 2 + 708 Oxidoreductase, short-chain dehydrogenase/reductase family - none - gi|15610310 fig|83332.1.peg.3177 CDS NC_000962 3542857 3544344 1 + 1488 Amidase - none - gi|15610311 fig|83332.1.peg.3178 CDS NC_000962 3545297 3544341 -2 - 957 Epoxide hydrolase (EC 3.3.2.9) CBSS-410289.13.peg.3174 gi|15610312 fig|83332.1.peg.3179 CDS NC_000962 3545444 3546304 2 + 861 Beta-ketoadipate enol-lactone hydrolase (EC 3.1.1.24) - none - gi|15610313 fig|83332.1.peg.3180 CDS NC_000962 3546435 3546794 3 + 360 Deazaflavin-dependent nitroreductase family protein - none - gi|15610314 fig|83332.1.peg.3181 CDS NC_000962 3547615 3548904 1 + 1290 ATPase - none - gi|15610315 fig|83332.1.peg.3182 CDS NC_000962 3549685 3549251 -1 - 435 FIG035400: Hypothetical protein CBSS-410289.13.peg.3174 gi|15610316 fig|83332.1.peg.3183 CDS NC_000962 3550140 3549688 -3 - 453 FIG031049: Hypothetical protein CBSS-410289.13.peg.3174 gi|15610317 fig|83332.1.peg.3184 CDS NC_000962 3550371 3550715 3 + 345 FIG032362: Hypothetical protein CBSS-410289.13.peg.3174 gi|15610318 fig|83332.1.peg.3185 CDS NC_000962 3550712 3551041 2 + 330 FIG036183: Transcriptional regulator, XRE family CBSS-410289.13.peg.3174 gi|15610319 fig|83332.1.peg.3186 CDS NC_000962 3551278 3551604 1 + 327 Mobile element protein - none - gi|15610320 fig|83332.1.peg.3187 CDS NC_000962 3551601 3552539 3 + 939 Mobile element protein - none - gi|15610321 fig|83332.1.peg.3188 CDS NC_000962 3552761 3553087 2 + 327 Mobile element protein - none - gi|15610322 fig|83332.1.peg.3189 CDS NC_000962 3553084 3554022 1 + 939 Mobile element protein - none - gi|15610323 fig|83332.1.peg.3190 CDS NC_000962 3554295 3554642 3 + 348 FIG046480: Hypothetical protein CBSS-410289.13.peg.3174 gi|15610324 fig|83332.1.peg.3191 CDS NC_000962 3554639 3555259 2 + 621 FIG043360: Hypothetical protein CBSS-410289.13.peg.3174 gi|15610325 fig|83332.1.peg.3192 CDS NC_000962 3556684 3555419 -1 - 1266 FIG030803: Hypothetical protein CBSS-410289.13.peg.3174 gi|15610326 fig|83332.1.peg.3193 CDS NC_000962 3558342 3557308 -3 - 1035 Mobile element protein - none - gi|15610327 fig|83332.1.peg.3194 CDS NC_000962 3559560 3560021 3 + 462 Putative F420-dependent oxidoreductase family protein - none - gi|15610328 fig|83332.1.peg.3195 CDS NC_000962 3563169 3560191 -3 - 2979 Possible membrane protein - none - gi|15610329 fig|83332.1.peg.3196 CDS NC_000962 3564283 3563261 -1 - 1023 Lon-like protease with PDZ domain CBSS-269801.1.peg.1715 gi|15610330 fig|83332.1.peg.3197 CDS NC_000962 3564361 3565779 1 + 1419 FIG020400: hypothetical protein - none - gi|15610331 fig|83332.1.peg.3198 CDS NC_000962 3565785 3566684 3 + 900 FIG00822196: hypothetical protein - none - gi|15610332 fig|83332.1.peg.3199 CDS NC_000962 3567021 3568364 3 + 1344 ABC1 family protein Namu_1592 - none - gi|15610333 fig|83332.1.peg.3200 CDS NC_000962 3571208 3569106 -2 - 2103 ATP-dependent DNA helicase UvrD/PcrA, actinomycete paralog DNA repair, bacterial UvrD and related helicases;
WhiB and WhiB-type regulatory proteins gi|15610334 fig|83332.1.peg.3201 CDS NC_000962 3572540 3571599 -2 - 942 NADH pyrophosphatase (EC 3.6.1.22) Nudix proteins (nucleoside triphosphate hydrolases) gi|15610335 fig|83332.1.peg.3202 CDS NC_000962 3573666 3572599 -3 - 1068 Potassium channel protein - none - gi|15610336 fig|83332.1.peg.3203 CDS NC_000962 3577033 3573728 -1 - 3306 ATP-dependent DNA helicase SCO5184 DNA repair, bacterial RecBCD pathway gi|15610337 fig|83332.1.peg.3204 CDS NC_000962 3580197 3577030 -3 - 3168 ATP-dependent DNA helicase SCO5183 DNA repair, bacterial RecBCD pathway gi|15610338 fig|83332.1.peg.3205 CDS NC_000962 3580635 3581309 3 + 675 Lipase LipV - none - gi|15610339 fig|83332.1.peg.3206 CDS NC_000962 3581312 3581617 2 + 306 Methylated DNA-protein cysteine methyltransferase - none - gi|15610340 fig|83332.1.peg.3207 CDS NC_000962 3582502 3581624 -1 - 879 hypothetical protein Rv3205c - none - gi|15610341 fig|83332.1.peg.3208 CDS NC_000962 3583707 3582529 -3 - 1179 Sulfur carrier protein adenylyltransferase ThiF Molybdenum cofactor biosynthesis;
Thiamin biosynthesis gi|15610342 fig|83332.1.peg.3209 CDS NC_000962 3584655 3583798 -3 - 858 FIG00820929: hypothetical protein - none - gi|15610343 fig|83332.1.peg.3210 CDS NC_000962 3585001 3585687 1 + 687 Transcriptional regulator, TetR family - none - gi|15610344 fig|83332.1.peg.3211 CDS NC_000962 3586271 3586831 2 + 561 probable membrane protein - none - gi|15610345 fig|83332.1.peg.3212 CDS NC_000962 3587536 3586841 -1 - 696 hypothetical protein - none - gi|15610346 fig|83332.1.peg.3213 CDS NC_000962 3587795 3589378 2 + 1584 ATP-dependent RNA helicase - none - gi|15610347 fig|83332.1.peg.3214 CDS NC_000962 3589391 3590614 2 + 1224 Possible membrane protein - none - gi|15610348 fig|83332.1.peg.3215 CDS NC_000962 3591489 3590689 -3 - 801 Chromosome (plasmid) partitioning protein ParA / Sporulation initiation inhibitor protein Soj Bacterial Cell Division;
Bacterial Cytoskeleton;
Bacterial Cytoskeleton;
RNA modification and chromosome partitioning cluster;
Ribosome post-transcriptional modification and chromosomal segregation cluster gi|15610349 fig|83332.1.peg.3216 CDS NC_000962 3591643 3592254 1 + 612 putative phosphoglycerate mutase family protein - none - gi|15610350 fig|83332.1.peg.3217 CDS NC_000962 3592251 3593369 3 + 1119 Isochorismate synthase (EC 5.4.4.2) Chorismate: Intermediate for synthesis of Tryptophan, PAPA antibiotics, PABA, 3-hydroxyanthranilate and more.;
Menaquinone and Phylloquinone Biosynthesis -- gjo gi|15610351 fig|83332.1.peg.3218 CDS NC_000962 3593517 3593849 3 + 333 GCN5-related N-acetyltransferase - none - gi|15610352 fig|83332.1.peg.3219 CDS NC_000962 3594232 3593801 -1 - 432 PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN - none - gi|15610353 fig|83332.1.peg.3220 CDS NC_000962 3594465 3595430 3 + 966 Transcription regulator [contains diacylglycerol kinase catalytic domain] - none - gi|15610354 fig|83332.1.peg.3221 CDS NC_000962 3595710 3595964 3 + 255 WhiB-like transcription regulator WhiB and WhiB-type regulatory proteins gi|15610355 fig|83332.1.peg.3222 CDS NC_000962 3597531 3596026 -3 - 1506 Signal transduction histidine kinase, subgroup 2 WhiB and WhiB-type regulatory proteins gi|15610356 fig|83332.1.peg.3223 CDS NC_000962 3597763 3597548 -1 - 216 Biotin carboxyl carrier protein Pyruvate metabolism I: anaplerotic reactions, PEP gi|15610357 fig|83332.1.peg.3224 CDS NC_000962 3598900 3598349 -1 - 552 hypothetical protein - none - gi|15610358 fig|83332.1.peg.3225 CDS NC_000962 3599547 3598897 -3 - 651 RNA polymerase sigma factor RpoE - none - gi|15610359 fig|83332.1.peg.3226 CDS NC_000962 3599847 3600695 3 + 849 Oxidoreductase, short-chain dehydrogenase/reductase family - none - gi|15610360 fig|83332.1.peg.3227 CDS NC_000962 3600631 3601015 1 + 384 Cys-tRNA(Pro) deacylase YbaK # fragment tRNA aminoacylation, Pro gi|15611067 fig|83332.1.peg.3228 CDS NC_000962 3602436 3601012 -3 - 1425 Putative phosphotransferase - none - gi|15610361 fig|83332.1.peg.3229 CDS NC_000962 3603318 3602560 -3 - 759 putative bacteriophage protein - none - gi|15610362 fig|83332.1.peg.3230 CDS NC_000962 3603373 3604725 1 + 1353 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) # AroF Chorismate Synthesis;
Common Pathway For Synthesis of Aromatic Compounds (DAHP synthase to chorismate) gi|15610363 fig|83332.1.peg.3231 CDS NC_000962 3604722 3605714 3 + 993 Ribosome small subunit-stimulated GTPase EngC Universal GTPases gi|15610364 fig|83332.1.peg.3232 CDS NC_000962 3607030 3605747 -1 - 1284 POSSIBLE LINOLEOYL-CoA DESATURASE (DELTA(6)-DESATURASE) - none - gi|15610365 fig|83332.1.peg.3233 CDS NC_000962 3608250 3607108 -3 - 1143 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Anaerobic respiratory reductases gi|15610366 fig|83332.1.peg.3234 CDS NC_000962 3608869 3608360 -1 - 510 hypothetical protein Rv3231c - none - gi|15610367 fig|83332.1.peg.3235 CDS NC_000962 3609753 3608866 -3 - 888 Possible transcriptional regulatory protein PvdS, polyphosphate kinase 2 - none - gi|15610368 fig|83332.1.peg.3236 CDS NC_000962 3610367 3609777 -2 - 591 Wax ester synthase/acyl-CoA:diacylglycerol acyltransferase - none - gi|15610369 fig|83332.1.peg.3237 CDS NC_000962 3611185 3610370 -1 - 816 Diacyglycerol O-acyltransferase (EC 2.3.1.20) - none - gi|15610370 fig|83332.1.peg.3238 CDS NC_000962 3611296 3611937 1 + 642 FIG00820824: hypothetical protein - none - gi|15610371 fig|83332.1.peg.3239 CDS NC_000962 3613112 3611955 -2 - 1158 Kef-type K+ transport system, membrane component - none - gi|15610372 fig|83332.1.peg.3240 CDS NC_000962 3613599 3613117 -3 - 483 TrkA, Potassium channel - none - gi|15610373 fig|83332.1.peg.3241 CDS NC_000962 3614394 3613660 -3 - 735 Possible membrane protein - none - gi|15610374 fig|83332.1.peg.3242 CDS NC_000962 3617599 3614453 -1 - 3147 EmrB/QacA family drug resistance transporter - none - gi|15610375 fig|83332.1.peg.3243 CDS NC_000962 3620527 3617678 -1 - 2850 Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1) - none - gi|15610376 fig|83332.1.peg.3244 CDS NC_000962 3621250 3620606 -1 - 645 Ribosomal subunit interface protein Biotin biosynthesis Experimental;
Ribosome activity modulation gi|15610377 fig|83332.1.peg.3245 CDS NC_000962 3622207 3621566 -1 - 642 Competence protein F homolog, phosphoribosyltransferase domain; protein YhgH required for utilization of DNA as sole source of carbon and energy Biotin biosynthesis Experimental;
Biotin synthesis cluster gi|15610378 fig|83332.1.peg.3246 CDS NC_000962 3623087 3622245 -2 - 843 hypothetical protein - none - gi|15610379 fig|83332.1.peg.3247 CDS NC_000962 3624906 3623155 -3 - 1752 Lipoprotein LpqB - none - gi|15610380 fig|83332.1.peg.3248 CDS NC_000962 3626609 3624906 -2 - 1704 Sensor histidine kinase MtrB (EC 2.7.13.3) - none - gi|15610381 fig|83332.1.peg.3249 CDS NC_000962 3627345 3626659 -3 - 687 Two component sensory transduction transcriptional regulatory protein MtrA - none - gi|15610382 fig|83332.1.peg.3250 CDS NC_000962 3628059 3627415 -3 - 645 Thymidylate kinase (EC 2.7.4.9) pyrimidine conversions gi|15610383 fig|83332.1.peg.3251 CDS NC_000962 3629643 3628156 -3 - 1488 Adenosylhomocysteinase (EC 3.3.1.1) Methionine Biosynthesis;
Methionine Degradation gi|15610384 fig|83332.1.peg.3252 CDS NC_000962 3630383 3629748 -2 - 636 Transcriptional regulator, TetR family - none - gi|15610385 fig|83332.1.peg.3253 CDS NC_000962 3630562 3630380 -1 - 183 Rubredoxin Rubrerythrin gi|15610386 fig|83332.1.peg.3254 CDS NC_000962 3630734 3630567 -2 - 168 Rubredoxin Rubrerythrin gi|15610387 fig|83332.1.peg.3255 CDS NC_000962 3631984 3630734 -1 - 1251 Alkane-1 monooxygenase (EC 1.14.15.3) - none - gi|15610388 fig|83332.1.peg.3256 CDS NC_000962 3633580 3632093 -1 - 1488 Cationic amino acid transport integral membrane protein - none - gi|15610389 fig|83332.1.peg.3257 CDS NC_000962 3633671 3635059 2 + 1389 Putative oxidoreductase - none - gi|15610390 fig|83332.1.peg.3258 CDS NC_000962 3636263 3635037 -2 - 1227 Mannose-6-phosphate isomerase (EC 5.3.1.8) Mannose Metabolism gi|15610391 fig|83332.1.peg.3259 CDS NC_000962 3637311 3636271 -3 - 1041 hypothetical protein - none - gi|15610392 fig|83332.1.peg.3260 CDS NC_000962 3638705 3637308 -2 - 1398 Phosphomannomutase (EC 5.4.2.8) Mannose Metabolism gi|15610393 fig|83332.1.peg.3261 CDS NC_000962 3639298 3638807 -1 - 492 hypothetical protein Rv3258c - none - gi|15610394 fig|83332.1.peg.3262 CDS NC_000962 3639421 3639840 1 + 420 hypothetical protein Rv3259 - none - gi|15610395 fig|83332.1.peg.3263 CDS NC_000962 3640137 3639868 -3 - 270 Sporulation regulatory protein WhiB WhiB and WhiB-type regulatory proteins gi|15610396 fig|83332.1.peg.3264 CDS NC_000962 3640539 3641534 3 + 996 Lactyl (2) diphospho-(5')guanosine:7,8-didemethyl-8-hydroxy-5-deazariboflavin 2-phospho-L-lactate transferase Coenzyme F420 synthesis;
WhiB and WhiB-type regulatory proteins ;
dNTP triphosphohydrolase protein family gi|15610397 fig|83332.1.peg.3265 CDS NC_000962 3641531 3642877 2 + 1347 Coenzyme F420-0:L-glutamate ligase @ Coenzyme F420-1:L-glutamate ligase / domain of unknown function Coenzyme F420 synthesis;
Coenzyme F420 synthesis gi|15610398 fig|83332.1.peg.3266 CDS NC_000962 3643173 3644834 3 + 1662 DNA methylase - none - gi|15610399 fig|83332.1.peg.3267 CDS NC_000962 3645973 3644894 -1 - 1080 D-glycero-D-manno-heptose 1-phosphate guanosyltransferase Capsular heptose biosynthesis gi|15610400 fig|83332.1.peg.3268 CDS NC_000962 3646880 3645975 -2 - 906 dTDP-Rha:A-D-GlcNAc-diphosphoryl polyprenol, A-3-L-rhamnosyl transferase WbbL WhiB and WhiB-type regulatory proteins ;
dTDP-rhamnose synthesis gi|15610401 fig|83332.1.peg.3269 CDS NC_000962 3647805 3646891 -3 - 915 dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) Rhamnose containing glycans;
dTDP-rhamnose synthesis gi|15610402 fig|83332.1.peg.3270 CDS NC_000962 3647881 3649377 1 + 1497 Cell envelope-associated transcriptional attenuator LytR-CpsA-Psr, subfamily A1 (as in PMID19099556) Cell envelope-associated LytR-CpsA-Psr transcriptional attenuators gi|15610403 fig|83332.1.peg.3271 CDS NC_000962 3649416 3650105 3 + 690 hypothetical protein - none - gi|15610404 fig|83332.1.peg.3272 CDS NC_000962 3650230 3650511 1 + 282 hypothetical protein Rv3269 - none - gi|15610405 fig|83332.1.peg.3273 CDS NC_000962 3650522 3652678 2 + 2157 Probable cation-transporting P-type ATPase C (EC 3.6.3.-) (Metal-transporting ATPase Mta72) - none - gi|15610406 fig|83332.1.peg.3274 CDS NC_000962 3653343 3652675 -3 - 669 Possible membrane protein - none - gi|15610407 fig|83332.1.peg.3275 CDS NC_000962 3653444 3654628 2 + 1185 L-carnitine dehydratase/bile acid-inducible protein F (EC 2.8.3.16) - none - gi|15610408 fig|83332.1.peg.3276 CDS NC_000962 3654633 3656927 3 + 2295 Carbonic anhydrase (EC 4.2.1.1) - none - gi|15610409 fig|83332.1.peg.3277 CDS NC_000962 3658085 3656916 -2 - 1170 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4); Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.8.1) Isoleucine degradation gi|15610410 fig|83332.1.peg.3278 CDS NC_000962 3658634 3658110 -2 - 525 Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21) De Novo Purine Biosynthesis gi|15610411 fig|83332.1.peg.3279 CDS NC_000962 3659920 3658631 -1 - 1290 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) De Novo Purine Biosynthesis gi|15610412 fig|83332.1.peg.3280 CDS NC_000962 3659874 3660692 3 + 819 hypothetical protein - none - gi|15610413 fig|83332.1.peg.3281 CDS NC_000962 3661165 3660647 -1 - 519 hypothetical protein - none - gi|15610414 fig|83332.1.peg.3282 CDS NC_000962 3662008 3661208 -1 - 801 Biotin-protein ligase (EC 6.3.4.15) Biotin biosynthesis;
Biotin synthesis cluster;
Lipoic acid metabolism gi|15610415 fig|83332.1.peg.3283 CDS NC_000962 3662058 3663704 3 + 1647 Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4) HMG CoA Synthesis;
Leucine Degradation and HMG-CoA Metabolism;
Serine-glyoxylate cycle gi|15610416 fig|83332.1.peg.3284 CDS NC_000962 3663685 3664218 1 + 534 hypothetical protein - none - gi|15610417 fig|83332.1.peg.3285 CDS NC_000962 3664215 3664883 3 + 669 Septum formation protein Maf Bacterial Cell Division;
Bacterial Cytoskeleton gi|15610418 fig|83332.1.peg.3286 CDS NC_000962 3664924 3665817 1 + 894 Thiosulfate sulfurtransferase, rhodanese (EC 2.8.1.1) Single-Rhodanese-domain proteins gi|15610419 fig|83332.1.peg.3287 CDS NC_000962 3665814 3666245 3 + 432 Sulfur acceptor protein SufE for iron-sulfur cluster assembly - none - gi|15610420 fig|83332.1.peg.3288 CDS NC_000962 3666353 3668155 2 + 1803 Biotin carboxylase of acetyl-CoA carboxylase (EC 6.3.4.14) / Biotin carboxyl carrier protein of acetyl-CoA carboxylase Fatty Acid Biosynthesis FASII;
Fatty Acid Biosynthesis FASII gi|15610421 fig|83332.1.peg.3289 CDS NC_000962 3668950 3668165 -1 - 786 RNA polymerase sigma factor SigB SigmaB stress responce regulation;
Transcription initiation, bacterial sigma factors gi|15610422 fig|83332.1.peg.3291 CDS NC_000962 3669995 3669582 -2 - 414 Putative uncharacterized protein usfY - none - gi|15610424 fig|83332.1.peg.3292 CDS NC_000962 3670407 3670030 -3 - 378 Possible transmembrane protein - none - gi|15610425 fig|83332.1.peg.3293 CDS NC_000962 3671790 3670441 -3 - 1350 Probable L-lysine-epsilon aminotransferase (EC 2.6.1.36) (L-lysine aminotransferase) (Lysine 6-aminotransferase) - none - gi|15610426 fig|83332.1.peg.3294 CDS NC_000962 3672293 3671841 -2 - 453 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system Branched-Chain Amino Acid Biosynthesis;
Glutamine, Glutamate, Aspartate and Asparagine Biosynthesis gi|15610427 fig|83332.1.peg.3295 CDS NC_000962 3672324 3673571 3 + 1248 Uncharacterized protein Rv3292/MT3391 - none - gi|15610428 fig|83332.1.peg.3296 CDS NC_000962 3673598 3675082 2 + 1485 Aldehyde dehydrogenase B (EC 1.2.1.22) Glycerolipid and Glycerophospholipid Metabolism in Bacteria gi|15610429 fig|83332.1.peg.3297 CDS NC_000962 3675095 3675730 2 + 636 hypothetical protein Rv3294 - none - gi|15610430 fig|83332.1.peg.3298 CDS NC_000962 3676062 3676727 3 + 666 Transcriptional regulator, TetR family - none - gi|15610431 fig|83332.1.peg.3299 CDS NC_000962 3676771 3681312 1 + 4542 Probable ATP-dependent helicase lhr (EC 3.6.1.-) - none - gi|15610432 fig|83332.1.peg.3300 CDS NC_000962 3681316 3682083 1 + 768 Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23) - none - gi|15610433 fig|83332.1.peg.3301 CDS NC_000962 3683020 3682106 -1 - 915 Esterase lipoprotein LpqC - none - gi|15610434 fig|83332.1.peg.3302 CDS NC_000962 3685959 3683047 -3 - 2913 Arylsulfatase AtsB - none - gi|15610435 fig|83332.1.peg.3303 CDS NC_000962 3686896 3685979 -1 - 918 Ribosomal large subunit pseudouridine synthase A (EC 4.2.1.70) RNA pseudouridine syntheses;
Ribosome biogenesis bacterial gi|15610436 fig|83332.1.peg.3304 CDS NC_000962 3687573 3686908 -3 - 666 Phosphate transport system regulatory protein PhoU Glutathione analogs: mycothiol;
High affinity phosphate transporter and control of PHO regulon;
Phosphate metabolism gi|15610437 fig|83332.1.peg.3305 CDS NC_000962 3689438 3687681 -2 - 1758 Glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) Glycerol and Glycerol-3-phosphate Uptake and Utilization;
Glycerolipid and Glycerophospholipid Metabolism in Bacteria;
Respiratory dehydrogenases 1 gi|15610438 fig|83332.1.peg.3306 CDS NC_000962 3690934 3689453 -1 - 1482 Dihydrolipoamide dehydrogenase (EC 1.8.1.4) Dehydrogenase complexes;
Glycine cleavage system;
TCA Cycle gi|15610439 fig|83332.1.peg.3307 CDS NC_000962 3691137 3691616 3 + 480 Putative uncharacterized protein BCG_3369 - none - gi|15610440 fig|83332.1.peg.3308 CDS NC_000962 3692804 3691635 -2 - 1170 Possible N-acyl-L-amino acid amidohydrolase amiA1 (EC 3.5.1.-) - none - gi|15610441 fig|83332.1.peg.3309 CDS NC_000962 3693985 3692801 -1 - 1185 N-acyl-L-amino acid amidohydrolase (EC 3.5.1.14) - none - gi|15610442 fig|83332.1.peg.3310 CDS NC_000962 3694050 3694856 3 + 807 Purine nucleoside phosphorylase (EC 2.4.2.1) Adenosyl nucleosidases;
Deoxyribose and Deoxynucleoside Catabolism;
Purine conversions;
pyrimidine conversions gi|15610443 fig|83332.1.peg.3311 CDS NC_000962 3694860 3696464 3 + 1605 Phosphomannomutase (EC 5.4.2.8) - none - gi|15610444 fig|83332.1.peg.3312 CDS NC_000962 3697089 3696466 -3 - 624 Uracil phosphoribosyltransferase (EC 2.4.2.9) De Novo Pyrimidine Synthesis;
pyrimidine conversions gi|15610445 fig|83332.1.peg.3313 CDS NC_000962 3697194 3698093 3 + 900 Possible acid phosphatase (EC 3.1.3.2) - none - gi|15610446 fig|83332.1.peg.3314 CDS NC_000962 3698117 3699379 2 + 1263 Putative uncharacterized protein BCG_3376 - none - gi|15610447 fig|83332.1.peg.3315 CDS NC_000962 3700326 3699400 -3 - 927 Hydrolase, alpha/beta hydrolase fold family - none - gi|15610448 fig|83332.1.peg.3316 CDS NC_000962 3702180 3701083 -3 - 1098 Adenosine deaminase (EC 3.5.4.4) Purine conversions gi|15610449 fig|83332.1.peg.3317 CDS NC_000962 3703463 3702180 -2 - 1284 Thymidine phosphorylase (EC 2.4.2.4) Deoxyribose and Deoxynucleoside Catabolism;
pyrimidine conversions gi|15610450 fig|83332.1.peg.3318 CDS NC_000962 3703861 3703460 -1 - 402 Cytidine deaminase (EC 3.5.4.5) pyrimidine conversions;
tRNA modification Bacteria gi|15610451 fig|83332.1.peg.3319 CDS NC_000962 3704098 3704436 1 + 339 Succinate dehydrogenase cytochrome b-556 subunit Succinate dehydrogenase gi|15610452 fig|83332.1.peg.3320 CDS NC_000962 3704433 3704867 3 + 435 Succinate dehydrogenase hydrophobic membrane anchor protein Succinate dehydrogenase gi|15610453 fig|83332.1.peg.3321 CDS NC_000962 3704996 3706768 2 + 1773 Succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1) Serine-glyoxylate cycle;
Succinate dehydrogenase;
TCA Cycle gi|15610454 fig|83332.1.peg.3322 CDS NC_000962 3706768 3707559 1 + 792 Succinate dehydrogenase iron-sulfur protein (EC 1.3.99.1) 5-FCL-like protein;
Serine-glyoxylate cycle;
Succinate dehydrogenase;
TCA Cycle gi|15610455 fig|83332.1.peg.3323 CDS NC_000962 3708066 3707638 -3 - 429 Toxin 1, PIN domain Toxin-Antitoxin MT1 gi|15610456 fig|83332.1.peg.3324 CDS NC_000962 3708312 3708070 -3 - 243 Antitoxin 1 Toxin-Antitoxin MT1 gi|15610457 fig|83332.1.peg.3325 CDS NC_000962 3709048 3708434 -1 - 615 Possible methyltransferase (EC 2.1.1.-) - none - gi|15610458 fig|83332.1.peg.3326 CDS NC_000962 3709710 3709045 -3 - 666 Molybdenum cofactor biosynthesis protein MoaD / Molybdenum cofactor biosynthesis protein MoaE Molybdenum cofactor biosynthesis;
Molybdenum cofactor biosynthesis;
ar-104-EC Molybdenum cofactor biosynthesis moaABCDE;
ar-104-EC Molybdenum cofactor biosynthesis moaABCDE gi|15610459 fig|83332.1.peg.3327 CDS NC_000962 3710244 3709711 -3 - 534 Molybdenum cofactor biosynthesis protein MoaC Molybdenum cofactor biosynthesis;
ar-104-EC Molybdenum cofactor biosynthesis moaABCDE gi|15610460 fig|83332.1.peg.3328 CDS NC_000962 3710429 3710755 2 + 327 Mobile element protein - none - gi|15610461 fig|83332.1.peg.3329 CDS NC_000962 3710752 3711690 1 + 939 Mobile element protein - none - gi|15610462 fig|83332.1.peg.3330 CDS NC_000962 3711745 3713457 1 + 1713 hypothetical protein Rv3327 - none - gi|15610463 fig|83332.1.peg.3331 CDS NC_000962 3714328 3713390 -1 - 939 RNA polymerase sigma factor SigJ - none - gi|15610464 fig|83332.1.peg.3332 CDS NC_000962 3714388 3715704 1 + 1317 Omega-amino acid--pyruvate aminotransferase (EC 2.6.1.18) - none - gi|15610465 fig|83332.1.peg.3333 CDS NC_000962 3715773 3716990 3 + 1218 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) CBSS-84588.1.peg.1247;
Metallocarboxypeptidases (EC 3.4.17.-);
Murein Hydrolases;
Peptidoglycan Biosynthesis gi|15610466 fig|83332.1.peg.3334 CDS NC_000962 3717086 3718594 2 + 1509 Sugar-transport integral membrane proteinSugI - none - gi|15610467 fig|83332.1.peg.3335 CDS NC_000962 3718591 3719742 1 + 1152 N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25) Chitin and N-acetylglucosamine utilization;
UDP-N-acetylmuramate from Fructose-6-phosphate Biosynthesis gi|15610468 fig|83332.1.peg.3336 CDS NC_000962 3720778 3719933 -1 - 846 Hydroxyproline-rich glycoprotein DZ-HRGP precursor - none - gi|15610469 fig|83332.1.peg.3337 CDS NC_000962 3721253 3721693 2 + 441 Mercuric resistance operon regulatory protein - none - gi|15610470 fig|83332.1.peg.3338 CDS NC_000962 3722596 3721727 -1 - 870 Possible membrane protein - none - gi|15610471 fig|83332.1.peg.3339 CDS NC_000962 3723627 3722617 -3 - 1011 Tryptophanyl-tRNA synthetase (EC 6.1.1.2) tRNA aminoacylation, Trp gi|15610472 fig|83332.1.peg.3340 CDS NC_000962 3723652 3723894 1 + 243 hypothetical protein Rv3337 - none - gi|15610473 fig|83332.1.peg.3341 CDS NC_000962 3723900 3724544 3 + 645 Alpha/beta hydrolase family - none - gi|15610474 fig|83332.1.peg.3342 CDS NC_000962 3725840 3724611 -2 - 1230 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42) 5-FCL-like protein;
TCA Cycle gi|15610475 fig|83332.1.peg.3343 CDS NC_000962 3726123 3727472 3 + 1350 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) Methionine Biosynthesis;
Methionine Biosynthesis gi|15610476 fig|83332.1.peg.3344 CDS NC_000962 3727484 3728623 2 + 1140 Homoserine O-acetyltransferase (EC 2.3.1.31) Methionine Biosynthesis gi|15610477 fig|83332.1.peg.3345 CDS NC_000962 3728620 3729351 1 + 732 Methyltransferase (EC 2.1.1.-) - none - gi|15610478 fig|83332.1.peg.3346 CDS NC_000962 3736931 3729360 -2 - 7572 PPE family protein - none - gi|15610479 fig|83332.1.peg.3347 CDS NC_000962 3738434 3736980 -2 - 1455 Protein sequence is in conflict with the conceptual translation; (MTV016.44c), len: 484. Member of the M. tuberculosis PE-PGRS group of Gly, Ala-rich proteins. Appears to be a gene fragment, should be in-frame with following orf, MTV016.45c, frameshift required around 49595 but couldnot be found on checking BAC and cosmid clones. FASTA scores: Z95844|MTCY493_4 Mycobacterium tuberculosis cosmid (1329 aa) opt: 1457 z-score: 821.7 E(): 0; 50.5% identity in 531 aa overlap. TBparse score is 0.831 - none - gi|15610480 fig|83332.1.peg.3348 CDS NC_000962 3742770 3738154 -3 - 4617 PE family protein - none - gi|15610481 fig|83332.1.peg.3349 CDS NC_000962 3743451 3743194 -3 - 258 FIG00824674: hypothetical protein - none - gi|15610482 fig|83332.1.peg.3350 CDS NC_000962 3753180 3743707 -3 - 9474 (MTV004.03c), member of the M. tuberculosis PPE family of Gly-, Ala-, Asn-rich proteins), len: 3157 aa; similar to many eg. TR:O07232 (EMBL:Z96800) MTCY63.10c (963 aa), opt: 1181 z-score: 2191.5 E(): 0, 47.5% identity in 995 aa overlap. Also similar to upstream ORF MTV004_5, MTY13E10_15, MTCY28_16, MTCY63_9,MTY13E10_17, MTCY180_1 etc. - none - gi|15610483 fig|83332.1.peg.3351 CDS NC_000962 3753761 3754252 2 + 492 Mobile element protein - none - gi|15610484 fig|83332.1.peg.3352 CDS NC_000962 3755029 3754289 -1 - 741 Mobile element protein - none - gi|15610485 fig|83332.1.peg.3353 CDS NC_000962 3767098 3755948 -1 - 11151 (MTV004.07c), len: 3716, member of the M. tuberculosis PPE family of Gly-, Ala-, Asn-rich proteins, similar to many eg. Y04H_MYCTU Q10778 MTCY48.17 (734 aa), fasta scores; opt: 1264 z-score: 1136.3 E(): 0, 47.4% identity in 546 aa overlap. Also similar to MTV004_3, MTCY28_16, MTV050_2, MTY13E10_17, MTCY63_10, MTCY180_1, MTCY63_9, MTV050_1, MTV014_3, MTY13E10_15 etc. - none - gi|15610486 fig|83332.1.peg.3354 CDS NC_000962 3768136 3767342 -1 - 795 hypothetical protein Rv3351c - none - gi|15610487 fig|83332.1.peg.3355 CDS NC_000962 3768589 3768218 -1 - 372 hypothetical protein Rv3352c - none - gi|15610488 fig|83332.1.peg.3356 CDS NC_000962 3769076 3768732 -2 - 345 hypothetical protein Rv3353c - none - gi|15610489 fig|83332.1.peg.3357 CDS NC_000962 3769107 3769496 3 + 390 Possible lipoprotein LprJ - none - gi|15610490 fig|83332.1.peg.3358 CDS NC_000962 3769803 3769510 -3 - 294 FIG00824674: hypothetical protein - none - gi|15610491 fig|83332.1.peg.3359 CDS NC_000962 3770645 3769800 -2 - 846 Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) Folate Biosynthesis;
One-carbon metabolism by tetrahydropterines;
One-carbon metabolism by tetrahydropterines;
Serine-glyoxylate cycle;
Serine-glyoxylate cycle gi|15610492 fig|83332.1.peg.3360 CDS NC_000962 3770769 3771044 3 + 276 YefM protein (antitoxin to YoeB) Toxin-antitoxin replicon stabilization systems gi|15610493 fig|83332.1.peg.3361 CDS NC_000962 3771041 3771298 2 + 258 YoeB toxin protein Toxin-antitoxin replicon stabilization systems gi|15610494 fig|83332.1.peg.3362 CDS NC_000962 3771340 3772530 1 + 1191 NADH:flavin oxidoreductases, Old Yellow Enzyme family - none - gi|15610495 fig|83332.1.peg.3363 CDS NC_000962 3772647 3773015 3 + 369 ABC transporter ATP-binding protein - none - gi|15610496 fig|83332.1.peg.3364 CDS NC_000962 3773563 3773012 -1 - 552 Pentapeptide repeat family protein - none - gi|15610497 fig|83332.1.peg.3365 CDS NC_000962 3774151 3773570 -1 - 582 Putative ATP/GTP-binding protein - none - gi|15610498 fig|83332.1.peg.3366 CDS NC_000962 3774500 3774132 -2 - 369 hypothetical protein Rv3363c - none - gi|15610499 fig|83332.1.peg.3367 CDS NC_000962 3774870 3774478 -3 - 393 hypothetical protein Rv3364c - none - gi|15610500 fig|83332.1.peg.3368 CDS NC_000962 3777497 3774867 -2 - 2631 Putative sensor-like histidine kinase - none - gi|15610501 fig|83332.1.peg.3369 CDS NC_000962 3777733 3778197 1 + 465 tRNA (cytidine(34)-2'-O)-methyltransferase (EC 2.1.1.207) ## TrmL Biotin biosynthesis Experimental;
Biotin synthesis cluster;
Glutaredoxins;
RNA methylation;
tRNA modification Bacteria gi|15610502 fig|83332.1.peg.3370 CDS NC_000962 3778564 3780330 1 + 1767 PE family protein - none - gi|15610503 fig|83332.1.peg.3371 CDS NC_000962 3780975 3780331 -3 - 645 Nitroreductase family - none - gi|15610504 fig|83332.1.peg.3372 CDS NC_000962 3780974 3781408 2 + 435 hypothetical protein Rv3369 - none - gi|15610505 fig|83332.1.peg.3373 CDS NC_000962 3784736 3781497 -2 - 3240 DNA polymerase III alpha subunit (EC 2.7.7.7) CBSS-350688.3.peg.1509;
DNA replication strays gi|15610506 fig|83332.1.peg.3374 CDS NC_000962 3784928 3786268 2 + 1341 Diacyglycerol O-acyltransferase (EC 2.3.1.20) - none - gi|15610507 fig|83332.1.peg.3375 CDS NC_000962 3786310 3787485 1 + 1176 Trehalose-6-phosphate phosphatase (EC 3.1.3.12) Trehalose Biosynthesis gi|15610508 fig|83332.1.peg.3376 CDS NC_000962 3787722 3788363 3 + 642 Enoyl-CoA hydratase (EC 4.2.1.17) Acetyl-CoA fermentation to Butyrate;
Fatty acid metabolism cluster gi|15610509 fig|83332.1.peg.3377 CDS NC_000962 3788364 3788612 3 + 249 Enoyl-CoA hydratase (EC 4.2.1.17) # frameshift - none - gi|15610510 fig|83332.1.peg.3378 CDS NC_000962 3788617 3790044 1 + 1428 Glutamyl-tRNA(Gln) amidotransferase subunit A-like protein tRNA aminoacylation, Glu and Gln gi|15610511 fig|83332.1.peg.3379 CDS NC_000962 3790152 3790805 3 + 654 Hydrolase, haloacid dehalogenase-like family - none - gi|15610512 fig|83332.1.peg.3380 CDS NC_000962 3792349 3790844 -1 - 1506 Ent-copalyl diphosphate synthase - none - gi|15610513 fig|83332.1.peg.3381 CDS NC_000962 3793244 3792354 -2 - 891 FIG00820088: hypothetical protein - none - gi|15610514 fig|83332.1.peg.3382 CDS NC_000962 3794863 3793253 -1 - 1611 1-deoxy-D-xylulose 5-phosphate synthase (EC 2.2.1.7) Isoprenoid Biosynthesis;
Nonmevalonate Branch of Isoprenoid Biosynthesis;
Pyridoxin (Vitamin B6) Biosynthesis;
Thiamin biosynthesis gi|15610515 fig|83332.1.peg.3383 CDS NC_000962 3795980 3795096 -2 - 885 Mobile element protein - none - gi|15610516 fig|83332.1.peg.3384 CDS NC_000962 3796357 3796031 -1 - 327 Mobile element protein - none - gi|15610517 fig|83332.1.peg.3385 CDS NC_000962 3797433 3796444 -3 - 990 4-hydroxy-3-methylbut-2-enyl diphosphate reductase (EC 1.17.1.2) Isoprenoid Biosynthesis;
Nonmevalonate Branch of Isoprenoid Biosynthesis gi|15610518 fig|83332.1.peg.3386 CDS NC_000962 3798485 3797433 -2 - 1053 Octaprenyl diphosphate synthase (EC 2.5.1.90) / Dimethylallyltransferase (EC 2.5.1.1) / (2E,6E)-farnesyl diphosphate synthase (EC 2.5.1.10) / Geranylgeranyl diphosphate synthase (EC 2.5.1.29) Carotenoids;
Carotenoids;
Isoprenoid Biosynthesis;
Isoprenoid Biosynthesis;
Isoprenoid Biosynthesis: Interconversions;
Isoprenoinds for Quinones;
Isoprenoinds for Quinones;
Isoprenoinds for Quinones;
Isoprenoinds for Quinones;
Polyprenyl Diphosphate Biosynthesis;
Polyprenyl Diphosphate Biosynthesis;
Polyprenyl Diphosphate Biosynthesis gi|15610519 fig|83332.1.peg.3387 CDS NC_000962 3799631 3799239 -2 - 393 hypothetical protein Rv3384c - none - gi|15610520 fig|83332.1.peg.3388 CDS NC_000962 3799939 3799631 -1 - 309 hypothetical protein Rv3385c - none - gi|15610521 fig|83332.1.peg.3389 CDS NC_000962 3800088 3800792 3 + 705 Mobile element protein - none - gi|15610522 fig|83332.1.peg.3390 CDS NC_000962 3800782 3801459 1 + 678 Mobile element protein - none - gi|15610523 fig|83332.1.peg.3391 CDS NC_000962 3801649 3803844 1 + 2196 PE family protein - none - gi|15610524 fig|83332.1.peg.3392 CDS NC_000962 3804787 3803915 -1 - 873 Enoyl-CoA hydratase - none - gi|15610525 fig|83332.1.peg.3393 CDS NC_000962 3804861 3805571 3 + 711 Lipoprotein LpqD - none - gi|15610526 fig|83332.1.peg.3394 CDS NC_000962 3805617 3807569 3 + 1953 Oxidoreductase, short-chain dehydrogenase/reductase family - none - gi|15610527 fig|83332.1.peg.3395 CDS NC_000962 3808433 3807570 -2 - 864 Cyclopropane-fatty-acyl-phospholipid synthase 1, CmaA1 (EC 2.1.1.79) - none - gi|15610528 fig|83332.1.peg.3396 CDS NC_000962 3808457 3809383 2 + 927 Inosine-uridine preferring nucleoside hydrolase (EC 3.2.2.1) Purine conversions gi|15610529 fig|83332.1.peg.3397 CDS NC_000962 3811021 3809438 -1 - 1584 DNA polymerase IV-like protein ImuB DNA repair, bacterial;
DNA replication strays gi|15610530 fig|83332.1.peg.3398 CDS NC_000962 3811902 3811018 -3 - 885 FIG00821108: hypothetical protein - none - gi|15610531 fig|83332.1.peg.3399 CDS NC_000962 3814074 3812497 -3 - 1578 GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) GMP synthase;
GMP synthase;
Purine conversions gi|15610532 fig|83332.1.peg.3400 CDS NC_000962 3814994 3814086 -2 - 909 Phytoene synthase (EC 2.5.1.32) Carotenoids gi|15610533 fig|83332.1.peg.3401 CDS NC_000962 3816102 3815023 -3 - 1080 Dimethylallyltransferase (EC 2.5.1.1); (2E,6E)-farnesyl diphosphate synthase (EC 2.5.1.10); Geranylgeranyl diphosphate synthase (EC 2.5.1.29) Carotenoids;
Carotenoids;
Isoprenoid Biosynthesis;
Isoprenoid Biosynthesis;
Isoprenoid Biosynthesis: Interconversions;
Isoprenoinds for Quinones;
Isoprenoinds for Quinones;
Isoprenoinds for Quinones;
Polyprenyl Diphosphate Biosynthesis;
Polyprenyl Diphosphate Biosynthesis gi|15610534 fig|83332.1.peg.3402 CDS NC_000962 3816125 3817171 2 + 1047 Putative S-adenosyl-L-methionine-dependent methyltransferase (EC 2.1.1.-) - none - gi|15610535 fig|83332.1.peg.3403 CDS NC_000962 3817235 3818023 2 + 789 Hydrolase, haloacid dehalogenase-like family - none - gi|15610536 fig|83332.1.peg.3404 CDS NC_000962 3818038 3820398 1 + 2361 Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64) Maltose and Maltodextrin Utilization;
Trehalose Biosynthesis;
Trehalose Uptake and Utilization gi|15610537 fig|83332.1.peg.3405 CDS NC_000962 3821887 3820649 -1 - 1239 DegT/DnrJ/EryC1 family protein - none - gi|15610538 fig|83332.1.peg.3406 CDS NC_000962 3823859 3822258 -2 - 1602 FIG034901: hypothetical protein - none - gi|15610539 fig|83332.1.peg.3407 CDS NC_000962 3824580 3823876 -3 - 705 Methionyl-tRNA formyltransferase - none - gi|15610540 fig|83332.1.peg.3408 CDS NC_000962 3825264 3824698 -3 - 567 Transcriptional regulator, TetR family - none - gi|15610541 fig|83332.1.peg.3409 CDS NC_000962 3825326 3826213 2 + 888 Alpha-ketoglutarate-dependent taurine dioxygenase (EC 1.14.11.17) - none - gi|15610542 fig|83332.1.peg.3410 CDS NC_000962 3826248 3826547 3 + 300 hypothetical protein Rv3407 - none - gi|15610543 fig|83332.1.peg.3411 CDS NC_000962 3826544 3826954 2 + 411 hypothetical protein Rv3408 - none - gi|15610544 fig|83332.1.peg.3412 CDS NC_000962 3828723 3826987 -3 - 1737 Cholesterol oxidase (EC 1.1.3.6) - none - gi|15610545 fig|83332.1.peg.3413 CDS NC_000962 3829906 3828779 -1 - 1128 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) Purine conversions;
Purine salvage cluster gi|15610546 fig|83332.1.peg.3414 CDS NC_000962 3831515 3829926 -2 - 1590 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain Purine conversions;
Purine salvage cluster;
Purine salvage cluster;
WhiB and WhiB-type regulatory proteins gi|15610547 fig|83332.1.peg.3415 CDS NC_000962 3831722 3832132 2 + 411 hypothetical protein - none - gi|15610548 fig|83332.1.peg.3416 CDS NC_000962 3833041 3832142 -1 - 900 FIG00821001: hypothetical protein - none - gi|15610549 fig|83332.1.peg.3417 CDS NC_000962 3833672 3833034 -2 - 639 RNA polymerase sigma-D factor - none - gi|15610550 fig|83332.1.peg.3418 CDS NC_000962 3834517 3833690 -1 - 828 FIG00822851: hypothetical protein - none - gi|15610551 fig|83332.1.peg.3419 CDS NC_000962 3834888 3835196 3 + 309 Sporulation regulatory protein WhiD WhiB and WhiB-type regulatory proteins gi|15610552 fig|83332.1.peg.3420 CDS NC_000962 3836887 3835268 -1 - 1620 Heat shock protein 60 family chaperone GroEL GroEL GroES gi|15610553 fig|83332.1.peg.3421 CDS NC_000962 3837284 3836982 -2 - 303 Heat shock protein 60 family co-chaperone GroES GroEL GroES gi|15610554 fig|83332.1.peg.3422 CDS NC_000962 3838585 3837551 -1 - 1035 TsaD/Kae1/Qri7 protein, required for threonylcarbamoyladenosine t(6)A37 formation in tRNA Bacterial RNA-metabolizing Zn-dependent hydrolases;
Conserved gene cluster associated with Met-tRNA formyltransferase;
Macromolecular synthesis operon;
YgjD and YeaZ;
YrdC-YciO-Sua5 protein family gi|15610555 fig|83332.1.peg.3423 CDS NC_000962 3839058 3838582 -3 - 477 Ribosomal-protein-S18p-alanine acetyltransferase (EC 2.3.1.-) Bacterial RNA-metabolizing Zn-dependent hydrolases;
Conserved gene cluster associated with Met-tRNA formyltransferase;
Ribosome biogenesis bacterial;
YrdC-YciO-Sua5 protein family gi|15610556 fig|83332.1.peg.3424 CDS NC_000962 3839690 3839055 -2 - 636 TsaB protein, required for threonylcarbamoyladenosine (t(6)A) formation in tRNA Bacterial RNA-metabolizing Zn-dependent hydrolases;
Conserved gene cluster associated with Met-tRNA formyltransferase;
Ribosome biogenesis bacterial;
YgjD and YeaZ;
YjeE;
YrdC-YciO-Sua5 protein family gi|15610557 fig|83332.1.peg.3425 CDS NC_000962 3840193 3839687 -1 - 507 TsaE protein, required for threonylcarbamoyladenosine t(6)A37 formation in tRNA Cell envelope-associated LytR-CpsA-Psr transcriptional attenuators;
YjeE;
YrdC-YciO-Sua5 protein family gi|15610558 fig|83332.1.peg.3426 CDS NC_000962 3841416 3840190 -3 - 1227 Alanine racemase (EC 5.1.1.1) Alanine biosynthesis;
Pyruvate Alanine Serine Interconversions;
YrdC-YciO-Sua5 protein family gi|15610559 fig|83332.1.peg.3427 CDS NC_000962 3842072 3841710 -2 - 363 hypothetical protein Rv3424c - none - gi|15610560 fig|83332.1.peg.3428 CDS NC_000962 3842235 3842765 3 + 531 PPE family protein - none - gi|15610561 fig|83332.1.peg.3429 CDS NC_000962 3843032 3843730 2 + 699 (MTCY78.03c), len: 232, unknown, similar toPPE_family, e.g. YHS6_MYCTU P42611 hypothetical 50.6 kd protein in hsp65 (517 aa) fasta scores, opt: 197, z-score:217.5, E(): 3.6e-05, (29.6% identity in 152 aa overlap), alsosimilar to upstream Rv3425 MTCY78.04c (68.0 % identity in125 aa overlap), downstream Rv3429 MTCY77_1, MTV049_30, MTCY3C7_24, MTCY428_16, MTCY3A2_22, etc. - none - gi|15610562 fig|83332.1.peg.3430 CDS NC_000962 3844636 3843881 -1 - 756 Mobile element protein - none - gi|15610563 fig|83332.1.peg.3431 CDS NC_000962 3845966 3844734 -2 - 1233 Mobile element protein - none - gi|15610564 fig|83332.1.peg.3432 CDS NC_000962 3847161 3847697 3 + 537 PPE family protein - none - gi|15610565 fig|83332.1.peg.3433 CDS NC_000962 3848801 3847638 -2 - 1164 Mobile element protein - none - gi|15610566 fig|83332.1.peg.3434 CDS NC_000962 3850135 3849290 -1 - 846 Mobile element protein - none - gi|15610567 fig|83332.1.peg.3435 CDS NC_000962 3851750 3850368 -2 - 1383 Glutamate decarboxylase (EC 4.1.1.15) - none - gi|15610568 fig|83332.1.peg.3436 CDS NC_000962 3853209 3851788 -3 - 1422 NAD(P)HX epimerase / NAD(P)HX dehydratase YjeE;
YjeE gi|15610569 fig|83332.1.peg.3437 CDS NC_000962 3853924 3853211 -1 - 714 Possible membrane protein - none - gi|15610570 fig|83332.1.peg.3438 CDS NC_000962 3854789 3853935 -2 - 855 Possible membrane protein - none - gi|15610571 fig|83332.1.peg.3439 CDS NC_000962 3856885 3855011 -1 - 1875 Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) Inteins;
UDP-N-acetylmuramate from Fructose-6-phosphate Biosynthesis gi|15610572 fig|83332.1.peg.3440 CDS NC_000962 3856907 3857383 2 + 477 Possible membrane protein - none - gi|15610573 fig|83332.1.peg.3441 CDS NC_000962 3857393 3858235 2 + 843 hypothetical protein Rv3438 - none - gi|15610574 fig|83332.1.peg.3442 CDS NC_000962 3859658 3858255 -2 - 1404 Conserved alanine and proline rich protein - none - gi|15610575 fig|83332.1.peg.3443 CDS NC_000962 3859972 3859661 -1 - 312 hypothetical protein Rv3440c - none - gi|15610576 fig|83332.1.peg.3444 CDS NC_000962 3861366 3860020 -3 - 1347 Phosphoglucosamine mutase (EC 5.4.2.10) UDP-N-acetylmuramate from Fructose-6-phosphate Biosynthesis gi|15610577 fig|83332.1.peg.3445 CDS NC_000962 3861946 3861491 -1 - 456 SSU ribosomal protein S9p (S16e) Ribosome SSU bacterial gi|15610578 fig|83332.1.peg.3446 CDS NC_000962 3862386 3861943 -3 - 444 LSU ribosomal protein L13p (L13Ae) Ribosome LSU bacterial gi|15610579 fig|83332.1.peg.3447 CDS NC_000962 3862922 3862620 -2 - 303 ESAT-6 like protein EsxT - none - gi|15610580 fig|83332.1.peg.3448 CDS NC_000962 3863320 3862943 -1 - 378 ESAT-6 like protein EsxU - none - gi|15610581 fig|83332.1.peg.3449 CDS NC_000962 3864527 3863313 -2 - 1215 Type VII secretion-associated protein - none - gi|15610582 fig|83332.1.peg.3450 CDS NC_000962 3868234 3864524 -1 - 3711 Type VII secretion protein EccCb / Type VII secretion protein EssC - none - gi|15610583 fig|83332.1.peg.3451 CDS NC_000962 3868348 3869751 1 + 1404 hypothetical protein Rv3448 - none - gi|15610584 fig|83332.1.peg.3452 CDS NC_000962 3869748 3871115 3 + 1368 hypothetical protein Rv3449 - none - gi|15610585 fig|83332.1.peg.3453 CDS NC_000962 3872492 3871080 -2 - 1413 hypothetical protein Rv3450c - none - gi|15610586 fig|83332.1.peg.3454 CDS NC_000962 3872658 3873401 3 + 744 Probable cutinase Cut3 (EC 3.1.1.74) - none - gi|15610587 fig|83332.1.peg.3455 CDS NC_000962 3873448 3874128 1 + 681 Probable cutinase Cut4 - none - gi|15610588 fig|83332.1.peg.3456 CDS NC_000962 3874400 3874732 2 + 333 hypothetical protein Rv3453 - none - gi|15610589 fig|83332.1.peg.3457 CDS NC_000962 3874818 3876086 3 + 1269 Possible membrane protein - none - gi|15610590 fig|83332.1.peg.3458 CDS NC_000962 3876818 3876048 -2 - 771 tRNA pseudouridine synthase A (EC 4.2.1.70) RNA pseudouridine syntheses;
tRNA modification Bacteria;
tRNA processing gi|15610591 fig|83332.1.peg.3459 CDS NC_000962 3877428 3876886 -3 - 543 LSU ribosomal protein L17p Ribosome LSU bacterial gi|15610592 fig|83332.1.peg.3460 CDS NC_000962 3878503 3877460 -1 - 1044 DNA-directed RNA polymerase alpha subunit (EC 2.7.7.6) RNA polymerase bacterial gi|15610593 fig|83332.1.peg.3461 CDS NC_000962 3879260 3878655 -2 - 606 SSU ribosomal protein S4p (S9e) Ribosome SSU bacterial gi|15610594 fig|83332.1.peg.3462 CDS NC_000962 3879688 3879269 -1 - 420 SSU ribosomal protein S11p (S14e) Ribosome SSU bacterial gi|15610595 fig|83332.1.peg.3463 CDS NC_000962 3880066 3879692 -1 - 375 SSU ribosomal protein S13p (S18e) Ribosome SSU bacterial gi|15610596 fig|83332.1.peg.3464 CDS NC_000962 3880395 3880282 -3 - 114 LSU ribosomal protein L36p Ribosome LSU bacterial gi|15610597 fig|83332.1.peg.3465 CDS NC_000962 3880649 3880428 -2 - 222 Translation initiation factor 1 Translation initiation factors bacterial gi|15610598 fig|83332.1.peg.3466 CDS NC_000962 3880903 3881760 1 + 858 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - none - gi|15610599 fig|83332.1.peg.3467 CDS NC_000962 3881833 3882828 1 + 996 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) Rhamnose containing glycans;
dTDP-rhamnose synthesis gi|15610600 fig|83332.1.peg.3468 CDS NC_000962 3882830 3883438 2 + 609 dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) Capsular heptose biosynthesis;
Rhamnose containing glycans;
dTDP-rhamnose synthesis gi|15610601 fig|83332.1.peg.3469 CDS NC_000962 3883521 3884189 3 + 669 hypothetical protein Rv3466 - none - gi|15610602 fig|83332.1.peg.3470 CDS NC_000962 3883960 3884913 1 + 954 hypothetical protein Rv3467 - none - gi|15610603 fig|83332.1.peg.3471 CDS NC_000962 3886065 3884971 -3 - 1095 UDP-glucose 4-epimerase (EC 5.1.3.2) - none - gi|15610604 fig|83332.1.peg.3472 CDS NC_000962 3887079 3886069 -3 - 1011 4-hydroxy-2-oxovalerate aldolase (EC 4.1.3.39) Biphenyl Degradation gi|15610605 fig|83332.1.peg.3473 CDS NC_000962 3888798 3887140 -3 - 1659 Acetohydroxy acid synthase - none - gi|15610606 fig|83332.1.peg.3474 CDS NC_000962 3889337 3888804 -2 - 534 Mannose-6-phosphate isomerase - none - gi|15610607 fig|83332.1.peg.3475 CDS NC_000962 3889358 3889864 2 + 507 hypothetical protein Rv3472 - none - gi|15610608 fig|83332.1.peg.3476 CDS NC_000962 3890729 3889944 -2 - 786 Hydrolase, alpha/beta fold family - none - gi|15610609 fig|83332.1.peg.3477 CDS NC_000962 3890826 3891152 3 + 327 Mobile element protein - none - gi|15610610 fig|83332.1.peg.3478 CDS NC_000962 3891047 3892087 2 + 1041 Mobile element protein - none - gi|15610611 fig|83332.1.peg.3479 CDS NC_000962 3893716 3892367 -1 - 1350 Dicarboxylic acid transport integral membrane protein KgtP - none - gi|15610612 fig|83332.1.peg.3480 CDS NC_000962 3894089 3894385 2 + 297 (MTCY13E12.30), len: 98. Member of M. tuberculosis PE family including MTCI364.07, MTCY21C12.10c, MTCY1A11.25c, MTC1A11.04, MTCY359.33 etc. (PE class). FASTA results: sp|O05297|O05297 HYPOTHETICAL 9.6 KD PROTEIN (99 aa)opt: 394 z-score: 508.4 E(): 8.5e-21; 71.6% identity in 95 aa overlap - none - gi|15610613 fig|83332.1.peg.3481 CDS NC_000962 3894422 3895603 2 + 1182 (MTCY13E12.31), len: 393. Member of M. tuberculosis PPE family. Includes MTCY02B10.25c, MTCI364.08, MTCY10G2.10, MTCY03A2.22c, MTCY274.23c, MTCY164.34c, MTCY98.0029c, etc. FASTA scores: Z75555|MTCY02B10_25 Mycobacterium tuberculosis cosm (396 aa) opt: 2165 z-score: 2221.1 E():0; 85.4% identity in 396 aa overlap - none - gi|15610614 fig|83332.1.peg.3482 CDS NC_000962 3895654 3898881 1 + 3228 hypothetical protein Rv3479 - none - gi|15610615 fig|83332.1.peg.3483 CDS NC_000962 3900398 3898905 -2 - 1494 hypothetical protein Rv3480c - none - gi|15610616 fig|83332.1.peg.3484 CDS NC_000962 3901178 3900489 -2 - 690 hypothetical protein Rv3481c - none - gi|15610617 fig|83332.1.peg.3485 CDS NC_000962 3902102 3901320 -2 - 783 hypothetical protein Rv3482c - none - gi|15610618 fig|83332.1.peg.3486 CDS NC_000962 3902808 3902146 -3 - 663 Lipoprotein LppP/LprE - none - gi|15610619 fig|83332.1.peg.3487 CDS NC_000962 3903074 3904612 2 + 1539 Cell envelope-associated transcriptional attenuator LytR-CpsA-Psr, subfamily A1 (as in PMID19099556) Cell envelope-associated LytR-CpsA-Psr transcriptional attenuators gi|15610620 fig|83332.1.peg.3488 CDS NC_000962 3905562 3904618 -3 - 945 Oxidoreductase, short-chain dehydrogenase/reductase family - none - gi|15610621 fig|83332.1.peg.3489 CDS NC_000962 3905768 3906217 2 + 450 DoxX family protein - none - gi|15610622 fig|83332.1.peg.3490 CDS NC_000962 3907003 3906170 -1 - 834 Esterase/lipase - none - gi|15610623 fig|83332.1.peg.3491 CDS NC_000962 3907663 3907986 1 + 324 Transcriptional regulator, PadR family CBSS-1352.1.peg.856 gi|15610624 fig|83332.1.peg.3492 CDS NC_000962 3908068 3908232 1 + 165 hypothetical protein Rv3489 - none - gi|15610625 fig|83332.1.peg.3493 CDS NC_000962 3908232 3909734 3 + 1503 Alpha,alpha-trehalose-phosphate synthase [UDP-forming] (EC 2.4.1.15) Trehalose Biosynthesis gi|15610626 fig|83332.1.peg.3494 CDS NC_000962 3909886 3910464 1 + 579 hypothetical protein Rv3491 - none - gi|15610627 fig|83332.1.peg.3495 CDS NC_000962 3910943 3910461 -2 - 483 MCE-associated transmembrane protein - none - gi|15610628 fig|83332.1.peg.3496 CDS NC_000962 3911671 3910943 -1 - 729 MCE-associated alanine and valine rich protein - none - gi|15610629 fig|83332.1.peg.3497 CDS NC_000962 3913365 3911675 -3 - 1691 MCE-family protein Mce1F Mycobacterium virulence operon MCE involved in cell invasion gi|15610630 fig|83332.1.peg.3498 CDS NC_000962 3914530 3913376 -1 - 1155 MCE-family lipoprotein LprK (MCE-family lipoprotein Mce1e) Mycobacterium virulence operon MCE involved in cell invasion gi|15610631 fig|83332.1.peg.3499 CDS NC_000962 3915882 3914527 -3 - 1356 MCE-family protein Mce1D Mycobacterium virulence operon MCE involved in cell invasion gi|15610632 fig|83332.1.peg.3500 CDS NC_000962 3916952 3915879 -2 - 1074 MCE-family protein Mce1C Mycobacterium virulence operon MCE involved in cell invasion gi|15610633 fig|83332.1.peg.3501 CDS NC_000962 3917994 3916942 -3 - 1053 MCE-family protein Mce1B Mycobacterium virulence operon MCE involved in cell invasion gi|15610634 fig|83332.1.peg.3502 CDS NC_000962 3919196 3917994 -2 - 1203 MCE-family protein Mce1A Mycobacterium virulence operon MCE involved in cell invasion gi|15610635 fig|83332.1.peg.3503 CDS NC_000962 3920058 3919216 -3 - 843 Conserved hypothetical integral membrane protein YrbE1B Mycobacterium virulence operon MCE involved in cell invasion gi|15610636 fig|83332.1.peg.3504 CDS NC_000962 3920857 3920093 -1 - 765 Conserved hypothetical integral membrane protein YrbE1A Mycobacterium virulence operon MCE involved in cell invasion gi|15610637 fig|83332.1.peg.3505 CDS NC_000962 3922036 3921083 -1 - 954 Probable short-chain type dehydrogenase/reductase (EC 1.-.-.-) CBSS-164757.7.peg.5020 gi|15610638 fig|83332.1.peg.3506 CDS NC_000962 3922252 3922061 -1 - 192 Ferredoxin - none - gi|15610639 fig|83332.1.peg.3507 CDS NC_000962 3922467 3923669 3 + 1203 Acyl-CoA dehydrogenase FadE26 - none - gi|15610640 fig|83332.1.peg.3508 CDS NC_000962 3923694 3924815 3 + 1122 Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.8.1) - none - gi|15610641 fig|83332.1.peg.3509 CDS NC_000962 3924886 3926394 1 + 1509 Long-chain fatty-acid-CoA ligase (EC 6.2.1.3), Mycobacterial subgroup FadD17 - none - gi|15610642 fig|83332.1.peg.3510 CDS NC_000962 3926565 3930710 3 + 4146 PE family protein - none - gi|15610643 fig|83332.1.peg.3511 CDS NC_000962 3931001 3936706 2 + 5706 PE-PGRS virulence associated protein - none - gi|15610644 fig|83332.1.peg.3512 CDS NC_000962 3938420 3936873 -2 - 1548 COG0028: Thiamine pyrophosphate-requiring enzymes - none - gi|15610645 fig|83332.1.peg.3513 CDS NC_000962 3939253 3938417 -1 - 837 Amidohydrolase family protein - none - gi|15610646 fig|83332.1.peg.3514 CDS NC_000962 3939613 3941757 1 + 2145 PE family protein - none - gi|15610647 fig|83332.1.peg.3515 CDS NC_000962 3941720 3944959 2 + 3240 PE-PGRS virulence associated protein - none - gi|15610648 fig|83332.1.peg.3516 CDS NC_000962 3945744 3945088 -3 - 657 Long-chain fatty-acid-CoA ligase (EC 6.2.1.3), Mycobacterial subgroup FadD19 - none - gi|15610649 fig|83332.1.peg.3517 CDS NC_000962 3945790 3950259 1 + 4470 PE-PGRS virulence associated protein - none - gi|15610650 fig|83332.1.peg.3518 CDS NC_000962 3952466 3950820 -2 - 1647 Long-chain fatty-acid-CoA ligase (EC 6.2.1.3), Mycobacterial subgroup FadD19 Biotin biosynthesis gi|15610651 fig|83332.1.peg.3519 CDS NC_000962 3952540 3953331 1 + 792 Enoyl-CoA hydratase (EC 4.2.1.17) Acetyl-CoA fermentation to Butyrate;
Butanol Biosynthesis;
Fatty acid metabolism cluster;
Isoleucine degradation;
Polyhydroxybutyrate metabolism;
Valine degradation gi|15610652 fig|83332.1.peg.3520 CDS NC_000962 3953427 3954266 3 + 840 hypothetical protein Rv3517 - none - gi|15610653 fig|83332.1.peg.3521 CDS NC_000962 3955517 3954321 -2 - 1197 Cytochrome P450 142A3 - none - gi|15610654 fig|83332.1.peg.3522 CDS NC_000962 3955546 3956256 1 + 711 Acetoacetate decarboxylase family protein - none - gi|15610655 fig|83332.1.peg.3523 CDS NC_000962 3957364 3956321 -1 - 1044 Coenzyme F420-dependent oxidoreductase Anaerobic respiratory reductases gi|15610656 fig|83332.1.peg.3524 CDS NC_000962 3957517 3958428 1 + 912 hypothetical protein Rv3521 - none - gi|15610657 fig|83332.1.peg.3525 CDS NC_000962 3958444 3959508 1 + 1065 hypothetical protein Rv3522 - none - gi|15610658 fig|83332.1.peg.3526 CDS NC_000962 3959525 3960709 2 + 1185 hypothetical protein Rv3523 - none - gi|15610659 fig|83332.1.peg.3527 CDS NC_000962 3960751 3961782 1 + 1032 hypothetical protein Rv3524 - none - gi|15610660 fig|83332.1.peg.3528 CDS NC_000962 3962320 3961796 -1 - 525 Carbonic anhydrases/acetyltransferases - none - gi|15610661 fig|83332.1.peg.3529 CDS NC_000962 3962435 3963595 2 + 1161 hypothetical protein Rv3526 - none - gi|15610662 fig|83332.1.peg.3530 CDS NC_000962 3963601 3964050 1 + 450 hypothetical protein Rv3527 - none - gi|15610663 fig|83332.1.peg.3531 CDS NC_000962 3965188 3964475 -1 - 714 hypothetical protein Rv3528c - none - gi|15610664 fig|83332.1.peg.3532 CDS NC_000962 3967034 3965880 -2 - 1155 hypothetical protein - none - gi|15610665 fig|83332.1.peg.3533 CDS NC_000962 3967816 3967034 -1 - 783 Oxidoreductase, short-chain dehydrogenase/reductase family - none - gi|15610666 fig|83332.1.peg.3534 CDS NC_000962 3968940 3967813 -3 - 1128 hypothetical protein Rv3531c - none - gi|15610667 fig|83332.1.peg.3535 CDS NC_000962 3969339 3970559 3 + 1221 PPE family protein CBSS-164757.7.peg.5020 gi|15610668 fig|83332.1.peg.3536 CDS NC_000962 3972449 3970701 -2 - 1749 PPE family protein CBSS-164757.7.peg.5020 gi|15610669 fig|83332.1.peg.3537 CDS NC_000962 3973588 3972548 -1 - 1041 4-hydroxy-2-oxovalerate aldolase (EC 4.1.3.39) Biphenyl Degradation gi|15610670 fig|83332.1.peg.3538 CDS NC_000962 3974496 3973585 -3 - 912 Acetaldehyde dehydrogenase, acetylating, (EC 1.2.1.10) in gene cluster for degradation of phenols, cresols, catechol Biphenyl Degradation gi|15610671 fig|83332.1.peg.3539 CDS NC_000962 3975292 3974507 -1 - 786 2-keto-4-pentenoate hydratase (EC 4.2.1.80) Biphenyl Degradation gi|15610672 fig|83332.1.peg.3540 CDS NC_000962 3975365 3977056 2 + 1692 3-ketosteroid-delta-1-dehydrogenase - none - gi|15610673 fig|83332.1.peg.3541 CDS NC_000962 3977058 3977918 3 + 861 Enoyl-CoA hydratase - none - gi|15610674 fig|83332.1.peg.3542 CDS NC_000962 3978055 3979494 1 + 1440 PPE family protein CBSS-164757.7.peg.5020 gi|15610675 fig|83332.1.peg.3543 CDS NC_000962 3980655 3979495 -3 - 1161 Lipid carrier protein IgrF Cholesterol catabolic operon in Mycobacteria gi|15610676 fig|83332.1.peg.3544 CDS NC_000962 3981044 3980655 -2 - 390 Enoyl coenzyme A hydratase IgrE Cholesterol catabolic operon in Mycobacteria gi|15610677 fig|83332.1.peg.3545 CDS NC_000962 3981976 3981041 -1 - 936 Conserved protein IgrD Cholesterol catabolic operon in Mycobacteria gi|15610678 fig|83332.1.peg.3546 CDS NC_000962 3983136 3981973 -3 - 1164 Probable acyl-CoA dehydrogenase FadE29 (EC 1.3.99.-); Acyl-CoA dehydrogenase IgrC CBSS-164757.7.peg.5020;
Cholesterol catabolic operon in Mycobacteria gi|15610679 fig|83332.1.peg.3547 CDS NC_000962 3984140 3983121 -2 - 1020 Probable acyl-CoA dehydrogenase FadE28 (EC 1.3.99.-); Acyl-CoA dehydrogenase IgrB CBSS-164757.7.peg.5020;
Cholesterol catabolic operon in Mycobacteria gi|15610680 fig|83332.1.peg.3548 CDS NC_000962 3985441 3984140 -1 - 1302 Putative cytochrome P450 125 (EC 1.14.-.-); Putative cytochrome P450 IgrA CBSS-164757.7.peg.5020;
Cholesterol catabolic operon in Mycobacteria gi|15610681 fig|83332.1.peg.3549 CDS NC_000962 3985553 3986728 2 + 1176 Probable acetyl-CoA acetyltransferase FadA5 (EC 2.3.1.9) CBSS-164757.7.peg.5020 gi|15610682 fig|83332.1.peg.3550 CDS NC_000962 3986840 3987295 2 + 456 Putative uncharacterized protein BCG_3611 CBSS-164757.7.peg.5020 gi|15610683 fig|83332.1.peg.3551 CDS NC_000962 3988292 3987378 -2 - 915 Putative uncharacterized protein (Hypothetical short-chain type dehydrogenase/reductase) CBSS-164757.7.peg.5020 gi|15610684 fig|83332.1.peg.3552 CDS NC_000962 3989094 3988315 -3 - 780 Probable short-chain type dehydrogenase/reductase (EC 1.-.-.-) CBSS-164757.7.peg.5020 gi|15610685 fig|83332.1.peg.3553 CDS NC_000962 3989149 3989892 1 + 744 Probable enoyl-CoA hydratase EchA20 (EC 4.2.1.17) CBSS-164757.7.peg.5020 gi|15610686 fig|83332.1.peg.3554 CDS NC_000962 3989892 3990770 3 + 879 Putative CoA-transferase subunit alpha Rv3551/MT3655 (EC 2.8.3.-) CBSS-164757.7.peg.5020 gi|15610687 fig|83332.1.peg.3555 CDS NC_000962 3990767 3991519 2 + 753 Putative CoA-transferase subunit beta Rv3552/MT3656 (EC 2.8.3.-) CBSS-164757.7.peg.5020 gi|15610688 fig|83332.1.peg.3556 CDS NC_000962 3991617 3992684 3 + 1068 2-nitropropane dioxygenase (EC 1.13.11.32) CBSS-164757.7.peg.5020 gi|15610689 fig|83332.1.peg.3557 CDS NC_000962 3992681 3994738 2 + 2058 Possible electron transfer protein FdxB (EC 1.-.-.-) CBSS-164757.7.peg.5020 gi|15610690 fig|83332.1.peg.3558 CDS NC_000962 3995695 3994826 -1 - 870 Putative uncharacterized protein BCG_3619c CBSS-164757.7.peg.5020 gi|15610691 fig|83332.1.peg.3559 CDS NC_000962 3996960 3995800 -3 - 1161 Probable acetyl-CoA acetyltransferase FadA6 (EC 2.3.1.9) CBSS-164757.7.peg.5020 gi|15610692 fig|83332.1.peg.3560 CDS NC_000962 3997627 3997025 -1 - 603 Transcriptional factor in putative operon for degradation of branched-chain alkanes, nitroalkanes and may be also cyclic ketones, alkenoic acids CBSS-164757.7.peg.5020 gi|15610693 fig|83332.1.peg.3561 CDS NC_000962 3997976 3999634 2 + 1659 PPE family protein CBSS-164757.7.peg.5020 gi|15610694 fig|83332.1.peg.3562 CDS NC_000962 4000431 3999643 -3 - 789 Short-chain dehydrogenase/reductase SDR - none - gi|15610695 fig|83332.1.peg.3563 CDS NC_000962 4001585 4000428 -2 - 1158 FadE30 - none - gi|15610696 fig|83332.1.peg.3564 CDS NC_000962 4001633 4003156 2 + 1524 Long-chain fatty-acid-CoA ligase (EC 6.2.1.3), Mycobacterial subgroup FadD3 - none - gi|15610697 fig|83332.1.peg.3565 CDS NC_000962 4003157 4004290 2 + 1134 Acyl-CoA dehydrogenase FadE31 - none - gi|15610698 fig|83332.1.peg.3566 CDS NC_000962 4004287 4005246 1 + 960 Acyl-CoA dehydrogenase FadE32 Isoleucine degradation gi|15610699 fig|83332.1.peg.3567 CDS NC_000962 4005243 4006199 3 + 957 Acyl-CoA dehydrogenase FadE33 Isoleucine degradation gi|15610700 fig|83332.1.peg.3568 CDS NC_000962 4006196 4007362 2 + 1167 Valine--pyruvate aminotransferase (EC 2.6.1.66) ## AvtA Branched-Chain Amino Acid Biosynthesis gi|15610701 fig|83332.1.peg.3569 CDS NC_000962 4008179 4007181 -2 - 999 N-hydroxyarylamine O-acetyltransferase (EC 2.3.1.118) - none - gi|15610702 fig|83332.1.peg.3570 CDS NC_000962 4009279 4008716 -1 - 564 Nitrilotriacetate monooxygenase component B (EC 1.14.13.-) - none - gi|15610703 fig|83332.1.peg.3571 CDS NC_000962 4010196 4009294 -3 - 903 2,3-dihydroxybiphenyl 1,2-dioxygenase (EC 1.13.11.39) Aromatic dioxygenase mess;
Biphenyl Degradation;
Dioxygenases (EC 1.13.11.-) gi|15610704 fig|83332.1.peg.3572 CDS NC_000962 4011068 4010193 -2 - 876 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase (EC 3.7.1.-) Biphenyl Degradation gi|15610705 fig|83332.1.peg.3573 CDS NC_000962 4012267 4011083 -1 - 1185 Pigment production hydroxylase - none - gi|15610706 fig|83332.1.peg.3574 CDS NC_000962 4012414 4013490 1 + 1077 Phenylacetate-CoA oxygenase/reductase, PaaK subunit - none - gi|15610707 fig|83332.1.peg.3575 CDS NC_000962 4013508 4014038 3 + 531 hypothetical protein Rv3572 - none - gi|15610708 fig|83332.1.peg.3576 CDS NC_000962 4016209 4014074 -1 - 2136 Acyl-CoA dehydrogenase FadE34 - none - gi|15610709 fig|83332.1.peg.3577 CDS NC_000962 4016481 4017080 3 + 600 Transcriptional regulator kstR (Rv3574), TetR family - none - gi|15610710 fig|83332.1.peg.3578 CDS NC_000962 4018165 4017086 -1 - 1080 Transcriptional regulator, LacI family - none - gi|15610711 fig|83332.1.peg.3579 CDS NC_000962 4018355 4019068 2 + 714 Lipoprotein LppH - none - gi|15610712 fig|83332.1.peg.3580 CDS NC_000962 4019259 4020125 3 + 867 Zn-dependent hydrolases of the beta-lactamase fold - none - gi|15610713 fig|83332.1.peg.3581 CDS NC_000962 4020139 4021380 1 + 1242 Arsenic efflux pump protein Arsenic resistance gi|15610714 fig|83332.1.peg.3582 CDS NC_000962 4022390 4021422 -2 - 969 23S rRNA (guanosine-2'-O-) -methyltransferase rlmB (EC 2.1.1.-) ## LSU rRNA Gm2251 RNA methylation gi|15610715 fig|83332.1.peg.3583 CDS NC_000962 4023800 4022391 -2 - 1410 Cysteinyl-tRNA synthetase (EC 6.1.1.16) tRNA aminoacylation, Cys gi|15610716 fig|83332.1.peg.3584 CDS NC_000962 4024344 4023865 -3 - 480 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (EC 4.6.1.12) Isoprenoid Biosynthesis;
Nonmevalonate Branch of Isoprenoid Biosynthesis;
Stationary phase repair cluster gi|15610717 fig|83332.1.peg.3585 CDS NC_000962 4025036 4024341 -2 - 696 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (EC 2.7.7.60) Isoprenoid Biosynthesis;
Nonmevalonate Branch of Isoprenoid Biosynthesis;
Stationary phase repair cluster gi|15610718 fig|83332.1.peg.3586 CDS NC_000962 4025541 4025053 -3 - 489 CarD-like transcriptional regulator - none - gi|15610719 fig|83332.1.peg.3587 CDS NC_000962 4025827 4026375 1 + 549 Lipoprotein LpqE - none - gi|15610720 fig|83332.1.peg.3588 CDS NC_000962 4026441 4027883 3 + 1443 DNA repair protein RadA A DNA integrity scanning protein that co-occurs with RadA;
DNA repair, bacterial;
Proteolysis in bacteria, ATP-dependent gi|15610721 fig|83332.1.peg.3589 CDS NC_000962 4027888 4028964 1 + 1077 DNA integrity scanning protein disA A DNA integrity scanning protein that co-occurs with RadA gi|15610722 fig|83332.1.peg.3590 CDS NC_000962 4029759 4028965 -3 - 795 FIG00820636: hypothetical protein - none - gi|15610723 fig|83332.1.peg.3591 CDS NC_000962 4030491 4029868 -3 - 624 Carbonic anhydrase (EC 4.2.1.1) - none - gi|15610724 fig|83332.1.peg.3592 CDS NC_000962 4030490 4031404 2 + 915 A/G-specific adenine glycosylase (EC 3.2.2.-) DNA repair, bacterial gi|15610725 fig|83332.1.peg.3593 CDS NC_000962 4033155 4031401 -3 - 1755 PE-PGRS virulence associated protein - none - gi|15610726 fig|83332.1.peg.3594 CDS NC_000962 4034039 4033266 -2 - 774 Hydrolase, alpha/beta fold family - none - gi|15610727 fig|83332.1.peg.3595 CDS NC_000962 4034054 4034371 2 + 318 Antibiotic biosynthesis monooxygenase - none - gi|15610728 fig|83332.1.peg.3596 CDS NC_000962 4034349 4035707 3 + 1359 Beta-lactamase (EC 3.5.2.6) - none - gi|15610729 fig|83332.1.peg.3597 CDS NC_000962 4035854 4036681 2 + 828 Phage endolysin - none - gi|15610730 fig|83332.1.peg.3598 CDS NC_000962 4038047 4036728 -2 - 1320 PE family protein - none - gi|15610731 fig|83332.1.peg.3599 CDS NC_000962 4040701 4038155 -1 - 2547 ATP-dependent Clp protease, ATP-binding subunit ClpC / Negative regulator of genetic competence clcC/mecB Proteolysis in bacteria, ATP-dependent gi|15610732 fig|83332.1.peg.3600 CDS NC_000962 4041316 4040978 -1 - 339 Histone protein Lsr2 - none - gi|15610733 fig|83332.1.peg.3601 CDS NC_000962 4042937 4041420 -2 - 1518 Lysyl-tRNA synthetase (class II) (EC 6.1.1.6) tRNA aminoacylation, Lys gi|15610734 fig|83332.1.peg.3602 CDS NC_000962 4043032 4042949 -1 - 84 hypothetical protein Rv3599c - none - gi|15610735 fig|83332.1.peg.3603 CDS NC_000962 4043856 4043038 -3 - 819 Pantothenate kinase type III, CoaX-like (EC 2.7.1.33) Coenzyme A Biosynthesis;
Coenzyme A Biosynthesis cluster gi|15610736 fig|83332.1.peg.3604 CDS NC_000962 4044278 4043859 -2 - 420 Aspartate 1-decarboxylase (EC 4.1.1.11) Coenzyme A Biosynthesis;
Coenzyme A Biosynthesis cluster;
Folate biosynthesis cluster gi|15610737 fig|83332.1.peg.3605 CDS NC_000962 4045207 4044278 -1 - 930 Pantoate--beta-alanine ligase (EC 6.3.2.1) Coenzyme A Biosynthesis;
Coenzyme A Biosynthesis cluster;
Folate biosynthesis cluster gi|15610738 fig|83332.1.peg.3606 CDS NC_000962 4046115 4045204 -3 - 912 Ketopantoate reductase PanG (EC 1.1.1.169) Coenzyme A Biosynthesis cluster;
Folate biosynthesis cluster gi|15610739 fig|83332.1.peg.3607 CDS NC_000962 4047688 4046300 -1 - 1389 Possible membrane protein - none - gi|15610740 fig|83332.1.peg.3608 CDS NC_000962 4048178 4047702 -2 - 477 FIG027937: secreted protein Folate biosynthesis cluster gi|15610741 fig|83332.1.peg.3609 CDS NC_000962 4048744 4048178 -1 - 567 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) Folate Biosynthesis;
Folate biosynthesis cluster gi|15610742 fig|83332.1.peg.3610 CDS NC_000962 4049142 4048741 -3 - 402 Dihydroneopterin aldolase (EC 4.1.2.25) Folate Biosynthesis;
Folate biosynthesis cluster gi|15610743 fig|83332.1.peg.3611 CDS NC_000962 4049977 4049135 -1 - 843 Dihydropteroate synthase (EC 2.5.1.15) Folate Biosynthesis;
Folate biosynthesis cluster gi|15610744 fig|83332.1.peg.3612 CDS NC_000962 4050582 4049974 -3 - 609 GTP cyclohydrolase I (EC 3.5.4.16) type 1 Folate Biosynthesis;
Folate biosynthesis cluster;
Molybdenum cofactor biosynthesis;
Pterin biosynthesis;
tRNA modification Bacteria gi|15610745 fig|83332.1.peg.3613 CDS NC_000962 4052880 4050598 -3 - 2283 Cell division protein FtsH (EC 3.4.24.-) Bacterial Cell Division;
Cell division-ribosomal stress proteins cluster;
Folate biosynthesis cluster gi|15610746 fig|83332.1.peg.3615 CDS NC_000962 4053844 4053515 -1 - 330 FIG116387: hypothetical protein Mycobacterium virulence operon involved in an Esx-1 secretion system gi|15610748 fig|83332.1.peg.3616 CDS NC_000962 4054039 4053878 -1 - 162 ESX-1 secretion system protein (Rv3613c) Mycobacterium virulence operon involved in an Esx-1 secretion system gi|15610749 fig|83332.1.peg.3617 CDS NC_000962 4054693 4054139 -1 - 555 ESX-1 secretion system protein (Rv3614c) Mycobacterium virulence operon involved in an Esx-1 secretion system gi|15610750 fig|83332.1.peg.3618 CDS NC_000962 4055120 4054809 -2 - 312 Highly immunodominant RD1 (Region of Difference 1)-dependent secreted antigen specific for Mycobacterium tuberculosis infection Mycobacterium virulence operon involved in an Esx-1 secretion system gi|15610751 fig|83332.1.peg.3619 CDS NC_000962 4056372 4055194 -3 - 1179 ESX-1 secretion system protein (Rv3616c) Mycobacterium virulence operon involved in an Esx-1 secretion system gi|15610752 fig|83332.1.peg.3620 CDS NC_000962 4057730 4058698 2 + 969 Epoxide hydrolase (EC 3.3.2.9) - none - gi|15610753 fig|83332.1.peg.3621 CDS NC_000962 4058695 4059882 1 + 1188 Limonene 1,2-monooxygenase - none - gi|15610754 fig|83332.1.peg.3622 CDS NC_000962 4060265 4059981 -2 - 285 ESAT-6-like protein EsxL Mycobacterium virulence operon with Esat6-like proteins;
Mycobacterium virulence operon with PE family and Esat6-like proteins gi|15610755 fig|83332.1.peg.3623 CDS NC_000962 4060588 4060292 -1 - 297 ESAT-6-like protein EsxK Mycobacterium virulence operon with Esat6-like proteins;
Mycobacterium virulence operon with PE family and Esat6-like proteins gi|15610756 fig|83332.1.peg.3624 CDS NC_000962 4061886 4060645 -3 - 1242 PPE family protein CBSS-164757.7.peg.5020;
Mycobacterium virulence operon with PE family and Esat6-like proteins gi|15610757 fig|83332.1.peg.3625 CDS NC_000962 4062195 4061896 -3 - 300 PE family protein Mycobacterium virulence operon with PE family and Esat6-like proteins gi|15610758 fig|83332.1.peg.3626 CDS NC_000962 4062524 4063246 2 + 723 Lipoprotein LpqG - none - gi|15610759 fig|83332.1.peg.3627 CDS NC_000962 4063901 4063251 -2 - 651 Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8) Cell division-ribosomal stress proteins cluster;
Folate biosynthesis cluster;
Purine conversions gi|15610760 fig|83332.1.peg.3628 CDS NC_000962 4064869 4063898 -1 - 972 tRNA(Ile)-lysidine synthetase (EC 6.3.4.19) Cell division-ribosomal stress proteins cluster;
Folate biosynthesis cluster;
tRNA modification Bacteria;
tRNA processing gi|15610761 fig|83332.1.peg.3629 CDS NC_000962 4065900 4064848 -3 - 1053 FIG021250: hypothetical protein - none - gi|15610762 fig|83332.1.peg.3630 CDS NC_000962 4067282 4065897 -2 - 1386 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) CBSS-84588.1.peg.1247;
Metallocarboxypeptidases (EC 3.4.17.-);
Murein Hydrolases;
Peptidoglycan Biosynthesis gi|15610763 fig|83332.1.peg.3631 CDS NC_000962 4067420 4067908 2 + 489 Inorganic pyrophosphatase (EC 3.6.1.1) Phosphate metabolism gi|15610764 fig|83332.1.peg.3632 CDS NC_000962 4069051 4067954 -1 - 1098 Possible membrane protein - none - gi|15610765 fig|83332.1.peg.3633 CDS NC_000962 4069172 4070467 2 + 1296 Possible membrane protein - none - gi|15610766 fig|83332.1.peg.3634 CDS NC_000962 4070511 4071236 3 + 726 Glycosyl transferase - none - gi|15610767 fig|83332.1.peg.3635 CDS NC_000962 4071233 4071577 2 + 345 Possible membrane protein - none - gi|15610768 fig|83332.1.peg.3636 CDS NC_000962 4071788 4072663 2 + 876 Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin - none - gi|15610769 fig|83332.1.peg.3637 CDS NC_000962 4073608 4072664 -1 - 945 UDP-glucose 4-epimerase (EC 5.1.3.2) Lactose and Galactose Uptake and Utilization;
Rhamnose containing glycans gi|15610770 fig|83332.1.peg.3638 CDS NC_000962 4073631 4075406 3 + 1776 hypothetical protein Rv3635 - none - gi|15610771 fig|83332.1.peg.3639 CDS NC_000962 4075749 4076096 3 + 348 hypothetical protein Rv3636 - none - gi|15610772 fig|83332.1.peg.3640 CDS NC_000962 4076481 4076981 3 + 501 hypothetical protein Rv3637 - none - gi|15610773 fig|83332.1.peg.3641 CDS NC_000962 4076981 4077727 2 + 747 hypothetical protein Rv3638 - none - gi|15610774 fig|83332.1.peg.3642 CDS NC_000962 4078447 4077881 -1 - 567 hypothetical protein Rv3639c - none - gi|15610775 fig|83332.1.peg.3643 CDS NC_000962 4079746 4078517 -1 - 1230 hypothetical protein Rv3640c - none - gi|15610776 fig|83332.1.peg.3644 CDS NC_000962 4080557 4079922 -2 - 636 (MTCY15C10.11), fic, len: 211. Function: unknown but resembles E. coli Fic Protein that causes cell filamentation and may be involved in cell division. FASTA best: P20605 FIC_ECOLI (200 aa) opt: 323 z-score: 413.9 E():1.8e-16; (31.0%identity in 187 aa overlap) - none - gi|15610777 fig|83332.1.peg.3645 CDS NC_000962 4080762 4080568 -3 - 195 hypothetical protein Rv3642c - none - gi|15610778 fig|83332.1.peg.3646 CDS NC_000962 4081157 4081348 2 + 192 hypothetical protein Rv3643 - none - gi|15610779 fig|83332.1.peg.3647 CDS NC_000962 4082718 4081513 -3 - 1206 DNA polymerase III delta prime subunit (EC 2.7.7.7) Heat shock dnaK gene cluster extended gi|15610780 fig|83332.1.peg.3648 CDS NC_000962 4082804 4084453 2 + 1650 Adenylate cyclase (EC 4.6.1.1) cAMP signaling in bacteria gi|15610781 fig|83332.1.peg.3649 CDS NC_000962 4087254 4084450 -3 - 2805 DNA topoisomerase I (EC 5.99.1.2) Conserved gene cluster associated with Met-tRNA formyltransferase;
DNA topoisomerases, Type I, ATP-independent;
Inteins gi|15610782 fig|83332.1.peg.3650 CDS NC_000962 4088185 4087607 -1 - 579 hypothetical protein Rv3647c - none - gi|15610783 fig|83332.1.peg.3651 CDS NC_000962 4088528 4088325 -2 - 204 Cold shock protein CspA Cold shock, CspA family of proteins gi|15610784 fig|83332.1.peg.3652 CDS NC_000962 4088778 4091093 3 + 2316 ATP-dependent rna helicase, dead/deah box family protein - none - gi|15610785 fig|83332.1.peg.3653 CDS NC_000962 4091230 4091514 1 + 285 PE family protein - none - gi|15610786 fig|83332.1.peg.3654 CDS NC_000962 4091838 4092875 3 + 1038 hypothetical protein - none - gi|15610787 fig|83332.1.peg.3655 CDS NC_000962 4093629 4093787 3 + 159 (MTV025.001A), len: 54. Member of the PGRS(PE) glycine-rich protein family of M. tuberculosis, similarto many e.g. Y03A_MYCTU Q10637 hypothetical glycine-rich49.6 kd pro (603 aa), Fasta scores; opt: 239, E(): 1.8e-15, 77.4% identityin 53 aa overlap. Note that this ORF appears tocontinue inthe the subsequent ORF, but frameshifted at974.No error in the sequence could be found to account for this. - none - gi|15610788 fig|83332.1.peg.3656 CDS NC_000962 4093787 4094524 2 + 738 PE family protein - none - gi|15610789 fig|83332.1.peg.3657 CDS NC_000962 4094911 4094657 -1 - 255 hypothetical protein Rv3654c - none - gi|15610790 fig|83332.1.peg.3658 CDS NC_000962 4095297 4094920 -3 - 378 FIG00822586: hypothetical protein - none - gi|15610791 fig|83332.1.peg.3659 CDS NC_000962 4095527 4095321 -2 - 207 FIG043778: hypothetical protein CBSS-336982.3.peg.3874 gi|15610792 fig|83332.1.peg.3660 CDS NC_000962 4096112 4095537 -2 - 576 FIG054221: Possible conserved alanine rich membrane protein CBSS-336982.3.peg.3874 gi|15610793 fig|83332.1.peg.3661 CDS NC_000962 4096936 4096136 -1 - 801 FIG016317: Probable conserved transmembrane protein CBSS-336982.3.peg.3874 gi|15610794 fig|83332.1.peg.3662 CDS NC_000962 4097991 4096933 -3 - 1059 Flp pilus assembly protein, ATPase CpaF CBSS-336982.3.peg.3874 gi|15610795 fig|83332.1.peg.3663 CDS NC_000962 4099145 4098093 -2 - 1053 Septum site-determining protein MinD @ possible CpaE Bacterial Cell Division;
Bacterial Cytoskeleton;
CBSS-336982.3.peg.3874 gi|15610796 fig|83332.1.peg.3664 CDS NC_000962 4099644 4100507 3 + 864 Phosphoserine phosphatase (EC 3.1.3.3) CBSS-336982.3.peg.3874;
Glycine and Serine Utilization;
Serine Biosynthesis gi|15610797 fig|83332.1.peg.3665 CDS NC_000962 4102032 4101262 -3 - 771 hypothetical protein Rv3662c - none - gi|15610798 fig|83332.1.peg.3666 CDS NC_000962 4103675 4102029 -2 - 1647 Dipeptide transport ATP-binding protein DppD (TC 3.A.1.5.2) ABC transporter dipeptide (TC 3.A.1.5.2) gi|15610799 fig|83332.1.peg.3667 CDS NC_000962 4104472 4103672 -1 - 801 Dipeptide transport system permease protein DppC (TC 3.A.1.5.2) ABC transporter dipeptide (TC 3.A.1.5.2) gi|15610800 fig|83332.1.peg.3668 CDS NC_000962 4105454 4104528 -2 - 927 Dipeptide transport system permease protein DppB (TC 3.A.1.5.2) ABC transporter dipeptide (TC 3.A.1.5.2) gi|15610801 fig|83332.1.peg.3669 CDS NC_000962 4107081 4105456 -3 - 1626 Dipeptide-binding ABC transporter, periplasmic substrate-binding component (TC 3.A.1.5.2) ABC transporter dipeptide (TC 3.A.1.5.2) gi|15610802 fig|83332.1.peg.3670 CDS NC_000962 4107789 4109744 3 + 1956 Acetyl-coenzyme A synthetase (EC 6.2.1.1) Methylcitrate cycle;
Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate gi|15610803 fig|83332.1.peg.3671 CDS NC_000962 4110478 4109780 -1 - 699 Protease - none - gi|15610804 fig|83332.1.peg.3672 CDS NC_000962 4110824 4111342 2 + 519 FIG00820727: hypothetical protein - none - gi|15610805 fig|83332.1.peg.3673 CDS NC_000962 4111343 4112326 2 + 984 (MTV025.018), len: 327, ephE, Probable epoxide hydrolase similar to many, involved in detoxification,aromatic hydrocarbons catabolism. FASTA scores: gp|D85082|D85082_23 Bacillus subtilis DNA, genome sequ (286 aa)opt: 311 z-score: 364.3 E(): 8.9e-13, 29.2% identity in 308 aa overlap. ALSO similar to mycobacterial hypothetical proteins: MTCY9F9_26, MTCY7H7B_5, and others, CEK07C5_6; GMGABCEP_1, HYES_HUMAN, ATAC003105_11; etc. Contains PS00213 Lipocalin signature. - none - gi|15610806 fig|83332.1.peg.3674 CDS NC_000962 4113512 4112319 -2 - 1194 Trypsin-like serine protease with C-terminal PDZ domain - none - gi|15610807 fig|83332.1.peg.3675 CDS NC_000962 4114339 4113518 -1 - 822 Hypothetical nudix hydrolase YeaB Nudix proteins (nucleoside triphosphate hydrolases) gi|15610808 fig|83332.1.peg.3676 CDS NC_000962 4115154 4114471 -3 - 684 Membrane-anchored thioredoxin - none - gi|15610809 fig|83332.1.peg.3677 CDS NC_000962 4115834 4115154 -2 - 681 Endonuclease III (EC 4.2.99.18) DNA Repair Base Excision gi|15610810 fig|83332.1.peg.3678 CDS NC_000962 4115999 4116376 2 + 378 Possible membrane protein - none - gi|15610811 fig|83332.1.peg.3679 CDS NC_000962 4116475 4117149 1 + 675 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Glutathione-regulated potassium-efflux system and associated functions;
cAMP signaling in bacteria gi|15610812 fig|83332.1.peg.3680 CDS NC_000962 4118049 4117255 -3 - 795 FIG146518: Zn-dependent hydrolases, including glyoxylases - none - gi|15610813 fig|83332.1.peg.3681 CDS NC_000962 4118511 4118056 -3 - 456 FIG137598: hypothetical protein - none - gi|15610814 fig|83332.1.peg.3682 CDS NC_000962 4118773 4119795 1 + 1023 Arsenical pump-driving ATPase (EC 3.6.3.16) Arsenic resistance;
Stress related cluster;
cAMP signaling in bacteria gi|15610815 fig|83332.1.peg.3683 CDS NC_000962 4119792 4120952 3 + 1161 Arsenical pump-driving ATPase (EC 3.6.3.16) Arsenic resistance;
Stress related cluster;
cAMP signaling in bacteria gi|15610816 fig|83332.1.peg.3684 CDS NC_000962 4121497 4121195 -1 - 303 WhiB-type transcription regulator WhiB and WhiB-type regulatory proteins gi|15610817 fig|83332.1.peg.3685 CDS NC_000962 4121913 4124345 3 + 2433 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) Peptidoglycan Biosynthesis;
WhiB and WhiB-type regulatory proteins gi|15610818 fig|83332.1.peg.3686 CDS NC_000962 4124414 4125373 2 + 960 Putative phosphohydrolase - none - gi|15610819 fig|83332.1.peg.3687 CDS NC_000962 4125436 4126476 1 + 1041 Cysteine synthase (EC 2.5.1.47) - none - gi|15610820 fig|83332.1.peg.3688 CDS NC_000962 4128722 4127292 -2 - 1431 Probable cytochrome P450 137 cyp137 (EC 1.14.-.-) - none - gi|15610821 fig|83332.1.peg.3689 CDS NC_000962 4129080 4128748 -3 - 333 hypothetical protein Rv3686c - none - gi|15610822 fig|83332.1.peg.3690 CDS NC_000962 4129688 4129320 -2 - 369 Anti-anti-sigma factor RsfB - none - gi|15610823 fig|83332.1.peg.3691 CDS NC_000962 4130354 4129890 -2 - 465 GatB/Yqey domain-containing protein - none - gi|15610824 fig|83332.1.peg.3692 CDS NC_000962 4130354 4131709 2 + 1356 Possible membrane protein - none - gi|15610825 fig|83332.1.peg.3693 CDS NC_000962 4131736 4132389 1 + 654 Possible membrane protein - none - gi|15610826 fig|83332.1.peg.3694 CDS NC_000962 4132515 4133516 3 + 1002 Putative secreted protein - none - gi|15610827 fig|83332.1.peg.3695 CDS NC_000962 4133513 4134589 2 + 1077 MoxR-like ATPase - none - gi|15610828 fig|83332.1.peg.3696 CDS NC_000962 4134723 4136045 3 + 1323 Possible membrane protein - none - gi|15610829 fig|83332.1.peg.3697 CDS NC_000962 4137111 4136119 -3 - 993 Possible membrane protein - none - gi|15610830 fig|83332.1.peg.3698 CDS NC_000962 4137203 4138135 2 + 933 Possible membrane protein - none - gi|15610831 fig|83332.1.peg.3699 CDS NC_000962 4139752 4138199 -1 - 1554 Glycerol kinase (EC 2.7.1.30) Glycerol and Glycerol-3-phosphate Uptake and Utilization;
Glycerolipid and Glycerophospholipid Metabolism in Bacteria gi|15610832 fig|83332.1.peg.3700 CDS NC_000962 4140239 4139802 -2 - 438 Toxin 1, PIN domain Toxin-Antitoxin MT1 gi|15610833 fig|83332.1.peg.3701 CDS NC_000962 4140490 4142019 1 + 1530 hypothetical protein Rv3698 - none - gi|15610834 fig|83332.1.peg.3702 CDS NC_000962 4142041 4142742 1 + 702 Methyltransferase (EC 2.1.1.-) - none - gi|15610835 fig|83332.1.peg.3703 CDS NC_000962 4143917 4142745 -2 - 1173 Aminotransferase, class V - none - gi|15610836 fig|83332.1.peg.3704 CDS NC_000962 4144913 4143948 -2 - 966 Dimethylhistidine N-methyltransferase (EC 2.1.1.44) - none - gi|15610837 fig|83332.1.peg.3705 CDS NC_000962 4145611 4144910 -1 - 702 hypothetical protein Rv3702c - none - gi|15610838 fig|83332.1.peg.3706 CDS NC_000962 4146888 4145611 -3 - 1278 Putative methyltransferase - none - gi|15610839 fig|83332.1.peg.3707 CDS NC_000962 4148183 4146885 -2 - 1299 Similar to Glutamate--cysteine ligase (EC 6.3.2.2), function unknown Glutathione analogs: mycothiol gi|15610840 fig|83332.1.peg.3708 CDS NC_000962 4148959 4148315 -1 - 645 hypothetical protein Rv3705c - none - gi|15610841 fig|83332.1.peg.3709 CDS NC_000962 4149908 4149588 -2 - 321 FIG00820599: hypothetical protein - none - gi|15610842 fig|83332.1.peg.3710 CDS NC_000962 4151037 4150027 -3 - 1011 FIG00821722: hypothetical protein - none - gi|15610843 fig|83332.1.peg.3711 CDS NC_000962 4152214 4151177 -1 - 1038 Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) Lysine Biosynthesis DAP Pathway;
Lysine Biosynthesis DAP Pathway, GJO scratch;
Threonine and Homoserine Biosynthesis gi|15610844 fig|83332.1.peg.3712 CDS NC_000962 4153480 4152215 -1 - 1266 Aspartokinase (EC 2.7.2.4) Lysine Biosynthesis DAP Pathway;
Lysine Biosynthesis DAP Pathway, GJO scratch;
Threonine and Homoserine Biosynthesis gi|15610845 fig|83332.1.peg.3713 CDS NC_000962 4153737 4155671 3 + 1935 2-isopropylmalate synthase (EC 2.3.3.13) Branched-Chain Amino Acid Biosynthesis;
Leucine Biosynthesis gi|15610846 fig|83332.1.peg.3714 CDS NC_000962 4156726 4155737 -1 - 990 DNA polymerase III epsilon subunit DnaQ (EC 2.7.7.7) - none - gi|15610847 fig|83332.1.peg.3715 CDS NC_000962 4156978 4158219 1 + 1242 proposed amino acid ligase found clustered with an amidotransferase - none - gi|15610848 fig|83332.1.peg.3716 CDS NC_000962 4158224 4158919 2 + 696 Putative amidotransferase similar to cobyric acid synthase Cobalamin synthesis gi|15610849 fig|83332.1.peg.3717 CDS NC_000962 4159818 4158928 -3 - 891 hypothetical protein Rv3714c - none - gi|15610850 fig|83332.1.peg.3718 CDS NC_000962 4160497 4159886 -1 - 612 Recombination protein RecR DNA processing cluster;
DNA repair, bacterial RecFOR pathway gi|15610851 fig|83332.1.peg.3719 CDS NC_000962 4160910 4160509 -3 - 402 FIG000557: hypothetical protein co-occurring with RecR DNA processing cluster gi|15610852 fig|83332.1.peg.3720 CDS NC_000962 4161045 4161770 3 + 726 N-acetylmuramoyl-L-alanine amidase - none - gi|15610853 fig|83332.1.peg.3721 CDS NC_000962 4162255 4161812 -1 - 444 hypothetical protein Rv3718c - none - gi|15610854 fig|83332.1.peg.3722 CDS NC_000962 4162303 4163715 1 + 1413 FAD/FMN-containing dehydrogenases - none - gi|15610855 fig|83332.1.peg.3723 CDS NC_000962 4163733 4164995 3 + 1263 Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79) - none - gi|15610856 fig|83332.1.peg.3724 CDS NC_000962 4166728 4164992 -1 - 1737 DNA polymerase III subunits gamma and tau (EC 2.7.7.7) DNA processing cluster gi|15610857 fig|83332.1.peg.3725 CDS NC_000962 4168044 4166818 -3 - 1227 Alanine-glyoxylate amino-transferase - none - gi|15610858 fig|83332.1.peg.3726 CDS NC_000962 4168533 4169297 3 + 765 Possible membrane protein - none - gi|15610859 fig|83332.1.peg.3727 CDS NC_000962 4169603 4170166 2 + 564 Cutinase - none - gi|15610860 fig|83332.1.peg.3728 CDS NC_000962 4170211 4171140 1 + 930 Oxidoreductase - none - gi|15610861 fig|83332.1.peg.3729 CDS NC_000962 4171418 4172611 2 + 1194 2,3-butanediol dehydrogenase, R-alcohol forming, (R)- and (S)-acetoin-specific (EC 1.1.1.4) - none - gi|15610862 fig|83332.1.peg.3730 CDS NC_000962 4172952 4174760 3 + 1809 Possible oxidoreductase - none - gi|15610863 fig|83332.1.peg.3731 CDS NC_000962 4174870 4178067 1 + 3198 EmrB/QacA family drug resistance transporter - none - gi|15610864 fig|83332.1.peg.3732 CDS NC_000962 4178282 4180612 2 + 2331 Possible Fe-S oxidoreductase - none - gi|15610865 fig|83332.1.peg.3733 CDS NC_000962 4181717 4180677 -2 - 1041 ATP-dependent DNA ligase (EC 6.5.1.1) DNA Repair Base Excision;
DNA ligases gi|15610866 fig|83332.1.peg.3734 CDS NC_000962 4181755 4182831 1 + 1077 ATP-dependent DNA ligase (EC 6.5.1.1) LigC DNA Repair Base Excision;
DNA ligases;
Nonhomologous End-Joining in Bacteria gi|15610867 fig|83332.1.peg.3735 CDS NC_000962 4182931 4183989 1 + 1059 hypothetical protein Rv3732 - none - gi|15610868 fig|83332.1.peg.3736 CDS NC_000962 4184509 4184009 -1 - 501 MutT/nudix family protein - none - gi|15610869 fig|83332.1.peg.3737 CDS NC_000962 4185887 4184523 -2 - 1365 Diacyglycerol O-acyltransferase (EC 2.3.1.20) - none - gi|15610870 fig|83332.1.peg.3738 CDS NC_000962 4186086 4186574 3 + 489 Adenosine specific kinase - none - gi|15610871 fig|83332.1.peg.3739 CDS NC_000962 4186631 4187692 2 + 1062 Transcriptional regulator, AraC family - none - gi|15610872 fig|83332.1.peg.3740 CDS NC_000962 4187696 4189285 2 + 1590 hypothetical protein Rv3737 - none - gi|15610873 fig|83332.1.peg.3741 CDS NC_000962 4190229 4189282 -3 - 948 PPE family protein - none - gi|15610874 fig|83332.1.peg.3742 CDS NC_000962 4190514 4190281 -3 - 234 (MTV025.087c), len: 77. Member of the M. tuberculosis PPE family, shows high homology with gp|AL0212|MTV012_32 and MTV012_36 Mycobacterium tuberculosis sequenc(434 aa); FASTA scores: opt: 398 z-score: 494.7 E(): 4.9e-20; 74.0% identity in 77 aa overlap. Also similar to MTCY21B4_4 and other PPE members. ORF ends at stop codon at position 97470,which is not present in similar ORFs: MTV012_32,or MTCY21B4_4. Sequence homology with MTV012_32, and MTCY21B4_4 continues in the downstream ORF MTV025.86c. Sequencewaschecked,but no errors were detected. A similar situation,but withaframeshift separating the ORFs is found in MTV012_36/MTV012_35. ORF MTV025.87c shows similarity also to MTV035_14;MTCY6A4_1; MTV035_8; MTV037_17; MLCB2492_30; MTCY261_19,MTCY251_15; MTCY3A2_23; MTCY28_16 etc. - none - gi|15610875 fig|83332.1.peg.3743 CDS NC_000962 4192176 4190830 -3 - 1347 Diacyglycerol O-acyltransferase (EC 2.3.1.20) - none - gi|15610876 fig|83332.1.peg.3744 CDS NC_000962 4192850 4192176 -2 - 675 Monooxygenase, flavin-binding family - none - gi|15610877 fig|83332.1.peg.3745 CDS NC_000962 4193242 4192847 -1 - 396 Monooxygenase, flavin-binding family - none - gi|15610878 fig|83332.1.peg.3746 CDS NC_000962 4195370 4193388 -2 - 1983 Cobalt(II) exporting P1-type ATPase - none - gi|15610879 fig|83332.1.peg.3747 CDS NC_000962 4195437 4195799 3 + 363 Cobalt(II) binding transcription repressor, nmtR - none - gi|15610880 fig|83332.1.peg.3748 CDS NC_000962 4196095 4195883 -1 - 213 hypothetical protein Rv3745c - none - gi|15610881 fig|83332.1.peg.3749 CDS NC_000962 4196503 4196168 -1 - 336 PE family protein - none - gi|15610882 fig|83332.1.peg.3750 CDS NC_000962 4196721 4197104 3 + 384 hypothetical protein - none - gi|15610883 fig|83332.1.peg.3751 CDS NC_000962 4197233 4197592 2 + 360 hypothetical protein Rv3748 - none - gi|15610884 fig|83332.1.peg.3752 CDS NC_000962 4198134 4197625 -3 - 510 hypothetical protein Rv3749c - none - gi|15610885 fig|83332.1.peg.3753 CDS NC_000962 4198594 4198202 -1 - 393 Excisionase - none - gi|15610886 fig|83332.1.peg.3754 CDS NC_000962 4198871 4199086 2 + 216 Integrase - none - gi|15610887 fig|83332.1.peg.3755 CDS NC_000962 4199702 4199244 -2 - 459 tRNA-specific adenosine-34 deaminase (EC 3.5.4.-) tRNA modification Bacteria;
tRNA processing gi|15610888 fig|83332.1.peg.3756 CDS NC_000962 4200218 4199718 -2 - 501 hypothetical protein Rv3753c - none - gi|15610889 fig|83332.1.peg.3757 CDS NC_000962 4200418 4201323 1 + 906 Arogenate dehydrogenase (EC 1.3.1.43) # TyrAa, NAD(P)-specific, incomplete N-terminus Chorismate Synthesis;
Phenylalanine and Tyrosine Branches from Chorismate;
Ribosome post-transcriptional modification and chromosomal segregation cluster gi|15610890 fig|83332.1.peg.3758 CDS NC_000962 4201885 4201286 -1 - 600 hypothetical protein Rv3755c - none - gi|15610891 fig|83332.1.peg.3759 CDS NC_000962 4202610 4201891 -3 - 720 Glycine betaine ABC transport system permease protein Choline and Betaine Uptake and Betaine Biosynthesis gi|15610892 fig|83332.1.peg.3760 CDS NC_000962 4203296 4202607 -2 - 690 L-proline glycine betaine ABC transport system permease protein ProW (TC 3.A.1.12.1) Choline and Betaine Uptake and Betaine Biosynthesis gi|15610893 fig|83332.1.peg.3761 CDS NC_000962 4204414 4203284 -1 - 1131 L-proline glycine betaine ABC transport system permease protein ProV (TC 3.A.1.12.1) Choline and Betaine Uptake and Betaine Biosynthesis gi|15610894 fig|83332.1.peg.3762 CDS NC_000962 4205370 4204423 -3 - 948 L-proline glycine betaine binding ABC transporter protein ProX (TC 3.A.1.12.1) - none - gi|15610895 fig|83332.1.peg.3763 CDS NC_000962 4205535 4205837 3 + 303 Possible membrane protein - none - gi|15610896 fig|83332.1.peg.3764 CDS NC_000962 4206914 4205859 -2 - 1056 Acyl-CoA dehydrogenase FadE36 (EC 1.3.99.-) - none - gi|15610897 fig|83332.1.peg.3765 CDS NC_000962 4208873 4206993 -2 - 1881 Alkyl sulfatase (EC 3.1.6.-) - none - gi|15610898 fig|83332.1.peg.3766 CDS NC_000962 4209044 4209523 2 + 480 19 kDa lipoprotein antigen precursor LpqH - none - gi|15610899 fig|83332.1.peg.3767 CDS NC_000962 4211006 4209579 -2 - 1428 Two component system sensor histidine kinase - none - gi|15610900 fig|83332.1.peg.3768 CDS NC_000962 4211781 4211077 -3 - 705 Two component system transcriptional regulator - none - gi|15610901 fig|83332.1.peg.3769 CDS NC_000962 4212290 4212979 2 + 690 hypothetical protein Rv3766 - none - gi|15610902 fig|83332.1.peg.3770 CDS NC_000962 4213937 4212993 -2 - 945 O-Methyltransferase involved in polyketide biosynthesis - none - gi|15610903 fig|83332.1.peg.3771 CDS NC_000962 4214067 4214426 3 + 360 hypothetical protein Rv3768 - none - gi|15610904 fig|83332.1.peg.3772 CDS NC_000962 4214612 4214884 2 + 273 hypothetical protein Rv3769 - none - gi|15610905 fig|83332.1.peg.3773 CDS NC_000962 4215772 4215197 -1 - 576 FIG00820132: hypothetical protein - none - gi|15610906 fig|83332.1.peg.3774 CDS NC_000962 4216727 4216401 -2 - 327 hypothetical protein Rv3771c - none - gi|15610907 fig|83332.1.peg.3775 CDS NC_000962 4217131 4218192 1 + 1062 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) Phenylalanine and Tyrosine Branches from Chorismate gi|15610908 fig|83332.1.peg.3776 CDS NC_000962 4218822 4218238 -3 - 585 Transcriptional regulator, ArsR family - none - gi|15610909 fig|83332.1.peg.3777 CDS NC_000962 4218846 4219670 3 + 825 Enoyl-CoA hydratase - none - gi|15610910 fig|83332.1.peg.3778 CDS NC_000962 4219682 4220929 2 + 1248 Beta-lactamase - none - gi|15610911 fig|83332.1.peg.3779 CDS NC_000962 4221086 4222645 2 + 1560 13E12 repeat family protein - none - gi|15610912 fig|83332.1.peg.3780 CDS NC_000962 4222691 4223677 2 + 987 Quinone oxidoreductase (EC 1.6.5.5) - none - gi|15610913 fig|83332.1.peg.3781 CDS NC_000962 4224892 4223696 -1 - 1197 Cysteine desulfurase (EC 2.8.1.7) Alanine biosynthesis;
CBSS-84588.1.peg.1247;
RNA methylation;
mnm5U34 biosynthesis bacteria;
tRNA modification Bacteria gi|15610914 fig|83332.1.peg.3782 CDS NC_000962 4224982 4226982 1 + 2001 FIG00820726: hypothetical protein - none - gi|15610915 fig|83332.1.peg.3783 CDS NC_000962 4226986 4227522 1 + 537 hypothetical protein Rv3780 - none - gi|15610916 fig|83332.1.peg.3784 CDS NC_000962 4227526 4228347 1 + 822 ABC O-antigen transporter, ATP-binding component - none - gi|15610917 fig|83332.1.peg.3785 CDS NC_000962 4228344 4229258 3 + 915 Glycosyl transferase, family 2 - none - gi|15610918 fig|83332.1.peg.3786 CDS NC_000962 4229255 4230097 2 + 843 O-antigen export system permease protein RfbD Rhamnose containing glycans gi|15610919 fig|83332.1.peg.3787 CDS NC_000962 4230253 4231233 1 + 981 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) # frameshift Rhamnose containing glycans;
dTDP-rhamnose synthesis gi|15610920 fig|83332.1.peg.3788 CDS NC_000962 4231317 4232390 3 + 1074 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) - none - gi|15610921 fig|83332.1.peg.3789 CDS NC_000962 4233594 4232371 -3 - 1224 hypothetical protein Rv3786c - none - gi|15610922 fig|83332.1.peg.3790 CDS NC_000962 4234533 4233607 -3 - 927 Putative S-adenosyl-L-methionine-dependent methyltransferase - none - gi|15610923 fig|83332.1.peg.3791 CDS NC_000962 4234777 4235262 1 + 486 Nucleoside diphosphate kinase regulator - none - gi|15610924 fig|83332.1.peg.3792 CDS NC_000962 4235371 4235736 1 + 366 Possible membrane protein - none - gi|15610925 fig|83332.1.peg.3793 CDS NC_000962 4235776 4237161 1 + 1386 Oxidoreductase, FAD-binding protein - none - gi|15610926 fig|83332.1.peg.3794 CDS NC_000962 4237162 4237926 1 + 765 Oxidoreductase, short-chain dehydrogenase/reductase family - none - gi|15610927 fig|83332.1.peg.3795 CDS NC_000962 4237929 4239860 3 + 1932 Arabinofuranosyltransferase AftA - none - gi|15610928 fig|83332.1.peg.3796 CDS NC_000962 4239860 4243144 2 + 3285 INTEGRAL MEMBRANE INDOLYLACETYLINOSITOL ARABINOSYLTRANSFERASE EMBC (ARABINOSYLINDOLYLACETYLINOSITOL SYNTHASE) - none - gi|15610929 fig|83332.1.peg.3797 CDS NC_000962 4243230 4246514 3 + 3285 Probable arabinosyltransferase A (EC 2.4.2.-) - none - gi|15610930 fig|83332.1.peg.3798 CDS NC_000962 4246511 4249807 2 + 3297 Probable arabinosyltransferase B (EC 2.4.2.-) - none - gi|15610931 fig|83332.1.peg.3799 CDS NC_000962 4249875 4251002 3 + 1128 Putative uncharacterized protein BCG_3858 - none - gi|15610932 fig|83332.1.peg.3800 CDS NC_000962 4251082 4252863 1 + 1782 Probable acyl-CoA dehydrogenase fadE35 (EC 1.3.99.-) CBSS-83332.1.peg.3803 gi|15610933 fig|83332.1.peg.3801 CDS NC_000962 4252990 4254324 1 + 1335 Mobile element protein CBSS-83332.1.peg.3803 gi|15610934 fig|83332.1.peg.3802 CDS NC_000962 4255945 4254395 -1 - 1551 Propionyl-CoA carboxylase beta chain (EC 6.4.1.3) CBSS-83332.1.peg.3803;
Mycobacterium virulence operon involved in fatty acids biosynthesis;
Serine-glyoxylate cycle gi|15610935 fig|83332.1.peg.3803 CDS NC_000962 4261143 4255942 -3 - 5202 Probable polyketide synthase, similar to many. e.g. gp|M63676|SERERYAA_1 S.erythraea first ORF of eryA gene, involved in complex polyketide formation in erythromycin biosynthesis. CBSS-83332.1.peg.3803 gi|15610936 fig|83332.1.peg.3804 CDS NC_000962 4263063 4261150 -3 - 1914 Long-chain fatty-acid-AMP ligase, Mycobacterial subgroup FadD32 CBSS-83332.1.peg.3803 gi|15610937 fig|83332.1.peg.3805 CDS NC_000962 4264362 4263352 -3 - 1011 hypothetical protein Rv3802c CBSS-83332.1.peg.3803 gi|15610938 fig|83332.1.peg.3806 CDS NC_000962 4265459 4264560 -2 - 900 Antigen 85-C precursor (85C) (Antigen 85 complex C) (Ag85C) (Mycolyl transferase 85C) (EC 2.3.1.-) CBSS-83332.1.peg.3803 gi|15610939 fig|83332.1.peg.3807 CDS NC_000962 4266655 4265639 -1 - 1017 Antigen 85-A precursor (85A) (Antigen 85 complex A) (Ag85A) (Mycolyl transferase 85A) (EC 2.3.1.-) CBSS-83332.1.peg.3803 gi|15610940 fig|83332.1.peg.3808 CDS NC_000962 4268833 4266950 -1 - 1884 hypothetical protein Rv3805c CBSS-83332.1.peg.3803 gi|15610941 fig|83332.1.peg.3809 CDS NC_000962 4269830 4268922 -2 - 909 Phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase - none - gi|15610942 fig|83332.1.peg.3810 CDS NC_000962 4270334 4269837 -2 - 498 FIG008913: Membrane-associated phospholipid phosphatase - none - gi|15610943 fig|83332.1.peg.3811 CDS NC_000962 4272276 4270363 -3 - 1914 Galactofuranosyl transferase (EC 2.-.-.-) - none - gi|15610944 fig|83332.1.peg.3812 CDS NC_000962 4273472 4272273 -2 - 1200 UDP-galactopyranose mutase (EC 5.4.99.9) - none - gi|15610945 fig|83332.1.peg.3813 CDS NC_000962 4273736 4274590 2 + 855 Exported repetitive protein precursor (Cell surface protein pirG) (EXP53) - none - gi|15610946 fig|83332.1.peg.3814 CDS NC_000962 4274795 4276414 2 + 1620 Putative uncharacterized protein BCG_3873 - none - gi|15610947 fig|83332.1.peg.3815 CDS NC_000962 4276568 4278082 2 + 1515 PE-PGRS FAMILY PROTEIN - none - gi|15610948 fig|83332.1.peg.3816 CDS NC_000962 4279212 4278391 -3 - 822 Cof family hydrolase - none - gi|15610949 fig|83332.1.peg.3817 CDS NC_000962 4280012 4279227 -2 - 786 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51) Glycerolipid and Glycerophospholipid Metabolism in Bacteria gi|15610950 fig|83332.1.peg.3818 CDS NC_000962 4280785 4280030 -1 - 756 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51) Glycerolipid and Glycerophospholipid Metabolism in Bacteria;
Phosphate metabolism;
Ribosome post-transcriptional modification and chromosomal segregation cluster gi|15610951 fig|83332.1.peg.3819 CDS NC_000962 4281568 4280789 -1 - 780 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51) Glycerolipid and Glycerophospholipid Metabolism in Bacteria;
Phosphate metabolism;
Ribosome post-transcriptional modification and chromosomal segregation cluster gi|15610952 fig|83332.1.peg.3820 CDS NC_000962 4281644 4282399 2 + 756 aminoglycoside 3'-phosphotransferase - none - gi|15610953 fig|83332.1.peg.3821 CDS NC_000962 4282446 4283996 3 + 1551 Rieske (2Fe-2S) domain protein - none - gi|15610954 fig|83332.1.peg.3822 CDS NC_000962 4283993 4284328 2 + 336 Putative uncharacterized protein BCG_3881 - none - gi|15610955 fig|83332.1.peg.3823 CDS NC_000962 4285822 4284416 -1 - 1407 Polyketide synthase associated protein papA2 - none - gi|15610956 fig|83332.1.peg.3824 CDS NC_000962 4285970 4286683 2 + 714 hypothetical protein Rv3821 - none - gi|15610957 fig|83332.1.peg.3825 CDS NC_000962 4286718 4287932 3 + 1215 PE family protein - none - gi|15610958 fig|83332.1.peg.3826 CDS NC_000962 4291526 4288257 -2 - 3270 Integral membrane transport protein MmpL8 - none - gi|15610959 fig|83332.1.peg.3827 CDS NC_000962 4293171 4291636 -3 - 1536 Polyketide synthase associated protein PapA1 - none - gi|15610960 fig|83332.1.peg.3828 CDS NC_000962 4299602 4293222 -2 - 6381 Polyketide synthase Pks2 - none - gi|15610961 fig|83332.1.peg.3829 CDS NC_000962 4299809 4301563 2 + 1755 Long-chain fatty-acid-AMP ligase, Mycobacterial subgroup FadD23 Biotin biosynthesis gi|15610962 fig|83332.1.peg.3830 CDS NC_000962 4302786 4301560 -3 - 1227 Mobile element protein - none - gi|15610963 fig|83332.1.peg.3831 CDS NC_000962 4303394 4302783 -2 - 612 Resolvase - none - gi|15610964 fig|83332.1.peg.3832 CDS NC_000962 4305005 4303395 -2 - 1611 Dehydrogenase - none - gi|15610965 fig|83332.1.peg.3833 CDS NC_000962 4305682 4305053 -1 - 630 Transcriptional regulator, TetR family - none - gi|15610966 fig|83332.1.peg.3834 CDS NC_000962 4305754 4306236 1 + 483 hypothetical protein Rv3831 - none - gi|15610967 fig|83332.1.peg.3835 CDS NC_000962 4306808 4306233 -2 - 576 hypothetical protein Rv3832c - none - gi|15610968 fig|83332.1.peg.3836 CDS NC_000962 4306864 4307655 1 + 792 Transcriptional regulator, AraC family - none - gi|15610969 fig|83332.1.peg.3837 CDS NC_000962 4308911 4307652 -2 - 1260 Seryl-tRNA synthetase (EC 6.1.1.11) Glycine and Serine Utilization;
tRNA aminoacylation, Ser gi|15610970 fig|83332.1.peg.3838 CDS NC_000962 4309044 4310393 3 + 1350 Possible membrane protein - none - gi|15610971 fig|83332.1.peg.3839 CDS NC_000962 4310398 4310811 1 + 414 hypothetical protein Rv3836 - none - gi|15610972 fig|83332.1.peg.3840 CDS NC_000962 4311704 4311006 -2 - 699 putative phosphoglycerate mutase - none - gi|15610973 fig|83332.1.peg.3841 CDS NC_000962 4312666 4311701 -1 - 966 Prephenate dehydratase (EC 4.2.1.51) # PheAIp/ACT domain Cell envelope-associated LytR-CpsA-Psr transcriptional attenuators;
Chorismate Synthesis;
Phenylalanine and Tyrosine Branches from Chorismate gi|15610974 fig|83332.1.peg.3842 CDS NC_000962 4312762 4313538 1 + 777 hypothetical protein Rv3839 - none - gi|15610975 fig|83332.1.peg.3843 CDS NC_000962 4313564 4313977 2 + 414 Cell envelope-associated transcriptional attenuator LytR-CpsA-Psr, subfamily A1 (as in PMID19099556) - none - gi|15610976 fig|83332.1.peg.3844 CDS NC_000962 4314175 4314720 1 + 546 Ferritin - none - gi|15610977 fig|83332.1.peg.3845 CDS NC_000962 4315559 4314735 -2 - 825 Glycerophosphoryl diester phosphodiesterase (EC 3.1.4.46) Glycerol and Glycerol-3-phosphate Uptake and Utilization gi|15610978 fig|83332.1.peg.3846 CDS NC_000962 4316593 4315565 -1 - 1029 Possible membrane protein - none - gi|15610979 fig|83332.1.peg.3847 CDS NC_000962 4318772 4319263 2 + 492 Mobile element protein - none - gi|15610980 fig|83332.1.peg.3848 CDS NC_000962 4319278 4319637 1 + 360 FIG091491: hypothetical protein - none - gi|15610981 fig|83332.1.peg.3849 CDS NC_000962 4320701 4321324 2 + 624 Superoxide dismutase [Mn/Fe] (EC 1.15.1.1) Mycobacterium virulence operon involved in an unknown function with Superoxide dismutase;
Oxidative stress gi|15610982 fig|83332.1.peg.3850 CDS NC_000962 4321535 4322068 2 + 534 FIG017534: hypothetical protein Mycobacterium virulence operon involved in an unknown function with Superoxide dismutase gi|15610983 fig|83332.1.peg.3851 CDS NC_000962 4322323 4323231 1 + 909 FIG037441: Conserved transmembrane protein Mycobacterium virulence operon involved in an unknown function with Superoxide dismutase gi|15610984 fig|83332.1.peg.3852 CDS NC_000962 4323496 4323894 1 + 399 ESX-1 secreted protein regulator EspR Mycobacterium virulence operon involved in an Esx-1 secretion system gi|15610985 fig|83332.1.peg.3853 CDS NC_000962 4324012 4324668 1 + 657 FIG022958: hypothetical protein - none - gi|15610986 fig|83332.1.peg.3854 CDS NC_000962 4324680 4324964 3 + 285 Possible membrane protein - none - gi|15610987 fig|83332.1.peg.3855 CDS NC_000962 4325071 4325475 1 + 405 POSSIBLE HISTONE-LIKE PROTEIN HNS - none - gi|15610988 fig|83332.1.peg.3856 CDS NC_000962 4325492 4325965 2 + 474 Ribonuclease E inhibitor RraA RNA processing and degradation, bacterial gi|15610989 fig|83332.1.peg.3857 CDS NC_000962 4327470 4326001 -3 - 1470 Monooxygenase EthA (EC 1.-.-.-) - none - gi|15610990 fig|83332.1.peg.3858 CDS NC_000962 4327546 4328196 1 + 651 Transcriptional repressor EthR, TetR family - none - gi|15610991 fig|83332.1.peg.3859 CDS NC_000962 4329405 4328398 -3 - 1008 DNA-dependent DNA polymerase beta chain - none - gi|15610992 fig|83332.1.peg.3860 CDS NC_000962 4329611 4329414 -2 - 198 Possible membrane protein - none - gi|15610993 fig|83332.1.peg.3861 CDS NC_000962 4331502 4330036 -3 - 1467 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) Ammonia assimilation;
Glutamine, Glutamate, Aspartate and Asparagine Biosynthesis gi|15610994 fig|83332.1.peg.3862 CDS NC_000962 4336078 4331495 -1 - 4584 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) Ammonia assimilation;
Glutamine, Glutamate, Aspartate and Asparagine Biosynthesis gi|15610995 fig|83332.1.peg.3863 CDS NC_000962 4336774 4337946 1 + 1173 Antiactivator of flagellar biosynthesis FleN, an ATPase - none - gi|15610996 fig|83332.1.peg.3864 CDS NC_000962 4337943 4338269 3 + 327 hypothetical protein Rv3861 - none - gi|15610997 fig|83332.1.peg.3865 CDS NC_000962 4338518 4338168 -2 - 351 Transcriptional regulator WhiB-like WhiB6 - none - gi|15610998 fig|83332.1.peg.3866 CDS NC_000962 4338846 4340024 3 + 1179 Probable forkhead-associated protein - none - gi|15610999 fig|83332.1.peg.3867 CDS NC_000962 4340267 4341475 2 + 1209 FIG034615: hypothetical protein - none - gi|15611000 fig|83332.1.peg.3868 CDS NC_000962 4341563 4341874 2 + 312 RD1 region associated protein Rv3865 ESAT-6 proteins secretion system in Actinobacteria gi|15611001 fig|83332.1.peg.3869 CDS NC_000962 4341877 4342728 1 + 852 RD1 region associated protein Rv3866 ESAT-6 proteins secretion system in Actinobacteria gi|15611002 fig|83332.1.peg.3870 CDS NC_000962 4342767 4343318 3 + 552 RD1 region associated protein Rv3867 ESAT-6 proteins secretion system in Actinobacteria gi|15611003 fig|83332.1.peg.3871 CDS NC_000962 4343311 4345032 1 + 1722 AAA family ATPase, ESX-1 secretion system component Rv3868 ESAT-6 proteins secretion system in Actinobacteria gi|15611004 fig|83332.1.peg.3872 CDS NC_000962 4345036 4346478 1 + 1443 Putative ESX-1 secretion system component Rv3869 ESAT-6 proteins secretion system in Actinobacteria gi|15611005 fig|83332.1.peg.3873 CDS NC_000962 4346478 4348721 3 + 2244 FtsK/SpoIIIE family protein Rv3870, component of ESX-1 secretion system ESAT-6 proteins secretion system in Actinobacteria gi|15611006 fig|83332.1.peg.3874 CDS NC_000962 4348824 4350599 3 + 1776 FtsK/SpoIIIE family protein Rv3871, component of ESX-1 secretion system ESAT-6 proteins secretion system in Actinobacteria gi|15611007 fig|83332.1.peg.3875 CDS NC_000962 4350742 4351041 1 + 300 Protein PE35, involved in regulation of esxAB expression ESAT-6 proteins secretion system in Actinobacteria gi|15611008 fig|83332.1.peg.3876 CDS NC_000962 4351072 4352178 1 + 1107 Putative ESX-1 secretion system gating protein PPE68 ESAT-6 proteins secretion system in Actinobacteria gi|15611009 fig|83332.1.peg.3877 CDS NC_000962 4352271 4352573 3 + 303 10 kDa culture filtrate antigen CFP-10 (EsxB) ESAT-6 proteins secretion system in Actinobacteria gi|15611010 fig|83332.1.peg.3878 CDS NC_000962 4352606 4352893 2 + 288 6 kDa early secretory antigenic target ESAT-6 (EsxA) ESAT-6 proteins secretion system in Actinobacteria gi|15611011 fig|83332.1.peg.3879 CDS NC_000962 4353007 4355007 1 + 2001 RD1 region associated protein Rv3876 ESAT-6 proteins secretion system in Actinobacteria gi|15611012 fig|83332.1.peg.3880 CDS NC_000962 4355004 4356539 3 + 1536 Putative ESX-1 secretion system component Rv3877 ESAT-6 proteins secretion system in Actinobacteria gi|15611013 fig|83332.1.peg.3881 CDS NC_000962 4356690 4357532 3 + 843 RD1 region associated protein Rv3878 ESAT-6 proteins secretion system in Actinobacteria gi|15611014 fig|83332.1.peg.3882 CDS NC_000962 4359779 4357590 -2 - 2190 RD1 region associated protein Rv3879c ESAT-6 proteins secretion system in Actinobacteria gi|15611015 fig|83332.1.peg.3883 CDS NC_000962 4360543 4360196 -1 - 348 hypothetical protein Rv3880c - none - gi|15611016 fig|83332.1.peg.3884 CDS NC_000962 4361922 4360540 -3 - 1383 FIG028708: hypothetical protein - none - gi|15611017 fig|83332.1.peg.3885 CDS NC_000962 4363417 4362029 -1 - 1389 Type VII secretion protein EccE PPE gene cluster in Mycobacteria gi|15611018 fig|83332.1.peg.3886 CDS NC_000962 4364754 4363414 -3 - 1341 Type VII secretion-associated serine protease mycosin PPE gene cluster in Mycobacteria gi|15611019 fig|83332.1.peg.3887 CDS NC_000962 4366835 4364976 -2 - 1860 hypothetical protein Rv3884c - none - gi|15611020 fig|83332.1.peg.3888 CDS NC_000962 4368518 4366905 -2 - 1614 hypothetical protein Rv3885c - none - gi|15611021 fig|83332.1.peg.3889 CDS NC_000962 4370167 4368515 -1 - 1653 hypothetical protein Rv3886c - none - gi|15611022 fig|83332.1.peg.3890 CDS NC_000962 4371681 4370152 -3 - 1530 hypothetical protein Rv3887c - none - gi|15611023 fig|83332.1.peg.3891 CDS NC_000962 4372703 4371678 -2 - 1026 Antiactivator of flagellar biosynthesis FleN, an ATPase - none - gi|15611024 fig|83332.1.peg.3892 CDS NC_000962 4373627 4372797 -2 - 831 hypothetical protein Rv3889c - none - gi|15611025 fig|83332.1.peg.3893 CDS NC_000962 4374010 4373723 -1 - 288 Esat-6 like protein EsxC - none - gi|15611026 fig|83332.1.peg.3894 CDS NC_000962 4374369 4374046 -3 - 324 Esat-6 like protein EsxD - none - gi|15611027 fig|83332.1.peg.3895 CDS NC_000962 4375680 4374481 -3 - 1200 PPE family protein CBSS-164757.7.peg.5020 gi|15611028 fig|83332.1.peg.3896 CDS NC_000962 4375992 4375759 -3 - 234 PE family protein - none - gi|15611029 fig|83332.1.peg.3897 CDS NC_000962 4380449 4376259 -2 - 4191 Type VII secretion protein EccCa / Type VII secretion protein EccCb - none - gi|15611030 fig|83332.1.peg.3898 CDS NC_000962 4381937 4380450 -2 - 1488 Type VII secretion protein EccB, Actinobacterial - none - gi|15611031 fig|83332.1.peg.3899 CDS NC_000962 4382848 4381940 -1 - 909 SLT domain protein - none - gi|15611032 fig|83332.1.peg.3900 CDS NC_000962 4383637 4383005 -1 - 633 hypothetical protein Rv3897c - none - gi|15611033 fig|83332.1.peg.3901 CDS NC_000962 4383982 4383650 -1 - 333 hypothetical protein Rv3898c - none - gi|15611034 fig|83332.1.peg.3902 CDS NC_000962 4385376 4384144 -3 - 1233 hypothetical protein Rv3899c - none - gi|15611035 fig|83332.1.peg.3903 CDS NC_000962 4386305 4385370 -2 - 936 hypothetical protein Rv3900c - none - gi|15611036 fig|83332.1.peg.3904 CDS NC_000962 4386811 4386362 -1 - 450 hypothetical protein Rv3901c - none - gi|15611037 fig|83332.1.peg.3905 CDS NC_000962 4387892 4387362 -2 - 531 hypothetical protein Rv3902c - none - gi|15611038 fig|83332.1.peg.3906 CDS NC_000962 4390429 4387889 -1 - 2541 hypothetical protein Rv3903c - none - gi|15611039 fig|83332.1.peg.3907 CDS NC_000962 4390706 4390434 -2 - 273 hypothetical protein Rv3904c - none - gi|15611040 fig|83332.1.peg.3908 CDS NC_000962 4391028 4390717 -3 - 312 hypothetical protein Rv3905c - none - gi|15611041 fig|83332.1.peg.3909 CDS NC_000962 4391603 4391094 -2 - 510 FIG00820046: hypothetical protein - none - gi|15611042 fig|83332.1.peg.3910 CDS NC_000962 4393070 4391628 -2 - 1443 tRNA nucleotidyltransferase (EC 2.7.7.21) (EC 2.7.7.25) tRNA nucleotidyltransferase gi|15611043 fig|83332.1.peg.3911 CDS NC_000962 4393446 4394192 3 + 747 MutT/nudix family protein - none - gi|15611044 fig|83332.1.peg.3912 CDS NC_000962 4394189 4396597 2 + 2409 Possible membrane protein - none - gi|15611045 fig|83332.1.peg.3913 CDS NC_000962 4396594 4400148 1 + 3555 Integral membrane protein MviN - none - gi|15611046 fig|83332.1.peg.3914 CDS NC_000962 4400183 4400851 2 + 669 RNA polymerase sigma-70 factor, ECF subfamily - none - gi|15611047 fig|83332.1.peg.3915 CDS NC_000962 4400867 4401631 2 + 765 FIG00822885: hypothetical protein - none - gi|15611048 fig|83332.1.peg.3916 CDS NC_000962 4401725 4402732 2 + 1008 Thioredoxin reductase (EC 1.8.1.9) Thioredoxin-disulfide reductase;
pyrimidine conversions gi|15611049 fig|83332.1.peg.3917 CDS NC_000962 4402729 4403079 1 + 351 Thioredoxin reductase (EC 1.8.1.9) - none - gi|15611050 fig|83332.1.peg.3918 CDS NC_000962 4403189 4404409 2 + 1221 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) Murein Hydrolases;
Recycling of Peptidoglycan Amino Acids gi|15611051 fig|83332.1.peg.3919 CDS NC_000962 4405164 4404430 -3 - 735 FIG007808: hypothetical protein - none - gi|15611052 fig|83332.1.peg.3920 CDS NC_000962 4406488 4405454 -1 - 1035 Chromosome (plasmid) partitioning protein ParB / Stage 0 sporulation protein J Bacterial Cytoskeleton;
Bacterial Cytoskeleton;
RNA modification and chromosome partitioning cluster gi|15611053 fig|83332.1.peg.3921 CDS NC_000962 4407528 4406485 -3 - 1044 Chromosome (plasmid) partitioning protein ParA / Sporulation initiation inhibitor protein Soj Bacterial Cell Division;
Bacterial Cytoskeleton;
Bacterial Cytoskeleton;
RNA modification and chromosome partitioning cluster;
Ribosome post-transcriptional modification and chromosomal segregation cluster gi|15611054 fig|83332.1.peg.3922 CDS NC_000962 4408199 4407525 -2 - 675 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB RNA modification and chromosome partitioning cluster gi|15611055 fig|83332.1.peg.3923 CDS NC_000962 4408894 4408331 -1 - 564 RNA-binding protein Jag Mycobacterium virulence operon involved in an unknown function with a Jag Protein and YidC and YidD;
tRNA modification Bacteria gi|15611056 fig|83332.1.peg.3924 CDS NC_000962 4410066 4408966 -3 - 1101 Inner membrane protein translocase component YidC, long form CTP synthase (EC 6.3.4.2) cluster;
Mycobacterium virulence operon involved in an unknown function with a Jag Protein and YidC and YidD;
RNA modification cluster gi|15611057 fig|83332.1.peg.3925 CDS NC_000962 4410412 4410050 -1 - 363 Protein YidD Mycobacterium virulence operon involved in an unknown function with a Jag Protein and YidC and YidD;
RNA modification cluster gi|15611058 fig|83332.1.peg.3926 CDS NC_000962 4410786 4410409 -3 - 378 Ribonuclease P protein component (EC 3.1.26.5) RNA modification cluster;
tRNA processing gi|15611059 fig|83332.1.peg.3927 CDS NC_000962 4410926 4410783 -2 - 144 LSU ribosomal protein L34p RNA modification cluster;
Ribosome LSU bacterial gi|15611060 fig|83332.1.peg.3928 CDS NC_000962 1094884 1095057 1 + 174 LSU ribosomal protein L32p Ribosome LSU bacterial fig|83332.1.peg.3929 CDS NC_000962 3110734 3110504 -1 - 231 Programmed cell death antitoxin YdcD MazEF toxin-antitoxing (programmed cell death) system;
Phd-Doc, YdcE-YdcD toxin-antitoxin (programmed cell death) systems fig|83332.1.peg.3930 CDS NC_000962 3556852 3557061 1 + 210 FIG069748: Hypothetical protein CBSS-410289.13.peg.3174 fig|83332.1.peg.3931 CDS NC_000962 3557096 3557281 2 + 186 FIG064496: Hypothetical protein CBSS-410289.13.peg.3174 fig|83332.1.peg.3932 CDS NC_000962 3568802 3568398 -2 - 405 WhiB-family transcriptional regulator WhiB and WhiB-type regulatory proteins fig|83332.1.peg.3933 CDS NC_000962 2234889 2234641 -3 - 249 Programmed cell death antitoxin YdcD MazEF toxin-antitoxing (programmed cell death) system;
Phd-Doc, YdcE-YdcD toxin-antitoxin (programmed cell death) systems fig|83332.1.peg.3934 CDS NC_000962 3669453 3668947 -3 - 507 Serine-protein kinase RsbW (EC 2.7.11.1) - none - fig|83332.1.peg.3935 CDS NC_000962 87799 87206 -1 - 594 hypothetical protein - none - fig|83332.1.peg.3936 CDS NC_000962 800392 800102 -1 - 291 hypothetical protein - none - fig|83332.1.peg.3937 CDS NC_000962 932127 931576 -3 - 552 hypothetical protein - none - fig|83332.1.peg.3938 CDS NC_000962 1214038 1214358 1 + 321 Undecaprenyl diphosphate synthase (EC 2.5.1.31) CBSS-83331.1.peg.3039;
Isoprenoid Biosynthesis;
Isoprenoinds for Quinones fig|83332.1.peg.3939 CDS NC_000962 1286566 1286282 -1 - 285 Pterin-4-alpha-carbinolamine dehydratase (EC 4.2.1.96) Pterin biosynthesis;
Pterin carbinolamine dehydratase fig|83332.1.peg.3940 CDS NC_000962 1445059 1445370 1 + 312 Mb1322, -, len: 104 aa. Equivalent to Rv1290A, len: 104 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 104 aa overlap). Hypothetical unknown protein, equivalent to AAK45590 from Mycobacterium tuberculosis strain CDC1551 (122 aa) but shorter 18 aa. - none - fig|83332.1.peg.3941 CDS NC_000962 1485766 1485311 -1 - 456 Methylmalonyl CoA epimerase (EC 5.1.99.1) - none - fig|83332.1.peg.3942 CDS NC_000962 1999355 1999140 -2 - 216 Transposase subunit B - none - fig|83332.1.peg.3943 CDS NC_000962 2028009 2028311 3 + 303 hypothetical protein - none - fig|83332.1.peg.3944 CDS NC_000962 2142226 2142531 1 + 306 hypothetical protein - none - fig|83332.1.peg.3945 CDS NC_000962 2234214 2233879 -3 - 336 POSSIBLE DEHYDROGENASE (FRAGMENT) - none - fig|83332.1.peg.3946 CDS NC_000962 2453734 2453456 -1 - 279 hypothetical protein - none - fig|83332.1.peg.3947 CDS NC_000962 1962127 1961885 -1 - 243 Tellurite-resistance/Dicarboxylate Transporter (TDT) family - none - fig|83332.1.peg.3948 CDS NC_000962 2487486 2486992 -3 - 495 PROBABLE MEMBRANE PROTEIN - none - fig|83332.1.peg.3949 CDS NC_000962 2579933 2579502 -2 - 432 hypothetical protein Rv2288 - none - fig|83332.1.peg.3950 CDS NC_000962 2680456 2680665 1 + 210 hypothetical protein - none - fig|83332.1.peg.3951 CDS NC_000962 759292 759522 1 + 231 hypothetical protein - none - fig|83332.1.peg.3952 CDS NC_000962 2725859 2725593 -2 - 267 Hydrogen peroxide-inducible genes activator - none - fig|83332.1.peg.3953 CDS NC_000962 2854905 2854681 -3 - 225 Antitoxin 1 Toxin-Antitoxin MT1 fig|83332.1.peg.3954 CDS NC_000962 2930068 2930355 1 + 288 hypothetical protein - none - fig|83332.1.peg.3955 CDS NC_000962 2960101 2959844 -1 - 258 hypothetical protein - none - fig|83332.1.peg.3956 CDS NC_000962 3167865 3168197 3 + 333 [NiFe] hydrogenase nickel incorporation-associated protein HypB - none - fig|83332.1.peg.3957 CDS NC_000962 3168209 3168424 2 + 216 [NiFe] hydrogenase nickel incorporation-associated protein HypB - none - fig|83332.1.peg.3958 CDS NC_000962 3331851 3332045 3 + 195 LSU ribosomal protein L28p Ribosome LSU bacterial fig|83332.1.peg.3959 CDS NC_000962 3392809 3393198 1 + 390 hypothetical protein - none - fig|83332.1.peg.3960 CDS NC_000962 3381089 3380676 -2 - 414 PE family protein - none - fig|83332.1.peg.3961 CDS NC_000962 3701045 3700701 -2 - 345 SECRETED PROTEIN ANTIGEN - none - fig|83332.1.peg.3962 CDS NC_000962 3503274 3502942 -3 - 333 hypothetical protein - none - fig|83332.1.peg.3963 CDS NC_000962 3585946 3585674 -1 - 273 putative ATP-binding protein - none - fig|83332.1.peg.3964 CDS NC_000962 3598352 3598182 -2 - 171 POSSIBLE ANTI-SIGMA FACTOR - none - fig|83332.1.peg.3965 CDS NC_000962 3811904 3812341 2 + 438 PROBABLE MEMBRANE PROTEIN - none - fig|83332.1.peg.3966 CDS NC_000962 3846998 3846678 -2 - 321 hypothetical protein Rv3424c - none - fig|83332.1.peg.3967 CDS NC_000962 4107167 4107523 2 + 357 Transposase - none - fig|83332.1.peg.3968 CDS NC_000962 1338830 1338603 -2 - 228 hypothetical protein - none - fig|83332.1.peg.3969 CDS NC_000962 1792389 1792288 -3 - 102 hypothetical protein - none - fig|83332.1.peg.3970 CDS NC_000962 2249455 2249258 -1 - 198 Phosphoenolpyruvate synthase (EC 2.7.9.2) Glycolysis and Gluconeogenesis;
Inteins fig|83332.1.peg.3971 CDS NC_000962 2270561 2270445 -2 - 117 hypothetical protein - none - fig|83332.1.peg.3972 CDS NC_000962 4053546 4052938 -3 - 609 FIG069547: hypothetical protein Mycobacterium virulence operon involved in an Esx-1 secretion system fig|83332.1.peg.3973 CDS NC_000962 791656 791844 1 + 189 Mycofactocin precursor Mycofactocin system cluster fig|83332.1.rna.1 RNA NC_000962 10887 10957 3 + 71 tRNA-Ile - none - fig|83332.1.rna.2 RNA NC_000962 11112 11181 3 + 70 tRNA-Ala - none - fig|83332.1.rna.3 RNA NC_000962 25644 25723 3 + 80 tRNA-Leu - none - fig|83332.1.rna.4 RNA NC_000962 386272 386205 -1 - 68 tRNA-Gly - none - fig|83332.1.rna.5 RNA NC_000962 658107 658184 3 + 78 tRNA-Tyr - none - fig|83332.1.rna.6 RNA NC_000962 731492 731561 2 + 70 tRNA-Thr - none - fig|83332.1.rna.7 RNA NC_000962 731601 731671 3 + 71 tRNA-Met - none - fig|83332.1.rna.8 RNA NC_000962 733522 733591 1 + 70 tRNA-Trp - none - fig|83332.1.rna.9 RNA NC_000962 850711 850643 -1 - 69 tRNA-Thr - none - fig|83332.1.rna.10 RNA NC_000962 923873 923804 -2 - 70 tRNA-Lys - none - fig|83332.1.rna.11 RNA NC_000962 923997 924067 3 + 71 tRNA-Glu - none - fig|83332.1.rna.12 RNA NC_000962 924108 924178 3 + 71 tRNA-Asp - none - fig|83332.1.rna.13 RNA NC_000962 924211 924281 1 + 71 tRNA-Phe - none - fig|83332.1.rna.14 RNA NC_000962 1025391 1025322 -3 - 70 tRNA-Arg - none - fig|83332.1.rna.15 RNA NC_000962 1113509 1113578 2 + 70 tRNA-Ala - none - fig|83332.1.rna.16 RNA NC_000962 1138145 1138077 -2 - 69 tRNA-Gln - none - fig|83332.1.rna.17 RNA NC_000962 1177394 1177464 2 + 71 tRNA-Leu - none - fig|83332.1.rna.18 RNA NC_000962 1446263 1446194 -2 - 70 tRNA-Arg - none - fig|83332.1.rna.19 RNA NC_000962 1471844 1473381 2 + 1538 SSU rRNA - none - fig|83332.1.rna.20 RNA NC_000962 1473656 1476790 2 + 3135 LSU rRNA - none - fig|83332.1.rna.21 RNA NC_000962 1476897 1477008 3 + 112 5S rRNA - none - fig|83332.1.rna.22 RNA NC_000962 1512726 1512806 3 + 81 tRNA-Leu - none - fig|83332.1.rna.23 RNA NC_000962 1828086 1828016 -3 - 71 tRNA-Leu - none - fig|83332.1.rna.24 RNA NC_000962 1946611 1946681 1 + 71 tRNA-Pro - none - fig|83332.1.rna.25 RNA NC_000962 2401985 2402067 2 + 83 tRNA-Leu - none - fig|83332.1.rna.26 RNA NC_000962 2510667 2510599 -3 - 69 tRNA-Val - none - fig|83332.1.rna.27 RNA NC_000962 2581835 2581765 -2 - 71 tRNA-Met - none - fig|83332.1.rna.28 RNA NC_000962 2619477 2619408 -3 - 70 tRNA-Asn - none - fig|83332.1.rna.29 RNA NC_000962 2765402 2765332 -2 - 71 tRNA-Pro - none - fig|83332.1.rna.30 RNA NC_000962 2765539 2765606 1 + 68 tRNA-Gly - none - fig|83332.1.rna.31 RNA NC_000962 2794174 2794244 1 + 71 tRNA-Arg - none - fig|83332.1.rna.32 RNA NC_000962 2827852 2827921 1 + 70 tRNA-His - none - fig|83332.1.rna.33 RNA NC_000962 2835492 2835561 3 + 70 tRNA-Lys - none - fig|83332.1.rna.34 RNA NC_000962 2969565 2969497 -3 - 69 tRNA-Val - none - fig|83332.1.rna.35 RNA NC_000962 2969750 2969819 2 + 70 tRNA-Gly - none - fig|83332.1.rna.36 RNA NC_000962 2969852 2969919 2 + 68 tRNA-Cys - none - fig|83332.1.rna.37 RNA NC_000962 2969939 2970007 2 + 69 tRNA-Val - none - fig|83332.1.rna.38 RNA NC_000962 3348616 3348547 -1 - 70 tRNA-Glu - none - fig|83332.1.rna.39 RNA NC_000962 3348727 3348659 -1 - 69 tRNA-Gln - none - fig|83332.1.rna.40 RNA NC_000962 3431909 3431840 -2 - 70 tRNA-Ala - none - fig|83332.1.rna.41 RNA NC_000962 3559440 3559370 -3 - 71 tRNA-Phe - none - fig|83332.1.rna.42 RNA NC_000962 4081434 4081365 -3 - 70 tRNA-Thr - none - fig|83332.1.rna.43 RNA NC_000962 4126538 4126608 2 + 71 tRNA-Pro - none - fig|83332.1.rna.44 RNA NC_000962 4168342 4168424 1 + 83 tRNA-Ser - none - fig|83332.1.rna.45 RNA NC_000962 4199214 4199131 -3 - 84 tRNA-Ser - none - fig|83332.1.rna.46 RNA NC_000962 4216934 4216865 -2 - 70 tRNA-Arg - none - fig|83332.1.rna.47 RNA NC_000962 4217053 4216968 -1 - 86 tRNA-Ser - none - fig|83332.1.rna.48 RNA NC_000962 4222664 4222581 -2 - 84 tRNA-Ser - none - fig|83332.1.rna.49 RNA NC_000962 79200 79093 -3 - 108 Glycine riboswitch - none - fig|83332.1.rna.50 RNA NC_000962 79292 79202 -2 - 91 Glycine riboswitch - none - fig|83332.1.rna.51 RNA NC_000962 309865 309683 -1 - 183 - none - fig|83332.1.rna.52 RNA NC_000962 501045 501143 3 + 99 - none - fig|83332.1.rna.53 RNA NC_000962 510324 510224 -3 - 101 - none - fig|83332.1.rna.54 RNA NC_000962 965765 965543 -2 - 223 - none - fig|83332.1.rna.55 RNA NC_000962 1261695 1261477 -3 - 219 - none - fig|83332.1.rna.56 RNA NC_000962 1735507 1735676 1 + 170 - none - fig|83332.1.rna.57 RNA NC_000962 2500746 2500400 -3 - 347 - none - fig|83332.1.rna.58 RNA NC_000962 3468331 3467965 -1 - 367 Transfer-messenger RNA (tmRNA) involved in trans-translation - none - fig|83332.1.rna.59 RNA NC_000962 4168283 4168178 -2 - 106 Bacterial signal recognition particle 4.5S RNA - none - fig|83332.1.rna.60 RNA NC_000962 4322169 4322276 3 + 108 - none - fig|83332.1.rsw.1 RSW NC_000962 168419 168309 -2 - 111 TPP riboswitch (THI element) - none - fig|83332.1.rsw.2 RSW NC_000962 159140 159250 2 + 111 TPP riboswitch (THI element) - none - fig|83332.1.rsw.3 RSW NC_000962 155440 155547 1 + 108 yybP-ykoY leader - none - fig|83332.1.rsw.4 RSW NC_000962 227910 227692 -3 - 219 Cobalamin riboswitch - none - fig|83332.1.rsw.5 RSW NC_000962 309867 309685 -3 - 183 Cobalamin riboswitch - none - fig|83332.1.rsw.6 RSW NC_000962 79202 79095 -2 - 108 Glycine riboswitch - none - fig|83332.1.rsw.7 RSW NC_000962 79294 79204 -1 - 91 Glycine riboswitch - none - fig|83332.1.rsw.8 RSW NC_000962 344356 344453 1 + 98 Glycine riboswitch - none - fig|83332.1.rsw.9 RSW NC_000962 344457 344587 3 + 131 Glycine riboswitch - none -