Table S3. GO and KEGG analyses of the target mRNAs regulated by the five down regulated candidate tRF & tiRNAs. GO.ID Term Ontology Count Pop.Hits List.Total Pop.Total Fold.Enrichment Pvalue FDR Enrichment.Score Gene.Ratio GENES GO:0042594 response to starvation Biological process 13 177 466 17653 2.782291894 8.65E-04 1 3.062993214 0.027896996 ATG14//USP33//STK26//RRAGD//BMPR2//C12ORF66//LARS//PIK3R4//ADM//GCG//GCGR//ACAT1//ULK2// GO:0002029 desensitization of G-protein coupled receptor protein signaling pathway Biological process 4 19 466 17653 7.975152473 1.36E-03 1 2.86783493 0.008583691 ADM//HTR2B//ARRB2//GIPR// GO:0022401 negative adaptation of signaling pathway Biological process 4 19 466 17653 7.975152473 1.36E-03 1 2.86783493 0.008583691 GIPR//ADM//HTR2B//ARRB2// GO:0023058 adaptation of signaling pathway Biological process 4 21 466 17653 7.215614143 2.01E-03 1 2.697285313 0.008583691 GIPR//ADM//HTR2B//ARRB2// GO:0032024 positive regulation of insulin secretion Biological process 7 68 466 17653 3.899614996 2.07E-03 1 2.685059114 0.015021459 MPC2//GCG//ANO1//C2CD2L//ABAT//GIPR//NR0B2// GO:0000910 cytokinesis Biological process 12 172 466 17653 2.642928436 2.09E-03 1 2.680422622 0.025751073 STAMBP//SEPT2//USP8//PIK3R4//AURKA//PRC1//RXFP3//ROPN1B//CNTROB//PAK4//RND1//PACSIN3// GO:0003174 mitral valve development Biological process 3 11 466 17653 10.33144752 2.57E-03 1 2.589259041 0.006437768 BMPR2//ACVR1//GJA5// GO:0090277 positive regulation of peptide hormone secretion Biological process 8 92 466 17653 3.294084717 2.98E-03 1 2.525704329 0.017167382 ABAT//GIPR//NR0B2//MPC2//GCG//ANO1//C2CD2L//EGFR// GO:0060736 prostate gland growth Biological process 3 12 466 17653 9.470493562 3.37E-03 1 2.472858226 0.006437768 AR//UBE3A//PSAPL1// GO:0042310 vasoconstriction Biological process 7 76 466 17653 3.489129207 3.89E-03 1 2.409932804 0.015021459 ADRA2B//ADM//BMPR2//EGFR//GJA5//ARHGAP42//HTR2B// GO:0040034 regulation of development, heterochronic Biological process 3 13 466 17653 8.741994057 0.004291004 1 2.367441096 0.006437768 FGF9//ASCL1//HMGN1// GO:0050714 positive regulation of protein secretion Biological process 14 238 466 17653 2.228351426 0.004454428 1 2.351208055 0.030042918 ABAT//GIPR//NR0B2//MPC2//GCG//ANO1//C2CD2L//C1QTNF3//HTR2B//SAA1//EGFR//ANKRD1//TTN//MYOM1// GO:0035335 peptidyl-tyrosine dephosphorylation Biological process 8 99 466 17653 3.061169636 0.00467589 1 2.330135726 0.017167382 DUSP1//DUSP6//EYA1//EYA2//PTPN14//PTPRO//UBASH3B//CDC25A// GO:0019229 regulation of vasoconstriction Biological process 6 60 466 17653 3.788197425 0.004919813 1 2.308051443 0.012875536 ADRA2B//ADM//BMPR2//EGFR//GJA5//ARHGAP42// GO:0030238 male sex determination Biological process 3 14 466 17653 8.11756591 0.00535525 1 2.271220215 0.006437768 AR//FGF9//DHH// GO:0046887 positive regulation of hormone secretion Biological process 9 126 466 17653 2.705855303 0.006243867 1 2.204546355 0.019313305 ABAT//GIPR//NR0B2//MPC2//GCG//ANO1//C2CD2L//C1QTNF3//EGFR// GO:0002031 G-protein coupled receptor internalization Biological process 3 15 466 17653 7.57639485 0.006564281 1 2.182812864 0.006437768 ADM//HTR2B//ARRB2// GO:0097756 negative regulation of blood vessel diameter Biological process 7 84 466 17653 3.156831187 0.00674007 1 2.171335621 0.015021459 ADRA2B//HTR2B//ADM//BMPR2//EGFR//GJA5//ARHGAP42// GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus Biological process 4 29 466 17653 5.225099896 0.006747644 1 2.170847836 0.008583691 MPC2//GCG//ANO1//C2CD2L// GO:0035556 intracellular signal transduction Biological process 96 2871 466 17653 1.266690884 0.007259513 1 2.139092542 0.206008584 DUSP6//EGFR//FGF9//MAP3K15//STK26//PSMB5//PSMD12//RASGRF2//GADD45A//KIDINS220//ADRA2B//GHR//SAA1//DUSP1//CNOT11//AURKA//CNOT9//CALCRL//ADM//GCG//GCGR//HTR2B//NKIRAS2//STAMBP//STAT2//RND1//RALGPS2//RAPGEF6//RALA//USP8//PAK4//ROPN1B//CELSR1//TTN//MYOM1//NOS1AP//UBE3A//FARP2//STK10//CCDC88A//TBC1D7//RRAGD//ARFGEF3//CYTH2//CYTH1//DNAJC27//SEMA4C//FGD5//ARHGEF40//PLEKHG1//ARHGAP42//CCDC125//GPR20//RIOK3//CTH//GOLT1B//TRIM8//RNF149//LMTK2//AR//JCAD//ANKRD1//GIPR//GRIK2//ITCH//FCGR2B//FLRT3//LRRC4C//NYX//NPR3//PI4KB//FAM13A//RAP1GAP2//ARHGAP28//ARRB2//FAM110C//TXN//C5AR2//XCL1//CDC5L//BRIP1//HNRNPK//NME5//C12ORF66//LARS//BMF//ZBTB33//PPP1R17//DGKB//NSMCE1//TUFT1//CORO2A//CCDC68//HASPIN//SPSB2//RGS11// GO:0008217 regulation of blood pressure Biological process 11 177 466 17653 2.354246987 0.007467909 1 2.126800956 0.02360515 CTSZ//ADM//AR//ARHGAP42//BMPR2//PTPRO//GJA5//ABAT//ADRA2B//GCGR//NPR3// GO:0007266 Rho protein signal transduction Biological process 12 202 466 17653 2.250414312 0.007550848 1 2.122004254 0.025751073 FGD5//ARHGEF40//PLEKHG1//RASGRF2//FARP2//ARHGAP42//CCDC125//GPR20//PAK4//ROPN1B//RND1//CELSR1// GO:0070536 protein K63-linked deubiquitination Biological process 4 30 466 17653 5.0509299 0.007626351 1 2.117683212 0.008583691 STAMBP//USP33//YOD1//USP8// GO:0007076 mitotic chromosome condensation Biological process 3 16 466 17653 7.102870172 0.007922695 1 2.101127036 0.006437768 NCAPD3//NCAPG//TTN// GO:0060413 atrial septum morphogenesis Biological process 3 16 466 17653 7.102870172 0.007922695 1 2.101127036 0.006437768 ACVR1//GJA5//BMPR2// GO:0002793 positive regulation of peptide secretion Biological process 14 259 466 17653 2.047674284 0.009156174 1 2.038285978 0.030042918 ABAT//GIPR//NR0B2//MPC2//GCG//ANO1//C2CD2L//ANKRD1//TTN//MYOM1//C1QTNF3//HTR2B//SAA1//EGFR// GO:0006418 tRNA aminoacylation for protein translation Biological process 5 49 466 17653 3.865507576 0.009209982 1 2.03574124 0.010729614 AARS2//NARS2//LARS//FARSB//LRRC47// GO:0003073 regulation of systemic arterial blood pressure Biological process 7 90 466 17653 2.946375775 0.009725404 1 2.012092339 0.015021459 CTSZ//ARHGAP42//BMPR2//PTPRO//GJA5//ADM//AR// GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway Biological process 8 113 466 17653 2.681909681 0.01018135 1 1.992194636 0.017167382 GPR20//RXFP3//C5AR2//HTR2B//NPR3//P2RY4//ANO1//MCHR2// GO:0035384 thioester biosynthetic process Biological process 5 51 466 17653 3.713919044 0.010871157 1 1.963724235 0.010729614 ACAT1//PDHB//HACD2//ELOVL7//MPC2// GO:0071616 acyl-CoA biosynthetic process Biological process 5 51 466 17653 3.713919044 0.010871157 1 1.963724235 0.010729614 ACAT1//PDHB//HACD2//ELOVL7//MPC2// GO:0016311 dephosphorylation Biological process 21 461 466 17653 1.725643079 0.011199718 1 1.950792917 0.045064378 DUSP1//DUSP6//PTPN14//PTPRO//DUSP27//ITGA2//PPP1R17//MTMR9//ARFGEF3//CSRNP2//EYA1//EYA2//LMTK2//SET//UBASH3B//CDC25A//IMPA2//PHOSPHO1//NT5C2//PFKFB4//CA3// GO:0007507 heart development Biological process 24 550 466 17653 1.653031604 0.011480307 1 1.940046497 0.051502146 AHI1//HTR2B//CHD7//ACVR1//BMPR2//EYA1//GJA5//SIRT6//FLRT3//TTN//MYOM1//CACYBP//SOX6//ANKRD1//FGF9//ADAMTS1//DUSP6//GALNT11//EGFR//ARRB2//CALCRL//ADM//LOX//KAT2B// GO:0007265 Ras protein signal transduction Biological process 21 463 466 17653 1.718188897 0.011714973 1 1.93125871 0.045064378 PAK4//ROPN1B//RND1//CELSR1//FARP2//ARFGEF3//CYTH2//CYTH1//DNAJC27//RALGPS2//FGD5//ARHGEF40//PLEKHG1//RASGRF2//ARHGAP42//CCDC125//GPR20//STAMBP//RAPGEF6//RALA//USP8// GO:0043039 tRNA aminoacylation Biological process 5 52 466 17653 3.642497524 0.011773767 1 1.929084573 0.010729614 FARSB//LARS//AARS2//NARS2//LRRC47// GO:0031667 response to nutrient levels Biological process 21 465 466 17653 1.710798837 0.012249039 1 1.911897978 0.045064378 GCGR//GIPR//GCLM//ATG14//USP33//STK26//RRAGD//BMPR2//CCK//EGFR//ITGA2//C12ORF66//LARS//PIK3R4//ADM//GCG//ACAT1//ULK2//ASCL1//BRIP1//SIRT6// GO:0043038 amino acid activation Biological process 5 53 466 17653 3.573771156 0.012725983 1 1.895308659 0.010729614 FARSB//LARS//AARS2//NARS2//LRRC47// GO:0045292 mRNA cis splicing, via spliceosome Biological process 3 19 466 17653 5.981364355 0.012930282 1 1.88839199 0.006437768 RNF113B//NCBP2//NCBP2L// GO:0046578 regulation of Ras protein signal transduction Biological process 13 244 466 17653 2.018301907 0.01315453 1 1.880924652 0.027896996 ARFGEF3//CYTH2//CYTH1//RALGPS2//FGD5//ARHGEF40//PLEKHG1//RASGRF2//FARP2//ARHGAP42//CCDC125//GPR20//STAMBP// GO:0001707 mesoderm formation Biological process 6 74 466 17653 3.071511426 0.013395595 1 1.873037994 0.012875536 EYA1//EYA2//ITGA2//EXOC4//BMPR2//ACVR1// GO:0060541 respiratory system development Biological process 11 193 466 17653 2.159076253 0.013717469 1 1.862726026 0.02360515 DHCR7//EGFR//LOX//CHD7//HOXA5//BMPR2//ASCL1//CTSZ//FGF9//CELSR1//EDA// GO:0006084 acetyl-CoA metabolic process Biological process 4 36 466 17653 4.20910825 0.014485284 1 1.839072989 0.008583691 ACAT1//PDHB//MPC2//ACOT12// GO:0048585 negative regulation of response to stimulus Biological process 57 1615 466 17653 1.337010856 0.01449106 1 1.838899831 0.122317597 DUSP1//DUSP6//FCGR2B//GIPR//ADM//HTR2B//ARRB2//XCL1//EGFR//LMTK2//RGS17//UBASH3B//RGS11//ACVR1//TRAIP//STAMBP//WIF1//FGF9//SIX3//TBC1D7//CCK//CNOT9//ABAT//ARHGAP42//CCDC125//RIOK3//RNF149//HLX//HIF1AN//DLK1//ITCH//FLRT3//LRRC4C//NYX//NCOA5//SEMA4C//IFIT1//CALCRL//C1QTNF3//MMP26//SAA1//LILRB4//ADAR//C5AR2//PSMB5//PSMD12//PTPRO//NME5//TXN//YOD1//C12ORF66//CTH//GCLM//AR//CX3CR1//EYA1//EYA2// GO:0003283 atrial septum development Biological process 3 20 466 17653 5.682296137 0.014919225 1 1.826253738 0.006437768 GJA5//ACVR1//BMPR2// GO:0006085 acetyl-CoA biosynthetic process Biological process 3 20 466 17653 5.682296137 0.014919225 1 1.826253738 0.006437768 PDHB//MPC2//ACAT1// GO:0051000 positive regulation of nitric-oxide synthase activity Biological process 3 20 466 17653 5.682296137 0.014919225 1 1.826253738 0.006437768 HTR2B//NPR3//NOS1AP// GO:0048332 mesoderm morphogenesis Biological process 6 76 466 17653 2.990682178 0.015133864 1 1.820050162 0.012875536 BMPR2//ACVR1//EYA1//EYA2//ITGA2//EXOC4// GO:0009887 animal organ morphogenesis Biological process 38 1001 466 17653 1.438076945 0.015693854 1 1.804270392 0.081545064 EYA1//AHI1//PHOSPHO1//HTR2B//CHD7//ACVR1//BMPR2//GJA5//SIRT6//SIX3//COL27A1//EGFR//FGF9//PRRX1//CELSR1//ADM//EDA//TUFT1//ITGA2//FAM20A//EXOC4//HLX//HMGN1//AR//HOXA5//ANKRD1//TTN//MYOM1//ARRB2//PSMB5//PSMD12//ADAMTS1//CTSZ//WDR72//LIMS2//HCCS//SEMA6A//ASXL3// GO:1903532 positive regulation of secretion by cell Biological process 17 361 466 17653 1.783915685 0.015832538 1 1.800449463 0.036480687 CCK//ABAT//GIPR//NR0B2//MPC2//GCG//ANO1//C2CD2L//SYT1//CACNA1H//ANKRD1//TTN//MYOM1//C1QTNF3//HTR2B//SAA1//EGFR// GO:2000177 regulation of neural precursor cell proliferation Biological process 6 77 466 17653 2.951842149 0.016059097 1 1.794278892 0.012875536 CX3CR1//OTP//SIX3//LIMS2//CTSZ//ASCL1// GO:0043112 receptor metabolic process Biological process 10 172 466 17653 2.202440363 0.016141508 1 1.792055886 0.021459227 LMTK2//ADM//HTR2B//ARRB2//AHI1//HOXA5//CALCRL//PIK3R4//HNRNPK//ITCH// GO:0010646 regulation of cell communication Biological process 112 3522 466 17653 1.204651083 0.016225097 1 1.7898127 0.240343348 GADD45A//STK26//EGFR//MAP3K15//KIDINS220//ADRA2B//DUSP6//GHR//SAA1//DUSP1//LIFR//GIPR//ADM//HTR2B//ARRB2//GCG//USP33//RIC8B//RGS11//GALNT11//GPC5//LMTK2//RGS17//UBASH3B//ACVR1//FCGR2B//FGF9//XCL1//CCK//GJA5//NOS1AP//TRAIP//BMPR2//STAMBP//UBE3A//WIF1//SIX3//TBC1D7//RRAGD//ARFGEF3//CYTH2//CYTH1//ABAT//NR0B2//RALGPS2//SEMA4C//CNOT9//AR//FGD5//ARHGEF40//PLEKHG1//RASGRF2//FARP2//ARHGAP42//CCDC125//GPR20//MPC2//ANO1//C2CD2L//RIOK3//CTH//GOLT1B//TRIM8//PAK4//RNF149//JCAD//ANKRD1//HIF1AN//DLK1//ASCL1//KAT2B//PRRX1//GRIK2//ITCH//FLRT3//LRRC4C//NYX//NCOA5//SYT1//LILRB4//FAM13A//RAP1GAP2//ARHGAP28//FAM110C//TXN//ITGA2//CHD7//STAT2//ADAR//C1QTNF3//C5AR2//DNAJC27//PSMB5//PSMD12//PTPRO//BMF//EDA//USP8//CX3CR1//AURKA//BRIP1//HNRNPK//NME5//C12ORF66//LARS//KLHL24//RWDD1//LIMS2//GCLM//ITM2C//EYA1//EYA2// GO:0003094 glomerular filtration Biological process 3 21 466 17653 5.411710607 0.017071134 1 1.76773764 0.006437768 PTPRO//GJA5//JCHAIN// GO:0048791 calcium ion-regulated exocytosis of neurotransmitter Biological process 4 38 466 17653 3.987576237 0.017421594 1 1.758912104 0.008583691 SYT1//SYT2//C2CD4A//SYT6// GO:0009966 regulation of signal transduction Biological process 103 3215 466 17653 1.213637122 0.017643248 1 1.75342147 0.221030043 GADD45A//STK26//EGFR//MAP3K15//KIDINS220//ADRA2B//DUSP6//GHR//SAA1//DUSP1//LIFR//GIPR//ADM//HTR2B//ARRB2//USP33//RIC8B//RGS11//GALNT11//LMTK2//RGS17//UBASH3B//ACVR1//FCGR2B//FGF9//GCG//XCL1//CCK//NOS1AP//TRAIP//BMPR2//STAMBP//UBE3A//WIF1//SIX3//TBC1D7//RRAGD//ARFGEF3//CYTH2//CYTH1//RALGPS2//SEMA4C//CNOT9//AR//FGD5//ARHGEF40//PLEKHG1//RASGRF2//FARP2//ARHGAP42//CCDC125//GPR20//RIOK3//CTH//GOLT1B//TRIM8//PAK4//RNF149//JCAD//ANKRD1//HIF1AN//DLK1//ASCL1//KAT2B//PRRX1//GRIK2//ITCH//FLRT3//LRRC4C//NYX//NCOA5//LILRB4//FAM13A//RAP1GAP2//ARHGAP28//FAM110C//TXN//STAT2//ADAR//C5AR2//DNAJC27//PSMB5//PSMD12//PTPRO//BMF//EDA//USP8//ABAT//AURKA//BRIP1//HNRNPK//NME5//C12ORF66//LARS//KLHL24//RWDD1//LIMS2//GCLM//ITM2C//CX3CR1//EYA1//EYA2//GPC5// GO:0001704 formation of primary germ layer Biological process 8 125 466 17653 2.424446352 0.017862862 1 1.748048951 0.017167382 DUSP1//BMPR2//ACVR1//EYA1//EYA2//DUSP6//ITGA2//EXOC4// GO:0097755 positive regulation of blood vessel diameter Biological process 5 58 466 17653 3.265687435 0.01826995 1 1.738262649 0.010729614 ADM//BMPR2//ARHGAP42//EGFR//GJA5// GO:0006520 cellular amino acid metabolic process Biological process 17 367 466 17653 1.754750851 0.018291505 1 1.737750567 0.036480687 NFS1//CTH//FARSB//LARS//AARS2//NARS2//LRRC47//ODC1//PSMB5//PSMD12//GCLM//GLYAT//HAL//GHR//ACAT1//ABAT//UPB1// GO:0007162 negative regulation of cell adhesion Biological process 13 255 466 17653 1.931237903 0.018308013 1 1.737358799 0.027896996 PTPRO//FCGR2B//HLX//ITCH//ABAT//UBASH3B//SEMA6A//XCL1//ADAM10//RND1//MIA3//TGFBI//CBLL1// GO:0051056 regulation of small GTPase mediated signal transduction Biological process 16 339 466 17653 1.787939788 0.018530411 1 1.732114959 0.034334764 ARFGEF3//CYTH2//CYTH1//RALGPS2//FGD5//ARHGEF40//PLEKHG1//RASGRF2//FARP2//ARHGAP42//CCDC125//GPR20//STAMBP//FAM13A//RAP1GAP2//ARHGAP28// GO:0023051 regulation of signaling Biological process 113 3575 466 17653 1.197388277 0.018622217 1 1.729968613 0.24248927 GADD45A//STK26//EGFR//MAP3K15//KIDINS220//ADRA2B//DUSP6//GHR//SAA1//DUSP1//LMTK2//LIFR//GIPR//ADM//HTR2B//ARRB2//GCG//USP33//RIC8B//RGS11//GALNT11//GPC5//RGS17//UBASH3B//ACVR1//FCGR2B//FGF9//XCL1//CCK//NOS1AP//TRAIP//BMPR2//STAMBP//UBE3A//WIF1//SIX3//TBC1D7//RRAGD//ARFGEF3//CYTH2//CYTH1//ABAT//NR0B2//RALGPS2//SEMA4C//CNOT9//AR//FGD5//ARHGEF40//PLEKHG1//RASGRF2//FARP2//ARHGAP42//CCDC125//GPR20//MPC2//ANO1//C2CD2L//RIOK3//CTH//GOLT1B//TRIM8//PAK4//RNF149//JCAD//ANKRD1//HIF1AN//DLK1//ASCL1//KAT2B//PRRX1//GRIK2//ITCH//FLRT3//LRRC4C//NYX//NCOA5//SYT1//LILRB4//FAM13A//RAP1GAP2//ARHGAP28//FAM110C//TXN//ITGA2//CHD7//STAT2//ADAR//C1QTNF3//C5AR2//DNAJC27//PSMB5//PSMD12//PTPRO//BMF//EDA//USP8//GJA5//CX3CR1//AURKA//BRIP1//HNRNPK//NME5//ATP1B3//C12ORF66//LARS//KLHL24//RWDD1//LIMS2//GCLM//ITM2C//EYA1//EYA2// GO:0051174 regulation of phosphorus metabolic process Biological process 62 1806 466 17653 1.300488595 0.018729577 1 1.727472023 0.13304721 GADD45A//CDC25A//STK26//EGFR//MAP3K15//KIDINS220//ADRA2B//DUSP6//GHR//SAA1//DUSP1//ROPN1B//ATG14//CCDC88A//STAT2//ARRB2//FAM20A//CDK2AP1//NUPL2//FLRT3//LRRC4C//NYX//UBASH3B//NPR3//PDHB//HTR2B//ITGA2//GCG//TRPC5//BMPR2//ACVR1//PPP1R17//MTMR9//ARFGEF3//CSRNP2//ADM//PAK4//STK10//TXN//LMTK2//SET//SEMA4C//CNOT9//PIFO//AR//RNF149//FGF9//JCAD//PIK3R4//ADAR//KAT2B//SIRT6//PFKFB4//TTN//GRIK2//ITCH//FCGR2B//CCK//C5AR2//DNAJC27//XCL1//ADGRF5// GO:0051301 cell division Biological process 25 607 466 17653 1.560213107 0.01923814 1 1.715836917 0.053648069 STAMBP//SEPT2//USP8//PAK4//RND1//PACSIN3//PRC1//BRIP1//PIK3R4//AURKA//RXFP3//FGF9//HTR2B//ROPN1B//CNTROB//NCAPD3//RALA//NCAPG//SYCP1//WEE1//MCMBP//CDT1//SMC1A//PARD6B//CDC25A// GO:0045665 negative regulation of neuron differentiation Biological process 11 203 466 17653 2.052717816 0.019260792 1 1.715325863 0.02360515 CTSZ//DCC//RAP1GAP2//PTPRO//ITM2C//ULK2//SEMA4C//TRPC5//ZHX2//ASCL1//SIX3// GO:0006637 acyl-CoA metabolic process Biological process 7 103 466 17653 2.574503104 0.019325815 1 1.713862189 0.015021459 ACOT12//ACAT1//PDHB//HACD2//ELOVL7//MPC2//GLYAT// GO:0035383 thioester metabolic process Biological process 7 103 466 17653 2.574503104 0.019325815 1 1.713862189 0.015021459 ACOT12//ACAT1//PDHB//GLYAT//HACD2//ELOVL7//MPC2// GO:0097205 renal filtration Biological process 3 22 466 17653 5.165723761 0.019387104 1 1.712487069 0.006437768 PTPRO//JCHAIN//GJA5// GO:0048729 tissue morphogenesis Biological process 26 639 466 17653 1.541363584 0.01970824 1 1.705352152 0.055793991 ACVR1//EYA1//BMPR2//CELSR1//AHI1//ADM//SEMA4C//RALA//RIPK4//CHD7//SIRT6//FLRT3//SIX3//EYA2//ITGA2//EXOC4//ANKRD1//TTN//MYOM1//ARRB2//PSMB5//PSMD12//CTSZ//HOXA5//AR//EGFR// GO:0007264 small GTPase mediated signal transduction Biological process 24 578 466 17653 1.572953948 0.019757213 1 1.704274326 0.051502146 RAPGEF6//RALA//USP8//PAK4//ROPN1B//RND1//CELSR1//FARP2//ARFGEF3//CYTH2//CYTH1//DNAJC27//RALGPS2//FGD5//ARHGEF40//PLEKHG1//RASGRF2//ARHGAP42//CCDC125//GPR20//STAMBP//FAM13A//RAP1GAP2//ARHGAP28// GO:0015800 acidic amino acid transport Biological process 5 60 466 17653 3.156831187 0.02087184 1 1.680439261 0.010729614 SEPT2//PRAF2//SYT1//CCK//ABAT// GO:0002698 negative regulation of immune effector process Biological process 7 105 466 17653 2.52546495 0.02124006 1 1.672844258 0.015021459 FCGR2B//XCL1//RIOK3//HLX//ARRB2//ITCH//IFIT1// GO:0050687 negative regulation of defense response to virus Biological process 3 23 466 17653 4.941127076 0.02186777 1 1.6601955 0.006437768 RIOK3//IFIT1//ITCH// GO:0007219 Notch signaling pathway Biological process 10 181 466 17653 2.092926754 0.022175201 1 1.654132439 0.021459227 KAT2B//GALNT11//ADAM10//EGFR//HIF1AN//DLK1//ASCL1//GMDS//ITCH//NR0B2// GO:0048488 synaptic vesicle endocytosis Biological process 4 41 466 17653 3.695802366 0.022477387 1 1.648254185 0.008583691 SYT2//C2CD4A//SYT1//STON2// GO:0019220 regulation of phosphate metabolic process Biological process 61 1791 466 17653 1.290229162 0.022727315 1 1.643451868 0.130901288 GADD45A//CDC25A//STK26//EGFR//MAP3K15//KIDINS220//ADRA2B//DUSP6//GHR//SAA1//DUSP1//ROPN1B//ATG14//CCDC88A//STAT2//ARRB2//FAM20A//CDK2AP1//NUPL2//FLRT3//LRRC4C//NYX//UBASH3B//NPR3//HTR2B//ITGA2//GCG//TRPC5//BMPR2//ACVR1//PPP1R17//MTMR9//ARFGEF3//CSRNP2//ADM//PAK4//STK10//TXN//LMTK2//SET//SEMA4C//CNOT9//PIFO//AR//RNF149//FGF9//JCAD//PIK3R4//ADAR//KAT2B//SIRT6//PFKFB4//TTN//GRIK2//ITCH//FCGR2B//CCK//C5AR2//DNAJC27//XCL1//ADGRF5// GO:0009991 response to extracellular stimulus Biological process 21 495 466 17653 1.607114059 0.022842188 1 1.641262306 0.045064378 GCGR//GIPR//GCLM//ATG14//USP33//STK26//RRAGD//BMPR2//SIRT6//CCK//EGFR//ITGA2//C12ORF66//LARS//PIK3R4//ADM//GCG//ACAT1//ULK2//ASCL1//BRIP1// GO:0015837 amine transport Biological process 6 84 466 17653 2.705855303 0.023647303 1 1.626218389 0.012875536 SEPT2//ADRA2B//CCK//ABAT//SYT1//SLC18A2// GO:0014706 striated muscle tissue development Biological process 17 379 466 17653 1.699191457 0.024082579 1 1.618297 0.036480687 MYOM1//GJA5//CHD7//SIRT6//ZBTB18//HLX//ZNF689//ANKRD1//COPS2//TTN//CACYBP//SOX6//FGF9//ACVR1//ARRB2//EYA1//EYA2// GO:0032459 regulation of protein oligomerization Biological process 4 42 466 17653 3.607807071 0.02434094 1 1.613662649 0.008583691 JCHAIN//CCK//RIOK3//BMF// GO:0003171 atrioventricular valve development Biological process 3 24 466 17653 4.735246781 0.024513339 1 1.610597535 0.006437768 GJA5//ACVR1//BMPR2// GO:0007530 sex determination Biological process 3 24 466 17653 4.735246781 0.024513339 1 1.610597535 0.006437768 AR//FGF9//DHH// GO:0032461 positive regulation of protein oligomerization Biological process 3 24 466 17653 4.735246781 0.024513339 1 1.610597535 0.006437768 BMF//JCHAIN//CCK// GO:1902531 regulation of intracellular signal transduction Biological process 64 1901 466 17653 1.275353157 0.024636279 1 1.608424885 0.137339056 GADD45A//STK26//EGFR//MAP3K15//KIDINS220//ADRA2B//DUSP6//GHR//SAA1//DUSP1//NOS1AP//STAMBP//UBE3A//TBC1D7//RRAGD//ARFGEF3//CYTH2//CYTH1//RALGPS2//SEMA4C//FGD5//ARHGEF40//PLEKHG1//RASGRF2//FARP2//ARHGAP42//CCDC125//GPR20//RIOK3//CTH//HTR2B//GOLT1B//TRIM8//PAK4//RNF149//FGF9//LMTK2//AR//JCAD//ANKRD1//GIPR//GRIK2//ITCH//FCGR2B//FLRT3//LRRC4C//NYX//FAM13A//RAP1GAP2//ARHGAP28//ARRB2//FAM110C//TXN//GCG//C5AR2//DNAJC27//XCL1//AURKA//BRIP1//HNRNPK//NME5//C12ORF66//LARS//BMF// GO:0035023 regulation of Rho protein signal transduction Biological process 8 133 466 17653 2.278614992 0.024872491 1 1.604280723 0.017167382 ARHGAP42//CCDC125//GPR20//FGD5//ARHGEF40//PLEKHG1//RASGRF2//FARP2// GO:0001708 cell fate specification Biological process 6 85 466 17653 2.674021712 0.024897776 1 1.603839452 0.012875536 EYA1//EYA2//ASCL1//SOX6//DUSP6//AR// GO:0048638 regulation of developmental growth Biological process 15 323 466 17653 1.75922481 0.02513096 1 1.599790923 0.032188841 GHR//FTO//PLAC8//CHD7//TRPC5//HLX//DCC//ULK2//BMPR2//SEMA4C//FGF9//DUSP6//SYT2//SYT1//AR// GO:1901655 cellular response to ketone Biological process 6 86 466 17653 2.642928436 0.026191614 1 1.581837733 0.012875536 P2RY4//AR//RWDD1//EGFR//USP8//CDC5L// GO:1903727 positive regulation of phospholipid metabolic process Biological process 4 43 466 17653 3.523904581 0.026295196 1 1.580123589 0.008583691 HTR2B//ATG14//PIK3R4//ADGRF5// GO:0031348 negative regulation of defense response Biological process 10 187 466 17653 2.025774024 0.027015446 1 1.56838786 0.021459227 FCGR2B//RIOK3//ARRB2//ITCH//IFIT1//CALCRL//C1QTNF3//MMP26//SAA1//ADAR// GO:0000338 protein deneddylation Biological process 2 10 466 17653 7.57639485 0.027195002 1 1.565510902 0.004291845 COPS4//COPS2// GO:0003183 mitral valve morphogenesis Biological process 2 10 466 17653 7.57639485 0.027195002 1 1.565510902 0.004291845 BMPR2//ACVR1// GO:0018095 protein polyglutamylation Biological process 2 10 466 17653 7.57639485 0.027195002 1 1.565510902 0.004291845 TTLL6//TTLL7// GO:0030240 skeletal muscle thin filament assembly Biological process 2 10 466 17653 7.57639485 0.027195002 1 1.565510902 0.004291845 TTN//MYOM1// GO:0033327 Leydig cell differentiation Biological process 2 10 466 17653 7.57639485 0.027195002 1 1.565510902 0.004291845 AR//DHH// GO:0051409 response to nitrosative stress Biological process 2 10 466 17653 7.57639485 0.027195002 1 1.565510902 0.004291845 DUSP6//GCLM// GO:0061140 lung secretory cell differentiation Biological process 2 10 466 17653 7.57639485 0.027195002 1 1.565510902 0.004291845 HOXA5//ASCL1// GO:0070341 fat cell proliferation Biological process 2 10 466 17653 7.57639485 0.027195002 1 1.565510902 0.004291845 FTO//VSTM2A// GO:0070344 regulation of fat cell proliferation Biological process 2 10 466 17653 7.57639485 0.027195002 1 1.565510902 0.004291845 FTO//VSTM2A// GO:0070471 uterine smooth muscle contraction Biological process 2 10 466 17653 7.57639485 0.027195002 1 1.565510902 0.004291845 ADRA2B//ABAT// GO:1990253 cellular response to leucine starvation Biological process 2 10 466 17653 7.57639485 0.027195002 1 1.565510902 0.004291845 LARS//RRAGD// GO:2001214 positive regulation of vasculogenesis Biological process 2 10 466 17653 7.57639485 0.027195002 1 1.565510902 0.004291845 ADM//HIF1AN// GO:0060037 pharyngeal system development Biological process 3 25 466 17653 4.54583691 0.027323615 1 1.563461844 0.006437768 BMPR2//EYA1//ACVR1// GO:0006835 dicarboxylic acid transport Biological process 6 87 466 17653 2.612549948 0.027529349 1 1.560204066 0.012875536 SEPT2//PRAF2//SYT1//CCK//SLC46A1//ABAT// GO:0003007 heart morphogenesis Biological process 12 243 466 17653 1.870714778 0.028322961 1 1.547861339 0.025751073 AHI1//ACVR1//BMPR2//EYA1//GJA5//CHD7//SIRT6//ANKRD1//TTN//MYOM1//ADAMTS1//HTR2B// GO:0045776 negative regulation of blood pressure Biological process 4 44 466 17653 3.443815841 0.028340905 1 1.547586279 0.008583691 ARHGAP42//BMPR2//ABAT//GJA5// GO:0006940 regulation of smooth muscle contraction Biological process 5 65 466 17653 2.913998019 0.028398349 1 1.546706901 0.010729614 ADRA2B//ITGA2//CALCRL//ABAT//ARHGAP42// GO:0051047 positive regulation of secretion Biological process 17 388 466 17653 1.659777222 0.02926545 1 1.5336448 0.036480687 CCK//ABAT//GIPR//NR0B2//MPC2//GCG//ANO1//C2CD2L//SYT1//CACNA1H//ANKRD1//TTN//MYOM1//C1QTNF3//HTR2B//SAA1//EGFR// GO:0005996 monosaccharide metabolic process Biological process 13 273 466 17653 1.803903536 0.029840837 1 1.525188994 0.027896996 PFKFB4//FUCA2//PDHB//MAN2B1//RPIA//NCOA2//SIK3//CYB5R3//GCG//KAT2B//C1QTNF3//ABHD10//GCGR// GO:0010977 negative regulation of neuron projection development Biological process 8 138 466 17653 2.196056478 0.030120694 1 1.521135029 0.017167382 DCC//ULK2//SEMA4C//TRPC5//PTPRO//CTSZ//RAP1GAP2//ITM2C// GO:0009267 cellular response to starvation Biological process 8 139 466 17653 2.180257511 0.031254982 1 1.505080742 0.017167382 C12ORF66//LARS//ATG14//PIK3R4//RRAGD//USP33//STK26//BMPR2// GO:0050880 regulation of blood vessel size Biological process 8 139 466 17653 2.180257511 0.031254982 1 1.505080742 0.017167382 ADRA2B//EGFR//GJA5//HTR2B//ADM//BMPR2//ARHGAP42//GCLM// GO:0060840 artery development Biological process 6 90 466 17653 2.52546495 0.03181087 1 1.497424455 0.012875536 LOX//EYA1//CHD7//GJA5//PRRX1//BMPR2// GO:0035150 regulation of tube size Biological process 8 140 466 17653 2.164684243 0.032418187 1 1.489211272 0.017167382 ADRA2B//EGFR//GJA5//HTR2B//ADM//BMPR2//GCLM//ARHGAP42// GO:0003093 regulation of glomerular filtration Biological process 2 11 466 17653 6.887631682 0.032666162 1 1.485901894 0.004291845 GJA5//PTPRO// GO:0010820 positive regulation of T cell chemotaxis Biological process 2 11 466 17653 6.887631682 0.032666162 1 1.485901894 0.004291845 ADAM10//XCL1// GO:0010870 positive regulation of receptor biosynthetic process Biological process 2 11 466 17653 6.887631682 0.032666162 1 1.485901894 0.004291845 HNRNPK//HOXA5// GO:0015791 polyol transport Biological process 2 11 466 17653 6.887631682 0.032666162 1 1.485901894 0.004291845 AQP7//PGAP1// GO:0016322 neuron remodeling Biological process 2 11 466 17653 6.887631682 0.032666162 1 1.485901894 0.004291845 RND1//FARP2// GO:0038065 collagen-activated signaling pathway Biological process 2 11 466 17653 6.887631682 0.032666162 1 1.485901894 0.004291845 UBASH3B//ITGA2// GO:0045722 positive regulation of gluconeogenesis Biological process 2 11 466 17653 6.887631682 0.032666162 1 1.485901894 0.004291845 GCG//KAT2B// GO:0045945 positive regulation of transcription by RNA polymerase III Biological process 2 11 466 17653 6.887631682 0.032666162 1 1.485901894 0.004291845 BRF1//AR// GO:0090331 negative regulation of platelet aggregation Biological process 2 11 466 17653 6.887631682 0.032666162 1 1.485901894 0.004291845 ABAT//UBASH3B// GO:0007129 synapsis Biological process 4 46 466 17653 3.294084717 0.032709099 1 1.485331423 0.008583691 TEX12//SYCP1//BRIP1//CCDC36// GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway Biological process 4 46 466 17653 3.294084717 0.032709099 1 1.485331423 0.008583691 GIPR//ADM//HTR2B//ARRB2// GO:2000179 positive regulation of neural precursor cell proliferation Biological process 4 46 466 17653 3.294084717 0.032709099 1 1.485331423 0.008583691 CX3CR1//OTP//CTSZ//ASCL1// GO:0048738 cardiac muscle tissue development Biological process 11 221 466 17653 1.88552813 0.033170755 1 1.479244644 0.02360515 GJA5//CHD7//SIRT6//TTN//MYOM1//CACYBP//SOX6//ANKRD1//FGF9//ACVR1//ARRB2// GO:0070646 protein modification by small protein removal Biological process 14 306 466 17653 1.733162221 0.03322777 1 1.478498799 0.030042918 COPS4//COPS2//STAMBP//USP33//AR//ARRB2//YOD1//PSMB5//PSMD12//SUDS3//KAT2B//USP8//CDC25A//ITCH// GO:0030324 lung development Biological process 9 167 466 17653 2.041543522 0.033403483 1 1.476208244 0.019313305 HOXA5//BMPR2//CTSZ//FGF9//ASCL1//CELSR1//DHCR7//EGFR//LOX// GO:0031345 negative regulation of cell projection organization Biological process 9 167 466 17653 2.041543522 0.033403483 1 1.476208244 0.019313305 CTSZ//DCC//RAP1GAP2//PTPRO//ITM2C//TBC1D7//ULK2//SEMA4C//TRPC5// GO:0006359 regulation of transcription by RNA polymerase III Biological process 3 27 466 17653 4.20910825 0.03343568 1 1.475789839 0.006437768 BRF1//AR//ZNF345// GO:0032770 positive regulation of monooxygenase activity Biological process 3 27 466 17653 4.20910825 0.03343568 1 1.475789839 0.006437768 HTR2B//NPR3//NOS1AP// GO:1902692 regulation of neuroblast proliferation Biological process 3 27 466 17653 4.20910825 0.03343568 1 1.475789839 0.006437768 CX3CR1//OTP//SIX3// GO:0055008 cardiac muscle tissue morphogenesis Biological process 5 68 466 17653 2.785439283 0.033642759 1 1.473108392 0.010729614 CHD7//SIRT6//ANKRD1//TTN//MYOM1// GO:0070192 chromosome organization involved in meiotic cell cycle Biological process 5 68 466 17653 2.785439283 0.033642759 1 1.473108392 0.010729614 CCDC36//SYCP1//TEX12//NCAPD3//BRIP1// GO:0048589 developmental growth Biological process 24 609 466 17653 1.492885685 0.033729793 1 1.471986322 0.051502146 SIRT6//COL27A1//DHCR7//HOXA5//AR//GHR//FTO//PLAC8//CHD7//TRPC5//HLX//DCC//ULK2//BMPR2//SEMA4C//FGF9//DUSP6//UBE3A//PSAPL1//SYT2//SYT1//FLRT3//AURKA//ADM// GO:0010562 positive regulation of phosphorus metabolic process Biological process 40 1126 466 17653 1.345718446 0.034306438 1 1.464624372 0.08583691 GADD45A//STK26//EGFR//MAP3K15//KIDINS220//ADRA2B//DUSP6//GHR//SAA1//ATG14//FAM20A//CDK2AP1//HTR2B//ITGA2//GCG//TRPC5//BMPR2//ACVR1//MTMR9//ADM//PAK4//STK10//CCDC88A//TXN//SEMA4C//ARRB2//CNOT9//PIFO//LMTK2//AR//FGF9//JCAD//PIK3R4//PFKFB4//FCGR2B//CCK//C5AR2//DNAJC27//XCL1//ADGRF5// GO:0045937 positive regulation of phosphate metabolic process Biological process 40 1126 466 17653 1.345718446 0.034306438 1 1.464624372 0.08583691 GADD45A//STK26//EGFR//MAP3K15//KIDINS220//ADRA2B//DUSP6//GHR//SAA1//ATG14//FAM20A//CDK2AP1//HTR2B//ITGA2//GCG//TRPC5//BMPR2//ACVR1//MTMR9//ADM//PAK4//STK10//CCDC88A//TXN//SEMA4C//ARRB2//CNOT9//PIFO//LMTK2//AR//FGF9//JCAD//PIK3R4//PFKFB4//FCGR2B//CCK//C5AR2//DNAJC27//XCL1//ADGRF5// GO:0060537 muscle tissue development Biological process 17 396 466 17653 1.626246369 0.034533318 1 1.461761697 0.036480687 MYOM1//GJA5//CHD7//SIRT6//ZBTB18//HLX//EYA1//EYA2//ZNF689//ANKRD1//COPS2//TTN//CACYBP//SOX6//FGF9//ACVR1//ARRB2// GO:0015893 drug transport Biological process 10 195 466 17653 1.942665346 0.034583885 1 1.461126218 0.021459227 SEPT2//PRAF2//SYT1//NGB//SLC18A2//SLC46A1//SLC52A3//ABAT//SLC4A11//SLC25A15// GO:0050999 regulation of nitric-oxide synthase activity Biological process 4 47 466 17653 3.223997808 0.035032497 1 1.455528901 0.008583691 HTR2B//NPR3//NOS1AP//EGFR// GO:0010647 positive regulation of cell communication Biological process 58 1737 466 17653 1.26491336 0.036403609 1 1.438855564 0.124463519 GADD45A//STK26//EGFR//MAP3K15//KIDINS220//ADRA2B//DUSP6//GHR//SAA1//GJA5//NOS1AP//BMPR2//ACVR1//UBE3A//FGF9//RRAGD//ABAT//GIPR//NR0B2//ARRB2//SEMA4C//AR//GPR20//MPC2//GCG//ANO1//C2CD2L//CTH//HTR2B//GOLT1B//TRIM8//LMTK2//JCAD//ANKRD1//CNOT9//ASCL1//KAT2B//PRRX1//FCGR2B//GRIK2//SYT1//FAM110C//TXN//ITGA2//C1QTNF3//C5AR2//DNAJC27//XCL1//BMF//EDA//PSMB5//PSMD12//USP8//CX3CR1//LARS//RWDD1//LIMS2//ITM2C// GO:0032102 negative regulation of response to external stimulus Biological process 14 310 466 17653 1.710798837 0.036450308 1 1.438298797 0.030042918 FCGR2B//CCK//RIOK3//SEMA4C//ITCH//IFIT1//CALCRL//C1QTNF3//MMP26//SAA1//C5AR2//PTPRO//ABAT//UBASH3B// GO:0046636 negative regulation of alpha-beta T cell activation Biological process 3 28 466 17653 4.058782955 0.036735326 1 1.434916101 0.006437768 HLX//ITCH//XCL1// GO:0043412 macromolecule modification Biological process 133 4389 466 17653 1.147938614 0.03676745 1 1.434536493 0.285407725 GADD45A//CDC25A//DUSP6//EGFR//FGF9//MAP3K15//STK26//PSMB5//PSMD12//RASGRF2//KIDINS220//ADRA2B//GHR//SAA1//DUSP1//FBXO15//UBE3A//ITCH//COPS4//COPS2//NKTR//PPIL1//MRM2//ROPN1B//ATG14//CCDC88A//STAT2//ARRB2//FAM20A//CDK2AP1//TRAIP//KLHDC7A//KBTBD3//KBTBD12//NSMCE1//RNF149//FBXO43//PEX12//KLHL24//G2E3//CBLL1//TRIM8//RNF170//SPSB2//FTO//ADAR//AARS2//LOX//MAN2B1//TTLL2//ADAM10//ADCK5//LMTK2//FASTKD2//SIK3//PIK3R4//CDK17//RIPK4//AURKA//STK10//HASPIN//RIOK3//ACVR1//FLRT3//LRRC4C//NYX//UBASH3B//PTPN14//PTPRO//DUSP27//SIRT6//KAT2B//N6AMT1//HIF1AN//B3GNT5//DHDDS//WIPI2//GCG//TRPC5//BMPR2//PGAP1//GALNT11//KAT8//SUDS3//BRMS1L//EYA1//EYA2//STAMBP//USP33//AR//YOD1//USP8//NUPL2//HCCS//TTLL6//TTLL7//TTN//WEE1//GOLGA7B//CTH//NFS1//OPN5//DPY19L3//P3H2//PAK4//TBC1D7//TXN//PPP1R17//SET//SEMA4C//CNOT9//BMI1//TDRKH//TDRD1//HTR2B//JCAD//KCTD7//FUCA2//SERPIND1//MIA3//EVA1A//MUTYH//GRIK2//FCGR2B//ULK2//CCK//LTN1//C5AR2//DNAJC27//XCL1//ELK4//CMTR2//NOS1AP// GO:0044237 cellular metabolic process Biological process 308 10957 466 17653 1.064857905 0.037916642 1 1.421170128 0.660944206 ATG14//WIPI2//ULK2//SLC25A15//MCM4//CCDC88A//SET//BRIP1//CDC25A//GADD45A//CDT1//NFS1//CTH//ZBTB18//NCOA2//ELK4//FGF9//ZHX2//ZNF345//ANKRD1//AR//ASCL1//ZNF589//PEG3//PRRX1//SOX6//SUDS3//BMI1//TXN//ZNF202//NR0B2//BRMS1L//COPS2//DUSP6//EGFR//MAP3K15//STK26//PSMB5//PSMD12//RASGRF2//CASC3//NCBP2//KIDINS220//ADRA2B//GHR//SAA1//DUSP1//FBXO15//UBE3A//ITCH//LSM4//CNOT9//CNOT11//COPS4//MBNL2//MTREX//HNRNPK//NCBP2L//PPIL1//RAVER2//SNRNP25//FIP1L1//CDC5L//NKTR//NOP14//MRM2//TEX12//SYCP1//HMGN1//NSMCE1//GPC5//ITGB8//POP7//LMTK2//ROPN1B//STAT2//ARRB2//FAM20A//CDK2AP1//CTSZ//ADM//HTR2B//AHI1//RWDD1//KLF6//EGR4//HOXA5//PKNOX1//ZFAT//SIX3//BMPR2//TCEA1//CSRNP2//BRF1//TRAIP//KLHDC7A//KBTBD3//KBTBD12//RNF149//FBXO43//PEX12//KLHL24//G2E3//CBLL1//TRIM8//RNF170//SPSB2//GYG1//PFKFB4//IMPA2//ACOT12//ACAT1//PDHB//MRS2//GCGR//GIPR//AQP7//RPIA//NUPL2//ADGRF5//NME5//NT5C2//MCMBP//MGME1//EYA2//MUTYH//SMC1A//SIRT6//EYA1//FTO//CCDC36//ZBTB33//FSBP//YAF2//ZNF689//ZNF813//ZNF491//ZNF578//ZNF600//ZNF780B//ZNF507//OTP//ZNF707//LIN9//SAP30BP//HLX//ZNF888//ARGFX//CHD7//HIF1AN//NCOA5//PTPN14//GPBP1//ZFP69B//UBP1//ZNF19//ZNF33A//ZNF426//TFEB//ASXL3//KAT8//TBPL2//ELL2//ZNF45//DIS3//RIOK3//KAT2B//CMTR2//ADAR//ELAVL4//RBM3//SRSF8//AARS2//RNASEH1//FARSB//MRPL3//MRPL10//ABCF1//EIF1B//EIF3C//N6AMT1//MTRF1L//LARS//NARS2//LRRC47//LOX//MAN2B1//TTLL2//ADAM10//ADCK5//FASTKD2//SIK3//PIK3R4//CDK17//RIPK4//AURKA//STK10//HASPIN//ACVR1//FLRT3//LRRC4C//NYX//UBASH3B//PTPRO//DUSP27//B3GNT5//DHDDS//PGAP1//CLPP//USP33//ZSWIM9//USP8//ODC1//GCLM//GLYAT//HAL//PHOSPHO1//PI4KB//MTMR12//MTMR9//PSAPL1//KDSR//GALC//OSBPL2//HSD17B11//CA3//NUDT12//SLC52A3//ABCD4//UROS//SLC17A4//CYB5R3//MARC1//DEPP1//EVA1A//CCK//NPR3//GALNT11//USB1//ABAT//RRAGD//BMF//ITGA2//GCG//TRPC5//PPP1R17//ARFGEF3//SERPIND1//YOD1//EXOC4//XCL1//STAMBP//HCCS//TTLL6//TTLL7//TTN//WEE1//GOLGA7B//OPN5//DPY19L3//CACYBP//ELOVL7//ABHD10//UPB1//P3H2//GMDS//PAK4//SPTSSA//HACD2//HS3ST4//TBC1D7//CALCRL//CACNA1H//SEMA4C//PIFO//RNF113B//TDRKH//TDRD1//PRDX6//ITM2C//LTN1//JCAD//KCTD7//FUCA2//MIA3//TTC37//GGA2//TGFBI//NOS1AP//C1QTNF3//DDN//PLAC8//GRIK2//FCGR2B//DGKB//SLC46A1//PACSIN3//EDA//TRAPPC9//MPC2//MRPS10//C5AR2//DNAJC27//TUSC2//ZC3H12B//LILRB4//SLC18A2//SHQ1// GO:0030323 respiratory tube development Biological process 9 171 466 17653 1.993788118 0.037971419 1 1.420543176 0.019313305 DHCR7//EGFR//LOX//HOXA5//BMPR2//CTSZ//FGF9//ASCL1//CELSR1// GO:0010819 regulation of T cell chemotaxis Biological process 2 12 466 17653 6.313662375 0.038526151 1 1.414244378 0.004291845 ADAM10//XCL1// GO:0014866 skeletal myofibril assembly Biological process 2 12 466 17653 6.313662375 0.038526151 1 1.414244378 0.004291845 TTN//MYOM1// GO:0030497 fatty acid elongation Biological process 2 12 466 17653 6.313662375 0.038526151 1 1.414244378 0.004291845 ELOVL7//HACD2// GO:0043201 response to leucine Biological process 2 12 466 17653 6.313662375 0.038526151 1 1.414244378 0.004291845 LARS//RRAGD// GO:0048505 regulation of timing of cell differentiation Biological process 2 12 466 17653 6.313662375 0.038526151 1 1.414244378 0.004291845 ASCL1//FGF9// GO:0060742 epithelial cell differentiation involved in prostate gland development Biological process 2 12 466 17653 6.313662375 0.038526151 1 1.414244378 0.004291845 AR//PSAPL1// GO:0072520 seminiferous tubule development Biological process 2 12 466 17653 6.313662375 0.038526151 1 1.414244378 0.004291845 AR//BRIP1// GO:0098789 pre-mRNA cleavage required for polyadenylation Biological process 2 12 466 17653 6.313662375 0.038526151 1 1.414244378 0.004291845 NCBP2//FIP1L1// GO:1901678 iron coordination entity transport Biological process 2 12 466 17653 6.313662375 0.038526151 1 1.414244378 0.004291845 SLC46A1//FLVCR2// GO:0048598 embryonic morphogenesis Biological process 23 586 466 17653 1.486835167 0.038556064 1 1.413907302 0.049356223 ACVR1//DUSP1//BMPR2//ADM//SEMA4C//RALA//CELSR1//AHI1//FLRT3//SIX3//EYA1//EYA2//FGF9//GJA5//PRRX1//CHD7//DUSP6//ITGA2//EXOC4//HLX//HOXA5//AR//HTR2B// GO:0090114 COPII-coated vesicle budding Biological process 5 71 466 17653 2.667744665 0.039451325 1 1.403938402 0.010729614 SEC23IP//CTSZ//TRAPPC9//SEC24C//MIA3// GO:0072359 circulatory system development Biological process 39 1105 466 17653 1.337010856 0.039514548 1 1.403242977 0.083690987 CALCRL//FGF9//GJA5//PKNOX1//TGFBI//UBP1//FMNL3//DHCR7//LOX//ACVR1//ADM//PTPN14//BMPR2//AHI1//HTR2B//CHD7//EYA1//SIRT6//FLRT3//CACYBP//KAT2B//CX3CR1//HOXA5//SEMA6A//PAK4//ITGB8//TTN//MYOM1//PRRX1//SOX6//ANKRD1//ADAMTS1//DUSP6//GALNT11//JCAD//CTH//EGFR//ARRB2//HIF1AN// GO:0010906 regulation of glucose metabolic process Biological process 6 95 466 17653 2.392545742 0.039867178 1 1.399384501 0.012875536 GCG//KAT2B//C1QTNF3//GCGR//NCOA2//SIK3// GO:0010675 regulation of cellular carbohydrate metabolic process Biological process 7 120 466 17653 2.209781831 0.03990328 1 1.398991406 0.015021459 NCOA2//SIK3//GCG//KAT2B//C1QTNF3//SIRT6//GCGR// GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway Biological process 3 29 466 17653 3.918824922 0.040195443 1 1.395823178 0.006437768 DGKB//HTR2B//CCK// GO:0051955 regulation of amino acid transport Biological process 3 29 466 17653 3.918824922 0.040195443 1 1.395823178 0.006437768 SEPT2//CCK//ABAT// GO:0060441 epithelial tube branching involved in lung morphogenesis Biological process 3 29 466 17653 3.918824922 0.040195443 1 1.395823178 0.006437768 CELSR1//CTSZ//HOXA5// GO:1903432 regulation of TORC1 signaling Biological process 3 29 466 17653 3.918824922 0.040195443 1 1.395823178 0.006437768 C12ORF66//LARS//RRAGD// GO:0042325 regulation of phosphorylation Biological process 52 1544 466 17653 1.275817786 0.040617079 1 1.391291313 0.111587983 GADD45A//CDC25A//STK26//EGFR//MAP3K15//KIDINS220//ADRA2B//DUSP6//GHR//SAA1//DUSP1//ROPN1B//ATG14//CCDC88A//STAT2//ARRB2//FAM20A//CDK2AP1//NUPL2//FLRT3//LRRC4C//NYX//UBASH3B//GCG//TRPC5//BMPR2//ACVR1//PAK4//STK10//TXN//SEMA4C//CNOT9//PIFO//LMTK2//AR//HTR2B//RNF149//FGF9//JCAD//PIK3R4//ADAR//KAT2B//SIRT6//PFKFB4//TTN//GRIK2//ITCH//FCGR2B//CCK//C5AR2//DNAJC27//XCL1// GO:0048844 artery morphogenesis Biological process 5 72 466 17653 2.630692656 0.04151471 1 1.381797989 0.010729614 EYA1//CHD7//BMPR2//GJA5//PRRX1// GO:0008593 regulation of Notch signaling pathway Biological process 6 96 466 17653 2.367623391 0.041619853 1 1.380699462 0.012875536 EGFR//HIF1AN//DLK1//ASCL1//KAT2B//GALNT11// GO:0006109 regulation of carbohydrate metabolic process Biological process 9 174 466 17653 1.959412461 0.041664857 1 1.380230106 0.019313305 NUPL2//NCOA2//SIK3//GCG//KAT2B//C1QTNF3//SIRT6//PFKFB4//GCGR// GO:1903530 regulation of secretion by cell Biological process 26 687 466 17653 1.433670059 0.042358388 1 1.373060575 0.055793991 GCG//GIPR//ADRA2B//CCK//SYT1//RALA//SYT2//C2CD4A//SYT6//ABAT//NR0B2//MPC2//ANO1//C2CD2L//FCGR2B//CACNA1H//SAA1//ANKRD1//TTN//MYOM1//C1QTNF3//HTR2B//CHD7//GJA5//C5AR2//EGFR// GO:0045933 positive regulation of muscle contraction Biological process 4 50 466 17653 3.03055794 0.04256302 1 1.370967567 0.008583691 ITGA2//ADRA2B//ABAT//NOS1AP// GO:0001913 T cell mediated cytotoxicity Biological process 3 30 466 17653 3.788197425 0.043814231 1 1.358384804 0.006437768 XCL1//FCGR2B//RAET1E// GO:0071108 protein K48-linked deubiquitination Biological process 3 30 466 17653 3.788197425 0.043814231 1 1.358384804 0.006437768 USP33//YOD1//USP8// GO:0021781 glial cell fate commitment Biological process 2 13 466 17653 5.827996038 0.044750723 1 1.349199942 0.004291845 ASCL1//SOX6// GO:0033604 negative regulation of catecholamine secretion Biological process 2 13 466 17653 5.827996038 0.044750723 1 1.349199942 0.004291845 ADRA2B//ABAT// GO:0042659 regulation of cell fate specification Biological process 2 13 466 17653 5.827996038 0.044750723 1 1.349199942 0.004291845 DUSP6//AR// GO:0042761 very long-chain fatty acid biosynthetic process Biological process 2 13 466 17653 5.827996038 0.044750723 1 1.349199942 0.004291845 HACD2//ELOVL7// GO:0048739 cardiac muscle fiber development Biological process 2 13 466 17653 5.827996038 0.044750723 1 1.349199942 0.004291845 TTN//MYOM1// GO:0060081 membrane hyperpolarization Biological process 2 13 466 17653 5.827996038 0.044750723 1 1.349199942 0.004291845 TRPC5//KCTD7// GO:0060601 lateral sprouting from an epithelium Biological process 2 13 466 17653 5.827996038 0.044750723 1 1.349199942 0.004291845 CELSR1//AR// GO:0071688 striated muscle myosin thick filament assembly Biological process 2 13 466 17653 5.827996038 0.044750723 1 1.349199942 0.004291845 TTN//MYOM1// GO:0090110 cargo loading into COPII-coated vesicle Biological process 2 13 466 17653 5.827996038 0.044750723 1 1.349199942 0.004291845 MIA3//SEC24C// GO:0090335 regulation of brown fat cell differentiation Biological process 2 13 466 17653 5.827996038 0.044750723 1 1.349199942 0.004291845 VSTM2A//FTO// GO:1903725 regulation of phospholipid metabolic process Biological process 5 74 466 17653 2.559592855 0.045833965 1 1.338812573 0.010729614 HTR2B//ATG14//PIK3R4//MTMR9//ADGRF5// GO:0044262 cellular carbohydrate metabolic process Biological process 12 262 466 17653 1.735052256 0.046039401 1 1.336870336 0.025751073 GYG1//IMPA2//NCOA2//SIK3//ABHD10//B3GNT5//GCG//KAT2B//C1QTNF3//SIRT6//PFKFB4//GCGR// GO:0003209 cardiac atrium morphogenesis Biological process 3 31 466 17653 3.665997508 0.047589639 1 1.322487594 0.006437768 ACVR1//GJA5//BMPR2// GO:0046949 fatty-acyl-CoA biosynthetic process Biological process 3 31 466 17653 3.665997508 0.047589639 1 1.322487594 0.006437768 HACD2//ELOVL7//ACAT1// GO:0036465 synaptic vesicle recycling Biological process 4 52 466 17653 2.913998019 0.048050736 1 1.318299959 0.008583691 SYT2//C2CD4A//SYT1//STON2// GO:0006793 phosphorus metabolic process Biological process 103 3352 466 17653 1.164034412 0.048648294 1 1.312932388 0.221030043 GADD45A//CDC25A//DUSP6//EGFR//FGF9//MAP3K15//STK26//PSMB5//PSMD12//RASGRF2//KIDINS220//ADRA2B//GHR//SAA1//DUSP1//ROPN1B//ATG14//CCDC88A//STAT2//ARRB2//FAM20A//CDK2AP1//PFKFB4//ACOT12//ACAT1//PDHB//RPIA//NUPL2//NME5//ADM//HTR2B//NT5C2//ADAM10//ADCK5//LMTK2//FASTKD2//SIK3//PIK3R4//CDK17//RIPK4//AURKA//STK10//HASPIN//RIOK3//ACVR1//FLRT3//LRRC4C//NYX//UBASH3B//PTPN14//PTPRO//DUSP27//DHDDS//PGAP1//GLYAT//PHOSPHO1//PI4KB//MTMR12//MTMR9//NUDT12//NFS1//SLC17A4//IMPA2//NPR3//ITGA2//GCG//TRPC5//BMPR2//PPP1R17//ARFGEF3//CSRNP2//CA3//EYA1//EYA2//TTN//WEE1//PAK4//TXN//SET//SEMA4C//CNOT9//PIFO//HACD2//ELOVL7//AR//GMDS//RNF149//JCAD//ADAR//KAT2B//SIRT6//GRIK2//ITCH//FCGR2B//PRDX6//ULK2//DGKB//CCK//MPC2//C5AR2//DNAJC27//XCL1//ADGRF5// GO:0000070 mitotic sister chromatid segregation Biological process 8 152 466 17653 1.993788118 0.048726402 1 1.312235654 0.017167382 PRC1//SMC1A//HASPIN//NCAPD3//NCAPG//TTN//CDT1//DUSP1// GO:1990138 neuron projection extension Biological process 8 152 466 17653 1.993788118 0.048726402 1 1.312235654 0.017167382 TRPC5//ULK2//BMPR2//SEMA4C//SYT2//SYT1//FLRT3//AURKA// GO:0044424 intracellular part Cellular component 407 14395 492 18698 1.074515767 9.84E-04 0.845090339 3.007090027 0.827235772 FBXO15//BMI1//CBLL1//DIS3//MTREX//RGS11//PSMB5//PSMD12//UBE3A//FARSB//MBNL2//ADAM10//CALCRL//POP7//PAK4//ADAR//NCOA2//COLEC10//DEPP1//SEC23IP//XPOT//SLC46A1//KRT74//MSI2//RBM45//ADM//NUDCD2//ZNF578//CTH//ROPN1B//FGD5//KCTD7//DGKB//GADD45A//CYB5R3//DUSP1//DUSP6//EGFR//CCDC125//EYA1//FGF9//LMTK2//NCBP2//KLHDC10//USP33//DDN//DNAJC9//SIK3//HEBP2//FLRT3//RNASEH1//GABRB1//WDR72//CHRDL2//ANKRD1//GJB3//RND1//GMDS//NKIRAS2//N6AMT1//PACSIN3//HMGN1//HMGN2//HNRNPK//HTR2B//ANKRD34B//IFIT1//IMPA2//AQP7//AR//TBPL2//ARRB2//SEPT2//ODC1//HSD17B11//LUZP4//CDK17//RWDD1//LARS//SIRT6//STK26//PI4KB//PKNOX1//RIPK4//MTMR12//KLHL24//RALGPS2//ANO1//SHQ1//RIC8B//RAVER2//YOD1//HIF1AN//ARHGEF40//CCDC88A//CMTR2//UNC45A//TDRD1//MTUS1//LRRC4C//PTPN14//RRAGD//RBM3//EXOC4//NYX//RP2//NCAPG//SET//BMPR2//MTMR9//SNTB1//STK10//TRPC5//TUFT1//TXN//WEE1//PSAPL1//ZNF185//C1ORF116//TFEB//ARHGAP28//LRRC8E//CDT1//ITCH//HASPIN//BRIP1//NR0B2//UBASH3B//BCAS1//USP8//FMNL3//DUSP27//CYTH2//CYTH1//COPS2//PRDX6//TTC37//FARP2//CDC5L//NCBP2L//CLPP//TRAPPC9//CNOT11//CNOT9//ABAT//DPY19L3//SLC25A15//MRPL3//SFXN2//MRPL10//HCCS//ACAT1//MCUB//MRPS10//MRS2//MARC1//KANSL1L//KAT8//DHCR7//BMF//KLF6//CTSZ//DIAPH2//EDA//NSMCE1//RPIA//PIK3R4//MIA3//G2E3//GPBP1//EVA1A//WIPI2//ULK2//KIF19//ATG14//GLYAT//TDRKH//TUSC2//EYA2//FASTKD2//BCLAF3//GALC//MPC2//BLOC1S2//MRM2//MUTYH//NKTR//DNAJC27//PDHB//MTRF1L//NIPSNAP3B//ABHD10//AARS2//NGB//UROS//NARS2//NFS1//OXNAD1//MGME1//NOS1AP//GLB1L//ZBTB33//YAF2//FAM13A//STAMBP//SRSF8//NUPL2//SEC63//CNTROB//ACOT12//SYT6//PHOSPHO1//DCC//DSG3//ELK4//CASC3//ZHX2//NT5C2//ABCF1//RAP1GAP2//FAM120A//LSM4//PNISR//LTN1//GHR//CACYBP//DENND2A//GCLM//TMEM97//TTLL6//GYG1//HAL//KRTAP8-1//CEP83//COPS4//TBC1D7//PDE1C//UPB1//RAPGEF6//PFKFB4//PRRX1//LZTFL1//AHI1//LIMS2//KIDINS220//ZFAT//RASGRF2//SUDS3//STAT2//AURKA//SYT1//TTN//UBP1//CA3//SNRNP25//TTLL7//MCMBP//DENND2D//CDK2AP1//TRIM8//SMC1A//NUDT12//PARD6B//SPSB2//STON2//EIF3C//RIOK3//PRC1//SEC24C//OSBPL2//CDC25A//HACD2//KDSR//GOLT1B//TXNDC11//GPR85//FAM20A//P3H2//ATL2//DHDDS//ELOVL7//PGAP1//B3GNT5//GGA2//GALNT11//ITM2C//SAA1//LRRC47//PIFO//ADGRF5//RGS17//ANP32E//ADAMTS1//TRAIP//CX3CR1//FAT1//ITGA2//JCAD//MS4A3//FUCA2//GCG//SERPIND1//COL14A1//COL27A1//GPC5//KAT2B//KLHDC7A//KBTBD3//KBTBD12//PEG3//FAM110C//CD302//ASCL1//MAN2B1//PLAC8//PXT1//PEX12//ABCD4//FSBP//ZBTB18//ZNF689//ZNF813//ZNF491//C2CD4A//ZNF600//ZNF780B//EGR4//ZNF507//TSPYL4//OTP//ZNF345//NAP1L5//ZNF707//FBXO43//SAP30BP//HLX//HOXA5//ZSWIM9//ZNF888//LYSMD1//VWA5A//LOX//MCM4//ARGFX//ZNF589//PPIL1//SOX6//CHD7//SENP7//PLEKHG1//NCOA5//C11ORF1//SIX3//ZFP69B//TCEA1//ZNF19//ZNF33A//ZNF45//ZNF202//FTO//ZNF426//TMEM53//USB1//ASXL3//CSRNP2//NOP14//GCGR//BLOC1S5//RALA//SCAMP1//ATP1B3//TGFBI//ZNF330//CCDC68//FRMPD3//CORO2A//SYCP1//NCAPD3//TEX12//BRMS1L//CCDC36//PPP1R17//ELL2//LIN9//BRF1//SCAF4//FIP1L1//CELSR1//RNF113B//R3HCC1//MYOM1//WDR5B//CNGA4//GOLGA7B//HS3ST4//SPTSSA//PAFAH2//SLC28A3//RNF170//C2CD2L//ARFGEF3//PRAF2//GRIK2//C12ORF66//SLC18A2//SYT2//SEMA4C// GO:0005622 intracellular Cellular component 411 14673 492 18698 1.064517872 2.67E-03 0.913699168 2.573557431 0.835365854 KANSL1L//KAT8//KAT2B//BRF1//ADAM10//SEC23IP//CNGA4//CTSZ//EGFR//MIA3//GOLGA7B//GOLT1B//STK26//PI4KB//GALNT11//TRAPPC9//B3GNT5//CYTH2//CYTH1//SEC24C//HS3ST4//SEPT2//EXOC4//FBXO15//BMI1//CBLL1//DIS3//MTREX//ZBTB18//CCDC36//TTN//SMC1A//NCAPG//RGS11//WIPI2//ULK2//ATG14//PSMB5//PSMD12//UBE3A//ZNF330//SYCP1//CDT1//NUDCD2//NCAPD3//AURKA//NSMCE1//MCM4//HMGN1//HMGN2//HNRNPK//AR//MCMBP//ASXL3//TEX12//ANP32E//FAM110C//PRC1//BLOC1S2//LSM4//CNOT9//KLF6//ANKRD1//BMF//KRTAP8-1//KIF19//PIK3R4//CALCRL//FUCA2//GALC//TMEM97//LARS//RRAGD//PSAPL1//ITM2C//GLYAT//TDRKH//DEPP1//MRPL3//TUSC2//MRPL10//CYB5R3//ABAT//EYA2//FASTKD2//HEBP2//BCLAF3//MPC2//MRM2//HCCS//ACAT1//MUTYH//NKTR//DNAJC27//PDHB//MTRF1L//MCUB//MRPS10//NIPSNAP3B//ABHD10//MRS2//AARS2//MTUS1//NGB//MARC1//TXN//UROS//NARS2//CLPP//NFS1//OXNAD1//MGME1//PRDX6//NOS1AP//GLB1L//ZBTB33//FARSB//YAF2//FAM13A//STAMBP//SRSF8//NUPL2//SEC63//XPOT//CNTROB//KRT74//ACOT12//SYT6//CTH//KCTD7//PHOSPHO1//DCC//DHCR7//DIAPH2//DSG3//DUSP6//ELK4//CASC3//LMTK2//ZHX2//NCBP2//RPIA//NT5C2//ABCF1//USP33//RAP1GAP2//FAM120A//DNAJC9//FLRT3//PNISR//LTN1//GHR//CACYBP//DENND2A//RND1//GCLM//GMDS//TTLL6//N6AMT1//PACSIN3//GYG1//HAL//IFIT1//IMPA2//ARRB2//ODC1//CEP83//COPS4//HSD17B11//TBC1D7//PDE1C//UPB1//RAPGEF6//PFKFB4//PRRX1//MTMR12//LZTFL1//AHI1//SHQ1//RIC8B//YOD1//CNOT11//G2E3//HIF1AN//LIMS2//CCDC88A//UNC45A//KIDINS220//ZFAT//RASGRF2//SET//SUDS3//GPBP1//MTMR9//STAT2//SYT1//UBP1//CA3//C1ORF116//SNRNP25//TTLL7//ARHGAP28//DENND2D//CDK2AP1//TRIM8//NUDT12//ITCH//PARD6B//SPSB2//STON2//EIF3C//RIOK3//USP8//FMNL3//COPS2//TTC37//FARP2//OSBPL2//CDC25A//PXT1//PEX12//ABCD4//FSBP//MBNL2//POP7//ADAR//NCOA2//ZNF689//ZNF813//ZNF491//PIFO//RBM45//C2CD4A//ZNF578//CX3CR1//ZNF600//ZNF780B//GADD45A//DUSP1//EGR4//EYA1//FAT1//ZNF507//DDN//TSPYL4//OTP//RNASEH1//ZNF345//RGS17//NAP1L5//ZNF707//FBXO43//SAP30BP//HLX//HOXA5//ANKRD34B//ITGA2//ZSWIM9//TBPL2//ZNF888//LYSMD1//VWA5A//LOX//ASCL1//ARGFX//LUZP4//CDK17//ZNF589//SIRT6//PPIL1//PEG3//PKNOX1//RAVER2//SOX6//CHD7//CMTR2//SENP7//PLEKHG1//NCOA5//PTPN14//RBM3//C11ORF1//SIX3//ZFP69B//TCEA1//WEE1//ZNF19//ZNF33A//ZNF45//ZNF202//FTO//ZNF426//TFEB//TMEM53//USB1//CSRNP2//HASPIN//BRIP1//NR0B2//UBASH3B//NOP14//CDC5L//GABRB1//DPY19L3//PAK4//COLEC10//SLC46A1//MSI2//ADM//ROPN1B//FGD5//DGKB//CCDC125//FGF9//KLHDC10//SIK3//WDR72//CHRDL2//GJB3//NKIRAS2//HTR2B//AQP7//RWDD1//RIPK4//KLHL24//RALGPS2//ANO1//ARHGEF40//TDRD1//LRRC4C//NYX//RP2//BMPR2//SNTB1//STK10//TRPC5//TUFT1//ZNF185//LRRC8E//BCAS1//DUSP27//PPP1R17//ELL2//LIN9//SCAF4//FIP1L1//CELSR1//RNF113B//TRAIP//SLC25A15//SFXN2//C12ORF66//EVA1A//GCGR//MAN2B1//HACD2//KDSR//TXNDC11//GPR85//FAM20A//P3H2//ATL2//DHDDS//ELOVL7//PGAP1//GCG//SERPIND1//COL14A1//COL27A1//SPTSSA//EDA//PAFAH2//SLC28A3//RNF170//C2CD2L//GGA2//GPC5//TGFBI//SCAMP1//BLOC1S5//ARFGEF3//FRMPD3//RALA//CCDC68//NCBP2L//MYOM1//SAA1//CD302//SLC18A2//LRRC47//PRAF2//CORO2A//SYT2//SEMA4C//ADGRF5//ADAMTS1//KLHDC7A//KBTBD3//KBTBD12//GRIK2//R3HCC1//PLAC8//MS4A3//WDR5B//ATP1B3//JCAD//BRMS1L//ADRA2B//MAP3K15//NPR3//NME5// GO:0005737 cytoplasm Cellular component 333 11544 492 18698 1.096271107 0.003191033 0.913699168 2.49606868 0.676829268 RND1//SEPT2//RIC8B//FAM110C//ITCH//PARD6B//CD302//CTSZ//GRIK2//BLOC1S2//BLOC1S5//P3H2//TDRD1//KIF19//ATG14//PIK3R4//ADAM10//SEC23IP//CNGA4//EGFR//MIA3//GOLGA7B//GOLT1B//STK26//PI4KB//GALNT11//TRAPPC9//B3GNT5//CYTH2//CYTH1//SEC24C//HS3ST4//EXOC4//DIS3//WIPI2//ULK2//LSM4//CNOT9//BMF//CALCRL//FUCA2//GALC//TMEM97//LARS//RRAGD//PSAPL1//ITM2C//GLYAT//TDRKH//DEPP1//MRPL3//TUSC2//MRPL10//CYB5R3//ABAT//EYA2//FASTKD2//HEBP2//BCLAF3//MPC2//MRM2//HCCS//ACAT1//MUTYH//NKTR//DNAJC27//PDHB//MTRF1L//MCUB//MRPS10//NIPSNAP3B//ABHD10//MRS2//AARS2//MTUS1//NGB//MARC1//TXN//UROS//NARS2//CLPP//NFS1//OXNAD1//MGME1//PRDX6//NOS1AP//GLB1L//ZBTB33//FARSB//YAF2//FAM13A//STAMBP//SRSF8//NUPL2//SEC63//XPOT//CNTROB//KRT74//KLF6//ACOT12//SYT6//CTH//KCTD7//PHOSPHO1//DCC//DHCR7//DIAPH2//DSG3//DUSP6//ELK4//FBXO15//CASC3//LMTK2//ZHX2//NCBP2//RPIA//NT5C2//ABCF1//USP33//RAP1GAP2//FAM120A//DNAJC9//FLRT3//PNISR//LTN1//GHR//ANKRD1//CACYBP//DENND2A//GCLM//GMDS//TTLL6//N6AMT1//PACSIN3//GYG1//HAL//KRTAP8-1//IFIT1//IMPA2//AR//ARRB2//ODC1//CEP83//COPS4//HSD17B11//TBC1D7//PDE1C//UPB1//RAPGEF6//PFKFB4//PRRX1//MTMR12//LZTFL1//AHI1//SHQ1//YOD1//CNOT11//G2E3//HIF1AN//LIMS2//CCDC88A//UNC45A//PSMB5//PSMD12//KIDINS220//ZFAT//RASGRF2//NCAPG//SET//SUDS3//BMI1//GPBP1//MTMR9//STAT2//AURKA//SYT1//TTN//UBE3A//UBP1//CA3//C1ORF116//SNRNP25//TTLL7//ARHGAP28//CBLL1//MCMBP//DENND2D//CDK2AP1//TRIM8//CDT1//SMC1A//NUDT12//SPSB2//STON2//EIF3C//RIOK3//PRC1//USP8//FMNL3//COPS2//TTC37//FARP2//OSBPL2//CDC25A//PXT1//PEX12//ABCD4//SLC25A15//SFXN2//C12ORF66//EVA1A//WDR72//GCGR//FGD5//MAN2B1//PEG3//HACD2//KDSR//TXNDC11//GPR85//FAM20A//ATL2//DHDDS//ELOVL7//PGAP1//GCG//SERPIND1//COL14A1//COL27A1//SPTSSA//EDA//DDN//PAFAH2//SLC28A3//LRRC8E//RNF170//C2CD2L//PAK4//COLEC10//GGA2//RP2//GPC5//PIFO//TGFBI//SCAMP1//ARFGEF3//FRMPD3//RALA//CCDC68//MYOM1//SAA1//SLC18A2//LRRC47//PRAF2//RBM3//DUSP27//SYT2//C2CD4A//SEMA4C//ADGRF5//RGS17//ANP32E//ADAMTS1//KAT2B//PLAC8//STK10//MS4A3//ATP1B3//TRAIP//CX3CR1//FAT1//ITGA2//JCAD//CDC5L//MBNL2//POP7//ADAR//NCOA2//SLC46A1//MSI2//RBM45//ADM//NUDCD2//ZNF578//ROPN1B//DGKB//GADD45A//DUSP1//CCDC125//EYA1//FGF9//KLHDC10//SIK3//RNASEH1//GABRB1//CHRDL2//GJB3//NKIRAS2//HMGN1//HMGN2//HNRNPK//HTR2B//ANKRD34B//AQP7//TBPL2//LUZP4//CDK17//RWDD1//SIRT6//PKNOX1//RIPK4//KLHL24//RALGPS2//ANO1//RAVER2//ARHGEF40//CMTR2//LRRC4C//PTPN14//NYX//BMPR2//SNTB1//TRPC5//TUFT1//WEE1//ZNF185//TFEB//HASPIN//BRIP1//NR0B2//UBASH3B//BCAS1//RGS11// GO:0034045 phagophore assembly site membrane Cellular component 3 16 492 18698 7.125762195 0.007855023 1 2.10485256 0.006097561 ATG14//WIPI2//ULK2// GO:0005829 cytosol Cellular component 155 5022 492 18698 1.17296497 0.011451393 1 1.941141669 0.31504065 CYB5R3//BLOC1S2//BLOC1S5//ZBTB33//FARSB//YAF2//FAM13A//STAMBP//SRSF8//NUPL2//SEC23IP//SEC63//XPOT//CNTROB//KRT74//KLF6//ACOT12//SYT6//CTH//KCTD7//PHOSPHO1//DCC//DHCR7//DIAPH2//DSG3//DUSP6//ELK4//FBXO15//EYA2//CASC3//LMTK2//ATG14//ZHX2//DIS3//NCBP2//RPIA//NT5C2//ABCF1//USP33//RAP1GAP2//FAM120A//DNAJC9//FLRT3//LSM4//PNISR//LTN1//WIPI2//GHR//ANKRD1//CACYBP//DENND2A//RND1//GCLM//TMEM97//GMDS//TTLL6//N6AMT1//PACSIN3//GYG1//HAL//PIK3R4//KRTAP8-1//IFIT1//IMPA2//AR//ACAT1//ARRB2//NKTR//ODC1//CEP83//COPS4//HSD17B11//TBC1D7//PDE1C//LARS//UPB1//RAPGEF6//STK26//PFKFB4//PI4KB//PRRX1//MTMR12//LZTFL1//AHI1//SHQ1//RIC8B//ABHD10//YOD1//CNOT11//G2E3//HIF1AN//LIMS2//CCDC88A//UNC45A//PSMB5//PSMD12//KIDINS220//ZFAT//NGB//RRAGD//RASGRF2//EXOC4//NCAPG//SET//SUDS3//BMI1//GPBP1//MTMR9//STAT2//AURKA//SYT1//TTN//TXN//UBE3A//UBP1//UROS//CA3//PSAPL1//C1ORF116//SNRNP25//NARS2//TTLL7//ARHGAP28//CBLL1//MCMBP//DENND2D//CDK2AP1//TRIM8//CDT1//SMC1A//NUDT12//TRAPPC9//ITCH//PARD6B//SPSB2//STON2//EIF3C//RIOK3//BMF//NFS1//PRC1//USP8//FMNL3//CNOT9//CYTH2//CYTH1//COPS2//PRDX6//SEC24C//TTC37//ULK2//NOS1AP//FARP2//OSBPL2//CDC25A// GO:0000793 condensed chromosome Cellular component 12 217 492 18698 2.101607283 0.012605021 1 1.899456437 0.024390244 CCDC36//TTN//SMC1A//NCAPD3//NCAPG//NSMCE1//AURKA//SYCP1//NUDCD2//SEPT2//CDT1//TEX12// GO:0000794 condensed nuclear chromosome Cellular component 7 96 492 18698 2.771129743 0.013373603 1 1.873751565 0.014227642 AURKA//NCAPD3//SYCP1//TEX12//CCDC36//TTN//SMC1A// GO:0000775 chromosome, centromeric region Cellular component 11 194 492 18698 2.154869667 0.013932067 1 1.855984453 0.022357724 CDT1//SMC1A//KAT8//KAT2B//NCAPD3//NCAPG//AURKA//NUDCD2//SEPT2//ZNF330//SYCP1// GO:0030672 synaptic vesicle membrane Cellular component 7 98 492 18698 2.714576074 0.014850288 1 1.82826511 0.014227642 SYT1//SYT2//C2CD4A//SYT6//SEMA4C//SLC18A2//SCAMP1// GO:0099501 exocytic vesicle membrane Cellular component 7 98 492 18698 2.714576074 0.014850288 1 1.82826511 0.014227642 SYT2//C2CD4A//SYT6//SEMA4C//SLC18A2//SYT1//SCAMP1// GO:0045177 apical part of cell Cellular component 17 366 492 18698 1.765216136 0.017428678 1 1.758735563 0.034552846 SLC17A4//SLC46A1//SLC52A3//EGFR//P2RY4//RAPGEF6//STK26//ANO1//PTPRO//BMPR2//PARD6B//C2CD2L//CHL1//EDA//ADGRF5//C5AR2//ACVR1// GO:0036064 ciliary basal body Cellular component 7 110 492 18698 2.418440503 0.026215341 1 1.581444481 0.014227642 PIFO//TTLL6//TBC1D7//WDR5B//AHI1//CCDC88A//RP2// GO:0005581 collagen trimer Cellular component 6 88 492 18698 2.591186253 0.028541124 1 1.544528935 0.012195122 COL27A1//COL14A1//COLEC10//C1QTNF3//EDA//LOX// GO:0048471 perinuclear region of cytoplasm Cellular component 26 668 492 18698 1.479200136 0.030898462 1 1.510063143 0.052845528 ADAM10//SYT6//TRAIP//CX3CR1//EGFR//FAT1//CASC3//LMTK2//USP33//RAP1GAP2//ITGA2//SEPT2//ODC1//STK26//PI4KB//HIF1AN//UNC45A//JCAD//SET//AURKA//CDK2AP1//ITM2C//MS4A3//PRDX6//NOS1AP//CDC5L// GO:0044444 cytoplasmic part Cellular component 274 9626 492 18698 1.081769564 0.032198627 1 1.492162649 0.556910569 DIS3//WIPI2//ULK2//KIF19//ATG14//PIK3R4//SEPT2//GLYAT//TDRKH//DEPP1//MRPL3//TUSC2//MRPL10//CYB5R3//ABAT//EYA2//FASTKD2//HEBP2//BCLAF3//GALC//MPC2//BLOC1S2//MRM2//HCCS//ACAT1//MUTYH//NKTR//DNAJC27//PDHB//MTRF1L//MCUB//MRPS10//NIPSNAP3B//ABHD10//MRS2//AARS2//MTUS1//NGB//MARC1//TXN//UROS//NARS2//CLPP//NFS1//OXNAD1//MGME1//PRDX6//NOS1AP//GLB1L//ZBTB33//FARSB//YAF2//FAM13A//STAMBP//SRSF8//NUPL2//SEC23IP//SEC63//XPOT//CNTROB//KRT74//KLF6//ACOT12//SYT6//CTH//KCTD7//PHOSPHO1//DCC//DHCR7//DIAPH2//DSG3//DUSP6//ELK4//FBXO15//CASC3//LMTK2//ZHX2//NCBP2//RPIA//NT5C2//ABCF1//USP33//RAP1GAP2//FAM120A//DNAJC9//FLRT3//LSM4//PNISR//LTN1//GHR//ANKRD1//CACYBP//DENND2A//RND1//GCLM//TMEM97//GMDS//TTLL6//N6AMT1//PACSIN3//GYG1//HAL//KRTAP8-1//IFIT1//IMPA2//AR//ARRB2//ODC1//CEP83//COPS4//HSD17B11//TBC1D7//PDE1C//LARS//UPB1//RAPGEF6//STK26//PFKFB4//PI4KB//PRRX1//MTMR12//LZTFL1//AHI1//SHQ1//RIC8B//YOD1//CNOT11//G2E3//HIF1AN//LIMS2//CCDC88A//UNC45A//PSMB5//PSMD12//KIDINS220//ZFAT//RRAGD//RASGRF2//EXOC4//NCAPG//SET//SUDS3//BMI1//GPBP1//MTMR9//STAT2//AURKA//SYT1//TTN//UBE3A//UBP1//CA3//PSAPL1//C1ORF116//SNRNP25//TTLL7//ARHGAP28//CBLL1//MCMBP//DENND2D//CDK2AP1//TRIM8//CDT1//SMC1A//NUDT12//TRAPPC9//ITCH//PARD6B//SPSB2//STON2//EIF3C//RIOK3//BMF//PRC1//USP8//FMNL3//CNOT9//CYTH2//CYTH1//COPS2//SEC24C//TTC37//FARP2//OSBPL2//CDC25A//CALCRL//CTSZ//FGD5//HACD2//KDSR//GOLT1B//TXNDC11//GPR85//FAM20A//P3H2//ATL2//DHDDS//ELOVL7//PGAP1//B3GNT5//ADAM10//PAK4//COLEC10//GGA2//RP2//GALNT11//ITM2C//SAA1//LRRC47//PIFO//ADGRF5//RGS17//ANP32E//ADAMTS1//TRAIP//CX3CR1//EGFR//FAT1//ITGA2//JCAD//MS4A3//CDC5L//PEG3//WDR72//GCGR//BLOC1S5//RALA//TDRD1//PXT1//PEX12//ABCD4//RBM3//CNGA4//MIA3//GOLGA7B//HS3ST4//GPC5//FUCA2//GCG//SERPIND1//COL14A1//EVA1A//COL27A1//SPTSSA//EDA//DDN//PAFAH2//SLC28A3//LRRC8E//RNF170//C2CD2L//MAN2B1//MYOM1//DUSP27//KAT2B//CCDC68//FAM110C//CD302//C12ORF66//PLAC8//SLC18A2//SCAMP1//ARFGEF3//FRMPD3//SYT2//STK10//ATP1B3//SLC25A15//SFXN2//GRIK2//TGFBI//PRAF2//C2CD4A//SEMA4C// GO:0002178 palmitoyltransferase complex Cellular component 2 11 492 18698 6.909830007 0.032475558 1 1.488443379 0.004065041 SPTSSA//GOLGA7B// GO:0042555 MCM complex Cellular component 2 11 492 18698 6.909830007 0.032475558 1 1.488443379 0.004065041 MCM4//MCMBP// GO:0097038 perinuclear endoplasmic reticulum Cellular component 2 11 492 18698 6.909830007 0.032475558 1 1.488443379 0.004065041 ADAM10//SYT6// GO:0035578 azurophil granule lumen Cellular component 6 91 492 18698 2.50576253 0.032907671 1 1.482702848 0.012195122 CYB5R3//HEBP2//FUCA2//MAN2B1//PLAC8//PRDX6// GO:0000779 condensed chromosome, centromeric region Cellular component 7 117 492 18698 2.273747481 0.035039688 1 1.455439775 0.014227642 NUDCD2//SEPT2//CDT1//SMC1A//AURKA//NCAPD3//NCAPG// GO:0030688 preribosome, small subunit precursor Cellular component 2 12 492 18698 6.33401084 0.038303328 1 1.416763485 0.004065041 NOP14//RIOK3// GO:0060198 clathrin-sculpted vesicle Cellular component 2 12 492 18698 6.33401084 0.038303328 1 1.416763485 0.004065041 SYT1//SLC18A2// GO:0005775 vacuolar lumen Cellular component 9 172 492 18698 1.988584799 0.038555742 1 1.413910934 0.018292683 CYB5R3//HEBP2//FUCA2//MAN2B1//PLAC8//PRDX6//GPC5//GALC//GYG1// GO:0005578 proteinaceous extracellular matrix Cellular component 16 375 492 18698 1.621506775 0.040452495 1 1.393054684 0.032520325 FGF9//P3H2//TGFBI//ADAMTS1//ABI3BP//COL14A1//COL27A1//CHL1//SBSPON//PHOSPHO1//GPC5//FLRT3//LOX//MMP26//NYX//SLITRK2// GO:0030658 transport vesicle membrane Cellular component 10 203 492 18698 1.872121431 0.04279674 1 1.368589307 0.020325203 SEC23IP//SEC24C//SYT1//SLC18A2//SYT2//C2CD4A//SYT6//SEMA4C//SCAMP1//ARFGEF3// GO:0008021 synaptic vesicle Cellular component 9 176 492 18698 1.94338969 0.043565642 1 1.360855881 0.018292683 SYT2//C2CD4A//SYT6//SEMA4C//SLC18A2//SYT1//SCAMP1//COPS4//STON2// GO:0033267 axon part Cellular component 15 353 492 18698 1.614903614 0.047567669 1 1.322688126 0.030487805 CTSZ//LMTK2//PTPRO//TRPC5//CYTH2//CCK//GRIK2//SLC18A2//SYT1//AURKA//FLRT3//ITGA2//BLOC1S2//BLOC1S5//EXOC4// GO:0005623 cell Cellular component 456 16915 492 18698 1.024525785 0.048737602 1 1.312135842 0.926829268 ZBTB33//ADAM10//CALCRL//STAMBP//CHL1//LILRB4//SLC46A1//SLC52A3//FAT3//SYT2//OR6P1//RAET1E//C2CD4A//SYT6//ADRA2B//CTSZ//CX3CR1//KCTD7//DGKB//DCC//DSG3//EDA//EGFR//FAT1//FCGR2B//ADGRF5//VSTM2A//GPC5//ZHX2//RAP1GAP2//FAM120A//DNAJC9//FLRT3//GABRB1//GCG//GCGR//OR10J1//RGS17//OR4D1//GHR//GIPR//FAM155B//C5AR2//RND1//TMEM97//GPR20//NKAIN3//GRIK2//PACSIN3//GYPA//HTR2B//AQP7//AR//ITGA2//ITGB8//KCNA3//KCNJ16//LIFR//ARRB2//OR14J1//NKTR//ATP1B3//OR3A1//P2RY4//DHH//RXFP3//RAPGEF6//CLDN22//GPR85//RALGPS2//ANO1//RIC8B//FLVCR2//LIMS2//CCDC88A//SENP7//MTUS1//PTPRO//RALA//RASGRF2//EXOC4//RP2//SLC28A3//SLC39A8//GPBP1//SLC18A2//BMPR2//STAT2//STK10//SYT1//TGFBI//TRPC5//C1ORF116//MCMBP//LRRC8E//ITM2C//ITCH//EVA1A//FRMPD3//MCHR2//PARD6B//SLITRK2//RGS11//CACNA1H//CCRL2//BMF//FMNL3//CYTH2//CYTH1//MS4A3//SCAMP1//CELSR1//KANSL1L//KAT8//KAT2B//BRF1//SEC23IP//CNGA4//MIA3//GOLGA7B//GOLT1B//STK26//PI4KB//GALNT11//TRAPPC9//B3GNT5//SEC24C//HS3ST4//SEPT2//FBXO15//BMI1//CBLL1//DIS3//MTREX//ZBTB18//CCDC36//TTN//SMC1A//NCAPG//NUDCD2//MAP3K15//NPR3//WDR5B//NYX//TUFT1//CCDC68//NME5//WIPI2//ULK2//ATG14//PSMB5//PSMD12//UBE3A//ZNF330//SYCP1//CDT1//NCAPD3//AURKA//NSMCE1//MCM4//HMGN1//HMGN2//HNRNPK//ASXL3//TEX12//ANP32E//FAM110C//PRC1//BLOC1S2//LSM4//CNOT9//KLF6//ANKRD1//KRTAP8-1//FGD5//OPN5//KIF19//PIK3R4//ABCD4//FUCA2//GALC//LARS//RRAGD//PSAPL1//GLYAT//TDRKH//DEPP1//MRPL3//TUSC2//MRPL10//CYB5R3//ABAT//EYA2//FASTKD2//HEBP2//BCLAF3//MPC2//MRM2//HCCS//ACAT1//MUTYH//DNAJC27//PDHB//MTRF1L//MCUB//MRPS10//NIPSNAP3B//ABHD10//MRS2//AARS2//NGB//MARC1//TXN//UROS//NARS2//CLPP//NFS1//OXNAD1//MGME1//PRDX6//NOS1AP//GLB1L//FARSB//YAF2//FAM13A//SRSF8//NUPL2//SEC63//XPOT//CNTROB//KRT74//ACOT12//CTH//PHOSPHO1//DHCR7//DIAPH2//DUSP6//ELK4//CASC3//LMTK2//NCBP2//RPIA//NT5C2//ABCF1//USP33//PNISR//LTN1//CACYBP//DENND2A//GCLM//GMDS//TTLL6//N6AMT1//GYG1//HAL//IFIT1//IMPA2//ODC1//CEP83//COPS4//HSD17B11//TBC1D7//PDE1C//UPB1//PFKFB4//PRRX1//MTMR12//LZTFL1//AHI1//SHQ1//YOD1//CNOT11//G2E3//HIF1AN//UNC45A//KIDINS220//ZFAT//SET//SUDS3//MTMR9//UBP1//CA3//SNRNP25//TTLL7//ARHGAP28//DENND2D//CDK2AP1//TRIM8//NUDT12//SPSB2//STON2//EIF3C//RIOK3//USP8//COPS2//TTC37//FARP2//OSBPL2//CDC25A//PXT1//PEX12//SLC17A4//GABRP//GJA5//PCDHA5//SEMA6A//SLC4A11//ACVR1//CD302//FSBP//MBNL2//POP7//ADAR//NCOA2//ZNF689//ZNF813//ZNF491//PIFO//RBM45//ZNF578//ZNF600//ZNF780B//GADD45A//DUSP1//EGR4//EYA1//ZNF507//DDN//TSPYL4//OTP//RNASEH1//ZNF345//NAP1L5//ZNF707//FBXO43//SAP30BP//HLX//HOXA5//ANKRD34B//ZSWIM9//TBPL2//ZNF888//LYSMD1//VWA5A//LOX//ASCL1//ARGFX//LUZP4//CDK17//ZNF589//SIRT6//PPIL1//PEG3//PKNOX1//RAVER2//SOX6//CHD7//CMTR2//PLEKHG1//NCOA5//PTPN14//RBM3//C11ORF1//SIX3//ZFP69B//TCEA1//WEE1//ZNF19//ZNF33A//ZNF45//ZNF202//FTO//ZNF426//TFEB//TMEM53//USB1//CSRNP2//HASPIN//BRIP1//NR0B2//UBASH3B//NOP14//CDC5L//DPY19L3//PAK4//COLEC10//MSI2//ADM//ROPN1B//CCDC125//FGF9//KLHDC10//SIK3//WDR72//CHRDL2//GJB3//NKIRAS2//RWDD1//RIPK4//KLHL24//ARHGEF40//TDRD1//LRRC4C//SNTB1//ZNF185//BCAS1//DUSP27//PPP1R17//ELL2//LIN9//SCAF4//FIP1L1//RNF113B//TRAIP//SLC25A15//SFXN2//C12ORF66//MAN2B1//HACD2//KDSR//TXNDC11//FAM20A//P3H2//ATL2//DHDDS//ELOVL7//PGAP1//SERPIND1//COL14A1//COL27A1//SPTSSA//PAFAH2//RNF170//C2CD2L//GGA2//BLOC1S5//ARFGEF3//NCBP2L//MYOM1//SAA1//LRRC47//PRAF2//SEMA4C//CORO2A//CCK//ADAMTS1//KLHDC7A//KBTBD3//KBTBD12//JCAD//R3HCC1//PLAC8//BRMS1L//GPX5//C1QTNF3//XCL1// GO:0017046 peptide hormone binding Molecular function 7 42 482 17548 6.067773167 1.32E-04 0.171628717 3.878015045 0.014522822 C2CD2L//CALCRL//GCGR//GHR//GIPR//NPR3//ACVR1// GO:0042562 hormone binding Molecular function 9 94 482 17548 3.485742032 1.11E-03 0.720836773 2.953738072 0.018672199 AR//GCGR//GHR//GIPR//NPR3//ACVR1//C2CD2L//EGFR//CALCRL// GO:0005085 guanyl-nucleotide exchange factor activity Molecular function 18 323 482 17548 2.028852948 0.003719135 1 2.429558114 0.037344398 ARFGEF3//CYTH2//CYTH1//EGFR//FGF9//RASGRF2//FGD5//ARHGEF40//PLEKHG1//FARP2//DENND2A//DENND2D//TRAPPC9//DIS3//GCGR//RAPGEF6//RALGPS2//RIC8B// GO:0016874 ligase activity Molecular function 11 159 482 17548 2.518698296 0.004527131 1 2.34417697 0.022821577 GCLM//AARS2//NARS2//LARS//FARSB//LRRC47//ACAT1//TTLL6//TTLL7//ITCH//TTLL2// GO:0051020 GTPase binding Molecular function 30 665 482 17548 1.642404767 0.005535845 1 2.256816098 0.062240664 FGD5//DIS3//GCGR//RAPGEF6//RALGPS2//RIC8B//RASGRF2//ARFGEF3//CYTH2//CYTH1//EGFR//FGF9//ARHGEF40//PLEKHG1//FARP2//XPOT//DIAPH2//PARD6B//FMNL3//DENND2A//DENND2D//TRAPPC9//PIFO//TBC1D7//USP33//EXOC4//GGA2//PAK4//ATG14//RRAGD// GO:0004725 protein tyrosine phosphatase activity Molecular function 8 100 482 17548 2.91253112 0.00627334 1 2.20250115 0.01659751 DUSP1//PTPRO//DUSP6//EYA1//EYA2//PTPN14//UBASH3B//CDC25A// GO:0004812 aminoacyl-tRNA ligase activity Molecular function 5 44 482 17548 4.137118069 0.006883822 1 2.162170367 0.010373444 AARS2//NARS2//LARS//FARSB//LRRC47// GO:0016875 ligase activity, forming carbon-oxygen bonds Molecular function 5 44 482 17548 4.137118069 0.006883822 1 2.162170367 0.010373444 AARS2//NARS2//LARS//FARSB//LRRC47// GO:0016791 phosphatase activity Molecular function 15 270 482 17548 2.022591056 0.007926319 1 2.100928441 0.031120332 PFKFB4//MTMR9//CDC25A//DUSP6//EYA1//EYA2//PTPN14//PTPRO//UBASH3B//DUSP1//DUSP27//NT5C2//IMPA2//PHOSPHO1//CA3// GO:0005086 ARF guanyl-nucleotide exchange factor activity Molecular function 3 20 482 17548 5.460995851 0.016584123 1 1.780307495 0.006224066 ARFGEF3//CYTH2//CYTH1// GO:0016881 acid-amino acid ligase activity Molecular function 3 21 482 17548 5.200948429 0.018961415 1 1.722129253 0.006224066 GCLM//TTLL6//TTLL7// GO:0019212 phosphatase inhibitor activity Molecular function 4 39 482 17548 3.734014257 0.02165411 1 1.664459655 0.008298755 LMTK2//SET//PPP1R17//ANP32E// GO:0042578 phosphoric ester hydrolase activity Molecular function 17 364 482 17548 1.700310063 0.023926866 1 1.621114188 0.03526971 PDE1C//PFKFB4//MTMR9//CDC25A//DUSP6//EYA1//EYA2//PTPN14//PTPRO//UBASH3B//DUSP1//DUSP27//NT5C2//IMPA2//PHOSPHO1//CA3//PGAP1// GO:0005515 protein binding Molecular function 338 11565 482 17548 1.064024555 0.025728689 1 1.589582339 0.701244813 SYT1//SEC24C//ANKRD1//AR//SIX3//CDC5L//USP33//ARRB2//SAA1//PSAPL1//HTR2B//RIC8B//CHL1//TTN//DIAPH2//CCDC88A//SNTB1//TRPC5//FMNL3//PARD6B//FGD5//DIS3//GCGR//RAPGEF6//RALGPS2//RASGRF2//ARFGEF3//CYTH2//CYTH1//EGFR//FGF9//ARHGEF40//PLEKHG1//FARP2//ADAM10//ADM//EDA//GCG//RND1//ITGB8//ANGPTL1//FLRT3//HIF1AN//GALNT11//DHH//LIFR//CNOT9//ITGA2//TGFBI//CCK//CTH//PDE1C//XCL1//KIF19//MTUS1//PRC1//PEX12//PIFO//PACSIN3//EYA2//KAT8//NR0B2//KAT2B//XPOT//CACYBP//TTLL6//NCOA2//RALA//BRF1//DENND2A//DENND2D//TRAPPC9//USP8//TBC1D7//WIF1//PTPRO//EXOC4//DUSP1//BMPR2//HACD2//CASC3//ACAT1//SUDS3//NOP14//GADD45A//MYOM1//FAM83C//GHR//AURKA//CDC25A//CSRNP2//MTMR9//STAMBP//CNTROB//HNRNPK//SYT2//C2CD4A//SYT6//CX3CR1//ROPN1B//GRIK2//KIDINS220//SEMA4C//GGA2//JCHAIN//COL14A1//PTPN14//DNAJC9//EIF3C//LMTK2//YOD1//UBASH3B//PRDX6//RGS11//ABAT//SEPT2//KANSL1L//NCAPD3//GCLM//COLEC10//SAA2//CCRL2//SET//ANP32E//LSM4//FSBP//VSTM2A//ZHX2//RPIA//GMDS//GYPA//STK26//CLDN22//LZTFL1//AHI1//ATL2//STAT2//STK10//CBLL1//TRIM8//CLPP//IMPA2//ASCL1//NPR3//ODC1//ACVR1//NFS1//BRMS1L//ASXL3//FAM110C//TTLL7//BLOC1S2//GPC5//C2CD2L//ITCH//ABCF3//UNC45A//UBFD1//RAET1E//PKNOX1//SOX6//RRAGD//SMC1A//NSMCE1//ANO1//TFEB//SLC4A11//CELSR1//PAK4//GABRB1//NOS1AP//CORO2A//ZNF185//ATG14//NUDCD2//SHQ1//RP2//ATP1B3//CDK2AP1//GJA5//BMI1//PRRX1//PI4KB//RIOK3//CACNA1H//PPIL1//ZBTB33//SMLR1//FARSB//YAF2//CALCRL//POP7//GLYAT//TRAIP//ADAR//ZBTB18//SRSF8//LILRB4//NUPL2//SEC23IP//PRAF2//SEC63//TUSC2//MSI2//MRPL10//RBM45//C2ORF50//KLF6//C19ORF25//MOB3C//ITPRIPL1//ADRA2B//CTSZ//KCTD7//DCC//SPTSSA//CYB5R3//CCER1//ELK4//ADCK5//EYA1//FAT1//FCGR2B//NCBP2//ELL2//NT5C2//ABCF1//KLHDC10//RAP1GAP2//DDN//TSPYL4//KIAA0930//SIK3//MTREX//HEBP2//FUCA2//LTN1//WIPI2//RGS17//GIPR//C5AR2//ZNF330//TMEM97//ZNF707//LIN9//N6AMT1//SAP30BP//GYG1//PIK3R4//HLX//HMGN2//HOXA5//KRTAP8-1//ANKRD45//CCDC36//IFIT1//KCNA3//ZSWIM9//MIA3//LYSMD1//FAM102A//LOX//MAGEB2//MAN2B1//MCM4//MUTYH//TXNDC11//CEP83//COPS4//LUZP4//DNAJC27//CDK17//RWDD1//LARS//SIRT6//PDHB//RIPK4//GPR85//MTMR12//FAM20A//KLHL24//ZCCHC10//FAM90A1//EVA1B//CNOT11//G2E3//CHD7//PSMB5//PSMD12//SENP7//LRRC47//SEMA6A//LRRC4C//NCOA5//NGB//RBM3//BLOC1S5//NCAPG//ARMCX5//TTC23//GPBP1//ZFP69B//TCEA1//TUFT1//TXN//UBE3A//WEE1//ZNF202//SMIM2//ZNF426//C1ORF116//SNRNP25//ZC2HC1C//CCDC102B//MCMBP//DHDDS//ELOVL7//LRRC8E//CCDC68//FIP1L1//ITM2C//CDT1//RNF170//NUDT12//NME5//HASPIN//BRIP1//PRRC2B//SPSB2//STON2//TPD52L3//BMF//COPS2//MS4A3//SCAMP1//TTC37//ULK2//OSBPL2// GO:0016788 hydrolase activity, acting on ester bonds Molecular function 30 751 482 17548 1.454326458 0.026160492 1 1.582354095 0.062240664 DIS3//USB1//LARS//PAFAH2//ACOT12//PDE1C//PFKFB4//MTMR9//PGAP1//ZC3H12B//RNASEH1//POP7//SEC23IP//CDC25A//DUSP6//EYA1//EYA2//PTPN14//PTPRO//UBASH3B//DUSP1//DUSP27//NT5C2//MGME1//IMPA2//GOLT1B//PHOSPHO1//CA3//PRDX6//ABHD10// GO:0043995 histone acetyltransferase activity (H4-K5 specific) Molecular function 2 10 482 17548 7.281327801 0.029278147 1 1.53345642 0.004149378 KANSL1L//KAT8// GO:0043996 histone acetyltransferase activity (H4-K8 specific) Molecular function 2 10 482 17548 7.281327801 0.029278147 1 1.53345642 0.004149378 KANSL1L//KAT8// GO:0046972 histone acetyltransferase activity (H4-K16 specific) Molecular function 2 10 482 17548 7.281327801 0.029278147 1 1.53345642 0.004149378 KANSL1L//KAT8// GO:0016846 carbon-sulfur lyase activity Molecular function 2 11 482 17548 6.61938891 0.035143836 1 1.454150833 0.004149378 CTH//HCCS// GO:0019855 calcium channel inhibitor activity Molecular function 2 11 482 17548 6.61938891 0.035143836 1 1.454150833 0.004149378 PACSIN3//MCUB// GO:0061578 Lys63-specific deubiquitinase activity Molecular function 2 11 482 17548 6.61938891 0.035143836 1 1.454150833 0.004149378 STAMBP//YOD1// GO:0042975 peroxisome proliferator activated receptor binding Molecular function 2 12 482 17548 6.067773167 0.041419492 1 1.38279523 0.004149378 ASXL3//NR0B2// GO:0043422 protein kinase B binding Molecular function 2 12 482 17548 6.067773167 0.041419492 1 1.38279523 0.004149378 ARRB2//CCDC88A// GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity Molecular function 2 13 482 17548 5.601021385 0.048078267 1 1.318051195 0.004149378 DUSP1//DUSP6// GO:0070679 inositol 1,4,5 trisphosphate binding Molecular function 2 13 482 17548 5.601021385 0.048078267 1 1.318051195 0.004149378 TRPC5//CYTH2// GO:0019899 enzyme binding Molecular function 76 2301 482 17548 1.202479167 0.048815015 1 1.311446577 0.157676349 CHL1//TTN//PARD6B//FGD5//DIS3//GCGR//RAPGEF6//RALGPS2//RIC8B//RASGRF2//ARFGEF3//CYTH2//CYTH1//EGFR//FGF9//ARHGEF40//PLEKHG1//FARP2//CDC5L//XPOT//DIAPH2//FMNL3//DENND2A//DENND2D//TRAPPC9//PIFO//TBC1D7//USP33//EXOC4//GADD45A//MYOM1//CNOT9//ADAM10//FAM83C//GHR//RND1//AURKA//KAT2B//PRC1//CDC25A//CSRNP2//MTMR9//GGA2//PTPN14//LMTK2//GRIK2//CASC3//CACYBP//ARRB2//YOD1//RALA//UBASH3B//PRDX6//ABAT//KANSL1L//GCLM//ANKRD1//SUDS3//SIX3//BRMS1L//CCDC88A//STAT2//ITCH//PAK4//NOS1AP//ATG14//RRAGD//AR//ATP1B3//TRPC5//CDK2AP1//RIOK3//HACD2//ACAT1//KAT8//NOP14// GO:0017048 Rho GTPase binding Molecular function 9 173 482 17548 1.893987 0.04970946 1 1.303560957 0.018672199 FGD5//ARHGEF40//PLEKHG1//RASGRF2//FARP2//PAK4//DIAPH2//PARD6B//FMNL3// hsa00511 Other glycan degradation - Homo sapiens (human) pathway 2 95 18 7906 1.93E-02 1.00E+00 1.714665 0.021053 FUCA2//MAN2B1 hsa04977 Vitamin digestion and absorption - Homo sapiens (human) pathway 2 95 24 7906 3.32E-02 1.00E+00 1.478621 0.021053 SLC46A1//SLC52A3 hsa00062 Fatty acid elongation - Homo sapiens (human) pathway 2 95 27 7906 4.13E-02 1.00E+00 1.384266 0.021053 ELOVL7//HACD2 hsa01040 Biosynthesis of unsaturated fatty acids - Homo sapiens (human) pathway 2 95 27 7906 4.13E-02 1.00E+00 1.384266 0.021053 ELOVL7//HACD2