Patients admitted with dengue fever to the place of study (Professorial medical unit at Colombo South Teaching Hospital)

Fluid therapy started prior to recruitment

Patients developing fluid leakage during ward stay Age>18 years

Chronic kidney disease*	Heart failure	Chronic liver disease

Excluded from study

Enrolled for the study

*Chronic kidney disease was defined as a previous diagnosis of chronic kidney disease or persistent elevation of serum creatinine with a e-GFR<60ml/min/1.73m2 during hospital stay

Heart failure was defined as a previous diagnosis of heart failure and/or any participant on treatment for heart failure with a left ventricular ejection fraction <40%.

Chronic liver disease was defined as a previous diagnosis of chronic liver disease or biochemical evidence of progressive liver failure persistent for more than 6 months.

Supplementary figure 1: Flow chart demonstrating the recruitment and exclusion of patients in the study.