"ecocyc" "kegg" "pval" "padj" "keggSizes" "ecocycSizes" "overlap" "ecocycFraction" "combined" "2" "\"superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass\"" "eco01200 Carbon metabolism" 8.80536794822333e-65 2.25989768391152e-60 109 43 40 0.930232558139535 152 "3" "superpathway of lipopolysaccharide biosynthesis" "eco00540 Lipopolysaccharide biosynthesis" 4.71424978100489e-50 8.06608137529937e-46 37 25 23 0.92 62 "4" "superpathway of aromatic amino acid biosynthesis" "eco00400 Phenylalanine, tyrosine and tryptophan biosynthesis" 2.05895956083234e-49 2.6421598564381e-45 21 20 19 0.95 41 "5" "TCA cycle I (prokaryotic)" "eco00020 Citrate cycle (TCA cycle)" 4.59490474154504e-47 4.71712920767014e-43 29 21 20 0.952380952380952 50 "10" "superpathway of chorismate metabolism" "eco01110 Biosynthesis of secondary metabolites" 1.57312716891972e-38 8.07486175806495e-35 334 56 43 0.767857142857143 390 "11" "NADH to cytochrome _bo_ oxidase electron transfer I" "eco00190 Oxidative phosphorylation" 1.21354623091735e-36 4.79164061792211e-33 43 17 17 1 60 "13" "mixed acid fermentation" "eco00620 Pyruvate metabolism" 1.17377442668435e-36 4.79164061792211e-33 55 33 22 0.666666666666667 88 "15" "superpathway of purine nucleotides _de novo_ biosynthesis II" "eco00230 Purine metabolism" 1.09492875025223e-35 3.74684618336314e-32 78 24 21 0.875 102 "16" "superpathway of pyrimidine deoxyribonucleotides _de novo_ biosynthesis" "eco00240 Pyrimidine metabolism" 2.04795758586227e-35 6.5701039301444e-32 51 23 19 0.826086956521739 74 "21" "glycolysis I (from glucose 6-phosphate)" "eco00010 Glycolysis / Gluconeogenesis" 4.7887691834977e-32 1.17051201042351e-28 44 18 16 0.888888888888889 62 "22" "\"superpathway of L-lysine, L-threonine and L-methionine biosynthesis I\"" "eco01230 Biosynthesis of amino acids" 1.69786541896011e-31 3.96142872523738e-28 117 19 19 1 136 "24" "superpathway of phospholipid biosynthesis I (bacteria)" "eco00564 Glycerophospholipid metabolism" 1.93365474180265e-29 4.13560407903042e-26 29 14 13 0.928571428571429 43 "31" "3-phenylpropanoate and 3-(3-hydroxyphenyl)propanoate degradation" "eco01220 Degradation of aromatic compounds" 3.9116443266418e-28 6.4769259124685e-25 17 12 11 0.916666666666667 29 "32" "superpathway of phenylethylamine degradation" "eco00360 Phenylalanine metabolism" 6.0973900074208e-28 9.78059465877842e-25 30 12 12 1 42 "34" "superpathway of fatty acid biosynthesis I (E. coli)" "eco00061 Fatty acid biosynthesis" 3.38437705851305e-27 5.10941395333749e-24 13 11 10 0.909090909090909 24 "35" "superpathway of branched chain amino acid biosynthesis" "eco00290 Valine, leucine and isoleucine biosynthesis" 4.18006514523058e-27 6.13036411156244e-24 16 14 11 0.785714285714286 30 "37" "superpathway of tetrahydrofolate biosynthesis" "eco00790 Folate biosynthesis" 2.03748275264939e-26 2.82659431604035e-23 26 11 11 1 37 "39" "biotin biosynthesis I" "eco00780 Biotin metabolism" 7.09999600776255e-26 9.34468705329364e-23 14 12 10 0.833333333333333 26 "44" "L-histidine biosynthesis" "eco00340 Histidine metabolism" 2.41281593558483e-25 2.81476913576294e-22 8 8 8 1 16 "48" "superpathway of thiamine diphosphate biosynthesis I" "eco00730 Thiamine metabolism" 9.21691034753184e-25 9.85633350289186e-22 15 13 10 0.769230769230769 28 "51" "L-lysine biosynthesis I" "eco00300 Lysine biosynthesis" 3.45370090759458e-24 3.47604838405548e-21 13 10 9 0.9 23 "56" "peptidoglycan biosynthesis I (_meso_diaminopimelate containing)" "eco00550 Peptidoglycan biosynthesis" 2.31567751310729e-23 2.1225665490678e-20 24 11 10 0.909090909090909 35 "58" "pentose phosphate pathway" "eco00030 Pentose phosphate pathway" 6.94426077052922e-23 6.14567078191836e-20 32 10 10 1 42 "60" "superpathway of pyridoxal 5'-phosphate biosynthesis and salvage" "eco00750 Vitamin B6 metabolism" 9.76803715827798e-23 8.35655578890681e-20 10 9 8 0.888888888888889 19 "61" "flavin biosynthesis I (bacteria and plants)" "eco00740 Riboflavin metabolism" 1.1943438881145e-22 1.00501101273635e-19 12 8 8 1 20 "63" "folate transformations III (_E. coli_)" "eco00670 One carbon pool by folate" 2.12279134400395e-22 1.72956951885274e-19 14 12 9 0.75 26 "65" "superpathway of coenzyme A biosynthesis I (bacteria)" "eco00770 Pantothenate and CoA biosynthesis" 3.95048118646597e-22 3.11966460463536e-19 23 9 9 1 32 "68" "superpathway of menaquinol-8 biosynthesis I" "eco00130 Ubiquinone and other terpenoid-quinone biosynthesis" 8.10166723189883e-22 6.11556733843187e-19 20 10 9 0.9 30 "71" "(aminomethyl)phosphonate degradation" "eco00440 Phosphonate and phosphinate metabolism" 1.0740586755181e-21 7.7649903963865e-19 9 12 8 0.666666666666667 21 "74" "superpathway of glycol metabolism and degradation" "eco00630 Glyoxylate and dicarboxylate metabolism" 1.58389845298734e-21 1.09866902151136e-18 42 10 10 1 52 "75" "colanic acid building blocks biosynthesis" "eco00520 Amino sugar and nucleotide sugar metabolism" 4.38788675071279e-21 3.00306969218783e-18 46 10 10 1 56 "77" "L-arginine biosynthesis I (via L-ornithine)" "eco00220 Arginine biosynthesis" 5.14294813241771e-21 3.42840944983118e-18 18 12 9 0.75 30 "85" "superpathway of _S_adenosyl-L-methionine biosynthesis" "eco00270 Cysteine and methionine metabolism" 2.53561228153194e-20 1.53121151071805e-17 34 9 9 1 43 "90" "methylerythritol phosphate pathway I" "eco00900 Terpenoid backbone biosynthesis" 5.10853899354946e-20 2.91357007265438e-17 13 11 8 0.727272727272727 24 "91" "superpathway of L-arginine and L-ornithine degradation" "eco00330 Arginine and proline metabolism" 5.39713062533216e-20 3.04433752745385e-17 25 11 9 0.818181818181818 36 "95" "L-lysine degradation I" "eco00310 Lysine degradation" 2.63010592626438e-19 1.42108775994895e-16 17 10 8 0.8 27 "97" "molybdenum cofactor biosynthesis" "eco04122 Sulfur relay system" 4.73231373807089e-19 2.50422334201215e-16 18 10 8 0.8 28 "123" "enterobactin biosynthesis" "eco01053 Biosynthesis of siderophore group nonribosomal peptides" 1.70449615363715e-17 7.11315346066625e-15 7 8 6 0.75 15 "126" "oleate β-oxidation" "eco00071 Fatty acid degradation" 3.12944454548028e-17 1.27487609936113e-14 15 9 7 0.777777777777778 24 "131" "galactitol degradation" "eco00052 Galactose metabolism" 5.08357754597397e-17 1.99190866744155e-14 35 9 8 0.888888888888889 44 "142" "dTDP-L-rhamnose biosynthesis" "eco00523 Polyketide sugar unit biosynthesis" 3.91052753546125e-16 1.41357308729032e-13 6 5 5 1 11 "145" "superpathway of L-aspartate and L-asparagine biosynthesis" "eco00250 Alanine, aspartate and glutamate metabolism" 5.78904263193517e-16 2.04932109170505e-13 33 7 7 1 40 "152" "glycogen degradation I" "eco00500 Starch and sucrose metabolism" 1.1311922384241e-15 3.8200064209414e-13 36 7 7 1 43 "166" "superpathway of sulfate assimilation and cysteine biosynthesis" "eco00920 Sulfur metabolism" 5.56154402058591e-15 1.71972322034142e-12 31 14 8 0.571428571428571 45 "207" "\"L-ascorbate degradation II (bacterial, aerobic)\"" "eco00053 Ascorbate and aldarate metabolism" 5.58423332063866e-13 1.37147701602097e-10 18 5 5 1 23 "215" "dTDP_N_acetylthomosamine biosynthesis" "eco00525 Acarbose and validamycin biosynthesis" 8.79086589971688e-13 2.09876812387194e-10 4 6 4 0.666666666666667 10 "219" "nitrate reduction IX (dissimilatory)" "eco00910 Nitrogen metabolism" 9.73499766145583e-13 2.28172342448643e-10 24 9 6 0.666666666666667 33 "223" "superpathway of L-threonine biosynthesis" "eco00260 Glycine, serine and threonine metabolism" 1.40737829694618e-12 3.22503249920748e-10 37 7 6 0.857142857142857 44 "227" "NAD _de novo_ biosynthesis I (from aspartate)" "eco00760 Nicotinate and nicotinamide metabolism" 1.71633053531393e-12 3.88102406950062e-10 22 5 5 1 27 "229" "tetrapyrrole biosynthesis I (from glutamate)" "eco00860 Porphyrin and chlorophyll metabolism" 1.82043626813127e-12 4.08048007175451e-10 23 10 6 0.6 33 "240" "superpathway of hexuronide and hexuronate degradation" "eco00040 Pentose and glucuronate interconversions" 3.24118399744726e-12 6.93208227454032e-10 34 8 6 0.75 42 "247" "L-homoserine biosynthesis" "eco00261 Monobactam biosynthesis" 4.10240408653453e-12 8.52536039521529e-10 8 4 4 1 12 "261" "2-methylcitrate cycle I" "eco00640 Propanoate metabolism" 7.84776764360706e-12 1.54339430324272e-09 39 8 6 0.75 47 "279" "polymyxin resistance" "eco01503 Cationic antimicrobial peptide (CAMP) resistance" 2.457062661081e-11 4.52046689581676e-09 36 5 5 1 41 "287" "glycerol degradation V" "eco00561 Glycerolipid metabolism" 4.19031274553171e-11 7.49438164557988e-09 13 4 4 1 17 "308" "superpathway of fucose and rhamnose degradation" "eco00051 Fructose and mannose metabolism" 1.74769407107797e-10 2.91263430741664e-08 41 11 6 0.545454545454545 52 "312" "hydrogen to trimethylamine N-oxide electron transfer" "eco00633 Nitrotoluene degradation" 2.57762151840834e-10 4.24068309422757e-08 7 9 4 0.444444444444444 16 "335" "formate to trimethylamine _N_oxide electron transfer" "eco00680 Methane metabolism" 7.24004871140733e-10 1.10700977695876e-07 32 8 5 0.625 40 "355" "\"2-hydroxypenta-2,4-dienoate degradation\"" "eco00621 Dioxin degradation" 1.05402482137605e-09 1.51974983374249e-07 4 4 3 0.75 8 "379" "L-asparagine degradation I" "eco00460 Cyanoamino acid metabolism" 2.30606389714322e-09 3.11500683790425e-07 7 3 3 1 10 "386" "citrate lyase activation" "eco02020 Two-component system" 2.66763598310447e-09 3.54740297960498e-07 170 6 6 1 176 "405" "acetoacetate degradation (to acetyl CoA)" "eco00650 Butanoate metabolism" 3.87061825564533e-09 4.90565024845123e-07 37 4 4 1 41 "484" "Chemotactic Two-Component Signal Transduction" "eco02030 Bacterial chemotaxis" 7.51117955069508e-08 7.94766220261517e-06 20 3 3 1 23 "598" "lipoate biosynthesis and incorporation II" "eco00785 Lipoic acid metabolism" 8.88954688578753e-07 7.63044216801796e-05 3 3 2 0.666666666666667 6 "649" "Rcs Signal Transduction System" "eco02026 Biofilm formation - Escherichia coli" 2.6164600976987e-06 0.000206619841253652 63 3 3 1 66 "650" "autoinducer AI-2 degradation" "eco02024 Quorum sensing" 2.74513846315929e-06 0.000216448475136661 64 3 3 1 67 "665" "alanine racemization" "eco00473 D-Alanine metabolism" 3.55423762917429e-06 0.000273112301654965 4 4 2 0.5 8 "715" "L-threonine degradation III (to methylglyoxal)" "eco00350 Tyrosine metabolism" 1.06579684571968e-05 0.000739288541767448 9 3 2 0.666666666666667 12 "879" "superoxide radicals degradation" "eco00380 Tryptophan metabolism" 6.63657780132479e-05 0.00367878551341255 10 6 2 0.333333333333333 16