ID,Family,Receptor,Output,Ref Affinity measurement,Ref Potency measurement,Power,Std Error,R squared,P value,signf.,n
1,Cytokine Receptor,IL-2R beta,CD25 – pSTAT5 (NK cells),Levin 2012,Levin 2012,0.546,0.031,0.9935,0.0032,sig,4
2,Cytokine Receptor,IL-2R beta,CD25 – %pSTAT5 (T cells),Levin 2012,Levin 2012,0.743,0.047,0.9922,0.0039,sig,4
3,Cytokine Receptor,IL-13Rα1,pSTAT6,Moraga 2015,Moraga 2015,0.471,0.065,0.8018,<0.0001,sig,9
4,Cytokine Receptor,IL-13Rα2,Proliferation,Moraga 2015,Moraga 2015,0.394,0.243,0.2735,0.1485,ns,9
5,Cytokine Receptor,IL-13Rα2,CD86,Moraga 2015,Moraga 2015,0.442,0.085,0.8999,0.0139,sig,
6,Cytokine Receptor,IL-13Rα1,CD205,Moraga 2015,Moraga 2015,0.421,0.048,0.9624,0.0031,sig,9
7,Cytokine Receptor,IFNAR1/IFNAR2,antiviral,Thomas C. 2011,Thomas C. 2011,0.7137,0.1125,0.7854,<0.0001,sig,13
8,Cytokine Receptor,IFNAR1/IFNAR2,antiproliferation,Thomas C. 2011,Thomas C. 2011,1.329,0.1068,0.9336,<0.0001,sig,13
9,Cytokine Receptor,IFN-gammaR1-IL-10Rbeta,pSTAT1,Mendoza 2017,Mendoza 2017,0.0242,0.0459,0.02985,0.6115,ns,11
10,Cytokine Receptor,IFN-gammaR1-IL-10Rbeta,antiviral,Mendoza 2017,Mendoza 2017,0.0341,0.0628,0.0318,0.5999,ns,11
11,Cytokine Receptor,IFN-gammaR1-IL-10Rbeta,antiproliferation,Mendoza 2017,Mendoza 2017,0.4963,0.1364,0.5954,0.0054,sig,11
12,Cytokine Receptor,gp130 (and IL6R alpha),pSTAT1,Martinez-Fabregas 2019,Martinez-Fabregas 2019,0.5438,0.2363,0.8411,0.261,ns,3
13,Cytokine Receptor,gp130 (and IL6R alpha),pSTAT3,Martinez-Fabregas 2019,Martinez-Fabregas 2019,0.5194,0.316,0.5746,0.242,ns,4
14,RTK,EGFR,growth rate,Reddy 1996,Reddy 1996,0.552,0.101,0.9677,0.1151,ns,3
15,RTK,c-Kit,pERK,Ho 2017,Ho 2017,0.834,0.141,0.9456,0.0276,sig,4
16,RTK,c-Kit,pAKT,Ho 2017,Ho 2017,0.882,0.135,0.9555,0.0225,sig,4
17,GPCR,A2A receptor,whole cell,Guo 2012,Guo 2012,0.289,0.201,0.2062,0.1874,ns,10
18,GPCR,A2A receptor,cAMP,Guo 2012,Guo 2012,0.706,0.291,0.4239,0.0414,sig,10
19,GPCR,M3 muscarinic receptor,Calcium,Sykes 2009,Sykes 2009,0.7717,0.5336,0.2949,0.2077,ns,7
20,GPCR,M3 muscarinic receptor,GTPyS Binding,Sykes 2009,Sykes 2009,0.5478,0.1809,0.6471,0.0292,sig,7
21,GPCR,CXCR4,Voltage,Guyon 2013,Guyon 2013,0.5686,0.4035,0.3983,0.2536,ns,5
22,GPCR,CXCR3,Calcium mobilization,Heise 2005,Heise 2005,0.7346,0.0333,0.998,0.0288,sig,3
23,GPCR,CXCR3,GTP gamma S Binding,Heise 2005,Heise 2005,1.056,0.0039,1,0.0024,sig,3
24,GPCR,CXCR3,Migrated Cells,Heise 2005,Heise 2005,0.5609,Perfect line,1,,ns,2
25,CAR,C6.5 (scFc against ErbB2),INF gamma (Plate),Chmielewski 2004,Chmielewski 2004,0.5249,0.0275,0.9919,0.0003,sig,5
26,CAR,ErB2,CD107,Liu 2015,Liu 2015,1.058,0.1385,0.9669,0.0167,sig,4
27,CAR,ErB2,Proliferation,Liu 2015,Liu 2015,0.6409,0.1762,0.8686,0.068,ns,4
28,CAR,DNA-CAR,pERK,Taylor 2017,Taylor 2017,1.2223,0.1728,0.9616,0.0194,sig,4
29,BCR,D1.3,IL2,Batista 1998,Batista 1998,1.383,0.177,0.9386,0.0014,sig,6
30,BCR,HyHEL10,IL2,Batista 1998,Batista 1998,1.266,0.119,0.9826,0.0088,sig,4