Key,Item Type,Publication Year,Author,Title,Publication Title,ISBN,ISSN,DOI,Url,Abstract Note,Date,Date Added,Date Modified,Access Date,Pages,Num Pages,Issue,Volume,Number Of Volumes,Journal Abbreviation,Short Title,Series,Series Number,Series Text,Series Title,Publisher,Place,Language,Rights,Type,Archive,Archive Location,Library Catalog,Call Number,Extra,Notes,File Attachments,Link Attachments,Manual Tags,Automatic Tags,Editor,Series Editor,Translator,Contributor,Attorney Agent,Book Author,Cast Member,Commenter,Composer,Cosponsor,Counsel,Interviewer,Producer,Recipient,Reviewed Author,Scriptwriter,Words By,Guest,Number,Edition,Running Time,Scale,Medium,Artwork Size,Filing Date,Application Number,Assignee,Issuing Authority,Country,Meeting Name,Conference Name,Court,References,Reporter,Legal Status,Priority Numbers,Programming Language,Version,System,Code,Code Number,Section,Session,Committee,History,Legislative Body KS5L8PM2,conferencePaper,2018,"Daher, Salam; Hochreiter, Jason; Norouzi, Nahal; Gonzalez, Laura; Bruder, Gerd; Welch, Greg",Physical-Virtual Agents for Healthcare Simulation,Proceedings of the 18th International Conference on Intelligent Virtual Agents,978-1-4503-6013-5,,10.1145/3267851.3267876,http://doi.acm.org/10.1145/3267851.3267876,,2018,13/11/2018 10:47,14/04/2020 08:34,,99–106,,,,,,,IVA '18,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 110; neurological assessment; patient simulator; Physical-virtual agents,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, SRJNHR57,conferencePaper,2018,"Sarajlic, Olesya; He, Xiaochun; Sarajlic, Semir; Wei, Ting-Cun",Computational Challenges and Opportunities of Simulating Cosmic Ray Showers at Global Scale,Proceedings of the Practice and Experience on Advanced Research Computing,978-1-4503-6446-1,,10.1145/3219104.3229281,http://doi.acm.org/10.1145/3219104.3229281,,2018,13/11/2018 10:47,14/04/2020 08:35,,42:1–42:7,,,,,,,PEARC '18,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100; cosmic rays; ECRS; GEANT4; geomagnetic field; XSEDE,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RTHJJ6MT,conferencePaper,2018,"Wilder, Bryan; Ou, Han Ching; de la Haye, Kayla; Tambe, Milind",Optimizing Network Structure for Preventative Health,Proceedings of the 17th International Conference on Autonomous Agents and MultiAgent Systems,,,,http://dl.acm.org/citation.cfm?id=3237383.3237507,,2018,13/11/2018 10:47,14/04/2020 08:35,,841–849,,,,,,,AAMAS '18,,,,International Foundation for Autonomous Agents and Multiagent Systems,"Richland, SC",,,,,,,,,,,,00; 100; network design; preventative health; social networks,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ZRVHDXWV,conferencePaper,2018,"Singh, Meghendra; Marathe, Achla; Marathe, Madhav V.; Swarup, Samarth",Behavior Model Calibration for Epidemic Simulations,Proceedings of the 17th International Conference on Autonomous Agents and MultiAgent Systems,,,,http://dl.acm.org/citation.cfm?id=3237383.3237943,,2018,13/11/2018 10:47,14/04/2020 08:35,,1640–1648,,,,,,,AAMAS '18,,,,International Foundation for Autonomous Agents and Multiagent Systems,"Richland, SC",,,,,,,,,,,,100; agent based simulation; human behavior modeling; markov decision processes,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5JUR33DW,conferencePaper,2018,"Damasceno, Lidiane; Werneck, Vera Maria B.; Schots, Marcelo",Metric-based Evaluation of Multiagent Systems Models,Proceedings of the 10th International Workshop on Modelling in Software Engineering,978-1-4503-5735-7,,10.1145/3193954.3193960,http://doi.acm.org/10.1145/3193954.3193960,,2018,13/11/2018 10:47,14/04/2020 08:34,,67–74,,,,,,,MiSE '18,,,,ACM,"New York, NY, USA",,,,,,,,,,,,******To read; 00; 100; metrics; model evaluation; multiagent systems; quality assurance,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6VT9T6H5,conferencePaper,2018,"Ramalho, Edneide; Codina, Daniel López; Prats, Clara; Cristino, Claudio; Lorena, Virginia; Albuquerque, Jones",Using Mathematical Modeling to Simulate Chagas Disease Spread by Congenital and Blood Transfusion Routes,Proceedings of the 2018 International Conference on Digital Health,978-1-4503-6493-5,,10.1145/3194658.3194661,http://doi.acm.org/10.1145/3194658.3194661,,2018,13/11/2018 10:47,14/04/2020 08:35,,110–110,,,,,,,DH '18,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100; blood transfusion transmission; chagas disease; congenital transmission; mathematical modeling; simulation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2FMMDXSH,conferencePaper,2018,"Zhang, Hongxiang; Wang, Lizhen",Prescription Fraud Detection Through Statistic Modeling,Proceedings of 2018 International Conference on Mathematics and Artificial Intelligence,978-1-4503-6420-1,,10.1145/3208788.3208803,http://doi.acm.org/10.1145/3208788.3208803,,2018,13/11/2018 10:47,14/04/2020 08:35,,85–89,,,,,,,ICMAI '18,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100; off-line; online; prescription fraud; risk function; statistical model,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9BEM6D3S,journalArticle,2018,"Toth, Edward; Chawla, Sanjay",GT$\Delta$: Detecting Temporal Changes in Group Stochastic Processes,ACM Trans. Knowl. Discov. Data,,1556-4681,10.1145/3183346,http://doi.acm.org/10.1145/3183346,,2018-04,13/11/2018 10:47,14/04/2020 08:35,,39:1–39:24,,4,12,,,,,,,,,,,,,,,,,,,,,00; 100; anomaly detection; Group change detection; time series analysis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, D4855Z2J,conferencePaper,2018,"Watari, Daichi; Taniguchi, Ittetsu; Onoye, Takao",Soh Aware Battery Management Optimization on Decentralized Energy Network,Proceedings of the 9th ACM/IEEE International Conference on Cyber-Physical Systems,978-1-5386-5301-2,,10.1109/ICCPS.2018.00042,https://doi.org/10.1109/ICCPS.2018.00042,,2018,13/11/2018 10:47,14/04/2020 08:35,,337–338,,,,,,,ICCPS '18,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100; battery management; decetralized energy network; MIP optimization; SoH degradation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2A2U34I4,conferencePaper,2018,"Pepino, Alessandro; Vallefuoco, Ersilia; Cuccaro, Patrizia; D'Onofrio, Gaetano",Simulation Model for Analysis and Management of the No-show in Outpatient Clinic,Proceedings of the 10th International Conference on Computer Modeling and Simulation,978-1-4503-6339-6,,10.1145/3177457.3177473,http://doi.acm.org/10.1145/3177457.3177473,"In outpatient management, the lead-time is a critical issue due to its important negative effect on healthcare quality perception. In particular, it generates the phenomenon of ""no-show"": when patients do not attend their scheduled appointments. In this study, we analyze the process of outpatient booking and its critical issues; in particular, we propose a simulation model to evaluate some different approaches. From our results, the lists cleaning can be considered a good tool to manage and reduce the no-show.",2018,13/11/2018 10:47,14/04/2020 08:34,,236–241,,,,,,,ICCMS 2018,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; BPM; Discrete event simulation; E-health; healthcare; no-show; outpatient; Review,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 78IGAYNC,conferencePaper,2017,"Solid, Kent; Komarudin",Water Truck Routing and Scheduling Optimization in Mining Operations with Inventory Function Based on Mixed Integer Linear Programming,Proceedings of the 2017 International Conference on Industrial Design Engineering,978-1-4503-4866-9,,10.1145/3178264.3178288,http://doi.acm.org/10.1145/3178264.3178288,,2017,13/11/2018 10:47,14/04/2020 08:35,,127–132,,,,,,,ICIDE 2017,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100; Capacitated Arc Routing Problem; Coal & mineral mining; dust pollution; inventory function; mixed integer linear programming; optimization; water truck,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MCDEQRZ3,conferencePaper,2017,"Celik, Bilge; Van Gorp, Pieter M. E.; Snoeck, Andre C. J.; van Riet, Remi C.; de Winter, Peter J.; Wilbik, Anna",A Model Based Simulation Toolkit for Evaluating Renal Replacement Policies,Proceedings of the 2017 Winter Simulation Conference,978-1-5386-3427-1,,,http://dl.acm.org/citation.cfm?id=3242181.3242420,,2017,13/11/2018 10:47,14/04/2020 08:34,,225:1–225:12,,,,,,,WSC '17,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NAFEIZNZ,conferencePaper,2017,"Raghothama, Jayanth; Hanchi, Hamza; Meijer, Sebastiaan","Hybrid, Composable Approach to Simulations in Healthcare Operations and Management",Proceedings of the 2017 Winter Simulation Conference,978-1-5386-3427-1,,,http://dl.acm.org/citation.cfm?id=3242181.3242427,"Simulation has been used for modeling in healthcare for many decades. Ranging from the modeling of physiological processes to group dynamics to the modeling of strategic and system-wide models of healthcare provision, simulation promises to be an effective approach to analyze healthcare operations. Effective application of simulations in healthcare operations requires that simulation deal with wide variability and unpredictability in workflow processes, the complexity of healthcare organizations and enables the participation of human experts in the modeling and operations processes. In this paper, based on requirements drawn from a participatory simulation with healthcare practitioners, we define a hybrid, composable approach to healthcare simulations. Both the participatory simulation and the composable simulation are applied in the context of the New Karolinska Solna hospital in Sweden, a highly specialized new hospital. Results point to the need to accounting for variability in workflow processes and integration with existing IT infrastructure in hospitals.",2017,13/11/2018 10:47,14/04/2020 08:34,,232:1–232:12,,,,,,,WSC '17,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,320; hybrid simulation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8SJ3SU6D,conferencePaper,2017,"Melzner, Jürgen",Acquisition and Processing of Input Data for an Object: Oriented Safety Risk Simulation in Building Construction,Proceedings of the 2017 Winter Simulation Conference,978-1-5386-3427-1,,,http://dl.acm.org/citation.cfm?id=3242181.3242387,,2017,13/11/2018 10:47,14/04/2020 08:34,,195:1–195:11,,,,,,,WSC '17,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RXI5K3UM,conferencePaper,2017,"Zhu, Zhengqiu; Chen, Bin; Qiu, Sihang; Wang, Rongxiao; Ma, Liang; Qiu, Xiaogang",The GIS-Based Approach for Optimal Design of Air Quality Monitoring Network for Management of Chemical Clusters,Proceedings of the 3rd ACM SIGSPATIAL Workshop on Emergency Management Using,978-1-4503-5493-6,,10.1145/3152465.3152479,http://doi.acm.org/10.1145/3152465.3152479,,2017,13/11/2018 10:47,14/04/2020 08:35,,13:1–13:8,,,,,,,EM-GIS'17,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100; Air quality monitoring network; Atmospheric dispersion simulation system; Bayesian maximum entropy; Multi-objective optimization model,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BJT9B33M,journalArticle,2017,"Cui, Tiansong; Chen, Shuang; Wang, Yanzhi; Nazarian, Shahin; Pedram, Massoud",Optimal Control of PEVs with a Charging Aggregator Considering Regulation Service Provisioning,ACM Trans. Cyber-Phys. Syst.,,2378-962X,10.1145/3086507,http://doi.acm.org/10.1145/3086507,,2017-08,13/11/2018 10:47,14/04/2020 08:34,,23:1–23:23,,4,1,,,,,,,,,,,,,,,,,,,,,00; 100; charging aggregator; dynamic energy pricing; Plug-in electric vehicle (PEV); regulation service (RS) reserve; state-of-health (SoH) degradation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, P5VU3ERB,conferencePaper,2017,"Schuler, Andreas",Application of Search-based Software Engineering Methodologies for Test Suite Optimization and Evolution in Mission Critical Mobile Application Development,Proceedings of the 2017 11th Joint Meeting on Foundations of Software Engineering,978-1-4503-5105-8,,10.1145/3106237.3119876,http://doi.acm.org/10.1145/3106237.3119876,,2017,13/11/2018 10:47,14/04/2020 08:35,,1034–1037,,,,,,,ESEC/FSE 2017,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100; mobile application development; multi-objective optimization; test automation; test suite optimization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, L6DAS3PS,conferencePaper,2017,"Zhbannikov, Ilya Y.; Arbeev, Konstantin G.",Stochastic Process Model and Its Applications to Analysis of Longitudinal Data,"Proceedings of the 8th ACM International Conference on Bioinformatics, Computational Biology,and Health Informatics",978-1-4503-4722-8,,10.1145/3107411.3107496,http://doi.acm.org/10.1145/3107411.3107496,,2017,13/11/2018 10:47,14/04/2020 08:35,,630–630,,,,,,,ACM-BCB '17,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100; life tables; longitudinal data; quadratic hazard; risk factors; stochastic process model,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 63C9QR5Y,journalArticle,2017,"Amant, Kirk St.",The Cultural Context of Care in International Communication Design: A Heuristic for Addressing Usability in International Health and Medical Communication,Commun. Des. Q. Rev,,2166-1200,10.1145/3131201.3131207,http://doi.acm.org/10.1145/3131201.3131207,,2017-08,13/11/2018 10:47,14/04/2020 08:34,,62–70,,2,5,,,,,,,,,,,,,,,,,,,,,00; 100; care; context; health and medical; international; patients; variables,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UL5UBUE7,conferencePaper,2017,"Kassem, Ahmad; Yildirim, Umut Ozan; Turğut, Kadir Anil; Wiil, Uffe Kock; Özyer, Tansel; Alhajj, Reda",Effectiveness of Mobile Electrocardiogram in Healthcare: From Mobile Application and Development to Community Reaction,Proceedings of the 2017 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining 2017,978-1-4503-4993-2,,10.1145/3110025.3120985,http://doi.acm.org/10.1145/3110025.3120985,,2017,13/11/2018 10:47,14/04/2020 08:34,,896–903,,,,,,,ASONAM '17,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 110; chronic disease; CVD; ECG; mobile application; remote monitoring,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KL5VJXDB,conferencePaper,2017,"Durcinoska, Ivana; Chung, Kon Shing Kenneth; Young, Jane; Solomon, Michael J",Social Networks and Healthcare Coordination: Lessons Learned from an Australian Cancer Care Survey,Proceedings of the 2017 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining 2017,978-1-4503-4993-2,,10.1145/3110025.3120994,http://doi.acm.org/10.1145/3110025.3120994,,2017,13/11/2018 10:47,14/04/2020 08:34,,1172–1174,,,,,,,ASONAM '17,,,,ACM,"New York, NY, USA",,,,,,,,,,,,1; 110; cancer; care coordination; data collection; egocentric; lessons learned; measurement; patient; social network,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7M6ZHGGF,conferencePaper,2017,"Choudhury, Abhinav; Kaushik, Shruti; Dutt, Varun",Social-Network Analysis for Pain Medications: Influential Physicians May Not Be High-volume Prescribers,Proceedings of the 2017 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining 2017,978-1-4503-4993-2,,10.1145/3110025.3110113,http://doi.acm.org/10.1145/3110025.3110113,,2017,13/11/2018 10:47,14/04/2020 08:34,,881–885,,,,,,,ASONAM '17,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 110; eigenvector centrality; gender; pain medications; Social network analysis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WNZL6WAG,conferencePaper,2017,"Thiyagaraja, Shanti R.; Dantu, Ram; Shrestha, Pradhumna L.; Thompson, Mark A.; Smith, Christopher",Optimized and Secured Transmission and Retrieval of Vital Signs from Remote Devices,"Proceedings of the Second IEEE/ACM International Conference on Connected Health: Applications, Systems and Engineering Technologies",978-1-5090-4721-5,,10.1109/CHASE.2017.55,https://doi.org/10.1109/CHASE.2017.55,,2017,13/11/2018 10:47,14/04/2020 08:35,,25–30,,,,,,,CHASE '17,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100; cloud computing; mobile health; performance evaluation; security,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3V8PQ4BN,conferencePaper,2017,"Sorensen, Reed J. D.; Flaxman, Abraham D.; Deason, Alec; Mumford, John Everett; Eldrenkamp, Erika; Moses, Mark; Weaver, Marcia R.",Microsimulation Models for Cost-effectiveness Analysis: A Review and Introduction to CEAM,Proceedings of the Summer Simulation Multi-Conference,,,,http://dl.acm.org/citation.cfm?id=3140065.3140097,,2017,13/11/2018 10:47,14/04/2020 08:35,,32:1–32:11,,,,,,,SummerSim '17,,,,Society for Computer Simulation International,"San Diego, CA, USA",,,,,,,,,,,,00; 100; 120; cost-effectiveness; Markov model; microsimulation; python,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QJLY7JWJ,conferencePaper,2017,"Martinez-Maldonado, Roberto; Pechenizkiy, Mykola; Buckingham Shum, Simon; Power, Tamara; Hayes, Carolyn; Axisa, Carmen",Modelling Embodied Mobility Teamwork Strategies in a Simulation-Based Healthcare Classroom,"Proceedings of the 25th Conference on User Modeling, Adaptation and Personalization",978-1-4503-4635-1,,10.1145/3079628.3079697,http://doi.acm.org/10.1145/3079628.3079697,,2017,13/11/2018 10:47,14/04/2020 08:34,,308–312,,,,,,,UMAP '17,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100; collaboration; computer vision; group modelling; physical analytics; proximity data; simulation-based learning; teamwork,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 87GQ2APY,conferencePaper,2017,"Flaxman, Abraham D.; Deason, Alec W.; Dolgert, Andrew J.; Mumford, John Everett; Sorensen, Reed J. D.; Eldrenkamp, Erika; Vos, Theo; Foreman, Kyle; Mokdad, Ali H.; Weaver, Marcia R.",Untangling Uncertainty with Common Random Numbers: A Simulation Study,Proceedings of the Summer Simulation Multi-Conference,,,,http://dl.acm.org/citation.cfm?id=3140065.3140096,,2017,13/11/2018 10:47,14/04/2020 08:34,,31:1–31:12,,,,,,,SummerSim '17,,,,Society for Computer Simulation International,"San Diego, CA, USA",,,,,,,,,,,,00; 100; common random values; parameter uncertainty; stochastic uncertainty,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YR477KCC,conferencePaper,2017,"Pagán, Josué; Moya, José M.; Risco-Martín, José L.; Ayala, José L.",Advanced Migraine Prediction Simulation System,Proceedings of the Summer Simulation Multi-Conference,,,,http://dl.acm.org/citation.cfm?id=3140065.3140089,,2017,13/11/2018 10:47,14/04/2020 08:35,,24:1–24:12,,,,,,,SummerSim '17,,,,Society for Computer Simulation International,"San Diego, CA, USA",,,,,,,,,,,,00; 100; failure detector; migraine prediction; robust system,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YK4EKYTB,conferencePaper,2017,"Nisperos, Saturnina; Kakde, Sonali; McKenzie, Frederic",An Agent-based Simulation of the Impact of Yogic Breathing Adoption,Proceedings of the Summer Simulation Multi-Conference,,,,http://dl.acm.org/citation.cfm?id=3140065.3140102,,2017,13/11/2018 10:47,14/04/2020 08:35,,37:1–37:8,,,,,,,SummerSim '17,,,,Society for Computer Simulation International,"San Diego, CA, USA",,,,,,,,,,,,00; 100; agent-based model; cardiovascular disease; yogic breathing technique,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TZMR2T5I,conferencePaper,2017,"Klasnja, Predrag; Hekler, Eric B.; Korinek, Elizabeth V.; Harlow, John; Mishra, Sonali R.",Toward Usable Evidence: Optimizing Knowledge Accumulation in HCI Research on Health Behavior Change,Proceedings of the 2017 CHI Conference on Human Factors in Computing Systems,978-1-4503-4655-9,,10.1145/3025453.3026013,http://doi.acm.org/10.1145/3025453.3026013,"Over the last ten years, HCI researchers have introduced a range of novel ways to support health behavior change, from glanceable displays to sophisticated game dynamics. Yet, this research has not had as much impact as its originality warrants. A key reason for this is that common forms of evaluation used in HCI make it difficult to effectively accumulate-and use-knowledge across research projects. This paper proposes a strategy for HCI research on behavior change that retains the field's focus on novel technical contributions while enabling accumulation of evidence that can increase impact of individual research projects both in HCI and the broader behavior-change science. The core of this strategy is an emphasis on the discovery of causal effects of individual components of behavior-change technologies and the precise ways in which those effects vary with individual differences, design choices, and contexts in which those technologies are used.",2017,13/11/2018 10:47,14/04/2020 08:34,,3071–3082,,,,,,,CHI '17,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100; behavior change; evaluation methods; health informatics; user studies,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9CVK4CSV,conferencePaper,2017,"Liao, Siyu; Xiao, Jiehao; Xie, Yi; Gu, Feng",Towards Use of Electronic Health Records: Cancer Classification,Proceedings of the Symposium on Modeling and Simulation in Medicine,978-1-5108-3825-3,,,http://dl.acm.org/citation.cfm?id=3108760.3108764,,2017,13/11/2018 10:47,14/04/2020 08:34,,4:1–4:10,,,,,,,MSM '17,,,,Society for Computer Simulation International,"San Diego, CA, USA",,,,,,,,,,,,00; 100; cancer diagnosis; classification; electronic health records; medical; random forest,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, L5ESLU6Y,conferencePaper,2017,"Sbayou, Mariem; Bouanan, Youssef; Zacharewicz, Gregory; Ribault, Judicael; François, Julien",Devs Modelling and Simulation for Healthcare Process Application for Hospital Emergency Department,Proceedings of the 50th Annual Simulation Symposium,,,,http://dl.acm.org/citation.cfm?id=3106388.3106392,,2017,13/11/2018 10:47,14/04/2020 08:35,,4:1–4:12,,,,,,,ANSS '17,,,,Society for Computer Simulation International,"San Diego, CA, USA",,,,,,,,,,,,1; 110; distributed simulation; healthcare organizations; performance; quality services; workflow,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5HHC7JMN,conferencePaper,2017,"Pires, Higo; Abdelouahab, Zair; Lopes, Denivaldo; Santos, Mário",A Framework for Agent-based Intrusion Detection in Wireless Sensor Networks,"Proceedings of the Second International Conference on Internet of Things, Data and Cloud Computing",978-1-4503-4774-7,,10.1145/3018896.3056805,http://doi.acm.org/10.1145/3018896.3056805,,2017,13/11/2018 10:47,14/04/2020 08:35,,188:1–188:7,,,,,,,ICC '17,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100; detection; information security; intelligent agents; intrusion detection systems; misuse-based; wireless sensor networks,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GWZDHFH4,conferencePaper,2017,"Hu, Yao; Min, Lequan; Su, Yongmei; Kuang, Yang",Mathematical Analysis of an SIR Network Model with Imperfect Vaccination and Varying Size of Population,Proceedings of the 8th International Conference on Computer Modeling and Simulation,978-1-4503-4816-4,,10.1145/3036331.3036348,http://doi.acm.org/10.1145/3036331.3036348,"Epidemic Spreading is a major global health problem. Modeling epidemic spreading dynamics is important for understanding and controlling epidemic spreading, providing prevention strategies. This paper points out some flaws existing in the susceptibleinfected - susceptible (SIS) model proposed by Safan and Rihan, and proposes a modified susceptible-infected-recovered (SIR) model on homogenous networks. It is proved that if the basic reproduction number Rv of the model is less than one, then the infection-free equilibrium of the model is globally asymptotically stable. On the other hand, if Rv of the model is more than one, the endemic equilibrium of the model is globally asymptotically stable. This paper also numerically predicts the effect of vaccination ratio on the size of HBV infected mainland Chinese population",2017,13/11/2018 10:47,14/04/2020 08:34,,7–13,,,,,,,ICCMS '17,,,,ACM,"New York, NY, USA",,,,,,,,,,,,1; 100; birth and death rate; global stability; homogenous network; local stability; SIR model,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, SL8BBRXU,conferencePaper,2016,"Huynh, De-Thu; Nhat, Tran Quang; Van, Dong Doan",Energy Optimization in Wireless Body Area Network Based on ZigBee,Proceedings of the 2016 International Conference on Intelligent Information Processing,978-1-4503-4799-0,,10.1145/3028842.3028844,http://doi.acm.org/10.1145/3028842.3028844,,2016,13/11/2018 10:47,14/04/2020 08:34,,2:1–2:6,,,,,,,ICIIP '16,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100; energy consumption optimization; multi-patient monitoring system; wireless body area network; ZigBee,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MWEJPIGI,conferencePaper,2016,"Wong, Zoie Shui-Yee; Lit, Albert Chau-Hung; Leung, Sin-Yee; Tsui, Kwok-Leung; Chin, Kwai-Sang",A Discrete-event Simulation Study for Emergency Room Capacity Management in a Hong Kong Hospital,Proceedings of the 2016 Winter Simulation Conference,978-1-5090-4484-9,,,http://dl.acm.org/citation.cfm?id=3042094.3042341,"It is very common for patients to face a long journey after the first physician visit in many emergency service care models. This affects the service quality of accident and emergency departments (AEDs). In this study, we developed discrete-event simulation models to mimic the complex health service system of a 24-hour AED in Hong Kong. We assessed how changing the number of emergency department physicians or the patient journey influenced AED performance achievement, which was quantified as service achievements for patients (SAP). We observed that reducing the time spent on subsequent treatments (after the first physician visit) among semi-urgent patients was comparatively sensitive to improving the overall AED outcomes. There was an increase in mean service achievements from 69.29% to 79.30% (95% confidence intervals were 1.28% and 0.98%, respectively). The proposed model is helpful in making decisions about emergency resource planning when there is a sudden surge of emergency patients.",2016,13/11/2018 10:47,14/04/2020 08:34,,1970–1981,,,,,,,WSC '16,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,1; 310; discrete event simulation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BK2W2NGH,conferencePaper,2016,"Rutherford, Alexander R.; Ramadanović, Bojan; Ahrenberg, Lukas; Michelow, Warren; Marshall, Brandon D. L.; Small, Will; Deering, Kathleen; Montaner, Julio S. G.; Vasarhelyi, Krisztina",Control of an HIV Epidemic Among Injection Drug Users: Simulation Modeling on Complex Networks,Proceedings of the 2016 Winter Simulation Conference,978-1-5090-4484-9,,,http://dl.acm.org/citation.cfm?id=3042094.3042106,,2016,13/11/2018 10:47,14/04/2020 08:35,,23–37,,,,,,,WSC '16,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8AA6AC53,conferencePaper,2016,"Uhrmacher, Adelinde M.; Brailsford, Sally; Liu, Jason; Rabe, Markus; Tolk, Andreas",Reproducible Research in Discrete Event Simulation: A Must or Rather a Maybe?,Proceedings of the 2016 Winter Simulation Conference,,,,http://dl.acm.org/citation.cfm?id=3042250.3042264,,2016,13/11/2018 10:47,14/04/2020 08:35,,1301–1315,,,,,,,WSC '16,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,******To read; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EYIYA38I,conferencePaper,2016,"Arisha, Amr; Rashwan, Wael","Modeling of Healthcare Systems: Past, Current and Future Trends",Proceedings of the 2016 Winter Simulation Conference,978-1-5090-4484-9,,,http://dl.acm.org/citation.cfm?id=3042094.3042289,"Increasing demand for healthcare services, due to changes in demographic shifts and constraints in healthcare funding, make it harder to manage effective, sustainable healthcare systems. Many healthcare modeling exercises have been undertaken with the aim of supporting the decision-making process. This paper reviews all of the 456 articles published by the Winter Simulation Conference over the past 48 years (1967--2015) on the subject of modeling and healthcare system simulation, and analyzes the relative frequency of approaches used. A multi-dimensional taxonomy is applied to encompass the modeling techniques, problem applications and decision levels reported in the articles. One of the most significant changes in the modeling of healthcare systems is the fact that Discrete-event Simulation (DES) is no longer used as an autonomous method, but rather as an integral part of the solution. The mixed-methods, hybrid and multi-paradigm approaches feature strongly in the current direction of modeling in healthcare systems.",2016,13/11/2018 10:47,14/04/2020 08:34,,1523–1534,,,,,,,WSC '16,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100; 120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MQH4GV4M,conferencePaper,2016,"Rashwan, Wael; Habib, Heba; Arisha, Amr; Courtney, Garry; Kennelly, Sean",An Integrated Approach of Multi-objective Optimization Model for Evaluating New Supporting Program in Irish Hospitals,Proceedings of the 2016 Winter Simulation Conference,,,,http://dl.acm.org/citation.cfm?id=3042250.3042333,"Hospitals are witnessing an inexorable growth in emergency admissions, which results in overcrowding and a poorer patient experience. The Acute Medicine Program (AMP) is one of the programs developed by the Irish health authority aimed at improving patient experience. To review the AMP intervention, this study applies a model that integrates three analytical approaches: simulation, multivariate factor analysis and multi-objective optimization. The simulation identified 14 different factors affecting five responses that were used to develop a Design of Experiments (DoE). Multivariate factor analysis used the DoE to determine the factors creating 'bottlenecks', such as downstream resources. The multi-objective optimization model, based on the Simulated Annealing approach, is applied to support management decisions on optimizing key parameters affecting the treatment journey of patients. A Pareto set of solutions found that an increase in downstream capacity and unit staff can lead to a 25% decrease at least in the patient's experience time.",2016,13/11/2018 10:47,14/04/2020 08:35,,1904–1915,,,,,,,WSC '16,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7UMIK39S,conferencePaper,2016,"Matchar, David B.; Ansah, John. P.; Bayer, Steffen; Hovmand, Peter",Simulation Modeling for Primary Care Planning in Singapore,Proceedings of the 2016 Winter Simulation Conference,978-1-5090-4484-9,,,http://dl.acm.org/citation.cfm?id=3042094.3042359,"Singapore is undergoing an epidemiological shift and has to provide services for an aging population with a higher burden of chronic disease. In order to address this challenge, enhancing the provision of primary care by improving the ability of more primary care providers to offer care to more complex patients over the continuum of needs is seen as a promising solution. Developing capabilities and capacities of primary care services is far from straightforward and requires careful analysis of how increasing the number of primary care providers with enhanced capabilities influences the multiple objectives of the health care system. The paper demonstrates how group model building can be used to facilitate this planning process, and provides potentially valuable initial insights regarding the tradeoffs engendered by policies aimed at meeting the health care needs of a more complex population.",2016,13/11/2018 10:47,14/04/2020 08:34,,2123–2134,,,,,,,WSC '16,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,"

Winter Simulation Conference (WSC), Arlington, VA, DEC 11-14, 2016

",,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6WF2LYF2,conferencePaper,2016,"Díaz, Daniela Angulo; Akhavan-Tabatabaei, Raha; Mura, Ivan",A Compartmentalized Simulation Model for Evaluation of HPV Vaccination Policies in Colombia,Proceedings of the 2016 Winter Simulation Conference,978-1-5090-4484-9,,,http://dl.acm.org/citation.cfm?id=3042094.3042344,"Cervical cancer (CC) is the second leading cause of cancer-related deaths among Colombian women, caused most commonly by Human Papillomavirus (HPV) infection. Screening programs, vaccination against HPV and improved socio-economic conditions have significantly reduced CC mortality rate over the last 40 years. Understanding the transmission dynamics of HPV infection is essential to the definition of cost-effective disease control strategies. We propose a compartmentalized epidemiological simulation model based on differential equations, which represents HPV transmission within the population, likelihood of infection clearance, virus induced appearance of precancerous lesions and eventually of CC. Time-dependent birth and natural mortality rates inferred from census are used to calibrate model population dynamics. Literature data and 5-years medical records of 3,428 Colombian women are used to estimate the infection dynamics and cancerous stages. The model allows evaluating the predicted effects of vaccination strategies against HPV, providing valuable support to healthcare decision-makers.",2016,13/11/2018 10:47,14/04/2020 08:34,,1994–2005,,,,,,,WSC '16,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,1; Review,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MKPU99Y3,conferencePaper,2016,"Sundaram, Ravishankar; Rukmangadhan, Saranya",Optimizing Kitchen Experience,Proceedings of the 8th Indian Conference on Human Computer Interaction,978-1-4503-4863-8,,10.1145/3014362.3014380,http://doi.acm.org/10.1145/3014362.3014380,,2016,13/11/2018 10:47,14/04/2020 08:35,,147–156,,,,,,,IHCI '16,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100; Design for India; Human factors and ergonomics; Optimizing space utilization; Universal Design; User centric innovation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PELBBQZI,conferencePaper,2016,"Smith, Shaden; Park, Jongsoo; Karypis, George",An Exploration of Optimization Algorithms for High Performance Tensor Completion,"Proceedings of the International Conference for High Performance Computing, Networking, Storage and Analysis",978-1-4673-8815-3,,,http://dl.acm.org/citation.cfm?id=3014904.3014946,,2016,13/11/2018 10:47,14/04/2020 08:35,,31:1–31:13,,,,,,,SC '16,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XNHGQNXF,conferencePaper,2016,"Williams, Alishia D.",Harnessing the Quantified Self Movement for Optimal Mental Health and Wellbeing,Proceedings of the First Workshop on Lifelogging Tools and Applications,978-1-4503-4517-0,,10.1145/2983576.2983585,http://doi.acm.org/10.1145/2983576.2983585,,2016,13/11/2018 10:47,14/04/2020 08:35,,37–37,,,,,,,LTA '16,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 110; mental health; wearables; wellbeing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, K27XEA7T,journalArticle,2016,"Ribeiro, Mateus L.; Lederman, Henrique Manoel; Elias, Simone; Nunes, FÁtima L. S.",Techniques and Devices Used in Palpation Simulation with Haptic Feedback,ACM Comput. Surv.,,0360-0300,10.1145/2962723,http://doi.acm.org/10.1145/2962723,,2016-10,13/11/2018 10:47,14/04/2020 08:35,,48:1–48:28,,3,49,,,,,,,,,,,,,,,,,,,,,00; 100; force feedback; haptics; health simulation; Palpation exam; simulation; virtual reality,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RJXTXJJS,conferencePaper,2016,"de Monasterio, Juan; Salles, Alejo; Lang, Carolina; Weinberg, Diego; Minnoni, Martin; Travizano, Matias; Sarraute, Carlos",Analyzing the Spread of Chagas Disease with Mobile Phone Data,Proceedings of the 2016 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining,978-1-5090-2846-7,,,http://dl.acm.org/citation.cfm?id=3192424.3192538,,2016,13/11/2018 10:47,14/04/2020 08:34,,607–612,,,,,,,ASONAM '16,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, REKNTJWG,conferencePaper,2016,"You, Linlin; Tunçer, Bige",Exploring Public Sentiments for Livable Places Based on a Crowd-calibrated Sentiment Analysis Mechanism,Proceedings of the 2016 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining,978-1-5090-2846-7,,,http://dl.acm.org/citation.cfm?id=3192424.3192555,,2016,13/11/2018 10:47,14/04/2020 08:35,,693–700,,,,,,,ASONAM '16,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, T3NJPC3R,conferencePaper,2016,"Guo, Ruocheng; Shakarian, Paulo",A Comparison of Methods for Cascade Prediction,Proceedings of the 2016 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining,978-1-5090-2846-7,,,http://dl.acm.org/citation.cfm?id=3192424.3192536,,2016,13/11/2018 10:47,14/04/2020 08:34,,591–598,,,,,,,ASONAM '16,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, J8N6TMBP,conferencePaper,2016,"Dhouioui, Zeineb; Tlich, Helmi; Toujeni, Radhia; Akaichi, Jalel",A Fuzzy Model for Friendship Prediction in Healthcare Social Networks,Proceedings of the 2016 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining,978-1-5090-2846-7,,,http://dl.acm.org/citation.cfm?id=3192424.3192623,,2016,13/11/2018 10:47,14/04/2020 08:34,,1050–1054,,,,,,,ASONAM '16,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, P3RC2D3T,conferencePaper,2016,"Kumar, Nikhil; Guo, Ruocheng; Aleali, Ashkan; Shakarian, Paulo",An Empirical Evaluation of Social Influence Metrics,Proceedings of the 2016 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining,978-1-5090-2846-7,,,http://dl.acm.org/citation.cfm?id=3192424.3192665,,2016,13/11/2018 10:47,14/04/2020 08:34,,1329–1336,,,,,,,ASONAM '16,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EKK5GGBB,conferencePaper,2016,"McAndrew, Thomas C.; Bongard, Joshua C.; Danforth, Christopher M.; Dodds, Peter Sheridan; Hines, Paul D. H.; Bagrow, James P.",What We Write About when We Write About Causality: Features of Causal Statements Across Large-scale Social Discourse,Proceedings of the 2016 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining,978-1-5090-2846-7,,,http://dl.acm.org/citation.cfm?id=3192424.3192521,,2016,13/11/2018 10:47,14/04/2020 08:34,,519–524,,,,,,,ASONAM '16,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 110; causal attribution; natural language processing; online social network; social media,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XRYRF6YB,conferencePaper,2016,"Peng, Yang; Moh, Melody; Moh, Teng-Sheng",Efficient Adverse Drug Event Extraction Using Twitter Sentiment Analysis,Proceedings of the 2016 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining,978-1-5090-2846-7,,,http://dl.acm.org/citation.cfm?id=3192424.3192617,,2016,13/11/2018 10:47,14/04/2020 08:35,,1011–1018,,,,,,,ASONAM '16,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100; ADEs; data mining; machine learning; nature language processing; sentiment analysis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9PJAT2NR,conferencePaper,2016,"Zhang, Yuyu; Bahadori, Mohammad Taha; Su, Hang; Sun, Jimeng",FLASH: Fast Bayesian Optimization for Data Analytic Pipelines,Proceedings of the 22Nd ACM SIGKDD International Conference on Knowledge Discovery and Data Mining,978-1-4503-4232-2,,10.1145/2939672.2939829,http://doi.acm.org/10.1145/2939672.2939829,,2016,13/11/2018 10:47,14/04/2020 08:35,,2065–2074,,,,,,,KDD '16,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100; automated hyperparameter tuning; bayesian optimization; data analytic pipeline; health analytics,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HQMW97IW,journalArticle,2016,"Haddad, Hedi; Moulin, Bernard; Thériault, Marius",A Fully GIS-integrated Simulation Approach for Analyzing the Spread of Epidemics in Urban Areas,SIGSPATIAL Special,,1946-7729,10.1145/2961028.2961034,http://doi.acm.org/10.1145/2961028.2961034,,2016-06,13/11/2018 10:47,14/04/2020 08:34,,34–41,,1,8,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CTAIFWE7,conferencePaper,2016,"de Feijter, Dimph; Khan, Vassilis-Javed; van Gisbergen, Marnix",Confessions of A 'Guilty' Couch Potato Understanding and Using Context to Optimize Binge-watching Behavior,Proceedings of the ACM International Conference on Interactive Experiences for TV and Online Video,978-1-4503-4067-0,,10.1145/2932206.2932216,http://doi.acm.org/10.1145/2932206.2932216,,2016,13/11/2018 10:47,14/04/2020 08:34,,59–67,,,,,,,TVX '16,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100; binge-watching; context; health-implications; mobile survey; self-regulation; tv viewing behavior,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9M3TSX96,conferencePaper,2016,"Kristiansen, Stein; Plagemann, Thomas; Goebel, Vera",Smooth and Crispy: Integrating Continuous Event Proximity Calculation and Discrete Event Detection,Proceedings of the 10th ACM International Conference on Distributed and Event-based Systems,978-1-4503-4021-2,,10.1145/2933267.2933302,http://doi.acm.org/10.1145/2933267.2933302,,2016,13/11/2018 10:47,14/04/2020 08:34,,153–160,,,,,,,DEBS '16,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100; complex event processing; event proximity; home care,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UDWR3V9P,conferencePaper,2016,"Heshmat, M.; Eltawil, A.",A System Dynamics Model for Chemotherapy,Proceedings of the 10th International Conference on Informatics and Systems,978-1-4503-4062-5,,10.1145/2908446.2908461,http://doi.acm.org/10.1145/2908446.2908461,"Chemotherapy is one of the most common approaches in cancer treatment. The problem with chemotherapy is that it does not only kill the cancerous cells, but the therapy affects badly the healthy cells as well. Accumulation of chemotherapy drugs with repeated doses in the patient's body leads to increasing toxicity in the whole body. This paper develops a general system dynamics model which clarifies the different factors affecting the treatment plans such as number of cancerous cells, drug accumulation, and toxicity. A stock and flow diagram is constructed to show the interaction of the system variables with each other. A simulation model using iT hink software is used. The simulation results show a decreasing trend of the number of cancerous cells with repeated chemotherapy doses with time. On the other hand, the toxicity increases with time. Finally, sensitivity analysis is conducted to show the effect of doses cancellation and delay on the treatment efficacy. The results show that the model is more sensitive to doses cancellation than doses delay, thus cancelling doses is more critical on the patient's health than doses delaying.",2016,13/11/2018 10:47,14/04/2020 08:34,,7–13,,,,,,,INFOS '16,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 140; Chemotherapy; Simulation; Stock and Flow; System Dynamics,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ALMZDUS8,conferencePaper,2016,"Jones, Austin; Ali, Usman; Egerstedt, Magnus",Optimal Pesticide Scheduling in Precision Agriculture,Proceedings of the 7th International Conference on Cyber-Physical Systems,,,,http://dl.acm.org/citation.cfm?id=2984464.2984476,,2016,13/11/2018 10:47,14/04/2020 08:34,,12:1–12:8,,,,,,,ICCPS '16,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WFBIDCMG,journalArticle,2016,"Delabrida, Saul; D'Angelo, Thiago; Oliveira, Ricardo A.R.; Loureiro, Antonio A.F.",Building Wearables for Geology: An Operating System Approach,SIGOPS Oper. Syst. Rev.,,0163-5980,10.1145/2903267.2903275,http://doi.acm.org/10.1145/2903267.2903275,,2016-03,13/11/2018 10:47,14/04/2020 08:34,,31–45,,1,50,,,,,,,,,,,,,,,,,,,,,00; 100; Wearable Operating System; Wearable RTOS; Wearable User Interface OS,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EUQXP9XL,conferencePaper,2015,"Tsimeris, Jessica; Stevenson, Duncan; Broughton, Michael; Gedeon, Tom",Adapting a Soft 2.5D Actuated Shape Display for Rebound Tenderness Simulation and Training,Proceedings of the Annual Meeting of the Australian Special Interest Group for Computer Human Interaction,978-1-4503-3673-4,,10.1145/2838739.2838750,http://doi.acm.org/10.1145/2838739.2838750,,2015,13/11/2018 10:47,14/04/2020 08:35,,549–556,,,,,,,OzCHI '15,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100; Human Computer Interaction; Soft Interfaces; Tangible User Interfaces; User Evaluation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IUJ27FMJ,conferencePaper,2015,"Bruballa, Eva; Taboada, Manel; Wong, Alvaro; Rexachs, Dolores; Luque, Emilio",Evaluation of Performance and Response Capacity in Emergency Deparments,Proceedings of the 2015 Winter Simulation Conference,978-1-4673-9741-4,,,http://dl.acm.org/citation.cfm?id=2888619.2889055,"The saturation of Emergency Departments, due to the increasing demand of the service, is a current problem in the healthcare system. We propose an analytical model to obtain information from data obtained through the simulation of a Hospital Emergency Department. The model defines how to calculate the theoretical throughput of a particular sanitary staff configuration, that is, the number of patients it can attend per unit time given its composition. This index is a reference to measure indicators concerning to performance and emergency response capacity of the system. The data for the analysis will be generated by the simulation of any possible scenario of the real system, taking into account all valid sanitary staff configurations and different number of patients entering into the emergency service.",2015,13/11/2018 10:47,14/04/2020 08:34,,3228–3229,,,,,,,WSC '15,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UEV69PUX,conferencePaper,2015,"Miksch, Florian; Pichler, Philipp; Espinosa, Kurt J. P.; Casera, Katrina S. T.; Navarro, Aldrin N.; Bicher, Martin",An Agent-based Epidemic Model for Dengue Simulation in the Philippines,Proceedings of the 2015 Winter Simulation Conference,978-1-4673-9741-4,,,http://dl.acm.org/citation.cfm?id=2888619.2889041,,2015,13/11/2018 10:47,14/04/2020 08:34,,3202–3203,,,,,,,WSC '15,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KAA5INU5,conferencePaper,2015,"Levin, Scott; Garifullin, Maxim",Simulating Wait Time in Healthcare: Accounting for Transition Process Variability Using Survival Analyses,Proceedings of the 2015 Winter Simulation Conference,978-1-4673-9741-4,,,http://dl.acm.org/citation.cfm?id=2888619.2888759,"Wait or queuing time is a principal performance measure for many discrete-event simulation (DES) models in healthcare. However, variation in wait time is often caused by both occupied downstream servers (e.g., beds) and organizational and human transition processes. DES models that attribute wait solely to occupied servers, ignoring transition process variability, face challenges in adequate baseline validation. Embedding regression models for survival data in DES to estimate patient wait times is a method capable of integrating the effects of transition processes with queuing. Developing these models as a sub-component is further valuable in understanding the socio-technical system factors that drive prolonged waits. These general methods are exhibited in a DES for a large urban hospital with a primary output of wait time in the emergency department (ED) for transfer to an inpatient bed (boarding time). Simulated boarding time is compared before and after accounting for transition processes using survival analysis.",2015,13/11/2018 10:47,14/04/2020 08:34,,1252–1260,,,,,,,WSC '15,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,1; 420; Discrete Event,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EYK378FG,conferencePaper,2015,"Hicklin, Karen; Ivy, Julie S.; Wilson, James R.; Myers, Evan",Using Percentile Matching to Simulate Labor Progression and the Effect of Labor Duration on Birth Complications,Proceedings of the 2015 Winter Simulation Conference,978-1-4673-9741-4,,,http://dl.acm.org/citation.cfm?id=2888619.2888988,,2015,13/11/2018 10:47,14/04/2020 08:34,,3104–3105,,,,,,,WSC '15,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VMEEQY9X,conferencePaper,2015,"Zhang, Limao; AbouRizk, Simaan M.; Wu, Xianguo",How to Protect Adjacent Bridges Due to Tunnel Excavation: A Case Study,Proceedings of the 2015 Winter Simulation Conference,978-1-4673-9741-4,,,http://dl.acm.org/citation.cfm?id=2888619.2889060,,2015,13/11/2018 10:47,14/04/2020 08:35,,3246–3256,,,,,,,WSC '15,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BS6W7AI5,conferencePaper,2015,"Rizia, Rizwana; Franco, Zeno; Hooyer, Katinka; Johnson, Nadiyah; Patwary, A B M Kowser; Ahsan, Golam Mushih Tanimul; Curry, Bob; Flower, Mark; Ahamed, Sheikh Iqbal",iPeer: A Sociotechnical Systems Approach for Helping Veterans with Civilian Reintegration,Proceedings of the 2015 Annual Symposium on Computing for Development,978-1-4503-3490-7,,10.1145/2830629.2830643,http://doi.acm.org/10.1145/2830629.2830643,,2015,13/11/2018 10:47,14/04/2020 08:35,,85–93,,,,,,,DEV '15,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100; collaboration systems; electronic peer-mentorship; mobile computing; socio-technical systems; symptom monitoring; veteran mental healthcare,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, U4L8JCSM,conferencePaper,2015,"Winkler, Daniel A.; Wang, Robert; Blanchette, Francois; Carreira-Perpiñán, Miguel Á.; Cerpa, Alberto E.",Poster: MICO: Model-Based Irrigation Control Optimization,Proceedings of the 13th ACM Conference on Embedded Networked Sensor Systems,978-1-4503-3631-4,,10.1145/2809695.2817888,http://doi.acm.org/10.1145/2809695.2817888,,2015,13/11/2018 10:47,14/04/2020 08:35,,409–410,,,,,,,SenSys '15,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100; control; irrigation; monitoring,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, P9W7ANVZ,conferencePaper,2015,"Fuertes, Walter; Carrera, Diego; Villacís, César; Toulkeridis, Theofilos; Galárraga, Fernando; Torres, Edgar; Aules, Hernán","Distributed System As Internet of Things for a New Low-cost, Air Pollution Wireless Monitoring on Real Time",Proceedings of the 19th International Symposium on Distributed Simulation and Real Time Applications,978-1-4673-7822-2,,10.1109/DS-RT.2015.28,https://doi.org/10.1109/DS-RT.2015.28,,2015,13/11/2018 10:47,14/04/2020 08:34,,58–67,,,,,,,DS-RT 2015,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100; agile methodologies; air pollution; Arduino; distributed systems; electronic sensors; IoT; real time,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5G2AEZ2W,conferencePaper,2015,"Kaya, Buket; Poyraz, Mustafa",Finding Relations Between Diseases by Age-Series Based Supervised Link Prediction,Proceedings of the 2015 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining 2015,978-1-4503-3854-7,,10.1145/2808797.2808812,http://doi.acm.org/10.1145/2808797.2808812,,2015,13/11/2018 10:47,14/04/2020 08:34,,1097–1103,,,,,,,ASONAM '15,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 110; disease networks; health informatics; link prediction; supervised learning,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9WRAPHM3,conferencePaper,2015,"Phan, NhatHai; Dou, Dejing; Piniewski, Brigitte; Kil, David",Social Restricted Boltzmann Machine: Human Behavior Prediction in Health Social Networks,Proceedings of the 2015 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining 2015,978-1-4503-3854-7,,10.1145/2808797.2809307,http://doi.acm.org/10.1145/2808797.2809307,,2015,13/11/2018 10:47,14/04/2020 08:35,,424–431,,,,,,,ASONAM '15,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UPZJKTKK,conferencePaper,2015,"Tekieh, Mohammad Hossein; Raahemi, Bijan",Importance of Data Mining in Healthcare: A Survey,Proceedings of the 2015 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining 2015,978-1-4503-3854-7,,10.1145/2808797.2809367,http://doi.acm.org/10.1145/2808797.2809367,"In this survey, we collect the related information that demonstrate the importance of data mining in healthcare. As the amount of collected health data is increasing significantly every day, it is believed that a strong analysis tool that is capable of handling and analyzing large health data is essential. Analyzing the health datasets gathered by electronic health record (EHR) systems, insurance claims, health surveys, and other sources, using data mining techniques is very complex and is faced with very specific challenges, including data quality and privacy issues. However, the applications of data mining in healthcare, advantages of data mining techniques over traditional methods, special characteristics of health data, and new health condition mysteries have made data mining very necessary for health data analysis.",2015,13/11/2018 10:47,14/04/2020 08:35,,1057–1062,,,,,,,ASONAM '15,,,,ACM,"New York, NY, USA",,,,,,,,,,,,1; 110; data mining; data mining applications; data quality; health big data; health data analysis; predictive modelling,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YWCEEFHX,conferencePaper,2015,"Yesha, Rose; Gangopadhyay, Aryya; Siegel, Eliot",A Graph-Based Method for Analyzing Electronic Medical Records,Proceedings of the 2015 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining 2015,978-1-4503-3854-7,,10.1145/2808797.2808806,http://doi.acm.org/10.1145/2808797.2808806,"The recent years have seen a surge in the implementation of electronic health care records. These patient records contain valuable medical information including patient information, diagnosis, treatment methods, and eventual patient outcomes. It is important to analyze patterns within these records in order to more efficiently treat individuals. In this paper, we present a method for automatically discovering underlying themes and patterns within patient data. Our methodology includes the creation of the main themes or patterns in the data and linking the themes back to the corpus from which they were generated. In our research, we partitioned graphs from terms gathered from electronic health records. Modularity was used as the quality function, which strives to measure how well a given partition of a network compartmentalizes its communities. We have compared our method with probabilistic topic modeling algorithms, specifically LDA (Latent Dirichlet Allocation). Finally, recall and precision measures were used to evaluate the validity of our final results.",2015,13/11/2018 10:47,14/04/2020 08:35,,1036–1041,,,,,,,ASONAM '15,,,,ACM,"New York, NY, USA",,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GFUSSYLL,conferencePaper,2015,"Lee, Kathy; Agrawal, Ankit; Choudhary, Alok",Mining Social Media Streams to Improve Public Health Allergy Surveillance,Proceedings of the 2015 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining 2015,978-1-4503-3854-7,,10.1145/2808797.2808896,http://doi.acm.org/10.1145/2808797.2808896,"Allergies are one of the most common chronic diseases worldwide. One in five Americans suffer from either allergy or asthma symptoms. With the prevalence of social media, people sharing experiences and opinions on personal health symptoms and concerns on social media are increasing. Mining those publicly available health related data potentially provides valuable healthcare insights. In this paper, we propose a real-time allergy surveillance system that first classifies tweets to identify those that mention actual allergy incidents using bag-of-words model and NaiveBayesMultinomial classifier and applies in-depth text and spatiotemporal analysis. Our experimental results show that the proposed system can detect predominant allergy types with high precision and that allergy-related tweet volume is highly correlated to the weather data (daily maximum temperature). We believe that this is the first study that examines a large-scale social media stream for in-depth analysis of allergy activities.",2015,13/11/2018 10:47,14/04/2020 08:34,,815–822,,,,,,,ASONAM '15,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 110; Allergy; Public Health; Social Media; Twitter,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RRXHUPQN,conferencePaper,2015,"Azlah, Nada; Shareefdeen, Zarook; Elkamel, Ali; Madhuranthakam, ChandraMouli",Evaluation of Industrial Biofilter Emissions on Health Effects Through Dispersion Model Predictions,Proceedings of the Conference on Summer Computer Simulation,978-1-5108-1059-4,,,http://dl.acm.org/citation.cfm?id=2874916.2874942,,2015,13/11/2018 10:47,14/04/2020 08:34,,1–6,,,,,,,SummerSim '15,,,,Society for Computer Simulation International,"San Diego, CA, USA",,,,,,,,,,,,00; 100; air pollution; biofilter; CALPUFF; dispersion; health effects,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XCYMQYSM,conferencePaper,2015,"Scholz, Stefan; Batram, Manuel; Greiner, Wolfgang",The SILAS Model: Sexual Infections As Large-scale Agent-based Simulation,Proceedings of the Conference on Summer Computer Simulation,978-1-5108-1059-4,,,http://dl.acm.org/citation.cfm?id=2874916.2874970,,2015,13/11/2018 10:47,14/04/2020 08:35,,1–6,,,,,,,SummerSim '15,,,,Society for Computer Simulation International,"San Diego, CA, USA",,,,,,,,,,,,00; 100; agent-based model; demographics; epidemiology; sexually transmitted infections,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NJ9T8M5N,conferencePaper,2015,"Rosen, Scott L.; Ramsey, Jim; Harvey, Christine E.; Guharay, Samar K.",Efficient Analysis for Emergency Management Using Simulation Metamodeling: A Case Study for a Medical Trauma Center,Proceedings of the Conference on Summer Computer Simulation,978-1-5108-1059-4,,,http://dl.acm.org/citation.cfm?id=2874916.2874918,"This paper presents a rapid, quantitative simulation-based approach for Systems Engineering applicable to the emergency management domain. The motivation behind this approach is to provide improved decision-support for emergencies. A case study is performed on a problem in the healthcare domain concerning the effect of worker capacities in a trauma center. The application of simulation to healthcare systems analysis is a growing area, but analysis with large-scale simulations can be inefficient due to their long run times. This problem can be overcome by simulation metamodeling that provides the ability to expedite system evaluations and enable complex systems analysis. This paper demonstrates the effectiveness of simulation metamodeling for healthcare systems analysis. The methodology developed for this case study has the potential to be transferred or applied to other scenarios for emergency management.",2015,13/11/2018 10:47,14/04/2020 08:34,,1–8,,,,,,,SummerSim '15,,,,Society for Computer Simulation International,"San Diego, CA, USA",,,,,,,,,,,,1; 320; healthcare; pareto analysis; simulation metamodeling,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RSVS8U8I,conferencePaper,2015,"Zhang, Mingxin; Meng, Rongqing; Verbraeck, Alexander",Including Public Transportation into a Large-scale Agent-based Model for Epidemic Prediction and Control,Proceedings of the Conference on Summer Computer Simulation,978-1-5108-1059-4,,,http://dl.acm.org/citation.cfm?id=2874916.2874948,,2015,13/11/2018 10:47,14/04/2020 08:35,,1–8,,,,,,,SummerSim '15,,,,Society for Computer Simulation International,"San Diego, CA, USA",,,,,,,,,,,,00; 100; activity pattern; epidemic model; graph theory; openstreet map; public transportation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, W8RALHCR,conferencePaper,2015,"Baldominos, Alejandro; Saez, Yago; Isasi, Pedro",Feature Set Optimization for Physical Activity Recognition Using Genetic Algorithms,Proceedings of the Companion Publication of the 2015 Annual Conference on Genetic and Evolutionary Computation,978-1-4503-3488-4,,10.1145/2739482.2768506,http://doi.acm.org/10.1145/2739482.2768506,,2015,13/11/2018 10:47,14/04/2020 08:34,,1311–1318,,,,,,,GECCO Companion '15,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100; activity recognition; activity recognition chain; classification; feature selection; genetic algorithms; physical activity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, SVBGSQDC,journalArticle,2015,"Lotfi, Atieh; Rahimi, Abbas; Benini, Luca; Gupta, Rajesh K.",Aging-Aware Compilation for GP-GPUs,ACM Trans. Archit. Code Optim.,,1544-3566,10.1145/2778984,http://doi.acm.org/10.1145/2778984,,2015-07,13/11/2018 10:47,14/04/2020 08:34,,24:1–24:20,,2,12,,,,,,,,,,,,,,,,,,,,,00; 100; adaptive kernel; aging-aware compilation; GP-GPUs; NBTI; VLIW,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FBFP5UIA,conferencePaper,2015,"Allouche, Yair; Cassuto, Yuval; Efrat, Alon; Segal, Michael; Arkin, Esther M.; Grebla, Guy; Mitchell, Joseph S.B.; Sankararaman, Swaminathan",Secure Communication Through Jammers Jointly Optimized in Geography and Time,Proceedings of the 16th ACM International Symposium on Mobile Ad Hoc Networking and Computing,978-1-4503-3489-1,,10.1145/2746285.2746322,http://doi.acm.org/10.1145/2746285.2746322,,2015,13/11/2018 10:47,14/04/2020 08:34,,227–236,,,,,,,MobiHoc '15,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100; friendly jammers; optimization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GDBTUERH,conferencePaper,2015,"Rana, Ela; Giabbanelli, Philippe J.; Balabhadrapathruni, Naga H.; Li, Xiaoyu; Mago, Vijay K.",Exploring the Relationship Between Adherence to Treatment and Viral Load Through a New Discrete Simulation Model of HIV Infectivity,Proceedings of the 3rd ACM SIGSIM Conference on Principles of Advanced Discrete Simulation,978-1-4503-3583-6,,10.1145/2769458.2769477,http://doi.acm.org/10.1145/2769458.2769477,,2015,13/11/2018 10:47,14/04/2020 08:35,,145–156,,,,,,,SIGSIM PADS '15,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100; antiretroviral therapy; cellular automata; discrete simulation; hiv,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, G7DD85IJ,conferencePaper,2015,"Cui, Tiansong; Wang, Yanzhi; Chen, Shuang; Zhu, Qi; Nazarian, Shahin; Pedram, Massoud",Optimal Control of PEVs for Energy Cost Minimization and Frequency Regulation in the Smart Grid Accounting for Battery State-of-health Degradation,Proceedings of the 52Nd Annual Design Automation Conference,978-1-4503-3520-1,,10.1145/2744769.2744882,http://doi.acm.org/10.1145/2744769.2744882,,2015,13/11/2018 10:47,14/04/2020 08:34,,134:1–134:6,,,,,,,DAC '15,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HIZR8F6Y,conferencePaper,2015,"Uebelherr, Joshua M.; Hondula, David M.; Johnston, Erik W.",Innovative Participatory Agent Based Modeling Using a Complexity Governance Perspective,Proceedings of the 16th Annual International Conference on Digital Government Research,978-1-4503-3600-0,,10.1145/2757401.2757447,http://doi.acm.org/10.1145/2757401.2757447,"Increasing extreme heat mortality and morbidity is anticipated to increase with climate change and urbanization over the next century. The southwest U.S. in particular shows regional climate forecasts with hotter and drier conditions. There is notable heat related mortality and morbidity each year in the greater Phoenix, Arizona area of Maricopa County. This is despite efforts of many public and nonprofit organizations to minimize health risks associated with the region's persistent high temperatures. Access to air conditioned space has been shown to reduce heat related mortality risk. Cooling centers were established in during 2006 in the Phoenix area through the Heat Relief Network (HRN) as an intervention. The HRN is a group of voluntary public and nonprofit community organizations operating in partnership with the Maricopa Association of Governments as well as County and State public health agencies. Participatory modeling was used to engage the heat relief community in greater Phoenix using a Netlogo prototype agent based model of the 2013 HRN cooling centers. Such an approach affords new ways of incorporating local expertise experienced in the field as a means of translating evidence into practice and allows exploration cooling center network dynamics from a complexity governance perspective. Important lessons learned were often related to increased systemic awareness of opportunities to increase coordination through the heat relief network. For example leveraging self-organization through communication may help more evenly distribute limited resources, such as water bottle donations. Such lessons may provide insight to future challenges for cities around the world as extreme temperatures become more frequent and intense due to climate change and urbanization.",2015,13/11/2018 10:47,14/04/2020 08:35,,307–308,,,,,,,dg.o '15,,,,ACM,"New York, NY, USA",,,,,,,,,,,,1; 110; agent based modeling; complexity governance; heat mortality risk; participatory modeling; public health,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, B4AG58UA,conferencePaper,2015,"Pacciani, Eleonora; Borri, Alessandro; Soave, Paolo Maurizio; Gui, Daniele; Magalini, Sabina; Panunzi, Simona; Gaz, Claudio Roberto; Gaudio, Pasquale; Malizia, Andrea; De Gaetano, Andrea",Modelling and Simulation for Major Incidents: An Innovative Approach to Medical Response,Proceedings of the 9th International Conference on Pervasive Computing Technologies for Healthcare,978-1-63190-045-7,,,http://dl.acm.org/citation.cfm?id=2826165.2826223,"In recent years, there has been a rise in Major Incidents with big impact on the citizens health and the society. Without the possibility of conducting live experiments when it comes to physical and/or toxic trauma, only an accurate in silico reconstruction allows us to identify organizational solutions with the best possible chance of success, in correlation with the limitations on available resources (e.g. medical team, first responders, treatments, transports, and hospitals availability) and with the variability of the characteristic of event (e.g. type of incident, severity of the event and type of lesions). Utilizing modelling and simulation techniques, a simplified mathematical model of physiological evolution for patients involved in physical and toxic trauma incident scenarios has been developed and implemented. The model formalizes the dynamics, operating standards and practices of medical response and the main emergency service in the chain of emergency management during a Major Incident.",2015,13/11/2018 10:47,14/04/2020 08:35,,297–303,,,,,,,PervasiveHealth '15,,,,"ICST (Institute for Computer Sciences, Social-Informatics and Telecommunications Engineering)","ICST, Brussels, Belgium, Belgium",,,,,,,,,,,,00; 100; health monitoring applications; personalized patient treatment; predictive models for adverse outcomes,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KDS3QALV,conferencePaper,2015,"Kang, Yilin; Tan, Ah-Hwee",MAP: A Computational Model for Adaptive Persuasion,Proceedings of the 2015 International Conference on Autonomous Agents and Multiagent Systems,978-1-4503-3413-6,,,http://dl.acm.org/citation.cfm?id=2772879.2773479,,2015,13/11/2018 10:47,14/04/2020 08:34,,1871–1872,,,,,,,AAMAS '15,,,,International Foundation for Autonomous Agents and Multiagent Systems,"Richland, SC",,,,,,,,,,,,00; 100; adaptive; agent; persuasion; social behavior,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, J3N3KJER,conferencePaper,2015,"Rozenblit, Jerzy; Sametinger, Johannes",Models in Healthcare Simulation: Typology and Security Issues,Proceedings of the Symposium on Modeling and Simulation in Medicine,978-1-5108-0102-8,,,http://dl.acm.org/citation.cfm?id=2873003.2873008,,2015,13/11/2018 10:47,14/04/2020 08:35,,31–35,,,,,,,MSM '15,,,,Society for Computer Simulation International,"San Diego, CA, USA",,,,,,,,,,,,00; 100; healthcare; life-critical systems; models in medicine; security; simulation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QKNY8G6A,conferencePaper,2015,"Working Group, Population Modeling",Population Modeling by Examples (WIP),Proceedings of the Symposium on Modeling and Simulation in Medicine,978-1-5108-0102-8,,,http://dl.acm.org/citation.cfm?id=2873003.2887741,"The recent increase interest in population modeling has brought up the need to define the term. Rather than a formal definition, we are collectively defining the term by population modeling examples collected from all the authors. Examples include epidemiology, behavior, health economics, emergency response, biology, and computational tools. A formal definition is also discussed to provide a current definition for an emerging field.",2015,13/11/2018 10:47,14/04/2020 08:35,,61–66,,,,,,,MSM '15,,,,Society for Computer Simulation International,"San Diego, CA, USA",,,,,,,,,,,,1; 100; Definition; Multi Disciplinary; Population Modeling,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GYT2VFCH,conferencePaper,2015,"Abbas, Ismail",Simulating the Expected Net Benefits of Health Research: The Case of Randomized Clinical Trials for Comparing the Effects of Two Health Interventions,Proceedings of the Symposium on Modeling and Simulation in Medicine,978-1-5108-0102-8,,,http://dl.acm.org/citation.cfm?id=2873003.2873006,"Introduction: This paper presents a simulation model addressing whether from private and public perspectives it would be worthwhile to conduct clinical trials, considering the expected net benefit for the health system. Methods: Considering a clinical trial for evaluating two health interventions, the overall expected net benefits model is evaluated through two approaches: clinical trial and population simulation. The probability of standardized expected net benefits can be predicted to aid decision making under a variety of reasonable settings. Results: Two decisions can be made assuming the new intervention is dominant from a cost-effectiveness perspective. 1) As the null hypothesis can be rejected when it is true and the probability of expected net benefits increases beyond the minimal value of willingness to pay, conducting the trial is worthwhile from public health perspective. 2) As the null hypothesis can be rejected when there is a minimal difference and the probability of expected net benefits increases beyond the corresponding willingness to pay, conducting the trial is advisable from private health perspective. Discussion: Simulation modelling predicts valuable information supporting private and public health researchers and decision makers of clinical trials. Future research would extend the model to multi-center multi-stages clinical trials.",2015,13/11/2018 10:47,14/04/2020 08:34,,16–24,,,,,,,MSM '15,,,,Society for Computer Simulation International,"San Diego, CA, USA",,,,,,,,,,,,1; 100; expected net benefits; probability and statistics; randomized clinical trials; sensitivity analyses,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NNDS8YFJ,conferencePaper,2015,"Eswaran, Hari; Lowery, Curtis L.; McVay, B. C.; Dollins, C.; Lenin, R. B.",Reducing Length of Stay of Patients in an Outpatient OB Clinic: A Simulation Approach,Proceedings of the Symposium on Modeling and Simulation in Medicine,978-1-5108-0102-8,,,http://dl.acm.org/citation.cfm?id=2873003.2873004,"In the health care industry, a pressing issue is the need to assess and analyze care services in order to ensure efficient and quality care. For outpatient clinics, length of stay of patients is an important performance measure in helping to determine service quality. The Community Women's Clinic associated with the University of Arkansas for Medical Science is a practice dedicated to providing outpatient obstetrics care including high risk pregnancy. In this study, we develop an appointment template driven simulation model of the clinic, validate the model, and run several ""what-if"" scenarios to identify optimal number of staff to minimize the length of stay of patients in the clinic. The best scenario of adding one advanced practice nurse, one patient care technician, and one additional capacity in the non-stress test room improved the length of stay of patients for the entire clinic by 19% and for the high risk patients by 10%. We achieved these improvements without affecting the actual clinic activities which the clinic management had difficulty in achieving through many manual interventions.",2015,13/11/2018 10:47,14/04/2020 08:34,,1–8,,,,,,,MSM '15,,,,Society for Computer Simulation International,"San Diego, CA, USA",,,,,,,,,,,,EPIC data; Holt-Winters method; Review; utilization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BWM4MCYC,journalArticle,2015,"Gayathri, K. S.; Elias, Susan; Ravindran, Balaraman",Hierarchical Activity Recognition for Dementia Care Using Markov Logic Network,Personal Ubiquitous Comput.,,1617-4909,10.1007/s00779-014-0827-7,http://dx.doi.org/10.1007/s00779-014-0827-7,,2015-02,13/11/2018 10:47,14/04/2020 08:34,,271–285,,2,19,,,,,,,,,,,,,,,,,,,,,00; 100; Abnormality detection; Activity recognition; Dementia care; Hierarchical activity recognition; Hybrid approach; Markov Logic Network; Smart environment,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XQM3PGR9,conferencePaper,2014,"Mayorga, Maria E.; Reifsnider, Odette S.; Wheeler, Stephanie B.; Kohler, Racquel E.",A Discrete Event Simulation Model to Estimate Population Level Health and Economic Impacts of Smoking Cessation Interventions,Proceedings of the 2014 Winter Simulation Conference,,,,http://dl.acm.org/citation.cfm?id=2693848.2694011,"We design and develop a predictive model that estimates health and economic outcomes associated with smoking cessation interventions using discrete-event simulation (DES). Outcomes include estimates of sustained abstinence from smoking, quality of life years gained, cost of treatment, additional health-related morbidity due to long-term effects of smoking (e.g. lung cancer, stroke), and cost-effectiveness of the various smoking cessation options. Interventions assessed include nicotine replacement therapy (patch or gum,), oral medication (bupropion and varenicline), and abstinence without pharmacologic assistance. The DES approach allows us to account for heterogeneity of patients and dynamic changes in disease progression. Results show that even a single quit attempt can be cost-effective over the patients' lifetime. Furthermore, based on the incremental cost-effectiveness ratios, varenicline dominates other treatments at 10 years, 30 years, and over the lifetime. Understanding the comparative effectiveness and cost of alternative smoking cessation strategies can improve clinical and patient decision-making.",2014,13/11/2018 10:47,14/04/2020 08:34,,1257–1268,,,,,,,WSC '14,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,1; 220; Discrete Event; Population health,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ZG2I33EY,conferencePaper,2014,"Fakhimi, Masoud; Anagnostou, Anastasia; Stergioulas, Lampros; Taylor, Simon J. E.",A Hybrid Agent-based and Discrete Event Simulation Approach for Sustainable Strategic Planning and Simulation Analytics,Proceedings of the 2014 Winter Simulation Conference,,,,http://dl.acm.org/citation.cfm?id=2693848.2694049,"Modern healthcare reforms are required to be financially, environmentally and socially sustainable in order to address the additional constraints of financial resources shrinkage, pressure to reduce the environmental impacts and demand for improving the quality of healthcare services. Decision makers face the challenge of balancing all three aspects when planning. However, implementing such an approach, particularly in healthcare, is not a trivial task. Modeling & simulation is a valuable tool for studying complex systems. This paper investigates the application of a hybrid approach that combines Agent-based Modeling & Simulation (ABMS) and Discrete-Event Simulation (DES) for analyzing sustainable planning strategies for Emergency Medical Services. The paper presents a case study that shows how combined ABMS and DES models can support strategic planning and simulation analytics, respectively. The generated data from the ABMS is fed to the DES model in order to analyze the different strategies and the preliminary results are promising.",2014,13/11/2018 10:47,14/04/2020 08:34,,1573–1584,,,,,,,WSC '14,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,1; 320; hybrid simulation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 423C6QT5,conferencePaper,2014,"Balaban, Mariusz",Return to Work Behavior of People with Disabilities: A Multi-method Approach,Proceedings of the 2014 Winter Simulation Conference,,,,http://dl.acm.org/citation.cfm?id=2694013.2694047,,2014,13/11/2018 10:47,14/04/2020 08:34,,1561–1572,,,,,,,WSC '14,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VZEJBZMC,conferencePaper,2014,"Song, Eunhye; Nelson, Barry L.; Pegden, C. Dennis",Input Uncertainty Quantification: Advanced Tutorial,Proceedings of the 2014 Winter Simulation Conference,,,,http://dl.acm.org/citation.cfm?id=2693848.2693880,,2014,13/11/2018 10:47,14/04/2020 08:35,,162–176,,,,,,,WSC '14,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, F7UMPRJT,conferencePaper,2014,"Osgood, Nathaniel; Liu, Juxin",Towards Closed Loop Modeling: Evaluatng the Prospects for Creating Recurrently Regrounded Aggregate Simulation Models Using Particle Filtering,Proceedings of the 2014 Winter Simulation Conference,,,,http://dl.acm.org/citation.cfm?id=2693848.2693959,,2014,13/11/2018 10:47,14/04/2020 08:35,,829–841,,,,,,,WSC '14,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 25YQCU3Y,conferencePaper,2014,"Özaltin, Osman Y.; Dalgıç, Özden O.; Erenay, Fatih S.",Optimal Distribution of the Influenza Vaccine,Proceedings of the 2014 Winter Simulation Conference,,,,http://dl.acm.org/citation.cfm?id=2694013.2694029,"Influenza is a serious public health concern and vaccination is the first line of defense. In a pandemic, individuals are prioritized based on their risk profiles and transmission rates to ensure effective use of the available vaccine. We use an agent-based stochastic simulation model, and optimize the age-specific vaccine distribution strategy. We use black-box optimization techniques to minimize the overall cost of the outbreak. Our numerical experiments show that the best policy returned by our approach outperforms alternative policies recommended by the Advisory Committee on Immunization Practices and Centers for Disease Control and Prevention.",2014,13/11/2018 10:47,14/04/2020 08:34,,1411–1420,,,,,,,WSC '14,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,1; 310; Agent Based,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JTTUTPR9,conferencePaper,2014,"Taylor, Simon J. E.; Abbott, Pamela; Young, Terry; Grocott-Mason, Richard",Student Modeling & Simulation Projects in Healthcare: Experiences with Hillingdon Hospital,Proceedings of the 2014 Winter Simulation Conference,,,,http://dl.acm.org/citation.cfm?id=2693848.2694303,,2014,13/11/2018 10:47,14/04/2020 08:35,,3650–3661,,,,,,,WSC '14,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GTMUUBF9,conferencePaper,2014,"Pinto, Luiz Ricardo; Perpétuo, Ignez Helena Oliva; de Campos, Francisco Carlos Cardoso; Ribeiro, Yara Cristina Neves Marques Barbosa",Analisys of Hospital Bed Capacity via Queuing Theory and Simulation,Proceedings of the 2014 Winter Simulation Conference,,,,http://dl.acm.org/citation.cfm?id=2693848.2694015,,2014,13/11/2018 10:47,14/04/2020 08:35,,1281–1292,,,,,,,WSC '14,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QXYC5G3M,conferencePaper,2014,"Bhaduri, Budhendra L.; Bright, Edward A.; Rose, Amy N.; Liu, Cheng; Urban, Marie L.; Stewart, Robert N.",Data Driven Approach for High Resolution Population Distribution and Dynamics Models,Proceedings of the 2014 Winter Simulation Conference,,,,http://dl.acm.org/citation.cfm?id=2693848.2693961,,2014,13/11/2018 10:47,14/04/2020 08:34,,842–850,,,,,,,WSC '14,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GWD2DAEA,conferencePaper,2014,"Macal, Charles; North, Michael",Introductory Tutorial: Agent-based Modeling and Simulation,Proceedings of the 2014 Winter Simulation Conference,,,,http://dl.acm.org/citation.cfm?id=2693848.2693856,,2014,13/11/2018 10:47,14/04/2020 08:34,,6–20,,,,,,,WSC '14,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, AB2VKV2U,conferencePaper,2014,"Gogi, Anastasia; Tako, Antuela A.; Robinson, Stewart",A Preliminary Study on the Role of Simulation Models in Generating Insights,Proceedings of the 2014 Winter Simulation Conference,,,,http://dl.acm.org/citation.cfm?id=2693848.2694299,,2014,13/11/2018 10:47,14/04/2020 08:34,,3618–3629,,,,,,,WSC '14,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 55CAKG87,conferencePaper,2014,"Agrawal, Dharma P.",Magic of Wireless Sensor Networks,"Proceedings of the 17th ACM International Conference on Modeling, Analysis and Simulation of Wireless and Mobile Systems",978-1-4503-3030-5,,10.1145/2641798.2660247,http://doi.acm.org/10.1145/2641798.2660247,,2014,13/11/2018 10:47,14/04/2020 08:34,,117–118,,,,,,,MSWiM '14,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100; networking; wireless communications; wireless sensor networks,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KMARLD6J,conferencePaper,2014,"Liu, Chuanren; Ge, Yong; Xiong, Hui; Xiao, Keli; Geng, Wei; Perkins, Matt",Proactive Workflow Modeling by Stochastic Processes with Application to Healthcare Operation and Management,Proceedings of the 20th ACM SIGKDD International Conference on Knowledge Discovery and Data Mining,978-1-4503-2956-9,,10.1145/2623330.2623363,http://doi.acm.org/10.1145/2623330.2623363,"Advances in real-time location system (RTLS) solutions have enabled us to collect massive amounts of fine-grained semantically rich location traces, which provide unparalleled opportunities for understanding human activities and discovering useful knowledge. This, in turn, delivers intelligence for real-time decision making in various fields, such as workflow management. Indeed, it is a new paradigm for workflow modeling by the knowledge discovery in location traces. To that end, in this paper, we provide a focused study of workflow modeling by the integrated analysis of indoor location traces in the hospital environment. In comparison with conventional workflow modeling based on passive workflow logs, one salient feature of our approach is that it can proactively unravel the workflow patterns hidden in the location traces, by automatically constructing the workflow states and estimating parameters describing the transition patterns of moving objects. Specifically, to determine a meaningful granularity for the model, the workflow states are first constructed as regions associated with specific healthcare activities. Then, we transform the original indoor location traces to the sequences of workflow states and model the workflow transition patterns by finite state machines. Furthermore, we leverage the correlations in the location traces between related types of medical devices to reinforce the modeling performance and enable more applications. The results show that the proposed framework can not only model the workflow patterns effectively, but also have managerial applications in workflow monitoring, auditing, and inspection of workflow compliance, which are critical in the healthcare industry.",2014,13/11/2018 10:47,14/04/2020 08:34,,1593–1602,,,,,,,KDD '14,,,,ACM,"New York, NY, USA",,,,,,,,,,,,1; 110; healthcare operation and management; indoor location traces; workflow modeling,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, X7DCQERF,journalArticle,2014,"Yang, Jung-Gi; Kim, Jae-Kwon; Kang, Un-Gu; Lee, Young-Ho",Coronary Heart Disease Optimization System on Adaptive-network-based Fuzzy Inference System and Linear Discriminant Analysis (ANFIS—LDA),Personal Ubiquitous Comput.,,1617-4909,10.1007/s00779-013-0737-0,http://dx.doi.org/10.1007/s00779-013-0737-0,,2014-08,13/11/2018 10:47,14/04/2020 08:35,,1351–1362,,6,18,,,,,,,,,,,,,,,,,,,,,00; 100; Adaptive-network-based fuzzy inference system (ANFIS); Clinical decision support system (CDSS); Coronary heart disease (CHD); Data mining; Linear discriminant analysis (LDA),,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, I2PLKWU4,conferencePaper,2014,"Vicente, Sandra; Martin, Daniel; Vicente, Oliver; Doblas, Manuel; Maynar, Manuel",Reverse Logistic on Health,Proceedings of the 2014 Summer Simulation Multiconference,,,,http://dl.acm.org/citation.cfm?id=2685617.2685676,,2014,13/11/2018 10:47,14/04/2020 08:35,,59:1–59:7,,,,,,,SummerSim '14,,,,Society for Computer Simulation International,"San Diego, CA, USA",,,,,,,,,,,,00; 100; big data health; cognitive computer system; mobility agent; reverse logistic,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8YF5EXRP,conferencePaper,2014,"Mniszewski, S. M.; Manore, C. A.; Bryan, C.; Del Valle, S. Y.; Roberts, D.",Towards a Hybrid Agent-based Model for Mosquito Borne Disease,Proceedings of the 2014 Summer Simulation Multiconference,,,,http://dl.acm.org/citation.cfm?id=2685617.2685627,,2014,13/11/2018 10:47,14/04/2020 08:34,,10:1–10:8,,,,,,,SummerSim '14,,,,Society for Computer Simulation International,"San Diego, CA, USA",,,,,,,,,,,,00; 100; agent-based modeling; discrete event simulation; epidemic modeling; mathematical modeling; mosquito borne disease modeling,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DD9VDVBS,conferencePaper,2014,"McCormack, Paul; Chen, Tzu-Yi",Optimizing Leader Proportion and Behavior for Evacuating Buildings,Proceedings of the 2014 Symposium on Agent Directed Simulation,,,,http://dl.acm.org/citation.cfm?id=2665049.2665062,,2014,13/11/2018 10:47,14/04/2020 08:34,,13:1–13:6,,,,,,,ADS '14,,,,Society for Computer Simulation International,"San Diego, CA, USA",,,,,,,,,,,,100; agent-based simulation; crowd behavior; Helbing social force model; leader behavior; leader proportion; optimizing building evacuations,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, N9CXK5BR,conferencePaper,2014,"Shenvi, Ajit Ashok",Navigating the Maze: Journey Towards an Optimal Process Framework for Regulated Medical Software,Proceedings of the 7th India Software Engineering Conference,978-1-4503-2776-3,,10.1145/2590748.2590769,http://doi.acm.org/10.1145/2590748.2590769,,2014,13/11/2018 10:47,14/04/2020 08:35,,21:1–21:6,,,,,,,ISEC '14,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100; CMMI®; Compliance; ISO; medical device; quality management system; regulations,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4N4GTDVW,conferencePaper,2014,"Heitz, Alexandre; Dünser, Andreas; Bartneck, Christoph; Grady, Jonathan; Moran, Catherine",Assessing the Impact of a Clinical Audiology Simulator on First Year Students,Proceedings of the Fifteenth Australasian User Interface Conference - Volume 150,978-1-921770-33-3,,,http://dl.acm.org/citation.cfm?id=2667657.2667659,,2014,13/11/2018 10:47,14/04/2020 08:34,,11–20,,,,,,,AUIC '14,,,,"Australian Computer Society, Inc.","Darlinghurst, Australia, Australia",,,,,,,,,,,,00; 110; audiology; clinical education; computer simulation; virtual patient,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, I9VXWHCI,conferencePaper,2013,"Jimenez, Jose Mauricio; Lewis, Bryan Leroy; Eubank, Stephen",The Application of Macroergonomics and Simulation to Improve Control of Healthcare Acquired Infections,Proceedings of the 2013 Winter Simulation Conference: Simulation: Making Decisions in a Complex World,,,,http://dl.acm.org/citation.cfm?id=2675807.2675911,"We conducted a multidisciplinary study of healthcare acquired infections combining public health, simulation, and sociotechnical systems methods. Healthcare acquired infections (HAIs) represent a burden to the healthcare system due to the increased morbidity and mortality they cause on patients. Additionally, the cost of treating HAIs has increased dramatically in an already resource-strained healthcare system. We collected electronic medical records for the entire patient population of a level 1 trauma hospital for the period of one year. We additionally followed healthcare workers through their regular shifts to develop an accurate schedule of daily activities. Our team developed a simulation following the principles of highly-detailed simulation. Finally, sociotechnical interventions were evaluated using the simulation to help determine the best policy for prevention and treatment of HAIs. The best policies utilize a combination of prevention and medical treatment.",2013,13/11/2018 10:47,14/04/2020 08:34,,3938–3939,,,,,,,WSC '13,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; Review,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NHT87Y3V,conferencePaper,2013,"Barahona, Francisco; Ettl, Markus; Petrik, Marek; Rimshnick, Peter M.",Agile Logistics Simulation and Optimization for Managing Disaster Responses,Proceedings of the 2013 Winter Simulation Conference: Simulation: Making Decisions in a Complex World,,,,http://dl.acm.org/citation.cfm?id=2675807.2675811,,2013,13/11/2018 10:47,14/04/2020 08:34,,3340–3351,,,,,,,WSC '13,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4PPSMDDD,conferencePaper,2013,"Mocarzel, Bruno; Shelton, David; Uyan, Berkcan; Pérez, Eduardo; Jimenez, Jesus A.; DePagter, Lenore",Modeling and Simulation of Patient Admission Services in a Multi-specialty Outpatient Clinic,Proceedings of the 2013 Winter Simulation Conference: Simulation: Making Decisions in a Complex World,,,,http://dl.acm.org/citation.cfm?id=2676255.2676270,"Tactical planning of resources in healthcare clinics concerns elective patient admission planning and the intermediate term allocation of resource capacities. Its main objectives are to achieve equitable access for patients, to serve the strategically agreed number of patients, and to use resources efficiently. In this paper, we describe a simulation model for an outpatient healthcare clinic facing multiple issues related to patient admission and resource workflow. The main problems identified at the clinic are: 1) phones are not answered promptly and 2) patients experience long wait time to check in and check out. The simulation model focuses on the front desk operations. We investigate different resource allocation policies and report on computational results based on a real clinic, historical data, and both patient and management performance measures.",2013,13/11/2018 10:47,14/04/2020 08:34,,2309–2319,,,,,,,WSC '13,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HFMHRV3Q,conferencePaper,2013,"Melzner, Jürgen; Hollermann, Sebastian; Kirchner, Silvia; Bargstädt, Hans-Joachim",Model-based Construction Work Analysis Considering Process-related Hazards,Proceedings of the 2013 Winter Simulation Conference: Simulation: Making Decisions in a Complex World,,,,http://dl.acm.org/citation.cfm?id=2676255.2676378,,2013,13/11/2018 10:47,14/04/2020 08:34,,3203–3214,,,,,,,WSC '13,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2AZ6B8ZB,conferencePaper,2013,"Djanatliev, Anatoli; German, Reinhard","Prospective Healthcare Decision-making by Combined System Dynamics, Discrete-event and Agent-based Simulation",Proceedings of the 2013 Winter Simulation Conference: Simulation: Making Decisions in a Complex World,978-1-4799-2077-8,,,http://dl.acm.org/citation.cfm?id=2675983.2676016,Prospective Health Technology Assessment allows early decision making for innovative health care technologies. The main idea is to combine available domain knowledge with advanced simulation techniques in order to predict the effects of medical products and to find bottlenecks and weaknesses within the health system. In our recent publications a hybrid simulation approach with System Dynamics and Agent-Based Modeling has been presented. Hospital workflows have been modeled by state charts within agent behavioral models and have to be instantiated each time an agent is entering a hospital. This paper presents a mechanism to generate agents dynamically from SD models and extends the previously presented hybrid approach by process-oriented Discrete Event Simulation for hospital modeling. It connects processes to health care institutions and not to persons traversing them. Two extended example case studies show potentials for medical decision making using the three simulation paradigms in a common environment.,2013,13/11/2018 10:47,14/04/2020 08:34,,270–281,,,,,,,WSC '13,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,1; 320; agent based; Discrete event; System dynamics,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TUNJV3S3,conferencePaper,2013,"Kang, Hyojung; Nembhard, Harriet Black; Curry, William; Ghahramani, Nasrollah; Hwang, Wenke",A Systems Dynamics Approach to Support Prospective Planning of Interventions to Improve Chronic Kidney Disease Care,Proceedings of the 2013 Winter Simulation Conference: Simulation: Making Decisions in a Complex World,,,,http://dl.acm.org/citation.cfm?id=2675807.2675915,"Chronic kidney disease (CKD) is a growing health problem in the United States. Patients with CKD have had critical care gaps that have perhaps led to a more rapid progression of CKD toward end stage renal disease. To improve CKD outcomes, an interdisciplinary project has been initiated. This article describes how system dynamics supported the planning of the project. We developed a causal loop diagram through discussions with a panel advisory group and health providers. The model is particularly effective because it can demonstrate the interrelationships among patients, providers, and policies, and predict the effects of the interventions. This preliminary work may overcome the common linear approaches to care and helped design sustainable interventions through an understanding of system complexities. Future work on the project will develop a stock-flow diagram with empirical data to support the effective implementation of proposed interventions.",2013,13/11/2018 10:47,14/04/2020 08:34,,3946–3947,,,,,,,WSC '13,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,1; 320; System dynamics,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UYA8GN9K,conferencePaper,2013,"Taheri, Javad; Gellad, Ziad; Burchfield, Dariele; Cooper, Kevin",Simulation As a Guide for Systems Redesign in Gastrointestinal Endoscopy: Appointment Template Redesign,Proceedings of the 2013 Winter Simulation Conference: Simulation: Making Decisions in a Complex World,,,,http://dl.acm.org/citation.cfm?id=2676255.2676258,,2013,13/11/2018 10:47,14/04/2020 08:35,,2204–2214,,,,,,,WSC '13,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, X49LMNQN,conferencePaper,2013,"Caudill, Lester; Lawson, Barry",A Hybrid Agent-based and Differential Equations Model for Simulating Antibiotic Resistance in a Hospital Ward,Proceedings of the 2013 Winter Simulation Conference: Simulation: Making Decisions in a Complex World,,,,http://dl.acm.org/citation.cfm?id=2676128.2676162,"Serious infections due to antibiotic-resistant bacteria are pervasive, and of particular concern within hospital units due to frequent interaction among health-care workers and patients. Such nosocomial infections are difficult to eliminate because of inconsistent disinfection procedures and frequent interactions among infected persons, and because ill-chosen antibiotic treatment strategies can lead to a growth of resistant bacterial strains. Clinical studies to address these concerns have several issues, but chief among them are the effects on the patients involved. Realistic simulation models offer an attractive alternative. This paper presents a hybrid simulation model of antibiotic resistant infections in a hospital ward, combining agent-based simulation to model the inter-host interactions of patients and health-care workers with a detailed differential equations and probabilistic model of intra-host bacterial and antibiotic dynamics. Initial results to benchmark the model demonstrate realistic behavior and suggest promising extensions to achieve a highly-complex yet accurate mechanism for testing antibiotic strategies.",2013,13/11/2018 10:47,14/04/2020 08:34,,1419–1430,,,,,,,WSC '13,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,1; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 729JRNI9,conferencePaper,2013,"Macal, Charles M.; North, Michael J.",Agent-based Modeling and Simulation: Introductory Tutorial,Proceedings of the 2013 Winter Simulation Conference: Simulation: Making Decisions in a Complex World,978-1-4799-2077-8,,,http://dl.acm.org/citation.cfm?id=2675983.2676031,,2013,13/11/2018 10:47,14/04/2020 08:34,,362–376,,,,,,,WSC '13,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,1; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DKISXRVC,conferencePaper,2013,"Gavirneni, Srinagesh; Kulkarni, Vidyadhar; Manikas, Andrew; Karageorge, Alexis","Concierge Medicine: Adoption, Design, and Management",Proceedings of the 2013 Winter Simulation Conference: Simulation: Making Decisions in a Complex World,,,,http://dl.acm.org/citation.cfm?id=2676255.2676274,,2013,13/11/2018 10:47,14/04/2020 08:34,,2340–2349,,,,,,,WSC '13,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5RJLDJ94,conferencePaper,2013,"Barrett, Christopher; Bisset, Keith; Chandan, Shridhar; Chen, Jiangzhuo; Chungbaek, Youngyun; Eubank, Stephen; Evrenosoğlu, Yaman; Lewis, Bryan; Lum, Kristian; Marathe, Achla; Marathe, Madhav; Mortveit, Henning; Parikh, Nidhi; Phadke, Arun; Reed, Jeffrey; Rivers, Caitlin; Saha, Sudip; Stretz, Paula; Swarup, Samarth; Thorp, James; Vullikanti, Anil; Xie, Dawen",Planning and Response in the Aftermath of a Large Crisis: An Agent-based Informatics Framework,Proceedings of the 2013 Winter Simulation Conference: Simulation: Making Decisions in a Complex World,,,,http://dl.acm.org/citation.cfm?id=2676128.2676173,,2013,13/11/2018 10:47,14/04/2020 08:34,,1515–1526,,,,,,,WSC '13,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LB9TUXVF,conferencePaper,2013,"Metcalf, Sara; Wang, Hua; Kum, Susan; Jin, Zhu; Wang, Peng; Widener, Michael; Kunzel, Carol; Marshall, Stephen; Northridge, Mary",Modeling Social Factors of Oral Health Equity for Older Adults,Proceedings of the 2013 Winter Simulation Conference: Simulation: Making Decisions in a Complex World,,,,http://dl.acm.org/citation.cfm?id=2675807.2675943,,2013,13/11/2018 10:47,14/04/2020 08:34,,3994–3995,,,,,,,WSC '13,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HDW37LP4,conferencePaper,2007,"Bhasin, Shivam; Danger, Jean-Luc; Graba, Tarik; Mathieu, Yves; Fujimoto, Daisuke; Nagata, Makoto",Physical Security Evaluation at an Early Design-Phase: A Side-Channel Aware Simulation Methodology,Proceedings of International Workshop on Engineering Simulations for Cyber-Physical Systems,978-1-4503-2614-8,,10.1145/2589650.2559628,http://doi.acm.org/10.1145/2589650.2559628,,2007,13/11/2018 10:47,14/04/2020 08:34,,13:13–13:20,,,,,,,ES4CPS '14,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100; Design-Time security Evaluation; Side-Channel Analysis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UW978ZPF,conferencePaper,2013,"Allemann, Dominik; Raubal, Martin",Towards Health-optimal Routing in Urban Areas,Proceedings of the Second ACM SIGSPATIAL International Workshop on the Use of GIS in Public Health,978-1-4503-2529-5,,10.1145/2535708.2535713,http://doi.acm.org/10.1145/2535708.2535713,,2013,13/11/2018 10:47,14/04/2020 08:34,,56–59,,,,,,,HealthGIS '13,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100; air pollution; health atlas; health-optimal routing; mobile service; multimodality; participatory sensing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Z2NFF6GV,conferencePaper,2013,"Ghorbani, Mahboobeh; Bogdan, Paul",A Cyber-physical System Approach to Artificial Pancreas Design,Proceedings of the Ninth IEEE/ACM/IFIP International Conference on Hardware/Software Codesign and System Synthesis,978-1-4799-1417-3,,,http://dl.acm.org/citation.cfm?id=2555692.2555709,,2013,13/11/2018 10:47,14/04/2020 08:34,,17:1–17:10,,,,,,,CODES+ISSS '13,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100; artificial pancreas; cyber-physical systems; FPGA; fractal behavior; fractional calculus; non-stationary behavior; optimal and model predictive control; optimization; real time systems,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5RR77KAC,conferencePaper,2013,"Saravanan, M.; Karthikeyan, P.; Arathi, A.; Kiruthika, M.; Suganya, S.",Mobile Agent-based Approach for Modeling the Epidemics of Communicable Diseases,Proceedings of the 2013 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining,978-1-4503-2240-9,,10.1145/2492517.2492612,http://doi.acm.org/10.1145/2492517.2492612,"The increase in the use of mobile phones generates the formation of mobile social networks which can make use of various purposes including education, public health and controlling epidemics. Social networks consist of the basic building blocks called as the communities within which the social interactions are intensive, but between which they are very weak. Everyone could observe that the spread of infectious disease inside communities often has the ability to cross countries borders and spread rapidly. With the widespread of diseases causing major public health problem, we argue that human mobility patterns not only influence the spreading, but are also useful for preventing and creating awareness of the diseases. In this paper, we present new opportunities offered by the field of mobile social networks for understanding the spread of infectious diseases. For this purpose we propose two models namely MABM (Mobile Agent Based Model) and SDC (Spread Discovery Control) model to understand the spread of communicable diseases between different regions. The proposed SDC model is used to comprehend the spread of diseases by extracting the community structures and the analysis of mobility pattern of each agent (user) within the mobile network. Moreover, the understanding of spread details helps us to propose the control strategy to avoid the spread of the epidemic disease on the specific region. To realize our proposed models in a better way, we have modeled one such communicable disease usually spreading every year in West African region.",2013,13/11/2018 10:47,14/04/2020 08:35,,16–20,,,,,,,ASONAM '13,,,,ACM,"New York, NY, USA",,,,,,,,,,,,1; 100; Agent Based; community mining; influential user; MABM; SDC; social networks,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5U7KLVKM,conferencePaper,2013,"Chung, Kon Shing Kenneth; Young, Jane; White, Kate",Towards a Networks-enabled Complexity Profile for Examining Responsibility for Decision-making by Healthcare Professionals,Proceedings of the 2013 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining,978-1-4503-2240-9,,10.1145/2492517.2500324,http://doi.acm.org/10.1145/2492517.2500324,"Complexity is generally accepted to be the interrelatedness of components within a system. Treating the general practitioner (GP)-patient encounter as a complex system, we argue that complexity (resulting from the degree of interactions between GP, colleagues, patient) determines the performance of GPs, measured by attitudes to responsibility for their decisions about patient treatment. In this paper, we propose the use of social network measures of `density' and `inclusiveness' for computing the `interrelatedness' of components within a complex system. We also suggest the use of `number of components' (NoC) and `degree of interrelatedness' (DoI) to plot the complexity profiles for each GP. Results from a sample of 107 GPs show that GPs with simple profiles (i.e. low NoC & low DoI), compared to those in non-simple profiles, indicate a higher responsibility for the decisions they make in medical care. In conclusion, we argue that social networks-based complexity profiles are useful for understanding responsibility-taking in primary care. We highlight a number of interesting insights and practical implications for healthcare professionals.",2013,13/11/2018 10:47,14/04/2020 08:34,,998–1003,,,,,,,ASONAM '13,,,,ACM,"New York, NY, USA",,,,,,,,,,,,1; 110; complex social network; complexity; density; general practitioners; inclusiveness; interrelatedness; performance; quality of care; reponsibility-taking,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DSFUI5YL,conferencePaper,2013,"Huang, Liang-Cheng; Liu, Wei-Chung; Chou, Seng-Cho T.",Howcare: A Personal Health Cloud Archive and Care-partners' Community,Proceedings of the 2013 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining,978-1-4503-2240-9,,10.1145/2492517.2500237,http://doi.acm.org/10.1145/2492517.2500237,,2013,13/11/2018 10:47,14/04/2020 08:34,,1237–1241,,,,,,,ASONAM '13,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 110; caregiver; health cloud; online health community; personal health information; social support,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MPWAHXT8,conferencePaper,2013,"Biyani, Prakhar; Caragea, Cornelia; Mitra, Prasenjit; Zhou, Chong; Yen, John; Greer, Greta E.; Portier, Kenneth",Co-training over Domain-independent and Domain-dependent Features for Sentiment Analysis of an Online Cancer Support Community,Proceedings of the 2013 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining,978-1-4503-2240-9,,10.1145/2492517.2492606,http://doi.acm.org/10.1145/2492517.2492606,,2013,13/11/2018 10:47,14/04/2020 08:34,,413–417,,,,,,,ASONAM '13,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100; co-training; direct emotional support; indirect emotional support; online health community; sentiment analysis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NAK4Z6JA,conferencePaper,2013,"Nikolaev, Alexander; McIntosh, Scott",On the Value of Weak Ties for Modeling Interventions in Online Health Communities,Proceedings of the 2013 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining,978-1-4503-2240-9,,10.1145/2492517.2500306,http://doi.acm.org/10.1145/2492517.2500306,"Online pro-health social networks have grown in the past decade. This position paper argues for the need of prescriptive research that would enable models of online interventions capable of assessing the effects imposed on social networks from the outside, e.g., by a strategic decision-maker (supervisor) possessing the full knowledge of the network dynamics. The paper explains the importance of explicit modeling of weak, acquaintance-type ties for this purpose.",2013,13/11/2018 10:47,14/04/2020 08:35,,1481–1482,,,,,,,ASONAM '13,,,,ACM,"New York, NY, USA",,,,,,,,,,,,1; 110; intervention modeling; online health behavior; social network analysis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, J7T8MVCW,conferencePaper,2013,"Parker, Jon; Wei, Yifang; Yates, Andrew; Frieder, Ophir; Goharian, Nazli",A Framework for Detecting Public Health Trends with Twitter,Proceedings of the 2013 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining,978-1-4503-2240-9,,10.1145/2492517.2492544,http://doi.acm.org/10.1145/2492517.2492544,"Traditional public health surveillance requires regular clinical reports and considerable effort by health professionals to analyze data. Therefore, a low cost alternative is of great practical use. As a platform used by over 500 million users worldwide to publish their ideas about many topics, including health conditions, Twitter provides researchers the freshest source of public health conditions on a global scale. We propose a framework for tracking public health condition trends via Twitter. The basic idea is to use frequent term sets from highly purified health-related tweets as queries into a Wikipedia article index - treating the retrieval of medically-related articles as an indicator of a health-related condition. By observing fluctuations in frequent term sets and in turn medically-related articles over a series of time slices of tweets, we detect shifts in public health conditions and concerns over time. Compared to existing approaches, our framework provides a general a priori identification of emerging public health conditions rather than a specific illness (e.g., influenza) as is commonly done.",2013,13/11/2018 10:47,14/04/2020 08:35,,556–563,,,,,,,ASONAM '13,,,,ACM,"New York, NY, USA",,,,,,,,,,,,1; 110; health surveillance; item-set mining; Twitter; Wikipedia,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PJ2WMLMY,conferencePaper,2013,"Besaleva, Liliya I.; Weaver, Alfred C.",Mobile Electronic Triaging for Emergency Response Improvement Through Crowdsourced and Sensor-detected Information,Proceedings of the 2013 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining,978-1-4503-2240-9,,10.1145/2492517.2500327,http://doi.acm.org/10.1145/2492517.2500327,,2013,13/11/2018 10:47,14/04/2020 08:34,,1092–1093,,,,,,,ASONAM '13,,,,ACM,"New York, NY, USA",,,,,,,,,,,,human factors; clusterization; crowdsourcing; feedback; location; mobile devices; sensors; triage tagging; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CZZQVR72,conferencePaper,2013,"Aggour, Kareem S.; Hoogs, Bethany; Leber, Christina; Correia, Carry; Senturk-Doganaksoy, Deniz",Mining Company Networks for Marketing Insights and Sales Leads,Proceedings of the 2013 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining,978-1-4503-2240-9,,10.1145/2492517.2500227,http://doi.acm.org/10.1145/2492517.2500227,"Traditional sales support systems offer an insular view of companies, providing information on a target company and that company alone. This view presents each company as if it operates independently from its surroundings. However, a company can be more effectively evaluated when it is viewed not in isolation, but in the context of its network of customers and suppliers. Here we describe a system developed for GE Capital that enables sales representatives to analyze a target company's network of business relationships to gain deeper insights into its status. Mining company networks enables novel approaches to generating sales leads by taking advantage of information about the health and status of the suppliers and customers to which the company is linked. The system allows sales reps to visualize company networks and provides a variety of filters and views to mine the network information. This gives the sales reps deeper insights into their prospect pool, enabling them to be more knowledgeable and generate more actionable sales leads.",2013,13/11/2018 10:47,14/04/2020 08:34,,805–812,,,,,,,ASONAM '13,,,,ACM,"New York, NY, USA",,,,,,,,,,,,supplier; commercial financing; company network; customer; network mining; sales lead generation; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IBYRQSWI,conferencePaper,2013,"Wei, Lei; Nahavandi, Saeid; Weisinger, Harrison",Optometry Training Simulation with Augmented Reality and Haptics,Proceedings of the 2013 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining,978-1-4503-2240-9,,10.1145/2492517.2500326,http://doi.acm.org/10.1145/2492517.2500326,,2013,13/11/2018 10:47,14/04/2020 08:35,,976–977,,,,,,,ASONAM '13,,,,ACM,"New York, NY, USA",,,,,,,,,,,,augmented reality; foreign body removal; haptics; optometry simulation; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, M6P5HV3X,conferencePaper,2013,"Levula, Andrew V.; Chung, Kon Shing Kenneth; Young, Jane; White, Kate",Envisioning Complexity in Healthcare Systems Through Social Networks,Proceedings of the 2013 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining,978-1-4503-2240-9,,10.1145/2492517.2500313,http://doi.acm.org/10.1145/2492517.2500313,"In this study, we develop an Aggregate Complexity Framework (ACF) for envisioning complexity for care coordination. This framework provides an empirical foundation that can be adopted for better understanding and characterizing aggregate complexity in healthcare systems through the use of social network measures. Complexity is defined as the interrelatedness of components within a system. For instance, healthcare systems are characterized as complex adaptive system as they consist of multidisciplinary teams that have strong interdependences as healthcare professionals are required to coordinate effectively and share resources for positive patient outcomes. This aggregate complexity framework can be used to capture the number of components (e.g. professionals, technology, other artifacts etc.) and the degree of interrelatedness between the components (the level of influence the components have on one another) within a system. The contribution that this study makes to the field is 1) better understanding of aggregate complexity and coordination 2) a theoretical model which can be used to further understand the challenges of care coordination in cancer settings and 3) practical implications for aggregate complexity framework for envisioning organizations and healthcare systems.",2013,13/11/2018 10:47,14/04/2020 08:34,,931–936,,,,,,,ASONAM '13,,,,ACM,"New York, NY, USA",,,,,,,,,,,,social network; aggregate complexity; complex adaptive systems; coordination; density; 1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JTURTGMD,conferencePaper,2013,"Salamati, Farzaneh; Pasek, Zbigniew J.",Modeling for Personal Well-being: Time for Paradigm Change,Proceedings of the 2013 Grand Challenges on Modeling and Simulation Conference,978-1-62748-275-2,,,http://dl.acm.org/citation.cfm?id=2557668.2557679,"The growing demand for health services tied to exploding costs are a growing concern for all national health care systems, which are reaching their limits of volume and case complexities. In the long run reliance on institutional health care delivery systems is not sustainable and may require shifting responsibilities of health management to individuals. Such a shift would require major paradigm change by focusing on individual's well-being and providing tools for its management. For example, by 2015, it is expected that one of every three people worldwide will be overweight and one in ten -- obese. Considering that while preventable, obesity is responsible for over 60% of all leading death causes in developed societies, it is critical to understand the mechanisms that may lead to its control. The obesity model presented in the paper was developed using system dynamics and is based on three-factor models combined into an energy balance equation. The results were tested with weight loss clinic data. Tools for quantified self-tracking may provide an automated source for data collection needed to refine the model and estimated individual characteristics needs as model parameters.",2013,13/11/2018 10:47,14/04/2020 08:34,,11:1–11:5,,,,,,,GCMS '13,,,,Society for Modeling & Simulation International,"Vista, CA",,,,,,,,,,,,obesity; system dynamics; individualized health care; self-tracking; 1; X,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, I2BFAQKH,conferencePaper,2013,"Delaney, Liam; Kleczkowski, Adam; Maharaj, Savi; Rasmussen, Susan; Williams, Lynn",Reflections on a Virtual Experiment Addressing Human Behavior During Epidemics,Proceedings of the 2013 Summer Computer Simulation Conference,978-1-62748-276-9,,,http://dl.acm.org/citation.cfm?id=2557696.2557732,,2013,13/11/2018 10:47,14/04/2020 08:34,,33:1–33:8,,,,,,,SCSC '13,,,,Society for Modeling & Simulation International,"Vista, CA",,,,,,,,,,,,participatory simulation; behavioral economics; epidemics; health psychology; virtual experiments; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TZAIAP5Z,conferencePaper,2013,"Djanatliev, Anatoli; German, Reinhard",Large Scale Healthcare Modeling by Hybrid Simulation Techniques Using AnyLogic,Proceedings of the 6th International ICST Conference on Simulation Tools and Techniques,978-1-4503-2464-9,,,http://dl.acm.org/citation.cfm?id=2512734.2512769,"In contrast to already established tools for health technology assessments, Prospective Health Technology Assessment (ProHTA) uses hybrid simulation techniques to make early predictions about the effects of new healthcare innovations. In such studies, it is necessary to consider problems at high abstraction levels, as well as at detailed microscopic levels. According to the diversity of expected output metrics and the lack of medical evidence, the situation can be compared to other large scale and complex simulation problems. In such cases well-known modeling methods are often not sufficient to use. Therefore, advanced modeling and simulation techniques have to be developed and properly applied. This paper describes a methodical and practical approach of hybrid model creation using the simulation tool AnyLogic. We focus on general modeling aspects and on advanced techniques using a Level-Based Architecture that help to develop large scale hybrid simulation models. An implementation of a stroke therapy use-case and its simulation results will be discussed. Finally, some practical ideas for validation will be outlined, as we experienced during the stroke use-case development.",2013,13/11/2018 10:47,14/04/2020 08:34,,248–257,,,,,,,SimuTools '13,,,,"ICST (Institute for Computer Sciences, Social-Informatics and Telecommunications Engineering)","ICST, Brussels, Belgium, Belgium",,,,,,,,,,,,system dynamics; healthcare; agent-based simulation; hybrid simulation; large scale modeling; modeling and simulation; multi-paradigm modeling; technology assessment; 1; 100; 120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GAEQI3CU,journalArticle,2013,"Suchard, Marc A.; Simpson, Shawn E.; Zorych, Ivan; Ryan, Patrick; Madigan, David",Massive Parallelization of Serial Inference Algorithms for a Complex Generalized Linear Model,ACM Trans. Model. Comput. Simul.,,1049-3301,10.1145/2414416.2414791,http://doi.acm.org/10.1145/2414416.2414791,,2013-01,13/11/2018 10:47,14/04/2020 08:35,,10:1–10:17,,1,23,,,,,,,,,,,,,,,,,,,,,big data; Optimization; parallel processing; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6452Q2IX,conferencePaper,2012,"Götz, Olav; Bullmann, Claudia; Zach, Maria; Tost, Frank; Fleßa, Steffen",Using Discrete-event Simulation to Analyze the Process of Cataract Inter-vention at a University Hospital Outpatient Department,Proceedings of the Winter Simulation Conference,,,,http://dl.acm.org/citation.cfm?id=2429759.2430185,,2012,13/11/2018 10:47,14/04/2020 08:34,,316:1–316:1,,,,,,,WSC '12,,,,Winter Simulation Conference,"Berlin, Germany",,,,,,,,,,,,00; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, U65Y9FLV,conferencePaper,2012,"Macal, Charles M.; North, Michael J.; Collier, Nicholson; Dukic, Vanja M.; Lauderdale, Diane S.; David, Michael Z.; Daum, Robert S.; Shumm, Philip; Daum, Robert S.; Evans, James A.; Wilder, Jocelyn R.; Wegener, Duane T.",Modeling the Spread of Community-associated MRSA,Proceedings of the Winter Simulation Conference,,,,http://dl.acm.org/citation.cfm?id=2429759.2429855,"Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) are strains of the bacterium S. aureus that are responsible for skin and soft tissue, blood, bone, and other infections that can be life threatening. CA-MRSA strains are resistant to standard antibiotics related to penicillins and have a high prevalence in the general community, as well as in healthcare facilities. CA-MRSA presents novel challenges for computational epidemiological modeling compared to other commonly modeled diseases. CA-MRSA challenges include modeling activities and contact processes of individuals in which direct skin contact can be an important infection pathway, estimating disease transmission parameters based on limited data, and representing behavioral responses of individuals to the disease and healthcare interventions. We are developing a fine-grained agent-based model of CA-MRSA for the Chicago metropolitan area. This paper describes how we are modeling CA-MRSA disease processes based on variants of standard epidemiological models and individual agent-based approaches.",2012,13/11/2018 10:47,14/04/2020 08:34,,73:1–73:12,,,,,,,WSC '12,,,,Winter Simulation Conference,"Berlin, Germany",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KFLCD7YU,conferencePaper,2012,"Zhang, Tianyou; Lees, Michael; Kwoh, Chee Keong; Fu, Xuju; Lee, Gary Kee Khoon; Goh, Rick Siow Mong","A Contact-network-based Simulation Model for Evaluating Interventions Under ""What-if"" Scenarios in Epidemic",Proceedings of the Winter Simulation Conference,,,,http://dl.acm.org/citation.cfm?id=2429759.2430298,"Infectious disease pandemics/epidemics have been serious concerns worldwide. Simulations for public health interventions are practically helpful in assisting policy makers to make wise decisions to control and mitigate the spread of infectious diseases. In this paper, we present our contact network based simulation model, which is designed to accommodate various ""what-if"" scenarios under single and combined interventions. With the incorporation of parallel computing and optimization techniques, our model is able to reflect the dynamics of disease spread in a realistic social contact network based on Singapore city, simulating combined intervention strategies as well as control effect at different levels of a social component. The framework of our model and experimental results show that it is a useful tool for epidemiological study and public health policy planning.",2012,13/11/2018 10:47,14/04/2020 08:35,,416:1–416:12,,,,,,,WSC '12,,,,Winter Simulation Conference,"Berlin, Germany",,,,,,,,,,,,1; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CDZ3HR7T,conferencePaper,2012,"Noble, Jason; Silverman, Eric; Bijak, Jakub; Rossiter, Stuart; Evandrou, Maria; Bullock, Seth; Vlachantoni, Athina; Falkingham, Jane",Linked Lives: The Utility of an Agent-based Approach to Modeling Partnership and Household Formation in the Context of Social Care,Proceedings of the Winter Simulation Conference,,,,http://dl.acm.org/citation.cfm?id=2429759.2429882,"The UK's population is aging, which presents a challenge as older people are the primary users of health and social care services. We present an agent-based model of the basic demographic processes that impinge on the supply of, and demand for, social care: namely mortality, fertility, health-status transitions, internal migration, and the formation and dissolution of partnerships and households. Agent-based modeling is used to capture the idea of ""linked lives"" and thus to represent hypotheses that are impossible to express in alternative formalisms. Simulation runs suggest that the per-taxpayer cost of state-funded social care could double over the next forty years. A key benefit of the approach is that we can treat the average cost of state-funded care as an outcome variable, and examine the projected effect of different sets of assumptions about the relevant social processes.",2012,13/11/2018 10:47,14/04/2020 08:35,,93:1–93:12,,,,,,,WSC '12,,,,Winter Simulation Conference,"Berlin, Germany",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8ZZ9QP5K,conferencePaper,2012,"Zulkepli, Jafri; Eldabi, Tillal; Mustafee, Navonil",Hybrid Simulation for Modelling Large Systems: An Example of Integrated Care Model,Proceedings of the Winter Simulation Conference,,,,http://dl.acm.org/citation.cfm?id=2429759.2429848,"Developing models for large systems is not a trivial task. Using only Discrete Event Simulation (DES) as a modelling technique may mean that the complexity of the underlying model will increase exponentially with the size of the model. An alternative to this is the use of System Dynamics (SD) for modeling large systems using the positive and negative feedback loops. However, for modelling a human-centric system like healthcare, DES is important as it provides individuality analysis; similarly, SD is important as it facilitates the whole systems approach. The combined application of OR/Simulation methods enable the symbiotic realization of the strengths of individual techniques, while reducing their limitations; in this paper it is suggested that a combined SD-DES approach (also referred to as hybrid technique) can be effectively used for modelling large systems. The example being used in this context is the modelling of an Integrated Care (IC) system in healthcare.",2012,13/11/2018 10:47,14/04/2020 08:34,,68:1–68:12,,,,,,,WSC '12,,,,Winter Simulation Conference,"Berlin, Germany",,,,,,,,,,,,System Dynamics; 1; Hybrid simulation; *****; Discrete event; 210,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 486REACT,conferencePaper,2012,"Mes, Martijn; Bruens, Manon",A Generalized Simulation Model of an Integrated Emergency Post,Proceedings of the Winter Simulation Conference,,,,http://dl.acm.org/citation.cfm?id=2429759.2429862,"This paper discusses the development of a discrete-event simulation model for an integrated emergency post. This post is a collaboration between a general practitioners post and an emergency department within a hospital. We present a generalized and flexible simulation model, which can easily be adapted to several emergency departments as well as to other departments within the hospital, as we demonstrate with our application to the integrated emergency post. Here, generalization relates to the way we model patient flow, patient prioritization, resource allocation, and process handling. After presenting the modeling approach, we shortly describe the implemented and validated model of the integrated emergency post, and describe how it is currently being used by health care managers to analyze the effects of organizational interventions.",2012,13/11/2018 10:47,14/04/2020 08:34,,78:1–78:11,,,,,,,WSC '12,,,,Winter Simulation Conference,"Berlin, Germany",,,,,,,,,,,,1; Discrete event; 210,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FMXSABA8,conferencePaper,2012,"Haddad, Hedi; Moulin, Bernard; Thériault, Marius; Navarro-Velazquez, Daniel",Integrated Epidemiologic Simulation for Person to Person Contagion Through Urban Mobility Within GIS,Proceedings of the First ACM SIGSPATIAL International Workshop on Use of GIS in Public Health,978-1-4503-1703-0,,10.1145/2452516.2452529,http://doi.acm.org/10.1145/2452516.2452529,,2012,13/11/2018 10:47,14/04/2020 08:34,,63–71,,,,,,,HealthGIS '12,,,,ACM,"New York, NY, USA",,,,,,,,,,,,spatial-temporal simulation; communicable infectious diseases; GIS; public health decision support; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IXUJ87DL,conferencePaper,2012,"Lin, Mu; Lane, Nicholas D.; Mohammod, Mashfiqui; Yang, Xiaochao; Lu, Hong; Cardone, Giuseppe; Ali, Shahid; Doryab, Afsaneh; Berke, Ethan; Campbell, Andrew T.; Choudhury, Tanzeem",BeWell+: Multi-dimensional Wellbeing Monitoring with Community-guided User Feedback and Energy Optimization,Proceedings of the Conference on Wireless Health,978-1-4503-1760-3,,10.1145/2448096.2448106,http://doi.acm.org/10.1145/2448096.2448106,,2012,13/11/2018 10:47,14/04/2020 08:34,,10:1–10:8,,,,,,,WH '12,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YT8CUKG5,conferencePaper,2012,"Xu, Rui-tian; Zhang, Jun",Estimating Markov Switching Model Using Differential Evolution Algorithm in Prospective Infectious Disease Outbreak Detection,Proceedings of the 14th Annual Conference on Genetic and Evolutionary Computation,978-1-4503-1177-9,,10.1145/2330163.2330326,http://doi.acm.org/10.1145/2330163.2330326,,2012,13/11/2018 10:47,14/04/2020 08:35,,1183–1190,,,,,,,GECCO '12,,,,ACM,"New York, NY, USA",,,,,,,,,,,,time series analysis; differential evolution; identifiability constraint; label switching problem; markov switching model; maximum likelihood estimation; prospective infectious disease outbreak detection; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, K3E6PNLU,conferencePaper,2012,"Shafiee, Ehsan; Zechman, Emily",Integrating Evolutionary Computation and Sociotechnical Simulation for Flushing Contaminated Water Distribution Systems,Proceedings of the 14th Annual Conference Companion on Genetic and Evolutionary Computation,978-1-4503-1178-6,,10.1145/2330784.2330830,http://doi.acm.org/10.1145/2330784.2330830,,2012,13/11/2018 10:47,14/04/2020 08:35,,315–322,,,,,,,GECCO '12,,,,ACM,"New York, NY, USA",,,,,,,,,,,,optimization; agent-based modeling; evolutionary strategy; flushing; opening hydrants; technical response action; water distribution contamination event; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9XV44LBS,conferencePaper,2012,"Diaz, Rafael; Behr, Joshua; Jeng, Anna; Lu, Hua; Longo, Franceso",Analyzing the Effects of Policy Options to Mitigate the Effect of Sea Level Rise on the Public Health and Medically Fragile Population: A System Dynamics Approach,Proceedings of the 2012 Symposium on Emerging Applications of M&S in Industry and Academia Symposium,978-1-61839-787-4,,,http://dl.acm.org/citation.cfm?id=2338790.2338795,,2012,13/11/2018 10:47,14/04/2020 08:34,,5:1–5:8,,,,,,,EAIA '12,,,,Society for Computer Simulation International,"San Diego, CA, USA",,,,,,,,,"

Emerging M&S Applications in Industry and Academia Symposium (EAIA 2012), Orlando, FL, MAR 26-30, 2012

",,,public health; resource allocation; sea level rise; system dynamics; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MJIP2ASF,conferencePaper,2012,"Singh, Ranjit; Sharman, Raj; Anderson, Diana; Singh, Ashok; Singh, Gurdev",Healthcare Simulation for Excellence in In-patient Safety,Proceedings of the 2012 Symposium on Emerging Applications of M&S in Industry and Academia Symposium,978-1-61839-787-4,,,http://dl.acm.org/citation.cfm?id=2338790.2338801,"In the US healthcare alone over 25,000 patients are sickened, injured or killed each day. The associated huge, tangible and intangible, costs are crippling burdens on all stakeholders. In the USA the national health budget is 1/6 of the GDP, of which 1/3 is estimated to be wasted. The United Nations World Health Organization is working toward making patient safety a Basic Human Right. A safe organization is a cost-effective quality organization wherein all stakeholders are trained to understand work processes and their role in them. Simulation-based program for training individuals and teams, which has a great potential to deliver high reliability care, is put forward by the authors. The simulations are structured around the Accident Trajectory that describes how incidents result from a combination of situational factors and system failures that predispose individuals to make mistakes (active errors). Details of this highly transferrable training methodology and the tools that help inculcate leadership, systems thinking, communication, situational awareness, teamwork, consensus-based problem solving and decision making, as well as adaptive responsiveness are presented. This is followed by proposed methods of assessment of resulting individual and team competencies. Also described are details of the formative assessment of the approach.",2012,13/11/2018 10:47,14/04/2020 08:35,,11:1–11:8,,,,,,,EAIA '12,,,,Society for Computer Simulation International,"San Diego, CA, USA",,,,,,,,,"

Emerging M&S Applications in Industry and Academia Symposium (EAIA 2012), Orlando, FL, MAR 26-30, 2012

",,,safety; patient; healthcare; hospital; high reliability organization; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VUU7N2RW,conferencePaper,2012,"Kikuchi, Shinji; Sachdeva, Shelly; Bhalla, Subhash",Applying Cloud Computing Model in PHR Architecture,Proceedings of the 2012 Joint International Conference on Human-Centered Computer Environments,978-1-4503-1191-5,,10.1145/2160749.2160798,http://doi.acm.org/10.1145/2160749.2160798,,2012,13/11/2018 10:47,14/04/2020 08:34,,236–237,,,,,,,HCCE '12,,,,ACM,"New York, NY, USA",,,,,,,,,,,,personal health record; architecture; cloud computing; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CIIYSYTZ,conferencePaper,2012,"Tan, Wang-Chiew; Haas, Peter J.; Mak, Ronald L.; Kieliszewski, Cheryl A.; Selinger, Patricia G.; Maglio, Paul P.; Glissman, Susanne; Cefkin, Melissa; Li, Yinan",Splash: A Platform for Analysis and Simulation of Health,Proceedings of the 2Nd ACM SIGHIT International Health Informatics Symposium,978-1-4503-0781-9,,10.1145/2110363.2110424,http://doi.acm.org/10.1145/2110363.2110424,,2012,13/11/2018 10:47,14/04/2020 08:35,,543–552,,,,,,,IHI '12,,,,ACM,"New York, NY, USA",,,,,,,,,,,,workflow; data analysis; schema mappings; simulation model composition; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, L9HVGVNH,conferencePaper,2012,"Barrett, Chris; Beckman, Richard; Bisset, Keith; Chen, Jiangzhuo; DuBois, Thomas; Eubank, Stephen; Kumar, V.S. Anil; Lewis, Bryan; Marathe, Madhav V.; Srinivasan, Aravind; Stretz, Paula E.",Optimizing Epidemic Protection for Socially Essential Workers,Proceedings of the 2Nd ACM SIGHIT International Health Informatics Symposium,978-1-4503-0781-9,,10.1145/2110363.2110371,http://doi.acm.org/10.1145/2110363.2110371,,2012,13/11/2018 10:47,14/04/2020 08:34,,31–40,,,,,,,IHI '12,,,,ACM,"New York, NY, USA",,,,,,,,,,,,optimization; epidemiology; public health informatics; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6W3KKT5R,conferencePaper,2011,"Barnes, Sean; Wasil, Edward; Golden, Bruce; Furuno, Jon; Harris, Anthony",An Application of Factorial Design to Compare the Relative Effectiveness of Hospital Infection Control Measures,Proceedings of the Winter Simulation Conference,,,,http://dl.acm.org/citation.cfm?id=2431518.2431671,"Optimal methods to control patient-to-patient transmission of methicillin-resistant Staphylococcus aureus (MRSA) in an intensive care unit (ICU) setting are still unknown. We iteratively applied a full 2k factorial design on the output of a stochastic, agent-based simulation to compare the effects of the hand hygiene compliance of healthcare workers and the nurse-to-patient ratio on the transmission of MRSA in a 20-bed ICU. The results suggest that increasing the nurse-to-patient ratio is more effective at levels below approximately 60% compliance of nurses. However, improving the hand washing compliance of nurses becomes the better strategy at higher baseline compliance levels. In addition, interaction effects between the two infection control measures limit the marginal benefit of improving both factors to high levels.",2011,13/11/2018 10:47,14/04/2020 08:34,,1283–1294,,,,,,,WSC '11,,,,Winter Simulation Conference,"Phoenix, Arizona",,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EQS8LDT7,conferencePaper,2011,"Shylo, Oleg V.; Luangkesorn, Louis; Prokopyev, Oleg A.; Rajgopal, Jayant; Schaefer, Andrew",Managing Patient Backlog in a Surgical Suite That Uses a Block-booking Scheduling System,Proceedings of the Winter Simulation Conference,,,,http://dl.acm.org/citation.cfm?id=2431518.2431676,,2011,13/11/2018 10:47,14/04/2020 08:35,,1319–1329,,,,,,,WSC '11,,,,Winter Simulation Conference,"Phoenix, Arizona",,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, M374QEBJ,conferencePaper,2011,"Mousavi, Alireza; Komashie, Alexander; Tavakoli, Siamak",Ulation-based Real-time Performance Itoring (SIMMON): A Platform for Manufacturing and Healthcare Systems,Proceedings of the Winter Simulation Conference,,,,http://dl.acm.org/citation.cfm?id=2431518.2431589,"This paper introduces a new technology platform that improves the efficiency and effectiveness of simulation modelling projects. A recently developed platform that integrates data acquisition management platform (primary models) and post simulation performance analysis models (synthesis) is described. The use of real-time discrete event simulation modelers as a vehicle is proposed. In recent years we have suggested a number of solutions to integrate shopfloor data with higher level information systems. All these solutions lacked two key capabilities. Firstly, the solutions were not capable of interacting with data acquisition systems with-out expert interference in determining the quality and quantity of input signals. Therefore, connecting in-put signals to key performance indicators (i.e. simulation parameters) was extremely challenging and error prone. Secondly, from health workers' and plant managers' perspective, simulation results (e.g. resource utilization, waiting times, work-in-process, etc.) did not correspond to industry performance metrics. SIMMON is proposed here to address these two problems.",2011,13/11/2018 10:47,14/04/2020 08:35,,600–611,,,,,,,WSC '11,,,,Winter Simulation Conference,"Phoenix, Arizona",,,,,,,,,,,,1; ******To read; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, U82YLTMV,conferencePaper,2011,"Adam, Ng; Sy, Charlle; Li, Jie; Sheng, Tsan",A System Dynamics Model of Singapore Healthcare Affordability,Proceedings of the Winter Simulation Conference,,,,http://dl.acm.org/citation.cfm?id=2431518.2431674,"In many countries, healthcare expenditure has witnessed an accelerated pace of increase over the years. This has placed a strain on both public and private sectors to effectively mitigate the surmounting pressures of healthcare costs, affordability and accessibility. This paper looks into these issues within Singapore's healthcare system. The system dynamics simulation method has been used to elucidate complexities brought about by multiple interconnected subsystems and their complex relationships. Simulations have been carried out to understand how the different entities in the system influence healthcare affordability. For instance, this included observing how demand for hospital services affected the various critical hospital resources and their respective costs. Four different classes of policies have then been developed and subsequently tested for their effectiveness in improving healthcare affordability.",2011,13/11/2018 10:47,14/04/2020 08:34,,1306–1318,,,,,,,WSC '11,,,,Winter Simulation Conference,"Phoenix, Arizona",,,,,,,,,,,,00; Review,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RZ24XAJ4,conferencePaper,2011,"Smith, Philip; Hradisky, Michal; Thornock, Jeremy; Spinti, Jennifer; Nguyen, Diem",Large Eddy Simulation of a Turbulent Buoyant Helium Plume,"Proceedings of the 2011 Companion on High Performance Computing Networking, Storage and Analysis Companion",978-1-4503-1030-7,,10.1145/2148600.2148671,http://doi.acm.org/10.1145/2148600.2148671,,2011,13/11/2018 10:47,14/04/2020 08:35,,135–136,,,,,,,SC '11 Companion,,,,ACM,"New York, NY, USA",,,,,,,,,,,,validation; buoyant plume; combustion; CRD; LES; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PYGQ57D3,journalArticle,2011,"Massey, William A.; Pender, Jamol",Poster: Skewness Variance Approximation for Dynamic Rate MultiServer Queues with Abandonment,SIGMETRICS Perform. Eval. Rev.,,0163-5999,10.1145/2034832.2034858,http://doi.acm.org/10.1145/2034832.2034858,,2011-09,13/11/2018 10:47,14/04/2020 08:34,,74–74,,2,39,,,,,,,,,,,,,,,,,,,,,100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 86M6FZ6T,journalArticle,2011,"Günal, Murat M.; Pidd, Michael",DGHPSIM:: Generic Simulation of Hospital Performance,ACM Trans. Model. Comput. Simul.,,1049-3301,10.1145/2000494.2000496,http://doi.acm.org/10.1145/2000494.2000496,"The British National Health Service (NHS) has a performance management framework that aims to guarantee short waiting times for patients by including mandatory targets for hospitals. DGHPSim is a suite of four components that simulates the activities of an NHS general hospital to show the effect of different policies on waiting times in these hospitals. DGHPSim has a generic structure that is used to simulate a particular hospital by employing data appropriate to that hospital from available data sets. Two of the components of DGHPSim, the accident and emergency simulator and the outpatient simulator, may be used independently as stand-alone simulators of these hospital functions. The DGHPSim suite incorporates a novel way of simulating the multitasking behavior of clinicians and uses transition matrices, extracted from standard datasets, to represent the states through which patients pass and the wards in which they may be treated. As a whole, the DGHPSim suite may be used to investigate improvement options before their implementation or to investigate how a hospital has improved its performance. We show how DGHPSim is used to investigate reported performance improvements in an English general hospital",2011-09,13/11/2018 10:47,14/04/2020 08:34,,23:1–23:22,,4,21,,,,,,,,,,,,,,,,,,,,,Generic simulation; healthcare systems modeling; hospital modeling; 1; Discrete event; 210,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BD3EM99S,conferencePaper,2011,"Mimno, David; Wallach, Hanna M.; Talley, Edmund; Leenders, Miriam; McCallum, Andrew",Optimizing Semantic Coherence in Topic Models,Proceedings of the Conference on Empirical Methods in Natural Language Processing,978-1-937284-11-4,,,http://dl.acm.org/citation.cfm?id=2145432.2145462,,2011,13/11/2018 10:47,14/04/2020 08:34,,262–272,,,,,,,EMNLP '11,,,,Association for Computational Linguistics,"Stroudsburg, PA, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CBKCNCUC,conferencePaper,2011,"Shafiee, M. Ehsan; Zechman, Emily M.",Sociotechnical Simulation and Evolutionary Algorithm Optimization for Routing Siren Vehicles in a Water Distribution Contamination Event,Proceedings of the 13th Annual Conference Companion on Genetic and Evolutionary Computation,978-1-4503-0690-4,,10.1145/2001858.2002046,http://doi.acm.org/10.1145/2001858.2002046,,2011,13/11/2018 10:47,14/04/2020 08:35,,543–550,,,,,,,GECCO '11,,,,ACM,"New York, NY, USA",,,,,,,,,,,,optimization; agent-based modeling; threat management; water distribution contamination; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, S99KBSS6,conferencePaper,2011,"Gomide, Janaína; Veloso, Adriano; Meira, Wagner, Jr.; Almeida, Virgílio; Benevenuto, Fabrício; Ferraz, Fernanda; Teixeira, Mauro",Dengue Surveillance Based on a Computational Model of Spatio-temporal Locality of Twitter,Proceedings of the 3rd International Web Science Conference,978-1-4503-0855-7,,10.1145/2527031.2527049,http://doi.acm.org/10.1145/2527031.2527049,,2011,13/11/2018 10:47,14/04/2020 08:34,,3:1–3:8,,,,,,,WebSci '11,,,,ACM,"New York, NY, USA",,,,,,,,,,,,data mining; Twitter; Dengue; spatio-temporal data mining; surveillance; web; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LQSP32LJ,conferencePaper,2011,"Leidig, Jonathan; Fox, Edward A.; Hall, Kevin; Marathe, Madhav; Mortveit, Henning",SimDL: A Model Ontology Driven Digital Library for Simulation Systems,Proceedings of the 11th Annual International ACM/IEEE Joint Conference on Digital Libraries,978-1-4503-0744-4,,10.1145/1998076.1998091,http://doi.acm.org/10.1145/1998076.1998091,,2011,13/11/2018 10:47,14/04/2020 08:34,,81–84,,,,,,,JCDL '11,,,,ACM,"New York, NY, USA",,,,,,,,,,,,collections; domain ontologies; simulations; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HND6XC2X,conferencePaper,2011,"Chodos, David; Stroulia, Eleni; King, Sharla",Developing a Virtual-world Simulation,Proceedings of the 3rd Workshop on Software Engineering in Health Care,978-1-4503-0585-3,,10.1145/1987993.1988007,http://doi.acm.org/10.1145/1987993.1988007,,2011,13/11/2018 10:47,14/04/2020 08:34,,71–78,,,,,,,SEHC '11,,,,ACM,"New York, NY, USA",,,,,,,,,,,,medical education; simulation-based training; virtual worlds; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XLDEEFAE,conferencePaper,2011,"Murphy, Christian; Raunak, M. S.; King, Andrew; Chen, Sanjian; Imbriano, Christopher; Kaiser, Gail; Lee, Insup; Sokolsky, Oleg; Clarke, Lori; Osterweil, Leon",On Effective Testing of Health Care Simulation Software,Proceedings of the 3rd Workshop on Software Engineering in Health Care,978-1-4503-0585-3,,10.1145/1987993.1988003,http://doi.acm.org/10.1145/1987993.1988003,,2011,13/11/2018 10:47,14/04/2020 08:35,,40–47,,,,,,,SEHC '11,,,,ACM,"New York, NY, USA",,,,,,,,,,,,metamorphic testing; oracle problem; software testing; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, T2L4YBQN,conferencePaper,2011,"Merrick, Kathryn E.",A Computational Model of Achievement Motivation for Artificial Agents,The 10th International Conference on Autonomous Agents and Multiagent Systems - Volume 3,0-9826571-7-X 978-0-9826571-7-1,,,http://dl.acm.org/citation.cfm?id=2034396.2034421,,2011,13/11/2018 10:47,14/04/2020 08:34,,1067–1068,,,,,,,AAMAS '11,,,,International Foundation for Autonomous Agents and Multiagent Systems,"Richland, SC",,,,,,,,,,,,achievement motivation; autonomous mental development; cognitive agents; computational models of motivation; virtual agents; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GL5KQFKP,journalArticle,2011,"Hoffmann, Leah",Data Optimization in Developing Nations,Commun. ACM,,0001-0782,10.1145/1941487.1941495,http://doi.acm.org/10.1145/1941487.1941495,,2011-05,13/11/2018 10:47,14/04/2020 08:34,,18–20,,5,54,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, I43T35W7,conferencePaper,2011,"Diaz, Rafael; Behr, Joshua; Tulpule, Mandar",Energy Portfolio Simulation Considering Environmental and Public Health Impacts,Proceedings of the 2011 Emerging M&S Applications in Industry and Academia Symposium,,,,http://dl.acm.org/citation.cfm?id=2048513.2048522,,2011,13/11/2018 10:47,14/04/2020 08:34,,38–45,,,,,,,EAIA '11,,,,Society for Computer Simulation International,"San Diego, CA, USA",,,,,,,,,"

Emerging M and S Applications in Industry and Academia Symposium (EAIA 2011) / Spring Simulation Multiconference (SpringSim `11), Boston, MA, APR 03-07, 2011

",,,public health; simulation; system dynamics; energy portfolio; environmental pollution; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YG8DJK98,conferencePaper,2011,"Kounev, Samuel; Bender, Konstantin; Brosig, Fabian; Huber, Nikolaus; Okamoto, Russell",Automated Simulation-based Capacity Planning for Enterprise Data Fabrics,Proceedings of the 4th International ICST Conference on Simulation Tools and Techniques,978-1-936968-00-8,,,http://dl.acm.org/citation.cfm?id=2151054.2151060,,2011,13/11/2018 10:47,14/04/2020 08:34,,27–36,,,,,,,SIMUTools '11,,,,"ICST (Institute for Computer Sciences, Social-Informatics and Telecommunications Engineering)","ICST, Brussels, Belgium, Belgium",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8X7HH6BF,conferencePaper,2010,"Barnes, Sean; Golden, Bruce; Wasil, Edward",A Dynamic Patient Network Model of Hospital-acquired Infections,Proceedings of the Winter Simulation Conference,978-1-4244-9864-2,,,http://dl.acm.org/citation.cfm?id=2433508.2433785,,2010,13/11/2018 10:47,14/04/2020 08:34,,2249–2260,,,,,,,WSC '10,,,,Winter Simulation Conference,"Baltimore, Maryland",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RFNSPNK4,conferencePaper,2010,"Ismail, Khaled; Abo-Hamad, Waleed; Arisha, Amr",Integrating Balanced Scorecard and Simulation Modeling to Improve Emergency Department Performance in Irish Hospitals,Proceedings of the Winter Simulation Conference,978-1-4244-9864-2,,,http://dl.acm.org/citation.cfm?id=2433508.2433797,"In the healthcare sector, there is a requirement for innovative solutions in managing the high levels of complexity and uncertainty within Emergency Departments (EDs). Simulation modeling is currently seen as a competent means of analyzing EDs, which allows changes effects to be understood and predicted more easily. The Balanced Scorecard (BSC), well-known performance management concept, has become a steering method in approaching new improvement cycles. This paper presents a methodology that integrates BSC and simulation modeling to improve the performance of ED in a University Hospital in North Dublin. BSC design began with understanding patient's needs, ED activities, as well as training and development programs. Then a detailed simulation model was developed and integrated with the BSC to provide a comprehensive decision support system. This integrated model can be used for evaluation of various decisions in emergency area. The developed integrated model is also a tool for improvement.",2010,13/11/2018 10:47,14/04/2020 08:34,,2340–2351,,,,,,,WSC '10,,,,Winter Simulation Conference,"Baltimore, Maryland",,,,,,,,,,,,1; agent based; 310,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 64XDT27G,conferencePaper,2010,"Lizon, Natalia E.; Aleman, Dionne M.; Schwartz, Brian",Incorporating Healthcare Systems in Pandemic Models,Proceedings of the Winter Simulation Conference,978-1-4244-9864-2,,,http://dl.acm.org/citation.cfm?id=2433508.2433782,"There are several models used to predict the spread of disease in apandemic, but few, if any, incorporate the effect of healthcare systems in preventing propagation of the disease. In areas where healthcare is easily available to the general public (specifically, countries with universal healthcare), the ability of infected individuals to receive rapid treatment should impact disease spread. Additionally, the presence of a pandemic will result in an increased load on the healthcare system as infected individuals seek medical attention at hospitals and from their family doctors. We modify an existing non-homogeneous, agent-based simulation pandemic disease spread model to incorporate a public healthcare system in a pandemic influenza simulation on the Greater Toronto Area, Ontario, Canada. Results show that healthcare availability significantly significantly increases disease spread due to increased contacts within the population. We also find that the creation of flu centers decreases flu-related deaths and decreases hospital admissions.",2010,13/11/2018 10:47,14/04/2020 08:34,,2230–2236,,,,,,,WSC '10,,,,Winter Simulation Conference,"Baltimore, Maryland",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CUFFBJHE,conferencePaper,2010,"Charfeddine, Moez; Montreuil, Benoit",Integrated Agent-oriented Modeling and Simulation of Population and Healthcare Delivery Network: Application to COPD Chronic Disease in a Canadian Region,Proceedings of the Winter Simulation Conference,978-1-4244-9864-2,,,http://dl.acm.org/citation.cfm?id=2433508.2433794,"In this paper we introduce a framework for integrated agent-oriented modeling and simulation of the population with a specific chronic disease in a large region and of the network providing relevant healthcare services for this population. We illustrate the framework through the Chronic Obstructive Pulmonary Disease (COPD) population and healthcare delivery network in Quebec's capital region of Canada. In this framework exploiting agent oriented modeling, demand for healthcare is expressed deeply through the stochastic modeling of health status evolution of each person in a population of potential patients, where the implications of this evolution generate the demand in terms of patient needs for healthcare and their frequency. In parallel, the organization and functioning of the healthcare delivery network is modeled with an adequate detail level. This is made possible by exploiting the richness of the agent paradigm and by introducing integration mechanisms binding the two model components.",2010,13/11/2018 10:47,14/04/2020 08:34,,2327–2339,,,,,,,WSC '10,,,,Winter Simulation Conference,"Baltimore, Maryland",,,,,,,,,"

2010 Winter Simulation Conference, Baltimore, MD, DEC 05-08, 2010

",,,1; Agent Based; 420,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, B6UBIPCF,conferencePaper,2010,"Jahangirian, Mohsen; Taylor, Simon J. E.; Young, Terry",Economics of Modeling and Simulation: Reflections and Implications for Healthcare,Proceedings of the Winter Simulation Conference,978-1-4244-9864-2,,,http://dl.acm.org/citation.cfm?id=2433508.2433789,"Arguably, it is widely known that there is much activity in modeling & simulation (M&S) in healthcare, particularly in decision support and analysis for care delivery systems (CDS). This is supported by recent literature surveys. However, there is limited evidence of reported cost, success and impact. To attempt to investigate the so-called 'economics' of M&S in this area, this paper aims to depict a general picture of the economics of M&S supported by available evidence and to develop an initial set of guidelines using a novel framework that may assist decision makers in assessing the usefulness and cost-effectiveness of M&S. Our paper concludes with an urgent call for research in this area, specifically in terms of using standardized qualitative and quantitative methods to gather evidence for analysis and dissemination materials that 'speak' to government-level policy makers.",2010,13/11/2018 10:47,14/04/2020 08:34,,2283–2292,,,,,,,WSC '10,,,,Winter Simulation Conference,"Baltimore, Maryland",,,,,,,,,,,,1; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5P5EPNUS,conferencePaper,2010,"Gavrishchaka, Valeriy V.; Koepke, Mark E.; Ulyanova, Olga N.",Boosting-based Discovery of Multi-component Physiological Indicators: Applications to Express Diagnostics and Personalized Treatment Optimization,Proceedings of the 1st ACM International Health Informatics Symposium,978-1-4503-0030-8,,10.1145/1882992.1883111,http://doi.acm.org/10.1145/1882992.1883111,,2010,13/11/2018 10:47,14/04/2020 08:34,,790–799,,,,,,,IHI '10,,,,ACM,"New York, NY, USA",,,,,,,,,,,,boosting; ensemble learning algorithms; express diagnostics; heart rate variability; model combination; nonlinear dynamics; personalized and sport medicine; physiological modeling; rr time series; therapy optimization; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PQGJ8T4F,conferencePaper,2010,"Suhonen, Katja; Väätäjä, Heli",Assessing the Applicability of Modular Playability Heuristics for Evaluating Health-enhancing Games,Proceedings of the 14th International Academic MindTrek Conference: Envisioning Future Media Environments,978-1-4503-0011-7,,10.1145/1930488.1930519,http://doi.acm.org/10.1145/1930488.1930519,,2010,13/11/2018 10:47,14/04/2020 08:35,,147–150,,,,,,,MindTrek '10,,,,ACM,"New York, NY, USA",,,,,,,,,,,,health; education; exercise; games; heuristics; playability; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UPDMDWVA,conferencePaper,2010,"Noshadi, Hyduke; Dabiri, Foad; Meguerdichian, Saro; Potkonjak, Miodrag; Sarrafzadeh, Majid",Energy Optimization in Wireless Medical Systems Using Physiological Behavior,Wireless Health 2010,978-1-60558-989-3,,10.1145/1921081.1921097,http://doi.acm.org/10.1145/1921081.1921097,,2010,13/11/2018 10:47,14/04/2020 08:35,,128–136,,,,,,,WH '10,,,,ACM,"New York, NY, USA",,,,,,,,,,,,behavioral sensing; energy optimization; sensor selection; wearable medical systems; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YDMR9DWJ,conferencePaper,2010,"Kim, Taehyong; Ramanathan, Murali; Zhang, Aidong",A Graph-based Approach for Computational Model of Bone Microstructure,Proceedings of the First ACM International Conference on Bioinformatics and Computational Biology,978-1-4503-0438-2,,10.1145/1854776.1854883,http://doi.acm.org/10.1145/1854776.1854883,,2010,13/11/2018 10:47,14/04/2020 08:34,,563–568,,,,,,,BCB '10,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, F7QYXSWY,conferencePaper,2010,"Durand, Audrey; Gagné, Christian; Gardner, Marc-André; Rousseau, François; Giguère, Yves; Reinharz, Daniel",SCHNAPS: A Generic Population-based Simulator for Public Health Purposes,Proceedings of the 2010 Summer Computer Simulation Conference,,,,http://dl.acm.org/citation.cfm?id=1999416.1999438,"In this paper, we present SCHNAPS, a generic simulator designed for health care modelling and simulations, parametrizable by configuration files and usable by non-programmers such as public health specialists. SCHNAPS is a population-based simulator, using hybrid-state agents to simulate time-driven models. Its software architecture integrates some fundamental object oriented concepts to facilitate further developments and extensions. The proposed approach aims at narrowing the gap between the simulation model and the conceptual modelling made by public health specialists. Current work on osteoporosis, under evaluation by health care specialists, is also presented as a real use case",2010,13/11/2018 10:47,14/04/2020 08:34,,182–189,,,,,,,SCSC '10,,,,Society for Computer Simulation International,"San Diego, CA, USA",,,,,,,,,,,,1; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JL3AX7YR,conferencePaper,2010,"Zechman, Emily M.",Integrating Complex Adaptive System Simulation and Evolutionary Computation to Support Water Infrastructure Threat Management,Proceedings of the 12th Annual Conference Companion on Genetic and Evolutionary Computation,978-1-4503-0073-5,,10.1145/1830761.1830807,http://doi.acm.org/10.1145/1830761.1830807,,2010,13/11/2018 10:47,14/04/2020 08:35,,1809–1816,,,,,,,GECCO '10,,,,ACM,"New York, NY, USA",,,,,,,,,,,,agent-based modeling; threat management; water distribution security; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NDPVNWLI,conferencePaper,2010,"Koufi, V.; Malamateniou, F.; Vassilacopoulos, G.",An Agent-based Application of Personal Health Record in Homecare,Proceedings of the 3rd International Conference on PErvasive Technologies Related to Assistive Environments,978-1-4503-0071-1,,10.1145/1839294.1839309,http://doi.acm.org/10.1145/1839294.1839309,"Homecare is an important component of the continuum of care as it provides the potential to improve quality of life and quality of healthcare delivery while containing costs. Personal Health Record (PHR) systems constitute a technological infrastructure that can support greater flexibility for healthcare professionals and patients, thus allowing for more effective homecare services. In particular, PHRs are intended to reach patients outside of care settings, influence their behaviors, and satisfy their demand for greater information and access. To this end, PHR technology needs to evolve well beyond providing a consolidated patient record, in ways that make it more widely applicable and valuable to health systems. The development of applications and tools on top of PHR systems can allow the PHR to function as a platform for patients to exchange information and interact with the health system (e.g., scheduling appointments electronically). This paper presents a prototype PHR-based system that aims at supporting chronic disease management. The system has been developed on the grounds of a service-oriented architecture where healthcare process automation is realized by means of dynamic, patient-related workflows.",2010,13/11/2018 10:47,14/04/2020 08:34,,12:1–12:6,,,,,,,PETRA '10,,,,ACM,"New York, NY, USA",,,,,,,,,,,,homecare; personal health record; software agents; workflow systems; 1; agent based; 320,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, C8NUH5JV,conferencePaper,2010,"Huang, Yuxia",Modeling the Severe Acute Respiratory Syndrome (SARS) Outbreak in Beijing: An Agent-based Approach,Proceedings of the 1st International Conference and Exhibition on Computing for Geospatial Research & Application,978-1-4503-0031-5,,10.1145/1823854.1823895,http://doi.acm.org/10.1145/1823854.1823895,,2010,13/11/2018 10:47,14/04/2020 08:34,,36:1–36:4,,,,,,,COM.Geo '10,,,,ACM,"New York, NY, USA",,,,,,,,,,,,agent-based model; SARS; spatial-temporal simulation; 00; ******To read; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LWDBYZ3V,conferencePaper,2010,"Arshad, Naveed; Akhtar, Ambreen; Khan, Sohaib; Durr-e-Sabih",Software Engineering for Simulation Systems in Medical Training: Some Initial Experiences,Proceedings of the 2010 ICSE Workshop on Software Engineering in Health Care,978-1-60558-973-2,,10.1145/1809085.1809098,http://doi.acm.org/10.1145/1809085.1809098,,2010,13/11/2018 10:47,14/04/2020 08:34,,100–103,,,,,,,SEHC '10,,,,ACM,"New York, NY, USA",,,,,,,,,,,,health education; simulation system; ultrasound; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2DT8SF3B,conferencePaper,2010,"Loseu, Vitali; Ghasemzadeh, Hassan; Jafari, Roozbeh",Toward Power Optimization for Communication Failure Recovery in Body Sensor Networks,Proceedings of the 1st ACM/IEEE International Conference on Cyber-Physical Systems,978-1-4503-0066-7,,10.1145/1795194.1795222,http://doi.acm.org/10.1145/1795194.1795222,,2010,13/11/2018 10:47,14/04/2020 08:34,,198–198,,,,,,,ICCPS '10,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 749NEKVM,conferencePaper,2010,"Gibbs, Jonathan D.; Sarjoughian, Hessam S.",Synchronizing DEVS/SOA Simulator with Ping Monitoring Application,Proceedings of the 2010 Spring Simulation Multiconference,978-1-4503-0069-8,,10.1145/1878537.1878682,https://doi.org/10.1145/1878537.1878682,,2010,13/11/2018 10:47,14/04/2020 08:34,,139:1–139:7,,,,,,,SpringSim '10,,,,Society for Computer Simulation International,"San Diego, CA, USA",,,,,,,,,,,,DEVS/SOA; ping; synchronization; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VRDADWI2,conferencePaper,2010,"Koizumi, Yoshinori; Nishida, Yoshifumi; Motomura, Yoichi; Miyazaki, Yusuke; Mizoguchi, Hiroshi",Presenting Potential Injury Risk by Biomechanical Simulation Based on Bodygraphic Injury Data,Proceedings of the 3rd International ICST Conference on Simulation Tools and Techniques,978-963-9799-87-5,,10.4108/ICST.SIMUTOOLS2010.8732,https://doi.org/10.4108/ICST.SIMUTOOLS2010.8732,,2010,13/11/2018 10:47,14/04/2020 08:34,,76:1–76:6,,,,,,,SIMUTools '10,,,,"ICST (Institute for Computer Sciences, Social-Informatics and Telecommunications Engineering)","ICST, Brussels, Belgium, Belgium",,,,,,,,,,,,hazard identification; impact biomechanics; injury informatics; injury prevention; injury surveillance; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9SS6JYYF,conferencePaper,2010,"Gopalakrishnan, S.",Emergent Digital Value Chain Optimizing Software Spend,Proceedings of the 3rd India Software Engineering Conference,978-1-60558-922-0,,10.1145/1730874.1730876,http://doi.acm.org/10.1145/1730874.1730876,,2010,13/11/2018 10:47,14/04/2020 08:34,,111–112,,,,,,,ISEC '10,,,,ACM,"New York, NY, USA",,,,,,,,,,,,business process; digital value chain; information infrastructure; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RAW2P623,conferencePaper,2009,"Faller, Stephen L., III; Flynn, C. Tanner; Ferrin, David M.",Simulating Health Care in Prison Systems,Winter Simulation Conference,978-1-4244-5771-7,,,http://dl.acm.org/citation.cfm?id=1995456.1995735,,2009,13/11/2018 10:47,14/04/2020 08:34,,2032–2041,,,,,,,WSC '09,,,,Winter Simulation Conference,"Austin, Texas",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YDE9RX9Z,conferencePaper,2009,"Holm, Lene Berge; Dahl, Fredrik A.",Simulating the Effect of Physician Triage in the Emergency Department of Akershus University Hospital,Winter Simulation Conference,978-1-4244-5771-7,,,http://dl.acm.org/citation.cfm?id=1995456.1995718,,2009,13/11/2018 10:47,14/04/2020 08:34,,1896–1905,,,,,,,WSC '09,,,,Winter Simulation Conference,"Austin, Texas",,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8J6HHES4,conferencePaper,2009,"Rossetti, Manuel D.; Liu, Yanchao",Simulating SKU Proliferation in a Health Care Supply Chain,Winter Simulation Conference,978-1-4244-5771-7,,,http://dl.acm.org/citation.cfm?id=1995456.1995779,,2009,13/11/2018 10:47,14/04/2020 08:35,,2365–2374,,,,,,,WSC '09,,,,Winter Simulation Conference,"Austin, Texas",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3IUDS5JS,conferencePaper,2009,"Lee, Young M.; Ghosh, Soumyadip; Ettl, Markus",Simulating Distribution of Emergency Relief Supplies for Disaster Response Operations,Winter Simulation Conference,978-1-4244-5771-7,,,http://dl.acm.org/citation.cfm?id=1995456.1995837,,2009,13/11/2018 10:47,14/04/2020 08:34,,2797–2808,,,,,,,WSC '09,,,,Winter Simulation Conference,"Austin, Texas",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LBEWXDUY,conferencePaper,2009,"Brailsford, Sally C.; Bolt, Timothy; Connell, Con; Klein, Jonathan H.; Patel, Brijesh",Stakeholder Engagement in Health Care Simulation,Winter Simulation Conference,978-1-4244-5771-7,,,http://dl.acm.org/citation.cfm?id=1995456.1995711,"The RIGHT project (Research Into Global Healthcare Tools, http://www.right.org.uk/) is a collaborative project involving five British universities, funded by the UK's Engineering and Physical Sciences Research Council. Phase 1 of the project is due to be completed in October 2009, and this paper describes one strand of the research, namely identifying some of the issues with involving stakeholders in simulation modeling in healthcare. Not the least of these is actually identifying who the stakeholders are! Other problems identified are equally tricky, as they involve deeply rooted cultural and behavioral attitudes as well as complex organizational relationships. One of the underlying aims of the next phase of RIGHT is to tackle these problems and to develop a methodology for more effective stakeholder engagement with simulation modeling.",2009,13/11/2018 10:47,14/04/2020 08:34,,1840–1849,,,,,,,WSC '09,,,,Winter Simulation Conference,"Austin, Texas",,,,,,,,,,,,1; ******To read; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ZWEYS3TP,conferencePaper,2009,"Wynter, Sharolyn A.; Ivy, Julie E.",Simulating Public Health Emergency Response: A Case Study of the 2004 North Carolina State Fair E. Coli Outbreak,Winter Simulation Conference,978-1-4244-5771-7,,,http://dl.acm.org/citation.cfm?id=1995456.1995726,,2009,13/11/2018 10:47,14/04/2020 08:35,,1957–1968,,,,,,,WSC '09,,,,Winter Simulation Conference,"Austin, Texas",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JIQ4JW8Y,conferencePaper,2009,"Papageorgiou, Christos; Birkos, Konstantinos; Dagiuklas, Tasos; Kotsopoulos, Stavros",Simulating Mission Critical Mobile Ad Hoc Networks,Proceedings of the 4th ACM Workshop on Performance Monitoring and Measurement of Heterogeneous Wireless and Wired Networks,978-1-60558-621-2,,10.1145/1641913.1641934,http://doi.acm.org/10.1145/1641913.1641934,,2009,13/11/2018 10:47,14/04/2020 08:35,,143–150,,,,,,,PM2HW2N '09,,,,ACM,"New York, NY, USA",,,,,,,,,,,,ad hoc networks; mission critical; mobility model; ns-2; obstacles; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, AWAVDUES,conferencePaper,2009,"Bisset, Keith R.; Chen, Jiangzhuo; Feng, Xizhou; Kumar, V.S. Anil; Marathe, Madhav V.",EpiFast: A Fast Algorithm for Large Scale Realistic Epidemic Simulations on Distributed Memory Systems,Proceedings of the 23rd International Conference on Supercomputing,978-1-60558-498-0,,10.1145/1542275.1542336,http://doi.acm.org/10.1145/1542275.1542336,,2009,13/11/2018 10:47,14/04/2020 08:34,,430–439,,,,,,,ICS '09,,,,ACM,"New York, NY, USA",,,,,,,,,,,,simulation; epidemics; distributed memory; parallel algorithm; seir; social contact network; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BJU45GBI,conferencePaper,2009,"Temime, Laura; Pannet, Yohan; Kardas, Lidia; Opatowski, Lulla; Guillemot, Didier; Boëlle, Pierre-Yves",NOSOSIM: An Agent-based Model of Pathogen Circulation in a Hospital Ward,Proceedings of the 2009 Spring Simulation Multiconference,,,,http://dl.acm.org/citation.cfm?id=1639809.1639819,,2009,13/11/2018 10:47,14/04/2020 08:35,,9:1–9:8,,,,,,,SpringSim '09,,,,Society for Computer Simulation International,"San Diego, CA, USA",,,,,,,,,,,,epidemiology; agent-based modeling; hospital; MRSA; nosocomial infections; VRE; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 466E4ILB,conferencePaper,2008,"Khurma, Nancy; Bacioiu, Gheorghe M.; Pasek, Zbigniew J.",Simulation-based Verification of Lean Improvement for Emergency Room Process,Proceedings of the 40th Conference on Winter Simulation,978-1-4244-2708-6,,,http://dl.acm.org/citation.cfm?id=1516744.1517006,,2008,13/11/2018 10:47,14/04/2020 08:34,,1490–1499,,,,,,,WSC '08,,,,Winter Simulation Conference,"Miami, Florida",,,,,,,,,,,,1; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ZWLGQ7SA,conferencePaper,2008,"Lee, Young M.",Analyzing Dispensing Plan for Emergency Medical Supplies in the Event of Bioterrorism,Proceedings of the 40th Conference on Winter Simulation,978-1-4244-2708-6,,,http://dl.acm.org/citation.cfm?id=1516744.1517201,,2008,13/11/2018 10:47,14/04/2020 08:34,,2600–2608,,,,,,,WSC '08,,,,Winter Simulation Conference,"Miami, Florida",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WFA98KHR,conferencePaper,2008,"Giachetti, Ronald E.",A Simulation Study of Interventions to Reduce Appointment Lead-time and Patient No-show Rate,Proceedings of the 40th Conference on Winter Simulation,978-1-4244-2708-6,,,http://dl.acm.org/citation.cfm?id=1516744.1517001,"A problem in health care is the lengthy waiting time for patients to receive an appointment. Long appointment delays cause patient dissatisfaction with the health care clinic and also has clinical ramifications. Long appointment delays are also found to increase patient no-shows, which further wastes medical resources and leads to a decrease in clinical care. A model of the health care clinic is built to understand the casual relationships in the system contributing to the problem. The model is used to investigate two possible policies. A policy of eliminating multiple appointment types can be effective in reducing appointment delay and as a consequent no-shows. Using data from several clinics, our study also suggests that an effective policy is to segregate habitual no-show patients and double-book them whenever they make appointments. This policy is equally effective as general overbooking without penalizing the entire patient population.",2008,13/11/2018 10:47,14/04/2020 08:34,,1463–1468,,,,,,,WSC '08,,,,Winter Simulation Conference,"Miami, Florida",,,,,,,,,,,,System dynamics; 1; 310,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LE56LBQQ,conferencePaper,2008,"Bauer, David W., Jr.; Mohtashemi, Mojdeh",An Application of Parallel Monte Carlo Modeling for Real-time Disease Surveillance,Proceedings of the 40th Conference on Winter Simulation,978-1-4244-2708-6,,,http://dl.acm.org/citation.cfm?id=1516744.1516927,,2008,13/11/2018 10:47,14/04/2020 08:34,,1029–1037,,,,,,,WSC '08,,,,Winter Simulation Conference,"Miami, Florida",,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, N3IIC5JN,conferencePaper,2008,"Chahal, Kirandeep; Eldabi, Tillal",Applicability of Hybrid Simulation to Different Modes of Governance in UK Healthcare,Proceedings of the 40th Conference on Winter Simulation,978-1-4244-2708-6,,,http://dl.acm.org/citation.cfm?id=1516744.1517002,"Healthcare organizations exhibit both detailed and dynamic complexity. Effective and sustainable decision-making in healthcare requires tools that can comprehend this complexity. Discrete event simulation (DES) due to its ability to capture detail complexity is widely used for operational decision making. However at the strategic level, System Dynamics (SD) with its focus on a holistic perspective and its ability to comprehend dynamic complexity has advantages over DES. Appreciating the complexity of healthcare, the authors have proposed the use of hybrid simulation in healthcare. As argued previously, effective decision making require tools which are capable of comprehending both detail and dynamic interactions of healthcare. The interactions in the organizations are governed by the governance design. In appreciation of that argument the authors have described the applicability of a hybrid approach to various modes of governance in UK healthcare.",2008,13/11/2018 10:47,14/04/2020 08:34,,1469–1477,,,,,,,WSC '08,,,,Winter Simulation Conference,"Miami, Florida",,,,,,,,,,,,210; Hybrid Simulation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UX378IZG,conferencePaper,2008,"Yaesoubi, Reza; Roberts, Stephen D.",How Much is a Health Insurer Willing to Pay for Colorectal Cancer Screening Tests?,Proceedings of the 40th Conference on Winter Simulation,978-1-4244-2708-6,,,http://dl.acm.org/citation.cfm?id=1516744.1517029,,2008,13/11/2018 10:47,14/04/2020 08:35,,1624–1631,,,,,,,WSC '08,,,,Winter Simulation Conference,"Miami, Florida",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RGMEXDPT,conferencePaper,2008,"Cowan, Brent; Shelley, Matthew; Sabri, Hamed; Kapralos, Bill; Hogue, Andrew; Hogan, Michelle; Jenkin, Michael; Goldsworthy, Sandra; Rose, Louise; Dubrowski, Adam",Interprofessional Care Simulator for Critical Care Education,"Proceedings of the 2008 Conference on Future Play: Research, Play, Share",978-1-60558-218-4,,10.1145/1496984.1497043,http://doi.acm.org/10.1145/1496984.1497043,,2008,13/11/2018 10:47,14/04/2020 08:34,,260–261,,,,,,,Future Play '08,,,,ACM,"New York, NY, USA",,,,,,,,,,,,active learning; interporfessional education; serious games; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EG7IN2BJ,conferencePaper,2008,"Liang, Yun; Ju, Lei; Chakraborty, Samarjit; Mitra, Tulika; Roychoudhury, Abhik",Cache-aware Optimization of BAN Applications,Proceedings of the 6th IEEE/ACM/IFIP International Conference on Hardware/Software Codesign and System Synthesis,978-1-60558-470-6,,10.1145/1450135.1450170,http://doi.acm.org/10.1145/1450135.1450170,,2008,13/11/2018 10:47,14/04/2020 08:34,,149–154,,,,,,,CODES+ISSS '08,,,,ACM,"New York, NY, USA",,,,,,,,,,,,mobile devices; body-area networks; cache; sensor networks; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7HTYS3VN,conferencePaper,2008,"Shopf, Jeremy; Barczak, Joshua; Oat, Christopher; Tatarchuk, Natalya",March of the Froblins: Simulation and Rendering Massive Crowds of Intelligent and Detailed Creatures on GPU,ACM SIGGRAPH 2008 Games,,,10.1145/1404435.1404439,http://doi.acm.org/10.1145/1404435.1404439,,2008,13/11/2018 10:47,14/04/2020 08:35,,52–101,,,,,,,SIGGRAPH '08,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2C7RPBZS,conferencePaper,2008,"Pasdirtz, George W.",Technology and the Health Care Quadrilemma: A Test,Proceedings of the 2008 Spring Simulation Multiconference,1-56555-319-5,,,http://dl.acm.org/citation.cfm?id=1400549.1400623,,2008,13/11/2018 10:47,14/04/2020 08:35,,491–496,,,,,,,SpringSim '08,,,,Society for Computer Simulation International,"San Diego, CA, USA",,,,,,,,,,,,counterfactual history; health care quadrillema; state-space models; technology; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XNISRJ52,conferencePaper,2008,"Li, Jiahua; Zhou, Yue; Ishino, Fukuya",Using Simulation to Improve Outpatient Appointment System with Minimum Change,Proceedings of the 2008 Spring Simulation Multiconference,1-56555-319-5,,,http://dl.acm.org/citation.cfm?id=1400549.1400626,,2008,13/11/2018 10:47,14/04/2020 08:34,,507–512,,,,,,,SpringSim '08,,,,Society for Computer Simulation International,"San Diego, CA, USA",,,,,,,,,,,,outpatient; appointment system; clinic; scheduling; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QJF4QQUF,conferencePaper,2008,"Ghasemzadeh, Hassan; Guenterberg, Eric; Gilani, Katherine; Jafari, Roozbeh",Action Coverage Formulation for Power Optimization in Body Sensor Networks,Proceedings of the 2008 Asia and South Pacific Design Automation Conference,978-1-4244-1922-7,,,http://dl.acm.org/citation.cfm?id=1356802.1356911,,2008,13/11/2018 10:47,14/04/2020 08:34,,446–451,,,,,,,ASP-DAC '08,,,,IEEE Computer Society Press,"Los Alamitos, CA, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Y69X6Q7A,conferencePaper,2007,"Davies, Ruth","""See and Treat"" or ""See"" and ""Treat"" in an Emergency Department",Proceedings of the 39th Conference on Winter Simulation: 40 Years! The Best is Yet to Come,1-4244-1306-0,,,http://dl.acm.org/citation.cfm?id=1351542.1351811,,2007,13/11/2018 10:47,14/04/2020 08:34,,1519–1522,,,,,,,WSC '07,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 66BVJEFV,conferencePaper,2007,"Miller, Martin; Ferrin, David; Ashby, Marshall; Flynn, Tanner; Shahi, Niloo",Merging Six Emergency Departments into One: A Simulation Approach,Proceedings of the 39th Conference on Winter Simulation: 40 Years! The Best is Yet to Come,1-4244-1306-0,,,http://dl.acm.org/citation.cfm?id=1351542.1351824,"Simulation of existing systems can reinforce a Subject Matter Expert's gut feelings. However, it is more difficult to develop intuition for proposed systems, particularly when considering the consolidation of multiple systems. This paper discusses the use of simulation to determine the operational ramifications of combining six Emergency Departments into one of the largest in the country. Each of these six existing Emergency Departments serve a different type of patient population and each maintains their own independent processes. This hospital required all Emergency Departments to effectively function using the same floor space, processes and ancillary services, such as testing facilities, waiting rooms, and registration. Healthcare planners need to understand the ramifications of sharing resources among multiple departments and the operational impact of high volume systems. This project explored these challenges to find key bottlenecks and mitigation strategies using simulation.",2007,13/11/2018 10:47,14/04/2020 08:34,,1574–1578,,,,,,,WSC '07,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; ******To read; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YZ7DJIXS,conferencePaper,2007,"Chi, Hongmei; Zhao, Lang",A Conceptual Model to Support the Integration of Inter-organizational Healthcare Information Systems,Proceedings of the 39th Conference on Winter Simulation: 40 Years! The Best is Yet to Come,1-4244-1306-0,,,http://dl.acm.org/citation.cfm?id=1351542.1351968,"The inability to share information across systems is just one of the major impediments in the health care business that hinders progress towards efficiency and cost-effectiveness. This poster investigates workflow involvement of healthcare process in order to support and complement the transition of information and tasks among different healthcare organizations. This research examined dataflow between organizations. The purpose of this study is to propose a conceptual model for integrating healthcare information systems of various healthcare organizations. A case study among pharmacy, hospital and clinic is presented in this paper. Our experimental results show that this model is scalable and it can be easier to extend to pervasive computing environment. Petri net is the primary method for this model.",2007,13/11/2018 10:47,14/04/2020 08:34,,2368–2368,,,,,,,WSC '07,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5BK227SY,conferencePaper,2007,"Tayfur, Esengul; Taaffe, Kevin",Allocation of Resources for Hospital Evacuations via Simulation,Proceedings of the 39th Conference on Winter Simulation: 40 Years! The Best is Yet to Come,1-4244-1306-0,,,http://dl.acm.org/citation.cfm?id=1351542.1351742,,2007,13/11/2018 10:47,14/04/2020 08:35,,1148–1154,,,,,,,WSC '07,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TN8GRPRX,conferencePaper,2007,"Gunal, Murat M.; Pidd, Michael","Interconnected DES Models of Emergency, Outpatient, and Inpatient Departments of a Hospital",Proceedings of the 39th Conference on Winter Simulation: 40 Years! The Best is Yet to Come,1-4244-1306-0,,,http://dl.acm.org/citation.cfm?id=1351542.1351800,"National Health Service (NHS) performance targets in England have put pressure on hospital management to reduce waiting times. The stochastic nature of emergency patient arrivals creates problems for capacity planning for elective patients. We present a whole hospital model which can be used at policy level to investigate cause and effect relations, such as effects of increased emergency arrival volumes on elective waiting times. A typical general hospital can be abstracted in three main units; Accident and Emergency (A&E) department, outpatient clinics, and inpatient units. In real life these units are coupled and share hospital resources. We developed three discrete event simulation (DES) models for each unit to form a whole hospital DES model. We present our models conceptually and our main discussion is on the level of detail in these three models.",2007,13/11/2018 10:47,14/04/2020 08:34,,1461–1466,,,,,,,WSC '07,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,discrete event simulation; 1; 310,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7ZJSBQNN,conferencePaper,2007,"Kale, Neelesh; Zottolo, Marcelo; Ülgen, Onur M.; Williams, Edward J.",Simulation Improves End-of-line Sortation and Material Handling Pickup Scheduling at Appliance Manufacturer,Proceedings of the 39th Conference on Winter Simulation: 40 Years! The Best is Yet to Come,1-4244-1306-0,,,http://dl.acm.org/citation.cfm?id=1351542.1351875,,2007,13/11/2018 10:47,14/04/2020 08:34,,1863–1868,,,,,,,WSC '07,,,,IEEE Press,"Piscataway, NJ, USA",,,,,,,,,,,,100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, J3GHPU9J,journalArticle,2007,"Kopec, Danny; Tamang, Suzanne","Failures in Complex Systems: Case Studies, Causes, and Possible Remedies",SIGCSE Bull.,,0097-8418,10.1145/1272848.1272905,http://doi.acm.org/10.1145/1272848.1272905,"Computers are the pervasive technology of our time. As computers become critically tied to human life, it also becomes more important that interactions with them are under control. They are no longer a novelty, but are integrated into the fabric of our world, performing both high and low-level tasks. That is, computers may be used to eliminate heavy, redundant work and more sophisticated machines have been deployed to perform remote surgery or detect subterranean landmines in repopulated civilian areas. The increasing importance of computers in our lives means that it is essential that the design of computer systems incorporates techniques that can ensure reliability, safety, and security. This paper will examine technological mishaps involving the use of computers. This review will include notorious software bugs that have affected finance, communication, transit, defense, health and medicine and other systems or industries. The sequences and etiology of these ""accidents"" will be discussed as well as how catastrophes may be avoided in the future through lessons and practices based on artificial intelligence research.",2007-06,13/11/2018 10:47,14/04/2020 08:34,,180–184,,2,39,,,,,,,,,,,,,,,,,,,,,complex systems; human errors; medical errors; safety-critical systems; software bugs; software engineering; technical disasters; 1; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5UELLWH6,conferencePaper,2006,"Mustafee, Navonil; Taylor, Simon J. E.; Katsaliaki, Korina; Brailsford, Sally",Distributed Simulation with COTS Simulation Packages: A Case Study in Health Care Supply Chain Simulation,Proceedings of the 38th Conference on Winter Simulation,1-4244-0501-7,,,http://dl.acm.org/citation.cfm?id=1218112.1218318,,2006,13/11/2018 10:47,14/04/2020 08:35,,1136–1142,,,,,,,WSC '06,,,,Winter Simulation Conference,"Monterey, California",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RDNFLFNF,conferencePaper,2006,"Gunal, Murat M.; Pidd, Michael",Understanding Accident and Emergency Department Performance Using Simulation,Proceedings of the 38th Conference on Winter Simulation,1-4244-0501-7,,,http://dl.acm.org/citation.cfm?id=1218112.1218197,"As part of a larger project examining the effect of performance targets on UK hospitals, we present a simulation of an Accident and Emergency (A&E) Department. Performance targets are an important part of the National Health Service (NHS) performance assessment regime in the UK. Pressures on A&Es force the medical staff to take actions meeting these targets with limited resources. We used simulation modelling to help understand the factors affecting this performance. We utilized real data from patient admission system of an A&E and presented some data analysis. Our particular focuses are the multitasking behaviour and experience level of medical staff, both of which affect A&E performance. This performance affects, in turn, the overall performance of the hospital of which it is part.",2006,13/11/2018 10:47,14/04/2020 08:34,,446–452,,,,,,,WSC '06,,,,Winter Simulation Conference,"Monterey, California",,,,,,,,,,,,1; Discrete event; 310,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UEJCQJ7G,conferencePaper,2006,"Patvivatsiri, Lisa",A Simulation Model for Bioterrorism Preparedness in an Emergency Room,Proceedings of the 38th Conference on Winter Simulation,1-4244-0501-7,,,http://dl.acm.org/citation.cfm?id=1218112.1218208,,2006,13/11/2018 10:47,14/04/2020 08:35,,501–508,,,,,,,WSC '06,,,,Winter Simulation Conference,"Monterey, California",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MA7CIQRB,conferencePaper,2006,"Ruohonen, Toni; Neittaanmäki, Pekka; Teittinen, Jorma",Simulation Model for Improving the Operation of the Emergency Department of Special Health Care,Proceedings of the 38th Conference on Winter Simulation,1-4244-0501-7,,,http://dl.acm.org/citation.cfm?id=1218112.1218198,"This paper presents a simulation model which describes the operations in the Emergency Department of Special Health Care at the Central Hospital of Jyväskylä, Finland. It can be used to test different process scenarios, allocate resources and perform activity based cost analysis. By using the simulation model we demonstrate a new operational method, which makes the operation of the Emergency Department of Special Health Care more effective. This operational method is called the triage-team method and it has been studied from two different points of view. The results showed that this method improves the operation of the Emergency Department of Special Health Care substantially (over 25%), if it is implemented properly and includes all the necessary tasks.",2006,13/11/2018 10:47,14/04/2020 08:34,,453–458,,,,,,,WSC '06,,,,Winter Simulation Conference,"Monterey, California",,,,,,,,,,,,00; Review,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, P2M63LN6,conferencePaper,2006,"Brailsford, Sally C.; Sykes, Jennifer; Harper, Paul R.",Incorporating Human Behavior in Healthcare Simulation Models,Proceedings of the 38th Conference on Winter Simulation,1-4244-0501-7,,,http://dl.acm.org/citation.cfm?id=1218112.1218201,"For many years, simulation has been used to evaluate the outcomes from medical interventions designed to improve patients' health. However in practice these outcomes can be greatly affected by patient behavior. For example, patients may not complete a course of a prescribed medication because they find the side-effects unpleasant. A study designed to evaluate this medication which ignores such behavioral factors may give unreliable results. In this paper we discuss some of the issues involved in incorporating human factors in simulation models, and we describe two models for screening for different diseases which have attempted to include behavioral factors.",2006,13/11/2018 10:47,14/04/2020 08:34,,466–472,,,,,,,WSC '06,,,,Winter Simulation Conference,"Monterey, California",,,,,,,,,,,,1; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MMVUN8YZ,conferencePaper,2005,"Koelling, Patrick; Schwandt, Michael J.",Health Systems: A Dynamic System—benefits from System Dynamics,Proceedings of the 37th Conference on Winter Simulation,0-7803-9519-0,,,http://dl.acm.org/citation.cfm?id=1162708.1162939,"Operations researchers, industrial engineers, and simulation analysts have applied their knowledge and skills to the health care system for a long time. This complex system needs their help today more than ever. The ever-growing need to understand and improve system performance challenges researchers to apply all the tools at their disposal. One of these tools that is getting increased attention is system thinking, with its application partner system dynamics. This paper presents a glimpse into the system thinking world as it is currently applied in the health care arena, and provides some thoughts on new directions for application. While there are other very useful tools, such as optimization and discrete-event simulation, that are effectively used for health care application, they should not always be the tools of choice, and suggestions are made for when system dynamics may be more appropriate for a particular application.",2005,13/11/2018 10:47,14/04/2020 08:34,,1321–1327,,,,,,,WSC '05,,,,Winter Simulation Conference,"Orlando, Florida",,,,,,,,,,,,System dynamics; 1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, S2X3EQCU,conferencePaper,2005,"White, K. Preston, Jr.",A Survey of Data Resources for Simulating Patient Flows in Healthcare Delivery Systems,Proceedings of the 37th Conference on Winter Simulation,0-7803-9519-0,,,http://dl.acm.org/citation.cfm?id=1162708.1162869,,2005,13/11/2018 10:47,14/04/2020 08:35,,926–935,,,,,,,WSC '05,,,,Winter Simulation Conference,"Orlando, Florida",,,,,,,,,,,,00; ******To read; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, W59TENTJ,conferencePaper,2005,"Spry, Charles W.; Lawley, Mark A.",Evaluating Hospital Pharmacy Staffing and Work Scheduling Using Simulation,Proceedings of the 37th Conference on Winter Simulation,0-7803-9519-0,,,http://dl.acm.org/citation.cfm?id=1162708.1163102,"With increasing healthcare costs, an aging population, and a shortage of trained personnel it is becoming increasingly important for hospital pharmacy management to make good operational decisions. In the case of hospital inpatient pharmacies, making decisions about staffing and work scheduling is difficult due to the complexity of the systems used and the variation in the orders to be filled. In order to help BroMenn Healthcare make decisions about staffing and work scheduling a simulation model was created to analyze the impact of alternate work schedules. The model estimates the effect of changes to staffing and work scheduling on the amount of time medication orders take to process. The goal is to use the simulation to help BroMenn find the best schedule to get medications to the patients as quickly as possible by using pharmacy staff effectively.",2005,13/11/2018 10:47,14/04/2020 08:35,,2256–2263,,,,,,,WSC '05,,,,Winter Simulation Conference,"Orlando, Florida",,,,,,,,,,,,00; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JE9M7YEJ,conferencePaper,2005,"Huang, Hsing-Jung; Chang, Ting-Hao; Hu, Shu-Yu; Huang, Polly",Magnetic Diffusion: Disseminating Mission-critical Data for Dynamic Sensor Networks,"Proceedings of the 8th ACM International Symposium on Modeling, Analysis and Simulation of Wireless and Mobile Systems",1-59593-188-0,,10.1145/1089444.1089468,http://doi.acm.org/10.1145/1089444.1089468,,2005,13/11/2018 10:47,14/04/2020 08:34,,134–141,,,,,,,MSWiM '05,,,,ACM,"New York, NY, USA",,,,,,,,,,,,data dissemination; sensor network; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9FEKGCD9,conferencePaper,2005,"Simmons, David R.; Edwards, Maura; MacPherson, Lorna M. D.; Stephen, Kenneth; McKerlie, Robert A.",The Simulation of Dental Fluorosis,Proceedings of the 2Nd Symposium on Applied Perception in Graphics and Visualization,1-59593-139-2,,10.1145/1080402.1080439,http://doi.acm.org/10.1145/1080402.1080439,,2005,13/11/2018 10:47,14/04/2020 08:35,,159–159,,,,,,,APGV '05,,,,ACM,"New York, NY, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BZ5D2AHD,conferencePaper,2004,"Sinreich, David; Marmor, Yariv N.",A Simple and Intuitive Simulation Tool for Analyzing Emergency Department Operations,Proceedings of the 36th Conference on Winter Simulation,0-7803-8786-4,,,http://dl.acm.org/citation.cfm?id=1161734.1162107,"In recent years hospitals have been vigorously searching for ways to reduce costs and improve productivity. One tool, simulation, is now widely accepted as an effective method for assisting management in evaluating different operational alternatives. It can help improve existing Emergency Departments (EDs) and assist in planning and designing new EDs. In order to increase the acceptance of simulation in healthcare systems in general and EDs in particular, hospital management should be directly involved in the development of these projects. Such involvement will also bolster the model's credibility. In addition, it is important to simplify simulation processes as much as is reasonably possible and use visual aids or animation that will heighten users' confidence in the model's ability. This study lays the foundation for the development of a simulation tool which is general, flexible, intuitive, simple to use and contains default values for most of the system's parameters.",2004,13/11/2018 10:47,14/04/2020 08:34,,1994–2002,,,,,,,WSC '04,,,,Winter Simulation Conference,"Washington, D.C.",,,,,,,,,,,,discrete event simulation; 1; 310,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4QG6HCJY,conferencePaper,2004,"Ramakrishnan, Sreekanth; Nagarkar, Kaustubh; DeGennaro, Monice; Srihari, Krishnaswami; Courtney, Andrea K.; Emick, Frank",A Study of the CT Scan Area of a Healthcare Provider,Proceedings of the 36th Conference on Winter Simulation,0-7803-8786-4,,,http://dl.acm.org/citation.cfm?id=1161734.1162112,,2004,13/11/2018 10:47,14/04/2020 08:35,,2025–2031,,,,,,,WSC '04,,,,Winter Simulation Conference,"Washington, D.C.",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WUJ2PF3C,conferencePaper,2004,"Pollak, Eytan; Falash, Mark; Ingraham, Lorie; Gottesman, Vivian",Operational Analysis Framework for Emergency Operations Center Preparedness Training,Proceedings of the 36th Conference on Winter Simulation,0-7803-8786-4,,,http://dl.acm.org/citation.cfm?id=1161734.1161888,,2004,13/11/2018 10:47,14/04/2020 08:35,,839–848,,,,,,,WSC '04,,,,Winter Simulation Conference,"Washington, D.C.",,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2S9XSKGF,conferencePaper,2003,"Morrison, Bradley P.; Bird, Barbara C.",Healthcare Process Analysis: A Methodology for Modeling Front Office and Patient Care Processes in Ambulatory Health Care,Proceedings of the 35th Conference on Winter Simulation: Driving Innovation,0-7803-8132-7,,,http://dl.acm.org/citation.cfm?id=1030818.1031078,,2003,13/11/2018 10:47,14/04/2020 08:35,,1882–1886,,,,,,,WSC '03,,,,Winter Simulation Conference,"New Orleans, Louisiana",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CEUQ7QSY,conferencePaper,2002,"Andrews, Gail; MacKinnon, Kimberley A.; Yoon, Susan","Using ""Thinking Tags"" with Kindergarten Children: A Dental Health Simulation",Proceedings of the Conference on Computer Support for Collaborative Learning: Foundations for a CSCL Community,,,,http://dl.acm.org/citation.cfm?id=1658616.1658740,,2002,13/11/2018 10:47,14/04/2020 08:34,,597–598,,,,,,,CSCL '02,,,,International Society of the Learning Sciences,"Boulder, Colorado",,,,,,,,,,,,technology; participatory simulation; dental health; discourse; science; thinking tags; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4Q2XALY7,conferencePaper,2001,"Alexopoulos, Christos; Goldsman, David; Fontanesi, John; Sawyer, Mark; De Guire, Michelle; Kopald, David; Holcomb, Kathy",Healthcare I: A Discrete-event Simulation Application for Clinics Serving the Poor,Proceedings of the 33Nd Conference on Winter Simulation,0-7803-7309-X,,,http://dl.acm.org/citation.cfm?id=564124.564326,"Healthcare management operates in an environment of aggressive pricing, tough competition, and rapidly changing guidelines. Computer simulation models are increasingly used by large healthcare institutions to meet these challenges. However, small healthcare facilities serving the poor are equally in need of meeting these challenges but lack the finances and personnel required to develop and implement their own simulation solutions. An academic medical center, healthcare facilities that serve the poor, and the local public health department formed a unique partnership to create low-cost tools to meet these challenges. This article describes the creation of a low-cost, generic, discrete-event simulation model populated by a workflow observation Excel spreadsheet that can be completed by clinic staff themselves, thus ""customizing"" the simulation model for their own purposes. This initial model focuses on childhood immunization delivery services; the intent is to develop a tool flexible enough to serve other health services delivery needs as well.",2001,13/11/2018 10:47,14/04/2020 08:34,,1386–1391,,,,,,,WSC '01,,,,IEEE Computer Society,"Washington, DC, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HP37EZLZ,conferencePaper,2000,"Baldwin, Lynne P.; Eldabi, Tillal; Paul, Ray J.; Burroughs, Andrew K.",Using Simulation for the Economic Evaluation of Liver Transplantation,Proceedings of the 32Nd Conference on Winter Simulation,0-7803-6582-8,,,http://dl.acm.org/citation.cfm?id=510378.510665,,2000,13/11/2018 10:47,14/04/2020 08:34,,1963–1970,,,,,,,WSC '00,,,,Society for Computer Simulation International,"San Diego, CA, USA",,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, SQTJPBLF,conferencePaper,2016,"Alvarado, Michelle; Lawley, Mark; Yan Li","Healthcare simulation tutorial: Methods, challenges, and opportunities",2016 Winter Simulation Conference (WSC),978-1-5090-4486-3,,10.1109/WSC.2016.7822092,http://ieeexplore.ieee.org/document/7822092/,"Simulation in healthcare is becoming an increasingly important methodology for systems improvement projects. For any given project, the simulation methodology to be used is highly application-dependent. The majority of healthcare simulation models are performed with one of three methodologies: discrete-event simulation, system dynamics, or agent-based modeling. In this tutorial we will present examples of real-world projects applied using each method. These examples, some taken from our own research, will range from complex disease progression and social determinants of health to problems in resource planning, scheduling, and allocation. We will also discuss simulation challenges unique to healthcare such as privacy and security; regulation; IRB approval; data quality, availability, and collection; interdisciplinary collaboration and facility access. Finally, we will present our thoughts on emerging opportunities for healthcare simulation such as perioperative care; coordination across the care continuum; population health management; patient health belief and behavior; and emerging healthcare regulation and policy.",2016-12,13/11/2018 10:47,14/04/2020 08:34,13/11/2018 10:07,236-247,,,,,,Healthcare simulation tutorial,,,,,IEEE,"Washington, DC, USA",,,,,,Crossref,,,,,,1; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 Winter Simulation Conference (WSC),,,,,,,,,,,,,,, 9V26HTQB,conferencePaper,2012,"Djanatliev, Anatoli; German, Reinhard; Kolominsky-Rabas, Peter; Hofmann, Bernd M.",Hybrid simulation with loosely coupled system dynamics and agent-based models for Prospective Health Technology Assessments,Proceedings Title: Proceedings of the 2012 Winter Simulation Conference (WSC),978-1-4673-4782-2 978-1-4673-4779-2 978-1-4673-4780-8 978-1-4673-4781-5,,10.1109/WSC.2012.6465024,http://ieeexplore.ieee.org/document/6465024/,"Due to the ageing of the world population, the demand for technology innovations in healthcare is growing rapidly. All stakeholders (e.g., patients, healthcare providers and health industry) can take profit of innovative products, but the development degenerates often into a time consuming and cost-intensive process. Prospective Health Technology Assessment (ProHTA) is a new approach that combines the knowledge of an interdisciplinary team and uses simulation techniques to indicate the effects of new innovations early before the expensive and risky development phase begins. In this paper, we describe an approach with loosely coupled system dynamics and agent-based models within a hybrid simulation environment for ProHTA as well as a use-case scenario with an innovative stroke technology. The project ProHTA is a part of the Centre of Excellence for Medical Technology and is supported by the German Federal Ministry of Education and Research (BMBF), project grant No. 01EX1013B.",2012-12,13/11/2018 10:47,14/04/2020 08:34,13/11/2018 10:07,01-Dec,,,,,,,,,,,IEEE,"Berlin, Germany",,,,,,Crossref,,,,,,System dynamics; 1; agent based; 320,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 Winter Simulation Conference - (WSC 2012),,,,,,,,,,,,,,, 5JHUBA5A,conferencePaper,2007,"Gibson, Ian W.; Lease, Bovis Lend",An approach to hospital planning and design using discrete event simulation,2007 Winter Simulation Conference,978-1-4244-1305-8 978-1-4244-1306-5,,10.1109/WSC.2007.4419763,http://ieeexplore.ieee.org/document/4419763/,"Recent reports have established the need for change in the US health system. Building projects can play an important role in enabling change to support organizational objectives. The current major investment in hospital construction in the US provides an opportunity to improve health service. Planning and design of hospitals generally uses benchmarks and experience without rigorous analysis of processes, resources and facility requirements. This paper considers an improved approach to planning and design of hospitals by using Discrete Event Simulation (DES) to enable improvement in the quality and productivity of health services and an improved workplace environment for staff.",2007-12,13/11/2018 10:47,14/04/2020 08:34,13/11/2018 10:07,1501-1509,,,,,,,,,,,IEEE,"Washington, DC, USA",,,,,,Crossref,,,,,,Discrete event simulation; 1; X,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2007 Winter Simulation Conference,,,,,,,,,,,,,,, TZ9BJPSU,conferencePaper,2010,"Worth, Travis; Uzsoy, Reha; Samoff, Erika; Meyer, Anne-Marie; Maillard, Jean-Marie; Wendelboe, Aaron M.",Modelling the response of a public health department to infectious disease,Proceedings of the 2010 Winter Simulation Conference,978-1-4244-9866-6,,10.1109/WSC.2010.5678917,http://ieeexplore.ieee.org/document/5678917/,"We present a discrete-event simulation model of the response of a local public health department (LHD) to pertussis cases. We take a comprehensive view of public health actions, beginning with detection of an individual patient, confirmation of the case by physician and lab tests, and contact tracing and isolation of contacts by LHD personnel. We explicitly model the information transfer between providers, laboratories and LHDs, and examine the effect of different alerting strategies on the number of confirmed cases encountered. The effect of limited resource availability for contact tracing is also examined. Given our results, we suggest that resource availability has significant impact on the progression of a disease outbreak, as do information delays at various stages of the process.",2010-12,13/11/2018 10:47,14/04/2020 08:34,13/11/2018 10:08,2185-2198,,,,,,,,,,,IEEE,"Baltimore, MD, USA",,,,,,Crossref,,,,,,1; Discrete event; 320,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2010 Winter Simulation Conference - (WSC 2010),,,,,,,,,,,,,,, 9GPLQWDZ,conferencePaper,2015,"Eatock, Julie; Lord, Joanne; Trapero-Bertran, Marta; Anagnostou, Anastasia",Discrete event simulation of whole care pathways to estimate cost-effectiveness in Clinical Guidelines,2015 Winter Simulation Conference (WSC),978-1-4673-9743-8,,10.1109/WSC.2015.7408267,http://ieeexplore.ieee.org/document/7408267/,"For pragmatic reasons, cost-effectiveness analyses performed for NICE Clinical Guidelines use a piecemeal approach, evaluating only selected aspects of diagnosis, treatment or care. A Whole Pathway approach, considering diagnosis-to-death, may provide more realistic estimates of costs and health outcomes, taking account of the healthcare context and individual risk factors, history and choices for patients with long-term conditions. A patient-level DES model using the characteristics of 12,766 real patients was created to reflect the NICE guideline for Atrial Fibrillation. Of eight topics suggested for inclusion in an update of the guideline, the model was capable of fully answering four topics, and partially answering two topics. The remaining topics were beyond the scope of the model. The model was used by NICE in their recent update of the Atrial Fibrillation Clinical Guidelines.",2015-12,13/11/2018 10:47,14/04/2020 08:34,13/11/2018 10:08,1447-1458,,,,,,,,,,,IEEE,"Huntington Beach, CA, USA",,,,,,Crossref,,,,,,1; Discrete event; 320,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 Winter Simulation Conference (WSC),,,,,,,,,,,,,,, DQC82TBN,conferencePaper,2012,"Okhmatovskaia, Anya; Buckeridge, David L.; Shaban-Nejad, Arash; Sutcliffe, Andrew; Kopec, Jacek A.; Fines, Philippe; Wolfson, Michael C.",SimPHO: An ontology for simulation modeling of population health,Proceedings Title: Proceedings of the 2012 Winter Simulation Conference (WSC),978-1-4673-4782-2 978-1-4673-4779-2 978-1-4673-4780-8 978-1-4673-4781-5,,10.1109/WSC.2012.6465128,http://ieeexplore.ieee.org/document/6465128/,"Simulation modeling of population health is being used increasingly for epidemiology research and public health policy-making. However, the impact of population health simulation models is inhibited by their complexity and the lack of established standards to describe these models. To address this issue, we are developing the Ontology for Simulation Modeling of Population Health (SimPHO) - a formal, explicit, computer-readable approach to describing population health simulation models. SimPHO builds on previous work to classify and formally represent knowledge about simulation models, and incorporates the semantics of the epidemiology and public health domains. SimPHO will allow model developers to make explicit their assumptions, to describe their models in a formal, consistent and interoperable manner, and to facilitate model reuse and integration. To illustrate the use of SimPHO, we describe one software application driven by this ontology, an automated visualization tool for generating interactive web-based diagrams of population health simulation models.",2012-12,13/11/2018 10:47,14/04/2020 08:35,13/11/2018 10:08,01-Dec,,,,,,SimPHO,,,,,IEEE,"Berlin, Germany",,,,,,Crossref,,,"

Winter Simulation Conference (WSC), Berlin, GERMANY, DEC 09-12, 2012

",,,1; ******To read; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 Winter Simulation Conference - (WSC 2012),,,,,,,,,,,,,,, 9DSFZRD9,conferencePaper,2011,"Roberts, Stephen D.",Tutorial on the simulation of healthcare systems,Proceedings of the 2011 Winter Simulation Conference (WSC),978-1-4577-2109-0 978-1-4577-2108-3 978-1-4577-2106-9 978-1-4577-2107-6,,10.1109/WSC.2011.6147860,http://ieeexplore.ieee.org/document/6147860/,"For a variety of reasons, simulation has enjoyed widespread application in health care and health care delivery systems. Although the dominant modeling methodology is discrete event simulation, numerous studies employ system dynamics, agent-based simulation, and hybrid/combined methods. Software has been increasingly adapted to health care through enhanced visualizations and modeling. Virtually every health care environment has been studied using simulation including hospitals, extended care, rehabilitation, specialty care, long-term care, public health, among others. Frequent problems are patient flow, staffing, works schedules, facilities capacity and design, admissions/scheduling, appointments, logistics, and planning. Health care problems are especially complicated by the fact that “people serve people,” meaning people are both the customer and the supply. The customers arrive through a complex decision process that produces uncertain demand. The response is an even more complex organization of health care resources, each of which play a distinctive and overlapping role, providing a unique simulation challenge.",2011-12,13/11/2018 10:47,14/04/2020 08:35,13/11/2018 10:08,1403-1414,,,,,,,,,,,IEEE,"Phoenix, AZ, USA",,,,,,Crossref,,,,,,1; ******To read; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2011 Winter Simulation Conference - (WSC 2011),,,,,,,,,,,,,,, RG4EGQW5,conferencePaper,2015,"Augusto, Vincent; Rejeb, Olfa; Xie, Xiaolan; Aloui, Saber; Perrier, Lionel; Biron, Pierre; Durand, Thierry",Performance evaluation of Health Information Systems using ARIS modeling and discrete-event simulation,2015 Winter Simulation Conference (WSC),978-1-4673-9743-8,,10.1109/WSC.2015.7408272,http://ieeexplore.ieee.org/document/7408272/,"Innovation and health-care funding reforms have contributed to the deployment of Information and Communication Technology (ICT) to improve patient care. Many health-care organizations considered the application of ICT as a crucial key to enhance health-care management. This paper aims at providing a global methodology to assess the organizational impact of high-level Health Information System (HIS) on patient pathway. We propose a performance evaluation for HIS using formal modeling with ARIS (Architecture of Integrated Information Systems) models and a Discrete Event Simulation approach. The methodology is applied to the consultation for cancer treatment process. Simulation scenarios are established to conclude about the impact of HIS on patient pathway. We demonstrated that although high level HIS lengthen the consultation, occupation rates of oncologists are lower and quality of care is higher (through number of available information accessed during the consultation). The methodology is flexible enough to be applied to other health-care systems.",2015-12,13/11/2018 10:47,14/04/2020 08:34,13/11/2018 10:08,1503-1514,,,,,,,,,,,IEEE,"Huntington Beach, CA, USA",,,,,,Crossref,,,,,,1; Discrete event; 320,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 Winter Simulation Conference (WSC),,,,,,,,,,,,,,, V5FCZ5DE,conferencePaper,2007,"Bosire, Joshua; Wang, Shengyong; Gandhi, Tejas; Srihari, Krishnaswami",Comparing simulation alternatives based on quality expectations,2007 Winter Simulation Conference,978-1-4244-1305-8 978-1-4244-1306-5,,10.1109/WSC.2007.4419776,http://ieeexplore.ieee.org/document/4419776/,"Computed Tomography (CT) is one of the fastest growing diagnostic imaging procedures. Rapid advances in imaging technologies in conjunction with their widening adoption are some of the issues that are compelling healthcare providers to restructure their systems as they seek to offer a higher quality of care to a growing volume of patients. This paper presents the application of simulation to facilitate the planning of a new CT facility for a hospital. The objective of the study was to evaluate how patient experience would be impacted by proposed design options. Waits for service were utilized as a parameter to quantify the patients' quality expectations, and hence the satisfaction derived from the healthcare services received. This study was also intended to clarify whether an additional CT-scan unit was a necessity to improving the patients' experience.",2007-12,13/11/2018 10:47,14/04/2020 08:34,13/11/2018 10:08,1579-1585,,,,,,,,,,,IEEE,"Washington, DC, USA",,,,,,Crossref,,,,,,Discrete event simulation; 1; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2007 Winter Simulation Conference,,,,,,,,,,,,,,, J6PA4WCD,conferencePaper,2015,"Williams, Roy; Williams, Scott; Das, Amar",Using agent-based simulation to understand populatation dynamics and coevolution in host-pathogen relationships,2015 Winter Simulation Conference (WSC),978-1-4673-9743-8,,10.1109/WSC.2015.7408424,http://ieeexplore.ieee.org/document/7408424/,"The development of anti-biotic resistant strains of bacteria and the nearly annual emergence of new strains of influenza virus are evidence of the rapid adaptation of pathogens to environmental pressures. The ability to predict the outcome of a long-term host-pathogen interaction could significantly improve public health decisions. Starting from the premise that all interactions between hosts and pathogens are stochastic in nature, we developed a generic agent based simulation of a population of hosts infected by a population of pathogens. Our simulation suggests that a host population is not intrinsically stable absent negative feedback loop mechanisms. We show that even in the face of a specific pathogen pressure, the outcome of a given initial host-pathogen community can be expressed only as a set of probabilities, unlike the prediction of traditional mathematical models constructed in the language of differential calculus.",2015-12,13/11/2018 10:47,14/04/2020 08:35,13/11/2018 10:09,3110-3111,,,,,,,,,,,IEEE,"Huntington Beach, CA, USA",,,,,,Crossref,,,,,,1; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 Winter Simulation Conference (WSC),,,,,,,,,,,,,,, E5S6GT2G,conferencePaper,2017,"Batata, Oussama; Augusto, Vincent; Ebrahimi, Setareh; Xie, Xiaolan",Performance evaluation of respite care services through multi-agent based simulation,2017 Winter Simulation Conference (WSC),978-1-5386-3428-8,,10.1109/WSC.2017.8248013,http://ieeexplore.ieee.org/document/8248013/,"Caregivers of patients with chronic diseases are undergoing a daily burnout in their lives. Although respite care seems a promising solution, no quantitative analysis has yet been provided to demonstrate its positive impact. In this article, we propose (i) a new model of caregivers' burnout evolution based on Markov chain and machine learning to model health state evolution, and (ii) a multi-agent based simulation approach to describe the burnout evolution of caregivers and the impact of respite structures on the system. Optimal capacity of respite structures is obtained through a design of experiment. Several management strategies are also tested (collaboration between structures, reservation of beds for emergent cases). Key performance indicators considered are quality of service and costs. Results show a positive impact of respite services on both quality of service and costs. The model also show a trade-off between quality of service and costs when bed reservation policies are used.",2017-12,13/11/2018 10:47,14/04/2020 08:34,13/11/2018 10:09,2904-2916,,,,,,,,,,,IEEE,"Las Vegas, NV",,,,,,Crossref,,,,,,1; Discrete event; 420,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 Winter Simulation Conference (WSC),,,,,,,,,,,,,,, H3TQLRI8,conferencePaper,2015,"van Buuren, Martin; Kommer, Geert Jan; van der Mei, Rob; Bhulai, Sandjai",A simulation model for emergency medical services call centers,2015 Winter Simulation Conference (WSC),978-1-4673-9743-8,,10.1109/WSC.2015.7408221,http://ieeexplore.ieee.org/document/7408221/,"In pre-hospital health care the call center plays an important role in the coordination of emergency medical services (EMS). An EMS call center handles inbound requests for EMS and dispatches an ambulance if necessary. The time needed for triage and dispatch is part of the total response time to the request, which, in turn, is an indicator for the quality of EMS. Calls entering an efficient EMS call center must have short waiting times, centralists should perform the triage efficiently and the dispatch of ambulances must be adequate and swift. This paper presents a detailed discrete event simulation model for EMS call centers. The model provides insight into the EMS call center processes and can be used to address strategic issues, such as capacity and workforce planning. We analyse results of the model that are based on real EMS call center data to illustrate the usefulness of the model.",2015-12,13/11/2018 10:47,14/04/2020 08:34,13/11/2018 10:09,844-855,,,,,,,,,,,IEEE,"Huntington Beach, CA, USA",,,,,,Crossref,,,,,,discrete event simulation; 1; 420,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 Winter Simulation Conference (WSC),,,,,,,,,,,,,,, 8UI8Y7AD,conferencePaper,2017,"Sun, Xuxue; Li, Mingyang; Meng, Chao; Kong, Nan; Meng, Hongdao; Hyer, Kathryn",Data-driven simulation for healthcare facility utilization modeling and evaluation,2017 Winter Simulation Conference (WSC),978-1-5386-3428-8,,10.1109/WSC.2017.8248010,http://ieeexplore.ieee.org/document/8248010/,"Utilization evaluation for healthcare facilities such as hospitals and nursing homes is crucial for providing high quality healthcare services in various communities. In this paper, a data-driven simulation framework integrating statistical modeling and agent-based simulation (ABS) is proposed to evaluate the utilization of various healthcare facilities. A Bayesian modeling approach is proposed to model the relationship between heterogeneous individuals' characteristics and time to readmission in the hospital and nursing home. An ABS model is developed to model the dynamically changing health conditions of individuals and readmission/discharge events. The individuals are modeled as agents in the ABS model, and their time to readmission and length of stay are driven by the developed Bayesian individualized models. An application based on Florida's Medicare and Medicaid claims data demonstrates that the proposed framework can effectively evaluate the healthcare facility utilization under various scenarios.",2017-12,13/11/2018 10:47,14/04/2020 08:34,13/11/2018 10:10,2869-2880,,,,,,,,,,,IEEE,"Las Vegas, NV",,,,,,Crossref,,,,,,1; Agent Based; 210,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 Winter Simulation Conference (WSC),,,,,,,,,,,,,,, G3GVTKSI,conferencePaper,2012,"Bigus, Joseph P.; Chen-Ritzo, Ching-Hua; Hermiz, Keith; Tesauro, Gerald; Sorrentino, Robert",Applying a framework for healthcare incentives simulation,Proceedings Title: Proceedings of the 2012 Winter Simulation Conference (WSC),978-1-4673-4782-2 978-1-4673-4779-2 978-1-4673-4780-8 978-1-4673-4781-5,,10.1109/WSC.2012.6465148,http://ieeexplore.ieee.org/document/6465148/,"At WinterSim 2011, we originally proposed an agent-based framework for healthcare simulations, enabling flexible integration of multiple simulation models, including models of disease progression, effects of provider interventions, and provider behavior models that are responsive to contractual incentives. In this paper, we report results using our proposed framework to integrate two examples of provider behavior models, two examples of disease models, and four examples of payment models. We explore multiple combinations of these models and simulate the impact that alternative payment models may have on health and financial outcomes. These examples test the robustness of the simulation framework, and illustrate the value of such simulations to the policy makers who design incentives to improve cost and health outcomes, and to providers who wish to evaluate the financial impact of proposed incentives on their practice.",2012-12,13/11/2018 10:47,14/04/2020 08:34,13/11/2018 10:10,01-Dec,,,,,,,,,,,IEEE,"Berlin, Germany",,,,,,Crossref,,,,,,1; 220; Link to community resources,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 Winter Simulation Conference - (WSC 2012),,,,,,,,,,,,,,, DZQUQQV9,conferencePaper,2014,"Gao, Amy; Osgood, Nathaniel D.; An, Wenyi; Dyck, Roland F.",A tripartite hybrid model architecture for investigating health and cost impacts and intervention tradeoffs for diabetic end-stage renal disease,Proceedings of the Winter Simulation Conference 2014,978-1-4799-7486-3 978-1-4799-7484-9,,10.1109/WSC.2014.7020018,http://ieeexplore.ieee.org/document/7020018/,"Like most countries, Canada faces rising rates of diabetes and diabetic ESRD, which adversely affect cost, morbidity/mortality and quality of life. These trends raise great challenges for financial, human resource and facility planning and place a premium on understanding tradeoffs between different intervention strategies. We describe here our hybrid simulation model built to inform such efforts. To secure computational economies while supporting upstream intervention investigation, we use System Dynamics to characterize evolution of the health, body weight and (pre-diabetes) diagnosis status of non-diabetics. Upon developing diabetes, population members are individuated into agents, thereby supporting key functionality, including accumulation of longitudinal statistics, and investigation of differential treatment regimens based on patient history. Finally, discrete event modeling is used to characterize patient progression through health care processes, so as to capture impact of resource availability, enforce queuing discipline, etc. The paper discusses model findings and tradeoffs associated with the architecture.",2014-12,13/11/2018 10:47,14/04/2020 08:34,13/11/2018 10:11,1676-1687,,,,,,,,,,,IEEE,"Savanah, GA, USA",,,,,,Crossref,,,,,,hybrid simulation; 1; 320,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2014 Winter Simulation Conference - (WSC 2014),,,,,,,,,,,,,,, PELXTDZG,conferencePaper,2013,"Ramirez-Nafarrate, Adrian; Gutierrez-Garcia, J. Octavio",An agent-based simulation framework to analyze the prevalence of child obesity,2013 Winter Simulations Conference (WSC),978-1-4799-3950-3 978-1-4799-2077-8,,10.1109/WSC.2013.6721608,http://ieeexplore.ieee.org/document/6721608/,"Child obesity is a public health problem that is of concern of several countries around the world. Long-term effects of child obesity include prevalence of chronic diseases, such as diabetes and heart-related illnesses. This paper presents an agent-based simulation framework to analyze the evolution of obesity in school-age children. In particular, in this paper we evaluate the impact of physical activity on the prevalence of child obesity using an agent-based simulation model. Simulation results suggest that the fraction of overweight and obese children at the end of elementary school can be reduced by doing physical activity with moderate intensity.",2013-12,13/11/2018 10:47,14/04/2020 08:35,13/11/2018 10:11,2330-2339,,,,,,,,,,,IEEE,"Washington, DC, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2013 Winter Simulation Conference - (WSC 2013),,,,,,,,,,,,,,, 7B9U9GDC,conferencePaper,2016,"Huang, Hao; Zabinsky, Zelda B.; Li, Yuankun; Liu, Shan",Analyzing hepatitis C screening and treatment strategies using Probabilistic Branch and Bound,2016 Winter Simulation Conference (WSC),978-1-5090-4486-3,,10.1109/WSC.2016.7822251,http://ieeexplore.ieee.org/document/7822251/,"Decisions must be made regarding screening and treatment strategies under budget constraints for chronic hepatitis C birth-cohorts in the U.S. A Markov model of disease progression is able to evaluate health utility gain using quality-adjusted life years (QALYs) for each strategy. Through conducting a simulation optimization algorithm, Probabilistic Branch and Bound (PBnB), we not only provide an optimal strategy over ten years, but also perform sensitivity analysis by approximating a set of good enough strategies. Specifically, we first identify time periods with obvious dominant strategies (allocate total budget to treatment in early years) through grid search, and then we perform PBnB to identify top 10 percent strategies for two major decision periods. Approximating a set of the top 10 percent strategies with PBnB provides decision makers the ability to explore combinations of good strategies. Also, a set of strategies indicates which decision time periods strongly impact the health utility gain.",2016-12,13/11/2018 10:47,14/04/2020 08:34,13/11/2018 10:12,2076-2086,,,,,,,,,,,IEEE,"Washington, DC, USA",,,,,,Crossref,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 Winter Simulation Conference (WSC),,,,,,,,,,,,,,, 77QDW3AP,conferencePaper,2008,"Barrett, Christopher L.; Bisset, Keith R.; Eubank, Stephen G.; Xizhou Feng; Marathe, Madhav V.",EpiSimdemics: An efficient algorithm for simulating the spread of infectious disease over large realistic social networks,"2008 SC - International Conference for High Performance Computing, Networking, Storage and Analysis",978-1-4244-2834-2,,10.1109/SC.2008.5214892,http://ieeexplore.ieee.org/document/5214892/,"Preventing and controlling outbreaks of infectious diseases such as pandemic influenza is a top public health priority. We describe EpiSimdemics - a scalable parallel algorithm to simulate the spread of contagion in large, realistic social contact networks using individual-based models. EpiSimdemics is an interaction-based simulation of a certain class of stochastic reaction-diffusion processes. Straightforward simulations of such process do not scale well, limiting the use of individual-based models to very small populations. EpiSimdemics is specifically designed to scale to social networks with 100 million individuals. The scaling is obtained by exploiting the semantics of disease evolution and disease propagation in large networks. We evaluate an MPI-based parallel implementation of EpiSimdemics on a mid-sized HPC system, demonstrating that EpiSimdemics scales well. EpiSimdemics has been used in numerous sponsor defined case studies targeted at policy planning and course of action analysis, demonstrating the usefulness of EpiSimdemics in practical situations.",2008-11,13/11/2018 10:47,14/04/2020 08:34,13/11/2018 10:13,01-Dec,,,,,,EpiSimdemics,,,,,IEEE,"Austin, TX, USA",,,,,,Crossref,,,,,,parallel algorithm; 1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2008 SC - International Conference for High Performance Computing, Networking, Storage and Analysis",,,,,,,,,,,,,,, ZPZMPUDV,conferencePaper,2014,"Li, Yan; Kong, Nan; Lawley, Mark; Pagan, Jose A.",Assessing lifestyle interventions to improve cardiovascular health using an agent-based model,Proceedings of the Winter Simulation Conference 2014,978-1-4799-7486-3 978-1-4799-7484-9,,10.1109/WSC.2014.7019979,http://ieeexplore.ieee.org/document/7019979/,"Cardiovascular disease (CVD) is the leading cause of death in the United States (US) and places a heavy economic burden on the healthcare system. Recognizing the importance of CVD prevention, in recent years the American Heart Association (AHA) began to emphasize the need to increase awareness of key risk factors of CVD and proposed a new concept called ideal cardiovascular health. Based on this concept, we developed an agent-based model that is designed to capture individual health progression and study emergent CVD-related population health outcomes (diabetes, myocardial infarction, stroke and death) over a specified time period. We present some preliminary numerical results, which demonstrate the predictive validity of the model and show how the model could be used in practice by assessing the impact of a set of hypothetical lifestyle interventions on CVD-related health outcomes. Our model is designed to help policy-makers assess and compare different intervention programs targeting CVD prevention for the population of their interest.",2014-12,13/11/2018 10:47,14/04/2020 08:34,13/11/2018 10:13,1221-1232,,,,,,,,,,,IEEE,"Savanah, GA, USA",,,,,,Crossref,,,,,,1; Agent-based model; 410,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2014 Winter Simulation Conference - (WSC 2014),,,,,,,,,,,,,,, 5C6TM5E2,conferencePaper,2014,"Wang, Fei; Srinivasan, Uma; Uddin, Shahadat; Chawla, Sanjay",Application of network analysis on healthcare,2014 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining (ASONAM 2014),978-1-4799-5877-1,,10.1109/ASONAM.2014.6921647,http://ieeexplore.ieee.org/document/6921647/,"The healthcare sector holds large amounts of semantically rich electronic data generated and used by different sections of the health care community. Data analytic techniques such as data mining and predictive modelling are being used to gain new insights into health care costs, performance and quality of care. In this context, social network analysis (SNA) has the unique ability to play a new role in exploring the context and situations that lead to efficient and effective healthcare. In this paper we describe a specific context of private healthcare in Australia and describe our SNA based approach (applied to health insurance claims) to understand the nature of collaboration among doctors treating hospital inpatients and explore the impact of collaboration on cost and quality of care. In particular, we use network analysis to (a) design collaboration models among surgeons, anaesthetists and assistants who work together while treating patients admitted for specific types of treatments (b) identify and extract specific types of network topologies that indicate the way doctors collaborate while treating patients and (c) analyse the impact of these topologies on cost and quality of care provided to those patients.",2014-08,13/11/2018 10:47,14/04/2020 08:35,13/11/2018 10:13,596-603,,,,,,,,,,,IEEE,China,,,,,,Crossref,,,,,,social network; health care; 1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2014 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining (ASONAM),,,,,,,,,,,,,,, 9JM94S7R,conferencePaper,2011,"Beeler, Michael F.; Aleman, Dionne M.; Carter, Michael W.",Estimation and management of pandemic influenza transmission risk at mass immunization clinics,Proceedings of the 2011 Winter Simulation Conference (WSC),978-1-4577-2109-0 978-1-4577-2108-3 978-1-4577-2106-9 978-1-4577-2107-6,,10.1109/WSC.2011.6147834,http://ieeexplore.ieee.org/document/6147834/,"Mass immunization clinics (MICs) have become an essential component of pandemic influenza response strategies. By deploying large volumes of vaccines at centralized locations, public health authorities can reduce the complexity of emergency vaccine distribution while also enabling rapid, large-scale vaccination. The risk of influenza transmission at MICs must be understood and mitigated to maximize their effectiveness. We have developed a discrete-event simulation of an MIC that can estimate the expected number of infections resulting from disease transmission within the facility. A simulation experiment is conducted that varies MIC crowdedness, staffing levels and the percentage of infectious individuals entering the MIC-symptomatic or not-to assess the impact of these factors on expected infections. It is shown that the number of expected infections occurring in the MIC, though a small fraction of the influenza cases likely averted due to vaccination, is large enough to warrant mitigation measures.",2011-12,13/11/2018 10:47,14/04/2020 08:34,13/11/2018 10:15,1117-1124,,,,,,,,,,,IEEE,"Phoenix, AZ, USA",,,,,,Crossref,,,,,,discrete event simulation; 1; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2011 Winter Simulation Conference - (WSC 2011),,,,,,,,,,,,,,, 82P2AKLZ,conferencePaper,2010,"Soorapanth, Sada; Chick, Stephen E.",Cost-utility analysis of behavioral interventions for HIV-infected persons to reduce HIV transmission in the USA,Proceedings of the 2010 Winter Simulation Conference,978-1-4244-9866-6,,10.1109/WSC.2010.5678939,http://ieeexplore.ieee.org/document/5678939/,"We developed an ordinary differential equation model to analyze the cost and utility (measured in quality adjusted life years, or QALYs) of three published behavioral HIV interventions that aim to reduce the risk of transmission from HIV-infected persons to their sexual partners. The ODE model maps measurements of behavioral risk reduction parameters, estimated from sampling, into costs and QALYs. Monte Carlo sampling was used to perform a probabilistic sensitivity analysis to quantify uncertainty in costs and QALYs due to parameter estimation error from sampling. The results suggested that the behavioral interventions considered in this study are most likely to be cost-saving, or at least cost-effective. Our study shows how statistical estimates of behavioral measures translates into uncertainty about health costs and outcomes and suggests implications for which data are important to collect when assessing cost-utility tradeoffs, and not just measures of risk reduction from behavioral interventions.",2010-12,13/11/2018 10:47,14/04/2020 08:35,13/11/2018 10:15,2433-2443,,,,,,,,,,,IEEE,"Baltimore, MD, USA",,,,,,Crossref,,,,,,1; ODE; Ordinary Differential Equation model; Monte Carlo; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2010 Winter Simulation Conference - (WSC 2010),,,,,,,,,,,,,,, KWI4DMLA,conferencePaper,2010,"Rohleder, Thomas; Huschka, Todd; Egginton, Jason; O'Neil, Dan; Woychick, Naomi",Modeling care teams at Mayo Clinic,Proceedings of the 2010 Winter Simulation Conference,978-1-4244-9866-6,,10.1109/WSC.2010.5678928,http://ieeexplore.ieee.org/document/5678928/,"At Mayo Clinic, care teams are being evaluated as a means to improve health care staff productivity and patient service. Traditional care in outpatient practices has health care staff working independently of each other with little coordination. Initial feedback by participating practices support the value of care teams. Our research focuses on a quantitative analysis of the care teams approach. By collecting detailed task data related to patient visits we then use discrete-event simulation to design alternative care team configurations, analyze staffing cost options, and compare these to traditional outpatient care delivery.",2010-12,13/11/2018 10:47,14/04/2020 08:34,13/11/2018 10:15,2304-2314,,,,,,,,,,,IEEE,"Baltimore, MD, USA",,,,,,Crossref,,,,,,discrete event simulation; 1; 320,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2010 Winter Simulation Conference - (WSC 2010),,,,,,,,,,,,,,, PFAQG3DK,conferencePaper,2007,"Eldabi, Tillal; Young, Terry",Towards a framework for healthcare simulation,2007 Winter Simulation Conference,978-1-4244-1305-8 978-1-4244-1306-5,,10.1109/WSC.2007.4419756,http://ieeexplore.ieee.org/document/4419756/,"The changing needs of healthcare provision around the world are forcing service designers and decision makers to adopt new tools in design and evaluation of processes. Apart from the pressure to deliver better services from constrained resources, the increasing use of metrics to monitor and manage care delivery, also means that service providers require a clearer idea of how a service improvement will perform prior to implementation. In turn, this opens up an opportunity for a much greater use of simulation and modeling techniques, provided they can be set within an appropriate framework. This paper discusses and describes a research project aimed at conducting pilot work for developing a framework that facilitates joined up thinking and enables integrative modeling. An approach to achieving such an end is described and progress to date is reported. Since this is an ongoing project, some of the latest results are presented at the conference.",2007-12,13/11/2018 10:47,14/04/2020 08:34,13/11/2018 10:16,1454-1460,,,,,,,,,,,IEEE,"Washington, DC, USA",,,,,,Crossref,,,,,,1; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2007 Winter Simulation Conference,,,,,,,,,,,,,,, 43754SPG,conferencePaper,2008,"Yurtkuran, Alkin; Emel, Erdal",Simulation based decision-making for hospital pharmacy management,2008 Winter Simulation Conference,978-1-4244-2707-9,,10.1109/WSC.2008.4736235,http://ieeexplore.ieee.org/document/4736235/,"Managing healthcare delivery systems plays an important role for healthcare providers in order to have high quality service performances. Inpatient pharmacy delivery systems are one of those that have a key role in hospital¿s service quality. Simulation is the best tool to analyze the hospital pharmacy operations due to their inherent complexity. In this article, a simulation model is developed based on data collected from a hospital in Turkey to analyze its pharmacy delivery system. In comparison to the baseline system, two different scenarios with varying factors are investigated, seeking to minimize drug delivery time to patients. The results presented here indicate the possibility for improved system performance.",2008-12,13/11/2018 10:47,14/04/2020 08:34,13/11/2018 10:16,1539-1546,,,,,,,,,,,IEEE,"Miami, FL, USA",,,,,,Crossref,,,,,,1; Discrete event; 320,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2008 Winter Simulation Conference (WSC),,,,,,,,,,,,,,, 9YBYX4D3,conferencePaper,2017,"Reinhardt, Lorenz; Monch, Lars",Simulation-based optimiziation to design equipment health-aware dispatching rules,2017 Winter Simulation Conference (WSC),978-1-5386-3428-8,,10.1109/WSC.2017.8248070,http://ieeexplore.ieee.org/document/8248070/,"In this paper, we discuss the construction of dispatching rules for semiconductor wafer fabrication facilities (wafer fabs) that take equipment health issues into account. Monitoring the equipment health status of critical machines is important to maintain process quality and to reduce rework and scrap. Usually, there is a tradeoff between quality- and productivity-related goals in wafer fabs. Obtaining an appropriate compromise between these two objectives is addressed by considering blended dispatching rules. Simulation-based optimization based on variable neighborhood search (VNS) using a reduced simulation model of a wafer fab is applied to determine appropriate weights for the different priority indices. We demonstrate by simulation experiments that the obtained blended dispatching rule performs well compared to dispatching rules that are designed only for a single quality- or productivity-related objective.",2017-12,13/11/2018 10:47,14/04/2020 08:35,13/11/2018 10:16,3565-3575,,,,,,,,,,,IEEE,"Las Vegas, NV",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 Winter Simulation Conference (WSC),,,,,,,,,,,,,,, K6BT8WWT,conferencePaper,2009,"Thorwarth, Michael; Arisha, Amr; Harper, Paul",Simulation model to investigate flexible workload management for healthcare and servicescape environment,Proceedings of the 2009 Winter Simulation Conference (WSC),978-1-4244-5770-0,,10.1109/WSC.2009.5429210,http://ieeexplore.ieee.org/document/5429210/,"High demand and poor staffing conditions cause avoidable pressure and stress among healthcare personnel which results in burnout symptoms and unplanned absenteeism which are hidden cost drivers. The work environment within an emergency department is commonly arranged in a flexible workload which is highly dynamic and complex for the outside observer. Using detailed simulation modeling within structured modeling methods, a comprehensive model to characterize the nurses' time utilization in such flexible dynamic workload environment was investigated. The results have been used to derive a generalized analytic expression that describes certain settings that lead to an instable queuing system with serious consequences for the healthcare facility. Thus decision makers are hence equipped with a tool which allows identifying and preventing such conditions that affect service quality level.",2009-12,13/11/2018 10:47,14/04/2020 08:35,13/11/2018 10:16,1946-1956,,,,,,,,,,,IEEE,"Austin, TX, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2009 Winter Simulation Conference - (WSC 2009),,,,,,,,,,,,,,, ELE7HGNC,conferencePaper,2011,"Ferranti, Jocimara S.; de Freitas Filho, Paulo J.",Dynamic mortality simulation model incorporating risk indicators for cardiovascular diseases,Proceedings of the 2011 Winter Simulation Conference (WSC),978-1-4577-2109-0 978-1-4577-2108-3 978-1-4577-2106-9 978-1-4577-2107-6,,10.1109/WSC.2011.6147847,http://ieeexplore.ieee.org/document/6147847/,"This article describes a dynamic-fuzzy simulation model and proposes an extension to it. The model represents a person's physiological capacity throughout life and simulates the occurrence of risk events from birth until death, including a representation of the process of recovering health after it has been impacted by a risk event. The expanded model incorporates cardiovascular risk factors in order to reproduce curves plotted from real mortality data from a specific population whose cause of death was cardiovascular diseases. By adjusting the parameters, it proved possible to reproduce mortality curves from populations with specific characteristics such as hypertension, obesity and physical activity levels. A simulation model that is capable of focusing on specific populations makes it possible to test alternative intervention designed to reduce the mortality caused by specific diseases, thereby contributing to improved quality-of-life for populations and to cost savings for both public and private health care systems.",2011-12,13/11/2018 10:47,14/04/2020 08:34,13/11/2018 10:19,1263-1274,,,,,,,,,,,IEEE,"Phoenix, AZ, USA",,,,,,Crossref,,,,,,System dynamics; 1; 320,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2011 Winter Simulation Conference - (WSC 2011),,,,,,,,,,,,,,, 7FP72YFS,conferencePaper,2008,"Tsai, Yu-Shiuan; Sun, Chuen-Tsai; Huang, Chung-Yuan",Epidemic Dynamics and Thresholds in Agent-Based Simulations under Realistic Resources and Cost Conditions,2008 IEEE/WIC/ACM International Conference on Web Intelligence and Intelligent Agent Technology,978-0-7695-3496-1,,10.1109/WIIAT.2008.11,http://ieeexplore.ieee.org/document/4740597/,"Critical threshold is one of the most important epidemiological indicators of whether or not an epidemic outbreak has occurred. Recent studies have been overly focused on ways that the power-law connectivity distribution features of social networks affect epidemic dynamics and spreading situations. Two important factors have been overlooked as a result: resource limitations and transmission costs associated with face-to-face interactions and daily contact. Our two main findings are: (a) a significant critical threshold does exist when resources and costs are taken into consideration, and that threshold has a lower bound whenever contagion events occur in scale-free social networks; and (b) the spread of epidemics in scale-free social networks remains controllable as long as resources are properly restricted and consumed costs in the form of public health strategies are significantly increased.",2008-12,13/11/2018 10:47,14/04/2020 08:34,13/11/2018 10:20,65-70,,,,,,,,,,,IEEE,"Sydney, Australia",,,,,,Crossref,,,,,,critical threshold; effective spreading rate; resources constraints; scale-free networks; transmission costs; 1; Agent Based; 420,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2008 IEEE/WIC/ACM International Conference on Web Intelligence and Intelligent Agent Technology,,,,,,,,,,,,,,, AC73MDCA,conferencePaper,2015,"Rashwan, Wael; Arisha, Amr",Modeling behavior of nurses in clinical medical unit in university hospital: Burnout implications,2015 Winter Simulation Conference (WSC),978-1-4673-9743-8,,10.1109/WSC.2015.7408544,http://ieeexplore.ieee.org/document/7408544/,"High demand of healthcare services due to changes in population demography, technological and medical advancements, budget limitations have direct effect on medical staff and medical organizations in particularly hospitals. One of the major issues confronting the healthcare system is staff behavior when they get close to `burnout' level. This study identifies factors affecting nurses' behavior and its impact on patients experience time using system dynamics. A particular focus is given to nurses in one of the medical clinical units in one of the largest hospitals in Ireland. Armed with a comprehensive system dynamic model that revolves around the staff stresses, an examination of Skill-Mix, Work Intensity, and Time Per Activity is conducted to examine performance issues due to nurses' fatigue and burnout. Results demonstrate serious consequences on patients' experience time and service quality measures as a proportional result of the increased pressures on nurses in this unit.",2015-12,13/11/2018 10:47,14/04/2020 08:34,13/11/2018 10:21,3880-3891,,,,,,Modeling behavior of nurses in clinical medical unit in university hospital,,,,,IEEE,"Huntington Beach, CA, USA",,,,,,Crossref,,,,,,System dynamics; 1; 420,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 Winter Simulation Conference (WSC),,,,,,,,,,,,,,, S64N5QBE,conferencePaper,2009,"Wang, Hui; Xiong, Wei; Hupert, Nathaniel; Sandrock, Christian; Siddiqui, Javeed; Bair, Aaron",Concept of operations for a regional telemedicine hub to improve medical emergency response,Proceedings of the 2009 Winter Simulation Conference (WSC),978-1-4244-5770-0,,10.1109/WSC.2009.5429247,http://ieeexplore.ieee.org/document/5429247/,"Telemedicine (TM) is a tool that permits medical services to be provided remotely. Applications of telemedicine to disaster response began in the mid-1980s for natural disasters such as earthquakes, tsunamis, and hurricanes and for ¿staged¿ disasters in experiments and exercises. These activities led to the concept of a regional telemedicine hub (TMH) with an extended network of clinical providers, which potentially could alleviate problems associated with surge capacity during disaster response. However, health-related benefits associated with this organizational model for disaster-related telemedicine remain to be quantitatively tested. In this paper, we describe a simulation study used to examine the operation of a regional telemedicine hub during the acute phases of hospital patient management in a hypothetical earthquake scenario. We explore the impact of using telemedicine to provide emergency specialty care to expand surge capacities at both local and regional levels.",2009-12,13/11/2018 10:47,14/04/2020 08:35,13/11/2018 10:21,2809-2819,,,,,,,,,,,IEEE,"Austin, TX, USA",,,,,,Crossref,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2009 Winter Simulation Conference - (WSC 2009),,,,,,,,,,,,,,, L3T6QKBQ,conferencePaper,2016,"Ho, Ting-Yu; Fishman, Paul A.; Zabinsky, Zelda B.",Designing and analyzing healthcare insurance policies to reduce cost and prevent the spread of seasonal influenza,2016 Winter Simulation Conference (WSC),978-1-5090-4486-3,,10.1109/WSC.2016.7822246,http://ieeexplore.ieee.org/document/7822246/,"Getting seasonal flu vaccines and seeking medical treatments are two effective strategies to prevent the spread of seasonal influenza. However, less than half of Americans received flu vaccines in the 2014-2015 flu season. A high cost-sharing rate in healthcare insurance policies results in few patients to visit doctors, leading to slow recovery rate. In this paper, we design insurance policies, including vaccination incentives and cost-sharing, to encourage the insurants to receive a flu vaccine and prevent the spread of seasonal influenza. Dynamic interaction between a single insurer and multiple insurants is formulated as a Stackelberg vaccination game and agent-based modeling is implemented to simulate the spread of flu in a population under different insurance policies. Simulation and experimental results indicate that the proposed mechanism can effectively improve vaccination behavior and maintain low infection rates even with a highly contagious flu.",2016-12,13/11/2018 10:47,14/04/2020 08:34,13/11/2018 10:22,2018-2029,,,,,,,,,,,IEEE,"Washington, DC, USA",,,,,,Crossref,,,,,,1; Agent Based; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 Winter Simulation Conference (WSC),,,,,,,,,,,,,,, YABQKT6L,conferencePaper,2015,"Liu, Zhengchun; Rexachs, Dolores; Luque, Emilio; Epelde, Francisco; Cabrera, Eduardo",Simulating the micro-level behavior of emergency department for macro-level features prediction,2015 Winter Simulation Conference (WSC),978-1-4673-9743-8,,10.1109/WSC.2015.7408162,http://ieeexplore.ieee.org/document/7408162/,"Emergency departments are currently facing major pressures due to rising demand caused by population growth, aging and high expectations of service quality. With changes continuing to challenge healthcare systems, developing solutions and formulating policies require a good understanding of the complex and dynamic nature of the relevant systems. However, as a typically complex system, it is hard to grasp the non-linear association between macro-level features and micro-level behavior for a systematic understanding. Instead of describing all the potential causes of this complex issue, in this paper we present a layer-based application framework to discover knowledge of an emergency department system through simulating micro-level behaviors of its components to facilitate a systematic understanding. Finally, case studies are used to demonstrate the potential use of the proposed approach. Results show that the proposed framework can significantly rtheeflect the non-linear association between micro-level behavior and macro-level features.",2015-12,13/11/2018 10:47,14/04/2020 08:34,13/11/2018 10:23,171-182,,,,,,,,,,,IEEE,"Huntington Beach, CA, USA",,,,,,Crossref,,,,,,1; 320,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 Winter Simulation Conference (WSC),,,,,,,,,,,,,,, IPFM8ZVI,conferencePaper,2009,"Bohk, Christina; Ewald, Roland; Uhrmacher, Adelinde M.",Probabilistic population projection with JAMES II,Proceedings of the 2009 Winter Simulation Conference (WSC),978-1-4244-5770-0,,10.1109/WSC.2009.5429715,http://ieeexplore.ieee.org/document/5429715/,"Predicting future populations and their structure is a central theme in demography. It is related to public health issues, political decision-making, or urban planning. Since these predictions are concerned with the evolution of a complex system, they exhibit a considerable uncertainty. Accounting for this inherent uncertainty is crucial for subsequent decision processes, as it reveals the range of possible outcomes and their likelihood. Consequently, probabilistic prediction approaches emerged over the past decades. This paper describes the probabilistic population projection model (PPPM), a recently developed method that allows detailed projections, but has a complex structure and requires much input data. We discuss the development of P3J, a tool that helps users in managing and executing projections and is built on top of the simulation system JAMES II. We outline how even specific tools like P3J profit from general-purpose simulation frameworks like JAMES II, and illustrate its usage by a simple example.",2009-12,13/11/2018 10:47,14/04/2020 08:34,13/11/2018 10:24,2008-2019,,,,,,,,,,,IEEE,"Austin, TX, USA",,,,,,Crossref,,,,,,1; X,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2009 Winter Simulation Conference - (WSC 2009),,,,,,,,,,,,,,, XDEPE8TK,conferencePaper,2010,"Lara, James",Keynote II,2010 IEEE Workshop on Principles of Advanced and Distributed Simulation,978-1-4244-7292-5,,10.1109/PADS.2010.5471649,http://ieeexplore.ieee.org/document/5471649/,"Molecular epidemiology of viral infections is based on identifying genetic markers to assist in epidemiological investigation. Early molecular technologies were limited in its capacity and were dominated by analytical methodology focusing on the viral agent itself where computational technologies were almost exclusively used for phylogenetic inference. Embracing the approaches and achievements of molecular epidemiology, integrative molecular epidemiology of viral infections expands into a comprehensive analysis of factors involved into defining outcomes of exposure of a person or population of people to viral infections. The major emphasis of this scientific discipline is on the development of predictive models that can be used in different clinical and public health settings. Qualitative or modestly accurate quantitative models, however, can be used for guiding research. This presentation briefly reviews a few examples that illustrate new trends in integrative molecular epidemiology approaches striving to quantitatively define viral properties and parameters using primary structure of viral genomes. The promise and importance that such approaches hold for improving predictors of infection outcome are becoming perceivable with recent advances in high-performance computation technologies and provide opportunities for computational research.",2010-05,13/11/2018 10:47,14/04/2020 08:42,13/11/2018 10:26,01-Feb,,,,,,,,,,,IEEE,"Atlanta, GA, USA",,,,,,Crossref,,,,,,public health; clinical health; genetic markers; hepatitis C virus infection; integrative molecular epidemiology; phylogenetic inference; viral agent; viral genomes; 1; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2010 IEEE 24th Workshop on Principles of Advanced and Distributed Simulation (PADS),,,,,,,,,,,,,,, 7FKA5FBK,conferencePaper,2008,"Tijerino, Yuri A.; El-Bassuny, Tarek Helmy; Bradshaw, Jeffrey M.",FAQIH: Framework for Agent-Based Query-Enabled Integrated Information for Health and Nutrition,2008 IEEE/WIC/ACM International Conference on Web Intelligence and Intelligent Agent Technology,978-0-7695-3496-1,,10.1109/WIIAT.2008.405,http://ieeexplore.ieee.org/document/4740840/,"As the processes of urbanization and globalization continue to gain momentum, issues relating to interdependencies among water, food, nutrition and public health policy have increased in complexity and scope. Thus, it is no longer sufficient for subject-matter experts to develop models for each of their underlying domains of expertise (e.g., nutrition, healthcare, and land and water management) independently. Both expert stakeholders and ordinary citizens would benefit from reliable and continually up-to-date models on which to base their decisions. In this preliminary overview paper, the authors propose to develop a Framework for Agent-based Query-Enabled Integrated Information for Health and Nutrition (FAQIH) to support healthcare professionals, policy makers, and citizens to obtain the knowledge they seek.",2008-12,13/11/2018 10:47,14/04/2020 08:35,13/11/2018 10:26,550-553,,,,,,FAQIH,,,,,IEEE,"Sydney, Australia",,,,,,Crossref,,,,,,Nutrition; Ontology; Semantic Web; 1; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2008 IEEE/WIC/ACM International Conference on Web Intelligence and Intelligent Agent Technology,,,,,,,,,,,,,,, MLF8Y4FB,conferencePaper,2016,"Fares, Julian; Chung, Kon Shing Kenneth",Personal networks and perception of care,2016 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining (ASONAM),978-1-5090-2846-7,,10.1109/ASONAM.2016.7752389,http://ieeexplore.ieee.org/document/7752389/,"During the past decade there has been a growing research interest in the effects of social support, characterized by social relationships and affiliation, on health. As health management is largely a social process, social networks have been theorized to impact health outcomes. We find however, an important gap in the literature. Little attention has been given to how the social structure and social position impact cancer care experience. The National Cancer Patient Experience survey 2010 is used to demonstrate how network data can be extracted for the purpose of studying the impact of social network properties on perception of care. The results show that there is a significant difference in network properties (density, betweenness, degree, closeness, efficiency, constraint) of patients who were treated as a whole person or as a cancer symptom. We believe that social networks can help in improving the future service quality for cancer patients.",2016-08,13/11/2018 10:47,14/04/2020 08:34,13/11/2018 10:30,1181-1188,,,,,,,,,,,IEEE,"San Francisco, CA, USA",,,,,,Crossref,,,,,,egocentric; social network; cancer care; perception of care; position; social support; structure; 1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining (ASONAM),,,,,,,,,,,,,,, 84QHFI9T,conferencePaper,2014,"Hemmati, Azadeh; Chung, Kon Shing Kenneth",Associations between personal social network properties and mental health in cancer care,2014 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining (ASONAM 2014),978-1-4799-5877-1,,10.1109/ASONAM.2014.6921682,http://ieeexplore.ieee.org/document/6921682/,"In this study, we develop a theoretical model based on social network theories and the quality of life (QOL) model to understand how social support would influence Global Mental QOL in the context of cancer patients. While extant literature showing how structural, dyadic and network level perspectives influence QOL remain lacking, this study contributes towards addressing this gap. It also illustrates how social network data, which is primarily time consuming to obtain, can be extracted from current social surveys. Using the U.S. National Health Interview Survey 2010, we (i) demonstrate how relational data is extracted for (ii) investigating the association between egocentric network properties (structure, position and relations) and Global Mental QOL. Results show that there are significant differences in the network properties (density, degree, tie strength, efficiency and constraint) of those experiencing good and poor Global Mental QOL. These findings are critical to influencing interventions and policy development for enhanced Mental QOL in cancer care.",2014-08,13/11/2018 10:47,14/04/2020 08:34,13/11/2018 10:34,828-835,,,,,,,,,,,IEEE,China,,,,,,Crossref,,,,,,cancer; social network; social support; structure; egocentric network; ties; mental QOL; 1; Social Network Analysis; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2014 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining (ASONAM),,,,,,,,,,,,,,, NGWLGW3L,journalArticle,2013,"Yu, Junhua; Shah, Bijal M.; Ip, Eric J.; Chan, James",A Markov model of the cost-effectiveness of pharmacist care for diabetes in prevention of cardiovascular diseases: evidence from Kaiser Permanente Northern California.,Journal of managed care pharmacy : JMCP,,1944-706X 1083-4087,10.18553/jmcp.2013.19.2.102,,"BACKGROUND: It has been demonstrated in previous studies that pharmacist management of patients with type 2 diabetes mellitus (T2DM) in the outpatient setting not only improves diabetes-related clinical outcomes such as hemoglobin A1c but also blood pressure (BP), total cholesterol (TC), and quality of life. Improved control of BP and TC has been shown to reduce the risks of cardiovascular disease (CVD), which has placed a heavy economic burden on the health care system. However, no study has evaluated the cost-effectiveness of pharmacist intervention programs with respect to the long-term preventive effects on CVD outcomes among T2DM patients. OBJECTIVES: To (a) quantify the long-term preventive effects of pharmacist intervention on CVD outcomes among T2DM patients using evidence from a matched cohort study in the outpatient primary care setting and (b) assess the relative cost-effectiveness of adding a clinical pharmacist to the primary care team for the management of patients with T2DM based on improvement in CVD risks with the aid of an economic model. METHODS: Clinical data between the periods of June 2007 to February 2010 were collected from electronic medical records at 2 separate clinics at Kaiser Permanente (KP) Northern California, 1 with primary care physicians only (control group) and the other with the addition of a pharmacist (enhanced care group). Patients in the enhanced care group were matched 1:1 with patients in the control group according to baseline characteristics that included age, gender, A1c, and Charlson comorbidity score. The estimated 10-year CVD risk for both groups was calculated by the United Kingdom Prospective Diabetes Study (UKPDS) Risk Engine (version 2) based on age, sex, race, smoking status, atrial fibrillation, duration of diabetes, levels of A1c, systolic BP (SBP) and TC, and high-density lipoprotein cholesterol (HDL-C) observed at 12 months. There was no statistical difference in the baseline clinical inputs to the Risk Engine (A1c [P=0.115], SBP [P=0.184], TC [P=0.055], and HDL-C [P=0.475]) between the 2 groups. A Markov model was developed to simulate the estimated CVD outcomes over 10 years and to estimate cost-effectiveness. The final outcomes examined included incremental cost and effectiveness measured by life years and per quality-adjusted life year gained. Both deterministic sensitivity analysis (SA) and probabilistic SA were conducted to examine the robustness of the results. RESULTS: The estimated risks for coronary heart disease (CHD) and stroke (both nonfatal and fatal) at the end of the follow-up were consistently lower in the enhanced care group compared with the control group, even though baseline risks in both groups were similar. The absolute risk reduction (ARR) between the enhanced care and control groups increased over time. For example, the ARR for nonfatal CHD risk in year 1 was 0.5% (1.2% vs. 0.7%), whereas the ARR increased to 5.5% in year 10 (14.8% vs. 9.3%). Similarly, the ARR between the enhanced care and the control groups was calculated as 0.3% for fatal CHD in year 1 and increased to 4.6% in year 10. Results from the Markov model suggest that the enhanced care group was shown to be a dominant strategy (less expensive and more effective) compared with the control group in the 10-year evaluation period in the base-case (average or mean results) scenario. Sensitivity analysis that took into account the uncertainty in all important variables, such as wage of pharmacists, utility weight (the degree of preference individuals have for a particular health state or condition), response rate to pharmacists' care, and uncertainty associated with the estimated 10 years of CVD risk, revealed that the relative value of enhanced care was robust to most of the variations in these parameters. Notably, the level of cost-effectiveness measured by net monetary value depends on the time horizon adopted by the payers and the magnitude of CVD risk reduction. The enhanced care group has a higher chance of being considered as a cost-effective strategy when a longer time horizon such as a minimum of 4 to 5 years is adopted. CONCLUSIONS: Adding pharmacists to the health care management team for diabetic patients improves the long-term CVD risks. The longer-term CVD risk reductions were shown to be more dramatic than the short-term reduction. A longer time horizon adopted by health plans in managing T2DM patients has a higher probability of making the intervention cost-effective.",2013-03,13/11/2018 10:47,14/04/2020 08:35,,102-114,,2,19,,J Manag Care Pharm,,,,,,,,eng,,,,,,,PMID: 23461426,,,,"Humans; Cost-Benefit Analysis; Health Care Costs; Risk Factors; *Models, Economic; Cohort Studies; Markov Chains; Retrospective Studies; Medication Adherence; California/epidemiology; Primary Health Care/*economics; Cardiovascular Diseases/economics/epidemiology/*prevention & control; Combined Modality Therapy; Diabetes Mellitus, Type 2/*drug therapy/economics/therapy; Health Maintenance Organizations/*economics; Hypoglycemic Agents/economics/*therapeutic use; Pharmaceutical Services/*economics; Pharmacology, Clinical/manpower; 1; ****; markov; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JU5JT2U9,journalArticle,2013,"Tennant, Marc; Kruger, Estie",A dental public health approach based on computational mathematics: Monte Carlo simulation of childhood dental decay.,International dental journal,,0020-6539 0020-6539,10.1111/idj.12003,,"This study developed a Monte Carlo simulation approach to examining the prevalence and incidence of dental decay using Australian children as a test environment. Monte Carlo simulation has been used for a half a century in particle physics (and elsewhere); put simply, it is the probability for various population-level outcomes seeded randomly to drive the production of individual level data. A total of five runs of the simulation model for all 275,000",2013-02,13/11/2018 10:47,14/04/2020 08:35,,39-42,,1,63,,Int Dent J,,,,,,,,eng,(c) 2013 FDI World Dental Federation.,,,,,,PMID: 23410020,,,,"Humans; Risk Factors; *Models, Statistical; Child; Monte Carlo Method; Incidence; Prevalence; Social Class; Australia/epidemiology; DMF Index; Dental Caries/*epidemiology; Oceanic Ancestry Group/statistics & numerical data; Public Health Dentistry/*methods; Sampling Studies; 1; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MACU47SV,journalArticle,2012,"Marshall, Brandon D. L.; Paczkowski, Magdalena M.; Seemann, Lars; Tempalski, Barbara; Pouget, Enrique R.; Galea, Sandro; Friedman, Samuel R.",A complex systems approach to evaluate HIV prevention in metropolitan areas: preliminary implications for combination intervention strategies.,PloS one,,1932-6203 1932-6203,10.1371/journal.pone.0044833,,"BACKGROUND: HIV transmission among injecting and non-injecting drug users (IDU, NIDU) is a significant public health problem. Continuing propagation in endemic settings and emerging regional outbreaks have indicated the need for comprehensive and coordinated HIV prevention. We describe the development of a conceptual framework and calibration of an agent-based model (ABM) to examine how combinations of interventions may reduce and potentially eliminate HIV transmission among drug-using populations. METHODOLOGY/PRINCIPAL FINDINGS: A multidisciplinary team of researchers from epidemiology, sociology, geography, and mathematics developed a conceptual framework based on prior ethnographic and epidemiologic research. An ABM was constructed and calibrated through an iterative design and verification process. In the model, ""agents"" represent IDU, NIDU, and non-drug users who interact with each other and within risk networks, engaging in sexual and, for IDUs, injection-related risk behavior over time. Agents also interact with simulated HIV prevention interventions (e.g., syringe exchange programs, substance abuse treatment, HIV testing) and initiate antiretroviral treatment (ART) in a stochastic manner. The model was constructed to represent the New York metropolitan statistical area (MSA) population, and calibrated by comparing output trajectories for various outcomes (e.g., IDU/NIDU prevalence, HIV prevalence and incidence) against previously validated MSA-level data. The model closely approximated HIV trajectories in IDU and NIDU observed in New York City between 1992 and 2002, including a linear decrease in HIV prevalence among IDUs. Exploratory results are consistent with empirical studies demonstrating that the effectiveness of a combination of interventions, including syringe exchange expansion and ART provision, dramatically reduced HIV prevalence among IDUs during this time period. CONCLUSIONS/SIGNIFICANCE: Complex systems models of adaptive HIV transmission dynamics can be used to identify potential collective benefits of hypothetical combination prevention interventions. Future work will seek to inform novel strategies that may lead to more effective and equitable HIV prevention strategies for drug-using populations.",2012,13/11/2018 10:47,14/04/2020 08:34,,e44833,,9,7,,PLoS One,,,,,,,,eng,,,,,,,PMID: 23028637 PMCID: PMC3441492,,,,"Humans; Female; Male; Models, Statistical; Risk; Cities/*statistics & numerical data; Communicable Disease Control/*methods/*statistics & numerical data; Drug Users/statistics & numerical data; HIV Infections/epidemiology/*prevention & control/transmission; Homosexuality/statistics & numerical data; Injections; Risk-Taking; 1; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Y62GEZN2,journalArticle,2018,"Earnshaw, Stephanie R.",Are We Ready to Use Constrained Optimization in Health Outcomes Research?,Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research,,1524-4733 1098-3015,10.1016/j.jval.2018.07.004,,,2018-09,13/11/2018 10:47,14/04/2020 08:34,,1029-1030,,9,21,,Value Health,,,,,,,,eng,,,,,,,PMID: 30224104,,,,Humans; Outcome Assessment (Health Care)/*methods; Research Design/*trends; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GYRBH4RT,journalArticle,2018,"Mauro, Ann Marie P.; Tracey, Debora L.; LoGrippo, Maria Torchia; Anderson, Sharon; Bravo, Angelica; Byrne, Claire; Geissler, Bonnie; Escallier, Lori A.",Simulation Innovation to Redesign the Baccalaureate Curriculum to Address Population Health.,Nurse educator,,1538-9855 0363-3624,10.1097/NNE.0000000000000494,,"Prelicensure nursing curricula need to be redesigned to integrate and achieve key population health competencies. Nursing students in generic and second-degree programs had improved learning outcomes and significant increases in population health competencies across the curriculum using simulation-based learning activities developed through an academic-practice partnership. Simulation is an effective, interactive strategy that enhances student knowledge, skills, and competencies in addressing population health.",2018-10,13/11/2018 10:47,14/04/2020 08:34,,232-237,,5,43,,Nurse Educ,,,,,,,,eng,,,,,,,PMID: 30141779,,,,"Humans; *Curriculum; *Diffusion of Innovation; *Population Health; *Simulation Training; Adult; Clinical Competence; Education, Nursing, Baccalaureate/*organization & administration; Female; Learning; Male; Middle Aged; Nursing Education Research; Nursing Evaluation Research; Students, Nursing/psychology/statistics & numerical data; Young Adult; Curriculum; Public Health; Students; Patient Simulation; Nursing; Education; Analysis of Variance; Human; Pretest-Posttest Design; Descriptive Research; Baccalaureate; Cultural Competence; Data Analysis Software; Middle Age; Scales; Social Determinants of Health; T-Tests; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, M6SIE3BG,journalArticle,2018,"Tanz, Michele","Improving Safety Knowledge, Skills, and Attitudes With a Good Catch Program and Student-Designed Simulation.",The Journal of nursing education,,1938-2421 0148-4834,10.3928/01484834-20180522-11,,"BACKGROUND: This quality improvement project aimed to increase undergraduate nursing students' knowledge, skills, and attitudes (KSAs) relevant to the Quality and Safety Education for Nurses competency of safety, which was identified as a critical performance area. The question that this project examined was, Can incorporating chosen interventions into the course curriculum increase student KSAs of safety? METHOD: Two interventions were incorporated into the curriculum to increase student competency: a student-designed simulation project (SDSP), and a Good Catch and Error Reporting (GCER) program. A nonintervention group (n = 16) and an intervention group (n = 33) were evaluated with a dependent sample t test (pre- and posttest design) using the QUISKA2 Assessment Tool. RESULTS: For the intervention group (n = 33), the project interventions were found to be statistically significant t(32) = 6.14, p < .05. In addition, mean scores increased by 37%, whereas the nonintervention group increased by only 12%. CONCLUSION: The SDSP and GCER program were beneficial in improving students' KSAs regarding safety in health care. Students designed scenarios that addressed medication errors, critical team communication, prioritization, and handoff reporting using their own creativity to deliver valuable information to the entire clinical group. Implementing the GCER program helped create a culture of safety within this clinical section and helped to build student confidence in the quality improvement process. [J Nurs Educ. 2018;57(6):379-384.].",01/06/2018,13/11/2018 10:47,14/04/2020 08:35,,379-384,,6,57,,J Nurs Educ,,,,,,,,eng,"Copyright 2018, SLACK Incorporated.",,,,,,PMID: 29863741,,,,"Humans; Education, Nursing, Baccalaureate/*organization & administration; Nursing Education Research; Nursing Evaluation Research; *Quality Improvement; *Safety; Clinical Competence/*statistics & numerical data; Curriculum; Simulation Training; Students, Nursing/*psychology; Quality Improvement; Students; Nursing; Education; Descriptive Statistics; Human; P-Value; Pretest-Posttest Design; Data Analysis Software; Scales; T-Tests; Simulations; Coefficient Alpha; Competency Assessment; Curriculum Development; Education Research; Patient Safety – Education; Repeated Measures; Student Knowledge; Summated Rating Scaling; Vignettes; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DITXJTHK,journalArticle,2018,"Yang, Lan; Wang, Jing; Cheng, Juan; Wang, Yuan; Lu, Wenli",Quality assurance target for community-based breast cancer screening in China: a model simulation.,BMC cancer,,1471-2407 1471-2407,10.1186/s12885-018-4168-1,,"BACKGROUND: We aimed to clarify the feasibility of a community-based screening strategy for breast cancer in Tianjin, China; to identify the factors that most significantly influenced its feasibility; and to identify the reference range for quality control. METHODS: A state-transition Markov model simulated a hypothetical cohort of 100,000 healthy women, the start aged was set at 35 years and the time horizon was set to 50 years. The primary outcome for the model was the incremental cost-utility ratio (ICUR), defined as the program's cost per quality-adjusted life year (QALY) gained. Three screening strategies providing by community health service for women aged 35 to 69 years was compared regarding to different intervals. RESULT: The probability of the ICUR being below 20 272USD (i.e., triple the annual gross domestic product [3 GDPs]) per QALY saved was 100% for annual screening strategy and screening every three years. Only when the attendance rate was > 50%, the probability for annual screening would be cost effective > 95%. The probability for the annual screening strategy being cost effective could reach to 95% for a willingness-to-pay (WTP) of 2 GDPs when the compliance rate for transfer was > 80%. When 10% stage I tumors were detected by screening, the probability of the annual screening strategy being cost effective would be up to 95% for a WTP > 3 GDPs. CONCLUSION: Annual community-based breast cancer screening was cost effective for a WTP of 3 GDP based on the incidence of breast cancer in Tianjin, China. Measures are needed to ensure performance indicators to a desirable level for the cost-effectiveness of breast cancer screening.",07/03/2018,13/11/2018 10:47,14/04/2020 08:35,,261,,1,18,,BMC Cancer,,,,,,,,eng,,,,,,,PMID: 29514679 PMCID: PMC5840933,,,,"Humans; Health Services Research; Quality-Adjusted Life Years; Adult; Female; Middle Aged; *Breast cancer; *Cost-Benefit Analysis; *Cost-effective; *Models, Economic; *Quality-Adjusted Life Years; *Screening; Aged; Breast Neoplasms/*diagnosis/economics/epidemiology; China/epidemiology; Cohort Studies; Community-Based Participatory Research; Early Detection of Cancer/*economics; Follow-Up Studies; Markov Chains; Prognosis; China; Prospective Studies; Probability; Human; Comparative Studies; Models; Middle Age; Cost Benefit Analysis; Evaluation Research; Multicenter Studies; Validation Studies; Statistical; Ferrans and Powers Quality of Life Index; Breast Neoplasms – Diagnosis; Breast Neoplasms – Economics; Breast Neoplasms – Epidemiology; Early Detection of Cancer – Economics; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5EJD9GRY,journalArticle,2018,"Jupp, P. W.",A complex systems approach to cancer prevention.,Medical hypotheses,,1532-2777 0306-9877,10.1016/j.mehy.2018.01.006,,"Cancer incidence continues to be a major health problem possibly because cancer is a complex system comprising many agents that interact in a non-linear manner resulting in many possible outcomes. The degree of complexity of a cancer system could be vast involving multiple endogenous and exogenous agents interacting with the over 10 trillion cells comprising the body. It is hypothesized that the practical management of this complexity may be a key to cancer prevention and possibly treatment. But the management and resolution of such an immensely complex system is difficult and may require a multidisciplinary approach including physics, biology, biochemistry and medical science. Research such as in systems biology involving large data sets may offer resolution in time, but the scale of the task is daunting. In evaluating the hypothesis, this paper proposes a method of resolution of the complex cancer system through a proxy in the form of the vital body system, energy balance, involved in several cancer processes. Although I suggest that the energy balance system is itself complex, it may permit access to factors that may be used in limiting cancer initiation. Meta-analysis related to factors of blood sugar, inflammation, stress and immune response reveal that they could be likely candidates for management. Analysis also reveals certain devices that may give practical effect to these management options. Due to the inherent complexity of a cancer system, multiple devices may need to be applied in a combination. The analysis suggests that the low-risk and low-cost devices metformin, vitamin D and vitamin C, may prove to be suitable for use as a practical cancer prevention strategy. If the presented hypothesis is correct, a practical method for prevention or management of cancer may be possible. A trial to test the hypothesis is proposed.",2018-03,13/11/2018 10:47,14/04/2020 08:34,,18-23,,,112,,Med Hypotheses,,,,,,,,eng,Copyright (c) 2018 Elsevier Ltd. All rights reserved.,,,,,,PMID: 29447929,,,,"Humans; Decision Support Techniques; *Models, Biological; Exercise; Meta-Analysis as Topic; Systems Theory; *Systems Theory; Diet; *Energy Metabolism/drug effects; beta-Glucans/administration & dosage/pharmacology/therapeutic use; Cancer prevention; Complex energy balance; Complexity; Drug Synergism; Glucose/metabolism; Homeostasis; Inflammation; Melatonin/administration & dosage/pharmacology/therapeutic use; Metformin/administration & dosage/pharmacology/therapeutic use; Neoplasms/immunology/metabolism/*prevention & control; Stress; Stress, Physiological; Vitamins/administration & dosage/pharmacology/therapeutic use; 1; Models; Beta-Glucans – Administration and Dosage; Beta-Glucans – Pharmacodynamics; Beta-Glucans – Therapeutic Use; Biological; Energy Metabolism – Drug Effects; Glucose – Metabolism; Melatonin – Administration and Dosage; Melatonin – Pharmacodynamics; Melatonin – Therapeutic Use; Metformin – Administration and Dosage; Metformin – Pharmacodynamics; Metformin – Therapeutic Use; Neoplasms – Immunology; Neoplasms – Metabolism; Neoplasms – Prevention and Control; Physiological; Vitamins – Administration and Dosage; Vitamins – Pharmacodynamics; Vitamins – Therapeutic Use; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9FG5SVR9,journalArticle,2018,"Nelson, Sara W.; Germann, Carl A.; MacVane, Casey Z.; Bloch, Rebecca B.; Fallon, Timothy S.; Strout, Tania D.",Intern as Patient: A Patient Experience Simulation to Cultivate Empathy in Emergency Medicine Residents.,The western journal of emergency medicine,,1936-9018 1936-900X,10.5811/westjem.2017.11.35198,,"Introduction: Prior work links empathy and positive physician-patient relationships to improved healthcare outcomes. The objective of this study was to analyze a patient experience simulation for emergency medicine (EM) interns as a way to teach empathy and conscientious patient care. Methods: We conducted a qualitative descriptive study on an in situ, patient experience simulation held during EM residency orientation. Half the interns were patients brought into the emergency department (ED) by ambulance and half were family members. Interns then took part in focus groups that discussed the experience. Data collected during these focus groups were coded by two investigators using a grounded theory approach and constant comparative methodology. Results: We identified 10 major themes and 28 subthemes in the resulting qualitative data. Themes were in three broad categories: the experience as a patient or family member in the ED; application to current clinical practice; and evaluation of the exercise itself. Interns experienced firsthand the physical discomfort, emotional stress and confusion patients and families endure during the ED care process. They reflected on lessons learned, including the importance of good communication skills, frequent updates on care and timing, and being responsive to the needs and concerns of patients and families. All interns felt this was a valuable orientation experience. Conclusion: Conducting a patient experience simulation may be a practical and effective way to develop empathy in EM resident physicians. Additional research evaluating the effect of participation in the simulation over a longer time period and assessing the effects on residents' actual clinical care is warranted.",2018-01,13/11/2018 10:47,14/04/2020 08:35,,41-48,,1,19,,West J Emerg Med,,,,,,,,eng,,,,,,,PMID: 29383055 PMCID: PMC5785200,,,,"Humans; Female; Male; *Patient Simulation; *Empathy; *Physician-Patient Relations; Education, Medical, Graduate; Emergency Medicine/*education; Emergency Service, Hospital; Focus Groups; Grounded Theory; Internship and Residency/*methods; Patient-Centered Care; Qualitative Research; Patient Care; Patient Simulation; Empathy; Stress; Human; Ambulances; Confusion; Descriptive Research; Emergency Care; Emergency Medicine; Emergency Service; Exercise – Evaluation; Extended Family; Interns and Residents – Psychosocial Factors; Patient Attitudes; Psychological; Qualitative Studies; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4GB6MF3W,journalArticle,2018,"Roberts, Samantha; Craig, Dawn; Adler, Amanda; McPherson, Klim; Greenhalgh, Trisha",Economic evaluation of type 2 diabetes prevention programmes: Markov model of low- and high-intensity lifestyle programmes and metformin in participants with different categories of intermediate hyperglycaemia.,BMC medicine,,1741-7015 1741-7015,10.1186/s12916-017-0984-4,,"BACKGROUND: National guidance on preventing type 2 diabetes mellitus (T2DM) in the UK recommends low-intensity lifestyle interventions for individuals with intermediate categories of hyperglycaemia defined in terms of impaired fasting glucose (IFG) or 'at-risk' levels of HbA1c. In a recent systematic review of economic evaluations of such interventions, most studies had evaluated intensive trial-based lifestyle programmes in participants with impaired glucose tolerance (IGT). This study examines the costs and effects of different intensity lifestyle programmes and metformin in participants with different categories of intermediate hyperglycaemia. METHODS: We developed a decision tree and Markov model (50-year horizon) to compare four approaches, namely (1) a low-intensity lifestyle programme based on current NICE guidance, (2) a high-intensity lifestyle programme based on the US Diabetes Prevention Program, (3) metformin, and (4) no intervention, modelled for three different types of intermediate hyperglycaemia (IFG, IGT and HbA1c). A health system perspective was adopted and incremental analysis undertaken at an individual and population-wide level, taking England as a case study. RESULTS: Low-intensity lifestyle programmes were the most cost-effective ( pound44/QALY, pound195/QALY and pound186/QALY compared to no intervention in IGT, IFG and HbA1c, respectively). Intensive lifestyle interventions were also cost-effective compared to no intervention ( pound2775/QALY, pound6820/QALY and pound7376/QALY, respectively, in IGT, IFG and HbA1c). Metformin was cost-effective relative to no intervention ( pound5224/QALY, pound6842/QALY and pound372/QALY in IGT, IFG and HbA1c, respectively), but was only cost-effective relative to other treatments in participants identified with HbA1c. At a willingness-to-pay threshold of pound20,000/QALY, low- and high-intensity lifestyle programmes were cost-effective 98%, 99% and 98% and 81%, 81% and 71% of the time in IGT, IFG and HbA1c, respectively. An England-wide programme for 50-59 year olds could reduce T2DM incidence by < 3.5% over 50 years and would cost 0.2-5.2% of the current diabetes budget for 2-9 years. DISCUSSION: This analysis suggests that current English national policy of low-intensity lifestyle programmes in participants with IFG or HbA1c will be cost-effective and have the most favourable budget impact, but will prevent only a fraction of cases of T2DM. Additional approaches to prevention need to be investigated urgently.",30/01/2018,13/11/2018 10:47,14/04/2020 08:35,,16,,1,16,,BMC Med,,,,,,,,eng,,,,,,,PMID: 29378576 PMCID: PMC5798197,,,,"Humans; Cost-Benefit Analysis; Female; Male; *Cost-effective; *Economic evaluation; *Diabetes prevention; *HbA1c in at-risk range; *Impaired fasting glucose; *Impaired glucose tolerance; *Intermediate hyperglycaemia; *Prediabetes; Diabetes Mellitus, Type 2/*economics/prevention & control; Hyperglycemia/*drug therapy; Metformin/*economics/*therapeutic use; 1; Human; Comparative Studies; Cost Benefit Analysis; Metformin – Therapeutic Use; Funding Source; Evaluation Research; Multicenter Studies; Validation Studies; Diabetes Mellitus; Hyperglycemia – Drug Therapy; Metformin – Economics; Type 2 – Economics; Type 2 – Prevention and Control; Markov; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ABB57KPK,journalArticle,2018,"Pellegrin, Karen; Chan, Francis; Pagoria, Natalie; Jolson-Oakes, Sheena; Uyeno, Reece; Levin, Andrew",A Statewide Medication Management System: Health Information Exchange to Support Drug Therapy Optimization by Pharmacists across the Continuum of Care.,Applied clinical informatics,,1869-0327 1869-0327,10.1055/s-0037-1620262,,"BACKGROUND: While evidence generally supports the use of medication management technology, systems are typically implemented and evaluated piecemeal rather than as part of a comprehensive model for medication management. Systems to support drug therapy optimization, increasingly a key role of pharmacists in our healthcare system, have not yet been reported. OBJECTIVE: Our objective is to describe the design, implementation, and use of health information technology to support the hospital and community pharmacists' management of medications for high-risk patients statewide in the ""Pharm2Pharm"" model of care. Our aims were to make it easier for the pharmacists to access information needed to identify and resolve drug therapy problems using best practices for medication management and communicate with other members of the care team. METHODS: The pharmacist's roles and the medication management processes guided the design of the supporting technology, which was implemented after the Pharm2Pharm model was launched and the pharmacists' technology needs were assessed. Priorities for technology included sending care transition documents from hospital to community pharmacist securely and efficiently, access to medical records, including medications and laboratory results, documentation, and patient tracking. Implementation and use of the technology were documented. RESULTS: Communications, medication management, and population management solutions were implemented to support the Pharm2Pharm model. The pharmacists delivering services through this model adopted and meaningfully used this technology to support their work. CONCLUSION: Implementing technology with value outside of the Pharm2Pharm model was a strategic approach to investment. This work emphasizes the importance of shifting the focus of technology from supporting a specific piece of the medication management process to supporting the goal of optimizing medication regimens. Health information exchange systems can provide important technology needed to integrate pharmacists into care teams as they are deployed to improve patient outcomes.",2018-01,13/11/2018 10:47,14/04/2020 08:35,,01-Oct,,1,9,,Appl Clin Inform,,,,,,,,eng,Schattauer GmbH Stuttgart.,,,,,,PMID: 29298450 PMCID: PMC5801897,,,,Humans; Delivery of Health Care; *Continuity of Patient Care; *Drug Therapy; *Health Information Exchange; *Medication Therapy Management; *Pharmacists; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IKNBVDEK,journalArticle,2017,"Andersen, Patrea; Horton, Eleanor; Clarke, Karen Ann",IMPROVING HEALTH AND SAFETY IN AGED CARE USING GAME BASED SIMULATION.,Australian nursing & midwifery journal,,2202-7114 2202-7114,,,"Australia faces the challenge of supporting a growing ageing population (AIHW, 2012). Health and safety is paramount in ensuring care is economically sustainable. Nurses involved in healthcare have a responsibility to protect themselves and those being cared for against health and safety risk. Training of the workforce is paramount to reducing the chance of injury (Robson et al. 2012).",2017-02,13/11/2018 10:47,14/04/2020 08:34,,35,,7,24,,Aust Nurs Midwifery J,,,,,,,,eng,,,,,,,PMID: 29257640,,,,Humans; Aged; *Geriatric Nursing; *Independent Living; *Risk Assessment; *Software; *Virtual Reality; Facility Design and Construction; Safety; Wounds and Injuries/*prevention & control; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MDAUV4MJ,journalArticle,2017,"Eisenberg, John M.",Continuing Education Meets the Learning Organization: The Challenge of a Systems Approach to Patient Safety.,The Journal of continuing education in the health professions,,1554-558X 0894-1912,10.1097/CEH.0000000000000177,,"Since the release of the report of the Institute of Medicine on medical errors and patient safety in November 1999, health policy makers and health care leaders in several nations have sought solutions that will improve the safety of health care. This attention to patient safety has highlighted the importance of a learning approach and a systems approach to quality measurement and improvement. Balanced with the need for public disclosure of performance, confidential reporting with feedback is one of the prime ways that nations such as the United States, Canada, the United Kingdom, and Australia have approached this challenge. In the United States, the Quality Interagency Coordination Task Force has convened federal agencies that are involved in health care quality improvement for a coordinated initiative. Based on an investment in a strong research foundation in health care quality measurement and improvement, there are eight key lessons for continuing education if it is to parlay the interest in patient safety into enhanced continuing education and quality improvement in learning health care systems. The themes for these lessons are (1) informatics for information, (2) guidelines as learning tools, (3) learning from opinion leaders, (4) learning from the patient, (5) decision support systems, (6) the team learning together, (7) learning organizations, and (8) just-in-time and point-of care delivery.",2017,13/11/2018 10:47,14/04/2020 08:34,,255-261,,4,37,,J Contin Educ Health Prof,,,,,,,,eng,,,,,,,PMID: 29227430,,,,"Humans; Quality of Health Care; Patient Safety/*standards; Patient Safety; *Systems Analysis; Cross Infection/epidemiology; Education, Continuing/*methods/standards; Medical Errors/*prevention & control/trends; Quality Indicators, Health Care/statistics & numerical data; Staff Development/methods; Quality Improvement; Organizational Culture; Education; Medical; Continuing (Credit); Adverse Health Care Event – Prevention and Control; Continuing – Standards; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TS97F6AU,journalArticle,2017,"Wenger, Nanette K.; Doherty, Caroline Lloyd; Gurwitz, Jerry H.; Hirsch, Glenn A.; Holmes, Holly M.; Maurer, Matthew S.; Murray, Michael D.",Optimization of Drug Prescription and Medication Management in Older Adults with Cardiovascular Disease.,Drugs & aging,,1179-1969 1170-229X,10.1007/s40266-017-0494-2,,"Cardiovascular disease increases incrementally with age and elderly patients concomitantly sustain multimorbidities, with resultant prescription of multiple medications. Despite conforming with disease-specific cardiovascular clinical practice guidelines, this polypharmacy predisposes many elderly individuals with cardiovascular disease to adverse drug events and non-adherence. Patient-centered care requires that the clinician explore with each patient his or her goals of care and that this shared decision-making constitutes the basis for optimization of medication management. This approach to aligning therapies with patient preferences is likely to promote patient satisfaction, to limit morbidity, and to favorably affect healthcare costs.",2017-11,13/11/2018 10:47,14/04/2020 08:35,,803-810,,11,34,,Drugs Aging,,,,,,,,eng,,,,,,,PMID: 29110264,,,,Humans; Patient Satisfaction; Health Care Costs; Adult; Female; Aged; Patient-Centered Care; Cardiovascular Diseases/*drug therapy; Decision Making; Drug Interactions; Drug Prescriptions/*standards; Drug-Related Side Effects and Adverse Reactions/*prevention & control; Medication Adherence; Medication Therapy Management/*organization & administration/standards; Patient Preference; Polypharmacy; 1; Patient Centered Care; 80 and Over; Adverse Drug Event – Risk Factors; Cardiovascular Diseases – Drug Therapy – In Old Age; Comorbidity – In Old Age; Medication Compliance; Medication Management – In Old Age; Polypharmacy – Adverse Effects; Shared; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FUBHV8GX,journalArticle,2017,"Schmier, Jordana K.; Lau, Edmund C.; Patel, Jasmine D.; Klenk, Juergen A.; Greenspon, Arnold J.",Effect of battery longevity on costs and health outcomes associated with cardiac implantable electronic devices: a Markov model-based Monte Carlo simulation.,Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing,,1572-8595 1383-875X,10.1007/s10840-017-0289-8,,"INTRODUCTION: The effects of device and patient characteristics on health and economic outcomes in patients with cardiac implantable electronic devices (CIEDs) are unclear. Modeling can estimate costs and outcomes for patients with CIEDs under a variety of scenarios, varying battery longevity, comorbidities, and care settings. The objective of this analysis was to compare changes in patient outcomes and payer costs attributable to increases in battery life of implantable cardiac defibrillators (ICDs) and cardiac resynchronization therapy defibrillators (CRT-D). METHODS AND RESULTS: We developed a Monte Carlo Markov model simulation to follow patients through primary implant, postoperative maintenance, generator replacement, and revision states. Patients were simulated in 3-month increments for 15 years or until death. Key variables included Charlson Comorbidity Index, CIED type, legacy versus extended battery longevity, mortality rates (procedure and all-cause), infection and non-infectious complication rates, and care settings. Costs included procedure-related (facility and professional), maintenance, and infections and non-infectious complications, all derived from Medicare data (2004-2014, 5% sample). Outcomes included counts of battery replacements, revisions, infections and non-infectious complications, and discounted (3%) costs and life years. An increase in battery longevity in ICDs yielded reductions in numbers of revisions (by 23%), battery changes (by 44%), infections (by 23%), non-infectious complications (by 10%), and total costs per patient (by 9%). Analogous reductions for CRT-Ds were 23% (revisions), 32% (battery changes), 22% (infections), 8% (complications), and 10% (costs). CONCLUSION: Based on modeling results, as battery longevity increases, patients experience fewer adverse outcomes and healthcare costs are reduced. Understanding the magnitude of the cost benefit of extended battery life can inform budgeting and planning decisions by healthcare providers and insurers.",2017-11,13/11/2018 10:47,14/04/2020 08:35,,149-158,,2,50,,J Interv Card Electrophysiol,,,,,,,,eng,,,,,,,PMID: 29110166 PMCID: PMC5705743,,,,"Humans; United States; Outcome Assessment (Health Care); Cost-Benefit Analysis; Health Care Costs; Female; Male; Middle Aged; Aged; *Cost Savings; *Health Care Costs; Battery life; Cardiac resynchronization therapy devices; Cardiac Resynchronization Therapy Devices/economics; Costs and cost analysis; Defibrillators, Implantable/*economics/utilization; Device battery replacement; Device longevity; Device Removal/economics; Electric Power Supplies/adverse effects/*economics; Equipment Failure/economics; Heart Failure/economics/therapy; Medicare/economics; Monte Carlo Method; Systems Analysis; Cost Savings; Human; Comparative Studies; Middle Age; Cost Benefit Analysis; Outcome Assessment; Artificial – Economics; Defibrillators; Device Removal – Economics; Equipment Failure – Economics; Evaluation Research; Heart Failure – Economics; Heart Failure – Therapy; Implantable – Economics; Implantable – Utilization; Medicare – Economics; Multicenter Studies; Pacemaker; Power Sources – Adverse Effects; Power Sources – Economics; Validation Studies; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Q9CNJXLB,journalArticle,2017,"Moessner, Markus; Bauer, Stephanie",Maximizing the public health impact of eating disorder services: A simulation study.,The International journal of eating disorders,,1098-108X 0276-3478,10.1002/eat.22792,,"OBJECTIVE: Although effective interventions for eating disorders (ED) are available, the impact of health care services on a population level is far from satisfactory. A mathematical model of how health care for ED affects the population's disease burden can stimulate discussions and provide guidance about promising strategies to reduce ED-related suffering on the population level. METHOD: The current health care situation for ED is modeled taking into account the reach and effectiveness of prevention, treatment, and aftercare, as well as incidence rates, relapse rates, and rates for spontaneous remissions. A first-order Markov model is applied and the effect of changes in single service parameters on the populations overall disease burden are simulated. RESULTS: Improvements of treatment utilization and the reach of prevention programs would have the largest effects on the population's disease burden. Improving the efficacy of treatment, prevention, and aftercare show only limited effects. DISCUSSION: In order to maximize the public health impact of health care for ED new models of treatment delivery as well as public health approaches to the prevention of ED are critical.",2017-12,13/11/2018 10:47,14/04/2020 08:34,,1378-1384,,12,50,,Int J Eat Disord,,,,,,,,eng,"(c) 2017 Wiley Periodicals, Inc.",,,,,,PMID: 29076172,,,,Humans; Health Services Research; *burden of suffering; *eating disorders; *public health; *service research; *simulation; Chronic Disease; Feeding and Eating Disorders/*diagnosis; Public Health/*methods; Public Health; 1; Human; Models; Simulations; Eating Disorders – Therapy; Statistical; Markov; 210,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9LM9FNBS,journalArticle,2017,"Famiglietti, Robin M.; Norboge, Emily C.; Boving, Valentine; Langabeer, James R. 2nd; Buchholz, Thomas A.; Mikhail, Osama",Using Discrete-Event Simulation to Promote Quality Improvement and Efficiency in a Radiation Oncology Treatment Center.,Quality management in health care,,1550-5154 1063-8628,10.1097/QMH.0000000000000145,,"BACKGROUND: To meet demand for radiation oncology services and ensure patient-centered safe care, management in an academic radiation oncology department initiated quality improvement efforts using discrete-event simulation (DES). Although the long-term goal was testing and deploying solutions, the primary aim at the outset was characterizing and validating a computer simulation model of existing operations to identify targets for improvement. METHODS: The adoption and validation of a DES model of processes and procedures affecting patient flow and satisfaction, employee experience, and efficiency were undertaken in 2012-2013. Multiple sources were tapped for data, including direct observation, equipment logs, timekeeping, and electronic health records. RESULTS: During their treatment visits, patients averaged 50.4 minutes in the treatment center, of which 38% was spent in the treatment room. Patients with appointments between 10 AM and 2 PM experienced the longest delays before entering the treatment room, and those in the clinic in the day's first and last hours, the shortest (<5 minutes). Despite staffed for 14.5 hours daily, the clinic registered only 20% of patients after 2:30 PM. Utilization of equipment averaged 58%, and utilization of staff, 56%. CONCLUSION: The DES modeling quantified operations, identifying evidence-based targets for next-phase remediation and providing data to justify initiatives.",2017-12,13/11/2018 10:47,14/04/2020 08:34,,184-189,,4,26,,Qual Manag Health Care,,,,,,,,eng,,,,,,,PMID: 28991813,,,,"Humans; Patient Satisfaction; Reproducibility of Results; *Quality Improvement; *Efficiency, Organizational; *Radiation Oncology; Ambulatory Care Facilities; Appointments and Schedules; Cancer Care Facilities/*organization & administration; Computer Simulation; Electronic Health Records; Resource Allocation; Time; Time Factors; Quality Improvement; Confidence Intervals; Descriptive Statistics; Human; P-Value; Health Care Delivery; Conceptual Framework; Patient Centered Care; Funding Source; Nonexperimental Studies; Observational Methods; Radiation Oncology; Sample Size; 00; Review",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7YXVL6FT,journalArticle,2017,"Nelissen, Ellen; Ersdal, Hege; Mduma, Estomih; Evjen-Olsen, Bjorg; Twisk, Jos; Broerse, Jacqueline; van Roosmalen, Jos; Stekelenburg, Jelle",Clinical performance and patient outcome after simulation-based training in prevention and management of postpartum haemorrhage: an educational intervention study in a low-resource setting.,BMC pregnancy and childbirth,,1471-2393 1471-2393,10.1186/s12884-017-1481-7,,"BACKGROUND: Postpartum haemorrhage (PPH) is a major cause of maternal mortality. Prevention and adequate treatment are therefore important. However, most births in low-resource settings are not attended by skilled providers, and knowledge and skills of healthcare workers that are available are low. Simulation-based training effectively improves knowledge and simulated skills, but the effectiveness of training on clinical behaviour and patient outcome is not yet fully understood. The aim of this study was to assess the effect of obstetric simulation-based training on the incidence of PPH and clinical performance of basic delivery skills and management of PPH. METHODS: A prospective educational intervention study was performed in a rural referral hospital in Tanzania. Sixteen research assistants observed all births with a gestational age of more than 28 weeks from May 2011 to June 2013. In March 2012 a half-day obstetric simulation-based training in management of PPH was introduced. Observations before and after training were compared. The main outcome measures were incidence of PPH (500-1000 ml and >1000 ml), use and timing of administration of uterotonic drugs, removal of placenta by controlled cord traction, uterine massage, examination of the placenta, management of PPH (>500 ml), and maternal and neonatal mortality at 24 h. RESULTS: Three thousand six hundred twenty two births before and 5824 births after intervention were included. The incidence of PPH (500-1000 ml) significantly reduced from 2.1% to 1.3% after training (effect size Cohen's d = 0.07). The proportion of women that received oxytocin (87.8%), removal of placenta by controlled cord traction (96.5%), and uterine massage after birth (93.0%) significantly increased after training (to 91.7%, 98.8%, 99.0% respectively). The proportion of women who received oxytocin as part of management of PPH increased significantly (before training 43.0%, after training 61.2%). Other skills in management of PPH improved (uterine massage, examination of birth canal, bimanual uterine compression), but these were not statistically significant. CONCLUSIONS: The introduction of obstetric simulation-based training was associated with a 38% reduction in incidence of PPH and improved clinical performance of basic delivery skills and management of PPH.",11/09/2017,13/11/2018 10:47,14/04/2020 08:35,,301,,1,17,,BMC Pregnancy Childbirth,,,,,,,,eng,,,,,,,PMID: 28893211 PMCID: PMC5594489,,,,Humans; *Simulation Training; Clinical Competence; Female; Pregnancy; Low-resource settings; Prospective Studies; Health Personnel/*education; Tanzania; Patient Outcome Assessment; Simulation-based training; Education; *Developing Countries; Blood Volume; Massage; Maternal Death/etiology; Obstetrics; Oxytocics/therapeutic use; Oxytocin/therapeutic use; Postpartum haemorrhage; Postpartum Hemorrhage/*prevention & control/*therapy; Human; Postpartum Hemorrhage – Therapy; Outcome Assessment; Developing Countries; Health Personnel – Education; Maternal Mortality – Etiology; Oxytocics – Therapeutic Use; Oxytocin – Therapeutic Use; Postpartum Hemorrhage – Prevention and Control; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EKYK862R,journalArticle,2017,"Griffith, John R.",An Organizational Model for Excellence in Healthcare Delivery: Evidence From Winners of the Baldrige Quality Award.,Journal of healthcare management / American College of Healthcare Executives,,1096-9012 1096-9012,10.1097/JHM-D-16-00011,,"EXECUTIVE SUMMARY: Winners of the Baldrige National Quality Award in healthcare have documented top quartile clinical outcomes and patient satisfaction across a variety of American communities and a full spectrum of care. Their results also show high levels of satisfaction among physicians, nurses, and other workers, as well as effective financial performance. The managerial methods they use-collectively, the Baldrige model-are consistent with organizational theory literature and are found across all winners. The winners have sustained excellence after winning and expanded it by acquisition of other healthcare organizations.The model differs substantially from traditional management approaches in healthcare delivery. It is a comprehensive program that emphasizes a shared focus on excellence, systematically responsive management, evidence-based medicine, multidimensional measures and negotiated goals, improvement of work processes, thorough training, and extensive rewards. The model could be expanded on a much larger scale. Doing so successfully would substantially improve the quality and cost of healthcare, as well as the satisfaction and commitment of care providers and other staff. The opportunity deserves further study and trial by large healthcare delivery systems, insurers, and consulting companies.",2017-10,13/11/2018 10:47,14/04/2020 08:34,,328-341,,5,62,,J Healthc Manag,,,,,,,,eng,,,,,,,PMID: 28885534,,,,"Humans; Patient Satisfaction; *Delivery of Health Care; *Models, Organizational; Awards and Prizes; 1; Health Care Delivery; Conceptual Framework; Organizational Change; Awards and Honors; Excellence; Health Facility Administration; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HJBHECJA,journalArticle,2017,"Li, Yan; Padron, Norma A.; Mangla, Anil T.; Russo, Pamela G.; Schlenker, Thomas; Pagan, Jose A.","Using Systems Science to Inform Population Health Strategies in Local Health Departments: A Case Study in San Antonio, Texas.","Public health reports (Washington, D.C. : 1974)",,1468-2877 0033-3549,10.1177/0033354917722149,,"OBJECTIVES: Because of state and federal health care reform, local health departments play an increasingly prominent role leading and coordinating disease prevention programs in the United States. This case study shows how a local health department working in chronic disease prevention and management can use systems science and evidence-based decision making to inform program selection, implementation, and assessment; enhance engagement with local health systems and organizations; and possibly optimize health care delivery and population health. METHODS: The authors built a systems-science agent-based simulation model of diabetes progression for the San Antonio Metropolitan Health District, a local health department, to simulate health and cost outcomes for the population of San Antonio for a 20-year period (2015-2034) using 2 scenarios: 1 in which hemoglobin A1c (HbA1c) values for a population were similar to the current distribution of values in San Antonio, and the other with a hypothetical 1-percentage-point reduction in HbA1c values. RESULTS: They projected that a 1-percentage-point reduction in HbA1c would lead to a decrease in the 20-year prevalence of end-stage renal disease from 1.7% to 0.9%, lower extremity amputation from 4.6% to 2.9%, blindness from 15.1% to 10.7%, myocardial infarction from 23.8% to 17.9%, and stroke from 9.8% to 7.2%. They estimated annual direct medical cost savings (in 2015 US dollars) from reducing HbA1c by 1 percentage point ranging from $6842 (myocardial infarction) to $39 800 (end-stage renal disease) for each averted case of diabetes complications. CONCLUSIONS: Local health departments could benefit from the use of systems science and evidence-based decision making to estimate public health program effectiveness and costs, calculate return on investment, and develop a business case for adopting programs.",2017-10,13/11/2018 10:47,14/04/2020 08:34,,549-555,,5,132,,Public Health Rep,,,,,,,,eng,,,,,,,PMID: 28813636 PMCID: PMC5593239,,,,"Humans; *Cost-Benefit Analysis; *agent-based modeling; *Systems Analysis; Decision Making; Public Health/*methods; Systems Analysis; *diabetes; *Disease Management; *local health departments; *population health; *systems science; Behavioral Risk Factor Surveillance System; Chronic Disease/economics; Diabetes Complications/economics; Diabetes Mellitus/economics; Models, Statistical; Organizational Case Studies; Texas; Public Health; Cost Savings; 1; Human; Health Care Delivery; Amputation; Blindness – Prevention and Control; Chronic – Prevention and Control; Chronic Disease – Prevention and Control – Texas; Computer Simulation – Utilization; Diabetes Mellitus – Prevention and Control; Evidence-Based; Glycosylated – Blood; Government Agencies – Texas; Health Policy – Texas; Hemoglobin A; Kidney Failure; Myocardial Infarction – Prevention and Control; Policy Making – Methods – Texas; Professional Practice; Public Health – Texas; Stroke – Prevention and Control; 320; agent-based",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QKK5NFFS,journalArticle,2018,"Lee, Monghyeon; Chun, Yongwan; Griffith, Daniel A.","Error propagation in spatial modeling of public health data: a simulation approach using pediatric blood lead level data for Syracuse, New York.",Environmental geochemistry and health,,1573-2983 0269-4042,10.1007/s10653-017-0014-7,,"Lead poisoning produces serious health problems, which are worse when a victim is younger. The US government and society have tried to prevent lead poisoning, especially since the 1970s; however, lead exposure remains prevalent. Lead poisoning analyses frequently use georeferenced blood lead level data. Like other types of data, these spatial data may contain uncertainties, such as location and attribute measurement errors, which can propagate to analysis results. For this paper, simulation experiments are employed to investigate how selected uncertainties impact regression analyses of blood lead level data in Syracuse, New York. In these simulations, location error and attribute measurement error, as well as a combination of these two errors, are embedded into the original data, and then these data are aggregated into census block group and census tract polygons. These aggregated data are analyzed with regression techniques, and comparisons are reported between the regression coefficients and their standard errors for the error added simulation results and the original results. To account for spatial autocorrelation, the eigenvector spatial filtering method and spatial autoregressive specifications are utilized with linear and generalized linear models. Our findings confirm that location error has more of an impact on the differences than does attribute measurement error, and show that the combined error leads to the greatest deviations. Location error simulation results show that smaller administrative units experience more of a location error impact, and, interestingly, coefficients and standard errors deviate more from their true values for a variable with a low level of spatial autocorrelation. These results imply that uncertainty, especially location error, has a considerable impact on the reliability of spatial analysis results for public health data, and that the level of spatial autocorrelation in a variable also has an impact on modeling results.",2018-04,13/11/2018 10:47,14/04/2020 08:34,,667-681,,2,40,,Environ Geochem Health,,,,,,,,eng,,,,,,,PMID: 28791510,,,,Humans; *Public Health; Child; *Geographic Mapping; *Uncertainty; Lead poisoning; Lead Poisoning/blood/epidemiology; Lead/*blood; Linear Models; Location error; Measurement error; New York/epidemiology; Spatial data analysis; Uncertainty; 00; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MLKG5SRK,journalArticle,2018,"Standfield, Lachlan B.; Comans, Tracy; Scuffham, Paul",A simulation of dementia epidemiology and resource use in Australia.,Australian and New Zealand journal of public health,,1753-6405 1326-0200,10.1111/1753-6405.12700,,"OBJECTIVES: The number of people in the developed world who have dementia is predicted to rise markedly. This study presents a validated predictive model to assist decision-makers to determine this population's future resource requirements and target scarce health and welfare resources appropriately. METHODS: A novel individual patient discrete event simulation was developed to estimate the future prevalence of dementia and related health and welfare resource use in Australia. RESULTS: When compared to other published results, the simulation generated valid estimates of dementia prevalence and resource use. The analysis predicted 298,000, 387,000 and 928,000 persons in Australia will have dementia in 2011, 2020 and 2050, respectively. Health and welfare resource use increased markedly over the simulated time-horizon and was affected by capacity constraints. CONCLUSIONS: This simulation provides useful estimates of future demands on dementia-related services allowing the exploration of the effects of capacity constraints. Implications for public health: The model demonstrates that under-resourcing of residential aged care may lead to inappropriate and inefficient use of hospital resources. To avoid these capacity constraints it is predicted that the number of aged care beds for persons with dementia will need to increase more than threefold from 2011 to 2050.",2018-06,13/11/2018 10:47,14/04/2020 08:34,,291-295,,3,42,,Aust N Z J Public Health,,,,,,,,eng,(c) 2017 The Authors.,,,,,,PMID: 28749604,,,,Humans; Forecasting; Aged; Decision Making; Computer Simulation; Australia; Prevalence; epidemiology; Australia/epidemiology; discrete event simulation; dementia; Dementia/*epidemiology; Health Resources/*utilization; resource use; 1; ****; Human; Clinical; Dementia – Epidemiology – Australia; Health and Welfare Planning; Health Resource Utilization; 310,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KZ4YZBVY,journalArticle,2017,"Brimble, Mandy; Jones, Aled",Using systems thinking in patient safety: a case study on medicines management.,"Nursing management (Harrow, London, England : 1994)",,1354-5760 1354-5760,10.7748/nm.2017.e1621,,"Systems thinking is used as a way of understanding behaviours and actions in complex healthcare organisations. An important premise of the concept is that every action in a system causes a reaction elsewhere in that system. These reactions can lead to unintended consequences, sometimes long after the original action, and so are not always attributed to them. This article applies systems thinking to a medicines management case study, to highlight how quality-improvement practitioners can use the approach to underpin planning and implementation of patient-safety initiatives. The case study is specific to transcribing in children's hospices, but the strategies can be applied to other areas. The article explains that, while root cause analysis tools are useful for identifying the cause of, and possible solutions to, problems, they need to be considered carefully in terms of unintended consequences, and how the system into which the solution is implemented can be affected by the change. Analysis of problems using a systems-thinking approach can help practitioners to develop robust and well informed business cases to present to decision makers.",29/06/2017,13/11/2018 10:47,14/04/2020 08:34,,28-33,,4,24,,Nurs Manag (Harrow),,,,,,,,eng,,,,,,,PMID: 28659071,,,,Humans; Patient Safety; *Medication Therapy Management; Child; *Systems Analysis; *Patient Safety; medicines management; nursing management; patient safety; Quality Improvement; systems thinking; transcribing; unintended consequences; wicked issues; Hospitals; Adverse Health Care Event – Prevention and Control – In Infancy and Childhood; Hospice Care; Medication Errors – Prevention and Control – In Infancy and Childhood; Nursing Management; Pediatric; Root Cause Analysis; 00; ******To read; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, THRVH8QK,journalArticle,2017,"Rutter, Harry; Savona, Natalie; Glonti, Ketevan; Bibby, Jo; Cummins, Steven; Finegood, Diane T.; Greaves, Felix; Harper, Laura; Hawe, Penelope; Moore, Laurence; Petticrew, Mark; Rehfuess, Eva; Shiell, Alan; Thomas, James; White, Martin",The need for a complex systems model of evidence for public health.,"Lancet (London, England)",,1474-547X 0140-6736,10.1016/S0140-6736(17)31267-9,,,09/12/2017,13/11/2018 10:47,14/04/2020 08:35,,2602-2604,,10112,390,,Lancet,,,,,,,,eng,,,,,,,PMID: 28622953,,,,"Humans; Systems Analysis; *Evidence-Based Practice/standards; *Models, Theoretical; *Public Health Administration/methods/standards; Public Health; 1; Models; Theoretical; Scales; Professional Practice; Evidence-Based – Standards; Public Health Administration – Methods; Public Health Administration – Standards; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7X7GIDT7,journalArticle,2017,"Altalib, Hamada Hamid; Fenton, Brenda T.; Cheung, Kei-Hoi; Pugh, Mary Jo V.; Bates, Jonathan; Valente, Thomas W.; Kerns, Robert D.; Brandt, Cynthia A.",Care coordination in epilepsy: Measuring neurologists' connectivity using social network analysis.,Epilepsy & behavior : E&B,,1525-5069 1525-5050,10.1016/j.yebeh.2017.05.026,,"OBJECTIVE: The study sought to quantify coordination of epilepsy care, over time, between neurologists and other health care providers using social network analysis (SNA). METHODS: The Veterans Health Administration (VA) instituted an Epilepsy Center of Excellence (ECOE) model in 2008 to enhance care coordination between neurologists and other health care providers. Provider networks in the 16 VA ECOE facilities (hub sites) were compared to a subset of 33 VA facilities formally affiliated (consortium sites) and 14 unaffiliated VA facilities. The number of connections between neurologists and each provider (node degree) was measured by shared epilepsy patients and tallied to generate estimates at the facility level separately within and across facilities. Mixed models were used to compare change of facility-level node degree over time across the three facility types, adjusted for number of providers per facility. RESULTS: Over the time period 2000-2013, epilepsy care coordination both within and across facilities significantly increased. These increases were seen in all three types of facilities namely hub, consortium, and unaffiliated site, relatively equally. The increase in connectivity was more dramatic with providers across facilities compared to providers within the same facilities. CONCLUSION: Establishment of the ECOE hub and spoke model contributed to an increase in epilepsy care coordination both within and across facilities from 2000 to 2013, but there was substantial variation across different facilities. SNA is a tool that may help measure coordination of specialty care.",2017-08,13/11/2018 10:47,14/04/2020 08:34,,31-35,,,73,,Epilepsy Behav,,,,,,,,eng,Published by Elsevier Inc.,,,,,,PMID: 28605631,,,,Humans; United States; *Coordination of care; *Epilepsy; *Health services; *Social network analysis; *Social Networking; Epilepsy/*therapy; Health Personnel/*statistics & numerical data; Health Services/*statistics & numerical data; Neurologists/*statistics & numerical data; United States Department of Veterans Affairs; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HLYLL85C,journalArticle,2017,"Guise, Jeanne-Marie; Hansen, Matthew; Lambert, William; O'Brien, Kerth",The role of simulation in mixed-methods research: a framework & application to patient safety.,BMC health services research,,1472-6963 1472-6963,10.1186/s12913-017-2255-7,,"BACKGROUND: Research in patient safety is an important area of health services research and is a national priority. It is challenging to investigate rare occurrences, explore potential causes, and account for the complex, dynamic context of healthcare - yet all are required in patient safety research. Simulation technologies have become widely accepted as education and clinical tools, but have yet to become a standard tool for research. METHODS: We developed a framework for research that integrates accepted patient safety models with mixed-methods research approaches and describe the performance of the framework in a working example of a large National Institutes of Health (NIH)-funded R01 investigation. RESULTS: This worked example of a framework in action, identifies the strengths and limitations of qualitative and quantitative research approaches commonly used in health services research. Each approach builds essential layers of knowledge. We describe how the use of simulation ties these layers of knowledge together and adds new and unique dimensions of knowledge. CONCLUSIONS: A mixed-methods research approach that includes simulation provides a broad multi-dimensional approach to health services and patient safety research.",04/05/2017,13/11/2018 10:47,14/04/2020 08:34,,322,,1,17,,BMC Health Serv Res,,,,,,,,eng,,,,,,,PMID: 28472958 PMCID: PMC5418848,,,,Humans; Patient Safety; Simulation Training; Focus Groups; Child; *Patient Safety; *Emergency care; *Health services research; *Mixed methods; *National Institutes of Health; *Patient safety; *Patient simulation; *Pediatrics; *Qualitative research; *Research design; *Research Design; Delphi Technique; Health Services Research/*methods; Human; Health Services Research – Methods; Study Design; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XHTRYUT5,journalArticle,2017,"O'Donnell, Eloise; Atkinson, Jo-An; Freebairn, Louise; Rychetnik, Lucie",Participatory simulation modelling to inform public health policy and practice: Rethinking the evidence hierarchies.,Journal of public health policy,,1745-655X 0197-5897,10.1057/s41271-016-0061-9,,"Drawing on the long tradition of evidence-based medicine that aims to improve the efficiency and effectiveness of clinical practice, the field of public health has sought to apply 'hierarchies of evidence' to appraise and synthesise public health research. Various critiques of this approach led to the development of synthesis methods that include broader evidence typologies and more 'fit for purpose' privileging of methodological designs. While such adaptations offer great utility for evidence-informed public health policy and practice, this paper offers an alternative perspective on the synthesis of evidence that necessitates a yet more egalitarian approach. Dynamic simulation modelling is increasingly recognised as a valuable evidence synthesis tool to inform public health policy and programme planning for complex problems. The development of simulation models draws on and privileges a wide range of evidence typologies, thus challenging the traditional use of 'hierarchies of evidence' to support decisions on complex dynamic problems.",2017-05,13/11/2018 10:47,14/04/2020 08:34,,203-215,,2,38,,J Public Health Policy,,,,,,,,eng,,,,,,,PMID: 28386099,,,,*Health Policy; Humans; Health Policy; Randomized Controlled Trials as Topic; *Computer Simulation; Computer Simulation; Research Design; Public Health; *Public Health Practice; dynamic simulation modelling; evidence hierarchy; evidence synthesis; Evidence-Based Practice; health policy; participatory modelling; Policy Making; systems science; System dynamics; 1; Evidence-Based; Professional Practice; Study Design; Clinical Trials; 320,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, AG7V5CN2,journalArticle,2017,"Sau, Arkaprabha",A Simulation Study on Hypothetical Ebola Virus Transmission in India Using Spatiotemporal Epidemiological Modeler (STEM): A Way towards Precision Public Health.,Journal of environmental and public health,,1687-9813 1687-9805,10.1155/2017/7602301,,"Background. Precision public health is a state-of-the-art concept in public health research and its application in health care. Application of information technology in field of epidemiology paves the way to its transformation to digital epidemiology. A geospatial epidemiological model was simulated to estimate the spread of Ebola virus disease after a hypothetical outbreak in India. Methods. It was a simulation study based on SEIR (Susceptible-Exposed-Infectious-Recovered) compartmental model. Simulation was done in Spatiotemporal Epidemiological Modeler (STEM). Epidemiological profile of Ebola virus, that transmitted throughout the Sierra Leon in 2014-2016, was fitted into the SEIR deterministic compartment model designed for India. Result. Spatiotemporal distribution of EVD exposed, infectious, and recovered population at 4-month interval represented by different figures. It is estimated that if no intervention is taken to stop the spread, within 2 years, almost half of the country will be effected by EVD and cumulative number of exposed individuals, infectious persons, and deaths will be 106947760, 30651674, and 18391005, respectively. Conclusion. Precision public health may play the key role to achieve the health related targets in the Sustainable Development Goals. Policy makers, public health specialists, and data scientists need to put their hands together to make precision public health a reality.",2017,13/11/2018 10:47,14/04/2020 08:35,,7602301,,,2017,,J Environ Public Health,,,,,,,,eng,,,,,,,PMID: 28348606 PMCID: PMC5350287,,,,"Humans; *Computer Simulation; Computer Simulation; *Models, Theoretical; Public Health; *Disease Outbreaks; Ebolavirus/*physiology; Hemorrhagic Fever, Ebola/*epidemiology/*transmission/virology; India/epidemiology; Disease Outbreaks; India; 1; Human; Models; Theoretical; Ebola; Ebola – Epidemiology; Ebola – Transmission; Ebola Virus – Physiology; Hemorrhagic Fever; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QC82P75H,journalArticle,2017,"Hill, Andrew; Camacho, Oscar M.",A system dynamics modelling approach to assess the impact of launching a new nicotine product on population health outcomes.,Regulatory toxicology and pharmacology : RTP,,1096-0295 0273-2300,10.1016/j.yrtph.2017.03.012,,"In 2012 the US FDA suggested the use of mathematical models to assess the impact of releasing new nicotine or tobacco products on population health outcomes. A model based on system dynamics methodology was developed to project the potential effects of a new nicotine product at a population level. A model representing traditional smoking populations (never, current and former smokers) and calibrated using historical data was extended to a two-product model by including electronic cigarettes use statuses. Smoking mechanisms, such as product initiation, switching, transition to dual use, and cessation, were represented as flows between smoking statuses (stocks) and the potential effect of smoking renormalisation through a feedback system. Mortality over a 50-year period (2000-2050) was the health outcome of interest, and was compared between two scenarios, with and without e-cigarettes being introduced. The results suggest that by 2050, smoking prevalence in adults was 12.4% in the core model and 9.7% (including dual users) in the counterfactual. Smoking-related mortality was 8.4% and 8.1%, respectively. The results suggested an overall beneficial effect from launching e-cigarettes and that system dynamics could be a useful approach to assess the potential population health effects of nicotine products when epidemiological data are not available.",2017-06,13/11/2018 10:47,14/04/2020 08:34,,265-278,,,86,,Regul Toxicol Pharmacol,,,,,,,,eng,Copyright (c) 2017 The Authors. Published by Elsevier Inc. All rights reserved.,,,,,,PMID: 28342844,,,,"Humans; *Models, Theoretical; Modelling; *Forecasting; Cigarette; e-cigarette; Electronic Nicotine Delivery Systems; Harm Reduction; Nicotine; Nicotine/*adverse effects; Population modelling; Smoking Cessation; Smoking/*mortality; System dynamics; Tobacco; Tobacco Products/*adverse effects; system dynamics; 1; 220",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UX89F2UZ,journalArticle,2017,"Lutgendorf, Monica A.; Spalding, Carmen; Drake, Elizabeth; Spence, Dennis; Heaton, Jason O.; Morocco, Kristina V.",Multidisciplinary In Situ Simulation-Based Training as a Postpartum Hemorrhage Quality Improvement Project.,Military medicine,,1930-613X 0026-4075,10.7205/MILMED-D-16-00030,,"BACKGROUND: Postpartum hemorrhage is a common obstetric emergency affecting 3 to 5% of deliveries, with significant maternal morbidity and mortality. Effective management of postpartum hemorrhage requires strong teamwork and collaboration. We completed a multidisciplinary in situ postpartum hemorrhage simulation training exercise with structured team debriefing to evaluate hospital protocols, team performance, operational readiness, and real-time identification of system improvements. Our objective was to assess participant comfort with managing obstetric hemorrhage following our multidisciplinary in situ simulation training exercise. METHODS: This was a quality improvement project that utilized a comprehensive multidisciplinary in situ postpartum hemorrhage simulation exercise. Participants from the Departments of Obstetrics and Gynecology, Anesthesia, Nursing, Pediatrics, and Transfusion Services completed the training exercise in 16 scenarios run over 2 days. The intervention was a high fidelity, multidisciplinary in situ simulation training to evaluate hospital protocols, team performance, operational readiness, and system improvements. Structured debriefing was conducted with the participants to discuss communication and team functioning. Our main outcome measure was participant self-reported comfort levels for managing postpartum hemorrhage before and after simulation training. A",2017-03,13/11/2018 10:47,14/04/2020 08:34,,e1762-e1766,,3,182,,Mil Med,,,,,,,,eng,Reprint & Copyright (c) 2017 Association of Military Surgeons of the U.S.,,,,,,PMID: 28290956,,,,Humans; Female; *Patient Simulation; Patient Safety; Interprofessional Relations; Pregnancy; Quality Improvement; Anesthetists/statistics & numerical data; Blood Banks/methods/standards/statistics & numerical data; Blood Transfusion/methods/standards/statistics & numerical data; Clinical Competence/*standards/statistics & numerical data; Emergency Medical Technicians/statistics & numerical data; Health Personnel/*standards/statistics & numerical data; Interdisciplinary Communication; Midwifery/manpower/statistics & numerical data; Obstetric Labor Complications/therapy; Obstetric Nursing/manpower/statistics & numerical data; Obstetrics/manpower/statistics & numerical data; Patient Care Team/standards/statistics & numerical data; Postpartum Hemorrhage/*therapy; Program Evaluation/methods/statistics & numerical data; Teaching/*standards/statistics & numerical data; Health Personnel; Patient Simulation; Blood Banks – Methods; Blood Banks – Standards; Blood Banks – Statistics and Numerical Data; Blood Transfusion – Methods; Blood Transfusion – Statistics and Numerical Data; Blood Trs; Clinical Competence – Standards; Clinical Competence – Statistics and Numerical Data; Emergency Medical Technicians – Statistics and Numerical Data; Health Personnel – Statistics and Numerical Data; Labor Complications – Therapy; Midwifery – Manpower; Midwifery – Statistics and Numerical Data; Multidisciplinary Care Team – Standards; Multidisciplinary Care Team – Statistics and Numerical Data; Obstetric Nursing – Manpower; Obstetrics – Manpower; Obstetrics – Statistics and Numerical Data; Postpartum Hemorrhage – Therapy; Program Evaluation – Methods; Program Evaluation – Statistics and Numerical Data; Teaching – Standards; Teaching – Statistics and Numerical Data; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, L3H2NY6S,journalArticle,2017,"Al-Jumaili, Ali Azeez; Doucette, William R.",Comprehensive Literature Review of Factors Influencing Medication Safety in Nursing Homes: Using a Systems Model.,Journal of the American Medical Directors Association,,1538-9375 1525-8610,10.1016/j.jamda.2016.12.069,,"OBJECTIVES: The objectives of this review were to identify the work system factors influencing medication safety measures [adverse drug events (ADEs), adverse drug reactions, or medication errors (MEs)], to determine the incidence of ADEs, and describe the most common ADEs in nursing homes (NHs). METHODS: A comprehensive literature review was conducted using PubMed and CINAHL to identify studies investigating factors that influence ADEs, adverse drug reactions, and MEs in NHs and skilled nursing facilities. An initial search identified related studies over 3 decades (1985-2016). Studies were classified according to Systems Engineering Initiative for Patient Safety model factors. RESULTS: Sixty studies were included in this review, which identifies 5 categories of work system factors affecting medication safety in NHs: persons (resident and staff), organization, tools and technology, tasks, and environment. The personal characteristics of NH residents included age, number and types of scheduled medications, and number and types of comorbidities. In addition, inadequate nursing staff medication knowledge and training are usually associated with administration MEs. Organizational factors include interprofessional collaboration, physician and pharmacist accessibility, and staff/resident ratio. A high staff number plays an essential role in preventing MEs and fracture incidents. The technology (barcode medication system) and tools (ME-reporting systems, ADE trigger tool, and potentially inappropriate medication criteria) can enhance the detection of MEs and ADEs. Workload and time pressure negatively impact NH staff task performance. Use of an ADE trigger tool by healthcare providers enhanced the ability to identify ADEs more than 50-fold over 6 months. Several environmental characteristics such as staff distraction and interruption negatively influence medication safety in NHs. The incidence rates of ADEs in NHs ranged from 1.89 to 10.8 per 100 resident-months. The most common ADEs were bleeding, thromboembolic events, hypoglycemia, falls, and constipation. CONCLUSIONS: The Systems Engineering Initiative for Patient Safety model is a useful framework for investigating the factors contributing to ADEs. Multiple work-system factors affect the medication safety of NH residents. A comprehensive study is needed to quantify the influence of various work-system factors on ADEs in NHs.",01/06/2017,13/11/2018 10:47,14/04/2020 08:34,,470-488,,6,18,,J Am Med Dir Assoc,,,,,,,,eng,Copyright (c) 2016 AMDA - The Society for Post-Acute and Long-Term Care Medicine. Published by Elsevier Inc. All rights reserved.,,,,,,PMID: 28242191,,,,"Humans; Drug-Related Side Effects and Adverse Reactions/*prevention & control; Models, Theoretical; Time Factors; adverse drug events; Medication Errors/*prevention & control; Medication safety; nursing homes; Nursing Homes/*organization & administration; SEIPS model; 1; Human; Adverse Drug Event – Evaluation; CINAHL Database; Medication Errors – Evaluation; Nursing Homes; Patient Safety – Evaluation; PubMed; Systematic Review; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QSPMWESM,journalArticle,2017,"McDonald, Elizabeth L.; Bailie, Ross S.; Morris, Peter S.",Participatory systems approach to health improvement in Australian Aboriginal children.,Health promotion international,,1460-2245 0957-4824,10.1093/heapro/dau003,,"Summary: The factors underlying poor child health in remote Australian Indigenous (Aboriginal and Torres Strait Islander) communities are complex. There is a lack of consistent and reliable information that allows: (i) the identification of priorities or areas of particular need at household and community levels; (ii) monitoring progress over time; and (iii) the assessment of the impact of interventions. This paper describes the process and methods used to identify the factors that underlie high rates of poor child health in remote Aboriginal communities in the Northern Territory (NT). This work has led to the development of indicators and tools suitable for use within a continuous quality improvement programme. Indigenous and non-Indigenous individuals from a range of disciplines and backgrounds participated in study activities. This allowed for a range of perspectives, including scientific, lay and Aboriginal perspectives, to be accommodated and reflected in study outcomes and outputs. Study participants identified a wide range of physical and social factors that they believe underlies poor child health in remote Aboriginal community contexts in the NT. The approach taken in this study provides some confidence that the indicators developed will be seen as meaningful and appropriate by the residents of remote communities and key stakeholders. Two tools have been developed and are now in use in the practice setting. One assesses social determinants of health at the community level, for example water supply, food supply. The second applies to individual households and assesses the social and environmental indicators that are recognized as placing children at greater risk of poor health and development outcomes.",01/02/2017,13/11/2018 10:47,14/04/2020 08:34,,62-72,,1,32,,Health Promot Int,,,,,,,,eng,,,,,,,PMID: 28180314,,,,Humans; Socioeconomic Factors; *Oceanic Ancestry Group; Community-Based Participatory Research; Child; Australia; *Child Health; Health Promotion/methods; Health Status Disparities; Needs Assessment; Models; Theoretical; Aboriginal Australians – Australia; Child Health – Australia; Clinical Indicators; Conceptual Framework; Health Promotion – In Infancy and Childhood – Australia; Home Environment; Poverty Areas – Australia; Rural Health – Australia; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, W3AENGRH,journalArticle,2017,"Alexander, Gina K.; Canclini, Sharon B.; Fripp, Jon; Fripp, William",Waterborne Disease Case Investigation: Public Health Nursing Simulation.,The Journal of nursing education,,1938-2421 0148-4834,10.3928/01484834-20161219-08,,"BACKGROUND: The lack of safe drinking water is a significant public health threat worldwide. Registered nurses assess the physical environment, including the quality of the water supply, and apply environmental health knowledge to reduce environmental exposures. The purpose of this research brief is to describe a waterborne disease simulation for students enrolled in a public health nursing (PHN) course. METHOD: A total of 157 undergraduate students completed the simulation in teams, using the SBAR (Situation-Background-Assessment-Recommendation) reporting tool. Simulation evaluation consisted of content analysis of the SBAR tools and debriefing notes. RESULTS: Student teams completed the simulation and articulated the implications for PHN practice. Student teams discussed assessment findings and primarily recommended four nursing interventions: health teaching focused on water, sanitation, and hygiene; community organizing; collaboration; and advocacy to ensure a safe water supply. CONCLUSION: With advanced planning and collaboration with partners, waterborne disease simulation may enhance PHN education. [J Nurs Educ. 2017;56(1):39-42.].",01/01/2017,13/11/2018 10:47,14/04/2020 08:34,,39-42,,1,56,,J Nurs Educ,,,,,,,,eng,"Copyright 2017, SLACK Incorporated.",,,,,,PMID: 28118474,,,,"Humans; Program Evaluation; United States; Nursing Education Research; Curriculum; Risk Assessment; Communication; Education, Nursing, Baccalaureate/*methods; Environmental Health/*education; Public Health Nursing/*education; Waterborne Diseases/*nursing; Students; Nursing; Human; Content Analysis; Baccalaureate; Simulations; Funding Source; Cross Sectional Studies; Bacterial Contamination – Etiology; Case Management; Community Health Nursing – Education; Environmental Exposure – Prevention and Control; Environmental Monitoring – Education; Nursing – United States; Schools; Water Supply; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XK2A6HR9,journalArticle,2017,"Bryant, Maria; Burton, Wendy; Cundill, Bonnie; Farrin, Amanda J.; Nixon, Jane; Stevens, June; Roberts, Kim; Foy, Robbie; Rutter, Harry; Hartley, Suzanne; Tubeuf, Sandy; Collinson, Michelle; Brown, Julia","Effectiveness of an implementation optimisation intervention aimed at increasing parent engagement in HENRY, a childhood obesity prevention programme - the Optimising Family Engagement in HENRY (OFTEN) trial: study protocol for a randomised controlled trial.",Trials,,1745-6215 1745-6215,10.1186/s13063-016-1732-3,,"BACKGROUND: Family-based interventions to prevent childhood obesity depend upon parents' taking action to improve diet and other lifestyle behaviours in their families. Programmes that attract and retain high numbers of parents provide an enhanced opportunity to improve public health and are also likely to be more cost-effective than those that do not. We have developed a theory-informed optimisation intervention to promote parent engagement within an existing childhood obesity prevention group programme, HENRY (Health Exercise Nutrition for the Really Young). Here, we describe a proposal to evaluate the effectiveness of this optimisation intervention in regard to the engagement of parents and cost-effectiveness. METHODS/DESIGN: The Optimising Family Engagement in HENRY (OFTEN) trial is a cluster randomised controlled trial being conducted across 24 local authorities (approximately 144 children's centres) which currently deliver HENRY programmes. The primary outcome will be parental enrolment and attendance at the HENRY programme, assessed using routinely collected process data. Cost-effectiveness will be presented in terms of primary outcomes using acceptability curves and through eliciting the willingness to pay for the optimisation from HENRY commissioners. Secondary outcomes include the longitudinal impact of the optimisation, parent-reported infant intake of fruits and vegetables (as a proxy to compliance) and other parent-reported family habits and lifestyle. DISCUSSION: This innovative trial will provide evidence on the implementation of a theory-informed optimisation intervention to promote parent engagement in HENRY, a community-based childhood obesity prevention programme. The findings will be generalisable to other interventions delivered to parents in other community-based environments. This research meets the expressed needs of commissioners, children's centres and parents to optimise the potential impact that HENRY has on obesity prevention. A subsequent cluster randomised controlled pilot trial is planned to determine the practicality of undertaking a definitive trial to robustly evaluate the effectiveness and cost-effectiveness of the optimised intervention on childhood obesity prevention. TRIAL REGISTRATION: ClinicalTrials.gov identifier: NCT02675699 . Registered on 4 February 2016.",24/01/2017,13/11/2018 10:47,14/04/2020 08:34,,40,,1,18,,Trials,,,,,,,,eng,,,,,,,PMID: 28115006 PMCID: PMC5260000,,,,Humans; Cost-Benefit Analysis; Treatment Outcome; Health Care Costs; Risk Factors; *Trial; Research Design; Time Factors; United Kingdom; Behavior; *Childhood obesity; *Community Health Services/economics; *Engagement; *Implementation; *Parent; *Recruitment; Exercise; Family Therapy/economics/*methods; Habits; Healthy Diet; Parents/*psychology; Pediatric Obesity/diagnosis/economics/*prevention & control/psychology; Preventive Health Services/economics/*methods; Risk Reduction Behavior; 1; Human; Randomized Controlled Trials; Comparative Studies; Cost Benefit Analysis; Evaluation Research; Multicenter Studies; Validation Studies; Study Design; Community Health Services – Economics; Family Therapy – Economics; Family Therapy – Methods; Parents – Psychosocial Factors; Pediatric Obesity – Diagnosis; Pediatric Obesity – Economics; Pediatric Obesity – Prevention and Control; Pediatric Obesity – Psychosocial Factors; Preventive Health Care – Economics; Preventive Health Care – Methods; Treatment Outcomes; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RNGSVF6Z,journalArticle,2017,"Crowe, Sonya; Brown, Katherine; Tregay, Jenifer; Wray, Jo; Knowles, Rachel; Ridout, Deborah A.; Bull, Catherine; Utley, Martin",Combining qualitative and quantitative operational research methods to inform quality improvement in pathways that span multiple settings.,BMJ quality & safety,,2044-5423 2044-5415,10.1136/bmjqs-2016-005636,,"BACKGROUND: Improving integration and continuity of care across sectors within resource constraints is a priority in many health systems. Qualitative operational research methods of problem structuring have been used to address quality improvement in services involving multiple sectors but not in combination with quantitative operational research methods that enable targeting of interventions according to patient risk. We aimed to combine these methods to augment and inform an improvement initiative concerning infants with congenital heart disease (CHD) whose complex care pathway spans multiple sectors. METHODS: Soft systems methodology was used to consider systematically changes to services from the perspectives of community, primary, secondary and tertiary care professionals and a patient group, incorporating relevant evidence. Classification and regression tree (CART) analysis of national audit datasets was conducted along with data visualisation designed to inform service improvement within the context of limited resources. RESULTS: A 'Rich Picture' was developed capturing the main features of services for infants with CHD pertinent to service improvement. This was used, along with a graphical summary of the CART analysis, to guide discussions about targeting interventions at specific patient risk groups. Agreement was reached across representatives of relevant health professions and patients on a coherent set of targeted recommendations for quality improvement. These fed into national decisions about service provision and commissioning. CONCLUSIONS: When tackling complex problems in service provision across multiple settings, it is important to acknowledge and work with multiple perspectives systematically and to consider targeting service improvements in response to confined resources. Our research demonstrates that applying a combination of qualitative and quantitative operational research methods is one approach to doing so that warrants further consideration.",2017-08,13/11/2018 10:47,14/04/2020 08:34,,641-652,,8,26,,BMJ Qual Saf,,,,,,,,eng,Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.,,,,,,PMID: 28062603 PMCID: PMC5537516,,,,"Humans; Program Evaluation; Female; Male; Quality Improvement; Infant; Quality Improvement/*organization & administration; United Kingdom; *Research Design; *Operations Research; Continuity of Patient Care; Healthcare quality improvement; Heart Defects, Congenital/therapy; Implementation science; Patient Care Management/organization & administration; Quality improvement methodologies; Systems Integration; 1; Human; Models; Theoretical; Funding Source; Seminars and Workshops; Statistical; Adverse Health Care Event – Risk Factors; Community Health Nursing – United Kingdom; Congenital; Data Analysis; Heart Defects; Multimethod Studies – United Kingdom; Nursing Protocols; Patient Care – In Infancy and Childhood; Regression; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, V4N6I5DU,journalArticle,2017,"Chughtai, Saad; Blanchet, Karl",Systems thinking in public health: a bibliographic contribution to a meta-narrative review.,Health policy and planning,,1460-2237 0268-1080,10.1093/heapol/czw159,,"Background: Research across the formal, natural and social sciences has greatly expanded our knowledge about complex systems in recent decades, informing a broadly inclusive, cross-disciplinary conceptual framework referred to as Systems Thinking (ST). Its use in public health is rapidly increasing, although there remains a poor understanding of how these ideas have been imported, adapted and elaborated by public health research networks worldwide. Method: This review employed a mixed methods approach to narrate the development of ST in public health. Tabulated results from a literature search of the Web of Science Core Collection database were used to perform a bibliometric analysis and literature review. Annual publication counts and citation scores were used to analyse trends and identify popular and potential 'landmark' publications. Citation network and co-authorship network diagrams were analysed to identify groups of articles and researchers in various network roles. Results: Our search string related to 763 publications. Filtering excluded 208 publications while citation tracing identified 2 texts. The final 557 publications were analysed, revealing a near-exponential growth in literature over recent years. Half of all articles were published after 2010 with almost a fifth (17.8%) published in 2014. Bibliographic analysis identified five distinct citation and co-authorship groups homophilous by common geography, research focus, inspiration or institutional affiliation. As a loosely related set of sciences, many public health researchers have developed different aspects of ST based on their underlying perspective. Early studies were inspired by Management-related literature, while later groups adopted a broadly inclusive understanding which incorporated related Systems sciences and approaches. Conclusion: ST is an increasingly popular subject of discussion within public health although its understanding and approaches remain unclear. Briefly tracing the introduction and development of these ideas and author groups in public health literature may provide clarity and opportunities for further learning, research and development.",01/05/2017,13/11/2018 10:47,14/04/2020 08:34,,585-594,,4,32,,Health Policy Plan,,,,,,,,eng,"(c) The Author 2017. Published by Oxford University Press in association with The London School of Hygiene and Tropical Medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com",,,,,,PMID: 28062516,,,,Humans; Health Services Research; *Public Health; *Systems Analysis; Systems Analysis; public health; systems thinking; Public Health; Health systems; *Bibliometrics; Global Health; health systems research; social sciences; Human; Systematic Review; Bibliometrics; World Health; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RF76SUR9,journalArticle,2016,"Forestier-Zhang, Lydia; Watts, Laura; Turner, Alison; Teare, Harriet; Kaye, Jane; Barrett, Joe; Cooper, Cyrus; Eastell, Richard; Wordsworth, Paul; Javaid, Muhammad K.; Pinedo-Villanueva, Rafael","Health-related quality of life and a cost-utility simulation of adults in the UK with osteogenesis imperfecta, X-linked hypophosphatemia and fibrous dysplasia.",Orphanet journal of rare diseases,,1750-1172 1750-1172,10.1186/s13023-016-0538-4,,"BACKGROUND: Health-related quality of life of adults with osteogenesis imperfecta (OI), fibrous dysplasia (FD) and X-linked hypophosphatemia (XLH) remains poorly described. The aim of this study was to describe the HRQoL of adults with osteogenesis imperfecta, fibrous dysplasia and X-linked hypophophataemia and perform a cost-utility simulation to calculate the maximum cost that a health care system would be willing to pay for a hypothetical treatment of a rare bone disease. RESULTS: Participants completed the EQ-5D-5 L questionnaire between September 2014 and March 2016. For the economic simulation, we considered a hypothetical treatment that would be applied to OI participants in the lower tertile of the health utility score. A total of 109 study participants fully completed the EQ-5D-5 L questionnaire (response rate 63%). Pain/discomfort was the most problematic domain for participants with all three diseases (FD 31%, XLH 25%, OI 16%). The economic simulation identified an expected treatment impact of +2.5 QALYs gained per person during the 10-year period, which led to a willing to pay of pound14,355 annually for a health care system willing to pay up to pound50,000 for each additional QALY gained by an intervention. CONCLUSIONS: This is the first study to quantitatively measure and compare the HRQoL of adults with OI, FD and XLH and the first to use such data to conduct an economic simulation leading to healthcare system willingness-to-pay estimates for treatment of musculoskeletal rare diseases at various cost-effectiveness thresholds.",28/11/2016,13/11/2018 10:47,14/04/2020 08:34,,160,,1,11,,Orphanet J Rare Dis,,,,,,,,eng,,,,,,,PMID: 27894323 PMCID: PMC5126812,,,,"Humans; Adult; Female; Male; Middle Aged; Young Adult; Aged; Quality of Life; Adolescent; United Kingdom; *Economic evaluation; *Fibrous dysplasia; *McCune Albright syndrome; *Osteogenesis imperfecta; *Quality of life; *Quality of Life; *X-linked hypophosphatemia; Cross-Sectional Studies; Familial Hypophosphatemic Rickets/*physiopathology; Fibrous Dysplasia, Polyostotic/*physiopathology; Osteogenesis Imperfecta/*physiopathology; Human; Comparative Studies; Middle Age; Scales; Questionnaires; Funding Source; Evaluation Research; Multicenter Studies; Validation Studies; Adolescence; Cross Sectional Studies; Fibrous Dysplasia; Osteogenesis Imperfecta – Physiopathology; Polyostotic – Physiopathology; 00; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HC9JL8IA,journalArticle,2016,"Kearney, Sarah; Leung, Loksee; Joyce, Andrew; Ollis, Debbie; Green, Celia",Applying systems theory to the evaluation of a whole school approach to violence prevention.,Health promotion journal of Australia : official journal of Australian Association of Health Promotion Professionals,,1036-1073 1036-1073,10.1071/HE16046,,"Issue addressed Our Watch led a complex 12-month evaluation of a whole school approach to Respectful Relationships Education (RRE) implemented in 19 schools. RRE is an emerging field aimed at preventing gender-based violence. This paper will illustrate how from an implementation science perspective, the evaluation was a critical element in the change process at both a school and policy level. Methods Using several conceptual approaches from systems science, the evaluation sought to examine how the multiple systems layers - student, teacher, school, community and government - interacted and influenced each other. A distinguishing feature of the evaluation included 'feedback loops'; that is, evaluation data was provided to participants as it became available. Evaluation tools included a combination of standardised surveys (with pre- and post-intervention data provided to schools via individualised reports), reflection tools, regular reflection interviews and summative focus groups. Results Data was shared during implementation with project staff, department staff and schools to support continuous improvement at these multiple systems levels. In complex settings, implementation can vary according to context; and the impact of evaluation processes, tools and findings differed across the schools. Interviews and focus groups conducted at the end of the project illustrated which of these methods were instrumental in motivating change and engaging stakeholders at both a school and departmental level and why. Conclusion The evaluation methods were a critical component of the pilot's approach, helping to shape implementation through data feedback loops and reflective practice for ongoing, responsive and continuous improvement. Future health promotion research on complex interventions needs to examine how the evaluation itself is influencing implementation. So what? The pilot has demonstrated that the evaluation, including feedback loops to inform project activity, were an asset to implementation. This has implications for other health promotion activities, where evaluation tools could be utilised to enhance, rather than simply measure, an intervention. The findings are relevant to a range of health promotion research activities because they demonstrate the importance of meta-evaluation techniques that seek to understand how the evaluation itself was influencing implementation and outcomes.",2016-02,13/11/2018 10:47,14/04/2020 08:34,,230-235,,3,27,,Health Promot J Austr,,,,,,,,eng,,,,,,,PMID: 27719735,,,,Humans; Health Promotion; Program Evaluation; Surveys and Questionnaires; Health Services Research; Community-Based Participatory Research; Systems Theory; *Health Promotion; *Systems Theory; Organizational Objectives; Organizational Innovation; Violence/*prevention & control; *Schools; Feedback; Victoria; Human; Organizational Change; Schools; Violence – Prevention and Control; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5933Z439,journalArticle,2017,"Banbury, Annie; Chamberlain, Daniel; Nancarrow, Susan; Dart, Jared; Gray, Len; Parkinson, Lynne",Can videoconferencing affect older people's engagement and perception of their social support in long-term conditions management: a social network analysis from the Telehealth Literacy Project.,Health & social care in the community,,1365-2524 0966-0410,10.1111/hsc.12382,,"Social support is a key component in managing long-term conditions. As people age in their homes, there is a greater risk of social isolation, which can be ameliorated by informal support networks. This study examined the relationship between changes in social support networks for older people living in a regional area following weekly videoconference groups delivered to the home. Between February and June 2014, we delivered 44 weekly group meetings via videoconference to participants in a regional town in Australia. The meetings provided participants with education and an opportunity to discuss health issues and connect with others in similar circumstances. An uncontrolled, pre-post-test methodology was employed. A social network tool was completed by 45 (87%) participants either pre- or post-intervention, of which 24 (46%) participants completed the tool pre- and post-intervention. In addition, 14 semi-structured interviews and 4 focus groups were conducted. Following the intervention, participants identified increased membership of their social networks, although they did not identify individuals from the weekly videoconference groups. The most important social support networks remained the same pre- and post-intervention namely, health professionals, close family and partners. However, post-intervention participants identified friends and wider family as more important to managing their chronic condition compared to pre-intervention. Participants derived social support, in particular, companionship, emotional and informational support as well as feeling more engaged with life, from the weekly videoconference meetings. Videoconference education groups delivered into the home can provide social support and enhance self-management for older people with chronic conditions. They provide the opportunity to develop a virtual social support network containing new and diverse social connections.",2017-05,13/11/2018 10:47,14/04/2020 08:34,,938-950,,3,25,,Health Soc Care Community,,,,,,,,eng,(c) 2016 John Wiley & Sons Ltd.,,,,,,PMID: 27573127,,,,"Humans; Surveys and Questionnaires; Female; Male; Aged; Focus Groups; Aged, 80 and over; Chronic Disease; *Chronic conditions; *long-term conditions; *older people; *social isolation; *social support; *Social Support; *Telehealth; *Videoconferencing; Health Knowledge, Attitudes, Practice; Long-Term Care; Patients/*psychology; Social Isolation; 1; Human; Pretest-Posttest Design; Descriptive Research; Self Care; Chronic Disease – Therapy – In Old Age; Coding; Family Relations; Hardiness; Multimethod Studies; New South Wales; Perception; Psychosocial – In Old Age; Questionnaires; Semi-Structured Interview; Support; Telehealth – In Old Age; Thematic Analysis; Videoconferencing – Utilization – In Old Age; Social Networks analysis; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 95QXVQT8,journalArticle,2016,"McCullough, J. Mac; Eisen-Cohen, Eileen; Salas, S. Bianca",Partnership capacity for community health improvement plan implementation: findings from a social network analysis.,BMC public health,,1471-2458 1471-2458,10.1186/s12889-016-3194-7,,"BACKGROUND: Many health departments collaborate with community organizations on community health improvement processes. While a number of resources exist to plan and implement a community health improvement plan (CHIP), little empirical evidence exists on how to leverage and expand partnerships when implementing a CHIP. The purpose of this study was to identify characteristics of the network involved in implementing the CHIP in one large community. The aims of this analysis are to: 1) identify essential network partners (and thereby highlight potential network gaps), 2) gauge current levels of partner involvement, 3) understand and effectively leverage network resources, and 4) enable a data-driven approach for future collaborative network improvements. METHODS: We collected primary data via survey from n = 41 organizations involved in the Health Improvement Partnership of Maricopa County (HIPMC), in Arizona. Using the previously validated Program to Analyze, Record, and Track Networks to Enhance Relationships (PARTNER) tool, organizations provided information on existing ties with other coalition members, including frequency and depth of partnership and eight categories of perceived value/trust of each current partner organization. RESULTS: The coalition's overall network had a density score of 30 %, degree centralization score of 73 %, and trust score of 81 %. Network maps are presented to identify existing relationships between HIPMC members according to partnership frequency and intensity, duration of involvement in the coalition, and self-reported contributions to the coalition. Overall, number of ties and other partnership measures were positively correlated with an organization's perceived value and trustworthiness as rated by other coalition members. CONCLUSIONS: Our study presents a novel use of social network analysis methods to evaluate the coalition of organizations involved in implementing a CHIP in an urban community. The large coalition had relatively low network density but high degree centralization-meaning key organizations link organizations otherwise not tightly partnering. Coalition members rated each other highly on trust, a positive sign for future partnership development efforts. Examination of network maps reveal key organizations that can be targeted for future partnership facilitation and expansion. Future network data collection will enable exploration of longitudinal trends and exploration of network characteristics versus health behavior, status, and outcome changes.",13/07/2016,13/11/2018 10:47,14/04/2020 08:34,,566,,,16,,BMC Public Health,,,,,,,,eng,,,,,,,PMID: 27411474 PMCID: PMC4944444,,,,Humans; Surveys and Questionnaires; *Social network analysis; *Cooperative Behavior; *Social Support; *Community health improvement plan; *Local health department; Arizona; Community Health Planning/*organization & administration; Community Health Services/*organization & administration; Health Plan Implementation/*methods; Cooperative Behavior; Human; Support; Community Health Services – Administration; Health and Welfare Planning – Administration; Health and Welfare Planning – Methods; Psychosocial; 00; ******To read; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, W76CSKL9,journalArticle,2016,"Minkovitz, Cynthia S.; Grason, Holly; Ruderman, Marjory; Casella, James F.",Newborn Screening Programs and Sickle Cell Disease: A Public Health Services and Systems Approach.,American journal of preventive medicine,,1873-2607 0749-3797,10.1016/j.amepre.2016.02.019,,"INTRODUCTION: Despite universal newborn screening (NBS), children in the U.S. continue to experience morbidity and mortality from sickle cell disease and related causes. Recognizing that assessments of public health services and systems can improve public health system performance and ultimately health outcomes, this study examined variations in NBS program activities for sickle cell disease. METHODS: A mixed methods study included (1) a 2009 survey of NBS programs based on ten essential public health services (N=39 states with ten or more sickle cell births over a 3-year period) and (2) key informant interviews in 2011 with 13 states that had sufficient Phase 1 survey scores, black births, and variability in state legislation and geography. Key informants were from 13 NBS programs, 22 sickle cell treatment centers, and ten advocacy organizations. Analyses were conducted in 2009-2014. RESULTS: Considerable variability exists across states in program activities and roles. More programs reported activities oriented to care of individuals-ensuring access to services, coordination, and provider education; fewer reported planning and analysis activities oriented to statewide policy development and system change. Numbers of activities were not related to the number of affected births. In-depth interviews identified opportunities to enhance activities that support statewide comprehensive systems of care. CONCLUSIONS: NBS programs perform important public health roles that complement and enhance clinical services. Nationwide efforts are needed to enable NBS programs to strengthen population-based functions that are essential to ensuring quality of care for the entire population of children and families affected by sickle cell disease.",2016-07,13/11/2018 10:47,14/04/2020 08:34,,S39-47,,1 Suppl 1,51,,Am J Prev Med,,,,,,,,eng,Copyright (c) 2016 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.,,,,,,PMID: 27320464 PMCID: PMC4916337,,,,"Humans; United States; Female; *Public Health; *Systems Analysis; Systems Analysis; Public Health; Infant; *Neonatal Screening; Anemia, Sickle Cell/*mortality; Infant, Newborn; Interviews as Topic; Human; Funding Source; Interviews; Newborn; Anemia; Neonatal Assessment; Sickle Cell – Mortality; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, N6XWVQG6,journalArticle,2016,"Li, Yan; Lawley, Mark A.; Siscovick, David S.; Zhang, Donglan; Pagan, Jose A.",Agent-Based Modeling of Chronic Diseases: A Narrative Review and Future Research Directions.,Preventing chronic disease,,1545-1151 1545-1151,10.5888/pcd13.150561,,"The United States is experiencing an epidemic of chronic disease. As the US population ages, health care providers and policy makers urgently need decision models that provide systematic, credible prediction regarding the prevention and treatment of chronic diseases to improve population health management and medical decision-making. Agent-based modeling is a promising systems science approach that can model complex interactions and processes related to chronic health conditions, such as adaptive behaviors, feedback loops, and contextual effects. This article introduces agent-based modeling by providing a narrative review of agent-based models of chronic disease and identifying the characteristics of various chronic health conditions that must be taken into account to build effective clinical- and policy-relevant models. We also identify barriers to adopting agent-based models to study chronic diseases. Finally, we discuss future research directions of agent-based modeling applied to problems related to specific chronic health conditions.",26/05/2016,13/11/2018 10:47,14/04/2020 08:34,,E69,,,13,,Prev Chronic Dis,,,,,,,,eng,,,,,,,PMID: 27236380 PMCID: PMC4885681,,,,"Humans; United States; *Systems Analysis; Systems Analysis; Comorbidity; United States/epidemiology; *Models, Theoretical; Chronic Disease/*epidemiology/*prevention & control; Research/*trends; 1; Human; Chronic Disease – Prevention and Control; Comparative Studies; Models; Theoretical; Evaluation Research; Multicenter Studies; Validation Studies; Systematic Review; Chronic Disease – Epidemiology; Research – Trends; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7N78E5CJ,journalArticle,2016,"Ngalesoni, Frida N.; Ruhago, George M.; Mori, Amani T.; Robberstad, Bjarne; Norheim, Ole F.",Cost-effectiveness of medical primary prevention strategies to reduce absolute risk of cardiovascular disease in Tanzania: a Markov modelling study.,BMC health services research,,1472-6963 1472-6963,10.1186/s12913-016-1409-3,,"BACKGROUND: Cardiovascular disease (CVD) is a growing cause of mortality and morbidity in Tanzania, but contextualized evidence on cost-effective medical strategies to prevent it is scarce. We aim to perform a cost-effectiveness analysis of medical interventions for primary prevention of CVD using the World Health Organization's (WHO) absolute risk approach for four risk levels. METHODS: The cost-effectiveness analysis was performed from a societal perspective using two Markov decision models: CVD risk without diabetes and CVD risk with diabetes. Primary provider and patient costs were estimated using the ingredients approach and step-down methodologies. Epidemiological data and efficacy inputs were derived from systematic reviews and meta-analyses. We used disability- adjusted life years (DALYs) averted as the outcome measure. Sensitivity analyses were conducted to evaluate the robustness of the model results. RESULTS: For CVD low-risk patients without diabetes, medical management is not cost-effective unless willingness to pay (WTP) is higher than US$1327 per DALY averted. For moderate-risk patients, WTP must exceed US$164 per DALY before a combination of angiotensin converting enzyme inhibitor (ACEI) and diuretic (Diu) becomes cost-effective, while for high-risk and very high-risk patients the thresholds are US$349 (ACEI, calcium channel blocker (CCB) and Diu) and US$498 per DALY (ACEI, CCB, Diu and Aspirin (ASA)) respectively. For patients with CVD risk with diabetes, a combination of sulfonylureas (Sulf), ACEI and CCB for low and moderate risk (incremental cost-effectiveness ratio (ICER) US$608 and US$115 per DALY respectively), is the most cost-effective, while adding biguanide (Big) to this combination yielded the most favourable ICERs of US$309 and US$350 per DALY for high and very high risk respectively. For the latter, ASA is also part of the combination. CONCLUSIONS: Medical preventive cardiology is very cost-effective for all risk levels except low CVD risk. Budget impact analyses and distributional concerns should be considered further to assess governments' ability and to whom these benefits will accrue.",17/05/2016,13/11/2018 10:47,14/04/2020 08:35,,185,,,16,,BMC Health Serv Res,,,,,,,,eng,,,,,,,PMID: 27184802 PMCID: PMC4869389,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Treatment Outcome; Adult; Female; Male; Middle Aged; Aged; Aged, 80 and over; Behavior; Risk Reduction Behavior; *Cardiovascular disease; *Cost-effectiveness analysis; *Diabetes; *Markov modelling; *Primary prevention; *Societal perspective; *Sub-Saharan Africa; *Tanzania; Angiotensin-Converting Enzyme Inhibitors/economics/therapeutic use; Aspirin/economics/therapeutic use; Calcium Channel Blockers/economics/therapeutic use; Cardiovascular Diseases/economics/*prevention & control; Diabetic Angiopathies/economics/prevention & control; Meta-Analysis as Topic; Platelet Aggregation Inhibitors/therapeutic use; Primary Prevention/economics; Risk Assessment/economics/methods; Tanzania; 1; Middle Age; Cost Benefit Analysis; 80 and Over; Clinical Trials; Preventive Health Care – Economics; Treatment Outcomes; Angiotensin-Converting Enzyme Inhibitors – Economics; Angiotensin-Converting Enzyme Inhibitors – Therapeutic Use; Aspirin – Economics; Aspirin – Therapeutic Use; Calcium Channel Blockers – Economics; Calcium Channel Blockers – Therapeutic Use; Cardiovascular Diseases – Economics; Cardiovascular Diseases – Prevention and Control; Diabetic Angiopathies – Economics; Diabetic Angiopathies – Prevention and Control; Platelet Aggregation Inhibitors – Therapeutic Use; Risk Assessment – Economics; Risk Assessment – Methods; Markov; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GVCW2XX7,journalArticle,2016,"Hamrin, Vanya; Vick, Rose; Brame, Cynthia; Simmons, Megan; Smith, Letizia; Vanderhoef, Dawn",Teaching a Systems Approach: An Innovative Quality Improvement Project.,The Journal of nursing education,,1938-2421 0148-4834,10.3928/01484834-20160316-05,,"BACKGROUND: Nurse practitioners are required to navigate complex health care systems. Quality improvement (QI) projects provide the opportunity for nurse practitioner students to learn systems knowledge and improve health care outcomes in patient populations. A gap in the literature exists around how to systematically teach, apply, and measure QI curricular objectives at the master's level. METHOD: Six faculty evaluated the QI project for the psychiatric nurse practitioner master's program by identifying the most challenging QI concepts for students to apply, revising their teaching strategies to address gaps, and retrospectively evaluating the outcomes of these curriculum changes by comparing student outcomes before and after the curricular changes. RESULTS: A significant difference was noted on QI project performance between students in the 2014 and 2015 graduating classes, measured by the scores earned on students' final papers (t[92] = 1.66, p = .05, d = .34, r(2) = .0289). CONCLUSION: Theoretical principles of adult and cooperative learning were used to inform curricular changes to enhance student's acquisition of QI skills.",2016-04,13/11/2018 10:47,14/04/2020 08:34,,209-214,,4,55,,J Nurs Educ,,,,,,,,eng,"Copyright 2016, SLACK Incorporated.",,,,,,PMID: 27023890,,,,"Humans; Adult; Clinical Competence; Female; Male; Nursing Education Research; Nursing Evaluation Research; Curriculum; Psychiatric Nursing/*education; Quality Improvement/*organization & administration; Nurse Practitioners/*education; *Organizational Innovation; Education, Nursing, Graduate/methods/*organization & administration; Educational Measurement/statistics & numerical data; Nursing Methodology Research; Systems Theory; Nursing; Education; Tennessee; Descriptive Statistics; Human; Data Analysis Software; T-Tests; Course Evaluation; Teaching Methods – Evaluation; Colleges and Universities – Tennessee; Goals and Objectives; Masters; Nurse Practitioners; Psychiatric Nursing – Education; Quality Improvement – Education; Student Knowledge – Evaluation; Student Performance Appraisal; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8FIYNEXR,journalArticle,2016,"Keane, Christopher Robert","Resilience, tipping, and hydra effects in public health: emergent collective behavior in two agent-based models.",BMC public health,,1471-2458 1471-2458,10.1186/s12889-016-2938-8,,"BACKGROUND: Collective health behavior often demonstrates counter-intuitive dynamics, sometimes resisting interventions designed to produce change, or even producing effects that are in the opposite direction than intended by the intervention, e.g. lowering infectivity resulting in increased infections. At other times collective health behavior exhibits sudden large-scale change in response to small interventions or change in the environment, a phenomenon often called ""tipping."" I hypothesize that these seemingly very different phenomena can all be explained by the same dynamic, a type of collective resilience. METHODS: I compared two simple agent-based models of interactions in networks: a public health behavior game, in which individuals decide whether or not to adopt protective behavior, and a microbial-level game, in which three different strains of bacteria attack each other. I examined the type of networks and other conditions that support a dynamic balance, and determined what changes of conditions will tip the balance. RESULTS: Both models show lasting dynamic equilibrium and resilience, resulting from negative feedback that supports oscillating coexistence of diversity under a range of conditions. In the public health game, health protection is followed by free-riding defectors, followed by a rise in infection, in long-lasting cycles. In the microbial game, each of three strains takes turns dominating. In both games, the dynamic balance is tipped by lowering the level of local clustering, changing the level of benefit, or lowering infectivity or attack rate. Lowering infectivity has the surprising effect of increasing the numbers of infected individuals. We see parallel results in the microbial game of three bacterial strains, where lowering one strain's attack rate (analogous to lowering infectivity) increases the numbers of the restrained attacker, a phenomenon captured by the phrase, ""the enemy of my enemy is my friend."" CONCLUSIONS: Collective behavior often shows a dynamic balance, resulting from negative feedback, supporting diversity and resisting change. Above certain threshold conditions, the dynamic balance is tipped towards uniformity of behavior. Under a certain range of conditions we see ""hydra effects"" in which interventions to lower attack rate or infectivity are self-defeating. Simple models of collective behavior can explain these seemingly disparate dynamics.",15/03/2016,13/11/2018 10:47,14/04/2020 08:34,,265,,,16,,BMC Public Health,,,,,,,,eng,,,,,,,PMID: 26975419 PMCID: PMC4791925,,,,"Humans; *Public Health; Decision Making; *Models, Theoretical; Public Health; System dynamics; *Choice Behavior; *Health Behavior; *Social Behavior; Interpersonal Relations; Video Games; Health Behavior; 1; Models; Theoretical; Scales; Social Behavior; 320",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, N9EM77CR,journalArticle,2017,"Doucette, William R.; Vinel, Shanrae'l; Pennathur, Priyadarshini",Initial development of the Systems Approach to Home Medication Management (SAHMM) model.,Research in social & administrative pharmacy : RSAP,,1934-8150 1551-7411,10.1016/j.sapharm.2015.12.013,,"BACKGROUND: Adverse drug events and medication nonadherence are two problems associated with prescription medication use for chronic conditions. These issues often develop because patients have difficulty managing their medications at home. To guide patients and providers for achieving safe and effective medication use at home, the Systems Approach to Home Medication Management (SAHMM) model was derived from a systems engineering model for health care workplace safety. OBJECTIVE: To explore how well concepts from the SAHMM model can represent home medication management by using patient descriptions of how they take prescription medications at home. METHODS: Twelve patients were interviewed about home medication management using an interview guide based on the factors of the SAHMM model. Each interview was audio-taped and then transcribed verbatim. Interviews were coded to identify themes for home medication management using MAXQDA for Windows. RESULTS: SAHMM concepts extracted from the coded interview transcripts included work system components of person, tasks, tools & technology, internal environment, external environment, and household. Concepts also addressed work processes and work outcomes for home medication management. CONCLUSIONS: Using the SAHMM model for studying patients' home medication management is a promising approach to improving our understanding of the factors that influence patient adherence to medication and the development of adverse drug events.",2017-02,13/11/2018 10:47,14/04/2020 08:34,,39-47,,1,13,,Res Social Adm Pharm,,,,,,,,eng,Copyright A(c) 2016 Elsevier Inc. All rights reserved.,,,,,,PMID: 26853834,,,,"Humans; Adult; Female; Male; Middle Aged; Aged; Aged, 80 and over; Drug-Related Side Effects and Adverse Reactions/*prevention & control; Chronic Disease; *Models, Theoretical; *Patient safety; Interviews as Topic; *Adverse drug event; *Medication Adherence; *Medication management; *Medication therapy; *Non-adherence; Prescription Drugs/*administration & dosage; Self Administration; Models; Theoretical; Middle Age; Scales; Interviews; 80 and Over; Medication Compliance; Adverse Drug Event – Prevention and Control; Drugs; Prescription – Administration and Dosage; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KX2X5UAW,journalArticle,2015,"Pagano, Eva; Petrelli, Alessio; Picariello, Roberta; Merletti, Franco; Gnavi, Roberto; Bruno, Graziella",Is the choice of the statistical model relevant in the cost estimation of patients with chronic diseases? An empirical approach by the Piedmont Diabetes Registry.,BMC health services research,,1472-6963 1472-6963,10.1186/s12913-015-1241-1,,"BACKGROUND: Chronic diseases impose large economic burdens. Cost analysis is not straightforward, particularly when the goal is to relate costs to specific patterns of covariates, and to compare costs between diseased and healthy populations. Using different statistical methods this study describes the impact on results and conclusions of analyzing health care costs in a population with diabetes. METHODS: Direct health care costs of people living in Turin were estimated from administrative databases of the Regional Health System. Patients with diabetes were identified through the Piedmont Diabetes Registry. The effect of diabetes on mean annual expenditure was analyzed using the following multivariable models: 1) an ordinary least squares regression (OLS); 2) a lognormal linear regression model; 3) a generalized linear model (GLM) with gamma distribution. Presence of zero cost observation was handled by means of a two part model. RESULTS: The OLS provides the effect of covariates in terms of absolute additive costs due to the presence of diabetes (euro 1,832). Lognormal and GLM provide relative estimates of the effect: the cost for diabetes would be six fold that for non diabetes patients calculated with the lognormal. The same data give a 2.6-fold increase if calculated with the GLM. Different methods provide quite different estimated costs for patients with and without diabetes, and different costs ratios between them, ranging from 3.2 to 5.6. CONCLUSIONS: Costs estimates of a chronic disease vary considerably depending on the statistical method employed; therefore a careful choice of methods to analyze data is required before inferring results.",30/12/2015,13/11/2018 10:47,14/04/2020 08:35,,582,,,15,,BMC Health Serv Res,,,,,,,,eng,,,,,,,PMID: 26714744 PMCID: PMC4696194,,,,"Humans; Health Care Costs; Adult; Female; Male; Middle Aged; Aged; Decision Making; Chronic Disease; Models, Statistical; Health Expenditures; Choice Behavior; Diabetes Mellitus, Type 1/*economics/therapy; Diabetes Mellitus, Type 2/*economics/therapy; Registries; Data Collection; Human; Models; Middle Age; Diabetes Mellitus; Type 2 – Economics; Statistical; Type 1 – Economics; Type 1 – Therapy; Type 2 – Therapy; 00; 100; 120",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EDRB7TCR,journalArticle,2016,"Mihaljevic, Susan E.; Howard, Valerie M.",Incorporating Interprofessional Evidenced-Based Sepsis Simulation Education for Certified Nursing Assistants (CNAs) and Licensed Care Providers Within Long-term Care Settings for Process and Quality Improvement.,Critical care nursing quarterly,,1550-5111 0887-9303,10.1097/CNQ.0000000000000092,,"Improving resident safety and quality of care by maximizing interdisciplinary communication among long-term care providers is essential in meeting the goals of the United States' Federal Health care reform. The new Triple Aim goals focus on improved patient outcomes, increasing patient satisfaction, and decreased health care costs, thus providing consumers with quality, efficient patient-focused care. Within the United States, sepsis is the 10th leading cause of death with a 28.6% mortality rate in the elderly, increasing to 40% to 60% in septic shock. As a result of the Affordable Care Act, the Centers for Medicare & Medicaid services supported the Interventions to Reduce Acute Care Transfers 3.0 program to improve health care quality and prevent avoidable rehospitalization by improving assessment, documentation, and communication among health care providers. The Interventions to Reduce Acute Care Transfers 3.0 tools were incorporated in interprofessional sepsis simulations throughout 19 long-term care facilities to encourage the early recognition of sepsis symptoms and prompt communication of sepsis symptoms among interdisciplinary teams. As a result of this simulation training, many long-term care organizations have adopted the STOP and WATCH and SBAR tools as a venue to communicate resident condition changes.",2016-03,13/11/2018 10:47,14/04/2020 08:34,,24-33,,1,39,,Crit Care Nurs Q,,,,,,,,eng,,,,,,,PMID: 26633155,,,,"Humans; United States; Interprofessional Relations; Simulation Training/*methods; Quality Improvement; Evidence-Based Practice; Prevalence; *Interdisciplinary Communication; *Long-Term Care; Critical Care; Nurses' Aides/*education; Patient Protection and Affordable Care Act; Sepsis/*diagnosis; Shock, Septic; Nursing; Education; Simulations; Evidence-Based; Death; Medical Practice; Nursing Assistants; Sepsis – Diagnosis; Sepsis – Epidemiology; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FQCSDX55,journalArticle,2015,"Escamilla, Veronica; Chibwesha, Carla J.; Gartland, Matthew; Chintu, Namwinga; Mubiana-Mbewe, Mwangelwa; Musokotwane, Kebby; Musonda, Patrick; Miller, William C.; Stringer, Jeffrey S. A.; Chi, Benjamin H.",Implementation and Operational Research: Distance From Household to Clinic and Its Association With the Uptake of Prevention of Mother-to-Child HIV Transmission Regimens in Rural Zambia.,Journal of acquired immune deficiency syndromes (1999),,1944-7884 1525-4135,10.1097/QAI.0000000000000739,,"BACKGROUND: In rural settings, HIV-infected pregnant women often live significant distances from facilities that provide prevention of mother-to-child transmission (PMTCT) services. METHODS: We offered universal maternal combination antiretroviral regimens in 4 pilot sites in rural Zambia. To evaluate the impact of services, we conducted a household survey in communities surrounding each facility. We collected information about HIV status and antenatal service utilization from women who delivered in the past 2 years. Using household Global Positioning System coordinates collected in the survey, we measured Euclidean (i.e., straight line) distance between individual households and clinics. Multivariable logistic regression and predicted probabilities were used to determine associations between distance and uptake of PMTCT regimens. RESULTS: From March to December 2011, 390 HIV-infected mothers were surveyed across four communities. Of these, 254 (65%) had household geographical coordinates documented. One hundred sixty-eight women reported use of a PMTCT regimen during pregnancy including 102 who initiated a combination antiretroviral regimen. The probability of PMTCT regimen initiation was the highest within 1.9 km of the facility and gradually declined. Overall, 103 of 145 (71%) who lived within 1.9 km of the facility initiated PMTCT versus 65 of 109 (60%) who lived farther away. For every kilometer increase, the association with PMTCT regimen uptake (adjusted odds ratio: 0.90, 95% confidence interval: 0.82 to 0.99) and combination antiretroviral regimen uptake (adjusted odds ratio: 0.88, 95% confidence interval: 0.80 to 0.97) decreased. CONCLUSIONS: In this rural African setting, uptake of PMTCT regimens was influenced by distance to health facility. Program models that further decentralize care into remote communities are urgently needed.",01/11/2015,13/11/2018 10:47,14/04/2020 08:34,,e94-e101,,3,70,,J Acquir Immune Defic Syndr,,,,,,,,eng,,,,,,,PMID: 26470035 PMCID: PMC4885744,,,,"Humans; Adult; Female; Young Adult; Risk Factors; Adolescent; Pregnancy; Pilot Projects; Cross-Sectional Studies; Infant, Newborn; Anti-HIV Agents/administration & dosage/*therapeutic use; HIV Infections/epidemiology/prevention & control/*transmission; Infectious Disease Transmission, Vertical/*prevention & control; Maternal-Child Health Centers/organization & administration; Odds Ratio; Pregnancy Complications, Infectious/*drug therapy; Prenatal Care/organization & administration; Rural Population; Transportation; Zambia/epidemiology; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5WD5RXBX,journalArticle,2016,"Levy, David; Mohlman, Mary Katherine; Zhang, Yian",Estimating the Potential Impact of Tobacco Control Policies on Adverse Maternal and Child Health Outcomes in the United States Using the SimSmoke Tobacco Control Policy Simulation Model.,Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco,,1469-994X 1462-2203,10.1093/ntr/ntv178,,"INTRODUCTION: Numerous studies document the causal relationship between prenatal smoking and adverse maternal and child health (MCH) outcomes. Studies also reveal the impact that tobacco control policies have on prenatal smoking. The purpose of this study is to estimate the effect of tobacco control policies on prenatal smoking prevalence and adverse MCH outcomes. METHODS: The US SimSmoke simulation model was extended to consider adverse MCH outcomes. The model estimates prenatal smoking prevalence and, applying standard attribution methods, uses estimates of MCH prevalence and relative smoking risks to estimate smoking-attributable MCH outcomes over time. The model then estimates the effect of tobacco control policies on adverse birth outcomes averted. RESULTS: Different tobacco control policies have varying impacts on the number of smoking-attributable adverse MCH birth outcomes. Higher cigarette taxes and comprehensive marketing bans individually have the biggest impact with a 5% to 10% reduction across all outcomes for the period from 2015 to 2065. The policies with the lowest impact (2%-3% decrease) during this period are cessation treatment, health warnings, and complete smoke-free laws. Combinations of all policies with each tax level lead to 23% to 28% decreases across all outcomes. CONCLUSIONS: Our findings demonstrate the substantial impact of strong tobacco control policies for preventing adverse MCH outcomes, including long-term health implications for children exposed to low birth weight and preterm birth. These benefits are often overlooked in discussions of tobacco control.",2016-05,13/11/2018 10:47,14/04/2020 08:34,,1240-1249,,5,18,,Nicotine Tob Res,,,,,,,,eng,"(c) The Author 2015. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.",,,,,,PMID: 26385929 PMCID: PMC5896820,,,,"Humans; United States; Adult; Female; Male; Middle Aged; Young Adult; Aged; Adolescent; United States/epidemiology; Pregnancy; *Models, Theoretical; Infant; Infant, Newborn; Child Health/*legislation & jurisprudence; Health Policy/*legislation & jurisprudence; Maternal Health/*legislation & jurisprudence; Premature Birth/diagnosis/epidemiology; Smoking Cessation/legislation & jurisprudence; Smoking/epidemiology/*legislation & jurisprudence; Taxes/legislation & jurisprudence; Tobacco Industry/*legislation & jurisprudence; Tobacco Products/legislation & jurisprudence; 1; Human; Models; Theoretical; Middle Age; Funding Source; Adolescence; Childbirth; Health Policy – Legislation and Jurisprudence; Industry – Legislation and Jurisprudence; Newborn; Premature – Diagnosis; Premature – Epidemiology; Smoking – Epidemiology; Smoking – Legislation and Jurisprudence; Smoking Cessation – Legislation and Jurisprudence; Taxes – Legislation and Jurisprudence; Tobacco Products – Legislation and Jurisprudence; Markov; 210",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5RJN3W83,journalArticle,2016,"Brubacher, Jacob W.; Karg, Jeffrey; Weinstock, Peter; Bae, Donald S.",A Novel Cast Removal Training Simulation to Improve Patient Safety.,Journal of surgical education,,1878-7452 1878-7452,10.1016/j.jsurg.2015.08.004,,"OBJECTIVE: Cast application and removal are essential to orthopedics and performed by providers of variable training. Simulation training and practice of proper cast application and removal may reduce injury, optimize outcomes, and reduce health care costs. The purpose of this educational initiative was to develop, validate, and implement a novel simulation trainer and curriculum to improve safety during cast removal. METHODS: In all, 30 thermocouples (Omega, Stamford, CT) were applied to a radius fracture model (Sawbones, Vashon, WA). After reduction and cast application, a saw (Stryker, Kalamazoo, MI) was used to cut the cast with temperature recording. Both ""good"" and ""poor"" techniques-as established by consensus best practices-were used. Maximal temperatures were compared to known thresholds for thermal injury; humans experience pain at temperatures exceeding 47 degrees C and contact temperatures exceeding 60 degrees C may lead to epidermal necrosis. Construct validity was evaluated by assessing novice (postgraduate year 1), intermediate (postgraduate year 3), and expert (pediatric orthopedic attending) performance. RESULTS: With the ""good"" technique, mean peak temperatures were 43 degrees C + 4.3 degrees C. The highest recorded was 51.9 degrees C. With the ""poor"" technique, mean peak temperature was 75.2 degrees C + 17.3 degrees C. The maximum temperature recorded with the ""poor"" technique was 112.4 degrees C. Construct validity testing showed that novices had the highest increases in temperatures (12.9 degrees C). There was a decline in heat generation as experience increased with the intermediate group (9.7 degrees C), and the lowest heat generation was seen in the expert group (5.0 degrees C). CONCLUSIONS: A novel task simulator and curriculum have been developed to assess competency and enhance performance in the application and removal of casts. There was a 32.2 degrees C temperature decrease when the proper cast saw technique was used. Furthermore, the ""poor"" technique consistently achieved temperatures that would cause epidermal necrosis in patients. Clinical experience was a predictor of decreased heat generation during cast removal. This task trainer allows instruction and safety monitoring of the casting technique.",2016-02,13/11/2018 10:47,14/04/2020 08:34,,07-Nov,,1,73,,J Surg Educ,,,,,,,,eng,Copyright (c) 2015 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.,,,,,,PMID: 26385318,,,,"Humans; *Curriculum; *Simulation Training; Patient Safety/*standards; patient safety; Quality Improvement; *Casts, Surgical; Manikins; orthopedics; Orthopedics/*education; Patient Care; Practice-Based Learning and Improvement; surgical simulation; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MHJZ3BUB,journalArticle,2015,"Petrescu-Prahova, Miruna; Belza, Basia; Leith, Katherine; Allen, Peg; Coe, Norma B.; Anderson, Lynda A.",Using Social Network Analysis to Assess Mentorship and Collaboration in a Public Health Network.,Preventing chronic disease,,1545-1151 1545-1151,10.5888/pcd12.150103,,"INTRODUCTION: Addressing chronic disease burden requires the creation of collaborative networks to promote systemic changes and engage stakeholders. Although many such networks exist, they are rarely assessed with tools that account for their complexity. This study examined the structure of mentorship and collaboration relationships among members of the Healthy Aging Research Network (HAN) using social network analysis (SNA). METHODS: We invited 97 HAN members and partners to complete an online social network survey that included closed-ended questions about HAN-specific mentorship and collaboration during the previous 12 months. Collaboration was measured by examining the activity of the network on 6 types of products: published articles, in-progress manuscripts, grant applications, tools, research projects, and presentations. We computed network-level measures such as density, number of components, and centralization to assess the cohesiveness of the network. RESULTS: Sixty-three respondents completed the survey (response rate, 65%). Responses, which included information about collaboration with nonrespondents, suggested that 74% of HAN members were connected through mentorship ties and that all 97 members were connected through at least one form of collaboration. Mentorship and collaboration ties were present both within and across boundaries of HAN member organizations. CONCLUSION: SNA of public health collaborative networks provides understanding about the structure of relationships that are formed as a result of participation in network activities. This approach may offer members and funders a way to assess the impact of such networks that goes beyond simply measuring products and participation at the individual level.",20/08/2015,13/11/2018 10:47,14/04/2020 08:35,,E130,,,12,,Prev Chronic Dis,,,,,,,,eng,,,,,,,PMID: 26292061 PMCID: PMC4565512,,,,Humans; Surveys and Questionnaires; United States; Health Services Research; Public Health/*methods; *Social Networking; Centers for Disease Control and Prevention (U.S.); Interdisciplinary Communication; Cross-Sectional Studies; Cooperative Behavior; *Aging; *Interinstitutional Relations; *Mentors; Capacity Building; Chronic Disease/prevention & control; Data Collection/methods; Health Planning Support; Health Services for the Aged/*organization & administration; Information Dissemination; Publishing; Sociometric Techniques; 1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CYKMYBFR,journalArticle,2015,"Jensen, Sanne",Clinical Simulation: For what and how can it be used in design and evaluation of health IT.,Studies in health technology and informatics,,0926-9630 0926-9630,,,"The usability of health information technology (IT) is increasingly recognized as critically important to the development of systems that are both safe to use and acceptable to end-users. The substantial complexity of organizations, work practice and physical environments within the healthcare sector influences the development and application of health IT. When health IT is introduced in local clinical work practices, potential patient safety hazards and insufficient support of work practices need to be examined. Qualitative methods, such as clinical simulation, may be used to support Techno-Anthropologists design and evaluate new technology navigating in the intersection between people and technology and between various interests in forms of experts and stakeholders. This chapter will introduce the reader to clinical simulation, present the general guidelines and recommendation conducting simulations and describe a simulation lab in Copenhagen. Illustrative examples and references to specific projects will be part of the contribution.",2015,13/11/2018 10:47,14/04/2020 08:34,,217-228,,,215,,Stud Health Technol Inform,,,,,,,,eng,,,,,,,PMID: 26249199,,,,"Humans; *Patient Simulation; Patient Safety; Qualitative Research; *Medical Informatics; *Technology Assessment, Biomedical; Anthropology, Cultural; Denmark; Equipment Safety; Ergonomics; Guidelines as Topic; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, R2QTRE6P,journalArticle,2015,"Penny, Melissa A.; Galactionova, Katya; Tarantino, Michael; Tanner, Marcel; Smith, Thomas A.","The public health impact of malaria vaccine RTS,S in malaria endemic Africa: country-specific predictions using 18 month follow-up Phase III data and simulation models.",BMC medicine,,1741-7015 1741-7015,10.1186/s12916-015-0408-2,,"BACKGROUND: The RTS,S/AS01 malaria vaccine candidate recently completed Phase III trials in 11 African sites. Recommendations for its deployment will partly depend on predictions of public health impact in endemic countries. Previous predictions of these used only limited information on underlying vaccine properties and have not considered country-specific contextual data. METHODS: Each Phase III trial cohort was simulated explicitly using an ensemble of individual-based stochastic models, and many hypothetical vaccine profiles. The true profile was estimated by Bayesian fitting of these models to the site- and time-specific incidence of clinical malaria in both trial arms over 18 months of follow-up. Health impacts of implementation via two vaccine schedules in 43 endemic sub-Saharan African countries, using country-specific prevalence, access to care, immunisation coverage and demography data, were predicted via weighted averaging over many simulations. RESULTS: The efficacy against infection of three doses of vaccine was initially approximately 65 % (when immunising 6-12 week old infants) and 80 % (children 5-17 months old), with a 1 year half-life (exponential decay). Either schedule will avert substantial disease, but predicted impact strongly depends on the decay rate of vaccine effects and average transmission intensity. CONCLUSIONS: For the first time Phase III site- and time-specific data were available to estimate both the underlying profile of RTS,S/AS01 and likely country-specific health impacts. Initial efficacy will probably be high, but decay rapidly. Adding RTS,S to existing control programs, assuming continuation of current levels of malaria exposure and of health system performance, will potentially avert 100-580 malaria deaths and 45,000 to 80,000 clinical episodes per 100,000 fully vaccinated children over an initial 10-year phase.",29/07/2015,13/11/2018 10:47,14/04/2020 08:35,,170,,,13,,BMC Med,,,,,,,,eng,,,,,,,PMID: 26219380 PMCID: PMC4518512,,,,"Humans; Treatment Outcome; Adult; Middle Aged; Young Adult; Follow-Up Studies; Child; Adolescent; Incidence; Infant; Prevalence; Africa South of the Sahara/epidemiology; Malaria Vaccines/*therapeutic use; Malaria, Falciparum/epidemiology; Malaria/epidemiology/*prevention & control; Public Health/*statistics & numerical data; Vaccination/*statistics & numerical data; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PDLBHA7T,journalArticle,2017,"Vanamala, Jairam",Food systems approach to cancer prevention.,Critical reviews in food science and nutrition,,1549-7852 1040-8398,10.1080/10408398.2015.1028023,,"New cancer cases are expected to surge 57% worldwide in the next two decades. The greatest burden will be in low- and middle-income countries that are ill equipped to face this epidemic. Similarly, in the United States, low-income populations are at greater risk for cancer. As most cancers contain over 50 genetic alterations, and as these alterations define dysregulation of over 10 different critical cellular signaling pathways, a ""silver bullet"" treatment is not effective against most cancers. Instead, the latest World Cancer Report (2012) suggests a research shift toward developing prevention strategies for cancer. Accumulating evidence suggests that a diet high in plant-based foods is preventive of a variety of chronic diseases, including cancer. A plethora of bioactive compounds-such as polyphenols, glucosinolates and carotenoids in fruits, vegetables, grains, and legumes-are shown to suppress a variety of biological capabilities required for tumor growth. While much research has shown that plant bioactive compounds can suppress sustained proliferative signaling, angiogenesis, and metastasis, as well as promote cancer stem cell apoptosis, public health campaigns to increase fruit and vegetable consumption have, overall, been less effective than desired. Thus, there is a need for innovative strategies to support increased consumption of bioactive compounds for cancer prevention particularly in vulnerable populations. Many practices of the farm-to-fork continuum, including preharvest practices, postharvest storage, and processing and consumer practices, affect a food's bioactive compound content, composition, and chemopreventive bioactivity. Food system practices may be adjusted to reduce the toxic compound levels (e.g., glycoalkaloids in potatoes) and improve the bioactive compound profile, thus, elevate the cancer fighting properties of fruits, vegetables, and other food products. This review presents current scientific evidence outlining farm-to-fork effects on fruit and vegetable bioactive compounds in order to aid the development of new and reasonable strategies for cancer prevention.",13/08/2017,13/11/2018 10:47,14/04/2020 08:35,,2573-2588,,12,57,,Crit Rev Food Sci Nutr,,,,,,,,eng,,,,,,,PMID: 26192392,,,,Humans; *Diet; Systems Analysis; Diet; cancer prevention; cancer stem cells; carotenoids; flavonoids; Food systems; Fruit; glucosinolates; Neoplasms/*prevention & control; polyphenols; processing; Vegetables; Neoplasms – Prevention and Control; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6PAGCPWW,journalArticle,2015,"Weiss, Jennifer; Makonnen, Raphael; Sula, Delphin",Shifting management of a community volunteer system for improved child health outcomes: results from an operations research study in Burundi.,BMC health services research,,1472-6963 1472-6963,10.1186/1472-6963-15-S1-S2,,"BACKGROUND: Community-based strategies that foster frequent contact between caregivers of children under five and provide credible sources of health information are essential to improve child survival. Care Groups are a community-based implementation strategy for the delivery of social and behavior change interventions. This study assessed if supervision of Care Group activities by Ministry of Health (MOH) personnel could achieve the same child health outcomes as supervision provided by specialized non-governmental organization (NGO) staff. METHODS: The study was a pretest-posttest quasi-experimental design implemented in Burundi. A total of 45 MOH-led Care Groups with 478 Care Group Volunteers (CGVs) were established in the intervention area; and 50 NGO-led Care Groups with 509 CGVs were formed in the comparison area. Data were collected from 593 and 700 mothers of children 0-23 months at baseline and endline, respectively. Pearson's chi-squared test and difference-in-difference analysis assessed changes in 40 child health and nutrition outcomes. A qualitative process evaluation was also conducted midway through the study. RESULTS: The MOH-led Care Group model performed at least as well as the NGO-led model in achieving specific child health and nutrition outcomes. Mothers of children 0-23 months in the intervention and comparison sites reported similar levels of knowledge and practices for 38 of 40 dependent variables measured in the study, and these results remained unchanged after accounting for differences in the indicator values at baseline. Process monitoring data confirmed that the MOH-led Care Group model and the NGO-led Care Group model were implemented with similar intervention strength. CONCLUSIONS: The study demonstrated that behavior change interventions traditionally led by NGOs can be implemented through the existing MOH systems and achieve similar results, thereby increasing the potential for sustainable child health outcomes. Future research on the MOH-led Care Group model is required to systematically document all inputs and monetary costs borne by the MOH to implement the model.",2015,13/11/2018 10:47,14/04/2020 08:35,,S2,,,15 Suppl 1,,BMC Health Serv Res,,,,,,,,eng,,,,,,,PMID: 26062624 PMCID: PMC4464208,,,,"Humans; Socioeconomic Factors; Health Status Indicators; Adult; Female; Male; Infant; Health Knowledge, Attitudes, Practice; Community Health Services/*organization & administration; Infant, Newborn; Operations Research; *Volunteers; Burundi; Child Health Services/*organization & administration; Financing, Government/*organization & administration; Health Promotion/*organization & administration; Mothers/*education; Private Sector/*organization & administration; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9DCB9DNN,journalArticle,2015,"Perlin, Jonathan B.; Mower, Laura; Bushe, Chris","A systems approach to evaluating ionizing radiation: six focus areas to improve quality, efficiency, and patient safety.",Journal for healthcare quality : official publication of the National Association for Healthcare Quality,,1945-1474 1062-2551,10.1111/JHQ-D-15-00038,,"Ionizing radiation is an essential component of the care process. However, providers and patients may not be fully aware of the risks involved, the level of ionizing radiation delivered with various procedures, or the potential for harm through incidental overexposure or cumulative dose. Recent high-profile incidents demonstrating the devastating short-term consequences of radiation overexposure have drawn attention to these risks, but applicable solutions are lacking. Although various recommendations and guidelines have been proposed, organizational variability challenges providers to identify their own practical solutions. To identify potential failure modes and develop solutions to preserve patient safety within a large, national healthcare system, we assembled a multidisciplinary team to conduct a comprehensive analysis of practices surrounding the delivery of ionizing radiation. Workgroups were developed to analyze existing culture, processes, and technology to identify deficiencies and propose solutions. Six focus areas were identified: competency and certification; equipment; monitoring and auditing; education; clinical pathways; and communication and marketing. This manuscript summarizes this comprehensive, multidisciplinary, and systemic analysis of risk and provides examples to illustrate how these focus areas can be used to improve the use of ionizing radiation. The proposed solutions, once fully implemented, may advance patient safety and care.",2015-06,13/11/2018 10:47,14/04/2020 08:35,,173-188,,3,37,,J Healthc Qual,,,,,,,,eng,,,,,,,PMID: 26042626 PMCID: PMC4617287,,,,"Humans; Quality of Health Care; Patient Safety; Risk Assessment; *Systems Analysis; Systems Analysis; Communication; *Patient Safety; Quality Improvement/*organization & administration; Efficiency, Organizational; Certification/standards; Critical Pathways/standards; Multi-Institutional Systems; Radiation, Ionizing; Radiologic Health/*methods/*organization & administration/standards; Technology, Radiologic; Professional Competence; Radiation Dosage; 1; Program Implementation; Professional Development; Certification; Hospital Policies; Ionizing; Multiinstitutional Systems; Organizational Efficiency; Radiation; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, W3IT6CFE,journalArticle,2015,"McCoy, Sandra I.; Buzdugan, Raluca; Padian, Nancy S.; Musarandega, Reuben; Engelsmann, Barbara; Martz, Tyler E.; Mushavi, Angela; Mahomva, Agnes; Cowan, Frances M.",Implementation and Operational Research: Uptake of Services and Behaviors in the Prevention of Mother-to-Child HIV Transmission Cascade in Zimbabwe.,Journal of acquired immune deficiency syndromes (1999),,1944-7884 1525-4135,10.1097/QAI.0000000000000597,,"OBJECTIVE: To examine the uptake of services and behaviors in the prevention of mother-to-child HIV transmission (PMTCT) cascade in Zimbabwe and to determine factors associated with MTCT and maternal antiretroviral therapy (ART) or antiretroviral (ARV) prophylaxis. DESIGN: Analysis of cross-sectional data from mother-infant pairs. METHODS: We analyzed baseline data collected in 2012 as part of the impact evaluation of Zimbabwe's Accelerated National PMTCT Program. Using multistage cluster sampling, eligible mother-infant pairs were randomly sampled from the catchment areas of 157 facilities in 5 provinces, tested for HIV infection, and interviewed about PMTCT service utilization. RESULTS: Of 8800 women, 94% attended >/= 1 antenatal care visit, 92% knew their HIV serostatus during pregnancy, 77% delivered in a health facility, and 92% attended the 6-8 week postnatal visit. Among 1075 (12%) HIV-infected women, 59% reported ART/ARV prophylaxis and 63% of their HIV-exposed infants received ARV prophylaxis. Among",01/06/2015,13/11/2018 10:47,14/04/2020 08:34,,e74-81,,2,69,,J Acquir Immune Defic Syndr,,,,,,,,eng,,,,,,,PMID: 26009838 PMCID: PMC4445469,,,,"Humans; Adult; Female; Young Adult; Adolescent; Pregnancy; Infant; Cross-Sectional Studies; Infant, Newborn; Zimbabwe; Data Collection; Public Health Administration/*methods; Infectious Disease Transmission, Vertical/*prevention & control; Pregnancy Complications, Infectious/*drug therapy; *Patient Acceptance of Health Care; Anti-Retroviral Agents/therapeutic use; Chemoprevention/methods; HIV Infections/*drug therapy/*prevention & control; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 98TJT3QB,journalArticle,2015,"Were, Martin C.; Kessler, Jason; Shen, Changyu; Sidle, John; Macharia, Stephen; Lizcano, John; Siika, Abraham; Wools-Kaloustian, Kara; Kurth, Ann",Implementation and Operational Research: A Time-Motion Analysis of HIV Transmission Prevention Counseling and Antiretroviral Adherence Messages in Western Kenya.,Journal of acquired immune deficiency syndromes (1999),,1944-7884 1525-4135,10.1097/QAI.0000000000000666,,"BACKGROUND: Shortages of health workers and large number of HIV-infected persons in Africa mean that time to provide antiretroviral therapy (ART) adherence and other messages to patients is limited. METHODS: Using time-motion methodology, we documented the intensity and nature of counseling delivered to patients. The study was conducted at a rural and an urban HIV clinic in western Kenya. We recorded all activities of 190 adult patients on ART during their return clinic visits to assess type, frequency, and duration of counseling messages. RESULTS: Mean visit length for patients at the rural clinic was 44.5 (SD = 27.9) minutes and at urban clinic was 78.2 (SD = 42.1) minutes. Median time spent receiving any counseling during a visit was 4.07 minutes [interquartile range (IQR), 1.57-7.33] at rural and 3.99 (IQR, 2.87-6.25) minutes at urban, representing 11% and 8% of total mean visit time, respectively. Median time patients received ART adherence counseling was 1.29 (IQR, 0.77-2.83) minutes at rural and 1.76 (IQR, 1.23-2.83) minutes at urban (P = 0.001 for difference). Patients received a median time of 0.18 (0-0.72) minutes at rural and 0.28 (IQR, 0-0.67) minutes at urban clinic of counseling regarding contraception and pregnancy. Most patients in the study did not receive any counseling regarding alcohol/substance use, emerging risks for ongoing HIV transmission. CONCLUSIONS: Although ART adherence was discussed with most patients, time was limited. Reproductive counseling was provided to only half of the patients, and ""positive prevention"" messaging was minimal. There are strategic opportunities to enhance counseling and information received by clients within HIV programs in resource-limited settings.",01/08/2015,13/11/2018 10:47,14/04/2020 08:35,,e135-141,,4,69,,J Acquir Immune Defic Syndr,,,,,,,,eng,,,,,,,PMID: 25950208 PMCID: PMC4683585,,,,Humans; Adult; Health Personnel; *Medication Adherence; Anti-HIV Agents/*administration & dosage/*therapeutic use; Community Health Centers/*manpower/statistics & numerical data/supply & distribution; Health Manpower; HIV Infections/*prevention & control/*transmission; Time and Motion Studies; 00; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UJ5H4EJW,journalArticle,2015,"Liu, Fengchen; Enanoria, Wayne T. A.; Zipprich, Jennifer; Blumberg, Seth; Harriman, Kathleen; Ackley, Sarah F.; Wheaton, William D.; Allpress, Justine L.; Porco, Travis C.","The role of vaccination coverage, individual behaviors, and the public health response in the control of measles epidemics: an agent-based simulation for California.",BMC public health,,1471-2458 1471-2458,10.1186/s12889-015-1766-6,,"BACKGROUND: Measles cases continue to occur among susceptible individuals despite the elimination of endemic measles transmission in the United States. Clustering of disease susceptibility can threaten herd immunity and impact the likelihood of disease outbreaks in a highly vaccinated population. Previous studies have examined the role of contact tracing to control infectious diseases among clustered populations, but have not explicitly modeled the public health response using an agent-based model. METHODS: We developed an agent-based simulation model of measles transmission using the Framework for Reconstructing Epidemiological Dynamics (FRED) and the Synthetic Population Database maintained by RTI International. The simulation of measles transmission was based on interactions among individuals in different places: households, schools, daycares, workplaces, and neighborhoods. The model simulated different levels of immunity clustering, vaccination coverage, and contact investigations with delays caused by individuals' behaviors and/or the delay in a health department's response. We examined the effects of these characteristics on the probability of uncontrolled measles outbreaks and the outbreak size in 365 days after the introduction of one index case into a synthetic population. RESULTS: We found that large measles outbreaks can be prevented with contact investigations and moderate contact rates by having (1) a very high vaccination coverage (>/= 95%) with a moderate to low level of immunity clustering (/=51 mm, rate >100 per minute, and >/=95% full recoil). Survival rates were calculated from the feedback device and manikin data. RESULTS: The survival rate according to the feedback device data was 80%; however, the manikin data indicated a significantly lower survival rate (46.7%; P = .015). The difference between the accelerometer and manikin survival rates was not significant for participants with a body mass index greater than or equal to 20 kg/m(2) (93.3 vs 73.3%, respectively; P = .330); however, the difference in survival rate was significant in participants with body mass index less than 20 kg/m(2) (66.7 vs 20.0%, respectively; P = .025). CONCLUSIONS: The use of accelerometer feedback devices to facilitate high-quality chest compression may not be appropriate for lightweight rescuers because of the potential for compression depth overestimation. TRIAL REGISTRATION: Clinical Research Information Service (KCT0001449).",2015-08,13/11/2018 10:47,14/04/2020 08:34,,993-997,,8,33,,Am J Emerg Med,,,,,,,,eng,Copyright (c) 2015 Elsevier Inc. All rights reserved.,,,,,,PMID: 25921966,,,,Humans; Adult; Female; Male; Young Adult; Heart Arrest/*therapy; *Health Personnel; Prospective Studies; Survival Rate; Health Personnel; Manikins; *Feedback; *Accelerometry; Heart Massage/*standards; Feedback; Human; Models; Accelerometry; Anatomic; Heart Arrest – Therapy; Heart Massage – Standards; Survival; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UZSNJVZI,journalArticle,2014,"Suri, Devika J.; Tano-Debrah, Kwaku; Ghosh, Shibani A.",Optimization of the nutrient content and protein quality of cereal-legume blends for use as complementary foods in Ghana.,Food and nutrition bulletin,,0379-5721 0379-5721,10.1177/156482651403500309,,"BACKGROUND: Nutritionally adequate complementary foods made from locally available ingredients are of high priority in developing countries, including Ghana. The majority of complementary foods in these countries are cereal-based and are unable to meet the nutrient intakes recommended by the World Health Organization. OBJECTIVE: To evaluate the nutrient content and protein quality of local cereal-legume blends for complementary foods against recommendations and to determine the quantities of additional ingredients required to meet needs by using linear programming. METHODS: Nine cereal-legume combinations (maize, sorghum, or millet combined with cowpea, peanut, or soybean) and koko (a traditional Ghanaian maize-based complementary food) were evaluated based on the macronutrient targets for a daily ration of complementary food for the age group 12 to 24 months: 264 kcal, 6.5 g of protein, and 8.2 to 11.7 g of fat. Protein quality was assessed by the Protein Digestibility Corrected Amino Acid Score (PDCAAS). Linear programming was then used to determine the amounts of additional oil, sugar, and lysine needed to meet macronutrient requirements. RESULTS: No traditional cereal-legume food met all complementary food macronutrient requirements on its own. Cereal-legume blends made with peanut or cowpeas were low in quality protein, while those with soybean were low in fat. Lysine was the limiting amino acid (PDCAAS 0.50 to 0.82) in all blends. Adding lysine increased utilizable protein by 1% to 10% in soybean blends, 35% to 40% in peanut blends, and 14% to 24% in cowpea blends. Peanut-maize, peanut-millet, and all soybean-cereal blends were able to meet macronutrient targets; most micronutrients remained below recommended levels. CONCLUSIONS: Traditional cereal-legume blends made from locally available ingredients do not meet energy, quality protein, and fat recommendations for complementary foods; however, such complementary food blends may be optimized to meet nutrient requirements by using linear programming as a tool to determine the exact levels of fortificants to be added (including, but not limited to, added fat, amino acids, and micronutrients).",2014-09,13/11/2018 10:47,14/04/2020 08:35,,372-381,,3,35,,Food Nutr Bull,,,,,,,,eng,,,,,,,PMID: 25902596,,,,"Humans; Child; Child, Preschool; Infant; *Edible Grain; *Fabaceae; *Infant Nutritional Physiological Phenomena; *Nutritive Value; Arachis; Dietary Fats/analysis; Dietary Proteins/*analysis; Energy Intake; Food Quality; Ghana; Infant Food/analysis; Lysine/administration & dosage; Micronutrients/analysis; Nutritional Requirements; Soybeans; Zea mays; Human; Cereals; Corn; Dietary Fats – Analysis; Dietary Proteins – Analysis; Infant Food – Analysis; Infant Nutritional Physiology; Legumes; Lysine – Administration and Dosage; Micronutrients – Analysis; Nutritive Value; Peanut; Preschool; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9I8AUSFZ,journalArticle,2015,"Yajamanyam, Phani Kiran; Sohi, Dalbir",In situ simulation as a quality improvement initiative.,Archives of disease in childhood. Education and practice edition,,1743-0593 1743-0585,10.1136/archdischild-2014-306939,,"Simulation-based learning has gained recent recognition as a means of improving patient safety. In situ simulation, that is conducting simulation training in actual clinical environment, is a novel approach to detecting deficiencies in healthcare systems, termed as latent safety threats (LSTs). We implemented in situ simulation training as a quality improvement initiative and were able to detect several LSTs, thus improving patient safety.",2015-06,13/11/2018 10:47,14/04/2020 08:35,,162-163,,3,100,,Arch Dis Child Educ Pract Ed,,,,,,,,eng,Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.,,,,,,PMID: 25852214,,,,"Humans; *Quality Improvement; Child; Simulation Training/*methods; Infant, Newborn; Accident & Emergency; Emergency Service, Hospital/*standards; Intensive Care Units, Neonatal/*standards; Medical Education; Neonatology; Technology; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PCQHLLDB,journalArticle,2015,"Mariani, Bette; Cantrell, Mary Ann; Meakim, Colleen; Jenkinson, Amanda",Improving students' safety practice behaviors through a simulation-based learning experience.,The Journal of nursing education,,1938-2421 0148-4834,10.3928/01484834-20150218-05,,"This study evaluated 175 senior-level undergraduate nursing students' perceptions and comfort level regarding safety principles and practices before and after participating in a safety-focused clinical simulation-based experience during their nursing leadership course. The Healthcare Professionals Patient Safety Assessment (HPPSA) was used to measure students' perceptions and comfort level regarding patient safety practices. Respondents rated their level of agreement about statements related to errors and safety in health care, their comfort level in reporting and disclosing an error, and whether they had seen, disclosed, or reported an error. The t test for the HPPSA Part 2 was statistically significant (n = 153, t = 2.78, p = 0.006) with mean pretest and posttest scores of 16.95 (SD = 3.44) and 17.69 (SD = 3.25), respectively. The findings suggest simulation is a teaching strategy that may contribute to increasing undergraduate nursing students' comfort with reporting or investigating errors.",2015-03,13/11/2018 10:47,14/04/2020 08:34,,S35-38,,3 Suppl,54,,J Nurs Educ,,,,,,,,eng,"Copyright 2015, SLACK Incorporated.",,,,,,PMID: 25692409,,,,"Humans; Adult; Female; Male; Middle Aged; *Clinical Competence; *Patient Safety; Leadership; *Education, Nursing, Baccalaureate; *Self Concept; Problem-Based Learning/*organization & administration; Truth Disclosure; Nursing; Education; Descriptive Statistics; Human; Pretest-Posttest Design; Baccalaureate; Data Analysis Software; T-Tests; Simulations; Patient Safety – Education; Questionnaires; Funding Source; Nonexperimental Studies; Surveys; Videorecording; Student Experiences; Leadership – Education; Health Care Errors; Paired T-Tests; Clinical Conferences; Comfort – Evaluation; Incident Reports; Perception – Evaluation; Student Attitudes – Evaluation; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8YQ6LRNB,journalArticle,2015,"Wang, Youfa; Xue, Hong; Liu, Shiyong","Applications of systems science in biomedical research regarding obesity and noncommunicable chronic diseases: opportunities, promise, and challenges.","Advances in nutrition (Bethesda, Md.)",,2156-5376 2161-8313,10.3945/an.114.007203,,"Interest in the application of systems science (SS) in biomedical research, particularly regarding obesity and noncommunicable chronic disease (NCD) research, has been growing rapidly over the past decade. SS is a broad term referring to a family of research approaches that include modeling. As an emerging approach being adopted in public health, SS focuses on the complex dynamic interaction between agents (e.g., people) and subsystems defined at different levels. SS provides a conceptual framework for interdisciplinary and transdisciplinary approaches that address complex problems. SS has unique advantages for studying obesity and NCD problems in comparison to the traditional analytic approaches. The application of SS in biomedical research dates back to the 1960s with the development of computing capacity and simulation software. In recent decades, SS has been applied to addressing the growing global obesity epidemic. There is growing appreciation and support for using SS in the public health field, with many promising opportunities. There are also many challenges and uncertainties, including methodologic, funding, and institutional barriers. Integrated efforts by stakeholders that address these challenges are critical for the successful application of SS in the future.",2015-01,13/11/2018 10:47,14/04/2020 08:35,,88-95,,1,6,,Adv Nutr,,,,,,,,eng,(c) 2015 American Society for Nutrition.,,,,,,PMID: 25593147 PMCID: PMC4288284,,,,"Humans; Research; Public Health/*methods; *Models, Theoretical; systems science; Systems Theory; *Chronic Disease/therapy; *Obesity/therapy; *Systems Theory; Biomedical Research/*methods; child; intervention; models; noncommunicable chronic diseases; obesity; policy; Science; simulation; Models; Theoretical; Public Health – Methods; Chronic Disease – Therapy; Medical – Methods; Obesity – Therapy; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RGNQKR4J,journalArticle,2014,"Anota, Amelie; Barbieri, Antoine; Savina, Marion; Pam, Alhousseiny; Gourgou-Bourgade, Sophie; Bonnetain, Franck; Bascoul-Mollevi, Caroline",Comparison of three longitudinal analysis models for the health-related quality of life in oncology: a simulation study.,Health and quality of life outcomes,,1477-7525 1477-7525,10.1186/s12955-014-0192-2,,"BACKGROUND: Health-Related Quality of Life (HRQoL) is an important endpoint in oncology clinical trials aiming to investigate the clinical benefit of new therapeutic strategies for the patient. However, the longitudinal analysis of HRQoL remains complex and unstandardized. There is clearly a need to propose accessible statistical methods and meaningful results for clinicians. The objective of this study was to compare three strategies for longitudinal analyses of HRQoL data in oncology clinical trials through a simulation study. METHODS: The methods proposed were: the score and mixed model (SM); a survival analysis approach based on the time to HRQoL score deterioration (TTD); and the longitudinal partial credit model (LPCM). Simulations compared the methods in terms of type I error and statistical power of the test of an interaction effect between treatment arm and time. Several simulation scenarios were explored based on the EORTC HRQoL questionnaires and varying the number of patients (100, 200 or 300), items (1, 2 or 4) and response categories per item (4 or 7). Five or 10 measurement times were considered, with correlations ranging from low to high between each measure. The impact of informative missing data on these methods was also studied to reflect the reality of most clinical trials. RESULTS: With complete data, the type I error rate was close to the expected value (5%) for all methods, while the SM method was the most powerful method, followed by LPCM. The power of TTD is low for single-item dimensions, because only four possible values exist for the score. When the number of items increases, the power of the SM approach remained stable, those of the TTD method increases while the power of LPCM remained stable. With 10 measurement times, the LPCM was less efficient. With informative missing data, the statistical power of SM and TTD tended to decrease, while that of LPCM tended to increase. CONCLUSIONS: To conclude, the SM model was the most powerful model, irrespective of the scenario considered, and the presence or not of missing data. The TTD method should be avoided for single-item dimensions of the EORTC questionnaire. While the LPCM model was more adapted to this kind of data, it was less efficient than the SM model. These results warrant validation through comparisons on real data.",31/12/2014,13/11/2018 10:47,14/04/2020 08:34,,192,,,12,,Health Qual Life Outcomes,,,,,,,,eng,,,,,,,PMID: 25551580 PMCID: PMC4326524,,,,"Humans; Female; Male; *Models, Theoretical; Health Status; Longitudinal Studies; *Health Status Indicators; *Patient Outcome Assessment; Medical Oncology; Neoplasms/*psychology/therapy; Quality of Life/*psychology; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6JIW8FUW,journalArticle,2014,"Park, Yukyung; Kim, Chang-Yup; You, Myoung Soon; Lee, Kun Sei; Park, Eunyoung","Public participation in the process of local public health policy, using policy network analysis.",Journal of preventive medicine and public health = Yebang Uihakhoe chi,,2233-4521 1975-8375,10.3961/jpmph.14.029,,"OBJECTIVES: To assess the current public participation in-local health policy and its implications through the analysis of policy networks in health center programs. METHODS: We examined the decision-making process in sub-health center installations and the implementation process in metabolic syndrome management program cases in two districts ('gu's) of Seoul. Participants of the policy network were selected by the snowballing method and completed self-administered questionnaires. Actors, the interactions among actors, and the characteristics of the network were analyzed by Netminer. RESULTS: The results showed that the public is not yet actively participating in the local public health policy processes of decision-making and implementation. In the decision-making process, most of the network actors were in the public sector, while the private sector was a minor actor and participated in only a limited number of issues after the major decisions were made. In the implementation process, the program was led by the health center, while other actors participated passively. CONCLUSIONS: Public participation in Korean public health policy is not yet well activated. Preliminary discussions with various stakeholders, including civil society, are needed before making important local public health policy decisions. In addition, efforts to include local institutions and residents in the implementation process with the public officials are necessary to improve the situation.",2014-11,13/11/2018 10:47,14/04/2020 08:35,,298-308,,6,47,,J Prev Med Public Health,,,,,,,,eng,,,,,,,PMID: 25475197 PMCID: PMC4263003,,,,*Health Policy; Humans; Surveys and Questionnaires; Decision Making; Program Development; *Community Participation; Community Networks; Health Services Needs and Demand; Local public health policy; Metabolic Syndrome/prevention & control; Policy network; Policy process; Public participation; Social network analysis; 1; ******To read; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HLED7KG5,journalArticle,2014,"Schoen, Martin W.; Moreland-Russell, Sarah; Prewitt, Kim; Carothers, Bobbi J.",Social network analysis of public health programs to measure partnership.,Social science & medicine (1982),,1873-5347 0277-9536,10.1016/j.socscimed.2014.10.057,,"In order to prevent chronic diseases, community-based programs are encouraged to take an ecological approach to public health promotion and involve many diverse partners. Little is known about measuring partnership in implementing public health strategies. We collected data from 23 Missouri communities in early 2012 that received funding from three separate programs to prevent obesity and/or reduce tobacco use. While all of these funding programs encourage partnership, only the Social Innovation for Missouri (SIM) program included a focus on building community capacity and enhancing collaboration. Social network analysis techniques were used to understand contact and collaboration networks in community organizations. Measurements of average degree, density, degree centralization, and betweenness centralization were calculated for each network. Because of the various sizes of the networks, we conducted comparative analyses with and without adjustment for network size. SIM programs had increased measurements of average degree for partner collaboration and larger networks. When controlling for network size, SIM groups had higher measures of network density and lower measures of degree centralization and betweenness centralization. SIM collaboration networks were more dense and less centralized, indicating increased partnership. The methods described in this paper can be used to compare partnership in community networks of various sizes. Further research is necessary to define causal mechanisms of partnership development and their relationship to public health outcomes.",2014-12,13/11/2018 10:47,14/04/2020 08:35,,90-95,,,123,,Soc Sci Med,,,,,,,,eng,Copyright (c) 2014 Elsevier Ltd. All rights reserved.,,,,,,PMID: 25462609,,,,Humans; Health Promotion; Surveys and Questionnaires; *Public Health; Public Health; Smoking Cessation; *Social Support; Public health; *Health Promotion; Social network analysis; *Community Networks/organization & administration; Collaboration; Community research; Missouri; Obesity prevention; Obesity/prevention & control; Partnership; Tobacco cessation; Social Networks; 1; Human; Program Implementation; Obesity – Prevention and Control; Smoking – Prevention and Control; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7C565X67,journalArticle,2014,"Leinhos, Mary; Qari, Shoukat H.; Williams-Johnson, Mildred",Preparedness and emergency response research centers: using a public health systems approach to improve all-hazards preparedness and response.,"Public health reports (Washington, D.C. : 1974)",,1468-2877 0033-3549,10.1177/00333549141296S403,,"In 2008, at the request of the Centers for Disease Control and Prevention (CDC), the Institute of Medicine (IOM) prepared a report identifying knowledge gaps in public health systems preparedness and emergency response and recommending near-term priority research areas. In accordance with the Pandemic and All-Hazards Preparedness Act mandating new public health systems research for preparedness and emergency response, CDC provided competitive awards establishing nine Preparedness and Emergency Response Research Centers (PERRCs) in accredited U.S. schools of public health. The PERRCs conducted research in four",2014,13/11/2018 10:47,14/04/2020 08:34,,Aug-18,,,129 Suppl 4,,Public Health Rep,,,,,,,,eng,,,,,,,PMID: 25355970 PMCID: PMC4187302,,,,"Humans; United States; Research; Quality Improvement; Centers for Disease Control and Prevention (U.S.); Systems Theory; *Research; Civil Defense/organization & administration; Disaster Planning/*organization & administration; National Academies of Science, Engineering, and Medicine (U.S.) Health and Medicine Division; Organizational Objectives; Public Health/*education; Public-Private Sector Partnerships; Research Support as Topic; Schools, Public Health/*organization & administration; Disaster Planning; Accreditation; Benchmarking; Interinstitutional Relations; Conceptual Framework; Professional Practice; Interdisciplinary; Research Support; Management; Institute of Medicine (U.S.); Colleges and Universities – Classification – United States; Early Intervention; Financing; Goal Attainment; Government; Government Agencies; Public Health – Education; Reports; Research – Organizations; Research Priorities; Research-Based; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UU7HXPDN,journalArticle,2014,"Pinnock, Hilary; Ehrlich, Elisabeth; Hoskins, Gaylor; Tomlins, Ron",A woman with asthma: a whole systems approach to supporting self-management.,NPJ primary care respiratory medicine,,2055-1010 2055-1010,10.1038/npjpcrm.2014.63,,"A 35-year-old lady attends for review of her asthma following an acute exacerbation. There is an extensive evidence base for supported self-management for people living with asthma, and international and national guidelines emphasise the importance of providing a written asthma action plan. Effective implementation of this recommendation for the lady in this case study is considered from the perspective of a patient, healthcare professional, and the organisation. The patient emphasises the importance of developing a partnership based on honesty and trust, the need for adherence to monitoring and regular treatment, and involvement of family support. The professional considers the provision of asthma self-management in the context of a structured review, with a focus on a self-management discussion which elicits the patient's goals and preferences. The organisation has a crucial role in promoting, enabling and providing resources to support professionals to provide self-management. The patient's asthma control was assessed and management optimised in two structured reviews. Her goal was to avoid disruption to her work and her personalised action plan focused on achieving that goal.",16/10/2014,13/11/2018 10:47,14/04/2020 08:35,,14063,,,24,,NPJ Prim Care Respir Med,,,,,,,,eng,,,,,,,PMID: 25321880 PMCID: PMC4373456,,,,Humans; Adult; Female; *Self Care; Asthma/*therapy; Patient Care Planning; 1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, G9EBKZYV,journalArticle,2014,"Aebersold, Michelle; Titler, Marita G.",A simulation model for improving learner and health outcomes.,The Nursing clinics of North America,,1558-1357 0029-6465,10.1016/j.cnur.2014.05.011,,"Simulation has become a necessary and integral part of education for prelicensure and ongoing education of health care practitioners. To guide this process, the Simulation Model for Improving Learner and Health Outcomes (SMILHO) model provides a framework to design the experience from a science of learning approach and links it to learner and health outcomes to add to the knowledge base. Much work has been done in this area, and the SMILHO model will support the future work needed to continue to create effective simulation-based learning experiences and move research from knowledge and skill evaluation to learner and health outcomes.",2014-09,13/11/2018 10:47,14/04/2020 08:34,,431-439,,3,49,,Nurs Clin North Am,,,,,,,,eng,Copyright (c) 2014 Elsevier Inc. All rights reserved.,,,,,,PMID: 25155540,,,,"Humans; *Patient Simulation; *Models, Educational; Simulation; *Learning; *Outcome Assessment (Health Care); Best practices; Education, Professional/*methods; Health outcomes; Learner outcomes; Model; Simulation-based learning; 1; ****; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9FPBQLKP,journalArticle,2015,"Piette, John D.; Farris, Karen B.; Newman, Sean; An, Larry; Sussman, Jeremy; Singh, Satinder",The potential impact of intelligent systems for mobile health self-management support: Monte Carlo simulations of text message support for medication adherence.,Annals of behavioral medicine : a publication of the Society of Behavioral Medicine,,1532-4796 0883-6612,10.1007/s12160-014-9634-7,,"BACKGROUND: Mobile health (mHealth) services cannot easily adapt to users' unique needs. PURPOSE: We used simulations of text messaging (SMS) for improving medication adherence to demonstrate benefits of interventions using reinforcement learning (RL). METHODS: We used Monte Carlo simulations to estimate the relative impact of an intervention using RL to adapt SMS adherence support messages in order to more effectively address each non-adherent patient's adherence barriers, e.g., forgetfulness versus side effect concerns. SMS messages were assumed to improve adherence only when they matched the barriers for that patient. Baseline adherence and the impact of matching messages were estimated from literature review. RL-SMS was compared in common scenarios to simple reminders, random messages, and standard tailoring. RESULTS: RL could produce a 5-14% absolute improvement in adherence compared to current approaches. When adherence barriers are not accurately reported, RL can recognize which barriers are relevant for which patients. When barriers change, RL can adjust message targeting. RL can detect when messages are sent too frequently causing burnout. CONCLUSIONS: RL systems could make mHealth services more effective.",2015-02,13/11/2018 10:47,14/04/2020 08:34,,84-94,,1,49,,Ann Behav Med,,,,,,,,eng,,,,,,,PMID: 25082177 PMCID: PMC4335096,,,,Humans; Computer Simulation; *Medication Adherence; *Self Care; *Telemedicine; *Text Messaging; 1; Monte Carlo; 420,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, W2E93QM8,journalArticle,2014,"Bishai, David; Paina, Ligia; Li, Qingfeng; Peters, David H.; Hyder, Adnan A.",Advancing the application of systems thinking in health: why cure crowds out prevention.,Health research policy and systems,,1478-4505 1478-4505,10.1186/1478-4505-12-28,,"INTRODUCTION: This paper presents a system dynamics computer simulation model to illustrate unintended consequences of apparently rational allocations to curative and preventive services. METHODS: A modeled population is subject to only two diseases. Disease A is a curable disease that can be shortened by curative care. Disease B is an instantly fatal but preventable disease. Curative care workers are financed by public spending and private fees to cure disease A. Non-personal, preventive services are delivered by public health workers supported solely by public spending to prevent disease B. Each type of worker tries to tilt the balance of government spending towards their interests. Their influence on the government is proportional to their accumulated revenue. RESULTS: The model demonstrates effects on lost disability-adjusted life years and costs over the course of several epidemics of each disease. Policy interventions are tested including: i) an outside donor rationally donates extra money to each type of disease precisely in proportion to the size of epidemics of each disease; ii) lobbying is eliminated; iii) fees for personal health services are eliminated; iv) the government continually rebalances the funding for prevention by ring-fencing it to protect it from lobbying.The model exhibits a ""spend more get less"" equilibrium in which higher revenue by the curative sector is used to influence government allocations away from prevention towards cure. Spending more on curing disease A leads paradoxically to a higher overall disease burden of unprevented cases of disease B. This paradoxical behavior of the model can be stopped by eliminating lobbying, eliminating fees for curative services, and ring-fencing public health funding. CONCLUSIONS: We have created an artificial system as a laboratory to gain insights about the trade-offs between curative and preventive health allocations, and the effect of indicative policy interventions. The underlying dynamics of this artificial system resemble features of modern health systems where a self-perpetuating industry has grown up around disease-specific curative programs like HIV/AIDS or malaria. The model shows how the growth of curative care services can crowd both fiscal and policy space for the practice of population level prevention work, requiring dramatic interventions to overcome these trends.",16/06/2014,13/11/2018 10:47,14/04/2020 08:34,,28,,,12,,Health Res Policy Syst,,,,,,,,eng,,,,,,,PMID: 24935344 PMCID: PMC4073815,,,,"Humans; Quality-Adjusted Life Years; Health Care Costs; Computer Simulation; Health Expenditures; Models, Economic; Financing, Organized; Health Policy/economics; Preventive Medicine/*economics; Delivery of Health Care/economics; Health Care Rationing/economics; Health Resources/economics/supply & distribution; Lobbying; Therapeutics/*economics; 1; Human; Models; Health Resource Utilization; Statistical; Preventive Health Care – Economics; Financing; Health Policy – Economics; Health Resource Allocation – Economics; Health Resource Utilization – Economics; Organized; Therapeutics – Economics; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KHYI4CVD,journalArticle,2014,"Kapogiannis, Bill G.; Legins, Ken E.; Chandan, Upjeet; Lee, Sonia",Evidence-based programming for adolescent HIV prevention and care: operational research to inform best practices.,Journal of acquired immune deficiency syndromes (1999),,1944-7884 1525-4135,10.1097/QAI.0000000000000177,,"BACKGROUND: Globally, a staggering number of adolescents, approximately 2.1 million, were estimated to be living with HIV in 2012. Unique developmental, psychosocial, and environmental considerations make them particularly vulnerable to HIV acquisition and argue for a comprehensive response to address this burgeoning problem. METHODS: This article explores the current state of the science of HIV prevention, treatment, and care for adolescents and identifies opportunities to address knowledge gaps and improve health outcomes for this age group. RESULTS: Over the past decade, several important milestones have been achieved in HIV prevention and care among adults, and despite evidence that adherence to care and medications among affected adolescents is significantly compromised, critical research among adolescents and young adults substantially lags behind. Operational research, in particular, is crucial to understanding how to use effective services and interventions for HIV prevention and care safely and effectively for adolescents who are in dire need. CONCLUSIONS: Operational research among adolescent populations affected by HIV is critically needed to close the knowledge and investment gaps, and scale-up efforts for HIV prevention, treatment, care, and support for this vulnerable age group.",01/07/2014,13/11/2018 10:47,14/04/2020 08:34,,S228-235,,,66 Suppl 2,,J Acquir Immune Defic Syndr,,,,,,,,eng,,,,,,,PMID: 24918600,,,,Humans; Health Services Accessibility; Young Adult; Child; Adolescent; Research Design; HIV Infections/*prevention & control; Primary Prevention; Adolescent Behavior; Counseling; Evidence-Based Practice/*methods/*organization & administration; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 47GFY6Y7,journalArticle,2015,"Tate, Wendy R.; Skrepnek, Grant H.",Quality-adjusted time without symptoms or toxicity (Q-TWiST): patient-reported outcome or mathematical model? A systematic review in cancer.,Psycho-oncology,,1099-1611 1057-9249,10.1002/pon.3595,,"OBJECTIVE: Successful cancer treatment is defined as an increase in overall survival and/or progression-free survival. Despite their importance, these metrics omit patient quality of life. Quality-adjusted time without symptoms or toxicity (Q-TWiST) was developed to adjust survival gained, accounting for quality of life. The purpose of this systematic review was to assess the methods reported in cancer literature to determine Q-TWiST values and how these are currently translated to the clinic. METHODS: The Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines were used to conduct a systematic review of studies indexed on MEDLINE and Web of Science through April 2013. Cancer studies that measured Q-TWiST either as a primary outcome or retrospectively and determined utility coefficients from a patient population were identified, and their methods reviewed to determine how the utility coefficient was calculated. Additionally, other relevant factors such as definitions of health states and significant findings were collected and summarized. RESULTS: Out of 284 studies, 11 were identified that calculated patient-defined utility coefficients. Several methods to determine utility coefficients were reported, and multiple definitions of health state toxicity were applied. Of these studies, seven reported significant differences (p < 0.05) in quality-adjusted survival. No studies, however, directly discussed the clinical relevance of their findings. CONCLUSIONS: Currently, Q-TWiST is utilized as a mathematical theory rather than a clinical tool. Standardization of terminology plus reliability and validity testing of determining both utility coefficients and time frame definitions must be performed before Q-TWiST can become clinically useful to physicians and patients alike for making treatment decisions.",2015-03,13/11/2018 10:47,14/04/2020 08:35,,253-261,,3,24,,Psychooncology,,,,,,,,eng,"Copyright (c) 2014 John Wiley & Sons, Ltd.",,,,,,PMID: 24917078,,,,"Humans; Quality-Adjusted Life Years; Reproducibility of Results; *Quality-Adjusted Life Years; Quality of Life; Models, Theoretical; *Patient Outcome Assessment; *Surveys and Questionnaires; Antineoplastic Combined Chemotherapy Protocols/adverse effects/*therapeutic use; cancer; Neoplasms/*drug therapy; oncology; patient-reported outcome; Q-TWiST; quality of life; Human; Models; Theoretical; Questionnaires; Outcome Assessment; Evidence-Based; Professional Practice; Systematic Review; Medline; Antineoplastic Agents; Combined – Adverse Effects; Combined – Therapeutic Use; Neoplasms – Drug Therapy; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QB5492FQ,journalArticle,2016,"Dieckmann, Peter; Clemmensen, Marianne Hald; Sorensen, Trine Kart; Kunstek, Pina; Hellebek, Annemarie",Identifying Facilitators and Barriers for Patient Safety in a Medicine Label Design System Using Patient Simulation and Interviews.,Journal of patient safety,,1549-8425 1549-8417,10.1097/PTS.0000000000000109,,"OBJECTIVES: Medicine label design plays an important role in improving patient safety. This study aimed at identifying facilitators and barriers in a medicine label system to prevent medication errors in clinical use by health care professionals. METHODS: The study design is qualitative and exploratory, with a convenience sample of 10 nurses and 10 physicians from different acute care specialties working in hospitals in the Capital Region of Denmark. In 2 patient simulation scenarios and a sorting task, the participants selected the medicines from a range of ampules, vials, and infusion bags. After each scenario and in the end of the study, the participants were interviewed. Notes were validated with the participants, and content was analyzed. RESULTS: The label design benefited from the standardized construction of the labels, the clear layout and font, and some warning signs. The complexity of the system and some inconsistencies (different meaning of colors) posed challenges, when considered with the actual application context, in which there is little time to get familiar with the design features. CONCLUSIONS: For optimizing medicine labels and obtaining the full benefit of label design features on patient safety, it is necessary to consider the context in which they are used.",2016-12,13/11/2018 10:47,14/04/2020 08:34,,210-222,,4,12,,J Patient Saf,,,,,,,,eng,,,,,,,PMID: 24832588,,,,Humans; Adult; Female; Male; Middle Aged; Patient Safety; *Patient Safety; Cognition; Nurses; Attitude of Health Personnel; Hospitals; Denmark; Patient Simulation; *Drug Labeling/standards; *Medication Errors/prevention & control; *Nurses; *Physicians; Problem Solving; Safety Management/*methods; Descriptive Statistics; Human; Qualitative Studies; Content Analysis; Convenience Sample; Data Analysis Software; Questionnaires; Semi-Structured Interview; Funding Source; Drug Labeling – Methods; Exploratory Research; Health Services Accessibility – Evaluation; Medication Errors – Prevention and Control; Physicians; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, X6SXAVEG,journalArticle,2014,"Maglio, Paul P.; Sepulveda, Martin-J.; Mabry, Patricia L.",Mainstreaming modeling and simulation to accelerate public health innovation.,American journal of public health,,1541-0048 0090-0036,10.2105/AJPH.2014.301873,,"Dynamic modeling and simulation are systems science tools that examine behaviors and outcomes resulting from interactions among multiple system components over time. Although there are excellent examples of their application, they have not been adopted as mainstream tools in population health planning and policymaking. Impediments to their use include the legacy and ease of use of statistical approaches that produce estimates with confidence intervals, the difficulty of multidisciplinary collaboration for modeling and simulation, systems scientists' inability to communicate effectively the added value of the tools, and low funding for population health systems science. Proposed remedies include aggregation of diverse data sets, systems science training for public health and other health professionals, changing research incentives toward collaboration, and increased funding for population health systems science projects.",2014-07,13/11/2018 10:47,14/04/2020 08:34,,1181-1186,,7,104,,Am J Public Health,,,,,,,,eng,,,,,,,PMID: 24832426 PMCID: PMC4056212,,,,"Humans; Research; *Public Health; *Computer Simulation; Communication; *Models, Theoretical; *Research Design; Policy Making; System dynamics; Cooperative Behavior; Systems Theory; *Systems Theory; Obesity/prevention & control; Health Behavior; Health Planning; Diffusion of Innovation; 1; Computer Simulation – Utilization; Data Analysis; Interdisciplinary; Contingency Management; Obesity – Etiology; Obesity – Prevention and Control; Research Personnel; Research Support; Skill Acquisition; Statistical – Methods; 210",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, AXPECGIS,journalArticle,2014,"Ballangrud, Randi; Hall-Lord, Marie Louise; Persenius, Mona; Hedelin, Birgitta",Intensive care nurses' perceptions of simulation-based team training for building patient safety in intensive care: a descriptive qualitative study.,Intensive & critical care nursing,,1532-4036 0964-3397,10.1016/j.iccn.2014.03.002,,"OBJECTIVES: To describe intensive care nurses' perceptions of simulation-based team training for building patient safety in intensive care. BACKGROUND: Failures in team processes are found to be contributory factors to incidents in an intensive care environment. Simulation-based training is recommended as a method to make health-care personnel aware of the importance of team working and to improve their competencies. DESIGN: The study uses a qualitative descriptive design. METHODS: Individual qualitative interviews were conducted with 18 intensive care nurses from May to December 2009, all of which had attended a simulation-based team training programme. The interviews were analysed by qualitative content analysis. RESULTS: One main category emerged to illuminate the intensive care nurse perception: ""training increases awareness of clinical practice and acknowledges the importance of structured work in teams"". Three generic categories were found: ""realistic training contributes to safe care"", ""reflection and openness motivates learning"" and ""finding a common understanding of team performance"". CONCLUSIONS: Simulation-based team training makes intensive care nurses more prepared to care for severely ill patients. Team training creates a common understanding of how to work in teams with regard to patient safety.",2014-08,13/11/2018 10:47,14/04/2020 08:34,,179-187,,4,30,,Intensive Crit Care Nurs,,,,,,,,eng,Copyright (c) 2014 Elsevier Ltd. All rights reserved.,,,,,,PMID: 24731413,,,,"Humans; Staff Development; *Simulation Training; Adult; Female; Male; Middle Aged; Patient Safety/*standards; Patient Safety; Qualitative Research; Communication; *Attitude of Health Personnel; Motivation; Patient safety; Norway; Simulation-based training; Age Factors; Critical Care Nursing/*education/methods; Critical Care/methods/*psychology; Intensive care; Nursing; Nursing Staff, Hospital/*education/*psychology; Nursing, Team/methods; Team performance; Human; Descriptive Research; Qualitative Studies; Content Analysis; Middle Age; Simulations; Coding; Perception; Funding Source; Interviews; Registered Nurses; Teamwork – Education; Critical Care Nursing – Education; Nurse Attitudes; Reflection; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HZGEIICP,journalArticle,2014,"Klipfel, Janee M.; Carolan, Bridget J.; Brytowski, Nathan; Mitchell, Catherine A.; Gettman, Matthew T.; Jacobson, Therese M.",Patient safety improvement through in situ simulation interdisciplinary team training.,Urologic nursing,,1053-816X 1053-816X,,,"In situ simulation is an education strategy that promotes patient safety and enhances interdisciplinary teamwork. When a patient is experiencing an acute health status change or a rapidly emerging condition, teamwork is necessary to adequately and appropriately provide treatment. A unit-based quality improvement project was designed to enhance these skills. In situ simulation was used as the training venue for nurses and physicians to practice the techniques recommended in the evidence-based team-building model, TeamSTEPPS.",2014-02,13/11/2018 10:47,14/04/2020 08:34,,39-46,,1,34,,Urol Nurs,,,,,,,,eng,,,,,,,PMID: 24716380,,,,"Humans; Program Evaluation; Male; Patient Safety/*standards; *Quality Improvement; Aged; Communication; Quality Improvement; Inpatients; Education, Nursing, Continuing; Inservice Training/*methods; Nephrology Nursing/*standards; Patient Care Team/*standards; Urinary Bladder Neoplasms/*nursing/therapy; Education; Postoperative Care; Human; Descriptive Research; Qualitative Studies; Scales; Simulations; Patient Safety – Education; Questionnaires; Conceptual Framework; Bladder Neoplasms – Surgery; Continuing (Credit); Documentation; Interdisciplinary; Interns and Residents; Patient Assessment; Patient Care Conferences; Quality of Care Research; Registered Nurses; Respect; Surveys; Teaching Materials; Teamwork – Education; Urologic Nursing; Videorecording; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UFYX5NE3,journalArticle,2014,"Cummings, L.",Coping with uncertainty in public health: the use of heuristics.,Public health,,1476-5616 0033-3506,10.1016/j.puhe.2014.01.012,,,2014-04,13/11/2018 10:47,14/04/2020 08:34,,391-394,,4,128,,Public Health,,,,,,,,eng,,,,,,,PMID: 24602855,,,,"Humans; Adult; Female; Male; Middle Aged; Young Adult; *Public Health; Aged; Risk Assessment; Adolescent; *Uncertainty; *Adaptation, Psychological; 1; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BDWY8ZE7,journalArticle,2014,"Smith, Brendan T.; Smith, Peter M.; Harper, Sam; Manuel, Douglas G.; Mustard, Cameron A.",Reducing social inequalities in health: the role of simulation modelling in chronic disease epidemiology to evaluate the impact of population health interventions.,Journal of epidemiology and community health,,1470-2738 0143-005X,10.1136/jech-2013-202756,,"Reducing health inequalities has become a major public health priority internationally. However, how best to achieve this goal is not well understood. Population health intervention research has the potential to address some of this knowledge gap. This review argues that simulation studies can produce unique evidence to build the population health intervention research evidence base on reducing social inequalities in health. To this effect, the advantages of using simulation models over other population health intervention research methods are discussed. Key questions regarding the potential challenges of developing simulation models to investigate population health intervention research on reducing social inequalities in health and the types of population health intervention research questions that can be answered using this methodology are reviewed. We use the example of social inequalities in coronary heart disease to illustrate how simulation models can elucidate the effectiveness of a number of 'what-if' counterfactual population health interventions on reducing social inequalities in coronary heart disease. Simulation models are a flexible, cost-effective, evidence-based research method with the capacity to inform public health policy-makers regarding the implementation of population health interventions to reduce social inequalities in health.",2014-04,13/11/2018 10:47,14/04/2020 08:34,,384-389,,4,68,,J Epidemiol Community Health,,,,,,,,eng,,,,,,,PMID: 24363409 PMCID: PMC3963537,,,,Humans; Health Promotion; Healthcare Disparities; Computer Simulation; Public Health; Modelling; Health Status Disparities; *Chronic Disease; Social Class; *Coronary Disease; *Health Status Disparities; *Socioeconomic Factors; Epidemiological methods; Public Health Policy; Social Inequalities; 1; Models; Theoretical; Study Design; Cardiovascular Diseases – Prevention and Control; Epidemiological Research; Cardiovascular Risk Factors; Experimental Studies; Research Methodology; ******To read; X,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, J42XBPG2,journalArticle,2014,"Stanley, Mary Jo; Rojas, Deb",Teaching undergraduate nursing students about environmental health: addressing public health issues through simulation.,The Journal of nursing education,,1938-2421 0148-4834,10.3928/01484834-20131218-04,,"Schools of nursing are challenged to find clinical placements in public health settings. Use of simulation can address situations unique to public health, with attention to specific concerns, such as environmental health. Environmental health is an integral part of public health nursing and is a standard of professional practice. Current simulations focus on acute care situations, offering limited scenarios with a public health perspective and excluding environmental health. This study's simulation scenario was created to enhance nursing students' understanding of public health concepts within an environmental health context. Outcomes from the simulation include the need for integration of environmental issues in public health teaching. Students stated that this scenario provided a broader understanding of the environmental influences that can affect the client's and family's health. This scenario fills a void in simulation content, while providing an interactive teaching and learning strategy to help students to apply knowledge to practice.",01/01/2014,13/11/2018 10:47,14/04/2020 08:35,,48-51,,1,53,,J Nurs Educ,,,,,,,,eng,"Copyright 2014, SLACK Incorporated.",,,,,,PMID: 24328251,,,,"Humans; Female; Learning; Nursing Education Research; Nursing Evaluation Research; *Patient Simulation; Child; Public Health; Education, Nursing, Baccalaureate/*methods; Environmental Health/*education; Public Health Nursing/*education; Students; Nursing Methodology Research; Patient Simulation; Nursing; Education; Students, Nursing/psychology; Teaching/*methods; Human; Outcomes of Education; Models; Asthma – Therapy – In Infancy and Childhood; Case Studies; Environmental Health; Structural; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2SEE6AYG,journalArticle,2015,"Rutberg, Matthew Harris; Wenczel, Sharon; Devaney, John; Goldlust, Eric Jonathan; Day, Theodore Eugene",Incorporating discrete event simulation into quality improvement efforts in health care systems.,American journal of medical quality : the official journal of the American College of Medical Quality,,1555-824X 1062-8606,10.1177/1062860613512863,,"Quality improvement (QI) efforts are an indispensable aspect of health care delivery, particularly in an environment of increasing financial and regulatory pressures. The ability to test predictions of proposed changes to flow, policy, staffing, and other process-level changes using discrete event simulation (DES) has shown significant promise and is well reported in the literature. This article describes how to incorporate DES into QI departments and programs in order to support QI efforts, develop high-fidelity simulation models, conduct experiments, make recommendations, and support adoption of results. The authors describe how DES-enabled QI teams can partner with clinical services and administration to plan, conduct, and sustain QI investigations.",2015-02,13/11/2018 10:47,14/04/2020 08:34,,31-35,,1,30,,Am J Med Qual,,,,,,,,eng,(c) 2013 by the American College of Medical Quality.,,,,,,PMID: 24324280,,,,"Humans; Quality Indicators, Health Care; *Computer Simulation; Quality Improvement/*organization & administration; quality improvement; Quality Assurance, Health Care/*organization & administration; *Problem Solving; discrete event simulation; health care delivery; performance improvement; 1; Discrete event; 320",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, AALL4JZN,journalArticle,2014,"Lounsbury, David W.; Hirsch, Gary B.; Vega, Chawntel; Schwartz, Carolyn E.",Understanding social forces involved in diabetes outcomes: a systems science approach to quality-of-life research.,"Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation",,1573-2649 0962-9343,10.1007/s11136-013-0532-4,,"PURPOSE: The field of quality-of-life (QOL) research would benefit from learning about and integrating systems science approaches that model how social forces interact dynamically with health and affect the course of chronic illnesses. Our purpose is to describe the systems science mindset and to illustrate the utility of a system dynamics approach to promoting QOL research in chronic disease, using diabetes as an example. METHODS: We build a series of causal loop diagrams incrementally, introducing new variables and their dynamic relationships at each stage. RESULTS: These causal loop diagrams demonstrate how a common set of relationships among these variables can generate different disease and QOL trajectories for people with diabetes and also lead to a consideration of non-clinical (psychosocial and behavioral) factors that can have implications for program design and policy formulation. CONCLUSIONS: The policy implications of the causal loop diagrams are discussed, and empirical next steps to validate the diagrams and quantify the relationships are described.",2014-04,13/11/2018 10:47,14/04/2020 08:34,,959-969,,3,23,,Qual Life Res,,,,,,,,eng,,,,,,,PMID: 24062243,,,,"*Health Policy; Humans; Health Policy; Health Services Accessibility; Healthcare Disparities; Risk Factors; Quality of Life; System dynamics; *Quality of Life; Health Knowledge, Attitudes, Practice; Interpersonal Relations; Adaptation, Psychological; Systems Theory; *Life Style; Diabetes Mellitus/*psychology/therapy; Outcome Assessment (Health Care)/*methods/standards; Terminology as Topic; Life Style; 1; Psychological; Adaptation; Attitude to Health; Diabetes Mellitus – Psychosocial Factors; Diabetes Mellitus – Therapy; Nomenclature; Outcome Assessment – Methods; Outcome Assessment – Standards; 410",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, E59F72D8,journalArticle,2013,"Black, Maureen M.; Hager, Erin R.",Commentary: Pediatric obesity: systems science strategies for prevention.,Journal of pediatric psychology,,1465-735X 0146-8693,10.1093/jpepsy/jst071,,"OBJECTIVES: Pediatric obesity is a major public health problem that undermines the physical and mental health of children and increases their risk for adult obesity and other chronic illnesses. Although health care providers, including pediatric psychologists, have implemented prevention programs, effects have been minimal, with no solid evidence of sustainable programs. METHODS: A systems science framework that incorporates the multiple interacting factors that influence pediatric obesity may be useful in guiding prevention. RESULTS: The National Prevention Strategy provides recommendations that can be incorporated into systems science designs, including (1) Healthy and Safe Environments, (2) Clinical and Community Preventive Services, (3) Empowering People, and (4) Elimination of Health Disparities. In addition, our recommendation is that future obesity prevention programs target early in life (pre-pregnancy through toddlerhood) and use multilevel multidisciplinary designs. CONCLUSIONS: The benefits of preventing pediatric obesity extend from the health and well-being of individual children to the economic security of the nation.",2013-10,13/11/2018 10:47,14/04/2020 08:34,,1044-1050,,9,38,,J Pediatr Psychol,,,,,,,,eng,,,,,,,PMID: 24013965 PMCID: PMC3888301,,,,Humans; United States; Child; Systems Analysis; Health Status Disparities; Health Priorities; Residence Characteristics; Obesity/etiology/*prevention & control/psychology; Power (Psychology); Health and Welfare Planning; Obesity – Etiology; Obesity – Prevention and Control; Obesity – Psychosocial Factors; Power; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YK33ICCI,journalArticle,2013,"Sorensen, Jette Led; Van der Vleuten, Cees; Lindschou, Jane; Gluud, Christian; Ostergaard, Doris; LeBlanc, Vicki; Johansen, Marianne; Ekelund, Kim; Albrechtsen, Charlotte Krebs; Pedersen, Berit Woetman; Kjaergaard, Hanne; Weikop, Pia; Ottesen, Bent","'In situ simulation' versus 'off site simulation' in obstetric emergencies and their effect on knowledge, safety attitudes, team performance, stress, and motivation: study protocol for a randomized controlled trial.",Trials,,1745-6215 1745-6215,10.1186/1745-6215-14-220,,"BACKGROUND: Unexpected obstetric emergencies threaten the safety of pregnant women. As emergencies are rare, they are difficult to learn. Therefore, simulation-based medical education (SBME) seems relevant. In non-systematic reviews on SBME, medical simulation has been suggested to be associated with improved learner outcomes. However, many questions on how SBME can be optimized remain unanswered. One unresolved issue is how 'in situ simulation' (ISS) versus 'off site simulation' (OSS) impact learning. ISS means simulation-based training in the actual patient care unit (in other words, the labor room and operating room). OSS means training in facilities away from the actual patient care unit, either at a simulation centre or in hospital rooms that have been set up for this purpose. METHODS AND DESIGN: The objective of this randomized trial is to study the effect of ISS versus OSS on individual learning outcome, safety attitude, motivation, stress, and team performance amongst multi-professional obstetric-anesthesia teams.The trial is a single-centre randomized superiority trial including 100 participants. The inclusion criteria were health-care professionals employed at the department of obstetrics or anesthesia at Rigshospitalet, Copenhagen, who were working on shifts and gave written informed consent. Exclusion criteria were managers with staff responsibilities, and staff who were actively taking part in preparation of the trial. The same obstetric multi-professional training was conducted in the two simulation settings. The experimental group was exposed to training in the ISS setting, and the control group in the OSS setting. The primary outcome is the individual score on a knowledge test. Exploratory outcomes are individual scores on a safety attitudes questionnaire, a stress inventory, salivary cortisol levels, an intrinsic motivation inventory, results from a questionnaire evaluating perceptions of the simulation and suggested changes needed in the organization, a team-based score on video-assessed team performance and on selected clinical performance. DISCUSSION: The perspective is to provide new knowledge on contextual effects of different simulation settings. TRIAL REGISTRATION: ClincialTrials.gov NCT01792674.",17/07/2013,13/11/2018 10:47,14/04/2020 08:35,,220,,,14,,Trials,,,,,,,,eng,,,,,,,PMID: 23870501 PMCID: PMC3716971,,,,"Humans; Surveys and Questionnaires; Clinical Competence; Female; *Patient Simulation; Interprofessional Relations; Risk Factors; Risk Assessment; *Computer Simulation; Computer Simulation; Emergencies; Pregnancy; *Research Design; Interdisciplinary Communication; *Attitude of Health Personnel; Motivation; Surgery; Group Processes; Education, Medical, Continuing/*methods; *Health Knowledge, Attitudes, Practice; *Workplace; Attitude of Health Personnel; Cooperative Behavior; Denmark; Patient Simulation; Task Performance and Analysis; Education; *Manikins; *Motivation; *Patient Care Team/organization & administration; Obstetric Surgical Procedures/adverse effects/*education; Stress, Psychological/*etiology; Video Recording; Stress; Human; Models; Questionnaires; Medical; Videorecording; Study Design; Attitude to Health; Anatomic; Work Environment; Continuing; Multidisciplinary Care Team – Administration; Obstetrical – Adverse Effects; Obstetrical – Education; Psychological – Etiology; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9JDJXHHL,journalArticle,2014,"Carayon, Pascale; Wetterneck, Tosha B.; Rivera-Rodriguez, A. Joy; Hundt, Ann Schoofs; Hoonakker, Peter; Holden, Richard; Gurses, Ayse P.",Human factors systems approach to healthcare quality and patient safety.,Applied ergonomics,,1872-9126 0003-6870,10.1016/j.apergo.2013.04.023,,Human factors systems approaches are critical for improving healthcare quality and patient safety. The SEIPS (Systems Engineering Initiative for Patient Safety) model of work system and patient safety is a human factors systems approach that has been successfully applied in healthcare research and practice. Several research and practical applications of the SEIPS model are described. Important implications of the SEIPS model for healthcare system and process redesign are highlighted. Principles for redesigning healthcare systems using the SEIPS model are described. Balancing the work system and encouraging the active and adaptive role of workers are key principles for improving healthcare quality and patient safety.,2014-01,13/11/2018 10:47,14/04/2020 08:34,,14-25,,1,45,,Appl Ergon,,,,,,,,eng,Copyright (c) 2013 Elsevier Ltd and The Ergonomics Society. All rights reserved.,,,,,,PMID: 23845724 PMCID: PMC3795965,,,,"Humans; *Quality of Health Care; Quality of Health Care; Outcome and Process Assessment (Health Care); Patient Safety; Patient-Centered Care; Models, Theoretical; *Patient Safety; SEIPS model; Patient safety; Systems Integration; Ergonomics; *Ergonomics; Balanced work system; Healthcare; Healthcare team; Macroergonomics; Patient-centered care; Sociotechnical system; Models; Theoretical; Patient Centered Care; Outcomes (Health Care); 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9RXT3PL4,journalArticle,2013,"Tupper, Judith B.; Pearson, Karen B.; Meinersmann, Krista M.; Dvorak, Jean",Little shop of errors: an innovative simulation patient safety workshop for community health care professionals.,Journal of continuing education in nursing,,0022-0124 0022-0124,10.3928/00220124-20130501-63,,"Continuing education for health care workers is an important mechanism for maintaining patient safety and high-quality health care. Interdisciplinary continuing education that incorporates simulation can be an effective teaching strategy for improving patient safety. Health care professionals who attended a recent Patient Safety Academy had the opportunity to experience firsthand a simulated situation that included many potential patient safety errors. This high-fidelity activity combined the best practice components of a simulation and a collaborative experience that promoted interdisciplinary communication and learning. Participants were challenged to see, learn, and experience ""ah-ha"" moments of insight as a basis for error reduction and quality improvement. This innovative interdisciplinary educational training method can be offered in place of traditional lecture or online instruction in any facility, hospital, nursing home, or community care setting.",2013-06,13/11/2018 10:47,14/04/2020 08:35,,274-277,,6,44,,J Contin Educ Nurs,,,,,,,,eng,"Copyright 2013, SLACK Incorporated.",,,,,,PMID: 23654294,,,,"Humans; Program Evaluation; Nursing Evaluation Research; Safety Management/*methods; Nursing; Community Health Nursing/*education; Education; *Manikins; Education, Nursing, Continuing/*organization & administration; Program Implementation; Simulations; Schools; Continuing – Maine; Health Care Errors; Health Personnel – Education – Maine; Learning Laboratories; Maine; Patient Safety – Education – Maine; Program Planning; Seminars and Workshops – Maine; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QILQEMDF,journalArticle,2013,"Aslanyan, Garry; Chauvin, James; Edwards, Nancy; King, Margaret; Raine, Kim; Taylor, Gregory",Are we close to systems thinking in public health in Canada?,Canadian journal of public health = Revue canadienne de sante publique,,1920-7476 0008-4263,,,,25/02/2013,13/11/2018 10:47,14/04/2020 08:34,,e183,,2,104,,Can J Public Health,,,,,,,,eng,,,,,,,PMID: 23618215,,,,*Health Care Reform; Humans; *Public Health Administration; 00; ******To read; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7SBNGM74,journalArticle,2013,"Schmidt, Eric; Goldhaber-Fiebert, Sara N.; Ho, Lawrence A.; McDonald, Kathryn M.",Simulation exercises as a patient safety strategy: a systematic review.,Annals of internal medicine,,1539-3704 0003-4819,10.7326/0003-4819-158-5-201303051-00010,,"Simulation is a versatile technique used in a variety of health care settings for a variety of purposes, but the extent to which simulation may improve patient safety remains unknown. This systematic review examined evidence on the effects of simulation techniques on patient safety outcomes. PubMed and the Cochrane Library were searched from their beginning to 31 October 2012 to identify relevant studies. A single reviewer screened 913 abstracts and selected and abstracted data from 38 studies that reported outcomes during care of real patients after patient-, team-, or system-level simulation interventions. Studies varied widely in the quality of methodological design and description of simulation activities, but in general, simulation interventions improved the technical performance of individual clinicians and teams during critical events and complex procedures. Limited evidence suggested improvements in patient outcomes attributable to simulation exercises at the health system level. Future studies would benefit from standardized reporting of simulation components and identification of robust patient safety targets.",05/03/2013,13/11/2018 10:47,14/04/2020 08:35,,426-432,,5 Pt 2,158,,Ann Intern Med,,,,,,,,eng,,,,,,,PMID: 23460100,,,,Humans; Outcome Assessment (Health Care); Cost-Benefit Analysis; Clinical Competence; *Patient Simulation; Patient Care Team; Costs and Cost Analysis; Patient Simulation; Safety Management/economics/*methods; *Patient Safety/standards; Human; Cost Benefit Analysis; Outcome Assessment; PubMed; Systematic Review; Cochrane Library; Multidisciplinary Care Team; Patient Safety – Standards; Safety – Economics; Safety – Methods; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, AKH5VLHY,journalArticle,2013,"Wheeler, Derek S.; Geis, Gary; Mack, Elizabeth H.; LeMaster, Tom; Patterson, Mary D.",High-reliability emergency response teams in the hospital: improving quality and safety using in situ simulation training.,BMJ quality & safety,,2044-5423 2044-5415,10.1136/bmjqs-2012-000931,,"INTRODUCTION: In situ simulation training is a team-based training technique conducted on actual patient care units using equipment and resources from that unit, and involving actual members of the healthcare team. We describe our experience with in situ simulation training in a major children's medical centre. MATERIALS AND METHODS: In situ simulations were conducted using standardised scenarios approximately twice per month on inpatient hospital units on a rotating basis. Simulations were scheduled so that each unit participated in at least two in situ simulations per year. Simulations were conducted on a revolving schedule alternating on the day and night shifts and were unannounced. Scenarios were preselected to maximise the educational experience, and frequently involved clinical deterioration to cardiopulmonary arrest. RESULTS: We performed 64 of the scheduled 112 (57%) in situ simulations on all shifts and all units over 21 months. We identified 134 latent safety threats and knowledge gaps during these in situ simulations, which we categorised as medication, equipment, and/or resource/system threats. Identification of these errors resulted in modification of systems to reduce the risk of error. In situ simulations also provided a method to reinforce teamwork behaviours, such as the use of assertive statements, role clarity, performance of frequent updating, development of a shared mental model, performance of independent double checks of high-risk medicines, and overcoming authority gradients between team members. Participants stated that the training programme was effective and did not disrupt patient care. CONCLUSIONS: In situ simulations can identify latent safety threats, identify knowledge gaps, and reinforce teamwork behaviours when used as part of an organisation-wide safety programme.",2013-06,13/11/2018 10:47,14/04/2020 08:35,,507-514,,6,22,,BMJ Qual Saf,,,,,,,,eng,,,,,,,PMID: 23457361,,,,"Humans; *Patient Simulation; Medical Errors/prevention & control; Patient Safety; Reproducibility of Results; Quality Assurance, Health Care/*methods; Professional Role; Child; Appointments and Schedules; Communication; Emergencies; Quality Improvement; Prospective Studies; Inpatients; *Safety Management; Hospitals; Simulation; Intensive Care Units; *Emergency Responders; *Patient Care Team/statistics & numerical data; Coronary Care Units/organization & administration; Crew Resource Management; Hospitals, Pediatric; Inservice Training/*standards; Intensive Care Units, Pediatric/organization & administration; Ohio; Team Training; Equipment Failure; Descriptive Statistics; Human; Vignettes; Funding Source; Assertiveness; Authority; Communication Skills; Coronary Care Units – Utilization; Critically Ill Patients; Employee Attitudes; Medication Errors; Operating Rooms – Utilization; Pediatric – Ohio; Pediatric – Utilization; Professional Knowledge; Reaction Time; Simulations – Utilization – Ohio; Work Environment; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UM9RHQUL,journalArticle,2013,"Siegler, Aaron J.; Mbwambo, Jessie K.; DiClemente, Ralph J.",Applying the Dynamic Social Systems Model to HIV prevention in a rural African context: the Maasai and the esoto dance.,Health education & behavior : the official publication of the Society for Public Health Education,,1552-6127 1090-1981,10.1177/1090198112474004,,"This study applied the Dynamic Social Systems Model (DSSM) to the issue of HIV risk among the Maasai tribe of Tanzania, using data from a cross-sectional, cluster survey among 370 randomly selected participants from Ngorongoro and Siha Districts. A culturally appropriate survey instrument was developed to explore traditions reportedly coadunate with sexual partnership, including ""wife sharing"", fertility rituals, and various traditional dances. One dance, esoto, accounted for more than two thirds of participants' lifetime sexual partners (n = 10.5). The DSSM, combining structural and systems theories, was applied to systematize complex multilevel factors regarding esoto practice. Participants reported multifaceted beliefs regarding esoto; a majority viewed the dance as exciting and essential, yet most men feared social stigma and three quarters of women had experienced physical punishment for nonattendance. In multivariate logistic regression, esoto attendance was predicted by female gender (adjusted odds ratio [AOR] = 4.67, 95% confidence interval [CI] = 1.6-13.2), higher positive beliefs regarding esoto (AOR = 2.84, 95% CI = 1.9-4.2), and Maasai life cycle events (AOR = 0.06, 95% CI = 0.01-0.47). The DSSM proved useful for characterizing esoto and for revealing feedback loops that maintain esoto, thus indicating avenues for future interventions.",2013-12,13/11/2018 10:47,14/04/2020 08:35,,683-693,,6,40,,Health Educ Behav,,,,,,,,eng,,,,,,,PMID: 23372030 PMCID: PMC3830632,,,,"Humans; Adult; Female; Male; *Models, Theoretical; Cross-Sectional Studies; Health Knowledge, Attitudes, Practice; Logistic Models; HIV/AIDS; HIV Infections/*prevention & control; Confidence Intervals; Odds Ratio; *Cultural Characteristics; *Dancing; *Rural Population; *Sexual Behavior; behavioral theories; Condoms; international health; measurement issues; Population Groups; sex behavior; Tanzania/ethnology; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, W5T38JBH,journalArticle,2013,"Shear, Torin D.; Greenberg, Steven B.; Tokarczyk, Arthur",Does training with human patient simulation translate to improved patient safety and outcome?,Current opinion in anaesthesiology,,1473-6500 0952-7907,10.1097/ACO.0b013e32835dc0af,,"PURPOSE OF REVIEW: In this review, we evaluate several articles in an attempt to qualify the effect of human patient simulation in anaesthesia on patient outcome. The recognition of medical error as a significant cause of patient morbidity and mortality has sparked an increased focus on improving healthcare quality and patient safety. Simulation in anaesthesia is a potential tool to help achieve this goal by allowing anaesthesia providers to learn, practice and perfect their craft without a potential harm to patients. It has gained growing traction in the field and is recently a required element in the American Board of Anesthesiology's Maintenance of Certification in Anesthesia programme. RECENT FINDINGS: Very few studies have evaluated the effect of simulation on patient outcome. To date, one study has demonstrated improved individual clinical performance in anaesthesia after simulation training. Research suggests that simulation-based team training can reduce patient mortality and improve the quality of care as measured by surgical quality improvement measures. Simulation may improve healthcare systems by serving as a tool to detect latent error and drive process improvement. SUMMARY: Despite the adoption of simulation, further study is needed to better qualify its effect on patient safety and outcome.",2013-04,13/11/2018 10:47,14/04/2020 08:35,,159-163,,2,26,,Curr Opin Anaesthesiol,,,,,,,,eng,,,,,,,PMID: 23339975,,,,Humans; Delivery of Health Care; *Patient Simulation; Patient Safety; *Patient Safety; Patient Simulation; Anesthesiology/*education; Health Care Delivery; Anesthesiology – Education; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, SFH4A3YK,journalArticle,2012,"Dow, Alan W.; Salas, Eduardo; Mazmanian, Paul E.",Improving quality in systems of care: solving complicated challenges with simulation-based continuing professional development.,The Journal of continuing education in the health professions,,1554-558X 0894-1912,10.1002/chp.21150,,"The delivery of quality health care depends on the successful interactions of practitioners, teams, and systems of care comprising culture. Designing educational programs to improve these interactions is a major goal of continuing professional development, and one approach for educational planners to effect desired changes is simulation-based education. Because simulation-based education affords an opportunity for educators to train health care professionals in environments that resemble clinical practice, this instructional method allows planners to integrate overarching priorities for improvement in health care practice with the training goals of individuals. Educational planners should consider how to structure scenarios to meet training objectives based on the complicated interactions within the health care system. To optimize the benefit of simulation-based experiences, evidence and insights from industrial and organizational psychology, as well as from human factors studies, provide guidance to the planning process, and interdisciplinary studies of complex health care systems can help produce educational programs that improve the quality of health care delivery.",2012,13/11/2018 10:47,14/04/2020 08:34,,230-235,,4,32,,J Contin Educ Health Prof,,,,,,,,eng,"Copyright (c) 2012 The Alliance for Continuing Education in the Health Professions, the Society for Academic Continuing Medical Education, and the Council on CME, Association for Hospital Medical Education.",,,,,,PMID: 23280525,,,,"Humans; *Computer Simulation; Educational Measurement; Quality Improvement; Interpersonal Relations; Organizational Culture; Organizational Objectives; Problem Solving; Education; *Systems Integration; Competency-Based Education; Education, Medical, Continuing/*methods/organization & administration; Educational Technology; Quality Assurance, Health Care/*standards; Staff Development/*methods; Professional Development; Medical; Interdisciplinary; Simulations – Utilization; Continuing – Trends; Serial Publications; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GUZNFCKZ,journalArticle,2013,"Patterson, Mary D.; Geis, Gary Lee; Falcone, Richard A.; LeMaster, Thomas; Wears, Robert L.",In situ simulation: detection of safety threats and teamwork training in a high risk emergency department.,BMJ quality & safety,,2044-5423 2044-5415,10.1136/bmjqs-2012-000942,,"OBJECTIVE: Implement and demonstrate feasibility of in situ simulations to identify latent safety threats (LSTs) at a higher rate than lab-based training, and reinforce teamwork training in a paediatric emergency department (ED). METHODS: Multidisciplinary healthcare providers responded to critical simulated patients in an urban ED during all shifts. Unannounced in situ simulations were limited to 10 min of simulation and 10 min of debriefing, and were video recorded. A standardised debriefing template was used to assess LSTs. The primary outcome measure was the number and type of LSTs identified during the simulations. Secondary measures included: participants' assessment of impact on patient care and value to participants. Blinded video review using a modified Anaesthetists Non-Technical Skills scale was used to assess team behaviours. RESULTS: 218 healthcare providers responded to 90 in situ simulations conducted over 1 year. A total of 73 LSTs were identified; a rate of one every 1.2 simulations performed. In situ simulations were cancelled at a rate of 28% initially, but the cancellation rate decreased as training matured. Examples of threats identified include malfunctioning equipment and knowledge gaps concerning role responsibilities. 78% of participants rated the simulations as extremely valuable or valuable, while only 5% rated the simulation as having little or no value. Of those responding to a postsimulation survey, 77% reported little or no clinical impact. Video recordings did not indicate changes in non-technical skills during this time. CONCLUSIONS: In situ simulation is a practical method for the detection of LSTs and to reinforce team training behaviours. Embedding in situ simulation as a routine expectation positively affected operations and the safety climate in a high risk clinical setting.",2013-06,13/11/2018 10:47,14/04/2020 08:35,,468-477,,6,22,,BMJ Qual Saf,,,,,,,,eng,,,,,,,PMID: 23258390,,,,"Humans; Staff Development; Outcome Assessment (Health Care); *Patient Simulation; Patient Safety; Academic Medical Centers; Pediatrics; *Models, Educational; Teamwork; Patient Care Team/*organization & administration; Hospitals; Safety culture; Emergency Service, Hospital/*standards; Simulation; Emergency department; Ohio; Medical Staff, Hospital/education; Qualitative research; Risk Management/*methods; Urban Health Services; Equipment Failure; Descriptive Statistics; Human; Patient Simulation – Utilization; Videorecording – Utilization; Scales; Patient Safety – Education; Repeated Measures; Funding Source; Teamwork – Education; Skill Acquisition; Pediatric – Ohio; Professional Knowledge; Emergency Service – Utilization; Feedback – Methods; Multidisciplinary Care Team; Prospective Studies – Ohio; Risk Assessment – Evaluation; Skill Retention; Teamwork – Evaluation; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2LAS2U8F,journalArticle,2013,"Patterson, Mary D.; Geis, Gary L.; LeMaster, Thomas; Wears, Robert L.",Impact of multidisciplinary simulation-based training on patient safety in a paediatric emergency department.,BMJ quality & safety,,2044-5423 2044-5415,10.1136/bmjqs-2012-000951,,"BACKGROUND: Cincinnati Children's Hospital is one of the busiest paediatric emergency departments (ED) in the USA; high volume, high acuity and frequent interruptions contribute to an increased risk for error. OBJECTIVE: To improve patient safety in a paediatric ED by implementing a multidisciplinary, simulation-based curriculum emphasising teamwork and communication. METHODS: Subjects included all healthcare providers in the ED. Multidisciplinary teams participated in simulation-based training focused on teamwork and communication behaviours in critical clinical scenarios. The Safety Attitudes Questionnaire, tests of knowledge and evaluations of critical simulations and actual performance in the ED resuscitation bay were assessed. Methods to sustain improvements included mandatory participation of all new staff in simulation-based training and the introduction of routine in situ simulations. RESULTS: 289 participants attended the initial training. 151 participants attended the re-evaluation at a mean of 10.2 months later. Sustained improvements in knowledge and attitudes were demonstrated. Knowledge tests at baseline, postintervention and re-evaluation had scores of 86%, 96% and 93%, respectively. Friedman's test analysis of SAQ scores at baseline, postintervention and re-evaluation indicated significant attitude changes. The ED with a preintervention baseline of 2-3 patient safety events per year has now sustained more than 1000 days without a patient safety event. This improvement occurred even though the time required in initial simulation training has been condensed from 12 to 4 h. CONCLUSIONS: Simulation training is an effective tool to modify safety attitudes and teamwork behaviours in an ED. Sustaining cultural and behavioural changes requires repeated practice opportunities.",2013-05,13/11/2018 10:47,14/04/2020 08:35,,383-393,,5,22,,BMJ Qual Saf,,,,,,,,eng,,,,,,,PMID: 23258388,,,,"Humans; *Patient Simulation; Resuscitation; *Patient Safety; Interdisciplinary Communication; Teamwork; Models, Organizational; Attitude of Health Personnel; Hospitals; Emergency Service, Hospital/*standards; Patient Care Team/*standards; Ohio; Hospital Departments; Pediatrics/methods/*standards; Quality Assurance, Health Care/methods/standards; Resuscitation/methods/psychology; Analysis of Variance; Human; Outcomes of Education; Emergency Service; Scales; Patient Safety – Education; Repeated Measures; Questionnaires; Funding Source; Communication Skills Training; Pediatric – Ohio; Multidisciplinary Care Team; Prospective Studies – Ohio; Skill Retention; Course Content; Friedman Test; Post Hoc Analysis; Simulations – Utilization; Wilcoxon Rank Sum Test; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5NW6CDCR,journalArticle,2013,"Ross, Alastair J.; Anderson, Janet E.; Kodate, Naonori; Thomas, Libby; Thompson, Kellie; Thomas, Beth; Key, Suzie; Jensen, Heidi; Schiff, Rebekah; Jaye, Peter",Simulation training for improving the quality of care for older people: an independent evaluation of an innovative programme for inter-professional education.,BMJ quality & safety,,2044-5423 2044-5415,10.1136/bmjqs-2012-000954,,"INTRODUCTION: This paper describes the evaluation of a 2-day simulation training programme for staff designed to improve teamwork and inpatient care and compassion in an older persons' unit. OBJECTIVE: The programme was designed to improve inpatient care for older people by using mixed modality simulation exercises to enhance teamwork and empathetic and compassionate care. METHODS: Healthcare professionals took part in: (a) a 1-day human patient simulation course with six scenarios and (b) a 1-day ward-based simulation course involving five 1-h exercises with integrated debriefing. A mixed methods evaluation included observations of the programme, precourse and postcourse confidence rating scales and follow-up interviews with staff at 7-9 weeks post-training. RESULTS: Observations showed enjoyment of the course but some anxiety and apprehension about the simulation environment. Staff self-confidence improved after human patient simulation (t=9; df=56; p<0.001) and ward-based exercises (t=9.3; df=76; p<0.001). Thematic analysis of interview data showed learning in teamwork and patient care. Participants thought that simulation had been beneficial for team practices such as calling for help and verbalising concerns and for improved interaction with patients. Areas to address in future include widening participation across multi-disciplinary teams, enhancing post-training support and exploring further which aspects of the programme enhance compassion and care of older persons. CONCLUSIONS: The study demonstrated that simulation is an effective method for encouraging dignified care and compassion for older persons by teaching team skills and empathetic and sensitive communication with patients and relatives.",2013-06,13/11/2018 10:47,14/04/2020 08:35,,495-505,,6,22,,BMJ Qual Saf,,,,,,,,eng,,,,,,,PMID: 23220568,,,,"Humans; *Quality Assurance, Health Care; Program Evaluation; Surveys and Questionnaires; *Patient Simulation; Patient Care Team/organization & administration; Aged; Patient-Centered Care; *Computer Simulation; Program Development; Communication; Models, Theoretical; Quality Improvement; *Interprofessional Relations; Health Personnel/*education; Inpatients; Manikins; Simulation; Empathy; Education; Organizational Innovation; Comprehensive Health Care/organization & administration; Health Services for the Aged/*standards; Hospital Units/manpower; Outcome and Process Assessment (Health Care)/methods; Patient-centred care; Professional-Patient Relations; Team training; Role Playing; Human; Outcomes of Education; Patient Simulation – Utilization; Pretest-Posttest Design; Vignettes; Multimethod Studies; Thematic Analysis; Funding Source; Interviews; Communication Skills Training; Observational Methods; Interdisciplinary; Registered Nurses; Teamwork – Education; Nursing Assistants; Skill Retention; Aptitude Tests; Confidence; Geriatrics – Education; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TFC9WEAK,journalArticle,2012,"Menzies, Nicolas A.; Cohen, Ted; Lin, Hsien-Ho; Murray, Megan; Salomon, Joshua A.",Population health impact and cost-effectiveness of tuberculosis diagnosis with Xpert MTB/RIF: a dynamic simulation and economic evaluation.,PLoS medicine,,1549-1676 1549-1277,10.1371/journal.pmed.1001347,,"BACKGROUND: The Xpert MTB/RIF test enables rapid detection of tuberculosis (TB) and rifampicin resistance. The World Health Organization recommends Xpert for initial diagnosis in individuals suspected of having multidrug-resistant TB (MDR-TB) or HIV-associated TB, and many countries are moving quickly toward adopting Xpert. As roll-out proceeds, it is essential to understand the potential health impact and cost-effectiveness of diagnostic strategies based on Xpert. METHODS AND FINDINGS: We evaluated potential health and economic consequences of implementing Xpert in five southern African countries--Botswana, Lesotho, Namibia, South Africa, and Swaziland--where drug resistance and TB-HIV coinfection are prevalent. Using a calibrated, dynamic mathematical model, we compared the status quo diagnostic algorithm, emphasizing sputum smear, against an algorithm incorporating Xpert for initial diagnosis. Results were projected over 10- and 20-y time periods starting from 2012. Compared to status quo, implementation of Xpert would avert 132,000 (95% CI: 55,000-284,000) TB cases and 182,000 (97,000-302,000) TB deaths in southern Africa over the 10 y following introduction, and would reduce prevalence by 28% (14%-40%) by 2022, with more modest reductions in incidence. Health system costs are projected to increase substantially with Xpert, by US$460 million (294-699 million) over 10 y. Antiretroviral therapy for HIV represents a substantial fraction of these additional costs, because of improved survival in TB/HIV-infected populations through better TB case-finding and treatment. Costs for treating MDR-TB are also expected to rise significantly with Xpert scale-up. Relative to status quo, Xpert has an estimated cost-effectiveness of US$959 (633-1,485) per disability-adjusted life-year averted over 10 y. Across countries, cost-effectiveness ratios ranged from US$792 (482-1,785) in Swaziland to US$1,257 (767-2,276) in Botswana. Assessing outcomes over a 10-y period focuses on the near-term consequences of Xpert adoption, but the cost-effectiveness results are conservative, with cost-effectiveness ratios assessed over a 20-y time horizon approximately 20% lower than the 10-y values. CONCLUSIONS: Introduction of Xpert could substantially change TB morbidity and mortality through improved case-finding and treatment, with more limited impact on long-term transmission dynamics. Despite extant uncertainty about TB natural history and intervention impact in southern Africa, adoption of Xpert evidently offers reasonable value for its cost, based on conventional benchmarks for cost-effectiveness. However, the additional financial burden would be substantial, including significant increases in costs for treating HIV and MDR-TB. Given the fundamental influence of HIV on TB dynamics and intervention costs, care should be taken when interpreting the results of this analysis outside of settings with high HIV prevalence.",2012,13/11/2018 10:47,14/04/2020 08:34,,e1001347,,11,9,,PLoS Med,,,,,,,,eng,,,,,,,PMID: 23185139 PMCID: PMC3502465,,,,"Humans; Cost-Benefit Analysis; Models, Theoretical; Africa; Prevalence; Mortality; *Drug Resistance, Bacterial; Africa, Southern; Antibiotics, Antitubercular/*therapeutic use; Clinical Laboratory Techniques/economics/*methods; Mycobacterium tuberculosis/drug effects/genetics/*isolation & purification; Real-Time Polymerase Chain Reaction/economics/*methods; Rifampin/*pharmacology; Sputum/microbiology; Tuberculosis, Pulmonary/*diagnosis/economics; Drug Resistance; 1; Models; Theoretical; Cost Benefit Analysis; Diagnosis; Antibiotics; Antitubercular – Therapeutic Use; Laboratory – Economics; Laboratory – Methods; Microbial; Mycobacterium Tuberculosis; Polymerase Chain Reaction – Economics; Polymerase Chain Reaction – Methods; Pulmonary – Diagnosis; Pulmonary – Economics; Rifampin – Pharmacodynamics; Southern; Sputum – Microbiology; Tuberculosis; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, U7Z4QWJ9,journalArticle,2012,"Fay-Hillier, Theresa M.; Regan, Roseann V.; Gallagher Gordon, Mary",Communication and patient safety in simulation for mental health nursing education.,Issues in mental health nursing,,1096-4673 0161-2840,10.3109/01612840.2012.709585,,"The Joint Commission on Accreditation of Healthcare Organizations (JCAHO) found that 65% of medical sentinel events or medical errors are associated with communication breakdowns. In addition to the JCAHO, The Institute of Medicine, in their Core Competencies for health care professional education, recommend improvement in professional communication, collaboration, and a patient-centered approach to provide safety. Consistency of opportunities for students to practice their communication and collaboration skills is limited based on the variety of clinical experiences that are available. Simulation would provide consistency in students' experiences. Students can practice giving a structured report, providing and receiving peer feedback, and obtaining patient feedback in a safe setting through a simulation experience. A structured hand-off shift report using a technique such as SBAR communication has been found to improve patient safety in health care environments. This paper examines the implementation of a simulation experience for students taking a Mental Health course in a Bachelor of Science in Nursing (BSN) Program to support their practice of patient and professional communication, as well as, collaboration skills with a patient-centered approach using a standardized patient simulation.",2012-11,13/11/2018 10:47,14/04/2020 08:34,,718-726,,11,33,,Issues Ment Health Nurs,,,,,,,,eng,,,,,,,PMID: 23146005,,,,"Humans; *Patient Simulation; Patient Safety; Curriculum; Communication; Psychiatric Nursing/*education; Educational Measurement; *Patient Safety; Teamwork; *Communication; *Education, Nursing, Baccalaureate; Collaboration; Patient Simulation; Peer Group; Professional-Patient Relations; *Nurse-Patient Relations; Interview, Psychological; Mental Disorders/nursing/psychology; Nursing, Team; Therapeutic Community; Program Implementation; Patient Centered Care; Psychiatric Nursing – Education; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 483R4JCJ,journalArticle,2012,"Eddy, David M.; Shah, Roshan",A simulation shows limited savings from meeting quality targets under the Medicare Shared Savings Program.,Health affairs (Project Hope),,1544-5208 0278-2715,10.1377/hlthaff.2012.0385,,"The Medicare Shared Savings Program, created under the Affordable Care Act, will reward participating accountable care organizations that succeed in lowering health care costs while improving performance. Depending on how the organizations perform on several quality measures, they will ""share savings"" in Medicare Part A and B payments-that is, they will receive bonus payments for lowering costs. We used a simulation model to analyze the effects of the Shared Savings Program quality measures and performance targets on Medicare costs in a simulated population of patients ages 65-75 with type 2 diabetes. We found that a ten-percentage-point improvement in performance on diabetes quality measures would reduce Medicare costs only by up to about 1 percent. After the costs of performance improvement, such as additional tests or visits, are accounted for, the savings would decrease or become cost increases. To achieve greater savings, accountable care organizations will have to lower costs by other means, such as through improved use of information technology and care coordination.",2012-11,13/11/2018 10:47,14/04/2020 08:34,,2554-2562,,11,31,,Health Aff (Millwood),,,,,,,,eng,,,,,,,PMID: 23035036,,,,Humans; United States; Health Care Costs; Male; Patient Safety; Aged; Computer Simulation; Quality Improvement; Health Expenditures; Patient Protection and Affordable Care Act; Medicare; *Cost Sharing; Accountable Care Organizations/*economics; Cost Savings/*economics; Medicare/*economics; Patient Protection and Affordable Care Act/*economics; Cost Savings; Benchmarking; 1; ****; Human; Vignettes; Funding Source; Diabetes Mellitus; Computer Simulation – Utilization; Case Management; Type 2 – Therapy; Preventive Health Care; Goal Attainment; Forecasting (Research); Glycemic Control; Performance Measurement Systems; Agent Based; 310,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WYYW7XEZ,journalArticle,2009,"Waterson, Patrick",A critical review of the systems approach within patient safety research.,Ergonomics,,1366-5847 0014-0139,10.1080/00140130903042782,,"The application of concepts, theories and methods from systems ergonomics within patient safety has proved to be an expanding area of research and application in the last decade. This paper aims to take a step back and examine what types of research have been conducted so far and use the results to suggest new ways forward. An analysis of a selection of the patient safety literature suggests that research has so far focused on human error, frameworks for safety and risk and incident reporting. The majority of studies have addressed system concerns at an individual level of analysis with only a few analysing systems across multiple system boundaries. Based on the findings, it is argued that future research needs to move away from a concentration on errors and towards an examination of the connections between systems levels. Examples of how this could be achieved are described in the paper. The outcomes from the review of the systems approach within patient safety provide practitioners and researchers within health care (e.g. the UK National Health Service) with a picture of what types of research are currently being investigated, gaps in understanding and possible future ways forward.",2009-10,13/11/2018 10:47,14/04/2020 08:35,,1185-1195,,10,52,,Ergonomics,,,,,,,,eng,,,,,,,PMID: 19787499,,,,Humans; Medical Errors/prevention & control; Patient Safety; *Systems Analysis; United Kingdom; *Safety Management; Hospitals; Organizational Culture; Systems Theory; Ergonomics; Technology; *Health Services Research; *Ergonomics; 1; Descriptive Statistics; Human; Treatment Errors – Prevention and Control; Evidence-Based; Professional Practice; PubMed; Multidisciplinary Care Team; Organizational Structure; Human Error; Mandatory Reporting; Treatment Errors – Etiology; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7XLGMULD,journalArticle,2013,"Nshimyumukiza, Leon; Durand, Audrey; Gagnon, Mathieu; Douville, Xavier; Morin, Suzanne; Lindsay, Carmen; Duplantie, Julie; Gagne, Christian; Jean, Sonia; Giguere, Yves; Dodin, Sylvie; Rousseau, Francois; Reinharz, Daniel",An economic evaluation: Simulation of the cost-effectiveness and cost-utility of universal prevention strategies against osteoporosis-related fractures.,Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research,,1523-4681 0884-0431,10.1002/jbmr.1758,,"A patient-level Markov decision model was used to simulate a virtual cohort of 500,000 women 40 years old and over, in relation to osteoporosis-related hip, clinical vertebral, and wrist bone fractures events. Sixteen different screening options of three main scenario groups were compared: (1) the status quo (no specific national prevention program); (2) a universal primary prevention program; and (3) a universal screening and treatment program based on the 10-year absolute risk of fracture. The outcomes measured were total directs costs from the perspective of the public health care system, number of fractures, and quality-adjusted life-years (QALYs). Results show that an option consisting of a program promoting physical activity and treatment if a fracture occurs is the most cost-effective (CE) (cost/fracture averted) alternative and also the only cost saving one, especially for women 40 to 64 years old. In women who are 65 years and over, bone mineral density (BMD)-based screening and treatment based on the 10-year absolute fracture risk calculated using a Canadian Association of Radiologists and Osteoporosis Canada (CAROC) tool is the best next alternative. In terms of cost-utility (CU), results were similar. For women less than 65 years old, a program promoting physical activity emerged as cost-saving but BMD-based screening with pharmacological treatment also emerged as an interesting alternative. In conclusion, a program promoting physical activity is the most CE and CU option for women 40 to 64 years old. BMD screening and pharmacological treatment might be considered a reasonable alternative for women 65 years old and over because at a healthcare capacity of $50,000 Canadian dollars ($CAD) for each additional fracture averted or for one QALY gained its probabilities of cost-effectiveness compared to the program promoting physical activity are 63% and 75%, respectively, which could be considered socially acceptable. Consideration of the indirect costs could change these findings.",2013-02,13/11/2018 10:47,14/04/2020 08:35,,383-394,,2,28,,J Bone Miner Res,,,,,,,,eng,Copyright (c) 2013 American Society for Bone and Mineral Research.,,,,,,PMID: 22991210 PMCID: PMC3580046,,,,"Humans; Canada; Cost-Benefit Analysis; Adult; Female; Middle Aged; Aged; Decision Support Techniques; *Computer Simulation; Aged, 80 and over; Osteoporosis/*complications/economics; Osteoporotic Fractures/complications/*economics/*prevention & control/therapy; 1; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, X9UFF2BM,journalArticle,2012,"Yousefi-Nooraie, Reza; Dobbins, Maureen; Brouwers, Melissa; Wakefield, Patricia",Information seeking for making evidence-informed decisions: a social network analysis on the staff of a public health department in Canada.,BMC health services research,,1472-6963 1472-6963,10.1186/1472-6963-12-118,,"BACKGROUND: Social network analysis is an approach to study the interactions and exchange of resources among people. It can help understanding the underlying structural and behavioral complexities that influence the process of capacity building towards evidence-informed decision making. A social network analysis was conducted to understand if and how the staff of a public health department in Ontario turn to peers to get help incorporating research evidence into practice. METHODS: The staff were invited to respond to an online questionnaire inquiring about information seeking behavior, identification of colleague expertise, and friendship status. Three networks were developed based on the 170 participants. Overall shape, key indices, the most central people and brokers, and their characteristics were identified. RESULTS: The network analysis showed a low density and localized information-seeking network. Inter-personal connections were mainly clustered by organizational divisions; and people tended to limit information-seeking connections to a handful of peers in their division. However, recognition of expertise and friendship networks showed more cross-divisional connections. Members of the office of the Medical Officer of Health were located at the heart of the department, bridging across divisions. A small group of professional consultants and middle managers were the most-central staff in the network, also connecting their divisions to the center of the information-seeking network. In each division, there were some locally central staff, mainly practitioners, who connected their neighboring peers; but they were not necessarily connected to other experts or managers. CONCLUSIONS: The methods of social network analysis were useful in providing a systems approach to understand how knowledge might flow in an organization. The findings of this study can be used to identify early adopters of knowledge translation interventions, forming Communities of Practice, and potential internal knowledge brokers.",16/05/2012,13/11/2018 10:47,14/04/2020 08:35,,118,,,12,,BMC Health Serv Res,,,,,,,,eng,,,,,,,PMID: 22591757 PMCID: PMC3496590,,,,Humans; Ontario; Surveys and Questionnaires; *Public Health; Decision Making; Public Health; Cross-Sectional Studies; *Social Support; *Decision Making; *Evidence-Based Medicine; *Information Seeking Behavior; 1; Human; Questionnaires; Support; Evidence-Based; Cross Sectional Studies; Psychosocial; Medical Practice; Information Seeking Behavior; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ITIU67G7,journalArticle,2012,"Hunter, David; Perkins, Neil",Partnership working in public health: the implications for governance of a systems approach.,Journal of health services research & policy,,1758-1060 1355-8196,10.1258/jhsrp.2012.011127,,"OBJECTIVES: Most of the research on partnerships has centred on health and social care, and while many of the findings remain relevant, public health partnerships concerned with 'wicked issues' give rise to a different and more complex set of issues which merit exploration. The study aimed to identify those factors promoting effective partnership working for health improvement; to assess the extent to which partnership governance and incentive arrangements were commensurate with the complexities of the problem; and to explore how far local partnerships contributed to better outcomes for individuals and populations. METHODS: A three-year study of public health partnerships (2007-10) in nine localities across England involving semi-structured interviews at strategic and operational levels. RESULTS: Successful partnerships shared a number of characteristics: they were clear about goals and purpose; they were aware of partners' roles and responsibilities; and they had a clear strategic overview of performance through robust monitoring and evaluation. In many cases, partnerships were facades with a 'silo mentality' prevailing - there was an unwillingness to share information or resources, or to accord partnership working sufficient priority or support. Despite enthusiasm for partnerships and an insistence that they were essential, it was impossible to establish evidence of their impact on health outcomes. While the focus on partnerships tends to be on structures, relational factors, including high levels of trust and goodwill, were important ingredients of a well-functioning partnership. Less formal and more organic, operational partnerships were more effective than more formal, strategic level ones which were driven by targets. Finally, partnerships were, in part, shaped by the national policy context, with constant policy and organizational churn making it difficult to sustain long-term relationships. CONCLUSIONS: Future partnerships might be undertaken differently, adopting a complex adaptive systems perspective. This advocates an approach to partnership working that is less focused on rigid structures and much more on relational factors like trust and goodwill.",2012-04,13/11/2018 10:47,14/04/2020 08:34,,45-52,,,17 Suppl 2,,J Health Serv Res Policy,,,,,,,,eng,,,,,,,PMID: 22572716,,,,Humans; Health Policy; Local Government; Health Services Research; Qualitative Research; Time Factors; Quality Improvement; *Public Health Practice; *Cooperative Behavior; England; State Medicine/*organization & administration; Trust; Public Health Administration; Interinstitutional Relations; Organizational Change; Goals and Objectives; Outcomes (Health Care); Organizational Structure; Performance Measurement Systems; Collaboration – Methods; Governing Board; Politics; Role; Strategic Planning; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6HJQQBY4,journalArticle,2012,"Demirtas, Hakan; Hedeker, Donald; Mermelstein, Robin J.",Simulation of massive public health data by power polynomials.,Statistics in medicine,,1097-0258 0277-6715,10.1002/sim.5362,,"Situations in which multiple outcomes and predictors of different distributional types are collected are becoming increasingly common in public health practice, and joint modeling of mixed types has been gaining popularity in recent years. Evaluation of various statistical techniques that have been developed for mixed data in simulated environments necessarily requires joint generation of multiple variables. Most massive public health data sets include different types of variables. For instance, in clustered or longitudinal designs, often multiple variables are measured or observed for each individual or at each occasion. This work is motivated by a need to jointly generate binary and possibly non-normal continuous variables. We illustrate the use of power polynomials to simulate multivariate mixed data on the basis of a real adolescent smoking study. We believe that our proposed technique for simulating such intensive data has the potential to be a handy methodological addition to public health researchers' toolkit.",30/11/2012,13/11/2018 10:47,14/04/2020 08:34,,3337-3346,,27,31,,Stat Med,,,,,,,,eng,"Copyright (c) 2012 John Wiley & Sons, Ltd.",,,,,,PMID: 22532052 PMCID: PMC3650647,,,,"Humans; Female; Male; *Models, Statistical; Adolescent; Public Health/*methods; Computer Simulation; *Data Interpretation, Statistical; *Multivariate Analysis; Affect; Smoking/psychology; Models; Statistical; Data Analysis; Adolescence; Multivariate Analysis; Public Health – Methods; Smoking – Psychosocial Factors; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GNTGIUF3,journalArticle,2012,"Demarteau, Nadia; Breuer, Thomas; Standaert, Baudouin",Selecting a mix of prevention strategies against cervical cancer for maximum efficiency with an optimization program.,PharmacoEconomics,,1179-2027 1170-7690,10.2165/11591560-000000000-00000,,"BACKGROUND: Screening and vaccination against human papillomavirus (HPV) can protect against cervical cancer. Neither alone can provide 100% protection. Consequently it raises the important question about the most efficient combination of screening at specified time intervals and vaccination to prevent cervical cancer. OBJECTIVE: Our objective was to identify the mix of cervical cancer prevention strategies (screening and/or vaccination against HPV) that achieves maximum reduction in cancer cases within a fixed budget. METHODS: We assessed the optimal mix of strategies for the prevention of cervical cancer using an optimization program. The evaluation used two models. One was a Markov cohort model used as the evaluation model to estimate the costs and outcomes of 52 different prevention strategies. The other was an optimization model in which the results of each prevention strategy of the previous model were entered as input data. The latter model determined the combination of the different prevention options to minimize cervical cancer under budget, screening coverage and vaccination coverage constraints. We applied the model in two countries with different healthcare organizations, epidemiology, screening practices, resource settings and treatment costs: the UK and Brazil. 100,000 women aged 12 years and above across the whole population over a 1-year period at steady state were included. The intervention was papanicolaou (Pap) smear screening programmes and/or vaccination against HPV with the bivalent HPV 16/18 vaccine (Cervarix(R) [Cervarix is a registered trademark of the GlaxoSmithKline group of companies]). The main outcome measures were optimal distribution of the population between different interventions (screening, vaccination, screening plus vaccination and no screening or vaccination) with the resulting number of cervical cancer and associated costs. RESULTS: In the base-case analysis (= same budget as today), the optimal prevention strategy would be, after introducing vaccination with a coverage rate of 80% in girls aged 12 years and retaining screening coverage at pre-vaccination levels (65% in the UK, 50% in Brazil), to increase the screening interval to 6 years (from 3) in the UK and to 5 years (from 3) in Brazil. This would result in a reduction of cervical cancer by 41% in the UK and by 54% in Brazil from pre-vaccination levels with no budget increase. Sensitivity analysis shows that vaccination alone at 80% coverage with no screening would achieve a cervical cancer reduction rate of 20% in the UK and 43% in Brazil compared with the pre-vaccination situation with a budget reduction of 30% and 14%, respectively. In both countries, the sharp reduction in cervical cancer is seen when the vaccine coverage rate exceeds the maximum screening coverage rate, or when screening coverage rate exceeds the maximum vaccine coverage rate, while maintaining the budget. As with any model, there are limitations to the value of predictions depending upon the assumptions made in each model. CONCLUSIONS: Spending the same budget that was used for screening and treatment of cervical cancer in the pre-vaccination era, results of the optimization program show that it would be possible to substantially reduce the number of cases by implementing an optimal combination of HPV vaccination (80% coverage) and screening at pre-vaccination coverage (65% UK, 50% Brazil) while extending the screening interval to every 6 years in the UK and 5 years in Brazil.",2012-04,13/11/2018 10:47,14/04/2020 08:34,,337-353,,4,30,,Pharmacoeconomics,,,,,,,,eng,,,,,,,PMID: 22409292,,,,"Humans; United States; Adult; Female; Middle Aged; Young Adult; Aged; Markov Chains; Child; Adolescent; United States/epidemiology; Models, Theoretical; Time Factors; Probability; Mass Screening/economics/*methods; Brazil; Brazil/epidemiology; Papillomavirus Infections/complications/diagnosis/*prevention & control; Papillomavirus Vaccines/*administration & dosage/economics; Uterine Cervical Neoplasms/economics/*prevention & control/virology; Human; Models; Theoretical; Middle Age; Adolescence; Cervix Neoplasms; Cervix Neoplasms – Economics; Cervix Neoplasms – Prevention and Control; Health Screening – Economics; Health Screening – Methods; Papillomavirus Infections – Complications; Papillomavirus Infections – Diagnosis; Papillomavirus Infections – Prevention and Control; Papillomavirus Vaccine – Administration and Dosage; Papillomavirus Vaccine – Economics; 00; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ZMP2M6D9,journalArticle,2012,"Montgomery, Kymberlee; Morse, Catherine; Smith-Glasgow, Mary Ellen; Posmontier, Bobbie; Follen, Michele",Promoting quality and safety in women's health through the use of transdisciplinary clinical simulation educational modules: methodology and a pilot trial.,Gender medicine,,1878-7398 1550-8579,10.1016/j.genm.2011.11.001,,This manuscript presents the methodology used to assess the impact of a clinical simulation module used for training providers specializing in women's health. The methodology presented here will be used for a quantitative study in the future.,2012-02,13/11/2018 10:47,14/04/2020 08:35,,S48-54,,1 Suppl,9,,Gend Med,,,,,,,,eng,"Copyright (c) 2012 Elsevier HS Journals, Inc. All rights reserved.",,,,,,PMID: 22340640,,,,"Humans; Quality of Health Care; Patient Safety; Program Development; Computer Simulation; Pilot Projects; *Models, Educational; Research Design; Interdisciplinary Communication; Manikins; Collaboration; Pennsylvania; Education; Women's Health/*education; Human; Outcomes of Education; Teaching Methods; Pilot Studies; Computer Simulation – Utilization; Interdisciplinary; Learning Environment; Mentorship; Women's Health; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 844CEHQP,journalArticle,2012,"Edwards, Rachel; Charani, Esmita; Sevdalis, Nick; Alexandrou, Banos; Sibley, Eleanor; Mullett, David; Loveday, Heather P.; Drumright, Lydia N.; Holmes, Alison",Optimisation of infection prevention and control in acute health care by use of behaviour change: a systematic review.,The Lancet. Infectious diseases,,1474-4457 1473-3099,10.1016/S1473-3099(11)70283-3,,"Changes in the behaviour of health-care workers (HCWs) are required to improve adherence to infection prevention and control (IPC) guidelines. Despite heavy investment in strategies to change behaviour, effectiveness has not been adequately assessed. We did a systematic review to assess the effectiveness and sustainability of interventions to change IPC behaviour and assessed exploratory literature for barriers to and facilitators of behaviour change. 21 studies published from 1999 to 2011 met our inclusion criteria: seven intervention studies and 14 exploratory studies. Of the intervention studies none explicitly incorporated psychological theory and only two contained elements of social marketing in the design, although five addressed sustainability. All elicited behaviour change, reduction in infection risk, or both. The exploratory studies identified social and cultural factors that affect the IPC behaviour of HCWs. To improve the standard of research and broaden the evidence base, we recommend that quality criteria are added to existing systematic review guidelines to enable the inclusion of qualitative research and to ensure robust design, implementation, and reporting of interventions.",2012-04,13/11/2018 10:47,14/04/2020 08:34,,318-329,,4,12,,Lancet Infect Dis,,,,,,,,eng,Copyright (c) 2012 Elsevier Ltd. All rights reserved.,,,,,,PMID: 22342325,,,,Humans; Health Personnel; Behavior Therapy/*methods/standards; Infection Control/*methods/standards; Human; Systematic Review; Behavior Therapy – Methods; Behavior Therapy – Standards; Infection Control – Methods; Infection Control – Standards; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DEJEWCH7,journalArticle,2012,"By, Asa; Sobocki, Patrik; Forsgren, Arne; Silfverdal, Sven-Arne",Comparing health outcomes and costs of general vaccination with pneumococcal conjugate vaccines in Sweden: a Markov model.,Clinical therapeutics,,1879-114X 0149-2918,10.1016/j.clinthera.2011.12.007,,"BACKGROUND: Two new pneumococcal conjugate vaccines were licensed to immunize infants and young children against pneumococcal disease. OBJECTIVES: The objective of this study was to estimate the expected health benefits, costs, and incremental cost-effectiveness of routine vaccination with the 10-valent pneumococcal nontypeable hemophilus influenza protein-D conjugate vaccine (PHiD-CV) compared with the 13-valent pneumococcal conjugate vaccine (PCV13) in Sweden. METHODS: A Markov cohort model was used to estimate the effect of vaccination at vaccine steady state, taking a societal perspective and using a 2+1 vaccination schedule. Price parity was assumed between the vaccines. Outcomes were measured by reduction in disease burden, costs, quality-adjusted life-years (QALYs) and incremental cost-effectiveness ratio. RESULTS: The results predicted that PCV13 would prevent 3 additional cases of invasive pneumococcal disease and 34 additional cases of pneumonia, whereas PHiD-CV would avoid 3 additional cases of mastoiditis, 1010 tube insertions, and 10,420 cases of ambulatory acute otitis media compared with PCV13. By combining morbidity and mortality benefits of all clinical outcomes, PHiD-CV would generate 45.3 additional QALYs compared with PCV13 and generate savings of an estimated 62 million Swedish kronors. CONCLUSION: The present study predicted lower costs and better health outcome (QALYs) gained by introducing PHiD-CV compared with PCV13 in routine vaccination. Our results indicated that PHiD-CV is cost-effective compared with PCV13 in Sweden.",2012-01,13/11/2018 10:47,14/04/2020 08:34,,177-189,,1,34,,Clin Ther,,,,,,,,eng,"Copyright (c) 2012 Elsevier HS Journals, Inc. All rights reserved.",,,,,,PMID: 22284997,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Treatment Outcome; *Models, Economic; *Markov Chains; Infant; Sweden; Sensitivity and Specificity; Sweden/epidemiology; *Drug Costs; Cost Savings; Immunization Schedule; Outcome and Process Assessment (Health Care)/*economics; Pneumococcal Infections/*economics/epidemiology/microbiology/*prevention & control; Pneumococcal Vaccines/*administration & dosage/adverse effects/*economics; Human; Cost Benefit Analysis; Funding Source; Treatment Outcomes; Immunization – Utilization; Pneumococcal Infections – Prevention and Control; 00; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KHEXZ5ZJ,journalArticle,2012,"Thraen, Iona; Bair, Byron; Mullin, Shantel; Weir, Charlene R.","Characterizing ""information transfer"" by using a Joint Cognitive Systems model to improve continuity of care in the aged.",International journal of medical informatics,,1872-8243 1386-5056,10.1016/j.ijmedinf.2011.11.006,,"PURPOSE: This study explores multidisciplinary and cross-sector health professional experiences with the information needs for safe patient transfers across the care continuum using a Joint Cognitive Systems (JCS) model. Qualitative experiences of three JCS components and their attributes and are presented. METHODS: A qualitative content analysis using Joint Cognitive Systems constructs were extracted from sixteen multidisciplinary and cross-sector health professional interviews. Participants were asked to describe their information needs and experiences with the patient transfer process. RESULTS: Information transfer associated with three JCS constructs (alignment of goals, enhanced control, and co-agency dynamics) was examined. The breakdown in the information transfer process might be due to the relative strengths of each sector's core expertise. Alignment must cross settings and disciplines and consist of the: (1) transfer of goal relevant and integrated information; (2) accommodation to the control attributes of increased clinical complexity, lack of systematic work processes and feedback or feed forward information; and (3) improvement in the co-agency dynamics of interdependency, trust, inter-related actions and expertise. CONCLUSIONS: Economic pressures and care complexities of the aged require improved effectiveness and efficiencies in the information transfer process. This study aims to understand the information transfer needs from hospitals to skilled nursing care laying a foundation towards a medical informatics solution. An informatics solution must accommodate the differing contextual environments and subsequent information needs and paradigms of the Joint Cognitive System of care across the continuum.",2012-07,13/11/2018 10:47,14/04/2020 08:35,,435-441,,7,81,,Int J Med Inform,,,,,,,,eng,Copyright (c) 2011 Elsevier Ireland Ltd. All rights reserved.,,,,,,PMID: 22226926,,,,Humans; Aged; *Continuity of Patient Care; *Computer Simulation; *Cognition; 1; Joint Cognitive System; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, M67RV6WS,journalArticle,2012,"Luke, Douglas A.; Stamatakis, Katherine A.","Systems science methods in public health: dynamics, networks, and agents.",Annual review of public health,,1545-2093 0163-7525,10.1146/annurev-publhealth-031210-101222,,"Complex systems abound in public health. Complex systems are made up of heterogeneous elements that interact with one another, have emergent properties that are not explained by understanding the individual elements of the system, persist over time, and adapt to changing circumstances. Public health is starting to use results from systems science studies to shape practice and policy, for example in preparing for global pandemics. However, systems science study designs and analytic methods remain underutilized and are not widely featured in public health curricula or training. In this review we present an argument for the utility of systems science methods in public health, introduce three important systems science methods (system dynamics, network analysis, and agent-based modeling), and provide three case studies in which these methods have been used to answer important public health science questions in the areas of infectious disease, tobacco control, and obesity.",2012-04,13/11/2018 10:47,14/04/2020 08:34,,357-376,,,33,,Annu Rev Public Health,,,,,,,,eng,,,,,,,PMID: 22224885 PMCID: PMC3644212,,,,"*Health Policy; Humans; Health Policy; Health Promotion; United States; *Public Health; Public Health; *Public Health Administration; *Delivery of Health Care, Integrated; Public Health Administration; 1; Health Care Delivery; Integrated; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GRLMJGJU,journalArticle,2011,"Dickerson, Justin B.; Smith, Matthew Lee; Dowdy, Diane M.; McKinley, Ashley; Ahn, Sangnam; Ory, Marcia G.",Advanced practice nurses' perspectives on the use of health optimization strategies for managing chronic disease among older adults in different care settings: pushing the boundaries of self-management programs.,"Geriatric nursing (New York, N.Y.)",,1528-3984 0197-4572,10.1016/j.gerinurse.2011.09.001,,"This study examines the intention of advanced practice nurses (APNs) to utilize health optimization programs (HOPs) for addressing clients' chronic disease in various work settings (i.e., nursing homes or other care settings). A paper-based survey was administered to 270 APNs at a continuing education conference to determine their intentions to refer patients to HOPs for chronic disease management. APNs working in nursing homes were 0.23 times as likely to utilize HOPs for management of their patients' chronic disease compared with their counterparts working in other care settings (odds ratio = 0.23, confidence interval = 0.06-0.80, P = .021). APNs who had previously used a HOP for management of their patients' chronic disease were 5.2 times as likely to do so again relative to those who had not previously used a HOP for management of their patients' chronic disease (odds ratio = 5.17, confidence interval = 1.78-14.99, P = .002). Educational and organizational interventions are recommended to disseminate further HOPs for chronic disease in nursing home settings as part of an overall health optimization strategy.",2011-12,13/11/2018 10:47,14/04/2020 08:34,,429-438,,6,32,,Geriatr Nurs,,,,,,,,eng,"Copyright (c) 2011 Mosby, Inc. All rights reserved.",,,,,,PMID: 22055641,,,,Humans; Surveys and Questionnaires; Adult; Female; Male; Middle Aged; Aged; *Geriatric Nursing; Bayes Theorem; Ambulatory Care Facilities; Texas; Hospitals; *Self Care; *Advanced Practice Nursing; *Nursing Homes; Chi-Square Distribution; Chronic Disease/*nursing; Confidence Intervals; Odds Ratio; Descriptive Statistics; Human; Data Analysis Software; Middle Age; Questionnaires; Surveys; Nursing Homes; Advanced Practice Nurses; Chi Square Test; Dependent Variable; Disease Management – In Old Age; Gerontologic Nursing; Independent Variable; Logistic Regression; Patient Education – In Old Age; Self Care – Education – In Old Age; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8M8KJQJH,journalArticle,2011,"Thomson, Jessica L.; Tussing-Humphreys, Lisa M.; Onufrak, Stephen J.; Zoellner, Jamie M.; Connell, Carol L.; Bogle, Margaret L.; Yadrick, Kathy",A simulation study of the potential effects of healthy food and beverage substitutions on diet quality and total energy intake in Lower Mississippi Delta adults.,The Journal of nutrition,,1541-6100 0022-3166,10.3945/jn.111.144659,,"The majority of adult diets in the United States, particularly the South, are of poor quality, putting these individuals at increased risk for chronic diseases. In this study, simulation modeling was used to determine the effects of substituting familiar, more healthful foods and beverages for less healthy ones on diet quality and total energy intake in Lower Mississippi Delta (LMD) adults. Dietary data collected in 2000 for 1689 LMD adults who participated in the Foods of Our Delta Study were analyzed. The Healthy Eating Index-2005 (HEI-2005) was used to measure diet quality. The effects of substituting targeted foods and beverages with more healthful items on diet quality were simulated by replacing the targeted items' nutrient profile with their replacements' profile. For the single food and beverage groups, 100% replacement of grain desserts with juice-packed fruit cocktail and sugar-sweetened beverages with water resulted in the largest improvements in diet quality (4.0 and 3.8 points, respectively) and greatest decreases in total energy intake (98 and 215 kcal/d, respectively). The 100% substitution of all food and beverage groups combined resulted in a 12.0-point increase in HEI-2005 score and a decrease of 785 kcal/d in total energy intake. Community interventions designed to improve the diet of LMD adults through the use of familiar, healthy food and beverage substitutions have the potential to improve diet quality and decrease energy intake of this health disparate population.",2011-12,13/11/2018 10:47,14/04/2020 08:35,,2191-2197,,12,141,,J Nutr,,,,,,,,eng,,,,,,,PMID: 22031664 PMCID: PMC4584395,,,,"Humans; Adult; Female; Male; Middle Aged; Young Adult; *Diet; *Computer Simulation; Adolescent; Computer Simulation; Cross-Sectional Studies; Energy Intake; Diet; *Energy Intake; *Food, Organic; Beverages; Cluster Analysis; Diet Surveys; Eating; Southeastern United States; 1; Human; Middle Age; Funding Source; Surveys; Adolescence; Cross Sectional Studies; Health Food; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DGWLLKBW,journalArticle,2011,"Adarkwah, Charles Christian; Gandjour, Afschin; Akkerman, Maren; Evers, Silvia M.",Cost-effectiveness of angiotensin-converting enzyme inhibitors for the prevention of diabetic nephropathy in The Netherlands--a Markov model.,PloS one,,1932-6203 1932-6203,10.1371/journal.pone.0026139,,"OBJECTIVE: Type 2 diabetes is the main cause of end-stage renal disease (ESRD) in Europe and the USA. Angiotensin-converting enzyme (ACE) inhibitors have a potential to slow down the progression of renal disease and therefore provide a renal-protective effect. The aim of our study was to assess the most cost-effective time to start an ACE inhibitor (or an angiotensin II receptor blocker [ARB] if coughing as a side effect occurs) in patients with newly diagnosed type 2 diabetes in The Netherlands. METHODS: A lifetime Markov decision model with simulated 50-year-old patients with newly diagnosed diabetes mellitus was developed using published data on costs and health outcomes and simulating the progression of renal disease. A health insurance perspective was adopted. Three strategies were compared: treating all patients at the time of diagnosing type 2 diabetes, screening for microalbuminuria, and screening for macroalbuminuria. RESULTS: In the base-case analysis, the treat-all strategy is associated with the lowest costs and highest benefit and therefore dominates screening both for macroalbuminuria and microalbuminuria. A multivariate sensitivity analysis shows that the probability of savings is 70%. CONCLUSIONS: In The Netherlands for patients with type 2 diabetes prescription of an ACE inhibitor immediately after diagnosis should be considered if they do not have contraindications. An ARB should be considered for those patients developing a dry cough under ACE inhibitor therapy. The potential for cost savings would be even larger if the prevention of cardiovascular events were considered.",2011,13/11/2018 10:47,14/04/2020 08:34,,e26139,,10,6,,PLoS One,,,,,,,,eng,,,,,,,PMID: 22022539 PMCID: PMC3191181,,,,"Humans; Netherlands; Cost-Benefit Analysis; Quality-Adjusted Life Years; *Models, Economic; *Markov Chains; Angiotensin-Converting Enzyme Inhibitors/*economics/*therapeutic use; Diabetic Nephropathies/complications/drug therapy/*economics/*prevention & control; Kidney Failure, Chronic/complications/economics; 00; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NRNRNHYE,journalArticle,2011,"Marottoli, Richard A.; Coughlin, Joseph F.",Walking the tightrope: developing a systems approach to balance safety and mobility for an aging society.,Journal of aging & social policy,,1545-0821 0895-9420,10.1080/08959420.2011.605655,,"In an aging population, safety and mobility are often viewed as being in conflict, when in fact they are two values that must be reflected equally in transportation policy. The challenge for policy makers and for society is to emphasize and optimize both. To achieve this, a comprehensive systems approach to driver health, personal decision-making and planning, community and transportation systems construction, vehicle design, and licensing regulations is needed. Such an approach requires crafting policies based on conceptualizing the issue as a continuum of resources facilitating safety and mobility regardless of driving status. The discussion that follows reviews components of the issue and suggestions for developing a comprehensive approach.",2011-10,13/11/2018 10:47,14/04/2020 08:34,,372-383,,4,23,,J Aging Soc Policy,,,,,,,,eng,,,,,,,PMID: 21985065,,,,"Humans; *Safety; Risk Factors; Aged; Aged, 80 and over; Resource Allocation; Policy Making; Community Health Planning/*organization & administration; Government Regulation; *Automobile Driving/legislation & jurisprudence/standards; *Mobility Limitation; *Transportation/legislation & jurisprudence/methods/standards; Frail Elderly; Geriatric Assessment; Licensure/legislation & jurisprudence; Public Policy; Risk Adjustment; Automobile Driving – Evaluation – In Old Age; Public Policy – Trends; Safety – Evaluation – In Old Age; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7GXPHAEY,journalArticle,2011,"Aggarwal, Rajesh; Darzi, Ara",Simulation to enhance patient safety: why aren't we there yet?,Chest,,1931-3543 0012-3692,10.1378/chest.11-0728,,"The delivery of state-of-the-art medical care is complex, with large numbers of treatment strategies often available to individual patients. It is paramount to ensure that each patient receives optimal treatment in a safe, effective, and timely manner. Evidence suggests that an unacceptably high number of patients currently experience suboptimal care as the result of adverse events and medical error. Simulation-based training reduces medical error, enhances clinical outcomes, and reduces the cost of clinical care. It is surprising that medical simulation is not routinely integrated into the training curricula of all health-care professionals. Simulation enables doctors to practice and hone their technical, communication, decision making, and crisis management skills in a safe and educationally orientated environment. The process can foster the development of interprofessional working skills, leading to enhanced patient outcomes. Selection, credentialing, and revalidation of medical professionals are also possible in a simulation setting, enabling maintenance of standards of practice throughout a medical career. In order for simulation to become a part of the medical curriculum, collaborative efforts are required from academics, physicians, managers, and policy makers alike. Bringing these groups together, while a challenge, can lead to high-level outputs in medical care, which will benefit all.",2011-10,13/11/2018 10:47,14/04/2020 08:34,,854-858,,4,140,,Chest,,,,,,,,eng,,,,,,,PMID: 21972381,,,,"Humans; Outcome Assessment (Health Care); Patient Safety/*standards; Medical Errors/prevention & control; General Surgery/education; Surgery; Education; Computer Simulation/*trends; Curriculum/trends; Education, Medical/methods/*trends; Professional Competence/standards; 1; Treatment Errors – Prevention and Control; Outcome Assessment; Medical; Patient Safety – Standards; Computer Simulation – Trends; Curriculum – Trends; Medical – Trends; Operative – Education; Professional Competence – Standards; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9X4FY5SL,journalArticle,2011,"Sculier, Delphine; Getahun, Haileyesus; Lienhardt, Christian","Improving the prevention, diagnosis and treatment of TB among people living with HIV: the role of operational research.",Journal of the International AIDS Society,,1758-2652 1758-2652,10.1186/1758-2652-14-S1-S5,,"Operational research is necessary to improve the access to and delivery of tuberculosis prevention, diagnosis and treatment interventions for people living with HIV. We conducted an extensive review of the literature and reports from recent expert consultations and research-related meetings organized by the World Health Organization and the Stop TB Partnership to identify a TB/HIV operational research agenda. We present critical operational research questions in a series of key areas: optimizing TB prevention by enhancing the uptake of isoniazid preventive therapy and the implementation of infection control measures; assessing the effectiveness of existing diagnostic tools and scaling up new technologies; improving service delivery models; and reducing risk factors for mortality among TB patients living with HIV. We discuss the potential impact that addressing the operational research questions may have on improving programmes' performance, assessing new strategies or interventions for TB control, or informing global or national policy formulation. Financial resources to implement these operational research questions should be mobilized from existing and new funding mechanisms. National TB and HIV/AIDS programmes should develop their operational research agendas based on these questions, and conduct the research that they consider crucial for improving TB and HIV control in their settings in collaboration with research stakeholders.",06/07/2011,13/11/2018 10:47,14/04/2020 08:35,,S5,,,14 Suppl 1,,J Int AIDS Soc,,,,,,,,eng,,,,,,,PMID: 21967874 PMCID: PMC3194150,,,,Humans; *Operations Research; Animals; Communicable Disease Control/*methods; HIV Infections/*complications; Tuberculosis/complications/*diagnosis/*drug therapy/prevention & control; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KDHV97M7,journalArticle,2012,"Wilson, Charlotte; Alam, Rahul; Latif, Saima; Knighting, Katherine; Williamson, Susan; Beaver, Kinta",Patient access to healthcare services and optimisation of self-management for ethnic minority populations living with diabetes: a systematic review.,Health & social care in the community,,1365-2524 0966-0410,10.1111/j.1365-2524.2011.01017.x,,"A higher risk of diabetes mellitus in South Asian and Black African populations combined with lower reported access and self-management-related health outcomes informed the aims of this study. Our aims were to synthesise and evaluate evidence relating to patient self-management and access to healthcare services for ethnic minority groups living with diabetes. A comprehensive search strategy was developed capturing a full range of study types from 1995-2010, including relevant hand-searched literature pre-dating 1995. Systematic database searches of MEDLINE, Cochrane, DARE, HTA and NHSEED, the British Nursing Index, CAB abstracts, EMBASE, Global Health, Health Management Information Consortium and PsychInfo were conducted, yielding 21,288 abstracts. Following search strategy refinement and the application of review eligibility criteria; 11 randomised controlled trials (RCTs), 18 qualitative studies and 18 quantitative studies were evaluated and principal results extracted. Results suggest that self-management practices are in need of targeted intervention in terms of patients' knowledge and understanding of their illness, inadequacy of information and language and communication difficulties arising from cultural differences. Access to health-care is similarly hindered by a lack of cultural sensitivity in service provision and under use of clinic-based interpreters and community-based services. Recommendations for practice and subsequent intervention primarily rest at the service level but key barriers at patient and provider levels are also identified.",2012-01,13/11/2018 10:47,14/04/2020 08:35,,Jan-19,,1,20,,Health Soc Care Community,,,,,,,,eng,(c) 2011 Blackwell Publishing Ltd.,,,,,,PMID: 21749529,,,,"Humans; Health Services Accessibility; Socioeconomic Factors; United Kingdom; Health Services Accessibility/*organization & administration; United Kingdom/epidemiology; *Self Care; Quality of Health Care/organization & administration; Africa/ethnology; Asia, Western/ethnology; Caribbean Region/ethnology; Cultural Competency; Developed Countries; Diabetes Mellitus/*ethnology/therapy; Ethnic Groups/*statistics & numerical data; Language; Trust; Human; Self Care; Diabetes Mellitus; British Nursing Index; Clinical Assessment Tools; Cochrane Library; Embase; Medline; Minority Groups; Patient Education; Psycinfo; Quality Assessment; Social Work; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UYEUAENJ,journalArticle,2011,"Gest, Scott D.; Osgood, D. Wayne; Feinberg, Mark E.; Bierman, Karen L.; Moody, James",Strengthening prevention program theories and evaluations: contributions from social network analysis.,Prevention science : the official journal of the Society for Prevention Research,,1573-6695 1389-4986,10.1007/s11121-011-0229-2,,"A majority of school-based prevention programs target the modification of setting-level social dynamics, either explicitly (e.g., by changing schools' organizational, cultural or instructional systems that influence children's relationships), or implicitly (e.g., by altering behavioral norms designed to influence children's social affiliations and interactions). Yet, in outcome analyses of these programs, the rich and complicated set of peer network dynamics is often reduced to an aggregation of individual characteristics or assessed with methods that do not account for the interdependencies of network data. In this paper, we present concepts and analytic methods from the field of social network analysis and illustrate their great value to prevention science--both as a source of tools for refining program theories and as methods that enable more sophisticated and focused tests of intervention effects. An additional goal is to inform discussions of the broader implications of social network analysis for public health efforts.",2011-12,13/11/2018 10:47,14/04/2020 08:34,,349-360,,4,12,,Prev Sci,,,,,,,,eng,,,,,,,PMID: 21728069 PMCID: PMC3222146,,,,Humans; *Social Support; Peer Group; Preventive Health Services/*organization & administration; School Health Services/*organization & administration; Support; Psychosocial; Preventive Health Care – Administration; School Health Services – Administration; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, A7LKA2MQ,journalArticle,2011,"Ducher, Gaele; Turner, Anne I.; Kukuljan, Sonja; Pantano, Kathleen J.; Carlson, Jennifer L.; Williams, Nancy I.; De Souza, Mary Jane",Obstacles in the optimization of bone health outcomes in the female athlete triad.,"Sports medicine (Auckland, N.Z.)",,1179-2035 0112-1642,10.2165/11588770-000000000-00000,,"Maintaining low body weight for the sake of performance and aesthetic purposes is a common feature among young girls and women who exercise on a regular basis, including elite, college and high-school athletes, members of fitness centres, and recreational exercisers. High energy expenditure without adequate compensation in energy intake leads to an energy deficiency, which may ultimately affect reproductive function and bone health. The combination of low energy availability, menstrual disturbances and low bone mineral density is referred to as the 'female athlete triad'. Not all athletes seek medical assistance in response to the absence of menstruation for 3 or more months as some believe that long-term amenorrhoea is not harmful. Indeed, many women may not seek medical attention until they sustain a stress fracture. This review investigates current issues, controversies and strategies in the clinical management of bone health concerns related to the female athlete triad. Current recommendations focus on either increasing energy intake or decreasing energy expenditure, as this approach remains the most efficient strategy to prevent further bone health complications. However, convincing the athlete to increase energy availability can be extremely challenging. Oral contraceptive therapy seems to be a common strategy chosen by many physicians to address bone health issues in young women with amenorrhoea, although there is little evidence that this strategy improves bone mineral density in this population. Assessment of bone health itself is difficult due to the limitations of dual-energy X-ray absorptiometry (DXA) to estimate bone strength. Understanding how bone strength is affected by low energy availability, weight gain and resumption of menses requires further investigations using 3-dimensional bone imaging techniques in order to improve the clinical management of the female athlete triad.",01/07/2011,13/11/2018 10:47,14/04/2020 08:34,,587-607,,7,41,,Sports Med,,,,,,,,eng,,,,,,,PMID: 21688870,,,,"Humans; Female; Child; Energy Intake; *Bone Density/drug effects/physiology; Absorptiometry, Photon; Amenorrhea/*complications/*drug therapy; Athletic Performance/*physiology; Bone and Bones/diagnostic imaging/*physiopathology; Bone Density Conservation Agents; Contraceptives, Oral/therapeutic use; Exercise/physiology; Sports; Thinness/*complications; Stress; Adolescence; Attitude to Health; Women's Health; Absorptiometry; Adolescent Development; Amenorrhea; American Academy of Pediatrics – Standards; American College of Sports Medicine – Standards; American Physical Therapy Association – Standards; Athletes – Psychosocial Factors; Biological Markers; Bone Density; Bone Density – Evaluation; Bone Remodeling – Evaluation; Child Development; Contraceptives; Diphosphonates – Therapeutic Use; Energy Metabolism; Estrogens – Therapeutic Use; Female Athlete Triad – Complications; Female Athlete Triad – Therapy; Fractures; Health Knowledge; Magnetic Resonance Imaging; Muscle Strengthening; Oligomenorrhea; Oral – Therapeutic Use; Osteoporosis – Prevention and Control; Photon; Physical Therapist Attitudes; Physician Attitudes; Plyometrics; Recovery; Sports Organizations – Standards; Stress – Preventions; Tomography; Vitamin D Deficiency – Prevention and Control; X-Ray Computed – Methods; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HAMPEDCY,journalArticle,2011,"Mehrotra, Sanjay; Kim, Kibaek",Outcome based state budget allocation for diabetes prevention programs using multi-criteria optimization with robust weights.,Health care management science,,1386-9620 1386-9620,10.1007/s10729-011-9166-7,,"We consider the problem of outcomes based budget allocations to chronic disease prevention programs across the United States (US) to achieve greater geographical healthcare equity. We use Diabetes Prevention and Control Programs (DPCP) by the Center for Disease Control and Prevention (CDC) as an example. We present a multi-criteria robust weighted sum model for such multi-criteria decision making in a group decision setting. The principal component analysis and an inverse linear programming techniques are presented and used to study the actual 2009 budget allocation by CDC. Our results show that the CDC budget allocation process for the DPCPs is not likely model based. In our empirical study, the relative weights for different prevalence and comorbidity factors and the corresponding budgets obtained under different weight regions are discussed. Parametric analysis suggests that money should be allocated to states to promote diabetes education and to increase patient-healthcare provider interactions to reduce disparity across the US.",2011-12,13/11/2018 10:47,14/04/2020 08:34,,324-337,,4,14,,Health Care Manag Sci,,,,,,,,eng,,,,,,,PMID: 21674143,,,,"Humans; Budgets; Health Services Accessibility; United States; Comorbidity; United States/epidemiology; Models, Econometric; Prevalence; Health Promotion/*economics; Diabetes Mellitus/epidemiology/mortality/*prevention & control; Health Care Rationing/methods/*statistics & numerical data; Healthcare Disparities/ethnology/*statistics & numerical data; Principal Component Analysis; Models; Statistical; Diabetes Mellitus – Prevention and Control; Diabetes Mellitus – Mortality; Diabetes Mellitus – Epidemiology; Factor Analysis; Health Promotion – Economics; Health Resource Allocation – Methods; Health Resource Allocation – Statistics and Numerical Data; Health Services Accessibility – Statistics and Numerical Data; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, R87PFB54,journalArticle,2011,"Zhang, Ting; Lu, Jun; Li, Li-Ming",[Application of sociocentric network analysis in public health].,Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi,,0254-6450 0254-6450,,,,2011-04,13/11/2018 10:47,14/04/2020 08:35,,416-418,,4,32,,Zhonghua Liu Xing Bing Xue Za Zhi,,,,,,,,chi,,,,,,,PMID: 21569678,,,,Humans; *Public Health; *Community Networks; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JDG3WHYC,journalArticle,2011,"Maglio, Paul P.; Mabry, Patricia L.",Agent-based models and systems science approaches to public health.,American journal of preventive medicine,,1873-2607 0749-3797,10.1016/j.amepre.2010.11.010,,,2011-03,13/11/2018 10:47,14/04/2020 08:34,,392-394,,3,40,,Am J Prev Med,,,,,,,,eng,,,,,,,PMID: 21335277 PMCID: PMC3061834,,,,"*Health Policy; Humans; *Models, Statistical; *Computer Simulation; Policy Making; Preventive Medicine/methods; Public Health/methods; 1; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HAPT4VNM,journalArticle,2011,"Peyre, Hugo; Leplege, Alain; Coste, Joel","Missing data methods for dealing with missing items in quality of life questionnaires. A comparison by simulation of personal mean score, full information maximum likelihood, multiple imputation, and hot deck techniques applied to the SF-36 in the French 2003 decennial health survey.","Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation",,1573-2649 0962-9343,10.1007/s11136-010-9740-3,,"PURPOSE: Missing items are common in quality of life (QoL) questionnaires and present a challenge for research in this field. It remains unclear which of the various methods proposed to deal with missing data performs best in this context. We compared personal mean score, full information maximum likelihood, multiple imputation, and hot deck techniques using various realistic simulation scenarios of item missingness in QoL questionnaires constructed within the framework of classical test theory. METHODS: Samples of 300 and 1,000 subjects were randomly drawn from the 2003 INSEE Decennial Health Survey (of 23,018 subjects representative of the French population and having completed the SF-36) and various patterns of missing data were generated according to three different item non-response rates (3, 6, and 9%) and three types of missing data (Little and Rubin's ""missing completely at random,"" ""missing at random,"" and ""missing not at random""). The missing data methods were evaluated in terms of accuracy and precision for the analysis of one descriptive and one association parameter for three different scales of the SF-36. RESULTS: For all item non-response rates and types of missing data, multiple imputation and full information maximum likelihood appeared superior to the personal mean score and especially to hot deck in terms of accuracy and precision; however, the use of personal mean score was associated with insignificant bias (relative bias <2%) in all studied situations. CONCLUSIONS: Whereas multiple imputation and full information maximum likelihood are confirmed as reference methods, the personal mean score appears nonetheless appropriate for dealing with items missing from completed SF-36 questionnaires in most situations of routine use. These results can reasonably be extended to other questionnaires constructed according to classical test theory.",2011-03,13/11/2018 10:47,14/04/2020 08:35,,287-300,,2,20,,Qual Life Res,,,,,,,,eng,,,,,,,PMID: 20882358,,,,"France; Humans; Surveys and Questionnaires; Female; Male; Quality of Life; *Quality of Life; Data Interpretation, Statistical; Probability; *Bias; Health Surveys/*instrumentation/*statistics & numerical data; Likelihood Functions; Human; Comparative Studies; Evaluation Research; Multicenter Studies; Validation Studies; Statistical; Data Analysis; Surveys; Bias (Research); Short Form-36 Health Survey (SF-36); Surveys – Equipment and Supplies; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2QCQKN4E,journalArticle,2010,"Yu, Junhua; Smith, Kenneth J.; Brixner, Diana I.",Cost effectiveness of pharmacotherapy for the prevention of migraine: a Markov model application.,CNS drugs,,1179-1934 1172-7047,10.2165/11531180-000000000-00000,,"BACKGROUND: There are few data about the cost effectiveness of prophylactic medications for migraine. Clinical trials have shown several preventive agents to be useful in reducing the frequency of migraine attack while having tolerable side effects. OBJECTIVE: To compare the cost effectiveness of adding preventive treatment to abortive therapy for acute migraine with abortive therapy for acute migraine alone in the primary care setting. METHODS: A Markov decision analytic model with a cycle length of 1 day, a time horizon of 365 days and three health states was used to perform an analysis comparing the cost effectiveness and utility of five treatments for migraine prophylaxis (amitriptyline 75 mg/day, topiramate 100 and 200 mg/day, timolol 20 mg/day, divalproex sodium 1000 mg/day or propranolol 160 mg/day) with treatment of acute migraine alone for the management of migraine in the primary care setting. One-way and probabilistic sensitivity analyses were performed to test the robustness of the results. RESULTS: The expected total annual cost for the use of preventive agents ranged from $US2932 to $US3887, compared with $US3960 for the use of abortive medications only. In the baseline analysis, use of each of the five preventive agents generated more quality-adjusted life-years (QALYs) and incurred lower costs compared with abortive medications only. Monte Carlo Simulation suggested that amitriptyline 75 mg/day was most likely to be considered a cost-effective option versus the other five therapies, followed by timolol 20 mg/day, topiramate 200 mg/day, topiramate 100 mg/day, divalproex sodium 1000 mg/day and propranolol 160 mg/day when the willingness-to-pay (WTP) for society is <$US18 000 per QALY gained. CONCLUSIONS: Preventive medications appear to be a cost-effective approach to the management of migraine in the primary care setting compared with the approach of abortive treatment only. Among those preventive agents, probabilistic sensitivity analysis suggests that, when the societal WTP is <$US18 000 per QALY gained, amitriptyline 75 mg/day is most likely to be considered a cost-effective option.",2010-08,13/11/2018 10:47,14/04/2020 08:35,,695-712,,8,24,,CNS Drugs,,,,,,,,eng,,,,,,,PMID: 20658800,,,,"Humans; Antidepressive Agents; Cost-Benefit Analysis; Treatment Outcome; Female; Male; Markov Chains; Health Status; Probability; Adrenergic beta-Antagonists/adverse effects/economics/pharmacology/*therapeutic use; Antidepressive Agents, Tricyclic/adverse effects/economics/pharmacology/*therapeutic use; Economics, Pharmaceutical; Migraine Disorders/drug therapy/economics/*prevention & control; Neuroprotective Agents/adverse effects/economics/pharmacology/*therapeutic use; 1; Human; Cost Benefit Analysis; Treatment Outcomes; Adrenergic Beta-Antagonists – Adverse Effects; Adrenergic Beta-Antagonists – Economics; Adrenergic Beta-Antagonists – Pharmacodynamics; Adrenergic Beta-Antagonists – Therapeutic Use; Economics; Migraine – Drug Therapy; Migraine – Economics; Migraine – Prevention and Control; Neuroprotective Agents – Adverse Effects; Neuroprotective Agents – Economics; Neuroprotective Agents – Pharmacodynamics; Neuroprotective Agents – Therapeutic Use; Pharmaceutical; Tricyclic – Adverse Effects; Tricyclic – Economics; Tricyclic – Pharmacodynamics; Tricyclic – Therapeutic Use; Markov; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VXY84JWH,journalArticle,2010,"Kort, Rodney","5th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention: summary of key research and implications for policy and practice - operations research.",Journal of the International AIDS Society,,1758-2652 1758-2652,10.1186/1758-2652-13-S1-S5,,"Operations research was added as a fourth scientific track to the pathogenesis conference series at the 5th IAS Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2009) in recognition of the importance of this growing research field and the need for applied research to inform and evaluate the scale up of some key interventions in HIV treatment, care and prevention.Several studies demonstrated how task shifting and the decentralization of health services can leverage scarce health care resources to support scale-up efforts. For example, a Ugandan study comparing home-based and facility-based antiretroviral therapy (ART) delivery found that both delivered equivalent clinical outcomes, but home-based delivery resulted in substantial cost savings to patients; and a retrospective cohort analysis of an HIV care programme in Lesotho demonstrated that devolving routine patient management to nurses and trained counsellors resulted in impressive gains in annual enrolment, retention in care and other clinical indicators.Studies also demonstrated how the use of trained counsellors and public health advisors could effectively expand both clinical and public health capacity in low-income settings. Studies evaluating the impact of integrating HIV and TB care resulted in improved treatment outcomes in coinfected populations, the development of environmental interventions to reduce TB transmission, and uncovering of the extent of multi-drug-resistant and extremely drug-resistant tuberculosis (MDR-TB and XDR-TB) in KwaZulu-Natal, South Africa.Some mathematical modelling and cost-effectiveness studies presented at this meeting addressed interventions to increase retention in care, and strengthened the evidentiary basis for universal voluntary testing and immediate ART on reducing HIV transmission; debate continued about the relative merits of clinical versus laboratory monitoring. Finally, a provocative plenary presentation outlined the shortfalls of current prevention interventions and argued for more cost-effectiveness analyses to guide the selection of interventions for maximum benefit.",01/06/2010,13/11/2018 10:47,14/04/2020 08:34,,S5,,,13 Suppl 1,,J Int AIDS Soc,,,,,,,,eng,,,,,,,PMID: 20519026 PMCID: PMC2880256,,,,Humans; Anti-HIV Agents/therapeutic use; Health Services/economics; HIV Infections/drug therapy/*economics/prevention & control; Laboratories/economics; Tuberculosis/epidemiology/transmission; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QWKUGISY,journalArticle,2009,"Tomblin Murphy, Gail; MacKenzie, Adrian; Alder, Robert; Birch, Stephen; Kephart, George; O'Brien-Pallas, Linda",An applied simulation model for estimating the supply of and requirements for registered nurses based on population health needs.,"Policy, politics & nursing practice",,1552-7468 1527-1544,10.1177/1527154409358777,,"Aging populations, limited budgets, changing public expectations, new technologies, and the emergence of new diseases create challenges for health care systems as ways to meet needs and protect, promote, and restore health are considered. Traditional planning methods for the professionals required to provide these services have given little consideration to changes in the needs of the populations they serve or to changes in the amount/types of services offered and the way they are delivered. In the absence of dynamic planning models that simulate alternative policies and test policy mixes for their relative effectiveness, planners have tended to rely on projecting prevailing or arbitrarily determined target provider-population ratios. A simulation model has been developed that addresses each of these shortcomings by simultaneously estimating the supply of and requirements for registered nurses based on the identification and interaction of the determinants. The model's use is illustrated using data for Nova Scotia, Canada.",2009-11,13/11/2018 10:47,14/04/2020 08:34,,240-251,,4,10,,Policy Polit Nurs Pract,,,,,,,,eng,,,,,,,PMID: 20164064,,,,"Humans; Forecasting; *Computer Simulation; Policy Making; System dynamics; Education, Nursing; *Planning Techniques; Nova Scotia; Nursing Staff/supply & distribution; Nursing/*manpower; Personnel Management; 1; ****; 310",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7KE45DUF,journalArticle,2010,"van Walbeek, Corne",A simulation model to predict the fiscal and public health impact of a change in cigarette excise taxes.,Tobacco control,,1468-3318 0964-4563,10.1136/tc.2008.028779,,"OBJECTIVES: (1) To present a model that predicts changes in cigarette consumption and excise revenue in response to excise tax changes, and (2) to demonstrate that, if the industry has market power, increases in specific taxes have better tobacco control consequences than increases in ad valorem taxes. DESIGN: All model parameters are user-determined. The model calculates likely changes in cigarette consumption, smoking prevalence and excise tax revenues due to an excise tax change. The model is applicable to countries that levy excise tax as specific or ad valorem taxes. RESULTS: For a representative low-income or middle-income country a 20% excise tax increase decreases cigarette consumption and industry revenue by 5% and increases excise tax revenues by 14%, if there is no change in the net-of-tax price. If the excise tax is levied as a specific tax, the industry has an incentive to raise the net-of-tax price, enhancing the consumption-reducing impact of the tax increase. If the excise tax is levied as an ad valorem tax, the industry has no such incentive. The industry has an incentive to reduce the net-of-tax price in response to an ad valorem excise tax increase, undermining the public health and fiscal benefits of the tax increase. CONCLUSIONS: This paper presents a simple web-based tool that allows policy makers and tobacco control advocates to estimate the likely consumption, fiscal and mortality impacts of a change in the cigarette excise tax. If a country wishes to reduce cigarette consumption by increasing the excise tax, a specific tax structure is better than an ad valorem tax structure.",2010-02,13/11/2018 10:47,14/04/2020 08:35,,31-36,,1,19,,Tob Control,,,,,,,,eng,,,,,,,PMID: 19850550,,,,"Humans; Computer Simulation; Policy Making; Motivation; *Models, Econometric; Health Policy/economics; Internet; Public Health/economics/legislation & jurisprudence; Smoking Cessation/economics/methods; Smoking Prevention; Smoking/*economics; Taxes/*economics; Tobacco Industry/economics; 1; Human; Funding Source; Developing Countries; Behavioral Changes; Predictive Validity; Consumer Advocacy; Economic Competition; Income; Industry; Sellers and Selling; Smoking; Smoking – Mortality; Taxes – Classification; Taxes – Developing Countries; Theory Construction; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5M5IB9SM,journalArticle,2009,"Chahed, Salma; Marcon, Eric; Sahin, Evren; Feillet, Dominique; Dallery, Yves",Exploring new operational research opportunities within the Home Care context: the chemotherapy at home.,Health care management science,,1386-9620 1386-9620,,,"Home Care (HC) services provide complex and coordinated medical and paramedical care to patients at their homes. As health care services move into the home setting, the need for developing innovative approaches that improve the efficiency of home care organizations increases. We first conduct a literature review of investigations dealing with operation planning within the area of home care management. We then address a particular issue dealing with the planning of operations related to chemotherapy at home as it is an emergent problem in the French context. Our interest is focused on issues specific to the anti-cancer drug supply chain. We identify various models that can be developed and analyze one of them.",2009-06,13/11/2018 10:47,14/04/2020 08:34,,179-191,,2,12,,Health Care Manag Sci,,,,,,,,eng,,,,,,,PMID: 19469457,,,,"Humans; Systems Analysis; Models, Theoretical; *Operations Research; Efficiency, Organizational; Antineoplastic Agents/*administration & dosage/therapeutic use; Home Care Services/*organization & administration; Neoplasms/drug therapy; Pharmaceutical Services/organization & administration; Models; Theoretical; Organizational Efficiency; Neoplasms – Drug Therapy; Antineoplastic Agents – Administration and Dosage; Antineoplastic Agents – Therapeutic Use; Home Health Care – Administration; Pharmacy Service – Administration; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Y8T7F9FA,journalArticle,2009,"Tunes-da-Silva, Gisela; Pedroso-de-Lima, Antonio C.; Sen, Pranab K.",A semi-Markov multistate model for estimation of the mean quality-adjusted survival for non-progressive processes.,Lifetime data analysis,,1572-9249 1380-7870,10.1007/s10985-008-9106-0,,"We discuss the estimation of the expected value of the quality-adjusted survival, based on multistate models. We generalize an earlier work, considering the sojourn times in health states are not identically distributed, for a given vector of covariates. Approaches based on semiparametric and parametric (exponential and Weibull distributions) methodologies are considered. A simulation study is conducted to evaluate the performance of the proposed estimator and the jackknife resampling method is used to estimate the variance of such estimator. An application to a real data set is also included.",2009-06,13/11/2018 10:47,14/04/2020 08:35,,216-240,,2,15,,Lifetime Data Anal,,,,,,,,eng,,,,,,,PMID: 19082710,,,,"Humans; *Models, Statistical; Quality of Life; *Markov Chains; Proportional Hazards Models; *Survival Analysis; Probability; Kaplan-Meier Estimate; Likelihood Functions; Biometry; Brazil; Hospitalization/statistics & numerical data; Methods***; Human; Models; Statistical; Biometrics; Cox Proportional Hazards Model; Hospitalization – Statistics and Numerical Data; Kaplan-Meier Estimator; Survival Analysis; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DWPZ5GAC,journalArticle,2008,"Rogoza, Raina M.; Ferko, Nicole; Bentley, James; Meijer, Chris J. L. M.; Berkhof, Johannes; Wang, Kung-Liahng; Downs, Levi; Smith, Jennifer S.; Franco, Eduardo L.",Optimization of primary and secondary cervical cancer prevention strategies in an era of cervical cancer vaccination: a multi-regional health economic analysis.,Vaccine,,0264-410X 0264-410X,10.1016/j.vaccine.2008.02.039,,"With the recent advent of cervical cancer vaccines, many questions relating to the best overall prevention methods for cervical disease are beginning to arise. A Markov model was used across five geographic regions (Canada, The Netherlands, Taiwan, UK, US) to examine the clinical benefits and cost-effectiveness of: (1) vaccination combined with screening, considering changes to screening-related parameters and (2) vaccination combined with screening, considering changes to screening policy. Given the assumptions used in this analysis, adding vaccination to current screening is likely to be cost-effective in the regions studied. When considering vaccination with several plausible changes to screening programmes, locations with the most frequent Papanicolaou smear testing may achieve the most efficiency gains by adopting a less frequent screening interval or incorporating HPV testing into their screening practices. Although it may be beneficial to change screening to maximize efficiency, the most cost-effective strategies for vaccination and screening combinations may not lead to the greatest reductions in cervical cancer; therefore such policy decisions may vary depending on region-specific goals. Finally, new screening paradigms such as primary HPV testing should be considered in future analyses.",15/09/2008,13/11/2018 10:47,14/04/2020 08:35,,F46-58,,,26 Suppl 5,,Vaccine,,,,,,,,eng,,,,,,,PMID: 18992382,,,,"Humans; Female; *Models, Econometric; Papillomavirus Infections/*economics/*prevention & control; Uterine Cervical Neoplasms/*economics/*prevention & control; Vaccination/*economics; 1; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, C8PTXIVA,journalArticle,2008,"Mabry, Patricia L.; Olster, Deborah H.; Morgan, Glen D.; Abrams, David B.",Interdisciplinarity and systems science to improve population health: a view from the NIH Office of Behavioral and Social Sciences Research.,American journal of preventive medicine,,0749-3797 0749-3797,10.1016/j.amepre.2008.05.018,,"Fueled by the rapid pace of discovery, humankind's ability to understand the ultimate causes of preventable common disease burdens and to identify solutions is now reaching a revolutionary tipping point. Achieving optimal health and well-being for all members of society lies as much in the understanding of the factors identified by the behavioral, social, and public health sciences as by the biological ones. Accumulating advances in mathematical modeling, informatics, imaging, sensor technology, and communication tools have stimulated several converging trends in science: an emerging understanding of epigenomic regulation; dramatic successes in achieving population health-behavior changes; and improved scientific rigor in behavioral, social, and economic sciences. Fostering stronger interdisciplinary partnerships to bring together the behavioral-social-ecologic models of multilevel ""causes of the causes"" and the molecular, cellular, and, ultimately, physiological bases of health and disease will facilitate breakthroughs to improve the public's health. The strategic vision of the Office of Behavioral and Social Sciences Research (OBSSR) at the National Institutes of Health (NIH) is rooted in a collaborative approach to addressing the complex and multidimensional issues that challenge the public's health. This paper describes OBSSR's four key programmatic directions (next-generation basic science, interdisciplinary research, systems science, and a problem-based focus for population impact) to illustrate how interdisciplinary and transdisciplinary perspectives can foster the vertical integration of research among biological, behavioral, social, and population levels of analysis over the lifespan and across generations. Interdisciplinary and multilevel approaches are critical both to the OBSSR's mission of integrating behavioral and social sciences more fully into the NIH scientific enterprise and to the overall NIH mission of utilizing science in the pursuit of fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to extend healthy life and reduce the burdens of illness and disability.",2008-08,13/11/2018 10:47,14/04/2020 08:34,,S211-224,,2 Suppl,35,,Am J Prev Med,,,,,,,,eng,,,,,,,PMID: 18619402 PMCID: PMC2587290,,,,Humans; United States; Interprofessional Relations; Public Health/*methods; *Interdisciplinary Communication; Systems Theory; *Systems Theory; Science; Organizational Objectives; Behavioral Medicine/organization & administration; Behavioral Research; National Institutes of Health (U.S.)/organization & administration; Science/*methods/organization & administration/trends; Social Sciences/organization & administration; Human; Behavioral Sciences; Public Health – Methods; National Institutes of Health (U.S.) – Administration; Science – Methods; Science – Trends; Social Sciences; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MCBZGWMY,journalArticle,2007,"Bonmarin, I.; Levy-Bruhl, D.",[Contribution of simulation models to public health decisions: the influenza pandemic].,Medecine et maladies infectieuses,,0399-077X 0399-077X,10.1016/j.medmal.2007.02.004,,"The influenza pandemic threat had led to an increased awareness and several countries have used models to assess the impact of control measures on the influenza pandemic. We reviewed the publications related to simulation models since 2003 and discuss their contribution to public health decision in France. The studies conclude that rapid control measures with a high coverage can stop a nascent pandemic. This can be applied to a community with a limited importation of cases but the quantity of antiviral drug needed would become rapidly prohibitive in case of further multiple foci. Both prophylactic and curative use of antiviral drugs can reduce the number of hospitalizations and the incidence during a pandemic. Finally, if a single strategy is sufficient to limit an outbreak in case of a moderate reproductive number, a combination of control measures is mandatory in case of highly transmissible strains. The results of these studies were taken in account to implement guidelines concerning antiviral drug use, in France.",2007-12,13/11/2018 10:47,14/04/2020 08:34,,S204-209,,,37 Suppl 3,,Med Mal Infect,,,,,,,,fre,,,,,,,PMID: 18031963,,,,"France; Humans; *Public Health; *Models, Statistical; *Disease Outbreaks; Influenza, Human/epidemiology/*prevention & control; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YZPFFP6H,journalArticle,2006,"Hunt, Elizabeth A.; Nelson, Kristen L.; Shilkofski, Nicole A.",Simulation in medicine: addressing patient safety and improving the interface between healthcare providers and medical technology.,Biomedical instrumentation & technology,,0899-8205 0899-8205,,,"Medicine, as an industry in which human lives depend on the skill and performance of operators, must create and maintain a culture of safety, in addition to promoting the design of systems to mitigate errors. The use of medical simulation as a mechanism for training healthcare professionals in a safe environment is expanding rapidly. An important component of systems that ensure the safety of patients in the hospital setting is the interface between humans and technology in the hospital. The objective of this paper is to review: (1) the definition and a brief history of medical simulation, (2) examples of how current medical simulation centers are using simulation to address patient safety, and (3) examples of how simulation can be used to enhance patient safety through improvement of the interface between healthcare practitioners and medical technology. Medical simulation and human factors engineering can be used to examine and enhance the interface between healthcare practitioners and medical technology, with the potential to make a significant contribution to patient safety.",2006-10,13/11/2018 10:47,14/04/2020 08:34,,399-404,,5,40,,Biomed Instrum Technol,,,,,,,,eng,,,,,,,PMID: 17078376,,,,Humans; United States; Medical Errors/prevention & control; Patient Safety; *Computer Simulation; Computer Simulation; Communication; *Communication; Health Personnel/*education; *Safety Management; Technology; User-Computer Interface; *Biomedical Technology; 1; Treatment Errors – Prevention and Control; Health Personnel – Education; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NX3SEJHU,journalArticle,2006,"Powell, Stephen M.",Creating a systems approach to patient safety through better teamwork.,Biomedical instrumentation & technology,,0899-8205 0899-8205,,,"Using a systems engineering approach for the delivery of safe, reliable, consistently high quality healthcare is possible, based on the successes in other industries. To realize the level of reengineering required in healthcare, teams must function across disciplines and departments as a unified organization. By creating and maintaining HRTs, existing hierarchies will flatten and HROs will become part of the healthcare delivery system. The organization must support these teams with the proper tools, technology, and culture in order for the HRTs to complete their patient care missions successfully, consistently, efficiently, and most of all, safely. Government/compliance agencies must partner with organizations for the systems engineering approach to succeed in healthcare, so that policy ultimately originates from the consumer/patient through the care team and the organization, as opposed to a top-down mandate.",2006-06,13/11/2018 10:47,14/04/2020 08:35,,205-207,,3,40,,Biomed Instrum Technol,,,,,,,,eng,,,,,,,PMID: 16796325,,,,"Humans; *Quality Assurance, Health Care; Quality of Health Care; Delivery of Health Care; Medical Errors/prevention & control; Patient Safety; Systems Analysis; Quality Improvement; Teamwork; Hospital Administration; *Safety Management; *Organizational Innovation; Organizational Culture; Total Quality Management; Institutional Management Teams; 1; Health Care Delivery; Treatment Errors – Prevention and Control; Organizational Change; Health Facility Administration; Quality Assurance; Health Care Industry; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YJG4YRSY,journalArticle,2005,"Merrill, Jacqueline; Bakken, Suzanne; Caldwell, Michael; Carley, Kathleen; Rockoff, Maxine",Applying organizational network analysis techniques to study information use in a public health agency.,AMIA ... Annual Symposium proceedings. AMIA Symposium,,1942-597X 1559-4076,,,"We are applying organizational network analysis to explore information use in a public health department. The technique is grounded in social science theory, and employs calculations derived from graph theory to generate statistical and graphical models from relational data matrices. For this pilot we will develop network models to characterize how information use in routine work contributes to the agency's performance goals. This is the first step in ongoing work that will extend network analysis with computational methods, to predict the potential effects that improving information use has on the agency's performance.",2005,13/11/2018 10:47,14/04/2020 08:34,,1052,,,,,AMIA Annu Symp Proc,,,,,,,,eng,,,,,,,PMID: 16779339 PMCID: PMC1560595,,,,Humans; Pilot Projects; Operations Research; Organizational Culture; Information Dissemination; *Public Health Administration; *Public Health Informatics; Information Theory; 1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NGU6JKXF,journalArticle,2005,"Hutwagner, L. C.; Thompson, W. W.; Seeman, G. M.; Treadwell, T.",A simulation model for assessing aberration detection methods used in public health surveillance for systems with limited baselines.,Statistics in medicine,,0277-6715 0277-6715,10.1002/sim.2034,,"Public health officials continue to develop and implement new types of ongoing surveillance systems in an attempt to detect aberrations in surveillance data as early as possible. In public health surveillance, aberrations are traditionally defined as an observed value being greater than an expected historical value for that same time period. To account for seasonality, traditional aberration detection methods use three or more years of baseline data across the same time period to calculate the expected historical value. Due to the recent implementation of short-term bioterrorism surveillance systems, many of the new surveillance systems have limited historical data from which to calculate an expected baseline value. Three limited baseline aberration detection methods,",28/02/2005,13/11/2018 10:47,14/04/2020 08:34,,543-550,,4,24,,Stat Med,,,,,,,,eng,"Copyright 2005 John Wiley & Sons, Ltd.",,,,,,PMID: 15678442,"

Symposium on Statistical Methods -Study Design and Decision-Making in Public Health, Atlanta, GA, JAN 27-29, 2003

",,,"Humans; United States; *Models, Statistical; Computer Simulation; Centers for Disease Control and Prevention (U.S.); *Disease Outbreaks; Sensitivity and Specificity; Population Surveillance/*methods; False Positive Reactions; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, L468E7ZH,journalArticle,2004,"Wieman, Thomas Jeffery; Wieman, Eric Andrew",A systems approach to error prevention in medicine.,Journal of surgical oncology,,0022-4790 0022-4790,10.1002/jso.20121,,"Minimization of medical errors is at the core of all clinical medical practices. The first tenet of care is to do no harm. The enormous complexity of modern medical care has made error detection and management extremely difficult. Traditional deterministic methods of solving the ""error issue"" cannot cope with the huge number of potential errors that are possible. Systems thinking and approach to error reduction provides a different avenue for tackling this challenging dilemma. The intent of this article is to introduce a systems view of medical errors and to explain how it can provide new insights about dealing with massively complex organizations such as the healthcare system. Important features include an understanding of system relationships, sources of error, human components, optimization versus perfection in systems and the interrelationships between human and system processes.",01/12/2004,13/11/2018 10:47,14/04/2020 08:35,,115-121,,3,88,,J Surg Oncol,,,,,,,,eng,,,,,,,PMID: 15562464,,,,Delivery of Health Care/*organization & administration; Humans; *Systems Analysis; Process Assessment (Health Care); Medical Errors/*prevention & control; *Problem Solving; Organizational Innovation; Total Quality Management; Risk Management; 1; *****; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HN78PM6X,journalArticle,2003,"Stuart, Bruce; Singhal, Puneet K.; Magder, Laurence S.; Zuckerman, Ilene H.",How robust are health plan quality indicators to data loss? A Monte Carlo simulation study of pediatric asthma treatment.,Health services research,,0017-9124 0017-9124,,,"OBJECTIVES: (1) To test the robustness of a health plan quality indicator (QI) for persistent asthma to various forms of data loss and (2) to assess the implications of the findings for other health plan quality measures. DATA SOURCES/STUDY SETTINGS: Maryland Medicaid fee-for-service (FFS) claims. Children with asthma (n = 5,804) were selected from Medicaid enrollment records and medical and pharmacy FFS claims filed between June 1996 and December 1997. STUDY DESIGN: A variant of a HEDIS measure for treatment of persistent asthma (the percent of asthma patients filling two or more rescue medications who also filled a controller medication) was selected to test the robustness of proportion-based QIs to loss of data. Data loss was simulated through a series of Monte Carlo experiments. DATA COLLECTION/EXTRACTION METHODS: Merged FFS medical and prescription claims. PRINCIPAL FINDINGS: The asthma QI measure was highly robust to systematic and random data loss. The measure declined by less than 2 percent in the presence of up to a 35 percent data loss. Redundancy in the numerator of the QI significantly increased the robustness of the measure to data loss. CONCLUSIONS: A HEDIS-related QI measure for persistent asthma is robust to data loss. The findings suggest that other proportion-based quality indicators, particularly those in which plan members have multiple opportunities to meet the numerator criterion, are likely to reflect true levels of health plan quality in the face of incomplete data capture.",2003-12,13/11/2018 10:47,14/04/2020 08:35,,1547-1561,,6 Pt 1,38,,Health Serv Res,,,,,,,,eng,,,,,,,PMID: 14727787 PMCID: PMC1360963,,,,"Humans; *Quality Indicators, Health Care; United States; Health Services Research; Quality of Health Care; Child; Adolescent; Computer Simulation; Research Design; Child, Preschool; *Monte Carlo Method; Asthma/*therapy; Fee-for-Service Plans/*standards; Health Benefit Plans, Employee/standards; Health Services Research/methods/statistics & numerical data; Maryland; Medicaid/*standards; State Health Plans/standards; Human; Clinical Indicators; Funding Source; Statistical; Data Analysis; Adolescence; Health Services Research – Methods; Bias (Research); Asthma – Therapy – In Infancy and Childhood; Preschool; Asthma – Drug Therapy; Fee for Service Plans; Health Plan Employer Data and Information Set; Medicaid – Standards; Performance Measurement Systems – Methods; Research Measurement – Methods; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9HQWVVL9,journalArticle,2003,"Israr, S. M.",Is Ministry of Health fully prepared to implement an effective DOTS program in Pakistan? An operations research on TB control program in the public health sector in Sindh.,JPMA. The Journal of the Pakistan Medical Association,,0030-9982 0030-9982,,,"PURPOSE OF THE STUDY: Pakistan is among the high-burden countries for tuberculosis. One of the fundamental problems in TB control is a high defaulter rate among the registered TB cases in the public sector. In 1999, a cross-sectional study was designed to identify the determinants of low compliance for the TB treatment in two rural districts in Sindh. METHODS: Before the actual data collection, a pilot testing was planned in a secondary level care hospital. Fourteen defaulters for TB treatment were identified but none could be contacted due to incomplete addresses. Other alternatives were explored with the health facility team to reach them including a field-based search through Lady Health Workers of the National Health Program but all endeavors went into vain. The pilot testing propelled us to postpone the cross-sectional study but we continued scrutinizing the follow up problem for TB patients in other health facilities. Not surprisingly, more or less a similar picture was found in those health facilities. PRINCIPAL CONCLUSIONS: The study concludes that the public health care system in Pakistan lacks even the basic requirements for an effective TB control program, that is, a viable information system and the functional integration of program with rest of the health care delivery system. A DOTS strategy to control TB was initiated in the public sector in Pakistan just one year prior to this study. The Ministry of Health requires re-visiting the program to ensure that the lacunae identified in this study are being taken care of in the current DOTS strategy.",2003-08,13/11/2018 10:47,14/04/2020 08:34,,324-327,,8,53,,J Pak Med Assoc,,,,,,,,eng,,,,,,,PMID: 14558734,,,,"Humans; Delivery of Health Care; Pilot Projects; Cross-Sectional Studies; Public Health Administration/*standards; *Directly Observed Therapy; Communicable Disease Control/*organization & administration; Government Programs; Pakistan/epidemiology; Patient Dropouts/*statistics & numerical data; Tuberculosis, Pulmonary/drug therapy/epidemiology/*prevention & control; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FT9MWVDN,journalArticle,2003,"Hahl, Jarmo; Simell, Tuula; Kupila, Antti; Keskinen, Paivi; Knip, Mikael; Ilonen, Jorma; Simell, Olli",A simulation model for estimating direct costs of type 1 diabetes prevention.,PharmacoEconomics,,1170-7690 1170-7690,10.2165/00019053-200321050-00001,,"BACKGROUND: The ongoing Type 1 Diabetes Prediction and Prevention Project in Finland (DIPP) is based on screening of genetic type 1 diabetes mellitus susceptibility, subsequent autoantibody follow-up and experimental preventive treatment with nasal insulin. OBJECTIVE: To analyse direct costs of type 1 diabetes prevention therapy with nasal insulin as it is now being studied in the DIPP project, and as it might be used as a part of routine healthcare in Finland. DATA AND METHODS: For the purposes of cost analysis, two different diabetes prevention models were constructed. The research-oriented model followed accurately the DIPP protocol and the practice-oriented model was based on the estimates of a panel of experts on how the prevention would be conducted as a part of the routine healthcare in Finland. To take into account the uncertainty and variability attached to the use of resources, a Monte Carlo simulation model was utilised. The costs of the two models comprising 500 iterations each were simulated using the Monte Carlo model. STUDY PERSPECTIVE: This study was performed from the healthcare provider's viewpoint. RESULTS: The total direct costs per person of the research-oriented model were 2102 and 1676 euros (EUR) in the first and second year and those of the practice-oriented model EUR827 and EUR675, respectively (EUR1 approximately dollars US1.1; 2002 values). Subsequently, the costs rose only as a result of the increased use of insulin as the children grew older. After the 15th year, when the age structure of the population in the study had stabilised, the annual direct costs per person were EUR1798 (research-oriented model) and EUR797 (practice-oriented model). CONCLUSIONS: The costs of prevention with nasal insulin are low when compared with estimates of the annual healthcare costs of type 1 diabetes. This study suggests, with some critical assumptions (in particular, that nasal insulin is effective in the prevention of type I diabetes), that a 2 to 3-year delay in the disease onset may make prevention according to the practice-oriented model cost saving.",2003,13/11/2018 10:47,14/04/2020 08:34,,295-303,,5,21,,Pharmacoeconomics,,,,,,,,eng,,,,,,,PMID: 12627983,,,,"Humans; Forecasting; Follow-Up Studies; Monte Carlo Method; Computer Simulation; Health Expenditures; Models, Economic; Finland; Administration, Intranasal; Diabetes Mellitus, Type 1/*economics/*prevention & control; Hypoglycemic Agents/administration & dosage/economics/therapeutic use; Insulin/administration & dosage/economics/therapeutic use; 1; 310",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Y5EM5BED,journalArticle,2002,"Womer, Richard B.; Tracy, Ellen; Soo-Hoo, Winson; Bickert, Betsy; DiTaranto, Susan; Barnsteiner, Jane H.",Multidisciplinary systems approach to chemotherapy safety: rebuilding processes and holding the gains.,Journal of clinical oncology : official journal of the American Society of Clinical Oncology,,0732-183X 0732-183X,10.1200/JCO.2002.04.108,,"PURPOSE: The problem of medication safety came to public attention largely through a chemotherapy error, and the high toxicity and low therapeutic index of anticancer medications make safety in their prescription and administration critical. We have undertaken a thorough revision of our systems for inpatient chemotherapy. METHODS: We participated in a multi-institutional collaborative effort of the Institute for Healthcare Improvement, and used their rapid cycle change method. Particularly powerful systems change concepts were driving out fear, ""trapping"" errors and learning from them, focusing on outcome rather than on input, simplifying and standardizing, using constraints and ""forcing functions,"" reducing handoffs, and paying attention to human factors. RESULTS: Applying these concepts to our chemotherapy delivery system, we have achieved an 84% decrease in the number of chemotherapy errors that actually reach patients per 1,000 chemotherapy doses, and have sustained that improvement for 5 years. CONCLUSION: Factors contributing to our success include the rapid cycle change method, strong support from hospital administration, grassroots participation, and a tradition of interdisciplinary cooperation. Computerized direct physician order entry and cooperative group participation have had mixed effects. Continued efforts at improvement have been key to holding our gains. Although specific problems and changes may not be relevant to other organizations, the concepts and methods we used are generally applicable.",15/12/2002,13/11/2018 10:47,14/04/2020 08:35,,4705-4712,,24,20,,J Clin Oncol,,,,,,,,eng,,,,,,,PMID: 12488417,,,,Humans; Safety; Medication Errors/*prevention & control; *Patient Care Team; Multi-Institutional Systems; Neoplasms/drug therapy; Medication Errors – Prevention and Control; Multiinstitutional Systems; Multidisciplinary Care Team; Antineoplastic Agents – Administration and Dosage; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QZMHJDPL,journalArticle,2001,"Kennedy, V. C.; Moore, F. I.",A systems approach to public health workforce development.,Journal of public health management and practice : JPHMP,,1078-4659 1078-4659,,,"During the 1990s, several distinct but interrelated efforts to strengthen the public health infrastructure were launched. Defining public health work in terms of core functions and essential services, these efforts focused on the competence of the workforce and the performance of public health agencies. The systems approach offered here highlights the relationships and interdependencies among these three components of public health practice: (1) the work, (2) the worker, and (3) the work setting. The model suggests that advances in public health workforce development may require major public health organizational development efforts.",2001-07,13/11/2018 10:47,14/04/2020 08:34,,17-22,,4,7,,J Public Health Manag Pract,,,,,,,,eng,,,,,,,PMID: 11434036,,,,"Humans; United States; Efficiency, Organizational; Models, Organizational; Staff Development/*organization & administration; Competency-Based Education; Professional Competence; Public Health Administration/*manpower; Public Health Practice; Public Health/*education/manpower; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 92JX6BMB,journalArticle,2012,"Durand, Audrey; Gagne, Christian; Nshimyumukiza, Léon; Gagnon, Mathieu; Rousseau, François; Giguere, Yves; Reinharz, Daniel",Population-Based Simulation for Public Health: Generic Software Infrastructure and Its Application to Osteoporosis,"IEEE Transactions on Systems, Man, and Cybernetics - Part A: Systems and Humans",,"1083-4427, 1558-2426",10.1109/TSMCA.2012.2210210,http://ieeexplore.ieee.org/document/6330029/,"Policy-making in public health has great socio-economical consequences and must be done using the best available knowledge on the possible options. These processes are often too complex to be evaluated through analytical methods, such that computer simulations are often the best way to produce quantitative evaluations of their performances. For that purpose, we are proposing a complete software infrastructure for the simulation of public health processes. This software stack includes a generic population-based simulator called SynCHroNous Agent- and Population-based Simulator, which has a modern object-oriented software architecture, and is completely configured through eXtensible Markup Language files. These configuration files can themselves be produced by a graphical user interface that allows modeling of public health simulation by nonprogrammers. This software infrastructure has been illustrated with the real-life case study of osteoporosis prevention in adult women populations. This example, which is of great interest for Quebec health decision makers, provides insightful results for comparing several prevention strategies on a realistic population.",2012-11,15/11/2018 08:18,14/04/2020 08:34,15/11/2018 08:18,1396-1409,,6,42,,,Population-Based Simulation for Public Health,,,,,,,,,,,,Crossref,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GRIGFNAG,conferencePaper,2014,"Samah, Azurah A.; Wah, Lau Kee; Desa, Muhammad Ishak; Majid, Hairudin Abdul; Azmi, Nurulhuda Firdaus Mohd; Salleh, Nordin; Bakar, Azlina Abu; Manual, Adilius",Decision Support System Using System Dynamics Simulation Modelling for Projection of Dentist Supply,2014 International Conference on Computer Assisted System in Health,978-1-4799-8822-8,,10.1109/CASH.2014.18,http://ieeexplore.ieee.org/document/7286664/,"This paper describes the development of a decision support system (DSS) using System Dynamics (SD) simulation approach to project and analyse the supply of dentist at both local and private Malaysian healthcare provider from 2015 to 2030. The project was driven by the need to provide sustainable, quality dental services in a complex environment given fluctuations in dental graduate numbers, migrations, attritions and activities. The developed DSS using VENSIM software described in this paper is flexible and expandable. It can be used to monitor future changes in dental workforce and provide a comprehensive and structured policy analysis to policy-makers and health managers, within the Ministry of Health Malaysia.",2014-12,15/11/2018 08:18,14/04/2020 08:34,15/11/2018 08:18,22-25,,,,,,,,,,,IEEE,"Kuala Lumpur, Malaysia",,,,,,Crossref,,,"

1st International Conference on Computer Assisted System in Health (CASH), Univ Putra Malaysia, Kuala Lumpur, MALAYSIA, DEC 19-21, 2014

",,,System dynamics; 1; 210,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2014 International Conference on Computer Assisted System in Health (CASH),,,,,,,,,,,,,,, 7WERHMDC,conferencePaper,2016,"Stephens, Sonia; Applen, J. D.",Rhetorical dimensions of social network analysis visualization for public health,2016 IEEE International Professional Communication Conference (IPCC),978-1-5090-1761-4,,10.1109/IPCC.2016.7740480,http://ieeexplore.ieee.org/document/7740480/,"This presentation describes how social network analysis (SNA) can be applied and used in technical communication. We focus on using SNA diagrams for public health communication. SNA diagrams convey the dynamics of the transmission of disease and other complex networked relationships. We discuss three key connection patterns of relevance to public health applications: degree centrality, Eigenvector centrality, and betweenness centrality. This is followed by an overview of existing literature on disease transmission patterns and SNA. Using Gephi, an open-source software package, simple and clear renderings of the three centrality patterns are illustrated. We then describe how technical communicators can appropriately emphasize key features using visual rhetoric, and discuss the need to be mindful of how any graphics producing technology has its own built-in biases that may have rhetorical effects.",2016-10,15/11/2018 08:18,14/04/2020 08:35,15/11/2018 08:18,01-Apr,,,,,,,,,,,IEEE,"Austin, TX, USA",,,,,,Crossref,,,"

IEEE International Professional Communication Conference (IPCC), Austin, TX, OCT 02-05, 2016

",,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 IEEE Professional Communication Society (ProComm),,,,,,,,,,,,,,, STRJQ47Y,journalArticle,2014,"Xie, Xiaolei; Li, Jingshan; Swartz, Colleen H.; DePriest, Paul",Improving Response-Time Performance in Acute Care Delivery: A Systems Approach,IEEE Transactions on Automation Science and Engineering,,"1545-5955, 1558-3783",10.1109/TASE.2013.2258913,http://ieeexplore.ieee.org/document/6510536/,"Improving the efficacy of rapid response operations in acute care delivery to ensure patient safety and care quality is of significant importance. In this paper, we study the response time performance (RTP) in rapid response operations. Such performance is defined as the probability that an appropriate decision responding to patient deterioration can be made within a desired time period. First, we derive a closed formula to evaluate the RTP by assuming exponential response time, and investigate the system-theoretic properties. Next, we introduce a bottleneck indicator to identify the response whose improvement will lead to the largest improvement in RTP. Then, we extend the study to non-exponential response time scenario. An approximation formula is proposed to evaluate RTP. Finally, a case study at the University of Kentucky Chandler Hospital is introduced to illustrate the applicability of the method.",2014-10,15/11/2018 08:21,14/04/2020 08:35,15/11/2018 08:21,1240-1249,,4,11,,,Improving Response-Time Performance in Acute Care Delivery,,,,,,,,,,,,Crossref,,,,,,1; System Analysis; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MT7H94FZ,conferencePaper,2017,"Ostroy, Greg; Prieto, Diana; Gu, Yuwen; Dedoncker, Elise; Paul, Rajib",Flu MODELO 1.0: A simulation model and graphic interface for training and decision support for influenza management,2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM),978-1-5090-3050-7,,10.1109/BIBM.2017.8218029,http://ieeexplore.ieee.org/document/8218029/,"There are many models for simulating infectious disease outbreaks that assist health policy officials in making better decisions about mitigation strategies in the event of an epidemic. However, none of the existing models address the need to train students and policy makers in the concepts and use of such models. In this paper, we present Flu MODELO 1.0, an implementation of a model that simulates an outbreak of influenza that is mitigated with a variety of strategies. Flu MODELO 1.0 is coupled with a GUI for running, replicating, and analyzing simulations. A novel addition in the GUI is the module for educating users about the concepts used in flu outbreak simulation. Flu MODELO 1.0 includes a parallelized version for use in simulating large populations.",2017-11,15/11/2018 08:22,14/04/2020 08:35,15/11/2018 08:22,2287-2289,,,,,,Flu MODELO 1.0,,,,,IEEE,"Kansas City, MO",,,,,,Crossref,,,"

IEEE International Conference on Bioinformatics and Biomedicine (IEEE BIBM), Kansas City, MI, NOV 13-16, 2017

",,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM),,,,,,,,,,,,,,, E946KGV7,conferencePaper,2011,"Warner, Thomas R.; Bowling, Lawrence J.; Erikson, Caleb W.; Hui, Derrick S.; Marsh, Christopher J.; Teague, Edward B.; Brown, Donald E.","Agent-based modeling of public health infrastructure projects in Jalalabad, Afghanistan",2011 IEEE Systems and Information Engineering Design Symposium,978-1-4577-0446-8,,10.1109/SIEDS.2011.5876849,http://ieeexplore.ieee.org/document/5876849/,"Successful counterinsurgency and development in post-war societies require an extraordinarily complex integration of military, political, and socioeconomic operations. In order to combat insurgency and stimulate growth and stabilization in regions of Afghanistan, the International Security Assistance Force has charged the U.S. Army Corps of Engineers with developing an optimal portfolio of infrastructure projects. These projects must ultimately satisfy three lines of operation: security, governance, and development. As a proof of concept, a simulation was developed that measures the quantifiable effects of various project portfolios on citizens' health in the context of Jalalabad, Afghanistan. This tool utilizes a combination of agent-based modeling and Geographic Information Systems to measure the effect of health related infrastructure projects on a local scale. After simulating sixteen portfolios of projects, we provide a recommended set of projects for completion by the Army Corps of Engineers in Jalalabad.",2011-04,15/11/2018 08:22,14/04/2020 08:34,15/11/2018 08:22,24-28,,,,,,,,,,,IEEE,"Charlottesville, VA, USA",,,,,,Crossref,,,"

IEEE Systems and Information Engineering Design Symposium (SIEDS), Univ Virginia, Charlottesville, VA, APR 29, 2011

",,,1; Agent Based; 210,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2011 Systems and Information Engineering Design Symposium (SIEDS),,,,,,,,,,,,,,, RVNXQXE5,conferencePaper,2009,"Zhang, Yupeng; Lee, Malrey; Gatton, Thomas M.",Agent-Based Web Healthcare Systems for Real-Time Chronic Disease,2009 Congress on Services - I,978-0-7695-3708-5,,10.1109/SERVICES-I.2009.104,http://ieeexplore.ieee.org/document/5190763/,"The increasing trends in the occurrence of chronic diseases, such as diabetes and hypertension, and an aging population present serious near-term problems in providing suitable healthcare within the existing medical structure. Further, ill and elderly patients experiencing mobility and transportation issues are at risk in obtaining both regular and emergency medical treatment. Mobile health monitoring systems can provide 24/7 health-care services and address these anticipated problems. However, the large number of patients and their related data cannot be efficiently processed with current systems and an efficient processing approach is needed for real-time response requirements for critical health situations. This paper proposes an efficient real-time Knowledge Base architecture for agent-based web Health Care Center (HCC) patient monitoring system for chronic disease management. The proposed system uses Case Based Reasoning (CBR) to improve diagnostic knowledge and is implemented in a diabetes monitoring and management system. An evaluation of the system's performance is presented for evaluation and comparison to current technologies.",2009-07,15/11/2018 08:22,14/04/2020 08:34,15/11/2018 08:22,14-21,,,,,,,,,,,IEEE,"Los Angeles, CA, USA",,,,,,Crossref,,,"

4th IEEE Congress on Services, Los Angeles, CA, JUL 06-10, 2009

",,,1; agent based; 320,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2009 IEEE Congress on Services (SERVICES),,,,,,,,,,,,,,, W5BBGTFQ,journalArticle,2018,"Ferguson, Neina F.; Estis, Julie M.",Training Students to Evaluate Preterm Infant Feeding Safety Using a Video-Recorded Patient Simulation Approach.,American Journal of Speech-Language Pathology,,1058-0360,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=129481713&site=ehost-live,"Purpose: The purpose of this study was to determine if brief video-recorded patient simulation training increased student's ability to assess feeding skills in preterm infants. Method: Baccalaureate-level nursing students (N = 52) and graduate-level speech-language pathology students (N = 42) were randomized to 1 of 2 groups: didactic training (N = 51) or didactic training plus video simulation (N = 43). Outcome measures included knowledge test scores, calculated clinical judgment scores, and clinical marker documentation accuracy. Results: Student's knowledge increased as the result of training, without differences in test scores between the 2 types of training. Students who received video simulation training interpreted simulated feeding behaviors of preterm infants more accurately than students who received didactic training. Infant distress signs were also documented with higher accuracy for students who received video simulation training. After training and regardless of method, participants correctly attributed distress behaviors during bottle-feeding to increased risk for feeding difficulty. Conclusions: In the current educational environment, training opportunities with high-risk preterm infants are constrained by access to health care settings specializing in care for this population and availability of clinical supervisors with expertise in this area of practice. Patient simulators are expensive; however, video simulation offers inexpensive opportunities for students to effectively gain knowledge and skills for assessing feeding in preterm infants. With video simulation, students effectively apply principles of preterm infant feeding to cases and practice critical thinking skills before entering related clinical practicum placements.",2018,20/11/2018 14:33,14/04/2020 08:34,,566 - 573,,2,27,,,,,,,,,,,,,,,,,,,,,Infant; Students; Nursing; Education; College; Descriptive Statistics; Effect Size; Human; Infant Feeding – Evaluation; Intervention Trials; Outcomes of Education; P-Value; Patient Simulation – Utilization; Premature; Pretest-Posttest Design; Random Assignment; Randomized Controlled Trials; Speech-Language Pathology; Sucking Behavior – Evaluation – In Infancy and Childhood; Teaching Methods; Videorecording – Utilization; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FU6CUP7G,journalArticle,2018,"Health, Anna Matheson Senior Lecturer in Public; Health, Mat Walton Senior Lecturer in Public; Fellow, Rebecca Gray Senior Research; statistics, Kirstin Lindberg Principal Analyst –; Biostatistician, Mathu Shanthakumar; Candidate, Caroline Fyfe Principal Analyst/PhD; Director, Nan Wehipeihana; Epidemiology, Barry Borman Professor of",Evaluating a community-based public health intervention using a complex systems approach.,Journal of Public Health,,1741-3842,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=132102519&site=ehost-live,"Background This article outlines the methods being used to evaluate a community-based public health intervention. This evaluation approach recognizes that not only is the intervention, Healthy Families NZ, complex, but the social systems within which it is being implemented are complex. Methods To address challenges related to complexity, we discuss three developing areas within evaluation theory and apply them to an evaluation case example. The example, Healthy Families NZ, aims to strengthen the prevention system in Aotearoa/New Zealand to prevent chronic disease in 10 different geographic areas. Central to the evaluation design is the comparative case method which recognizes that emergent outcomes are the result of 'configurations of causes'. 'Thick', mixed-data, case studies are developed, with each case considered a view of a complex system. Qualitative Comparative Analysis is the analytical approach used to systematically compare the cases over time. Conclusions This article describes an approach to evaluating a community-based public health intervention that considers the social systems in which the initiative is being implemented to be complex. The evaluation case example provides a unique opportunity to operationalize and test these methods, while extending their more frequent use within other fields to the field of public health.",2018,20/11/2018 14:33,14/04/2020 08:34,,606 - 613,,3,40,,,,,,,,,,,,,,,,,,,,,Health Promotion; New Zealand; Public Health; Government Programs; 1; Human; Qualitative Studies; Chronic Disease – Prevention and Control; Community Health Services – Evaluation – New Zealand; Comparative Studies; Models; Theoretical; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MR8F45CL,journalArticle,2018,"Befus, Deanna R.; Hassmiller Lich, Kristen; Kneipp, Shawn M.; Bettger, Janet P.; Coeytaux, Remy R.; Humphreys, Janice C.","A Qualitative, Systems Thinking Approach to Study Self-Management in Women With Migraine.",Nursing Research,,0029-6562,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=131766539&site=ehost-live,"Supplemental digital content is available in the text. Background: A dearth of effective and affordable treatment options has rendered nonpharmacological self-management a crucial part of living with migraine—a debilitating neurobiological condition without cure that disproportionately disables vulnerable women. Objective: The aim of the study was to describe the development and use of a systems thinking, problem-structuring data collection approach that was applied to the study of migraine self-management with women in diverse social locations. Methods: Two systems mapping activities were developed for use in focus groups: one to unpack a migraine episode (system support map) and the other (connection circle [CC]) to construct a mental model of self-management. Later in the process, a strengths-based problem-solving tool was developed to replace the CC. Results: The CCs—often enlightening for affluent participants—left marginalized women feeling overwhelmed and defeated, as a solution to one challenge became the cause of another. Through constant comparison analysis, we recalibrated the approach using a theory, clinical experience, and participant feedback and replaced the CC with a strengths-based problem-solving activity highlighting relationships and trade-offs in a more agential, actionable way. Discussion: Bringing a critical lens and strengths-based approaches to work with vulnerable populations can replace traditional deficit thinking in healthcare, developing options for leveraging resources and understanding complex health behaviors without losing sight of systemic, distributional justice issues. These systems thinking tools can provide a way to extrapolate the complexities of actual self-management behaviors and challenges faced by vulnerable women with migraine versus what they may be instructed to do by a medical model that does not always account for the social and structural determinants of equity and health.",2018,20/11/2018 14:33,14/04/2020 08:34,,395 - 403,,5,67,,,,,,,,,,,,,,,,,,,,,Socioeconomic Factors; Female; Focus Groups; North Carolina; Problem Solving; Human; Descriptive Research; Qualitative Studies; Constant Comparative Method; Content Analysis; Convenience Sample; Maps; Migraine – Therapy; Protocols; Self Care; Thinking; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VQKWVMVJ,journalArticle,2018,"Leslie, Hannah H.; Hirschhorn, Lisa R.; Marchant, Tanya; Doubova, Svetlana V.; Gureje, Oye; Kruk, Margaret E.",Health systems thinking: A new generation of research to improve healthcare quality.,PLoS Medicine,,1549-1277,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=132697836&site=ehost-live,"Hannah Leslie and colleagues of the High-Quality Health Commission discuss in an Editorial the findings from their report that detail the improvements needed to prevent declines in individuals' health as the scope and quality of health systems increase. Patient-centered care at the population level, improved utility of research products, and innovative reporting tools to help guide the development of new methods are key to improved global healthcare.",2018,20/11/2018 14:33,14/04/2020 08:34,,01-Apr,,10,15,,,,,,,,,,,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QL5W44QG,journalArticle,2018,"Bordley, James; Sakata, Knewton K.; Bierman, Jesse; McGrath, Karess; Mulanax, Ashley; Nguyen, Linh; Mohan, Vishnu; Gold, Jeffrey A.","Use of a Novel, Electronic Health Record-Centered, Interprofessional ICU Rounding Simulation to Understand Latent Safety Issues.",Critical Care Medicine,,0090-3493,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=131737037&site=ehost-live,"Objectives: The electronic health record is a primary source of information for all professional groups participating in ICU rounds. We previously demonstrated that, individually, all professional groups involved in rounds have significant blind spots in recognition of patient safety issues in the electronic health record. However, it is unclear how team dynamics impacts identification and verbalization of viewed data. Therefore, we created an ICU rounding simulation to assess how the interprofessional team recognized and reported data and its impact on decision-making.Design: Each member of the ICU team reviewed a simulated ICU chart in the electronic health record which contained embedded patient safety issues. The team conducted simulated rounds according to the ICU's existing rounding script and was assessed for recognition of safety issues.Setting: Academic medical center.Subjects: ICU residents, nurses, and pharmacists.Intervention: None.Measurements and Main Results: Twenty-eight teams recognized 68.6% of safety issues with only 50% teams having the primary diagnosis in their differential. Individually, interns, nurses, and pharmacists recognized 30.4%, 15.6%, and 19.6% of safety items, respectively. However, there was a negative correlation between the intern's performance and the nurse's or the pharmacist's performance within a given team. The wide variance in recognition of data resulted in wide variance in orders. Overall, there were 21.8 orders requested and 21.6 orders placed per case resulting in 3.6 order entry inconsistencies/case. Between the two cases, there were 145 distinct orders place with 43% being unique to a specific team and only 2% placed by all teams.Conclusions: Although significant blind spots exist in the interprofessional team's ability to recognize safety issues in the electronic health record, the inclusion of other professional groups does serve as a partial safety net to improve recognition. Electronic health record-based, ICU rounding simulations can serve as a test-bed for innovations in ICU rounding structure and data collection.",2018,20/11/2018 14:33,14/04/2020 08:34,,1570 - 1576,,10,46,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2JI9RH7T,journalArticle,2018,"Whalen, Madeleine; Hansoti, Bhakti; Hsieh, Yu-Hsiang; Saheed, Mustapha; Signer, Dani; Rothman, Richard",Translation of Public Health Theory into Nursing Practice: Optimization of a Nurse-Driven HIV Testing Program in the Emergency Department.,JEN: Journal of Emergency Nursing,,0099-1767,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=131805623&site=ehost-live,"Image 1 Contribution to Emergency Nursing Practice • Describes the emergency nurse’s role in public health screening initiatives. • Quantifies specific strategies to optimize HIV testing in the emergency department, including the key role of nursing. • Provides description of Centers for Disease Control and Prevention HIV testing guidelines and their translation into practice.",2018,20/11/2018 14:33,14/04/2020 08:35,,446 - 452,,5,44,,,,,,,,,,,,,,,,,,,,,United States; Electronic Health Records; Workflow; Human; Emergency Service; Cost Benefit Analysis; Emergency Nursing; Health Screening; HIV Infections – Diagnosis; Nursing Role; Program Implementation; Retrospective Design; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WCIL8FQG,journalArticle,2018,"Nianogo, Roch A.; Arah, Onyebuchi A.",Impact of Public Health Interventions on Obesity and Type 2 Diabetes Prevention: A Simulation Study.,American Journal of Preventive Medicine,,0749-3797,doi: 10.1016/j.amepre.2018.07.014.,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=132970165&site=ehost-live,"Introduction: Little is known about what interventions worked or did not work in slowing the obesity epidemic. The long-term comparative effectiveness of environmental and behavioral public health interventions for obesity and type 2 diabetes prevention over an individual's life course is relatively unexplored. The potential impact and long-term collective effectiveness of environmental and behavioral interventions on obesity and type 2 diabetes throughout the life course was evaluated.Methods: The Virtual Los Angeles Obesity Model developed in 2016 was used to estimate the incidence and prevalence of obesity and type 2 diabetes under current and hypothetical interventions among 98,000 individuals born in 2009 and followed from birth to age 65 years. Analyses were performed in 2016 and completed in 2018.Results: The 48-year risk of type 2 diabetes was 0.533 (95% CI=0.446, 0.629) under the natural course, 0.451 (95% CI=0.334, 0.570) under the physical activity intervention, and 0.443 (95% CI=0.389, 0.495) under the fast-food intervention. The 64-year risk of obesity was 0.892 (95% CI=0.879, 0.903) under the natural course, 0.876 (95% CI=0.850, 0.899) under the physical activity intervention, and 0.864 (95% CI=0.856, 0.873) under the fast-food intervention. The other interventions had little or no long-term effects. When all the interventions were applied, the population risk ratios were 0.942 (95% CI=0.914, 0.967) and 0.634 (95% CI=0.484, 0.845) for obesity and type 2 diabetes, respectively.Conclusions: Implementing health interventions continuously throughout the life span and in combination with other interventions could substantially halt the obesity and the type 2 diabetes epidemics.",2018,20/11/2018 14:33,14/04/2020 08:34,,795 - 802,,6,55,,,,,,,,,,,,,,,,,,,,,1; Prevention; Agent Based; stochastic dynamic discrete-time ABM; 210,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, N2HJSYT7,journalArticle,2017,"ALLISON, GAIL",Violence Prevention Exercises: Enhancing safety through simulation training.,Canadian Nurse,,0008-4581,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=125212465&site=ehost-live,"The article focuses on Violence Prevention Exercises (VPE), a scenario-based simulation training program in line with the violence prevention education at Vancouver Coastal Health (VCH) in British Columbia. Topics covered include the limitations of the Provincial Violence Prevention Curriculum (PVPC) which was implemented in health authorities in 2012, process of developing VPE and implementation of VPE and lessons learned from the pilot.",2017,20/11/2018 14:33,14/04/2020 08:34,,36 - 38,,5,113,,,,,,,,,,,,,,,,,,,,,Program Development; Outcomes of Education; Program Implementation; British Columbia; Health Personnel – Education – British Columbia; Occupational Safety; Simulations; Workplace Violence – Education – British Columbia; Workplace Violence – Prevention and Control – British Columbia; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QRBALWD9,journalArticle,2018,"Joglekar, Sagar; Sastry, Nishanth; Coulson, Neil S.; Taylor, Stephanie JC; Patel, Anita; Duschinsky, Robbie; Anand, Amrutha; Evans, Matt Jameson; Griffiths, Chris J.; Sheikh, Aziz; Panzarasa, Pietro; De Simoni, Anna; Jameson Evans, Matt",How Online Communities of People With Long-Term Conditions Function and Evolve: Network Analysis of the Structure and Dynamics of the Asthma UK and British Lung Foundation Online Communities.,Journal of Medical Internet Research,,1438-8871,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=131093133&site=ehost-live,"Background: Self-management support can improve health and reduce health care utilization by people with long-term conditions. Online communities for people with long-term conditions have the potential to influence health, usage of health care resources, and facilitate illness self-management. Only recently, however, has evidence been reported on how such communities function and evolve, and how they support self-management of long-term conditions in practice.Objective: The aim of this study is to gain a better understanding of the mechanisms underlying online self-management support systems by analyzing the structure and dynamics of the networks connecting users who write posts over time.Methods: We conducted a longitudinal network analysis of anonymized data from 2 patients' online communities from the United Kingdom: the Asthma UK and the British Lung Foundation (BLF) communities in 2006-2016 and 2012-2016, respectively.Results: The number of users and activity grew steadily over time, reaching 3345 users and 32,780 posts in the Asthma UK community, and 19,837 users and 875,151 posts in the BLF community. People who wrote posts in the Asthma UK forum tended to write at an interval of 1-20 days and six months, while those in the BLF community wrote at an interval of two days. In both communities, most pairs of users could reach one another either directly or indirectly through other users. Those who wrote a disproportionally large number of posts (the superusers) represented 1% of the overall population of both Asthma UK and BLF communities and accounted for 32% and 49% of the posts, respectively. Sensitivity analysis showed that the removal of superusers would cause the communities to collapse. Thus, interactions were held together by very few superusers, who posted frequently and regularly, 65% of them at least every 1.7 days in the BLF community and 70% every 3.1 days in the Asthma UK community. Their posting activity indirectly facilitated tie formation between other users. Superusers were a constantly available resource, with a mean of 80 and 20 superusers active at any one time in the BLF and Asthma UK communities, respectively. Over time, the more active users became, the more likely they were to reply to other users' posts rather than to write new ones, shifting from a help-seeking to a help-giving role. This might suggest that superusers were more likely to provide than to seek advice.Conclusions: In this study, we uncover key structural properties related to the way users interact and sustain online health communities. Superusers' engagement plays a fundamental sustaining role and deserves research attention. Further studies are needed to explore network determinants of the effectiveness of online engagement concerning health-related outcomes. In resource-constrained health care systems, scaling up online communities may offer a potentially accessible, wide-reaching and cost-effective intervention facilitating greater levels of self-management.",2018,20/11/2018 14:33,14/04/2020 08:34,,298 - 314,,7,20,,,,,,,,,,,,,,,,,,,,,asthma; 00; network analysis; chronic obstructive pulmonary disease; COPD; digital health social network; online community; online forums; self-management; superusers; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NWQVK88Q,journalArticle,2018,"Rotstein, Anat; Roe, David; Gelkopf, Marc; Shadmi, Efrat; Levine, Stephen Z.",Quality of life disparities between persons with schizophrenia and their professional caregivers: Network analysis in a National Cohort.,Schizophrenia Research,,0920-9964,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=130302144&site=ehost-live,"Background: Disparities between mental health patients and their professional caregivers in quality of life appraisals have been identified, however, the structure that such disparities assume is unknown.Aims: To examine the network structure of quality of life appraisals and disparities using network analysis.Methods: Participants were 1639 persons with schizophrenia using psychiatric rehabilitation services and their primary professional caregivers (N=582). Quality of life for persons with schizophrenia was measured based on an abbreviated version of the Manchester Short Assessment of Quality of Life. Appraisals were made self-reported and by professional caregivers. Disparities scores between the aforementioned were computed. Network analysis was performed on all quality of life appraisals. Sensitivity analyses were conducted.Results: The self-appraised network significantly (p<0.05) differed by network strength compared to the caregiver-appraised network. Self-appraised network communities (clusters of quality of life items) were health conditions and socioeconomic system, whereas caregiver-appraised network communities were social activities, and combined socioeconomic and health conditions. Strength centrality was highest for self-appraised social status and for caregiver-appraised residential status (Z=1.63, Z=1.12, respectively). The disparity scores network clustered into two communities: social relations and combined financial and health conditions. The most central appraisal disparities were in social status.Conclusions: Quality of life differed when self-appraised by persons with schizophrenia compared to when appraised by their professional caregivers, yet the salient role of social relations was shared. The latter may be an initial focus of discussion by persons with schizophrenia and their caregivers.",2018,20/11/2018 14:33,14/04/2020 08:35,,109 - 115,,,197,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, H722HFAC,journalArticle,2017,"Struessel, Tamara S.; Rodriguez, Jennifer W.; Van Zytveld, Chelsea R.",Advocating for a Systems Approach to Enhance Patient Safety in Physical Therapy Practice: A Clinical Commentary.,HPA Resource,,1931-6313,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=120699018&site=ehost-live,"The purpose of this commentary is to bring attention to patient safety in physical therapy, especially to the system factors that contribute to error, and to advocate for improving methods of reducing patient harm by increasing focus on a systems approach. Healthcare delivery is a complex undertaking with multiple individuals working to provide the best care in technically challenging environments. This, combined with human fallibility, makes error inevitable. However, error does not have to result in patient harm. Historically, patient safety efforts in physical therapy have focused on the individual provider. Research shows that most patient harm occurs because of a recurrent set of circumstances and system conditions rather than solely the error of one provider.",2017,20/11/2018 14:33,14/04/2020 08:35,,J22 - J31,,1,17,,,,,,,,,,,,,,,,,,,,,Patient Safety; Quality Improvement; Professional Competence; Health Care Delivery; Physical Therapy Practice; Treatment Errors – Prevention and Control; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, D8NJA5VI,journalArticle,2018,"Davis, Diane; Koppelman, Dara; Gordon, Jessica; Coleman, Susan V.; Heitzler, Ella T.; Fall-Dickson, Jane M.",Effect of an Academic–Community Partnership Simulation Education Program on Quality and Safety Education for Nurses Competency Domains for Bachelor of Science in Nursing Students.,Clinical Simulation in Nursing,,1876-1399,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=129152682&site=ehost-live,"Background Despite the shift to community-based health care, baccalaureate nursing students may have little opportunity to develop competencies for future practice in community settings. Method This mixed methods study explored effects of an academic–community Simulation Education Program on the Quality and Safety Education for Nurses domains of teamwork, collaboration, and patient-centered care through a pre–post design, the Interprofessional Attitudes Scale, and focus groups. Results Participants (N = 32) were bachelor of science in nursing (n = 11) and medical assistant students (n = 21). Both groups had significantly increased postsimulation Interprofessional Attitudes Scale total scores (N = 32; p = .032) and teamwork, roles and responsibilities ( p = .003), patient-centeredness ( p = .043), and diversity and ethics ( p = .025) subscales' scores. Five themes emerged from focus groups: gaining different perspectives, learning about one's own and other's roles, having confidence in communication, having empathy for patients, and realism of the simulation experience. Conclusions Results suggest that simulation with role-play is a best practice to promote competencies in teamwork, collaboration, and patient-centered care.",2018,20/11/2018 14:33,14/04/2020 08:34,,56 - 63,,,18,,,,,,,,,,,,,,,,,,,,,Clinical Competence; Focus Groups; Teamwork; Collaboration; Nursing; Education; Role Playing; Human; Pretest-Posttest Design; Baccalaureate; Scales; Simulations; Multimethod Studies; Patient Centered Care; Student Attitudes; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9PP9NX2C,journalArticle,2018,"McDonald, Shelley R.; Heflin, Mitchell T.; Whitson, Heather E.; Dalton, Thomas O.; Lidsky, Michael E.; Liu, Phillip; Poer, Cornelia M.; Sloane, Richard; Thacker, Julie K.; White, Heidi K.; Yanamadala, Mamata; Lagoo-Deenadayalan, Sandhya A.",Association of Integrated Care Coordination With Postsurgical Outcomes in High-Risk Older Adults: The Perioperative Optimization of Senior Health (POSH) Initiative.,JAMA Surgery,,2168-6254,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=129693542&site=ehost-live,"Importance: Older adults undergoing elective surgery experience higher rates of preventable postoperative complications than younger patients.Objective: To assess clinical outcomes for older adults undergoing elective abdominal surgery via a collaborative intervention by surgery, geriatrics, and anesthesia focused on perioperative health optimization.Design, Setting, and Participants: Perioperative Optimization of Senior Health (POSH) is a quality improvement initiative with prospective data collection. Participants in an existing geriatrics-based clinic within a single-site academic health center were included if they were at high risk for complications (ie, older than 85 years or older than 65 years with cognitive impairment, recent weight loss, multimorbidity, or polypharmacy) undergoing elective abdominal surgery. Outcomes were compared with a control group of patients older than 65 years who underwent similar surgeries by the same group of general surgeons immediately before implementation of POSH.Main Outcomes and Measures: Primary outcomes included length of stay, 7- and 30-day readmissions, and level of care at discharge. Secondary outcomes were delirium and other major postoperative complications. Outcomes data were derived from institutional databases linked with electronic health records and billing data sets.Results: One hundred eighty-three POSH patients were compared with 143 patients in the control group. On average, patients in the POSH group were older compared with those in the control group (75.6 vs 71.9 years; P < .001; 95% CI, 2.27 to 5.19) and had more chronic conditions (10.6 vs 8.5; P = .001; 95% CI, 0.86 to 3.35). Median length of stay was shorter among POSH patients (4 days vs 6 days; P < .001; 95% CI, -1.06 to -4.21). Patients in the POSH group had lower readmission rates at 7 days (5 of 180 [2.8%] vs 14 of 142 [9.9%]; P = .007; 95% CI, 0.09 to 0.74) and 30 days (14 of 180 [7.8%] vs 26 of 142 [18.3%]; P = .004; 95% CI, 0.19 to 0.75) and were more likely to be discharged home with self-care (114 of 183 [62.3%] vs 73 of 143 [51.1%]; P = .04; 95% CI, 1.02 to 2.47). Patients in the POSH group experienced fewer mean number of complications (0.9 vs 1.4; P < .001; 95% CI, -0.13 to -0.89) despite higher rates of documented delirium (52 of 183 [28.4%] vs 8 of 143 [5.6%]; P < .001; 95% CI, 3.06 to 14.65). A greater proportion of POSH patients underwent laparoscopic procedures (92 of 183 [50%] vs 55 of 143 [38.5%]; P = .001; 95% CI, 1.04 to 2.52). Tests for interactions between POSH patients and procedure type were insignificant for all outcomes.Conclusions and Relevance: Despite higher mean age and morbidity burden, older adults who participated in an interdisciplinary perioperative care intervention had fewer complications, shorter hospitalizations, more frequent discharge to home, and fewer readmissions than a comparison group.",2018,20/11/2018 14:33,14/04/2020 08:34,,454 - 462,,5,153,,,,,,,,,,,,,,,,,,,,,1; Group Comparison; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6FWN6PWM,journalArticle,2018,"Allott, Mindy L.; Sofra, Tanya; O'Donnell, Gail; Hearne, Jeremy L.; Naccarella, Lucio",Building health literacy responsiveness in Melbourne's west: a systems approach.,Australian Health Review,,0156-5788,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=127755495&site=ehost-live,"With high health inequities among some population groups, health professionals and organisations are increasingly taking action on health literacy. This case study demonstrates how a systems approach to health literacy responsiveness created change across a region. From 2013 to 2017 the Health Literacy Development Project incorporating a training course and community of practice (the Project) targeted the health and community services system in Melbourne's west. The Project created a ripple effect that built health literacy responsiveness at the individual and organisational level. This contributed to increased use of health literacy practices and led to systems change across the region. Creating change within the health and community services system is extremely challenging. This case study provides some evidence that a systems approach can support change in the health literacy responsiveness of a regional health and community services system over a 4-year timeframe.",2018,20/11/2018 14:33,14/04/2020 08:34,,31 - 35,,1,42,,,,,,,,,,,,,,,,,,,,,Socioeconomic Factors; Focus Groups; Victoria; Human; Curriculum Development; Vignettes; Course Evaluation; Funding Source; Health Literacy – Victoria; Interviews; Organizational Change; Outcome Assessment; Pilot Studies; Seminars and Workshops; Survey Research; Systems Design; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HYCZNIFR,journalArticle,2018,"Boothby, Johanna; Little, Elaine",Introducing Nursing Students to an Environmental Safety Assessment Through Simulation.,Teaching & Learning in Nursing,,1557-3087,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=130262435&site=ehost-live,"In response to the Institute of Medicine report criticizing health care professionals' competence in providing safe patient care, health care educators were challenged to transform their nursing programs. One powerful tool in developing competent nurses, without endangering patients, is simulation. This article discusses advantages and disadvantages of using simulation as a teaching strategy and describes how to teach environmental safety concepts to beginning nursing students, through a simulated patient room using an environmental safety assessment.",2018,20/11/2018 14:33,14/04/2020 08:34,,190 - 192,,3,13,,,,,,,,,,,,,,,,,,,,,Clinical Competence; Nursing; Education; Outcomes of Education; Simulations; Professional Development; Teaching Methods – Evaluation; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ES6WXR92,journalArticle,2017,"Higham, H.; Baxendale, B.",To err is human: use of simulation to enhance training and patient safety in anaesthesia.,BJA: The British Journal of Anaesthesia,,0007-0912,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=126612303&site=ehost-live,"Human beings who work in complex, dynamic, and stressful situations make mistakes. This is as true for anaesthetists as for any other health-care professional, but we face unique challenges in the many roles and responsibilities we have in diverse clinical contexts. As a profession, we are well versed in the development and utilization of improvement techniques and technologies that prioritize high-quality, safe care for patients. This article focuses on one particular domain of patient safety in which anaesthetists have been pre-eminent, the use of simulation in training to improve both professional capabilities and patient safety in anaesthetic practice. This review considers the impact of error in health care; the role of anaesthetists in promoting simulation-based education for the development of clinical skills and improved teamwork; and their role in disseminating human factors and quality improvement science to enhance safety in the clinical workplace. Finally, we consider our position at the vanguard of developments in patient safety and how the profession should continue to pursue a leadership role in the application of simulation-based interventions to training and systems design across health care.",2017,20/11/2018 14:33,14/04/2020 08:34,,i106 - i114,,,119,,,,,,,,,,,,,,,,,,,,,safety; education; 00; anaesthesia; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, M59Q26TL,journalArticle,2018,"Griffiths, Barbara",Preparing Tomorrow's Nurses for Collaborative Quality Care Through Simulation.,Teaching & Learning in Nursing,,1557-3087,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=126993356&site=ehost-live,"Simulations were introduced into a 2nd semester associate degree nursing program as a teaching strategy designed to enhance learning, promote critical thinking, and bridge the gap between theory and practice. Minimizing error, promoting quality care, and establishing teamwork were among the main objectives. Decision making and completion of assignments and activities were shared. Simulation helps nursing students to build communication skills and collaborate characteristics essential to working within the interprofessional team in today's health care climate.",2018,20/11/2018 14:33,14/04/2020 08:34,,46 - 50,,1,13,,,,,,,,,,,,,,,,,,,,,Health Promotion; Quality of Health Care; Learning; Interprofessional Relations; Decision Making; Teamwork; Students; Nursing; Education; Teaching Methods; Simulations; Professional Development; Shared; Associate; Communication Skills Training; Critical Thinking; Joint Practice; Student Assignments; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DTQ7BUD8,journalArticle,2018,"Calancie, Larissa; Anderson, Seri; Branscomb, Jane; Apostolico, Alexsandra A.; Lich, Kristen Hassmiller",Using Behavior Over Time Graphs to Spur Systems Thinking Among Public Health Practitioners.,Preventing Chronic Disease,,1545-1151,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=127769025&site=ehost-live,"Public health practitioners can use Behavior Over Time (BOT) graphs to spur discussion and systems thinking around complex challenges. Multiple large systems, such as health care, the economy, and education, affect chronic disease rates in the United States. System thinking tools can build public health practitioners' capacity to understand these systems and collaborate within and across sectors to improve population health. BOT graphs show a variable, or variables (y axis) over time (x axis). Although analyzing trends is not new to public health, drawing BOT graphs, annotating the events and systemic forces that are likely to influence the depicted trends, and then discussing the graphs in a diverse group provides an opportunity for public health practitioners to hear each other's perspectives and creates a more holistic understanding of the key factors that contribute to a trend. We describe how BOT graphs are used in public health, how they can be used to generate group discussion, and how this process can advance systems-level thinking. Then we describe how BOT graphs were used with groups of maternal and child health (MCH) practitioners and partners (N = 101) during a training session to advance their thinking about MCH challenges. Eighty-six percent of the 84 participants who completed an evaluation agreed or strongly agreed that they would use this BOT graph process to engage stakeholders in their home states and jurisdictions. The BOT graph process we describe can be applied to a variety of public health issues and used by practitioners, stakeholders, and researchers.",2018,20/11/2018 14:33,14/04/2020 08:34,,01-Aug,,,15,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, M24BB86C,journalArticle,2017,"Grant, Robert L.; Hood, Rick","Complex systems, explanation and policy: implications of the crisis of replication for public health research.",Critical Public Health,,0958-1596,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=125035387&site=ehost-live,"Much public health research considers interventions that influence and are influenced by both individuals’ health and the society around them; this can be described as a complex system. We consider the role of explanation alongside statistical inference as crucial to obtaining credible and useful insights, particularly in light of concerns about a ‘crisis of replication’, and reflect on the difficulty in researching complex systems. In this paper, we make a connection with Lipton’s philosophy of inference to the best explanation, and offer some tentative practical recommendations, extending suggestions from different fields. An extended hypothetical example is given on introducing ‘sugar tax’ in England.",2017,20/11/2018 14:33,14/04/2020 08:34,,525 - 532,,5,27,,,,,,,,,,,,,,,,,,,,,Health Policy; Research; Public Health; Policy Making; England; Public Policy; Carbonated Beverages; Dietary Sucrose – Legislation and Jurisprudence – England; Philosophy; Taxes – England; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GD3PJYER,journalArticle,2017,"Liebrecht, Christina M.; Lieb, Megan C.",Incorporating Quality and Safety Values into a CLABSI Simulation Experience.,Nursing Forum,,0029-6473,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=122941436&site=ehost-live,"The article presents a simulation scenario as an innovative teaching-learning strategy to assist students in identifying and preventing risks linked with central line associated bloodstream infection (CLABSI). Topics covered include the percentage of mortality resulting from healthcare-associated infection (HAI), the incorporation of quality and safety values into simulation and the components of experiential learning theory.",2017,20/11/2018 14:33,14/04/2020 08:34,,118 - 123,,2,52,,,,,,,,,,,,,,,,,,,,,Quality of Health Care; Female; Patient Safety; Aged; Inpatients; Nursing; Education; Simulations; Patient Centered Care; Catheter-Related Bloodstream Infections – Education; Catheter-Related Bloodstream Infections – Prevention and Control; Central Venous Catheters; Kolb's Experiential Learning Theory; Medical Orders; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CNKTI5AM,journalArticle,2017,"Levett-Jones, Tracy; Guinea, Stephen",The Evolution of a Mnemonic for Quality Simulation Practices.,Clinical Simulation in Nursing,,1876-1399,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=125357773&site=ehost-live,"As health care simulation continues to mature, the literature has shifted from descriptive narratives about “doing” simulation towards a greater focus on the scholarship of simulation practice. In essence, there has been a shift from viewing simulation as a technology to a pedagogy. At the same time, there has been increasing attention to what defines excellence, quality, and sustainability of simulation practice. This article presents a comprehensive overview of educational principles and practices for simulation derived from contemporary health care and education literature, framed using the mnemonic simulation. This article complements existing work into quality indicators and standards and will be relevant to a range of health care disciplines.",2017,20/11/2018 14:33,14/04/2020 08:34,,552 - 561,,11,13,,,,,,,,,,,,,,,,,,,,,Quality Improvement; Education; Health Care Delivery; Clinical Indicators; Medical; Memory; Simulations – Standards; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FTYKEJN7,journalArticle,2015,"Joubert, A.; Mulder, M.; Nel, P.",STUDENT NURSES' EXPECTATIONS OF SERVICE QUALITY VERSUS ACTUAL EXPERIENCES OF A SIMULATION AT A HIGHER EDUCATION INSTITUTION.,Africa Journal of Nursing & Midwifery,,1682-5055,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=116021472&site=ehost-live,"Simulations may assist students to deal with differences in focus between what they learn in the classroom with what is expected in the clinical practice situation - more specifically the needs of the patient. In addition, simulations assist students to become active participants in their own learning and use their knowledge when thinking and applying what they have learned in a healthcare setting. The aim of the study was to determine the relationship between nursing students' expectations regarding the quality of simulated training and their actual evaluation of the experience of such simulations. Using convenience sampling, a total of 30 student nurses completed two questionnaires that measured their expectations regarding service quality (SERVQUAL) and their actual satisfaction with the simulation. Both questionnaires had acceptable levels of reliability, except for the responsiveness and assurance dimensions of the SERVQUAL instrument. Student nurses reported high expectations related to the following aspects of service: assurance, reliability and tangibles. In addition, the majority of these expectations, except for assurance, had substantial correlations (r>0.4) with numerous dimensions associated with the actual experience of simulated training. In essence, 27 (90%) student nurses reported that they were very satisfied that the simulated training had met their expectations, and that the School of Nursing had the necessary capacity to host such simulations. Moreover, 27 (90%) students also viewed the simulations as being helpful to stimulate critical thinking. Finally, 24 students (79%) were of the opinion that simulations helped them to effectively communicate as a team.",2015,20/11/2018 14:33,14/04/2020 08:34,,75 - 88,,2,17,,,,,,,,,,,,,,,,,,,,,Female; Male; Young Adult; Students; Patient Simulation; Nursing; Education; Descriptive Statistics; Human; Outcomes of Education; Convenience Sample; Clinical; Questionnaires; Student Attitudes; Critical Thinking; Surveys; Adolescence; Cross Sectional Studies; Learning Environment; Student Experiences; Student Satisfaction; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LWGRZRCG,book,2016,"Zimmerman, Dawn M.",Impacts & Innovations. Medication Safety: Simulation Education for New RNs Promises an Excellent Return on Investment.,,,,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=112911523&site=ehost-live,"The author reviews four factors that have converged to make the need for simulated instruction one of nursing administration's top priorities, namely high costs of drug errors in the hospital inpatient setting, the preparation-practice gap, nurse perceptions, and curriculum design. Topics discussed include the tangible and intangible costs of medication errors, the gap between preparation and practice, and the challenge of integrating simulation in the education of health care practitioners.",2016,20/11/2018 14:33,14/04/2020 08:35,,,,,,,,,,,,,"Jannetti Publications, Inc.",,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JPNCGTR6,journalArticle,2017,"MONTGOMERY, CARMEL",A home care palliative sedation simulation program.,Canadian Nurse,,0008-4581,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=121857472&site=ehost-live,"The article discusses a home care palliative sedation simulation program developed with the help of the Edmonton Zone of Alberta Health Services (AHS). Topics covered include the Edmonton Zone home care program, the important role of clinical nurse specialists (CNSs) in the AHS' palliative sedation simulation program, and the implementation of the simulations sessions under the program. It also discusses the session results, and plans for the palliative sedation simulation program.",2017,20/11/2018 14:34,14/04/2020 08:34,,40 - 41,,2,113,,,,,,,,,,,,,,,,,,,,,Simulations; Hospice Care; Clinical Nurse Specialists; Hospice and Palliative Nursing; Pain Management; Sedation; Terminal Care – Education; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 23WXJ7CN,journalArticle,2017,"Mariani, Bette; Ross, Jennifer Gunberg; Paparella, Susan; Allen, Lois Ryan",Medication Safety Simulation to Assess Student Knowledge and Competence.,Clinical Simulation in Nursing,,1876-1399,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=122646400&site=ehost-live,"Background Medication administration is an important part of the nurse's role. Students and new nursing graduates often lack knowledge and competency to safely administer medications. Simulation can facilitate student learning about medication safety. Purpose This simulation intervention study tested the differences in knowledge, competency, and perceptions of medication safety between students who did and did not participate in safety enhanced medication administration simulations. Method This was a two-group pretest-posttest design. Participants completed the Medication Safety Knowledge Assessment (MSKA) and the Healthcare Professionals Patient Safety Assessment (HPPSA) pretests at the start of the semester. The control group participated in the usual simulations/debriefings; the intervention group participated in one additional medication administration simulation, as well as medication safety enhanced simulations. During the final simulation of the semester, participants’ competency in medication administration safety was rated using the Medication Safety Critical Element Checklist (MSCEC). All participants completed the MSKA and HPPSA posttests. Results Data for the MSKA were analyzed using a Knowledge Pass/Fail cut score of 21 correct answers or more to pass. The HPPSA scores were analyzed using t tests and MSCEC between groups scores were compared. There were statistically significant differences in student knowledge (MSKA) and competency (MSCEC) for students who participated in the medication safety enhanced simulations. Conclusions/Implications Medication safety is essential to ensuring patient safety; it is important to ensure that nursing graduates are well-prepared to provide safe care. Outcomes of this study support the evidence that simulation is an effective strategy to improve student learning.",2017,20/11/2018 14:34,14/04/2020 08:34,,210 - 216,,5,13,,,,,,,,,,,,,,,,,,,,,Patient Safety; Students; Patient Simulation; Descriptive Statistics; Human; Pretest-Posttest Design; Checklists; Clinical Competence – Evaluation; Drug Administration; Nursing – Psychosocial Factors; Nursing Knowledge – Evaluation; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ZMADJI2M,journalArticle,2018,"Vail, Brennan; Morgan, Melissa C.; Spindler, Hilary; Christmas, Amelia; Cohen, Susanna R.; Walker, Dilys M.","The power of practice: simulation training improving the quality of neonatal resuscitation skills in Bihar, India.",BMC Pediatrics,,1471-2431,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=131555523&site=ehost-live,"Background: Globally, neonatal mortality accounts for nearly half of under-five mortality, and intrapartum related events are a leading cause. Despite the rise in neonatal resuscitation (NR) training programs in low- and middle-income countries, their impact on the quality of NR skills amongst providers with limited formal medical education, particularly those working in rural primary health centers (PHCs), remains incompletely understood.Methods: This study evaluates the impact of PRONTO International simulation training on the quality of NR skills in simulated resuscitations and live deliveries in rural PHCs throughout Bihar, India. Further, it explores barriers to performance of key NR skills. PRONTO training was conducted within CARE India's AMANAT intervention, a maternal and child health quality improvement project. Performance in simulations was evaluated using video-recorded assessment simulations at weeks 4 and 8 of training. Performance in live deliveries was evaluated in real time using a mobile-phone application. Barriers were explored through semi-structured interviews with simulation facilitators.Results: In total, 1342 nurses participated in PRONTO training and 226 NR assessment simulations were matched by PHC and evaluated. From week 4 to 8 of training, proper neck extension, positive pressure ventilation (PPV) with chest rise, and assessment of heart rate increased by 14%, 19%, and 12% respectively (all p ≤ 0.01). No difference was noted in stimulation, suction, proper PPV rate, or time to completion of key steps. In 252 live deliveries, identification of non-vigorous neonates, use of suction, and use of PPV increased by 21%, 25%, and 23% respectively (all p < 0.01) between weeks 1-3 and 4-8. Eighteen interviews revealed individual, logistical, and cultural barriers to key NR skills.Conclusion: PRONTO simulation training had a positive impact on the quality of key skills in simulated and live resuscitations throughout Bihar. Nevertheless, there is need for ongoing improvement that will likely require both further clinical training and addressing barriers that go beyond the scope of such training. In settings where clinical outcome data is unreliable, data triangulation, the process of synthesizing multiple data sources to generate a better-informed evaluation, offers a powerful tool for guiding this process.",2018,20/11/2018 14:34,14/04/2020 08:35,,N.PAG - N.PAG,,1,18,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5Y4RYMXX,journalArticle,2016,"Stone, Kimberly P.; Patterson, Mary D.; Reid, Jennifer R.; Geis, Gary L.; Auerbach, Marc",Simulation to Improve Patient Safety in Pediatric Emergency Medicine.,Clinical Pediatric Emergency Medicine,,1522-8401,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=118025067&site=ehost-live,"Patient safety is the foundation of high-quality health care. Simulation has been integrated with patient safety activities in pediatric emergency medicine to improve knowledge, skills, and attitudes; teamwork and communication; systems and processes; and identification and mitigation of threats to safety. Simulation efforts, coordinated with those of key stakeholders, can be a powerful agent of change at the individual provider, team, and system levels. It is imperative that simulation activities be integrated within the systems infrastructure for maximal impact and dissemination of learnings.",2016,20/11/2018 14:34,14/04/2020 08:35,,185 - 192,,3,17,,,,,,,,,,,,,,,,,,,,,Quality of Health Care; Patient Safety; Patient Simulation; Emergency Medicine; Simulations; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IKCRABM6,journalArticle,2016,"Booker, Michael T.; O’Connell, Ryan J.; Desai, Bhushan; Duddalwar, Vinay A.; O'Connell, Ryan J",Quality Improvement With Discrete Event Simulation: A Primer for Radiologists.,Journal of the American College of Radiology,,1546-1440,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=113951822&site=ehost-live,"The application of simulation software in health care has transformed quality and process improvement. Specifically, software based on discrete-event simulation (DES) has shown the ability to improve radiology workflows and systems. Nevertheless, despite the successful application of DES in the medical literature, the power and value of simulation remains underutilized. For this reason, the basics of DES modeling are introduced, with specific attention to medical imaging. In an effort to provide readers with the tools necessary to begin their own DES analyses, the practical steps of choosing a software package and building a basic radiology model are discussed. In addition, three radiology system examples are presented, with accompanying DES models that assist in analysis and decision making. Through these simulations, we provide readers with an understanding of the theory, requirements, and benefits of implementing DES in their own radiology practices.",2016,20/11/2018 14:34,14/04/2020 08:34,,417 - 423,,4,13,,,,,,,,,,,,,,,,,,,,,United States; Systems Analysis; Computer Simulation; Software; 1; Models; Theoretical; Scales; Medical; Clinical Assessment Tools; Ferrans and Powers Quality of Life Index; Management; Private Practice Management – Administration; Quality Improvement – Administration; Specialties; Discrete event; 320,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, V3RW3XVB,journalArticle,2016,"Darragh, Amy R.; Lavender, Steve; Polivka, Barbara; Sommerich, Carolyn M.; Wills, Celia E.; Hittle, Bradley A.; Chen, Renee; Stredney, Donald L.",Gaming Simulation as Health and Safety Training for Home Health Care Workers.,Clinical Simulation in Nursing,,1876-1399,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=117095933&site=ehost-live,"Background The demand for home health care services is rapidly increasing and is driving a need for additional trained home health care professionals (HHPs). HHPs need effective training for managing personal health and safety hazards encountered when providing health care services in the home environment. The purpose of this article was to describe the process used for developing and evaluating an interactive virtual simulation training system (VSTS) to educate HHP. Sample Sixty-eight HHPs, including nurses, home health aides, occupational and physical therapists, administrators, and health and safety educators, participated in the study. Methods A mixed methods design that included an interdisciplinary, participatory design methodology was used to develop a VSTS to train HHP to identify and manage health and safety hazards in the home using a gaming simulation learning approach. Results This approach has yielded a training package that includes modules addressing electrical and fire hazards; environmental hazards; and lift, slip, and trip hazards routinely encountered by HHP. Conclusions Participatory methods are a useful and effective way to design a VSTS that is interactive, engaging, and informative.",2016,20/11/2018 14:34,14/04/2020 08:34,,328 - 335,,8,12,,,,,,,,,,,,,,,,,,,,,Research; Human; Teaching Methods; Simulations; Multimethod Studies; Interdisciplinary; Action Research; Electrical Safety; Fire Safety; Games; Health Education; Home Health Aides – Education; Safety – Education; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6T8TFZHM,journalArticle,2016,"Jessani, Nasreen S.; Boulay, Marc G.; Bennett, Sara C.",Do academic knowledge brokers exist? Using social network analysis to explore academic research-to-policy networks from six schools of public health in Kenya.,Health Policy & Planning,,0268-1080,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=116335202&site=ehost-live,"The potential for academic research institutions to facilitate knowledge exchange and influence evidence-informed decision-making has been gaining ground. Schools of public health (SPHs) may play a key knowledge brokering role-serving as agencies of and for development. Understanding academic-policymaker networks can facilitate the enhancement of links between policymakers and academic faculty at SPHs, as well as assist in identifying academic knowledge brokers (KBs). Using a census approach, we administered a sociometric survey to academic faculty across six SPHs in Kenya to construct academic-policymaker networks. We identified academic KBs using social network analysis (SNA) in a two-step approach: First, we ranked individuals based on (1) number of policymakers in their network; (2) number of academic peers who report seeking them out for advice on knowledge translation and (3) their network position as 'inter-group connectors'. Second, we triangulated the three scores and re-ranked individuals. Academic faculty scoring within the top decile across all three measures were classified as KBs. Results indicate that each SPH commands a variety of unique as well as overlapping relationships with national ministries in Kenya. Of 124 full-time faculty, we identified 7 KBs in 4 of the 6 SPHs. Those scoring high on the first measure were not necessarily the same individuals scoring high on the second. KBs were also situated in a wide range along the 'connector/betweenness' measure. We propose that a composite score rather than traditional 'betweenness centrality', provides an alternative means of identifying KBs within these networks. In conclusion, SNA is a valuable tool for identifying academic-policymaker networks in Kenya. More efforts to conduct similar network studies would permit SPH leadership to identify existing linkages between faculty and policymakers, shared linkages with other SPHs and gaps so as to contribute to evidence-informed health policies.",2016,20/11/2018 14:34,14/04/2020 08:34,,600 - 611,,5,31,,,,,,,,,,,,,,,,,,,,,Kenya; social network analysis; 00; Evidence-informed decision-making; evidence-to-policy; knowledge broker; schools of public health; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VLYL63DK,journalArticle,2017,"Salway, Sarah; Green, Judith",Towards a critical complex systems approach to public health.,Critical Public Health,,0958-1596,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=125035389&site=ehost-live,"The authors discuss various risks facing clinical research on complex and structural problems associated with public health. They state many bodies of relevant theory that could usefully guide system analysis are overlooked, which supposedly creates problems in analysis of complex systems, and mention that the large body of systems-informed and ongoing public health practice as another risk. They highlight the risk that the system boundaries are mis-specified, and key elements are left out.",2017,20/11/2018 14:34,14/04/2020 08:35,,523 - 524,,5,27,,,,,,,,,,,,,,,,,,,,,Health Policy; Research; Public Health; Professional Practice; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DZ5R5JF5,journalArticle,2016,"PHILLIPS, JANET M.; STALTER, ANN M.; DOLANSKY, MARY A.; LOPEZ, GLORIA MCKEE",FOSTERING FUTURE LEADERSHIP IN QUALITY AND SAFETY IN HEALTH CARE THROUGH SYSTEMS THINKING.,Journal of Professional Nursing,,8755-7223,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=112923672&site=ehost-live,"There is a critical need for leadership in quality and safety to reform today's disparate spectrum of health services to serve patients in complex health care environments. Nurse graduates of degree completion programs (registered nurse-bachelor of science in nursing [RN-BSN]) are poised for leadership due to their recent education and nursing practice experience. The authors propose that integration of systems thinking into RN-BSN curricula is essential for developing these much needed leadership skills. The purpose of this article is to introduce progressive teaching strategies to help nurse educators achieve the student competencies described in the second essential of the BSN Essentials document (American Association of Colleges of Nursing, 2009), linking them with the competencies in Quality and Safety Education for Nurses (QSEN; L. Cronenwett et al., 2007) using an author-created model for curricular design, the Systems-level Awareness Model. The Systems Thinking Tool (M. A. Dolansky & S. M. Moore, 2013) can be used to evaluate systems thinking in the RN-BSN curriculum.",2016,20/11/2018 14:34,14/04/2020 08:35,,15 - 24,,1,32,,,,,,,,,,,,,,,,,,,,,Curriculum; Safety; Quality Improvement; Teamwork; Collaboration; Education; Professional Competence; 1; Teaching Methods; Thinking; Patient Centered Care; Evidence-Based; Informatics; Leadership – Education; Nursing Practice; Outcomes of Education – Evaluation; Post-RN; System thinking; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6NGCCR5X,journalArticle,2016,"Zhang, Jin; Zhai, Shanshan; Liu, Hongxia; Stevenson, Jennifer Ann",Social network analysis on a topic-based navigation guidance system in a public health portal.,Journal of the Association for Information Science & Technology,,2330-1635,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=114604941&site=ehost-live,"We investigated a topic-based navigation guidance system in the World Health Organization portal, compared the link connection network and the semantic connection network derived from the guidance system, analyzed the characteristics of the 2 networks from the perspective of the node centrality (in_closeness, out_closeness, betweenness, in_degree, and out_degree), and provided the suggestions to optimize and enhance the topic-based navigation guidance system. A mixed research method that combines the social network analysis method, clustering analysis method, and inferential analysis methods was used. The clustering analysis results of the link connection network were quite different from those of the semantic connection network. There were significant differences between the link connection network and the semantic network in terms of density and centrality. Inferential analysis results show that there were no strong correlations between the centrality of a node and its topic information characteristics. Suggestions for enhancing the navigation guidance system are discussed in detail. Future research directions, such as application of the same research method presented in this study to other similar public health portals, are also included.",2016,20/11/2018 14:34,14/04/2020 08:35,,1068 - 1088,,5,67,,,,,,,,,,,,,,,,,,,,,World Health Organization; Public Health; User-Computer Interface; Social Networks; Human; Data Analysis Software; T-Tests; Consumer Health Information; Pearson's Correlation Coefficient; Semantics; World Wide Web; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5HJ486Y7,journalArticle,2018,"Nania, A.; Weir, A.; Weir, N.; Ritchie, G.; Rofe, C.; Van Beek, E.",CTPA protocol optimisation audit: challenges of dose reduction with maintained image quality.,Clinical Radiology,,0009-9260,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=127981444&site=ehost-live,"Aim: To assess computed tomography (CT) pulmonary angiography (CTPA) dose and image quality in a large teaching hospital, and subsequently, to optimise the protocol in order to reduce the dose without affecting image quality.Materials and Methods: Dose-length product (DLP), patient size, and objective quality parameters (contrast-to-noise ratio and signal-to-noise ratio on standardised levels) were recorded from 31 patients undergoing CTPA, where also a subjective image quality evaluation was carried out independently by three specialist cardiothoracic consultant radiologists. An equivalent objective and subjective quality assessment was carried out on a cohort of the same size in a different tertiary healthcare centre. Moreover, experimental tests using anthropomorphic chest phantoms were performed, using different scan parameters. In light of the above analysis, two of the scanner settings for CTPA were modified, i.e., the SureExposure pre-set was changed to ""Standard"" noise level, quantified with standard deviation (SD) of 19, and the minimum amperage setting lowered from 80 to 40 mA. A second cohort of patients using this new protocol was audited, following the same methodology.Results: The average DLP of patients undergoing CTPA was initially found to be higher than both local and national dose reference levels (DRLs; 559 versus 300 mGy·cm and 400 mGy·cm, respectively). The new protocol led to a reduction in average DLP (359 mGy·cm) while the image quality, assessed by three cardiothoracic consultant radiologists, was preserved.Conclusion: The CTPA protocol was implemented in the Royal Infirmary of Edinburgh resulting in significant dose reduction, and is now compliant with national and local DRLs. The image quality was maintained.",2018,20/11/2018 14:34,14/04/2020 08:35,,320.e1 - 320.e8,,3,73,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, K86K4ZTC,journalArticle,2015,"Collins, Sarah A; Alexander, Dana; Moss, Jacqueline",Nursing domain of CI governance: recommendations for health IT adoption and optimization.,Journal of the American Medical Informatics Association,,1067-5027,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109744656&site=ehost-live,"Context: There is a lack of recommended models for clinical informatics (CI) governance that can facilitate successful health information technology implementation.Objectives: To understand existing CI governance structures and provide a model with recommended roles, partnerships, and councils based on perspectives of nursing informatics leaders.Design, Setting, Participants: We conducted a cross-sectional study through administering a survey via telephone to facilitate semistructured interviews from June 2012 through November 2012. We interviewed 12 nursing informatics leaders, across the United States, currently serving in executive- or director-level CI roles at integrated health care systems that have pioneered electronic health records implementation projects.Results: We found the following 4 themes emerge: (1) Interprofessional partnerships are essential. (2) Critical role-based levels of practice and competencies need to be defined. (3) Integration into existing clinical infrastructure facilitates success. (4) CI governance is an evolving process. We described specific lessons learned and a model of CI governance with recommended roles, partnerships, and councils from the perspective of nursing informatics leaders.Conclusion: Applied CI work is highly interprofessional with patient safety implications that heighten the need for best practice models for governance structures, adequate resource allocation, and role-based competencies. Overall, there is a notable lack of a centralized CI group comprised of formally trained informaticians to provide expertise and promote adherence to informatics principles within EHR implementation governance structures. Our model of the nursing domain of CI governance with recommended roles, partnerships, and councils provides a starting point that should be further explored and validated. Not only can the model be used to understand, shape, and standardize roles, competencies, and structures within CI practice for nursing, it can be used within other clinical domains and by other informaticians.",2015,20/11/2018 14:34,14/04/2020 08:34,,697 - 706,,3,22,,,,,,,,,,,,,,,,,,,,,Cross-Sectional Studies; Interviews as Topic; Electronic Health Records/*organization & administration; 00; Clinical Competence/*standards; Clinical Informatics; Governance; Health Information Technology; Interprofessional; Medical Informatics/*organization & administration; Model development; Nursing Informatics; Nursing Informatics/*organization & administration/standards; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WPSCLI5C,journalArticle,2006,"Levy, DT; JE, Bauer; H, Lee",Opportunities and demands in public health systems. Simulation modeling and tobacco control: creating more robust public health policies.,American Journal of Public Health,,0090-0036,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106435151&site=ehost-live,"Although previous empirical studies have shown that tobacco control policies are effective at reducing smoking rates, such studies have proven of limited effectiveness in distinguishing how the effect of policies depend on the other policies in place, the length of adjustment period, the way the policy is implemented, and the demographic groups considered.An alternative and complementary approach to purely statistical equations is simulation models. We describe the SimSmoke simulation model and how we used it to assess tobacco control policy in a specific case study. Simulation models are not only useful for policy prediction and planning but also may help to broaden our understanding of the role of different public health policies within a complex, dynamic social system.",2006,20/11/2018 14:34,14/04/2020 08:34,,494 - 498,,3,96,,,,,,,,,,,,,,,,,,,,,"Humans; *Computer Simulation; Adolescent; Computer Simulation; Models, Statistical; Public Health; Smoking Cessation; Tobacco; Arizona; Health Policy/*legislation & jurisprudence; Smoking Prevention; Smoking/*epidemiology/*legislation & jurisprudence; 1; Models; Statistical; Adolescence; Behavioral Changes; Disease Surveillance; Health Policy – Evaluation; Smoking – Prevention and Control – In Adolescence; Smoking – Trends; Social Attitudes; 220",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FABQ63BY,journalArticle,2014,"Berndt, Janeen",Patient safety and simulation in prelicensure nursing education: An integrative review.,Teaching & Learning in Nursing,,1557-3087,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104126007&site=ehost-live,"Abstract: The Institute of Medicine (2003) called for healthcare educational reform to emphasize patient safety. The Quality and Safety Education for Nurses (2011) initiative responded to the call and defined quality and safety competencies and knowledge, skills, and attitudes necessary to achieve the competencies. The purpose of this review is to synthesize the evidence of simulation to teach safety in nursing education. The final appraisal included 17 articles. The evidence supports the use of simulation to teach patient safety competencies.",2014,20/11/2018 14:34,14/04/2020 08:34,,16 - 22,,1,9,,,,,,,,,,,,,,,,,,,,,Patient Safety; Nursing; Education; Outcomes of Education; Simulations; Institute of Medicine (U.S.); 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DE3DYXHI,journalArticle,2014,"Gulliford, Martin C.; Bhattarai, Nawaraj; Charlton, Judith; Rudisill, Caroline",Cost-effectiveness of a universal strategy of brief dietary intervention for primary prevention in primary care: population-based cohort study and Markov model.,Cost Effectiveness & Resource Allocation,,1478-7547,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104028097&site=ehost-live,"Background A healthy diet is associated with reduced risk of diabetes, cardiovascular disease and cancer. The study aimed to evaluate the cost-effectiveness of a universal strategy to promote healthy diet through brief intervention in primary care. Methods The research was informed by a systematic review of randomised trials which found that brief interventions in primary care may be associated with a 0.5 portion per day increase in fruit and vegetable consumption. A Markov model that included five long-term conditions (diabetes, coronary heart disease, stroke, colorectal cancer and depression) was developed. Empirical data from a large cohort of United Kingdom-based participants sampled from the Clinical Practice Research Datalink populated the model. Simulations compared an intervention promoting healthy diet over 5 years in healthy adults, and standard care in which there was no intervention. The annual cost of intervention, in the base case, was one family practice consultation per participant year. Health service costs were included and the model adopted a lifetime perspective. The primary outcome was net health benefit in quality adjusted life years (QALYs). Results A cohort of 262,704 healthy participants entered the model. Intervention was associated with an increase in life years lived free from physical disease of 41.9 (95% confidence interval - 17.4 to 101.0) per 1,000 participants entering the model (probability of increase 88.0%). New incidences of disease states were reduced by 28.4 (18.7 to 75.8) per 1,000, probability reduced 84.6%. Discounted incremental QALYs were 4.3 (-8.8 to 18.0) per 1,000, while incremental costs were £139,755 (£60,466 to 220,059) per 1,000. Net health benefits at £30,000 per QALY were -0.32 (-13.8 to 13.5) QALYs per 1,000 participants (probability cost-effective 47.9%). When the intervention was restricted to adults aged 50 to 74 years, net health benefits were 2.94 (-21.3 to 26.4) QALYs per 1000, probability increased 59.0%. Conclusions A universal strategy to promote healthy diet through brief intervention in primary care is unlikely to be cost-effective, even when delivered at low unit cost. A targeted strategy aimed at older individuals at higher risk of disease might be more cost-effective. More effective dietary change interventions are needed.",2014,20/11/2018 14:34,14/04/2020 08:34,,Jan-16,,1,12,,,,,,,,,,,,,,,,,,,,,Primary Health Care; United Kingdom; Prospective Studies; Sensitivity and Specificity; Life Expectancy; Confidence Intervals; Odds Ratio; 1; Descriptive Statistics; Human; Scales; Cost Benefit Analysis; Funding Source; Computer Simulation – Utilization; Diabetes Mellitus – Prevention and Control; Stroke – Prevention and Control; Clinical Trials – United Kingdom; Colorectal Neoplasms – Prevention and Control; Control Group; Coronary Disease – Prevention and Control; Food Habits; Nutritional Counseling – Methods; Predictive Validity; Preventive Health Care; Secondary Analysis; Markov; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, W4PWYM3I,journalArticle,2017,"Kaufman, Gerri; Bellerby, Ann; Kitching, Mike",Considering patient experience and evidence-based choice of medicines in medicines optimisation.,Nursing Standard,,0029-6570,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=123660920&site=ehost-live,"Medicines optimisation can be used by healthcare professionals to support patients to gain maximum benefit from their medicines, with two of the main principles being understanding the patient experience and ensuring medicines choice is evidence-based. Non-adherence is a significant issue in medicines management. Relational aspects of the patient experience, such as empathetic two-way communication between the healthcare professional and patient, the provision of clear information and shared decision-making, can have a positive influence on whether patients take their medicines as intended. In practice, the degree of influence exerted by evidence-based guidelines may result in tensions between the healthcare professional's choice of medicines and the patient's experience, while the prevalence of multimorbidity may mean that some patients are prescribed medicines from several clinical guidelines. This raises issues in relation to patient morbidity and safety, including the potential for issues with polypharmacy and an increased risk of adverse drug reactions. Medication review is an important tool for identifying the patient's medication burden, and deprescribing - the planned reduction of medicines that may no longer be effective - is emerging as a strategy to reduce polypharmacy. Further progress is required to increase patient involvement in the development of guidance for medicines management to enhance the quality of patient care, particularly in relation to their values and preferences. Similarly, further research is necessary to identify how patients make decisions about their medicines use.",2017,20/11/2018 14:34,14/04/2020 08:34,,54 - 63,,42,31,,,,,,,,,,,,,,,,,,,,,Decision Making; Polypharmacy; medicines management; patient safety; Education; 1; Patient Centered Care; Medication Compliance; Evidence-Based; Professional Practice; Continuing (Credit); Medication Management; Patient; Practice Guidelines; clinical guidelines; evidence-based practice; medication review; medicines optimisation; multimorbidity; patient experience; polypharmacy; Markov; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, W7PQBL3N,journalArticle,2006,"JB, Homer; GB, Hirsch",Opportunities and demands in public health systems. System dynamics model for public health: background and opportunities.,American Journal of Public Health,,0090-0036,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106435136&site=ehost-live,"The systems modeling methodology of system dynamics is well suited to address the dynamic complexity that characterizes many public health issues. The system dynamics approach involves the development of computer simulation models that portray processes of accumulation and feedback and that may be tested systematically to find effective policies for overcoming policy resistance.System dynamics modeling of chronic disease prevention should seek to incorporate all the basic elements of a modern ecological approach, including disease outcomes, health and risk behaviors, environmental factors, and health-related resources and delivery systems. System dynamics shows promise as a means of modeling multiple interacting diseases and risks, the interaction of delivery systems and diseased populations, and matters of national and state policy.",2006,20/11/2018 14:34,14/04/2020 08:34,,452 - 458,,3,96,,,,,,,,,,,,,,,,,,,,,Environment; Computer Simulation; Public Health; Policy Making; System dynamics; Systems Theory; Health Behavior; 1; Chronic Disease – Prevention and Control; Models; Health Care Delivery; Statistical; Outcomes (Health Care); Preventive Health Care; Causal Attribution; Chronic Disease – Complications; Chronic Disease – Mortality; Chronic Disease – Risk Factors; Ecology; 220,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2UVG2CGY,journalArticle,2006,"Y, Bar-Yam",Opportunities and demands in public health systems. Improving the effectiveness of health care and public health: a multisite complex systems analysis.,American Journal of Public Health,,0090-0036,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106435138&site=ehost-live,"The US health care system is struggling with a mismatch between the large, simple (low-information) financial flow and the complex (high-information) treatment of individual patients. Efforts to implement cost controls and industrial efficiency that are appropriate for repetitive tasks but not high-complexity tasks lead to poor quality of care.Multiscale complex systems analysis suggests that an important step toward relieving this structural problem is a separation of responsibility for 2 distinct types of tasks: medical care of individual patients and prevention/population health. These distinct tasks require qualitatively different organizational structures. The current use of care providers and organizations for both purposes leads to compromises in organizational process that adversely affect the ability of health care organizations to provide either individual or prevention/population services.Thus, the overall system can be dramatically improved by establishing 2 separate but linked systems with distinct organizational forms: (a) a high-efficiency system performing large-scale repetitive tasks such as screening tests, inoculations, and generic health care, and (b) a high-complexity system treating complex medical problems of individual patients.",2006,20/11/2018 14:34,14/04/2020 08:35,,459 - 466,,3,96,,,,,,,,,,,,,,,,,,,,,Cost Control; Quality of Health Care; Primary Health Care; Health Care Costs; Decision Making; Systems Analysis; Public Health; Systems Theory; Task Performance and Analysis; Health; 1; Clinical; Health Care Delivery; Organizational Change; Goals and Objectives; Organizational Efficiency; Preventive Health Care; Insurance; Organizational Restructuring; Organizational Structure; Reimbursement; 110; Complex System Analysis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YP5DF9EW,journalArticle,2016,"Røhne, Mette; Sandåker, Torjus; Ausen, Dag; Grut, Lisbet",Integrated planning tool for optimisation in municipal home care.,International Journal of Integrated Care (IJIC),,1568-4156,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=131858717&site=ehost-live,"Purpose: The objective is to improve collaboration and enhance quality of care services in municipal, home care services by implementing and developing an integrated planning tool making use of optimisation technology for better decision support. The project will through piloting and action based research establish knowledge on change in work processes to improve collaboration and efficiency. Context: A planning tool called Spider has been piloted in home care in Horten municipality since 2015 to address the challenges of planning to improve collaboration and quality and to increase utilisation of human resources. Planning of homecare services is a complex task that involves assigning 1) staff to patients, 2) routing staff visits, and 3) scheduling treatments while considering required competences, temporal precedencies between activities, competencies, preferences (of both caregivers and patients), labour laws, organisational policies and so on, within a restricted budget. Despite being a very complex optimisation task, planning is a 'manual' task with limited support from the electronic patient journal system resulting in inefficient solutions negatively affecting collaboration, service quality, quality of life, efficiency and costs. The project in Horten is unique and there is no similar tool available for home care. The project being an activity in the National Program for Welfare, started in one home care unit in 2015. Early 2016, the tool was implemented in all home care units being integrated with the electronic patient journal system (CosDoc) and the rostering system (Visma) in Horten. A Regional Research Funded project called OPTET is continuing research activities in Horten to develop new service processes and will include municipalities in Sandefjord, Porgrunn and Bergen. Methods: The project has used an exploratory design where research has been related to an ongoing innovation process in home care in Horten giving the required anchoring from management to do changes affecting users, relatives and employees. Methods for human centred design [1] combined with methods of innovation processes [2] have been applied and the pilot has been through several iterations with problem formulation, testing and evaluation to establish insight and knowledge on how work processes can be changed to improve collaboration and efficiency. Qualitative methods in terms of interviews and workshops are applied from action based research and design [3,4] and quantitative methods are used for evaluation. New service and work processes are described using Service Blueprint [5] and Business Process Modelling [6]. Results and Discussion: Results from Horten municipality are showing improved efficiency through 1) reduced planning time by 40%, 2) time savings due to improved planning by 10% and 3) improved service quality by reducing number of caregivers per user by 22%. Having Spider implemented in all home care units, evaluations will continue and also include evaluations of 4) gains by improved flexibility in resource allocation since Spider is enabling larger care units, 5) improved utilisation of resources and competence, 6) improved work professionality and employee satisfaction and 7) improved health and quality of life for users. The results from the study is likely to change the way home care is organised in the future.",2016,20/11/2018 14:34,14/04/2020 08:35,,01-Feb,,5 Supplement,16,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NYN8SBAJ,journalArticle,2016,"Buell, John M.",Advancing a Total-Systems Approach to Patient Safety. 3 Award-Winning Health Systems Share Their Initiatives.,Healthcare Executive,,0883-5381,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=113471807&site=ehost-live,The article presents the award-winning health systems and their initiatives that advance patient safety. President and chief executive office (CEO) Tejal Gandhi of the National Patient Safety Foundation admits that developing a quality and patient safety culture is daunting and can take a long time. Gandhi thinks that healthcare industry still lacks tactical tools to support healthcare CEOs in their initiatives.,2016,20/11/2018 14:34,14/04/2020 08:34,,22 - 22,,2,31,,,,,,,,,,,,,,,,,,,,,"United States; Quality of Health Care; Patient Safety; Safety Management/*organization & administration; Safety; *Efficiency, Organizational; Organizational Case Studies; *Patient Safety; Leadership; Organizational Culture; Multi-Institutional Systems; Ferrans and Powers Quality of Life Index; Multiinstitutional Systems; Organizational Efficiency; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ECZLUUVW,journalArticle,2001,"A, Kennedy; A, Rogers",Patient empowerment. Improving self-management skills: a whole systems approach.,British Journal of Nursing,,0966-0461,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106923330&site=ehost-live,"This article outlines the rationale behind an approach developed at the National Primary Care Research and Development Centre (NPCRDC) to improve patients' abilities to self-manage their conditions with the support of services provided by the NHS. The approach is systematic and requires involvement of patients in the development of information, changing access arrangements to health services and promoting a patient-centred approach to care. A programme of research and development is currently being undertaken at The University of Manchester by researchers based at NPCRDC to investigate the effectiveness of this approach. The evidence base for the strategy under investigation is discussed and proposals are made for the role of nurses as facilitators for the self-management agenda in the NHS.",2001,20/11/2018 14:34,14/04/2020 08:34,,734 - 737,,11,10,,,,,,,,,,,,,,,,,,,,,Decision Making; United Kingdom; Nurse-Patient Relations; Self Care; Patient Centered Care; Patient; Empowerment; Inflammatory Bowel Diseases; National Health Programs – United Kingdom; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 83F2SBJ9,journalArticle,2012,"RH, Steadman; YM, Huang","Simulation for quality assurance in training, credentialing and maintenance of certification.",Best Practice & Research: Clinical Anaesthesiology,,1521-6896,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104399977&site=ehost-live,"Simulation has become ubiquitous in medical education over the last decade. However, while many health-care professions and disciplines have embraced the use of simulation for training, its use for high-stakes testing and credentialing is less well established. This chapter explores the incorporation of simulation into training requirements and board certification, and its role for quality assurance of educational programmes and professional competence. Educational theories that underlie the use of simulation are described. The driving forces that support the simulation movement are outlined. Accreditation bodies have mandated simulation in training and maintenance of certification. It may be only a matter of time before simulation becomes one of the standards for performance assessment.",2012,20/11/2018 14:34,14/04/2020 08:35,,Mar-15,,1,26,,,,,,,,,,,,,,,,,,,,,Clinical Competence; Computer Simulation; Education; Accreditation; Medical; Certification; Anesthesiology – Education; Computer Assisted Instruction; Certification – Methods; Credentialing; Medical – Standards; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, AVXBHU65,journalArticle,2017,"Carmouche, Malinda Forsythe","Emergency obstetric simulation drills as a strategy to execute a multidisciplinary protocol with emphasis on safety culture evaluation, team synergy and team competency: A DNP project.","Emergency obstetric simulation drills as a strategy to execute a multidisciplinary protocol with emphasis on safety culture evaluation, team synergy & team competency: A DNP project",,9.78137E+12,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=124664876&site=ehost-live,"The aim of this Doctor of Nursing Practice Project was to implement emergency obstetric simulation to defend against patient safety risk linked to healthcare professional team dynamics in the care of obstetric patients as recommended by the Institute of Medicine (IOM), The Joint Commission (TJC) and the Quality and Safety Education for Nurses Initiative (QSEN). Team training is evidenced to reduce the mismanagement of emergency obstetric events by coaching providers in delivery of safe, effective and coordinated care during crises. The setting for this project was a hospital specializing in care of women and newborns. Hospitals, as the employers of healthcare professionals, have been uniquely positioned to be a training site for the multidisciplinary team. Simulation training has been beneficial to healthcare agencies attempting to improve outcomes. Imogene King's Theory of Goal Attainment was utilized as the theoretical support for this project. The Team Strategies and Tools to Enhance Performance and Patient Safety (TeamSTEPPS) method guided the project implementation. Emergency obstetric simulation training was implemented to investigate the performance of a multidisciplinary team. A feasibility study utilizing a pretest and post-test method was used to evaluate the impact of simulation training on safety culture, and team synergy. The Agency for Healthcare Research & Quality (AHRQ) Hospital Survey on Patient Safety Culture (HSOPSC), the TeamSTEPPS Teamwork Attitudes Questionnaire (T-TAQ) and Teamwork Perceptions Questionnaire (T-TPQ) were used to collect data from nurses and physicians (N = 24). Team competency was assessed with the Multidisciplinary Competency Checklist (MCC). Exposure of the team to obstetric emergency simulation showed some impact on patient safety culture, although not statistically significant. Data assessing safety culture revealed that participants in this study as compared to database respondents ranked higher in most of the survey's culture of safety domains. Exposure to emergency obstetric simulation although not statistically significant in changing attitudes and perceptions about teamwork, may still coach behavior. Repetitive simulation and reflective debriefing may help the team to amend executions and to recall correct actions during actual obstetric crisis.",2017,20/11/2018 14:34,14/04/2020 08:34,,01-Jan,,,,,,,,,,,,,,,,,,,,,,,,Safety; Hospitals; Health Personnel; Nursing; Education; Professional Competence; Human; Pretest-Posttest Design; Emergency Care; Program Implementation; Simulations; Questionnaires; Conceptual Framework; Pilot Studies; Checklists; Practice Guidelines; Multidisciplinary Care Team; Doctoral; King's Theory of Goal Attainment; Obstetric Emergencies; Synergy Model; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, SQW9U5T2,journalArticle,2010,"FS, Torres; AM, Crean; ET, Nguyen; N, Paul",Strategies for radiation-dose reduction and image-quality optimization in multidetector computed tomographic coronary angiography.,Canadian Association of Radiologists Journal,,0846-5371,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104970760&site=ehost-live,"The technological evolution of computed tomography (CT) in the last decade has placed CT coronary angiography (CTCA) in the spotlight of imaging modalities available to evaluate patients with coronary artery disease. Widespread utilisation of CTCA has generated concern from the medical community regarding potential health issues related to the significant radiation exposure associated with this method, and several modifications of the CTCA technique have been proposed to reduce the radiation exposure without affecting the diagnostic image quality. This review will discuss a practical approach to performing CTCA to ensure that the radiation dose is minimized while maintaining diagnostic image quality.",2010,20/11/2018 14:35,14/04/2020 08:34,,271 - 279,,5,61,,,,,,,,,,,,,,,,,,,,,Data Collection; Patient Care; Angiography – Methods; Calcium – Analysis; Coronary Disease – Radiography; Heart Rate; Quality Assurance; Radiation Injuries – Prevention and Control; Tomography – Methods; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TIHS9GLC,journalArticle,2010,"J, Guise; NK, Lowe; S, Deering; PO, Lewis; C, O'Haire; LK, Irwin; M, Blaser; LS, Wood; BG, Kanki",Mobile in situ obstetric emergency simulation and teamwork training to improve maternal-fetal safety in hospitals.,Joint Commission Journal on Quality & Patient Safety,,1553-7250,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105113045&site=ehost-live,"Background: Evidence from other high-risk industries has demonstrated that teamwork skills can be taught and effective teamwork may improve safety. Increasingly, health care providers, hospital administrators, and quality and safety professionals are considering simulation as a strategy to improve quality and patient safety. Mobile Obstetric Simulation and Team Training Program: A mobile obstetric emergency simulation and team training program was created to bring simulation technology and teamwork training used routinely in other high reliability fields directly to health care institutions. A mobile unit constituted a practical approach, given the expense of simulation equipment, the time required for staff to develop educational materials and simulation scenarios, and the need to have a standardized program to promote consistent evaluation across sites. Between 2007 and 2009, in situ simulation of obstetric emergencies and teamwork training was tested with more than 150 health care professionals in labor and delivery units across four rural and two community hospitals in Oregon. How Do Organizations Determine Which Type of Simulation Is Best for Them? Because simulation technologies are relatively costly to start and maintain, it can be challenging for hospitals and health care professionals to determine which format (send staff to a simulation center, develop in-house simulation program, develop a consortium of hospitals that run a simulation program, or use a mobile simulation program) is best for them. Conclusions: In situ simulation is an effective way to develop new skills, to maintain infrequently used clinical skills even among experienced clinical teams, and to uncover and address latent safety threats in the clinical setting.",2010,20/11/2018 14:35,14/04/2020 08:34,,443 - 453,,10,36,,,,,,,,,,,,,,,,,,,,,Staff Development; Quality of Health Care; Female; Patient Safety; Program Development; Pregnancy; Hospitals; Oregon; Educational Technology; Simulations; Curriculum Development; Teamwork – Education; Multidisciplinary Care Team; Course Content; Community – Oregon; Obstetric Emergencies – Education; Rural Areas; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VA88BRKE,journalArticle,2008,"KK, Miller; W, Riley; S, Davis; HE, Hansen",In situ simulation: a method of experiential learning to promote safety and team behavior.,Journal of Perinatal & Neonatal Nursing,,0893-2190,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105768765&site=ehost-live,"The healthcare system has an inconsistent record of ensuring patient safety. One of the main factors contributing to this poor record is inadequate interdisciplinary team behavior. This article describes in situ simulation and its 4 components–briefing, simulation, debriefing, and follow-up-as an effective interdisciplinary team training strategy to improve perinatal safety. The purpose of this manuscript is to describe the experiential nature of in situ simulation for the participants. Involved in a pilot study of 35 simulations in 6 hospitals with over 700 participants called, 'In Situ Simulation for Obstetric and Neonatal Emergencies,' conducted by Fairview Health Services in collaboration with the University of Minnesota's Academic Health Center.",2008,20/11/2018 14:35,14/04/2020 08:34,,105 - 113,,2,22,,,,,,,,,,,,,,,,,,,,,Female; Communication; Pregnancy; Models; Simulations; Patient Safety – Education; Teamwork – Education; Videorecording; Adverse Health Care Event – Prevention and Control; Anatomic; Multidisciplinary Care Team; Obstetric Emergencies – Education; Obstetric Care; Experiential Learning; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4E7D7WEU,journalArticle,2008,"E, Salas; KA, Wilson; EH, Lazzara; HB, King; JS, Augenstein; DW, Robinson; DJ, Birnbach",Simulation-based training for patient safety: 10 principles that matter.,Journal of Patient Safety,,1549-8417,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109849019&site=ehost-live,"Simulation-based training can improve patient care when factors influencing its design, delivery, evaluation, and transfer are taken into consideration. In this paper, we provide a number of principles and practical tips that organizations in health care can use to begin implementing effective simulation-based training as a way to enhance patient safety. We commend the health care community for their efforts thus far. We hope that the information provided in this paper will encourage thinking beyond the 'bells and whistles' of the simulation and bring to light full potential of simulation-based training in health care and patient safety.",2008,20/11/2018 14:35,14/04/2020 08:34,,03-Aug,,1,4,,,,,,,,,,,,,,,,,,,,,Program Evaluation; Program Development; Computer Simulation; Motivation; Group Processes; Organizational Culture; Patient Simulation; Teaching Methods; Simulations; Patient Safety – Education; Learning Environment; Clinical Competence – Education; Simulations – Classification; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, F56VN2PN,journalArticle,2008,"J, Merrill; M, Caldwell; ML, Rockoff; K, Gebbie; KM, Carley; S, Bakken; Merrill, Jacqueline; Caldwell, Michael; Rockoff, Maxine L; Gebbie, Kristine; Carley, Kathleen M; Bakken, Suzanne",Findings from an organizational network analysis to support local public health management.,Journal of Urban Health,,1099-3460,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105551743&site=ehost-live,"We assessed the feasibility of using organizational network analysis in a local public health organization. The research setting was an urban/suburban county health department with 156 employees. The goal of the research was to study communication and information flow in the department and to assess the technique for public health management. Network data were derived from survey questionnaires. Computational analysis was performed with the Organizational Risk Analyzer. Analysis revealed centralized communication, limited interdependencies, potential knowledge loss through retirement, and possible informational silos. The findings suggested opportunities for more cross program coordination but also suggested the presences of potentially efficient communication paths and potentially beneficial social connectedness. Managers found the findings useful to support decision making. Public health organizations must be effective in an increasingly complex environment. Network analysis can help build public health capacity for complex system management.",2008,20/11/2018 14:35,14/04/2020 08:34,,572 - 584,,4,85,,,,,,,,,,,,,,,,,,,,,"Surveys and Questionnaires; Risk Assessment; Public Health/*methods; Feasibility Studies; Models, Organizational; Management Information Systems; 1; Human; Questionnaires; Pilot Studies; Management; Public Health – Methods; Decision Support Systems; Information Retrieval – Methods; Management – Administration; Medical Informatics – Administration; Medical Informatics – Methods; New York; *Database Management Systems; Decision Support Systems, Management/*organization & administration; Information Storage and Retrieval/*methods; Medical Informatics/*methods/*organization & administration; network analysis; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RVT3WDPQ,journalArticle,2009,"SCS, Gomes Junior; RT, Almeida",Simulation model for estimating the cancer care infrastructure required by the public health system.,Revista Panamericana de Salud Publica,,,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105364001&site=ehost-live,"OBJECTIVE: To develop a simulation model using public data to estimate the cancer care infrastructure required by the public health system in the state of Sao Paulo, Brazil. METHOD: Public data from the Unified Health System database regarding cancer surgery, chemotherapy, and radiation therapy, from January 2002-January 2004, were used to estimate the number of cancer cases in the state. The percentages recorded for each therapy in the Hospital Cancer Registry of Brazil were combined with the data collected from the database to estimate the need for services. Mixture models were used to identify subgroups of cancer cases with regard to the length of time that chemotherapy and radiation therapy were required. A simulation model was used to estimate the infrastructure required taking these parameters into account. RESULTS: The model indicated the need for surgery in 52.5% of the cases, radiation therapy in 42.7%, and chemotherapy in 48.5%. The mixture models identified two subgroups for radiation therapy and four subgroups for chemotherapy with regard to mean usage time for each. These parameters allowed the following estimated infrastructure needs to be made: 147 operating rooms, 2 653 operating beds, 297 chemotherapy chairs, and 102 radiation therapy devices. These estimates suggest the need for a 1.2-fold increase in the number of chemotherapy services and a 2.4-fold increase in the number of radiation therapy services when compared with the parameters currently used by the public health system. CONCLUSION: A simulation model, such as the one used in the present study, permits better distribution of health care resources because it is based on specific, local needs.",2009,20/11/2018 14:35,14/04/2020 08:35,,113 - 119,,2,25,,,,,,,,,,,,,,,,,,,,,"Public Sector; *Public Health; *Models, Statistical; *Computer Simulation; Prospective Studies; Health Services Needs and Demand; Brazil; 1; Descriptive Statistics; Human; Simulations; Health Resource Allocation; Neoplasms – Epidemiology; Neoplasms – Surgery; Neoplasms – Therapy; Surgical Equipment and Supplies; Delivery of Health Care/*organization & administration/*standards; Neoplasms/*therapy; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IA3U8IM9,journalArticle,2007,"S, Woodard; L, Archer; E, Zell; O, Ronveaux; M, Birmingham",Design and simulation study of the immunization Data Quality Audit (DQA),Annals of Epidemiology,,1047-2797,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105847969&site=ehost-live,"The goal of the Data Quality Audit (DQA) is to assess whether the Global Alliance for Vaccines and Immunization-funded countries are adequately reporting the number of diphtheria-tetanus-pertussis immunizations given, on which the 'shares' are awarded. Given that this sampling design is a modified two-stage cluster sample (modified because a stratified, rather than a simple, random sample of health facilities is obtained from the selected clusters); the formula for the calculation of the standard error for the estimate is unknown. An approximated standard error has been proposed, and the first goal of this simulation is to assess the accuracy of the standard error. Results from the simulations based on hypothetical populations were found not to be representative of the actual DQAs that were conducted. Additional simulations were then conducted on the actual DQA data to better access the precision of the DQ with both the original and the increased sample sizes.",2007,20/11/2018 14:35,14/04/2020 08:35,,628 - 633,,8,17,,,,,,,,,,,,,,,,,,,,,World Health Organization; Computer Simulation; Africa; Probability; Cluster Analysis; Burkina Faso; Pakistan; Human; Developing Countries; Study Design; Immunization – Utilization; Diphtheria-Tetanus-Pertussis Vaccine – Administration and Dosage; Diphtheria-Tetanus-Pertussis Vaccine – Supply and Distribution; Drug Utilization – Methods; Guideline Adherence – Statistics and Numerical Data; Immunization Programs – Administration; Immunization Programs – Utilization; Quality Control (Technology); Western; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, G49RHZ5X,journalArticle,2004,"KJ, Carter; F, Castro; E, Kessler; BA, Erickson",Simulation of breast cancer screening: quality assessment of two protocols.,Journal for Healthcare Quality: Promoting Excellence in Healthcare,,1062-2551,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106679034&site=ehost-live,"Healthcare professionals must make breast cancer screening decisions without the help of clear answers in current medical knowledge. This study used computer simulation to evaluate two screening protocols. The American Cancer Society (ACS) protocol comprising self-breast examination, professional breast examination and annual mammography was evaluated versus annual mammography alone. The effective frequency of mammography and the cost in the ACS protocol doubles the cost of mammography alone. Breast self-examination and clinical breast examination contributes to increased cost without any added health effects. These study results could be applied by healthcare professionals to assist their decision making for breast cancer screening.",2004,20/11/2018 14:35,14/04/2020 08:34,,31 - 38,,6,26,,,,,,,,,,,,,,,,,,,,,Health Policy; Female; Computer Simulation; Neoplasm Staging; American Cancer Society; Human; Protocols; Funding Source; Quality Assessment; Breast Examination; Breast Neoplasms – Prevention and Control; Breast Self-Examination; Cancer Screening – Economics; Cancer Screening – Methods; Mammography; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, V9SZZKBA,journalArticle,2002,"JC, Messenger; JS, Rumsfeld; JD, Carroll; J, Combes; SYJ, Chen",Enhancing patient safety during cardiac catheterization using simulation-based training.,Topics in Health Information Management,,1065-0989,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106833322&site=ehost-live,"Recent efforts to improve patient safety have included the creation of the Agency for Healthcare Research and Quality that has funded a number of projects aimed at enhancing patient safety. In this article, we summarize a collaborative research project that uses a cardiovascular simulator for the performance of cardiac catheterization for training and assessment of patient safety-related procedural skills, knowledge, and clinical decision making. The purpose of this project is to demonstrate, evaluate, and disseminate an innovative training program for health care providers using medical simulation to enhance knowledge about patient safety practices and to promote a positive safety environment. Copyright © 2002 by Aspen Publishers, Inc.",2002,20/11/2018 14:35,14/04/2020 08:34,,82 - 93,,2,23,,,,,,,,,,,,,,,,,,,,,Patient Satisfaction; Patient Safety; Computer Simulation; Descriptive Statistics; Human; Teaching Methods; Data Analysis Software; Clinical; Funding Source; Chi Square Test; Fisher's Exact Test; Heart Catheterization – Education; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, G4Q7KUYA,journalArticle,2004,"LB, Landrum; SL, Baker",Managing complex systems: performance management in public health.,Journal of Public Health Management & Practice,,1078-4659,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106755839&site=ehost-live,"The complexity of mobilizing and managing systems-wide public health responses has prompted Turning Point's Performance Management National Excellence Collaborative, funded by the Robert Wood Johnson Foundation, to develop a conceptual framework for performance management in public health. The framework has four integrated parts: (1) performance standards, (2) performance measures, (3) reporting of progress, and (4) a quality improvement process. The Collaborative based its framework on evidence gathered through a survey of current state performance management practices, a literature review, and its investigation of current practice models. This balanced and cohesive management model can be constructively used by public health programs, organizations, and community and state public health systems.",2004,20/11/2018 14:35,14/04/2020 08:34,,13 - 18,,1,10,,,,,,,,,,,,,,,,,,,,,Quality Improvement; Collaboration; Organizational Objectives; Professional Competence; 1; Models; Theoretical; Clinical Indicators; Biological Warfare – Prevention and Control; Change Management; Disaster Planning – Standards; Health and Welfare Planning – Standards; Management – Evaluation; Performance Measurement Systems – Standards; Public Health Administration – Administration; Quality of Health Care – Evaluation; Terrorism – Prevention and Control; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, D9ZBA963,journalArticle,2001,"RA, Bryant; BS, Rolstaf",Utilizing a systems approach to implement pressure ulcer prediction and prevention.,Ostomy Wound Management,,0889-5899,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106898672&site=ehost-live,"Efficient, effective patient care is an objective shared by all healthcare settings and systems. It is generally accepted that using national clinical guidelines facilitates pursuit of this objective. However, implementation of a guideline, or any process improvement activity, requires a systematic, collaborative approach from which new processes can be purposefully designed. This article reviews systems theory, presents the steps for process improvement using the Plan/Do/Check/Act cycle, and references a recent statewide quality improvement study conducted by the authors in collaboration with Stratis Health, a Minnesota Medical Peer Review Organization.",2001,20/11/2018 14:35,14/04/2020 08:35,,26 - 36,,9,47,,,,,,,,,,,,,,,,,,,,,Humans; Program Evaluation; United States; Health Personnel/education; Risk Factors; Risk Assessment; *Systems Analysis; Quality Improvement; Systems Theory; Practice Guidelines as Topic/*standards; Minnesota; Total Quality Management/*organization & administration; Predictive Value of Tests; Beds/standards; Biomechanical Phenomena; Nursing Assessment; Nursing Audit; Patient Education as Topic/standards; Pressure Ulcer/*etiology/*prevention & control; Process Assessment (Health Care)/*organization & administration; Professional Review Organizations; Skin Care/methods/nursing/standards; Program Implementation; Multiinstitutional Systems; Practice Guidelines; Multidisciplinary Care Team; Program Planning; Pressure Ulcer – Prevention and Control; United States Agency for Healthcare Research and Quality; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4VTCXN69,journalArticle,2001,"VC, Kennedy; FI, Moore",A systems approach to public health workforce development.,Journal of Public Health Management & Practice,,1078-4659,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106886303&site=ehost-live,"During the 1990s, several distinct but interrelated efforts to strengthen the public health infrastructure were launched. Defining public health work in terms of core functions and essential services, these efforts focused on the competence of the workforce and the performance of public health agencies. The systems approach offered here highlights the relationships and interdependencies among these three components of public health practice: (1) the work, (2) the worker, and (3) the work setting. The model suggests that advances in public health workforce development may require major public health organizational development efforts.",2001,20/11/2018 14:35,14/04/2020 08:35,,17 - 22,,4,7,,,,,,,,,,,,,,,,,,,,,Systems Analysis; Technology; Task Performance and Analysis; Professional Competence; Models; Theoretical; Health and Welfare Planning; Organizational Structure; Public Health Administration – Administration; Public Health Administration – Manpower; Workforce – Evaluation; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, C6IAMRGM,journalArticle,2000,"JM, Eisenberg",Continuing education meets the learning organization: the challenge of a systems approach to patient safety.,Journal of Continuing Education in the Health Professions,,0894-1912,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107007629&site=ehost-live,"Since the release of the report of the Institute of Medicine on medical errors and patient safety in November 1999, health policy makers and health care leaders in several nations have sought solutions that will improve the safety of health care. This attention to patient safety has highlighted the importance of a learning approach and a systems approach to quality measurement and improvement. Balanced with the need for public disclosure of performance, confidential reporting with, feedback is one of the prime ways that nations such as the United States, Canada, the United Kingdom, and Australia have approached this challenge. In the United States, the Quality Interagency Coordination Task Force has convened federal agencies that are involved in health care quality improvement for a coordinated initiative. Based on an investment in a strong research foundation in health care quality measurement and improvement, there are eight key lessons for continuing education if it is to parlay the interest in patient safety into enhanced continuing education and quality improvement in learning health care systems. The themes for these lessons are (1) informatics for information, (2) guidelines as learning tools, (3) learning from opinion leaders, (4) learning from the patient, (5) decision support systems, (6) the team learning together, (7) learning organizations, and (8) just-in-time and point-of-care delivery.",2000,20/11/2018 14:35,14/04/2020 08:34,,197 - 207,,4,20,,,,,,,,,,,,,,,,,,,,,Patient Safety; Program Development; Quality Improvement; Systems Theory; Education; Health Care Delivery; Treatment Errors – Prevention and Control; Organizational Change; Systems Design; Medical; Physicians; Behavioral Changes; United States Agency for Healthcare Research and Quality; Continuing; Continuing Education Providers; Learning Methods; Physician's Role; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RZ6T6KL5,journalArticle,2013,"Merrill, Jacqueline A; Deegan, Michael; Wilson, Rosalind V; Kaushal, Rainu; Fredericks, Kimberly",A system dynamics evaluation model: implementation of health information exchange for public health reporting.,Journal of the American Medical Informatics Association,,1067-5027,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104291105&site=ehost-live,"OBJECTIVE: To evaluate the complex dynamics involved in implementing electronic health information exchange (HIE) for public health reporting at a state health department, and to identify policy implications to inform similar implementations. MATERIALS AND METHODS: Qualitative data were collected over 8 months from seven experts at New York State Department of Health who implemented web services and protocols for querying, receipt, and validation of electronic data supplied by regional health information organizations. Extensive project documentation was also collected. During group meetings experts described the implementation process and created reference modes and causal diagrams that the evaluation team used to build a preliminary model. System dynamics modeling techniques were applied iteratively to build causal loop diagrams representing the implementation. The diagrams were validated iteratively by individual experts followed by group review online, and through confirmatory review of documents and artifacts. RESULTS: Three casual loop diagrams captured well-recognized system dynamics: Sliding Goals, Project Rework, and Maturity of Resources. The findings were associated with specific policies that address funding, leadership, ensuring expertise, planning for rework, communication, and timeline management. DISCUSSION: This evaluation illustrates the value of a qualitative approach to system dynamics modeling. As a tool for strategic thinking on complicated and intense processes, qualitative models can be produced with fewer resources than a full simulation, yet still provide insights that are timely and relevant. CONCLUSIONS: System dynamics techniques clarified endogenous and exogenous factors at play in a highly complex technology implementation, which may inform other states engaged in implementing HIE supported by federal Health Information Technology for Economic and Clinical Health (HITECH) legislation.",2013,20/11/2018 14:35,14/04/2020 08:34,,e131 - 8,,,20,,,,,,,,,,,,,,,,,,,,,Health Policy; United States; Evaluation; Systems Analysis; Public Health; Policy; *Public Health Administration; State Medicine/*organization & administration; System Dynamics; 1; Human; Health and Welfare Planning; New York; Public Health Administration – Administration; American Recovery and Reinvestment Act; National Health Programs – Administration; Health Information Systems/*organization & administration; Health Information Exchange; Regional Medical Programs/*organization & administration; 320,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6AN2TQG5,journalArticle,2010,"R, Kneebone","Simulation, safety and surgery.",Quality & Safety in Health Care,,1475-3898,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104950996&site=ehost-live,"OBJECTIVES: This paper explores the place of simulation in contemporary healthcare education and training, highlighting the challenges of recreating complex clinical settings which can support the development of competent, rounded and caring practitioners, and address issues around human factors as well as technical skill. It frames the relationship between clinical and simulation-based practice as a mutually dependent, two-way process. DISCUSSION: According to this view, simulation is less like a photograph of clinical care than a painting of it-a process that requires selection and interpretation. The paper presents simulation as a canvas on which to paint this picture. To be effective, simulation must mirror the essentials of a clinical setting without reproducing every detail. After highlighting key issues with current approaches to simulation, the paper considers how authenticity and perceived realism can be heightened through innovative uses of technology and design, putting forward a conceptual framework based on the notion of 'circles of focus.' The paper then outlines the concept of Distributed Simulation, using low-cost, portable yet immersive environments to address limitations of access to dedicated facilities. CONCLUSION: The paper concludes by considering theoretical and practical implications of these innovations, focussing especially on surgery and other craft specialties.",2010,20/11/2018 14:36,14/04/2020 08:35,,i47 - 52,,,19,,,,,,,,,,,,,,,,,,,,,Clinical Competence; Patient Safety; Resource Allocation; Time Factors; Surgery; Continuity of Patient Care; Professional-Patient Relations; Diffusion of Innovation; Risk Management; Patient Simulation – Utilization; Teaching Methods; Conceptual Framework; Medical; Health Personnel – Education; Work Environment; Operative – Education; Ethics; Holistic Care; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IZXTXZ5C,journalArticle,2005,"S, Petula",Can applying systems theory improve quality in healthcare systems?,Journal for Healthcare Quality: Promoting Excellence in Healthcare,,1062-2551,,http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106459908&site=ehost-live,"The relationship between the healthcare delivery system, health promotion, and quality of care is dynamic, critical, and at times fraught with error, confusion, and frustration. The responsibility of healthcare workers to promote the well-being of their patients and provide high-quality care can be undermined by the complexities of the healthcare system. This article provides a substantive answer to the question 'Can the application of a systems-theory framework support quality improvement in healthcare systems?' Narrative discussion, concept mapping, and an integrative review of relevant literature demonstrate that the deliberate application of systems theory within an interdisciplinary framework supports healthcare system behaviors that can reduce error, improve quality, and promote health.",2005,20/11/2018 14:36,14/04/2020 08:35,,W6 - 2,,6,27,,,,,,,,,,,,,,,,,,,,,Health Promotion; Interprofessional Relations; Quality Improvement; Process Assessment (Health Care); Systems Theory; Health Care Delivery; Conceptual Framework; Multidisciplinary Care Team; Health Care Errors – Prevention and Control; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ZNWHTUP7,journalArticle,2013,"Iyngkaran, P.; Majoni, V.; Nadarajan, K.; Haste, M.; Battersby, M.; Ilton, Marcus; Harris, M.",AUStralian Indigenous Chronic Disease Optimisation Study (AUSI-CDS) prospective observational cohort study to determine if an established chronic disease health care model can be used to deliver better heart failure care among remote Indigenous Australians: Proof of concept-study rationale and protocol.,"Heart, lung & circulation",,1444-2892 1443-9506,10.1016/j.hlc.2013.04.001,,"BACKGROUND: The congestive heart failure syndrome has increased to epidemic proportions and is cause for significant morbidity and mortality. Indigenous patients suffer a greater prevalence with greater severity. Upon diagnosis patients require regular follow-up with medical and allied health services. Patients are prescribed life saving, disease modifying and symptom relieving therapies. This can be an overwhelming experience for patients. To compound this, remoteness, differentials in conventional health care and services pose special problems for Indigenous clients in accessing care. Additional barriers of language, culture, socio-economic disadvantage, negative attitudes towards establishment, social stereotyping, stigma and discrimination act as barriers to improved care. Recent focus supported by clinical evidence support the role of chronic disease self-management programs. A patient focused, problem identification, goal setting and psychosocial modification based program should in principal highlight these issues and help tailor a patient focused comprehensive care plan to complement guideline based care. At present there are no Indigenous focused chronic disease self-management programs. There is a need for research on ways to provide chronic disease management to this group. We therefore designed a study to assess a model of patient focussed comprehensive care for Indigenous Australians with heart failure. STUDY DESIGN: AUSI-CDS is a prospective, cohort, observational study to evaluate the efficacy of the standard ""Flinders Program of Chronic Condition Management"" for Indigenous patients with chronic heart failure. Eligible patients will be Indigenous, suffering from chronic heart failure, in the Northern Territory. The primary end-point is the satisfaction score based on the PACIC. The study will recruit 20 patients and is expected to last 12 months. SUMMARY: The rationale and design of the AUSI-CDS using the Flinders Model is described.",2013-11,21/11/2018 09:40,14/04/2020 08:34,,930-939,,11,22,,Heart Lung Circ,,,,,,,,eng,Copyright (c) 2013 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ). All rights reserved.,,,,,,PMID: 23689164,,,,"Humans; Female; Male; *Models, Biological; Chronic Disease; Severity of Illness Index; *Delivery of Health Care; Prevalence; Heart failure; Australia/epidemiology; 00; 6MWT; Alice Springs Hospital; ASH; BNP; Brain Natriuretic Peptide; C&R; CDSMP; CFPI; CHF; chronic disease self management program; congestive heart failure; Cue and Response; Flinders Medical Centre; Flinders Model of Self Care; Flinders Program of Chronic Condition Management; FMC; FMSC; heart failure; Heart Failure/epidemiology/*physiopathology/therapy; HF; Indigenous; Northern Territory; Northern Territory Department of Health and Families; NT; NT DHCS; P&G; PACIC; Partners in Health; patient assessment and chronic illness care satisfaction questionnaire; PHC; PIH; primary health care records; Problems and Goals; Protocol; RDH; Royal Darwin Hospital; Rural; Self-management; six minute walk test; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2K2S4R7M,journalArticle,2012,"McGorman, Laura; Marsh, David R.; Guenther, Tanya; Gilroy, Kate; Barat, Lawrence M.; Hammamy, Diaa; Wansi, Emmanuel; Peterson, Stefan; Hamer, Davidson H.; George, Asha",A health systems approach to integrated community case management of childhood illness: methods and tools.,The American journal of tropical medicine and hygiene,,1476-1645 0002-9637,10.4269/ajtmh.2012.11-0758,,"Integrated community case management (iCCM) of childhood illness is an increasingly popular strategy to expand life-saving health services to underserved communities. However, community health approaches vary widely across countries and do not always distribute resources evenly across local health systems. We present a harmonized framework, developed through interagency consultation and review, which supports the design of CCM by using a systems approach. To verify that the framework produces results, we also suggest a list of complementary indicators, including nine global metrics, and a menu of 39 country-specific measures. When used by program managers and evaluators, we propose that the framework and indicators can facilitate the design, implementation, and evaluation of community case management.",2012-11,21/11/2018 09:40,14/04/2020 08:34,,69-76,,5 Suppl,87,,Am J Trop Med Hyg,,,,,,,,eng,,,,,,,PMID: 23136280 PMCID: PMC3748525,,,,"Humans; Government Programs; 1; Developing Countries; Case Management/*standards; Community Health Services/*standards; Delivery of Health Care, Integrated/*standards; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, M7BBK5YA,journalArticle,2012,"Geary, Carol R.; Schumacher, Karen L.",Care transitions: integrating transition theory and complexity science concepts.,ANS. Advances in nursing science,,1550-5014 0161-9268,10.1097/ANS.0b013e31826260a5,,"Care transitions, defined as hospital discharge or movement from one health care setting to another, are currently a major concern of health care providers and policy makers. Extensive empirical research has been conducted on care transitions, but the theoretical foundations are rarely made explicit. We propose that integrating concepts on complex adaptive systems from complexity science with classic theory on transitions in nursing provides a powerful new lens through which to study care transitions and improve transition outcomes. We summarize concepts from both theoretical approaches, propose an expanded model of transitions, and apply the model to the transition from hospital to home.",2012-09,21/11/2018 09:40,14/04/2020 08:34,,236-248,,3,35,,ANS Adv Nurs Sci,,,,,,,,eng,,,,,,,PMID: 22869210,,,,"Humans; Outcome and Process Assessment (Health Care); Attitude of Health Personnel; Organizational Innovation; Home Care Services/*organization & administration; 00; *Models, Nursing; Community Health Nursing/*organization & administration; Nursing Staff, Hospital/*organization & administration; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9HYHRH4P,journalArticle,2010,"Anguita Sanchez, Manuel; Jimenez-Navarro, Manuel; Crespo, Marisa; Alonso-Pulpon, Luis; de Teresa, Eduardo; Castro-Beiras, Alfonso; Roig, Eulalia; Artigas, Remei; Zapata, Antonio; Lopez de Ulibarri, Ignacio; Muniz, Javier",Effect of a training program for primary care physicians on the optimization of beta-blocker treatment in elderly patients with heart failure.,Revista espanola de cardiologia,,1579-2242 0300-8932,,,"INTRODUCTION AND OBJECTIVES: Underuse of betablockers may contribute to elevated mortality in chronic heart failure. The aim of this study was to determine whether a specific interventional training program for primary care physicians would help optimize the use of beta-blockers in elderly chronic heart failure patients. METHODS: This randomized comparative study included 627 patients aged 70 years or more who were discharged consecutively from 53 Spanish hospitals with a principal diagnosis of chronic heart failure. In total, 292 health-care centers in the catchment areas of these hospitals were randomly assigned to two groups: one group of 146 centers carried out an interventional training program on beta-blocker use for primary care physicians belonging to the centers assigned to training, and 146 centers served as a control group. The main outcome variable was the percentage of patients who were receiving a beta-blocker at the maximum or maximum tolerated dose 3 months after hospital discharge. RESULTS: The patients' mean age was 78+/-5 years and 42% were women. There was no difference between the groups in demographic characteristics, clinical care, or treatment at discharge. The percentage of patients who received beta-blockers at the maximum tolerated dose 3 months after discharge was greater in the training group (49% vs. 38%; P=.014). Being treated in the training group was an independent predictor of receiving a beta-blocker at the MTD (odds ratio=2.46; 95% confidence interval, 1.29-4.69; P< .001). CONCLUSIONS: Implementation of an interventional training program on beta-blocker treatment for primary care physicians improved the use of these medications in elderly chronic heart failure patients.",2010-06,21/11/2018 09:40,14/04/2020 08:34,,677-685,,6,63,,Rev Esp Cardiol,,,,,,,,eng,,,,,,,PMID: 20515625,,,,"Humans; Female; Male; Aged; Chronic Disease; Single-Blind Method; *Primary Health Care; 00; *Education, Medical; Adrenergic beta-Antagonists/*therapeutic use; Heart Failure/*drug therapy; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, J6AUCNKI,journalArticle,2008,"Schindler, Jay V.; Mraz, Tom",Agent-based modeling for real-time decision-support for point-of-distribution managers during influenza mass vaccination.,AMIA ... Annual Symposium proceedings. AMIA Symposium,,1942-597X 1559-4076,,,"This project examines the use of an agent-based modeling tool and development environment to provide real-time decision support and resource allocation for managers and staff of point-of-distribution (POD) locations conducting mass vaccination for epidemic influenza. The simulation testing environment allows depicting the physical POD environment, staffing location and behaviors, patient flow, and resource monitoring and distribution. Various POD optimizations are analyzed and discussed in light of recent public health recommended layouts and resource deployment.",06/11/2008,21/11/2018 09:40,14/04/2020 08:34,,1124,,,,,AMIA Annu Symp Proc,,,,,,,,eng,,,,,,,PMID: 18999052,,,,"Humans; Computer Simulation; Models, Theoretical; Decision Support Systems, Clinical/*organization & administration; Computer Systems; 00; Georgia; Influenza Vaccines/*therapeutic use; Influenza, Human/*epidemiology/*prevention & control; Mass Vaccination/*organization & administration; Point-of-Care Systems/*organization & administration; Review",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YGVUKDPB,journalArticle,2007,"Tannen, Richard L.; Weiner, Mark G.; Xie, Dawei; Barnhart, Kurt",A simulation using data from a primary care practice database closely replicated the women's health initiative trial.,Journal of clinical epidemiology,,0895-4356 0895-4356,10.1016/j.jclinepi.2006.10.012,,"OBJECTIVE: In contrast to prior observational studies, hormone replacement therapy (HRT) did not prevent coronary heart disease in the Women's Health Initiative Randomized Controlled Trial (WHI RCT). To assess the validity of a novel observational study design, we compared the WHI RCT with a simulation using data from the United Kingdom General Practice Research Database (GPRD). STUDY DESIGN AND SETTING: A cohort from GPRD was used to simulate the WHI RCT by replicating, to the extent possible, all aspects of the RCT except randomization. The study included 37,730 Unexposed and 13,658 Exposed women treated with estrogen and norgestrel. RESULTS: Myocardial infarction (adjusted hazard ratio 0.95 [0.78-1.16]) was not decreased significantly in the GPRD Exposed group. Similar to the WHI RCT, stroke, venous thromboembolic events, and breast cancer were increased; and colorectal cancer was decreased. Although death appeared to decrease in the total cohort, it was unaltered in a subset of subjects without missing data on baseline covariates. CONCLUSION: A structured comparison using data from GPRD was largely concordant with the WHI RCT and did not show a cardioprotective effect of HRT. These findings further generalize the results of WHI and reinforce the potential utility of this analytic approach.",2007-07,21/11/2018 09:40,14/04/2020 08:35,,686-695,,7,60,,J Clin Epidemiol,,,,,,,,eng,,,,,,,PMID: 17573984,,,,"Humans; Randomized Controlled Trials as Topic; Female; Middle Aged; Aged; Cohort Studies; United Kingdom; *Primary Health Care; Databases, Factual; 1; *Estrogen Replacement Therapy; Breast Neoplasms/epidemiology/prevention & control; Coronary Disease/epidemiology/*prevention & control; Myocardial Infarction/epidemiology/prevention & control; Postmenopause; Stroke/epidemiology/prevention & control; Thrombosis/epidemiology/prevention & control; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, D98DV4S2,journalArticle,2006,"Matlow, A. G.; Wright, J. G.; Zimmerman, B.; Thomson, K.; Valente, M.",How can the principles of complexity science be applied to improve the coordination of care for complex pediatric patients?,Quality & safety in health care,,1475-3901 1475-3898,10.1136/qshc.2005.014605,,"Clinical and technological advances in medicine have resulted in more patients requiring multidisciplinary care and coordination of services. This is particularly challenging in pediatrics, given the dependency of children. Coordination of care is a key ingredient of quality care; when suboptimal, clinical outcomes and satisfaction can suffer. In this article we view coordination of care through the lens of complexity science in an effort to find new solutions to this healthcare challenge.",2006-04,21/11/2018 09:40,14/04/2020 08:34,,85-88,,2,15,,Qual Saf Health Care,,,,,,,,eng,,,,,,,PMID: 16585105 PMCID: PMC2464825,,,,"Humans; Interprofessional Relations; Child; Comorbidity; Health Services Research/*methods; Quality Assurance, Health Care/*organization & administration; Patient Care Planning; Systems thinking; 1; *Disabled Children; *Specialization; Continuity of Patient Care/*organization & administration; Medicine/*organization & administration; Patient-Centered Care/*organization & administration; Pediatrics/*organization & administration/standards; Referral and Consultation; ******To read; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JASCPP99,journalArticle,2018,"Leppin, Aaron L.; Okamoto, Janet M.; Organick, Paige W.; Thota, Anjali D.; Barrera-Flores, Francisco J.; Wieland, Mark L.; McCoy, Rozalina G.; Bonacci, Robert P.; Montori, Victor M.",Applying Social Network Analysis to Evaluate Implementation of a Multisector Population Health Collaborative That Uses a Bridging Hub Organization.,Frontiers in public health,,2296-2565 2296-2565,10.3389/fpubh.2018.00315,,"Background: Multisector collaboratives are increasingly popular strategies for improving population health. To be comprehensive, collaboratives must coordinate the activities of many organizations across a geographic region. Many policy-relevant models encourage creation and use of centralized hub organizations to do this work, yet there is little guidance on how to evaluate implementation of such hubs and track their network reach. We sought to demonstrate how social network analysis (SNA) could be used for this purpose. Methods: Through formative research, we defined and conceptualized key characteristics of a bridging hub network and identified a set of candidate measures-(1) network membership, (2) network interaction, (3) role and reach of the bridging hub, and (4) network collaboration-to evaluate its implementation within a pre-determined geographic region of Southeast Minnesota, USA. We then developed and administered a survey to assess outcomes as part of a SNA. We commented on the feasibility and usefulness of the methods. Results: The initial surveyed network consisted of 50 healthcare organizational sites and 50 community organizations representing sectors of public health, education, research, health promotion, social services, and long-term care and supports. Fifty-three of these organizations responded to the survey. The network's level of collaboration was ""Cooperation"" (level 2 of 5) and reported levels of collaboration varied by organization. Thirty-eight additional, unsurveyed organizations were identified as collaborators by respondents, pushing the theoretical network denominator up to 138 organizations. These additional organizations included grocery stores, ambulance services, and smaller, independent healthcare and community-based services focused on meeting the needs of underserved populations. The bridging hub organization had the highest betweenness centrality and was in good position to bridge healthcare and the community, although its organizational reach was estimated at only 51%. The SNA methods were feasible and useful for identifying opportunities and guiding implementation. Conclusions: Bridging hub organizations are not likely to link-or even be aware of-all relevant organizations in a geographic region at initial implementation. SNA may be a useful method for evaluating the value and reach of a bridging hub organization and guiding ongoing implementation efforts. Trial registration: http://ClinicalTrials.gov; #NCT03046498.",2018,21/11/2018 09:42,14/04/2020 08:34,,315,,,6,,Front Public Health,,,,,,,,eng,,,,,,,PMID: 30450355 PMCID: PMC6224340,,,,social network analysis; 1; community based programs; health promotion; partnerships; population health; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 94JMZG2R,journalArticle,2018,"McGetrick, Jennifer Ann; Raine, Kim D.; Wild, T. Cameron; Nykiforuk, Candace I. J.",Advancing Strategies for Agenda Setting by Health Policy Coalitions: A Network Analysis of the Canadian Chronic Disease Prevention Survey.,Health communication,,1532-7027 1041-0236,10.1080/10410236.2018.1484267,,"Health in all policies can address chronic disease morbidity and mortality by increasing population-level physical activity and healthy eating, and reducing tobacco and alcohol use. Both governmental and nongovernmental policy influencers are instrumental for health policy that modifies political, economic, and social environments. Policy influencers are informed and persuaded by coalitions that support or oppose changing the status quo. Empirical research examining policy influencers' contact with coalitions, as a social psychological exposure with health policy outcomes, can benefit from application of health communication theories. Accordingly, we analyzed responses to the 2014 Chronic Disease Prevention Survey for 184 Canadian policy influencers employed in provincial governments, municipalities, large workplaces, school boards, and the media. In addition to contact levels with coalitions, respondents' jurisdiction, organization, and ideology were analyzed as potential moderators. Calculating authority score centrality using network analysis, we determined health policy supporters to be more central in policy influencer networks, and theorized their potential to impact health policy public agenda setting via priming and framing processes. We discuss the implications of our results as presenting opportunities to more effectively promote health policy through priming and framing by coordinating coalitions across risk behaviors to advance a societal imperative for chronic disease prevention.",11/06/2018,21/11/2018 09:42,14/04/2020 08:34,,01-Oct,,,,,Health Commun,,,,,,,,eng,,,,,,,PMID: 29889549,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JHLAHL92,journalArticle,2018,"Choi, Jung Eun; Kim, Mi So",Exploring the Knowledge Structure of Nursing Care for Older Patients With Delirium: Keyword Network Analysis.,"Computers, informatics, nursing : CIN",,1538-9774 1538-2931,10.1097/CIN.0000000000000424,,"Prevention of delirium is considered a critical part of the agenda for patient safety and an indicator of healthcare quality for older patients. As the incidence rate of delirium for older patients has increased in recent years, there has been a significant expansion in knowledge relevant to nursing care. The purposes of this study were to analyze the knowledge structure and trends in nursing care for older adults with delirium based on a keyword network analysis, and to provide a foundation for future research. Data analysis showed that knowledge structure in this area consists of three themes of research: postoperative acute care for older patients with delirium, prevention of delirium for older patients in intensive care units, and safety management for the improvement of outcomes for patients with delirium. Through research trend analysis, we found that research on care for patients with delirium has achieved both quantitative and qualitative improvements over the last decades. Concerning future research, we propose the expansion of patient- and family-centered care, community care, specific nursing interventions, and the integration of new technology into care for patients with delirium. These results provide a reference framework for understanding and developing nursing care for older adults with delirium.",2018-05,21/11/2018 09:42,14/04/2020 08:34,,216-224,,5,36,,Comput Inform Nurs,,,,,,,,eng,,,,,,,PMID: 29494362,,,,"Humans; Female; Male; Middle Aged; Aged; Quality Improvement; *Research Design; *Health Knowledge, Attitudes, Practice; Intensive Care Units; 00; *Nursing Care; Delirium/*prevention & control/*therapy; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 96S26KAL,journalArticle,2017,"Serag-Bolos, Erini S.; Miranda, Aimon C.; Gelot, Shyam R.; Dharia, Sheetal P.; Shaeer, Kristy M.",Assessing students' knowledge regarding the roles and responsibilities of a pharmacist with focus on care transitions through simulation.,Currents in pharmacy teaching & learning,,1877-1300 1877-1297,10.1016/j.cptl.2017.03.020,,"BACKGROUND AND PURPOSE: To evaluate the impact of a pharmacist-focused transitions of care (TOC) simulation on students' perceptions and knowledge of pharmacist roles in the healthcare continuum. Educational Activity and Setting: Two simulations, highlighting pharmacist roles in various practice settings, were conducted within the Pharmaceutical Skills courses in the third-year doctor of pharmacy curriculum. Patient cases were built utilizing electronic medical records (EMR). Students' knowledge was assessed before and after the simulations regarding pharmacist involvement in medication reconciliation, reduction in patient readmissions, reduction of inappropriate medication use, roles and communication on an interprofessional team, and involvement with health information technology (HIT) during care transitions. FINDINGS: Fifty-one third-year pharmacy students were anonymously evaluated prior to and following the simulation to assess changes in knowledge and perceptions during the fall semester. Thirty-two (62.7%) students completed the pre-simulation and 21 (41.2%) students completed the post-simulation assessments, respectively. In the spring semester, 40 (80%) students completed the pre-simulation and 23 (46%) students finished the post-simulation assessments. Students predominately had community pharmacy work experience (n=28, 55%). Overall, students enjoyed the variety of pharmacist-led encounters throughout the simulation and assessments demonstrated an increase in knowledge after the simulations. SUMMARY: TOC simulations enhance students' understanding of the significant impact that pharmacists have in ensuring continuity of care as members of an interdisciplinary team.",2017-07,21/11/2018 09:42,14/04/2020 08:35,,616-625,,4,9,,Curr Pharm Teach Learn,,,,,,,,eng,Published by Elsevier Inc.,,,,,,PMID: 29233434,,,,"Humans; Adult; Female; Male; *Simulation; *Students, Pharmacy; Curriculum/trends; 00; *Care transitions; *Electronic medical record; *Health information technology; *Pharmacy; *Pharmacy education; *Professional Role; Education, Pharmacy/methods; Educational Measurement/*methods; Medication Reconciliation; Pharmacists; Simulation Training/methods; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3WA3X43U,journalArticle,2018,"Gartner, Daniel; Zhang, Yiye; Padman, Rema",Cognitive workload reduction in hospital information systems : Decision support for order set optimization.,Health care management science,,1386-9620 1386-9620,10.1007/s10729-017-9406-6,,"Order sets are a critical component in hospital information systems that are expected to substantially reduce physicians' physical and cognitive workload and improve patient safety. Order sets represent time interval-clustered order items, such as medications prescribed at hospital admission, that are administered to patients during their hospital stay. In this paper, we develop a mathematical programming model and an exact and a heuristic solution procedure with the objective of minimizing physicians' cognitive workload associated with prescribing order sets. Furthermore, we provide structural insights into the problem which lead us to a valid lower bound on the order set size. In a case study using order data on Asthma patients with moderate complexity from a major pediatric hospital, we compare the hospital's current solution with the exact and heuristic solutions on a variety of performance metrics. Our computational results confirm our lower bound and reveal that using a time interval decomposition approach substantially reduces computation times for the mathematical program, as does a K -means clustering based decomposition approach which, however, does not guarantee optimality because it violates the lower bound. The results of comparing the mathematical program with the current order set configuration in the hospital indicates that cognitive workload can be reduced by about 20.2% by allowing 1 to 5 order sets, respectively. The comparison of the K -means based decomposition with the hospital's current configuration reveals a cognitive workload reduction of about 19.5%, also by allowing 1 to 5 order sets, respectively. We finally provide a decision support system to help practitioners analyze the current order set configuration, the results of the mathematical program and the heuristic approach.",2018-06,21/11/2018 09:42,14/04/2020 08:34,,224-243,,2,21,,Health Care Manag Sci,,,,,,,,eng,,,,,,,PMID: 28551859,"

8th IMA Health Conference, London, ENGLAND, MAR 21-23, 2016

",,,"Humans; Models, Theoretical; *Decision Support Systems, Clinical; Optimization; Physicians; 00; *Drug Prescriptions; *Workload; Analytical modeling; Cognitive Reserve; Health informatics/health information systems/medical IS; Healthcare information systems; Heuristics; Hospital Information Systems; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3TKGW3EW,journalArticle,2017,"Heiser Rosenberg, Carol E.; Terhaar, Mary F.; Ascenzi, Judith A.; Walbert, Anna; Kokoszka, K. Michelle; Perretta, Julianne S.; Miller, Marlene R.",Becoming Parent and Nurse: High-Fidelity Simulation in Teaching Ambulatory Central Line Infection Prevention to Parents of Children with Cancer.,Joint Commission journal on quality and patient safety,,1553-7250 1553-7250,10.1016/j.jcjq.2017.02.007,,"BACKGROUND: Ambulatory central-line infections in children with cancer are life-threatening. Infections are two to three times more frequent in outpatients than inpatients, for whom evidence-based bundles have decreased morbidity. Most cancer care now takes place at home, where parents perform many of the same tasks as nurses. However, parents often feel stressed and unprepared. To address this, high-fidelity simulation, which has been effective for teaching novice nurses, was evaluated for parent central-line education. METHODS: In a feasibility study using a pretest/posttest design, after completion of usual central-line education, parents participated in a high-fidelity simulation practice session. Parents were assessed in three domains: (1) knowledge of infection prevention; (2) psychomotor skill competence; and (3) ability to recognize health care provider nonadherence to best practices. Parents also completed a 5-point Likert simulation experience survey. RESULTS: A convenience sample of 17 parents participated between December 2015 and March 2016. Knowledge median scores increased from pre- to posttest from 10 to 15 of 16 points possible (p /= 50 Years in Japan: Results of a Markov Model Analysis.,Dermatology and therapy,,2193-8210,10.1007/s13555-018-0236-3,,"INTRODUCTION: The aim of this study was to compare the public health impact of introducing two herpes zoster (HZ) vaccines into the vaccination programs for the Japanese population aged >/= 50 years: a single-dose Varicella Vaccine Live (VVL) or a two-dose adjuvanted Recombinant Zoster Vaccine (RZV). METHODS: A multi-cohort static Markov model was developed to follow age cohorts (50-59,",2018-06,21/11/2018 10:01,14/04/2020 08:35,,269-284,,2,8,,Dermatol Ther (Heidelb),,,,,,,,eng,,,,,,,PMID: 29680914 PMCID: PMC6002317,,,,Markov model; 00; Herpes zoster (HZ); HZ complications; Live attenuated vaccine; Postherpetic neuralgia; Public health impact; Recombinant zoster vaccine; Varicella zoster virus; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VQCL6S2J,journalArticle,2017,"Dieckmann, Peter; Patterson, Mary; Lahlou, Saadi; Mesman, Jessica; Nystrom, Patrik; Krage, Ralf",Variation and adaptation: learning from success in patient safety-oriented simulation training.,"Advances in simulation (London, England)",,2059-0628 2059-0628,10.1186/s41077-017-0054-1,,"Simulation is traditionally used to reduce errors and their negative consequences. But according to modern safety theories, this focus overlooks the learning potential of the positive performance, which is much more common than errors. Therefore, a supplementary approach to simulation is needed to unfold its full potential. In our commentary, we describe the learning from success (LFS) approach to simulation and debriefing. Drawing on several theoretical frameworks, we suggest supplementing the widespread deficit-oriented, corrective approach to simulation with an approach that focusses on systematically understanding how good performance is produced in frequent (mundane) simulation scenarios. We advocate to investigate and optimize human activity based on the connected layers of any setting: the embodied competences of the healthcare professionals, the social and organizational rules that guide their actions, and the material aspects of the setting. We discuss implications of these theoretical perspectives for the design and conduct of simulation scenarios, post-simulation debriefings, and faculty development programs.",2017,21/11/2018 10:01,14/04/2020 08:34,,21,,,2,,Adv Simul (Lond),,,,,,,,eng,,,,,,,PMID: 29450022 PMCID: PMC5806267,,,,Patient safety; Simulation; 00; Activity theory; Debriefings; Faculty development; Installation theory; Mundane practice; Safety II; Scenarios; Video reflexivity; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 454D6GTC,journalArticle,2017,"Williams, Brett; Reddy, Priya; Marshall, Stuart; Beovich, Bronwyn; McKarney, Lesley",Simulation and mental health outcomes: a scoping review.,"Advances in simulation (London, England)",,2059-0628 2059-0628,10.1186/s41077-016-0035-9,,"Background: A scoping review was conducted in order to map and determine the gaps in literature on the impact of simulation as an educational approach to improve mental health care outcomes. As it became apparent that no literature existed on this topic, the study aimed to examine the educational impact of simulation on mental health education. Methods: An established five-stage scoping methodology was used: (1) identification of the research question, (2) identification of relevant studies, (3) study selection, (4) charting the data and (5) collation, summarising and reporting of results. CINAHL, ProQuest, PubMed, MEDLINE, EMBASE and PsychINFO databases were searched. These databases were deemed to represent a majority of the literature while accommodating for the particular search strategy used for this review. Websites that provide grey literature were also searched for articles of relevance. Results: A total of 48 articles were included in this review, with a considerable portion of studies conducted in the USA and UK. Others were conducted in an array of locations including Australia, Canada, Iran and Taiwan. Of the included articles, seven groups of simulation methods (including standardised patients, virtual reality and manikins as patients) were evident, with standardised patients being most prominent. Conclusions: Literature is lacking to evidence the benefit of simulation on mental health patient outcomes. However, the available literature suggests a variety of simulation-based education, and training methods are currently being used within mental healthcare education. The findings do suggest some methods of simulation, such as the use of standardised patients, are more commonly used in education and have been deemed as effective to assist in mental health education. As no article specifically examining the mental health outcomes of patients treated by health professionals taught by simulation was identified, the educational outcomes outlined in this paper may be used to inform further research, incorporating mental health patient outcomes.",2017,21/11/2018 10:01,14/04/2020 08:35,,2,,,2,,Adv Simul (Lond),,,,,,,,eng,,,,,,,PMID: 29450003 PMCID: PMC5806484,,,,Students; Patient simulation; 00; Health occupations; Manikin; Mental health; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2EVU3EFQ,journalArticle,2017,"Kim, Minji; Choi, Mona; Youm, Yoosik",[Semantic Network Analysis of Online News and Social Media Text Related to Comprehensive Nursing Care Service].,Journal of Korean Academy of Nursing,,2093-758X 2005-3673,10.4040/jkan.2017.47.6.806,,"PURPOSE: As comprehensive nursing care service has gradually expanded, it has become necessary to explore the various opinions about it. The purpose of this study is to explore the large amount of text data regarding comprehensive nursing care service extracted from online news and social media by applying a semantic network analysis. METHODS: The web pages of the Korean Nurses Association (KNA) News, major daily newspapers, and Twitter were crawled by searching the keyword 'comprehensive nursing care service' using Python. A morphological analysis was performed using KoNLPy. Nodes on a 'comprehensive nursing care service' cluster were selected, and frequency, edge weight, and degree centrality were calculated and visualized with Gephi for the semantic network. RESULTS: A total of 536 news pages and 464 tweets were analyzed. In the KNA News and major daily newspapers, 'nursing workforce' and 'nursing service' were highly rated in frequency, edge weight, and degree centrality. On Twitter, the most frequent nodes were 'National Health Insurance Service' and 'comprehensive nursing care service hospital.' The nodes with the highest edge weight were 'national health insurance,' 'wards without caregiver presence,' and 'caregiving costs.' 'National Health Insurance Service' was highest in degree centrality. CONCLUSION: This study provides an example of how to use atypical big data for a nursing issue through semantic network analysis to explore diverse perspectives surrounding the nursing community through various media sources. Applying semantic network analysis to online big data to gather information regarding various nursing issues would help to explore opinions for formulating and implementing nursing policies.",2017-12,21/11/2018 10:01,14/04/2020 08:34,,806-816,,6,47,,J Korean Acad Nurs,,,,,,,,kor,(c) 2017 Korean Society of Nursing Science,,,,,,PMID: 29326411,,,,Humans; Internet; Semantics; 00; *Semantic Web; *Social Media; Communications media; Newspaper article; Newspapers as Topic; Nursing Care/*statistics & numerical data; Nursing services; Social media; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DIL6LP6E,journalArticle,2018,"Holtrop, Jodi Summers; Ruland, Sandra; Diaz, Stephanie; Morrato, Elaine H.; Jones, Eric",Using Social Network Analysis to Examine the Effect of Care Management Structure on Chronic Disease Management Communication Within Primary Care.,Journal of general internal medicine,,1525-1497 0884-8734,10.1007/s11606-017-4247-z,,"BACKGROUND: Care management and care managers are becoming increasingly prevalent in primary care medical practice as a means of improving population health and reducing unnecessary care. Care managers are often involved in chronic disease management and associated transitional care. In this study, we examined the communication regarding chronic disease care within 24 primary care practices in Michigan and Colorado. We sought to answer the following questions: Do care managers play a key role in chronic disease management in the practice? Does the prominence of the care manager's connectivity within the practice's communication network vary by the type of care management structure implemented? METHODS: Individual written surveys were given to all practice members in the participating practices. Survey questions assessed demographics as well as practice culture, quality improvement, care management activities, and communication regarding chronic disease care. Using social network analysis and other statistical methods, we analyzed the communication dynamics related to chronic disease care for each practice. RESULTS: The structure of chronic disease communication varies greatly from practice to practice. Care managers who were embedded in the practice or co-located were more likely to be in the core of the communication network than were off-site care managers. These care managers also had higher in-degree centrality, indicating that they acted as a hub for communication with team members in many other roles. DISCUSSION: Social network analysis provided a useful means of examining chronic disease communication in practice, and highlighted the central role of care managers in this communication when their role structure supported such communication. Structuring care managers as embedded team members within the practice has important implications for their role in chronic disease communication within primary care.",2018-05,21/11/2018 10:01,14/04/2020 08:34,,612-620,,5,33,,J Gen Intern Med,,,,,,,,eng,,,,,,,PMID: 29313225 PMCID: PMC5910335,,,,Social network analysis; 1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LSLLTY2W,journalArticle,2018,"Ellis, Diane M.; Meakim, Colleen; Prieto, Patricia; O'Connor, Melissa",Transitional Care Experience in Home Health: Exposing Students to Care Transitions Through Scenarios and Simulation.,Nursing education perspectives,,1536-5026 1536-5026,10.1097/01.NEP.0000000000000148,,"Chronically ill older adults are at risk for avoidable adverse events especially during care transitions, the transfer to one care setting or one level of care to another. Because of the expected increase in the older adult population, increased demand for transitional care is anticipated. Despite the consistent call for expanded competencies in care transitions, nursing education has not incorporated these concepts into nursing curricula. To fill this gap, Villanova University developed patient care scenarios and simulations incorporating standardized patients to demonstrate the needs, risks, and potential complications associated with transitioning patients from acute care to home.",2018-02,21/11/2018 10:01,14/04/2020 08:34,,48-50,,1,39,,Nurs Educ Perspect,,,,,,,,eng,,,,,,,PMID: 29267179,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4GNEK4YH,journalArticle,2018,"Wanneveich, Mathilde; Jacqmin-Gadda, Helene; Dartigues, Jean-Francois; Joly, Pierre",Projections of health indicators for chronic disease under a semi-Markov assumption.,Theoretical population biology,,1096-0325 0040-5809,10.1016/j.tpb.2017.11.006,,"Chronic diseases are a growing public health problem due to the population aging. Their economic, social and demographic burden will worsen in years to come. Up to now, the method used to provide projections and assess the future disease burden makes a non-homogeneous Markov assumption in an illness-death model. Both age and calendar year have been taken into account in all parameter estimations, but the time spent with the disease was not considered. This work develops the method with a semi-Markov assumption to model mortality among the diseased and considering the time spent with the disease. The method is applied to estimate several health indicators for dementia in France in 2030. We find that mortality among the individuals with dementia depends on age, calendar year and disease duration, and it is greater for men than for women at all ages. The projections for 2030 suggest a 27% increase of the number of dementia cases. The model proposed in this work has flexible assumptions that make it adaptable to provide projections for various diseases.",2018-02,21/11/2018 10:01,14/04/2020 08:34,,83-90,,,119,,Theor Popul Biol,,,,,,,,eng,Copyright (c) 2017 Elsevier Inc. All rights reserved.,,,,,,PMID: 29258742,,,,1; *Dementia; *Epidemiology; *Multi-states model; *Projection; *semi-Markov; Markov; 210,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, C9RD4JRJ,journalArticle,2018,"Laker, Lauren F.; Torabi, Elham; France, Daniel J.; Froehle, Craig M.; Goldlust, Eric J.; Hoot, Nathan R.; Kasaie, Parastu; Lyons, Michael S.; Barg-Walkow, Laura H.; Ward, Michael J.; Wears, Robert L.",Understanding Emergency Care Delivery Through Computer Simulation Modeling.,Academic emergency medicine : official journal of the Society for Academic Emergency Medicine,,1553-2712 1069-6563,10.1111/acem.13272,,"In 2017, Academic Emergency Medicine convened a consensus conference entitled, ""Catalyzing System Change through Health Care Simulation: Systems, Competency, and Outcomes."" This article, a product of the breakout session on ""understanding complex interactions through systems modeling,"" explores the role that computer simulation modeling can and should play in research and development of emergency care delivery systems. This article discusses areas central to the use of computer simulation modeling in emergency care research. The four central approaches to computer simulation modeling are described (Monte Carlo simulation, system dynamics modeling, discrete-event simulation, and agent-based simulation), along with problems amenable to their use and relevant examples to emergency care. Also discussed is an introduction to available software modeling platforms and how to explore their use for research, along with a research agenda for computer simulation modeling. Through this article, our goal is to enhance adoption of computer simulation, a set of methods that hold great promise in addressing emergency care organization and design challenges.",2018-02,21/11/2018 10:01,14/04/2020 08:34,,116-127,,2,25,,Acad Emerg Med,,,,,,,,eng,(c) 2017 by the Society for Academic Emergency Medicine.,,,,,,PMID: 28796433 PMCID: PMC5805575,"

Academic Emergency Medicine Consensus Conference on Catalyzing System Change Through Healthcare Simulation - Systems, Completency, and Outcomes, Orlando, FL, MAY 16, 2017

",,,1; ******To read; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JRIKQX7Y,journalArticle,2017,"Luo, Jing; Tian, Lingling; Luo, Lei; Yi, Hong; Wang, Fahui",Two-Step Optimization for Spatial Accessibility Improvement: A Case Study of Health Care Planning in Rural China.,BioMed research international,,2314-6141,10.1155/2017/2094654,,"A recent advancement in location-allocation modeling formulates a two-step approach to a new problem of minimizing disparity of spatial accessibility. Our field work in a health care planning project in a rural county in China indicated that residents valued distance or travel time from the nearest hospital foremost and then considered quality of care including less waiting time as a secondary desirability. Based on the case study, this paper further clarifies the sequential decision-making approach, termed ""two-step optimization for spatial accessibility improvement (2SO4SAI)."" The first step is to find the best locations to site new facilities by emphasizing accessibility as proximity to the nearest facilities with several alternative objectives under consideration. The second step adjusts the capacities of facilities for minimal inequality in accessibility, where the measure of accessibility accounts for the match ratio of supply and demand and complex spatial interaction between them. The case study illustrates how the two-step optimization method improves both aspects of spatial accessibility for health care access in rural China.",2017,21/11/2018 10:01,14/04/2020 08:34,,2094654,,,2017,,Biomed Res Int,,,,,,,,eng,,,,,,,PMID: 28484707 PMCID: PMC5412212,,,,Humans; Female; Male; China; *Rural Population; 00; *Delivery of Health Care/organization & administration/standards; *Rural Health; *Rural Health Services/organization & administration/standards; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5QAX2P5A,journalArticle,2017,"Streeter, Robin A.; Zangaro, George A.; Chattopadhyay, Arpita",Perspectives: Using Results from HRSA's Health Workforce Simulation Model to Examine the Geography of Primary Care.,Health services research,,1475-6773 0017-9124,10.1111/1475-6773.12663,,"OBJECTIVE: Inform health planning and policy discussions by describing Health Resources and Services Administration's (HRSA's) Health Workforce Simulation Model (HWSM) and examining the HWSM's 2025 supply and demand projections for primary care physicians, nurse practitioners (NPs), and physician assistants (PAs). DATA SOURCES: HRSA's recently published projections for primary care providers derive from an integrated microsimulation model that estimates health workforce supply and demand at national, regional, and state levels. PRINCIPAL FINDINGS: Thirty-seven states are projected to have shortages of primary care physicians in 2025, and nine states are projected to have shortages of both primary care physicians and PAs. While no state is projected to have a 2025 shortage of primary care NPs, many states are expected to have only a small surplus. CONCLUSIONS: Primary care physician shortages are projected for all parts of the United States, while primary care PA shortages are generally confined to Midwestern and Southern states. No state is projected to have shortages of all three provider types. Projected shortages must be considered in the context of baseline assumptions regarding current supply, demand, provider-service ratios, and other factors. Still, these findings suggest geographies with possible primary care workforce shortages in 2025 and offer opportunities for targeting efforts to enhance workforce flexibility.",2017-02,21/11/2018 10:01,14/04/2020 08:34,,481-507,,,52 Suppl 1,,Health Serv Res,,,,,,,,eng,(c) Published 2017. This article is a U.S. Government work and is in the public domain in the USA.,,,,,,PMID: 28127767 PMCID: PMC5269550,,,,"Humans; United States; *Primary care; Health Services Needs and Demand/*statistics & numerical data; 00; *health workforce; *scope of practice; *shortage; *training; Geography; Nurse Practitioners/*statistics & numerical data; Personnel Staffing and Scheduling/statistics & numerical data; Physician Assistants/*statistics & numerical data; Physicians, Primary Care/*statistics & numerical data; Primary Health Care/*manpower/*statistics & numerical data; Professional Practice Location/*statistics & numerical data; Review",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HVHXVGUV,journalArticle,2017,"Weinfeld, Jeffrey M.; Mishori, Ranit",Toward Electronic Health Record Optimization: Learning From the User Experience.,The Journal of ambulatory care management,,1550-3267 0148-9917,10.1097/JAC.0000000000000172,,,2017-03,21/11/2018 10:01,14/04/2020 08:35,,02-May,,1,40,,J Ambul Care Manage,,,,,,,,eng,,,,,,,PMID: 27902546,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KVIL2GEM,journalArticle,2017,"Cresswell, Kathrin M.; Lee, Lisa; Mozaffar, Hajar; Williams, Robin; Sheikh, Aziz",Sustained User Engagement in Health Information Technology: The Long Road from Implementation to System Optimization of Computerized Physician Order Entry and Clinical Decision Support Systems for Prescribing in Hospitals in England.,Health services research,,1475-6773 0017-9124,10.1111/1475-6773.12581,,"OBJECTIVE: To explore and understand approaches to user engagement through investigating the range of ways in which health care workers and organizations accommodated the introduction of computerized physician order entry (CPOE) and computerized decision support (CDS) for hospital prescribing. STUDY SETTING: Six hospitals in England, United Kingdom. STUDY DESIGN: Qualitative case study. DATA COLLECTION: We undertook qualitative semi-structured interviews, non-participant observations of meetings and system use, and collected organizational documents over three time periods from six hospitals. Thematic analysis was initially undertaken within individual cases, followed by cross-case comparisons. FINDINGS: We conducted 173 interviews, conducted 24 observations, and collected 17 documents between 2011 and 2015. We found that perceived individual and safety benefits among different user groups tended to facilitate engagement in some, while other less engaged groups developed resistance and unsanctioned workarounds if systems were perceived to be inadequate. We identified both the opportunity and need for sustained engagement across user groups around system enhancement (e.g., through customizing software) and the development of user competencies and effective use. CONCLUSIONS: There is an urgent need to move away from an episodic view of engagement focused on the preimplementation phase, to more continuous holistic attempts to engage with and respond to end-users.",2017-10,21/11/2018 10:01,14/04/2020 08:34,,1928-1957,,5,52,,Health Serv Res,,,,,,,,eng,(c) Health Research and Educational Trust.,,,,,,PMID: 27714800 PMCID: PMC5583302,,,,"Humans; Communication; *Attitude of Health Personnel; Leadership; England; Inservice Training; User-Computer Interface; Decision Support Systems, Clinical/*organization & administration; Medical Order Entry Systems/*organization & administration; *Hospital Administration; 00; *Health information technology; *adoption; *engagement; *implementation; Consumer Behavior; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, G4KEJK4D,journalArticle,2016,"Manley, Kim; Martin, Anne; Jackson, Carolyn; Wright, Toni",Using systems thinking to identify workforce enablers for a whole systems approach to urgent and emergency care delivery: a multiple case study.,BMC health services research,,1472-6963 1472-6963,10.1186/s12913-016-1616-y,,"BACKGROUND: Overcrowding in emergency departments is a global issue, which places pressure on the shrinking workforce and threatens the future of high quality, safe and effective care. Healthcare reforms aimed at tackling this crisis have focused primarily on structural changes, which alone do not deliver anticipated improvements in quality and performance. The purpose of this study was to identify workforce enablers for achieving whole systems urgent and emergency care delivery. METHODS: A multiple case study design framed around systems thinking was conducted in South East England across one Trust consisting of five hospitals, one community healthcare trust and one ambulance trust. Data sources included 14 clinical settings where upstream or downstream pinch points are likely to occur including discharge planning and rapid response teams; ten regional stakeholder events (n = 102); a qualitative survey (n = 48); and a review of literature and analysis of policy documents including care pathways and protocols. RESULTS: The key workforce enablers for whole systems urgent and emergency care delivery identified were: clinical systems leadership, a single integrated career and competence framework and skilled facilitation of work based learning. CONCLUSIONS: In this study, participants agreed that whole systems urgent and emergency care allows for the design and implementation of care delivery models that meet complexity of population healthcare needs, reduce duplication and waste and improve healthcare outcomes and patients' experiences. For this to be achieved emphasis needs to be placed on holistic changes in structures, processes and patterns of the urgent and emergency care system. Often overlooked, patterns that drive the thinking and behavior in the workplace directly impact on staff recruitment and retention and the overall effectiveness of the organization. These also need to be attended to for transformational change to be achieved and sustained. Research to refine and validate a single integrated career and competence framework and to develop standards for an integrated approach to workplace facilitation to grow the capacity of facilitators that can use the workplace as a resource for learning is needed.",09/08/2016,21/11/2018 10:01,14/04/2020 08:34,,368,,a,16,,BMC Health Serv Res,,,,,,,,eng,,,,,,,PMID: 27507157 PMCID: PMC4979146,,,,"Humans; Emergency Service, Hospital/*organization & administration; *Systems Analysis; Quality Improvement; Leadership; *Leadership; Data Collection; 00; *Facilitation; *Health Services Needs and Demand; *Integrated competence framework; *Multiple case study; *Urgent and emergency care; *Whole systems working; *Work based learning; *Workforce development; Emergency Medical Services/*organization & administration; England/epidemiology; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 88WLKQPU,journalArticle,2017,"Mghirbi, Oussama; LE Grusse, Philippe; Fabre, Jacques; Mandart, Elisabeth; Bord, Jean-Paul","OptiPhy, a technical-economic optimisation model for improving the management of plant protection practices in agriculture: a decision-support tool for controlling the toxicity risks related to pesticides.",Environmental science and pollution research international,,1614-7499 0944-1344,10.1007/s11356-016-6775-1,,"The health, environmental and socio-economic issues related to the massive use of plant protection products are a concern for all the stakeholders involved in the agricultural sector. These stakeholders, including farmers and territorial actors, have expressed a need for decision-support tools for the management of diffuse pollution related to plant protection practices and their impacts. To meet the needs expressed by the public authorities and the territorial actors for such decision-support tools, we have developed a technical-economic model ""OptiPhy"" for risk mitigation based on indicators of pesticide toxicity risk to applicator health (IRSA) and to the environment (IRTE), under the constraint of suitable economic outcomes. This technical-economic optimisation model is based on linear programming techniques and offers various scenarios to help the different actors in choosing plant protection products, depending on their different levels of constraints and aspirations. The health and environmental risk indicators can be broken down into sub-indicators so that management can be tailored to the context. This model for technical-economic optimisation and management of plant protection practices can analyse scenarios for the reduction of pesticide-related risks by proposing combinations of substitution PPPs, according to criteria of efficiency, economic performance and vulnerability of the natural environment. The results of the scenarios obtained on real ITKs in different cropping systems show that it is possible to reduce the PPP pressure (TFI) and reduce toxicity risks to applicator health (IRSA) and to the environment (IRTE) by up to approximately 50 %.",2017-03,21/11/2018 10:01,14/04/2020 08:34,,6951-6972,,8,24,,Environ Sci Pollut Res Int,,,,,,,,eng,,,,,,,PMID: 27164887,,,,"Humans; *Models, Theoretical; *Decision Support Techniques; Models, Economic; 00; Crop Production/economics/*methods; Crops, Agricultural/drug effects/*growth & development; Diffuse pollution; Indicators; Optimisation; Pesticides; Pesticides/analysis/*toxicity; Plant protection practices; Risk Management/economics/*methods; Technical-economic model; Toxicity risk; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LARWJERQ,journalArticle,2016,"Mercer, Stewart William; O'Brien, Rosaleen; Fitzpatrick, Bridie; Higgins, Maria; Guthrie, Bruce; Watt, Graham; Wyke, Sally",The development and optimisation of a primary care-based whole system complex intervention (CARE Plus) for patients with multimorbidity living in areas of high socioeconomic deprivation.,Chronic illness,,1745-9206 1742-3953,10.1177/1742395316644304,,"OBJECTIVES: To develop and optimise a primary care-based complex intervention (CARE Plus) to enhance the quality of life of patients with multimorbidity in the deprived areas. METHODS: Six co-design discussion groups involving 32 participants were held separately with multimorbid patients from the deprived areas, voluntary organisations, general practitioners and practice nurses working in the deprived areas. This was followed by piloting in two practices and further optimisation based on interviews with 11 general practitioners, 2 practice nurses and 6 participating multimorbid patients. RESULTS: Participants endorsed the need for longer consultations, relational continuity and a holistic approach. All felt that training and support of the health care staff was important. Most participants welcomed the idea of additional self-management support, though some practitioners were dubious about whether patients would use it. The pilot study led to changes including a revised care plan, the inclusion of mindfulness-based stress reduction techniques in the support of practitioners and patients, and the stream-lining of the written self-management support material for patients. DISCUSSION: We have co-designed and optimised an augmented primary care intervention involving a whole-system approach to enhance quality of life in multimorbid patients living in the deprived areas. CARE Plus will next be tested in a phase 2 cluster randomised controlled trial.",2016-09,21/11/2018 10:01,14/04/2020 08:34,,165-181,,3,12,,Chronic Illn,,,,,,,,eng,(c) The Author(s) 2016.,,,,,,PMID: 27068113 PMCID: PMC4995497,,,,Humans; Physician-Patient Relations; Adult; Female; Male; Middle Aged; Aged; Focus Groups; *Continuity of Patient Care; Quality of Life; Appointments and Schedules; Pilot Projects; Time Factors; *quality of life; Nurses; *Primary care; Patients; Residence Characteristics; 1; *Comorbidity; *complex intervention; *deprivation; *multimorbidity; *Poverty Areas; General Practitioners; Holistic Health; Primary Health Care/*methods/*organization & administration; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IUSC7T6N,journalArticle,2016,"Martin, Wanda; Pauly, Bernie; MacDonald, Marjorie",Situational Analysis for Complex Systems: Methodological Development in Public Health Research.,AIMS public health,,2327-8994 2327-8994,10.3934/publichealth.2016.1.94,,"Public health systems have suffered infrastructure losses worldwide. Strengthening public health systems requires not only good policies and programs, but also development of new research methodologies to support public health systems renewal. Our research team considers public health systems to be complex adaptive systems and as such new methods are necessary to generate knowledge about the process of implementing public health programs and services. Within our program of research, we have employed situational analysis as a method for studying complex adaptive systems in four distinct research studies on public health program implementation. The purpose of this paper is to demonstrate the use of situational analysis as a method for studying complex systems and highlight the need for further methodological development.",2016,21/11/2018 10:01,14/04/2020 08:34,,94-109,,1,3,,AIMS Public Health,,,,,,,,eng,,,,,,,PMID: 29546149 PMCID: PMC5690266,,,,implementation; public health; 1; methodological development: complex adaptive systems; Situational Analysis; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5UY8L5EH,journalArticle,2015,"Carey, Gemma; Malbon, Eleanor; Carey, Nicole; Joyce, Andrew; Crammond, Brad; Carey, Alan",Systems science and systems thinking for public health: a systematic review of the field.,BMJ open,,2044-6055 2044-6055,10.1136/bmjopen-2015-009002,,"OBJECTIVES: This paper reports on findings from a systematic review designed to investigate the state of systems science research in public health. The objectives were to: (1) explore how systems methodologies are being applied within public health and (2) identify fruitful areas of activity. DESIGN: A systematic review was conducted from existing literature that draws on or uses systems science (in its various forms) and relates to key public health areas of action and concern, including tobacco, alcohol, obesity and the social determinants of health. DATA ANALYSIS: 117 articles were included in the review. An inductive qualitative content analysis was used for data extraction. The following were systematically extracted from the articles: approach, methodology, transparency, strengths and weaknesses. These were then organised according to theme (ie, commonalities between studies within each category), in order to provide an overview of the state of the field as a whole. The assessment of data quality was intrinsic to the goals of the review itself, and therefore, was carried out as part of the analysis. RESULTS: 4 categories of research were identified from the review, ranging from editorial and commentary pieces to complex system dynamic modelling. Our analysis of each of these categories of research highlighted areas of potential for systems science to strengthen public health efforts, while also revealing a number of limitations in the dynamic systems modelling being carried out in public health. CONCLUSIONS: There is a great deal of interest in how the application of systems concepts and approach might aid public health. Our analysis suggests that soft systems modelling techniques are likely to be the most useful addition to public health, and align well with current debate around knowledge transfer and policy. However, the full range of systems methodologies is yet to be engaged with by public health researchers.",30/12/2015,21/11/2018 10:01,14/04/2020 08:34,,e009002,,12,5,,BMJ Open,,,,,,,,eng,Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/,,,,,,PMID: 26719314 PMCID: PMC4710830,,,,"*Systems Analysis; systems thinking; systems science; Models, Economic; Benchmarking; Evidence-Based Medicine/*standards; complexity; 1; Public Health/*methods/*standards; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IRN6IAFL,journalArticle,2015,"Rosen, Michael A.; Goeschel, Christine A.; Che, Xin-Xuan; Fawole, Joseph Oluyinka; Rees, Dianne; Curran, Rosemary; Gelinas, Lillee; Martin, Jessica N.; Kosel, Keith C.; Pronovost, Peter J.; Weaver, Sallie J.",Simulation in the Executive Suite: Lessons Learned for Building Patient Safety Leadership.,Simulation in healthcare : journal of the Society for Simulation in Healthcare,,1559-713X 1559-2332,10.1097/SIH.0000000000000122,,"INTRODUCTION: Simulation is a powerful learning tool for building individual and team competencies of frontline health care providers with demonstrable impact on performance. This article examines the impact of simulation in building strategic leadership competencies for patient safety and quality among executive leaders in health care organizations. METHODS: We designed, implemented, and evaluated a simulation as part of a larger safety leadership network meeting for executive leaders. This simulation targeted knowledge competencies of governance priority, culture of continuous improvement, and internal transparency and feedback. Eight teams of leaders in health care organizations-a total of 55 participants-participated in a 4-hour session. Each team performed collectively as a new chief executive officer (CEO) tasked with a goal of rescuing a hospital with a failing safety record. Teams worked on a modifiable simulation board reflecting the current dysfunctional organizational structure of the simulated hospital. They assessed and redesigned accountability structures based on information acquired in encounter sessions with confederates playing the role of internal staff and external consultants. RESULTS: Data were analyzed, and results are presented as qualitative themes arising from the simulation exercise, participant reaction data, and performance during the simulation. Key findings include high degrees of variability in solutions developed for the dysfunctional hospital system and generally positive learner reactions to the simulation experience. CONCLUSIONS: This study illustrates the potential value of simulation as a mechanism for learning and strategy development for executive leaders grappling with patient safety issues. Future research should explore the cognitive or functional fidelity of organizational simulations and the use of custom scenarios for strategic planning.",2015-12,21/11/2018 10:01,14/04/2020 08:35,,372-377,,6,10,,Simul Healthc,,,,,,,,eng,,,,,,,PMID: 26650703,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KZHFTZH5,journalArticle,2015,"Valk, Mark J.; Hoes, Arno W.; Mosterd, Arend; Landman, Marcel A.; Broekhuizen, Berna D. L.; Rutten, Frans H.","Rationale, design and baseline results of the Treatment Optimisation in Primary care of Heart failure in the Utrecht region (TOPHU) study: a cluster randomised controlled trial.",BMC family practice,,1471-2296 1471-2296,10.1186/s12875-015-0347-1,,"BACKGROUND: Heart failure (HF) is mainly detected and managed in primary care, but the care is considered suboptimal. We present the rationale, design and baseline results of the Treatment Optimisation in Primary care of Heart failure in the Utrecht region (TOPHU) study. In this study we assess the effect of a single training of GPs in the pharmacological management of patients with HF. METHODS/DESIGN: A cluster randomised controlled trial. Thirty primary care practices are randomly assigned to care as usual or intervention defined as a single training in the up-titration and management of HF drug therapy according to the heart failure guidelines of the European Society of Cardiology (ESC). Patients with a GP's diagnosis of HF will be re-evaluated by an expert panel of two cardiologists and a GP with expertise in HF to come to a definite diagnosis of HF according to the ESC heart failure guidelines. Those with definite HF will be analysed in this study. Drug use will be measured after six months, health status after twelve months, and heart-related hospital admissions and all-cause mortality after two years. DISCUSSION: Our cluster randomised trial will show whether a single training of GPs improves the pharmacological management of patients with HF and confers beneficial effects on health status after one year, and cardiac hospital admissions and all-cause mortality after two years of follow-up. TRIAL REGISTRATION: ClinicalTrials.gov Identifier NCT01662323.",07/10/2015,21/11/2018 10:01,14/04/2020 08:35,,130,,,16,,BMC Fam Pract,,,,,,,,eng,,,,,,,PMID: 26446696 PMCID: PMC4596366,,,,Humans; Netherlands; Treatment Outcome; Female; Male; Quality of Life; Research Design; Hospitalization/statistics & numerical data; Primary Health Care/*methods; 00; Cardiotonic Agents/therapeutic use; General Practitioners/education; Heart Failure/*drug therapy/mortality; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ZRVJTNWN,journalArticle,2015,"Sousa, Vanessa E. C.; Lopez, Karen Dunn; Febretti, Alessandro; Stifter, Janet; Yao, Yingwei; Johnson, Andrew; Wilkie, Diana J.; Keenan, Gail M.",Use of Simulation to Study Nurses' Acceptance and Nonacceptance of Clinical Decision Support Suggestions.,"Computers, informatics, nursing : CIN",,1538-9774 1538-2931,10.1097/CIN.0000000000000185,,"Our long-term goal was to ensure nurse clinical decision support works as intended before full deployment in clinical practice. As part of a broader effort, this pilot project explored factors influencing acceptance/nonacceptance of eight clinical decision support suggestions displayed in an electronic health record-based nursing plan of care software prototype. A diverse sample of 21 nurses participated in this high-fidelity clinical simulation experience and completed a questionnaire to assess reasons for accepting/not accepting the clinical decision support suggestions. Of 168 total suggestions displayed during the experiment (eight for each of the 21 nurses), 123 (73.2%) were accepted, and 45 (26.8%) were not accepted. The mode number of acceptances by nurses was seven of eight, with only two of 21 nurses accepting all. The main reason for clinical decision support acceptance was the nurse's belief that the suggestions were good for the patient (100%), with other features providing secondary reinforcement. Reasons for nonacceptance were less clear, with fewer than half of the subjects indicating low confidence in the evidence. This study provides preliminary evidence that high-quality simulation and targeted questionnaires about specific clinical decision support selections offer a cost-effective means for testing before full deployment in clinical practice.",2015-10,21/11/2018 10:01,14/04/2020 08:35,,465-472,,10,33,,Comput Inform Nurs,,,,,,,,eng,,,,,,,PMID: 26361268 PMCID: PMC4607642,,,,"Humans; Surveys and Questionnaires; Adult; Clinical Competence; Female; Male; Middle Aged; Aged; Electronic Health Records; Simulation Training/*methods; Pilot Projects; Attitude of Health Personnel; Nursing Methodology Research; 00; *Attitude to Computers; *Nursing Informatics; Decision Support Systems, Clinical/*utilization; Nursing Staff, Hospital/*psychology; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IJ5SZHG4,journalArticle,2015,"Marshall, Deborah A.; Burgos-Liz, Lina; IJzerman, Maarten J.; Crown, William; Padula, William V.; Wong, Peter K.; Pasupathy, Kalyan S.; Higashi, Mitchell K.; Osgood, Nathaniel D.",Selecting a dynamic simulation modeling method for health care delivery research-part 2: report of the ISPOR Dynamic Simulation Modeling Emerging Good Practices Task Force.,Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research,,1524-4733 1098-3015,10.1016/j.jval.2015.01.006,,"In a previous report, the ISPOR Task Force on Dynamic Simulation Modeling Applications in Health Care Delivery Research Emerging Good Practices introduced the fundamentals of dynamic simulation modeling and identified the types of health care delivery problems for which dynamic simulation modeling can be used more effectively than other modeling methods. The hierarchical relationship between the health care delivery system, providers, patients, and other stakeholders exhibits a level of complexity that ought to be captured using dynamic simulation modeling methods. As a tool to help researchers decide whether dynamic simulation modeling is an appropriate method for modeling the effects of an intervention on a health care system, we presented the System, Interactions, Multilevel, Understanding, Loops, Agents, Time, Emergence (SIMULATE) checklist consisting of eight elements. This report builds on the previous work, systematically comparing each of the three most commonly used dynamic simulation modeling methods-system dynamics, discrete-event simulation, and agent-based modeling. We review criteria for selecting the most suitable method depending on 1) the purpose-type of problem and research questions being investigated, 2) the object-scope of the model, and 3) the method to model the object to achieve the purpose. Finally, we provide guidance for emerging good practices for dynamic simulation modeling in the health sector, covering all aspects, from the engagement of decision makers in the model design through model maintenance and upkeep. We conclude by providing some recommendations about the application of these methods to add value to informed decision making, with an emphasis on stakeholder engagement, starting with the problem definition. Finally, we identify areas in which further methodological development will likely occur given the growing ""volume, velocity and variety"" and availability of ""big data"" to provide empirical evidence and techniques such as machine learning for parameter estimation in dynamic simulation models. Upon reviewing this report in addition to using the SIMULATE checklist, the readers should be able to identify whether dynamic simulation modeling methods are appropriate to address the problem at hand and to recognize the differences of these methods from those of other, more traditional modeling approaches such as Markov models and decision trees. This report provides an overview of these modeling methods and examples of health care system problems in which such methods have been useful. The primary aim of the report was to aid decisions as to whether these simulation methods are appropriate to address specific health systems problems. The report directs readers to other resources for further education on these individual modeling methods for system interventions in the emerging field of health care delivery science and implementation.",2015-03,21/11/2018 10:01,14/04/2020 08:34,,147-160,,2,18,,Value Health,,,,,,,,eng,Copyright (c) 2015. Published by Elsevier Inc.,,,,,,PMID: 25773550,,,,"Humans; methods; *Models, Theoretical; System dynamics; health care delivery; 1; Advisory Committees/trends; decision making; Delivery of Health Care/*methods/trends; dynamic simulation modeling; Health Policy/trends; Health Services Research/*methods/trends; Research Report; 320",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XAG6ZTXA,journalArticle,2015,"Okamoto, Janet",Scientific collaboration and team science: a social network analysis of the centers for population health and health disparities.,Translational behavioral medicine,,1869-6716 1613-9860,10.1007/s13142-014-0280-1,,"The past decade has seen dramatic shifts in the way that scientific research is conducted as networks, consortia, and large research centers are funded as transdisciplinary, team-based enterprises to tackle complex scientific questions. Key investigators (N = 167) involved in ten health disparities research centers completed a baseline social network and collaboration readiness survey. Collaborative ties existed primarily between investigators from the same center, with just 7 % of ties occurring across different centers. Grants and work groups were the most common types of ties between investigators, with shared presentations the most common tie across different centers. Transdisciplinary research orientation was associated with network position and reciprocity. Center directors/leaders were significantly more likely to form ties with investigators in other roles, such as statisticians and trainees. Understanding research collaboration networks can help to more effectively design and manage future team-based research, as well as pinpoint potential issues and continuous evaluation of existing efforts.",2015-03,21/11/2018 10:01,14/04/2020 08:35,,Dec-23,,1,5,,Transl Behav Med,,,,,,,,eng,,,,,,,PMID: 25729449 PMCID: PMC4332906,,,,00; Collaboration networks; Health disparities; Network analysis; Research collaboration; Scientific collaboration; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LCI87BZT,journalArticle,2015,"Saaranen, Terhi; Vaajoki, Anne; Kellomaki, Marjaana; Hyvarinen, Marja-Leena",The simulation method in learning interpersonal communication competence--experiences of masters' degree students of health sciences.,Nurse education today,,1532-2793 0260-6917,10.1016/j.nedt.2014.12.012,,"BACKGROUND: This article describes the experiences of master students of nursing science in learning interpersonal communication competence through the simulation method. The exercises reflected challenging interactive situations in the field of health care. Few studies have been published on using the simulation method in the communication education of teachers, managers, and experts in this field. OBJECTIVES: The aim of this study is to produce information which can be utilised in developing the simulation method to promote the interpersonal communication competence of master-level students of health sciences. DESIGN: This study used the qualitative, descriptive research method. SETTINGS: At the Department of Nursing Science, the University of Eastern Finland, students major in nursing science specialise in nursing leadership and management, preventive nursing science, or nurse teacher education. PARTICIPANTS: Students from all three specialties taking the Challenging Situations in Speech Communication course participated (n=47). METHODS: Essays on meaningful learning experiences collected using the critical incident technique, underwent content analysis. RESULTS: Planning of teaching, carrying out different stages of the simulation exercise, participant roles, and students' personal factors were central to learning interpersonal communication competence. CONCLUSION: Simulation is a valuable method in developing the interpersonal communication competence of students of health sciences at the masters' level. The methods used in the simulation teaching of emergency care are not necessarily applicable as such to communication education. The role of teacher is essential to supervising students' learning in simulation exercises. In the future, it is important to construct questions that help students to reflect specifically on communication.",2015-02,21/11/2018 10:01,14/04/2020 08:35,,e8-13,,2,35,,Nurse Educ Today,,,,,,,,eng,Copyright (c) 2014 Elsevier Ltd. All rights reserved.,,,,,,PMID: 25567610,,,,"Humans; Learning; Qualitative Research; Simulation Training/*methods; *Communication; Finland; *Students, Nursing; *Interpersonal Relations; Simulation; Education; Professional Competence; 00; *Education, Nursing, Graduate; Competence; Faculty, Nursing; Interpersonal communication; Nursing science; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RCR9RYQS,journalArticle,2015,"Lounsbury, David W.; Schwartz, Brian; Palma, Anton; Blank, Arthur","Simulating patterns of patient engagement, treatment adherence, and viral suppression: a system dynamics approach to evaluating HIV care management.",AIDS patient care and STDs,,1557-7449 1087-2914,10.1089/apc.2014.0276,,"System dynamics (SD) modeling belongs to the rapidly evolving, interdisciplinary field of system science research. This field adds value to more traditional health research by contributing to the design and testing of complex integrated models of change, to examine health system performance and patient outcomes. Using selected milestones in HIV care management to frame our simulation research, we created a SD model to examine three patient subgroups of women of color (WOC) represented in our multi-site cohort, classified by their health care seeking status at baseline. Asked to reflect on their circumstance 6 months prior to enrollment in the MSE cohort, 53% noted they were receiving some care (In Care, n = 341), 31% that they had been seeking care (Seeking Care, n = 201), and 16% that they were undecided about seeking care (i.e., answered that they may or may not look for care) for treatment of their HIV (May or May Not Seek Care, n = 103). Our SD model compared simulated patterns of patient retention over 24 months in relation to: (1) access to antiretroviral therapy (ART), (2) adherence to ART, and (3) viral suppression. Assessed patterns yielded insights about system capacities and constraints in the context of the SPNS initiative under evaluation.",2015-01,21/11/2018 10:01,14/04/2020 08:34,,S55-63,,,29 Suppl 1,,AIDS Patient Care STDS,,,,,,,,eng,,,,,,,PMID: 25561309 PMCID: PMC4283062,,,,"Humans; Treatment Outcome; Patient Participation; Adult; Female; *Models, Statistical; System dynamics; Continuity of Patient Care; *Medication Adherence; 1; *Viral Load; Anti-HIV Agents/*therapeutic use; HIV Infections/diagnosis/*drug therapy/virology; HIV/drug effects; Patient Care Management; 410",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, H6EYCTSG,journalArticle,2014,"Ruescas-Escolano, Esther; Orozco-Beltran, Domingo; Gaubert-Tortosa, Maria; Navarro-Palazon, Ana; Cordero-Fort, Alberto; Navarro-Perez, Jorge; Carratala-Munuera, Concepcion; Pertusa-Martinez, Salvador; Soler-Bahilo, Enrique; Brotons-Munto, Francisco; Bort-Cubero, Jose; Nunez-Martinez, Miguel A.; Bertomeu-Martinez, Vicente; Lopez-Pineda, Adriana; Gil-Guillen, Vicente F.",[The PROPRESE trial: results of a new health care organizational model in primary care for patients with chronic coronary heart disease based on a multifactorial intervention].,Atencion primaria,,1578-1275 0212-6567,10.1016/S0212-6567(14)70060-5,,"OBJECTIVE: Comparison of the results from the EUROASPIRE I to the EUROASPIRE III, in patients with coronary heart disease, shows that the prevalence of uncontrolled risk factors remains high. The aim of the study was to evaluate the effectiveness of a new multifactorial intervention in order to improve health care for chronic coronary heart disease patients in primary care. METHODS: In this randomized clinical trial with a 1-year follow-up period, we recruited patients with a diagnosis of coronary heart disease (145 for the intervention group and 1461 for the control group). An organizational intervention on the patient-professional relationship (centered on the Chronic Care Model, the Stanford Expert Patient Programme and the Kaiser Permanente model) and formative strategy for professionals were carried out. The main outcomes were smoking control, low-density lipoprotein cholesterol (LDL-C), systolic blood pressure (SBP) and diastolic blood pressure (DBP). A multivariate analysis was performed. RESULTS: The characteristics of patients were: age (68.4+/-11.8 years), male (71.6%), having diabetes mellitus (51.3%), dyslipidemia (68.5%), arterial hypertension (76.7%), non-smokers (76.1%); LDL-C < 100mg/dL (46.9%); SBP < 140mmHg (64.5%); DBP < 90 (91.2%). The multivariable analysis showed the risk of good control for intervention group to be: smoking, adjusted relative risk (aRR): 15.70 (95% confidence interval [95%CI], 4.2-58.7); P < .001; LDL-C, aRR: 2.98 (95%CI, 1.48-6.02); P < .002; SPB, aRR: 1.97 (95%CI, 1.21-3.23); P < .007, and DBP: aRR: 1.51 (95%CI, 0.65-3.50); P < .342. CONCLUSIONS: An intervention based on models for chronic patients focused in primary care and involving patients in medical decision making improves cardiovascular risk factors control (smoking,",2014-06,21/11/2018 10:01,14/04/2020 08:35,,Oct-15,,,46 Suppl 3,,Aten Primaria,,,,,,,,spa,"Copyright (c) 2014 Elsevier Espana, S.L. All rights reserved.",,,,,,PMID: 25262306,,,,"Humans; Female; Male; Risk Factors; Aged; Chronic Disease; *Models, Organizational; Primary Health Care/*organization & administration; 00; Cardiovascular diseases; Atencion primaria; Coronary Disease/*therapy; Enfermedades cardiovasculares; Health services research; Investigacion en servicios sanitarios; Prevencion secundaria; Primary care; Secondary prevention; Secondary Prevention; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NGT8I9W2,journalArticle,2014,"Ramsay, A.; Harries, A. D.; Zachariah, R.; Bissell, K.; Hinderaker, S. G.; Edginton, M.; Enarson, D. A.; Satyanarayana, S.; Kumar, A. M. V.; Hoa, N. B.; Tweya, H.; Reid, A. J.; Van den Bergh, R.; Tayler-Smith, K.; Manzi, M.; Khogali, M.; Kizito, W.; Ali, E.; Delaunois, P.; Reeder, J. C.",The Structured Operational Research and Training Initiative for public health programmes.,Public health action,,2220-8372 2220-8372,10.5588/pha.14.0011,,"In 2009, the International Union Against Tuberculosis and Lung Disease (The Union) and Medecins sans Frontieres Brussels-Luxembourg (MSF) began developing an outcome-oriented model for operational research training. In January 2013, The Union and MSF joined with the Special Programme for Research and Training in Tropical Diseases (TDR) at the World Health Organization (WHO) to form an initiative called the Structured Operational Research and Training Initiative (SORT IT). This integrates the training of public health programme staff with the conduct of operational research prioritised by their programme. SORT IT programmes consist of three one-week workshops over 9 months, with clearly-defined milestones and expected output. This paper describes the vision, objectives and structure of SORT IT programmes, including selection criteria for applicants, the research projects that can be undertaken within the time frame, the programme structure and milestones, mentorship, the monitoring and evaluation of the programmes and what happens beyond the programme in terms of further research, publications and the setting up of additional training programmes. There is a growing national and international need for operational research and related capacity building in public health. SORT IT aims to meet this need by advocating for the output-based model of operational research training for public health programme staff described here. It also aims to secure sustainable funding to expand training at a global and national level. Finally, it could act as an observatory to monitor and evaluate operational research in public health. Criteria for prospective partners wishing to join SORT IT have been drawn up.",21/06/2014,21/11/2018 10:01,14/04/2020 08:35,,79-84,,2,4,,Public Health Action,,,,,,,,eng,,,,,,,PMID: 26399203 PMCID: PMC4539036,,,,"00; capacity building; Medecins Sans Frontieres; operational research; SORT IT; The Union; WHO, TDR; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 34CSPEVG,journalArticle,2014,"Cohen, Avivit Golan; Kitai, Eliezer; David, Shaul Ben; Ziv, Amitai",Standardized patient-based simulation training as a tool to improve the management of chronic disease.,Simulation in healthcare : journal of the Society for Simulation in Healthcare,,1559-713X 1559-2332,10.1097/SIH.0000000000000009,,"INTRODUCTION: Patient education is a critical factor in the treatment of chronic disease because it reduces gaps in health care and disease management. We implemented different methods of physician training for patient education of asthma and compared the effects on patients' health. METHOD: Four interventions were administered to groups of primary care physicians in one health care maintenance organization. All physicians received a list of their patients who were classified with uncontrolled asthma. Additional educational methods were implemented as follows: no additional intervention (group 1); lectures on patient education (group 2); standardized patient-based simulation training (group 3); and lectures and standardized patient-based simulations (group 4). We compared among the intervention groups and to a control group changes in rates of patients with uncontrolled asthma at 1 and 2 years after the intervention. RESULTS: During 1 year of follow-up, rates of uncontrolled asthma decreased from 7.2% to 6.2% (by 15%), from 7.5% to 6.5% (by 13%), from 6.4% to 5.1% (by 19%), and from 6.3% to 4.6% (by 27%) in intervention groups 1 to 4, respectively (P<0.01). Rates decreased by approximately 7% more in all intervention groups at 2 years of follow-up. No decrease in rates was observed in the control group. CONCLUSIONS: An intervention for primary care physicians on educating patients with asthma to manage their disease resulted in improved patient health. The most effective intervention was the combination of lectures and standardized patient-based simulation.",2014-02,21/11/2018 10:01,14/04/2020 08:34,,40-47,,1,9,,Simul Healthc,,,,,,,,eng,,,,,,,PMID: 24492338,,,,"Humans; Surveys and Questionnaires; Female; Male; Middle Aged; *Patient Simulation; *Quality Improvement; Education, Medical, Continuing/*methods; Israel; 00; Chronic Disease/*therapy; *Patient Education as Topic; Physicians, Primary Care/*education; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9M3KKG8X,journalArticle,2012,"Noonan, Vanessa K.; Soril, Lesley; Atkins, Derek; Lewis, Rachel; Santos, Argelio; Fehlings, Michael G.; Burns, Anthony S.; Singh, Anoushka; Dvorak, Marcel F.",The application of operations research methodologies to the delivery of care model for traumatic spinal cord injury: the access to care and timing project.,Journal of neurotrauma,,1557-9042 0897-7151,10.1089/neu.2012.2317,,"The long-term impact of spinal cord injury (SCI) on the health care system imposes a need for greater efficiency in the use of resources and the management of care. The Access to Care and Timing (ACT) project was developed to model the health care delivery system in Canada for patients with traumatic SCI. Techniques from Operations Research, such as simulation modeling, were used to predict the impact of best practices and policy initiatives on outcomes related to both the system and patients. These methods have been used to solve similar problems in business and engineering and may offer a unique solution to the complexities encountered in SCI care delivery. Findings from various simulated scenarios, from the patients' point of injury to community re-integration, can be used to inform decisions on optimizing practice across the care continuum. This article describes specifically the methodology and implications of producing such simulations for the care of traumatic SCI in Canada. Future publications will report on specific practices pertaining to the access to specialized services and the timing of interventions evaluated using the ACT model. Results from this type of research will provide the evidence required to support clinical decision making, inform standards of care, and provide an opportunity to engage policymakers.",2012-09,21/11/2018 10:02,14/04/2020 08:35,,2272-2282,,13,29,,J Neurotrauma,,,,,,,,eng,,,,,,,PMID: 22800432 PMCID: PMC3430488,,,,"Humans; Canada/epidemiology; *Models, Organizational; 00; Emergency Medical Services/organization & administration/trends; Health Services Accessibility/organization & administration/trends; National Health Programs/*organization & administration/trends; Outcome Assessment (Health Care)/*methods/organization & administration; Quality of Health Care/*organization & administration/trends; Spinal Cord Injuries/economics/*mortality/*rehabilitation; Trauma Centers/organization & administration/standards/trends; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QLP5FL45,journalArticle,2012,"Aslanyan, Garry; Granger, Lucie; Edwards, Nancy; Elmslie, Kim; Fralick, Pamela; Poirier, Alain",The need for continuous systems thinking in public health in Canada.,Canadian journal of public health = Revue canadienne de sante publique,,0008-4263 0008-4263,,,,2012-04,21/11/2018 10:02,14/04/2020 08:34,,158,,2,103,,Can J Public Health,,,,,,,,eng,,,,,,,PMID: 22530542,,,,*Health Care Reform; Humans; *Public Health Administration; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, W2CNUT84,journalArticle,2012,"Patten, S. B.",The National Population Health Survey's assessment of depression risk factor associations: a simulation study assessing vulnerability to bias.,Chronic diseases and injuries in Canada,,1925-6523 1925-6515,,,"BACKGROUND: In Canada, the major source of longitudinal information on major depression epidemiology has been the National Population Health Survey (NPHS). However, the timing of NPHS interviews may raise concerns about the quality of its estimates. Specifically, the NPHS interview assesses major depressive episodes (MDE) in the year before an interview, whereas the interviews are conducted 2 years apart. The objective of this study was to determine whether this aspect of the NPHS can be expected to introduce bias into longitudinal estimates of risk factor associations. METHODS: A simulation model was used to represent the underlying epidemiology and the expected results of a study adopting the NPHS approach to assessment of MDE. The model was used to explore the extent of the resulting distortion of estimates across a range of underlying hazard ratios. RESULTS: The simulations indicated that the timing and coverage of depression interviews in the NPHS would not introduce substantial bias. The model suggested that incidence would be underestimated as a result of episodes being missed, but that this would not substantially distort estimates of association. CONCLUSION: The timing of interviews in the NPHS is not expected to cause biased relative risk estimates. NPHS estimates may, of course, be influenced by other sources of bias.",2012-03,21/11/2018 10:02,14/04/2020 08:35,,70-75,,2,32,,Chronic Dis Inj Can,,,,,,,,eng,,,,,,,PMID: 22414303,,,,"Humans; Adult; Female; Male; Middle Aged; Young Adult; Risk Factors; Aged; Child; *Computer Simulation; Adolescent; Incidence; Canada/epidemiology; Time Factors; Proportional Hazards Models; Longitudinal Studies; Bias; Depressive Disorder, Major/*epidemiology; Health Surveys/*statistics & numerical data; Risk Assessment/statistics & numerical data; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VNQNQLWS,journalArticle,2012,"Carayon, Pascale",Sociotechnical systems approach to healthcare quality and patient safety.,"Work (Reading, Mass.)",,1875-9270 1051-9815,10.3233/WOR-2012-0091-3850,,The SEIPS (Systems Engineering Initiative for Patient Safety) model of work system and patient safety is described and selected research and practical applications are presented.,2012,21/11/2018 10:02,14/04/2020 08:34,,3850-3854,,,41 Suppl 1,,Work,,,,,,,,eng,,,,,,,PMID: 22317309 PMCID: PMC3716386,,,,"Humans; *Patient Safety; *Models, Theoretical; Ergonomics; *Quality of Health Care/organization & administration; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IAQ9DYAM,journalArticle,2011,"Buckeridge, David L.; Jauvin, Christian; Okhmatovskaia, Anya; Verma, Aman D.",Simulation Analysis Platform (SnAP): a tool for evaluation of public health surveillance and disease control strategies.,AMIA ... Annual Symposium proceedings. AMIA Symposium,,1942-597X 1559-4076,,,"Increasingly, researchers use simulation to generate realistic population health data to evaluate surveillance and disease control methods. This evaluation approach is attractive because real data are often not available to describe the full range of population health trajectories that may occur. Simulation models, especially agent-based models, tend to have many parameters and it is often difficult for researchers to evaluate the effect of the multiple parameter values on model outcomes. In this paper, we describe Simulation Analysis Platform (SnAP) - a software infrastructure for automatically deploying and analyzing multiple runs of a simulation model in a manner that efficiently explores the influence of parameter uncertainty and random error on model outcomes. SnAP is designed to be efficient, scalable, extensible, and portable. We describe the design decisions taken to meet these requirements, present the design of the platform, and describe results from an example application of SnAP.",2011,21/11/2018 10:02,14/04/2020 08:34,,161-170,,,2011,,AMIA Annu Symp Proc,,,,,,,,eng,,,,,,,PMID: 22195067 PMCID: PMC3243283,,,,Humans; *Software; *Computer Simulation; Electronic Health Records; Evaluation Studies as Topic; Disease Outbreaks/*prevention & control; Public Health Surveillance/*methods; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WYMV3HGM,journalArticle,2012,"Beitsch, Leslie M.; Moran, John; Duffy, Grace",Why Don Berwick is almost right: how public health quality improvement operates within complex systems.,Journal of public health management and practice : JPHMP,,1550-5022 1078-4659,10.1097/PHH.0b013e31822ca3d3,,"Don Berwick, through his work at the Institute for Healthcare Improvement (IHI), and others have demonstrated the value of quality improvement (QI) approaches for achieving better clinical outcomes in the health care sector.1,2 Similar efforts have been under way in public health for the past decade. Several national and state initiatives have advanced the practice of quality improvement and performance management in public health and laid a strong foundation for the field. Examples include the Turning Point Performance Management Excellence Collaborative,3 the National Public Health Performance Standards Program,4 the Multi-State Learning Collaborative,5 and quality improvement programs in the Departments of Health in Florida and Washington.6,7 In addition, there are numerous successful examples in local health departments across the country.8 Each of these endeavors has contributed to the advancement of the science undergirding quality improvement. Through this learning, it has become apparent that although health care models have proven to be a source of great inspiration for public health, there is not always a perfect translation from one discipline to another. The field of QI in public health is steadily advancing. A definition specific to public health has been formulated and published.9 Studies of QI uptake demonstrate increasing capacity across the broader public health enterprise.10,11 Guidance to the field has been provided through a series of recent publications.12–19 In this brief commentary we offer our explanation for some of these differences between health care and public health QI. In addition, we provide a model that may help guide health departments as they navigate J Public Health Management Practice, 2012, 18(1), 70–73 Copyright C 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins implementation of QI in the complex public health systems in which they practice",2012-02,21/11/2018 10:02,14/04/2020 08:34,,70-73,,1,18,,J Public Health Manag Pract,,,,,,,,eng,,,,,,,PMID: 22139313,,,,Humans; *Delivery of Health Care; Quality Improvement/*organization & administration; Public Health Practice/*standards; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ZS559FDX,journalArticle,2011,"Enarson, Donald A.",Public Health Action: a new home for operational research.,Public health action,,2220-8372 2220-8372,10.5588/pha.11.0014,,,21/09/2011,21/11/2018 10:02,14/04/2020 08:34,,1,,1,1,,Public Health Action,,,,,,,,eng,,,,,,,PMID: 26392924 PMCID: PMC4547187,,,,00; ******To read; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TTYPMN2P,journalArticle,2013,"Smith, Sherrill Jeanne; Barry, Detrice G.",The use of high-fidelity simulation to teach home care nursing.,Western journal of nursing research,,1552-8456 0193-9459,10.1177/0193945911417635,,"The use of high-fidelity human patient simulation (HPS) is increasing in nursing education, yet little is known about its use in community health. This study examined an HPS home care experience to determine effects on three outcomes (student satisfaction, self-confidence, and learning). In addition, design characteristics of the simulation and demographic characteristics of students were examined for correlation with these outcomes. Senior baccalaureate students took part in the experience. Results indicated that students were very satisfied with the experience and felt it increased their confidence in providing care in the home, although learning outcomes were not high. Although no demographic characteristics were found to be correlated with outcomes, five design characteristics of a simulation were moderately correlated with the outcomes of satisfaction and self-confidence, especially support. It is recommended that nurse educators design HPS home care simulation experiences that provide student support prior to their first home care visit.",2013-03,21/11/2018 10:02,14/04/2020 08:35,,297-312,,3,35,,West J Nurs Res,,,,,,,,eng,,,,,,,PMID: 21844126,,,,"Humans; Outcome Assessment (Health Care); Adult; Female; Male; *Patient Simulation; Personal Satisfaction; Community Health Nursing/*education; Students, Nursing/psychology; *House Calls; Education, Nursing/*organization & administration; Midwestern United States; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, I3I6IKSR,journalArticle,2011,"Shinzoe, Tamon; Harada, Koji; Koizumi, Akio",[Public health for scientific study of society and health (4) Computer simulation to evaluate human exposure to environmental chemicals].,[Nihon koshu eisei zasshi] Japanese journal of public health,,0546-1766 0546-1766,,,,2011-03,21/11/2018 10:02,14/04/2020 08:35,,209-211,,3,58,,Nihon Koshu Eisei Zasshi,,,,,,,,jpn,,,,,,,PMID: 21682066,,,,Humans; Adult; Female; *Computer Simulation; Air Pollutants/*analysis; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KDLTFU8L,journalArticle,2010,"Aslanyan, Garry; Benoit, Francois; Bourgeault, Ivy Lynn; Edwards, Nancy; Hancock, Trevor; King, Arlene; Salamo, Paulina; Timmings, Carol",The inevitable health system(s) reform: an opportune time to reflect on systems thinking in public health in Canada.,Canadian journal of public health = Revue canadienne de sante publique,,0008-4263 0008-4263,,,,2010-12,21/11/2018 10:02,14/04/2020 08:34,,499,,6,101,,Can J Public Health,,,,,,,,eng,,,,,,,PMID: 21370789,,,,*Health Care Reform; Humans; Canada; Delivery of Health Care; *Public Health Administration; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, N5AZWVF2,journalArticle,2010,"Fed'ko, O. A.",[Simulation of administrative influence on a public health under conditions of changing the terminal values during the process of society transformation].,Likars'ka sprava,,1019-5297 1019-5297,,,The article is devoted to the study of interrelation between terminal values and subjective health in the context of community development and modeling of possible directions of administrative influence on a public health taking into account such interrelation. The structural model of influence of terminal values on a subjective health is presented and the assessment of possible changes of health on the population level under condition of the introduction of the proper administrative interventions is given.,2010-06,21/11/2018 10:02,14/04/2020 08:34,,100-107,,03-Apr,,,Lik Sprava,,,,,,,,ukr,,,,,,,PMID: 21265128,,,,"Humans; Socioeconomic Factors; *Models, Organizational; Models, Statistical; *Public Health Administration/standards/statistics & numerical data/trends; *Public Health/standards/statistics & numerical data/trends; *Social Values; Ukraine; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LMHJQYGU,bookSection,2008,"Zierler, Brenda K.; Wittkowsky, Ann; Peterson, Gene; Lee, Jung-Ah; Jacobson, Courtney; Glenny, Robb; Wolf, Fred; Robins, Lynne; Mitchell, Pamela; Wolpin, Seth; Payne, Tom; Hendrie, Paul; Han, Geunhye; Oh, Hyunjin",Venous Thromboembolism Safety Toolkit: A Systems Approach to Patient Safety,Advances in Patient Safety: New Directions and Alternative Approaches (Vol. 3: Performance and Tools),,,,,"The current culture in health care is focused on patient safety and on delivering quality health care across the continuum of care. However, a culture of safety by itself cannot create change within an organization. Venous thromboembolism (VTE) requires coordination of care across multiple providers supported by a system that assists in the process of delivering and tracking outcomes of care. In this paper, we describe the implementation and use of safe practice interventions for patients who have been diagnosed with VTE or are at risk for VTE. In particular, we describe the use of the evidence-based, system-supported, interactive VTE Safety Toolkit-which includes diagnostic, preventive, and therapeutic algorithms-and the On-line Provider Training Module on VTE Prophylaxis, which is a mandatory Web-based VTE educational intervention for all providers. We describe how organizations and providers can use the VTE Safety Toolkit and On-line Provider Training Module on VTE Prophylaxis to identify business process that can be changed and create a mechanism to track provider and system performance and thereby improve patient safety and accountability around VTE.",2008-08,21/11/2018 10:02,14/04/2020 08:35,,,,,,,,,,,,,Agency for Healthcare Research and Quality (US),Rockville (MD),eng,,,,,,,PMID: 21249920,,,,00; 110,,"Henriksen, Kerm; Battles, James B.; Keyes, Margaret A.; Grady, Mary L.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6SADP55B,journalArticle,2010,"Richards, Elizabeth Libby; Simpson, Vicki; Aaltonen, Pamela; Krebs, Loretta; Davis, Lynn",Public health nursing student home visit preparation: the role of simulation in increasing confidence.,Home healthcare nurse,,1539-0713 0884-741X,10.1097/NHH.0b013e3181f85e10,,The purpose of this study is to evaluate the role of simulation in preparing senior nursing students for their first home visit and to determine comfort and confidence levels of these students as they prepare for their first home visits. This exploratory study used a convenience sample of public health nursing students (n = 115). A pretest posttest design evaluated the effectiveness of the simulation using a 5-point Likert scale to detect changes in student confidence. Significant differences were noted on the majority of mean scores (p <.001) post-simulation. This approach could also be used to prepare newly hired home health care nurses and inexperienced nurses who are making the transition to home care from another aspect of nursing practice.,2010-12,21/11/2018 10:02,14/04/2020 08:35,,631-638,,10,28,,Home Healthc Nurse,,,,,,,,eng,,,,,,,PMID: 21057234,,,,"Humans; Adult; Female; Male; Students, Nursing/psychology/statistics & numerical data; *Self Efficacy; Public Health Nursing/*education; Nursing; Nurse-Patient Relations; Education; Sampling Studies; *House Calls; Professional Competence; Human; Pretest-Posttest Design; Convenience Sample; Summated Rating Scaling; Questionnaires; Evaluation Research; Surveys; Student Satisfaction; Community Health Nursing – Education; Exploratory Research; Learning Laboratories; Confidence; Comfort; Home Visits – Education; Paired T-Tests; Simulations – Evaluation; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, SF2JGPAB,journalArticle,2010,"Kunster, A. K.; Knorr, C.; Fegert, J. M.; Ziegenhain, U.",[Social network analysis of interdisciplinary cooperation and networking in early prevention and intervention. A pilot study].,"Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz",,1437-1588 1436-9990,10.1007/s00103-010-1147-3,,"Child protection can only be successfully solved by interdisciplinary cooperation and networking. The individual, heterogeneous, and complex needs of families cannot be met sufficiently by one profession alone. To guarantee efficient interdisciplinary cooperation, there should not be any gaps in the network. In addition, each actor in the network should be placed at an optimal position regarding function, responsibilities, and skills. Actors that serve as allocators, such as pediatricians or youth welfare officers, should be in key player positions within the network. Furthermore, successful child protection is preventive and starts early. Social network analysis is an adequate technique to assess network structures and to plan interventions to improve networking. In addition, it is very useful to evaluate the effectiveness of interventions like round tables. We present data from our pilot project which was part of ""Guter Start ins Kinderleben"" (""a good start into a child's life""). Exemplary network data from one community show that networking is already quite effective with a satisfactory mean density throughout the network. There is potential for improvement in cooperation, especially at the interface between the child welfare and health systems.",2010-11,21/11/2018 10:02,14/04/2020 08:34,,1134-1142,,11,53,,Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz,,,,,,,,ger,,,,,,,PMID: 20976431,,,,Pilot Projects; *Social Support; *Interdisciplinary Communication; Germany; 1; Early Intervention (Education)/*utilization; Patient Care Team/*utilization; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ZG349ZU8,journalArticle,2010,"Evans, Leigh V.; Dodge, Kelly L.",Simulation and patient safety: evaluative checklists for central venous catheter insertion.,Quality & safety in health care,,1475-3901 1475-3898,10.1136/qshc.2010.042168,,"In the advent of concerns for patient safety, simulation training is emerging as a method to train healthcare providers to perform invasive procedures such as central venous catheter (CVC) insertion while minimising harmful complications to the patient. New technologies in medical simulation have begun to shift research attention to the performance component of clinical competency. Accurate assessment of healthcare provider competence is a major priority in medical education necessitating the development of valid and reliable assessment tools. In the past year alone, nine evaluative tools, both global rating scales and procedural checklists, have been published in the research literature to evaluate the insertion of CVCs. A review of the advantages of published evaluation tools helps inform users with regard to the critical components necessary for a checklist. Ease of use, ability to be completed by a non-expert, categorical breakdown of critical actions involved in CVC insertion and the need for a comprehensive stepwise procedural checklist are discussed. The development of an ideal checklist may improve future competency-based training and performance evaluation in the clinical setting. A more thorough understanding of the status of checklists as evaluation tools in assessing performance of invasive procedures will lead to better training protocols and ultimately to improved patient safety.",2010-10,21/11/2018 10:02,14/04/2020 08:34,,i42-46,,,19 Suppl 3,,Qual Saf Health Care,,,,,,,,eng,,,,,,,PMID: 20959318,,,,"Humans; Program Evaluation; Medical Errors/prevention & control; Patient Safety; Reproducibility of Results; Education, Medical, Graduate; Computer Simulation; *Clinical Competence; *Patient Safety; Guidelines as Topic; Patient Simulation; Safety Management/*methods; *Catheterization, Central Venous; Checklist/*standards; Clinical Competence – Evaluation; Catheterization; Central Venous – Education; Checklists – Utilization; Employee Performance Appraisal – Methods; Instrument Construction; Instrument Validation; Reliability; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5SRRW6VM,journalArticle,2010,"Aggarwal, Rajesh; Mytton, Oliver T.; Derbrew, Milliard; Hananel, David; Heydenburg, Mark; Issenberg, Barry; MacAulay, Catherine; Mancini, Mary Elizabeth; Morimoto, Takeshi; Soper, Nathaniel; Ziv, Amitai; Reznick, Richard",Training and simulation for patient safety.,Quality & safety in health care,,1475-3901 1475-3898,10.1136/qshc.2009.038562,,"BACKGROUND: Simulation-based medical education enables knowledge, skills and attitudes to be acquired for all healthcare professionals in a safe, educationally orientated and efficient manner. Procedure-based skills, communication, leadership and team working can be learnt, be measured and have the potential to be used as a mode of certification to become an independent practitioner. RESULTS: Simulation-based training initially began with life-like manikins and now encompasses an entire range of systems, from synthetic models through to high fidelity simulation suites. These models can also be used for training in new technologies, for the application of existing technologies to new environments and in prototype testing. The level of simulation must be appropriate to the learners' needs and can range from focused tuition to mass trauma scenarios. The development of simulation centres is a global phenomenon which should be encouraged, although the facilities should be used within appropriate curricula that are methodologically sound and cost-effective. DISCUSSION: A review of current techniques reveals that simulation can successfully promote the competencies of medical expert, communicator and collaborator. Further work is required to develop the exact role of simulation as a training mechanism for scholarly skills, professionalism, management and health advocacy.",2010-08,21/11/2018 10:02,14/04/2020 08:34,,i34-43,,,19 Suppl 2,,Qual Saf Health Care,,,,,,,,eng,,,,,,,PMID: 20693215,,,,"Humans; Cost-Benefit Analysis; Clinical Competence; Medical Errors/prevention & control; Patient Safety; Education, Medical, Graduate; Computer Simulation; Communication; *Patient Safety; Teamwork; Health Personnel/*education; Leadership; Models, Educational; Manikins; Patient Simulation; Education; Quality Assurance, Health Care; *Educational Technology/economics/standards; Biomedical Technology; Patient Care Team/standards; Cost Benefit Analysis; Organizational Change; Health Personnel – Education; Learning Environment; Communication Skills; Simulations – Utilization; Competency-Based; Medical – History; Medical Practice – Education; Professionalism; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EKPAMAXV,journalArticle,2010,"Hamman, William R.; Beaudin-Seiler, Beth M.; Beaubien, Jeffrey M.; Gullickson, Amy M.; Orizondo-Korotko, Krystyna; Gross, Amy C.; Fuqua, Wayne; Lammers, Richard",Using in situ simulation to identify and resolve latent environmental threats to patient safety: case study involving operational changes in a labor and delivery ward.,Quality management in health care,,1550-5154 1063-8628,10.1097/QMH.0b013e3181eb1452,,"Since the publication of ""To Err Is Human"" in 1999, health care professionals have looked to high-reliability industries such as aviation for guidance on improving system safety. One of the most widely adopted aviation-derived approaches is simulation-based team training, also known as crew resource management training. In the health care domain, crew resource management training often takes place in custom-built simulation laboratories that are designed to replicate operating rooms or labor and delivery rooms. Unlike these traditional crew resource management training programs, ""in situ simulation"" occurs on actual patient care units, involves actual health care team members, and uses actual organization processes to train and assess team performance. During the past 24 months, our research team has conducted nearly 40 in situ simulations. In this article, we present the results from 1 such simulation: a patient who experienced a difficult labor that resulted in an emergency caesarian section and hysterectomy. During the simulation, a number of latent environmental threats to safety were identified. This article presents the latent threats and the steps that the hospital has taken to remedy them.",2010-09,21/11/2018 10:02,14/04/2020 08:34,,226-230,,3,19,,Qual Manag Health Care,,,,,,,,eng,,,,,,,PMID: 20588141,,,,"Humans; United States; Female; *Patient Simulation; Patient Safety; Emergencies; Pregnancy; Organizational Case Studies; *Safety Management; Medical Errors/*prevention & control; Patient Simulation; Teaching/*methods; Cesarean Section; Delivery Rooms/*organization & administration; Emergency Medical Services; Hysterectomy; Labor, Obstetric; Pregnancy Complications; Uterine Rupture; Human; Vignettes; Funding Source; Organizational Change; Case Studies; Environment – Adverse Effects; Hospital Units; Obstetric Care; Obstetric Care – Education; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Q6AMQ7VE,journalArticle,2010,"Hamman, William R.; Beaudin-Seiler, Beth M.; Beaubien, Jeffrey M.; Gullickson, Amy M.; Orizondo-Korotko, Krystyna; Gross, Amy C.; Fuqua, R. Wayne; Lammers, Richard L.",Using simulation to identify and resolve threats to patient safety.,The American journal of managed care,,1936-2692 1088-0224,,,"BACKGROUND: The simulation-based team training used in commercial aviation can provide healthcare professionals with guidance on improving patient safety. OBJECTIVE: To show how in situ simulation can identify latent environmental threats to patient safety. STUDY DESIGN: Case study. METHODS: This in situ simulation took place at a large Midwestern hospital in January 2007. It involved a patient with chest pain and hypotension that required cardiac catheterization. The simulation had 2 phases: emergency department and catheterization laboratory. Materials included a patient manikin, a high-definition camcorder, and software for annotating the video in real time. Props (eg, simulated electrocardiogram results, chest x-rays) were used. A Master Scenario Event List was used to orchestrate the entire simulation event. RESULTS: Three latent environmental threats to patient safety were identified: procedures for transporting patients between the 2 units, for managing the handoff process, and for organizing the cardiac catheterization process. These were not training issues, but were due to poorly developed or nonexistent procedures that affected the performance of all healthcare teams on those units every working day. The threats were identified by the simulation participants (along with their supervisors) during the post-simulation debriefing as being sufficiently common and dangerous to warrant further review and remedy. CONCLUSION: By conducting our simulations in the actual environment of care, using intact teams of healthcare professionals who practiced their actual technologies and work processes during the simulation, we could identify latent environmental threats to patient safety that could never be explored in an artificial laboratory environment.",01/06/2010,21/11/2018 10:02,14/04/2020 08:34,,e145-150,,6,16,,Am J Manag Care,,,,,,,,eng,,,,,,,PMID: 20536272,,,,"Humans; Safety Management/*organization & administration; Emergency Service, Hospital; *Computer Simulation; Systems Analysis; Communication; Continuity of Patient Care; Inservice Training; Software; *Manikins; Midwestern United States; Cardiac Catheterization; Personnel, Hospital/education/psychology; Risk Assessment/*organization & administration; Role Playing; Total Quality Management; Transportation of Patients; Videotape Recording; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HHLB6S8X,journalArticle,2010,"Mabry, Patricia L.; Marcus, Stephen E.; Clark, Pamela I.; Leischow, Scott J.; Mendez, David",Systems science: a revolution in public health policy research.,American journal of public health,,1541-0048 0090-0036,10.2105/AJPH.2010.198176,,"The new systems science approaches emerging in public health research are not new at all; they have a track record earned over several decades in other disciplines, such as physics, operations research, economics, engineering, and, more recently, systems biology. At their core, systems science methodologies are designed to generate models, or simplified versions, of reality. By replicating the real world in important ways—simplifying where possible while retaining the critical aspects relevant to the problem under study—we can better understand the structural complexity of real-world problems that results from the interaction of specific phenomena and their environments. Systems science approaches have been used to address wide-ranging topics such as wildfire control, overfishing, decline of ancient civilizations, climate change, and terrorism networks.",2010-07,21/11/2018 10:02,14/04/2020 08:34,,1161-1163,,7,100,,Am J Public Health,,,,,,,,eng,,,,,,,PMID: 20530757 PMCID: PMC2882409,,,,*Health Policy; Humans; United States; *Public Health Practice; Systems Integration; *Systems Theory; Empirical Research; Tobacco Industry; Tobacco Use Disorder/*prevention & control; 00; 100; ****more for intro,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5BYEXZ4E,journalArticle,2009,"Kang, Hye-Young; Ko, Su-Kyoung; Liew, Danny",Results of a Markov model analysis to assess the cost-effectiveness of statin therapy for the primary prevention of cardiovascular disease in Korea: the Korean Individual-Microsimulation Model for Cardiovascular Health Interventions.,Clinical therapeutics,,1879-114X 0149-2918,10.1016/j.clinthera.2009.12.013,,"BACKGROUND: Although hyperlipidemia is well recognized as a risk factor for cardiovascular disease (CVD), there has been no appraisal of the economic impact of statin therapy in Korea. OBJECTIVE: The aim of this model analysis was to determine the cost-effectiveness of statin therapy versus no treatment for the primary prevention of CVD over a lifetime in Korea, from a health care system perspective. METHODS: We developed the Korean Individual-Microsimulation Model for Cardiovascular Health Interventions (KIMCHI), an epidemiologic and economic Markov model of first-onset CVD in Korea in which all individuals began the simulation in the health state alive without CVD, and moved among the 4 health states (alive without CVD, alive with CVD, dead from CVD, and dead from non-CVD causes) in yearly cycles for any specified time horizon, up to 40 years. KIMCHI was populated with 372 subjects from the 2005 Korean National Health and Nutrition Examination Survey (KNHNES) who were aged > or =45 years, did not have a history of myocardial infarction or ischemic stroke, and met current Korean reimbursement criteria for treatment with lipid-lowering medications. The probability of first-onset CVD was estimated for each study participant individually, based on an Asian population-specific risk equation that relied on an individual's sex, age, serum total cholesterol, systolic blood pressure, current smoking status, diabetes mellitus status, and body mass index. Statin treatment was represented by a hybrid of atorvastatin and simvastatin (the most popular statins in Korea), the lipid-modifying effects of which were de rived from a published meta-analysis. Data regarding utilities and costs of CVD (both those covered and not covered by insurance) were derived from published local sources. RESULTS: In the base case, the estimated incremental costutility ratio was 15,134,284 Korean won (KRW) per quality-adjusted life-year (QALY) gained, and the estimated incremental cost-effectiveness ratio was 20,657,829 KRW per life-year gained (LYG) (1200 KRW approximately US $1). Based on a willingness-to-pay (WTP) threshold of 30 million KRW per QALY saved, there was a 93.7% probability that statin therapy would be cost-effective. Given a WTP threshold of 20 million KRW per QALY, there was a 53.8% probability of being cost-effective. The probabilities at WTP thresholds of 30 and 20 million KRW per LYG were 62.4% and 25.8%, respectively. CONCLUSIONS: Based on this analysis using data from the 2005 KNHNES and the KIMCHI model, statin therapy is likely to be cost-effective for the primary prevention of CVD among Koreans aged > or =45 years. The probability of being cost-effective was greater at a threshold of 30 million KRW per QALY (93.7%) than at 20 million KRW per QALY (53.8%).",2009-12,21/11/2018 10:02,14/04/2020 08:34,,2919-30; discussion 2916-2918,,12,31,,Clin Ther,,,,,,,,eng,Copyright 2009 Excerpta Medica Inc. All rights reserved.,,,,,,PMID: 20110032,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Treatment Outcome; Female; Male; Middle Aged; *Models, Economic; Aged; Risk Assessment; *Computer Simulation; Patient Selection; *Markov Chains; Sensitivity and Specificity; Age Factors; *Drug Costs; Cardiovascular Diseases/economics/etiology/mortality/*prevention & control; Hydroxymethylglutaryl-CoA Reductase Inhibitors/economics/*therapeutic use; Hyperlipidemias/complications/*drug therapy/economics/mortality; Korea/epidemiology; Preventive Health Services/*economics; Human; Data Analysis Software; Cost Benefit Analysis; Funding Source; Stroke – Prevention and Control; Coronary Disease – Prevention and Control; Coronary Disease – Drug Therapy; Demography; Hyperlipidemia – Drug Therapy; Hyperlipidemia – Prevention and Control; Korea; Statins – Therapeutic Use; Vascular Diseases – Drug Therapy; Vascular Diseases – Prevention and Control; 00; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, R6L77HWN,journalArticle,2009,"Hamman, William R.; Beaudin-Seiler, Beth M.; Beaubien, Jeffrey M.; Gullickson, Amy M.; Gross, Amy C.; Orizondo-Korotko, Krystyna; Fuqua, Wayne; Lammers, Richard",Using in situ simulation to identify and resolve latent environmental threats to patient safety: case study involving a labor and delivery ward.,Journal of patient safety,,1549-8425 1549-8417,10.1097/PTS.0b013e3181b35e6c,,"Since the publication of To Err is Human, health care professionals have looked to high-reliability industries such as commercial aviation for guidance on improving system safety. One of the most widely adopted aviation-derived approaches is simulation-based team training, also known as crew resource management (CRM) training. In the health care domain, CRM training often takes place in custom-built simulation laboratories that are designed to replicate operating rooms or labor and delivery rooms. Unlike these traditional CRM training programs, in situ simulation occurs on actual patient care units, involves actual health care team members, and uses actual organization processes to train and assess team performance. During the past 24 months, our research team has conducted nearly 40 in situ simulations. In this paper, we present the results from one such simulation: a patient who experienced a difficult labor and delivery resulting in an emergency caesarean section and a hysterectomy. During the simulation, a number of latent environmental threats to safety were identified. The following article presents not only the latent threats but also the steps that the hospital has taken to remedy them. Results from clinical simulations in operational health care settings can help identify and resolve latent environmental threats to patient safety.",2009-09,21/11/2018 10:02,14/04/2020 08:34,,184-187,,3,5,,J Patient Saf,,,,,,,,eng,,,,,,,PMID: 19927053,,,,Humans; Delivery of Health Care; Female; Patient Safety; Pregnancy; Organizational Case Studies; Surgery; Interviews as Topic; *Safety Management; Hospitals; Medical Errors/*prevention & control; Patient Simulation; Intensive Care Units; Teaching/*methods; Midwestern United States; Cesarean Section; Delivery Rooms/*organization & administration; Hysterectomy; Pregnancy Complications; Health Facilities; Technology Transfer; Funding Source; Teamwork – Education; Videorecording; Checklists; Obstetric Emergencies; Communication Barriers; Community; Fetal Monitoring; Interdepartmental Relations; Labor Complications; Neonatal; Operative – Equipment and Supplies; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CREDGVGW,journalArticle,2009,"Liew, Danny; Park, Hye-Jin; Ko, Su-Kyoung",Results of a Markov model analysis to assess the cost-effectiveness of a single tablet of fixed-dose amlodipine and atorvastatin for the primary prevention of cardiovascular disease in Korea.,Clinical therapeutics,,1879-114X 0149-2918,10.1016/j.clinthera.2009.10.015,,"BACKGROUND: In Korea, the treatment of hypertension and dyslipidemia constitutes an important strategy for the prevention of cardiovascular disease (CVD). OBJECTIVE: This study sought to investigate the cost-effectiveness (from the Korean health care system perspective) of prescribing a proprietary formulation single-tablet fixed-dose combination of amlodipine and atorvastatin (at weighted mean doses of 5 mg and 10.25 mg, respectively) to all eligible patients aged > or = 45 years for the primary prevention of CVD (ie, coronary heart disease and ischemic stroke) in Korea, compared with currently observed patterns of blood-pressure and lipid-lowering medication prescription and use. METHODS: A Markov model was developed with 4 health states: alive without CVD, alive with CVD, dead from CVD, and dead from non-CVD causes. The model population comprised 244 Koreans aged >/=45 years from the 2005 Korean National Health and Nutrition Examination Survey (KNHNES) without a history of myocardial infarction (MI) or stroke who met current criteria for both blood-pressure and lipid-lowering treatment. From a 2008 baseline, follow-up was simulated for 40 years. Cardiovascular risk was estimated for each subject individually using a multivariate, Asian population-specific equation, and updated with ongoing cycles. Decision analysis compared the effects of prescribing the fixed-dose combination to all subjects versus currently observed patterns of treatment. Data regarding the blood-pressure and lipid-lowering efficacies of combination therapy were drawn from the Respond trial. Costs of the fixed-dose combination tablet and CVD were sourced from pharmaceutical pricing lists and Korean Health Insurance Review and Assessment Services estimates, respectively. Utility values for CVD were obtained from a large Korean utility study. RESULTS: In the model, of the 244 treatment-eligible subjects, 126 (51.6%) and 13 (5.3%) were taking blood-pressure and lipid-lowering therapy, respectively. Use of single-tablet fixed-dose combination amlodipine and atorvastatin by all subjects was associated with estimated incremental cost-effectiveness ratios of 7,773,063 Korean won (KRW) per quality-adjusted life-year gained and 10,378,230 KRW per overall life-year gained (1300 KRW approximately US $1). Sensitivity and uncertainty analyses indicated these results to be robust. CONCLUSIONS: In this model, based on data from the 2005 KNHNES, hypertension and dyslipidemia were undertreated among Koreans aged > or = 45 years without a history of MI or stroke. The administration of single-tablet fixed-dose combination amlodipine and atorvastatin to all such individuals was likely to represent a cost-effective means of preventing first-onset CVD (ie, coronary heart disease and ischemic stroke) in this subgroup, compared with current patterns of treatment.",2009-10,21/11/2018 10:02,14/04/2020 08:34,,2189-203; discussion 2150-2151,,10,31,,Clin Ther,,,,,,,,eng,,,,,,,PMID: 19922890,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Female; Male; Middle Aged; Risk Factors; Aged; Markov Chains; Blood Pressure/drug effects; Models, Economic; Sensitivity and Specificity; Korea/epidemiology; Amlodipine/administration & dosage/*economics/*therapeutic use; Antihypertensive Agents/administration & dosage/*economics/*therapeutic use; Atorvastatin Calcium; Cardiovascular Diseases/epidemiology/mortality/*prevention & control; Drug Combinations; Heptanoic Acids/administration & dosage/*economics/*therapeutic use; Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & dosage/*economics/*therapeutic use; Pyrroles/administration & dosage/*economics/*therapeutic use; Confidence Intervals; Data Analysis Software; Cost Benefit Analysis; Funding Source; Multivariate Analysis; Hyperlipidemia – Drug Therapy; Korea; Amlodipine – Administration and Dosage; Atorvastatin – Administration and Dosage; Cardiovascular Diseases – Drug Therapy; Hypertension – Drug Therapy; 00; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LZZRXADU,journalArticle,2009,"Kim, H.; Kriebel, D.",Regression models for public health surveillance data: a simulation study.,Occupational and environmental medicine,,1470-7926 1351-0711,10.1136/oem.2008.042887,,"OBJECTIVES: Poisson regression is now widely used in epidemiology, but researchers do not always evaluate the potential for bias in this method when the data are overdispersed. This study used simulated data to evaluate sources of overdispersion in public health surveillance data and compare alternative statistical models for analysing such data. If count data are overdispersed, Poisson regression will not correctly estimate the variance. A model called negative binomial 2 (NB2) can correct for overdispersion, and may be preferred for analysis of count data. This paper compared the performance of Poisson and NB2 regression with simulated overdispersed injury surveillance data. METHODS: Monte Carlo simulation was used to assess the utility of the NB2 regression model as an alternative to Poisson regression for data which had several different sources of overdispersion. Simulated injury surveillance datasets were created in which an important predictor variable was omitted, as well as with an incorrect offset (denominator). The simulations evaluated the ability of Poisson regression and NB2 to correctly estimate the true determinants of injury and their confidence intervals. RESULTS: The NB2 model was effective in reducing overdispersion, but it could not reduce bias in point estimates which resulted from omitting a covariate which was a confounder, nor could it reduce bias from using an incorrect offset. One advantage of NB2 over Poisson for overdispersed data was that the confidence interval for a covariate was considerably wider with the former, providing an indication that the Poisson model did not fit well. CONCLUSION: When overdispersion is detected in a Poisson regression model, the NB2 model should be fit as an alternative. If there is no longer overdispersion, then the NB2 results may be preferred. However, it is important to remember that NB2 cannot correct for bias from omitted covariates or from using an incorrect offset.",2009-11,21/11/2018 10:02,14/04/2020 08:34,,733-739,,11,66,,Occup Environ Med,,,,,,,,eng,,,,,,,PMID: 19687020,,,,"Humans; *Models, Statistical; Epidemiologic Methods; Bias; Accidents, Occupational/statistics & numerical data; Needlestick Injuries/epidemiology; Personnel, Hospital; Population Surveillance/*methods; Human; Models; Statistical; Bias (Research); Accidents; Epidemiological Research; Health Facility; Needlestick Injuries – Epidemiology; Occupational; Personnel; Population Surveillance – Methods; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8D5XE845,journalArticle,2009,"Lebcir, Reda M.; Choudrie, Jyoti; Atun, Rifat A.; Coker, Richard J.",Using a decision support systems computer simulation model to examine HIV and tuberculosis: the Russian Federation.,International journal of electronic healthcare,,1741-8453 1741-8453,10.1504/IJEH.2009.02627,,"The aim of this paper is to describe the development and use of a computer simulation model that can be used as a Decision Support System (DSS) to tackle the critical public health issues of HIV and HIV-related tuberculosis in the Russian Federation. This country has recently witnessed an explosion of HIV infections and a worrying spread of the Multi-Drug Resistant form of Tuberculosis (MDRTB). The conclusions drawn are that a high population coverage with Highly Active Anti-Retroviral Treatment (HAART) (75% or higher), allied with high MDRTB cure rates, reduces cumulative deaths by 60%, with limited impact below this level. This research offers a simulation model that can be applied as a DSS by public health officials to inform policy making. By doing so, ways of controlling the spread of HIV and MDRTB and reduce mortality from these serious public health threats is provided.",2009,21/11/2018 10:02,14/04/2020 08:34,,14-32,,1,5,,Int J Electron Healthc,,,,,,,,eng,,,,,,,PMID: 19505866,,,,"Humans; *Computer Simulation; Russia/epidemiology; Models, Biological; Decision Support Systems, Clinical/*organization & administration; 00; AIDS-Related Opportunistic Infections/*drug therapy/mortality/transmission; Antiretroviral Therapy, Highly Active/*utilization; Antitubercular Agents/administration & dosage/*therapeutic use; Directly Observed Therapy; Tuberculosis, Multidrug-Resistant/drug therapy/mortality/transmission; Tuberculosis, Pulmonary/*drug therapy/mortality/transmission; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YAB5DA3D,journalArticle,2009,"Smith, Joan Renaud; Cole, F. Sessions",Patient safety: effective interdisciplinary teamwork through simulation and debriefing in the neonatal ICU.,Critical care nursing clinics of North America,,1558-3481 0899-5885,10.1016/j.ccell.2009.01.006,,"According to the Institute of Medicine, team training is necessary to promote a safe and high-quality patient care environment. The complexity of the neonatal ICU requires that interdisciplinary teams collaborate, coordinate, and communicate to achieve common goals and support families. The use of strategies from the aerospace, nuclear power, and national defense industries-simulation, and debriefing-equips health care providers with the knowledge, skills, and behaviors necessary to perform effectively and safely. Families are encouraged to participate in simulation and debriefing so interdisciplinary teams can learn how to approach and support families when disclosing errors and to communicate sensitive information in a safe and nonthreatening environment.",2009-06,21/11/2018 10:02,14/04/2020 08:35,,163-179,,2,21,,Crit Care Nurs Clin North Am,,,,,,,,eng,,,,,,,PMID: 19460662,,,,"Humans; Quality of Health Care; Safety Management/*organization & administration; United States/epidemiology; Communication; Infant; Teamwork; *Communication; *Interprofessional Relations; Patient Care Team/*organization & administration; *Cooperative Behavior; Health Knowledge, Attitudes, Practice; Inpatients; Attitude of Health Personnel; Inservice Training; Organizational Culture; Truth Disclosure; Collaboration; Intensive Care Units; Social Support; Continuity of Patient Care/organization & administration; Personnel, Hospital/education/psychology; Role Playing; Family/psychology; Intensive Care, Neonatal/*organization & administration/psychology; Medical Errors/prevention & control/psychology/statistics & numerical data; Professional-Family Relations; Simulations; Documentation; Patient Care Conferences; Respect; Newborn; Multidisciplinary Care Team; Health Care Errors; Neonatal; Adverse Health Care Event; Caregiver Support; Crisis Intervention; Family Centered Care; High Risk; Intensive Care; Patient Safety – In Infancy and Childhood; Sentinel Event; Shift Reports; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2K7KFNCL,journalArticle,2009,"Fattore, Giovanni; Frosini, Francesca; Salvatore, Domenico; Tozzi, Valeria",Social network analysis in primary care: the impact of interactions on prescribing behaviour.,"Health policy (Amsterdam, Netherlands)",,0168-8510 0168-8510,10.1016/j.healthpol.2009.03.005,,"OBJECTIVES: In many healthcare systems of affluent countries, general practitioners (GPs) are encouraged to work in collaborative arrangements to increase patients' accessibility and the quality of care. There are two lines of thought regarding the ways in which belonging to a network can affect GP behaviour: (1) the social capital framework posits that, through relationships, individuals acquire resources, such as information, that allow them to perform better; and (2) the social influence framework sees relationships as avenues through which individual actors influence other individuals and through which behavioural norms are developed and enforced. The objective of this study is to provide an evaluation of the effects of GP network organisation on their prescribing behaviour. METHODS: We used administrative data from a Local Health Authority (LHA) in Italy concerning GPs organisation and prescriptions. RESULTS: We found that GPs working in a collaborative arrangement have a similar prescribing behaviour while we did not find a significant relationship between the centrality of a GP and her capability to meet LHA's targets. CONCLUSIONS: Our data support the conclusion that, in the case of GP collaboration initiatives, the social influence mechanism is more relevant than the social capital mechanism.",2009-10,21/11/2018 10:02,14/04/2020 08:34,,141-148,,02-Mar,92,,Health Policy,,,,,,,,eng,,,,,,,PMID: 19356822,,,,"Humans; *Social Support; Cooperative Behavior; Italy; 1; *Drug Prescriptions; *Practice Patterns, Physicians'; General Practice/*organization & administration; National Health Programs/organization & administration; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8ISZCFU8,journalArticle,2008,"Spinello, Elio F.; Fischbach, Ronald",Using a Web-based simulation as a problem-based learning experience: perceived and actual performance of undergraduate public health students.,"Public health reports (Washington, D.C. : 1974)",,0033-3549 0033-3549,10.1177/00333549081230S211,,"OBJECTIVES: This study investigated the use of a Web-based community health simulation as a problem-based learning (PBL) experience for undergraduate students majoring in public health. The study sought to determine whether students who participated in the online simulation achieved differences in academic and attitudinal outcomes compared with students who participated in a traditional PBL exercise. METHODS: Using a nonexperimental comparative design, 21 undergraduate students enrolled in a health-behavior course were each randomly assigned to one of four workgroups. Each workgroup was randomly assigned the semester-long simulation project or the traditional PBL exercise. Survey instruments were used to measure students' attitudes toward the course, their perceptions of the learning community, and perceptions of their own cognitive learning. Content analysis of final essay exams and group reports was used to identify differences in academic outcomes and students' level of conceptual understanding of health-behavior theory. RESULTS: Findings indicated that students participating in the simulation produced higher mean final exam scores compared with students participating in the traditional PBL (p=0.03). Students in the simulation group also outperformed students in the traditional group with respect to their understanding of health-behavior theory (p=0.04). Students in the simulation group, however, rated their own level of cognitive learning lower than did students in the traditional group (p=0.03). CONCLUSIONS: By bridging time and distance constraints of the traditional classroom setting, an online simulation may be an effective PBL approach for public health students. Recommendations include further research using a larger sample to explore students' perceptions of learning when participating in simulated real-world activities. Additional research focusing on possible differences between actual and perceived learning relative to PBL methods and student workgroup dynamics is also recommended.",2008,21/11/2018 10:02,14/04/2020 08:35,,78-84,,,123 Suppl 2,,Public Health Rep,,,,,,,,eng,,,,,,,PMID: 18770921 PMCID: PMC2431099,,,,Humans; Surveys and Questionnaires; *Computer Simulation; Computer Simulation; Pilot Projects; Cognition; Disease Outbreaks; Students; Problem-Based Learning; Public Health/*education; Health Behavior; Internet; *Educational Measurement; *Internet; *Problem-Based Learning; *Social Perception; Psychological Tests; Tuberculosis/prevention & control; Human; Random Assignment; Comparative Studies; Content Analysis; Questionnaires; Student Attitudes; Public Health – Education; Allied Health; Analysis of Covariance; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RD64UMXH,journalArticle,2007,"Harris, Jenine K.; Clements, Bruce",Using social network analysis to understand Missouri's system of public health emergency planners.,"Public health reports (Washington, D.C. : 1974)",,0033-3549 0033-3549,10.1177/003335490712200410,,"OBJECTIVES: Effective response to large-scale public health threats requires well-coordinated efforts among individuals and agencies. While guidance is available to help states put emergency planning programs into place, little has been done to evaluate the human infrastructure that facilitates successful implementation of these programs. This study examined the human infrastructure of the Missouri public health emergency planning system in 2006. METHODS: The Center for Emergency Response and Terrorism (CERT) at the Missouri Department of Health and Senior Services has responsibility for planning, guiding, and funding statewide emergency response activities. Thirty-two public health emergency planners working primarily in county health departments contract with CERT to support statewide preparedness. We surveyed the planners to determine whom they communicate with, work with, seek expertise from, and exchange guidance with regarding emergency preparedness in Missouri. RESULTS: Most planners communicated regularly with planners in their region but seldom with planners outside their region. Planners also reported working with an average of 12 local entities (e.g., emergency management, hospitals/ clinics). Planners identified the following leaders in Missouri's public health emergency preparedness system: local public health emergency planners, state epidemiologists, the state vaccine and grant coordinator, regional public health emergency planners, State Emergency Management Agency area coordinators, the state Strategic National Stockpile coordinator, and Federal Bureau of Investigation Weapons of Mass Destruction coordinators. Generally, planners listed few federal-level or private-sector individuals in their emergency preparedness networks. CONCLUSIONS: While Missouri public health emergency planners maintain large and varied emergency preparedness networks, there are opportunities for strengthening existing ties and seeking additional connections.",2007-08,21/11/2018 10:02,14/04/2020 08:34,,488-498,,4,122,,Public Health Rep,,,,,,,,eng,,,,,,,PMID: 17639652 PMCID: PMC1888499,,,,Humans; Communication; *Communication; Missouri; Disaster Planning/*organization & administration; Disaster Planning; *Public Health Administration; Public Health Administration; Government Agencies/organization & administration; Interinstitutional Relations; Terrorism; Human; Government Agencies – Administration; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, I5JKK4FQ,journalArticle,2006,"Merrill, Jacqueline; Rockoff, Maxine; Bakken, Suzanne; Carley, Kathleen",Organizational network analysis: a method to model information in public health work.,AMIA ... Annual Symposium proceedings. AMIA Symposium,,1942-597X 1559-4076,,,Public health agencies are composed of complex information processing networks. The dynamic interactions of these networks affect performance in complex ways that are not easily understood. We explored how organizational network analysis can support management in public health. Managers participated in interpreting our findings and developed strategies to address the problems uncovered. The method is a means for informaticians and practitioners to build collaborative knowledge and improve public health systems using empirical evidence.,2006,21/11/2018 10:02,14/04/2020 08:34,,1030,,,,,AMIA Annu Symp Proc,,,,,,,,eng,,,,,,,PMID: 17238649 PMCID: PMC1839317,,,,"Health Services Research; *Models, Organizational; Cooperative Behavior; Organizational Culture; *Public Health Administration; Government Agencies/organization & administration; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2WYJ26IF,journalArticle,2007,"Covington, Tammie R.; Robinan Gentry, P.; Van Landingham, Cynthia B.; Andersen, Melvin E.; Kester, Janet E.; Clewell, Harvey J.",The use of Markov chain Monte Carlo uncertainty analysis to support a Public Health Goal for perchloroethylene.,Regulatory toxicology and pharmacology : RTP,,0273-2300 0273-2300,10.1016/j.yrtph.2006.06.008,,"The current Public Health Goal (PHG) for perchloroethylene (PCE) was derived using upper-bound estimates of fractional PCE metabolism in humans. These estimates were in part obtained from a published evaluation of the uncertainty and variability in human PCE metabolism conducted using a physiologically-based pharmacokinetic (PBPK) model in a Markov chain Monte Carlo (MCMC) analysis; however, the data used in that analysis were limited to post-exposure PCE blood and exhaled air concentrations from a single study. A more recent study [Volkel, W., Friedewald, M., Lederer, E., Pahler, A., Parker, J., Dekant, W., 1998. Biotransformation of perchloroethene: dose-dependent excretion of trichloroacetic acid, dichloroacetic acid, and N-acetyl-S-(trichlorovinyl)-l-cysteine in rats and humans after inhalation. Toxicol. Appl. Pharmacol. 153(1), 20-27.] provides data on blood concentrations of PCE and its major metabolite, trichloroacetic acid (TCA), and urinary excretion of TCA following exposure of human subjects to lower concentrations of PCE (10-40ppm) than in previous studies. In the present effort, a new MCMC analysis was performed that focused on data from this study along with two others [Fernandez, J., Guberan, E., Caperos, J., 1976. Experimental human exposures to tetrachloroethylene vapor and elimination in breath after inhalation. Am. Ind. Hyg. Assoc. J. 37, 143-150; Monster, A., Boersma, G., Steenweg, H., 1979. Kinetics of tetrachloroethylene in volunteers; influence of exposure concentration and work load. Int. Arch. Occup. Environ. Health 42,",2007-02,21/11/2018 10:02,14/04/2020 08:34,,Jan-18,,1,47,,Regul Toxicol Pharmacol,,,,,,,,eng,,,,,,,PMID: 16901594,,,,"Humans; Female; Male; *Public Health; *Markov Chains; Models, Statistical; Uncertainty; Dose-Response Relationship, Drug; *Monte Carlo Method; Risk Assessment/statistics & numerical data; Models, Biological; Carcinogens, Environmental/*adverse effects/pharmacokinetics; Inhalation Exposure; Tetrachloroethylene/*adverse effects/pharmacokinetics; 00; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3LHPBI4B,journalArticle,2006,"Wong, David A.",Spinal surgery and patient safety: a systems approach.,The Journal of the American Academy of Orthopaedic Surgeons,,1067-151X 1067-151X,,,"In every spinal procedure, identifying the specific patient, proper surgical site, and pathologic lesion for surgical intervention are crucial patient safety concerns. The 1999 Institute of Medicine report ""To Err is Human"" identified adverse events associated with surgery. Both the American Academy of Orthopaedic Surgeons and the North American Spine Society have had voluntary, systems-based programs in place for several years to address wrong patient, wrong procedure, and wrong site surgery. Beginning July 1, 2004, the Joint Commission on the Accreditation of Healthcare Organizations mandated that hospitals comply with the JCAHO Universal Protocol. In addition to surgical site marking, the protocol incorporates additional factors, such as calling a time out before skin incision to do a final systems check of patient identification, surgical site, records, imaging studies, equipment, and review of preoperative medication.",2006-04,21/11/2018 10:02,14/04/2020 08:35,,226-232,,4,14,,J Am Acad Orthop Surg,,,,,,,,eng,,,,,,,PMID: 16585364,,,,Humans; Outcome and Process Assessment (Health Care); Medical Errors; *Safety Management; Orthopedic Procedures/*standards; Patient Identification Systems; Spine/*surgery; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WTQNRVQ8,journalArticle,2006,"Homer, Jack B.; Hirsch, Gary B.",System dynamics modeling for public health: background and opportunities.,American journal of public health,,0090-0036 0090-0036,10.2105/AJPH.2005.062059,,"The systems modeling methodology of system dynamics is well suited to address the dynamic complexity that characterizes many public health issues. The system dynamics approach involves the development of computer simulation models that portray processes of accumulation and feedback and that may be tested systematically to find effective policies for overcoming policy resistance. System dynamics modeling of chronic disease prevention should seek to incorporate all the basic elements of a modern ecological approach, including disease outcomes, health and risk behaviors, environmental factors, and health-related resources and delivery systems. System dynamics shows promise as a means of modeling multiple interacting diseases and risks, the interaction of delivery systems and diseased populations, and matters of national and state policy.",2006-03,21/11/2018 10:02,14/04/2020 08:34,,452-458,,3,96,,Am J Public Health,,,,,,,,eng,,,,,,,PMID: 16449591 PMCID: PMC1470525,,,,Humans; United States; Chronic Disease; Computer Simulation; *Systems Theory; *Public Health Administration; Preventive Health Services/*organization & administration; 1; ******To read; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UFTH5X9X,journalArticle,2006,"Trochim, William M.; Cabrera, Derek A.; Milstein, Bobby; Gallagher, Richard S.; Leischow, Scott J.",Practical challenges of systems thinking and modeling in public health.,American journal of public health,,0090-0036 0090-0036,10.2105/AJPH.2005.066001,,"OBJECTIVES: Awareness of and support for systems thinking and modeling in the public health field are growing, yet there are many practical challenges to implementation. We sought to identify and describe these challenges from the perspectives of practicing public health professionals. METHODS: A systems-based methodology, concept mapping, was used in a study of 133 participants from 2 systems-based public health initiatives (the Initiative for the Study and Implementation of Systems and the Syndemics Prevention Network). This method identified 100 key challenges to implementation of systems thinking and modeling in public health work. RESULTS: The project resulted in a map identifying 8 categories of challenges and the dynamic interactions among them. CONCLUSIONS: Implementation by public health professionals of the 8 simple rules we derived from the clusters in the map identified here will help to address challenges and improve the organization of systems that protect the public's health.",2006-03,21/11/2018 10:02,14/04/2020 08:35,,538-546,,3,96,,Am J Public Health,,,,,,,,eng,,,,,,,PMID: 16449581 PMCID: PMC1470516,,,,"Humans; Quality of Health Care; *Models, Organizational; Public Health; *Public Health Practice; Attitude of Health Personnel; Systems Theory; *Systems Theory; Planning Techniques; *Public Health Administration; Cluster Analysis; Public Health Administration; 1; Human; Models; Theoretical; Program Implementation; Funding Source; World Wide Web; Administrative Personnel; Brainstorming; Concept Mapping; Goodness of Fit Chi Square Test; Multivariate Analysis; Organizational Development; Systems Analysis – Methods; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UQRR627W,journalArticle,2006,"Green, Lawrence W.","Public health asks of systems science: to advance our evidence-based practice, can you help us get more practice-based evidence?",American journal of public health,,0090-0036 0090-0036,10.2105/AJPH.2005.066035,,"Public health asks of systems science, as it did of sociology 40 years ago, that it help us unravel the complexity of causal forces in our varied populations and the ecologically layered community and societal circumstances of public health practice. We seek a more evidence-based public health practice, but too much of our evidence comes from artificially controlled research that does not fit the realities of practice. What can we learn from our experience with sociology in the past that might guide us in drawing effectively on systems science?",2006-03,21/11/2018 10:02,14/04/2020 08:34,,406-409,,3,96,,Am J Public Health,,,,,,,,eng,,,,,,,PMID: 16449580 PMCID: PMC1470512,,,,"Humans; Health Policy; Research; Evidence-Based Medicine; Public Health; *Public Health Practice; Systems Theory; *Systems Theory; Science; Public Health Administration/*methods; Sociology, Medical/organization & administration; Models; Theoretical; Evidence-Based; Professional Practice; Interdisciplinary; Research Support; Research Priorities; Ecology; Behavioral Sciences; Chaos Theory; Epidemiology; Sociology; Theory-Practice Relationship; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KN9N4XYN,journalArticle,2006,"Leischow, Scott J.; Milstein, Bobby",Systems thinking and modeling for public health practice.,American journal of public health,,0090-0036 0090-0036,10.2105/AJPH.2005.082842,,"Many public health workers will regard this issue of the Journal, devoted to the theme of systems thinking and modeling, as a welcome affirmation that our endeavors to protect the public’s health do indeed depend on more than the sum of their parts.",2006-03,21/11/2018 10:02,14/04/2020 08:34,,403-405,,3,96,,Am J Public Health,,,,,,,,eng,,,,,,,PMID: 16449572 PMCID: PMC1470500,,,,Humans; *Public Health Practice; *Systems Theory; Public Health Administration/*methods; Information Systems; Interinstitutional Relations; 1; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NQCA7MBC,journalArticle,2005,"Williams, Warren; Lyalin, David; Wingo, Phyllis A.",Systems thinking: what business modeling can do for public health.,Journal of public health management and practice : JPHMP,,1078-4659 1078-4659,,,"Today's public health programs are complex business systems with multiple levels of collaborating federal, state, and local entities. The use of proven systems engineering modeling techniques to analyze, align, and streamline public health operations is in the beginning stages. The authors review the initial business modeling efforts in immunization and cancer registries and present a case to broadly apply business modeling approaches to analyze and improve public health processes.",2005-12,21/11/2018 10:02,14/04/2020 08:35,,550-553,,6,11,,J Public Health Manag Pract,,,,,,,,eng,,,,,,,PMID: 16224291,,,,"United States; *Models, Organizational; Registries; Systems Theory; *Public Health Administration; Public Health Administration; 1; Informatics; Organizational Development; Business; Disease; Immunization Programs; Information Technology; Programming Languages; Systems Development; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6K6FYGIG,journalArticle,2005,"Salas, Eduardo; Wilson, Katherine A.; Burke, C. Shawn; Priest, Heather A.",Using simulation-based training to improve patient safety: what does it take?,Joint Commission journal on quality and patient safety,,1553-7250 1553-7250,,,"BACKGROUND: Through simulations health care workers can learn by practicing skills taught and experiencing mistakes before interacting with an actual patient. A number of areas within the health care industry are currently using simulation-based training to help individuals and teams improve patient safety. WHAT IS SIMULATION-BASED TRAINING? The key components of simulation-based training are as follows: performance history/skill inventory, tasks/competencies, training objectives, events/exercises, measures/metrics, performance diagnosis, and feedback and debrief. WHAT DOES IT TAKE FOR SIMULATION-BASED TRAINING TO BE EFFECTIVE? To be effective, simulation-based training must be implemented appropriately. The guidelines are as follows: understand the training needs and requirements; instructional features, such as performance measurement and feedback, must be embedded within the simulation; craft scenarios based on guidance from the learning outcomes; create opportunities for assessing and diagnosing individual and/or team performance within the simulation; guide the learning; focus on cognitive/psychological simulation fidelity; form a mutual partnership between subject matter experts and learning experts; and ensure that the training program worked. CONCLUSION: The health care community can gain significantly from using simulation-based training to reduce errors and improve patient safety when it is designed and delivered appropriately.",2005-07,21/11/2018 10:02,14/04/2020 08:35,,363-371,,7,31,,Jt Comm J Qual Patient Saf,,,,,,,,eng,,,,,,,PMID: 16130979,,,,Humans; Staff Development; United States; *Patient Simulation; Medical Errors/prevention & control; Health Personnel/*education; *Safety Management; Guidelines as Topic; Inservice Training/*methods; Feedback; Simulations; Patient Safety – Education; Personnel; Health Care Errors – Prevention and Control; Health Facility – Education; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, A4U9HWZC,journalArticle,2004,"Spinello, Elio; Fischbach, Ronald",Problem-based learning in public health instruction: a pilot study of an online simulation as a problem-based learning approach.,"Education for health (Abingdon, England)",,1357-6283 1357-6283,10.1080/13576280400002783,,"UNLABELLED: Although increasingly used as a modality in medical education, Problem-Based Learning (PBL) remains somewhat overlooked in the training of public health students (Pham & Blumberg, 2000). This project involved a pilot test of a web-based community simulation as a PBL platform in an undergraduate health behavior course. PURPOSE: To develop and pilot test a web-based computer simulation as an implementation of problem-based learning in an undergraduate public health behavior course. METHOD: Using a web-based simulation platform, a virtual community was designed in which the effects of a mock infectious disease outbreak could be studied and various interventions could be tested. Upon completion of the semester course, 14 undergraduate public health education students completed a survey and participated in a focus group to determine issues related to the simulation. Research focused on whether the simulation was perceived as motivating and which aspects were found to be confusing, ineffective or unrealistic. FINDINGS: Results of the study suggested that a PBL experience based on a community simulation may be effective in providing a motivating and interesting PBL tool for instructing undergraduate public health students. A majority of students agreed that the experience was more motivating and interesting than a more traditional assignment. Design recommendations include an emphasis on incorporating a rich multimedia background, realistic communication and project management tools and the capability for students to submit formatted documents. Further study of attitudinal differences and attainment of learning objectives is recommended between students participating in the simulation experience and those engaging in a traditional assignment.",2004-11,21/11/2018 10:02,14/04/2020 08:35,,365-373,,3,17,,Educ Health (Abingdon),,,,,,,,eng,,,,,,,PMID: 15848824,,,,Humans; Adult; Pilot Projects; Problem-Based Learning; Public Health/*education; Internet; California; *Problem-Based Learning; Analysis of Variance; Computer-Assisted Instruction/*methods; Human; Scales; Pilot Studies; Clinical Trials; Public Health – Education; Computer Assisted Instruction; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JPB22Z9I,journalArticle,2005,"Long, Rebecca E.",Using simulation to teach resuscitation: an important patient safety tool.,Critical care nursing clinics of North America,,0899-5885 0899-5885,10.1016/j.ccell.2004.09.001,,"Learning resuscitation scenarios using high-fidelity simulation can have a positive impact on real-life learning for health care professionals. Simulation sessions encourage knowledge acquisition and critical thinking for nursing students, experienced nurses, nurse anesthetists, physicians, and respiratory therapists. A novice to expert theoretical perspective can be accomplished without anxiety over scenario outcome. Results of educational endeavors support simulation use, but continued research is needed to substantiate learner outcome and technologic value.",2005-03,21/11/2018 10:02,14/04/2020 08:34,,"1-8, ix",,1,17,,Crit Care Nurs Clin North Am,,,,,,,,eng,,,,,,,PMID: 15749395,,,,"Humans; Forecasting; *Patient Simulation; Curriculum; Program Development; Computer Simulation; Resuscitation; Safety Management/*methods; Nursing; Education; Teaching/*methods; *Manikins; User-Computer Interface; Professional Competence; Clinical Competence/standards; Computer-Assisted Instruction/methods/trends; Education, Nursing/*methods/trends; Needs Assessment; Resuscitation/*education; Outcomes of Education; Teaching Methods; Models; Cost Benefit Analysis; Clinical; Skill Acquisition; Anatomic; Multidisciplinary Care Team; Simulations – Utilization; Benner's Professional Advancement Model; Cardiopulmonary – Education; Medical-Surgical Nursing – Education; Novice Nurses; Staff Development – Methods; Student Satisfaction – Evaluation; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WRMYF9XJ,journalArticle,2004,"Judd, Fiona; Davis, Julian; Hodgins, Gene; Scopelliti, Joe; Agin, Biliana; Hulbert, Carol","Rural Integrated Primary Care Psychiatry Programme: a systems approach to education, training and service integration.",Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists,,1039-8562 1039-8562,10.1046/j.1039-8562.2003.02058.x,,"OBJECTIVE: To describe the development of a rural primary care psychiatry programme, within a stepped collaborative care model. CONCLUSION: Development of a system-wide approach to the provision of mental health services offers the opportunity to increase the proportion of people with mental health problems who receive effective treatment. In addition, it enables allocation of resources and matching of interventions to patient preference and clinical need. This is particularly important in rural areas where there is a shortage of specialist mental health services and practitioners.",2004-03,21/11/2018 10:02,14/04/2020 08:34,,42-47,,1,12,,Australas Psychiatry,,,,,,,,eng,,,,,,,PMID: 15715738,,,,"Humans; Treatment Outcome; Curriculum; Family Practice/*education; Health Knowledge, Attitudes, Practice; Job Satisfaction; Cooperative Behavior; Primary Health Care/*organization & administration; Victoria; 00; Community Health Workers/education; Delivery of Health Care, Integrated/*organization & administration; Mental Disorders/epidemiology/*therapy; Mental Health Services/organization & administration; Psychiatry/*education; Rural Health/*trends; Specialization/trends; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GPD8HG52,journalArticle,2005,"Rolka, Henry; Bracy, Dwayne; Russell, Channing; Fram, David; Ball, Robert",Using simulation to assess the sensitivity and specificity of a signal detection tool for multidimensional public health surveillance data.,Statistics in medicine,,0277-6715 0277-6715,10.1002/sim.2035,,"The objective of the work described in this paper is to develop a means for characterizing the validity of an empirical methodology for detecting signals potentially related to complicated adverse event (AE) coding terms in multidimensional public health surveillance data. The signal detection tool under evaluation is the multi-item gamma Poisson shrinkage (MGPS) estimation program. We were interested in its potential application to passive surveillance system monitoring, to screen for 'signals' of complicated adverse event coding terms (AE terms) in complex and noisy data. The research was to design and produce a flexible and user-friendly utility for probabilistically defining complicated signals in a database, iterating large numbers of applications of the MGPS detection algorithm and establishing proportions of correct detection events. We sought to establish the specificity of the MGPS by developing a random background using a gradient that ranged from rigorous (but not very relevant) to relevant (but noisy). To establish the sensitivity, signals were defined based on recognized public health issues of interest (such as the introduction of a new vaccine into the population). Methods of representing a signal included a simple pair-wise association consisting of a new vaccine and one AE term, as well as a more realistic complex of multiple AE terms comprising a 'syndrome'. A web application has been developed to create and insert signals with user-defined probabilities in multiple iterations of simulated random background data. Three forms of simulated data based on the vaccine adverse event reporting system (VAERS) cumulative spontaneous database were defined to serve as background noise against which to contrast introduced vaccine adverse event signals: (1) completely random associations between vaccines and AE terms, (2) random associations of vaccine sets and AE term sets preserving naturally observed vaccine co-occurrences and AE term co-occurrences and (3) samples from the actual VAERS data as reported. Rates of detection by the MGPS algorithm can be established for specific signal patterns at varying probabilistic intensities in a choice of random background data forms. Knowing these rates is important for determining the degree of response to an MGPS signal detection event in 'live' data.",28/02/2005,21/11/2018 10:02,14/04/2020 08:35,,551-562,,4,24,,Stat Med,,,,,,,,eng,"Published in 2005 by John Wiley & Sons, Ltd.",,,,,,PMID: 15678409,"

Symposium on Statistical Methods -Study Design and Decision-Making in Public Health, Atlanta, GA, JAN 27-29, 2003

",,,"Humans; Computer Simulation; Sensitivity and Specificity; Vaccines/adverse effects; Population Surveillance/*methods; Product Surveillance, Postmarketing/methods/standards; Statistics as Topic/*methods; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FIBNNE7L,journalArticle,2005,"Tengs, Tammy O.; Ahmad, Sajjad; Savage, Jennifer M.; Moore, Rebecca; Gage, Eric",The AMA proposal to mandate nicotine reduction in cigarettes: a simulation of the population health impacts.,Preventive medicine,,0091-7435 0091-7435,10.1016/j.ypmed.2004.05.017,,"BACKGROUND: The American Medical Association (AMA) has advocated gradually reducing the nicotine content of cigarettes to decrease smoking prevalence. Some experts have voiced concerns that smokers may ""compensate"" by smoking more cigarettes or inhaling more deeply. Further, a black market may emerge, perpetuating cigarette availability. Thus, it is unclear whether a federal mandate would result in a net increase or decrease in population health. The purpose of this research is to estimate the long-term health gains or losses that are likely to accrue to the US population if the nicotine content of cigarettes is gradually reduced to trace levels over a 6-year period. METHODS: To estimate health impacts, we created the Tobacco Policy Model, a computer simulation model. The model simulates the US population as they age and change their smoking behavior over time. Secondary data for model parameters were obtained from publicly available sources. Population health impacts were measured as the change in cumulative quality-adjusted life-years (QALYs) in the US population over 50 years. RESULTS: Following a mandate to reduce nicotine, smoking prevalence is likely to decline from 23% to 5% of the population. Accordingly, a cumulative gain of 157 million QALYs is expected over 50 years. CONCLUSIONS: Despite any mortality increases due to compensatory smoking or the emergence of a black market, implementation of the AMA proposal would likely prevent the addiction of scores of new smokers and result in important gains to the nation's health. This research should prove useful to Congress as they contemplate giving the FDA the authority to regulate tobacco.",2005-02,21/11/2018 10:02,14/04/2020 08:34,,170-180,,2,40,,Prev Med,,,,,,,,eng,,,,,,,PMID: 15533526,,,,Humans; Quality-Adjusted Life Years; United States/epidemiology; System dynamics; Sensitivity and Specificity; *Health Status Indicators; Public Policy; American Medical Association; Nicotine/*analysis; Tobacco/*chemistry; 1; Markov; 210; Hybrid model; Population health,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, A9I4QP2H,journalArticle,2003,"Fone, David; Hollinghurst, Sandra; Temple, Mark; Round, Alison; Lester, Nathan; Weightman, Alison; Roberts, Katherine; Coyle, Edward; Bevan, Gwyn; Palmer, Stephen",Systematic review of the use and value of computer simulation modelling in population health and health care delivery.,Journal of public health medicine,,0957-4832 0957-4832,,,"BACKGROUND: The objective of the review was to evaluate the extent, quality and value of computer simulation modelling in population health and health care delivery. METHODS: A narrative systematic review was carried out of world literature from 1980 to 1999, searching Medline, INSPEC, Embase, HealthSTAR, Science Citation Index, CINAHL, MathSci, INFORMS Online and SIGLE databases, and researchers in the field were contacted. Papers were included if they contained a computer simulation model of individuals in a stochastic system and the topic or setting related to population health or health service delivery. RESULTS: A total of 182 papers met the inclusion criteria. Simulation modelling has been undertaken in a wide range of health care topic areas, including hospital scheduling and organization, communicable disease, screening, costs of illness and economic evaluation. However, the quality of published papers was variable and few reported on the outcomes of implementation of models, so that the value of modelling could not be assessed. CONCLUSION: Simulation modelling is a powerful method for modelling both small and large populations to inform policy makers in the provision of health care. It has been applied to a wide variety of health care problems. Although the number of modelling papers has grown substantially over recent years, further research is required to assess the value of modelling.",2003-12,21/11/2018 10:02,14/04/2020 08:34,,325-335,,4,25,,J Public Health Med,,,,,,,,eng,,,,,,,PMID: 14747592,,,,"*Models, Statistical; *Computer Simulation; *Research Design; Costs and Cost Analysis; Mass Screening; Stochastic Processes; 1; Human; Health Care Delivery; Funding Source; Computer Simulation – Utilization; CINAHL Database; Systematic Review; Embase; Medline; Computerized Literature Searching; Databases; Interrater Reliability; Reliability and Validity; *Delivery of Health Care/economics/manpower; Communicable Disease Control; Personnel Staffing and Scheduling; ******To read; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7BDGB5YE,journalArticle,2002,"Babad, Hannah; Sanderson, Colin; Naidoo, Bhash; White, Ian; Wang, Duolao",The development of a simulation model of primary prevention strategies for coronary heart disease.,Health care management science,,1386-9620 1386-9620,,,"This paper describes the present state of development of a discrete-event micro-simulation model for coronary heart disease prevention. The model is intended to support health policy makers in assessing the impacts on health care resources of different primary prevention strategies. For each person, a set of times to disease events, conditional on the individual's risk factor profile, is sampled from a set of probability distributions that are derived from a new analysis of the Framingham cohort study on coronary heart disease. Methods used to model changes in behavioural and physiological risk factors are discussed and a description of the simulation logic is given. The model incorporates POST (Patient Oriented Simulation Technique) simulation routines.",2002-11,21/11/2018 10:02,14/04/2020 08:34,,269-274,,4,5,,Health Care Manag Sci,,,,,,,,eng,,,,,,,PMID: 12437274,,,,"Humans; Risk Factors; Computer Simulation; *Decision Support Techniques; United Kingdom; *Models, Cardiovascular; Coronary Disease/*prevention & control; Primary Prevention; 00; ******To read; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CJ5495A3,journalArticle,2002,"Rauner, Marion S.","Using simulation for AIDS policy modeling: benefits for HIV/AIDS prevention policy makers in Vienna, Austria.",Health care management science,,1386-9620 1386-9620,,,"In spite of advanced therapies and the success of additional prevention programs, the HIV/AIDS epidemic still remains a challenge. Our paper refers academics, health care managers, and policy makers to the relevance of AIDS policy simulators in better decision-making. By highlighting the types of decisions AIDS policy models can support, we demonstrate the strategic role of AIDS policy simulators for the efficient and effective planning of scarce resources to fight the epidemic. For each type of decision, we then review exemplary AIDS policy simulators that have helped policy makers make better decisions. Finally, we present the benefits of an AIDS policy simulator for HIV/AIDS prevention policy makers in Vienna, Austria.",2002-04,21/11/2018 10:02,14/04/2020 08:35,,121-134,,2,5,,Health Care Manag Sci,,,,,,,,eng,,,,,,,PMID: 11993747,,,,"*Health Policy; Humans; *Models, Statistical; Computer Simulation; Efficiency, Organizational; *Decision Support Systems, Management; *Policy Making; Acquired Immunodeficiency Syndrome/epidemiology/prevention & control; Austria/epidemiology; Health Resources/supply & distribution; HIV Infections/epidemiology/*prevention & control; 1; 999",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5E3SQCNW,journalArticle,2001,"Ragnarson Tennvall, G.; Apelqvist, J.",Prevention of diabetes-related foot ulcers and amputations: a cost-utility analysis based on Markov model simulations.,Diabetologia,,0012-186X 0012-186X,10.1007/s001250100013,,"AIMS/HYPOTHESIS: We analysed the cost-effectiveness of intensified prevention in diabetic patients with different risks for foot ulcers and lower extremity amputations. Specifically, we examined whether the additional prevention costs associated with present recommendations would be offset by reduced costs of future foot ulcers and amputations. METHODS: Markov-based 5-year cost-utility simulations of current versus optimal prevention were done for hypothetical cohorts of diabetic patients older than 24 years. The model included eight possible health states for four risk groups. A population of 1677 diabetes patients provided data on present foot ulcer prevention and general mortality. Optimal prevention was defined according to the International Consensus on the Diabetic Foot. Model assumptions, transition probabilities and other data included in the model were based on published literature. The main outcome measures were cumulative incidences of foot ulcers, amputations and deaths, costs, cost-effectiveness, and quality-adjusted life years. RESULTS: An intensified prevention strategy including patient education, foot care and footwear is cost-effective if the risk for foot ulcers and lower extremity amputations can be reduced by 25 %. This is valid for all patients with diabetes except those with no specific risk factors. CONCLUSION/INTERPRETATION: Providing all diabetic patients at risk or high risk for foot ulcers and amputations with adequate prevention would be a cost-effective or even cost-saving strategy.",2001-11,21/11/2018 10:02,14/04/2020 08:35,,2077-2087,,11,44,,Diabetologia,,,,,,,,eng,,,,,,,PMID: 11719840,,,,Humans; Cost-Benefit Analysis; Adult; Markov Chains; Sweden/epidemiology; Amputation/economics/*statistics & numerical data; Diabetic Foot/economics/epidemiology/*prevention & control/surgery; Morbidity; Shoes/economics; 1; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3GSEC58A,journalArticle,2001,"Bonet, A.; Gosalbes, V.; Fito, M.; Navarro, J.",[Rational prescribing and cost reduction in the treatment of arterial hypertension: a simulation exercise].,Gaceta sanitaria,,1578-1283 0213-9111,,,"INTRODUCTION: Cost of antihypertensive drugs in Spain raises 100.000 millions of pesetas. The utilization of new drugs more expensive than classics diuretics and beta blockers is the main reason of this cost increase.The Joint National Commission on Hypertension 6th Report supports the utilization of diuretics and beta blockers as the first choice in patients without any special condition, based in their best efficience. Other professional group don't point out any therapeutic drugs because each of them have their indication. Health authorities have implemented measures intended more to achieve savings than to improve prescriptions. There are not any studies which demonstrate that the second type of measures are more efficient than first one. AIM: To realize an economic evaluation, of a program of blood hypertension treatment taking and not taking into account the The Joint National Commission on Hypertension 6th Report. METHODS: Descriptive, prescription-indication study. Cost minimization. Health center from Valencia (Spain). Three hundred and thirteen patients were studied, randomly selected. Three strategy of cost decrease were considered: a) same prescription profile using the cheapest drugs, b) change of profile taken into account JNC-VI recommendations using the original drugs, and c) second option, but using the cheapest drugs. RESULTS: Ninety seven percent of diuretics had specific indications, 84% of beta blockers, 64.5% of IECAS, 31.6% of alfa blockers and 13% de calcium channel blockers. Diuretics were counter-indicated in 3.5% of patients, beta blockers in 10.5%, and both in 3.1%. Total cost of the unmodifed prescription was 12.412.839 pesetas, cost of the first strategy was 10.067.107, of the second 5.311.783 pesetas and of the third 1.999.094 pesetas. CONCLUSIONS: Our prescription profile don't follow JNC VI recommendations and this is not justified on indications or counterindications of diuretics and beta blockers. Following JNC VI is more efficient than looking only for the cheapest drug.",2001-08,21/11/2018 10:02,14/04/2020 08:34,,327-335,,4,15,,Gac Sanit,,,,,,,,spa,,,,,,,PMID: 11578562,,,,Humans; Cost Control; Female; Male; Aged; Retrospective Studies; Drug Utilization/*economics; Antihypertensive Agents/*economics/*therapeutic use; Drug Prescriptions/*economics/*standards; Hypertension/*drug therapy/*economics; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7UEGAASF,journalArticle,2001,"Vissers, J. M.; Van Der Bij, J. D.; Kusters, R. J.",Towards decision support for waiting lists: an operations management view.,Health care management science,,1386-9620 1386-9620,,,"This paper considers the phenomenon of waiting lists in a healthcare setting, which is characterised by limitations on the national expenditure, to explore the potentials of an operations management perspective. A reference framework for waiting list management is described, distinguishing different levels of planning in healthcare--national, regional, hospital and process--that each contributes to the existence of waiting lists through managerial decision making. In addition, different underlying mechanisms in demand and supply are distinguished, which together explain the development of waiting lists. It is our contention that within this framework a series of situation specific models should be designed to support communication and decision making. This is illustrated by the modelling of the demand for cataract treatment in a regional setting in the south-eastern part of the Netherlands. An input-output model was developed to support decisions regarding waiting lists. The model projects the demand for treatment at a regional level and makes it possible to evaluate waiting list impacts for different scenarios to meet this demand.",2001-06,21/11/2018 10:02,14/04/2020 08:35,,133-142,,2,4,,Health Care Manag Sci,,,,,,,,eng,,,,,,,PMID: 11393742,,,,"Humans; Netherlands; Communication; Models, Statistical; *Decision Support Techniques; Operations Research; Planning Techniques; 00; *Needs Assessment; *Patient Selection; *Waiting Lists; Cataract Extraction/utilization; Catchment Area (Health); Decision Making, Organizational; Elective Surgical Procedures/*utilization; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7X23XSXB,journalArticle,2000,"Papatheofanis, F. J.",Utility evaluations for Markov states of lung cancer for PET-based disease management.,The quarterly journal of nuclear medicine : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR),,1125-0135 1125-0135,,,"BACKGROUND: Utilities for the health outcomes states (Markov states) of non-small cell lung carcinoma (NSCLC) should be measured to evaluate management options for patients because patients are key participants in the process of care, and their assessment of diagnostic and therapeutic value in the options presented to them ultimately impacts their net health outcomes. This investigation sought to measure utilities for stage-dependent outcomes states of NSCLC. METHODS: Persons (n = 23) with suspected NSCLC based on physical findings and computed tomography completed a short utilities survey. Utility valuations were obtained according to severity of morbidity and varied considerably. Respondents rated these health states according to accuracy measures for 18flurodeoxyglucose (18FDG) positron emission tomography (PET) imaging and medastinoscopy. RESULTS: The results demonstrate that stage-dependent morbidity is an important consideration for patients with NSCLC and should be included in any decision analysis regarding the evaluation or treatment of NSCLC. Respondents valued the quality of information obtained from non-invasive PET and invasive mediastinoscopy comparably. The utilities obtained from this investigation are useful in clinical decision-making based on Markov processes because they provide an initial estimation of utility assessment for 18FDG-based diagnostic evaluation of lung cancer. CONCLUSIONS: Consequently, these utilities will be useful in future decision analyses that require patient preference in the assignment of the evaluation of decision options (branches).",2000-06,21/11/2018 10:02,14/04/2020 08:35,,186-190,,2,44,,Q J Nucl Med,,,,,,,,eng,,,,,,,PMID: 10967627,,,,"Humans; Health Status Indicators; Outcome Assessment (Health Care); Patient Participation; Middle Aged; Aged; Cohort Studies; Decision Support Techniques; Quality of Life; *Markov Chains; Decision Making; Sensitivity and Specificity; Neoplasm Staging; Analysis of Variance; 00; Carcinoma, Non-Small-Cell Lung/*diagnostic imaging/therapy; Fluorodeoxyglucose F18; Lung Neoplasms/*diagnostic imaging/therapy; Mediastinoscopy; Radiopharmaceuticals; Tomography, Emission-Computed/*economics; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5AXQ5IXX,journalArticle,2002,"Aquilani, R.; Boni, S.; Verdirosi, S.; Pastoris, O.; Assandri, J.; Rossi, A.; Paganini, V.; Riccardi, R.; Cajelli, A.; Pernice, M.; Verri, M.; Dossena, M.; Cobelli, F.",An organizational model to translate nutritional recommendations into routine clinical practice in secondary prevention of coronary artery disease,Preventive Medicine,,0091-7435,10.1006/pmed.2001.0958,://WOS:000173788200005,,2002,21/11/2018 10:46,14/04/2020 08:34,,138-143,,2,34,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, U36P7I9R,journalArticle,2013,"Araz, O. M.",Integrating complex system dynamics of pandemic influenza with a multi-criteria decision making model for evaluating public health strategies,Journal of Systems Science and Systems Engineering,,1004-3756,10.1007/s11518-013-5220-y,://WOS:000324820400004,"Recent developments in computational sciences and computer modeling have allowed emergency preparedness exercises to include simulation models as supporting tools. These simulation models are generally built for predicting temporal and geographic patterns of disease spread. However sole use of simulation models in exercise design falls short in terms of incorporating policy decision makers' preferences into decision-making processes. In this paper, a general framework for exercising public health preparedness plans with a decision support system is presented to integrate estimation of key epidemiological parameters with a system dynamics model of an outbreak. A multi-criteria decision making framework, an Analytical Hierarchy Process model, is then developed and integrated with the simulation model to help public health policy makers prioritize their response goals and evaluate mitigation strategies in a table-top exercise environment.",2013,21/11/2018 10:46,14/04/2020 08:34,,319-339,,3,22,,,,,,,,,,,,,,,,,,,,,System Dynamics; 1; X,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MINHURAG,journalArticle,2013,"Araz, O. M.; Jehn, M.",Improving public health emergency preparedness through enhanced decision-making environments: A simulation and survey based evaluation,Technological Forecasting and Social Change,,0040-1625,10.1016/j.techfore.2012.09.018,://WOS:000326427400010,,2013,21/11/2018 10:46,14/04/2020 08:34,,1775-1781,,9,80,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WNJIXWPE,journalArticle,2006,"Bar-Yam, Y.",Improving the effectiveness of health care and public health: A multiscale complex systems analysis,American Journal of Public Health,,0090-0036,10.2105/ajph.2005.064444,://WOS:000235691300017,"The US health care system | Yaneer Bar-Yam, PhD is struggling with a mismatch between the large, simple (low-information) financial flow and the complex (high-information) treatment of individual patients. Efforts to implement cost controls and industrial efficiency that are appropriate for repetitive tasks but not high-complexity tasks lead to poor quality of care. Multiscale complex systems analysis suggests that an important step toward relieving this structural problem is a separation of responsibility for 2 distinct types of tasks: medical care of individual patients and prevention/population health. These distinct tasks require qualitatively different organizational structures. The current use of care providers and organizations for both purposes leads to compromises in organizational process that adversely affect the ability of health care organizations to provide either individual or prevention/ population services. Thus, the overall system can be dramatically improved by establishing 2 separate but linked systems with distinct organizational forms: (a) a high-efficiency system performing large-scale repetitive tasks such as screening tests, inoculations, and generic health care, and (b) a high-complexity system treating complex medical problems of individual patients.",2006,21/11/2018 10:47,14/04/2020 08:34,,459-466,,3,96,,,,,,,,,,,,,,,,,,,,,1; 110; Complex System Analysis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7BSKFE6P,journalArticle,2010,"Barbosa, C.; Taylor, B.; Godfrey, C.; Rehm, J.; Parrott, S.; Drummond, C.",Modelling lifetime QALYs and health care costs from different drinking patterns over time: a Markov model,International Journal of Methods in Psychiatric Research,,1049-8931,10.1002/mpr.306,://WOS:000278736200004,,2010,21/11/2018 10:47,14/04/2020 08:34,,97-109,,2,19,,,,,,,,,,,,,,,,,,,,,"Humans; Adult; Male; Middle Aged; Young Adult; *Cost-Benefit Analysis; *Quality-Adjusted Life Years; Aged; Cohort Studies; Decision Support Techniques; Quality of Life; *Markov Chains; Adolescent; Aged, 80 and over; Health Care Costs/*statistics & numerical data; Time Factors; Sensitivity and Specificity; Probability; United Kingdom/epidemiology; 00; *Alcohol Drinking/drug therapy/economics/prevention & control; Alcohol-Related Disorders/economics; Drinking/*physiology; 999",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, W5EJGG9W,journalArticle,2010,"Barhak, J.; Isaman, D. J. M.; Ye, W.; Lee, D.",Chronic disease modeling and simulation software,Journal of Biomedical Informatics,,1532-0464,10.1016/j.jbi.2010.06.003,://WOS:000281927200015,"Computers allow describing the progress of a disease using computerized models. These models allow aggregating expert and clinical information to allow researchers and decision makers to forecast disease progression. To make this forecast reliable, good models and therefore good modeling tools are required. This paper will describe a new computer tool designed for chronic disease modeling. The modeling capabilities of this tool were used to model the Michigan model for diabetes. The modeling approach and its advantages such as simplicity, availability, and transparency are discussed",2010,21/11/2018 10:47,14/04/2020 08:34,,791-799,,5,43,,,,,,,,,,,,,,,,,,,,,1; Markov; 320,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PNRIH836,journalArticle,2010,"Bayer, S.; Petsoulas, C.; Cox, B.; Honeyman, A.; Barlow, J.",Facilitating stroke care planning through simulation modelling,Health Informatics Journal,,1460-4582,10.1177/1460458209361142,://WOS:000279028900005,"Stroke is a leading cause of death and long-term severe disability. A major difficulty facing stroke care provision in the UK is the lack of service integration between the many authorities, professionals and stakeholders involved in the process. The objective of this article is to describe a prototype model to support integrative planning for local stroke care services. The model maps the flow of care in the acute and community segments of the care pathway for stroke patients and allows exploring alternatives for care provision. Simulation modelling can help to develop an understanding of the systemic impact of service change and improve the design and targeting of future services.",2010,21/11/2018 10:47,14/04/2020 08:34,,129-143,,2,16,,,,,,,,,,,,,,,,,,,,,discrete event simulation; 1; 320,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, U7IRCARU,journalArticle,2017,"Ben Othman, S.; Zgaya, H.; Dotoli, M.; Hammadi, S.",An agent-based Decision Support System for resources' scheduling in Emergency Supply Chains,Control Engineering Practice,,0967-0661,10.1016/j.conengprac.2016.11.014,://WOS:000393004900003,,2017,21/11/2018 10:47,14/04/2020 08:34,,27-43,,,59,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BTJ5LG34,journalArticle,2015,"Roppolo, Mattia; Kunnen, E. Saskia; van Geert, Paul L.; Mulasso, Anna; Rabaglietti, Emanuela",A quantitative dynamic systems model of health-related quality of life among older adults.,Clinical interventions in aging,,1178-1998 1176-9092,10.2147/CIA.S91605,,"Health-related quality of life (HRQOL) is a person-centered concept. The analysis of HRQOL is highly relevant in the aged population, which is generally suffering from health decline. Starting from a conceptual dynamic systems model that describes the development of HRQOL in individuals over time, this study aims to develop and test a quantitative dynamic systems model, in order to reveal the possible dynamic trends of HRQOL among older adults. The model is tested in different ways: first, with a calibration procedure to test whether the model produces theoretically plausible results, and second, with a preliminary validation procedure using empirical data of 194 older adults. This first validation tested the prediction that given a particular starting point (first empirical data point), the model will generate dynamic trajectories that lead to the observed endpoint (second empirical data point). The analyses reveal that the quantitative model produces theoretically plausible trajectories, thus providing support for the calibration procedure. Furthermore, the analyses of validation show a good fit between empirical and simulated data. In fact, no differences were found in the comparison between empirical and simulated final data for the same subgroup of participants, whereas the comparison between different subgroups of people resulted in significant differences. These data provide an initial basis of evidence for the dynamic nature of HRQOL during the aging process. Therefore, these data may give new theoretical and applied insights into the study of HRQOL and its development with time in the aging population.",2015,13/11/2018 10:47,14/04/2020 08:34,,1755-1770,,,10,,Clin Interv Aging,,,,,,,,eng,,,,,,,PMID: 26604722 PMCID: PMC4631406,,,,"Humans; Socioeconomic Factors; Female; Male; Reproducibility of Results; Aged; *Health Status; Aged, 80 and over; Computer Simulation; *Models, Theoretical; Cognition; *Quality of Life; *Interpersonal Relations; Adaptation, Psychological; validation; 1; *Mental Health; Activities of Daily Living; dynamic systems model; nonlinear equations; older adults; simulated trajectories; 410; systems dynamic model",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LKJ22E65,journalArticle,2013,"Borycki, Elizabeth; Kushniruk, Andre; Carvalho, Christopher",A methodology for validating safety heuristics using clinical simulations: identifying and preventing possible technology-induced errors related to using health information systems.,Computational and mathematical methods in medicine,,1748-6718 1748-670X,10.1155/2013/526419,,"Internationally, health information systems (HIS) safety has emerged as a significant concern for governments. Recently, research has emerged that has documented the ability of HIS to be implicated in the harm and death of patients. Researchers have attempted to develop methods that can be used to prevent or reduce technology-induced errors. Some researchers are developing methods that can be employed prior to systems release. These methods include the development of safety heuristics and clinical simulations. In this paper, we outline our methodology for developing safety heuristics specific to identifying the features or functions of a HIS user interface design that may lead to technology-induced errors. We follow this with a description of a methodological approach to validate these heuristics using clinical simulations.",2013,13/11/2018 10:47,14/04/2020 08:34,,526419,,,2013,,Comput Math Methods Med,,,,,,,,eng,,,,,,,PMID: 23606902 PMCID: PMC3626322,,,,Humans; Medical Errors/prevention & control; Evidence-Based Practice; *User-Computer Interface; 1; *Health Information Systems; Computational Biology; Safety Management/*methods/statistics & numerical data; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, N6TKQYR4,journalArticle,2014,"Nunlee, Martin; Bones, Michelle",Addressing drug adherence using an operations management model.,Journal of the American Pharmacists Association : JAPhA,,1544-3450 1086-5802,10.1331/JAPhA.2014.13150,,"OBJECTIVE To provide a model that enables health systems and pharmacy benefit managers to provide medications reliably and test for reliability and validity in the analysis of adherence to drug therapy of chronic disease. SUMMARY The quantifiable model described here can be used in conjunction with behavioral designs of drug adherence assessments. The model identifies variables that can be reproduced and expanded across the management of chronic diseases with drug therapy. By creating a reorder point system for reordering medications, the model uses a methodology commonly seen in operations research. The design includes a safety stock of medication and current supply of medication, which increases the likelihood that patients will have a continuous supply of medications, thereby positively affecting adherence by removing barriers. CONCLUSION This method identifies an adherence model that quantifies variables related to recommendations from health care providers; it can assist health care and service delivery systems in making decisions that influence adherence based on the expected order cycle days and the expected daily quantity of medication administered. This model addresses the possession of medication as a barrier to adherence.",2014-02,13/11/2018 10:47,14/04/2020 08:35,,63-68,,1,54,,J Am Pharm Assoc (2003),,,,,,,,eng,,,,,,,PMID: 24407742,,,,Humans; *Medication Adherence; Chronic Disease/drug therapy; Delivery of Health Care/methods/*standards; Drug Storage/standards; Health Personnel/standards; Pharmaceutical Preparations/*administration & dosage/*standards; 1; ****; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, N2KI6P6H,journalArticle,2014,"Fabian, Maria Patricia; Adamkiewicz, Gary; Stout, Natasha Kay; Sandel, Megan; Levy, Jonathan Ian","A simulation model of building intervention impacts on indoor environmental quality, pediatric asthma, and costs.",The Journal of allergy and clinical immunology,,1097-6825 0091-6749,10.1016/j.jaci.2013.06.003,,"BACKGROUND: Although indoor environmental conditions can affect pediatric asthmatic patients, few studies have characterized the effect of building interventions on asthma-related outcomes. Simulation models can evaluate such complex systems but have not been applied in this context. OBJECTIVE: We sought to evaluate the impact of building interventions on indoor environmental quality and pediatric asthma health care use, and to conduct cost comparisons between intervention and health care costs and energy savings. METHODS: We applied our previously developed discrete event simulation model (DEM) to simulate the effect of environmental factors, medication compliance, seasonality, and medical history on (1) pollutant concentrations indoors and (2) asthma outcomes in low-income multifamily housing. We estimated health care use and costs at baseline and subsequent to interventions, and then compared health care costs with energy savings and intervention costs. RESULTS: Interventions, such as integrated pest management and repairing kitchen exhaust fans, led to 7% to 12% reductions in serious asthma events with 1- to 3-year payback periods. Weatherization efforts targeted solely toward tightening a building envelope led to 20% more serious asthma events, but bundling with repairing kitchen exhaust fans and eliminating indoor sources (eg, gas stoves or smokers) mitigated this effect. CONCLUSION: Our pediatric asthma model provides a tool to prioritize individual and bundled building interventions based on their effects on health and costs, highlighting the tradeoffs between weatherization, indoor air quality, and health. Our work bridges the gap between clinical and environmental health sciences by increasing physicians' understanding of the effect that home environmental changes can have on their patients' asthma.",2014-01,13/11/2018 10:47,14/04/2020 08:34,,77-84,,1,133,,J Allergy Clin Immunol,,,,,,,,eng,"Copyright (c) 2013 American Academy of Allergy, Asthma & Immunology. Published by Mosby, Inc. All rights reserved.",,,,,,PMID: 23910689 PMCID: PMC3874261,,,,"Humans; Female; Male; Child; *Models, Biological; *Computer Simulation; Child, Preschool; Costs and Cost Analysis; intervention; discrete event simulation; asthma; Emergency department; 1; ****; Air Pollutants/adverse effects; Air pollution; Air Pollution, Indoor/adverse effects; allergen; Asthma/economics/*immunology/prevention & control; DEM; Discrete event simulation model; ED; energy savings; FEV(1)%; green building; housing; indoor air; Integrated pest management; IPM; lung function; Medical Expenditure Panel Survey; MEPS; Nitrogen dioxide; NO(2); Particulate matter less than 2.5 mum in diameter; Particulate Matter/adverse effects; Percent predicted forced expiratory volume in 1 second; Pest Control; PM(2.5); 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XES53VSB,journalArticle,2015,"Ye, Bixiong; E, Xueli; Zhang, Lan",[Study on the optimization of monitoring indicators of drinking water quality during health supervision].,Wei sheng yan jiu = Journal of hygiene research,,1000-8020 1000-8020,,,"OBJECTIVE: To optimize non-regular drinking water quality indices (except Giardia and Cryptosporidium) of urban drinking water. METHODS: Several methods including drinking water quality exceed the standard, the risk of exceeding standard, the frequency of detecting concentrations below the detection limit, water quality comprehensive index evaluation method, and attribute reduction algorithm of rough set theory were applied, redundancy factor of water quality indicators were eliminated, control factors that play a leading role in drinking water safety were found. RESULTS: Optimization results showed in 62 unconventional water quality monitoring indicators of urban drinking water, 42 water quality indicators could be optimized reduction by comprehensively evaluation combined with attribute reduction of rough set. CONCLUSION: Optimization of the water quality monitoring indicators and reduction of monitoring indicators and monitoring frequency could ensure the safety of drinking water quality while lowering monitoring costs and reducing monitoring pressure of the sanitation supervision departments.",2015-01,13/11/2018 10:47,14/04/2020 08:35,,33-37,,1,44,,Wei Sheng Yan Jiu,,,,,,,,chi,,,,,,,PMID: 25958632,,,,Humans; 00; *Drinking Water; *Water Supply; Cryptosporidium; Giardia; Water Quality/*standards; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9JM96KII,journalArticle,2015,"Truijens, Sophie E. M.; Banga, Franyke R.; Fransen, Annemarie F.; Pop, Victor J. M.; van Runnard Heimel, Pieter J.; Oei, S. Guid",The Effect of Multiprofessional Simulation-Based Obstetric Team Training on Patient-Reported Quality of Care: A Pilot Study.,Simulation in healthcare : journal of the Society for Simulation in Healthcare,,1559-713X 1559-2332,10.1097/SIH.0000000000000099,,"INTRODUCTION: This study aimed to explore whether multiprofessional simulation-based obstetric team training improves patient-reported quality of care during pregnancy and childbirth. METHODS: Multiprofessional teams from a large obstetric collaborative network in the Netherlands were trained in teamwork skills using the principles of crew resource management. Patient-reported quality of care was measured with the validated Pregnancy and Childbirth Questionnaire (PCQ) at 6 weeks postpartum. Before the training, 76 postpartum women (sample I) completed the questionnaire 6 weeks postpartum. Three months after the training, another sample of 68 postpartum women (sample II) completed the questionnaire. RESULTS: In sample II (after the training), the mean (SD) score of 108.9 (10.9) on the PCQ questionnaire was significantly higher than the score of 103.5 (11.6) in sample I (before training) (t = 2.75, P = 0.007). The effect size of the increase in PCQ total score was 0.5. Moreover, the subscales ""personal treatment during pregnancy"" and ""educational information"" showed a significant increase after the team training (P < 0.001). Items with the largest increase in mean scores included communication between health care professionals, clear leadership, involvement in planning, and better provision of information. CONCLUSIONS: Despite the methodological restrictions of a pilot study, the preliminary results indicate that multiprofessional simulation-based obstetric team training seems to improve patient-reported quality of care. The possibility that this improvement relates to the training is supported by the fact that the items with the largest increase are about the principles of crew resource management, used in the training.",2015-08,13/11/2018 10:47,14/04/2020 08:35,,210-216,,4,10,,Simul Healthc,,,,,,,,eng,,,,,,,PMID: 26222503,,,,"Humans; Patient Satisfaction; Socioeconomic Factors; Adult; Clinical Competence; Female; Interprofessional Relations; Simulation Training/*methods; Communication; Pilot Projects; Patient Care Team/*organization & administration; Cooperative Behavior; 00; Delivery, Obstetric/*education; Internship and Residency/methods; Obstetrics/*education; Quality of Health Care/*statistics & numerical data; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, G544IMTS,journalArticle,2015,"Toubiana, L.; Griffon, N.","Modelling, Simulation and Social Network Data: What's New for Public Health and Epidemiology Informatics?",Yearbook of medical informatics,,2364-0502 0943-4747,10.15265/IY-2015-031,,Objectives: Summarize excellent current research in the field of Public Health and Epidemiology Informatics. Method: Synopsis of the articles selected for the IMIA Yearbook 2015. Results: Four papers from international peer-reviewed journals have been selected as best papers for the section on Public Health and Epidemiology Informatics. Conclusions: The selected articles illustrate current research regarding the impact and assessment of health IT and the latest developments in health information exchange,13/08/2015,13/11/2018 10:47,14/04/2020 08:35,,216-219,,1,10,,Yearb Med Inform,,,,,,,,eng,,,,,,,PMID: 26293870 PMCID: PMC4587051,,,,"Humans; *Models, Biological; Animals; *Social Support; *Epidemics; *Medical Informatics; epidemiology; Public health; 1; Aedes; Climate Change; health information systems; hospital information systems; Influenza, Human/epidemiology; International Medical Informatics Association; medical informatics; Public Health Informatics; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XNU86EKJ,journalArticle,2015,"Stratton, Kelly G.; Cook, Andrea J.; Jackson, Lisa A.; Nelson, Jennifer C.",Simulation study comparing exposure matching with regression adjustment in an observational safety setting with group sequential monitoring.,Statistics in medicine,,1097-0258 0277-6715,10.1002/sim.6398,,"Sequential methods are well established for randomized clinical trials (RCTs), and their use in observational settings has increased with the development of national vaccine and drug safety surveillance systems that monitor large healthcare databases. Observational safety monitoring requires that sequential testing methods be better equipped to incorporate confounder adjustment and accommodate rare adverse events. New methods designed specifically for observational surveillance include a group sequential likelihood ratio test that uses exposure matching and generalized estimating equations approach that involves regression adjustment. However, little is known about the statistical performance of these methods or how they compare to RCT methods in both observational and rare outcome settings. We conducted a simulation study to determine the type I error, power and time-to-surveillance-end of group sequential likelihood ratio test, generalized estimating equations and RCT methods that construct group sequential Lan-DeMets boundaries using data from a matched (group sequential Lan-DeMets-matching) or unmatched regression (group sequential Lan-DeMets-regression) setting. We also compared the methods using data from a multisite vaccine safety study. All methods had acceptable type I error, but regression methods were more powerful, faster at detecting true safety signals and less prone to implementation difficulties with rare events than exposure matching methods. Method performance also depended on the distribution of information and extent of confounding by site. Our results suggest that choice of sequential method, especially the confounder control strategy, is critical in rare event observational settings. These findings provide guidance for choosing methods in this context and, in particular, suggest caution when conducting exposure matching.",30/03/2015,13/11/2018 10:47,14/04/2020 08:35,,1117-1133,,7,34,,Stat Med,,,,,,,,eng,"Copyright (c) 2014 John Wiley & Sons, Ltd.",,,,,,PMID: 25510526,,,,"Humans; Computer Simulation; Models, Statistical; Regression Analysis; Biostatistics/*methods; Bias; Vaccines/adverse effects; 00; Adverse Drug Reaction Reporting Systems/statistics & numerical data; generalized estimating equations; matching; Observational Studies as Topic/*statistics & numerical data; observational study; Product Surveillance, Postmarketing/statistics & numerical data; Randomized Controlled Trials as Topic/statistics & numerical data; regression; Safety/statistics & numerical data; sequential monitoring; vaccine safety; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, AKVWISV5,journalArticle,2015,"Chuang, Sheuwen; Howley, Peter P.; Lin, Shih-Hua",Implementing systems thinking for infection prevention: The cessation of repeated scabies outbreaks in a respiratory care ward.,American journal of infection control,,1527-3296 0196-6553,10.1016/j.ajic.2015.02.002,,"BACKGROUND: Root cause analysis (RCA) is often adopted to complement epidemiologic investigation for outbreaks and infection-related adverse events in hospitals; however, RCA has been argued to have limited effectiveness in preventing such events. We describe how an innovative systems analysis approach halted repeated scabies outbreaks, and highlight the importance of systems thinking for outbreaks analysis and sustaining effective infection prevention and control. METHODS: Following RCA for a third successive outbreak of scabies over a",01/05/2015,13/11/2018 10:47,14/04/2020 08:34,,499-505,,5,43,,Am J Infect Control,,,,,,,,eng,"Copyright (c) 2015 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.",,,,,,PMID: 25798774,,,,"Humans; *Systems Analysis; *Disease Outbreaks; Hospitals; Infection Control/*methods; Cross Infection/*epidemiology/*prevention & control; Disease Transmission, Infectious/prevention & control; Health care-associated infection; Root-cause analysis; Scabies outbreak; Scabies/*epidemiology/*prevention & control; Systems thinking; Systems-oriented event analysis; Taiwan/epidemiology; 1; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2FZ46P27,journalArticle,2015,"Iakusheva, M. Iu; Astaf'eva, O. V.; Deriagina, S. E.; Sergeeva, M. B.",[Scientific rationale for basic directions of the optimization of the population health in the development of municipal environmental programs].,Gigiena i sanitariia,,0016-9900 0016-9900,,,"For the solution of ecological problems in the framework of the preparation of the municipal ecological program in the city of Verkhnyaya Pyshma (Sverdlovskaya Oblast) there was peiformed the assessment of the state of population health, the evaluation of carcinogenic and non-carcinogenic health risk from chemicals that pollute the air and drinking water Atmospheric air was established to be the main environment cause for carcinogenic and non-carcinogenic risks. The obtained results served as the basis for the development of technological, sanitary and hygienical measures of the program aimed at optimizing of the population health.",2015-02,13/11/2018 10:47,14/04/2020 08:34,,117-120,,1,94,,Gig Sanit,,,,,,,,rus,,,,,,,PMID: 26031056,,,,Humans; *Public Health; Risk Factors; Retrospective Studies; Incidence; *Local Government; *Program Evaluation; Environmental Health/*legislation & jurisprudence; Environmental Illness/epidemiology/*prevention & control; Environmental Pollutants/*adverse effects; Risk Assessment/*methods; Russia/epidemiology; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, K2JSBP4N,journalArticle,2015,"Otamendi, F. Javier; Garcia-Heredia, David","Isochrones as Indicators of the Influence of Traffic in Public Health: A Visual Simulation Application in Avila, Spain.",International journal of environmental research and public health,,1660-4601 1660-4601,10.3390/ijerph121012556,,"It is well known that excessive rescue times after traffic accidents negatively affect the health of those injured. There is a need to quantitatively measure the impact of unexpected events like ambulance availability, weather, floating population and congestion in those rescue times. A family of indicators based on isochrones is disguised and proposed to understand the risk of the whole population as the probability of not being assisted on time. Indicators of health risk for local towns are also defined. The indicators are calculated using a simulation model and visualized in web format. The framework of analysis is validated using Avila (Spain) and the problem of the optimal deployment of ambulances as a test-bench.",09/10/2015,13/11/2018 10:47,14/04/2020 08:35,,12556-12576,,10,12,,Int J Environ Res Public Health,,,,,,,,eng,,,,,,,PMID: 26473894 PMCID: PMC4626986,,,,"Humans; Public Health/*methods; Models, Theoretical; Time Factors; Risk; Spain; 00; *Accidents, Traffic/statistics & numerical data; *Rescue Work/statistics & numerical data; ambulance deployment; Ambulances/*utilization; Emergency Medical Service Communication Systems; golden hour; isochrones; small towns; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XXRFJQHU,journalArticle,2016,"Ma, Jinhui; Thabane, Lehana; Beyene, Joseph; Raina, Parminder",Power Analysis for Population-Based Longitudinal Studies Investigating Gene-Environment Interactions in Chronic Diseases: A Simulation Study.,PloS one,,1932-6203 1932-6203,10.1371/journal.pone.0149940,,"Conventional methods for sample size calculation for population-based longitudinal studies tend to overestimate the statistical power by overlooking important determinants of the required sample size, such as the measurement errors and unmeasured etiological determinants, etc. In contrast, a simulation-based sample size calculation, if designed properly, allows these determinants to be taken into account and offers flexibility in accommodating complex study design features. The Canadian Longitudinal Study on Aging (CLSA) is a Canada-wide, 20-year follow-up study of 30,000 people between the ages of 45 and 85 years, with in-depth information collected every 3 years. A simulation study, based on an illness-death model, was conducted to: (1) investigate the statistical power profile of the CLSA to detect the effect of environmental and genetic risk factors, and their interaction on age-related chronic diseases; and (2) explore the design alternatives and implementation strategies for increasing the statistical power of population-based longitudinal studies in general. The results showed that the statistical power to identify the effect of environmental and genetic risk exposures, and their interaction on a disease was boosted when: (1) the prevalence of the risk exposures increased; (2) the disease of interest is relatively common in the population; and (3) risk exposures were measured accurately. In addition, the frequency of data collection every three years in the CLSA led to a slightly lower statistical power compared to the design assuming that participants underwent health monitoring continuously. The CLSA had sufficient power to detect a small (1/=0.1) and the disease of interest was not rare (such as diabetes and dementia). The CLSA had enough power to detect a large effect of the gene-environment interaction only when both risk exposures had relatively high prevalence (0.2) and the disease of interest was very common (such as diabetes). The minimum detectable hazard ratios (MDHR) of the CLSA for the environmental and genetic risk exposures obtained from this simulation study were larger than those calculated according to the conventional sample size calculation method. For example, the MDHR for the environmental risk exposure was 1.15 according to the conventional method if the prevalence of the risk exposure was 0.1 and the disease of interest was dementia. In contrast, the MDHR was 1.61 if the same exposure was measured every 3 years with a misclassification rate of 0.1 according to this simulation study. With a given sample size, higher statistical power could be achieved by increasing the measuring frequency in participants with high risk of declining health status or changing risk exposures, and by increasing measurement accuracy of diseases and risk exposures. A properly designed simulation-based sample size calculation is superior to conventional methods when rigorous sample size calculation is necessary.",2016,13/11/2018 10:47,14/04/2020 08:34,,e0149940,,2,11,,PLoS One,,,,,,,,eng,,,,,,,PMID: 26901422 PMCID: PMC4762766,,,,"Humans; Female; Male; Middle Aged; Aged; *Computer Simulation; Aged, 80 and over; Models, Theoretical; *Chronic Disease; *Gene-Environment Interaction; Longitudinal Studies; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ZKFJXXG2,journalArticle,2016,"Williams, Cylie; Bowles, Kelly-Ann; Kiegaldie, Debra; Maloney, Stephen; Nestel, Debra; Kaplonyi, Jessica; Haines, Terry","Establishing the effectiveness, cost-effectiveness and student experience of a Simulation-based education Training program On the Prevention of Falls (STOP-Falls) among hospitalised inpatients: a protocol for a randomised controlled trial.",BMJ open,,2044-6055 2044-6055,10.1136/bmjopen-2015-010192,,"INTRODUCTION: Simulation-based education (SBE) is now commonly used across health professional disciplines to teach a range of skills. The evidence base supporting the effectiveness of this approach for improving patient health outcomes is relatively narrow, focused mainly on the development of procedural skills. However, there are other simulation approaches used to support non-procedure specific skills that are in need of further investigation. This cluster, cross-over randomised controlled trial with a concurrent economic evaluation (cost per fall prevented) trial will evaluate the effectiveness, cost-effectiveness and student experience of health professional students undertaking simulation training for the prevention of falls among hospitalised inpatients. This research will target the students within the established undergraduate student placements of Monash University medicine, nursing and allied health across Peninsula Health acute and subacute inpatient wards. METHODS AND ANALYSIS: The intervention will train the students in how to provide the Safe Recovery program, the only single intervention approach demonstrated to reduce falls in hospitals. This will involve redevelopment of the Safe Recovery program into a one-to-many participant SBE program, so that groups of students learn the communication skills and falls prevention knowledge necessary for delivery of the program. The primary outcome of this research will be patient falls across participating inpatient wards, with secondary outcomes including student satisfaction with the SBE and knowledge gain, ward-level practice change and cost of acute/rehabilitation care for each patient measured using clinical costing data. ETHICS AND DISSEMINATION: The Human Research Ethics Committees of Peninsula Health (LRR/15/PH/11) and Monash University (CF15/3523-2015001384) have approved this research. The participant information and consent forms provide information on privacy, storage of results and dissemination. Registration of this trial has been completed with the Australian and New Zealand Clinical Trials Registry: ACTRN12615000817549. This study protocol has been prepared according to the Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) checklist. TRIAL REGISTRATION NUMBER: ACTRN12615000817549; Pre-results.",02/06/2016,13/11/2018 10:47,14/04/2020 08:35,,e010192,,6,6,,BMJ Open,,,,,,,,eng,Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/,,,,,,PMID: 27256087 PMCID: PMC4893858,,,,"Humans; Cost-Benefit Analysis; Simulation Training/*methods; Australia; Research Design; *HEALTH ECONOMICS; Inpatients; Logistic Models; Students; 00; *GERIATRIC MEDICINE; *MEDICAL EDUCATION & TRAINING; Accidental Falls/*prevention & control; Education, Medical, Undergraduate; Education/*economics; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, V5WJ87IR,journalArticle,2016,"Love, Peter E. D.; Ding, Lieyun; Luo, Hanbin",Systems thinking in workplace safety and health in construction: Bridging the gap between theory and practice.,Accident; analysis and prevention,,1879-2057 0001-4575,10.1016/j.aap.2016.05.026,,,2016-08,13/11/2018 10:47,14/04/2020 08:34,,227-229,,,93,,Accid Anal Prev,,,,,,,,eng,,,,,,,PMID: 27297717,,,,"Humans; *Safety; *Systems Analysis; Health Knowledge, Attitudes, Practice; *Workplace; 00; *Construction Industry; *Occupational Health; *Thinking; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XK9PBWBQ,journalArticle,2016,"Baxley, Elizabeth G.; Lawson, Luan; Garrison, Herbert G.; Walsh, Danielle; Lazorick, Suzanne; Lake, Donna; Higginson, Jason",The Teachers of Quality Academy: A Learning Community Approach to Preparing Faculty to Teach Health Systems Science.,Academic medicine : journal of the Association of American Medical Colleges,,1938-808X 1040-2446,10.1097/ACM.0000000000001262,,"PROBLEM: Although efforts to integrate health systems science (HSS) topics, such as patient safety, quality improvement (QI), interprofessionalism, and population health, into health professions curricula are increasing, the rate of change has been slow. APPROACH: The Teachers of Quality Academy (TQA), Brody School of Medicine at East Carolina University, was established in January 2014 with the dual goal of preparing faculty to lead frontline clinical transformation while becoming proficient in the pedagogy and curriculum design necessary to prepare students in HSS competencies. The TQA included the completion of the Institute for Healthcare Improvement Open School Basic Certificate in Quality and Safety; participation in six 2-day learning sessions on key HSS topics; completion of a QI project; and participation in three online graduate courses. OUTCOMES: Twenty-seven faculty from four health science programs completed the program. All completed their QI projects. Nineteen (70%) have been formally engaged in the design and delivery of the medical student curriculum in HSS. Early into their training, TQA participants began to apply new knowledge and skills in HSS to the development of educational initiatives beyond the medical student curriculum. NEXT STEPS: Important next steps for TQA participants and program planners include further incorporation as faculty advisors and contributors to the full implementation of the longitudinal HSS curriculum; expanded involvement with the Leaders in Innovative Care Scholars student leadership distinction track; continued in-depth evaluation of the impact of TQA participation on patient care, teaching, and role modeling; and the recruitment of the next cohort of TQA participants.",2016-12,13/11/2018 10:47,14/04/2020 08:34,,1655-1660,,12,91,,Acad Med,,,,,,,,eng,,,,,,,PMID: 27332866 PMCID: PMC5131690,,,,"Humans; *Population Health; Female; Male; Middle Aged; Interdisciplinary Communication; *Leadership; North Carolina; 00; Academic Medical Centers/*standards; Curriculum/*standards; Education, Medical/*standards; Faculty, Medical/*standards; Patient Safety/standards; Quality Improvement/*standards; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, S6HL52R8,journalArticle,2015,"Bennett, Brian J.; Hall, Kevin D.; Hu, Frank B.; McCartney, Anne L.; Roberto, Christina",Nutrition and the science of disease prevention: a systems approach to support metabolic health.,Annals of the New York Academy of Sciences,,1749-6632 0077-8923,10.1111/nyas.12945,,"Progress in nutritional science, genetics, computer science, and behavioral economics can be leveraged to address the challenge of noncommunicable disease. This report highlights the connection between nutrition and the complex science of preventing disease and discusses the promotion of optimal metabolic health, building on input from several complementary disciplines. The discussion focuses on (1) the basic science of optimal metabolic health, including data from gene-diet interactions, microbiome, and epidemiological research in nutrition, with the goal of defining better targets and interventions, and (2) how nutrition, from pharma to lifestyle, can build on systems science to address complex issues.",2015-09,13/11/2018 10:47,14/04/2020 08:34,,01-Dec,,,1352,,Ann N Y Acad Sci,,,,,,,,eng,(c) 2015 New York Academy of Sciences.,,,,,,PMID: 26415028 PMCID: PMC5298925,,,,Humans; systems science; Animals; *Gene-Environment Interaction; obesity; *Life Style; *Metabolic Diseases/epidemiology/genetics/metabolism/prevention & control; *Microbiota; body weight; diabetes; gene-diet interactions; gut microbiome; Nutritional Sciences/methods; 00; ******To read; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, R3TNGBPB,journalArticle,2015,"Jolley, Rachel J.; Quan, Hude; Jette, Nathalie; Sawka, Keri Jo; Diep, Lucy; Goliath, Jade; Roberts, Derek J.; Yipp, Bryan G.; Doig, Christopher J.",Validation and optimisation of an ICD-10-coded case definition for sepsis using administrative health data.,BMJ open,,2044-6055 2044-6055,10.1136/bmjopen-2015-009487,,"OBJECTIVE: Administrative health data are important for health services and outcomes research. We optimised and validated in intensive care unit (ICU) patients an International Classification of Disease (ICD)-coded case definition for sepsis, and compared this with an existing definition. We also assessed the definition's performance in non-ICU (ward) patients. SETTING AND PARTICIPANTS: All adults (aged >/= 18 years) admitted to a multisystem ICU with general medicosurgical ICU care from one of three tertiary care centres in the Calgary region in Alberta, Canada, between 1 January 2009 and 31 December 2012 were included. RESEARCH DESIGN: Patient medical records were randomly selected and linked to the discharge abstract database. In ICU patients, we validated the Canadian Institute for Health Information (CIHI) ICD-10-CA (Canadian Revision)-coded definition for sepsis and severe sepsis against a reference standard medical chart review, and optimised this algorithm through examination of other conditions apparent in sepsis. MEASURES: Sensitivity (Sn), specificity (Sp), positive predictive value (PPV) and negative predictive value (NPV) were calculated. RESULTS: Sepsis was present in 604 of 1001 ICU patients (60.4%). The CIHI ICD-10-CA-coded definition for sepsis had Sn (46.4%), Sp (98.7%), PPV (98.2%) and NPV (54.7%); and for severe sepsis had Sn (47.2%), Sp (97.5%), PPV (95.3%) and NPV (63.2%). The optimised ICD-coded algorithm for sepsis increased Sn by 25.5% and NPV by 11.9% with slightly lowered Sp (85.4%) and PPV (88.2%). For severe sepsis both Sn (65.1%) and NPV (70.1%) increased, while Sp (88.2%) and PPV (85.6%) decreased slightly. CONCLUSIONS: This study demonstrates that sepsis is highly undercoded in administrative data, thus under-ascertaining the true incidence of sepsis. The optimised ICD-coded definition has a higher validity with higher Sn and should be preferentially considered if used for surveillance purposes.",23/12/2015,13/11/2018 10:47,14/04/2020 08:34,,e009487,,12,5,,BMJ Open,,,,,,,,eng,Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/,,,,,,PMID: 26700284 PMCID: PMC4691777,,,,"Humans; Canada; Female; Male; Middle Aged; Aged; Algorithms; Severity of Illness Index; Sensitivity and Specificity; Sepsis/*diagnosis; Hospitalization; International Classification of Diseases; Databases, Factual; Administrative Data; Clinical Coding/*standards; Diagnosis Validation; Intensive Care Units/*organization & administration; International Classification of Disease; Medical Records/*standards; Patient Care/Classification; Patient Discharge; Sepsis; Tertiary Care Centers; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4FVT2HFP,journalArticle,2016,"Mileder, Lukas P.; Schmolzer, Georg M.",Simulation-based training: the missing link to lastingly improved patient safety and health?,Postgraduate medical journal,,1469-0756 0032-5473,10.1136/postgradmedj-2015-133732,,,2016-06,13/11/2018 10:47,14/04/2020 08:34,,309-311,,1088,92,,Postgrad Med J,,,,,,,,eng,,,,,,,PMID: 26929391,,,,Humans; Patient Safety/*standards; Simulation Training/*methods; Quality Improvement; *Staff Development/methods/organization & administration; MEDICAL EDUCATION & TRAINING; Medical Errors/*prevention & control; Safety Management/methods/organization & administration; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QGDN7VBS,journalArticle,2016,"Rojo, E.; Maestre, J. M.; Diaz-Mendi, A. R.; Ansorena, L.; Del Moral, I.",[Innovation in healthcare processes and patient safety using clinical simulation].,Revista de calidad asistencial : organo de la Sociedad Espanola de Calidad Asistencial,,1887-1364 1134-282X,10.1016/j.cali.2015.12.008,,"OBJECTIVE: Many excellent ideas are never implemented or generalised by healthcare organisations. There are two related paradigms: thinking that individuals primarily change through accumulating knowledge, and believing that the dissemination of that knowledge within the organisation is the key element to facilitate change. As an alternative, a description and evaluation of a simulation-based inter-professional team training program conducted in a Regional Health Service to promote and facilitate change is presented. MATERIAL AND METHODS: The Department of Continuing Education completed the needs assessment using the proposals presented by clinical units and management. Skills and behaviors that could be learned using simulation were selected, and all personnel from the units participating were included. Experiential learning principles based on clinical simulation and debriefing, were used for the instructional design. The Kirkpatrick model was used to evaluate the program. RESULTS: Objectives included: a) decision-making and teamwork skills training in high prevalence diseases with a high rate of preventable complications; b) care processes reorganisation to improve efficiency, while maintaining patient safety; and, c) implementation of new complex techniques with a long learning curve, and high preventable complications rate. Thirty clinical units organised 39 training programs in the 3 public hospitals, and primary care of the Regional Health Service during 2013-2014. Over 1,559 healthcare professionals participated, including nursing assistants, nurses and physicians. CONCLUSION: Simulation in healthcare to train inter-professional teams can promote and facilitate change in patient care, and organisational re-engineering.",2016-10,13/11/2018 10:47,14/04/2020 08:35,,267-278,,5,31,,Rev Calid Asist,,,,,,,,spa,"Copyright (c) 2016 SECA. Publicado por Elsevier Espana, S.L.U. All rights reserved.",,,,,,PMID: 26965531,,,,Humans; Patient Care Team; *Delivery of Health Care; *Patient Safety; Health Personnel; Patient simulation; 00; Cultura organizacional; Debriefing; Gestion del cambio; Innovacion organizacional; Organisational change; Organisational culture; Organisational innovation; Programas de entrenamiento; Simulacion clinica; Training programs; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RLV8BCXG,journalArticle,2016,"Hassmiller Lich, Kriste; Frerichs, Leah; Fishbein, Diana; Bobashev, Georgiy; Pentz, Mary Ann",Translating research into prevention of high-risk behaviors in the presence of complex systems: definitions and systems frameworks.,Translational behavioral medicine,,1613-9860 1613-9860,10.1007/s13142-016-0390-z,,"To impact population health, it is critical to collaborate across disciplinary and practice-based silos and integrate resources, experiences, and knowledge to exert positive change. Complex systems shape both the prevention outcomes researchers, practitioners, and policymakers seek to impact and how research is translated and can either impede or support movement from basic scientific discovery to impactful and scaled-up prevention practice. Systems science methods can be used to facilitate designing translation support that is grounded in a richer understanding of the many interacting forces affecting prevention outcomes across contexts. In this paper, we illustrate how one systems science method, system dynamics, could be used to advance research, practice, and policy initiatives in each stage of translation from discovery to translation of innovation into global communities (T0-T5), with tobacco prevention as an example. System dynamics can be applied to each translational stage to integrate disciplinary knowledge and document testable hypotheses to inform translation research and practice.",2016-03,13/11/2018 10:47,14/04/2020 08:34,,17-31,,1,6,,Transl Behav Med,,,,,,,,eng,,,,,,,PMID: 27012250 PMCID: PMC4807191,,,,"Humans; Health Policy; Decision Making; Models, Theoretical; System dynamics; *Risk-Taking; Behavioral disorders; Dynamic complexity; Prevention science; Preventive Health Services/*methods; Tobacco Use Disorder/prevention & control; Tobacco Use/prevention & control; Translational Medical Research/*methods; Translational research; Translational stages; 1; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7EN5QLQ6,journalArticle,2016,"Laurence, Caroline O.; Karnon, Jonathan","Improving the planning of the GP workforce in Australia: a simulation model incorporating work transitions, health need and service usage.",Human resources for health,,1478-4491 1478-4491,10.1186/s12960-016-0110-2,,"BACKGROUND: In Australia, the approach to health workforce planning has been supply-led and resource-driven rather than need-based. The result has been cycles of shortages and oversupply. These approaches have tended to use age and sex projections as a measure of need or demand for health care. Less attention has been given to more complex aspects of the population, such as the increasing proportion of the ageing population and increasing levels of chronic diseases or changes in the mix of health care providers or their productivity levels. These are difficult measures to get right and so are often avoided. This study aims to develop a simulation model for planning the general practice workforce in South Australia that incorporates work transitions, health need and service usage. METHODS: A simulation model was developed with two sub-models--a supply sub-model and a need sub-model. The supply sub-model comprised three components--training, supply and productivity--and the need sub-model described population size, health needs, service utilisation rates and productivity. A state transition cohort model is used to estimate the future supply of GPs, accounting for entries and exits from the workforce and changes in location and work status. In estimating the required number of GPs, the model used incidence and prevalence data, combined with age, gender and condition-specific utilisation rates. The model was run under alternative assumptions reflecting potential changes in need and utilisation rates over time. RESULTS: The supply sub-model estimated the number of full-time equivalent (FTE) GP stock in SA for the period 2004-2011 and was similar to the observed data, although it had a tendency to overestimate the GP stock. The three scenarios presented for the demand sub-model resulted in different outcomes for the estimated required number of GPs. For scenario one, where utilisation rates in 2003 were assumed optimal, the model predicted fewer FTE GPs were required than was observed. In scenario 2, where utilisation rates in 2013 were assumed optimal, the model matched observed data, and in scenario 3, which assumed increasing age- and gender-specific needs over time, the model predicted more FTE GPs were required than was observed. CONCLUSIONS: This study provides a robust methodology for determining supply and demand for one professional group at a state level. The supply sub-model was fitted to accurately represent workforce behaviours. In terms of demand, the scenario analysis showed variation in the estimations under different assumptions that demonstrates the value of monitoring population-based need over time. In the meantime, expert opinion might identify the most relevant scenario to be used in projecting workforce requirements.",11/04/2016,13/11/2018 10:47,14/04/2020 08:34,,13,,,14,,Hum Resour Health,,,,,,,,eng,,,,,,,PMID: 27067272 PMCID: PMC4828877,,,,"Humans; Female; Male; Australia; *Models, Theoretical; Markov chain; Health Services Needs and Demand; discrete event simulation; *General Practitioners; *Health Planning/standards; Delivery of Health Care/*manpower/utilization; General practice; General Practice/*manpower; Health needs; Health Services/*manpower/utilization; Health workforce; Simulation model; Utilisation; 1; 320",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2Y4TUG3P,journalArticle,2016,"Kittipittayakorn, Cholada; Ying, Kuo-Ching",Using the Integration of Discrete Event and Agent-Based Simulation to Enhance Outpatient Service Quality in an Orthopedic Department.,Journal of healthcare engineering,,2040-2295 2040-2295,10.1155/2016/4189206,,"Many hospitals are currently paying more attention to patient satisfaction since it is an important service quality index. Many Asian countries' healthcare systems have a mixed-type registration, accepting both walk-in patients and scheduled patients. This complex registration system causes a long patient waiting time in outpatient clinics. Different approaches have been proposed to reduce the waiting time. This study uses the integration of discrete event simulation (DES) and agent-based simulation (ABS) to improve patient waiting time and is the first attempt to apply this approach to solve this key problem faced by orthopedic departments. From the data collected, patient behaviors are modeled and incorporated into a massive agent-based simulation. The proposed approach is an aid for analyzing and modifying orthopedic department processes, allows us to consider far more details, and provides more reliable results. After applying the proposed approach, the total waiting time of the orthopedic department fell from 1246.39 minutes to 847.21 minutes. Thus, using the correct simulation model significantly reduces patient waiting time in an orthopedic department.",2016,13/11/2018 10:47,14/04/2020 08:34,,,,,2016,,J Healthc Eng,,,,,,,,eng,,,,,,,PMID: 27195606 PMCID: PMC5058573,,,,"Humans; *Computer Simulation; Ambulatory Care; Process Assessment (Health Care); Quality Assurance, Health Care/*organization & administration; 1; *Patient Satisfaction; Orthopedics; 320; Discrete Event; Agent-Based",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VLG2X46X,journalArticle,2016,"Vasylyeva, Tetyana I.; Friedman, Samuel R.; Paraskevis, Dimitrios; Magiorkinis, Gkikas",Integrating molecular epidemiology and social network analysis to study infectious diseases: Towards a socio-molecular era for public health.,"Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases",,1567-7257 1567-1348,10.1016/j.meegid.2016.05.042,,"The number of public health applications for molecular epidemiology and social network analysis has increased rapidly since the improvement in computational capacities and the development of new sequencing techniques. Currently, molecular epidemiology methods are used in a variety of settings: from infectious disease surveillance systems to the description of disease transmission pathways. The latter are of great epidemiological importance as they let us describe how a virus spreads in a community, make predictions for the further epidemic developments, and plan preventive interventions. Social network methods are used to understand how infections spread through communities and what the risk factors for this are, as well as in improved contact tracing and message-dissemination interventions. Research is needed on how to combine molecular and social network data as both include essential, but not fully sufficient information on infection transmission pathways. The main differences between the two data sources are that, firstly, social network data include uninfected individuals unlike the molecular data sampled only from infected network members. Thus, social network data include more detailed picture of a network and can improve inferences made from molecular data. Secondly, network data refer to the current state and interactions within the social network, while molecular data refer to the time points when transmissions happened, which might have happened years before the sampling date. As of today, there have been attempts to combine and compare the data obtained from the two sources. Even though there is no consensus on whether and how social and genetic data complement each other, this research might significantly improve our understanding of how viruses spread through communities.",2016-12,13/11/2018 10:47,14/04/2020 08:35,,248-255,,,46,,Infect Genet Evol,,,,,,,,eng,Copyright A(c) 2016 The Authors. Published by Elsevier B.V. All rights reserved.,,,,,,PMID: 27262354 PMCID: PMC5135626,,,,Humans; Risk Factors; *Social Networking; 00; *Infectious diseases; *Molecular epidemiology; *Molecular Epidemiology; *Phylodynamics; *Phylogenetics; *Social networks; *Viruses; Communicable Diseases/*epidemiology/*transmission; Phylogeny; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NH33GE56,journalArticle,2016,"Amed, Shazhan; Shea, Stephanie; Pinkney, Susan; Wharf Higgins, Joan; Naylor, Patti-Jean",Wayfinding the Live 5-2-1-0 Initiative-At the Intersection between Systems Thinking and Community-Based Childhood Obesity Prevention.,International journal of environmental research and public health,,1660-4601 1660-4601,10.3390/ijerph13060614,,"Childhood obesity is complex and requires a 'systems approach' that collectively engages across multiple community settings. Sustainable Childhood Obesity Prevention through Community Engagement (SCOPE) has implemented Live 5-2-1-0-a multi-sector, multi-component childhood obesity prevention initiative informed by systems thinking and participatory research via an innovative knowledge translation (KT) model (RE-FRAME). This paper describes the protocol for implementing and evaluating RE-FRAME in two 'existing' (>2 years of implementation) and two 'new' Live 5-2-1-0 communities to understand how to facilitate and sustain systems/community-level change. In this mixed-methods study, RE-FRAME was implemented via online resources, webinars, a backbone organization (SCOPE) coordinating the initiative, and a linking system supporting KT. Qualitative and quantitative data were collected using surveys and stakeholder interviews, analyzed using thematic analysis and descriptive statistics, respectively. Existing communities described the consistency of Live",21/06/2016,13/11/2018 10:47,14/04/2020 08:34,,,,6,13,,Int J Environ Res Public Health,,,,,,,,eng,,,,,,,PMID: 27338432 PMCID: PMC4924071,,,,Humans; Surveys and Questionnaires; Systems Analysis; Community Participation; *childhood obesity; *collective impact; *health promotion; *participatory research; Health Promotion/*methods; Pediatric Obesity/*prevention & control; Residence Characteristics; Translational Medical Research; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VVHBSMY2,journalArticle,2016,"McNab, Duncan; Bowie, Paul; Morrison, Jill; Ross, Alastair",Understanding patient safety performance and educational needs using the 'Safety-II' approach for complex systems.,"Education for primary care : an official publication of the Association of Course Organisers, National Association of GP Tutors, World Organisation of Family Doctors",,1475-990X 1473-9879,10.1080/14739879.2016.1246068,,"Participation in projects to improve patient safety is a key component of general practice (GP) specialty training, appraisal and revalidation. Patient safety training priorities for GPs at all career stages are described in the Royal College of General Practitioners' curriculum. Current methods that are taught and employed to improve safety often use a 'find-and-fix' approach to identify components of a system (including humans) where performance could be improved. However, the complex interactions and inter-dependence between components in healthcare systems mean that cause and effect are not always linked in a predictable manner. The Safety-II approach has been proposed as a new way to understand how safety is achieved in complex systems that may improve quality and safety initiatives and enhance GP and trainee curriculum coverage. Safety-II aims to maximise the number of events with a successful outcome by exploring everyday work. Work-as-done often differs from work-as-imagined in protocols and guidelines and various ways to achieve success, dependent on work conditions, may be possible. Traditional approaches to improve the quality and safety of care often aim to constrain variability but understanding and managing variability may be a more beneficial approach. The application of a Safety-II approach to incident investigation, quality improvement projects, prospective analysis of risk in systems and performance indicators may offer improved insight into system performance leading to more effective change. The way forward may be to combine the Safety-II approach with 'traditional' methods to enhance patient safety training, outcomes and curriculum coverage.",2016-11,13/11/2018 10:47,14/04/2020 08:34,,443-450,,6,27,,Educ Prim Care,,,,,,,,eng,,,,,,,PMID: 27800711,,,,Humans; Patient Safety; Curriculum; Safety; *Patient Safety; Quality Improvement; United Kingdom; Patient safety; complex systems; Delivery of Health Care/organization & administration/standards; General Practice/education; General Practitioners/*education; incident investigation; Medical Errors; quality improvement; Safety-II; Ergonomics; 1; Information Needs; Patient Safety – Methods; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KP4MU6BU,journalArticle,2017,"Levy, David T.; Mays, Darren; Yuan, Zhe; Hammond, David; Thrasher, James F.",Public health benefits from pictorial health warnings on US cigarette packs: a SimSmoke simulation.,Tobacco control,,1468-3318 0964-4563,10.1136/tobaccocontrol-2016-053087,,"INTRODUCTION: While many countries have adopted prominent pictorial warning labels (PWLs) for cigarette packs, the USA still requires only small, text-only labels located on one side of the cigarette pack that have little effect on smoking-related outcomes. Tobacco industry litigation blocked implementation of a 2011 Food and Drug Administration's (FDA) rule requiring large PWLs. To inform FDA action on PWLs, this study provides research-based estimates of their public health impacts. METHODS: Literature was reviewed to identify the impact of cigarette PWLs on smoking prevalence, cessation and initiation. Based on this analysis, the SimSmoke model was used to estimate the effect of requiring PWLs in the USA on smoking prevalence and, using standard attribution methods, on smoking-attributable deaths (SADs) and key maternal and child health outcomes. RESULTS: Available research consistently shows a direct association between PWLs and increased cessation and reduced smoking initiation and prevalence. The SimSmoke model projects that PWLs would reduce smoking prevalence by 5% (2.5%-9%) relative to the status quo over the short term and by 10% (4%-19%) over the long term. Over the next 50 years, PWLs are projected to avert 652 800 (327 000-1 190 500) SADs, 46 600 (17 500-92 300) low-birth-weight cases, 73 600 (27 800-145 100) preterm births and 1000 (400-2000) cases of sudden infant death syndrome. CONCLUSIONS: Requiring PWLs on all US cigarette packs would be appropriate for the protection of the public health, because it would substantially reduce smoking prevalence and thereby reduce SADs and the morbidity and medical costs associated with adverse smoking-attributable birth outcomes.",2017-11,13/11/2018 10:47,14/04/2020 08:34,,649-655,,6,26,,Tob Control,,,,,,,,eng,Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.,,,,,,PMID: 27807299 PMCID: PMC5966722,,,,Humans; United States; *Computer Simulation; Prevalence; *Packaging and Labelling; *Pictorial Works as Topic; *Public policy; *Surveillance and monitoring; Child Health/statistics & numerical data; Cigarette Smoking/*adverse effects/*epidemiology; Maternal Health/statistics & numerical data; Product Labeling/*legislation & jurisprudence; Public Health/*legislation & jurisprudence; Smoking Prevention/*methods; 1; 210,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7UZ5QEP3,journalArticle,2016,"Kimani, Tabitha; Schelling, Esther; Bett, Bernard; Ngigi, Margaret; Randolph, Tom; Fuhrimann, Samuel",Public Health Benefits from Livestock Rift Valley Fever Control: A Simulation of Two Epidemics in Kenya.,EcoHealth,,1612-9210 1612-9202,10.1007/s10393-016-1192-y,,"In controlling Rift Valley fever, public health sector optimises health benefits by considering cost-effective control options. We modelled cost-effectiveness of livestock RVF control from a public health perspective in Kenya. Analysis was limited to pastoral and agro-pastoral system high-risk areas, for a 10-year period incorporating two epidemics: 2006/2007 and a hypothetical one in 2014/2015. Four integrated strategies (baseline and alternatives), combined from three vaccination and two surveillance options, were compared. Baseline strategy included annual vaccination of 1.2-11% animals plus passive surveillance and monitoring of nine sentinel herds. Compared to the baseline, two alternatives assumed improved vaccination coverage. A herd dynamic RVF animal simulation model produced number of animals infected under each strategy. A second mathematical model implemented in R estimated number people who would be infected by the infected animals. The 2006/2007 RVF epidemic resulted in 3974 undiscounted, unweighted disability adjusted life years (DALYs). Improving vaccination coverage to 41-51% (2012) and 27-33% (2014) 3 years before the hypothetical 2014/2015 outbreak can avert close to 1200 DALYs. Improved vaccinations showed cost-effectiveness (CE) values of US$ 43-53 per DALY averted. The baseline practice is not cost-effective to the public health sector.",2016-12,13/11/2018 10:47,14/04/2020 08:34,,729-742,,4,13,,Ecohealth,,,,,,,,eng,,,,,,,PMID: 27830387 PMCID: PMC5161764,,,,Humans; *public health; *benefits; *livestock; *Livestock; *Rift Valley fever; Animals; Disease Outbreaks/*prevention & control; Epidemics; Kenya; Rift Valley Fever/*prevention & control; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CDXZPWYQ,journalArticle,2017,"Liu, Zhanmin; Lu, Xiaohui; Feng, Junlan; Fan, Qianzhu; Zhang, Yan; Yang, Xin",Influence of Ship Emissions on Urban Air Quality: A Comprehensive Study Using Highly Time-Resolved Online Measurements and Numerical Simulation in Shanghai.,Environmental science & technology,,1520-5851 0013-936X,10.1021/acs.est.6b03834,,"Shanghai has become an international shipping center in the world. In this study, the multiyear measurements and the high resolution air quality model with hourly ship emission inventory were combined to determine the influence of ship emissions on urban Shanghai. The aerosol time-of-flight mass spectrometer (ATOFMS) measurements were carried out at an urban site from April 2009 to January 2013. During the entire sampling time, most of the half-hourly averaged number fractions of primary ship emitted particles varied between 1.0-10.0%. However, the number fraction could reach up to 50% during the ship plume cases. Ship-plume-influenced periods usually occurred in spring and summer. The simulation of Weather Research and Forecasting/Community Multiscale Air Quality model (WRF/CMAQ) with hourly ship emission inventory provided the highly time-resolved concentrations of ship-related air pollutants during a ship plume case. It showed ships could contribute 20-30% (2-7 mug/m(3)) of the total PM2.5 within tens of kilometers of coastal and riverside Shanghai during ship-plume-influenced periods. Our results showed that ship emissions have substantial contribution to the air pollution in urban Shanghai. The control measures of ship emission should be taken considering its negative environment and human health effects.",03/01/2017,13/11/2018 10:47,14/04/2020 08:34,,202-211,,1,51,,Environ Sci Technol,,,,,,,,eng,,,,,,,PMID: 27933806,,,,Humans; China; 00; *Ships; *Vehicle Emissions; Air Pollutants; Environmental Monitoring; Particulate Matter; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, B8Y3LKF7,journalArticle,2016,"Enanoria, Wayne T. A.; Liu, Fengchen; Zipprich, Jennifer; Harriman, Kathleen; Ackley, Sarah; Blumberg, Seth; Worden, Lee; Porco, Travis C.",The Effect of Contact Investigations and Public Health Interventions in the Control and Prevention of Measles Transmission: A Simulation Study.,PloS one,,1932-6203 1932-6203,10.1371/journal.pone.0167160,,"BACKGROUND: Measles cases continue to occur despite its elimination status in the United States. To control transmission, public health officials confirm the measles diagnosis, identify close contacts of infectious cases, deliver public health interventions (i.e., post-exposure prophylaxis) among those who are eligible, and follow-up with the close contacts to determine overall health outcomes. A stochastic network simulation of measles contact tracing was conducted using existing agent-based modeling software and a synthetic population with high levels of immunity in order to estimate the impact of different interventions in controlling measles transmission. METHODS AND FINDINGS: The synthetic population was created to simulate California`s population in terms of population demographics, household, workplace, school, and neighborhood characteristics using California Department of Finance 2010 census data. Parameters for the model were obtained from a review of the literature, California measles case surveillance data, and expert opinion. Eight different scenarios defined by the use of three different public health interventions were evaluated: (a) post-exposure measles, mumps, and rubella (MMR) vaccine, (b) post-exposure immune globulin (IG), and (c) voluntary isolation and home quarantine in the presence or absence of public health response delays. Voluntary isolation and home quarantine coupled with one or two other interventions had the greatest reduction in the number of secondary cases infected by the index case and the probability of escape situations (i.e., the outbreak continues after 90 days). CONCLUSIONS: Interrupting contact patterns via voluntary isolation and home quarantine are particularly important in reducing the number of secondary cases infected by the index case and the probability of uncontrolled outbreaks.",2016,13/11/2018 10:47,14/04/2020 08:34,,e0167160,,12,11,,PLoS One,,,,,,,,eng,,,,,,,PMID: 27941976 PMCID: PMC5152814,,,,"Humans; Outcome Assessment (Health Care); *Public Health Surveillance; Computer Simulation; Models, Theoretical; *Contact Tracing; *Early Medical Intervention; *Sentinel Surveillance; California/epidemiology; Disease Outbreaks; Measles Vaccine/immunology; Measles/epidemiology/*prevention & control/*transmission; Post-Exposure Prophylaxis; Quarantine; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, S6IX4RR5,journalArticle,2016,"Kirsch, Florian",Economic Evaluations of Multicomponent Disease Management Programs with Markov Models: A Systematic Review.,Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research,,1524-4733 1098-3015,10.1016/j.jval.2016.07.004,,"BACKGROUND: Disease management programs (DMPs) for chronic diseases are being increasingly implemented worldwide. OBJECTIVES: To present a systematic overview of the economic effects of DMPs with Markov models. The quality of the models is assessed, the method by which the DMP intervention is incorporated into the model is examined, and the differences in the structure and data used in the models are considered. METHODS: A literature search was conducted; the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement was followed to ensure systematic selection of the articles. Study characteristics e.g. results, the intensity of the DMP and usual care, model design, time horizon, discount rates, utility measures, and cost-of-illness were extracted from the reviewed studies. Model quality was assessed by two researchers with two different appraisals: one proposed by Philips et al. (Good practice guidelines for decision-analytic modelling in health technology assessment: a review and consolidation of quality asessment. Pharmacoeconomics 2006;24:355-71) and the other proposed by Caro et al. (Questionnaire to assess relevance and credibility of modeling studies for informing health care decision making: an ISPOR-AMCP-NPC Good Practice Task Force report. Value Health 2014;17:174-82). RESULTS: A total of 16 studies (9 on chronic heart disease, 2 on asthma, and 5 on diabetes) met the inclusion criteria. Five studies reported cost savings and 11 studies reported additional costs. In the quality, the overall score of the models ranged from 39% to 65%, it ranged from 34% to 52%. Eleven models integrated effectiveness derived from a clinical trial or a meta-analysis of complete DMPs and only five models combined intervention effects from different sources into a DMP. The main limitations of the models are bad reporting practice and the variation in the selection of input parameters. CONCLUSIONS: Eleven of the 14 studies reported cost-effectiveness results of less than $30,000 per quality-adjusted life-year and the remaining two studies less than $30,000 per life-year gained. Nevertheless, if the reporting and selection of data problems are addressed, then Markov models should provide more reliable information for decision makers, because understanding under what circumstances a DMP is cost-effective is an important determinant of efficient resource allocation.",2016-12,13/11/2018 10:47,14/04/2020 08:34,,1039-1054,,8,19,,Value Health,,,,,,,,eng,Copyright (c) 2016 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.,,,,,,PMID: 27987631,,,,"Humans; Cost-Benefit Analysis; Decision Support Techniques; *Markov Chains; Cost of Illness; *Disease Management; *cost-effectiveness; *Models, Econometric; *chronic disease; *DMP; *Markov model; *review; Asthma/economics/therapy; Chronic Disease/*economics/*therapy; Diabetes Mellitus/economics/therapy; Heart Diseases/economics/therapy; 1; ******To read; Markov; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PJ84ZB58,journalArticle,2017,"Carney, Timothy Jay; Shea, Christopher Michael",Informatics Metrics and Measures for a Smart Public Health Systems Approach: Information Science Perspective.,Computational and mathematical methods in medicine,,1748-6718 1748-670X,10.1155/2017/1452415,,"Public health informatics is an evolving domain in which practices constantly change to meet the demands of a highly complex public health and healthcare delivery system. Given the emergence of various concepts, such as learning health systems, smart health systems, and adaptive complex health systems, health informatics professionals would benefit from a common set of measures and capabilities to inform our modeling, measuring, and managing of health system ""smartness."" Here, we introduce the concepts of organizational complexity, problem/issue complexity, and situational awareness as three codependent drivers of smart public health systems characteristics. We also propose seven smart public health systems measures and capabilities that are important in a public health informatics professional's toolkit.",2017,13/11/2018 10:47,14/04/2020 08:34,,1452415,,,2017,,Comput Math Methods Med,,,,,,,,eng,,,,,,,PMID: 28167999 PMCID: PMC5259665,,,,"Humans; Health Services Research; Delivery of Health Care; Risk Assessment; Systems Analysis; Algorithms; Cognition; Models, Organizational; 1; Public Health Informatics/*instrumentation/methods; Public Health/*instrumentation/methods; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 34P65B9D,journalArticle,2017,"Escher, Cecilia; Creutzfeldt, Johan; Meurling, Lisbet; Hedman, Leif; Kjellin, Ann; Fellander-Tsai, Li",Medical students' situational motivation to participate in simulation based team training is predicted by attitudes to patient safety.,BMC medical education,,1472-6920 1472-6920,10.1186/s12909-017-0876-5,,"BACKGROUND: Patient safety education, as well as the safety climate at clinical rotations, has an impact on students' attitudes. We explored medical students' self-reported motivation to participate in simulation-based teamwork training (SBTT), with the hypothesis that high scores in patient safety attitudes would promote motivation to SBTT and that intrinsic motivation would increase after training. METHODS: In a prospective cohort study we explored Swedish medical students' attitudes to patient safety, their motivation to participate in SBTT and how motivation was affected by the training. The setting was an integrated SBTT course during the surgical semester that focused on non-technical skills and safe treatment of surgical emergencies. Data was collected using the Situational Motivation Scale (SIMS) and the Attitudes to Patient Safety Questionnaire (APSQ). RESULTS: We found a positive correlation between students' individual patient safety attitudes and self-reported motivation (identified regulation) to participate in SBTT. We also found that intrinsic motivation increased after training. Female students in our study scored higher than males regarding some of the APSQ sub-scores and the entire group scored higher or on par with comparable international samples. CONCLUSION: In order to enable safe practice and professionalism in healthcare, students' engagement in patient safety education is important. Our finding that students' patient safety attitudes show a positive correlation to motivation and that intrinsic motivation increases after training underpins patient safety climate and integrated teaching of patient safety issues at medical schools in order to help students develop the knowledge, skills and attitudes required for safe practice.",10/02/2017,13/11/2018 10:47,14/04/2020 08:34,,37,,1,17,,BMC Med Educ,,,,,,,,eng,,,,,,,PMID: 28183316 PMCID: PMC5301395,,,,"Humans; *Simulation Training; Adult; Female; Male; Middle Aged; Young Adult; Patient Safety/*standards; Sweden; *Attitude of Health Personnel; General Surgery/education; Motivation; Patient safety; Prospective Studies; Surgery; Teamwork; 00; Attitudes; Clinical performance; Crew resource management; Education, Medical, Undergraduate/methods/*standards; Emergency Treatment/methods/*standards; Medical education; Patient Care Team/organization & administration/standards; Perioperative Period/adverse effects; Simulator; Situational motivation; Students, Medical/*psychology; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RSDMF3B7,journalArticle,2016,"Yager, Phoebe; Collins, Corey; Blais, Carlene; O'Connor, Kathy; Donovan, Patricia; Martinez, Maureen; Cummings, Brian; Hartnick, Christopher; Noviski, Natan",Quality improvement utilizing in-situ simulation for a dual-hospital pediatric code response team.,International journal of pediatric otorhinolaryngology,,1872-8464 0165-5876,10.1016/j.ijporl.2016.06.026,,"OBJECTIVE: Given the rarity of in-hospital pediatric emergency events, identification of gaps and inefficiencies in the code response can be difficult. In-situ, simulation-based medical education programs can identify unrecognized systems-based challenges. We hypothesized that developing an in-situ, simulation-based pediatric emergency response program would identify latent inefficiencies in a complex, dual-hospital pediatric code response system and allow rapid intervention testing to improve performance before implementation at an institutional level. METHODS: Pediatric leadership from two hospitals with a shared pediatric code response team employed the Institute for Healthcare Improvement's (IHI) Breakthrough Model for Collaborative Improvement to design a program consisting of Plan-Do-Study-Act cycles occurring in a simulated environment. The objectives of the program were to 1) identify inefficiencies in our pediatric code response; 2) correlate to current workflow; 3) employ an iterative process to test quality improvement interventions in a safe environment; and 4) measure performance before actual implementation at the institutional level. RESULTS: Twelve dual-hospital, in-situ, simulated, pediatric emergencies occurred over one year. The initial simulated event allowed identification of inefficiencies including delayed provider response, delayed initiation of cardiopulmonary resuscitation (CPR), and delayed vascular access. These gaps were linked to process issues including unreliable code pager activation, slow elevator response, and lack of responder familiarity with layout and contents of code cart. From first to last simulation with multiple simulated process improvements, code response time for secondary providers coming from the second hospital decreased from 29 to 7 min, time to CPR initiation decreased from 90 to 15 s, and vascular access obtainment decreased from 15 to 3 min. Some of these simulated process improvements were adopted into the institutional response while others continue to be trended over time for evidence that observed changes represent a true new state of control. CONCLUSIONS: Utilizing the IHI's Breakthrough Model, we developed a simulation-based program to 1) successfully identify gaps and inefficiencies in a complex, dual-hospital, pediatric code response system and 2) provide an environment in which to safely test quality improvement interventions before institutional dissemination.",2016-09,13/11/2018 10:47,14/04/2020 08:35,,42-46,,,88,,Int J Pediatr Otorhinolaryngol,,,,,,,,eng,Copyright (c) 2016 Elsevier Ireland Ltd. All rights reserved.,,,,,,PMID: 27497385,,,,"Humans; *Quality Improvement; Child; *Education; *Simulation; *Pediatrics; Efficiency, Organizational; Boston; 00; *Emergencies; *Emergency Medicine; *Quality improvement; Cardiopulmonary Resuscitation; Hospital Rapid Response Team/*organization & administration; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, C7N4E8U3,journalArticle,2016,"Lock, J.; Raat, H.; Peters, M.; Scholten, M.; Beijlevelt, M.; Oostenbrink, R.; Leebeek, F. W. G.; Moll, H. A.; Cnossen, M. H.",Optimization of home treatment in haemophilia: effects of transmural support by a haemophilia nurse on adherence and quality of life.,Haemophilia : the official journal of the World Federation of Hemophilia,,1365-2516 1351-8216,10.1111/hae.13043,,"BACKGROUND: Transmural support by a haemophilia nurse may improve treatment and may empower parents and patients. AIM: To measure the effect of structured home visits by a haemophilia nurse in (parents of) patient on aspects of prophylactic home treatment. METHODS: A multicentre intervention study in two paediatric haemophilia treatment centres was performed. Primary outcome measures were: adherence to prescribed treatment, health-related quality of life and behavioural scores. Secondary outcome measures were: total clotting factor consumption, self-efficacy and number of joint bleeds. RESULTS: Over a period of 22 months (median, IQR 21-23), four to seven home visits in 46 patients (mean age 9.4 +/- 4.2 years) were made. No difference in adherence to prescribed treatment was seen after the home visits when compared to baseline measurements. Both the Child Health Questionnaire (CHQ) scales on 'Role functioning - Emotional/Behavioural' (P = 0.02, d = 0.53) and 'Parental Time Impact' (P = 0.04, d = 0.33) were reduced after intervention. The disease-specific Haemo-QoL questionnaire showed improvement in domains: 'Family' (P = 0.04, d = -0.14), 'Friends' (P = 0.03, d = -0.29) and 'Perceived support' (P = 0.03, d = -0.37). Significant improvement was observed with regard to domain 'Communication' of the VERITAS-Pro scale (P = 0.03, d = -0.28). CONCLUSIONS: After a period of transmural care by a haemophilia nurse, significant but small positive effects were demonstrated with regard to communication and increase of perceived support between parents and haemophilia treatment centre. No improvement was observed in other outcome measures.",2016-11,13/11/2018 10:47,14/04/2020 08:34,,841-851,,6,22,,Haemophilia,,,,,,,,eng,(c) 2016 John Wiley & Sons Ltd.,,,,,,PMID: 27778434,,,,"Humans; Surveys and Questionnaires; Female; Male; Cohort Studies; Child; Quality of Life; Adolescent; Child, Preschool; Infant; *adherence; *quality of life; Nurses; Patient Compliance; 1; *children; *haemophilia; *home treatment; *self-efficacy; Hemophilia A/*therapy; Self Efficacy; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WV9YCWTT,journalArticle,2017,"Gignon, Maxime; Amsallem, Carole; Ammirati, Christine",Moving a hospital: simulation - a way to co-produce safety healthcare facilities.,International journal of occupational safety and ergonomics : JOSE,,2376-9130 1080-3548,10.1080/10803548.2016.1270543,,"Moving a hospital is a critical period for quality and safety of healthcare. Change is very stressful for professionals. Workers who have experienced relocation of their place of work report deterioration in health status. Building a new hospital or restructuring a unit could provide an opportunity for improving safety and value in healthcare and for ensuring better quality of worklife for the staff. We used in situ simulation to promote experiential learning by training healthcare workers in the workplace in which they are expected to use their skills. In situ simulation was a way to design, plan, assess and implement a new healthcare environment before opening its doors for patient care. We can envisage that simulation will soon be used formally to identify potential problems in healthcare delivery and in staff quality of worklife in new healthcare facilities. Simulation is a way to co-produce a safe and valuable healthcare facility.",2017-12,13/11/2018 10:47,14/04/2020 08:34,,589-591,,4,23,,Int J Occup Saf Ergon,,,,,,,,eng,,,,,,,PMID: 27935431,,,,"Humans; Simulation Training; patient safety; Hospital Administration; 00; health facility move; Health Facility Moving/*organization & administration; health personnel; patient simulation; Personnel, Hospital/*psychology; Safety Management/methods; Workplace; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YC72BKLK,journalArticle,2017,"Brunette, Veronique; Thibodeau-Jarry, Nicolas",Simulation as a Tool to Ensure Competency and Quality of Care in the Cardiac Critical Care Unit.,The Canadian journal of cardiology,,1916-7075 0828-282X,10.1016/j.cjca.2016.10.015,,"Cardiac critical care units are high-risk clinical environments. Medical emergencies are frequent and require the intervention of a cohesive, efficient, and well trained interprofessional team. In modern clinical practice there is increased emphasis on safety but also increased lack of acceptance of medical errors and as a consequence, increased litigation. In the past decade, simulation-based learning has arisen as an effective and safe means to learn and practice acute care setting skills. It has been used and studied in different contexts including procedural skills training, crisis resource management and team training, patient and family member communication skills, and health care system quality improvement. Simulation-based education is a relatively recent teaching strategy and evidence of its efficacy continues to grow. Nevertheless, many influential medical societies are now promoting a simulation-based approach for cardiovascular training and continuing medical education. In this article we review the simulation literature in the intensive care unit and evaluate its integration in coronary care units and postoperative cardiovascular intensive care units. We also provide resources for educators and clinicians who wish to implement simulation workshops in these settings.",2017-01,13/11/2018 10:47,14/04/2020 08:34,,119-127,,1,33,,Can J Cardiol,,,,,,,,eng,Copyright (c) 2016 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.,,,,,,PMID: 28024550,,,,"Humans; *Quality Assurance, Health Care; *Computer Simulation; *Clinical Competence; Education, Medical, Continuing/*methods; 1; *Coronary Care Units; Critical Care/*standards; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4TMADEDJ,journalArticle,2018,"van Wietmarschen, Herman A.; Wortelboer, Heleen M.; van der Greef, Jan",Grip on health: A complex systems approach to transform health care.,Journal of evaluation in clinical practice,,1365-2753 1356-1294,10.1111/jep.12679,,"This article addresses the urgent need for a transition in health care to deal with the increasing prevalence of chronic diseases and associated rapid rise of health care costs. Chronic diseases evolve and are predominantly related to lifestyle and environment. A shift is needed from a reductionist repair mode of thinking, toward a more integrated biopsychosocial way of thinking about health. The aim of this article is to discuss the opportunities that complexity science offer for transforming health care toward optimal treatment and prevention of chronic lifestyle diseases. Health and health care is discussed from a complexity science perspective. The benefits of concepts developed in the field of complexity science for stimulating transitions in health care are explored. Complexity science supports the elucidation of the essence of health processes. It provides a unique perspective on health with a focus on the relationships within networks of dynamically interacting factors and the emergence of health out of the organization of those relationships. Novel types of complexity science-based intervention strategies are being developed. The first application in practice is the integrated obesity treatment program currently piloted in the Netherlands, focusing on health awareness and healing relationships. Complexity science offers various theories and methods to capture the path toward unhealthy and healthy states, facilitating the development of a dynamic integrated biopsychosocial perspective on health. This perspective offers unique insights into health processes for patients and citizens. In addition, dynamic models driven by personal data provide simulations of health processes and the ability to detect transitions between health states. Such models are essential for aligning and reconnecting the many institutions and disciplines involved in the health care sector and evolve toward an integrated health care ecosystem.",2018-02,13/11/2018 10:47,14/04/2020 08:35,,269-277,,1,24,,J Eval Clin Pract,,,,,,,,eng,"(c) 2016 John Wiley & Sons, Ltd.",,,,,,PMID: 28032412,,,,"Humans; *public health; Systems Analysis; Health Promotion/methods; *Quality of Life; Health Behavior; Life Style; Netherlands/epidemiology; *Chronic Disease/epidemiology/prevention & control/psychology; *Delivery of Health Care, Integrated/methods/organization & administration; *Evidence-Based Medicine/methods/organization & administration; *health care; *patient-centered care; Transitional Care/*organization & administration; 1; Complexity science; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KMZFTF53,journalArticle,2017,"Gordon, Morris; Fell, Christopher W. R.; Box, Helen; Farrell, Michael; Stewart, Alison",Learning health 'safety' within non-technical skills interprofessional simulation education: a qualitative study.,Medical education online,,1087-2981 1087-2981,10.1080/10872981.2017.1272838,,"BACKGROUND: Healthcare increasingly recognises and focusses on the phenomena of 'safe practice' and 'patient safety.' Success with non-technical skills (NTS) training in other industries has led to widespread transposition to healthcare education, with communication and teamwork skills central to NTS frameworks. OBJECTIVE: This study set out to identify how the context of interprofessional simulation learning influences NTS acquisition and development of 'safety' amongst learners. METHODS: Participants receiving a non-technical skills (NTS) safety focussed training package were invited to take part in a focus group interview which set out to explore communication, teamwork, and the phenomenon of safety in the context of the learning experiences they had within the training programme. The analysis was aligned with a constructivist paradigm and took an interactive methodological approach. The analysis proceeded through three stages, consisting of open, axial, and selective coding, with constant comparisons taking place throughout each phase. Each stage provided categories that could be used to explore the themes of the data. Additionally, to ensure thematic saturation, transcripts of observed simulated learning encounters were then analysed. RESULTS: Six themes were established at the axial coding level, i.e., analytical skills, personal behaviours, communication, teamwork, context, and pedagogy. Underlying these themes, two principal concepts emerged, namely: intergroup contact anxiety - as both a result of and determinant of communication - and teamwork, both of which must be considered in relation to context. These concepts have subsequently been used to propose a framework for NTS learning. CONCLUSIONS: This study highlights the role of intergroup contact anxiety and teamwork as factors in NTS behaviour and its dissipation through interprofessional simulation learning. Therefore, this should be a key consideration in NTS education. Future research is needed to consider the role of the affective non-technical attributes of intergroup contact anxiety and teamwork as focuses for education and determinants of safe behaviour. ABBREVIATIONS: AUM: Anxiety/uncertainty management; NTS: Non-technical skills; TINSELS: Training in non-technical skills to enhance levels of medicines safety.",2017,13/11/2018 10:47,14/04/2020 08:34,,1272838,,1,22,,Med Educ Online,,,,,,,,eng,,,,,,,PMID: 28178920 PMCID: PMC5328384,,,,Humans; Clinical Competence; Qualitative Research; *Communication; *Interprofessional Relations; Behavior; Group Processes; Health Personnel/*education; human factors; Leadership; Patient Care Team/*organization & administration; 00; intergroup contact anxiety; Non-technical skills; simulation training; Simulation Training/*organization & administration; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6ZZW8AKU,journalArticle,2017,"Wang, W. T.; Sun, Q. H.; Qin, J.; Li, T. T.; Shi, X. M.",[Simulation study of air quality health index in 5 cities in China: 2013-2015].,Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi,,0254-6450 0254-6450,10.3760/cma.j.issn.0254-6450.2017.03.008,,"Objective: To construct the air quality health index (AQHI) by inclusion of air pollutants PM(2.5) and O(3) in Guangzhou, Shanghai, Xi' an, Beijing, Shenyang, and explore scientificity and feasibility of its application in China. Methods: The daily average concentrations of PM(2.5) and O(3) in air, and daily average mortality from 2013 to 2015 in the 5 cities in China, the exposure-response coefficients of PM(2.5) and O(3) and total mortality from Meta studies in China were used to construct local AQHI. The health risk levels of air pollution in the 5 cities were calculated and compared with the characteristics of single pollutant concentrationof PM(2.5) or O(3). Results: In the 5 cities, the average concentration of PM(2.5) was highest in Beijing (82 mug/m(3)) and lowest in Guangzhou (46 mug/m(3)). And the average concentration of O(3) was highest in Shanghai (72 mug/m(3)) and lowest in Xi' an (45 mug/m(3)). In all the cities, the average concentration of PM(2.5) was highest in winter and lowest in summer. In summer, the average concentration of O(3) was lowest. But the health risk level of AQHI showed that the 5 cities had higher frequency of low or medium risk averagely. And Beijing had the highest frequency of high risk in summer (5.69%). Xi' an had the highest frequency of extremely high risk in winter (1.63%). Conclusions: In this study, AQHI could be constructed by using air PM(2.5) and O(3) concentration data which can be obtained in many areas in China. The application of this index is scientific and feasible in China.",10/03/2017,13/11/2018 10:47,14/04/2020 08:35,,314-319,,3,38,,Zhonghua Liu Xing Bing Xue Za Zhi,,,,,,,,chi,,,,,,,PMID: 28329931,,,,Humans; Reproducibility of Results; *Health Status; *Cities; China; Risk; Risk Assessment/methods; 00; Air pollution; PM(2.5); Environmental Monitoring; Air Pollutants/adverse effects/analysis; Air Pollution/adverse effects/*analysis; Environmental Exposure/adverse effects/*analysis; Health risk; Health status indicators; Ozone; Particulate Matter/adverse effects/*analysis; Seasons; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CXPDY63G,journalArticle,2017,"Passardi, Alessandro; Rizzo, Mimma; Maines, Francesca; Tondini, Carlo; Zambelli, Alberto; Vespignani, Roberto; Andreis, Daniele; Massa, Ilaria; Dianti, Marco; Forti, Stefano; Piras, Enrico Maria; Eccher, Claudio",Optimisation and validation of a remote monitoring system (Onco-TreC) for home-based management of oral anticancer therapies: an Italian multicentre feasibility study.,BMJ open,,2044-6055 2044-6055,10.1136/bmjopen-2016-014617,,"INTRODUCTION: Despite the growing number of oral agents available for cancer treatment, their efficacy may be reduced due to the lack of adherence, inappropriate adverse event self-management and arbitrary dose adjustment. The management of anticancer therapies could exponentially benefit from the introduction of mobile health technologies in a highly integrated electronic oncology system. METHODS AND ANALYSIS: We plan to customise and fine-tune an existing monitoring TreC platform used in different chronic diseases in the oncology setting. This project follows a multistep approach with two major purposes: 1. participatory design techniques driven by Health Literacy and Patient Reported Outcomes principles in order to adapt the system to the oncology setting involving patients and healthcare providers; 2. a prospective training-validation, interventional, non-pharmacological, multicentre study on a series of consecutive patients with cancer (20 and 60 patients in the training and validation steps, respectively) in order to assess system capability, usability and acceptability. The novel Onco-TreC 2.0 is expected to contribute to improving the adherence and safety of cancer care, promoting patient empowerment and patient-doctor communication. ETHICS AND DISSEMINATION: Ethical approval was obtained from the Independent Ethics Committees of the participating institutions (CEIIAV protocol Number 2549/2015; reference Number 1315-PU). Informed consent will be obtained from all study participants. Findings will be disseminated through peer-reviewed journals, conferences and event presentations. TRIAL REGISTRATION NUMBER: ClinicalTrials.gov (NCT02921724); (Pre-results). Other study ID Number: IRST100.18.",29/05/2017,13/11/2018 10:47,14/04/2020 08:35,,e014617,,5,7,,BMJ Open,,,,,,,,eng,(c) Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.,,,,,,PMID: 28554917 PMCID: PMC5729988,,,,"Humans; Physician-Patient Relations; Adult; Female; Male; Middle Aged; Young Adult; Aged; Adolescent; Aged, 80 and over; *Disease Management; Research Design; Feasibility Studies; *adherence; Self Administration; Administration, Oral; Italy; Neoplasms/drug therapy; Monitoring, Physiologic/*methods; *home-based healthcare management; *oral anticancer agents; *patient empowerment; *Patient Participation; *safety; Antineoplastic Agents/therapeutic use; Health Literacy; Telemedicine/*standards; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DM2UCM6R,journalArticle,2017,"Hvitfeldt-Forsberg, Helena; Mazzocato, Pamela; Glaser, Daniel; Keller, Christina; Unbeck, Maria",Staffs' and managers' perceptions of how and when discrete event simulation modelling can be used as a decision support in quality improvement: a focus group discussion study at two hospital settings in Sweden.,BMJ open,,2044-6055 2044-6055,10.1136/bmjopen-2016-013869,,"OBJECTIVE: To explore healthcare staffs' and managers' perceptions of how and when discrete event simulation modelling can be used as a decision support in improvement efforts. DESIGN: Two focus group discussions were performed. SETTING: Two settings were included: a rheumatology department and an orthopaedic section both situated in Sweden. PARTICIPANTS: Healthcare staff and managers (n=13) from the two settings. INTERVENTIONS: Two workshops were performed, one at each setting. Workshops were initiated by a short introduction to simulation modelling. Results from the respective simulation model were then presented and discussed in the following focus group discussion. RESULTS: Categories from the content analysis are presented according to the following research questions: how and when simulation modelling can assist healthcare improvement? Regarding how, the participants mentioned that simulation modelling could act as a tool for support and a way to visualise problems, potential solutions and their effects. Regarding when, simulation modelling could be used both locally and by management, as well as a pedagogical tool to develop and test innovative ideas and to involve everyone in the improvement work. CONCLUSIONS: Its potential as an information and communication tool and as an instrument for pedagogic work within healthcare improvement render a broader application and value of simulation modelling than previously reported.",06/06/2017,13/11/2018 10:47,14/04/2020 08:34,,e013869,,5,7,,BMJ Open,,,,,,,,eng,(c) Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.,,,,,,PMID: 28588107 PMCID: PMC5729970,,,,Humans; Focus Groups; *Decision Support Techniques; *emergency care; *focus group; *Health Personnel; *healthcare improvement; *orthopedic care; *Patient-Specific Modeling; *rheumatology; *Simulation modeling; Hospitals/*standards; Quality Improvement/*organization & administration; Sweden; 00; 100; 120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PQ8HKUMV,journalArticle,2017,"Telesmanich, Morgan E.; Jensen, Corey T.; Enriquez, Jose L.; Wagner-Bartak, Nicolaus A.; Liu, Xinming; Le, Ott; Wei, Wei; Chandler, Adam G.; Tamm, Eric P.",Third version of vendor-specific model-based iterativereconstruction (Veo 3.0): evaluation of CT image quality in the abdomen using new noise reduction presets and varied slice optimization.,The British journal of radiology,,1748-880X 0007-1285,10.1259/bjr.20170188,,"OBJECTIVE: To qualitatively and quantitatively compare abdominal CT images reconstructed with a newversion of model-based iterative reconstruction (Veo 3.0; GE Healthcare Waukesha, WI) utilizing varied presetsof resolution preference, noise reduction and slice optimization. METHODS: This retrospective study was approved by our Institutional Review Board and was Health Insurance Portability and Accountability Act compliant. The raw datafrom 30 consecutive patients who had undergone CT abdomen scanning were used to reconstructfour clinical presets of 3.75mm axial images using Veo 3.0: 5% resolution preference (RP05n), 5%noise reduction (NR05) and 40% noise reduction (NR40) with new 3.75mm ""sliceoptimization,"" as well as one set using RP05 with conventional 0.625mm ""slice optimization"" (RP05c). The images were reviewed by two independent readers in a blinded, randomized manner using a 5-point Likert scale as well as a 5-point comparative scale. Multiple two-dimensional circular regions of interest were defined for noise and contrast-to-noise ratio measurements. Line profiles were drawn across the 7 lp cm(-1) bar pattern of the Catphan 600 phantom for evaluation of spatial resolution. RESULTS: The NR05 image set was ranked as the best series in overall image quality (mean difference inrank 0.48, 95% CI [0.081-0.88], p = 0.01) and with specific reference to liver evaluation (meandifference 0.46, 95% CI [0.030-0.89], p = 0.03), when compared with the secondbest series ineach category. RP05n was ranked as the best for bone evaluation. NR40 was ranked assignificantly inferior across all assessed categories. Although the NR05 and RP05c image setshad nearly the same contrast-to-noise ratio and spatial resolution, NR05 was generally preferred. Image noise and spatial resolution increased along a spectrum with RP05n the highest and NR40the lowest. Compared to RP05n, the average noise was 21.01% lower for NR05, 26.88%lower for RP05c and 50.86% lower for NR40. CONCLUSION: Veo 3.0 clinical presets allow for selection of image noise and spatial resolution balance; for contrast-enhanced CT evaluation of the abdomen, the 5% noise reduction preset with 3.75 mm slice optimization (NR05) was generally ranked superior qualitatively and, relative to other series, was in the middle of the spectrum with reference to image noise and spatial resolution. Advances in knowledge: To our knowledge, this is the first study of Veo 3.0 noise reduction presets and varied slice optimization. This study provides insight into the behaviour of slice optimization and documents the degree of noise reduction and spatial resolution changes that users can expect across various Veo 3.0 clinical presets. These results provide important parameters to guide preset selection for both clinical and research purposes.",2017-08,13/11/2018 10:47,14/04/2020 08:35,,20170188,,1077,90,,Br J Radiol,,,,,,,,eng,,,,,,,PMID: 28707531 PMCID: PMC5858796,,,,"Humans; Adult; Female; Male; Middle Aged; Young Adult; Reproducibility of Results; Retrospective Studies; Evaluation Studies as Topic; 00; Image Processing, Computer-Assisted/*methods; Noise; Radiographic Image Interpretation, Computer-Assisted/*methods; Radiography, Abdominal/*methods; Signal-To-Noise Ratio; Tomography, X-Ray Computed/*methods; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3TLMYHY3,journalArticle,2017,"Henricksen, Jared W.; Altenburg, Catherine; Reeder, Ron W.",Operationalizing Healthcare Simulation Psychological Safety: A Descriptive Analysis of an Intervention.,Simulation in healthcare : journal of the Society for Simulation in Healthcare,,1559-713X 1559-2332,10.1097/SIH.0000000000000253,,"INTRODUCTION: Despite efforts to prepare a psychologically safe environment, simulation participants are occasionally psychologically distressed. Instructing simulation educators about participant psychological risks and having a participant psychological distress action plan available to simulation educators may assist them as they seek to keep all participants psychologically safe. METHODS: A Simulation Participant Psychological Safety Algorithm was designed to aid simulation educators as they debrief simulation participants perceived to have psychological distress and categorize these events as mild (level 1), moderate (level 2), or severe (level 3). A prebrief dedicated to creating a psychologically safe learning environment was held constant. The algorithm was used for 18 months in an active pediatric simulation program. Data collected included level of participant psychological distress as perceived and categorized by the simulation team using the algorithm, type of simulation that participants went through, who debriefed, and timing of when psychological distress was perceived to occur during the simulation session. The Kruskal-Wallis test was used to evaluate the relationship between events and simulation type, events and simulation educator team who debriefed, and timing of event during the simulation session. RESULTS: A total of 3900 participants went through 399 simulation sessions between August 1, 2014, and January 26, 2016. Thirty-four (<1%) simulation participants from 27 sessions (7%) were perceived to have an event. One participant was perceived to have a severe (level 3) psychological distress event. Events occurred more commonly in high-intensity simulations, with novice learners and with specific educator teams. Simulation type and simulation educator team were associated with occurrence of events (P < 0.001). There was no association between event timing and event level. CONCLUSIONS: Severe psychological distress as categorized by simulation personnel using the Simulation Participant Psychological Safety Algorithm is rare, with mild and moderate events being more common. The algorithm was used to teach simulation educators how to assist a participant who may be psychologically distressed and document perceived event severity.",2017-10,13/11/2018 10:47,14/04/2020 08:34,,289-297,,5,12,,Simul Healthc,,,,,,,,eng,,,,,,,PMID: 28976451,,,,"Humans; Female; Male; Interprofessional Relations; Algorithms; Formative Feedback; Patient Care Team; Severity of Illness Index; Simulation Training/*methods; 00; Health Personnel/*education/*psychology; Stress, Psychological/diagnosis/*prevention & control; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, P2AMBMVY,journalArticle,2017,"Brinks, Ralph; Hoyer, Annika; Rolka, Deborah B.; Kuss, Oliver; Gregg, Edward W.",Comparison of surveillance-based metrics for the assessment and monitoring of disease detection: simulation study about type 2 diabetes.,BMC medical research methodology,,1471-2288 1471-2288,10.1186/s12874-017-0328-2,,"BACKGROUND: Screening and detection of cases are a common public health priority for treatable chronic conditions with long subclinical periods. However, the validity of commonly-used metrics from surveillance systems for rates of detection (or case-finding) have not been evaluated. METHODS: Using data from a Danish diabetes register and a recently developed illness-death model of chronic diseases with subclinical conditions, we simulate two scenarios of different performance of case-finding. We report different epidemiological indices to assess case-finding in both scenarios and compare the validity of the results. RESULTS: The commonly used ratio of detected cases over total cases may lead to misleading conclusions. Instead, the ratio of undetected cases over persons without a diagnosis is a more valid index to distinguish the quality of case-finding. However, incidence-based measures are preferable to prevalence based indicators. CONCLUSION: Prevalence-based indices for assessing case-finding should be interpreted with caution. If possible, incidence-based indices should be preferred.",11/04/2017,13/11/2018 10:47,14/04/2020 08:34,,54,,1,17,,BMC Med Res Methodol,,,,,,,,eng,,,,,,,PMID: 28399821 PMCID: PMC5387346,,,,"Humans; Male; *Screening; *Diabetes; *Case-finding; *Chronic disease; *Compartment model; *Incidence; *Prevalence; *Undiagnosed disease; Chronic Disease/*epidemiology; Denmark/epidemiology; Diabetes Mellitus, Type 2/*diagnosis/*epidemiology; Mass Screening/*methods; 1; Markov; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7JJHRZMM,journalArticle,2017,"Espey, Eve; Baty, Gillian; Rask, John; Chungtuyco, Michelle; Pereda, Brenda; Leeman, Lawrence",Emergency in the clinic: a simulation curriculum to improve outpatient safety.,American journal of obstetrics and gynecology,,1097-6868 0002-9378,10.1016/j.ajog.2017.09.008,,"BACKGROUND: Emergency response skills are essential when events such as seizure, anaphylaxis, or hemorrhage occur in the outpatient setting. As services and procedures increasingly move outside the hospital, training to manage complications may improve outcomes. OBJECTIVE: The objective of this study was to evaluate a simulation-based curriculum in outpatient emergency management skills with the outcome measures of graded objective performance and learner self-efficacy. STUDY DESIGN: This pre- and postcurriculum study enrolled residents and fellows in Obstetrics and Gynecology and Family Medicine in a simulation-based, outpatient emergency management curriculum. Learners completed self-efficacy questionnaires and were videotaped managing 3 medical emergency scenarios (seizure, over-sedation/cardiopulmonary arrest, and hemorrhage) in the simulation laboratory both before and after completion of the curriculum. Evaluators who were blinded to training level scored the simulation performance videotapes using a graded rubric with critical action checklists. Scenario scores were assigned in 5 domains and globally. Paired t-tests were used to determine differences pre- and postcurriculum. RESULTS: Thirty residents completed the curriculum and pre- and postcurriculum testing. Subjects' objective performance scores improved in all 5 domains (P<.05) in all scenarios. When scores were stratified by level of training, all participants demonstrated global improvement. When scores were stratified by previous outpatient simulation experience, subjects with previous experience improved in all but management of excess sedation. Pre- and postcurriculum self-efficacy evaluations demonstrated improvement in all 7 measured areas: confidence, use of appropriate resources, communication skills, complex airway management, bag mask ventilation, resuscitation, and hemorrhage management. Self-efficacy assessment showed improvement in confidence managing outpatient emergencies (P=.001) and ability to communicate well in emergency situations (P<.001). CONCLUSION: A simulation-based curriculum improved both self-efficacy and objectively rated performance scores in management of outpatient medical emergencies. Simulation-based curricula should be incorporated into residency education.",2017-12,13/11/2018 10:47,14/04/2020 08:34,,699.e1-699.e13,,6,217,,Am J Obstet Gynecol,,,,,,,,eng,Copyright (c) 2017 Elsevier Inc. All rights reserved.,,,,,,PMID: 28919404,,,,"Humans; Disease Management; *Simulation Training; Female; Male; Patient Safety; Curriculum; Education, Medical, Graduate; Patient Care Team; Communication; Emergencies; Family Practice/*education; Heart Arrest/*therapy; Internship and Residency; Pregnancy; Resuscitation; 00; Obstetrics/*education; Cardiopulmonary Resuscitation; Self Efficacy; *Ambulatory Care; *emergency scenario; *outpatient; *patient safety; *simulation-based training; *women's health; Gynecology/*education; Hemorrhage/*therapy; Respiration, Artificial; Seizures/*therapy; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ICZ6JC3G,journalArticle,2017,"Oh, Taemin; Scheer, Justin K.; Smith, Justin S.; Hostin, Richard; Robinson, Chessie; Gum, Jeffrey L.; Schwab, Frank; Hart, Robert A.; Lafage, Virginie; Burton, Douglas C.; Bess, Shay; Protopsaltis, Themistocles; Klineberg, Eric O.; Shaffrey, Christopher I.; Ames, Christopher P.",Potential of predictive computer models for preoperative patient selection to enhance overall quality-adjusted life years gained at 2-year follow-up: a simulation in 234 patients with adult spinal deformity.,Neurosurgical focus,,1092-0684 1092-0684,10.3171/2017.9.FOCUS17494,,"OBJECTIVE Patients with adult spinal deformity (ASD) experience significant quality of life improvements after surgery. Treatment, however, is expensive and complication rates are high. Predictive analytics has the potential to use many variables to make accurate predictions in large data sets. A validated minimum clinically important difference (MCID) model has the potential to assist in patient selection, thereby improving outcomes and, potentially, cost-effectiveness. METHODS The present study was a retrospective analysis of a multiinstitutional database of patients with ASD. Inclusion criteria were as follows: age >/= 18 years, radiographic evidence of ASD, 2-year follow-up, and preoperative Oswestry Disability Index (ODI) > 15. Forty-six variables were used for model training: demographic data, radiographic parameters, surgical variables, and results on the health-related quality of life questionnaire. Patients were grouped as reaching a 2-year ODI MCID (+MCID) or not (-MCID). An ensemble of 5 different bootstrapped decision trees was constructed using the C5.0 algorithm. Internal validation was performed via 70:30 data split for training/testing. Model accuracy and area under the curve (AUC) were calculated. The mean quality-adjusted life years (QALYs) and QALYs gained at 2 years were calculated and discounted at 3.5% per year. The QALYs were compared between patients in the +MCID and -MCID groups. RESULTS A total of 234 patients met inclusion criteria (+MCID 129, -MCID 105). Sixty-nine patients (29.5%) were included for model testing. Predicted versus actual results were 50 versus 40 for +MCID and 19 versus 29 for -MCID (i.e., 10 patients were misclassified). Model accuracy was 85.5%, with 0.96 AUC. Predicted results showed that patients in the +MCID group had significantly greater 2-year mean QALYs (p = 0.0057) and QALYs gained (p = 0.0002). CONCLUSIONS A successful model with 85.5% accuracy and 0.96 AUC was constructed to predict which patients would reach ODI MCID. The patients in the +MCID group had significantly higher mean 2-year QALYs and QALYs gained. This study provides proof of concept for using predictive modeling techniques to optimize patient selection in complex spine surgery.",2017-12,13/11/2018 10:47,14/04/2020 08:35,,E2,,6,43,,Neurosurg Focus,,,,,,,,eng,,,,,,,PMID: 29191094,,,,Humans; Treatment Outcome; Adult; Female; Male; Middle Aged; *Quality-Adjusted Life Years; Aged; Follow-Up Studies; *Computer Simulation; Patient Selection; Quality of Life; Retrospective Studies; 00; ASD = adult spinal deformity; AUC = area under the curve; BMI = body mass index; Congenital Abnormalities/*surgery; Disability Evaluation; HRQOL = health-related QOL; IBF = interbody fusion; LIV = lowermost instrumented vertebra; MCID = minimum clinically important difference; minimum clinically important difference; NRS = numerical rating scale; ODI = Oswestry Disability Index; Oswestry Disability Index; predictive modeling; QALY = quality-adjusted life year; QOL = quality of life; quality-adjusted life year; Scoliosis/diagnosis/*surgery; SF-36 = 36-Item Short-Form Health Survey; Spinal Fusion/methods; SPO = Smith-Petersen osteotomy; SRS = Scoliosis Research Society; UIV = uppermost instrumented vertebra; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, K233HUVM,journalArticle,2017,"Yang, Yong",Using agent-based modeling to study multiple risk factors and multiple health outcomes at multiple levels.,Annals of the New York Academy of Sciences,,1749-6632 0077-8923,10.1111/nyas.13558,,"Most health studies focus on one health outcome and examine the influence of one or multiple risk factors. However, in reality, various pathways, interactions, and associations exist not only between risk factors and health outcomes but also among the risk factors and among health outcomes. The advance of system science methods, Big Data, and accumulated knowledge allows us to examine how multiple risk factors influence multiple health outcomes at multiple levels (termed a 3M study). Using the study of neighborhood environment and health as an example, I elaborate on the significance of 3M studies. 3M studies may lead to a significantly deeper understanding of the dynamic interactions among risk factors and outcomes and could help us design better interventions that may be of particular relevance for upstream interventions. Agent-based modeling (ABM) is a promising method in the 3M study, although its potentials are far from being fully explored. Future challenges include the gap of epidemiologic knowledge and evidence, lack of empirical data sources, and the technical challenges of ABM.",2017-11,13/11/2018 10:47,14/04/2020 08:35,,Jul-14,,1,1408,,Ann N Y Acad Sci,,,,,,,,eng,(c) 2017 New York Academy of Sciences.,,,,,,PMID: 29239482,,,,"Humans; Risk Factors; *agent-based modeling; *Diet; *Environment; *Health Status; *Models, Biological; *multiple levels; *multiple outcomes; *multiple risk factors; Diabetes Mellitus, Type 2/physiopathology; Exercise/*physiology; Obesity/physiopathology; Risk Assessment; agent-based modeling; 1; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GZQ3ZDMV,journalArticle,2018,"Paige, John T.; Terry Fairbanks, Rollin J.; Gaba, David M.",Priorities Related to Improving Healthcare Safety Through Simulation.,Simulation in healthcare : journal of the Society for Simulation in Healthcare,,1559-713X 1559-2332,10.1097/SIH.0000000000000295,,"STATEMENT: Improving healthcare safety is a worthwhile and important endeavor. Simulation-based activities can help with such a goal through research and training. In this manner, it can focus on education and training, assessment and metrics, process improvement, and culture change to help move forward both patient safety and quality of care.This article will address the following three main topics: (1) designing simulation-based activities to promote high reliability in healthcare, (2) developing simulation-based activities to foster resilience in healthcare systems, and (3) evaluating the impact of adverse events in healthcare and how simulation-based activities can be used to determine and potentially to prevent their cause. These topics will be treated sequentially, providing synopses of concepts and giving examples of research currently being undertaken. It will then highlight current priorities for simulation-based research in this domain by drawing from insights obtained and a targeted literature review.",2018-06,13/11/2018 10:47,14/04/2020 08:35,,S41-S50,,3S Suppl 1,13,,Simul Healthc,,,,,,,,eng,,,,,,,PMID: 29905627,,,,Humans; Medical Errors/prevention & control; Patient Care Team/organization & administration; Patient Safety; Reproducibility of Results; 00; *Organizational Culture; Health Occupations/*education; Inservice Training/organization & administration; Safety Management/*organization & administration/standards; Simulation Training/*organization & administration/standards; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, V6K9XUGJ,journalArticle,2018,"Goolsarran, Nirvani; Hamo, Carine E.; Lane, Susan; Frawley, Stacey; Lu, Wei-Hsin",Effectiveness of an interprofessional patient safety team-based learning simulation experience on healthcare professional trainees.,BMC medical education,,1472-6920 1472-6920,10.1186/s12909-018-1301-4,,"BACKGROUND: Although the American Council of Graduate Medical Education (ACGME) mandates formal education in patient safety, there is a lack of standardized educational practice on how to conduct patient safety training. Traditionally, patient safety is taught utilizing instructional strategies that promote passive learning such as self-directed online learning modules or didactic lectures that result in suboptimal learning and satisfaction. METHODS: During the summer of 2015, 76 trainees consisting of internal medicine interns and senior-level nursing students participated in an interactive patient safety workshop that used a flipped classroom approach integrating team based learning (TBL) and interprofessional simulated application exercises. RESULTS: Workshop trainees demonstrated an increase in knowledge specifically related to patient safety core concepts on the Team Readiness Assurance Test (TRAT) compared to the Individual Readiness Assurance Test (IRAT) (p = 0.001). Completion rates on the simulation application exercises checklists were high except for a few critical action items such as hand-washing, identifying barriers to care, and making efforts to clarify code status with patient. The Readiness for Interprofessional Learning Scale (RIPLS) subscale scores for Teamwork and Collaboration and Professional Identity were higher on the post-workshop survey compared to the pre-workshop survey, however only the difference in the Positive Professional Identity subscale was statistically significant (p = 0.03). A majority (90%) of the trainees either agreed that the safety concepts they learned would likely improve the quality of care they provide to future patients. CONCLUSIONS: This novel approach to safety training expanded teaching outside of the classroom and integrated simulation and engagement in error reduction strategies. Next steps include direct observation of trainees in the clinical setting for team-based competency when it comes to patient safety and recognition of system errors.",08/08/2018,13/11/2018 10:47,14/04/2020 08:34,,192,,1,18,,BMC Med Educ,,,,,,,,eng,,,,,,,PMID: 30089502 PMCID: PMC6083611,,,,"Humans; Learning; *Patient Simulation; Patient Safety/*standards; 00; Education, Medical/*standards; Checklist; Education, Nursing/*standards; Internal Medicine/education; Interprofessional education; Patient safety training; Simulation-based education; Students, Medical; Students, Nursing; Team-based learning; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7PMSZ34B,journalArticle,2017,"Sugiyama, Takehiro; Goryoda, Sayuri; Inoue, Kaori; Sugiyama-Ihana, Noriko; Nishi, Nobuo",Construction of a simulation model and evaluation of the effect of potential interventions on the incidence of diabetes and initiation of dialysis due to diabetic nephropathy in Japan.,BMC health services research,,1472-6963 1472-6963,10.1186/s12913-017-2784-0,,"BACKGROUND: The prevalence of diabetes mellitus is a growing public health concern in Japan. We developed a simulation model to predict the number of people with diabetes and those on dialysis due to diabetic nephropathy. In addition, we used the model to simulate the impact of possible interventions on the number of people with diabetes and those on dialysis due to diabetic nephropathy in the near future. METHODS: A simulation model with aging chains for diabetes management was built using system dynamics. The model was calibrated to population data from 2000 to 2015 (sex- and age category-specific population, the prevalence of diabetes, and the number of patients on dialysis due to diabetic nephropathy). We extrapolated the model up to 2035 in order to predict future prevalence of diabetes and related dialysis (base run). We also ran the model, hypothesizing that incidence of diabetes and/or related dialysis would be reduced by half from 2015 to 2025 and that this rate would be maintained until 2035, in order to investigate the effects of hypothetical interventions on future prevalence. RESULTS: The developed model forecasted the population with diabetes to increase until 2028 (5.58 million males and 3.34 million females), and the population on dialysis due to diabetic nephropathy to increase until 2035 (113,000 males and 48,000 females). Simulation experiments suggested that diabetes prevention interventions would decrease the number of patients on dialysis in 2035 by 13.8% in males and 12.6% in females compared to the base run. In contrast, interventions aiming to avoid dialysis initiation for patients with diabetes would decrease the number of patients on dialysis by 37.8% in males and 38.1% in females. CONCLUSIONS: We successfully developed a simulation model to project the number of patients with diabetes and those on dialysis due to diabetic nephropathy. Simulation experiments using the model suggested that, as far as the perspective of the next 20 years, intervention to prevent dialysis is an important means of bending the increasing curve of dialysis in the population with diabetes. Simulation analysis may be useful when making and evaluating health policies related to diabetes and other chronic diseases.",16/12/2017,13/11/2018 10:47,14/04/2020 08:34,,833,,1,17,,BMC Health Serv Res,,,,,,,,eng,,,,,,,PMID: 29246223 PMCID: PMC5732509,,,,"Humans; Forecasting; Adult; Female; Male; Middle Aged; Young Adult; Incidence; *Models, Theoretical; Cognition; System Dynamics; *Preventive Health Services; Diabetes mellitus; Diabetes Mellitus, Type 2/*epidemiology; Diabetic nephropathies; Diabetic Nephropathies/*epidemiology; Dialysis; Japan/epidemiology; Renal Dialysis/*trends; Systems analysis; 1; 220",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BTD44I6Z,journalArticle,2018,"Durham, Jo; Schubert, Lisa; Vaughan, Lisa; Willis, Cameron D.",Using systems thinking and the Intervention Level Framework to analyse public health planning for complex problems: Otitis media in Aboriginal and Torres Strait Islander children.,PloS one,,1932-6203 1932-6203,10.1371/journal.pone.0194275,,"BACKGROUND: Middle ear disease (otitis media) is endemic among Aboriginal and Torres Strait Islander children in Australia and represents an important cause of hearing loss. The disease is the result of a mix of biological, environmental and host risk factors that interact in complex, non-linear ways along a dynamic continuum. As such, it is generally recognised that a holistic, systems approach is required to reverse the high rates of otitis media in Aboriginal and Torres Strait Islander children. The objective of this paper is to examine the alignment between efforts designed to address otitis media in Aboriginal and Torres Strait Islander children in Queensland, Australia and core concepts of systems thinking. This paper's overall purpose is to identify which combination of activities, and at which level, hold the potential to facilitate systems changes to better support ear health among Aboriginal and Torres Strait Islander children. METHODS: We began with a review of documents identified in consultation with stakeholders and an online search. In addition, key informants were invited to participate in an online survey and a face-to-face or phone interview. Qualitative interviews using a semi-structured interview guide were used to explore survey responses in more depth. We also undertook interviews at the community level to elicit a diverse range of views. Ideas, statements or activities reported in the documents and interviews as being performed under the Intervention Level Framework were identified using qualitative thematic and content analysis. A quantitative descriptive analysis was also undertaken, whereby data was extracted into an Excel spreadsheet and coded under the relevant strategic directions and performance indicators of the Framework. Subsequently, we coded activities against the five-level intervention framework developed by Malhi and colleagues, that is: 1) paradigm; 2) goals; 3) system structure; 4) feedback and delays; and 5) structural elements. RESULTS: Overall, twenty documents were reviewed. We examined surveys and interviews with six key informants. Twenty-four individual and 3 group interviews were conducted across central and community level informants. One hundred and four items were coded from the 20 documents and 156 items from interview data. For both data sets, the majority of activities were coded at the structural elements level. The results suggested three key areas where further work is needed to drive sustained improvements: 1) build the governance structures needed for paradigm shift to achieve a multi-sectoral approach; 2) develop shared system level goals; 3) develop system-wide feedback processes. CONCLUSIONS: Sustained progress in improving ear health within Aboriginal and Torres Strait Islander children requires a holistic, system-wide approach. To advance such work, governance structures for multi-sectoral collaboration including the development of joint goals and monitoring and feedback are required. Intervening at these higher leverage points could have a profound effect on persistent public health issues.",2018,13/11/2018 10:47,14/04/2020 08:34,,e0194275,,3,13,,PLoS One,,,,,,,,eng,,,,,,,PMID: 29561891 PMCID: PMC5862467,,,,Humans; Surveys and Questionnaires; *Health Planning; *Oceanic Ancestry Group; *Public Health; *Public Health Surveillance; Australia/epidemiology/ethnology; Environment; Otitis Media/*epidemiology; Risk Factors; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TQQXVEFJ,journalArticle,2017,"Smith, Serenedy; Marino, Ingrid; Schaller, Jeanie; Arnell, Christopher; Moyes, Kelsey; Manley, Susan",Optimization of quality assurance to increase clinical utility and cost effectiveness of hereditary cancer testing.,Personalized medicine,,1741-0541 1741-0541,10.2217/pme-2016-0091,,"AIM: To evaluate one laboratory's hereditary cancer testing clinical quality assurance (QA) process to minimize test-ordering errors. METHODS: The proportion of tests canceled/revised due to pre-analytic QA processes or provider consultation prior to test ordering were determined and the resulting health cost savings were estimated. RESULTS: Over 2000 genetic test orders were canceled/revised over a 1-year period due to the laboratory QA process, saving US$5,801,832 in healthcare costs. Consultation with healthcare providers prior to submitting genetic test requests resulted in 37 canceled/revised test orders in a",2017-05,13/11/2018 10:47,14/04/2020 08:35,,213-220,,3,14,,Per Med,,,,,,,,eng,,,,,,,PMID: 29767585,,,,"Humans; Cost-Benefit Analysis; Health Care Costs; Laboratories; Quality Assurance, Health Care/*methods; 00; *clinical quality assurance process; *costs saved; *genetic testing; *healthcare costs; *healthcare providers; *hereditary breast and ovarian cancer; *Lynch syndrome; *test-ordering errors; Genetic Testing/*economics/methods; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YIQJZEZI,journalArticle,2013,"Weisshaar, Elke; Skudlik, Christoph; Scheidt, Reginald; Matterne, Uwe; Wulfhorst, Britta; Schonfeld, Michael; Elsner, Peter; Diepgen, Thomas L.; John, Swen M.",Multicentre study 'rehabilitation of occupational skin diseases -optimization and quality assurance of inpatient management (ROQ)'-results from 12-month follow-up.,Contact dermatitis,,1600-0536 0105-1873,10.1111/j.1600-0536.2012.02170.x,,"BACKGROUND: Occupational skin disease (OSD) is common, and imposes a considerable personal and public burden. To tackle OSD, the German stepwise procedure of handling OSD was set up. It contains an interdisciplinary, integrated inpatient rehabilitation measure [tertiary individual prevention (TIP)] [dermatological treatment and diagnostic procedures, and patient education (health and psychological)]. The primary aims of the TIP are reduction of the severity of OSD, reduction in the use of corticosteroids, facilitation of return to work, decreased absence from work, and enhanced quality of life (QoL). It was positively evaluated for a period of 4 weeks after return to work. OBJECTIVES: To investigate whether the observed short-term effects remain significant and meaningful over a period of 12 months after discharge from the TIP. METHODS: A prospective design was used to compare clinical and patient-reported outcome data between admission to a 3-week inpatient TIP and 12 months after discharge (12-month follow-up). RESULTS: Of 1788 individuals admitted to the TIP, data from 1617 individuals were available for analysis. We observed a significant reduction in the severity of OSD, the use of topical corticosteroids, and days of absence from work because of OSD. QoL was significantly improved, and 87.4% were able to return to work and remain in the workforce. CONCLUSIONS: A randomized controlled trial would have been desirable, but was not possible, for legal and other reasons. However, the long-term 12-month follow-up shows that the TIP is associated with sustained improvements in terms of ability to work, QoL, and prognosis, and reductions in days of absence from work because of skin conditions and topical corticosteroid application. These results indicate that the TIP provided a reduction in the personal and public burden of OSD.",2013-03,13/11/2018 10:47,14/04/2020 08:35,,169-174,,3,68,,Contact Dermatitis,,,,,,,,eng,(c) 2012 John Wiley & Sons A/S.,,,,,,PMID: 23046085,,,,"Humans; Program Evaluation; Treatment Outcome; Adult; Female; Male; Middle Aged; Quality of Life; Severity of Illness Index; Prospective Studies; Longitudinal Studies; Germany; Hospitalization; Quality Assurance, Health Care; 00; Absenteeism; Adrenal Cortex Hormones/therapeutic use; Dermatitis, Occupational/*rehabilitation; Tertiary Prevention; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2RPNV65E,journalArticle,2013,"Naik, Viren N.; Brien, Susan E.",Review article: simulation: a means to address and improve patient safety.,Canadian journal of anaesthesia = Journal canadien d'anesthesie,,1496-8975 0832-610X,10.1007/s12630-012-9860-z,,"PURPOSE: The purpose of this article is to review the role of technical and nontechnical skills in routine and crisis situations. We discuss the role of different simulation modalities in addressing these skills and competencies to enhance patient safety. PRINCIPAL FINDINGS: Human and system errors are a recognized cause of significant morbidity and mortality. Technical skills encompass the medical and procedural knowledge required for patient care, while nontechnical skills are behaviour-based and include task management, situation awareness, teamwork, decision-making, and leadership. Both sets of skills are required to improve patient safety. Healthcare simulation can provide an opportunity to practice technical and nontechnical skills in a patient-safe environment. More specifically, these skills are most required in dynamic and crisis situations, which may best be practiced in a simulated patient setting. CONCLUSION: Healthcare simulation is a valuable tool to improve patient safety. Simulation-based education can focus on the necessary technical and nontechnical skills to enhance patient safety. Simulation-based research can serve as a means to identify gaps in current practice, test different solutions, and show improved practice patterns by studying performance in a setting that does not compromise patient safety.",2013-02,13/11/2018 10:47,14/04/2020 08:35,,192-200,,2,60,,Can J Anaesth,,,,,,,,eng,,,,,,,PMID: 23239487,,,,Humans; Patient Care Team/organization & administration; Patient Safety; Decision Making; Computer Simulation; *Clinical Competence; Leadership; Medical Errors/*prevention & control; Patient Simulation; *Professional Competence; Delivery of Health Care/standards; Patient Care/standards; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, M8HJLKLY,journalArticle,2013,"Dolansky, Mary A.; Moore, Shirley M.",Quality and Safety Education for Nurses (QSEN): The Key is Systems Thinking.,Online journal of issues in nursing,,1091-3734 1091-3734,,,"Over a decade has passed since the Institute of Medicine's reports on the need to improve the American healthcare system, and yet only slight improvement in quality and safety has been reported. The Quality and Safety Education for Nurses (QSEN) initiative was developed to integrate quality and safety competencies into nursing education. The current challenge is for nurses to move beyond the application of QSEN competencies to individual patients and families and incorporate systems thinking in quality and safety education and healthcare delivery. This article provides a history of QSEN and proposes a framework in which systems thinking is a critical aspect in the application of the QSEN competencies. We provide examples of how using this framework expands nursing focus from individual care to care of the system and propose ways to teach and measure systems thinking. The conclusion calls for movement from personal effort and individual care to a focus on care of the system that will accelerate improvement of healthcare quality and safety.",30/09/2013,13/11/2018 10:47,14/04/2020 08:34,,1,,3,18,,Online J Issues Nurs,,,,,,,,eng,,,,,,,PMID: 26812094,,,,"Humans; *Quality of Health Care; United States; Clinical Competence; Patient Safety; Systems Analysis; 00; Education, Nursing/*standards; *Competency-Based Education; Safety Management; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, P42JA52V,journalArticle,2013,"Salas, Eduardo; Paige, John T.; Rosen, Michael A.",Creating new realities in healthcare: the status of simulation-based training as a patient safety improvement strategy.,BMJ quality & safety,,2044-5423 2044-5415,10.1136/bmjqs-2013-002112,,,2013-06,13/11/2018 10:47,14/04/2020 08:35,,449-452,,6,22,,BMJ Qual Saf,,,,,,,,eng,,,,,,,PMID: 23704117,,,,"Humans; Clinical Competence; *Patient Simulation; Medical Errors/prevention & control; Quality Assurance, Health Care/*methods; *Computer Simulation; Patient Care Team; Ambulatory Care; *Patient Safety/standards; Accreditation; Organizational Innovation; 00; *Inservice Training/methods/standards/trends; Adverse events, epidemiology and detection; Ambulatory care; Point-of-Care Systems; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RSW5HYTS,journalArticle,2013,"Ikkersheim, David; Tanke, Marit; van Schooten, Gwendy; de Bresser, Niels; Fleuren, Hein","Modeling hospital infrastructure by optimizing quality, accessibility and efficiency via a mixed integer programming model.",BMC health services research,,1472-6963 1472-6963,10.1186/1472-6963-13-220,,"BACKGROUND: The majority of curative health care is organized in hospitals. As in most other countries, the current 94 hospital locations in the Netherlands offer almost all treatments, ranging from rather basic to very complex care. Recent studies show that concentration of care can lead to substantial quality improvements for complex conditions and that dispersion of care for chronic conditions may increase quality of care. In previous studies on allocation of hospital infrastructure, the allocation is usually only based on accessibility and/or efficiency of hospital care. In this paper, we explore the possibilities to include a quality function in the objective function, to give global directions to how the 'optimal' hospital infrastructure would be in the Dutch context. METHODS: To create optimal societal value we have used a mathematical mixed integer programming (MIP) model that balances quality, efficiency and accessibility of care for 30 ICD-9 diagnosis groups. Typical aspects that are taken into account are the volume-outcome relationship, the maximum accepted travel times for diagnosis groups that may need emergency treatment and the minimum use of facilities. RESULTS: The optimal number of hospital locations per diagnosis group varies from 12-14 locations for diagnosis groups which have a strong volume-outcome relationship, such as neoplasms, to 150 locations for chronic diagnosis groups such as diabetes and chronic obstructive pulmonary disease (COPD). CONCLUSIONS: In conclusion, our study shows a new approach for allocating hospital infrastructure over a country or certain region that includes quality of care in relation to volume per provider that can be used in various countries or regions. In addition, our model shows that within the Dutch context chronic care may be too concentrated and complex and/or acute care may be too dispersed. Our approach can relatively easily be adopted towards other countries or regions and is very suitable to perform a 'what-if' analysis.",16/06/2013,13/11/2018 10:47,14/04/2020 08:34,,220,,,13,,BMC Health Serv Res,,,,,,,,eng,,,,,,,PMID: 23768234 PMCID: PMC3698106,,,,"Humans; Netherlands; Quality of Health Care; *Efficiency, Organizational; Computer Simulation; Models, Theoretical; Software; International Classification of Diseases; 00; *Total Quality Management; Chronic Disease/classification; Diagnosis-Related Groups/*statistics & numerical data; Health Services Accessibility/*standards; Hospitals, Special; Hospitals/*standards/statistics & numerical data; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MEPFZGRW,journalArticle,2012,"Boshuizen, Hendriek C.; Lhachimi, Stefan K.; van Baal, Pieter H. M.; Hoogenveen, Rudolf T.; Smit, Henriette A.; Mackenbach, Johan P.; Nusselder, Wilma J.",The DYNAMO-HIA model: an efficient implementation of a risk factor/chronic disease Markov model for use in Health Impact Assessment (HIA).,Demography,,0070-3370 0070-3370,10.1007/s13524-012-0122-z,,"In Health Impact Assessment (HIA), or priority-setting for health policy, effects of risk factors (exposures) on health need to be modeled, such as with a Markov model, in which exposure influences mortality and disease incidence rates. Because many risk factors are related to a variety of chronic diseases, these Markov models potentially contain a large number of states (risk factor and disease combinations), providing a challenge both technically (keeping down execution time and memory use) and practically (estimating the model parameters and retaining transparency). To meet this challenge, we propose an approach that combines micro-simulation of the exposure information with macro-simulation of the diseases and survival. This approach allows users to simulate exposure in detail while avoiding the need for large simulated populations because of the relative rareness of chronic disease events. Further efficiency is gained by splitting the disease state space into smaller spaces, each of which contains a cluster of diseases that is independent of the other clusters. The challenge of feasible input data requirements is met by including parameter calculation routines, which use marginal population data to estimate the transitions between states. As an illustration, we present the recently developed model DYNAMO-HIA (DYNAMIC MODEL for Health Impact Assessment) that implements this approach.",2012-11,13/11/2018 10:47,14/04/2020 08:34,,1259-1283,,4,49,,Demography,,,,,,,,eng,,,,,,,PMID: 23055232,,,,"Humans; Socioeconomic Factors; Adult; Female; Male; Middle Aged; Risk Factors; Aged; *Markov Chains; Aged, 80 and over; Incidence; Health Behavior; Diabetes Mellitus/epidemiology; Life Style; Smoking/epidemiology; Chronic Disease/*epidemiology/mortality; Health Impact Assessment/*methods/*statistics & numerical data; Obesity/epidemiology; 00; Review",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ZB3E5YCP,journalArticle,2012,"Kelly, Michelle; Jeffries, Pamela",Clinical simulation in health care--contemporary learning for safety and practice.,"Collegian (Royal College of Nursing, Australia)",,1322-7696 1322-7696,,,,2012,13/11/2018 10:47,14/04/2020 08:34,,115-116,,3,19,,Collegian,,,,,,,,eng,,,,,,,PMID: 23101344,,,,"Humans; Education, Professional/*methods; *Manikins; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ICD8RVPY,journalArticle,2013,"Willis, Michael; Asseburg, Christian; He, Jianming",Validation of economic and health outcomes simulation model of type 2 diabetes mellitus (ECHO-T2DM).,Journal of medical economics,,1941-837X 1369-6998,10.3111/13696998.2013.809352,,"OBJECTIVE: This study constructed the Economic and Health Outcomes Model for type 2 diabetes mellitus (ECHO-T2DM), a long-term stochastic microsimulation model, to predict the costs and health outcomes in patients with T2DM. Naturally, the usefulness of the model depends upon its predictive accuracy. The objective of this work is to present results of a formal validation exercise of ECHO-T2DM. METHODS: The validity of ECHO-T2DM was assessed using criteria recommended by the International Society for Pharmacoeconomics and Outcomes Research/Society for Medical Decision Making (ISPOR/SMDM). Specifically, the results of a number of clinical trials were predicted and compared with observed study end-points using a scatterplot and regression approach. An F-test of the best-fitting regression was added to assess whether it differs statistically from the identity (45 degrees ) line defining perfect predictions. In addition to testing the full model using all of the validation study data, tests were also performed of microvascular, macrovascular, and survival outcomes separately. The validation tests were also performed separately by type of data (used vs not used to construct the model, economic simulations, and treatment effects). RESULTS: The intercept and slope coefficients of the best-fitting regression line between the predicted outcomes and corresponding trial end-points in the main analysis were -0.0011 and 1.067, respectively, and the R(2) was 0.95. A formal F-test of no difference between the fitted line and the identity line could not be rejected (p = 0.16). The high R(2) confirms that the data points are closely (and linearly) associated with the fitted regression line. Additional analyses identified that disagreement was highest for macrovascular end-points, for which the intercept and slope coefficients were 0.0095 and 1.225, respectively. The R(2) was 0.95 and the estimated intercept and slope coefficients were 0.017 and 1.048, respectively, for mortality, and the F-test was narrowly rejected (p = 0.04). The sub-set of microvascular end-points showed some tendency to over-predict (the slope coefficient was 1.095), although concordance between predictions and observed values could not be rejected (p = 0.16). LIMITATIONS: Important study limitations include: (1) data availability limited one to tests based on end-of-study outcomes rather than time-varying outcomes during the studies analyzed; (2) complex inclusion and exclusion criteria in two studies were difficult to replicate; (3) some of the studies were older and reflect outdated treatment patterns; and (4) the authors were unable to identify published data on resource use and costs of T2DM suitable for testing the validity of the economic calculations. CONCLUSIONS: Using conventional methods, ECHO-T2DM simulated the treatment, progression, and patient outcomes observed in important clinical trials with an accuracy consistent with other well-accepted models. Macrovascular outcomes were over-predicted, which is common in health-economic models of diabetes (and may be related to a general over-prediction of event rates in the United Kingdom Prospective Diabetes Study [UKPDS] Outcomes Model). Work is underway in ECHO-T2DM to incorporate new risk equations to improve model prediction.",2013-08,13/11/2018 10:47,14/04/2020 08:35,,1007-1021,,8,16,,J Med Econ,,,,,,,,eng,,,,,,,PMID: 23718682,,,,"Humans; Cost-Benefit Analysis; Reproducibility of Results; *Models, Economic; Comorbidity; *Disease Progression; Blood Glucose; Blood Pressure; Body Mass Index; Diabetes Mellitus, Type 2/complications/*economics/*physiopathology; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WVNVN9NZ,journalArticle,2013,"Marques Sanchez, Pilar; Gonzalez Perez, Marta Eva; Agra Varela, Yolanda; Vega Nunez, Jorge; Pinto Carral, Arrate; Quiroga Sanchez, Enedina",[Social network analysis: a method to improve safety in healthcare organizations].,Revista espanola de salud publica,,2173-9110 1135-5727,10.4321/S1135-57272013000300001,,"Patient safety depends on the culture of the healthcare organization involving relationships between professionals. This article proposes that the study of these relations should be conducted from a network perspective and using a methodology called Social Network Analysis (SNA). This methodology includes a set of mathematical constructs grounded in Graph Theory. With the SNA we can know aspects of the individual's position in the network (centrality) or cohesion among team members. Thus, the SNA allows to know aspects related to security such as the kind of links that can increase commitment among professionals, how to build those links, which nodes have more prestige in the team in generating confidence or collaborative network, which professionals serve as intermediaries between the subgroups of a team to transmit information or smooth conflicts, etc. Useful aspects in stablishing a safety culture. The SNA would analyze the relations among professionals, their level of communication to communicate errors and spontaneously seek help and coordination between departments to participate in projects that enhance safety. Thus, they related through a network, using the same language, a fact that helps to build a culture. In summary, we propose an approach to safety culture from a SNA perspective that would complement other commonly used methods.",2013-06,13/11/2018 10:47,14/04/2020 08:34,,209-219,,3,87,,Rev Esp Salud Publica,,,,,,,,spa,,,,,,,PMID: 23892673,,,,Humans; Communication; *Patient Safety; *Interprofessional Relations; Patient Care Team/*organization & administration; *Social Support; Cooperative Behavior; Organizational Culture; 00; *Health Facilities; Risk Management/organization & administration; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GW3YV32X,journalArticle,2014,"Singh, Vishwajeet; Yadav, Rahul; Sinha, Rahul Janak; Gupta, Dheeraj Kumar",Prospective comparison of quality-of-life outcomes between ileal conduit urinary diversion and orthotopic neobladder reconstruction after radical cystectomy: a statistical model.,BJU international,,1464-410X 1464-4096,10.1111/bju.12440,,"OBJECTIVE: To conduct a prospective comparison of quality-of-life (QoL) outcomes in patients who underwent ileal conduit (IC) urinary diversion with those who underwent orthotopic neobladder (ONB) reconstruction after radical cystectomy for invasive bladder cancers. PATIENTS AND METHODS: Between January 2007 and December 2012, 227 patients underwent radical cystectomy and either IC urinary diversion or ONB (sigmoid or ileal) reconstruction. Contraindications for ON were impaired renal function (serum creatinine >2 mg/dL), chronic inflammatory bowel disease, previous bowel resection and tumour involvement at the bladder neck/prostatic urethra. Patients who did not have these contraindications chose to undergo either IC or ONB reconstruction, after impartial counselling. Baseline characteristics, including demographic profile, body mass index, comorbidities, histopathology of the cystoprostatectomy (with lymph nodes) specimen, pathological tumour stage, postoperative complications, adjuvant therapy and relapse, were recorded and compared. The European Organization for Research and Treatment of Cancer QoL questionnaire C30 version 3 was used to analyse QoL before surgery and 6, 12 and 18 months after surgery. RESULTS: Of the 227 patients, 28 patients in the IC group and 35 in the ONB group were excluded. The final analysis included 80 patients in the IC and 84 in the ONB group. None of the baseline characteristics were significantly different between the groups, except for age, but none of the baseline QoL variables were found to be correlated with age. In the preoperative phase, there were no significant differences in any of the QoL domains between the IC or the ONB groups. At 6, 12 and 18 months in the postoperative period, physical functioning (P < 0.001, P < 0.001 and P = 0.001, respectively), role functioning (P = 0.01, P = 0.01 and P = 0.003, respectively), social functioning (P = 0.01, P = 0.01 and P = 0.01, respectively) and global health status/QoL (P < 0.001, P < 0.001 and P = 0.002, respectively) were better in patients in the ONB group than in those in the IC group and the differences were significant. The financial burden related to bladder cancer treatment was significantly lower in the ONB group than in the IC group at 6, 12 and 18 months of follow-up (P = 0.05, P = 0.05 and P = 0.005, respectively) CONCLUSIONS: ONB is better than IC in terms of physical functioning, role functioning, social functioning, global health status/QoL and financial expenditure. ONB reconstruction provides better QoL outcomes than does IC urinary diversion.",2014-05,13/11/2018 10:47,14/04/2020 08:35,,726-732,,5,113,,BJU Int,,,,,,,,eng,(c) 2013 The Authors. BJU International (c) 2013 BJU International.,,,,,,PMID: 24053658,,,,"Humans; Surveys and Questionnaires; Treatment Outcome; Female; Male; Middle Aged; Follow-Up Studies; *Models, Statistical; *Health Status; Time Factors; Prospective Studies; *Quality of Life; quality of life; Postoperative Care; 00; bladder cancer; Cystectomy; ileal conduit; neobladder; radical cystectomy; Urinary Bladder Neoplasms/psychology/*surgery; Urinary Diversion/methods/*psychology; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BWCMXPAR,journalArticle,2015,"Lohaus, A.",[Stress Prevention in Adolescence: Evaluation and Optimisation of a Setting-Based Programme].,Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)),,1439-4421 0941-3790,10.1055/s-0032-1330035,,"The aim of the project was related to the development of a stress prevention programme for adolescents with a special focus on the use of the internet to communicate health-related topics. It could be shown that the evaluative programme effects were improved if a website was available in addition to a face-to-face training. This led to more positive results with regard to knowledge about stress and stress prevention, satisfaction with the training, symptom reduction and self-efficacy.",2015-09,13/11/2018 10:47,14/04/2020 08:34,,S68-69,,,77 Suppl 1,,Gesundheitswesen,,,,,,,,ger,(c) Georg Thieme Verlag KG Stuttgart . New York.,,,,,,PMID: 24081555,,,,"Humans; Program Evaluation; Treatment Outcome; Female; Male; Adolescent; Health Promotion/methods; Internet; Computer-Assisted Instruction/*methods; *Psychology, Adolescent; Adolescent Health; Health Education/*methods; Patient Education as Topic/methods; Preventive Medicine/*education/organization & administration; Stress, Psychological/*prevention & control/*psychology; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TTGHUCAQ,journalArticle,2013,"Mabry, Patricia L.; Milstein, Bobby; Abraido-Lanza, Ana F.; Livingood, William C.; Allegrante, John P.",Opening a window on systems science research in health promotion and public health.,Health education & behavior : the official publication of the Society for Public Health Education,,1552-6127 1090-1981,10.1177/1090198113503343,,,2013-10,13/11/2018 10:47,14/04/2020 08:34,,5S-8S,,1 Suppl,40,,Health Educ Behav,,,,,,,,eng,,,,,,,PMID: 24084401,,,,Humans; Systems Theory; 00; Health Promotion/methods/*organization & administration/standards; Health Services Research/methods/*organization & administration/standards; Public Health Administration/methods/*standards; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WDS7HJAB,journalArticle,2014,"Grant, Aileen M.; Guthrie, Bruce; Dreischulte, Tobias",Developing a complex intervention to improve prescribing safety in primary care: mixed methods feasibility and optimisation pilot study.,BMJ open,,2044-6055 2044-6055,10.1136/bmjopen-2013-004153,,"OBJECTIVES: (A) To measure the extent to which different candidate outcome measures identified high-risk prescribing that is potentially changeable by the data-driven quality improvement in primary care (DQIP) intervention.(B) To explore the value of reviewing identified high-risk prescribing to clinicians.(C) To optimise the components of the DQIP intervention. DESIGN: Mixed method study. SETTING: General practices in two Scottish Health boards. PARTICIPANTS: 4 purposively sampled general practices of varying size and socioeconomic deprivation. OUTCOME MEASURES: Prescribing measures targeting (1) high-risk use of the non-steroidal anti-inflammatory drugs (NSAIDs) and antiplatelets; (2) 'Asthma control' and (3) 'Antithrombotics in atrial fibrillation (AF)'. INTERVENTION: The prescribing measures were used to identify patients for review by general practices. The ability of the measures to identify potentially changeable high-risk prescribing was measured as the proportion of patients reviewed where practices identified a need for action. Field notes were recorded from meetings between researchers and staff and key staff participated in semistructured interviews exploring their experience of the piloted intervention processes. RESULTS: Practices identified a need for action in 68%, 25% and 18% of patients reviewed for prescribing measures (1), (2) and (3), respectively. General practitioners valued being prompted to review patients, and perceived that (1) 'NSAID and antiplatelet' and (2) 'antithrombotics in AF' were the most important to act on. Barriers to initial and ongoing engagement and to sustaining improvements in prescribing were identified. CONCLUSIONS: 'NSAIDs and antiplatelets' measures were selected as the most suitable outcome measures for the DQIP trial, based on evidence of this prescribing being more easily changeable. In response to the barriers identified, the intervention was designed to include a financial incentive, additional ongoing feedback on progress and reprompting review of patients, whose high-risk prescribing was restarted after a decision to stop. TRIAL REGISTRATION NUMBER: Clinicaltrials.gov NCT01425502.",21/01/2014,13/11/2018 10:47,14/04/2020 08:34,,e004153,,1,4,,BMJ Open,,,,,,,,eng,,,,,,,PMID: 24448848 PMCID: PMC3902335,,,,Humans; Drug Prescriptions/*standards; Pilot Projects; *Patient Safety; Quality Improvement; Feasibility Studies; *Primary Health Care; 1; Clinical Pharmacology; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LD2MVQJE,journalArticle,2014,"Muller-Leonhardt, Alice; Mitchell, Shannon G.; Vogt, Joachim; Schurmann, Tim",Critical Incident Stress Management (CISM) in complex systems: cultural adaptation and safety impacts in healthcare.,Accident; analysis and prevention,,1879-2057 0001-4575,10.1016/j.aap.2013.12.018,,"In complex systems, such as hospitals or air traffic control operations, critical incidents (CIs) are unavoidable. These incidents can not only become critical for victims but also for professionals working at the ""sharp end"" who may have to deal with critical incident stress (CIS) reactions that may be severe and impede emotional, physical, cognitive and social functioning. These CIS reactions may occur not only under exceptional conditions but also during every-day work and become an important safety issue. In contrast to air traffic management (ATM) operations in Europe, which have readily adopted critical incident stress management (CISM), most hospitals have not yet implemented comprehensive peer support programs. This survey was conducted in 2010 at the only European general hospital setting which implemented CISM program since 2004. The aim of the article is to describe possible contribution of CISM in hospital settings framed from the perspective of organizational safety and individual health for healthcare professionals. Findings affirm that daily work related incidents also can become critical for healthcare professionals. Program efficiency appears to be influenced by the professional culture, as well as organizational structure and policies. Overall, findings demonstrate that the adaptation of the CISM program in general hospitals takes time but, once established, it may serve as a mechanism for changing professional culture, thereby permitting the framing of even small incidents or near misses as an opportunity to provide valuable feedback to the system.",2014-07,13/11/2018 10:47,14/04/2020 08:35,,172-180,,,68,,Accid Anal Prev,,,,,,,,eng,Copyright (c) 2014 Elsevier Ltd. All rights reserved.,,,,,,PMID: 24491831,,,,"Humans; Adaptation, Psychological; Safety Management/*methods; Task Performance and Analysis; 00; *Organizational Culture; *Crisis Intervention; *Hospitals; Accidents, Occupational/*prevention & control; CISM program adaptation; Critical incident stress management (CISM); Critical incident stress reactions; Critical incidents in hospitals; Incidents in complex systems; Occupational Health Services/*organization & administration; Safety impacts; Stress Disorders, Post-Traumatic/prevention & control; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, X7DWHAZY,journalArticle,2014,"Souter, Caroline; Kinnear, Anne; Kinnear, Moira; Mead, Gillian","Optimisation of secondary prevention of stroke: a qualitative study of stroke patients' beliefs, concerns and difficulties with their medicines.",The International journal of pharmacy practice,,2042-7174 0961-7671,10.1111/ijpp.12104,,"OBJECTIVES: The objectives of this study are to explore stroke patients' and carers' beliefs and concerns about medicines and identify the barriers to medication adherence for secondary stroke prevention. METHODS: Qualitative semistructured one-on-one interviews were conducted with 30 patients with diagnosis of stroke. Interviews were analysed using the framework approach. KEY FINDINGS: The study suggests that stroke patients' and carers' perceptions of their medicines may influence medicine-taking behaviour. In some cases when beliefs outweighed concerns, practical barriers prevented participants taking their medicines. Negative beliefs about a medicine were strong enough to prevent some participants starting a new medicine. Participants' actions were influenced by the perceived consequences of not taking the medicine and the impact of the adverse effect on their quality of life. Concerns lessened with time with no adverse effects. The importance of the role of the carer and of a medicine-taking routine was evident. Participants reported the inadequacy of information provision and the desire to have more written and verbal information. Some reported total lack of contact with their general practitioner or community pharmacist after hospital discharge. CONCLUSIONS: Many of the difficulties stroke patients have adhering to secondary prevention strategies are potentially preventable with tailored information provision and appropriate monitoring and follow-up by primary healthcare professionals. We have designed an intervention addressing the identified barriers to medicine taking, the impact of which is currently being measured in a randomised controlled trial of a pharmacist-led home-based clinical medication review in stroke patients.",2014-12,13/11/2018 10:47,14/04/2020 08:35,,424-432,,6,22,,Int J Pharm Pract,,,,,,,,eng,(c) 2014 Royal Pharmaceutical Society.,,,,,,PMID: 24606322,,,,"Humans; Adult; Female; Male; Middle Aged; Aged; Aged, 80 and over; *Health Knowledge, Attitudes, Practice; *Medication Adherence; *Secondary Prevention; beliefs and concerns; Caregivers/psychology; medication taking behaviour; pharmacist; qualitative study; secondary prevention of stroke; Stroke/nursing/*prevention & control/*psychology; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, REVS3V4U,journalArticle,2014,"Eells, Samantha J.; Bharadwa, Kiran; McKinnell, James A.; Miller, Loren G.",Recurrent urinary tract infections among women: comparative effectiveness of 5 prevention and management strategies using a Markov chain Monte Carlo model.,Clinical infectious diseases : an official publication of the Infectious Diseases Society of America,,1537-6591 1058-4838,10.1093/cid/cit646,,"BACKGROUND: Recurrent urinary tract infections (UTIs) are a common problem among women. However, comparative effectiveness strategies for managing recurrent UTIs are lacking. METHODS: We performed a systematic literature review of management of women experiencing >/=3 UTIs per year. We then developed a Markov chain Monte Carlo model of recurrent UTI for each management strategy with >/=2 adequate trials published. We simulated a cohort that experienced 3 UTIs/year and a secondary cohort that experienced 8 UTIs/year. Model outcomes were treatment efficacy, patient and payer cost, and health-related quality of life. RESULTS: Five strategies had >/=2 clinical trials published: (1) daily antibiotic (nitrofurantoin) prophylaxis; (2) daily estrogen prophylaxis; (3) daily cranberry prophylaxis; (4) acupuncture prophylaxis; and (5) symptomatic self-treatment. In the 3 UTIs/year model, nitrofurantoin prophylaxis was most effective, reducing the UTI rate to 0.4 UTIs/year, and the most expensive to the payer ($821/year). All other strategies resulted in payer cost savings but were less efficacious. Symptomatic self-treatment was the only strategy that resulted in patient cost savings, and was the most favorable strategy in term of cost per quality-adjusted life-year (QALY) gained. CONCLUSIONS: Daily antibiotic use is the most effective strategy for recurrent UTI prevention compared to daily cranberry pills, daily estrogen therapy, and acupuncture. Cost savings to payers and patients were seen for most regimens, and improvement in QALYs were seen with all. Our findings provide clinically meaningful data to guide the physician-patient partnership in determining a preferred method of prevention for this common clinical problem.",2014-01,13/11/2018 10:47,14/04/2020 08:34,,147-160,,2,58,,Clin Infect Dis,,,,,,,,eng,,,,,,,PMID: 24065333 PMCID: PMC3871790,,,,Humans; Treatment Outcome; Health Care Costs; Female; Quality of Life; Health Expenditures; Recurrence; *Health Services Research; Acupuncture; Anti-Bacterial Agents/*therapeutic use; Estrogens/therapeutic use; management; recurrent; urinary tract infection; Urinary Tract Infections/*prevention & control/*therapy; Vaccinium macrocarpon; 00; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NAUP35M3,journalArticle,2013,"Sweeney, Patricia M.; Bjerke, Elizabeth F.; Guclu, Hasan; Keane, Christopher R.; Galvan, Jared; Gleason, Sherrianne M.; Potter, Margaret A.",Social network analysis: a novel approach to legal research on emergency public health systems.,Journal of public health management and practice : JPHMP,,1550-5022 1078-4659,10.1097/PHH.0b013e31829fc013,,,2013-12,13/11/2018 10:47,14/04/2020 08:35,,E38-40,,6,19,,J Public Health Manag Pract,,,,,,,,eng,,,,,,,PMID: 24080820 PMCID: PMC4012763,,,,Humans; United States; *Social Networking; *Research; *Disaster Planning; *Public Health Administration; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 29S5I8ZX,journalArticle,2013,"Ip, Edward H.; Rahmandad, Hazhir; Shoham, David A.; Hammond, Ross; Huang, Terry T.-K.; Wang, Youfa; Mabry, Patricia L.",Reconciling statistical and systems science approaches to public health.,Health education & behavior : the official publication of the Society for Public Health Education,,1552-6127 1090-1981,10.1177/1090198113493911,,"Although systems science has emerged as a set of innovative approaches to study complex phenomena, many topically focused researchers including clinicians and scientists working in public health are somewhat befuddled by this methodology that at times appears to be radically different from analytic methods, such as statistical modeling, to which the researchers are accustomed. There also appears to be conflicts between complex systems approaches and traditional statistical methodologies, both in terms of their underlying strategies and the languages they use. We argue that the conflicts are resolvable, and the sooner the better for the field. In this article, we show how statistical and systems science approaches can be reconciled, and how together they can advance solutions to complex problems. We do this by comparing the methods within a theoretical framework based on the work of population biologist Richard Levins. We present different types of models as representing different tradeoffs among the four desiderata of generality, realism, fit, and precision.",2013-10,13/11/2018 10:47,14/04/2020 08:34,,123S-31S,,1 Suppl,40,,Health Educ Behav,,,,,,,,eng,,,,,,,PMID: 24084395 PMCID: PMC5105232,,,,"Humans; *Models, Statistical; Child; complex systems; Data Interpretation, Statistical; Systems Theory; agent-based model; childhood obesity; computational model; Levins framework; Obesity/epidemiology/*prevention & control/therapy; Parent-Child Relations; Peer Group; Public Health/*methods/statistics & numerical data; social network analysis; Social Support; statistical model; system dynamics model; 1; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ABB3699V,journalArticle,2014,"Wilson, Andrew; Wutzke, Sonia; Overs, Marge",The Australian Prevention Partnership Centre: systems thinking to prevent lifestyle-related chronic illness.,Public health research & practice,,2204-2091 2204-2091,10.17061/phrp2511401,,"Chronic diseases are the major cause of death in Australia and the biggest contributor to premature death and disability. Although prevention of chronic disease can be effective and cost-effective, it has proven difficult to systematically implement interventions that target important lifestyle-related risk factors for chronic disease such as poor nutrition, physical inactivity and harmful alcohol use. Prevention efforts targeting these lifestyle-related risk factors have had mixed success due to issues around designing and implementing effective interventions that address the complexity of risk factors, and incorporating evidence and implementing interventions at a scale, duration, intensity and quality required to achieve population effects. There is increasing recognition that multilevel, multisector approaches are required for the effective and sustained prevention of complex chronic disease. The Australian Prevention Partnership Centre, one of two National Health and Medical Research Council Partnership Centres established in 2013, is researching and developing systems perspectives to prevent lifestyle-related chronic disease in Australia. The Centre's collaborative approach is providing opportunities for researchers to work with policy makers and practitioners to develop research questions, conduct research, and analyse, interpret and disseminate the findings. As such, it is the model of interaction that is being tested as much as the specific projects. With its funding partners, the Centre has developed plans for more than 30 projects. It has also established four capacity units that will improve the gathering, sharing and use of evidence to build a prevention system in Australia. The Centre is exploring new ways to advance prevention by bringing together researchers, policy makers and practitioners to determine the information and actions needed for an effective prevention system for Australia.",28/11/2014,13/11/2018 10:47,14/04/2020 08:35,,,,1,25,,Public Health Res Pract,,,,,,,,eng,,,,,,,PMID: 25828440,,,,"Humans; Middle Aged; Risk Factors; Systems Analysis; Models, Organizational; *Health Behavior; Australia/epidemiology; Interinstitutional Relations; *Social Determinants of Health; Capacity Building/methods/organization & administration; Cause of Death/trends; Chronic Disease/epidemiology/mortality/*prevention & control; Community-Institutional Relations; Comorbidity/trends; Disabled Persons/statistics & numerical data; Epidemiologic Research Design; Evidence-Based Medicine/methods/*standards; Food Supply/methods/standards; Health Plan Implementation/economics/*organization & administration/standards; Internationality; Outcome and Process Assessment (Health Care)/methods/organization & administration/standards; Preventive Health Services/methods/*organization & administration/standards; 1; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, F4C4MBDM,journalArticle,2014,"Costard, Solenne; Fournie, Guillaume; Pfeiffer, Dirk Udo",Using risk assessment as part of a systems approach to the control and prevention of HPAIV H5N1.,EcoHealth,,1612-9210 1612-9202,10.1007/s10393-014-0907-1,,"Since its emergence in China in 1996, highly pathogenic avian influenza virus subtype H5N1 has spread across Asia, Africa, and Europe. Countries had to promptly implement control and prevention measures. Numerous research and capacity building initiatives were conducted in the affected regions to improve the capacity of national animal health services to support the development of risk-based mitigation strategies. This paper reviews and discusses risk assessments initiated in several South-East Asian and African countries under one of these projects. Despite important data gaps, the risk assessment results improved the ability of policy makers to design appropriate risk management policies. Disease risk was strongly influenced by various human behavioral factors. The ongoing circulation of HPAIV H5N1 in several Asian countries and in Egypt, despite major disease control efforts, supports the need for an interdisciplinary approach to development of tailored risk management policies, in accordance with the EcoHealth paradigm and the broad concept of risk governance. In particular, active stakeholders engagement and integration of economic and social studies into the policy making process are needed to optimize compliance and sustainable behavioral changes, thereby increasing the effectiveness of mitigation strategies.",2014,13/11/2018 10:47,14/04/2020 08:34,,36-43,,1,11,,Ecohealth,,,,,,,,eng,,,,,,,PMID: 24488190,,,,"Humans; Risk Assessment/methods; Animals; Disease Outbreaks/*prevention & control; *International Cooperation; Africa/epidemiology; Asia, Southeastern/epidemiology; Birds; Global Health/*standards; Influenza A Virus, H5N1 Subtype; Influenza in Birds/*epidemiology/prevention & control; Influenza, Human/*epidemiology/prevention & control; Risk Management/*standards; 00; 100; 120",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PN3VDGBK,journalArticle,2014,"Goh, Yang Miang; Love, Peter; Dekker, Sidney",Editorial for special issue - 'systems thinking in workplace safety and health'.,Accident; analysis and prevention,,1879-2057 0001-4575,10.1016/j.aap.2014.02.005,,,2014-07,13/11/2018 10:47,14/04/2020 08:34,,01-Apr,,,68,,Accid Anal Prev,,,,,,,,eng,,,,,,,PMID: 24594087,,,,Humans; Systems Analysis; *Safety Management; Organizational Culture; *Systems Theory; 00; *Occupational Health; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 67URT2VB,journalArticle,2014,"Li, Yan; Kong, Nan; Lawley, Mark A.; Pagan, Jose A.",Using systems science for population health management in primary care.,Journal of primary care & community health,,2150-1327 2150-1319,10.1177/2150131914536400,,"OBJECTIVES: Population health management is becoming increasingly important to organizations managing and providing primary care services given ongoing changes in health care delivery and payment systems. The objective of this study is to show how systems science methodologies could be incorporated into population health management to compare different interventions and improve health outcomes. METHODS: The New York Academy of Medicine Cardiovascular Health Simulation model (an agent-based model) and data from the Behavioral Risk Factor Surveillance System were used to evaluate a lifestyle program that could be implemented in primary care practice settings. The program targeted Medicare-age adults and focused on improving diet and exercise and reducing weight. RESULTS: The simulation results suggest that there would be significant reductions projected in the proportion of the Medicare-age population with diabetes after the implementation of the proposed lifestyle program for a relatively long term (3 and 5 years). Similar results were found for the subpopulations with high cholesterol, but the proposed intervention would not have a significant effect in the proportion of the population with hypertension over a time period of <5 years. CONCLUSIONS: Systems science methodologies can be useful to compare the health outcomes of different interventions. These tools can become an important component of population health management because they can help managers and other decision makers evaluate alternative programs in primary care settings.",2014-10,13/11/2018 10:47,14/04/2020 08:34,,242-246,,4,5,,J Prim Care Community Health,,,,,,,,eng,(c) The Author(s) 2014.,,,,,,PMID: 24879655,,,,Delivery of Health Care/*organization & administration; Humans; Disease Management; Female; Male; Aged; Behavioral Risk Factor Surveillance System; systems science; Exercise; *Life Style; agent-based modeling; Diabetes Mellitus/prevention & control; Diet; Medicare; Overweight/prevention & control; population health management; primary care; Primary Health Care/*organization & administration; agent-based model; 1; 210,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HR53H3WC,journalArticle,2014,"Kassamali, Rahil H.; Kim, Daniel H.; Patel, Hiten; Raichura, Nitin; Hoey, Edward T. D.; Hodson, James; Hussain, Shahid",Safety of an i.v. beta-adrenergic blockade protocol for heart rate optimization before coronary CT angiography.,AJR. American journal of roentgenology,,1546-3141 0361-803X,10.2214/AJR.13.11492,,"OBJECTIVE: The purpose of this study was to assess the safety of heart rate optimization by use of beta-adrenergic blockade solely by the i.v. route before coronary CT angiography. MATERIALS AND METHODS: The records of 679 patients undergoing CT coronary angiography after receiving i.v. beta-adrenergic blockade were retrospectively analyzed. Health screening was completed before scanning, and heart rate was optimized by administration of i.v. metoprolol titrated to a maximum of 70 mg to achieve a heart rate less than 65 beats/min. RESULTS: The median i.v. dose was 20 mg (range, 5-70 mg). The 679 patients analyzed had a total of 10 complications (1.47%). Major complications, defined as not resolving with observation and analgesia alone, occurred in only three patients (0.44%). These complications included a second-degree atrioventricular block. A total of 299 patients (44.0%) needed more than 20 mg of i.v. metoprolol to achieve target heart rate. Only three patients needed the maximum i.v. dose of 70 mg metoprolol. Target heart rate was reached successfully in 666 patients (98.1%) with doses of less than 70 mg. This study did not show a statistically significant association between increasing complication frequency and increasing dose. CONCLUSION: This study showed that high doses of i.v. metoprolol can be used effectively and with a low rate of major complications to control heart rate before coronary CT angiography in correctly screened patients.",2014-10,13/11/2018 10:47,14/04/2020 08:34,,759-762,,4,203,,AJR Am J Roentgenol,,,,,,,,eng,,,,,,,PMID: 25247941,,,,"Humans; Treatment Outcome; Adult; Female; Male; Middle Aged; Young Adult; Patient Safety; Aged; Risk Assessment; Retrospective Studies; Adolescent; Aged, 80 and over; Dose-Response Relationship, Drug; safety; 00; Adrenergic beta-1 Receptor Antagonists/administration & dosage/adverse effects; Arrhythmias, Cardiac/*chemically induced/*prevention & control; beta-blockers; complications; Coronary Angiography/adverse effects/*methods; coronary CT angiography; Heart Rate/*drug effects; ischemic heart disease; metoprolol; Metoprolol/administration & dosage/*adverse effects; Premedication/adverse effects/*methods; side effects; Tomography, X-Ray Computed/adverse effects/*methods; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UZZ9IPLD,journalArticle,2014,"Hoppu, Sanna; Niemi-Murola, Leila; Handolin, Lauri",[Simulation training for better patient safety-learning from team work].,Duodecim; laaketieteellinen aikakauskirja,,0012-7183 0012-7183,,,"At work, healthcare personnel will encounter various emergency situations and patients who are in poor physical condition and require urgent care. A multidisciplinary team of experts must be able to carry out seamless collaboration, even when working together for the first time. Described in this review is how systematically arranged simulation rehearsals help form a united expert group from a group of individual experts.",2014,13/11/2018 10:47,14/04/2020 08:34,,1744-1748,,17,130,,Duodecim,,,,,,,,fin,,,,,,,PMID: 25272784,,,,"Humans; *Patient Safety; Patient Care Team/*organization & administration; Models, Organizational; Disaster Planning; Emergency Treatment/*methods; Planning Techniques; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UG4IXHHZ,journalArticle,2014,"Stephenson, Laurel S.; Gorsuch, Adriel; Hersh, William R.; Mohan, Vishnu; Gold, Jeffrey A.",Participation in EHR based simulation improves recognition of patient safety issues.,BMC medical education,,1472-6920 1472-6920,10.1186/1472-6920-14-224,,"BACKGROUND: Electronic health records (EHR) are becoming increasingly integrated into the clinical environment. With the rapid proliferation of EHRs, a number of studies document an increase in adverse patient safety issues due to the EHR-user interface. Because of these issues, greater attention has been placed on novel educational activities which incorporate use of the EHR. The ICU environment presents many challenges to integrating an EHR given the vast amounts of data recorded each day, which must be interpreted to deliver safe and effective care. We have used a novel EHR based simulation exercise to demonstrate that everyday users fail to recognize a majority of patient safety issues in the ICU. We now sought to determine whether participation in the simulation improves recognition of said issues. METHODS: Two ICU cases were created in our EHR simulation environment. Each case contained 14 safety issues, which differed in content but shared common themes. Residents were given 10 minutes to review a case followed by a presentation of management changes. Participants were given an immediate debriefing regarding missed issues and strategies for data gathering in the EHR. Repeated testing was performed in a cohort of subjects with the other case at least 1 week later. RESULTS: 116 subjects have been enrolled with 25 subjects undergoing repeat testing. There was no difference between cases in recognition of patient safety issues (39.5% vs. 39.4%). Baseline performance for subjects who participated in repeat testing was no different than the cohort as a whole. For both cases, recognition of safety issues was significantly higher among repeat participants compared to first time participants. Further, individual performance improved from 39.9% to 63.6% (p = 0.0002), a result independent of the order in which the cases were employed. The degree of improvement was inversely related to baseline performance. Further, repeat participants demonstrated a higher rate of recognition of changes in vitals, misdosing of antibiotics and oversedation compared to first time participants. CONCLUSION: Participation in EHR simulation improves EHR use and identification of patient safety issues.",21/10/2014,13/11/2018 10:47,14/04/2020 08:35,,224,,,14,,BMC Med Educ,,,,,,,,eng,,,,,,,PMID: 25336294 PMCID: PMC4287422,,,,Humans; Clinical Competence; Medical Errors/prevention & control; Cohort Studies; *Computer Simulation; Internship and Residency; *Patient Safety; *Computer-Assisted Instruction; *Electronic Health Records; *Intensive Care Units; Awareness; Oregon; 1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2X95V82V,journalArticle,2015,"McFadden, Emily; Stevens, Richard; Glasziou, Paul; Perera, Rafael",Implications of lower risk thresholds for statin treatment in primary prevention: analysis of CPRD and simulation modelling of annual cholesterol monitoring.,Preventive medicine,,1096-0260 0091-7435,10.1016/j.ypmed.2014.11.004,,"OBJECTIVE: To estimate numbers affected by a recent change in UK guidelines for statin use in primary prevention of cardiovascular disease. METHOD: We modelled cholesterol ratio over time using a sample of 45,151 men (>/=40years) and 36,168 women (>/=55years) in 2006, without statin treatment or previous cardiovascular disease, from the Clinical Practice Research Datalink. Using simulation methods, we estimated numbers indicated for new statin treatment, if cholesterol was measured annually and used in the QRISK2 CVD risk calculator, using the previous 20% and newly recommended 10% thresholds. RESULTS: We estimate that 58% of men and 55% of women would be indicated for treatment by five years and 71% of men and 73% of women by ten years using the 20% threshold. Using the proposed threshold of 10%, 84% of men and 90% of women would be indicated for treatment by 5years and 92% of men and 98% of women by ten years. CONCLUSION: The proposed change of risk threshold from 20% to 10% would result in the substantial majority of those recommended for cholesterol testing being indicated for statin treatment. Implications depend on the value of statins in those at low to medium risk, and whether there are harms.",2015-01,13/11/2018 10:47,14/04/2020 08:34,,14-16,,,70,,Prev Med,,,,,,,,eng,Copyright (c) 2014. Published by Elsevier Inc.,,,,,,PMID: 25445333 PMCID: PMC4295934,,,,"Humans; Adult; Female; Male; Middle Aged; Practice Guidelines as Topic; Comorbidity; Computer Simulation; United Kingdom; Diabetes Mellitus/epidemiology; Cardiovascular disease; Cardiovascular Diseases/epidemiology/*prevention & control; Cholesterol; Cholesterol, LDL/*blood; Epidemiological monitoring; Hydroxymethylglutaryl-CoA reductase inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & dosage/*standards; Primary health care; Primary Prevention/methods/*standards; Risk Assessment/methods/statistics & numerical data; Smoking/epidemiology; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, H3JDCF7X,journalArticle,2014,"Gomez-Cabrero, David; Lluch-Ariet, Magi; Tegner, Jesper; Cascante, Marta; Miralles, Felip; Roca, Josep",Synergy-COPD: a systems approach for understanding and managing chronic diseases.,Journal of translational medicine,,1479-5876 1479-5876,10.1186/1479-5876-12-S2-S2,,"Chronic diseases (CD) are generating a dramatic societal burden worldwide that is expected to persist over the next decades. The challenges posed by the epidemics of CD have triggered a novel health paradigm with major consequences on the traditional concept of disease and with a profound impact on key aspects of healthcare systems. We hypothesized that the development of a systems approach to understand CD together with the generation of an ecosystem to transfer the acquired knowledge into the novel healthcare scenario may contribute to a cost-effective enhancement of health outcomes. To this end, we designed the Synergy-COPD project wherein the heterogeneity of chronic obstructive pulmonary disease (COPD) was addressed as a use case representative of CD. The current manuscript describes main features of the project design and the strategies put in place for its development, as well the expected outcomes during the project life-span. Moreover, the manuscript serves as introductory and unifying chapter of the different papers associated to the Supplement describing the characteristics, tools and the objectives of Synergy-COPD.",28/11/2014,13/11/2018 10:47,14/04/2020 08:34,,S2,,,12 Suppl 2,,J Transl Med,,,,,,,,eng,,,,,,,PMID: 25472826 PMCID: PMC4255903,,,,"Humans; Delivery of Health Care; Program Development; Comorbidity; Computer Simulation; Electronic Health Records; Models, Organizational; *Decision Support Systems, Clinical; 1; Chronic Disease/therapy; Muscle, Skeletal/physiopathology; Pulmonary Disease, Chronic Obstructive/*physiopathology/*therapy; Telemedicine/methods; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HKMHQXQZ,journalArticle,2014,"Elsner, Peter; Aberer, Werner; Bauer, Andrea; Diepgen, Thomas Ludwig; Drexler, Hans; Fartasch, Manige; John, Swen Malte; Schuhmacher-Stock, Uta; Wehrmann, Wolfgang; Weisshaar, Elke",Cooperation between the occupational health insurance and physicians practicing occupational dermatology: optimization potential in quality assurance.,Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG,,1610-0387 1610-0379,10.1111/ddg.12348,,"BACKGROUND: Quality assurance is a task of the medical profession, but it is also a duty of the occupational health insurance (OHI). Data on the interaction quality between physicians practicing occupational dermatology and the OHI are limited. MATERIAL AND METHODS: An online survey was performed in 854 German members of the Working Group on Occupational and Environmental Dermatology in October 2013. Items included demographic data, a judgment on the cooperation between the dermatologists and OHI companies, an economic grading of the current compensation scheme, and prioritization of optimization tasks. RESULTS: 182 members (21.3 % of the invited population) participated in the survey. The cooperation with the OHI companies was judged as ""very good"" by 10.8 %, as ""good"" by 56.7 %, as ""satisfactory"" by 24.2 %, as ""sufficient"" by 7.0 % and as ""inadequate"" by 1.3 %. 93.4 % of the interviewed mentioned problems and improvement potentials in the cooperation of their practice or clinic with OHI companies. Main points of criticisms were reimbursement (44.7 %), followed by impairments of the treatment options (36.5 %) and the delay or scope of the treatment in the dermatologist's procedure (29.4 %). CONCLUSIONS: While most physicians practicing occupational dermatology give a positive judgment of their cooperation with OHI companies, quality optimization potentials exist regarding the reimbursement of dermatological services, especially regarding time-intensive counselling in the prevention of occupational skin diseases, in the enablement of diagnostic and therapeutic procedures according to current guidelines and in a timely preventive intervention to use the therapeutic window before chronification of skin diseases may occur.",2014-05,13/11/2018 10:47,14/04/2020 08:34,,408-414,,5,12,,J Dtsch Dermatol Ges,,,,,,,,eng,(c) 2014 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.,,,,,,PMID: 24797748,,,,"Humans; Health Services Research; Cost-Benefit Analysis; Female; Male; Middle Aged; *Cooperative Behavior; Attitude of Health Personnel; *Interdisciplinary Communication; Data Collection; Germany; Specialization; 1; *Dermatology/economics; *Health Benefit Plans, Employee/economics; *National Health Programs/economics; *Occupational Medicine/economics; *Quality Assurance, Health Care/economics; Dermatitis, Occupational/economics/*therapy; Hand Dermatoses/economics/*therapy; Workers' Compensation/economics; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VAVM6L9A,journalArticle,2014,"Mitsch, Christoph; Bolz, Matthias; Sacu, Stefan; Vass, Clemens; Scholda, Christoph; Huber, Patrick; Sabutsch, Stefan; Schmidt-Erfurth, Ursula",OphthalNet Vienna: constructive quality assurance and resource optimization in ophthalmology.,Studies in health technology and informatics,,0926-9630 0926-9630,,,"Significant improvements in the field of diagnostic methods and therapeutic options achieved during the last decade allow the early diagnosis, accurate follow-up and individual indication for the treatment with highly efficacious therapeutic agents in a wide range of ophthalmological pathologies. The burden on health care systems is extremely high, as treatment and diagnostic follow up has to be repeated in a regular manner. Whereas the treatment can only be applied in tertiary care centers (eye clinics), follow-up and management mainly depends on the OCT technology, which is becoming available at many field ophthalmologists' practices. This article describes the OphthalNet project, a network which optimizes collaboration between eye clinics and field ophthalmologists based on medical guidelines, workflow support and the future use of electronic infrastructure.",2014,13/11/2018 10:47,14/04/2020 08:34,,156-163,,,198,,Stud Health Technol Inform,,,,,,,,eng,,,,,,,PMID: 24825698,,,,"Humans; Efficiency, Organizational; Quality Assurance, Health Care/*organization & administration; Electronic Health Records/*organization & administration; 00; *Guidelines as Topic; Austria; Eye Diseases/*diagnosis/*therapy; Information Dissemination/methods; Ophthalmology/*organization & administration; Referral and Consultation/*organization & administration; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EIVWZQ48,journalArticle,2014,"Costello, Lee-Anne S.; Lithander, Fiona E.; Gruen, Russell L.; Williams, Lauren T.",Nutrition therapy in the optimisation of health outcomes in adult patients with moderate to severe traumatic brain injury: findings from a scoping review.,Injury,,1879-0267 0020-1383,10.1016/j.injury.2014.06.004,,"INTRODUCTION: Patients who have sustained traumatic brain injury (TBI) have increased nutritional requirements yet are often unable to eat normally, and adequate nutritional therapy is needed to optimise recovery. The aim of the current scoping review was to describe the existing evidence for improved outcomes with optimal nutrition therapy in adult patients with moderate to severe TBI, and to identify gaps in the literature to inform future research. METHODS: Using an exploratory scoping study approach, Medline, Cinahl, Embase, CENTRAL, the Neurotrauma reviews in the Global Evidence Mapping (GEM) Initiative, and Evidence Reviews in Acquired Brain Injury (ERABI) were searched from 2003 to 14 November 2013 using variations of the search terms 'traumatic brain injury' and 'nutrition'. Articles were included if they reported mortality, morbidity, or length of stay outcomes, and were classified according to the nature of nutrition intervention and study design. RESULTS: Twenty relevant articles were identified of which: 12 were original research articles; two were systematic reviews; one a meta-analysis; and five were narrative reviews. Of these, eleven explored timing of feed provision, eight explored route of administration of feeding, nine examined the provision of specific nutrients, and none examined feeding environment. Some explored more than one intervention. Three sets of guidelines which contain feeding recommendations were also identified. DISCUSSION: Inconsistency within nutrition intervention methods and outcome measures means that the present evidence base is inadequate for the construction of best practice guidelines for nutrition and TBI. Further research is necessary to elucidate the optimal nutrition therapy for adults with TBI with respect to the timing, route of administration, nutrient provision and feeding environment. A consensus on the ideal outcome measure and the most appropriate method and timing of its measurement is required as a foundation for this evidence base.",2014-12,13/11/2018 10:47,14/04/2020 08:34,,1834-1841,,12,45,,Injury,,,,,,,,eng,Copyright (c) 2014 Elsevier Ltd. All rights reserved.,,,,,,PMID: 24996574,,,,Humans; Treatment Outcome; Prognosis; Practice Guidelines as Topic; Time Factors; 00; *Nutrition Therapy/instrumentation/methods; Brain Injuries/complications/*therapy; Brain injury; Nutrition intervention; Trauma; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BYGBBRXN,journalArticle,2014,"Doi, Ryoichi; Pitiwut, Supachai",From maximization to optimization: a paradigm shift in rice production in Thailand to improve overall quality of life of stakeholders.,TheScientificWorldJournal,,1537-744X 1537-744X,10.1155/2014/604291,,"The concept of crop yield maximization has been widely supported. In practice, however, yield maximization does not necessarily lead to maximum socioeconomic welfare. Optimization is therefore necessary to ensure quality of life of farmers and other stakeholders. In Thailand, a rice farmers' network has adopted a promising agricultural system aimed at the optimization of rice farming. Various feasible techniques were flexibly combined. The new system offers technical strengths and minimizes certain difficulties with which the rice farmers once struggled. It has resulted in fairly good yields of up to 8.75 t ha(-1) or yield increases of up to 57% (from 4.38 to 6.88 t ha(-1)). Under the optimization paradigm, the farmers have established diversified sustainable relationships with the paddy fields in terms of ecosystem management through their own self-motivated scientific observations. The system has resulted in good health conditions for the farmers and villagers, financial security, availability of extra time, and additional opportunities and freedom and hence in the improvement of their overall quality of life. The underlying technical and social mechanisms are discussed herein.",2014,13/11/2018 10:47,14/04/2020 08:34,,604291,,,2014,,ScientificWorldJournal,,,,,,,,eng,,,,,,,PMID: 25089294 PMCID: PMC4099117,,,,Humans; Quality of Life; 00; *Agriculture; *Oryza; Thailand; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Y99BEQEZ,journalArticle,2014,"Fernandez, Maria E.; Melvin, Cathy L.; Leeman, Jennifer; Ribisl, Kurt M.; Allen, Jennifer D.; Kegler, Michelle C.; Bastani, Roshan; Ory, Marcia G.; Risendal, Betsy C.; Hannon, Peggy A.; Kreuter, Matthew W.; Hebert, James R.",The cancer prevention and control research network: An interactive systems approach to advancing cancer control implementation research and practice.,"Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology",,1538-7755 1055-9965,10.1158/1055-9965.EPI-14-0097,,"BACKGROUND: Although cancer research has advanced at a rapid pace, a gap remains between what is known about how to improve cancer prevention and control (CPC) and what is implemented as best practices within health care systems and communities. The Cancer Prevention and Control Research Network (CPCRN), with more than 10 years of dissemination and implementation research experience, aims to accelerate the uptake and use of evidence-based CPC interventions. METHODS: The collective work of the CPCRN has facilitated the analysis and categorization of research and implementation efforts according to the Interactive Systems Framework for Dissemination and Implementation (ISF), providing a useful heuristic for bridging the gap between prevention research and practice. The ISF authors have called for examples of its application as input to help refine the model. RESULTS: We provide examples of how the collaborative activities supported by the CPCRN, using community-engaged processes, accelerated the synthesis and translation of evidence, built both general and innovation-specific capacity, and worked with delivery systems to advance cancer control research and practice. CONCLUSIONS: The work of the CPCRN has provided real-world examples of the application of the ISF and demonstrated that synthesizing and translating evidence can increase the potential that evidence-based CPC programs will be used and that capacity building for both the support system and the delivery system is crucial for the successful implementation and maintenance of evidence-based cancer control. IMPACT: Adoption and implementation of CPC can be enhanced by better understanding ISF systems and intervening to improve them.",2014-11,13/11/2018 10:47,14/04/2020 08:34,,2512-2521,,11,23,,Cancer Epidemiol Biomarkers Prev,,,,,,,,eng,(c)2014 American Association for Cancer Research.,,,,,,PMID: 25155759 PMCID: PMC6013073,,,,Humans; *Research; Neoplasms/*prevention & control; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FTSB38BG,journalArticle,2014,"Laramee, Philippe; Brodtkorb, Thor-Henrik; Rahhali, Nora; Knight, Chris; Barbosa, Carolina; Francois, Clement; Toumi, Mondher; Daeppen, Jean-Bernard; Rehm, Jurgen",The cost-effectiveness and public health benefit of nalmefene added to psychosocial support for the reduction of alcohol consumption in alcohol-dependent patients with high/very high drinking risk levels: a Markov model.,BMJ open,,2044-6055 2044-6055,10.1136/bmjopen-2014-005376,,"OBJECTIVES: To determine whether nalmefene combined with psychosocial support is cost-effective compared with psychosocial support alone for reducing alcohol consumption in alcohol-dependent patients with high/very high drinking risk levels (DRLs) as defined by the WHO, and to evaluate the public health benefit of reducing harmful alcohol-attributable diseases, injuries and deaths. DESIGN: Decision modelling using Markov chains compared costs and effects over 5 years. SETTING: The analysis was from the perspective of the National Health Service (NHS) in England and Wales. PARTICIPANTS: The model considered the licensed population for nalmefene, specifically adults with both alcohol dependence and high/very high DRLs, who do not require immediate detoxification and who continue to have high/very high DRLs after initial assessment. DATA SOURCES: We modelled treatment effect using data from three clinical trials for nalmefene (ESENSE 1 (NCT00811720), ESENSE 2 (NCT00812461) and SENSE (NCT00811941)). Baseline characteristics of the model population, treatment resource utilisation and utilities were from these trials. We estimated the number of alcohol-attributable events occurring at different levels of alcohol consumption based on published epidemiological risk-relation studies. Health-related costs were from UK sources. MAIN OUTCOME MEASURES: We measured incremental cost per quality-adjusted life year (QALY) gained and number of alcohol-attributable harmful events avoided. RESULTS: Nalmefene in combination with psychosocial support had an incremental cost-effectiveness ratio (ICER) of pound5204 per QALY gained, and was therefore cost-effective at the pound20,000 per QALY gained decision threshold. Sensitivity analyses showed that the conclusion was robust. Nalmefene plus psychosocial support led to the avoidance of 7179 alcohol-attributable diseases/injuries and 309 deaths per 100,000 patients compared to psychosocial support alone over the course of 5 years. CONCLUSIONS: Nalmefene can be seen as a cost-effective treatment for alcohol dependence, with substantial public health benefits. TRIAL REGISTRATION NUMBERS: This cost-effectiveness analysis was developed based on data from three randomised clinical trials: ESENSE 1 (NCT00811720), ESENSE 2 (NCT00812461) and SENSE (NCT00811941).",16/09/2014,13/11/2018 10:47,14/04/2020 08:34,,e005376,,9,4,,BMJ Open,,,,,,,,eng,Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.,,,,,,PMID: 25227627 PMCID: PMC4166142,,,,Humans; Cost-Benefit Analysis; Female; Male; Middle Aged; *Public Health; Markov Chains; Risk Assessment; *Social Support; Cost-effectiveness; QALY; Alcohol dependence; Alcohol Drinking/*economics/*prevention & control; Alcoholism/*drug therapy; Combined Modality Therapy/*economics; Cost-utility; Economic analysis; Nalmefene; Naltrexone/*analogs & derivatives/economics/therapeutic use; 00; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9Q4KRPMD,journalArticle,2014,"Yaylali, Emine; Ivy, Julie Simmons; Taheri, Javad","Systems engineering methods for enhancing the value stream in public health preparedness: the role of Markov models, simulation, and optimization.","Public health reports (Washington, D.C. : 1974)",,1468-2877 0033-3549,10.1177/00333549141296S419,,"OBJECTIVES: Large-scale incidents such as the 2009 H1N1 outbreak, the 2011 European Escherichia coli outbreak, and Hurricane Sandy demonstrate the need for continuous improvement in emergency preparation, alert, and response systems globally. As questions relating to emergency preparedness and response continue to rise to the forefront, the field of industrial and systems engineering (ISE) emerges, as it provides sophisticated techniques that have the ability to model the system, simulate, and optimize complex systems, even under uncertainty. METHODS: We applied three ISE techniques--Markov modeling, operations research (OR) or optimization, and computer simulation--to public health emergency preparedness. RESULTS: We present three models developed through a four-year partnership with stakeholders from state and local public health for effectively, efficiently, and appropriately responding to potential public health threats: (1) an OR model for optimal alerting in response to a public health event, (2) simulation models developed to respond to communicable disease events from the perspective of public health, and (3) simulation models for implementing pandemic influenza vaccination clinics representative of clinics in operation for the",2014,13/11/2018 10:47,14/04/2020 08:34,,145-153,,,129 Suppl 4,,Public Health Rep,,,,,,,,eng,,,,,,,PMID: 25355986 PMCID: PMC4187318,,,,"Humans; *Quality Improvement; Markov Chains; *Computer Simulation; *Operations Research; *Public Health Practice; Disease Outbreaks/prevention & control; Models, Organizational; Disaster Planning/*organization & administration/standards; Influenza, Human/prevention & control; 1; Markov; 420",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NUFVAMZ9,journalArticle,2015,"Shahdoust, Maryam; Sadeghifar, Majid; Poorolajal, Jalal; Javanrooh, Niloofar; Amini, Payam",Predicting hepatitis B monthly incidence rates using weighted Markov chains and time series methods.,Journal of research in health sciences,,2228-7809 2228-7795,,,"BACKGROUND: Hepatitis B (HB) is a major global mortality. Accurately predicting the trend of the disease can provide an appropriate view to make health policy disease prevention. This paper aimed to apply three different to predict monthly incidence rates of HB. METHODS: This historical cohort study was conducted on the HB incidence data of Hamadan Province, the west of Iran, from 2004 to 2012. Weighted Markov Chain (WMC) method based on Markov chain theory and two time series models including Holt Exponential Smoothing (HES) and SARIMA were applied on the data. The results of different applied methods were compared to correct percentages of predicted incidence rates. RESULTS: The monthly incidence rates were clustered into two clusters as state of Markov chain. The correct predicted percentage of the first and second clusters for WMC, HES and SARIMA methods was (100, 0), (84, 67) and (79, 47) respectively. CONCLUSIONS: The overall incidence rate of HBV is estimated to decrease over time. The comparison of results of the three models indicated that in respect to existing seasonality trend and non-stationarity, the HES had the most accurate prediction of the incidence rates.",2015,13/11/2018 10:47,14/04/2020 08:35,,28-31,,1,15,,J Res Health Sci,,,,,,,,eng,,,,,,,PMID: 25821022,,,,"Humans; Adult; Female; Male; Cohort Studies; Markov Chains; *Models, Statistical; Incidence; Hepatitis B; Hepatitis B/*epidemiology; Incidence rate; Iran/epidemiology; Prediction; Time series; 1; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6LDQ3VSD,journalArticle,2017,"Botsis, Taxiarchis; Foster, Matthew; Arya, Nina; Kreimeyer, Kory; Pandey, Abhishek; Arya, Deepa",Application of Natural Language Processing and Network Analysis Techniques to Post-market Reports for the Evaluation of Dose-related Anti-Thymocyte Globulin Safety Patterns.,Applied clinical informatics,,1869-0327 1869-0327,10.4338/ACI-2016-10-RA-0169,,"OBJECTIVE: To evaluate the feasibility of automated dose and adverse event information retrieval in supporting the identification of safety patterns. METHODS: We extracted all rabbit Anti-Thymocyte Globulin (rATG) reports submitted to the United States Food and Drug Administration Adverse Event Reporting System (FAERS) from the product's initial licensure in April 16, 1984 through February 8, 2016. We processed the narratives using the Medication Extraction (MedEx) and the Event-based Text-mining of Health Electronic Records (ETHER) systems and retrieved the appropriate medication, clinical, and temporal information. When necessary, the extracted information was manually curated. This process resulted in a high quality dataset that was analyzed with the Pattern-based and Advanced Network Analyzer for Clinical Evaluation and Assessment (PANACEA) to explore the association of rATG dosing with post-transplant lymphoproliferative disorder (PTLD). RESULTS: Although manual curation was necessary to improve the data quality, MedEx and ETHER supported the extraction of the appropriate information. We created a final dataset of 1,380 cases with complete information for rATG dosing and date of administration. Analysis in PANACEA found that PTLD was associated with cumulative doses of rATG >8 mg/kg, even in periods where most of the submissions to FAERS reported low doses of rATG. CONCLUSION: We demonstrated the feasibility of investigating a dose-related safety pattern for a particular product in FAERS using a set of automated tools.",26/04/2017,13/11/2018 10:47,14/04/2020 08:34,,396-411,,2,8,,Appl Clin Inform,,,,,,,,eng,,,,,,,PMID: 28447098,,,,"Humans; *Safety; Time Factors; Dose-Response Relationship, Drug; Feasibility Studies; 00; *Adverse Drug Reaction Reporting Systems; *data visualization; *information retrieval; *Natural language processing; *Natural Language Processing; *network analysis; *postmarketing product surveillance; Antilymphocyte Serum/*adverse effects; Data Mining/*methods; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VVE2EE4P,journalArticle,2016,"Velazquez-Martinez, J. D.; Cruz-Suarez, H.; Santos-Reyes, J.",[Analysis and modelling of safety culture in a Mexican hospital by Markov chains].,Revista de calidad asistencial : organo de la Sociedad Espanola de Calidad Asistencial,,1887-1364 1134-282X,10.1016/j.cali.2016.03.001,,"INTRODUCTION: The objective of this study was to analyse and model the safety culture with Markov chains, as well as predicting and/or prioritizing over time the evolutionary behaviour of the safety culture of the health's staff in one Mexican hospital. METHOD: The Markov chain theory has been employed in the analysis, and the input data has been obtained from a previous study based on the Safety Attitude Questionnaire (CAS-MX-II), by considering the following 6 dimensions: safety climate, teamwork, job satisfaction, recognition of stress, perception of management, and work environment. RESULTS: The results highlighted the predictions and/or prioritisation of the approximate time for the possible integration into the evolutionary behaviour of the safety culture as regards the ""slightly agree"" (Likert scale) for: safety climate (in 12 years; 24.13%); teamwork (8 years; 34.61%); job satisfaction (11 years; 52.41%); recognition of the level of stress (8 years; 19.35%); and perception of the direction (22 years; 27.87%). The work environment dimension was unable to determine the behaviour of staff information, i.e. no information cultural roots were obtained. CONCLUSION: In general, it has been shown that there are weaknesses in the safety culture of the hospital, which is an opportunity to suggest changes to the mandatory policies in order to strengthen it.",2016-10,13/11/2018 10:47,14/04/2020 08:34,,309-314,,5,31,,Rev Calid Asist,,,,,,,,spa,"Copyright (c) 2016 SECA. Publicado por Elsevier Espana, S.L.U. All rights reserved.",,,,,,PMID: 27084297,,,,Humans; Surveys and Questionnaires; Mexico; *Markov Chains; *Patient Safety; *Safety Management; Attitude of Health Personnel; Hospitals; Job Satisfaction; Markov chain; Safety culture; 1; *Organizational Culture; Cadenas de Markov; Cuestionario de actitudes seguras; Cultura de seguridad; Health services; Safety attitude questionnaire; Sector salud; 320,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RFQWHKNP,journalArticle,2014,"Bas, Esra",An integrated quality function deployment and capital budgeting methodology for occupational safety and health as a systems thinking approach: the case of the construction industry.,Accident; analysis and prevention,,1879-2057 0001-4575,10.1016/j.aap.2013.10.005,,"In this paper, an integrated methodology for Quality Function Deployment (QFD) and a 0-1 knapsack model is proposed for occupational safety and health as a systems thinking approach. The House of Quality (HoQ) in QFD methodology is a systematic tool to consider the inter-relationships between two factors. In this paper, three HoQs are used to consider the interrelationships between tasks and hazards, hazards and events, and events and preventive/protective measures. The final priority weights of events are defined by considering their project-specific preliminary weights, probability of occurrence, and effects on the victim and the company. The priority weights of the preventive/protective measures obtained in the last HoQ are fed into a 0-1 knapsack model for the investment decision. Then, the selected preventive/protective measures can be adapted to the task design. The proposed step-by-step methodology can be applied to any stage of a project to design the workplace for occupational safety and health, and continuous improvement for safety is endorsed by the closed loop characteristic of the integrated methodology.",2014-07,13/11/2018 10:47,14/04/2020 08:34,,42-56,,,68,,Accid Anal Prev,,,,,,,,eng,Copyright (c) 2013 Elsevier Ltd. All rights reserved.,,,,,,PMID: 24188741,,,,"Humans; Budgets; *Systems Analysis; *Models, Organizational; Organizational Case Studies; Safety Management/economics/*methods; 00; *Construction Industry; *Occupational Health; Accidents, Occupational/*prevention & control; 0-1 Knapsack model; Accident cost; Construction; Injury severity score; Injury Severity Score; Quality Control; Quality function deployment; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FH53HXZK,journalArticle,2018,"Wong, Ambrose H.; Auerbach, Marc A.; Ruppel, Halley; Crispino, Lauren J.; Rosenberg, Alana; Iennaco, Joanne D.; Vaca, Federico E.",Addressing Dual Patient and Staff Safety Through A Team-Based Standardized Patient Simulation for Agitation Management in the Emergency Department.,Simulation in healthcare : journal of the Society for Simulation in Healthcare,,1559-713X 1559-2332,10.1097/SIH.0000000000000309,,"INTRODUCTION: Emergency departments (EDs) have seen harm rise for both patients and health workers from an increasing rate of agitation events. Team effectiveness during care of this population is particularly challenging because fear of physical harm leads to competing interests. Simulation is frequently employed to improve teamwork in medical resuscitations but has not yet been reported to address team-based behavioral emergency care. As part of a larger investigation of agitated patient care, we designed this secondary study to examine the impact of an interprofessional standardized patient simulation for ED agitation management. METHODS: We used a mixed-methods approach with emergency medicine resident and attending physicians, Physician Assistants (PAs) and Advanced Practice Registered Nurses (APRNs), ED nurses, technicians, and security officers at two hospital sites. After a simulated agitated patient encounter, we conducted uniprofessional and interprofessional focus groups. We undertook structured thematic analysis using a grounded theory approach. Quantitative data consisted of responses to the KidSIM Questionnaire addressing teamwork and simulation-based learning attitudes before and after each session. RESULTS: We reached data saturation with 57 participants. KidSIM scores revealed significant improvements in attitudes toward relevance of simulation, opportunities for interprofessional education, and situation awareness, as well as four of six questions for roles/responsibilities. Two broad themes emerged from the focus groups: (1) a team-based agitated patient simulation addressed dual safety of staff and patients simultaneously and (2) the experience fostered interprofessional discovery and cooperation in agitation management. CONCLUSIONS: A team-based simulated agitated patient encounter highlighted the need to consider the dual safety of staff and patients while facilitating interprofessional dialog and learning. Our findings suggest that simulation may be effective to enhance teamwork in behavioral emergency care.",2018-06,13/11/2018 10:47,14/04/2020 08:35,,154-162,,3,13,,Simul Healthc,,,,,,,,eng,,,,,,,PMID: 29613919,,,,"Humans; *Patient Simulation; Patient Care Team/organization & administration; Patient Safety; Academic Medical Centers; Emergency Service, Hospital/*organization & administration; Health Personnel/education; Interprofessional Relations; Professional Role; Safety Management/*organization & administration; 00; *Aggression; Personnel, Hospital/*education; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QYEJMALF,journalArticle,2013,"Vil'k, M. F.; Korotich, L. P.; Polyakova, V.",[A scientific providing for the system of hygienic optimization and anti-epidemic safety of rail ridership].,Gigiena i sanitariia,,0016-9900 0016-9900,,,"The system of scientific and reasonable measures for hygienic and anti-epidemic providing of rail ridership is elaborated. The legal and methodical base for precautionary and current sanitary inspection in the field of hygiene and epidemiology of ridership has been created, standard and methodical documents have been introduced in practice of medical sanitary health services of the railroads and accepted to realization by the design, car-building and car-repair organizations. Sanitary and hygienic monitoring for rail ridership, including control for sanitary, hygienic and microbiological indices of the air environment of passenger and service premises of stations and passenger trains, and also control for indices of health of the workers providing ridership, with use of pre-nosological symptoms of pathology is organized. Features of a bacterial aero-plankton of passenger objects are revealed. The increase of indices of bacterial pollution of air in passenger objects during the summer-autumn periods of year in comparison with winter period is established. Direct relationship between levels of bacterial air pollution of passenger rooms of stations and integrated indices of anti-infectious stability of an organism of workers of the railway stations serving ridership, and also number of persons with the changed indices of the immune status is revealed.",2013-02,13/11/2018 10:47,14/04/2020 08:35,,26-29,,1,,,Gig Sanit,,,,,,,,rus,,,,,,,PMID: 23805688,,,,"Humans; Russia/epidemiology; 00; *Hygiene; *Railroads; Air Microbiology; Air Pollution, Indoor/*prevention & control; Bacterial Infections/epidemiology/prevention & control; Environmental Exposure/prevention & control; Environmental Monitoring/methods; Occupational Exposure/*prevention & control; Occupational Health; Sanitation/methods; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BPMQMK5R,journalArticle,2014,"Yeung, Joyce; Davies, Robin; Gao, Fang; Perkins, Gavin D.",A randomised control trial of prompt and feedback devices and their impact on quality of chest compressions--a simulation study.,Resuscitation,,1873-1570 0300-9572,10.1016/j.resuscitation.2014.01.015,,"AIM: This study aims to compare the effect of three CPR prompt and feedback devices on quality of chest compressions amongst healthcare providers. METHODS: A single blinded, randomised controlled trial compared a pressure sensor/metronome device (CPREzy), an accelerometer device (Phillips Q-CPR) and simple metronome on the quality of chest compressions on a manikin by trained rescuers. The primary outcome was compression depth. Secondary outcomes were compression rate, proportion of chest compressions with inadequate depth, incomplete release and user satisfaction. RESULTS: The pressure sensor device improved compression depth (37.24-43.64 mm, p=0.02), the accelerometer device decreased chest compression depth (37.38-33.19 mm, p=0.04) whilst the metronome had no effect (39.88 mm vs. 40.64 mm, p=0.802). Compression rate fell with all devices (pressure sensor device 114.68-98.84 min(-1), p=0.001, accelerometer 112.04-102.92 min(-1), p=0.072 and metronome 108.24 min(-1) vs. 99.36 min(-1), p=0.009). The pressure sensor feedback device reduced the proportion of compressions with inadequate depth (0.52 vs. 0.24, p=0.013) whilst the accelerometer device and metronome did not have a statistically significant effect. Incomplete release of compressions was common, but unaffected by the CPR feedback devices. Users preferred the accelerometer and metronome devices over the pressure sensor device. A post hoc study showed that de-activating the voice prompt on the accelerometer device prevented the deterioration in compression quality seen in the main study. CONCLUSION: CPR feedback devices vary in their ability to improve performance. In this study the pressure sensor device improved compression depth, whilst the accelerometer device reduced it and metronome had no effect.",2014-04,13/11/2018 10:47,14/04/2020 08:38,,553-559,,4,85,,Resuscitation,,,,,,,,eng,Copyright (c) 2014 Elsevier Ireland Ltd. All rights reserved.,,,,,,PMID: 24463223,,,,"Humans; *Quality of Health Care; Quality of Health Care; Adult; Female; Male; Middle Aged; Young Adult; Heart Arrest/*therapy; Resuscitation; Single-Blind Method; Manikins; Body Size; Education; Pressure; Human; Models; Middle Age; Anatomic; Heart Arrest – Therapy; Accelerometry – Equipment and Supplies; Cardiopulmonary – Equipment and Supplies; Cues; Heart Massage – Equipment and Supplies; Psychotherapy; Single-Blind Studies; 00; *Cues; *Feedback, Sensory; Accelerometry/instrumentation; Cardiopulmonary Resuscitation/*instrumentation; Chest compression; Feedback devices; Heart Massage/*instrumentation; Training; 110; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5HK6QRPX,journalArticle,2016,"Goh, Yang Miang; Askar Ali, Mohamed Jawad",A hybrid simulation approach for integrating safety behavior into construction planning: An earthmoving case study.,Accident; analysis and prevention,,1879-2057 0001-4575,10.1016/j.aap.2015.09.015,,"One of the key challenges in improving construction safety and health is the management of safety behavior. From a system point of view, workers work unsafely due to system level issues such as poor safety culture, excessive production pressure, inadequate allocation of resources and time and lack of training. These systemic issues should be eradicated or minimized during planning. However, there is a lack of detailed planning tools to help managers assess the impact of their upstream decisions on worker safety behavior. Even though simulation had been used in construction planning, the review conducted in this study showed that construction safety management research had not been exploiting the potential of simulation techniques. Thus, a hybrid simulation framework is proposed to facilitate integration of safety management considerations into construction activity simulation. The hybrid framework consists of discrete event simulation (DES) as the core, but heterogeneous, interactive and intelligent (able to make decisions) agents replace traditional entities and resources. In addition, some of the cognitive processes and physiological aspects of agents are captured using system dynamics (SD) approach. The combination of DES, agent-based simulation (ABS) and SD allows a more ""natural"" representation of the complex dynamics in construction activities. The proposed hybrid framework was demonstrated using a hypothetical case study. In addition, due to the lack of application of factorial experiment approach in safety management simulation, the case study demonstrated sensitivity analysis and factorial experiment to guide future research.",2016-08,13/11/2018 10:47,14/04/2020 08:34,,310-318,,,93,,Accid Anal Prev,,,,,,,,eng,Copyright (c) 2015 Elsevier Ltd. All rights reserved.,,,,,,PMID: 26456000,,,,"Humans; *Computer Simulation; *Risk-Taking; Data Collection; Inservice Training; Organizational Culture; Systems Theory; 00; Accidents, Occupational/*prevention & control; Activity planning; Aptitude; Construction Industry/*organization & administration; Construction safety; Hybrid simulation; Occupational Health/*standards; Safety behavior; Safety Management/*methods/*organization & administration; Simulation methodology; Singapore; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2V2ECNM5,journalArticle,2017,"Billeci, Lucia; Varanini, Maurizio",A Combined Independent Source Separation and Quality Index Optimization Method for Fetal ECG Extraction from Abdominal Maternal Leads.,"Sensors (Basel, Switzerland)",,1424-8220 1424-8220,10.3390/s17051135,,"The non-invasive fetal electrocardiogram (fECG) technique has recently received considerable interest in monitoring fetal health. The aim of our paper is to propose a novel fECG algorithm based on the combination of the criteria of independent source separation and of a quality index optimization (ICAQIO-based). The algorithm was compared with two methods applying the two different criteria independently-the ICA-based and the QIO-based methods-which were previously developed by our group. All three methods were tested on the recently implemented Fetal ECG Synthetic Database (FECGSYNDB). Moreover, the performance of the algorithm was tested on real data from the PhysioNet fetal ECG Challenge 2013 Database. The proposed combined method outperformed the other two algorithms on the FECGSYNDB (ICAQIO-based: 98.78%, QIO-based: 97.77%, ICA-based: 97.61%). Significant differences were obtained in particular in the conditions when uterine contractions and maternal and fetal ectopic beats occurred. On the real data, all three methods obtained very high performances, with the QIO-based method proving slightly better than the other two (ICAQIO-based: 99.38%,",16/05/2017,13/11/2018 10:47,14/04/2020 08:34,,,,5,17,,Sensors (Basel),,,,,,,,eng,,,,,,,PMID: 28509860 PMCID: PMC5470811,,,,"Humans; Female; Algorithms; Pregnancy; *Electrocardiography; Abdomen; abdominal ECG; fetal ECG extraction; Fetus; independent component analysis (ICA); optimization; quality index; Signal Processing, Computer-Assisted; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5FUKY292,journalArticle,2014,"Duane, B.; Taylor, T.; Stahl-Timmins, W.; Hyland, J.; Mackie, P.; Pollard, A.","Carbon mitigation, patient choice and cost reduction--triple bottom line optimisation for health care planning.",Public health,,1476-5616 0033-3506,10.1016/j.puhe.2014.08.008,,"OBJECTIVES: Health services must provide safe, affordable clinical care whilst meeting efficiency, environmental and social targets. These targets include achieving reduced greenhouse gas emissions. A care pathway approach based on a decision-support tool can simultaneously reconfigure health services, improve productivity and reduce carbon emissions. STUDY DESIGN: Probabilistic modelling using secondary data analysis. METHODS: Estimates of carbon emitted by a health service drew on a previous carbon accounting study which integrated bottom-up assessment of carbon emissions with top-down analysis of indirect emissions by Duane et al. (2012).(1) Using human resource information, estimates were applied in a decision-support model to measure the carbon footprint and service provision of theoretical scenarios. Using this model, sites with less than 60% utilisation were theoretically reconfigured to reduce carbon emissions and improve service provision. RESULTS: Clinic utilisation rates improved from 50% to 78%. Human resource savings were identified which could be re-directed towards improving patient care. Patient travel for health care was halved resulting in significant savings in carbon emissions. CONCLUSIONS: The proposed model is an effective health care service analysis tool, ensuring optimal utilisation of health care sites and human resources with the lowest carbon footprint.",2014-10,13/11/2018 10:47,14/04/2020 08:34,,920-924,,10,128,,Public Health,,,,,,,,eng,Copyright (c) 2014 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.,,,,,,PMID: 25304168,,,,"Humans; *Cost Savings; Models, Theoretical; United Kingdom; Delivery of Health Care/*economics; 1; *Carbon Footprint; *Patient Preference; Carbon; Greenhouse gases; Health Planning/*organization & administration; Service management; Service redesign; Sustainability; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7SADMJLY,journalArticle,2015,"Ma, Junsheng; Chan, Wenyaw; Tsai, Chu-Lin; Xiong, Momiao; Tilley, Barbara C.",Analysis of transtheoretical model of health behavioral changes in a nutrition intervention study--a continuous time Markov chain model with Bayesian approach.,Statistics in medicine,,1097-0258 0277-6715,10.1002/sim.6571,,"Continuous time Markov chain (CTMC) models are often used to study the progression of chronic diseases in medical research but rarely applied to studies of the process of behavioral change. In studies of interventions to modify behaviors, a widely used psychosocial model is based on the transtheoretical model that often has more than three states (representing stages of change) and conceptually permits all possible instantaneous transitions. Very little attention is given to the study of the relationships between a CTMC model and associated covariates under the framework of transtheoretical model. We developed a Bayesian approach to evaluate the covariate effects on a CTMC model through a log-linear regression link. A simulation study of this approach showed that model parameters were accurately and precisely estimated. We analyzed an existing data set on stages of change in dietary intake from the Next Step Trial using the proposed method and the generalized multinomial logit model. We found that the generalized multinomial logit model was not suitable for these data because it ignores the unbalanced data structure and temporal correlation between successive measurements. Our analysis not only confirms that the nutrition intervention was effective but also provides information on how the intervention affected the transitions among the stages of change. We found that, compared with the control group, subjects in the intervention group, on average, spent substantively less time in the precontemplation stage and were more/less likely to move from an unhealthy/healthy state to a healthy/unhealthy state.",30/11/2015,13/11/2018 10:47,14/04/2020 08:34,,3577-3589,,27,34,,Stat Med,,,,,,,,eng,"Copyright (c) 2015 John Wiley & Sons, Ltd.",,,,,,PMID: 26123093 PMCID: PMC4626363,,,,"Humans; Surveys and Questionnaires; Female; Male; Middle Aged; Aged; *Markov Chains; Linear Models; *Health Behavior; *Bayes Theorem; Empirical Research; *Feeding Behavior; *Models, Psychological; Bayesian data analysis; covariates; Markov chain models; Metropolis-Hastings algorithm; transtheoretical models; 1; 410",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, U9GXUAVE,journalArticle,2018,"Ng, Lai Peng; Koh, Eileen Yi Ling",Intrauterine contraceptive device insertion simulation training in primary care,PROCEEDINGS OF SINGAPORE HEALTHCARE,,2010-1058,10.1177/2010105818757558,,Background and objectives: Insertion of a intrauterine contraceptive device (IUCD) is one of the services provided at our public primary care polyclinics. We evaluate the effectiveness of a simulation workshop using low-fidelity mannequins to train primary care doctors. Methods: Questionnaire feedback was collected before and after the workshop. Participants rated their confidence level in performing the insertion of IUCDs using a 10-point scale. Results: A total of 37 out of 44 (84%) participants completed the survey. The median score for confidence level in performing the procedure increased from 2 out of 10 (interquartile range (IQR) 1 to 5) before the workshop to 8 out of 10 (IQR 7 to 9) after the workshop (p < 0.01). The increase in confidence level was most pronounced among the participants with no previous experience with the procedure and those who had inserted only one or two IUCDs before the workshop. Participants rated a median score of 9 out of 10 (IQR 8 to 10) in their interest level to perform the procedure after the workshop. The overall experience of the workshop recorded a median score of 5 out of 5 using a five-point Likert scale. Conclusions: Bedside procedural training has been challenging. The teaching of the procedure via a structured workshop format including a simulation of the procedure using a low-fidelity mannequin increases the confidence level of participants to perform the procedure. A similar format can be employed for training of other primary care procedural skills.,2018-12,21/11/2018 10:57,14/04/2020 08:35,,229-233,,4,27,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CVGER3CF,journalArticle,2018,"Kata, Anna; Sudore, Rebecca; Finlayson, Emily; Broering, Jeanette M.; Ngo, Sarah; Tang, Victoria L.",Increasing Advance Care Planning Using a Surgical Optimization Program for Older Adults,JOURNAL OF THE AMERICAN GERIATRICS SOCIETY,,0002-8614,10.1111/jgs.15554,,"ObjectivesTo describe an innovative model of care, the Surgery Wellness Program (SWP), that uses a multidisciplinary team to develop and implement preoperative care plans for older adults, and its effect on engagement in advance care planning (ACP). DesignRetrospective analysis of clinical demonstration project. SettingPreoperative optimization program for older adults undergoing surgery at a 796-bed academic tertiary hospital. ParticipantsOlder adults (N=131) who participated in the SWP from February 2015 to August 2017. InterventionAll SWP participants met with a geriatrician who engaged them in a semistructured ACP discussion. Trained medical and nurse practitioner students were used as health coaches who contacted participants regularly to address and document ACP. MeasurementsSelf-report of ACP engagement before and after participation in the SWP was determined using SWP geriatrician and health coach progress notes. Medical records were examined for scanned documentation. Feasibility data on number of health coach calls were collected. ResultsAfter completion of the program, the proportion of participants with a designated surrogate increased from 67% to 78% (p<.001), completed advance directive (AD) from 51% to 72% (p<.001), and an AD scanned into the medical record from 14% to 60% (p<.001). Participants who underwent surgery received a median of 4 health coaching calls over a median of 27 days between their clinic visit and surgery. Case examples are presented to highlight how the SWP attends to the many components of the ACP process. ConclusionPreoperative optimization programs provide a unique opportunity to engage older adults in ACP.",2018-10,21/11/2018 10:57,14/04/2020 08:34,,2017-2021,,10,66,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, V8E2YT37,journalArticle,2018,"Cappanera, Paola; Scutella, Maria Grazia; Nervi, Federico; Galli, Laura",Demand uncertainty in robust Home Care optimization,OMEGA-INTERNATIONAL JOURNAL OF MANAGEMENT SCIENCE,,0305-0483,10.1016/j.omega.2017.08.012,,"We study the Home Care Problem under uncertainty. Home Care refers to medical, paramedical and social services that may be delivered to patient homes. The term includes several aspects involved in the planning of home care services, such as caregiver-to-patient assignment, scheduling of patient requests, and caregiver routing. In Home Care, cancellation of requests and additional demand for known or new patients are very frequent. Thus, managing demand uncertainty is of paramount importance in limiting service disruptions that might occur when such events realize. We address uncertainty of patient demand over a multiple-day time horizon, when assignment, scheduling and routing decisions are taken jointly, both from a methodological and a computational perspective. In fact, we propose a non-standard cardinality-constrained robust approach, analyse its properties, and report the results of a wide experimentation on real-life instances. The obtained results show that, for instances of moderate size, the approach is able to efficiently determine robust solutions of good quality in terms of balancing among caregivers and number of uncertain requests that can be managed. Also, the robustness of the solutions with respect to possible realizations of uncertain requests, evaluated on a small subset of instances, appears to be significant. Furthermore, preliminary experiments on a decomposition method, obtained from the robust one by fixing the scheduling decisions, show a drastic gain in computational efficiency, with the determination of robust solutions of still good quality. Therefore, the approach appears to be very promising to cope with robustness even on Home Care instances of larger size. (C) 2017 Elsevier Ltd. All rights reserved.",2018-10,21/11/2018 10:57,14/04/2020 08:34,,95-110,,,80,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CHGPVN6Z,journalArticle,2018,"Olmos, Pablo; Borzone, Gisella; Poblete, Andres",47-Fold rise of diabetes in childbearing age Chilean women: Markov model and cost-effectiveness of prevention of birth defects,JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH,,1341-8076,10.1111/jog.13712,,"AimPrevalence of type 2 diabetes mellitus (T2DM) during childbearing age in Chile had a 47-fold rise in 7 years, reaching 120 844 women, half of which are unaware of their condition. We aimed to project pregnancies and births among Chilean women of childbearing age (WCBA) with T2DM and report the incidence of birth defects and the associated years of life lost and lifetime costs. MethodsMarkov model of cohort of WCBA with T2DM (WCBA-DM) with a 20-year time horizon (2018-2037), using data from previous studies. Two scenarios were assessed: scenario A: no universal detection of T2DM and scenario B: universal screening of T2DM using glycosylated hemoglobin levels. Both lifetime costs and disability-adjusted life years (DALY) were calculated with a 5% discount rate (US$ of 2017). ResultsIn scenario A, 12 163 infants with birth defects could be born among the analyzed cohort, resulting in 243 260 years of life lost, 296 652 DALY and in lifetime costs of US$ 1 957 657 966. In scenario B, the first three figures could be reduced by 70.4% to 3599 infants with birth defects, 71 980 years of life lost and 87 794 DALY. Due to the addition of diabetes screening and new patient costs to scenario B, there would be a lesser reduction (67.3%) in total lifetime costs, to US$ 640 669 296. ConclusionScreening of diabetes in WCBA would yield a 20-year reduction of 70.4% in the number of infants with birth defects, years of life lost and DALY. Total lifetime costs could be reduced by 67.3%.",2018-09,21/11/2018 10:57,14/04/2020 08:35,,1719-1730,,9,44,,,,,,,,,,,,,,,,,,,,,1; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BR9W9KMT,journalArticle,2018,"Jessani, Nasreen S.; Babcock, Carly; Siddiqi, Sameer; Davey-Rothwell, Melissa; Ho, Shirley; Holtgrave, David R.",Relationships between public health faculty and decision makers at four governmental levels: a social network analysis,EVIDENCE & POLICY,,1744-2648,10.1332/174426418X15230282334424,,"Background Relationships between academic faculty and decision makers have been documented as an important factor in the evidence-to-policy process. However, knowledge about the breadth, depth and dynamic quality of these relationships often remains unknown therefore rendering the potential for influence untapped, uncoordinated, redundant or inefficient. Methods We mapped the relationships between faculty at the Johns Hopkins Bloomberg School of Public Health and decision makers at the city, state, federal and global levels. In 2016, 211 of 627 eligible full-time faculty participated in a sociometric survey. Common metrics for social network analysis were modified to provide reliable indicators of network characteristics. UCINet was used for network visualisation. `Highly connected' individuals included: faculty with >= 5 contacts at any one government level; those appearing in the top 10% in total across all four levels; decision makers appearing in the top 2% of frequently mentioned people. Results Results revealed faculty relationships spanning >100 government departments, similar to 700 decision makers, and 45 country governments. The majority of respondents (72%) mentioned at least one decision maker; 49 faculty and 24 decision makers appeared as `highly connected'. While the School of Public Health (SPH) demonstrates a diversity of relationships within and across government agencies, there were also identifiable gaps. Conclusion This study provides further support for using Network Analysis to explore size, reach, diversity and density of relationships between academic faculty and decision makers, with network maps serving as a proxy for potential influence. Academic institutions and government agencies should nurture a variety of relationships in order to enhance engaged scholarship and further informed decision making.",2018-08,21/11/2018 10:57,14/04/2020 08:34,,499-522,,"3, SI",14,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TELX8TI5,journalArticle,2018,"Frerichs, Leah; Young, Tiffany L.; Dave, Gaurav; Stith, Doris; Corbie-Smith, Giselle; Lich, Kristen Hassmiller",Mind maps and network analysis to evaluate conceptualization of complex issues: A case example evaluating systems science workshops for childhood obesity prevention,EVALUATION AND PROGRAM PLANNING,,0149-7189,10.1016/j.evalprogplan.2018.03.003,,"Across disciplines, it is common practice to bring together groups to solve complex problems. Facilitators are often asked to help groups organize information about and better understand the problem in order to develop and prioritize solutions. However, despite existence of several methods to elicit and characterize how individuals and groups think about and conceptualize an issue, many are difficult to implement in practice-based settings where resources such as technology and participant time are limited and research questions shift over time. This paper describes an easy-to-implement diagramming technique for eliciting conceptualization and a flexible network analysis method for characterizing changes in both individual and group conceptualization. We use a case example to illustrate how we used the methods to evaluate African American adolescent's conceptual understanding of obesity before and after participating in a series of four systems thinking workshops. The methods produced results that were sensitive to changes in conceptualization that were likely driven by the specific activities employed during the workshop sessions. The methods appear strong for capturing salient levels of conceptualization at both individual and collective levels. The paper concludes with a critical examination of strengths and weaknesses of the methods and implications for future practice and research.",2018-06,21/11/2018 10:57,14/04/2020 08:34,,135-147,,,68,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WYGQ4FWB,journalArticle,2018,"Frerichs, Leah; Lich, Kristen Hassmiller; Young, Tiffany L.; Dave, Gaurav; Stith, Doris; Corbie-Smith, Giselle",Development of a Systems Science Curriculum to Engage Rural African American Teens in Understanding and Addressing Childhood Obesity Prevention,HEALTH EDUCATION & BEHAVIOR,,1090-1981,10.1177/1090198117726570,,"Engaging youth from racial and ethnic minority communities as leaders for change is a potential strategy to mobilize support for addressing childhood obesity, but there are limited curricula designed to help youth understand the complex influences on obesity. Our aim was to develop and pilot test a systems science curriculum to elicit rural African American youth perspectives on childhood obesity and enhance their understanding of and support for obesity prevention solutions. The curriculum was designed so it could be integrated with existing positive youth development curricula that help youth advocate for and implement identified solutions. We conducted four workshop sessions with youth that engaged them in systems learning activities such as guided systems diagramming activities. The participants (n = 21) completed validated surveys presession and postsession that assessed their causal attributions of obesity and support for obesity prevention policies. The youths' perception that environmental factors cause obesity increased (p < .05), and perceptions that individual behavior and biology cause obesity did not change. Their support for policies that addressed food access and food pricing significantly increased (p < .05). The youths' system diagrams elucidated links between multilevel factors such as personal attitudes, social influence, and the built environment, which provides important information for designing synergistic solutions. The changes we observed in youths' perceptions of obesity and support for policy changes have important implications for youths' interest and willingness to advocate for social and environmental changes in their community. The strategies have a promising role in supporting community mobilization to address childhood obesity.",2018-06,21/11/2018 10:57,14/04/2020 08:34,,423-434,,3,45,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, A6BI8DMN,journalArticle,2018,"Bonner, Carissa; McKinn, Shannon; Lau, Annie; Jansen, Jesse; Doust, Jenny; Trevena, Lyndal; McCaffery, Kirsten","Heuristics and biases in cardiovascular disease prevention: How can we improve communication about risk, benefits and harms?",PATIENT EDUCATION AND COUNSELING,,0738-3991,10.1016/j.pec.2017.12.003,,"Objective: Cardiovascular disease (CVD) prevention guidelines recommend medication based on the probability of a heart attack/stroke in the next 5-10 years. However, heuristics and biases make risk communication challenging for doctors. This study explored how patients interpret personalised CVD risk results presented in varying formats and timeframes. Methods: GPs recruited 25 patients with CVD risk factors and varying medication history. Participants were asked to `think aloud' while using two CVD risk calculators that present probabilistic risk in different ways, within a semi-structured interview. Transcribed audio-recordings were coded using Framework Analysis. Results: Key themes were: 1) numbers lack meaning without a reference point; 2) risk results need to be both credible and novel; 3) selective attention to intervention effects. Risk categories (low/moderate/high) provided meaningful context, but short-term risk results were not credible if they didn't match expectations. Colour-coded icon arrays showing the effect of age and interventions were seen as novel and motivating. Those on medication focused on benefits, while others focused on harms. Conclusion: CVD risk formats need to be tailored to patient expectations and experiences in order to counteract heuristics and biases. Practice implications: Doctors need access to multiple CVD risk formats to communicate effectively about CVD prevention. (C) 2017 Elsevier B.V. All rights reserved.",2018-05,21/11/2018 10:57,14/04/2020 08:34,,843-853,,5,101,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FH2DX739,journalArticle,2018,"McGlashan, Jaimie; Nichols, Melanie; Korn, Ariella; Millar, Lynne; Marks, Jennifer; Sanigorski, Andrew; Pachucki, Mark; Swinburn, Boyd; Allender, Steven; Economos, Christina",Social network analysis of stakeholder networks from two community-based obesity prevention interventions,PLOS ONE,,1932-6203,10.1371/journal.pone.0196211,,"Introduction Studies of community-based obesity prevention interventions have hypothesized that stake-holder networks are a critical element of effective implementation. This paper presents a quantitative analysis of the interpersonal network structures within a sub-sample of stake-holders from two past successful childhood obesity prevention interventions. Methods Participants were recruited from the stakeholder groups (steering committees) of two completed community-based intervention studies, Romp & Chomp (R&C), Australia (2004-2008) and Shape Up Somerville (SUS), USA (2003-2005). Both studies demonstrated significant reductions of overweight and obesity among children. Members of the steering committees were asked to complete a retrospective social network questionnaire using a roster of other committee members and free recall. Each participant was asked to recall the people with whom they discussed issues related to childhood obesity throughout the intervention period, along with providing the closeness and level of influence of each relationship. Results Networks were reported by 13 participants from the SUS steering committee and 8 participants from the R&C steering committee. On average, participants nominated 16 contacts with whom they discussed issues related to childhood obesity through the intervention, with approximately half of the relationships described as `close' and 30% as `influential'. The `discussion' and `close' networks had high clustering and reciprocity, with ties directed to other steering committee members, and to individuals external to the committee. In contrast, influential ties were more prominently directed internal to the steering committee, with higher network centralization, lower reciprocity and lower clustering. Discussion and conclusion Social network analysis provides a method to evaluate the ties within steering committees of community-based obesity prevention interventions. In this study, the network characteristics between a sub-set of stakeholders appeared to be supportive of diffused communication. Future work should prospectively examine stakeholder network structures in a heterogeneous sample of community-based interventions to identify elements most strongly associated with intervention effectiveness.",27/04/2018,21/11/2018 10:57,14/04/2020 08:34,,,,4,13,,,,,,,,,,,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3HNVEGMR,journalArticle,2018,"Mitchell, Dominic; Guertin, Jason R.; Dubois, Anick; Dube, Marie-Pierre; Tardif, Jean-Claude; Iliza, Ange Christelle; Fanton-Aita, Fiorella; Matteau, Alexis; LeLorier, Jacques",A Discrete Event Simulation Model to Assess the Economic Value of a Hypothetical Pharmacogenomics Test for Statin-Induced Myopathy in Patients Initiating a Statin in Secondary Cardiovascular Prevention,MOLECULAR DIAGNOSIS & THERAPY,,1177-1062,10.1007/s40291-018-0323-2,,"Background Statin (HMG-CoA reductase inhibitor) therapy is the mainstay dyslipidemia treatment and reduces the risk of a cardiovascular (CV) event (CVE) by up to 35%. However, adherence to statin therapy is poor. One reason patients discontinue statin therapy is musculoskeletal pain and the associated risk of rhabdomyolysis. Research is ongoing to develop a pharmacogenomics (PGx) test for statin-induced myopathy as an alternative to the current diagnosis method, which relies on creatine kinase levels. The potential economic value of a PGx test for statin-induced myopathy is unknown. Methods We developed a lifetime discrete event simulation (DES) model for patients 65 years of age initiating a statin after a first CVE consisting of either an acute myocardial infarction (AMI) or a stroke. The model evaluates the potential economic value of a hypothetical PGx test for diagnosing statin-induced myopathy. We have assessed the model over the spectrum of test sensitivity and specificity parameters. Results Our model showed that a strategy with a perfect PGx test had an incremental cost-utility ratio of 4273 Canadian dollars ($Can) per quality-adjusted life year (QALY). The probabilistic sensitivity analysis shows that when the payer willingness-to-pay per QALY reaches $Can12,000, the PGx strategy is favored in 90% of the model simulations. Conclusion We found that a strategy favoring patients staying on statin therapy is cost effective even if patients maintained on statin are at risk of rhabdomyolysis. Our results are explained by the fact that statins are highly effective in reducing the CV risk in patients at high CV risk, and this benefit largely outweighs the risk of rhabdomyolysis.",2018-04,21/11/2018 10:57,14/04/2020 08:34,,241-254,,2,22,,,,,,,,,,,,,,,,,,,,,1; 100; 120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, T733J8ZR,journalArticle,2018,"McKinnon, Tamara; Brunetto, Laura; Teaford, Dominique; Meszaros, Michelle; O'Leary-Kelley, Colleen",`'The First Knock”: A Public Health Nursing Simulation,CLINICAL SIMULATION IN NURSING,,1876-1399,10.1016/j.ecns.2017.11.011,,"A simulated initial home visit, First Knock, was conceived to address anxiety and reticence seen in student and novice nurses before their first home visit in the public health setting. The First Knock aims to provide an opportunity for learners to reflect on issues, challenges, and ethical dilemmas likely experienced during home visits. This article provides background literature on the use of simulation in public health and describes the First Knock simulation. (C) 2017 International Nursing Association for Clinical Simulation and Learning. Published by Elsevier Inc. All rights reserved.",2018-04,21/11/2018 10:57,14/04/2020 08:34,,14-18,,,17,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2RSZAFIQ,journalArticle,2018,"Shafiee, M. Ehsan; Berglund, Emily Zechman; Lindell, Michael K.",An Agent-based Modeling Framework for Assessing the Public Health Protection of Water Advisories,WATER RESOURCES MANAGEMENT,,0920-4741,10.1007/s11269-018-1916-6,,"In the event that pathogens or toxins are introduced to a water distribution system, a utility manager may identify a threat through water quality data or alerts from public health officials. The utility manager may issue water advisories to warn consumers to reduce water use activities. As consumers react and change water demands, dynamic feedbacks among the community, utility managers, and the engineering infrastructure can create unexpected public health consequences and network hydraulics. A Complex Adaptive System (CAS)-based methodology is developed to couple an engineering model of a water distribution system with agent-based models (ABM) of consumers, public health officials, and utility managers to simulate feedback among management decisions, system hydraulics, and public behavior. A utility manager and a public health official are represented as agents, who respond to the event using a set of rules and equations that are based on a statistical analysis of a set of recorded water events. Consumers are represented as agents who update their water activities based on exposure to the contaminant and warnings from a utility agent and family members. A model of consumer compliance is developed using results from two surveys that report data to characterize consumer perceptions toward information sources during a water contamination event. The ABM framework is applied for an illustrative mid-sized virtual city to quantify the significance of interactions and advisories on public health consequences.",2018-04,21/11/2018 10:57,14/04/2020 08:35,,2033-2059,,6,32,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, SFGRR7QY,journalArticle,2018,"Liu, Shiyong; Xue, Hong; Li, Yan; Xu, Judy; Wang, Youfa",Investigating the Diffusion of Agent-based Modelling and System Dynamics Modelling in Population Health and Healthcare Research,SYSTEMS RESEARCH AND BEHAVIORAL SCIENCE,,1092-7026,10.1002/sres.2460,,"System dynamics modelling (SDM) applications in health research began to appear in 1972 while agent-based modelling (ABM) applications first appeared in 1995, but their applications have increased dramatically over the last decade. This study examines the diffusion patterns of these two approaches and the main driving factors. We conducted a systematic analysis of 653 journal articles published from 1972 to 2014 that employed two approaches in health research and found that over the last few years, there has been a rapid increase of studies in using ABM compared with SDM, partly due to the launching of new journals and the application of ABM to a broad range of topics. The concentration of SDM studies in just a few journals may be adversely affecting its diffusion. The last decade saw acceleration in using ABM to investigate infectious diseases and cancer while SDM applications have predominantly focused on non-communicable diseases such as obesity. Copyright (c) 2017 John Wiley & Sons, Ltd.",2018-04,21/11/2018 10:57,14/04/2020 08:34,,203-215,,2,35,,,,,,,,,,,,,,,,,,,,,System dynamics; 1; ******To read; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KFMT7WWV,journalArticle,2018,"Apostolopoulos, Yorghos; Lemke, Michael K.; Barry, Adam E.; Lich, Kristen Hassmiller",y Moving alcohol prevention research forwardPart I: introducing a complex systems paradigm,ADDICTION,,0965-2140,10.1111/add.13955,,"Background and aimsThe drinking environment is a complex system consisting of a number of heterogeneous, evolving and interacting components, which exhibit circular causality and emergent properties. These characteristics reduce the efficacy of commonly used research approaches, which typically do not account for the underlying dynamic complexity of alcohol consumption and the interdependent nature of diverse factors influencing misuse over time. We use alcohol misuse among college students in the United States as an example for framing our argument for a complex systems paradigm. MethodsA complex systems paradigm, grounded in socio-ecological and complex systems theories and computational modeling and simulation, is introduced. Theoretical, conceptual, methodological and analytical underpinnings of this paradigm are described in the context of college drinking prevention research. ResultsThe proposed complex systems paradigm can transcend limitations of traditional approaches, thereby fostering new directions in alcohol prevention research. By conceptualizing student alcohol misuse as a complex adaptive system, computational modeling and simulation methodologies and analytical techniques can be used. Moreover, use of participatory model-building approaches to generate simulation models can further increase stakeholder buy-in, understanding and policymaking. ConclusionsA complex systems paradigm for research into alcohol misuse can provide a holistic understanding of the underlying drinking environment and its long-term trajectory, which can elucidate high-leverage preventive interventions.",2018-02,21/11/2018 10:57,14/04/2020 08:34,,353-362,,2,113,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, J3FVARMF,journalArticle,2018,"Apostolopoulos, Yorghos; Lemke, Michael K.; Barry, Adam E.; Lich, Kristen Hassmiller",Moving alcohol prevention research forwardPart II: new directions grounded in community-based system dynamics modeling,ADDICTION,,0965-2140,10.1111/add.13953,,"Background and aimsGiven the complexity of factors contributing to alcohol misuse, appropriate epistemologies and methodologies are needed to understand and intervene meaningfully. We aimed to (1) provide an overview of computational modeling methodologies, with an emphasis on system dynamics modeling; (2) explain how community-based system dynamics modeling can forge new directions in alcohol prevention research; and (3) present a primer on how to build alcohol misuse simulation models using system dynamics modeling, with an emphasis on stakeholder involvement, data sources and model validation. Throughout, we use alcohol misuse among college students in the United States as a heuristic example for demonstrating these methodologies. MethodsSystem dynamics modeling employs a top-down aggregate approach to understanding dynamically complex problems. Its three foundational propertiesstocks, flows and feedbackscapture non-linearity, time-delayed effects and other system characteristics. As a methodological choice, system dynamics modeling is amenable to participatory approaches; in particular, community-based system dynamics modeling has been used to build impactful models for addressing dynamically complex problems. ResultsThe process of community-based system dynamics modeling consists of numerous stages: (1) creating model boundary charts, behavior-over-time-graphs and preliminary system dynamics models using group model-building techniques; (2) model formulation; (3) model calibration; (4) model testing and validation; and (5) model simulation using learning-laboratory techniques. ConclusionsCommunity-based system dynamics modeling can provide powerful tools for policy and intervention decisions that can result ultimately in sustainable changes in research and action in alcohol misuse prevention.",2018-02,21/11/2018 10:57,14/04/2020 08:34,,363-371,,2,113,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EEHWAISG,conferencePaper,2018,"Faria, Joana; Cardoso-Grilo, Teresa; Gomes, Cristina",Planning Health Workforce Training in the Detection and Prevention of Excessive Alcohol Consumption: An Optimization-Based Approach,OPERATIONAL RESEARCH,978-3-319-71583-4 978-3-319-71582-7,,10.1007/978-3-319-71583-4_6,,"The adequate training of health workforce in the field of excessive alcohol consumption is essential to provide health professionals with the necessary tools for an adequate provision of care, thus leading to a decrease in alcohol consumption. Proper planning of such training is thus essential, but literature in this area is still scarce. This paper proposes an optimization model based on mathematical programming for supporting the planning of healthworkforce training in the field of excessive alcohol consumption in National Health Service-based countries - the WFTMalcohol. The model aims at informing on (i) how many health professionals (physicians and nurses) should be trained per year and health unit, and (ii) which training packages should be available per year. The model allows exploring the impact of considering different objectives relevant in this sector, including the minimization of costs and the maximization of multiple performance indicators. Acknowledging that several sources of uncertainty may affect planning decisions, a sensitivity analysis on key parameters of the model is performed. To illustrate the applicability of the model, a case study based on the Oeste Sul ACES in Lisbon is analyzed. Results confirm that there is a shortage of trained professionals in this field in Portugal.",2018,21/11/2018 10:57,14/04/2020 08:34,,69-86,,,223,,,,Springer Proceedings in Mathematics & Statistics,,,,Portuguese Assoc Operat Res,,,,,,,,,,"

18th Congress of the Portuguese-Association-of-Operational-Research (APDIO), Valenca, PORTUGAL, JUN 28-30, 2017

",,,00; 110,,"Vaz, AIF and Almeida, JP and Oliveira, JF and Pinto, AA",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7GK9CRYW,journalArticle,2018,"Tohidifard, M.; Tavakkoli-Moghaddam, R.; Navazi, F.; Partovi, M.",A Multi-Depot Home Care Routing Problem with Time Windows and Fuzzy Demands Solving by Particle Swarm Optimization and Genetic Algorithm,IFAC PAPERSONLINE,,2405-8963,10.1016/j.ifacol.2018.08.318,,"Providing sanitarian and medical treatments for patients in their location has lots of benefits. Having ordered and on-time medical services cause faster recovery for patients, besides reducing their expenditure. This study presents a new mathematical model for a multi-depot vehicle routing problem (VRP) with time windows for home health care firms. The multi-depot VRP tries to visit some patients and give necessary services to them by several vehicles settled at multiple depots. The endeavor of this problem is raising the satisfaction of patients while minimizing the distance and time of the traveling tour, the number of vehicles, and the transportation cost in a patient's hard time windows. The problem is solved by genetic algorithm (GA) and particle swarm optimization (PSO). The related results are compared with the GAMS outcomes for small-sized problems. (C) 2018, IFAC (International Federation of Automatic Control) Hosting by Elsevier Ltd. All rights reserved.",2018,21/11/2018 10:57,14/04/2020 08:35,,358-363,,11,51,,,,,,,,,,,,,,,,,,"

16th IFAC Symposium on Information Control Problems in Manufacturing (INCOM), Bergamo, ITALY, JUN 11-13, 2018

",,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, E8GMTGVD,journalArticle,2018,"Akhbar, Mohd Faizal Ali; Yusoff, Ahmad Razlan",Optimization of drilling parameters for thermal bone necrosis prevention,TECHNOLOGY AND HEALTH CARE,,0928-7329,10.3233/THC-181221,,"BACKGROUND: Bone drilling is a mandatory process in orthopedic surgery to fix the fractured bones. Excessive heat is generated due to the shear deformation of bone and friction energy during the drilling process. OBJECTIVE: This paper is carried out to optimize the bone drilling parameters to prevent thermal bone necrosis. The main contribution of this work is instead of only consider the influence of rotational speed and feed rate, the effect of tool diameter and drilling hole depth are also incorporated for optimization study. METHODS: Response surface methodology (RSM) was used to develop a temperature prediction model. Drilling experiments were performed using finite element software DEFORM-3D. Analysis of variance (ANOVA) was conducted to investigate the drilling parameters' effect. Desirability function in RSM was used to determine the optimum combination of drilling parameters. RESULTS: Results indicated that one applicable combination of drilling parameters could increase the bone temperature by less than 0.03%. To avoid thermal bone necrosis, eight reasonable combinations of drilling parameters were proposed. 3.3 degrees C residuals between in-vitro experiments and predicted values were demonstrated. CONCLUSIONS: It is envisaged that finite element simulation with RSM can simplify tedious experimental works and useful in the clinical application to avoid bone necrosis.",2018,21/11/2018 10:57,14/04/2020 08:34,,621-635,,4,26,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IQFMN9LL,journalArticle,2018,"de Queiroz, J. A. M.; Aragon, D. C.; de Mello, L. M.; Previdelli, I. T. S.; Martinez, E. Z.",Using a Bayesian change-point statistical model with autoregressive terms to study the monthly number of dispensed asthma medications by public health services,SORT-STATISTICS AND OPERATIONS RESEARCH TRANSACTIONS,,1696-2281,10.2436/20.8080.02.66,,"In this paper, it is proposed a Bayesian analysis of a time series in the presence of a random change-point and autoregressive terms. The development of this model was motivated by a data set related to the monthly number of asthma medications dispensed by the public health services of Ribeirao Preto, Southeast Brazil, from 1999 to 2011. A pronounced increase trend has been observed from 1999 to a specific change-point, with a posterior decrease until the end of the series. In order to obtain estimates for the parameters of interest, a Bayesian Markov Chain Monte Carlo (MCMC) simulation procedure using the Gibbs sampler algorithm was developed. The Bayesian model with autoregressive terms of order 1 fits well to the data, allowing to estimate the change-point at July 2007, and probably reflecting the results of the new health policies and previously adopted programs directed toward patients with asthma. The results imply that the present model is useful to analyse the monthly number of dispensed asthma medications and it can be used to describe a broad range of epidemiological time series data where a change-point is present.",2018-06,21/11/2018 10:57,14/04/2020 08:34,,Mar-25,,1,42,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PPUHIKXK,journalArticle,2018,"Xiaodong, Cui; Yuhua, Zheng",Forecasting demand for long-term care based on multistate piecewise constant Markov process,ECONOMIC JOURNAL OF EMERGING MARKETS,,2086-3128,10.20885/ejem.vol10.iss1.art3,,"This paper forecasts demand for long-term care based on multistate piecewise constant Markov process. Two types of data are mainly used in this study. The first type of data came from the Chinese Longitudinal Healthy Longevity Survey (CLHLS), 2008-2011. The second type of data came from the China's Demographic Yearbook of 2016, used as the number of population in the base period. It finds that the changes in health have a significant difference in gender and age. It also finds that under different health states, the distribution of duration of staying in each state in different gender and age groups shows a characteristic similar to the distribution of population size.",2018,21/11/2018 10:57,14/04/2020 08:34,,15-31,,1,10,,,,,,,,,,,,,,,,,,,,,1; Markov; 310,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3TJ2FSGR,journalArticle,2018,"Colvin, Marianna L.; Thompson, Heather; Miller, Shari E.",Comparing Child Maltreatment Prevention and Service Delivery at the Community Level of Practice: A Mixed-Methods Network Analysis,HUMAN SERVICE ORGANIZATIONS MANAGEMENT LEADERSHIP & GOVERNANCE,,2330-3131,10.1080/23303131.2017.1392389,,"Child maltreatment practice has broadened in recent decades to include prevention strategies, however much remains unknown about how preventive efforts are enacted among organizations at the community level compared to service delivery. Using a mixed-methods design with 67 interviews and 80 network surveys, this study compares interactions among organizations across prevention and service domains. Data suggest that though organizations are active in prevention, and view services as preventative, prevention efforts are substantially less defined, relationships around prevention are less mutually recognized, and prevention occurs in a structure of more dispersed rather than centralized connections. Results are discussed for policy and practice relevance.",2018,21/11/2018 10:57,14/04/2020 08:34,,327-344,,3,42,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DAWIWVX7,journalArticle,2018,"Kang, Hyojung; Nembhard, Harriet Black; Ghahramani, Nasrollah; Curry, William",A system dynamics approach to planning and evaluating interventions for chronic disease management,JOURNAL OF THE OPERATIONAL RESEARCH SOCIETY,,0160-5682,10.1057/s41274-017-0279-3,,"Studies have been reported on the applications of systems science to chronic disease management, but few, if any, have concentrated on chronic kidney disease (CKD). We examined the impact of a system dynamics approach to the evaluation of interventions in care of patients with CKD. We developed a stock flow simulation model and a multi-objective goal programming model. After calibrating the model, eight scenarios were analysed to measure intervention effects. Physician education (PE) had the most significant impact on reducing disease progression rate (DPR) from Stage 3 to Stage 4, while care coordination had a substantial impact on decreasing DPR Stage 4 to Stage 5. The addition of either CME or primary care team building to PE led to significant reductions in DPR for patients with Stage 3 CKD. The goal programming model indicated that a growing number of primary care physicians and care managers are needed to manage CKD patients overtime. This study showed that the stock flow model is a potentially powerful tool for supporting informed decision-making for planning and implementing interventions at various phases.",2018,21/11/2018 10:57,14/04/2020 08:34,,987-1005,,7,69,,,,,,,,,,,,,,,,,,,,,System dynamics; 1; 320,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XAUL6YES,journalArticle,2018,"Tracy, Melissa; Cerda, Magdalena; Keyes, Katherine M.",Agent-Based Modeling in Public Health: Current Applications and Future Directions,"ANNUAL REVIEW OF PUBLIC HEALTH, VOL 39",,,,,"Agent-based modeling is a computational approach in which agents with a specified set of characteristics interact with each other and with their environment according to predefined rules. We review key areas in public health where agent-based modeling has been adopted, including both communicable and noncommunicable disease, health behaviors, and social epidemiology. We also describe the main strengths and limitations of this approach for questions with public health relevance. Finally, we describe both methodologic and substantive future directions that we believe will enhance the value of agent-based modeling for public health. In particular, advances in model validation, comparisons with other causal modeling procedures, and the expansion of the models to consider comorbidity and joint influences more systematically will improve the utility of this approach to inform public health research, practice, and policy.",2018,21/11/2018 10:57,14/04/2020 08:35,,77-94,,,39,,,,Annual Review of Public Health,,,,,,,,,,,,,DOI: 10.1146/annurev-publhealth040617-014317,,,,systems science; complex systems; epidemiology; simulation; 1; population health; computer models; 100; Community-based care,,"Fielding, JE and Brownson, RC and Green, LW",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, H7S6WNG7,journalArticle,2018,"Escudero, Eliana; Avendano Ben-Azul, Marcela; Dominguez Cancino, Karen",Clinical simulation and patient safety: integration into the nursing curriculum,SCIENTIA MEDICA,,1806-5562,10.13448/1980-6108.2018.1.28853,,"AIMS: To present the experience of creation, development and results of a nursing curriculum that integrates clinical simulation and patient safety with its challenges and achievements after four generations of graduates. EXPERIENCE DESCRIPTION: The School of Nursing at the Finis Terrae University is the result of a direct request from the authorities of the institution at a time when the country required an increase in the supply of nursing professionals. It started with a project that in the course of its development and implementation require several adjustments in programmatic terms. From its beginning, the project takes into consideration the integration of simulation and sets security at the heart of development. For this, we worked on new instruments that established how to implement the educational process, generating a model of teaching based on simulation, together with the establishment of control points that allowed the application of the model of continuous improvement. Through its development, seals are configured that differentiate the nursing student in the national environment. We are currently working to comply with international standards, periodically reviewing the implemented strategies and the way we teach for the benefit of our students. We consider as challenges the generation of interprofessional work, the strengthening of the teaching staff, and the generation of research, that demonstrate the benefits of having a curriculum for security based on simulation considering our local reality. CONCLUSIONS: The integration of simulation and patient safety in the nursing career curriculum is a challenge that requires the implementation of innovative processes, mobilizing resources of all kinds to achieve the goal. Strengthening leadership. clinical judgment and quality of nursing professionals deserve this kind of change. We believe changes like this in nursing education will enable us to achieve better health outcomes worldwide.",2018,21/11/2018 10:57,14/04/2020 08:34,,,,"1, SI",28,,,,,,,,,,,,,,,,,,,,,110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HFP2MXME,journalArticle,2018,"Chaves, Lenir Aparecida; Jorge, Alzira de Oliveira; Cherchiglia, Mariangela Leal; Reis, Ilka Afonso; da Cunha Santos, Marcos Antonio; Santos, Alaneir de Fatima; Gonzaga da Matta Machado, Antonio Thomaz; Gurgel Andrade, Eli Iola",Integration of primary care in the healthcare network: analysis of the components in the external evaluation of the PMAQ-AB,CADERNOS DE SAUDE PUBLICA,,0102-311X,10.1590/0102-311X00201515,,"This cross-sectional study examined the integration of primary care in the healthcare network of the Brazilian Unified National Health System (SUS), using the Gradual Response Model of Item Response Theory. Based on data from 17,202 teams that participated in the National Program for Access and Quality Improvement in Primary Care (PMAQ-AB, 2012), we measured gradients of integration to identify the teams' profile by level of integration. The results show that the items pertaining to matrix support measures (medical consultations, case discussions, shared clinical action, joint elaboration of therapeutic projects, permanent educational activities, work process discussions, interventions in the territory, and visits with primary care professionals) improved the performance of primary care teams. Communications devices between teams reinforced this understanding. Still, the approximately 50% of answers associated with the worst scenario for some study items evidenced the need to upgrade the integration between primary care activities and specialized care for the consolidation of comprehensive primary healthcare.",2018,21/11/2018 10:57,14/04/2020 08:34,,,,2,34,,,,,,,,,,,,,,,,,,,,,Humans; Quality of Health Care; Quality Improvement; Cross-Sectional Studies; Cooperative Behavior; National Health Programs; Brazil; 00; Health Services Accessibility/organization & administration/*statistics & numerical data; Primary Health Care/organization & administration/*statistics & numerical data; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 85XIGXG7,journalArticle,2018,"Blanks, Thomas; Woodier, Nicholas; Baxendale, Bryn; Fores, Mark; Fullerton, Lynn",A qualitative evaluation of the role of simulation in policy development for service improvement,BMJ SIMULATION & TECHNOLOGY ENHANCED LEARNING,,2056-6697,10.1136/bmjstel-2017-000219,,"Objective To evaluate the efficacy of simulation-based techniques to prospectively assess developing polices prior to implementation. Methods A self-selected sample of nursing staff from a local, acute hospital reviewed a draft intravenous drug administration policy before simulating drug administration of either an infusion or direct injection. The participants completed a postsimulation questionnaire regarding the new policy and simulation, took part in a semistructured interview and were observed during the simulation with their consent. Results 10 staff attended the simulation. The emergent themes identified a wide range of factors relating to the everyday usability and practicalities of the policy. There were issues surrounding inconsistent language between different clinical teams and training requirements for the new policy. Conclusion Simulation, using simple scenarios, allows the safe evaluation of new policies before publication to ensure they are appropriate for front-line use. It engages staff in user-centred design in their own healthcare system.",2018-01,21/11/2018 10:57,14/04/2020 08:34,,19-22,,1,4,,,,,,,,,,,,,,,,,,,,,1; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3QBRUVTX,journalArticle,2018,"Patel, Rupa R.; Luke, Douglas A.; Proctor, Enola K.; Powderly, William G.; Chan, Philip A.; Mayer, Kenneth H.; Harrison, Laura C.; Dhand, Amar",Sex Venue-Based Network Analysis to Identify HIV Prevention Dissemination Targets for Men Who Have Sex with Men,LGBT HEALTH,,2325-8292,10.1089/lgbt.2017.0018,,"Purpose: The aim of this study was to identify sex venue-based networks among men who have sex with men (MSM) to inform HIV preexposure prophylaxis (PrEP) dissemination efforts. Methods: Using a cross-sectional design, we interviewed MSM about the venues where their recent sexual partners were found. Venues were organized into network matrices grouped by condom use and race. We examined network structure, central venues, and network subgroups. Results: Among 49 participants, the median age was 27 years, 49% were Black and 86% reported condomless anal sex (ncAS). Analysis revealed a map of 54 virtual and physical venues with an overlap in the ncAS and with condom anal sex (cAS) venues. In the ncAS network, virtual and physical locations were more interconnected. The ncAS venues reported by Blacks were more diffusely organized than those reported by Whites. Conclusion: The network structures of sex venues for at-risk MSM differed by race. Network information can enhance HIV prevention dissemination efforts among subpopulations, including PrEP implementation.",2018-01,21/11/2018 10:57,14/04/2020 08:35,,78-85,,1,5,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LBLYSVQP,journalArticle,2017,"Lane, Daniel; Beigzadeh, Shima; Moll, Richard",Adaptation Decision Support: An Application of System Dynamics Modeling in Coastal Communities,INTERNATIONAL JOURNAL OF DISASTER RISK SCIENCE,,2095-0055,10.1007/s13753-017-0154-5,,"This research develops and applies a system dynamics (SD) model for the strategic evaluation of environmental adaptation options for coastal communities. The article defines and estimates asset-based measures for community vulnerability, resilience, and adaptive capacity with respect to the environmental, economic, social, and cultural pillars of the coastal community under threat. The SD model simulates the annual multidimensional dynamic impacts of severe coastal storms and storm surges on the community pillars under alternative adaptation strategies. The calculation of the quantitative measures provides valuable information for decision makers for evaluating the alternative strategies. The adaptation strategies are designed model results illustrated for the specific context of the coastal community of Charlottetown, Prince Edward Island, Canada. The dynamic trend of the measures and model sensitivity analyses for Charlottetown-facing increased frequency of severe storms, storm surges, and sea-level rise-provide impetus for enhanced community strategic planning for the changing coastal environment. This research is presented as part of the International Community-University Research Alliance C-Change project “Managing Adaptation to Environmental Change in Coastal Communities: Canada and the Caribbean” sponsored by the Social Science and Humanities Research Council of Canada and the International Development Resource Centre.",2017-12,21/11/2018 10:57,14/04/2020 08:34,,374-389,,4,8,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 943ASHX9,journalArticle,2017,"Comans, T. A.; Chang, A. T.; Standfield, L.; Knowles, D.; O'Leary, S.; Raymer, M.",The development and practical application of a simulation model to inform musculoskeletal service delivery in an Australian public health service,OPERATIONS RESEARCH FOR HEALTH CARE,,2211-6923,10.1016/j.orhc.2017.07.002,,"Timely access to orthopaedic and neurosurgery services in public hospitals is difficult to achieve due to constrained resources and rising demand with the result that waiting time targets are often not met. Advanced physiotherapy-led clinics can assist in managing demand by directly assessing and managing many patients without the need for consultation with a medical specialist. The purpose of this study was to develop and apply simulation modelling to determine the scale and mix of services required to efficiently manage demand from patients with musculoskeletal conditions in one health district. Design We designed a simulation model to estimate service demand over five years and test different service configurations (medical specialist-led or advanced physiotherapy-led) to meet waiting time targets and reduce waiting lists in orthopaedic and neurosurgery services. Results Without intervention, the combined orthopaedic and neurosurgical outpatient waiting list is predicted to grow from 11,000 to over 15,000 patients over a five year period. To achieve waiting time targets within 2 years the scale of services would need to approximately double and the most efficient combination would be to direct approximately 50% of referrals to medical specialist clinics and 50% to advanced physiotherapy-led clinics. Conclusions In the health system modelled, a significant gap was identified between future demand and current provision of services. Simulation modelling was able to assist service planners understand the demand and identify effective management strategies. (C) 2017 Elsevier Ltd. All rights reserved.",2017-12,21/11/2018 10:57,14/04/2020 08:34,,13-18,,,15,,,,,,,,,,,,,,,,,,,,,00; Review,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2WD9G2CC,journalArticle,2017,"Kapp, Julie M.; Simoes, Eduardo J.; DeBiasi, Anne; Kravet, Steven J.",A Conceptual Framework for a Systems Thinking Approach to US Population Health,SYSTEMS RESEARCH AND BEHAVIORAL SCIENCE,,1092-7026,10.1002/sres.2420,,"US health outcomes remain poorer than those of high-income peer countries despite collective efforts directed at improving health and healthcare. Regarding population health, such collective impact efforts increasingly come from community-based organizations, as federal budgets have been cut over the years. The Institute of Medicine recently identified core metrics to facilitate collective efforts and specified the Secretary of Health and Human Services as the position to lead the nation's efforts to improve the health of the population. However, integration across such a complex system requires a clear, deliberate systems approach. We adapt The Malcolm Baldrige Framework for Performance Excellence as a conceptual model with which to apply systems thinking to population health improvement. We offer specific recommendations necessary to build a national systems thinking approach towards improving the health of communities and populations if we hope to ameliorate the US health disadvantage. Copyright (c) 2016 The Authors Systems Research and Behavioral Science published by International Federation for Systems Research and John Wiley & Sons Ltd.",2017-12,21/11/2018 10:57,14/04/2020 08:34,,686-698,,6,34,,,,,,,,,,,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2E3BBUGZ,journalArticle,2017,"Groves, Patricia S.; Bunch, Jacinda L.; Cram, Ellen; Farag, Amany; Manges, Kirstin; Perkhounkova, Yelena; Scott-Cawiezell, Jill",Priming Patient Safety Through Nursing Handoff Communication: A Simulation Pilot Study,WESTERN JOURNAL OF NURSING RESEARCH,,0193-9459,10.1177/0193945916673358,,Understanding how safety culture mechanisms affect nursing safety-oriented behavior and thus patient outcomes is critical to developing hospital safety programs. Safety priming refers to communicating safety values intended to activate patient safety goals. Safety priming through nursing handoff communication was tested as a means by which cultural safety values may affect nursing practice. The mixed-methods pilot study setting was an academic medical center's high-fidelity simulation lab. Twenty nurses were randomized into intervention and control groups. The intervention group received a safety priming intervention; all participants were observed for completing appropriate actions in response to patient safety risks embedded in a scenario. Stimulated recall interviews were conducted following simulation completion. Nurses receiving the safety priming intervention performed slightly but non-significantly more safety actions than nurses who did not (60.5% vs. 57.9% of 43 actions). Implications for both research and practice are discussed for interventions targeting routine versus safety goal-directed nursing actions.,2017-11,21/11/2018 10:57,14/04/2020 08:34,,1394-1411,,11,39,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GXUW56FJ,journalArticle,2017,"Santos, Argelio; Fallah, Nader; Lewis, Rachel; Dvorak, Marcel F.; Fehlings, Michael G.; Burns, Anthony S.; Noonan, Vanessa K.; Cheng, Christiana L.; Chan, Elaine; Singh, Anoushka; Belanger, Lise; Atkins, Derek; Network, RHSCIR",Methodology of the Access to Care and Timing Simulation Model for Traumatic Spinal Cord Injury Care,JOURNAL OF NEUROTRAUMA,,0897-7151,10.1089/neu.2016.4927,,"Despite the relatively low incidence of traumatic spinal cord injury (tSCI), the management and care of persons with tSCI can be resource intensive and complex, spanning multiple phases of care and disciplines. Using a simulation model built with a system level view of the healthcare system allows for prediction of the impact of interventions on patient and system outcomes from injury through to community reintegration after tSCI. As has been previously described, the Access to Care and Timing (ACT) project developed a simulation model for tSCI care using techniques from operations research. The objective of this article is to briefly describe the methodology and the application of the ACT Model, as it was used in several of the articles in this focus issue. The approaches employed in this model provide a framework to look into the complexity of interactions both within and among the different SCI programs, sites, and phases of care.",15/10/2017,21/11/2018 10:57,14/04/2020 08:35,,2843-2847,,20,34,,,,,,,,,,,,,,,,,,,,,100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 237ZC52S,journalArticle,2017,"Sykes, Susie; Baillie, Lesley; Thomas, Beth; Scotter, Judy; Martin, Fiona",Enhancing Care Transitions for Older People through Interprofessional Simulation: A Mixed Method Evaluation,INTERNATIONAL JOURNAL OF INTEGRATED CARE,,1568-4156,10.5334/ijic.3055,,"Introduction: The educational needs of the health and social care workforce for delivering effective integrated care are important. This paper reports on the development, pilot and evaluation of an interprofessional simulation course, which aimed to support integrated care models for care transitions for older people from hospital to home. Theory and methods: The course development was informed by a literature review and a scoping exercise with the health and social care workforce. The course ran six times and was attended by health and social care professionals from hospital and community (n = 49). The evaluation aimed to elicit staff perceptions of their learning about care transfers of older people and to explore application of learning into practice and perceived outcomes. The study used a sequential mixed method design with questionnaires completed pre (n = 44) and post (n = 47) course and interviews (n = 9) 2-5 months later. Results: Participants evaluated interprofessional simulation as a successful strategy. Post-course, participants identified learning points and at the interviews, similar themes with examples of application in practice were: Understanding individual needs and empathy; Communicating with patients and families; Interprofessional working; Working across settings to achieve effective care transitions. Conclusions and discussion: An interprofessional simulation course successfully brought together health and social care professionals across settings to develop integrated care skills and improve care transitions for older people with complex needs from hospital to home.",2017-12,21/11/2018 10:57,14/04/2020 08:35,,,,,17,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JWXN9Q46,journalArticle,2017,"Lam, Sean Shao Wei; Ng, Clarence Boon Liang; Nguyen, Francis Ngoc Hoang Long; Ng, Yih Yng; Ong, Marcus Eng Hock",Simulation-based decision support framework for dynamic ambulance redeployment in Singapore,INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS,,1386-5056,10.1016/j.ijmedinf.2017.06.005,,"Objective: Dynamic ambulance redeployment policies tend to introduce much more flexibilities in improving ambulance resource allocation by capitalizing on the definite geospatial-temporal variations in ambulance demand patterns over the time-of-the-day and day-of-the-week effects. A novel modelling framework based on the Approximate Dynamic Programming (ADP) approach leveraging on a Discrete Events Simulation (DES) model for dynamic ambulance redeployment in Singapore is proposed in this paper. Methods: The study was based on the Singapore's national Emergency Medical Services (EMS) system. Based on a dataset comprising 216,973 valid incidents over a continuous two-years study period from 1 January 2011-31 December 2012, a DES model for the EMS system was developed. An ADP model based on linear value function approximations was then evaluated using the DES model via the temporal difference (TD) learning family of algorithms. The objective of the ADP model is to derive approximate optimal dynamic redeployment policies based on the primary outcome of ambulance coverage. Results: Considering an 8 min response time threshold, an estimated 5% reduction in the proportion of calls that cannot be reached within the threshold (equivalent to approximately 8000 dispatches) was observed from the computational experiments. The study also revealed that the redeployment policies which are restricted within the same operational division could potentially result in a more promising response time performance. Furthermore, the best policy involved the combination of redeploying ambulances whenever they are released from service and that of relocating ambulances that are idle in bases. Conclusion: This study demonstrated the successful application of an approximate modelling framework based on ADP that leverages upon a detailed DES model of the Singapore's EMS system to generate approximate optimal dynamic redeployment plans. Various policies and scenarios relevant to the Singapore EMS system were evaluated.",2017-10,21/11/2018 10:57,14/04/2020 08:34,,37-47,,,106,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KZNANNCK,journalArticle,2017,"Montagna, Sara; Omicini, Andrea",Agent-based modeling for the self-management of chronic diseases: An exploratory study,SIMULATION-TRANSACTIONS OF THE SOCIETY FOR MODELING AND SIMULATION INTERNATIONAL,,0037-5497,10.1177/0037549717712605,,"The impact of mobile technologies on healthcare is particularly evident in the case of self-management of chronic diseases, where they can decrease spending and improve life quality of patients. We propose the adoption of agent-based modeling and simulation techniques as built-in tools to dynamically monitor the state of patient health and provide recommendations for self-management. To demonstrate the feasibility of our proposal we focus on Type 1 diabetes mellitus as our case study, and provide simulation results where the dynamic evolution of signal parameters is shown in the case of healthy and Type 1 diabetes mellitus patients, focussing in particular on the beneficial effects that self-management interventions have on plasma glucose values.",2017-09,21/11/2018 10:57,14/04/2020 08:34,,781-793,,"9, SI",93,,,,,,,,,,,,,,,,,,,,,1; Agent Based; 310,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6P2JBD6R,journalArticle,2017,"Hellier, Susan D.; Ramponi, Denise R.; Wrynn, Alexander; Garofalo, Stephanie",An Innovative Approach Using Simulation to Teach Primary Care Gynecologic Procedures,SIMULATION IN HEALTHCARE-JOURNAL OF THE SOCIETY FOR SIMULATION IN HEALTHCARE,,1559-2332,10.1097/SIH.0000000000000213,,"Introduction: In response to the growing body of evidence that simulation is a satisfactory way to instruct procedural skills, we developed an innovative model to teach common gynecologic procedures such as cervical cancer screening, cervical polyp removal, intrauterine device removal, and endometrial biopsy. The objectives of this study were to describe the construction of the model and to assess participants' satisfaction and confidence in applying the learning objectives to their clinical practice. Methods: The researchers created the model with reusable and readily available materials. During a hands-on skills workshop, practicing clinicians performed simulated cervical cancer screening, endocervical polyp removal, intrauterine device removal, and an endometrial biopsy on a low-fidelity gynecologic model. Using convenience sampling, each participant completed a survey designed to measure satisfaction with the workshop and self-confidence in their newly acquired skills. Results: All (N=30,100%) of the participants agreed at the “agree” or “strongly agree” level that the gynecologic skills workshop using lecture and a hands-on model was a satisfying and self-confidencebuilding experience. Conclusions: An easily reproducible and reusable gynecologic procedure simulator was highly rated as a means of teaching common primary care gynecologic procedures. The simulated model provided an opportunity for hands-on skills learning for clinicians who wish to expand their gynecologic procedure skill set.",2017-08,21/11/2018 10:57,14/04/2020 08:34,,268-273,,4,12,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8WVIWRXI,journalArticle,2017,"Tetuan, Theresa; Ohm, Ruth; Kinzie, Lenora; McMaster, Shelly; Moffitt, Brenda; Mosier, Michael",Does Systems Thinking Improve the Perception of Safety Culture and Patient Safety?,JOURNAL OF NURSING REGULATION,,2155-8256,10.1016/S2155-8256(17)30096-0,,"Introduction: Adverse patient events are frequently associated with medication administration errors. Despite implementation of barcode technology, medication administration errors continue, often because of system issues. Integrating systems thinking into nursing practice facilitates identification and correction of factors that interfere with patient safety. Safety culture is positively associated with patient outcomes. The purpose of this study was to improve patient safety with respect to medication administration through an intervention designed to enhance systems thinking (Systems Thinking Education Program, STEP). Aims: Specific aims were to identify nurse workarounds during medication administration, to assess changes in the rates of medication events and workarounds after STEP, to assess changes in systems thinking and safety culture after STEP, and to correlate safety culture and systems thinking. Methods: This study was a pre-post comparison with a STEP intervention (including medication huddles) and organization-wide monthly education for 1 year. Outcome measures included perception of safety culture, as measured by the Safety Attitudes Questionnaire, and systems thinking, as measured by the Systems Thinking Scale. All organization nurses were invited to complete preintervention and postintervention electronic surveys via an e-mail link. Additionally, medication event rates and workaround rates were determined by direct medication administration observations on eight units (six inpatient and two ambulatory) that were conducted before and after intervention with trained data collectors. Results: A total of 1,652 medication observations before intervention and 1,998 observations after intervention were reported. The workaround rate was significantly lower after STEP (175 workarounds out of 1,998 observations; 8.8%) compared with before (305 workarounds out of 1,652 observations; 18.5%), p < .0001. The rate of medication events also decreased from 9.4% (156 of 1,652 observations) before intervention vs. 4.2% (84 of 1,998 observations) after intervention (p < .0001). The survey response rate was 40% (n = 585) before and 23% (n = 334) after intervention. The nurses' perception of safety culture was more positive after the systems thinking program compared with before the program (p = .029). Similarly, the systems thinking scores were higher after intervention compared with before intervention (p = .013). Scores on the Safety Attitudes Questionnaire and Systems Thinking Scale were positively correlated (r = .297, p < .001). Medication timing with food and rate of intravenous fluid pushes were identified as problematic. Conclusion: The STEP intervention strengthened understanding of systems thinking and revealed the importance of addressing the nurse as a second victim of medication errors, which is likely to be central to safety culture for nurses. Medication huddles may be a useful intervention to improve systems thinking.",2017-07,21/11/2018 10:57,14/04/2020 08:35,,31-39,,2,8,,,,,,,,,,,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CXD3HCS2,journalArticle,2017,"Freytag, Julia; Stroben, Fabian; Hautz, Wolf E.; Eisenmann, Dorothea; Kaemmer, Juliane E.","Improving patient safety through better teamwork: how effective are different methods of simulation debriefing? Protocol for a pragmatic, prospective and randomised study",BMJ OPEN,,2044-6055,10.1136/bmjopen-2017-015977,,"Introduction Medical errors have an incidence of 9% and may lead to worse patient outcome. Teamwork training has the capacity to significantly reduce medical errors and therefore improve patient outcome. One common framework for teamwork training is crisis resource management, adapted from aviation and usually trained in simulation settings. Debriefing after simulation is thought to be crucial to learning teamwork-related concepts and behaviours but it remains unclear how best to debrief these aspects. Furthermore, teamwork-training sessions and studies examining education effects on undergraduates are rare. The study aims to evaluate the effects of two teamwork-focused debriefings on team performance after an extensive medical student teamwork training. Methods and analyses A prospective experimental study has been designed to compare a well-established three-phase debriefing method (gather-analyse-summarise; the GAS method) to a newly developed and more structured debriefing approach that extends the GAS method with TeamTAG (teamwork techniques analysis grid). TeamTAG is a cognitive aid listing preselected teamwork principles and descriptions of behavioural anchors that serve as observable patterns of teamwork and is supposed to help structure teamwork-focused debriefing. Both debriefing methods will be tested during an emergency room teamwork-training simulation comprising six emergency medicine cases faced by 35 final-year medical students in teams of five. Teams will be randomised into the two debriefing conditions. Team performance during simulation and the number of principles discussed during debriefing will be evaluated. Learning opportunities, helpfulness and feasibility will be rated by participants and instructors. Analyses will include descriptive, inferential and explorative statistics. Ethics and dissemination The study protocol was approved by the institutional office for data protection and the ethics committee of Charite Medical School Berlin and registered under EA2/172/16. All students will participate voluntarily and will sign an informed consent after receiving written and oral information about the study. Results will be published.",2017-06,21/11/2018 10:57,14/04/2020 08:34,,,,6,7,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FKFNBRX8,journalArticle,2017,"Lorca, Alvaro; Celik, Melih; Ergun, Ozlem; Keskinocak, Pinar",An Optimization-Based Decision-Support Tool for Post-Disaster Debris Operations,PRODUCTION AND OPERATIONS MANAGEMENT,,1059-1478,10.1111/poms.12643,,"Debris generated by disasters can hinder relief efforts and result in devastating economic, environmental, and health problems. In this study, we present a decision-support tool employing analytical models to assist disaster and waste management officials with decisions regarding collection, transportation, reduction, recycling, and disposal of debris. The tool enables optimizing and balancing the financial and environmental costs, duration of the collection and disposal operations, landfill usage, and the amount of recycled materials. In addition to post-disaster operational decisions, the tool can also support the challenging task of developing strategic plans for disaster preparedness. We illustrate the applicability and effectiveness of the tool with a disaster scenario based on Hurricane Andrew.",2017-06,21/11/2018 10:57,14/04/2020 08:34,,1076-1091,,"6, SI",26,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KAH8EYH4,journalArticle,2017,"Sampaio, Ricardo B.; Fonseca, Bruna P. F.; Bahulkar, Ashwin; Szymanski, Boleslaw K.",Network analysis to support public health: evolution of collaboration among leishmaniasis researchers,SCIENTOMETRICS,,0138-9130,10.1007/s11192-017-2346-6,,"Databases on scientific publications are a well-known source for complex network analysis. The present work focuses on tracking evolution of collaboration amongst researchers on leishmaniasis, a neglected disease associated with poverty and very common in Brazil, India and many other countries in Latin America, Asia and Africa. Using SCOPUS and PubMed databases we have identified clusters of publications resulting from research areas and collaboration between countries. Based on the collaboration patterns, areas of research and their evolution over the past 35 years, we combined different methods in order to understand evolution in science. The methods took into consideration descriptive network analysis combined with lexical analysis of publications, and the collaboration patterns represented by links in network structure. The methods used country of the authors' publications, MeSH terms, and the collaboration patterns in seven five-year period collaboration network and publication networks snapshots as attributes. The results show that network analysis metrics can bring evidences of evolution of collaboration between different research groups within a specific research area and that those areas have subnetworks that influence collaboration structures and focus.",2017-06,21/11/2018 10:57,14/04/2020 08:35,,2001-2021,,3,111,,,,,,,,,,,,,,,,,,"

6th Global Tech Mining Conference, Valencia, SPAIN, SEP, 2016

",,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 623ICXJS,journalArticle,2017,"Yang, Bai",Research on the Optimization of Public Health Communication and Public Health Behavior,AGRO FOOD INDUSTRY HI-TECH,,1722-6996,,,"With the rapid development of the economy, the ecological environment has been repeatedly damaged. Many diseases have been brought to mankind. People are busy working hard and neglecting the health problems. Therefore, the health management of the whole people needs to be carried out. In this paper, the basic principles of medicine, psychology, sociology and other disciplines were applied. The concept of public health was combined. The current status of public health and existing problems were pointed out. The factors that influence public health behavior were analyzed. Western theories and practices of optimizing health behaviors were combined. Their opinions and strategies for optimizing public health behaviors were proposed, which made a contribution to enhance the spread of universal health, and optimize public health behavior, so that the people have a good fitness habit to improve the physical quality.",2017-06,21/11/2018 10:57,14/04/2020 08:35,,199-203,,3,28,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, A7JQD7CY,journalArticle,2017,"Jeffries, Mark; Phipps, Denham; Howard, Rachel L.; Avery, Anthony; Rodgers, Sarah; Ashcroft, Darren",Understanding the implementation and adoption of an information technology intervention to support medicine optimisation in primary care: qualitative study using strong structuration theory,BMJ OPEN,,2044-6055,10.1136/bmjopen-2016-014810,,"Objectives Using strong structuration theory, we aimed to understand the adoption and implementation of an electronic clinical audit and feedback tool to support medicine optimisation for patients in primary care. Design This is a qualitative study informed by strong structuration theory. The analysis was thematic, using a template approach. An a priori set of thematic codes, based on strong structuration theory, was developed from the literature and applied to the transcripts. The coding template was then modified through successive readings of the data. Setting Clinical commissioning group in the south of England. Participants Four focus groups and five semi-structured interviews were conducted with 18 participants purposively sampled from a range of stakeholder groups (general practitioners, pharmacists, patients and commissioners). Results Using the system could lead to improved medication safety, but use was determined by broad institutional contexts; by the perceptions, dispositions and skills of users; and by the structures embedded within the technology. These included perceptions of the system as new and requiring technical competence and skill; the adoption of the system for information gathering; and interactions and relationships that involved individual, shared or collective use. The dynamics between these external, internal and technological structures affected the adoption and implementation of the system. Conclusions Successful implementation of information technology interventions for medicine optimisation will depend on a combination of the infrastructure within primary care, social structures embedded in the technology and the conventions, norms and dispositions of those utilising it. Future interventions, using electronic audit and feedback tools to improve medication safety, should consider the complexity of the social and organisational contexts and how internal and external structures can affect the use of the technology in order to support effective implementation.",2017-05,21/11/2018 10:57,14/04/2020 08:34,,,,5,7,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LYG99WX5,journalArticle,2017,"Fitzpatrick, Scott J.; Hooker, Claire",A `systems' approach to suicide prevention: radical change or doing the same things better?,PUBLIC HEALTH RESEARCH & PRACTICE,,2204-2091,10.17061/phrp2721713,,"Suicide is a significant public health concern. Continued high suicide rates, coupled with emerging international evidence, have led to the development of a `systems' approach to suicide prevention, which is now being trialled as part of a proposed Suicide Prevention Framework for NSW (New South Wales, Australia). The Framework replicates successful international approaches. It is organised around nine components, ranging from individual to population-level approaches, to improve coordination and integration of existing services. If implemented fully, the Framework may lead to a significant reduction in suicide. However, to ensure its long-term success, we must attend to underlying structures within the system and their interrelationships. Such an approach will also ensure that policy makers and local suicide prevention action groups, particularly in rural areas, are able to respond to local challenges and incorporate multiple perspectives into their practice, including evidence for the broader social determinants of suicide.",2017-04,21/11/2018 10:57,14/04/2020 08:34,,,,2,27,,,,,,,,,,,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7LECSRTR,journalArticle,2017,"Buti, Maria; Luis Calleja, Jose; Garcia-Samaniego, Javier; Angel Serra, Miguel; Crespo, Javier; Romero, Manuel; Angel Simon, Miguel; Turnes, Juan; Javier Blasco, Antonio; Lazaro, Pablo; Robbins, Sarah; Razavi, Homie; Estudi, Representacion Grp",Elimination of hepatitis C in Spain: Adaptation of a mathematical model based on the public health strategic plan for addressing hepatitis C in the National Health System,MEDICINA CLINICA,,0025-7753,10.1016/j.medcli.2016.12.018,,,22/03/2017,21/11/2018 10:57,14/04/2020 08:34,,277-282,,6,148,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FGECSR3Y,journalArticle,2017,"Wiler, Jennifer L.; Bookman, Kelly; Birznieks, Derek B.; Leeret, Robert; Koehler, April; Planck, Shauna; Zane, Richard",Rapid Process Optimization: A Novel Process Improvement Methodology to Innovate Health Care Delivery,AMERICAN JOURNAL OF MEDICAL QUALITY,,1062-8606,10.1177/1062860616637683,,"Health care systems have utilized various process redesign methodologies to improve care delivery. This article describes the creation of a novel process improvement methodology, Rapid Process Optimization (RPO). This system was used to redesign emergency care delivery within a large academic health care system, which resulted in a decrease: (1) door-to-physician time (Department A: 54 minutes pre vs 12 minutes 1 year post; Department B: 20 minutes pre vs 8 minutes 3 months post), (2) overall length of stay (Department A: 228 vs 184; Department B: 202 vs 192), (3) discharge length of stay (Department A: 216 vs 140; Department B: 179 vs 169), and (4) left without being seen rates (Department A: 5.5% vs 0.0%; Department B: 4.1% vs 0.5%) despite a 47% increased census at Department A (34391 vs 50691) and a 4% increase at Department B (8404 vs 8753). The novel RPO process improvement methodology can inform and guide successful care redesign.",2017-04,21/11/2018 10:57,14/04/2020 08:35,,172-177,,2,32,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FHM25QLM,journalArticle,2017,"Kostopoulou, Olga; Porat, Talya; Corrigan, Derek; Mahmoud, Samhar; Delaney, Brendan C.",Diagnostic accuracy of GPs when using an early-intervention decision support system: a high-fidelity simulation,BRITISH JOURNAL OF GENERAL PRACTICE,,0960-1643,10.3399/bjgp16X688417,,"Background Observational and experimental studies of the diagnostic task have demonstrated the importance of the first hypotheses that come to mind for accurate diagnosis. A prototype decision support system (DSS) designed to support GPs' first impressions has been integrated with a commercial electronic health record (EHR) system. Aim To evaluate the prototype DSS in a high-fidelity simulation. Design and setting Within-participant design: 34 GPs consulted with six standardised patients (actors) using their usual EHR. On a different day, GPs used the EHR with the integrated DSS to consult with six other patients, matched for difficulty and counterbalanced. Method Entering the reason for encounter triggered the DSS, which provided a patient-specific list of potential diagnoses, and supported coding of symptoms during the consultation. At each consultation, GPs recorded their diagnosis and management. At the end, they completed a usability questionnaire. The actors completed a satisfaction questionnaire after each consultation. Results There was an 8-9% absolute improvement in diagnostic accuracy when the DSS was used. This improvement was significant (odds ratio [OR] 1.41, 95% confidence interval [CI] = 1.13 to 1.77, P<0.01). There was no associated increase of investigations ordered or consultation length. GPs coded significantly more data when using the DSS (mean 12.35 with the DSS versus 1.64 without), and were generally satisfied with its usability. Patient satisfaction ratings were the same for consultations with and without the DSS. Conclusion The DSS prototype was successfully employed in simulated consultations of high fidelity, with no measurable influences on patient satisfaction. The substantially increased data coding can operate as motivation for future DSS adoption.",2017-03,21/11/2018 10:57,14/04/2020 08:34,,E201-E208,,656,67,,,,,,,,,,,,,,,,,,,,,"Humans; Adult; Female; Male; Middle Aged; Young Adult; Reproducibility of Results; Aged; Computer Simulation; Electronic Health Records; Quality Improvement; United Kingdom; *Decision Support Systems, Clinical; 1; *electronic health record; *decision support systems; *diagnosis; *Diagnosis, Computer-Assisted; *diagnostic accuracy; *diagnostic errors; *Early Diagnosis; *first impressions; *general practice; Diagnostic Errors/*prevention & control; General Practice/*methods/standards; Referral and Consultation/standards; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5PNJQKSS,journalArticle,2017,"Vercruysse, Sien; De Clercq, Dirk; Goossens, Lennert; Aelterman, Nathalie; Haerens, Leen",Development and optimization of an injury prevention intervention for physical education teachers,PHYSICAL EDUCATION AND SPORT PEDAGOGY,,1740-8989,10.1080/17408989.2016.1165192,,"Background: Injury prevention is highly needed in physically active populations, such as pre-service and in-service physical education teachers (PETs). As a lack of adherence to preventive strategies is problematic in injury, it seems crucial to develop and optimize interventions that correspond to the specific needs and wishes of PETs.Aim: The purpose of the present study was fourfold. Specifically, we aimed at (1) systematically optimizing an injury prevention intervention for PETs, based on teachers' qualitative evaluation of the intervention, (2) quantitatively investigating whether the appreciation of the injury prevention intervention was higher after optimization, (3) examining whether participation in the intervention resulted in positive changes in teachers' perceived utility of, and confidence to apply the proposed preventive strategies, as well as their knowledge about these strategies, and (4) describing teachers' adherence to the proposed preventive strategies while they were engaging in the intervention.Participants: Twenty PETs (13 men, Mage = 42.1 12.17 years) from nine different secondary schools in Flanders (Belgium) voluntarily participated in this study. The intervention, based on findings from the continuing professional development (CPD) literature, and the principles of the self-determination theory, took place on two different training days (Training A and Training B) and consisted of seven intrinsic injury prevention strategies.Data collection and analysis: Qualitative data on teachers' appreciation of the intervention were collected by means of focus group interviews, which were used to optimize the intervention (Aim 1). Quantitative data on teachers' appreciation were collected directly after they had engaged in the intervention and were used to compare the appreciation from the initial to more optimized versions of the trainings (Aim 2). Further, by means of repeated measures ANOVAs positive evolutions in teachers' belief in the utility of, confidence to apply and knowledge about the provided strategies across time were examined (Aim 3). Finally, teachers' adherence was evaluated by relying on weekly online registrations of minutes and types of preventive strategies teachers had practised during the past week (Aim 4).Findings: Despite the relatively high initial appreciation scores (4.2 out of 5), the optimized versions of the trainings scored better on interaction, intelligibility, innovation, practical usefulness, and recommendation (Aims 1 and 2). Significant differences were found over time in terms of within-teacher changes in perceived utility of (4.05-4.73-4.48; p<.001), confidence to apply (3.75-3.96-4.26; p<.001) and knowledge about preventive strategies (2.49-3.53-3.39; p<.001; Aim 3). Finally, prospective registrations of teachers' adherence to the proposed strategies showed a mean time of 62.1 +/- 48.6 min/week with a balanced distribution of the different strategies (Aim 4).Conclusions: The present study developed an intervention that optimally fulfils the wishes and needs of the target population, namely PETs, and can readily be implemented in PET education programmes or CPD programmes for in-service PETs. Results of this pilot study are promising because teachers displayed increases in several relevant outcomes. Various suggestions are formulated on how to increase PETs' appreciation of CPD programmes.",2017-03,21/11/2018 10:57,14/04/2020 08:35,,171-186,,2,22,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CQR8AS26,journalArticle,2017,"Cumin, David; Skilton, Carmen; Weller, Jennifer",Information transfer in multidisciplinary operating room teams: a simulation-based observational study,BMJ QUALITY & SAFETY,,2044-5415,10.1136/bmjqs-2015-005130,,"Background Communication of clinically relevant information between members of the operating room (OR) team is critical for safe patient care. Formal communication processes, such as briefing, sign in and time out, are designed to promote this. Aims We investigated patterns of communication of clinically relevant information between OR staff in simulated surgical scenarios, to identify factors associated with effective information sharing. We focused on the influence of precase briefing, sign in and time out, which we defined as formal team communications. Method Twenty teams of six participated in two scenarios during a day-long course. Participants each received unique, clinically relevant items of information (information probes) prior to simulations and were tested postscenario on recall of the information in the probe. Using videos of the simulations, we coded each time an information probe was mentioned against a structured framework. Results Of the 145 instances where a probe was mentioned at least once, 75 (51.7%) were mentioned during a formal team communication. However, there were 89 instances of a possible 234 (38%) where a probe was never mentioned. Some team members were more likely to mention the information than others. When probes were mentioned during formal team communications, significantly more team members were attentive (1.4 vs 2.3; p<0.001), the information was significantly more likely to be recalled and the team was five times more likely (p=0.01) to recall the information than if the information was only mentioned outside of a formal communication. Conclusions While our study supports the value of formal team communications during precase briefing, sign in and time out in the Surgical Safety Checklist, our findings suggest suboptimal transmission of information between team members and unequal contributions of information by different professional groups.",2017-03,21/11/2018 10:57,14/04/2020 08:34,,209-216,,3,26,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 69CRIFMT,journalArticle,2017,"Colvin, Marianna L.",Mapping the inter-organizational landscape of child maltreatment prevention and service delivery: A network analysis,CHILDREN AND YOUTH SERVICES REVIEW,,0190-7409,10.1016/j.childyouth.2017.01.003,,"Network analysis is uniquely suited to inform the complex interactions in contemporary child welfare practice. This study examined the community-wide interconnectivity of child welfare efforts that exist across organizations in a county system. Structural properties were measured for 11 activities, including sending/receiving referrals, case coordination, shared resources, education/awareness, fundraising, and evaluation. The sample was bounded to match the county-level implementation of local child welfare services and to emphasize the complex context in which organizations implement social interventions. Eighty organizations participated in a network survey and findings systematically quantify the breadth and degree of their interdependence, thus making a distinct contribution to the field's understanding of multidisciplinary participation and collective action. Differences in network cohesion across types of activities, including a dominance of referrals and a relative absence of fundraising and evaluation relationships, are discussed for policy and practice relevance, as are directions for future systematic network research in child welfare settings. (C) 2017 Elsevier Ltd. All rights reserved.",2017-02,21/11/2018 10:57,14/04/2020 08:34,,352-359,,,73,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Y54D8KMP,journalArticle,2017,"Turkelson, Carman; Keiser, Megan",Using Checklists and Repetitive Simulation to Improve Patient Safety: A Pilot Project with the Impella (R) Left Ventricular Assist Device,CLINICAL SIMULATION IN NURSING,,1876-1399,10.1016/j.ecns.2016.10.009,,"Background: Low-frequency, high-risk patients in a cardiac intensive care unit have a greater risk for medical errors with serious clinical consequences. Patients with an Impella (R) left-ventricular assist device were chosen as representative of this population. Methods: This project involved the development and implementation of two specialized crisis check-lists with repetitive simulation sessions for patients with an Impella (R) left ventricular assist device. Participants included 26 cardiac intensive care unit nurses who were identified as Impella (R) superusers. Evaluation measures included nursing performance, patient and manikin outcomes, self-confidence, and self-efficacy. Results: The participants were found to have improved adherence to critical processes of care and reduced errors in management of patients with an Impella (R) left ventricular assist device in simulated as well as actual patient events. Conclusion: The results while limited due to small sample size do provide support for the use of safety checklists in combination with repetitive simulations to improve adherence to critical safety practices as well as self-confidence for low-frequency high-risk patients. (c) 2017 International Nursing Association for Clinical Simulation and Learning. Published by Elsevier Inc. All rights reserved.",2017-02,21/11/2018 10:57,14/04/2020 08:35,,53-63,,2,13,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8BPB72Q9,journalArticle,2017,"Dehghanimohammadabadi, Mohammad; Keyser, Thomas K.",Intelligent simulation: Integration of SIMIO and MATLAB to deploy decision support systems to simulation environment,SIMULATION MODELLING PRACTICE AND THEORY,,1569-190X,10.1016/j.simpat.2016.08.007,,"Discrete-event simulation is a decision support tool which enables practitioners to model and analyze their own system behavior. Although simulation packages are capable of mimicking most tasks in a real-world system, there are some decision-making activities, which are beyond the reach of simulation packages. The Application Programmers Interface (API) of SIMIO provides a wide range of opportunities for researchers to develop their own logic and apply it during the simulation run. This paper illustrates how to deploy MAT LAB, as a computational tool coupled with SIMIO, as a simulation package by using a new user-defined step instance named “CallMATLAB”. A manufacturing system case study is introduced where the CallMATLAB step instance is used to create an Iterative Optimization based Simulation (IOS) model. This model is created to evaluate the performance of different optimizers. The benefits of this hybridization for other industries, including healthcare systems, supply chain management systems, and project management problems are discussed. (C) 2016 Elsevier B.V. All rights reserved.",2017-02,21/11/2018 10:57,14/04/2020 08:34,,45-60,,,71,,,,,,,,,,,,,,,,,,,,,00; ******To read; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7C8NSCUY,conferencePaper,2017,"Franck, Thomas; Augusto, Vincent; Xie, Xiaolan; Gonthier, Regis",An optimization-simulation approach for long term care structure assignment problem for elderly people,2017 13TH IEEE CONFERENCE ON AUTOMATION SCIENCE AND ENGINEERING (CASE),978-1-5090-6781-7,,,,"The growing number of elderly people is one of the most important problems for the next years. This part of the population is often dependent and does not tolerate environment changes so that long term care structure assignment should be well prepared. This paper proposes a new optimization-simulation approach to (i) solve the long term care structure assignment problem for a population of elderly people and (ii) validate and calibrate the model depending on stakeholders objectives and territory special features. A Mixed-Integer Linear Program is proposed to solve the tactical assignment problem, while a stochastic simulation is used to assess the key performance indicators relevant for elderly on the long term.",2017,21/11/2018 10:57,14/04/2020 08:34,,574-579,,,,,,,IEEE International Conference on Automation Science and Engineering,,,,IEEE,,,,,,,,,,"

13th IEEE Conference on Automation Science and Engineering (IEEE CASE), Xian, PEOPLES R CHINA, AUG 20-23, 2017

",,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MVVRIAU4,conferencePaper,2017,"Kisliakovskii, Ilia; Balakhontceva, Marina; Kovalchuk, Sergey; Zvartau, Nadezhda; Konradi, Alexandra",Towards a simulation-based framework for decision support in healthcare quality assessment,"6TH INTERNATIONAL YOUNG SCIENTIST CONFERENCE ON COMPUTATIONAL SCIENCE, YSC 2017",,,10.1016/j.procs.2017.11.178,,"This article describes a simulation framework for healthcare quality assessment from the perspective of management and corresponding decision-makers. The proposed framework will allow simulating “what-it” scenarios and getting alternative outcomes in case of decision support systems. In our research, we are dealing with heterogeneous data sources, which combine within data-flow processes. The data flow of the presented framework conceptually combines several modeling methods: discrete-event simulation, agent-based modeling and also includes data analysis. The experiments were executed based on data from the Almazov National Medical Research Centre hospital information and access control systems. (C) 2018 The Authors. Published by Elsevier B.V.",2017,21/11/2018 10:57,14/04/2020 08:34,,207-214,,,119,,,,Procedia Computer Science,,,,Univ Amsterdam,,,,,,,,,,"

6th Annual International Young Scientists Conference on HPC and Computational Science (YSC), Kotka, FINLAND, NOV 01-03, 2017

",,,00; 100,,"Klimova, A and Bilyatdinova, A and Kortelainen, J and Boukhanovsky, A",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EPK3THMF,journalArticle,2017,"Ezisi, Chinyere Nkemdilim; Eze, Boniface Ikenna; Okoye, Obiekwe; Chuka-Okosa, Chimdi Memnofu; Shiweobi, Jude Obinna",Challenges in horizontal integration of eye care services into the pre-existing rural primary care structure: an operations research perspective from Nigeria,FAMILY MEDICINE AND PRIMARY CARE REVIEW,,1734-3402,10.5114/fmpcr.2017.70811,,"Background. The provision of population-wide, accessible, affordable, acceptable and evenly distributed qualitative eye care services remains a recurrent challenge to eye care organizations worldwide. Objectives. To report the challenges encountered in setting up eye care service in a pre-existing primary health care facility in rural Nigeria and also audit the common causes of eye disorders in rural setting southeast of Nigeria. Material and methods. The study was an operations research study conducted at Akpuoga-Nike between February and April 2011. Demographic and ophthalmic clinical data were collected. Health system-, community- and patient-determined challenges were catalogued and analyzed using Epi Info Statistical software for Windows, version 6. Univariate analysis was performed for data distribution testing. Analytical statistics were performed, with p < 0.05 considered statistically significant. Results. A total of 481 (males, 144 (29.9%); females, 377(70.1%)) patients aged 42.3 +/- 20.2 SD years (range 4-80 years) were seen. The leading eye disorders were refractive error - 28.9%, and cataract - 16.4%. The operations challenges encountered included difficulties with community sensitization/advocacies, inadequate infrastructure and mobile equipment, as well as lack of eye care manpower, consumables and funding deficits. Conclusions. Health system-related issues were the main challenges encountered. Recruitment of an adequate number of rural eye care workforce, provision of needed material resources, adequate funding and engendering community participation in rural eye care delivery through grass roots advocacy and health service public education would overcome the challenges.",2017,21/11/2018 10:57,14/04/2020 08:34,,366-371,,4,19,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LDSMJIFJ,conferencePaper,2017,"Asgari, Zeynab; Rahimian, Farzad Pour",Advanced Virtual Reality Applications and Intelligent Agents for Construction Process Optimisation and Defect Prevention,"CREATIVE CONSTRUCTION CONFERENCE 2017, CCC 2017",,,10.1016/j.proeng.2017.08.070,,"Defects and errors in new or recently completed construction work continually pervade the industry. Whilst inspection and monitoring processes are established vehicles for their `control', the procedures involved are often process driven, time consuming, and resource intensive. Paradoxically therefore, they can impinge upon the broader aspects of project time, cost and quality outcomes. Acknowledging this means appreciating concatenation effects such as the potential for litigation, impact on other processes and influence on stakeholders' perceptions-that in turn, can impede progress and stifle opportunities for process optimisation or innovation. That is, opportunities relating to for example, logistics, carbon reduction, health and safety, efficiency, asset underutilisation and efficient labour distribution. This study evaluates these kinds of challenge from a time, cost and quality perspective, with a focus on identifying opportunities for process innovation and optimisation. It reviews-within the construction domain-state of the art technologies that support optimal use of artificial intelligence, cybernetics and complex adaptive systems. From this, conceptual framework is proposed for development of real-time intelligent observational platform supported by advanced intelligent agents, presented for discussion. This platform actively, autonomously and seamlessly manages intelligent agents (Virtual Reality cameras, Radio-Frequency Identification RFID scanners, remote sensors, etc.) in order to identify, report and document `high risk' defects. Findings underpin a new ontological model that supports ongoing development of a dynamic, self-organised sensor (agent) network, for capturing and reporting real-time construction site data. The model is a `stepping stone' for advancement of independent intelligent agents, embracing sensory and computational support, able to perform complicated (previously manual) tasks that provide optimal, dynamic, and autonomous management functions. (c) 2017 The Authors. Published by Elsevier",2017,21/11/2018 10:57,14/04/2020 08:34,,1130-1137,,,196,,,,Procedia Engineering,,,,,,,,,,,,,,"

6th Creative Construction Conference (CCC), Primosten, CROATIA, JUN 19-22, 2017

",,,00; 100,,"Hajdu, M and Skibniewski, ME",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GRBCWXGD,journalArticle,2017,"Korshever, Natan G.; Sidelnikov, Sergei A.",Intersectoral cooperation in the sphere of public health care: ways of optimization,RUSSIAN OPEN MEDICAL JOURNAL,,2304-3415,10.15275/rusomj.2017.0308,,"The aim of the work was to investigate intersectoral cooperation in the sphere of public health care and to substantiate technologies of its optimization. Material and Methods - There were analyzed the normative legal field of public health care, the results of anonymous survey of 838 physicians - health care organizers including 34 experts, and of 6,106 persons not engaged in medical professions. Results - There were established the list and significance of 37 health determinants; the effect produced on them by 23 state and public sectors engaged in health care; characteristics of these sectors' interaction. There were substantiated 38 informative vectors for evaluating the effectiveness of intersectoral cooperation in the sphere of public health care - 22 simple (each representing a single informative criterion) and 16 complex (consisting of several, from 3 to 12) informative criteria. There was developed an automatic multi-vector method for assessing success in intersectoral cooperation in the sphere of public health care in a territorial formation (formations), and there was designed an appropriate technology of optimization, including the primary multi-vector analysis, purposeful correction and dynamic evaluation. Conclusion - Public health care optimization is a process which should be carried out with regard to hierarchic interaction of the engaged sectors and peculiarities of their influence on health determinants, multi-vector evaluation of intersectoral cooperation efficacy aimed to substantiate and choose such administrative decisions which prove to be the best from the viewpoint of resulting effective achievements. The obtained materials may be realized in everyday practice of public health care.",2017,21/11/2018 10:57,14/04/2020 08:34,,,,3,6,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QPWCBZTJ,conferencePaper,2017,"Zhene, Kuan; Liu, Jun; Zhang, Jin-Fang; Hao, Weihua",Assessment method for the prevention effectiveness of PM2.5 based on the optimization development of coal-fired power generation,INTERNATIONAL CONFERENCE ON ENERGY ENGINEERING AND ENVIRONMENTAL PROTECTION (EEEP2016),,,10.1088/1755-1315/52/1/012076,,"A large number of combustion of coal is easy to lead to the haze weather which has brought a lot of inconveniences and threat to people's living and health in E&C China, as the dominant power source of China, the coal-fired power generation is one of the main sources to the haze. In this paper, the contribution of the combustion of coal and development of coal-fired power generation to the PM2.5 emissions is summarized based on the analysis of the present situation, the mechanism and the emission source of PM2.5. Considering the peak of carbon emissions and the constraints of atmospheric environment, the quantitative assessment method of PM2.5 by optimizing the development of coal-fired power generation is present. By the computation analysis for different scenarios, it indicates that the optimization scenario, which means the main new-installed coal-fired power generation is distributed in western and northern China, can prevent the PM2.5 effectively for both the load center and coal base regions of China. The results of this paper not only have reference value for the optimized layout of coal-fired power generation in the “13rd fifth-year” power planning, also is of great significance to deal with problems that the atmospheric pollution and climate warming in the future",2017,21/11/2018 10:57,14/04/2020 08:35,,,,,52,,,,IOP Conference Series-Earth and Environmental Science,,,,,,,,,,,,,,"

International Conference on Energy Engineering and Environmental Protection (EEEP), Sanya, PEOPLES R CHINA, NOV 21-23, 2016

",,,00; 100,,"Huang, KL and Kim, KW and Liu, J",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ULX6LSMR,journalArticle,2017,"Berard, Celine; Cloutier, L. Martin; Cassivi, Luc",The effects of using system dynamics-based decision support models: testing policy-makers' boundaries in a complex situation,JOURNAL OF DECISION SYSTEMS,,1166-8636,10.1080/12460125.2016.1204212,,"Systems thinking and computer-based modelling systems are widely recognised as effective for solving complex problems, particularly for the potential changes they can trigger in decision-makers' perception of where problems' boundaries lie. Surprisingly, few studies have analysed their empirical effects on decision-making. This paper explores the effects of the use of a system dynamics-based decision support system (DSS) by decision-makers, focusing on boundary judgements, which indicate what issues and stakeholders are to be included in the decision analysis. The data were obtained from an experiment with 40 policy-makers, using a simulated case approach that focused on the complex biotechnology intellectual property system. They suggest that the use of such a DSS favours both the analysis of a greater range of perspectives and broader stakeholder participation, but does not strengthen either interdisciplinary integration or depth of stakeholder participation.",2017,21/11/2018 10:57,14/04/2020 08:34,,45-63,,1,26,,,,,,,,,,,,,,,,,,,,,1; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2MRDZ2FP,journalArticle,2017,"Liu, Ran; Yuan, Biao; Jiang, Zhibin",Mathematical model and exact algorithm for the home care worker scheduling and routing problem with lunch break requirements,INTERNATIONAL JOURNAL OF PRODUCTION RESEARCH,,0020-7543,10.1080/00207543.2016.1213917,,"Home health care or home care (HHC/HC) refers to the delivery of social, medical and paramedical services to clients in their own homes. Each day, care workers start from the HHC/HC centre, visit some clients and return to the centre. During the service delivery process, there is usually a lunch break for each worker. In this paper, we address a real-life home care worker scheduling and routing problem with the consideration of lunch break requirements. A three-index mathematical model is constructed for the problem. The problem is decomposed into a master problem and several pricing sub-problems, and is optimally solved by a branch-and-price (B&P) algorithm. Specifically, a sophisticated label-correcting algorithm is designed to address lunch break constraints in pricing sub-problems; some cutting-edge acceleration strategies are applied during the column generation process. Experimental results show that the proposed B&P algorithm is able to produce satisfied solutions within an acceptable runtime and outperforms the mixed integer programming solver CPLEX.",2017,21/11/2018 10:57,14/04/2020 08:34,,558-575,,2,55,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EVUGMEYN,journalArticle,2016,"Kortes-Miller, Katherine; Jones-Bonofiglio, Kristen; Hendrickson, Stephanie; Kelley, Mary Lou",Dying With Carolyn: Using Simulation to Improve Communication Skills of Unregulated Care Providers Working in Long-Term Care,JOURNAL OF APPLIED GERONTOLOGY,,0733-4648,10.1177/0733464815577139,,"This article examines the development, implementation, and evaluation of a pilot project utilizing high-fidelity simulation (HFS) to improve frontline staff members' confidence and skills to communicate about death and dying in long-term care homes. The target group was unregulated care providers who provide palliative care for residents and their families. Eighteen participants engaged in the educational intervention and evaluation. Results supported the effectiveness of HFS as an educational tool for unregulated health care providers. Quantitative data showed statistically significant improvements in participants' self-efficacy scores related to communicating about death and dying and end-of-life care. Qualitative data indicated that the experience was a valuable learning opportunity and helped participants develop insights into their own values, beliefs, and fears providing end-of-life care. HFS is therefore recommended as an innovative training strategy to improve palliative care communication in long-term care homes.",2016-12,21/11/2018 10:57,14/04/2020 08:34,,1259-1278,,12,35,,,,,,,,,,,,,,,,,,,,,"Humans; Program Evaluation; Female; Male; Middle Aged; Program Development; Pilot Projects; *Communication; Attitude of Health Personnel; *Long-Term Care; Patient Simulation; Death; 00; *palliative care; Self Efficacy; *education; *communication; *death and dying; *end of life; *High Fidelity Simulation Training; *high-fidelity simulation; *long-term care homes; *personal support workers; *unregulated care providers; Education, Nonprofessional/*methods; Nurses' Aides/*education/psychology; Palliative Care; Social Skills; Terminal Care; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8LFIYZZ7,journalArticle,2016,"McFadden, Pam; Crim, Andrew",Comparison of the Effectiveness of Interactive Didactic Lecture Versus Online Simulation-Based CME Programs Directed at Improving the Diagnostic Capabilities of Primary Care Practitioners,JOURNAL OF CONTINUING EDUCATION IN THE HEALTH PROFESSIONS,,0894-1912,10.1097/CEH.0000000000000061,,"Introduction:Diagnostic errors in primary care contribute to increased morbidity and mortality, and billions in costs each year. Improvements in the way practicing physicians are taught so as to optimally perform differential diagnosis can increase patient safety and lower the costs of care. This study represents a comparison of the effectiveness of two approaches to CME training directed at improving the primary care practitioner's diagnostic capabilities against seven common and important causes of joint pain.Methods:Using a convenience sampling methodology, one group of primary care practitioners was trained by a traditional live, expert-led, multimedia-based training activity supplemented with interactive practice opportunities and feedback (control group). The second group was trained online with a multimedia-based training activity supplemented with interactive practice opportunities and feedback delivered by an artificial intelligence-driven simulation/tutor (treatment group).Results:Before their respective instructional intervention, there were no significant differences in the diagnostic performance of the two groups against a battery of case vignettes presenting with joint pain. Using the same battery of case vignettes to assess postintervention diagnostic performance, there was a slight but not statistically significant improvement in the control group's diagnostic accuracy (P = .13). The treatment group, however, demonstrated a significant improvement in accuracy (P < .02; Cohen d, effect size = 0.79).Discussion:These data indicate that within the context of a CME activity, a significant improvement in diagnostic accuracy can be achieved by the use of a web-delivered, multimedia-based instructional activity supplemented by practice opportunities and feedback delivered by an artificial intelligence-driven simulation/tutor.",2016,21/11/2018 10:57,14/04/2020 08:34,,32-37,,1,36,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XJQYGSP4,journalArticle,2016,"Cooper, Simon J.; Kinsman, Leigh; Chung, Catherine; Cant, Robyn; Boyle, Jayne; Bull, Loretta; Cameron, Amanda; Connell, Cliff; Kim, Jeong-Ah; McInnes, Denise; McKay, Angela; Nankervis, Katrina; Penz, Erika; Rotter, Thomas",The impact of web-based and face-to-face simulation on patient deterioration and patient safety: protocol for a multi-site multi-method design,BMC HEALTH SERVICES RESEARCH,,1472-6963,10.1186/s12913-016-1683-0,,"Background: There are international concerns in relation to the management of patient deterioration which has led to a body of evidence known as the `failure to rescue' literature. Nursing staff are known to miss cues of deterioration and often fail to call for assistance. Medical Emergency Teams (Rapid Response Teams) do improve the management of acutely deteriorating patients, but first responders need the requisite skills to impact on patient safety. Methods/design: In this study we aim to address these issues in a mixed methods interventional trial with the objective of measuring and comparing the cost and clinical impact of face-to-face and web-based simulation programs on the management of patient deterioration and related patient outcomes. The education programs, known as `FIRST2ACT', have been found to have an impact on education and will be tested in four hospitals in the State of Victoria, Australia. Nursing staff will be trained in primary (the first 8 min) responses to emergencies in two medical wards using a face-to-face approach and in two medical wards using a web-based version FIRST2ACTWeb. The impact of these interventions will be determined through quantitative and qualitative approaches, cost analyses and patient notes review (time series analyses) to measure quality of care and patient outcomes. Discussion: In this 18 month study it is hypothesised that both simulation programs will improve the detection and management of deteriorating patients but that the web-based program will have lower total costs. The study will also add to our overall understanding of the utility of simulation approaches in the preparation of nurses working in hospital wards. (ACTRN12616000468426, retrospectively registered 8.4.2016).",07/09/2016,21/11/2018 10:57,14/04/2020 08:34,,,,,16,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XSG9G63C,journalArticle,2016,"Parakh, Anushri; Kortesniemi, Mika; Schindera, Sebastian T.",CT Radiation Dose Management: A Comprehensive Optimization Process for Improving Patient Safety,RADIOLOGY,,0033-8419,10.1148/radiol.2016151173,,"Rising concerns of radiation exposure from computed tomography have caused various advances in dose reduction technologies. While proper justification and optimization of scans has been the main focus to address increasing doses, the value of dose management has been largely overlooked. The purpose of this article is to explain the importance of dose management, provide an overview of the available options for dose tracking, and discuss the importance of a dedicated dose team. The authors also describe how a digital radiation tracking software can be used for analyzing the big data on doses for auditing patient safety, scanner utilization, and productivity, all of which have enormous personal and institutional implications. (C) RSNA, 2016",2016-09,21/11/2018 10:57,14/04/2020 08:35,,663-673,,3,280,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 58BMFSIM,journalArticle,2016,"Willan, Andrew R.",Accounting for treatment by center interaction in sample size determinations and the use of surrogate outcomes in the pessary for the prevention of preterm birth trial: a simulation study,TRIALS,,1745-6215,10.1186/s13063-016-1433-y,,"Background: The Pessary for the Prevention of Preterm Birth Study (PS3) is an international, multicenter, randomized clinical trial designed to examine the effectiveness of the Arabin pessary in preventing preterm birth in pregnant women with a short cervix. During the design of the study two methodological issues regarding power and sample size were raised. Since treatment in the Standard Arm will vary between centers, it is anticipated that so too will the probability of preterm birth in that arm. This will likely result in a treatment by center interaction, and the issue of how this will affect the sample size requirements was raised. The sample size requirements to examine the effect of the pessary on the baby's clinical outcome was prohibitively high, so the second issue is how best to examine the effect on clinical outcome. The approaches taken to address these issues are presented. Results: Simulation and sensitivity analysis were used to address the sample size issue. The probability of preterm birth in the Standard Arm was assumed to vary between centers following a Beta distribution with a mean of 0.3 and a coefficient of variation of 0.3. To address the second issue a Bayesian decision model is proposed that combines the information regarding the between-treatment difference in the probability of preterm birth from PS3 with the data from the Multiple Courses of Antenatal Corticosteroids for Preterm Birth Study that relate preterm birth and perinatal mortality/morbidity. The approach provides a between-treatment comparison with respect to the probability of a bad clinical outcome. The performance of the approach was assessed using simulation and sensitivity analysis. Accounting for a possible treatment by center interaction increased the sample size from 540 to 700 patients per arm for the base case. The sample size requirements increase with the coefficient of variation and decrease with the number of centers. Under the same assumptions used for determining the sample size requirements, the simulated mean probability that pessary reduces the risk of perinatal mortality/morbidity is 0.98. The simulated mean decreased with coefficient of variation and increased with the number of clinical sites. Conclusion: Employing simulation and sensitivity analysis is a useful approach for determining sample size requirements while accounting for the additional uncertainty due to a treatment by center interaction. Using a surrogate outcome in conjunction with a Bayesian decision model is an efficient way to compare important clinical outcomes in a randomized clinical trial in situations where the direct approach requires a prohibitively high sample size.",05/07/2016,21/11/2018 10:57,14/04/2020 08:35,,,,,17,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, S5T8B26N,journalArticle,2016,"Kobayashi, Susumu S.; Vali, Shireen; Kumar, Ansu; Singh, Neeraj; Abbasi, Taher; Sayeski, Peter P.",Identification of myeloproliferative neoplasm drug agents via predictive simulation modeling: assessing responsiveness with micro-environment derived cytokines,ONCOTARGET,,1949-2553,10.18632/oncotarget.8540,,"Previous studies have shown that the bone marrow micro-environment supports the myeloproliferative neoplasms (MPN) phenotype including via the production of cytokines that can induce resistance to frontline MPN therapies. However, the mechanisms by which this occurs are poorly understood. Moreover, the ability to rapidly identify drug agents that can act as adjuvants to existing MPN frontline therapies is virtually non-existent. Here, using a novel predictive simulation approach, we sought to determine the effect of various drug agents on MPN cell lines, both with and without the micro-environment derived inflammatory cytokines. We first created individual simulation models for two representative MPN cell lines; HEL and SET-2, based on their genomic mutation and copy number variation (CNV) data. Running computational simulations on these virtual cell line models, we identified a synergistic effect of two drug agents on cell proliferation and viability; namely, the Jak2 kinase inhibitor, G6, and the Bcl-2 inhibitor, ABT737. IL-6 did not show any impact on the cells due to the predicted lack of IL-6 signaling within these cells. Interestingly, TNF alpha increased the sensitivity of the single drug agents and their use in combination while IFN gamma decreased the sensitivity. In summary, this study predictively identified two drug agents that reduce MPN cell viability via independent mechanisms that was prospectively validated. Moreover, their efficacy is either potentiated or inhibited, by some of the micro-environment derived cytokines. Lastly, this study has validated the use of this simulation based technology to prospectively determine such responses.",14/06/2016,21/11/2018 10:57,14/04/2020 08:34,,35989-36001,,24,7,,,,,,,,,,,,,,,,,,,,,100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2UJGS3DW,journalArticle,2016,"Grigoras, Christos A.; Zervou, Fainareti N.; Zacharioudakis, Ioannis M.; Siettos, Constantinos I.; Mylonakis, Eleftherios",Isolation of C. difficile Carriers Alone and as Part of a Bundle Approach for the Prevention of Clostridium difficile Infection (CDI): A Mathematical Model Based on Clinical Study Data,PLOS ONE,,1932-6203,10.1371/journal.pone.0156577,,"Clostridium difficile infection is the most common hospital-acquired infection. Besides infected patients, carriers have emerged as a key player in C. difficile epidemiology. In this study, we evaluated the impact of identifying and isolating carriers upon hospital admission on the incidence of CDI incidence and hospital-acquired C. difficile colonization, as a single policy and as part of bundle approaches. We simulated C. difficile transmission using a stochastic mathematical approach, considering the contribution of carriers based on published literature. In the baseline scenario, CDI incidence was 6.18/1,000 admissions (95% CI, 5.72-6.65), simulating reported estimates from U.S. hospital discharges. The acquisition rate of C. difficile carriage was 9.72/1,000 admissions (95% CI, 9.15-10.31). Screening and isolation of colonized patients on admission to the hospital decreased CDI incidence to 4.99/1,000 admissions (95% CI, 4.59-5.42; relative reduction (RR) = 19.1%) and led to 36.2% reduction in the rate of hospital-acquired colonization. Simulating an antimicrobial stewardship program reduced CDI rate to 2.35/1,000 admissions (95% CI, 2.07-2.65). In sensitivity analysis, CDI incidence was less than 2.32/1,000 admissions (RR = 62.4%) in 95% of 1,000 simulations. The combined bundle, focusing on reducing C. difficile transmission from colonized patients and the individual risk of these patients to develop CDI, decreased significantly the incidence of both CDI and hospital-acquired colonization. Implementation of this bundle to current practice is expected to have an important impact in containing CDI.",03/06/2016,21/11/2018 10:57,14/04/2020 08:34,,,,6,11,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VPNKDVDP,journalArticle,2016,"Bowie, Paul; McNaughton, Elaine; Bruce, David; Holly, Deirdre; Forrest, Eleanor; Macleod, Marion; Kennedy, Susan; Power, Ailsa; Toppin, Denis; Black, Irene; Pooley, Janet; Taylor, Audrey; Swanson, Vivien; Kelly, Moya; Ferguson, Julie; Stirling, Suzanne; Wakeling, Judy; Inglis, Angela; Mckay, John; Sargeant, Joan",Enhancing the Effectiveness of Significant Event Analysis: Exploring Personal Impact and Applying Systems Thinking in Primary Care,JOURNAL OF CONTINUING EDUCATION IN THE HEALTH PROFESSIONS,,0894-1912,10.1097/CEH.0000000000000098,,"Introduction: Significant event analysis (SEA) is well established in many primary care settings but can be poorly implemented. Reasons include the emotional impact on clinicians and limited knowledge of systems thinking in establishing why events happen and formulating improvements. To enhance SEA effectiveness, we developed and tested “guiding tools” based on human factors principles. Methods: Mixed-methods development of guiding tools (Personal Booklet-to help with emotional demands and apply a human factors analysis at the individual level; Desk Pad-to guide a team-based systems analysis; and a written Report Format) by a multiprofessional “expert” group and testing with Scottish primary care practitioners who submitted completed enhanced SEA reports. Evaluation data were collected through questionnaire, telephone interviews, and thematic analysis of SEA reports. Results: Overall, 149/240 care practitioners tested the guiding tools and submitted completed SEA reports (62.1%). Reported understanding of how to undertake SEA improved postintervention (P<.001), while most agreed that the Personal Booklet was practical (88/123, 71.5%) and relevant to dealing with related emotions (93/123, 75.6%). The Desk Pad tool helped focus the SEA on systems issues (85/123, 69.1%), while most found the Report Format clear (94/123, 76.4%) and would recommend it (88/123, 71.5%). Most SEA reports adopted a systems approach to analyses (125/149, 83.9%), care improvement (74/149, 49.7), or planned actions (42/149, 28.2%). Discussion: Applying human factors principles to SEA potentially enables care teams to gain a systems-based understanding of why things go wrong, which may help with related emotional demands and with more effective learning and improvement.",2016,21/11/2018 10:57,14/04/2020 08:34,,195-205,,3,36,,,,,,,,,,,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, S7P4EH89,journalArticle,2016,"Oh, Chongsun; Novotny, April M.; Carter, Pamela L.; Ready, Ray K.; Campbell, Diane D.; Leckie, Maureen C.",Use of a simulation-based decision support tool to improve emergency department throughput,OPERATIONS RESEARCH FOR HEALTH CARE,,2211-6923,10.1016/j.orhc.2016.03.002,,"A simulation based decision support model was used in the redesign of an emergency department (ED) with close to 180,000 visits per year. In order to accommodate high patient volumes at a single site ED, improving patient throughput time is necessary to maintain operational efficiency and to provide high quality patient care. A throughput time goal of arrival to departure under 3 h for 80% of ED patients was selected as the redesign project objective. Using discrete event simulation modeling, target areas for improvement are identified including optimized process flow, resource allocation and operational policies. Simulation modeling allows ED leadership to make decisions on operational changes using quantitative information of the impact of what-if scenarios on key performance measures. Based on simulation data results, changes in ED processes were implemented that resulted in 81% of patients having a length of stay in the ED of less than 3 h; a 30% improvement in average patient length of stay. (C) 2016 Elsevier Ltd. All rights reserved.",2016-06,21/11/2018 10:57,14/04/2020 08:34,,29-39,,,9,,,,,,,,,,,,,,,,,,,,,00; Review,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EWK2VLNJ,journalArticle,2016,"Redjem, Rabeh; Marcon, Eric",Operations management in the home care services: a heuristic for the caregivers' routing problem,FLEXIBLE SERVICES AND MANUFACTURING JOURNAL,,1936-6582,10.1007/s10696-015-9220-8,,"Home Care Services (HCS) aim at providing complex coordinated health care for patients at their homes. This paper addresses the challenges of routing and scheduling HCS caregivers under precedence and coordination constraints, with patients receiving multiple caregivers. Moreover, the visits are performed simultaneously and possibly in a predefined order. The routing problem involves a fleet of vehicles to serve a number of customers at different locations. The objective is to find the minimal round for vehicle, while satisfying all the customers and without violating customers' time windows. It has been proved that the complexity of the caregivers routing problem is linked to both (1) the number of care activities per caregiver ratio and (2) the temporal dependencies rate. Given the poor performance of the mathematical modeling based on exact approaches, a heuristic approach called the Caregivers Routing Heuristic (CRH) has been developed and tested using real size instances. In fact, the exact approaches are not able to solve real size instances. The performance of the CRH has been evaluated using real size instances. The numerical results show that the CRH is very efficient in terms of computation times. Otherwise, the CRH is less sensitive than the exact approaches to both complexity axes: the temporal dependencies constraints and the ratio of the number of care activities per caregiver.",2016-06,21/11/2018 10:57,14/04/2020 08:35,,280-303,,"1-2, SI",28,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XD3DEAAP,journalArticle,2016,"Kang, Kyung-Ah; Kim, Shin-Jeong; Oh, Jina; Kim, Sunghee; Lee, Myung-Nam",Effectiveness of simulation with team-based learning in newborn nursing care,NURSING & HEALTH SCIENCES,,1441-0745,10.1111/nhs.12245,,"This study determines the effect of simulation with team-based learning (TBL) on newborn nursing care. This randomized controlled trial included 74 nursing students from one university located in Seoul, South Korea. Participants were categorized into two groups according to educational modality: one group involved both simulation and TBL, and the other involved simulation alone. Learning attitudes, academic achievement, and simulation performance were examined to assess effectiveness. The mean difference in learning attitudes between the two groups was non-significant. Low academic achievement differed significantly between the two groups (t=3.445, P=0.002). There was no significant difference in mean scores for simulation performance between the two groups. In this study, simulation with TBL was effective in improving learning outcomes. In current nursing education, various learning methods are employed within complex nursing situations and require flexibility and problem-solving approaches.",2016-06,21/11/2018 10:57,14/04/2020 08:34,,262-269,,2,18,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WUY6KADR,journalArticle,2016,"Wares, Joanna R.; Lawson, Barry; Shemin, Douglas; D'Agata, Erika M. C.",Evaluating Infection Prevention Strategies in Out-Patient Dialysis Units Using Agent-Based Modeling,PLOS ONE,,1932-6203,10.1371/journal.pone.0153820,,"Patients receiving chronic hemodialysis (CHD) are among the most vulnerable to infections caused by multidrug-resistant organisms (MDRO), which are associated with high rates of morbidity and mortality. Current guidelines to reduce transmission of MDRO in the outpatient dialysis unit are targeted at patients considered to be high-risk for transmitting these organisms: those with infected skin wounds not contained by a dressing, or those with fecal incontinence or uncontrolled diarrhea. Here, we hypothesize that targeting patients receiving antimicrobial treatment would more effectively reduce transmission and acquisition of MDRO. We also hypothesize that environmental contamination plays a role in the dissemination of MDRO in the dialysis unit. To address our hypotheses, we built an agent-based model to simulate different treatment strategies in a dialysis unit. Our results suggest that reducing antimicrobial treatment, either by reducing the number of patients receiving treatment or by reducing the duration of the treatment, markedly reduces overall colonization rates and also the levels of environmental contamination in the dialysis unit. Our results also suggest that improving the environmental decontamination efficacy between patient dialysis treatments is an effective method for reducing colonization and contamination rates. These findings have important implications for the development and implementation of future infection prevention strategies.",19/05/2016,21/11/2018 10:57,14/04/2020 08:34,,,,5,11,,,,,,,,,,,,,,,,,,,,,1; Agent Based; 310,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FG4B76RT,journalArticle,2016,"Liu, Shiyong; Osgood, Nathaniel; Gao, Qi; Xue, Hong; Wang, Youfa",Systems simulation model for assessing the sustainability and synergistic impacts of sugar-sweetened beverages tax and revenue recycling on childhood obesity prevention,JOURNAL OF THE OPERATIONAL RESEARCH SOCIETY,,0160-5682,10.1057/jors.2015.99,,"Recent years have witnessed prominent calls to tax sugar-sweetened beverages (SSB) to prevent obesity in the United States. Despite efforts to evaluate this proposed policy, limited data and no framework exist for evaluating long-term, dynamic, cumulative health impacts of taxing SSBs while recycling revenue to support related interventions. Systems simulation models offer an important new lens for evaluating policy interventions, but such models have traditionally under-conceptualized key implementation science concerns, such as sustainability, revenue recycling, and bringing interventions to scale. Using a system dynamics model representing implementation dynamics, this study contributes a simulation model to inform policymakers' understanding of how allocating revenue collected by SSB taxation across sustainable implementation strategies might maximize benefits of such taxation for childhood obesity prevention.",2016-05,21/11/2018 10:57,14/04/2020 08:34,,708-721,,5,67,,,,,,,,,,,,,,,,,,,,,System dynamics; 1; 220; system simulation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2MP354NG,journalArticle,2016,"Saoud, Manel Saad; Boubetra, Abdelhak; Attia, Safa",A Simulation Knowledge Extraction-based Decision Support System for the Healthcare Emergency Department,INTERNATIONAL JOURNAL OF HEALTHCARE INFORMATION SYSTEMS AND INFORMATICS,,1555-3396,10.4018/IJHISI.2016040102,,"Nowadays, healthcare systems services have become a serious concern for many countries across the world. Due to its complexity and Variability the Emergency Department (ED) is considered the most critical unit of the hospital and the healthcare systems in general. Increasing the patient satisfaction, reducing as much as possible the patient's waiting time and the patient's length of stay, and optimizing the resources utilization are the overriding preoccupation for any ED manager. To support the performance enhancement in the ED, simulation studies have profusely been involved. In this paper the authors describe a decision support system based on the combination of a simulation and a temporal knowledge extraction model for the operation improvement of the emergency department in the public hospital Lakhdar Bouzidi in Bordj Bou Arreridj (Algeria). Their methodology points out how agent-based modeling simulation can benefit from data mining analysis methods to provide a powerful decision support system that can help managers to improve the functioning of the ED.",2016-06,21/11/2018 10:57,14/04/2020 08:34,,19-37,,2,11,,,,,,,,,,,,,,,,,,,,,1; Agent Based; 320,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HADVREJ4,journalArticle,2016,"McElroy, Lisa M.; Schmidt, Kathryn A.; Richards, Christopher T.; McHugh, Megan C.; Holl, Jane L.; Adams, James G.; Ladner, Daniela P.",Reducing Hospital Readmissions via Optimization of Emergency Department Care,TRANSPLANTATION,,0041-1337,10.1097/TP.0000000000000988,,"Over the past 5 years, early hospital readmissions have become a national focus. With several recent publications highlighting the high rates of early hospital readmissions among transplant recipients, more work is needed to identify risk factors and strategies for reducing unnecessary readmissions among this patient population. Although the American Society of Transplant Surgeons is advocating the exclusion of transplant recipients from the calculation of hospital readmission rates, the outcome of their advocacy efforts remains uncertain. One potential strategy for reducing early hospital readmissions is to critically examine care received by transplant recipients in the emergency department (ED), a critical pathway to readmission. As a starting point, research is needed to assess rates of ED presentation among transplant recipients, diagnostic algorithms, and communication among clinical teams. Mixed-methods studies that enhance understanding of system-level barriers to optimized evaluation and treatment of transplant recipients in the ED may lead to quality improvement interventions that reduce unnecessary readmissions, even if the rates of transplant recipients presenting to the ED remains high.",2016-04,21/11/2018 10:57,14/04/2020 08:34,,886-888,,4,100,,,,,,,,,,,,,,,,,,,,,00; Review,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TEBBKLZJ,journalArticle,2016,"Ansah, John P.; Matchar, David B.; Malhotra, Rahul; Love, Sean R.; Liu, Chang; Do, Young",Projecting the effects of long-term care policy on the labor market participation of primary informal family caregivers of elderly with disability: insights from a dynamic simulation model,BMC GERIATRICS,,1471-2318,10.1186/s12877-016-0243-0,,"Background: Using Singapore as a case study, this paper aims to understand the effects of the current long-term care policy and various alternative policy options on the labor market participation of primary informal family caregivers of elderly with disability. Methods: A model of the long-term care system in Singapore was developed using System Dynamics methodology. Results: Under the current long-term care policy, by 2030, 6.9 percent of primary informal family caregivers (0.34 percent of the domestic labor supply) are expected to withdraw from the labor market. Alternative policy options reduce primary informal family caregiver labor market withdrawal; however, the number of workers required to scale up long-term care services is greater than the number of caregivers who can be expected to return to the labor market. Conclusions: Policymakers may face a dilemma between admitting more foreign workers to provide long-term care services and depending on primary informal family caregivers.",23/03/2016,21/11/2018 10:57,14/04/2020 08:34,,,,,16,,,,,,,,,,,,,,,,,,,,,00; Review,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, P8L95VNZ,journalArticle,2016,"Ernecoff, Natalie C.; Keane, Christopher R.; Albert, Steven M.",Health behavior change in advance care planning: an agent-based model,BMC PUBLIC HEALTH,,1471-2458,10.1186/s12889-016-2872-9,,"Background: A practical and ethical challenge in advance care planning research is controlling and intervening on human behavior. Additionally, observing dynamic changes in advance care planning (ACP) behavior proves difficult, though tracking changes over time is important for intervention development. Agent-based modeling (ABM) allows researchers to integrate complex behavioral data about advance care planning behaviors and thought processes into a controlled environment that is more easily alterable and observable. Literature to date has not addressed how best to motivate individuals, increase facilitators and reduce barriers associated with ACP. We aimed to build an ABM that applies the Transtheoretical Model of behavior change to ACP as a health behavior and accurately reflects: 1) the rates at which individuals complete the process, 2) how individuals respond to barriers, facilitators, and behavioral variables, and 3) the interactions between these variables. Methods: We developed a dynamic ABM of the ACP decision making process based on the stages of change posited by the Transtheoretical Model. We integrated barriers, facilitators, and other behavioral variables that agents encounter as they move through the process. Results: We successfully incorporated ACP barriers, facilitators, and other behavioral variables into our ABM, forming a plausible representation of ACP behavior and decision-making. The resulting distributions across the stages of change replicated those found in the literature, with approximately half of participants in the action-maintenance stage in both the model and the literature. Conclusions: Our ABM is a useful method for representing dynamic social and experiential influences on the ACP decision making process. This model suggests structural interventions, e.g. increasing access to ACP materials in primary care clinics, in addition to improved methods of data collection for behavioral studies, e.g. incorporating longitudinal data to capture behavioral dynamics.",29/02/2016,21/11/2018 10:57,14/04/2020 08:34,,,,,16,,,,,,,,,,,,,,,,,,,,,"Humans; *Health Behavior; *Decision Making; *Models, Psychological; 1; *Advance Care Planning; Agent Based; 320",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BLADLTMW,journalArticle,2016,"Helm, Jonathan E.; Alaeddini, Adel; Stauffer, Jon M.; Bretthauer, Kurt M.; Skolarus, Ted A.",Reducing Hospital Readmissions by Integrating Empirical Prediction with Resource Optimization,PRODUCTION AND OPERATIONS MANAGEMENT,,1059-1478,10.1111/poms.12377,,"Hospital readmissions present an increasingly important challenge for health-care organizations. Readmissions are expensive and often unnecessary, putting patients at risk and costing $15billion annually in the United States alone. Currently, 17% of Medicare patients are readmitted to a hospital within 30days of initial discharge with readmissions typically being more expensive than the original visit to the hospital. Recent legislation penalizes organizations with a high readmission rate. The medical literature conjectures that many readmissions can be avoided or mitigated by post-discharge monitoring. To develop a good monitoring plan it is critical to anticipate the timing of a potential readmission and to effectively monitor the patient for readmission causing conditions based on that knowledge. This research develops new methods to empirically generate an individualized estimate of the time to readmission density function and then uses this density to optimize a post-discharge monitoring schedule and staffing plan to support monitoring needs. Our approach integrates classical prediction models with machine learning and transfer learning to develop an empirical density that is personalized to each patient. We then transform an intractable monitoring plan optimization with stochastic discharges and health state evolution based on delay-time models into a weakly coupled network flow model with tractable subproblems after applying a new pruning method that leverages the problem structure. Using this multi-methodologic approach on two large inpatient datasets, we show that optimal readmission prediction and monitoring plans can identify and mitigate 40-70% of readmissions before they generate an emergency readmission.",2016-02,21/11/2018 10:57,14/04/2020 08:34,,233-257,,2,25,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 444SXM5R,journalArticle,2016,"Ha, Joon; Satin, Leslie S.; Sherman, Arthur S.","A Mathematical Model of the Pathogenesis, Prevention, and Reversal of Type 2 Diabetes",ENDOCRINOLOGY,,0013-7227,10.1210/en.2015-1564,,"Type 2 diabetes (T2D) is generally thought to result from the combination of 2 metabolic defects, insulin resistance, which increases the level of insulin required to maintain glucose within the normal range, and failure of insulin-secreting pancreatic beta-cells to compensate for the increased demand. We build on a mathematical model pioneered by Topp and colleagues to elucidate how compensation succeeds or fails. Their model added a layer of slow negative feedback to the classic insulin-glucose loop in the form of a slow, glucose-dependent birth and death law governing beta-cell mass. We add to that model regulation of 2 aspects of beta-cell function on intermediate time scales. The model quantifies the relative contributions of insulin action and insulin secretion defects to T2D and explains why prevention is easier than cure. The latter is a consequence of a threshold separating the normoglycemic and diabetic states (bistability), which also underlies the success of bariatric surgery and acute caloric restriction in rapidly reversing T2D. The threshold concept gives new insight into “Starling's Law of the Pancreas,” whereby insulin secretion is higher for prediabetics and early diabetics than for normal individuals.",2016-02,21/11/2018 10:57,14/04/2020 08:34,,624-635,,2,157,,,,,,,,,,,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VQVL5VJV,conferencePaper,2016,"Aitao, Zhou; Kai, Wang; Yuyu, Kong; Ang, Liu",Numerical simulation for propagation characteristics of outburst shock wave and gas flow when outburst prevention facilities fail,OPERATIONAL AND ENVIRONMENTAL MINE HEALTH AND SAFETY PRACTICE AND INNOVATION,978-1-77247-005-5,,,,"In order to numerically simulate the propagation characteristics of outburst shock waves and gas flow when outburst prevention facilities fail, the propagation characteristics model of outburst shock waves and gas flow was established, and the mechanism of gas counter current was analyzed. The propagation characteristics of shock wave and gas flow at two types of geometry models were numerically simulated by using Fluent software. The results show that most of the gas flow produced by outbursts propagates to intake airways when crossheading with an excavation roadway at the same level; however, when crossheading with an excavation roadway not at the same level, gas is mainly discharged from the return airway, and the effect of the gas flow on the intake airway is small. The results have important theoretical and practical significance for mine disaster rescue and preventing secondary accidents.",2016,21/11/2018 10:57,14/04/2020 08:34,,564-573,,,,,,,,,,,Henan Polytechn Univ; Univ Sci & Technol Beijing; China Univ Min & Technol,,,,,,,,,,"

3rd International Symposium on Mine Safety Science and Engineering (ISMS), McGill Univ, Montreal, CANADA, AUG 13-19, 2016

",,,00; 100,,"Mitri, H and Shnorhokian, S and Kumral, M and Sasmito, A and Sainoki, A",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, W5KLN6GK,journalArticle,2016,"Gomez, Andres; Carmen Carnero, Maria",Decision Support System for maintenance policy optimization in medicinal gases subsystems,IFAC PAPERSONLINE,,2405-8963,10.1016/j.ifacol.2016.11.046,,"This article shows an innovative decision support system built by integrating Markov chains with the multicriteria Measuring Attractiveness by a Categorical Based Evaluation Technique (MACBETH) for managing medical assets in a Health Care Organization. This model makes a choice of optimal maintenance policies on different typologies of subsystems for the distribution of medicinal gases and vacuum. The model uses a decision group made up of various departmental heads of a Health Care Organization. It should be noted that it has also been applied to a public general hospital. (C) 2016, IFAC (International Federation of Automatic Control) Hosting by Elsevier Ltd. All rights reserved.",2016,21/11/2018 10:58,14/04/2020 08:34,,268-273,,28,49,,,,,,,,,,,,,,,,,,"

3rd IFAC Workshop on Advanced Maintenance Engineering, Services and Technology (AMEST), Biarritz, FRANCE, OCT 19-21, 2016

",,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, S3D5WJWY,conferencePaper,2016,"Nikolaev, Rosen; Shabanova, Maria",APPLICATION OF COMPUTER TOOLS FOR PREVENTION OF MISTAKES IN A SOLUTION OF EXAM TASKS OF OPTIMIZATION INVESTMENT,"SGEM 2016, BK 1: PSYCHOLOGY AND PSYCHIATRY, SOCIOLOGY AND HEALTHCARE, EDUCATION CONFERENCE PROCEEDINGS, VOL I",978-619-7105-70-4,,,,"Background: A task of mathematical methods application to fmancial situations was included in the Unified State Exam for high school graduates in 2015. The economic sphere was not selected by accident: increase in the population's financial literacy level has state significance. This task was presented by some situations. The problem on investigation of the discrete function in financial situations was the most complex for students. They tried to apply discrete function methods to research of functions and made a lot of mistakes. Methods: The authors of this paper have analyzed all possible causes of errors and have constructed dynamic worksheets for their visualization. They used GeoGebra tools for this work. The authors applied these dynamic worksheets at their lectures where students and mathematics teachers were offered new tasks with a similar idea, and their solutions were evaluated. Results: The computer tools helped students and their teachers to understand the conditions and characteristics of applying discrete function methods to research of continuous functions and to solve quite difficult problems. Conclusions: Dynamic visualization supports students' imagination. It makes a mental experiment visible. This is the basis for infmitesimal methods which can be used in teaching.",2016,21/11/2018 10:58,14/04/2020 08:35,,549-556,,,,,,,International Multidisciplinary Scientific Conferences on Social Sciences and Arts,,,,Bulgarian Acad Sci; Acad Sci Czech Republ; Latvian Acad Sci; Polish Acad Sci; Russian Acad Sci; Serbian Acad Sci & Arts; Slovak Acad Sci; Natl Acad Sci Ukraine; Natl Acad Sci Armenia; Sci Council Japan; World Acad Sci; European Acad Sci Arts & Letters; Acad Fine Arts Zagreb Croatia; Croatian Acad Sci & Arts; Acad Sci Moldova; Montenegrin Acad Sci & Arts; Georgian Acad Sci; Acad Fine Arts & Design Bratislava; Russian Acad Arts; Turkish Acad Sci; Bulgarian Cultural Inst Vienna,,,,,,,,,,"

3rd International Multidisciplinary Scientific Conference on Social Sciences and Arts, SGEM 2016, Albena, BULGARIA, AUG 24-30, 2016

",,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GMXCYGR2,conferencePaper,2016,"Maroufkhani, Azadeh; Lanzarone, Ettore; Castelnovo, Cecily; Di Mascolo, Maria",A Discrete Event Simulation Model for the Admission of Patients to a Home Care Rehabilitation Service,HEALTH CARE SYSTEMS ENGINEERING FOR SCIENTISTS AND PRACTITIONERS,978-3-319-35132-2 978-3-319-35130-8,,10.1007/978-3-319-35132-2_9,,"An important rising of the Home Care (HC) sector has been observed in all of Western countries during the last years, due to demographic and epidemiological changes, and cost reduction constraints. Indeed, the demographic trend of recent years has been characterised by a significant life expectancy increase, resulting into both an increased demand and a higher care complexity due to the presenceof chronic degenerative diseases and co-morbidities. This is also combined witha social fragility phenomenon, i.e., families are fragmented and care services are often provided to sick and poor patients who live alone. Institutionalisation cannot be the solution, because of high costs and low quality of life for patients. In response, there are nowadays several types of HC providers, ranging from general providers to specialised ones that take care of the multidimensional needs of specificpatient classes. Eligible patients can choose the provider among the available ones accredited for the specific service required. The aim of our work is to provide a quantitative tool, based onDiscrete EventSimulation (DES), for analysing and optimising the admission process in HCservices. The choice of a simulation model rather than othertechniques, e.g.,queueing networks, is motivated by the high versatility we want for the tool,in particular in the choice of the probability density functions for the randomparameters (e.g., treatment duration and patient’s conditions) and in the finemodelling of the admission policies",2016,21/11/2018 10:58,14/04/2020 08:34,,91-100,,,169,,,,Springer Proceedings in Mathematics & Statistics,,,,,,,,,,,,,,"

2nd International Conference on Health Care Systems Engineering (HCSE), St Joseph St Luc Hosp, Lyon, FRANCE, MAY 27-29, 2015

",,,1; 310; Discrete Event,,"Matta, A and Sahin, E and Li, J and Guinet, A and Vandaele, NJ",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GTBRQ23D,conferencePaper,2016,"Zhong, Xiang; Lee, Hyo Kyung; Williams, Molly; Kraft, Sally; Sleeth, Jeffery; Welnick, Richard; Hoschild, Lori; Li, Jingshan",Staffing Ratio Analysis in Primary Care Redesign: A Simulation Approach,HEALTH CARE SYSTEMS ENGINEERING FOR SCIENTISTS AND PRACTITIONERS,978-3-319-35132-2 978-3-319-35130-8,,10.1007/978-3-319-35132-2_13,,"Primary care physicians are facing an enormous amount of tasks which make them at high risk of burnout. However, many functions they are performing do not require their professional training (Sinsky et al. 2010, 2013). To alleviate this situation, team-based care, in which support staff work collaboratively with patients and their caregivers to achieve coordinated and high-quality care, establishes a cornerstone of the modern primary care model (Patient Centered Primary Care Implementation Work Group; Doherty & Crowley 2013; Patel et al. 2013a). These redesigning efforts share a common direction: more emphasis on expanding and elevating the role of team members with lower level clinical credentials (Berra). Expanding staffing and shifting roles offers possible advantages. However, the question of what should be the right staffing ratio between support staff and physician is still unanswered. In recent years, such a question has been studied prevalently (Berra; Wharrad & Robinson 1999; OECD 2007; Reinhardt et al. 1972; Peikes et al. 2014; Patel et al. 2013b; Reid et al. 2010). Multiple ratios, such as 2.6:1 (Berra), 2:1 (Wharrad & Robinson 1999), 2.9–3.1:1 (OECD 2007), 4.25:1 (Patel et al. 2013b), have been proposed for various systems. Thus, the optimal staffing ratio is still unclear. This motivates our study to identify whether there is a fundamental rule governing optimal staffing ratio under various practice settings.",2016,21/11/2018 10:58,14/04/2020 08:35,,133-144,,,169,,,,Springer Proceedings in Mathematics & Statistics,,,,,,,,,,,,,,"

2nd International Conference on Health Care Systems Engineering (HCSE), St Joseph St Luc Hosp, Lyon, FRANCE, MAY 27-29, 2015

",,,00; 100,,"Matta, A and Sahin, E and Li, J and Guinet, A and Vandaele, NJ",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5LJ6NPRK,conferencePaper,2016,"Mellor, Nicholas; Horton, Hetty; Luke, David; Meadows, Jon; Chatterjee, Arunangsu; Gale, Thomas",Experience of using simulation technology and analytics during the Ebola crisis to empower frontline health workers and improve the integrity of public health systems,"HUMANITARIAN TECHNOLOGY: SCIENCE, SYSTEMS AND GLOBAL IMPACT 2016, HUMTECH2016",,,10.1016/j.proeng.2016.08.062,,"The Ebola outbreak highlighted the challenge of health security and particularly of how best to give frontline workers the knowledge, confidence and competence to respond effectively. The goal was to develop a tool to improve infection prevention and control through local capacity building within the context of an emergency response. The research showed that digital technology could be a powerful `force multiplier' allowing much greater access to high fidelity training during an outbreak and keeping it current as protocols evolved or new safety critical steps were identified. Tailoring training to the local context was crucial to its relevance and accessibility. This initiative used a novel approach to the development of the training tool - ebuddi. It used agile development to co-create the tool with active participation of local communities. A further pilot showed how it could be extended to meet the longer term needs of triage training and ensure better quality assurance. In the longer term it may have the potential to improve compliance with International Health Regulations, be adapted for future emergencies, and contribute to global health security. (C) 2016 The Authors. Published by Elsevier Ltd.",2016,21/11/2018 10:58,14/04/2020 08:34,,44-52,,,159,,,,Procedia Engineering,,,,,,,,,,,,,,"

Humanitarian Technology - Science, Systems and Global Impact (HumTech), Boston, MA, JUN 07-09, 2016

",,,00; 110,,"Vidan, A and Shoag, D",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VEB9W8GX,journalArticle,2016,"Girod, Sabine; Schvartzman, Sara C.; Gaudilliere, Dyani; Salisbury, Kenneth; Silva, Rebeka",Haptic feedback improves surgeons' user experience and fracture reduction in facial trauma simulation,JOURNAL OF REHABILITATION RESEARCH AND DEVELOPMENT,,0748-7711,10.1682/JRRD.2015.03.0043,,"Computer-assisted surgical (CAS) planning tools are available for craniofacial surgery but are usually based on computer-aided design (CAD) tools that lack the ability to detect the collision of virtual objects (i.e., fractured bone segments). We developed a CAS system featuring a sense of touch (haptic) that enables surgeons to physically interact with individual, patient-specific anatomy and immerse in a three-dimensional virtual environment. In this study, we evaluated initial user experience with our novel system compared to an existing CAD system. Ten surgery resident trainees received a brief verbal introduction to both the haptic and CAD systems. Users simulated mandibular fracture reduction in three clinical cases within a 15 min time limit for each system and completed a questionnaire to assess their subjective experience. We compared standard landmarks and linear and angular measurements between the simulated results and the actual surgical outcome and found that haptic simulation results were not significantly different from actual postoperative outcomes. In contrast, CAD results significantly differed from both the haptic simulation and actual postoperative results. In addition to enabling a more accurate fracture repair, the haptic system provided a better user experience than the CAD system in terms of intuitiveness and self-reported quality of repair.",2016,21/11/2018 10:58,14/04/2020 08:34,,561-569,,5,53,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6JDDHIKY,journalArticle,2016,"Qiu, Yunzhe; Song, Jie; Liu, Zekun",A simulation optimisation on the hierarchical health care delivery system patient flow based on multi-fidelity models,INTERNATIONAL JOURNAL OF PRODUCTION RESEARCH,,0020-7543,10.1080/00207543.2016.1197437,,"The mismatching patient flow distribution in the health care system in urban China is a great social issue that attracts lots of public attention. In this research, we propose a simulation-based optimisation method using the multi-fidelity optimisation with ordinal transformation (OT) and optimal sampling (OS) ((MOTOS)-T-2) algorithm to evaluate the patient flow distribution, so as to continuously improve the hierarchical health care service system. The low-fidelity model applying the queueing network theory is constructed for the OT part of the (MOTOS)-T-2, followed by a high-fidelity but time-consuming discrete event simulation model for the OS part. An empirical study on the background of the hierarchical health care delivery system in China is presented, where the proposed (MOTOS)-T-2 method is implemented to optimise the system profit by guiding the patient flow distribution. Acomparison with other widely used simulation optimisationmethods sustains the efficacy of the (MOTOS)-T-2 with the evidence that acquiring effective information from the low-fidelity model indeed retrenches the computing budget used to explore the feasible domain.",2016,21/11/2018 10:58,14/04/2020 08:35,,6478-6493,,"21, SI",54,,,,,,,,,,,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, G4FV2QMH,journalArticle,2016,"Yip, Kenneth; Pang, Suk-King; Chan, Kui-Tim; Chan, Chi-Kuen; Lee, Tsz-Leung",Improving outpatient phlebotomy service efficiency and patient experience using discrete-event simulation,INTERNATIONAL JOURNAL OF HEALTH CARE QUALITY ASSURANCE,,0952-6862,10.1108/IJHCQA-08-2015-0093,,"Purpose - The purpose of this paper is to present a simulation modeling application to reconfigure the outpatient phlebotomy service of an acute regional and teaching hospital in Hong Kong, with an aim to improve service efficiency, shorten patient queuing time and enhance workforce utilization. Design/methodology/approach - The system was modeled as an inhomogeneous Poisson process and a discrete-event simulation model was developed to simulate the current setting, and to evaluate how various performance metrics would change if switched from a decentralized to a centralized model. Variations were then made to the model to test different workforce arrangements for the centralized service, so that managers could decide on the service's final configuration via an evidence-based and data-driven approach. Findings - This paper provides empirical insights about the relationship between staffing arrangement and system performance via a detailed scenario analysis. One particular staffing scenario was chosen by manages as it was considered to strike the best balance between performance and workforce scheduled. The resulting centralized phlebotomy service was successfully commissioned. Practical implications - This paper demonstrates how analytics could be used for operational planning at the hospital level. The authors show that a transparent and evidence-based scenario analysis, made available through analytics and simulation, greatly facilitates management and clinical stakeholders to arrive at the ideal service configuration. Originality/value - The authors provide a robust method in evaluating the relationship between workforce investment, queuing reduction and workforce utilization, which is crucial for managers when deciding the delivery model for any outpatient-related service.",2016,21/11/2018 10:58,14/04/2020 08:35,,733-743,,7,29,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ZIN6ZB6X,journalArticle,2016,"Collins, Linda M.; Kugler, Kari C.; Gwadz, Marya Viorst",Optimization of Multicomponent Behavioral and Biobehavioral Interventions for the Prevention and Treatment of HIV/AIDS,AIDS AND BEHAVIOR,,1090-7165,10.1007/s10461-015-1145-4,,"To move society toward an AIDS-free generation, behavioral interventions for prevention and treatment of HIV/AIDS must be not only effective, but also cost-effective, efficient, and readily scalable. The purpose of this article is to introduce to the HIV/AIDS research community the multiphase optimization strategy (MOST), a new methodological framework inspired by engineering principles and designed to develop behavioral interventions that have these important characteristics. Many behavioral interventions comprise multiple components. In MOST, randomized experimentation is conducted to assess the individual performance of each intervention component, and whether its presence/absence/setting has an impact on the performance of other components. This information is used to engineer an intervention that meets a specific optimization criterion, defined a priori in terms of effectiveness, cost, cost-effectiveness, and/or scalability. MOST will enable intervention science to develop a coherent knowledge base about what works and does not work. Ultimately this will improve behavioral interventions systematically and incrementally.",2016-01,21/11/2018 10:58,14/04/2020 08:34,,S197-S214,,1,20,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MXWG396M,journalArticle,2016,"Luisa Nicieza-Garcia, Maria; Esther Salgueiro-Vazquez, Maria; Jose Jimeno-Demuth, Francisco; Manso, Gloria",Optimization of information on the medication of polypharmacy patients in primary care,GACETA SANITARIA,,0213-9111,10.1016/j.gaceta.2015.10.009,,"As part of the protocol of the Health Service of the Principality of Asturias (Spain), primary care physicians periodically receive listings of the treatments of patients of any age taking 10 or more drugs/day for 6 months. Currently, the Health Service of the Principality of Asturias is developing a project that aims to assess the medications of polypharmacy patients. The aim is to identify: 1) the consumption of medicines of low therapeutic usefulness, 2) the consumption of potentially nephrotoxic drugs in patients with a low glomerular filtration rate, and 3) potentially inappropriate prescribing in patients aged 65 years or older. The project was started in Health Area II and the aim is to extend it to the remaining health areas. In our opinion, its automation and general implementation could be useful to optimize drug prescription. (C) 2015 SESPAS. Published by Elsevier Espana, S.L.U.",2016-02,21/11/2018 10:58,14/04/2020 08:34,,69-72,,1,30,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6S4RIHPH,journalArticle,2016,"Cao, Qi; Buskens, Erik; Feenstra, Talitha; Jaarsma, Tiny; Hillege, Hans; Postmus, Douwe",Continuous-Time Semi-Markov Models in Health Economic Decision Making: An Illustrative Example in Heart Failure Disease Management,MEDICAL DECISION MAKING,,0272-989X,10.1177/0272989X15593080,,"Continuous-time state transition models may end up having large unwieldy structures when trying to represent all relevant stages of clinical disease processes by means of a standard Markov model. In such situations, a more parsimonious, and therefore easier-to-grasp, model of a patient's disease progression can often be obtained by assuming that the future state transitions do not depend only on the present state (Markov assumption) but also on the past through time since entry in the present state. Despite that these so-called semi-Markov models are still relatively straightforward to specify and implement, they are not yet routinely applied in health economic evaluation to assess the cost-effectiveness of alternative interventions. To facilitate a better understanding of this type of model among applied health economic analysts, the first part of this article provides a detailed discussion of what the semi-Markov model entails and how such models can be specified in an intuitive way by adopting an approach called vertical modeling. In the second part of the article, we use this approach to construct a semi-Markov model for assessing the long-term cost-effectiveness of 3 disease management programs for heart failure. Compared with a standard Markov model with the same disease states, our proposed semi-Markov model fitted the observed data much better. When subsequently extrapolating beyond the clinical trial period, these relatively large differences in goodness-of-fit translated into almost a doubling in mean total cost and a 60-d decrease in mean survival time when using the Markov model instead of the semi-Markov model. For the disease process considered in our case study, the semi-Markov model thus provided a sensible balance between model parsimoniousness and computational complexity.",2016-01,21/11/2018 10:58,14/04/2020 08:34,,59-71,,1,36,,,,,,,,,,,,,,,,,,,,,"Humans; *Markov Chains; Models, Theoretical; *Disease Management; Disease Progression; Cost-Benefit Analysis/*methods; *Decision Making; 1; *continuous-time semi-Markov model; *heart failure disease management; *vertical modeling; Heart Failure/*economics/*therapy; Markov; 320",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CNEPCVHV,journalArticle,2016,"Zhang, Fengli; Johnson, Dana; Johnson, Mark; Watkins, David; Froese, Robert; Wang, Jinjiang",Decision support system integrating GIS with simulation and optimisation for a biofuel supply chain,RENEWABLE ENERGY,,0960-1481,10.1016/j.renene.2015.07.041,,"A range of economic and societal issues has resulted from fossil fuel consumption in the transportation sector in the U.S. These include health related air pollution, climate change, dependence on imported oil, and other oil related national security concerns. Biofuels production from various lignocellulosic biomass types, such as wood, forest residues, and agriculture residues, have the potential to replace a portion of the total fossil fuel consumption. This study focused on locating biofuel facilities and designing the biofuel supply chain to minimise the overall cost. For this purpose, an integrated methodology was proposed by combining the Geographic Information System technology with simulation and optimisation modelling methods. The GIS-based method was used as a precursor for selecting biofuel facility locations by employing a series of decision factors. The identified candidate sites for biofuel production served as inputs for simulation and optimisation modelling. The simulation/optimisation model and identified locations provided an integrated decision support system for decision makers to determine the optimal cost, energy consumption, and emissions for candidate locations. This novel methodology development extends prior research. (C) 2015 Elsevier Ltd. All rights reserved.",2016-01,21/11/2018 10:58,14/04/2020 08:35,,740-748,,,85,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IRCRLZKJ,journalArticle,2015,"Demir, Eren; Vasilakis, Christos; Lebcir, Reda; Southern, David",A simulation-based decision support tool for informing the management of patients with Parkinson's disease,INTERNATIONAL JOURNAL OF PRODUCTION RESEARCH,,0020-7543,10.1080/00207543.2015.1029647,,"We describe a decision support toolkit that was developed with the aim of assisting those responsible with the management and treatment of Parkinson's disease (PD) in the UK. Having created a baseline model and established its face validity, the toolkit captures the complexity of PD services at a sufficient level and operates within a user-friendly environment; that is, an interface was built to allow users to specify their own local PD service and input their own estimates or data of service demands and capacities. The main strength of this decision support tool is the adoption of a team approach to studying the system, involving six PD specialist nurses across the country, ensuring that variety of views and suggestions are taken as well as systems modelling and simulations. The tool enables key decision-makers to estimate the likely impact of changes, such as increased use of community services on activity, cost, staffing levels, skill-mix and utilisation of resources. Such previously unobtainable quantitative information can be used to support business cases for changes in the increased use of community services and its impact on clinical outcomes (disease progression), nurse visits and costing.",17/12/2015,21/11/2018 10:58,14/04/2020 08:34,,7238-7251,,"24, SI",53,,,,,,,,,,,,,,,,,,,,,1; 320,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8QWK5CVD,journalArticle,2015,"Fleischmann, Anselm",Calibrating intensities for long-term care multiple-state Markov insurance model,EUROPEAN ACTUARIAL JOURNAL,,2190-9733,10.1007/s13385-015-0117-4,,"Multiple-state Markov models for life or health insurance have been studied for a considerable amount of time (Christiansen, in Multiple-state models in health insurance, 2012; Helwich, in Durational effects and non-smooth semi-Markov models in life insurance, 2008; Koller, in Stochastische Modelle in der Lebensversicherung, 2000). Given the ease and straight forward way of modelling complex tariffs within the modelling framework of multiple-state Markov models it is surprising to observe that these models still await wide-spread use. Having introduced tariffs for private, supplementary long-term care insurance in the Austrian private health insurance market, the biggest obstacle for using a multiple-state Markov model has been its calibration of the underlying state-change intensities to empirical data. These difficulties were addressed by developing and applying a method to extract state-change intensities from published empirical observations of prevalence rates under assumptions that were deemed sufficient for a portfolio of contracts providing recurring payments dependent on degree of severity of long-term care need. The method developed is described in detail, the used empirical data and derived results are given. This paper is intended to foster further discussion and research regarding calibration methods for advanced insurance models.",2015-12,21/11/2018 10:58,14/04/2020 08:34,,327-354,,2,5,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ZIN5SKR8,journalArticle,2015,"van der Heijden, A. A. W. A.; Feenstra, T. L.; Hoogenveen, R. T.; Niessen, L. W.; de Bruijne, M. C.; Dekker, J. M.; Baan, C. A.; Nijpels, G.",Policy evaluation in diabetes prevention and treatment using a population-based macro simulation model: the MICADO model,DIABETIC MEDICINE,,0742-3071,10.1111/dme.12811,,"Aims To test a simulation model, the MICADO model, for estimating the long-term effects of interventions in people with and without diabetes. Methods The MICADO model includes micro-and macrovascular diseases in relation to their risk factors. The strengths of this model are its population scope and the possibility to assess parameter uncertainty using probabilistic sensitivity analyses. Outcomes include incidence and prevalence of complications, quality of life, costs and cost-effectiveness. We externally validated MICADO's estimates of micro-and macrovascular complications in a Dutch cohort with diabetes (n = 498 400) by comparing these estimates with national and international empirical data. Results For the annual number of people undergoing amputations, MICADO's estimate was 592 (95% interquantile range 291-842), which compared well with the registered number of people with diabetes-related amputations in the Netherlands (728). The incidence of end-stage renal disease estimated using the MICADO model was 247 people (95% interquartile range 120-363), which was also similar to the registered incidence in the Netherlands (277 people). MICADO performed well in the validation of macrovascular outcomes of population-based cohorts, while it had more difficulty in reflecting a highly selected trial population. Conclusions Validation by comparison with independent empirical data showed that the MICADO model simulates the natural course of diabetes and its micro-and macrovascular complications well. As a population-based model, MICADO can be applied for projections as well as scenario analyses to evaluate the long-term (cost-) effectiveness of population-level interventions targeting diabetes and its complications in the Netherlands or similar countries.",2015-12,21/11/2018 10:58,14/04/2020 08:34,,1580-1587,,12,32,,,,,,,,,,,,,,,,,,,,,1; Markov; 220,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LV56KPRN,journalArticle,2015,"Zheng, Bichen; Zhang, Jinghe; Yoon, Sang Won; Lam, Sarah S.; Khasawneh, Mohammad; Poranki, Srikanth",Predictive modeling of hospital readmissions using metaheuristics and data mining,EXPERT SYSTEMS WITH APPLICATIONS,,0957-4174,10.1016/j.eswa.2015.04.066,,"This research studies the risk prediction of hospital readmissions using metaheuristic and data mining approaches. This is a critical issue in the U.S. healthcare system because a large percentage of preventable hospital readmissions derive from a low quality of care during patients' stays in the hospital as well as poor arrangement of the discharge process. To reduce the number of hospital readmissions, the Centers for Medicare and Medicaid Services has launched a readmission penalty program in which hospitals receive reduced reimbursement for high readmission rates for Medicare beneficiaries. In the current practice, patient readmission risk is widely assessed by evaluating a LACE score including length of stay (L), acuity level of admission (A), comorbidity condition (C), and use of emergency rooms (E). However, the LACE threshold classifying high- and low-risk readmitted patients is set up by clinic practitioners based on specific circumstances and experiences. This research proposed various data mining approaches to identify the risk group of a particular patient, including neural network model, random forest (RF) algorithm, and the hybrid model of swarm intelligence heuristic and support vector machine (SVM). The proposed neural network algorithm, the RF and the SVM classifiers are used to model patients' characteristics, such as their ages, insurance payers, medication risks, etc. Experiments are conducted to compare the performance of the proposed models with previous research. Experimental results indicate that the proposed prediction SVM model with particle swarm parameter tuning outperforms other algorithms and achieves 78.4% on overall prediction accuracy, 97.3% on sensitivity. The high sensitivity shows its strength in correctly identifying readmitted patients. The outcome of this research will help reduce overall hospital readmission rates and allow hospitals to utilize their resources more efficiently to enhance interventions for high-risk patients. (C) 2015 Elsevier Ltd. All rights reserved.",15/11/2015,21/11/2018 10:58,14/04/2020 08:35,,7110-7120,,20,42,,,,,,,,,,,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4HXW4E7Q,journalArticle,2015,"Cappanera, Paola; Scutella, Maria Grazia","Joint Assignment, Scheduling, and Routing Models to Home Care Optimization: A Pattern-Based Approach",TRANSPORTATION SCIENCE,,0041-1655,10.1287/trsc.2014.0548,,"The design of efficient home care services is a quite recent and challenging field of study. We propose an integrated approach that jointly addresses: (i) the assignment of operators to patients so as to guarantee the compatibility between skills associated with operators and patient visits; (ii) the scheduling of the visits in a given planning horizon; and (iii) the determination of the operator tours in every day of the planning horizon. The main home care problem we investigate refers to providers dedicated to palliative care and terminal patients. In this context, balancing objective functions are particularly relevant. Therefore, two balancing functions are studied, i.e., maxmin, which maximizes the minimum operator utilization factor, and minmax, which minimizes the maximum operator utilization factor. In both cases, the concept of pattern is introduced as a key tool to jointly address assignment, scheduling, and routing decisions, where a pattern specifies a possible schedule for skilled visits. The approach we propose is, however, able to cope with peculiarities from other home care contexts. Model extensions to handle scenarios other than the palliative one are discussed in the paper. Extensive computational results are reported both on palliative home care instances based on real data, and on two real-world data sets from the literature, related to contexts very different from the palliative one. For both data sets the proposed approach is able to find solutions of good quality. In the palliative context, the results show that the selection of the pattern generation policy is crucial to solve large instances efficiently. Furthermore, the maxmin criterion is able to return more balanced solutions; i.e., the difference between the maximum and the minimum operator utilization factors is very small. On the other hand, the minmax criterion is more suitable for minimizing the operating costs, since it computes solutions with smaller total traveled time.",2015-11,21/11/2018 10:58,14/04/2020 08:34,,830-852,,4,49,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 67877AY6,journalArticle,2015,"Wijeyekoon, Skanda; Kharicha, Kalpa; Iliffe, Steve",Heuristics in primary care for recognition of unreported vision loss in older people: a technology development study,PRIMARY HEALTH CARE RESEARCH AND DEVELOPMENT,,1463-4236,10.1017/S1463423614000425,,"Aim: To evaluate heuristics (rules of thumb) for recognition of undetected vision loss in older patients in primary care. Background: Vision loss is associated with ageing, and its prevalence is increasing. Visual impairment has a broad impact on health, functioning and well-being. Unrecognised vision loss remains common, and screening interventions have yet to reduce its prevalence. An alternative approach is to enhance practitioners' skills in recognising undetected vision loss, by having a more detailed picture of those who are likely not to act on vision changes, report symptoms or have eye tests. This paper describes a qualitative technology development study to evaluate heuristics for recognition of undetected vision loss in older patients in primary care. Method: Using a previous modelling study, two heuristics in the form of mnemonics were developed to aid pattern recognition and allow general practitioners to identify potential cases of unreported vision loss. These heuristics were then analysed with experts. Findings: It was concluded that their implementation in modern general practice was unsuitable and an alternative solution should be sort.",2015-09,21/11/2018 10:58,14/04/2020 08:35,,429-435,,5,16,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EE2DBPAC,journalArticle,2015,"Ramirez-Nafarrate, Adrian; Lyon, Joshua D.; Fowler, John W.; Araz, Ozgur M.",Point-of-Dispensing Location and Capacity Optimization via a Decision Support System,PRODUCTION AND OPERATIONS MANAGEMENT,,1059-1478,10.1111/poms.12323,,Dispensing of mass prophylaxis can be critical to public health during emergency situations and involves complex decisions that must be made in a short period of time. This study presents a model and solution approach for optimizing point-of-dispensing (POD) location and capacity decisions. This approach is part of a decision support system designed to help officials prepare for and respond to public health emergencies. The model selects PODs from a candidate set and suggests how to staff each POD so that average travel and waiting times are minimized. A genetic algorithm (GA) quickly solves the problem based on travel and queuing approximations (QAs) and it has the ability to relax soft constraints when the dispensing goals cannot be met. We show that the proposed approach returns solutions comparable with other systems and it is able to evaluate alternative courses of action when the resources are not sufficient to meet the performance targets.,2015-08,21/11/2018 10:58,14/04/2020 08:35,,1311-1328,,8,24,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2EDBTFBK,journalArticle,2015,"Herman, William H.; Ye, Wen; Griffin, Simon J.; Simmons, Rebecca K.; Davies, Melanie J.; Khunti, Kamlesh; Rutten, Guy E. H. M.; Sandbaek, Annelli; Lauritzen, Torsten; Borch-Johnsen, Knut; Brown, Morton B.; Wareham, Nicholas J.",Early Detection and Treatment of Type 2 Diabetes Reduce Cardiovascular Morbidity and Mortality: A Simulation of the Results of the Anglo-Danish-Dutch Study of Intensive Treatment in People With Screen-Detected Diabetes in Primary Care (ADDITION-Europe),DIABETES CARE,,0149-5992,10.2337/dc14-2459,,"OBJECTIVE To estimate the benefits of screening and early treatment of type 2 diabetes compared with no screening and late treatment using a simulation model with data from the ADDITION-Europe study. RESEARCH DESIGN AND METHODS We used the Michigan Model, a validated computer simulation model, and data from the ADDITION-Europe study to estimate the absolute risk of cardiovascular outcomes and the relative risk reduction associated with screening and intensive treatment, screening and routine treatment, and no screening with a 3- or 6-year delay in the diagnosis and routine treatment of diabetes and cardiovascular risk factors. RESULTS When the computer simulation model was programmed with the baseline demographic and clinical characteristics of the ADDITION-Europe population, it accurately predicted the empiric results of the trial. The simulated absolute risk reduction and relative risk reduction were substantially greater at 5 years with screening, early diagnosis, and routine treatment compared with scenarios in which there was a 3-year (3.3% absolute risk reduction [ARR], 29% relative risk reduction [RRR]) or a 6-year (4.9% ARR, 38% RRR) delay in diagnosis and routine treatment of diabetes and cardiovascular risk factors. CONCLUSIONS Major benefits are likely to accrue from the early diagnosis and treatment of glycemia and cardiovascular risk factors in type 2 diabetes. The intensity of glucose, blood pressure, and cholesterol treatment after diagnosis is less important than the time of its initiation. Screening for type 2 diabetes to reduce the lead time between diabetes onset and clinical diagnosis and to allow for prompt multifactorial treatment is warranted.",2015-08,21/11/2018 10:58,14/04/2020 08:34,,1449-1455,,8,38,,,,,,,,,,,,,,,,,,,,,00; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XN2B9CTF,journalArticle,2015,"Sahin, Evren; Matta, Andrea",A contribution to operations management-related issues and models for home care structures,INTERNATIONAL JOURNAL OF LOGISTICS-RESEARCH AND APPLICATIONS,,1367-5567,10.1080/13675567.2014.946560,,"Health services provided at home are becoming more important in most European countries. A better understanding of the specificities of home care (HC) operations and their management is therefore necessary. The importance of operations management for HC is obvious; such systems are faced with a growing demand for care and higher expectations for improved service delivery with more and more constraints on available budget and resources. Based on interviews of HC practices in France and Italy as well as an international review of the literature related to HC operations, this paper aims at contributing to a better characterisation of HC operations and the associated decision-making models. The main part of the presentation is made at a generic level and the paper includes also a more specific part on the chemotherapy at home process. We also provide a discussion on the most relevant research topics in the field of HC operations management.",04/07/2015,21/11/2018 10:58,14/04/2020 08:35,,355-385,,4,18,,,,,,,,,,,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WA8CZ5HK,journalArticle,2015,"Hazen, Ankie C. M.; Sloeserwij, Vivianne M.; Zwart, Dorien L. M.; de Bont, Antoinette A.; Bouvy, Marcel L.; de Gier, Johan J.; de Wit, Niek J.; Leendertse, Anne J.",Design of the POINT study: Pharmacotherapy Optimisation through Integration of a Non-dispensing pharmacist in a primary care Team (POINT),BMC FAMILY PRACTICE,,1471-2296,10.1186/s12875-015-0296-8,,"Background: In the Netherlands, 5.6 % of acute hospital admissions are medication-related. Almost half of these admissions are potentially preventable. Reviewing medication in patients at risk in primary care might prevent these hospital admissions. At present, implementation of medication reviews in primary care is suboptimal: pharmacists lack access to patient information, pharmacists are short of clinical knowledge and skills, and working processes of pharmacists (focus on dispensing) and general practitioners (focus on clinical practice) match poorly. Integration of the pharmacist in the primary health care team might improve pharmaceutical care outcomes. The aim of this study is to evaluate the effect of integration of a non-dispensing pharmacist in general practice on the safety of pharmacotherapy in the Netherlands. Methods: The POINT study is a non-randomised controlled intervention study with pre-post comparison in an integrated primary care setting. We compare three different models of pharmaceutical care provision in primary care: 1) a non-dispensing pharmacist as an integral member of a primary care team, 2) a pharmacist in a community pharmacy with a predefined training in performing medication reviews and 3) a pharmacist in a community pharmacy (care as usual). In all models, GPs remain accountable for individual medication prescription. In the first model, ten non-dispensing clinical pharmacists are posted in ten primary care practices (including 5 - 10 000 patients each) for a period of 15 months. These non-dispensing pharmacists perform patient consultations, including medication reviews, and share responsibility for the pharmaceutical care provided in the practice. The two other groups consist of ten primary care practices with collaborating pharmacists. The main outcome measurement is the number of medication-related hospital admissions during follow-up. Secondary outcome measurements are potential medication errors, drug burden index and costs. Parallel to this study, a qualitative study is conducted to evaluate the feasibility of introducing a NDP in general practice. Discussion: As the POINT study is a large-scale intervention study, it should provide evidence as to whether integration of a non-dispensing clinical pharmacist in primary care will result in safer pharmacotherapy. The qualitative study also generates knowledge on the optimal implementation of this model in primary care. Results are expected in 2016.",02/07/2015,21/11/2018 10:58,14/04/2020 08:34,,,,,16,,,,,,,,,,,,,,,,,,,,,"Humans; Netherlands; Professional Role; Polypharmacy; Patient Care Team/*organization & administration; Primary Health Care/*organization & administration; Hospitalization/statistics & numerical data; 00; Delivery of Health Care, Integrated/*organization & administration; Clinical Protocols; Community Pharmacy Services; General Practice/organization & administration; Medication Errors/*prevention & control/statistics & numerical data; Pharmaceutical Services/*organization & administration; Pharmacists/*organization & administration; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FYJJR7IX,journalArticle,2015,"Diaz, Rafael; Behr, Joshua G.; Britton, Bruce S.",Estimating cost adjustments required to accomplish target savings in chronic disease management interventions: a simulation study,SIMULATION-TRANSACTIONS OF THE SOCIETY FOR MODELING AND SIMULATION INTERNATIONAL,,0037-5497,10.1177/0037549715584618,,"Chronic diseases are persistent ailments that are not preventable or curable with medication or vaccination. Many of the leading chronic conditions in industrialized societies may be related to lifestyle choices. The prevalence of these chronic conditions significantly affects the health, suffering, and longevity of patients. This paper demonstrates the utility of system dynamics as an approach to model and simulate the behavior of key cost factors in the implementation of population health management interventions. The study uses modeling and simulation as an evaluative method to identify potential savings stemming from an intervention within a well-defined population group. The model is flexible in that it allows policy-makers the ability to set saving targets that, in turn, generate knowledge about the cost structure adjustments necessary to reach these targets. The model provides useful insights into how the initial estimates of the cost of intervention, the resulting savings, and potential costs adjustments may change. The functionality of the model is demonstrated by means of scenarios implemented via sensitivity analysis.",2015-07,21/11/2018 10:58,14/04/2020 08:34,,599-614,,7,91,,,,,,,,,,,,,,,,,,,,,System dynamics; 1; 310,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XQ855GWV,journalArticle,2015,"Gittelsohn, Joel; Mui, Yeeli; Adam, Atif; Lin, Sen; Kharmats, Anna; Igusa, Takeru; Lee, Bruce Y.","Incorporating Systems Science Principles into the Development of Obesity Prevention Interventions: Principles, Benefits, and Challenges",CURRENT OBESITY REPORTS,,2162-4968,10.1007/s13679-015-0147-x,,"Systems modeling represents an innovative approach for addressing the obesity epidemic at the community level. We developed an agent-based model of the Baltimore City food environment that permits us to assess the relative impact of different programs and policies, alone and in combination, and potential unexpected consequences. Based on this experience, and a review of literature, we have identified a set of principles, potential benefits, and challenges. Some of the key principles include the importance of early and multilevel engagement with the community prior to initiating model development and continued engagement and testing with community stakeholders. Important benefits include improving community stakeholder understanding of the system, testing of interventions before implementation, and identification of unexpected consequences. Challenges in these models include deciding on the most important, yet parsimonious factors to consider, how to model food source and food selection behavior in a realistic yet transferable manner, and identifying the appropriate outcomes and limitations of the model.",2015-06,21/11/2018 10:58,14/04/2020 08:34,,174-181,,2,4,,,,,,,,,,,,,,,,,,,,,1; System Analysis; agent based; 210,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UMDE6YEY,journalArticle,2015,"Brittin, J.; Araz, O. M.; Nam, Y.; Huang, T. T-K",A system dynamics model to simulate sustainable interventions on chronic disease outcomes in an urban community,JOURNAL OF SIMULATION,,1747-7778,10.1057/jos.2014.16,,"Socio-demographics of urban US populations have been associated with poor health status and chronic disease. Patterns of rising chronic disease prevalence have persisted in populations with lower socio-economic status despite substantial and costly public health efforts to the contrary. In this paper, we used a system dynamics model to simulate chronic disease prevalence, along with potential interventions, for a low-income urban community in Chicago, Illinois. We hypothesized that the `triple bottom line' of sustainability-addressing economic, social, and environmental issues-would be key to mitigation and reduction of chronic disease over time in such a community. The aim was to inform decision making about urban design and public health programme planning towards formulation of approaches-some beyond the traditional boundaries of health interventions-to improve community chronic disease outcomes over time. We found that single interventions on the constructs of Income and Employment, Neighbourhood Attractiveness, and Social Cohesion were most impactful in reducing or reversing the rise of chronic disease prevalence. Increasing Housing Capacity allowed the Neighbourhood Attractiveness intervention to have a greater impact. In addition, interventions in Neighbourhood Attractiveness and Chronic Disease Prevention produced a greater combined mitigating effect on chronic disease prevalence than the sum of the individual intervention effects. Findings suggest that socio-environmental conditions should be addressed, with consideration of population migration dynamics, in formulating viable and sustainable solutions to improve community-level health outcomes such as chronic disease prevalence.",2015-05,21/11/2018 10:58,14/04/2020 08:34,,140-155,,"2, SI",9,,,,,,,,,,,,,,,,,,,,,System dynamics; 1; 320,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3YABBCUI,journalArticle,2015,"Lima, Viviane D.; Graf, Isabell; Beckwith, Curt G.; Springer, Sandra; Altice, Frederick L.; Coombs, Daniel; Kim, Brian; Messina, Lauren; Montaner, Julio S. G.; Spaulding, Anne","The Impact of Implementing a Test, Treat and Retain HIV Prevention Strategy in Atlanta among Black Men Who Have Sex with Men with a History of Incarceration: A Mathematical Model",PLOS ONE,,1932-6203,10.1371/journal.pone.0123482,,"Background Annually, 10 million adults transition through prisons or jails in the United States (US) and the prevalence of HIV among entrants is three times higher than that for the country as a whole. We assessed the potential impact of increasing HIV Testing/Treatment/Retention (HIV-TTR) in the community and within the criminal justice system (CJS) facilities, coupled with sexual risk behavior change, focusing on black men-who-have-sex-with-men, 15-54 years, in Atlanta, USA. Methods We modeled the effect of a HIV-TTR strategy on the estimated cumulative number of new (acquired) infections and mortality, and on the HIV prevalence at the end of ten years. We additionally assessed the effect of increasing condom use in all settings. Results In the Status Quo scenario, at the end of 10 years, the cumulative number of new infections in the community, jail and prison was, respectively, 9246, 77 and 154 cases; HIV prevalence was 10815, 69 and 152 cases, respectively; and the cumulative number of deaths was 2585, 18 and 34 cases, respectively. By increasing HIV-TTR coverage, the cumulative number of new infections could decrease by 15% in the community, 19% in jail, and 8% in prison; HIV prevalence could decrease by 8%, 9% and 7%, respectively; mortality could decrease by 20%, 39% and 18%, respectively. Based on the model results, we have shown that limited use and access to condoms have contributed to the HIV incidence and prevalence in all settings. Conclusions Aggressive implementation of a CJS-focused HIV-TTR strategy has the potential to interrupt HIV transmission and reduce mortality, with benefit to the community at large. To maximize the impact of these interventions, retention in treatment, including during the period after jail and prison release, and increased condom use was vital for decreasing the burden of the HIV epidemic in all settings.",23/04/2015,21/11/2018 10:58,14/04/2020 08:34,,,,4,10,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IYEQEHE2,journalArticle,2015,"Iizuka, Makito; Tomita, Kazuhide; Takeshima, Reiko",Experience-oriented tobacco-use prevention lecture using a COPD-simulation mask for junior high school students,RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY,,1569-9048,10.1016/j.resp.2014.09.012,,"We recently developed a mask that simulates the experience of having one of the major diseases caused by tobacco smoking: chronic obstructive pulmonary disease (COPD). Here we examined the effects of a tobacco-use prevention lecture accompanied by a pseudo-COPD experience created with this mask on adolescents' attitude toward smoking. Junior high school students (12-13 years old, n = 165) in Japan were the subjects. The students attended a 30-min tobacco-use prevention lecture with slides and movie clips and engaged in a light exercise session wearing the COPD-simulation mask for 15 min. Before and after the lecture, the students' attitudes toward smoking were evaluated by the Kano test for social nicotine dependence (KTSND). The total KTSND scores decreased significantly from 9.9 +/- 4.4 (mean +/- SD, n = 149) to 7.5 +/- 5.3 (n = 144). Ninety-eight students wore the COPD mask, and their modified Borg scale scores increased significantly from 0.7 +/- 1.0 to 3.2 +/- 2.1 after exercise (P < 0.0001). To the questionnaire item “Do you think you understand the suffering of individuals with COPD?”, 24 and 51 students answered “definitely yes” and “yes”, whereas 16, 4 and 1 answered “Cannot say,” “no” and “definitely no”, respectively. The KTSND scores were significantly smaller in the former affirmative group compared to the latter negative group (P < 0.05). Of the 98 students who wore the simulation mask, 83 reported being satisfied with this pseudo-COPD experience. The tobacco-use prevention lecture with the pseudo-COPD experience created by the simulation mask was effective and safe. (C) 2014 Elsevier B.V. All rights reserved.",2015-04,21/11/2018 10:58,14/04/2020 08:34,,28-32,,SI,209,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KBZQLP4L,journalArticle,2015,"Gandjour, Afschin; Tschulena, Ulrich; Steppan, Sonja; Gatti, Emanuele",A simulation model to estimate cost-offsets for a disease-management program for chronic kidney disease,EXPERT REVIEW OF PHARMACOECONOMICS & OUTCOMES RESEARCH,,1473-7167,10.1586/14737167.2015.972375,,"Aim: The aim of this paper is to develop a simulation model that analyzes cost-offsets of a hypothetical disease management program (DMP) for patients with chronic kidney disease (CKD) in Germany compared to no such program. Methods: A lifetime Markov model with simulated 65-year-old patients with CKD was developed using published data on costs and health status and simulating the progression to end-stage renal disease (ESRD), cardiovascular disease and death. A statutory health insurance perspective was adopted. Results: This modeling study shows considerable potential for cost-offsets from a DMP for patients with CKD. The potential for cost-offsets increases with relative risk reduction by the DMP and baseline glomerular filtration rate. Results are most sensitive to the cost of dialysis treatment. Conclusion: This paper presents a general `prototype' simulation model for the prevention of ESRD. The model allows for further modification and adaptation in future applications.",2015-04,21/11/2018 10:58,14/04/2020 08:34,,341-347,,2,15,,,,,,,,,,,,,,,,,,,,,"Humans; *Models, Economic; Aged; *Markov Chains; Disease Progression; Germany; 1; chronic kidney disease; disease management; Glomerular Filtration Rate; Insurance, Health/economics; Kidney Failure, Chronic/economics/prevention & control; Renal Dialysis/economics; Renal Insufficiency, Chronic/economics/physiopathology/*therapy; simulation model; 320",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 546U4SQ2,conferencePaper,2015,"Lelis Carvalho, Viviane Maria",An Agent-Based Decision Support Environment for Public Health,"TRENDS IN PRACTICAL APPLICATIONS OF AGENTS, MULTI-AGENT SYSTEMS AND SUSTAINABILITY: THE PAAMS COLLECTION",978-3-319-19629-9 978-3-319-19628-2,,10.1007/978-3-319-19629-9_26,,"Decision support systems can be quite useful in public health management since it can provide new and relevant information regarding to population profile, incidence and behavior of diseases over time, as well as effectiveness of prevention methods. Such systems may also be useful if they are able to make predictions and trigger alerts about future events. Meningitis is an infectious disease with high mortality rate, especially in less devel-oped countries.",2015,21/11/2018 10:58,14/04/2020 08:34,,229-230,,,372,,,,Advances in Intelligent Systems and Computing,,,,"IBM; IEEE Syst Man & Cybernet Soc Spain; AEPIA; Assoc Francaise Intelligence Artificielle; AAAI; APPIA; ARIA; ATIA; BNVKI,; SADIO; Soc Brasileira Computacao; GI; Univ Salamanca; CNRS; Portuguese Assoc Artificial Intelligence; Telefonica; Bioinformat Intelligent Syst & Educ Technol Res Grp; Junta Castilla Leon; Univ Salamanca; indra",,,,,,,,,,"

13th International Conference on Practical Applications of Agents, Multi-Agent Systems, and Sustainability (PAAMS), Salamanca, SPAIN, JUN 03-05, 2015

",,,1; Agent Based; 100,,"Bajo, J and Hernandez, JZ and Mathieu, P and Campbell, A and FernandezCaballero, A and Moreno, MN and Julian, V and AlonsoBetanzos, A and JimenezLopez, MD and Botti, V",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, D9B49HHV,journalArticle,2015,"Liaw, Sok Ying; Wong, Lai Fun; Chan, Sally Wai-Chi; Ho, Jasmine Tze Yin; Mordiffi, Siti Zubaidah; Ang, Sophia Bee Leng; Goh, Poh Sun; Ang, Emily Neo Kim",Designing and Evaluating an Interactive Multimedia Web-Based Simulation for Developing Nurses' Competencies in Acute Nursing Care: Randomized Controlled Trial,JOURNAL OF MEDICAL INTERNET RESEARCH,,1438-8871,10.2196/jmir.3853,,"Background: Web-based learning is becoming an increasingly important instructional tool in nursing education. Multimedia advancements offer the potential for creating authentic nursing activities for developing nursing competency in clinical practice. Objective: This study aims to describe the design, development, and evaluation of an interactive multimedia Web-based simulation for developing nurses' competencies in acute nursing care. Methods: Authentic nursing activities were developed in a Web-based simulation using a variety of instructional strategies including animation video, multimedia instructional material, virtual patients, and online quizzes. A randomized controlled study was conducted on 67 registered nurses who were recruited from the general ward units of an acute care tertiary hospital. Following a baseline evaluation of all participants' clinical performance in a simulated clinical setting, the experimental group received 3 hours of Web-based simulation and completed a survey to evaluate their perceptions of the program. All participants were re-tested for their clinical performances using a validated tool. Results: The clinical performance posttest scores of the experimental group improved significantly (P<.001) from the pretest scores after the Web-based simulation. In addition, compared to the control group, the experimental group had significantly higher clinical performance posttest scores (P<.001) after controlling the pretest scores. The participants from the experimental group were satisfied with their learning experience and gave positive ratings for the quality of the Web-based simulation. Themes emerging from the comments about the most valuable aspects of the Web-based simulation include relevance to practice, instructional strategies, and fostering problem solving. Conclusions: Engaging in authentic nursing activities using interactive multimedia Web-based simulation can enhance nurses' competencies in acute care. Web-based simulations provide a promising educational tool in institutions where large groups of nurses need to be trained in acute nursing care and accessibility to repetitive training is essential for achieving long-term retention of clinical competency.",2015-01,21/11/2018 10:58,14/04/2020 08:34,,,,1,17,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8963P7DL,conferencePaper,2015,"Nickel, Peter; Proeger, Eugen; Lungfiel, Andy; Kergel, Rolf","Flexible, dynamic VR simulation of a future river lock facilitates prevention through design in occupational safety and health",2015 IEEE VIRTUAL REALITY CONFERENCE (VR),978-1-4799-1727-3,,,,"Industry and services have a growing interest in prevention through design with regard to safety of machinery to avoid redesign after construction. A VR planning model of a future river lock has been developed and investigated for risk assessment support. Inspections using the model in 1:1 scale promoted safety analyses of the operational concept, identified hazards and planning flaws, and triggered measures for reducing risks of the future lock. VR simulation contributed to occupational safety and health early in machinery design while saving effort and time.",2015,21/11/2018 10:58,14/04/2020 08:35,,385-386,,,,,,,Proceedings of the IEEE Virtual Reality Annual International Symposium,,,,IEEE; IEEE Comp Soc; IEEE Comp Soc Visualizat & Graph Tech Comm; IEEE France,,,,,,,,,,"

22nd IEEE Virtual Reality Conference (VR), Arles, FRANCE, MAR 23-27, 2015

",,,00; 100,,"Hollerer, T and Interrante, V and Lecuyer, A and Swan, JE",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7YQ9ZU5Y,conferencePaper,2015,"Widmer, Tobias; Premm, Marc",Agent-Based Decision Support for Allocating Caregiving Resources in a Dementia Scenario,"MULTIAGENT SYSTEM TECHNOLOGIES, MATES 2015",978-3-319-27343-3 978-3-319-27342-6,,10.1007/978-3-319-27343-3_13,,"Due to the increasing number of Dementia patients, the overall costs for caregiving has grown by 32 % between 2002 and 2008. The efficient use of smart decision support systems for managing ambulant care and mobile nursing services that provide professional care for Dementia patients is an important challenge to reduce cost and increase service quality. The optimal allocation of caregiving resources from different mobile nursing service firms to a growing number of Dementia patients, however, is a difficult problem in the healthcare domain. We approach this problem from a multiagent systems perspective by designing and implementing a distributed decision support system that utilizes an auction-based protocol for allocating caregiving resources subject to Dementia-specific service attributes. We demonstrate the usefulness of the proposed protocol by an early stage prototype implementation presenting the system's proof-of-concept.",2015,21/11/2018 10:58,14/04/2020 08:35,,233-248,,,9433,,,,Lecture Notes in Artificial Intelligence,,,,German Soc Informat,,,,,,,,,,"

13th German Conference on Multiagent System Technologies (MATES), Cottbus, GERMANY, SEP 28-30, 2015

",,,00; 110,,"Muller, JP and Ketter, W and Kaminka, G and Wagner, G and Bulling, N",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, L5F4XK3S,conferencePaper,2015,"Cardoso, T.; Oliveira, M. D.; Barbosa-Povoa, A.; Nickel, S.",Introducing health gains in location-allocation models: A stochastic model for planning the delivery of long-term care,"MINI EURO CONFERENCE ON IMPROVING HEALTHCARE: NEW CHALLENGES, NEW APPROACHES",,,10.1088/1742-6596/616/1/012007,,"Although the maximization of health is a key objective in health care systems, location-allocation literature has not yet considered this dimension. This study proposes a multi-objective stochastic mathematical programming approach to support the planning of a multi-service network of long-term care (LTC), both in terms of services location and capacity planning. This approach is based on a mixed integer linear programming model with two objectives - the maximization of expected health gains and the minimization of expected costs - with satisficing levels in several dimensions of equity - namely, equity of access, equity of utilization, socioeconomic equity and geographical equity - being imposed as constraints. The augmented epsilon-constraint method is used to explore the trade-off between these conflicting objectives, with uncertainty in the demand and delivery of care being accounted for. The model is applied to analyze the (re) organization of the LTC network currently operating in the Great Lisbon region in Portugal for the 2014-2016 period. Results show that extending the network of LTC is a cost-effective investment.",2015,21/11/2018 10:58,14/04/2020 08:34,,,,,616,,,,Journal of Physics Conference Series,,,,Assoc European Operat Res Soc,,,,,,,,,,"

31st EURO Mini Conference on Improving Healthcare - New Challenges, New Approaches, Coimbra, PORTUGAL, MAR 30-APR 01, 2015

",,,mathematical modeling; 1; operational research; Stochastic modeling; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QHF3HJKZ,conferencePaper,2015,"Norouzzadeh, Shaghayegh; Riebling, Nancy; Carter, Lawrence; Conigliaro, Joseph; Doerfler, Martin E.",SIMULATION MODELING TO OPTIMIZE HEALTH CARE DELIVERY IN AN OUTPATIENT CLINIC,2015 WINTER SIMULATION CONFERENCE (WSC),978-1-4673-9743-8,,,,"This paper presents a comprehensive exploration of an Internal Medicine outpatient clinic practice setting by applying discrete event simulation (DES) modeling. Growing demands on outpatient clinics require greater emphasis on enhancing performance and optimizing resource utilization. Therefore, a data collection plan was designed to capture total patient visit time; including waiting, clinical care, and clinical administrative time. The collected data was fed into a DES model. The model was validated through a statistical comparison with the performance of the real system. Various improvement alternatives were then proposed and investigated through the DES model, such as altering resource allocation, patient rooming and prioritization, and patient volume. For each scenario, key performance indicators of the system, resource utilization metrics, capacity metrics and turnaround time metrics were traced. Findings indicated that targeted improvement scenarios could be applied with 27.5%, 54.8% and 20% enhancement in utilization, capacity and turnaround time respectively.",2015,21/11/2018 10:58,14/04/2020 08:34,,1355-1366,,,,,,,Winter Simulation Conference Proceedings,,,,,,,,,,,,,,"

Winter Simulation Conference (WSC), Huntington Beach, CA, DEC 06-09, 2015

",,,1; Discrete event; 310,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QA2QHW8C,conferencePaper,2015,"Bastos, Bruno; Heleno, Tiago; Trigo, Antonio; Martins, Pedro",Web Based Application for Home Care Visits' Optimization of Health Professionals' Teams of Health Centers,OPERATIONAL RESEARCH: IO 2013 - XVI CONGRESS OF APDIO,978-3-319-20328-7 978-3-319-20327-0,,10.1007/978-3-319-20328-7_3,,"Health Centers have among one of their many tasks the provision of health care at home. This service is provided by teams of health professionals, usually composed of physicians and nurses belonging to the Health Centers. The scheduling of the visits is made by a health professional that groups one or more routes in order to minimize the time of team's visits. However, as there is no technical or computer application to plan and optimize the visits in a systematic way, the obtained solutions are rarely the best ones. To improve this situation we were challenged by a Health Center to create an application to optimize the visits of health care professionals. This paper presents the solution developed involving a web application called “Health at Home”, which uses the heuristic of Clarke and Wright. The main novelty of this work is the inclusion of priority and non-priority patients, according to their degree of aseptic, within the routes optimization of the health professionals' teams.",2015,21/11/2018 10:58,14/04/2020 08:34,,37-52,,,4,,,,CIM Series in Mathematical Sciences,,,,Associacao Portuguesa Investigacao Operac,,,,,,,,,,"

16th National Conference of the APDIO, Braganca, PORTUGAL, JUN 03-05, 2013

",,,00; 110,,"Almeida, JP and Oliveira, JF and Pinto, AA",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RIAJJXPG,journalArticle,2014,"Edmonds, Brownsyne Tucker; McKenzie, Fatima; Fadel, William F.; Matthias, Marianne S.; Salyers, Michelle P.; Barnato, Amber E.; Frankel, Richard M.",Using Simulation to Assess the Influence of Race and Insurer on Shared Decision Making in Periviable Counseling,SIMULATION IN HEALTHCARE-JOURNAL OF THE SOCIETY FOR SIMULATION IN HEALTHCARE,,1559-2332,10.1097/SIH.0000000000000049,,"Introduction Sociodemographic differences have been observed in the treatment of extremely premature (periviable) neonates, but the source of this variation is not well understood. We assessed the feasibility of using simulation to test the effect of maternal race and insurance status on shared decision making (SDM) in periviable counseling. Methods We conducted a 2 x 2 factorial simulation experiment in which obstetricians and neonatologists counseled 2 consecutive standardized patients diagnosed with ruptured membranes at 23 weeks, counterbalancing race (black/white) and insurance status using random permutation. We assessed verisimilitude of the simulation in semistructured debriefing interviews. We coded physician communication related to resuscitation, mode of delivery, and steroid decisions using a 9-point SDM coding framework and then compared communication scores by standardized patient race and insurer using analysis of variance. Results Sixteen obstetricians and 15 neonatologists participated; 71% were women, 84% were married, and 75% were parents; 91% of the physicians rated the simulation as highly realistic. Overall, SDM scores were relatively high, with means ranging from 6.4 to 7.9 (of 9). There was a statistically significant interaction between race and insurer for SDM related to steroid use and mode of delivery (P < 0.01 and P = 0.01, respectively). Between-group comparison revealed nonsignificant differences (P = <0.10) between the SDM scores for privately insured black patients versus privately insured white patients, Medicaid-insured white patients versus Medicaid-insured black patients, and privately insured black patients versus Medicaid-insured black patients. Conclusions This study confirms that simulation is a feasible method for studying sociodemographic effects on periviable counseling. Shared decision making may occur differentially based on patients' sociodemographic characteristics and deserves further study.",2014-12,21/11/2018 10:58,14/04/2020 08:34,,353-359,,6,9,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6FGPA9IU,journalArticle,2014,"Brookmeyer, Ron; Boren, David; Baral, Stefan D.; Bekker, Linda-Gail; Phaswana-Mafuya, Nancy; Beyrer, Chris; Sullivan, Patrick S.",Combination HIV Prevention among MSM in South Africa: Results from Agent-based Modeling,PLOS ONE,,1932-6203,10.1371/journal.pone.0112668,,"HIV prevention trials have demonstrated the effectiveness of a number of behavioral and biomedical interventions. HIV prevention packages are combinations of interventions and offer potential to significantly increase the effectiveness of any single intervention. Estimates of the effectiveness of prevention packages are important for guiding the development of prevention strategies and for characterizing effect sizes before embarking on large scale trials. Unfortunately, most research to date has focused on testing single interventions rather than HIV prevention packages. Here we report the results from agent-based modeling of the effectiveness of HIV prevention packages for men who have sex with men (MSM) in South Africa. We consider packages consisting of four components: antiretroviral therapy for HIV infected persons with CD4 count <350; PrEP for high risk uninfected persons; behavioral interventions to reduce rates of unprotected anal intercourse (UAI); and campaigns to increase HIV testing. We considered 163 HIV prevention packages corresponding to different intensity levels of the four components. We performed 2252 simulation runs of our agent-based model to evaluate those packages. We found that a four component package consisting of a 15% reduction in the rate of UAI, 50% PrEP coverage of high risk uninfected persons, 50% reduction in persons who never test for HIV, and 50% ART coverage over and above persons already receiving ART at baseline, could prevent 33.9% of infections over 5 years (95% confidence interval, 31.5, 36.3). The package components with the largest incremental prevention effects were UAI reduction and PrEP coverage. The impact of increased HIV testing was magnified in the presence of PrEP. We find that HIV prevention packages that include both behavioral and biomedical components can in combination prevent significant numbers of infections with levels of coverage, acceptance and adherence that are potentially achievable among MSM in South Africa.",14/11/2014,21/11/2018 10:58,14/04/2020 08:34,,,,11,9,,,,,,,,,,,,,,,,,,,,,1; Agent-based model; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 248TRV6L,journalArticle,2014,"Dunbar, Martin X.; Samawi, Hani M.; Vogel, Robert; Yu, Lili",A more efficient Gibbs sampler estimation using steady-state simulation: applications to public health studies,JOURNAL OF STATISTICAL COMPUTATION AND SIMULATION,,0094-9655,10.1080/00949655.2013.770857,,"Markov chain Monte Carlo methods, in particular, the Gibbs sampler, are widely used algorithms both in application and theoretical works in the classical and Bayesian paradigms. However, these algorithms are often computer intensive. Samawi et al. [Steady-state ranked Gibbs sampler. J. Stat. Comput. Simul. 2012;82(8), 1223-1238. doi:10.1080/00949655.2011.575378] demonstrate through theory and simulation that the dependent steady-state Gibbs sampler is more efficient and accurate in model parameter estimation than the original Gibbs sampler. This paper proposes the independent steady-state Gibbs sampler (ISSGS) approach to improve the original Gibbs sampler in multidimensional problems. It is demonstrated that ISSGS provides accuracy with unbiased estimation and improves the performance and convergence of the Gibbs sampler in multidimensional problems.",02/09/2014,21/11/2018 10:58,14/04/2020 08:34,,1931-1945,,9,84,,,,,,,,,,,,,,,,,,,,,******To read; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, A2H3FYV8,journalArticle,2014,"Shi, Jing; Peng, Yidong; Erdem, Ergin",Simulation analysis on patient visit efficiency of a typical VA primary care clinic with complex characteristics,SIMULATION MODELLING PRACTICE AND THEORY,,1569-190X,10.1016/j.simpat.2014.06.003,,"In this paper, we develop a simulation model to study the performance of clinic operations based on the settings of a typical VA primary care clinic with complex characteristics. The clinic serves three different types of patients, namely, regular appointment patients, walk-in patients, and nurse-only patients, and they each have different patient flow routes. The model captures the patient flow characteristics of the studied clinic, and it is validated by comparing the simulation results with the real key performance measures obtained from in the clinic. The system performance is mainly measured by two metrics: one is how the clinic makes efficient use of its resources, and the other is how long the patients need to wait for services. A scenario analysis is conducted which adopts the experiment design method for multiple factors to study the effect of six parameters on the system performance. The six parameters are walk-in arrival rate, no-show rate, post-triage rate, new patient rate, number of double booking, and nurse-only appointment rate. Based on the results, one major recommendation for the clinic is to reduce or eliminate the use of double booking because it causes the dramatic increase of patient waiting time. Also, based on the projection of the high new patient rate in the near future, it is recommended that the clinic manage the walk-in patient load by adjusting the existing admission policy. In addition, for the clinic with already high provider utilization, interventions for reducing patient no-show rate alone may further deteriorate the congestion of patient visit in the clinic. (C) 2014 Elsevier B.V. All rights reserved.",2014-09,21/11/2018 10:58,14/04/2020 08:35,,165-181,,,47,,,,,,,,,,,,,,,,,,,,,100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TEUNEHRZ,journalArticle,2014,"Slejko, Julia F.; Sullivan, Patrick W.; Anderson, Heather D.; Ho, P. Michael; Nair, Kavita V.; Campbell, Jonathan D.",Dynamic Medication Adherence Modeling in Primary Prevention of Cardiovascular Disease: A Markov Microsimulation Methods Application,VALUE IN HEALTH,,1098-3015,10.1016/j.jval.2014.06.010,,"Background: Real-world patients' medication adherence is lower than that of clinical trial patients. Hence, the effectiveness of medications in routine practice may differ. Objectives: The study objective was to compare the outcomes of an adherence-naive versus a dynamic adherence modeling framework using the case of statins for the primary prevention of cardiovascular (CV) disease. Methods: Statin adherence was categorized into three state-transition groups on the basis of an epidemiological cohort study. Yearly adherence transitions were incorporated into a Markov microsimulation using Tree Age software. Tracker variables were used to store adherence transitions, which were used to adjust probabilities of CV events over the patient's lifetime. Microsimulation loops “random walks” estimated the average accrued quality-adjusted life-years (QALYs) and CV events. For each 1,000-patient microsimulations, 10,000 outer loops were performed to reflect second-order uncertainty. Results: The adherence naive model estimated 0.14 CV events avoided per person, whereas the dynamic adherence model estimated 0.08 CV events avoided per person. Using the adherence-naive model, we found that statin therapy resulted in 0.40 QALYs gained over the lifetime horizon on average per person while the dynamic adherence model estimated 0.22 incremental QALYs gained. Subgroup analysis revealed that maintaining high adherence in year 2 resulted in 0.23 incremental QALYs gained as compared with 0.16 incremental QALYs gained when adherence dropped to the lowest level. Conclusions: A dynamic adherence Markov microsimulation model reveals risk reduction and effectiveness that are lower than with an adherence-naive model, and reflective of real-world practice. Such a model may highlight the value of improving or maintaining good adherence.",2014-09,21/11/2018 10:58,14/04/2020 08:34,,725-731,,6,17,,,,,,,,,,,,,,,,,,,,,1; Markov; 310,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BFP4R6AF,journalArticle,2014,"Matta, Andrea; Chahed, Salma; Sahin, Evren; Dallery, Yves",Modelling home care organisations from an operations management perspective,FLEXIBLE SERVICES AND MANUFACTURING JOURNAL,,1936-6582,10.1007/s10696-012-9157-0,,"Home Care (HC) service consists of providing care to patients in their homes. During the last decade, the HC service industry experienced significant growth in many European countries. This growth stems from several factors, such as governmental pressure to reduce healthcare costs, demographic changes related to population ageing, social changes, an increase in the number of patients that suffer from chronic illnesses, and the development of new home-based services and technologies. This study proposes a framework that will enable HC service providers to better understand HC operations and their management. The study identifies the main processes and decisions that relate to the field of HC operations management. Hence, an IDEF0 (Integrated Definition for Function Modelling) activity-based model describes the most relevant clinical, logistical and organisational processes associated with HC operations. A hierarchical framework for operations management decisions is also proposed. This analysis is derived from data that was collected by nine HC service providers, which are located in France and Italy, and focuses on the manner in which operations are run, as well as associated constraints, inputs and outputs. The most challenging research areas in the field of HC operations management are also discussed.",2014-09,21/11/2018 10:58,14/04/2020 08:34,,295-319,,3,26,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8JRZP574,journalArticle,2014,"Flentje, M.; Schott, M.; Pfuetzner, A.; Jantzen, J. -P.",Establishment of a multidisciplinary simulation-based delivery room team training with the object to improve patient safety,NOTFALL & RETTUNGSMEDIZIN,,1434-6222,10.1007/s10049-013-1799-2,,"An emergency C-section is a classic emergency situation that requires immediate and perfect cooperation. Simulation-based trainings are already part of the education of health care professionals in the U.K. to prevent serious adverse events in patient care (and used for the training of all those involved). A simulator-based team training for the delivery room has been established as part of the integrated approach to patient safety at KRH Klinikum Hannover Nord. The 4-h course concept includes a theoretical introduction and four simulation scenarios. After each simulation, a detailed debriefing is conducted by the coaches. Learning objectives are the improvement of the personal attitude towards safe performance of an emergency C-section in common peripartum emergencies (eclampsia, uterine rupture, placenta previa, and umbilical cord abnormalities) and the communication between all parties involved. The participants of the course also gain basic knowledge of incident management and are introduced to a concept for a debriefing of serious adverse events. The evaluation of our team training shows a very high acceptance and a great studying effect among the professional groups involved. All participants rated the training as “important” to “extremely important” for their clinical work. Even experienced employees are inspired by the simulation-based emergency training and benefit from the introduction to the incident management concept. These results underline the significance of team training for patient safety. The implementation of this training is crucial for the long-term benefit of our program and, therefore, needs to be an essential part of clinical routine. Our goal is to examine the impact of team training and monitor changes in performance in order to justify the resource allocations.",2014-08,21/11/2018 10:58,14/04/2020 08:34,,379-385,,5,17,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Y8DMJZ7C,journalArticle,2014,"Bhaludin, Basrull Najmi; Shelmerdine, Susan Cheng; Arora, Sonal; Senbanjo, Taiwo; Parthipun, Arum",Delays and errors in abnormal chest radiograph follow-up: a systems approach to promoting patient safety in radiology,JOURNAL OF EVALUATION IN CLINICAL PRACTICE,,1356-1294,10.1111/jep.12178,,"Rationale, aims and objectives This study aimed to apply the `systems approach' to patient safety in order to identify causes for delays and errors in lung cancer diagnoses following an abnormal chest radiograph. Methods In the first part of this study, the systems approach to patient safety was comprehensively reviewed by three radiologists and seven patient safety experts. In the second part of this study, a retrospective review was performed of all patients referred to the lung cancer multidisciplinary team (MDT) meeting over a 1-year period. All abnormal chest radiograph reports were examined and a root-cause analysis performed of cases where errors and delays in diagnoses were deemed to have occurred. Results A total of 124 cases were reviewed, of which 36 (29%) patients had an abnormal preceding chest radiograph prior to MDT referral. In six cases, serious errors from delay and lack of follow-up were identified. These are analysed and discussed in detail in this article. Application of the systems approach to each case identified poor communication and lack of clinical action as prime causes. Conclusions Both reporting radiologists and referring clinicians have a responsibility to ensure appropriate action following an abnormal chest radiograph. The main error lies in communication between the referring clinicians and the radiologists. Direct electronic communication is potentially a more robust method to overcome this.",2014-08,21/11/2018 10:58,14/04/2020 08:34,,453-459,,4,20,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NQRD62D8,journalArticle,2014,"Chiem, Jean-Christophe; Van Durme, Therese; Vandendorpe, Florence; Schmitz, Olivier; Speybroeck, Niko; Ces, Sophie; Macq, Jean",Expert knowledge elicitation using computer simulation: the organization of frail elderly case management as an illustration,JOURNAL OF EVALUATION IN CLINICAL PRACTICE,,1356-1294,10.1111/jep.12101,,"Background Various elderly case management projects have been implemented in Belgium. This type of long-term health care intervention involves contextual factors and human interactions. These underlying complex mechanisms can be usefully informed with field experts' knowledge, which are hard to make explicit. However, computer simulation has been suggested as one possible method of overcoming the difficulty of articulating such elicited qualitative views. Methods A simulation model of case management was designed using an agent-based methodology, based on the initial qualitative research material. Variables and rules of interaction were formulated into a simple conceptual framework. This model has been implemented and was used as a support for a structured discussion with experts in case management. Results The rigorous formulation provided by the agent-based methodology clarified the descriptions of the interventions and the problems encountered regarding: 1 the diverse network topologies of health care actors in the project; 2 the adaptation time required by the intervention; 3 the communication between the health care actors; 4 the institutional context; 5 the organization of the care; and 6 the role of the case manager and his or hers personal ability to interpret the informal demands of the frail older person. Conclusion The simulation model should be seen primarily as a tool for thinking and learning. A number of insights were gained as part of a valuable cognitive process. Computer simulation supporting field experts' elicitation can lead to better-informed decisions in the organization of complex health care interventions.",2014-08,21/11/2018 10:58,14/04/2020 08:34,,534-543,,4,20,,,,,,,,,,,,,,,,,,,,,"Humans; Professional Role; Aged; *Computer Simulation; Models, Organizational; Professional Competence; complexity; computer simulation; 00; *Expert Systems; *Frail Elderly; agent-based modelling; case management; Case Management/*organization & administration; Geriatric Nursing/*organization & administration; health care organization; knowledge; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VQJZJJ73,journalArticle,2014,"Zarca, K.; Durand-Zaleski, I.; Roux, C.; Souberbielle, J-C.; Schott, A-M.; Thomas, T.; Fardellone, P.; Benhamou, C-L.",Cost-effectiveness analysis of hip fracture prevention with vitamin D supplementation: a Markov micro-simulation model applied to the French population over 65 years old without previous hip fracture,OSTEOPOROSIS INTERNATIONAL,,0937-941X,10.1007/s00198-014-2698-1,,"We performed a cost-effectiveness analysis of four vitamin D supplementation strategies for primary prevention of hip fracture among the elderly population and found that the most cost-effective strategy was screening for vitamin D insufficiency followed by adequate treatment to attain a minimum 25(OH) serum level. Vitamin D supplementation has a demonstrated ability to reduce the incidence of hip fractures. The efficiency of lifetime supplementation has not yet been assessed in the population over 65 years without previous hip fracture. The objective was to analyze the efficiency of various vitamin D supplementation strategies for that population. A Markov micro-simulation model was built with data extracted from published studies and from the French reimbursement schedule. Four vitamin D supplementation strategies were evaluated on our study population: (1) no treatment, (2) supplementation without any serum level check; (3) supplementation with a serum level check 3 months after initiation and subsequent treatment adaptation; (4) population screening for vitamin D insufficiency followed by treatment based on the vitamin D serum level. “Treat, then check” and “screen and treat” were two cost-effective strategies and dominated “treat without check” with incremental cost-effectiveness ratios of a,not sign5,219/quality-adjusted life-years (QALY) and a,not sign9,104/QALY, respectively. The acceptability curves showed that over a,not sign6,000/QALY, the “screen and treat” strategy had the greatest probability of being cost-effective, and the “no treatment” strategy would never be cost-effective if society were willing to spend over a,not sign8,000/QALY. The sensitivity analysis showed that among all parameters varying within realistic ranges, the cost of vitamin D treatment had the greatest effect and yet remained below the WHO cost-effectiveness thresholds. Population screening for vitamin D insufficiency followed by treatment based on the vitamin D serum level is the most cost-effective strategy for preventing hip fracture occurrence in the population over 65 years old.",2014-06,21/11/2018 10:58,14/04/2020 08:35,,1797-1806,,6,25,,,,,,,,,,,,,,,,,,,,,1; Markov; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6RJEDYRA,journalArticle,2014,"Holloway, Ian W.; Rice, Eric; Kipke, Michele D.","Venue-Based Network Analysis to Inform HIV Prevention Efforts Among Young Gay, Bisexual, and Other Men Who Have Sex With Men",PREVENTION SCIENCE,,1389-4986,10.1007/s11121-014-0462-6,,"In the USA, human immunodeficiency virus (HIV) incidence rates continue to increase among young gay, bisexual, and other men have sexual intercourse with men. Young men who have sex with men (YMSM) indicate interest in HIV prevention programming that is implemented in the social venues that they frequent when they want to socialize with other men. We sought to understand YMSM venues as a networked space to provide insights into venue-based HIV prevention intervention delivery. The present study used survey data reported by 526 YMSM (ages 18-24) in 2005 to conduct a venue-based social network analysis. The latter sought to determine if the structure and composition of the networks in Los Angeles could be used to facilitate the delivery of HIV prevention messages to YMSM. Degree of person sharing between venues was used to demonstrate interconnectivity between venues classified as low risk (e.g., coffee shops) and high risk (e.g., bars and clubs) by a Community Advisory Board. Sixty-five percent of the 110 venues nominated were bars and clubs. Nearly all YMSM were connected by a single venue and over 87 % were connected by the six most central venues. A handful of highly connected low-risk venues was central to the venue network and connected to popular high-risk venues. Venue-based network analysis can inform tailored HIV prevention messaging for YMSM. Targeted delivery of prevention messaging at low-risk centralized venues may lead to widespread diffusion among venue-attending YMSM.",2014-06,21/11/2018 10:58,14/04/2020 08:34,,419-427,,3,15,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TXAY36D9,journalArticle,2014,"Gainforth, Heather L.; Latimer-Cheung, Amy E.; Athanasopoulos, Peter; Moore, Spencer; Ginis, Kathleen A. Martin",The role of interpersonal communication in the process of knowledge mobilization within a community-based organization: a network analysis,IMPLEMENTATION SCIENCE,,1748-5908,10.1186/1748-5908-9-59,,"Background: Diffusion of innovations theory has been widely used to explain knowledge mobilization of research findings. This theory posits that individuals who are more interpersonally connected within an organization may be more likely to adopt an innovation (e.g., research evidence) than individuals who are less interconnected. Research examining this tenet of diffusion of innovations theory in the knowledge mobilization literature is limited. The purpose of the present study was to use network analysis to examine the role of interpersonal communication in the adoption and mobilization of the physical activity guidelines for people with spinal cord injury (SCI) among staff in a community-based organization (CBO). Methods: The study used a cross-sectional, whole-network design. In total, 56 staff completed the network survey. Adoption of the guidelines was assessed using Rogers' innovation-decision process and interpersonal communication was assessed using an online network instrument. Results: The patterns of densities observed within the network were indicative of a core-periphery structure revealing that interpersonal communication was greater within the core than between the core and periphery and within the periphery. Membership in the core, as opposed to membership in the periphery, was associated with greater knowledge of the evidence-based physical activity resources available and engagement in physical activity promotion behaviours (ps<0.05). Greater in-degree centrality was associated with adoption of evidence-based behaviours (p<0.05). Conclusions: Findings suggest that interpersonal communication is associated with knowledge mobilization and highlight how the network structure could be improved for further dissemination efforts.",22/05/2014,21/11/2018 10:58,14/04/2020 08:34,,,,,9,,,,,,,,,,,,,,,,,,,,,110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, SCA2MVVH,journalArticle,2014,"Ansah, John P.; Eberlein, Robert L.; Love, Sean R.; Bautista, Mary Ann; Thompson, James P.; Malhotra, Rahul; Matchar, David B.",Implications of long-term care capacity response policies for an aging population: A simulation analysis,HEALTH POLICY,,0168-8510,10.1016/j.healthpol.2014.01.006,,"Introduction: The demand for long-term care (LTC) services is likely to increase as a population ages. Keeping pace with rising demand for LTC poses a key challenge for health systems and policymakers, who may be slow to scale up capacity. Given that Singapore is likely to face increasing demand for both acute and LTC services, this paper examines the dynamic impact of different LTC capacity response policies, which differ in the amount of time over which LTC capacity is increased, on acute care utilization and the demand for LTC and acute care professionals. Methods: The modeling methodology of System Dynamics (SD) was applied to create a simplified, aggregate, computer simulation model for policy exploration. This model stimulates the interaction between persons with LTC needs (i.e., elderly individuals aged 65 years and older who have functional limitations that require human assistance) and the capacity of the healthcare system (i.e., acute and LTC services, including community-based and institutional care) to provide care. Because the model is intended for policy exploration, stylized numbers were used as model inputs. To discern policy effects, the model was initialized in a steady state. The steady state was disturbed by doubling the number of people needing LTC over the 30-year simulation time. Under this demand change scenario, the effects of various LTC capacity response policies were studied and sensitivity analyses were performed. Results: Compared to proactive and quick adjustment LTC capacity response policies, slower adjustment LTC capacity response policies (i.e., those for which the time to change LTC capacity is longer) tend to shift care demands to the acute care sector and increase total care needs. Conclusions: Greater attention to demand in the acute care sector relative to demand for LTC may result in over-building acute care facilities and filling them with individuals whose needs are better suited for LTC. Policymakers must be equally proactive in expanding LTC capacity, lest unsustainable acute care utilization and significant deficits in the number of healthcare professionals arise. Delaying LTC expansion could, for example, lead to increased healthcare expenditure and longer wait lists for LTC and acute care patients. (C) 2014 Elsevier Ireland Ltd. All rights reserved.",2014-05,21/11/2018 10:58,14/04/2020 08:34,,105-113,,1,116,,,,,,,,,,,,,,,,,,,,,"*Health Policy; Humans; Aged; Models, Statistical; Policy; System dynamics; Aging; Simulation; Age Factors; 1; Singapore; Singapore/epidemiology; *Long-Term Care/organization & administration/statistics & numerical data; Capacity Building/*organization & administration; Health Services Needs and Demand/statistics & numerical data; Long-term care; 310",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DNV7TJET,journalArticle,2014,"Kothari, Anita; Hamel, Nadia; MacDonald, Jo-Anne; Meyer, Mechthild; Cohen, Benita; Bonnenfant, Dorothy",Exploring Community Collaborations: Social Network Analysis as a Reflective Tool for Public Health,SYSTEMIC PRACTICE AND ACTION RESEARCH,,1094-429X,10.1007/s11213-012-9271-7,,"Social network analysis is a potentially useful reflective tool that could be used by public health practitioners to assess the overall composition of their networks, strengthen collaborations with other community partners, and evaluate network function. The purpose of this paper is to report on public health practitioners' experiences with social network analysis. Thirteen public health practitioners, each associated with their own advocacy-oriented community collaboration, participated in the study. Specifically, the intervention consisted of social network analysis output (social network analysis measures and sociograms) and a facilitated discussion to stimulate reflection on the respondents' professional networks. Semi-structured interviews were conducted two weeks later to solicit participants' reactions to the sociograms and the accompanying measures, and elicit thoughts about how social network analysis might have an impact on their work. Participants commented on ways in which social network analysis could be applied in practice, such as using sociograms to raise awareness of the nature of current networks, as a planning and evaluation tool, to identify gaps, and to assess the degree of sustainability of current networks.",2014-04,21/11/2018 10:58,14/04/2020 08:34,,123-137,,2,27,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BBNPLRQI,journalArticle,2014,"Kadri, Farid; Chaabane, Sondes; Tahon, Christian",A simulation-based decision support system to prevent and predict strain situations in emergency department systems,SIMULATION MODELLING PRACTICE AND THEORY,,1569-190X,10.1016/j.simpat.2013.12.004,,"The management of patient flow, especially the flow resulting from health crises in emergency departments (ED), is one of the most important problems managed by ED managers. To handle this influx of patients, emergency departments require significant human and material resources, but these are limited. Under these conditions, the medical and paramedical staff are often confronted with strain situations. To deal with these situations, emergency departments have no choice but to adapt. The main purpose of this article is to develop a simulation-based decision support system (DSS) to prevent and predict strain situations in an ED in order to improve their management by the hospital system. A discrete-event simulation model was constructed in order to visualize the strain situations, examine the relationship between the strain situations and propose corrective actions. A simulation experiment is presented with the results, identifying several important aspects of the strain situations and corrective actions in ED systems. The results have proven the importance of anticipation and management of strain situations in emergency departments. (C) 2013 Elsevier B.V. All rights reserved.",2014-03,21/11/2018 10:58,14/04/2020 08:34,,32-52,,SI,42,,,,,,,,,,,,,,,,,,,,,1; Discrete event; 320,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JCMD38XF,journalArticle,2014,"Sokolowski, John A.; Banks, Catherine M.; Hakim, Paul",Simulation training to improve blood management: an approach to globalizing instruction in patient safety,SIMULATION-TRANSACTIONS OF THE SOCIETY FOR MODELING AND SIMULATION INTERNATIONAL,,0037-5497,10.1177/0037549712451786,,"In keeping with intent of this special issue-innovative ways to use modeling and simulation as an enabling technology-this paper addresses a global call for change in medical practice due to shifting populations, rising health risks, and increased expectation of governments to ensure patient safety. In advanced countries the basic economics of supply and demand are making a therapeutic commodity-blood-a costly treatment. In advancing states the rapid deformation of stored red blood cells and the prevalence of patient infection make standard transfusion medicine hazardous. As a result the World Health Organization has issued a call for alternatives to transfusion practice within the medical community. This paper introduces the implementation of patient blood management as that alternative standard of care, and it outlines an effective means to educate medical professionals via a web-based immersive simulation training tool. This tool was developed from evidence-based medicine, engineering and mathematical modeling, and simulations drawn from patient case studies. The medical instruction comprising this tool and its portability can readily serve a global audience of practitioners who are unfamiliar with these techniques and who are without an expedient means to obtain training. The tool is a multidisciplinary effort drawing on engineering, computer science, social science, and medical expertise. And just as this special issue stresses that simulation represents probably the only methodology to provide the human race with a tool for enabling control of mankind's evolution. Representing the cornerstone for anticipating future critical situations, this tool responds to an imminent dilemma in the global medical community.",2014-02,21/11/2018 10:58,14/04/2020 08:35,,133-142,,"2, SI",90,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FM2H3GNB,journalArticle,2014,"Cori, Anne; Ayles, Helen; Beyers, Nulda; Schaap, Ab; Floyd, Sian; Sabapathy, Kalpana; Eaton, Jeffrey W.; Hauck, Katharina; Smith, Peter; Griffith, Sam; Moore, Ayana; Donnell, Deborah; Vermund, Sten H.; Fidler, Sarah; Hayes, Richard; Fraser, Christophe; Team, HPTN 071 PopART Study",HPTN 071 (PopART): A Cluster-Randomized Trial of the Population Impact of an HIV Combination Prevention Intervention Including Universal Testing and Treatment: Mathematical Model,PLOS ONE,,1932-6203,10.1371/journal.pone.0084511,,"Background: The HPTN 052 trial confirmed that antiretroviral therapy (ART) can nearly eliminate HIV transmission from successfully treated HIV-infected individuals within couples. Here, we present the mathematical modeling used to inform the design and monitoring of a new trial aiming to test whether widespread provision of ART is feasible and can substantially reduce population-level HIV incidence. Methods and Findings: The HPTN 071 (PopART) trial is a three-arm cluster-randomized trial of 21 large population clusters in Zambia and South Africa, starting in 2013. A combination prevention package including home-based voluntary testing and counseling, and ART for HIV positive individuals, will be delivered in arms A and B, with ART offered universally in arm A and according to national guidelines in arm B. Arm C will be the control arm. The primary endpoint is the cumulative threeyear HIV incidence. We developed a mathematical model of heterosexual HIV transmission, informed by recent data on HIV-1 natural history. We focused on realistically modeling the intervention package. Parameters were calibrated to data previously collected in these communities and national surveillance data. We predict that, if targets are reached, HIV incidence over three years will drop by.60% in arm A and.25% in arm B, relative to arm C. The considerable uncertainty in the predicted reduction in incidence justifies the need for a trial. The main drivers of this uncertainty are possible community-level behavioral changes associated with the intervention, uptake of testing and treatment, as well as ART retention and adherence. Conclusions: The HPTN 071 (PopART) trial intervention could reduce HIV population-level incidence by.60% over three years. This intervention could serve as a paradigm for national or supra-national implementation. Our analysis highlights the role mathematical modeling can play in trial development and monitoring, and more widely in evaluating the impact of treatment as prevention.",15/01/2014,21/11/2018 10:58,14/04/2020 08:34,,,,1,9,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2MCU8KLZ,conferencePaper,2014,"Ali, Mahmood; Cullinane, Joanna",A study to evaluate the effectiveness of simulation based decision support system in ERP implementation in SMEs,CENTERIS 2014 - CONFERENCE ON ENTERPRISE INFORMATION SYSTEMS / PROJMAN 2014 - INTERNATIONAL CONFERENCE ON PROJECT MANAGEMENT / HCIST 2014 - INTERNATIONAL CONFERENCE ON HEALTH AND SOCIAL CARE INFORMATION SYSTEMS AND TECHNOLOGIES,,,10.1016/j.protcy.2014.10.002,,"ERP system implementation is a challenging process and small medium enterprises (SMEs) face considerable challenges in implementing ERP system due to their limited resources and IT infrastructure. Still, due to their benefits, ERP systems are becoming an integral part of SMEs. This study evaluates the role simulation based modelling can play in assisting SMEs in ERP implementation. The key informants representing diverse backgrounds are interviewed to collected data. The findings of the research show that Key participants supported the idea of incorporating simulation based model during the implementation process since a simulation based approach make more sense since it will allow the implementation team to observe the implementation process and the role played by factors which are essential for the success of the implementation. Also, simulation model can also be useful in developing and analyzing different implementation strategies, predict efforts and resources needed for ERP implementation, which in turn can facilitate decision makers in adopting a ERP system or not. (C) 2014 The Authors. Published by Elsevier Ltd.",2014,21/11/2018 10:59,14/04/2020 08:34,,542-552,,,16,,,,Procedia Technology,,,,,,,,,,,,,,"

Conference on ENTERprise Information Systems (CENTERIS) / International Conference on Project MANagement (ProjMAN) / International Conference on Health and Social Care Information Systems and Technologies (HCIST), Troia, PORTUGAL, OCT 15-17, 2014

",,,00; 110,,"Varajao, J and Cunha, M and BjornAndersen, N and Turner, R and Wijesekera, D and Martinho, R and Rijo, R",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, U8CCYQUF,conferencePaper,2014,"Liu, Shan; Cipriano, Lauren E.; Goldhaber-Fiebert, Jeremy D.",Extended Abstract: Combining Statistical Analysis and Markov Models with Public Health Data to Infer Age-Specific Background Mortality Rates for Hepatitis C Infection in the US,"SMART HEALTH, ICSH 2014",978-3-319-08416-9 978-3-319-08415-2,,,,"Chronic hepatitis C (HCV) is a significant public health problem affecting 2.7-3.9 million Americans. Quantifying mortality rates of HCV-infected individuals permits more accurate estimates of the potential benefits of HCV screening and treatment. With 5% of older Americans infected with HCV, cost-effectiveness analyses of expanded HCV screening and treatment require methods to appropriately quantify differential mortality risks. No single study contains data needed to estimate subgroup-specific prevalence of HCV, risk factor status, and mortality risks. We developed a combined modeling approach to infer risk-group-specific mortality rates for chronically HCV-infected U.S. adults. We incorporated estimates from public health data into a Markov model to infer the age-, sex-, race-, risk-, and HCV infection status-specific mortality rates that best fit the overall age-specific population mortality rates.",2014,21/11/2018 10:59,14/04/2020 08:34,,148+,,,8549,,,,Lecture Notes in Computer Science,,,,Tsinghua Univ; Chinese Acad Sci; Natl Nat Sci Fdn China; Univ Arizona; Inst Operat Res & Management Sci; ACM Beijing Chapter; China Assoc Informat Syst,,,,,,,,,,"

International Conference for Smart Health (ICSH), Beijing, PEOPLES R CHINA, JUL 10-11, 2014

",,,1; Markov; 100,,"Zheng, X and Zeng, D and Chen, H and Zhang, Y and Xing, C and Neill, DB",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UKSPXQNA,journalArticle,2014,"Rasheed, Farrukh; Lee, Young Hoon",ENHANCING PERFORMANCE OF HEALTHCARE FACILITY VIA NOVEL SIMULATION METAMODELING BASED DECISION SUPPORT FRAMEWORK,INTERNATIONAL JOURNAL OF INDUSTRIAL ENGINEERING-THEORY APPLICATIONS AND PRACTICE,,1943-670X,,,"A simulation model of patient throughput in the community healthcare center (CHC) located in Seoul, Korea is developed. The aforementioned CHC is providing primary, secondary and tertiary healthcare (HC) services, i.e. diagnostic, illness, treatment, health screening, immunization, family planning, ambulatory care, pediatric and gynecologic along with various other support services to uninsured, under-insured and low income patients residing in the nearby medically underserved areas. The prime aim of this investigation is to identify main imperative variables via statistical analysis of de-identified customer tracking system dataset and based-on expert opinion. Afterwards, using proposed novel simulation metamodeling based decision support framework to gauge their impact on performance measures of interest. The identified independent variables are resource shortage and stochastic demand pattern while performance measures of interest are the average length of stay (LOSa), balking probability (P-b), reneging probability (P-r), overcrowding and resource utilization. Significance: The methodology presented in this research is unique in a sense: a single meta-model represents a single performance measure and the solution found may be sub-optimal, having a detrimental effect on other crucial performance measures of interest if not considered. Hence, it is emphasized to develop all possible meta-models representing all the crucial performance measures individually for the purpose of overcoming aforesaid draw back so that final solution may qualify itself as a real-optimal solution.",2014,21/11/2018 10:59,14/04/2020 08:34,,271-283,,5,21,,,,,,,,,,,,,,,,,,,,,simulation metamodeling; 1; 210,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ULWCKUSS,conferencePaper,2014,"Ma, Weina; Sartipi, Kamran",An Agent-based Infrastructure for Secure Medical Imaging System Integration,2014 IEEE 27TH INTERNATIONAL SYMPOSIUM ON COMPUTER-BASED MEDICAL SYSTEMS (CBMS),978-1-4799-4435-4,,10.1109/CBMS.2014.87,,"This research paper examines the weaknesses of the trusted models applied on the domain of medical image sharing between the PACS (Picturing Archiving and Communication System) and image-enabled EHR (Electronic Health Record) systems. In this paper, we propose implementing an agent-based infrastructure in the legacy PACS systems along a common infrastructure that we have proposed in our earlier work. The proposed architecture allows for capturing PACS communication messages; identifying users; extracting user actions to feed into an action-based access control mechanism; and integrating with modern authentication and authorization technologies (OpenID and OAuth). We also provide a UML model for the patient consent directives to allow for systematic enforcement of their impact on the proposed access control technique. Finally, we implemented a prototype of the proposed architecture using open source tools to demonstrate the feasibility and extendibility of our proposed solution.",2014,21/11/2018 10:59,14/04/2020 08:34,,72-77,,,,,,,IEEE International Symposium on Computer-Based Medical Systems,,,,IEEE; IEEE Comp Soc; Texas Tech Univ; IBMWATSON,,,,,,,,,,"

27th IEEE International Symposium on Computer-Based Medical Systems (CBMS), Icahn Sch Med, New York, NY, MAY 27-29, 2014

",,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8EF4RFIY,journalArticle,2014,"Olson, C. H.; Dierich, M.; Adam, T.; Westra, B. L.",Optimization of Decision Support Tool using Medication Regimens to Assess Rehospitalization Risks,APPLIED CLINICAL INFORMATICS,,1869-0327,10.4338/ACI-2014-04-RA-0040,,"Background: Unnecessary hospital readmissions are costly for the U.S. health care system. An automated algorithm was developed to target this problem and proven to predict elderly patients at greater risk of rehospitalization based on their medication regimens. Objective: Improve the algorithm for predicting elderly patients' risks for readmission by optimizing the sensitivity of its medication criteria. Methods: Outcome and Assessment Information Set (OASIS) and medication data were reused from a study that defined and tested an algorithm for assessing rehospitalization risks of 911 patients from 15 Medicare-certified home health care agencies. Odds Ratio analyses, literature reviews and clinical judgments were used to adjust the scoring of patients' High Risk Medication Regimens (HRMRs). Receiver Operating Characteristic (ROC) analysis evaluated whether these adjustments improved the predictive strength of the algorithm's components. Results: HRMR scores are composed of polypharmacy (number of drugs), potentially inappropriate medications (PIM) (drugs risky to the elderly), and Medication Regimen Complexity Index (MRCI) (complex dose forms, dose frequency, instructions or administration). Strongest ROC results for the HRMR components were Areas Under the Curve (AUC) of .68 for polypharmacy when excluding supplements; and .60 for PIM and .69 for MRCI using the original HRMR criteria. The “cut point” identifying MRCI scores as indicative of medication-related readmission risk was increased from 20 to 33. Conclusion: The automated algorithm can predict elderly patients at risk of hospital readmissions and its underlying criteria is improved by a modification to its polypharmacy definition and MRCI cut point.",2014,21/11/2018 10:59,14/04/2020 08:35,,773-788,,3,5,,,,,,,,,,,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, C9GJT87K,journalArticle,2014,"McCovery, Jarred; Matusitz, Jonathan",Assessment of Collaboration in US Health Care Delivery: A Perspective from Systems Theory,SOCIAL WORK IN PUBLIC HEALTH,,1937-1918,10.1080/19371918.2013.865109,,"This analysis applies the core principles of systems theory to health care delivery in the United States. Particularly examined is the role of collaboration between health care agencies/organizations in the United States. This includes cooperation and teamwork among health professionals (i.e., nurses, technicians, physicians, and laboratory staff). By and large, systems theory posits that (a) all singular units within a system are interconnected and (b) the whole is more than the sum of its parts. This analysis identifies areas within the U.S. public health system where it is essential to embody elements of cooperation and collaboration, not only to bolster physical and financial support, but also to ensure a substantial impact within the community.",2014,21/11/2018 10:59,14/04/2020 08:34,,451-461,,5,29,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PWZ2EWJQ,conferencePaper,2014,"Liu, Qiwei",Study on Mine Pneumoconiosis Disease Prevention and Control Based on Method of LEC and Markov Train,"ENVIRONMENTAL ENGINEERING, PTS 1-4",978-3-03785-973-5,,10.4028/www.scientific.net/AMR.864-867.775,,"Used the Markov Train model, a mining enterprises pneumoconiosis incidence trends is predicted. The result shows that the unit pneumoconiosis development quickly, must strengthen the dust prevention and control. Using LEC method to mine in the workplaces where harm worker healthy environments were evaluated and harm through improved LEC method for scientific management, and put forward effective countermeasures to control, for the prevention of occupational health hazards in mines and puts forward scientific basis for control.",2014,21/11/2018 10:59,14/04/2020 08:34,,775-781,,,864-867,,,,Advanced Materials Research,,,,Shanghai Univ Elect Power; Shanghai Normal Univ,,,,,,,,,,"

3rd International Conference on Energy, Environment and Sustainable Development (EESD 2013), Shanghai, PEOPLES R CHINA, NOV 12-13, 2013

",,,00; 100,,"Li, H and Xu, Q and Ge, H",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, C3M6DCDA,journalArticle,2014,"Cummings, Louise",Informal Fallacies as Cognitive Heuristics in Public Health Reasoning,INFORMAL LOGIC,,0824-2577,,,"The public must make assessments of a range of health-related issues. However, these assessments require scientific knowledge which is often lacking or ineffectively utilized by the public. Lay people must use whatever cognitive resources are at their disposal to come to judgement on these issues. It will be contended that a group of arguments-so-called informal fallacies- are a valuable cognitive resource in this regard. These arguments serve as cognitive heuristics which facilitate reasoning when knowledge is limited or beyond the grasp of reasoners. The results of an investigation into the use of these arguments by the public are reported.",2014,21/11/2018 10:59,14/04/2020 08:34,,Jan-37,,1,34,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, L3AI8GFU,conferencePaper,2014,"Gubara, Ashraf; Amasha, Ali; Ahmed, Zakaria; El Ghazali, Shawki",DECISION SUPPORT SYSTEM NETWORK ANALYSIS FOR EMERGENCY APPLICATIONS,2014 9th International Conference on Informatics and Systems (INFOS),978-977-403-689-7,,,,"Preparedness is the main criteria for immediate response for any emergency response provider (ERP) and decision support system. Emergency Response System can be either for fire emergency response system, or police station emergency response system and healthcare emergency response system. Emergency decision support system is imperative for the reduction of disaster losses and the efficiency improvement of emergency resources allocation. The objective of this paper is to establish a Geographic Information System (GIS) based healthcare emergency response system for services that can identify the optimal route from the location of incident to any healthcare service providers, and the optimal route was modeled based on the distance (the shortest path) to the closest healthcare service providers. Therefore, the main outcome from this research is to provide immediate response to any request for incidents or accidents. Basic idea behind developing this web application is that a case (patient) or incident occurs at a particular location (latitude and longitude). Knowing those locations and mapping them using (GIS) would greatly help in analyzing and visualizing the various factors associated with the incident and thus would help in providing better decision making and quicker response for any incident or accident using ArcGIS Server and web application. The rest of the paper is organized as follows: Section 2 describes the aims and objective of the research, Section 3 discusses the methodology which includes the description of the study area, data inputs and healthcare emergency response model parameters. In section 4, analyses including shortest path, spatial queries and also service area for healthcare providers are displayed. Results are presented and interpretation is illustrated in Section 4. Conclusions and discussions of future research works are outlined in Section 5",2014,21/11/2018 10:59,14/04/2020 08:34,,,,,,,,,,,,,IEEE,,,,,,,,,,"

9th International Conference on Informatics and Systems, Cairo, EGYPT, DEC 15-17, 2014

",,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, B2JQF5C5,conferencePaper,2014,"Sernani, Paolo; Claudi, Andrea; Dragoni, AldoFranco",A Multi-Agent Expert System Simulation for Ambient Assisted Living: The Virtual Carer Experience,AMBIENT ASSISTED LIVING,978-3-319-01119-6 978-3-319-01118-9,,10.1007/978-3-319-01119-6_9,,"A shift in the distribution of population towards older ages is occurring in almost every country of the world and it is becoming a major problem in Europe, Japan and USA, due to the high dependency ratio of these countries. Ambient Assisted Living (AAL) and Ambient Intelligence (AmI) are polarising the attention of the research community, trying to improve the quality of life of elderly people promoting their autonomy, self-confidence and mobility. Artificial Intelligence (AI), developing intelligent and adaptable systems, can play a considerable role in AAL and AmI to cope with the changing needs that characterize the life of people with chronic diseases. To show a possible contribution of AI in these fields, this paper introduces the multi-agent architecture of an expert system for Ambient Assisted Living: the Virtual Carer (VC). Based on the Belief-Desire-Intention (BDI) paradigm, it models the behaviours of a human caregiver. The main goal of the Virtual Carer is to help an elderly patient in his daily activities, while his health conditions are monitored, in order to ensure his security. To show the main capabilities of the system, the paper describes some simulations of the proposed agency, highlighting the architecture of the reasoning component.",2014,21/11/2018 10:59,14/04/2020 08:35,,87-96,,,,,,,,,,,,,,,,,,,,,"

4th Italian Forum on Ambient Assisted Living (AAL), Ancona, ITALY, OCT, 2013

",,,00; 110,,"Longhi, S and Siciliano, P and Germani, M and Monteriu, A",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, C3SRSBHY,journalArticle,2013,"Saha, Sanjib; Carlsson, Katarina Steen; Gerdtham, Ulf-G; Eriksson, Margareta K.; Hagberg, Lars; Eliasson, Mats; Johansson, Pia","Are Lifestyle Interventions in Primary Care Cost-Effective? - An Analysis Based on a Markov Model, Differences-In-Differences Approach and the Swedish Bjorknas Study",PLOS ONE,,1932-6203,10.1371/journal.pone.0080672,,"Background: Lifestyle interventions affect patients' risk factors for metabolic syndrome (MeSy), a pre-stage to cardiovascular diseases, diabetes and related complications. An effective lifestyle intervention is the Swedish Bjorknas intervention, a 3-year randomized controlled trial in primary care for MeSy patients. To include future disease-related cost and health consequences in a cost-effectiveness analysis, a simulation model was used to estimate the short-term (3-year) and long-term (lifelong) cost-effectiveness of the Bjorknas study. Methodology/Principal Findings: A Markov micro-simulation model was used to predict the cost and quality-adjusted life years (QALYs) for MeSy-related diseases based on ten risk factors. Model inputs were levels of individual risk factors at baseline and at the third year. The model estimated short-term and long-term costs and QALYs for the intervention and control groups. The cost-effectiveness of the intervention was assessed using differences-in-differences approach to compare the changes between the groups in the health care and societal perspectives, using a 3% discount rate. A 95% confidence interval (CI), based on bootstrapping, and sensitivity analyses describe the uncertainty in the estimates. In the short-term, costs are predicted to increase over time in both groups, but less in the intervention group, resulting in an average cost saving/reduction of US$-700 (in 2012, US $ 1= six point five seven SEK) and US$-500, in the societal and health care perspectives. The long-term estimate also predicts increased costs, but considerably less in the intervention group: US$-7,300 (95% CI: US$-19,700 to US $-1,000) in the societal, and US$-1,500 (95% CI: US$-5,400 to US$ 2,650) in the health care perspective. As intervention costs were US$ 211 per participant, the intervention would result in cost saving. Furthermore, in the long-term an estimated 0.46 QALYs (95% CI: 0.12 to 0.69) per participant would be gained. Conclusions/Significance: The Swedish Bjorknas study appears to reduce demands on societal and health care resources and increase health-related quality of life.",14/11/2013,21/11/2018 10:59,14/04/2020 08:34,,,,11,8,,,,,,,,,,,,,,,,,,,,,Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Female; Male; Middle Aged; Markov Chains; Risk Reduction Behavior; *Life Style; 1; Primary Health Care/*economics/*methods; Markov; 410,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QFF7VSRU,journalArticle,2013,"Odukoya, Olufunmilola K.; Chui, Michelle A.",e-Prescribing: characterisation of patient safety hazards in community pharmacies using a sociotechnical systems approach,BMJ QUALITY & SAFETY,,2044-5415,10.1136/bmjqs-2013-001834,,"Objective To characterise the safety hazards related to e-prescribing in community pharmacies. Methods The sociotechnical systems framework was used to investigate the e-prescribing technology interface in community pharmacies by taking into consideration the social, technical and environmental work elements of a user's interaction with technology. This study focused specifically on aspects of the social subsystem. Study design and setting The study employed a cross-sectional qualitative design and was conducted in seven community pharmacies in Wisconsin. Direct observations, think aloud protocols and group interviews were conducted with 14 pharmacists and 16 technicians, and audio recorded. Recordings were transcribed and subjected to thematic content analysis guided by the sociotechnical systems' theoretical framework. Results Three major themes that may increase the potential for medication errors with e-prescribing were identified and described. The three themes included: (1) increased cognitive burden on pharmacy staff, such as having to memorise parts of e-prescriptions or having to perform dosage calculations mentally; (2) interruptions during the e-prescription dispensing process; and (3) communication issues with prescribers, patients and among pharmacy staff. Pharmacy staff reported these consequences of e-prescribing increased the likelihood of medication errors. Conclusions This study is the first of its kind to identify patient safety risks related to e-prescribing in community pharmacies using a sociotechnical systems framework. The findings shed light on potential interventions that may enhance patient safety in pharmacies and facilitate improved e-prescribing use. Future studies should confirm patient safety hazards reported and identify ways to use e-prescribing effectively and safely in community pharmacies.",2013-10,21/11/2018 10:59,14/04/2020 08:35,,816-825,,10,22,,,,,,,,,,,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XNDLLLVF,journalArticle,2013,"Dorjee, S.; Revie, C. W.; Poljak, Z.; McNab, W. B.; Sanchez, J.","Network analysis of swine shipments in Ontario, Canada, to support disease spread modelling and risk-based disease management",PREVENTIVE VETERINARY MEDICINE,,0167-5877,10.1016/j.prevetmed.2013.06.008,,"Understanding contact networks are important for modelling and managing the spread and control of communicable diseases in populations. This study characterizes the swine shipment network of a multi-site production system in southwestern Ontario, Canada. Data were extracted from a company's database listing swine shipments among 251 swine farms, including 20 sow, 69 nursery and 162 finishing farms, for the 2-year period of 2006 to 2007. Several network metrics were generated. The number of shipments per week between pairs of farms ranged from 1 to 6. The medians (and ranges) of out-degree were: sow 6 (1-21), nursery 8(0-25), and finishing 0(0-4), over the entire 2-year study period. Corresponding estimates for in-degree of nursery and finishing farms were 3 (0-9) and 3 (0-12) respectively. Outgoing and incoming infection chains (OIC and IIC), were also measured. The medians (ranges) of the monthly OIC and IIC were 0 (0-8) and 0 (0-6), respectively, with very similar measures observed for 2-week intervals. Nursery farms exhibited high measures of centrality. This indicates that they pose greater risks of disease spread in the network. Therefore, they should be given a high priority for disease prevention and control measures affecting all age groups alike. The network demonstrated scale-free and small-world topologies as observed in other livestock shipment studies. This heterogeneity in contacts among farm types and network topologies should be incorporated in simulation models to improve their validity. In conclusion, this study provided useful epidemiological information and parameters for the control and modelling of disease spread among swine farms, for the first time from Ontario, Canada. (C) 2013 Elsevier B.V. All rights reserved.",01/10/2013,21/11/2018 10:59,14/04/2020 08:34,,118-127,,01-Feb,112,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NTQMHXZI,journalArticle,2013,"Churilov, Leonid; Fridriksdottir, Audur; Keshtkaran, Mahsa; Mosley, Ian; Flitman, Andrew; Dewey, Helen M.",Decision support in pre-hospital stroke care operations: A case of using simulation to improve eligibility of acute stroke patients for thrombolysis treatment,COMPUTERS & OPERATIONS RESEARCH,,0305-0548,10.1016/j.cor.2012.06.012,,"Stroke is the third most common cause of death and the sixth most common cause of disability worldwide. Treating acute ischemic stroke with thrombolytic therapy within 4.5 hours from symptom onset is effective in improving patient outcomes. The time from stroke onset to arrival to hospital has been identified as the single most important issue in determining patients' eligibility for stroke thrombolysis. There is a need for simultaneous systemic evaluation of multi-factorial interventions in pre-hospital acute care systems, aimed at increasing patients' eligibility for stroke thrombolysis. In this paper an OR solution is proposed in the form of a simulation model that provides clear measure of the relative benefit of alternative potential interventions, demonstrating how OR modeling can be used for providing decision support in pre-hospital stroke care operations and contributing to health OR literature. (C) 2012 Elsevier Ltd. All rights reserved.",2013-09,21/11/2018 10:59,14/04/2020 08:34,,2208-2218,,"9, SI",40,,,,,,,,,,,,,,,,,,,,,Operations Research; 1; OR; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, U9BHN9ET,journalArticle,2013,"Bultas, Margaret W.; Curtis, Mary P.",Using Simulation to Teach Child Injury Prevention to Mothers Recovering from Substance Abuse,JOURNAL OF COMMUNITY HEALTH NURSING,,0737-0016,10.1080/07370016.2013.806720,,"A paucity of literature regarding strategies for injury prevention in children for mothers with substance abuse exists. Substance abuse propagates distractions such as inattention; therefore, these mothers should be targeted for injury prevention education. A quasi-experimental design compared the results of traditional classroom teaching with an innovative home hazard simulation activity to teach injury prevention to mothers recovering from substance abuse. Study results identified a need to employ multiple modalities when teaching injury prevention. Information obtained from this research suggests a need for continued study and adaptation of current teaching strategies for injury prevention education in other high-risk populations.",01/07/2013,21/11/2018 10:59,14/04/2020 08:34,,155-163,,3,30,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PFXUGU78,journalArticle,2013,"Benzarti, Emna; Sahin, Evren; Dallery, Yves",Operations management applied to home care services: Analysis of the districting problem,DECISION SUPPORT SYSTEMS,,0167-9236,10.1016/j.dss.2012.10.015,,"In this paper, we focus on a specific operations management related issue faced by home health care (HHC) services, namely the districting problem. Our contribution consists of formulating the HHC districting problem as a mixed-integer programming model by considering criteria such as the indivisibility of the basic units (i.e. locations where patients live), compactness, workload balance between human resources and compatibility. The formulations developed are based either on balancing the personnel care workload or minimizing the travel distance to reach the patients. Computational results obtained from the models show that they enable to improve the service quality towards HHC patients as well as caregivers by optimizing the compactness and workload balance criteria. (C) 2012 Elsevier B.V. All rights reserved.",2013-05,21/11/2018 10:59,14/04/2020 08:34,,587-598,,"2, SI",55,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RREIH7HR,conferencePaper,2013,"Rasmussen, Stine Loft; Jensen, Sanne; Lyng, Karen Marie",Clinical simulation as a boundary object in design of health IT-systems,CONTEXT SENSITIVE HEALTH INFORMATICS: HUMAN AND SOCIOTECHNICAL APPROACHES,978-1-61499-293-6 978-1-61499-292-9,,10.3233/978-1-61499-293-6-173,,"Healthcare organizations are very complex, holding numerous stakeholders with various approaches and goals towards the design of health IT-systems. Some of these differences may be approached by applying the concept of boundary objects in a participatory IT-design process. Traditionally clinical simulation provides the opportunity to evaluate the design and the usage of clinical IT-systems without endangering the patients and interrupting clinical work. In this paper we present how clinical simulation additionally holds the potential to function as a boundary object in the design process. The case points out that clinical simulation provides an opportunity for discussions and mutual learning among the various stakeholders involved in design of standardized electronic clinical documentation templates. The paper presents and discusses the use of clinical simulation in the translation, transfer and transformation of knowledge between various stakeholders in a large healthcare organization.",2013,21/11/2018 10:59,14/04/2020 08:35,,173-178,,,194,,,,Studies in Health Technology and Informatics,,,,IMIA Working Grp Human Factors Engn Healthcare Informat Org & Social Issues; Hlth Informat Patient Safety; EFMI WG Human & Org Factors Med Informat,,,,,,,,,,"

International Conference on Context Sensitive Health Informatics, Human and Sociotechnical Approaches, Herlev Hosp, Copenhagen, DENMARK, AUG, 2013

",,,00; 110,,"BeuscartZephir, MC and Jaspers, M and Kuziemsky, C and Nohr, C and Aarts, J",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NL4IB9IK,journalArticle,2013,"Brazeau, Randi H.; Edwards, Marc A.","OPTIMIZATION OF ELECTRIC HOT WATER RECIRCULATION SYSTEMS FOR COMFORT, ENERGY AND PUBLIC HEALTH",JOURNAL OF GREEN BUILDING,,1552-6100,10.3992/jgb.8.2.73,,"Hot water recirculation systems (RECIRC) are labeled green and are sometimes mandated in local plumbing codes. Previous work conducted under non-optimized operation schemes demonstrated that these systems actually waste energy and water versus standard (STAND) water heater counterparts. Optimization of RECIRC system operation by minimizing pump operation did improve energy efficiency 6-60%, saving consumers 5-140% annually in associated utility costs. However, STAND systems were still more energy efficient than any of the RECIRC systems. With respect to factors that might influence pathogen growth, reducing RECIRC pump operations increased disinfectant residual by as much as 560% as compared to the baseline RECIRC system; however, STAND systems still had 25-250% more total chlorine residual than any of the RECIRC systems. At 60 degrees C operating temperature, STAND systems have 30-230% more volume at risk for pathogen growth (e.g., volume with temp 37-46 degrees C) than any of the RECIRC systems. Thus, in the context of “green” design, RECIRC systems provide a convenience to consumers in the form of nearly instant hot water, at a cost of higher capital, operating and overall energy costs. RECIRC systems have distinct advantages in controlling pathogens via thermal disinfection but disadvantages in control via secondary disinfection residual.",2013,21/11/2018 10:59,14/04/2020 08:34,,73-89,,2,8,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, G7N5NZ6S,journalArticle,2013,"Ravitz, Alan D.; Sapirstein, Adam; Pham, Julius C.; Doyle, Peter A.",Systems Approach and Systems Engineering Applied to Health Care: Improving Patient Safety and Health Care Delivery,JOHNS HOPKINS APL TECHNICAL DIGEST,,0270-5214,,,"Despite the introduction of technology in medicine, challenges related to patient safety and quality health care delivery still abound. The economic and personal costs associated with these challenges are enormous. To address these challenges, APL, Johns Hopkins Medicine, and the Whiting School of Engineering's Systems Institute have teamed to couple systems engineering principles and best practices with clinical expertise to develop innovative approaches to the socio-technical dynamics involved in health care. This work focuses on understanding the interactions among people (clinicians, patients, families, and other stakeholders), processes (institutional, regulatory, professional ethics, etc.), and technology (medical devices and instrumentation) in the health care domain to formulate a systems approach to innovations that lead to improved patient outcomes. APL and Johns Hopkins Medicine are collaborating on improvements at the device level, specifically medication infusion pumps that represent significant patient safety challenges, as well as at the unit level in the intensive care unit.",2013,21/11/2018 10:59,14/04/2020 08:35,,354-365,,4,31,,,,,,,,,,,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9Y5CXUZ4,journalArticle,2013,"Lee, Eva K.; Pietz, Ferdinand; Benecke, Bernard; Mason, Jacquelyn; Burel, Greg",Advancing Public Health and Medical Preparedness with Operations Research,INTERFACES,,0092-2102,10.1287/inte.2013.0676,,"Planning for a catastrophe involving a disease outbreak with the potential for mass casualties is a significant challenge for emergency managers. Public health experts at the US Centers for Disease Control and Prevention (CDC) teamed with operations researchers to address important aspects of mass dispensing: medical supply distribution, locations of dispensing facilities, optimal facility staffing and resource allocation, routing of the population, and dispensing methods. Simulation-optimization technology was integrated into a decision support and data management suite, RealOpt (c), for tactical and strategic operational planning. RealOpt has enabled the CDC to provide modern tools that support dynamic planning for emergencies and that establish a knowledge data bank to provide feedback about the deployment of various techniques. The RealOpt suite now has a US user base of over 6,500 public health and emergency directors covering all states, plus many international users. RealOpt has been applied in hundreds of drills and dispensing events, including anthrax preparedness, and for seasonal flu and H1N1 vaccination events.",2013-02,21/11/2018 10:59,14/04/2020 08:34,,79-98,,"1, SI",43,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6SSZ8ZUN,journalArticle,2013,"Ademi, Zanfina; Liew, Danny; Hollingsworth, Bruce; Steg, Ph. Gabriel; Bhatt, Deepak L.; Reid, Christopher M.; Investigators, REACH Registry",Is It Cost-Effective To Increase Aspirin Use in Outpatient Settings for Primary or Secondary Prevention? Simulation Data from the REACH Registry Australian Cohort,CARDIOVASCULAR THERAPEUTICS,,1755-5914,10.1111/j.1755-5922.2011.00291.x,,"Aims: To describe aspirin use in primary and secondary prevention and to determine the incremental costs effectiveness ratio (ICER) per life year gain (LYG) of aspirin use among subjects with, or at high risk of atherothrombotic disease. Design and Subjects: To project the cost-effectiveness of aspirin over 5 years of follow-up, a Markov state transition model was developed with yearly cycles and the following health states: Alive (post-CAD) and Dead. The model compared current coverage observed among 2361 subjects using the prospective Australian subset of Reduction of Atherothrombosis for continued Health (REACH) registry, and hypothetical situation whereby all subjects assumed to be treated. Costs were calculated based on the Australian government reimbursed data for 2010. Main outcome measures: ICER per LYG for increased use of aspirin. Results: The use of aspirin in current group varied from 67% to 70%. The base-case analysis showed that increasing aspirin use among subjects with existing CAD in outpatient settings was cost saving, while increasing use of aspirin in primary prevention equated to an ICER of AUD 7126 per LYG. Conclusion: Among subjects with existing CAD aspirin use was shown to be a dominant choice of treatment. However, among patients without existing cardiovascular disease (primary prevention), increased uptake of aspirin was cost effective but with uncertain benefit, with two hemorrhagic bleeding events occurring for every life saved.",2013,21/11/2018 10:59,14/04/2020 08:34,,45-52,,1,31,,,,,,,,,,,,,,,,,,,,,"Humans; Cost-Benefit Analysis; Female; Male; Middle Aged; Aged; Markov Chains; *Computer Simulation; Aged, 80 and over; Uncertainty; Australia; Time Factors; Ambulatory Care/*economics; Models, Economic; Registries; *Drug Costs; Hemorrhage/chemically induced/economics; Aspirin/adverse effects/*economics; Cardiovascular Diseases/*economics/mortality/prevention & control; Drug Utilization/economics; Platelet Aggregation Inhibitors/adverse effects/*economics; Practice Patterns, Physicians'/economics; Primary Prevention/*economics; Secondary Prevention/*economics; 00; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PPWM7Q49,conferencePaper,2013,"Busono, Pratondo; Kartini, Evvy",SIMULATION AND PERFORMANCE ANALYSIS OF LITHIUM BATTERY BANK MOUNTED ON THE HYBRID POWER SYSTEM FOR MOBILE PUBLIC HEALTH CENTER,Solid State Ionics: Ionics for Sustainable World,978-981-4439-90-9,,,,"Mobile medical clinic has been proposed to serve homeless people, people in the disaster area or in the remote area where no health service exist. At that site, a number of essential services such as primary health care, general health screening, medical treatment and emergency/rescue operations are required. Such services usually requires on board electrical equipments such as refrigerators, komputer, power tools and medical equipments. To supply such electrical equipments, it needs extra auxiliary power sources, in addition of standard automotive power supply. The auxiliary power source specifically design to supply non automotive load which may have similar configuration, but usually uses high power alternator rated and larger deep cycle on board battery bank. This study covers the modeling and dynamic simulation of auxiliary power source/battery to supply the medical equipment and other electrical equipments on board. It consists a variable speed diesel generator set, photovoltaic (PV) generator mounted on the roof of the car, a rechargable battery bank. As an initial step in the system design, a simulation study was performed. The simulation is conducted in the system level. Simulation results shows that dynamical behaviour by means of current density, voltage and power plot over a chosen time range, and functional behaviour such as charging and discharging characteristic of the battery bank can be obtained.",2013,21/11/2018 10:59,14/04/2020 08:34,,689-697,,,,,,,,,,,"Asian Soc Solid State Ion; Tohoku Univ, IMRAM; Solid State Ion Soc Japan; Sendai Tourism & Convent Bur; Aoba Fdn Promot Engn; Tohoku Univ, IMRAM, Res Cen Sustainable Sci & Eng; Nano Macro Mat Devices & Syst Res Alliance; SOFC Soc Japan; Electrochem Soc Japan, Comm Battery Technol",,,,,,,,,,"

13th Asian Conference on Solid State Ionics - Ionics for Sustainable World, Sendai, JAPAN, JUL 17-20, 2012

",,,00; 100,,"Chowdari, BVR and Kawamura, J and Mizusaki, J and Amezawa, K",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NEF5VXGC,journalArticle,2013,"Abo-Hamad, Waleed; Arisha, Amr",Simulation-based framework to improve patient experience in an emergency department,EUROPEAN JOURNAL OF OPERATIONAL RESEARCH,,0377-2217,10.1016/j.ejor.2012.07.028,,"The global economic crisis has a significant impact on healthcare resource provision worldwide. The management of limited healthcare resources is further challenged by the high level of uncertainty in demand, which can lead to unbalanced utilization of the available resources and a potential deterioration of patient satisfaction in terms of longer waiting times and perceived reduced quality of services. Therefore, healthcare managers require timely and accurate tools to optimize resource utility in a complex and ever-changing patient care process. An interactive simulation-based decision support framework is presented in this paper for healthcare process improvement. Complexity and different levels of variability within the process are incorporated into the process modeling phase, followed by developing a simulation model to examine the impact of potential alternatives. As a performance management tool, balanced scorecard (BSC) is incorporated within the framework to support continual and sustainable improvement by using strategic-linked performance measures and actions. These actions are evaluated by the simulation model developed, whilst the trade-off between objectives, though somewhat conflicting, is analysed by a preference model. The preference model is designed in an interactive and iterative process considering decision makers preferences regarding the selected key performance indicators (KPIs). A detailed implementation of the framework is demonstrated on an emergency department (ED) of an adult teaching hospital in north Dublin, Ireland. The results show that the unblocking of ED outflows by in-patient bed management is more effective than increasing only the ED physical capacity or the ED workforce. (C) 2012 Elsevier BM. All rights reserved.",01/01/2013,21/11/2018 10:59,14/04/2020 08:34,,154-166,,1,224,,,,,,,,,,,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, D279ELEJ,journalArticle,2012,"Griswold, Sharon; Ponnuru, Srikala; Nishisaki, Akira; Szyld, Demian; Davenport, Moira; Deutsch, Ellen S.; Nadkarni, Vinay",The Emerging Role of Simulation Education to Achieve Patient Safety Translating Deliberate Practice and Debriefing to Save Lives,PEDIATRIC CLINICS OF NORTH AMERICA,,0031-3955,10.1016/j.pcl.2012.09.004,,"Simulation-based educational processes are emerging as key tools for assessing and improving patient safety. Multidisciplinary or interprofessional simulation training can be used to optimize crew resource management and safe communication principles. There is good evidence that simulation training improves self-confidence, knowledge, and individual and team performance on manikins. Emerging evidence supports that procedural simulation, deliberate practice, and debriefing can also improve operational performance in clinical settings and can result in safer patient and population/system outcomes in selected settings. This article highlights emerging evidence that shows how simulation-based interventions and education contribute to safer, more efficient systems of care that save lives.",2012-12,21/11/2018 10:59,14/04/2020 08:34,,1329+,,6,59,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2EWKL3MI,journalArticle,2012,"Satter, Rachel M.; Cohen, Trevor; Ortiz, Pierina; Kahol, Kanav; Mackenzie, James; Olson, Carol; Johnson, Mina; Patel, Vimla L.",Avatar-based simulation in the evaluation of diagnosis and management of mental health disorders in primary care,JOURNAL OF BIOMEDICAL INFORMATICS,,1532-0464,10.1016/j.jbi.2012.07.009,,"Major Depressive Disorder (MOD) and Posttraumatic Stress Disorder (PTSD) are highly prevalent illnesses, but the literature suggests they are under-detected and suboptimally managed by primary care practitioners (PCPs). In this paper, we propose and use an evaluation method, using digitally simulated patients (avatars) to evaluate the diagnostic and therapeutic reasoning of PCPs and compared it to the traditional use of paper-based cases. Verbal (think-aloud) protocols were captured in the context of a diagnostic and therapeutic reasoning task. Propositional and semantic representational analysis of simulation data during evaluation, showed specific deficiencies in PCP reasoning, suggesting a promise of this technology in training and evaluation in mental health. Avatars are flexible and easily modifiable and are also a cost-effective and easy-to-disseminate educational tool. (C) 2012 Elsevier Inc. All rights reserved.",2012-12,21/11/2018 10:59,14/04/2020 08:35,,1137-1150,,6,45,,,,,,,,,,,,,,,,,,,,,"Humans; *Computer Simulation; *Primary Health Care; Mental Health; Mental Disorders/*diagnosis/therapy; Physicians, Primary Care/education; Stress Disorders, Post-Traumatic/diagnosis/therapy; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YMRKCQN3,journalArticle,2012,"Riley, Barbara; Norman, Cameron D.; Best, Allan",Knowledge integration in public health: a rapid review using systems thinking,EVIDENCE & POLICY,,1744-2648,10.1332/174426412X660089,,"There are tradeoffs in knowledge synthesis - for example, between comprehensiveness and timeliness, between generalisability and policy relevance. The tradeoffs are particularly challenging for public health. A growing international community is grappling with building more relevant and useful knowledge bases, to facilitate use of this knowledge in policy and practice. These questions guided a knowledge synthesis using a novel `rapid review' methodology. The synthesis used complex adaptive systems as a theoretical lens, in collaboration with an international expert panel. Findings strengthen the call for a systems paradigm in public health, extending theoretical propositions to empirical studies of knowledge generation and use.",2012-11,21/11/2018 10:59,14/04/2020 08:35,,417-431,,4,8,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IX6IMHFL,journalArticle,2012,"Bess, Kimberly D.; Speer, Paul W.; Perkins, Douglas D.",Ecological Contexts in the Development of Coalitions for Youth Violence Prevention: An Organizational Network Analysis,HEALTH EDUCATION & BEHAVIOR,,1090-1981,10.1177/1090198111419656,,"Community coalitions are a recognized strategy for addressing pressing public health problems. Despite the promise of coalitions as an effective prevention strategy, results linking coalition efforts to positive community outcomes are mixed. To date, research has primarily focused on determining organizational attributes related to successful internal coalition functioning. The authors' research complements and adds to this literature by offering a network conceptualization of coalition formation in which coalition participation is studied within the broader context of local organizational networks both within and beyond a coalition. The authors examine participation in the first year of a youth violence prevention coalition exploring both differences between participating and nonparticipating organizations and levels of participation. Each network variable, reflecting prior collaboration and being viewed by other organizations as a local leader, approximately doubled the explained variance in coalition participation beyond the predictive power of all available organizational attributes combined. Results suggest that initial coalition participation emerged out of a preexisting network of interorganizational relations and provide an alternative perspective on coalition formation that goes beyond conceptual orientations that treat coalitions as bounded organizational entities that exist apart from the communities in which they are embedded.",2012-10,21/11/2018 10:59,14/04/2020 08:34,,526-537,,5,39,,,,,,,,,,,,,,,,,,,,,Humans; Qualitative Research; Adolescent; *Program Development; Community Networks/*organization & administration; Tennessee; Violence/*prevention & control; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WBCTBL95,journalArticle,2012,"Chuang, Li-Yeh; Chang, Hsueh-Wei; Lin, Ming-Cheng; Yang, Cheng-Hong",Chaotic particle swarm optimization for detecting SNP-SNP interactions for CXCL12-related genes in breast cancer prevention,EUROPEAN JOURNAL OF CANCER PREVENTION,,0959-8278,10.1097/CEJ.0b013e32834e31f6,,"Genome-wide association studies have revealed that many single nucleotide polymorphisms (SNPs) are associated with breast cancer, and yet the potential SNP-SNP interactions have not been well addressed to date. This study aims to develop a methodology for the selection of SNP-genotype combinations with a maximum difference between case and control groups. We propose a new chaotic particle swarm optimization (CPSO) algorithm that identifies the best SNP combinations for breast cancer association studies containing seven SNPs. Five scoring functions, that is, the percentage correct, sensitivity/specificity, positive predictive value/negative predictive value, risk ratio, and odds ratio, are provided for evaluating SNP interactions in different SNP combinations. The CPSO algorithm identified the best SNP combinations associated with breast cancer protection. Some SNP interactions in specific SNPs and their corresponding genotypes were revealed. These SNP combinations showed a significant association with breast cancer protection (P<0.05). The sensitivity and specificity of the respective best SNP combinations were all higher than 90%. In contrast to the corresponding non-SNP-SNP interaction combinations, the estimated odds ratio and risk ratio of the SNP-SNP interaction in SNP combinations for breast cancer were less than 100%. This suggests that CPSO can successfully identify the best SNP combinations for breast cancer protection. In conclusion, we focus on developing a methodology for the selection of SNP-genotype combinations with a maximum difference between case and control groups. The CPSO method can effectively identify SNP-SNP interactions in complex biological relationships underlying the progression of breast cancer. European Journal of Cancer Prevention 21:336-342 (C) 2012 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.",2012-07,21/11/2018 10:59,14/04/2020 08:34,,336-342,,4,21,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6E72NRYL,journalArticle,2012,"Manley, Matthew; Kim, Yong Seog",Modeling emergency evacuation of individuals with disabilities (exitus): An agent-based public decision support system,EXPERT SYSTEMS WITH APPLICATIONS,,0957-4174,10.1016/j.eswa.2012.01.169,,"In this paper, we present a public decision support system (DSS) distinguished from various DSSs in the private business sector in terms of its ownership, data scarcity, and beneficiaries. In particular, our system is intended to play a vital role in assessing and optimizing emergency response plans for rare but catastrophic events such as the September 11th attacks. While taking an agent-based microscopic simulation approach in a hierarchical framework, we used our model to estimate the effectiveness of alternative evacuation strategies to support emergency response planning as a part of business continuity planning for all private business organizations. The presented model is unique because it considers individuals with disabilities explicitly in terms of speed, ability to negotiate the environment, and normalcy bias depending on type of disability. It is also capable of classifying the environment in terms of accessibility characteristics encompassing various conditions which have been shown to have a disproportionate effect upon the behavior of individuals with disabilities during an emergency. Through a series of simulation experiments, our system identified specific locations (e.g., the NW landing) on the 3rd floor of the test bed building as possible bottleneck spots under certain conditions (e.g., the sharp increase in individuals with disabilities among residents). This way, our system provides the architect with tools to test the structure's design to determine how well it meets the identified requirements for emergency evacuation to accommodate this shifting demographic. In particular, our system strongly demonstrated the effectiveness of new emergency evacuation strategies for individuals with disabilities such as assisted evacuations which allows other healthy people to play more active roles compared to traditional strategies in which individuals with disabilities are helplessly waiting for assistants such as fire fighters at the designated area. Our system also revealed that people using wheelchairs and those with lower stamina were at the greatest risk. People with lower stamina such as the elderly, people with chronic health conditions, or those with temporary injuries are at a greater risk mainly because they are not easily identifiable. Ultimately, the proposed DSS system can be used to inform public policy professionals of more effective, evidence-based evacuation planning and environmental design methods based on a better understanding of the behavior of individuals with disabilities. (c) 2012 Elsevier Ltd. All rights reserved.",2012-07,21/11/2018 10:59,14/04/2020 08:34,,8300-8311,,9,39,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LA9FCFRT,journalArticle,2012,"Lasry, Arielle; Sansom, Stephanie L.; Hicks, Katherine A.; Uzunangelov, Vladislav",Allocating HIV Prevention Funds in the United States: Recommendations from an Optimization Model,PLOS ONE,,1932-6203,10.1371/journal.pone.0037545,,"The Centers for Disease Control and Prevention (CDC) had an annual budget of approximately $327 million to fund health departments and community-based organizations for core HIV testing and prevention programs domestically between 2001 and 2006. Annual HIV incidence has been relatively stable since the year 2000 [1] and was estimated at 48,600 cases in 2006 and 48,100 in 2009 [2]. Using estimates on HIV incidence, prevalence, prevention program costs and benefits, and current spending, we created an HIV resource allocation model that can generate a mathematically optimal allocation of the Division of HIV/AIDS Prevention's extramural budget for HIV testing, and counseling and education programs. The model's data inputs and methods were reviewed by subject matter experts internal and external to the CDC via an extensive validation process. The model projects the HIV epidemic for the United States under different allocation strategies under a fixed budget. Our objective is to support national HIV prevention planning efforts and inform the decision-making process for HIV resource allocation. Model results can be summarized into three main recommendations. First, more funds should be allocated to testing and these should further target men who have sex with men and injecting drug users. Second, counseling and education interventions ought to provide a greater focus on HIV positive persons who are aware of their status. And lastly, interventions should target those at high risk for transmitting or acquiring HIV, rather than lower-risk members of the general population. The main conclusions of the HIV resource allocation model have played a role in the introduction of new programs and provide valuable guidance to target resources and improve the impact of HIV prevention efforts in the United States.",06/06/2012,21/11/2018 10:59,14/04/2020 08:34,,,,6,7,,,,,,,,,,,,,,,,,,,,,1; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VSMPQTGR,journalArticle,2012,"Roggendorf, H.; Furtenhofer, C.; Ophoff, J.; Dembinski, K.; Powalla, B.; Freynik, P.",Optimization of vaccination protection of children and adolescents. Possibilities in the public health sector (PHS),MONATSSCHRIFT KINDERHEILKUNDE,,0026-9298,10.1007/s00112-011-2616-y,,"In Germany, several outbreaks of measles have occurred in recent years. In 2011 almost 1,600 cases of measles have been registered at the Robert Koch Institute (RKI). Obviously, there are severe shortcomings in vaccination rates for this and other infectious diseases. Annual, individual vaccination counseling covering the entire city of Essen (15,000 children) in kindergartens, at school entry and in the 7th grade as well as projects, such as vaccination classes by medical students or on-site vaccination campaigns are conducted by the Youth Health Service. Through the yearly vaccination counseling in kindergartens 91% of the children entering school have already been vaccinated twice against measles, mumps and German measles (MMR) in the year 2008. Vaccination rates for hepatitis B and the second MMR vaccination increased by 16% as a result of the vaccination recommendations given. About 90% of the students of a senior college had complete protection against MMR following one of the campaigns. A continual reminder to the parents with regards to necessary vaccinations is an important part of the prevention of infectious diseases. The measures are effective, easily performed and a model which could be implemented in community health centers throughout the country.",2012-06,21/11/2018 10:59,14/04/2020 08:35,,572-578,,6,160,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VL94CGRD,journalArticle,2012,"Candelieri, Antonio; Giordani, Ilaria; Testa, Paolo; Arosio, Gaia; Archetti, Francesco",A MARKOV-BASED MODEL TO FORECAST EMERGENCY HOSPITAL ADMISSIONS DUE TO AIR POLLUTION: THE LENVIS PROJECT APPROACH,ENVIRONMENTAL ENGINEERING AND MANAGEMENT JOURNAL,,1582-9596,10.30638/eemj.2012.123,,"Several epidemiological studies proved pollutant levels and exposure may increase risk of morbidity and mortality, in particular for respiratory and cardiovascular diseases. However, performing a short term estimation of the hospital admissions due to air quality remains difficult even if crucial for a rational healthcare management. In this paper we present a Markov based approach aimed at estimating short term emergency hospital admission trends. This predictive model has been developed within the European project Lenvis (Local ENVIronmental Services), a collaborative network of services able to retrieve and analyze heterogeneous and geographically dispersed data sources in order to deliver environment and health information. One of the services of Lenvis is the Health Impact Decision Support System (HIDSS) whose inferential engine is provided by a Markov-based model trained on real data related to pollutant levels and emergency hospital admissions in Milan, Italy. HIDSS has shown, in several use cases, its usefulness both for environment authorities and healthcare stakeholders.",2012-05,21/11/2018 10:59,14/04/2020 08:34,,999-1008,,5,11,,,,,,,,,,,,,,,,,,"

Lenvis Symposium on Localized Environmental Services for all Citizens, Delft, NETHERLANDS, NOV 28-29, 2011

",,,1; 310; markov,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QVK5YZ92,journalArticle,2012,"Durmaz, Aylin; Dicle, Aklime; Cakan, Emre; Cakir, Sen",Effect of Screen-Based Computer Simulation on Knowledge and Skill in Nursing Students' Learning of Preoperative and Postoperative Care Management A Randomized Controlled Study,CIN-COMPUTERS INFORMATICS NURSING,,1538-2931,10.1097/NCN.0b013e3182419134,,"Screen-based computer simulations are considered a method of skill teaching in health education. This study examined the effect of screen-based computer simulation on knowledge, skill, and the clinical decision-making process in teaching preoperative and postoperative care management to second-year students in an undergraduate school of nursing. It is a randomized controlled study. The study sample was composed of 82 students. They received education in screen-based computer simulation (n = 41) and skill laboratories (n = 41). Three instruments were used: a preoperative and postoperative care management cognitive level assessment test, skill control lists of preoperative and postoperative care management, and the Clinical Decision Making in Nursing Scale. There was not a significant difference between the students' posteducation knowledge levels (P = .421), practical deep breathing and coughing exercise education skills (P = .867), or clinical decision-making scale total and subscale scores (P = .065). However, a significant difference was found between the admission of the patient in the surgical clinic after surgery skill scores of the students (P = .04). Education provided in the screen-based computer simulation laboratory was equivalent to that provided in the skill laboratory.",2012-04,21/11/2018 10:59,14/04/2020 08:34,,196-203,,4,30,,,,,,,,,,,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, AQHFUR5D,journalArticle,2012,"Rice, Eric; Tulbert, Eve; Cederbaum, Julie; Adhikari, Anamika Barman; Milburn, Norweeta G.",Mobilizing homeless youth for HIV prevention: a social network analysis of the acceptability of a face-to-face and online social networking intervention,HEALTH EDUCATION RESEARCH,,0268-1153,10.1093/her/cyr113,,"The objective of the study is to use social network analysis to examine the acceptability of a youth-led, hybrid face-to-face and online social networking HIV prevention program for homeless youth.Seven peer leaders (PLs) engaged face-to-face homeless youth (F2F) in the creation of digital media projects (e.g. You Tube videos). PL and F2F recruited online youth (OY) to participate in MySpace and Facebook communities where digital media was disseminated and discussed. The resulting social networks were assessed with respect to size, growth, density, relative centrality of positions and homophily of ties. Seven PL, 53 F2F and 103 OY created two large networks. After the first 50 F2F youth participated, online networks entered a rapid growth phase. OY were among the most central youth in these networks. Younger aged persons and females were disproportionately connected to like youth. The program appears highly acceptable to homeless youth. Social network analysis revealed which PL were the most critical to the program and which types of participants (younger youth and females) may require additional outreach efforts in the future.",2012-04,21/11/2018 10:59,14/04/2020 08:35,,226-236,,2,27,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XNCJK9HW,journalArticle,2012,"Liu, Nan; D'Aunno, Thomas",The Productivity and Cost-Efficiency of Models for Involving Nurse Practitioners in Primary Care: A Perspective from Queueing Analysis,HEALTH SERVICES RESEARCH,,0017-9124,10.1111/j.1475-6773.2011.01343.x,,"Objective. To develop simple stylized models for evaluating the productivity and cost-efficiencies of different practice models to involve nurse practitioners (NPs) in primary care, and in particular to generate insights on what affects the performance of these models and how. D ata Sources and Study Design. The productivity of a practice model is defined as the maximum number of patients that can be accounted for by the model under a given timeliness-to-care requirement; cost-efficiency is measured by the corresponding annual cost per patient in that model. Appropriate queueing analysis is conducted to generate formulas and values for these two performance measures. Model parameters for the analysis are extracted from the previous literature and survey reports. Sensitivity analysis is conducted to investigate the model performance under different scenarios and to verify the robustness of findings. Principal Findings. Employing an NP, whose salary is usually lower than a primary care physician, may not be cost-efficient, in particular when the NP's capacity is underutilized. Besides provider service rates, workload allocation among providers is one of the most important determinants for the cost-efficiency of a practice model involving NPs. Capacity pooling among providers could be a helpful strategy to improve efficiency in care delivery. Conclusions. The productivity and cost-efficiency of a practice model depend heavily on how providers organize their work and a variety of other factors related to the practice environment. Queueing theory provides useful tools to take into account these factors in making strategic decisions on staffing and panel size selection for a practice model.",2012-04,21/11/2018 10:59,14/04/2020 08:34,,594-613,,2,47,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, C8KMQWT7,journalArticle,2012,"Dai, James Y.; Gilbert, Peter B.; Masse, Benoit R.",Partially Hidden Markov Model for Time-Varying Principal Stratification in HIV Prevention Trials,JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION,,0162-1459,10.1080/01621459.2011.643743,,"It is frequently of interest to estimate the intervention effect that adjusts for post-randomization variables in clinical trials. In the recently completed HPTN 035 trial, there is differential condom use between the three microbicide gel arms and the no-gel control arm, so intention-to-treat (ITT) analyses only assess the net treatment effect that includes the indirect treatment effect mediated through differential condom use. Various statistical methods in causal inference have been developed to adjust for post-randomization variables. We extend the principal stratification framework to time-varying behavioral variables in HIV prevention trials with a time-to-event endpoint, using a partially hidden Markov model (pHMM). We formulate the causal estimand of interest, establish assumptions that enable identifiability of the causal parameters, and develop maximum likelihood methods for estimation. Application of our model on the HPTN 035 trial reveals an interesting pattern of prevention effectiveness among different condom-use principal strata.",2012-03,21/11/2018 10:59,14/04/2020 08:34,,52-65,,497,107,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UDAT2ZLJ,journalArticle,2012,"Zhang, Yue; Puterman, Martin L.; Nelson, Matthew; Atkins, Derek",A Simulation Optimization Approach to Long-Term Care Capacity Planning,OPERATIONS RESEARCH,,0030-364X,10.1287/opre.1110.1026,,"This paper describes a methodology for setting long-term care capacity levels over a multiyear planning horizon to achieve target wait time service levels. Our approach integrates demographic and survival analysis, discrete event simulation, and optimization. Based on this methodology, we developed a decision support system for use in practice. We illustrate this approach through two case studies; one for a regional health authority in British Columbia, Canada, and the other for a long-term care facility. We also compare our approach to the fixed ratio approach used in practice and the SIPP (stationary, independent, period by period) and MOL (modified offered load) approaches developed in the call center literature. Our results suggest that our approach is preferable. The fixed ratio approach lacks a rigorous foundation, and the SIPP and MOL approaches do not perform reliably mainly because of long service times. We conclude the paper with policy recommendations.",2012-04,21/11/2018 10:59,14/04/2020 08:34,,249-261,,2,60,,,,,,,,,,,,,,,,,,,,,1; Discrete event; 320,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, SGQ7QWTU,journalArticle,2012,"Bower, Peter; Kennedy, Anne; Reeves, David; Rogers, Anne; Blakeman, Tom; Chew-Graham, Carolyn; Bowen, Robert; Eden, Martin; Gardner, Caroline; Hann, Mark; Lee, Victoria; Morris, Rebecca; Protheroe, Joanne; Richardson, Gerry; Sanders, Caroline; Swallow, Angela; Thompson, David",A cluster randomised controlled trial of the clinical and cost-effectiveness of a `whole systems' model of self-management support for the management of long- term conditions in primary care: trial protocol,IMPLEMENTATION SCIENCE,,1748-5908,10.1186/1748-5908-7-7,,"Background: Patients with long-term conditions are increasingly the focus of quality improvement activities in health services to reduce the impact of these conditions on quality of life and to reduce the burden on care utilisation. There is significant interest in the potential for self-management support to improve health and reduce utilisation in these patient populations, but little consensus concerning the optimal model that would best provide such support. We describe the implementation and evaluation of self-management support through an evidence-based `whole systems' model involving patient support, training for primary care teams, and service re-organisation, all integrated into routine delivery within primary care. Methods: The evaluation involves a large-scale, multi-site study of the implementation, effectiveness, and cost-effectiveness of this model of self-management support using a cluster randomised controlled trial in patients with three long-term conditions of diabetes, chronic obstructive pulmonary disease (COPD), and irritable bowel syndrome (IBS). The outcome measures include healthcare utilisation and quality of life. We describe the methods of the cluster randomised trial. Discussion: If the `whole systems' model proves effective and cost-effective, it will provide decision-makers with a model for the delivery of self-management support for populations with long-term conditions that can be implemented widely to maximise `reach' across the wider patient population.",26/01/2012,21/11/2018 10:59,14/04/2020 08:34,,,,,7,,,,,,,,,,,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KIF4RWWE,conferencePaper,2012,"Thorwarth, Michael; Arisha, Amr",A SIMULATION-BASED DECISION SUPPORT SYSTEM TO MODEL COMPLEX DEMAND DRIVEN HEALTHCARE FACILITIES,2012 WINTER SIMULATION CONFERENCE (WSC),978-1-4673-4779-2 978-1-4673-4780-8,,,,"Simulating healthcare processes is a sophisticated endeavor. Treatment processes and patient arrival patterns differ significantly in their statistical attributes and implicate a high degree of variability. In addition, there are several types of interconnected processes of medical staff involved that accompany a patient's journey through the healthcare facility. Replicating this behavior with process flow models in a discrete event simulation model is highly complex and therefore difficult to create while maintaining a high degree of precision. A framework is thus introduced which delivers an algorithm that allows to implement Multiple Participant Pathway Modeling (MPPM) under the consideration of Flexible Resource Allocation (FRA). This framework is applied on an Irish Emergency Department (ED), the outcome of which is presented here. Results show that scenarios can be investigated which impact several different process flows with a high precision. This provides a solid base for both the interpretation of results and decision making.",2012,21/11/2018 10:59,14/04/2020 08:35,,,,,,,,,Winter Simulation Conference Proceedings,,,,,,,,,,,,,,"

Winter Simulation Conference (WSC), Berlin, GERMANY, DEC 09-12, 2012

",,,1; 110,,"Laroque, C and Himmelspach, J and Pasupathy, R",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CK2H6G9L,journalArticle,2012,"Mistry, Hema; Morris, Stephen; Dyer, Matthew; Kotseva, Kornelia; Wood, David; Buxton, Martin; Grp, EUROACTION Study",Cost-effectiveness of a European preventive cardiology programme in primary care: a Markov modelling approach,BMJ OPEN,,2044-6055,10.1136/bmjopen-2012-001029,,"Objective: To investigate the longer-term cost-effectiveness of a nurse-coordinated preventive cardiology programme for primary prevention of cardiovascular disease (CVD) compared to routine practice from a health service perspective. Design: A matched, paired cluster-randomised controlled trial. Setting: Six pairs of general practices in six countries. Participants: 1019 patients were randomised to the EUROACTION intervention programme and 1005 patients to usual care (UC) and who completed the 1-year follow-up. Outcome measures: Evidence on health outcomes and costs was based on patient-level data from the study, which had a 1-year follow-up period. Future risk of CVD events was modelled, using published risk models based on patient characteristics. An individual-level Markov model for each patient was used to extrapolate beyond the end of the trial, which was populated with data from published sources. We used an 11-year time horizon and investigated the impact on the cost-effectiveness of varying the duration of the effect of the intervention beyond the end of the trial. Results are expressed as incremental cost per quality-adjusted life-year gained. Results: Unadjusted results found the intervention to be more costly and also more effective than UC. However, after adjusting for differences in age, gender, country and baseline risk factors, the intervention was dominated by UC, but this analysis was not able to take into account the lifestyle changes in terms of diet and physical activity. Conclusions: Although the EUROACTION study achieved healthier lifestyle changes and improvements in management of blood pressure and lipids for patients at high risk of CVD, compared to UC, it was not possible to show, using available risk equations which do not incorporate diet and physical activity, that the intervention reduced longer-term cardiovascular risk cost-effectively. Whether or not an intervention such as that offered by EUROACTION is cost-effective requires a longer-term trial with major cardiovascular events as the outcome. Trial Registration number: ISRCTN 71715857.",2012,21/11/2018 10:59,14/04/2020 08:34,,,,5,2,,,,,,,,,,,,,,,,,,,,,1; Markov; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Z45Z52YD,journalArticle,2012,"Vyas, Deepti; McCulloh, Russell; Dyer, Carla; Gregory, Gretchen; Higbee, Dena",An Interprofessional Course Using Human Patient Simulation to Teach Patient Safety and Teamwork Skills,AMERICAN JOURNAL OF PHARMACEUTICAL EDUCATION,,0002-9459,10.5688/ajpe76471,,"Objectives. To assess the effectiveness of human patient simulation to teach patient safety, team-building skills, and the value of interprofessional collaboration to pharmacy students. Design. Five scenarios simulating semi-urgent situations that required interprofessional collaboration were developed. Groups of 10 to 12 health professions students that included 1 to 2 pharmacy students evaluated patients while addressing patient safety hazards. Assessment. Pharmacy students' scores on 8 of 30 items on a post-simulation survey of knowledge, skills, and attitudes improved over pre-simulation scores. Students' scores on 3 of 10 items on a team building and interprofessional communications survey also improved after participating in the simulation exercise. Over 90% of students reported that simulation increased their understanding of professional roles and the importance of interprofessional communication. Conclusions. Simulation training provided an opportunity to improve pharmacy students' ability to recognize and react to patient safety concerns and enhanced their interprofessional collaboration and communication skills.",2012,21/11/2018 10:59,14/04/2020 08:35,,,,4,76,,,,,,,,,,,,,,,,,,,,,"Humans; *Patient Simulation; Patient Safety/*standards; Interprofessional Relations; Professional Role; patient safety; *Cooperative Behavior; *Patient Care Team; Attitude of Health Personnel; simulation; *Students, Pharmacy; 00; Education, Pharmacy/*methods; emergency department; interprofessional; team work; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GE883JQG,journalArticle,2011,"Sokolova, Marina V.; Fernandez-Caballero, Antonio",Hybrid models in agent-based environmental decision support,APPLIED SOFT COMPUTING,,1568-4946,10.1016/j.asoc.2011.05.035,,"Providing informational support in decision making is one of the priority directions of research in the sphere of public health management. Modern approaches suggest wide usage of intelligent data mining methods and Web-services, but just a few enable to study a complex system from an interdisciplinary point of view. In this paper an agent-based decision support system (ADSS), which embodies the principles of the interdisciplinary approach and facilitates multi-focal view and examination of the “Environment-Public health” system, is introduced. The detailed design of the system with the emphasis on the roles, scenarios and its implementation is presented. The data mining procedures used for data preparation, modeling and simulation, which include statistics, methods of artificial intelligence and hybrid models in form of cascade committee machines, are described. Then, the advantages of the proposed hybrid models against “singular” modeling methods are demonstrated. Finally, a case study for a selected region is presented and its results are discussed. (C) 2011 Elsevier B.V. All rights reserved.",2011-12,21/11/2018 10:59,14/04/2020 08:35,,5243-5258,,8,11,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MVICVY73,journalArticle,2011,"Ozgen, Senay; Busse, James S.; Palta, Jiwan P.",Influence of Root Zone Calcium on Shoot Tip Necrosis and Apical Dominance of Potato Shoot: Simulation of This Disorder by Ethylene Glycol Tetra Acetic Acid and Prevention by Strontium,HORTSCIENCE,,0018-5345,,,"The important roles of calcium on plant growth and development including cell division and cell elongation is well documented. The purpose of the present study was to determine the impact of root zone calcium on the growth and health of potato apical meristem and on the maintenance of apical dominance. For this purpose, single-node potato cuttings (Salaam?, tuberosum L. cv. Dark Red Norland) were grown in sterilized modified Murashige and Skoog (MS) media containing varying concentrations of calcium (1 to 3000 mu M). After 13 to 30 d of growth, plantlets were harvested and data for height of the main shoot and for the number of axillary shoots produced were recorded. Plantlets were ashed and tissue calcium concentration was determined. Shoot height was retarded with decreasing concentration of calcium in the media. Calcium deficiency induced shoot tip injury and loss of apical dominance. Tip injury was followed by the development of axillary shoots. The number of axillary shoots increased from one to 21 as calcium concentration in the media decreased from 3000 to 1 mu M. At calcium concentration of 1500 mu M or higher, there was a single main shoot with no axillary shoots. Addition of ethylene glycol tetra acetic acid (EGTA), a calcium chelator, to the media with 2720 mu M calcium (sufficient calcium) resulted in the development of shoot injury and in the formation of axillary shoots. Calcium deficiency injury symptoms were prevented by the addition of a calcium analog, strontium, to MS media deficient in calcium. Strontium has been reported to strongly bind to plant cell walls and the inclusion of strontium prevented injury in shoots of plants grown on calcium-deficient media. These results suggest that strontium is able to mimic the role of calcium in the maintenance of cell wall integrity and supports previous studies that showed that calcium deficiency results from cell wall collapse of the subapical cells.",2011-10,21/11/2018 10:59,14/04/2020 08:35,,1358-1362,,10,46,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EZ9J4H4E,journalArticle,2011,"Ikeda, Nayu; Shibuya, Kenji; Hashimoto, Hideki",Improving Population Health Measurement in National Household Surveys: A Simulation Study of the Sample Design of the Comprehensive Survey of Living Conditions of the People on Health and Welfare in Japan,JOURNAL OF EPIDEMIOLOGY,,0917-5040,10.2188/jea.JE20100102,,"Background: The Comprehensive Survey of Living Conditions of the People on Health and Welfare (CSLC) is a major source of health data in Japan. The CSLC is not strictly based on probabilistic sampling, but instead uses an equal allocation of sample clusters to yield equal standard errors of estimates across prefectures. This study compared the performance of this sample design in measuring population health with that of an alternative probabilistic sampling approach. Methods: A simulation analysis was conducted using hypothetical population data (n = 34 262 865) from which 1000 sample datasets were randomly drawn using 2 sampling methods, namely, a conventional stratified random sampling of a constant number of clusters and an alternative 2-stage cluster sampling of households with probability proportional to size. The root mean squared error was used to measure the accuracy of estimated means of a continuous variable and proportions of its dichotomized variable. Results: The alternative method reduced the variability of estimates in the total population and by strata. It improved further with an increased number of sample clusters in conjunction with a reduced sampling rate of households from selected clusters. Conclusions: The alternative sample design increased the overall accuracy of population estimates of continuous and dichotomous variables from the CSLC. These benefits should be carefully weighed against the costs incurred in traveling to additional clusters in large prefectures. Further simulation research is necessary to investigate the performance of sampling designs for nominal and ordinal response variables.",2011-09,21/11/2018 10:59,14/04/2020 08:34,,385-390,,5,21,,,,,,,,,,,,,,,,,,,,,Humans; Reproducibility of Results; Computer Simulation; Research Design; Japan; 00; *Family Characteristics; Health Surveys/*methods; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, C4LEFZBH,journalArticle,2011,"Cooper, Jeffrey B.; Singer, Sara J.; Hayes, Jennifer; Sales, Michael; Vogt, Jay W.; Raemer, Daniel; Meyer, Gregg S.","Design and Evaluation of Simulation Scenarios for a Program Introducing Patient Safety, Teamwork, Safety Leadership, and Simulation to Healthcare Leaders and Managers",SIMULATION IN HEALTHCARE,,1559-2332,10.1097/SIH.0b013e31821da9ec,,"We developed a training program to introduce managers and informal leaders of healthcare organizations to key concepts of teamwork, safety leadership, and simulation to motivate them to act as leaders to improve safety within their sphere of influence. This report describes the simulation scenario and debriefing that are core elements of that program. Twelve teams of clinician and nonclinician managers were selected from a larger set of volunteers to participate in a 1-day, multielement training program. Two simulation exercises were developed: one for teams of nonclinicians and the other for clinicians or mixed groups. The scenarios represented two different clinical situations, each designed to engage participants in discussions of their safety leadership and teamwork issues immediately after the experience. In the scenarios for nonclinicians, participants conducted an anesthetic induction and then managed an ethical situation. The scenario for clinicians simulated a consulting visit to an emergency room that evolved into a problem-solving challenge. Participants in this scenario had a limited time to prepare advice for hospital leadership on how to improve observed safety and cultural deficiencies. Debriefings after both types of scenarios were conducted using principles of “debriefing with good judgment.” We assessed the relevance and impact of the program by analyzing participant reactions to the simulation through transcript data and facilitator observations as well as a postcourse questionnaire. The teams generally reported positive perceptions of the relevance and quality of the simulation with varying types and degrees of impact on their leadership and teamwork behaviors. These kinds of clinical simulation exercises can be used to teach healthcare leaders and managers safety leadership and teamwork skills and behaviors. (Sim Healthcare 6: 231-238, 2011)",2011-08,21/11/2018 10:59,14/04/2020 08:34,,231-238,,4,6,,,,,,,,,,,,,,,,,,,,,"Humans; Medical Errors/prevention & control; Emergency Service, Hospital; Program Development; Health Personnel/*education; *Cooperative Behavior; *Leadership; *Safety Management; Problem-Based Learning; Teaching/*methods; 00; New England; Health Facility Administrators/*education; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ZM7J692P,journalArticle,2011,"Yang, Xuebing; Miao, Yuan",Distributed Agent Based Interoperable Virtual EMR System for Healthcare System Integration,JOURNAL OF MEDICAL SYSTEMS,,0148-5598,10.1007/s10916-009-9367-5,,"One of the major problems in health care system integration is the formidable cost of mediating between myriad vendors and policy makers for updating existing heterogeneous systems to support a great variety of standards or interfaces. To provide cost-effective healthcare system integration solution, this paper presents a Graphical User Interface state model (GUISM) for automatically exchanging information with existing healthcare software through their GUIs with no modifications needed to them. This can save the huge cost of upgrading, testing and redeploying the existing systems. By using the GUISM model, distributed agents are deployed to the client computers interacting with the local electronic medical system (EMR) for communicating with other EMR systems. The whole system is called virtual EMR system and each client in this system can request needed patient healthcare information without knowing the actual location of the data.",2011-06,21/11/2018 10:59,14/04/2020 08:35,,309-319,,3,35,,,,,,,,,,,,,,,,,,,,,Humans; Systems Integration; Software; *User-Computer Interface; Organizational Innovation; 1; *Electronic Health Records/instrumentation/organization & administration; Information Dissemination/*methods; Medical Informatics Applications; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4Q3ZC43Q,journalArticle,2011,"Pernar, Luise I. M.; Shaw, Tim J.; Pozner, Charles N.; Vogelgesang, Kaitlin R.; Peyre, Sarah E.",A Checklist for a Central Venous Line-Based Simulation Scenario to Measure Behavioral Compliance With Joint Commission National Patient Safety Goals,SIMULATION IN HEALTHCARE,,1559-2332,10.1097/SIH.0b013e318213611e,,,2011-04,21/11/2018 11:00,14/04/2020 08:35,,117-120,,2,6,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 78WXIP63,journalArticle,2011,"Isern, David; Moreno, Antonio; Sanchez, David; Hajnal, Akos; Pedone, Gianfranco; Varga, Laszlo Z.",Agent-based execution of personalised home care treatments,APPLIED IN℡LIGENCE,,0924-669X,10.1007/s10489-009-0187-6,,"Home Care services are notoriously difficult to deliver efficiently, due to the heterogeneity of the involved actors and the usual co-morbidity of the patients assisted at home. The K4Care platform proposes an agent-based three-layered architecture aimed at addressing these two issues and facilitate the provision of these services. The development of the platform was supported by a methodology to help the automation of the modelling and implementation of the multi-agent system. The intelligent agents of the platform, which personify the Home Care domain actors, have the capability to guide the execution of administrative and medical processes, driving the flux of knowledge and control among all the involved professionals, simplifying their interactions and capturing new medical knowledge emerging from physicians. The platform also provides tools that allow medical practitioners to develop personalised treatments, adapted to the clinical and social circumstances of each patient and based on the standard international recommendations for the most frequent Home Care pathologies. The paper describes the architecture of the system, how personalised treatments are created, and how they are executed through the co-ordinated work of agents. A comparison with other relevant guideline execution systems and an evaluation of the actual state of the work are also provided.",2011-04,21/11/2018 11:00,14/04/2020 08:34,,155-180,,2,34,,,,,,,,,,,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WIKKVF68,journalArticle,2011,"McEwen, Timothy R.; Elder, Nancy C.; Flach, John M.",Creating Safety in Primary Care Practice with Electronic Medical Records Requires the Consideration of System Dynamics,JOURNAL OF HEALTHCARE ENGINEERING,,2040-2295,10.1260/2040-2295.2.1.87,,"Improvement in quality and safety in health care often depends on eliminating errors. Using examples from our research on the medical testing processes in primary care medical practices, we argue that designing safer systems requires moving beyond frameworks that focus exclusively on error elimination to consider the broader system dynamics including information loops that can be critical to the overall stability of the system. We focus on describing the nature of information coupling in relation to the constructs of essential friction, autonomation, and ecological interface design and how these can lead to more resilient systems. With the recent push in the United States to move towards electronic medical records (EMR), we conclude with suggestions for improving EMR systems based on these concepts.",2011-03,21/11/2018 11:00,14/04/2020 08:34,,87-96,,1,2,,,,,,,,,,,,,,,,,,,,,System dynamics; 1; ******To read; X,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NGHMXVLZ,conferencePaper,2011,"Ciorap, Radu; Corciova, Calin; Ciorap, Mariana; Zaharia, Dan",Optimization of the Treatment for Chronic Disease Using an e-Health System,2011 7TH INTERNATIONAL SYMPOSIUM ON ADVANCED TOPICS IN ELECTRICAL ENGINEERING (ATEE),978-1-4577-0507-6,,,,"Nowadays in most European countries the health systems are pressed by massive requests for assisting a growing number of people suffering from chronic diseases. The present work refers to an e-Health monitoring system dedicated to patients with chronic diseases. The system includes a medical device for monitoring some vital parameters on patients that alongside a software application, it provides an integrated solution of monitoring the evolution of the disease in order to optimize the treatment.",2011,21/11/2018 11:00,14/04/2020 08:34,,,,,,,,,International Symposium on Advanced Topics in Electrical Engineering,,,,Inst Elect & Elect Engineers,,,,,,,,,,"

7th International Symposium on Advanced Topics in Electrical Engineering (ATEE), Bucharest, ROMANIA, MAY 12-14, 2011

",,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XHNFBVTH,conferencePaper,2011,"Yang, Qing; Yang, Fan",Multi-agents Simulation on Unconventional Emergencies Evolution Mechanism in Public Health,"ADVANCES IN MULTIMEDIA, SOFTWARE ENGINEERING AND COMPUTING, VOL 2",978-3-642-25985-2,,,,"Based on the cellular automaton principle and multi-agents theory of complex systems, this essay studied the public health unconventional emergencies generation and evolution mechanism, established evolution model and carried out simulation of the public health unconventional emergencies evolution mechanism, and finally took SARS emergency for an example. Research results showed that the evolution of the public health emergency often promots other linkage emergencies, the damage of linkage system is larger than that of promotion system, and the damage is uncontrolled except for controlling the promotion system effectively, just like isolation measures or inject vaccine for individual of the promotion system so as to prevent promotion system from producing linkage hazards.",2011,21/11/2018 11:00,14/04/2020 08:35,,509-514,,,129,,,,Advances in Intelligent and Soft Computing,,,,Int Sci & Educ Res Assoc; Beijing Gireida Educ Co Ltd; Wuhan Univ Sci & Technol,,,,,,,,,,"

International Conference on Multimedia, Software Engineering and Computing, Wuhan, PEOPLES R CHINA, NOV 26-27, 2011

",,,1; 110,,"Jin, D and Lin, S",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3SYQT6A4,conferencePaper,2011,"Bacioiu, George M.; Pasek, Zbigniew J.",Systems Dynamics Simulation Approach to a Personalized Obesity Decision Support System Model,2011 E-HEALTH AND BIOENGINEERING CONFERENCE (EHB),978-1-4577-0292-1,,,,"Internationally, at the population level, a review of overweight/obesity prevalence trends reveals consistent increase of the condition in industrialized nations, but considerable variability internationally in the magnitude of the change. Unlike other approaches to reduce obesity that rely in expert design of someone's strategy, the decision support model (DSM) proposed by this research goes beyond simply providing a weight loss plan. Arguably, such an approach is one of the major weaknesses of many attempts targeting solutions to the obesity problem. The majority of the efforts fail, if not immediately, months or years after a successful drop in the weight. The proposed DSM employs a multidisciplinary dynamic systems approach. There is little evidence of the use of SD in a healthcare environment for modeling the human body, and, even less in obesity control. The outcome of the DSM accounts for the differences between individuals, so they are able to develop strategies based on their own preferences. The DSM is modular and will allow for the addition of other factors such as non-physical - e.g. emotional, stress, and motivation.",2011,21/11/2018 11:00,14/04/2020 08:34,,,,,,,,,E-Health and Bioengineering Conference,,,,Romania Sect; Romania Sect EMB Chapter; IEEE,,,,,,,,,,"

3rd International Conference on E-Health and Bioengineering (EHB), Univ Med & Pharm, Iasi, ROMANIA, NOV 24-26, 2011

",,,System dynamics; 1; 410,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RQF4X6H9,conferencePaper,2011,"Taboada, Manel; Cabrera, Eduardo; Iglesias, Ma Luisa; Epelde, Francisco; Luque, Emilio",An Agent-Based Decision Support System for Hospitals Emergency Departments,PROCEEDINGS OF THE INTERNATIONAL CONFERENCE ON COMPUTATIONAL SCIENCE (ICCS),,,10.1016/j.procs.2011.04.203,,"Modeling and simulation have been shown to be useful tools in many areas of the Healthcare operational management, field in which there is probably no area more dynamic and complex than hospital emergency departments (ED). This paper presents the results of an ongoing project that is being carried out by the Research Group in Individual Oriented Modeling (IoM) of the University Autonoma of Barcelona (UAB) with the participation of Hospital of Sabadell ED Staff Team. Its general objective is creating a simulator that, used as decision support system (DSS), aids the heads of the ED to make the best informed decisions possible. The defined ED model is a pure Agent-Based Model, formed entirely of the rules governing the behavior of the individual agents which populate the system. Two distinct types of agents have been identified, active and passive. Active agents represent human actors, meanwhile passive agents represent services and other reactive systems. The actions of agents and the communication between them will be represented using Moore state machines extended to include probabilistic transitions. The model also includes the environment in which agents move and interact. With the aim of verifying the proposed model an initial simulation has been created using NetLogo, an agent-based simulation environment well suited for modeling complex systems.",2011,21/11/2018 11:00,14/04/2020 08:35,,1870-1879,,,4,,,,Procedia Computer Science,,,,"Elsevier; Univ Tsukuba, Ctr Computat Sci",,,,,,,,,,"

International Conference on Computational Science (ICCS) on the Ascent of Computational Excellence, Campus Nanyang Technolog Univ, Singapore, SINGAPORE, 2011

",,,00; 100,,"Sato, M and Matsuoka, S and Sloot, PMA and VanAlbada, GD and Dongarra, J",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2KENFQQM,conferencePaper,2011,"Taboada, Manel; Cabrera, Eduardo; Luque, Emilio",A Decision Support System for Hospital Emergency Departments Built Using Agent-Based Techniques,ADVANCES ON PRACTICAL APPLICATIONS OF AGENTS AND MULTI-AGENT SYSTEMS,978-3-642-19874-8,,10.1007/978-3-642-19875-5_32,,"This paper presents the results of an ongoing project that is being carried out by the Research Group in Individual Oriented Modelling (IoM) of the University Autonoma of Barcelona (UAB) with the participation of Hospital Emergency Department (ED) Staff Teams. Its general objective is creating a simulator that, used as decision support system (DSS), aids the heads of the ED to make the best informed decisions possible. The defined ED model is a pure Agent-Based Model, formed entirely of the rules governing the behaviour of the individual agents which populate the system. The actions of agents and the communication between them are represented using Moore state machines extended to include probabilistic transitions. The model also includes the environment in which agents move and interact. With the aim of verifying the proposed model an initial simulation has been created using NetLogo.",2011,21/11/2018 11:00,14/04/2020 08:35,,247-253,,,88,,,,Advances in Intelligent and Soft Computing,,,,,,,,,,,,,,"

9th International Conference on Practical Applications of Agents and Multi-Agent Systems, Univ Salamanca, Salamanca, SPAIN, APR 06-08, 2011

",,,1; Agent Based; 999,,"Demazeau, Y and Pechoucek, M and Corchado, JM and Bajo, J",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YEAR9QFB,conferencePaper,2011,"Diaz, Rafael; Tulpule, Mandar; Behr, Joshua G.",A SYSTEM DYNAMICS APPROACH TO MODELING THE COST ELEMENTS OF CHRONIC DISEASE MANAGEMENT INTERVENTIONS,"13RD INTERNATIONAL CONFERENCE ON HARBOR, MARITIME & MULTIMODAL LOGISTICS MODELING AND SIMULATION (HMS 2011)",978-88-903724-6-9,,,,"Medical treatment for chronic conditions forms a major portion of the US healthcare expenditure. Chronic diseases are generally associated with ailments without any permanent cure which significantly affect the health status, lifestyle, mobility and longevity of patients. A variety of chronic disease management interventions have been deployed to help patients better manage their medical condition. The main purpose of such interventions is to improve their health condition while achieving cost savings through a reduced healthcare utilization rate. While these interventions are desirable from the point of view of relevant clinical outcomes, the monetary outcomes in terms of costs and savings are uncertain. Further, most studies rely on short term savings and do not consider future healthcare costs. This study presents a system dynamics model representing the key cost factors involved in implementing a disease management intervention, and the dynamics associated with those factors. A simple goal seeking structure is embedded in the model as a simulation based optimization routine. The functionality of the model is demonstrated by means of hypothetical scenarios implemented via sensitivity analysis. The model provides useful insights into how the initial estimates of the cost of intervention and the resulting savings would change depending on the uncertainties, feedbacks and the targeted savings in the system. The model is designed to be used as a learning and decision support tool for implementing chronic disease management interventions.",2011,21/11/2018 11:00,14/04/2020 08:34,,197-204,,,,,,,,,,,"Univ Genoa, DIPTEM; Liophant Simulat; Simulat Team; Int Mediterranean & Latin Amer Council Simulat; Univ Calabria, Mech Dept; Lab enterprise Solut, Modeling & Simulat Ctr; Modeling & Simulat Ctr Excellence; Riga Tech Univ, Miss Latvian Ctr; Logism; Lab Sci Informat Syst; Univ Perugia, MISS; LAMCE COPPE UFRJ, MISS Brasilian Ctr; McLeod Inst Simulat Sci; McLeod Modeling & Simulat Network; Latvian Simulat Soc; Ecole Superiure Ingenierie Sci Appliquees; Fac Ciencias Exactas Ingn & Agrimensura; Univ La Laguna; CIFASIS CONICET UNR UPCAM; Inst Syst & Technologies Informat, Control & Commun; Presagis; CAE; CAL TEK; MAST; Aegis Technologies",,,,,,,,,,"

13th International Conference on Harbor, Maritime and Multimodal Logistics Modeling and Simulation (HMS), Rome, ITALY, SEP 12-14, 2011

",,,System dynamics; 1; 310,,"Bruzzone, A and Longo, F and Merkuryev, Y and Piera, MA",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, H829AGC5,conferencePaper,2011,"Taboada, Manel; Cabrera, Eduardo; Luque, Emilio",AN AGENT-BASED DECISION SUPPORT SYSTEM FOR HOSPITAL EMERGENCY DEPARTMENTS,HEALTHINF 2011: PROCEEDINGS OF THE INTERNATIONAL CONFERENCE ON HEALTH INFORMATICS,978-989-8425-34-8,,,,"Healthcare operational management provides many areas where modelling and simulation have been shown to be useful tools, and within this field there is probably no area more fluid or dynamic than hospital emergency departments (ED). This paper presents the results of an ongoing project that is being carried out by Individual Oriented Modelling (IoM) research group of the UAB, with the participation of Hospital ED Staff Teams. The general objective is creating a simulator that, used as decision support system (DSS), aids the heads of the ED to answer both, “what if ... “ questions in order to make the best informed decisions possible, and more complex questions involving the optimisation of the system. The defined ED model is a pure Agent-Based Model, formed entirely of the rules governing the behaviour of the individual agents which populate the system. Two distinct types of agents have been identified, active and passive. Active agents represent human actors, meanwhile passive agents represent services and other reactive systems. Active agents are described by Moore state machines extended to include probabilistic transitions. With the aim of verifying the proposed model a simulation has been created using NetLogo.",2011,21/11/2018 11:00,14/04/2020 08:35,,417-422,,,,,,,,,,,"Inst Syst & Technol Informat, Control & Comm; IEEE, Engn Med & Biol Soc; IEEE, Portugal EMBS Chapter; European Soc Engn & Med; Biomed Engn Soc",,,,,,,,,,"

4th International Conference on Health Informatics (HEALTHINF 2011), Rome, ITALY, JAN 26-29, 2011

",,,00; 110,,"Traver, V and Fred, A and Filipe, J and Gamboa, H",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, H5KEWUZV,journalArticle,2010,"Latkin, Carl; Weeks, Margaret R.; Glasman, Laura; Galletly, Carol; Albarracin, Dolores",A Dynamic Social Systems Model for Considering Structural Factors in HIV Prevention and Detection,AIDS AND BEHAVIOR,,1090-7165,10.1007/s10461-010-9804-y,,"We present a model for HIV-related behaviors that emphasizes the dynamic and social nature of the structural factors that influence HIV prevention and detection. Key structural dimensions of the model include resources, science and technology, formal social control, informal social influences and control, social interconnectedness, and settings. These six dimensions can be conceptualized on macro, meso, and micro levels. Given the inherent complexity of structural factors and their interrelatedness, HIV prevention interventions may focus on different levels and dimensions. We employ a systems perspective to describe the interconnected and dynamic processes of change among social systems and their components. The topics of HIV testing and safer injection facilities (SIFs) are analyzed using this structural framework. Finally, we discuss methodological issues in the development and evaluation of structural interventions for HIV prevention and detection.",2010-12,21/11/2018 11:00,14/04/2020 08:34,,S222-S238,,2,14,,,,,,,,,,,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FA8UB79Y,journalArticle,2010,"Lloyd-Puryear, Michele A.; Brower, Amy",Long-term follow-up in newborn screening: A systems approach for improving health outcomes,GENETICS IN MEDICINE,,1098-3600,10.1097/GIM.0b013e3181fe5d9c,,"Background: Newborn screening is a complex system of interrelated multidimensional components singly focused on safeguarding the health of our nation's newborns. The long-term health outcome and well-being of individuals identified by newborn screening represents a meaningful measurement of the performance of the newborn screening system. This assessment of long-term follow-up requires a systems approach that connects `stakeholders, processes, and outcomes through the collection, integration, evaluation, and sharing of key data and metrics. Methods: A review of the principles of a systems approach and its application to newborn screening long-term follow-up was performed. Past and current efforts by HRSA/MCHB that address individual components of newborn screening were assessed and utilized to outline lessons learned and suggest next steps. Results: The principle features of a systems approach applied to the creation and utilization of a health information exchange system for the long-term follow up of screen positive patients is defined. The application of this approach is in progress through the HRSA/MCHB's Effective Follow-up in Newborn Screening project. Conclusions: While several elements are in place to realize a systems approach, the authors think that the key is an integrated, multidirectional health information exchange system that functions locally, regionally and nationally, and enables information exchange between private and public health sectors. Genet Med 2010:12(12):S256-S260.",2010-12,21/11/2018 11:00,14/04/2020 08:34,,S256-S260,,"12, S",12,,,,,,,,,,,,,,,,,,,,,"Humans; Delivery of Health Care/*standards; Program Evaluation; United States; Young Adult; Follow-Up Studies; Child; Adolescent; Child, Preschool; Infant; *Neonatal Screening; Infant, Newborn; Cooperative Behavior; Information Dissemination; *Outcome Assessment (Health Care); Quality Assurance, Health Care; Information Systems; 00; Advisory Committees; Consensus; Metabolic Diseases/*diagnosis/genetics/prevention & control; State Health Plans; United States Health Resources and Services Administration; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, L5LJA7AY,journalArticle,2010,"Cochran, Jeffery K.; Broyles, James R.",Developing nonlinear queuing regressions to increase emergency department patient safety: Approximating reneging with balking,COMPUTERS & INDUSTRIAL ENGINEERING,,0360-8352,10.1016/j.cie.2010.05.010,,"Administrators know when Emergency Department (ED) overcrowding is a problem in their hospital. Lead times to change ED capacity are long and require strategic tools. ED patients who Leave WithOut Treatment (LWOT) before seeing a physician are, in queuing nomenclature, `reneging' from an overcrowded situation and are an important measure of ED patient safety. We propose to enable strategic decision making on future ED capacity on the basis of patient safety (rather than congestion measures). We hypothesize that the LWOT reneging percentage is captured by the balking probability (p(K)) relationship of an M/M/1/K queue. If true, this relationship is superior to the typical ad hoc regression relationships commonly found. Since it is based on a physical scientific mechanism, the sample size requirements and extrapolation power are improved. We derive the form of a binomial response nonlinear weighted regression model that best fits pK for predicting LWOT to long-term ED performance by means of Gauss-Newton linearization. Our results include asymptotic Wald confidence intervals on prediction, specific Pearson and Deviance model goodness-of-fit tests, and residual analysis that facilitate identification of outlying data points. None of these features exist for reneging (or balking) models previously presented in the literature. (C) 2010 Elsevier Ltd. All rights reserved.",2010-10,21/11/2018 11:00,14/04/2020 08:34,,378-386,,3,59,,,,,,,,,,,,,,,,,,,,,1; Queueing; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, G3FKW4IB,journalArticle,2010,"Burtnyk, Mathieu; Chopra, Rajiv; Bronskill, Michael",Simulation study on the heating of the surrounding anatomy during transurethral ultrasound prostate therapy: A 3D theoretical analysis of patient safety,MEDICAL PHYSICS,,0094-2405,10.1118/1.3426313,,"Purpose: MRI-guided transurethral ultrasound therapy can generate highly accurate volumes of thermal coagulation conforming to 3D human prostate geometries. This work simulated, quantified, and evaluated the thermal impact of these treatments on the rectum, pelvic bone, neurovascular bundles (NVBs), and urinary sphincters because damage to these structures can lead to complications. Methods: Twenty 3D anatomical models of prostate cancer patients were used with detailed bioacoustic simulations incorporating an active feedback algorithm which controlled a rotating, planar ultrasound transducer (17, 4 x 3 mm(2) elements, 10 W-acoustic/cm(2)). Heating of the adjacent surrounding anatomy was evaluated at 4.7, 9.7, and 14.2 MHz using thermal tolerances reported in literature. Results: Heating of the rectum posed the most important safety concern, influenced largely by the water temperature of an endorectal cooling device (ECD); depending on anatomy, temperatures of 7-37 degrees C were required to limit potential damage to less than 10 mm(3) on the outer 1 mm layer of the rectal wall. Heating of the pelvic bone could be important at 4.7 MHz. A smaller sized ECD or a higher ultrasound frequency in sectors where the bone was less than 10 mm from the prostate reduced heating in all cases below the threshold for irreversible damage. Heating of the NVB was significant in 75% of the patient models in the absence of treatment planning; this proportion was reduced to 5% by increasing treatment margins up to 4 mm. To avoid damaging the urinary sphincters, the transducer should be positioned at least 2-4 mm from the sphincters, depending on the transurethral cooling temperature. Conclusions: Simulations show that MRI-guided transurethral therapy can treat the prostate accurately, but in the absence of treatment planning, some thermal impact can be predicted on the surrounding anatomy. Treatment planning strategies have been developed, which reduce thermal injury to the surrounding anatomy. (C) 2010 American Association of Physicists in Medicine. [DOI: 10.1118/1.3426313]",2010-06,21/11/2018 11:00,14/04/2020 08:34,,2862-2875,,6,37,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EVCMWRJ7,journalArticle,2010,"Dormandy, E.; Bryan, S.; Gulliford, M. C.; Roberts, T. E.; Ades, A. E.; Calnan, M.; Atkin, K.; Karnon, J.; Barton, P. M.; Logan, J.; Kavalier, F.; Harris, H. J.; Johnston, T. A.; Anionwu, E. N.; Davis, V.; Brown, K.; Juarez-Garcia, A.; Tsianakas, V.; Marteau, T. M.",Antenatal screening for haemoglobinopathies in primary care: a cohort study and cluster randomised trial to inform a simulation model. The Screening for Haemoglobinopathies in First Trimester (SHIFT) trial,HEALTH TECHNOLOGY ASSESSMENT,,1366-5278,10.3310/htal4200,,"Objectives: To assess the effectiveness, cost-effectiveness, acceptability and feasibility of offering universal antenatal sickle cell and thalassaemia (SCT) screening in primary care when pregnancy is first confirmed and to model the cost-effectiveness of early screening in primary care versus standard care. Design: A population-based cohort study, cluster randomised trial and refinement of a published decision model. Setting: Twenty-five general practices from two UK primary care trusts (PCTs) in two inner city boroughs with a high proportion of residents from minority ethnic groups. Participants: Practices were considered eligible if they agreed to be randomised and they were able to provide anonymous data on all eligible pregnant women. Participants were at least 18 years old and consented to take part in the evaluation. Interventions: Practices were allocated to intervention, using minimisation and stratifying for PCT and number of partners at the practice, as follows: screening in primary care with parallel father testing (test offered to mother and father simultaneously; n=8 clusters, 1010 participants); screening in primary care with sequential father testing (test offered to father only if mother identified as carrier; n=9 clusters, 792 participants); and screening in secondary care with sequential father testing (standard care; n=8 clusters, 619 participants). Main outcome measures: Data on gestational age at pregnancy confirmation and screening date were collected from trial practices for 6 months before randomisation in the cohort phase. The primary outcome measure was timing of SCT screening, measured as the proportion of women screened before 70 days' (10 weeks') gestation. Other outcomes included: offer of screening, rates of informed choice and proportion of women who knew the carrier status of their baby's father by 77 days (11 weeks). Results: For 1441 eligible women in the cohort phase, the median [interquartile range (IQR)] gestational age at pregnancy confirmation was 7.6 weeks (6.0 to 10.7 weeks) and 74% presented in primary care before 10 weeks.The median gestational age at screening was 15.3 weeks (IQR 12.6 to 18.0 weeks). Only 4.4% were screened before 10 weeks.The median delay between pregnancy confirmation and screening was 6.9 weeks (4.7 to 9.3 weeks). In the intervention phase, 1708 pregnancies from 25 practices were assessed for the primary outcome measure. Completed questionnaires were obtained from 464 women who met eligibility criteria for the main analysis.The proportion of women screened by 10 weeks (70 days) was 9/441(2%) in standard care, compared with 161/677 (24%) in primary care with parallel testing, and 167/590 (28%) in primary care with sequential testing. The proportion of women offered screening by 10 weeks (70 days) was 3/90 (3%) in standard care (note offer of test ascertained for questionnaire respondents only), compared with 321/677 (47%) in primary care with parallel testing, and 281/590 (48%) in primary care with sequential testing. The proportion of women screened by 26 weeks (182 days) was similar across the three groups: 324/441 (73%) in standard care, 571/677 (84%, 0.09) in primary care with parallel testing, and 481/590 (82%, 0.148) in primary care with sequential testing. The screening uptake of fathers was 51/677 (8%) in primary care with parallel testing, and 16/590 (3%) in primary care with sequential testing, and 13/441(3%) in standard care.The predicted average total cost per pregnancy of offering antenatal SCT screening was estimated to be 13 in standard care, 18.50 in primary care with parallel testing, and 16.40 in primary care with sequential testing. The incremental cost-effectiveness ratio (ICER) was 23 in primary care with parallel testing and LI 2 in primary care with sequential testing when compared with standard care.Women offered testing in primary care were as likely to make an informed choice as those offered screening by midwives later in pregnancy, but less than one-third of women overall made an informed choice about screening. Conclusions: Offering antenatal SCT screening as part of pregnancy-confirmation consultations significantly increased the proportion of women screened before 10 weeks (70 days), from 2% in standard care to between 16% and 27% in primary care, but additional resources may be required to implement this.There was no evidence to support offering fathers screening at the same time as women.",2010-04,21/11/2018 11:00,14/04/2020 08:34,,1+,,20,14,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KATRUGER,journalArticle,2010,"Tarride Fernandez, Mario Ivan; Vasquez, Oscar C.; Gonzalez Martinic, Julia",Computer modeling and simulation of the patient-visit network within a Chilean public health service,REVISTA PANAMERICANA DE SALUD PUBLICA-PAN AMERICAN JOURNAL OF PUBLIC HEALTH,,1020-4989,10.1590/S1020-49892010000300007,,"Objective. To create a computerized model and simulation of the patient visit/referrals process for a health care services organization within Chile's public health care system. Methods. The study was performed with a “system dynamics” focus. Data were collected from the health care service centers, and a referrals model was created. Specialty areas to be modeled were chosen based on the length of their waiting times. Equations were defined for calculating care visits, referrals, and waiting times. Databases were designed and populated with centers' data. The model was programmed and validated through comparisons with actual data. Scenarios were simulated that would reduce patient waiting time by increasing staff hours or improving diagnostic resolution at the primary care and specialty centers, or both. Results. The modeling included 22 centers, 1 451 referral flows, and 12 medical specialty areas, in addition to general medicine. A total of 686 869 registered office visits, referrals, and waiting logs were processed. The validation yielded high determinant coefficients and a 10.43% percentage error regarding actual waiting time logs. Conclusions. This methodology proved to be useful for modeling a health care network. An auto-referral process was observed where options were available, with opportunities for improvement in diagnostic resolution at the primary health care centers, as well as at the specialty centers. Moderate increases in diagnostic accuracy and office hours would completely eliminate waiting times at the specialty centers.",2010-03,21/11/2018 11:00,14/04/2020 08:34,,203-210,,3,27,,,,,,,,,,,,,,,,,,,,,Humans; Public Sector; Primary Health Care; *Computer Simulation; Computer Simulation; Process Assessment (Health Care); Chile; Public Health Administration; 1; Descriptive Statistics; Human; Health Services; *Health Services Administration; Review,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KA8KTBXY,conferencePaper,2010,"Bashash, Saeid; Moura, Scott J.; Fathy, Hosam K.",Charge Trajectory Optimization of Plug-in Hybrid Electric Vehicles for Energy Cost Reduction and Battery Health Enhancement,2010 AMERICAN CONTROL CONFERENCE,978-1-4244-7427-1,,,,"This paper examines the problem of optimizing the charge trajectory of a plug-in hybrid electric vehicle (PHEV), defined as the timing and rate with which the PHEV obtains electricity from the power grid. Two objectives are considered in this optimization. First, we minimize the total cost of fuel and electricity consumed by the PHEV over a 24-hour naturalistic drive cycle. We predict this cost using a previously-developed stochastic optimal PHEV power management strategy. Second, we also minimize total battery health degradation over the course of the 24-hour cycle. This degradation is predicted using an electrochemistry-based model of anode-side resistive film formation in Li-ion batteries. The paper shows that these two objectives are conflicting, and trades them off using a non-dominated sort genetic algorithm, NSGA-II. As a result, a Pareto front of optimal PHEV charge trajectories is obtained. The effects of electricity price and trip schedule on the Pareto front are analyzed and discussed.",2010,21/11/2018 11:00,14/04/2020 08:34,,5824-5831,,,,,,,Proceedings of the American Control Conference,,,,,,,,,,,,,,"

American Control Conference, Baltimore, MD, JUN 30-JUL 02, 2010

",,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IY4VTP2J,conferencePaper,2010,"Bhandari, Gokul; Snowdon, Anne",Symbiotic Simulation Decision Support System for Injury Prevention,ADVANCES IN IN℡LIGENT DECISION TECHNOLOGIES,978-3-642-14615-2,,,,"Symbiotic simulation decision support systems refer to a class of decision support systems in which there is a presence of beneficial feedback between a physical system and a simulation system. In this paper, we report the design and development of such a system in the area of injury prevention. Specifically, we used our decision support system to lower the occurrences of patient falls in hospitals and to minimize injury and death due to the improper use of child safety seats in vehicles. Empirical results from our study show a great potential of our DSS for assisting decision makers and stakeholders in the healthcare sector.",2010,21/11/2018 11:00,14/04/2020 08:34,,373-382,,,4,,,,Smart Innovation Systems and Technologies,,,,"Loyola Univ, Sellinger Sch Business & Management; KES Int",,,,,,,,,,"

2nd International Symposium on Intelligent Decision Technologies, Loyola Univ, Baltimore, MD, JUL 28-30, 2010

",,,00; 110,,"PhillipsWren, G and Jain, LC and Nakamatsu, K and Howlett, RJ",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, SPSQ5EQF,journalArticle,2010,"Sanchez Santos, L.; Rodriguez Nunez, A.; Iglesias Vazquez, J. A.; Civantos Fuentes, E.; Couceiro Gianzo, J.; Rodriguez Suarez, J.; Fernandez Sanmartin, M.",Advanced simulation for primary care paediatricians. Development of an itinerant program and opinions of participants,ANALES DE PEDIATRIA,,1695-4033,10.1016/j.anpedi.2009.08.017,,"Introduction and objectives: Advanced simulation (AS) is a teaching methodology that has shown to be useful for training health staff at hospital level; however, its application in primary care paediatrics is very limited. Our objective was the development of an AS project focused on the learning needs of the primary care paediatricians, as well as to know the participants' opinions as one of the elements to assess its appropriateness. Material and methods: Phase 1: A multidisciplinary working group was organized and sponsored by the SEPEAP to design and put the course into practice. Phase 2: Itinerant courses were carried out in several cities in Spain. At the end of each course, a survey was carried out that was focused on motivation aspects, pertinence of contents and methodology. Each item was scored on a numerical scale from 0 (very bad) to 10 (very good). Study period: May 2008 to May 2009. Results: After analysing the potential learning needs of target population, available time, teaching material available and methodology of simulation and debriefing, a course model was designed and the cases were programmed. Twelve courses were carried out in 12 cities. The total number of participants was 186; of them, 177 (95.2%) answered the survey. Mean +/- SD scores for main items were: organization (9.23 +/- 0.50), objectives related to prior expectation (9.29 +/- 0.43), usefulness of course program to work activity (9.42 +/- 0.43), cases that resemble reality (9.18 +/- 0.42) and good instructors-participants relationship (9.68 +/- 0.20). Conclusions: The AS course for primary care paediatrics, with the proposed format, is feasible and well adapted to the needs of the target population. Primary care paediatricians consider this type of teaching and learning activity as a useful tool. for their continuing education and for improving their professional abilities. (C) 2009 Asociacion Espanola de Pediatria. Published by Elsevier Espana, S.L. All rights reserved.",2010-01,21/11/2018 11:00,14/04/2020 08:35,,55-61,,1,72,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8AZEPF5C,journalArticle,2010,"McEwan, Phil; Bergenheim, Klas; Yuan, Yong; Tetlow, Anthony P.; Gordon, Jason P.",Assessing the Relationship between Computational Speed and Precision A Case Study Comparing an Interpreted versus Compiled Programming Language using a Stochastic Simulation Model in Diabetes Care,PHARMACOECONOMICS,,1170-7690,10.2165/11535350-000000000-00000,,"Background: Simulation techniques are well suited to modelling diseases yet can be computationally intensive. This study explores the relationship between modelled effect size, statistical precision, and efficiency gains achieved using variance reduction and an executable programming language. Methods: A published simulation model designed to model a population with type 2 diabetes mellitus based on the UKPDS 68 outcomes equations was coded in both Visual Basic for Applications (VBA) and C++. Efficiency gains due to the programming language were evaluated, as was the impact of antithetic variates to reduce variance, using predicted QALYs over a 40-year time horizon. Results: The use of C++ provided a 75- and 90-fold reduction in simulation run time when using mean and sampled input values, respectively. For a series of 50 one-way sensitivity analyses, this would yield a total run time of 2 minutes when using C++, compared with 155 minutes for VBA when using mean input values. The use of antithetic variates typically resulted in a 53% reduction in the number of simulation replications and run time required. When drawing all input values to the model from distributions, the use of C++ and variance reduction resulted in a 246-fold improvement in computation time compared with VBA - for which the evaluation of 50 scenarios would correspondingly require 3.8 hours (C++) and approximately 14.5 days (VBA). Conclusions: The choice of programming language used in an economic model, as well as the methods for improving precision of model output can have profound effects on computation time. When constructing complex models, more computationally efficient approaches such as C++ and variance reduction should be considered; concerns regarding model transparency using compiled languages are best addressed via thorough documentation and model validation.",2010,21/11/2018 11:00,14/04/2020 08:34,,665-674,,8,28,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ALSE6VWA,journalArticle,2009,"Pian-Smith, May C. M.; Simon, Robert; Minehart, Rebecca D.; Podraza, Marjorie; Rudolph, Jenny; Walzer, Toni; Raemer, Daniel",Teaching Residents the Two-Challenge Rule: A Simulation-Based Approach to Improve Education and Patient Safety,SIMULATION IN HEALTHCARE,,1559-2332,10.1097/SIH.0b013e31818cffd3,,"Introduction: Residents train in a historically hierarchical system. They may be compelled to question their teachers if they do not understand or disagree with a clinical decision, have a patient safety concern, or when treatment plans are unclear. We sought to determine whether a debriefing intervention that emphasizes (1) joint responsibility for safety and (2) the “two-challenge rule” (a rubric for challenging others) using a conversational technique that is assertive and collaborative (advocacy-inquiry) can improve the frequency and effectiveness with which residents “speak up” to superiors. Methods: In a simulated operating room, anesthesiology trainees were presented with opportunities to challenge coworkers (eg, orders to administer a relatively contraindicated medication). Opportunities to challenge the attending faculty anesthesiologist, attending faculty surgeon, and nurse (all confederates) were presented. When debriefed, subjects were taught the two-challenge rule and a communication technique that paired advocacy (stating trainee's observation) and inquiry (request for the other's reasoning). A second scenario offered new opportunities to challenge. Video recorded scenarios were evaluated by two investigators and trainee use of the prescribed advocacy-inquiry language was rated on a 5-point scale. Results: Forty subjects participated. Overall use of the two-challenge rule and advocacy-inquiry increased after debriefing. The debriefing and instruction specifically improved the frequency and quality of challenges directed toward superordinate physicians, without improving resident challenges toward nurses. Conclusions: This instructional intervention improves “speaking up” by residents to other physicians during simulated obstetric cases. Providing increased opportunities for resident learning, sharing responsibility for patient safety, and overcoming communication barriers within the medical hierarchy may improve teamwork and patient safety. (Sim Healthcare 4: 84-91, 2009)",2009,21/11/2018 11:00,14/04/2020 08:35,,84-91,,2,4,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NI97CRF9,journalArticle,2009,"Mullens, Wilfried; Grimm, Richard A.; Verga, Tanya; Dresing, Thomas; Starling, Randall C.; Wilkoff, Bruce L.; Tang, W. H. Wilson",Insights From a Cardiac Resynchronization Optimization Clinic as Part of a Heart Failure Disease Management Program,JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY,,0735-1097,10.1016/j.jacc.2008.11.024,,"Objectives Our aim was to determine the feasibility and value of a protocol-driven approach to patients with cardiac resynchronization therapy (CRT) who did not exhibit a positive response long after implant. Background Up to one-third of patients with advanced heart failure do not exhibit a positive response to CRT. Methods A total of 75 consecutive ambulatory patients with persistent advanced heart failure symptoms and/or adverse reverse remodeling and CRT implanted >6 months underwent a comprehensive protocol-driven evaluation to determine the potential reasons for a suboptimal response. Recommendations were made to maximize the potential of CRT, and adverse events were documented. Results All patients ( mean left ventricular [LV] ejection fraction 23 +/- 9%, LV end-diastolic volume 275 +/- 127 ml) underwent evaluation. Eighty-eight percent of patients had significantly better echocardiographic indexes of LV filling and LV ejection with optimal setting of their CRT compared with a temporary VVI back-up setting. Most patients had identifiable reasons for suboptimal response, including inadequate device settings (47%), suboptimal medical treatment (32%), arrhythmias ( 32%), inappropriate lead position (21%), or lack of baseline dyssynchrony ( 9%). Multidisciplinary recommendations led to changes in device settings and/or other therapy modifications in 74% of patients and were associated with fewer adverse events (13% vs. 50%, odds ratio: 0.2 [95% confidence interval: 0.07 to 0.56], p = 0.002) compared with those in which no recommendation could be made. Conclusions Routine protocol-driven approach to evaluate ambulatory CRT patients who did not exhibit a positive response is feasible, and changes in device settings and/or other therapies after multidisciplinary evaluation may be associated with fewer adverse events. (J Am Coll Cardiol 2009; 53: 765-73) (C) 2009 by the American College of Cardiology Foundation",03/03/2009,21/11/2018 11:00,14/04/2020 08:35,,765-773,,9,53,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UZGQHG9I,journalArticle,2009,"Sokolova, Marina V.; Fernandez-Caballero, Antonio",Modeling and implementing an agent-based environmental health impact decision support system,EXPERT SYSTEMS WITH APPLICATIONS,,0957-4174,10.1016/j.eswa.2008.01.041,,"This paper presents all approach to the creation of an agent-based system for the assessment of environmental impact upon human health. As indicators of the environmental impact water pollution, indexes of traffic and industrial activity, wastes and solar radiation are assumed. And as human health indicator morbidity is taken. All the data comprise multiple heterogeneous data repositories. The system is logically and functionally divided into three layers, solving the tasks of information fusion, pattern discovery and decision support making, respectively. The outcomes of the system design phase under Prometheus methodology and the complete characteristics of the agents forming the proposal are discussed. The discovered patterns are used as a foundation for real-time decision making, which is of great importance for adequate and effective management by responsible governmental authorities. (C) 2008 Elsevier Ltd. All rights reserved.",2009-03,21/11/2018 11:00,14/04/2020 08:35,,2603-2614,,2,36,,,,,,,,,,,,,,,,,,,,,1; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PWV5A2CT,journalArticle,2009,"Kara, Ahmet",An applied stochastic model of the quality-quantity trade-off in the public health care sector,QUALITY & QUANTITY,,0033-5177,10.1007/s11135-007-9106-2,,"It is a striking feature of the many of the developing country public service sectors that the sectors in question often overproduce the quantity of services but underproduce the quality. This feature, which is exemplified in this paper, is rooted in a wide spectrum of economic and sociological factors ranging from the economic and sociological profile of the service receiving people to the asymmetric density of service-receiving population across their regions. This feature, we conjecture, is a source of a considerable degree of suboptimality in some of the developing countries. If our conjecture is correct, correcting such suboptimalities is likely to yield significant welfare improvements that could help speed up the process of development in the underdeveloped regions of the world. To analyze the supoopimalites in question, we will first develop a concept (and a model) of optimal quality in the public service sector, which indicates the level of quality that maximizes expected public satisfaction subject to available resources. Resources are used in an efficient manner to produce the service in question. The concept and the model in the paper make a needed contribution to the quality discourse by presenting a way of determining the quality improvements (or adjustments) necessary to achieve optimum in the public service sector. The paper presents an application (a case study) of this new concept in the public healthcare sector in Turkey, and explores the differences between the actual and optimal quality in the sector in question. It turns out that there is a considerable difference between the actual and optimal levels of quality (as well as those of quantity) in the Turkish public healthcare sector in an overpopulated city (Istanbul), indicating a significant overproduction of quantity and underproduction of quality. Thus, to achieve the optimal levels, the sector should increase quality and reduce quantity by a considerable margin. The quantified differences (gaps) between actual and optimal levels point out a considerable room for welfare improvement. Optimum-seeking adjustments closing these gaps could be shown to lead to considerable satisfaction and welfare gains, the measurement of which is worthy of future research.",2009-03,21/11/2018 11:00,14/04/2020 08:34,,277-289,,2,43,,,,,,,,,,,,,,,,,,,,,1; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, SEQM2IA4,conferencePaper,2009,"Bosansky, Branislav; Lhotska, Lenka",Agent-Based Process-Critiquing Decision Support System,2009 2ND INTERNATIONAL SYMPOSIUM ON APPLIED SCIENCES IN BIOMEDICAL AND COMMUNICATION TECHNOLOGIES (ISABEL 2009),978-1-4244-4640-7,,,,"Formalization of the work practice using processes is a widely used method throughout various fields of industry. However, their application within the healthcare domain is rather unsuccessful due to the need for high agility, exceptions handling, and for working with complex medical knowledge that affects these processes. To overcome these problems the agent paradigm and multi-agent systems can be applied. In this paper we present a novel architecture of a multi-agent system that is able to work with general processes. As an exemplary application of the architecture we describe a critiquing decision support system for healthcare specialists based on formalized medical guidelines.",2009,21/11/2018 11:00,14/04/2020 08:34,,101+,,,,,,,,,,,,,,,,,,,,,"

2nd International Symposium on Applied Sciences in Biomedical and Communication Technologies, Bratislava, SLOVAKIA, NOV 24-27, 2009

",,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, M9IYBCQR,conferencePaper,2009,"Aspergh, Giada; Facchin, Paola; Ferrante, Anna; Dalla Pozza, Laura Visona; Romanin-Jacur, Giorgio",PAEDIATRIC PALLIATIVE CARE PLANNING: MODELS AND SIMULATION,7TH INDUSTRIAL SIMULATION CONFERENCE 2009,978-90-77381-48-9,,,,"Paediatric palliative patients are children suffering for incurable pathologies which cause them a lot of human, clinical, psychological, ethical and spiritual problems and require special assistance. Only in recent times they have been considered as specific patients needing qualified cares. In this paper we have built up a simulation model describing paediatric palliative patients movements among the interested health facilities, more precisely hospital departments, hospice, integral home care and simple home care, and the interactions of such patients with ordinary patients in seizing places in hospital departments. The model, implemented on a personal computer by means of a specific simulation language, permits to evidence the lacks of the existing assistance network and to suggest suitable adaptations. The model has been usefully applied to Veneto region in North-East Italy.",2009,21/11/2018 11:00,14/04/2020 08:34,,214+,,,,,,,,,,,ETI; Loughborough Univ; I Chem; EUROSIS; AEKI; CREAX; ENSAIT; Ghent Univ; UPV,,,,,,,,,,"

7th International Industrial Simulation Conference, Loughborough, ENGLAND, JUN 01-03, 2009

",,,1; 110,,"Das, DB and Nassehi, V and Deka, L",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2E2P43S8,conferencePaper,2009,"Altmann, J.; Franz, B.; Moertenschlag, D.; Pfeifer, F.; Strasser, M.; Aichinger, B.; Koller, R.",IHEXPLORER: VISUALIZATION AND ANALYSIS OPTIMIZATION OF HEALTH SYSTEM INTEGRATION,EHEALTH2009 - MEDICAL INFORMATICS MEETS EHEALTH,978-3-85403-250-2,,,,,2009,21/11/2018 11:00,14/04/2020 08:34,,115-121,,,,,,,,,,,Austria Comp Soc,,,,,,,,,,"

Conference on eHealth2009/eHealth Benchmarking, Vienna, AUSTRIA, MAY 07-08, 2009

",,,00; 110,,"Schreier, G and Hayn, D and Ammenwerth, E",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, G3RNLDWP,conferencePaper,2009,"Papadimitriou, Costas; Ntotsios, Evaggelos",Optimization Algorithms for System Integration,EMBODING IN℡LIGENCE IN STRUCTURES AND INTEGRATED SYSTEMS,978-3-908158-22-6,,,,"This work outlines the optimization algorithms involved in integrating system analysis and measured data collected from a network of sensors. The integration is required for structural health monitoring problems arising in structural dynamics and related to (1) model parameter estimation used for finite element model updating, (2) model-based damage detection in structures and (3) optimal sensor location for parameter estimation and damage detection. These problems are formulated as single- and multi-objective optimization problems of continuous or discrete-valued variables. Gradient-based, evolutionary, hybrid and heuristic algorithms are presented that effectively address issues related to the estimation of multiple local/global solutions and computational complexity arising in single and multi-objective optimization involving. continuous and discrete variables.",2009,21/11/2018 11:00,14/04/2020 08:35,,514-523,,,56,,,,Advances in Science and Technology,,,,,,,,,,,,,,"

3rd International Conference on Smart Materials, Structures and Systems, Acireale, ITALY, JUN 08-13, 2008

",,,00; 100,,"Vincenzini, P and Casciati, F",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8S7WJNGB,conferencePaper,2009,"Housseman, Sylvain; Absi, Nabil; Dauzere-Peres, Stephane; Chabannon, Christian; Hofman, Paul",SIMULATION AS A DECISION SUPPORT TOOL Estimating the Impacts of using RFID Technologies within Biobanks,HEALTHINF 2009: PROCEEDINGS OF THE INTERNATIONAL CONFERENCE ON HEALTH INFORMATICS,978-989-8111-63-0,,,,"The costs and benefits of introducing auto-identification are difficult to evaluate. The Return On Investment (ROI) may be calculated on manufacturing environments but in some service providing systems, like hospitals, it may be very hard and inaccurate to judge the relevance of a new configuration only through financial considerations. New information and communication technologies and devices appear rapidly. This study aims at quantifying the benefits of introducing new devices at different levels in a complex socio-technical system: a biobank (storage, transformation and exchanges of biological samples) using a discrete event dynamic systems simulation model as a quality measurement tool. After introducing the context, we will describe pertinent measurement possibilities adapted to the Supply Chain for Health services, and particularly to biobanks, and the way we implemented the simulation model used to get the results summarized in the last section, before concluding. The originalities of this paper are the process modeling, designed to be easily modified to test many different configurations and scenarios, and the quality indicators that are particularly adapted to health services.",2009,21/11/2018 11:00,14/04/2020 08:34,,337+,,,,,,,,,,,"Inst Syst & Technologies Informat, Control & Commun; IEEE Engn Med & Biol Soc; Workflow Management Coalit; Assoc Advancement Artificial Intelligence",,,,,,,,,,"

2nd International Conference on Health Informatics (HEALTHINF 2009), Oporto, PORTUGAL, JAN 14-17, 2009

",,,00; 100,,"Azevedo, L and Londral, AR",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8H9SDZY8,journalArticle,2009,"Eveborn, Patrik; Ronnqvist, Mikael; Einarsdottir, Helga; Eklund, Mats; Liden, Karin; Almroth, Marie",Operations Research Improves Quality and Efficiency in Home Care,INTERFACES,,0092-2102,10.1287/inte.1080.0411,,"Elder care systems are facing increased costs, primarily because the elderly constitute a growing percentage of the population. Sweden publicly finances such systems; in 2005, the cost to taxpayers on a national level was 8.8 billion euros ($13 billion). The many customized aspects of scheduling home care workers to assist elderly and disabled citizens with their varying needs contribute to these costs. Laps Care, a system that was developed in 2002, uses operations research modeling to eliminate the manual planning of home care unit assignments. More than 200 units/organizations in Swedish municipalities use Laps Care each day to plan staff scheduling and routing for 4,000 home care workers. The system has increased operational efficiency by 10-15 percent; this corresponds to an annual savings of 20-30 million euros ($30-$45 million). In addition, the quality of home care for elderly citizens has improved. The City of Stockholm, with its 800,000 inhabitants, adopted Laps Care in 2006 and started a full implementation and rollout during 2008, thus adding 800 units and 15,000 home care workers to the system. The savings for the City of Stockholm will be 20-30 million euros ($30-$45 million).",2009-02,21/11/2018 11:00,14/04/2020 08:34,,18-34,,1,39,,,,,,,,,,,,,,,,,,"

INFORMS Practice Conference, Baltimore, MD, APR 14, 2008

",,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ISDZCQ9R,journalArticle,2009,"Pacileo, Guglielmo; Fattore, Giovanni",Alcohol abuse prevention in young people: An economic simulation,JOURNAL OF SUBSTANCE USE,,1465-9891,10.3109/14659890802695865,,"Severe alcohol abuse can lead to death and disability. A large number of educational programmes for young people's drinking behaviour have been developed to counteract alcohol abuse. The aim of this research was to assess whether those programmes are rational from an economic point of view. It relies on a systematic review of economic evaluation analysis providing evidence on the status of those programmes. Only one study met all the inclusion criteria. This result suggested the performance of an economic evaluation of secondary data. A second systematic literature review with different inclusion criteria was therefore carried out. Nine studies met the inclusion criteria, but only three provided evidence of effectiveness. According to our simulations, if the interventions are effective they are also cost-effective. In other words if they can provide evidence of a decrease in alcohol use and abuse they can also provide evidence that the interventions are rational from an economic point of view. The review suggests two final comments. First, the current investment in preventive programmes is very limited. Secondly, larger studies and more adequate systems of evaluation are needed to provide scientific evidence of the impact of preventive educational strategies on alcohol abuse in young people.",2009,21/11/2018 11:00,14/04/2020 08:35,,385-392,,6,14,,,,,,,,,,,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NS9R2ZX5,conferencePaper,2009,"Singh, Ranjit; Singh, Ashok; Anumba, Chimay; Singh, Gurdev",WEB-BASED SYSTEMS APPROACH TO IMPROVEMENT OF PATIENT SAFETY,NASTEC 2009: 2ND INTERNATIONAL NORTH AMERICAN SIMULATION TECHNOLOGY CONFERENCE,978-90-77381-50-2,,,,"According to The World Health Organization patient safety is a Basic Human Right. It has, therefore, formed an Alliance for Patient Safety. The reason is that medical errors are a major cause of harm to patients. The authors support the assertion by the US Institute of Medicine that there can be no quality of care without patient safety. The unique nature of each healthcare setting means that `off-the-shelf' top-down solutions seldom work. The purpose of the work reported here therefore was to develop a bottom-up methodology in which staff is empowered through IT-assisted systems approach. This team-based approach is based upon an Error Reduction Intervention Cycle as follows: (i) an anonymous on-line survey in which all staff in a healthcare setting rate various errors according to their perceived frequency and severity; (ii) identification of priority areas based on hazard ratings derived from the survey results (supplemented by Delphi technique); (iii) development of solutions to the prioritized problems; (iv) implementation of the solutions, and tracking their effect/s, and (v) repetition of the survey for continuing safety-based quality improvement. The tool is highly adaptable for any health care setting. For the purposes of illustration the case of primary care settings, where the vast majority of any nation's healthcare takes place, is presented.",2009,21/11/2018 11:00,14/04/2020 08:35,,30-34,,,,,,,,,,,Univ St Anne; EUROSIS; Georgia Tech; Ghent Univ; Georgia Tech Global Learning Ctr,,,,,,,,,,"

2nd Int N American Simulation Technol Conference on Soft Computing, Simulation and Software Engineering, European Technol Inst, Atlanta, GA, AUG 26-28, 2009

",,,00; 110,,"Beldjehem, M",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LRZTGBZK,conferencePaper,2009,"Chunyan, Liu; Weiwei, Wang; Lanhai, Li",Outcomes and Challenges of Prevention and Control of Stroke - Applications of Systems Theory,"PROCEEDINGS OF 2009 CONFERENCE ON SYSTEMS SCIENCE, MANAGEMENT SCIENCE & SYSTEM DYNAMICS, VOL 4",978-7-121-09444-6,,,,"Stroke has a great impact on individual, family and society due to its high incidence, mortality, and residual disability of Survivors. It brings large challenges for national health system. There are ever-increasing budgets in the prevention and control of stroke, but outcomes are disappointing because the imbalance of the prevention and control. Effective methods are in need The complex causal chain of Stroke calls for the application of Systems Theory which is an effective method to solve complex problem. Stroke unit based on Systems Theory is brought and getting more and more attention. For a point view of Systems Theory, it is success in treating the stroke patient in hospital, but failure in reducing the expenditure because it did not take the primary prevention into account. This article attempts to apply Systems theory to explain the functionality of the stroke unit and expound the necessity to expand the present stroke-treatment-centered unit to a new style which takes prevention, treatment and post-treatment into considerations. The expanded Stroke Unit will help reducing stroke incidence and recurrence.",2009,21/11/2018 11:00,14/04/2020 08:34,,101-105,,,,,,,,,,,"Tongji Univ, Inst Dev Study; Syst Engn Soc China, Comm Syst Dynam; Syst Dynam Soc, China Chapter; Shanghai Inst Foreign Trade; Syst Dynam Soc, Chapters Asia Pacific Area",,,,,,,,,,"

Conference on Systems Science, Management Science and System Dynamics, Shanghai, PEOPLES R CHINA, MAY 29-31, 2009

",,,00; 110,,"Wang, Q and Zhang, XD and Xu, B and Wu, BC",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EGUMDHLQ,conferencePaper,2009,"Thomson, M. C.; Jeanne, I.; Djingarey, M.",Dust and epidemic meningitis in the Sahel: a public health and operational research perspective,WMO/GEO EXPERT MEETING ON AN INTERNATIONAL SAND AND DUST STORM WARNING SYSTEM,,,10.1088/1755-1307/7/1/012017,,"Now that the health communities attention is increasingly focused on climate-health interactions, it has become essential for health decision makers to better understand the role that climate plays in driving disease burdens and health outcomes (both now and in the future) and the opportunity for integrating climate knowledge and information into health decision-making processes to mitigate the negative and strengthen the positive of climate-health interactions. Here we explore the potential climatic indicators and the climate information needs of relevance to the meningitis prevention and control community engaged in the African `meningitis belt'.",2009,21/11/2018 11:00,14/04/2020 08:35,,,,,7,,,,IOP Conference Series-Earth and Environmental Science,,,,Barcelona Supercomp Ctr; World Meteorol Org; Grp Earth Observat; Agencia Estatal Meteorol; Consejo Super Invest Cientif,,,,,,,,,,"

WMO/GEO Expert Meeting on an International Sand and Dust Storm Warning System, Barcelona, SPAIN, NOV 07-09, 2007

",,,00; 100,,"Perez, JC and Baldasano, JM",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FYDBXW6E,journalArticle,2008,"Kaji, Amy H.; Bair, Aaron; Okuda, Yasuharu; Kobayashi, Leo; Khare, Rahul; Vozenilek, John","Defining Systems Expertise: Effective Simulation at the Organizational Level-Implications for Patient Safety, Disaster Surge Capacity, and Facilitating the Systems Interface",ACADEMIC EMERGENCY MEDICINE,,1069-6563,10.1111/j.1553-2712.2008.00209.x,,"The Institute of Medicine's report “To Err is Human” identified simulation as a means to enhance safety in the medical field, just as flight simulation is used to improve the aviation industry. Yet, while there is evidence that simulation may improve task performance, there is little evidence that simulation actually improves patient outcome. Similarly, simulation is currently used to model teamwork-communication skills for disaster management and critical events, but little research or evidence exists to show that simulation improves disaster response or facilitates intersystem or interagency communication. Simulation ranges from the use of standardized patient encounters to robot-mannequins to computerized virtual environments. As such, the field of simulation covers a broad range of interactions, from patient-physician encounters to that of the interfaces between larger systems and agencies. As part of the 2008 Academic Emergency Medicine Consensus Conference on the Science of Simulation, our group sought to identify key research questions that would inform our understanding of simulation's impact at the organizational level. We combined an online discussion group of emergency physicians, an extensive review of the literature, and a “public hearing” of the questions at the Consensus Conference to establish recommendations. The authors identified the following six research questions: 1) what objective methods and measures may be used to demonstrate that simulator training actually improves patient safety? 2) How can we effectively feedback information from error reporting systems into simulation training and thereby improve patient safety? 3) How can simulator training be used to identify disaster risk and improve disaster response? 4) How can simulation be used to assess and enhance hospital surge capacity? 5) What methods and outcome measures should be used to demonstrate that teamwork simulation training improves disaster response? and 6) How can the interface of systems be simulated? We believe that exploring these key research questions will improve our understanding of how simulation affects patient safety, disaster surge capacity, and intersystem and interagency communication.",2008-11,21/11/2018 11:00,14/04/2020 08:34,,1098-1103,,11,15,,,,,,,,,,,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, P9R28XAT,journalArticle,2008,"Cochran, J. K.; Roche, K.",A queuing-based decision support methodology to estimate hospital inpatient bed demand,JOURNAL OF THE OPERATIONAL RESEARCH SOCIETY,,0160-5682,10.1057/palgrave.jors.2602499,,"Hospital inpatient bed capacity might be better described as evolved than planned. At least two challenges lead to this behaviour: different views of patient demand implied by different data sets in a hospital and limited use of scientific methods for capacity estimation. In this paper, we statistically examine four distinct hospital inpatient data sets for internal consistency and potential usefulness for estimating true patient bed demand. We conclude that posterior financial data, billing data, rather than the census data commonly relied upon, yields true hospital bed demand. Subsequently, a capacity planning tool, based upon queuing theory and financial data only, is developed. The delivery mechanism is an Excel spreadsheet. One adjusts input parameters including patient volume and mix and instantaneously monitors the effect on bed needs across multiple levels of care. A case study from a major hospital in Phoenix, Arizona, USA is used throughout to demonstrate the methodologies.",2008-11,21/11/2018 11:00,14/04/2020 08:34,,1471-1482,,11,59,,,,,,,,,,,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ITH48F87,journalArticle,2008,"Cooper, K.; Davies, R.; Raftery, J.; Roderick, P.",Use of a coronary heart disease simulation model to evaluate the costs and effectiveness of drugs for the prevention of heart disease,JOURNAL OF THE OPERATIONAL RESEARCH SOCIETY,,0160-5682,10.1057/palgrave.jors.2602468,,"A discrete event simulation model of the patient pathways in the treatment of coronary heart disease (CHD) was used to quantify the health gains and costs associated with increasing secondary prevention drugs prescription for patients with CHD based on the level recommended in the National Service Framework for the UK. A Gompertz distribution was sampled for time to failure ( death or non-fatal heart attack). The time to failure was modified in relation to the reduced risk of failure for those on the relevant drugs. The results from the model were validated against national data. Increasing the levels of prescription of secondary prevention drugs to those patients with CHD might prevent 100 deaths per million population per year and cost an additional 4 pound million per million population per year. With cost per life year saved of 5520 pound, this appears good value for money compared with other health technologies.",2008-09,21/11/2018 11:00,14/04/2020 08:34,,1173-1181,,9,59,,,,,,,,,,,,,,,,,,,,,1; 410; discrete event simulation model,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, B7HLKLA9,journalArticle,2008,"Chi, Chih-Lin; Street, W. Nick; Ward, Marcia M.",Building a hospital referral expert system with a Prediction and Optimization-Based Decision Support System algorithm,JOURNAL OF BIOMEDICAL INFORMATICS,,1532-0464,10.1016/j.jbi.2007.10.002,,"This study presents a new method for constructing an expert system using a hospital referral problem as an example. Many factors, such as institutional characteristics, patient risks, traveling distance, and chances of survival and complications should be included in the hospital-selection decision. Ideally, each patient should be treated individually, with the decision process including not only their condition but also their beliefs about trade-offs among the desired hospital features. An expert system can help with this complex decision, especially when numerous factors are to be considered. We propose a new method, called the Prediction and Optimization-Based Decision Support System (PODSS) algorithm, which constructs an expert system without an explicit knowledge base. The algorithm obtains knowledge on its own by building machine learning classifiers from a collection of labeled cases. In response to a query, the algorithm gives a customized recommendation, using an optimization step to help the patient maximize the probability of achieving a desired outcome. In this case, the recommended hospital is the optimal solution that maximizes the probability of the desired outcome. With proper formulation, this expert system can combine multiple factors to give hospital-selection decision support at the individual level. (c) 2007 Elsevier Inc. All rights reserved.",2008-04,21/11/2018 11:00,14/04/2020 08:34,,371-386,,2,41,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, SN426NUQ,conferencePaper,2008,"Pylarinou, Charalambia; Koumanakos, Dimitrios; Hapsas, Antonios; Karacapilidis, Nikos; Adamides, Emmanuel",INTEGRATING SIMULATION INTO A WEB-BASED DECISION SUPPORT TOOL FOR THE COST EFFECTIVE PLANNING OF VESSEL DISMANTLING PROCESSES,"ICEIS 2008: PROCEEDINGS OF THE TENTH INTERNATIONAL CONFERENCE ON ENTERPRISE INFORMATION SYSTEMS, VOL AIDSS: ARTIFICIAL IN℡LIGENCE AND DECISION SUPPORT SYSTEMS",978-989-8111-37-1,,,,"Vessel dismantling is a complex process, which requires advanced planning subject to environmentally safe as well as cost and energy effective standards. Aiming to facilitate stakeholders involved in such activities and augment the quality of their related decision making, this paper presents an innovative decision support system that takes into account the diversity of the associated constraints (i.e. available resources, environmental issues, health and safety of the workforce, etc.). The proposed system aids stakeholders make decisions on qualitative issues such as the appropriateness of a disposal methodology or the level of the safety of the workforce in a specific dismantling yard. Being seamlessly integrated with a visual interactive simulation environment, the system facilitates the collaborative design and redesign of dismantling processes.",2008,21/11/2018 11:00,14/04/2020 08:35,,544-547,,,,,,,,,,,"Inst Syst & Technologies Informat, Control & Commun; Workflow Management Coalit; Assoc Adv Artificial Intelligence",,,,,,,,,,"

10th International Conference on Enterprise Information Systems, Barcelona, SPAIN, JUN 12-16, 2008

",,,00; 100,,"Cordeiro, J and Filipe, J",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HQVP3B6Q,conferencePaper,2008,"McClean, Sally; Millard, Peter; Garg, Lalit",Using Markov Models for Decision Support in Management of High Occupancy Hospital Care,IN℡LIGENT TECHNIQUES AND TOOLS FOR NOVEL SYSTEM ARCHITECTURES,978-3-540-77621-5,,,,"We have previously used Markov models to describe movements of patients between hospital states; these may be actual or virtual and described by a phase-type distribution. Here we extend this approach to a Markov reward model for a healthcare system with constant size. This corresponds to a situation where there is a waiting list of patients so that the total number of in-patients remains at a constant level and all admissions are from the waiting list. The distribution of costs is evaluated for any time and expressions derived for the mean cost. The approach is then illustrated by determining average cost at any time for a hospital system with two states: acute/rehabilitative and long-stay. In addition we develop a Markov model to determine patient numbers and costs at any time where, again, there is a waiting list, so admissions are taken from this list, but we now allow a fixed growth which declines to zero as time tends to infinity. As before, the length of stay is described by a phase-type distribution, thus enabling the representation of durations and costs in each phase within a Markov framework. As an illustration, the model is used to determine costs over time for a four phase model, previously fitted to data for geriatric patients. Such an approach can be used to determine the number of patients and costs in each phase of hospital care and a decision support system and intelligent patient management tool can be developed to help hospital staff, managers and policy makers, thus facilitating an intelligent and systematic approach to the planning of healthcare and optimal use of scarce resources.",2008,21/11/2018 11:00,14/04/2020 08:34,,187+,,,109,,,,Studies in Computational Intelligence,,,,IEEE,,,,,,,,,,"

3rd IEEE International Conference on Intelligent Systems, Univ Westminister, London, ENGLAND, SEP 04-06, 2006

",,,00; Review,,"Chountas, P and Petrounias, I and Kacprzyk, J",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TNBU6TIL,conferencePaper,2008,"Fumin, Zhuge; Gang, Zhou; Weimin, Cheng; Peng, Yang; Shengzhu, Zhang; Wen, Nie",Optimization Design of Dust Prevention Equipment by Water-Cloud System of Powered Roof Support in Fully Mechanized and Roof Caving Coal Face with Annual Yield of 6 Million Tons,"PROGRESS IN SAFETY SCIENCE AND TECHNOLOGY, VOL VII, PTS A AND B",978-7-03-022901-4,,,,"According to the actual situation of high quantity of productive dust of the 1303 face with annual yield of 6 million tons, the dust sources are analyzed. In order to reduce the dust concentration in this workface greatly, the methods, which are based on the 3D k-epsilon model of turbulent flow, such as volume-control method and CFD's SIMPLE (Semi-Implicit Method for Pressure-Linked Equations) method, are applied to do the ANSYS numerical simulation on the concentration and streamline of dust-flow field of the section. Then according to the performance test of nozzles for dust suppression of the powered support, the best type of nozzle, the water-supplying pressure of spraying and the nozzle's diameter are chosen. Finally the optimized design scheme of dust suppression device of the face 1303 is proposed. By the industrial test of the face 1303, the plan is proved to be scientific and rational which reduces the dust concentration of different procedures greatly. And the plan is also useful for the mines' safe production and workers' health.",2008,21/11/2018 11:00,14/04/2020 08:34,,1474-1478,,,7,,,,PROGRESS IN SAFETY SCIENCE AND TECHNOLOGY SERIES,,,,,,,,,,,,,,"

International Symposium on Safety Science and Technology, Beijing, PEOPLES R CHINA, SEP 24-27, 2008

",,,00; 100,,"Li, SC and Wang, YJ and An, Y and Sun, XY and Li, X",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BKZ7AYCX,journalArticle,2007,"Kranke, P.; Eberhart, L. H.; Gan, T. J.; Roewer, N.; Tramer, M. R.",Algorithms for the prevention of postoperative nausea and vomiting: an efficacy and efficiency simulation,EUROPEAN JOURNAL OF ANAESTHESIOLOGY,,0265-0215,10.1017/S0265021507000713,,"A number of algorithms for the prevention of postoperative nausea and vomiting have been proposed. Their efficacy and efficiency remains unclear. Methods: We assumed that four antiemetic interventions were similarly effective and achieved additive effects when combined. We applied published and hypothetical algorithms for the prevention of postoperative nausea and vomiting to patient populations with different baseline risks. As indicators of efficacy and efficiency we computed for each baseline risk and each algorithm the total number of patients receiving prophylaxis, the total number of administered interventions, the cumulative 24 h incidence of postoperative nausea and vomiting, and an Efficiency Index (i.e. the number of administered interventions divided by the achieved absolute risk reduction). This was done for cohorts of 100 patients. Results: Ten algorithms were tested in seven populations with different baseline risks. Algorithms were fixed (>= 1 intervention given to all patients, independent of baseline risk) or risk-adapted (>= 1 intervention administered depending on the presumed baseline risk). Risk-adapted algorithms were escalating (the greater the baseline risk, the more interventions are given) or dichotomous (a fixed number of interventions is given to high-risk patients only). With some algorithms, when applied to selected patient populations, the average postoperative nausea and vomiting incidence could be decreased below 15%; however, none produced consistent postoperative nausea and vomiting incidences below 20% across all populations. With all, the number of administered antiemetic interventions was the major factor for improved efficacy. Depending on the baseline risk, some algorithms offered potential towards improved efficiency. Conclusions: Despite improved knowledge on risk factors and antiemetic strategies, none of the tested algorithms completely prevents postoperative nausea and vomiting and none is universally applicable. Anesthesiologists should try to identify the most useful antiemetic strategy for a specific setting. That strategy may be prophylactic or therapeutic or a combination of both, and it should consider institutional policies and individual baseline risks.",2007-10,21/11/2018 11:00,14/04/2020 08:34,,856-867,,10,24,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XKBVIXGV,journalArticle,2007,"Merrill, Jacqueline; Bakken, Suzanne; Rockoff, Maxine; Gebble, Kristine; Carley, Kathleen M.",Description of a method to support public health information management: Organizational network analysis,JOURNAL OF BIOMEDICAL INFORMATICS,,1532-0464,10.1016/j.jbi.2006.09.004,,"In this case study, we describe a method that has potential to provide systematic support for public health information management. Public health agencies depend on specialized information that travels throughout an organization via communication networks among employees. Interactions that occur within these networks are poorly understood and are generally unmanaged. We applied organizational network analysis, a method for studying communication networks, to assess the method's utility to support decision making for public health managers, and to determine what links existed between information use and agency processes. Data on communication links among a health department's staff was obtained via survey with a 93% response rate, and analyzed using Organizational Risk Analyzer (ORA) software. The findings described the structure of information flow in the department's communication networks. The analysis succeeded in providing insights into organizational processes which informed public health managers' strategies to address problems and to take advantage of network strengths. (C) 2006 Elsevier Inc. All rights reserved.",2007-08,21/11/2018 11:00,14/04/2020 08:34,,422-428,,4,40,,,,,,,,,,,,,,,,,,,,,1; Network analysis; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WF7HBN4H,journalArticle,2007,"Frota Neto, J. Quariguasi; Angulo-Meza, L.",Alternative targets for data envelopment analysis through multi-objective linear programming: Rio de Janeiro Odontological Public Health System Case Study,JOURNAL OF THE OPERATIONAL RESEARCH SOCIETY,,0160-5682,10.1057/palgrave.jors.2602216,,"In the last 10 years much has been written about the drawbacks of radial projection. During this time, many authors proposed methods to explore, interactively or not, the efficient frontier via non-radial projections. This paper compares three families of data envelopment analysis (DEA) models: the traditional radial, the preference structure and the multi-objective models. We use the efficiency analysis of Rio de Janeiro Odontological Public Health System as a background for comparing the three methods through a real case with one integer and one exogenous variable. The objectives of the study case are ( i) to compare the applicability of the three approaches for efficiency analysis with exogenous and integer variables, (ii) to present the main advantages and drawbacks for each approach, (iii) to prove the impossibility to project in some regions and its implications, (iv) to present the approximate CPU time for the models, when this time is not negligible. We find that the multi-objective approach, although mathematically equivalent to its preference structure peer, allows projections that are not present in the latter. Furthermore, we find that, for our case study, the traditional radial projection model provides useless targets, as expected. Furthermore, for some parts of the frontier, none of the models provide suitable targets. Other interesting result is that the CPU-time for the multi-objective formulation, although its endogenous high complexity, is acceptable for DEA applications, due to its compact nature.",2007-07,21/11/2018 11:00,14/04/2020 08:34,,865-873,,7,58,,,,,,,,,,,,,,,,,,,,,100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 46MMJ26Z,journalArticle,2007,"Keating, Nancy L.; Ayanian, John Z.; Cleary, Paul D.; Marsden, Peter V.",Factors affecting influential discussions among physicians: A social network analysis of a primary care practice,JOURNAL OF GENERAL INTERNAL MEDICINE,,0884-8734,10.1007/s11606-007-0190-8,,"BACKGROUND: Physicians often rely on colleagues for new information and advice about the care of their patients. OBJECTIVE: Evaluate the network of influential discussions among primary care physicians in a hospital-based academic practice. DESIGN: Survey of physicians about influential discussions with their colleagues regarding women's health issues. We used social network analysis to describe the network of discussions and examined factors predictive of a physician's location in the network. SUBJECTS: All 38 primary care physicians in a hospital-based academic practice. MEASUREMENTS: Location of physician within the influential discussion network and relationship with other physicians in the network. RESULTS: Of 33 responding physicians (response rate= 87%), the 5 reporting expertise in women's health were more likely than others to be cited as sources of influential information (odds ratio [OR] 6.81, 95% Bayesian confidence interval [CI] 2.25-23.81). Physicians caring for more women were also more often cited (OR 1.03, 95% CI 1.01-1.05 for a 1 percentage-point increase in the proportion of women patients). Influential discussions were more frequent among physicians practicing in the same clinic within the practice than among those in different clinics (OR 5.03, 95% CI 3.10-8.33) and with physicians having more weekly clinical sessions (OR 1.33, 95% CI 1.15 to 1.54 for each additional session). CONCLUSIONS: In the primary care practice studied, physicians obtained information from colleagues with greater expertise and experience as well as colleagues who were accessible based on location and schedule. It may be possible to organize practices to promote more rapid dissemination of high-quality evidence-based medicine.",2007-06,21/11/2018 11:00,14/04/2020 08:34,,794-798,,6,22,,,,,,,,,,,,,,,,,,,,,1; network analysis; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EHEMPZSA,journalArticle,2007,"Brand, C.; Ibrahim, J.; Bain, C.; Jones, C.; King, B.",Engineering a safe landing: engaging medical practitioners in a systems approach to patient safety,INTERNAL MEDICINE JOURNAL,,1444-0903,10.1111/j.1445-5994.2007.01310.x,,"Background: Several event studies, including the Australian Safety and Quality in Healthcare Study, emphasize gaps in safety for hospitalized patients. It is now recognized that system-based factors contribute significantly to risk of adverse events and this has led to a shift in focus of patient safety from the autonomous responsibility of medical clinicians to a systems-based approach. The aim of this study was to determine medical practitioner awareness of, level of engagement in and barriers to engagement in a systems approach to patient safety and quality. Results: Information from acute and subacute care medical practitioners at a metropolitan public hospital was collected within an anonymous structured electronic survey, a discussion group and key informant interviews. Methods: There were 73 survey respondents (response rate 7.6%). Fifty-one (69.9%) were unaware of the Institute of Medicine report `To Err is human'. Thirty-six (49.3%) were unaware of the Australian Quality in Healthcare Study and 12 (16.4%) had read the article. There was a positive relation identified between awareness and seniority. There was a low level of participation in systems-focused quality and safety activities and limited understanding of the role of systems in medical error causation. There was uncertainty about the changing role of medical practitioners in patient safety and perceived lack of skills to effectively engage with hospital management about safety and quality issues. Conclusion: Several factors are limiting engagement of medical practitioners in a systems approach to patient safety. Increased educational support is needed and may be best focused within clinical effectiveness activities pertinent to practitioner interest and expertise.",2007-05,21/11/2018 11:00,14/04/2020 08:34,,295-302,,5,37,,,,,,,,,,,,,,,,,,,,,Humans; *Quality of Health Care; Female; Male; *Safety; Safety Management/*organization & administration; Attitude of Health Personnel; Health Personnel; 1; Patient Care Management/*organization & administration; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TCFS8TC8,journalArticle,2007,"Solberg, Leif I.; Klevan, David H.; Asche, Stephen E.","Crossing the quality chasm for diabetes care: The power of one physician, his team, and systems thinking",JOURNAL OF THE AMERICAN BOARD OF FAMILY MEDICINE,,1557-2625,10.3122/jabfm.2007.03.060132,,"Objective: To demonstrate that one physician can dramatically improve care of diabetes patients by taking a systems approach and getting support from leaders and other team members Material and Methods: Pre-/postcomparison of quality measures for the diabetes patients of one primary care physician, compared with those of his entire large multi-specialty medical group. Working with a mentor and with clinic and medical group leaders, he established a clear goal, focused on a repeatable and important performance measure, and used repeated rapid cycle trials to make systems changes in care, with extensive task delegation to team members and emphasis on repeated testing and treatment intensification. The composite outcome measure requires that each diabetes patient meet all 5 of the following: LDL < 100, HbA(1c) < 7, systolic blood pressure < 130, regular aspirin use, and tobacco-free status. Results: Over a 24-month period, quarterly measures for this physician's patients rose from 5.7% to 42.9%, while the 7000 diabetes patients of the entire medical group only increased from 4.2% to 12.1%. The change for those patients who stayed under his care for the entire period was even more dramatic - from 2.3% to 46.5% ( P = <. 0001). The largest improvements were for smoking documentation, aspirin use, and LDL control, with little change in HbA(1c) levels. Conclusion: One physician can accomplish a lot, if improvement is approached both systematically and persistently and if the work is coordinated with and supported by practice leaders.",2007-06,21/11/2018 11:00,14/04/2020 08:35,,299-306,,3,20,,,,,,,,,,,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CYJTE56V,journalArticle,2007,"Thunhurst, C.",Refocusing upstream: Operational research for population health,JOURNAL OF THE OPERATIONAL RESEARCH SOCIETY,,0160-5682,10.1057/palgrave.jors.2602241,,"This paper examines the potential for the application of OR methods to `upstream' problems in health sector planning. These address the underlying causes of ill health, and stand in contrast to `downstream' health service planning which addresses the consequences of ill health. The paper reviews the emergence, globally and locally, of recognition of the importance of upstream planning and policy formation for the health sectors of both developed and developing countries. It presents examples of the use of OR techniques in upstream health planning, with particular illustrations taken from the area of health impact assessment. It argues for a fuller appreciation of the potential contribution of OR in this and in other areas of upstream health sector planning.",2007-02,21/11/2018 11:00,14/04/2020 08:35,,186-194,,2,58,,,,,,,,,,,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QSPBCKGW,conferencePaper,2007,"Cervantes, Louie; Lee, Yong-Seok; Yang, Hyunho; Ko, Sung-Hyun; Lee, Jaewan",Agent-based intelligent decision support for the home healthcare environment,ADVANCES IN HYBRID INFORMATION TECHNOLOGY,978-3-540-77367-2,,,,This paper brings together the multi-agent platform and artificial neural network to create an intelligent decision support system for a group of medical specialists collaborating in the pervasive management of healthcare for chronic patients. Artificial intelligence is employed to support the management of chronic illness through the early identification of adverse trends in the patient's physiological data. A framework based on software agents that proxy for participants in a home healthcare environment is presented. The proposed approach enables the agent-based home healthcare system to identify the emergent chronic conditions from the patterns of symptoms and allows the appropriate remediation to be initiated and managed transparently.,2007,21/11/2018 11:00,14/04/2020 08:34,,414-424,,,4413,,,,Lecture Notes in Computer Science,,,,SERC; SERSC,,,,,,,,,,"

1st International Conference on Hybrid Information Technology, Cheju Isl, SOUTH KOREA, NOV 09-11, 2006

",,,00; 100,,"Szczuka, MS and Howard, D and Slezak, D and Kim, HK and Kim, TH and Ko, IS",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IKNV3D5N,journalArticle,2007,"Liem, Su-San; van der Hoeven, Barend L.; Oemrawsingh, Pranobe V.; Bax, Jeroen J.; van der Bom, Johanna G.; Bosch, Jan; Viergever, Eric P.; van Rees, Cees; Padmos, Iman; Sedney, Meredith I.; van Exel, Henk J.; Verwey, Harriette F.; Atsma, Douwe E.; van der Velde, Enno T.; Jukema, J. Wouter; van der Wall, Ernst E.; Schalij, Martin J.",MISSION! Optimization of acute and chronic care for patients with acute myocardial infarction,AMERICAN HEART JOURNAL,,0002-8703,10.1016/j.ahj.2006.10.002,,"Background Guideline implementation programs for patients with acute myocardial infarction (AMI) enhance adherence to evidence-based medicine (EBM) and improve clinical outcome. Although undertreatment of patients with AMI is well recognized in both acute and chronic phases of care, most implementation programs focus on acute and secondary prevention strategies during the index hospitalization phase only. Hypothesis Implementation of an all-phase integrated AMI care program maximizes EBM in daily practice and improves the care for patients with AMI. Aim The objective of this study is to assess the effects of the MISSION! program on adherence to EBM for patients with AMI by the use of performance indicators. Design The MISSION! protocol is based on the most recent American College of Cardiology/American Heart Association and European Society of Cardiology guidelines for patients with AMI. It contains a prehospital, inhospital, and outpatient clinical framework for decision making and treatment, up to 1 year after the index event. MISSION! concentrates on rapid AMI diagnosis and early reperfusion, followed by active lifestyle improvement and structured medical therapy. Because MISSIONI covers both acute and chronic AMI phase, this design implies an intensive multidisciplinary collaboration among all regional health care providers. Conclusion Continuum of care for patients with AMI is warranted to take full advantage of EBM in day-to-day practice. This manuscript describes the rationale, design, and preliminary results of MISSIONI, an all-phase integrated AMI care program.",2007-01,21/11/2018 11:00,14/04/2020 08:34,,,,1,153,,,,,,,,,,,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2UI66XUV,journalArticle,2007,"Luke, Douglas A.; Harris, Jenine K.","Network analysis in public health: History, methods, and applications",ANNUAL REVIEW OF PUBLIC HEALTH,,0163-7525,10.1146/annurev.publhealth.28.021406.144132,,"Network analysis is an approach to research that is uniquely suited to describing, exploring, and understanding structural and relational aspects of health. It is both a methodological tool and a theoretical paradigm that allows us to pose and answer important ecological questions in public health. In this review we trace the history of network analysis, provide a methodological overview of network techniques, and discuss where and how network analysis has been used in public health. We show how network analysis has its roots in mathematics, statistics, sociology, anthropology, psychology, biology, physics, and computer science. In public health, network analysis has been used to study primarily disease transmission, especially for HIV/AIDS and other sexually transmitted diseases; information transmission, particularly for diffusion of innovations; the role of social support and social capital; the influence of personal and social networks on health behavior; and the interorganizational structure of health systems. We conclude with future directions for network analysis in public health.",2007,21/11/2018 11:00,14/04/2020 08:34,,69-93,,,28,,,,Annual Review of Public Health,,,,,,,,,,,,,,,,,"Humans; *Public Health Practice; *Social Support; Information Dissemination; Health Behavior; Diffusion of Innovation; 00; Behavioral Research/*methods; *Disease Transmission, Infectious; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RVIUIK2X,conferencePaper,2007,"Yu, Lei; Xue, Huifeng",Crisis management simulation of public health accident based on evolutionary game theory,"DCABES 2007 Proceedings, Vols I and II",978-7-5352-3854-2,,,,"Based on the theory of Complexity Adaptive System, we attempt to study the crisis management system of public health accident through evolutionary game theory and simulate the evolutionary game through SWARM tool. Evolutionary game theory is based on bounded rationality, takes the community as the research object, and it provides the decision-making basis to the crisis management system of public health accident.",2007,21/11/2018 11:00,14/04/2020 08:35,,146-148,,,,,,,,,,,Wuhan Univ Technol; Comp Acad Assoc; Minist Educ; Natl Nat Sci Fdn China,,,,,,,,,,"

International Symposium on Distributed Computing and Applications to Business, Engineering and Science, Yichang, PEOPLES R CHINA, AUG 14-17, 2007

",,,00; 100,,"Guo, QP",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8HYKWLT2,conferencePaper,2007,"McGowan, Julie J.; Richwine, Margaret W.; Overhage, J. Marc","A Sustainable, Multi-Organizational Model for Decision Support During Public Health Emergencies","MEDINFO 2007: PROCEEDINGS OF THE 12TH WORLD CONGRESS ON HEALTH (MEDICAL) INFORMATICS, PTS 1 AND 2: BUILDING SUSTAINABLE HEALTH SYSTEMS",978-1-58603-774-1,,,,"In an effort to provide decision support during times of public health emergencies, Regenstrief Institute, Inc. and the Indiana University School of Medicine, in partnership with the county and state health departments, created a sustainable model to deliver information to health care providers and public health workers. The model leverages extant systems and processes, including active surveillance through electronic laboratory reporting, delivery of health information as part of the Indiana Health Information Exchange, and evidence based utilities and Blog technology to create a public health utility with disease specific information and epidemiologic reporting requirements.",2007,21/11/2018 11:00,14/04/2020 08:34,,1465+,,,129,,,,Studies in Health Technology and Informatics,,,,Hlth Informat Soc Australia,,,,,,,,,,"

12th World Congress on Health (Medical) Informatics, Brisbane, AUSTRALIA, AUG 20-24, 2007

",,,00; 100,,"Kuhn, KA and Warren, JR and Leong, TY",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ECQ2AXS7,conferencePaper,2007,"Sokolova, Marina V.; Fernandez-Caballero, Antonio",An agent-based decision support system for ecological-medical situation analysis,"NATURE INSPIRED PROBLEM-SOLVING METHODS IN KNOWLEDGE ENGINEERING, PT 2, PROCEEDINGS",978-3-540-73054-5,,,,"This paper presents an architecture of an agent-based decision support system (ADSS) for ecological-medical situation assessment. The system receives statistical information in form of direct and indirect pollution indicator values. The ultimate goal of the modeled multi-agent system (MAS) is to evaluate the impact of the exposure to pollutants in population health. The proposed ADSS interacts with humans in real-time “what-if” scenarios, providing the user with evidence for optimal decision making. A detailed description of all the agents and their BDI (beliefs, desires, intentions) cards is presented.",2007,21/11/2018 11:00,14/04/2020 08:35,,511+,,,4528,,,,Lecture Notes in Computer Science,,,,,,,,,,,,,,"

2nd International Work-Conference on the Interplay Between Natural and Artificial Computation, La Manga del Mar Menor, SPAIN, JUN 18-21, 2007

",,,00; 100,,"Mira, J and Alvarez, JR",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VIE3RRIA,conferencePaper,2007,"Balasubramanian, Hari; Banerjee, Ritesh; Gregg, Melissa; Denton, Brian T.",Improving primary care access using simulation optimization,"PROCEEDINGS OF THE 2007 WINTER SIMULATION CONFERENCE, VOLS 1-5",978-1-4244-1305-8,,,,"Primary care providers (PCPs) provide the majority of care patients receive during their lifetime. We consider the problem of determining the size and composition of physician panels in primary care. A physician's panel consists of a set of patients and each patient belongs to one of many different health-related categories. Using real data collected at the Mayo Clinic at Rochester, we propose a multi-period metaheuristic simulation optimization model for determining the panel design of a set of physicians working in a primary care environment. The model seeks to maximize patient visits to their own providers, reduce waiting times, and minimize overage.",2007,21/11/2018 11:00,14/04/2020 08:34,,1473-1479,,,,,,,,,,,,,,,,,,,,,"

2007 Winter Simulation Conference, Washington, DC, DEC 09-12, 2007

",,,1; 110; Metaheuristic simulation optimization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Q5W6CNFJ,journalArticle,2006,"Aaby, Kay; Herrmann, Jeffrey W.; Jordan, Carol S.; Treadwell, Mark; Wood, Kathy",Montgomery Countys Public Health Service uses operations research to plan emergency mass dispensing and vaccination clinics,INTERFACES,,0092-2102,10.1287/inte.1060.0229,,"To curb outbreaks of contagious diseases, county health departments must set up and operate clinics to dispense medications and vaccines. Carefully planning these clinics in advance of such an event is difficult and important. We developed and implemented operations research models to improve clinic planning for the Montgomery County (Maryland) Public Health Services. They include discrete-event simulation models and capacity-planning and queueing-system models. We validated these models using data that we collected during full-scale simulations of disease outbreaks. We also developed guidelines for the physical design of clinics based on general queueing principles and our own experiences.",2006-12,21/11/2018 11:00,14/04/2020 08:34,,569-579,,6,36,,,,,,,,,,,,,,,,,,,,,00; ******To read; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WQRCLQAR,journalArticle,2006,"Hsieh, Ji-Lung; Sun, Chuen-Tsai; Kao, Gloria Yi-Ming; Huang, Chung-Yuan",Teaching through simulation: Epidemic dynamics and public health policies,SIMULATION-TRANSACTIONS OF THE SOCIETY FOR MODELING AND SIMULATION INTERNATIONAL,,0037-5497,10.1177/0037549706074487,,"A growing number of epidemiologists are now working to refine computer simulation methods for diseases as a strategy for helping public policy decision-makers assess the potential efficacies of tactics in response to newly emerging epidemics. These efforts spiked after the SARS outbreak of 2002-2003. Here we describe our attempt to help novice researchers understand epidemic dynamics with the help of the cellular automata with social mirror identity model (CASMIM), a small-world epidemiological simulation system created by Huang et al. in 2004. Using the SARS scenario as a teaching example, we designed three sets of instructional experiments to test our assumptions regarding (i) simulating epidemic transmission dynamics and associated public health policies, (ii) assisting with understanding the properties and efficacies of various public health policies, (iii) constructing an effective, low-cost (in social and financial terms) and executable suite of epidemic prevention strategies, and (iv) reducing the difficulties and costs associated with learning epidemiological concepts. With the aid of the proposed simulation tool, novice researchers can create various scenarios for discovering epidemic dynamics and for exploring applicable combinations of prevention or suppression strategies. Results from an evaluative test indicate a significant improvement in the ability of a group of college students with little experience in epidemiology to understand epidemiological concepts.",2006-11,21/11/2018 11:00,14/04/2020 08:34,,731-759,,11,82,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KWP2VS3S,journalArticle,2006,"de Anda, D",Baby think it over: Evaluation of an infant simulation intervention for adolescent pregnancy prevention,HEALTH & SOCIAL WORK,,0360-7283,10.1093/hsw/31.1.26,,"In an intervention aimed at showing students the amount of responsibility involved in caring for an infant, 353 predominantly ninth-grade and Latino students carried the Baby Think It Over simulation doll in an intervention and completed matched pre- and posttest measures. Statistically significant gains were found on the total score and the impact of having a baby on academics, social life, and other family members; emotional risks; understanding and handling an infant's crying; and apprehension of the amount of responsibility involved in infant care. On a posttest-only measure, 108 participants reported statistically significant differences before and after carrying the doll with regard to the age at which they wished to have a child, their career and education plans, and the perceived interference of an infant with those education and career plans and their social life.",2006-02,21/11/2018 11:00,14/04/2020 08:34,,26-35,,1,31,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, R9EY3M8M,conferencePaper,2006,"Hu, Haitang; Bao, Shuming; Xu, Bing; Liang, Song","An integrated environment for spatio-temporal analysis, simulation and representation for public health research",GEOINFORMATICS 2006: GNSS AND INTEGRATED GEOSPATIAL APPLICATIONS,978-0-8194-6527-6,,10.1117/12.712273,,"Geographic space, as the arena within which all of the natural and social processes occur, and time, have become key research components of social science for the past two decades. However, most GIS software packages lack the predictive and analytic capabilities for complex problems, such as spatial statistical methods and spatial modeling. Meanwhile, the spatio-temporally explicit representation of complex, heterogeneous and dynamic geographic data sets is a particularly challenging issue. Many efforts have been made in developing tools for effective representation of health data, spatio-temporal analysis of the data, and the dynamic process simulation of disease transmission. To meet this demand, we attempted to develop a tool for integrating spatio-temporal analysis, simulation and representation of health data and processes. In this paper, we will introduce some methods for spatial temporal data analysis and their applications in public health. We'll describe the conceptual model of spatial temporal process simulation and the process-oriented spatio-temporal data model adopted in the tool we developed. After that, we'll present the framework of our integrated research toolkit, and demonstrate how to conduct analysis, modeling, and simulation with this software. Finally, we will discuss some issues for future studies.",2006,21/11/2018 11:00,14/04/2020 08:34,,,,,6418,,,,Proceedings of SPIE,,,,"Wuhan Univ; State Key Lab Informat Engn Surveying, Mapping & Remote Sensing; Int Assoc Chinese Professionals Geograph Informat Sci; Nat Sci Fdn China; Chinese Acad Surveying & Mapping; Heilongjiang Bureau Surveying & Mapping; Int Assoc Chinese Professionals Global Posit Syst; IEEE GRSS; ISPRS",,,,,,,,,,"

14th International Conference on Geoinformatics, Wuhan, PEOPLES R CHINA, OCT 28-29, 2006

",,,1; 100,,"Li, D and Xia, LY",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VAUSYVS4,journalArticle,2005,"Scott, J; Tallia, A; Crosson, JC; Orzano, AJ; Stroebel, C; DiCicco-Bloom, B; O'Malley, D; Shaw, E; Crabtree, B",Social network analysis as an analytic tool for interaction patterns in primary care practices,ANNALS OF FAMILY MEDICINE,,1544-1709,10.1370/afm.344,,"PURPOSE Social network analysis (SNA) provides a way of quantitatively analyzing relationships among people or other information-processing agents. Using 2 practices as illustrations, we describe how SNA can be used to characterize and compare communication patterns in primary care practices. METHODS Based on data from ethnographic field notes, we constructed matrices identifying how practice members interact when practice-level decisions are made. SNA software (UClNet and KrackPlot) calculates quantitative measures of network structure including density, centralization, hierarchy and clustering coefficient. The software also generates a visual representation of networks through network diagrams. RESULTS The 2 examples show clear distinctions between practices for all the SNA measures. Potential uses of these measures for analysis of primary care practices are described. CONCLUSIONS SNA can be useful for quantitative analysis of interaction patterns that can distinguish differences among primary care practices.",2005-10,21/11/2018 11:00,14/04/2020 08:35,,443-448,,5,3,,,,,,,,,,,,,,,,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2G4HIBLF,journalArticle,2005,"Cook, R; Rasmussen, J",“Going solid”: a model of system dynamics and consequences for patient safety,QUALITY & SAFETY IN HEALTH CARE,,1475-3898,10.1136/qshc.2003.009530,,"Rather than being a static property of hospitals and other healthcare facilities, safety is dynamic and often on short time scales. In the past most healthcare delivery systems were loosely coupled - that is, activities and conditions in one part of the system had only limited effect on those elsewhere. Loose coupling allowed the system to buffer many conditions such as short term surges in demand. Modern management techniques and information systems have allowed facilities to reduce inefficiencies in operation. One side effect is the loss of buffers that previously accommodated demand surges. As a result, situations occur in which activities in one area of the hospital become critically dependent on seemingly insignificant events in seemingly distant areas. This tight coupling condition is called “going solid”. Rasmussen's dynamic model of risk and safety can be used to formulate a model of patient safety dynamics that includes “going solid” and its consequences. Because the model addresses the dynamic aspects of safety, it is particularly suited to understanding current conditions in modern healthcare delivery and the way these conditions may lead to accidents.",2005-04,21/11/2018 11:00,14/04/2020 08:34,,130-134,,2,14,,,,,,,,,,,,,,,,,,,,,"Humans; Systems Analysis; *Models, Organizational; Organizational Case Studies; System dynamics; Efficiency, Organizational; *Safety Management; Medical Errors/*prevention & control; Organizational Innovation; *Hospital Administration; Risk Management; 1; *Organizational Culture; Workload; 220",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CVZDQINM,journalArticle,2005,"Rauner, MS; Brailsford, SC; Flessa, S",Use of discrete-event simulation to evaluate strategies for the prevention of mother-to-child transmission of HIV in developing countries,JOURNAL OF THE OPERATIONAL RESEARCH SOCIETY,,0160-5682,10.1057/palgrave.jors.2601884,,"HIV/AIDS affects over 40 million people worldwide, and more than 70% of these people live in Africa. Mother-to-child transmission of HIV accounts for over 90% of all HIV infections in children under the age of 15 years. However, implementing HIV prevention policies in Africa is extremely difficult because of the poor medical and socio-economic infrastructure. In this paper, we present a discrete-event simulation model that evaluates the relative benefits of two potentially affordable interventions aimed at preventing mother-to-child transmission of HIV, namely anti-retroviral treatment at childbirth and/or bottlefeeding strategies. The model uses rural Tanzanian data and compares different treatment policies. Our results demonstrate that strategic guidelines about breastfeeding are highly dependent on the assumed increase in infant mortality due to bottlefeeding, the efficacy of anti-retroviral treatment at childbirth, and the maternal health stage. The cost of averted infections, though low by Western standards, may represent significant obstacles to policy implementation in developing countries.",2005-02,21/11/2018 11:00,14/04/2020 08:35,,222-233,,2,56,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, R2TI6G7B,conferencePaper,2005,"Kadirkamanathan, V",Intelligent decision support systems on the grid for the health monitoring of complex systems,2005 IEEE International Workshop on Intelligent Signal Processing (WISP),0-7803-9030-X,,,,,2005,21/11/2018 11:00,14/04/2020 08:34,,3,,,,,,,,,,,IEEE Instrumentat & Measurement Soc,,,,,,,,,,"

IEEE International Workshop on Intelligent Signal Processing (WISP), Faro, PORTUGAL, SEP 01-03, 2005

",,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3FSXLJ2Y,conferencePaper,2005,"Thapa, D; Jung, IS; Wang, GN",Agent based decision support system using reinforcement learning under emergency circumstances,"ADVANCES IN NATURAL COMPUTATION, PT 1, PROCEEDINGS",3-540-28323-4,,,,"This paper deals with agent based decision support system for patient's right diagnosis and treatment under emergency circumstance. The well known reinforcement learning is utilized for modeling emergency healthcare system, Also designed is a novel interpretation of Markov decision process providing clear mathematical formulation to connect reinforcement learning as well as to express integrated agent system. Computational issues are also discussed with the corresponding solution procedure.",2005,21/11/2018 11:00,14/04/2020 08:35,,888-892,,,3610,,,,LECTURE NOTES IN COMPUTER SCIENCE,,,,Xiangtang Univ; IEEE Circuits & Syst Soc; IEEE Computat Intelligence Soc; IEEE Control Syst Soc; Int Neural Network Soc; European Neural Network Soc; Chinese Assoc Artificial Intelligence; Japanese Neural Network Soc; Int Fuzzy Syst Assoc; Asia Pacific Neural Network Assembly; Fuzzy Math & Syst Assoc China; Hunan Comp Federat,,,,,,,,,,"

1st International Conference on Natural Computation (ICNC 2005), Changsha, PEOPLES R CHINA, AUG 27-29, 2005

",,,00; 110,,"Wang, L and Chen, K and Ong, YS",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3DR265ZK,conferencePaper,2005,"Pour, G; Mishra, A; Mishra, L",A mobile agent-based approach to building mobile systems for health care management,"EEE `05: Proceedings of the 2005 International Conference on E-Business, Enterprise Information Systems, E-Government, and Outsourcing",,,,,"Mobile health care management systems are in its infancy. Research is underway to develop systems that will provide authorized users (e.g. doctors, patients, and pharmacists) with convenient, fast and reliable access to health care management using wireless mobile devices. The main research objective is to address the data communications issues in wireless mobile computing environments. In this applied research, co-sponsored by IBM and Hewlett-Packard, we have studied the issues, and explored mobile agent-based approach to address those issues. We have developed a new mobile agent-based architecture for mobile health care management systems, and built a prototype of the new system. This paper provides the latest results of this applied research. It also presents our new mobile agent-based architecture and the demonstration prototype of the new system using this architecture.",2005,21/11/2018 11:00,14/04/2020 08:34,,111-119,,,,,,,,,,,CSREA; Int Technol Inst; World Acad Sci Informat Technol,,,,,,,,,,"

International Conference on E-Business, Enterprise Information Systems, E-Government and Outsourcing, Las Vegas, NV, JUN 20-23, 2005

",,,1; agent based; 420,,"Arabnia, HR",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 36IGRECF,journalArticle,2004,"Tengs, TO; Ahmad, S; Moore, R; Gage, E",Federal policy mandating safer cigarettes: A hypothetical simulation of the anticipated population health gains or losses,JOURNAL OF POLICY ANALYSIS AND MANAGEMENT,,0276-8739,10.1002/pam.20051,,"If manufacturing a safer cigarette is technically possible-an open question-then mandating that tobacco manufacturers improve the safety of cigarettes would likely have both positive and negative implications for the nation health. On the one hand, removing toxins may reduce the incidence of smoking-related diseases and premature mortality in smokers. On the other hand, smokers might be less inclined to quit, those who have quit might resume the habit, and youth who have never smoked will have one less reason to avoid tobacco use. To assess the expected population health impacts of a legislative or regulatory mandate, we created the Tobacco Policy Model, a system dynamics computer simulation model. The model relies on secondary data and simulates the U.S. population over time spans as long as 50 years. Our simulation results reveal that even if requiring cigarettes to be safer makes smoking more attractive and increases tobacco use, a net gain in population health is still possible. (C) 2004 by the Association for Public Policy Analysis and Management.",2004,21/11/2018 11:00,14/04/2020 08:35,,857-872,,4,23,,,,,,,,,,,,,,,,,,,,,"Humans; Health Policy; United States; Forecasting; *Quality-Adjusted Life Years; *Health Status; *Models, Theoretical; Smoking Cessation; *Health Behavior; Recurrence; 00; *Consumer Product Safety; Federal Government; Smoking/*mortality/trends; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, X8QYSBCX,journalArticle,2004,"Ortegon, MM; Redekop, WK; Niessen, LW",Cost-effectiveness of prevention and treatment of the diabetic foot - A Markov analysis,DIABETES CARE,,0149-5992,10.2337/diacare.27.4.901,,"OBJECTIVE - To estimate the lifetime health and economic effects of optimal prevention and treatment of the diabetic foot according to international Standards and to determine the cost-effectiveness of these interventions in the Netherlands. RESEARCH DESIGN AND METHODS - A risk-based Markov model was developed to simulate the onset and progression of diabetic foot disease in patients with newly diagnosed type 2 diabetes managed with care according to guidelines for their lifetime. Mean survival time, quality of life, foot complications, and costs were the outcome measures assessed. Current care was the reference comparison. Data from Dutch studies on the epidemiology of diabetic foot disease, health care use, and costs, complemented with information from international studies, were used to feed the model. RESULTS - Compared with current care, guideline-based care resulted in improved life expectancy, gain of quality-adjusted life-years (QALYs), and reduced incidence of foot complications. The lifetime Costs of management of the diabetic foot following guideline-based care resulted in a cost per QALY gained of <$25,000, even for levels of preventive foot care as low as 10%. The cost-effectiveness varied sharply, depending on the level of foot ulcer reduction attained. CONCLUSIONS - Management of the diabetic foot according to guideline-based care improves survival, reduces diabetic foot complications, and is cost-effective and even cost saving compared with standard care.",2004-04,21/11/2018 11:00,14/04/2020 08:35,,901-907,,4,27,,,,,,,,,,,,,,,,,,,,,"Humans; Netherlands; Cost-Benefit Analysis; Quality-Adjusted Life Years; Treatment Outcome; Aged; Cohort Studies; Markov Chains; Quality of Life; Practice Guidelines as Topic; *Health Care Costs; Models, Economic; Life Expectancy; Preventive Medicine/*economics; 1; Descriptive Statistics; Human; Data Analysis Software; Middle Age; Cost Benefit Analysis; Statistical; Data Analysis; Diabetes Mellitus – Mortality; Amputation – Economics; Diabetic Foot – Economics; Diabetic Foot – Prevention and Control; Diabetic Foot – Therapy; Diabetic Foot/*prevention & control/*therapy; Markov; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GVKV8JF3,journalArticle,2003,"Davies, R; Roderick, P; Raftery, J",The evaluation of disease prevention and treatment using simulation models,EUROPEAN JOURNAL OF OPERATIONAL RESEARCH,,0377-2217,10.1016/S0377-2217(02)00783-X,,"Health policy models provide measures of the effectiveness and costs of complex health care interventions making it possible to compare different policies. We look at the validity of models of screening, prevention and treatment, focusing on two simulation studies. In designing models, account must be taken of disease trends and changing treatment patterns. The choice of modelling technique and of system boundaries are shown to have an impact on results. Decisions have to be made about data which may be scarce or inappropriate for modelling purposes. Cost-effectiveness measures are based on the ratio of costs to benefits, such as life years saved or quality adjusted life years. These are sensitive to the time period and the discount rates chosen. Policy makers should be aware of these different sources of variability or error. For decision making purposes, the calculation of output measures must be based on the same assumptions. (C) 2002 Elsevier Science B.V. All rights reserved.",01/10/2003,21/11/2018 11:00,14/04/2020 08:34,,53-66,,1,150,,,,,,,,,,,,,,,,,,"

27th Meeting of the EURO-Working-Group-on-Operational-Research-Applied-to-Health-Services (ORAHS), VIENNA, AUSTRIA, JUL 30-AUG 03, 2001

",,,1; ******To read; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Q9ZLHBTR,journalArticle,2003,"Zeghnoun, A; Czernichow, P; Declercq, C",Assessment of short-term association between health outcomes and ozone concentrations using a Markov regression model,ENVIRONMETRICS,,1180-4009,10.1002/env.585,,"Longitudinal binary data are often used in panel studies where short-term associations between air pollutants and respiratory health outcomes are investigated. A Markov regression model in which the transition probabilities depend on the covariates, as well as the past responses, was used to study the short-term association between daily ozone (O-3) concentrations and respiratory health outcomes in a panel of schoolchildren in Armentieres, Northern France. The results suggest that there was a small but statistically significant association between O-3 and children's cough episodes. A 10 mug/m(3) increase in O-3 concentrations was associated with a 13.9% increase in cough symptoms (CI 95% = 1.2-28.1%). The use of a Markov regression model can be useful as it permits one to address easily both the regression objective and the stochastic dependence between successive observations. However, it is important to verify the sensitivity of the Markov regression parameters to the time-dependence structure. In this study, it was found that, although what happened on the previous day was a strong predictor of what happened on the current day, this did not contradict the O-3-respiratory symptom associations. Compared to the Markov regression model, the signs of the parameter estimates of marginal and random-intercept models remain the same. The magnitudes of the O-3 effects were also essentially the same in the three models, whose confidence intervals overlapped. Copyright (C) 2003 John Wiley Sons, Ltd.",2003-05,21/11/2018 11:00,14/04/2020 08:35,,271-282,,3,14,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6H32SVSI,journalArticle,2003,"Lindgren, P; Fahlstadius, P; Hellenius, ML; Jonsson, B; de Faire, U",Cost-effectiveness of primary prevention of coronary heart disease through risk factor intervention in 60-year-old men from the county of Stockholm - a stochastic model of exercise and dietary advice,PREVENTIVE MEDICINE,,0091-7435,10.1016/S0091-7435(02)00060-9,,"Background. Recent screenings show a high prevalence of cardiovascular risk factors in the county of Stockholm. Primary prevention may be a way to lower the risk burden of coronary heart disease, but we must establish that preventive programs are cost-effective. Methods. Through the use of a stochastic Markov model, which predicts reduction in coronary heart disease events based on risk factor reductions, this study evaluates the results of a previous controlled trial in middle-aged men comparing dietary advice, exercise, and the combination of both applied to an observed cohort of 60-year-old men in the county of Stockholm. Results. The model predicts lower costs and higher effectiveness for dietary advice compared to the alternatives. Assuming a declining effect of the intervention, dietary advice saves 0.0228 life-years compared to no intervention. If no decline is assumed, the corresponding figure is 0.0997 life-years. From the societal perspective, the added costs are 2,892 Swedish Kronor (SEK) and 14,106 SEK for the two modeling assumptions, resulting in a cost-effectiveness of 127,065 SEK per life-year gained (LYG) and 141,555 SEK/LYG. These figures are below what is generally thought of as cost-effective. Conclusion. Based on the model, dietary advice appears to be the most cost-effective of the studied interventions. (C) 2003 American Health Foundation and Elsevier Science (USA). All rights reserved.",2003-04,21/11/2018 11:00,14/04/2020 08:34,,403-409,,4,36,,,,,,,,,,,,,,,,,,,,,1; Markov; 410,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UB55BA7G,conferencePaper,2003,"Pushkarev, O",Optimization model of the cost-effictiveness analysis in public health services,"KORUS 2003: 7TH KOREA-RUSSIA INTERNATIONAL SYMPOSIUM ON SCIENCE AND TECHNOLOGY, VOL 4, PROCEEDINGS: LIFE SCIENCE, BIOTECHNOLOGY, MEDICINE ENVIRONMENTAL TECHNOLOGY, ARCHITECTURE ENGINEERING EDUCATION SOCIAL SCIENCE",,,,,,2003,21/11/2018 11:00,14/04/2020 08:35,,69+,,,,,,,,,,,"Univ Ulsan, Res Ctr Mach Parts & Mat Proc; Tomsk Polytech Univ; Novosibirsk State Tech Univ; Ulsan Metropolitan City; Hyundai Heavy Ind Co Ltd; Univ Ulsan, Network Based Automat Res Inst; Univ Ulsan, Res Inst Basic Sci",,,,,,,,,,"

7th Korea/Russia International Symposium on Science and Technology (KORUS 2003), UNIV ULSAN, ULSAN, SOUTH KOREA, JUN 28-JUL 06, 2003

",,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JLMQUII2,conferencePaper,2002,"Koutkias, VG; Chouvarda, I; Maglaveras, N",Agent-based monitoring and alert generation for a home care telemedicine system,"AMIA 2002 SYMPOSIUM, PROCEEDINGS: BIOMEDICAL INFORMATICS: ONE DISCIPLINE",1-56053-600-4,,,,"In the present paper, a multi-agent system is proposed, which can be integrated in the home care telemedicine system that was developed in the context of the Citizen Health System (CHS) European project, functioning as a contact center for diabetic and congestive heart failure patients. The objective of the multi-agent system is to provide a set of alert/notification mechanisms for the clinicians, helping them to classify the clinical condition of each patient. Therefore, despite the huge amount of data managed by the system, due to the daily use of the contact center's services, these alert mechanisms provide the clinician with an overview of the cases that need further examination and save him/her time from the trivial cases. The multi-agent system consists of different types of agents, each one assigned with specific tasks, which communicate with each other, in order to share knowledge.",2002,21/11/2018 11:00,14/04/2020 08:34,,395-399,,,,,,,,,,,Amer Med Informat Assoc,,,,,,,,,,"

Annual Symposium of the American-Medical-Informatics-Association, San Antonio, TX, NOV 09, 2002

",,,"Humans; Systems Integration; *Telemedicine; Europe; Computer Systems; Monitoring, Physiologic/*methods; Heart Failure/therapy; *Home Care Services; Diabetes Mellitus/therapy; 110",,"Kohane, IS",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CFLG73CL,journalArticle,2002,"Albisser, AM; Hodel, AS; Albisser, JB; Wanner, A","Chronic disease management: a systems model relating outcomes, reporting, monitoring, interventions and satisfaction",CONTROL ENGINEERING PRACTICE,,0967-0661,10.1016/S0967-0661(01)00127-7,,"In health care systems, chronic disease state outcomes are typically reported as one-time observations ('snap-shots'). A novel mathematical and systems model was developed to link such reported outcomes to desired normal values. The model describes a dependency of outcomes on the characteristics of the provider, the patient and on the relative frequency of such snap-shots, thus confirming conventional methods in the traditional, chronic disease, management paradigm, Additionally, an important prediction is afforded by the model whereby, under certain conditions, outcomes can approach normal while being largely independent of the particular characteristics of either patient or provider. Exploitation of this unexpected prediction in risk assessment and managed care should be considered by health authorities. (C) 2002 Elsevier Science Ltd. All rights reserved.",2002-01,21/11/2018 11:00,14/04/2020 08:34,,101-110,,1,10,,,,,,,,,,,,,,,,,,"

4th IFAC Symposium on Modelling and Control in Biomedical Systems, KARLSBURG GREIFSWALD, GERMANY, MAR 30-APR 01, 2000

",,,System Dynamics; 1; 320,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7LVV9JL5,journalArticle,2001,"Sato, Y",Comparative analysis of health care costs in Japan and the United States: a simulation of productivity and savings behavior,JAPAN AND THE WORLD ECONOMY,,0922-1425,10.1016/S0922-1425(01)00066-4,,"Japan and the United States, though contrastive in terms of the percentage of the elderly in their population and the ratio of their health care costs to GDP, both face soaring medical expenditures. Sato et al. [Health Care Systems in Japan and the United States: A Simulation Studies and Policy Analysis. Kluwer Academic Publishers, Hingham, MA] developed a model to solve this problem by increasing the productivity of the non-health care sector. This study has applied that model to estimate national savings, and compared these savings with estimated health care costs. The results show that in order for savings to exceed expenditures the US needs to have a higher savings rate and a higher interest rate than Japan. (C) 2001 Elsevier Science B.V. All rights reserved.",2001-12,21/11/2018 11:00,14/04/2020 08:35,,429-454,,4,13,,,,,,,,,,,,,,,,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QZ3RCGUU,journalArticle,2001,"Veazie, PJ",Using computer simulation to investigate disease management,ENDOCRINOLOGIST,,1051-2144,10.1097/00019616-200105000-00008,,"Despite current efforts, the management of chronic illnesses has not been successful from a population perspective. Though research has established successful clinical practices, there is a discrepancy between the efficacy and effectiveness of these interventions. Numerous reasons are proposed for this discontinuity, including simple factors such as constraints on physician time and priorities, as well as more complex behavioral, cognitive, and organizational factors. However, these explanations describe failure independent of the process in which they occur. Knowing the short term effect of an intervention on a dynamic system of relationships provides little information regarding the evolution of the system over time. Understanding the effect of interventions on both physician practice and patient outcomes in the context of chronic disease management requires understanding the characteristics of the dynamical system as a whole. Computer simulation provides a means for such investigations. This article gives an overview of computer simulation as a methodology for exploring the ramifications of dynamic social systems on health care policy. Simulation is defined, its advantages and disadvantages are indicated, and types of model validation are discussed. A simple example of physician/patient interaction in the management of type 2 diabetes is presented for illustrative purposes.",2001-06,21/11/2018 11:00,14/04/2020 08:34,,209-216,,3,11,,,,,,,,,,,,,,,,,,,,,1; Discrete event; ?; X,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UPMRX9NC,journalArticle,2001,"Pulat, PS; Kasap, S; Splinter, GL",Simulation study of an ideal primary care delivery system,SIMULATION,,0037-5497,10.1177/003754970107600203,,"Health care delivery systems have gone through vapid changes in the last decade. As a result of these changes, researchers have conducted many studies an hospital resource planning, more specifically, on hospital bed planning. III this article, the strategic emphasis is on the primary cave bed needs in the state of Oklahoma. Unlike most studies, this study focuses ON designing an ideal primary care service delivery system, rather than evaluating the effectiveness of the current system. The state is partitioned into a minimum number of primary care service centers satisfying accessibility constraints to assure quality service. A simulation model of the system is used to determine the minimum number of primary care beds needed in the state to provide service at targeted service levels at these centers. The results of the ideal scenario will give health care managers and planners a new) perspective and help them irt making strategic planning decisions in the future.",2001-02,21/11/2018 11:00,14/04/2020 08:35,,78+,,2,76,,,,,,,,,,,,,,,,,,,,,00; ******To read; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DHHQGMYP,journalArticle,2000,"Ziv, A; Small, SD; Wolpe, PR",Patient safety and simulation-based medical education,MEDICAL TEACHER,,0142-159X,,,"Continuous quality improvement is an accepted mandate in healthcare ser vices. The delivery of the best, evidence-based quality of care ultimately depends on the competences of practitioners as well as the system that supports their work. Medical education has been increasingly called upon to insure providers possess the skills and understanding necessary to fulfill the quality mission. Patient safety has in the past five years rapidly risen to the top of the healthcare policy agenda, and been incorporated into quality initiatives. Demand for curricula in patient safety and transfer of safety lessons learned in other risky industries have created new responsibilities for medical educators. Simulation-based medical education will help fill these needs. Simulation offers ethical benefits, increased precision and relevance of training and competency assessment, and new methods of teaching error management and safety culture. Established and successful simulation methods such as standardized patients and task trainers are being joined by newer approaches enabled by improved technology.",2000-09,21/11/2018 11:00,14/04/2020 08:35,,489-495,,5,22,,,,,,,,,,,,,,,,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4BPDXC28,journalArticle,2012,"Zachariah, Rony; van Griensven, Johan",Crossing the divide: expanding the scope of operational research in Public Health Action.,Public health action,,2220-8372 2220-8372,10.5588/pha.12.0093,,,21/12/2012,21/11/2018 09:40,14/04/2020 08:35,,98,,4,2,,Public Health Action,,,,,,,,eng,,,,,,,PMID: 26392961 PMCID: PMC4463054,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LYVV74NR,journalArticle,2012,"Zhukova, T. V.; Kharagurgieva, I. M.; Svintukhovskii, O. A.",[Optimization of the health level assessment of healthy individuals in the system of primary health care in the relation with social and hygienic monitoring of population health].,Gigiena i sanitariia,,0016-9900 0016-9900,,,"It is proposed to extend the program of social and hygienic monitoring of public health by virtue of inclusion of risk factors for diseases according both to lifestyle and corresponding periodic health examination groups. Information can be obtained on the basis of materials of ""Health centers"".",2012-12,21/11/2018 09:40,14/04/2020 08:35,,21-26,,6,,,Gig Sanit,,,,,,,,rus,,,,,,,PMID: 23457987,,,,"Humans; Surveys and Questionnaires; Adult; Female; Male; Middle Aged; Young Adult; Risk Factors; Aged; Adolescent; Aged, 80 and over; Regression Analysis; Mass Screening; Age Factors; Government Regulation; Hygiene/legislation & jurisprudence/*standards; Life Style; Primary Health Care/legislation & jurisprudence/*organization & administration/standards/trends; Public Health/legislation & jurisprudence/*standards; Russia; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CLN7UHK3,journalArticle,2014,"Gulliford, Martin C.; Charlton, Judith; Bhattarai, Nawaraj; Charlton, Christopher; Rudisill, Caroline",Impact and cost-effectiveness of a universal strategy to promote physical activity in primary care: population-based cohort study and Markov model.,The European journal of health economics : HEPAC : health economics in prevention and care,,1618-7601 1618-7598,10.1007/s10198-013-0477-0,,"BACKGROUND: This study aimed to estimate the cost-effectiveness of a universal strategy to promote physical activity in primary care. METHODS: Data were analysed for a cohort of participants from the general practice research database. Empirical estimates informed a Markov model that included five long-term conditions (diabetes, coronary heart disease, stroke, colorectal cancer and depression). Simulations compared an intervention promoting physical activity in healthy adults with standard care. The intervention effect on physical activity was from a meta-analysis of randomised trials. The annual cost of intervention, in the base case, was one family practice consultation per participant year. The primary outcome was net health benefit in quality adjusted life years (QALYs). RESULTS: A cohort of 262,704 healthy participants entered the model. Intervention was associated with an increase in life years lived free from physical disease. With 5 years intervention the increase was 52 (95 % interval -11 to 115) per 1,000 participants entering the model (probability increased 91.9 %); with 10 years intervention the increase was 102 (42-164) per 1,000 (probability 99.7 %). Net health benefits at a threshold of pound30,000 per QALY were 3.2 (-11.1 to 16.9) QALYs per 1,000 participants with 5 years intervention (probability cost-effective 64.7 %) and 5.0 (-9.5 to 19.3) with 10 years intervention (probability cost-effective 72.4 %). CONCLUSIONS: A universal strategy to promote physical activity in primary care has the potential to increase life years lived free from physical disease. There is only weak evidence that a universal intervention strategy might prove cost-effective.",2014-05,21/11/2018 09:40,14/04/2020 08:34,,341-351,,4,15,,Eur J Health Econ,,,,,,,,eng,,,,,,,PMID: 23572044 PMCID: PMC3996351,,,,"Humans; Cost-Benefit Analysis; Adult; Female; Male; Middle Aged; *Quality-Adjusted Life Years; Aged; Cohort Studies; Markov Chains; Aged, 80 and over; Chronic Disease/prevention & control; *Primary Health Care; Databases, Factual; Health Promotion/*economics; 1; *Exercise; Program Evaluation/economics; Markov; 220",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, H6QBFG4S,journalArticle,2014,"Eijkenaar, Frank; van Vliet, Rene C. J. A.",Performance profiling in primary care: does the choice of statistical model matter?,Medical decision making : an international journal of the Society for Medical Decision Making,,1552-681X 0272-989X,10.1177/0272989X13498825,,"BACKGROUND: Profiling is increasingly being used to generate input for improvement efforts in health care. For these efforts to be successful, profiles must reflect true provider performance, requiring an appropriate statistical model. Sophisticated models are available to account for the specific features of performance data, but they may be difficult to use and explain to providers. OBJECTIVE: To assess the influence of the statistical model on the performance profiles of primary care providers. Data Source. Administrative data (2006-2008) on 2.8 million members of a Dutch health insurer who were registered with 1 of 4396 general practitioners. METHODS: Profiles are constructed for 6 quality measures and 5 resource use measures, controlling for differences in case mix. Models include ordinary least squares, generalized linear models, and multilevel models. Separately for each model, providers are ranked on z scores and classified as outlier if belonging to the 10% with the worst or best performance. The impact of the model is evaluated using the weighted kappa for rankings overall, percentage agreement on outlier designation, and changes in rankings over time. RESULTS: Agreement among models was relatively high overall (kappa typically .0.85). Agreement on outlier designation was more variable and often below 80%, especially for high outliers. Rankings were more similar for processes than for outcomes and expenses. Agreement among annual rankings per model was low for all models. CONCLUSIONS: Differences among models were relatively small, but the choice of statistical model did affect the rankings. In addition, most measures appear to be driven largely by chance, regardless of the model that is used. Profilers should pay careful attention to the choice of both the statistical model and the performance measures.",2014-02,21/11/2018 09:40,14/04/2020 08:34,,192-205,,2,34,,Med Decis Making,,,,,,,,eng,,,,,,,PMID: 23920433,,,,"*Quality of Health Care; Netherlands; *Models, Statistical; Primary Health Care/*organization & administration; 00; *econometric methods; *managed care; *performance measures; *profiling; *report cards; *risk adjustment; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 79TZT47E,journalArticle,2013,"Teitelbaum, April; Ba-Mancini, Abbie; Huang, Hui; Henk, Henry J.","Health care costs and resource utilization, including patient burden, associated with novel-agent-based treatment versus other therapies for multiple myeloma: findings using real-world claims data.",The oncologist,,1549-490X 1083-7159,10.1634/theoncologist.2012-0113,,"BACKGROUND: . Treatment of multiple myeloma has dramatically improved with the introduction of bortezomib (BOR), thalidomide (THAL), and lenalidomide (LEN). Studies assessing health care costs, particularly economic burden on patients, are limited. We conducted a claims-based, retrospective analysis of total health care costs as well as patient burden (patient out-of-pocket costs and number of ambulatory/hospital visits) associated with BOR/THAL/LEN treatment versus other therapies (OTHER). METHODS. Treatment episodes starting between January 1, 2005 and September 30, 2010 were identified from the claims database of a large U.S. health plan. Health care costs and utilization were measured during 1 year after initiation and analyzed per treatment episode. Multivariate analyses were used to adjust for patient characteristics, comorbidities, and line of treatment. RESULTS: A total of 4,836 treatment episodes were identified. Mean adjusted total costs were similar between BOR ($112,889) and OTHER ($111,820), but higher with THAL ($129,412) and LEN ($158,428). Mean adjusted patient out-of-pocket costs were also similar for BOR ($3,846) and OTHER ($3,900) but remained higher with THAL ($4,666) and LEN ($4,483). Mean adjusted rates of ambulatory visits were similar across therapies (BOR: 69.67; THAL: 66.31; LEN: 65.60; OTHER: 69.42). CONCLUSIONS: Adjusted analyses of real-world claims data show that total health care costs, as well as patient out-of-pocket costs, are higher with THAL/LEN treatment episodes than with BOR/OTHER therapies. Additionally, similar rates of ambulatory visits suggest that any perceived advantage in patient convenience of the orally administered drugs THAL/LEN is not supported by these data.",2013,21/11/2018 09:40,14/04/2020 08:35,,37-45,,1,18,,Oncologist,,,,,,,,eng,,,,,,,PMID: 23299776 PMCID: PMC3556254,,,,Humans; Adult; Female; Male; Middle Aged; Retrospective Studies; *Health Care Costs; Antineoplastic Agents/administration & dosage/*economics; Boronic Acids/administration & dosage; Bortezomib; Health Resources/economics; Hospitalization/economics; Multiple Myeloma/drug therapy/*economics/epidemiology; Pyrazines/administration & dosage; Thalidomide/administration & dosage/analogs & derivatives; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 68JBWUTB,journalArticle,2013,"Colussi, Claudia Flemming; Calvo, Maria Cristina Marino; Freitas, Sergio Fernando Torres de",The Linear Programming to evaluate the performance of Oral Health in Primary Care.,"Einstein (Sao Paulo, Brazil)",,2317-6385 1679-4508,,,"OBJECTIVE: To show the use of Linear Programming to evaluate the performance of Oral Health in Primary Care. METHODS: This study used data from 19 municipalities of Santa Catarina city that participated of the state evaluation in 2009 and have more than 50,000 habitants. A total of 40 indicators were evaluated, calculated using the Microsoft Excel 2007, and converted to the interval [0, 1] in ascending order (one indicating the best situation and zero indicating the worst situation). Applying the Linear Programming technique municipalities were assessed and compared among them according to performance curve named ""quality estimated frontier"". Municipalities included in the frontier were classified as excellent. Indicators were gathered, and became synthetic indicators. RESULTS: The majority of municipalities not included in the quality frontier (values different of 1.0) had lower values than 0.5, indicating poor performance. The model applied to the municipalities of Santa Catarina city assessed municipal management and local priorities rather than the goals imposed by pre-defined parameters. In the final analysis three municipalities were included in the ""perceived quality frontier"". CONCLUSION: The Linear Programming technique allowed to identify gaps that must be addressed by city managers to enhance actions taken. It also enabled to observe each municipal performance and compare results among similar municipalities.",2013-03,21/11/2018 09:40,14/04/2020 08:34,,95-101,,1,11,,Einstein (Sao Paulo),,,,,,,,por,,,,,,,PMID: 23579751 PMCID: PMC4872975,,,,"Humans; Reproducibility of Results; *Cities; Quality of Health Care/*standards; Brazil; 00; Oral Health/*standards; Primary Health Care/*standards; Programming, Linear/*standards; Reference Values; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6EFBIGHR,conferencePaper,2013,"Gow, Richard; Venugopal, Srikumar; Ray, Pradeep Kumar","The Tail Wags the Dog": A Study of Anomaly Detection in Commercial Application Performance,"2013 IEEE 21st International Symposium on Modelling, Analysis and Simulation of Computer and Telecommunication Systems",978-0-7695-5102-9,,10.1109/MASCOTS.2013.51,http://ieeexplore.ieee.org/document/6730786/,,2013-08,21/11/2018 11:46,14/04/2020 08:34,21/11/2018 11:46,355-359,,,,,,"The Tail Wags the Dog",,,,,IEEE,"San Francisco, CA, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2013 IEEE 21st International Symposium on Modelling, Analysis & Simulation of Computer and Telecommunication Systems (MASCOTS)",,,,,,,,,,,,,,, W4WBYMIC,conferencePaper,2013,,[Inaugural address & pre-conference tutorials - 4 abstracts],2013 Fifth International Conference on Advanced Computing (ICoAC),978-1-4799-3448-5 978-1-4799-3447-8,,10.1109/ICoAC.2013.6922030,http://ieeexplore.ieee.org/document/6922030/,,2013-12,21/11/2018 11:46,14/04/2020 08:35,21/11/2018 11:46,01-Apr,,,,,,,,,,,IEEE,"Chennai, India",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2013 Fifth International Conference on Advanced Computing (ICoAC),,,,,,,,,,,,,,, QCJFPHVE,conferencePaper,2016,"Sato, Hiroyuki; Yoshimura, Kazuhiro; Nakamoto, Hiroyuki; Ishibashi, Daijiro; Nakata, Yoshihiro; Yaginuma, Yoshinori; Masui, Shoichi",19.2 cm 3 flexible fetal heart rate sensor for improved quality of pregnancy life,2016 IEEE Biomedical Circuits and Systems Conference (BioCAS),978-1-5090-2959-4,,10.1109/BioCAS.2016.7833751,http://ieeexplore.ieee.org/document/7833751/,,2016-10,21/11/2018 11:47,14/04/2020 08:35,21/11/2018 11:47,140-143,,,,,,,,,,,IEEE,"Shanghai, China",,,,,,Crossref,,,,,,00; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 IEEE Biomedical Circuits and Systems Conference (BioCAS),,,,,,,,,,,,,,, YDTGQ7DY,conferencePaper,2006,"Iatrou, M.; Manjeshwar, R. M.; Ross, S. G.; Thielemans, K.; Stearns, C. W.",3D implementation of Scatter Estimation in 3D PET,2006 IEEE Nuclear Science Symposium Conference Record,978-1-4244-0560-2,,10.1109/NSSMIC.2006.354338,http://ieeexplore.ieee.org/document/4179452/,,2006,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,2142-2145,,,,,,,,,,,IEEE,"San Diego, CA, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2006 IEEE Nuclear Science Symposium Conference Record,,,,,,,,,,,,,,, WR3BGAKF,conferencePaper,2017,"Climente-Alarcon, Vicente; Arkkio, Antero; Antonino-Daviu, Jose A.",3-D simulation of a rotor suffering a bar breakage,"2017 IEEE 11th International Symposium on Diagnostics for Electrical Machines, Power Electronics and Drives (SDEMPED)",978-1-5090-0409-6,,10.1109/DEMPED.2017.8062422,http://ieeexplore.ieee.org/document/8062422/,,2017-08,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,642-648,,,,,,,,,,,IEEE,"Tinos, Greece",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2017 IEEE 11th International Symposium on Diagnostics for Electrical Machines, Power Electronics and Drives (SDEMPED)",,,,,,,,,,,,,,, 5Z5YJDJ8,journalArticle,2016,"Miao, Shun; Wang, Z. Jane; Liao, Rui",A CNN Regression Approach for Real-Time 2D/3D Registration,IEEE Transactions on Medical Imaging,,"0278-0062, 1558-254X",10.1109/TMI.2016.2521800,http://ieeexplore.ieee.org/document/7393571/,,2016-05,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,1352-1363,,5,35,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4X4GB9HS,journalArticle,2010,"Phunchongharn, Phond; Hossain, Ekram; Niyato, Dusit; Camorlinga, Sergio",A cognitive radio system for e-health applications in a hospital environment,IEEE Wireless Communications,,1536-1284,10.1109/MWC.2010.5416346,http://ieeexplore.ieee.org/document/5416346/,,2010-02,21/11/2018 11:47,14/04/2020 08:35,21/11/2018 11:47,20-28,,1,17,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5E4QVEG6,conferencePaper,2016,"Sobral, Jose V. V.; Rodrigues, Joel J. P. C.; Saleem, Kashif; de Paz, Juan F.; Corchado, Juan M.",A composite routing metric for wireless sensor networks in AAL-IoT,2016 9th IFIP Wireless and Mobile Networking Conference (WMNC),978-1-4673-8746-0,,10.1109/WMNC.2016.7543985,http://ieeexplore.ieee.org/lpdocs/epic03/wrapper.htm?arnumber=7543985,,2016-07,21/11/2018 11:47,14/04/2020 08:35,21/11/2018 11:47,168-173,,,,,,,,,,,IEEE,"Colmar, France",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 9th IFIP Wireless and Mobile Networking Conference (WMNC),,,,,,,,,,,,,,, QPFRW3PC,conferencePaper,2017,"Pan, Mingming; Tian, Shiming; Wu, Bo; Geng, Juncheng",A comprehensive weighting method for health status assessment of power distribution areas,2017 Chinese Automation Congress (CAC),978-1-5386-3524-7,,10.1109/CAC.2017.8242864,http://ieeexplore.ieee.org/document/8242864/,,2017-10,21/11/2018 11:47,14/04/2020 08:35,21/11/2018 11:47,738-742,,,,,,,,,,,IEEE,Jinan,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 Chinese Automation Congress (CAC),,,,,,,,,,,,,,, 5QJNG5DH,journalArticle,2013,"Li, Shancang; Xu, Li Da; Wang, Xinheng",A Continuous Biomedical Signal Acquisition System Based on Compressed Sensing in Body Sensor Networks,IEEE Transactions on Industrial Informatics,,"1551-3203, 1941-0050",10.1109/TII.2013.2245334,http://ieeexplore.ieee.org/document/6451260/,,2013-08,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,1764-1771,,3,9,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LQ29EFI7,conferencePaper,2017,"Laddada, S.; Benkedjouh, T.; Chaib, M. O. Si-; Drai, R.",A data-driven prognostic approach based on wavelet transform and extreme learning machine,2017 5th International Conference on Electrical Engineering - Boumerdes (ICEE-B),978-1-5386-0686-5,,10.1109/ICEE-B.2017.8192142,http://ieeexplore.ieee.org/document/8192142/,,2017-10,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,01-Apr,,,,,,,,,,,IEEE,Boumerdes,,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 5th International Conference on Electrical Engineering - Boumerdes (ICEE-B),,,,,,,,,,,,,,, XJFVET8F,conferencePaper,2016,"Mokrini, Asmae El; Benabbou, Loubna; Berrado, Abdelaziz",A decision aid process for strategic insourcing/outsourcing in a supply chain,2016 3rd International Conference on Logistics Operations Management (GOL),978-1-4673-8571-8,,10.1109/GOL.2016.7731663,http://ieeexplore.ieee.org/document/7731663/,,2016-05,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,01-Jun,,,,,,,,,,,IEEE,"Fez, Morocco",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 3rd International Conference on Logistics Operations Management (GOL),,,,,,,,,,,,,,, 7XYRWUY3,conferencePaper,2014,"Murcia, Melisa; Rivera, Maria J.; Akhavan-Tabatabaei, Raha; Sarmiento, Olga L.",A discrete-event simulation model to estimate the number of participants in the ciclovia program of Bogota,Proceedings of the Winter Simulation Conference 2014,978-1-4799-7486-3 978-1-4799-7484-9,,10.1109/WSC.2014.7020127,http://ieeexplore.ieee.org/document/7020127/,,2014-12,21/11/2018 11:47,14/04/2020 08:35,21/11/2018 11:47,2860-2871,,,,,,,,,,,IEEE,"Savanah, GA, USA",,,,,,Crossref,,,,,,1; Discrete event; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2014 Winter Simulation Conference - (WSC 2014),,,,,,,,,,,,,,, JSRNQFL6,journalArticle,2010,"Yanqing Ji; Hao Ying; Farber, Margo S; Yen, John; Dews, Peter; Miller, Richard E; Massanari, R Michael","A Distributed, Collaborative Intelligent Agent System Approach for Proactive Postmarketing Drug Safety Surveillance",IEEE Transactions on Information Technology in Biomedicine,,1089-7771,10.1109/TITB.2009.2037007,http://ieeexplore.ieee.org/document/5352275/,"Discovering unknown adverse drug reactions (ADRs) in postmarketing surveillance as early as possible is of great importance. The current approach to postmarketing surveillance primarily relies on spontaneous reporting. It is a passive surveillance system and limited by gross underreporting (<10% reporting rate), latency, and inconsistent reporting. We propose a novel team-based intelligent agent software system approach for proactively monitoring and detecting potential ADRs of interest using electronic patient records. We designed such a system and named it ADRMonitor. The intelligent agents, operating on computers located in different places, are capable of continuously and autonomously collaborating with each other and assisting the human users (e.g., the food and drug administration (FDA), drug safety professionals, and physicians). The agents should enhance current systems and accelerate early ADR identification. To evaluate the performance of the ADRMonitor with respect to the current spontaneous reporting approach, we conducted simulation experiments on identification of ADR signal pairs (i.e., potential links between drugs and apparent adverse reactions) under various conditions. The experiments involved over 275 000 simulated patients created on the basis of more than 1000 real patients treated by the drug cisapride that was on the market for seven years until its withdrawal by the FDA in 2000 due to serious ADRs. Healthcare professionals utilizing the spontaneous reporting approach and the ADRMonitor were separately simulated by decision-making models derived from a general cognitive decision model called fuzzy recognition-primed decision (RPD) model that we recently developed. The quantitative simulation results show that 1) the number of true ADR signal pairs detected by the ADRMonitor is 6.6 times higher than that by the spontaneous reporting strategy; 2) the ADR detection rate of the ADRMonitor agents with even moderate decision-making skills is five t...",2010-05,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,826-837,,3,14,,,,,,,,,,,,,,,Crossref,,,,,,00; Review,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TWK7F4AU,journalArticle,2013,Juan Cheng; Xiang Chen; Minfen Shen,A Framework for Daily Activity Monitoring and Fall Detection Based on Surface Electromyography and Accelerometer Signals,IEEE Journal of Biomedical and Health Informatics,,"2168-2194, 2168-2208",10.1109/TITB.2012.2226905,http://ieeexplore.ieee.org/document/6399498/,,2013-01,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,38-45,,1,17,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7D5YW52G,conferencePaper,2013,"Adebiyi, Marion; Oghuan, Josiah; Fatumo, Segun; Adebiyi, Ezekiel; Rasgon, Jason",A Functional Workbench for Anopheles gambiae Micro Array Analysis,2013 European Modelling Symposium,978-1-4799-2578-0 978-1-4799-2577-3,,10.1109/EMS.2013.24,http://ieeexplore.ieee.org/document/6779835/,"Insecticide resistance, a character inherited that encompasses alteration in one or more of insect's genes is now a major public health challenge combating world efforts on malaria control strategies. Anopheles has developed heavy resistance to pyrethroids, the only World Health Organization (WHO) recommended class for Indoor Residual Spray (IRS) and Long-Lasting Insecticide Treated Nets (LLITNs) through P450 pathways. We used the biochemical network of Anopheles gambiae (henceforth Ag) to deduce its resistance mechanism(s) using two expression data (when Ag is treated with pyrethroid and when controlled). The employed computational techniques are accessible by a robust, multi-faceted and friendly automated graphic user interface (GUI) tagged 'workbench' with JavaFX Scenebuilder. In this work, we introduced a computational platform to determine and also elucidate for the first time resistance mechanism to a commonly used class of insecticide, Pyrethroid. Significantly, our work is the first computational work to identify genes associated or involved in the efflux system in Ag and as a resistance mechanism in the Anopheles.",2013-11,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,138-143,,,,,,,,,,,IEEE,"Manchester, United Kingdom",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2013 European Modelling Symposium (EMS),,,,,,,,,,,,,,, XL8NBMD4,conferencePaper,2013,"Mutingi, M.; Mbohwa, C.",A fuzzy particle swarm optimization approach for task assignment in home health care,2013 IEEE International Conference on Industrial Engineering and Engineering Management,978-1-4799-0986-5,,10.1109/IEEM.2013.6962576,http://ieeexplore.ieee.org/document/6962576/,,2013-12,21/11/2018 11:47,14/04/2020 08:35,21/11/2018 11:47,1077-1081,,,,,,,,,,,IEEE,"Bangkok, Thailand",,,,,,Crossref,,,,,,1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2013 IEEE International Conference on Industrial Engineering and Engineering Management (IEEM),,,,,,,,,,,,,,, B298LD6U,conferencePaper,2015,"Yu Ting; Demirli, Kudret; Bhuiyan, Nadia",A general framework for lean transformation of hospitals,2015 International Conference on Industrial Engineering and Operations Management (IEOM),978-1-4799-6065-1,,10.1109/IEOM.2015.7093901,http://ieeexplore.ieee.org/document/7093901/,,2015-03,21/11/2018 11:47,14/04/2020 08:35,21/11/2018 11:47,01-Aug,,,,,,,,,,,IEEE,Dubai,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 International Conference on Industrial Engineering and Operations Management (IEOM),,,,,,,,,,,,,,, SBPERPWS,conferencePaper,2016,"Chen, Gaige; Chen, Jinglong; Zi, Yanyang",A GKPCA-NHSMM based methodology for accurate RUL prognostics of nonlinear mechanical system with multistate deterioration,2016 Prognostics and System Health Management Conference (PHM-Chengdu),978-1-5090-2778-1,,10.1109/PHM.2016.7819782,http://ieeexplore.ieee.org/document/7819782/,,2016-10,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,01-May,,,,,,,,,,,IEEE,"Chengdu, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 Prognostics and System Health Management Conference (PHM-Chengdu),,,,,,,,,,,,,,, 7PIPAL46,conferencePaper,2007,"Biswas, Gautam; Mahadevan, Sankaran",A Hierarchical Model-based approach to Systems Health Management,2007 IEEE Aerospace Conference,978-1-4244-0524-4,,10.1109/AERO.2007.352943,http://ieeexplore.ieee.org/document/4161681/,"Integrated Systems Health Management (ISHM) provides the ability to maintain system health and performance over the life of a system. For safety-critical systems, ISHM must maintain safe operations while increasing availability by preserving functionality and minimizing downtime. This paper discusses a model-based approach to ISHM that combines fault detection, isolation and identification, fault-adaptive control, and prognosis into a common framework. At the core of this framework are a set of component oriented physical system models. By incorporating physics of failure models into component models the dynamic behavior of a failing or degrading system can be derived by simulation. Current state information predicts future behavior and performance of the system to guide decision making on system operation and maintenance. We demonstrate our approach on the fluid loop of a secondary sodium cooling loop of a nuclear reactor system. We model the fluid loop at the system level and a generic pump system at the component level. Monitoring and diagnosis at the system level may point to faults and degradation in components, e.g., the pump. A more detailed analysis of the pump using structural and material models may point to physics of failure models that explain degradation in the pump components. This information can form the basis for prognostic analysis that forms the core methodology for monitoring system performance and decision making for maintenance.",2007,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,Jan-14,,,,,,,,,,,IEEE,"Big Sky, MT, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2007 IEEE Aerospace Conference,,,,,,,,,,,,,,, 7HS3RDNY,conferencePaper,2012,Chao Yang; Jiannong Cao; Xuefeng Liu; Lijun Chen; Daoxu Chen,A high quality event capture scheme for WSN-based structural health monitoring,2012 IEEE Global Communications Conference (GLOBECOM),978-1-4673-0921-9 978-1-4673-0920-2 978-1-4673-0919-6,,10.1109/GLOCOM.2012.6503182,http://ieeexplore.ieee.org/document/6503182/,,2012-12,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,622-627,,,,,,,,,,,IEEE,"Anaheim, CA, USA",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GLOBECOM 2012 - 2012 IEEE Global Communications Conference,,,,,,,,,,,,,,, TCP4BRST,conferencePaper,2013,"Balouchestani, Mohammadreza; Raahemifar, Kaainran; Krishnan, Sridhar",A high reliability detection algorithm for wireless ECG systems based on compressed sensing theory,2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC),978-1-4577-0216-7,,10.1109/EMBC.2013.6610602,http://ieeexplore.ieee.org/document/6610602/,,2013-07,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,4722-4725,,,,,,,,,,,IEEE,Osaka,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC),,,,,,,,,,,,,,, ZBVFA5KD,conferencePaper,2018,"Elalouf, Amir; Tsadikovich, Dmitry; Levner, Eugene",A location-routing problem within blood sample collection chains,"2018 5th International Conference on Control, Decision and Information Technologies (CoDIT)",978-1-5386-5065-3,,10.1109/CoDIT.2018.8394826,https://ieeexplore.ieee.org/document/8394826/,,2018-04,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,488-491,,,,,,,,,,,IEEE,Thessaloniki,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2018 5th International Conference on Control, Decision and Information Technologies (CoDIT)",,,,,,,,,,,,,,, VSUHHPF5,conferencePaper,2012,"Sunghoon Ivan Lee; Ling, Charles; Nahapetian, Ani; Sarrafzadeh, Majid",A mechanism for data quality estimation of on-body cardiac sensor networks,2012 IEEE Consumer Communications and Networking Conference (CCNC),978-1-4577-2071-0 978-1-4577-2070-3 978-1-4577-2069-7,,10.1109/CCNC.2012.6181085,http://ieeexplore.ieee.org/document/6181085/,,2012-01,21/11/2018 11:47,14/04/2020 08:35,21/11/2018 11:47,194-198,,,,,,,,,,,IEEE,"Las Vegas, NV, USA",,,,,,Crossref,,,,,,00; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 IEEE Consumer Communications and Networking Conference (CCNC),,,,,,,,,,,,,,, CYCFLB8S,journalArticle,2011,"Kang, Kyungtae; Park, Kyung-Joon; Song, Jae-Jin; Yoon, Chang-Hwan; Sha, Lui",A Medical-Grade Wireless Architecture for Remote Electrocardiography,IEEE Transactions on Information Technology in Biomedicine,,"1089-7771, 1558-0032",10.1109/TITB.2011.2104365,http://ieeexplore.ieee.org/document/5682049/,,2011-03,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,260-267,,2,15,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RB95SHBD,journalArticle,2008,"Spyrou, S.; Bamidis, P.D.; Maglaveras, N.; Pangalos, G.; Pappas, C.",A Methodology for Reliability Analysis in Health Networks,IEEE Transactions on Information Technology in Biomedicine,,1089-7771,10.1109/TITB.2007.905125,http://ieeexplore.ieee.org/document/4358906/,,2008-05,21/11/2018 11:47,14/04/2020 08:35,21/11/2018 11:47,377-386,,3,12,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XUFW7VX8,conferencePaper,2004,"Datta, K.; Squires, D.; Sverdrup, J.",A methodology to quantify some IVHM requirements during RLV conceptual design,"Annual Symposium Reliability and Maintainability, 2004 - RAMS",978-0-7803-8215-2,,10.1109/RAMS.2004.1285495,http://ieeexplore.ieee.org/document/1285495/,,2004,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,485-491,,,,,,,,,,,IEEE,"Los Angeles, CA, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Annual Symposium Reliability and Maintainability, 2004 - RAMS",,,,,,,,,,,,,,, SY3ISZQH,journalArticle,2017,"Liu, Xiong Ying; Wu, Ze Tao; Fan, Yi; Tentzeris, Emmanouil M.",A Miniaturized CSRR Loaded Wide-Beamwidth Circularly Polarized Implantable Antenna for Subcutaneous Real-Time Glucose Monitoring,IEEE Antennas and Wireless Propagation Letters,,"1536-1225, 1548-5757",10.1109/LAWP.2016.2590477,http://ieeexplore.ieee.org/document/7509619/,,2017,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,577-580,,,16,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HISTLNA5,conferencePaper,2012,"Moungla, Hassine; Touati, Nora; Salem, Osman; Mehaoua, Ahmed",A Min-Max multi-commodity flow model for wireless body area networks routing,2012 IEEE Consumer Communications and Networking Conference (CCNC),978-1-4577-2071-0 978-1-4577-2070-3 978-1-4577-2069-7,,10.1109/CCNC.2012.6180996,http://ieeexplore.ieee.org/document/6180996/,,2012-01,21/11/2018 11:47,14/04/2020 08:35,21/11/2018 11:47,424-428,,,,,,,,,,,IEEE,"Las Vegas, NV, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 IEEE Consumer Communications and Networking Conference (CCNC),,,,,,,,,,,,,,, RZ2993S5,conferencePaper,2014,"Ribeiro, Reiga R.; Feitosa, Allan R. S.; de Souza, Ricardo E.; dos Santos, Wellington P.",A modified differential evolution algorithm for the reconstruction of electrical impedance tomography images,5th ISSNIP-IEEE Biosignals and Biorobotics Conference (2014): Biosignals and Robotics for Better and Safer Living (BRC),978-1-4799-5689-0 978-1-4799-5688-3,,10.1109/BRC.2014.6880982,http://ieeexplore.ieee.org/document/6880982/,,2014-05,21/11/2018 11:47,14/04/2020 08:35,21/11/2018 11:47,01-Jun,,,,,,,,,,,IEEE,"Salvador, Brazil",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,5th IEEE Biosignals and Biorobotics conference (BRC 2014),,,,,,,,,,,,,,, 28ZR4LL9,conferencePaper,2013,"Liu, Huashu; Ma, Lin; Gu, Yuantong",A Monte-Carlo simulation method for industry transformer health prediction based on dissolved gas analysis,"2013 International Conference on Quality, Reliability, Risk, Maintenance, and Safety Engineering (QR2MSE)",978-1-4799-1016-8 978-1-4799-1014-4,,10.1109/QR2MSE.2013.6625898,http://ieeexplore.ieee.org/document/6625898/,"Industry transformer condition monitoring techniques are widely used by the power utilities for condition assessment of oil-paper insulation systems on industry transformers. Among existings monitoring methods, dissolved gas analysis (DGA) is one of the most commonly used techniques in power industry. Various diagnostic models have been developed based on DGA to identify the fault types of industry transformers. However, transformer health prediction is also significant in industry. Therefore, we mainly focus on the time series health prediction of industry transformers based on DGA technique in this paper. Monte-Carlo (MC) simulation is conducted based on DGA method to estimate time series reliability of industry transformers. According to our reliability evaluation, the failure probability of industry transformers will increase with respect to age without proper maintenance.",2013-07,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,1673-1676,,,,,,,,,,,IEEE,"Chengdu, China",,,,,,Crossref,,,,,,1; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2013 International Conference on Quality, Reliability, Risk, Maintenance, and Safety Engineering (QR2MSE)",,,,,,,,,,,,,,, 3IGQ4MFW,journalArticle,2010,"Olesen, Oline Vinter; Svarer, Claus; Sibomana, Merence; Keller, Sune H.; Holm, Søren; Jensen, Jørgen A.; Andersen, Flemming; Højgaard, Liselotte",A Movable Phantom Design for Quantitative Evaluation of Motion Correction Studies on High Resolution PET Scanners,IEEE Transactions on Nuclear Science,,"0018-9499, 1558-1578",10.1109/TNS.2010.2043369,http://ieeexplore.ieee.org/document/5485119/,,2010-06,21/11/2018 11:47,14/04/2020 08:35,21/11/2018 11:47,1116-1124,,3,57,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GMWB9WQ2,conferencePaper,2013,"Ye, Yun; Ci, Song; Katsaggelos, Aggelos K.; Liu, Yanwei",A multi-camera motion capture system for remote healthcare monitoring,2013 IEEE International Conference on Multimedia and Expo (ICME),978-1-4799-0015-2,,10.1109/ICME.2013.6607566,http://ieeexplore.ieee.org/document/6607566/,,2013-07,21/11/2018 11:47,14/04/2020 08:35,21/11/2018 11:47,01-Jun,,,,,,,,,,,IEEE,"San Jose, CA, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2013 IEEE International Conference on Multimedia and Expo (ICME),,,,,,,,,,,,,,, CSRS47MM,conferencePaper,2017,"Xie, Tao; Chen, Yiqiang; Hu, Lisha; Gao, Chenlong; Hu, Chunyu; Shen, Jianfei",A multistage collaborative filtering method for fall detection,2017 International Joint Conference on Neural Networks (IJCNN),978-1-5090-6182-2,,10.1109/IJCNN.2017.7966277,http://ieeexplore.ieee.org/document/7966277/,,2017-05,21/11/2018 11:47,14/04/2020 08:35,21/11/2018 11:47,3355-3362,,,,,,,,,,,IEEE,"Anchorage, AK, USA",,,,,,Crossref,,,,,,1; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 International Joint Conference on Neural Networks (IJCNN),,,,,,,,,,,,,,, VQ74L7FT,conferencePaper,2015,Xiu Li; Jingdong Song,A New ANN-Markov chain methodology for water quality prediction,2015 International Joint Conference on Neural Networks (IJCNN),978-1-4799-1960-4,,10.1109/IJCNN.2015.7280320,http://ieeexplore.ieee.org/document/7280320/,,2015-07,21/11/2018 11:47,14/04/2020 08:35,21/11/2018 11:47,01-Jun,,,,,,,,,,,IEEE,"Killarney, Ireland",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 International Joint Conference on Neural Networks (IJCNN),,,,,,,,,,,,,,, SH2AD82P,conferencePaper,2016,"Issaoui, Brahim; Zidi, Issam; Ghedira, Khaled",A new metaheuristic for the Home Health Care Problem: Caregivers tours and conflict visits,"2016 IEEE International Conference on Systems, Man, and Cybernetics (SMC)",978-1-5090-1897-0,,10.1109/SMC.2016.7844755,http://ieeexplore.ieee.org/document/7844755/,"In this paper, we try to improve health care services by treating the variation among several issues related to the health field, particularly the Home Health Care Problem (HHCP). In fact, Home Health Care Service (HHCS) is known as a care mode allowing patients who suffer from complex and evolving diseases to benefit at home from medical and paramedical coordinated care that can be only provided in hospitals. In this work, we treat the Caregivers' Tours Problem (CTP) and conflict management sanitary visits to patients' homes. We developed a new three-phase metaheuristic, which optimizes both the daily caregivers' tours to minimize the travel costs and maximizes the planned services in order to address potential conflicts. The obtained numerical results, compared with those provided by the other existing approaches, are motivating and encouraging.",2016-10,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,003374-003380,,,,,,A new metaheuristic for the Home Health Care Problem,,,,,IEEE,"Budapest, Hungary",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2016 IEEE International Conference on Systems, Man, and Cybernetics (SMC)",,,,,,,,,,,,,,, LE6C94S2,conferencePaper,2013,"Rabbani, Masoud; Pakzad, Farhang; Kazemi, Seyed Mahmood",A new modelling for p-hub median problem by considering flow-dependent costs,"2013 5th International Conference on Modeling, Simulation and Applied Optimization (ICMSAO)",978-1-4673-5814-9 978-1-4673-5812-5 978-1-4673-5813-2,,10.1109/ICMSAO.2013.6552582,http://ieeexplore.ieee.org/document/6552582/,,2013-04,21/11/2018 11:47,14/04/2020 08:35,21/11/2018 11:47,01-Apr,,,,,,,,,,,IEEE,Hammamet,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2013 5th International Conference on Modeling, Simulation and Applied Optimization (ICMSAO 2013)",,,,,,,,,,,,,,, J35ZZ64Q,conferencePaper,2011,"Kannoju, Praveen Kumar; Sridhar, K. V.; Prasad, K. S. R.",A New Paradigm of Electronic Health Record for Efficient Implementation of Health Care Delivery,"2011 Second International Conference on Intelligent Systems, Modelling and Simulation",978-1-4244-9809-3,,10.1109/ISMS.2011.28,http://ieeexplore.ieee.org/document/5730331/,"A radical change in technical approach is needed to achieve electronic records suitable to support an engineered system of healthcare at rural and isolated areas. The challenges that have to be faced to achieve this change are improve patient safety, improve the quality and efficiency of patient care, and reduce healthcare delivery costs at rural areas. Electronic Health record (EHR) is a much anticipated solution for this problem which gives a true lifetime, person centered medical record of a patient. This paper introduces the innovative concept of developing an efficient EHR in a way that effectively implements the creation, updation, maintenance, representation and transmission of the medical data. In this implementation, the static information such as identification details, lifestyle habits, etc will remain in the database and only the dynamic data such as the rapidly changing health status of the patient along with the graphical and real-time data such as cardiograph signals, pathological reports are modified from episode to episode and can be sent using proper transmission media to the nearest Expert Centre for immediate diagnosis. The vital data which needs to be transmitted is compressed using the suitable and efficient compression technique for reducing the time of transmission.",2011-01,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,118-120,,,,,,,,,,,IEEE,"Phnom Penh, Cambodia",,,,,,Crossref,,,,,,00; 100; 120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2011 2nd International Conference on Intelligent Systems, Modelling and Simulation (ISMS)",,,,,,,,,,,,,,, FK9YE7SE,conferencePaper,2012,"Buckley, J.; O'Flynn, B.; Loizou, L.; Haigh, P.; Boyle, D.; Angove, P.; Barton, J.; Popovici, C. O'Mathuna. E.; O'Connell, S.",A Novel and Miniaturized 433/868MHz Multi-band Wireless Sensor Platform for Body Sensor Network Applications,2012 Ninth International Conference on Wearable and Implantable Body Sensor Networks,978-0-7695-4698-8 978-1-4673-1393-3,,10.1109/BSN.2012.6,http://ieeexplore.ieee.org/document/6200530/,,2012-05,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,63-66,,,,,,,,,,,IEEE,"London, United Kingdom",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 Ninth International Conference on Wearable and Implantable Body Sensor Networks (BSN),,,,,,,,,,,,,,, GWNESN8A,conferencePaper,2016,"Kitzig, Andreas; Naroska, Edwin; Stockmanns, Gudrun; Viga, Reinhard; Grabmaier, Anton",A novel approach to creating artificial training and test data for an HMM based posture recognition system,2016 IEEE 26th International Workshop on Machine Learning for Signal Processing (MLSP),978-1-5090-0746-2,,10.1109/MLSP.2016.7738879,http://ieeexplore.ieee.org/document/7738879/,,2016-09,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,01-Jun,,,,,,,,,,,IEEE,"Vietri sul Mare, Salerno, Italy",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 IEEE 26th International Workshop on Machine Learning for Signal Processing (MLSP),,,,,,,,,,,,,,, 5PFTHC8F,journalArticle,2016,"Yaakob, Naimah; Khalil, Ibrahim",A Novel Congestion Avoidance Technique for Simultaneous Real-Time Medical Data Transmission,IEEE Journal of Biomedical and Health Informatics,,"2168-2194, 2168-2208",10.1109/JBHI.2015.2406884,http://ieeexplore.ieee.org/document/7047809/,,2016-03,21/11/2018 11:47,14/04/2020 08:35,21/11/2018 11:47,669-681,,2,20,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XRSG7SID,conferencePaper,2010,"Yaghmaee Moghaddam, Mohammad Hossien; Adjeroh, Donald",A Novel Congestion Control Protocol for Vital Signs Monitoring in Wireless Biomedical Sensor Networks,2010 IEEE Wireless Communication and Networking Conference,978-1-4244-6396-1,,10.1109/WCNC.2010.5506650,http://ieeexplore.ieee.org/document/5506650/,,2010-04,21/11/2018 11:47,14/04/2020 08:35,21/11/2018 11:47,01-Jun,,,,,,,,,,,IEEE,"Sydney, Australia",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Networking Conference (WCNC),,,,,,,,,,,,,,, CGR4KR65,journalArticle,2015,"Akay, Altug; Dragomir, Andrei; Erlandsson, Bjorn-Erik",A Novel Data-Mining Approach Leveraging Social Media to Monitor Consumer Opinion of Sitagliptin,IEEE Journal of Biomedical and Health Informatics,,"2168-2194, 2168-2208",10.1109/JBHI.2013.2295834,http://ieeexplore.ieee.org/document/6691899/,,2015-01,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,389-396,,1,19,,,,,,,,,,,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LKK2CTFN,conferencePaper,2016,"Fourati, Hend; Idoudi, Hanen; Saidane, Leila Azouz",A novel IEEE 802.15.6 CSMA/CA service differentiation,2016 IEEE/ACS 13th International Conference of Computer Systems and Applications (AICCSA),978-1-5090-4320-0,,10.1109/AICCSA.2016.7945686,http://ieeexplore.ieee.org/document/7945686/,,2016-11,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,01-Jul,,,,,,,,,,,IEEE,"Agadir, Morocco",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 IEEE/ACS 13th International Conference of Computer Systems and Applications (AICCSA),,,,,,,,,,,,,,, Q952SVQM,conferencePaper,2017,"Kunnappilly, Ashalatha; Sorici, Alexandru; Awada, Imad Alex; Mocanu, Irina; Seceleanu, Cristina; Florea, Adina Madga",A Novel Integrated Architecture for Ambient Assisted Living Systems,2017 IEEE 41st Annual Computer Software and Applications Conference (COMPSAC),978-1-5386-0367-3,,10.1109/COMPSAC.2017.28,http://ieeexplore.ieee.org/document/8029645/,,2017-07,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,465-472,,,,,,,,,,,IEEE,Turin,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 IEEE 41st Annual Computer Software and Applications Conference (COMPSAC),,,,,,,,,,,,,,, UMKV42JL,journalArticle,2018,"Ji, Qing; Ding, Zhi; Wang, Ning; Pan, Miao; Song, Gangbing",A Novel Waveform Optimization Scheme for Piezoelectric Sensors Wire-Free Charging in the Tightly Insulated Environment,IEEE Internet of Things Journal,,2327-4662,10.1109/JIOT.2018.2817601,https://ieeexplore.ieee.org/document/8320773/,,2018-06,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,1936-1946,,3,5,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, M3QDR4T5,conferencePaper,2009,"Araz, Ozgur M.; Fowler, John W.; Lant, Tim W.; Jehn, Megan",A pandemic influenza simulation model for preparedness planning,Proceedings of the 2009 Winter Simulation Conference (WSC),978-1-4244-5770-0,,10.1109/WSC.2009.5429732,http://ieeexplore.ieee.org/document/5429732/,,2009-12,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,1986-1995,,,,,,,,,,,IEEE,"Austin, TX, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2009 Winter Simulation Conference - (WSC 2009),,,,,,,,,,,,,,, SZBTAMEI,conferencePaper,2017,"Wang, Xiaotian",A particle filtering approach for aircraft structure life prediction,2017 Prognostics and System Health Management Conference (PHM-Harbin),978-1-5386-0370-3,,10.1109/PHM.2017.8079255,http://ieeexplore.ieee.org/document/8079255/,,2017-07,21/11/2018 11:47,14/04/2020 08:35,21/11/2018 11:47,01-May,,,,,,,,,,,IEEE,"Harbin, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 Prognostics and System Health Management Conference (PHM-Harbin),,,,,,,,,,,,,,, 9BQRPJVC,conferencePaper,2011,"Ostadabbas, S.; Yousefi, R.; Nourani, M.; Faezipour, M.; Tamil, L.; Pompeo, M.",A Posture Scheduling Algorithm Using Constrained Shortest Path to Prevent Pressure Ulcers,2011 IEEE International Conference on Bioinformatics and Biomedicine,978-1-4577-1799-4,,10.1109/BIBM.2011.24,http://ieeexplore.ieee.org/document/6120461/,,2011-11,21/11/2018 11:47,14/04/2020 08:35,21/11/2018 11:47,327-332,,,,,,,,,,,IEEE,"Atlanta, GA, USA",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2011 IEEE International Conference on Bioinformatics and Biomedicine (BIBM),,,,,,,,,,,,,,, BCQLECDW,conferencePaper,2000,"Smith, P.A.; Campbell, D.V.",A practical implementation of BICS for safety-critical applications,Proceedings 2000 IEEE International Workshop on Defect Based Testing (Cat. No.PR00637),978-0-7695-0637-1,,10.1109/DBT.2000.843690,http://ieeexplore.ieee.org/document/843690/,,2000,21/11/2018 11:47,14/04/2020 08:35,21/11/2018 11:47,51-56,,,,,,,,,,,IEEE Comput. Soc,"Montreal, Que., Canada",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2000 IEEE International Workshop on Defect Based Testing,,,,,,,,,,,,,,, J44UC6P3,conferencePaper,2016,"Huang, Qiang; Su, Haixia; Wang, Jian; Huang, Weixing; Zhang, Guigang; Huang, Jiayang",A prediction method for aero-engine health management based on nonlinear time series analysis,2016 IEEE International Conference on Prognostics and Health Management (ICPHM),978-1-5090-0382-2,,10.1109/ICPHM.2016.7542816,http://ieeexplore.ieee.org/document/7542816/,,2016-06,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,01-Aug,,,,,,,,,,,IEEE,"Ottawa, ON, Canada",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 IEEE International Conference on Prognostics and Health Management (ICPHM),,,,,,,,,,,,,,, BD9UWR5Q,journalArticle,2017,"Yi, Changyan; Cai, Jun",A Priority-Aware Truthful Mechanism for Supporting Multi-Class Delay-Sensitive Medical Packet Transmissions in E-Health Networks,IEEE Transactions on Mobile Computing,,1536-1233,10.1109/TMC.2016.2628034,http://ieeexplore.ieee.org/document/7742338/,,01/09/2017,21/11/2018 11:47,14/04/2020 08:35,21/11/2018 11:47,2422-2435,,9,16,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, L9BRWBVE,conferencePaper,2016,"Manirabona, Audace; Boudjit, Saadi; Fourati, Lamia Chaari",A Priority-Weighted Round Robin scheduling strategy for a WBAN based healthcare monitoring system,2016 13th IEEE Annual Consumer Communications & Networking Conference (CCNC),978-1-4673-9292-1,,10.1109/CCNC.2016.7444760,http://ieeexplore.ieee.org/document/7444760/,,2016-01,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,224-229,,,,,,,,,,,IEEE,"Las Vegas, NV",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 13th IEEE Annual Consumer Communications & Networking Conference (CCNC),,,,,,,,,,,,,,, RMWPG72K,conferencePaper,2007,"Greene, Marjorie; Eek, Robert",A public health application of data analysis for homeland security,2007 Winter Simulation Conference,978-1-4244-1305-8 978-1-4244-1306-5,,10.1109/WSC.2007.4419719,http://ieeexplore.ieee.org/document/4419719/,,2007-12,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,1177-1179,,,,,,,,,,,IEEE,"Washington, DC, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2007 Winter Simulation Conference,,,,,,,,,,,,,,, LBFU42U9,conferencePaper,2017,"Kim, Taesic; Adhikaree, Amit; Kang, Daewook; Kim, Myoungho; Oh, Chang-Yeol; Baek, Juwon",A real-time condition monitoring for lithium-ion batteries using a low-price microcontroller,2017 IEEE Energy Conversion Congress and Exposition (ECCE),978-1-5090-2998-3,,10.1109/ECCE.2017.8096881,http://ieeexplore.ieee.org/document/8096881/,,2017-10,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,5248-5253,,,,,,,,,,,IEEE,"Cincinnati, OH",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 IEEE Energy Conversion Congress and Exposition (ECCE),,,,,,,,,,,,,,, STSLPT8Y,conferencePaper,2016,"Khemapech, Ittipong; Sansrimahachai, Watsawee; Toahchoodee, Manachai",A real-time Health Monitoring and warning system for bridge structures,2016 IEEE Region 10 Conference (TENCON),978-1-5090-2597-8,,10.1109/TENCON.2016.7848598,http://ieeexplore.ieee.org/document/7848598/,,2016-11,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,3010-3013,,,,,,,,,,,IEEE,Singapore,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,TENCON 2016 - 2016 IEEE Region 10 Conference,,,,,,,,,,,,,,, 5ARS8PHW,conferencePaper,2015,"Singh, Shashi Raj; Jayasuriya, Janaka; Zhou, Chongyu; Motani, Mehul",A RESTful web networking framework for vital sign monitoring,2015 IEEE International Conference on Communications (ICC),978-1-4673-6432-4,,10.1109/ICC.2015.7248375,http://ieeexplore.ieee.org/document/7248375/,,2015-06,21/11/2018 11:47,14/04/2020 08:35,21/11/2018 11:47,524-529,,,,,,,,,,,IEEE,London,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 IEEE International Conference on Signal Processing for Communications (ICC),,,,,,,,,,,,,,, 4JX46WPD,conferencePaper,2011,"Jangde, Priyanka; Mishra, Durgesh Kumar",A Secure Multiparty Computation Solution to Healthcare Frauds and Abuses,"2011 Second International Conference on Intelligent Systems, Modelling and Simulation",978-1-4244-9809-3,,10.1109/ISMS.2011.75,http://ieeexplore.ieee.org/document/5730336/,,2011-01,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,139-142,,,,,,,,,,,IEEE,"Phnom Penh, Cambodia",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2011 2nd International Conference on Intelligent Systems, Modelling and Simulation (ISMS)",,,,,,,,,,,,,,, W46TZ2DU,conferencePaper,2012,"Grosso, J.M.; Ocampo-Martinez, C.; Puig, V.",A service reliability model predictive control with dynamic safety stocks and actuators health monitoring for drinking water networks,2012 IEEE 51st IEEE Conference on Decision and Control (CDC),978-1-4673-2066-5 978-1-4673-2065-8 978-1-4673-2063-4 978-1-4673-2064-1,,10.1109/CDC.2012.6426036,http://ieeexplore.ieee.org/document/6426036/,,2012-12,21/11/2018 11:47,14/04/2020 08:34,21/11/2018 11:47,4568-4573,,,,,,,,,,,IEEE,"Maui, HI, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 IEEE 51st Annual Conference on Decision and Control (CDC),,,,,,,,,,,,,,, MR6DWCBQ,conferencePaper,2013,Qian Zheng; Min Chen; Anpeng Huang; Bingli Jiao; Linzhen Xie,A Service-oriented Self-adaptive CCE (S2-CCE) configuration mechanism to enhance time-sensitive mHealth applications,2013 IEEE Global Communications Conference (GLOBECOM),978-1-4799-1353-4,,10.1109/GLOCOM.2013.6831490,http://ieeexplore.ieee.org/document/6831490/,,2013-12,21/11/2018 11:47,14/04/2020 08:35,21/11/2018 11:47,2749-2754,,,,,,,,,,,IEEE,"Atlanta, GA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2013 IEEE Global Communications Conference (GLOBECOM 2013),,,,,,,,,,,,,,, VKJHQN3E,conferencePaper,2012,"Duan, Pengfei; de Haag, Maarten Uijt",A simulation environment for evaluation of Integrated Alerting and Notification (IAN) concepts,2012 IEEE/AIAA 31st Digital Avionics Systems Conference (DASC),978-1-4673-1699-6 978-1-4673-1700-9,,10.1109/DASC.2012.6382298,http://ieeexplore.ieee.org/document/6382298/,,2012-10,21/11/2018 11:48,14/04/2020 08:34,21/11/2018 11:48,2E4-1-2E4-12,,,,,,,,,,,IEEE,"Williamsburg, VA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 IEEE/AIAA 31st Digital Avionics Systems Conference (DASC),,,,,,,,,,,,,,, IH5JI9I2,conferencePaper,2017,"Kadarla, Kavitha; Sharma, S.C.; Bhardwaj, Tushar; Chaudhary, Ajay",A Simulation Study of Response Times in Cloud Environment for IoT-Based Healthcare Workloads,2017 IEEE 14th International Conference on Mobile Ad Hoc and Sensor Systems (MASS),978-1-5386-2324-4,,10.1109/MASS.2017.65,http://ieeexplore.ieee.org/document/8108820/,,2017-10,21/11/2018 11:48,14/04/2020 08:34,21/11/2018 11:48,678-683,,,,,,,,,,,IEEE,"Orlando, FL",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 IEEE 14th International Conference on Mobile Ad-Hoc and Sensor Systems (MASS),,,,,,,,,,,,,,, RHYR9WW2,conferencePaper,2002,"Ramis, F.J.; Palma, J.L.; Estrada, V.F.; Coscolla, G.",A simulator to improve patient's service in a network of clinic laboratories,Proceedings of the Winter Simulation Conference,978-0-7803-7614-4,,10.1109/WSC.2002.1166416,http://ieeexplore.ieee.org/document/1166416/,,2002,21/11/2018 11:48,14/04/2020 08:35,21/11/2018 11:48,1444-1447,,,2,,,,,,,,IEEE,"San Diego, CA, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2002 Winter Simulation Conference,,,,,,,,,,,,,,, LM3EU7LC,conferencePaper,2016,"Wu, Chia-Tung; Tzeng, Yu-Fen; Ho, Te-Wei; Chen, Shyh-Wei; Gau, Bih-Shya; Lai, Feipei; Chiu, Hung-Yu",A smart phone application in improving healthy lifestyles and health outcomes for school-age children with asthma,2016 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining (ASONAM),978-1-5090-2846-7,,10.1109/ASONAM.2016.7752368,http://ieeexplore.ieee.org/document/7752368/,,2016-08,21/11/2018 11:48,14/04/2020 08:35,21/11/2018 11:48,1034-1037,,,,,,,,,,,IEEE,"San Francisco, CA, USA",,,,,,Crossref,,,,,,asthma; healthy lifestyles; smart phone application; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining (ASONAM),,,,,,,,,,,,,,, CWH369CD,conferencePaper,2012,"Vohra, Aliabbas; Sarkar, Mahasweta; Lee, Gordon",A smart transmission scheme for emergency data from a network of bio-sensors on the human body,2012 IEEE International Conference on Multisensor Fusion and Integration for Intelligent Systems (MFI),978-1-4673-2512-7 978-1-4673-2510-3 978-1-4673-2511-0,,10.1109/MFI.2012.6343064,http://ieeexplore.ieee.org/document/6343064/,,2012-09,21/11/2018 11:48,14/04/2020 08:35,21/11/2018 11:48,200-205,,,,,,,,,,,IEEE,"Hamburg, Germany",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 IEEE International Conference on Multisensor Fusion and Integration for Intelligent Systems (MFI 2012),,,,,,,,,,,,,,, FBLP3NZ2,conferencePaper,2014,"Shih, Yuan-Kang; Wei, Hung-Yu",A Soft Fault Detection Mechanism with High Accuracy on Machine-to-Machine Communication Networks,"2014 IEEE International Conference on Internet of Things(iThings), and IEEE Green Computing and Communications (GreenCom) and IEEE Cyber, Physical and Social Computing (CPSCom)",978-1-4799-5967-9,,10.1109/iThings.2014.63,http://ieeexplore.ieee.org/document/7059688/,,2014-09,21/11/2018 11:48,14/04/2020 08:35,21/11/2018 11:48,340-343,,,,,,,,,,,IEEE,"Taipei, Taiwan",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2014 IEEE International Conference on Internet of Things(iThings), and IEEE Green Computing and Communications (GreenCom) and IEEE Cyber, Physical and Social Computing(CPSCom)",,,,,,,,,,,,,,, EMAABM2Y,conferencePaper,2018,"Arfaoui, Amel; ben Letaifa, Asma; Kribeche, Ali; Senouci, Sidi Mohammed; Hamdi, Mohamed",A stochastic game for adaptive security in constrained wireless body area networks,2018 15th IEEE Annual Consumer Communications & Networking Conference (CCNC),978-1-5386-4790-5,,10.1109/CCNC.2018.8319222,http://ieeexplore.ieee.org/document/8319222/,,2018-01,21/11/2018 11:48,14/04/2020 08:34,21/11/2018 11:48,01-Jul,,,,,,,,,,,IEEE,"Las Vegas, NV",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2018 15th IEEE Annual Consumer Communications & Networking Conference (CCNC),,,,,,,,,,,,,,, CCM7B5K2,conferencePaper,2014,"Shih, Yuan-Yao; Pang, Ai-Chun; Hsiu, Pi-Cheng",A storage-free data parasitizing scheme for wireless body area networks,2014 IFIP Networking Conference,978-3-901882-58-6,,10.1109/IFIPNetworking.2014.6857085,http://ieeexplore.ieee.org/document/6857085/,,2014-06,21/11/2018 11:48,14/04/2020 08:35,21/11/2018 11:48,01-Sep,,,,,,,,,,,IEEE,"Trondheim, Norway",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2014 IFIP Networking Conference,,,,,,,,,,,,,,, I4JSTC5J,journalArticle,2018,"He, Yongfu; Peng, Yu; Wang, Shaojun; Liu, Datong; Leong, Philip H. W.",A Structured Sparse Subspace Learning Algorithm for Anomaly Detection in UAV Flight Data,IEEE Transactions on Instrumentation and Measurement,,"0018-9456, 1557-9662",10.1109/TIM.2017.2754698,http://ieeexplore.ieee.org/document/8057841/,,2018-01,21/11/2018 11:48,14/04/2020 08:34,21/11/2018 11:48,90-100,,1,67,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WQR79FVM,conferencePaper,2010,"Sheng, Wang; Xin, Qian; Guangli, Lin",A study on highway network emergent resource scheduling in regional heavy snow and server rime disasters,2010 International Conference on Logistics Systems and Intelligent Management (ICLSIM),978-1-4244-7331-1,,10.1109/ICLSIM.2010.5461242,http://ieeexplore.ieee.org/document/5461242/,,2010-01,21/11/2018 11:48,14/04/2020 08:35,21/11/2018 11:48,1609-1612,,,,,,,,,,,IEEE,"Harbin, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2010 International Conference on Logistics Systems and Intelligent Management (ICLSIM),,,,,,,,,,,,,,, FK4YC7LK,conferencePaper,2013,"Swarup, Samarth; Lum, Kristian; Barrett, Christopher L.; Bisset, Keith; Eubank, Stephen G.; Marathe, Madhav V.; Stretz, Paula",A Synthetic Information Approach to Urban-Scale Disaster Modeling,2013 IEEE 16th International Conference on Computational Science and Engineering,978-0-7695-5096-1,,10.1109/CSE.2013.161,http://ieeexplore.ieee.org/document/6755342/,,2013-12,21/11/2018 11:48,14/04/2020 08:35,21/11/2018 11:48,1105-1112,,,,,,,,,,,IEEE,"Sydney, Australia",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2013 IEEE 16th International Conference on Computational Science and Engineering (CSE),,,,,,,,,,,,,,, 9XCVUSL6,journalArticle,2002,"Virone, G.; Noury, N.; Demongeot, J.",A system for automatic measurement of circadian activity deviations in telemedicine,IEEE Transactions on Biomedical Engineering,,0018-9294,10.1109/TBME.2002.805452,http://ieeexplore.ieee.org/document/1159139/,,2002-12,21/11/2018 11:48,14/04/2020 08:35,21/11/2018 11:48,1463-1469,,12,49,,,,,,,,,,en,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, C7TKS3V9,conferencePaper,2012,"Carnevale, C.; Finzi, G.; Pisoni, E.; Volta, M.",A system of systems for air quality decision making,2012 7th International Conference on System of Systems Engineering (SoSE),978-1-4673-2975-0 978-1-4673-2974-3 978-1-4673-2973-6,,10.1109/SYSoSE.2012.6384184,http://ieeexplore.ieee.org/document/6384184/,,2012-07,21/11/2018 11:48,14/04/2020 08:34,21/11/2018 11:48,258-263,,,,,,,,,,,IEEE,Genova,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 7th International Conference on System of Systems Engineering (SoSE),,,,,,,,,,,,,,, Z743QCUZ,conferencePaper,2010,"Groop, Johan; Reijonsaari, Karita; Lillrank, Paul",A Theory of Constraints Approach to Health Technology Assessment,"2010 Second International Conference on eHealth, Telemedicine, and Social Medicine",978-1-4244-5803-5,,10.1109/eTELEMED.2010.28,http://ieeexplore.ieee.org/document/5432846/,"Applying assessment methods commonly used in healthcare, such as randomized controlled trials (RCT) and financial analysis, often proves challenging in health technology assessment (HTA). Procurement and implementation of process improving information and communication technology (ICT) is traditionally sought to be based on financial estimates. These are often difficult to produce and may be misleading. There is a need for a more pragmatic managerial solution. This paper suggests an alternative approach, based on the theory of constraints (TOC), arguing that the primary focus of technology assessment should be on technologies' ability to break or alleviate organizational constraints, in order to increase throughput rather than reduce cost. Ultimately the latter will become as a consequence of the former. This paper presents a conceptual contribution. The suggested approach is illustrated through a case study of a home care unit.",2010-02,21/11/2018 11:48,14/04/2020 08:34,21/11/2018 11:48,147-152,,,,,,,,,,,IEEE,"St. Maarten, Netherlands Antilles",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2010 Second International Conference on eHealth, Telemedicine, and Social Medicine (ETELEMED)",,,,,,,,,,,,,,, XHS3FCAN,conferencePaper,2012,"Arvinti, Beatrice; Costache, Marius; Isar, Alexandru",A three step algorithm based on biorthogonal wavelets for an intelligent cardiac remote monitoring system,2012 IEEE 16th International Conference on Intelligent Engineering Systems (INES),978-1-4673-2695-7 978-1-4673-2694-0 978-1-4673-2693-3,,10.1109/INES.2012.6249895,http://ieeexplore.ieee.org/document/6249895/,,2012-06,21/11/2018 11:48,14/04/2020 08:34,21/11/2018 11:48,549-554,,,,,,,,,,,IEEE,"Lisbon, Portugal",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 IEEE 16th International Conference on Intelligent Engineering Systems (INES),,,,,,,,,,,,,,, 6C6885CA,conferencePaper,2014,"Shao, Liqun; Gao, Zhanbao",A useful technology for PHM with signal simulation,2014 Prognostics and System Health Management Conference (PHM-2014 Hunan),978-1-4799-7958-5 978-1-4799-7957-8,,10.1109/PHM.2014.6988197,http://ieeexplore.ieee.org/document/6988197/,,2014-08,21/11/2018 11:48,14/04/2020 08:35,21/11/2018 11:48,373-377,,,,,,,,,,,IEEE,"Zhangiiaijie City, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2014 Prognostics and System Health Management Conference (PHM-2014 Hunan),,,,,,,,,,,,,,, TE3ZUSM5,conferencePaper,2017,"Jankowski, Natalie; Schonijahn, Laura; Kreitlow, Adina; Gotze, Elsa; Wahl, Michael",A user-centered design approach in the development of rehabilitation devices after stroke,2017 International Conference on Rehabilitation Robotics (ICORR),978-1-5386-2296-4,,10.1109/ICORR.2017.8009374,https://ieeexplore.ieee.org/document/8009374/,,2017-07,21/11/2018 11:48,14/04/2020 08:34,21/11/2018 11:48,965-970,,,,,,,,,,,IEEE,London,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 International Conference on Rehabilitation Robotics (ICORR),,,,,,,,,,,,,,, 2JHRSYY7,conferencePaper,2013,"Paiva, Paulo Vinicius de Farias; Machado, Liliane S.; Valenca, Ana Maria Gondim",A Virtual Environment for Training and Assessment of Surgical Teams,2013 XV Symposium on Virtual and Augmented Reality,978-0-7695-5001-5,,10.1109/SVR.2013.22,http://ieeexplore.ieee.org/document/6655758/,,2013-05,21/11/2018 11:48,14/04/2020 08:35,21/11/2018 11:48,17-26,,,,,,,,,,,IEEE,"Cuiabá - Mato Grosso, Brazil",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2013 XV Symposium on Virtual and Augmented Reality (SVR),,,,,,,,,,,,,,, UJYEGPPL,conferencePaper,2017,"Mao, Kedun; Zhu, Yongxin; Chen, Zhixiong; Tao, Xiang; Xue, Qixuan; Wu, Han; Mao, Yishu; Hou, Junjie",A Visual Model-Based Evaluation Framework of Cloud-Based Prognostics and Health Management,2017 IEEE International Conference on Smart Cloud (SmartCloud),978-1-5386-3684-8,,10.1109/SmartCloud.2017.12,http://ieeexplore.ieee.org/document/8118415/,,2017-11,21/11/2018 11:48,14/04/2020 08:34,21/11/2018 11:48,33-40,,,,,,,,,,,IEEE,"New York, NY",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 IEEE International Conference on Smart Cloud (SmartCloud),,,,,,,,,,,,,,, UDPJBPXZ,conferencePaper,2009,"Giannoulis, S.; Prayati, A.; Antonopoulos, C.; Papadopoulos, G.",A.MO.R : An adaptive routing mechanism for WSN health applications,Proceedings of the 3d International ICST Conference on Pervasive Computing Technologies for Healthcare,,,10.4108/ICST.PERVASIVEHEALTH2009.5984,http://eudl.eu/doi/10.4108/ICST.PERVASIVEHEALTH2009.5984,,2009,21/11/2018 11:48,14/04/2020 08:34,21/11/2018 11:48,,,,,,,A.MO.R,,,,,ICST,"London, UK",en,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,3d International ICST Conference on Pervasive Computing Technologies for Healthcare,,,,,,,,,,,,,,, TMUW55I5,journalArticle,2011,"Khan, Zafar; Sohn, Won",Abnormal human activity recognition system based on R-transform and kernel discriminant technique for elderly home care,IEEE Transactions on Consumer Electronics,,0098-3063,10.1109/TCE.2011.6131162,http://ieeexplore.ieee.org/document/6131162/,,2011-11,21/11/2018 11:48,14/04/2020 08:34,21/11/2018 11:48,1843-1850,,4,57,,,,,,,,,,,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, AT7IBBSU,journalArticle,2015,"Ling, Man Ho; Tsui, Kwok Leung; Balakrishnan, Narayanaswamy",Accelerated Degradation Analysis for the Quality of a System Based on the Gamma Process,IEEE Transactions on Reliability,,"0018-9529, 1558-1721",10.1109/TR.2014.2337071,http://ieeexplore.ieee.org/document/6860326/,,2015-03,21/11/2018 11:48,14/04/2020 08:34,21/11/2018 11:48,463-472,,1,64,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, P7L6GWRZ,conferencePaper,2006,"Yu, Zhou; Thibault, Jean-Baptiste; Sauer, Ken; Bouman, Charles; Hsieh, Jiang",Accelerated Line Search for Coordinate Descent Optimization,2006 IEEE Nuclear Science Symposium Conference Record,978-1-4244-0560-2,,10.1109/NSSMIC.2006.356469,http://ieeexplore.ieee.org/document/4179626/,,2006,21/11/2018 11:48,14/04/2020 08:35,21/11/2018 11:48,2841-2844,,,,,,,,,,,IEEE,"San Diego, CA, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2006 IEEE Nuclear Science Symposium Conference Record,,,,,,,,,,,,,,, XH46HNWM,journalArticle,2013,"Donghwan Kim; Pal, Debashish; Thibault, Jean-Baptiste; Fessler, Jeffrey A.",Accelerating Ordered Subsets Image Reconstruction for X-ray CT Using Spatially Nonuniform Optimization Transfer,IEEE Transactions on Medical Imaging,,"0278-0062, 1558-254X",10.1109/TMI.2013.2266898,http://ieeexplore.ieee.org/document/6527279/,,2013-11,21/11/2018 11:48,14/04/2020 08:34,21/11/2018 11:48,1965-1978,,11,32,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, M95NZMHS,conferencePaper,2010,"Zhao, Sisi; Zhou, Chenghu",Accelerating spatial clustering detection of epidemic disease with graphics processing unit,2010 18th International Conference on Geoinformatics,978-1-4244-7301-4,,10.1109/GEOINFORMATICS.2010.5567882,http://ieeexplore.ieee.org/document/5567882/,,2010-06,21/11/2018 11:48,14/04/2020 08:35,21/11/2018 11:48,01-Jun,,,,,,,,,,,IEEE,"Beijing, China",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2010 18th International Conference on Geoinformatics,,,,,,,,,,,,,,, VQ7ZVFZK,conferencePaper,2011,"Wang, Di; Rundensteiner, Elke; Ellison, Richard T.; Wang, Han",Active Complex Event Processing infrastructure: Monitoring and reacting to event streams,2011 IEEE 27th International Conference on Data Engineering Workshops,978-1-4244-9195-7,,10.1109/ICDEW.2011.5767635,http://ieeexplore.ieee.org/document/5767635/,,2011-04,21/11/2018 11:48,14/04/2020 08:35,21/11/2018 11:48,249-254,,,,,,Active Complex Event Processing infrastructure,,,,,IEEE,"Hannover, Germany",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2011 IEEE International Conference on Data Engineering Workshops (ICDEW),,,,,,,,,,,,,,, WEDNBXWJ,conferencePaper,2015,"Garcia, Filipa; Ferreira, Joao P.; Ferreira, Paulo; Cruz, Stephane; Crisostomo, Manuel; Coimbra, A. Paulo",Active pedal exerciser for leg rehabilitation,2015 IEEE 4th Portuguese Meeting on Bioengineering (ENBENG),978-1-4799-8269-1,,10.1109/ENBENG.2015.7088802,http://ieeexplore.ieee.org/document/7088802/,,2015-02,21/11/2018 11:48,14/04/2020 08:34,21/11/2018 11:48,01-Jan,,,,,,,,,,,IEEE,"Porto, Portugal",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 IEEE 4th Portuguese Meeting on Bioengineering (ENBENG),,,,,,,,,,,,,,, YSV4JCBQ,conferencePaper,2015,"Sarni, Tomi; Pulli, Petri",Activity Support Framework for People with Dementia Based on Markov Decision Process,2015 International Conference on Intelligent Environments,978-1-4673-6654-0,,10.1109/IE.2015.12,http://ieeexplore.ieee.org/document/7194267/,"Ambient assisted living technologies (AALT) are considered to offer means for reducing health care burden to societies by prolonging capability for independent living and by improving the quality of life for elderly persons suffering from dementia and their caregivers. This research presents a novel activity support framework for transforming cooking activities in to workflow process models optimized for people suffering from dementia. This is achieved by first splitting a cooking activity in to tasks composed of set of basic actions. Due to nature of dementia, actions taken by a care recipient can be considered to be stochastic. This research presents a model of a care recipient suffering from dementia based on data from literature. The model contains probability distribution of possible outcomes mapped to available basic actions in a cooking activity. This allows the use of Markov decision process (MDP) to determine optimal sequence of actions to perform a cooking activity. The resulting process models can be used as set of instructions by a prompting system or as a process model for a belief monitor type of AALTs. The designed framework was tested by comparing manually constructed and verified process model to one produced by a test computer program. Further research is needed to refine the care recipient model, study transforming cooking recipes into cooking activity models and to validate the framework in real-world settings.",2015-07,21/11/2018 11:48,14/04/2020 08:35,21/11/2018 11:48,25-32,,,,,,,,,,,IEEE,"Prague, Czech Republic",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 International Conference on Intelligent Environments (IE),,,,,,,,,,,,,,, UHCK2MLA,conferencePaper,2006,"Jao, Chiang S.; Hier, Daniel B.",Adapting User Interface to Expedite Physician Order Entry: A Frontline to Ensure Patient Safety,"2006 IEEE International Conference on Systems, Man and Cybernetics",978-1-4244-0099-7 978-1-4244-0100-0,,10.1109/ICSMC.2006.384990,http://ieeexplore.ieee.org/document/4274125/,,2006-10,21/11/2018 11:48,14/04/2020 08:34,21/11/2018 11:48,1799-1803,,,,,,Adapting User Interface to Expedite Physician Order Entry,,,,,IEEE,"Taipei, Taiwan",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2006 IEEE International Conference on Systems, Man and Cybernetics",,,,,,,,,,,,,,, T3PAA47Q,conferencePaper,2015,"Antoniou, Z.; Panayides, A. S.; Pattichis, M. S.; Stavrou, S.; Kyriacou, E.; Spanias, A.; Constantinides, A. G.; Pattichis, C. 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Rahman, Roslan Abd; Ishak Raja, Raja; Tahmasebi, Mona",Bus seat suspension modification for pregnant women,2012 International Conference on Biomedical Engineering (ICoBE),978-1-4577-1991-2 978-1-4577-1990-5 978-1-4577-1989-9,,10.1109/ICoBE.2012.6179047,http://ieeexplore.ieee.org/document/6179047/,,2012-02,21/11/2018 11:49,14/04/2020 08:34,21/11/2018 11:49,404-407,,,,,,,,,,,IEEE,"Penang, Malaysia",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 International Conference on Biomedical Engineering (ICoBE),,,,,,,,,,,,,,, 2Q2NYIND,conferencePaper,2009,"Chan, T.H.T.; Shih, H.W.; Thambiratnam, D.P.",Case studies on vibration based damage identification: Multi-criteria approach,"2009 8th International Conference on Reliability, Maintainability and Safety",978-1-4244-4903-3 978-1-4244-4905-7,,10.1109/ICRMS.2009.5270044,http://ieeexplore.ieee.org/document/5270044/,,2009-07,21/11/2018 11:49,14/04/2020 08:34,21/11/2018 11:49,1242-1247,,,,,,Case studies on vibration based damage identification,,,,,IEEE,"Chengdu, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2009 8th International Conference on Reliability, Maintainability and Safety (ICRMS 2009)",,,,,,,,,,,,,,, GGN9NUVS,conferencePaper,2015,"Papadopoulos, George","Challenges in the design and implementation of wireless sensor networks: A holistic approach-development and planning tools, middleware, power efficiency, interoperability",2015 4th Mediterranean Conference on Embedded Computing (MECO),978-1-4799-8999-7 978-1-4799-1976-5,,10.1109/MECO.2015.7181857,http://ieeexplore.ieee.org/document/7181857/,,2015-06,21/11/2018 11:49,14/04/2020 08:35,21/11/2018 11:49,01-Mar,,,,,,Challenges in the design and implementation of wireless sensor networks,,,,,IEEE,Budva,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 4th Mediterranean Conference on Embedded Computing (MECO),,,,,,,,,,,,,,, M9MCUTPB,conferencePaper,2017,"Yoneda, Terumi; Itami, Kimiwa; Yasuhara, Osamu; Seki, Keiko; Kawabata, Yoshino; Maesako, Takanori; Zhe, Li",Changes in Subjective Understanding of an Accident and Risk Awareness in First-Year Nursing Students Following Medical Accident Simulation-Based Experimental Learning,2017 International Conference of Educational Innovation through Technology (EITT),978-1-5386-0629-2,,10.1109/EITT.2017.46,http://ieeexplore.ieee.org/document/8308531/,,2017-12,21/11/2018 11:49,14/04/2020 08:35,21/11/2018 11:49,159-164,,,,,,,,,,,IEEE,Osaka,,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 International Conference of Educational Innovation through Technology (EITT),,,,,,,,,,,,,,, 6RRTERCT,journalArticle,2018,"Devikanniga, D.; Joshua Samuel Raj, R.",Classification of osteoporosis by artificial neural network based on monarch butterfly optimisation algorithm,Healthcare Technology Letters,,2053-3713,10.1049/htl.2017.0059,http://digital-library.theiet.org/content/journals/10.1049/htl.2017.0059,,01/04/2018,21/11/2018 11:49,14/04/2020 08:34,21/11/2018 11:49,70-75,,2,5,,,,,,,,,,en,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DU6WBZ9A,conferencePaper,2016,"Davaslioglu, Kemal; Liu, Yang; Gitlin, Richard D.",CLOEE - Cross-Layer Optimization for Energy Efficiency of IEEE 802.15.6 IR-UWB WBANs,2016 IEEE Global Communications Conference (GLOBECOM),978-1-5090-1328-9,,10.1109/GLOCOM.2016.7841659,http://ieeexplore.ieee.org/document/7841659/,,2016-12,21/11/2018 11:49,14/04/2020 08:34,21/11/2018 11:49,01-Jul,,,,,,,,,,,IEEE,"Washington, DC, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GLOBECOM 2016 - 2016 IEEE Global Communications Conference,,,,,,,,,,,,,,, 2HTBSWGY,conferencePaper,2009,"Yu, Yue; Wang, Xiao-ling; Zhang, Zi-qiang; Li, Tao",CO Diffusion Simulation in the Third Layer Construction of Main Power House,2009 International Conference on Management and Service Science,978-1-4244-4638-4,,10.1109/ICMSS.2009.5303514,http://ieeexplore.ieee.org/document/5303514/,,2009-09,21/11/2018 11:49,14/04/2020 08:35,21/11/2018 11:49,01-Apr,,,,,,,,,,,IEEE,"Beijing, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2009 International Conference on Management and Service Science (MASS),,,,,,,,,,,,,,, NSK7G9WU,conferencePaper,2010,Hanlei Zhang; Mo-Yuen Chow,Comprehensive dynamic battery modeling for PHEV applications,IEEE PES General Meeting,978-1-4244-6549-1,,10.1109/PES.2010.5590108,http://ieeexplore.ieee.org/document/5590108/,,2010-07,21/11/2018 11:49,14/04/2020 08:34,21/11/2018 11:49,01-Jun,,,,,,,,,,,IEEE,"Minneapolis, MN",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Energy Society General Meeting,,,,,,,,,,,,,,, FAQRYYYG,conferencePaper,2010,"Zander, Justyna; Mosterman, Pieter J.; Kinnebrew, John S.; Biswas, Gautam",Computation of things for human protection and fulfillment,2010 IEEE International Conference on Technologies for Homeland Security (HST),978-1-4244-6047-2,,10.1109/THS.2010.5655070,http://ieeexplore.ieee.org/document/5655070/,,2010-11,21/11/2018 11:50,14/04/2020 08:35,21/11/2018 11:50,153-159,,,,,,,,,,,IEEE,"Waltham, MA, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2010 IEEE International Conference on Technologies for Homeland Security (HST),,,,,,,,,,,,,,, P8UP4EQL,journalArticle,2009,"Lai, D.T.H.; Begg, R.K.; Palaniswami, M.",Computational Intelligence in Gait Research: A Perspective on Current Applications and Future Challenges,IEEE Transactions on Information Technology in Biomedicine,,1089-7771,10.1109/TITB.2009.2022913,http://ieeexplore.ieee.org/document/4915787/,,2009-09,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,687-702,,5,13,,,Computational Intelligence in Gait Research,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HL3XR3GN,journalArticle,2015,"Alghassi, Alireza; Perinpanayagam, Suresh; Samie, Mohammad; Sreenuch, Tarapong","Computationally Efficient, Real-Time, and Embeddable Prognostic Techniques for Power Electronics",IEEE Transactions on Power Electronics,,"0885-8993, 1941-0107",10.1109/TPEL.2014.2360662,http://ieeexplore.ieee.org/document/6915717/,,2015-05,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,2623-2634,,5,30,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XQUCC3F2,conferencePaper,2010,"Grantner, Janos; Bazuin, Bradley; Liang Dong; Al-shawawreh, Jumana; Castanier, Matthew P.; Hussain, Shabbir",Condition Based Maintenance for light trucks,"2010 IEEE International Conference on Systems, Man and Cybernetics",978-1-4244-6586-6,,10.1109/ICSMC.2010.5641796,http://ieeexplore.ieee.org/document/5641796/,,2010-10,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,336-342,,,,,,,,,,,IEEE,"Istanbul, Turkey",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2010 IEEE International Conference on Systems, Man and Cybernetics - SMC",,,,,,,,,,,,,,, 9ZEEHYYH,conferencePaper,2008,"Gomez, Elizabeth Avery",Connecting Communities of Need with Public Health: Can SMS Text-Messaging Improve Outreach Communication?,Proceedings of the 41st Annual Hawaii International Conference on System Sciences (HICSS 2008),,,10.1109/HICSS.2008.99,http://ieeexplore.ieee.org/document/4438831/,"Communities of need face many health crises and often rely on our public health system or their community-based organizations for help in lieu of medical practitioners or clinics. These same communities also turn to affordable cell phones in lieu of landlines for mobility, and cost savings. Public health practitioners and community practitioners who provide local services find ongoing communication with these individuals in communities of need, can be a challenge and raises our research question. Can SMS text-messaging be used as an affordable means to improve outreach communication and disseminate information between community practitioners? Afield study of 50 participants was conducted to collect communication protocol responses through an SMS text-messaging simulation. The Web-based training application presented a crisis scenario and plain language training. The findings of this study suggest potential use of SMS text-messaging as a communication medium for exchange between field practitioners. A contribution of this research is the data collection in a community setting for analysis in bridging the digital divide where affordability is a limitation.",2008-01,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,128-128,,,,,,Connecting Communities of Need with Public Health,,,,,IEEE,"Waikoloa, HI, USA",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2008 The 41st Annual Hawaii International Conference on System Sciences,,,,,,,,,,,,,,, GWTQSCEW,conferencePaper,2010,"Li, Li; Hooman, Jozef; Voeten, Jeroen",Connecting Technical and Non-technical Views of System Architectures,"2010 IEEE/ACM Int'l Conference on Green Computing and Communications & Int'l Conference on Cyber, Physical and Social Computing",978-1-4244-9779-9,,10.1109/GreenCom-CPSCom.2010.123,http://ieeexplore.ieee.org/document/5724892/,,2010-12,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,592-599,,,,,,,,,,,IEEE,"Hangzhou, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Int'l Conference on Cyber, Physical and Social Computing (CPSCom)",,,,,,,,,,,,,,, UGEEX4R3,conferencePaper,2012,"Le, Quang-Tuan; Chan-Sik Park",Construction safety education model based on second life,"Proceedings of IEEE International Conference on Teaching, Assessment, and Learning for Engineering (TALE) 2012",978-1-4673-2418-2 978-1-4673-2417-5 978-1-4673-2416-8,,10.1109/TALE.2012.6360336,http://ieeexplore.ieee.org/document/6360336/,,2012-08,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,H2C-1-H2C-5,,,,,,,,,,,IEEE,"Hong Kong, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2012 IEEE International Conference on Teaching, Assessment and Learning for Engineering (TALE)",,,,,,,,,,,,,,, IGJKJTWY,conferencePaper,2015,"Jacob, Anil K; Kishore, Geethu S; Jacob, Lillykutty",Contention versus polling access in IEEE 802.15.6: Delay and lifetime analysis,2015 Twenty First National Conference on Communications (NCC),978-1-4799-6619-6,,10.1109/NCC.2015.7084902,http://ieeexplore.ieee.org/document/7084902/,,2015-02,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,01-Jun,,,,,,Contention versus polling access in IEEE 802.15.6,,,,,IEEE,"Mumbai, India",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 Twenty First National Conference on Communications (NCC),,,,,,,,,,,,,,, UWMBE2N3,conferencePaper,2009,"Pawar, Pravin; Beijnum, Bert-Jan van; Hermens, Hermie; Wac, Katarzyna; Konstantas, Dimitri",Context-Aware Computing Support for Network-Assisted Seamless Vertical Handover in Remote Patient Monitoring,2009 International Conference on Advanced Information Networking and Applications Workshops,978-1-4244-3999-7,,10.1109/WAINA.2009.191,http://ieeexplore.ieee.org/document/5136673/,,2009-05,21/11/2018 11:50,14/04/2020 08:35,21/11/2018 11:50,351-358,,,,,,,,,,,IEEE,"Bradford, United Kingdom",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2009 International Conference on Advanced Information Networking and Applications Workshops (WAINA),,,,,,,,,,,,,,, L2SGLXMC,conferencePaper,2014,"Costa, Javier Mendonca; Miao, Guowang",Context-aware Machine-to-Machine communications,2014 IEEE Conference on Computer Communications Workshops (INFOCOM WKSHPS),978-1-4799-3088-3,,10.1109/INFCOMW.2014.6849321,http://ieeexplore.ieee.org/document/6849321/,,2014-04,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,730-735,,,,,,,,,,,IEEE,"Toronto, ON, Canada",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEEE INFOCOM 2014 - IEEE Conference on Computer Communications Workshops (INFOCOM WKSHPS),,,,,,,,,,,,,,, 79685EKB,conferencePaper,2018,"Nieto-Chaupis, Huber",Continuous Surveillance By Tele-consults Based on Monte Carlo Algorithms to Anticipate and Lessen Risk Levels Due to Type-2 Diabetes Complications,2018 IEEE 1st Colombian Conference on Applications in Computational Intelligence (ColCACI),978-1-5386-6740-8,,10.1109/ColCACI.2018.8484853,https://ieeexplore.ieee.org/document/8484853/,,2018-05,21/11/2018 11:50,14/04/2020 08:35,21/11/2018 11:50,01-May,,,,,,,,,,,IEEE,Medellin,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2018 IEEE 1st Colombian Conference on Applications in Computational Intelligence (ColCACI),,,,,,,,,,,,,,, 5CUCB2DH,journalArticle,2005,"Sacks, H.K.; Novak, T.",Corona-Discharge-Initiated Mine Explosions,IEEE Transactions on Industry Applications,,0093-9994,10.1109/TIA.2005.853387,http://ieeexplore.ieee.org/document/1510829/,,2005-09,21/11/2018 11:50,14/04/2020 08:35,21/11/2018 11:50,1316-1322,,5,41,,,,,,,,,,en,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, U34N55AK,conferencePaper,2012,"Lall, Pradeep; Lowe, Ryan; Goebel, Kai; Cooper, Will",Cost assessment for implementation of embedded prognostic health management for electronic systems,13th InterSociety Conference on Thermal and Thermomechanical Phenomena in Electronic Systems,978-1-4244-9532-0 978-1-4244-9533-7 978-1-4244-9531-3,,10.1109/ITHERM.2012.6231471,http://ieeexplore.ieee.org/document/6231471/,,2012-05,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,487-497,,,,,,,,,,,IEEE,"San Diego, CA, USA",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 13th IEEE Intersociety Conference on Thermal and Thermomechanical Phenomena in Electronic Systems (ITherm),,,,,,,,,,,,,,, N3VE8DEI,conferencePaper,2005,"Rejeb, R.; Leeson, M.S.; Green, R.J.",Cost optimization method for multiple attack localization and identification in all-optical networks,"Proceedings of 2005 7th International Conference Transparent Optical Networks, 2005.",978-0-7803-9236-6,,10.1109/ICTON.2005.1505761,http://ieeexplore.ieee.org/document/1505761/,,2005,21/11/2018 11:50,14/04/2020 08:35,21/11/2018 11:50,101-106,,,1,,,,,,,,IEEE,"Barcelona, Catalonia, Spain",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2005 7th International Conference Transparent Optical Networks, 2005.",,,,,,,,,,,,,,, KWFPP5JF,conferencePaper,2013,"Wu, Bo; Jia, Xisheng; Xia, Lianghua; Lei, Congying; Wang, Yabin",Cost-benefit analysis of the application of prognostics and health management technology,"2013 International Conference on Quality, Reliability, Risk, Maintenance, and Safety Engineering (QR2MSE)",978-1-4799-1016-8 978-1-4799-1014-4,,10.1109/QR2MSE.2013.6625955,http://ieeexplore.ieee.org/document/6625955/,,2013-07,21/11/2018 11:50,14/04/2020 08:35,21/11/2018 11:50,1923-1927,,,,,,,,,,,IEEE,"Chengdu, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2013 International Conference on Quality, Reliability, Risk, Maintenance, and Safety Engineering (QR2MSE)",,,,,,,,,,,,,,, JBGZGS2X,journalArticle,2017,"Khazbak, Youssef; Izz, Mostafa; ElBatt, Tamer; Fahim, Abdulrahman; Guirguis, Arsany; Youssef, Moustafa",Cost-Effective Data Transfer for Mobile Health Care,IEEE Systems Journal,,"1932-8184, 1937-9234, 2373-7816",10.1109/JSYST.2016.2533419,http://ieeexplore.ieee.org/document/7441984/,,2017-12,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,2663-2674,,4,11,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NYTY77YM,conferencePaper,2012,"Ben Alla, Said; Ezzati, Abdellah",Coverage and Connectivity Preserving Routing Protocol for heterogeneous wireless sensor networks,2012 Next Generation Networks and Services (NGNS),978-1-4799-2167-6 978-1-4799-2168-3,,10.1109/NGNS.2012.6656097,http://ieeexplore.ieee.org/document/6656097/,,2012-12,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,141-148,,,,,,,,,,,IEEE,"Faro, Portugal",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 Next Generation Networks and Services (NGNS),,,,,,,,,,,,,,, XTDMQ7TV,conferencePaper,2005,"Parthasarathy, M.; Rapur, N.; Krishnan, P.",Criteria That Influence The Quality of Higher Education – A Student’s Perspective,2005 6th International Conference on Information Technology Based Higher Education and Training,978-0-7803-9141-3,,10.1109/ITHET.2005.1560292,http://ieeexplore.ieee.org/document/1560292/,,2005,21/11/2018 11:50,14/04/2020 08:35,21/11/2018 11:50,F3C-7-F3C-13,,,,,,,,,,,IEEE,"Santo Domingo, dominican Republic",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2005 6th International Conference on Information Technology Based Higher Education and Training,,,,,,,,,,,,,,, F97XFBDQ,conferencePaper,2009,"Kunst, Neil; Judkins, Justin; Lynn, Chris; Goodman, Doug",Damage propagation analysis methodology for electromechanical actuator prognostics,2009 IEEE Aerospace conference,978-1-4244-2621-8,,10.1109/AERO.2009.4839679,http://ieeexplore.ieee.org/document/4839679/,,2009-03,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,01-Jul,,,,,,,,,,,IEEE,"Big Sky, MT, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2009 IEEE Aerospace conference,,,,,,,,,,,,,,, EHAUW6YQ,journalArticle,2017,"Jiang, Yu; Song, Houbing; Wang, Rui; Gu, Ming; Sun, Jiaguang; Sha, Lui",Data-Centered Runtime Verification of Wireless Medical Cyber-Physical System,IEEE Transactions on Industrial Informatics,,"1551-3203, 1941-0050",10.1109/TII.2016.2573762,http://ieeexplore.ieee.org/document/7480373/,,2017-08,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,1900-1909,,4,13,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, T8S4276X,conferencePaper,2014,"Beykikhoshk, Adham; Arandjelovic, Ognjen; Phung, Dinh; Venkatesh, Svetha; Caelli, Terry",Data-mining twitter and the autism spectrum disorder: A Pilot study,2014 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining (ASONAM 2014),978-1-4799-5877-1,,10.1109/ASONAM.2014.6921609,http://ieeexplore.ieee.org/document/6921609/,,2014-08,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,349-356,,,,,,Data-mining twitter and the autism spectrum disorder,,,,,IEEE,China,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2014 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining (ASONAM),,,,,,,,,,,,,,, 52YMGY7X,conferencePaper,2018,"Ye, Dong Hye; Srivastava, Somesh; Thibault, Jean-Baptiste; Sauer, Ken; Bouman, Charles",Deep Residual Learning for Model-Based Iterative CT Reconstruction Using Plug-and-Play Framework,"2018 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP)",978-1-5386-4658-8,,10.1109/ICASSP.2018.8461408,https://ieeexplore.ieee.org/document/8461408/,,2018-04,21/11/2018 11:50,14/04/2020 08:35,21/11/2018 11:50,6668-6672,,,,,,,,,,,IEEE,"Calgary, AB",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"ICASSP 2018 - 2018 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP)",,,,,,,,,,,,,,, B2T5HSJE,conferencePaper,2010,"Bennebroek, Martijn; Barroso, Andre; Atallah, Louis; Lo, Benny; Yang, Guang-Zhong",Deployment of wireless sensors for remote elderly monitoring,"The 12th IEEE International Conference on e-Health Networking, Applications and Services",978-1-4244-6374-9,,10.1109/HEALTH.2010.5556586,http://ieeexplore.ieee.org/document/5556586/,,2010-07,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,01-May,,,,,,,,,,,IEEE,"Lyon, France",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2010 12th IEEE International Conference on e-Health Networking, Applications and Services (Healthcom 2010)",,,,,,,,,,,,,,, LDIEEFPI,conferencePaper,2013,"Brush, Zachary; Bowling, Alan; Tadros, Michael; Russell, Michael",Design and control of a smart bed for pressure ulcer prevention,2013 IEEE/ASME International Conference on Advanced Intelligent Mechatronics,978-1-4673-5320-5 978-1-4673-5319-9,,10.1109/AIM.2013.6584230,http://ieeexplore.ieee.org/document/6584230/,,2013-07,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,1033-1038,,,,,,,,,,,IEEE,"Wollongong, NSW",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2013 IEEE/ASME International Conference on Advanced Intelligent Mechatronics (AIM),,,,,,,,,,,,,,, 2U8CL5X5,conferencePaper,2011,"Kannoju, Praveen Kumar; Sridhar, K. V.; Prasad, K. S. R.",Design and Implementation of a Novel Approach to Implement Telemedicine in Rural India Using Advancements Made in Communications and Information Technology,"2011 Second International Conference on Intelligent Systems, Modelling and Simulation",978-1-4244-9809-3,,10.1109/ISMS.2011.31,http://ieeexplore.ieee.org/document/5730334/,"In India as per the survey conducted by Indian Medical Society (IMS) in the year 2009, it has been revealed that 75% of qualified consulting doctors practice in urban centers and 23% in semi urban areas and only 2% at rural areas whereas majority of the patients come from rural areas. The non availability of proper medical facilities at right time is a huge problem for people at rural places. Providing a cost-effective solution for this problem by utilizing the available resources to give good medical facilities to not only to urban but also to rural areas definitely reduces the gap present. The challenges that have to be faced to achieve this change are improve patient safety, improve the quality and efficiency of patient care, and reduce healthcare delivery costs at rural areas. The method that can be applied successfully to overcome all these challenges is Telemedicine. This paper introduces the innovative concept of developing an efficient Electronic Health Record (EHR) used to implement Telemedicine by utilizing the advances made in both Information technology and Communication systems. This application acts as a bridge between skilled doctors and the rural people.",2011-01,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,133-135,,,,,,,,,,,IEEE,"Phnom Penh, Cambodia",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2011 2nd International Conference on Intelligent Systems, Modelling and Simulation (ISMS)",,,,,,,,,,,,,,, RCPXKJ4R,conferencePaper,2015,"Gang-feng, Liu; Ying-yong, Zhang; Chang-le, Li; Ji-hong, Yan",Design and optimization of spraying robot arm for hull blocks,2015 IEEE International Conference on Robotics and Biomimetics (ROBIO),978-1-4673-9675-2,,10.1109/ROBIO.2015.7419734,http://ieeexplore.ieee.org/document/7419734/,,2015-12,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,2615-2620,,,,,,,,,,,IEEE,Zhuhai,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 IEEE International Conference on Robotics and Biomimetics (ROBIO),,,,,,,,,,,,,,, QIA6UAVJ,conferencePaper,2011,"Boudahri, Fethi; Sari, Zaki; Maliki, Fouad; Bennekrouf, Mohammed",Design and optimization of the supply chain of agri-foods: Application distribution network of chicken meat,"2011 International Conference on Communications, Computing and Control Applications (CCCA)",978-1-4244-9795-9,,10.1109/CCCA.2011.6031424,http://ieeexplore.ieee.org/document/6031424/,,2011-03,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,01-Jun,,,,,,Design and optimization of the supply chain of agri-foods,,,,,IEEE,"Hammamet, Tunisia",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2011 International Conference on Communications, Computing and Control Applications (CCCA)",,,,,,,,,,,,,,, EAT75TU2,conferencePaper,2017,"Putra, Renaldo Herdiano; Rahman, Ahmad Ghifari Wildan; Ningrum, Endah Suryawati; Purnomo, Didik Setyo",Design and stress analysis on electric standing wheelchair,2017 International Electronics Symposium on Engineering Technology and Applications (IES-ETA),978-1-5090-6772-5 978-1-5386-0712-1,,10.1109/ELECSYM.2017.8240388,http://ieeexplore.ieee.org/document/8240388/,,2017-09,21/11/2018 11:50,14/04/2020 08:35,21/11/2018 11:50,112-117,,,,,,,,,,,IEEE,Surabaya,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 International Electronics Symposium on Engineering Technology and Applications (IES-ETA),,,,,,,,,,,,,,, XJSQZ52K,conferencePaper,2013,Hongqiao Gao; Xiaohui Duan; Xiaoqiang Guo; Anpeng Huang; Bingli Jiao,Design and tests of a smartphones-based multi-lead ECG monitoring system,2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC),978-1-4577-0216-7,,10.1109/EMBC.2013.6609989,http://ieeexplore.ieee.org/document/6609989/,,2013-07,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,2267-2270,,,,,,,,,,,IEEE,Osaka,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC),,,,,,,,,,,,,,, G8QYRLAI,conferencePaper,2014,"Govind, K. R. Achu; Sekhar, R. Aravind",Design of a novel PID controller for cardiac pacemaker,2014 International Conference on Advances in Green Energy (ICAGE),978-1-4799-8050-5,,10.1109/ICAGE.2014.7050147,http://ieeexplore.ieee.org/document/7050147/,,2014-12,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,82-87,,,,,,,,,,,IEEE,"Thiruvananthapuram, India",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2014 International Conference on Advances in Green Energy (ICAGE),,,,,,,,,,,,,,, 9SSJP5QX,conferencePaper,2014,"Guo, Jing; Singer, Nicolas; Bastide, Rémi",Design of a serious game in training non-clinical skills for professionals in health care area,2014 IEEE 3nd International Conference on Serious Games and Applications for Health (SeGAH),978-1-4799-4823-9,,10.1109/SeGAH.2014.7067096,http://ieeexplore.ieee.org/document/7067096/,,2014-05,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,01-Jun,,,,,,,,,,,IEEE,"Rio de Janeiro, Brazil",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2014 IEEE 3rd International Conference on Serious Games and Applications for Health (SeGAH),,,,,,,,,,,,,,, 93HKM5G4,conferencePaper,2013,"Sunghwa Son; Park, Kyung-Joon; Eun-Chan Park",Design of adaptive IEEE 802.11 WLAN in hospital environments,"2013 IEEE 15th International Conference on e-Health Networking, Applications and Services (Healthcom 2013)",978-1-4673-5801-9 978-1-4673-5800-2,,10.1109/HealthCom.2013.6720771,http://ieeexplore.ieee.org/document/6720771/,,2013-10,21/11/2018 11:50,14/04/2020 08:35,21/11/2018 11:50,722-724,,,,,,,,,,,IEEE,"Lisbon, Portugal",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2013 IEEE 15th International Conference on e-Health Networking, Applications and Services (Healthcom 2013)",,,,,,,,,,,,,,, KI7RQZRD,conferencePaper,2018,"Hale, William T.; Palmer, Kyle A.; Stuber, Matthew D.; Bollas, George M.",Design of Built-In Tests for Robust Active Fault Detection and Isolation of Discrete Faults in Uncertain Systems,2018 Annual American Control Conference (ACC),978-1-5386-5428-6,,10.23919/ACC.2018.8431233,https://ieeexplore.ieee.org/document/8431233/,,2018-06,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,4989-4994,,,,,,,,,,,IEEE,"Milwaukee, WI",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2018 Annual American Control Conference (ACC),,,,,,,,,,,,,,, X5DNGIVW,conferencePaper,2015,"Albloushi, Tamador; Suwaidi, Aisha; Zarouni, Noura; Abdelrahman, Asma; Shamsuzzaman, Mohammad",Design of X̅&R control charts for monitoring quality of care for hypertension,2015 International Conference on Industrial Engineering and Operations Management (IEOM),978-1-4799-6065-1,,10.1109/IEOM.2015.7093914,http://ieeexplore.ieee.org/document/7093914/,,2015-03,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,01-May,,,,,,,,,,,IEEE,Dubai,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 International Conference on Industrial Engineering and Operations Management (IEOM),,,,,,,,,,,,,,, XF29PZGU,journalArticle,2014,"Singh, Lalit Kumar; Vinod, Gopika; Tripathi, A. K.",Design Verification of Instrumentation and Control Systems of Nuclear Power Plants,IEEE Transactions on Nuclear Science,,"0018-9499, 1558-1578",10.1109/TNS.2014.2305656,http://ieeexplore.ieee.org/document/6776553/,,2014-04,21/11/2018 11:50,14/04/2020 08:35,21/11/2018 11:50,921-930,,2,61,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CAXZ8X8X,conferencePaper,2012,"Font, Juan Luis; Sevillano, Jose Luis; Cascado-Caballero, Daniel; Lopez-Munoz, Gema; Regassa, Berhanu","Design, implementation and validation of a simulation tool for Networked Virtual Environments","2012 International Conference on Computer, Information and Telecommunication Systems (CITS)",978-1-4673-1550-0 978-1-4673-1549-4 978-1-4673-1548-7,,10.1109/CITS.2012.6220390,http://ieeexplore.ieee.org/document/6220390/,,2012-05,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,01-May,,,,,,,,,,,IEEE,"Amman, Jordan",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2012 International Conference on Computer, Information and Telecommunication Systems (CITS)",,,,,,,,,,,,,,, YBAI5FXR,conferencePaper,2008,"De Micheli, Giovanni",Designing micro/nano systems for a safer and healthier tomorrow,2008 International Conference on Signals and Electronic Systems,978-83-88309-47-2,,10.1109/ICSES.2008.4673337,http://ieeexplore.ieee.org/lpdocs/epic03/wrapper.htm?arnumber=4673337,,2008,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,03-Mar,,,,,,,,,,,IEEE,"Krakow, Poland",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2008 International Conference on Signals and Electronic Systems,,,,,,,,,,,,,,, ZH4J4TQB,conferencePaper,2015,"Tsakalakis, Michail; Bourbakis, Nikolaos G.","Designing of a low-cost, volumetric multi — Transducer phased array ultrasound system",2015 IEEE 15th International Conference on Bioinformatics and Bioengineering (BIBE),978-1-4673-7983-0,,10.1109/BIBE.2015.7367624,http://ieeexplore.ieee.org/document/7367624/,,2015-11,21/11/2018 11:50,14/04/2020 08:35,21/11/2018 11:50,01-Jul,,,,,,,,,,,IEEE,"Belgrade, Serbia",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 IEEE 15th International Conference on Bioinformatics and Bioengineering (BIBE),,,,,,,,,,,,,,, RERM9SUT,journalArticle,2018,"Deng, Xianjun; Yang, Laurence T.; Yi, Lingzhi; Wang, Minghua; Zhu, Zhiliang",Detecting Confident Information Coverage Holes in Industrial Internet of Things: An Energy-Efficient Perspective,IEEE Communications Magazine,,"0163-6804, 1558-1896",10.1109/MCOM.2018.1701195,https://ieeexplore.ieee.org/document/8466358/,,2018-09,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,68-73,,9,56,,,Detecting Confident Information Coverage Holes in Industrial Internet of Things,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CURBVRH8,conferencePaper,2013,"Qing Zhang; Karunanithi, Mohan; Rana, Rajib; Jiajun Liu",Determination of Activities of Daily Living of independent living older people using environmentally placed sensors,2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC),978-1-4577-0216-7,,10.1109/EMBC.2013.6611180,http://ieeexplore.ieee.org/document/6611180/,,2013-07,21/11/2018 11:50,14/04/2020 08:35,21/11/2018 11:50,7044-7047,,,,,,,,,,,IEEE,Osaka,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC),,,,,,,,,,,,,,, 53FFMFGG,conferencePaper,2010,"Owusu-Banahene, W.; Nti, I.K.; Sallis, P.J.",Developing a Geo-spatial Information Framework to Facilitate National Identification System (NIS) in Ghana,2010 Fourth UKSim European Symposium on Computer Modeling and Simulation,978-1-4244-9313-5,,10.1109/EMS.2010.112,http://ieeexplore.ieee.org/document/5703660/,,2010-11,21/11/2018 11:50,14/04/2020 08:35,21/11/2018 11:50,68-74,,,,,,,,,,,IEEE,"Pisa, Italy",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2010 European Modelling Symposium (EMS),,,,,,,,,,,,,,, RTVMM28C,conferencePaper,2012,"Desai, Savitha S.; Sangam, Vijendra S.; Joshi, Laxmi; Smita, K; Namazi, Asma; Swetha, G",Development and formulation of effective microbial (EM) technology for dairy industrial effluent treatment,2012 IEEE International Conference on Engineering Education: Innovative Practices and Future Trends (AICERA),978-1-4673-2269-0 978-1-4673-2267-6 978-1-4673-2268-3,,10.1109/AICERA.2012.6306702,http://ieeexplore.ieee.org/document/6306702/,,2012-07,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,01-Jun,,,,,,,,,,,IEEE,"Kottayam, India",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 IEEE International Conference on Engineering Education: Innovative Practices and Future Trends (AICERA),,,,,,,,,,,,,,, W587KX23,conferencePaper,2013,"Fujita, K.; Fujimoto, T.",Development of a Mobile Application Advertisement System That Lead a Health Care Function and the Advertisement,"2013 4th International Conference on Intelligent Systems, Modelling and Simulation",978-1-4673-5653-4 978-0-7695-4963-7,,10.1109/ISMS.2013.86,http://ieeexplore.ieee.org/document/6498333/,,2013-01,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,557-562,,,,,,,,,,,IEEE,Bangkok,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2013 Fourth International Conference on Intelligent Systems, Modelling and Simulation (ISMS 2013)",,,,,,,,,,,,,,, LM5C2MIU,conferencePaper,2018,"Ioller, Benjamin; Miki, Norihisa",Development of an automatic urine monitoring device using cross-selectivity sensing principle,2018 International Conference on Electronics Packaging and iMAPS All Asia Conference (ICEP-IAAC),978-4-9902188-5-0,,10.23919/ICEP.2018.8374315,https://ieeexplore.ieee.org/document/8374315/,,2018-04,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,324-327,,,,,,,,,,,IEEE,"Mie, Japan",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2018 International Conference on Electronics Packaging and iMAPS All Asia Conference (ICEP-IAAC),,,,,,,,,,,,,,, 7XGD4GFX,conferencePaper,2010,"Lai, M. H.; Nieh, H. M.; Teng, T. P.; Chen, J. J.; Huang, Y. Y.; Lu, Y. C.",Development of an hemodialysis simulator for interdisciplinary learning,2010 IEEE International Conference on Industrial Engineering and Engineering Management,978-1-4244-8501-7,,10.1109/IEEM.2010.5674325,http://ieeexplore.ieee.org/document/5674325/,,2010-12,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,2493-2497,,,,,,,,,,,IEEE,"Macao, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,EM),,,,,,,,,,,,,,, HBEHNLDS,conferencePaper,2008,"Gunal, M.M.; Pidd, M.",DGHPSim: Supporting smart thinking to improve hospital performance,2008 Winter Simulation Conference,978-1-4244-2707-9,,10.1109/WSC.2008.4736228,http://ieeexplore.ieee.org/document/4736228/,,2008-12,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,1484-1489,,,,,,DGHPSim,,,,,IEEE,"Miami, FL, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2008 Winter Simulation Conference (WSC),,,,,,,,,,,,,,, D6IK5ES3,conferencePaper,2014,"Zhao, Weili; Hou, Chenguang; Wang, Qihua",Diagnosis of aircraft engine performance deterioration based on support vector machines,"2014 10th International Conference on Reliability, Maintainability and Safety (ICRMS)",978-1-4799-6632-5,,10.1109/ICRMS.2014.7107133,http://ieeexplore.ieee.org/document/7107133/,,2014-08,21/11/2018 11:50,14/04/2020 08:35,21/11/2018 11:50,44-48,,,,,,,,,,,IEEE,"Guangzhou, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2014 International Conference on Reliability, Maintainability and Safety (ICRMS)",,,,,,,,,,,,,,, ATG84HFT,conferencePaper,2017,"Rajeswari, S.; Josephine, M.S.; Jeyabalaraja, V.",Dimension reduction: A PSO-PCNN optimization approach for attribute selection in high-dimensional medical database,"2017 IEEE International Conference on Power, Control, Signals and Instrumentation Engineering (ICPCSI)",978-1-5386-0813-5 978-1-5386-0814-2,,10.1109/ICPCSI.2017.8392128,https://ieeexplore.ieee.org/document/8392128/,,2017-09,21/11/2018 11:50,14/04/2020 08:35,21/11/2018 11:50,2306-2309,,,,,,Dimension reduction,,,,,IEEE,Chennai,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2017 IEEE International Conference on Power, Control, Signals and Instrumentation Engineering (ICPCSI)",,,,,,,,,,,,,,, UR288DUU,conferencePaper,2017,"Ramachandran, Vignesh Raja Karuppiah; Le, Duc V.; Meratnia, Nirvana; Havinga, Paul J. M","DiNAMAC: A disruption tolerant, reinforcement learning-based Mac protocol for implantable body sensor networks","2017 IEEE SmartWorld, Ubiquitous Intelligence & Computing, Advanced & Trusted Computed, Scalable Computing & Communications, Cloud & Big Data Computing, Internet of People and Smart City Innovation (SmartWorld/SCALCOM/UIC/ATC/CBDCom/IOP/SCI)",978-1-5386-0435-9,,10.1109/UIC-ATC.2017.8397664,https://ieeexplore.ieee.org/document/8397664/,,2017-08,21/11/2018 11:50,14/04/2020 08:35,21/11/2018 11:50,01-Sep,,,,,,DiNAMAC,,,,,IEEE,"San Francisco, CA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2017 IEEE SmartWorld, Ubiquitous Intelligence & Computing, Advanced & Trusted Computed, Scalable Computing & Communications, Cloud & Big Data Computing, Internet of People and Smart City Innovation (SmartWorld/SCALCOM/UIC/ATC/CBDCom/IOP/SCI)",,,,,,,,,,,,,,, TBDYR8D5,conferencePaper,2013,"Bera, Manas Kr.; Priya, P. S. Lal; Bandyopadhyay, B.; Paul, A. K.",Discrete-time sliding mode control of GMAW systems using infrequent output measurements,2013 European Control Conference (ECC),978-3-033-03962-9,,10.23919/ECC.2013.6669581,https://ieeexplore.ieee.org/document/6669581/,,2013-07,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,3736-3741,,,,,,,,,,,IEEE,Zurich,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2013 European Control Conference (ECC),,,,,,,,,,,,,,, 57NGE2YX,journalArticle,2018,"Castellana, Antonella; Carullo, Alessio; Corbellini, Simone; Astolfi, Arianna",Discriminating Pathological Voice From Healthy Voice Using Cepstral Peak Prominence Smoothed Distribution in Sustained Vowel,IEEE Transactions on Instrumentation and Measurement,,"0018-9456, 1557-9662",10.1109/TIM.2017.2781958,http://ieeexplore.ieee.org/document/8252713/,,2018-03,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,646-654,,3,67,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IBY2I3VR,journalArticle,2017,"Ma, Meng; Sun, Chuang; Chen, Xuefeng",Discriminative Deep Belief Networks with Ant Colony Optimization for Health Status Assessment of Machine,IEEE Transactions on Instrumentation and Measurement,,"0018-9456, 1557-9662",10.1109/TIM.2017.2735661,http://ieeexplore.ieee.org/document/8012551/,,2017-12,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,3115-3125,,12,66,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IDH4H5BJ,conferencePaper,2010,Xiaofeng Xu; Chong Tan; Jian Chen,Distortion optimization based on power allocation for wireless video sensors,"IET 3rd International Conference on Wireless, Mobile and Multimedia Networks (ICWMMN 2010)",978-1-84919-240-8,,10.1049/cp.2010.0607,http://digital-library.theiet.org/content/conferences/10.1049/cp.2010.0607,,2010,21/11/2018 11:50,14/04/2020 08:35,21/11/2018 11:50,17-20,,,,,,,,,,,IET,"Beijing, China",en,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"IET 3rd International Conference on Wireless, Mobile and Multimedia Networks (ICWMMN 2010)",,,,,,,,,,,,,,, VTT3ERT4,conferencePaper,2017,"Odesile, Adedayo; Thamilarasu, Geethapriya",Distributed intrusion detection using mobile agents in wireless body area networks,2017 Seventh International Conference on Emerging Security Technologies (EST),978-1-5386-4018-0,,10.1109/EST.2017.8090414,http://ieeexplore.ieee.org/document/8090414/,,2017-09,21/11/2018 11:50,14/04/2020 08:35,21/11/2018 11:50,144-149,,,,,,,,,,,IEEE,"Canterbury, United Kingdom",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 Seventh International Conference on Emerging Security Technologies (EST),,,,,,,,,,,,,,, TM7EMKSJ,journalArticle,2015,"Liu, Xuefeng; Cao, Jiannong; Song, Wen-Zhan; Guo, Peng; He, Zongjian",Distributed Sensing for High-Quality Structural Health Monitoring Using WSNs,IEEE Transactions on Parallel and Distributed Systems,,1045-9219,10.1109/TPDS.2014.2312911,http://ieeexplore.ieee.org/document/6776483/,,2015-03,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,738-747,,3,26,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ZA6YQYLJ,conferencePaper,2005,"Bardina, J.E.; Thirumalainambi, R.",Distributed Web-based Expert System for Launch Operations,"Proceedings of the Winter Simulation Conference, 2005.",978-0-7803-9519-0,,10.1109/WSC.2005.1574389,http://ieeexplore.ieee.org/document/1574389/,,2005,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,1291-1297,,,,,,,,,,,IEEE,"Orlando, FL. USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Winter Simulation Conference, 2005.",,,,,,,,,,,,,,, AFNT6DH3,conferencePaper,2007,"Ji, Yanqing; Ying, Hao; Farber, Margo S.; Yen, John; Dews, Peter; Miller, Richard E.; Massanari, R. Michael","Distributed, Collaborative Intelligent Agents for Proactive Post-Marketing Drug Safety Surveillance",NAFIPS 2007 - 2007 Annual Meeting of the North American Fuzzy Information Processing Society,978-1-4244-1213-6 978-1-4244-1214-3,,10.1109/NAFIPS.2007.383829,http://ieeexplore.ieee.org/document/4271052/,"Healthcare systems and insurers nationwide regularly make decisions regarding which drugs to include or exclude from their formularies based on evidence concerning benefits, risks, and costs of the medications. A major barrier to effective drug selection is the lack of sufficient published information on the safety of drugs, particularly new drugs. In this paper, we propose an innovative multi-agent system, named ADRMonitor, for actively monitoring and detecting signal pairs implicating anticipated or potential adverse drug reactions (ADRs) of interest at a healthcare facility. Each intelligent agent is empowered by a fuzzy logic-based computational recognition-primed decision (RPD) model where fuzzy logic is utilized to represent, interpret, and compute vague and/or subjective information. We conducted a simulation study based on thousands of hypothetical patient cases that were created on the basis of real patients who were prescribed the drug Cisapride in a local hospital. At the current stage, our focus is to establish that the system can outperform the spontaneous reporting approach in identifying signal pairs. Under certain conditions (e.g., without agent collaboration), our simulation results show that (1) ADRMonitor detected 21 out of 27 (78%) ADRs when the optimized RPD model was used as a gold standard; (2) the number of ADRs detected by the agents is (many) more than those detected by the spontaneous reporting strategy (assuming 10% reporting rate - high end of rates reported in the literature) at any particular time. The second result implies that useful information could be collected more timely by the proposed agent system for formulary decisions.",2007-06,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,158-163,,,,,,,,,,,IEEE,"San Diego, CA, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NAFIPS 2007 - 2007 Annual Meeting of the North American Fuzzy Information Processing Society,,,,,,,,,,,,,,, ZPSTMZRB,conferencePaper,2016,"Iwata, Haruko; Tsumoto, Shusaku; Hirano, Shoji",Dual Clustering for Clinical Care Construction,2016 IEEE International Conference on Healthcare Informatics (ICHI),978-1-5090-6117-4,,10.1109/ICHI.2016.56,http://ieeexplore.ieee.org/document/7776372/,,2016-10,21/11/2018 11:50,14/04/2020 08:34,21/11/2018 11:50,314-314,,,,,,,,,,,IEEE,"Chicago, IL, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 IEEE International Conference on Healthcare Informatics (ICHI),,,,,,,,,,,,,,, PY4DAN4N,conferencePaper,2007,"Xiuying Wang; Feng, David D.",Dual-scale medical image registration based on steerable wavelet,2007 IEEE Nuclear Science Symposium Conference Record,978-1-4244-0922-8,,10.1109/NSSMIC.2007.4436858,http://ieeexplore.ieee.org/document/4436858/,,2007,21/11/2018 11:51,14/04/2020 08:35,21/11/2018 11:51,3390-3394,,,,,,,,,,,IEEE,"Honolulu, HI, USA",,,,,,Crossref,,,,,,00; 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100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 International Conference on Open Source Systems & Technologies (ICOSST),,,,,,,,,,,,,,, 6PFQS6VS,conferencePaper,2006,"Tan, Yow-Yiong Edwin; Philip, Nada; Istepanian, Robert S. 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Annual International Conference of the IEEE Engineering in Medicine and Biology Society,,,,,,,,,,,,,,, W57TBW59,conferencePaper,2017,"Winchester, Woodrow W.; Washington, Valerie",Fulfilling the potential of consumer connected fitness technologies: Towards framing systems engineering involvement in user experience design,2017 Annual IEEE International Systems Conference (SysCon),978-1-5090-4623-2,,10.1109/SYSCON.2017.7934768,http://ieeexplore.ieee.org/document/7934768/,,2017-04,21/11/2018 11:52,14/04/2020 08:35,21/11/2018 11:52,01-Mar,,,,,,Fulfilling the potential of consumer connected fitness technologies,,,,,IEEE,"Montreal, QC, Canada",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 Annual IEEE International Systems Conference (SysCon),,,,,,,,,,,,,,, LBB5LFUJ,conferencePaper,2009,"Feng, Zhipeng; Zuo, Ming J.; Hao, Rujiang; Chu, Fulei",Gear crack assessment based on cyclic correlation analysis,"2009 8th International Conference on Reliability, Maintainability and Safety",978-1-4244-4903-3 978-1-4244-4905-7,,10.1109/ICRMS.2009.5269999,http://ieeexplore.ieee.org/document/5269999/,,2009-07,21/11/2018 11:52,14/04/2020 08:34,21/11/2018 11:52,1071-1076,,,,,,,,,,,IEEE,"Chengdu, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2009 8th International Conference on Reliability, Maintainability and Safety (ICRMS 2009)",,,,,,,,,,,,,,, UWF8WZ4L,conferencePaper,2014,"Holvenstot, Peter; Prieto, Diana; de Doncker, Elise",GPGPU parallelization of self-calibrating agent-based influenza outbreak simulation,2014 IEEE High Performance Extreme Computing Conference (HPEC),978-1-4799-6233-4 978-1-4799-6232-7,,10.1109/HPEC.2014.7041000,http://ieeexplore.ieee.org/document/7041000/,,2014-09,21/11/2018 11:52,14/04/2020 08:34,21/11/2018 11:52,01-Jun,,,,,,,,,,,IEEE,"Waltham, MA, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2014 IEEE High Performance Extreme Computing Conference (HPEC),,,,,,,,,,,,,,, GUJWV4MW,conferencePaper,2009,"Guo, Diansheng",Greedy Optimization for Contiguity-Constrained Hierarchical Clustering,2009 IEEE International Conference on Data Mining Workshops,978-1-4244-5384-9,,10.1109/ICDMW.2009.75,http://ieeexplore.ieee.org/document/5360479/,,2009-12,21/11/2018 11:52,14/04/2020 08:34,21/11/2018 11:52,591-596,,,,,,,,,,,IEEE,"Miami, FL, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2009 IEEE International Conference on Data Mining Workshops (ICDMW),,,,,,,,,,,,,,, L4DY3L2Z,conferencePaper,2011,"Vazquez-Vazquez, M.; Santana-Lopez, V.; Skodova, M.; Ferrero-Alvarez-Rementeria, J.; Torres-Olivera, A.",Hand hygiene training through a serious game: New ways of improving Safe Practices,2011 IEEE 1st International Conference on Serious Games and Applications for Health (SeGAH),978-1-4673-0434-4 978-1-4673-0433-7 978-1-4673-0432-0,,10.1109/SeGAH.2011.6165439,http://ieeexplore.ieee.org/document/6165439/,,2011-11,21/11/2018 11:52,14/04/2020 08:35,21/11/2018 11:52,01-Feb,,,,,,Hand hygiene training through a serious game,,,,,IEEE,"Braga, Portugal",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2011 IEEE 1st International Conference on Serious Games and Applications for Health (SeGAH),,,,,,,,,,,,,,, WH69DWRI,conferencePaper,2016,"Fortuna, Chris; Giraud-Carrier, Christophe; West, Joshua",Hand-to-Mouth Motion Tracking in Free-Living Conditions for Improved Weight Control,2016 IEEE International Conference on Healthcare Informatics (ICHI),978-1-5090-6117-4,,10.1109/ICHI.2016.62,http://ieeexplore.ieee.org/document/7776381/,,2016-10,21/11/2018 11:52,14/04/2020 08:34,21/11/2018 11:52,341-348,,,,,,,,,,,IEEE,"Chicago, IL, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 IEEE International Conference on Healthcare Informatics (ICHI),,,,,,,,,,,,,,, 5BRJASIH,journalArticle,2018,"Zhao, Ming; Lin, Jing",Health Assessment of Rotating Machinery Using a Rotary Encoder,IEEE Transactions on Industrial Electronics,,"0278-0046, 1557-9948",10.1109/TIE.2017.2739689,http://ieeexplore.ieee.org/document/8010369/,,2018-03,21/11/2018 11:52,14/04/2020 08:35,21/11/2018 11:52,2548-2556,,3,65,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3I4IPM93,conferencePaper,2006,"Camci, F.; Chinnam, R.B.",Hierarchical HMMs for Autonomous Diagnostics and Prognostics,The 2006 IEEE International Joint Conference on Neural Network Proceedings,978-0-7803-9490-2,,10.1109/IJCNN.2006.247092,http://ieeexplore.ieee.org/document/1716422/,,2006,21/11/2018 11:52,14/04/2020 08:34,21/11/2018 11:52,2445-2452,,,,,,,,,,,IEEE,"Vancouver, BC, Canada",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,The 2006 IEEE International Joint Conference on Neural Network Proceedings,,,,,,,,,,,,,,, YZFLFTFT,conferencePaper,2005,Sukhyun Lim; Byeong-Seok Shin,Hierarchical min-max octree applying adaptive blocks,"Proceedings of 7th International Workshop on Enterprise networking and Computing in Healthcare Industry, 2005. HEALTHCOM 2005.",978-0-7803-8940-3,,10.1109/HEALTH.2005.1500449,http://ieeexplore.ieee.org/document/1500449/,,2005,21/11/2018 11:52,14/04/2020 08:35,21/11/2018 11:52,238-242,,,,,,,,,,,IEEE,"Busan, South Korea",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,7th International Workshop on Enterprise Networking and Computing in Healthcare Industry. HEALTHCOM 2005,,,,,,,,,,,,,,, KMJU53P9,conferencePaper,2013,"Balouchestani, Mohammadreza; Raahemifar, Kaamran; Krishnan, Sridhar",High - Resolution QRS detection algorithm for wireless ECG systems based on compressed sensing theory,2013 IEEE 56th International Midwest Symposium on Circuits and Systems (MWSCAS),978-1-4799-0066-4,,10.1109/MWSCAS.2013.6674900,http://ieeexplore.ieee.org/document/6674900/,,2013-08,21/11/2018 11:52,14/04/2020 08:34,21/11/2018 11:52,1326-1329,,,,,,,,,,,IEEE,"Columbus, OH, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2013 IEEE 56th International Midwest Symposium on Circuits and Systems (MWSCAS),,,,,,,,,,,,,,, ZT7FVNL9,conferencePaper,2018,"Zheng, Gao; Wang, Chih-Yu; Friderikos, Vasilis; Dohler, Mischa",High Mobility Multi Modal E-Health Services,2018 IEEE International Conference on Communications (ICC),978-1-5386-3180-5,,10.1109/ICC.2018.8422887,https://ieeexplore.ieee.org/document/8422887/,,2018-05,21/11/2018 11:52,14/04/2020 08:35,21/11/2018 11:52,01-Jul,,,,,,,,,,,IEEE,"Kansas City, MO",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2018 IEEE International Conference on Communications (ICC 2018),,,,,,,,,,,,,,, KGXPT92H,conferencePaper,2012,"Akçetin, Perihan Isinsu; Ergen, Sinem Coleri; Sezgin, Tevfik Metin",HMM based inertial sensor system for coaching of rowing activity,2012 20th Signal Processing and Communications Applications Conference (SIU),978-1-4673-0056-8 978-1-4673-0055-1 978-1-4673-0053-7 978-1-4673-0054-4,,10.1109/SIU.2012.6204805,http://ieeexplore.ieee.org/document/6204805/,,2012-04,21/11/2018 11:52,14/04/2020 08:34,21/11/2018 11:52,01-Apr,,,,,,,,,,,IEEE,"Mugla, Turkey",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 20th Signal Processing and Communications Applications Conference (SIU),,,,,,,,,,,,,,, P39S57SB,conferencePaper,2018,"Makonese, T.; Meyer, J.",Household energisation in rural South Africa: A systems approach towards energy access,2018 International Conference on the Domestic Use of Energy (DUE),978-0-9946759-4-1,,10.23919/DUE.2018.8384410,https://ieeexplore.ieee.org/document/8384410/,,2018-04,21/11/2018 11:52,14/04/2020 08:34,21/11/2018 11:52,01-Jul,,,,,,Household energisation in rural South Africa,,,,,IEEE,Cape Town,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2018 International Conference on the Domestic Use of Energy (DUE),,,,,,,,,,,,,,, NQQTVK82,conferencePaper,2017,"Vetale, Sonal; Vidhate, A. V.",Hybrid data-centric routing protocol of wireless body area network,"2017 International Conference on Advances in Computing, Communication and Control (ICAC3)",978-1-5386-3852-1,,10.1109/ICAC3.2017.8318793,http://ieeexplore.ieee.org/document/8318793/,,2017-12,21/11/2018 11:52,14/04/2020 08:35,21/11/2018 11:52,01-Jul,,,,,,,,,,,IEEE,Mumbai,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2017 International Conference on Advances in Computing, Communication and Control (ICAC3)",,,,,,,,,,,,,,, VDAUFXXC,conferencePaper,2013,"Yuwen Dong; Rivera, Daniel E.; Downs, Danielle S.; Savage, Jennifer S.; Thomas, Diana M.; Collins, Linda M.",Hybrid model predictive control for optimizing gestational weight gain behavioral interventions,2013 American Control Conference,978-1-4799-0178-4 978-1-4799-0177-7 978-1-4799-0175-3,,10.1109/ACC.2013.6580124,http://ieeexplore.ieee.org/document/6580124/,"Excessive gestational weight gain (GWG) represents a major public health issue. In this paper, we pursue a control engineering approach to the problem by applying model predictive control (MPC) algorithms to act as decision policies in the intervention for assigning optimal intervention dosages. The intervention components consist of education, behavioral modification and active learning. The categorical nature of the intervention dosage assignment problem dictates the need for hybrid model predictive control (HMPC) schemes, ultimately leading to improved outcomes. The goal is to design a controller that generates an intervention dosage sequence which improves a participant's healthy eating behavior and physical activity to better control GWG. An improved formulation of self-regulation is also presented through the use of Internal Model Control (IMC), allowing greater flexibility in describing self-regulatory behavior. Simulation results illustrate the basic workings of the model and demonstrate the benefits of hybrid predictive control for optimized GWG adaptive interventions.",2013-06,21/11/2018 11:52,14/04/2020 08:35,21/11/2018 11:52,1970-1975,,,,,,,,,,,IEEE,"Washington, DC",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2013 American Control Conference (ACC),,,,,,,,,,,,,,, H28DW9TJ,conferencePaper,2015,"Shekh, Barzan; de Doncker, Elise; Prieto, Diana",Hybrid multi-threaded simulation of agent-based pandemic modeling using multiple GPUs,2015 IEEE International Conference on Bioinformatics and Biomedicine (BIBM),978-1-4673-6799-8,,10.1109/BIBM.2015.7359894,http://ieeexplore.ieee.org/document/7359894/,,2015-11,21/11/2018 11:52,14/04/2020 08:35,21/11/2018 11:52,1478-1485,,,,,,,,,,,IEEE,"Washington, DC, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 IEEE International Conference on Bioinformatics and Biomedicine (BIBM),,,,,,,,,,,,,,, RI8FLELL,journalArticle,2016,"Zhu, Kangrong; Dougherty, Robert F.; Wu, Hua; Middione, Matthew J.; Takahashi, Atsushi M.; Zhang, Tao; Pauly, John M.; Kerr, Adam B.",Hybrid-Space SENSE Reconstruction for Simultaneous Multi-Slice MRI,IEEE Transactions on Medical Imaging,,"0278-0062, 1558-254X",10.1109/TMI.2016.2531635,http://ieeexplore.ieee.org/document/7412782/,,2016-08,21/11/2018 11:52,14/04/2020 08:35,21/11/2018 11:52,1824-1836,,8,35,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6ES9WGMT,journalArticle,2016,"Zeng, Jing; Yang, Laurence T.; Ma, Jianhua; Guo, Minyi",HyperspaceFlow: A System-Level Design Methodology for Smart Space,IEEE Transactions on Emerging Topics in Computing,,2168-6750,10.1109/TETC.2015.2501846,http://ieeexplore.ieee.org/document/7331620/,,2016-10,21/11/2018 11:52,14/04/2020 08:35,21/11/2018 11:52,568-583,,4,4,,,HyperspaceFlow,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4TUXHZT8,conferencePaper,2008,"Sheppard, John W.; Kaufman, Mark A.; Wilmering, Timothy J.",IEEE standards for prognostics and health management,2008 IEEE AUTOTESTCON,978-1-4244-2225-8,,10.1109/AUTEST.2008.4662592,http://ieeexplore.ieee.org/document/4662592/,,2008-09,21/11/2018 11:52,14/04/2020 08:35,21/11/2018 11:52,97-103,,,,,,,,,,,IEEE,"Salt Lake City, UT",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEEE AUTOTESTCON 2008,,,,,,,,,,,,,,, PNISNFUU,conferencePaper,2004,"Kupinski, M.A.; Clarkson, E.",Image-quality assessment in optical tomography,2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano (IEEE Cat No. 04EX821),978-0-7803-8388-3,,10.1109/ISBI.2004.1398827,http://ieeexplore.ieee.org/document/1398827/,,2004,21/11/2018 11:52,14/04/2020 08:34,21/11/2018 11:52,1471-1474,,,2,,,,,,,,IEEE,"Arlington, VA, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano,,,,,,,,,,,,,,, NY3WVW36,conferencePaper,2017,"Sofyan, Qadavi Muhammad; Arini, M T; Rozy, Nurul Faizah",Implementation of principal component analysis method for detection of chlorine and bleach in rice,2017 5th International Conference on Cyber and IT Service Management (CITSM),978-1-5386-2739-6,,10.1109/CITSM.2017.8089236,http://ieeexplore.ieee.org/document/8089236/,,2017-08,21/11/2018 11:52,14/04/2020 08:35,21/11/2018 11:52,01-May,,,,,,,,,,,IEEE,"Denpasar, Bali, Indonesia",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 5th International Conference on Cyber and IT Service Management (CITSM),,,,,,,,,,,,,,, X5C4TRZQ,conferencePaper,2014,"Bao, Jie; Lu, Zhihui; Wu, Jie; Zhang, Shiyong; Zhong, Yiping",Implementing a novel load-aware auto scale scheme for private cloud resource management platform,2014 IEEE Network Operations and Management Symposium (NOMS),978-1-4799-0913-1,,10.1109/NOMS.2014.6838340,http://ieeexplore.ieee.org/document/6838340/,,2014-05,21/11/2018 11:52,14/04/2020 08:34,21/11/2018 11:52,01-Apr,,,,,,,,,,,IEEE,"Krakow, Poland",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NOMS 2014 - 2014 IEEE/IFIP Network Operations and Management Symposium,,,,,,,,,,,,,,, L36Z9PHF,conferencePaper,2016,"Pandey, Sudhakar; Agrawal, Deepika; Vijay, Muni",Improved MRSPIN for health monitoring,2016 International Conference on ICT in Business Industry & Government (ICTBIG),978-1-5090-5515-9,,10.1109/ICTBIG.2016.7892652,http://ieeexplore.ieee.org/document/7892652/,,2016,21/11/2018 11:52,14/04/2020 08:35,21/11/2018 11:52,01-Apr,,,,,,,,,,,IEEE,"Indore, India",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 International Conference on ICT in Business Industry & Government (ICTBIG),,,,,,,,,,,,,,, HR5YGQWA,conferencePaper,2014,"Ddin, Wakee U; Khan, Bilal M.",Improved quality of service in wireless sensor Network with mobile sink,17th IEEE International Multi Topic Conference 2014,978-1-4799-5754-5 978-1-4799-5755-2,,10.1109/INMIC.2014.7096907,http://ieeexplore.ieee.org/document/7096907/,,2014-12,21/11/2018 11:52,14/04/2020 08:34,21/11/2018 11:52,36-40,,,,,,,,,,,IEEE,"Karachi, Pakistan",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2014 IEEE 17th International Multi-Topic Conference (INMIC),,,,,,,,,,,,,,, Z7QUDJ97,journalArticle,2010,"Enholm, J.K.; Kohler, M.O.; Quesson, B.; Mougenot, C.; Moonen, C.T.W.; Sokka, S.D.",Improved Volumetric MR-HIFU Ablation by Robust Binary Feedback Control,IEEE Transactions on Biomedical Engineering,,"0018-9294, 1558-2531",10.1109/TBME.2009.2034636,http://ieeexplore.ieee.org/document/5290090/,,2010-01,21/11/2018 11:52,14/04/2020 08:34,21/11/2018 11:52,103-113,,1,57,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, S8BWSZGL,journalArticle,2015,"Alshurafa, Nabil; Eastwood, Jo-Ann; Nyamathi, Suneil; Liu, Jason J.; Xu, Wenyao; Ghasemzadeh, Hassan; Pourhomayoun, Mohammad; Sarrafzadeh, Majid",Improving Compliance in Remote Healthcare Systems Through Smartphone Battery Optimization,IEEE Journal of Biomedical and Health Informatics,,"2168-2194, 2168-2208",10.1109/JBHI.2014.2329712,http://ieeexplore.ieee.org/document/6827927/,,2015-01,21/11/2018 11:52,14/04/2020 08:34,21/11/2018 11:52,57-63,,1,19,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MQH78AIL,conferencePaper,2013,"Lu, Ta-Ping; Shih, Jui-Tien; Kittipittayakorn, Cholada; Lian, Geng-Feng",Improving outpatient service quality in department of orthopedic surgery by using collaborative approaches,Proceedings of the 2013 IEEE 17th International Conference on Computer Supported Cooperative Work in Design (CSCWD),978-1-4673-6085-2 978-1-4673-6084-5 978-1-4673-6083-8,,10.1109/CSCWD.2013.6581015,http://ieeexplore.ieee.org/document/6581015/,,2013-06,21/11/2018 11:52,14/04/2020 08:34,21/11/2018 11:52,515-520,,,,,,,,,,,IEEE,"Whistler, BC, Canada",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2013 IEEE 17th International Conference on Computer Supported Cooperative Work in Design (CSCWD),,,,,,,,,,,,,,, 8GJZFTBB,conferencePaper,2013,Da Xu; Chenguang He; Ye Li,Improving quality of experience in m-health monitoring system,2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC),978-1-4577-0216-7,,10.1109/EMBC.2013.6609990,http://ieeexplore.ieee.org/document/6609990/,,2013-07,21/11/2018 11:52,14/04/2020 08:34,21/11/2018 11:52,2271-2274,,,,,,,,,,,IEEE,Osaka,,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC),,,,,,,,,,,,,,, H3JMVF9R,conferencePaper,2011,"Stearns, Charles W.; Manjeshwar, Ravindra M.",Incorporating count-rate dependence into model-based PET scatter estimation,2011 IEEE Nuclear Science Symposium Conference Record,978-1-4673-0120-6 978-1-4673-0118-3 978-1-4673-0119-0,,10.1109/NSSMIC.2011.6153708,http://ieeexplore.ieee.org/document/6153708/,,2011-10,21/11/2018 11:52,14/04/2020 08:35,21/11/2018 11:52,3745-3747,,,,,,,,,,,IEEE,"Valencia, Spain",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2011 IEEE Nuclear Science Symposium and Medical Imaging Conference (2011 NSS/MIC),,,,,,,,,,,,,,, JR79YITR,journalArticle,2012,"Torkestani, S.S.; Sahuguede, S.; Julien-Vergonjanne, A.; Cances, J.P.",Indoor optical wireless system dedicated to healthcare application in a hospital,IET Communications,,17518628,10.1049/iet-com.2010.1116,http://digital-library.theiet.org/content/journals/10.1049/iet-com.2010.1116,,2012,21/11/2018 11:52,14/04/2020 08:35,21/11/2018 11:52,541,,5,6,,,,,,,,,,en,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, F2BT5YFE,journalArticle,2018,"Koulali, Mohammed-Amine; Koulali, Sara; Tembine, Hamidou; Kobbane, Abdellatif",Industrial Internet of Things-Based Prognostic Health Management: A Mean-Field Stochastic Game Approach,IEEE Access,,2169-3536,10.1109/ACCESS.2018.2871859,https://ieeexplore.ieee.org/document/8471104/,,2018,21/11/2018 11:52,14/04/2020 08:34,21/11/2018 11:52,54388-54395,,,6,,,Industrial Internet of Things-Based Prognostic Health Management,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, AB4I2GZA,conferencePaper,2004,"Nishida, Y.; Kitamura, K.; Motomura, Y.; Mizoguchi, H.",Infant behavior simulation based on an environmental model and a developmental behavior model*,"2004 IEEE International Conference on Systems, Man and Cybernetics (IEEE Cat. No.04CH37583)",978-0-7803-8567-2,,10.1109/ICSMC.2004.1399853,http://ieeexplore.ieee.org/document/1399853/,,2004,21/11/2018 11:52,14/04/2020 08:35,21/11/2018 11:52,1555-1560,,,2,,,,,,,,IEEE,"The Hague, Netherlands",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2004 IEEE International Conference on Systems, Man and Cybernetics (IEEE Cat. No.04CH37583)",,,,,,,,,,,,,,, C7HQPPBZ,conferencePaper,2009,"Harrington, Patrick L.; Hero, Alfred O.",Information theoretic adaptive tracking of epidemics in complex networks,"2009 47th Annual Allerton Conference on Communication, Control, and Computing (Allerton)",978-1-4244-5870-7,,10.1109/ALLERTON.2009.5394902,http://ieeexplore.ieee.org/document/5394902/,,2009-09,21/11/2018 11:52,14/04/2020 08:34,21/11/2018 11:52,523-530,,,,,,,,,,,IEEE,"Monticello, IL, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2009 47th Annual Allerton Conference on Communication, Control, and Computing (Allerton)",,,,,,,,,,,,,,, BBY9NWPC,conferencePaper,2010,"Wang, Hui; Choi, Hyeok-soo; Agoulmine, Nazim; Jamal Deen, M.; Won-Ki Hong, James",Information-based sensor tasking wireless body area networks in U-health systems,2010 International Conference on Network and Service Management,978-1-4244-8910-7,,10.1109/CNSM.2010.5691350,http://ieeexplore.ieee.org/document/5691350/,,2010-10,21/11/2018 11:52,14/04/2020 08:35,21/11/2018 11:52,517-522,,,,,,,,,,,IEEE,"Niagara Falls, ON, Canada",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2010 International Conference on Network and Service Management (CNSM),,,,,,,,,,,,,,, 4R5PNNY2,conferencePaper,2015,"Roccetti, Marco; Casari, Alice; Marfia, Gustavo",Inside Chronic Autoimmune Disease Communities: A Social Networks Perspective to Crohn's Patient Behavior and Medical Information,Proceedings of the 2015 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining 2015 - ASONAM '15,978-1-4503-3854-7,,10.1145/2808797.2808813,http://dl.acm.org/citation.cfm?doid=2808797.2808813,,2015,21/11/2018 11:52,14/04/2020 08:35,21/11/2018 11:52,1089-1096,,,,,,Inside Chronic Autoimmune Disease Communities,,,,,ACM Press,"Paris, France",en,,,,,Crossref,,,,,,Chronic autoimmune diseases; Crohn's Disease; Health; Social Networks; Well-being; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,the 2015 IEEE/ACM International Conference,,,,,,,,,,,,,,, FHU44MCD,conferencePaper,2017,"Lei, Sifan; He, Lin; Liu, Yang; Song, Dong",Integrated modular avionics anomaly detection based on symbolic time series analysis,"2017 IEEE 2nd Advanced Information Technology, Electronic and Automation Control Conference (IAEAC)",978-1-4673-8979-2,,10.1109/IAEAC.2017.8054387,http://ieeexplore.ieee.org/document/8054387/,,2017-03,21/11/2018 11:52,14/04/2020 08:34,21/11/2018 11:52,2095-2099,,,,,,,,,,,IEEE,"Chongqing, China",,,,,,Crossref,,,,,,00; 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K.",Mathematical model for predicting the state of health of transformers and service methodology for enhancing their life,2011 24th Canadian Conference on Electrical and Computer Engineering(CCECE),978-1-4244-9788-1,,10.1109/CCECE.2011.6030423,http://ieeexplore.ieee.org/document/6030423/,,2011-05,21/11/2018 11:53,14/04/2020 08:34,21/11/2018 11:53,000126-000129,,,,,,,,,,,IEEE,"Niagara Falls, ON, Canada",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2011 24th IEEE Canadian Conference on Electrical and Computer Engineering (CCECE),,,,,,,,,,,,,,, HTN8FRSS,journalArticle,2017,"Shao, Wenjia; Zhang, Hongjian; Zhou, Hongliang",Mathematical Modelling and Parameter Optimization of Fine Particle Sensors based on Laser Light Scattering,IEEE Sensors Journal,,"1530-437X, 1558-1748, 2379-9153",10.1109/JSEN.2017.2747083,http://ieeexplore.ieee.org/document/8022963/,,2017,21/11/2018 11:53,14/04/2020 08:35,21/11/2018 11:53,01-Jan,,,,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, E46FAZDL,conferencePaper,2015,"Kapur, P.K.; Gupta, Aditya; Sachdeva, Nitin",Measuring brand health,"2015 4th International Conference on Reliability, Infocom Technologies and Optimization (ICRITO) (Trends and Future Directions)",978-1-4673-7231-2,,10.1109/ICRITO.2015.7359353,http://ieeexplore.ieee.org/document/7359353/,,2015-09,21/11/2018 11:53,14/04/2020 08:34,21/11/2018 11:53,01-Jun,,,,,,,,,,,IEEE,"Noida, India",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2015 4th International Conference on Reliability, Infocom Technologies and Optimization (ICRITO) (Trends and Future Directions)",,,,,,,,,,,,,,, A5GDUFJN,conferencePaper,2015,"Kishore, P. V. V.; Kishore, S. R. C.; Kumar, E. Kiran; Kumar, K. V. V.; Aparna, P.",Medical image watermarking with DWT-BAT algorithm,2015 International Conference on Signal Processing and Communication Engineering Systems,978-1-4799-6109-2,,10.1109/SPACES.2015.7058263,http://ieeexplore.ieee.org/lpdocs/epic03/wrapper.htm?arnumber=7058263,,2015-01,21/11/2018 11:53,14/04/2020 08:34,21/11/2018 11:53,270-275,,,,,,,,,,,IEEE,"Guntur, India",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 International Conference on Signal Processing And Communication Engineering Systems (SPACES),,,,,,,,,,,,,,, KRFCQCAZ,journalArticle,2009,"Istepanian, Robert; Philip, Nada; Martini, Maria",Medical QoS provision based on reinforcement learning in ultrasound streaming over 3.5G wireless systems,IEEE Journal on Selected Areas in Communications,,0733-8716,10.1109/JSAC.2009.090517,http://ieeexplore.ieee.org/document/4909291/,,2009-05,21/11/2018 11:53,14/04/2020 08:34,21/11/2018 11:53,566-574,,4,27,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RZ29E4Y2,journalArticle,2017,"Vega Cotto, Samuel; Lee, Wei-Jen",Microgrid Modular Design for Tribal Healthcare Facilities: Kayenta Health Center PV System Case Study,IEEE Transactions on Industry Applications,,"0093-9994, 1939-9367",10.1109/TIA.2017.2725818,http://ieeexplore.ieee.org/document/7973093/,,2017-11,21/11/2018 11:53,14/04/2020 08:35,21/11/2018 11:53,5121-5129,,6,53,,,Microgrid Modular Design for Tribal Healthcare Facilities,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TQPALC4X,conferencePaper,2017,"Cotto, Samuel Vega; Lee, Wei-Jen",Microgrid modular design for tribal healthcare facilities: Kayenta health center used as guidance for concept model for Navajo Nation,2017 IEEE Industry Applications Society Annual Meeting,978-1-5090-4894-6,,10.1109/IAS.2017.8101705,http://ieeexplore.ieee.org/document/8101705/,,2017-10,21/11/2018 11:53,14/04/2020 08:34,21/11/2018 11:53,01-Aug,,,,,,Microgrid modular design for tribal healthcare facilities,,,,,IEEE,"Cincinnati, OH",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 IEEE Industry Applications Society Annual Meeting,,,,,,,,,,,,,,, ZPSWRIGT,conferencePaper,2012,"Sampathkumar, Hariprasad; Luo, Bo; Chen, Xue-wen",Mining Adverse Drug Side-Effects from Online Medical Forums,"2012 IEEE Second International Conference on Healthcare Informatics, Imaging and Systems Biology",978-0-7695-4921-7 978-1-4673-4803-4,,10.1109/HISB.2012.75,http://ieeexplore.ieee.org/document/6366240/,,2012-09,21/11/2018 11:53,14/04/2020 08:35,21/11/2018 11:53,150-150,,,,,,,,,,,IEEE,"La Jolla, CA, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2012 IEEE Second International Conference on Healthcare Informatics, Imaging and Systems Biology (HISB)",,,,,,,,,,,,,,, 5N5PEQDA,conferencePaper,2016,"Wei, Xiaohui; Zou, Wenyang; Gao, Shang","Mining Electronic Physical Records, a trial",2016 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining (ASONAM),978-1-5090-2846-7,,10.1109/ASONAM.2016.7752369,http://ieeexplore.ieee.org/document/7752369/,,2016-08,21/11/2018 11:53,14/04/2020 08:35,21/11/2018 11:53,1038-1043,,,,,,,,,,,IEEE,"San Francisco, CA, USA",,,,,,Crossref,,,,,,(EPR); electronic; physical; records; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining (ASONAM),,,,,,,,,,,,,,, EK6H7R9L,journalArticle,2017,"Islam, MD. Mofijul; Razzaque, MD. Abdur; Hassan, Mohammad Mehedi; Ismail, Walaa Nagy; Song, Biao",Mobile Cloud-Based Big Healthcare Data Processing in Smart Cities,IEEE Access,,2169-3536,10.1109/ACCESS.2017.2707439,http://ieeexplore.ieee.org/document/7933943/,,2017,21/11/2018 11:53,14/04/2020 08:34,21/11/2018 11:53,11887-11899,,,5,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UAX98NPC,conferencePaper,2014,"Birgani, Yasna Ghanbari; Javan, Nastooh Taheri; Tourani, Mohsen",Mobility enhancement of patients body monitoring based on WBAN with multipath routing,2014 2nd International Conference on Information and Communication Technology (ICoICT),978-1-4799-3581-9 978-1-4799-3580-2,,10.1109/ICoICT.2014.6914053,http://ieeexplore.ieee.org/document/6914053/,,2014-05,21/11/2018 11:53,14/04/2020 08:34,21/11/2018 11:53,127-132,,,,,,,,,,,IEEE,"Bandung, Indonesia",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2014 2nd International Conference on Information and Communication Technology (ICoICT),,,,,,,,,,,,,,, 2F792J47,conferencePaper,2017,"Breda, A. C. L. F.; Marques, L. M. F.; Holanda, L. R.",Modeling ambulatory care to obtain a balance between quantity and quality provided,2017 IEEE International Conference on Industrial Engineering and Engineering Management (IEEM),978-1-5386-0948-4,,10.1109/IEEM.2017.8290257,http://ieeexplore.ieee.org/document/8290257/,"It is common for organizations to achieve high productivity in order to increase their profit, but for the health sector, in addition to quantity of care, quality of care is important to customers. However, it is common to see poor quality in medical care centers caused by a number of variables. After analyzing a Brazilian outpatient clinic, the short duration of medical care observed referred to low quality of care. In this way, the article performed a mathematical modeling that seeks a satisfactory solution for decision-making when the quality and quantity of care are balanced. In order to perform this modeling, the theory of endogenous growth was applied using the production function, Markovian decision process and the Cobb-Douglas function. The satisfactory solution found can be adopted for other centers.",2017-12,21/11/2018 11:53,14/04/2020 08:34,21/11/2018 11:53,2073-2077,,,,,,,,,,,IEEE,Singapore,,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 IEEE International Conference on Industrial Engineering and Engineering Management (IEEM),,,,,,,,,,,,,,, IZG9RWSL,conferencePaper,2018,"Peng, Qi; Guo, Ying-Qing; Sun, Hao",Modeling and Fault Diagnosis of Aero-engine Lubricating Oil System,2018 37th Chinese Control Conference (CCC),978-988-15639-5-8,,10.23919/ChiCC.2018.8482947,https://ieeexplore.ieee.org/document/8482947/,,2018-07,21/11/2018 11:53,14/04/2020 08:35,21/11/2018 11:53,5907-5912,,,,,,,,,,,IEEE,Wuhan,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2018 37th Chinese Control Conference (CCC),,,,,,,,,,,,,,, 6CAN6YWS,conferencePaper,2013,"Shatnawi, M.; Lazarova-Molnar, S.; Zaki, N.",Modeling and simulation of epidemic spread: Recent advances,2013 9th International Conference on Innovations in Information Technology (IIT),978-1-4673-6203-0,,10.1109/Innovations.2013.6544404,http://ieeexplore.ieee.org/document/6544404/,,2013-03,21/11/2018 11:53,14/04/2020 08:35,21/11/2018 11:53,118-123,,,,,,Modeling and simulation of epidemic spread,,,,,IEEE,Abu Dhabi,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2013 9th International Conference on Innovations in Information Technology (IIT),,,,,,,,,,,,,,, PC45CXMJ,journalArticle,2018,"Brogan, Paul V.; Best, Robert; Morrow, John; Gharavi, Hani; Kubik, Marek",Modelling optimisation and protection outcomes from distributed assets controlled to reduce a PMU based multi-objective cost function,The Journal of Engineering,,2051-3305,10.1049/joe.2018.0241,http://digital-library.theiet.org/content/journals/10.1049/joe.2018.0241,,01/10/2018,21/11/2018 11:53,14/04/2020 08:34,21/11/2018 11:53,891-895,,15,2018,,,,,,,,,,en,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UYMC7NS9,conferencePaper,2014,"Azeem, Saniya; Sharan, Preeta; Talabattula, Srinivas",MOEMS based photonic crystal sensor for structural health monitoring system,"2014 IEEE International Conference on Advanced Communications, Control and Computing Technologies",978-1-4799-3914-5 978-1-4799-3913-8,,10.1109/ICACCCT.2014.7019244,http://ieeexplore.ieee.org/document/7019244/,,2014-05,21/11/2018 11:53,14/04/2020 08:34,21/11/2018 11:53,999-1002,,,,,,,,,,,IEEE,"Ramanathapuram, India",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2014 International Conference on Advanced Communication, Control and Computing Technologies (ICACCCT)",,,,,,,,,,,,,,, WWEBZVDS,journalArticle,2013,"Zhou, Xichuan; Li, Qin; Zhu, Zhenglin; Zhao, Han; Tang, Hao; Feng, Yujie",Monitoring Epidemic Alert Levels by Analyzing Internet Search Volume,IEEE Transactions on Biomedical Engineering,,"0018-9294, 1558-2531",10.1109/TBME.2012.2228264,http://ieeexplore.ieee.org/document/6357231/,,2013-02,21/11/2018 11:53,14/04/2020 08:35,21/11/2018 11:53,446-452,,2,60,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VT7TPI4J,conferencePaper,2006,"Rougier, Caroline; Meunier, Jean; St-Arnaud, Alain; Rousseau, Jacqueline",Monocular 3D Head Tracking to Detect Falls of Elderly People,2006 International Conference of the IEEE Engineering in Medicine and Biology Society,978-1-4244-0032-4,,10.1109/IEMBS.2006.260829,http://ieeexplore.ieee.org/document/4463271/,,2006-08,21/11/2018 11:53,14/04/2020 08:35,21/11/2018 11:53,6384-6387,,,,,,,,,,,IEEE,"New York, NY",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Conference Proceedings. Annual International Conference of the IEEE Engineering in Medicine and Biology Society,,,,,,,,,,,,,,, 2M8ST5GS,conferencePaper,2004,"Ramos, M.; Ferrer, S.; Villaescusa, J.I.; Verdu, G.; Campayo, J.M.",Monte Carlo image reconstruction of a mammographic phantom,The 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society,978-0-7803-8439-2,,10.1109/IEMBS.2004.1403452,http://ieeexplore.ieee.org/document/1403452/,,2004,21/11/2018 11:53,14/04/2020 08:35,21/11/2018 11:53,1467-1470,,,3,,,,,,,,IEEE,"San Francisco, CA, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society,,,,,,,,,,,,,,, GLM5ZULU,conferencePaper,2011,"Sihver, L.; Puchalska, M.; Sato, T.; Berger, T.; Reitz, G.",Monte carlo simulations of MATROSHKA experiment outside ISS,2011 Aerospace Conference,978-1-4244-7350-2,,10.1109/AERO.2011.5747252,http://ieeexplore.ieee.org/document/5747252/,,2011-03,21/11/2018 11:53,14/04/2020 08:35,21/11/2018 11:53,01-Nov,,,,,,,,,,,IEEE,"Big Sky, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2011 IEEE Aerospace Conference,,,,,,,,,,,,,,, W28HEKTS,conferencePaper,2012,"Abo-Hamad, Waleed; Arisha, Amr",Multi-criteria framework for emergency department in Irish hospital,Proceedings Title: Proceedings of the 2012 Winter Simulation Conference (WSC),978-1-4673-4782-2 978-1-4673-4779-2 978-1-4673-4780-8 978-1-4673-4781-5,,10.1109/WSC.2012.6465074,http://ieeexplore.ieee.org/document/6465074/,"Health research is one of these priorities in every economy and through this research an emphasis will be put on translational research in the context of more sustainable and efficient healthcare system (translation of operations management practices to clinical applications). Healthcare systems in general and Emergency Departments in particular around the world are facing enormous challenges in meeting the increasingly conflicting objectives of providing wide accessibility and efficiency while delivering high quality and prompt services. The proposed framework integrates simulation modeling, balanced scorecard, and multi-criteria decision analysis aiming to provide a decision support system to emergency department managers. Simulation outputs are aggregated using analytic hierarchy process (AHP) to provide marginal performance regarding the achievement of the defined strategic as well as tactical and operational objectives. Communicating the significance of investigated strategies has encouraged managers to implement the framework recommendations in the emergency department within the hospital partner.",2012-12,21/11/2018 11:53,14/04/2020 08:34,21/11/2018 11:53,01-Dec,,,,,,,,,,,IEEE,"Berlin, Germany",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 Winter Simulation Conference - (WSC 2012),,,,,,,,,,,,,,, RIXCIM8T,journalArticle,2018,"Lazzerini, Beatrice; Pistolesi, Francesco",Multiobjective Personnel Assignment Exploiting Workers’ Sensitivity to Risk,"IEEE Transactions on Systems, Man, and Cybernetics: Systems",,"2168-2216, 2168-2232",10.1109/TSMC.2017.2665349,https://ieeexplore.ieee.org/document/7864465/,,2018-08,21/11/2018 11:53,14/04/2020 08:34,21/11/2018 11:53,1267-1282,,8,48,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GQ9CHSW9,conferencePaper,2015,"Lin, Chien; Ye, Jiun-Hau; Yu, Cheng-Juei; Weng, Ming-Lung; Chang, Juiwen; Wu, Tsung-Lin; Hsiao, Morris H.; Lin, Grace",Multi-objective Value-Driven Smart Building Management Solutions,2015 International Conference on Cloud Computing and Big Data (CCBD),978-1-4673-8350-9,,10.1109/CCBD.2015.52,http://ieeexplore.ieee.org/document/7450561/,,2015-11,21/11/2018 11:53,14/04/2020 08:34,21/11/2018 11:53,260-263,,,,,,,,,,,IEEE,"Shanghai, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 International Conference on Cloud Computing and Big Data (CCBD),,,,,,,,,,,,,,, TLHX7VGC,journalArticle,2016,"Cicalo, Sergio; Mazzotti, Matteo; Moretti, Simone; Tralli, Velio; Chiani, Marco",Multiple Video Delivery in m-Health Emergency Applications,IEEE Transactions on Multimedia,,"1520-9210, 1941-0077",10.1109/TMM.2016.2597001,http://ieeexplore.ieee.org/document/7527665/,,2016-10,21/11/2018 11:53,14/04/2020 08:34,21/11/2018 11:53,1988-2001,,10,18,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Y9KKVQEX,conferencePaper,2012,"Moghaddass, Ramin; Zuo, Ming J.",Multi-state degradation analysis for a condition monitored device with unobservable states,"2012 International Conference on Quality, Reliability, Risk, Maintenance, and Safety Engineering",978-1-4673-0788-8 978-1-4673-0786-4 978-1-4673-0787-1,,10.1109/ICQR2MSE.2012.6246295,http://ieeexplore.ieee.org/document/6246295/,,2012-06,21/11/2018 11:53,14/04/2020 08:34,21/11/2018 11:53,549-554,,,,,,,,,,,IEEE,"Chengdu, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2012 International Conference on Quality, Reliability, Risk, Maintenance, and Safety Engineering (QR2MSE)",,,,,,,,,,,,,,, BC3UQGZ8,conferencePaper,2013,"Burstein, F.; De Silva, Daswin; Jelinek, H. F.; Stranieri, A.",Multivariate Data-Driven Decision Guidance for clinical scientists,2013 IEEE 29th International Conference on Data Engineering Workshops (ICDEW),978-1-4673-5304-5 978-1-4673-5303-8 978-1-4673-5302-1,,10.1109/ICDEW.2013.6547449,http://ieeexplore.ieee.org/document/6547449/,,2013-04,21/11/2018 11:53,14/04/2020 08:34,21/11/2018 11:53,193-199,,,,,,,,,,,IEEE,"Brisbane, QLD",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2013 IEEE 29th International Conference on Data Engineering Workshops (ICDEW 2013),,,,,,,,,,,,,,, YK2D3EFQ,conferencePaper,2014,"Gelenbe, Erol; Han, Qing",Near-optimal emergency evacuation with rescuer allocation,2014 IEEE International Conference on Pervasive Computing and Communication Workshops (PERCOM WORKSHOPS),978-1-4799-2736-4,,10.1109/PerComW.2014.6815224,http://ieeexplore.ieee.org/document/6815224/,,2014-03,21/11/2018 11:53,14/04/2020 08:34,21/11/2018 11:53,314-319,,,,,,,,,,,IEEE,"Budapest, Hungary",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2014 IEEE International Conference on Pervasive Computing and Communication Workshops (PERCOM WORKSHOPS),,,,,,,,,,,,,,, URMIAZ7E,conferencePaper,2014,"Chai, Rong; Wang, Panpan; Huang, Zheng; Su, Cui",Network lifetime maximization based joint resource optimization for Wireless Body Area Networks,"2014 IEEE 25th Annual International Symposium on Personal, Indoor, and Mobile Radio Communication (PIMRC)",978-1-4799-4912-0,,10.1109/PIMRC.2014.7136329,http://ieeexplore.ieee.org/document/7136329/,,2014-09,21/11/2018 11:53,14/04/2020 08:34,21/11/2018 11:53,1088-1092,,,,,,,,,,,IEEE,"Washington DC, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2014 IEEE 25th Annual International Symposium on Personal, Indoor, and Mobile Radio Communications (PIMRC)",,,,,,,,,,,,,,, 5BC67W2W,conferencePaper,2013,"Balouchestani, M.; Raahemifar, K.; Krishnan, S.",New sampling approach for wireless ECG systems with compressed sensing theory,2013 IEEE International Symposium on Medical Measurements and Applications (MeMeA),978-1-4673-5197-3 978-1-4673-5195-9 978-1-4673-5196-6,,10.1109/MeMeA.2013.6549738,http://ieeexplore.ieee.org/document/6549738/,,2013-05,21/11/2018 11:53,14/04/2020 08:34,21/11/2018 11:53,213-218,,,,,,,,,,,IEEE,"Gatineau, QC",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2013 IEEE International Symposium on Medical Measurements and Applications (MeMeA),,,,,,,,,,,,,,, VQDU4CU2,conferencePaper,2014,"Larkin, Chris; Valand, Reena; Syrysko, Paul; Harris, Roy; Shaw, Dominick; Brown, Michael; Pinchin, James; Benning, Kelly; Sharples, Sarah; Blakey, John","'Night Shift': A Task Simulation to Improve On-Call Prioritisation, Self-Management, Communication, and Route Planning Skills",2014 International Conference on Interactive Technologies and Games,978-1-4799-6795-7,,10.1109/iTAG.2014.11,http://ieeexplore.ieee.org/document/6990191/,,2014-10,21/11/2018 11:53,14/04/2020 08:34,21/11/2018 11:53,59-62,,,,,,'Night Shift',,,,,IEEE,"Nottingham, United Kingdom",,,,,,Crossref,,,"

International Conference on Interactive Technologies and Games (iTAG), Nottingham, ENGLAND, OCT 16-17, 2014

",,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2014 International Conference on Interactive Technologies and Games (iTAG),,,,,,,,,,,,,,, 8B2N2KDS,conferencePaper,2016,"Tonchev, Krasimir; Koleva, Pavlina; Manolova, Agata; Tsenov, Georgi; Poulkov, Vladimir",Non-intrusive sleep analyzer for real time detection of sleep anomalies,2016 39th International Conference on Telecommunications and Signal Processing (TSP),978-1-5090-1288-6,,10.1109/TSP.2016.7760906,http://ieeexplore.ieee.org/document/7760906/,,2016-06,21/11/2018 11:53,14/04/2020 08:35,21/11/2018 11:53,400-404,,,,,,,,,,,IEEE,"Vienna, Austria",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 39th International Conference on Telecommunications and Signal Processing (TSP),,,,,,,,,,,,,,, 2R87REME,conferencePaper,2014,"Silva, Luis A. Bastiao; Ribeiro, Luis; Costa, Carlos; Oliveira, Jose Luis; Santos, Milton",Normalizing medical imaging archives for dose quality assurance and productivity auditing,2014 IEEE International Symposium on Medical Measurements and Applications (MeMeA),978-1-4799-2921-4 978-1-4799-2920-7,,10.1109/MeMeA.2014.6860112,http://ieeexplore.ieee.org/document/6860112/,,2014-06,21/11/2018 11:53,14/04/2020 08:35,21/11/2018 11:53,01-Jun,,,,,,,,,,,IEEE,"Lisboa, Portugal",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2014 IEEE International Symposium on Medical Measurements and Applications (MeMeA),,,,,,,,,,,,,,, 7ZHCGG6Q,conferencePaper,2013,"Zhang, Hongyuan; Hao, Aizhi; Liao, Hanlin",A health status evaluation based on minimal path about the destruction equipment of high-risk hazardous goods,"2013 International Conference on Quality, Reliability, Risk, Maintenance, and Safety Engineering (QR2MSE)",978-1-4799-1016-8 978-1-4799-1014-4,,10.1109/QR2MSE.2013.6625941,http://ieeexplore.ieee.org/document/6625941/,,2013-07,21/11/2018 11:53,14/04/2020 08:35,21/11/2018 11:53,1863-1866,,,,,,,,,,,IEEE,"Chengdu, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2013 International Conference on Quality, Reliability, Risk, Maintenance, and Safety Engineering (QR2MSE)",,,,,,,,,,,,,,, LYUIX8FW,conferencePaper,2011,"Xu, Haizhen; Li, Guomin; Dong, Yanhui; Li, Ming; Zhang, Shouquan",Comparative Study of Numerical Delineation for Wellhead Protection Area under Steady-State and Transient State,2011 5th International Conference on Bioinformatics and Biomedical Engineering,978-1-4244-5088-6,,10.1109/icbbe.2011.5780860,http://ieeexplore.ieee.org/document/5780860/,,2011-05,21/11/2018 11:53,14/04/2020 08:35,21/11/2018 11:53,01-Apr,,,,,,,,,,,IEEE,"Wuhan, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2011 5th International Conference on Bioinformatics and Biomedical Engineering (iCBBE),,,,,,,,,,,,,,, HK8VBVFE,conferencePaper,2011,"Deyin, Huang; Qian, Zhang; Jing, Zhang; Mao, Liu",Notice of Retraction Modeling of Occupational Exposure to Benzene and Health Risk of Workers in Styrene Production,2011 5th International Conference on Bioinformatics and Biomedical Engineering,978-1-4244-5088-6 978-1-4244-5089-3,,10.1109/icbbe.2011.5781265,http://ieeexplore.ieee.org/document/5781265/,,2011-05,21/11/2018 11:53,14/04/2020 08:34,21/11/2018 11:53,01-May,,,,,,,,,,,IEEE,Wuhan,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2011 5th International Conference on Bioinformatics and Biomedical Engineering,,,,,,,,,,,,,,, IB68D5VK,conferencePaper,2010,"Li, Hui; Zhang, Fujian",Stochastic process model of vehicle loads based on structural health monitoring data and maximum prediction of general renewal processes,2010 International Conference on Computer Application and System Modeling (ICCASM 2010),978-1-4244-7235-2,,10.1109/ICCASM.2010.5619257,http://ieeexplore.ieee.org/document/5619257/,,2010-10,21/11/2018 11:53,14/04/2020 08:34,21/11/2018 11:53,V4-704-V4-708,,,,,,,,,,,IEEE,"Taiyuan, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2010 International Conference on Computer Application and System Modeling (ICCASM 2010),,,,,,,,,,,,,,, 7GI98KU5,conferencePaper,2009,"Fan, Jiang; Chun, Wang; Zhongwei, Liang; Yidan, Hu",Numerical Simulation of Benzene Flow Indoor of Car-Body,2009 International Conference on Energy and Environment Technology,978-0-7695-3819-8,,10.1109/ICEET.2009.566,http://ieeexplore.ieee.org/document/5367073/,,2009,21/11/2018 11:53,14/04/2020 08:34,21/11/2018 11:53,419-422,,,,,,,,,,,IEEE,"Guilin, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2009 International Conference on Energy and Environment Technology,,,,,,,,,,,,,,, 3K4P28KL,conferencePaper,2009,"Yu, Mei-chun; Zhang, Deng-chun",Numerical Simulation on Smoke of Kitchen in an Apartment Unit,2009 International Conference on Energy and Environment Technology,978-0-7695-3819-8,,10.1109/ICEET.2009.567,http://ieeexplore.ieee.org/document/5367077/,,2009,21/11/2018 11:53,14/04/2020 08:35,21/11/2018 11:53,423-426,,,,,,,,,,,IEEE,"Guilin, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2009 International Conference on Energy and Environment Technology,,,,,,,,,,,,,,, L5KBZXBQ,conferencePaper,2016,"Gomathi, C.; Santhiyakumari, N.",OFSR: An Optimized Fuzzy Based Swarm Routing for Wireless Body Area Networks,2016 3rd International Conference on Signal Processing and Integrated Networks (SPIN),978-1-4673-9197-9,,10.1109/SPIN.2016.7566748,http://ieeexplore.ieee.org/document/7566748/,,2016-02,21/11/2018 11:53,14/04/2020 08:34,21/11/2018 11:53,507-512,,,,,,OFSR,,,,,IEEE,"Noida, Delhi NCR, India",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 3rd International Conference on Signal Processing and Integrated Networks (SPIN),,,,,,,,,,,,,,, HYZHMHE8,conferencePaper,2016,"Qiu, Yaxing; Yang, Hemin; Huang, Anpeng; Jiao, Bingli",On design of Interference Self-Coordination (ISC) solution to enable mHealth services in HetNets,2016 IEEE International Conference on Communications (ICC),978-1-4799-6664-6,,10.1109/ICC.2016.7511388,http://ieeexplore.ieee.org/document/7511388/,,2016-05,21/11/2018 11:53,14/04/2020 08:35,21/11/2018 11:53,01-Jun,,,,,,,,,,,IEEE,"Kuala Lumpur, Malaysia",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ICC 2016 - 2016 IEEE International Conference on Communications,,,,,,,,,,,,,,, RS97N7ZI,journalArticle,2013,"Bilal, Kashif; Manzano, Marc; Khan, Samee U.; Calle, Eusebi; Keqin Li; Zomaya, Albert Y.",On the Characterization of the Structural Robustness of Data Center Networks,IEEE Transactions on Cloud Computing,,2168-7161,10.1109/TCC.2013.6,http://ieeexplore.ieee.org/document/6604388/,,2013-01,21/11/2018 11:53,14/04/2020 08:34,21/11/2018 11:53,01-Jan,,1,1,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VG2HNP26,conferencePaper,2015,"Ghamlouch, Houda; Fouladirad, Mitra; Grall, Antoine",On the use of jump-diffusion process for maintenance decision-making: A first step,2015 Annual Reliability and Maintainability Symposium (RAMS),978-1-4799-6703-2,,10.1109/RAMS.2015.7105099,http://ieeexplore.ieee.org/document/7105099/,,2015-01,21/11/2018 11:53,14/04/2020 08:34,21/11/2018 11:53,01-Jun,,,,,,On the use of jump-diffusion process for maintenance decision-making,,,,,IEEE,"Palm Harbor, FL, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 Annual Reliability and Maintainability Symposium (RAMS),,,,,,,,,,,,,,, AJ2YJD6C,conferencePaper,2017,"Kim, Woongrae; Liu, Taizhi; Milor, Linda",On-line monitoring of system health using on-chip SRAMs as a wearout sensor,2017 IEEE 23rd International Symposium on On-Line Testing and Robust System Design (IOLTS),978-1-5386-0352-9,,10.1109/IOLTS.2017.8046230,http://ieeexplore.ieee.org/document/8046230/,,2017-07,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,253-258,,,,,,,,,,,IEEE,"Thessaloniki, Greece",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 IEEE 23rd International Symposium on On-Line Testing and Robust System Design (IOLTS),,,,,,,,,,,,,,, STNSPKZH,conferencePaper,2012,"Kannan, Srinivasan; Sarma, P. Sankara",Operational research of workload using time and motion of health workers in Kerala,2012 5th International Conference on BioMedical Engineering and Informatics,978-1-4673-1184-7 978-1-4673-1183-0 978-1-4673-1182-3,,10.1109/BMEI.2012.6513045,http://ieeexplore.ieee.org/document/6513045/,,2012-10,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,1213-1216,,,,,,,,,,,IEEE,"Chongqing, China",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 5th International Conference on Biomedical Engineering and Informatics (BMEI),,,,,,,,,,,,,,, MRFAQAYF,conferencePaper,2012,"Yokouchi, Mitsuko; Aoki, Setsuko; Sang, HaiXia; Zhao, Run; Takakuwa, Soemon",Operations analysis and appointment scheduling for an outpatient chemotherapy department,Proceedings Title: Proceedings of the 2012 Winter Simulation Conference (WSC),978-1-4673-4782-2 978-1-4673-4779-2 978-1-4673-4780-8 978-1-4673-4781-5,,10.1109/WSC.2012.6464990,http://ieeexplore.ieee.org/document/6464990/,,2012-12,21/11/2018 11:54,14/04/2020 08:35,21/11/2018 11:54,01-Dec,,,,,,,,,,,IEEE,"Berlin, Germany",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 Winter Simulation Conference - (WSC 2012),,,,,,,,,,,,,,, NAQZPK9E,conferencePaper,2008,"Dae-Ki Cho; Seung-Hoon Lee; Chang, Alexander; Massey, Tammara; Chia-Wei Chang; Min-Hsieh Tsai; Sarrafzadeh, Majid; Gerla, Mario",Opportunistic medical monitoring using bluetooth P2P networks,"2008 International Symposium on a World of Wireless, Mobile and Multimedia Networks",978-1-4244-2099-5,,10.1109/WOWMOM.2008.4594895,http://ieeexplore.ieee.org/document/4594895/,,2008-06,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,01-Jun,,,,,,,,,,,IEEE,"Newport Beach, CA, USA",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2008 International Symposium on a World of Wireless, Mobile and Multimedia Networks (WOWMOM)",,,,,,,,,,,,,,, B9QYIC5J,conferencePaper,2017,"Marimuthu, A.; Gnanambal, K.; Priyanka, R.",Optimal allocation and sizing of DG in a radial distribution system using whale optimization algorithm,2017 International Conference on Innovations in Green Energy and Healthcare Technologies (IGEHT),978-1-5090-5778-8,,10.1109/IGEHT.2017.8093979,http://ieeexplore.ieee.org/document/8093979/,,2017-03,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,01-May,,,,,,,,,,,IEEE,"Coimbatore, India",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 International Conference on Innovations in Green Energy and Healthcare Technologies (IGEHT),,,,,,,,,,,,,,, K5XBKYPJ,conferencePaper,2016,"Cui, Tiansong; Chen, Shuang; Wang, Yanzhi; Zhu, Qi; Nazarian, Shahin; Pedram, Massoud",Optimal co-scheduling of HVAC control and battery management for energy-efficient buildings considering state-of-health degradation,2016 21st Asia and South Pacific Design Automation Conference (ASP-DAC),978-1-4673-9569-4,,10.1109/ASPDAC.2016.7428105,http://ieeexplore.ieee.org/document/7428105/,,2016-01,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,775-780,,,,,,,,,,,IEEE,"Macao, Macao",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 21st Asia and South Pacific Design Automation Conference (ASP-DAC),,,,,,,,,,,,,,, HSMN3CNN,conferencePaper,2012,Chun Su; Jinyun Shen,Optimal maintenance policies for multi-state deteriorating product based on remanufacturability,Proceedings of the IEEE 2012 Prognostics and System Health Management Conference (PHM-2012 Beijing),978-1-4577-1911-0 978-1-4577-1909-7 978-1-4577-1910-3,,10.1109/PHM.2012.6228961,http://ieeexplore.ieee.org/document/6228961/,,2012-05,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,01-May,,,,,,,,,,,IEEE,"Beijing, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 Prognostics and System Health Management Conference (PHM),,,,,,,,,,,,,,, CWTU27XD,conferencePaper,2010,"AlDurgam, Mohammad M.; Duffuaa, Salih O.",Optimal maintenance policies for three-states POMDP with quality measurement errors,2010 IEEE International Conference on Industrial Engineering and Engineering Management,978-1-4244-8501-7,,10.1109/IEEM.2010.5674294,http://ieeexplore.ieee.org/document/5674294/,,2010-12,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,2239-2243,,,,,,,,,,,IEEE,"Macao, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,EM),,,,,,,,,,,,,,, K5CKH76A,journalArticle,2011,"He, Yifeng; Zhu, Wenwu; Guan, Ling",Optimal Resource Allocation for Pervasive Health Monitoring Systems with Body Sensor Networks,IEEE Transactions on Mobile Computing,,1536-1233,10.1109/TMC.2011.83,http://ieeexplore.ieee.org/document/5765966/,,2011-11,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,1558-1575,,11,10,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, D2VFP8NX,conferencePaper,2015,"Liu, Bin; Yu, Sucheng; Chenz, Chang Wen",Optimal resource allocation in energy harvesting-powered body sensor networks,2015 2nd International Symposium on Future Information and Communication Technologies for Ubiquitous HealthCare (Ubi-HealthTech),978-1-4799-6168-9,,10.1109/Ubi-HealthTech.2015.7203355,http://ieeexplore.ieee.org/document/7203355/,,2015-05,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,01-May,,,,,,,,,,,IEEE,"Beijing, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 2nd International Symposium on Future Information and Communication Technologies for Ubiquitous HealthCare (Ubi-HealthTech),,,,,,,,,,,,,,, 2B9H9PEZ,conferencePaper,2016,"Chamov, Ivan; Ranieri, Juri; Vetterli, Martin; de Weck, Olivier L.",Optimal sensor architecture selection for health management of complex systems,2016 IEEE Aerospace Conference,978-1-4673-7676-1,,10.1109/AERO.2016.7500713,http://ieeexplore.ieee.org/document/7500713/,,2016-03,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,01-Aug,,,,,,,,,,,IEEE,"Big Sky, MT, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 IEEE Aerospace Conference,,,,,,,,,,,,,,, J2QG4AXF,journalArticle,2016,"Orozco, Oscar Arley; Llano, Gonzalo",Optimal Speed Advisory: a Vehicular Networks Application focused on decreasing CO2 emissions,IEEE Latin America Transactions,,1548-0992,10.1109/TLA.2016.7555240,http://ieeexplore.ieee.org/document/7555240/,,2016-06,21/11/2018 11:54,14/04/2020 08:35,21/11/2018 11:54,2693-2699,,6,14,,,Optimal Speed Advisory,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, G9VTZGS5,conferencePaper,2000,"Pavlopoulos, S.; Istepanian, R.S.H.; Kyriacou, E.; Koutsouris, D.",Optimal wavelet biosignal compression for mobile multi-purpose telemedicine,Proceedings 2000 IEEE EMBS International Conference on Information Technology Applications in Biomedicine. ITAB-ITIS 2000. Joint Meeting Third IEEE EMBS International Conference on Information Technology Applications in Biomedicine (ITAB'00). Third Works,978-0-7803-6449-3,,10.1109/ITAB.2000.892360,http://ieeexplore.ieee.org/document/892360/,,2000,21/11/2018 11:54,14/04/2020 08:35,21/11/2018 11:54,113,,,,,,,,,,,IEEE,"Arlington, VA, USA",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2000 IEEE EMBS International Conference on Information Technology Applications in Biomedicine. ITAB-ITIS 2000. Joint Meeting Third IEEE EMBS International Conference on Information Technology Applications in Biomedicine (ITAB'00). Third Workshop of the International Telemedical Information Society (ITIS'00),,,,,,,,,,,,,,, V44UT4LR,journalArticle,2011,"Qiao, Guofu; Liu, Tiejun; Hong, Yi; Ou, Jinping",Optimization Design of a Corrosion Monitoring Sensor by FEM for RC Structures,IEEE Sensors Journal,,"1530-437X, 1558-1748",10.1109/JSEN.2011.2112644,http://ieeexplore.ieee.org/document/5710574/,,2011-09,21/11/2018 11:54,14/04/2020 08:35,21/11/2018 11:54,2111-2112,,9,11,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JZN9GA7V,journalArticle,2006,"Lum, M.J.H.; Rosen, J.; Sinanan, M.N.; Hannaford, B.",Optimization of a Spherical Mechanism for a Minimally Invasive Surgical Robot: Theoretical and Experimental Approaches,IEEE Transactions on Biomedical Engineering,,0018-9294,10.1109/TBME.2006.875716,http://ieeexplore.ieee.org/document/1643416/,,2006-07,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,1440-1445,,7,53,,,Optimization of a Spherical Mechanism for a Minimally Invasive Surgical Robot,,,,,,,en,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, U7626HS7,conferencePaper,2012,"Dan'azumi, Salisu; Shamsudin, Supiah",Optimization of active to permanent pool volumes ratio for wet ponds in tropical catchments,2012 International Conference on Innovation Management and Technology Research,978-1-4673-0654-6 978-1-4673-0655-3 978-1-4673-0653-9,,10.1109/ICIMTR.2012.6236417,http://ieeexplore.ieee.org/document/6236417/,,2012-05,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,353-356,,,,,,,,,,,IEEE,"Malacca, Malaysia",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 International Conference on Innovation Management and Technology Research (ICIMTR),,,,,,,,,,,,,,, Y2LHNDCK,conferencePaper,2003,"Frisch, P.H.; Ling, C.C.; Lui, W.",Optimization of biomedical engineering within a comprehensive cancer center,Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE Cat. No.03CH37439),978-0-7803-7789-9,,10.1109/IEMBS.2003.1280928,http://ieeexplore.ieee.org/document/1280928/,,2003,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,3586-3589,,,,,,,,,,,IEEE,"Cancun, Mexico",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society,,,,,,,,,,,,,,, KHJ3EB4X,conferencePaper,2014,"Minimol, V. K; Shaji, R. S.",Optimization of scheduling and decision making in elderly homecare system using particle swarm optimization,"2014 International Conference on Control, Instrumentation, Communication and Computational Technologies (ICCICCT)",978-1-4799-4190-2 978-1-4799-4191-9 978-1-4799-4193-3 978-1-4799-4192-6,,10.1109/ICCICCT.2014.6992975,http://ieeexplore.ieee.org/document/6992975/,,2014-07,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,305-308,,,,,,,,,,,IEEE,"Kanyakumari District, India",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2014 International Conference on Control, Instrumentation, Communication and Computational Technologies (ICCICCT)",,,,,,,,,,,,,,, R3IZBI46,journalArticle,2018,,"Optimization-Based Image Reconstruction From Low-Count, List-Mode TOF-PET Data",IEEE Transactions on Biomedical Engineering,,"0018-9294, 1558-2531",10.1109/TBME.2018.2802947,https://ieeexplore.ieee.org/document/8283616/,,2018-04,21/11/2018 11:54,14/04/2020 08:35,21/11/2018 11:54,936-946,,4,65,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9S6E3X58,journalArticle,2016,"Khamis, Hanan; Shimoni, Sara; Hagendorff, Andreas; Smirin, Nahum; Friedman, Zvi; Adam, Dan",Optimization-Based Speckle Tracking Algorithm for Left Ventricle Strain Estimation: A Feasibility Study,"IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control",,0885-3010,10.1109/TUFFC.2016.2569619,http://ieeexplore.ieee.org/document/7470478/,,2016-08,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,1093-1106,,8,63,,,Optimization-Based Speckle Tracking Algorithm for Left Ventricle Strain Estimation,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QDRY2E4X,conferencePaper,2013,"Mayorga, P.; Druzgalski, C.; Zeljkovic, V.; Gonzalez, O. H.",Optimized verification of respiratory sounds characteristics utilizing quantile vectors,2013 Pan American Health Care Exchanges (PAHCE),978-1-4673-6257-3 978-1-4673-6254-2 978-1-4673-6256-6,,10.1109/PAHCE.2013.6568217,http://ieeexplore.ieee.org/document/6568217/,,2013-04,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,01-May,,,,,,,,,,,IEEE,"Medellin, Colombia",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2013 Pan American Health Care Exchanges (PAHCE),,,,,,,,,,,,,,, FRXBYV86,conferencePaper,2015,"Jalo, Salihu A.; Ishak, Asnor J.; Soh, Azura Che; Rahman, Ribhan Zafira Abdul; Shamsuddin, Rosnah",Optimizing effect of frying cycles on cooking oil properties using particle swarm optimization,2015 10th Asian Control Conference (ASCC),978-1-4799-7862-5,,10.1109/ASCC.2015.7244709,http://ieeexplore.ieee.org/document/7244709/,,2015-05,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,01-May,,,,,,,,,,,IEEE,Kota Kinabalu,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 10th Asian Control Conference (ASCC),,,,,,,,,,,,,,, 9SAUYH7W,conferencePaper,2011,"Simonic, Klaus; Holzinger, Andreas; Bloice, Marcus; Hermann, Josef",Optimizing Long-Term Treatment of Rheumatoid Arthritis with Systematic Documentation,Proceedings of the 5th International ICST Conference on Pervasive Computing Technologies for Healthcare,978-1-936968-15-2,,10.4108/icst.pervasivehealth.2011.246087,http://eudl.eu/doi/10.4108/icst.pervasivehealth.2011.246087,,2011,21/11/2018 11:54,14/04/2020 08:35,21/11/2018 11:54,,,,,,,,,,,,IEEE,"Dublin, Republic of Ireland",en,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,5th International ICST Conference on Pervasive Computing Technologies for Healthcare,,,,,,,,,,,,,,, PYJJUFBU,journalArticle,2012,"Ching-Seh Wu; Khoury, I.; Shah, H.",Optimizing Medical Data Quality Based on Multiagent Web Service Framework,IEEE Transactions on Information Technology in Biomedicine,,"1089-7771, 1558-0032",10.1109/TITB.2012.2195498,http://ieeexplore.ieee.org/document/6200870/,"One of the most important issues in e-healthcare information systems is to optimize the medical data quality extracted from distributed and heterogeneous environments, which can extremely improve diagnostic and treatment decision making. This paper proposes a multiagent web service framework based on service-oriented architecture for the optimization of medical data quality in the e-healthcare information system. Based on the design of the multiagent web service framework, an evolutionary algorithm (EA) for the dynamic optimization of the medical data quality is proposed. The framework consists of two main components; first, an EA will be used to dynamically optimize the composition of medical processes into optimal task sequence according to specific quality attributes. Second, a multiagent framework will be proposed to discover, monitor, and report any inconstancy between the optimized task sequence and the actual medical records. To demonstrate the proposed framework, experimental results for a breast cancer case study are provided. Furthermore, to show the unique performance of our algorithm, a comparison with other works in the literature review will be presented.",2012-07,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,745-757,,4,16,,,,,,,,,,,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YKFJPKET,conferencePaper,2016,"Szabo, Zsolt",Options of micro-simulation in the modelling of the pension system and the intelligent IT security system,2016 IEEE 17th International Symposium on Computational Intelligence and Informatics (CINTI),978-1-5090-3909-8,,10.1109/CINTI.2016.7846421,http://ieeexplore.ieee.org/document/7846421/,,2016-11,21/11/2018 11:54,14/04/2020 08:35,21/11/2018 11:54,000295-000298,,,,,,,,,,,IEEE,"Budapest, Hungary",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 IEEE 17th International Symposium on Computational Intelligence and Informatics (CINTI),,,,,,,,,,,,,,, EM7U3RV6,conferencePaper,2014,"Orozco, Oscar Arley; Llano Ramirez, Gonzalo",OSA: A VANET application focused in energy efficiency,2014 IEEE Colombian Conference on Communications and Computing (COLCOM),978-1-4799-4340-1 978-1-4799-4342-5,,10.1109/ColComCon.2014.6860398,http://ieeexplore.ieee.org/document/6860398/,,2014-06,21/11/2018 11:54,14/04/2020 08:35,21/11/2018 11:54,01-Sep,,,,,,OSA,,,,,IEEE,"Bogota, Colombia",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2014 IEEE Colombian Conference on Communications and Computing (COLCOM),,,,,,,,,,,,,,, 7RQWMDSP,conferencePaper,2017,"Ben Amor, Lamia; Lahyani, Imene; Jmaiel, Mohamed",PCA-based multivariate anomaly detection in mobile healthcare applications,2017 IEEE/ACM 21st International Symposium on Distributed Simulation and Real Time Applications (DS-RT),978-1-5386-4028-9,,10.1109/DISTRA.2017.8167682,http://ieeexplore.ieee.org/document/8167682/,,2017-10,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,01-Aug,,,,,,,,,,,IEEE,Rome,,,,,,Crossref,,,,,,anomaly detection; mhealth; multivariate; principal component analysis; robustness; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 IEEE/ACM 21st International Symposium on Distributed Simulation and Real-Time Applications (DS-RT),,,,,,,,,,,,,,, 59TEHIWT,journalArticle,2014,"Davidson Ward, Sally L.; Amin, Raouf; Arens, Raanan; Chen, Zhongping; Davis, Stephanie; Gutmark, Ephraim; Superfine, Richard; Wong, Brian; Zdanski, Carlton; Khoo, Michael C.K.",Pediatric Sleep-Related Breathing Disorders: Advances in imaging and computational modeling.,IEEE Pulse,,2154-2287,10.1109/MPUL.2014.2339293,http://ieeexplore.ieee.org/document/6908145/,,2014-09,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,33-39,,5,5,,,Pediatric Sleep-Related Breathing Disorders,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8VVD6BXL,conferencePaper,2004,"Goodenow, T.; Karchnak, M.; Shipman, R.",Performance comparison of robust laser interferometer (RLI) and contact accelerometer technology in aviation health monitoring,2004 IEEE Aerospace Conference Proceedings (IEEE Cat. No.04TH8720),978-0-7803-8155-1,,10.1109/AERO.2004.1368183,http://ieeexplore.ieee.org/document/1368183/,,2004,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,3663-3685,,,6,,,,,,,,IEEE,"Big Sky, MT, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2004 IEEE Aerospace Conference Proceedings (IEEE Cat. No.04TH8720),,,,,,,,,,,,,,, VCBD5KWJ,conferencePaper,2009,"Fernandez-Lopez, Helena; Macedo, Pedro; Afonso, Jose A.; Correia, J. H.; Simoes, Ricardo",Performance evaluation of a ZigBee-based medical sensor network,Proceedings of the 3d International ICST Conference on Pervasive Computing Technologies for Healthcare,,,10.4108/ICST.PERVASIVEHEALTH2009.6002,http://eudl.eu/doi/10.4108/ICST.PERVASIVEHEALTH2009.6002,,2009,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,,,,,,,,,,,,ICST,"London, UK",en,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,3d International ICST Conference on Pervasive Computing Technologies for Healthcare,,,,,,,,,,,,,,, 2Y2HD4E9,conferencePaper,2018,"Kouka, Neji; Guesmi, Tarek; Korbaa, Ouajdi",Performance Evaluation of IEEE 802.15.6 Channel Access Procedure in WBAN,2018 IEEE 6th International Conference on Future Internet of Things and Cloud (FiCloud),978-1-5386-7503-8,,10.1109/FiCloud.2018.00031,https://ieeexplore.ieee.org/document/8458008/,,2018-08,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,162-168,,,,,,,,,,,IEEE,Barcelona,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2018 IEEE 6th International Conference on Future Internet of Things and Cloud (FiCloud),,,,,,,,,,,,,,, L5ASJB3Z,conferencePaper,2016,"Alamsyah; Purnomo, Mauridhi Hery; Purnama, I Ketut Edy; Setijadi, Eko","Performance of the routing protocols AODV, DSDV and OLSR in health monitoring using NS3",2016 International Seminar on Intelligent Technology and Its Applications (ISITIA),978-1-5090-1709-6,,10.1109/ISITIA.2016.7828680,http://ieeexplore.ieee.org/document/7828680/,,2016-07,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,323-328,,,,,,,,,,,IEEE,"Lombok, Indonesia",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 International Seminar on Intelligent Technology and Its Applications (ISITIA),,,,,,,,,,,,,,, HQV4T4P3,conferencePaper,2014,"Zhang, Qi; Chaturvedi, Manila; Jacobsen, Rune Hylsberg",Performance study of the enhancement schemes for Baseline MAC of Body Area networks,2014 8th International Symposium on Medical Information and Communication Technology (ISMICT),978-1-4799-4856-7,,10.1109/ISMICT.2014.6825223,http://ieeexplore.ieee.org/document/6825223/,,2014-04,21/11/2018 11:54,14/04/2020 08:35,21/11/2018 11:54,01-May,,,,,,,,,,,IEEE,"Firenze, Italy",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2014 8th International Symposium on Medical Information and Communication Technology (ISMICT),,,,,,,,,,,,,,, FYLGZQCV,conferencePaper,2011,"Bardram, Jakob E.; Doryab, Afsaneh; Jensen, Rune M.; Lange, Poul M.; Nielsen, Kristian L. G.; Petersen, Soren T.",Phase recognition during surgical procedures using embedded and body-worn sensors,2011 IEEE International Conference on Pervasive Computing and Communications (PerCom),978-1-4244-9530-6,,10.1109/PERCOM.2011.5767594,http://ieeexplore.ieee.org/document/5767594/,,2011-03,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,45-53,,,,,,,,,,,IEEE,"Seattle, WA, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2011 IEEE International Conference on Pervasive Computing and Communications (PerCom),,,,,,,,,,,,,,, QALXMFA5,conferencePaper,2018,"Fadheel, Wesam; Salih, Raed; Lilien, Leszek",PHeDHA: Protecting Healthcare Data in Health Information Exchanges with Active Data Bundles,"2018 17th IEEE International Conference On Trust, Security And Privacy In Computing And Communications/ 12th IEEE International Conference On Big Data Science And Engineering (TrustCom/BigDataSE)",978-1-5386-4388-4,,10.1109/TrustCom/BigDataSE.2018.00164,https://ieeexplore.ieee.org/document/8456033/,,2018-08,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,1187-1195,,,,,,PHeDHA,,,,,IEEE,"New York, NY, USA",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2018 17th IEEE International Conference On Trust, Security And Privacy In Computing And Communications/ 12th IEEE International Conference On Big Data Science And Engineering (TrustCom/BigDataSE)",,,,,,,,,,,,,,, RRRSYVI2,journalArticle,2015,"Xu, Jiuping; Wang, Yusheng; Xu, Lei",PHM-Oriented Sensor Optimization Selection Based on Multiobjective Model for Aircraft Engines,IEEE Sensors Journal,,"1530-437X, 1558-1748",10.1109/JSEN.2015.2430361,http://ieeexplore.ieee.org/document/7102712/,,2015-09,21/11/2018 11:54,14/04/2020 08:35,21/11/2018 11:54,4836-4844,,9,15,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NL5V8CKE,conferencePaper,2017,"Hosseini, Mohammad; Berlin, Richard B.; Sha, Lui",Physiology-Aware Rural Ambulance Routing,2017 IEEE International Conference on Healthcare Informatics (ICHI),978-1-5090-4881-6,,10.1109/ICHI.2017.27,http://ieeexplore.ieee.org/document/8031170/,,2017-08,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,332-337,,,,,,,,,,,IEEE,"Park City, UT, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 IEEE International Conference on Healthcare Informatics (ICHI),,,,,,,,,,,,,,, HSJ6RC7A,conferencePaper,2009,"Hussein, Sherif E.",Picture Archiving and Communication System Analysis and Deployment,2009 11th International Conference on Computer Modelling and Simulation,978-1-4244-3771-9 978-0-7695-3593-7,,10.1109/UKSIM.2009.36,http://ieeexplore.ieee.org/lpdocs/epic03/wrapper.htm?arnumber=4809818,,2009,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,520-525,,,,,,,,,,,IEEE,"Cambridge, UK",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2009 11th International Conference on Computer Modelling and Simulation,,,,,,,,,,,,,,, A7XGSGJ9,conferencePaper,2010,"Carr, Sean; Roberts, Stephen","Planning for infectious disease outbreaks: A geographic disease spread, clinic location, and resource allocation simulation",Proceedings of the 2010 Winter Simulation Conference,978-1-4244-9866-6,,10.1109/WSC.2010.5678858,http://ieeexplore.ieee.org/document/5678858/,,2010-12,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,2171-2184,,,,,,Planning for infectious disease outbreaks,,,,,IEEE,"Baltimore, MD, USA",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2010 Winter Simulation Conference - (WSC 2010),,,,,,,,,,,,,,, HXLYEA3R,conferencePaper,2017,"Gupta, Rajni; Pradhan, Gitanjali; Biswas, Suparna",Polling vs no polling: QoS driven performance analysis of IEEE 802.15.6 for varying data rate in WBAN,2017 IEEE International Conference on Advanced Networks and Telecommunications Systems (ANTS),978-1-5386-2347-3,,10.1109/ANTS.2017.8384135,https://ieeexplore.ieee.org/document/8384135/,,2017-12,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,01-Jun,,,,,,Polling vs no polling,,,,,IEEE,Bhubaneswar,,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 IEEE International Conference on Advanced Networks and Telecommunications Systems (ANTS),,,,,,,,,,,,,,, E7AZVTRD,conferencePaper,2018,"Helmy, Amir; Helmy, Ahmed",Poster abstract: Detecting epileptic seizures with a smartphone using frequency analysis,IEEE INFOCOM 2018 - IEEE Conference on Computer Communications Workshops (INFOCOM WKSHPS),978-1-5386-5979-3,,10.1109/INFCOMW.2018.8406999,https://ieeexplore.ieee.org/document/8406999/,,2018-04,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,01-Feb,,,,,,Poster abstract,,,,,IEEE,"Honolulu, HI, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEEE INFOCOM 2018 - IEEE Conference on Computer Communications Workshops (INFOCOM WKSHPS),,,,,,,,,,,,,,, J394V5PS,conferencePaper,2015,"Kherani, Arzad Alam; Chiddarwar, Anand Sudhakar; Singh, Ajeet Kumar",Power and QoS optimization for BLE-based Accessory-Smartphone communications,2015 12th Annual IEEE Consumer Communications and Networking Conference (CCNC),978-1-4799-6390-4,,10.1109/CCNC.2015.7158008,http://ieeexplore.ieee.org/document/7158008/,,2015-01,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,394-399,,,,,,,,,,,IEEE,"Las Vegas, NV, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 12th Annual IEEE Consumer Communications and Networking Conference (CCNC),,,,,,,,,,,,,,, LW6BL2SR,journalArticle,2014,"Thotahewa, Kasun M. S.; Khan, Jamil Y.; Yuce, Mehmet R.",Power Efficient Ultra Wide Band Based Wireless Body Area Networks with Narrowband Feedback Path,IEEE Transactions on Mobile Computing,,1536-1233,10.1109/TMC.2013.120,http://ieeexplore.ieee.org/document/6594741/,,2014-08,21/11/2018 11:54,14/04/2020 08:35,21/11/2018 11:54,1829-1842,,8,13,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MABJ6YPJ,conferencePaper,2011,"Daloub, L. M.",Power quality optimization and reactive power control by modeling of SVC in healthcare centre,11th International Conference on Electrical Power Quality and Utilisation,978-1-4673-0378-1 978-1-4673-0379-8,,10.1109/EPQU.2011.6128906,http://ieeexplore.ieee.org/document/6128906/,,2011-10,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,01-May,,,,,,,,,,,IEEE,"Lisbon, Portugal",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2011 11th International Conference on Electrical Power Quality and Utilisation - (EPQU),,,,,,,,,,,,,,, 7HE7SQNW,conferencePaper,2017,"Yekkala, Indu; Dixit, Sunanda; Jabbar, M. A.",Prediction of heart disease using ensemble learning and Particle Swarm Optimization,2017 International Conference On Smart Technologies For Smart Nation (SmartTechCon),978-1-5386-0569-1,,10.1109/SmartTechCon.2017.8358460,https://ieeexplore.ieee.org/document/8358460/,,2017-08,21/11/2018 11:54,14/04/2020 08:35,21/11/2018 11:54,691-698,,,,,,,,,,,IEEE,Bangalore,,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 International Conference On Smart Technologies For Smart Nation (SmartTechCon),,,,,,,,,,,,,,, HWXJCIFJ,conferencePaper,2017,"Felmeister, Alex S.; Waanders, Angela J.; Leary, Sarah E. S.; Stevens, Jeff; Mason, Jennifer L.; Teneralli, Rachel; Hu, Xiaohua; Bailey, L. Charles",Preliminary exploratory data analysis of simulated national clinical data research network for future use in annotation of a rare tumor biobanking initiative,2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM),978-1-5090-3050-7,,10.1109/BIBM.2017.8217983,http://ieeexplore.ieee.org/document/8217983/,,2017-11,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,2098-2104,,,,,,,,,,,IEEE,"Kansas City, MO",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM),,,,,,,,,,,,,,, DTGNSUN8,conferencePaper,2014,"Bian, Junguo; Sharp, Gregory C.; Park, Yang-kyun; Bortfeld, Thomas; El Fakhri, Georges",Preliminary investigation of CBCT imaging optimization for Image-guided radiation therapy,2014 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC),978-1-4799-6097-2,,10.1109/NSSMIC.2014.7430871,http://ieeexplore.ieee.org/document/7430871/,,2014-11,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,01-Apr,,,,,,,,,,,IEEE,"Seattle, WA, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2014 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC),,,,,,,,,,,,,,, 72IM58JR,journalArticle,2016,"Jaimes, Luis G.; Llofriu, Martin; Raij, Andrew","PREVENTER, a Selection Mechanism for Just-in-Time Preventive Interventions",IEEE Transactions on Affective Computing,,1949-3045,10.1109/TAFFC.2015.2490062,http://ieeexplore.ieee.org/document/7296599/,,01/07/2016,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,243-257,,3,7,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GQW2D9XF,conferencePaper,2009,"Taylor, Bruce; Hipel, Lloyd; Hipel, Keith W.; Liping Fang; Heng, Michele",Preventing future brownfields engineering solutions and pollution prevention policies,2009 IEEE Toronto International Conference Science and Technology for Humanity (TIC-STH),978-1-4244-3877-8,,10.1109/TIC-STH.2009.5444530,http://ieeexplore.ieee.org/document/5444530/,,2009-09,21/11/2018 11:54,14/04/2020 08:35,21/11/2018 11:54,1030-1035,,,,,,,,,,,IEEE,"Toronto, ON, Canada",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2009 IEEE Toronto International Conference - Science and Technology for Humanity (TIC-STH 2009),,,,,,,,,,,,,,, 8PATEJVX,conferencePaper,2014,"Aral, Karca D.; Chick, Stephen E.; Grabosch, Alfons",Primary preventive care model for Type 2 Diabetes: Input calibration with response data,Proceedings of the Winter Simulation Conference 2014,978-1-4799-7486-3 978-1-4799-7484-9,,10.1109/WSC.2014.7019994,http://ieeexplore.ieee.org/document/7019994/,"Type 2 Diabetes Mellitus (T2DM) and its complications account for 11% of the global health expenditure (IDF 2012). Different primary, secondary, and tertiary preventive interventions promise better health outcomes and cost savings but are often studied separately. This paper proposes a simulation model for T2DM that comprehends the nonlinear interactions of multiple interventions for various stages of T2DM on population dynamics, health outcomes, and costs. We summarize the model, then demonstrate how we addressed the important challenge of fitting input parameters given that data needed to be combined from disparate sources of data sources in a way that calibrates input parameters to output metrics over a range of decision variables (a form of model calibration to achieve a response model match to clinical data). We present preliminary numerical results to inform policies for T2DM prevention and management.",2014-12,21/11/2018 11:54,14/04/2020 08:34,21/11/2018 11:54,1399-1410,,,,,,Primary preventive care model for Type 2 Diabetes,,,,,IEEE,"Savanah, GA, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2014 Winter Simulation Conference - (WSC 2014),,,,,,,,,,,,,,, R3TJDDGG,conferencePaper,2011,"Nasri, M; Helali, A; Sghaier, H; Maaref, H",Priority image transmission in wireless sensor networks,"Eighth International Multi-Conference on Systems, Signals & Devices",978-1-4577-0413-0,,10.1109/SSD.2011.5767468,http://ieeexplore.ieee.org/document/5767468/,,2011-03,21/11/2018 11:54,14/04/2020 08:35,21/11/2018 11:54,01-Jun,,,,,,,,,,,IEEE,Sousse,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2011 8th International Multi-Conference on Systems, Signals and Devices (SSD 2011)",,,,,,,,,,,,,,, SBDRI23H,conferencePaper,2017,"Sivaramasastry, Adishesha; Das, Subhra Kanti; Mazumdar, Chandan; Banerjee, Kumardeb; Barik, Mridul Sankar",Priority queuing model for analysis of network traffic in flight operations of commercial aircraft,"2017 International Conference on Circuits, Controls, and Communications (CCUBE)",978-1-5386-0615-5,,10.1109/CCUBE.2017.8394172,https://ieeexplore.ieee.org/document/8394172/,,2017-12,21/11/2018 11:55,14/04/2020 08:35,21/11/2018 11:55,25-30,,,,,,,,,,,IEEE,Bangalore,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2017 International Conference on Circuits, Controls, and Communications (CCUBE)",,,,,,,,,,,,,,, PVGL52WF,conferencePaper,2017,"Vahdat, Vahab; Griffin, Jacqueline; Burns, Sarah; Azghandi, Rana",Proactive patient flow redesign for integration of multiple outpatient clinics,2017 Winter Simulation Conference (WSC),978-1-5386-3428-8,,10.1109/WSC.2017.8248012,http://ieeexplore.ieee.org/document/8248012/,"Successful merging or consolidation of interdependent healthcare clinics have been shown to have benefits with regards to decreasing operation costs while maintaining patients' quality of care. In order to achieve a successful merger or integration of clinics, an analysis of the effects of integrating patient flows should occur. This is especially important when the merger of clinics involves a transition into a new facility. We utilize a discrete event simulation model to study the effects of integrating three interdependent musculoskeletal clinics, Orthopedics, Rheumatology, and Radiology, into a new facility in advance of implementation. Through use of the simulation, unexpected bottlenecks in the check-in process are identified and the effects of implementing new patient flows, supported by Real-Time Location System (RTLS) technology, are analyzed",2017-12,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,2893-2904,,,,,,,,,,,IEEE,"Las Vegas, NV",,,,,,Crossref,,,,,,00; Review,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 Winter Simulation Conference (WSC),,,,,,,,,,,,,,, DCPKFJD7,journalArticle,2015,"Neumann, Dominik; Grbic, Sasa; John, Matthias; Navab, Nassir; Hornegger, Joachim; Ionasec, Razvan",Probabilistic Sparse Matching for Robust 3D/3D Fusion in Minimally Invasive Surgery,IEEE Transactions on Medical Imaging,,"0278-0062, 1558-254X",10.1109/TMI.2014.2343936,http://ieeexplore.ieee.org/lpdocs/epic03/wrapper.htm?arnumber=6867344,,2015-01,21/11/2018 11:55,14/04/2020 08:35,21/11/2018 11:55,49-60,,1,34,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VQU7KSRI,conferencePaper,2014,"Moschonas, Panagiotis; Tsakiris, Athanasios; Tzovaras, Dimitrios",Product accessibility evaluation using virtual user models,2014 IEEE Virtual Reality (VR),978-1-4799-2871-2,,10.1109/VR.2014.6802110,http://ieeexplore.ieee.org/document/6802110/,,2014-03,21/11/2018 11:55,14/04/2020 08:35,21/11/2018 11:55,179-180,,,,,,,,,,,IEEE,"Minneapolis, MN, USA",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2014 IEEE Virtual Reality (VR),,,,,,,,,,,,,,, FSZ7MSAE,conferencePaper,2014,"Agapito, Giuseppe; Calabrese, Barbara; Care, Ilaria; Falcone, Daniela; Guzzi, Pietro Hiram; Ielpo, Nicola; Lamprinoudi, Theodora; Milano, Marianna; Simeoni, Mariadelina; Cannataro, Mario",Profiling basic health information of tourists: towards a recommendation system for the adaptive delivery of medical certified nutrition contents,2014 International Conference on High Performance Computing & Simulation (HPCS),978-1-4799-5313-4 978-1-4799-5312-7 978-1-4799-5311-0,,10.1109/HPCSim.2014.6903744,http://ieeexplore.ieee.org/document/6903744/,"In this paper, we propose a recommendation system for the adaptive delivery of nutrition contents both to healthy and chronically ill tourists in order to improve their quality of life by combining the needs of leisure with health benefits. The proposed system provides individualized nutritional recommendation according to the health user profile. The profile is created through the supply of dynamic real time questionnaire to the user. The system is able to suggest not only the use of specific typical foods, but also it gives dietary indications related to some specific pathologies or health conditions.",2014-07,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,616-620,,,,,,Profiling basic health information of tourists,,,,,IEEE,"Bologna, Italy",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2014 International Conference on High Performance Computing & Simulation (HPCS),,,,,,,,,,,,,,, J5GPBY2N,journalArticle,2014,"Soualhi, Abdenour; Razik, Hubert; Clerc, Guy; Doan, Dinh Dong",Prognosis of Bearing Failures Using Hidden Markov Models and the Adaptive Neuro-Fuzzy Inference System,IEEE Transactions on Industrial Electronics,,"0278-0046, 1557-9948",10.1109/TIE.2013.2274415,http://ieeexplore.ieee.org/document/6566058/,,2014-06,21/11/2018 11:55,14/04/2020 08:35,21/11/2018 11:55,2864-2874,,6,61,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QLI4QSMP,conferencePaper,2012,"He, Zhaomin; Wang, Shaoping; Wang, Kang; Li, Kai",Prognostic analysis based on hybrid prediction method for axial piston pump,IEEE 10th International Conference on Industrial Informatics,978-1-4673-0311-8 978-1-4673-0312-5 978-1-4673-0310-1,,10.1109/INDIN.2012.6301185,http://ieeexplore.ieee.org/document/6301185/,,2012-07,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,688-692,,,,,,,,,,,IEEE,"Beijing, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 10th IEEE International Conference on Industrial Informatics (INDIN),,,,,,,,,,,,,,, VFIQ4G9M,conferencePaper,2018,"Gogu, Christian",Prognostics and health management: Current state-of-the-art for optimizing aircraft structural maintenance,"2018 19th International Conference on Thermal, Mechanical and Multi-Physics Simulation and Experiments in Microelectronics and Microsystems (EuroSimE)",978-1-5386-2359-6,,10.1109/EuroSimE.2018.8369957,https://ieeexplore.ieee.org/document/8369957/,,2018-04,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,01-Apr,,,,,,Prognostics and health management,,,,,IEEE,Toulouse,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2018 19th International Conference on Thermal, Mechanical and Multi-Physics Simulation and Experiments in Microelectronics and Microsystems (EuroSimE)",,,,,,,,,,,,,,, XCAXAQGD,conferencePaper,2015,"Khan, Faisal; Eker, Omer. F.; Jennions, Ian K.; Tsourdos, Antonios",Prognostics of crack propagation in structures using time delay neural network,2015 IEEE Conference on Prognostics and Health Management (PHM),978-1-4799-1894-2,,10.1109/ICPHM.2015.7245040,http://ieeexplore.ieee.org/document/7245040/,,2015-06,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,01-Jun,,,,,,,,,,,IEEE,"Austin, TX, USA",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 IEEE Conference on Prognostics and Health Management (PHM),,,,,,,,,,,,,,, 2JZNLM78,conferencePaper,2015,"Vidyanti, Irene; Basurto-Davila, Ricardo",Projecting long-term impact of modest sodium reduction in Los Angeles County,2015 Winter Simulation Conference (WSC),978-1-4673-9743-8,,10.1109/WSC.2015.7408268,http://ieeexplore.ieee.org/document/7408268/,"Heart attacks and strokes are the leading causes of death in Los Angeles County (LAC). Dietary sodium reduction policies may reduce the risk for heart disease and stroke. To determine the value of population-level sodium reduction policies in LAC in terms of averted morbidity, mortality, and total medical spending, we modeled a modest sodium consumption reduction scenario of 400 mg/day using the Future Elderly Model-Los Angeles (FEM-LA), a Monte Carlo microsimulation model that projects health and economic outcomes for all LAC residents aged 51 and older. The model projects that, over the period 2006-2051, 3,224-5,353 total deaths (annual average of 70-116 deaths) would be prevented due to reductions in the incidence of heart disease and stroke attributed to dietary salt reduction. Over the same period, this corresponds to a total savings of 2.28−3.56billioninmedicalspending(annualaverageof49.56-77.37 million).",2015-12,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,1459-1470,,,,,,,,,,,IEEE,"Huntington Beach, CA, USA",,,,,,Crossref,,,,,,00; Review,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 Winter Simulation Conference (WSC),,,,,,,,,,,,,,, 3Z4QRSGI,journalArticle,2012,"Grundfest, W. S.; Lai, E.; Peterson, C. M.; Friedl, K. E.",Promoting Innovation and Convergence in Military Medicine: Technology-Inspired Problem Solving,IEEE Circuits and Systems Magazine,,1531-636X,10.1109/MCAS.2012.2205974,http://ieeexplore.ieee.org/document/6279616/,,2012,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,14-29,,3,12,,,Promoting Innovation and Convergence in Military Medicine,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LI5G53UI,conferencePaper,2014,"Mason-Blakley, Fieran; Habibi, Ryan",Prospective Hazard Analysis for Information System,2014 IEEE International Conference on Healthcare Informatics,978-1-4799-5701-9,,10.1109/ICHI.2014.43,http://ieeexplore.ieee.org/document/7052498/,,2014-09,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,256-265,,,,,,,,,,,IEEE,"Verona, Italy",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2014 IEEE International Conference on Healthcare Informatics (ICHI),,,,,,,,,,,,,,, KYUDEKU4,journalArticle,2010,"Hsin-Min Lu; Zeng, D.; HsinChun Chen",Prospective Infectious Disease Outbreak Detection Using Markov Switching Models,IEEE Transactions on Knowledge and Data Engineering,,1041-4347,10.1109/TKDE.2009.115,http://ieeexplore.ieee.org/document/4912199/,,2010-04,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,565-577,,4,22,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 46XX5IQA,conferencePaper,2006,"Chigan, C.; Oberoi, V.",Providing QoS in Ubiquitous Telemedicine Networks,Fourth Annual IEEE International Conference on Pervasive Computing and Communications Workshops (PERCOMW'06),978-0-7695-2520-4,,10.1109/PERCOMW.2006.112,http://ieeexplore.ieee.org/document/1599034/,,2006,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,496-500,,,,,,,,,,,IEEE,"Pisa, Italy",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Fourth Annual IEEE International Conference on Pervasive Computing and Communications Workshops (PERCOMW'06),,,,,,,,,,,,,,, G5EGCXMQ,conferencePaper,2007,"Abe, N.; Mizokami, R.; Kinoshita, Y.; He, S.",Providing Simulation of Medical Manipulation with Haptic Feedback,17th International Conference on Artificial Reality and Telexistence (ICAT 2007),978-0-7695-3056-7,,10.1109/ICAT.2007.14,http://ieeexplore.ieee.org/document/4414627/,,2007-11,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,143-148,,,,,,,,,,,IEEE,Denmark,,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,17th International Conference on Artificial Reality and Telexistence (ICAT 2007),,,,,,,,,,,,,,, I92WI4WR,conferencePaper,2011,"Swiatek, Pawel; Drwal, Maciej; Grzech, Adam",Providing Strict QoS Guaranties for Flows with Time-varying Capacity Requirements,2011 21st International Conference on Systems Engineering,978-1-4577-1078-0,,10.1109/ICSEng.2011.57,http://ieeexplore.ieee.org/document/6041846/,,2011-08,21/11/2018 11:55,14/04/2020 08:35,21/11/2018 11:55,279-284,,,,,,,,,,,IEEE,"Las Vegas, NV, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2011 21st International Conference on Systems Engineering (ICSEng),,,,,,,,,,,,,,, MZ6MWMH9,conferencePaper,2006,"Zhang, Yansheng; Fu, Jicheng; Yen, I-ling; Bastani, Farokh; Tai, Ann; Chau, Savio; Vatan, Farrokh; Fijany, Amir",QoS Adaptive ISHM Systems,2006 18th IEEE International Conference on Tools with Artificial Intelligence (ICTAI'06),978-0-7695-2728-4,,10.1109/ICTAI.2006.99,http://ieeexplore.ieee.org/document/4031879/,,2006-11,21/11/2018 11:55,14/04/2020 08:35,21/11/2018 11:55,47-54,,,,,,,,,,,IEEE,"Arlington, VA, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2006 18th IEEE International Conference on Tools with Artificial Intelligence (ICTAI'06),,,,,,,,,,,,,,, JV5S3B3F,conferencePaper,2015,"Bradai, Nourchene; Ben Elhadj, Hadda; Boudjit, Saadi; Chaari, Lamia; Kamoun, Lotfi",QoS architecture over WBANs for remote vital signs monitoring applications,2015 12th Annual IEEE Consumer Communications and Networking Conference (CCNC),978-1-4799-6390-4,,10.1109/CCNC.2015.7157937,http://ieeexplore.ieee.org/document/7157937/,,2015-01,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,01-Jun,,,,,,,,,,,IEEE,"Las Vegas, NV, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 12th Annual IEEE Consumer Communications and Networking Conference (CCNC),,,,,,,,,,,,,,, 7MLE2KVR,conferencePaper,2010,"Ali, Khaled A.; Sarker, Jahangir H.; Mouftah, Hussein T.",QoS-based MAC protocol for medical wireless body area sensor networks,The IEEE symposium on Computers and Communications,978-1-4244-7754-8,,10.1109/ISCC.2010.5546523,http://ieeexplore.ieee.org/document/5546523/,,2010-06,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,216-221,,,,,,,,,,,IEEE,"Riccione, Italy",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2010 IEEE Symposium on Computers and Communications (ISCC),,,,,,,,,,,,,,, YEWB6MZM,conferencePaper,2015,"Zhao, Xiaosong; Liu, Bin; Chen, Chang; Chen, Chang Wen",QoS-Driven Power Control for Inter-WBAN Interference Mitigation,2015 IEEE Global Communications Conference (GLOBECOM),978-1-4799-5952-5,,10.1109/GLOCOM.2015.7417058,http://ieeexplore.ieee.org/document/7417058/,,2015-12,21/11/2018 11:55,14/04/2020 08:35,21/11/2018 11:55,01-Jun,,,,,,,,,,,IEEE,"San Diego, CA, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GLOBECOM 2015 - 2015 IEEE Global Communications Conference,,,,,,,,,,,,,,, 5WQ5RJ4Y,conferencePaper,2012,"Yan, Zhisheng; Liu, Bin; Chen, Chang Wen",QoS-driven scheduling approach using optimal slot allocation for Wireless Body Area Networks,"2012 IEEE 14th International Conference on e-Health Networking, Applications and Services (Healthcom)",978-1-4577-2040-6 978-1-4577-2039-0 978-1-4577-2038-3,,10.1109/HealthCom.2012.6379419,http://ieeexplore.ieee.org/document/6379419/,,2012-10,21/11/2018 11:55,14/04/2020 08:35,21/11/2018 11:55,267-272,,,,,,,,,,,IEEE,"Beijing, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2012 IEEE 14th International Conference on e-Health Networking, Applications and Services (Healthcom 2012)",,,,,,,,,,,,,,, 4ZHUZ9MC,conferencePaper,2014,"Lanzarone, Ettore; Masclet, Cedric; Noel, Frederic",Qualitative assessment of a collaborative multi-user tool for enhancing the daily replanning and control of visits in Home Care services,2014 5th IEEE Conference on Cognitive Infocommunications (CogInfoCom),978-1-4799-7280-7,,10.1109/CogInfoCom.2014.7020459,http://ieeexplore.ieee.org/document/7020459/,,2014-11,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,267-272,,,,,,,,,,,IEEE,"Vietri sul Mare, Italy",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2014 5th IEEE Conference on Cognitive Infocommunications (CogInfoCom),,,,,,,,,,,,,,, LMHIHU4R,conferencePaper,2017,"Nazario, Debora Cabral; Campos, Pedro J.; Inacio, Eduardo C.; Dantas, Mario A. R.",Quality of Context Evaluating Approach in AAL Environment Using IoT Technology,2017 IEEE 30th International Symposium on Computer-Based Medical Systems (CBMS),978-1-5386-1710-6,,10.1109/CBMS.2017.55,http://ieeexplore.ieee.org/document/8104257/,,2017-06,21/11/2018 11:55,14/04/2020 08:35,21/11/2018 11:55,558-563,,,,,,,,,,,IEEE,Thessaloniki,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 IEEE 30th International Symposium on Computer-Based Medical Systems (CBMS),,,,,,,,,,,,,,, 43XQHQ2Z,conferencePaper,2011,"Leong, Pei Fung; Labadin, Jane; Rahman, Shapiee Bin Abd; Juan, Sarah Flora Samson",Quantifying the relationship between the climate and Hand-Foot-Mouth Disease (HFMD) incidences,"2011 Fourth International Conference on Modeling, Simulation and Applied Optimization",978-1-4577-0003-3,,10.1109/ICMSAO.2011.5775582,http://ieeexplore.ieee.org/document/5775582/,,2011-04,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,01-May,,,,,,,,,,,IEEE,"Kuala Lumpur, Malaysia",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2011 Fourth International Conference on Modeling, Simulation and Applied Optimization (ICMSAO)",,,,,,,,,,,,,,, HINAKCAT,conferencePaper,2008,"Burnley, P.",Railway law corporate manslaughter,"IET Seminar on Railway Law for Engineers: How Legislation, Liability and Legal Issues Affect You",978-0-86341-898-3,,10.1049/ic:20080600,http://digital-library.theiet.org/content/conferences/10.1049/ic_20080600,,2008,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,05-May,,,,,,,,,,,IEE,"London, UK",en,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"IET Seminar on Railway Law for Engineers: How Legislation, Liability and Legal Issues Affect You",,,,,,,,,,,,,,, JVQKL6H6,journalArticle,2013,"Torabi, N.; Leung, V. C. M.",Realization of Public M-Health Service in License-Free Spectrum,IEEE Journal of Biomedical and Health Informatics,,"2168-2194, 2168-2208",10.1109/TITB.2012.2227117,http://ieeexplore.ieee.org/document/6352913/,,2013-01,21/11/2018 11:55,14/04/2020 08:35,21/11/2018 11:55,19-29,,1,17,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4YGATGLE,conferencePaper,2011,"Yu, Ruiyun; Wu, Wanjian; Xia, Nian; Geng, Haobo; Liu, Mingyu",Real-time carbon dioxide emission monitoring system based on participatory sensing technology,The Fourth International Workshop on Advanced Computational Intelligence,978-1-61284-375-9 978-1-61284-374-2 978-1-61284-373-5,,10.1109/IWACI.2011.6160008,http://ieeexplore.ieee.org/document/6160008/,,2011-10,21/11/2018 11:55,14/04/2020 08:35,21/11/2018 11:55,230-235,,,,,,,,,,,IEEE,"Wuhan, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2011 Fourth International Workshop on Advanced Computational Intelligence (IWACI),,,,,,,,,,,,,,, 4YLUMQUC,conferencePaper,2015,"Hsu, Sonya; Benton, Ryan; Gottumukkala, Raju",Real-Time Flu Monitoring System and Decision Informatics,2015 48th Hawaii International Conference on System Sciences,978-1-4799-7367-5,,10.1109/HICSS.2015.338,http://ieeexplore.ieee.org/document/7070153/,"This paper presents a flu monitoring system that utilizes prescriptions-based data. It provides evidence-base information that may be ""useful"" to many users, e.g., Medical professionals, public health administrators, patients, prescription drugs manufacturers, elementary/middle/high schools. The system consists of a real-time flu surveillance engine and a web based client. The real-time flu surveillance engine consumes E-prescription data feeds in XML format. The analytical engine performs Extraction/Load/Transform (ETL) operations to extract prescriptions, dosage, patient information, and pharmacy location information from the prescriptions, and then, presents a relative flu risk index by zip code. The flu tracking information is published in real-time via geodatabase map application that resides on a Web portal. This flu tracking system differs from available flu tracking systems in three ways: 1) it has real-time updating capability, 2) it incorporates a prediction component, and 3) it integrates the monitoring and predicting capabilities in one system with layers of access right to different users.",2015-01,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,2794-2803,,,,,,,,,,,IEEE,"HI, USA",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 48th Hawaii International Conference on System Sciences (HICSS),,,,,,,,,,,,,,, 3J3SXHY6,conferencePaper,2014,"Awad, Alaa; Hamdy, Medhat; Mohamed, Amr; Alnuweiri, Hussein",Real-time implementation and evaluation of an adaptive energy-aware data compression for wireless EEG monitoring systems,"10th International Conference on Heterogeneous Networking for Quality, Reliability, Security and Robustness",978-1-63190-025-9,,10.1109/QSHINE.2014.6928668,http://ieeexplore.ieee.org/document/6928668/,,2014-08,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,108-114,,,,,,,,,,,IEEE,"Rhodes, Greece",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2014 10th International Conference on Heterogeneous Networking for Quality, Reliability, Security and Robustness (QShine)",,,,,,,,,,,,,,, JVKSJFRR,conferencePaper,2014,"Jalal, Ahmad; Kamal, S.",Real-time life logging via a depth silhouette-based human activity recognition system for smart home services,2014 11th IEEE International Conference on Advanced Video and Signal Based Surveillance (AVSS),978-1-4799-4871-0,,10.1109/AVSS.2014.6918647,http://ieeexplore.ieee.org/lpdocs/epic03/wrapper.htm?arnumber=6918647,,2014-08,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,74-80,,,,,,,,,,,IEEE,"Seoul, South Korea",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2014 International Conference on Advanced Video and Signal Based Surveillance (AVSS),,,,,,,,,,,,,,, Q9V7IFT9,conferencePaper,2013,"Qinghua Shen; Xiaohui Liang; Xuemin Shen; Xiaodong Lin; Luo, Henry",RECCE: A reliable and efficient cloud cooperation scheme in E-healthcare,2013 IEEE Global Communications Conference (GLOBECOM),978-1-4799-1353-4,,10.1109/GLOCOM.2013.6831488,http://ieeexplore.ieee.org/document/6831488/,,2013-12,21/11/2018 11:55,14/04/2020 08:35,21/11/2018 11:55,2736-2741,,,,,,RECCE,,,,,IEEE,"Atlanta, GA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2013 IEEE Global Communications Conference (GLOBECOM 2013),,,,,,,,,,,,,,, C2R4WA6P,conferencePaper,2012,"Bhagwan, Varun; Grandison, Tyrone; Maltzahn, Carlos",Recommendation-Based De-identification: A Practical Systems Approach towards De-identification of Unstructured Text in Healthcare,2012 IEEE Eighth World Congress on Services,978-1-4673-3053-4 978-0-7695-4756-5,,10.1109/SERVICES.2012.57,http://ieeexplore.ieee.org/document/6274045/,,2012-06,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,155-162,,,,,,Recommendation-Based De-identification,,,,,IEEE,"Honolulu, HI, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 IEEE World Congress on Services (SERVICES),,,,,,,,,,,,,,, 9R99FEIR,conferencePaper,2005,"Brooks, A.; Petersson, E.",Recursive reflection and learning in raw data video analysis of interactive 'play' environments for special needs health care,"Proceedings of 7th International Workshop on Enterprise networking and Computing in Healthcare Industry, 2005. HEALTHCOM 2005.",978-0-7803-8940-3,,10.1109/HEALTH.2005.1500399,http://ieeexplore.ieee.org/document/1500399/,,2005,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,83-87,,,,,,,,,,,IEEE,"Busan, South Korea",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,7th International Workshop on Enterprise Networking and Computing in Healthcare Industry. HEALTHCOM 2005,,,,,,,,,,,,,,, 7UD4C8ZA,conferencePaper,2008,"Gopakumar, B.; Wang, S.; Khasawneh, M. T.; Cummings, D.; Srihari, K.",Reengineering radiology transcription process through Voice Recognition,2008 IEEE International Conference on Industrial Engineering and Engineering Management,978-1-4244-2629-4,,10.1109/IEEM.2008.4737940,http://ieeexplore.ieee.org/document/4737940/,,2008-12,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,604-608,,,,,,,,,,,IEEE,"Singapore, Singapore",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2008 IEEE International Conference on Industrial Engineering and Engineering Management (IEEM),,,,,,,,,,,,,,, CMK3RNHZ,conferencePaper,2013,"Chen, Guoshun; Wang, Gefang; Cao, Wenbin",Regression based complex equipment Prognostic and Health Management,"2013 International Conference on Quality, Reliability, Risk, Maintenance, and Safety Engineering (QR2MSE)",978-1-4799-1016-8 978-1-4799-1014-4,,10.1109/QR2MSE.2013.6625949,http://ieeexplore.ieee.org/document/6625949/,,2013-07,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,1893-1896,,,,,,,,,,,IEEE,"Chengdu, China",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2013 International Conference on Quality, Reliability, Risk, Maintenance, and Safety Engineering (QR2MSE)",,,,,,,,,,,,,,, HBMAA9U4,conferencePaper,2015,"George, Elizabeth; Khan, Shamsuddin S",Reinforcement learning for taxi-out time prediction: An improved Q-learning approach,2015 International Conference on Computing and Network Communications (CoCoNet),978-1-4673-7309-8,,10.1109/CoCoNet.2015.7411275,http://ieeexplore.ieee.org/document/7411275/,,2015-12,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,757-764,,,,,,Reinforcement learning for taxi-out time prediction,,,,,IEEE,"Trivandrum, India",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 International Conference on Computing and Network Communications (CoCoNet),,,,,,,,,,,,,,, BG8EWTR9,conferencePaper,2016,"Afzal, Muhammad; Lee, Sungyoung",Relevant evidence acquisition and appraisal using knowledge-intensive queries,2016 18th International Conference on Advanced Communication Technology (ICACT),978-89-968650-6-3,,10.1109/ICACT.2016.7423528,http://ieeexplore.ieee.org/document/7423528/,,2016-01,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,703-709,,,,,,,,,,,IEEE,"Pyeongchang Kwangwoon Do, South Korea",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 18th International Conference on Advanced Communication Technology (ICACT),,,,,,,,,,,,,,, S8XMRXXM,conferencePaper,2015,"Murr, G. El; Griffo, A.; Wang, J.; Zhu, Z. Q.; Mecrow, B.",Reliability assessment of fault tolerant permanent magnet AC drives,IECON 2015 - 41st Annual Conference of the IEEE Industrial Electronics Society,978-1-4799-1762-4,,10.1109/IECON.2015.7392522,http://ieeexplore.ieee.org/document/7392522/,,2015-11,21/11/2018 11:55,14/04/2020 08:35,21/11/2018 11:55,002777-002782,,,,,,,,,,,IEEE,Yokohama,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IECON 2015 - 41st Annual Conference of the IEEE Industrial Electronics Society,,,,,,,,,,,,,,, FRBXMKFJ,conferencePaper,2009,"Wei Hu; Foitzik, Bertram; Chi-Thuan Cao; Guhmann, Clemens",Reliability based lifetime prediction and optimization for permanent magnet synchronous machines,"2009 6th International Multi-Conference on Systems, Signals and Devices",978-1-4244-4345-1,,10.1109/SSD.2009.4956655,http://ieeexplore.ieee.org/document/4956655/,,2009-03,21/11/2018 11:55,14/04/2020 08:35,21/11/2018 11:55,01-Jun,,,,,,,,,,,IEEE,"Djerba, Tunisia",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2009 6th International Multi-Conference on Systems, Signals and Devices (SSD)",,,,,,,,,,,,,,, VG6EEBVP,conferencePaper,2013,"Schwerz, R.; Boehme, B.; Roellig, M.; Wolter, K.-J.; Meyendorf, N.",Reliability of embedding concepts for discrete passive components in organic circuit boards,2013 IEEE 63rd Electronic Components and Technology Conference,978-1-4799-0232-3 978-1-4799-0233-0,,10.1109/ECTC.2013.6575734,http://ieeexplore.ieee.org/document/6575734/,,2013-05,21/11/2018 11:55,14/04/2020 08:35,21/11/2018 11:55,1243-1251,,,,,,,,,,,IEEE,"Las Vegas, NV, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2013 IEEE 63rd Electronic Components and Technology Conference (ECTC),,,,,,,,,,,,,,, RWFU9WR8,conferencePaper,2014,"Wei, Qidong; Xu, Dan",Remaining useful life estimation based on gamma process considered with measurement error,"2014 10th International Conference on Reliability, Maintainability and Safety (ICRMS)",978-1-4799-6632-5,,10.1109/ICRMS.2014.7107275,http://ieeexplore.ieee.org/document/7107275/,,2014-08,21/11/2018 11:55,14/04/2020 08:35,21/11/2018 11:55,645-649,,,,,,,,,,,IEEE,"Guangzhou, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2014 International Conference on Reliability, Maintainability and Safety (ICRMS)",,,,,,,,,,,,,,, QKHUCUL5,conferencePaper,2016,"Xue, Xiaoling; Hu, Yanyan; Qi, Shuai",Remaining useful life estimation for proton exchange membrane fuel cell based on extreme learning machine,2016 31st Youth Academic Annual Conference of Chinese Association of Automation (YAC),978-1-5090-4423-8,,10.1109/YAC.2016.7804863,http://ieeexplore.ieee.org/document/7804863/,,2016-11,21/11/2018 11:55,14/04/2020 08:35,21/11/2018 11:55,43-47,,,,,,,,,,,IEEE,"Wuhan, Hubei Province, China",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 31st Youth Academic Annual Conference of Chinese Association of Automation (YAC),,,,,,,,,,,,,,, A8CTHLY4,journalArticle,2009,"Niyato, Dusit; Hossain, Ekram; Camorlinga, Sergio",Remote patient monitoring service using heterogeneous wireless access networks: architecture and optimization,IEEE Journal on Selected Areas in Communications,,0733-8716,10.1109/JSAC.2009.090506,http://ieeexplore.ieee.org/document/4909280/,,2009-05,21/11/2018 11:55,14/04/2020 08:35,21/11/2018 11:55,412-423,,4,27,,,Remote patient monitoring service using heterogeneous wireless access networks,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GDTQGTZ9,conferencePaper,2011,"Boudahri, Fethi; Sari, Zaki; Bennekrouf, Mohammed",Renovation of a distribution network of poultry products: Application city of Tlemcen (ALGERIA),2011 4th International Conference on Logistics,978-1-4577-0322-5,,10.1109/LOGISTIQUA.2011.5939412,http://ieeexplore.ieee.org/document/5939412/,,2011-05,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,115-121,,,,,,Renovation of a distribution network of poultry products,,,,,IEEE,"Hammamet, Tunisia",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2011 4th International Conference on Logistics (LOGISTIQUA),,,,,,,,,,,,,,, PM8GWBJF,conferencePaper,2001,"Vincent, B.; Pritchett, A.R.",Requirements specification for health monitoring systems capable of resolving flight control system faults,20th DASC. 20th Digital Avionics Systems Conference (Cat. No.01CH37219),978-0-7803-7034-0,,10.1109/DASC.2001.963357,http://ieeexplore.ieee.org/document/963357/,,2001,21/11/2018 11:55,14/04/2020 08:35,21/11/2018 11:55,3D4/1-3D4/8,,,1,,,,,,,,IEEE,"Daytona Beach, FL, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,20th DASC. 20th Digital Avionics Systems Conference. Proceedings,,,,,,,,,,,,,,, KB8PUNDD,conferencePaper,2011,"xiaoxiong, Liu; Yuan, Sun Li; Zhiyi, Huang; Kang, Chen",Research of actuator fault health management method based on neural network,2011 International Conference of Soft Computing and Pattern Recognition (SoCPaR),978-1-4577-1196-1 978-1-4577-1195-4 978-1-4577-1194-7,,10.1109/SoCPaR.2011.6089111,http://ieeexplore.ieee.org/document/6089111/,,2011-10,21/11/2018 11:55,14/04/2020 08:35,21/11/2018 11:55,227-230,,,,,,,,,,,IEEE,"Dalian, China",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2011 International Conference of Soft Computing and Pattern Recognition (SoCPaR),,,,,,,,,,,,,,, BGIJ76JY,conferencePaper,2011,"Guo, Yingnan; Wan, Fangyi; Wu, Ling; Jiang, Hanjie",Research of structural health monitoring based on mode analysis for UAV wings,2011 Prognostics and System Health Managment Confernece,978-1-4244-7951-1,,10.1109/PHM.2011.5939521,http://ieeexplore.ieee.org/document/5939521/,,2011-05,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,01-Apr,,,,,,,,,,,IEEE,"Shenzhen, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2011 Prognostics and System Health Management Conference (PHM-2011 Shenzhen),,,,,,,,,,,,,,, LSFRA4PV,conferencePaper,2011,"Zhang, Yingbo; Zhao, Xinhui; Liu, Wei; Zhang, Jianrong; Jia, Yunxian; Feng, Tianle",Research on gearbox wearing prognosis based on Gamma-State Space Model,"The Proceedings of 2011 9th International Conference on Reliability, Maintainability and Safety",978-1-61284-667-5,,10.1109/ICRMS.2011.5979316,http://ieeexplore.ieee.org/document/5979316/,,2011-06,21/11/2018 11:55,14/04/2020 08:35,21/11/2018 11:55,279-283,,,,,,,,,,,IEEE,"Guiyang, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2011 9th International Conference on Reliability, Maintainability and Safety (ICRMS 2011)",,,,,,,,,,,,,,, 7ISPFFAT,conferencePaper,2011,"Yong-shuang, Shang; Ding-guo, Wang; Wen-hai, Li; Zhong-de, Wu",Research on Integrated Grounds Health Management for aviation gyroscope,Proceedings of 2011 International Conference on Electronic & Mechanical Engineering and Information Technology,978-1-61284-087-1,,10.1109/EMEIT.2011.6023996,http://ieeexplore.ieee.org/document/6023996/,,2011-08,21/11/2018 11:55,14/04/2020 08:35,21/11/2018 11:55,4333-4336,,,,,,,,,,,IEEE,"Harbin, Heilongjiang, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Mechanical Engineering and Information Technology (EMEIT),,,,,,,,,,,,,,, 2SFFB93C,conferencePaper,2016,"Xu, Yejia; Shi, Meixia",Research on optimal mixed health insurance contact based on risk sharing,2016 International Conference on Industrial Economics System and Industrial Security Engineering (IEIS),978-1-5090-1105-6,,10.1109/IEIS.2016.7551880,http://ieeexplore.ieee.org/document/7551880/,,2016-07,21/11/2018 11:55,14/04/2020 08:35,21/11/2018 11:55,01-May,,,,,,,,,,,IEEE,"Sydney, Australia",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 International Conference on Industrial Economics System and Industrial Security Engineering (IEIS),,,,,,,,,,,,,,, HBGQRMR8,conferencePaper,2010,"Huang, Deyin; Liu, Mao; Zhang, Jing; Wang, Yang",Research on risk assessment based on Monte Carlo simulation and dose-response multistage model,2010 3rd International Conference on Biomedical Engineering and Informatics,978-1-4244-6498-2 978-1-4244-6495-1 978-1-4244-6497-5,,10.1109/BMEI.2010.5639276,http://ieeexplore.ieee.org/document/5639276/,,2010-10,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,1245-1250,,,,,,,,,,,IEEE,"Yantai, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2010 3rd International Conference on Biomedical Engineering and Informatics (BMEI),,,,,,,,,,,,,,, GI5EZCVD,conferencePaper,2012,"Cortes, L. M. P.; Zurakowski, R.",Resistance evolution in HIV — Modeling when to intervene,2012 American Control Conference (ACC),978-1-4577-1096-4 978-1-4577-1095-7 978-1-4577-1094-0 978-1-4673-2102-0,,10.1109/ACC.2012.6315693,http://ieeexplore.ieee.org/document/6315693/,,2012-06,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,4053-4058,,,,,,,,,,,IEEE,"Montreal, QC",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 American Control Conference - ACC 2012,,,,,,,,,,,,,,, 46W43NXR,conferencePaper,2009,"Albers, Rob; Suijs, Eric; de With, Peter H.N.",Resource usage prediction for groups of dynamic image-processing tasks using Markov modeling,"2009 IEEE International Conference on Acoustics, Speech and Signal Processing",978-1-4244-2353-8,,10.1109/ICASSP.2009.4959987,http://ieeexplore.ieee.org/document/4959987/,,2009-04,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,1929-1932,,,,,,,,,,,IEEE,"Taipei, Taiwan",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"ICASSP 2009 - 2009 IEEE International Conference on Acoustics, Speech and Signal Processing",,,,,,,,,,,,,,, Y4AWP43H,conferencePaper,2012,"Bill Chun Piu Lau; Eden Wai Man Ma; Pecht, Michael",Review of offshore wind turbine failures and fault prognostic methods,Proceedings of the IEEE 2012 Prognostics and System Health Management Conference (PHM-2012 Beijing),978-1-4577-1911-0 978-1-4577-1909-7 978-1-4577-1910-3,,10.1109/PHM.2012.6228954,http://ieeexplore.ieee.org/document/6228954/,,2012-05,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,01-May,,,,,,,,,,,IEEE,"Beijing, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 Prognostics and System Health Management Conference (PHM),,,,,,,,,,,,,,, HRNJSKMI,conferencePaper,2016,"Jebali, Nada; Beldi, Sabri; Gharsallah, Ali",RFID antennas implanted for pervasive healthcare applications,"2016 7th International Conference on Sciences of Electronics, Technologies of Information and Telecommunications (SETIT)",978-1-5090-4712-3,,10.1109/SETIT.2016.7939857,http://ieeexplore.ieee.org/document/7939857/,,2016-12,21/11/2018 11:55,14/04/2020 08:34,21/11/2018 11:55,149-152,,,,,,,,,,,IEEE,"Hammamet, Tunisia",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2016 7th International Conference on Sciences of Electronics, Technologies of Information and Telecommunications (SETIT)",,,,,,,,,,,,,,, RVASFRZM,conferencePaper,2010,"Kalimeri, Kyriaki; Matic, Aleksandar; Cappelletti, Alessandro",RFID: Recognizing failures in dressing activity,Proceedings of the 4th International ICST Conference on Pervasive Computing Technologies for Healthcare,978-963-9799-89-9,,10.4108/ICST.PERVASIVEHEALTH2010.8896,http://eudl.eu/doi/10.4108/ICST.PERVASIVEHEALTH2010.8896,,2010,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,,,,,,,RFID,,,,,IEEE,"Munchen, Germany",en,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,4th International ICST Conference on Pervasive Computing Technologies for Healthcare,,,,,,,,,,,,,,, VF28KQGU,conferencePaper,2005,"Kar-Ming Cheung; Ko, A.; Dang, V.; Heckman, D.",Risk analysis for nondeterministic mission planning and sequencing,2005 IEEE Aerospace Conference,978-0-7803-8870-3,,10.1109/AERO.2005.1559308,http://ieeexplore.ieee.org/document/1559308/,,2005,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,147-158,,,,,,,,,,,IEEE,"Big Sky, MT, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2005 IEEE Aerospace Conference,,,,,,,,,,,,,,, EMJVRZCE,journalArticle,2017,"Chang, Yanling; Erera, Alan L.; White, Chelsea C.",Risk Assessment of Deliberate Contamination of Food Production Facilities,"IEEE Transactions on Systems, Man, and Cybernetics: Systems",,"2168-2216, 2168-2232",10.1109/TSMC.2015.2500822,http://ieeexplore.ieee.org/document/7339706/,,2017-03,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,381-393,,3,47,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GR8QT94R,conferencePaper,2008,"Stoian, I.; Ungureanu, G.; Mircea, M.; Moldovan, Z.; Cristea, M.V.; Imre, A.",Rivers water quality monitoring modeling and simulation of pollutants propagation,"2008 IEEE International Conference on Automation, Quality and Testing, Robotics",978-1-4244-2576-1,,10.1109/AQTR.2008.4588747,http://ieeexplore.ieee.org/document/4588747/,,2008,21/11/2018 11:56,14/04/2020 08:35,21/11/2018 11:56,267-270,,,,,,,,,,,IEEE,"Cluj-Napoca, Romania",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2008 IEEE International Conference on Automation, Quality and Testing, Robotics",,,,,,,,,,,,,,, 64LPXBTX,conferencePaper,2009,"Miro, Jaime Valls; Osswald, Vivien; Patel, Mitesh; Dissanayake, Gamini",Robotic assistance with attitude: A mobility agent for motor function rehabilitation and ambulation support,2009 IEEE International Conference on Rehabilitation Robotics,978-1-4244-3788-7,,10.1109/ICORR.2009.5209523,http://ieeexplore.ieee.org/document/5209523/,,2009-06,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,529-534,,,,,,Robotic assistance with attitude,,,,,IEEE,"Kyoto, Japan",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,the Community (ICORR),,,,,,,,,,,,,,, WAEXUR58,journalArticle,2017,"Garcia-Escudero, Luis Angel; Duque-Perez, Oscar; Fernandez-Temprano, Miguel; Morinigo-Sotelo, Daniel",Robust Detection of Incipient Faults in VSI-Fed Induction Motors Using Quality Control Charts,IEEE Transactions on Industry Applications,,"0093-9994, 1939-9367",10.1109/TIA.2016.2617300,http://ieeexplore.ieee.org/document/7590081/,,2017-05,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,3076-3085,,3,53,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YE3QSPYG,journalArticle,2018,"Abd El-Latif, Ahmed A.; Abd-El-Atty, Bassem; Talha, Muhammad",Robust Encryption of Quantum Medical Images,IEEE Access,,2169-3536,10.1109/ACCESS.2017.2777869,http://ieeexplore.ieee.org/document/8119911/,,2018,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,1073-1081,,,6,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, H5W6PGXX,conferencePaper,2009,"Jiang, Shanshan; Xue, Yuan; Giani, Annarita; Bajcsy, Ruzena",Robust Medical Data Delivery for Wireless Pervasive Healthcare,"2009 Eighth IEEE International Conference on Dependable, Autonomic and Secure Computing",978-1-4244-5420-4 978-0-7695-3929-4,,10.1109/DASC.2009.87,http://ieeexplore.ieee.org/document/5380598/,,2009-12,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,802-807,,,,,,,,,,,IEEE,"Chengdu, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2009 International Conference on Dependable, Autonomic and Secure Computing (DASC)",,,,,,,,,,,,,,, X7WTYDB4,journalArticle,2011,"Rougier, Caroline; Meunier, Jean; St-Arnaud, Alain; Rousseau, Jacqueline",Robust Video Surveillance for Fall Detection Based on Human Shape Deformation,IEEE Transactions on Circuits and Systems for Video Technology,,"1051-8215, 1558-2205",10.1109/TCSVT.2011.2129370,http://ieeexplore.ieee.org/document/5733403/,,2011-05,21/11/2018 11:56,14/04/2020 08:35,21/11/2018 11:56,611-622,,5,21,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5X6VILDF,conferencePaper,2018,"Dai, Raipeng; Zhao, Yang; Chen, Guihai; Dou, Wanchun; Tian, Chen; Wu, Xiaobing; He, Tian",Robustly Safe Charging for Wireless Power Transfer,IEEE INFOCOM 2018 - IEEE Conference on Computer Communications,978-1-5386-4128-6,,10.1109/INFOCOM.2018.8485951,https://ieeexplore.ieee.org/document/8485951/,,2018-04,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,378-386,,,,,,,,,,,IEEE,"Honolulu, HI",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEEE INFOCOM 2018 - IEEE Conference on Computer Communications,,,,,,,,,,,,,,, NN3GAX3Z,conferencePaper,2015,"Akinwande, Olumide J.; Huibo Bi",Routing diverse crowds in emergency with dynamic grouping,2015 IEEE International Conference on Pervasive Computing and Communication Workshops (PerCom Workshops),978-1-4799-8425-1,,10.1109/PERCOMW.2015.7134086,http://ieeexplore.ieee.org/document/7134086/,,2015-03,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,487-492,,,,,,,,,,,IEEE,"St. Louis, MO",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 IEEE International Conference on Pervasive Computing and Communication Workshops (PerCom Workshops),,,,,,,,,,,,,,, AQWXFNBN,conferencePaper,2012,"Ardestani, Ali; Nemati, Hamid; Eleti, Omprakash; Sadri, Fereidon",RxSem: A rule based semantic integration method for medical informatics,2012 IEEE 13th International Conference on Information Reuse & Integration (IRI),978-1-4673-2284-3 978-1-4673-2282-9 978-1-4673-2283-6,,10.1109/IRI.2012.6303059,http://ieeexplore.ieee.org/document/6303059/,,2012-08,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,564-571,,,,,,RxSem,,,,,IEEE,"Las Vegas, NV, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 IEEE 13th International Conference on Information Reuse & Integration (IRI),,,,,,,,,,,,,,, QNQLHNMQ,journalArticle,2017,"Dai, Haipeng; Liu, Yunhuai; Chen, Guihai; Wu, Xiaobing; He, Tian; Liu, Alex X.; Ma, Huizhen",Safe Charging for Wireless Power Transfer,IEEE/ACM Transactions on Networking,,"1063-6692, 1558-2566",10.1109/TNET.2017.2750323,http://ieeexplore.ieee.org/document/8051273/,,2017-12,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,3531-3544,,6,25,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 34XEVWR8,conferencePaper,2014,"Dai, Haipeng; Liu, Yunhuai; Chen, Guihai; Wu, Xiaobing; He, Tian",Safe Charging for wireless power transfer,IEEE INFOCOM 2014 - IEEE Conference on Computer Communications,978-1-4799-3360-0,,10.1109/INFOCOM.2014.6848041,http://ieeexplore.ieee.org/document/6848041/,,2014-04,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,1105-1113,,,,,,,,,,,IEEE,"Toronto, ON, Canada",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEEE INFOCOM 2014 - IEEE Conference on Computer Communications,,,,,,,,,,,,,,, UTLDT4D2,conferencePaper,2017,"Alhassoun, Nailah Saleh; Uddin, Md Yusuf Sarwar; Venkatasubramanian, Nalini",SAFER: An IoT-based perpetual safe community awareness and alerting network,2017 Eighth International Green and Sustainable Computing Conference (IGSC),978-1-5386-3470-7,,10.1109/IGCC.2017.8323585,http://ieeexplore.ieee.org/document/8323585/,"Perpetual awareness systems are sensing systems characterized by continuous monitoring and ubiquitous sensing; they are essential to many safety and mission-critical applications, e.g. assisted living, healthcare and public safety. In this paper, we present SAFER, a perpetual heterogeneous IoT system; deployed in homes to detect critical events (injury, hazardous-environment) that must trigger immediate action and response. A key challenge here is the energy consumption associated with perpetual operations. We propose a novel energy-aware perpetual home IoT system where battery-operated and wall-powered IoT devices co-execute to ensure safety of occupants. We use a semantic approach that extracts activities-of-daily-living from device data to drive energy-optimized sensor activations. To validate our approach, we developed an elderly fall detection system using multi-personal and in-situ sensing devices. Using initial measurements to drive larger simulations, we show that our Cost-Function-Gradient algorithm can achieve greater than 4X reductions in energy dissipation without loss of sensing accuracy.",2017-10,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,01-Aug,,,,,,SAFER,,,,,IEEE,"Orlando, FL",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 Eighth International Green and Sustainable Computing Conference (IGSC),,,,,,,,,,,,,,, RN4RAJBI,conferencePaper,2011,"Hossain, M. Shamim; Hossain, M. Anwar; Saddik, Abdulmotaleb El",Scalable service configuration for ubiquitous health,2011 IEEE International Instrumentation and Measurement Technology Conference,978-1-4244-7933-7,,10.1109/IMTC.2011.5944165,http://ieeexplore.ieee.org/document/5944165/,,2011-05,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,01-May,,,,,,,,,,,IEEE,"Hangzhou, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2011 IEEE International Instrumentation and Measurement Technology Conference (I2MTC),,,,,,,,,,,,,,, KRRFI476,conferencePaper,2011,,Scenario configuration for fluid spill in urban dynamic spaces,2011 6th Colombian Computing Congress (CCC),978-1-4577-0285-3,,10.1109/COLOMCC.2011.5936320,http://ieeexplore.ieee.org/document/5936320/,,2011-05,21/11/2018 11:56,14/04/2020 08:35,21/11/2018 11:56,01-Jun,,,,,,,,,,,IEEE,"Manizales, Colombia",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2011 6th Colombian Computing Congress (CCC),,,,,,,,,,,,,,, W5TWJNZL,conferencePaper,2015,"Wong, Zoie Shui-Yee; Goldsman, David; Tsui, Kwok-Leung",School closure strategies for the 2009 Hong Kong H1N1 influenza pandemic,2015 Winter Simulation Conference (WSC),978-1-4673-9743-8,,10.1109/WSC.2015.7408551,http://ieeexplore.ieee.org/document/7408551/,,2015-12,21/11/2018 11:56,14/04/2020 08:35,21/11/2018 11:56,3961-3972,,,,,,,,,,,IEEE,"Huntington Beach, CA, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 Winter Simulation Conference (WSC),,,,,,,,,,,,,,, 7S29DB7Z,conferencePaper,2017,"Leeuwen, Cornelis Jan van; Yildirim, Kasim Sinan; Pawelczak, Przemyslaw",Self Adaptive Safe Provisioning of Wireless Power Using DCOPs,2017 IEEE 11th International Conference on Self-Adaptive and Self-Organizing Systems (SASO),978-1-5090-6555-4,,10.1109/SASO.2017.16,http://ieeexplore.ieee.org/document/8064031/,,2017-09,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,71-80,,,,,,,,,,,IEEE,"Tucson, AZ, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 IEEE 11th International Conference on Self-Adaptive and Self-Organizing Systems (SASO),,,,,,,,,,,,,,, JA89DHIX,conferencePaper,2016,"Carlini, Emanuele; Coppola, Massimo; Dazzi, Patrizio; Mordacchini, Matteo; Passarella, Andrea",Self-Optimising Decentralised Service Placement in Heterogeneous Cloud Federation,2016 IEEE 10th International Conference on Self-Adaptive and Self-Organizing Systems (SASO),978-1-5090-3534-2,,10.1109/SASO.2016.17,http://ieeexplore.ieee.org/document/7774392/,,2016-09,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,110-119,,,,,,,,,,,IEEE,"Augsburg, Germany",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 IEEE 10th International Conference on Self-Adaptive and Self-Organizing Systems (SASO),,,,,,,,,,,,,,, VB7LXFIA,conferencePaper,2016,"Penghong Guo; Rivera, Daniel E.; Downs, Danielle S.; Savage, Jennifer S.",Semi-physical identification and state estimation of energy intake for interventions to manage gestational weight gain,2016 American Control Conference (ACC),978-1-4673-8682-1,,10.1109/ACC.2016.7525092,http://ieeexplore.ieee.org/document/7525092/,,2016-07,21/11/2018 11:56,14/04/2020 08:35,21/11/2018 11:56,1271-1276,,,,,,,,,,,IEEE,"Boston, MA, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 American Control Conference (ACC),,,,,,,,,,,,,,, UBVTK6B3,conferencePaper,2015,"Kaswekar, P.; Wagner, J. F.",Sensor fusion based vibration estimation using inertial sensors for a complex lightweight structure,2015 DGON Inertial Sensors and Systems Symposium (ISS),978-1-4673-6738-7,,10.1109/InertialSensors.2015.7314265,http://ieeexplore.ieee.org/document/7314265/,,2015-09,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,Jan-20,,,,,,,,,,,IEEE,"Karlsruhe, Germany",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 DGON Inertial Sensors and Systems Symposium (ISS),,,,,,,,,,,,,,, Q4NHBKUI,conferencePaper,2009,"Zhang, Chongming; Zhou, Xi; Gao, Chuanshan; Wang, Chunmei; Wu, Huafeng",Sensor Health Monitoring in Wireless Sensor Networks,2009 WASE International Conference on Information Engineering,978-0-7695-3679-8,,10.1109/ICIE.2009.168,http://ieeexplore.ieee.org/document/5211078/,,2009-07,21/11/2018 11:56,14/04/2020 08:35,21/11/2018 11:56,337-341,,,,,,,,,,,IEEE,"Taiyuan, Shanxi, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2009 WASE International Conference on Information Engineering (ICIE),,,,,,,,,,,,,,, 8L2D8S3P,conferencePaper,2016,"Dash, Shitikantha; Dash, Dipak Kumar",Serverless cloud computing framework for smart grid architecture,2016 IEEE 7th Power India International Conference (PIICON),978-1-4673-8962-4,,10.1109/POWERI.2016.8077240,http://ieeexplore.ieee.org/document/8077240/,,2016-11,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,01-Jun,,,,,,,,,,,IEEE,"Bikaner, Rajasthan, India",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 IEEE 7th Power India International Conference (PIICON),,,,,,,,,,,,,,, RZNI48ZM,conferencePaper,2018,"Vrind, Tushar; Sharma, Diwakar; Pathak, Lalit; Das, Debabrata",Session cloning protocol between smart devices for connected and un-connected states in B4G and 5G,2018 15th IEEE Annual Consumer Communications & Networking Conference (CCNC),978-1-5386-4790-5,,10.1109/CCNC.2018.8319191,http://ieeexplore.ieee.org/document/8319191/,,2018-01,21/11/2018 11:56,14/04/2020 08:35,21/11/2018 11:56,01-Aug,,,,,,,,,,,IEEE,"Las Vegas, NV",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2018 15th IEEE Annual Consumer Communications & Networking Conference (CCNC),,,,,,,,,,,,,,, N8AUJU8F,conferencePaper,2016,"Wang, Hao; Kolmanovsky, Ilya; Sun, Jing",Set-membership condition monitoring framework for dual fuel engines,2016 American Control Conference (ACC),978-1-4673-8682-1,,10.1109/ACC.2016.7525426,http://ieeexplore.ieee.org/document/7525426/,,2016-07,21/11/2018 11:56,14/04/2020 08:35,21/11/2018 11:56,3298-3303,,,,,,,,,,,IEEE,"Boston, MA, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 American Control Conference (ACC),,,,,,,,,,,,,,, KK8QGC3L,conferencePaper,2012,"Aung, Yee Mon; Al-Jumaily, Adel",Shoulder rehabilitation with biofeedback simulation,2012 IEEE International Conference on Mechatronics and Automation,978-1-4673-1278-3 978-1-4673-1275-2 978-1-4673-1277-6,,10.1109/ICMA.2012.6283382,http://ieeexplore.ieee.org/document/6283382/,,2012-08,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,974-979,,,,,,,,,,,IEEE,"Chengdu, China",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 IEEE International Conference on Mechatronics and Automation (ICMA),,,,,,,,,,,,,,, AJN7VDG5,conferencePaper,2016,"Roland, Theresa; Baumgartner, Werner; Amsuess, Sebastian; Russold, Michael Friedrich",Signal evaluation of capacitive EMG for upper limb prostheses control using an ultra-low-power microcontroller,2016 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES),978-1-4673-7791-1,,10.1109/IECBES.2016.7843465,http://ieeexplore.ieee.org/document/7843465/,,2016-12,21/11/2018 11:56,14/04/2020 08:35,21/11/2018 11:56,317-320,,,,,,,,,,,IEEE,Malaysia,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES),,,,,,,,,,,,,,, J4E6X2NU,conferencePaper,2013,"Bisset, K. R.; Deodhar, S.; Makkapati, H.; Marathe, M. V.; Stretz, P.; Barrett, C. L.",Simfrastructure: A Flexible and Adaptable Middleware Platform for Modeling and Analysis of Socially Coupled Systems,"2013 13th IEEE/ACM International Symposium on Cluster, Cloud, and Grid Computing",978-0-7695-4996-5 978-1-4673-6465-2,,10.1109/CCGrid.2013.78,http://ieeexplore.ieee.org/document/6546132/,,2013-05,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,506-513,,,,,,Simfrastructure,,,,,IEEE,Delft,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2013 13th IEEE/ACM International Symposium on Cluster, Cloud and Grid Computing (CCGrid)",,,,,,,,,,,,,,, ER7R6PA7,conferencePaper,2015,"Zhao, Liang; Chen, Jiangzhuo; Chen, Feng; Wang, Wei; Lu, Chang-Tien; Ramakrishnan, Naren",SimNest: Social Media Nested Epidemic Simulation via Online Semi-Supervised Deep Learning,2015 IEEE International Conference on Data Mining,978-1-4673-9504-5,,10.1109/ICDM.2015.39,http://ieeexplore.ieee.org/document/7373368/,,2015-11,21/11/2018 11:56,14/04/2020 08:35,21/11/2018 11:56,639-648,,,,,,SimNest,,,,,IEEE,"Atlantic City, NJ, USA",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 IEEE International Conference on Data Mining (ICDM),,,,,,,,,,,,,,, F4P3YAEE,conferencePaper,2012,"Bisset, Keith R.; Aji, Ashwin M.; Bohm, Eric; Kale, Laxmikant V.; Kamal, Tariq; Marathe, Madhav V.; Yeom, Jae-Seung",Simulating the Spread of Infectious Disease over Large Realistic Social Networks Using Charm++,2012 IEEE 26th International Parallel and Distributed Processing Symposium Workshops & PhD Forum,978-1-4673-0974-5,,10.1109/IPDPSW.2012.65,http://ieeexplore.ieee.org/document/6270685/,,2012-05,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,507-518,,,,,,,,,,,IEEE,"Shanghai, China",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 26th IEEE International Parallel and Distributed Processing Symposium Workshops (IPDPSW),,,,,,,,,,,,,,, 36QCCVEH,conferencePaper,2016,"Dattatraya, Patil Yogita; Agarkhed, Jayashree",Simulation an art of performance evaluation in wireless sensor networks,"2016 International Conference on Circuit, Power and Computing Technologies (ICCPCT)",978-1-5090-1277-0,,10.1109/ICCPCT.2016.7530235,http://ieeexplore.ieee.org/document/7530235/,,2016-03,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,01-May,,,,,,,,,,,IEEE,"Nagercoil, India",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2016 International Conference on Circuit, Power and Computing Technologies (ICCPCT)",,,,,,,,,,,,,,, N5D5K764,conferencePaper,2002,"Turtiainen, A.; Mannila, T.; Kuusiluoma, S.; Korpinen, L.",Simulation game in teaching electric economics,IEEE/PES Transmission and Distribution Conference and Exhibition,978-0-7803-7525-3,,10.1109/TDC.2002.1177764,http://ieeexplore.ieee.org/document/1177764/,,2002,21/11/2018 11:56,14/04/2020 08:35,21/11/2018 11:56,1986-1989,,,3,,,,,,,,IEEE,"Yokohama, Japan",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Asia Pacific Conference and Exhibition of the IEEE-Power Engineering Society on Transmission and Distribution,,,,,,,,,,,,,,, IQ6KJYXW,conferencePaper,2005,"Bei Jin; Zhuming Ai; Rasmussen, M.",Simulation of Eye Disease in Virtual Reality,2005 IEEE Engineering in Medicine and Biology 27th Annual Conference,978-0-7803-8741-6,,10.1109/IEMBS.2005.1615631,http://ieeexplore.ieee.org/document/1615631/,,2005,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,5128-5131,,,,,,,,,,,IEEE,"Shanghai, China",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2005 IEEE Engineering in Medicine and Biology 27th Annual Conference,,,,,,,,,,,,,,, N56IV4WE,conferencePaper,2011,"Wu, Yun; Wan, Fangyi; Sun, Mingming",Simulation on the faults mechanism of wing structure,2011 Prognostics and System Health Managment Confernece,978-1-4244-7951-1,,10.1109/PHM.2011.5939522,http://ieeexplore.ieee.org/document/5939522/,,2011-05,21/11/2018 11:56,14/04/2020 08:35,21/11/2018 11:56,01-Jul,,,,,,,,,,,IEEE,"Shenzhen, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2011 Prognostics and System Health Management Conference (PHM-2011 Shenzhen),,,,,,,,,,,,,,, G3AVBVTH,conferencePaper,2017,"Lee, Hyeongsuk; Kim, Jeongeun; Kim, Sukwha; Lee, Jisan; Byun, Ahjung; Ryu, Hyeongju; Kong, Hyoun-Joong",Simulation to assess user needs for the development of a bedside robot,2017 14th International Conference on Ubiquitous Robots and Ambient Intelligence (URAI),978-1-5090-3056-9,,10.1109/URAI.2017.7992705,http://ieeexplore.ieee.org/document/7992705/,,2017-06,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,179-180,,,,,,,,,,,IEEE,Jeju,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 14th International Conference on Ubiquitous Robots and Ambient Intelligence (URAI),,,,,,,,,,,,,,, CLFXINW4,conferencePaper,2013,"Akhavian, Reza; Behzadan, Amir H.",Simulation-based evaluation of fuel consumption in heavy construction projects by monitoring equipment idle times,2013 Winter Simulations Conference (WSC),978-1-4799-3950-3 978-1-4799-2077-8,,10.1109/WSC.2013.6721677,http://ieeexplore.ieee.org/document/6721677/,,2013-12,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,3098-3108,,,,,,,,,,,IEEE,"Washington, DC, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2013 Winter Simulation Conference - (WSC 2013),,,,,,,,,,,,,,, EDCW7YWI,conferencePaper,2010,"Koo, Pyung-Hoi; Nielsen, Karl Brian; Jang, Jaejin; Kolker, Alexander",Simulation-based patient flow analysis in an endoscopy unit,2010 IEEE Workshop on Health Care Management (WHCM),978-1-4244-4997-2,,10.1109/WHCM.2010.5441266,http://ieeexplore.ieee.org/document/5441266/,"One of the major elements in improving efficiency of healthcare services is patient flow. Patients require a variety of healthcare resources as they receive healthcare services. Poor management of patient flow results in long waiting time of patients, under/over utilization of medical resources, low quality of care and high healthcare cost. This article addresses patient flow problems at a Gastrointestinal endoscopy unit. We attempt to analyze the main factors that contribute to the inefficient patient flow and process bottlenecks and to propose efficient patient scheduling and staff allocation alternatives to increase the system efficiency. Simulation models are used to examine various healthcare operational strategies.",2010-02,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,01-Jun,,,,,,,,,,,IEEE,"Venice, Italy",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2010 IEEE Workshop on Health Care Management (WHCM),,,,,,,,,,,,,,, G6FUKTY3,conferencePaper,2013,"Kozlov, Mikhail; Turner, Robert",Simulation-driven design and optimization of RF coil arrays for MRI,2013 IEEE MTT-S International Microwave Workshop Series on RF and Wireless Technologies for Biomedical and Healthcare Applications (IMWS-BIO),978-1-4673-6096-8,,10.1109/IMWS-BIO.2013.6756144,http://ieeexplore.ieee.org/document/6756144/,,2013-12,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,01-Mar,,,,,,,,,,,IEEE,"Singapore, Singapore",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2013 IEEE MTT-S International Microwave Workshop Series on RF and Wireless Technologies for Biomedical and Healthcare Applications (IMWS-BIO),,,,,,,,,,,,,,, ZGA2Y4HF,conferencePaper,2009,"Sihver, L.; Sato, T.; Gustafsson, K.; Shurshakov, V.A.; Reitz, G.","Simulations of the MTR-R and MTR experiments at ISS, and shielding properties using PHITS",2009 IEEE Aerospace conference,978-1-4244-2621-8,,10.1109/AERO.2009.4839360,http://ieeexplore.ieee.org/document/4839360/,,2009-03,21/11/2018 11:56,14/04/2020 08:35,21/11/2018 11:56,01-Aug,,,,,,,,,,,IEEE,"Big Sky, MT, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2009 IEEE Aerospace conference,,,,,,,,,,,,,,, G5NI2W8I,journalArticle,2016,"Gu, Weixi; Shangguan, Longfei; Yang, Zheng; Liu, Yunhao",Sleep Hunter: Towards Fine Grained Sleep Stage Tracking with Smartphones,IEEE Transactions on Mobile Computing,,1536-1233,10.1109/TMC.2015.2462812,http://ieeexplore.ieee.org/document/7173047/,,01/06/2016,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,1514-1527,,6,15,,,Sleep Hunter,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2YMD2VWA,conferencePaper,2016,"Kilic, Tugba; Brunner, Valerie; Audoly, Laurent; Carrara, Sandro",Smart e-Patch for drugs monitoring in schizophrenia,"2016 IEEE International Conference on Electronics, Circuits and Systems (ICECS)",978-1-5090-6113-6,,10.1109/ICECS.2016.7841131,http://ieeexplore.ieee.org/document/7841131/,,2016-12,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,57-60,,,,,,,,,,,IEEE,"Monte Carlo, Monaco",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2016 IEEE International Conference on Electronics, Circuits and Systems (ICECS)",,,,,,,,,,,,,,, GZXL2SRT,journalArticle,2015,"Huang, Anpeng; Xie, Linzhen",SMART for mobile health: A study of scheduling algorithms in full-IP mobile networks,IEEE Communications Magazine,,0163-6804,10.1109/MCOM.2015.7045411,http://ieeexplore.ieee.org/document/7045411/,,2015-02,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,214-222,,2,53,,,SMART for mobile health,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, J4TY7SP4,conferencePaper,2010,"Hsiao, Jen-Hao; Chang, Henry",SmartDiet: A personal diet consultant for healthy meal planning,2010 IEEE 23rd International Symposium on Computer-Based Medical Systems (CBMS),978-1-4244-9167-4,,10.1109/CBMS.2010.6042681,http://ieeexplore.ieee.org/document/6042681/,,2010-10,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,421-425,,,,,,SmartDiet,,,,,IEEE,"Bentley, Australia",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2010 IEEE 23rd International Symposium on Computer-Based Medical Systems (CBMS),,,,,,,,,,,,,,, 9JVZHKC9,journalArticle,2018,"Luo, Yu; Iyengar, Garud; Venkatasubramanian, Venkat",Social Influence Makes Self-Interested Crowds Smarter: An Optimal Control Perspective,IEEE Transactions on Computational Social Systems,,2329-924X,10.1109/TCSS.2017.2780270,http://ieeexplore.ieee.org/document/8252783/,,2018-03,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,200-209,,1,5,,,Social Influence Makes Self-Interested Crowds Smarter,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, B85F32EM,conferencePaper,2014,"Hemmati, Azadeh; Chung, Kon Shing Kenneth",Social networks and quality of life: The national health interview survey,2014 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining (ASONAM 2014),978-1-4799-5877-1,,10.1109/ASONAM.2014.6921644,http://ieeexplore.ieee.org/document/6921644/,,2014-08,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,572-579,,,,,,Social networks and quality of life,,,,,IEEE,China,,,,,,Crossref,,,,,,cancer; quality of life; social network; social support; structure; egocentric network; ties; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2014 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining (ASONAM),,,,,,,,,,,,,,, 75RPA6Z8,conferencePaper,2012,"Pizzi, Nick J.",Soft computing and infectious disease modeling: A review and prescription,2012 Annual Meeting of the North American Fuzzy Information Processing Society (NAFIPS),978-1-4673-2338-3 978-1-4673-2336-9 978-1-4673-2337-6,,10.1109/NAFIPS.2012.6290988,http://ieeexplore.ieee.org/document/6290988/,,2012-08,21/11/2018 11:56,14/04/2020 08:35,21/11/2018 11:56,01-Jun,,,,,,Soft computing and infectious disease modeling,,,,,IEEE,"Berkeley, CA, USA",,,,,,Crossref,,,,,,00; 100; 120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NAFIPS 2012 - 2012 Annual Meeting of the North American Fuzzy Information Processing Society,,,,,,,,,,,,,,, 9FZMNV35,conferencePaper,2016,"Abeykoon, Chamil",Soft sensing of melt temperature in polymer extrusion,2016 European Control Conference (ECC),978-1-5090-2591-6,,10.1109/ECC.2016.7810308,http://ieeexplore.ieee.org/document/7810308/,,2016-06,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,340-345,,,,,,,,,,,IEEE,"Aalborg, Denmark",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 European Control Conference (ECC),,,,,,,,,,,,,,, 8P6AQHGW,conferencePaper,2012,"Ke, Wei; Liu, Zhiming",Software Engineering in Public Health: Opportunities and Challenges,2012 International Conference on Computer Distributed Control and Intelligent Environmental Monitoring,978-1-4673-0458-0 978-0-7695-4639-1,,10.1109/CDCIEM.2012.155,http://ieeexplore.ieee.org/document/6178484/,,2012-03,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,630-637,,,,,,Software Engineering in Public Health,,,,,IEEE,"Zhangjiajie, Hunan, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 International Conference on Computer Distributed Control and Intelligent Environmental Monitoring (CDCIEM),,,,,,,,,,,,,,, D5FGNYVR,conferencePaper,2014,"Chraibi, Abdelahad; Kharraja, Said; Osman, Ibrahim H.; Elbeqqali, Omar",Solving operating theater facility layout problem using a Multi-Agent system,"2014 International Conference on Control, Decision and Information Technologies (CoDIT)",978-1-4799-6773-5,,10.1109/CoDIT.2014.6996894,http://ieeexplore.ieee.org/document/6996894/,"Operating Theater Layout Problem (OTLP) has a great impact on the productivity and the efficiency of the health process. While solving OTLP, Real-life Operating Theater (OT) sizes are larger than exact methods capacity, this lead to explore other methods as heuristics, metaheuristics or parallel treatment looking for approximate solutions. In this paper we developed a novel approach using a Multi-Agent (MA) Decision Making System (DMS) based on Mixed Integer Linear Programming (MILP) for large-sized OTLP with objective of minimizing total traveling costs. The DMS generates exact solutions in reasonable time and gives the final OT layout in a graphic interface.",2014-11,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,207-212,,,,,,,,,,,IEEE,"Metz, France",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2014 International Conference on Control, Decision and Information Technologies (CoDIT)",,,,,,,,,,,,,,, 6K6MBTXH,conferencePaper,2017,"Thaxton, Sherry; Chen, Maijinn; Hsiang, Simon; Lim, Churlzu; Meyers, Jerry; Wald, Sam",Spacecraft Optimization Layout and Volume (SOLV): Development of a model to assess habitable volume,2017 IEEE Aerospace Conference,978-1-5090-1613-6,,10.1109/AERO.2017.7943592,http://ieeexplore.ieee.org/document/7943592/,,2017-03,21/11/2018 11:56,14/04/2020 08:35,21/11/2018 11:56,Jan-16,,,,,,Spacecraft Optimization Layout and Volume (SOLV),,,,,IEEE,"Big Sky, MT, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 IEEE Aerospace Conference,,,,,,,,,,,,,,, P6XXTGWS,conferencePaper,2012,"Pourhomayoun, M.; Zhanpeng Jin; Fowler, M.",Spatial sparsity based indoor localization in wireless sensor network for assistive healthcare,2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society,978-1-4577-1787-1 978-1-4244-4119-8,,10.1109/EMBC.2012.6346769,http://ieeexplore.ieee.org/document/6346769/,,2012-08,21/11/2018 11:56,14/04/2020 08:35,21/11/2018 11:56,3696-3699,,,,,,,,,,,IEEE,"San Diego, CA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC),,,,,,,,,,,,,,, 8ITQ4IA7,conferencePaper,2017,"Venkatramanan, Srinivasan; Chen, Jiangzhuo; Gupta, Sandeep; Lewis, Bryan; Marathe, Madhav; Mortveit, Henning; Vullikanti, Anil",Spatio-Temporal Optimization of Seasonal Vaccination Using a Metapopulation Model of Influenza,2017 IEEE International Conference on Healthcare Informatics (ICHI),978-1-5090-4881-6,,10.1109/ICHI.2017.83,http://ieeexplore.ieee.org/document/8031141/,"Prophylactic interventions such as vaccine allocation are one of the most effective public health policy planning tools. The supply of vaccines is limited, and an importantproblem is when and how to allocate the available vaccination supply, referred to as the Vaccine Allocation Problem. The spread of epidemics is modeled by the SEIR process, which has a very complex dynamics, and depends on human contacts and mobility. This makes the design of efficient solutions tovaccine allocation problem to minimize the number of infections a very challenging problem. In particular, this requires good models for human mobility, and optimization tools for vaccine allocation.In this paper, we study the vaccine allocation problem in the context of seasonal Influenza spread inthe United States. We develop a novel national scale flu model that integrate both short andlong distance travel, which are known to be important determinants of the spread of Influenza. We also design a greedy algorithm for allocating the vaccine supply at a county level. Our results show significant improvement over the current baseline, whichinvolves allocating vaccines based on the state population.",2017-08,21/11/2018 11:56,14/04/2020 08:35,21/11/2018 11:56,134-143,,,,,,,,,,,IEEE,"Park City, UT, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 IEEE International Conference on Healthcare Informatics (ICHI),,,,,,,,,,,,,,, NA7NPFFF,journalArticle,2014,"Li, Kongjing; Tian, Gui Yun; Cheng, Liang; Yin, Aijun; Cao, Wenping; Crichton, Stuart",State Detection of Bond Wires in IGBT Modules Using Eddy Current Pulsed Thermography,IEEE Transactions on Power Electronics,,"0885-8993, 1941-0107",10.1109/TPEL.2013.2288334,http://ieeexplore.ieee.org/document/6654355/,,2014-09,21/11/2018 11:56,14/04/2020 08:34,21/11/2018 11:56,5000-5009,,9,29,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WLIYKKJ9,journalArticle,2017,"Wang, Dong; Tsui, Kwok-Leung",Statistical Modeling of Bearing Degradation Signals,IEEE Transactions on Reliability,,"0018-9529, 1558-1721",10.1109/TR.2017.2739126,http://ieeexplore.ieee.org/document/8023771/,,2017-12,21/11/2018 11:56,14/04/2020 08:35,21/11/2018 11:56,1331-1344,,4,66,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ED2DLRDJ,journalArticle,2016,"Lin, Shih-Chun; Chen, Kwang-Cheng",Statistical QoS Control of Network Coded Multipath Routing in Large Cognitive Machine-to-Machine Networks,IEEE Internet of Things Journal,,2327-4662,10.1109/JIOT.2015.2478435,http://ieeexplore.ieee.org/document/7264970/,,2016-08,21/11/2018 11:57,14/04/2020 08:34,21/11/2018 11:57,619-627,,4,3,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, W6SGD3IM,conferencePaper,2017,"Yates, Roy D.; Kaul, Sanjit K.",Status updates over unreliable multiaccess channels,2017 IEEE International Symposium on Information Theory (ISIT),978-1-5090-4096-4,,10.1109/ISIT.2017.8006544,http://ieeexplore.ieee.org/document/8006544/,,2017-06,21/11/2018 11:57,14/04/2020 08:35,21/11/2018 11:57,331-335,,,,,,,,,,,IEEE,"Aachen, Germany",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 IEEE International Symposium on Information Theory (ISIT),,,,,,,,,,,,,,, XQ9TGSM7,journalArticle,2016,"Alghassi, Alireza; Perinpanayagam, Suresh; Samie, Mohammad",Stochastic RUL Calculation Enhanced With TDNN-Based IGBT Failure Modeling,IEEE Transactions on Reliability,,"0018-9529, 1558-1721",10.1109/TR.2015.2499960,http://ieeexplore.ieee.org/document/7350250/,,2016-06,21/11/2018 11:57,14/04/2020 08:34,21/11/2018 11:57,558-573,,2,65,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RRNGFTZP,conferencePaper,2012,"Shi, Arthur; Yu, Xiao-Hua",Structural damage detection using artificial neural networks and wavelet transform,2012 IEEE International Conference on Computational Intelligence for Measurement Systems and Applications (CIMSA) Proceedings,978-1-4577-1779-6 978-1-4577-1778-9 978-1-4577-1777-2,,10.1109/CIMSA.2012.6269593,http://ieeexplore.ieee.org/document/6269593/,,2012-07,21/11/2018 11:57,14/04/2020 08:35,21/11/2018 11:57,07-Nov,,,,,,,,,,,IEEE,"Tianjin, China",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 IEEE International Conference on Computational Intelligence for Measurement Systems and Applications (CIMSA),,,,,,,,,,,,,,, YN9BCYYK,conferencePaper,2014,"Ruan, Jiabiao; Ho, Siu Chun Michael; Patil, Devendra; Song, Gangbing",Structural health monitoring of wind turbine blade using piezoceremic based active sensing and impedance sensing,"Proceedings of the 11th IEEE International Conference on Networking, Sensing and Control",978-1-4799-3106-4,,10.1109/ICNSC.2014.6819704,http://ieeexplore.ieee.org/document/6819704/,,2014-04,21/11/2018 11:57,14/04/2020 08:35,21/11/2018 11:57,661-666,,,,,,,,,,,IEEE,"Miami, FL, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2014 IEEE 11th International Conference on Networking, Sensing and Control (ICNSC)",,,,,,,,,,,,,,, PJASTD44,conferencePaper,2017,"Miskiewicz, Mikolaj; Pyrzowski, Lukasz; Wilde, Krzysztof",Structural Health Monitoring System for Suspension Footbridge,2017 Baltic Geodetic Congress (BGC Geomatics),978-1-5090-6040-5,,10.1109/BGC.Geomatics.2017.8,http://ieeexplore.ieee.org/document/8071495/,,2017-06,21/11/2018 11:57,14/04/2020 08:34,21/11/2018 11:57,321-325,,,,,,,,,,,IEEE,"Gdansk, Poland",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 Baltic Geodetic Congress (BGC Geomatics),,,,,,,,,,,,,,, 99T7EZFX,conferencePaper,2011,"Sun, Peng; Guo, Xin",Structural Health Monitoring via Dynamic Visualization,2011 Seventh International Conference on Computational Intelligence and Security,978-1-4577-2008-6 978-0-7695-4584-4,,10.1109/CIS.2011.346,http://ieeexplore.ieee.org/document/6128387/,,2011-12,21/11/2018 11:57,14/04/2020 08:35,21/11/2018 11:57,1546-1548,,,,,,,,,,,IEEE,"Sanya, Hainan, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2011 Seventh International Conference on Computational Intelligence and Security (CIS),,,,,,,,,,,,,,, Y5IWT65W,conferencePaper,2015,"AL-Smadi, Yahia M.; Albalushi, Khalid S.",Structural health prediction model for oil well casing,2015 International Mediterranean Gas and Oil Conference (MedGO),978-1-4799-8572-2,,10.1109/MedGO.2015.7330333,http://ieeexplore.ieee.org/lpdocs/epic03/wrapper.htm?arnumber=7330333,,2015-04,21/11/2018 11:57,14/04/2020 08:34,21/11/2018 11:57,01-Mar,,,,,,,,,,,IEEE,"Mechref, Lebanon",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 International Mediterranean Gas and Oil Conference (MedGO),,,,,,,,,,,,,,, DNWGEC4B,conferencePaper,2012,Tao Xu; Zhihong Liu; Sheng Wang; Lei Liu,Study and practice on the construction of demonstration area on power supply's high-reliability in Chongqing,2012 China International Conference on Electricity Distribution,978-1-4673-6064-7 978-1-4673-6065-4 978-1-4673-6063-0,,10.1109/CICED.2012.6508529,http://ieeexplore.ieee.org/document/6508529/,,2012-09,21/11/2018 11:57,14/04/2020 08:35,21/11/2018 11:57,01-Apr,,,,,,,,,,,IEEE,"Shanghai, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 China International Conference on Electricity Distribution (CICED),,,,,,,,,,,,,,, 2YJES7WG,conferencePaper,2016,"Cheng, Yao; Gao, Xin; Gao, Tianyi; Ren, Zelin",Study on support vector machine based quality prediction of complex mechatronic systems,2016 Seventh International Conference on Intelligent Control and Information Processing (ICICIP),978-1-5090-2155-0,,10.1109/ICICIP.2016.7885898,http://ieeexplore.ieee.org/document/7885898/,,2016-12,21/11/2018 11:57,14/04/2020 08:34,21/11/2018 11:57,179-184,,,,,,,,,,,IEEE,"Siem Reap, Cambodia",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 Seventh International Conference on Intelligent Control and Information Processing (ICICIP),,,,,,,,,,,,,,, Q7PD5GFJ,conferencePaper,2011,"Yanushkevich, S.N.",Synthetic Biometrics for Training Users of Biometric and Biomedical Systems,2011 International Conference on Cyberworlds,978-1-4577-1453-5 978-0-7695-4467-0,,10.1109/CW.2011.47,http://ieeexplore.ieee.org/document/6079339/,,2011-10,21/11/2018 11:57,14/04/2020 08:35,21/11/2018 11:57,05-Aug,,,,,,,,,,,IEEE,"Calgary, AB, Canada",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2011 International Conference on Cyberworlds (CW),,,,,,,,,,,,,,, MUVYAHDN,conferencePaper,2014,"Terrasson, Guillaume; Llaria, Alvaro; Briand, Renaud",System level dimensioning of low power biomedical Body Sensor Networks,2014 IEEE Faible Tension Faible Consommation,978-1-4799-3773-8,,10.1109/FTFC.2014.6828621,http://ieeexplore.ieee.org/document/6828621/,,2014-05,21/11/2018 11:57,14/04/2020 08:35,21/11/2018 11:57,01-Apr,,,,,,,,,,,IEEE,"Monaco, Monaco",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2014 IEEE Faible Tension Faible Consommation (FTFC),,,,,,,,,,,,,,, Q8M989V2,conferencePaper,2008,"Sloane, Elliot; Gehlot, Vijay; Way, Thomas; Beck, Robert",System of Systems Issues for the 2008 U. S. National Healthcare Information Network Remote Patient Monitoring Requirements,2008 2nd Annual IEEE Systems Conference,978-1-4244-2149-7 978-1-4244-2150-3,,10.1109/SYSTEMS.2008.4519018,http://ieeexplore.ieee.org/document/4519018/,,2008-04,21/11/2018 11:57,14/04/2020 08:35,21/11/2018 11:57,01-May,,,,,,,,,,,IEEE,"Montreal, QC, Canada",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2008 2nd Annual IEEE Systems Conference,,,,,,,,,,,,,,, B77NF8XJ,conferencePaper,2012,"Nakajima, Hiroshi; Shiga, Toshikazu; Hata, Yutaka",Systems Health Care the aspect of home and medical care,"2012 IEEE International Conference on Systems, Man, and Cybernetics (SMC)",978-1-4673-1714-6 978-1-4673-1713-9 978-1-4673-1712-2,,10.1109/ICSMC.2012.6378141,http://ieeexplore.ieee.org/document/6378141/,,2012-10,21/11/2018 11:57,14/04/2020 08:35,21/11/2018 11:57,2616-2621,,,,,,,,,,,IEEE,"Seoul, Korea (South)",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2012 IEEE International Conference on Systems, Man and Cybernetics - SMC",,,,,,,,,,,,,,, UYWW3EHE,conferencePaper,2012,"Nakajima, Hiroshi; Shiga, Toshikazu; Hata, Yutaka",Systems Health Care: Coevolutionary Integration of Smart Devices and Smart Services,2012 Annual SRII Global Conference,978-1-4673-2318-5 978-0-7695-4770-1,,10.1109/SRII.2012.33,http://ieeexplore.ieee.org/document/6311000/,,2012-07,21/11/2018 11:57,14/04/2020 08:35,21/11/2018 11:57,231-236,,,,,,Systems Health Care,,,,,IEEE,"San Jose, CA, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 Annual SRII Global Conference (SRII),,,,,,,,,,,,,,, YSIHAH55,conferencePaper,2008,"Sloane, Elliot",Systems of Systems (SoSE) Engineering for the 21st Century Healthcare Enterprise,2008 2nd Annual IEEE Systems Conference,978-1-4244-2149-7 978-1-4244-2150-3,,10.1109/SYSTEMS.2008.4519013,http://ieeexplore.ieee.org/document/4519013/,,2008-04,21/11/2018 11:57,14/04/2020 08:35,21/11/2018 11:57,01-Apr,,,,,,,,,,,IEEE,"Montreal, QC, Canada",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2008 2nd Annual IEEE Systems Conference,,,,,,,,,,,,,,, UIHZUJJK,journalArticle,2013,"Manukyan, Narine; Eppstein, Margaret J.; Horbar, Jeffrey D.",Team Learning for Healthcare Quality Improvement,IEEE Access,,2169-3536,10.1109/ACCESS.2013.2280086,http://ieeexplore.ieee.org/document/6587516/,,2013,21/11/2018 11:57,14/04/2020 08:34,21/11/2018 11:57,545-557,,,1,,,,,,,,,,,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FRHWZUT4,journalArticle,2017,"Liu, Zhenbao; Huang, Jinxin; Bu, Shuhui; Han, Junwei; Tang, Xiaojun; Li, Xuelong",Template Deformation-Based 3-D Reconstruction of Full Human Body Scans From Low-Cost Depth Cameras,IEEE Transactions on Cybernetics,,"2168-2267, 2168-2275",10.1109/TCYB.2016.2524406,http://ieeexplore.ieee.org/document/7416183/,,2017-03,21/11/2018 11:57,14/04/2020 08:34,21/11/2018 11:57,695-708,,3,47,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, E7NHTET5,conferencePaper,2012,"Luangkesorn, K Louis; Bountourelis, Theologos; Schaefer, Andrew; Nabors, Spencer; Clermont, Gilles",The case against utilization: Deceptive performance measures in inpatient care capacity models,Proceedings Title: Proceedings of the 2012 Winter Simulation Conference (WSC),978-1-4673-4782-2 978-1-4673-4779-2 978-1-4673-4780-8 978-1-4673-4781-5,,10.1109/WSC.2012.6465104,http://ieeexplore.ieee.org/document/6465104/,,2012-12,21/11/2018 11:57,14/04/2020 08:34,21/11/2018 11:57,01-Dec,,,,,,The case against utilization,,,,,IEEE,"Berlin, Germany",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 Winter Simulation Conference - (WSC 2012),,,,,,,,,,,,,,, 3UFS896J,conferencePaper,2017,"He, Saike; Zheng, Xiaolong; Zeng, Daniel",The dynamics of health sentiments with competitive interactions in social media,2017 IEEE International Conference on Intelligence and Security Informatics (ISI),978-1-5090-6727-5,,10.1109/ISI.2017.8004882,http://ieeexplore.ieee.org/document/8004882/,,2017-07,21/11/2018 11:57,14/04/2020 08:34,21/11/2018 11:57,101-106,,,,,,,,,,,IEEE,"Beijing, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 IEEE International Conference on Intelligence and Security Informatics (ISI),,,,,,,,,,,,,,, VU8SI2UM,conferencePaper,2017,"Leontiadis, Ilias; Serra, Joan; Finamore, Alessandro; Dimopoulos, Giorgos; Papagiannaki, Konstantina","The Good, the Bad, and the KPIs: How to Combine Performance Metrics to Better Capture Underperforming Sectors in Mobile Networks",2017 IEEE 33rd International Conference on Data Engineering (ICDE),978-1-5090-6543-1,,10.1109/ICDE.2017.89,http://ieeexplore.ieee.org/document/7929986/,,2017-04,21/11/2018 11:57,14/04/2020 08:34,21/11/2018 11:57,297-308,,,,,,"The Good, the Bad, and the KPIs",,,,,IEEE,"San Diego, CA, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 IEEE 33rd International Conference on Data Engineering (ICDE),,,,,,,,,,,,,,, 6CJXB4TD,conferencePaper,2016,"Dzubay, David P.; Perez, Eduardo",The impact of system factors on patient perceptions of quality of care,2016 Winter Simulation Conference (WSC),978-1-5090-4486-3,,10.1109/WSC.2016.7822259,http://ieeexplore.ieee.org/document/7822259/,"The Hospital Value-Based Purchasing (VBP) Program is a Center for Medicare and Medicaid Services (CMS) initiative that rewards hospitals with incentive payments for the quality of care they provide to patients with Medicare instead of the quantity of procedures they perform. Although the VBP program has direct implications toward both patients and hospitals, no research has been reported in the literature addressing how hospitals can enhance patients' experience of care. This research uses systems modeling to improve the patient experience of care considering the eight dimensions in the Hospital VBP. A case study is presented that considers three intensive care units from a hospital located in central Texas. The simulation results show that strategies such as having a quick patient discharge process greatly benefit the hospital in terms of how patients perceive quality of care as measured by the Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) survey.",2016-12,21/11/2018 11:57,14/04/2020 08:34,21/11/2018 11:57,2169-2179,,,,,,,,,,,IEEE,"Washington, DC, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 Winter Simulation Conference (WSC),,,,,,,,,,,,,,, SHIUFAWB,conferencePaper,2016,Xue Pengbo; Jin Guodong; Lu Libin; Tan Lining; Ning Jigan,The key technology and simulation of UAV flight monitoring system,"2016 IEEE Advanced Information Management, Communicates, Electronic and Automation Control Conference (IMCEC)",978-1-4673-9613-4,,10.1109/IMCEC.2016.7867478,http://ieeexplore.ieee.org/document/7867478/,,2016-10,21/11/2018 11:57,14/04/2020 08:35,21/11/2018 11:57,1551-1557,,,,,,,,,,,IEEE,"Xi'an, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2016 IEEE Advanced Information Management, Communicates, Electronic and Automation Control Conference (IMCEC)",,,,,,,,,,,,,,, 2A4XCTC2,conferencePaper,2013,"Jing, Shenqi; Wang, Zhongmin; Liu, Yun; Kou, Jianqiu; Han, Shanqing",The Practice of Hospital Operation Management in the Era of New Healthcare Reform,2013 International Conference on Information Technology and Applications,978-1-4799-2877-4 978-1-4799-2876-7,,10.1109/ITA.2013.52,http://ieeexplore.ieee.org/document/6709968/,,2013-11,21/11/2018 11:57,14/04/2020 08:34,21/11/2018 11:57,197-199,,,,,,,,,,,IEEE,"Chengdu, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2013 International Conference on Information Technology and Applications (ITA),,,,,,,,,,,,,,, 45YWDK2I,conferencePaper,2010,"Akhondi, Mohammad reza; Talevski, Alex; Carlsen, Simon; Petersen, Stig",The role of wireless sensor networks (WSNs) in industrial oil and gas condition monitoring,4th IEEE International Conference on Digital Ecosystems and Technologies,978-1-4244-5551-5,,10.1109/DEST.2010.5610584,http://ieeexplore.ieee.org/document/5610584/,,2010-04,21/11/2018 11:57,14/04/2020 08:34,21/11/2018 11:57,618-623,,,,,,,,,,,IEEE,"Dubai, United Arab Emirates",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2010 4th IEEE International Conference on Digital Ecosystems and Technologies (DEST),,,,,,,,,,,,,,, 96GTY52L,conferencePaper,2010,Nai-Bin Hsu,The Routing of Healthcare Applications in MPLS Networks,2010 Fourth International Conference on Genetic and Evolutionary Computing,978-1-4244-8891-9,,10.1109/ICGEC.2010.195,http://ieeexplore.ieee.org/document/5715545/,,2010-12,21/11/2018 11:57,14/04/2020 08:35,21/11/2018 11:57,771-774,,,,,,,,,,,IEEE,Shenzhen,,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2010 Fourth International Conference on Genetic and Evolutionary Computing (ICGEC 2010),,,,,,,,,,,,,,, 3AEQCQBC,conferencePaper,2017,"Kaewchan, Thapanat; Wangrakdiskul, Ubolrat",The six sigma approach for photodiode shear strength bonding improvment of head gimbal assembly component,2017 15th International Conference on ICT and Knowledge Engineering (ICT&KE),978-1-5386-2115-8 978-1-5386-2117-2,,10.1109/ICTKE.2017.8259625,http://ieeexplore.ieee.org/document/8259625/,,2017-11,21/11/2018 11:57,14/04/2020 08:34,21/11/2018 11:57,01-May,,,,,,,,,,,IEEE,Bangkok,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 15th International Conference on ICT and Knowledge Engineering (ICT&KE),,,,,,,,,,,,,,, UMD5ZL43,conferencePaper,2018,"Ventura dos Santos Serralheiro, Ana Raquel; Morais, Georgina","The SL attachment, the integrated management systems and the challenges for internal auditing: Companies in the central region — Case study",2018 13th Iberian Conference on Information Systems and Technologies (CISTI),978-989-98434-8-6,,10.23919/CISTI.2018.8399471,https://ieeexplore.ieee.org/document/8399471/,,2018-06,21/11/2018 11:57,14/04/2020 08:35,21/11/2018 11:57,01-Jul,,,,,,"The SL attachment, the integrated management systems and the challenges for internal auditing",,,,,IEEE,Caceres,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2018 13th Iberian Conference on Information Systems and Technologies (CISTI),,,,,,,,,,,,,,, WK7JPEIS,journalArticle,2018,"Wang, Haonan; Dong, Linxi; Wei, Wei; Zhao, Wen-Sheng; Xu, Kuiwen; Wang, Gaofeng",The WSN Monitoring System for Large Outdoor Advertising Boards Based on ZigBee and MEMS Sensor,IEEE Sensors Journal,,"1530-437X, 1558-1748, 2379-9153",10.1109/JSEN.2017.2770324,http://ieeexplore.ieee.org/document/8098652/,,01/02/2018,21/11/2018 11:57,14/04/2020 08:35,21/11/2018 11:57,1314-1323,,3,18,,,,,,,,,,,,,,,Crossref,,,,,,00; 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Annual International Conference of the IEEE Engineering in Medicine and Biology Society,,,,,,,,,,,,,,, EHBADG4D,conferencePaper,2015,"Yin, Jie; Zhang, Qing; Karunanithi, Mohan",Unsupervised daily routine and activity discovery in smart homes,2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC),978-1-4244-9271-8,,10.1109/EMBC.2015.7319636,https://ieeexplore.ieee.org/document/7319636/,,2015-08,21/11/2018 11:58,14/04/2020 08:35,21/11/2018 11:58,5497-5500,,,,,,,,,,,IEEE,Milan,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC),,,,,,,,,,,,,,, L46L28MR,conferencePaper,2016,"Dukes, Lauren Cairco; Meehan, Nancy; Hodges, Larry F.",Usability Evaluation of a Pediatric Virtual Patient Creation Tool,2016 IEEE International Conference on Healthcare Informatics (ICHI),978-1-5090-6117-4,,10.1109/ICHI.2016.20,http://ieeexplore.ieee.org/document/7776336/,,2016-10,21/11/2018 11:58,14/04/2020 08:34,21/11/2018 11:58,118-128,,,,,,,,,,,IEEE,"Chicago, IL, USA",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 IEEE International Conference on Healthcare Informatics (ICHI),,,,,,,,,,,,,,, XD9BE6JS,journalArticle,2017,"Whitehead, N. Peter; Scherer, William T.; Smith, Michael C.",Use of Natural Language Processing to Discover Evidence of Systems Thinking,IEEE Systems Journal,,"1932-8184, 1937-9234, 2373-7816",10.1109/JSYST.2015.2426651,http://ieeexplore.ieee.org/document/7112126/,,2017-12,21/11/2018 11:58,14/04/2020 08:35,21/11/2018 11:58,2140-2149,,4,11,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8DQZE9DJ,conferencePaper,2016,"Crossley, Carrie; Fanfarelli, Joseph R.; McDaniel, Rudy",User experience design considerations for healthcare games and applications,2016 IEEE International Conference on Serious Games and Applications for Health (SeGAH),978-1-5090-2210-6,,10.1109/SeGAH.2016.7586264,http://ieeexplore.ieee.org/document/7586264/,,2016-05,21/11/2018 11:58,14/04/2020 08:34,21/11/2018 11:58,01-Aug,,,,,,,,,,,IEEE,"Orlando, FL, USA",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2016 IEEE International Conference on Serious Games and Applications for Health (SeGAH),,,,,,,,,,,,,,, 7VU3EAG7,conferencePaper,2009,"Cable, Dustin; Seok, Julius; Alemayehu, Robel; Foster, Alexander Thomas",Using a systems approach in managing and evaluating water and sanitation development projects,2009 Systems and Information Engineering Design Symposium,978-1-4244-4531-8,,10.1109/SIEDS.2009.5166170,http://ieeexplore.ieee.org/document/5166170/,,2009-04,21/11/2018 11:58,14/04/2020 08:34,21/11/2018 11:58,147-152,,,,,,,,,,,IEEE,"Charlottesville, VA, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2009 Systems and Information Engineering Design Symposium (SIEDS),,,,,,,,,,,,,,, I5RAKY2B,conferencePaper,2008,"Luculescu, M. C.; Lache, S.",Using artificial neural networks in a Computer Aided Diagnosis system for Macular diseases,"2008 IEEE International Conference on Automation, Quality and Testing, Robotics",978-1-4244-2576-1,,10.1109/AQTR.2008.4588899,http://ieeexplore.ieee.org/document/4588899/,,2008,21/11/2018 11:58,14/04/2020 08:34,21/11/2018 11:58,143-148,,,,,,,,,,,IEEE,"Cluj-Napoca, Romania",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2008 IEEE International Conference on Automation, Quality and Testing, Robotics",,,,,,,,,,,,,,, 57KPSDSY,conferencePaper,2017,"Aydin, Olgun; Guldamlasioglu, Seren",Using LSTM networks to predict engine condition on large scale data processing framework,2017 4th International Conference on Electrical and Electronic Engineering (ICEEE),978-1-5090-6789-3,,10.1109/ICEEE2.2017.7935834,http://ieeexplore.ieee.org/document/7935834/,,2017-04,21/11/2018 11:58,14/04/2020 08:34,21/11/2018 11:58,281-285,,,,,,,,,,,IEEE,"Ankara, Turkey",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 4th International Conference on Electrical and Electronic Engineering (ICEEE),,,,,,,,,,,,,,, ZGGMHRTT,conferencePaper,2011,"Jazouli, Taoufik; Sandborn, Peter",Using PHM to meet availability-based contracting requirements,2011 IEEE Conference on Prognostics and Health Management,978-1-4244-9828-4,,10.1109/ICPHM.2011.6024317,http://ieeexplore.ieee.org/document/6024317/,,2011-06,21/11/2018 11:58,14/04/2020 08:34,21/11/2018 11:58,01-Dec,,,,,,,,,,,IEEE,"Denver, CO, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2011 IEEE Conference on Prognostics and Health Management (PHM),,,,,,,,,,,,,,, CAKKSEZS,conferencePaper,2013,"Ye, Xiang; Zhou, Lihui",Using SCADA Data Fusion by Swarm Intelligence for Wind Turbine Condition Monitoring,2013 Fourth Global Congress on Intelligent Systems,978-1-4799-2886-6 978-1-4799-2885-9,,10.1109/GCIS.2013.40,http://ieeexplore.ieee.org/document/6805937/,,2013-12,21/11/2018 11:58,14/04/2020 08:35,21/11/2018 11:58,210-215,,,,,,,,,,,IEEE,"Hong Kong, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2013 Fourth Global Congress on Intelligent Systems (GCIS),,,,,,,,,,,,,,, YEZHDM8D,conferencePaper,2015,"Alali, Jawahir Abdalla; Alalili, Mariam Salim Khalfan; Bashir, Hamdi; Dweiri, Fikri; Al-Kubaisi, Amal Yousuf",Using statistical process control charts for monitoring birth weight at a national level,2015 International Conference on Industrial Engineering and Operations Management (IEOM),978-1-4799-6065-1,,10.1109/IEOM.2015.7093838,http://ieeexplore.ieee.org/document/7093838/,,2015-03,21/11/2018 11:58,14/04/2020 08:34,21/11/2018 11:58,01-May,,,,,,,,,,,IEEE,Dubai,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 International Conference on Industrial Engineering and Operations Management (IEOM),,,,,,,,,,,,,,, 3GVJYUUA,conferencePaper,2011,"Wang, Feng; Liu, Jiangchuan; Wang, Dan",Utilizing elevator for wireless sensor data collection in high-rise structure monitoring,2011 IEEE Nineteenth IEEE International Workshop on Quality of Service,978-1-4577-0104-7,,10.1109/IWQOS.2011.5931350,http://ieeexplore.ieee.org/document/5931350/,,2011-06,21/11/2018 11:58,14/04/2020 08:35,21/11/2018 11:58,01-Sep,,,,,,,,,,,IEEE,"San Jose, CA, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2011 IEEE 19th International Workshop on Quality of Service (IWQoS),,,,,,,,,,,,,,, J6PDIUE9,conferencePaper,2017,"Abdulrahman, R. K.; Zangana, M. H. S.; Ali, K. S.; Slagle, J. C.",Utilizing mixed amines in gas sweetening process: A Kirkuk field case study and simulation,2017 International Conference on Environmental Impacts of the Oil and Gas Industries: Kurdistan Region of Iraq as a Case Study (EIOGI),978-1-5090-3062-0,,10.1109/EIOGI.2017.8267616,http://ieeexplore.ieee.org/document/8267616/,,2017-04,21/11/2018 11:58,14/04/2020 08:34,21/11/2018 11:58,05-Aug,,,,,,Utilizing mixed amines in gas sweetening process,,,,,IEEE,"Koya-Erbil, Iraq",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 International Conference on Environmental Impacts of the Oil and Gas Industries: Kurdistan Region of Iraq as a Case Study (EIOGI),,,,,,,,,,,,,,, 5J7ZCP8B,conferencePaper,2017,"Alvarez, Jean Kyle; Sutjipto, Sheila; Kodagoda, Sarath",Validated ground penetrating radar simulation model for estimating rebar location in infrastructure monitoring,2017 12th IEEE Conference on Industrial Electronics and Applications (ICIEA),978-1-5090-6161-7,,10.1109/ICIEA.2017.8283069,http://ieeexplore.ieee.org/document/8283069/,,2017-06,21/11/2018 11:58,14/04/2020 08:34,21/11/2018 11:58,1460-1465,,,,,,,,,,,IEEE,Siem Reap,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2017 12th IEEE Conference on Industrial Electronics and Applications (ICIEA),,,,,,,,,,,,,,, W7VAPIX4,conferencePaper,2012,"Trindade, Andreia; Rodrigues, Pedro; Perkins, Amy E.; Miller, Michael A.; Narayanan, Manoj; Griesmer, Jerome; Tung, Chi-Hua; Zhang, Bin; Shao, Lingxiong; Laurence, Thomas; Solf, Torsten; Wieczorek, Herfried",Validation of GATE Monte Carlo simulations of the Philips GEMINI TF and TruFlight Select PET/CT scanners based on NEMA NU2 standards,2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC),978-1-4673-2030-6 978-1-4673-2028-3 978-1-4673-2029-0,,10.1109/NSSMIC.2012.6551582,http://ieeexplore.ieee.org/document/6551582/,,2012-10,21/11/2018 11:58,14/04/2020 08:35,21/11/2018 11:58,2546-2549,,,,,,,,,,,IEEE,"Anaheim, CA, USA",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2012 IEEE Nuclear Science Symposium and Medical Imaging Conference (2012 NSS/MIC),,,,,,,,,,,,,,, 963CA4BR,journalArticle,2012,"Markarian, G.; Mihaylova, L.; Tsitserov, D. V.; Zvikhachevskaya, A.",Video Distribution Techniques Over WiMAX Networks for m-Health Applications,IEEE Transactions on Information Technology in Biomedicine,,"1089-7771, 1558-0032",10.1109/TITB.2011.2174157,http://ieeexplore.ieee.org/document/6064891/,,2012-01,21/11/2018 11:58,14/04/2020 08:34,21/11/2018 11:58,24-30,,1,16,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YKUJRIUC,journalArticle,2002,"Prado, M.; Roa, L.; Reina-Tosina, J.; Palma, A.; Milan, J.A.",Virtual center for renal support: technological approach to patient physiological image,IEEE Transactions on Biomedical Engineering,,0018-9294,10.1109/TBME.2002.805454,http://ieeexplore.ieee.org/document/1159134/,,2002-12,21/11/2018 11:58,14/04/2020 08:35,21/11/2018 11:58,1420-1430,,12,49,,,Virtual center for renal support,,,,,,,en,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, SWN965KH,journalArticle,2012,"Ivanov, S.; Foley, C.; Balasubramaniam, S.; Botvich, D.",Virtual Groups for Patient WBAN Monitoring in Medical Environments,IEEE Transactions on Biomedical Engineering,,"0018-9294, 1558-2531",10.1109/TBME.2012.2208110,http://ieeexplore.ieee.org/document/6237515/,,2012-11,21/11/2018 11:58,14/04/2020 08:34,21/11/2018 11:58,3238-3246,,11,59,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, L776SYFV,conferencePaper,2009,Hongwei Huo; Wei Shen; Youzhi Xu; Hongke Zhang,Virtual Hypercube Routing in wireless sensor networks for health care systems,2009 First International Conference on Future Information Networks,978-1-4244-5158-6,,10.1109/ICFIN.2009.5339574,http://ieeexplore.ieee.org/document/5339574/,,2009-10,21/11/2018 11:58,14/04/2020 08:34,21/11/2018 11:58,178-183,,,,,,,,,,,IEEE,"Beijing, China",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2009 First International Conference on Future Information Networks (ICFIN),,,,,,,,,,,,,,, C7NTRI2M,journalArticle,2012,"Yoo, T. S.; Bliss, D.; Lowekamp, B. C.; Chen, D. T.; Murphy, G. E.; Narayan, K.; Hartnell, L. M.; Thao Do; Subramaniam, S.",Visualizing Cells and Humans in 3D: Biomedical Image Analysis at Nanometer and Meter Scales,IEEE Computer Graphics and Applications,,0272-1716,10.1109/MCG.2012.68,http://ieeexplore.ieee.org/document/6226336/,,2012-09,21/11/2018 11:58,14/04/2020 08:35,21/11/2018 11:58,39-49,,5,32,,,Visualizing Cells and Humans in 3D,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HLIQZJWM,conferencePaper,2015,"Takama, Yasufumi; Sasaki, Wataru; Okumura, Takafumi; Yu, Chi-Chih; Chen, Lieu-Hen; Ishikawa, Hiroshi",Walking Route Recommendation System for Taking a Walk as Health Promotion,2015 IEEE/WIC/ACM International Conference on Web Intelligence and Intelligent Agent Technology (WI-IAT),978-1-4673-9618-9,,10.1109/WI-IAT.2015.218,http://ieeexplore.ieee.org/document/7396862/,,2015-12,21/11/2018 11:58,14/04/2020 08:35,21/11/2018 11:58,556-559,,,,,,,,,,,IEEE,"Singapore, Singapore",,,,,,Crossref,,,,,,00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2015 IEEE / WIC / ACM International Conference on Web Intelligence and Intelligent Agent Technology (WI-IAT),,,,,,,,,,,,,,, RJ3EK2BD,conferencePaper,2010,"McIlwraith, D; Pansiot, J; Guang-Zhong Yang",Wearable and ambient sensor fusion for the characterisation of human motion,2010 IEEE/RSJ International Conference on Intelligent Robots and Systems,978-1-4244-6674-0,,10.1109/IROS.2010.5650512,http://ieeexplore.ieee.org/document/5650512/,,2010-10,21/11/2018 11:58,14/04/2020 08:34,21/11/2018 11:58,5505-5510,,,,,,,,,,,IEEE,Taipei,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2010 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS 2010),,,,,,,,,,,,,,, EKK28V9B,journalArticle,2011,"Lee, Hyungho; Park, Kyung-Joon; Ko, Young-Bae; Choi, Chong-Ho",Wireless LAN with medical-grade QoS for e-healthcare,Journal of Communications and Networks,,1229-2370,10.1109/JCN.2011.6157414,http://ieeexplore.ieee.org/document/6157414/,,2011-04,21/11/2018 11:58,14/04/2020 08:34,21/11/2018 11:58,149-159,,2,13,,,,,,,,,,,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QKL2TIHM,conferencePaper,2013,"Zhang, Zhongwei; Hu, Xiaohu",ZigBee based wireless sensor networks and their use in medical and health care domain,2013 Seventh International Conference on Sensing Technology (ICST),978-1-4673-5222-2 978-1-4673-5220-8,,10.1109/ICSensT.2013.6727754,http://ieeexplore.ieee.org/document/6727754/,,2013-12,21/11/2018 11:58,14/04/2020 08:35,21/11/2018 11:58,756-761,,,,,,,,,,,IEEE,"Wellington, New Zealand",,,,,,Crossref,,,,,,00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2013 Seventh International Conference on Sensing Technology (ICST),,,,,,,,,,,,,,, 3DDMXBBR,journalArticle,2018,"Ho, Li-Ming; Schafferer, Christian; Lee, Jie-Min; Yeh, Chun-Yuan; Hsieh, Chi-Jung",Raising cigarette excise tax to reduce consumption in low-and middle-income countries of the Asia-Pacific region:a simulation of the anticipated health and taxation revenues impacts.,BMC public health,,1471-2458 1471-2458,10.1186/s12889-018-6096-z,,"BACKGROUND: According to the World Health Organization (WHO), 80% of the world's smokers live in low- and middle-income countries. Moreover, more than half of the world's smoking-addicted population resides in the Asia-Pacific region. The reduction of tobacco consumption has thus become one of the major social policies in the region. This study investigates the effects of price increases on cigarette consumption, tobacco tax revenues and reduction in smoking-caused mortality in 22 low-income as well as middle-income countries in the Asia-Pacific region. METHODS: Using panel data from the 1999-2015 Euromonitor International, the World Bank and the World Health Organization, we applied fixed effects regression models of panel data to estimate the elasticity of cigarette prices and to simulate the effect of price fluctuations. RESULTS: Cigarette price elasticity was the highest for countries with a per capita Gross National Income (GNI) above US$6000 (China and Malaysia), and considerably higher for other economies in the region. The administered simulation shows that with an average annual cigarette price increase of 9.51%, the average annual cigarette consumption would decrease by 3.56%, and the average annual tobacco tax revenue would increase by 16.20%. The number of averted smoking-attributable deaths (SADs) would be the highest in China, followed by Indonesia and India. In total, over 17.96 million lives could be saved by tax increases. CONCLUSION: Excise tax increases have a significant effect on the reduction of smoking prevalence and the number of averted smoking-attributable deaths. Middle- and upper-middle income countries would be most affected by high-taxation policies.",19/10/2018,26/11/2018 12:49,14/04/2020 08:34,,1187,,1,18,,BMC Public Health,,,,,,,,eng,,,,,,,PMID: 30340557 PMCID: PMC6194546,,,,Humans; Prevalence; Smoking Prevention/*methods; Public Policy; Taxes/*economics; 1; Developing Countries; Smoking; Asia Pacific; Asia/epidemiology; Commerce/statistics & numerical data; Low and middle income countries; Pacific Islands/epidemiology; Smoking-attributable mortality; Smoking/*economics/*epidemiology/mortality; Taxation; Tobacco Products/*economics; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 23ZV9KA9,journalArticle,2018,"Knai, Cecile; Petticrew, Mark; Mays, Nicholas; Capewell, Simon; Cassidy, Rebecca; Cummins, Steven; Eastmure, Elizabeth; Fafard, Patrick; Hawkins, Benjamin; Jensen, Jorgen Dejgard; Katikireddi, Srinivasa Vittal; Mwatsama, Modi; Orford, Jim; Weishaar, Heide",Systems Thinking as a Framework for Analyzing Commercial Determinants of Health.,The Milbank quarterly,,1468-0009 0887-378X,10.1111/1468-0009.12339,,"Policy Points: Worldwide, more than 70% of all deaths are attributable to noncommunicable diseases (NCDs), nearly half of which are premature and apply to individuals of working age. Although such deaths are largely preventable, effective solutions continue to elude the public health community. One reason is the considerable influence of the ""commercial determinants of health"": NCDs are the product of a system that includes powerful corporate actors, who are often involved in public health policymaking. This article shows how a complex systems perspective may be used to analyze the commercial determinants of NCDs, and it explains how this can help with (1) conceptualizing the problem of NCDs and (2) developing effective policy interventions. CONTEXT: The high burden of noncommunicable diseases (NCDs) is politically salient and eminently preventable. However, effective solutions largely continue to elude the public health community. Two pressing issues heighten this challenge: the first is the public health community's narrow approach to addressing NCDs, and the second is the involvement of corporate actors in policymaking. While NCDs are often conceptualized in terms of individual-level risk factors, we argue that they should be reframed as products of a complex system. This article explores the value of a systems approach to understanding NCDs as an emergent property of a complex system, with a focus on commercial actors. METHODS: Drawing on Donella Meadows's systems thinking framework, this article examines how a systems perspective may be used to analyze the commercial determinants of NCDs and, specifically, how unhealthy commodity industries influence public health policy. FINDINGS: Unhealthy commodity industries actively design and shape the NCD policy system, intervene at different levels of the system to gain agency over policy and politics, and legitimize their presence in public health policy decisions. CONCLUSIONS: It should be possible to apply the principles of systems thinking to other complex public health issues, not just NCDs. Such an approach should be tested and refined for other complex public health challenges.",2018-09,26/11/2018 12:49,14/04/2020 08:34,,472-498,,3,96,,Milbank Q,,,,,,,,eng,"(c) 2018 The Authors The Milbank Quarterly published by Wiley Periodicals, Inc. on behalf of The Millbank Memorial Fund.",,,,,,PMID: 30277610 PMCID: PMC6131339,,,,Humans; Health Policy; *Systems Analysis; Policy Making; Public Health Practice; 1; *Commerce/organization & administration; *noncommunicable diseases; *Social Determinants of Health/statistics & numerical data; *systems thinking; *unhealthy commodity industries; Noncommunicable Diseases/epidemiology/prevention & control; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7QI6KIZQ,journalArticle,2018,"Schwander, Bjoern; Nuijten, Mark; Hiligsmann, Mickael; Evers, Silvia M. A. A.",Event simulation and external validation applied in published health economic models for obesity: a systematic review.,Expert review of pharmacoeconomics & outcomes research,,1744-8379 1473-7167,10.1080/14737167.2018.1501680,,"INTRODUCTION: This study aims to determine methodological variations in the event simulation approaches of published health economic decision models, in the field of obesity, and to investigate whether their predictiveness and validity were investigated via external event validation techniques, which investigate how well the model reproduces reality. Areas covered: A systematic review identified a total of 87 relevant papers, of which 72 that simulated obesity-associated events were included. Most frequently simulated events were coronary heart disease ( approximately 83%), type 2 diabetes ( approximately 74%), and stroke ( approximately 66%). Only for ten published model-based health economic assessments in obesity an external event validation was performed (14%; 10 of 72), and only for one the predictiveness and validity of the event simulation was investigated in a cohort of obese subjects. Expert commentary: We identified a wide range of obesity related event simulation approaches. Published obesity models lack information on the predictive quality and validity of the applied event simulation approaches. Further work on comparing and validating these event simulation approaches is required to investigate their predictiveness and validity, which will offer guidance future modelling in the field of obesity.",2018-10,26/11/2018 12:49,14/04/2020 08:35,,529-541,,5,18,,Expert Rev Pharmacoecon Outcomes Res,,,,,,,,eng,,,,,,,PMID: 30011385,,,,"Humans; Reproducibility of Results; *Models, Economic; Computer Simulation; simulation; discrete event simulation; *Decision Making; 1; coronary heart disease; clinical events; Coronary Disease/economics/etiology; decision models; Diabetes Mellitus, Type 2/economics/etiology; external event validation; health economic assessment; Obesity; Obesity/*complications/economics; stroke; Stroke/economics/etiology; systematic review; type 2 diabetes; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QNLGHKR9,journalArticle,2017,"Tong, Rui-Peng; Yang, Xiao-Yi",[Environmental Health Risk Assessment of Contaminated Soil Based on Monte Carlo Method: A Case of PAHs].,Huan jing ke xue= Huanjing kexue,,0250-3301 0250-3301,10.13227/j.hjkx.201611040,,"In order to obtain more reasonable health risk values and get the most significant factors, probabilistic risk models based on Monte Carlo simulation were applied, the health risk level of 16 PAHs in soil was evaluated for a residential area in Shanghai, China. And, sensitivity analysis was conducted for each parameter. The results showed that, the health risks caused by PAHs followed lognormal distribution with 3.43x10(-5)+/-2.63x10(-5) for carcinogenic risk, which was between 8.10x10(-7) and 2.39x10(-4) and the probabilities exceeding 10(-6), 10(-5) and 10(-4) were 95%, 75% and less than 5%. And the value was 4.74x10(-2)+/-3.42x10(-2) for hazard quotient, which was between 1.38x10(-3) and 2.85x10(-1) and less than 1, so could be regarded negligible. As for total carcinogenic risk (TCR), the most influential PAHs were BaP, DBA and BaA, and their contribution rates were 60.41%, 26.84% and 6.56%, respectively. Among the three exposure pathways, the risk was mainly caused by oral intake with the contribution rate of 73.22%, followed by dermal contact with 26.51%. The most influential parameters were:intake amount of soil per day, exposure duration and exposed skin area with the sensitivity values of 58.35%, 50.21% and 20.51%, respectively. And body weight had a negative sensitivity with -11.66%. When it came to total hazard quotient (THQ), Pyr, FL and PA accounted for the most with 36.56%, 33.18% and 13.18%, respectively. And the oral intake and dermal contact were also primary exposure pathways with 72.21% and 26.36%. The most significant parameters were the same with TCR with the sensitivity values of 63.52%, 53.18%, 24.39% and -13.98%, respectively.",08/06/2017,26/11/2018 12:49,14/04/2020 08:35,,2522-2529,,6,38,,Huan Jing Ke Xue,,,,,,,,chi,,,,,,,PMID: 29965373,,,,Humans; *Risk Assessment; Monte Carlo Method; China; 00; Environmental Monitoring; Environmental Exposure; health risk assessment; Monte Carlo simulation; PAHs; Polycyclic Aromatic Hydrocarbons/*analysis; probabilistic risk model; soil; Soil; Soil Pollutants/*analysis; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ZI9K8H7K,journalArticle,2018,"Johnston, Sandra; Coyer, Fiona Maree; Nash, Robyn",Kirkpatrick's Evaluation of Simulation and Debriefing in Health Care Education: A Systematic Review.,The Journal of nursing education,,1938-2421 0148-4834,10.3928/01484834-20180618-03,,"BACKGROUND: Simulation is an integral component of health care education. Research suggests a positive relationship between simulation and learning outcomes. Kirkpatrick's framework is a four-level model based on the premise that learning resulting from training programs can be classified into four levels: reaction, learning, behavior, and results. Evaluation of educational impact provides valuable feedback to educators that may assist with development and improvement of teaching methods. METHOD: This review is based on the PRISMA guidelines for conducting a systematic review. Inclusion criteria included articles (a) written in the English language, (b) published between 2000 and 2016, (c) describing a debriefing intervention after high-fidelity patient simulation, and (d) based in health care. RESULTS: Thirteen studies met criteria for inclusion in the review. CONCLUSION: Results indicated a paucity of studies at the highest levels of evaluation, indicating an area where future research is needed to assist with the development and improvement of simulation education. [J Nurs Educ. 2018;57(7):393-398.].",01/07/2018,26/11/2018 12:49,14/04/2020 08:34,,393-398,,7,57,,J Nurs Educ,,,,,,,,eng,"Copyright 2018, SLACK Incorporated.",,,,,,PMID: 29958308,,,,"Humans; Randomized Controlled Trials as Topic; *Patient Simulation; High Fidelity Simulation Training/*methods; *Formative Feedback; Models, Educational; *Learning; 00; Students, Health Occupations/*psychology; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KDSGQU5P,journalArticle,2018,"Verkuyl, Margaret; Romaniuk, Daria; Mastrilli, Paula",Virtual gaming simulation of a mental health assessment: A usability study.,Nurse education in practice,,1873-5223 1471-5953,10.1016/j.nepr.2018.05.007,,"Providing safe and realistic virtual simulations could be an effective way to facilitate the transition from the classroom to clinical practice. As nursing programs begin to include virtual simulations as a learning strategy; it is critical to first assess the technology for ease of use and usefulness. A virtual gaming simulation was developed, and a usability study was conducted to assess its ease of use and usefulness for students and faculty. The Technology Acceptance Model provided the framework for the study, which included expert review and testing by nursing faculty and nursing students. This study highlighted the importance of assessing ease of use and usefulness in a virtual game simulation and provided feedback for the development of an effective virtual gaming simulation. The study participants said the virtual gaming simulation was engaging, realistic and similar to a clinical experience. Participants found the game easy to use and useful. Testing provided the development team with ideas to improve the user interface. The usability methodology provided is a replicable approach to testing virtual experiences before a research study or before implementing virtual experiences into curriculum.",2018-07,26/11/2018 12:49,14/04/2020 08:35,,83-87,,,31,,Nurse Educ Pract,,,,,,,,eng,Copyright (c) 2018 Elsevier Ltd. All rights reserved.,,,,,,PMID: 29800764,,,,"Humans; Adult; Female; Male; Middle Aged; *Virtual Reality; Adolescent; Simulation Training/*methods; Students, Nursing/psychology; Education, Nursing; 00; *Mental Health; *Nursing Assessment; Nursing education; Usability study; Virtual simulation; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HL8JSIQR,journalArticle,2018,"Tang, Wenzhong; Xia, Qing; Shan, Baoqing; Ng, Jack C.",Relationship of bioaccessibility and fractionation of cadmium in long-term spiked soils for health risk assessment based on four in vitro gastrointestinal simulation models.,The Science of the total environment,,1879-1026 0048-9697,10.1016/j.scitotenv.2018.03.154,,"The bioavailability and bioaccessibility of heavy metals mainly depend on their speciation in soils; however, the relationship between bioaccessibility and its speciation as determined as fractionation remains to be better characterized. Therefore, Cd fractionations in three types of long-term Cd-spiked soils were determined using a modified BCR method, and compared with Cd bioaccessibility data obtained from four in vitro gastrointestinal simulation assays including the IVG, PBET, SBRC, and UBM. The results shows that the majority of Cd were found in the exchangeable/acid soluble (B1) and reducible (B2) fractions (total percentage>97%) after being spiked and aged for three years, indicating high Cd bioavailability; the bioaccessibility of Cd ranged from 57.7+/-1.8% to 99.3+/-2.8% in the gastric phase, and from 5.8+/-2.0% to 35.9+/-1.8% in the intestinal phase, respectively. Among the four assays, the strongest positive correlation was observed between Cd bioaccessibility based on the PBET assay and its B1 fraction in the spiked soils (r(2) gastric: 0.62 and intestinal: 0.52), suggesting that the PBET assay maybe more suitable for determining Cd bioaccessibility in aged contaminated soils.",01/08/2018,26/11/2018 12:49,14/04/2020 08:35,,1582-1589,,,631-632,,Sci Total Environ,,,,,,,,eng,Copyright (c) 2018 Elsevier B.V. All rights reserved.,,,,,,PMID: 29727982,,,,"Humans; Models, Biological; 00; Bioaccessibility; Bioavailability; Cadmium/*metabolism; Chemical Fractionation; Gastrointestinal Tract; Heavy metal; Intestines/*metabolism; Soil contamination; Soil Pollutants/*metabolism; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3ZLSHLV2,journalArticle,2018,"Ogard-Repal, Anita; De Presno, Asne Knutson; Fossum, Mariann",Simulation with standardized patients to prepare undergraduate nursing students for mental health clinical practice: An integrative literature review.,Nurse education today,,1532-2793 0260-6917,10.1016/j.nedt.2018.04.018,,"OBJECTIVE: To evaluate the available evidence supporting the efficacy of using simulation with standardized patients to prepare nursing students for mental health clinical practice. DESIGN: Integrative literature review. DATA SOURCES: A systematic search of the electronic databases CINAHL (EBSCOhost), Embase, MEDLINE, PsycINFO, and SveMed+ was conducted to identify empirical studies published until November 2016. Multiple search terms were used. Original empirical studies published in English and exploring undergraduate nursing students' experiences of simulation with standardized patients as preparation for mental health nursing practice were included. A search of reference lists and gray literature was also conducted. In total, 1677 studies were retrieved; the full texts of 78 were screened by 2 of the authors, and 6 studies reminded in the review. REVIEW METHODS: The authors independently reviewed the studies in three stages by screening the titles, abstracts, and full texts, and the quality of the included studies was assessed in the final stage. Design-specific checklists were used for quality appraisal. The thematic synthesizing method was used to summarize the findings of the included studies. RESULTS: The studies used four different research designs, both qualitative and quantitative. All studies scored fairly low in the quality appraisal. The five themes identified were enhanced confidence, clinical skills, anxiety regarding the unknown, demystification, and self-awareness. CONCLUSIONS: The findings of this study indicate that simulation with standardized patients could decrease students' anxiety level, shatter pre-assumptions, and increase self-confidence and self-awareness before entering clinical practice in mental health. More high-quality studies with larger sample sizes are required because of the limited evidence provided by the six studies in the present review.",2018-07,26/11/2018 12:49,14/04/2020 08:35,,149-157,,,66,,Nurse Educ Today,,,,,,,,eng,Copyright (c) 2018 Elsevier Ltd. All rights reserved.,,,,,,PMID: 29704702,,,,"Humans; *Patient Simulation; Qualitative Research; *Students, Nursing; Nursing students; Education; 00; Clinical Competence/*standards; *Psychiatric Nursing; Clinical practice; Psychiatric nursing; Simulation training; Standardized patients; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ZESSPS4I,journalArticle,2018,"Haerling, Katie A.",Cost-Utility Analysis of Virtual and Mannequin-Based Simulation.,Simulation in healthcare : journal of the Society for Simulation in Healthcare,,1559-713X 1559-2332,10.1097/SIH.0000000000000280,,"INTRODUCTION: The purposes of this study were to (1) compare learning outcomes between students who participated in mannequin-based simulation activities and students who participated in virtual simulation activities and (2) describe a cost-utility analysis comparing the two types of simulation activities in terms of costs and multiple measures of effectiveness. METHODS: Nursing student participants were randomly assigned to one of two experimental groups to complete either a mannequin-based or virtual simulation activity. The simulation scenario was the same for both groups and involved the care of a hospitalized patient experiencing a chronic obstructive pulmonary disease exacerbation. Participants completed presimulation and postsimulation assessments reflecting qualitative and quantitative measures of learning. A random sample of participants from each group completed a postsimulation performance assessment during which they interacted one on one with a standardized patient. RESULTS: Eighty-four nursing students were enrolled in the study and completed the simulation activities. There were no significant differences in quantitative measures of learning or performance between participants in the mannequin-based and virtual simulation groups. Participants' qualitative responses to postintervention written reflections and questions yielded additional data for describing learning from the two interventions. In the cost-utility analysis, the virtual simulation activity had a more favorable cost-utility ratio of US $1.08 versus the mannequin-based simulation activity's US $3.62. CONCLUSIONS: Healthcare educators striving to make evidence-based decisions about how to best employ simulation pedagogy may consider these findings about the cost utility of various simulation modalities. However, additional research is needed.",2018-02,26/11/2018 12:49,14/04/2020 08:34,,33-40,,1,13,,Simul Healthc,,,,,,,,eng,,,,,,,PMID: 29373382,,,,Humans; Cost-Benefit Analysis; Clinical Competence; Simulation Training/*economics; *User-Computer Interface; *Manikins; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MACHBMQ7,journalArticle,2018,"Devers, Veffa",Use of Simulation-Based Training to Aid in Implementing Complex Health Technology.,Biomedical instrumentation & technology,,0899-8205 0899-8205,10.2345/0899-8205-52.1.44,,"Clinicians are adult learners in a complex environment that historically does not invest in training in a way that is conducive to these types of learners. Adult learners are independent, self-directed, and goal oriented. In today's fast-paced clinical setting, a practical need exists for nurses and clinicians to master the technology they use on a daily basis, especially as medical devices have become more interconnected and complex. As hospitals look to embrace new technologies, medical device companies must provide clinical end-user training. This should be a required part of the selection process when considering the purchase of any complex medical technology. However, training busy clinicians in a traditional classroom setting can be difficult and costly. A simple, less expensive solution is online simulation training. This interactive training provides a virtual, ""hands-on"" end-user experience in advance of implementing new equipment. Online simulation training ensures knowledge retention and comprehension and, most importantly, that the training leads to end-user satisfaction and the ability to confidently operate new equipment. A review of the literature revealed that online simulation, coupled with the use of adult learning principles and experiential learning, may enhance the experience of clinical end users.",2018-01,26/11/2018 12:49,14/04/2020 08:34,,44-48,,1,52,,Biomed Instrum Technol,,,,,,,,eng,,,,,,,PMID: 29350974,,,,Humans; Adult; Clinical Competence; Learning; User-Computer Interface; 00; Patient-Centered Care/*organization & administration; *Computer-Assisted Instruction/methods; *Health Plan Implementation/methods/organization & administration/standards; Biomedical Technology/*education/methods/organization & administration; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3ZTHEWFW,journalArticle,2018,"Dalwood, Narelle; Maloney, Stephen; Cox, Narelle; Morgan, Prue",Preparing Physiotherapy Students for Clinical Placement: Student Perceptions of Low-Cost Peer Simulation. A Mixed-Methods Study.,Simulation in healthcare : journal of the Society for Simulation in Healthcare,,1559-713X 1559-2332,10.1097/SIH.0000000000000276,,"INTRODUCTION: Simulation is increasingly used in health care education, yet the organizational and financial costs can be prohibitive. This study aimed to investigate whether peer simulation is perceived by third-year undergraduate physiotherapy students as valuable for clinical placement preparation. METHODS: Third-year undergraduate physiotherapy students participated in a 9-week peer simulation program, using each other as patients, and were invited to complete two surveys evaluating perceptions of the program. The program consisted of weekly patient interactions during which students were required to assess and treat a ""patient"" under strict simulation guidelines and in accordance with stated learning objectives. Items rated included self-perceived skills, confidence, time management, and clinical placement readiness and included collection of qualitative responses. Surveys were released at commencement and completion of the simulation program. RESULTS: Of 79 third-year students, 63% completed survey 1 and 66% completed survey 2. Students had high expectations of the program and these were consistently met. Peer simulation rated highly for all items, including identifying knowledge and skill deficits, and improving confidence, clinical reasoning, time management, and communication. Simulation was considered safe, supportive, engaging, and valuable for clinical placement preparation. Students identified some lack of authenticity when working with peers. CONCLUSIONS: Peer simulation was perceived by students as valuable in preparing them for clinical placement, despite a perceived lack of realism. These findings support the use of peer simulation as an alternative to the use of more formalized standardized patients in an undergraduate physiotherapy program. Further investigation is required to establish a detailed cost analysis of the program and to determine the amount of realism required to optimize the benefits of this promising educational strategy.",2018-06,26/11/2018 12:49,14/04/2020 08:34,,181-187,,3,13,,Simul Healthc,,,,,,,,eng,,,,,,,PMID: 29346226,,,,Humans; Adult; Clinical Competence; Female; Male; Young Adult; *Patient Simulation; Communication; *Peer Group; Attitude of Health Personnel; 00; Clinical Clerkship/*methods; Physical Therapy Modalities/*education; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, U5NEGXIP,journalArticle,2018,"Kajiwara, Naohiro; Kato, Yasufumi; Hagiwara, Masaru; Kakihana, Masatoshi; Ohira, Tatsuo; Kawate, Norihiko; Ikeda, Norihiko",Cost-Benefit Performance Simulation of Robot-Assisted Thoracic Surgery As Required for Financial Viability under the 2016 Revised Reimbursement Paradigm of the Japanese National Health Insurance System.,Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia,,2186-1005 1341-1098,10.5761/atcs.oa.17-00094,,"PURPOSE: To discuss the cost-benefit performance (CBP) and establish a medical fee system for robotic-assisted thoracic surgery (RATS) under the Japanese National Health Insurance System (JNHIS), which is a system not yet firmly established. METHODS: All management steps for RATS are identical, such as preoperative and postoperative management. This study examines the CBP based on medical fees of RATS under the JNHIS introduced in 2016. RESULTS: Robotic-assisted laparoscopic prostatectomy (RALP) and robotic-assisted partial nephrectomy (RAPN) now receive insurance reimbursement under the category of use of support devices for endoscopic surgery ($5420 and $3485, respectively). If the same standard amount were to be applied to RATS, institutions would need to perform at least 150 or 300 procedures thoracic operation per year to show a positive CBP ($317 per procedure as same of RALP and $130 per procedure as same of RAPN, respectively). CONCLUSION: Robotic surgery in some areas receives insurance reimbursement for its ""supportive"" use for endoscopic surgery as for RALP and RAPN. However, at present, it is necessary to perform da Vinci Surgical System Si (dVSi) surgery at least 150-300 times in a year in a given institution to prevent a deficit in income.",20/04/2018,26/11/2018 12:49,14/04/2020 08:34,,73-80,,2,24,,Ann Thorac Cardiovasc Surg,,,,,,,,eng,,,,,,,PMID: 29343662 PMCID: PMC5930259,,,,"Humans; Cost-Benefit Analysis; *Health Care Costs; Computer Simulation; Models, Economic; Japan; 00; cost-benefit performance; da Vinci Surgical System; Insurance, Health, Reimbursement/*economics; Japanese National Health Insurance System; National Health Programs/*economics; Process Assessment (Health Care)/*economics; robot-assisted thoracic surgery; Robotic Surgical Procedures/*economics/methods; Thoracic Surgical Procedures/*economics/methods; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, K3UMY9IF,journalArticle,2018,"de Melo, Brena Carvalho Pinto; Rodrigues Falbo, Ana; Sorensen, Jette Led; van Merrienboer, Jeroen J. G.; van der Vleuten, Cees",Self-perceived long-term transfer of learning after postpartum hemorrhage simulation training.,International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics,,1879-3479 0020-7292,10.1002/ijgo.12442,,"OBJECTIVE: To explore long-term transfer (application of acquired knowledge and skills on the job) after postpartum hemorrhage simulation training based on either instructional design (ID) principles or conventional best practice. METHODS: In this qualitative study, semi-structured interviews with obstetrics and gynecology healthcare practitioners were conducted between August 7 and September 26, 2015, in Recife, Brazil. The participants were randomly selected from each of two postpartum hemorrhage simulations attended 2 years earlier (one ID and one conventional best practice). Thematic analysis was used to explore (1) residents' perceptions of long-term transfer of learning, (2) ID elements influencing the perceived long-term transfer, and (3) differences in the participants' perceptions according to the type of simulation attended. RESULTS: There were 12 interview participants. After either simulation format, residents perceived long-term transfer effects. Training design factors influencing transfer were, in their opinion, related to trainees' characteristics, simulation design, and workplace environment. Trainees who participated in the ID-based simulation perceived better communication skills and better overall situational awareness: ""I didn't do that before."" CONCLUSION: All residents perceived long-term transfer after simulation training for postpartum hemorrhage. Those who attended the ID format additionally perceived improvements in communication skills and situational awareness, which are fundamental factors in the management of postpartum hemorrhage.",2018-05,26/11/2018 12:49,14/04/2020 08:34,,261-267,,2,141,,Int J Gynaecol Obstet,,,,,,,,eng,(c) 2018 International Federation of Gynecology and Obstetrics.,,,,,,PMID: 29330842,,,,Humans; *Simulation Training; Adult; Clinical Competence; Female; Learning; Male; Qualitative Research; Communication; Pregnancy; Postpartum Hemorrhage/*therapy; Awareness; Brazil; Perception; Self Concept; 00; Simulation training; *Internship and Residency; *Transfer (Psychology); Gynecology/education; Instruction; Obstetrics/education; Postpartum hemorrhage; Situational awareness; Training transfer; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GJLRU4D5,journalArticle,2018,"Feldacker, Caryl; Makunike-Chikwinya, Batsirai; Holec, Marrianne; Bochner, Aaron F.; Stepaniak, Abby; Nyanga, Robert; Xaba, Sinokuthemba; Kilmarx, Peter H.; Herman-Roloff, Amy; Tafuma, Taurayi; Tshimanga, Mufuta; Sidile-Chitimbire, Vuyelwa T.; Barnhart, Scott","Implementing voluntary medical male circumcision using an innovative, integrated, health systems approach: experiences from 21 districts in Zimbabwe.",Global health action,,1654-9880 1654-9880,10.1080/16549716.2017.1414997,,"BACKGROUND: Despite increased support for voluntary medical male circumcision (VMMC) to reduce HIV incidence, current VMMC progress falls short. Slow progress in VMMC expansion may be partially attributed to emphasis on vertical (stand-alone) over more integrated implementation models that are more responsive to local needs. In 2013, the ZAZIC consortium began implementation of a 5-year, integrated VMMC program jointly with Ministry of Health and Child Care (MoHCC) in Zimbabwe. OBJECTIVE: To explore ZAZIC's approach emphasizing existing healthcare workers and infrastructure, increasing program sustainability and resilience. METHODS: A process evaluation utilizing routine quantitative data. Interviews with key MoHCC informants illuminate program strengths and weaknesses. METHODS: A process evaluation utilizing routine quantitative data. Interviews with key MoHCC informants illuminate program strengths and weaknesses. RESULTS: In start-up and year 1 (March 2013-September, 2014), ZAZIC expanded from two to 36 static VMMC sites and conducted 46,011 VMMCs; 39,840 completed from October 2013 to September 2014. From October 2014 to September 2015, 44,868 VMMCs demonstrated 13% increased productivity. In October, 2015, ZAZIC was required by its donor to consolidate service provision from 21 to 10 districts over a 3-month period. Despite this shock, 57,282 VMMCs were completed from October 2015 to September 2016 followed by 44,414 VMMCs in only 6 months, from October 2016 to March 2017. Overall, ZAZIC performed 192,575 VMMCs from March 2013 to March, 2017. The vast majority of VMMCs were completed safely by MoHCC staff with a reported moderate and severe adverse event rate of 0.3%. CONCLUSION: The safety, flexibility, and pace of scale-up associated with the integrated VMMC model appears similar to vertical delivery with potential benefits of capacity building, sustainability and health system strengthening. These models also appear more adaptable to local contexts. Although more complicated than traditional approaches to program implementation, attention should be given to this country-led approach for its potential to spur positive health system changes, including building local ownership, capacity, and infrastructure for future public health programming.",2018,26/11/2018 12:49,14/04/2020 08:34,,1414997,,1,11,,Glob Health Action,,,,,,,,eng,,,,,,,PMID: 29322867 PMCID: PMC5769777,,,,"Humans; Program Evaluation; Adult; Male; Child; Systems Analysis; Incidence; Public Health; Zimbabwe; 00; *health system strengthening; *innovations in healthcare delivery; *integrated service models; *Voluntary medical male circumcision; *Zimbabwe; Capacity Building/organization & administration; Child Health; Circumcision, Male/*ethnology; Government Programs/*organization & administration; Health Personnel/education/organization & administration; HIV Infections/prevention & control; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TBUSZZ8M,journalArticle,2017,"Sharafi, Zahra; Mousavi, Amin; Ayatollahi, Seyyed Mohammad Taghi; Jafari, Peyman",Assessment of Differential Item Functioning in Health-Related Outcomes: A Simulation and Empirical Analysis with Hierarchical Polytomous Data.,Computational and mathematical methods in medicine,,1748-6718 1748-670X,10.1155/2017/7571901,,"Background: The purpose of this study was to evaluate the effectiveness of two methods of detecting differential item functioning (DIF) in the presence of multilevel data and polytomously scored items. The assessment of DIF with multilevel data (e.g., patients nested within hospitals, hospitals nested within districts) from large-scale assessment programs has received considerable attention but very few studies evaluated the effect of hierarchical structure of data on DIF detection for polytomously scored items. Methods: The ordinal logistic regression (OLR) and hierarchical ordinal logistic regression (HOLR) were utilized to assess DIF in simulated and real multilevel polytomous data. Six factors (DIF magnitude, grouping variable, intraclass correlation coefficient, number of clusters, number of participants per cluster, and item discrimination parameter) with a fully crossed design were considered in the simulation study. Furthermore, data of Pediatric Quality of Life Inventory (PedsQL) 4.0 collected from 576 healthy school children were analyzed. Results: Overall, results indicate that both methods performed equivalently in terms of controlling Type I error and detection power rates. Conclusions: The current study showed negligible difference between OLR and HOLR in detecting DIF with polytomously scored items in a hierarchical structure. Implications and considerations while analyzing real data were also discussed.",2017,26/11/2018 12:49,14/04/2020 08:35,,7571901,,,2017,,Comput Math Methods Med,,,,,,,,eng,,,,,,,PMID: 29312463 PMCID: PMC5613630,,,,"Humans; Female; Male; Child; *Computer Simulation; Adolescent; Algorithms; Models, Statistical; *Quality of Life; Health Status; 00; Computational Biology/*methods; Psychometrics/*methods; Students/psychology/statistics & numerical data; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9JWABYH7,journalArticle,2017,"Takahashi, Hideto; Takahashi, Kunihiko; Shimura, Hiroki; Yasumura, Seiji; Suzuki, Satoru; Ohtsuru, Akira; Midorikawa, Sanae; Ohira, Tetsuya; Ohto, Hitoshi; Yamashita, Shunichi; Kamiya, Kenji",Simulation of expected childhood and adolescent thyroid cancer cases in Japan using a cancer-progression model based on the National Cancer Registry: Application to the first-round thyroid examination of the Fukushima Health Management Survey.,Medicine,,1536-5964 0025-7974,10.1097/MD.0000000000008631,,"During the 4 years following the nuclear power plant accident of 2011, 39 males and 77 females were diagnosed with or suspected of having cancer based on the first-round thyroid examination of the Fukushima Health Management Survey (FHMS) targeting residents aged <19 years in Fukushima. Prior comparisons between the observed data and Japan's National Cancer Registry (NCR) data suggested that this incidence might be excessive, but such comparisons are problematic because they need not only to adjust index unit (prevalence proportion vs incidence rate), but also examine characteristics (complete enumeration mass screening for the aged 0 to 18 years vs detections in clinical settings for all the residents) and sensitivity of the examinations. The purpose of this study is to build a common model applicable to any region in Japan under nonaccident conditions, and estimate the expected prevalence based on the numbers of subjects surveyed in the FHMS using a simulation of the sensitivity.The cancer-progression model is an extension of Day and Walter's, the parameters of which were estimated by minimizing the weighted root mean squared error between the average age-specific thyroid incident rates from 2001 to 2010 in the NCR and those determined by the model. We estimated expected detectable prevalent cases by the model with their examination-participation proportions and simulated several sensitivities.Median sojourn times were 34 years (males) and 30 years (females) by the model. Simulation results showed that the numbers of observed prevalent cases were within the 95% confidence intervals of the expected prevalent cases with several sensitivities in each gender.We successfully built a cancer-progression model of thyroid cancer based on Japan's NCR data under no accident conditions. It is a tool for comparing the observed prevalence data of examinations and the NCR data, which resolved 3 issues of index unit, the characteristics and sensitivity of the examinations. Simulation results imply that the number of observed thyroid cancer cases can be detected by the FHMS first-round thyroid screening at several sensitivities under no accident conditions.",2017-12,26/11/2018 12:49,14/04/2020 08:35,,e8631,,48,96,,Medicine (Baltimore),,,,,,,,eng,,,,,,,PMID: 29310337 PMCID: PMC5728738,,,,"Humans; Forecasting; Female; Male; Young Adult; Child; Adolescent; Computer Simulation; Incidence; Child, Preschool; Infant; Prevalence; Infant, Newborn; Registries; Health Surveys; 00; *Fukushima Nuclear Accident; Neoplasms, Radiation-Induced/*epidemiology/*etiology; Thyroid Neoplasms/*epidemiology/*etiology; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3ZUBWJNR,journalArticle,2017,"Arenas, Daniel J.; Lett, Lanair A.; Klusaritz, Heather; Teitelman, Anne M.",A Monte Carlo simulation approach for estimating the health and economic impact of interventions provided at a student-run clinic.,PloS one,,1932-6203 1932-6203,10.1371/journal.pone.0189718,,"BACKGROUND: Student Run Clinics (SRCs) are a common aspect of medical education, present at more than half of US medical schools, and noted for providing care to communities that might otherwise lack access, including the uninsured and underinsured. To date, few studies have rigorously quantified the health and economic benefits of SRCs, and the present study remedies that. METHODS AND FINDINGS: We used Monte Carlo simulations to estimate the health impact of common preventive health interventions applied to individuals in quality-adjusted life-years (QALYs). We then used those measurements to estimate the health and economic impact of United Community Clinic (UCC), a student-run clinic in Philadelphia, PA. We found that with an annual operating budget of $50,000, UCC saves 6.5 QALYs, corresponding to over $850,000 saved. CONCLUSIONS: Using Monte Carlo simulation methods, the health and economic impact of SRCs can be reasonably estimated to demonstrate the utility of SRCs and justify their growing importance in the healthcare delivery landscape of the US.",2017,26/11/2018 12:49,14/04/2020 08:34,,e0189718,,12,12,,PLoS One,,,,,,,,eng,,,,,,,PMID: 29284026 PMCID: PMC5746244,,,,"Humans; Quality-Adjusted Life Years; *Monte Carlo Method; 1; *Students, Medical; Ambulatory Care Facilities/economics/*organization & administration; Education, Medical/*organization & administration; Philadelphia; Preventive Health Services/economics/organization & administration; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, AXUPRBTP,journalArticle,2018,"Plack, Margaret M.; Goldman, Ellen F.; Scott, Andrea R.; Pintz, Christine; Herrmann, Debra; Kline, Kathleen; Thompson, Tracey; Brundage, Shelley B.","Systems Thinking and Systems-Based Practice Across the Health Professions: An Inquiry Into Definitions, Teaching Practices, and Assessment.",Teaching and learning in medicine,,1532-8015 1040-1334,10.1080/10401334.2017.1398654,,"Phenomenon: Systems thinking is the cornerstone of systems-based practice (SBP) and a core competency in medicine and health sciences. Literature regarding how to teach or apply systems thinking in practice is limited. This study aimed to understand how educators in medicine, physical therapy, physician assistant, nursing, and speech-language pathology education programs teach and assess systems thinking and SBP. APPROACH: Twenty-six educators from seven different degree programs across the five professions were interviewed and program descriptions and relevant course syllabi were reviewed. Qualitative analysis was iterative and incorporated inductive and deductive methods as well as a constant comparison of units of data to identify patterns and themes. FINDINGS: Six themes were identified: 1) participants described systems thinking as ranging across four major levels of healthcare (i.e., patient, care team, organization, and external environment); 2) participants associated systems thinking with a wide range of activities across the curriculum including quality improvement, Inter-professional education (IPE), error mitigation, and advocacy; 3) the need for healthcare professionals to understand systems thinking was primarily externally driven; 4) participants perceived that learning systems thinking occurred mainly informally and experientially rather than through formal didactic instruction; 5) participants characterized systems thinking content as interspersed across the curriculum and described a variety of strategies for teaching and assessing it; 6) participants indicated a structured framework and inter-professional approach may enhance teaching and assessment of systems thinking. Insights: Systems thinking means different things to different health professionals. Teaching and assessing systems thinking across the health professions will require further training and practice. Tools, techniques, taxonomies and expertise outside of healthcare may be used to enhance the teaching, assessment, and application of systems thinking and SBP to clinical practice; however, these would need to be adapted and refined for use in healthcare.",2018-09,26/11/2018 12:49,14/04/2020 08:35,,242-254,,3,30,,Teach Learn Med,,,,,,,,eng,,,,,,,PMID: 29283669,,,,Humans; Clinical Competence; Female; Male; Curriculum; Qualitative Research; *Systems Analysis; systems thinking; Health Personnel/*education; Interviews as Topic; 00; *Teaching; assessment; medicine and health sciences education; systems-based practice; teaching; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FPJJMNN8,journalArticle,2017,"Clarke, Karen-Ann; Andersen, Patrea; Loth, Jo",IMMERSIVE MENTAL HEALTH SIMULATION HELPS STUDENTS WITH CHALLENGING CONVERSATIONS.,Australian nursing & midwifery journal,,2202-7114 2202-7114,,,"Simulation within nursing education is becoming a popular means of facilitating competency, where there is a tendency for this to focus on the acquisition and development of clinical and technical skills.",2017-04,26/11/2018 12:49,14/04/2020 08:34,,36,,9,24,,Aust Nurs Midwifery J,,,,,,,,eng,,,,,,,PMID: 29272089,,,,"Humans; Clinical Competence; *Patient Simulation; Australia; *Students, Nursing; 00; *Education, Nursing; Mental Health/*education; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ZL9NQVNI,journalArticle,2017,"Brunette, Maria J.; Curioso, Walter H.",[Integrated mobile health systems: Role of socio-cultural factors and the socio-technical systems approach].,Revista peruana de medicina experimental y salud publica,,1726-4642 1726-4634,10.17843/rpmesp.2017.343.2859,,"This paper discusses the role of socio-cultural factors in strengthening integrated mobile health systems. Emphasis is placed on the importance that any initiative in mobile health should consider the analysis of socio-cultural factors during the process of the development and implementation of programs and research interventions. The socio-cultural and socio-technical approach also consider the human factor and considers the conditions of the environment and the context beyond the technological resources of the mobile health system and the infrastructure that supports it. Methodologies such as observational studies, focus groups, and in-depth interviews should be included ideally in any mobile health study. We also present a case study in the north area of Lima (Peru), adapting the Community-Based Participatory Research platform that is based on a socio-technical approach and evaluates the socio-cultural approach with the objective to optimize the diagnosis process of tuberculosis using mobile health.",2017-09,26/11/2018 12:49,14/04/2020 08:34,,544-550,,3,34,,Rev Peru Med Exp Salud Publica,,,,,,,,spa,,,,,,,PMID: 29267781,,,,"Humans; *Systems Analysis; *Telemedicine; *Delivery of Health Care, Integrated; Information Technology; 00; Cultural Characteristics; Peru; Sociological Factors; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BIC4QCER,journalArticle,2017,"Zapata-Vazquez, Rita Esther; Alvarez-Cervera, Fernando Jose; Alonzo-Vazquez, Felipe Manuel; Garcia-Lira, Jose Ramon; Granados-Garcia, Victor; Perez-Herrera, Norma Elena; Medina-Moreno, Manuel",Cost Effectiveness of Intracranial Pressure Monitoring in Pediatric Patients with Severe Traumatic Brain Injury: A Simulation Modeling Approach.,Value in health regional issues,,2212-1102 2212-1099,10.1016/j.vhri.2017.08.011,,"OBJECTIVES: To conduct an economic evaluation of intracranial pressure (ICP) monitoring on the basis of current evidence from pediatric patients with severe traumatic brain injury, through a statistical model. METHODS: The statistical model is a decision tree, whose branches take into account the severity of the lesion, the hospitalization costs, and the quality-adjusted life-year for the first 6 months post-trauma. The inputs consist of probability distributions calculated from a sample of 33 surviving children with severe traumatic brain injury, divided into two groups: with ICP monitoring (monitoring group) and without ICP monitoring (control group). The uncertainty of the parameters from the sample was quantified through a probabilistic sensitivity analysis using the Monte-Carlo simulation method. The model overcomes the drawbacks of small sample sizes, unequal groups, and the ethical difficulty in randomly assigning patients to a control group (without monitoring). RESULTS: The incremental cost in the monitoring group was Mex$3,934 (Mexican pesos), with an increase in quality-adjusted life-year of 0.05. The incremental cost-effectiveness ratio was Mex$81,062. The cost-effectiveness acceptability curve had a maximum at 54% of the cost effective iterations. The incremental net health benefit for a willingness to pay equal to 1 time the per capita gross domestic product for Mexico was 0.03, and the incremental net monetary benefit was Mex$5,358. CONCLUSIONS: The results of the model suggest that ICP monitoring is cost effective because there was a monetary gain in terms of the incremental net monetary benefit.",2017-12,26/11/2018 12:49,14/04/2020 08:35,,96-102,,,14,,Value Health Reg Issues,,,,,,,,eng,Copyright (c) 2017. Published by Elsevier Inc.,,,,,,PMID: 29254549,,,,"Humans; Quality-Adjusted Life Years; Female; Male; *Cost-Benefit Analysis; *Brain Injuries, Traumatic/therapy; *Models, Statistical; *Monitoring, Physiologic/methods/standards; brain injuries; Child; cost-benefit analysis; decision support techniques; Decision Support Techniques; Health Care Costs/statistics & numerical data; Intracranial Pressure/*physiology; Mexico; Pediatrics; physiologic monitoring; probabilistic models; uncertainty; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LRZMN2FA,journalArticle,2017,"Samuels, Fiona; Jones, Nicola; Abu Hamad, Bassam",Psychosocial support for adolescent girls in post-conflict settings: beyond a health systems approach.,Health policy and planning,,1460-2237 0268-1080,10.1093/heapol/czx127,,"Adaptive and adequately resourced health systems are necessary to achieve good health outcomes in post-conflict settings, however domains beyond the health system are also critical to ensure broader wellbeing. This paper focuses on the importance of psychosocial support services for adolescent girls in fragile contexts. Its starting point is that adolescence is a pivotal time in the life course but given the physical, cognitive and emotional changes triggered by the onset of puberty, it can also be a period of heightened sensitivity and vulnerability to trauma, social isolation, bullying by peers, a lack of supportive adults and gender-based and sexual violence. Our findings highlight why humanitarian and biomedical approaches in their current form are inadequate to address these complexities. Drawing on qualitative fieldwork (consisting of in-depth and key informant interviews as well as group discussions in Gaza, Liberia and Sri Lanka involving a total of 386 respondents across the three countries), we argue that going beyond biomedical approaches and considering the social determinants of health, including approaches to tackle discriminatory gendered norms and barriers to service access, are critical for achieving broader health and wellbeing. While all three case study countries are classified as post-conflict, the political economy dynamics vary with associated implications for experiences of psychosocial vulnerabilities and the service environment. The study concludes by reflecting on actions to address psychosocial vulnerabilities facing adolescent girls. These include: tailoring services to ensure gender and age-sensitivity; investing in capacity building of service providers to promote service uptake; and enhancing strategies to regulate and coordinate actors providing mental health and psychosocial support services.",01/12/2017,26/11/2018 12:49,14/04/2020 08:35,,v40-v51,,suppl_5,32,,Health Policy Plan,,,,,,,,eng,(c) The Author 2017. Published by Oxford University Press in association with The London School of Hygiene and Tropical Medicine.,,,,,,PMID: 29244106 PMCID: PMC5886144,,,,Humans; Socioeconomic Factors; Female; Adolescent; health; wellbeing; Psychosocial; 00; *Adolescent Health; *Psychosocial Support Systems; *Women's Health; adolescence; Armed Conflicts/psychology; Gaza; girls; Liberia; Mental Health Services; Middle East; post-conflict; Sex Offenses/psychology; Sexism; social determinants of health; Social Norms; Sri Lanka; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, SPJIE8QS,journalArticle,2017,"Choi, Karmel W.; Batchelder, Abigail W.; Ehlinger, Peter P.; Safren, Steven A.; O'Cleirigh, Conall","Applying network analysis to psychological comorbidity and health behavior: Depression, PTSD, and sexual risk in sexual minority men with trauma histories.",Journal of consulting and clinical psychology,,1939-2117 0022-006X,10.1037/ccp0000241,,"OBJECTIVE: High rates of depression and posttraumatic stress disorder (PTSD) contribute to sexual risk, particularly in men who have sex with men (MSM) who have experienced childhood sexual abuse. The comorbidity between depression and PTSD and mechanisms by which they contribute to sexual risk in MSM remain unclear. This study sought to demonstrate the feasibility and utility of a network approach to (a) characterize symptom interconnections between depression and PTSD in MSM, (b) identify specific symptoms related to sexual risk behavior, and (c) compare symptom networks across groups at different levels of risk. METHOD: Cross-sectional baseline data were collected from 296 HIV-negative urban MSM as part of a multisite randomized intervention trial. Symptoms of depression and PTSD were self-reported along with sexual risk behavior. Analyses were performed in R using regularized partial correlation network modeling. RESULTS: Network analyses revealed complex associations between depression and PTSD symptoms and in relation to sexual risk behavior. While symptoms clustered within their respective disorders, depression and PTSD were connected at key symptom nodes (e.g., sleep, concentration). Specific symptoms (e.g., avoiding thoughts and feelings) were linked to sexual risk behavior. Network comparisons across risk groups suggested avoidant processes could be more readily activated in higher-risk individuals, whereas hyperarousal symptoms may be more salient and protective for lower-risk individuals. CONCLUSIONS: This study is one of the earliest network analyses of depression and PTSD, and first to extend this inquiry to health behavior. Symptom-level investigations may clarify mechanisms underlying psychological comorbidity and behavioral risk in MSM and refine targets for intervention/prevention. (PsycINFO Database Record",2017-12,26/11/2018 12:49,14/04/2020 08:34,,1158-1170,,12,85,,J Consult Clin Psychol,,,,,,,,eng,"(c) 2017 APA, all rights reserved).",,,,,,PMID: 29189032 PMCID: PMC5724394,,,,"Humans; Adult; Male; Middle Aged; Cross-Sectional Studies; *Health Behavior; *Risk-Taking; 00; Adult Survivors of Child Abuse/*psychology; Depression/complications/*psychology; Depressive Disorder/complications/*psychology; Sexual and Gender Minorities/*psychology; Sexual Behavior/*psychology; Stress Disorders, Post-Traumatic/complications/*psychology; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XM2BJWVJ,journalArticle,2017,"Weeks, Margaret R.; Li, Jianghong; Lounsbury, David; Green, Helena Danielle; Abbott, Maryann; Berman, Marcie; Rohena, Lucy; Gonzalez, Rosely; Lang, Shawn; Mosher, Heather",Using Participatory System Dynamics Modeling to Examine the Local HIV Test and Treatment Care Continuum in Order to Reduce Community Viral Load.,American journal of community psychology,,1573-2770 0091-0562,10.1002/ajcp.12204,,"Achieving community-level goals to eliminate the HIV epidemic requires coordinated efforts through community consortia with a common purpose to examine and critique their own HIV testing and treatment (T&T) care system and build effective tools to guide their efforts to improve it. Participatory system dynamics (SD) modeling offers conceptual, methodological, and analytical tools to engage diverse stakeholders in systems conceptualization and visual mapping of dynamics that undermine community-level health outcomes and identify those that can be leveraged for systems improvement. We recruited and engaged a 25-member multi-stakeholder Task Force, whose members provide or utilize HIV-related services, to participate in SD modeling to examine and address problems of their local HIV T&T service system. Findings from the iterative model building sessions indicated Task Force members' increasingly complex understanding of the local HIV care system and demonstrated their improved capacity to visualize and critique multiple models of the HIV T&T service system and identify areas of potential leverage. Findings also showed members' enhanced communication and consensus in seeking deeper systems understanding and options for solutions. We discuss implications of using these visual SD models for subsequent simulation modeling of the T&T system and for other community applications to improve system effectiveness.",2017-12,26/11/2018 12:49,14/04/2020 08:34,,584-598,,03-Apr,60,,Am J Community Psychol,,,,,,,,eng,(c) Society for Community Research and Action 2017.,,,,,,PMID: 29154393 PMCID: PMC5729085,,,,Delivery of Health Care/*organization & administration; Humans; Community-Based Participatory Research; *Continuity of Patient Care; Systems Analysis; 1; *Viral Load; *Health Services; Advisory Committees; Community viral load; Group model building; HIV Infections/*diagnosis/drug therapy; Human immunodeficiency virus; Participatory; System dynamics modeling; Test and treatment; 420,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, AC9G2LDT,journalArticle,2017,"Tesniere, Antoine; Fleury, Cynthia",[Simulation in health to improve the delivery of care].,Soins; la revue de reference infirmiere,,0038-0814 0038-0814,10.1016/j.soin.2017.09.014,,"Simulation in health care is a very effective training tool. Using mannequins, 'standardised patients' or virtual care environments, it encourages participants to reflect on nursing practices while practising in a safe and controlled space.",2017-11,26/11/2018 12:49,14/04/2020 08:35,,56-59,,820,62,,Soins,,,,,,,,fre,Copyright (c) 2017 Elsevier Masson SAS. All rights reserved.,,,,,,PMID: 29153222,,,,Humans; Delivery of Health Care/*standards; *Simulation Training; *Quality Improvement; simulation; safety; *Manikins; care; 00; environnement virtuel; haute fidelite; high fidelity; patient standardise; qualite; quality; securite; soin; standardised patient; virtual environment; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2TWZGZ6Q,journalArticle,2017,"Choi, Sung Eun; Brandeau, Margaret L.; Basu, Sanjay",Dynamic treatment selection and modification for personalised blood pressure therapy using a Markov decision process model: a cost-effectiveness analysis.,BMJ open,,2044-6055 2044-6055,10.1136/bmjopen-2017-018374,,"OBJECTIVE: Personalised medicine seeks to select and modify treatments based on individual patient characteristics and preferences. We sought to develop an automated strategy to select and modify blood pressure treatments, incorporating the likelihood that patients with different characteristics would benefit from different types of medications and dosages and the potential severity and impact of different side effects among patients with different characteristics. DESIGN, SETTING AND PARTICIPANTS: We developed a Markov decision process (MDP) model to incorporate meta-analytic data and estimate the optimal treatment for maximising discounted lifetime quality-adjusted life-years (QALYs) based on individual patient characteristics, incorporating medication adjustment choices when a patient incurs side effects. We compared the MDP to current US blood pressure treatment guidelines (the Eighth Joint National Committee, JNC8) and a variant of current guidelines that incorporates results of a major recent trial of intensive treatment (Intensive JNC8). We used a microsimulation model of patient demographics, cardiovascular disease risk factors and side effect probabilities, sampling from the National Health and Nutrition Examination Survey (2003-2014), to compare the expected population outcomes from adopting the MDP versus guideline-based strategies. MAIN OUTCOME MEASURES: Costs and QALYs for the",15/11/2017,26/11/2018 12:49,14/04/2020 08:34,,e018374,,11,7,,BMJ Open,,,,,,,,eng,(c) Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.,,,,,,PMID: 29146652 PMCID: PMC5695480,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Adult; Female; Male; Middle Aged; Young Adult; *Models, Economic; Aged; *Markov Chains; *Precision Medicine; Adolescent; Aged, 80 and over; Antihypertensive Agents/*economics; cardiovascular disease; hypertension; Hypertension/*drug therapy; Nutrition Surveys; personalised medicine; Practice Guidelines as Topic; 00; 100; 120",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DR9Y75J6,journalArticle,2017,"Bloem, Bas R.; Rompen, Lonneke; Vries, Nienke M. de; Klink, Ab; Munneke, Marten; Jeurissen, Patrick",ParkinsonNet: A Low-Cost Health Care Innovation With A Systems Approach From The Netherlands.,Health affairs (Project Hope),,1544-5208 0278-2715,10.1377/hlthaff.2017.0832,,"ParkinsonNet, a low-cost innovation to optimize care for patients with Parkinson disease, was developed in 2004 as a network of physical therapists in several regions in the Netherlands. Since that time, the network has achieved full national reach, with 70 regional networks and around 3,000 specifically trained professionals from 12 disciplines. Key elements include the empowerment of professionals who are highly trained and specialized in Parkinson disease, the empowerment of patients by education and consultation, and the empowerment of integrated multidisciplinary teams to better address and manage the disease. Studies have found that the ParkinsonNet approach leads to outcomes that are at least as good as, if not better than, outcomes from usual care. One study found a 50 percent reduction in hip fractures and fewer inpatient admissions. Other studies suggest that ParkinsonNet leads to modest but important cost savings (at least US$439 per patient annually). These cost savings outweigh the costs of building and maintaining the network. Because of ParkinsonNet's success, the program has now spread to several other countries and serves as a model of a successful and scalable frugal innovation.",2017-11,26/11/2018 12:49,14/04/2020 08:34,,1987-1996,,11,36,,Health Aff (Millwood),,,,,,,,eng,,,,,,,PMID: 29137501,,,,Humans; Netherlands; Surveys and Questionnaires; Disease Management; Treatment Outcome; *Cost Savings; *Health Care Costs; Systems Analysis; Patient Care Team; 00; *care networks; *cost containment healthcare; *low-cost innovation; *Parkinson's disease; *ParkinsonNet; *Physical Therapy Specialty/economics/methods; *Referral and Consultation; Parkinson Disease/*therapy; Patient Education as Topic; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 87PFGUYU,journalArticle,2017,"Kalgotra, Pankush; Sharda, Ramesh; Croff, Julie M.",Examining health disparities by gender: A multimorbidity network analysis of electronic medical record.,International journal of medical informatics,,1872-8243 1386-5056,10.1016/j.ijmedinf.2017.09.014,,"PROBLEM: Multimorbidity health disparities have not been well examined by gender. Co-occurring diseases may be mutually deleterious, co-occurring independently, or co-occurring from a common antecedent. Diseases linked by a common antecedent may be caused by biological, behavioral, social, or environmental factors. This paper aims to address the co-occurrences of diseases using network analysis. METHODS: In this study, we identify these multi-morbidities from a large electronic medical record (EMR) containing diagnoses, symptoms and treatment data on more than 22.1 million patients. We create multimorbidity networks from males and females medical records and compare their structural properties. RESULTS: Our macro analysis at the organ-level indicates that females have a stronger multimorbidity network than males. For example, the female multimorbidity network includes six linkages to mental health, wherein the male multimorbidity network includes only two linkages to mental health. The strength of some disease associations between lipid metabolism and chronic heart disorders is stronger in males than females. CONCLUSION: Our multimorbidity network analysis by gender identifies specific differences in disease diagnosis by gender, and presents questions for biological, behavioral, clinical, and policy research.",2017-12,26/11/2018 12:49,14/04/2020 08:34,,22-28,,,108,,Int J Med Inform,,,,,,,,eng,Copyright (c) 2017 Elsevier B.V. All rights reserved.,,,,,,PMID: 29132627,,,,"Humans; Female; Male; United States/epidemiology; Prevalence; *Electronic Health Records; *Healthcare Disparities; 00; *Practice Patterns, Physicians'; *Gender disparity; *Multimorbidity; *Network analysis; Chronic Disease/classification/*epidemiology; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, AAAVL2FE,journalArticle,2018,"Barriere, Paul; Porcu-Buisson, Geraldine; Hamamah, Samir",Cost-Effectiveness Analysis of the Gonadotropin Treatments HP-hMG and rFSH for Assisted Reproductive Technology in France: A Markov Model Analysis.,Applied health economics and health policy,,1179-1896 1175-5652,10.1007/s40258-017-0361-7,,"OBJECTIVES: The objectives of this study were to assess (1) the expected cost of a live birth (LB) after in vitro fertilization with two different gonadotropin treatments [high purified human menopausal gonadotropin (HP-hMG) and recombinant follicle-stimulating hormone (rFSH)] as the single cost variable, and (2) the cost effectiveness of HP-hMG relative to rFSH in the context of the routine practice of assisted reproductive technology (ART) in France. METHODS: A Markov model was developed to simulate the therapeutic management, the in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) courses, and the effects of complications in hypothetical cohorts of 30,000 patients undergoing IVF/ICSI with fresh embryo transfer (up to four attempts) using data from the MERIT and MEGASET clinical trials or from French routine ART practice. RESULTS: The cost per LB was estimated at euro12,145 and at euro14,247 with HP-hMG and rFSH, respectively, using efficacy data from published clinical trials. The resulting incremental cost-effectiveness ratio (ICER) was - euro11,616 per LB.",2018-02,26/11/2018 12:49,14/04/2020 08:34,,65-77,,1,16,,Appl Health Econ Health Policy,,,,,,,,eng,,,,,,,PMID: 29124676,,,,France; Humans; Cost-Benefit Analysis; Health Care Costs; Female; Markov Chains; Drug Costs; Fertilization in Vitro/*economics/methods; Follicle Stimulating Hormone/*economics/therapeutic use; Menotropins/*economics/therapeutic use; Recombinant Proteins/economics/therapeutic use; 00; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, INEK72H4,journalArticle,2018,"Cheng, Adam; Auerbach, Marc; Calhoun, Aaron; Mackinnon, Ralph; Chang, Todd P.; Nadkarni, Vinay; Hunt, Elizabeth A.; Duval-Arnould, Jordan; Peiris, Nicola; Kessler, David","Building a Community of Practice for Researchers: The International Network for Simulation-Based Pediatric Innovation, Research and Education.",Simulation in healthcare : journal of the Society for Simulation in Healthcare,,1559-713X 1559-2332,10.1097/SIH.0000000000000269,,"STATEMENT: The scope and breadth of simulation-based research is growing rapidly; however, few mechanisms exist for conducting multicenter, collaborative research. Failure to foster collaborative research efforts is a critical gap that lies in the path of advancing healthcare simulation. The 2017 Research Summit hosted by the Society for Simulation in Healthcare highlighted how simulation-based research networks can produce studies that positively impact the delivery of healthcare. In 2011, the International Network for Simulation-based Pediatric Innovation, Research and Education (INSPIRE) was formed to facilitate multicenter, collaborative simulation-based research with the aim of developing a community of practice for simulation researchers. Since its formation, the network has successfully completed and published numerous collaborative research projects. In this article, we describe INSPIRE's history, structure, and internal processes with the goal of highlighting the community of practice model for other groups seeking to form a simulation-based research network.",2018-06,26/11/2018 12:49,14/04/2020 08:34,,S28-S34,,3S Suppl 1,13,,Simul Healthc,,,,,,,,eng,,,,,,,PMID: 29117090,,,,Humans; *Cooperative Behavior; Internationality; 00; Simulation Training/*organization & administration; Health Occupations/*education; Multicenter Studies as Topic/*methods; Pediatrics/*education; Research/*organization & administration; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EXFJWRRX,journalArticle,2017,"Etemadi, Manal; Gorji, Hasan Abolghasem; Kangarani, Hannaneh Mohammadi; Ashtarian, Kioomars",Power structure among the actors of financial support to the poor to access health services: Social network analysis approach.,Social science & medicine (1982),,1873-5347 0277-9536,10.1016/j.socscimed.2017.10.026,,"The extent of universal health coverage in terms of financial protection is worrisome in Iran. There are challenges in health policies to guarantee financial accessibility to health services, especially for poor people. Various institutions offer support to ensure that the poor have financial access to health services. The aim of this study is to investigate the relationship network among the institutions active in this field. This study is a policy document analysis. It evaluates the country's legal documents in the field of financial support to the poor for healthcare after the Islamic Revolution in Iran. The researchers looked for the documents on the related websites and referred to the related organizations. The social network analysis approach was chosen for the analysis of the documents. Block-modelling and multi-dimensional scaling (MDS) was used to determine the network structures. The UCINET software was employed to analyse the data. Most the main actors of this network are chosen from the government budget. There is no legal communication and cooperation among some of the actors because of their improper position in the network. Seven blocks have been clustered by CONCOR in terms of the actor's degree of similarity. The social distance among the actors of the seven blocks is very short. Power distribution in the field of financial support to the poor has a fragmented structure; however, it is mainly run by a dominant block consisting of The Supreme Council of Welfare and Social Security, Health Insurance Organization, and the Ministry of Health and Medical Education. The financial support for the poor network involves multiple actors. This variety has created a series of confusions in terms of the type, level, and scope of responsibilities among the actors. The weak presence legislative and regulatory institutions and also non-governmental institutions are the main weak points of this network.",2017-12,26/11/2018 12:49,14/04/2020 08:34,,01-Nov,,,195,,Soc Sci Med,,,,,,,,eng,Copyright (c) 2017 Elsevier Ltd. All rights reserved.,,,,,,PMID: 29096148,,,,Humans; Health Policy; *Social network analysis; Policy Making; Universal Coverage; *Social Support; *Poverty; *Health Services Accessibility; 00; *Financial support; *Financial Support; *Health policymaking; *Power structure; *The poor; Iran; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, SQ5JGU3P,journalArticle,2018,"Braithwaite, Tasanee; Winford, Blaine; Bailey, Henry; Bridgemohan, Petra; Bartholomew, Debra; Singh, Deo; Sharma, Subash; Sharma, Rishi; Silva, Juan Carlos; Gray, Alastair; Ramsewak, Samuel S.; Bourne, Rupert R. A.",Health system dynamics analysis of eyecare services in Trinidad and Tobago and progress towards Vision 2020 Goals.,Health policy and planning,,1460-2237 0268-1080,10.1093/heapol/czx143,,"Avoidable blindness is an important global public health concern. This study aimed to assess Trinidad and Tobago's progress towards achieving the Pan American Health Organization, 'Strategic Framework for Vision 2020: The Right to Sight-Caribbean Region,' indicators through comprehensive review of the eyecare system, in order to facilitate health system priority setting. We administered structured surveys to six stakeholder groups, including eyecare providers, patients and older adult participants in the National Eye Survey of Trinidad and Tobago. We reviewed reports, registers and policy documents, and used a health system dynamics framework to synthesize data. In 2014, the population of 1.3 million were served by a pluralistic eyecare system, which had achieved 14 out of 27 Strategic Framework indicators. The Government provided free primary, secondary and emergency eyecare services, through 108 health centres and 5 hospitals (0.26 ophthalmologists and 1.32 ophthalmologists-in-training per 50 000 population). Private sector optometrists (4.37 per 50 000 population), and ophthalmologists (0.93 per 50 000 population) provided 80% of all eyecare. Only 19.3% of the adult population had private health insurance, revealing significant out-of-pocket expenditure. We identified potential weaknesses in the eyecare system where investment might reduce avoidable blindness. These included a need for more ophthalmic equipment and maintenance in the public sector, national screening programmes for diabetic retinopathy, retinopathy of prematurity and neonatal eye defects, and pathways to ensure timely and equitable access to subspecialized surgery. Eyecare for older adults was responsible for an estimated 9.5% (US$22.6 million) of annual health expenditure. This study used the health system dynamics framework and new data to identify priorities for eyecare system strengthening. We recommend this approach for exploring potential health system barriers to addressing avoidable blindness, and other important public health problems.",01/01/2018,26/11/2018 12:49,14/04/2020 08:34,,70-84,,1,33,,Health Policy Plan,,,,,,,,eng,"(c) The Author 2017. Published by Oxford University Press in association with The London School of Hygiene and Tropical Medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.",,,,,,PMID: 29092057,,,,"Humans; Surveys and Questionnaires; World Health Organization; Adult; Female; Male; Middle Aged; Aged; *Systems Analysis; Aged, 80 and over; public health; primary care; Outpatients; 00; Blindness/prevention & control; costs; Eye Diseases/epidemiology/surgery; health care utilization; Health Expenditures/statistics & numerical data; health professionals; health systems; Ophthalmologists/statistics & numerical data; ophthalmology; Ophthalmology/economics/instrumentation/manpower/*organization & administration; Optometrists/statistics & numerical data; population; survey; Trinidad and Tobago; 100; 1000",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CIGIUMQB,journalArticle,2017,"Angelis, Aris; Montibeller, Gilberto; Hochhauser, Daniel; Kanavos, Panos",Multiple criteria decision analysis in the context of health technology assessment: a simulation exercise on metastatic colorectal cancer with multiple stakeholders in the English setting.,BMC medical informatics and decision making,,1472-6947 1472-6947,10.1186/s12911-017-0524-3,,"BACKGROUND: Multiple criteria decision analysis (MCDA) has appeared as a methodology to address limitations of economic evaluation in health technology assessment (HTA), however there are limited empirical evidence from real world applications. The aim of this study is to test in practice a recently developed MCDA methodological framework known as Advance Value Framework (AVF) through a proof-of-concept case study engaging multiple stakeholders. METHODS: A multi-attribute value theory methodological process was adopted involving problem structuring, model building, model assessment and model appraisal phases. A facilitated decision analysis modelling approach was used as part of a decision conference with thirteen participants. An expanded scope of the National Institute for Health and Care Excellence (NICE) remit acted as the study setting with the use of supplementary value concerns. Second-line biological treatments were evaluated for metastatic colorectal cancer (mCRC) patients having received prior chemotherapy, including cetuximab monotherapy, panitumumab monotherapy and aflibercept in combination with FOLFIRI chemotherapy. Initially 18 criteria attributes were considered spanning four value domains relating to therapeutic impact, safety profile, innovation level and socioeconomic impact. RESULTS: Nine criteria attributes were finally included. Cetuximab scored the highest overall weighted preference value score of 45.7 out of 100, followed by panitumumab with 42.3, and aflibercept plus FOLFIRI with 14.4. The relative weights of the two most important criteria (overall survival and Grade 4 adverse events) added up to more than the relative weight of all other criteria together (52.1%). Main methodological limitation was the lack of comparative clinical effects across treatments and challenges included the selection of ""lower"" and ""higher"" reference levels on criteria attributes, eliciting preferences across attributes where participants had less experience, and ensuring that all attributes possess the right decision theory properties. CONCLUSIONS: This first application of AVF produced transparent rankings for three mCRC treatments based on their value, by assessing an explicit set of evaluation criteria while allowing for the elicitation and construction of participants' value preferences and their trade-offs. It proved it can aid the evaluation process and value communication of the alternative treatments for the group participants. Further research is needed to optimise its use as part of policy-making.",26/10/2017,26/11/2018 12:49,14/04/2020 08:34,,149,,1,17,,BMC Med Inform Decis Mak,,,,,,,,eng,,,,,,,PMID: 29073892 PMCID: PMC5658981,,,,"Humans; Simulation Training; *Cost-Benefit Analysis; *Models, Theoretical; *Decision Support Techniques; England; *Technology Assessment, Biomedical; 00; Advance Value Framework (AVF); Antineoplastic Agents, Immunological/*pharmacology; Colorectal Neoplasms/*drug therapy; Health technology assessment (HTA); Metastatic colorectal cancer (mCRC); Multiple criteria decision analysis (MCDA); National Institute for Health and Care Excellence (NICE); Neoplasm Metastasis/*drug therapy; New medicines; Proof of Concept Study; Value assessment; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, R2JGJJ69,journalArticle,2017,"Morton, Stephen; Pencheon, David; Squires, Neil","Sustainable Development Goals (SDGs), and their implementation: A national global framework for health, development and equity needs a systems approach at every level.",British medical bulletin,,1471-8391 0007-1420,10.1093/bmb/ldx031,,"Introduction: The Sustainable Development Goals (SDGs) are a set of global goals for fair and sustainable health at every level: from planetary biosphere to local community. The aim is to end poverty, protect the planet and ensure that all people enjoy peace and prosperity, now and in the future. Sources of data: The UN has established web-sites to inform the implementation of the SDGs and an Inter-Agency and Expert Group on an Indicator Framework. We have searched for independent commentaries and analysis. Areas of agreement: The goals represent a framework that is scientifically robust, and widely intuitive intended to build upon the progress established by the Millennium Development Goals (MDGs). There is a need for system wide strategic planning to integrate the economic, social and environmental dimensions into policy and actions. Areas of controversy: Many countries have yet to understand the difference between the MDGs and the SDGs, particularly their universality, the huge potential of new data methods to help with their implementation, and the systems thinking that is needed to deliver the vision. The danger is that individual goals may be prioritized without an understanding of the potential positive interactions between goals. Growing points: There is an increasing understanding that sustainable development needs a paradigm shift in our understanding of the interaction between the real economy and quality of life. There would be many social, environmental and economic benefits in changing our current model. Areas timely for developing research: We need to develop systems wide understanding of what supports a healthy environment and the art and science of making change.",01/12/2017,26/11/2018 12:49,14/04/2020 08:35,,81-90,,1,124,,Br Med Bull,,,,,,,,eng,"(c) The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com",,,,,,PMID: 29069332,,,,Humans; Social Responsibility; Quality of Life; *Conservation of Natural Resources; *Global Health; global goals; global health; Goals; Health Equity; implementation; Program Development; sustainable development; Systems Analysis; United Nations; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, U28T3WIB,journalArticle,2017,"Li, Jieyi; Arandjelovic, Ognjen",Intuitive and interpretable visual communication of a complex statistical model of disease progression and risk.,Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference,,1557-170X 1557-170X,10.1109/EMBC.2017.8037782,,"Computer science and machine learning in particular are increasingly lauded for their potential to aid medical practice. However, the highly technical nature of the state of the art techniques can be a major obstacle in their usability by health care professionals and thus, their adoption and actual practical benefit. In this paper we describe a software tool which focuses on the visualization of predictions made by a recently developed method which leverages data in the form of large scale electronic records for making diagnostic predictions. Guided by risk predictions, our tool allows the user to explore interactively different diagnostic trajectories, or display cumulative long term prognostics, in an intuitive and easily interpretable manner.",2017-07,26/11/2018 12:49,14/04/2020 08:34,,4199-4202,,,2017,,Conf Proc IEEE Eng Med Biol Soc,,,,,,,,eng,,,,,,,PMID: 29060823,,,,"Humans; *Software; Models, Statistical; Risk; Disease Progression; User-Computer Interface; 00; Machine Learning; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6VPCU3HB,journalArticle,2017,"DeBrew, Jacqueline Kayler; Hensley-Hannah, Susan",Integrating Gerontology and Community Concepts Through Simulation.,Nursing education perspectives,,1536-5026 1536-5026,10.1097/01.NEP.0000000000000158,,"This article describes an innovative simulation experience for nursing students. Faculty from a community health nursing course and a course in gerontology worked together to provide a comprehensive simulation experience that combined low-fidelity and high-fidelity experiences that provided an integrated learning experience and gave faculty with an opportunity to collaborate to improve outcomes. Student and faculty feedback was overwhelmingly positive. Future plans include incorporating a third didactic course, Leadership and Management, and working with other disciplines to demonstrate interprofessional collaboration.",2017-12,26/11/2018 12:49,14/04/2020 08:34,,360-361,,6,38,,Nurs Educ Perspect,,,,,,,,eng,,,,,,,PMID: 29054104,,,,"Humans; Learning; *Leadership; 00; Students, Nursing; Faculty; Geriatric Nursing/*education; Geriatrics; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9BLIID8R,journalArticle,2017,"Tasillo, Abriana; Salomon, Joshua A.; Trikalinos, Thomas A.; Horsburgh, C. Robert Jr; Marks, Suzanne M.; Linas, Benjamin P.",Cost-effectiveness of Testing and Treatment for Latent Tuberculosis Infection in Residents Born Outside the United States With and Without Medical Comorbidities in a Simulation Model.,JAMA internal medicine,,2168-6114 2168-6106,10.1001/jamainternmed.2017.3941,,"Importance: Testing for and treating latent tuberculosis infection (LTBI) is among the main strategies to achieve TB elimination in the United States. The best approach to testing among non-US born residents, particularly those with comorbid conditions, is uncertain. Objective: To estimate health outcomes, costs, and cost-effectiveness of LTBI testing and treatment among non-US born residents with and without medical comorbidities. Design, Setting, and Participants: Decision analytic tree and Markov cohort simulation model among non-US born residents with no comorbidities, with diabetes, with HIV infection, or with end-stage renal disease (ESRD) using a health care sector perspective with 3% annual discounting. Strategies compared included no testing, tuberculin skin test (TST), interferon gamma release assay (IGRA), confirm positive (initial TST, IGRA only for TST-positive results; both tests positive indicates LTBI), and confirm negative (initial IGRA, then TST for IGRA-negative; any test positive indicates LTBI). All strategies were coupled to treatment with 3 months of self-administered rifapentine and isoniazid. Main Outcomes and Measures: Number needed to test and treat to prevent 1 case of TB reactivation, discounted quality-adjusted life-years (QALYs), discounted lifetime medical costs, and incremental cost-effectiveness ratios (ICERs). Results: Improving health outcomes increased costs, with choice of test dependent on willingness to pay. Strategies ranked by ascending costs and benefits: no testing, confirm positive, TST, IGRA, and confirm negative. The ICERs varied by non-US born patient risk group: patients with no comorbidities, IGRA was likely cost-effective at $83000/QALY; patients with diabetes, both confirm positive ($53000/QALY) and IGRA ($120000/QALY) were likely cost-effective; patients with HIV, confirm negative was clearly preferred ($63000/QALY); and patients with ESRD, no testing was cost-effective. Increased LTBI prevalence and reduced return for TST reading improved IGRA's relative performance. In 10000 probabilistic simulations among non-US born patients with no comorbidities, with diabetes, and with HIV, some form of testing was virtually always cost-effective. These simulations highlight the uncertainty of test choice for non-US born patients with no comorbidities and non-US born patients with diabetes, but strategies including IGRA were preferred in over 60% of simulations for all non-US born populations except those with ESRD. Conclusions and Relevance: Testing for and treating LTBI among non-US born residents with and without selected comorbidities is likely cost-effective except among those with ESRD in whom competing risks of death limit benefits. Strategies including IGRA fell below a $100000/QALY willingness-to-pay threshold for non-US born patients with no comorbidities, patients with diabetes, and patients with HIV.",01/12/2017,26/11/2018 12:49,14/04/2020 08:35,,1755-1764,,12,177,,JAMA Intern Med,,,,,,,,eng,,,,,,,PMID: 29049814 PMCID: PMC5808933,,,,Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Female; Male; Markov Chains; *Emigrants and Immigrants; Antitubercular Agents/economics/therapeutic use; Bayes Theorem; Comorbidity; Decision Trees; Isoniazid/therapeutic use; Latent Tuberculosis/*diagnosis/*drug therapy/*economics/epidemiology; Rifampin/analogs & derivatives/economics/therapeutic use; Tuberculin Test/economics; United States/epidemiology; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DA684YRN,journalArticle,2017,"Martin, Douglas; Bekiaris, Brent; Hansen, Gregory",Mobile emergency simulation training for rural health providers.,Rural and remote health,,1445-6354 1445-6354,10.22605/RRH4057,,"INTRODUCTION: Mobile emergency simulation offers innovative continuing medical educational support to regions that may lack access to such opportunities. Furthermore, satisfaction is a critical element for active learning. Together, the authors evaluated Canadian rural healthcare providers' satisfaction from high fidelity emergency simulation training using a modified motorhome as a mobile education unit (MEU). METHODS: Over a 5-month period, data was collected during 14 educational sessions in nine different southern Manitoban communities. Groups of up to five rural healthcare providers managed emergency simulation cases including polytrauma, severe sepsis, and inferior myocardial infarction with right ventricular involvement, followed by a debrief. Participants anonymously completed a feedback form that contained 11 questions on a five-point Likert scale and six short-answer questions. RESULTS: Data from 131 respondents were analyzed, for a response rate of 75.6%. Respondents included nurses (27.5%), medical residents (26.7%), medical first responders (16.0%), and physicians (12.2%). The median response was 5 for overall quality of learning, development of clinical reasoning skills and decision-making ability, recognition of patient deterioration, and self-reflection. The post-simulation debrief median response was also 5 for summarizing important issues, constructive criticism, and feedback to learn. Respondents also reported that the MEU provided a believable working environment (87.0%, n=114), they had limited or no previous access to high fidelity mannequins (82.7%, n=107), and they had no specific training in crisis resource management or were unfamiliar with the term (92%, n=118). CONCLUSIONS: A high level of satisfaction was reported in rural health providers with mobile emergency simulation. Access to and experience with high fidelity mannequins was limited, suggesting areas for potential educational growth.",2017-09,26/11/2018 12:49,14/04/2020 08:34,,4057,,3,17,,Rural Remote Health,,,,,,,,eng,,,,,,,PMID: 29040811,,,,"Humans; Canada; Clinical Competence; Simulation Training/*methods; *emergency care; Health Personnel/*education; Attitude of Health Personnel; Manikins; 00; Internship and Residency/methods; *Canada; *education; *patient stimulation; *rural health centers; Education, Continuing/*methods; Education, Nursing/methods; Emergency Medical Services/*methods; Emergency Responders/education; Rural Health Services/*organization & administration; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ZMQRRNRF,journalArticle,2018,"Holt-Lunstad, Julianne",Why Social Relationships Are Important for Physical Health: A Systems Approach to Understanding and Modifying Risk and Protection.,Annual review of psychology,,1545-2085 0066-4308,10.1146/annurev-psych-122216-011902,,"Social relationships are adaptive and crucial for survival. This review presents existing evidence indicating that our social connections to others have powerful influences on health and longevity and that lacking social connection qualifies as a risk factor for premature mortality. A systems perspective is presented as a framework by which to move social connection into the realm of public health. Individuals, and health-relevant biological processes, exist within larger social contexts including the family, neighborhood and community, and society and culture. Applying the social ecological model, this review highlights the interrelationships of individuals within groups in terms of understanding both the causal mechanisms by which social connection influences physical health and the ways in which this influence can inform potential intervention strategies. A systems approach also helps identify gaps in our current understanding that may guide future research.",04/01/2018,26/11/2018 12:49,14/04/2020 08:34,,437-458,,,69,,Annu Rev Psychol,,,,,,,,eng,,,,,,,PMID: 29035688,,,,Humans; Risk Factors; Health Status; *social isolation; *Social Support; Social Isolation; *Social Behavior; *Interpersonal Relations; 1; *loneliness; *social connection; *social ecological model; *Social Environment; *social network; *social relationships; Loneliness; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YMBRA2WU,journalArticle,2017,"Alonge, O.; Lin, S.; Igusa, T.; Peters, D. H.",Improving health systems performance in low- and middle-income countries: a system dynamics model of the pay-for-performance initiative in Afghanistan.,Health policy and planning,,1460-2237 0268-1080,10.1093/heapol/czx122,,"System dynamics methods were used to explore effective implementation pathways for improving health systems performance through pay-for-performance (P4P) schemes. A causal loop diagram was developed to delineate primary causal relationships for service delivery within primary health facilities. A quantitative stock-and-flow model was developed next. The stock-and-flow model was then used to simulate the impact of various P4P implementation scenarios on quality and volume of services. Data from the Afghanistan national facility survey in 2012 was used to calibrate the model. The models show that P4P bonuses could increase health workers' motivation leading to higher levels of quality and volume of services. Gaming could reduce or even reverse this desired effect, leading to levels of quality and volume of services that are below baseline levels. Implementation issues, such as delays in the disbursement of P4P bonuses and low levels of P4P bonuses, also reduce the desired effect of P4P on quality and volume, but they do not cause the outputs to fall below baseline levels. Optimal effect of P4P on quality and volume of services is obtained when P4P bonuses are distributed per the health workers' contributions to the services that triggered the payments. Other distribution algorithms such as equal allocation or allocations proportionate to salaries resulted in quality and volume levels that were substantially lower, sometimes below baseline. The system dynamics models served to inform, with quantitative results, the theory of change underlying P4P intervention. Specific implementation strategies, such as prompt disbursement of adequate levels of performance bonus distributed per health workers' contribution to service, increase the likelihood of P4P success. Poorly designed P4P schemes, such as those without an optimal algorithm for distributing performance bonuses and adequate safeguards for gaming, can have a negative overall impact on health service delivery systems.",01/12/2017,26/11/2018 12:49,14/04/2020 08:34,,1417-1426,,10,32,,Health Policy Plan,,,,,,,,eng,(c) The Author 2017. Published by Oxford University Press in association with The London School of Hygiene and Tropical Medicine.,,,,,,PMID: 29029075 PMCID: PMC5886199,,,,"Humans; Surveys and Questionnaires; implementation; *Delivery of Health Care; Health Expenditures; Attitude of Health Personnel; *Program Evaluation; system dynamics model; *Motivation; 1; Developing Countries; Afghanistan; Health Personnel/*economics; health services delivery; low- and middle-income countries; Performance-based financing; Reimbursement, Incentive/*economics; 210",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GZJF3SAY,journalArticle,2018,"Rajasekhar, Bokam; Nambi, Indumathi M.; Govindarajan, Suresh Kumar",Human health risk assessment of ground water contaminated with petroleum PAHs using Monte Carlo simulations: A case study of an Indian metropolitan city.,Journal of environmental management,,1095-8630 0301-4797,10.1016/j.jenvman.2017.09.078,,"Underground pipelines are frequently used to transport petroleum fuels, through industrial as well as residential zones. Chennai is one of the four largest metropolitan cities of India. The region of interest in this study is located in the northern part of the Chennai. Ground water of this area was contaminated with polyaromatic hydrocarbons (PAHs) from the leaking oil storage tanks and pipe lines. Health risk assessment was conducted for exposure to PAHs in the ground water using incremental life time cancer risk (ILCR) models coupled with benzo[a]pyrene toxic equivalent method. The exposure pathways considered in this study were direct water ingestion and dermal contact under residential scenario. Exposure input parameters were transformed to statistical parameters using lognormal/uniform distributions and resultant probabilities of cancer risk were estimated by performing Monte Carlo simulations. Preliminary remediation goals were predicted using the combination of the cancer risk models of all the exposure routes with the consideration of high-safety risk of 1-in-1 million. Results showed that the cancer risk is predominantly contributed (greater than 98%) by dermal exposure than the oral in both adults and children. The total ILCR is found to be greater than a low safety risk of 1-in-10,000 with higher probability percentages (>90%). The 95th percentile values of the risk were presented in order to address the need for remediation. Appropriate remedial and treatment methods for the subject site were proposed. The results of the study will be useful for the regulatory boards and policy makers in India in understanding the actual impact of the contamination on receptors, setting up final remediation goals and deciding on a specific remedial method.",01/01/2018,26/11/2018 12:49,14/04/2020 08:35,,183-191,,,205,,J Environ Manage,,,,,,,,eng,Copyright (c) 2017 Elsevier Ltd. All rights reserved.,,,,,,PMID: 28985597,,,,Humans; Adult; *Risk Assessment; Child; *Monte Carlo Method; India; 00; *Groundwater; *Polycyclic Aromatic Hydrocarbons; Chennai; Cities; Exposure assessment; Ground water; Monte Carlo simulations; Petroleum; Polycyclic aromatic hydrocarbons; Probabilistic health risk assessment; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2QRJHD3G,journalArticle,2017,"Leal, Jose; Khurshid, Waqar; Pagano, Eva; Feenstra, Talitha",Computer simulation models of pre-diabetes populations: a systematic review protocol.,BMJ open,,2044-6055 2044-6055,10.1136/bmjopen-2016-014954,,"INTRODUCTION: Diabetes is a major public health problem and prediabetes (intermediate hyperglycaemia) is associated with a high risk of developing diabetes. With evidence supporting the use of preventive interventions for prediabetes populations and the discovery of novel biomarkers stratifying the risk of progression, there is a need to evaluate their cost-effectiveness across jurisdictions. In diabetes and prediabetes, it is relevant to inform cost-effectiveness analysis using decision models due to their ability to forecast long-term health outcomes and costs beyond the time frame of clinical trials. To support good implementation and reimbursement decisions of interventions in these populations, models should be clinically credible, based on best available evidence, reproducible and validated against clinical data. Our aim is to identify recent studies on computer simulation models and model-based economic evaluations of populations of individuals with prediabetes, qualify them and discuss the knowledge gaps, challenges and opportunities that need to be addressed for future evaluations. METHODS AND ANALYSIS: A systematic review will be conducted in MEDLINE, Embase, EconLit and National Health Service Economic Evaluation Database. We will extract peer-reviewed studies published between 2000 and 2016 that describe computer simulation models of the natural history of individuals with prediabetes and/or decision models to evaluate the impact of interventions, risk stratification and/or screening on these populations. Two reviewers will independently assess each study for inclusion. Data will be extracted using a predefined pro forma developed using best practice. Study quality will be assessed using a modelling checklist. A narrative synthesis of all studies will be presented, focussing on model structure, quality of models and input data, and validation status. ETHICS AND DISSEMINATION: This systematic review is exempt from ethics approval because the work is carried out on published documents. The findings of the review will be disseminated in a related peer-reviewed journal and presented at conferences. REVIEWREGISTRATION NUMBER: CRD42016047228.",05/10/2017,26/11/2018 12:49,14/04/2020 08:34,,e014954,,10,7,,BMJ Open,,,,,,,,eng,(c) Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.,,,,,,PMID: 28982807 PMCID: PMC5640045,,,,"Humans; Cost-Benefit Analysis; *Computer Simulation; health economics; *Research Design; Models, Economic; economic evaluation; diabetes; 00; Checklist; systematic review; decision model; prediabetes; Prediabetic State/diagnosis/*prevention & control; 100; 120",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UIMT29CD,journalArticle,2017,"Lavelle, Mary; Attoe, Chris; Tritschler, Christina; Cross, Sean",Managing medical emergencies in mental health settings using an interprofessional in-situ simulation training programme: A mixed methods evaluation study.,Nurse education today,,1532-2793 0260-6917,10.1016/j.nedt.2017.09.009,,"BACKGROUND: In the UK, people with severe mental illness die up to 20years earlier than the general population, prompting increased focus on physical health in mental illness. However, training for mental health inpatient staff to meet patients' physical health needs has not received the same attention, with physical health training often being reactive and lacking evidence of effectiveness. OBJECTIVES: To evaluate an interprofessional, in situ, simulation training intervention for managing medical deterioration in mental health settings. Investigating the impact of training on: 1. Participants' knowledge, confidence, and attitudes towards managing medical deterioration; and 2. Incident reporting, as an objective index of incident management. Participants' perceptions of the impact on their practice were qualitatively explored. DESIGN: This evaluation employed a mixed-methods pre-post intervention design. PARTICIPANTS & SETTINGS: Fifty-three healthcare professionals participated including: mental health nurses, psychiatrists, healthcare assistants, and activity co-ordinators from two busy psychiatric triage wards in South London, UK. METHODS: The intervention comprised eight half-day sessions delivered weekly across two wards. Structured surveys assessed participants' knowledge, confidence, and attitudes towards medical deterioration pre and post training. Participants' experience of training was qualitatively captured through post-course surveys and focus groups three months post training. Incident reporting rates for seven-month periods pre and post training were compared. RESULTS: Following training, participants showed significant improvement in knowledge (p<0.001), confidence (p<0.001), and attitudes towards (p<0.02) managing medical deterioration. Incident reporting increased by 33% following training. Participants' reported improved confidence in managing medical deterioration, better understanding of effective communication, improved self-reflection and team working, and an increased sense of responsibility for patients' physical health. CONCLUSIONS: Interprofessional, in situ simulation training for medical deterioration yielded promising outcomes for individuals and teams. Simulation is an under-used training modality in mental health, offering a holistic training approach with the potential to provide educational and clinical benefits while supporting workforce resilience.",2017-12,26/11/2018 12:49,14/04/2020 08:34,,103-109,,,59,,Nurse Educ Today,,,,,,,,eng,Copyright (c) 2017 Elsevier Ltd. All rights reserved.,,,,,,PMID: 28968516,,,,Humans; Surveys and Questionnaires; Female; Male; Interprofessional Relations; Focus Groups; Attitude of Health Personnel; Simulation; 00; Mental health; Clinical Competence/*standards; Self Efficacy; Interprofessional education; Emergency Medical Services/methods/*standards/trends; Health Personnel/*education/standards; Healthcare education; London; Medical emergency; Mental Health Services/*standards/trends; Multi-disciplinary teams; Nursing training; Psychiatry; Simulation Training/methods/standards; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ZB4U844C,journalArticle,2017,"Dainelli, Livia; Xu, Tingting; Li, Min; Zimmermann, Diane; Fang, Hai; Wu, Yangfeng; Detzel, Patrick",Cost-effectiveness of milk powder fortified with potassium to decrease blood pressure and prevent cardiovascular events among the adult population in China: a Markov model.,BMJ open,,2044-6055 2044-6055,10.1136/bmjopen-2017-017136,,"OBJECTIVE: To model the long-term cost-effectiveness of consuming milk powder fortified with potassium to decrease systolic blood pressure (SBP) and prevent cardiovascular events. DESIGN: A best case scenario analysis using a Markov model was conducted. PARTICIPANTS: 8.67% of 50-79 year olds who regularly consume milk in China, including individuals with and without a prior diagnosis of hypertension. INTERVENTION: The model simulated the potential impact of a daily intake of two servings of milk powder fortified with potassium (+700 mg/day) vs the consumption of a milk powder without potassium fortification, assuming a market price equal to 0.99 international dollars (intl$; the consumption of a milk powder without potassium fortification, assuming a market price equal to intl$0.99 for the latter and to intl$1.12 for the first (+13.13%). Both deterministic and probabilistic sensitivity analyses were conducted to test the robustness of the results. MAIN OUTCOME MEASURES: Estimates of the incidence of cardiovascular events and subsequent mortality in China were derived from the literature as well as the effect of increasing potassium intake on blood pressure. The incremental cost-effectiveness ratio (ICER) was used to determine the cost-effectiveness of a milk powder fortified with potassium taking into consideration the direct medical costs associated with the cardiovascular events, loss of working days and health utilities impact. RESULTS: With an ICER equal to int$4711.56 per QALY (quality-adjusted life year) in the best case scenario and assuming 100% compliance, the daily consumption of a milk powder fortified with potassium shown to be a cost-effective approach to decrease SBP and reduce cardiovascular events in China. Healthcare savings due to prevention would amount to intl$8.41 billion. Sensitivity analyses showed the robustness of the results. CONCLUSION: Together with other preventive interventions, the consumption of a milk powder fortified with potassium could represent a cost-effective strategy to attenuate the rapid rise in cardiovascular burden among the 50-79 year olds who regularly consume milk in China.",25/09/2017,26/11/2018 12:49,14/04/2020 08:34,,e017136,,9,7,,BMJ Open,,,,,,,,eng,(c) Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.,,,,,,PMID: 28951410 PMCID: PMC5623478,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Middle Aged; Aged; China/epidemiology; Markov Chains; Blood Pressure/drug effects; cardiovascular; Cardiovascular Diseases/*economics/*epidemiology/prevention & control; china; Cost Savings/statistics & numerical data; cost-effectiveness; Dairy Products/*economics; Food, Fortified/*economics; fortification; Health Care Costs/*statistics & numerical data; Incidence; markov model; potassium; Potassium/*administration & dosage/economics; 1; 00; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, AJGIFEEQ,journalArticle,2017,"Grundy, Quinn; Held, Fabian; Bero, Lisa",A Social Network Analysis of the Financial Links Backing Health and Fitness Apps.,American journal of public health,,1541-0048 0090-0036,10.2105/AJPH.2017.303995,,"OBJECTIVES: To identify the major stakeholders in mobile health app development and to describe their financial relationships using social network analysis. METHODS: We conducted a structured content analysis of a purposive sample of prominent health and fitness apps available in November 2015 in the United States, Canada, and Australia. We conducted a social network analysis of apps' developers, investors, other funding sources, and content advisors to describe the financial relationships underpinning health app development. RESULTS: Prominent health and fitness apps are largely developed by private companies based in North America, with an average of 4.7 (SD = 5.5) financial relations, including founders, external investors, acquiring companies, and commercial partnerships. Network analysis revealed a core of 41 sampled apps connected to 415 other entities by 466 financial relations. This core largely comprised apps published by major technology, pharmaceutical, and fashion corporations. About one third of apps named advisors, many of whom had commercial affiliations. CONCLUSIONS: Public health needs to extend its scrutiny and advocacy beyond the health messages contained within apps to understanding commercial influences on health and, when necessary, challenging them.",2017-11,26/11/2018 12:49,14/04/2020 08:34,,1783-1788,,11,107,,Am J Public Health,,,,,,,,eng,,,,,,,PMID: 28933939,,,,Humans; Canada; United States; Australia; *Social Support; *Capital Financing/economics/organization & administration; *Commerce/economics/organization & administration; *Mobile Applications/economics; Drug Industry; Industry/economics/organization & administration; ******To read; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JLXPC3WA,journalArticle,2017,"Patel, Anik R.; Campbell, Jonathon R.; Sadatsafavi, Mohsen; Marra, Fawziah; Johnston, James C.; Smillie, Kirsten; Lester, Richard T.",Burden of non-adherence to latent tuberculosis infection drug therapy and the potential cost-effectiveness of adherence interventions in Canada: a simulation study.,BMJ open,,2044-6055 2044-6055,10.1136/bmjopen-2016-015108,,"OBJECTIVE: Pharmaceutical treatment of latent tuberculosis infection (LTBI) reduces the risk of progression to active tuberculosis (TB); however, poor adherence tempers the protective effect. We aimed to estimate the health burden of non-adherence, the maximum allowable cost of hypothetical new adherence interventions to be cost-effective and the potential value of existing adherence interventions for patients with low-risk LTBI in Canada. DESIGN: A microsimulation model of LTBI progression over 25 years. SETTING: General practice in Canada. PARTICIPANTS: Individuals with LTBI who are initiating drug therapy. INTERVENTIONS: A hypothetical intervention with a range of effectiveness was evaluated. Existing drug adherence interventions including peer support, two-way text messaging support, enhanced adherence counselling and adherence incentives were also evaluated. PRIMARY AND SECONDARY OUTCOME MEASURES: Simulation outcomes included healthcare costs, TB incidence, TB deaths and quality-adjusted life years (QALYs). Base case results were interpreted against a willingness-to-pay threshold of $C50 000/QALY. RESULTS: Compared with current adherence levels, full adherence to LTBI drug therapy could reduce new TB cases from 90.3 cases per 100 000 person-years to 35.9 cases per 100 000 person-years and reduce TB-related deaths from 7.9 deaths per 100 000 person-years to 3.1 deaths per 100 000 person-years. An intervention that increases relative adherence by 40% would bring the population near full adherence to drug therapy and could have a maximum allowable annual cost of approximately $C450 per person to be cost-effective. Based on estimates of effect sizes and costs of existing adherence interventions, we found that they yielded between 900 and 2400 additional QALYs per million people, reduced TB deaths by 5%-25% and were likely to be cost-effective over 25 years. CONCLUSION: Full adherence could reduce the number of future TB cases by nearly 60%, offsetting TB-related costs and health burden. Several existing interventions are could be cost-effective to help achieve this goal.",15/09/2017,26/11/2018 12:49,14/04/2020 08:35,,e015108,,9,7,,BMJ Open,,,,,,,,eng,(c) Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.,,,,,,PMID: 28918407 PMCID: PMC5640098,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; cost-effectiveness; Health Care Costs/*statistics & numerical data; Incidence; adherence interventions; Antitubercular Agents/*economics/therapeutic use; burden of disease; Canada/epidemiology; Cost of Illness; health economics; Latent Tuberculosis/drug therapy/*economics/*mortality; Medication Adherence/*statistics & numerical data; Models, Theoretical; public health; Text Messaging; tuberculosis; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3NLWLY2X,journalArticle,2017,"Gittins Stone, Daniel Ian; DuBois, Russell; DeJesus, Brett; Rodgers, Rachel F.; Rizzo, Christie",Brief report: A network analysis of self-cutting risk among late adolescent girls exposed to dating violence.,Journal of adolescence,,1095-9254 0140-1971,10.1016/j.adolescence.2017.09.002,,"Adolescent self-directed violence (SDV) is a major public health concern. Adolescent girls exposed to dating violence (DV) are a particularly vulnerable group. Numerous studies have examined the number and type of SDV risk factors, but few examined global patterns of relationships among them. Exploring global patterns of risk is crucial to developing targeted prevention efforts. In this study we applied a network model to identify risk patterns for a common form of SDV, self-cutting, among American adolescent girls (N = 109) with history of DV. Risk factor networks were compared among girls who did/did not endorse lifetime self-cutting. Girls with a history of self-cutting (19%) had a risk factor network characterized by a higher number of associations than girls who did not (test statistic = 0.142; 95% CI = 02-.03). For these girls, the experience of one risk factor is more likely to co-occur with multiple others, thereby potentially compounding effects and unwanted consequences.",2017-12,26/11/2018 12:49,14/04/2020 08:34,,Dec-16,,,61,,J Adolesc,,,,,,,,eng,Copyright (c) 2017 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.,,,,,,PMID: 28910672,,,,Humans; Surveys and Questionnaires; Female; Risk Factors; Adolescent; Cross-Sectional Studies; 00; Network analysis; Adolescent self-directed violence; Case-Control Studies; Dating violence; Intimate Partner Violence/*psychology/statistics & numerical data; Self-cutting; Self-Injurious Behavior/*etiology/psychology; Suicide risk; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DR92RPY5,journalArticle,2017,"Ishikawa, Tomoki; Fujiwara, Kensuke; Ohba, Hisateru; Suzuki, Teppei; Ogasawara, Katsuhiko",Forecasting the regional distribution and sufficiency of physicians in Japan with a coupled system dynamics-geographic information system model.,Human resources for health,,1478-4491 1478-4491,10.1186/s12960-017-0238-8,,"BACKGROUND: In Japan, the shortage of physicians has been recognized as a major medical issue. In our previous study, we reported that the absolute shortage will be resolved in the long term, but maldistribution among specialties will persist. To address regional shortage, several Japanese medical schools increased existing quota and established ""regional quotas."" This study aims to assist policy makers in designing effective policies; we built a model for forecasting physician numbers by region to evaluate future physician supply-demand balances. METHODS: For our case study, we selected Hokkaido Prefecture in Japan, a region displaying disparities in healthcare services availability between urban and rural areas. We combined a system dynamics (SD) model with geographic information system (GIS) technology to analyze the dynamic change in spatial distribution of indicators. For Hokkaido overall and for each secondary medical service area (SMSA) within the prefecture, we analyzed the total number of practicing physicians. For evaluating absolute shortage and maldistribution, we calculated sufficiency levels and Gini coefficient. Our study covered the period 2010-2030 in 5-year increments. RESULTS: According to our forecast, physician shortage in Hokkaido Prefecture will largely be resolved by 2020. Based on current policies, we forecast that four SMSAs in Hokkaido will continue to experience physician shortages past that date, but only one SMSA would still be understaffed in 2030. CONCLUSION: The results show the possibility that diminishing imbalances between SMSAs would not necessarily mean that regional maldistribution would be eliminated, as seen from the sufficiency levels of the various SMSAs. Urgent steps should be taken to place doctors in areas where our forecasting model predicts that physician shortages could occur in the future.",12/09/2017,26/11/2018 12:49,14/04/2020 08:34,,64,,1,15,,Hum Resour Health,,,,,,,,eng,,,,,,,PMID: 28899406 PMCID: PMC5596465,,,,"*Health Policy; Humans; Forecasting; *Forecasting; Japan; *Physicians; *Healthcare Disparities; *Health Services Accessibility; *Rural Population; 00; *Education, Medical; *Maldistribution; *Physician shortage; *System dynamics; Geographic Information Systems; Physicians/*supply & distribution; Rural Health Services/*manpower; Schools, Medical; Urban Population; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KV773ZAF,journalArticle,2017,"Soccio, Denise A.",Effectiveness of Mental Health Simulation in Replacing Traditional Clinical Hours in Baccalaureate Nursing Education.,Journal of psychosocial nursing and mental health services,,0279-3695 0279-3695,10.3928/02793695-20170905-03,,"The purpose of the current study was to (a) determine whether baccalaureate nursing students receiving mental health simulation as a replacement for 25% of traditional clinical hours have equivalent or greater mental health knowledge and self-confidence compared to those who did not receive this simulation; and (b) explore students' perceptions of their mental health simulation compared to traditional clinical hours. An evidence-based practice pilot study was conducted using a mixed-methods design. Quantitative data demonstrated that students who received mental health simulation as a replacement for 25% of traditional clinical hours have equivalent mental health knowledge and self-confidence as those who did not receive the simulation. Qualitative data indicated students found the simulation helpful in learning how to manage patient behaviors. The current study provides substantial evidence that simulation can be used as a replacement for 25% of traditional clinical hours in mental health nursing. [Journal of Psychosocial Nursing and Mental Health Services, 55(11), 36-43.].",01/11/2017,26/11/2018 12:49,14/04/2020 08:35,,36-43,,11,55,,J Psychosoc Nurs Ment Health Serv,,,,,,,,eng,"Copyright 2017, SLACK Incorporated.",,,,,,PMID: 28892552,,,,"Humans; Surveys and Questionnaires; Female; Learning; Male; Young Adult; Students, Nursing/*psychology; Simulation Training/*methods; *Clinical Competence; *Self Efficacy; Education, Nursing, Baccalaureate; Pilot Projects; Psychiatric Nursing/*education; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QNBP3U2J,journalArticle,2017,"Anderson, Gillian H.; Jenkins, Paul J.; McDonald, David A.; Van Der Meer, Robert; Morton, Alec; Nugent, Margaret; Rymaszewski, Lech A.",Cost comparison of orthopaedic fracture pathways using discrete event simulation in a Glasgow hospital.,BMJ open,,2044-6055 2044-6055,10.1136/bmjopen-2016-014509,,"OBJECTIVE: Healthcare faces the continual challenge of improving outcome while aiming to reduce cost. The aim of this study was to determine the micro cost differences of the Glasgow non-operative trauma virtual pathway in comparison to a traditional pathway. DESIGN: Discrete event simulation was used to model and analyse cost and resource utilisation with an activity-based costing approach. Data for a full comparison before the process change was unavailable so we used a modelling approach, comparing a virtual fracture clinic (VFC) with a simulated traditional fracture clinic (TFC). SETTING: The orthopaedic unit VFC pathway pioneered at Glasgow Royal Infirmary has attracted significant attention and interest and is the focus of this cost study. OUTCOME MEASURES: Our study focused exclusively on patients with non-operative trauma attending emergency department or the minor injuries unit and the subsequent step in the patient pathway. Retrospective studies of patient outcomes as a result of the protocol introductions for specific injuries are presented in association with activity costs from the models. RESULTS: Patients are satisfied with the new pathway, the information provided and the outcome of their injuries (Evidence Level IV). There was a 65% reduction in the number of first outpatient face-to-face (f2f) attendances in orthopaedics. In the VFC pathway, the resources required per day were significantly lower for all staff groups (p/=3.25%. Offering a choice of influenza vaccines, with reasonable resultant increases in coverage, decreased influenza cases by >100,000 with a favorable cost-effectiveness profile. Clinical trials testing the predictions made based on these simulation results and deliberation of policies and procedures to facilitate choice should be considered.",01/05/2017,26/11/2018 12:49,14/04/2020 08:34,,822-831,,9,185,,Am J Epidemiol,,,,,,,,eng,"(c) The Author 2017. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.",,,,,,PMID: 28402385 PMCID: PMC5411677,,,,"Humans; United States; Cost-Benefit Analysis; Adult; Female; Male; Middle Aged; Young Adult; *Public Health; Aged; Child; *agent-based modeling; Adolescent; Aged, 80 and over; Cost of Illness; Child, Preschool; Infant; *cost-effectiveness; *influenza; *influenza vaccine; *vaccine choice; Centers for Disease Control and Prevention (U.S.); Epidemiologic Methods; Health Expenditures; Immunization Programs/*economics; Influenza Vaccines/*administration & dosage/*economics/immunology; Models, Econometric; 1; Agent Based; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, P4CXU2JZ,journalArticle,2017,"Parisi, Thomas J.; Konopka, Joseph F.; Bedair, Hany S.",What is the Long-term Economic Societal Effect of Periprosthetic Infections After THA? A Markov Analysis.,Clinical orthopaedics and related research,,1528-1132 0009-921X,10.1007/s11999-017-5333-6,,"BACKGROUND: Current estimates for the direct costs of a single episode of care for periprosthetic joint infection (PJI) after THA are approximately USD 100,000. These estimates do not account for the costs of failed treatments and do not include indirect costs such as lost wages. QUESTIONS/PURPOSES: The goal of this study was to estimate the long-term economic effect to society (direct and indirect costs) of a PJI after THA treated with contemporary standards of care in a hypothetical patient of working age (three scenarios, age 55, 60, and 65 years). METHODS: We created a state-transition Markov model with health states defined by surgical treatment options including irrigation and debridement with modular exchange, single-stage revision, and two-stage revision. Reoperation rates attributable to septic and aseptic failure modes and indirect and direct costs were calculated estimates garnered via multiple systematic reviews of peer-reviewed orthopaedic and infectious disease journals and Medicare reimbursement data. We conducted an analysis over a hypothetical patient's lifetime from the societal perspective with costs discounted by 3% annually. We conducted sensitivity analysis to delineate the effects of uncertainty attributable to input variables. RESULTS: The model found a base case cost of USD 390,806 per 65-year-old patient with an infected THA. One-way sensitivity analysis gives a range of USD 389,307 (65-year-old with a 3% reinfection rate) and USD 474,004 (55-year-old with a 12% reinfection rate). Indirect costs such as lost wages make up a considerable portion of the costs and increase considerably as age at the time of infection decreases. CONCLUSIONS: The results of this study show that the overall treatment of a periprosthetic infection after a THA is markedly more expensive to society than previously estimated when accounting for the considerable failure rates of current treatment options and including indirect costs. These overall costs, combined with a large projected increase in THAs and a steady state of septic failures, should be taken into account when considering the total cost of THA. Further research is needed to adequately compare the clinical and economic effectiveness of alternative treatment pathways. LEVEL OF EVIDENCE: Level II, economic and decision analysis.",2017-07,26/11/2018 12:49,14/04/2020 08:35,,1891-1900,,7,475,,Clin Orthop Relat Res,,,,,,,,eng,,,,,,,PMID: 28389865 PMCID: PMC5449335,,,,"Humans; Female; Male; Middle Aged; Aged; Markov Chains; Cost of Illness; 00; *Arthroplasty, Replacement, Hip; Episode of Care; Prosthesis-Related Infections/*economics/*therapy; Reoperation/economics; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HSZ4EJQJ,journalArticle,2017,"Hunter, Amanda L.; Shah, Anoop S. V.; Langrish, Jeremy P.; Raftis, Jennifer B.; Lucking, Andrew J.; Brittan, Mairi; Venkatasubramanian, Sowmya; Stables, Catherine L.; Stelzle, Dominik; Marshall, James; Graveling, Richard; Flapan, Andrew D.; Newby, David E.; Mills, Nicholas L.",Fire Simulation and Cardiovascular Health in Firefighters.,Circulation,,1524-4539 0009-7322,10.1161/CIRCULATIONAHA.116.025711,,"BACKGROUND: Rates of myocardial infarction in firefighters are increased during fire suppression duties, and are likely to reflect a combination of factors including extreme physical exertion and heat exposure. We assessed the effects of simulated fire suppression on measures of cardiovascular health in healthy firefighters. METHODS: In an open-label randomized crossover study, 19 healthy firefighters (age, 41+/-7 years; 16 males) performed a standardized training exercise in a fire simulation facility or light duties for 20 minutes. After each exposure, ex vivo thrombus formation, fibrinolysis, platelet activation, and forearm blood flow in response to intra-arterial infusions of endothelial-dependent and -independent vasodilators were measured. RESULTS: After fire simulation training, core temperature increased (1.0+/-0.1 degrees C) and weight reduced (0.46+/-0.14 kg, P<0.001 for both). In comparison with control, exposure to fire simulation increased thrombus formation under low-shear (73+/-14%) and high-shear (66+/-14%) conditions (P<0.001 for both) and increased platelet-monocyte binding (7+/-10%, P=0.03). There was a dose-dependent increase in forearm blood flow with all vasodilators (P<0.001), which was attenuated by fire simulation in response to acetylcholine (P=0.01) and sodium nitroprusside (P=0.004). This was associated with a rise in fibrinolytic capacity, asymptomatic myocardial ischemia, and an increase in plasma cardiac troponin I concentrations (1.4 [0.8-2.5] versus 3.0 [1.7-6.4] ng/L, P=0.010). CONCLUSIONS: Exposure to extreme heat and physical exertion during fire suppression activates platelets, increases thrombus formation, impairs vascular function, and promotes myocardial ischemia and injury in healthy firefighters. Our findings provide pathogenic mechanisms to explain the association between fire suppression activity and acute myocardial infarction in firefighters. CLINICAL TRIAL REGISTRATION: URL: http://www.clinicaltrials.gov. Unique identifier: NCT01812317.",04/04/2017,26/11/2018 12:49,14/04/2020 08:34,,1284-1295,,14,135,,Circulation,,,,,,,,eng,(c) 2017 The Authors.,,,,,,PMID: 28373523 PMCID: PMC5377985,,,,"Humans; Female; Male; Cross-Over Studies; 00; *endothelium-dependent relaxation; *firefighters; *Firefighters; *thrombosis; *vascular; Cardiovascular Diseases/*etiology; Endothelium, Vascular/*physiopathology; Fires; Thrombosis/*physiopathology; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JFXUZKFK,journalArticle,2017,"Mooney, Mitchell; Charlton, Paula C.; Soltanzadeh, Sadjad; Drew, Michael K.",Who 'owns' the injury or illness? Who 'owns' performance? Applying systems thinking to integrate health and performance in elite sport.,British journal of sports medicine,,1473-0480 0306-3674,10.1136/bjsports-2016-096649,,,2017-07,26/11/2018 12:49,14/04/2020 08:35,,1054-1055,,14,51,,Br J Sports Med,,,,,,,,eng,,,,,,,PMID: 28330847,,,,Humans; *Systems Analysis; systems thinking; Sports; performance; 00; health systems; *Athletic Injuries; *Athletic Performance; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VQPEB782,journalArticle,2017,"Achoki, Tom; Lesego, Abaleng","The imperative for systems thinking to promote access to medicines, efficient delivery, and cost-effectiveness when implementing health financing reforms: a qualitative study.",International journal for equity in health,,1475-9276 1475-9276,10.1186/s12939-017-0550-x,,"BACKGROUND: Health systems across Africa are faced with a multitude of competing priorities amidst pressing resource constraints. Expansion of health insurance coverage offers promise in the quest for sustainable healthcare financing for many of the health systems in the region. However, the broader policy implications of expanding health insurance coverage have not been fully investigated and contextualized to many African health systems. METHODS: We interviewed 37 key informants drawn from public, private and civil society organizations involved in health service delivery in Botswana. The objective was to determine the potential health system impacts that would result from expanding the health insurance scheme covering public sector employees. Study participants were selected through purposeful sampling, stakeholder mapping, and snowballing. We thematically synthesized their views, focusing on the key health system areas of access to medicines, efficiency and cost-effectiveness, as intermediate milestones towards universal health coverage. RESULTS: Participants suggested that expansion of health insurance would be characterized by increased financial resources for health and catalyze an upsurge in utilization of health services particularly among those with health insurance cover. As a result, the health system, particularly within the private sector, would be expected to see higher demand for medicines and other health technologies. However, majority of the respondents cautioned that, realizing the full benefits of improved population health, equitable distribution and financial risk protection, would be wholly dependent on having sound policies, regulations and functional accountability systems in place. It was recommended that, health system stewards should embrace efficient and cost-effective delivery, in order to make progress towards universal health coverage. CONCLUSION: Despite the prospects of increasing financial resources available for health service delivery, expansion of health insurance also comes with many challenges. Decision-makers keen to achieve universal health coverage, must view health financing reform through the holistic lens of the health system and its interactions with the population, in order to anticipate its potential benefits and risks. Failure to embrace this comprehensive approach, would potentially lead to counterproductive results.",21/03/2017,26/11/2018 12:49,14/04/2020 08:34,,53,,1,16,,Int J Equity Health,,,,,,,,eng,,,,,,,PMID: 28327143 PMCID: PMC5361842,,,,"Humans; Cost-Benefit Analysis; Qualitative Research; *Systems Analysis; *Efficiency; *Access to medicines; *Health financing; *Health insurance; *Health systems; *Healthcare Financing; Africa; Efficiency, Organizational; Health Care Reform/economics/*organization & administration; Health Services Accessibility/*organization & administration; Insurance, Health/organization & administration; Pharmaceutical Preparations/supply & distribution; Universal Coverage; 00; 100; 120",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YABA6AQ2,journalArticle,2017,"Hunt, Elizabeth A.; Duval-Arnould, Jordan M.; Chime, Nnenna O.; Jones, Kareen; Rosen, Michael; Hollingsworth, Merona; Aksamit, Deborah; Twilley, Marida; Camacho, Cheryl; Nogee, Daniel P.; Jung, Julianna; Nelson-McMillan, Kristen; Shilkofski, Nicole; Perretta, Julianne S.","Integration of in-hospital cardiac arrest contextual curriculum into a basic life support course: a randomized, controlled simulation study.",Resuscitation,,1873-1570 0300-9572,10.1016/j.resuscitation.2017.03.014,,"OBJECTIVE: The objective was to compare resuscitation performance on simulated in-hospital cardiac arrests after traditional American Heart Association (AHA) Healthcare Provider Basic Life Support course (TradBLS) versus revised course including in-hospital skills (HospBLS). DESIGN: This study is a prospective, randomized, controlled curriculum evaluation. SETTING: Johns Hopkins Medicine Simulation Center. SUBJECTS: One hundred twenty-two first year medical students were divided into fifty-nine teams. INTERVENTION: HospBLS course of identical length, containing additional content contextual to hospital environments, taught utilizing Rapid Cycle Deliberate Practice (RCDP). MEASUREMENTS: The primary outcome measure during simulated cardiac arrest scenarios was chest compression fraction (CCF) and secondary outcome measures included metrics of high quality resuscitation. MAIN RESULTS: Out-of-hospital cardiac arrest HospBLS teams had larger CCF: [69% (65-74) vs. 58% (53-62), p<0.001] and were faster than TradBLS at initiating compressions: [median (IQR): 9s (7-12) vs. 22s (17.5-30.5), p<0.001]. In-hospital cardiac arrest HospBLS teams had larger CCF: [73% (68-75) vs. 50% (43-54), p<0.001] and were faster to initiate compressions: [10s (6-11) vs. 36s (27-63), p<0.001]. All teams utilized the hospital AED to defibrillate within 180s per AHA guidelines [HospBLS: 122s (103-149) vs. TradBLS: 139s (117-172), p=0.09]. HospBLS teams performed more hospital-specific maneuvers to optimize compressions, i.e. utilized: CPR button to flatten bed: [7/30 (23%) vs. 0/29 (0%), p=0.006], backboard: [21/30 (70%) vs. 5/29 (17%), p<0.001], stepstool: [28/30 (93%) vs. 8/29 (28%), p<0.001], lowered bedrails: [28/30 (93%) vs. 10/29 (34%), p<0.001], connected oxygen appropriately: [26/30 (87%) vs. 1/29 (3%), p<0.001] and used oral airway and/or two-person bagging when traditional bag-mask-ventilation unsuccessful: [30/30 (100%) vs. 0/29 (0%), p<0.001]. CONCLUSION: A hospital focused BLS course utilizing RCDP was associated with improved performance on hospital-specific quality measures compared with the traditional AHA course.",2017-05,26/11/2018 12:49,14/04/2020 08:34,,127-132,,,114,,Resuscitation,,,,,,,,eng,Copyright (c) 2017. Published by Elsevier B.V.,,,,,,PMID: 28323084,,,,"Humans; Female; Male; Curriculum; Simulation Training/*methods; Heart Arrest/*therapy; *Education; *Simulation; Time Factors; Prospective Studies; Heart Massage/*standards; 00; Students, Medical; *Cardiac arrest; *Cardiopulmonary resuscitation; *Teamwork; *Time sensitive; Cardiopulmonary Resuscitation/*education/standards; Electric Countershock/*methods; Out-of-Hospital Cardiac Arrest/*therapy; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BX3FSMX6,journalArticle,2017,"Gao, Kaifu; Zhao, Yunjie",A Network of Conformational Transitions in the Apo Form of NDM-1 Enzyme Revealed by MD Simulation and a Markov State Model.,The journal of physical chemistry. B,,1520-5207 1520-5207,10.1021/acs.jpcb.7b00062,,"New Delhi metallo-beta-lactamase-1 (NDM-1) is a novel beta-lactamase enzyme that confers enteric bacteria with nearly complete resistance to all beta-lactam antibiotics, so it raises a formidable and global threat to human health. However, the binding mechanism between apo-NDM-1 and antibiotics as well as related conformational changes remains poorly understood, which largely hinders the overcoming of its antibiotic resistance. In our study, long-time conventional molecular dynamics simulation and Markov state models were applied to reveal both the dynamical and conformational landscape of apo-NDM-1: the MD simulation demonstrates that loop L3, which is responsible for antibiotic binding, is the most flexible and undergoes dramatic conformational changes; moreover, the Markov state model built from the simulation maps four metastable states including open, semiopen, and closed conformations of loop L3 as well as frequent transitions between the states. Our findings propose a possible conformational selection model for the binding mechanism between apo-NDM-1 and antibiotics, which facilitates the design of novel inhibitors and antibiotics.",13/04/2017,26/11/2018 12:49,14/04/2020 08:34,,2952-2960,,14,121,,J Phys Chem B,,,,,,,,eng,,,,,,,PMID: 28319394,,,,Humans; *Markov Chains; 00; *Molecular Dynamics Simulation; beta-Lactamases/*chemistry/metabolism; Protein Conformation; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, I44BIR8A,journalArticle,2016,"Myneni, Sahiti; Cobb, Nathan K.; Cohen, Trevor",Content-specific network analysis of peer-to-peer communication in an online community for smoking cessation.,AMIA ... Annual Symposium proceedings. AMIA Symposium,,1942-597X 1559-4076,,,"Analysis of user interactions in online communities could improve our understanding of health-related behaviors and inform the design of technological solutions that support behavior change. However, to achieve this we would need methods that provide granular perspective, yet are scalable. In this paper, we present a methodology for high-throughput semantic and network analysis of large social media datasets, combining semi-automated text categorization with social network analytics. We apply this method to derive content-specific network visualizations of 16,492 user interactions in an online community for smoking cessation. Performance of the categorization system was reasonable (average",2016,26/11/2018 12:49,14/04/2020 08:35,,934-943,,,2016,,AMIA Annu Symp Proc,,,,,,,,eng,,,,,,,PMID: 28269890 PMCID: PMC5333292,,,,Humans; Reproducibility of Results; *Communication; *Social Support; *Interpersonal Relations; Peer Group; Internet; Semantics; 00; *Social Media; *Smoking Cessation/methods/psychology; Datasets as Topic; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8Q4VQ52W,journalArticle,2017,"Requena-Mendez, Ana; Bussion, Sheila; Aldasoro, Edelweiss; Jackson, Yves; Angheben, Andrea; Moore, David; Pinazo, Maria-Jesus; Gascon, Joaquim; Munoz, Jose; Sicuri, Elisa",Cost-effectiveness of Chagas disease screening in Latin American migrants at primary health-care centres in Europe: a Markov model analysis.,The Lancet. Global health,,2214-109X 2214-109X,10.1016/S2214-109X(17)30073-6,,"BACKGROUND: Chagas disease is currently prevalent in European countries hosting large communities from Latin America. Whether asymptomatic individuals at risk of Chagas disease living in Europe should be screened and treated accordingly is unclear. We performed an economic evaluation of systematic Chagas disease screening of the Latin American population attending primary care centres in Europe. METHODS: We constructed a decision tree model that compared the test option (screening of asymptomatic individuals, treatment, and follow-up of positive cases) with the no-test option (screening, treating, and follow-up of symptomatic individuals). The decision tree included a Markov model with five states, related to the chronic stage of the disease: indeterminate, cardiomyopathy, gastrointestinal, response to treatment, and death. The model started with a target population of 100 000 individuals, of which 4.2% (95% CI 2.2-6.8) were estimated to be infected by Trypanosoma cruzi. The primary outcome was the incremental cost-effectiveness ratio (ICER) between test and no-test options. Deterministic and probabilistic analyses (Monte Carlo simulations) were performed. FINDINGS: In the deterministic analysis, total costs referred to 100 000 individuals in the test and no-test option were euro30 903 406 and euro6 597 403 respectively, with a difference of euro24 306 003. The respective number of quality-adjusted life-years (QALYs) gained in the test and no-test option were 61 820.82 and 57 354.42. The ICER was euro5442. In the probabilistic analysis, total costs for the test and no-test option were euro32 163 649 (95% CI 31 263 705-33 063 593) and euro6 904 764 (6 703 258-7 106 270), respectively. The respective number of QALYs gained was 64 634.35 (95% CI 62 809.6-66 459.1) and 59 875.73 (58 191.18-61 560.28). The difference in QALYs gained between the test and no test options was 4758.62 (95% CI 4618.42-4898.82). The incremental cost-effectiveness ratio (ICER) was euro6840.75 (95% CI 2545-2759) per QALY gained for a treatment efficacy of 20% and euro4243 per QALY gained for treatment efficacy of 50%. Even with a reduction in Chagas disease prevalence to 0.05% and with large variations in all the parameters, the test option would still be more cost-effective than the no-test option (less than euro30000 per QALY). INTERPRETATION: Screening for Chagas disease in asymptomatic Latin American adults living in Europe is a cost-effective strategy. Findings of our model provide an important element to support the implementation of T cruzi screening programmes at primary health centres in European countries hosting Latin American migrants. FUNDING: European Commission 7th Framework Program.",2017-04,26/11/2018 12:49,14/04/2020 08:35,,e439-e447,,4,5,,Lancet Glob Health,,,,,,,,eng,Copyright (c) 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license. Published by Elsevier Ltd.. All rights reserved.,,,,,,PMID: 28256340,,,,Humans; Cost-Benefit Analysis; Female; Male; Antiprotozoal Agents/economics; Chagas Disease/diagnosis/*economics/*ethnology; Emigrants and Immigrants/*statistics & numerical data; Europe/epidemiology; Latin America/ethnology; Mass Screening/*economics/statistics & numerical data; Primary Health Care/*economics/organization & administration; 00; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EKYGRT26,journalArticle,2017,"Wagner, Michael; Mileder, Lukas P.; Goeral, Katharina; Klebermass-Schrehof, Katrin; Cardona, Francesco S.; Berger, Angelika; Schmolzer, Georg M.; Olischar, Monika",Student peer teaching in paediatric simulation training is a feasible low-cost alternative for education.,"Acta paediatrica (Oslo, Norway : 1992)",,1651-2227 0803-5253,10.1111/apa.13792,,"AIM: The World Health Organization recommends regular simulation training to prevent adverse healthcare events. We used specially trained medical students to provide paediatric simulation training to their peers and assessed feasibility, cost and confidence of students who attended the courses. METHODS: Students at the Medical University of Vienna, Austria were eligible to participate. Students attended two high-fidelity simulation training sessions, delivered by peers, which were videorecorded for evaluation. The attendees then completed questionnaires before and after the training. Associated costs and potential benefits were analysed. RESULTS: From May 2013 to June 2015, 152 students attended the sessions and 57 (37.5%) completed both questionnaires. Satisfaction was high, with 95% stating their peer tutor was competent and 90% saying that peer tutors were well prepared. The attendees' confidence in treating critically ill children significantly improved after training (p < 0.001). The average costs for a peer tutor were six Euros per working hour, compared to 35 Euros for a physician. CONCLUSION: Using peer tutors for paediatric simulation training was a feasible and low-cost option that increased the number of medical students who could be trained and increased the self-confidence of the attendees. Satisfaction with the peer tutors was high.",2017-06,26/11/2018 12:49,14/04/2020 08:35,,995-1000,,6,106,,Acta Paediatr,,,,,,,,eng,(c)2017 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.,,,,,,PMID: 28244140,,,,"Humans; Female; Male; Simulation Training/*economics; Peer Group; Emergency Medical Services; 00; Students, Medical/*psychology; Pediatrics/*education; Education, Medical/*methods; Adverse healthcare events; Medical students; Paediatric simulation training; Peer tutors; Teaching/*organization & administration; Training costs; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Y6BUGR8P,journalArticle,2017,"Hernandez, Alison; Ruano, Ana Lorena; Marchal, Bruno; San Sebastian, Miguel; Flores, Walter",Engaging with complexity to improve the health of indigenous people: a call for the use of systems thinking to tackle health inequity.,International journal for equity in health,,1475-9276 1475-9276,10.1186/s12939-017-0521-2,,"The 400 million indigenous people worldwide represent a wealth of linguistic and cultural diversity, as well as traditional knowledge and sustainable practices that are invaluable resources for human development. However, indigenous people remain on the margins of society in high, middle and low-income countries, and they bear a disproportionate burden of poverty, disease, and mortality compared to the general population. These inequalities have persisted, and in some countries have even worsened, despite the overall improvements in health indicators in relation to the 15-year push to meet the Millennium Development Goals. As we enter the Sustainable Development Goals (SDGs) era, there is growing consensus that efforts to achieve Universal Health Coverage (UHC) and promote sustainable development should be guided by the moral imperative to improve equity. To achieve this, we need to move beyond the reductionist tendency to frame indigenous health as a problem of poor health indicators to be solved through targeted service delivery tactics and move towards holistic, integrated approaches that address the causes of inequalities both inside and outside the health sector. To meet the challenge of engaging with the conditions underlying inequalities and promoting transformational change, equity-oriented research and practice in the field of indigenous health requires: engaging power, context-adapted strategies to improve service delivery, and mobilizing networks of collective action. The application of systems thinking approaches offers a pathway for the evolution of equity-oriented research and practice in collaborative, politically informed and mutually enhancing efforts to understand and transform the systems that generate and reproduce inequities in indigenous health. These approaches hold the potential to strengthen practice through the development of more nuanced, context-sensitive strategies for redressing power imbalances, reshaping the service delivery environment and fostering the dynamics of collective action for political reform.",21/02/2017,26/11/2018 12:49,14/04/2020 08:34,,26,,1,16,,Int J Equity Health,,,,,,,,eng,,,,,,,PMID: 28219429 PMCID: PMC5319053,,,,"Humans; Socioeconomic Factors; Delivery of Health Care/*standards; *Health systems; 1; Quality Improvement/*standards; *Accountability; *Equity; *Guatemala; *Indigenous health; *Indigenous people; *Systems thinking; Cultural Diversity; Health Services, Indigenous/*standards; Healthcare Disparities/*standards; Poverty; Universal Coverage/*standards; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, SRWSXAWD,journalArticle,2017,"Zafari, Zafar; Bryan, Stirling; Sin, Don D.; Conte, Tania; Khakban, Rahman; Sadatsafavi, Mohsen",A Systematic Review of Health Economics Simulation Models of Chronic Obstructive Pulmonary Disease.,Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research,,1524-4733 1098-3015,10.1016/j.jval.2016.08.003,,"BACKGROUND: Many decision-analytic models with varying structures have been developed to inform resource allocation in chronic obstructive pulmonary disease (COPD). OBJECTIVES: To review COPD models for their adherence to the best practice modeling recommendations and their assumptions regarding important aspects of the natural history of COPD. METHODS: A systematic search of English articles reporting on the development or application of a decision-analytic model in COPD was performed in MEDLINE, Embase, and citations within reviewed articles. Studies were summarized and evaluated on the basis of their adherence to the Consolidated Health Economic Evaluation Reporting Standards. They were also evaluated for the underlying assumptions about disease progression, heterogeneity, comorbidity, and treatment effects. RESULTS: Forty-nine models of COPD were included. Decision trees and Markov models were the most popular techniques (43 studies). Quality of reporting and adherence to the guidelines were generally high, especially in more recent publications. Disease progression was modeled through clinical staging in most studies. Although most studies (n = 43) had incorporated some aspects of COPD heterogeneity, only 8 reported the results across subgroups. Only 2 evaluations explicitly considered the impact of comorbidities. Treatment effect had been mostly modeled (20) as both reduction in exacerbation rate and improvement in lung function. CONCLUSIONS: Many COPD models have been developed, generally with similar structural elements. COPD is highly heterogeneous, and comorbid conditions play an important role in its burden. These important aspects, however, have not been adequately addressed in most of the published models.",2017-01,26/11/2018 12:49,14/04/2020 08:35,,152-162,,1,20,,Value Health,,,,,,,,eng,Copyright (c) 2017 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.,,,,,,PMID: 28212957,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; *Models, Economic; Markov Chains; Decision Support Techniques; Quality of Life; Practice Guidelines as Topic; Comorbidity; *cost-effectiveness; Disease Progression; *Markov models; 00; *chronic obstructive pulmonary disease; *discrete-event simulation; *modeling; Economics, Medical; Guideline Adherence; Pulmonary Disease, Chronic Obstructive/*economics/physiopathology; SLR; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, F3T9ICK2,journalArticle,2017,"Tuden, Danica S.; Borycki, Elizabeth M.; Kushniruk, Andre W.",Clinical Simulation: Evaluating the Usability of a Health Information System in a Telenurse Call Centre.,Studies in health technology and informatics,,0926-9630 0926-9630,,,"Telenursing is a specialized subset of nursing practice that has emerged in response to the development of health care technology. Telenurses use health information systems (HIS) as their main source of health information in order to assist callers with their health related concerns on the telephone. In order to ensure that the telenurse-caller encounter supports a safe, appropriate and patient focused outcome, it was important to evaluate the usability of (HIS) that telenurses use. The purpose of this paper is to describe usability issues that emerged during a clinical simulation study of nurses working in a call centre. Clinical simulation was thus chosen as the most comprehensive methodology in this study and its benefits will be discussed.",2017,26/11/2018 12:49,14/04/2020 08:35,,340-345,,,234,,Stud Health Technol Inform,,,,,,,,eng,,,,,,,PMID: 28186065,,,,Humans; *Health Information Systems; *Call Centers; *Telenursing; Clinical simulation; health information system (HIS); telenurse; Telephone; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TQAX4I7H,journalArticle,2017,"Vemer, Pepijn; Al, Maiwenn J.; Oppe, Mark; Rutten-van Molken, Maureen P. M. H.",Mix and match. A simulation study on the impact of mixed-treatment comparison methods on health-economic outcomes.,PloS one,,1932-6203 1932-6203,10.1371/journal.pone.0171292,,"BACKGROUND: Decision-analytic cost-effectiveness (CE) models combine many parameters, often obtained after meta-analysis. AIM: We compared different methods of mixed-treatment comparison (MTC) to combine transition and event probabilities derived from several trials, especially with respect to health-economic (HE) outcomes like (quality adjusted) life years and costs. METHODS: Trials were drawn from a simulated reference population, comparing two of four fictitious interventions. The goal was to estimate the CE between two of these. The amount of heterogeneity between trials was varied in scenarios. Parameter estimates were combined using direct comparison, MTC methods proposed by Song and Puhan, and Bayesian generalized linear fixed effects (GLMFE) and random effects models (GLMRE). Parameters were entered into a Markov model. Parameters and HE outcomes were compared with the reference population using coverage, statistical power, bias and mean absolute deviation (MAD) as performance indicators. Each analytical step was repeated 1,000 times. RESULTS: The direct comparison was outperformed by the MTC methods on all indicators, Song's method yielded low bias and MAD, but uncertainty was overestimated. Puhan's method had low bias and MAD and did not overestimate uncertainty. GLMFE generally had the lowest bias and MAD, regardless of the amount of heterogeneity, but uncertainty was overestimated. GLMRE showed large bias and MAD and overestimated uncertainty. Song's and Puhan's methods lead to the least amount of uncertainty, reflected in the shape of the CE acceptability curve. GLMFE showed slightly more uncertainty. CONCLUSIONS: Combining direct and indirect evidence is superior to using only direct evidence. Puhan's method and GLMFE are preferred.",2017,26/11/2018 12:49,14/04/2020 08:35,,e0171292,,2,12,,PLoS One,,,,,,,,eng,,,,,,,PMID: 28152099 PMCID: PMC5289594,,,,"Humans; Quality-Adjusted Life Years; Adult; Female; Male; Middle Aged; Young Adult; Aged; Health Care Costs/statistics & numerical data; Adolescent; Models, Theoretical; Bias; 00; *Economics, Medical; Chronic Disease/economics/therapy; Outcome and Process Assessment (Health Care)/*methods; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UKXV74J6,journalArticle,2017,"Bardach, Ariel Esteban; Garay, Osvaldo Ulises; Calderon, Maria; Pichon-Riviere, Andres; Augustovski, Federico; Marti, Sebastian Garcia; Cortinas, Paula; Gonzalez, Marino; Naranjo, Laura T.; Gomez, Jorge Alberto; Caporale, Joaquin Enzo",Health economic evaluation of Human Papillomavirus vaccines in women from Venezuela by a lifetime Markov cohort model.,BMC public health,,1471-2458 1471-2458,10.1186/s12889-017-4064-7,,"BACKGROUND: Cervical cancer (CC) and genital warts (GW) are a significant public health issue in Venezuela. Our objective was to assess the cost-effectiveness of the two available vaccines, bivalent and quadrivalent, against Human Papillomavirus (HPV) in Venezuelan girls in order to inform decision-makers. METHODS: A previously published Markov cohort model, informed by the best available evidence, was adapted to the Venezuelan context to evaluate the effects of vaccination on health and healthcare costs from the perspective of the healthcare payer in an 11-year-old girls cohort of 264,489. Costs and quality-adjusted life years (QALYs) were discounted at 5%. Eight scenarios were analyzed to depict the cost-effectiveness under alternative vaccine prices, exchange rates and dosing schemes. Deterministic and probabilistic sensitivity analyses were performed. RESULTS: Compared to screening only, the bivalent and quadrivalent vaccines were cost-saving in all scenarios, avoiding 2,310 and 2,143 deaths, 4,781 and 4,431 CCs up to 18,459 GW for the quadrivalent vaccine and gaining 4,486 and 4,395 discounted QALYs respectively. For both vaccines, the main determinants of variations in the incremental costs-effectiveness ratio after running deterministic and probabilistic sensitivity analyses were transition probabilities, vaccine and cancer-treatment costs and HPV 16 and 18 distribution in CC cases. When comparing vaccines, none of them was consistently more cost-effective than the other. In sensitivity analyses, for these comparisons, the main determinants were GW incidence, the level of cross-protection and, for some scenarios, vaccines costs. CONCLUSIONS: Immunization with the bivalent or quadrivalent HPV vaccines showed to be cost-saving or cost-effective in Venezuela, falling below the threshold of one Gross Domestic Product (GDP) per capita (104,404 VEF) per QALY gained. Deterministic and probabilistic sensitivity analyses confirmed the robustness of these results.",02/02/2017,26/11/2018 12:49,14/04/2020 08:34,,152,,1,17,,BMC Public Health,,,,,,,,eng,,,,,,,PMID: 28148228 PMCID: PMC5289055,,,,Humans; Quality-Adjusted Life Years; Adult; Female; Cohort Studies; Child; *Markov Chains; Health Care Costs/*statistics & numerical data; 00; *Cervical cancer; *Genital warts; *Health economic evaluation; *HPV vaccines; *Markov cohort model; *Venezuela; Condylomata Acuminata/economics/*prevention & control; Cost-Benefit Analysis/economics/*statistics & numerical data; Papillomavirus Infections/economics/*prevention & control; Papillomavirus Vaccines/administration & dosage/*economics; Uterine Cervical Neoplasms/economics/*prevention & control; Venezuela; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, T782C7T2,journalArticle,2017,"Hindhede, Anette Lykke; Aagaard-Hansen, Jens",Using Social Network Analysis as a Method to Assess and Strengthen Participation in Health Promotion Programs in Vulnerable Areas.,Health promotion practice,,1524-8399 1524-8399,10.1177/1524839916686029,,"This article provides an example of the application of social network analysis method to assess community participation thereby strengthening planning and implementation of health promotion programming. Community health promotion often takes the form of services that reach out to or are located within communities. The concept of community reflects the idea that people's behavior and well-being are influenced by interaction with others, and here, health promotion requires participation and local leadership to facilitate transmission and uptake of interventions for the overall community to achieve social change. However, considerable uncertainty exists over exact levels of participation in these interventions. The article draws on a mixed methods research within a community development project in a vulnerable neighborhood of a town in Denmark. It presents a detailed analysis of the way in which social network analysis can be used as a tool to display participation and nonparticipation in community development and health promotion activities, to help identify capacities and assets, mobilize resources, and finally to evaluate the achievements. The article concludes that identification of interpersonal ties among people who know one another well as well as more tenuous relationships in networks can be used by community development workers to foster greater cohesion and cooperation within an area.",2017-03,26/11/2018 12:49,14/04/2020 08:34,,175-183,,2,18,,Health Promot Pract,,,,,,,,eng,,,,,,,PMID: 28118745,,,,Humans; Socioeconomic Factors; Denmark; social network analysis; *health promotion; Residence Characteristics; 1; *Social Environment; *community intervention; *evaluation methods; *health disparities; *program planning and evaluation; *Vulnerable Populations; Emigrants and Immigrants; Health Promotion/*organization & administration/standards; Program Evaluation/*methods; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, SX2SMKQM,journalArticle,2017,"Chollette, Veronica; Beasley, Derrick D.; Abdiwahab, Ekland; Taplin, Stephen",Health Information Systems Approach to Managing Task Interdependence in Cancer Care Teams.,Journal of oncology practice,,1935-469X 1554-7477,10.1200/JOP.2016.020156,,,2017-03,26/11/2018 12:49,14/04/2020 08:34,,154-156,,3,13,,J Oncol Pract,,,,,,,,eng,,,,,,,PMID: 28118105,,,,Humans; Patient Care Team/*standards; 00; Neoplasms/*therapy; Health Information Systems/*standards; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2AMM9XX4,journalArticle,2017,"Wilson, Robert J.; Sulieman, Lina M.; VanHouten, Jacob P.; Halpern, Jennifer L.; Schwartz, Herbert S.; Devin, Clinton J.; Holt, Ginger E.",Cost-utility of osteoarticular allograft versus endoprosthetic reconstruction for primary bone sarcoma of the knee: A markov analysis.,Journal of surgical oncology,,1096-9098 0022-4790,10.1002/jso.24525,,"BACKGROUND: The most cost-effective reconstruction after resection of bone sarcoma is unknown. The goal of this study was to compare the cost effectiveness of osteoarticular allograft to endoprosthetic reconstruction of the proximal tibia or distal femur. METHODS: A Markov model was used. Revision and complication rates were taken from existing studies. Costs were based on Medicare reimbursement rates and implant prices. Health-state utilities were derived from the Health Utilities Index 3 survey with additional assumptions. Incremental cost-effectiveness ratios (ICER) were used with less than $100 000 per quality-adjusted life year (QALY) considered cost-effective. Sensitivity analyses were performed for comparison over a range of costs, utilities, complication rates, and revisions rates. RESULTS: Osteoarticular allografts, and a 30% price-discounted endoprosthesis were cost-effective with ICERs of $92.59 and $6 114.77. One-way sensitivity analysis revealed discounted endoprostheses were favored if allografts cost over $21 900 or endoprostheses cost less than $51 900. Allograft reconstruction was favored over discounted endoprosthetic reconstruction if the allograft complication rate was less than 1.3%. Allografts were more cost-effective than full-price endoprostheses. CONCLUSIONS: Osteoarticular allografts and price-discounted endoprosthetic reconstructions are cost-effective. Sensitivity analysis, using plausible complication and revision rates, favored the use of discounted endoprostheses over allografts. Allografts are more cost-effective than full-price endoprostheses.",2017-03,26/11/2018 12:49,14/04/2020 08:35,,257-265,,3,115,,J Surg Oncol,,,,,,,,eng,"(c) 2017 Wiley Periodicals, Inc.",,,,,,PMID: 28105636,,,,"Humans; Cost-Benefit Analysis; Markov Chains; *cost-effectiveness; Tibia/surgery; 00; *allograft; *endoprosthesis; *Ewing's; *femur; *osteosarcoma; *sarcoma; *tibia; *utility; Arthroplasty, Replacement, Knee/*economics/methods; Bone Neoplasms/economics/*surgery; Bone Transplantation/*economics/methods; Femur/surgery; Knee Joint/surgery; Osteosarcoma/economics/*surgery; Reconstructive Surgical Procedures/*economics/methods; Transplantation, Homologous; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CIVFI9NS,journalArticle,2017,"Lebcir, Reda; Demir, Eren; Ahmad, Raheelah; Vasilakis, Christos; Southern, David",A discrete event simulation model to evaluate the use of community services in the treatment of patients with Parkinson's disease in the United Kingdom.,BMC health services research,,1472-6963 1472-6963,10.1186/s12913-017-1994-9,,"BACKGROUND: The number of people affected by Parkinson's disease (PD) is increasing in the United Kingdom driven by population ageing. The treatment of the disease is complex, resource intensive and currently there is no known cure to PD. The National Health Service (NHS), the public organisation delivering healthcare in the UK, is under financial pressures. There is a need to find innovative ways to improve the operational and financial performance of treating PD patients. The use of community services is a new and promising way of providing treatment and care to PD patients at reduced cost than hospital care. The aim of this study is to evaluate the potential operational and financial benefits, which could be achieved through increased integration of community services in the delivery of treatment and care to PD patients in the UK without compromising care quality. METHODS: A Discrete Event Simulation model was developed to represent the PD care structure including patients' pathways, treatment modes, and the mix of resources required to treat PD patients. The model was parametrised with data from a large NHS Trust in the UK and validated using information from the same trust. Four possible scenarios involving increased use of community services were simulated on the model. RESULTS: Shifting more patients with PD from hospital treatment to community services will reduce the number of visits of PD patients to hospitals by about 25% and the number of PD doctors and nurses required to treat these patients by around 32%. Hospital based treatment costs overall should decrease by 26% leading to overall savings of 10% in the total cost of treating PD patients. CONCLUSIONS: The simulation model was useful in predicting the effects of increased use of community services on the performance of PD care delivery. Treatment policies need to reflect upon and formalise the use of community services and integrate these better in PD care. The advantages of community services need to be effectively shared with PD patients and carers to help inform management choices and care plans.",18/01/2017,26/11/2018 12:49,14/04/2020 08:34,,50,,1,17,,BMC Health Serv Res,,,,,,,,eng,,,,,,,PMID: 28100215 PMCID: PMC5241966,,,,"Humans; Quality of Health Care; Delivery of Health Care; Aged; Aged, 80 and over; *Models, Theoretical; United Kingdom; Costs and Cost Analysis; Interviews as Topic; 1; *Parkinson's disease; *Community services; *Discrete event simulation; *National health service; *United Kingdom; Community Health Services/*utilization; Nursing Staff; Parkinson Disease/economics/*therapy; 310",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 398I9EPP,journalArticle,2017,"Newhall, Karina; Albright, Benjamin; Tosteson, Anna; Ozanne, Elissa; Trus, Thadeus; Goodney, Philip P.",Cost-effectiveness of prophylactic appendectomy: a Markov model.,Surgical endoscopy,,1432-2218 0930-2794,10.1007/s00464-016-5391-y,,"BACKGROUND: Appendectomy is the most common emergency surgery performed in the USA. Removal of a non-inflamed appendix during unrelated abdominal surgery (prophylactic or incidental appendectomy) can prevent the downstream risks and costs of appendicitis. It is unknown whether such a strategy could be cost saving for the health system. METHODS: We considered hypothetical patient cohorts of varying ages from 18 to 80, undergoing elective laparoscopic abdominal and pelvic procedures. A Markov decision model using cost per life-year as the main outcome measure was constructed to simulate the trade-off between cost and risk of prophylactic appendectomy and the ongoing risk of developing appendicitis, with downstream costs and risks. Rates, probabilities, and costs of disease, treatment, and outcomes by patient age and gender were extracted from the literature. Sensitivity analyses were conducted using complications and costs of prophylactic appendectomy. RESULTS: With our base-case assumptions, including added cost of prophylactic appendectomy of $660, we find that prophylactic removal of the appendix is cost saving for males aged 18-27 and females aged",2017-09,26/11/2018 12:49,14/04/2020 08:35,,3596-3604,,9,31,,Surg Endosc,,,,,,,,eng,,,,,,,PMID: 28078461,,,,"Humans; United States; Adult; Female; Male; Middle Aged; Young Adult; *Cost-Benefit Analysis; Aged; Markov Chains; Adolescent; Aged, 80 and over; *Appendectomy; *Cost utility analysis; *Prophylactic surgical procedures; Appendectomy/*economics/methods; Appendicitis/economics/*prevention & control; Cost Savings/*statistics & numerical data; Models, Economic; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JK822PCC,journalArticle,2017,"Uhler, Lauren M.; Schultz, W. Randall; Hill, Austin D.; Koenig, Karl M.",Health Utility of Early Hemiarthroplasty vs Delayed Total Hip Arthroplasty for Displaced Femoral Neck Fracture in Elderly Patients: A Markov Model.,The Journal of arthroplasty,,1532-8406 0883-5403,10.1016/j.arth.2016.11.051,,"BACKGROUND: Treatment for femoral neck fracture among patients aged 65 years or older varies, with many surgeons preferring hemiarthroplasty (HA) over total hip arthroplasty (THA). There is evidence that THA may lead to better functional outcomes, although it also carries greater risk of mortality and dislocation rates. METHODS: We created a Markov decision model to examine the expected health utility for older patients with femoral neck fracture treated with early HA (performed within 48 hours) vs delayed THA (performed after 48 hours). Model inputs were derived from the literature. Health utilities were derived from previously fit patients aged more than 60 years. Sensitivity analyses on mortality and dislocation rates were conducted to examine the effect of uncertainty in the model parameters. RESULTS: In the base case, the average cumulative utility over 2 years was 0.895 for HA and 0.994 for THA. In sensitivity analyses, THA was preferred over HA until THA 30-day and 1-year mortality rates were increased to 1.3x the base case rates. THA was preferred over HA until the health utility for HA reached 98% that of THA. THA remained the preferred strategy when increasing the cumulative incidence of dislocation among THA patients from a base case of 4.4% up to 26.1%. CONCLUSION: We found that delayed THA provides greater health utility than early HA for older patients with femoral neck fracture, despite the increased 30-day and 1-year mortality associated with delayed surgery. Future studies should examine the cost-effectiveness of THA for femoral neck fracture.",2017-05,26/11/2018 12:49,14/04/2020 08:35,,1434-1438,,5,32,,J Arthroplasty,,,,,,,,eng,Copyright (c) 2016 Elsevier Inc. All rights reserved.,,,,,,PMID: 28065628,,,,"Humans; Cost-Benefit Analysis; Treatment Outcome; Female; Male; Middle Aged; Reproducibility of Results; Aged; Markov Chains; Aged, 80 and over; Incidence; Sensitivity and Specificity; Probability; 00; *Arthroplasty, Replacement, Hip/mortality; *decision analysis; *femoral neck fracture; *hemiarthroplasty; *Hemiarthroplasty/mortality; *hip fracture; *total hip arthroplasty; Femoral Neck Fractures/*surgery; Hip Dislocation/*etiology; Joint Dislocations/*surgery; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YFGUU5MA,journalArticle,2017,"Groen, Henk; Neelis, Esther G.; Poley, Marten J.; Olieman, Joanne F.; Scheenstra, Rene; Krabbe, Paul Fm; Dijkstra, Gerard; Rings, Edmond Hhm",Intestinal rehabilitation for children with intestinal failure is cost-effective: a simulation study.,The American journal of clinical nutrition,,1938-3207 0002-9165,10.3945/ajcn.116.135160,,"BACKGROUND: Children with intestinal failure (IF) depend on parenteral nutrition (PN). The goal in the treatment of IF is to wean children off PN through intestinal rehabilitation (IR). Although the healthcare burden of IF is enormous, to our knowledge there has been no previous cost-effectiveness analysis in pediatric IF including IR. OBJECTIVE: We sought to determine the cost-effectiveness of IR in terms of costs and life-years. DESIGN: We simulated the treatment of IF in children in a discrete-event model. Data for this model were derived from patient records, the Dutch Registry of Intestinal Failure and Transplantation, the Intestinal Transplant Registry, and the literature. The time horizon of the model was 40 y. Simulated patients were enrolled at a rate of 40 patients/mo for 10 y. Actual costs were calculated for hospital admissions, surgical interventions, endoscopies, PN, and immunosuppressive medication. We evaluated the cost-effectiveness of IR by comparing 1 scenario with IR with 1 scenario without IR. In the scenario with IR, a proportion of patients who represented those with the ability to wean off PN were assigned to IR. In the scenario without IR, all patients progressed to home PN (HPN). In both scenarios, a proportion of patients receiving HPN were eventually eligible for an intestinal transplantation. RESULTS: IR prolonged survival; the mean number of life-years per patient was 19.4 in the scenario with IR compared with 18.2 in the scenario without IR. Average total costs per patient were euro819,292 in the scenario with IR compared with euro1,176,830 in the scenario without IR (equivalent to 1,129,230 US$ and 1,622,025 US$, respectively, in January 2014); costs mainly included hospital admissions and PN. CONCLUSIONS: On the basis of our simulations, we concluded that IR improved the survival of children with IF and was associated with cost savings. Therefore, we consider IR to be a cost-effective treatment for children with IF.",2017-02,26/11/2018 12:49,14/04/2020 08:34,,417-425,,2,105,,Am J Clin Nutr,,,,,,,,eng,(c) 2017 American Society for Nutrition.,,,,,,PMID: 28052886,,,,"Humans; Cost-Benefit Analysis; Treatment Outcome; Health Care Costs; Child; *cost-effectiveness; Sensitivity and Specificity; Registries; 00; Hospitalization/economics; *(home) parenteral nutrition; *intestinal failure; *intestinal rehabilitation; *intestinal transplantation; Intestinal Diseases/economics/*rehabilitation; Intestines/*metabolism/physiopathology; Parenteral Nutrition, Home/economics; Parenteral Nutrition, Total/*economics; Review",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, SQIBIQT5,journalArticle,2017,"Pollom, Erqi L.; Lee, Kyueun; Durkee, Ben Y.; Grade, Madeline; Mokhtari, Daniel A.; Wahl, Daniel R.; Feng, Mary; Kothary, Nishita; Koong, Albert C.; Owens, Douglas K.; Goldhaber-Fiebert, Jeremy; Chang, Daniel T.",Cost-effectiveness of Stereotactic Body Radiation Therapy versus Radiofrequency Ablation for Hepatocellular Carcinoma: A Markov Modeling Study.,Radiology,,1527-1315 0033-8419,10.1148/radiol.2016161509,,"Purpose To assess the cost-effectiveness of stereotactic body radiation therapy (SBRT) versus radiofrequency ablation (RFA) for patients with inoperable localized hepatocellular carcinoma (HCC) who are eligible for both SBRT and RFA. Materials and Methods A decision-analytic Markov model was developed for patients with inoperable, localized HCC who were eligible for both RFA and SBRT to evaluate the cost-effectiveness of the following treatment strategies: (a) SBRT as initial treatment followed by SBRT for local progression (SBRT-SBRT), (b) RFA followed by RFA for local progression (RFA-RFA), (c) SBRT followed by RFA for local progression (SBRT-RFA), and (d) RFA followed by SBRT for local progression (RFA-SBRT). Probabilities of disease progression, treatment characteristics, and mortality were derived from published studies. Outcomes included health benefits expressed as discounted quality-adjusted life years (QALYs), costs in U.S. dollars, and cost-effectiveness expressed as an incremental cost-effectiveness ratio. Deterministic and probabilistic sensitivity analysis was performed to assess the robustness of the findings. Results In the base case, SBRT-SBRT yielded the most QALYs (1.565) and cost $197 557. RFA-SBRT yielded 1.558 QALYs and cost $193 288. SBRT-SBRT was not cost-effective, at $558 679 per QALY gained relative to RFA-SBRT. RFA-SBRT was the preferred strategy, because RFA-RFA and",2017-05,26/11/2018 12:49,14/04/2020 08:35,,460-468,,2,283,,Radiology,,,,,,,,eng,,,,,,,PMID: 28045603 PMCID: PMC5410949,,,,"Humans; Reproducibility of Results; Markov Chains; Prognosis; Health Care Costs/statistics & numerical data; United States/epidemiology; Computer Simulation; Risk Assessment/methods; Models, Economic; Carcinoma, Hepatocellular/*economics/*mortality; Catheter Ablation/*economics/mortality/utilization; Cost-Benefit Analysis/economics; Liver Neoplasms/*economics/*mortality; Postoperative Complications/economics/mortality; Prevalence; Proportional Hazards Models; Radiation Injuries/economics/mortality; Radiosurgery/*economics/mortality/utilization; Sensitivity and Specificity; Survival Rate; 00; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, A9J6WRFS,journalArticle,2017,"Kunst, Elicia L.; Mitchell, Marion; Johnston, Amy N. B.",Using simulation to improve the capability of undergraduate nursing students in mental health care.,Nurse education today,,1532-2793 0260-6917,10.1016/j.nedt.2016.12.012,,"INTRODUCTION: Mental health care is an increasing component of acute patient care and yet mental health care education can be limited in undergraduate nursing programs. The aim of this study was to establish if simulation learning can be an effective method of improving undergraduate nurses' capability in mental health care in an acute care environment. INTERVENTION: Undergraduate nursing students at an Australian university were exposed to several high-fidelity high-technology simulation activities that incorporated elements of acute emergency nursing practice and acute mental health intervention, scaffolded by theories of learning. This approach provided a safe environment for students to experience clinical practice, and develop their skills for dealing with complex clinical challenges. METHODS: Using a mixed method approach, the primary domains of interest in this study were student confidence, knowledge and ability. These were self-reported and assessed before and after the simulation activities (intervention) using a pre-validated survey, to gauge the self-rated capacity of students to initiate and complete effective care episodes. Focus group interviews were subsequently held with students who attended placement in the emergency department to explore the impact of the intervention on student performance in this clinical setting. RESULTS: Students who participated in the simulation activity identified and reported significantly increased confidence, knowledge and ability in mental health care post-intervention. They identified key features of the intervention included the impact of its realism on the quality of learning. There is some evidence to suggest that the intervention had an impact on the performance and reflection of students in the clinical setting. DISCUSSION: This study provides evidence to support the use of simulation to enhance student nurses' clinical capabilities in providing mental health care in acute care environments. Nursing curriculum development should be based on best-evidence to ensure that future nursing graduates have the skills and capability to provide high-quality, holistic care.",2017-03,26/11/2018 12:49,14/04/2020 08:34,,29-35,,,50,,Nurse Educ Today,,,,,,,,eng,Copyright (c) 2016 Elsevier Ltd. All rights reserved.,,,,,,PMID: 28011335,,,,"Humans; Learning; *Clinical Competence; Education, Nursing, Baccalaureate; Australia; Nurses; High Fidelity Simulation Training/*methods; Health Knowledge, Attitudes, Practice; Students; *Students, Nursing; Simulation; Nursing; 00; Mental health; *Psychiatric Nursing; Psychiatric nursing; Mannequin; Nurse education; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, SHL4ZS52,journalArticle,2017,"Montgomery, Stephen M.; Maruszczak, Maciej J.; Slater, David; Kusel, Jeanette; Nicholas, Richard; Adlard, Nicholas",A discrete event simulation to model the cost-utility of fingolimod and natalizumab in rapidly evolving severe relapsing-remitting multiple sclerosis in the UK.,Journal of medical economics,,1941-837X 1369-6998,10.1080/13696998.2016.1276070,,"OBJECTIVE: Two disease-modifying therapies are licensed in the EU for use in rapidly-evolving severe (RES) relapsing-remitting multiple sclerosis (RRMS), fingolimod and natalizumab. Here a discrete event simulation (DES) model to analyze the cost-effectiveness of natalizumab and fingolimod in the RES population, from the perspective of the National Health Service (NHS) in the UK, is reported. METHODS: A DES model was developed to track individual RES patients, based on Expanded Disability Status Scale scores. Individual patient characteristics were taken from the RES sub-groups of the pivotal trials for fingolimod. Utility data were in line with previous models. Published costs were inflated to NHS cost year 2015. Owing to the confidential patient access scheme (PAS) discount applied to fingolimod in the UK, a range of discount levels were applied to the fingolimod list price, to capture the likelihood of natalizumab being cost-effective in a real-world setting. RESULTS: At the lower National Institute of Health and Care Excellence (NICE) threshold of pound20,000/quality-adjusted life year (QALY), fingolimod only required a discount greater than 0.8% of list price to be cost-effective. At the upper threshold of pound30,000/QALY employed by the NICE, fingolimod was cost-effective if the confidential discount is greater than 2.5%. Sensitivity analyses conducted using fingolimod list-price showed the model to be most sensitive to changes in the cost of each drug, particularly fingolimod. CONCLUSIONS: The DES model shows that only a modest discount to the UK fingolimod list-price is required to make fingolimod a more cost-effective option than natalizumab in RES RRMS.",2017-05,26/11/2018 12:49,14/04/2020 08:35,,474-482,,5,20,,J Med Econ,,,,,,,,eng,,,,,,,PMID: 28008769,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Markov Chains; Computer Simulation; cost-effectiveness; United Kingdom; Models, Econometric; State Medicine; 1; Disability Evaluation; Fees, Pharmaceutical; fingolimod; Fingolimod Hydrochloride/*economics/therapeutic use; Immunosuppressive Agents/*economics/therapeutic use; Multiple sclerosis; Multiple Sclerosis, Relapsing-Remitting/*drug therapy/economics; natalizumab; Natalizumab/*economics/therapeutic use; rapidly evolving severe relapsing-remitting multiple sclerosis; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KE4XMUIE,journalArticle,2016,"Calohan, Jess; Pauli, Eric; Combs, Teresa; Creel, Andrea; Convoy, Sean; Owen, Regina",Using Simulation in a Psychiatric Mental Health Nurse Practitioner Doctoral Program.,Journal of professional nursing : official journal of the American Association of Colleges of Nursing,,1532-8481 8755-7223,10.1016/j.profnurs.2016.03.009,,"The use and effectiveness of simulation with standardized patients in undergraduate and graduate nursing education programs is well documented. Simulation has been primarily used to develop health assessment skills. Evidence supports using simulation and standardized patients in psychiatric-mental health nurse practitioner (PMHNP) programs is useful in developing psychosocial assessment skills. These interactions provide individualized and instantaneous clinical feedback to the student from faculty, peers, and standardized patients. Incorporating simulation into advanced practice psychiatric-mental health nursing curriculum allows students to develop the necessary requisite skills and principles needed to safely and effectively provide care to patients. There are no documented standardized processes for using simulation throughout a doctor of nursing practice PMHNP curriculum. The purpose of this article is to describe a framework for using simulation with standardized patients in a PMHNP curriculum. Students report high levels of satisfaction with the simulation experience and believe that they are more prepared for clinical rotations. Faculty feedback indicates that simulated clinical scenarios are a method to ensure that each student experiences demonstrate a minimum standard of competency ahead of clinical rotations with live patients. Initial preceptor feedback indicates that students are more prepared for clinical practice and function more independently than students that did not experience this standardized clinical simulation framework.",2016-12,26/11/2018 12:49,14/04/2020 08:34,,458-462,,6,32,,J Prof Nurs,,,,,,,,eng,Published by Elsevier Inc.,,,,,,PMID: 27964816,,,,"Humans; Clinical Competence; *Patient Simulation; Curriculum; Psychiatric Nursing/*education; Nurse Practitioners/*education; Simulation; 00; Education, Nursing, Graduate/*methods; Graduate education; Nurse practitioner curriculum; Psychiatric-Mental health nurse practitioner; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RPNPNICJ,journalArticle,2017,"Valles, Xavier; Lusala, Patrick Lunzayiladio; Devaliere, Hortense; Metsia-Thiam, Marie-Michele; Aguilar, Daniel; Cheyron, Anne-Laure; Cannet, Didier",Network analysis of knowledge and practices regarding sexual and reproductive health: a study among adolescent street girls in Kinshasa (DRC).,The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception,,1473-0782 1362-5187,10.1080/13625187.2016.1262023,,"OBJECTIVES: The aim of the study was to ascertain the influence of knowledge and interventions in sexual and reproductive health and contraception practices among adolescent street girls from Kinshasa, Democratic Republic of the Congo. METHODS: A cross-sectional study was carried out among street girls between 12 and 21 years of age. A standardised questionnaire was used, encompassing socio-demographic data and knowledge and practices regarding sexual and reproductive health. A network analysis was carried out. RESULTS: The study comprised 293 street girls. The mean age was 17.1 years (range 12-21 years) and the mean time spent living on the streets was 3.9 years (range 0-15 years). Commercial sex was reported by 78.5% (95% confidence interval [CI] 73.3%, 83.2%) as the main source of their income. During their last sexual intercourse, 44.0% (95%CI 38.1%, 50.4%) had not used a condom; 29.3% (95%CI 23.3%, 35.9%) had used hormonal contraception. Previous pregnancy was reported by 62.5% (95%CI 56.7%, 68.3%) and current pregnancy by 12.3% (95%CI 8.8%, 17.2%); 24.5% of previous pregnancies ended in voluntary termination, with a higher rate among the youngest street girls (12-15 years, 50.0%; p = 0.01). Time spent living on the streets was independently associated with pregnancy (odds ratio 1.2; 95%CI 1.1, 1.4). Practices and outcomes (previous or current pregnancy) were poorly correlated with knowledge about sexual and reproductive health. The network analysis confirmed the poor influence of exposure to intervention activities on sexual and reproductive health practices and outcomes, but did confirm a centrality effect of knowledge about HIV/AIDS. CONCLUSION: Street girls in Kinshasa are extremely vulnerable with regard to their sexual and reproductive health, especially the youngest street girls. Behavioural and biomedical interventions have had limited influence. Structural and societal changes are necessary to positively impact street girls' sexual and reproductive health. Knowledge about HIV/AIDS than about risk of pregnancy had a greater influence on sexual and reproductive health practices.",2017-02,26/11/2018 12:49,14/04/2020 08:35,,62-69,,1,22,,Eur J Contracept Reprod Health Care,,,,,,,,eng,,,,,,,PMID: 27957867,,,,"Humans; Surveys and Questionnaires; Female; Young Adult; Child; Adolescent; Pregnancy; Time Factors; Cross-Sectional Studies; *Health Knowledge, Attitudes, Practice; Age Factors; HIV/AIDS; 00; network analysis; Sexual Behavior/*psychology; Adolescent Behavior/*psychology; Contraception; Contraception Behavior/*psychology/statistics & numerical data; Contraception/methods/psychology/statistics & numerical data; Democratic Republic of the Congo; Homeless Youth/psychology/statistics & numerical data; Kinshasa (DRC); Pregnancy in Adolescence/psychology/statistics & numerical data; Sex Work/*psychology/statistics & numerical data; sexual and reproductive health; street girls; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, AN4TEAB5,journalArticle,2017,"Kron, Frederick W.; Fetters, Michael D.; Scerbo, Mark W.; White, Casey B.; Lypson, Monica L.; Padilla, Miguel A.; Gliva-McConvey, Gayle A.; Belfore, Lee A. 2nd; West, Temple; Wallace, Amelia M.; Guetterman, Timothy C.; Schleicher, Lauren S.; Kennedy, Rebecca A.; Mangrulkar, Rajesh S.; Cleary, James F.; Marsella, Stacy C.; Becker, Daniel M.",Using a computer simulation for teaching communication skills: A blinded multisite mixed methods randomized controlled trial.,Patient education and counseling,,1873-5134 0738-3991,10.1016/j.pec.2016.10.024,,"OBJECTIVES: To assess advanced communication skills among second-year medical students exposed either to a computer simulation (MPathic-VR) featuring virtual humans, or to a multimedia computer-based learning module, and to understand each group's experiences and learning preferences. METHODS: A single-blinded, mixed methods, randomized, multisite trial compared MPathic-VR (N=210) to computer-based learning (N=211). Primary outcomes: communication scores during repeat interactions with MPathic-VR's intercultural and interprofessional communication scenarios and scores on a subsequent advanced communication skills objective structured clinical examination (OSCE). Multivariate analysis of variance was used to compare outcomes. SECONDARY OUTCOMES: student attitude surveys and qualitative assessments of their experiences with MPathic-VR or computer-based learning. RESULTS: MPathic-VR-trained students improved their intercultural and interprofessional communication performance between their first and second interactions with each scenario. They also achieved significantly higher composite scores on the OSCE than computer-based learning-trained students. Attitudes and experiences were more positive among students trained with MPathic-VR, who valued its providing immediate feedback, teaching nonverbal communication skills, and preparing them for emotion-charged patient encounters. CONCLUSIONS: MPathic-VR was effective in training advanced communication skills and in enabling knowledge transfer into a more realistic clinical situation. PRACTICE IMPLICATIONS: MPathic-VR's virtual human simulation offers an effective and engaging means of advanced communication training.",2017-04,26/11/2018 12:49,14/04/2020 08:34,,748-759,,4,100,,Patient Educ Couns,,,,,,,,eng,Copyright (c) 2016 Elsevier Ireland Ltd. All rights reserved.,,,,,,PMID: 27939846 PMCID: PMC5385273,,,,"Humans; Physician-Patient Relations; Adult; Female; Male; *Patient Simulation; Curriculum; *Computer Simulation; *Clinical Competence; *Simulation; Single-Blind Method; *Communication; User-Computer Interface; 00; Students, Medical/*psychology; *Breaking bad news; *Communication training; *Computer simulation; *Computer-based conversational agent; *Cultural competence; *Doctor-patient relationship; *Healthcare communication; *Human-computer interaction; *Intelligent tutoring systems; *Inter-professional communication; *Intercultural communication; *Knowledge transfer; *Mindful practice; *Mixed methods research; *Nonverbal communication; *Reflection in action; *Reflection on action; *Training transfer; *Virtual Human; Education, Medical; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IQCKAEFD,journalArticle,2016,"Delgleize, Emmanuelle; Leeuwenkamp, Oscar; Theodorou, Eleni; Van de Velde, Nicolas",Cost-effectiveness analysis of routine pneumococcal vaccination in the UK: a comparison of the PHiD-CV vaccine and the PCV-13 vaccine using a Markov model.,BMJ open,,2044-6055 2044-6055,10.1136/bmjopen-2015-010776,,"OBJECTIVES: In 2010, the 13-valent pneumococcal conjugate vaccine (PCV-13) replaced the 7-valent vaccine (introduced in 2006) for vaccination against invasive pneumococcal diseases (IPDs), pneumonia and acute otitis media (AOM) in the UK. Using recent evidence on the impact of PCVs and epidemiological changes in the UK, we performed a cost-effectiveness analysis (CEA) to compare the pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) with PCV-13 in the ongoing national vaccination programme. DESIGN: CEA was based on a published Markov model. The base-case scenario accounted only for direct medical costs. Work days lost were considered in alternative scenarios. SETTING: Calculations were based on serotype and disease-specific vaccine efficacies, serotype distributions and UK incidence rates and medical costs. POPULATION: Health benefits and costs related to IPD, pneumonia and AOM were accumulated over the lifetime of a UK birth cohort. INTERVENTIONS: Vaccination of infants at 2, 4 and 12 months with PHiD-CV or PCV-13, assuming complete coverage and adherence. OUTCOME MEASURES: The incremental cost-effectiveness ratio (ICER) was computed by dividing the difference in costs between the programmes by the difference in quality-adjusted life-years (QALY). RESULTS: Under our model assumptions, both vaccines had a similar impact on IPD and pneumonia, but PHiD-CV generated a greater reduction in AOM cases (161 918), AOM-related general practitioner consultations (31 070) and tympanostomy tube placements (2399). At price parity, PHiD-CV vaccination was dominant over PCV-13, saving 734 QALYs as well as pound3.68 million to the National Health Service (NHS). At the lower list price of PHiD-CV, the cost-savings would increase to pound45.77 million. CONCLUSIONS: This model projected that PHiD-CV would provide both incremental health benefits and cost-savings compared with PCV-13 at price parity. Using PHiD-CV could result in substantial budget savings to the NHS. These savings could be used to implement other life-saving interventions.",30/11/2016,26/11/2018 12:49,14/04/2020 08:34,,e010776,,11,6,,BMJ Open,,,,,,,,eng,Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.,,,,,,PMID: 27903558 PMCID: PMC5168567,,,,"Humans; Program Evaluation; Cost-Benefit Analysis; Markov Chains; Models, Statistical; Infant; United Kingdom; *HEALTH ECONOMICS; *Immunization Programs; *IMMUNOLOGY; Otitis Media/epidemiology/immunology/*prevention & control; Pneumococcal Infections/epidemiology/immunology/*prevention & control; Pneumococcal Vaccines/*therapeutic use; State Medicine; Vaccination/*methods; Vaccines, Conjugate/*therapeutic use; 00; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IT4KXBJL,journalArticle,2017,"Pitt, Michael B.; Eppich, Walter J.; Shane, Margaret L.; Butteris, Sabrina M.",Using Simulation in Global Health: Considerations for Design and Implementation.,Simulation in healthcare : journal of the Society for Simulation in Healthcare,,1559-713X 1559-2332,10.1097/SIH.0000000000000209,,"STATEMENT: Providers and educators increasingly participate in global health work during their careers. Simulation can play an important role in both preparing learners for work in resource-limited settings and training providers in these countries. However, little guidance exists for educators interested in creating and implementing scenarios for these settings. We discuss several key considerations unique to global health simulation ranging from addressing common cultural differences surrounding healthcare and varied regional approaches to disease identification and management to understanding precisely what resources exist in the setting and what strategies can be used to provide care when the expected resources are not available. We also discuss specific strategies for considering sustainability and for facilitating scenarios in these settings. We developed our recommendations on the basis of existing literature and our own work designing and implementing simulation curricula in resource-limited countries and preparing providers for work in these settings.",2017-06,26/11/2018 12:49,14/04/2020 08:35,,177-181,,3,12,,Simul Healthc,,,,,,,,eng,,,,,,,PMID: 27902533,,,,"Humans; *Global Health; Pharmaceutical Preparations/supply & distribution; Cooperative Behavior; Terminology as Topic; *Developing Countries; 00; Simulation Training/*organization & administration; *Cultural Competency; Equipment and Supplies, Hospital/supply & distribution; Health Care Rationing/methods; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, R5I6KHFH,journalArticle,2016,"Toumi, Mondher; Beck, Ekkehard; Sherman, Steve; Mohseninejad, Leyla; Aballea, Samuel",About the advantages and disadvantages of discrete-event simulation for health economic analyses.,Expert review of pharmacoeconomics & outcomes research,,1744-8379 1473-7167,10.1080/14737167.2016.1259572,,,2016-12,26/11/2018 12:49,14/04/2020 08:35,,651-652,,6,16,,Expert Rev Pharmacoecon Outcomes Res,,,,,,,,eng,,,,,,,PMID: 27885884,,,,"Humans; *Models, Economic; *Markov Chains; Computer Simulation; 1; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8PGJNAI3,journalArticle,2016,"Dionisio, Kathie L.; Chang, Howard H.; Baxter, Lisa K.",A simulation study to quantify the impacts of exposure measurement error on air pollution health risk estimates in copollutant time-series models.,Environmental health : a global access science source,,1476-069X 1476-069X,10.1186/s12940-016-0186-0,,BACKGROUND: Exposure measurement error in copollutant epidemiologic models has the potential to introduce bias in relative risk (RR) estimates. A simulation study was conducted using empirical data to quantify the impact of correlated measurement errors in time-series analyses of air pollution and health. METHODS:,25/11/2016,26/11/2018 12:49,14/04/2020 08:34,,114,,1,15,,Environ Health,,,,,,,,eng,,,,,,,PMID: 27884187 PMCID: PMC5123332,,,,"Humans; Computer Simulation; *Models, Theoretical; Risk; Bias; Air Pollutants/*analysis; *Bias; 00; *Copollutant; *Exposure assessment; *Exposure measurement error; *Exposure modeling; Air Pollution/*analysis; Carbon Monoxide/analysis; Cities/epidemiology; Emergency Service, Hospital/statistics & numerical data; Environmental Exposure/analysis; Georgia/epidemiology; Nitrogen Oxides/analysis; Ozone/analysis; Particulate Matter/analysis; Respiratory Tract Diseases/*epidemiology; Sulfates/analysis; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GL6E94AR,journalArticle,2017,"Egenberg, Signe; Oian, Pal; Eggebo, Torbjorn Moe; Arsenovic, Mirjana Grujic; Bru, Lars Edvin","Changes in self-efficacy, collective efficacy and patient outcome following interprofessional simulation training on postpartum haemorrhage.",Journal of clinical nursing,,1365-2702 0962-1067,10.1111/jocn.13666,,"AIMS AND OBJECTIVES: To examine whether interprofessional simulation training on management of postpartum haemorrhage enhances self-efficacy and collective efficacy and reduces the blood transfusion rate after birth. BACKGROUND: Postpartum haemorrhage is a leading cause of maternal morbidity and mortality worldwide, although it is preventable in most cases. Interprofessional simulation training might help improve the competence of health professionals dealing with postpartum haemorrhage, and more information is needed to determine its potential. DESIGN: Multimethod, quasi-experimental, pre-post intervention design. METHODS: Interprofessional simulation training on postpartum haemorrhage was implemented for midwives, obstetricians and auxiliary nurses in a university hospital. Training included realistic scenarios and debriefing, and a measurement scale for perceived postpartum haemorrhage-specific self-efficacy, and collective efficacy was developed and implemented. Red blood cell transfusion was used as the dependent variable for improved patient outcome pre-post intervention. RESULTS: Self-efficacy and collective efficacy levels were significantly increased after training. The overall red blood cell transfusion rate did not change, but there was a significant reduction in the use of >/=5 units of blood products related to severe bleeding after birth. CONCLUSION: The study contributes to new knowledge on how simulation training through mastery and vicarious experiences, verbal persuasion and psychophysiological state might enhance postpartum haemorrhage-specific self-efficacy and collective efficacy levels and thereby predict team performance. The significant reduction in severe postpartum haemorrhage after training, indicated by reduction in >/=5 units of blood transfusions, corresponds well with the improvement in collective efficacy, and might reflect the emphasis on collective efforts to counteract severe cases of postpartum haemorrhage. RELEVANCE TO CLINICAL PRACTICE: Interprofessional simulation training in teams may contribute to enhanced prevention and management of postpartum haemorrhage, shown by a significant increase in perceived efficacy levels combined with an indicated reduction of severe postpartum haemorrhage after training.",2017-10,26/11/2018 12:49,14/04/2020 08:34,,3174-3187,,19-20,26,,J Clin Nurs,,,,,,,,eng,(c) 2016 John Wiley & Sons Ltd.,,,,,,PMID: 27874995,,,,Humans; Surveys and Questionnaires; *Simulation Training; Female; Interprofessional Relations; Pregnancy; *Self Efficacy; patient safety; *Attitude of Health Personnel; teamwork; 00; simulation training; Obstetrics/education; midwifery; Midwifery/education; Non-Randomized Controlled Trials as Topic; Nurses' Aides/education; postpartum haemorrhage; Postpartum Hemorrhage/*prevention & control; self-efficacy; transfusion; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IU2ZUEZG,journalArticle,2016,"Camacho, Elizabeth M.; Ntais, Dionysios; Coventry, Peter; Bower, Peter; Lovell, Karina; Chew-Graham, Carolyn; Baguley, Clare; Gask, Linda; Dickens, Chris; Davies, Linda M.",Long-term cost-effectiveness of collaborative care (vs usual care) for people with depression and comorbid diabetes or cardiovascular disease: a Markov model informed by the COINCIDE randomised controlled trial.,BMJ open,,2044-6055 2044-6055,10.1136/bmjopen-2016-012514,,"OBJECTIVES: To evaluate the long-term cost-effectiveness of collaborative care (vs usual care) for treating depression in patients with diabetes and/or coronary heart disease (CHD). SETTING: 36 primary care general practices in North West England. PARTICIPANTS: 387 participants completed baseline assessment (collaborative care: 191; usual care: 196) and full or partial 4-month follow-up data were captured for 350 (collaborative care: 170; usual care: 180). 62% of participants were male, 14% were non-white. Participants were aged >/=18 years, listed on a Quality and Outcomes Framework register for CHD and/or type 1 or 2 diabetes mellitus, with persistent depressive symptoms. Patients with psychosis or type I/II bipolar disorder, actively suicidal, in receipt of services for substance misuse, or already in receipt of psychological therapy for depression were excluded. INTERVENTION: Collaborative care consisted of evidence-based low-intensity psychological treatments, delivered over 3 months and case management by a practice nurse and a Psychological Well Being Practitioner. OUTCOME MEASURES: As planned, the primary measure of cost-effectiveness was the incremental cost-effectiveness ratio (cost per quality-adjusted life year (QALY)). A Markov model was constructed to extrapolate the trial results from short-term to long-term (24 months). RESULTS: The mean cost per participant of collaborative care was pound317 (95% CI 284 to 350). Over 24 months, it was estimated that collaborative care was associated with greater healthcare usage costs (net cost pound674 (95% CI -30 953 to 38 853)) and QALYs (net QALY gain 0.04 (95% CI -0.46 to 0.54)) than usual care, resulting in a cost per QALY gained of pound16 123, and a likelihood of being cost-effective of 0.54 (willingness to pay threshold of pound20 000). CONCLUSIONS: Collaborative care is a potentially cost-effective long-term treatment for depression in patients with comorbid physical and mental illness. The estimated cost per QALY gained was below the threshold recommended by English decision-makers. Further, long-term primary research is needed to address uncertainty associated with estimates of cost-effectiveness. TRIAL REGISTRATION NUMBER: ISRCTN80309252; Post-results.",07/10/2016,26/11/2018 12:49,14/04/2020 08:34,,e012514,,10,6,,BMJ Open,,,,,,,,eng,Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.,,,,,,PMID: 27855101 PMCID: PMC5073527,,,,"Humans; Primary Health Care; Quality-Adjusted Life Years; Treatment Outcome; Health Care Costs; Adult; Middle Aged; Young Adult; *Cost-Benefit Analysis; Aged; Markov Chains; Quality of Life; Adolescent; Aged, 80 and over; Comorbidity; *HEALTH ECONOMICS; *Cooperative Behavior; *MENTAL HEALTH; *Patient Care Team; *PRIMARY CARE; Cardiovascular Diseases/complications/economics/*therapy; Depression/complications/economics/*therapy; Depressive Disorder/complications/economics/*therapy; Diabetes Mellitus/economics/*therapy; England; General Practice; Standard of Care; 1; Markov; 320",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, K5ZAAKMC,journalArticle,2016,"Caro, J. Jaime; Moller, Jorgen",Reply: Letter to the Editor: About the advantages and disadvantages of discrete-event simulation for health economic analyses.,Expert review of pharmacoeconomics & outcomes research,,1744-8379 1473-7167,10.1080/14737167.2016.1259573,,,2016-12,26/11/2018 12:49,14/04/2020 08:34,,653,,6,16,,Expert Rev Pharmacoecon Outcomes Res,,,,,,,,eng,,,,,,,PMID: 27831819,,,,"Humans; *Models, Economic; *Markov Chains; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, H5WK7IFQ,journalArticle,2017,"DeLay, Dawn; Hanish, Laura D.; Zhang, Linlin; Martin, Carol Lynn",Assessing the Impact of Homophobic Name Calling on Early Adolescent Mental Health: A Longitudinal Social Network Analysis of Competing Peer Influence Effects.,Journal of youth and adolescence,,1573-6601 0047-2891,10.1007/s10964-016-0598-8,,"The goal of the current study was to improve our understanding of why adolescence is a critical period for the consideration of declining mental health. We did this by focusing on the impact of homophobic name calling on early adolescent mental health after the transition to middle school. Because we know that homophobic name calling emerges within a dynamic peer group structure, we used longitudinal social network analysis to assess the relation between homophobic name calling, depressive symptoms, and self-esteem while simultaneously limiting bias from alternative peer socialization mechanisms. A sample of adolescents who recently transitioned to a large public middle school (N = 299; 53 % girls; M age = 11.13 years, SD = 0.48) were assessed. Longitudinal assessments of peer relationship networks, depressive symptoms, and self-esteem were collected during the fall and spring of the academic year. The results suggest that, after accounting for the simultaneous effect of alternative peer socialization processes, adolescent experiences of homophobic name calling in the fall predict higher levels of depressive symptoms and lower levels of self-esteem over the course of the academic year. These findings provide evidence of a significant influence of homophobic name calling on adolescent mental health.",2017-05,26/11/2018 12:49,14/04/2020 08:34,,955-969,,5,46,,J Youth Adolesc,,,,,,,,eng,,,,,,,PMID: 27826744,,,,Humans; Female; Male; Adolescent; Interpersonal Relations; Longitudinal Studies; *Self Concept; Social Support; Adolescent Health; Schools; 00; *Mental Health; *Social networks; Adolescent Behavior/*psychology; *Adolescence; *Homophobic name calling; *Mental health; *Peer Influence; *Peer relationships; *Socialization; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TXFS3QYN,journalArticle,2017,"Claxton, Lindsay; Hodgson, Robert; Taylor, Matthew; Malcolm, Bill; Pulikottil Jacob, Ruth",Simulation Modelling in Ophthalmology: Application to Cost Effectiveness of Ranibizumab and Aflibercept for the Treatment of Wet Age-Related Macular Degeneration in the United Kingdom.,PharmacoEconomics,,1179-2027 1170-7690,10.1007/s40273-016-0459-z,,"BACKGROUND: Previously developed models in ophthalmology have generally used a Markovian structure. There are a number of limitations with this approach, most notably the ability to base patient outcomes on best-corrected visual acuity (BCVA) in both eyes, which may be overcome using a different modelling structure. Simulation modelling allows for this to be modelled more precisely, and therefore may provide more accurate and relevant estimates of the cost effectiveness of ophthalmology interventions. OBJECTIVE: This study aimed to explore the appropriateness of simulation modelling in ophthalmology, using the disease area of wet age-related macular degeneration (wAMD) as an example. METHODS: A de novo economic model was built using a patient-level simulation, which compared ranibizumab with aflibercept in wAMD. Disease progression was measured using BCVA. Health-related quality of life (HRQoL) was estimated using a regression analysis linking BCVA in each eye to utility. The analysis was from the perspective of the National Health Service in the UK. Five different regression models were explored and were based on BCVA in either one eye or both eyes. RESULTS: The model outputs provide some evidence to support the hypothesis that the analyses using the two-eye models for estimating HRQoL generate a more accurate estimation of incremental quality-adjusted life-years (QALYs) associated with the positive treatment effect for ranibizumab versus aflibercept. Second-order analysis broadly supported these findings, and showed that the variation in incremental costs was slightly lower than in incremental QALYs. The second-order analysis estimated similar incremental costs and a greater overall variation in incremental QALYs than the first-order analysis, suggesting important non-linearities within the model. CONCLUSIONS: This analysis suggests that patient-level simulation models may be well suited to representing the real-world patient pathway in wAMD, particularly when aspects of disease progression cannot be adequately captured using a Markov structure. The benefits of a simulation approach can be demonstrated in the modelling of HRQoL as a function of BCVA in both eyes.",2017-02,26/11/2018 12:49,14/04/2020 08:34,,237-248,,2,35,,Pharmacoeconomics,,,,,,,,eng,,,,,,,PMID: 27787744,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; *Models, Economic; Markov Chains; Quality of Life; Computer Simulation; United Kingdom; Angiogenesis Inhibitors/*administration & dosage/economics; Disease Progression; Ranibizumab/*administration & dosage/economics; Receptors, Vascular Endothelial Growth Factor/*administration & dosage; Recombinant Fusion Proteins/*administration & dosage/economics; Regression Analysis; Visual Acuity; Wet Macular Degeneration/*drug therapy/economics/physiopathology; 00; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, F6LHUEE9,journalArticle,2016,"Versteegh, Matthijs",Impact on the Incremental Cost-Effectiveness Ratio of Using Alternatives to EQ-5D in a Markov Model for Multiple Sclerosis.,PharmacoEconomics,,1179-2027 1170-7690,10.1007/s40273-016-0421-0,,"OBJECTIVES: This study responds to a request in the National Institute for Health and Care Excellence (NICE) guidance to assess the impact of using alternative sources of utility values, applied to multiple sclerosis (MS). METHODS: Incremental cost-effectiveness ratios (ICERs) were calculated using utility values based on UK and Dutch values of EQ-5D, two UK mappings and one Dutch mapping of EQ-5D and two condition-specific instruments: the UK eight-dimensional Multiple Sclerosis Impact Scale (MSIS-8D) and the Dutch Multiple Sclerosis Impact Scale Preference-Based Measure (MSIS-PBM). Deterministic and Monte-Carlo simulation-based ICERs were estimated for glatiramer acetate versus symptom management using a lifetime Markov model. RESULTS: For both UK and Dutch perspectives, mapped and condition-specific utility values expressed significantly higher quality of life for the worst health state of the model than did EQ-5D. The ICER of glatiramer acetate with EQ-5D was US$182,291 for The Netherlands and US$153,476 for the UK. Ratios for mapped and condition-specific utilities were between 20 and 60 % higher. CONCLUSION: The overestimation of quality of life of patients with MS by mapped EQ-5D or condition-specific utility values, relative to observed EQ-5D, increases the ICER substantially in a lifetime Markov model.",2016-11,26/11/2018 12:49,14/04/2020 08:35,,1133-1144,,11,34,,Pharmacoeconomics,,,,,,,,eng,,,,,,,PMID: 27282692 PMCID: PMC5073108,,,,"Humans; Netherlands; Surveys and Questionnaires; Cost-Benefit Analysis; Quality-Adjusted Life Years; Markov Chains; Severity of Illness Index; United Kingdom; *Quality of Life; Adjuvants, Immunologic/economics/*therapeutic use; Glatiramer Acetate/economics/*therapeutic use; Health Status; Multiple Sclerosis/*economics/physiopathology/therapy; 00; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Q37UUHNY,journalArticle,2016,"Vottonen, Pasi; Kankaanpaa, Eila",Cost-effectiveness of treating wet age-related macular degeneration at the Kuopio University Hospital in Finland based on a two-eye Markov transition model.,Acta ophthalmologica,,1755-3768 1755-375X,10.1111/aos.13185,,"PURPOSE: Wet age-related macular degeneration (AMD) is the leading cause of blindness worldwide, which can be treated with regular intraocular anti-vascular endothelial growth factor (VEGF) injections. In this study, we wanted to evaluate whether less frequent injections of aflibercept would make it more cost-effective when compared with ranibizumab and low priced bevacizumab. METHODS: We used a two-eye model to simulate the progression and the treatment of the disease. We selected an 8-year period, 3-month cycles and five health states based on the visual acuity of the better-seeing eye. The transition probabilities and utilities attached to the health states were gathered from previous studies. We conducted the analysis from the hospital perspective and we used the health care costs obtained from Kuopio University Hospital. The costs of intraocular adverse events were taken into account. RESULTS: The incremental cost-effectiveness ratio (ICER) with 3% discount rate (euro/QALY) for aflibercept compared with monthly bevacizumab was 1 801 228 and when compared with ranibizumab given as needed, the ICER was minus 3 716 943. The sensitivity analysis showed that a change of 20% of the estimated model parameters or a longer follow-up period did not influence these conclusions. CONCLUSION: A two-eye Markov transition model was developed to analyse the cost-effectiveness of wet AMD treatment, as quality of life years (QALYs) are largely based on the visual acuity of the better-seeing eye. Monthly injected bevacizumab was the most cost-effective treatment and monthly ranibizumab the least effective.",2016-11,26/11/2018 12:49,14/04/2020 08:35,,652-656,,7,94,,Acta Ophthalmol,,,,,,,,eng,(c) 2016 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.,,,,,,PMID: 27481048,,,,"Humans; Quality-Adjusted Life Years; Female; Male; *Cost-Benefit Analysis; Aged; Markov Chains; Aged, 80 and over; cost-effectiveness; Health Expenditures; aflibercept; Angiogenesis Inhibitors/administration & dosage/*economics; bevacizumab; Bevacizumab/administration & dosage/economics; Drug Administration Schedule; exudative age-related macular degeneration; Finland; Hospitals, University; Intravitreal Injections; ranibizumab; Ranibizumab/administration & dosage/economics; Receptors, Vascular Endothelial Growth Factor/administration & dosage; Recombinant Fusion Proteins/administration & dosage/economics; Vascular Endothelial Growth Factor A/antagonists & inhibitors; Wet Macular Degeneration/drug therapy/*economics; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4U7D3M7X,journalArticle,2016,"Dahabreh, Issa J.; Trikalinos, Thomas A.; Balk, Ethan M.; Wong, John B.",Recommendations for the Conduct and Reporting of Modeling and Simulation Studies in Health Technology Assessment.,Annals of internal medicine,,1539-3704 0003-4819,10.7326/M16-0161,,"Models and simulations are valuable tools for addressing the uncertainty, tradeoffs, and heterogeneous preferences that complicate research questions in health technology assessment. This article presents recommendations for the conduct and reporting of modeling and simulation studies based on a systematic review of published recommendation statements, a survey of Web sites of international health technology assessment organizations, and input from experts and other stakeholders. The recommendations apply to mathematical models that represent structural relationships among model components and integrate information from multiple sources; they address model identification, estimation, verification, and validation, as well as the conduct of sensitivity, stability, and uncertainty analyses. They are organized into model conceptualization and structure, data, model assessment and consistency, and interpreting and reporting results. They should contribute to increased use and better conduct and reporting of modeling and simulation studies in health technology assessment.",18/10/2016,26/11/2018 12:49,14/04/2020 08:34,,575-581,,8,165,,Ann Intern Med,,,,,,,,eng,,,,,,,PMID: 27750326,,,,"Humans; Reproducibility of Results; *Models, Theoretical; Data Interpretation, Statistical; Technology Assessment, Biomedical/*methods; Evidence-Based Medicine/methods; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, AKNJSTPH,journalArticle,2018,"Asamoah, Daniel A.; Sharda, Ramesh; Rude, Howard N.; Doran, Derek",RFID-based information visibility for hospital operations: exploring its positive effects using discrete event simulation.,Health care management science,,1386-9620 1386-9620,10.1007/s10729-016-9386-y,,"Long queues and wait times often occur at hospitals and affect smooth delivery of health services. To improve hospital operations, prior studies have developed scheduling techniques to minimize patient wait times. However, these studies lack in demonstrating how such techniques respond to real-time information needs of hospitals and efficiently manage wait times. This article presents a multi-method study on the positive impact of providing real-time scheduling information to patients using the RFID technology. Using a simulation methodology, we present a generic scenario, which can be mapped to real-life situations, where patients can select the order of laboratory services. The study shows that information visibility offered by RFID technology results in decreased wait times and improves resource utilization. We also discuss the applicability of the results based on field interviews granted by hospital clinicians and administrators on the perceived barriers and benefits of an RFID system.",2018-09,26/11/2018 12:49,14/04/2020 08:34,,305-316,,3,21,,Health Care Manag Sci,,,,,,,,eng,,,,,,,PMID: 27734237,,,,"Humans; Computer Simulation; Time Factors; Efficiency, Organizational; Hospitals; Discrete event simulation; 00; *Appointments and Schedules; Field interview; Health care; Hospital Administration/methods; Information visibility; Radio Frequency Identification Device/*methods; RFID; Scheduling; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HCSUCUWW,journalArticle,2018,"Alibrahim, Abdullah; Wu, Shinyi",An agent-based simulation model of patient choice of health care providers in accountable care organizations.,Health care management science,,1386-9620 1386-9620,10.1007/s10729-016-9383-1,,"Accountable care organizations (ACO) in the United States show promise in controlling health care costs while preserving patients' choice of providers. Understanding the effects of patient choice is critical in novel payment and delivery models like ACO that depend on continuity of care and accountability. The financial, utilization, and behavioral implications associated with a patient's decision to forego local health care providers for more distant ones to access higher quality care remain unknown. To study this question, we used an agent-based simulation model of a health care market composed of providers able to form ACO serving patients and embedded it in a conditional logit decision model to examine patients capable of choosing their care providers. This simulation focuses on Medicare beneficiaries and their congestive heart failure (CHF) outcomes. We place the patient agents in an ACO delivery system model in which provider agents decide if they remain in an ACO and perform a quality improving CHF disease management intervention. Illustrative results show that allowing patients to choose their providers reduces the yearly payment per CHF patient by $320, reduces mortality rates by 0.12 percentage points and hospitalization rates by 0.44 percentage points, and marginally increases provider participation in ACO. This study demonstrates a model capable of quantifying the effects of patient choice in a theoretical ACO system and provides a potential tool for policymakers to understand implications of patient choice and assess potential policy controls.",2018-03,26/11/2018 12:49,14/04/2020 08:34,,131-143,,1,21,,Health Care Manag Sci,,,,,,,,eng,,,,,,,PMID: 27704322,,,,"Humans; United States; Quality of Health Care; Treatment Outcome; Female; Male; Aged, 80 and over; Computer Simulation; *Choice Behavior; Medicare; Hospitalization; Patients; 1; Accountable care organization; Accountable Care Organizations/*economics/*utilization; Agent-based simulation model; Congestive heart failure; Health policy simulation; Heart Failure/economics/mortality/therapy; Patient choice; agent based; 310",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QNCLG6Y5,journalArticle,2016,"Lilly, Mary LuAnne; Hermanns, Melinda; Crawley, Bill",Clinical Simulation in Psychiatric-Mental Health Nursing: Post-Graduation Follow Up.,Journal of psychosocial nursing and mental health services,,0279-3695 0279-3695,10.3928/02793695-20160920-07,,"In psychiatric-mental health, creating an innovative strategy to help students learn content that may not be frequently seen in a clinical setting is challenging. Thus, simulation helps narrow this gap. Using Kirkpatrick and Kirkpatrick's model of evaluation to guide the current study, faculty contacted baccalaureate nursing program graduates who completed a psychiatric-mental health clinical simulation scenario featuring a hanging suicide and wrist cutting suicide attempt scenario in the ""Behind the Door"" series as part of the clinical component of their undergraduate psychiatric-mental health course. Eleven nurses responded to a survey regarding their post-graduate encounters with these types of clinical situations, and their perception of recall and application of knowledge and skills acquired during the simulation experience to the clinical situation. Nursing graduates' responses are expressed through three major themes: emotional, contextual/behavioral, and assessment outcomes. Data from the survey indicate that nursing graduates perceived the ""Behind the Door"" simulations as beneficial to nursing practice. This perception is important in evaluating knowledge transfer from a simulation experience as a student into application in nursing practice. [Journal of Psychosocial Nursing and Mental Health Services, 54(10), 40-45.].",01/10/2016,26/11/2018 12:49,14/04/2020 08:34,,40-46,,10,54,,J Psychosoc Nurs Ment Health Serv,,,,,,,,eng,"Copyright 2016, SLACK Incorporated.",,,,,,PMID: 27699425,,,,"Humans; Adult; Female; Male; Middle Aged; *Patient Simulation; Follow-Up Studies; Education, Nursing, Baccalaureate; Psychiatric Nursing/*education; 00; *Nurse's Role; Self-Injurious Behavior; Suicide, Attempted/*psychology; Wrist Injuries/nursing; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RJ7G3Z3J,journalArticle,2017,"Williams, Claire; Lewsey, James D.; Mackay, Daniel F.; Briggs, Andrew H.",Estimation of Survival Probabilities for Use in Cost-effectiveness Analyses: A Comparison of a Multi-state Modeling Survival Analysis Approach with Partitioned Survival and Markov Decision-Analytic Modeling.,Medical decision making : an international journal of the Society for Medical Decision Making,,1552-681X 0272-989X,10.1177/0272989X16670617,,"Modeling of clinical-effectiveness in a cost-effectiveness analysis typically involves some form of partitioned survival or Markov decision-analytic modeling. The health states progression-free, progression and death and the transitions between them are frequently of interest. With partitioned survival, progression is not modeled directly as a state; instead, time in that state is derived from the difference in area between the overall survival and the progression-free survival curves. With Markov decision-analytic modeling, a priori assumptions are often made with regard to the transitions rather than using the individual patient data directly to model them. This article compares a multi-state modeling survival regression approach to these two common methods. As a case study, we use a trial comparing rituximab in combination with fludarabine and cyclophosphamide v. fludarabine and cyclophosphamide alone for the first-line treatment of chronic lymphocytic leukemia. We calculated mean Life Years and QALYs that involved extrapolation of survival outcomes in the trial. We adapted an existing multi-state modeling approach to incorporate parametric distributions for transition hazards, to allow extrapolation. The comparison showed that, due to the different assumptions used in the different approaches, a discrepancy in results was evident. The partitioned survival and Markov decision-analytic modeling deemed the treatment cost-effective with ICERs of just over pound16,000 and pound13,000, respectively. However, the results with the multi-state modeling were less conclusive, with an ICER of just over pound29,000. This work has illustrated that it is imperative to check whether assumptions are realistic, as different model choices can influence clinical and cost-effectiveness results.",2017-05,26/11/2018 12:49,14/04/2020 08:35,,427-439,,4,37,,Med Decis Making,,,,,,,,eng,,,,,,,PMID: 27698003 PMCID: PMC5424853,,,,"Humans; Quality-Adjusted Life Years; Decision Support Techniques; *Markov Chains; *cost-effectiveness analysis; *Markov models; *oncology; *survival analysis; *Survival Analysis; Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Cost-Benefit Analysis/*methods; Data Interpretation, Statistical; Disease-Free Survival; Leukemia, Lymphocytic, Chronic, B-Cell/drug therapy/mortality; Probability; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YCXVNUEA,journalArticle,2016,"Ulloa-Perez, Ernesto; Mohar-Betancourt, Alejandro; Reynoso-Noveron, Nancy",Estimation of the Cost-Effectiveness of Breast Cancer Screening Using Mammography in Mexico Through a Simulation.,Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion,,0034-8376 0034-8376,,,"BACKGROUND: Currently, breast cancer is the most prevalent tumor among Mexican women. Screening methods such as mammography could potentially reduce the health and economic burden of breast cancer; however, its risk-benefit balance is still unclear. OBJECTIVE: To estimate the cost-effectiveness of different breast cancer screening programs using mammography in Mexico and to contribute to the decision-making process on this preventive measure. METHODS: A simulation study was performed using population data and incidence rates. Several screening programs were assessed using the cost-effectiveness methodology recommended by the World Health Organization. RESULTS: The feasible recommended screening program has an examination schedule periodicity of every three years, with a population coverage of 0, 15, 18, 20, 25, 20, 18, and 0% for the age groups of",2016-08,26/11/2018 12:49,14/04/2020 08:35,,184-191,,4,68,,Rev Invest Clin,,,,,,,,eng,,,,,,,PMID: 27623037,,,,*Health Policy; Humans; Cost-Benefit Analysis; World Health Organization; Adult; Female; Middle Aged; Aged; Decision Making; Computer Simulation; Time Factors; Breast Neoplasms/*diagnosis/epidemiology/prevention & control; Mammography/economics/*methods; Mass Screening/economics/*methods; Mexico/epidemiology; 1; Dsicrete event simulation; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5YMLWESI,journalArticle,2016,"Palmer, Jennifer J.; Gilbert, Alice; Choy, Michelle; Blanchet, Karl",Circumventing 'free care' and 'shouting louder': using a health systems approach to study eye health system sustainability in government and mission facilities of north-west Tanzania.,Health research policy and systems,,1478-4505 1478-4505,10.1186/s12961-016-0137-9,,"BACKGROUND: Little is known about the contributions of faith-based organisations (FBOs) to health systems in Africa. In the specialist area of eye health, international and domestic Christian FBOs have been important contributors as service providers and donors, but they are also commonly critiqued as having developed eye health systems parallel to government structures which are unsustainable. METHODS: In this study, we use a health systems approach (quarterly interviews, a participatory sustainability analysis exercise and a social network analysis) to describe the strategies used by eye care practitioners in four hospitals of north-west Tanzania to navigate the government, church mission and donor rules that govern eye services delivery there. RESULTS: Practitioners in this region felt eye care was systemically neglected by government and therefore was 'all under the NGOs', but support from international donors was also precarious. Practitioners therefore adopted four main strategies to improve the sustainability of their services: (1) maintain 'sustainability funds' to retain financial autonomy over income; (2) avoid granting government user fee exemptions to elderly patients who are the majority of service users; (3) expand or contract outreach services as financial circumstances change; and (4) access peer support for problem-solving and advocacy. Mission-based eye teams had greater freedom to increase their income from user fees by not implementing government policies for 'free care'. Teams in all hospitals, however, found similar strategies to manage their programmes even when their management structures were unique, suggesting the importance of informal rules shared through a peer network in governing eye care in this pluralistic health system. CONCLUSIONS: Health systems research can generate new evidence on the social dynamics that cross public and private sectors within a local health system. In this area of Tanzania, Christian FBOs' investments are important, not only in terms of the population health outcomes achieved by teams they support, but also in the diversity of organisational models they contribute to in the wider eye health system, which facilitates innovation.",09/09/2016,26/11/2018 12:49,14/04/2020 08:35,,68,,1,14,,Health Res Policy Syst,,,,,,,,eng,,,,,,,PMID: 27612454 PMCID: PMC5017067,,,,"Humans; Public Sector; Aged; Systems Analysis; *Healthcare Financing; Tanzania; Health Personnel; Health Services Research/methods; Government Programs; Developing Countries; Income; 00; Sustainability; *Delivery of Health Care/economics/organization & administration; *Government; *Hospitals, Public; *Hospitals, Religious/economics; *Ophthalmology; *Religious Missions; Cataract surgeon; Christianity; Economics, Hospital; Eye; Eye care; Eye Diseases/therapy; Eye health system; Faith-based organisations; Fees and Charges; Health systems research; Organizations; Private Sector; User fees; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FXAGV25E,journalArticle,2016,"Shachak, Aviv; Elamrousy, Samer; Borycki, Elizabeth M.; Domb, Sharon; Kushniruk, Andre W.","Towards Educational Electronic Health Records (EHRs): A Design Process for Integrating EHRs, Simulation, and Video Tutorials.",Studies in health technology and informatics,,0926-9630 0926-9630,,,"Electronic health records (EHRs) are becoming ubiquitous in healthcare practice. However, their use in medical education has been slower to catch on and a new category of EHRs is beginning to emerge known as eduEHRs. These systems allow learners to explore and experiment with EHRs in the context of medical education. However, current eduEHRs have limitations, such as a lack of dynamic interaction built-in that would mimic real-world use of these tools. To overcome this, the integration of eduEHRs with software and tools such as video simulations and tutorials has considerable promise. In this paper we describe a new design process for integrating EHRs, simulations, and video tutorials.",2016,26/11/2018 12:49,14/04/2020 08:35,,624-628,,,228,,Stud Health Technol Inform,,,,,,,,eng,,,,,,,PMID: 27577459,,,,"Humans; Systems Integration; User-Computer Interface; Teaching Materials; 00; Health Information Exchange; Education, Medical/*methods; *Electronic Health Records/organization & administration/standards; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WP6I3IQ2,journalArticle,2016,"Chao, Chia-An",The impact of electronic health records on collaborative work routines: A narrative network analysis.,International journal of medical informatics,,1872-8243 1386-5056,10.1016/j.ijmedinf.2016.06.019,,"PURPOSE: This study examined collaborative work routines and changes after the implementation of a perinatal EHR. The change process and underlying drivers were analyzed to offer insight into why changes - intended or unintended - did or did not occur and their implications for EHR design and implementation. METHODS: This mixed-method case study included both qualitative and quantitative information. Pre- and post-implementation observations took place over an 18-month period totaling 90h. Formal and informal interviews with administrative and clinical staff, pre- and post-implementation surveys, project meeting observations, and artifact review supplemented data gathered from the observations. Workflow and narrative network analyses of work routines were used to identify changes pre- and post-EHR and to represent different perspectives of work routines. RESULTS: EHR improved documentation efficiency and in- and out-patient information exchange, but increased variability in documentation. Some variabilities were institutionally sanctioned or tolerated, but other variabilities - while ingenious and emblematic of the generative nature of routines enabled by the EHR - were problematic. EHR's support for clinician communication and coordination was limited and its cognitive support insufficient. In some cases, EHR increased cognitive load as the unlocalized EHR scattered information, and the lengthy printouts contributed to information fragmentation and made information retrieval more difficult. CONCLUSIONS: The process of the EHR implementation and the changes observed was the confluence of three factors: resource constraint - in particular EHR expertise and experience - not uncommon in many community hospitals; the functional properties of the EHR focusing on information aggregation, storage, and retrieval; and the extant culture and practice of healthcare emphasizing autonomy and flexibility. While collaborative and communication changes were prompted by EHR implementation, the system played a minimal role in mediating changes. Instead, changes in work routines were negotiated between the administration and clinicians, and jointly refined over time.",2016-10,26/11/2018 12:49,14/04/2020 08:34,,100-111,,,94,,Int J Med Inform,,,,,,,,eng,Copyright (c) 2016 Elsevier Ireland Ltd. All rights reserved.,,,,,,PMID: 27573317,,,,Humans; *Quality of Health Care; Communication; *Cooperative Behavior; *Electronic Health Records; Workflow; 1; *Collaboration; *Computerized patient documentation; *Electronic health record; *Narrative network; *Organizational routine; Documentation/standards; Information Storage and Retrieval; Narration; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, R4R3SG7I,journalArticle,2016,"Zhao, Kang; Wang, Xi; Cha, Sarah; Cohn, Amy M.; Papandonatos, George D.; Amato, Michael S.; Pearson, Jennifer L.; Graham, Amanda L.",A Multirelational Social Network Analysis of an Online Health Community for Smoking Cessation.,Journal of medical Internet research,,1438-8871 1438-8871,10.2196/jmir.5985,,"BACKGROUND: Online health communities (OHCs) provide a convenient and commonly used way for people to connect around shared health experiences, exchange information, and receive social support. Users often interact with peers via multiple communication methods, forming a multirelational social network. Use of OHCs is common among smokers, but to date, there have been no studies on users' online interactions via different means of online communications and how such interactions are related to smoking cessation. Such information can be retrieved in multirelational social networks and could be useful in the design and management of OHCs. OBJECTIVE: To examine the social network structure of an OHC for smoking cessation using a multirelational approach, and to explore links between subnetwork position (ie, centrality) and smoking abstinence. METHODS: We used NetworkX to construct 4 subnetworks based on users' interactions via blogs, group discussions, message boards, and private messages. We illustrated topological properties of each subnetwork, including its degree distribution, density, and connectedness, and compared similarities among these subnetworks by correlating node centrality and measuring edge overlap. We also investigated coevolution dynamics of this multirelational network by analyzing tie formation sequences across subnetworks. In a subset of users who participated in a randomized, smoking cessation treatment trial, we conducted user profiling based on users' centralities in the 4 subnetworks and identified user groups using clustering techniques. We further examined 30-day smoking abstinence at 3 months postenrollment in relation to users' centralities in the 4 subnetworks. RESULTS: The 4 subnetworks have different topological characteristics, with message board having the most nodes (36,536) and group discussion having the highest network density (4.35x10(-3)). Blog and message board subnetworks had the most similar structures with an in-degree correlation of .45, out-degree correlation of .55, and Jaccard coefficient of .23 for edge overlap. A new tie in the group discussion subnetwork had the lowest probability of triggering subsequent ties among the same two users in other subnetworks: 6.33% (54,142/855,893) for 2-tie sequences and 2.13% (18,207/855,893) for 3-tie sequences. Users' centralities varied across the 4 subnetworks. Among a subset of users enrolled in a randomized trial, those with higher centralities across subnetworks generally had higher abstinence rates, although high centrality in the group discussion subnetwork was not associated with higher abstinence rates. CONCLUSIONS: A multirelational approach revealed insights that could not be obtained by analyzing the aggregated network alone, such as the ineffectiveness of group discussions in triggering social ties of other types, the advantage of blogs, message boards, and private messages in leading to subsequent social ties of other types, and the weak connection between one's centrality in the group discussion subnetwork and smoking abstinence. These insights have implications for the design and management of online social networks for smoking cessation.",25/08/2016,26/11/2018 12:49,14/04/2020 08:35,,e233,,8,18,,J Med Internet Res,,,,,,,,eng,,,,,,,PMID: 27562640 PMCID: PMC5016624,,,,"Humans; *Social Networking; *Social Support; Longitudinal Studies; *Internet; 1; *community networks; *smoking cessation; *social networks; Randomized Controlled Trials as Topic/methods; Smoking Cessation/*methods/psychology; Telemedicine/*methods; Therapy, Computer-Assisted/*methods; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IVUP63W8,journalArticle,2016,"Newell, Barry; Siri, Jose",A role for low-order system dynamics models in urban health policy making.,Environment international,,1873-6750 0160-4120,10.1016/j.envint.2016.08.003,,"Cities are complex adaptive systems whose responses to policy initiatives emerge from feedback interactions between their parts. Urban policy makers must routinely deal with both detail and dynamic complexity, coupled with high levels of diversity, uncertainty and contingency. In such circumstances, it is difficult to generate reliable predictions of health-policy outcomes. In this paper we explore the potential for low-order system dynamics (LOSD) models to make a contribution towards meeting this challenge. By definition, LOSD models have few state variables (6 months' duration) VLUs from a payer's perspective. A Markov model was constructed to evaluate the cost and clinical benefits (healing and decreased infection rates) of the 2 treatment modalities over a 1-year period using data from 4 randomized, controlled clinical studies (RCTs) included in a recent Cochrane review and cost data from a recently published economic evaluation of VLUs. Costs were calculated using 2014 United States dollars; wound outcomes in- cluded complete healing in 212 patients reported in the Cochrane meta-analysis and quality-adjusted life years (QALYs), with utility values obtained from 200 patients with VLUs calculated using standard gamble. Treatment with CI over 1 year was $7,259 compared to $7,901 for SC. This resulted in a cost savings of $643/patient in favor of CI compared with SC. More patients treated with CI (61%) had their wounds healed compared to 54% treated with SC. Furthermore, patients treated with CI+SC experienced 6 additional ulcer-free weeks compared to persons treated with SC alone (ie, 25 ulcer- free weeks compared to 19 ulcer-free weeks, respectively). Overall, CI resulted in 0.03 more QALYs (ie, 0.86 QALYs compared to 0.83 for SC). The use of CI in addition to SC compared to SC alone over 52 weeks resulted in more wounds healed and more QALYs along with a decrease of overall costs The results of this study suggest CI is cost effective com- pared to SC alone in the management of patients with chronic VLUs. Prospective, controlled clinical studies are needed to elucidate the effect and cost effectiveness of CI on VLUs with and without signs of infection as compared to SC, other antiseptics, and more advanced topical treatment modalities.",2016-06,26/11/2018 12:49,14/04/2020 08:35,,26-40,,6,62,,Ostomy Wound Manage,,,,,,,,eng,,,,,,,PMID: 27356144,,,,Humans; Decision Support Techniques; 00; Anti-Bacterial Agents/therapeutic use; *Treatment Outcome; Cost-Benefit Analysis/*standards; Iodophors/economics/pharmacology/*therapeutic use; Leg Ulcer/drug therapy/physiopathology; Occlusive Dressings/standards; Varicose Ulcer/*drug therapy/economics/physiopathology; Wound Healing/drug effects; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7LENMW2R,journalArticle,2016,"Hawkins, A.; Tredgett, K.",Use of high-fidelity simulation to improve communication skills regarding death and dying: a qualitative study.,BMJ supportive & palliative care,,2045-4368 2045-435X,10.1136/bmjspcare-2015-001081,,"OBJECTIVES: The objectives of this study were to explore medical students' experiences of communicating with patients and their carers about death and dying, and to assess whether using high-fidelity simulation improved students' confidence in discussing cardiopulmonary resuscitation. METHODS: This qualitative study was carried out at a hospital in the south of England. Participants were 7 final-year medical students. Tutorials were developed using high-fidelity simulation to teach communication skills regarding discussion of cardiopulmonary resuscitation with patients and carers. Scenarios involved a simulated ward environment, a high-fidelity simulation mannequin and actor playing the role of a carer. Data were collected through joint interviews carried out by one researcher which were audio recorded and transcribed verbatim. The same researcher analysed the data using framework analysis. RESULTS: Students reported a lack of experience observing conversations with patients and carers about death and dying. They also reported a lack of opportunities to interact with dying patients during their training. Barriers reported by students included healthcare professionals' and patients' attitudes. Students reported a lack of confidence and preparedness to have consultations with patients and carers about death, dying and cardiopulmonary resuscitation as junior doctors. They perceived role-play scenarios observed by their peers to be stressful, and this detracted from the learning experience. Students reported that the high-fidelity simulation scenarios were more realistic than low-fidelity ('role-play') scenarios. This improved the learning gained from the sessions and improved confidence among some students. CONCLUSIONS: This study has suggested that high-fidelity simulation may be a useful adjunct for undergraduate communication skills training in palliative medicine. Further research is required to assess whether improvements in confidence described by students in this study translate to discernible improvements in competence, and whether using high-fidelity simulation in this setting is cost-effective.",2016-12,26/11/2018 12:49,14/04/2020 08:34,,474-478,,4,6,,BMJ Support Palliat Care,,,,,,,,eng,Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.,,,,,,PMID: 27316636,,,,"Humans; Adult; Clinical Competence; Female; Male; Young Adult; *Physician-Patient Relations; Qualitative Research; High Fidelity Simulation Training/*methods; simulation; Patient Simulation; education; 00; communication; Education, Medical, Undergraduate/*methods; Health Communication/*methods; Cardiopulmonary Resuscitation/*education; Palliative Care/methods; Terminal Care/*methods; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BQDD5XP8,journalArticle,2016,"Castle, David; Crosse, Caroline; Morgain, Dea; McDowell, Caitlin; Rossell, Susan; Thomas, Neil; Phillipou, Andrea; Gilbert, Monica; Moore, Gaye; Fossey, Ellie; Harvey, Carol",Helping people with a mental illness obtain work: the Health Optimisation Program for Employment.,Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists,,1440-1665 1039-8562,10.1177/1039856216654400,,"OBJECTIVE: Inclusion in work and education remains problematic for many people with a mental illness. We describe a structured programme - the Health Optimisation Program for Employment - that supported people with a mental illness to gain employment or commence studies. METHOD: Twenty hours of the Health Optimisation Program for Employment were delivered to 600 individuals. Participants were asked to complete an evaluation survey encompassing vocational status and ratings of self-efficacy. RESULTS: Of the 364 participants who completed the baseline assessment, 168 responded to the evaluation survey 6 months after the delivery of the Health Optimisation Program for Employment. Of these, 21.5% had started a new job, while a further 42.8% were either volunteering or studying. Satisfaction with the programme was high and self-efficacy ratings improved significantly over the short term only. CONCLUSIONS: The Health Optimisation Program for Employment requires further evaluation using rigorous scientific methodology but these initial results are encouraging in terms of vocational attainment for people with a mental illness, in the Australian context.",2016-08,26/11/2018 12:49,14/04/2020 08:34,,337-341,,4,24,,Australas Psychiatry,,,,,,,,eng,(c) The Royal Australian and New Zealand College of Psychiatrists 2016.,,,,,,PMID: 27307449,,,,"Humans; Surveys and Questionnaires; Adult; Female; Male; Middle Aged; Australia; Health Promotion/methods; 00; self-management; Self Efficacy; self-efficacy; employment; Employment, Supported/*methods; Mental Disorders/*psychology/*rehabilitation; mental illness; peer educator; psychoeducation; vocational rehabilitation; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DQEAVF9J,journalArticle,2016,"Moore, Shirley M.; Jones, Lenette; Alemi, Farrokh",Family self-tailoring: Applying a systems approach to improving family healthy living behaviors.,Nursing outlook,,1528-3968 0029-6554,10.1016/j.outlook.2016.05.006,,"The adoption and maintenance of healthy living behaviors by individuals and families is a major challenge. We describe a new model of health behavior change, SystemCHANGE (SC), which focuses on the redesign of family daily routines using system improvement methods. In the SC intervention, families are taught a set of skills to engage in a series of small, family self-designed experiments to test ideas to change their daily routines. The family system-oriented changes brought about by these experiments build healthy living behaviors into family daily routines so that these new behaviors happen as a matter of course, despite wavering motivation, willpower, or personal effort on the part of individuals. Case stories of the use of SC to improve family healthy living behaviors are provided. Results of several pilot tests of SC indicate its potential effectiveness to change health living behaviors across numerous populations.",2016-08,26/11/2018 12:49,14/04/2020 08:35,,306-311,,4,64,,Nurs Outlook,,,,,,,,eng,Copyright (c) 2016 Elsevier Inc. All rights reserved.,,,,,,PMID: 27301950 PMCID: PMC4947020,,,,"Humans; Adult; Female; Male; Middle Aged; Young Adult; Aged; Child; Adolescent; Aged, 80 and over; *Health Behavior; *Life Style; *Motivation; Health Promotion/*methods; 1; *Attitude to Health; *Behavior change interventions; *Family lifestyle change; *Habit building; *Healthy living habits; *Process improvement; *System change; *System improvement; Family/*psychology; Self Care/*psychology; system approach; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, E3MIG6ZY,journalArticle,2016,"Kolominsky-Rabas, Peter L.; Kriza, Christine; Djanatliev, Anatoli; Meier, Florian; Uffenorde, Steffen; Radeleff, Jannis; Baumgartel, Philipp; Leb, Ines; Sedlmayr, Martin; Gaiser, Sebastian; Adamson, Philip B.",Health Economic Impact of a Pulmonary Artery Pressure Sensor for Heart Failure Telemonitoring: A Dynamic Simulation.,Telemedicine journal and e-health : the official journal of the American Telemedicine Association,,1556-3669 1530-5627,10.1089/tmj.2015.0226,,"AIMS: Recently, a permanently implantable wireless system, designed to monitor and manage pulmonary artery (PA) pressures remotely, demonstrated significant reductions in heart failure (HF) hospitalizations in high-risk symptomatic patients, regardless of ejection fraction. The objectives of this study were to simulate the estimated clinical and economic impact in Germany of generalized use of this PA pressure monitoring system considering reductions of HF hospitalizations and the improvement in Quality of Life. MATERIALS AND METHODS: Based on the Prospective Health Technology Assessment approach, we simulated the potential of the widespread application of PA pressure monitoring on the German healthcare system for the period 2009-2021. RESULTS: This healthcare economic simulation formulated input assumptions based on results from the CHAMPION Trial, a multicenter, prospective, randomized controlled U.S. trial that demonstrated a 37% reduction of hospitalizations in persistently symptomatic previous HF patients. Based on these results, an estimated 114,800 hospitalizations would expected to be avoided. This effect would potentially save an estimated euro522 million, an equivalent of $575 million, during the entire simulation period. CONCLUSION: This healthcare economic modeling of the PA pressure monitoring system's impact demonstrates substantial clinical and economic benefits in the German healthcare system.",2016-10,26/11/2018 12:49,14/04/2020 08:34,,798-808,,10,22,,Telemed J E Health,,,,,,,,eng,,,,,,,PMID: 27285946,,,,"Humans; Female; Male; Middle Aged; Aged; Quality of Life; Aged, 80 and over; Computer Simulation; Prospective Studies; Germany; 00; Hospitalization/economics; *cardiology/cardiovascular disease; *home health monitoring; *Pulmonary Artery; *telecardiology; *telehealth; *telemedicine; Blood Pressure Monitoring, Ambulatory/economics/instrumentation/*methods; Heart Failure/*economics/*physiopathology; Remote Sensing Technology/economics/instrumentation/*methods; Telemedicine/economics/instrumentation/*methods; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JE7WLM4V,journalArticle,2016,"Montz, Ellen; Layton, Tim; Busch, Alisa B.; Ellis, Randall P.; Rose, Sherri; McGuire, Thomas G.",Risk-Adjustment Simulation: Plans May Have Incentives To Distort Mental Health And Substance Use Coverage.,Health affairs (Project Hope),,1544-5208 0278-2715,10.1377/hlthaff.2015.1668,,"Under the Affordable Care Act, the risk-adjustment program is designed to compensate health plans for enrolling people with poorer health status so that plans compete on cost and quality rather than the avoidance of high-cost individuals. This study examined health plan incentives to limit covered services for mental health and substance use disorders under the risk-adjustment system used in the health insurance Marketplaces. Through a simulation of the program on a population constructed to reflect Marketplace enrollees, we analyzed the cost consequences for plans enrolling people with mental health and substance use disorders. Our assessment points to systematic underpayment to plans for people with these diagnoses. We document how Marketplace risk adjustment does not remove incentives for plans to limit coverage for services associated with mental health and substance use disorders. Adding mental health and substance use diagnoses used in Medicare Part D risk adjustment is one potential policy step toward addressing this problem in the Marketplaces.",01/06/2016,26/11/2018 12:49,14/04/2020 08:35,,1022-1028,,6,35,,Health Aff (Millwood),,,,,,,,eng,"Project HOPE-The People-to-People Health Foundation, Inc.",,,,,,PMID: 27269018 PMCID: PMC5027954,,,,"Humans; United States; Adult; Female; Male; *Computer Simulation; Chronic Disease/economics; *Motivation; 1; *Adverse Selection; *Marketplace; *Mental Health/Substance Abuse; *Risk Adjustment; Health Insurance Exchanges/economics; Insurance Coverage/economics; Insurance, Health/economics/legislation & jurisprudence; Mental Disorders/*economics; Patient Protection and Affordable Care Act/economics; Risk Adjustment/*economics/legislation & jurisprudence; Substance-Related Disorders/*economics; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, SG8ULB5J,journalArticle,2016,"Deutsch, Ellen S.; Dong, Yue; Halamek, Louis P.; Rosen, Michael A.; Taekman, Jeffrey M.; Rice, John",Leveraging Health Care Simulation Technology for Human Factors Research: Closing the Gap Between Lab and Bedside.,Human factors,,1547-8181 0018-7208,10.1177/0018720816650781,,"OBJECTIVE: We describe health care simulation, designed primarily for training, and provide examples of how human factors experts can collaborate with health care professionals and simulationists-experts in the design and implementation of simulation-to use contemporary simulation to improve health care delivery. BACKGROUND: The need-and the opportunity-to apply human factors expertise in efforts to achieve improved health outcomes has never been greater. Health care is a complex adaptive system, and simulation is an effective and flexible tool that can be used by human factors experts to better understand and improve individual, team, and system performance within health care. METHOD: Expert opinion is presented, based on a panel delivered during the 2014 Human Factors and Ergonomics Society Health Care Symposium. RESULTS: Diverse simulators, physically or virtually representing humans or human organs, and simulation applications in education, research, and systems analysis that may be of use to human factors experts are presented. Examples of simulation designed to improve individual, team, and system performance are provided, as are applications in computational modeling, research, and lifelong learning. CONCLUSION: The adoption or adaptation of current and future training and assessment simulation technologies and facilities provides opportunities for human factors research and engineering, with benefits for health care safety, quality, resilience, and efficiency. APPLICATION: Human factors experts, health care providers, and simulationists can use contemporary simulation equipment and techniques to study and improve health care delivery.",2016-11,26/11/2018 12:49,14/04/2020 08:34,,1082-1095,,7,58,,Hum Factors,,,,,,,,eng,"(c) 2016, Human Factors and Ergonomics Society.",,,,,,PMID: 27268996,,,,"Humans; *Patient Simulation; *simulation; *Delivery of Health Care; *Ergonomics; *health care; 00; *patient safety; *health care quality; *Models, Anatomic; *systems; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LKZNZXPR,journalArticle,2016,"Pitt, Michael B.; Gladding, Sophia P.; Butteris, Sabrina M.",Using Simulation for Global Health Preparation.,Pediatrics,,1098-4275 0031-4005,10.1542/peds.2015-4500,,,2016-05,26/11/2018 12:49,14/04/2020 08:35,,,,5,137,,Pediatrics,,,,,,,,eng,,,,,,,PMID: 27244823,,,,Humans; United States; Curriculum; Internship and Residency/*methods; Simulation Training/*methods; 00; Pediatrics/*education; Global Health/*education; Travel; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, I62GQKQG,journalArticle,2016,"Topp, Stephanie M.; Moonga, Clement N.; Luo, Nkandu; Kaingu, Michael; Chileshe, Chisela; Magwende, George; Heymann, S. Jody; Henostroza, German",Exploring the drivers of health and healthcare access in Zambian prisons: a health systems approach.,Health policy and planning,,1460-2237 0268-1080,10.1093/heapol/czw059,,"BACKGROUND: Prison populations in sub-Saharan Africa (SSA) experience a high burden of disease and poor access to health care. Although it is generally understood that environmental conditions are dire and contribute to disease spread, evidence of how environmental conditions interact with facility-level social and institutional factors is lacking. This study aimed to unpack the nature of interactions and their influence on health and healthcare access in the Zambian prison setting. METHODS: We conducted in-depth interviews of a clustered random sample of 79 male prisoners across four prisons, as well as 32 prison officers, policy makers and health care workers. Largely inductive thematic analysis was guided by the concepts of dynamic interaction and emergent behaviour, drawn from the theory of complex adaptive systems. RESULTS: A majority of inmates, as well as facility-based officers reported anxiety linked to overcrowding, sanitation, infectious disease transmission, nutrition and coercion. Due in part to differential wealth of inmates and their support networks on entering prison, and in part to the accumulation of authority and material wealth within prison, we found enormous inequity in the standard of living among prisoners at each site. In the context of such inequities, failure of the Zambian prison system to provide basic necessities (including adequate and appropriate forms of nutrition, or access to quality health care) contributed to high rates of inmate-led and officer-led coercion with direct implications for health and access to healthcare. CONCLUSIONS: This systems-oriented analysis provides a more comprehensive picture of the way resource shortages and human interactions within Zambian prisons interact and affect inmate and officer health. While not a panacea, our findings highlight some strategic entry-points for important upstream and downstream reforms including urgent improvement in the availability of human resources for health; strengthening of facility-based health services systems and more comprehensive pre-service health education for prison officers.",2016-11,26/11/2018 12:49,14/04/2020 08:35,,1250-1261,,9,31,,Health Policy Plan,,,,,,,,eng,(c) The Author 2016. Published by Oxford University Press in association with The London School of Hygiene and Tropical Medicine.,,,,,,PMID: 27220354 PMCID: PMC5035781,,,,"Humans; Delivery of Health Care/*standards; Male; Interviews as Topic; Quality of Health Care/*standards; Administrative Personnel; 00; Health Services Accessibility/*standards; *Prisons; Coercion; Disease Transmission, Infectious; health services; health system; nutrition; Nutritional Status; prisons,; Sanitation/standards; Zambia; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EA4ID5UU,journalArticle,2016,"Nordby, Halvor",Social simulation theory: a framework to explain nurses' understanding of patients' experiences of ill-health.,Nursing inquiry,,1440-1800 1320-7881,10.1111/nin.12134,,"A fundamental aim in caring practice is to understand patients' experiences of ill-health. These experiences have a qualitative content and cannot, unlike thoughts and beliefs with conceptual content, directly be expressed in words. Nurses therefore face a variety of interpretive challenges when they aim to understand patients' subjective perspectives on disease and illness. The article argues that theories on social simulation can shed light on how nurses manage to meet these challenges. The core assumption of social simulationism is that we do not understand other people by forming mental representations of how they think, but by putting ourselves in their situation in a more imaginative way. According to simulationism, any attempt to understand a patient's behavior is made on the basis of simulating what it is like to be that patient in the given context. The article argues that this approach to social interpretation can clarify how nurses manage to achieve aims of patient understanding, even when they have limited time to communicate and incomplete knowledge of patients' perspectives. Furthermore, simulation theory provides a normative framework for interpretation, in the sense that its theoretical assumptions constitute ideals for how nurses should seek to understand patients' experiences of illness.",2016-09,26/11/2018 12:49,14/04/2020 08:35,,232-243,,3,23,,Nurs Inq,,,,,,,,eng,(c) 2016 John Wiley & Sons Ltd.,,,,,,PMID: 27198752,,,,"Humans; Communication; *Clinical Competence; *Attitude of Health Personnel; Nursing Methodology Research; Empathy; *Nurse-Patient Relations; 00; Nursing Staff, Hospital/*psychology; *caring practice; *concept possession; *conceptions of illness; *nurse-patient interaction; *social simulation; *Social Theory; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NYBMLQK7,journalArticle,2016,"Jensen, Sanne",Clinical Simulation as an Evaluation Method in Health Informatics.,Studies in health technology and informatics,,0926-9630 0926-9630,,,"Safe work processes and information systems are vital in health care. Methods for design of health IT focusing on patient safety are one of many initiatives trying to prevent adverse events. Possible patient safety hazards need to be investigated before health IT is integrated with local clinical work practice including other technology and organizational structure. Clinical simulation is ideal for proactive evaluation of new technology for clinical work practice. Clinical simulations involve real end-users as they simulate the use of technology in realistic environments performing realistic tasks. Clinical simulation study assesses effects on clinical workflow and enables identification and evaluation of patient safety hazards before implementation at a hospital. Clinical simulation also offers an opportunity to create a space in which healthcare professionals working in different locations or sectors can meet and exchange knowledge about work practices and requirement needs. This contribution will discuss benefits and challenges of using clinical simulation, and will describe how clinical simulation fits into classical usability studies, how patient safety may benefit by use of clinical simulation, and it will describe the different steps of how to conduct clinical simulation. Furthermore a case study is presented.",2016,26/11/2018 12:49,14/04/2020 08:34,,152-164,,,222,,Stud Health Technol Inform,,,,,,,,eng,,,,,,,PMID: 27198100,,,,"Humans; Patient Safety; Personnel, Hospital; 00; Telemedicine/methods; *Evaluation Studies as Topic; Clinical Laboratory Techniques; Medical Informatics/methods/*organization & administration; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JEMWGD8Q,journalArticle,2016,"March, Christopher A.; Scholl, Gretchen; Dversdal, Renee K.; Richards, Matthew; Wilson, Leah M.; Mohan, Vishnu; Gold, Jeffrey A.",Use of Electronic Health Record Simulation to Understand the Accuracy of Intern Progress Notes.,Journal of graduate medical education,,1949-8357 1949-8357,10.4300/JGME-D-15-00201.1,,"Background With the widespread adoption of electronic health records (EHRs), there is a growing awareness of problems in EHR training for new users and subsequent problems with the quality of information present in EHR-generated progress notes. By standardizing the case, simulation allows for the discovery of EHR patterns of use as well as a modality to aid in EHR training. Objective To develop a high-fidelity EHR training exercise for internal medicine interns to understand patterns of EHR utilization in the generation of daily progress notes. Methods Three months after beginning their internship, 32 interns participated in an EHR simulation designed to assess patterns in note writing and generation. Each intern was given a simulated chart and instructed to create a daily progress note. Notes were graded for use of copy-paste, macros, and accuracy of presented data. Results A total of 31 out of 32 interns (97%) completed the exercise. There was wide variance in use of macros to populate data, with multiple macro types used for the same data category. Three-quarters of notes contained either copy-paste elements or the elimination of active medical problems from the prior days' notes. This was associated with a significant number of quality issues, including failure to recognize a lack of deep vein thrombosis prophylaxis, medications stopped on admission, and issues in prior discharge summary. Conclusions Interns displayed wide variation in the process of creating progress notes. Additional studies are being conducted to determine the impact EHR-based simulation has on standardization of note content.",2016-05,26/11/2018 12:51,14/04/2020 08:34,,237-240,,2,8,,J Grad Med Educ,,,,,,,,eng,,,,,,,PMID: 27168894 PMCID: PMC4857515,,,,Humans; Simulation Training; 00; Electronic Health Records/*standards; Internal Medicine/*education/methods; Internship and Residency/*methods/standards; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MNZFLCHP,journalArticle,2016,"Semwanga, Agnes Rwashana; Nakubulwa, Sarah; Adam, Taghreed",Applying a system dynamics modelling approach to explore policy options for improving neonatal health in Uganda.,Health research policy and systems,,1478-4505 1478-4505,10.1186/s12961-016-0101-8,,"BACKGROUND: The most recent reports on global trends in neonatal mortality continue to show alarmingly slow progress on improvements in neonatal mortality rates, with sub-Saharan Africa still lagging behind. This emphasised the urgent need to innovatively employ alternative solutions that take into account the intricate complexities of neonatal health and the health systems in which the various strategies operate. METHODS: In our first paper, we empirically explored the causes of the stagnating neonatal mortality in Uganda using a dynamic synthesis methodology (DSM) approach. In this paper, we completed the last three stages of DSM, which involved the development of a quantitative (simulation) model, using STELLA modelling software. We used statistical data to populate the model. Through brainstorming sessions with stakeholders, iterations to test and validate the model were undertaken. The different strategies and policy interventions that could possibly lower neonatal mortality rates were tested using what-if analysis. Sensitivity analysis was used to determine the strategies that could have a great impact on neonatal mortality. RESULTS: We developed a neonatal health simulation model (NEOSIM) to explore potential interventions that could possibly improve neonatal health within a health system context. The model has four sectors, namely population, demand for services, health of the mothers and choices of clinical care. It tests the effects of various interventions validated by a number of Ugandan health practitioners, including health education campaigns, free delivery kits, motorcycle coupons, kangaroo mother care, improving neonatal resuscitation and labour management skills, and interventions to improve the mothers health, i.e. targeting malaria, anaemia and tetanus. Among the tested interventions, the package with the highest impact on reducing neonatal mortality rates was a combination of the free delivery kits in a setting where delivery services were free and motorcycle coupons to take women to hospital during emergencies. CONCLUSIONS: This study presents a System Dynamics model with a broad and integrated view of the neonatal health system facilitating a deeper understanding of its current state and constraints and how these can be mitigated. A tool with a user friendly interface presents the dynamic nature of the model using 'what-if' scenarios, thus enabling health practitioners to discuss the consequences or effects of various decisions. Key findings of the research show that proposed interventions and their impact can be tested through simulation experiments thereby generating policies and interventions with the highest impact for improved healthcare service delivery.",04/05/2016,26/11/2018 12:51,14/04/2020 08:34,,35,,1,14,,Health Res Policy Syst,,,,,,,,eng,,,,,,,PMID: 27146327 PMCID: PMC4855338,,,,"*Health Policy; Humans; Female; Systems Analysis; Pregnancy; Models, Theoretical; *Delivery of Health Care; Infant; System dynamics; Infant, Newborn; Systems thinking; 1; Uganda; *Delivery, Obstetric; *Infant Health; *Infant Mortality; *Maternal Health Services; Causal loop diagram; Child health; Dynamic modelling; Maternal Health; Methods; Neonatal mortality; Policy options; X",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, B2R32S5K,journalArticle,2016,"Fonseca, Bruna de Paula Fonseca E.; Sampaio, Ricardo Barros; Fonseca, Marcus Vinicius de Araujo; Zicker, Fabio",Co-authorship network analysis in health research: method and potential use.,Health research policy and systems,,1478-4505 1478-4505,10.1186/s12961-016-0104-5,,"Scientific collaboration networks are a hallmark of contemporary academic research. Researchers are no longer independent players, but members of teams that bring together complementary skills and multidisciplinary approaches around common goals. Social network analysis and co-authorship networks are increasingly used as powerful tools to assess collaboration trends and to identify leading scientists and organizations. The analysis reveals the social structure of the networks by identifying actors and their connections. This article reviews the method and potential applications of co-authorship network analysis in health. The basic steps for conducting co-authorship studies in health research are described and common network metrics are presented. The application of the method is exemplified by an overview of the global research network for Chikungunya virus vaccines.",30/04/2016,26/11/2018 12:51,14/04/2020 08:34,,34,,1,14,,Health Res Policy Syst,,,,,,,,eng,,,,,,,PMID: 27138279 PMCID: PMC4852432,,,,Humans; *Bibliometrics; *Cooperative Behavior; 00; *Authorship; *Biomedical Research; *Research Personnel; *Science; Chikungunya virus; Viral Vaccines; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ILHJ82UI,journalArticle,2016,"Ben-Assuli, Ofir; Ziv, Amitai; Sagi, Doron; Ironi, Avinoah; Leshno, Moshe",Cost-Effectiveness Evaluation of EHR: Simulation of an Abdominal Aortic Aneurysm in the Emergency Department.,Journal of medical systems,,1573-689X 0148-5598,10.1007/s10916-016-0502-9,,"Health care organizations have installed electronic systems to increase efficiency in health care. Empirically assessing the cost-effectiveness of technologies to the health care system is a challenging and complex task. This study examined cost-effectiveness of additional clinical information supplied via an EHR system by simulating a case of abdominal aortic aneurysm devised and acted professionally by the Israel Center of Medical Simulation. We conducted a simulation-based study on physicians who were asked to treat a simulated patient for the prevalent medical scenario of hip and leg pain that actually corresponded to an abdominal aortic aneurysm. Half of the participating physicians from the Department of Emergency Medicine at Tel-Hashomer Hospital - Israel's largest - had access to an EHR system that integrates medical data from multiple health providers (community and hospitals) in addition to the local health record, and half did not. To model medical decision making, the results of the simulation were combined with a Markov Model within a decision tree. Cost-effectiveness was analyzed by comparing the effects of the admission/discharge decision in units of quality adjusted life years (QALYs) to the estimated costs. The results showed that using EHR in the ED increases the QALY of the patient and improves medical decision-making. The expenditure per patient for one QALY unit as a result of using the EHR was $1229, which is very cost-effective according to many accepted threshold values (less than all these values). Thus, using the EHR contributes to making a cost-effective decision in this specific but prevalent case.",2016-06,26/11/2018 12:51,14/04/2020 08:34,,141,,6,40,,J Med Syst,,,,,,,,eng,,,,,,,PMID: 27114352,,,,"Humans; Cost-Benefit Analysis; Markov Chains; Electronic Health Records; *Emergency Service, Hospital; Aortic Aneurysm, Abdominal/*therapy; Cost-effectiveness; Electronic health record; Emergency departments; Israel; Markov model; Medical Staff, Hospital/*education; QALY; Simulation Training/*economics; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TPRLP9NP,journalArticle,2016,"Kumar, Praveen; Chalise, Nishesh; Yadama, Gautam N.",Dynamics of sustained use and abandonment of clean cooking systems: study protocol for community-based system dynamics modeling.,International journal for equity in health,,1475-9276 1475-9276,10.1186/s12939-016-0356-2,,"BACKGROUND: More than 3 billion of the world's population are affected by household air pollution from relying on unprocessed solid fuels for heating and cooking. Household air pollution is harmful to human health, climate, and environment. Sustained uptake and use of cleaner cooking technologies and fuels are proposed as solutions to this problem. In this paper, we present our study protocol aimed at understanding multiple interacting feedback mechanisms involved in the dynamic behavior between social, ecological, and technological systems driving sustained use or abandonment of cleaner cooking technologies among the rural poor in India. METHODS/DESIGN: This study uses a comparative case study design to understand the dynamics of sustained use or abandonment of cleaner cooking technologies and fuels in four rural communities of Rajasthan, India. The study adopts a community based system dynamics modeling approach. We describe our approach of using community based system dynamics with rural communities to delineate the feedback mechanisms involved in the uptake and sustainment of clean cooking technologies. We develop a reference mode with communities showing the trend over time of use or abandonment of cleaner cooking technologies and fuels in these communities. Subsequently, the study develops a system dynamics model with communities to understand the complex sub-systems driving the behavior in these communities as reflected in the reference mode. We use group model building techniques to facilitate participation of relevant stakeholders in the four communities and elicit a narrative describing the feedback mechanisms underlying sustained adoption or abandonment of cleaner cooking technologies. DISCUSSION: In understanding the dynamics of feedback mechanisms in the uptake and exclusive use of cleaner cooking systems, we increase the likelihood of dissemination and implementation of efficacious interventions into everyday settings to improve the health and wellbeing of women and children most affected by household air pollution. The challenge is not confined to developing robust technical solutions to reduce household air pollution and exposure to improve respiratory health, and prevent associated diseases. The bigger challenge is to disseminate and implement cleaner cooking technologies and fuels in the context of various social, behavioral, and economic constraints faced by poor households and communities. TRIAL REGISTRATION: The Institutional Review Board of Washington University in St. Louis has exempted community based system dynamics modeling from review.",26/04/2016,26/11/2018 12:51,14/04/2020 08:34,,70,,,15,,Int J Equity Health,,,,,,,,eng,,,,,,,PMID: 27113743 PMCID: PMC4845479,,,,"Humans; Female; India; 00; Group model building; *Family Characteristics; Air Pollution, Indoor/*statistics & numerical data; Clean cooking technologies; Community based system dynamics; Community Participation/*methods/trends; Cooking/*methods; Dissemination & implementation; Equipment and Supplies/standards/supply & distribution; Household air pollution; Rural Population/trends; Sustained adoption; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5XNPD8JS,journalArticle,2016,"Dianis, Nancy L.; Wolbach, Tracy L.; Spiegelman, Maura",The NHLBI-UnitedHealth Global Health Centers of Excellence Program: Assessment of Impact of Federal Funding Through a Social Network Analysis.,Global heart,,2211-8179,10.1016/j.gheart.2015.12.006,,,2016-03,26/11/2018 12:51,14/04/2020 08:34,,145-148.e1,,1,11,,Glob Heart,,,,,,,,eng,,,,,,,PMID: 27102034 PMCID: PMC4843133,,,,"Humans; United States; *Global Health; Social Support; 00; *Federal Government; *Financing, Government; *National Heart, Lung, and Blood Institute (U.S.); *Public-Private Sector Partnerships; *Research Support as Topic; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XRB478RC,journalArticle,2016,"Bond, Raymond; Finlay, Dewar D.; Guldenring, Daniel; Breen, Cathal",Data Driven Computer Simulation to Analyse an ECG Limb Lead System Used in Connected Health Environments.,Methods of information in medicine,,2511-705X 0026-1270,10.3414/ME15-01-0120,,"BACKGROUND: Recently under the Connected Health initiative, researchers and small-medium engineering companies have developed Electrocardiogram (ECG) monitoring devices that incorporate non-standard limb electrode positions, which we have named the Central Einthoven (CE) configuration. OBJECTIVES: The main objective of this study is to compare ECG signals recorded from the CE configuration with those recorded from the recommended Mason-Likar (ML) configuration. METHODS: This study involved extracting two different sets of ECG limb leads from each patient to compare the difference in the signals. This was done using computer simulation that is driven by body surface potential maps. This simulator was developed to facilitate this experiment but it can also be used to test similar hypotheses. This study included, (a) 176 ECGs derived using the ML electrode positions and (b) the 176 corresponding ECGs derived using the CE electrode positions. The signals from these ECGs were compared using root mean square error (RMSE), Pearson product-moment correlation coefficient (r) and similarity coefficient (SC). We also investigated whether the CE configuration influences the calculated mean cardiac axis. The top 10 cases where the ECGs were significantly different between the two configurations were visually compared by an ECG interpreter. RESULTS: We found that the leads aVL, III and aVF are most affected when using the CE configuration. The absolute mean difference between the QRS axes from both configurations was 28 degrees (SD = 37 degrees ). In addition, we found that in 82% of the QRS axes calculated from the CE configuration was more rightward in comparison to the QRS axes derived from the ML configuration. Also, we found that there is an 18% chance that a misleading axis will be located in the inferior right quadrant when using the CE approach. Thus, the CE configuration can emulate right axis deviation. The clinician visually identified 6 out of 10 cases where the CE based ECG yielded clinical differences that could result in false positives. CONCLUSIONS: The CE configuration will not yield the same diagnostic accuracy for diagnosing pathologies that rely on current amplitude criteria. Conversely, rhythm lead II was not significantly affected, which supports the use of the CE approach for assessing cardiac rhythm only. Any computerised analysis of the CE based ECG will need to take these findings into consideration.",17/05/2016,26/11/2018 12:51,14/04/2020 08:34,,258-265,,3,55,,Methods Inf Med,,,,,,,,eng,,,,,,,PMID: 27096217,,,,Humans; *Computer Simulation; Algorithms; *Electrocardiography; computer simulation; 00; *Health Information Systems; *Statistics as Topic; connected health; Electrocardiogram; electrode misplacement; Electrodes; Extremities; limb lead systems; telehealth; Wireless Technology; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UD9XBE92,journalArticle,2016,"MacDougall-Davis, S. R.; Kettley, L.; Cook, T. M.",The 'go-between' study: a simulation study comparing the 'Traffic Lights' and 'SBAR' tools as a means of communication between anaesthetic staff.,Anaesthesia,,1365-2044 0003-2409,10.1111/anae.13464,,"Communicating non-urgent, urgent and frank emergency requests for assistance between anaesthetists in theatre often requires a 'go-between' - frequently a non-anaesthetic healthcare professional - to transmit information. We compared the currently recommended situation, background, assessment, recommendation (SBAR) tool with a newly devised Traffic Lights tool ('red alert', 'amber assist' and 'green query') in a simulation study to assess communication quality using 12 validated clinical scenarios of varying urgency. Compared to SBAR, Traffic Lights was used more consistently ('very clear' or 'clear' Traffic Lights 94% vs SBAR 69%); transferred information better (two or three pieces of information correctly transferred Traffic Lights 85%, SBAR 44%; and was judged to lead to greater clarity (all p < 0.0001). Message delivery time was significantly reduced (Traffic Lights 20.5 s vs SBAR 45.5 s, median (95% CI) difference 25 (19-30) s, p < 0.001). Users rated the Traffic Lights system as significantly more useful than SBAR, with 96% of participants preferring the Traffic Lights tool. Results were independent of go-between training. We recommend the adoption of this communication tool as standard practice for anaesthetic teams.",2016-07,26/11/2018 12:51,14/04/2020 08:34,,764-772,,7,71,,Anaesthesia,,,,,,,,eng,(c) 2016 The Association of Anaesthetists of Great Britain and Ireland.,,,,,,PMID: 27080525,,,,"Humans; *Communication; *Patient Care Team; Manikins; *Audiovisual Aids; 00; *patient safety; *communication; *emergency; *human factors; *interdisciplinary communication; *Medical Staff, Hospital; *Operating Rooms; Anesthesiology/*methods; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QVX4UF6K,journalArticle,2016,"Hardoff, Daniel; Gefen, Assaf; Sagi, Doron; Ziv, Amitai",Dignity in adolescent health care: a simulation-based training programme.,Medical education,,1365-2923 0308-0110,10.1111/medu.13024,,,2016-05,26/11/2018 12:51,14/04/2020 08:34,,570-571,,5,50,,Med Educ,,,,,,,,eng,,,,,,,PMID: 27072455,,,,Humans; Physician-Patient Relations; *Patient Simulation; Curriculum; Adolescent; 00; Parents; *Personhood; Adolescent Medicine/*education/standards; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WGMVGBJY,journalArticle,2016,"Kirkbakk-Fjaer, Kari; Hedelin, Birgitta; Moen, Oyfrid Larsen",Undergraduate Nursing Students' Evaluation of the Debriefing Phase in Mental Health Nursing Simulation.,Issues in mental health nursing,,1096-4673 0161-2840,10.3109/01612840.2015.1136716,,"The debriefing phase in mental health nursing simulation promotes a reflexive learning process with the opportunity to develop metacognitive and nontechnical skills. The aim of this quantitative study was to describe undergraduate nursing students' evaluation of their experience during the debriefing phase following high fidelity human simulation (HFHS). Data was collected using the ""Debriefing Experience Scale"" and analysed with descriptive and comparative tests. The debriefing phase was evaluated as very good. Background data and group size revealed few significant differences. Students with little clinical praxis evaluated having time to acknowledge feelings as important. Differences between groups revealed that groups should consist of up to eighteen students.",2016-05,26/11/2018 12:51,14/04/2020 08:34,,360-366,,5,37,,Issues Ment Health Nurs,,,,,,,,eng,,,,,,,PMID: 27050663,,,,"Humans; Adult; Female; Male; Middle Aged; Young Adult; Psychiatric Nursing/*education; *Formative Feedback; *Education, Nursing, Baccalaureate; Age Factors; 00; Students, Nursing; *High Fidelity Simulation Training; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EMW3NMQ6,journalArticle,2016,"Huang, Jin-Hui; Liu, Wen-Chu; Zeng, Guang-Ming; Li, Fei; Huang, Xiao-Long; Gu, Yan-Ling; Shi, Li-Xiu; Shi, Ya-Hui; Wan, Jia",An exploration of spatial human health risk assessment of soil toxic metals under different land uses using sequential indicator simulation.,Ecotoxicology and environmental safety,,1090-2414 0147-6513,10.1016/j.ecoenv.2016.03.029,,"A modified method was proposed which integrates the spatial patterns of toxic metals simulated by sequential indicator simulation, different exposure models and local current land uses extracted by remote-sensing software into a dose-response model for human health risk assessment of toxic metals. A total of 156 soil samples with a various land uses containing farm land (F1-F25), forest land (W1-W12) and residential land (U1-U15) were collected in a grid pattern throughout Xiandao District (XDD), Hunan Province, China. The total Cr and Pb in topsoil were analyzed. Compared with Hunan soil background values, the elevated concentrations of Cr were mainly located in the east of XDD, and the elevated concentrations of Pb were scattered in the areas around F1, F6, F8, F13, F14, U5, U14, W2 and W11. For non-carcinogenic effects, the hazard index (HI) of Cr and Pb overall the XDD did not exceed the accepted level to adults. While to children, Cr and Pb exhibited HI higher than the accepted level around some areas. The assessment results indicated Cr and Pb should be regarded as the priority pollutants of concern in XDD. The first priority areas of concern were identified in region A with a high probability (>0.95) of risk in excess of the accepted level for Cr and Pb. The areas with probability of risk between 0.85 and 0.95 in region A were identified to be the secondary priority areas for Cr and Pb. The modified method was proved useful due to its improvement on previous studies and calculating a more realistic human health risk, thus reducing the probability of excessive environmental management.",2016-07,26/11/2018 12:51,14/04/2020 08:34,,199-209,,,129,,Ecotoxicol Environ Saf,,,,,,,,eng,Copyright (c) 2016 Elsevier Inc. All rights reserved.,,,,,,PMID: 27045920,,,,"Humans; Adult; Child; Risk Assessment; Models, Theoretical; Dose-Response Relationship, Drug; China; 00; Soil; Chromium/analysis/toxicity; Environmental Exposure/*analysis; Health risk assessment; Land use; Lead/analysis/toxicity; Sequential indicator simulation; Soil Pollutants/*analysis/toxicity; Soil/*chemistry; Toxic metals; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VHVVEM3J,journalArticle,2016,"Wong, Ambrose Hon-Wai; Gang, Maureen; Szyld, Demian; Mahoney, Heather","Making an ""Attitude Adjustment"": Using a Simulation-Enhanced Interprofessional Education Strategy to Improve Attitudes Toward Teamwork and Communication.",Simulation in healthcare : journal of the Society for Simulation in Healthcare,,1559-713X 1559-2332,10.1097/SIH.0000000000000133,,"INTRODUCTION: Health care providers must effectively function in highly skilled teams in a collaborative manner, but there are few interprofessional training strategies in place. Interprofessional education (IPE) using simulation technology has gained popularity to address this need because of its inherent ability to impact learners' cognitive frames and promote peer-to-peer dialog. Provider attitudes toward teamwork have been directly linked to the quality of patient care. Investigators implemented a simulation-enhanced IPE intervention to improve staff attitudes toward teamwork and interprofessional communication in the emergency department setting. METHODS: The 3-hour course consisted of a didactic session highlighting teamwork and communication strategies, 2 simulation scenarios on septic shock and cardiac arrest, and structured debriefing directed at impacting participant attitudes to teamwork and communication. This was a survey-based observational study. We used the TeamSTEPPS Teamwork Attitudes Questionnaire immediately before and after the session as a measurement of attitude change as well as the Hospital Survey on Patient Safety Culture before the session and 1 year after the intervention for program impact at the behavior level. RESULTS: Seventy-two emergency department nurses and resident physicians participated in the course from July to September 2012. Of the 5 constructs in TeamSTEPPS Teamwork Attitudes Questionnaire, 4 had a significant improvement in scores-6.4%, 2.8%, 4.0%, and 4.0% for team structure, leadership, situation monitoring, and mutual support, respectively (P < 0.0001, P = 0.029, P = 0.014, and P = 0.003, respectively). For Hospital Survey on Patient Safety Culture, 3 of 6 composites directly related to teamwork and communication showed a significant improvement-20.6%, 20.5%, and 23.9%, for frequency of event reporting, teamwork within hospital units, and hospital handoffs and transitions, respectively (P = 0.028, P = 0.035, and P = 0.024, respectively). CONCLUSIONS: A simulation-enhanced IPE curriculum was successful in improving participant attitudes toward teamwork and components of patient safety culture related to teamwork and communication.",2016-04,26/11/2018 12:51,14/04/2020 08:35,,117-125,,2,11,,Simul Healthc,,,,,,,,eng,,,,,,,PMID: 27043097,,,,"Humans; Patient Care Team/organization & administration; Patient Safety; Curriculum; Emergency Service, Hospital/*organization & administration; Communication; *Attitude of Health Personnel; *Interprofessional Relations; Cooperative Behavior; Organizational Culture; 00; Nursing Staff, Hospital/*psychology; Simulation Training/*organization & administration; Internship and Residency/*organization & administration; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 467HGYAR,journalArticle,2016,"Phrampus, Paul E.; O'Donnell, John M.; Farkas, Deborah; Abernethy, Denise; Brownlee, Katherine; Dongilli, Thomas; Martin, Susan","Rapid Development and Deployment of Ebola Readiness Training Across an Academic Health System: The Critical Role of Simulation Education, Consulting, and Systems Integration.",Simulation in healthcare : journal of the Society for Simulation in Healthcare,,1559-713X 1559-2332,10.1097/SIH.0000000000000137,,"STATEMENT: In this article, we describe an Ebola preparedness initiative with implementation across an academic health system. Key stakeholder centers of various disciplines and clinical experts collaborated in the development and design. Subject matter experts in the areas of Centers for Disease Control and Prevention and World Health Organization protocols for personal protective equipment donning and doffing conducted initial train-the-trainer sessions for program instructors. These trainers represented a cross-section of key clinical responders and environmental services. Through a parallel development process, a blended learning curriculum consisting of online modules followed by on-site training sessions was developed and implemented in both the simulation laboratory and the actual clinical care spaces in preparation for a Department of Health inspection. Lessons learned included identification of the need for iterative refinement based on instructor and trainee feedback, the lack of tolerance of practitioners in wearing full-body personal protective equipment for extended periods, and the ability of a large system to mount a rapid response to a potential public health threat through leveraging of expertise of its Simulation Program, Center for Quality, Safety and Innovation as well as a wide variety of clinical departments.",2016-04,26/11/2018 12:51,14/04/2020 08:35,,82-88,,2,11,,Simul Healthc,,,,,,,,eng,,,,,,,PMID: 27043092,,,,"Humans; Program Evaluation; United States; Curriculum; Formative Feedback; Health Personnel/*education; Disaster Planning/*organization & administration; Internet; 00; Simulation Training/*organization & administration; Hemorrhagic Fever, Ebola/*prevention & control/therapy/transmission; Infection Control/organization & administration; Personal Protective Equipment/utilization; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JCIY4CE7,journalArticle,2016,"Gale, Thomas C. E.; Chatterjee, Arunangsu; Mellor, Nicholas E.; Allan, Richard J.",Health Worker Focused Distributed Simulation for Improving Capability of Health Systems in Liberia.,Simulation in healthcare : journal of the Society for Simulation in Healthcare,,1559-713X 1559-2332,10.1097/SIH.0000000000000156,,"INTRODUCTION: The main goal of this study was to produce an adaptable learning platform using virtual learning and distributed simulation, which can be used to train health care workers, across a wide geographical area, key safety messages regarding infection prevention control (IPC). METHODS: A situationally responsive agile methodology, Scrum, was used to develop a distributed simulation module using short 1-week iterations and continuous synchronous plus asynchronous communication including end users and IPC experts. The module contained content related to standard IPC precautions (including handwashing techniques) and was structured into 3 distinct sections related to donning, doffing, and hazard perception training. OUTCOME: Using Scrum methodology, we were able to link concepts applied to best practices in simulation-based medical education (deliberate practice, continuous feedback, self-assessment, and exposure to uncommon events), pedagogic principles related to adult learning (clear goals, contextual awareness, motivational features), and key learning outcomes regarding IPC, as a rapid response initiative to the Ebola outbreak in West Africa. Gamification approach has been used to map learning mechanics to enhance user engagement. CONCLUSIONS: The developed IPC module demonstrates how high-frequency, low-fidelity simulations can be rapidly designed using scrum-based agile methodology. Analytics incorporated into the tool can help demonstrate improved confidence and competence of health care workers who are treating patients within an Ebola virus disease outbreak region. These concepts could be used in a range of evolving disasters where rapid development and communication of key learning messages are required.",2016-04,26/11/2018 12:51,14/04/2020 08:34,,75-81,,2,11,,Simul Healthc,,,,,,,,eng,,,,,,,PMID: 27043091,,,,"Humans; Quality of Health Care; Clinical Competence; Formative Feedback; Simulation Training/*methods; Health Personnel/*education; User-Computer Interface; Communicable Disease Control/*organization & administration; 00; Hemorrhagic Fever, Ebola/*prevention & control/therapy/transmission; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, D34323KU,journalArticle,2016,"Ratz, David; Hofer, Timothy; Flanders, Scott A.; Saint, Sanjay; Chopra, Vineet",Limiting the Number of Lumens in Peripherally Inserted Central Catheters to Improve Outcomes and Reduce Cost: A Simulation Study.,Infection control and hospital epidemiology,,1559-6834 0899-823X,10.1017/ice.2016.55,,"BACKGROUND The number of peripherally inserted central catheter (PICC) lumens is associated with thrombotic and infectious complications. Because multilumen PICCs are not necessary in all patients, policies that limit their use may improve safety and cost. OBJECTIVE To design a simulation-based analysis to estimate outcomes and cost associated with a policy that encourages single-lumen PICC use. METHODS Model inputs, including risk of complications and costs associated with single- and multilumen PICCs, were obtained from available literature and a multihospital collaborative quality improvement project. Cost savings and reduction in central line-associated bloodstream infection and deep vein thrombosis events from institution of a single-lumen PICC default policy were reported. RESULTS According to our model, a hospital that places 1,000 PICCs per year (25% of which are single-lumen and 75% multilumen) experiences annual",2016-07,26/11/2018 12:51,14/04/2020 08:35,,811-817,,7,37,,Infect Control Hosp Epidemiol,,,,,,,,eng,,,,,,,PMID: 27033138,,,,"Humans; 00; Catheter-Related Infections/economics/epidemiology/prevention & control; Catheterization, Peripheral/*adverse effects/economics/instrumentation/methods; Central Venous Catheters/*adverse effects/economics; Cost Savings/*methods; Cross Infection/epidemiology/prevention & control; Hospital Costs/statistics & numerical data; Venous Thrombosis/economics/epidemiology/prevention & control; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, P4DZXE9U,journalArticle,2016,"Fossen, Peggy; Stoeckel, Pamella Rae",Nursing Students' Perceptions of a Hearing Voices Simulation and Role-Play: Preparation for Mental Health Clinical Practice.,The Journal of nursing education,,1938-2421 0148-4834,10.3928/01484834-20160316-04,,"BACKGROUND: Baccalaureate nursing students experience anxiety before working with patients with mental illness who hear voices. A hearing voices simulation and role-play was proposed as an approach to preparing students for clinical practice. METHOD: A qualitative interpretive phenomenological method was used to determine students' perceptions of the simulation experience before their first mental health clinical rotation. RESULTS: Through the experience of the Walking in the Shoes of Patients activity, written student surveys revealed themes of Reflecting on Past Experiences, Developing Changed Perspectives, and Different Approaches to Care. CONCLUSION: The hearing voices simulation provided students with a greater understanding of the experience of hearing voices, and the role-play helped students to gain personal insight into patients' behaviors and practice skills learned in preparation for their first mental health clinical experience.",2016-04,26/11/2018 12:51,14/04/2020 08:34,,203-208,,4,55,,J Nurs Educ,,,,,,,,eng,"Copyright 2016, SLACK Incorporated.",,,,,,PMID: 27023889,,,,"Humans; Surveys and Questionnaires; Adult; Female; Male; Nursing Education Research; Young Adult; Qualitative Research; Education, Nursing, Baccalaureate; Psychiatric Nursing/*education; 00; *Acoustic Stimulation; *Role Playing; Anxiety; Hallucinations/nursing/*psychology; Mental Disorders/nursing; Students, Nursing/*psychology/statistics & numerical data; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Y8FWBT34,journalArticle,2017,"Yildirim, Ahmet; Kiraz, Hasan A.; Agaoglu, Ibrahim; Akdur, Okhan","Comparison of Macintosh, McCoy and C-MAC D-Blade video laryngoscope intubation by prehospital emergency health workers: a simulation study.",Internal and emergency medicine,,1970-9366 1828-0447,10.1007/s11739-016-1437-3,,"The aim of the this study is to evaluate the intubation success rates of emergency medical technicians using a Macintosh laryngoscope (ML), McCoy laryngoscope (MCL), and C MAC D-Blade (CMDB) video laryngoscope on manikin models with immobilized cervical spines. This randomized crossover study included 40 EMTs with at least 2 years' active service in ambulances. All participating technicians completed intubations in three scenarios-a normal airway model, a rigid cervical collar model, and a manual in-line cervical stabilization model-with three different laryngoscopes. The scenario and laryngoscope model were determined randomly. We recorded the scenario, laryngoscope method, intubation time in seconds, tooth pressure, and intubation on a previously prepared study form. We performed Friedman tests to determine whether there is a significant change in the intubation success rate, duration of tracheal intubation, tooth pressure, and visual analog scale scores due to violations of parametric test assumptions. We performed the Wilcoxon test to determine the significance of pairwise differences for multiple comparisons. An overall 5 % type I error level was used to infer statistical significance. We considered a p value of less than 0.05 statistically significant. The CMDB and MCL success rates were significantly higher than the ML rates in all scenario models (p < 0.05). The CMDB intubation duration was significantly shorter when compared with ML and MCL in all models. CMDB and MCL may provide an easier, faster intubation by prehospital emergency health care workers in patients with immobilized cervical spines.",2017-02,26/11/2018 12:51,14/04/2020 08:35,,91-97,,1,12,,Intern Emerg Med,,,,,,,,eng,,,,,,,PMID: 27001885,,,,"Humans; Adult; Female; Male; Manikins; 00; Manikin; Emergency Medical Services/*manpower/statistics & numerical data; Equipment Design/standards; Intubation; Intubation, Intratracheal/*instrumentation/methods/statistics & numerical data; Laryngoscope; Laryngoscopes/*standards/statistics & numerical data; Prehospital; Simulation Training/methods/statistics & numerical data; Video; Video-Assisted Surgery/*methods/standards/statistics & numerical data; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, X73YIGA6,journalArticle,2017,"Wang, Han-I.; Smith, Alexandra; Aas, Eline; Roman, Eve; Crouch, Simon; Burton, Cathy; Patmore, Russell",Treatment cost and life expectancy of diffuse large B-cell lymphoma (DLBCL): a discrete event simulation model on a UK population-based observational cohort.,The European journal of health economics : HEPAC : health economics in prevention and care,,1618-7601 1618-7598,10.1007/s10198-016-0775-4,,"BACKGROUND: Diffuse large B-cell lymphoma (DLBCL) is the commonest non-Hodgkin lymphoma. Previous studies examining the cost of treating DLBCL have generally focused on a specific first-line therapy alone; meaning that their findings can neither be extrapolated to the general patient population nor to other points along the treatment pathway. Based on empirical data from a representative population-based patient cohort, the objective of this study was to develop a simulation model that could predict costs and life expectancy of treating DLBCL. METHODS: All patients newly diagnosed with DLBCL in the UK's population-based Haematological Malignancy Research Network ( www.hmrn.org ) in 2007 were followed until 2013 (n = 271). Mapped treatment pathways, alongside cost information derived from the National Tariff 2013/14, were incorporated into a patient-level simulation model in order to reflect the heterogeneities of patient characteristics and treatment options. The NHS and social services perspective was adopted, and all outcomes were discounted at 3.5 % per annum. RESULTS: Overall, the expected total medical costs were pound22,122 for those treated with curative intent, and pound2930 for those managed palliatively. For curative chemotherapy, the predicted medical costs were pound14,966, pound23,449 and pound7376 for first-, second- and third-line treatments, respectively. The estimated annual cost for treating DLBCL across the UK was around pound88-92 million. CONCLUSIONS: This is the first cost modelling study using empirical data to provide 'real world' evidence throughout the DLBCL treatment pathway. Future application of the model could include evaluation of new technologies/treatments to support healthcare decision makers, especially in the era of personalised medicine.",2017-03,26/11/2018 12:51,14/04/2020 08:35,,255-267,,2,18,,Eur J Health Econ,,,,,,,,eng,,,,,,,PMID: 26969332 PMCID: PMC5313581,,,,"Humans; Adult; Female; Male; Middle Aged; Aged; Decision Support Techniques; Aged, 80 and over; Time Factors; United Kingdom; Models, Econometric; Costs and Cost Analysis; State Medicine; Cost; *Life Expectancy; Discrete event simulation; 00; Diffuse large B-cell lymphoma; DLBCL; Lymphoma, Large B-Cell, Diffuse/*economics/*therapy; Palliative Care/economics; Patient-level simulation; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CPVJEF3F,journalArticle,2016,"Caro, J. Jaime; Moller, Jorgen",Advantages and disadvantages of discrete-event simulation for health economic analyses.,Expert review of pharmacoeconomics & outcomes research,,1744-8379 1473-7167,10.1586/14737167.2016.1165608,,,2016-06,26/11/2018 12:51,14/04/2020 08:34,,327-329,,3,16,,Expert Rev Pharmacoecon Outcomes Res,,,,,,,,eng,,,,,,,PMID: 26967022,,,,"Humans; *Models, Economic; Decision Making; Computer Simulation; *Simulation; 1; Technology Assessment, Biomedical/*methods; *modeling; *discrete event; *health economic analyses; *health technology assessment; Biomedical Technology/*economics; ******To read; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VWWIC3RM,journalArticle,2016,"Dabanovic, Vera; Kostic, Marina; Jankovic, Slobodan",Cost effectiveness comparison of dutasteride and finasteride in patients with benign prostatic hyperplasia--The Markov model based on data from Montenegro.,Vojnosanitetski pregled,,0042-8450 0042-8450,,,"BACKGROUND/AIM: Benign prostatic hyperplasia (BPH) is one of the most common disease among males aging 50 years and more. The rise of the prevalence of BPH is related to aging, and since duration of life time period has the tendency of rising the prevalence of BPH will rise as costs of BPH treatment will and its influence on health economic budget. Dutasteride is a new drug similar to finasteride, inhibits enzyme testosterone 5-alpha reductase, diminish symptoms of BPH, reduce risk of the complications and increases quality of life in patients with BPH. But, the use of dutasteride is limited by its high costs. The aim of this study was to compare cost effectiveness of dutasteride and finasteride from the perspective of a purchaser of health care service (Republic Institute for Health Insuranse, Montenegro). METHODS: We constructed a Markov model to compare cost effectivenss of dutasteride and finasteride using data from the available pharmacoeconomic literature and data about socioeconomic sphere actual in Montenegro. A time horizon was estimated to be 20 years, with the duration of 1 year per one cycle. The discount rate was 3%. We performed Monte Carlo simulation for virtual cohort of 1,000 patients with BPH. RESULTS: The total costs for one year treatment of BPH with dutasteride were estimated to be 6,458.00 euro which was higher comparing with finasteride which were 6,088.56 euro. The gain in quality adjusted life years (QALY) were higher with dutasteride (11.97 QALY) than with finasteride (11.19 QALY). The results of our study indicate that treating BPH with dutasteride comparing to finasteride is a cost effective option since the value of incremental cost-effectiveness ratio (ICER) is 1,245.68 euro/QALY which is below estimated threshold (1,350.00 euro per one gained year of life). CONCLUSION: Dutasteride is a cost effective option for treating BPH comparing to finasteride. The results of this study provide new information for health care decision makers about treatment of BPH in socioeconomic environment which is actual both in Montenegro and other countries with a recent history of socioeconomic transition.",2016-01,26/11/2018 12:51,14/04/2020 08:34,,26-33,,1,73,,Vojnosanit Pregl,,,,,,,,eng,,,,,,,PMID: 26964381,,,,Humans; Budgets; Treatment Outcome; Male; Aged; Quality of Life; *Markov Chains; *Cost-Benefit Analysis/economics; 5-alpha Reductase Inhibitors/*economics/therapeutic use; Aging; Dutasteride/*economics/therapeutic use; Finasteride/*economics/therapeutic use; Montenegro; Prostatic Hyperplasia/drug therapy/*economics; 00; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Y74Y62HF,journalArticle,2016,"Samuelson, Eric M.; Odum, Susan M.; Fleischli, James E.",The Cost-Effectiveness of Using Platelet-Rich Plasma During Rotator Cuff Repair: A Markov Model Analysis.,Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association,,1526-3231 0749-8063,10.1016/j.arthro.2015.12.018,,"PURPOSE: To perform a cost-utility analysis to determine if the use of platelet-rich plasma (PRP) products during arthroscopic rotator cuff repair (RCR) is cost-effective. METHODS: A cost-utility analysis was conducted using a Markov decision model. Model inputs including health utility values, retear rates, and transition probabilities were derived from the best evidence available in the literature regarding full-thickness rotator cuff tears and their repair, as well as the augmentation of their repair with PRP. Costs were determined by examining the typical patient undergoing treatment for a full-thickness rotator cuff tear in a private orthopaedic clinic and outpatient surgery center. RESULTS: The cost per quality-adjusted life-year ($/QALY) of RCR with and without PRP was $6,775/QALY and $6,612/QALY, respectively. In our base case, the use of PRP to augment RCR was not cost-effective because it had exactly the same ""effectiveness"" as RCR without PRP augmentation while being associated with a higher cost (additional $750). Sensitivity analysis showed that to achieve a willingness-to-pay threshold of $50,000/QALY, the addition of PRP would need to be associated with a 9.1% reduction in retear rates. If the cost of PRP were increased to $1,000, the retear rate would need to be reduced by 12.1% to reach this same threshold. This compared with a necessary reduction of only 6.1% if the additional cost of PRP was $500. CONCLUSIONS: This cost-utility analysis shows that, currently, the use of PRP to augment RCR is not cost-effective. Sensitivity analysis showed that PRP-augmented repairs would have to show a reduced retear rate of at least 9.1% before the additional cost would be considered cost-effective. LEVEL OF EVIDENCE: Level III, analysis of Level I, II, and III studies.",2016-07,26/11/2018 12:51,14/04/2020 08:35,,1237-1244,,7,32,,Arthroscopy,,,,,,,,eng,Copyright (c) 2016 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.,,,,,,PMID: 26927681,,,,Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; *Markov Chains; *Arthroscopy; *Platelet-Rich Plasma; Rotator Cuff Injuries/*surgery; 00; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WE7R2DZK,journalArticle,2016,"Guerin, Patrice; Bourguignon, Sandrine; Jamet, Nicolas; Marque, Sebastien",MitraClip therapy in mitral regurgitation: a Markov model for the cost-effectiveness of a new therapeutic option.,Journal of medical economics,,1941-837X 1369-6998,10.3111/13696998.2016.1157484,,"Introduction Mitral regurgitation is a heart condition resulting from blood flowing from the left ventricle towards the left atrium, increasing the risk of heart failure and mortality. While surgery can greatly reduce these risks, some patients are not eligible, resulting in medication being their only therapeutic alternative. The MitraClip (Abbot Vascular) is a medical device that is percutaneously implanted and designed to eliminate leaking of the mitral valve. Methods The efficacy of the MitraClip strategy vs medical management was assessed using a 4-state Markov model based on the mitral regurgitation grade (mitral regurgitation grade 0, I/II, and III/IV, and death). At each 1-month cycle, patients were or were not hospitalized. The model analyzed a fictional population of 1000 patients over a 5-year period from a national Health Insurance perspective. The primary end-point was the number of deaths avoided. Data from the EVEREST II High Risk Study patients were used along with a literature review. Results At 5 years, among the 1000 patients, 276 deaths were found to be avoidable with the MitraClip strategy. The incremental cost-effectiveness ratio (ICER) was euro93,363 per death avoided. The annual ICER was calculated to take into consideration excess costs resulting from the MitraClip over the first year (euro29,984 vs euro8557 for the reference strategy) and the reduction of costs in following years (euro3122 for MitraClip vs euro8557 for reference strategy). Thus, the mean ICER was calculated to be euro20,720 per death avoided. Conclusion The MitraClip is a novel alternative therapy for mitral insufficiency in patients ineligible for surgery that may offer a medico-economic advantage.",2016-07,26/11/2018 12:51,14/04/2020 08:34,,696-701,,7,19,,J Med Econ,,,,,,,,eng,,,,,,,PMID: 26909557,,,,"Humans; Cost-Benefit Analysis; Female; Male; Markov Chains; Models, Econometric; Cost-effectiveness; Heart failure; Heart Failure/economics/prevention & control; Markov Model; MitraClip; Mitral regurgitation; Mitral Valve Insufficiency/*economics/mortality/*surgery; 00; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, T7YZIFVN,journalArticle,2016,"Zollner, York Francis; Ziegler, Ralph; Stuve, Magnus; Krumreich, Julia; Schauf, Marion",Event and Cost Offsets of Switching 20% of the Type 1 Diabetes Population in Germany From Multiple Daily Injections to Continuous Subcutaneous Insulin Infusion: A 4-Year Simulation Model.,Journal of diabetes science and technology,,1932-2968 1932-2968,10.1177/1932296816633720,,"BACKGROUND: Most patients with type 1 diabetes (T1D) administer insulin by multiple daily injections (MDI). However, continuous subcutaneous insulin infusion (CSII) therapy has been shown to improve glycemic control compared with MDI. OBJECTIVE: The objective was to determine the key medical event and cost offsets generated over a 4-year period by introducing CSII to T1D patients who have inadequately controlled glucose metabolism on MDI in Germany. METHODS: A decision-analytic budget impact model, simulating a treatment switch scenario, was developed. In the base case, all T1D patients received MDI, while in the switch scenario, 20% of the eligible T1D population, randomly selected, moved to CSII. The model focused on 2 medical endpoints and their corresponding cost offsets: severe hypoglycemic events requiring hospitalization (SHEH) and complication-borne diabetic events (CDEs) avoided. Event rates and costs were taken from the literature and official sources, adopting a health insurance perspective. RESULTS: Compared with the base case, treating 20% of patients with CSII in the switch scenario resulted in 47 864 fewer SHEH and 5543 fewer CDEs. This led to total cost offsets of euro183 085 281 within the 4-year time horizon. Of these, 92% were driven by avoided SHEH. Compared to an expected budget impact (cost increase) of 83%, only treatment costs considered, the total impact of the switch scenario amounted merely to a 24.5% increase in costs (reduction by 58.5% points; a factor of 3.4). CONCLUSION: The use of CSII resulted in fewer SHEH and CDEs compared to MDI. The incurred CSII implementation costs are hence offset to a substantial degree by cost savings in complication treatment.",2016-09,26/11/2018 12:51,14/04/2020 08:35,,1142-1148,,5,10,,J Diabetes Sci Technol,,,,,,,,eng,(c) 2016 Diabetes Technology Society.,,,,,,PMID: 26902790 PMCID: PMC5032942,,,,"Humans; Cost-Benefit Analysis; Diabetes Complications/economics; Models, Economic; 1; *budget impact; *complication-borne diabetic events; *continuous subcutaneous insulin infusion; *German costs data; *glucose monitoring; *severe hypoglycemic events; *type 1 diabetes; Diabetes Mellitus, Type 1/*drug therapy; Hypoglycemic Agents/*administration & dosage; Infusions, Subcutaneous/economics; Insulin Infusion Systems/*economics; Insulin/*administration & dosage; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WY9K8XBW,journalArticle,2016,"Johnson, Owen A.; Hall, Peter S.; Hulme, Claire",NETIMIS: Dynamic Simulation of Health Economics Outcomes Using Big Data.,PharmacoEconomics,,1179-2027 1170-7690,10.1007/s40273-016-0384-1,,"Many healthcare organizations are now making good use of electronic health record (EHR) systems to record clinical information about their patients and the details of their healthcare. Electronic data in EHRs is generated by people engaged in complex processes within complex environments, and their human input, albeit shaped by computer systems, is compromised by many human factors. These data are potentially valuable to health economists and outcomes researchers but are sufficiently large and complex enough to be considered part of the new frontier of 'big data'. This paper describes emerging methods that draw together data mining, process modelling, activity-based costing and dynamic simulation models. Our research infrastructure includes safe links to Leeds hospital's EHRs with 3 million secondary and tertiary care patients. We created a multidisciplinary team of health economists, clinical specialists, and data and computer scientists, and developed a dynamic simulation tool called NETIMIS (Network Tools for Intervention Modelling with Intelligent Simulation; http://www.netimis.com ) suitable for visualization of both human-designed and data-mined processes which can then be used for 'what-if' analysis by stakeholders interested in costing, designing and evaluating healthcare interventions. We present two examples of model development to illustrate how dynamic simulation can be informed by big data from an EHR. We found the tool provided a focal point for multidisciplinary team work to help them iteratively and collaboratively 'deep dive' into big data.",2016-02,26/11/2018 12:51,14/04/2020 08:34,,107-114,,2,34,,Pharmacoeconomics,,,,,,,,eng,,,,,,,PMID: 26879667,,,,"Humans; *Computer Simulation; Models, Theoretical; System dynamics; Interdisciplinary Communication; 1; *Economics, Medical; Data Mining/methods; Electronic Health Records/*statistics & numerical data; Neural Networks (Computer); Outcome Assessment (Health Care)/methods; 220",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JX4QUDIP,journalArticle,2016,"Cui, Ying; Chen, Wen; Chi, Jinfeng; Wang, Lei",Differential expression network analysis for diabetes mellitus type 2 based on expressed level of islet cells.,Annales d'endocrinologie,,2213-3941 0003-4266,10.1016/j.ando.2015.11.002,,"OBJECTIVE: Diabetes mellitus type 2 (T2DM) is a metabolic disease that has become a pressing issue, with potential adverse impact on mental health. We aimed to explore the potential molecular mechanism of T2DM. MATERIAL AND METHODS: GSE38642 microarray data downloaded from gene expression omnibus was used to identify the differentially expressed genes (DEGs). Profiling of complex functionality (ProfCom) was used to analyze the complex function and mine T2DM signature genes. Finally, the differential expression network (DEN) was constructed. RESULTS: We identified 147 DEGs including 59 up- and 88 down-regulated genes. With increasing of degree, the specificity of functional description of DEGs was higher. GO term of ""integral to membrane and immune response (not receptor activity) not regulation of immune response"" in degree 4 was enriched by 6 DEGs, while the GO term of ""immune response"" in degree 1 was enriched by 12 DEGs. Two complex functions of integral to membrane an immune response and response to glucose stimulus were enriched by 11 T2DM signature genes including ARG2, GLP1R, PFKFB2, PTPRN, ACSL5, CCR7, IL2RA, IL7R, IL1R2, IL1RL1 and CHST4. Finally, DEN including 11 signature genes and 491 edges was obtained. CONCLUSION: The identified DEGs especially 11 signature genes such as PTPRN, GLP1R, CCR7 and IL2RA may play important roles in the pathogenesis of T2DM.",2016-02,26/11/2018 12:51,14/04/2020 08:34,,22-29,,1,77,,Ann Endocrinol (Paris),,,,,,,,eng,Copyright (c) 2015 Elsevier Masson SAS. All rights reserved.,,,,,,PMID: 26874994,,,,"Humans; 00; *Gene Expression Regulation; Diabete de type 2; Diabetes mellitus type 2; Diabetes Mellitus, Type 2/*genetics; Differential expression network; Gene Expression Profiling; Islets of Langerhans/*metabolism; Profilage des fonctionnalites complexes; Profiling of complex functionality; Reseau d'expression differentielle; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QYK49R5W,journalArticle,2017,"Wong, Lai Yin; Toh, Matthias Paul Han Sim; Tham, Linus Wai Chung",Projection of prediabetes and diabetes population size in Singapore using a dynamic Markov model.,Journal of diabetes,,1753-0407 1753-0407,10.1111/1753-0407.12384,,"BACKGROUND: The aim of the present study was to forecast the prevalence and number of adult Singapore residents with prediabetes and diabetes in 2035. METHODS: A dynamic Markov model with nine mutually exclusive states was developed based on the clinical course of diabetes using time-dependent rates and probabilities. A 1-year cycle over a 25-year time horizon from 2010 to 2035 was used in the model. With publicly available data and a chronic disease register, the model forecast annual disease burden by simulating transition of cohorts across different health states using prevalence rates, incidence rates, mortality rates, disease transition, disease detection, and complication rates. An aging index was used in the model in anticipation of population aging to minimize risks of underestimating disease burden. RESULTS: From 2010 to 2035, the number of Singapore residents with prediabetes and diabetes is projected to more than double, from 434 685 to 903 596 and from 373 104 to 823 802, respectively. The prevalence of prediabetes and diabetes will rise steadily from 15.5 % to 24.9 % and from 13.3 % to 22.7 %, respectively. By 2035, a further estimate of 733 174 and 100 250 patients with prediabetes and uncomplicated diabetes, respectively, will remain undiagnosed. The prevalence of detected and undetected complications is forecast to rise from 60.0 % in 2010 to 70.2 % by 2035. CONCLUSION: By 2035, the prevalence of prediabetes and diabetes among Singapore residents aged 21+ years is expected to be one in four and one in five, respectively. There is an impetus to adopt more aggressive interventions to contain disease progression.",2017-01,26/11/2018 12:51,14/04/2020 08:34,,65-75,,1,9,,J Diabetes,,,,,,,,eng,"(c) 2016 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and John Wiley & Sons Australia, Ltd.",,,,,,PMID: 26849033,,,,"Humans; Adult; Female; Male; Young Adult; *Markov Chains; Incidence; *Models, Theoretical; Prevalence; Markov model; diabetes; 1; prediabetes; Diabetes Mellitus/*epidemiology/mortality; forecast; Prediabetic State/*epidemiology/mortality; Singapore/epidemiology; 210",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NGSLPFVM,journalArticle,2016,"Cheng, Adam; Morse, Kate J.; Rudolph, Jenny; Arab, Abeer A.; Runnacles, Jane; Eppich, Walter",Learner-Centered Debriefing for Health Care Simulation Education: Lessons for Faculty Development.,Simulation in healthcare : journal of the Society for Simulation in Healthcare,,1559-713X 1559-2332,10.1097/SIH.0000000000000136,,"STATEMENT: Better debriefing practices may enhance the impact of simulation-based education. Emerging literature suggests that learner-centered debriefing may be effective in helping instructors identify and address learner needs while building learner's engagement and sense of responsibility for learning. This contrasts with instructor-centered approaches to debriefing, where instructors maintain unilateral control over both the process and content of the debriefing, thus limiting input and direction from learners. Although different approaches to debriefing for simulation-based education exist, the simulation literature is largely mute on the topic of learner-centered debriefing. In this article we will (1) compare and contrast learner- versus instructor-centered approaches to teaching; (2) provide a rationale for applying more learner-centered approaches to debriefing; (3) introduce a conceptual framework that highlights the key dimensions of learner- versus instructor-centered debriefing; (4) describe key variables to consider when managing the balance between learner- and instructor-centered debriefing; and (5) describe practical learner-centered strategies for various phases of debriefing.",2016-02,26/11/2018 12:51,14/04/2020 08:34,,32-40,,1,11,,Simul Healthc,,,,,,,,eng,,,,,,,PMID: 26836466,,,,"Humans; Clinical Competence; Curriculum; Simulation Training/*methods; *Models, Educational; *Learning; 00; Educational Measurement/*methods; Education, Medical/*methods; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9Y89VZBS,journalArticle,2016,"Bowling, Ann M.; Underwood, Patricia W.","Effect of simulation on knowledge, self-confidence, and skill performance in the USA: A quasi-experimental study.",Nursing & health sciences,,1442-2018 1441-0745,10.1111/nhs.12267,,"In health care, high-fidelity simulation has been shown to result in increased student learning outcomes when compared to low-fidelity simulation. With educational facilities investing significant amounts of money into purchasing high-fidelity simulators, it is imperative to identify if the midlevel simulator, which is less costly, will result in the same learning outcomes. In this study, we examined the effect of midlevel-fidelity simulation versus low-fidelity simulation on Bachelor of Science in Nursing nursing students' knowledge, self-confidence, and skill performance. A quasi-experimental design examined the effects of midlevel-fidelity simulation (n = 37) versus low-fidelity simulation (case study) (n = 37) in junior-level nursing students. There was a significant difference for both groups in knowledge and skill performance (measured with a mini Objective Structured Clinical Examination), but not between the groups. Unexpectedly, the case-study group had a higher level of self-confidence (self-reported). The results of this study indicate that further research is needed to support faculties' selection of learning strategies with the lowest cost and highest effectiveness in achieving the desired learning outcomes.",2016-09,26/11/2018 12:51,14/04/2020 08:34,,292-298,,3,18,,Nurs Health Sci,,,,,,,,eng,"(c) 2016 John Wiley & Sons Australia, Ltd.",,,,,,PMID: 26834000,,,,"Humans; Adult; Female; Male; *Patient Simulation; Students, Nursing/*psychology; Health Knowledge, Attitudes, Practice; *Self Concept; simulation; 00; Education, Nursing, Baccalaureate/methods; nursing education; Objective Structured Clinical Examination; self-confidence; skill performance; Teaching/trends; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NJAGH4CI,journalArticle,2016,"Di Giorgio, Laura; Flaxman, Abraham D.; Moses, Mark W.; Fullman, Nancy; Hanlon, Michael; Conner, Ruben O.; Wollum, Alexandra; Murray, Christopher J. L.","Efficiency of Health Care Production in Low-Resource Settings: A Monte-Carlo Simulation to Compare the Performance of Data Envelopment Analysis, Stochastic Distance Functions, and an Ensemble Model.",PloS one,,1932-6203 1932-6203,10.1371/journal.pone.0147261,,"Low-resource countries can greatly benefit from even small increases in efficiency of health service provision, supporting a strong case to measure and pursue efficiency improvement in low- and middle-income countries (LMICs). However, the knowledge base concerning efficiency measurement remains scarce for these contexts. This study shows that current estimation approaches may not be well suited to measure technical efficiency in LMICs and offers an alternative approach for efficiency measurement in these settings. We developed a simulation environment which reproduces the characteristics of health service production in LMICs, and evaluated the performance of Data Envelopment Analysis (DEA) and Stochastic Distance Function (SDF) for assessing efficiency. We found that an ensemble approach (ENS) combining efficiency estimates from a restricted version of DEA (rDEA) and restricted SDF (rSDF) is the preferable method across a range of scenarios. This is the first study to analyze efficiency measurement in a simulation setting for LMICs. Our findings aim to heighten the validity and reliability of efficiency analyses in LMICs, and thus inform policy dialogues about improving the efficiency of health service production in these settings.",2016,26/11/2018 12:51,14/04/2020 08:34,,e0147261,,1,11,,PLoS One,,,,,,,,eng,,,,,,,PMID: 26812685 PMCID: PMC4727806,,,,"Delivery of Health Care/*organization & administration; Humans; Monte Carlo Method; Models, Theoretical; Efficiency, Organizational; Stochastic Processes; 1; Income; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, W5KFDW6Y,journalArticle,2015,"Riva, Giuseppe; Wiederhold, Brenda K.",The New Dawn of Virtual Reality in Health Care: Medical Simulation and Experiential Interface.,Studies in health technology and informatics,,0926-9630 0926-9630,,,"The 90s and 00s saw great hopes that virtual reality was poised to sweep health care and change everything. But it didn't. Though researchers could immerse themselves in more complex virtual environments, the chasm between that digital experience and the complexity of real life - using a VR system in an hospital without a dedicated technician was a real challenge - just was too great. Now the situation is changing quickly. The rise of Oculus Rift and the shift of virtual reality from PC to mobile phones thanks to both the Oculus designed Gear VR headsets for Samsung phones and the Google Cardboard project are going to transform health care tools and experiences.",2015,26/11/2018 12:51,14/04/2020 08:35,,03-Jun,,,219,,Stud Health Technol Inform,,,,,,,,eng,,,,,,,PMID: 26799868,,,,Humans; Patient Simulation; *User-Computer Interface; 00; *Medical Informatics/methods; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FHE3CGGU,journalArticle,2016,"Megiddo, Itamar; Colson, Abigail; Chisholm, Dan; Dua, Tarun; Nandi, Arindam; Laxminarayan, Ramanan",Health and economic benefits of public financing of epilepsy treatment in India: An agent-based simulation model.,Epilepsia,,1528-1167 0013-9580,10.1111/epi.13294,,"OBJECTIVE: An estimated 6-10 million people in India live with active epilepsy, and less than half are treated. We analyze the health and economic benefits of three scenarios of publicly financed national epilepsy programs that provide: (1) first-line antiepilepsy drugs (AEDs), (2) first- and second-line AEDs, and (3) first- and second-line AEDs and surgery. METHODS: We model the prevalence and distribution of epilepsy in India using IndiaSim, an agent-based, simulation model of the Indian population. Agents in the model are disease-free or in one of three disease states: untreated with seizures, treated with seizures, and treated without seizures. Outcome measures include the proportion of the population that has epilepsy and is untreated, disability-adjusted life years (DALYs) averted, and cost per DALY averted. Economic benefit measures estimated include out-of-pocket (OOP) expenditure averted and money-metric value of insurance. RESULTS: All three scenarios represent a cost-effective use of resources and would avert 800,000-1 million DALYs per year in India relative to the current scenario. However, especially in poor regions and populations, scenario 1 (which publicly finances only first-line therapy) does not decrease the OOP expenditure or provide financial risk protection if we include care-seeking costs. The OOP expenditure averted increases from scenarios 1 through 3, and the money-metric value of insurance follows a similar trend between scenarios and typically decreases with wealth. In the first 10 years of scenarios 2 and 3, households avert on average over US$80 million per year in medical expenditure. SIGNIFICANCE: Expanding and publicly financing epilepsy treatment in India averts substantial disease burden. A universal public finance policy that covers only first-line AEDs may not provide significant financial risk protection. Covering costs for both first- and second-line therapy and other medical costs alleviates the financial burden from epilepsy and is cost-effective across wealth quintiles and in all Indian states.",2016-03,26/11/2018 12:51,14/04/2020 08:34,,464-474,,3,57,,Epilepsia,,,,,,,,eng,"(c) 2016 The Authors. Epilepsia published by Wiley Periodicals, Inc. on behalf of International League Against Epilepsy.",,,,,,PMID: 26765291 PMCID: PMC5019268,,,,"Humans; Treatment Outcome; *Systems Analysis; India/epidemiology; Cost-effectiveness; India; *Cost of Illness; 1; Agent-based model; Cost-Benefit Analysis/*economics/methods; Epilepsy; Epilepsy/*economics/epidemiology/therapy; Financing, Government/*economics/methods; Insurance Benefits/*economics/methods; Universal public finance; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, C5ZZA32J,journalArticle,2016,"Kievit, Wietske; van Herwaarden, Noortje; van den Hoogen, Frank Hj; van Vollenhoven, Ronald F.; Bijlsma, Johannes Wj; van den Bemt, Bart Jf; van der Maas, Aatke; den Broeder, Alfons A.",Disease activity-guided dose optimisation of adalimumab and etanercept is a cost-effective strategy compared with non-tapering tight control rheumatoid arthritis care: analyses of the DRESS study.,Annals of the rheumatic diseases,,1468-2060 0003-4967,10.1136/annrheumdis-2015-208317,,"BACKGROUND: A disease activity-guided dose optimisation strategy of adalimumab or etanercept (TNFi (tumour necrosis factor inhibitors)) has shown to be non-inferior in maintaining disease control in patients with rheumatoid arthritis (RA) compared with usual care. However, the cost-effectiveness of this strategy is still unknown. METHOD: This is a preplanned cost-effectiveness analysis of the Dose REduction Strategy of Subcutaneous TNF inhibitors (DRESS) study, a randomised controlled, open-label, non-inferiority trial performed in two Dutch rheumatology outpatient clinics. Patients with low disease activity using TNF inhibitors were included. Total healthcare costs were measured and quality adjusted life years (QALY) were based on EQ5D utility scores. Decremental cost-effectiveness analyses were performed using bootstrap analyses; incremental net monetary benefit (iNMB) was used to express cost-effectiveness. RESULTS: 180 patients were included, and 121 were allocated to the dose optimisation strategy and 59 to control. The dose optimisation strategy resulted in a mean cost saving of -euro12 280 (95 percentile -euro10 502; -euro14 104) per patient per 18 months. There is an 84% chance that the dose optimisation strategy results in a QALY loss with a mean QALY loss of -0.02 (-0.07 to 0.02). The decremental cost-effectiveness ratio (DCER) was euro390 493 (euro5 085 184; dominant) of savings per QALY lost. The mean iNMB was euro10 467 (euro6553-euro14 037). Sensitivity analyses using 30% and 50% lower prices for TNFi remained cost-effective. CONCLUSIONS: Disease activity-guided dose optimisation of TNFi results in considerable cost savings while no relevant loss of quality of life was observed. When the minimal QALY loss is compensated with the upper limit of what society is willing to pay or accept in the Netherlands, the net savings are still high. TRIAL REGISTRATION NUMBER: NTR3216; Post-results.",2016-11,26/11/2018 12:51,14/04/2020 08:34,,1939-1944,,11,75,,Ann Rheum Dis,,,,,,,,eng,Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.,,,,,,PMID: 26764260,,,,"Humans; Netherlands; Quality-Adjusted Life Years; Health Care Costs; Female; Male; Middle Aged; *Cost-Benefit Analysis; Aged; Arthritis, Rheumatoid/*drug therapy/economics; 00; *Anti-TNF; *Economic Evaluations; *Outcomes research; *Rheumatoid Arthritis; Adalimumab/*administration & dosage/economics; Antirheumatic Agents/*administration & dosage/economics; Etanercept/*administration & dosage/economics; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BIHXR2AD,journalArticle,2015,"New, Sandra N.; Huff, Deborah Cooley; Hutchison, Lisa C.; Bilbruck, Timothy J.; Ragsdale, Patricia Sue; Jennings, Joy E.; Greenfield, M.",Integrating Collaborative Interprofessional Simulation into Pre-Licensure Health Care Programs.,Nursing education perspectives,,1536-5026 1536-5026,,,"This interprofessional education activity incorporated National League of Nursing unfolding case studies and patient simulation with nursing, pharmacy, and medical students. Faculty developed a full-day simulation experience; the most unique element was a team meeting where nursing students presented home health findings to an interprofessional team, and students worked together to design a comprehensive plan of care. All students were in their geriatric specialty program rotations. The interprofessional simulation introduced students across disciplines for the purpose of enhancing communication, developing mutual respect, and identifying role clarity through team learning.",2015-12,26/11/2018 12:51,14/04/2020 08:35,,396-397,,6,36,,Nurs Educ Perspect,,,,,,,,eng,,,,,,,PMID: 26753301,,,,"Humans; Male; *Patient Simulation; Curriculum; Interprofessional Relations; Aged, 80 and over; *Communication; Health Personnel/*education; Education, Nursing/*methods; Cooperative Behavior; 00; Students, Medical; Students, Nursing; Geriatric Nursing/*education; Education, Medical/*methods; Patient Care Planning/*organization & administration; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5N9FU8V8,journalArticle,2015,"Foronda, Cynthia L.; Alhusen, Jeanne; Budhathoki, Chakra; Lamb, Mary; Tinsley, Kim; MacWilliams, Brent; Daniels, Jessie; Baptiste, Diana Lyn; Reese, Kathie Kushto; Bauman, Eric","A Mixed-Methods, International, Multisite Study to Develop and Validate a Measure of Nurse-to-Physician Communication in Simulation.",Nursing education perspectives,,1536-5026 1536-5026,,,"AIM: This study examined the reliability and validity of the ISBAR Interprofessional Communication Rubric (IICR). BACKGROUND: Improving education regarding communication in health care is a global priority. Communication is difficult to measure and no evaluation rubrics were located that uniquely focused on nurse-to-physician communication in simulation. METHOD: This study used a mixed-methods design and included five sites. RESULTS: The IICR was determined reliable among nurse educator raters (r = 0.79). The scale was found valid as assessed by nurse and physician experts (content validity index = 0.92). When describing their experience of using the tool, nurse educator raters described three categories: overall acceptability of the tool, ease of use, and perceptions of the importance of communication skills for patient safety. CONCLUSION: Teaching and evaluating communication in simulation with a standardized rubric is a research area in need of further exploration and refinement.",2015-12,26/11/2018 12:51,14/04/2020 08:34,,383-388,,6,36,,Nurs Educ Perspect,,,,,,,,eng,,,,,,,PMID: 26753298,,,,"Humans; United States; *Simulation Training; Adult; Female; Male; Middle Aged; Nursing Education Research; Young Adult; Reproducibility of Results; Program Development; *Communication; *Interprofessional Relations; Education, Nursing/*methods; *Physicians; 1; Students, Medical; Education, Medical/*methods; *Nursing Staff; Chin; Psychometrics; Schools, Nursing; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NGSCP675,journalArticle,2017,"Standfield, L. B.; Comans, T. A.; Scuffham, P. A.",An empirical comparison of Markov cohort modeling and discrete event simulation in a capacity-constrained health care setting.,The European journal of health economics : HEPAC : health economics in prevention and care,,1618-7601 1618-7598,10.1007/s10198-015-0756-z,,OBJECTIVES: To empirically compare Markov cohort modeling (MM) and discrete event simulation (DES) with and without dynamic queuing (DQ) for cost-effectiveness (CE) analysis of a novel method of health services delivery where capacity constraints predominate. METHODS: A common data-set comparing usual orthopedic care (UC) to an orthopedic physiotherapy screening clinic and multidisciplinary treatment service (OPSC) was used to develop a MM and a DES without (DES-no-DQ) and with DQ (DES-DQ). Model results were then compared in detail. RESULTS: The MM predicted an incremental CE ratio (ICER) of $495 per additional quality-adjusted life-year (QALY) for OPSC over UC. The DES-no-DQ showed OPSC dominating UC; the,2017-01,26/11/2018 12:51,14/04/2020 08:35,,33-47,,1,18,,Eur J Health Econ,,,,,,,,eng,,,,,,,PMID: 26715578,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; *Models, Economic; *Markov Chains; Resource Allocation; Cost-effectiveness; Discrete event simulation; 00; DES; Dynamic queuing; Markov cohort; Orthopedics/*economics; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, W7EBYK86,journalArticle,2016,"Agarwal, Amit; Marks, Nancy; Wessel, Valerie; Willis, Denise; Bai, Shasha; Tang, Xinyu; Ward, Wendy L.; Schellhase, Dennis E.; Carroll, John L.","Improving knowledge, technical skills, and confidence among pediatric health care providers in the management of chronic tracheostomy using a simulation model.",Pediatric pulmonology,,1099-0496 1099-0496,10.1002/ppul.23355,,"OBJECTIVE: The results from a recent national survey about catastrophic complications following tracheostomy revealed that the majority of events involved a loss of airway. Most of the events due to airway loss involved potentially correctable deficits in caregiver education. Training in a simulated environment allows skill acquisition without compromising patient safety. We assessed the knowledge and confidence level of pediatric health care providers at a large tertiary care children's hospital in routine and emergency tracheostomy care and evaluated the efficacy of a comprehensive simulation-based tracheostomy educational program. METHODS: The prospective observational study was comprised of 33 subjects including pediatric residents, internal medicine-pediatric residents, pediatric hospitalist faculty physicians, and advanced practice registered nurses who are involved in the care of patients with tracheostomies within a tertiary-care children's hospital. The subjects completed self-assessment questionnaires and objective multiple-choice tests before and after attending a comprehensive educational course that employed patient simulation. The outcome measurements included pre- and post-course questionnaires, pre- and post-course test scores, and observational data from the simulation sessions. RESULTS: Before the education and simulation, the subjects' comfort and confidence levels on a five-point Likert scale in performing routine tracheostomy tube care, routine tracheostomy tube change, and an emergency tracheostomy tube change were as follows (median (Q1, Q3)): 1 (1, 2), 1 (1, 2), and 1 (1, 2), respectively (n = 28). The levels of comfort and confidence after completing the course improved significantly to 4 (4, 5), 4 (4, 5), 4 (4, 5), respectively (P < 0.001) (n = 20). For the knowledge assessment, the pre-course test mean score was 0.53 +/- 0.50, and the scores on the post-course test improved significantly with a mean score of 0.82 +/- 0.39 (P < 0.001). During the educational intervention, specific deficiencies observed included a lack of understanding or familiarity with different types of tracheostomy tubes (e.g., cuffed versus uncuffed), physiological significance of the cuff, mechanism of action and physiological significance of the speaking valve, and the importance of the obturator in changing the tracheostomy tube. CONCLUSION: There is a need for improved tracheostomy education among pediatric health care providers. Incorporation of patient-simulation into a tracheostomy educational program was effective in improving knowledge, confidence, and skills. Pediatr Pulmonol. 2016;51:696-704. (c) 2015 Wiley Periodicals, Inc.",2016-07,26/11/2018 12:51,14/04/2020 08:34,,696-704,,7,51,,Pediatr Pulmonol,,,,,,,,eng,"(c) 2015 Wiley Periodicals, Inc.",,,,,,PMID: 26681655,,,,"Humans; Surveys and Questionnaires; Disease Management; Patient Safety; Computer Simulation; *Clinical Competence; Health Personnel/*education; *Health Knowledge, Attitudes, Practice; Manikins; simulation; Hospitals, Pediatric; medical education; Tertiary Care Centers; 1; Pediatrics/*education; children; pediatric residents; tracheostomy; Tracheostomy/*education; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7LYB9IVB,journalArticle,2015,"Auchincloss, Amy H.; Garcia, Leandro Martin Totaro",Brief introductory guide to agent-based modeling and an illustration from urban health research.,Cadernos de saude publica,,1678-4464 0102-311X,10.1590/0102-311X00051615,,"There is growing interest among urban health researchers in addressing complex problems using conceptual and computation models from the field of complex systems. Agent-based modeling (ABM) is one computational modeling tool that has received a lot of interest. However, many researchers remain unfamiliar with developing and carrying out an ABM, hindering the understanding and application of it. This paper first presents a brief introductory guide to carrying out a simple agent-based model. Then, the method is illustrated by discussing a previously developed agent-based model, which explored inequalities in diet in the context of urban residential segregation.",2015-11,26/11/2018 12:51,14/04/2020 08:34,,65-78,,,31 Suppl 1,,Cad Saude Publica,,,,,,,,eng,,,,,,,PMID: 26648364 PMCID: PMC5391997,,,,"Humans; *Systems Analysis; Models, Theoretical; Brazil; 00; *Urban Health; Computer Simulation/*standards; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 46PAIRVE,journalArticle,2015,"Diez Roux, Ana V.",Health in cities: is a systems approach needed?,Cadernos de saude publica,,1678-4464 0102-311X,10.1590/0102-311XDE01S115,,"This paper reviews the potential utility of using the concepts and tools of systems to understand and act on health in cities. The basic elements of systems approaches and the links between cities as systems and population health as emerging from the functioning of a system are reviewed. The paper also discusses implications of systems thinking for urban health including the development of dynamic conceptual models, the use of new tools, the integration of data in new ways and the identification of data gaps, and the formulation of different kinds of questions and identification of new policies. The paper concludes with a review of caveats and challenges.",2015-11,26/11/2018 12:51,14/04/2020 08:34,,Sep-13,,,31 Suppl 1,,Cad Saude Publica,,,,,,,,eng,,,,,,,PMID: 26648353,,,,Humans; Healthcare Disparities; *Cities; Public Policy; Brazil; Social Determinants of Health; 00; Urban Population; *Urban Health; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MBWL7M4X,journalArticle,2017,"Rosas, Scott R.",Systems thinking and complexity: considerations for health promoting schools.,Health promotion international,,1460-2245 0957-4824,10.1093/heapro/dav109,,"The health promoting schools concept reflects a comprehensive and integrated philosophy to improving student and personnel health and well-being. Conceptualized as a configuration of interacting, interdependent parts connected through a web of relationships that form a whole greater than the sum of its parts, school health promotion initiatives often target several levels (e.g. individual, professional, procedural and policy) simultaneously. Health promoting initiatives, such as those operationalized under the whole school approach, include several interconnected components that are coordinated to improve health outcomes in complex settings. These complex systems interventions are embedded in intricate arrangements of physical, biological, ecological, social, political and organizational relationships. Systems thinking and characteristics of complex adaptive systems are introduced in this article to provide a perspective that emphasizes the patterns of inter-relationships associated with the nonlinear, dynamic and adaptive nature of complex hierarchical systems. Four systems thinking areas: knowledge, networks, models and organizing are explored as a means to further manage the complex nature of the development and sustainability of health promoting schools. Applying systems thinking and insights about complex adaptive systems can illuminate how to address challenges found in settings with both complicated (i.e. multi-level and multisite) and complex aspects (i.e. synergistic processes and emergent outcomes).",01/04/2017,26/11/2018 12:51,14/04/2020 08:35,,301-311,,2,32,,Health Promot Int,,,,,,,,eng,"(c) The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.",,,,,,PMID: 26620709,,,,"Humans; *Systems Analysis; systems thinking; Models, Organizational; complexity; 1; *Thinking; Students/psychology; health promoting schools; Health Promotion/methods/*organization & administration; Schools/*organization & administration; Social Environment; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, X7785CQE,journalArticle,2016,"Igarashi, Ataru; Goto, Rei; Suwa, Kiyomi; Yoshikawa, Reiko; Ward, Alexandra J.; Moller, Jorgen",Cost-Effectiveness Analysis of Smoking Cessation Interventions in Japan Using a Discrete-Event Simulation.,Applied health economics and health policy,,1179-1896 1175-5652,10.1007/s40258-015-0204-3,,"BACKGROUND: Smoking cessation medications have been shown to yield higher success rates and sustained abstinence than unassisted quit attempts. In Japan, the treatments available include nicotine replacement therapy (NRT) and varenicline; however, unassisted attempts to quit smoking remain common. OBJECTIVE: The objective of this study was to compare the health and economic consequences in Japan of using pharmacotherapy to support smoking cessation with unassisted attempts and the current mix of strategies used. METHODS: A discrete-event simulation that models lifetime quitting behaviour and includes multiple quit attempts (MQAs) and relapses was adapted for these analyses. The risk of developing smoking-related diseases is estimated based on the duration of abstinence. Data collected from a survey conducted in Japan were used to determine the interventions selected by smokers initiating a quit attempt and the time between MQAs. Direct and indirect costs are assessed (expressed in 2014 Japanese Yen). RESULTS: Using pharmacotherapy (NRT or varenicline) to support quit attempts proved to be dominant when compared with unassisted attempts or the current mix of strategies (most are unassisted). The results of stratified analyses by age imply that smoking cessation improves health outcomes across all generations. Indirect costs due to premature death leading to lost wages are an important component of the total costs, exceeding the direct medical cost estimates. CONCLUSIONS: Increased utilisation of smoking cessation pharmacotherapy to support quit attempts is predicted to lead to an increase in the number of smokers achieving abstinence, and provide improvements in health outcomes over a lifetime with no additional costs.",2016-02,26/11/2018 12:51,14/04/2020 08:34,,77-87,,1,14,,Appl Health Econ Health Policy,,,,,,,,eng,,,,,,,PMID: 26597111 PMCID: PMC4740570,,,,Humans; Quality-Adjusted Life Years; Adult; Female; Male; Middle Aged; Young Adult; Aged; Health Care Costs/statistics & numerical data; Adolescent; Cost-Benefit Analysis/*methods; Japan; Smoking Cessation/*economics/methods; Smoking/adverse effects/economics; Tobacco Use Cessation Products/economics; Varenicline/economics/therapeutic use; Discrete event simulation; 1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CD22X5U5,journalArticle,2015,"Wallden, Matt","""But we're infinitely more complex than a car"": A systems approach to health & performance.",Journal of bodywork and movement therapies,,1532-9283 1360-8592,10.1016/j.jbmt.2015.09.002,,,2015-10,26/11/2018 12:51,14/04/2020 08:35,,697-711,,4,19,,J Bodyw Mov Ther,,,,,,,,eng,,,,,,,PMID: 26592227,,,,Humans; *Health Status; Exercise; *Health Behavior; Diet; Life Style; 00; *Holistic Health; Genetic Predisposition to Disease; Low Back Pain/physiopathology/rehabilitation; Movement/*physiology; Musculoskeletal Manipulations/*organization & administration; 100; ****more for intro,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TVXT92AH,journalArticle,2015,"Gedlu, Etsegenet; Tadesse, Amezene; Cayea, Danelle; Doherty, Meg; Bekele, Abebe; Mekasha, Amha; Derbew, Miliard; Jung, Julianna",INTRODUCTION OF SIMULATION BASED MEDICAL EDUCATION AT ADDIS ABABA UNIVERSITY COLLEGE OF HEALTH SCIENCES: EXPERIENCE AND CHALLENGE.,Ethiopian medical journal,,0014-1755 0014-1755,,,"BACKGROUND: As one of the countries in Sub-Saharan Africa with a low physician to population ratio, Ethiopia has sought to mitigate the problem by increasing the number of students enrolling in the existing medical schools. This increase in enrolment was not accompanied by expansion of clinical training venues, which has resulted in less patient contact time for each student. As part of the solution to fill the gap simulation-based teaching was introduced. OBJECTIVE: To describe the process of introducing Simulation based medical education (SBME) at Addis Ababa University College of Health Sciences, school of medicine. METHODS: Two rounds of intensive training was given by John Hopkins in collaboration with Medical Education partner Initiative (MEPI). to the core clinical educators to introduce them the six-step model of curriculum development for medical education and standardized patient (SP) techniques with the ultimate aim of introducing SPs in the teaching and learning process for medical students. The training included didactic and workshop elements, with group work and created complete educational modules. Each pre and post course assessment of experience and attitude were surveyed. Data was analyzed in aggregate using paired t -test to compare pre and post course means. RESULTS: There were total of 22 faculty members participated in the first group ,the majority of whom had no prior training in curriculum development or SBME and were skeptical of the value of SBME, as evidenced in their survey responses. (3.42/5 in Likert scale 1 = least 5 = most) at the end of the course the participant were comfortable with the concept of curriculum development the rating increased to 4.45/5 (P < 0.0001) and they embraced more favorable attitudes regarding the feasibility and desirability of simulation with Likert Scale 4.01/5 to 4.51 (P < 0.0001). In the second course, there were 16 participant and the majority had no prior experience with simulation and/or SP encounters. Their Baseline attitudes among participants in the second course were more favourable than in the first course, with a mean precourse Likert score of 4.24/5. Mean post course score was 4.43/5 (p = 0.1003), which did not represent a significant increase. The largest pre/post increases were seen for questions regarding accuracy of SP portrayal of specific clinical conditions (3.93 to 4.43, p = 0.0011), and enjoyability of incorporating SP activities into curricula (4.33 to 4.73, p = 0. 0281). After the course, the faculty remained particularly sceptical of the role of SPs in grading students (3.43/5). Both courses were well received, with 95% reporting they learned what they had hoped to learn. CONCLUSION: Training courses at CHS were successful for generating enthusiasm about simulation, and improving participant attitudes regarding the usefulness and feasibility of this educational method.",2015-07,26/11/2018 12:51,14/04/2020 08:34,,01-Aug,,,Suppl 2,,Ethiop Med J,,,,,,,,eng,,,,,,,PMID: 26591277,,,,"Humans; *Patient Simulation; Curriculum; Teaching/*methods; Maryland; 00; Schools, Medical; Education, Medical, Undergraduate/*methods; Ethiopia; International Cooperation; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DE3H8ETL,journalArticle,2016,"Kalton, Alan; Falconer, Erin; Docherty, John; Alevras, Dimitris; Brann, David; Johnson, Kyle",Multi-Agent-Based Simulation of a Complex Ecosystem of Mental Health Care.,Journal of medical systems,,1573-689X 0148-5598,10.1007/s10916-015-0374-4,,"This paper discusses the creation of an Agent-Based Simulation that modeled the introduction of care coordination capabilities into a complex system of care for patients with Serious and Persistent Mental Illness. The model describes the engagement between patients and the medical, social and criminal justice services they interact with in a complex ecosystem of care. We outline the challenges involved in developing the model, including process mapping and the collection and synthesis of data to support parametric estimates, and describe the controls built into the model to support analysis of potential changes to the system. We also describe the approach taken to calibrate the model to an observable level of system performance. Preliminary results from application of the simulation are provided to demonstrate how it can provide insights into potential improvements deriving from introduction of care coordination technology.",2016-02,26/11/2018 12:51,14/04/2020 08:34,,39,,2,40,,J Med Syst,,,,,,,,eng,,,,,,,PMID: 26590977 PMCID: PMC4655012,,,,"Humans; Computer Simulation; *Models, Theoretical; 1; Model development; Mental Disorders/*therapy; Agent-based simulation; Care coordination; Complex medical and social ecosystem; Criminology/*organization & administration; Mental health care; Mental Health Services/*organization & administration; Patient Care Management/*organization & administration; Psychiatric patient environment; Social Work/*organization & administration; System management; 320",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PP5VH3RV,journalArticle,2015,"Gibson, Caroline E.; Dickson, Caroline; Lawson, Bill; Kelly, Helena; McMillan, Ailsa",Learning to deal with crisis in the home: Part 1--developing community simulation scenarios.,British journal of community nursing,,1462-4753 1462-4753,10.12968/bjcn.2015.20.11.536,,"Contemporary health care is increasingly being located in the community. From the evident changes in demographics and general health, it can be derived that the people whom student nurses care for are likely to have multiple comorbidities and be vulnerable to clinical deterioration. These nurses are required to develop a range of transferrable skills to meet the demands of the population. The challenge for educators of preregistration student nurses is to develop educational strategies to prepare them with the skills, knowledge, and confidence necessary to recognise and manage deterioration appropriately in any context. This article is the first of two papers discussing the stimulus, design, and delivery of an educational innovation that focuses on the recognition and management of the deteriorating patient. The article explores current literature about community-focused simulation highlighting the potential learning opportunities resulting from contextualising simulation scenarios specific to the community setting.",2015-11,26/11/2018 12:51,14/04/2020 08:34,,536-540,,11,20,,Br J Community Nurs,,,,,,,,eng,,,,,,,PMID: 26551382,,,,"Humans; *Patient Simulation; Education, Nursing, Baccalaureate; State Medicine; Community Health Nursing/*education; *Problem-Based Learning; education; 00; patient simulation; deterioration; Emergencies/*nursing; problem-based learning; Scotland; transfer of learning; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KTKJIECT,journalArticle,2015,"Schwindt, Rhonda; McNelis, Angela",Integrating Simulation into a Reflection-Centered Graduate Psychiatric/Mental Health Nursing Curriculum.,Nursing education perspectives,,1536-5026 1536-5026,,,"The purpose of this qualitative study was to explore reflections of student learning following a simulation experience integrated into a psychiatric/mental health nurse practitioner course. As the demand for clinical placement sites increases and availability of preceptors declines, students require experiences that will prepare them for competent patient care. This experiential learning activity was grounded in reflection-centered pedagogy, utilizing standardized patients. Three main themes emerged from the data: importance of feedback, insight gained, and improved confidence. Findings suggest that simulation is a promising approach to promote the development of competencies in graduate nursing education.",2015-10,26/11/2018 12:51,14/04/2020 08:35,,326-328,,5,36,,Nurs Educ Perspect,,,,,,,,eng,,,,,,,PMID: 26521503,,,,"Humans; Clinical Competence; Nursing Education Research; Curriculum; Psychiatric Nursing/*education; Educational Measurement; Models, Educational; Patient Simulation; Feedback; 00; Education, Nursing, Graduate/*methods; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4SHEQ7CV,journalArticle,2015,"Milton, Sarah; Pliakas, Triantafyllos; Hawkesworth, Sophie; Nanchahal, Kiran; Grundy, Chris; Amuzu, Antoinette; Casas, Juan-Pablo; Lock, Karen",A qualitative geographical information systems approach to explore how older people over 70 years interact with and define their neighbourhood environment.,Health & place,,1873-2054 1353-8292,10.1016/j.healthplace.2015.10.002,,"A growing body of literature explores the relationship between the built environment and health, and the methodological challenges of understanding these complex interactions across the lifecourse. The impact of the neighbourhood environment on health and behaviour amongst older adults has received less attention, despite this age group being potentially more vulnerable to barriers in their surrounding social and physical environment. A qualitative geographical information systems (QGIS) approach was taken to facilitate the understanding of how older people over 70 in 5 UK towns interact with their local neighbourhood. The concept of neighbourhood changed seasonally and over the lifecourse, and was associated with social factors such as friends, family, or community activities, rather than places. Spaces stretched further than the local, which is problematic for older people who rely on variable public transport provision. QGIS techniques prompted rich discussions on interactions with and the meanings of 'place' in older people.",2015-11,26/11/2018 12:51,14/04/2020 08:34,,127-133,,,36,,Health Place,,,,,,,,eng,Copyright (c) 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.,,,,,,PMID: 26513597 PMCID: PMC4676086,,,,"Humans; Female; Male; Environment; Aged; Qualitative Research; *Environment; Aged, 80 and over; Pilot Projects; United Kingdom; Prospective Studies; Interviews as Topic; Aging; 00; Geographic Information Systems; Methods; *Residence Characteristics; *Urban Population; Ageing; Neighbourhood; Qualitative geographical information systems; Space; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DA72XF7S,journalArticle,2016,"Marshall, Deborah A.; Burgos-Liz, Lina; Pasupathy, Kalyan S.; Padula, William V.; IJzerman, Maarten J.; Wong, Peter K.; Higashi, Mitchell K.; Engbers, Jordan; Wiebe, Samuel; Crown, William; Osgood, Nathaniel D.",Transforming Healthcare Delivery: Integrating Dynamic Simulation Modelling and Big Data in Health Economics and Outcomes Research.,PharmacoEconomics,,1179-2027 1170-7690,10.1007/s40273-015-0330-7,,"In the era of the Information Age and personalized medicine, healthcare delivery systems need to be efficient and patient-centred. The health system must be responsive to individual patient choices and preferences about their care, while considering the system consequences. While dynamic simulation modelling (DSM) and big data share characteristics, they present distinct and complementary value in healthcare. Big data and DSM are synergistic-big data offer support to enhance the application of dynamic models, but DSM also can greatly enhance the value conferred by big data. Big data can inform patient-centred care with its high velocity, volume, and variety (the three Vs) over traditional data analytics; however, big data are not sufficient to extract meaningful insights to inform approaches to improve healthcare delivery. DSM can serve as a natural bridge between the wealth of evidence offered by big data and informed decision making as a means of faster, deeper, more consistent learning from that evidence. We discuss the synergies between big data and DSM, practical considerations and challenges, and how integrating big data and DSM can be useful to decision makers to address complex, systemic health economics and outcomes questions and to transform healthcare delivery.",2016-02,26/11/2018 12:51,14/04/2020 08:34,,115-126,,2,34,,Pharmacoeconomics,,,,,,,,eng,,,,,,,PMID: 26497003,,,,"Delivery of Health Care/*organization & administration; Humans; Outcome Assessment (Health Care)/*methods; Decision Making; Computer Simulation; *Models, Theoretical; System dynamics; 1; *Economics, Medical; Patient-Centered Care/organization & administration; Precision Medicine/methods; 320",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6PKEN4G6,journalArticle,2015,"Khorana, Alok A.",A health systems approach to risk stratification.,Thrombosis research,,1879-2472 0049-3848,10.1016/j.thromres.2015.10.008,,"In 2008, my colleagues and I published a risk stratification tool to identify ambulatory cancer patients at high risk for venous thromboembolism (VTE), an increasingly common, morbid and potentially lethal complication of malignancy [1]. This study, funded by the National Cancer Institute, characterized the association of VTE with multiple variables in a derivation cohort of 2701 cancer outpatients from a prospective observational registry. A risk model was derived and validated in an independent cohort of 1365 patients from the same registry — a split sample approach to model validation.",2015-12,26/11/2018 12:51,14/04/2020 08:34,,1049-1050,,6,136,,Thromb Res,,,,,,,,eng,,,,,,,PMID: 26476742,,,,Humans; Risk Factors; *Risk Assessment; *Systems Analysis; 1; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 35ZJRNLC,journalArticle,2015,"Wong, Carlos K. H.; Lam, Cindy L. K.; Wan, Y. F.; Fong, Daniel Y. T.","Cost-effectiveness simulation and analysis of colorectal cancer screening in Hong Kong Chinese population: comparison amongst colonoscopy, guaiac and immunologic fecal occult blood testing.",BMC cancer,,1471-2407 1471-2407,10.1186/s12885-015-1730-y,,"BACKGROUND: The aim of this study was to evaluate the cost-effectiveness of CRC screening strategies from the healthcare service provider perspective based on Chinese population. METHODS: A Markov model was constructed to compare the cost-effectiveness of recommended screening strategies including annual/biennial guaiac fecal occult blood testing (G-FOBT), annual/biennial immunologic FOBT (I-FOBT), and colonoscopy every 10 years in Chinese aged 50 year over a 25-year period. External validity of model was tested against data retrieved from published randomized controlled trials of G-FOBT. Recourse use data collected from Chinese subjects among staging of colorectal neoplasm were combined with published unit cost data ($USD in 2009 price values) to estimate a stage-specific cost per patient. Quality-adjusted life-years (QALYs) were quantified based on the stage duration and SF-6D preference-based value of each stage. The cost-effectiveness outcome was the incremental cost-effectiveness ratio (ICER) represented by costs per life-years (LY) and costs per QALYs gained. RESULTS: In base-case scenario, the non-dominated strategies were annual and biennial I-FOBT. Compared with no screening, the ICER presented $20,542/LYs and $3155/QALYs gained for annual I-FOBT, and $19,838/LYs gained and $2976/QALYs gained for biennial",15/10/2015,26/11/2018 12:51,14/04/2020 08:35,,705,,,15,,BMC Cancer,,,,,,,,eng,,,,,,,PMID: 26471036 PMCID: PMC4608156,,,,Humans; Quality-Adjusted Life Years; Female; Male; Middle Aged; *Cost-Benefit Analysis; Aged; *Colonoscopy; *Early Detection of Cancer; Colorectal Neoplasms/*diagnosis/economics/pathology; Feces; Guaiac/administration & dosage; Hong Kong; Mass Screening; Occult Blood; 00; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EXUJBBBD,journalArticle,2015,"Arrospide, Arantzazu; Rue, Montserrat; van Ravesteyn, Nicolien T.; Comas, Merce; Larranaga, Nerea; Sarriugarte, Garbine; Mar, Javier",Evaluation of health benefits and harms of the breast cancer screening programme in the Basque Country using discrete event simulation.,BMC cancer,,1471-2407 1471-2407,10.1186/s12885-015-1700-4,,"BACKGROUND: Since the breast cancer screening programme in the Basque Country (BCSPBC) was started in 1996, more than 400,000 women aged 50 to 69 years have been invited to participate. Based on epidemiological observations and simulation techniques it is possible to extend observed short term data into anticipated long term results. The aim of this study was to assess the effectiveness of the programme through 2011 by quantifying the outcomes in breast cancer mortality, life-years gained, false positive results, and overdiagnosis. METHODS: A discrete event simulation model was constructed to reproduce the natural history of breast cancer (disease-free, pre-clinical, symptomatic, and disease-specific death) and the actual observed characteristics of the screening programme during the evaluated period in the Basque women population. Goodness-of-fit statistics were applied for model validation. The screening effects were measured as differences in benefits and harms between the screened and unscreened populations. Breast cancer mortality reduction and life-years gained were considered as screening benefits, whereas, overdiagnosis and false positive results were assessed as harms. Results for a single cohort were also obtained. RESULTS: The screening programme yielded a 16 % reduction in breast cancer mortality and a 10 % increase in the incidence of breast cancer through 2011. Almost 2 % of all the women in the programme had a false positive result during the evaluation period. When a single cohort was analysed, the number of deaths decreased by 13 %, and 4 % of screen-detected cancers were overdiagnosed. Each woman with BC detected by the screening programme gained 2.5 life years due to early detection corrected by lead time. CONCLUSIONS: Fifteen years after the screening programme started, this study supports an important decrease in breast cancer mortality due to the screening programme, with reasonable risk of overdiagnosis and false positive results, and sustains the continuation of the breast cancer screening programme in the Basque population.",12/10/2015,26/11/2018 12:51,14/04/2020 08:34,,671,,,15,,BMC Cancer,,,,,,,,eng,,,,,,,PMID: 26459293 PMCID: PMC4603694,,,,Humans; Female; Middle Aged; Aged; Risk Assessment; Incidence; Registries; Mortality; discrete event simulation; 1; *Mass Screening/methods; Breast Neoplasms/*epidemiology; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, AFXWV7EA,journalArticle,2015,"Auffermann, William F.; Henry, Travis S.; Little, Brent P.; Tigges, Stefan; Tridandapani, Srini",Simulation for Teaching and Assessment of Nodule Perception on Chest Radiography in Nonradiology Health Care Trainees.,Journal of the American College of Radiology : JACR,,1558-349X 1546-1440,10.1016/j.jacr.2015.07.014,,"PURPOSE: Simulation has been used as an educational and assessment tool in several fields, generally involving training of physical skills. To date, simulation has found limited application in teaching and assessment of skills related to image perception and interpretation. The goal of this pilot study was to evaluate the feasibility of simulation as a tool for teaching and assessment of skills related to perception of nodules on chest radiography. METHODS: This study received an exemption from the institutional review board. Subjects consisted of nonradiology health care trainees. Subjects underwent training and assessment of pulmonary nodule identification skills on chest radiographs at simulated radiology workstations. Subject performance was quantified by changes in area under the localization receiver operating characteristic curve. At the conclusion of the study, all subjects were given a questionnaire with five questions comparing learning at a simulated workstation with training using conventional materials. Statistical significance for questionnaire responses was tested using the Wilcoxon signed rank test. RESULTS: Subjects demonstrated statistically significant improvement in nodule identification after training at a simulated radiology workstation (change in area under the curve, 0.1079; P = .015). Subjects indicated that training on simulated radiology workstations was preferable to conventional training methods for all questions; P values for all questions were less than .01. CONCLUSIONS: Simulation may be a useful tool for teaching and assessment of skills related to medical image perception and interpretation. Further study is needed to determine which skills and trainee populations may be most amenable to training and assessment using simulation.",2015-11,26/11/2018 12:51,14/04/2020 08:34,,1215-1222,,11,12,,J Am Coll Radiol,,,,,,,,eng,Copyright (c) 2015 American College of Radiology. Published by Elsevier Inc. All rights reserved.,,,,,,PMID: 26421854,,,,"Humans; Surveys and Questionnaires; Adult; Female; Male; Curriculum; Health Personnel/education; *Computer Simulation; *Clinical Competence; Pilot Projects; Educational Measurement; Feasibility Studies; simulation; education; Perception; 00; *Radiography, Thoracic; Area Under Curve; perception; Radiology; Radiology/*education; ROC Curve; Solitary Pulmonary Nodule/*diagnostic imaging; Statistics, Nonparametric; Students, Medical/statistics & numerical data; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, N75UGJ4G,journalArticle,2015,"Yu, Tzy-Chyi; Zhou, Huanxue",Evaluation of techniques for handling missing cost-to-charge ratios in the USA Nationwide Inpatient Sample: a simulation study.,Journal of comparative effectiveness research,,2042-6313 2042-6305,10.2217/cer.15.28,,"AIM: Evaluate performance of techniques used to handle missing cost-to-charge ratio (CCR) data in the USA Healthcare Cost and Utilization Project's Nationwide Inpatient Sample. METHODS: Four techniques to replace missing CCR data were evaluated: deleting discharges with missing CCRs (complete case analysis), reweighting as recommended by Healthcare Cost and Utilization Project, reweighting by adjustment cells and hot deck imputation by adjustment cells. Bias and root mean squared error of these techniques on hospital cost were evaluated in five disease cohorts. RESULTS & CONCLUSION: Similar mean cost estimates would be obtained with any of the four techniques when the percentage of missing data is low (<10%). When total cost is the outcome of interest, a reweighting technique to avoid underestimation from dropping observations with missing data should be adopted.",2015-09,26/11/2018 12:51,14/04/2020 08:35,,473-483,,5,4,,J Comp Eff Res,,,,,,,,eng,,,,,,,PMID: 26387587,,,,"Humans; United States; Research Design; Data Interpretation, Statistical; 00; Comparative Effectiveness Research/*methods; cost-to-charge ratio; Hospital Costs/*statistics & numerical data; hospitalization costs; Inpatients/*statistics & numerical data; missing data; Nationwide Inpatient Sample; reweighting; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IT5QKZI8,journalArticle,2015,"Scanlon, Peter H.; Aldington, Stephen J.; Leal, Jose; Luengo-Fernandez, Ramon; Oke, Jason; Sivaprasad, Sobha; Gazis, Anastasios; Stratton, Irene M.",Development of a cost-effectiveness model for optimisation of the screening interval in diabetic retinopathy screening.,"Health technology assessment (Winchester, England)",,2046-4924 1366-5278,10.3310/hta19740,,"BACKGROUND: The English NHS Diabetic Eye Screening Programme was established in 2003. Eligible people are invited annually for digital retinal photography screening. Those found to have potentially sight-threatening diabetic retinopathy (STDR) are referred to surveillance clinics or to Hospital Eye Services. OBJECTIVES: To determine whether personalised screening intervals are cost-effective. DESIGN: Risk factors were identified in Gloucestershire, UK using survival modelling. A probabilistic decision hidden (unobserved) Markov model with a misgrading matrix was developed. This informed estimation of lifetime costs and quality-adjusted life-years (QALYs) in patients without STDR. Two personalised risk stratification models were employed: two screening episodes (SEs) (low, medium or high risk) or one SE with clinical information (low, medium-low, medium-high or high risk). The risk factor models were validated in other populations. SETTING: Gloucestershire, Nottinghamshire, South London and East Anglia (all UK). PARTICIPANTS: People with diabetes in Gloucestershire with risk stratification model validation using data from Nottinghamshire, South London and East Anglia. MAIN OUTCOME MEASURES: Personalised risk-based algorithm for screening interval; cost-effectiveness of different screening intervals. RESULTS: Data were obtained in Gloucestershire from 12,790 people with diabetes with known risk factors to derive the risk estimation models, from 15,877 people to inform the uptake of screening and from 17,043 people to inform the health-care resource-usage costs. Two stratification models were developed: one using only results from previous screening events and one using previous screening and some commonly available GP data. Both models were capable of differentiating groups at low and high risk of development of STDR. The rate of progression to STDR was 5 per 1000 person-years (PYs) in the lowest decile of risk and 75 per 1000 PYs in the highest decile. In the absence of personalised risk stratification, the most cost-effective screening interval was to screen all patients every 3 years, with a 46% probability of this being cost-effective at a pound30,000 per QALY threshold. Using either risk stratification models, screening patients at low risk every 5 years was the most cost-effective option, with a probability of 99-100% at a pound30,000 per QALY threshold. For the medium-risk groups screening every 3 years had a probability of 43-48% while screening high-risk groups every 2 years was cost-effective with a probability of",2015-09,26/11/2018 12:51,14/04/2020 08:34,,1-116,,74,19,,Health Technol Assess,,,,,,,,eng,,,,,,,PMID: 26384314 PMCID: PMC4780979,,,,"Humans; Outcome Assessment (Health Care); Female; Male; Middle Aged; Risk Factors; *Cost-Benefit Analysis; Aged; Models, Theoretical; Time Factors; Diabetic Retinopathy/epidemiology/*prevention & control; Mass Screening/*economics; Technology Assessment, Biomedical/economics; United Kingdom/epidemiology; 00; Review",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RTRXXTIQ,journalArticle,2015,"Kruger, Jen; Pollard, Daniel; Basarir, Hasan; Thokala, Praveen; Cooke, Debbie; Clark, Marie; Bond, Rod; Heller, Simon; Brennan, Alan",Incorporating Psychological Predictors of Treatment Response into Health Economic Simulation Models: A Case Study in Type 1 Diabetes.,Medical decision making : an international journal of the Society for Medical Decision Making,,1552-681X 0272-989X,10.1177/0272989X15590143,,"BACKGROUND: . Health economic modeling has paid limited attention to the effects that patients' psychological characteristics have on the effectiveness of treatments. This case study tests 1) the feasibility of incorporating psychological prediction models of treatment response within an economic model of type 1 diabetes, 2) the potential value of providing treatment to a subgroup of patients, and 3) the cost-effectiveness of providing treatment to a subgroup of responders defined using 5 different algorithms. METHODS: . Multiple linear regressions were used to investigate relationships between patients' psychological characteristics and treatment effectiveness. Two psychological prediction models were integrated with a patient-level simulation model of type 1 diabetes. Expected value of individualized care analysis was undertaken. Five different algorithms were used to provide treatment to a subgroup of predicted responders. A cost-effectiveness analysis compared using the algorithms to providing treatment to all patients. RESULTS: . The psychological prediction models had low predictive power for treatment effectiveness. Expected value of individualized care results suggested that targeting education at responders could be of value. The cost-effectiveness analysis suggested, for all 5 algorithms, that providing structured education to a subgroup of predicted responders would not be cost-effective. LIMITATIONS: . The psychological prediction models tested did not have sufficient predictive power to make targeting treatment cost-effective. The psychological prediction models are simple linear models of psychological behavior. Collection of data on additional covariates could potentially increase statistical power. CONCLUSIONS: . By collecting data on psychological variables before an intervention, we can construct predictive models of treatment response to interventions. These predictive models can be incorporated into health economic models to investigate more complex service delivery and reimbursement strategies.",2015-10,26/11/2018 12:51,14/04/2020 08:34,,872-887,,7,35,,Med Decis Making,,,,,,,,eng,(c) The Author(s) 2015.,,,,,,PMID: 26377675,,,,"Humans; Cost-Benefit Analysis; *Models, Economic; Algorithms; 00; *decision analysis; *cost utility analysis; *logistic regression models; *simulation methods; Diabetes Mellitus, Type 1/psychology/*therapy; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5TLL7VZ4,journalArticle,2015,"Johnson, Karen E.; Guillet, Nancy; Murphy, Linda; Horton, Shalonda E. B.; Todd, Ana T.","""If Only We Could Have Them Walk a Mile in Their Shoes"": A Community-Based Poverty Simulation Exercise for Baccalaureate Nursing Students.",The Journal of nursing education,,1938-2421 0148-4834,10.3928/01484834-20150814-22,,"BACKGROUND: Poverty is linked to poorer health outcomes across the life span. Nurses must understand how poverty impacts health and the ability to achieve social mobility. This article describes a poverty simulation exercise, In Their Shoes. METHOD: Scenarios of clients in need of community resources were developed. Using public transportation, students travelled to agencies to collect information about accessing resources. Students were introduced to content about poverty, income inequality, social mobility, and critical social theory prior to the simulation exercise. After the simulation, students returned to the classroom and reflected on the experience. RESULTS: In Their Shoes received positive feedback. Students expressed surprise at the number of community resources, frustration by the challenges encountered, and dedication to being aware and compassionate advocates for underserved clients. CONCLUSION: Nursing programs should develop and evaluate similar activities to expose students to the challenges of living in poverty, and how this affects health and nursing practice.",2015-09,26/11/2018 12:51,14/04/2020 08:34,,S116-119,,9,54,,J Nurs Educ,,,,,,,,eng,"Copyright 2015, SLACK Incorporated.",,,,,,PMID: 26334658,,,,"Humans; Adult; Female; Male; Nursing Education Research; Students, Nursing/*psychology; Simulation Training/*methods; *Attitude of Health Personnel; Education, Nursing, Baccalaureate/*methods; *Poverty; *Health Services Accessibility; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 55LGRYX6,journalArticle,2015,"Marini, Simone; Trifoglio, Emanuele; Barbarini, Nicola; Sambo, Francesco; Di Camillo, Barbara; Malovini, Alberto; Manfrini, Marco; Cobelli, Claudio; Bellazzi, Riccardo",A Dynamic Bayesian Network model for long-term simulation of clinical complications in type 1 diabetes.,Journal of biomedical informatics,,1532-0480 1532-0464,10.1016/j.jbi.2015.08.021,,"The increasing prevalence of diabetes and its related complications is raising the need for effective methods to predict patient evolution and for stratifying cohorts in terms of risk of developing diabetes-related complications. In this paper, we present a novel approach to the simulation of a type 1 diabetes population, based on Dynamic Bayesian Networks, which combines literature knowledge with data mining of a rich longitudinal cohort of type 1 diabetes patients, the DCCT/EDIC study. In particular, in our approach we simulate the patient health state and complications through discretized variables. Two types of models are presented, one entirely learned from the data and the other partially driven by literature derived knowledge. The whole cohort is simulated for fifteen years, and the simulation error (i.e. for each variable, the percentage of patients predicted in the wrong state) is calculated every year on independent test data. For each variable, the population predicted in the wrong state is below 10% on both models over time. Furthermore, the distributions of real vs. simulated patients greatly overlap. Thus, the proposed models are viable tools to support decision making in type 1 diabetes.",2015-10,26/11/2018 12:51,14/04/2020 08:34,,369-376,,,57,,J Biomed Inform,,,,,,,,eng,Copyright (c) 2015 Elsevier Inc. All rights reserved.,,,,,,PMID: 26325295,,,,"Humans; *Computer Simulation; *Bayes Theorem; Simulation; CVD; 1; *Data Mining; *Diabetes Complications; *Diabetes Mellitus, Type 1; Dynamic Bayesian Network; Nephropaty; Tabu search; Type 1 diabetes; 420",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, K85WV7F4,journalArticle,2015,"Kalkhoran, Sara; Glantz, Stanton A.",Modeling the Health Effects of Expanding e-Cigarette Sales in the United States and United Kingdom: A Monte Carlo Analysis.,JAMA internal medicine,,2168-6114 2168-6106,10.1001/jamainternmed.2015.4209,,"IMPORTANCE: The prevalence of electronic cigarette (e-cigarette) use is increasing. Population health effects will depend on cigarette smoking behaviors, levels of dual use with conventional cigarettes, and e-cigarette toxicity. OBJECTIVE: To evaluate potential health effects of various scenarios of increasing promotion and use of e-cigarettes. DESIGN, SETTING, AND PARTICIPANTS: A base case model was developed using data on actual cigarette and e-cigarette use patterns that quantifies transitions from an initial state of no cigarette or e-cigarette use to 1 of 5 final states: never use of cigarettes or e-cigarettes, cigarette use, e-cigarette use, dual use of cigarettes and e-cigarettes, or quit. Seven scenarios were created that cover a range of use patterns, depending on how the e-cigarette market might develop, as well as a range of possible long-term health effects of e-cigarette use. Scenarios for changes from the base case were evaluated using Monte Carlo simulations. Separate sets of base case model parameters were evaluated for the US and UK populations. MAIN OUTCOMES AND MEASURES: We assigned unitless health ""costs"" for each final state on a scale of 0 to 100. Population health ""costs"" were compared with the base case (status quo) assuming e-cigarette use health ""costs"" from 1% to 50% as dangerous as conventional cigarette use health costs. RESULTS: Compared with the base case, a harm reduction scenario in which e-cigarette use increases only among smokers who are interested in quitting with more quit attempts and no increased initiation of e-cigarette use among nonsmokers, and another scenario in which e-cigarettes are taken up only by youth who would have smoked conventional cigarettes, had population-level health benefits regardless of e-cigarette health costs in both the United States and United Kingdom. Conversely, scenarios in which e-cigarette promotion leads to renormalization of cigarette smoking or e-cigarettes are used primarily by youth who never would have smoked showed net health harms across all e-cigarette health costs. In other scenarios, the net health effect varied on the basis of the health cost of e-cigarettes. CONCLUSIONS AND RELEVANCE: According to this analysis, widespread promotion of e-cigarettes may have a wide range of population-level health effects, depending on both e-cigarette health risks and patterns of use. Absent the primary effect of e-cigarette promotion being only to divert current or future conventional cigarette smokers to e-cigarette use, the current uncertainty about the health risks of e-cigarettes, increasing e-cigarette use among youth, and the varying health effects at different e-cigarette health costs suggest a potential for harm.",2015-10,26/11/2018 12:51,14/04/2020 08:34,,1671-1680,,10,175,,JAMA Intern Med,,,,,,,,eng,,,,,,,PMID: 26322924 PMCID: PMC4594196,,,,Humans; Outcome Assessment (Health Care); Adult; Female; Male; Risk Assessment; Adolescent; Monte Carlo Method; United States/epidemiology; Prevalence; United Kingdom/epidemiology; Smoking Prevention; 00; *Electronic Nicotine Delivery Systems/adverse effects/economics/statistics & numerical data; *Smoking/adverse effects/economics/epidemiology; Marketing/methods; Population Surveillance; Smoking Cessation/methods/statistics & numerical data; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DGCSSSAJ,journalArticle,2015,"Wang, Xin; Sun, Yuanling; Mu, Xin; Guan, Li; Li, Jingjie",How to improve the equity of health financial sources? - Simulation and analysis of total health expenditure of one Chinese province on system dynamics.,International journal for equity in health,,1475-9276 1475-9276,10.1186/s12939-015-0203-x,,"INTRODUCTION: We simulate and analyze Total Health Expenditure (THE) in financial sources and other economic indicators (such as THE per capita, GDP, etc.) in a province of China from 2002 to 2012 on System Dynamics. METHODS: Based on actual data and certain mathematical methods, we use system dynamic software to construct a logic model for THE and changing proportions, and thus simulate the actual conditions of development and changes in THE. RESULTS: According to the simulation results, the government possess the largest investment in the average annual growth rate of THE, which was 25.16% in 2012. Social investment comprises the majority of the possession ratio, which was up to 41.20%. CONCLUSIONS: The personal investment growth rate decreased by almost 21%, but the total amount of personal investment increased by 28075 million yuan, which is far higher than the increase in government investment. Individuals are still the main carriers of health care expenses. The equity of health financial sources is still poor. The System Dynamics method used in this paper identifies a dynamic measurement process, provides a scientific basis for simulation and analysis of the changes in THE and its key constraining factors, as well as put forward suggestions for the improvement of equity of health financial sources.",27/08/2015,26/11/2018 12:51,14/04/2020 08:35,,73,,,14,,Int J Equity Health,,,,,,,,eng,,,,,,,PMID: 26306500 PMCID: PMC4549880,,,,"Humans; Models, Theoretical; China; Delivery of Health Care/*economics; Financing, Government/economics; Financing, Personal/economics; Gross Domestic Product; Health Expenditures/*trends; Software; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JTSR5546,journalArticle,2015,"Ward, Michael J.; Self, Wesley H.; Froehle, Craig M.",Effects of Common Data Errors in Electronic Health Records on Emergency Department Operational Performance Metrics: A Monte Carlo Simulation.,Academic emergency medicine : official journal of the Society for Academic Emergency Medicine,,1553-2712 1069-6563,10.1111/acem.12743,,"OBJECTIVES: The objective was to estimate how data errors in electronic health records (EHRs) can affect the accuracy of common emergency department (ED) operational performance metrics. METHODS: Using a 3-month, 7,348-visit data set of electronic time stamps from a suburban academic ED as a baseline, Monte Carlo simulation was used to introduce four types of data errors (substitution, missing, random, and systematic bias) at three frequency levels (2, 4, and 7%). Three commonly used ED operational metrics (arrival to clinician evaluation, disposition decision to exit for admitted patients, and ED length of stay for admitted patients) were calculated and the proportion of ED visits that achieved each performance goal was determined. RESULTS: Even small data errors have measurable effects on a clinical organization's ability to accurately determine whether it is meeting its operational performance goals. Systematic substitution errors, increased frequency of errors, and the use of shorter-duration metrics resulted in a lower proportion of ED visits reported as meeting the associated performance objectives. However, the presence of other error types mitigated somewhat the effect of the systematic substitution error. Longer time-duration metrics were found to be less sensitive to data errors than shorter time-duration metrics. CONCLUSIONS: Infrequent and small-magnitude data errors in EHR time stamps can compromise a clinical organization's ability to determine accurately if it is meeting performance goals. By understanding the types and frequencies of data errors in an organization's EHR, organizational leaders can use data management best practices to better measure true performance and enhance operational decision-making.",2015-09,26/11/2018 12:51,14/04/2020 08:35,,1085-1092,,9,22,,Acad Emerg Med,,,,,,,,eng,(c) 2015 by the Society for Academic Emergency Medicine.,,,,,,PMID: 26291051 PMCID: PMC4560638,,,,"Humans; Female; Male; *Monte Carlo Method; Hospitalization; Length of Stay; 1; Electronic Health Records/*standards; *Data Accuracy; Emergency Service, Hospital/*organization & administration/standards; Monte Carlo; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LXXBLUPE,journalArticle,2015,"Shultz, Cameron G.; Malouin, Jean M.; Green, Lee A.; Plegue, Melissa; Greenberg, Grant M.",A Systems Approach to Improving Tdap Immunization Within 5 Community-Based Family Practice Settings: Working Differently (and Better) by Transforming the Structure and Process of Care.,American journal of public health,,1541-0048 0090-0036,10.2105/AJPH.2015.302739,,"OBJECTIVES: We examined how family medicine clinic physicians and staff worked in collaborative teams to implement an automated clinical reminder to improve tetanus, diphtheria, and acellular pertussis (Tdap) booster vaccine administration and documentation. METHODS: A clinical reminder was developed at 5 University of Michigan family medicine clinics to identify patients 11 to 64 years old who were in need of the Tdap booster vaccine. Quality improvement cycles were used to improve clinic care processes. Immunization rates from 2008 to 2011 were compared with rates at 4 primary care control clinics. RESULTS: Vaccination rates among eligible patients increased from 15.5% to 47.3% within the family medicine clinics and from 14.1% to 30.2% within the control clinics. After adjustment for covariates, family medicine patients had a higher probability of vaccination than control patients during each measurement period (0.17 vs 0.15 at baseline, 0.53 vs 0.22 during year 1, and 0.50 vs 0.30 during year 2). CONCLUSIONS: Automated clinical reminders, when designed and implemented via a consensus-based framework that addresses the process of care, can dramatically improve provision of preventive health care.",2015-10,26/11/2018 12:51,14/04/2020 08:35,,1990-1997,,10,105,,Am J Public Health,,,,,,,,eng,,,,,,,PMID: 26270283 PMCID: PMC4566568,,,,Humans; Health Services Research; Adult; Female; Male; Middle Aged; Child; Adolescent; Community Health Services/*organization & administration; Michigan; 00; *Outcome and Process Assessment (Health Care); *Reminder Systems; Diphtheria-Tetanus-acellular Pertussis Vaccines/*administration & dosage; Family Practice/*organization & administration; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5J9RCPYE,journalArticle,2017,"Ribesse, Nathalie; Bossyns, Paul; Marchal, Bruno; Karemere, Hermes; Burman, Christopher J.; Macq, Jean",Methodological approach and tools for systems thinking in health systems research: technical assistants' support of health administration reform in the Democratic Republic of Congo as an application.,Global health promotion,,1757-9767 1757-9759,10.1177/1757975915591684,,"In the field of development cooperation, interest in systems thinking and complex systems theories as a methodological approach is increasingly recognised. And so it is in health systems research, which informs health development aid interventions. However, practical applications remain scarce to date. The objective of this article is to contribute to the body of knowledge by presenting the tools inspired by systems thinking and complexity theories and methodological lessons learned from their application. These tools were used in a case study. Detailed results of this study are in process for publication in additional articles. Applying a complexity 'lens', the subject of the case study is the role of long-term international technical assistance in supporting health administration reform at the provincial level in the Democratic Republic of Congo. The Methods section presents the guiding principles of systems thinking and complex systems, their relevance and implication for the subject under study, and the existing tools associated with those theories which inspired us in the design of the data collection and analysis process. The tools and their application processes are presented in the results section, and followed in the discussion section by the critical analysis of their innovative potential and emergent challenges. The overall methodology provides a coherent whole, each tool bringing a different and complementary perspective on the system.",2017-03,26/11/2018 12:51,14/04/2020 08:35,,43-52,,1,24,,Glob Health Promot,,,,,,,,eng,,,,,,,PMID: 26260471,,,,Delivery of Health Care/*organization & administration; Humans; Systems Analysis; public health; Organizational Innovation; Government Programs; 00; Democratic Republic of the Congo; Health Care Reform/*organization & administration; Health Planning Technical Assistance/organization & administration; organizational development/organisational change; policy/politics; systems; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, D3MW3ZWG,journalArticle,2015,"Atkinson, Jo-An M.; Wells, Robert; Page, Andrew; Dominello, Amanda; Haines, Mary; Wilson, Andrew",Applications of system dynamics modelling to support health policy.,Public health research & practice,,2204-2091 2204-2091,10.17061/phrp2531531,,"INTRODUCTION: The value of systems science modelling methods in the health sector is increasingly being recognised. Of particular promise is the potential of these methods to improve operational aspects of healthcare capacity and delivery, analyse policy options for health system reform and guide investments to address complex public health problems. Because it lends itself to a participatory approach, system dynamics modelling has been a particularly appealing method that aims to align stakeholder understanding of the underlying causes of a problem and achieve consensus for action. The aim of this review is to determine the effectiveness of system dynamics modelling for health policy, and explore the range and nature of its application. METHOD: A systematic search was conducted to identify articles published up to April 2015 from the PubMed, Web of Knowledge, Embase, ScienceDirect and Google Scholar databases. The grey literature was also searched. Papers eligible for inclusion were those that described applications of system dynamics modelling to support health policy at any level of government. RESULTS AND DISCUSSION: Six papers were identified, comprising eight case studies of the application of system dynamics modelling to support health policy. No analytic studies were found that examined the effectiveness of this type of modelling. Only three examples engaged multidisciplinary stakeholders in collective model building. Stakeholder participation in model building reportedly facilitated development of a common 'mental map' of the health problem, resulting in consensus about optimal policy strategy and garnering support for collaborative action. The paucity of relevant papers indicates that, although the volume of descriptive literature advocating the value of system dynamics modelling is considerable, its practical application to inform health policy making is yet to be routinely applied and rigorously evaluated. CONCLUSION: Advances in software are allowing the participatory model building approach to be extended to more sophisticated multimethod modelling that provides policy makers with more powerful tools to support the design of targeted, effective and equitable policy responses for complex health problems. Building capacity and investing in communication to promote these modelling methods, as well as documenting and evaluating their applications, will be vital to supporting uptake by policy makers.",09/07/2015,26/11/2018 12:51,14/04/2020 08:34,,e2531531,,3,25,,Public Health Res Pract,,,,,,,,eng,,,,,,,PMID: 26243490,,,,"*Health Policy; Humans; Models, Theoretical; Australia; System dynamics; Public Health Administration/*methods; *Policy Making; 1; 210",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MCJQ5MXZ,journalArticle,2015,"Javanbakht, Mehdi; Mashayekhi, Atefeh; Baradaran, Hamid R.; Haghdoost, AliAkbar; Afshin, Ashkan",Projection of Diabetes Population Size and Associated Economic Burden through 2030 in Iran: Evidence from Micro-Simulation Markov Model and Bayesian Meta-Analysis.,PloS one,,1932-6203 1932-6203,10.1371/journal.pone.0132505,,"BACKGROUND: The aim of this study was to estimate the economic burden of diabetes mellitus (DM) in Iran from 2009 to 2030. METHODS: A Markov micro-simulation (MM) model was developed to predict the DM population size and associated economic burden. Age- and sex-specific prevalence and incidence of diagnosed and undiagnosed DM were derived from national health surveys. A systematic review was performed to identify the cost of diabetes in Iran and the mean annual direct and indirect costs of patients with DM were estimated using a random-effect Bayesian meta-analysis. Face, internal, cross and predictive validity of the MM model were assessed by consulting an expert group, performing sensitivity analysis (SA) and comparing model results with published literature and national survey reports. Sensitivity analysis was also performed to explore the effect of uncertainty in the model. RESULTS: We estimated 3.78 million cases of DM (2.74 million diagnosed and 1.04 million undiagnosed) in Iran in 2009. This number is expected to rise to 9.24 million cases (6.73 million diagnosed and 2.50 million undiagnosed) by 2030. The mean annual direct and indirect costs of patients with DM in 2009 were US$ 556 (posterior standard deviation, 221) and US$ 689 (619), respectively. Total estimated annual cost of DM was $3.64 (2009 US$) billion (including US$1.71 billion direct and US$1.93 billion indirect costs) in 2009 and is predicted to increase to $9.0 (in 2009 US$) billion (including US$4.2 billion direct and US$4.8 billion indirect costs) by 2030. CONCLUSIONS: The economic burden of DM in Iran is predicted to increase markedly in the coming decades. Identification and implementation of effective strategies to prevent and manage DM should be considered as a public health priority.",2015,26/11/2018 12:51,14/04/2020 08:34,,e0132505,,7,10,,PLoS One,,,,,,,,eng,,,,,,,PMID: 26200913 PMCID: PMC4511591,,,,"Humans; Markov Chains; Bayes Theorem; Incidence; Models, Econometric; Prevalence; Health Surveys; *Cost of Illness; Iran/epidemiology; 00; Diabetes Mellitus/*economics/*epidemiology; Health Care Costs/trends; Review",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 974EL6MC,journalArticle,2015,"Pinelli, Vincent A.; Papp, Klara K.; Gonzalo, Jed D.",Interprofessional Communication Patterns During Patient Discharges: A Social Network Analysis.,Journal of general internal medicine,,1525-1497 0884-8734,10.1007/s11606-015-3415-2,,"BACKGROUND: Optimal care delivery requires timely, efficient, and accurate communication among numerous providers and their patients, especially during hospital discharge. Little is known about communication patterns during this process. OBJECTIVE: Our aim was to assess the frequency and patterns of communication between patients and providers during patient discharges from a hospital-based medicine unit. DESIGN AND APPROACH: On the day of the patient's discharge, the patient and all healthcare providers involved in the discharge were interviewed using structured questions related to information exchange during the discharge process. Each interview identified the frequency and method of communication between participants, including synchronous (e.g., face-to-face) and asynchronous (e.g., through electronic medical record) routes. Communication patterns were visually diagramed using social network analysis. PARTICIPANTS: Forty-six patients were screened for inclusion in the network analysis. Of those, seven patients who were fully oriented and able to complete an interview and all providers who participated in their care during the discharge were selected for inclusion in the analysis. In all, 72 healthcare professionals contributing to the discharge process were interviewed, including physicians, nurses, therapists, pharmacists, care coordinators, social workers, and nutritionists. KEY RESULTS: Patients' mean age was 63, length-of-stay was 7.8 days, and most (86 %) were discharged to home. On average, 11 roles were involved with each discharge. The majority of communication was synchronous (562 events vs. 469 asynchronous events, p = 0.004). Most communication events occurred between the primary nurse and patient and the care coordinator and primary nurse (mean 3.9 and 2.3 events/discharge, respectively). Participants identified intern physicians as most important in the discharge process, followed by primary nurses and care coordinators. CONCLUSIONS: In patients being discharged from the medicine service, communication was more frequently synchronous, and occurred between intern physicians, primary nurses, and patients. Potential improvements in coordinating patients' discharges are possible by reorganizing systems to optimize efficient communication.",2015-09,26/11/2018 12:51,14/04/2020 08:35,,1299-1306,,9,30,,J Gen Intern Med,,,,,,,,eng,,,,,,,PMID: 26173532 PMCID: PMC4539328,,,,"Humans; Female; Male; Middle Aged; Patient Care Team/organization & administration; Hospitals, University; *Social Support; Interviews as Topic; *Interdisciplinary Communication; Length of Stay/statistics & numerical data; *Patient Discharge; 00; Internal Medicine; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HTXWDM96,journalArticle,2015,"Bae, Sung-Heui; Nikolaev, Alexander; Seo, Jin Young; Castner, Jessica",Health care provider social network analysis: A systematic review.,Nursing outlook,,1528-3968 0029-6554,10.1016/j.outlook.2015.05.006,,"OBJECTIVES: Although considerable progress has been made in understanding networks, their structure, and their development, little has been known about their effectiveness in the health care setting and their contributions to quality of care and patient safety.The purpose of this study was to examine studies using social network analysis (SNA) in the health care workforce and assess factors contributing to social network and their relationships with care processes and patient outcomes. METHODS: We identified all published peer-reviewed SNA articles in CINAHL, PubMed, PsycINFO, JSTOR, Medline (OVID), and Web of Science databases up to April 2013. RESULTS: Twenty-nine published articles met the inclusion criteria. Current evidence of the health care workforce's social networks reveals the nature of social ties are related to personal characteristics, practice setting, and types of patients. A few studies also revealed the social network effects adoption and the use of a health information system, patient outcomes, and coordination. CONCLUSIONS: Current studies on the social ties of health care workforce professionals include several assessments of inefficiencies. The level of technical sophistication in these studies tended to be low. Future study using enhanced sophistication in study design, analysis, and patient outcome testing are warranted to fully leverage the potential of SNA in health care studies.",2015-10,26/11/2018 12:51,14/04/2020 08:34,,566-584,,5,63,,Nurs Outlook,,,,,,,,eng,Copyright (c) 2015 Elsevier Inc. All rights reserved.,,,,,,PMID: 26162750,,,,Delivery of Health Care/*organization & administration; Humans; Outcome and Process Assessment (Health Care); Patient Safety; *Social Networking; Social network analysis; 00; Care process; Health care provider; Health Personnel/*organization & administration; Patient outcomes; Systematic review; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WBRJ84DB,journalArticle,2016,"Gold, Jeffrey Allen; Stephenson, Laurel E.; Gorsuch, Adriel; Parthasarathy, Keshav; Mohan, Vishnu",Feasibility of utilizing a commercial eye tracker to assess electronic health record use during patient simulation.,Health informatics journal,,1741-2811 1460-4582,10.1177/1460458215590250,,"Numerous reports describe unintended consequences of electronic health record implementation. Having previously described physicians' failures to recognize patient safety issues within our electronic health record simulation environment, we now report on our use of eye and screen-tracking technology to understand factors associated with poor error recognition during an intensive care unit-based electronic health record simulation. We linked performance on the simulation to standard eye and screen-tracking readouts including number of fixations, saccades, mouse clicks and screens visited. In addition, we developed an overall Composite Eye Tracking score which measured when, where and how often each safety item was viewed. For 39 participants, the Composite Eye Tracking score correlated with performance on the simulation (p = 0.004). Overall, the improved performance was associated with a pattern of rapid scanning of data manifested by increased number of screens visited (p = 0.001), mouse clicks (p = 0.03) and saccades (p = 0.004). Eye tracking can be successfully integrated into electronic health record-based simulation and provides a surrogate measure of cognitive decision making and electronic health record usability.",2016-09,26/11/2018 12:51,14/04/2020 08:34,,744-757,,3,22,,Health Informatics J,,,,,,,,eng,(c) The Author(s) 2015.,,,,,,PMID: 26142432,,,,Humans; *Patient Simulation; Feasibility Studies; Clinical Decision-Making/*methods; Intensive Care Units; 00; *clinical decision making; *electronic health records; *healthcare professional training; *healthcare service innovation and IT; *IT healthcare evaluation; *Saccades; Electronic Health Records/*utilization; Physicians/psychology; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NR9TDISF,journalArticle,2015,"Skouteris, Helen; Huang, Terry; Millar, Lynne; Kuhlberg, Jill; Dodd, Jodie; Callaway, Leonie; Forster, Della; Collins, Clare; Hills, Andrew; Harrison, Paul; Nagle, Cate; Moodie, Marj; Teede, Helena","A systems approach to reducing maternal obesity: The Health in Preconception, Pregnancy and Postbirth (HIPPP) Collaborative.",The Australian & New Zealand journal of obstetrics & gynaecology,,1479-828X 0004-8666,10.1111/ajo.12341,,"Obesity in our childbearing population has increased to epidemic proportions in developed countries; efforts to address this issue need to focus on prevention. The Health in Preconception, Pregnancy and Postbirth (HIPPP) Collaborative - a group of researchers, practitioners, policymakers and end-users - was formed to take up the challenge to address this issue as a partnership. Application of systems thinking, participatory systems modelling and group model building was used to establish research questions aiming to optimise periconception lifestyle, weight and health. Our goal was to reduce the burden of maternal obesity through systems change.",2015-08,26/11/2018 12:51,14/04/2020 08:35,,397-400,,4,55,,Aust N Z J Obstet Gynaecol,,,,,,,,eng,(c) 2015 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists.,,,,,,PMID: 26121995,,,,"Humans; Health Policy; Female; *Systems Analysis; Pregnancy; Models, Theoretical; Australia; Interdisciplinary Communication; Cooperative Behavior; 00; *Maternal Health Services; gestational weight gain; Health Promotion/*methods/organization & administration; maternal obesity; Obesity/*prevention & control; preconception; pregnancy; Pregnancy Complications/*prevention & control; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RQUU54ZG,journalArticle,2016,"Pitt, Martin; Monks, Thomas; Crowe, Sonya; Vasilakis, Christos","Systems modelling and simulation in health service design, delivery and decision making.",BMJ quality & safety,,2044-5423 2044-5415,10.1136/bmjqs-2015-004430,,"The ever increasing pressures to ensure the most efficient and effective use of limited health service resources will, over time, encourage policy makers to turn to system modelling solutions. Such techniques have been available for decades, but despite ample research which demonstrates potential, their application in health services to date is limited. This article surveys the breadth of approaches available to support delivery and design across many areas and levels of healthcare planning. A case study in emergency stroke care is presented as an exemplar of an impactful application of health system modelling. This is followed by a discussion of the key issues surrounding the application of these methods in health, what barriers need to be overcome to ensure more effective implementation, as well as likely developments in the future.",2016-01,26/11/2018 12:51,14/04/2020 08:35,,38-45,,1,25,,BMJ Qual Saf,,,,,,,,eng,Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/,,,,,,PMID: 26115667,,,,"Delivery of Health Care/*organization & administration; Humans; Health Policy; *Computer Simulation; *Efficiency, Organizational; *Models, Theoretical; Healthcare quality improvement; Quality improvement methodologies; Operations Research; *Decision Making; 1; Capacity Building/organization & administration; Emergency Service, Hospital/organization & administration; Quality improvement; Stroke/drug therapy; Thrombolytic Therapy/methods; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TL6BQAQP,journalArticle,2016,"Mohamed-Ahmed, Rayan; Daniels, Alex; Goodall, Jack; O'Kelly, Emily; Fisher, James",'Disaster day': global health simulation teaching.,The clinical teacher,,1743-498X 1743-4971,10.1111/tct.12349,,"BACKGROUND: As society diversifies and globalisation quickens, the importance of teaching global health to medical undergraduates increases. For undergraduates, the majority of exposure to 'hands-on' teaching on global health occurs during optional elective periods. This article describes an innovative student-led initiative, 'Disaster Day', which used simulation to teach global health to undergraduates. METHODS: The teaching day began with an introduction outlining the work of Medecins Sans Frontieres and the basic principles of resuscitation. Students then undertook four interactive simulation scenarios: Infectious Diseases in a Refugee Camp, Natural Disaster and Crush Injury, Obstetric Emergency in a Low-Income Country, and Warzone Gunshot Wound. Sessions were facilitated by experienced doctors and fourth-year students who had been trained in the delivery of the scenarios. Students completed pre- and post-session evaluation forms that included the self-rating of confidence in eight learning domains (using a five-point Likert scale). RESULTS: Twenty-seven students voluntarily attended the session, and all provided written feedback. Analysis of the pre- and post-session evaluations demonstrated statistically significant improvements in confidence across all but one domains (Wilcoxon signed rank test). Free-text feedback was overwhelmingly positive, with students appreciating the practical aspect of the scenarios. For undergraduates, the majority of exposure to 'hands-on' teaching on global health occurs during optional elective periods DISCUSSION: Simulation-based teaching can provide students with 'hands-on' exposure to global health in a controlled, reproducible fashion and appears to help develop their confidence in a variety of learning domains. The more widespread use of such teaching methods is encouraged: helping tomorrow's doctors develop insight into global health challenges may produce more rounded clinicians capable of caring for more culturally diverse populations.",2016-02,26/11/2018 12:51,14/04/2020 08:34,,18-22,,1,13,,Clin Teach,,,,,,,,eng,(c) 2015 John Wiley & Sons Ltd.,,,,,,PMID: 26110794,,,,"Humans; *Global Health; *Clinical Competence; Epidemics; Patient Simulation; Disaster Planning/*organization & administration; 00; Disasters; Education, Medical, Undergraduate/*organization & administration; Warfare; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7MH77VAA,journalArticle,2015,"Pringle, K.; Mackey, J. M.; Modi, P.; Janeway, H.; Romero, T.; Meynard, F.; Perez, H.; Herrera, R.; Bendana, M.; Labora, A.; Ruskis, J.; Foggle, J.; Partridge, R.; Levine, A. C.","""A short trauma course for physicians in a resource-limited setting: Is low-cost simulation effective?"".",Injury,,1879-0267 0020-1383,10.1016/j.injury.2015.05.021,,"INTRODUCTION: Morbidity and mortality from intentional and unintentional injury accounts for a high burden of disease in low- and middle-income countries. In addition to prevention measures, interventions that increase healthcare capacity to manage injuries may be an effective way to decrease morbidity and mortality. A trauma curriculum tailored to low-resource settings was implemented in Managua, Nicaragua utilising traditional didactic methods and novel low-cost simulation methods. Knowledge gain in attending and senior residents was subsequently assessed by using pre- and post-written tests, and by scoring pre- and post-simulation scenarios. MATERIALS AND METHODS: A 5-day trauma course was designed for Nicaraguan attending and senior resident physicians who practice at six hospitals in Managua, Nicaragua. On days 1 and 5, participants underwent pre- and post-training evaluations consisting of a 26-question written exam and 2 simulation cases. The written exam questions and simulations were randomly assigned so that no questions or cases were repeated. The Wilcoxon signed-rank test was used to compare pre- and post-training differences in the written exam, and the percentage of critical actions completed in simulations. Time to critical actions was also analyzed using descriptive statistics. RESULTS: A total of 33 participants attended the course, including 18 (55%) attending and 15 (45%) resident physicians, with a 97% completion rate. After the course, overall written examination scores improved 26.3% with positive mean increase of 15.4% (p<0.001). Overall, simulation scores based on the number of critical actions completed improved by 91.4% with a positive mean increase of 33.67 (p<0.001). The time to critical action for completion of the primary survey and cervical spine immobilisation was reduced by 55.9% and 46.6% respectively. CONCLUSIONS: A considerable improvement in participants' knowledge of trauma concepts was demonstrated by statistically significant differences in both pre- and post-course written assessments and simulation exercises. The participants showed greatest improvement in trauma simulation scenarios, in which they learned, and subsequently demonstrated, a standardised approach to assessing and managing trauma patients. Low-cost simulation can be a valuable and effective education tool in low- and middle-income countries.",2015-09,26/11/2018 12:51,14/04/2020 08:35,,1796-1800,,9,46,,Injury,,,,,,,,eng,Copyright (c) 2015 Elsevier Ltd. All rights reserved.,,,,,,PMID: 26073743,,,,"Humans; Program Evaluation; Cost-Benefit Analysis; Health Knowledge, Attitudes, Practice; Simulation; Physicians; 00; Medical education; Trauma; Clinical Competence/economics/*standards; Education, Medical, Continuing/economics/*standards; Emergency Medicine/economics/*education; Global emergency medicine; Nicaragua; Nicaragua/epidemiology; Wounds and Injuries/*therapy; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BUUY8UE6,journalArticle,2015,"Yu, Tzy-Chyi; Zhou, Huanxue",Benefits of applying a proxy eligibility period when using electronic health records for outcomes research: a simulation study.,BMC research notes,,1756-0500 1756-0500,10.1186/s13104-015-1217-6,,"BACKGROUND: Electronic health records (EHRs) can provide valuable data for outcomes research. However, unlike administrative claims databases, EHRs lack eligibility tables or a standard way to define the benefit coverage period, which could lead to underreporting of healthcare utilization or outcomes, and could result in surveillance bias. We tested the effect of using a proxy eligibility period (eligibility proxy) when estimating a range of health resource utilization and outcomes parameters under varying degrees of missing encounter data. METHODS: We applied an eligibility proxy to create a benchmark cohort of chronic obstructive pulmonary disease (COPD) patients with 12 months of follow-up, with the assumption of no missing encounter data. The benchmark cohort provided parameter estimates for comparison with 9,000 simulated datasets representing",09/06/2015,26/11/2018 12:51,14/04/2020 08:35,,229,,,8,,BMC Res Notes,,,,,,,,eng,,,,,,,PMID: 26055181 PMCID: PMC4467672,,,,"Humans; Health Services Research; Treatment Outcome; *Computer Simulation; Models, Statistical; Time Factors; Bias; *Electronic Health Records/statistics & numerical data; *Eligibility Determination/statistics & numerical data; *Insurance Coverage/statistics & numerical data; *Insurance, Health/statistics & numerical data; *Process Assessment (Health Care)/statistics & numerical data; Pulmonary Disease, Chronic Obstructive/diagnosis/*therapy; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WEWBAQTM,journalArticle,2017,"Mutale, Wilbroad; Ayles, Helen; Bond, Virginia; Chintu, Namwinga; Chilengi, Roma; Mwanamwenge, Margaret Tembo; Taylor, Angela; Spicer, Neil; Balabanova, Dina",Application of systems thinking: 12-month postintervention evaluation of a complex health system intervention in Zambia: the case of the BHOMA.,Journal of evaluation in clinical practice,,1365-2753 1356-1294,10.1111/jep.12354,,"RATIONALE, AIMS AND OBJECTIVES: Strong health systems are said to be paramount to achieving effective and equitable health care. The World Health Organization has been advocating for using system-wide approaches such as 'systems thinking' to guide intervention design and evaluation. In this paper we report the system-wide effects of a complex health system intervention in Zambia known as Better Health Outcome through Mentorship and Assessment (BHOMA) that aimed to improve service quality. METHODS: We conducted a qualitative study in three target districts. We used a systems thinking conceptual framework to guide the analysis focusing on intended and unintended consequences of the intervention. NVivo version 10 was used for data analysis. RESULTS: The addressed community responded positively to the BHOMA intervention. The indications were that in the short term there was increased demand for services but the health worker capacity was not severely affected. This means that the prediction that service demand would increase with implementation of BHOMA was correct and the workload also increased, but the help of clinic lay supporters meant that some of the work of clinicians was transferred to these lay workers. However, from a systems perspective, unintended consequences also occurred during the implementation of the BHOMA. CONCLUSIONS: We applied an innovative approach to evaluate a complex intervention in low-income settings, exploring empirically how systems thinking can be applied in the context of health system strengthening. Although the intervention had some positive outcomes by employing system-wide approaches, we also noted unintended consequences.",2017-04,26/11/2018 12:51,14/04/2020 08:35,,439-452,,2,23,,J Eval Clin Pract,,,,,,,,eng,"(c) 2015 The Authors. Journal of Evaluation in Clinical Practice published by John Wiley & Sons, Ltd.",,,,,,PMID: 26011652,,,,"Humans; Qualitative Research; *Systems Analysis; health policy; Health Knowledge, Attitudes, Practice; Inservice Training; Health Services Needs and Demand; 00; Poverty; Zambia; Community Health Workers/education/*organization & administration; Community Participation/methods; Delivery of Health Care/*organization & administration/standards; evaluation; health services research; HIV Infections/diagnosis/therapy; Medical Records/standards; Quality Improvement/*organization & administration/standards; Referral and Consultation/organization & administration; Triage/standards; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 658UDYTI,journalArticle,2015,"Spolverato, Gaya; Vitale, Alessandro; Ejaz, Aslam; Kim, Yuhree; Cosgrove, David; Schlacter, Todd; Geschwind, Jean-Francis; Pawlik, Timothy M.",Net health benefit of hepatic resection versus intraarterial therapies for neuroendocrine liver metastases: A Markov decision model.,Surgery,,1532-7361 0039-6060,10.1016/j.surg.2015.03.033,,"BACKGROUND: Management of patients with neuroendocrine liver metastasis (NELM) remains controversial. We sought to compare the net health benefit (NHB) of hepatic resection (HR) versus intraarterial therapy (IAT) among patients with NELM. METHODS: A decision analytic Markov model was created to estimate and compare the cost effectiveness associated with different management strategies (HR vs IAT) for a simulated cohort of patients with NELM. The primary (base case) analysis was calculated based on a 57-year-old male patient with metachronous, symptomatic NELM that involved <25% of the liver in the absence of extrahepatic disease. The endpoints were quality-adjusted life-months (QALMs), quality-adjusted life-year (QALY), incremental cost-effectiveness ratio (ICER), and NHB. RESULTS: In the base case analysis, HR was strongly favored over IAT providing NHB of 20.0 QALMs and an ICER of $8,427 per QALY. In the Monte Carlo simulation, the greatest NHB for HR was among patients with functioning/symptomatic NELM, regardless of liver tumor burden. In the symptomatic group, IAT was favored only in a minority of old patients (>60 years) with extrahepatic disease and synchronous NELM. In contrast, in patients with nonfunctioning/asymptomatic NELM, hepatic tumor burden was the most important variable and HR was always cost ineffective in large tumors, independent of patient age and extrahepatic disease characteristics. CONCLUSION: A Markov decision model demonstrated that HR was the preferred strategy among patients with symptomatic NELM, regardless of hepatic disease burden. In contrast, IAT should be preferred for patients with large volume nonfunctioning/asymptomatic NELM.",2015-08,26/11/2018 12:51,14/04/2020 08:35,,339-348,,2,158,,Surgery,,,,,,,,eng,Copyright (c) 2015 Elsevier Inc. All rights reserved.,,,,,,PMID: 25999251,,,,"Humans; United States; Quality-Adjusted Life Years; Treatment Outcome; Health Care Costs; Male; Middle Aged; *Cost-Benefit Analysis; Markov Chains; Decision Support Techniques; Monte Carlo Method; Computer Simulation; Models, Economic; 00; Hepatectomy/*economics/mortality; Infusions, Intra-Arterial/*economics/mortality; Liver Neoplasms/economics/mortality/*secondary/*therapy; Neuroendocrine Tumors/economics/mortality/*secondary/*therapy; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UHR6MJ4F,journalArticle,2016,"Basu, Sanjay; Kiernan, Michaela",A Simulation Modeling Framework to Optimize Programs Using Financial Incentives to Motivate Health Behavior Change.,Medical decision making : an international journal of the Society for Medical Decision Making,,1552-681X 0272-989X,10.1177/0272989X15585984,,"INTRODUCTION: While increasingly popular among mid- to large-size employers, using financial incentives to induce health behavior change among employees has been controversial, in part due to poor quality and generalizability of studies to date. Thus, fundamental questions have been left unanswered: To generate positive economic returns on investment, what level of incentive should be offered for any given type of incentive program and among which employees? METHODS: We constructed a novel modeling framework that systematically identifies how to optimize marginal return on investment from programs incentivizing behavior change by integrating commonly collected data on health behaviors and associated costs. We integrated ""demand curves"" capturing individual differences in response to any given incentive with employee demographic and risk factor data. We also estimated the degree of self-selection that could be tolerated: that is, the maximum percentage of already-healthy employees who could enroll in a wellness program while still maintaining positive absolute return on investment. In a demonstration analysis, the modeling framework was applied to data from 3000 worksite physical activity programs across the nation. RESULTS: For physical activity programs, the incentive levels that would optimize marginal return on investment ($367/employee/year) were higher than average incentive levels currently offered ($143/employee/year). Yet a high degree of self-selection could undermine the economic benefits of the program; if more than 17% of participants came from the top 10% of the physical activity distribution, the cost of the program would be expected to always be greater than its benefits. DISCUSSION: Our generalizable framework integrates individual differences in behavior and risk to systematically estimate the incentive level that optimizes marginal return on investment.",2016-01,26/11/2018 12:51,14/04/2020 08:34,,48-58,,1,36,,Med Decis Making,,,,,,,,eng,(c) The Author(s) 2015.,,,,,,PMID: 25977362 PMCID: PMC4801226,,,,"Humans; Socioeconomic Factors; Risk Factors; *Computer Simulation; Decision Making; Models, Econometric; Exercise; *Workplace; *Health Behavior; *Motivation; Stochastic Processes; 1; Occupational Health; *behavior change; *financial incentives; *mathematical model; *physical activity; *workplace wellness programs; Health Promotion/economics/*organization & administration; 420",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RJEBS49F,journalArticle,2015,"Franco, Zeno E.; Ahmed, Syed M.; Maurana, Cheryl A.; DeFino, Mia C.; Brewer, Devon D.",A Social Network Analysis of 140 Community-Academic Partnerships for Health: Examining the Healthier Wisconsin Partnership Program.,Clinical and translational science,,1752-8062 1752-8054,10.1111/cts.12288,,"INTRODUCTION: Social Network Analysis (SNA) provides an important, underutilized approach to evaluating Community Academic Partnerships for Health (CAPHs). This study examines administrative data from 140 CAPHs funded by the Healthier Wisconsin Partnership Program (HWPP). METHODS: Funder data was normalized to maximize number of interconnections between funded projects and 318 non-redundant community partner organizations in a dual mode analysis, examining the period from 2003-2013.Two strategic planning periods, 2003-2008 vs. 2009-2014, allowed temporal comparison. RESULTS: Connectivity of the network was largely unchanged over time, with most projects and partner organizations connected to a single large component in both time periods. Inter-partner ties formed in HWPP projects were transient. Most community partners were only involved in projects during one strategic time period. Community organizations participating in both time periods were involved in significantly more projects during the first time period than partners participating in the first time period only (Cohen's d = 0.93). DISCUSSION: This approach represents a significant step toward using objective (non-survey) data for large clusters of health partnerships and has implications for translational science in community settings. Considerations for government, funders, and communities are offered. Examining partnerships within health priority areas, orphaned projects, and faculty ties to these networks are areas for future research.",2015-08,26/11/2018 12:51,14/04/2020 08:34,,311-319,,4,8,,Clin Transl Sci,,,,,,,,eng,"(c) 2015 Wiley Periodicals, Inc.",,,,,,PMID: 25974413 PMCID: PMC4977991,,,,Humans; Time Factors; *Cooperative Behavior; *Social Support; social network analysis; Wisconsin; 1; *Community-Institutional Relations; community engagement; community-academic partnerships for health; team science; translational research; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, A3T9TYQI,journalArticle,2015,"Tozan, Yesim; Ompad, Danielle C.",Complexity and dynamism from an urban health perspective: a rationale for a system dynamics approach.,Journal of urban health : bulletin of the New York Academy of Medicine,,1468-2869 1099-3460,10.1007/s11524-015-9963-2,,"In a variety of urban health frameworks, cities are conceptualized as complex and dynamic yet commonly used epidemiological methods have failed to address this complexity and dynamism head on due to their narrow problem definitions and linear analytical representations. Scholars from a variety of disciplines have also long conceptualized cities as systems, but few have modeled urban health issues as problems within a system. Systems thinking in general and system dynamics in particular are relatively new approaches in public health, but ones that hold immense promise as methodologies to model and analyze the complexity underlying urban processes to effectively inform policy actions in dynamic environments. This conceptual essay reviews the utility of applying the concepts, principles, and methods of systems thinking to the study of complex urban health phenomena as a complementary approach to standard epidemiological methods using specific examples and provides recommendations on how to better incorporate systems thinking methods in urban health research and practice.",2015-06,26/11/2018 12:51,14/04/2020 08:34,,490-501,,3,92,,J Urban Health,,,,,,,,eng,,,,,,,PMID: 25952137 PMCID: PMC4456484,,,,"Humans; Systems Analysis; Models, Theoretical; System dynamics; System Dynamics; 1; Cities/epidemiology; *Urban Health/statistics & numerical data; Ontario/epidemiology; Social Determinants of Health/statistics & numerical data; 310",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UFQ86KBL,journalArticle,2015,"Luctkar-Flude, Marian; Tyerman, Jane; Wilson-Keates, Barbara; Pulling, Cheryl; Larocque, Monica; Yorke, Jessica",Introduction of unresponsive patient simulation scenarios into an undergraduate nursing health assessment course.,The Journal of nursing education,,1938-2421 0148-4834,10.3928/01484834-20150417-06,,"BACKGROUND: Despite certification in basic life support, nursing students may not be proficient in performing critical assessments and interventions for unresponsive patients. Thus, a new simulation module comprising four unresponsive patient scenarios was introduced into a second-year nursing health assessment course. METHOD: This cross-sectional study describes nursing student experience, knowledge, confidence, and performance of assessments and interventions for the unresponsive patient across 3 years of an undergraduate nursing program. RESULTS: Overall knowledge, confidence, and performance scores were similar between second-, third-, and fourth-year students (N = 239); however, performance times for many critical assessments and interventions were poor. Second-year nursing students' knowledge increased significantly following the new simulation module (p = 0.002). CONCLUSION: Findings suggest a need for more repetition of basic unresponsive patient scenarios to provide mastery. It is anticipated that addition of unresponsive patient scenarios into the second year will enhance performance by the final year of the program.",2015-05,26/11/2018 12:51,14/04/2020 08:34,,281-285,,5,54,,J Nurs Educ,,,,,,,,eng,"Copyright 2015, SLACK Incorporated.",,,,,,PMID: 25950364,,,,"Humans; *Simulation Training; Clinical Competence; Female; Male; Young Adult; Cross-Sectional Studies; *Education, Nursing, Baccalaureate; *Problem-Based Learning; Self Concept; 00; *Nursing Assessment; Unconsciousness/*nursing; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ID36LHCG,journalArticle,2015,"Jacobs, Carmel; Hutton, Brian; Mazzarello, Sasha; Smith, Stephanie; Joy, Anil; Amir, Eitan; Ibrahim, Mohammed F. K.; Gregario, Nancy; Daigle, Kelly; Eggert, Lori; Clemons, Mark",Optimisation of steroid prophylaxis schedules in breast cancer patients receiving docetaxel chemotherapy-a survey of health care providers and patients.,Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer,,1433-7339 0941-4355,10.1007/s00520-015-2731-8,,"PURPOSE: Despite the widespread use of steroid prophylaxis schedules for breast cancer patients receiving docetaxel chemotherapy, questions still exist regarding their optimal use. We surveyed health care providers and patients about their experiences with steroid prophylaxis. METHODS: Two questionnaires were developed and circulated. One was presented to health care providers (chemotherapy nurses, pharmacists and medical oncologists) involved in the treatment of breast cancer and the second to patients who had received docetaxel chemotherapy for early stage breast cancer. RESULTS: The health care providers' questionnaire was completed by 184 of 698 invitees: 92/171 (53.8 %) chemotherapy nurses, 56/284 (19.7 %) pharmacists and 36/243 (14.8 %) medical oncologists (overall response rate 26.4 %). Two steroid schedules were found to be the most commonly used: dexamethasone 8 mg BID for 6 doses, with either 3 (79 %) or 2 (11 %) doses taken before docetaxel administration. Suboptimal adherence to steroid premedication had been experienced by 98 % (177/181) of practitioners. Despite the presence of local treatment protocols in 65 % (119/183) of practitioners' institutions, 10 different strategies were commonly used when steroid premedication was taken incorrectly. The patients' questionnaire was completed by 72/87 (82.3 %) invitees. Respondents reported correctly taking their premedication 99 % (70/71) of the time. Patients felt steroids frequently caused side effects, the most common being sleep disturbance (35/72 = 49 %) and skin toxicity (16/72 = 22 %). CONCLUSION: Suboptimal adherence to steroid premedication prior to docetaxel administration is a common clinical challenge. There appears to be discordance between the practitioner and the patient experience. A single, universally accepted and used protocol for both pre- and post-medication and management when premedication is not taken as prescribed could improve adherence.",2015-11,26/11/2018 12:51,14/04/2020 08:34,,3269-3275,,11,23,,Support Care Cancer,,,,,,,,eng,,,,,,,PMID: 25933700,,,,Humans; Surveys and Questionnaires; Adult; Female; Male; Middle Aged; Medication Adherence/*statistics & numerical data; Drug Administration Schedule; Health Personnel; 00; Breast cancer; Breast Neoplasms/*drug therapy; Corticosteroid; Dexamethasone/administration & dosage/adverse effects/*therapeutic use; Docetaxel; Premedication; Premedication/*methods; Taxoids/*therapeutic use; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JPQ9W4G6,journalArticle,2015,"Kawonga, Mary; Blaauw, Duane; Fonn, Sharon",Exploring the use of social network analysis to measure communication between disease programme and district managers at sub-national level in South Africa.,Social science & medicine (1982),,1873-5347 0277-9536,10.1016/j.socscimed.2015.04.024,,"With increasing interest in maximising synergies between disease control programmes (DCP) and general health services (GHS), methods are needed to measure interactions between DCP and GHS actors. In South Africa, administrative integration reforms make GHS managers at decentralised level (district managers) responsible for the oversight of DCP operations within districts, with DCP managers (programme managers) providing specialist support. The reforms necessitate interdependence, but these actors work together ineffectively. Communication is crucial for joint working, but no research to assess communication between these actors has been done. This study explores the use of social network analysis (SNA) to measure the extent to which programme and district managers in South Africa communicate, using HIV monitoring and evaluation (M&E) as an exemplar. Data were collected from fifty one managers in two provinces during 2010-2011, to measure: a) one-on-one task-related communication - talking about the collation (verification, reporting) and use of HIV data for monitoring HIV interventions; and b) group communication through co-participating in management committees where HIV data are used for monitoring HIV interventions in districts. SNA measures were computed to describe actor centrality, network density (cohesion), and communication within and between respective manager groups. Block modelling was applied to identify management committees that connect respective manager groups. Results show HIV programme managers located at higher level communicated largely amongst themselves as a group (homophily), seldom talked to the district managers to whom they are supposed to provide specialist HIV M&E support, and rarely participated with them in management committees. This research demonstrates the utility of SNA as a tool for measuring the extent of communication between DCP and GHS actors at sub-national level. Actions are needed to bridge observed communication gaps in order to promote collaborative monitoring of HIV programme interventions within districts.",2015-06,26/11/2018 12:51,14/04/2020 08:34,,Jan-14,,,135,,Soc Sci Med,,,,,,,,eng,Copyright (c) 2015 Elsevier Ltd. All rights reserved.,,,,,,PMID: 25931377,,,,District; Health system; Delivery of Health Care/*organization & administration; Humans; Female; Male; Middle Aged; *Social Networking; *Communication; Social network analysis; 00; Administrative integration; Administrative Personnel/*organization & administration; Decentralisation; Disease control programme; HIV Infections/therapy; Monitoring and evaluation; South Africa; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 79K3LABV,journalArticle,2015,"Burn, Edward; Marshall, Alison L.; Miller, Yvette D.; Barnett, Adrian G.; Fjeldsoe, Brianna S.; Graves, Nicholas",The cost-effectiveness of the MobileMums intervention to increase physical activity among mothers with young children: a Markov model informed by a randomised controlled trial.,BMJ open,,2044-6055 2044-6055,10.1136/bmjopen-2014-007226,,"OBJECTIVES: To determine the cost-effectiveness of the MobileMums intervention. MobileMums is a 12-week programme which assists mothers with young children to be more physically active, primarily through the use of personalised SMS text-messages. DESIGN: A cost-effectiveness analysis using a Markov model to estimate and compare the costs and consequences of MobileMums and usual care. SETTING: This study considers the cost-effectiveness of MobileMums in Queensland, Australia. PARTICIPANTS: A hypothetical cohort of over 36 000 women with a child under 1 year old is considered. These women are expected to be eligible and willing to participate in the intervention in Queensland, Australia. DATA SOURCES: The model was informed by the effectiveness results from a 9-month two-arm community-based randomised controlled trial undertaken in 2011 and registered retrospectively with the Australian Clinical Trials Registry (ACTRN12611000481976). Baseline characteristics for the model cohort, treatment effects and resource utilisation were all informed by this trial. MAIN OUTCOME MEASURES: The incremental cost per quality-adjusted life year (QALY) of MobileMums compared with usual care. RESULTS: The intervention is estimated to lead to an increase of 131 QALYs for an additional cost to the health system of 1.1 million Australian dollars (AUD). The expected incremental cost-effectiveness ratio for MobileMums is 8608 AUD per QALY gained. MobileMums has a 98% probability of being cost-effective at a cost-effectiveness threshold of 64 000 AUD. Varying modelling assumptions has little effect on this result. CONCLUSIONS: At a cost-effectiveness threshold of 64 000 AUD, MobileMums would likely be a cost-effective use of healthcare resources in Queensland, Australia. TRIAL REGISTRATION NUMBER: Australian Clinical Trials Registry; ACTRN12611000481976.",29/04/2015,26/11/2018 12:51,14/04/2020 08:34,,e007226,,4,5,,BMJ Open,,,,,,,,eng,Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.,,,,,,PMID: 25926145 PMCID: PMC4420940,,,,"Humans; Program Evaluation; Surveys and Questionnaires; Cost-Benefit Analysis; Adult; Female; Markov Chains; Quality of Life; Text Messaging; Exercise; Risk Reduction Behavior; *Social Support; Health Knowledge, Attitudes, Practice; *Cell Phone; *Exercise/psychology; *Health Promotion; *Sedentary Lifestyle; Australia/epidemiology; behaviour change; Cost effectiveness; Economic evaluation; mHealth; Mothers/*psychology/statistics & numerical data; Queensland/epidemiology; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4T9CDRXS,journalArticle,2015,"Blanchet, Karl","Thinking shift on health systems: from blueprint health programmes towards resilience of health systems Comment on ""Constraints to applying systems thinking concepts in health systems: A regional perspective from surveying stakeholders in Eastern Mediterranean countries"".",International journal of health policy and management,,2322-5939 2322-5939,10.15171/ijhpm.2015.49,,"International health is still highly dominated by equilibrium approaches. The emergence of systems thinking in international health provides a great avenue to develop innovative health interventions adapted to changing contexts. The public health community, nevertheless, has the responsibility to translate concepts related to systems thinking and complexity into concrete research methods and interventions. One possibility is to consider the properties of systems such as resilience and adaptability as entry points to better understand how health systems react to shocks.",03/03/2015,26/11/2018 12:51,14/04/2020 08:34,,307-309,,5,4,,Int J Health Policy Manag,,,,,,,,eng,(c) 2015 by Kerman University of Medical Sciences.,,,,,,PMID: 25905481 PMCID: PMC4417634,,,,Humans; *Public Health; Practice Guidelines as Topic; *Global Health; Systems Analysis; *Delivery of Health Care; Health Planning; Complexity; Thinking; 00; Adaptability; Equilibrium; Resilience; Systems Thinking; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, R3TE6FM4,journalArticle,2015,"Son, Youn-Jung; Jeong, Senator; Kang, Byeong-Gwon; Kim, Sun-Hyung; Lee, Soo-Kyoung",Visualization of e-Health Research Topics and Current Trends Using Social Network Analysis.,Telemedicine journal and e-health : the official journal of the American Telemedicine Association,,1556-3669 1530-5627,10.1089/tmj.2014.0172,,"BACKGROUND: E-health has been grown rapidly with significant impact on quality and safety of healthcare. However, there is a large gap between the postulated and empirically demonstrated benefits of e-health technologies and a need for a clearer mapping of its conceptual domains. Therefore, this study aimed to critically review the main research topics and trends of international e-health through social network analysis. MATERIALS AND METHODS: Medical subject heading terms were used to retrieve 3,023 research articles published from 1979 through 2014 in the PubMed database. We extracted n-grams from the corpus using a text analysis program, generated co-occurrence networks, and then analyzed and visualized the networks using Pajek software. The hub and authority measures identified the most important research topics in e-health. Newly emerging topics by 4-year period units were identified as research trends. RESULTS: The most important research topics in e-health are personal health records (PHR), health information technology, primary care, mobile health, clinical decision support systems (CDSS), and so on. The eight groups obtained through ego network analysis can be divided into four semantically different areas, as follows: information technology, infrastructure, services, and subjects. Also, four historical trends in e-health research are identified: the first focusing on e-health and telemedicine; the second, PHR and monitoring; the third, CDSS and alert; and the fourth, mobile health and health literacy. CONCLUSIONS: This study promotes a systematic understanding of e-health by identifying topic networks, thereby contributing to the future direction of e-health research and education.",2015-05,26/11/2018 12:51,14/04/2020 08:35,,436-442,,5,21,,Telemed J E Health,,,,,,,,eng,,,,,,,PMID: 25885639,,,,"Humans; *Quality of Health Care; Forecasting; Research Design; *Social Networking; 00; Decision Support Systems, Clinical/*trends; *mobile health; *telehealth; *telemedicine; *e-health; *telenursing; Republic of Korea; Telemedicine/*trends; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Z69L3FBA,journalArticle,2015,"Silverman, Barry G.; Hanrahan, Nancy; Bharathy, Gnana; Gordon, Kim; Johnson, Dan","A systems approach to healthcare: agent-based modeling, community mental health, and population well-being.",Artificial intelligence in medicine,,1873-2860 0933-3657,10.1016/j.artmed.2014.08.006,,"PURPOSE: Explore whether agent-based modeling and simulation can help healthcare administrators discover interventions that increase population wellness and quality of care while, simultaneously, decreasing costs. Since important dynamics often lie in the social determinants outside the health facilities that provide services, this study thus models the problem at three levels (individuals, organizations, and society). METHODS: The study explores the utility of translating an existing (prize winning) software for modeling complex societal systems and agent's daily life activities (like a Sim City style of software), into a desired decision support system. A case study tests if the 3 levels of system modeling approach is feasible, valid, and useful. The case study involves an urban population with serious mental health and Philadelphia's Medicaid population (n=527,056), in particular. RESULTS: Section 3 explains the models using data from the case study and thereby establishes feasibility of the approach for modeling a real system. The models were trained and tuned using national epidemiologic datasets and various domain expert inputs. To avoid co-mingling of training and testing data, the simulations were then run and compared (Section 4.1) to an analysis of 250,000 Philadelphia patient hospital admissions for the year 2010 in terms of re-hospitalization rate, number of doctor visits, and days in hospital. Based on the Student t-test, deviations between simulated vs. real world outcomes are not statistically significant. Validity is thus established for the 2008-2010 timeframe. We computed models of various types of interventions that were ineffective as well as 4 categories of interventions (e.g., reduced per-nurse caseload, increased check-ins and stays, etc.) that result in improvement in well-being and cost. CONCLUSIONS: The 3 level approach appears to be useful to help health administrators sort through system complexities to find effective interventions at lower costs.",2015-02,26/11/2018 12:51,14/04/2020 08:35,,61-71,,2,63,,Artif Intell Med,,,,,,,,eng,Copyright (c) 2014 Elsevier B.V. All rights reserved.,,,,,,PMID: 25801593,,,,Humans; Health Promotion; United States; Cost-Benefit Analysis; *Systems Analysis; *Decision Support Techniques; Systems analysis; 1; *Mental Health; Hospitalization/economics; Philadelphia; Agent-based; Community healthcare; Community Mental Health Services/economics/*methods; Decision support; Medicaid; Mental health systems; Patient Readmission/economics; Readmission; ******To read; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, AZJWI4F7,journalArticle,2015,"Brydges, Ryan; Manzone, Julian; Shanks, David; Hatala, Rose; Hamstra, Stanley J.; Zendejas, Benjamin; Cook, David A.",Self-regulated learning in simulation-based training: a systematic review and meta-analysis.,Medical education,,1365-2923 0308-0110,10.1111/medu.12649,,"CONTEXT: Self-regulated learning (SRL) requires an active learner who has developed a set of processes for managing the achievement of learning goals. Simulation-based training is one context in which trainees can safely practise learning how to learn. OBJECTIVES: The purpose of the present study was to evaluate, in the simulation-based training context, the effectiveness of interventions designed to support trainees in SRL activities. We used the social-cognitive model of SRL to guide a systematic review and meta-analysis exploring the links between instructor supervision, supports or scaffolds for SRL, and educational outcomes. METHODS: We searched databases including MEDLINE and Scopus, and previous reviews, for material published until December 2011. Studies comparing simulation-based SRL interventions with another intervention for teaching health professionals were included. Reviewers worked independently and in duplicate to extract information on learners, study quality and educational outcomes. We used random-effects meta-analysis to compare the effects of supervision (instructor present or absent) and SRL educational supports (e.g. goal-setting study guides present or absent). RESULTS: From 11,064 articles, we included 32 studies enrolling 2482 trainees. Only eight of the 32 studies included educational supports for SRL. Compared with instructor-supervised interventions, unsupervised interventions were associated with poorer immediate post-test outcomes (pooled effect size: -0.34, p = 0.09; n = 19 studies) and negligible effects on delayed (i.e. > 1 week) retention tests (pooled effect size: 0.11, p = 0.63; n = 8 studies). Interventions including SRL supports were associated with small benefits compared with interventions without supports on both immediate post-tests (pooled effect size: 0.23, p = 0.22; n = 5 studies) and delayed retention tests (pooled effect size: 0.44, p = 0.067; n = 3 studies). CONCLUSIONS: Few studies in the simulation literature have designed SRL training to explicitly support trainees' capacity to self-regulate their learning. We recommend that educators and researchers shift from thinking about SRL as learning alone to thinking of SRL as comprising a shared responsibility between the trainee and the instructional designer (i.e. learning using designed supports that help prepare individuals for future learning).",2015-04,26/11/2018 12:51,14/04/2020 08:34,,368-378,,4,49,,Med Educ,,,,,,,,eng,(c) 2015 John Wiley & Sons Ltd.,,,,,,PMID: 25800297,,,,"Humans; *Computer Simulation; Models, Educational; Patient Simulation; *Learning; Educational Technology; 00; Education, Medical/*methods; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, I24FB898,journalArticle,2015,"Kharroubi, Samer A.; Edlin, Richard; Meads, David; Browne, Chantelle; Brown, Julia; McCabe, Christopher",Use of Bayesian Markov chain Monte Carlo methods to estimate EQ-5D utility scores from EORTC QLQ data in myeloma for use in cost-effectiveness analysis.,Medical decision making : an international journal of the Society for Medical Decision Making,,1552-681X 0272-989X,10.1177/0272989X15575285,,"BACKGROUND: Patient-reported outcome measures are an important component of the evidence for health technology appraisal. Their incorporation into cost-effectiveness analyses (CEAs) requires conversion of descriptive information into utilities. This can be done by using bespoke utility algorithms. Otherwise, investigators will often estimate indirect utility models for the patient-reported outcome measures using off-the-shelf utility data such as the",2015-04,26/11/2018 12:51,14/04/2020 08:34,,351-360,,3,35,,Med Decis Making,,,,,,,,eng,(c) The Author(s) 2015.,,,,,,PMID: 25784746,,,,Humans; Outcome Assessment (Health Care); Cost-Benefit Analysis; Quality-Adjusted Life Years; Female; Male; Middle Aged; Aged; *Markov Chains; *Quality of Life; *quality of life; *Bayes Theorem; *Bayesian methods; *cost-utility analysis; *EQ-5D; *mapping; *Monte Carlo Method; *multiple myeloma; *regression modeling.; Multiple Myeloma/*economics/*psychology/therapy; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, T6ZXA55K,journalArticle,2015,"Roberts, Mark S.",Dynamic simulation in health care comes of age.,Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research,,1524-4733 1098-3015,10.1016/j.jval.2015.02.006,,"For over half a century, the management science and industrial engineering community has applied simulation methods to problems in the delivery of health care services. Research in the 1970s used discrete event simulation (DES) to improve patient flows in emergency rooms and doctor’s offices [1], to optimize the geographic location of ambulance stations to minimize response time, and to plan for staffing needs in various hospital departments. In 1976, the growth in these efforts prompted the devotion of an entire issue of Operations Research to the application of these methods in health care, and there were predictions that simulation would revolutionize health care delivery in ways similar to the tremendous improvements that had been seen through its application in manufacturing and network control",2015-03,26/11/2018 12:51,14/04/2020 08:35,,143-144,,2,18,,Value Health,,,,,,,,eng,,,,,,,PMID: 25773548,,,,"Humans; *Models, Theoretical; Health Services Research/*methods; 1; Delivery of Health Care/*methods; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JBG7T8BP,journalArticle,2015,"Minion, Lindsey E.; Bai, Jiaru; Monk, Bradley J.; Robin Keller, L.; Ramez, Eskander N.; Forde, Gareth K.; Chan, John K.; Tewari, Krishnansu S.",A Markov model to evaluate cost-effectiveness of antiangiogenesis therapy using bevacizumab in advanced cervical cancer.,Gynecologic oncology,,1095-6859 0090-8258,10.1016/j.ygyno.2015.02.027,,"OBJECTIVE: To evaluate the cost-effectiveness of bevacizumab in recurrent/persistent and metastatic cervical cancer using recently reported updated survival and toxicology data. METHODS: A Markov decision tree based on the Gynecologic Oncology Group 240 randomized trial was created. The 2013 MediCare Services Drug Payment Table and Physician Fee Schedule provided costs. In the 5-year model subjects transitioned through the following states: response, progression, minor complications, severe complications, and death. Patients experiencing a health utility per month according to treatment effectiveness were calculated. Because cervical cancer survival is measured in months rather than years, results were reported in both quality adjusted cervical cancer life months and years (QALmonth, QALY), adjusted from a baseline of having advanced cervical cancer during a month. RESULTS: The estimated total cost of therapy with bevacizumab is approximately 13.2 times that for chemotherapy alone, adding $73,791 per 3.5months (0.29year) of life gained, resulting in an incremental cost-effectiveness ratio (ICER) of $21.083 per month of added life. The ICER increased to $5775 per month of added life and $24,597/QALmonth ($295,164/QALY) due to the smaller difference in QALmonths. With 75% bevacizumab cost reduction, the ICER is $6737/QALmonth ($80,844/QALY), which translates to $23,580 for the 3.5month (0.29year) gain in OS. CONCLUSIONS: Increased costs are primarily related to the cost of drug and not the management of bevacizumab-induced complications. Cost reductions in bevacizumab result in dramatic declines in the ICER, suggesting that cost reconciliation in advanced cervical cancer may be possible through the availability of biosimilars, and/or less expensive, equally efficacious anti-angiogenesis agents.",2015-06,26/11/2018 12:51,14/04/2020 08:34,,490-496,,3,137,,Gynecol Oncol,,,,,,,,eng,Copyright (c) 2015 Elsevier Inc. All rights reserved.,,,,,,PMID: 25766118,,,,"Humans; Cost-Benefit Analysis; Randomized Controlled Trials as Topic; Female; *Models, Economic; Markov Chains; Drug Costs; Decision Trees; Cost-effectiveness; Markov model; Angiogenesis Inhibitors/adverse effects/*economics/therapeutic use; Antiangiogenesis therapy; Antibodies, Monoclonal, Humanized/adverse effects/*economics/therapeutic use; Antineoplastic Combined Chemotherapy Protocols/*economics/therapeutic use; Bevacizumab; Biosimilar Pharmaceuticals/adverse effects/*economics/therapeutic use; Cervical cancer; Neoplasm Staging; Uterine Cervical Neoplasms/drug therapy/*economics/mortality/pathology; 00; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, S853KPIJ,journalArticle,2015,"Distelhorst, Sandra R.; Cleary, James F.; Ganz, Patricia A.; Bese, Nuran; Camacho-Rodriguez, Rolando; Cardoso, Fatima; Ddungu, Henry; Gralow, Julie R.; Yip, Cheng-Har; Anderson, Benjamin O.","Optimisation of the continuum of supportive and palliative care for patients with breast cancer in low-income and middle-income countries: executive summary of the Breast Health Global Initiative, 2014.",The Lancet. Oncology,,1474-5488 1470-2045,10.1016/S1470-2045(14)70457-7,,"Supportive care and palliative care are now recognised as critical components of global cancer control programmes. Many aspects of supportive and palliative care services are already available in some low-income and middle-income countries. Full integration of supportive and palliative care into breast cancer programmes requires a systematic, resource-stratified approach. The Breast Health Global Initiative convened three expert panels to develop resource allocation recommendations for supportive and palliative care programmes in low-income and middle-income countries. Each panel focused on a specific phase of breast cancer care: during treatment, after treatment with curative intent (survivorship), and after diagnosis with metastatic disease. The panel consensus statements were published in October, 2013. This Executive Summary combines the three panels' recommendations into a single comprehensive document covering breast cancer care from diagnosis through curative treatment into survivorship, and metastatic disease and end-of-life care. The recommendations cover physical symptom management, pain management, monitoring and documentation, psychosocial and spiritual aspects of care, health professional education, and patient, family, and caregiver education.",2015-03,26/11/2018 12:51,14/04/2020 08:34,,e137-147,,3,16,,Lancet Oncol,,,,,,,,eng,Copyright (c) 2015 Elsevier Ltd. All rights reserved.,,,,,,PMID: 25752564,,,,"Humans; Female; 00; *Income; Breast Neoplasms/diagnosis/economics/psychology/*therapy; Consensus; Delivery of Health Care, Integrated/economics/*standards; Developing Countries/*economics; Health Services Accessibility/economics/*standards; Palliative Care/economics/*standards; Patient Care Team/economics/standards; Poverty/*economics; Quality of Health Care/economics/*standards; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NCZVUTTM,journalArticle,2015,"Vuk, Jasna; Anders, Michael E.; Mercado, Cynthia C.; Kennedy, Robert L.; Casella, Jessie; Steelman, Susan C.",Impact of simulation training on self-efficacy of outpatient health care providers to use electronic health records.,International journal of medical informatics,,1872-8243 1386-5056,10.1016/j.ijmedinf.2015.02.003,,"OBJECTIVES: To examine whether simulation training enhanced self-efficacy of physicians and nurses who work in the outpatient setting to use electronic medical records, and whether the training changed their perceptions about the importance of electronic medical records (EMRs) in helping patients and improving patients' safety. METHODS: Two-hundred and ninety-three physicians and 94 nurses participated in the study. Participants first attended two computer classroom training sessions on how to use EMRs. Subsequently, the participants attended simulation training and practiced application of EMRs while encountering standardized patients. They answered questionnaires on a seven-point Likert-type scale prior to and immediately after simulation training. The questionnaires assessed their perceptions about the importance of EMRs in helping patients and improving patients' safety and their confidence and preparedness level to use EMRs. RESULTS: The overall self-efficacy of physicians and nurses to use EMRs increased after simulation training as compared to before simulation training. The physicians' and nurses' ratings about importance of EMRs to help patients' and improve patients' safety after simulation training were relatively unchanged compared to the ratings before simulation training. Additionally, participants described simulation training as exceptional, because it was an interactive learning opportunity to use EMRs within a simulated clinical setting with a simulated patient. CONCLUSIONS: Simulation training in the current study enhanced physicians' and nurses' level of self-confidence and preparedness to use EMRs. To train health care providers how to use EMRs, simulation training should be considered as an interactive and effective method of teaching prior to implementation of EMRs in medical institutions.",2015-06,26/11/2018 12:51,14/04/2020 08:35,,423-429,,6,84,,Int J Med Inform,,,,,,,,eng,Copyright (c) 2015 Elsevier Ireland Ltd. All rights reserved.,,,,,,PMID: 25746460,,,,"Humans; Surveys and Questionnaires; *Simulation Training; Female; Male; *Attitude of Health Personnel; Nurses; Hospitals, University; Patient Simulation; *Electronic Health Records; Physicians; 00; *Attitude to Computers; Self Efficacy; Simulation training; Arkansas; Electronic medical records; Outpatient Clinics, Hospital; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EGAZWWHZ,journalArticle,2015,"Schawo, Saskia; van der Kolk, Annemarie; Bouwmans, Clazien; Annemans, Lieven; Postma, Maarten; Buitelaar, Jan; van Agthoven, Michel; Hakkaart-van Roijen, Leona",Probabilistic Markov Model Estimating Cost Effectiveness of Methylphenidate Osmotic-Release Oral System Versus Immediate-Release Methylphenidate in Children and Adolescents: Which Information is Needed?,PharmacoEconomics,,1179-2027 1170-7690,10.1007/s40273-015-0259-x,,"BACKGROUND: Incidence of attention deficit hyperactivity disorder (ADHD) in children and adolescents has been increasing. The disorder results in high societal costs. Policymakers increasingly use health economic evaluations to inform decisions on competing treatments of ADHD. Yet, health economic evaluations of first-choice medication of ADHD in children and adolescents are scarce and generally do not include broader societal effects. OBJECTIVES: This study presents a probabilistic model and analysis of methylphenidate osmotic-release oral system (OROS) versus methylphenidate immediate-release (IR). We investigate and include relevant societal aspects in the analysis so as to provide cost-effectiveness estimates based on a broad societal perspective. METHODS: We enhanced an existing Markov model and determined the cost effectiveness of OROS versus IR for children and adolescents responding suboptimally to treatment with IR. Enhancements included screening of a broad literature base, updated utility values, inclusion of costs and effects on caregivers and a change of the model type from deterministic to probabilistic. RESULTS: The base case scenario resulted in lower incremental costs (euro-5815) of OROS compared with IR and higher incremental quality-adjusted life-year (QALY) gains (0.22). Scenario analyses were performed to determine sensitivity to changes in transition rates, utility of caregivers, medical costs of caregivers and daily medication dose. CONCLUSIONS: The results indicate that, for children responding suboptimally to treatment with IR, the beneficial effect of OROS on compliance may be worth the additional costs of medication. The presented model adds to the health economic information available for policymakers and to considerations on a broader perspective in cost-effectiveness analyses.",2015-05,26/11/2018 12:51,14/04/2020 08:35,,489-509,,5,33,,Pharmacoeconomics,,,,,,,,eng,,,,,,,PMID: 25715975 PMCID: PMC4544537,,,,"Humans; Quality-Adjusted Life Years; Treatment Outcome; *Cost-Benefit Analysis; Markov Chains; Child; Adolescent; Models, Economic; Patient Compliance; Administration, Oral; Attention Deficit Disorder with Hyperactivity/*drug therapy/economics; Central Nervous System Stimulants/*administration & dosage/*economics/pharmacokinetics/therapeutic use; Delayed-Action Preparations/economics; Methylphenidate/*administration & dosage/*economics/pharmacokinetics/therapeutic use; Osmosis; 00; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, N2VDX9Q3,journalArticle,2015,"Eppich, Walter; Cheng, Adam",Promoting Excellence and Reflective Learning in Simulation (PEARLS): development and rationale for a blended approach to health care simulation debriefing.,Simulation in healthcare : journal of the Society for Simulation in Healthcare,,1559-713X 1559-2332,10.1097/SIH.0000000000000072,,"STATEMENT: We describe an integrated conceptual framework for a blended approach to debriefing called PEARLS [Promoting Excellence And Reflective Learning in Simulation]. We provide a rationale for scripted debriefing and introduce a PEARLS debriefing tool designed to facilitate implementation of the new framework. The PEARLS framework integrates 3 common educational strategies used during debriefing, namely, (1) learner self-assessment, (2) facilitating focused discussion, and (3) providing information in the form of directive feedback and/or teaching. The PEARLS debriefing tool incorporates scripted language to guide the debriefing, depending on the strategy chosen. The PEARLS framework and debriefing script fill a need for many health care educators learning to facilitate debriefings in simulation-based education. The PEARLS offers a structured framework adaptable for debriefing simulations with a variety in goals, including clinical decision making, improving technical skills, teamwork training, and interprofessional collaboration.",2015-04,26/11/2018 12:51,14/04/2020 08:34,,106-115,,2,10,,Simul Healthc,,,,,,,,eng,,,,,,,PMID: 25710312,,,,"Humans; Clinical Competence; Learning; Simulation Training/*methods; *Formative Feedback; Patient Simulation; 00; Educational Measurement/*methods; Education, Medical/*methods; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, G59LR7KQ,journalArticle,2015,"Jensen, Sanne; Kushniruk, Andre W.; Nohr, Christian",Clinical simulation: A method for development and evaluation of clinical information systems.,Journal of biomedical informatics,,1532-0480 1532-0464,10.1016/j.jbi.2015.02.002,,"Use of clinical simulation in the design and evaluation of eHealth systems and applications has increased during the last decade. This paper describes a methodological approach for using clinical simulations in the design and evaluation of clinical information systems. The method is based on experiences from more than 20 clinical simulation studies conducted at the ITX-lab in the Capital Region of Denmark during the last 5 years. A ten-step approach to conducting simulations is presented in this paper. To illustrate the approach, a clinical simulation study concerning implementation of Digital Clinical Practice Guidelines in a prototype planning and coordination module is presented. In the case study potential benefits were assessed in a full-scale simulation test including 18 health care professionals. The results showed that health care professionals can benefit from such a module. Unintended consequences concerning terminology and changes in the division of responsibility amongst healthcare professionals were also identified, and questions were raised concerning future workflow across sector borders. Furthermore unexpected new possible benefits concerning improved communication, content of information in discharge letters and quality management emerged during the testing. In addition new potential groups of users were identified. The case study is used to demonstrate the potential of using the clinical simulation approach described in the paper.",2015-04,26/11/2018 12:51,14/04/2020 08:34,,65-76,,,54,,J Biomed Inform,,,,,,,,eng,Copyright (c) 2015 Elsevier Inc. All rights reserved.,,,,,,PMID: 25684129,,,,"Humans; Evaluation; Electronic Health Records; *Models, Theoretical; Health Personnel; Denmark; *Telemedicine; *Health Services Research; User-Computer Interface; 00; *Health Information Systems; Clinical simulation; Clinical information systems; Clinical practice guidelines; eHealth; Human factors; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GPMWJ2ZN,journalArticle,2015,"Stuckler, David; Reeves, Aaron; Karanikolos, Marina; McKee, Martin",The health effects of the global financial crisis: can we reconcile the differing views? A network analysis of literature across disciplines.,"Health economics, policy, and law",,1744-134X 1744-1331,10.1017/S1744133114000255,,"Why are researchers studying the health effects of economic change reaching markedly varying conclusions? To understand these differences, we first systematically searched Web of Science for the literature on recessions and health yielding 461 articles and 14,401 cited documents. We then undertook a network analysis of co-citation pattern by disciplines, journals and backgrounds of the authors, followed by a chronological review of the literature, to trace the evolution of ideas. We then examined the extent to which earlier literature predicted what has happened in the 2007-2012 crisis. Our analysis finds the literature is dominated by disciplinary silos, with economics studies predominantly citing each other and relative isolation of psychiatry and substance abuse journals. Different philosophical approaches to assessing causality appear to contribute to varying interpretations, a tendency that is unlikely to be resolved without a shift in research norms. We conclude by calling for more inter-disciplinary research that combines empirical findings with a search for plausible mechanisms. This approach would evaluate not only the effects of economic shocks but also the mechanisms that offer protection against them.",2015-01,26/11/2018 12:51,14/04/2020 08:35,,83-99,,1,10,,Health Econ Policy Law,,,,,,,,eng,,,,,,,PMID: 25662198,,,,Humans; *Health Status; *Global Health; Bibliometrics; 00; *Economic Recession; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, L39K5L2L,journalArticle,2015,"Zachariah, Justin P.; Samnaliev, Mihail",Echo-based screening of rheumatic heart disease in children: a cost-effectiveness Markov model.,Journal of medical economics,,1941-837X 1369-6998,10.3111/13696998.2015.1006366,,"OBJECTIVES: To project the cost-effectiveness of population-based echo screening to prevent rheumatic heart disease (RHD) consequences. BACKGROUND: RHD is a leading cause of cardiovascular mortality and morbidity during adolescence and young adulthood in low- and middle-per capita income settings. Echocardiography-based screening approaches can dramatically expand the number of children identified at risk of progressive RHD. Cost-effectiveness analysis can inform public health agencies and payers about the net economic benefit of such large-scale population-based screening. METHODS: A Markov model was constructed comparing a no-screen to echo screen approach. The echo screen program was modeled as a 2-staged screen of a cohort of 11-year-old children with initial short screening performed by dedicated technicians and follow-up complete echo by cardiologists. Penicillin RHD prophylaxis was modeled to only reduce rheumatic fever recurrence-related exacerbation. Quality-adjusted life years (QALYs) and societal costs (in 2010 Australian dollars) associated with each approach were estimated. One-way, two-way and probabilistic sensitivity analyses were performed on RHD prevalence and transition probabilities; echocardiography test characteristics; and societal level costs including supplies, transportation, and labor. RESULTS: The incremental costs and QALYs of the screen compared to no screen strategy were -$432 (95% CI = -$1357 to $575) and 0.007 (95% CI = -0.0101 to 0.0237), respectively. The joint probability that the screen was both less costly and more effective exceeded 80%. Sensitivity analyses suggested screen strategy dominance depends mostly on the probability of transitioning out of sub-clinical RHD. CONCLUSION: Two-stage echo RHD screening and secondary prophylaxis may achieve modestly improved outcomes at lower cost compared to clinical detection and deserves closer attention from health policy stakeholders.",2015-06,26/11/2018 12:51,14/04/2020 08:35,,410-419,,6,18,,J Med Econ,,,,,,,,eng,,,,,,,PMID: 25629653 PMCID: PMC4497526,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Child; Pediatrics; *Markov Chains; Prevalence; Mass Screening/*economics; *Models, Econometric; Anti-Bacterial Agents/economics/therapeutic use; Antibiotic Prophylaxis/methods; Cost-benefit analysis; Echocardiography; Echocardiography/*economics; Heart Valve Prosthesis/economics; Northern Territory/epidemiology; Penicillin G Benzathine/economics/therapeutic use; Recurrence; Rheumatic Fever/prevention & control; Rheumatic heart disease; Rheumatic Heart Disease/*diagnosis/economics; Valves; 00; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, T94Z9JB9,journalArticle,2015,"Barnett, Tony; Hoang, Ha; Cross, Merylin; Bridgman, Heather",Interprofessional practice and learning in a youth mental health service: A case study using network analysis.,Journal of interprofessional care,,1469-9567 1356-1820,10.3109/13561820.2015.1004042,,"Few studies have examined interprofessional practice (IPP) from a mental health service perspective. This study applied a mixed-method approach to examine the IPP and learning occurring in a youth mental health service in Tasmania, Australia. The aims of the study were to investigate the extent to which staff were networked, how collaboratively they practiced and supported student learning, and to elicit the organisation's strengths and opportunities regarding IPP and learning. Six data sets were collected: pre- and post-test readiness for interprofessional learning surveys, Social Network survey, organisational readiness for IPP and learning checklist, ""talking wall"" role clarification activity, and observations of participants working through a clinical case study. Participants (n = 19) were well-networked and demonstrated a patient-centred approach. Results confirmed participants' positive attitudes to IPP and learning and identified ways to strengthen the organisation's interprofessional capability. This mixed-method approach could assist others to investigate IPP and learning.",2015,26/11/2018 12:51,14/04/2020 08:34,,512-514,,5,29,,J Interprof Care,,,,,,,,eng,,,,,,,PMID: 25625892,,,,Humans; Adult; Learning; Young Adult; Child; Adolescent; *Interprofessional Relations; Health Personnel/*education; Patient Care Team/*organization & administration; Cooperative Behavior; *Community Networks; 00; Mental Health Services/*organization & administration; Case study; collaborative care; interprofessional education; interprofessional learning; interprofessional practice; multidisciplinary; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, AB78MYPK,journalArticle,2015,"Lay-Yee, Roy; Milne, Barry; Davis, Peter; Pearson, Janet; McLay, Jessica",Determinants and disparities: a simulation approach to the case of child health care.,Social science & medicine (1982),,1873-5347 0277-9536,10.1016/j.socscimed.2015.01.025,,"Though there is much agreement on the importance of the social determinants of health, debate continues on suitable empirically-based models to underpin efforts to tackle health and health care disparities. We demonstrate an approach that uses a dynamic micro-simulation model of the early life course, based on longitudinal data from a New Zealand cohort of children born in 1977, and counterfactual reasoning applied to a range of outcomes. The focus is on health service use with a comparison to outcomes in non-health domains, namely educational attainment and antisocial behaviour. We show an application of the model to test scenarios based on modifying key determinants and assessing the impact on putative outcomes. We found that appreciable improvement was only effected by modifying multiple determinants; structural determinants were relatively more important than intermediary ones as potential policy levers; there was a social gradient of effect; and interventions bestowed the greatest benefit to the most disadvantaged groups with a corresponding reduction in disparities between the worst-off and the best-off. Our findings provide evidence on how public policy initiatives might be more effective acting broadly across sectors and across social groups, and thus make a real difference to the most disadvantaged.",2015-03,26/11/2018 12:51,14/04/2020 08:34,,202-211,,,128,,Soc Sci Med,,,,,,,,eng,Copyright (c) 2015 Elsevier Ltd. All rights reserved.,,,,,,PMID: 25618608,,,,"Humans; New Zealand; Child; Adolescent; Computer Simulation; Child, Preschool; Infant; *Child Health; Infant, Newborn; *Health Status Disparities; Public Policy; *Social Determinants of Health; 1; Health care; Children; Disparities; Micro-simulation; Social determinants; Microsimulation; 210",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PKLHSWPH,journalArticle,2015,"Sonntag, D.; Ali, S.; Lehnert, T.; Konnopka, A.; Riedel-Heller, S.; Konig, H.-H.",Estimating the lifetime cost of childhood obesity in Germany: Results of a Markov Model.,Pediatric obesity,,2047-6310 2047-6302,10.1111/ijpo.278,,"BACKGROUND: Child obesity is a growing public health concern. Excess weight in childhood is known to be associated with a high risk of obesity and obesity-related comorbidities in adulthood. OBJECTIVES: This study quantifies lifetime excess costs of overweight and obese adults in Germany taking the history of obesity in childhood into account. METHODS: A two-stage Markov cohort state transition model was developed. At stage 1, the distribution of body mass index (BMI) categories was tracked from childhood (ages 3-17) to adulthood (age 17 and up). Based on these results, it was distinguished whether adults had been normal in weight or overweight/obese as child. At stage 2, age-specific and lifetime costs from age 18 onwards were simulated in two further Markov cohort models, one for each of the two BMI groups. Model parameter values were obtained from the German Interview and Examination Survey for Children and Adolescents (KiGGS), the German Microcensus 2009 and published literature. RESULTS: When compared with normal weight adults, lifetime excess costs are higher among adults who had been overweight or obese at any point during childhood. For 18-year-old women (men), who have been overweight/obese during their childhood (ages 3-17), undiscounted lifetime excess costs are estimated at euro19,479 (euro14,524), with 60% (67%) occurring beyond age 60. Discounted (3%) lifetime excess costs are considerably lower, amounting to euro4262 for men and euro7028 for women. CONCLUSIONS: Because childhood obesity determines healthcare costs occurring in adulthood, interventions preventing the persistence of child obesity and obesity-related comorbidities during adulthood could have a substantial impact on reducing the burden of the obesity epidemic.",2015-12,26/11/2018 12:51,14/04/2020 08:34,,416-422,,6,10,,Pediatr Obes,,,,,,,,eng,(c) 2015 World Obesity.,,,,,,PMID: 25612250,,,,"Humans; Health Care Costs; Adult; Female; Male; Middle Aged; Risk Factors; Markov Chains; Child; Adolescent; Comorbidity; Child, Preschool; Markov model; *Body Mass Index; obesity; Health Surveys; 1; Reference Values; Costs; Germany/epidemiology; lifetime; Pediatric Obesity/*complications/*economics/epidemiology/prevention & control; Weight Gain; 310",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JKEV3A9S,journalArticle,2015,"Watters, Colm; Reedy, Gabriel; Ross, Alastair; Morgan, Nicola J.; Handslip, Rhodri; Jaye, Peter",Does interprofessional simulation increase self-efficacy: a comparative study.,BMJ open,,2044-6055 2044-6055,10.1136/bmjopen-2014-005472,,"OBJECTIVES: In this work, we have compared uniprofessional and interprofessional versions of a simulation education intervention, in an attempt to understand more about whether it improves trainees' self-efficacy. BACKGROUND: Interprofessionalism has been climbing the healthcare agenda for over 50 years. Simulation education attempts to create an environment for healthcare professionals to learn, without potential safety risks for patients. Integrating simulation and interprofessional education can provide benefits to individual learners. SETTING: The intervention took place in a high-fidelity simulation facility located on the campus of a large urban hospital. The centre provides educational activities for an Academic Health Sciences Centre. Approximately 2500 staff are trained at the centre each year. PARTICIPANTS: One hundred and fifteen nurses and midwives along with 156 doctors, all within the early years of their postgraduate experience participated. All were included on the basis of their ongoing postgraduate education. METHODS: Each course was a one-day simulation course incorporating five clinical and one communication scenarios. After each a facilitated debriefing took place. A mixed methods approach utilised precourse and postcourse questionnaires measuring self-efficacy in managing emergency situations, communication, teamwork and leadership. RESULTS: Thematic analysis of qualitative data showed improvements in communication/teamwork and leadership, for doctors and nurses undergoing simulation training. These findings were confirmed by statistical analysis showing that confidence ratings improved in nurses and doctors overall (p<0.001). Improved outcomes from baseline were observed for interprofessional versus uniprofessional trained nurses (n=115; p<0.001). Postcourse ratings for doctors showed that interprofessional training was significantly associated with better final outcomes for a communication/teamwork dimension (n=156; p<0.05). CONCLUSIONS: This study provides evidence that simulation training enhances participants' self-efficacy in clinical situations. It also leads to increases in their perceived abilities relating to communication/teamwork and leadership/management of clinical scenarios. Interprofessional training showed increased positive effects on self-efficacy for nurses and doctors.",13/01/2015,26/11/2018 12:51,14/04/2020 08:35,,e005472,,1,5,,BMJ Open,,,,,,,,eng,Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.,,,,,,PMID: 25586366 PMCID: PMC4298099,,,,"Humans; Surveys and Questionnaires; Female; Male; Patient Care Team; *Clinical Competence; *Self Efficacy; *Attitude of Health Personnel; *Interprofessional Relations; Health Personnel/*education; Nurses; MEDICAL EDUCATION & TRAINING; Midwifery; Physicians; 00; Education, Graduate/*methods; EDUCATION & TRAINING (see Medical Education & Training); QUALITATIVE RESEARCH; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, AAXIZ53U,journalArticle,2015,"Kvamme, Maria K.; Lie, Elisabeth; Uhlig, Till; Moger, Tron A.; Kvien, Tore K.; Kristiansen, Ivar S.",Cost-effectiveness of TNF inhibitors vs synthetic disease-modifying antirheumatic drugs in patients with rheumatoid arthritis: a Markov model study based on two longitudinal observational studies.,"Rheumatology (Oxford, England)",,1462-0332 1462-0324,10.1093/rheumatology/keu460,,"OBJECTIVE: The objective of this study was to estimate the additional costs and health benefits of adding a TNF inhibitor (TNFi) (adalimumab, certolizumab, etanercept, golimumab, infliximab) to a synthetic DMARD (sDMARD), e.g. MTX, in patients with RA. METHODS: We developed the Norwegian RA model as a Markov model simulating 10 years of treatment with either TNFi plus sDMARDs (TNFi strategy) or sDMARDs alone (synthetic strategy). Patients in both strategies started in one of seven health states, based on the Short Form-6 Dimensions (SF-6D). The patients could move to better or worse health states according to transition probabilities. In the TNFi strategy, patients could stay on TNFi (including switch of TNFi), or switch to non-TNFi-biologics (abatacept, rituximab, tocilizumab), sDMARDs or no DMARD. In the synthetic strategy, patients remained on sDMARDs. Data from two observational studies were used for the assessment of resource use and utilities in the health states. Health benefits were evaluated using the EuroQol-5 Dimensions (EQ-5D) and SF-6D. RESULTS: The Norwegian RA model predicted that 10-year discounted health care costs totalled euro124,942 (euro475,266 including production losses) for the TNFi strategy and euro65,584 (euro436,517) for the synthetic strategy. The cost per additionally gained quality-adjusted life-year of adding a TNFi was euro92,557 (euro60,227 including production losses) using SF-6D and euro61,285 (euro39,841) using EQ-5D. Including health care costs only, the probability that TNFi treatment was cost-effective was 90% when using EQ-5D, assuming a Norwegian willingness-to-pay level of euro67,300. CONCLUSION: TNFi treatment for RA is cost-effective when accounting for production losses. Excluding production losses, TNFi treatment is cost-effective using EQ-5D, but not SF-6D.",2015-07,26/11/2018 12:51,14/04/2020 08:34,,1226-1235,,7,54,,Rheumatology (Oxford),,,,,,,,eng,"(c) The Author 2015. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.",,,,,,PMID: 25573840,,,,"Humans; Quality-Adjusted Life Years; Treatment Outcome; Adult; Female; Male; Middle Aged; Young Adult; Aged; *Markov Chains; Adolescent; Aged, 80 and over; cost-effectiveness; Models, Statistical; Health Status; Markov chain; Longitudinal Studies; Adalimumab; Antibodies, Monoclonal, Humanized/economics/therapeutic use; Antibodies, Monoclonal/economics/therapeutic use; antirheumatic agent; Antirheumatic Agents/*economics/*therapeutic use; arthritis; Arthritis, Rheumatoid/*drug therapy; Biological Products/*economics/*therapeutic use; Cost-Benefit Analysis/*statistics & numerical data; Etanercept; Immunoglobulin G/economics/therapeutic use; Infliximab; Methotrexate/economics/therapeutic use; Norway; receptors; Receptors, Tumor Necrosis Factor/therapeutic use; rheumatoid; Tumor Necrosis Factor-alpha/*antagonists & inhibitors; tumour necrosis factor; type I; 00; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LTPNQZK5,journalArticle,2015,"Stollenwerk, B.; Bartmus, T.; Klug, F.; Stock, S.; Muller, D.",Cost-effectiveness of hip protector use on a geriatric ward in Germany: a Markov model.,Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA,,1433-2965 0937-941X,10.1007/s00198-014-3008-7,,"UNLABELLED: In this study, we determined the cost-effectiveness of hip protector use compared with no hip protector on a geriatric ward in Germany. From both the societal and the statutory health insurance (SHI) perspectives, the cost-effectiveness ratios for the provision of hip protectors were below 12,000/quality-adjusted life year (QALY) even if unrelated costs in added life years were included. INTRODUCTION: The aim of this study is to determine the cost-effectiveness of the provision of hip protectors compared with no hip protectors on a geriatric ward in Germany. METHODS: A lifetime decision-analytic Markov model was developed. Costs were measured from the societal and from the statutory health insurance (SHI) perspectives and comprised direct medical, non-medical and unrelated costs in additional life years gained. Health outcomes were measured in terms of quality-adjusted life years (QALYs). To reflect several levels of uncertainty, first- and second-order Monte Carlo simulation (MCS) approaches were applied. RESULTS: Hip protector use compared with no hip protector results in savings (costs, -5.1/QALYs, 0.003) for the societal perspective. For the SHI perspective, the incremental cost-effectiveness ratio was 4416 /QALY (costs, +13.4). If unrelated costs in life years gained were included, the cost-effectiveness ratio increases to 9794/QALY for the societal perspective and to 11,426/QALY for the SHI perspective. In the MCS, for the societal perspective without unrelated costs, 47 % of simulations indicated hip protectors to be cost saving (i.e. lower costs and higher effects). CONCLUSION: Although the gain in QALYs due to the provision of providing hip protectors to patients on geriatric wards is small, all scenarios showed acceptable cost-effectiveness ratios or even savings.",2015-04,26/11/2018 12:51,14/04/2020 08:35,,1367-1379,,4,26,,Osteoporos Int,,,,,,,,eng,,,,,,,PMID: 25572047,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Female; Male; Aged; Markov Chains; Decision Support Techniques; Aged, 80 and over; Health Care Costs/*statistics & numerical data; Sensitivity and Specificity; *Models, Econometric; Germany; Health Services Research/methods; Hip Fractures/*economics/*prevention & control; Patients' Rooms/*economics; Protective Devices/*economics; 1; Markov; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, C5GYH5GZ,journalArticle,2014,"Flood, Colleen; Gross, Aeyal",Litigating the right to health: what can we learn from a comparative law and health care systems approach.,Health and human rights,,2150-4113 1079-0969,,,"This article presents research demonstrating that the right to health plays different roles in different types of health systems. In high-income countries with tax-funded health systems, we usually encounter a lack of an enforceable right to heath. In contrast, rights play a more significant role in social health insurance/managed competition systems (which are present in a mixture of high-income and middle-income countries). There is concern, for example in Colombia, that a high volume of rights litigation can challenge the very sustainability of a public health care system and distort resources away from those most in need. Finally, in middle-income countries with big gaps between a poor public health system and a rich private one, we are more likely to find an express constitutional right to health care (or one is inferred from, for example, the right to life). In some of these countries, constitutional rights were included as part of the transition to democracy and an attempt to address huge inequities within society. Here the scale of health inequities suggests that courts need to be bolder in their interpretation of health care rights. We conclude that in adjudicating health rights, courts should scrutinize decision-making through the lens of health equity and equality to better achieve the inherent values of health human rights.",11/12/2014,26/11/2018 12:51,14/04/2020 08:34,,E62-72,,2,16,,Health Hum Rights,,,,,,,,eng,"Copyright (c) 2014 Gross and Flood. This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original author and source are credited.",,,,,,PMID: 25569725,,,,"Humans; 00; *Legislation as Topic; Delivery of Health Care/*legislation & jurisprudence; Financing, Government/legislation & jurisprudence; Judicial Role; Patient Rights/*legislation & jurisprudence; State Medicine/legislation & jurisprudence; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XQMPV644,journalArticle,2014,"Banerjee, Samprit; Cafri, Guy; Isaacs, Abby J.; Graves, Stephen; Paxton, Elizabeth; Marinac-Dabic, Danica; Sedrakyan, Art",A distributed health data network analysis of survival outcomes: the International Consortium of Orthopaedic Registries perspective.,The Journal of bone and joint surgery. American volume,,1535-1386 0021-9355,10.2106/JBJS.N.00642,,"The International Consortium for Orthopaedic Registries is a multinational initiative established by the United States Food and Drug Administration to develop a health data network aimed at providing a robust infrastructure to facilitate evidence-based decision-making on performance of medical devices. Through the International Consortium for Orthopaedic Registries, individual data holders have complete control of their data and can choose to participate in studies of their choice. In this article, we present an overview of the data extraction process and the analytic strategy employed to answer several device performance-related questions in total hip arthroplasty and total knee arthroplasty. In the process, we discuss some nuances pertinent to International Consortium for Orthopaedic Registries data that pose certain statistical challenges, and we briefly suggest strategies to be adopted to address them.",17/12/2014,26/11/2018 12:51,14/04/2020 08:34,,07-Nov,,,96 Suppl 1,,J Bone Joint Surg Am,,,,,,,,eng,"Copyright (c) 2014 by The Journal of Bone and Joint Surgery, Incorporated.",,,,,,PMID: 25520413 PMCID: PMC4271424,,,,"Humans; United States; Registries; 00; Orthopedics; *Arthroplasty, Replacement, Hip; *Data Mining; *Arthroplasty, Replacement, Knee; *Hip Prosthesis; *Knee Prosthesis; Prosthesis Design; United States Food and Drug Administration; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EHQ5XH2G,journalArticle,2015,"Cashin, Cheryl; Phuong, Nguyen Khanh; Shain, Ryan; Oanh, Tran Thi Mai; Thuy, Nguyen Thi",A simple simulation model as a tool to assess alternative health care provider payment reform options in Vietnam.,Global public health,,1744-1706 1744-1692,10.1080/17441692.2014.986156,,"Vietnam is currently considering a revision of its 2008 Health Insurance Law, including the regulation of provider payment methods. This study uses a simple spreadsheet-based, micro-simulation model to analyse the potential impacts of different provider payment reform scenarios on resource allocation across health care providers in three provinces in Vietnam, as well as on the total expenditure of the provincial branches of the public health insurance agency (Provincial Social Security [PSS]). The results show that currently more than 50% of PSS spending is concentrated at the provincial level with less than half at the district level. There is also a high degree of financial risk on district hospitals with the current fund-holding arrangement. Results of the simulation model show that several alternative scenarios for provider payment reform could improve the current payment system by reducing the high financial risk currently borne by district hospitals without dramatically shifting the current level and distribution of PSS expenditure. The results of the simulation analysis provided an empirical basis for health policy-makers in Vietnam to assess different provider payment reform options and make decisions about new models to support health system objectives.",2015,26/11/2018 12:51,14/04/2020 08:34,,S104-119,,,10 Supppl 1,,Glob Public Health,,,,,,,,eng,,,,,,,PMID: 25514050,,,,"*Health Policy; Humans; Health Services Research; Computer Simulation; Models, Econometric; 1; Health Care Reform/*economics; health financing; provider payment; Reimbursement Mechanisms/*economics; simulation analysis; universal coverage; Universal Coverage/*economics; Vietnam; 310",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, M9DYQZC4,journalArticle,2014,"Schwendicke, Falk; Paris, Sebastian; Stolpe, Michael",Cost-effectiveness of caries excavations in different risk groups - a micro-simulation study.,BMC oral health,,1472-6831 1472-6831,10.1186/1472-6831-14-153,,"BACKGROUND: Whilst being the most prevalent disease worldwide, dental caries is increasingly concentrated in high-risk populations. New caries treatments should therefore be evaluated not only in terms of their cost-effectiveness in individuals, but also their effects on the distribution of costs and benefits across different populations. To treat deep caries, there are currently three strategies: selective (one-step incomplete), stepwise (two-step incomplete) and complete excavation. Building on prior research that found selective excavation generally cost-effective, we compared the costs-effectiveness of different excavations in low- and high-risk patients, hypothesizing that selective excavation had greater cost-effectiveness-advantages in patients with high compared with low risk. METHODS: An average tooth-level Markov-model was constructed following the posterior teeth in an initially 18-year old male individual, either with low or high risk, over his lifetime. Risk was assumed to be predicted by several parameters (oral hygiene, social position, dental service utilization), with evidence-based transition probabilities or hazard functions being adjusted for different risk status where applicable. Total lifetime treatment costs were estimated for German healthcare, with both mixed public-private and only private out-of-pocket costs being calculated. For cost-effectiveness-analysis, micro-simulations were performed and joint parameter uncertainty introduced by random sampling of probabilities. Cohort analyses were used for assessing the underlying reasons for potential differences between strategies and populations. RESULTS: Selective excavation was more effective and less costly than both alternatives regardless of an individual's risk. All three strategies were less effective and more costly in patients with high compared with low risk, whilst the differences between risk groups were smallest for selective excavation. Thus, the cost-effectiveness-advantages of selective excavation were more pronounced in high-risk groups, who also benefitted the most from reduced private out-of-pocket treatment costs. CONCLUSIONS: Whilst caries excavation does not tackle the underlying sources for both the development of caries lesions and the potential differences of individuals' risk status, selective excavation seems most suitable to treat deep lesions, especially in patients with high risk, who over-proportionally benefit from the resulting health-gains and cost-savings.",15/12/2014,26/11/2018 12:51,14/04/2020 08:35,,153,,,14,,BMC Oral Health,,,,,,,,eng,,,,,,,PMID: 25511906 PMCID: PMC4279684,,,,"Humans; Cost-Benefit Analysis; Health Care Costs; Male; Cohort Studies; Markov Chains; Risk Assessment; Adolescent; Computer Simulation; Models, Theoretical; Uncertainty; Disease Progression; Social Class; Germany; *Dental Caries Susceptibility; Dental Care/utilization; Dental Caries/*economics/therapy; Dental Cavity Preparation/*economics; Dental Restoration, Permanent/economics; DMF Index; Financing, Organized; Oral Hygiene; Root Canal Therapy/economics; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4UTX6F4A,journalArticle,2014,"Tomblin Murphy, Gail; MacKenzie, Adrian; Guy-Walker, Joan; Walker, Claudette",Needs-based human resources for health planning in Jamaica: using simulation modelling to inform policy options for pharmacists in the public sector.,Human resources for health,,1478-4491 1478-4491,10.1186/1478-4491-12-67,,"BACKGROUND: Planning for human resources for health (HRH) is central to health systems strengthening around the world, including in the Caribbean and Jamaica. In an effort to align Jamaica's health workforce with the changing health needs of its people, a partnership was established between Jamaican and Canadian partners. The purpose of the work described in this paper is to describe the development and application of a needs-based HRH simulation model for pharmacists in Jamaica's largest health region. METHODS: Guided by a Steering Committee of Jamaican stakeholders, a simulation modelling approach originally developed in Canada was adapted for the Jamaican context. The purpose of this approach is to promote understanding of how various factors affect the supply of and/or requirements for HRH in different scenarios, and to identify policy levers for influencing each of these under different future scenarios. This is done by integrating knowledge of different components of the health care system into a single tool that shows how changes to different parameters affect HRH supply or requirements. Data to populate the model were obtained from multiple administrative databases and key informants. Findings were validated with the Steering Committee. RESULTS: The model estimated an initial shortage of 110 full-time equivalent (FTE) pharmacists in the South East Region that, without intervention, would increase to a shortage of about 150 FTEs over a 15-year period. In contrast to the relatively small impact of a large enrollment increase in Jamaica's pharmacy training programme, interventions to increase recruitment of pharmacists to the public sector, or improve productivity - through, for example, the use of support staff and/or new technologies - may have much greater impact on reducing this shortage. CONCLUSIONS: The model represents an improvement on the HRH planning tools previously used in Jamaica in that it supports the estimation of HRH requirements based directly on measures of population health need. Both the profession (pharmacists) and country (Jamaica) considered here are under-studied. Further investments by Jamaica's MoH in continuing to build capacity to use such models, in combination with their efforts to enhance health information systems, will support better informed HRH planning in Jamaica.",06/12/2014,26/11/2018 12:51,14/04/2020 08:34,,67,,,12,,Hum Resour Health,,,,,,,,eng,,,,,,,PMID: 25481658 PMCID: PMC4292822,,,,"Humans; Public Sector; Canada; Models, Theoretical; 1; *Health Services Needs and Demand; Health Planning/*methods; Jamaica; Personnel Staffing and Scheduling/*statistics & numerical data; Pharmacists/*statistics & numerical data; Discrete event; 310",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4L7CT5KS,journalArticle,2015,"Kontturi, Leena-Stiina; Collin, Estelle C.; Murtomaki, Lasse; Pandit, Abhay S.; Yliperttula, Marjo; Urtti, Arto",Encapsulated cells for long-term secretion of soluble VEGF receptor 1: Material optimization and simulation of ocular drug response.,European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V,,1873-3441 0939-6411,10.1016/j.ejpb.2014.10.005,,"Anti-angiogenic therapies with vascular endothelial growth factor (VEGF) inhibiting factors are effective treatment options for neovascular diseases of the retina, but these proteins can only be delivered as intravitreal (IVT) injections. To sustain a therapeutic drug level in the retina, VEGF inhibitors have to be delivered frequently, every 4-8weeks, causing inconvenience for the patients and expenses for the healthcare system. The aim of this study was to investigate cell encapsulation as a delivery system for prolonged anti-angiogenic treatment of retinal neovascularization. Genetically engineered ARPE-19 cells secreting soluble vascular endothelial growth factor receptor 1 (sVEGFR1) were encapsulated in a hydrogel of cross-linked collagen and interpenetrating hyaluronic acid (HA). The system was optimized in terms of matrix composition and cell density, and long-term cell viability and protein secretion measurements were performed. sVEGFR1 ARPE-19 cells in the optimized hydrogel remained viable and secreted sVEGFR1 at a constant rate for at least 50days. Based on pharmacokinetic/pharmacodynamic (PK/PD) modeling, delivery of sVEGFR1 from this cell encapsulation system is expected to lead only to modest VEGF inhibition, but improvements of the protein structure and/or secretion rate should result in strong and prolonged therapeutic effect. In conclusion, the hydrogel matrix herein supported the survival and protein secretion from the encapsulated cells. The PK/PD simulation is a convenient approach to predict the efficiency of the cell encapsulation system before in vivo experiments.",2015-09,26/11/2018 12:51,14/04/2020 08:34,,387-397,,Pt B,95,,Eur J Pharm Biopharm,,,,,,,,eng,Copyright (c) 2014 Elsevier B.V. All rights reserved.,,,,,,PMID: 25460143,,,,"Humans; *Models, Biological; Time Factors; Drug Administration Schedule; 00; Angiogenesis Inhibitors/administration & dosage/pharmacology; ARPE-19 cells; Cell encapsulation; Cell Line; Cell Survival/*physiology; Drug Delivery Systems; Hydrogel; Hydrogels; Pharmacokinetic/pharmacodynamic modeling; Recombinant protein; Retinal Diseases/drug therapy/pathology; Retinal neovascularization; Retinal Pigment Epithelium/*cytology; Vascular endothelial growth factor inhibitor; Vascular Endothelial Growth Factor Receptor-1/*secretion; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5X62YL73,journalArticle,2015,"Purtle, Jonathan; Rich, Linda J.; Bloom, Sandra L.; Rich, John A.; Corbin, Theodore J.",Cost-benefit analysis simulation of a hospital-based violence intervention program.,American journal of preventive medicine,,1873-2607 0749-3797,10.1016/j.amepre.2014.08.030,,"BACKGROUND: Violent injury is a major cause of disability, premature mortality, and health disparities worldwide. Hospital-based violence intervention programs (HVIPs) show promise in preventing violent injury. Little is known, however, about how the impact of HVIPs may translate into monetary figures. PURPOSE: To conduct a cost-benefit analysis simulation to estimate the savings an HVIP might produce in healthcare, criminal justice, and lost productivity costs over 5 years in a hypothetical population of 180 violently injured patients, 90 of whom received HVIP intervention and 90 of whom did not. METHODS: Primary data from 2012, analyzed in 2013, on annual HVIP costs/number of clients served and secondary data sources were used to estimate the cost, number, and type of violent reinjury incidents (fatal/nonfatal, resulting in hospitalization/not resulting in hospitalization) and violent perpetration incidents (aggravated assault/homicide) that this population might experience over 5 years. Four different models were constructed and three different estimates of HVIP effect size (20%, 25%, and 30%) were used to calculate a range of estimates for HVIP net savings and cost-benefit ratios from different payer perspectives. All benefits were discounted at 5% to adjust for their net present value. RESULTS: Estimates of HVIP cost savings at the base effect estimate of 25% ranged from $82,765 (narrowest model) to $4,055,873 (broadest model). CONCLUSIONS: HVIPs are likely to produce cost savings. This study provides a systematic framework for the economic evaluation of HVIPs and estimates of HVIP cost savings and cost-benefit ratios that may be useful in informing public policy decisions.",2015-02,26/11/2018 12:51,14/04/2020 08:35,,162-169,,2,48,,Am J Prev Med,,,,,,,,eng,Copyright (c) 2015 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.,,,,,,PMID: 25442223,,,,"Humans; United States; Cost-Benefit Analysis; Health Care Costs; Efficiency, Organizational; Cost Savings; 00; Secondary Prevention; *Hospitals; Criminal Law; Violence/*economics/*prevention & control; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HK9ZQFZK,journalArticle,2016,"Akroyd, Mike; Jordan, Gary; Rowlands, Paul","Interprofessional, simulation-based technology-enhanced learning to improve physical health care in psychiatry: The recognition and assessment of medical problems in psychiatric settings course.",Health informatics journal,,1741-2811 1460-4582,10.1177/1460458214557098,,"People with serious mental illness have reduced life expectancy compared with a control population, much of which is accounted for by significant physical comorbidity. Frontline clinical staff in mental health often lack confidence in recognition, assessment and management of such 'medical' problems. Simulation provides one way for staff to practise these skills in a safe setting. We produced a multidisciplinary simulation course around recognition and assessment of medical problems in psychiatric settings. We describe an audit of strategic and design aspects of the recognition and assessment of medical problems in psychiatric settings course, using the Department of Health's 'Framework for Technology Enhanced Learning' as our audit standards. At the same time as highlighting areas where recognition and assessment of medical problems in psychiatric settings adheres to these identified principles, such as the strategic underpinning of the approach, and the means by which information is collected, reviewed and shared, it also helps us to identify areas where we can improve.",2016-06,26/11/2018 12:51,14/04/2020 08:34,,312-320,,2,22,,Health Informatics J,,,,,,,,eng,(c) The Author(s) 2014.,,,,,,PMID: 25425630,,,,Humans; Health Personnel/education; Simulation Training/*methods; *Interprofessional Relations; 00; *Comorbidity; *clinical decision-making; *collaborative work practices and IT; *e-learning; *health-care professional training; *Psychiatry; *quality control; Clinical Decision-Making; Mental Disorders; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IY3AMRMZ,journalArticle,2014,"Gomez, Jorge Alberto; Lepetic, Alejandro; Demarteau, Nadia",Health economic analysis of human papillomavirus vaccines in women of Chile: perspective of the health care payer using a Markov model.,BMC public health,,1471-2458 1471-2458,10.1186/1471-2458-14-1222,,"BACKGROUND: In Chile, significant reductions in cervical cancer incidence and mortality have been observed due to implementation of a well-organized screening program. However, it has been suggested that the inclusion of human papillomavirus (HPV) vaccination for young adolescent women may be the best prospect to further reduce the burden of cervical cancer. This cost-effectiveness study comparing two available HPV vaccines in Chile was performed to support decision making on the implementation of universal HPV vaccination. METHODS: The present analysis used an existing static Markov model to assess the effect of screening and vaccination. This analysis includes the epidemiology of low-risk HPV types allowing for the comparison between the two vaccines (HPV-16/18",26/11/2014,26/11/2018 12:51,14/04/2020 08:34,,1222,,,14,,BMC Public Health,,,,,,,,eng,,,,,,,PMID: 25424716 PMCID: PMC4289178,,,,"Humans; Quality-Adjusted Life Years; Female; *Cost-Benefit Analysis; Markov Chains; Child; *Health Care Costs; Models, Theoretical; Costs and Cost Analysis; Chile; Vaccination/*economics; 1; Adjuvants, Immunologic/economics; Alphapapillomavirus/*immunology; Cross Protection; Human papillomavirus 11/immunology; Human papillomavirus 16/immunology; Human papillomavirus 18/immunology; Human papillomavirus 6/immunology; Papillomavirus Infections/*economics/prevention & control/virology; Papillomavirus Vaccines/*economics; Uterine Cervical Neoplasms/*economics/prevention & control/virology; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, A4L5IM47,journalArticle,2015,"Kotsakis, Afrothite; Mercer, Karen; Mohseni-Bod, Hadi; Gaiteiro, Rose; Agbeko, Rachel",The development and implementation of an inter-professional simulation based pediatric acute care curriculum for ward health care providers.,Journal of interprofessional care,,1469-9567 1356-1820,10.3109/13561820.2014.984018,,"An interprofessional, simulation based, acute care course for ward health care providers was developed and implemented with the objectives of teaching identification of deteriorating patients, practicing crisis resource management and basic life support skills, and using the SBAR (Situation Background Assessment Recommendation) communication tool. Thirty-eight physicians and 51 nurses attended the four separate courses. Nine questions on a 5-point Likert scale and two open-ended questions revealed that over 95% of respondents strongly agreed/agreed that facilitators encouraged active participation, lectures were presented in an interesting manner, and that simulations were useful for practical skills and for practicing communication. Open-ended questions revealed that participants felt more confident, understood the importance of communication, roles, teamwork and valued the day. Based on this evaluation, the program was regarded as feasible and acceptable to all health care providers.",2015,26/11/2018 12:51,14/04/2020 08:34,,392-394,,4,29,,J Interprof Care,,,,,,,,eng,,,,,,,PMID: 25421455,,,,"Humans; Program Evaluation; Clinical Competence; Curriculum; Communication; *Interprofessional Relations; Patient Care Team/*organization & administration; Inservice Training; simulation; 00; Simulation Training/*organization & administration; Pediatrics/*education; survey; interprofessional education; Crisis resource management; Internship and Residency/organization & administration; Life Support Care/*organization & administration; Nursing Staff, Hospital/education; resuscitation; SBAR; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GZMGZY8S,journalArticle,2014,"Peersman, Geert; Jak, Wouter; Vandenlangenbergh, Tom; Jans, Christophe; Cartier, Philippe; Fennema, Peter",Cost-effectiveness of unicondylar versus total knee arthroplasty: a Markov model analysis.,The Knee,,1873-5800 0968-0160,10.1016/S0968-0160(14)50008-7,,"BACKGROUND: Unicondylar knee arthroplasty (UKA) is believed to lead to less morbidity and enhanced functional outcomes when compared with total knee arthroplasty (TKA). Conversely, UKA is also associated with a higher revision risk than TKA. In order to further clarify the key differences between these separate procedures, the current study assessing the cost-effectiveness of UKA versus TKA was undertaken. METHODS: A state-transition Markov model was developed to compare the cost-effectiveness of UKA versus TKA for unicondylar osteoarthritis using a Belgian payer's perspective. The model was designed to include the possibility of two revision procedures. Model estimates were obtained through literature review and revision rates were based on registry data. Threshold analysis and probabilistic sensitivity analysis were performed to assess the model's robustness. RESULTS: UKA was associated with a cost reduction of euro2,807 and a utility gain of 0.04 quality-adjusted life years in comparison with TKA. Analysis determined that the model is sensitive to clinical effectiveness, and that a marginal reduction in the clinical performance of UKA would lead to TKA being the more cost-effective solution. CONCLUSION: UKA yields clear advantages in terms of costs and marginal advantages in terms of health effects, in comparison with TKA.",2014,26/11/2018 12:51,14/04/2020 08:35,,S37-42,,,21 Suppl 1,,Knee,,,,,,,,eng,(c) 2014 Elsevier B.V. All rights reserved.,,,,,,PMID: 25382367,,,,"Humans; *Cost-Benefit Analysis; Markov Chains; Cost-effectiveness; Registries; Arthroplasty, Replacement, Knee/*economics; Knee; Knee Joint/*surgery; Osteoarthritis, Knee/*economics/surgery; Register; Reoperation/*economics/statistics & numerical data; Total knee arthroplasty; Unicondylar knee arthroplasty; 00; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, T6YQWK6V,journalArticle,2014,"Shearer, Jessica C.; Dion, Michelle; Lavis, John N.",Exchanging and using research evidence in health policy networks: a statistical network analysis.,Implementation science : IS,,1748-5908 1748-5908,10.1186/s13012-014-0126-8,,"BACKGROUND: Evidence-informed health policymaking is a goal of equitable and effective health systems but occurs infrequently in reality. Past research points to the facilitating role of interpersonal relationships between policy-makers and researchers, imploring the adoption of a social network lens. This study aims to identify network-level factors associated with the exchange and use of research evidence in policymaking. METHODS: Data on social networks and research use were collected from seventy policy actors across three health policy cases in Burkina Faso (child health, malaria, and HIV). Networks were graphed for actors' interactions, their provision of, and request for research evidence. Exponential random graph models estimated the probability of evidence provision and request between actors, controlling for network- and individual-level covariates. Logistic regression models estimated actors' use of research evidence to inform policy. RESULTS: Network structure explained more than half of the evidence exchanges (ties) observed in these networks. Across all cases, a pair of actors was more likely to form a provision tie if they already had a request tie between them and visa versa (theta=6.16, p<0.05; theta=2.87, p<0.05; theta=2.31, p<0.05). The child health network displayed clustering tendencies, meaning that actors were more likely to form ties if they shared an acquaintance (theta=2.36, p<0.05). Actors' use of research evidence was positively associated with their centrality (i.e., connectedness). CONCLUSIONS: The exchange and use of research evidence in policymaking can be partly explained by the structure of actors' networks of relationships. Efforts to support knowledge translation and evidence-informed policymaking should consider network factors.",30/10/2014,26/11/2018 12:51,14/04/2020 08:35,,126,,,9,,Implement Sci,,,,,,,,eng,,,,,,,PMID: 25358894 PMCID: PMC4226903,,,,"*Health Policy; Humans; Child; Models, Statistical; Data Collection; Social Support; *Policy Making; 1; Network analysis; Administrative Personnel/statistics & numerical data; Child Health Services/statistics & numerical data; Evidence-Based Practice/*statistics & numerical data; Health Services Research/organization & administration/*utilization; Malaria/prevention & control; Translational Medical Research/*statistics & numerical data; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, M4DYTZNA,journalArticle,2015,"Butt, Thomas; Crossland, Michael D.; West, Peter; Orr, Shepley W.; Rubin, Gary S.",Simulation contact lenses for AMD health state utility values in NICE appraisals: a different reality.,The British journal of ophthalmology,,1468-2079 0007-1161,10.1136/bjophthalmol-2014-305802,,"BACKGROUND/AIMS: The National Institute for Health and Care Excellence (NICE) has recommended the use of ranibizumab for neovascular age-related macular degeneration (AMD) and for diabetic macular oedema (DMO) as part of its health technology appraisal process. In the economic evaluations of both interventions, utility values were derived from members of the general public wearing contact lenses with a central opacity that was meant to simulate the blind spot experienced by many patients with advanced retinal disease. This paper tests the validity of the contact lens simulation, and finding it to be invalid, explores the impact on prior economic evaluations. METHODS: Visual acuity, contrast sensitivity and visual fields were assessed with and without simulation lenses in five healthy subjects with normal vision. RESULTS: We identified important differences between the contact lens simulation and vision loss experienced by patients with AMD. The contact lens simulator did not cause the central scotoma which is characteristic of late-stage AMD and which leads to severe difficulty with everyday activities such as reading or recognising faces and objects. The contact lens instead caused a reduction in retinal illumination experienced by the subjects as a general dimming across the retina. CONCLUSIONS: A contact lens with a central opacity does not simulate a central scotoma. The clinical differences between simulated and actual AMD suggest there has been an underestimation of the severity of AMD health states. This brings into question the validity of the economic evaluations of treatments for AMD and DMO used by NICE.",2015-04,26/11/2018 12:51,14/04/2020 08:34,,540-544,,4,99,,Br J Ophthalmol,,,,,,,,eng,Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.,,,,,,PMID: 25351679 PMCID: PMC4392203,,,,"Humans; Health Status Indicators; *Models, Biological; Quality of Life; State Medicine; 00; *Contact Lenses, Hydrophilic; Contrast Sensitivity/*physiology; Healthy Volunteers; Macular Degeneration/*physiopathology; Retina; Retina/physiology; Vision; Vision Disorders/*physiopathology; Visual Acuity/*physiology; Visual Field Tests; Visual Fields/*physiology; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, AWDYF3YP,journalArticle,2015,"Lafeuille, Marie-Helene; Grittner, Amanda Melina; Gravel, Jonathan; Bailey, Robert A.; Martin, Silas; Garber, Lawrence; Duh, Mei Sheng; Lefebvre, Patrick",Economic simulation of canagliflozin and sitagliptin treatment outcomes in patients with type 2 diabetes mellitus with inadequate glycemic control.,Journal of medical economics,,1941-837X 1369-6998,10.3111/13696998.2014.980503,,"OBJECTIVES: This study examines the association between changes in diabetes-related quality measures (QMs) (HbA1c, systolic and diastolic blood pressure [BP], low-density lipoprotein cholesterol [LDL-C], and body weight) and healthcare costs in Type 2 diabetes mellitus (T2DM) patients. It also performs an economic simulation that evaluates the cost implications of the changes in QMs and of the incidence rates (IRs) of adverse events (AEs) associated with canagliflozin (CANA) and sitagliptin (SITA) treatments in a real-world setting. METHODS: Health-insurance claims and electronic medical records from the Reliant Medical Group database (2007-2011) were used to identify adult patients with T2DM receiving metformin and sulfonylurea who did not achieve adequate glycemic control. The association between the changes in QMs and healthcare costs was evaluated using multivariate regression and non-parametric bootstrap methods.",2015-02,26/11/2018 12:51,14/04/2020 08:34,,113-125,,2,18,,J Med Econ,,,,,,,,eng,,,,,,,PMID: 25350645,,,,"Humans; Quality Indicators, Health Care; Adult; Female; Male; Middle Aged; Young Adult; Aged; Adolescent; Comorbidity; Computer Simulation; Costs and Cost Analysis; *Models, Econometric; Blood Glucose; Blood Pressure; 00; Blood pressure; Body Weight; Canagliflozin; Canagliflozin/*economics/therapeutic use; Cholesterol, LDL; Diabetes Mellitus, Type 2/complications/*drug therapy; Glycated Hemoglobin A; HbA1c; Healthcare costs; Hypoglycemic Agents/*economics/therapeutic use; Insurance Claim Review; LDL-C; Sitagliptin; Sitagliptin Phosphate/*economics/therapeutic use; Type 2 diabetes mellitus; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 47DKWEHH,journalArticle,2015,"Baccini, Michela; Grisotto, Laura; Catelan, Dolores; Consonni, Dario; Bertazzi, Pier Alberto; Biggeri, Annibale",Commuting-adjusted short-term health impact assessment of airborne fine particles with uncertainty quantification via Monte Carlo simulation.,Environmental health perspectives,,1552-9924 0091-6765,10.1289/ehp.1408218,,"BACKGROUND: Exposure to air pollution is associated with a short-term increase in mortality, and this field has begun to focus on health impact assessment. OBJECTIVES: Our aim was to estimate the impact of PM10 on mortality within 2 days from the exposure in the Italian region of Lombardy for the year 2007, at the municipality level, examining exposure entailed by daily intermunicipality commuting and accounting for uncertainty propagation. METHODS: We combined data from different sources to derive probabilistic distributions for all input quantities used to calculate attributable deaths (mortality rates, PM10 concentrations, estimated PM10 effects, and commuting flows) and applied a Monte Carlo procedure to propagate uncertainty and sample the distribution of attributable deaths for each municipality. RESULTS: We estimated that annual average PM10 concentrations above the World Health Organization-recommended threshold of 20 mug/m3 were responsible for 865 short-term deaths (80% credibility interval: 475, 1,401), 26% of which were attributable to PM10 above the European Union limit of 40 mug/m3. Reducing annual average PM10 concentrations > 20 mug/m3 by 20% would have reduced the number of attributable deaths by 36%. The largest estimated impacts were along the basin of the Po River and in the largest cities. Commuting contributed to the spatial distribution of the estimated impact. CONCLUSIONS: Our estimates, which incorporated uncertainty quantification, indicate that the short-term impact of PM10 on mortality in Lombardy in 2007 was notable, and that reduction in air pollution would have had a substantial beneficial effect on population health. Using commuting data helped to identify critical areas for prioritizing intervention.",2015-01,26/11/2018 12:51,14/04/2020 08:34,,27-33,,1,123,,Environ Health Perspect,,,,,,,,eng,,,,,,,PMID: 25325518 PMCID: PMC4286278,,,,Humans; Monte Carlo Method; Mortality; 00; *Health Impact Assessment; *Transportation; Air Pollutants/*adverse effects/analysis; Air Pollution/*adverse effects/analysis; Italy/epidemiology; Particulate Matter/*adverse effects/analysis; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DCHMZYGJ,journalArticle,2014,"Moulsdale, Hilary J.; Khetsuriani, Nino; Deshevoi, Sergei; Butler, Robb; Simpson, John; Salisbury, David",Simulation exercises to strengthen polio outbreak preparedness: experience of the World Health Organization European Region.,The Journal of infectious diseases,,1537-6613 0022-1899,10.1093/infdis/jiu120,,"BACKGROUND: Poliovirus importations and related outbreaks continue to occur in polio-free countries, including those in the World Health Organization (WHO) European Region. National preparedness plans for responding to poliovirus introduction are insufficient in many countries of the European Region. We describe a series of polio outbreak simulation exercises that were implemented to formally test polio outbreak preparedness plans in the European Region. METHODS: We designed and implemented the exercises, reviewed the results, made recommendations, and assessed the role of outbreak simulation exercises in maintaining regional polio-free status. In addition, we performed a comprehensive review of the national plans of all WHO Member States in the European Region. RESULTS: Three exercises, delivered during 2011-2013 (for the Balkans, United Kingdom, and the Caucasus and Ukraine), revealed that participating countries were generally prepared for poliovirus introduction, but the level of preparedness needed improvement. The areas in particular need of strengthening were national preparedness plans, initial response, plans for securing vaccine supply, and communications. CONCLUSIONS: Polio outbreak simulation exercises can be valuable tools to help maintain polio-free status and should be extended to other high-risk countries and subnational areas in the European Region and elsewhere.",01/11/2014,26/11/2018 12:51,14/04/2020 08:35,,S208-215,,,210 Suppl 1,,J Infect Dis,,,,,,,,eng,"(c) The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.",,,,,,PMID: 25316837,,,,Humans; World Health Organization; *Computer Simulation; *Disease Outbreaks; Europe/epidemiology; *Health Services Research; 00; Civil Defense/*methods; polio eradication; polio outbreak simulation exercise (POSE); Poliomyelitis/*epidemiology/*prevention & control; poliovirus; preparedness exercise; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ISZCPB4V,journalArticle,2014,"Wieland, Diane; Levine, Ciara; Smith, Janet","Hearing distressing voices clinical simulation: ""life changing"" experiences of psychiatric-mental health nursing students.",Journal of psychosocial nursing and mental health services,,0279-3695 0279-3695,10.3928/02793695-20140911-01,,"The purpose of the current qualitative study was to investigate the experience of baccalaureate nursing (BSN) students with the clinical simulation of hearing distressing voices and derive themes from the written reflective data of students' evaluative statements. A purposive convenience sample of BSN students (N = 74) was recruited from two nursing cohorts at a private, religiously affiliated university BSN program in the northeastern United States. Student reflections on three evaluation questions of the simulation experience were analyzed using constant comparison as per naturalistic inquiry methodology. Themes emerged from each of the three questions related to students' experiences of hearing the simulated voices. Findings support the value of this simulation as a means to promote both active and affective learning in BSN students as they enter psychiatric-mental health clinical rotations.",2014-10,26/11/2018 12:51,14/04/2020 08:35,,42-51,,10,52,,J Psychosoc Nurs Ment Health Serv,,,,,,,,eng,"Copyright 2014, SLACK Incorporated.",,,,,,PMID: 25291728,,,,"Humans; Adult; Female; Male; Nursing Education Research; Young Adult; *Patient Simulation; Cohort Studies; Psychiatric Nursing/*education; Education, Nursing, Baccalaureate/*methods; *Students, Nursing; Education, Nursing, Continuing; Teaching/*methods; 00; Hallucinations/*diagnosis/*nursing; New England; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Z3PTKI6B,journalArticle,2014,"Yang, Kyeongra; Woomer, Gail Ratliff; Agbemenu, Kafuli; Williams, Lynne",Relate better and judge less: poverty simulation promoting culturally competent care in community health nursing.,Nurse education in practice,,1873-5223 1471-5953,10.1016/j.nepr.2014.09.001,,"The study aim was to evaluate the effectiveness of a poverty simulation in increasing understanding of and attitudes toward poverty and resulting in changes in clinical practice among nursing seniors. A poverty simulation was conducted using a diverse group of nursing professors and staff from local community agencies assuming the role of community resource providers. Students were assigned roles as members of low-income families and were required to complete tasks during a simulated month. A debriefing was held after the simulation to explore students' experiences in a simulated poverty environment. Students' understanding of and attitude toward poverty pre- and post-simulation were examined. Changes in the students' clinical experiences following the simulation were summarized into identified categories and themes. The poverty simulation led to a greater empathy for the possible experiences of low income individuals and families, understanding of barriers to health care, change in attitudes towards poverty and to those living in poverty, and changes in the students' nursing practice. Use of poverty simulation is an effective means to teach nursing students about the experience of living in poverty. The simulation experience changed nursing students' clinical practice, with students providing community referrals and initiating inter-professional collaborations.",2014-11,26/11/2018 12:51,14/04/2020 08:35,,680-685,,6,14,,Nurse Educ Pract,,,,,,,,eng,Copyright (c) 2014 Elsevier Ltd. All rights reserved.,,,,,,PMID: 25262065,,,,"Humans; Surveys and Questionnaires; United States; *Patient Simulation; Education, Nursing, Continuing; Community Health Nursing/*education; *Nurse-Patient Relations; 00; *Poverty Areas; Community health nursing; *Culturally Competent Care; Cultural competency; Poverty simulation; Teaching/methods; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HIM5RGTP,journalArticle,2014,"Goodall, K. T.; Newman, L. A.; Ward, P. R.",Improving access to health information for older migrants by using grounded theory and social network analysis to understand their information behaviour and digital technology use.,European journal of cancer care,,1365-2354 0961-5423,10.1111/ecc.12241,,"Migrant well-being can be strongly influenced by the migration experience and subsequent degree of mainstream language acquisition. There is little research on how older Culturally And Linguistically Diverse (CALD) migrants who have 'aged in place' find health information, and the role which digital technology plays in this. Although the research for this paper was not focused on cancer, we draw out implications for providing cancer-related information to this group. We interviewed 54 participants (14 men and 40 women) aged 63-94 years, who were born in Italy or Greece, and who migrated to Australia mostly as young adults after World War II. Constructivist grounded theory and social network analysis were used for data analysis. Participants identified doctors, adult children, local television, spouse, local newspaper and radio as the most important information sources. They did not generally use computers, the Internet or mobile phones to access information. Literacy in their birth language, and the degree of proficiency in understanding and using English, influenced the range of information sources accessed and the means used. The ways in which older CALD migrants seek and access information has important implications for how professionals and policymakers deliver relevant information to them about cancer prevention, screening, support and treatment, particularly as information and resources are moved online as part of e-health.",2014-11,26/11/2018 12:51,14/04/2020 08:34,,728-738,,6,23,,Eur J Cancer Care (Engl),,,,,,,,eng,(c) 2014 John Wiley & Sons Ltd.,,,,,,PMID: 25250535,,,,"Humans; Female; Male; Middle Aged; Aged; Aged, 80 and over; Australia; social network analysis; 00; Neoplasms/*therapy; Information Dissemination/methods; *Grounded Theory; *Transients and Migrants; Access to Information; CALD; Consumer Health Information/*utilization; e-health; Greece/ethnology; grounded theory; Information Systems/*utilization; Italy/ethnology; migrants; older people; Social Networking; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YGSQDMV8,journalArticle,2015,"Watson, Penny; Brennan, Alan; Birch, Helen; Fang, Hong; Petri, Michelle",An integrated extrapolation of long-term outcomes in systemic lupus erythematosus: analysis and simulation of the Hopkins lupus cohort.,"Rheumatology (Oxford, England)",,1462-0332 1462-0324,10.1093/rheumatology/keu375,,"OBJECTIVE: The aim of this study was to develop an SLE disease model that simulates long-term outcomes of SLE to estimate the long-term effectiveness and cost-effectiveness of SLE treatments. METHODS: Longitudinal data from 1354 patients from the Hopkins Lupus Cohort were included in the analysis. Statistical models were created to estimate disease activity [Safety of Estrogen in Lupus Erythematosus National Assessment (SELENA) SLEDAI scale] and prednisone dose over time using linear regression. Survival models for organ damage and mortality were created. The models were combined in a predictive simulation of SLE organ damage and mortality. Predictions were assessed against the Hopkins Lupus Cohort data. RESULTS: The analyses found that change in the annual average SLEDAI score was associated with the previous annual average SLEDAI score, renal involvement, age, male gender, African American ethnicity, anaemia, haematological involvement, increased DNA binding and low complement. The annual average prednisone dose increased for every unit increase in annual average SLEDAI. Organ damage and mortality modelling demonstrated that adjusted mean SLEDAI and binary SLEDAI organ involvement indicators predicted mortality, cardiovascular, renal, neuropsychiatric, pulmonary, gastrointestinal, ocular and skin damage. The cumulative average prednisone dose was associated with risk of cardiovascular, ocular, musculoskeletal, neuropsychiatric and gastrointestinal damage, gonadal failure and diabetes mellitus. The simulation reproduced mean SLEDAI and organ damage scores from the Hopkins Lupus Cohort. CONCLUSION: Longitudinal modelling of an SLE cohort confirmed relationships between risk factors and long-term outcomes in SLE. The models serve to estimate the probability of SLE outcomes over time and can be used to estimate the effectiveness and cost-effectiveness of new treatments.",2015-04,26/11/2018 12:51,14/04/2020 08:35,,623-632,,4,54,,Rheumatology (Oxford),,,,,,,,eng,"(c) The Author 2014. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.",,,,,,PMID: 25234659,,,,"Humans; Outcome Assessment (Health Care); Cost-Benefit Analysis; Adult; Female; Male; Middle Aged; Cohort Studies; *Health Care Costs; Severity of Illness Index; health economics; Models, Statistical; Linear Models; Prospective Studies; Longitudinal Studies; epidemiology; Sex Factors; Survival Analysis; 00; African Americans; Anemia/etiology/*therapy; European Continental Ancestry Group; health outcomes; Immunosuppressive Agents/economics/*therapeutic use; Lupus Erythematosus, Systemic/complications/*drug therapy/mortality; Lupus Nephritis/etiology/*therapy; Prednisone/economics/*therapeutic use; statistics; systemic lupus erythematosus; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EIS3LFS7,journalArticle,2016,"Dorjee, S.; Revie, C. W.; Poljak, Z.; McNab, W. B.; McClure, J. T.; Sanchez, J.",One-Health Simulation Modelling: Assessment of Control Strategies Against the Spread of Influenza between Swine and Human Populations Using NAADSM.,Transboundary and emerging diseases,,1865-1682 1865-1674,10.1111/tbed.12260,,"Simulation models implemented using a range of parameters offer a useful approach to identifying effective disease intervention strategies. The objective of this study was to investigate the effects of key control strategies to mitigate the simultaneous spread of influenza among and between swine and human populations. We used the pandemic H1N1 2009 virus as a case study. The study population included swine herds (488 herds) and households-of-people (29,707 households) within a county in Ontario, Canada. Households were categorized as: (i) rural households with swine workers, (ii) rural households without swine workers and (iii) urban households without swine workers. Seventy-two scenarios were investigated based on a combination of the parameters of speed of detection and control strategies, such as quarantine strategy, effectiveness of movement restriction and ring vaccination strategy, all assessed at three levels of transmissibility of the virus at the swine-human interface. Results showed that the speed of detection of the infected units combined with the quarantine strategy had the largest impact on the duration and size of outbreaks. A combination of fast to moderate speed of the detection (where infected units were detected within 5-10 days since first infection) and quarantine of the detected units alone contained the outbreak within the swine population in most of the simulated outbreaks. Ring vaccination had no added beneficial effect. In conclusion, our study suggests that the early detection (and therefore effective surveillance) and effective quarantine had the largest impact in the control of the influenza spread, consistent with earlier studies. To our knowledge, no study had previously assessed the impact of the combination of different intervention strategies involving the simultaneous spread of influenza between swine and human populations.",2016-04,26/11/2018 12:51,14/04/2020 08:34,,e229-244,,2,63,,Transbound Emerg Dis,,,,,,,,eng,(c) 2014 Blackwell Verlag GmbH.,,,,,,PMID: 25219283,,,,"Humans; Disease Management; Models, Theoretical; Quarantine; Animals; Communicable Disease Control/*methods; Rural Population; 00; Urban Population; Ontario/epidemiology; *Influenza, Human/epidemiology/prevention & control/virology; Agricultural Workers' Diseases/prevention & control/virology; Disease Outbreaks/*prevention & control/veterinary; humans; influenza; Influenza A Virus, H1N1 Subtype/isolation & purification; modelling; NAADSM; one-health; Orthomyxoviridae Infections/*epidemiology/transmission/veterinary; pigs; Swine; Swine Diseases/epidemiology/prevention & control/*virology; Vaccination/veterinary; zoonotic diseases; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7FWFP9UV,journalArticle,2014,"McAnany, Steven J.; Overley, Samuel; Baird, Evan O.; Cho, Samuel K.; Hecht, Andrew C.; Zigler, Jack E.; Qureshi, Sheeraz A.",The 5-year cost-effectiveness of anterior cervical discectomy and fusion and cervical disc replacement: a Markov analysis.,Spine,,1528-1159 0362-2436,10.1097/BRS.0000000000000562,,"STUDY DESIGN: A Markov state-transition model was developed to evaluate the cost-effectiveness of anterior cervical discectomy and fusion (ACDF) and cervical disc replacement (CDR) at 5 years. OBJECTIVE: To determine the cost-effectiveness of ACDF and CDR at 5 years. SUMMARY OF BACKGROUND DATA: ACDF and CDR are surgical options for the treatment of an acute cervical disc herniation with associated myelopathy/radiculopathy. Cost-effectiveness analysis provides valuable information regarding which intervention will lead to a more efficient utilization of health care resources. METHODS: Outcome and complication probabilities were obtained from existing literature. Physician costs were based on a fixed percentage of 140% of 2010 Medicare reimbursement. Hospital costs were determined from the Nationwide Inpatient Sample. Utilities were derived from responses to health state surveys (Short Form 36) at baseline and at 5 years from the treatment arms of the ProDisc-C trial. Incremental cost-effectiveness ratios were used to compare treatments. One-way sensitivity analyses were performed on all parameters within the model. RESULTS: CDR generated a total 5-year cost of $102,274, whereas ACDF resulted in a 5-year cost of $119,814. CDR resulted in a generation of 2.84 quality-adjusted life years, whereas ACDF resulted in 2.81. The incremental cost-effectiveness ratio was -$557,849 per quality-adjusted life year gained. CDR remained the dominant strategy below a cost of $20,486. ACDF was found to be a cost-effective strategy below a cost of $18,607. CDR was the dominant strategy when the utility value was above 0.713. CDR remained the dominant strategy assuming an annual complication rate less than 4.37%. CONCLUSION: ACDF and CDR were both shown to be cost-effective strategies at 5 years. CDR was found to be the dominant treatment strategy in our model. Further long-term studies evaluating the clinical and quality-of-life outcomes of these 2 treatments are needed to further validate the model. LEVEL OF EVIDENCE: 5.",01/11/2014,26/11/2018 12:51,14/04/2020 08:34,,1924-1933,,23,39,,Spine (Phila Pa 1976),,,,,,,,eng,,,,,,,PMID: 25188602,,,,Humans; Treatment Outcome; Adult; Female; Male; *Markov Chains; Time Factors; *Cervical Vertebrae/surgery; Cost-Benefit Analysis/*economics/trends; Diskectomy/*economics/trends; Intervertebral Disc Displacement/*economics/surgery; Spinal Fusion/*economics/trends; 00; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4IMDXFDY,journalArticle,2015,"Hollingsworth, John M.; Funk, Russell J.; Owen-Smith, Jason; Landon, Bruce E.; Hollenbeck, Brent K.; Birkmeyer, John D.",Assessing the reach of health reform to outpatient surgery with social network analysis.,Annals of surgery,,1528-1140 0003-4932,10.1097/SLA.0000000000000880,,"OBJECTIVE: To assess the proportion of outpatient surgery currently delivered in ambulatory surgery centers (ASCs) unconnected to nearby hospitals. BACKGROUND: The ASC as a site for outpatient surgery represents one of the fastest growing sectors in health care. Because most are freestanding, ASCs may have little connection to local health systems, possibly placing them outside health reform's reach. METHODS: Using all-payer data from Florida (2005-2009), we identified all ASCs and hospitals active in the state. Using the tools of social network analysis, we then measured each ASC's strength of connection to nearby hospitals on the basis of the number of surgeons shared between facilities. Finally, we determined the proportion of all procedures and charges accounted for by (1) ASCs that are strongly connected to their local health system, (2) those that are weakly connected, and (3) those that are unconnected. RESULTS: Of the 1.4 million procedures performed in Florida ASCs each year, fewer than 250,000 occur at unconnected and weakly connected ASCs. Put differently, 83% of the $4.3 billion in charges for ASC-based care originate from facilities that have substantial integration with their local health system. Although weakly and strongly connected ASCs are similar from an organizational perspective, unconnected ones tend to focus on a single specialty (P = 0.026) and are staffed by fewer physicians (P = 0.013). Furthermore, there is a trend toward fewer unconnected ASCs over time (P = 0.080). CONCLUSIONS: Most ASCs are strongly connected to their local health system. Thus, efforts to constrain spending should target population-based rates of surgery, not unconnected ASCs.",2015-03,26/11/2018 12:51,14/04/2020 08:34,,468-472,,3,261,,Ann Surg,,,,,,,,eng,,,,,,,PMID: 25185474,,,,*Health Care Reform; Humans; United States; Health Services Research; *Interinstitutional Relations; 1; Ambulatory Surgical Procedures/*economics; Florida; Surgicenters/*economics; Social Network Analysis; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GUS48XB7,journalArticle,2014,"Peters, David H.",The application of systems thinking in health: why use systems thinking?,Health research policy and systems,,1478-4505 1478-4505,10.1186/1478-4505-12-51,,"This paper explores the question of what systems thinking adds to the field of global health. Observing that elements of systems thinking are already common in public health research, the article discusses which of the large body of theories, methods, and tools associated with systems thinking are more useful. The paper reviews the origins of systems thinking, describing a range of the theories, methods, and tools. A common thread is the idea that the behavior of systems is governed by common principles that can be discovered and expressed. They each address problems of complexity, which is a frequent challenge in global health. The different methods and tools are suited to different types of inquiry and involve both qualitative and quantitative techniques. The paper concludes by emphasizing that explicit models used in systems thinking provide new opportunities to understand and continuously test and revise our understanding of the nature of things, including how to intervene to improve people's health.",26/08/2014,26/11/2018 12:51,14/04/2020 08:35,,51,,,12,,Health Res Policy Syst,,,,,,,,eng,,,,,,,PMID: 25160707 PMCID: PMC4245196,,,,"Humans; *Public Health; *Systems Analysis; *Delivery of Health Care; *Models, Theoretical; Global Health; *Systems Theory; *Health Services Research; 00; 100; ****more for intro",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 36ZKVPQS,journalArticle,2014,"Adam, Taghreed",Advancing the application of systems thinking in health.,Health research policy and systems,,1478-4505 1478-4505,10.1186/1478-4505-12-50,,,26/08/2014,26/11/2018 12:51,14/04/2020 08:34,,50,,,12,,Health Res Policy Syst,,,,,,,,eng,,,,,,,PMID: 25160646 PMCID: PMC4245197,,,,Humans; *Systems Analysis; *Delivery of Health Care; *Systems Theory; 00; *Health; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ZCWEBYWS,journalArticle,2014,"Varghese, Joe; Kutty, V. Raman; Paina, Ligia; Adam, Taghreed","Advancing the application of systems thinking in health: understanding the growing complexity governing immunization services in Kerala, India.",Health research policy and systems,,1478-4505 1478-4505,10.1186/1478-4505-12-47,,"BACKGROUND: Governing immunization services in a way that achieves and maintains desired population coverage levels is complex as it involves interactions of multiple actors and contexts. In one of the Indian states, Kerala, after routine immunization had reached high coverage in the late 1990s, it started to decline in some of the districts. This paper describes an application of complex adaptive systems theory and methods to understand and explain the phenomena underlying unexpected changes in vaccination coverage. METHODS: We used qualitative methods to explore the factors underlying changes in vaccination coverage in two districts in Kerala, one with high and one with low coverage. Content analysis was guided by features inherent to complex adaptive systems such as phase transitions, feedback, path dependence, and self-organization. Causal loop diagrams were developed to depict the interactions among actors and critical events that influenced the changes in vaccination coverage. RESULTS: We identified various complex adaptive system phenomena that influenced the change in vaccination coverage levels in the two districts. Phase transition describes how initial acceptability to vaccination is replaced by a resistance in northern Kerala, which involved new actors; actors attempting to regain acceptability and others who countered it created several feedback loops. We also describe how the authorities have responded to declining immunization coverage and its impact on vaccine acceptability in the context of certain highly connected actors playing disproportionate influence over household vaccination decisions.Theoretical exposition of our findings reveals the important role of trust in health workers and institutions that shape the interactions of actors leading to complex adaptive system phenomena. CONCLUSIONS: As illustrated in this study, a complex adaptive system lens helps to uncover the 'real' drivers for change. This approach assists researchers and decision makers to systematically explore the driving forces and factors in each setting and develop appropriate and timely strategies to address them. The study calls for greater consideration of dynamics of vaccine acceptability while formulating immunization policies and program strategies. The analytical approaches adopted in this study are not only applicable to immunization or Kerala but to all complex interventions, health systems problems, and contexts.",26/08/2014,26/11/2018 12:51,14/04/2020 08:35,,47,,,12,,Health Res Policy Syst,,,,,,,,eng,,,,,,,PMID: 25160531 PMCID: PMC4245198,,,,Humans; *Public Health; Qualitative Research; Trust; India; *Patient Acceptance of Health Care; 00; *Health Services; *Immunization; *Vaccination; Family Characteristics; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PG79ZHKV,journalArticle,2014,"Blanchet, Karl; Palmer, Jennifer; Palanchowke, Raju; Boggs, Dorothy; Jama, Ali; Girois, Susan",Advancing the application of systems thinking in health: analysing the contextual and social network factors influencing the use of sustainability indicators in a health system--a comparative study in Nepal and Somaliland.,Health research policy and systems,,1478-4505 1478-4505,10.1186/1478-4505-12-46,,"BACKGROUND: Health systems strengthening is becoming a key component of development agendas for low-income countries worldwide. Systems thinking emphasizes the role of diverse stakeholders in designing solutions to system problems, including sustainability. The objective of this paper is to compare the definition and use of sustainability indicators developed through the Sustainability Analysis Process in two rehabilitation sectors, one in Nepal and one in Somaliland, and analyse the contextual factors (including the characteristics of system stakeholder networks) influencing the use of sustainability data. METHODS: Using the Sustainability Analysis Process, participants collectively clarified the boundaries of their respective systems, defined sustainability, and identified sustainability indicators. Baseline indicator data was gathered, where possible, and then researched again 2 years later. As part of the exercise, system stakeholder networks were mapped at baseline and at the 2-year follow-up. We compared stakeholder networks and interrelationships with baseline and 2-year progress toward self-defined sustainability goals. Using in-depth interviews and observations, additional contextual factors affecting the use of sustainability data were identified. RESULTS: Differences in the selection of sustainability indicators selected by local stakeholders from Nepal and Somaliland reflected differences in the governance and structure of the present rehabilitation system. At 2 years, differences in the structure of social networks were more marked. In Nepal, the system stakeholder network had become more dense and decentralized. Financial support by an international organization facilitated advancement toward self-identified sustainability goals. In Somaliland, the small, centralised stakeholder network suffered a critical rupture between the system's two main information brokers due to competing priorities and withdrawal of international support to one of these. Progress toward self-defined sustainability was nil. CONCLUSIONS: The structure of the rehabilitation system stakeholder network characteristics in Nepal and Somaliland evolved over time and helped understand the changing nature of relationships between actors and their capacity to work as a system rather than a sum of actors. Creating consensus on a common vision of sustainability requires additional system-level interventions such as identification of and support to stakeholders who promote systems thinking above individual interests.",26/08/2014,26/11/2018 12:51,14/04/2020 08:34,,46,,,12,,Health Res Policy Syst,,,,,,,,eng,,,,,,,PMID: 25160035 PMCID: PMC4267142,,,,"Delivery of Health Care/*organization & administration; Humans; Health Policy; *Quality Indicators, Health Care; Nepal; *Interpersonal Relations; *Developing Countries; Politics; 00; *Organizations; Somalia; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QQX7IU8Q,journalArticle,2014,"Sarriot, Eric G.; Kouletio, Michelle; Jahan, Dr Shamim; Rasul, Izaz; Musha, Akm",Advancing the application of systems thinking in health: sustainability evaluation as learning and sense-making in a complex urban health system in Northern Bangladesh.,Health research policy and systems,,1478-4505 1478-4505,10.1186/1478-4505-12-45,,"BACKGROUND: Starting in 1999, Concern Worldwide Inc. (Concern) worked with two Bangladeshi municipal health departments to support delivery of maternal and child health preventive services. A mid-term evaluation identified sustainability challenges. Concern relied on systems thinking implicitly to re-prioritize sustainability, but stakeholders also required a method, an explicit set of processes, to guide their decisions and choices during and after the project. METHODS: Concern chose the Sustainability Framework method to generate creative thinking from stakeholders, create a common vision, and monitor progress. The Framework is based on participatory and iterative steps: defining (mapping) the local system and articulating a long-term vision, describing scenarios for achieving the vision, defining the elements of the model, and selecting corresponding indicators, setting and executing an assessment plan,, and repeated stakeholder engagement in analysis and decisions . Formal assessments took place up to 5 years post-project (2009). RESULTS: Strategic choices for the project were guided by articulating a collective vision for sustainable health, mapping the system of actors required to effect and sustain change, and defining different components of analysis. Municipal authorities oriented health teams toward equity-oriented service delivery efforts, strengthening of the functionality of Ward Health Committees, resource leveraging between municipalities and the Ministry of Health, and mitigation of contextual risks. Regular reference to a vision (and set of metrics (population health, organizational and community capacity) mitigated political factors. Key structures and processes were maintained following elections and political changes. Post-project achievements included the maintenance or improvement 5 years post-project (2009) in 9 of the 11 health indicator gains realized during the project (1999-2004). Some elements of performance and capacity weakened, but reductions in the equity gap achieved during the project were largely maintained post-project. CONCLUSIONS: Sustainability is dynamic and results from local systems processes, which can be strengthened through both implicit and explicit systems thinking steps applied with constancy of purpose.",26/08/2014,26/11/2018 12:51,14/04/2020 08:35,,45,,,12,,Health Res Policy Syst,,,,,,,,eng,,,,,,,PMID: 25159873 PMCID: PMC4245801,,,,"Humans; Female; Child; Pregnancy; Infant, Newborn; *Program Evaluation; Government Programs; Politics; 00; *Maternal Health Services; *Urban Population; *Child Health Services; *Delivery of Health Care/organization & administration; *Social Change; *Urban Health Services/organization & administration; Bangladesh; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PJKK3DTC,journalArticle,2014,"Zhang, Xiulan; Bloom, Gerald; Xu, Xiaoxin; Chen, Lin; Liang, Xiaoyun; Wolcott, Sara J.",Advancing the application of systems thinking in health: managing rural China health system development in complex and dynamic contexts.,Health research policy and systems,,1478-4505 1478-4505,10.1186/1478-4505-12-44,,"BACKGROUND: This paper explores the evolution of schemes for rural finance in China as a case study of the long and complex process of health system development. It argues that the evolution of these schemes has been the outcome of the response of a large number of agents to a rapidly changing context and of efforts by the government to influence this adaptation process and achieve public health goals. METHODS: The study draws on several sources of data including a review of official policy documents and academic papers and in-depth interviews with key policy actors at national level and at a sample of localities. RESULTS: The study identifies three major transition points associated with changes in broad development strategy and demonstrates how the adaptation of large numbers of actors to these contextual changes had a major impact on the performance of the health system. Further, it documents how the Ministry of Health viewed its role as both an advocate for the interests of health facilities and health workers and as the agency responsible for ensuring that government health system objectives were met. It is argued that a major reason for the resilience of the health system and its ability to adapt to rapid economic and institutional change was the ability of the Ministry to provide overall strategy leadership. Additionally, it postulates that a number of interest groups have emerged, which now also seek to influence the pathway of health system development. CONCLUSIONS: This history illustrates the complex and political nature of the management of health system development and reform. The paper concludes that governments will need to increase their capacity to analyze the health sector as a complex system and to manage change processes.",26/08/2014,26/11/2018 12:51,14/04/2020 08:35,,44,,,12,,Health Res Policy Syst,,,,,,,,eng,,,,,,,PMID: 25159726 PMCID: PMC4245849,,,,*Health Policy; Delivery of Health Care/*organization & administration; Humans; *Public Health; China; Leadership; Health; *Rural Population; Politics; 00; *Social Change; *Government Programs; *Rural Health Services; ******To read; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4TM6RR3Z,journalArticle,2014,"Malik, Asmat U.; Willis, Cameron D.; Hamid, Saima; Ulikpan, Anar; Hill, Peter S.",Advancing the application of systems thinking in health: advice seeking behavior among primary health care physicians in Pakistan.,Health research policy and systems,,1478-4505 1478-4505,10.1186/1478-4505-12-43,,"BACKGROUND: Using measles and tuberculosis as case examples, with a systems thinking approach, this study examines the human advice-seeking behavior of primary health care (PHC) physicians in a rural district of Pakistan. This study analyzes the degree to which the existing PHC system supports their access to human advice, and explores in what ways this system might be strengthened to better meet provider needs. METHODS: The study was conducted in a rural district of Pakistan and, with a cross-sectional study design, it employed a range of research methods, namely extensive document review for mapping existing information systems, social network analysis of physicians' advice-seeking practice, and key stakeholder interviews for an in-depth understanding of the experience of physicians. Illustrations were prepared for information flow mechanism, sociographs were generated for analyzing social networks, and content analysis of qualitative findings was carried out for in-depth interpretation of underlying meanings. RESULTS: The findings of this study reveal that non-availability of competent supervisory staff, a focus on improving performance indicators rather than clinical guidance, and a lack of a functional referral system have collectively created an environment in which PHC physicians have developed their own strategies to overcome these constraints. They are well aware of the human expertise available within and outside the district. However, their advice-seeking behavior was dependent upon existence of informal social interaction with the senior specialists. Despite the limitations of the system, the physicians proactively used their professional linkages to seek advice and also to refer patients to the referral center based on their experience and the facilities that they trusted. CONCLUSIONS: The absence of functional referral systems, limited effective linkages between PHC and higher levels of care, and a focus on programmatic targets rather than clinical care have each contributed to the isolation of physicians and reactive information seeking behavior. The study findings underscore the need for a functional information system comprising context sensitive knowledge management and translation opportunities for physicians working in PHC centers. Such an information system needs to link people and resources in ways that transcend geography and discipline, and that builds on existing expertise, interpersonal relationships, and trust.",26/08/2014,26/11/2018 12:51,14/04/2020 08:34,,43,,,12,,Health Res Policy Syst,,,,,,,,eng,,,,,,,PMID: 25159587 PMCID: PMC4245738,,,,Humans; Delivery of Health Care; *Interprofessional Relations; Cross-Sectional Studies; *Physicians; *Primary Health Care; *Information Seeking Behavior; Professional Competence; Pakistan; Rural Population; 00; Referral and Consultation; Rural Health Services; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, B4A7CAVS,journalArticle,2014,"Prashanth, Nuggehalli Srinivas; Marchal, Bruno; Devadasan, Narayanan; Kegels, Guy; Criel, Bart","Advancing the application of systems thinking in health: a realist evaluation of a capacity building programme for district managers in Tumkur, India.",Health research policy and systems,,1478-4505 1478-4505,10.1186/1478-4505-12-42,,"BACKGROUND: Health systems interventions, such as capacity-building of health workers, are implemented across districts in order to improve performance of healthcare organisations. However, such interventions often work in some settings and not in others. Local health systems could be visualised as complex adaptive systems that respond variously to inputs of capacity building interventions, depending on their local conditions and several individual, institutional, and environmental factors. We aim at demonstrating how the realist evaluation approach advances complex systems thinking in healthcare evaluation by applying the approach to understand organisational change within local health systems in the Tumkur district of southern India. METHODS: We collected data on several input, process, and outcome measures of performance of the talukas (administrative sub-units of the district) and explore the interplay between the individual, institutional, and contextual factors in contributing to the outcomes using qualitative data (interview transcripts and observation notes) and quantitative measures of commitment, self-efficacy, and supervision style. RESULTS: The talukas of Tumkur district responded differently to the intervention. Their responses can be explained by the interactions between several individual, institutional, and environmental factors. In a taluka with committed staff and a positive intention to make changes, the intervention worked through aligning with existing opportunities from the decentralisation process to improve performance. However, commitment towards the organisation was neither crucial nor sufficient. Committed staff in two other talukas were unable to actualise their intentions to improve organisational performance. In yet another taluka, the leadership was able to compensate for the lack of commitment. CONCLUSIONS: Capacity building of local health systems could work through aligning or countering existing relationships between internal (individual and organisational) and external (policy and socio-political environment) attributes of the organisation. At the design and implementation stage, intervention planners need to identify opportunities for such triggering alignments. Local health systems may differ in their internal configuration and hence capacity building programmes need to accommodate possibilities for change through different pathways. By a process of formulating and testing hypotheses, making critical comparisons, discovering empirical patterns, and monitoring their scope and extent, a realist evaluation enables a comprehensive assessment of system-wide change in health systems.",26/08/2014,26/11/2018 12:51,14/04/2020 08:35,,42,,,12,,Health Res Policy Syst,,,,,,,,eng,,,,,,,PMID: 25159487 PMCID: PMC4245764,,,,Humans; *Delivery of Health Care; *Health Personnel; *Leadership; *Program Evaluation; India; Government Programs; 00; *Capacity Building; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KQHK8GIN,journalArticle,2014,"Paina, Ligia; Bennett, Sara; Ssengooba, Freddie; Peters, David H.","Advancing the application of systems thinking in health: exploring dual practice and its management in Kampala, Uganda.",Health research policy and systems,,1478-4505 1478-4505,10.1186/1478-4505-12-41,,"BACKGROUND: Many full-time Ugandan government health providers take on additional jobs - a phenomenon called dual practice. We describe the complex patterns that characterize the evolution of dual practice in Uganda, and the local management practices that emerged in response, in five government facilities. An in-depth understanding of dual practice can contribute to policy discussions on improving public sector performance. METHODS: A multiple case study design with embedded units of analysis was supplemented by interviews with policy stakeholders and a review of historical and policy documents. Five facility case studies captured the perspective of doctors, nurses, and health managers through semi-structured in-depth interviews. A causal loop diagram illustrated interactions and feedback between old and new actors, as well as emerging roles and relationships. RESULTS: The causal loop diagram illustrated how feedback related to dual practice policy developed in Uganda. As opportunities for dual practice grew and the public health system declined over time, government providers increasingly coped through dual practice. Over time, government restrictions to dual practice triggered policy resistance and protest from government providers. Resulting feedback contributed to compromising the supply of government providers and, potentially, of service delivery outcomes. Informal government policies and restrictions replaced the formal restrictions identified in the early phases. In some instances, government health managers, particularly those in hospitals, developed their own practices to cope with dual practice and to maintain public sector performance. Management practices varied according to the health manager's attitude towards dual practice and personal experience with dual practice. These practices were distinct in hospitals. Hospitals faced challenges managing internal dual practice opportunities, such as those created by externally-funded research projects based within the hospital. Private wings' inefficiencies and strict fee schedule made them undesirable work locations for providers. CONCLUSIONS: Dual practice prevails because public and private sector incentives, non-financial and financial, are complementary. Local management practices for dual practice have not been previously documented and provide learning opportunities to inform policy discussions. Understanding how dual practice evolves and how it is managed locally is essential for health workforce policy, planning, and performance discussions in Uganda and similar settings.",18/08/2014,26/11/2018 12:51,14/04/2020 08:35,,41,,,12,,Health Res Policy Syst,,,,,,,,eng,,,,,,,PMID: 25134522 PMCID: PMC4142472,,,,*Health Policy; Humans; *Public Health; *Attitude of Health Personnel; Motivation; Animals; Nurses; Physicians; 00; Workplace; *Health Facilities; Uganda; *Private Sector; Delivery of Health Care/manpower/*organization & administration; Public Sector/manpower/*organization & administration; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Z3SK2JHP,journalArticle,2014,"Kroelinger, Charlan D.; Rankin, Kristin M.; Chambers, David A.; Diez Roux, Ana V.; Hughes, Karen; Grigorescu, Violanda",Using the principles of complex systems thinking and implementation science to enhance maternal and child health program planning and delivery.,Maternal and child health journal,,1573-6628 1092-7875,10.1007/s10995-014-1586-9,,"Traditionally, epidemiologic methodologies have focused on measurement of exposures, outcomes, and program impact through reductionistic, yet complex statistical modeling. Although not new to the field of epidemiology, two frameworks that provide epidemiologists with a foundation for understanding the complex contexts in which programs and policies are implemented were presented to maternal and child health (MCH) professionals at the 2012 co-hosted 18th Annual MCH Epidemiology Conference and 22nd CityMatCH Urban Leadership Conference. The complex systems approach offers researchers in MCH the opportunity to understand the functioning of social, medical, environmental, and behavioral factors within the context of implemented public health programs. Implementation science provides researchers with a framework to translate the evidence-based program interventions into practices and policies that impact health outcomes. Both approaches offer MCH epidemiologists conceptual frameworks with which to re-envision how programs are implemented, monitored, evaluated, and reported to the larger public health audience. By using these approaches, researchers can begin to understand and measure the broader public health context, account for the dynamic interplay of the social environment, and ultimately, develop more effective MCH programs and policies.",2014-09,26/11/2018 12:51,14/04/2020 08:34,,1560-1564,,7,18,,Matern Child Health J,,,,,,,,eng,,,,,,,PMID: 25108501 PMCID: PMC4295498,,,,"Humans; Child; Systems Analysis; Public Health; Child Health Services/*organization & administration; Health Behavior; Quality Assurance, Health Care; Maternal-Child Health Centers/organization & administration; 00; Maternal Health Services/*organization & administration; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FBPDR3PA,journalArticle,2014,"Rwashana, Agnes Semwanga; Nakubulwa, Sarah; Nakakeeto-Kijjambu, Margaret; Adam, Taghreed",Advancing the application of systems thinking in health: understanding the dynamics of neonatal mortality in Uganda.,Health research policy and systems,,1478-4505 1478-4505,10.1186/1478-4505-12-36,,"BACKGROUND: Of the three million newborns that die each year, Uganda ranks fifth highest in neonatal mortality rates, with 43,000 neonatal deaths each year. Despite child survival and safe motherhood programmes towards reducing child mortality, insufficient attention has been given to this critical first month of life. There is urgent need to innovatively employ alternative solutions that take into account the intricate complexities of neonatal health and the health systems. In this paper, we set out to empirically contribute to understanding the causes of the stagnating neonatal mortality by applying a systems thinking approach to explore the dynamics arising from the neonatal health complexity and non-linearity and its interplay with health systems factors, using Uganda as a case study. METHODS: Literature reviews and interviews were conducted in two divisions of Kampala district with high neonatal mortality rates with mothers at antenatal clinics and at home, village health workers, community leaders, healthcare decision and policy makers, and frontline health workers from both public and private health facilities. Data analysis and brainstorming sessions were used to develop causal loop diagrams (CLDs) depicting the causes of neonatal mortality, which were validated by local and international stakeholders. RESULTS: We developed two CLDs for demand and supply side issues, depicting the range of factors associated with neonatal mortality such as maternal health, level of awareness of maternal and newborn health, and availability and quality of health services, among others. Further, the reinforcing and balancing feedback loops that resulted from this complexity were also examined. The potential high leverage points include special gender considerations to ensure that girls receive essential education, thereby increasing maternal literacy rates, improved socioeconomic status enabling mothers to keep healthy and utilise health services, improved supervision, and internal audits at the health facilities as well as addressing the gaps in resources (human, logistics, and drugs). CONCLUSIONS: Synthesis of theoretical concepts through CLDs facilitated our understanding and interpretation of the interactions and feedback loops that contributed to the stagnant neonatal mortality rates in Uganda, which is the first step towards discussing and exploring the potential strategies and their likely impact.",08/08/2014,26/11/2018 12:51,14/04/2020 08:35,,36,,,12,,Health Res Policy Syst,,,,,,,,eng,,,,,,,PMID: 25104047 PMCID: PMC4134459,,,,"Humans; Socioeconomic Factors; Adult; Female; Young Adult; Child; Adolescent; Pregnancy; *Delivery of Health Care; Infant; Infant, Newborn; Health Literacy; 00; *Infant Mortality; *Maternal Health Services; *Maternal Welfare; Health Resources; Uganda/epidemiology; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YW6V98RP,journalArticle,2014,"Manabe, Yukari C.; Campbell, James D.; Ovuga, Emilio; Maling, Samuel; Bollinger, Robert C.; Sewankambo, Nelson",Optimisation of the Medical Education Partnership Initiative to address African health-care challenges.,The Lancet. Global health,,2214-109X 2214-109X,10.1016/S2214-109X(14)70235-9,,,2014-07,26/11/2018 12:51,14/04/2020 08:34,,e392,,7,2,,Lancet Glob Health,,,,,,,,eng,,,,,,,PMID: 25103390 PMCID: PMC4537513,,,,"Humans; United States; *Cooperative Behavior; 00; Uganda; Education, Medical/*methods; Delivery of Health Care/*methods; *Schools, Medical; Africa South of the Sahara; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TUKELEE4,journalArticle,2014,"Agyepong, Irene A.; Aryeetey, Geneieve C.; Nonvignon, Justice; Asenso-Boadi, Francis; Dzikunu, Helen; Antwi, Edward; Ankrah, Daniel; Adjei-Acquah, Charles; Esena, Reuben; Aikins, Moses; Arhinful, Daniel K.",Advancing the application of systems thinking in health: provider payment and service supply behaviour and incentives in the Ghana National Health Insurance Scheme--a systems approach.,Health research policy and systems,,1478-4505 1478-4505,10.1186/1478-4505-12-35,,"BACKGROUND: Assuring equitable universal access to essential health services without exposure to undue financial hardship requires adequate resource mobilization, efficient use of resources, and attention to quality and responsiveness of services. The way providers are paid is a critical part of this process because it can create incentives and patterns of behaviour related to supply. The objective of this work was to describe provider behaviour related to supply of health services to insured clients in Ghana and the influence of provider payment methods on incentives and behaviour. METHODS: A mixed methods study involving grey and published literature reviews, as well as health management information system and primary data collection and analysis was used. Primary data collection involved in-depth interviews, observations of time spent obtaining service, prescription analysis, and exit interviews with clients. Qualitative data was analysed manually to draw out themes, commonalities, and contrasts. Quantitative data was analysed in Excel and Stata. Causal loop and cause tree diagrams were used to develop a qualitative explanatory model of provider supply incentives and behaviour related to payment method in context. RESULTS: There are multiple provider payment methods in the Ghanaian health system. National Health Insurance provider payment methods are the most recent additions. At the time of the study, the methods used nationwide were the Ghana Diagnostic Related Groupings payment for services and an itemized and standardized fee schedule for medicines. The influence of provider payment method on supply behaviour was sometimes intuitive and sometimes counter intuitive. It appeared to be related to context and the interaction of the methods with context and each other rather than linearly to any given method. CONCLUSIONS: As countries work towards Universal Health Coverage, there is a need to holistically design, implement, and manage provider payment methods reforms from systems rather than linear perspectives, since the latter fail to recognize the effects of context and the between-methods and context interactions in producing net effects.",05/08/2014,26/11/2018 12:51,14/04/2020 08:34,,35,,,12,,Health Res Policy Syst,,,,,,,,eng,,,,,,,PMID: 25096303 PMCID: PMC4142471,,,,Humans; Delivery of Health Care/*economics; Ghana; *Motivation; 00; National Health Programs/*economics; Health Personnel/*economics; *Income; Health Services Accessibility/economics; Salaries and Fringe Benefits; Universal Coverage/economics; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GXAETZQ7,journalArticle,2015,"van Karnebeek, Clara D. M.; Mohammadi, Tima; Tsao, Nicole; Sinclair, Graham; Sirrs, Sandra; Stockler, Sylvia; Marra, Carlo",Health economic evaluation of plasma oxysterol screening in the diagnosis of Niemann-Pick Type C disease among intellectually disabled using discrete event simulation.,Molecular genetics and metabolism,,1096-7206 1096-7192,10.1016/j.ymgme.2014.07.004,,"BACKGROUND: Recently a less invasive method of screening and diagnosing Niemann-Pick C (NP-C) disease has emerged. This approach involves the use of a metabolic screening test (oxysterol assay) instead of the current practice of clinical assessment of patients suspected of NP-C (review of medical history, family history and clinical examination for the signs and symptoms). Our objective is to compare costs and outcomes of plasma oxysterol screening versus current practice in diagnosis of NP-C disease among intellectually disabled (ID) patients using decision-analytic methods. METHODS: A discrete event simulation model was conducted to follow ID patients through the diagnosis and treatment of",2015-02,26/11/2018 12:51,14/04/2020 08:35,,226-232,,2,114,,Mol Genet Metab,,,,,,,,eng,Copyright (c) 2014 Elsevier Inc. All rights reserved.,,,,,,PMID: 25095726,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Female; Male; Child; Decision Support Techniques; Quality of Life; Adolescent; Computer Simulation; Child, Preschool; Diagnosis; Filipin staining; Global developmental delay; Inborn error of metabolism; Intellectual disability; Niemann-Pick Disease, Type C/*diagnosis; NPC1; NPC2; Oxysterol; Screening; Sterols/*blood; Treatment; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, SWPAKZBK,journalArticle,2014,"Haji, Faizal A.; Da Silva, Celina; Daigle, Delton T.; Dubrowski, Adam",From bricks to buildings: adapting the Medical Research Council framework to develop programs of research in simulation education and training for the health professions.,Simulation in healthcare : journal of the Society for Simulation in Healthcare,,1559-713X 1559-2332,10.1097/SIH.0000000000000039,,"SUMMARY STATEMENT: Presently, health care simulation research is largely conducted on a study-by-study basis. Although such ""project-based"" research generates a plethora of evidence, it can be chaotic and contradictory. A move toward sustained, thematic, theory-based programs of research is necessary to advance knowledge in the field. Recognizing that simulation is a complex intervention, we present a framework for developing research programs in simulation-based education adapted from the Medical Research Council (MRC) guidance. This framework calls for an iterative approach to developing, refining, evaluating, and implementing simulation interventions. The adapted framework guidance emphasizes: (1) identification of theory and existing evidence; (2) modeling and piloting interventions to clarify active ingredients and identify mechanisms linking the context, intervention, and outcomes; and (3) evaluation of intervention processes and outcomes in both the laboratory and real-world setting. The proposed framework will aid simulation researchers in developing more robust interventions that optimize simulation-based education and advance our understanding of simulation pedagogy.",2014-08,26/11/2018 12:51,14/04/2020 08:34,,249-259,,4,9,,Simul Healthc,,,,,,,,eng,,,,,,,PMID: 25090169,,,,Humans; Program Development; Guidelines as Topic; Computer Simulation/*trends; 00; Health Occupations/*education; Health Services Research/*trends; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KE86NN2C,journalArticle,2014,"de Andrade, Luciano; Lynch, Catherine; Carvalho, Elias; Rodrigues, Clarissa Garcia; Vissoci, Joao Ricardo Nickenig; Passos, Guttenberg Ferreira; Pietrobon, Ricardo; Nihei, Oscar Kenji; de Barros Carvalho, Maria Dalva",System dynamics modeling in the evaluation of delays of care in ST-segment elevation myocardial infarction patients within a tiered health system.,PloS one,,1932-6203 1932-6203,10.1371/journal.pone.0103577,,"BACKGROUND: Mortality rates amongst ST segment elevation myocardial infarction (STEMI) patients remain high, especially in developing countries. The aim of this study was to evaluate the factors related with delays in the treatment of STEMI patients to support a strategic plan toward structural and personnel modifications in a primary hospital aligning its process with international guidelines. METHODS AND FINDINGS: The study was conducted in a primary hospital localized in Foz do Iguacu, Brazil. We utilized a qualitative and quantitative integrated analysis including on-site observations, interviews, medical records analysis, Qualitative Comparative Analysis (QCA) and System Dynamics Modeling (SD). Main cause of delays were categorized into three themes: a) professional, b) equipment and c) transportation logistics. QCA analysis confirmed four main stages of delay to STEMI patient's care in relation to the 'Door-in-Door-out' time at the primary hospital. These stages and their average delays in minutes were: a) First Medical Contact (From Door-In to the first contact with the nurse and/or physician): 7 minutes; b) Electrocardiogram acquisition and review by a physician: 28 minutes; c) ECG transmission and Percutaneous Coronary Intervention Center team feedback time: 76 minutes; and d) Patient's Transfer Waiting Time: 78 minutes. SD baseline model confirmed the system's behavior with all occurring delays and the need of improvements. Moreover, after model validation and sensitivity analysis, results suggested that an overall improvement of 40% to 50% in each of these identified stages would reduce the delay. CONCLUSIONS: This evaluation suggests that investment in health personnel training, diminution of bureaucracy, and management of guidelines might lead to important improvements decreasing the delay of STEMI patients' care. In addition, this work provides evidence that SD modeling may highlight areas where health system managers can implement and evaluate the necessary changes in order to improve the process of care.",2014,26/11/2018 12:51,14/04/2020 08:34,,e103577,,7,9,,PLoS One,,,,,,,,eng,,,,,,,PMID: 25079362 PMCID: PMC4117497,,,,"Delivery of Health Care/*organization & administration; Humans; *Models, Organizational; Brazil; Time and Motion Studies; 00; Electrocardiography; Myocardial Infarction/physiopathology/*therapy; Review",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PIBD65P3,journalArticle,2014,"Chami, Goylette F.; Ahnert, Sebastian E.; Voors, Maarten J.; Kontoleon, Andreas A.",Social network analysis predicts health behaviours and self-reported health in African villages.,PloS one,,1932-6203 1932-6203,10.1371/journal.pone.0103500,,"The provision of healthcare in rural African communities is a highly complex and largely unsolved problem. Two main difficulties are the identification of individuals that are most likely affected by disease and the prediction of responses to health interventions. Social networks have been shown to capture health outcomes in a variety of contexts. Yet, it is an open question as to what extent social network analysis can identify and distinguish among households that are most likely to report poor health and those most likely to respond to positive behavioural influences. We use data from seven highly remote, post-conflict villages in Liberia and compare two prominent network measures: in-degree and betweenness. We define in-degree as the frequency in which members from one household are named by another household as a friends. Betweenness is defined as the proportion of shortest friendship paths between any two households in a network that traverses a particular household. We find that in-degree explains the number of ill family members, whereas betweenness explains engagement in preventative health. In-degree and betweenness independently explained self-reported health and behaviour, respectively. Further, we find that betweenness predicts susceptibility to, instead of influence over, good health behaviours. The results suggest that targeting households based on network measures rather than health status may be effective for promoting the uptake of health interventions in rural poor villages.",2014,26/11/2018 12:51,14/04/2020 08:34,,e103500,,7,9,,PLoS One,,,,,,,,eng,,,,,,,PMID: 25072820 PMCID: PMC4114748,,,,Humans; Socioeconomic Factors; Health Status; *Social Support; *Health Behavior; Rural Population; Health Services; 00; Liberia; Self Report; Friends; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, T8V3TGIE,journalArticle,2014,"Dai, C.; Cai, X. H.; Cai, Y. P.; Guo, H. C.; Sun, W.; Tan, Q.; Huang, G. H.",An integrated simulation and optimization approach for managing human health risks of atmospheric pollutants by coal-fired power plants.,Journal of the Air & Waste Management Association (1995),,1096-2247 1096-2247,,,"UNLABELLED: This research developed a simulation-aided nonlinear programming model (SNPM). This model incorporated the consideration of pollutant dispersion modeling, and the management of coal blending and the related human health risks within a general modeling framework In SNPM, the simulation effort (i.e., California puff [CALPUFF]) was used to forecast the fate of air pollutants for quantifying the health risk under various conditions, while the optimization studies were to identify the optimal coal blending strategies from a number of alternatives. To solve the model, a surrogate-based indirect search approach was proposed, where the support vector regression (SVR) was used to create a set of easy-to-use and rapid-response surrogates for identifying the function relationships between coal-blending operating conditions and health risks. Through replacing the CALPUFF and the corresponding hazard quotient equation with the surrogates, the computation efficiency could be improved. The developed SNPM was applied to minimize the human health risk associated with air pollutants discharged from Gaojing and Shijingshan power plants in the west of Beijing. Solution results indicated that it could be used for reducing the health risk of the public in the vicinity of the two power plants, identifying desired coal blending strategies for decision makers, and considering a proper balance between coal purchase cost and human health risk. IMPLICATIONS: A simulation-aided nonlinear programming model (SNPM) is developed. It integrates the advantages of CALPUFF and nonlinear programming model. To solve the model, a surrogate-based indirect search approach based on the combination of support vector regression and genetic algorithm is proposed. SNPM is applied to reduce the health risk caused by air pollutants discharged from Gaojing and Shijingshan power plants in the west of Beijing. Solution results indicate that it is useful for generating coal blending schemes, reducing the health risk of the public, reflecting the trade-offbetween coal purchase cost and health risk.",2014-06,26/11/2018 12:51,14/04/2020 08:34,,704-720,,6,64,,J Air Waste Manag Assoc,,,,,,,,eng,,,,,,,PMID: 25039204,,,,Humans; Risk Factors; *Computer Simulation; China; *Health Status Indicators; 00; Environmental Monitoring; *Coal; *Nonlinear Dynamics; *Power Plants; Air Pollutants/adverse effects/*analysis; Respiration Disorders/etiology; Smoke/*analysis; Software Design; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, W4I7SJY6,journalArticle,2015,"Foster, Adriana; Chaudhary, Neelam; Murphy, James; Lok, Benjamin; Waller, Jennifer; Buckley, Peter F.","The Use of Simulation to Teach Suicide Risk Assessment to Health Profession Trainees-Rationale, Methodology, and a Proof of Concept Demonstration with a Virtual Patient.",Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry,,1545-7230 1042-9670,10.1007/s40596-014-0185-9,,"OBJECTIVE: There is increasing use of educational technologies in medical and surgical specialties. Described herein is the development and application of an interactive virtual patient (VP) to teach suicide risk assessment to health profession trainees. We studied the effect of the following: (1) an interaction with a bipolar VP who attempts suicide or (2) completion of a video-teaching module on interviewing a bipolar patient, on medical students' proficiency in assessing suicide risk in standardized patients. We hypothesized that students who interact with a bipolar VP will be at least as likely to assess suicide risk, as their peers who completed a video module. METHODS: In a randomized, controlled study, we compared the frequency with which second-year students at the Medical College of Georgia asked suicide risk and bipolar symptoms questions by VP/video group. RESULTS: We recruited 67 students. The VP group inquired more frequently than the video group in 4 of 5 suicide risk areas and 11 of 14 other bipolar symptomatology areas. There were minimal to small effect sizes in favor of the VP technology. The students preferred the video over the VP as an educational tool (p = 0.007). CONCLUSIONS: Our study provides proof of concept that both VP and video module approaches are feasible for teaching students to assess suicide risk, and we present evidence about the role of active learning to improve communication skills. Depending on the learning context, interviewing a VP or observation of a videotaped interview can enhance the students' suicide risk assessment proficiency in an interview with a standardized patient. An interactive VP is a plausible modality to deliver basic concepts of suicide risk assessment to medical students, can facilitate individual preferences by providing easy access and portability, and has potential generalizability to other aspects of psychiatric training.",2015-12,26/11/2018 12:51,14/04/2020 08:34,,620-629,,6,39,,Acad Psychiatry,,,,,,,,eng,,,,,,,PMID: 25026950,,,,"Humans; Adult; Female; Male; Young Adult; Risk Assessment/methods; Problem-Based Learning/*methods; *User-Computer Interface; Computer-Assisted Instruction/*methods; 00; Suicide risk; Education, Medical/*methods; Video; *Suicide; Bipolar Disorder/diagnosis; Communication Checklist; Educational Technology/*standards; Interview, Psychological/methods; Simulation Training/*standards; Virtual patient; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UIJT8J59,journalArticle,2014,"Bickel, W. K.; Moody, L.; Quisenberry, A. J.; Ramey, C. T.; Sheffer, C. E.",A Competing Neurobehavioral Decision Systems model of SES-related health and behavioral disparities.,Preventive medicine,,1096-0260 0091-7435,10.1016/j.ypmed.2014.06.032,,"We propose that executive dysfunction is an important component relating to the socio-economic status gradient of select health behaviors. We review and find evidence supporting an SES gradient associated with (1) negative health behaviors (e.g., obesity, excessive use of alcohol, tobacco and other substances), and (2) executive dysfunction. Moreover, the evidence supports that stress and insufficient cognitive resources contribute to executive dysfunction and that executive dysfunction is evident among individuals who smoke cigarettes, are obese, abuse alcohol, and use illicit drugs. Collectively these data support the dual system model of cognitive control, referred to here as the Competing Neurobehavioral Decision Systems hypothesis. The implications of these relationships for intervention and social justice considerations are discussed.",2014-11,26/11/2018 12:51,14/04/2020 08:34,,37-43,,,68,,Prev Med,,,,,,,,eng,Copyright (c) 2014 Elsevier Inc. All rights reserved.,,,,,,PMID: 25008219 PMCID: PMC4253853,,,,"Humans; Socioeconomic Factors; United States; Behavior; *Health Behavior; *Health Status Disparities; *Cognition; *Decision Making; Smoking/psychology; 1; Social Behavior; Health disparities; *Social Class; Competing Neurobehavioral Decision Systems; Executive function decision system; Impulsive decision system; Obesity/psychology; SES gradient; Stress, Psychological; Substance-Related Disorders/psychology; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, K469LKE7,journalArticle,2014,"Chinchilli, Vernon M.; Wang, Li",Value of simulation studies to assess health policies.,The Journal of allergy and clinical immunology,,1097-6825 0091-6749,10.1016/j.jaci.2014.05.027,,,2014-10,26/11/2018 12:51,14/04/2020 08:34,,916,,4,134,,J Allergy Clin Immunol,,,,,,,,eng,,,,,,,PMID: 24985404,,,,Humans; *Medication Adherence; 00; adherence; Anti-Asthmatic Agents/*therapeutic use; Asthma/*drug therapy; controller medication; Monte Carlo simulation study; probability distribution; sensitivity analysis; Uncontrolled asthma; 100; ****more for intro,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, H3G6BXJV,journalArticle,2014,"Beer, Jenay M.; McBride, Sara E.; Mitzner, Tracy L.; Rogers, Wendy A.",Understanding challenges in the front lines of home health care: a human-systems approach.,Applied ergonomics,,1872-9126 0003-6870,10.1016/j.apergo.2014.05.019,,"A human-systems perspective is a fruitful approach to understanding home health care because it emphasizes major individual components of the system - persons, equipment/technology, tasks, and environments - as well as the interaction between these components. The goal of this research was to apply a human-system perspective to consider the capabilities and limitations of the persons, in relation to the demands of the tasks and equipment/technology in home health care. Identification of challenges and mismatches between the person(s) capabilities and the demands of providing care provide guidance for human factors interventions. A qualitative study was conducted with 8 home health Certified Nursing Assistants and 8 home health Registered Nurses interviewed about challenges they encounter in their jobs. A systematic categorization of the challenges the care providers reported was conducted and human factors recommendations were proposed in response, to improve home health. The challenges inform a human-systems model of home health care.",2014-11,26/11/2018 12:51,14/04/2020 08:34,,1687-1699,,6,45,,Appl Ergon,,,,,,,,eng,Copyright (c) 2014 Elsevier Ltd and The Ergonomics Society. All rights reserved.,,,,,,PMID: 24958610 PMCID: PMC4180111,,,,"Humans; Patient Safety; Qualitative Research; *Ergonomics; Healthcare; Quality Assurance, Health Care; Needs Assessment; 00; Human factors; Equipment and Supplies; Home Care Services/*manpower; Human-systems; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KWUFCVET,journalArticle,2014,"Bolesta, Scott; Chmil, Joyce V.",Interprofessional education among student health professionals using human patient simulation.,American journal of pharmaceutical education,,1553-6467 0002-9459,10.5688/ajpe78594,,"OBJECTIVE: To describe the planning, implementation, and outcomes of an interprofessional education clinical laboratory facilitated through human patient simulation. DESIGN: An interprofessional education clinical laboratory was developed with a patient-care scenario of acute exacerbation of heart failure that incorporated the use of a high-fidelity patient simulator. Pharmacy and nursing students assumed clinical roles in this realistic scenario and collaborated to diagnose and treat the patient. ASSESSMENT: Student attitudes toward and readiness to participate in interprofessional education improved following participation in the laboratory. Students reported that the greatest benefit of the experience was in their communication skills. CONCLUSION: Students' ability to participate in interprofessional education experiences and their attitudes toward them improved following participation in this curricular initiative. Further evaluation of the impact of interprofessional education on student learning outcomes and changes in practice is warranted.",17/06/2014,26/11/2018 12:51,14/04/2020 08:34,,94,,5,78,,Am J Pharm Educ,,,,,,,,eng,,,,,,,PMID: 24954934 PMCID: PMC4064494,,,,"Humans; Clinical Competence; Curriculum; Students, Nursing/*psychology; Interprofessional Relations; Communication; Education, Nursing/*methods; Cooperative Behavior; simulation; Patient Simulation; 00; interprofessional education; Education, Pharmacy/*methods; Heart Failure/therapy; nursing students; pharmacy students; Students, Pharmacy/*psychology; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GJLDAB2S,journalArticle,2014,"Gilson, Lucy; Elloker, Soraya; Olckers, Patti; Lehmann, Uta",Advancing the application of systems thinking in health: South African examples of a leadership of sensemaking for primary health care.,Health research policy and systems,,1478-4505 1478-4505,10.1186/1478-4505-12-30,,"BACKGROUND: New forms of leadership are required to bring about the fundamental health system changes demanded by primary health care (PHC). Using theory about complex adaptive systems and policy implementation, this paper considers how actors' sensemaking and the exercise of discretionary power currently combine to challenge PHC re-orientation in the South African health system; and provides examples of leadership practices that promote sensemaking and power use in support of PHC. METHODS: The paper draws on observational, interview, and reflective data collected as part of the District Innovation and Action Learning for Health Systems Development (DIALHS) project being implemented in Cape Town, South Africa. Undertaken collaboratively between health managers and researchers, the project is implemented through cycles of action-learning, including systematic reflection and synthesis. It includes a particular focus on how local health managers can better support front line facility managers in strengthening PHC. RESULTS: The results illuminate how the collective understandings of staff working at the primary level - of their working environment and changes within it - act as a barrier to centrally-led initiatives to strengthen PHC. Staff often fail to take ownership of such initiatives and experience them as disempowering. Local area managers, located between the centre and the service frontline, have a vital role to play in providing a leadership of sensemaking to mediate these challenges. Founded on personal values, such leadership entails, for example, efforts to nurture PHC-aligned values and mind-sets among staff; build relationships and support the development of shared meanings about change; instil a culture of collective inquiry and mutual accountability; and role-model management practices, including using language to signal meaning. CONCLUSIONS: PHC will only become a lived reality within the South African health system when frontline staff are able to make sense of policy intentions and incorporate them into their everyday routines and practices. This requires a leadership of sensemaking that enables front line staff to exercise their collective discretionary power in strengthening PHC. We hope this theoretically-framed analysis of one set of experiences stimulates wider thinking about the leadership needed to sustain primary health care in other settings.",16/06/2014,26/11/2018 12:51,14/04/2020 08:34,,30,,,12,,Health Res Policy Syst,,,,,,,,eng,,,,,,,PMID: 24935658 PMCID: PMC4066696,,,,Humans; Quality Improvement; Delivery of Health Care/organization & administration/standards; *Leadership; Attitude of Health Personnel; Systems Theory; 00; South Africa; Comprehension; Health Care Reform/organization & administration; Practice Management/organization & administration; Primary Health Care/*organization & administration/standards; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, S7SYCDYD,journalArticle,2014,"Kwamie, Aku; van Dijk, Han; Agyepong, Irene Akua",Advancing the application of systems thinking in health: realist evaluation of the Leadership Development Programme for district manager decision-making in Ghana.,Health research policy and systems,,1478-4505 1478-4505,10.1186/1478-4505-12-29,,"BACKGROUND: Although there is widespread agreement that strong district manager decision-making improves health systems, understanding about how the design and implementation of capacity-strengthening interventions work is limited. The Ghana Health Service has adopted the Leadership Development Programme (LDP) as one intervention to support the development of management and leadership within district teams. This paper seeks to address how and why the LDP 'works' when it is introduced into a district health system in Ghana, and whether or not it supports systems thinking in district teams. METHODS: We undertook a realist evaluation to investigate the outcomes, contexts, and mechanisms of the intervention. Building on two working hypotheses developed from our earlier work, we developed an explanatory case study of one rural district in the Greater Accra Region of Ghana. Data collection included participant observation, document review, and semi-structured interviews with district managers prior to, during, and after the intervention. Working backwards from an in-depth analysis of the context and observed short- and medium-term outcomes, we drew a causal loop diagram to explain interactions between contexts, outcomes, and mechanisms. RESULTS: The LDP was a valuable experience for district managers and teams were able to attain short-term outcomes because the novel approach supported teamwork, initiative-building, and improved prioritisation. However, the LDP was not institutionalised in district teams and did not lead to increased systems thinking. This was related to the context of high uncertainty within the district, and hierarchical authority of the system, which triggered the LDP's underlying goal of organisational control. CONCLUSIONS: Consideration of organisational context is important when trying to sustain complex interventions, as it seems to influence the gap between short- and medium-term outcomes. More explicit focus on systems thinking principles that enable district managers to better cope with their contexts may strengthen the institutionalisation of the LDP in the future.",16/06/2014,26/11/2018 12:51,14/04/2020 08:34,,29,,,12,,Health Res Policy Syst,,,,,,,,eng,,,,,,,PMID: 24935521 PMCID: PMC4073809,,,,Humans; Program Development; Quality Improvement; *Leadership; Attitude of Health Personnel; Systems Theory; Ghana; *Decision Making; Perception; 00; Patient Care Team/organization & administration/standards; Administrative Personnel/psychology; Practice Management/*organization & administration/standards; Regional Medical Programs/organization & administration/standards; Rural Health Services/*organization & administration/standards; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 68IJNEZP,journalArticle,2014,"Chao, Jianqian; Zong, Mengmeng; Xu, Hui; Yu, Qing; Jiang, Lili; Li, Yunyun; Song, Long; Liu, Pei",The long-term effect of community-based health management on the elderly with type 2 diabetes by the Markov modeling.,Archives of gerontology and geriatrics,,1872-6976 0167-4943,10.1016/j.archger.2014.05.006,,"The aim of this study was to assess the long-term effects of community-based health management on elderly diabetic patients using a Markov model. A Markov decision model was used to simulate the natural history of diabetes. Data were obtained from our randomized trials of elderly with type 2 diabetes and from the published literature. One hundred elderly patients with type 2 diabetes were randomly allocated to either the management or the control group in a one-to-one ratio. The management group participated in a health management program for 18 months in addition to receiving usual care. The control group only received usual care. Measurements were performed on both groups at baseline and after 18 months. The Markov model predicted that for every 1000 diabetic patients receiving health management, approximately 123 diabetic patients would avoid complications, and approximately 37 would avoid death over the next 13 years. The results suggest that the health management program had a positive long-term effect on the health of elderly diabetic patients. The Markov model appears to be useful in health care planning and decision-making aimed at reducing the financial and social burden of diabetes.",2014-10,26/11/2018 12:51,14/04/2020 08:34,,353-359,,2,59,,Arch Gerontol Geriatr,,,,,,,,eng,Copyright (c) 2014 Elsevier Ireland Ltd. All rights reserved.,,,,,,PMID: 24929252,,,,"Humans; Surveys and Questionnaires; Health Services Research; Outcome and Process Assessment (Health Care); Female; Male; Middle Aged; Aged; *Markov Chains; Aged, 80 and over; Decision Making; China; Community Health Services/*organization & administration; Markov model; Patient Care Planning; 1; Diabetes Mellitus, Type 2/*therapy; Elderly diabetic patients; Health management; Long-term effect; 210",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DW7LWTFT,journalArticle,2014,"Macal, Charles M.; North, Michael J.; Collier, Nicholson; Dukic, Vanja M.; Wegener, Duane T.; David, Michael Z.; Daum, Robert S.; Schumm, Philip; Evans, James A.; Wilder, Jocelyn R.; Miller, Loren G.; Eells, Samantha J.; Lauderdale, Diane S.",Modeling the transmission of community-associated methicillin-resistant Staphylococcus aureus: a dynamic agent-based simulation.,Journal of translational medicine,,1479-5876 1479-5876,10.1186/1479-5876-12-124,,"BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) has been a deadly pathogen in healthcare settings since the 1960s, but MRSA epidemiology changed since 1990 with new genetically distinct strain types circulating among previously healthy people outside healthcare settings. Community-associated (CA) MRSA strains primarily cause skin and soft tissue infections, but may also cause life-threatening invasive infections. First seen in Australia and the U.S., it is a growing problem around the world. The U.S. has had the most widespread CA-MRSA epidemic, with strain type USA300 causing the great majority of infections. Individuals with either asymptomatic colonization or infection may transmit",12/05/2014,26/11/2018 12:51,14/04/2020 08:34,,124,,,12,,J Transl Med,,,,,,,,eng,,,,,,,PMID: 24886400 PMCID: PMC4049803,,,,"Humans; *Models, Theoretical; Disease Outbreaks; 00; Methicillin-Resistant Staphylococcus aureus/*isolation & purification; Staphylococcal Infections/epidemiology/microbiology/*transmission; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RA93VRBB,journalArticle,2014,"Bagnasco, Annamaria; Pagnucci, Nicola; Tolotti, Angela; Rosa, Francesca; Torre, Giancarlo; Sasso, Loredana",The role of simulation in developing communication and gestural skills in medical students.,BMC medical education,,1472-6920 1472-6920,10.1186/1472-6920-14-106,,"BACKGROUND: International studies have shown that laboratory training, particularly through the application of the principles of simulation learning, is an effective means of developing the communication and gestural skills of healthcare professionals. At the Advanced Simulation Center of the University of Genoa we have therefore established the first clinical skill laboratory with medical school students and an interprofessional team of trainers, as the first step towards developing simulation training of both medical and nursing students at our University.The aim of this study was to assess student satisfaction with laboratory training in an Advanced Simulation Center. METHODS: All of the third-year students of the Medical School (n = 261) were invited to participate in the laboratory sessions at the Advanced Simulation Center. They were divided into groups and attended the Center for one week. The team of trainers included medical doctors and nurses involved in teaching at the University Medicine and Nursing programs. At the end of the week, the students were administered an anonymous questionnaire made up of two sections: the first one was on the content of individual laboratory sessions; the second on the training methods, materials used and the trainers. A five-point Likert scale was used to measure satisfaction. RESULTS: According to the students all of the topics covered by the laboratory sessions were irreplaceable. Questionnaire results showed a high level of satisfaction with the methods used, the instruments developed, and with the expertise and approachability of the educators. Almost all of the students wanted to participate in similar laboratory activities in the future. CONCLUSIONS: The study highlighted the need to permanently integrate laboratory training sessions into the curriculum of medical students, who found them very useful and stimulating. The limit of this study was that only the teaching staff was interprofessional, and the students were only 3rd Year students of medicine.In the future, we hope to include also nursing students because they will need to learn how to deal with aspects of their clinical practice that require an interprofessional approach.",23/05/2014,26/11/2018 12:51,14/04/2020 08:34,,106,,,14,,BMC Med Educ,,,,,,,,eng,,,,,,,PMID: 24885330 PMCID: PMC4039313,,,,"Humans; Surveys and Questionnaires; Female; Male; Young Adult; *Patient Simulation; Attitude of Health Personnel; 00; *Students, Medical; *Clinical Competence/standards; Education, Medical/methods; Gestures; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, USQD4B38,journalArticle,2014,"Zafari, Zafar; Lynd, Larry D.; FitzGerald, J. Mark; Sadatsafavi, Mohsen",Economic and health effect of full adherence to controller therapy in adults with uncontrolled asthma: a simulation study.,The Journal of allergy and clinical immunology,,1097-6825 0091-6749,10.1016/j.jaci.2014.04.009,,BACKGROUND: Adherence to evidence-based controller treatments for asthma is disappointingly low in many jurisdictions. Quantifying the burden associated with suboptimal adherence in patients with uncontrolled asthma will help establish the priorities for policymakers. OBJECTIVE: We sought to quantify the benefits in the United States of improving adherence to controller therapies in adults with uncontrolled asthma in terms of health care costs and quality-adjusted life years (QALYs). METHODS: A Markov model of asthma was created to simulate the effect of treatment with controller medications on asthma control and exacerbations over a,2014-10,26/11/2018 12:51,14/04/2020 08:34,,908-915.e3,,4,134,,J Allergy Clin Immunol,,,,,,,,eng,"Copyright (c) 2014 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.",,,,,,PMID: 24875619,,,,Humans; United States; Cost-Benefit Analysis; Evidence-Based Medicine; Quality-Adjusted Life Years; Health Care Costs; Adult; Markov Chains; Computer Simulation; Cost of Illness; Time Factors; *Medication Adherence; 1; adherence; Anti-Asthmatic Agents/economics/*therapeutic use; Asthma; Asthma/*drug therapy/economics; cost-effectiveness analysis; decision analysis; evidence-based treatment; Markov; 320,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, J4YAQQFX,journalArticle,2014,"Clark, Heather R.; Ramirez, Albert; Drake, Kelly N.; Beaudoin, Christopher E.; Garney, Whitney R.; Wendel, Monica L.; Outley, Corliss; Burdine, James N.; Player, Harold D.",Utilization of an interorganizational network analysis to evaluate the development of community capacity among a community-academic partnership.,"Progress in community health partnerships : research, education, and action",,1557-0541 1557-0541,10.1353/cpr.2014.0001,,"BACKGROUND: Following a community health assessment the Brazos Valley Health Partnership (BVHP) organized to address fragmentation of services and local health needs. This regional partnership employs the fundamental principles of community-based participatory research, fostering an equitable partnership with the aim of building community capacity to address local health issues. OBJECTIVES: This article describes changes in relationships as a result of capacity building efforts in a community-academic partnership. Growth in network structure among organizations is hypothesized to be indicative of less fragmentation of services for residents and increased capacity of the BVHP to collectively address local health issues. METHODS: Each of the participant organizations responded to a series of questions regarding its relationships with other organizations. Each organization was asked about information sharing, joint planning, resource sharing, and formal agreements with other organizations. The network survey has been administered 3 times between 2004 and 2009. RESULTS: Network density increased for sharing information and jointly planning events. Growth in the complexity of relationships was reported for sharing tangible resources and formal agreements. The average number of ties between organizations as well as the strength of relationships increased. CONCLUSION: This study provides evidence that the community capacity building efforts within these communities have contributed to beneficial changes in interorganizational relationships. Results from this analysis are useful for understanding how a community partnership's efforts to address access to care can strengthen a community's capacity for future action. Increased collaboration also leads to new assets, resources, and the transfer of knowledge and skills.",2014,26/11/2018 12:51,14/04/2020 08:34,,41-51,,1,8,,Prog Community Health Partnersh,,,,,,,,eng,,,,,,,PMID: 24859101,,,,Humans; Texas; Interinstitutional Relations; Community Networks/*organization & administration; 00; Information Dissemination/methods; Capacity Building/*methods; Program Development/methods; Program Evaluation/methods; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JMGFW3YV,journalArticle,2014,"Loving, Vilert A.; Edwards, David B.; Roche, Kevin T.; Steele, Joseph R.; Sapareto, Stephen A.; Byrum, Stephanie C.; Schomer, Donald F.",Monte Carlo simulation to analyze the cost-benefit of radioactive seed localization versus wire localization for breast-conserving surgery in fee-for-service health care systems compared with accountable care organizations.,AJR. American journal of roentgenology,,1546-3141 0361-803X,10.2214/AJR.13.11368,,"OBJECTIVE: In breast-conserving surgery for nonpalpable breast cancers, surgical reexcision rates are lower with radioactive seed localization (RSL) than wire localization. We evaluated the cost-benefit of switching from wire localization to RSL in two competing payment systems: a fee-for-service (FFS) system and a bundled payment system, which is typical for accountable care organizations. MATERIALS AND METHODS: A Monte Carlo simulation was developed to compare the cost-benefit of RSL and wire localization. Equipment utilization, procedural workflows, and regulatory overhead differentiate the cost between RSL and wire localization. To define a distribution of possible cost scenarios, the simulation randomly varied cost drivers within fixed ranges determined by hospital data, published literature, and expert input. Each scenario was replicated 1000 times using the pseudorandom number generator within Microsoft Excel, and results were analyzed for convergence. RESULTS: In a bundled payment system, RSL reduced total health care cost per patient relative to wire localization by an average of $115, translating into increased facility margin. In an FFS system, RSL reduced total health care cost per patient relative to wire localization by an average of $595 but resulted in decreased facility margin because of fewer surgeries. CONCLUSION: In a bundled payment system, RSL results in a modest reduction of cost per patient over wire localization and slightly increased margin. A fee-for-service system suffers moderate loss of revenue per patient with RSL, largely due to lower reexcision rates. The fee-for-service system creates a significant financial disincentive for providers to use RSL, although it improves clinical outcomes and reduces total health care costs.",2014-06,26/11/2018 12:52,14/04/2020 08:34,,1383-1388,,6,202,,AJR Am J Roentgenol,,,,,,,,eng,,,,,,,PMID: 24848839,,,,"Humans; United States; Cost-Benefit Analysis; Health Care Costs; Female; Middle Aged; Aged; Monte Carlo Method; Computer Simulation; Models, Statistical; Models, Economic; Prevalence; 00; Accountable Care Organizations/*economics/utilization; Brachytherapy/*economics/utilization; Breast Neoplasms/*economics/epidemiology/*therapy; Fee-for-Service Plans/*economics/statistics & numerical data; Mastectomy, Segmental/*economics/instrumentation/utilization; Reoperation/economics/utilization; Surgery, Computer-Assisted/*economics/utilization; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 59E6P6V9,journalArticle,2014,"Morton, Alec",Aversion to health inequalities in healthcare prioritisation: a multicriteria optimisation perspective.,Journal of health economics,,1879-1646 0167-6296,10.1016/j.jhealeco.2014.04.005,,"In this paper we discuss the prioritisation of healthcare projects where there is a concern about health inequalities, but the decision maker is reluctant to make explicit quantitative value judgements and the data systems only allow the measurement of health at an aggregate level. Our analysis begins with a standard welfare economic model of healthcare resource allocation. We show how - under the assumption that the healthcare projects under consideration have a small impact on individual health--the problem can be reformulated as one of finding a particular subset of the class of efficient solutions to an implied multicriteria optimisation problem. Algorithms for finding such solutions are readily available, and we demonstrate our approach through a worked example of treatment for clinical depression.",2014-07,26/11/2018 12:52,14/04/2020 08:35,,164-173,,,36,,J Health Econ,,,,,,,,eng,Copyright (c) 2014 Elsevier B.V. All rights reserved.,,,,,,PMID: 24831800,,,,"Humans; *Decision Support Techniques; Models, Economic; *Health Status Disparities; 00; Depressive Disorder/*economics/therapy; Health inequalities; Health Priorities/*economics/standards; Healthcare prioritisation; Healthcare resource allocation; Mathematical programming; Multicriteria decision analysis (MCDA); Resource Allocation/*economics/standards; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CSZP4FV8,journalArticle,2014,"Hartwell, D. A.; Grayling, M.; Kennedy, R. R.",Low-cost high-fidelity anaesthetic simulation.,Anaesthesia and intensive care,,0310-057X 0310-057X,,,"Simulation has been advocated as a useful training tool, and specific manikin simulators have been developed for use in this role. Debriefing and repetition have been identified as key to achieving educational goals and, while the technical features of manikin simulators can influence simulation outcomes, their cost and infrastructure requirements reduce their suitability for smaller healthcare facilities. We describe a local solution using biomedical calibration machines and modified basic manikins already available in our institution to form a high-fidelity anaesthetic simulator at minimal cost. This was effective in running high-fidelity, team-based in situ simulations and 'can't intubate, can't oxygenate' assessments for anaesthetic trainees. Though equipment in other centres may differ both in availability or suitability for simulation, the option we describe or similar may offer a low-cost solution for peripheral centres to run limited high-fidelity scenarios on a regular basis.",2014-05,26/11/2018 12:52,14/04/2020 08:34,,371-377,,3,42,,Anaesth Intensive Care,,,,,,,,eng,,,,,,,PMID: 24794478,,,,Humans; *Patient Simulation; Manikins; Anesthesiology/*education; 00; anaesthesia; simulation devices; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4STNCYGH,journalArticle,2016,"Cassettari, Lucia; Mosca, Marco; Mosca, Roberto; Rolando, Fabio; Costa, Mauro; Pisaturo, Valerio",IVF cycle cost estimation using Activity Based Costing and Monte Carlo simulation.,Health care management science,,1386-9620 1386-9620,10.1007/s10729-014-9282-2,,"The Authors present a new methodological approach in stochastic regime to determine the actual costs of an healthcare process. The paper specifically shows the application of the methodology for the determination of the cost of an Assisted reproductive technology (ART) treatment in Italy. The reason of this research comes from the fact that deterministic regime is inadequate to implement an accurate estimate of the cost of this particular treatment. In fact the durations of the different activities involved are unfixed and described by means of frequency distributions. Hence the need to determine in addition to the mean value of the cost, the interval within which it is intended to vary with a known confidence level. Consequently the cost obtained for each type of cycle investigated (in vitro fertilization and embryo transfer with or without intracytoplasmic sperm injection), shows tolerance intervals around the mean value sufficiently restricted as to make the data obtained statistically robust and therefore usable also as reference for any benchmark with other Countries. It should be noted that under a methodological point of view the approach was rigorous. In fact it was used both the technique of Activity Based Costing for determining the cost of individual activities of the process both the Monte Carlo simulation, with control of experimental error, for the construction of the tolerance intervals on the final result.",2016-03,26/11/2018 12:52,14/04/2020 08:34,,20-30,,1,19,,Health Care Manag Sci,,,,,,,,eng,,,,,,,PMID: 24752546,,,,"Humans; Fertilization in Vitro/*economics/methods; *Monte Carlo Method; Italy; Stochastic Processes; 00; Monte Carlo simulation; Activity Based Costing; Cost analysis; Costs and Cost Analysis/*methods; Embryo Transfer/*economics/methods; ICSI; IVF; Sperm Injections, Intracytoplasmic/economics/methods; Stochastic modeling; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VIJXGTKM,journalArticle,2014,"Chambers, David W.",Computer simulation of dental professionals as a moral community.,"Medicine, health care, and philosophy",,1572-8633 1386-7423,10.1007/s11019-014-9556-y,,"Current empirical studies of moral behavior of healthcare professionals are almost entirely focused on self-reports, usually collected under the assumption that an ethical disposition characterizes individuals across various contexts. It is well known, however, that individuals adjust their behavior to what they see being done by those in their peer group. That presents a methodological challenge to traditional research within a community of peers because the behavior of each individual is both the result of norms and a contributor to the norms of others. Computer simulations can be used to address this methodological challenge. A Markov replicator model that runs on an Excel spreadsheet was used to investigate a community with four agent types in the dental community: devious practitioners, ethical practitioners who avoid involvement in the poor ethics of others, ethical practitioners who accept it as part of their professional responsibility to challenge colleagues who act unprofessionally, and those who enforce ethical standards. A panel of leaders in the profession independently estimated parameters for the model and criteria for a possible distribution of agent types in the community. The simulation converged on distributions of the agent types that were very similar to the expectations of the panel. The simulation suggests the following characteristics of such moral communities: The structure of such communities is robust across a wide distribution. It appears that reduction in unethical behavior is more sensitive to the way ethical practitioners interact with each other than to sanctions the enforcement community imposes on unethical practitioners, and that large external interventions will be short lived.",2014-08,26/11/2018 12:52,14/04/2020 08:34,,467-476,,3,17,,Med Health Care Philos,,,,,,,,eng,,,,,,,PMID: 24737536,,,,"Humans; Markov Chains; *Computer Simulation; 00; *Morals; Dental Care/ethics; Dentists/*ethics; Ethics, Dental; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JKBALVM2,journalArticle,2014,"Nitschmann, Caroline; Bartz, Deborah; Johnson, Natasha R.",Gynecologic simulation training increases medical student confidence and interest in women's health.,Teaching and learning in medicine,,1532-8015 1040-1334,10.1080/10401334.2014.883984,,"BACKGROUND: Exposure to commonly performed gynecologic procedures via simulation has potential to improve medical student knowledge and foster confidence with procedures. PURPOSES: To implement and evaluate a gynecologic simulation curriculum for 3rd-year medical students during their obstetrics and gynecology core clerkship. METHODS: A gynecologic simulation curriculum was implemented for medical students during their obstetrics and gynecology clerkship. Participants completed pre-and postsurveys to assess learner confidence; effect on interest in a surgical field, women's health, and obstetrics and gynecology as a career; and whether the session met their learning needs. RESULTS: Fifty-nine students participated. Improved confidence in performing the procedures was noted when comparing mean survey scores before and after the simulation for IUD insertion and removal (1.9 pre, 4.3 post, p < .0001), for dilatation and curettage (1.7 pre, 3.8 post, p < .0001), and basic laparoscopy skills (2.1 pre, 4.3 post, p < .0001). An increase in pursuing a surgical field (3.3 pre, 3.6 post, p < .003) and interest in women's health (3.7 pre, 4.9 post, p < .004) was noted among students after the simulation session. The curriculum strongly met the students learning needs with a mean score of 4.54 on the 5-point scale. CONCLUSIONS: Gynecologic simulation training for medical students can increase confidence in procedures, interest in pursuing a surgical field and women's health, and was highly effective in meeting student learning needs.",2014,26/11/2018 12:52,14/04/2020 08:35,,160-163,,2,26,,Teach Learn Med,,,,,,,,eng,,,,,,,PMID: 24702552,,,,"Humans; Female; *Patient Simulation; *Self Efficacy; Boston; Manikins; 00; Education, Medical, Undergraduate; Students, Medical/*psychology; Gynecology/*education; *Women's Health; *Career Choice; Clinical Clerkship; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GW6CGIW8,journalArticle,2014,"Kostic, Marina; Jovanovic, Snezana; Tomovic, Marina; Milenkovic, Marija Popovic; Jankovic, Slobodan M.","Cost-effectiveness analysis of tocilizumab in combination with methotrexate for rheumatoid arthritis: a Markov model based on data from Serbia, country in socioeconomic transition.",Vojnosanitetski pregled,,0042-8450 0042-8450,,,"BACKGROUND/AIM: Recent studies have shown that biological treatments for rheumatoid arthritis can change the course of rheumatoid arthritis and improve functional ability of patients with rheumatoid arthritis. In spite of this fact, use of biological therapy is still limited by high prices of these medicines, especially in countries in socioeconomic transition. The aim of our study was to compare cost-effectiveness of a combination of tocilizumab and methotrexate with methotrexate alone for rheumatoid arthritis in Serbia, a country in socioeconomic transition. METHODS: For the purpose of our study we designed a Markov model using data on therapy efficacy from the available literature, and data on the costs of health states calculated from records of actual patients treated in the Clinical Center Kragujevac, Serbia. The duration of one cycle in our model was set at one month, and the time horizon was 480 months (40 years). The study was done from the social perspective, and all the costs and outcomes were discounted for 3% per year. RESULTS: Treating rheumatoid arthritis with disease-modifying antirheumatic drugs (DMARDs) alone was more cost-effective in comparison with a combination of biologic treatment with tocilizumab and DMARDs. The total costs for treating a patient with DMARDs for one year were on average 261,945.42 RSD, or 2,497.70 Euro and the total costs for treatment with tocilizimab plus DMARDs were on average 1,959,217.44 RSD, or 18,659.20 Euro. However, these results are susceptible to changes in costs and treatment effects of tocilizumab in patients with more severe forms of rheumatoid arthritis. CONCLUSION: Our results show that the use of tocilizumab for rheumatoid arthrits in economic environment of Serbia is not cost-effective. Use of tocilizumab for treating rheumatoid arthritis can become affordable, if costs of its use become lower. In order to start using expensive biologic medicines in patients in transitional countries, special strategy and pricing policy of international pharmaceutical companies are necessary, which would include calculation of prices of biologic medicines on the basis of local pharmacoeconomic studies.",2014-02,26/11/2018 12:52,14/04/2020 08:34,,144-148,,2,71,,Vojnosanit Pregl,,,,,,,,eng,,,,,,,PMID: 24665571,,,,"Humans; Socioeconomic Factors; *Cost-Benefit Analysis; Markov Chains; Arthritis, Rheumatoid/*drug therapy; Antibodies, Monoclonal, Humanized/*economics/therapeutic use; Antirheumatic Agents/*economics/therapeutic use; Drug Therapy, Combination; Methotrexate/*economics/therapeutic use; Serbia; 00; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YE59W3WJ,journalArticle,2016,"Dorjee, S.; Revie, C. W.; Poljak, Z.; McNab, W. B.; Sanchez, J.",One-Health Simulation Modelling: A Case Study of Influenza Spread between Human and Swine Populations using NAADSM.,Transboundary and emerging diseases,,1865-1682 1865-1674,10.1111/tbed.12215,,"The circulation of zoonotic influenza A viruses including pH1N1 2009 and H5N1 continue to present a constant threat to animal and human populations. Recently, an H3N2 variant spread from pigs to humans and between humans in limited numbers. Accordingly, this research investigated a range of scenarios of the transmission dynamics of pH1N1 2009 virus at the swine-human interface while accounting for different percentages of swine workers initially immune. Furthermore, the feasibility of using NAADSM (North American Animal Disease Spread Model) applied as a one-health simulation model was assessed. The study population included 488 swine herds and 29, 707 households of people within a county in Ontario, Canada. Households were categorized as follows: (i) rural households with swine workers, (ii) rural households without swine workers, and (iii) urban households without swine workers. Forty-eight scenarios were investigated, based on the combination of six scenarios around the transmissibility of the virus at the interface and four vaccination coverage levels of swine workers (0-60%), all under two settings of either swine or human origin of the virus. Outcomes were assessed in terms of stochastic 'die-out' fraction, size and time to peak epidemic day, overall size and duration of the outbreaks. The modelled outcomes indicated that minimizing influenza transmissibility at the interface and targeted vaccination of swine workers had significant beneficial effects. Our results indicate that NAADSM can be used as a framework to model the spread and control of contagious zoonotic diseases among animal and human populations, under certain simplifying assumptions. Further evaluation of the model is required. In addition to these specific findings, this study serves as a benchmark that can provide useful input to a future one-health influenza modelling studies. Some pertinent information gaps were also identified. Enhanced surveillance and the collection of high-quality information for more accurate parameterization of such models are encouraged.",2016-02,26/11/2018 12:52,14/04/2020 08:34,,36-55,,1,63,,Transbound Emerg Dis,,,,,,,,eng,(c) 2014 Blackwell Verlag GmbH.,,,,,,PMID: 24661802,,,,"Humans; Animals; 00; Ontario/epidemiology; humans; influenza; modelling; NAADSM; pigs; Swine; Agricultural Workers' Diseases/epidemiology/virology; Disease Outbreaks/*veterinary; Influenza A Virus, H1N1 Subtype/*isolation & purification; Influenza, Human/*epidemiology/transmission/virology; one health; Orthomyxoviridae Infections/*epidemiology/transmission/veterinary/virology; Swine Diseases/epidemiology/transmission/*virology; Vaccination; zoonoses; Zoonoses/epidemiology/virology; zoonotic; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DQXDFF66,journalArticle,2014,"Vataire, Anne-Lise; Aballea, Samuel; Antonanzas, Fernando; Roijen, Leona Hakkaart-van; Lam, Raymond W.; McCrone, Paul; Persson, Ulf; Toumi, Mondher",Core discrete event simulation model for the evaluation of health care technologies in major depressive disorder.,Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research,,1524-4733 1098-3015,10.1016/j.jval.2013.11.012,,"OBJECTIVE: A review of existing economic models in major depressive disorder (MDD) highlighted the need for models with longer time horizons that also account for heterogeneity in treatment pathways between patients. A core discrete event simulation model was developed to estimate health and cost outcomes associated with alternative treatment strategies. METHODS: This model simulated short- and long-term clinical events (partial response, remission, relapse, recovery, and recurrence), adverse events, and treatment changes (titration, switch, addition, and discontinuation) over up to 5 years. Several treatment pathways were defined on the basis of fictitious antidepressants with three levels of efficacy, tolerability, and price (low, medium, and high) from first line to third line. The model was populated with input data from the literature for the UK setting. Model outputs include time in different health states, quality-adjusted life-years (QALYs), and costs from National Health Service and societal perspectives. The codes are open source. RESULTS: Predicted costs and QALYs from this model are within the range of results from previous economic evaluations. The largest cost components from the payer perspective were physician visits and hospitalizations. Key parameters driving the predicted costs and QALYs were utility values, effectiveness, and frequency of physician visits. Differences in QALYs and costs between two strategies with different effectiveness increased approximately twofold when the time horizon increased from 1 to 5 years. CONCLUSION: The discrete event simulation model can provide a more comprehensive evaluation of different therapeutic options in MDD, compared with existing Markov models, and can be used to compare a wide range of health care technologies in various groups of patients with MDD.",2014-03,26/11/2018 12:52,14/04/2020 08:34,,183-195,,2,17,,Value Health,,,,,,,,eng,Copyright (c) 2014 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.,,,,,,PMID: 24636376,,,,"Humans; Quality-Adjusted Life Years; *Models, Economic; Markov Chains; Computer Simulation; cost-effectiveness; Time Factors; United Kingdom; discrete event simulation; Discrete event simulation; Hospitalization/economics; Biomedical Technology/*economics; antidepressants; Antidepressive Agents/adverse effects/economics/*therapeutic use; depression; Depressive Disorder, Major/*drug therapy/economics; Physicians/economics; Technology Assessment, Biomedical/methods; Link to community resources; X",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TKD4E4Q4,journalArticle,2014,"Karnon, Jonathan; Haji Ali Afzali, Hossein",When to use discrete event simulation (DES) for the economic evaluation of health technologies? A review and critique of the costs and benefits of DES.,PharmacoEconomics,,1179-2027 1170-7690,10.1007/s40273-014-0147-9,,"Modelling in economic evaluation is an unavoidable fact of life. Cohort-based state transition models are most common, though discrete event simulation (DES) is increasingly being used to implement more complex model structures. The benefits of DES relate to the greater flexibility around the implementation and population of complex models, which may provide more accurate or valid estimates of the incremental costs and benefits of alternative health technologies. The costs of DES relate to the time and expertise required to implement and review complex models, when perhaps a simpler model would suffice. The costs are not borne solely by the analyst, but also by reviewers. In particular, modelled economic evaluations are often submitted to support reimbursement decisions for new technologies, for which detailed model reviews are generally undertaken on behalf of the funding body. This paper reports the results from a review of published DES-based economic evaluations. Factors underlying the use of DES were defined, and the characteristics of applied models were considered, to inform options for assessing the potential benefits of DES in relation to each factor. Four broad factors underlying the use of DES were identified: baseline heterogeneity, continuous disease markers, time varying event rates, and the influence of prior events on subsequent event rates. If relevant, individual-level data are available, representation of the four factors is likely to improve model validity, and it is possible to assess the importance of their representation in individual cases. A thorough model performance evaluation is required to overcome the costs of DES from the users' perspective, but few of the reviewed DES models reported such a process. More generally, further direct, empirical comparisons of complex models with simpler models would better inform the benefits of DES to implement more complex models, and the circumstances in which such benefits are most likely.",2014-06,26/11/2018 12:52,14/04/2020 08:34,,547-558,,6,32,,Pharmacoeconomics,,,,,,,,eng,,,,,,,PMID: 24627341,,,,"Humans; Cost-Benefit Analysis; *Models, Economic; Cohort Studies; Decision Support Techniques; Time Factors; Disease Progression; 00; Biomedical Technology/*economics; ******To read; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, B443MIL5,journalArticle,2014,"Doolen, Jessica; Giddings, Michelle; Johnson, Michael; Guizado de Nathan, Gigi; O Badia, Lysander",An evaluation of mental health simulation with standardized patients.,International journal of nursing education scholarship,,1548-923X 1548-923X,10.1515/ijnes-2013-0075,,"Interviewing standardized patients (SPs) trained to model psychiatric disorders can promote student nurses' interview skills and therapeutic communication, while at the same time increasing their confidence and decreasing anxiety. From a constructivist view of education and Kolb's (1984; Experiential learning: Experience as the source of learning and development. Edgewood Cliffs, NJ: Prentice-Hall) theory of experiential learning, this article describes the development and use of SPs as a learning strategy. The use of SPs helps faculty in overcoming some of the challenges of competing for clinical sites and meeting objectives in limited clinical time. In this simulation, baccalaureate nursing students had the opportunity to interact with SPs, who had been trained to demonstrate symptoms of bipolar disorder, anxiety, and schizophrenia. During debriefing, students critiqued their performances, identifying strengths and weaknesses. The advantage to nursing students was the ability to improve their interviewing skills in a safe educational environment before encountering these patients in a clinical experience. Both faculty and student evaluations of this experience support its integration into psychiatric undergraduate courses.",12/03/2014,26/11/2018 12:52,14/04/2020 08:34,,,,,11,,Int J Nurs Educ Scholarsh,,,,,,,,eng,,,,,,,PMID: 24620017,,,,"Humans; Canada; Nursing Education Research; *Patient Simulation; Curriculum; Psychiatric Nursing/*education; Models, Educational; 00; *Education, Nursing, Graduate; Learning Curve; Social Environment; Faculty, Nursing/*supply & distribution; Mental Disorders/diagnosis/*nursing/therapy; Nurse Practitioners/education; Personnel Turnover; Social Identification; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, B9NXEZAI,journalArticle,2014,"Coyle, Joseph R.; Kaye, Keith S.; Taylor, Thomas; Tansek, Ryan; Campbell, Michelle; Hayakawa, Kayoko; Marchaim, Dror",Effectiveness and cost of implementing an active surveillance screening policy for Acinetobacter baumannii: a Monte Carlo simulation model.,American journal of infection control,,1527-3296 0196-6553,10.1016/j.ajic.2013.09.027,,"BACKGROUND: Acinetobacter baumannii infections are common and associated with high mortality and costs. Early identification of asymptomatic carriers can reduce patient-to-patient transmission, but the sensitivity of A baumannii surveillance tools is poor, and thus active surveillance is not routine practice. This study examined whether an active surveillance screening policy can reduce the transmission, mortality, and costs associated with A baumannii. METHODS: A simulation model was developed to determine the impact of active screening on patient outcomes. Model parameters included A baumannii prevalence, screening sensitivity and specificity, probability of transmission, progression from colonization to infection, mortality, and cost of screening, contact precautions, and infection. A scenario analysis was performed to evaluate the robustness of the results when varying the sensitivity of the screening test and the prevalence rate of A baumannii. RESULTS: Assuming a screening sensitivity of 55%, active screening reduced A baumannii transmissions, infections, and deaths by 48%. As the screening sensitivity approached 90%, the reduction in transmissions, infections, and deaths reached 78%. For all scenarios tested, active surveillance was cost saving (19%-53% reduction in mean hospital cost per patient) except at a carrier prevalence of 35 kg/m2, gastric bypass renders 1.9 extra QALYs and saves on average 13,244euro per patient. Younger patients, patients with a BMI between 40 and 50 kg/m2, and patients without obesity-related diseases are the ones with a bigger benefit in terms of cost effectiveness. CONCLUSIONS: Gastric bypass surgery increases quality-adjusted survival and saves resources to health systems. As such, it can be an important process to control the ever-increasing health expenditure.",2013-04,26/11/2018 12:52,14/04/2020 08:34,,460-466,,4,23,,Obes Surg,,,,,,,,eng,,,,,,,PMID: 23341033,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Adult; Female; Male; *Models, Economic; *Markov Chains; Comorbidity; Health Expenditures; Body Mass Index; 00; Diabetes Mellitus, Type 2/*economics/surgery; Gastric Bypass/*economics; Gastroplasty/*economics; Obesity, Morbid/*economics/surgery; Portugal; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TFN7KVSE,journalArticle,2013,"Koh, Howard K.; Baur, Cynthia; Brach, Cindy; Harris, Linda M.; Rowden, Jessica N.",Toward a systems approach to health literacy research.,Journal of health communication,,1087-0415 1081-0730,10.1080/10810730.2013.759029,,,2013,26/11/2018 12:52,14/04/2020 08:34,,01-May,,1,18,,J Health Commun,,,,,,,,eng,,,,,,,PMID: 23305507 PMCID: PMC5127593,,,,Delivery of Health Care/*organization & administration; Humans; United States; Patient-Centered Care; Health Services Research/*methods; Patient Protection and Affordable Care Act; 00; *Health Literacy; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EX3UK77U,journalArticle,2012,"Wang, Nuo; Zhang, Zhan-Jun; Chang, Dong",[Using markov model to cost-effectiveness analysis of traditional Chinese medicine interference].,Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica,,1001-5302 1001-5302,,,"Mild cognitive impairment (MCI) is the transition state between normal aging and AD. There are better detection and treatment methods to screen a population of patients with MCI. Through intervention, the probability of MCI conversion to AD can be significantly reduced. This paper first introduces the concept of cost-effectiveness analysis, reconsiders the concept of cost for the particularity of MCI, and uses QALY to evaluate the health effects of the quality of life. Then measure the health quality of life of elderly MCI population, and use Markov model to study the cost of intervention with traditional Chinese medicine-effectiveness analysis. Finally, according to the QALY measure and CEA results, we draw the conclusion that it's helpful to get early intervention in MCI.",2012-09,26/11/2018 12:52,14/04/2020 08:35,,2698-2701,,18,37,,Zhongguo Zhong Yao Za Zhi,,,,,,,,chi,,,,,,,PMID: 23285912,,,,"Humans; Cost-Benefit Analysis; Markov Chains; Alzheimer Disease/drug therapy/*economics; 00; Cognitive Dysfunction/drug therapy/*economics; Drugs, Chinese Herbal/*economics/therapeutic use; Medicine, Chinese Traditional/*economics; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, U4T5BHBI,journalArticle,2012,"Rosen, Michael A.; Hunt, Elizabeth A.; Pronovost, Peter J.; Federowicz, Molly A.; Weaver, Sallie J.",In situ simulation in continuing education for the health care professions: a systematic review.,The Journal of continuing education in the health professions,,1554-558X 0894-1912,10.1002/chp.21152,,"INTRODUCTION: Education in the health sciences increasingly relies on simulation-based training strategies to provide safe, structured, engaging, and effective practice opportunities. While this frequently occurs within a simulation center, in situ simulations occur within an actual clinical environment. This blending of learning and work environments may provide a powerful method for continuing education. However, as this is a relatively new strategy, best practices for the design and delivery of in situ learning experiences have yet to be established. This article provides a systematic review of the in situ simulation literature and compares the state of the science and practice against principles of effective education and training design, delivery, and evaluation. METHODS: A total of 3190 articles were identified using academic databases and screened for descriptive accounts or studies of in situ simulation programs. Of these, 29 full articles were retrieved and coded using a standard data extraction protocol (kappa = 0.90). RESULTS: In situ simulations have been applied to foster individual, team, unit, and organizational learning across several clinical and nonclinical areas. Approaches to design, delivery, and evaluation of the simulations were highly variable across studies. The overall quality of in situ simulation studies is low. A positive impact of in situ simulation on learning and organizational performance has been demonstrated in a small number of studies. DISCUSSION: The evidence surrounding in situ simulation efficacy is still emerging, but the existing research is promising. Practical program planning strategies are evolving to meet the complexity of a novel learning activity that engages providers in their actual work environment.",2012,26/11/2018 12:52,14/04/2020 08:35,,243-254,,4,32,,J Contin Educ Health Prof,,,,,,,,eng,"Copyright (c) 2012 The Alliance for Continuing Education in the Health Professions, the Society for Academic Continuing Medical Education, and the Council on CME, Association for Hospital Medical Education.",,,,,,PMID: 23280527,,,,"Humans; *Patient Simulation; Education, Medical, Continuing/*methods; Problem-Based Learning/*methods; *Program Evaluation; 00; Education, Distance; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DXI59GDI,journalArticle,2013,"Cordioli, Michele; Vincenzi, Simone; De Leo, Giulio A.",Effects of heat recovery for district heating on waste incineration health impact: a simulation study in Northern Italy.,The Science of the total environment,,1879-1026 0048-9697,10.1016/j.scitotenv.2012.11.079,,"The construction of waste incinerators in populated areas always causes substantial public concern. Since the heat from waste combustion can be recovered to power district heating networks and allows for the switch-off of domestic boilers in urbanized areas, predictive models for health assessment should also take into account the potential benefits of abating an important source of diffuse emission. In this work, we simulated the dispersion of atmospheric pollutants from a waste incinerator under construction in Parma (Italy) into different environmental compartments and estimated the potential health effect of both criteria- (PM(10)) and micro-pollutants (PCDD/F, PAH, Cd, Hg). We analyzed two emission scenarios, one considering only the new incinerator, and the other accounting for the potential decrease in pollutant concentrations due to the activation of a district heating network. We estimated the effect of uncertainty in parameter estimation on health risk through Monte Carlo simulations. In addition, we analyzed the robustness of health risk to alternative assumptions on: a) the geographical origins of the potentially contaminated food, and b) the dietary habits of the exposed population. Our analysis showed that under the specific set of assumptions and emission scenarios explored in the present work: (i) the proposed waste incinerator plant appears to cause negligible harm to the resident population; (ii) despite the net increase in PM(10) mass balance, ground-level concentration of fine particulate matter may be curbed by the activation of an extensive district heating system powered through waste combustion heat recovery and the concurrent switch-off of domestic/industrial heating boilers. In addition, our study showed that the health risk caused by waste incineration emissions is sensitive to assumptions about the typical diet of the resident population, and the geographical origins of food production.",01/02/2013,26/11/2018 12:52,14/04/2020 08:34,,369-380,,,444,,Sci Total Environ,,,,,,,,eng,Copyright (c) 2012 Elsevier B.V. All rights reserved.,,,,,,PMID: 23280295,,,,Humans; *Public Health; Computer Simulation; Italy; 00; *Incineration; Air Pollutants/*analysis/*toxicity; Air Pollution/analysis; Cadmium/analysis/toxicity; Heating; Hot Temperature; Mercury/analysis/toxicity; Particulate Matter/analysis/toxicity; Polycyclic Aromatic Hydrocarbons/analysis/toxicity; Refuse Disposal/methods; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VA8UEMYV,journalArticle,2012,"Whitley, Heather P.",Active-learning diabetes simulation in an advanced pharmacy practice experience to develop patient empathy.,American journal of pharmaceutical education,,1553-6467 0002-9459,10.5688/ajpe7610203,,"OBJECTIVE: To develop and integrate an active-learning diabetes simulation into an advanced pharmacy practice experience to improve pharmacy students' empathy toward patients with diabetes mellitus. DESIGN: Students simulated the experience of having diabetes mellitus by conducting activities commonly prescribed to those with this disease state for 7 days, after which they submitted a standardized diabetes log and narrative reflection. Interpretive phenomenology design with thematic analysis was used to determine the impact of this experience on the students. ASSESSMENT: As shown in student reflections, 95% developed empathy, 97% found the experience beneficial, and 67% improved their ability to relate to and counsel patients. Most (95%) found difficulty adhering to the regimen. On average, students consumed 179 grams of carbohydrates per day and exercised 5 days or 215 minutes per week. Additionally, 69% decided to modify their personal habits to become healthier. CONCLUSIONS: Inclusion of the 7-day active-learning exercise greatly impacted student pharmacists' self-reported empathy toward and ability to relate to patients with diabetes mellitus. Completion of this experience may result in long-lasting personal behavior modifications.",12/12/2012,26/11/2018 12:52,14/04/2020 08:35,,203,,10,76,,Am J Pharm Educ,,,,,,,,eng,,,,,,,PMID: 23275668 PMCID: PMC3530065,,,,"Humans; *Curriculum; Female; Male; *Empathy; public health; *Attitude of Health Personnel; simulation; Professional-Patient Relations; *Problem-Based Learning; active learning; 00; Education, Pharmacy/*methods; Students, Pharmacy/*psychology; advanced pharmacy practice experience; diabetes mellitus; Diabetes Mellitus/*psychology; empathy; Pharmacies; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5Z93PPQL,journalArticle,2013,"Zhou, Yuan; Ancker, Jessica S.; Upadhye, Mandar; McGeorge, Nicolette M.; Guarrera, Theresa K.; Hegde, Sudeep; Crane, Peter W.; Fairbanks, Rollin J.; Bisantz, Ann M.; Kaushal, Rainu; Lin, Li",The impact of interoperability of electronic health records on ambulatory physician practices: a discrete-event simulation study.,Informatics in primary care,,1475-9985 1475-9985,10.14236/jhi.v21i1.36,,"BACKGROUND: The effect of health information technology (HIT) on efficiency and workload among clinical and nonclinical staff has been debated, with conflicting evidence about whether electronic health records (EHRs) increase or decrease effort. None of this paper to date, however, examines the effect of interoperability quantitatively using discrete event simulation techniques. OBJECTIVE: To estimate the impact of EHR systems with various levels of interoperability on day-to-day tasks and operations of ambulatory physician offices. METHODS: Interviews and observations were used to collect workflow data from 12 adult primary and specialty practices. A discrete event simulation model was constructed to represent patient flows and clinical and administrative tasks of physicians and staff members. RESULTS: High levels of EHR interoperability were associated with reduced time spent by providers on four tasks: preparing lab reports, requesting lab orders, prescribing medications, and writing referrals. The implementation of an EHR was associated with less time spent by administrators but more time spent by physicians, compared with time spent at paper-based practices. In addition, the presence of EHRs and of interoperability did not significantly affect the time usage of registered nurses or the total visit time and waiting time of patients. CONCLUSION: This paper suggests that the impact of using HIT on clinical and nonclinical staff work efficiency varies, however, overall it appears to improve time efficiency more for administrators than for physicians and nurses.",2013,26/11/2018 12:52,14/04/2020 08:34,,21-29,,1,21,,Inform Prim Care,,,,,,,,eng,,,,,,,PMID: 24629653,,,,"Humans; Qualitative Research; *Computer Simulation; Monte Carlo Method; Electronic Health Records/*organization & administration; *Systems Integration; 1; *Workflow; Ambulatory Care Facilities/organization & administration; Practice Management, Medical/*organization & administration; ******To read; Discrete event; X",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, D2678B9I,journalArticle,2013,"Jacklin, P.; Duckett, J.",A decision-analytic Markov model to compare the cost-utility of anterior repair augmented with synthetic mesh compared with non-mesh repair in women with surgically treated prolapse.,BJOG : an international journal of obstetrics and gynaecology,,1471-0528 1470-0328,10.1111/1471-0528.12028,,"OBJECTIVES: To assess the cost-effectiveness of a mesh-augmented anterior vaginal wall repair compared with a non-mesh fascial plication repair. DESIGN: Cost-utility analysis. SETTING: Data for outcomes of different surgical techniques were derived from systematic reviews and recent publications. METHODS: A decision-analytic Markov model, developed in TreeAge Pro 2007((R)) , was used to compare the cost-utility of mesh and non-mesh anterior vaginal wall repairs. Sensitivity analysis was used to assess the impact of different scenarios and assumptions on results from the model. MAIN OUTCOME MEASURE: Health outcomes were expressed in terms of quality-adjusted life years (QALYs). RESULTS: Under base case assumptions at 5 years, the incremental cost-effectiveness ratio (ICER) for mesh-augmented anterior repairs was pound15 million per QALY. Sensitivity analysis found no plausible model inputs that could make a mesh repair cost-effective by conventional criteria. This was mostly because of the extra costs associated with the price of the mesh, treating mesh erosion and difficulty finding data that support a lower reoperation rate for mesh anterior wall repairs. CONCLUSIONS: This model suggests that the use of mesh is not cost-effective.",2013-01,26/11/2018 12:52,14/04/2020 08:34,,217-223,,2,120,,BJOG,,,,,,,,eng,(c) 2013 The Authors BJOG An International Journal of Obstetrics and Gynaecology (c) 2013 RCOG.,,,,,,PMID: 23240800,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Treatment Outcome; Health Care Costs; Female; Markov Chains; Models, Statistical; United Kingdom; Models, Economic; Recurrence; 00; Reoperation/economics; Gynecologic Surgical Procedures/*economics/instrumentation/methods; Pelvic Organ Prolapse/economics/*surgery; Postoperative Complications/economics; Surgical Mesh/*economics; Vagina/*surgery; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, A97524QW,journalArticle,2013,"Alfonso, E.; Xie, X.; Augusto, V.; Garraud, O.",Modelling and simulation of blood collection systems: improvement of human resources allocation for better cost-effectiveness and reduction of candidate donor abandonment.,Vox sanguinis,,1423-0410 0042-9007,10.1111/vox.12001,,"BACKGROUND: This study addresses the modelling and simulation of blood collection for fixed blood collection sites in a medium-sized large French city, as well as mobile blood collection in urban and rural environments. STUDY DESIGN AND METHODS: Formal Petri net models were used to describe all relevant donor flows of the various blood collection systems; the Petri net models were converted onto discrete-event simulation models, allowing the evaluation of a large number of scenarios and configurations of blood collection systems. Quantitative models were proposed that encompassed all components of the blood collection systems, such as the donor arrival process, resource capacities and performance indicators. Appropriate experimental designs and cost-effectiveness analyses were used to determine the best configurations of human resources and donor appointment strategies. RESULTS: The donor service level depended on both adequate human resources capacity and appropriate appointment strategies. These decisions depend on the distribution during the day of walk-in donors. CONCLUSION: Models permit to improve management of blood collection; they have now partially entered the real situation, awaiting further implementation.",2013-04,26/11/2018 12:52,14/04/2020 08:34,,225-233,,3,104,,Vox Sang,,,,,,,,eng,(c) 2012 The Author(s). Vox Sanguinis (c) 2012 International Society of Blood Transfusion.,,,,,,PMID: 23216456,,,,"France; Humans; Cost-Benefit Analysis; Computer Simulation; Resource Allocation; Algorithms; Models, Theoretical; Time Factors; Probability; 00; transfusion; *Blood Donors; blood donor flow management; Blood Transfusion/economics/*methods; discrete-event simulation; health system cost-effectiveness; petri nets; Transfusion Medicine/economics/*organization & administration; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EI7NUHHA,journalArticle,2013,"Lonati, Giovanni; Zanoni, Francesca",Monte-Carlo human health risk assessment of mercury emissions from a MSW gasification plant.,"Waste management (New York, N.Y.)",,1879-2456 0956-053X,10.1016/j.wasman.2012.10.015,,"The potential impact of the atmospheric emission of mercury from a new waste gasification plant is assessed by means of a probabilistic approach based on probability density functions for the description of the input data (namely, emission rate of mercury gaseous and particulate species) and the model parameters involved in the individual risk exposure assessment through the pathways of inhalation, soil ingestion, dermal contact, and diet. The use of probability functions allowed the uncertainty in the input data and model parameters to be accounted for; the uncertainty was propagated throughout the evaluation by Monte Carlo technique, resulting in the probability distributions for the ambient air and soil concentrations nearby the plant and for the subsequent individual risk, estimated in terms of hazard index for both an adult and a child receptor. The estimated median concentration levels in air and soil are respectively in the 1.6 x 10(-3)-2.2 x 10(-2) ng m(-3) range and in the 3.5 x 10(-4)-1.7 x 10(-2) mg kg(-1) range, that is at least two orders of magnitude lower than the current background concentration in the ambient air and one order of magnitude lower than the concentration locally measured in the soil. The diet pathway is responsible for the most part (>80%) of the daily mercury intake, which, however, is at least four (median estimated values) and three orders (estimates for a reasonable maximum exposure) lower than the reference dose in the most part of the modeling domain. According to the locally measured background mercury levels in air and soil the additional contribution of the plant emissions to the environmental mercury levels appears of small significance, with an almost negligible impact on the hazard index for the population living in the neighborhood of the plant.",2013-02,26/11/2018 12:52,14/04/2020 08:34,,347-355,,2,33,,Waste Manag,,,,,,,,eng,Copyright (c) 2012 Elsevier Ltd. All rights reserved.,,,,,,PMID: 23177017,,,,"Humans; Adult; Child; Monte Carlo Method; Models, Theoretical; Risk Assessment/methods; Italy; 00; *Environmental Exposure; *Refuse Disposal; Air Pollutants/analysis/chemistry/*toxicity; Environmental Monitoring/*methods; Mercury/analysis/chemistry/*toxicity; Soil Pollutants/analysis/chemistry/*toxicity; Volatilization; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RFUBWP4K,journalArticle,2012,"Gurieva, Tatiana V.; Bootsma, Martin C. J.; Bonten, Marc J. M.",Decolonization of patients and health care workers to control nosocomial spread of methicillin-resistant Staphylococcus aureus: a simulation study.,BMC infectious diseases,,1471-2334 1471-2334,10.1186/1471-2334-12-302,,"BACKGROUND: Control of methicillin-resistant Staphylococcus aureus (MRSA) transmission has been unsuccessful in many hospitals. Recommended control measures include isolation of colonized patients, rather than decolonization of carriage among patients and/or health care workers. Yet, the potential effects of such measures are poorly understood. METHODS: We use a stochastic simulation model in which health care workers can transmit MRSA through short-lived hand contamination, or through persistent colonization. Hand hygiene interrupts the first mode, decolonization strategies the latter. We quantified the effectiveness of decolonization of patients and health care workers, relative to patient isolation in settings where MRSA carriage is endemic (rather than sporadic outbreaks in non-endemic settings caused by health care workers). RESULTS: Patient decolonization is the most effective intervention and outperforms patient isolation, even with low decolonization efficacy and when decolonization is not achieved immediately. The potential role of persistently colonized health care workers in MRSA transmission depends on the proportion of persistently colonized health care workers and the likelihood per colonized health care worker to transmit. As stand-alone intervention, universal screening and decolonization of persistently colonized health care workers is generally the least effective intervention, especially in high endemicity settings. When added to patient isolation, such a strategy would have maximum benefits if few health care workers cause a large proportion of the acquisitions. CONCLUSIONS: In high-endemicity settings regular screening of health care workers followed by decolonization of",14/11/2012,26/11/2018 12:52,14/04/2020 08:34,,302,,,12,,BMC Infect Dis,,,,,,,,eng,,,,,,,PMID: 23151152 PMCID: PMC3526562,,,,"Humans; Models, Statistical; *Health Personnel; Cross Infection/*prevention & control; Disease Transmission, Infectious/*prevention & control; 1; *Patients; Carrier State/*drug therapy/microbiology; Methicillin-Resistant Staphylococcus aureus/*drug effects; Staphylococcal Infections/*drug therapy/microbiology/prevention & control/transmission; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GMNAX32N,journalArticle,2012,"Crowcroft, Natasha S.; Hamid, Jemila S.; Deeks, Shelley L.; Frank, John",Human papilloma virus vaccination programs reduce health inequity in most scenarios: a simulation study.,BMC public health,,1471-2458 1471-2458,10.1186/1471-2458-12-935,,"BACKGROUND: The global and within-country epidemiology of cervical cancer exemplifies health inequity. Public health programs may reduce absolute risk but increase inequity; inequity may be further compounded by screening programs. In this context, we aimed to explore what the impact of human papillomavirus (HPV) vaccine might have on health equity allowing for uncertainty surrounding the long-term effect of HPV vaccination programs. METHODS: A simple static multi-way sensitivity analysis was carried out to compare the relative risk, comparing after to before implementation of a vaccination program, of infections which would cause invasive cervical cancer if neither prevented nor detected, using plausible ranges of vaccine effectiveness, vaccination coverage, screening sensitivity, screening uptake and changes in uptake. RESULTS: We considered a total number of 3,793,902 scenarios. In 63.9% of scenarios considered, vaccination would lead to a better outcome for a population or subgroup with that combination of parameters. Regardless of vaccine effectiveness and coverage, most simulations led to lower rates of disease. CONCLUSIONS: If vaccination coverage and screening uptake are high, then communities are always better off with a vaccination program. The findings highlight the importance of achieving and maintaining high immunization coverage and screening uptake in high risk groups in the interest of health equity.",31/10/2012,26/11/2018 12:52,14/04/2020 08:34,,935,,,12,,BMC Public Health,,,,,,,,eng,,,,,,,PMID: 23113881 PMCID: PMC3529110,,,,"Humans; Program Evaluation; Female; Computer Simulation; Models, Theoretical; Risk Assessment/methods; *Immunization Programs; *Health Status Disparities; 00; Early Detection of Cancer/utilization; Papillomavirus Infections/*prevention & control; Papillomavirus Vaccines/*administration & dosage; Uterine Cervical Neoplasms/*prevention & control; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Q9BI7FS6,journalArticle,2012,"Cobb, Rachel K.",How well does spirituality predict health status in adults living with,Nursing science quarterly,,1552-7409 0894-3184,10.1177/0894318412457051,,"The purpose of this study was to examine the relationship between spirituality and health status of 39 adult men and women living with HIV-disease. A model building approach was used to explore the associations among the five variables of the Neuman systems model, which was the guiding framework for the study. The model presented includes existential well-being, meaningfulness, age, and income.",2012-10,26/11/2018 12:52,14/04/2020 08:34,,347-355,,4,25,,Nurs Sci Q,,,,,,,,eng,,,,,,,PMID: 23087344,,,,"Humans; Female; Male; *Health Status; *Models, Theoretical; 00; *Spirituality; HIV Infections/*physiopathology; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LKGN4NKQ,journalArticle,2013,"Skoldunger, Anders; Johnell, Kristina; Winblad, Bengt; Wimo, Anders",Mortality and treatment costs have a great impact on the cost-effectiveness of disease modifying treatment in Alzheimer's disease--a simulation study.,Current Alzheimer research,,1875-5828 1567-2050,,,"BACKGROUND: The societal costs of Alzheimer's Disease (AD) are enormous and pose a great challenge for the health and social care in any society. It is of vital importance to develop and identify cost effective treatment. The aim of the study was to present a hypothetical economic model of Disease Modifying Treatment (DMT) in AD. METHODS: A 20 year Markov cohort model of DMT was constructed, based on Swedish care conditions. States and progression were defined according to the Mini Mental State Examination (MMSE). Epidemiological studies of incidence of dementia, prevalence and costs of Mild Cognitive Impairment (MCI) and AD as well as conversion studies of MCI and demographic statistics were used as inputs in the model. RESULTS: Total costs were 113,797 million SEK for patients treated with DMT vs 88,562 million SEK for untreated patients. The corresponding gained QALYs were 529,945 and 450,307 respectively, giving an incremental cost effectiveness ratio of 293,002 SEK/QALY in the base option. Survival in the model was 8.72 years with DMT and 7.77 years for untreated. With an assumed Willingness to pay (WTP) of 600,000 SEK (about 86,200 US$ and 62,000 ) per gained QALY, the model indicated cost effectiveness with DMT. The sensitivity analysis implied no cost savings with DMT, but most options indicated cost effectiveness vs. the chosen WTP. CONCLUSION: The main reasons for the higher costs with DMT were the costs of DMT itself and the prolonged survival with DMT. Even if costs increase with DMT, the model indicates cost effectiveness.",2013-02,26/11/2018 12:52,14/04/2020 08:35,,207-216,,2,10,,Curr Alzheimer Res,,,,,,,,eng,,,,,,,PMID: 23036018,,,,"Humans; Female; Male; Markov Chains; *Disease Management; *Models, Theoretical; Longitudinal Studies; Kaplan-Meier Estimate; Sweden/epidemiology; 00; Alzheimer Disease/*economics/epidemiology/*mortality/*therapy; Cognition Disorders/economics/epidemiology/therapy; Cost-Benefit Analysis/*economics; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, T3YB3UMD,journalArticle,2012,"David, Michael C.; Bensink, Mark; Higashi, Hideki; Donald, Maria; Alati, Rosa; Ware, Robert S.",Monte Carlo simulation of the cost-effectiveness of sample size maintenance programs revealed the need to consider substitution sampling.,Journal of clinical epidemiology,,1878-5921 0895-4356,10.1016/j.jclinepi.2012.04.013,,"OBJECTIVE: To assess the cost-effectiveness of sample size maintenance programs in a prospective cohort. STUDY DESIGN AND SETTING: The Living with Diabetes Study in Queensland, Australia is a longitudinal survey providing a comprehensive examination of health care utilization and disease progression among people with diabetes. Data from this study were used to compare the cost-effectiveness of a program incorporating substitution sampling with two alternative programs: ""no follow-up"" and ""usual practice."" RESULTS: A program involving substitution sampling was shown to be the most effective with an additional 3,556 complete responses (compared with a ""no follow-up"" program) and an additional 2,099 complete responses (compared with ""usual practice""). An incremental analysis through a Monte Carlo simulation found substitution sampling to be the most cost-effective option for maintaining sample size with an incremental cost-effective ratio of $54.87 (95% uncertainty interval $52.68-$57.25) compared with $87.58 ($77.89-$100.09) for ""usual practice."" CONCLUSIONS: Based on the available data, a program involving substitution sampling is economically justified and should be considered in any approach with the aim of maintaining sample size. There is, however, a continuing need to evaluate the effectiveness of this option on other outcome measures, such as bias.",2012-11,26/11/2018 12:52,14/04/2020 08:34,,1200-1211,,11,65,,J Clin Epidemiol,,,,,,,,eng,Copyright (c) 2012 Elsevier Inc. All rights reserved.,,,,,,PMID: 23017637,,,,Humans; Cost-Benefit Analysis; Decision Trees; Prospective Studies; Disease Progression; Queensland/epidemiology; *Monte Carlo Method; Diabetes Mellitus/epidemiology; Health Services/utilization; 00; *Sample Size; Health Care Surveys/*economics/methods; Patient Dropouts/statistics & numerical data; Reminder Systems/economics; Selection Bias; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WFJL9DEI,journalArticle,2012,"Jarris, Paul E.; Monroe, Judith A.; Pestronk, Robert M.",Better health requires partnerships and a systems approach.,American journal of public health,,1541-0048 0090-0036,10.2105/AJPH.2012.301018,,,2012-11,26/11/2018 12:52,14/04/2020 08:34,,e4; author reply e4-5,,11,102,,Am J Public Health,,,,,,,,eng,,,,,,,PMID: 22994284 PMCID: PMC3477939,,,,Humans; *Public Health; 00; *Environmental Health; Adolescent Health Services/*organization & administration; Sanitation/*standards; 100; ****more for intro,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3IG5KK5C,journalArticle,2012,"van Tilborg, Theodora C.; Eijkemans, Marinus J. C.; Laven, Joop S. E.; Koks, Carolien A. M.; de Bruin, Jan Peter; Scheffer, Gabrielle J.; van Golde, Ron J. T.; Fleischer, Kathrin; Hoek, Annemieke; Nap, Annemiek W.; Kuchenbecker, Walter K. H.; Manger, Petra A.; Brinkhuis, Egbert A.; van Heusden, Arne M.; Sluijmer, Alexander V.; Verhoeff, Arie; van Hooff, Marcel H. A.; Friederich, Jaap; Smeenk, Jesper M. J.; Kwee, Janet; Verhoeve, Harold R.; Lambalk, Cornelis B.; Helmerhorst, Frans M.; van der Veen, Fulco; Mol, Ben Willem J.; Torrance, Helen L.; Broekmans, Frank J. M.",The OPTIMIST study: optimisation of cost effectiveness through individualised FSH stimulation dosages for IVF treatment. A randomised controlled trial.,BMC women's health,,1472-6874 1472-6874,10.1186/1472-6874-12-29,,"BACKGROUND: Costs of in vitro fertilisation (IVF) are high, which is partly due to the use of follicle stimulating hormone (FSH). FSH is usually administered in a standard dose. However, due to differences in ovarian reserve between women, ovarian response also differs with potential negative consequences on pregnancy rates. A Markov decision-analytic model showed that FSH dose individualisation according to ovarian reserve is likely to be cost-effective in women who are eligible for IVF. However, this has never been confirmed in a large randomised controlled trial (RCT). The aim of the present study is to assess whether an individualised FSH dose regime based on an ovarian reserve test (ORT) is more cost-effective than a standard dose regime. METHODS/DESIGN: Multicentre RCT in subfertile women indicated for a first IVF or intracytoplasmic sperm injection cycle, who are aged < 44 years, have a regular menstrual cycle and no major abnormalities at transvaginal sonography. Women with polycystic ovary syndrome, endocrine or metabolic abnormalities and women undergoing IVF with oocyte donation, will not be included. Ovarian reserve will be assessed by measuring the antral follicle count. Women with a predicted poor response or hyperresponse will be randomised for a standard versus an individualised FSH regime (150 IU/day,",18/09/2012,26/11/2018 12:52,14/04/2020 08:35,,29,,,12,,BMC Womens Health,,,,,,,,eng,,,,,,,PMID: 22989359 PMCID: PMC3460731,,,,"Humans; Netherlands; Cost-Benefit Analysis; Treatment Outcome; Adult; Female; Decision Support Techniques; Pregnancy; Proportional Hazards Models; Drug Administration Schedule; Logistic Models; Multivariate Analysis; 00; Clinical Protocols; Drug Dosage Calculations; Fertilization in Vitro/economics/*methods; Follicle Stimulating Hormone/*administration & dosage/economics; Infertility, Female/economics/*therapy; Intention to Treat Analysis; Ovarian Follicle/physiology; Pregnancy Rate; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6X43U2UJ,journalArticle,2012,"Noury, N.; Hadidi, T.",Computer simulation of the activity of the elderly person living independently in a Health Smart Home.,Computer methods and programs in biomedicine,,1872-7565 0169-2607,10.1016/j.cmpb.2012.07.004,,"We propose a simulator of human activities collected with presence sensors in our experimental Health Smart Home ""Habitat Intelligent pour la Sante (HIS)"". We recorded 1492 days of data on several experimental HIS during the French national project ""AILISA"". On these real data, we built a mathematical model of the behavior of the data series, based on ""Hidden Markov Models"" (HMM). The model is then played on a computer to produce simulated data series with added flexibility to adjust the parameters in various scenarios. We also tested several methods to measure the similarity between our real and simulated data. Our simulator can produce large data base which can be further used to evaluate the algorithms to raise an alarm in case of loss in autonomy.",2012-12,26/11/2018 12:52,14/04/2020 08:35,,1216-1228,,3,108,,Comput Methods Programs Biomed,,,,,,,,eng,Copyright (c) 2012 Elsevier Ireland Ltd. All rights reserved.,,,,,,PMID: 22981436,,,,Humans; Aged; *Computer Simulation; 00; *Activities of Daily Living; Residential Facilities/*organization & administration; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HU45HGRP,journalArticle,2012,"Elliott, Lydia; DeCristofaro, Claire; Carpenter, Alesia",Blending technology in teaching advanced health assessment in a family nurse practitioner program: using personal digital assistants in a simulation laboratory.,Journal of the American Academy of Nurse Practitioners,,1745-7599 1041-2972,10.1111/j.1745-7599.2012.00728.x,,"PURPOSE: This article describes the development and implementation of integrated use of personal handheld devices (personal digital assistants, PDAs) and high-fidelity simulation in an advanced health assessment course in a graduate family nurse practitioner (NP) program. A teaching tool was developed that can be utilized as a template for clinical case scenarios blending these separate technologies. DATA SOURCES: Review of the evidence-based literature, including peer-reviewed articles and reviews. CONCLUSIONS: Blending the technologies of high-fidelity simulation and handheld devices (PDAs) provided a positive learning experience for graduate NP students in a teaching laboratory setting. Combining both technologies in clinical case scenarios offered a more real-world learning experience, with a focus on point-of-care service and integration of interview and physical assessment skills with existing standards of care and external clinical resources. Faculty modeling and advance training with PDA technology was crucial to success. IMPLICATIONS FOR PRACTICE: Faculty developed a general template tool and systems-based clinical scenarios integrating PDA and high-fidelity simulation. Faculty observations, the general template tool, and one scenario example are included in this article.",2012-09,26/11/2018 12:52,14/04/2020 08:34,,536-543,,9,24,,J Am Acad Nurse Pract,,,,,,,,eng,(c)2012 The Author(s) Journal compilation (c)2012 American Academy of Nurse Practitioners.,,,,,,PMID: 22931479,,,,"Humans; Nursing Evaluation Research; Education, Nursing/*methods; *Students, Nursing; Teaching/*methods; *Manikins; Professional Competence; 00; Point-of-Care Systems; Advanced Practice Nursing/*education/methods; Educational Technology/*methods; Family Nursing/*methods; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6459IYB5,journalArticle,2012,"Pinder-Amaker, Stephanie; Bell, Catherine",A bioecological systems approach for navigating the college mental health crisis.,Harvard review of psychiatry,,1465-7309 1067-3229,10.3109/10673229.2012.712842,,"McLean Hospital's College Mental Health Program was established four years ago as an institutional response to escalating, national college mental health concerns. The critical factors underlying the college mental health crisis in this country have been debated, examined, and addressed almost exclusively within college and university settings. McLean Hospital is the first psychiatric hospital to develop a comprehensive college student program that bridges the gap between a psychiatric hospital and multiple campus settings as an attempt to address the specific needs of college student-patients across levels of psychiatric care and diagnostic areas/programs. Using a bioecological systems framework, this review examines (1) the strategic clinical, education/outreach, and research efforts that collectively represent a paradigm shift to extend responsibility for addressing serious college mental health challenges beyond college and university campuses, (2) the challenges and benefits of creating stronger multi-campus/hospital collaborations in order to improve our understanding of college students with serious mental illness, and (3) the progress in addressing these needs more effectively and in establishing documented best practices and policies through effective and innovative partnerships.",2012-08,26/11/2018 12:52,14/04/2020 08:35,,174-188,,4,20,,Harv Rev Psychiatry,,,,,,,,eng,,,,,,,PMID: 22894727,,,,Humans; Health Policy; United States; Young Adult; Adolescent; Practice Guidelines as Topic; *Cooperative Behavior; *Interdisciplinary Communication; 00; Mental Disorders/epidemiology/*therapy; Mental Health Services/*organization & administration; Health Services Needs and Demand/*organization & administration; Health Services Research/*organization & administration; Student Health Services/*organization & administration; Students/*psychology; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6RFUFD7R,journalArticle,2013,"Di Mascolo, Maria; Gouin, Alexia",A generic simulation model to assess the performance of sterilization services in health establishments.,Health care management science,,1386-9620 1386-9620,10.1007/s10729-012-9210-2,,"The work presented here is with a view to improving performance of sterilization services in hospitals. We carried out a survey in a large number of health establishments in the Rhone-Alpes region in France. Based on the results of this survey and a detailed study of a specific service, we have built a generic model. The generic nature of the model relies on a common structure with a high level of detail. This model can be used to improve the performance of a specific sterilization service and/or to dimension its resources. It can also serve for quantitative comparison of performance indicators of various sterilization services.",2013-03,26/11/2018 12:52,14/04/2020 08:34,,45-61,,1,16,,Health Care Manag Sci,,,,,,,,eng,,,,,,,PMID: 22886097,,,,"France; Humans; Health Services Research; *Quality Improvement; *Models, Organizational; Efficiency, Organizational; 00; *Equipment and Supplies; Central Supply, Hospital/organization & administration; Sterilization/economics/*standards; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VVBFKXWJ,journalArticle,2013,"Zendejas, Benjamin; Wang, Amy T.; Brydges, Ryan; Hamstra, Stanley J.; Cook, David A.",Cost: the missing outcome in simulation-based medical education research: a systematic review.,Surgery,,1532-7361 0039-6060,10.1016/j.surg.2012.06.025,,"BACKGROUND: The costs involved with technology-enhanced simulation remain unknown. Appraising the value of simulation-based medical education (SBME) requires complete accounting and reporting of cost. We sought to summarize the quantity and quality of studies that contain an economic analysis of SBME for the training of health professions learners. METHODS: We performed a systematic search of MEDLINE, EMBASE, CINAHL, ERIC, PsychINFO, Scopus, key journals, and previous review bibliographies through May 2011. Articles reporting original research in any language evaluating the cost of simulation, in comparison with nonstimulation instruction or another simulation intervention, for training practicing and student physicians, nurses, and other health professionals were selected. Reviewers working in duplicate evaluated study quality and abstracted information on learners, instructional design, cost elements, and outcomes. RESULTS: From a pool of 10,903 articles we identified 967 comparative studies. Of these, 59 studies (6.1%) reported any cost elements and 15 (1.6%) provided information on cost compared with another instructional approach. We identified 11 cost components reported, most often the cost of the simulator (n = 42 studies; 71%) and training materials (n = 21; 36%). Ten potential cost components were never reported. The median number of cost components reported per study was 2 (range, 1-9). Only 12 studies (20%) reported cost in the Results section; most reported it in the Discussion (n = 34; 58%). CONCLUSION: Cost reporting in SBME research is infrequent and incomplete. We propose a comprehensive model for accounting and reporting costs in SBME.",2013-02,26/11/2018 12:52,14/04/2020 08:35,,160-176,,2,153,,Surgery,,,,,,,,eng,"Copyright (c) 2013 Mosby, Inc. All rights reserved.",,,,,,PMID: 22884087,,,,"Humans; Cost-Benefit Analysis; Computer Simulation/*economics; Models, Economic; 00; Education, Medical/*economics; Research/*economics; Teaching/economics; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 78ZI6DWQ,journalArticle,2012,"Qayumi, Karim; Donn, Stuart; Zheng, Bin; Young, Lynne; Dutton, James; Adamack, Monica; Bowles, Ron; Cheng, Adam",British Columbia interprofessional model for simulation-based education in health care: a network of simulation sites.,Simulation in healthcare : journal of the Society for Simulation in Healthcare,,1559-713X 1559-2332,10.1097/SIH.0b013e31825e8daa,,"The rapid uptake of simulation-based education has led to the development of simulation programs and centers all around the world. Unfortunately, many of these centers are functioning as localized silos and not taking advantage of the potential for collaboration with other regional centers to promote interprofessional education. In the province of British Columbia (BC), Canada, 38 institutions, including health care authorities, universities, colleges, and other health-related organizations, have participated in assessing the use of simulation in BC and in developing a provincial model that enables collaboration and interprofessional learning at the provincial level.This article describes methods and results of a needs assessment and discusses an interprofessional simulation in health care educational model that provides access for all health care professionals in BC regardless of their geographic location and/or institutional affiliation. We anticipate that this information will be useful to and supportive of others in developing simulation collaborations in their respective regions.",2012-10,26/11/2018 12:52,14/04/2020 08:35,,295-307,,5,7,,Simul Healthc,,,,,,,,eng,,,,,,,PMID: 22878583,,,,"Humans; *Models, Organizational; Health Personnel/*education; *Cooperative Behavior; *Interdisciplinary Communication; British Columbia; 00; Advisory Committees; Program Development/methods; Computer Simulation/*supply & distribution/utilization; Needs Assessment/*organization & administration; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 79LPR2PV,journalArticle,2012,"Guldbrandsson, Karin; Nordvik, Monica K.; Bremberg, Sven",Identification of potential opinion leaders in child health promotion in Sweden using network analysis.,BMC research notes,,1756-0500 1756-0500,10.1186/1756-0500-5-424,,"BACKGROUND: Opinion leaders are often local individuals with high credibility who can influence other people. Robust effects using opinion leaders in diffusing innovations have been shown in several randomized controlled trials, for example regarding sexually transmitted infections (STI), human immunodeficiency virus (HIV) prevention, mammography rates and caesarean birth delivery rates. In a Cochrane review 2010 it was concluded that the use of opinion leaders can successfully promote evidence-based practice. Thus, using opinion leaders within the public health sector might be one means to speed up the dissemination of health promoting and disease preventing innovations. Social network analysis has been used to trace and map networks, with focus on relationships and positions, in widely spread arenas and topics. The purpose of this study was to use social network analysis in order to identify potential opinion leaders at the arena of child health promotion in Sweden. RESULTS: By using snowball technique a short e-mail question was spread in up to five links, starting from seven initially invited persons. This inquiry resulted in a network consisting of 153 individuals. The most often mentioned actors were researchers, public health officials and paediatricians, or a combination of these professions. Four single individuals were mentioned by five to seven other persons in the network. These individuals obviously possess qualities that make other professionals within the public health sector listen to and trust them. CONCLUSIONS: Social network analysis seemed to be a useful method to identify influential persons with high credibility, i.e. potential opinion leaders, at the arena of child health promotion in Sweden. If genuine opinion leaders could be identified directed measures can be carried out in order to spread new and relevant knowledge. This may facilitate for public health actors at the local, regional and national level to more rapidly progress innovations into everyday practice. However, effectiveness studies of opinion leaders in the public health sector still have to be performed.",08/08/2012,26/11/2018 12:52,14/04/2020 08:34,,424,,,5,,BMC Res Notes,,,,,,,,eng,,,,,,,PMID: 22873749 PMCID: PMC3434052,,,,"Humans; Child; *Social Networking; Sweden; Feasibility Studies; *Health Knowledge, Attitudes, Practice; *Leadership; Interpersonal Relations; *Health Promotion; Trust; Interinstitutional Relations; Research Personnel; Administrative Personnel; *Public Opinion; *Information Dissemination; *Child Welfare; Pediatrics/manpower; Public Health/manpower; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LMG2VXC7,journalArticle,2012,"Ushida, Yasunori; Kato, Ryuji; Niwa, Kosuke; Tanimura, Daisuke; Izawa, Hideo; Yasui, Kenji; Takase, Tomokazu; Yoshida, Yasuko; Kawase, Mitsuo; Yoshida, Tsutomu; Murohara, Toyoaki; Honda, Hiroyuki",Combinational risk factors of metabolic syndrome identified by fuzzy neural network analysis of health-check data.,BMC medical informatics and decision making,,1472-6947 1472-6947,10.1186/1472-6947-12-80,,"BACKGROUND: Lifestyle-related diseases represented by metabolic syndrome develop as results of complex interaction. By using health check-up data from two large studies collected during a long-term follow-up, we searched for risk factors associated with the development of metabolic syndrome. METHODS: In our original study, we selected 77 case subjects who developed metabolic syndrome during the follow-up and 152 healthy control subjects who were free of lifestyle-related risk components from among 1803 Japanese male employees. In a replication study, we selected 2196 case subjects and 2196 healthy control subjects from among 31343 other Japanese male employees. By means of a bioinformatics approach using a fuzzy neural network (FNN), we searched any significant combinations that are associated with MetS. To ensure that the risk combination selected by FNN analysis was statistically reliable, we performed logistic regression analysis including adjustment. RESULTS: We selected a combination of an elevated level of gamma-glutamyltranspeptidase (gamma-GTP) and an elevated white blood cell (WBC) count as the most significant combination of risk factors for the development of metabolic syndrome. The FNN also identified the same tendency in a replication study. The clinical characteristics of gamma-GTP level and WBC count were statistically significant even after adjustment, confirming that the results obtained from the fuzzy neural network are reasonable. Correlation ratio showed that an elevated level of gamma-GTP is associated with habitual drinking of alcohol and a high WBC count is associated with habitual smoking. CONCLUSIONS: This result obtained by fuzzy neural network analysis of health check-up data from large long-term studies can be useful in providing a personalized novel diagnostic and therapeutic method involving the gamma-GTP level and the WBC count.",01/08/2012,26/11/2018 12:52,14/04/2020 08:35,,80,,,12,,BMC Med Inform Decis Mak,,,,,,,,eng,,,,,,,PMID: 22853735 PMCID: PMC3469424,,,,"Humans; Surveys and Questionnaires; Outcome and Process Assessment (Health Care); Adult; Male; Reproducibility of Results; Risk Factors; Follow-Up Studies; Risk Assessment; Logistic Models; Japan; *Life Style; Body Mass Index; Employment; 00; Environmental Exposure; *Fuzzy Logic; *Neural Networks (Computer); Computational Biology/*methods/standards; Diagnostic Tests, Routine; gamma-Glutamyltransferase/blood/metabolism; Leukocyte Count; Metabolic Syndrome/blood/*diagnosis; Specimen Handling; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RT5BXHFB,journalArticle,2013,"Bleibler, F.; Konnopka, A.; Benzinger, P.; Rapp, K.; Konig, H.-H.",The health burden and costs of incident fractures attributable to osteoporosis from 2010 to 2050 in Germany--a demographic simulation model.,Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA,,1433-2965 0937-941X,10.1007/s00198-012-2020-z,,"UNLABELLED: To predict the burden of incident osteoporosis attributable fractures (OAF) in Germany, an economic simulation model was built. The burden of OAF will sharply increase until 2050. Future demand for hospital and long-term care can be expected to substantially rise and should be considered in future healthcare planning. INTRODUCTION: The aim of this study was to develop an innovative simulation model to predict the burden of incident OAF occurring in the German population, aged >50, in the time period of 2010 to 2050. METHODS: A Markov state transition model based on five fracture states was developed to estimate costs and loss of quality adjusted life years (QALYs). Demographic change was modelled using individual generation life tables. Direct (inpatient, outpatient, long-term care) and indirect fracture costs attributable to osteoporosis were estimated by comparing Markov cohorts with and without osteoporosis. RESULTS: The number of OAF will rise from 115,248 in 2010 to 273,794 in 2050, cumulating to approximately 8.1 million fractures (78 % women, 22 % men) during the period between 2010 and 2050. Total undiscounted incident OAF costs will increase from around 1.0 billion Euros in 2010 to 6.1 billion Euros in 2050. Discounted (3 %) cumulated costs from 2010 to 2050 will amount to 88.5 billion Euros (168.5 undiscounted), with 76 % being direct and 24 % indirect costs. The discounted (undiscounted) cumulated loss of QALYs will amount to 2.5 (4.9) million. CONCLUSIONS: We found that incident OAF costs will sharply increase until the year 2050. As a consequence, a growing demand for long-term care as well as hospital care can be expected and should be considered in future healthcare planning. To support decision makers in managing the future burden of OAF, our model allows to economically evaluate population- and risk group-based interventions for fracture prevention in Germany.",2013-03,26/11/2018 12:52,14/04/2020 08:34,,835-847,,3,24,,Osteoporos Int,,,,,,,,eng,,,,,,,PMID: 22797490,,,,"Humans; Quality-Adjusted Life Years; Female; Male; Middle Aged; Aged; Markov Chains; Aged, 80 and over; Cost of Illness; *Models, Econometric; Health Services Research/methods; 1; Germany/epidemiology; Health Care Costs/statistics & numerical data/*trends; Health Planning/methods/trends; Hip Fractures/economics/epidemiology; Osteoporotic Fractures/*economics/epidemiology; Sex Distribution; Markov; 220",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PQS2U9WL,journalArticle,2012,"Diaz, Rafael; Behr, Joshua G.; Tulpule, Mandar",A system dynamics model for simulating ambulatory health care demands.,Simulation in healthcare : journal of the Society for Simulation in Healthcare,,1559-713X 1559-2332,10.1097/SIH.0b013e318259d134,,INTRODUCTION: This article demonstrates the utility of the system dynamics approach to model and simulate U.S. demand for ambulatory health care service both for the general population and for specific cohort subpopulations over the,2012-08,26/11/2018 12:52,14/04/2020 08:34,,243-250,,4,7,,Simul Healthc,,,,,,,,eng,,,,,,,PMID: 22722706,,,,"Humans; Adult; Female; Male; Middle Aged; Young Adult; Cohort Studies; Adolescent; *Models, Theoretical; Regression Analysis; *Systems Theory; 00; *Health Services Needs and Demand; Ambulatory Care/statistics & numerical data/*utilization; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WMI9YHZJ,journalArticle,2012,"Mager, Diana R.; Lange, Jean W.; Greiner, Philip A.; Saracino, Katherine H.",Using simulation pedagogy to enhance teamwork and communication in the care of older adults: the ELDER project.,Journal of continuing education in nursing,,0022-0124 0022-0124,10.3928/00220124-20120615-52,,The Expanded Learning and Dedication to Elders in the Region (ELDER) project addressed the needs of under-served older adults by educating health care providers in home health and long-term care facilities. Four agencies in a health professional shortage/medically underserved area participated. Focus groups were held to determine agency-specific educational needs. Curricula from the John A. Hartford Foundation were adapted to design unique curricula for each agency and level of personnel during the first 2 years. The focus of this report is the case-based simulation learning approach used in year 3 to validate application of knowledge and facilitate teamwork and interprofessional communication. Three simulation sessions on varying topics were conducted at each site. Postsimulation surveys and qualitative interviews with hired evaluators showed that participants found simulations helpful to their practice. Tailored on-site education incorporating mid-fidelity simulation was an effective model for translating gerontological knowledge into practice and encouraging communication and teamwork in these settings.,2012-08,26/11/2018 12:52,14/04/2020 08:34,,363-369,,8,43,,J Contin Educ Nurs,,,,,,,,eng,"Copyright 2012, SLACK Incorporated.",,,,,,PMID: 22715874,,,,"Humans; Adult; Middle Aged; Interprofessional Relations; Aged; Aged, 80 and over; Communication; Staff Development/*methods; 00; Education, Nursing, Continuing/*methods; Geriatric Nursing/*methods; Nursing, Team/*methods; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8A3XEUS9,journalArticle,2012,"Ammenwerth, Elske; Hackl, Werner O.; Binzer, Kristine; Christoffersen, Tue E. H.; Jensen, Sanne; Lawton, Kitta; Skjoet, Peter; Nohr, Christian",Simulation studies for the evaluation of health information technologies: experiences and results.,Health information management : journal of the Health Information Management Association of Australia,,1833-3575 1833-3583,,,"It is essential for new health information technologies (IT) to undergo rigorous evaluations to ensure they are effective and safe for use in real-world situations. However, evaluation of new health IT is challenging, as field studies are often not feasible when the technology being evaluated is not sufficiently mature. Laboratory-based evaluations have also been shown to have insufficient external validity. Simulation studies seem to be a way to bridge this gap. The aim of this study was to evaluate, using a simulation methodology, the impact of a new prototype of an electronic medication management system on the appropriateness of prescriptions and drug-related activities, including laboratory test ordering or medication changes. This article presents the results of a controlled simulation study with 50 simulation runs, including ten doctors and five simulation patients, and discusses experiences and lessons learnt while conducting the study. Although the new electronic medication management system showed tendencies to improve medication safety when compared with the standard system, this tendency was not significant. Altogether, five distinct situations were identified where the new medication management system did help to improve medication safety. This simulation study provided a good compromise between internal validity and external validity. However, several challenges need to be addressed when undertaking simulation evaluations including: preparation of adequate test cases; training of participants before using unfamiliar applications; consideration of time, effort and costs of conducting the simulation; technical maturity of the evaluated system; and allowing adequate preparation of simulation scenarios and simulation setting. Simulation studies are an interesting but time-consuming approach, which can be used to evaluate newly developed health IT systems, particularly those systems that are not yet sufficiently mature to undergo field evaluation studies.",2012,26/11/2018 12:52,14/04/2020 08:34,,14-21,,2,41,,Health Inf Manag,,,,,,,,eng,,,,,,,PMID: 22700558,,,,"Humans; *Patient Simulation; Medication Errors/*prevention & control; Attitude of Health Personnel; Denmark; 1; Decision Making, Computer-Assisted; Medical Informatics/methods/*standards/trends; Medical Order Entry Systems/*organization & administration/standards; Technology Assessment, Biomedical/*methods/standards; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PVN8GXXM,journalArticle,2012,"Walsh, Catharine M.; Sherlock, Mary E.; Ling, Simon C.; Carnahan, Heather",Virtual reality simulation training for health professions trainees in gastrointestinal endoscopy.,The Cochrane database of systematic reviews,,1469-493X 1361-6137,10.1002/14651858.CD008237.pub2,,"BACKGROUND: Traditionally, training in gastrointestinal endoscopy has been based upon an apprenticeship model, with novice endoscopists learning basic skills under the supervision of experienced preceptors in the clinical setting. Over the last two decades, however, the growing awareness of the need for patient safety has brought the issue of simulation-based training to the forefront. While the use of simulation-based training may have important educational and societal advantages, the effectiveness of virtual reality gastrointestinal endoscopy simulators has yet to be clearly demonstrated. OBJECTIVES: To determine whether virtual reality simulation training can supplement and/or replace early conventional endoscopy training (apprenticeship model) in diagnostic oesophagogastroduodenoscopy, colonoscopy and/or sigmoidoscopy for health professions trainees with limited or no prior endoscopic experience. SEARCH METHODS: Health professions, educational and computer databases were searched until November 2011 including The Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE, Scopus, Web of Science, Biosis Previews, CINAHL, Allied and Complementary Medicine Database, ERIC, Education Full Text, CBCA Education, Career and Technical Education @ Scholars Portal, Education Abstracts @ Scholars Portal, Expanded Academic ASAP @ Scholars Portal, ACM Digital Library, IEEE Xplore, Abstracts in New Technologies and Engineering and Computer & Information Systems Abstracts. The grey literature until November 2011 was also searched. SELECTION CRITERIA: Randomised and quasi-randomised clinical trials comparing virtual reality endoscopy (oesophagogastroduodenoscopy, colonoscopy and sigmoidoscopy) simulation training versus any other method of endoscopy training including conventional patient-based training, in-job training, training using another form of endoscopy simulation (e.g. low-fidelity simulator), or no training (however defined by authors) were included. Trials comparing one method of virtual reality training versus another method of virtual reality training (e.g. comparison of two different virtual reality simulators) were also included. Only trials measuring outcomes on humans in the clinical setting (as opposed to animals or simulators) were included. DATA COLLECTION AND ANALYSIS: Two authors (CMS, MES) independently assessed the eligibility and methodological quality of trials, and extracted data on the trial characteristics and outcomes. Due to significant clinical and methodological heterogeneity it was not possible to pool study data in order to perform a meta-analysis. Where data were available for each continuous outcome we calculated standardized mean difference with 95% confidence intervals based on intention-to-treat analysis. Where data were available for dichotomous outcomes we calculated relative risk with 95% confidence intervals based on intention-to-treat-analysis. MAIN RESULTS: Thirteen trials, with 278 participants, met the inclusion criteria. Four trials compared simulation-based training with conventional patient-based endoscopy training (apprenticeship model) whereas nine trials compared simulation-based training with no training. Only three trials were at low risk of bias. Simulation-based training, as compared with no training, generally appears to provide participants with some advantage over their untrained peers as measured by composite score of competency, independent procedure completion, performance time, independent insertion depth, overall rating of performance or competency error rate and mucosal visualization. Alternatively, there was no conclusive evidence that simulation-based training was superior to conventional patient-based training, although data were limited. AUTHORS' CONCLUSIONS: The results of this systematic review indicate that virtual reality endoscopy training can be used to effectively supplement early conventional endoscopy training (apprenticeship model) in diagnostic oesophagogastroduodenoscopy, colonoscopy and/or sigmoidoscopy for health professions trainees with limited or no prior endoscopic experience. However, there remains insufficient evidence to advise for or against the use of virtual reality simulation-based training as a replacement for early conventional endoscopy training (apprenticeship model) for health professions trainees with limited or no prior endoscopic experience. There is a great need for the development of a reliable and valid measure of endoscopic performance prior to the completion of further randomised clinical trials with high methodological quality.",13/06/2012,26/11/2018 12:52,14/04/2020 08:35,,CD008237,,6,,,Cochrane Database Syst Rev,,,,,,,,eng,,,,,,,PMID: 22696375,,,,"Humans; Randomized Controlled Trials as Topic; *Computer Simulation; 00; Health Occupations/*education; Endoscopy, Gastrointestinal/*education; 110; 1110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5X4LL48D,journalArticle,2012,"Kidd, Lori I.; Knisley, Samantha J.; Morgan, Karyn I.",Effectiveness of a second life((R)) simulation as a teaching strategy for undergraduate mental health nursing students.,Journal of psychosocial nursing and mental health services,,0279-3695 0279-3695,10.3928/02793695-20120605-04,,"Learning may be enhanced in mental health nursing education by applying virtual reality technologies in which students may safely practice communication and assessment skills with simulated patients. The purpose of this descriptive study was to assess the effectiveness of a Second Life((R)) (SL) virtual simulation as a teaching strategy for undergraduate mental health nursing students. Data were collected via a researcher-developed survey questionnaire. Students perceived the simulation to be moderately effective as an educational strategy and slightly difficult as a technical program. Positive aspects included client assessment in an environment where mistakes were without consequence, working from home, and novelty. Drawbacks were dressing and maneuvering the avatar and lack of realism. Correlations were found between educational effectiveness and technical difficulty and between educational effectiveness and age of the computer. SL virtual simulation has potential to provide unique, easily accessible, safe, and fun learning for mental health nursing students.",2012-07,26/11/2018 12:52,14/04/2020 08:34,,28-37,,7,50,,J Psychosoc Nurs Ment Health Serv,,,,,,,,eng,"Copyright 2012, SLACK Incorporated.",,,,,,PMID: 22694785,,,,"Humans; United States; Female; Male; Curriculum; *Computer Simulation; Education, Nursing, Baccalaureate; Psychiatric Nursing/*education; Attitude of Health Personnel; *User-Computer Interface; *Nurse-Patient Relations; 00; Education, Nursing, Graduate; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4KYCSRTX,journalArticle,2012,"Fuller, Jeffrey; Hermeston, Wendy; Passey, Megan; Fallon, Tony; Muyambi, Kuda",Acceptability of participatory social network analysis for problem-solving in Australian Aboriginal health service partnerships.,BMC health services research,,1472-6963 1472-6963,10.1186/1472-6963-12-152,,"BACKGROUND: While participatory social network analysis can help health service partnerships to solve problems, little is known about its acceptability in cross-cultural settings. We conducted two case studies of chronic illness service partnerships in 2007 and 2008 to determine whether participatory research incorporating social network analysis is acceptable for problem-solving in Australian Aboriginal health service delivery. METHODS: Local research groups comprising 13-19 partnership staff, policy officers and community members were established at each of two sites to guide the research and to reflect and act on the findings. Network and work practice surveys were conducted with 42 staff, and the results were fed back to the research groups. At the end of the project, 19 informants at the two sites were interviewed, and the researchers conducted critical reflection. The effectiveness and acceptability of the participatory social network method were determined quantitatively and qualitatively. RESULTS: Participants in both local research groups considered that the network survey had accurately described the links between workers related to the exchange of clinical and cultural information, team care relationships, involvement in service management and planning and involvement in policy development. This revealed the function of the teams and the roles of workers in each partnership. Aboriginal workers had a high number of direct links in the exchange of cultural information, illustrating their role as the cultural resource, whereas they had fewer direct links with other network members on clinical information exchange and team care. The problem of their current and future roles was discussed inside and outside the local research groups. According to the interview informants the participatory network analysis had opened the way for problem-solving by ""putting issues on the table"". While there were confronting and ethically challenging aspects, these informants considered that with flexibility of data collection to account for the preferences of Aboriginal members, then the method was appropriate in cross-cultural contexts for the difficult discussions that are needed to improve partnerships. CONCLUSION: Critical reflection showed that the preconditions for difficult discussions are, first, that partners have the capacity to engage in such discussions, second, that partners assess whether the effort required for these discussions is balanced by the benefits they gain from the partnership, and, third, that ""boundary spanning"" staff can facilitate commitment to partnership goals.",10/06/2012,26/11/2018 12:52,14/04/2020 08:34,,152,,,12,,BMC Health Serv Res,,,,,,,,eng,,,,,,,PMID: 22682504 PMCID: PMC3472193,,,,"Humans; Surveys and Questionnaires; Organizational Case Studies; Australia; *Social Networking; *Community-Based Participatory Research; Capacity Building; *Problem Solving; 00; Cross-Cultural Comparison; Health Services, Indigenous; Oceanic Ancestry Group; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ZDAVCA7S,journalArticle,2012,"Nguyen, Christine M.; Bounthavong, Mark; Mendes, Margaret A. S.; Christopher, Melissa L. D.; Tran, Josephine N.; Kazerooni, Rashid; Morreale, Anthony P.",Cost utility of tumour necrosis factor-alpha inhibitors for rheumatoid arthritis: an application of Bayesian methods for evidence synthesis in a Markov model.,PharmacoEconomics,,1179-2027 1170-7690,10.2165/11594990-000000000-00000,,"BACKGROUND: Rheumatoid arthritis (RA) is a chronic autoimmune disease that affects approximately 1.5 million people in the US. Tumour necrosis factor (TNF)-alpha inhibitors have been shown to effectively treat and maintain remission in patients with moderately to severely active RA compared with conventional agents. The high acquisition cost of TNF-alpha inhibitors prohibits access, which mandates economic investigations into their affordability. The lack of head-to-head comparisons between these agents makes it difficult to determine which agent is the most cost effective. OBJECTIVE: This study aimed to determine which TNF-alpha inhibitor was the most cost-effective agent for the treatment of moderately to severely active RA from the US healthcare payer's perspective. METHODS: A Markov model was constructed to analyse the cost utility of five",01/07/2012,26/11/2018 12:52,14/04/2020 08:35,,575-593,,7,30,,Pharmacoeconomics,,,,,,,,eng,,,,,,,PMID: 22640174,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Markov Chains; Bayes Theorem; Models, Economic; Etanercept; Methotrexate/economics/therapeutic use; Receptors, Tumor Necrosis Factor/therapeutic use; Tumor Necrosis Factor-alpha/*antagonists & inhibitors; Drug Therapy, Combination; 00; Arthritis, Rheumatoid/*drug therapy/*economics; Health Resources/economics/utilization; Immunoglobulin G/therapeutic use; Immunosuppressive Agents/economics/therapeutic use; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NTVTXRUY,journalArticle,2012,"Storr, Julie; Kilpatrick, Claire",Hand hygiene improvement in the community: a systems approach.,British journal of community nursing,,1462-4753 1462-4753,,,"Hand hygiene compliance, which is influenced in part by human behaviour, is central to infection prevention in all care settings. This article focuses specifically on the importance of a multimodal strategy for continued hand hygiene improvement, and its relevance to community nursing. Additionally, the article addresses the challenges and opportunities of infection prevention and control in a community context, and highlights current national and international guidelines that offer a framework and set of principles for implementation and sustainability with a specific focus on the multimodal strategy associated with the WHO Guidelines on Hand Hygiene in Health Care (2009). The authors conclude with some considerations for community nurses when addressing translation of these principles into their everyday working context.",2012-03,26/11/2018 12:52,14/04/2020 08:35,,"S24-6, S28-29",,,Suppl,,Br J Community Nurs,,,,,,,,eng,,,,,,,PMID: 22584181,,,,Humans; *Health Personnel; Inservice Training; 00; Safety Management; *Hygiene; Guideline Adherence; Cross Infection/*prevention & control/transmission; Hand Disinfection/methods/*standards; Infection Control/*standards; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FCGJ6WI5,journalArticle,2012,"Gaebler, Julia A.; Soto-Campos, Gerardo; Alperin, Peter; Cohen, Marc; Blickensderfer, Amy; Wintle, Matthew; Maggs, David; Hoogwerf, Byron; Han, Jenny; Pencek, Richard; Peskin, Barbara","Health and economic outcomes for exenatide once weekly, insulin, and pioglitazone therapies in the treatment of type 2 diabetes: a simulation analysis.",Vascular health and risk management,,1178-2048 1176-6344,10.2147/VHRM.S28744,,"BACKGROUND: Patients with type 2 diabetes (T2DM) are at risk of long-term vascular complications. In trials, exenatide once weekly (ExQW), a GLP-1R agonist, improved glycemia, weight, blood pressure (BP), and lipids in patients with T2DM. We simulated potential effects of ExQW on vascular complications, survival, and medical costs over 20 years versus standard therapies. PATIENTS AND METHODS: The Archimedes model was used to assess outcomes for ~25,000 virtual patients with T2DM (NHANES 1999-2006 [metformin +/- sulfonylureas, age 57 years, body mass index 33 kg/m(2), weight 94 kg, duration T2DM 9 years, hemoglobin A1c [A1C] 8.1%]). The effects of three treatment strategies were modeled and compared to moderate-adherence insulin therapy: advancement to high-adherence insulin at A1C >/= 8% (treat to target A1C < 7%) and addition of pioglitazone (PIO) or ExQW from simulation start. ExQW effects on A1C, weight, BP, and lipids were modeled from clinical trial data. Costs, inflated to represent 2010 $US, were derived from Medicare data, Drugstore.com, and publications. As ExQW was investigational, we omitted ExQW, PIO, and insulin pharmacy costs. RESULTS: By year 1, ExQW treatment decreased A1C (~1.5%), weight (~2 kg), and systolic BP (~5 mmHg). PIO and high-adherence insulin decreased A1C by ~1%, increased weight, and did not affect systolic BP. After 20 years, A1C was ~7% with all strategies. ExQW decreased rates of cardiovascular and microvascular complications more than PIO or high-adherence insulin versus moderate-adherence insulin. Over 20 years, ExQW treatment resulted in increased quality-adjusted life-years (QALYs) of ~0.3 years/person and cost savings of $469/life-year versus moderate adherence insulin. For PIO or high-adherence insulin, QALYs were virtually unchanged, and costs/life-year versus moderate-adherence insulin increased by $69 and $87, respectively. CONCLUSIONS: This long-term simulation demonstrated that ExQW treatment may decrease rates of cardiovascular and some microvascular complications of T2DM. Increased QALYs, and decreased costs were also projected.",2012,26/11/2018 12:52,14/04/2020 08:34,,255-264,,,8,,Vasc Health Risk Manag,,,,,,,,eng,,,,,,,PMID: 22566747 PMCID: PMC3346268,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Treatment Outcome; Female; Male; Middle Aged; Risk Factors; Aged; Risk Assessment; *Computer Simulation; Nutrition Surveys; Medication Adherence; United States/epidemiology; Time Factors; Models, Economic; Drug Administration Schedule; *Drug Costs; Outcome and Process Assessment (Health Care)/*economics; diabetes; 00; Biomarkers/blood; Blood Glucose/drug effects/metabolism; cardiovascular risk; Diabetes Mellitus, Type 2/blood/complications/*drug therapy/*economics/mortality; Diabetic Angiopathies/economics/mortality/prevention & control; exenatide; Glycated Hemoglobin A/metabolism; Hypoglycemic Agents/administration & dosage/*economics; insulin; Insulin/administration & dosage/*economics; modeling; Peptides/administration & dosage/*economics; pioglitazone; Thiazolidinediones/administration & dosage/*economics; Venoms/administration & dosage/*economics; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, U66HTD62,journalArticle,2013,"Nicaise, Pablo; Tulloch, Simon; Dubois, Vincent; Matanov, Aleksandra; Priebe, Stefan; Lorant, Vincent",Using social network analysis for assessing mental health and social services inter-organisational collaboration: findings in deprived areas in Brussels and London.,Administration and policy in mental health,,1573-3289 0894-587X,10.1007/s10488-012-0423-y,,"Fragmentation in mental health and social care delivery should be addressed at the system level. A Social Network Analysis was carried out on relations between services in order to assess Leutz's levels of care integration: linkage, coordination, and full integration. Findings for deprived areas in Brussels and London show that linkage across clusters of services is weak in both networks. However, the integration of care relies on the level of linkage in London, while in Brussels it is more dependent on central services playing brokerage roles. The method offers a useful and complementary basis for evaluating the integration of care.",2013-07,26/11/2018 12:52,14/04/2020 08:35,,331-339,,4,40,,Adm Policy Ment Health,,,,,,,,eng,,,,,,,PMID: 22543978,,,,"Humans; Surveys and Questionnaires; *Social Networking; Models, Organizational; *Cooperative Behavior; 00; *Poverty Areas; Belgium; London; Mental Health Services/*organization & administration; Social Work/*organization & administration; Vulnerable Populations/psychology; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, F48JKBDL,journalArticle,2013,"Keeling, Jonathan W.; Pryde, Julie A.; Merrill, Jacqueline A.",The influence of management and environment on local health department organizational structure and adaptation: a longitudinal network analysis.,Journal of public health management and practice : JPHMP,,1550-5022 1078-4659,10.1097/PHH.0b013e3182544800,,"OBJECTIVE: The nation's 2862 local health departments (LHDs) are the primary means for assuring public health services for all populations. The objective of this study is to assess the effect of organizational network analysis on management decisions in LHDs and to demonstrate the technique's ability to detect organizational adaptation over time. DESIGN AND SETTING: We conducted a longitudinal network analysis in a full-service LHD with 113 employees serving about 187,000 persons. Network survey data were collected from employees at 3 times: months 0, 8, and 34. At time 1 the initial analysis was presented to LHD managers as an intervention with information on evidence-based management strategies to address the findings. At times 2 and 3 interviews documented managers' decision making and events in the task environment. RESULTS: Response rates for the 3 network analyses were 90%, 97%, and 83%. Postintervention (time 2) results showed beneficial changes in network measures of communication and integration. Screening and case identification increased for chlamydia and for gonorrhea. Outbreak mitigation was accelerated by cross-divisional teaming. Network measurements at time 3 showed LHD adaptation to H1N1 and budget constraints with increased centralization. Task redundancy increased dramatically after National Incident Management System training. CONCLUSIONS: Organizational network analysis supports LHD management with empirical evidence that can be translated into strategic decisions about communication, allocation of resources, and addressing knowledge gaps. Specific population health outcomes were traced directly to management decisions based on network evidence. The technique can help managers improve how LHDs function as organizations and contribute to our understanding of public health systems.",2013-12,26/11/2018 12:52,14/04/2020 08:34,,598-605,,6,19,,J Public Health Manag Pract,,,,,,,,eng,,,,,,,PMID: 22510786,,,,"Humans; Adult; Middle Aged; Young Adult; Aged; Qualitative Research; Adolescent; Quality Improvement; Longitudinal Studies; *Public Health Administration; Organizational Innovation; 00; *Decision Making, Organizational; Health Information Management; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, D9GYJRKB,journalArticle,2013,"Loyo, Heather Karina; Batcher, Cynthia; Wile, Kristina; Huang, Philip; Orenstein, Diane; Milstein, Bobby",From model to action: using a system dynamics model of chronic disease risks to align community action.,Health promotion practice,,1524-8399 1524-8399,10.1177/1524839910390305,,"Health planners in Austin, Texas, are using a System Dynamics Model of Cardiovascular Disease Risks (SD model) to align prevention efforts and maximize the effect of limited resources. The SD model was developed using available evidence of disease prevalence, risk factors, local contextual factors, resulting health conditions, and their impact on population health. Given an interest in understanding opportunities for upstream health protection, the SD model focused on the portion of the population that has never had a cardiovascular event. Leaders in Austin used this interactive simulation model as a catalyst for convening diverse stakeholders in thinking about their strategic directions and policy priorities. Health officials shared insights from the model with a range of organizations in an effort to align actions and leverage assets in the community to promote healthier conditions for all. This article summarizes the results from several simulated intervention scenarios focusing specifically on conditions in East Travis County, an area marked by higher prevalence of adverse living conditions and related chronic diseases. The article also describes the formation of a new Chronic Disease Prevention Coalition in Austin, along with shifts in its members' perceived priorities for intervention both before and after interactions with the SD model.",2013-01,26/11/2018 12:52,14/04/2020 08:34,,53-61,,1,14,,Health Promot Pract,,,,,,,,eng,,,,,,,PMID: 22491443,,,,"Humans; Health Policy; Risk Factors; Models, Theoretical; Texas; System dynamics; Chronic Disease/prevention & control; Health Planning; Cardiovascular Diseases/*etiology/prevention & control; Community Health Services/organization & administration; Community Participation; Health Priorities; 1; 320",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TJ8T25ZL,journalArticle,2012,"BeLue, Rhonda; Carmack, Chakema; Myers, Kyle R.; Weinreb-Welch, Laurie; Lengerich, Eugene J.",Systems thinking tools as applied to community-based participatory research: a case study.,Health education & behavior : the official publication of the Society for Public Health Education,,1552-6127 1090-1981,10.1177/1090198111430708,,"Community-based participatory research (CBPR) is being used increasingly to address health disparities and complex health issues. The authors propose that CBPR can benefit from a systems science framework to represent the complex and dynamic characteristics of a community and identify intervention points and potential ""tipping points."" Systems science refers to a field of study that posits a holistic framework that is focused on component parts of a system in the context of relationships with each other and with other systems. Systems thinking tools can assist in intervention planning by allowing all CBPR stakeholders to visualize how community factors are interrelated and by potentially identifying the most salient intervention points. To demonstrate the potential utility of systems science tools in CBPR, the authors show the use of causal loop diagrams by a community coalition engaged in CBPR activities regarding youth drinking reduction and prevention.",2012-12,26/11/2018 12:52,14/04/2020 08:34,,745-751,,6,39,,Health Educ Behav,,,,,,,,eng,,,,,,,PMID: 22467637,,,,Humans; Environment; Adolescent; *Systems Theory; Residence Characteristics; Adolescent Behavior; 00; Social Environment; Alcoholism/epidemiology; Community-Based Participatory Research/*methods; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9LMY6SCR,journalArticle,2012,"Kegler, Alissa L.; Dale, Brandy D.; McCarthy, Amy J.",The use of high-fidelity simulation for rapid response team training: a community hospital's story.,Journal for nurses in staff development : JNSD : official journal of the National Nursing Staff Development Organization,,1538-9049 1098-7886,10.1097/NND.0b013e31824b412a,,"The authors describe how simulation training was used to improve rapid response team activation in a nonteaching, nonprofit community hospital. Goals were established, and a scenario was developed to educate the healthcare team on the importance of early activation of the rapid response ream. Organizing and implementing a large-scale simulation required a solid commitment from the staff development department. The education from the simulation has led to increased knowledge and comfort levels of clinical staff, resulting in an increased use of the rapid response team.",2012-04,26/11/2018 12:52,14/04/2020 08:34,,50-52,,2,28,,J Nurses Staff Dev,,,,,,,,eng,,,,,,,PMID: 22449875,,,,"Humans; Quality of Health Care; Learning; Communication; *Clinical Competence; Educational Status; Time Factors; Models, Educational; Teaching/*methods; 00; Education, Nursing, Continuing/*methods; Colorado; Hospital Rapid Response Team/*organization & administration/standards; Hospitals, Community/*standards; Methicillin-Resistant Staphylococcus aureus; Patient Care/*methods/standards; Safety/*standards; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VQ5MN98V,journalArticle,2012,"Huntington, Dale; Banzon, Eduardo; Recidoro, Zenaida Dy",A systems approach to improving maternal health in the Philippines.,Bulletin of the World Health Organization,,1564-0604 0042-9686,10.2471/BLT.11.092825,,"OBJECTIVE: To examine the impact of health-system-wide improvements on maternal health outcomes in the Philippines. METHODS: A retrospective longitudinal controlled study was used to compare a province that fast tracked the implementation of health system reforms with other provinces in the same region that introduced reforms less systematically and intensively between 2006 and 2009. FINDINGS: The early reform province quickly upgraded facilities in the tertiary and first level referral hospitals; other provinces had just begun reforms by the end of the study period. The early reform province had created 871 women's health teams by the end of 2009, compared with 391 teams in the only other province that reported such teams. The amount of maternal-health-care benefits paid by the Philippine Health Insurance Corporation in the early reform province grew by approximately 45%; in the other provinces, the next largest increase was 16%. The facility-based delivery rate increased by 44 percentage points in the early reform province, compared with 9-24 percentage points in the other provinces. Between 2006 and 2009, the actual number of maternal deaths in the early reform province fell from 42 to 18, and the maternal mortality ratio from 254 to 114. Smaller declines in maternal deaths over this period were seen in Camarines Norte (from 12 to 11) and Camarines Sur (from 26- to 23). The remaining three provinces reported increases in maternal deaths. CONCLUSION: Making health-system-wide reforms to improve maternal health has positive synergistic effects.",01/02/2012,26/11/2018 12:52,14/04/2020 08:34,,104-110,,2,90,,Bull World Health Organ,,,,,,,,eng,,,,,,,PMID: 22423161 PMCID: PMC3302555,,,,Humans; Female; Retrospective Studies; Program Development; Pregnancy; Public Health; Prevalence; *Program Evaluation; *Systems Theory; Government Regulation; 00; *Maternal Welfare; Maternal Mortality; Philippines; Pregnancy Outcome/*epidemiology; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, T47KLHFY,journalArticle,2013,"Lamping, Antonie J.; Raab, Jorg; Kenis, Patrick",Participation and coordination in Dutch health care policy-making. A network analysis of the system of intermediate organizations in Dutch health care.,Health promotion international,,1460-2245 0957-4824,10.1093/heapro/das007,,"This study explores the system of intermediate organizations in Dutch health care as the crucial system to understand health care policy-making in the Netherlands. We argue that the Dutch health care system can be understood as a system consisting of distinct but inter-related policy domains. In this study, we analyze four such policy domains: Finances, quality of care, manpower planning and pharmaceuticals. With the help of network analytic techniques, we describe how this highly differentiated system of >200 intermediate organizations is structured and coordinated and what (policy) consequences can be observed with regard to its particular structure and coordination mechanisms. We further analyze the extent to which this system of intermediate organizations enables participation of stakeholders in policy-making using network visualization tools. The results indicate that coordination between the different policy domains within the health care sector takes place not as one would expect through governmental agencies, but through representative organizations such as the representative organizations of the (general) hospitals, the health care consumers and the employers' association. We further conclude that the system allows as well as denies a large number of potential participants access to the policy-making process. As a consequence, the representation of interests is not necessarily balanced, which in turn affects health care policy. We find that the interests of the Dutch health care consumers are well accommodated with the national umbrella organization NPCF in the lead. However, this is no safeguard for the overall community values of good health care since, for example, the interests of the public health sector are likely to be marginalized.",2013-06,26/11/2018 12:52,14/04/2020 08:34,,211-222,,2,28,,Health Promot Int,,,,,,,,eng,,,,,,,PMID: 22411896,,,,Humans; Health Policy; Netherlands; Surveys and Questionnaires; Quality of Health Care/organization & administration; *Policy Making; 1; network analysis; Delivery of Health Care/economics/manpower/methods/*organization & administration; Dutch health care; health care policy; Health Care Sector/organization & administration; Health Manpower/organization & administration; Health Planning/methods/organization & administration; Healthcare Financing; system of intermediate organizations; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5ZFVIZFX,journalArticle,2012,"Rudin, Robert S.; Schneider, Eric C.; Volk, Lynn A.; Szolovits, Peter; Salzberg, Claudia A.; Simon, Steven R.; Bates, David W.",Simulation Suggests that medical group mergers won't undermine the potential utility of health information exchanges.,Health affairs (Project Hope),,1544-5208 0278-2715,10.1377/hlthaff.2011.0799,,"Federal and state agencies are investing substantial resources in the creation of community health information exchanges, which are consortia that enable independent health care organizations to exchange clinical data. However, under pressure to form accountable care organizations, medical groups may merge and support private health information exchanges. Such activity could reduce the potential utility of community exchanges-that is, the exchanges' capacity to share patient data across hospitals and physician practices that are independent. Simulations of care transitions based on data from ten Massachusetts communities suggest that there would have to be many such mergers to undermine the potential utility of health information exchanges. At the same time, because hospitals and the largest medical groups account for only 10-20 percent of care transitions in a community, information exchanges will still need to recruit a large proportion of the medical groups in a given community for the exchanges to maintain their usefulness in fostering information exchange across independent providers.",2012-03,26/11/2018 12:52,14/04/2020 08:34,,548-559,,3,31,,Health Aff (Millwood),,,,,,,,eng,,,,,,,PMID: 22392665 PMCID: PMC3759523,,,,Humans; United States; Computer Simulation; Costs and Cost Analysis; 00; Information Dissemination/methods; *Medical Record Linkage; Accountable Care Organizations/*economics/trends; Group Practice/economics/*organization & administration/trends; Health Facility Merger/*economics/trends; Review,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XZU6WSDS,journalArticle,2013,"Mascia, Daniele; Di Vincenzo, Fausto",Dynamics of hospital competition: social network analysis in the Italian National Health Service.,Health care management review,,1550-5030 0361-6274,10.1097/HMR.0b013e31824ccab8,,"BACKGROUND: In the early 1990s, the governments of many countries took the first steps toward introducing market forces into the provision of health care services, with the aim of increasing hospital efficiency and quality of care. Several reforms have been developed to strengthen the role of competition, giving rise to forms of ""managed competition."" As a result, the environment in which providers operate and perform is increasingly characterized by conditions of competition, rather than of cooperation. PURPOSE: The aim of this study was to analyze the evolution of competitive interdependences among hospitals and the impact of organizational demographics on pair-wise competition. METHODOLOGY: Longitudinal data on competitive interdependences collected within a regional community of hospital organizations in the Italian National Health Service were analyzed. Stochastic actor-based models designed for estimating network dynamics were used to study organizational characteristics influencing patterns of change in competitive interdependences. FINDINGS: The results indicated that interorganizational cooperation is a significant predictor of competitive interdependences, that pair-wise competition among hospitals is primarily local, and that competitive interdependences are more likely to occur between local providers that differed with respect to performance and volume of activity. PRACTICE IMPLICATIONS: Exploring the evolution of competitive interdependences between hospitals is salient for administrators who are interested in increasing their understanding of the whole market. They can better identify direct competitors by paying particular attention to those organizational characteristics that likely predict competitive actions. This approach is also important for policy makers, which may be interested in better targeting hospital restructuring interventions while implementing procompetition reforms.",2013-09,26/11/2018 12:52,14/04/2020 08:34,,234-247,,3,38,,Health Care Manage Rev,,,,,,,,eng,,,,,,,PMID: 22387971,,,,Humans; Longitudinal Studies; Italy; Social Support; Organizational Innovation; Interinstitutional Relations; 00; National Health Programs/*economics; International Cooperation; *Economic Competition; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9SWFWRZU,journalArticle,2012,"Bearman, Margaret; O'Brien, Robert; Anthony, Adrian; Civil, Ian; Flanagan, Brendan; Jolly, Brian; Birks, David; Langcake, Mary; Molloy, Elizabeth; Nestel, Debra","Learning surgical communication, leadership and teamwork through simulation.",Journal of surgical education,,1878-7452 1878-7452,10.1016/j.jsurg.2011.07.014,,"BACKGROUND: In Australia and New Zealand, surgical trainees are expected to develop competencies across 9 domains. Although structured training is provided in several domains, there is little or no formal program for professionalism, communication, collaboration, and management and leadership. The Australian federal Department of Health and Aging funded a pilot course in simulation-based education to address these competencies for surgical trainees. This article describes the course and evaluation. METHODS: Course development: Content and methods drew on best-evidence for teaching and learning these competencies from other disciplines. Course evaluation: Participants completed surveys using rating scales and free text comments to identify aspects of the course that worked well and those that needed improvement. RESULTS: Eleven of 12 participants completed evaluation forms immediately after the course. Participants reported largely meeting learning objectives and valuing the educational methods. High levels of realism in simulations contributed to the ease with which participants immersed themselves in scenarios. CONCLUSIONS: This study demonstrates that a course designed to teach competencies in communication, teamwork, leadership, and the encompassing professionalism to surgical trainees is feasible. Although participants valued the content and methods, they identified areas for development. Limitations of the evaluation are highlighted, and further areas for research are identified.",2012-04,26/11/2018 12:52,14/04/2020 08:34,,201-207,,2,69,,J Surg Educ,,,,,,,,eng,Copyright A(c) 2012 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.,,,,,,PMID: 22365866,,,,"Humans; Program Evaluation; Adult; Female; Learning; Male; Young Adult; Patient Care Team/organization & administration; *Computer Simulation; *Clinical Competence; Pilot Projects; Australia; *Leadership; Cooperative Behavior; *Interdisciplinary Communication; Problem-Based Learning; 00; Internship and Residency/*organization & administration; Education, Medical, Graduate/methods; General Surgery/*education; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BCNK9GQH,journalArticle,2012,"Bandali, Karim S.; Craig, Robert; Ziv, Amitai","Innovations in applied health: evaluating a simulation-enhanced, interprofessional curriculum.",Medical teacher,,1466-187X 0142-159X,10.3109/0142159X.2012.642829,,"BACKGROUND: In response to current trends in healthcare education, teachers at the Michener Institute for Applied Health Sciences implemented a New Curriculum Model (NCM) in 2006, building a curriculum to better transition students from didactic to clinical education. Through the implementation of interprofessional education and simulated clinical scenarios, educators created a setting to develop, contextualize and apply students' skills before entry to the clinical environment. AIMS: In this pilot study, researchers assessed the impact of the NCM intervention on student preparedness for clinical practicum. METHODS: A mixed-methods evaluation was conducted, collecting survey assessments and qualitative focus group feedback from clinical educators and students. RESULTS: Clinical educators identified Michener NCM students to be significantly better prepared for clinical practicum when compared to previous cohorts (p < 0.05%). Students also noted significant improvements as implementation issues were resolved from years one to two of the NCM. CONCLUSIONS: The infusion of simulation and interprofessional education into Michener's applied health curricula resulted in a significant improvement in clinical preparedness. The Michener NCM bridged the gap previously separating didactic education and clinical practice, transitioning applied health students from trained technicians to more complete health care professionals.",2012,26/11/2018 12:52,14/04/2020 08:34,,e176-184,,3,34,,Med Teach,,,,,,,,eng,,,,,,,PMID: 22364474,,,,"Humans; Computer Simulation; Pilot Projects; Models, Educational; 1; Clinical Competence/*standards; Health Occupations/*education; *Students, Health Occupations; Curriculum/standards/trends; Interdisciplinary Studies/standards/*trends; Problem-Based Learning/*methods/standards/trends; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HBS52ZPL,journalArticle,2012,"Lorenzana, Sarah B.; Hughes, Michael D.; Grinsztejn, Beatriz; Collier, Ann C.; Luz, Paula Mendes; Freedberg, Kenneth A.; Wood, Robin; Levison, Julie H.; Mugyenyi, Peter N.; Salata, Robert; Wallis, Carole L.; Weinstein, Milton C.; Schooley, Robert T.; Walensky, Rochelle P.",Genotype assays and third-line ART in resource-limited settings: a simulation and cost-effectiveness analysis of a planned clinical trial.,"AIDS (London, England)",,1473-5571 0269-9370,10.1097/QAD.0b013e32835221eb,,"OBJECTIVES: To project the clinical and economic outcomes of a genotype assay for selection of third-line antiretroviral therapy (ART) in resource-limited settings, as per the planned international A5288 trial (MULTI-OCTAVE). METHODS: We used the Cost-effectiveness of Preventing AIDS Complications (CEPAC)-International Model to compare three strategies for patients who have failed second-line ART in South Africa: sustained second-line: no genotype assay, all patients remain on second-line ART; A5288: genotype to determine the resistance profile and assign an appropriate regimen; or population-based third-line: no genotype, all patients switch to a potent third-line regimen. Model inputs are from published data in South Africa. Resistance profiles, ART regimens, and efficacy data were those used for trial planning. RESULTS: Projected life expectancy for sustained second-line, A5288, and population-based third-line are 61.1, 103.8, and 104.2 months. Compared to sustained second-line ($12 ,460), per person lifetime costs increase for the A5288 ($39, 250) and population-based ($44, 120) strategies. The incremental cost-effectiveness ratio of A5288, compared to sustained second-line, is $7500/year of life saved (YLS), and for population-based third-line, compared to A5288, is $154 ,500/YLS. In the A5288 strategy, very late presentation to care, coupled with lengthy delays to obtain the genotype, dramatically reduces 5-year survival, making the population-based third-line strategy more attractive. CONCLUSIONS: We project that, whereas the public health approach to third-line therapy is unaffordable, genotype assays and third-line ART in resource-limited settings will increase survival and be cost-effective compared to the population-based approach, supporting the value of an efficacy study.",01/06/2012,26/11/2018 12:52,14/04/2020 08:34,,1083-1093,,9,26,,AIDS,,,,,,,,eng,,,,,,,PMID: 22343964 PMCID: PMC3424271,,,,"Humans; Cost-Benefit Analysis; Treatment Outcome; Female; Male; Middle Aged; Life Expectancy; Models, Biological; 00; South Africa; Anti-HIV Agents/*economics/therapeutic use; Clinical Trials as Topic/*economics; Genotype; HIV Infections/drug therapy/*economics; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VC7D9YX6,journalArticle,2012,"Hartz, Susanne; Getsios, Denis; Tao, Sunning; Blume, Steve; Maclaine, Grant",Evaluating the cost effectiveness of donepezil in the treatment of Alzheimer's disease in Germany using discrete event simulation.,BMC neurology,,1471-2377 1471-2377,10.1186/1471-2377-12-2,,"BACKGROUND: Previous cost-effectiveness studies of cholinesterase inhibitors have modeled Alzheimer's disease (AD) progression and treatment effects through single or global severity measures, or progression to ""Full Time Care"". This analysis evaluates the cost-effectiveness of donepezil versus memantine or no treatment in Germany by considering correlated changes in cognition, behavior and function. METHODS: Rates of change were modeled using trial and registry-based patient level data. A discrete event simulation projected outcomes for three identical patient groups: donepezil 10 mg, memantine 20 mg and no therapy. Patient mix, mortality and costs were developed using Germany-specific sources. RESULTS: Treatment of patients with mild to moderately severe AD with donepezil compared to no treatment was associated with 0.13 QALYs gained per patient, and 0.01 QALYs gained per caregiver and resulted in average savings of euro7,007 and euro9,893 per patient from the healthcare system and societal perspectives, respectively. In patients with moderate to moderately-severe AD, donepezil compared to memantine resulted in QALY gains averaging 0.01 per patient, and savings averaging euro1,960 and euro2,825 from the healthcare system and societal perspective, respectively.In probabilistic sensitivity analyses, donepezil dominated no treatment in most replications and memantine in over 70% of the replications. Donepezil leads to savings in 95% of replications versus memantine. CONCLUSIONS: Donepezil is highly cost-effective in patients with AD in Germany, leading to improvements in health outcomes and substantial savings compared to no treatment. This holds across a variety of sensitivity analyses.",08/02/2012,26/11/2018 12:52,14/04/2020 08:34,,2,,,12,,BMC Neurol,,,,,,,,eng,,,,,,,PMID: 22316501 PMCID: PMC3296601,,,,Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Germany; Memantine/*economics/therapeutic use; 00; Alzheimer Disease/*drug therapy/economics; Cholinesterase Inhibitors/*economics/therapeutic use; Dopamine Agents/*economics/therapeutic use; Indans/*economics/therapeutic use; Piperidines/*economics/therapeutic use; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NERWCDXR,journalArticle,2012,"Posmontier, Bobbie; Montgomery, Kymberlee; Smith Glasgow, Mary Ellen; Montgomery, Owen C.; Morse, Kate",Transdisciplinary teamwork simulation in obstetrics-gynecology health care education.,The Journal of nursing education,,0148-4834 0148-4834,10.3928/01484834-20120127-02,,"This program evaluation was designed to assess whether a transdisciplinary teamwork simulation experience improves collaborative attitudes among women's health students toward the goals of reducing medical errors and improving patient outcomes. This program evaluation used a pretest-posttest comparative design to measure changes in collaborative attitudes among 35 multidisciplinary women's health students before and after a transdisciplinary simulation experience. Collaborative attitudes were measured by the Team Attitudes Questionnaire. Data analysis consisted of descriptive analysis, paired t tests, and post hoc item analysis. Findings suggest significant increases in collaborative attitudes for mutual support and communication but no significant increases in attitudes for structure, situation monitoring, or leadership from pretest to posttest. Trans-disciplinary simulation experiences among women's health students may enhance mutual support and communication and promote better patient outcomes. Future research should focus on mechanisms to facilitate improvements in structure, situation monitoring, and leadership.",2012-03,26/11/2018 12:52,14/04/2020 08:35,,176-179,,3,51,,J Nurs Educ,,,,,,,,eng,"Copyright 2012, SLACK Incorporated.",,,,,,PMID: 22283152,,,,"Humans; United States; Female; Male; *Patient Simulation; Communication; Pregnancy; *Patient Care Team; Obstetric Nursing/education; Attitude of Health Personnel; Cooperative Behavior; *Manikins; 00; *Internship and Residency; Gynecology/education; Obstetrics/education; *Students, Health Occupations; Anesthesiology/education; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PWB54RN9,journalArticle,2012,"Jung, Minsoo",Network analysis as a tool for community capacity measurement and assessing partnerships between community-based organizations in Korea.,The health care manager,,1550-512X 1525-5794,10.1097/HCM.0b013e318242d46e,,"The community partnership is a foundation laid by the local community that has been historically and geographically formed to develop itself. This article, an exploratory community network survey for capacity building, assessed collaborations among community-based organizations (CBOs) in the S-district, Republic of Korea, and evaluated methods for the reconstruction of a resident-governing healthy network. Using CBOs' evaluation questionnaire, the author surveyed 83 CBOs that were collected by snowball sampling. The CBOs in the",2012-03,26/11/2018 12:52,14/04/2020 08:34,,81-93,,1,31,,Health Care Manag (Frederick),,,,,,,,eng,,,,,,,PMID: 22282002,,,,Humans; Surveys and Questionnaires; Female; Male; *Cooperative Behavior; *Community Networks; 00; Republic of Korea; *Capacity Building; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ISXBWNP3,journalArticle,2011,"Larsen, Mark E.; Farmer, Andrew; Weaver, Andrew; Young, Annie; Tarassenko, Lionel",Mobile health for drug dose optimisation.,Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference,,1557-170X 1557-170X,10.1109/IEMBS.2011.6090449,,"Mobile health monitoring in the management of long term conditions has potential benefits for patient care, especially when coupled with active adjustment of medication dosage. We report studies of patient-led self-titration of oral glucose lowering medication (OGLM) and insulin in type 2 diabetes, and dose adjustments (including dose increases) in oral chemotherapy for metastatic colorectal or breast cancer. Monitoring compliance was high in each case, and the feasibility of patients self-titrating OGLM or insulin following an agreed treatment plan was demonstrated. Chemotherapy dose increases supported by detailed toxicity profiles collected by phone have also been demonstrated.",2011,26/11/2018 12:52,14/04/2020 08:34,,1540-1543,,,2011,,Conf Proc IEEE Eng Med Biol Soc,,,,,,,,eng,,,,,,,PMID: 22254614,,,,"Humans; Treatment Outcome; Female; Dose-Response Relationship, Drug; Administration, Oral; 00; Telemedicine/*methods; Insulin/*administration & dosage; Antimetabolites, Antineoplastic/administration & dosage; Blood Glucose Self-Monitoring; Capecitabine; Deoxycytidine/administration & dosage/*analogs & derivatives; Diabetes Mellitus, Type 2/blood/*diagnosis/*drug therapy; Drug Therapy, Computer-Assisted/*methods; Fluorouracil/administration & dosage/*analogs & derivatives; Hypoglycemic Agents/administration & dosage; Neoplasms/diagnosis/*drug therapy; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NLFC87Q7,journalArticle,2012,"Gordon, James A.",As accessible as a book on a library shelf: the imperative of routine simulation in modern health care.,Chest,,1931-3543 0012-3692,10.1378/chest.11-0571,,"Technology-enhanced patient simulation has emerged as an important new modality for teaching and learning in medicine. In particular, immersive simulation platforms that replicate the clinical environment promise to revolutionize medical education by enabling an enhanced level of safety, standardization, and efficiency across health-care training. Such an experiential approach seems unique in reliably catalyzing a level of emotional engagement that fosters immediate and indelible learning and allows for increasingly reliable levels of performance evaluation-all in a completely risk-free environment. As such, medical simulation is poised to emerge as a critical component of training and certification throughout health care, promising to fundamentally enhance quality and safety across disciplines. To encourage routine simulation-based practice as part of its core quality and safety mission, Massachusetts General Hospital now incorporates simulation resources within its historic medical library (est. 1847), located at the center of the campus. In this new model, learners go to the library not only to read about a patient's illness, but also to take care of their ""patient."" Such an approach redefines and advances the central role of the library on the campus and ensures that simulation-based practice is centrally available as part of everyday hospital operations. This article describes the reasons for identifying simulation as an institutional priority leading up to the Massachusetts General Hospital Bicentennial Celebration (1811-2011) and for creating a simulation-based learning laboratory within a hospital library.",2012-01,26/11/2018 12:52,14/04/2020 08:34,,Dec-16,,1,141,,Chest,,,,,,,,eng,,,,,,,PMID: 22215825,,,,"Humans; United States; *Patient Simulation; *Health Services Accessibility; 1; Education, Medical/*methods; Libraries, Medical/*organization & administration; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HVBXWCWE,journalArticle,2011,"Qian, Men-Bao; Chen, Ying-Dan; Fang, Yue-Yi; Xu, Long-Qi; Zhu, Ting-Jun; Tan, Tan; Zhou, Chang-Hai; Wang, Guo-Fei; Jia, Tie-Wu; Yang, Guo-Jing; Zhou, Xiao-Nong",Disability weight of Clonorchis sinensis infection: captured from community study and model simulation.,PLoS neglected tropical diseases,,1935-2735 1935-2727,10.1371/journal.pntd.0001377,,"BACKGROUND: Clonorchiasis is among the most neglected tropical diseases. It is caused by ingesting raw or undercooked fish or shrimp containing the larval of Clonorchis sinensis and mainly endemic in Southeast Asia including China, Korea and Vietnam. The global estimations for population at risk and infected are 601 million and 35 million, respectively. However, it is still not listed among the Global Burden of Disease (GBD) and no disability weight is available for it. Disability weight reflects the average degree of loss of life value due to certain chronic disease condition and ranges between 0 (complete health) and 1 (death). It is crucial parameter for calculating the morbidity part of any disease burden in terms of disability-adjusted life years (DALYs). METHODOLOGY/PRINCIPAL FINDINGS: According to the probability and disability weight of single sequelae caused by C. sinensis infection, the overall disability weight could be captured through Monte Carlo simulation. The probability of single sequelae was gained from one community investigation, while the corresponding disability weight was searched from the literatures in evidence-based approach. The overall disability weights of the male and female were 0.101 and 0.050, respectively. The overall disability weights of the age group of 5-14, 15-29, 30-44, 45-59 and 60+ were 0.022, 0.052, 0.072, 0.094 and 0.118, respectively. There was some evidence showing that the disability weight and geometric mean of eggs per gram of feces (GMEPG) fitted a logarithmic equation. CONCLUSION/SIGNIFICANCE: The overall disability weights of C. sinensis infection are differential in different sex and age groups. The disability weight captured here may be referred for estimating the disease burden of C. sinensis infection.",2011-12,26/11/2018 12:52,14/04/2020 08:35,,e1377,,12,5,,PLoS Negl Trop Dis,,,,,,,,eng,,,,,,,PMID: 22180791 PMCID: PMC3236727,,,,"Humans; Surveys and Questionnaires; Quality-Adjusted Life Years; Adult; Female; Male; Middle Aged; Child; Adolescent; Computer Simulation; Cost of Illness; Child, Preschool; China; Animals; 00; Cholangitis; Clonorchiasis/parasitology/*pathology; Clonorchis sinensis/*isolation & purification; Feces/parasitology; Gallstones; Neglected Diseases/*parasitology/*pathology; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PU7FWZZP,journalArticle,2012,"Mertens, Frederic; Saint-Charles, Johanne; Mergler, Donna",Social communication network analysis of the role of participatory research in the adoption of new fish consumption behaviors.,Social science & medicine (1982),,1873-5347 0277-9536,10.1016/j.socscimed.2011.10.016,,"The formulation and communication of fish advisories are highly complex because of the potential conflict between the nutritional and toxicological issues associated with fish consumption. Government and organization-sponsored fish advisories have had limited success in changing behaviors. Participatory approaches may enhance the understanding of complex issues and the adoption of new behaviors. Here we used social network analysis to investigate the adoption of dietary changes within the context of a community participatory research project. In the Brazilian Amazon, many communities are highly exposed to methylmercury from fish consumption. A participatory intervention based on dietary changes aimed at reducing methylmercury exposure while maintaining fish consumption was initiated in 1995. In 2001, we collected data on individual participation in the research, on the discussion network regarding mercury issues and on changes in fish consumption from 96 of the 110 village households. More than half of men and women had adopted new fish consumption behavior to reduce mercury exposure. Adoption was associated with participation in the research project for both women and men, and with a higher number of discussion partners about mercury issues for women. Adoption was likewise associated with the presence of a female communication partner in the personal networks of both men and women. At the household level, men and women who considered their spouse as a discussion partner were more likely to adopt than those who did not. Opinion le]adership was associated with change in fish consumption only for women. We discuss the contribution of community participation and communication networks to overcome the difficulties in generating complex messages that take into account both health benefits and risks of fish consumption. We also discuss the relevance of building preventive health programs based on participatory research approaches and the roles and relations specific to men and women.",2012-08,26/11/2018 12:52,14/04/2020 08:34,,643-650,,4,75,,Soc Sci Med,,,,,,,,eng,Copyright (c) 2011 Elsevier Ltd. All rights reserved.,,,,,,PMID: 22172976,,,,Humans; Female; Male; Community-Based Participatory Research; Qualitative Research; *Diet; *Communication; Animals; *Social Support; Brazil; Health Promotion/*methods; 00; *Fishes; *Food Contamination; Mercury Poisoning/*prevention & control; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JWYISDNU,journalArticle,2011,"Reister, Gad; Stoffman, Nava",[Improving communication skills of physicians caring for adolescents by simulation].,Harefuah,,0017-7768 0017-7768,,,"Although the unique characteristics and abilities of youths were noted in ancient ages, it was only later that the process of adolescence was studied and understood. Adolescents are considered a healthy population when compared to younger kids and adults. However, unlike other age groups, the morbidity and mortality of adolescents has not decreased in the last decades, probably due to risk-taking behaviors. Since the 1950s, the need for a special medical and health approach in treating adolescents was established. Yet, only a few countries incorporate such approaches when educating and training students, residents and fellows in physicians programs. Youths are treated by physicians of many disciplines, despite the fact that only a minority were trained in adolescent medicine. Simulation of medical situations with standard patients has become a significant tool for improving the communication skills of healthcare providers. The article in this edition of Harefuah describes the use of a simulated-patient-based education system in improving the communication skills of physicians of different fields. The authors presented the positive feedback of the participants in the program and demonstrated that following the program there was a positive influence on their practice when dealing with adolescents. We call to incorporate the teaching of adolescent medicine in all Levels, starting at medical school. Using the simulation tool is very helpful in improving the communication skills of medical personnel.",2011-04,26/11/2018 12:52,14/04/2020 08:35,,"338-339, 420",,4,150,,Harefuah,,,,,,,,heb,,,,,,,PMID: 22164912,,,,"Humans; Program Evaluation; *Patient Simulation; *Physician-Patient Relations; Adolescent; Program Development; *Communication; Adolescent Behavior; 00; Education, Medical/methods; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5MYBI99S,journalArticle,2011,"Hardoff, Daniel; Ziv, Amitai",[Simulated-patient-based educational programs for improvement of physicians' communication skills with adolescents: 7-years experience at the Israel Center For Medical Simulation].,Harefuah,,0017-7768 0017-7768,,,"BACKGROUND: Appropriate communication between healthcare providers and adolescent patients and their parents is the key for successful medical care that recognizes the unique needs of teenagers, who remain their parents' responsibility but deserve individual attention separately. Guidelines addressing adolescents' healthcare have been developed, and include recommendations for appropriate communication with adolescents. Simulated-patient-based education has become a significant tool for improving communication skills of heaLthcare providers. OBJECTIVE: To describe the experience gained at the Israel Center for Medical Simulation (MSRJ during the past 7 years in communication training for physicians who encounter adolescents in their cLinical practice. METHODS: Simulated-patient-based communication workshops were conducted dedicated to physicians who provide healthcare to adolescents. Eight to twelve physicians participated in each workshop, where 8 scenarios were exercised from a pooL of 20 typical scenarios of adolescent-physician encounters that have been prepared at MSR. The participants completed a feedback questionnaire at the end of each workshop regarding its quality, its contribution and its value as an educational tool. RESULTS: Five hundred physicians--pediatricians, family practitioners, gynecologists and military recruitment centers physicians--were trained in simulated-patient-based workshops on communication with adolescents between the years 2002 and 2008. Feedback questionnaires of 470 physicians completed at the end of 41 workshops were surveyed. High ranks were given to all the evaluation issues in the questionnaire. CONCLUSIONS: Training physicians in communication with adolescents at simulated-patient-based workshops is a powerful educational tool, enabling hands-on Learning and application of communication skills. These workshops are highly appreciated and recommended by the participating physicians as useful mechanisms in various medical education Levels.",2011-04,26/11/2018 12:52,14/04/2020 08:34,,"314-317, 422",,4,150,,Harefuah,,,,,,,,heb,,,,,,,PMID: 22164907,,,,"Humans; Program Evaluation; Surveys and Questionnaires; *Patient Simulation; *Physician-Patient Relations; Adolescent; Practice Guidelines as Topic; *Communication; Israel; 00; Education, Medical, Continuing/methods; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3BJE2Y58,journalArticle,2011,"Maire, Nicolas; Shillcutt, Samuel D.; Walker, Damian G.; Tediosi, Fabrizio; Smith, Thomas A.",Cost-effectiveness of the introduction of a pre-erythrocytic malaria vaccine into the expanded program on immunization in sub-Saharan Africa: analysis of uncertainties using a stochastic individual-based simulation model of Plasmodium falciparum malaria.,Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research,,1524-4733 1098-3015,10.1016/j.jval.2011.06.004,,"OBJECTIVE: To evaluate the cost-effectiveness of introducing the RTS,S malaria vaccine into the Expanded Programme on Immunization (EPI) in Sub-Saharan Africa (SSA), the contributions of different sources of uncertainty, and the associated expected value of perfect information (EVPI). METHODS: Vaccination was simulated in populations of 100,000 people at 10 different entomological inoculation rates (EIRs), using an existing stochastic model and a 10-year time horizon. Incremental cost-effectiveness ratios (ICERs) and EVPI were computed from weighted averages of outputs using two different assignments of the EIR distribution in 2007. Uncertainty was evaluated by resampling of epidemiological, vaccination, and health systems model parameters. RESULTS: Health benefits were predicted consistently only at low transmission, and program costs always substantially exceeded case management savings. Optimal cost-effectiveness was at EIR of about 10 infectious bites per annum (ibpa). Main contributors to ICER uncertainty were uncertainty in transmission intensity, price per vaccine dose, decay rate of the vaccine effect, degree of homogeneity in host response, and some epidemiological model parameters. Other health system costs were unimportant. With a ceiling ratio of 207 international dollars per disability-adjusted life-year averted, 52.4% of parameterizations predicted cost-effectiveness in the primary analysis. CONCLUSIONS: Cost-effectiveness of RTS,S will be maximal in low endemicity settings (EIR 2-20 ibpa). Widespread deployment of other transmission-reducing interventions will thus improve cost-effectiveness, suggesting a selective introduction strategy. EVPI is substantial. Accrual of up-to-date information on local endemicity to guide deployment decisions would be highly efficient.",2011-12,26/11/2018 12:52,14/04/2020 08:34,,1028-1038,,8,14,,Value Health,,,,,,,,eng,Copyright (c) 2011 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.,,,,,,PMID: 22152171,,,,"Humans; Cost-Benefit Analysis; Computer Simulation; Models, Theoretical; Immunization Programs/*economics; Africa South of the Sahara/epidemiology; Stochastic Processes; 00; Malaria Vaccines/*administration & dosage/economics; Malaria, Falciparum/economics/epidemiology/*prevention & control; Plasmodium falciparum/immunology/*isolation & purification; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EJWVH9EK,journalArticle,2011,"Goulter, Nicole",Simulation in mental health education.,Australian nursing journal (July 1993),,1320-3185 1320-3185,,,,2011-10,26/11/2018 12:52,14/04/2020 08:34,,41,,4,19,,Aust Nurs J,,,,,,,,eng,,,,,,,PMID: 22132530,,,,Humans; *Patient Simulation; Psychiatric Nursing/*education; 00; *MP3-Player; Queensland; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CZFEX5U4,journalArticle,2011,"Boros, Mihaly","[To the editors: comment regarding the article ""Innovative education: simulation-based training at the Institute of Health Sciences, Semmelweis University, Hungary""].",Orvosi hetilap,,0030-6002 0030-6002,10.1556/OH.2011.51M,,,18/12/2011,26/11/2018 12:52,14/04/2020 08:34,,2067; author reply 2068-2069,,51,152,,Orv Hetil,,,,,,,,hun,,,,,,,PMID: 22130205,,,,"Humans; *Manikins; 00; Education, Public Health Professional/*methods; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QMESH6FK,journalArticle,2012,"Unsworth, J.; McKeever, M.; Kelleher, M.",Recognition of physical deterioration in patients with mental health problems: the role of simulation in knowledge and skill development.,Journal of psychiatric and mental health nursing,,1365-2850 1351-0126,10.1111/j.1365-2850.2011.01828.x,,"Recognition of physical deterioration in patients with mental health problems has been recognized as a significant problem. Areas of particular concern include rapid tranquilization, physical restraint, the consumption of alcohol and illicit drugs have the potential to result in sudden and catastrophic patient deterioration. Simulation sessions, using patient mannequins, are widely used to support the education of nurses but its use in mental health has been somewhat restricted. The aim of this study was to design and deliver simulation scenarios to develop the skills and knowledge of mental health nursing students in the recognition and management of physical deterioration. A series of three scenarios were developed and delivered to a group of final-year nursing students. Evaluation of the sessions was undertaken using analysis of video footage from the sessions and through two focus groups. The results show that simulation is a useful catalyst for discrepancy creation which in turn leads to the student focusing their future learning towards addressing any identified deficits in skills and knowledge identified. Authenticity of the simulation sessions also plays a role in ensuring student engagement and faculty support during sessions is vital to support the students in managing unfamiliar situations.",2012-08,26/11/2018 12:52,14/04/2020 08:35,,536-545,,6,19,,J Psychiatr Ment Health Nurs,,,,,,,,eng,(c) 2011 Blackwell Publishing.,,,,,,PMID: 22074049,,,,"Humans; Clinical Competence; *Patient Simulation; Psychiatric Nursing/*education; 00; Students, Nursing; Mental Disorders/*complications/diagnosis/psychology; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DAR82537,journalArticle,2012,"Guise, V.; Chambers, M.; Valimaki, M.",What can virtual patient simulation offer mental health nursing education?,Journal of psychiatric and mental health nursing,,1365-2850 1351-0126,10.1111/j.1365-2850.2011.01797.x,,"This paper discusses the use of simulation in nursing education and training, including potential benefits and barriers associated with its use. In particular, it addresses the hitherto scant application of diverse simulation devices and dedicated simulation scenarios in psychiatric and mental health nursing. It goes on to describe a low-cost, narrative-based virtual patient simulation technique which has the potential for wide application within health and social care education. An example of the implementation of this technology in a web-based pilot course for acute mental health nurses is given. This particular virtual patient technique is a simulation type ideally suited to promoting essential mental health nursing skills such as critical thinking, communication and decision making. Furthermore, it is argued that it is particularly amenable to e-learning and blended learning environments, as well as being an apt tool where multilingual simulations are required. The continued development, implementation and evaluation of narrative virtual patient simulations across a variety of health and social care programmes would help ascertain their success as an educational tool.",2012-06,26/11/2018 12:52,14/04/2020 08:34,,410-418,,5,19,,J Psychiatr Ment Health Nurs,,,,,,,,eng,(c) 2011 Blackwell Publishing.,,,,,,PMID: 22070549,,,,"Humans; *Patient Simulation; Psychiatric Nursing/*education; United Kingdom; Video Games; User-Computer Interface; Computer-Assisted Instruction/*methods; 00; Problem-Based Learning/methods; Education, Distance/*methods; Mental Disorders/*nursing; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2WS9742E,journalArticle,2012,"Hajos, T. R. S.; Pouwer, F.; de Grooth, R.; Holleman, F.; Twisk, J. W. R.; Diamant, M.; Snoek, F. J.",The longitudinal association between glycaemic control and health-related quality of life following insulin therapy optimisation in type 2 diabetes patients. A prospective observational study in secondary care.,"Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation",,1573-2649 0962-9343,10.1007/s11136-011-0051-0,,"PURPOSE: To test whether improvement in glycosylated haemoglobin (HbA(1c)) as a marker of glycaemic control, following intensifying insulin therapy, is associated with improvements in HRQoL. METHODS: Dutch sub-optimally controlled (HbA(1c) > 7%) type 2 diabetes patients (N = 447, mean age 59 +/- 11) initiated insulin glargine therapy. Data were collected at baseline, 3 and 6 months, and included HbA(1c) and measures of HRQoL: diabetes symptom distress (Diabetes Symptom Checklist-revised; DSC-r), fear of hypoglycaemia (Hypoglycaemia Fear Survey; HFS-w) and emotional well-being (WHO-5 wellbeing index). RESULTS: HbA(1c) decreased from 8.8 +/- 1.4% to 8.0 +/- 1.2% and 7.7 +/- 1.3% at 3 and 6 months follow-up, respectively (P < 0.001), DSC-r score improved from 17.7 +/- 14.7 to 14.3 +/- 13.3 and 13.6 +/- 13.3 (P < 0.001). HFS-w score did not significantly change. WHO-5 score increased from 56 +/- 23 to 62 +/- 23 and 65 +/- 22 P < 0.001). A modest, significant association was found between HbA(1c) and WHO-5 score (B = -1.8, 95% CI: -2.7 to -0.8) and HbA1c and DSC-r score (B = 1.0, 95% CI: 0.4 to 1.6). No such association was found for HFS-w score. CONCLUSIONS: An association between improvement in HbA(1c) by means of optimising insulin therapy and improvement in HRQoL in type 2 diabetes patients has been observed. A weak, yet significant longitudinal association was found between improved HbA(1c) and emotional well-being and diabetes symptom distress.",2012-10,26/11/2018 12:52,14/04/2020 08:34,,1359-1365,,8,21,,Qual Life Res,,,,,,,,eng,,,,,,,PMID: 22065281 PMCID: PMC3438404,,,,"Humans; Health Status Indicators; Netherlands; Female; Male; Middle Aged; Prospective Studies; Adaptation, Psychological; Quality of Life/*psychology; 00; Psychometrics; Stress, Psychological; Blood Glucose/*analysis/metabolism; Diabetes Mellitus, Type 2/drug therapy/*psychology; Glycated Hemoglobin A/analysis; Hypoglycemic Agents/administration & dosage/*therapeutic use; Insulin/administration & dosage/*therapeutic use; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QTS8NQXK,journalArticle,2011,"Burden, C.; Oestergaard, J.; Larsen, C. R.",Integration of laparoscopic virtual-reality simulation into gynaecology training.,BJOG : an international journal of obstetrics and gynaecology,,1471-0528 1470-0328,10.1111/j.1471-0528.2011.03174.x,,"Surgery carries the risk of serious harm, as well as benefit, to patients. For healthcare organisations, theatre time is an expensive commodity and litigation costs for surgical specialities are very high. Advanced laparoscopic surgery, now widely used in gynaecology for improved outcomes and reduced length of stay, involves longer operation times and a higher rate of complications for surgeons in training. Virtual-reality (VR) simulation is a relatively new training method that has the potential to promote surgical skill development before advancing to surgery on patients themselves. VR simulators have now been on the market for more than 10 years and, yet, few countries in the world have fully integrated VR simulation training into their gynaecology surgical training programmes. In this review, we aim to summarise the VR simulators currently available together with evidence of their effectiveness in gynaecology, to understand their limitations and to discuss their incorporation into national training curricula.",2011-11,26/11/2018 12:52,14/04/2020 08:34,,05-Oct,,,118 Suppl 3,,BJOG,,,,,,,,eng,(c) 2011 The Authors BJOG An International Journal of Obstetrics and Gynaecology (c) 2011 RCOG.,,,,,,PMID: 22039886,,,,Humans; Curriculum; Costs and Cost Analysis; Cooperative Behavior; *User-Computer Interface; Feedback; 00; Gynecology/*education; Computer-Assisted Instruction/economics/*instrumentation; Laparoscopy/*education; Validation Studies as Topic; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, R84T6BRR,journalArticle,2012,"Knerer, Gerhart; Ismaila, Afisi; Pearce, David",Health and economic impact of PHiD-CV in Canada and the UK: a Markov modelling exercise.,Journal of medical economics,,1941-837X 1369-6998,10.3111/13696998.2011.622323,,"OBJECTIVE: The spectrum of diseases caused by Streptococcus pneumoniae and non-typeable Haemophilus influenzae (NTHi) represents a large burden on healthcare systems around the world. Meningitis, bacteraemia, community-acquired pneumonia (CAP), and acute otitis media (AOM) are vaccine-preventable infectious diseases that can have severe consequences. The health economic model presented here is intended to estimate the clinical and economic impact of vaccinating birth cohorts in Canada and the UK with the 10-valent, pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) compared with the newly licensed 13-valent pneumococcal conjugate vaccine (PCV-13). METHODS: The model described herein is a Markov cohort model built to simulate the epidemiological burden of pneumococcal- and NTHi-related diseases within birth cohorts in the UK and Canada. Base-case assumptions include estimates of vaccine efficacy and NTHi infection rates that are based on published literature. RESULTS: The model predicts that the two vaccines will provide a broadly similar impact on all-cause invasive disease and CAP under base-case assumptions. However, PHiD-CV is expected to provide a substantially greater reduction in AOM compared with PCV-13, offering additional savings of Canadian $9.0 million and pound4.9 million in discounted direct medical costs in Canada and the UK, respectively. LIMITATIONS: The main limitations of the study are the difficulties in modelling indirect vaccine effects (herd effect and serotype replacement), the absence of PHiD-CV- and PCV-13-specific efficacy data and a lack of comprehensive NTHi surveillance data. Additional limitations relate to the fact that the transmission dynamics of pneumococcal serotypes have not been modelled, nor has antibiotic resistance been accounted for in this paper. CONCLUSION: This cost-effectiveness analysis suggests that, in Canada and the UK, PHiD-CV's potential to protect against NTHi infections could provide a greater impact on overall disease burden than the additional serotypes contained in PCV-13.",2012,26/11/2018 12:52,14/04/2020 08:34,,61-76,,1,15,,J Med Econ,,,,,,,,eng,,,,,,,PMID: 22026590,,,,"Humans; Canada; Outcome Assessment (Health Care); Cost-Benefit Analysis; Adult; Middle Aged; Young Adult; Aged; Markov Chains; Child; Adolescent; Child, Preschool; United Kingdom; 00; Bacterial Proteins/*economics/therapeutic use; Carrier Proteins/*economics/therapeutic use; Immunoglobulin D/*economics/therapeutic use; Lipoproteins/*economics/therapeutic use; Vaccines, Conjugate/*economics/therapeutic use; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 43P9G5WY,journalArticle,2011,"Fialho, Andre S.; Oliveira, Monica D.; Sa, Armando B.",Using discrete event simulation to compare the performance of family health unit and primary health care centre organizational models in Portugal.,BMC health services research,,1472-6963 1472-6963,10.1186/1472-6963-11-274,,"BACKGROUND: Recent reforms in Portugal aimed at strengthening the role of the primary care system, in order to improve the quality of the health care system. Since 2006 new policies aiming to change the organization, incentive structures and funding of the primary health care sector were designed, promoting the evolution of traditional primary health care centres (PHCCs) into a new type of organizational unit--family health units (FHUs). This study aimed to compare performances of PHCC and FHU organizational models and to assess the potential gains from converting PHCCs into FHUs. METHODS: Stochastic discrete event simulation models for the two types of organizational models were designed and implemented using Simul8 software. These models were applied to data from nineteen primary care units in three municipalities of the Greater Lisbon area. RESULTS: The conversion of PHCCs into FHUs seems to have the potential to generate substantial improvements in productivity and accessibility, while not having a significant impact on costs. This conversion might entail a 45% reduction in the average number of days required to obtain a medical appointment and a 7% and 9% increase in the average number of medical and nursing consultations, respectively. CONCLUSIONS: Reorganization of PHCC into FHUs might increase accessibility of patients to services and efficiency in the provision of primary care services.",15/10/2011,26/11/2018 12:52,14/04/2020 08:34,,274,,,11,,BMC Health Serv Res,,,,,,,,eng,,,,,,,PMID: 21999336 PMCID: PMC3214168,,,,"*Health Care Reform; Humans; Health Services Research; Computer Simulation; Models, Organizational; Health Services Accessibility/*statistics & numerical data; Primary Health Care/*organization & administration; 1; Family Practice/*organization & administration; Portugal; Efficiency, Organizational/*statistics & numerical data; Discrete event; 310",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DQFSNGNW,journalArticle,2011,"Dunn, William F.; Murphy, Joseph G.; Ziv, Amitai","Reengineering health care via medical simulation tools: ""Lions and tigers and bears. Oh my!"".",Chest,,1931-3543 0012-3692,10.1378/chest.11-1541,,,2011-10,26/11/2018 12:52,14/04/2020 08:34,,840-843,,4,140,,Chest,,,,,,,,eng,,,,,,,PMID: 21972377,,,,"Humans; Patient Safety/*standards; Computer Simulation/*trends; 00; Education, Medical/*trends; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Z4VAP3EB,journalArticle,2011,"Higashi, Hideki; Barendregt, Jan J.",Cost-effectiveness of total hip and knee replacements for the Australian population with osteoarthritis: discrete-event simulation model.,PloS one,,1932-6203 1932-6203,10.1371/journal.pone.0025403,,"BACKGROUND: Osteoarthritis constitutes a major musculoskeletal burden for the aged Australians. Hip and knee replacement surgeries are effective interventions once all conservative therapies to manage the symptoms have been exhausted. This study aims to evaluate the cost-effectiveness of hip and knee replacements in Australia. To our best knowledge, the study is the first attempt to account for the dual nature of hip and knee osteoarthritis in modelling the severities of right and left joints separately. METHODOLOGY/PRINCIPAL FINDINGS: We developed a discrete-event simulation model that follows up the individuals with osteoarthritis over their lifetimes. The model defines separate attributes for right and left joints and accounts for several repeat replacements. The Australian population with osteoarthritis who were 40 years of age or older in 2003 were followed up until extinct. Intervention effects were modelled by means of disability-adjusted life-years (DALYs) averted. Both hip and knee replacements are highly cost effective (AUD 5,000 per DALY and AUD 12,000 per DALY respectively) under an AUD 50,000/DALY threshold level. The exclusion of cost offsets, and inclusion of future unrelated health care costs in extended years of life, did not change the findings that the interventions are cost-effective (AUD 17,000 per DALY and AUD 26,000 per DALY respectively). However, there was a substantial difference between hip and knee replacements where surgeries administered for hips were more cost-effective than for knees. CONCLUSIONS/SIGNIFICANCE: Both hip and knee replacements are cost-effective interventions to improve the quality of life of people with osteoarthritis. It was also shown that the dual nature of hip and knee OA should be taken into account to provide more accurate estimation on the cost-effectiveness of hip and knee replacements.",2011,26/11/2018 12:52,14/04/2020 08:34,,e25403,,9,6,,PLoS One,,,,,,,,eng,,,,,,,PMID: 21966520 PMCID: PMC3179521,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Adult; Female; Male; Australia; Arthroplasty, Replacement, Knee/*economics; Discrete event simulation; 1; Arthroplasty, Replacement, Hip/*economics; Osteoarthritis, Hip/*surgery; Osteoarthritis, Knee/*surgery; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, W52XCVG8,journalArticle,2012,"Chen, Zhuo; Roy, Kakoli; Gotway Crawford, Carol A.",Evaluation of variance estimators for the concentration and health achievement indices: a Monte Carlo simulation.,Health economics,,1099-1050 1057-9230,10.1002/hec.1796,,"Although the concentration index (CI) and the health achievement index (HAI) have been extensively used, previous studies have relied on bootstrapping to compute the variance of the HAI, whereas competing variance estimators exist for the CI. This paper provides methods of statistical inference for the HAI and compares the available variance estimators for both the CI and the HAI using Monte Carlo simulation. Results for both the CI and the HAI suggest that analytical methods and bootstrapping are well behaved. The convenient regression method gives standard errors close to the other methods, provided the CI is not too large (< 0.2), but otherwise tends to understate the standard errors. In our simulation setting, the improvement from the Newey-West correction over the convenient regression method has mixed evidence when the CI 0.1. Published 2011. This article is a US Government work and is in the public domain in the USA.",2012-11,26/11/2018 12:52,14/04/2020 08:34,,1375-1381,,11,21,,Health Econ,,,,,,,,eng,Published 2011. This article is a US Government work and is in the public domain in the USA.,,,,,,PMID: 21956946,,,,"Humans; United States; *Health Status; Models, Statistical; Regression Analysis; *Monte Carlo Method; Confidence Intervals; 1; *Analysis of Variance; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, K5MPPQJD,journalArticle,2011,"Cook, David A.; Hatala, Rose; Brydges, Ryan; Zendejas, Benjamin; Szostek, Jason H.; Wang, Amy T.; Erwin, Patricia J.; Hamstra, Stanley J.",Technology-enhanced simulation for health professions education: a systematic review and meta-analysis.,JAMA,,1538-3598 0098-7484,10.1001/jama.2011.1234,,"CONTEXT: Although technology-enhanced simulation has widespread appeal, its effectiveness remains uncertain. A comprehensive synthesis of evidence may inform the use of simulation in health professions education. OBJECTIVE: To summarize the outcomes of technology-enhanced simulation training for health professions learners in comparison with no intervention. DATA SOURCE: Systematic search of MEDLINE, EMBASE, CINAHL, ERIC, PsychINFO, Scopus, key journals, and previous review bibliographies through May 2011. STUDY SELECTION: Original research in any language evaluating simulation compared with no intervention for training practicing and student physicians, nurses, dentists, and other health care professionals. DATA EXTRACTION: Reviewers working in duplicate evaluated quality and abstracted information on learners, instructional design (curricular integration, distributing training over multiple days, feedback, mastery learning, and repetitive practice), and outcomes. We coded skills (performance in a test setting) separately for time, process, and product measures, and similarly classified patient care behaviors. DATA SYNTHESIS: From a pool of 10,903 articles, we identified 609 eligible studies enrolling 35,226 trainees. Of these, 137 were randomized studies, 67 were nonrandomized studies with 2 or more groups, and 405 used a single-group pretest-posttest design. We pooled effect sizes using random effects. Heterogeneity was large (I(2)>50%) in all main analyses. In comparison with no intervention, pooled effect sizes were 1.20 (95% CI, 1.04-1.35) for knowledge outcomes (n = 118 studies), 1.14 (95% CI, 1.03-1.25) for time skills (n = 210), 1.09 (95% CI, 1.03-1.16) for process skills (n = 426), 1.18 (95% CI, 0.98-1.37) for product skills (n = 54), 0.79 (95% CI, 0.47-1.10) for time behaviors (n = 20), 0.81 (95% CI, 0.66-0.96) for other behaviors (n = 50), and 0.50 (95% CI, 0.34-0.66) for direct effects on patients (n = 32). Subgroup analyses revealed no consistent statistically significant interactions between simulation training and instructional design features or study quality. CONCLUSION: In comparison with no intervention, technology-enhanced simulation training in health professions education is consistently associated with large effects for outcomes of knowledge, skills, and behaviors and moderate effects for patient-related outcomes.",07/09/2011,26/11/2018 12:52,14/04/2020 08:34,,978-988,,9,306,,JAMA,,,,,,,,eng,,,,,,,PMID: 21900138,,,,"Humans; *Computer Simulation; Health Personnel/*education; *Computer-Assisted Instruction; Education, Professional/*methods; 00; Education, Medical/*methods; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, K2DXUY4K,journalArticle,2011,"Holloway, Elizabeth; Kusy, Mitchell",Systems approach to address incivility and disruptive behaviors in health-care organizations.,Advances in health care management,,1474-8231 1474-8231,,,"In response to the growing evidence that disruptive behaviors within health-care teams constitute a major threat to the quality of care, the Joint Commission on Accreditation of Healthcare Organization (JCAHO; Joint Commission Resources, 2008) has a new leadership standard that addresses disruptive and inappropriate behaviors effective January 1, 2009. For professionals who work in human resources and organization development, these standards represent a clarion call to design and implement evidence-based interventions to create health-care communities of respectful engagement that have zero tolerance for disruptive, uncivil, and intimidating behaviors by any professional. In this chapter, we will build an evidence-based argument that sustainable change must include organizational, team, and individual strategies across all professionals in the organization. We will then describe an intervention model--Toxic Organization Change System--that has emerged from our own research on toxic behaviors in the workplace (Kusy & Holloway, 2009) and provide examples of specific strategies that we have used to prevent and ameliorate toxic cultures.",2011,26/11/2018 12:52,14/04/2020 08:34,,239-265,,,10,,Adv Health Care Manag,,,,,,,,eng,,,,,,,PMID: 21887948,,,,Humans; United States; *Interprofessional Relations; *Leadership; Organizational Culture; Guidelines as Topic; 00; Patient Care Team/organization & administration/standards; Delivery of Health Care/*organization & administration/standards; *Agonistic Behavior; *Hostility; Institutional Management Teams/organization & administration/standards; Joint Commission on Accreditation of Healthcare Organizations; Organizational Policy; Social Dominance; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PC842YVI,journalArticle,2012,"Herrick, Robert L.; Buchberger, Steven G.; Clark, Robert M.; Kupferle, Margaret; Murray, Regan; Succop, Paul","A Markov model to estimate Salmonella morbidity, mortality, illness duration, and cost.",Health economics,,1099-1050 1057-9230,10.1002/hec.1779,,"Approximately 690000-1790000 Salmonella cases, 20000 hospitalizations, and 400 deaths occur in the USA annually, costing approximately $2.6bn. Existing models estimate morbidity, mortality, and cost solely from incidence. They do not estimate illness duration or use time as an independent cost predictor. Existing models may underestimate physician visits, hospitalizations, deaths, and associated costs. We developed a Markov chain Monte Carlo model to estimate illness duration, physician/emergency room visits, inpatient hospitalizations, mortality, and resultant costs for a given Salmonella incidence. Interested parties include society, third-party payers, health providers, federal, state and local governments, businesses, and individual patients and their families. The marginal approach estimates individual disease behavior for every patient, explicitly estimates disease duration and calculates separate time-dependent costs. The aggregate approach is a Markov equivalent of the existing models; it assumes average disease behavior and cost for a given morbidity/mortality. Transition probabilities were drawn from a meta-analysis of 53 Salmonella studies. Both approaches were tested using the 1993 Salmonella typhimurium outbreak in Gideon, Missouri. This protocol can be applied to estimate morbidity, mortality and cost of specific outbreaks, provide better national Salmonella burden estimates, and estimate the benefits of reducing Salmonella risk.",2012-10,26/11/2018 12:52,14/04/2020 08:34,,1169-1182,,10,21,,Health Econ,,,,,,,,eng,"Copyright (c) 2011 John Wiley & Sons, Ltd.",,,,,,PMID: 21887809,,,,"Humans; *Markov Chains; Monte Carlo Method; Incidence; Time Factors; Models, Economic; *Cost of Illness; Morbidity; 1; Health Expenditures/statistics & numerical data; Health Services/*economics/utilization; Salmonella Infections/*economics/*epidemiology/mortality; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JKARTBLQ,journalArticle,2011,"Arial, Marc; Wild, Pascal","Effort, reward and self-reported mental health: a simulation study on negative affectivity bias.",BMC medical research methodology,,1471-2288 1471-2288,10.1186/1471-2288-11-121,,"BACKGROUND: In the present article, we propose an alternative method for dealing with negative affectivity (NA) biases in research, while investigating the association between a deleterious psychosocial environment at work and poor mental health. First, we investigated how strong NA must be to cause an observed correlation between the independent and dependent variables. Second, we subjectively assessed whether NA can have a large enough impact on a large enough number of subjects to invalidate the observed correlations between dependent and independent variables. METHODS: We simulated 10,000 populations of 300 subjects each, using the marginal distribution of workers in an actual population that had answered the Siegrist's questionnaire on effort and reward imbalance (ERI) and the General Health Questionnaire (GHQ). RESULTS: The results of the present study suggested that simulated NA has a minimal effect on the mean scores for effort and reward. However, the correlations between the effort and reward imbalance (ERI) ratio and the GHQ score might be important, even in simulated populations with a limited NA. CONCLUSIONS: When investigating the relationship between the ERI ratio and the GHQ score, we suggest the following rules for the interpretation of the results: correlations with an explained variance of 5% and below should be considered with caution; correlations with an explained variance between 5% and 10% may result from NA, although this effect does not seem likely; and correlations with an explained variance of 10% and above are not likely to be the result of NA biases.",24/08/2011,26/11/2018 12:52,14/04/2020 08:34,,121,,,11,,BMC Med Res Methodol,,,,,,,,eng,,,,,,,PMID: 21864350 PMCID: PMC3170295,,,,"Humans; *Computer Simulation; Bias; *Models, Psychological; 00; *Mental Health; *Reward; *Self Report; Mental Disorders/diagnosis/epidemiology/etiology; Stress, Psychological/complications; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NK4PQ3R6,journalArticle,2011,"Tran-Duy, An; Boonen, Annelies; van de Laar, Mart A. F. J.; Franke, Angelinus C.; Severens, Johan L.",A discrete event modelling framework for simulation of long-term outcomes of sequential treatment strategies for ankylosing spondylitis.,Annals of the rheumatic diseases,,1468-2060 0003-4967,10.1136/annrheumdis-2011-200333,,"OBJECTIVE: To develop a modelling framework which can simulate long-term quality of life, societal costs and cost-effectiveness as affected by sequential drug treatment strategies for ankylosing spondylitis (AS). METHODS: Discrete event simulation paradigm was selected for model development. Drug efficacy was modelled as changes in disease activity (Bath Ankylosing Spondylitis Disease Activity Index (BASDAI)) and functional status (Bath Ankylosing Spondylitis Functional Index (BASFI)), which were linked to costs and health utility using statistical models fitted based on an observational AS cohort. Published clinical data were used to estimate drug efficacy and time to events. Two strategies were compared: (1) five available non-steroidal anti-inflammatory drugs (strategy 1) and (2) same as strategy 1 plus two tumour necrosis factor alpha inhibitors (strategy 2). 13,000 patients were followed up individually until death. For probability sensitivity analysis, Monte Carlo simulations were performed with 1000 sets of parameters sampled from the appropriate probability distributions. RESULTS: The models successfully generated valid data on treatments, BASDAI, BASFI, utility, quality-adjusted life years (QALYs) and costs at time points with intervals of 1-3 months during the simulation length of 70 years. Incremental cost per QALY gained in strategy 2 compared with strategy 1 was euro35,186. At a willingness-to-pay threshold of euro80,000, it was 99.9% certain that strategy 2 was cost-effective. CONCLUSIONS: The modelling framework provides great flexibility to implement complex algorithms representing treatment selection, disease progression and changes in costs and utilities over time of patients with AS. Results obtained from the simulation are plausible.",2011-12,26/11/2018 12:52,14/04/2020 08:35,,2111-2118,,12,70,,Ann Rheum Dis,,,,,,,,eng,,,,,,,PMID: 21857027,,,,"Humans; Netherlands; Cost-Benefit Analysis; Quality-Adjusted Life Years; Treatment Outcome; Adult; Female; Male; Health Care Costs/statistics & numerical data; Algorithms; Severity of Illness Index; Cost of Illness; Models, Statistical; Disease Progression; *Models, Econometric; Drug Therapy, Combination; 1; Anti-Inflammatory Agents, Non-Steroidal/economics/*therapeutic use; Antirheumatic Agents/economics/therapeutic use; Health Resources/utilization; Spondylitis, Ankylosing/*drug therapy/economics; Tumor Necrosis Factor-alpha/antagonists & inhibitors; 100; 120",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3F5TMNQS,journalArticle,2012,"Blanchet, Karl; James, Philip",How to do (or not to do) ... a social network analysis in health systems research.,Health policy and planning,,1460-2237 0268-1080,10.1093/heapol/czr055,,"The main challenges in international health are to scale up effective health interventions in low- and middle-income countries in order to reach a higher proportion of the population. This can be achieved through better insight into how health systems are structured. Social network analysis can provide an appropriate and innovative paradigm for the health systems researcher, allow new analyses of the structure of health systems, and facilitate understanding of the role of stakeholders within a health system. The social network analysis methodology adapted to health systems research and described in detail by the authors comprises three main stages: (i) describing the set of actors and members of the network; (ii) characterizing the relationships between actors; and (iii) analysing the structure of the systems. Evidence generated through social network analysis could help policy makers to understand how health systems react over time and to better adjust health programmes and innovations to the capacities of health systems in low- and middle-income countries to achieve universal coverage.",2012-08,26/11/2018 12:52,14/04/2020 08:34,,438-446,,5,27,,Health Policy Plan,,,,,,,,eng,,,,,,,PMID: 21840934,,,,Delivery of Health Care/*organization & administration; Humans; Health Services Research/*methods; *Social Support; 1; Developing Countries; Network analysis; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6I76H975,journalArticle,2011,"Reynolds, Ana; Ayres-de-Campos, Diogo; Lobo, Mariana",Self-perceived impact of simulation-based training on the management of real-life obstetrical emergencies.,"European journal of obstetrics, gynecology, and reproductive biology",,1872-7654 0301-2115,10.1016/j.ejogrb.2011.07.022,,"OBJECTIVE: To evaluate the self-perceived impact of attending a simulation-based training course on the management of real-life obstetrical emergencies. STUDY DESIGN: A prospective follow-up study was conducted. Obstetric nurses and obstetricians (n=54) from a tertiary care university hospital participated in a simulation-based training course for the management of four obstetric emergencies. One year after the last session of the course, participants were asked to complete a questionnaire evaluating the self-perceived impact it had on their knowledge, technical skills, and teamwork skills during experienced real-life situations. A five-point Likert grading scale was used. The chi(2) test with one degree of freedom or the Fisher's exact test were used to compare groups of participants. The t-test for independent samples was used to compare mean scores between groups. RESULTS: A total of 46 healthcare professionals answered the questionnaire: 27 obstetricians and 19 obstetric nurses. Of these, 87% perceived an improvement (scores 4 or 5) in their knowledge and skills during real emergencies. Obstetric nurses expressed a significantly higher improvement than obstetricians in their ability to diagnose or be aware of obstetrical emergencies (p=0.002), in their technical skills (p=0.024), and in their ability to deal with teamwork related issues (p=0.005). Participants who had experienced in real-life situations all four simulated scenarios rated the impact of training significantly higher than others (p=0.049), and also reported a better improvement in their knowledge of management guidelines (p=0.006). CONCLUSIONS: Healthcare professionals who participated in a simulation-based training course in obstetrical emergencies perceived a substantial improvement in their knowledge and skills when witnessing real-life emergencies. Improvements seem to be particularly relevant for obstetric nurses and for those who witness all trained obstetrical emergencies.",2011-11,26/11/2018 12:52,14/04/2020 08:35,,72-76,,1,159,,Eur J Obstet Gynecol Reprod Biol,,,,,,,,eng,Copyright (c) 2011 Elsevier Ireland Ltd. All rights reserved.,,,,,,PMID: 21831504,,,,"Humans; Female; *Patient Simulation; Follow-Up Studies; Patient Care Team; Pregnancy; Obstetric Labor Complications/therapy; Prospective Studies; Hospitals, University; Inservice Training/*methods; *Professional Competence; Emergency Medical Services; 00; Obstetrics/*education; Self Report; *Models, Anatomic; Portugal; Fetal Diseases/therapy; Obstetric Nursing/*education; Obstetrics and Gynecology Department, Hospital/manpower; Pregnancy Complications/*therapy; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6C97CE7A,journalArticle,2011,"Chan, Kee; Davis, Joie; Pai, Sung-Yun; Bonilla, Francisco A.; Puck, Jennifer M.; Apkon, Michael",A Markov model to analyze cost-effectiveness of screening for severe combined immunodeficiency (SCID).,Molecular genetics and metabolism,,1096-7206 1096-7192,10.1016/j.ymgme.2011.07.007,,"OBJECTIVE: To evaluate the cost-effectiveness of universal neonatal screening for T cell lymphocytopenia in enhancing quality of life and life expectancy for children with severe combined immunodeficiency (SCID). METHODS: Decision trees were created and analyzed to estimate the cost, life years, and quality adjusted life years (QALYs) across a population when universal screening for lack of T cells is used to detect SCID, as implemented in five states, compared to detection based on recognizing symptoms and signs of disease. Terminal values of each tree limb were derived through Markov models simulating the natural history of three cohorts: unaffected subjects; those diagnosed with SCID as neonates (early diagnosis); and those diagnosed after becoming symptomatic and arousing clinical suspicion (late diagnosis). Models considered the costs of screening and of care including hematopoietic cell transplantation for affected individuals. Key decision variables were derived from the literature and from a survey of families with children affected by SCID, which was used to describe the clinical history and healthcare utilization for affected subjects. Sensitivity analyses were conducted to explore the influence of these decision variables. RESULTS: Over a 70-year time horizon, the average cost per infant was $8.89 without screening and $14.33 with universal screening. The model predicted that universal screening in the U.S. would cost approximately $22.4 million/year with a gain of 880 life years and 802 QALYs. Sensitivity analyses showed that screening test specificity and disease incidence were critical driving forces affecting the incremental cost-effectiveness ratio (ICER). Assuming a SCID incidence of 1/75,000 births and test specificity and sensitivity each at 0.99, screening remained cost-effective up to a maximum cost of $15 per infant screened. CONCLUSION: At our current estimated screening cost of $4.22/infant, universal screening for SCID would be a cost effective means to improve quality and duration of life for children with SCID.",2011-11,26/11/2018 12:52,14/04/2020 08:34,,383-389,,3,104,,Mol Genet Metab,,,,,,,,eng,Copyright A(c) 2011 Elsevier Inc. All rights reserved.,,,,,,PMID: 21810544 PMCID: PMC3205197,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; *Models, Economic; Markov Chains; Decision Trees; Sensitivity and Specificity; Infant, Newborn; Neonatal Screening/*economics/*methods; *T-Lymphocytes; Lymphopenia/*diagnosis; Severe Combined Immunodeficiency/*diagnosis; 1; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3RNNTS38,journalArticle,2012,"Farley, Jason E.; Doughman, Danielle; Jeeva, Rani; Jeffries, Pamela; Stanley, Joan M.",Department of Health and Human Services releases new immersive simulation experience to improve infection control knowledge and practices among health care workers and students.,American journal of infection control,,1527-3296 0196-6553,10.1016/j.ajic.2011.03.024,,"In this article, we review a newly developed evidence-based immersive simulation experience for use with health care personnel and students. The article provides information necessary for infection control professionals to understand the development process of the training. Evidence supporting the use of such training is provided, and opportunities to integrate this training into the health care setting and classroom are discussed.",2012-04,26/11/2018 12:52,14/04/2020 08:34,,258-259,,3,40,,Am J Infect Control,,,,,,,,eng,"Copyright (c) 2012 Association for Professionals in Infection Control and Epidemiology, Inc. All rights reserved.",,,,,,PMID: 21784556,,,,"Humans; United States; Computer Simulation; *Health Personnel; *Health Knowledge, Attitudes, Practice; Infection Control/*methods; 00; *Students, Medical; Education, Medical/*methods; United States Dept. of Health and Human Services; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, AEPH3466,journalArticle,2011,"Diez Roux, Ana V.",Complex systems thinking and current impasses in health disparities research.,American journal of public health,,1541-0048 0090-0036,10.2105/AJPH.2011.300149,,"Complex systems approaches have received increasing attention in public health because reductionist approaches yield limited insights in the context of dynamic systems. Most discussions have been highly abstract. There is a need to consider the application of complex systems approaches to specific research questions. I review the features of population health problems for which complex systems approaches are most likely to yield new insights, and discuss possible applications of complex systems to health disparities research. I provide illustrative examples of how complex systems approaches may help address unanswered and persistent questions regarding genetic factors, life course processes, place effects, and the impact of upstream policies. The concepts and methods of complex systems may help researchers move beyond current impasse points in health disparities research.",2011-09,26/11/2018 12:52,14/04/2020 08:34,,1627-1634,,9,101,,Am J Public Health,,,,,,,,eng,,,,,,,PMID: 21778505 PMCID: PMC3154209,,,,Humans; Socioeconomic Factors; *Public Health; Environment; *Systems Theory; Health Surveys; *Health Status Disparities; 1; Genetic Predisposition to Disease; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TKMZ39GA,journalArticle,2011,"Anagnostou, Anastasia; Eatock, Julie; Taylor, Simon J. E.",Response to Forsberg et al (2011). Managing health care decisions and improvement through simulation modeling: modeling versus modelling.,Quality management in health care,,1550-5154 1063-8628,10.1097/QMH.0b013e318222a34d,,,2011-09,26/11/2018 12:52,14/04/2020 08:34,,246-247,,3,20,,Qual Manag Health Care,,,,,,,,eng,,,,,,,PMID: 21725222,,,,"Humans; *Computer Simulation; *Decision Making; Decision Support Systems, Clinical/*organization & administration; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Y2CN483E,journalArticle,2011,"Zhang, Yanlei; Kivipelto, Miia; Solomon, Alina; Wimo, Anders",Cost-effectiveness of a health intervention program with risk reductions for getting demented: results of a Markov model in a Swedish/Finnish setting.,Journal of Alzheimer's disease : JAD,,1875-8908 1387-2877,10.3233/JAD-2011-110065,,"Risk scores based on modifiable factors have recently been developed for dementia. This study aims to estimate the cost-effectiveness of a potential preventive intervention program meant to lower the score related to increased dementia risk. Analyses were based on a Markov model adapted to Swedish circumstances. Risk score categories and risk probabilities were derived from the Cardiovascular Risk Factors, Aging and Incidence of Dementia (CAIDE) study in Finland. Figures of costs, utilities, and mortality were obtained from literature or databases. One-way sensitivity analysis and probabilistic sensitivity analysis were carried out to investigate the robustness of the model and to identify which model inputs had most impact on the results. In the base case, the usual care had a cost of 621,000 SEK and utilities of 11.8438 quality-adjusted life year (QALYs). The intervention had a cost of 599, 026 SEK and utilities of 11.8950 QALYs. The cost was 21,974 SEK lower in the intervention with 0.0511 QALYs gained over a 20 years horizon, indicating absolute dominance. The support for cost-effectiveness was insensitive to changes in the value of QALY for demented, mortality, and risk of dementia. If the intervention program was assumed to run every year, the incremental cost-effectiveness ratio did not show absolute dominance but was still under the willingness-to-pay level. The probabilistic sensitivity analysis indicated cost effectiveness in 67% of the samplings given a willingness-to-pay level of 600,000 SEK/year. This is a promising outlook for future research on preventive interventions in dementia, emphasizing the need of conducting multi-domain randomized trials.",2011,26/11/2018 12:52,14/04/2020 08:35,,735-744,,4,26,,J Alzheimers Dis,,,,,,,,eng,,,,,,,PMID: 21709377,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Health Care Costs; Aged; Markov Chains; Risk Assessment; Monte Carlo Method; Models, Statistical; Risk Reduction Behavior; Data Interpretation, Statistical; Sweden/epidemiology; 00; Aging/psychology; Dementia/*economics/mortality/*prevention & control; Early Medical Intervention/*economics; Finland/epidemiology; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, X567CD6B,journalArticle,2011,"Barlow, James; Bayer, Steffen",Raising the profile of simulation and modelling in health services planning and implementation.,Journal of health services research & policy,,1758-1060 1355-8196,10.1258/jhsrp.2011.011018,,,2011-07,26/11/2018 12:52,14/04/2020 08:34,,129-130,,3,16,,J Health Serv Res Policy,,,,,,,,eng,,,,,,,PMID: 21708919,,,,"Humans; *Computer Simulation; Decision Making; *Models, Theoretical; Systems Integration; 00; Health Planning/*methods; ******To read; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6XEYNHSU,journalArticle,2011,"Lawton, Kitta; Binzer, Kristine; Skjoet, Peter; Jensen, Sanne",Lessons learnt from conducting a high fidelity simulation test in health IT.,Studies in health technology and informatics,,0926-9630 0926-9630,,,"Testing IT-systems by use of simulation requires a thorough planning and preparation in order to create a realistic clinical environment. For a successful test through simulation a dedicated test team to control the environment is needed, as well as people to play the role of patients and staff. Relevant artifacts and elaborate scenarios ensure the narrative. This paper explores the preliminary work and execution of an extensive test of a Computerized Order Entry System prototype. Central to the setup of the test is a script which outlines the method by guiding the preparation and execution.",2011,26/11/2018 12:52,14/04/2020 08:34,,217-226,,,166,,Stud Health Technol Inform,,,,,,,,eng,,,,,,,PMID: 21685627,,,,"Humans; *Computer Simulation; Decision Support Systems, Clinical/*organization & administration; Medical Order Entry Systems/*organization & administration; 00; Information Systems/organization & administration; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6A2VLPDR,journalArticle,2011,"Bishai, David; Johns, Benjamin; Nair, Divya; Nabyonga-Orem, Juliet; Fiona-Makmot, Braka; Simons, Emily; Dabbagh, Alya",The cost-effectiveness of supplementary immunization activities for measles: a stochastic model for Uganda.,The Journal of infectious diseases,,1537-6613 0022-1899,10.1093/infdis/jir131,,"Supplemental Immunization Activities (SIAs) have become an important adjunct to measles control efforts in countries that endeavor to achieve higher levels of population immunity than can be achieved in a growing routine immunization system. Because SIAs are often supported with funds that have alternative uses, decision makers need to know how cost-effective they are compared with other options. This study integrated a dynamic stochastic model of measles transmission in Uganda (2010-2050) with a cost model to compare a strategy of maintaining Uganda's current (2008) levels of the first dose of routine measles-containing vaccine (MCV1) coverage at 68% with SIAs with a strategy using the same levels of MCV1 coverage without SIAs. The stochastic model was fitted with parameters drawn from district-level measles case reports from Uganda, and the cost model was fitted to administrative data from the Ugandan Expanded Program on Immunization and from the literature. A discount rate of 0.03, time horizon of 2010-2050, and a societal perspective on costs were assumed. Costs expressed in US dollars (2010) included vaccination costs, disease treatment costs including lost productivity of mothers, as well as costs of outbreaks and surveillance. The model estimated that adding on triennial SIAs that covered 95% of children aged",2011-07,26/11/2018 12:52,14/04/2020 08:34,,S107-115,,,204 Suppl 1,,J Infect Dis,,,,,,,,eng,(c) The Author 2011. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved.,,,,,,PMID: 21666151 PMCID: PMC3690572,,,,"Humans; Cost-Benefit Analysis; *Models, Statistical; Child, Preschool; Infant; Models, Economic; Models, Biological; Stochastic Processes; 00; Uganda/epidemiology; Disease Outbreaks/economics/prevention & control/statistics & numerical data; Immunization Programs/*economics/methods/organization & administration; Measles Vaccine/administration & dosage/*economics; Measles/economics/*epidemiology/*prevention & control/transmission; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RL53I2V4,journalArticle,2011,"Laer, Stephanie",Pediatric cardiovascular drug development and research: integration of modeling and simulation as one future direction.,Journal of cardiovascular pharmacology,,1533-4023 0160-2446,10.1097/FJC.0b013e31822233c1,,"The integration of the needs of children into the legal drug development process since 1997 in the United States and since 2007 in the European Union has improved health and stimulated innovative approaches in the design of clinical trials and will benefit both current and future populations. According to the US Food and Drug Administration, to date, 394 pediatric labels together with safer medicines and better dosing practices have provided a sound basis for the safer and more effective use of drugs in a pediatric population. This may be measurable with fewer medication errors and perhaps shorter hospital stays in the future. Although relevant data have been generated by clinical trials in pediatric populations, challenges, such as nonefficacy and safety issues, have arisen. Heterogeneity in the physiological maturation and growth processes and differences in the etiology and pathogenesis of disease in patients from birth to 18 years of age may explain these results. The use of cutting-edge technology, such as modeling and simulation of ""in silico"" pediatric populations, may allow the integration of data from previous trials and experiments into the design of future clinical trials and allow exploration in other areas that have the potential to enhance the outcome of clinical trials in children.",2011-09,26/11/2018 12:52,14/04/2020 08:34,,217-227,,3,58,,J Cardiovasc Pharmacol,,,,,,,,eng,,,,,,,PMID: 21654330,,,,"European Union; Humans; United States; Female; Male; Child; Adolescent; Computer Simulation; Child, Preschool; *Pediatrics; Models, Biological; 00; *Cardiovascular Agents/adverse effects/metabolism/pharmacokinetics/therapeutic use; *Drug Industry/legislation & jurisprudence/methods; Drug Discovery/*methods; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5Q8PIM57,journalArticle,2011,"Siassakos, Dimitrios; Bristowe, Katherine; Hambly, Helen; Angouri, Jo; Crofts, Joanna F.; Winter, Catherine; Hunt, Linda P.; Draycott, Timothy J.",Team communication with patient actors: findings from a multisite simulation study.,Simulation in healthcare : journal of the Society for Simulation in Healthcare,,1559-713X 1559-2332,10.1097/SIH.0b013e31821687cf,,"INTRODUCTION: Patient satisfaction is an important healthcare outcome and communication with clinical staff is an important determinant. Simulation could identify problems and inform corrective action to improve patient experience. METHODS: One hundred eight randomly selected maternity professionals in 18 teams were videoed managing a patient-actor with a simulated emergency. The trained patient-actor assessed the quality of staff-patient interaction. Clinicians scored teams for their teamwork skills and behaviors. RESULTS: There was significant variation in staff-patient interaction, with some teams not having exchanged a single word and others striving to interact with the patient-actor in the heat of the emergency. There was significant correlation between patient-actor perceptions of communication, respect, and safety and individual and team behaviors: number, duration, and content of communication episodes, as well as generic teamwork skills and teamwork behaviors. The patient-actor perception of safety was better when the content of the communication episodes with them included certain items of information, but most teams failed to communicate these to the patient-actor. CONCLUSION: Some aspects of staff-patient interaction and teamwork during management of a simulated emergency varied significantly and were often inadequate in this study, indicating a need for better training of individuals and teams.",2011-06,26/11/2018 12:52,14/04/2020 08:35,,143-149,,3,6,,Simul Healthc,,,,,,,,eng,,,,,,,PMID: 21646983,,,,"Humans; Patient Satisfaction; Clinical Competence; *Patient Simulation; Emergencies; *Communication; Patient Care Team/*organization & administration; Cross-Sectional Studies; Attitude of Health Personnel; Inservice Training/*methods; Professional-Patient Relations; 00; Obstetrics and Gynecology Department, Hospital/*organization & administration; Safety Management/organization & administration; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EXXII55F,journalArticle,2011,"Zhang, Fang; Wagner, Anita K.; Ross-Degnan, Dennis",Simulation-based power calculation for designing interrupted time series analyses of health policy interventions.,Journal of clinical epidemiology,,1878-5921 0895-4356,10.1016/j.jclinepi.2011.02.007,,"OBJECTIVE: Interrupted time series is a strong quasi-experimental research design to evaluate the impacts of health policy interventions. Using simulation methods, we estimated the power requirements for interrupted time series studies under various scenarios. STUDY DESIGN AND SETTING: Simulations were conducted to estimate the power of segmented autoregressive (AR) error models when autocorrelation ranged from -0.9 to 0.9 and effect size was 0.5, 1.0, and 2.0, investigating balanced and unbalanced numbers of time periods before and after an intervention. Simple scenarios of autoregressive conditional heteroskedasticity (ARCH) models were also explored. RESULTS: For AR models, power increased when sample size or effect size increased, and tended to decrease when autocorrelation increased. Compared with a balanced number of study periods before and after an intervention, designs with unbalanced numbers of periods had less power, although that was not the case for ARCH models. CONCLUSION: The power to detect effect size 1.0 appeared to be reasonable for many practical applications with a moderate or large number of time points in the study equally divided around the intervention. Investigators should be cautious when the expected effect size is small or the number of time points is small. We recommend conducting various simulations before investigation.",2011-11,26/11/2018 12:52,14/04/2020 08:35,,1252-1261,,11,64,,J Clin Epidemiol,,,,,,,,eng,Copyright (c) 2011 Elsevier Inc. All rights reserved.,,,,,,PMID: 21640554,,,,"*Health Policy; Humans; *Models, Statistical; Research Design; Time Factors; Policy Making; Regression Analysis; Sample Size; 00; *Evaluation Studies as Topic; ******To read; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, G8P3AVVX,journalArticle,2011,"Crasto, W.; Jarvis, J.; Khunti, K.; Skinner, T. C.; Gray, L. J.; Brela, J.; Troughton, J.; Daly, H.; Lawrence, I. G.; McNally, P. G.; Carey, M. E.; Davies, M. J.",Multifactorial intervention in individuals with type 2 diabetes and microalbuminuria: the Microalbuminuria Education and Medication Optimisation (MEMO) study.,Diabetes research and clinical practice,,1872-8227 0168-8227,10.1016/j.diabres.2011.05.008,,"AIMS: To determine whether tighter cardiovascular risk factor control with structured education in individuals with type 2 diabetes (T2DM) and microalbuminuria benefits cardiovascular risk factors. METHODS: Participants from a multiethnic population, recruited from primary care and specialist clinics were randomised to intensive intervention with structured patient (DESMOND model) education (n=94) or usual care by own health professional (n=95). PRIMARY OUTCOME: change in HbA1c at 18months. SECONDARY OUTCOMES: changes in blood pressure (BP), cholesterol, albuminuria, proportion reaching risk factor targets, modelled cardiovascular risk scores. RESULTS: Mean (SD) age and diabetes duration of participants were 61.5 (10.5) and 11.5 (9.3) years, respectively. At 18months, intensive intervention showed significant improvements in HbA1c (7.1(1.0) vs. 7.8(1.4)%, p<0.0001), systolic BP (129(16) vs. 139(17) mmHg, p<0.0001), diastolic BP (70(11) vs. 76(12) mmHg, p<0.001), total cholesterol (3.7(0.8) vs. 4.1(0.9) mmol/l, p=0.001). Moderate and severe hypoglycaemia was 11.2 vs. 29.0%; p=0.001 and 0 vs. 6.3%; p=0.07, respectively. More intensive participants achieved >/=3 risk factor targets with greater reductions in cardiovascular risk scores. CONCLUSIONS: Intensive intervention showed greater improvements in metabolic control and cardiovascular risk profile with lower rates of moderate and severe hypoglycaemia. Intensive glycaemic interventions should be underpinned by structured education promoting self-management in T2DM.",2011-09,26/11/2018 12:52,14/04/2020 08:34,,328-336,,3,93,,Diabetes Res Clin Pract,,,,,,,,eng,Copyright (c) 2011 Elsevier Ireland Ltd. All rights reserved.,,,,,,PMID: 21640424,,,,"Humans; Adult; Female; Male; Middle Aged; Risk Factors; Aged; Aged, 80 and over; Blood Pressure/drug effects; 00; Glycated Hemoglobin A/metabolism; Albuminuria/blood/*drug therapy/*urine; Antihypertensive Agents/therapeutic use; Aspirin/therapeutic use; Cholesterol/blood; Diabetes Mellitus, Type 2/blood/*drug therapy/*urine; Hypoglycemia/blood/drug therapy/urine; Hypoglycemic Agents/therapeutic use; Hypolipidemic Agents/therapeutic use; Insulin/therapeutic use; Metformin/therapeutic use; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NJF9JD2A,journalArticle,2011,"Hayes, Alison J.; Clarke, Philip M.; Voysey, Merryn; Keech, Anthony",Simulation of quality-adjusted survival in chronic diseases: an application in type 2 diabetes.,Medical decision making : an international journal of the Society for Medical Decision Making,,1552-681X 0272-989X,10.1177/0272989X11409049,,"BACKGROUND: Recent studies have demonstrated that measures of health-related quality of life can predict complications and mortality in patients with diabetes, even after adjustment for clinical risk factors. METHODS: The authors developed a simulation model of disease progression in type 2 diabetes to investigate the impact of patient quality of life on lifetime outcomes and its potential response to therapy. Changes in health utility over time are captured as a result of complications and aging. All risk equations, model parameter estimates, and input data were derived from patient-level data from the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) trial. RESULTS: Healthier patients with type 2 diabetes enjoy more life years, quality-adjusted life years (QALYs), and more life years free of complications. A 65-year-old patient at full health (utility = 1) can expect to live approximately 2 years longer and achieve 6 more QALYs than a patient at average health (utility = 0.8), given similar clinical risk factors. For patients with higher EQ-5D utility, the additional years lived without complications contribute more to longer life expectancy than years lived with complications. CONCLUSIONS: The authors have developed a model for progression of disease in diabetes that has a number of novel features; it captures the observed relationships between measures of quality of life and future outcomes, the number of states have been minimized, and it can be parameterized with just 4 risk equations. Underlying the simple model structure is important patient-level heterogeneity in health and outcomes. The simulations suggest that differences in patients' EQ-5D utility can account for large differences in QALYs, which could be relevant in cost-utility analyses.",2011-08,26/11/2018 12:52,14/04/2020 08:34,,559-570,,4,31,,Med Decis Making,,,,,,,,eng,,,,,,,PMID: 21636740,,,,"Humans; Female; Male; Middle Aged; *Quality-Adjusted Life Years; Aged; Chronic Disease; Health Status; *Survival Analysis; 1; Diabetes Mellitus, Type 2/*physiopathology; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, AFWQUETJ,journalArticle,2011,"Brown, Shawn T.; Tai, Julie H. Y.; Bailey, Rachel R.; Cooley, Philip C.; Wheaton, William D.; Potter, Margaret A.; Voorhees, Ronald E.; LeJeune, Megan; Grefenstette, John J.; Burke, Donald S.; McGlone, Sarah M.; Lee, Bruce Y.",Would school closure for the 2009 H1N1 influenza epidemic have been worth the cost?: a computational simulation of Pennsylvania.,BMC public health,,1471-2458 1471-2458,10.1186/1471-2458-11-353,,"BACKGROUND: During the 2009 H1N1 influenza epidemic, policy makers debated over whether, when, and how long to close schools. While closing schools could have reduced influenza transmission thereby preventing cases, deaths, and health care costs, it may also have incurred substantial costs from increased childcare needs and lost productivity by teachers and other school employees. METHODS: A combination of agent-based and Monte Carlo economic simulation modeling was used to determine the cost-benefit of closing schools (vs. not closing schools) for different durations (range: 1 to 8 weeks) and symptomatic case incidence triggers (range: 1 to 30) for the state of Pennsylvania during the 2009 H1N1 epidemic. Different scenarios varied the basic reproductive rate (R(0)) from 1.2, 1.6, to 2.0 and used case-hospitalization and case-fatality rates from the 2009 epidemic. Additional analyses determined the cost per influenza case averted of implementing school closure. RESULTS: For all scenarios explored, closing schools resulted in substantially higher net costs than not closing schools. For R(0) = 1.2, 1.6, and 2.0 epidemics, closing schools for 8 weeks would have resulted in median net costs of $21.0 billion (95% Range: $8.0 - $45.3 billion). The median cost per influenza case averted would have been $14,185 ($5,423 - $30,565) for R(0) = 1.2, $25,253 ($9,501 - $53,461) for R(0) = 1.6, and $23,483 ($8,870 - $50,926) for R(0) = 2.0. CONCLUSIONS: Our study suggests that closing schools during the 2009 H1N1 epidemic could have resulted in substantial costs to society as the potential costs of lost productivity and childcare could have far outweighed the cost savings in preventing influenza cases.",20/05/2011,26/11/2018 12:52,14/04/2020 08:34,,353,,,11,,BMC Public Health,,,,,,,,eng,,,,,,,PMID: 21599920 PMCID: PMC3119163,,,,"Humans; Adult; Middle Aged; Young Adult; Aged; Child; Adolescent; Monte Carlo Method; Models, Statistical; Child, Preschool; Infant; Models, Econometric; Disease Outbreaks/*prevention & control; 00; *Influenza A Virus, H1N1 Subtype; Influenza, Human/economics/*epidemiology/prevention & control; Pennsylvania/epidemiology; Schools/*economics; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CHDKY2VJ,journalArticle,2011,"Jun, Gyuchan T.; Morris, Zoe; Eldabi, Tillal; Harper, Paul; Naseer, Aisha; Patel, Brijesh; Clarkson, John P.",Development of modelling method selection tool for health services management: from problem structuring methods to modelling and simulation methods.,BMC health services research,,1472-6963 1472-6963,10.1186/1472-6963-11-108,,"BACKGROUND: There is an increasing recognition that modelling and simulation can assist in the process of designing health care policies, strategies and operations. However, the current use is limited and answers to questions such as what methods to use and when remain somewhat underdeveloped. AIM: The aim of this study is to provide a mechanism for decision makers in health services planning and management to compare a broad range of modelling and simulation methods so that they can better select and use them or better commission relevant modelling and simulation work. METHODS: This paper proposes a modelling and simulation method comparison and selection tool developed from a comprehensive literature review, the research team's extensive expertise and inputs from potential users. Twenty-eight different methods were identified, characterised by their relevance to different application areas, project life cycle stages, types of output and levels of insight, and four input resources required (time, money, knowledge and data). RESULTS: The characterisation is presented in matrix forms to allow quick comparison and selection. This paper also highlights significant knowledge gaps in the existing literature when assessing the applicability of particular approaches to health services management, where modelling and simulation skills are scarce let alone money and time. CONCLUSIONS: A modelling and simulation method comparison and selection tool is developed to assist with the selection of methods appropriate to supporting specific decision making processes. In particular it addresses the issue of which method is most appropriate to which specific health services management problem, what the user might expect to be obtained from the method, and what is required to use the method. In summary, we believe the tool adds value to the scarce existing literature on methods comparison and selection.",19/05/2011,26/11/2018 12:52,14/04/2020 08:34,,108,,,11,,BMC Health Serv Res,,,,,,,,eng,,,,,,,PMID: 21595946 PMCID: PMC3130639,,,,"Humans; Qualitative Research; *Computer Simulation; United Kingdom; Evidence-Based Practice; Health Services Accessibility/*organization & administration; Models, Organizational; Education; *Decision Making; 1; *Health Services; *Health Services Administration; Health Services Research/methods/*organization & administration; Knowledge; ******To read; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ILRPWELF,journalArticle,2011,"Asokan, G. V.; Asokan, Vanitha; Fedorowicz, Zbys; Tharyan, Prathap",Use of a systems approach and evidence-based One Health for zoonoses research.,Journal of evidence-based medicine,,1756-5391 1756-5391,10.1111/j.1756-5391.2011.01124.x,,"The World Health Organization estimates that 25% of the 57 million annual deaths that occur globally are caused by microbes. A study reported 1415 species of infectious organisms are known to be pathogenic to humans. Zoonoses constitute 61% of all known infectious diseases, with humans serving as the primary reservoir for only 3% of them. Of the 175 infectious species considered to be emerging, 75% are zoonotic. Zoonotic diseases and their impact on human and animal health are not monitored, prevented, and treated in an integrated way, despite the fact that etiologies and treatments are similar across species. The efficacy and resistance of a drug in one species has a bearing on others, in the context of zoonoses. Further, an RCT involving many species is effective in a natural setting, is robust, and may require fewer human volunteers. One Health is based on a systems approach and a collaborative effort of multiple disciplines - working locally, nationally, and globally - to attain optimal health for people, animals, and the environment. Systematic reviews and meta-analyses have so far been independent and discipline oriented. Pooling of results for diagnostic test accuracies and treatment effects of drugs for zoonoses across species has to be done, since the results of preclinical trials emanate from laboratory animals. The Cochrane Collaboration is the platform of choice to initiate a new group on zoonoses to carry out systematic meta-analyses of diagnostic tests and drug efficacies without bias, thus underpinning the systems approach and One Health.",2011-05,26/11/2018 12:52,14/04/2020 08:34,,62-65,,2,4,,J Evid Based Med,,,,,,,,eng,"(c) 2011 Blackwell Publishing Asia Pty Ltd and Chinese Cochrane Center, West China Hospital of Sichuan University.",,,,,,PMID: 23672696,,,,Humans; Animals; Biomedical Research/*methods; *Evidence-Based Medicine; 00; *Zoonoses; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HP6HIBX6,journalArticle,2010,"Hamman, William R.; Beaudin-Seiler, Beth M.; Beaubien, Jeffrey M.",Understanding interdisciplinary health care teams: using simulation design processes from the Air Carrier Advanced Qualification Program to identify and train critical teamwork skills.,Journal of patient safety,,1549-8425 1549-8417,,,"In the report ""Five Years After 'To Err is Human' "", it was noted that ""the combination of complexity, professional fragmentation, and a tradition of individualism, enhanced by a well-entrenched hierarchical authority structure and diffuse accountability, forms a daunting barrier to creating the habits and beliefs of common purpose, teamwork, and individual accountability for successful interdependence that a safe culture requires"". Training physicians, nurses, and other professionals to work in teams is a concept that has been promoted by many patient safety experts. However the model of teamwork in healthcare is diffusely defined, no clear performance metrics have been established, and the use of simulation to train teams has been suboptimal. This paper reports on the first three years of work performed in the Michigan Economic Development Corporation (MEDC) Tri-Corridor life science grant to apply concepts and processes of simulation design that were developed in the air carrier industry to understand and train healthcare teams. This work has been monitored by the American Academy for the Advancement of Science (AAA) and is based on concepts designed in the Advanced Qualification Program (AQP) from the air carrier industry, which trains and assesses teamwork skills in the same manner as technical skills. This grant has formed the foundation for the Center of Excellence for Simulation Education and Research (CESR).",2010-09,26/11/2018 12:52,14/04/2020 08:34,,137-146,,3,6,,J Patient Saf,,,,,,,,eng,,,,,,,PMID: 21491786,,,,Humans; Medical Errors/prevention & control; Reproducibility of Results; *Clinical Competence; Patient Care Team/*organization & administration; *Interdisciplinary Communication; Organizational Culture; Michigan; 00; Safety Management; Teaching/methods; *Certification; Program Development/*methods; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4GWBUETD,journalArticle,2011,"Abraham, Justin; Wade, Dina M.; O'Connell, Katherine A.; Desharnais, Susan; Jacoby, Richard",The use of simulation training in teaching health care quality and safety: an annotated bibliography.,American journal of medical quality : the official journal of the American College of Medical Quality,,1555-824X 1062-8606,10.1177/1062860610384716,,,2011-06,26/11/2018 12:52,14/04/2020 08:34,,229-238,,3,26,,Am J Med Qual,,,,,,,,eng,,,,,,,PMID: 21490271,,,,"Humans; Quality Assurance, Health Care/*methods; Health Personnel/*education; *Safety Management; Inservice Training/*methods; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BXFLRNU9,journalArticle,2011,"Cowie, Martin R.; Cure, Sandrine; Bianic, Florence; McGuire, Alistair; Goodall, Gordon; Tavazzi, Luigi",Cost-effectiveness of highly purified omega-3 polyunsaturated fatty acid ethyl esters in the treatment of chronic heart failure: results of Markov modelling in a UK setting.,European journal of heart failure,,1879-0844 1388-9842,10.1093/eurjhf/hfr023,,"AIMS: A recent randomized placebo-controlled clinical trial has reported reductions in mortality and hospitalizations in patients with chronic heart failure (CHF) who were prescribed highly purified omega-3 polyunsaturated fatty acid ethyl esters (n-3 PUFA). This study aimed at evaluating the cost and benefits associated with their use in the treatment of CHF in a UK setting. METHODS AND RESULTS: Results from a recent clinical trial were used to develop a Markov model to project clinical outcomes while capturing relevant costs and patient quality of life. The model captured outcomes over a lifetime horizon from a UK National Health Service perspective, with direct costs accounted in 2009 GBP ( pound) and discounted at 3.5% together with clinical benefits. Results are presented in terms of life expectancy, quality-adjusted life expectancy, direct costs, and incremental cost-effectiveness ratios. In addition to standard therapy, n-3 PUFA vs. placebo increased lifetime direct costs by pound993 ( approximately euro1150), with additional quality-adjusted life expectancy of 0.079 quality-adjusted life years (QALYs), and mean lifetime costs of pound12,636 ( approximately euro14,600) per QALY gained. Probabilistic sensitivity analyses suggested a 60% likelihood of n-3 PUFA being regarded as cost-effective versus placebo at a willingness-to-pay threshold of pound30,000 ( approximately euro34,600) per QALY gained. CONCLUSIONS: By currently accepted standards of value for money in the UK; the addition of n-3 PUFA to optimal medical therapy for patients with heart failure is likely to be cost-effective.",2011-06,26/11/2018 12:52,14/04/2020 08:34,,681-689,,6,13,,Eur J Heart Fail,,,,,,,,eng,,,,,,,PMID: 21474462,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Treatment Outcome; Female; Male; Aged; *Computer Simulation; Chronic Disease; United Kingdom; Sensitivity and Specificity; State Medicine; 00; Fatty Acids, Omega-3/*therapeutic use; Heart Failure/*drug therapy/economics; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IR492M67,journalArticle,2011,"Anderson, Benjamin O.; Cazap, Eduardo; El Saghir, Nagi S.; Yip, Cheng-Har; Khaled, Hussein M.; Otero, Isabel V.; Adebamowo, Clement A.; Badwe, Rajendra A.; Harford, Joe B.","Optimisation of breast cancer management in low-resource and middle-resource countries: executive summary of the Breast Health Global Initiative consensus, 2010.",The Lancet. Oncology,,1474-5488 1470-2045,10.1016/S1470-2045(11)70031-6,,"The purpose of the Breast Health Global Initiative (BHGI) 2010 summit was to provide a consensus analysis of breast cancer control issues and implementation strategies for low-income and middle-income countries (LMCs), where advanced stages at presentation and poor diagnostic and treatment capacities contribute to lower breast cancer survival rates than in high-income countries. Health system and patient-related barriers were identified that create common clinical scenarios in which women do not present for diagnosis until their cancer has progressed to locally advanced or metastatic stages. As countries progress to higher economic status, the rate of late presentation is expected to decrease, and diagnostic and treatment resources are expected to improve. Health-care systems in LMCs share many challenges including national or regional data collection, programme infrastructure and capacity (including appropriate equipment and drug acquisitions, and professional training and accreditation), the need for qualitative and quantitative research to support decision making, and strategies to improve patient access and compliance as well as public, health-care professional, and policy-maker awareness that breast cancer is a cost-effective, treatable disease. The biggest challenges identified for low-income countries were little community awareness that breast cancer is treatable, inadequate advanced pathology services for diagnosis and staging, and fragmented treatment options, especially for the administration of radiotherapy and the full range of systemic treatments. The biggest challenges identified for middle-resource countries were the establishment and maintenance of data registries, the coordination of multidisciplinary centres of excellence with broad outreach programmes to provide community access to cancer diagnosis and treatment, and the resource-appropriate prioritisation of breast cancer control programmes within the framework of existing, functional health-care systems.",2011-04,26/11/2018 12:52,14/04/2020 08:34,,387-398,,4,12,,Lancet Oncol,,,,,,,,eng,Copyright (c) 2011 Elsevier Ltd. All rights reserved.,,,,,,PMID: 21463833,,,,Humans; Delivery of Health Care; Female; Cost of Illness; Developing Countries; Patient Advocacy; 00; Consensus; Breast Neoplasms/diagnosis/mortality/*therapy; Early Detection of Cancer; 100; 120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NLWYMGNX,journalArticle,2011,"Rutter, Carolyn M.; Knudsen, Amy B.; Pandharipande, Pari V.",Computer disease simulation models: integrating evidence for health policy.,Academic radiology,,1878-4046 1076-6332,10.1016/j.acra.2011.02.004,,"Computer disease simulation models are increasingly being used to evaluate and inform health care decisions across medical disciplines. The aim of researchers who develop these models is to integrate and synthesize short-term outcomes and results from multiple sources to predict the long-term clinical outcomes and costs of different health care strategies. Policy makers, in turn, can use the predictions generated by disease models together with other evidence to make decisions related to health care practices and resource utilization. Models are particularly useful when the existing evidence does not yield obvious answers or does not provide answers to the questions of greatest interest, such as questions about the relative cost-effectiveness of different practices. This review focuses on models used to inform decisions about imaging technology, discussing the role of disease models for health policy development and providing a foundation for understanding the basic principles of disease modeling. This manuscript draws from the collective computed tomographic colonography modeling experience, reviewing 10 published investigations of the clinical effectiveness and cost-effectiveness of computed tomographic colonography relative to colonoscopy. The discussion focuses on implications of different modeling assumptions and difficulties that may be encountered when evaluating the quality of models. This underscores the importance of forging stronger collaborations between researchers who develop disease models and radiologists, to ensure that policy-level models accurately represent the experience of everyday clinical practices.",2011-09,26/11/2018 12:52,14/04/2020 08:35,,1077-1086,,9,18,,Acad Radiol,,,,,,,,eng,Copyright (c) 2011 AUR. Published by Elsevier Inc. All rights reserved.,,,,,,PMID: 21435924 PMCID: PMC3125421,,,,"*Health Policy; Humans; Cost-Benefit Analysis; Health Care Costs; *Computer Simulation; Decision Making; Quality Assurance, Health Care; *Evidence-Based Medicine; 1; Colonography, Computed Tomographic/*economics; Colorectal Neoplasms/*diagnostic imaging/*economics; ******To read; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5Q6Y8LV7,journalArticle,2011,"Nerenz, David R.; Liu, Yung-wen; Williams, Keoki L.; Tunceli, Kaan; Zeng, Huiwen",A simulation model approach to analysis of the business case for eliminating health care disparities.,BMC medical research methodology,,1471-2288 1471-2288,10.1186/1471-2288-11-31,,"BACKGROUND: Purchasers can play an important role in eliminating racial and ethnic disparities in health care. A need exists to develop a compelling ""business case"" from the employer perspective to put, and keep, the issue of racial/ethnic disparities in health care on the quality improvement agenda for health plans and providers. METHODS: To illustrate a method for calculating an employer business case for disparity reduction and to compare the business case in two clinical areas, we conducted analyses of the direct (medical care costs paid by employers) and indirect (absenteeism, productivity) effects of eliminating known racial/ethnic disparities in mammography screening and appropriate medication use for patients with asthma. We used Markov simulation models to estimate the consequences, for defined populations of African-American employees or health plan members, of a 10% increase in HEDIS mammography rates or a 10% increase in appropriate medication use among either adults or children/adolescents with asthma. RESULTS: The savings per employed African-American woman aged 50-65 associated with a 10% increase in HEDIS mammography rate, from direct medical expenses and indirect costs (absenteeism, productivity) combined, was $50. The findings for asthma were more favorable from an employer point of view at approximately $1,660 per person if raising medication adherence rates in African-American employees or dependents by 10%. CONCLUSIONS: For the employer business case, both clinical scenarios modeled showed positive results. There is a greater potential financial gain related to eliminating a disparity in asthma medications than there is for eliminating a disparity in mammography rates.",19/03/2011,26/11/2018 12:52,14/04/2020 08:35,,31,,,11,,BMC Med Res Methodol,,,,,,,,eng,(c) 2011 Nerenz et al; licensee BioMed Central Ltd.,,,,,,PMID: 21418594 PMCID: PMC3073955,,,,"Humans; Health Services Accessibility; Health Services Research; Quality of Health Care; Quality-Adjusted Life Years; Adult; Female; Middle Aged; Young Adult; Aged; Child; Adolescent; Computer Simulation; Models, Theoretical; Life Expectancy; 1; Absenteeism; African Americans; *Employer Health Costs; Asthma/drug therapy/economics; Breast Neoplasms/economics; Healthcare Disparities/*economics; Mammography/economics; Prepaid Health Plans; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, L4VT9HXH,journalArticle,2011,"Dedhia, Raj C.; Smith, Kenneth J.; Johnson, Jonas T.; Roberts, Mark",The cost-effectiveness of community-based screening for oral cancer in high-risk males in the United States: a Markov decision analysis approach.,The Laryngoscope,,1531-4995 0023-852X,10.1002/lary.21412,,"OBJECTIVE: The 2004 US Preventative Services Task Force (USPSTF) guidelines do not recommend routinely screening adults for oral cancer given no proven mortality reduction. A large cluster-randomized controlled screening trial in Kerala, India, in 2005, however, reported a significant reduction in mortality for screened male tobacco and/or alcohol users. In the United States, office-based screening efforts targeting males of high risk (regular use of tobacco and/or alcohol) have been unsuccessful due to poor attendance. Given the newfound screening mortality benefit to this high-risk subpopulation, we sought to ascertain the cost-effectiveness threshold of a yearly, community outreach screening program for males more than 40 years regularly using tobacco and/or alcohol. STUDY DESIGN: Markov decision analysis model; societal perspective. METHODS: A literature search was performed to determine event probabilities, health utilities, and cost parameters to serve as model inputs. Screen versus No-Screen strategies were modeled using assumptions and published data. The primary outcome was the difference in costs and quality-adjusted life-years (QALYs) between the two cohorts, representing the potential budget for a screening program. One-way sensitivity analysis was performed for several key parameters. RESULTS: The No-Screen arm was dominated with an incremental cost of $258 and an incremental effectiveness of -0.0414 QALYs. Using the $75,000/QALY metric, the maximum allowable budget for a screening program equals $3,363 ($258 + $3,105) per screened person over a 40-year time course. CONCLUSION: Given the significant health benefits and financial savings via early detection in the screened cohort, a community-based screening program targeting high-risk males is likely to be cost-effective.",2011-05,26/11/2018 12:52,14/04/2020 08:34,,952-960,,5,121,,Laryngoscope,,,,,,,,eng,"Copyright &© 2011 The American Laryngological, Rhinological, and Otological Society, Inc.",,,,,,PMID: 21384383 PMCID: PMC3082601,,,,Humans; Cost-Benefit Analysis; Adult; Male; Risk Factors; Markov Chains; United States/epidemiology; Mass Screening/*economics; 00; Community Health Services/*economics; Mouth Neoplasms/*diagnosis/epidemiology; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, P6WV4XNS,journalArticle,2011,"Best, Allan",Systems thinking and health promotion.,American journal of health promotion : AJHP,,2168-6602 0890-1171,10.4278/ajhp.25.4.eix,,"The launch of the American Journal of Health Promotion blessed the field with a broad conceptual framework, now refined to include physical, emotional, social, spiritual, and intellectual dimensions of health.1 Throughout the years, this framework has become increasingly nuanced as research and practice have woven the rich fabric of what we know as health promotion today.",2011-04,26/11/2018 12:52,14/04/2020 08:34,,eix-ex,,4,25,,Am J Health Promot,,,,,,,,eng,,,,,,,PMID: 21361801,,,,Humans; *Systems Theory; Interinstitutional Relations; 1; Health Promotion/methods/*organization & administration; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CJ3PTCHX,journalArticle,2011,"Schneider, John A.; Laumann, Edward O.",Alternative explanations for negative findings in the community popular opinion leader multisite trial and recommendations for improvements of health interventions through social network analysis.,Journal of acquired immune deficiency syndromes (1999),,1944-7884 1525-4135,10.1097/QAI.0b013e318207a34c,,,2011-04,26/11/2018 12:52,14/04/2020 08:35,,e119-120,,4,56,,J Acquir Immune Defic Syndr,,,,,,,,eng,,,,,,,PMID: 21350361,,,,"Humans; Incidence; *Social Support; Disease Transmission, Infectious/prevention & control; HIV Infections/epidemiology/prevention & control/*psychology/*transmission; Sexual Behavior/*psychology/statistics & numerical data; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, B2AMP9J8,journalArticle,2010,"Nickman, Nancy A.; Haak, Sandra W.; Kim, Jaewhan",Use of clinical simulation centers in health professions schools for patient-centered research.,Simulation in healthcare : journal of the Society for Simulation in Healthcare,,1559-713X 1559-2332,10.1097/SIH.0b013e3181e91067,,"INTRODUCTION: Professional practice assessment research performed in clinical simulation centers is a research method that also creates opportunity for multidisciplinary investigator collaboration. METHODS: Nursing and pharmacy school clinical simulation laboratories at the University of Utah were used to conduct time-and-motion (TM) studies of medication dispensing and administration. Time data were then used to determine personnel and supply costs associated with different medication dosage forms and delivery methods. A case study from a completed research project describes the use of TM and activity-based costing analyses to assess medication preparation and administration time and cost differences related to three proton pump inhibitor dosage forms. Standardized doses were prepared by pharmacists or technicians and subsequently administered by nurses to a mannequin in the simulation center by seven different administration scenarios. Simulation scenarios were developed in a manner that held the independent variables constant, so that time and cost differences between dosage forms and administrations methods could be quantified. RESULTS: A detailed example of one approach to use of simulation centers for TM studies and activity-based costing analyses is provided. The advantages of isolating processes of interest from the day-to-day complexity of patient care are shown. Results illustrate how simulations based on professional school simulation centers may be used to assess health care processes at the microlevel with potential for projection to the macrolevel. CONCLUSIONS: Studies based on health professional schools simulation centers may offer a novel method of evaluating health care processes at the microlevel.",2010-10,26/11/2018 12:52,14/04/2020 08:35,,295-302,,5,5,,Simul Healthc,,,,,,,,eng,,,,,,,PMID: 21330812,,,,"Humans; Curriculum; Educational Status; Health Services Research/*methods; Cooperative Behavior; *Manikins; Videotape Recording; Time and Motion Studies; 00; Students, Nursing; *Schools, Nursing; *Schools, Pharmacy; Patient-Centered Care/*methods; Pharmaceutical Preparations/*administration & dosage; Proton Pump Inhibitors/administration & dosage/therapeutic use; Students, Pharmacy; Utah; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LU25XQTP,journalArticle,2011,"Ohno, Yoichi; Shibazaki, Satomi; Araki, Ryuichiro; Miyazaki, Takashi; Hanyu, Mayuko; Satoh, Makiko; Takenaka, Tsuneo; Okada, Hirokazu; Suzuki, Hiromichi",Antihypertensive medication versus health promotion for improving metabolic syndrome in preventing cardiovascular events: a success rate-oriented simulation study.,BMC medical informatics and decision making,,1472-6947 1472-6947,10.1186/1472-6947-11-8,,"BACKGROUND: In practice, it is difficult to compare the effectiveness of traditional antihypertensive treatment with that of health promotion in reducing incidence rate of cardiovascular disease (IRCVD, events/year). This simulation study compared the effectiveness of two approaches to reducing IRCVD in a sample population: a traditional approach, in which high-risk patients are treated with conventional antihypertensive medications, and a population-based approach, in which subjects participate in a health promotion program. METHODS: We constructed a simulation model for a sample population of middle-aged Japanese men whose systolic blood pressure (SBP) levels are normally distributed (130 +/- 20 mm Hg). The principal assumption was that IRCVD increases exponentially according to SBP. The population IRCVD was calculated as the product of the distribution of SBP multiplied by IRCVD at each SBP. The cumulative IRCVD was calculated by the definite integral from the lowest to the highest SBP of IRCVD at each SBP level. The success rates were calculated according to SBP and metabolic risk profiles in the two approaches, respectively. RESULTS: The reduction in IRCVD was twice as large for antihypertensive medications as it was for health promotion in several situations. For example, if adherence to antihypertensive treatment occurred at a realistic level, the decrease in IRCVD was estimated at 9.99 x 10(-4). In contrast, even if the health program was promoted optimistically, the decrease in IRCVD was estimated at 4.69 x 10(-4). CONCLUSIONS: The success rate-oriented simulation suggests that prescribing antihypertensive medications is superior to promoting the health promotion program in reducing IRCVD in virtual middle-aged Japanese men.",13/02/2011,26/11/2018 12:52,14/04/2020 08:35,,8,,,11,,BMC Med Inform Decis Mak,,,,,,,,eng,,,,,,,PMID: 21314988 PMCID: PMC3045871,,,,Humans; Treatment Outcome; Risk Factors; Computer Simulation; *Health Promotion; 1; Antihypertensive Agents/pharmacology/*therapeutic use; Cardiovascular Diseases/epidemiology/etiology/*prevention & control; Hypertension/complications/*drug therapy; Metabolic Syndrome/*complications/drug therapy; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8EBGCPZI,journalArticle,2011,"Chen, Ruth P.",Moral imagination in simulation-based communication skills training.,Nursing ethics,,1477-0989 0969-7330,10.1177/0969733010386163,,"Clinical simulation is used in nursing education and in other health professional programs to prepare students for future clinical practice. Simulation can be used to teach students communication skills and how to deliver bad news to patients and families. However, skilled communication in clinical practice requires students to move beyond simply learning superficial communication techniques and behaviors. This article presents an unexplored concept in the simulation literature: the exercise of moral imagination by the health professional student. Drawing from the works of Hume, Aristotle and Gadamer, a conceptualization of moral imagination is first provided. Next, this article argues that students must exercise moral imagination on two levels: towards the direct communication exchange before them; and to the representative nature of simulation encounters. Last, the limits of moral imagination in simulation-based education are discussed.",2011-01,26/11/2018 12:52,14/04/2020 08:34,,102-111,,1,18,,Nurs Ethics,,,,,,,,eng,,,,,,,PMID: 21285201,,,,"Humans; *Patient Simulation; Curriculum; *Communication; Education, Nursing, Baccalaureate/*methods; 00; *Morals; *Ethics, Nursing; *Imagination; Nurse's Role; Schools, Nursing/organization & administration; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UZ9LWYUE,journalArticle,2011,"Furiak, Nicolas M.; Ascher-Svanum, Haya; Klein, Robert W.; Smolen, Lee J.; Lawson, Anthony H.; Montgomery, William; Conley, Robert R.",Cost-effectiveness of olanzapine long-acting injection in the treatment of patients with schizophrenia in the United States: a micro-simulation economic decision model.,Current medical research and opinion,,1473-4877 0300-7995,10.1185/03007995.2011.554533,,"OBJECTIVE: To compare, from the perspective of third-party payers in the United States health care system, the cost-effectiveness of olanzapine long-acting injection (LAI, depot) with alternative antipsychotic agents including risperidone-LAI, paliperidone-LAI, haloperidol-LAI, and oral olanzapine, in the treatment of patients with schizophrenia who have been non-adherent or partially adherent with oral antipsychotics. RESEARCH DESIGN AND METHODS: A 1-year micro-simulation economic decision model was developed to simulate the dynamics of usual care of patients with schizophrenia who continue, discontinue, switch, or restart their medication. The model uses a range of clinical and cost parameters including adherence levels, relapse with and without hospitalization, quality-adjusted life years (QALYs), treatment discontinuation rates by reason, treatment-emergent adverse events, suicide, health care resource utilization, and direct health care costs. Published medical literature and a clinical expert panel were used to develop baseline model assumptions. OUTCOME MEASURES: Key model outputs include annual total direct cost (US$) per treatment and incremental cost-effectiveness values per additional QALY gained. RESULTS: Model results found that the olanzapine-LAI treatment strategy was more effective (greater QALYs) and less costly than risperidone-LAI, paliperidone-LAI, and haloperidol-LAI. In addition, olanzapine-LAI was both more effective and more costly, with an estimated incremental cost/QALY of $26,824 compared to oral olanzapine. The base-case and multiple sensitivity analyses found olanzapine-LAI to remain within acceptable cost-effective ranges (<$50,000) in terms of incremental cost/QALY gained. CONCLUSIONS: This micro-simulation model finds the olanzapine-LAI treatment strategy to result in better effectiveness and to be a cost-effective alternative compared to oral olanzapine and the LAI formulations of risperidone, paliperidone, and haloperidol in the treatment of non-adherent and partially adherent patients with schizophrenia in the United States. A key limitation is the assumption how LAI therapies compare to oral counterparts due to sparse head-to-head data. Further research is needed to verify baseline assumptions.",2011-04,26/11/2018 12:52,14/04/2020 08:34,,713-730,,4,27,,Curr Med Res Opin,,,,,,,,eng,,,,,,,PMID: 21265593,,,,"Humans; United States; Cost-Benefit Analysis; Medication Adherence; Computer Simulation; Algorithms; *Decision Support Techniques; Models, Economic; 00; Antipsychotic Agents/administration & dosage/adverse effects/economics; Benzodiazepines/*administration & dosage/adverse effects/*economics; Chemistry, Pharmaceutical; Injections/economics; Schizophrenia/*drug therapy/*economics; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, N9XXYUV4,journalArticle,2011,"Oliver, JoAnn S.; Ambrose, Sandra M.; Wynn, Stephanie D.",Using simulation innovation to facilitate learning nursing concepts: medical and mental health.,The Journal of nursing education,,0148-4834 0148-4834,10.3928/01484834-20110120-02,,,2011-02,26/11/2018 12:52,14/04/2020 08:35,,120,,2,50,,J Nurs Educ,,,,,,,,eng,,,,,,,PMID: 21261246,,,,"Humans; United States; Education, Nursing/*methods; *Manikins; 00; Mental Disorders/nursing; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 6NB9WDQP,journalArticle,2011,"Forsberg, Helena Hvitfeldt; Aronsson, Hakan; Keller, Christina; Lindblad, Staffan",Managing health care decisions and improvement through simulation modeling.,Quality management in health care,,1550-5154 1063-8628,10.1097/QMH.0b013e3182033bdc,,"Simulation modeling is a way to test changes in a computerized environment to give ideas for improvements before implementation. This article reviews research literature on simulation modeling as support for health care decision making. The aim is to investigate the experience and potential value of such decision support and quality of articles retrieved. A literature search was conducted, and the selection criteria yielded 59 articles derived from diverse applications and methods. Most met the stated research-quality criteria. This review identified how simulation can facilitate decision making and that it may induce learning. Furthermore, simulation offers immediate feedback about proposed changes, allows analysis of scenarios, and promotes communication on building a shared system view and understanding of how a complex system works. However, only 14 of the 59 articles reported on implementation experiences, including how decision making was supported. On the basis of these articles, we proposed steps essential for the success of simulation projects, not just in the computer, but also in clinical reality. We also presented a novel concept combining simulation modeling with the established plan-do-study-act cycle for improvement. Future scientific inquiries concerning implementation, impact, and the value for health care management are needed to realize the full potential of simulation modeling.",2011-03,26/11/2018 12:52,14/04/2020 08:34,,15-29,,1,20,,Qual Manag Health Care,,,,,,,,eng,,,,,,,PMID: 21192204,,,,"Humans; *Computer Simulation; Communication; Research Design; Quality Improvement; *Decision Making; Decision Support Systems, Clinical/*organization & administration; 1; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MX748WA9,journalArticle,2011,"Csoka, Maria; Deutsch, Tibor","[Innovative education: simulation-based training at the Institute of Health Sciences, Semmelweis University, Hungary].",Orvosi hetilap,,0030-6002 0030-6002,10.1556/OH.2011.29016,,"In Hungary, the Institute of Health Sciences at Semmelweis University was the first institution to introduce patient simulation-based practical training of non-physician professionals. Before introducing this novel educational methodology, students could only practice particular examinations and interventions on demonstration tools. Using the simulator they can also follow and analyze the effects of the interventions that have been made. The high fidelity, adult Human Patients Emergency Care Simulator (HPS-ECS, Medical Education Technologies Incorporation, Sarasota, Florida, USA) is particularly suitable for acquiring skills related to the management of various emergency situations. The 180 cm and 34 kg mannequin which can operate in lying and sitting positions has both respiration and circulation which can be examined the same way as in a living person. It is capable to produce several physical and clinical signs such as respiration with chest movement, electric cardiac activity, palpable pulse, and measurable blood pressure. In addition, it can also exhibit blinking, swelling of the tongue and whole-body trembling while intestinal, cardiac and pulmonary sounds can equally be examined. The high fidelity simulator allows various interventions including monitoring, oxygen therapy, bladder catheterization, gastric tube insertion, injection, infusion and transfusion therapy to be practiced as part of complex patient management. Diagnostic instruments such as ECG recorder, sphygmomanometer, pulse-oxymeter can be attached to the simulator which can also respond to different medical interventions such as intubation, defibrillation, pacing, liquid supplementing, and blood transfusion. The mannequin's physiological response can be followed up and monitored over time to assess whether the selected intervention has been proven adequate to achieve the desired outcome. Authors provide a short overview of the possible applications of clinical simulation for education and training in health sciences, and present how patient simulator has been embedded in various practical courses as part of different curriculum designed for different health care specialties.",02/01/2011,26/11/2018 12:52,14/04/2020 08:34,,27-33,,1,152,,Orv Hetil,,,,,,,,hun,,,,,,,PMID: 21177228,,,,"Humans; Adult; Curriculum; *Manikins; Clinical Competence/standards; 00; Education, Public Health Professional/*methods; Hungary; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, R4EF7V3W,journalArticle,2010,"Taboy, Celine H.; Chapman, Will; Albetkova, Adilya; Kennedy, Sarah; Rayfield, Mark A.",Integrated Disease Investigations and Surveillance planning: a systems approach to strengthening national surveillance and detection of events of public health importance in support of the International Health Regulations.,BMC public health,,1471-2458 1471-2458,10.1186/1471-2458-10-S1-S6,,"The international community continues to define common strategic themes of actions to improve global partnership and international collaborations in order to protect our populations. The International Health Regulations (IHR[2005]) offer one of these strategic themes whereby World Health Organization (WHO) Member States and global partners engaged in biosecurity, biosurveillance and public health can define commonalities and leverage their respective missions and resources to optimize interventions. The U.S. Defense Threat Reduction Agency's Cooperative Biological Engagement Program (CBEP) works with partner countries across clinical, veterinary, epidemiological, and laboratory communities to enhance national disease surveillance, detection, diagnostic, and reporting capabilities. CBEP, like many other capacity building programs, has wrestled with ways to improve partner country buy-in and ownership and to develop sustainable solutions that impact integrated disease surveillance outcomes. Designing successful implementation strategies represents a complex and challenging exercise and requires robust and transparent collaboration at the country level. To address this challenge, the Laboratory Systems Development Branch of the U.S. Centers for Disease Control and Prevention (CDC) and CBEP have partnered to create a set of tools that brings together key leadership of the surveillance system into a deliberate system design process. This process takes into account strengths and limitations of the existing system, how the components inter-connect and relate to one another, and how they can be systematically refined within the local context. The planning tools encourage cross-disciplinary thinking, critical evaluation and analysis of existing capabilities, and discussions across organizational and departmental lines toward a shared course of action and purpose. The underlying concepts and methodology of these tools are presented here.",03/12/2010,26/11/2018 12:52,14/04/2020 08:35,,S6,,,10 Suppl 1,,BMC Public Health,,,,,,,,eng,,,,,,,PMID: 21143828 PMCID: PMC3005578,,,,"Humans; United States; World Health Organization; Centers for Disease Control and Prevention (U.S.); Leadership; Public Health/*legislation & jurisprudence; Capacity Building; *Systems Integration; Public Policy; *International Cooperation; 1; *Population Surveillance; Social Control, Formal; system approach; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BIDVT8YP,journalArticle,2010,"Lower, Tony E.; Fragar, Lyn; Depcynzksi, Julie; Fuller, Jeffrey; Challinor, Kathy; Williams, Warwick",Social network analysis for farmers' hearing services in a rural community.,Australian journal of primary health,,1448-7527 1448-7527,,,"This study aimed to define current hearing health service networks for farming families in a major regional centre in New South Wales, in order to identify approaches that can strengthen local service provision. A pilot survey of individuals and agencies that potentially work with farmers was undertaken and a social network analysis completed to assess the self-reported links of agencies with each other. Thirteen agencies with a role in hearing health service provision participated with results indicating that nurse audiometrists, WorkCover NSW and agricultural retailers have the lead role in disseminating relevant information within the network. For client referrals the nurse audiometrist, private audiometry services, general practitioners, ear, nose and throat specialists and industry groups played the major roles. Social network analysis can assist in defining hearing health networks and can be used to highlight potential actions that can strengthen networks to enhance services for farmers and their families.",2010,26/11/2018 12:52,14/04/2020 08:34,,47-51,,1,16,,Aust J Prim Health,,,,,,,,eng,,,,,,,PMID: 21133298,,,,"Humans; Pilot Projects; Interinstitutional Relations; Community Networks/*organization & administration; New South Wales; 00; Rural Health Services/*organization & administration; Agricultural Workers' Diseases/diagnosis/etiology/*therapy; Hearing Loss, Noise-Induced/diagnosis/etiology/*therapy; Occupational Exposure/adverse effects/statistics & numerical data; Referral and Consultation/statistics & numerical data; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5GZ8TKFX,journalArticle,2010,"Pedigo, Ashley S.; Odoi, Agricola",Investigation of disparities in geographic accessibility to emergency stroke and myocardial infarction care in East tennessee using geographic information systems and network analysis.,Annals of epidemiology,,1873-2585 1047-2797,10.1016/j.annepidem.2010.06.013,,"PURPOSE: Stroke and myocardial infarction (MI) require timely geographic accessibility to emergency care. Historically, studies used straight line distances as measures of geographic accessibility. Recently, travel time has been recognized as a better indicator of accessibility because travel impedances can be considered. This study used finer grained transportation data and network analysis to investigate neighborhood disparities in travel time to emergency stroke and MI care. METHODS: Travel times to stroke and cardiac centers were computed using network analysis, while considering distance, speed limit, road connectivity, and turn impedances. Neighborhoods within 30, 60, or 90 minutes travel were identified. Travel time by air ambulance was calculated and adjusted for flying speed and some delays. RESULTS: Approximately 8% and 15% of the study population did not have timely geographic accessibility to emergency stroke and MI care, respectively. Populations with poor access were located in rural areas. The entire study population had timely access by air ambulance. CONCLUSIONS: This study identified disparities in geographic accessibility to emergency stroke and MI care in East Tennessee. Use of air ambulance or telemedicine could play a vital role in addressing these disparities. This information is important for evidence-based health planning and resource allocation.",2010-12,26/11/2018 12:52,14/04/2020 08:35,,924-930,,12,20,,Ann Epidemiol,,,,,,,,eng,Copyright (c) 2010 Elsevier Inc. All rights reserved.,,,,,,PMID: 21074107,,,,Humans; Healthcare Disparities; Algorithms; Time Factors; Health Services Accessibility/*statistics & numerical data; Tennessee; Residence Characteristics; 00; Catchment Area (Health); Geography; Geographic Information Systems; *Rural Health Services; *Hospitals/statistics & numerical data; *Myocardial Infarction/therapy; *Stroke/therapy; Censuses; Transportation of Patients/methods/*statistics & numerical data; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 93JEIWE9,journalArticle,2010,"Kelly, Michelle; Flanagan, Brendan",Trends and developments in the use of health care simulation.,"Collegian (Royal College of Nursing, Australia)",,1322-7696 1322-7696,,,,2010,26/11/2018 12:52,14/04/2020 08:34,,101-102,,3,17,,Collegian,,,,,,,,eng,,,,,,,PMID: 21046961,,,,Humans; *Patient Simulation; Australia; Health Personnel/*education; *Manikins; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TLGMZQZX,journalArticle,2010,"Norman, Cameron D.; Charnaw-Burger, Jill; Yip, Andrea L.; Saad, Sam; Lombardo, Charlotte",Designing health innovation networks using complexity science and systems thinking: the CoNEKTR model.,Journal of evaluation in clinical practice,,1365-2753 1356-1294,10.1111/j.1365-2753.2010.01534.x,,"RATIONALE, AIMS AND OBJECTIVES: Complex problems require strategies to engage diverse perspectives in a focused, flexible manner, yet few options exist that fit with the current health care and public health system constraints. The Complex Network Electronic Knowledge Translation Research model (CoNEKTR) brings together complexity science, design thinking, social learning theories, systems thinking and eHealth technologies together to support a sustained engagement strategy for social innovation support and enhancing knowledge integration. METHODS: The CoNEKTR model adapts elements of other face-to-face social organizing methods and combines it with social media and electronic networking tools to create a strategy for idea generation, refinement and social action. Drawing on complexity science, a series of networking and dialogue-enhancing activities are employed to bring diverse groups together, facilitate dialogue and create networks of networks. RESULTS: Ten steps and five core processes informed by complexity science have been developed through this model. Concepts such as emergence, attractors and feedback play an important role in facilitating networking among participants in the model. CONCLUSIONS: Using a constrained, focused approach informed by complexity science and using information technology, the CoNEKTR model holds promise as a means to enhance system capacity for knowledge generation, learning and action while working within the limitations faced by busy health professionals.",2010-10,26/11/2018 12:52,14/04/2020 08:35,,1016-1023,,5,16,,J Eval Clin Pract,,,,,,,,eng,(c) 2010 Blackwell Publishing Ltd.,,,,,,PMID: 20846290,,,,"Humans; Health Promotion; *Public Health; *Systems Analysis; *Models, Theoretical; *Social Support; Health Knowledge, Attitudes, Practice; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, B5DDDY2F,journalArticle,2010,"Caro, Jaime J.; Moller, Jorgen; Getsios, Denis",Discrete event simulation: the preferred technique for health economic evaluations?,Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research,,1524-4733 1098-3015,10.1111/j.1524-4733.2010.00775.x,,"OBJECTIVES: To argue that discrete event simulation should be preferred to cohort Markov models for economic evaluations in health care. METHODS: The basis for the modeling techniques is reviewed. For many health-care decisions, existing data are insufficient to fully inform them, necessitating the use of modeling to estimate the consequences that are relevant to decision-makers. These models must reflect what is known about the problem at a level of detail sufficient to inform the questions. Oversimplification will result in estimates that are not only inaccurate, but potentially misleading. RESULTS: Markov cohort models, though currently popular, have so many limitations and inherent assumptions that they are inadequate to inform most health-care decisions. An event-based individual simulation offers an alternative much better suited to the problem. A properly designed discrete event simulation provides more accurate, relevant estimates without being computationally prohibitive. It does require more data and may be a challenge to convey transparently, but these are necessary trade-offs to provide meaningful and valid results. CONCLUSION: In our opinion, discrete event simulation should be the preferred technique for health economic evaluations today.",2010-12,26/11/2018 12:52,14/04/2020 08:34,,1056-1060,,8,13,,Value Health,,,,,,,,eng,"(c) 2010, International Society for Pharmacoeconomics and Outcomes Research (ISPOR).",,,,,,PMID: 20825626,,,,"Humans; Markov Chains; *Models, Statistical; *Health Care Costs; *Decision Support Techniques; Models, Economic; Health Policy/economics; 1; Cost-Benefit Analysis/methods; ******To read; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Y2EN7IB3,journalArticle,2010,"Davis, Peter; Lay-Yee, Roy; Pearson, Janet",Using micro-simulation to create a synthesised data set and test policy options: the case of health service effects under demographic ageing.,"Health policy (Amsterdam, Netherlands)",,1872-6054 0168-8510,10.1016/j.healthpol.2010.05.014,,"OBJECTIVES: To assess micro-simulation for testing policy options under demographic ageing. METHODS: Individual-level data were drawn from the New Zealand Health Survey (1996/7 and 2002/3), a national survey of ambulatory care in New Zealand (2001/2), and the Australian National Health Survey (1995). Health service effects assessed were visits to the family doctor, and rates of prescribing and referral. We created a representative set of synthetic health histories by imputation and tested the health service effects of different policy scenarios. These were created by varying ageing and morbidity trajectories, degree of social support available, and intensity of practitioner behaviour. RESULTS: The set of synthetic health histories created by combining the data sources generated outcomes reasonably close to external benchmarks. Altering the age distribution of 2002 to approximate settings for 2021 produced no change in rates of visiting, prescribing, or referral for the 65-and-over population. Quantifying the health service effects of different scenarios showed no impact on visit rates by varying social support, but substantial differences for visits between high and low morbidity scenarios and for prescribing and referral rates according to practitioner behaviour. CONCLUSIONS: There is potential for micro-simulation to assist in the synthesis of data and to help quantify scenario options for policy development.",2010-10,26/11/2018 12:52,14/04/2020 08:34,,267-274,,02-Mar,97,,Health Policy,,,,,,,,eng,Copyright (c) 2010 Elsevier Ireland Ltd. All rights reserved.,,,,,,PMID: 20800762,,,,"*Health Policy; Humans; Adult; Female; Male; Middle Aged; Reproducibility of Results; *Health Planning; Aged; Child; Adolescent; Computer Simulation; Child, Preschool; Infant; *Decision Support Techniques; Infant, Newborn; Australia/epidemiology; Morbidity; 1; *Population Dynamics; New Zealand/epidemiology; Primary Health Care/*organization & administration/utilization; 210",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8ILKQ7BN,journalArticle,2010,"Abduvaliev, A. A.; Gil'dieva, M. S.; Khidirov, B. N.; Saidalieva, M.; Saatov, T. S.",[Computer simulation of thyroid regulatory mechanisms in health and malignancy].,Klinicheskaia laboratornaia diagnostika,,0869-2084 0869-2084,,,"The paper describes a computer model for regulation of the number of thyroid follicular cells in health and malignancy. The authors'computer program for mathematical simulation of the regulatory mechanisms of a thyroid follicular cellular community cannot be now referred to as good commercial products. For commercialization of this product, it is necessary to draw up a direct relation of the introduced corrected values from the actually existing normal values, such as the peripheral blood concentrations of thyroid hormones or the mean values of endocrine tissue mitotic activity. However, the described computer program has been also used in researches by our scientific group in the study of thyroid cancer. The available biological experimental data and theoretical provisions on thyroid structural and functional organization at the cellular level allow one to construct mathematical models for quantitative analysis of the regulation of the size of a cellular community of a thyroid follicle in health and abnormalities, by using the method for simulation of the regulatory mechanisms of living systems and the equations of cellular community regulatory communities.",2010-07,26/11/2018 12:52,14/04/2020 08:34,,23-27,,7,,,Klin Lab Diagn,,,,,,,,rus,,,,,,,PMID: 20795403,,,,"Humans; *Software; *Models, Biological; *Computer Simulation; 00; Cell Count; Thyroid Gland/*cytology/physiology; Thyroid Neoplasms/*pathology/physiopathology; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FVSIT3AD,journalArticle,2010,"Kitzman-Ulrich, Heather; Wilson, Dawn K.; St George, Sara M.; Lawman, Hannah; Segal, Michelle; Fairchild, Amanda","The integration of a family systems approach for understanding youth obesity, physical activity, and dietary programs.",Clinical child and family psychology review,,1573-2827 1096-4037,10.1007/s10567-010-0073-0,,"Rates of overweight in youth have reached epidemic proportions and are associated with adverse health outcomes. Family-based programs have been widely used to treat overweight in youth. However, few programs incorporate a theoretical framework for studying a family systems approach in relation to youth health behavior change. Therefore, this review provides a family systems theory framework for evaluating family-level variables in weight loss, physical activity, and dietary approaches in youth. Studies were reviewed and effect sizes were calculated for interventions that manipulated the family system, including components that targeted parenting styles, parenting skills, or family functioning, or which had novel approaches for including the family. Twenty-one weight loss interventions were identified, and 25 interventions related to physical activity and/or diet were identified. Overall, family-based treatment programs that incorporated training for authoritative parenting styles, parenting skills, or child management, and family functioning had positive effects on youth weight loss. Programs to improve physical activity and dietary behaviors that targeted the family system also demonstrated improvements in youth health behaviors; however, direct effects of parent-targeted programming is not clear. Both treatment and prevention programs would benefit from evaluating family functioning and parenting styles as possible mediators of intervention outcomes. Recommendations are provided to guide the development of future family-based obesity prevention and treatment programs for youth.",2010-09,26/11/2018 12:52,14/04/2020 08:34,,231-253,,3,13,,Clin Child Fam Psychol Rev,,,,,,,,eng,,,,,,,PMID: 20689989 PMCID: PMC3293190,,,,"Humans; Randomized Controlled Trials as Topic; Female; Male; Risk Factors; Child; Adolescent; *Systems Theory; *Motor Activity; Combined Modality Therapy; 00; Cognitive Therapy/methods; Diet, Reducing/*psychology; Education/methods; Family Conflict/psychology; Family Therapy/*methods; Obesity/prevention & control/*psychology/therapy; Parenting/psychology; Weight Loss; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EGMUJ7CW,journalArticle,2010,"Nuijten, Mark; Andress, Dennis L.; Marx, Steven E.; Curry, Alistair S.; Sterz, Raimund",Cost Effectiveness of Paricalcitol versus a non-selective vitamin D receptor activator for secondary hyperparathyroidism in the UK: a chronic kidney disease markov model.,Clinical drug investigation,,1173-2563 1173-2563,10.2165/11536310-000000000-00000,,"BACKGROUND: secondary hyperparathyroidism (SHPT) is a common complication of chronic kidney disease (CKD) and a frequent cause of clinically significant bone disease. Non-selective vitamin D receptor (VDR) activator treatment has been used to treat the condition but is ineffective for many patients with hypercalcaemia and hyperphosphataemia and may precipitate worsening of their condition. Compared with non-selective VDR activator treatment, use of the VDR ligand paricalcitol may increase survival and reduce the risk of morbidities in patients with SHPT, which may have health economic consequences. OBJECTIVE: the objective of this study was to determine the cost effectiveness of paricalcitol versus a non-selective VDR activator for the treatment of SHPT in patients with CKD in the UK setting. METHODS: A Markov process model was developed employing data sources from the published literature, paricalcitol clinical trials and observational studies, official UK price/tariff lists and national population statistics. The comparator was alfacalcidol, a non-selective VDR activator medication. The primary perspective of the study was that of the UK National Health Service (NHS). The efficacy outcomes (reductions in SHPT, proteinuria, complications and mortality) were extrapolated to: number of life-years gained (LYG) and number of quality-adjusted life-years (QALYs). Clinical and economic outcomes were discounted at 3.5%. The year of costing for costs determined in the study was 2006. RESULTS: the reference case analysis was a 10-year time horizon, based on a comparison of paricalcitol with a non-selective VDR activator, which is started in CKD stage 3 (moderate reduction in glomerular filtration rate [GFR] with kidney damage) and continued in CKD stage 4 (severe reduction in GFR) and CKD stage 5 (established kidney failure). The use of paricalcitol leads to an additional medical cost of pound3224 ($US5970). The health benefits of paricalcitol lead to an increase in LYG of 0.52 and a gain in QALYs of 0.465. Therefore the use of paricalcitol results in an incremental cost-effectiveness ratio of pound6933/QALY ($US12 840/QALY) from the primary perspective of the NHS. One-way sensitivity analyses and probabilistic sensitivity analyses confirmed the robustness of the model. CONCLUSION: this model showed that the favourable clinical benefit of paricalcitol results in positive short- and long-term health economic benefits. This study suggests that the use of paricalcitol in patients with early CKD may be cost effective from the UK NHS perspective versus non-selective VDR activator medication.",2010,26/11/2018 12:52,14/04/2020 08:35,,545-557,,8,30,,Clin Drug Investig,,,,,,,,eng,,,,,,,PMID: 20586517,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; *Markov Chains; Chronic Disease; 00; Ergocalciferols/economics/*therapeutic use; Hydroxycholecalciferols/*therapeutic use; Hyperparathyroidism, Secondary/drug therapy; Kidney Diseases/*complications; Receptors, Calcitriol/*drug effects; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IWHVJ2UM,journalArticle,2010,"Wu, Bin; Li, Te; Chen, Huafeng; Shen, Jinfang",Cost-effectiveness of nucleoside analog therapy for hepatitis B in China: a Markov analysis.,Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research,,1524-4733 1098-3015,10.1111/j.1524-4733.2010.00733.x,,"OBJECTIVES: The aim of this study was to investigate the economic consequences of nucleoside analog therapy for hepatitis B treatment in China. METHODS: A cost-utility analysis of treatments for HBeAg-positive and HBeAg-negative chronic hepatitis B (CHB) was conducted using a Markov model, in which patients' yearly transitions between different health states were tracked. Patients were tracked as they moved between the following health states: CHB, HBeAg seroconversion (HBeAg-positive CHB patients can have this special health state), virologic resistance, virologic response, compensated cirrhosis, decompensated cirrhosis, hepatocellular carcinoma, liver transplantation, and death. The transition parameters were derived either from systematic reviews of the literature or from previous economic studies. Cost and utility data came from studies based on a Chinese CHB cohort. One-way sensitivity analyses as well as second-order Monte Carlo and probabilistic sensitivity analyses were performed. RESULTS: The entecavir strategy yielded the most quality-adjusted life years (QALYs) for both HBeAg-positive and HBeAg-negative patients when compared with the ""no treatment,"" the lamivudine, the adefovir, and the telbivudine strategies. The risks of complications and mortality also decreased. In the economic analysis, the ""no treatment"" strategy was the least effective, whereas the entecavir strategy was both the least expensive and the most cost-effective option, followed by telbivudine and lamivudine. The probabilistic sensitivity analysis showed that the entecavir strategy would result in improved cost-effectiveness in >90% of cases at a threshold of $20,000 per QALY. In a one-way sensitivity analysis, the most influential parameters impacting the model's robustness were the utilities of the CHB and virologic response health states. CONCLUSIONS: In China, when treating both HBeAg-positive and HBeAg-negative CHB populations, entecavir is the most cost-effective option when compared with lamivudine, adefovir, and telbivudine.",2010-08,26/11/2018 12:52,14/04/2020 08:35,,592-600,,5,13,,Value Health,,,,,,,,eng,,,,,,,PMID: 20561341,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Markov Chains; Monte Carlo Method; Models, Statistical; China; Models, Economic; Serologic Tests; 00; Adenine/analogs & derivatives/economics/therapeutic use; Antiviral Agents/*economics/therapeutic use; Guanine/*analogs & derivatives/economics/therapeutic use; Hepatitis B e Antigens/blood/immunology; Hepatitis B, Chronic/*drug therapy/economics/immunology; Lamivudine/economics/therapeutic use; Nucleosides/economics/therapeutic use; Organophosphonates/economics/therapeutic use; Pyrimidinones/economics/therapeutic use; Reverse Transcriptase Inhibitors/economics/therapeutic use; Thymidine/analogs & derivatives; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GLENDFSI,journalArticle,2011,"Hazen, Gordon; Li, Zhe",Cohort decomposition for Markov cost-effectiveness models.,Medical decision making : an international journal of the Society for Medical Decision Making,,1552-681X 0272-989X,10.1177/0272989X10368999,,"Cohort analysis is a widespread tool for computing expected costs and quality-adjusted life years (QALYs) in Markov models for medical cost-effectiveness analyses. Although not always explicitly identified, such models commonly have multiple simple factors, or components. In these, a health state consists of a multiple component vector, one component for each factor, and arbitrary combinations of components are possible. The authors show here that when the model does not assume any probabilistic dependence among these factors, then a standard cohort analysis may be decomposed into several independent cohort analyses, one for each factor, and the results may be combined to produce desired expected costs and QALYs. These single-factor cohort analyses are not only simpler but also computationally more efficient. The authors derive the appropriate formulas for this cohort decomposition in discrete time and give several examples of their use based on published cost-effectiveness analyses. Explicitly identifying the simple factors of which a model is composed allows these factors to be portrayed graphically. Graphical depiction of the simple factors that comprise a model reduces model complexity, makes model formulation easier and more transparent, and thereby facilitates peer inspection and critique.",2011-02,26/11/2018 12:52,14/04/2020 08:34,,19-34,,1,31,,Med Decis Making,,,,,,,,eng,,,,,,,PMID: 20530723,,,,"Humans; United States; Health Care Costs; *Models, Economic; *Quality-Adjusted Life Years; Risk Assessment; *Markov Chains; Time; Models, Statistical; Risk; 00; Population Surveillance; *Cohort Studies; Cost-Benefit Analysis/*methods/statistics & numerical data; Factor Analysis, Statistical; Neoplasms; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JMJNXZDQ,journalArticle,2010,"Libin, Alexander; Lauderdale, Manon; Millo, Yuri; Shamloo, Christine; Spencer, Rachel; Green, Brad; Donnellan, Joyce; Wellesley, Christine; Groah, Suzanne",Role-playing simulation as an educational tool for health care personnel: developing an embedded assessment framework.,"Cyberpsychology, behavior and social networking",,2152-2723 2152-2715,,,"Simulation- and video game-based role-playing techniques have been proven effective in changing behavior and enhancing positive decision making in a variety of professional settings, including education, the military, and health care. Although the need for developing assessment frameworks for learning outcomes has been clearly defined, there is a significant gap between the variety of existing multimedia-based instruction and technology-mediated learning systems and the number of reliable assessment algorithms. This study, based on a mixed methodology research design, aims to develop an embedded assessment algorithm, a Knowledge Assessment Module (NOTE), to capture both user interaction with the educational tool and knowledge gained from the training. The study is regarded as the first step in developing an assessment framework for a multimedia educational tool for health care professionals, Anatomy of Care (AOC), that utilizes Virtual Experience Immersive Learning Simulation (VEILS) technology. Ninety health care personnel of various backgrounds took part in online AOC training, choosing from five possible scenarios presenting difficult situations of everyday care. The results suggest that although the simulation-based training tool demonstrated partial effectiveness in improving learners' decision-making capacity, a differential learner-oriented approach might be more effective and capable of synchronizing educational efforts with identifiable relevant individual factors such as sociobehavioral profile and professional background.",2010-04,26/11/2018 12:52,14/04/2020 08:34,,217-224,,2,13,,Cyberpsychol Behav Soc Netw,,,,,,,,eng,,,,,,,PMID: 20528282,,,,"Humans; Adult; Female; Male; Middle Aged; Aged; Computer Simulation; Health Personnel/*education; 00; Education, Continuing/*methods; *Role Playing; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, LBUGPNXC,journalArticle,2010,"Pagliccia, Nino; Spiegel, Jerry; Alegret, Milagros; Bonet, Mariano; Martinez, Barbara; Yassi, Annalee",Network analysis as a tool to assess the intersectoral management of health determinants at the local level: a report from an exploratory study of two Cuban municipalities.,Social science & medicine (1982),,1873-5347 0277-9536,10.1016/j.socscimed.2010.03.041,,"Intersectoral action on health determinants has long been recognized as an important factor in achieving better population health. Nevertheless, there is no process that provides empirical evidence to policy-makers on the extent of intersectoral collaboration. We aimed to fill this gap by conducting case studies in two municipalities in Cuba, a country well known for its intersectoral practice and good health outcomes. We surveyed an intentional sample of key members of Health Councils - virtual intersectoral spaces in Cuba - about links and related actions they had with other sectors on eleven health determinants. Using network analysis we were able to produce measures to evaluate and characterize the network of sectors. Findings show that the two municipalities were similar in reported importance of health determinants, extent of long-term engagement in intra-sectors actions and level of collaboration with other sectors for virtually all determinants. Municipalities also showed similar overall levels of collaboration for most determinants when considered as a network of different sectors (network density). However municipalities showed differences in the central role played by some sectors (centrality index). We further used the network analysis blockmodeling technique to typify the municipal Health Councils. We found that while one Health Council can be typified by a single well connected network structure, the other has two distinct structures with more sparse connections. We conclude that intersectoral collaboration can be assessed by the use of network analysis measurements. This approach is novel and provides evidence to decision-makers about their role and their effort towards collaboration in achieving better health outcomes.",2010-07,26/11/2018 12:52,14/04/2020 08:35,,394-399,,2,71,,Soc Sci Med,,,,,,,,eng,Copyright 2010 Elsevier Ltd. All rights reserved.,,,,,,PMID: 20488603,,,,Humans; Health Status Indicators; Surveys and Questionnaires; *Cooperative Behavior; Community Networks/*organization & administration; 1; *Needs Assessment; Cities; Cuba; Health Care Sector; Health Planning Councils; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GMNPP4ZK,journalArticle,2010,"Proano, Lawrence; Foggle, John; Partridge, Robert",The use of medical simulation to train health care providers to practice in international settings.,"Medicine and health, Rhode Island",,1086-5462 1086-5462,,,,2010-03,26/11/2018 12:52,14/04/2020 08:35,,86-87,,3,93,,Med Health R I,,,,,,,,eng,,,,,,,PMID: 20415114,,,,"Humans; Emergency Medicine/*education; *Computer Simulation; *Clinical Competence; Global Health; *Manikins; Cultural Competency; *International Cooperation; 00; *Education, Medical; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MNRXH69S,journalArticle,2010,"Mar, Javier; Antonanzas, Fernando; Pradas, Roberto; Arrospide, Arantzazu",[Probabilistic Markov models in economic evaluation of health technologies: a practical guide].,Gaceta sanitaria,,1578-1283 0213-9111,10.1016/j.gaceta.2010.02.006,,"OBJECTIVE: Markov models are the standard method used in cost-effectiveness studies to represent the natural history of disease. The objective of this study was to show the key elements in building probabilistic Markov models. METHODS: We used the example of a new treatment for a generic disease. A probabilistic Markov model was constructed using statistical distributions. Monte Carlo simulations were carried out to obtain the probabilistic sensitivity analysis. The results were analyzed in terms of the cost-effectiveness plane and acceptability curve. RESULTS: The incremental cost-effectiveness rate for the average patient was 22,855 euro/quality adjusted life years (QALY). In the probabilistic sensitivity analysis, the results from all simulations were located in the northeast quadrant, corresponding to positive cost and effectiveness. However, 67% of the simulations were below the threshold of 30,000 euro/QALY. CONCLUSION: The use of probabilistic Markov models requires the integration of concepts from economics, epidemiology, statistics, and the clinical setting. Some stages of the process, such as the construction and processing of these models, the management of absolute and relative risks and of statistical distributions, often pose major difficulties but are key steps required to reproduce the disease with validity.",2010-06,26/11/2018 12:52,14/04/2020 08:34,,209-214,,3,24,,Gac Sanit,,,,,,,,spa,Copyright 2009 SESPAS. Published by Elsevier Espana. All rights reserved.,,,,,,PMID: 20409616,,,,"Humans; Cost-Benefit Analysis; *Models, Statistical; *Markov Chains; 00; Biomedical Technology/*economics; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HIFIZH66,journalArticle,2010,"Getsios, Denis; Blume, Steve; Ishak, K. Jack; Maclaine, Grant D. H.",Cost effectiveness of donepezil in the treatment of mild to moderate Alzheimer's disease: a UK evaluation using discrete-event simulation.,PharmacoEconomics,,1179-2027 1170-7690,10.2165/11531870-000000000-00000,,"Recommendations in the UK suggest restricting treatment of Alzheimer's disease with cholinesterase inhibitors, on cost-effectiveness grounds, to patients with moderate cognitive decline. As the economic analyses that informed these recommendations have been the subject of debate, we sought to address the potential limitations of existing models and produce estimates of donepezil treatment cost effectiveness in the UK using the most recent available data and simulation techniques. A discrete-event simulation was developed that predicts progression of Alzheimer's disease through correlated changes in cognition, behavioural disturbance and function. Patient-level data from seven randomized, placebo-controlled donepezil trials and a 7-year follow-up registry provided the basis for modeling longitudinal outcomes. Individuals in the simulation were assigned unique demographic and clinical characteristics and then followed for 10 years, with severity of disease tracked on continuous scales. Patient mix and costs were developed from UK-specific literature. Analyses were run for severity subgroups to evaluate outcomes for sub-populations with disease of mild versus moderate severity from both a healthcare payer and societal perspective. All costs are reported in pound, year 2007 values, and all outcomes are discounted at 3.5% per annum. Over 10 years, treatment of all patients with mild to moderate disease reduces overall direct medical costs by an average of over pound2300 per patient. When unpaid caregiver time is also taken into consideration, savings increase to over pound4700 per patient. Compared with untreated patients, patients receiving donepezil experience a discounted gain in QALYs averaging 0.11, with their caregivers gaining, on average, 0.01 QALYs. For the subset of patients starting treatment with more severe disease, savings are more modest, averaging about pound1600 and pound3750 from healthcare and societal perspectives, respectively. In probabilistic sensitivity analyses, donepezil dominated no treatment between 57% and 62% of replications when only medical costs were considered, and between 74% and 79% of replications when indirect costs were included, with results more favourable for treatment initiation in the mild versus moderate severity stages of the disease. Although the simulation results are not definitive, they suggest that donepezil leads to health benefits and cost savings when used to treat mild to moderately severe Alzheimer's disease in the UK. They also indicate that both benefits and savings may be greatest when treatment is started while patients are still in the mild stages of Alzheimer's disease.",2010,26/11/2018 12:52,14/04/2020 08:34,,411-427,,5,28,,Pharmacoeconomics,,,,,,,,eng,,,,,,,PMID: 20402542,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Treatment Outcome; Female; Male; *Models, Economic; Aged; Health Care Costs/statistics & numerical data; *Computer Simulation; Aged, 80 and over; Algorithms; Cost of Illness; United Kingdom; Registries; Databases, Factual; Alzheimer Disease/diagnosis/*drug therapy/*economics/mortality; Caregivers/economics; Drug Costs/statistics & numerical data; Indans/*economics/*therapeutic use; Nootropic Agents/economics/therapeutic use; Piperidines/*economics/*therapeutic use; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Q3NIB9W2,journalArticle,2010,"Kameg, Kirstyn; Howard, Valerie M.; Clochesy, John; Mitchell, Ann M.; Suresky, Jane M.",The impact of high fidelity human simulation on self-efficacy of communication skills.,Issues in mental health nursing,,1096-4673 0161-2840,10.3109/01612840903420331,,"Communication is a critical component of nursing education as well as a necessity in maintaining patient safety. Psychiatric nursing is a specialty that emphasizes utilization of communication skills to develop therapeutic relationships. Nursing students are frequently concerned and anxious about entering the mental health setting for their first clinical placement. High fidelity human simulation (HFHS) is one method that can be used to allow students to practice and become proficient with communication skills. The purpose of this study was to compare the effectiveness of two educational delivery methods, traditional lecture and HFHS, on senior level nursing student's self-efficacy with respect to communicating with patients experiencing mental illness. The results of this study support the use of HFHS to assist in enhancing undergraduate students' self-efficacy in communicating with patients who are experiencing mental illness.",2010-05,26/11/2018 12:52,14/04/2020 08:34,,315-323,,5,31,,Issues Ment Health Nurs,,,,,,,,eng,,,,,,,PMID: 20394477,,,,"Humans; Program Evaluation; Surveys and Questionnaires; Clinical Competence; Female; Male; Nursing Education Research; Students, Nursing/*psychology; *Self Efficacy; Psychiatric Nursing/*education; Educational Measurement; *Communication; Education, Nursing, Baccalaureate/*methods; Attitude of Health Personnel; Patient Simulation; Nurse-Patient Relations; Pennsylvania; *Manikins; Videotape Recording; 00; Computer-Assisted Instruction/methods; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, N847WXCW,journalArticle,2010,"Kegler, Michelle C.; Rigler, Jessica; Ravani, Maya K.",Using network analysis to assess the evolution of organizational collaboration in response to a major environmental health threat.,Health education research,,1465-3648 0268-1153,10.1093/her/cyq022,,"Effective inter-organizational collaboration is essential to a community's ability to leverage social and material resources for community problem solving, particularly in the face of complex public health problems. This study used network analysis to document the evolution of collaboration among 21 organizations in the Tar Creek Superfund site in northeastern Oklahoma from 1997 to 2005. The Tar Creek Superfund site was part of a major lead and zinc mining operation and suffers from widespread heavy metal contamination. An organizational network of 21 organizations and a subset of eight tribes were assessed through interviews at three points in time for density and centrality. In addition to collaboration on any topic, we examined information exchange and joint planning related to lead. Density scores were consistently higher in 2005 than in 1997 for both the full and tribal networks. Centralization indices for information exchange showed a marked reduction in the hierarchical structure of information exchange over time. Of particular note is that tribal linkages with local, state and federal agencies increased over time, as did inter-tribal linkages to address the lead issue.",2010-06,26/11/2018 12:52,14/04/2020 08:34,,413-424,,3,25,,Health Educ Res,,,,,,,,eng,,,,,,,PMID: 20385624 PMCID: PMC2872616,,,,"Humans; Interviews as Topic; Interinstitutional Relations; 1; Community Networks/*organization & administration/statistics & numerical data; Environmental Health/*organization & administration; Hazardous Waste/adverse effects/*prevention & control; Indians, North American; Metals, Heavy/adverse effects; Mining/standards; Oklahoma; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YLSP2VH3,journalArticle,2010,"Chen, Bai-lian; Li, En-dong; Yamawuchi, Kazunobu; Kato, Ken; Naganawa, Shinji; Miao, Wei-jun",Impact of adjustment measures on reducing outpatient waiting time in a community hospital: application of a computer simulation.,Chinese medical journal,,0366-6999 0366-6999,,,"BACKGROUND: As an important determinant of patient satisfaction, waiting time, has gained increasing attention in the field of health care services. The present study aimed to illustrate the distribution characteristics of waiting time in a community hospital and explore the impact of potential measures to reduce outpatient waiting time based on a computer simulation approach. METHODS: During a one-month study period in 2006, a cross-sectional study was conducted in a community hospital located in Shanghai, China. Baseline data of outpatient waiting time were calculated according to the records of registration time and payment time. A simulation technique was adopted to investigate the impact of perspective reform methods on reducing waiting time. RESULTS: Data from a total of 10,092 patients and 26,816 medical consultations were collected in the study and 19,947 medical consultations were included. The average of the total visit time for outpatients in this hospital was 43.6 minutes in the morning, 19.1 minutes in the afternoon, and 34.3 minutes for the whole day studied period. The simulation results suggested that waiting time for outpatients could be greatly reduced through the introduction of appointment system and flexible demand-orientated doctor scheduling according to the numbers of patients waiting at different time of the workday. CONCLUSION: Adoption of an appointment system and flexible management of doctor scheduling may be effective way to achieve decreased waiting time.",05/03/2010,26/11/2018 12:52,14/04/2020 08:34,,574-580,,5,123,,Chin Med J (Engl),,,,,,,,eng,,,,,,,PMID: 20367984,,,,"Humans; Patient Satisfaction; Adult; Female; Male; Middle Aged; Aged; *Computer Simulation; Aged, 80 and over; Time Factors; Cross-Sectional Studies; Outpatients; 00; *Appointments and Schedules; Hospitals, Community; Review",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NNT59Q62,journalArticle,2010,"Milstein, Bobby; Homer, Jack; Hirsch, Gary",Analyzing national health reform strategies with a dynamic simulation model.,American journal of public health,,1541-0048 0090-0036,10.2105/AJPH.2009.174490,,"Proposals to improve the US health system are commonly supported by models that have only a few variables and overlook certain processes that may delay, dilute, or defeat intervention effects. We use an evidence-based dynamic simulation model with a broad national scope to analyze 5 policy proposals. Our results suggest that expanding insurance coverage and improving health care quality would likely improve health status but would also raise costs and worsen health inequity, whereas a strategy that also strengthens primary care capacity and emphasizes health protection would improve health status, reduce inequities, and lower costs. A software interface allows diverse stakeholders to interact with the model through a policy simulation game called HealthBound.",2010-05,26/11/2018 12:52,14/04/2020 08:34,,811-819,,5,100,,Am J Public Health,,,,,,,,eng,,,,,,,PMID: 20299653 PMCID: PMC2853627,,,,"*Health Policy; Humans; United States; Quality of Health Care; Health Care Costs; *Computer Simulation; *Models, Theoretical; System dynamics; Health Status Disparities; 1; Health Care Reform/*methods; Insurance Coverage; Insurance, Health; Preventive Medicine; Reimbursement Mechanisms; 220",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HSLCD6BE,journalArticle,2010,"Braithwaite, R. Scott; Omokaro, Cynthia; Justice, Amy C.; Nucifora, Kimberly; Roberts, Mark S.",Can broader diffusion of value-based insurance design increase benefits from US health care without increasing costs? Evidence from a computer simulation model.,PLoS medicine,,1549-1676 1549-1277,10.1371/journal.pmed.1000234,,"BACKGROUND: Evidence suggests that cost sharing (i.e.,copayments and deductibles) decreases health expenditures but also reduces essential care. Value-based insurance design (VBID) has been proposed to encourage essential care while controlling health expenditures. Our objective was to estimate the impact of broader diffusion of VBID on US health care benefits and costs. METHODS AND FINDINGS: We used a published computer simulation of costs and life expectancy gains from US health care to estimate the impact of broader diffusion of VBID. Two scenarios were analyzed: (1) applying VBID solely to pharmacy benefits and (2) applying VBID to both pharmacy benefits and other health care services (e.g., devices). We assumed that cost sharing would be eliminated for high-value services (<$100,000 per life-year), would remain unchanged for intermediate- or unknown-value services ($100,000-$300,000 per life-year or unknown), and would be increased for low-value services (>$300,000 per life-year). All costs are provided in 2003 US dollars. Our simulation estimated that approximately 60% of health expenditures in the US are spent on low-value services, 20% are spent on intermediate-value services, and 20% are spent on high-value services. Correspondingly, the vast majority (80%) of health expenditures would have cost sharing that is impacted by VBID. With prevailing patterns of cost sharing, health care conferred 4.70 life-years at a per-capita annual expenditure of US$5,688. Broader diffusion of VBID to pharmaceuticals increased the benefit conferred by health care by 0.03 to 0.05 additional life-years, without increasing costs and without increasing out-of-pocket payments. Broader diffusion of VBID to other health care services could increase the benefit conferred by health care by 0.24 to 0.44 additional life-years, also without increasing costs and without increasing overall out-of-pocket payments. Among those without health insurance, using cost saving from VBID to subsidize insurance coverage would increase the benefit conferred by health care by 1.21 life-years, a 31% increase. CONCLUSION: Broader diffusion of VBID may amplify benefits from US health care without increasing health expenditures.",16/02/2010,26/11/2018 12:52,14/04/2020 08:34,,e1000234,,2,7,,PLoS Med,,,,,,,,eng,,,,,,,PMID: 20169114 PMCID: PMC2821897,,,,"Humans; United States; *Computer Simulation; *Models, Theoretical; 1; Cost Sharing; Insurance, Health/*economics; Monte Carlo Simulation; 210",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 768Q2CLD,journalArticle,2010,"Cooley, Philip; Lee, Bruce Y.; Brown, Shawn; Cajka, James; Chasteen, Bernadette; Ganapathi, Laxminarayana; Stark, James H.; Wheaton, William D.; Wagener, Diane K.; Burke, Donald S.",Protecting health care workers: a pandemic simulation based on Allegheny County.,Influenza and other respiratory viruses,,1750-2659 1750-2640,10.1111/j.1750-2659.2009.00122.x,,"BACKGROUND AND OBJECTIVES: The Advisory Committee on Immunization Practices has identified health care workers (HCWs) as a priority group to receive influenza vaccine. Although the importance of HCW to the health care system is well understood, the potential role of HCW in transmission during an epidemic has not been clearly established. METHODS: Using a standard SIR (Susceptible-Infected-Recovered) framework similar to previously developed pandemic models, we developed an agent-based model (ABM) of Allegheny County, PA, that incorporates the key health care system features to simulate the spread of an influenza epidemic and its effect on hospital-based HCWs. FINDINGS: Our simulation runs found the secondary attack rate among unprotected HCWs to be approximately 60% higher (54.3%) as that of all adults (34.1%), which would result in substantial absenteeism and additional risk to HCW families. Understanding how a pandemic may affect HCWs, who must be available to treat infected patients as well as patients with other medical conditions, is crucial to policy makers' and hospital administrators' preparedness planning.",2010-03,26/11/2018 12:52,14/04/2020 08:34,,61-72,,2,4,,Influenza Other Respir Viruses,,,,,,,,eng,,,,,,,PMID: 20167046 PMCID: PMC2894576,,,,"Humans; Adult; Female; Male; Middle Aged; Young Adult; Aged; Child; Adolescent; Aged, 80 and over; Computer Simulation; Child, Preschool; Infant; *Health Personnel; Disease Outbreaks/*prevention & control; Infant, Newborn; Cross Infection/prevention & control/*transmission; Influenza Vaccines/administration & dosage/immunology; Influenza, Human/epidemiology/*prevention & control/transmission; Occupational Diseases/*prevention & control; Vaccination/*utilization; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FWAIKCEH,journalArticle,2010,"Plat, Marie-Christine J.; Frings-Dresen, Monique H. W.; Sluiter, Judith K.",Clinimetric quality of the fire fighting simulation test as part of the Dutch fire fighters Workers' Health Surveillance.,BMC health services research,,1472-6963 1472-6963,10.1186/1472-6963-10-32,,"BACKGROUND: Clinimetric data for the fire fighting simulation test (FFST), a new test proposed for the Workers' Health Surveillance (WHS) of Dutch fire fighters, were evaluated. METHODS: Twenty-one fire fighters took the FFST three times with one and three weeks between testing. Clinimetric quality was determined by means of reliability, agreement and validity. For reliability and agreement, the intraclass correlation coefficient (ICC), and standard error of measurement (SEM), were analysed. For construct validity, the tests from 45 fire fighters were correlated with their own and their supervisors' rated work ability. RESULTS: The ICCs were 0.56 and 0.79 at the one-week and three-week test-retest periods, respectively. Testing times ranged from 9 to 17 minutes; the SEMs were 70 s at the one-week and 40 s at the three-week test-retest periods. The construct validity was moderate (-0.47 < or = r < or = -0.33; p < 0.05). CONCLUSIONS: The FFST was reliable with acceptable agreement after three weeks. Construct validity was moderate. We recommend using FFST as a part of the WHS for Dutch fire fighters. It is advised that fire fighters should perform the FFST once as a trial before judging their performance in testing time during the second performance.",04/02/2010,26/11/2018 12:52,14/04/2020 08:35,,32,,,10,,BMC Health Serv Res,,,,,,,,eng,,,,,,,PMID: 20132538 PMCID: PMC2829551,,,,Humans; Netherlands; Reproducibility of Results; 00; *Occupational Health; *Fires; *Work Capacity Evaluation; Occupations; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PYBHJKRF,journalArticle,2010,"Harris, Julie N.; Hay, Jennifer; Kuniyuki, Alan; Asgari, Maryam M.; Press, Nancy; Bowen, Deborah J.",Using a family systems approach to investigate cancer risk communication within melanoma families.,Psycho-oncology,,1099-1611 1057-9249,10.1002/pon.1667,,"OBJECTIVE: The family provides an important communication nexus for information and support exchange about family cancer history, and adoption of family-wide cancer risk reduction strategies. The goals of this study were to (1) use the family systems theory to identify characteristics of this sample of families at increased risk of developing melanoma and (2) to relate familial characteristics to the frequency and style of familial risk communication. METHODS: Participants were first-degree relatives (n=313) of melanoma patients, recruited into a family web-based intervention study. We used multivariable logistic regression models to analyze the association between family functioning and family communication. RESULTS: Most participants were female (60%), with an average age of 51 years. Fifty percent of participants reported that they spoke to their relatives about melanoma risk and people were more likely to speak to their female family members. Familial adaptation, cohesion, coping, and health beliefs were strongly associated with an open style of risk communication within families. None were associated with a blocked style of risk communication. Only cohesion and adaptation were associated with the amount of risk communication that occurred within families. CONCLUSIONS: Overall, individuals who came from families that were more highly cohesive, adaptable, and shared strong beliefs about melanoma risk were more likely to communicate openly about melanoma. The fact that this association was not consistent across blocked communication and communication frequency highlights the multifaceted nature of this process. Future research should focus on the interplay between different facets of communication.",2010-10,26/11/2018 12:52,14/04/2020 08:34,,1102-1111,,10,19,,Psychooncology,,,,,,,,eng,"Copyright (c) 2010 John Wiley & Sons, Ltd.",,,,,,PMID: 20119933 PMCID: PMC2888971,,,,"Humans; Socioeconomic Factors; Adult; Female; Male; Middle Aged; Risk Factors; Aged; *Communication; Health Knowledge, Attitudes, Practice; Logistic Models; 00; Family/*psychology; Genetic Predisposition to Disease; Family Characteristics; *Family Relations; *Melanoma/genetics/prevention & control/psychology; *Skin Neoplasms/genetics/prevention & control/psychology; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9CNVZ5VN,journalArticle,2010,"Ritchie, Mark; Liedgens, Hiltrud; Nuijten, Mark",Cost effectiveness of a lidocaine 5% medicated plaster compared with pregabalin for the treatment of postherpetic neuralgia in the UK: a Markov model analysis.,Clinical drug investigation,,1173-2563 1173-2563,10.2165/11533310-000000000-00000,,"BACKGROUND: Published analyses have demonstrated that the lidocaine (lignocaine) plaster is a cost-effective treatment for postherpetic neuralgia (PHN) relative to gabapentin or pregabalin. However, these analyses have been based on indirect comparisons from placebo-controlled trials, and there is evidence of a discrepancy between the outcomes of direct and indirect analyses. Fortunately, recent publication of the results of a head-to-head trial comparing the lidocaine plaster and pregabalin in patients with PHN or diabetic polyneuropathy allows customization of the existing model to more accurately reflect the relative cost effectiveness of these two products. OBJECTIVE: To assess the cost-effectiveness of the lidocaine 5% medicated plaster compared with pregabalin for the treatment of PHN in the UK primary-care setting. METHODS: A Markov model has been developed to assess the costs and benefits of the lidocaine plaster and pregabalin over a",2010,26/11/2018 12:52,14/04/2020 08:35,,71-87,,2,30,,Clin Drug Investig,,,,,,,,eng,,,,,,,PMID: 20067326,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Markov Chains; Models, Statistical; United Kingdom; Delphi Technique; Data Interpretation, Statistical; 00; Administration, Topical; Analgesics/administration & dosage/*economics/*therapeutic use; Anesthetics, Local/administration & dosage/*economics/*therapeutic use; gamma-Aminobutyric Acid/administration & dosage/*analogs & derivatives/economics/therapeutic use; Lidocaine/administration & dosage/*economics/*therapeutic use; Neuralgia, Postherpetic/*drug therapy; Pregabalin; Probability Theory; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FH5B6D9V,journalArticle,2009,"Georgopoulos, Panos G.; Isukapalli, Sastry S.",A unified multiscale field/network/agent based modeling framework for human and ecological health risk analysis.,Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference,,1557-170X 1557-170X,10.1109/IEMBS.2009.5333795,,"A conceptual framework is presented for multi-scale field/network/agent-based modeling to support human and ecological health risk assessments. This framework is based on the representation of environmental dynamics in terms of interacting networks, agents that move across different networks, fields representing spatiotemporal distributions of physical properties, rules governing constraints and interactions, and actors that make decisions affecting the state of the system. Different deterministic and stochastic modeling case studies focusing on environmental exposures and associated risks are provided as examples, utilizing the bidirectional mapping between discrete, agent based approaches and continuous, equation based approaches. These examples include problems describing human health risk assessment, ecological risk assessment, and environmentally caused disease.",2009,26/11/2018 12:52,14/04/2020 08:34,,6420-6423,,,2009,,Conf Proc IEEE Eng Med Biol Soc,,,,,,,,eng,,,,,,,PMID: 19964423 PMCID: PMC3079376,,,,"Humans; Risk Factors; *Models, Statistical; Computer Simulation; Risk Assessment/*methods; *Health Status Indicators; *Artificial Intelligence; *Proportional Hazards Models; Environmental Exposure/*statistics & numerical data; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UY8KQAWQ,journalArticle,2009,"Pradelli, Lorenzo; Iannazzo, Sergio; Zaniolo, Orietta",The cost effectiveness and cost utility of valsartan in chronic heart failure therapy in Italy: a probabilistic markov model.,"American journal of cardiovascular drugs : drugs, devices, and other interventions",,1175-3277 1175-3277,10.2165/11315730-000000000-00000,,"To evaluate the cost effectiveness and cost utility of the use of valsartan in addition to standard therapy for the treatment of patients with chronic heart failure with low left ventricular ejection fraction (LVEF). The study was conducted by means of a cohort simulation based on a probabilistic Markov model and projecting the 23-month follow-up results of the Val-HeFT (Valsartan Heart Failure Trial) study over a 10-year time horizon. The model included four states (New York Heart Association [NYHA] classes II, III, IV, and death), and had a cycle duration of 1 month. Probabilistic simulations were performed using the WinBUGS software for Bayesian analysis. The distribution of patient parameters (sex, age, use of beta-adrenoceptor antagonists, and ACE inhibitors) in the simulated population were derived from the Italian heart failure patient population. Individual mortality data were derived from general mortality data by multiplying by a NYHA state-specific relative risk, while the probability of changing NYHA class was taken from the Val-HeFT data. Costs (2007 values) were calculated from the perspective of the Italian Health Service (IHS) and included costs for drugs and heart failure hospitalizations. Quality-of-life (QOL) weights were obtained by using published health-related QOL data for heart failure patients. A 3.5% annual discount rate was applied. Probabilistic sensitivity analysis was performed on each parameter using original-source 95% confidence interval (CI) values, or a +/-10% range when 95% CI values were unavailable. For the 10-year time horizon, patients were estimated to live for an average of 2.3 years or 1.7 quality-adjusted life-years (QALYs), with slight increases in the valsartan group. In this group, hospitalizations for worsening heart failure were predicted to be significantly reduced and overall treatment costs per patient to decrease by about and U20AC;550. In subgroup analyses, valsartan lost dominance in patients in NYHA II, and in those receiving beta-adrenoceptor antagonists or ACE inhibitors; the mean incremental cost-utility ratio for these groups was 21 240, 129 200, and 36 500 and U20AC;/QALY, respectively. Valsartan in addition to standard therapy is predicted to dominate standard therapy alone in Italian patients with mild to severe heart failure and low LVEF. There are relevant differences among various patient subgroups, and valsartan is expected to be good value for money particularly in the treatment of the most severe and less intensively treated (no ACE inhibitors, no beta-adrenoceptor antagonist) heart failure patients.",2009,26/11/2018 12:52,14/04/2020 08:35,,383-392,,6,9,,Am J Cardiovasc Drugs,,,,,,,,eng,,,,,,,PMID: 19929036,,,,"Humans; Quality-Adjusted Life Years; Female; Male; Middle Aged; Aged; Quality of Life; *Markov Chains; Drug Costs; Computer Simulation; Models, Statistical; Cost-Benefit Analysis/*methods; Age Factors; Hospital Costs; Italy; Sex Factors; 00; Antihypertensive Agents/*economics/therapeutic use; Chronic Disease/drug therapy/economics; Heart Failure/*drug therapy/*economics/mortality; Tetrazoles/*economics/therapeutic use; Valine/*analogs & derivatives/economics/therapeutic use; Valsartan; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PW733RIL,journalArticle,2010,"Jahn, Beate; Pfeiffer, Karl Peter; Theurl, Engelbert; Tarride, Jean-Eric; Goeree, Ron",Capacity constraints and cost-effectiveness: a discrete event simulation for drug-eluting stents.,Medical decision making : an international journal of the Society for Medical Decision Making,,1552-681X 0272-989X,10.1177/0272989X09336075,,"BACKGROUND: Waiting times for access to care, for example, for diagnostic imaging or surgery, are a highly relevant issue in health care. Waiting or deferred treatment caused by limited resource capacities can affect treatment success, quality of life, and costs. However, when treatment alternatives are compared in economic models, often unrestricted availability of resources is assumed, and dynamic changes in waiting lines remain unconsidered. The objective of this study was to evaluate the impact of potential real-world capacity restrictions and implied waiting lines on cost-effectiveness results and additional model outcomes. METHODS: A case study of drug-eluting and bare-metal stent treatment illustrates the effect of hypothetical capacity limitations of daily stenting procedures. Therefore, a decision-analytic model which allows for explicitly defined resource capacities and dynamic waiting lines was built using discrete event simulation. Cost-effectiveness, utilization, waiting time, and budgetary impact of alternative treatment scenarios are analyzed under the assumption of limited and unlimited resource capacities. RESULTS: The compared treatment allocation scenarios in the case study demonstrate that the additional cost for waiting increases the average treatment cost per patient. The different scenarios have different impacts on waiting lines because of the number of repeated interventions. Additionally, this effect leads to changes in cost-effectiveness results for the hypothetical capacity limit. Explicitly modeled capacities allow for further analysis of capacity utilization, waiting lines, and budgetary impact. CONCLUSION: Our model shows that neglected limited capacities can cause wrong cost-effectiveness results. Therefore, capacities should be explicitly included in decision-analytic models if there is evidence of scarcity.",2010-02,26/11/2018 12:52,14/04/2020 08:34,,16-28,,1,30,,Med Decis Making,,,,,,,,eng,,,,,,,PMID: 19789389,,,,"Humans; Waiting Lists; Cost-Benefit Analysis; Decision Making; *Models, Theoretical; *Health Services Accessibility; 00; *Resource Allocation; Drug-Eluting Stents/*economics/utilization; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RJG8C3RD,journalArticle,2009,"Manasse, Henri R. Jr",2009 Rho Chi Lecture: interdisciplinary health professions education: a systems approach to bridging the gaps.,American journal of pharmaceutical education,,1553-6467 0002-9459,,,,28/08/2009,26/11/2018 12:52,14/04/2020 08:34,,90,,5,73,,Am J Pharm Educ,,,,,,,,eng,,,,,,,PMID: 19777681 PMCID: PMC2739073,,,,"Humans; United States; Clinical Competence; Leadership; Patient Care Team/*organization & administration; *Cooperative Behavior; Medical Errors/*prevention & control; Accreditation; Health Care Reform; Total Quality Management/*organization & administration; Certification; 00; Delivery of Health Care, Integrated/*organization & administration; Health Occupations/*education; *Organizational Objectives; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, UP5J5JAA,journalArticle,2009,"Tuulonen, Anja; Salminen, Hannu; Linna, Miika; Perkola, Markku",The need and total cost of Finnish eyecare services: a simulation model for,Acta ophthalmologica,,1755-3768 1755-375X,10.1111/j.1755-3768.2009.01532.x,,"PURPOSE: The aims of this study were: (i) to create a structural simulation model capable of predicting the future need and cost of eyecare services in Finland; and (ii) to test and rank different policy alternatives for access to care and the required physician workforce. METHODS: Using the system dynamics approach, the number and cost of patients with cataract, glaucoma, diabetic retinopathy and age-related macular degeneration (AMD) were described with causal-loop diagrams and were then translated into a set of mathematical equations to build a computer simulation model. Mathematically, the problem was formulated as a set of differential equations that were solved numerically with specialized software. The validity of the model was tested against prevalence and administrative historical data. The costs covered by the public sector in Finland were obtained from 2003 from the Finnish Hospital Discharge Register (including outpatient care), the Finnish Social Insurance Institution and a survey of hospital price lists. Different levels of access to public care were then simulated in four eye diseases, for which the model estimated the need for services and resources and their costs in the years 2005-2040. RESULTS: The model forecasted that the adoption of the 2005 national 'access to care' criteria for cataract surgery would shorten waiting lists. If the workload of Finnish ophthalmologists were kept at the 2003 level, the graduation rate of new ophthalmologists would have to increase by 75% from the current level. If all glaucoma patients were followed in the public sector in future, even this increase in training would not meet the demand for physician workforce. The current model indicated that the screening frequency of diabetes can be increased without large sacrifices in terms of costs. AMD therapy has a significant role in the allocation of future resources in eyecare. The modelling study predicted that ageing alone will increase the costs of eyecare during the next four decades in Finland by about 1% per year in real terms (undiscounted and without inflation of unit costs). The increases in total yearly costs were on average 8.6% between 2001 and 2003. CONCLUSIONS: The results of this modelling study indicate that policy initiatives, such as defining criteria for access to care, can have substantial implications on the demand for care and waiting times whereas the effect of ageing alone was relatively small. Measures to control several other factors - such as the adoption and price level of new technologies, treatments and practice patterns - will be at least equally important in order to restrain healthcare costs effectively.",2009-11,26/11/2018 12:52,14/04/2020 08:35,,820-829,,8,87,,Acta Ophthalmol,,,,,,,,eng,,,,,,,PMID: 19740130,,,,"Humans; Health Services Accessibility; *Models, Economic; *Health Care Costs; Computer Simulation; *Models, Organizational; Finland; 00; *Health Services Needs and Demand; Ophthalmology/*economics; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ZS4JX55J,journalArticle,2010,"Lawson, K. D.; Fenwick, E. A. L.; Pell, A. C. H.; Pell, J. P.","Comparison of mass and targeted screening strategies for cardiovascular risk: simulation of the effectiveness, cost-effectiveness and coverage using a cross-sectional survey of 3921 people.",Heart (British Cardiac Society),,1468-201X 1355-6037,10.1136/hrt.2009.177204,,"BACKGROUND: Cardiovascular primary prevention should be targeted at those with the highest global risk. However, it is unclear how best to identify such individuals from the general population. The aim of this study was to compare mass and targeted screening strategies in terms of effectiveness, cost effectiveness and coverage. METHODS: The Scottish Health Survey provided cross-sectional data on 3921 asymptomatic members of the general population aged",2010-02,26/11/2018 12:52,14/04/2020 08:34,,208-212,,3,96,,Heart,,,,,,,,eng,,,,,,,PMID: 19737737,,,,"Humans; Cost-Benefit Analysis; Adult; Female; Male; Middle Aged; Aged; Risk Assessment; Models, Economic; Cross-Sectional Studies; Mass Screening/economics/*methods; Cardiovascular Diseases/economics/*prevention & control; 00; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, E7BGLNLA,journalArticle,2010,"Harder, B. Nicole",Use of simulation in teaching and learning in health sciences: a systematic review.,The Journal of nursing education,,0148-4834 0148-4834,10.3928/01484834-20090828-08,,"The use of simulation as an educational tool is becoming increasingly prevalent in health care practice. Institutions have adopted simulations to help educate their students and health care professionals; however, intervention effectiveness evaluation continues to be an area requiring research. With use of this technology, it has become necessary to evaluate this method of educating health care professionals. As simulation use has increased, so has the literature related to evaluation of the innovative teaching method. A systematic review of the literature examined the effectiveness of simulation as a teaching tool. The aim was to evaluate current literature on the use of clinical simulation in health care education. The findings identify themes in the evaluation literature, highlight gaps in the literature as it pertains to evaluating the effectiveness of using simulations as a teaching tool, and support the need for further research into the evaluation of simulation as a teaching tool.",2010-01,26/11/2018 12:52,14/04/2020 08:34,,23-28,,1,49,,J Nurs Educ,,,,,,,,eng,"Copyright 2010, SLACK Incorporated.",,,,,,PMID: 19731886,,,,"Humans; Nursing Education Research; Computer Simulation; Patient Care Team; *Clinical Competence; Research Design; Evaluation Studies as Topic; Education, Nursing/*methods; Models, Educational; Attitude of Health Personnel; Teaching/*methods; *Manikins; Computer-Assisted Instruction/*methods; 00; Self Efficacy; Education, Medical/*methods; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 65PYJ2IJ,journalArticle,2009,"Haycox, Alan; Armand, Christophe; Murteira, Susana; Cochran, John; Francois, Clement",Cost effectiveness of rasagiline and pramipexole as treatment strategies in early Parkinson's disease in the UK setting: an economic Markov model evaluation.,Drugs & aging,,1179-1969 1170-229X,10.2165/11316770-000000000-00000,,"BACKGROUND: Levodopa is the most effective treatment for the symptoms of Parkinson's disease (PD). However, after an initial period of benefit, several limitations become apparent, including motor complications such as dyskinesia. Dyskinesia can severely affect patients' quality of life and increases healthcare resource use. Thus, delaying the need for levodopa, and therefore the onset of levodopa-induced dyskinesia, is important. OBJECTIVE: The aim of this study was to compare the cost effectiveness, from a UK healthcare payer perspective, of two antiparkinsonian treatment strategies in early PD: first-line monotherapy with rasagiline, a novel monoamine oxidase B inhibitor; and the non-ergoline dopamine receptor agonist pramipexole. METHODS: An economic Markov model was developed as a pragmatic tool to derive comparative information on the effectiveness, utility and costs of these two strategies over a 5-year period. Model input data were obtained from the TEMPO study for rasagiline and from a study by the Parkinson Study Group for pramipexole. Effectiveness outcomes were time to levodopa and time to levodopa-induced dyskinesia. Cost and quality-adjusted life-year (QALY) data were derived from published sources. RESULTS: Rasagiline was the dominant strategy. Compared with pramipexole, use of the rasagiline strategy was estimated to reduce costs by 18% per patient over 5 years and was associated with an additional 10% delay in dyskinesia onset (0.41 years; 95% CI 0.27, 0.55). This strategy was also found to prolong the time to levodopa initiation by 25% through a gain of 0.83 levodopa-free years (95% CI 0.56, 1.1). In addition, use of the rasagiline strategy was found to generate a 5% gain in QALYs over 5 years compared with the pramipexole strategy (3.7 +/- 0.02 vs 3.51 +/- 0.03). Sensitivity analyses confirmed that the model was robust. CONCLUSIONS: Rasagiline represents a cost-effective alternative to pramipexole in the treatment of early PD in the UK.",2009,26/11/2018 12:52,14/04/2020 08:34,,791-801,,9,26,,Drugs Aging,,,,,,,,eng,,,,,,,PMID: 19728752,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Treatment Outcome; Female; Male; Middle Aged; Aged; Markov Chains; *Health Care Costs; Monte Carlo Method; United Kingdom; Models, Economic; State Medicine; Disease Progression; Probability; Clinical Trials as Topic; 00; Indans/*economics/therapeutic use; Antiparkinson Agents/*economics/therapeutic use; Benzothiazoles/*economics/therapeutic use; Dopamine Agonists/economics/therapeutic use; Insurance, Health, Reimbursement; Monoamine Oxidase Inhibitors/economics/therapeutic use; Parkinson Disease/*drug therapy/economics/prevention & control; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Z9SVVLTQ,journalArticle,2009,"Annemans, Lieven; Nackaerts, Kristiaan; Bartsch, Pierre; Prignot, Jacques; Marbaix, Sophie","Cost effectiveness of varenicline in Belgium, compared with bupropion, nicotine replacement therapy, brief counselling and unaided smoking cessation: a BENESCO Markov cost-effectiveness analysis.",Clinical drug investigation,,1173-2563 1173-2563,10.2165/11317730-000000000-00000,,"BACKGROUND AND OBJECTIVE: Varenicline is a nicotinic acetylcholine receptor partial agonist that is approved for use as an aid to smoking cessation. Randomized clinical trials show that its efficacy is superior to that of other current smoking cessation therapies. This study set out to determine the cost effectiveness of varenicline relative to other smoking cessation interventions (bupropion and nicotine replacement therapy [NRT]) as well as brief counselling alone and unaided cessation in a cohort of Belgian adult smokers making a one-time quit attempt, from the perspective of the healthcare payer (public and private). METHODS: A Markov model, the Benefits of Smoking Cessation on Outcomes (BENESCO) model, was applied to calculate the long-term health and economic benefits of smoking cessation. Cost effectiveness was expressed as cost per life-year (LY) gained and cost per quality-adjusted life-year (QALY) gained. Clinical and economic model inputs were obtained from the literature and public healthcare databases. Costs were discounted at 3% and health outcomes at 1.5%. A probabilistic sensitivity analysis and a one-way sensitivity analysis were performed to test the robustness of the results. RESULTS: Varenicline is associated with a reduction of smoking-related morbidity and mortality as well as with a decrease in healthcare costs compared with the pharmacological agents bupropion and NRT. Varenicline also leads to additional LYs and QALYs compared with brief counselling alone and unaided cessation over a lifetime period. Varenicline is a dominant strategy compared with bupropion and NRT. Compared with brief counselling alone and unaided cessation, varenicline presents a cost/QALY of euro240 and euro1656, respectively. CONCLUSION: Varenicline is a cost-effective alternative to brief counselling and unaided cessation, and is a cost-saving treatment in comparison with bupropion and NRT, in a Belgian population of smokers willing to quit.",2009,26/11/2018 12:52,14/04/2020 08:34,,655-665,,10,29,,Clin Drug Investig,,,,,,,,eng,,,,,,,PMID: 19715382,,,,"Humans; Cost-Benefit Analysis; Treatment Outcome; Adult; Female; Male; Middle Aged; Young Adult; Aged; Markov Chains; Adolescent; Computer Simulation; Models, Statistical; Recurrence; Age Factors; 00; Belgium; Varenicline; Antidepressive Agents, Second-Generation/*economics/*therapeutic use; Benzazepines/*economics/*therapeutic use; Bupropion/*economics/*therapeutic use; Counseling/*economics; Nicotine/*economics/*therapeutic use; Nicotinic Agonists/*economics/*therapeutic use; Quinoxalines/*economics/*therapeutic use; Smoking Cessation/*economics; Smoking/epidemiology/mortality; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2P9BTFQV,journalArticle,2009,"Fajutrao, Liberty; Paulsson, Bjorn; Liu, Sherry; Locklear, Julie",Cost-effectiveness of quetiapine plus mood stabilizers compared with mood stabilizers alone in the maintenance therapy of bipolar I disorder: results of a Markov model analysis.,Clinical therapeutics,,1879-114X 0149-2918,10.1016/j.clinthera.2009.06.009,,"OBJECTIVE: The aim of this study was to estimate the following: (1) the number of acute mood events prevented by adjunctive quetiapine therapy, and the potential cost savings; (2) the number of acute mood event-associated hospitalizations avoided by using adjunctive quetiapine therapy, and the potential cost savings of this intervention; and (3) the economic value of adjunctive quetiapine therapy in the maintenance treatment of bipolar I disorder. METHODS: A Markov model was developed to simulate the transitions of newly stabilized adult patients with bipolar I disorder across 4 possible health states: euthymia, acute mania, acute depression, and discontinued/ no active therapy. Clinical data were obtained from 2 randomized, double-blind, Phase III trials of up to 2 years' duration (D1447C00126 and D1447C00127) that evaluated the efficacy and tolerability of quetiapine (versus placebo) when coadministered with lithium or valproate in increasing the time to recurrence of acute mood events in patients with bipolar I disorder. The model evaluated clinical and economic outcomes in 8 quarterly cycles (24 months). Outcome measures included the number of acute mood events, number of hospitalizations related to acute mood events, and their costs. Quality-adjusted life-years (QALYs) were calculated as a secondary outcome. The model was conducted from the perspective of the UK National Health Service, base year 2007. RESULTS: In the model analysis, adjunctive quetiapine with lithium or valproate was associated with a 54% reduction in the occurrence of acute mood events, a 29% reduction in acute mood event-related hospitalization costs, and a 4% improvement in QALY gains, with 5% lower total direct costs than placebo + lithium/valproate. The incremental cost-effectiveness ratios (in year-2007 pound) were 506 per additional acute mood event avoided, 4261 per additional acute mood event-related hospitalization prevented, and -7453 per additional QALY gained. The sensitivity analyses indicated that these results were robust. CONCLUSIONS: The results of this Markov model with a 2-year time horizon suggest that adjunctive quetiapine and mood-stabilizer therapy with lithium or valproate, compared with mood-stabilizer therapy alone in the maintenance treatment of patients with bipolar I disorder, were associated with fewer acute mood events, fewer acute mood event-related hospitalizations, and lower total costs, thereby improving patient mental health outcomes and minimizing impact on payer budgets, from the perspective of the UK National Health Service.",2009-06,26/11/2018 12:52,14/04/2020 08:34,,1456-1468,,,31 Pt 1,,Clin Ther,,,,,,,,eng,,,,,,,PMID: 19698903,,,,Humans; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; *Cost-Benefit Analysis; *Markov Chains; Health Status; 00; Affect/*drug effects; Antipsychotic Agents/economics/*therapeutic use; Benzodiazepines/administration & dosage/pharmacology; Bipolar Disorder/*drug therapy; Dibenzothiazepines/economics/*therapeutic use; Double-Blind Method; Fluoxetine/administration & dosage/pharmacology; Quetiapine Fumarate; Valproic Acid/administration & dosage/pharmacology; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VM7QNEZC,journalArticle,2009,"Forsythe, Lydia","Action research, simulation, team communication, and bringing the tacit into voice society for simulation in healthcare.",Simulation in healthcare : journal of the Society for Simulation in Healthcare,,1559-2332 1559-2332,10.1097/SIH.0b013e3181986814,,"BACKGROUND: In healthcare, professionals usually function in a time-constrained paradigm because of the nature of care delivery functions and the acute patient populations usually in need of emergent and urgent care. This leaves little, if no time for team reflection, or team processing as a collaborative action. Simulation can be used to create a safe space as a structure for recognition and innovation to continue to develop a culture of safety for healthcare delivery and patient care. METHODS: To create and develop a safe space, three qualitative modified action research institutional review board-approved studies were developed using simulation to explore team communication as an unfolding in the acute care environment of the operating room. An action heuristic was used for data collection by capturing the participants' narratives in the form of collaborative recall and reflection to standardize task, process, and language. RESULTS: During the qualitative simulations, the team participants identified and changed multiple tasks, process, and language items. The simulations contributed to positive changes for task and efficiencies, team interactions, and overall functionality of the team. CONCLUSION: The studies demonstrated that simulation can be used in healthcare to define safe spaces to practice, reflect, and develop collaborative relationships, which contribute to the realization of a culture of safety.",2009,26/11/2018 12:52,14/04/2020 08:34,,143-148,,3,4,,Simul Healthc,,,,,,,,eng,,,,,,,PMID: 19680080,,,,"Humans; Clinical Competence; Health Personnel/education; *Models, Theoretical; *Interdisciplinary Communication; Patient Care Team/*standards; *Health Services Research; 00; Teaching/methods; Operating Rooms; Practice (Psychology); 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, U65PVGYX,journalArticle,2009,"Jankovic, Slobodan M.; Kostic, Marina; Radosavljevic, Marija; Tesic, Danka; Stefanovic-Stoimenov, Natasa; Stevanovic, Ivan; Rakovic, Sladana; Aleksic, Jelena; Folic, Marko; Aleksic, Aleksandra; Mihajlovic, Ivana; Biorac, Nenad; Borlja, Jelena; Vuckovic, Radosava",Cost-effectiveness of four immunomodulatory therapies for relapsing-remitting multiple sclerosis: a Markov model based on data a Balkan country in socioeconomic transition.,Vojnosanitetski pregled,,0042-8450 0042-8450,,,"BACKGROUND/AIM: A cost-effectiveness analyses of immunomodulatory treatments for relapsing-remitting multiple sclerosis (RRMS) in developed countries have shown that any benefit from these drugs is achieved at very high cost. The aim of our study was to compare the cost-effectiveness of five treatment strategies in patients diagnosed with RRMS (symptom management alone and in combination with subcutaneous glatiramer acetate, intramuscular interferon beta-1a, subcutaneous interferon beta-1a, or intramuscular interferon [beta-1b) in a Balkan country in socio-economic transition. METHODS: The Markov model was developed based on the literature about effectiveness and on local Serbian cost calculations. The duration of a cycle in the model was set to a month. The baseline time horizon was 480 months (40 years). The societal perspective was used for costs and outcomes, and they were discounted for 3% annually. Monte Carlo micro simulation with 1000 virtual patients was done. RESULTS: Significant gain with immunomodulatory therapy was achieved only in relapse-free years, while the time spent in health states EDSS 0.0-5.5 was longer with symptomatic therapy only, and gains in life years and QALYs were only marginal. One QALY gained costs more than a billion of Serbian dinars (more than 20 million US dollars), making each of the four immunomodulatory therapies cost-ineffective. CONCLUSION: Our study suggests that immunomodulatory therapy of RRMS in a Balkan country in socioeconomic transition is not cost-effective, regardless of the type of the therapy. Moderate gain in relapse-free years does not translate to gain in QALYs, probably due to adverse effects of immunomodulatory therapy.",2009-07,26/11/2018 12:52,14/04/2020 08:34,,556-562,,7,66,,Vojnosanit Pregl,,,,,,,,eng,,,,,,,PMID: 19678581,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Markov Chains; Drug Costs; Serbia; 00; Adjuvants, Immunologic/*administration & dosage/*economics; Glatiramer Acetate; Interferon beta-1a; Interferon beta-1b; Interferon-beta/*administration & dosage/*economics; Multiple Sclerosis, Relapsing-Remitting/*drug therapy/*economics; Peptides/*administration & dosage/economics; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NU8AFZES,journalArticle,2009,"Ramwadhdoebe, Sabrina; Buskens, Erik; Sakkers, Ralph J. B.; Stahl, James E.",A tutorial on discrete-event simulation for health policy design and decision making: optimizing pediatric ultrasound screening for hip dysplasia as an illustration.,"Health policy (Amsterdam, Netherlands)",,1872-6054 0168-8510,10.1016/j.healthpol.2009.07.007,,"BACKGROUND: It is increasingly recognized that healthcare is a complex system with limited resources and many interacting sources of both positive and negative feedback. Discrete-event simulation (DES) is a tool that readily accommodates questions of capacity planning, throughput management and interacting resources. As a result the use of DES in informing healthcare decision making is increasing. However, understanding when and how to build a DES model and use it for policy making is not yet a common knowledge. METHODS: The steps in building a DES model will be demonstrated using a real-world example, i.e., pediatric ultrasound screening for hip dysplasia. The main components of a DES model such as entities, resources and queues will be introduced and we will examine questions such as referral schedule, number of ultrasound machines and type of screeners and how these entities interact. Finally a review of the statistical techniques appropriate to DES will be provided. CONCLUSION: Discrete-event simulation is a valuable tool in the policymakers armentarium. It can be used effectively to analyze and understand complex healthcare systems and policy problems such as population screening.",2009-12,26/11/2018 12:52,14/04/2020 08:34,,143-150,,02-Mar,93,,Health Policy,,,,,,,,eng,,,,,,,PMID: 19674809,,,,"*Health Policy; Humans; Pediatrics; *Models, Theoretical; Infant; *Operations Research; *Decision Making; Mass Screening/*methods; 1; Hip Dislocation, Congenital/diagnosis/*diagnostic imaging; Regional Health Planning; Ultrasonography; Discrete event; Align resources with patient and population; X",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3ICZD7A2,journalArticle,2009,"Reeler, Anne; Qiao, Youlin; Dare, Lola; Li, Jing; Zhang, Ai-Li; Saba, Joseph",Women's cancers in developing countries: from research to an integrated health systems approach.,Asian Pacific journal of cancer prevention : APJCP,,2476-762X 1513-7368,,,"The article focuses on two women's cancers, breast and cervical cancer, that are much more deadly in developing countries than in developed countries. Early detection can make a significant difference for the treatment outcome of these two cancers and there are now cost-effective tools for prevention and screening. The authors propose a new public health approach to these two cancers in developing countries where resources for effective cancer control are very limited and offer a framework for putting women's cancers in developing countries on the global public health agenda. The key areas are: 1. Proposals for a new, integrated public health approach to women's cancers (breast and cervical) in resource poor settings; 2. Reviews of the evidence for cost-effective screening and early detection of breast and cervical cancer, and discussion of some of the lessons learned from HIV/AIDS on an integrated health systems approach; 3. Outlines of ways to make a priority of women?s cancers in developing countries on the political agenda of international agencies.",2009-09,26/11/2018 12:52,14/04/2020 08:35,,519-526,,3,10,,Asian Pac J Cancer Prev,,,,,,,,eng,,,,,,,PMID: 19640202,,,,Humans; Female; *Developing Countries; Women's Health; 00; *Biomedical Research; *Breast Neoplasms/diagnosis/therapy; *Ovarian Neoplasms/diagnosis/therapy; *Uterine Cervical Neoplasms/diagnosis/therapy; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9AX4RZXQ,journalArticle,2009,"Winkelman, Chris",Bed rest in health and critical illness: a body systems approach.,AACN advanced critical care,,1559-7776 1559-7768,10.1097/NCI.0b013e3181ac838d,,"Bed rest is a common intervention for critically ill adults. Associated with both benefits and adverse effects, bed rest is undergoing increasing scrutiny as a therapeutic option in the intensive care unit. Bed rest has molecular and systemic effects, ultimately affecting functional outcomes in healthy individuals as well as in those with acute and critical illnesses. Using empirical sources, the purpose of this article was to describe the consequences of bed rest and immobility, especially consequences with implications for critically ill adults in the intensive care unit. This review uses body systems to cluster classic and current results of bed rest studies, beginning with cardiovascular and including pulmonary, renal, skin, nervous, immune, gastrointestinal/ metabolic, and skeletal systems. It concludes with effects on muscles, a system profoundly affected by immobility and bed rest.",2009-09,26/11/2018 12:52,14/04/2020 08:35,,254-266,,3,20,,AACN Adv Crit Care,,,,,,,,eng,,,,,,,PMID: 19638747,,,,Humans; Empirical Research; *Bed Rest; *Critical Illness; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WU68RWGL,journalArticle,2009,"Kameg, Kirstyn; Mitchell, Ann M.; Clochesy, John; Howard, Valerie M.; Suresky, Jane",Communication and human patient simulation in psychiatric nursing.,Issues in mental health nursing,,1096-4673 0161-2840,10.1080/01612840802601366,,"Communication is an integral component of nursing education and has been shown to improve health outcomes, patient compliance, and patient satisfaction. Psychiatric nursing emphasizes knowledge and utilization of communication skills. Nursing students often express anxiety and lack of confidence regarding communicating with patients diagnosed with psychiatric illnesses. Human patient simulation is one method that may be used for students to practice and become proficient with communication skills in a simulated environment. The authors of this article provide an overview of communication and psychiatric nursing as well as review of the current research related to the use of human patient simulation in nursing education.",2009-08,26/11/2018 12:52,14/04/2020 08:34,,503-508,,8,30,,Issues Ment Health Nurs,,,,,,,,eng,,,,,,,PMID: 19591024,,,,"Humans; Clinical Competence; Nursing Education Research; *Patient Simulation; Curriculum; Safety; Education, Nursing, Baccalaureate/*methods; Attitude of Health Personnel; Career Choice; Students, Nursing/psychology; *Nurse-Patient Relations; 00; Self Efficacy; Teaching/methods; *Communication Barriers; Anxiety/prevention & control/psychology; Fear; Psychiatric Nursing/*education/organization & administration; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2YTMPK73,journalArticle,2009,"Edwards, Roger A.; Graham, Alan; Williams, Melissa; Amati, Mike; Wright, Caroline; Lee, Mei; Walsh, Dan; Hughes, Nick",Quantifying a strategic view of diabetes technology impacts: a system dynamics approach.,Diabetes technology & therapeutics,,1520-9156 1520-9156,10.1089/dia.2008.0089,,"BACKGROUND: Diabetes and its related complications and comorbidities (C&Cs) represent a significant and increasing healthcare burden. Absence of a systematic manner to evaluate value propositions of technologies from various stakeholders' perspectives impedes the best uses of current and emerging technologies. METHODS: A system dynamics methodology was used to develop a comprehensive causal simulator of the U.S. population and give proof of principle that entire portfolios of present and future technologies can be evaluated for direct and indirect impacts. An explicit semiquantitative methodology was used for surveying, prioritizing, and grouping C&Cs, patient subgroups, and technologies, utilizing diverse publicly available clinical literature. RESULTS: The resulting model simulates the incidence and prevalence of diabetes and 10 of its most commonly associated C&Cs, reflecting their interrelated upstream and downstream relationships. The simulator enables systematic evaluation of tens of thousands of potential combinations of emerging technologies and technology leverage points that can be used to improve patient outcomes and guide technology investments. Feasibility was demonstrated through single, pair-wise, and targeted analyses of technologies. CONCLUSIONS: This effort demonstrated the feasibility of linking complex, interconnected disease states, impact points, outcomes, and interventions with a variety of outcome metrics, to an extent greater than existing models developed for other purposes. The project demonstrated the ability to identify priority technologies and pipeline therapies and leverage points among diabetes interventions. It demonstrated more effective knowledge management of diverse information essential for formulating strategy that could be applied in a wide range of therapeutic applications and technology innovation uses.",2009-07,26/11/2018 12:52,14/04/2020 08:34,,411-418,,7,11,,Diabetes Technol Ther,,,,,,,,eng,,,,,,,PMID: 19580353,,,,"Humans; United States/epidemiology; Cost of Illness; System dynamics; Prevalence; Ethnic Groups; 1; Coronary Disease/epidemiology; Diabetes Complications/economics/epidemiology/*therapy; Diabetes Mellitus, Type 2/economics/*epidemiology/therapy; Diabetes Mellitus/economics/epidemiology/*therapy; Diabetic Angiopathies/epidemiology; Technology/*trends; 320",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4XAW2986,journalArticle,2009,"Dukic, Vanja M.; Niessner, Marina; Pickett, Kate E.; Benowitz, Neal L.; Wakschlag, Lauren S.",Calibrating self-reported measures of maternal smoking in pregnancy via bioassays using a Monte Carlo approach.,International journal of environmental research and public health,,1660-4601 1660-4601,10.3390/ijerph6061744,,"Maternal smoking during pregnancy is a major public health problem that has been associated with numerous short- and long-term adverse health outcomes in offspring. However, characterizing smoking exposure during pregnancy precisely has been rather difficult: self-reported measures of smoking often suffer from recall bias, deliberate misreporting, and selective non-disclosure, while single bioassay measures of nicotine metabolites only reflect recent smoking history and cannot capture the fluctuating and complex patterns of varying exposure of the fetus. Recently, Dukic et al. have proposed a statistical method for combining information from both sources in order to increase the precision of the exposure measurement and power to detect more subtle effects of smoking. In this paper, we extend the Dukic et al. method to incorporate individual variation of the metabolic parameters (such as clearance rates) into the calibration model of smoking exposure during pregnancy. We apply the new method to the Family Health and Development Project (FHDP), a small convenience sample of 96 predominantly working class white pregnant women oversampled for smoking. We find that, on average, misreporters smoke 7.5 cigarettes more than what they report to smoke, with about one third underreporting by 1.5, one third under-reporting by about 6.5, and one third underreporting by 8.5 cigarettes. Partly due to the limited demographic heterogeneity in the FHDP sample, the results are similar to those obtained by the deterministic calibration model, whose adjustments were slightly lower (by 0.5 cigarettes on average). The new results are also, as expected, less sensitive to assumed values of cotinine half-life.",2009-06,26/11/2018 12:52,14/04/2020 08:34,,1744-1759,,6,6,,Int J Environ Res Public Health,,,,,,,,eng,,,,,,,PMID: 19578458 PMCID: PMC2705215,,,,Humans; Adult; Female; Monte Carlo Method; Pregnancy; Sensitivity and Specificity; *calibration; 00; Case-Control Studies; *Self Disclosure; *bioassay; *self-report; *smoking; *Smoking; Biological Assay/*methods; Calibration; Pregnancy Complications/*diagnosis; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JDQ2ZXU8,journalArticle,2009,"Washington, Michael L.",Evaluating the capability and cost of a mass influenza and pneumococcal vaccination clinic via computer simulation.,Medical decision making : an international journal of the Society for Medical Decision Making,,0272-989X 0272-989X,10.1177/0272989X09333126,,"OBJECTIVE: To determine if a mass influenza/pneumococcal vaccination clinic could vaccinate 15,000 clients in 17 h; optimize personnel configuration to maximize number of clients vaccinated; and estimate costs (opportunity and clinic) and revenue. METHOD: The author used a discrete event simulation model to estimate the throughput of the vaccination clinic as the number of clients (arrival intensity) increased and as staff members were reassigned to different workflows. We represented workflows for 3 client types: ""Medicare,'' ""Special,'' and ""Cash,'' where ""Special'' designates Medicare clients who needed assistance moving through the clinic. The costs of supplies, staff sal-aries, and client waiting time were included in the model. We compared the ""original'' model based on the staffing and performance of an actual clinic to an ;;optimized'' model in which staff were reassigned to optimize number of clients vaccinated. RESULTS: A maximum of 13,138 and 15,094 clients in the original and optimized models, respectively, were vaccinated. At the original arrival rate (8300 clients vaccinated in 17 h), supplies cost about $191,000 and were the most expensive component of the clinic operation in both models. However, as the arrival intensity increased to 140%, the ""Medicare'' client opportunity cost increased from $23,887 and $21,474 to $743,510 and $740,760 for the simulated original and optimized models, respectively. CONCLUSION: The clinic could reach their target of 15,000 vaccinees with 2 fewer staff members by rearranging staff assignments from ""Special"" to ""Medicare'' and ""Cash'' stations. Computer simulation can help public health officials determine the most efficient use of staff, machinery, supplies, and time.",2009-08,26/11/2018 12:52,14/04/2020 08:35,,414-423,,4,29,,Med Decis Making,,,,,,,,eng,,,,,,,PMID: 19564434,,,,"Humans; United States; Health Care Costs; Models, Theoretical; Public Health; Models, Economic; discrete event simulation; 1; Computer Simulation/*economics/statistics & numerical data; Disaster Planning/*economics/statistics & numerical data; Immunization/statistics & numerical data; Influenza Vaccines/*economics; Influenza, Human/economics/*prevention & control; Medicare/statistics & numerical data; Pneumococcal Infections/economics/*prevention & control; Pneumococcal Vaccines/*economics; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GWFSUA6H,journalArticle,2009,"Sakurai, Yasuyoshi; Uchida, Michiko; Aiba, Junko; Mimura, Fumiaki","[Simulation of obstetrical disseminated intravascular coagulation (DIC) by scoring algorithm criteria established by the Japanese Association for Acute Medicine, the revised Japanese Ministry of Health and Welfare criteria and the International Society on Thrombosis and Haemostasis criteria].",Masui. The Japanese journal of anesthesiology,,0021-4892 0021-4892,,,"BACKGROUND: Although obstetric disease is one of the major causes of disseminated intravascular coagulation (DIC), no gold standard exists. Three current criteria, the Japanese Association for Acute Medicine (JAAM) -DIC criteria, the revised Japanese Ministry of Health and Welfare (JMHW) criteria and the International Society on Thrombosis and Haemostasis (ISTH) criteria, do not clarify the usefulness in obstetric DIC. We therefore conducted a retrospective study by simulation. METHODS: We enrolled 89 cases of emergent caesarean section when platelet count decreased to below 150,000 x 10(9) x mm(-3) during 7 days from 3 days before operation to 3 days after operation from April 2004 to March 2007. We applied them and compared diagnostic rates and investigated characteristics of obstetric DIC. RESULTS: After excluding 21 cases, 68 cases were examined. The number of patients diagnosed with DIC by JAAM-DIC criteria, JMHW criteria and ISTH criteria were 15 (22.1%), 5 (7.4%) and 3 (4.4%), respectively. Fifteen patients who fulfilled JAAM-DIC criteria included all 5 patients for whom DIC was diagnosed by JMHW criteria, and those 5 patients included all 3 patients for whom DIC was diagnosed by ISTH criteria. CONCLUSIONS: The current study indicates that",2009-06,26/11/2018 12:52,14/04/2020 08:35,,732-738,,6,58,,Masui,,,,,,,,jpn,,,,,,,PMID: 19522266,,,,"Humans; Female; Retrospective Studies; Emergencies; Pregnancy; Japan; Cesarean Section; 00; *Government Agencies; *International Agencies; *Societies, Medical; Disseminated Intravascular Coagulation/*diagnosis/etiology; Platelet Count; Reference Standards; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MPFEPGYL,journalArticle,2009,"Tediosi, Fabrizio; Maire, Nicolas; Penny, Melissa; Studer, Alain; Smith, Thomas A.",Simulation of the cost-effectiveness of malaria vaccines.,Malaria journal,,1475-2875 1475-2875,10.1186/1475-2875-8-127,,"BACKGROUND: A wide range of possible malaria vaccines is being considered and there is a need to identify which vaccines should be prioritized for clinical development. An important element of the information needed for this prioritization is a prediction of the cost-effectiveness of potential vaccines in the transmission settings in which they are likely to be deployed. This analysis needs to consider a range of delivery modalities to ensure that clinical development plans can be aligned with the most appropriate deployment strategies. METHODS: The simulations are based on a previously published individual-based stochastic model for the natural history and epidemiology of Plasmodium falciparum malaria. Three different vaccine types: pre-erythrocytic vaccines (PEV), blood stage vaccines (BSV), mosquito-stage transmission-blocking vaccines (MSTBV), and combinations of these, are considered each delivered via a range of delivery modalities (Expanded Programme of Immunization - EPI-, EPI with booster, and mass vaccination combined with EPI). The cost-effectiveness ratios presented are calculated for four health outcomes, for assumed vaccine prices of US$ 2 or US$ 10 per dose, projected over a 10-year period. RESULTS: The simulations suggest that PEV will be more cost-effective in low transmission settings, while BSV at higher transmission settings. Combinations of BSV and PEV are more efficient than PEV, especially in moderate to high transmission settings, while compared to BSV they are more cost-effective in moderate to low transmission settings. Combinations of MSTBV and PEV or PEV and BSV improve the effectiveness and the cost-effectiveness compared to PEV and BSV alone only when applied with EPI and mass vaccinations. Adding booster doses to the EPI is unlikely to be a cost-effective alternative to delivering vaccines via the EPI for any vaccine, while mass vaccination improves effectiveness, especially in low transmission settings, and is often a more efficient alternative to the EPI. However, the costs of increasing the coverage of mass vaccination over 50% often exceed the benefits. CONCLUSION: The simulations indicate malaria vaccines might be efficient malaria control interventions, and that both transmission setting and vaccine delivery modality are important to their cost-effectiveness. Alternative vaccine delivery modalities to the EPI may be more efficient than the EPI. Mass vaccination is predicted to provide substantial health benefits at low additional costs, although achieving high coverage rates can lead to substantial incremental costs.",08/06/2009,26/11/2018 12:52,14/04/2020 08:35,,127,,,8,,Malar J,,,,,,,,eng,,,,,,,PMID: 19505328 PMCID: PMC2701956,,,,"Humans; Cost-Benefit Analysis; Computer Simulation; Animals; 00; Malaria Vaccines/*economics/*immunology; Malaria, Falciparum/immunology/*prevention & control/transmission; Plasmodium falciparum/immunology; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QGKDCBKS,journalArticle,2009,"Czoski-Murray, Carolyn; Carlton, Jill; Brazier, John; Young, Tracey; Papo, Natalie L.; Kang, Hyong Kwon",Valuing condition-specific health states using simulation contact lenses.,Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research,,1524-4733 1098-3015,10.1111/j.1524-4733.2009.00527.x,,"OBJECTIVE: This article reports on a study that used contact lenses to simulate the effects of a visual impairment caused by age-related macular degeneration (ARMD). The primary objective was to examine the feasibility of using this method of simulation. A secondary objective was to compare the results from this experiment with those obtained from ARMD patients (n = 209) using generic preference-based measures (Health Utilities Index 3 (HUI3) and EUROQOL 5 Dimensions (EQ-5D) and patient time trade-off (TTO). METHODS: Utility values were elicited from healthy participants (n = 108) for three ARMD states simulated using contact lenses. RESULTS: A significant relationship was found between visual acuity and TTO values elicited from our sample population (n = 108). It was stronger than that found for HUI3, EQ-5D, and own TTO values from patients (n = 209). Our sample values informed by the experience of simulation were found to be significantly different from values from patient TTO and generic preference-based measures obtained from patients for the same level of visual impairment. Sociodemographic characteristics did not significantly affect results, although baseline TTO utility values were positively associated with TTO values for simulated states. Nevertheless, the patient population was significantly older than the sample population. CONCLUSIONS: ARMD has a major impact on our sample values TTO health state values. Differences across four visual health severity groups appear larger than those found for a generic preference-based measure and patient TTO values. For conditions that are difficult to describe and imagine, simulation methods may offer an additional tool when combined with usual methods of description for obtaining better informed general population preferences.",2009-08,26/11/2018 12:52,14/04/2020 08:34,,793-799,,5,12,,Value Health,,,,,,,,eng,,,,,,,PMID: 19490557,,,,Humans; Socioeconomic Factors; Adult; Female; Male; Middle Aged; Young Adult; Aged; Severity of Illness Index; Cost of Illness; Visual Acuity; Interviews as Topic; Quality of Life/*psychology; 00; Activities of Daily Living/psychology; Contact Lenses/*psychology; Macular Degeneration/economics/*psychology; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 53W62FGZ,journalArticle,2009,"Meilik, Ahuva; Afek, Arnon; Rotstein, Zeev","[A clinical, health, economic and satisfaction simulation model, CHESS: a tool for healthcare organization management].",Harefuah,,0017-7768 0017-7768,,,"The management of medical organizations is based on a profound understanding of the essence of the organization, its vision and missions, as well as the methods the organization utilizes to gather and analyze information. In order to maintain a maximal function level in an ever-changing environment, all organization components must function in tandem. In a previous article the authors presented medical organizations as macro systems composed of micro systems, and discussed the challenges these organization face today. Basing optimal system management on micro medical systems allows the organizations to make maximum use of the advantages that professionalism encompasses, in a flexible micro-system environment. In this article, the authors attempt to present an interactive solution for performing assessments and management in the medical arena--the CHESS model. This solution was developed at the Sheba Medical Center. The CHESS Simulator (Clinical Health Economic and Satisfaction Simulator) was formulated to function as a clinical organizational intelligence system, whose function was to supply quantitative, analyzed data regarding activity on the clinical production floor. The system is unique in that it has a differential view of the complex medical procedures which are highly variable, and also has the capability to locate elements that are based in a common similarity. Data gathering will be based on an online system computerized medical file (EMR), which is a priority for a functioning system. This solution allows medical organization (macro-system] managers and the departments (micro system) directors to make informed decisions that will ensure that the organization's goals are achieved. This is defined as evolving from a reactive management pattern to a proactive management pattern that is mandatory in the competitive atmosphere of the 21st Century.",2009-03,26/11/2018 12:52,14/04/2020 08:34,,"189-192, 209",,3,148,,Harefuah,,,,,,,,heb,,,,,,,PMID: 19485280,,,,"Humans; *Computer Simulation; Models, Organizational; 1; *Patient Satisfaction; *Job Satisfaction; Delivery of Health Care/*economics/organization & administration; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, R3F36TIV,journalArticle,2010,"Kasuya, Masashi; Meguro, Kenichi",Health economic effect of donepezil treatment for CDR 0.5 converters to Alzheimer's disease as shown by the Markov model.,Archives of gerontology and geriatrics,,1872-6976 0167-4943,10.1016/j.archger.2009.04.014,,"The previous health economic simulation of donepezil based on the Markov model revealed the treatment for mild to moderate stage of Alzheimer disease (AD) to be cost-effective. Our aim was to examine the economic effect of donepezil treatment for mild cognitive impairment, from which about 15% convert to dementia per year. We constructed a new Markov model using three simulations. Namely, Simulation A hypothesized that mild AD patients, i.e., Clinical Dementia Rating (CDR) 1, received donepezil as in the previous study. Simulation B hypothesized that all CDR 0.5 subjects received donepezil, and Simulation C considered that only the CDR 0.5 converters to dementia received donepezil. We calculated the models as follows: Simulation B, supposes that the annual transition probabilities were reduced even from 15% to 10% by donepezil, however, the drug had a negative economic effect. By contrast, in Simulation C, the annual transition probability was reduced from only 15% to 12% by donepezil, there was a positive economic effect. Since it is necessary to reduce the annual transition probability from 15% to 12% in order to manifest a concomitant economic benefit, we consider that early detection of CDR 0.5 converters in the community is important for health policy planning.",2010-06,26/11/2018 12:52,14/04/2020 08:34,,295-299,,3,50,,Arch Gerontol Geriatr,,,,,,,,eng,Copyright (c) 2009 Elsevier Ireland Ltd. All rights reserved.,,,,,,PMID: 19481822,,,,Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Health Care Costs; Aged; Markov Chains; Japan; *Drug Costs; 00; Indans/*economics/therapeutic use; Piperidines/*economics/therapeutic use; Alzheimer Disease/*prevention & control; Cognition Disorders/*drug therapy; Prescription Fees; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QW69XQ32,journalArticle,2009,"Fuller, Jeffrey D.; Kelly, Brian; Law, Susan; Pollard, Georgia; Fragar, Lyn",Service network analysis for agricultural mental health.,BMC health services research,,1472-6963 1472-6963,10.1186/1472-6963-9-87,,"BACKGROUND: Farmers represent a subgroup of rural and remote communities at higher risk of suicide attributed to insecure economic futures, self-reliant cultures and poor access to health services. Early intervention models are required that tap into existing farming networks. This study describes service networks in rural shires that relate to the mental health needs of farming families. This serves as a baseline to inform service network improvements. METHODS: A network survey of mental health related links between agricultural support, health and other human services in four drought declared shires in comparable districts in rural New South Wales, Australia. Mental health links covered information exchange, referral recommendations and program development. RESULTS: 87 agencies from 111 (78%) completed a survey. 79% indicated that two thirds of their clients needed assistance for mental health related problems. The highest mean number of interagency links concerned information exchange and the frequency of these links between sectors was monthly to three monthly. The effectiveness of agricultural support and health sector links were rated as less effective by the agricultural support sector than by the health sector (p < .05). The most highly linked across all areas of activity were Rural Financial Counsellors, the Department of Primary Industry Drought Support Workers and Community Health Centres. Hence for a mental health service network targeting farming families these are three key agencies across the spectrum of case work to program development. The study limitations in describing service networks relate to the accuracy of network bounding, self report bias and missing data from non participants. CONCLUSION: Aligning with agricultural agencies is important to build effective mental health service pathways to address the needs of farming populations. Work is required to ensure that these agricultural support agencies have operational and effective links to primary mental health care services. Network analysis provides a baseline to inform this work. With interventions such as local mental health training and joint service planning to promote network development we would expect to see over time an increase in the mean number of links, the frequency in which these links are used and the rated effectiveness of these links.",29/05/2009,26/11/2018 12:52,14/04/2020 08:34,,87,,,9,,BMC Health Serv Res,,,,,,,,eng,,,,,,,PMID: 19480667 PMCID: PMC2700096,,,,Humans; Health Services Accessibility; Program Evaluation; Surveys and Questionnaires; Health Services Research; Risk Factors; Health Services Needs and Demand; Rural Population; New South Wales; 00; Referral and Consultation; *Agriculture; Rural Health Services/*organization & administration; Community Mental Health Services/*organization & administration; Droughts; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BA8EYLTZ,journalArticle,2009,"Sorensen, Sonja V.; Frick, Kevin D.; Wade, Alexander; Simko, Robert; Burge, Russel",Model-based simulation to explore the cost-effectiveness of following practice guidelines for triglyceride and low-density lipoprotein cholesterol control among patients with diabetes mellitus and mixed dyslipidemia.,Clinical therapeutics,,0149-2918 0149-2918,10.1016/j.clinthera.2009.04.015,,"BACKGROUND: The National Cholesterol Education Program Adult Treatment Panel III guidelines recommend maintaining lipid levels within particular targets to reduce the risk of coronary heart disease (CHD) events. OBJECTIVE: The objective of this simulation study was to evaluate the cost-effectiveness of following guideline-recommended care compared with current practice or usual care for patients with diabetes mellitus (DM) and mixed dyslipidemia (ie, high low-density lipoprotein cholesterol [LDL-C] and triglyceride [TG] levels). METHODS: A simulation model using a US health care payer perspective was designed to predict changes in lipid levels (LDL-C, TG, high-density lipoprotein cholesterol, and total cholesterol) and long-term CHD risk. Data about patients with DM and uncontrolled TG and/or LDL-C were taken from an electronic medical records database to develop the description of current care (eg, statin, fibrate, or no medication) and cholesterol levels. Patients with uncontrolled lipid levels who were not following guideline recommendations were assumed to be receiving combination treatment (ie, coadministration of statin and fibrate) or monotherapy for the uncontrolled lipids under guideline care. Results from a previous study were used to project incremental benefits of combination treatment compared with monotherapy. CHD events were predicted based on risk equations. A 20-year model of direct costs and quality-adjusted life-years (QALYs) was created. RESULTS: Among patients switched to guideline therapy, the model predicted 72% achieved 2 lipid targets and 44% achieved 3 lipid targets in 1 year. Over 20 years, in a modeled sample of 1000 patients, 176 myocardial infarction and angina events would be avoided by following guideline care. Total present value of costs for drug treatment and medical care for CHD events would be $33,626 per patient for guideline treatment versus $25,264 per patient for current care. The discounted QALY gain would be 0.18 per patient for an incremental cost per QALY of $50,315. CONCLUSIONS: The results of this model simulation suggest that for patients with DM and mixed dyslipidemia, following treatment guidelines rather than current practice (including combination therapy rather than monotherapy) would result in more patients achieving lipid targets, fewer CHD events, and more QALYs gained at a reasonable cost (less than $109,000) per QALY.",2009-04,26/11/2018 12:52,14/04/2020 08:35,,862-879,,4,31,,Clin Ther,,,,,,,,eng,,,,,,,PMID: 19446159,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Adult; Female; Male; Middle Aged; Risk Factors; Aged; Aged, 80 and over; United States/epidemiology; Computer Simulation; Models, Statistical; Time Factors; Drug Therapy, Combination; Databases, Factual; Practice Guidelines as Topic/*standards; 00; Cholesterol, LDL/blood/drug effects; Coronary Disease/etiology/prevention & control; Diabetes Mellitus/*blood; Dyslipidemias/complications/*drug therapy/economics; Hypolipidemic Agents/economics/*therapeutic use; Triglycerides/blood; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JTEVCRYA,journalArticle,2009,"Bodger, K.; Kikuchi, T.; Hughes, D.",Cost-effectiveness of biological therapy for Crohn's disease: Markov cohort analyses incorporating United Kingdom patient-level cost data.,Alimentary pharmacology & therapeutics,,1365-2036 0269-2813,10.1111/j.1365-2036.2009.04033.x,,"BACKGROUND: Anti-TNF-alpha agents for Crohn's disease (CD) have good clinical efficacy but high acquisition cost compared to rival drugs. AIM: To assess the cost-effectiveness of infliximab and adalimumab for Crohn's disease from the perspective of the UK NHS, incorporating recent trial and observational data. METHODS: Lifetime Markov analyses constructed to simulate quality-adjusted life-years (QALYs) and costs. CD was represented by four health-states representing: Full response, partial response, nonresponse, surgery and death. The course of CD under standard care was based on the Olmsted county cohort. Systematic review identified ACCENT I (infliximab) and CHARM (adalimumab) as sources for efficacy data. We modelled an intention-to-treat strategy for biologics including surgical rates based on observational data, cost estimates from our UK dataset and utilities from an algorithm converting CDAI to EQ-5D utilities. RESULTS: The incremental cost-effectiveness ratios (ICERs) compared to standard care for 1-year of treatment with infliximab or adalimumab were 19,050 pounds and 7190 pounds per QALY gained, respectively. Lifetime therapy was dominated by standard care. Analyses over shorter time horizons, matched to treatment duration, resulted in unfavourable ICERs. CONCLUSION: The model suggests acceptable ICERs for biological agents when considering a lifetime horizon with periods of up to 4 years continuous therapy. As with all economic evaluations, the results may not be generalizable beyond the perspective of analysis.",2009-08,26/11/2018 12:52,14/04/2020 08:34,,265-274,,3,30,,Aliment Pharmacol Ther,,,,,,,,eng,,,,,,,PMID: 19438428,,,,"Humans; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; United Kingdom; Models, Economic; Adalimumab; Infliximab; 00; National Health Programs/*economics; Cost-Benefit Analysis/*economics; Anti-Inflammatory Agents/*therapeutic use; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal/*economics/therapeutic use; Crohn Disease/drug therapy/*economics; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BWKXVF8P,journalArticle,2009,"Cowie, Martin R.; Marshall, Deborah; Drummond, Michael; Ferko, Nicole; Maschio, Michael; Ekman, Matthias; de Roy, Luc; Heidbuchel, Hein; Verboven, Yves; Braunschweig, Frieder; Linde, Cecilia; Boriani, Giuseppe",Lifetime cost-effectiveness of prophylactic implantation of a cardioverter defibrillator in patients with reduced left ventricular systolic function: results of Markov modelling in a European population.,"Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology",,1532-2092 1099-5129,10.1093/europace/eup068,,"AIMS: Current European guidelines recommend prophylactic implantation of cardioverter defibrillators (ICDs) in patients with a reduced left ventricular ejection fraction (LVEF) who are not in NYHA class IV and have reasonable life expectancy. Cost and benefit implications of this recommendation have not been reported from a European perspective. METHODS AND RESULTS: Markov modelling estimated lifetime costs and effects [life years (LY) and quality-adjusted LY (QALY) gained] of prophylactic ICD implantation vs. conventional treatment, among patients with a reduced LVEF. Efficacy was estimated from a meta-analysis of mortality rates in the six primary prevention trials with inclusion criteria matching ACC/AHA/ESC Class I or IIa recommendations. Direct medical costs were estimated using Belgian national references. Costs and effects were discounted at 3 and 1.5% per annum, respectively. Probabilistic sensitivity and scenario analyses estimated the uncertainty around the incremental cost-effectiveness ratio. An ICD implantation increased the lifetime direct costs by euro 46,413. Estimated mean LY/QALY gained were 1.88/1.57, respectively. Probabilistic analysis estimated mean lifetime cost per QALY gained as euro 31,717 (95% CI: euro 19,760-euro 61,316). Cost-effectiveness was influenced most by ICD efficacy, time to replacement, utility, and patient age at implantation. CONCLUSION: In a European healthcare setting, prophylactic ICD implantation may be cost-effective if current guidelines for patients with a reduced LVEF are followed.",2009-06,26/11/2018 12:52,14/04/2020 08:34,,716-726,,6,11,,Europace,,,,,,,,eng,,,,,,,PMID: 19359333,,,,"Humans; Cost-Benefit Analysis; Treatment Outcome; Female; Male; Middle Aged; Risk Factors; *Models, Economic; Markov Chains; Risk Assessment; Cost of Illness; Europe/epidemiology; Survival Rate; Life Expectancy; Survival Analysis; 00; Death, Sudden, Cardiac/*epidemiology/*prevention & control; Defibrillators, Implantable/*economics; Models, Cardiovascular; Ventricular Dysfunction, Left/*economics/mortality/*prevention & control; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YDHXPCJ6,journalArticle,2009,"Zhang, Hua; Huang, Guo-he; Zeng, Guang-ming","Health risks from arsenic-contaminated soil in Flin Flon-Creighton, Canada: integrating geostatistical simulation and dose-response model.","Environmental pollution (Barking, Essex : 1987)",,1873-6424 0269-7491,10.1016/j.envpol.2009.03.014,,"Elevated concentrations of arsenic were detected in surface soils adjacent to a smelting complex in northern Canada. We evaluated the cancer risks caused by exposure to arsenic in two communities through combining geostatistical simulation with demographic data and dose-response models in a framework. Distribution of arsenic was first estimated using geostatistical circulant-embedding simulation method. We then evaluated the exposures from inadvertent ingestion, inhalation and dermal contact. Risks of skin cancer and three internal cancers were estimated at both grid scale and census-unit scale using parametric dose-response models. Results indicated that local residents could face non-negligible cancer risks (skin cancer and liver cancer mainly). Uncertainties of risk estimates were discussed from the aspects of arsenic concentrations, exposed population and dose-response model. Reducing uncertainties would require additional soil sampling, epidemic records as well as complementary studies on land use, demographic variation, outdoor activities and bioavailability of arsenic.",2009-09,26/11/2018 12:52,14/04/2020 08:35,,2413-2420,,08-Sep,157,,Environ Pollut,,,,,,,,eng,,,,,,,PMID: 19359076,,,,"Humans; Female; Male; *Models, Statistical; Dose-Response Relationship, Drug; Risk Assessment/methods; Demography; 00; Environmental Exposure/*statistics & numerical data; Arsenic/analysis/*toxicity; Environmental Pollution/statistics & numerical data; Liver Neoplasms/epidemiology; Lung Neoplasms/epidemiology; Manitoba/epidemiology; Saskatchewan/epidemiology; Skin Neoplasms/epidemiology; Soil Pollutants/analysis/*toxicity; Statistics as Topic; Urinary Bladder Neoplasms/epidemiology; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4SCL5H7Y,journalArticle,2009,"Naaldenberg, Jenneken; Vaandrager, Lenneke; Koelen, Maria; Wagemakers, Anne-Marie; Saan, Hans; de Hoog, Kees",Elaborating on systems thinking in health promotion practice.,Global health promotion,,1757-9759 1757-9759,10.1177/1757975908100749,,"Health and well-being are the result of a series of complex processes in which an individual interacts with other people and the environment. A systematic approach ensures incorporation of individual, ecological, social and political factors. However, interactions between these factors can be overlooked within a systematical approach. A systemic approach can provide additional information by incorporating interactions and communication. The opportunities of a systems thinking perspective for health promotion were investigated for this paper. Although others have also made attempts to explore systems thinking in the field of health promotion, the implications of systems thinking in practice need attention. Other fields such as agricultural extension studies, organizational studies and development studies provide useful experiences with the use of a systems thinking perspective in practice. Building on experiences from these fields, we give a theoretical background in which processes of social learning and innovation play an important role. From this background, we derive an overview of important concepts for the practical application of a systems thinking perspective. These concepts are the structure of the system, meanings attached to actions, and power relations between actors. To make these concepts more explicit and reduce the theoretical character of systems thinking, we use an illustration to elaborate on these concepts in practice. For this purpose, we describe a health promotion partnership in The Netherlands using the concepts structure, meaning and power relations. We show how a systems perspective increases insight in the functioning of a partnership and how this can facilitate processes of social learning and innovation. This article concludes by identifying future opportunities and challenges in adopting systems thinking for health promotion practice. A systems perspective towards health promotion can help projects reaching a more integral and sustainable approach in which the complex nature of health promotion processes is supported. Practical applications of systems thinking are necessary to adapt this perspective.",2009-03,26/11/2018 12:52,14/04/2020 08:35,,39-47,,1,16,,Glob Health Promot,,,,,,,,eng,,,,,,,PMID: 19276332,,,,Humans; Community Health Services/*organization & administration; *Systems Theory; Health Behavior; Interinstitutional Relations; Community-Institutional Relations; Power (Psychology); 1; Health Promotion/methods/*organization & administration; Social Environment; Internal-External Control; Political Systems; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3A7PPVNM,journalArticle,2009,"Gekas, Jean; Gagne, Genevieve; Bujold, Emmanuel; Douillard, Daniel; Forest, Jean-Claude; Reinharz, Daniel; Rousseau, Francois",Comparison of different strategies in prenatal screening for Down's syndrome: cost effectiveness analysis of computer simulation.,BMJ (Clinical research ed.),,1756-1833 0959-8138,10.1136/bmj.b138,,"OBJECTIVES: To assess and compare the cost effectiveness of three different strategies for prenatal screening for Down's syndrome (integrated test, sequential screening, and contingent screenings) and to determine the most useful cut-off values for risk. DESIGN: Computer simulations to study integrated, sequential, and contingent screening strategies with various cut-offs leading to 19 potential screening algorithms. DATA SOURCES: The computer simulation was populated with data from the Serum Urine and Ultrasound Screening Study (SURUSS), real unit costs for healthcare interventions, and a population of 110 948 pregnancies from the province of Quebec for the year 2001. MAIN OUTCOME MEASURES: Cost effectiveness ratios, incremental cost effectiveness ratios, and screening options' outcomes. RESULTS: The contingent screening strategy dominated all other screening options: it had the best cost effectiveness ratio ($C26,833 per case of Down's syndrome) with fewer procedure related euploid miscarriages and unnecessary terminations (respectively, 6 and 16 per 100,000 pregnancies). It also outperformed serum screening at the second trimester. In terms of the incremental cost effectiveness ratio, contingent screening was still dominant: compared with screening based on maternal age alone, the savings were $C30,963 per additional birth with Down's syndrome averted. Contingent screening was the only screening strategy that offered early reassurance to the majority of women (77.81%) in first trimester and minimised costs by limiting retesting during the second trimester (21.05%). For the contingent and sequential screening strategies, the choice of cut-off value for risk in the first trimester test significantly affected the cost effectiveness ratios (respectively, from $C26,833 to $C37,260 and from $C35,215 to $C45,314 per case of Down's syndrome), the number of procedure related euploid miscarriages (from 6 to 46 and from 6 to 45 per 100,000 pregnancies), and the number of unnecessary terminations (from 16 to 26 and from 16 to 25 per 100,000 pregnancies). CONCLUSIONS: Contingent screening, with a first trimester cut-off value for high risk of 1 in 9, is the preferred option for prenatal screening of women for pregnancies affected by Down's syndrome.",13/02/2009,26/11/2018 12:52,14/04/2020 08:34,,b138,,,338,,BMJ,,,,,,,,eng,,,,,,,PMID: 19218323 PMCID: PMC2645848,,,,"Humans; Cost-Benefit Analysis; Adult; Female; Middle Aged; Young Adult; Decision Support Techniques; *Computer Simulation; Pregnancy; 00; Statistics as Topic; Abortion, Induced/utilization; Age Distribution; Down Syndrome/*diagnosis/economics; Health Services Misuse/economics/statistics & numerical data; Maternal Age; Pregnancy Outcome; Pregnancy Trimester, First; Pregnancy Trimester, Second; Prenatal Diagnosis/*economics/methods; Quebec; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, T29HXPWS,journalArticle,2009,"Tumeh, John W.; Shenoy, Pareen J.; Moore, Susan G.; Kauh, John; Flowers, Christopher",A Markov model assessing the effectiveness and cost-effectiveness of FOLFOX compared with FOLFIRI for the initial treatment of metastatic colorectal cancer.,American journal of clinical oncology,,1537-453X 0277-3732,10.1097/COC.0b013e31817c6a4d,,"OBJECTIVE: To analyze the efficacy and cost-effectiveness of FOLFOX compared with FOLFIRI for patients with metastatic colorectal cancer. METHOD: We developed a Markov decision model using a hypothetical cohort of patients with metastatic colorectal cancer to compare beginning chemotherapy with FOLFOX or FOLFIRI. Probabilities of toxicities, including neutropenia, diarrhea, and neuropathy, were based on published literature for FOLFOX and FOLFIRI. Costs for physician and hospital services unadjusted for geographic location were estimated using Centers for Medicare and Medicaid services reimbursement data. Drug costs were estimated using Medicare B reimbursement and the Federal Supply Schedule. Health outcomes were measured in quality-adjusted life years (QALYs). Univariate and probabilistic sensitivity analyses were performed to address uncertainty in the model parameters. RESULTS: The FOLFOX strategy provided 1.003 QALYs at a cost of $29,865, whereas FOLFIRI provided 0.921 QALYs at a cost of $24,551. The incremental cost-effectiveness ratio for FOLFOX treatment was $65,170/QALY. In 10,000 probabilistic Monte Carlo simulations, FOLFOX was cost-effective in 48.59% of trials using a $50,000/QALY threshold. The most influential variables in univariate sensitivity analysis were the expected years of survival associated with each chemotherapy regimen. CONCLUSIONS: FOLFOX and FOLFIRI are similar in terms of costs and benefits. The slight QALY benefits associated with FOLFOX are within the range of $100,000/QALY, an accepted threshold in oncology.",2009-02,26/11/2018 12:52,14/04/2020 08:35,,49-55,,1,32,,Am J Clin Oncol,,,,,,,,eng,,,,,,,PMID: 19194125,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Treatment Outcome; Cohort Studies; Quality of Life; *Markov Chains; Sensitivity and Specificity; Disease-Free Survival; Neoplasm Staging; *Models, Econometric; Antineoplastic Combined Chemotherapy Protocols/economics/*therapeutic use; Camptothecin/analogs & derivatives/economics/therapeutic use; Colorectal Neoplasms/*drug therapy/*economics/secondary; Fluorouracil/economics/therapeutic use; Leucovorin/economics/therapeutic use; Organoplatinum Compounds/economics/therapeutic use; 00; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 744343YL,journalArticle,2009,"Parks, Amanda L.; Walker, Brett; Pettey, Warren; Benuzillo, Jose; Gesteland, Per; Grant, Juliana; Koopman, James; Drews, Frank; Samore, Matthew",Interactive agent based modeling of public health decision-making.,AMIA ... Annual Symposium proceedings. AMIA Symposium,,1942-597X 1559-4076,,,"Agent-based models have yielded important insights regarding the transmission dynamics of communicable diseases. To better understand how these models can be used to study decision making of public health officials, we developed a computer program that linked an agent-based model of pertussis with an agent-based model of public health management. The program, which we call the Public Health Interactive Model & simulation (PHIMs) encompassed the reporting of cases to public health, case investigation, and public health response. The user directly interacted with the model in the role of the public health decision-maker. In this paper we describe the design of our model, and present the results of a pilot study to assess its usability and potential for future development. Affinity for specific tools was demonstrated. Participants ranked the program high in usability and considered it useful for training. Our ultimate goal is to achieve better public health decisions and outcomes through use of public health decision support tools.",14/11/2009,26/11/2018 12:52,14/04/2020 08:34,,504-508,,,2009,,AMIA Annu Symp Proc,,,,,,,,eng,,,,,,,PMID: 20351907 PMCID: PMC2815457,,,,Humans; *Public Health; *Computer Simulation; Pilot Projects; *Decision Support Techniques; Epidemiologic Methods; Disease Outbreaks; Software; *Decision Making; Professional Competence; Public Health Administration; 1; Disease Notification; Whooping Cough/transmission; Agent Based; 210,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, P4I8CLBB,journalArticle,2009,"Wan, Michael J.; Krahn, Murray; Ungar, Wendy J.; Caku, Edona; Sung, Lillian; Medina, L. Santiago; Doria, Andrea S.",Acute appendicitis in young children: cost-effectiveness of US versus CT in diagnosis--a Markov decision analytic model.,Radiology,,1527-1315 0033-8419,10.1148/radiol.2502080100,,"PURPOSE: To compare the cost-effectiveness of different imaging strategies in the diagnosis of pediatric appendicitis by using a decision analytic model. MATERIALS AND METHODS: Approval for this retrospective study based on literature review was not required by the institutional Research Ethics Board. A Markov decision model was constructed by using costs, utilities, and probabilities from the literature. The risk of radiation-induced cancer was modeled by using the Biological Effects of Ionizing Radiation VII report, which is based primarily on data from atomic bomb survivors. The three imaging strategies were ultrasonography (US), computed tomography (CT), and US followed by CT if the initial US study was negative. The model simulated the short-term and long-term outcomes of the patients, calculating the average quality-adjusted life span and health care costs. RESULTS: For a single abdominal CT study in a 5-year-old child, the lifetime risk of radiation-induced cancer would be 26.1 per 100,000 in female and 20.4 per 100,000 in male patients. In the base-case analysis, US followed by CT was the most costly and most effective strategy, CT was the second-most costly and second-most effective strategy, and US was the least costly and least effective strategy. The incremental cost-effectiveness ratios (ICERs) of CT to US and of US followed by CT to US were both well below the societal willingness-to-pay threshold of $50,000 (in U.S. dollars). The ICER of US followed by CT to CT was less than $10,000 in both male and female patients. CONCLUSION: In a Markov-based decision model of pediatric appendicitis, the most cost-effective method of imaging pediatric appendicitis was to start with a US study and follow each negative US study with a CT examination.",2009-02,26/11/2018 12:52,14/04/2020 08:35,,378-386,,2,250,,Radiology,,,,,,,,eng,,,,,,,PMID: 19098225,,,,"Humans; Cost-Benefit Analysis; Female; Male; Retrospective Studies; *Markov Chains; Incidence; Child, Preschool; Risk; Prevalence; Sensitivity and Specificity; Radiation Dosage; 00; *Decision Trees; Appendicitis/*diagnostic imaging/epidemiology; Intestinal Perforation/epidemiology; Neoplasms, Radiation-Induced/epidemiology; SEER Program; Tomography, X-Ray Computed/adverse effects/*economics; Ultrasonography/*economics; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3AZMCBX2,journalArticle,2008,"Freimuth, Vicki S.; Hilyard, Karen M.; Barge, J. Kevin; Sokler, Lynn A.","Action, not talk: a simulation of risk communication during the first hours of a pandemic.",Health promotion practice,,1524-8399 1524-8399,10.1177/1524839908322111,,"This article describes the design, implementation, and evaluation of a simulation of risk communication in the first hours of a pandemic. The simulation design was based on Crisis and Emergency Risk Communication principles espoused by the Centers for Disease Control and Prevention, as well as the collective experience of the authors. Over 4 hours, 17 local health district risk communicators in Georgia responded to a scenario in which every community in the state had teenagers infected with avian flu after returning from an international conference. The evaluation revealed that local risk communicators had much greater difficulty following risk communication principles under the time pressures of a realistic and stressful event than they did in a tabletop exercise. Strengths and weaknesses of the performance of the local risk communicators are identified in addition to lessons learned about the design and implementation of a risk communication simulation.",2008-10,26/11/2018 12:52,14/04/2020 08:34,,35S-44S,,4 Suppl,9,,Health Promot Pract,,,,,,,,eng,,,,,,,PMID: 18936258,,,,"Humans; *Patient Simulation; United States/epidemiology; Risk; Disease Outbreaks/*prevention & control; Influenza, Human/epidemiology/*prevention & control; Communicable Disease Control/*methods; 00; Georgia; *Information Dissemination; Regional Health Planning; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3TBN6ZEL,journalArticle,2009,"Acheson, Ashley; Robinson, Jennifer L.; Glahn, David C.; Lovallo, William R.; Fox, Peter T.",Differential activation of the anterior cingulate cortex and caudate nucleus during a gambling simulation in persons with a family history of alcoholism: studies from the Oklahoma Family Health Patterns Project.,Drug and alcohol dependence,,1879-0046 0376-8716,10.1016/j.drugalcdep.2008.08.019,,"Individuals with a family history of alcoholism (FH+) are at enhanced risk of developing an alcohol or other substance use disorder relative to those without this history (FH-). Recent studies comparing FH+ and FH- individuals have revealed differences in cognition, emotion processing, sociability, and decision-making. These differences suggest possible altered brain functioning in FH+ individuals that may play a crucial role in vulnerability to substance use disorders. In the present study, 15 FH+ and 19 FH- individuals performed the Iowa Gambling Task (IGT), a simulated card game requiring integration of payoff-to-penalty ratios, while undergoing functional magnetic resonance imaging. All participants performed the task more conservatively as the session progressed, and the FH groups achieved similar payoffs by the end of the game. Imaging revealed a distributed network of brain regions that was engaged when subjects performed this task, including the right inferior frontal and postcentral gyri, left parahippocampal gyrus, insula and precuneous cortices, left inferior and superior parietal lobules, left lentiform nucleus and bilateral culmen, claustrum, lingual gyri and cerebellar tonsils. Despite a lack of behavioral differences between groups, the FH+ participants showed significantly more activation in the left dorsal anterior cingulate cortex and left caudate nucleus. These findings correspond to models of risk in FH+ persons that postulate biases in brain decision-making systems as underlying elevated risk for alcoholism.",01/02/2009,26/11/2018 12:52,14/04/2020 08:34,,17-23,,01-Feb,100,,Drug Alcohol Depend,,,,,,,,eng,,,,,,,PMID: 19026496 PMCID: PMC2637537,,,,Humans; Female; Male; Young Adult; Cohort Studies; Health Behavior; 00; Oklahoma; *Family Health; Alcoholism/genetics/*metabolism/*psychology; Brain Mapping/methods; Caudate Nucleus/*metabolism; Cerebral Cortex/metabolism; Gambling/*psychology; Gyrus Cinguli/*metabolism; Photic Stimulation/methods; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Q9WJPIQG,journalArticle,2008,"Ara, Roberta; Pandor, Abdullah; Tumur, Indra; Paisley, Suzy; Duenas, Alejandra; Williams, Robert; Wilkinson, Anna; Durrington, Paul; Chilcott, Jim",Estimating the health benefits and costs associated with ezetimibe coadministered with statin therapy compared with higher dose statin monotherapy in patients with established cardiovascular disease: results of a Markov model for UK costs using data registries.,Clinical therapeutics,,0149-2918 0149-2918,10.1016/j.clinthera.2008.08.002,,"BACKGROUND: Ezetimibe has been reported to improve lipid control in patients with established cardiovascular disease (CVD). OBJECTIVE: The aim of this study was to estimate the potential long-term impact on health status of prescribing ezetimibe in combination with statin therapy in patients with established CVD and evaluate its cost-effectiveness in a health economic model. METHODS: A Markov model was used to compare ezetimibe and statin combination therapy with statin monotherapy. A published relationship linking changes in low-density lipoprotein cholesterol and cardiovascular events was used to estimate the cardiovascular events avoided through lipid-lowering therapies. The model was populated using results of extensive literature searches and a meta-analysis of clinical evidence. An adjustment was applied to model second-line lipid-lowering benefits. Conservative assumptions were used to extend the patient pathway beyond the clinical evidence. The analysis took the perspective of the UK Department of Health; therefore, only direct costs were included. Costs were calculated as year-2006 British pounds. RESULTS: For a cohort of 1,000 hypothetical male patients aged 55 years, ezetimibe coadministered with current statin therapy was estimated to prevent a mean of 43 nonfatal myocardial infarctions, 7 nonfatal strokes, and 26 cardiovascular deaths over a lifetime, compared with doubling the current statin dose. The events avoided would provide a mean of 134 additional quality-adjusted life-years (QALYs). With a mean incremental cost of pound 3,693,000, the lifetime discounted cost per QALY gained would be pound 27,475 (95% CI, pound 27,331- pound 27,620) and would rise to pound 32,000 for men aged 75 years. CONCLUSIONS: The results suggest that, in some instances, ezetimibe coadministration may be cost-effective compared with statin monotherapy, but there are several limitations with this model. The economic effects of ezetimibe must be revisited when long-term effectiveness and safety data become available.",2008-08,26/11/2018 12:52,14/04/2020 08:34,,1508-1523,,8,30,,Clin Ther,,,,,,,,eng,,,,,,,PMID: 18803993,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Female; Male; Middle Aged; Risk Factors; Aged; Markov Chains; Quality of Life; United Kingdom; Dose-Response Relationship, Drug; Age Factors; Drug Therapy, Combination; Sex Factors; 00; Anticholesteremic Agents/*economics/therapeutic use; Azetidines/*economics/therapeutic use; Cardiovascular Diseases/etiology/*prevention & control; Ezetimibe; Hydroxymethylglutaryl-CoA Reductase Inhibitors/*economics/therapeutic use; Hypercholesterolemia/complications/drug therapy; Lipoproteins, LDL/blood; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9T7XW7BC,journalArticle,2008,"Brown, J. F.",Applications of simulation technology in psychiatric mental health nursing education.,Journal of psychiatric and mental health nursing,,1365-2850 1351-0126,10.1111/j.1365-2850.2008.001281.x,,"The purpose of this paper is to review the use of simulation in education across the health professionals, to describe the development and implementation of innovative simulation techniques for an undergraduate psychiatric mental-health nursing course, and to identify lessons learned and future directions for successful simulation experiences in psychiatric nursing.",2008-10,26/11/2018 12:52,14/04/2020 08:34,,638-644,,8,15,,J Psychiatr Ment Health Nurs,,,,,,,,eng,,,,,,,PMID: 18803737,,,,"Humans; Forecasting; Clinical Competence; Nursing Education Research; *Patient Simulation; *Computer Simulation; Communication; Models, Educational; Problem-Based Learning; Nurse-Patient Relations; *Manikins; Educational Technology; Diffusion of Innovation; Role Playing; Videotape Recording; 00; Patient Education as Topic; Computer-Assisted Instruction; Education, Nursing, Baccalaureate/*methods/trends; Nurse's Role/psychology; Psychiatric Nursing/*education/methods; Virginia; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, F36F7KKJ,journalArticle,2008,"Yao, Guiqing; Freemantle, Nick; Flather, Marcus; Tharmanathan, Puvan; Coats, Andrew; Poole-Wilson, Philip A.",Long-term cost-effectiveness analysis of nebivolol compared with standard care in elderly patients with heart failure: an individual patient-based simulation model.,PharmacoEconomics,,1170-7690 1170-7690,10.2165/00019053-200826100-00007,,"BACKGROUND AND OBJECTIVE: The SENIORS trial demonstrated that nebivolol is effective in the treatment of heart failure in elderly patients (e.g. > or = 70 years). This analysis evaluates the cost effectiveness of nebivolol compared with standard treatment. METHODS: An individual patient-simulation model based on a Markov modelling framework was developed to compare costs and outcomes for nebivolol and standard care in patients with heart failure starting treatment at the age of 70 years. Health states were defined by New York Heart Association (NYHA) class and death. At a given NYHA class and a given cycle, patients could die, be hospitalized for cardiovascular disease or remain stable. Risks for these events were derived from individual patient data from the SENIORS trial. The risk of each event in a given cycle was based on the subject's baseline characteristics and time in the current health state. The economic analysis was conducted from the UK NHS perspective with a lifetime horizon. The costs (euro; year 2006 values) considered were drug costs for nebivolol and other cardiac drugs, costs of GP visits, outpatient specialist visits and cardiovascular-related hospitalizations. Univariate and probabilistic sensitivity analysis was conducted. RESULTS: In the baseline analysis, the total cost per patient was euro6740 and euro9288, and QALYs were 5.194 and 5.843 for patients aged 70 years at the start of treatment for the standard treatment and nebivolol groups, respectively. The probabilistic sensitivity analysis provided an incremental cost-effectiveness ratio of euro3926 (95% CI 3731, 4159) per QALY. CONCLUSIONS: This analysis indicates that nebivolol appears to be a cost-effective treatment for elderly patients with heart failure compared with standard care.",2008,26/11/2018 12:52,14/04/2020 08:35,,879-889,,10,26,,Pharmacoeconomics,,,,,,,,eng,,,,,,,PMID: 18793034,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Female; Male; *Models, Economic; Aged; Markov Chains; Health Care Costs/statistics & numerical data; Aged, 80 and over; Computer Simulation; United Kingdom; 00; Heart Failure/*drug therapy/economics; Adrenergic beta-Antagonists/economics/*therapeutic use; Benzopyrans/economics/*therapeutic use; Ethanolamines/economics/*therapeutic use; Nebivolol; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TZWSS2H3,journalArticle,2008,"Borg, Sixten; Glenngard, Anna H.; Osterborg, Anders; Persson, Ulf",The cost-effectiveness of treatment with erythropoietin compared to red blood cell transfusions for patients with chemotherapy induced anaemia: a Markov model.,"Acta oncologica (Stockholm, Sweden)",,1651-226X 0284-186X,10.1080/02841860701744498,,"BACKGROUND: Anaemia is a common complication of chemotherapy. As anaemia can lead to e.g. fatigue, depression, social isolation and chest pain it diminishes physical capacity and quality of life. It is generally accepted that symptomatic anaemia should be corrected. Treatment options include red blood cell transfusion (RBCT), erythropoietin (EPO) administration or a combination of both. OBJECTIVE: The objective of this study was to carry out a cost-effectiveness analysis of treatment with EPO (epoetin alfa), compared to treatment with RBCT for patients with chemotherapy-induced anaemia in Sweden from a health care perspective. METHOD: A model was developed for estimating incremental costs and QALY gains associated with EPO treatment compared to treatment with RBCTs, based on a model commissioned by the UK National Institute for Health and Clinical Excellence and adjusted to reflect Swedish treatment practice. Data regarding patient characteristics, response rates, and RBCT was derived from a Swedish observational study of EPO treatment in cancer patients with chemotherapy related anaemia. Swedish guidelines and unit costs were used throughout the study. A systematic review of EPO for treatment of anaemia associated with cancer was used to estimate QALY gains associated with changes in Hb-concentrations in our model. RESULTS: The model's results validate well to real world data from three major hospitals in Sweden. The cost per QALY gained from administration of EPO was estimated at EUR 24,700 in the base case analysis. Practicing an EPO treatment target Hb-level of 12 g/dl yields a cost per QALY about 40% lower than practicing a Hb-target level of 13 g/dl, which is in agreement with updated recommendations of using a 12 g/dl target. CONCLUSION: The estimated cost per QALY falls well within the range acceptable in Sweden when practicing a Hb-target level of 12 g/dl. The incremental cost of elevating Hb-levels above 13 g/dl is very high in relation to the incremental QALY gain achieved.",2008,26/11/2018 12:52,14/04/2020 08:34,,1009-1017,,6,47,,Acta Oncol,,,,,,,,eng,,,,,,,PMID: 18770060,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Adult; Female; Male; Middle Aged; Aged; Markov Chains; Quality of Life; Severity of Illness Index; Sweden; 00; Anemia, Hypochromic/blood/*chemically induced/*economics; Antineoplastic Agents/administration & dosage/*adverse effects; Epoetin Alfa; Erythrocyte Transfusion/adverse effects/*economics; Erythropoietin/*economics/*therapeutic use; Hematinics/*economics/*therapeutic use; Hemoglobins/metabolism; Recombinant Proteins; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Q4JDKZ96,journalArticle,2008,"Baker, Cynthia; Pulling, Cheryl; McGraw, Robert; Dagnone, Jeffrey Damon; Hopkins-Rosseel, Diana; Medves, Jennifer",Simulation in interprofessional education for patient-centred collaborative care.,Journal of advanced nursing,,1365-2648 0309-2402,10.1111/j.1365-2648.2008.04798.x,,"AIM: This paper is a report of preliminary evaluations of an interprofessional education through simulation project by focusing on learner and teacher reactions to the pilot modules. BACKGROUND: Approaches to interprofessional education vary widely. Studies indicate, however, that active, experiential learning facilitate it. Patient simulators require learners to incorporate knowing, being and doing in action. A theoretically based competency framework was developed to guide interprofessional education using simulation. The framework includes a typology of shared, complementary and profession-specific competencies. Each competency type is associated with an intraprofessional, multiprofessional, or interprofessional teaching modality and with the professional composition of learner groups. METHOD: The project is guided by an action research approach in which ongoing evaluation generates knowledge to modify and further develop it. Preliminary evaluations of the first pilot module, cardiac resuscitation rounds, among 101 nursing students, 42 medical students and 70 junior medical residents were conducted in 2005-2007 using a questionnaire with rating scales and open-ended questions. Another 20 medical students, 7 junior residents and 45 nursing students completed a questionnaire based on the Interdisciplinary Education Perception scale. FINDINGS: Simulation-based learning provided students with interprofessional activities they saw as relevant for their future as practitioners. They embraced both the interprofessional and simulation components enthusiastically. Attitudinal scores and responses were consistently positive among both medical and nursing students. CONCLUSION: Interprofessional education through simulation offers a promising approach to preparing future healthcare professionals for the collaborative models of healthcare delivery being developed internationally.",2008-11,26/11/2018 12:52,14/04/2020 08:34,,372-379,,4,64,,J Adv Nurs,,,,,,,,eng,,,,,,,PMID: 18764851,,,,Humans; Program Evaluation; Reproducibility of Results; Interdisciplinary Communication; *Interprofessional Relations; *Cooperative Behavior; Attitude of Health Personnel; 00; *Patient-Centered Care/organization & administration/standards; Advanced Cardiac Life Support/*education; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KK6XWK7X,journalArticle,2008,"Leischow, Scott J.; Best, Allan; Trochim, William M.; Clark, Pamela I.; Gallagher, Richard S.; Marcus, Stephen E.; Matthews, Eva",Systems thinking to improve the public's health.,American journal of preventive medicine,,0749-3797 0749-3797,10.1016/j.amepre.2008.05.014,,"Improving population health requires understanding and changing societal structures and functions, but countervailing forces sometimes undermine those changes, thus reflecting the adaptive complexity inherent in public health systems. The purpose of this paper is to propose systems thinking as a conceptual rubric for the practice of team science in public health, and transdisciplinary, translational research as a catalyst for promoting the functional efficiency of science. The paper lays a foundation for the conceptual understanding of systems thinking and transdisciplinary research, and will provide illustrative examples within and beyond public health. A set of recommendations for a systems-centric approach to translational science will be presented.",2008-08,26/11/2018 12:52,14/04/2020 08:34,,S196-203,,2 Suppl,35,,Am J Prev Med,,,,,,,,eng,,,,,,,PMID: 18619400 PMCID: PMC3940421,,,,Humans; *Public Health; *Cooperative Behavior; *Interdisciplinary Communication; *Systems Theory; Public Health Administration; 1; *Group Processes; Science/organization & administration; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9GMN6CJA,journalArticle,2008,"Cai, Liming; Schenker, Nathaniel; Lubitz, James; Diehr, Paula; Arnold, Alice; Fried, Linda P.",Evaluation of a method for fitting a semi-Markov process model in the presence of left-censored spells using the Cardiovascular Health Study.,Statistics in medicine,,0277-6715 0277-6715,10.1002/sim.3382,,We used a longitudinal data set covering 13 years from the Cardiovascular Health Study to evaluate the properties of a recently developed approach to deal with left censoring that fits a semi-Markov process (SMP) model by using an analog to the stochastic EM algorithm--the SMP-EM approach. It appears that the SMP-EM approach gives estimates of duration-dependent probabilities of health changes similar to those obtained by using SMP models that have the advantage of actual duration data. SMP-EM estimates of duration-dependent transition probabilities also appear more accurate and less variable than multi-state life table estimates.,20/11/2008,26/11/2018 12:52,14/04/2020 08:34,,5509-5524,,26,27,,Stat Med,,,,,,,,eng,,,,,,,PMID: 18712777 PMCID: PMC2878178,,,,"Humans; Female; Male; Aged; *Models, Statistical; *Markov Chains; Aged, 80 and over; Time Factors; Disease Progression; Data Interpretation, Statistical; Longitudinal Studies; Stochastic Processes; 1; Activities of Daily Living; *Cardiovascular Diseases; Cardiovascular System; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3XM3R5ZE,journalArticle,2007,"Clancy, Thomas R.; Delaney, Connie White; Segre, Alberto; Carley, Kathleen; Kuziak, Andrew; Yu, Hwanjo",Predicting the impact of an electronic health record on practice patterns using computational modeling and simulation.,AMIA ... Annual Symposium proceedings. AMIA Symposium,,1942-597X 1559-4076,,,"The overall purpose of this research study is to discover and apply new knowledge regarding methods to predict the impact of an electronic health record (EHR) on clinical practice guidelines in complex systems such as hospitals. Specifically, the aims of this study are: 1) to build, simulate and validate the accuracy of a computational model representing the current practice patterns in a sample of patients diagnosed with heart failure (HF) and treated in a community hospital; and 2) using computational modeling and simulation, develop a method to predict the effects of best practice guidelines on practice patterns after implementation of an EHR.",11/10/2007,26/11/2018 12:52,14/04/2020 08:34,,145-149,,,,,AMIA Annu Symp Proc,,,,,,,,eng,,,,,,,PMID: 18693815 PMCID: PMC2813672,,,,"Humans; *Computer Simulation; Organizational Case Studies; discrete event simulation; Organizational Innovation; Cost Savings; 1; *Practice Guidelines as Topic; *Medical Records Systems, Computerized; *Guideline Adherence/economics; *Practice Patterns, Physicians'/economics/standards/statistics & numerical data; Clinical Laboratory Techniques/utilization; Electrocardiography/utilization; Heart Failure/diagnosis/*therapy; Hospitals, Community/economics/manpower; Medical Staff, Hospital/economics/statistics & numerical data; Nursing Staff, Hospital/economics/statistics & numerical data; Workload/statistics & numerical data; X",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3C9GBR5U,journalArticle,2008,"Boerjan, Martine; Boone, Frederik; Anthierens, Sibyl; van Weel-Baumgarten, Evelyn; Deveugele, Myriam",The impact of repeated simulation on health and healthcare perceptions of simulated patients.,Patient education and counseling,,0738-3991 0738-3991,10.1016/j.pec.2008.05.028,,"OBJECTIVE: To explore the effect of simulating medical conditions on simulated patients (SPs). Main points of interest are influence on: perception of personal health and perception of their relation with the health care provider (HCP), personal well being. METHODS: Semi-structured interviews were undertaken with eight experienced, well-selected SPs involved in communication training at the medical faculty of Ghent University. Content of the data were analysed qualitatively. RESULTS: SPs believe that their medical knowledge improved, which changes their health-seeking behaviour. Simulating made SPs realize that being a doctor is difficult, making them more critical towards their own GP. SPs enjoy their work; they feel happy and content afterwards. Negative effects are stress, anxiety, exhaustion, dissatisfaction and sleeping problems. DISCUSSION: The perceived 'increased knowledge' leads to a different way of dealing with symptoms. It is positive that SPs are more critical towards their GP, this leads to a more equal relationship. The effects of stress and anxiety probably contribute positively to the performance. Dissatisfaction, anxiety and sleeping problems could be work-related and consequently occur in practicing other occupations. PRACTICE IMPLICATIONS: Proper selection, preparation and guidance could minimize the problems encountered during simulation.",2008-10,26/11/2018 12:52,14/04/2020 08:34,,22-27,,1,73,,Patient Educ Couns,,,,,,,,eng,,,,,,,PMID: 18650054,,,,"Humans; Netherlands; Adult; Female; Male; Middle Aged; *Patient Simulation; *Physician-Patient Relations; Adaptation, Psychological; 00; *Education, Medical; *Occupational Health; *Attitude to Health; Stress, Psychological; Emotions; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HRCWTVBC,journalArticle,2008,"Valente, Thomas W.; Coronges, Kathryn A.; Stevens, Gregory D.; Cousineau, Michael R.",Collaboration and competition in a children's health initiative coalition: a network analysis.,Evaluation and program planning,,1873-7870 0149-7189,10.1016/j.evalprogplan.2008.06.002,,"Activating communities to achieve public health change and initiate policy reform usually requires collective action from many entities. This case study analyzes inter-organizational networks among members of a coalition created to expand health insurance coverage to uninsured children in a large metropolitan area. Six networks were measured: collaboration, competition, formal agreements, receive funding from, send funding to, and greater communication. The response rate was 65.8% (50 of the 76 active members). Positive network questions such as ""who do you collaborate with"" elicited many network choices whereas negative ones such as ""who do you compete with"" elicited few. The collaboration network had a core-periphery structure and analysis showed that a large network can be reduced to a small set of core organizations one-sixth the size of the whole. Centrality (out- and in-degree) was associated with perceived organizational function and perceived barriers to success. For example, organizations that received many choices as collaboration partners were more likely to perceive the coalition functioned well than those who received few choices. The study suggests that perceptions of organizational performance are associated with position in the network, central members are more likely to perceive the organization performs well than those on the periphery.",2008-11,26/11/2018 12:52,14/04/2020 08:35,,392-402,,4,31,,Eval Program Plann,,,,,,,,eng,,,,,,,PMID: 18639933,,,,"Humans; United States; Child; Cooperative Behavior; Child Health Services/*organization & administration; Interinstitutional Relations; Community Networks/*organization & administration; 00; State Health Plans; *Insurance, Health; Health Care Coalitions/*organization & administration; Health Care Reform/economics/methods/*organization & administration; Medically Uninsured; Urban Health; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7TS7R68J,journalArticle,2008,"Fronstin, Paul; Salisbury, Dallas; VanDerhei, Jack",Savings needed to fund health insurance and health care expenses in retirement: findings from a simulation model.,EBRI issue brief,,0887-137X 0887-137X,,,"MODELING RETIREE HEALTH COSTS: This Issue Brief examines the uncertainty of health care expenses in retirement by using a Monte Carlo simulation model to estimate the amount of savings needed to cover health insurance premiums and out-of-pocket health care expenses. This type of simulation is able to account for the uncertainty related to individual mortality and rates of return, and computes the present value of the savings needed to cover health insurance premiums and out-of-pocket expenses in retirement. These observations were used to determine asset targets for having adequate savings to cover retiree health costs 50, 75, and 90 percent of the time. NOT ENOUGH SAVINGS: Many individuals will need more money than the amounts reported in this Issue Brief because this analysis does not factor in the savings needed to cover long-term care expenses, nor does it take into account the fact that many individuals retire prior to becoming eligible for Medicare. However, some workers will need to save less than what is reported if they keep working in retirement and receive health benefits as active workers. WHO HAS RETIREE HEALTH BENEFITS BEYOND MEDICARE?: About 12 percent of private-sector employers report offering any Medicare supplemental health insurance. This increases to about 40 percent among large employers. Overall, nearly 22 percent of retirees age 65 and older had retiree health benefits in 2005 to supplement Medicare coverage. As recently as 2006, 53 percent of retirees age 65 and older were covered by Medicare Part D, 24 percent had outpatient prescription drug coverage through an employment-based plan. Only 10 percent had no prescription drug coverage. INDIVIDUALLY PURCHASED MEDICARE SUPPLEMENTS, 2008: Among those who purchase Medigap and Medicare Part D prescription drug coverage at age 65 in 2008, men would need between $79,000 and $159,000 with median prescription drug expenses (50th percentile and 90th percentiles, respectively), and between $156,000 and $331,000 with prescription spending that is at the 90th percentile. Women would need between $108,000 and $184,000 with median prescription drug expenses (50th and 90th percentiles, respectively), and between $217,000 and $390,000 with prescription spending that is at the 90th percentile. The savings needed for couples would range from $194,000 at the 50th percentile to $635,000 at the 90th percentile.",2008-05,26/11/2018 12:52,14/04/2020 08:34,,"1-2, 4-27",,317,,,EBRI Issue Brief,,,,,,,,eng,,,,,,,PMID: 18630312,,,,"Humans; United States; Female; Male; Middle Aged; Aged; Health Care Costs/statistics & numerical data; 00; Private Sector; State Health Plans; *Health Expenditures; *Medicare/economics/statistics & numerical data/trends; Health Benefit Plans, Employee; Insurance, Health/*economics/trends; Insurance, Medigap/economics/statistics & numerical data; Pensions/statistics & numerical data; Retirement/*economics/statistics & numerical data; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HDVRPNP9,journalArticle,2008,"Stamper, David H.; Jones, Robert S.; Thompson, Jennifer C.",Simulation in health care provider education at Brooke Army Medical Center.,Military medicine,,0026-4075 0026-4075,,,"The teaching and assessment of clinical skills are critical components of health care provider education, and clinical skill proficiency is essential for safe and successful health care delivery. Medical simulation is being increasingly recognized in health care education as an extremely valuable mechanism for training and assessing clinical skills. As in other high-stakes professions, the use of simulation can enhance the proficiency and efficiency of training while maximizing safety and minimizing risk. Located within Brooke Army Medical Center, the Trauma Simulation Training Center is a multifaceted, full-service, medical simulation facility. In an effort to improve and to expand the role of simulation, we collected data on utilization of the facility and the level of overall satisfaction among our users. Results showed that the primary users were graduate medical education physicians-in-training. In addition, survey results demonstrated that users favored simulation-based learning because of the realism of simulated scenarios. The Trauma Simulation Training Center embraces the simulation-based medical education philosophy by actively inviting training program participation, and we realize that more research is needed to determine the effectiveness of this teaching and assessment modality.",2008-06,26/11/2018 12:52,14/04/2020 08:35,,583-587,,6,173,,Mil Med,,,,,,,,eng,,,,,,,PMID: 18595423,,,,"Humans; Delivery of Health Care; *Patient Simulation; Emergency Medicine/*education; *Computer Simulation; *Clinical Competence; Texas; Health Personnel/*education; Teaching/*methods; 00; Competency-Based Education/*methods; *Hospitals, Military; Education, Medical, Graduate/*methods; Military Medicine/*education; Traumatology/*education; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 485DCRRS,journalArticle,2008,"Gold, Marsha; Doreian, Patrick; Taylor, Erin Fries",Understanding a collaborative effort to reduce racial and ethnic disparities in health care: contributions from social network analysis.,Social science & medicine (1982),,0277-9536 0277-9536,10.1016/j.socscimed.2008.05.020,,"Quality improvement collaboratives have become a common strategy for improving health care. This paper uses social network analysis to study the relationships among organizations participating in a large scale public-private collaboration among major health plans to reduce racial and ethnic disparities in health care in the United States. Pre-existing ties, the collaborative process, participants' perceived contributions, and the overall organizational standing of participants were examined. Findings suggest that sponsors and support organizations, along with a few of the health plans, form the core of this network and act as the ""glue"" that holds the collaboration together. Most health plans (and one or two support organizations) are in the periphery. While health plans do not interact much with one another, their interactions with the core organizations provided a way of helping achieve health plans' disparities goals. The findings illustrate the role sponsors can play in encouraging organizations to voluntarily work together to achieve social ends while also highlighting the challenges.",2008-09,26/11/2018 12:52,14/04/2020 08:34,,1018-1027,,6,67,,Soc Sci Med,,,,,,,,eng,,,,,,,PMID: 18579272,,,,Humans; United States; Healthcare Disparities; Health Services Accessibility/*organization & administration; *Cooperative Behavior; 00; Patient Care Management/*organization & administration; Health Care Reform/organization & administration; *Ethnic Groups; *Managed Care Programs; Social Justice; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, F7IB4K3J,journalArticle,2008,"Manning, B. R. M.; McCann, J.; Benton, S.; Bougourd, J.",Active ageing: independence through technology assisted health optimisation.,Studies in health technology and informatics,,0926-9630 0926-9630,,,"The potential doubling in the percentage of the elderly within the populations of Europe and beyond over the next decades has focused informatics research on the development Assistive Technologies and Smart Homes. However its concentration on creating a supportive home environment also has the potential for makings its users over dependent on its facilities and as a result trapped within it. This paper outlines an approach that extends the smart homes concept out into the wider community to create a smart environment that not only maintains contact with all their home-based services, but also expands these to include other facilities needed to assist them whilst on the move. This involves the convergence of physiological monitoring, communications and computing with leading-edge textile technologies, which uses a multi-layered, multi-functional clothing system as a mobile and extended variant of a smart home IP hub. In addition to variable functionality capabilities of the clothing layers in terms of thermal, shock-absorbent and other characteristics, wireless IP connectivity is provided between layers with external links typically being WiFi enabled. Health optimisation is provided by on-going lifestyle guidance/action feedback based on auto-diagnostic analysis.",2008,26/11/2018 12:52,14/04/2020 08:34,,257-262,,,137,,Stud Health Technol Inform,,,,,,,,eng,,,,,,,PMID: 18560086,,,,"Humans; Aged; Communication; Europe; Life Style; 00; Telemedicine/*trends; Population Dynamics; *Environment Design; Clothing; Computer Systems/*trends; Health Services for the Aged/*trends; Monitoring, Physiologic/instrumentation; Self-Help Devices/*trends; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4G6KWWVJ,journalArticle,2008,"Xie, Feng; Luo, Nan; Lee, Hin-Peng",Cost effectiveness analysis of population-based serology screening and (13)C-Urea breath test for Helicobacter pylori to prevent gastric cancer: a markov model.,World journal of gastroenterology,,1007-9327 1007-9327,,,"AIM: To compare the costs and effectiveness of no screening and no eradication therapy, the population-based Helicobacter pylori (H pylori) serology screening with eradication therapy and (13)C-Urea breath test (UBT) with eradication therapy. METHODS: A Markov model simulation was carried out in all 237900 Chinese males with age between 35 and 44 from the perspective of the public healthcare provider in Singapore. The main outcome measures were the costs, number of gastric cancer cases prevented, life years saved, and quality-adjusted life years (QALYs) gained from screening age to death. The uncertainty surrounding the cost-effectiveness ratio was addressed by one-way sensitivity analyses. RESULTS: Compared to no screening, the incremental cost-effectiveness ratio (ICER) was $16166 per life year saved or $13571 per QALY gained for the serology screening, and $38792 per life year saved and $32525 per QALY gained for the UBT. The ICER was $477079 per life year saved or $390337 per QALY gained for the UBT compared to the serology screening. The cost-effectiveness of serology screening over the UBT was robust to most parameters in the model. CONCLUSION: The population-based serology screening for H pylori was more cost-effective than the UBT in prevention of gastric cancer in Singapore Chinese males.",21/05/2008,26/11/2018 12:52,14/04/2020 08:35,,3021-3027,,19,14,,World J Gastroenterol,,,,,,,,eng,,,,,,,PMID: 18494053 PMCID: PMC2712169,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Health Care Costs; Adult; Male; *Markov Chains; Drug Costs; Computer Simulation; Models, Theoretical; Anti-Bacterial Agents/economics/therapeutic use; Mass Screening/*economics/methods; Helicobacter pylori/*isolation & purification; 00; Singapore; *Breath Tests; Carbon Isotopes; Helicobacter Infections/complications/*diagnosis/drug therapy/economics/microbiology; Serologic Tests/*economics; Stomach Neoplasms/economics/microbiology/*prevention & control; Urea/*economics; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FPNFCRLL,journalArticle,2008,"Howard, Paul; Knight, Christopher; Boler, Annabel; Baker, Christine",Cost-utility analysis of varenicline versus existing smoking cessation strategies using the BENESCO Simulation model: application to a population of US adult smokers.,PharmacoEconomics,,1170-7690 1170-7690,10.2165/00019053-200826060-00004,,"BACKGROUND: Of 1 346 700 total deaths each year in the US, an estimated 440 100 are smoking related, making it the leading preventable cause of premature death in the US. Despite the health and economic benefits of smoking cessation being well documented, reimbursement coverage for smoking cessation therapies is generally limited in the US and elsewhere. OBJECTIVES: To evaluate the cost effectiveness of varenicline, an alpha 4 beta 2 nicotinic acetylcholine receptor partial agonist, recently approved to aid smoking cessation. METHODS: A Markov model, the Benefits of Smoking Cessation on Outcomes (BENESCO) model, was developed to simulate the lifetime direct costs and consequences of a hypothetical cohort of US adult smokers who make a one-time attempt to quit smoking. The smoking cessation strategies compared were varenicline, bupropion, nicotine replacement therapy and unaided quitting. The model used the hazard ratios from the Cancer Prevention Study (CPS)-II study for the mortality of smoking-related diseases as a proxy to calculate the relative risks of the incidence and prevalence of these diseases, following previously developed methodology. The costs (year 2005 values) and utilities for the included smoking-related diseases (lung cancer, chronic obstructive lung disease [COPD], coronary heart disease [CHD], stroke and asthma exacerbations), and the efficacies of the smoking cessation strategies, were sourced from the published literature. Costs and benefits were discounted at 3% pa. Probabilistic and univariate sensitivity analyses were conducted. RESULTS: Varenicline was found to dominate all other smoking cessation strategies that were investigated for both the 20-year and lifetime timeframe. Furthermore, if 25% of the current population of US smokers made a one-time attempt to quit using varenicline compared with unaided cessation, almost 144 000 smoking-related deaths and over 261 000 cases of asthma exacerbations, COPD, CHD, stroke and lung cancer could be avoided compared with an unaided smoking cessation strategy. CONCLUSIONS: Varenicline, a recently approved therapy for smoking cessation, is likely to be a cost-effective alternative compared with currently available options.",2008,26/11/2018 12:52,14/04/2020 08:34,,497-511,,6,26,,Pharmacoeconomics,,,,,,,,eng,,,,,,,PMID: 18489200,,,,"Humans; United States; Adult; Female; Male; Middle Aged; Markov Chains; *Models, Statistical; Adolescent; Drug Costs; Costs and Cost Analysis; 1; Varenicline; Benzazepines/*economics/therapeutic use; Bupropion/*economics/therapeutic use; Nicotine/administration & dosage/*economics; Quinoxalines/*economics/therapeutic use; Smoking Cessation/*economics/methods/statistics & numerical data; Smoking/adverse effects; Markov; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BX86GDT3,journalArticle,2008,"Nevin, Remington L.; Shuping, Eric E.; Frick, Kevin D.; Gaydos, Joel C.; Gaydos, Charlotte A.",Cost and effectiveness of Chlamydia screening among male military recruits: Markov modeling of complications averted through notification of prior female partners.,Sexually transmitted diseases,,0148-5717 0148-5717,10.1097/OLQ.0b013e31816d1f55,,"BACKGROUND: Despite rising rates of female screening, a high economic burden remains associated with Chlamydia infection from high rates of undetected asymptomatic disease and its associated sequelae of pelvic inflammatory disease (PID) and chronic pelvic pain (CP). Males comprise the majority of US military recruits and represent an ideal population in which to achieve identification and interruption of sexually transmitted infection among infected partners through mass tandem screening. METHODS: We developed a static decision tree incorporating a calibrated Markov model to predict the differences in healthcare payer direct healthcare costs, cases of PID and CP averted among female partners of male recruits through implementation of either selective (aged 24 and younger) or universal recruit screening policies incorporating partner notification. RESULTS: A policy of selective male screening added $10.30 in direct costs per recruit, whereas universal male screening added an additional $1.60. A policy of selective male screening yielded an incremental cost-effectiveness ratio of $3.7K per case of PID averted, and $7.3K per case of CP averted, whereas universal screening yielded an incremental cost-effectiveness ratio of $8.2K per additional case of PID and $16.4K per additional case of CP averted beyond selective screening. Neither policy was dominant, and results were qualitatively robust to single-variable and probabilistic sensitivity analysis. CONCLUSIONS: In consonance with other studies of mass tandem screening, we found both selective and universal male recruit screening cost-effective as compared with other interventions. Our results argue in favor of universal screening of male recruits for Chlamydia infection, linked to partner notification.",2008-08,26/11/2018 12:52,14/04/2020 08:35,,705-713,,8,35,,Sex Transm Dis,,,,,,,,eng,,,,,,,PMID: 18461015,,,,Humans; United States; Cost-Benefit Analysis; Female; Male; Markov Chains; Decision Trees; Cost of Illness; Mass Screening/*economics; 00; Chlamydia Infections/*diagnosis/*economics/prevention & control; Contact Tracing; Direct Service Costs; Military Personnel; Pelvic Inflammatory Disease/*economics/prevention & control; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, NJD7GU29,journalArticle,2009,"van den Hout, Ardo; Matthews, Fiona E.",A piecewise-constant Markov model and the effects of study design on the estimation of life expectancies in health and ill health.,Statistical methods in medical research,,0962-2802 0962-2802,10.1177/0962280208089090,,"Multi-state models are frequently applied to describe transitions over time between three states: healthy, not healthy and death. The three-state model can be used to estimate life expectancies in health and ill health. In this article, continuous-time Markov models are specified for the transitions between the three states. Transition intensities are regressed on age as a time-dependent covariate. The covariate is handled in a piecewise-constant fashion where the time interval between two consecutive observations is divided into subintervals of fixed and equal lengths. Study design choices such as sample size, length of follow-up, and time intervals between observations are investigated in a simulation study. The effects on parameter estimation are discussed as well as the effects on the estimation of life expectancies. In addition, data taken from the UK Cognitive Functioning and Ageing Study are analysed.",2009-04,26/11/2018 12:52,14/04/2020 08:35,,145-162,,2,18,,Stat Methods Med Res,,,,,,,,eng,,,,,,,PMID: 18445698,,,,"Humans; Female; Male; Aged; *Markov Chains; Models, Statistical; United Kingdom; Cognition; Longitudinal Studies; Biometry; *Life Expectancy; 1; Aging/psychology; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9XDXDG4E,journalArticle,2008,"Chen, J.; Alemao, E.; Yin, D.; Cook, J.",Development of a diabetes treatment simulation model: with application to assessing alternative treatment intensification strategies on survival and diabetes-related complications.,"Diabetes, obesity & metabolism",,1463-1326 1462-8902,10.1111/j.1463-1326.2008.00885.x,,"AIMS: The objective of this analysis is to project the long-term impacts on life expectancy and occurrence over 5, 10, and 40 years of microvascular and macrovascular complications of diabetes when using different haemoglobin A1c (HbA1c) thresholds for intensifying treatment of type 2 diabetes. METHODS: A flexible, discrete-event simulation model has been developed to evaluate alternative treatment strategies based on the United Kingdom Prospective Diabetes Study Outcomes Model. In the present analysis, the model is used to investigate the impact of alternative HbA1c thresholds for treatment intensification ranging from 7.0 to 9.0%. For each intensification strategy, the model is run using 80 simulated patients for each of 1224 patient profiles from the Real-Life Effectiveness and Care Patterns of Diabetes Management study (for a total of 97,920 simulated patients) to project the number of patients who will experience diabetes-related complications over time. RESULTS: The use of lower HbA1c thresholds for intensifying treatment is associated with improved long-term outcomes. When the HbA1c threshold for intensifying therapy from oral treatment to basal insulin (T1) is 7.0% and the threshold for intensifying basal insulin to multiple-dose insulin (T2) is 7.0%, simulated patients spend 54% of their time with HbA1c >7.0%, but 95% of their time with HbA1c >7.0% if T1 and T2 are set to 9.0%. More aggressive or proactive treatment postures are projected to reduce clinical events, including diabetes-related deaths and diabetes-related complications, particularly myocardial infarctions (MIs). When T1 and T2 are set to 7.0%, there are 592 fewer diabetes-related deaths in the first 5 years of the simulation and 3740 fewer deaths over 40 years compared with the results when T1 and T2 are set to 9.0%. These decreases in deaths were also associated with a 0.35 year gain in projected life expectancy. Compared with an aggressive strategy with both T1 and T2 being 7%, 644 more patients are projected to experience at least one episode of MI in the first 5 years if treatment intensification is delayed until HbA1c reaches 9.0%. This number increases over time, reaching 2906 additional patients experiencing at least one MI over a 40-year time period. CONCLUSIONS: We report results from a discrete-event simulation model to explore the impact of alternative treatment strategies for patients with type 2 diabetes. Strategies that intensify therapy (in response to rising HbA1c levels) at lower HbA1c thresholds (e.g. 7.0%) are associated with enhanced projected long-term health outcomes.",2008-06,26/11/2018 12:52,14/04/2020 08:34,,33-42,,,10 Suppl 1,,Diabetes Obes Metab,,,,,,,,eng,,,,,,,PMID: 18435672,,,,"Humans; Prognosis; *Models, Biological; *Computer Simulation; United Kingdom; 1; Amputation; Hypoglycemic Agents/*administration & dosage; Diabetes Mellitus, Type 2/complications/*drug therapy; Blindness/etiology; Cardiovascular Diseases/complications; Diabetes Complications/*prevention & control; Glycated Hemoglobin A/drug effects; Insulin/administration & dosage; Metformin/administration & dosage; Renal Insufficiency/etiology; Sulfonylurea Compounds/administration & dosage; Thiazolidinediones/administration & dosage; Discrete event; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GCBUYTAJ,journalArticle,2008,"Kirbach, Stephanie; Simpson, Kit; Nietert, Paul J.; Mintzer, Jacobo",A markov model of the cost effectiveness of olanzapine treatment for agitation and psychosis in Alzheimer's disease.,Clinical drug investigation,,1173-2563 1173-2563,10.2165/00044011-200828050-00003,,"BACKGROUND AND OBJECTIVE: Antipsychotics have long been used to treat agitation and psychosis related to Alzheimer's disease, but in a limited fashion because of troubling adverse effects. The new atypical antipsychotics are thought to be at least as effective as first-generation drugs and to cause fewer adverse effects. These drugs, however, are currently not US FDA-approved for use among elderly demented subjects due to a slight increase in the risk of death and serious cardiovascular events within this population. However, their favourable adverse effect profile has led many physicians to prescribe these drugs as first-line therapy for behaviourally disturbed patients with Alzheimer's disease. Clinical trials to evaluate the use of atypical antipsychotics have produced varying results, and clarity has not yet been achieved. Thus, a quantitative summary of the risks and benefits may help inform complex decisions that must be made in this area. In this study we set out to compare the expected costs and outcomes for a community-dwelling cohort of patients with Alzheimer's disease with agitation and/or psychosis who are (a) untreated, or (b) treated with olanzapine. METHODS: We constructed a Markov state-transition model using the best published data from several sources for Alzheimer's disease patient progression and treatment. This model allowed us to compare the expected costs and outcomes associated with olanzapine treatment compared with no treatment for a synthetic cohort of US adults aged > or =65 years. The model cycles every 6 months and continues until all patients die from Alzheimer's disease progression or from co-morbid conditions. Outcome estimates included the incremental cost-effectiveness ratio (ICER) and cost per quality-adjusted life-year (QALY) gained. The robustness of the estimates was examined by sensitivity analyses of key parameters, including cost of care, olanzapine effectiveness and Alzheimer's disease progression rates. RESULTS: Results indicated that olanzapine was a cost-effective treatment for agitation and psychosis related to Alzheimer's disease when compared with no treatment (ICER <$US50,000). In addition, sensitivity analyses demonstrated that olanzapine remained cost effective despite multiple variations of several parameters, both alone and concurrently. CONCLUSION: Olanzapine treatment for agitation and psychosis related to Alzheimer's disease is cost effective when compared with no treatment. Further analysis should be performed as atypical antipsychotics become generic, as more information on health utilities in the Alzheimer's disease population becomes available, and to compare atypical antipsychotics with first-generation antipsychotics.",2008,26/11/2018 12:52,14/04/2020 08:34,,291-303,,5,28,,Clin Drug Investig,,,,,,,,eng,,,,,,,PMID: 18407715,,,,Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Treatment Outcome; Aged; Cohort Studies; Markov Chains; Drug Costs; United States/epidemiology; Proportional Hazards Models; Mortality; Alzheimer Disease/*complications/psychology; Antipsychotic Agents/*economics/*therapeutic use; Benzodiazepines/*economics/*therapeutic use; Ethnic Groups; Psychomotor Agitation/*drug therapy/*etiology; Psychotic Disorders/*drug therapy/*etiology; 00; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 96BEF8RL,journalArticle,2008,"Kozmenko, Valeriy; Paige, John; Chauvin, Sheila",Initial implementation of mixed reality simulation targeting teamwork and patient safety.,Studies in health technology and informatics,,0926-9630 0926-9630,,,"Patient safety is one of the most pressing challenges of modern healthcare. Being a multifactorial problem, patient safety requires improvement interventions on multiple levels including individual, team and organization as a whole. Using high-fidelity human patient simulator in real clinical setting allows creating a mixed reality environment for teaching healthcare teams to improve patient safety. A multidisciplinary group of physicians at Louisiana State University Health Sciences Center in New Orleans has developed and implemented the STEPS program (System for Teamwork Effectiveness and Patient Safety) with the use of MMOR (mobile mock operating room) configuration to train general surgical teams within their own operating room environment. Each simulation session was followed by facilitated debriefing and teaching new team communication skills. Team performances were assessed by both direct observation and team's self-assessment where each team member assessed his or her own performance as well as the performance of all other team members (360 degree assessment).",2008,26/11/2018 12:52,14/04/2020 08:34,,216-221,,,132,,Stud Health Technol Inform,,,,,,,,eng,,,,,,,PMID: 18391289,,,,Humans; Female; Male; *Computer Simulation; Interdisciplinary Communication; *Cooperative Behavior; *Safety Management; *User-Computer Interface; 00; Point-of-Care Systems; Operating Rooms; Louisiana; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EJ3AUJ9F,journalArticle,2008,"Minerba, Luigi; Chessa, Alessandro; Coppola, Rosa Cristina; Mula, Gianni; Cappellini, Giancarlo",A complex network analysis of a health organization.,Igiene e sanita pubblica,,0019-1639 0019-1639,,,"The analysis of organizational structures of healthcare organizations such as University teaching hospitals is a fundamental step toward improving health care services and making more efficient use of available resources. In this study, discharge abstract data from the University of Cagliari teaching hospital was analysed by using techniques borrowed from the theory of complex networks. A bipartite network was constructed by linking the physician and diagnosis fields of the discharge abstract data. The unipartite projection network was then constructed by quantifying the number of diagnoses the connected physicians had in common in one year. Community detection algorithms were then used to identify the 'best' community structure (i.e. organizational subdivisions) for the hospital organization. The identified community structure could lead to improved efficiency with respect to existing departmental divisions. Results show how the theory of complex networks can be a very powerful data mining tool with very promising implications for research in the fields of health care organizations and social networks.",2008-01,26/11/2018 12:52,14/04/2020 08:34,,Sep-25,,1,64,,Ig Sanita Pubbl,,,,,,,,eng,,,,,,,PMID: 18379603,,,,"Humans; Algorithms; *Social Support; Italy; *Community Networks; 00; Health Services/*standards; Hospitals, Teaching/*organization & administration; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5BUHZA5I,journalArticle,2008,"Kepler, Kalle; Vladimirov, Anatoli",Optimisation strategies introduced for CR at health care centres in Estonia.,Radiation protection dosimetry,,0144-8420 0144-8420,10.1093/rpd/ncn004,,"In recent years, starting from 2001, conventional film-screen radiography has been rapidly replaced by digital (mostly by computed radiography, CR) techniques in Estonia. New strategies for optimisation and quality assurance for digital radiography have been introduced by the DIMOND III and SENTINEL partners recently. It includes consideration to diagnostic requirements of a given clinical situation, but also objectivation and standardisation of image quality, e.g. using CDRAD test phantom, and constancy testing. The aim of this work is to evaluate the performance of an automatic exposure control (AEC) at different sensitivities when used with the Fujifilm CR system. Image quality, using threshold contrast-detail detectability (TCDD) and signal-to-noise ratio squared related to dose (SNR2/D), was also investigated for different sensitivities and tube potential values for this combination. Based on the image evaluation data, optimum speed modes for the organ programme settings have been proposed.",2008,26/11/2018 12:52,14/04/2020 08:34,,127-131,,01-Mar,129,,Radiat Prot Dosimetry,,,,,,,,eng,,,,,,,PMID: 18252852,,,,"Humans; Radiation Dosage; 00; *Community Health Centers; Estonia; Phantoms, Imaging; Radiographic Image Enhancement/*instrumentation/*methods; Radiographic Image Interpretation, Computer-Assisted/methods; Tomography, X-Ray Computed/*instrumentation/*methods; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, R27JW8EM,journalArticle,2007,"LaMontagne, Anthony D.; Keegel, Tessa; Vallance, Deborah",Protecting and promoting mental health in the workplace: developing a systems approach to job stress.,Health promotion journal of Australia : official journal of Australian Association of Health Promotion Professionals,,1036-1073 1036-1073,,,"ISSUE ADDRESSED: Job stress has been linked to a wide range of adverse effects on mental, physical, and organisational health. Despite the evidence that systems approaches are most effective in reducing the adverse impact of job stress, prevalent practice is dominated by worker- or individual-focused strategies in the absence of commensurate intervention on working conditions. METHODS: A literature review and cross-disciplinary conceptual synthesis were combined in the articulation of a systems approach to job stress. RESULTS: An outline of the job stress process is followed by explanation of how a systems approach addresses the various steps in the stress process. Systems approaches to job stress emphasise primary prevention or focusing on stressors as the upstream determinants of job stress. Additionally, systems approaches integrate primary with worker-directed secondary and illness-directed tertiary intervention, include the meaningful participation of groups targeted by intervention, and are context-sensitive. Systems approach intervention principles are illustrated by concrete examples of intervention strategies and activities. CONCLUSIONS: Further efforts are needed to promote, disseminate, implement, and evaluate systems approaches to job stress and to improve cross-disciplinary co-operation in this effort.",2007-12,26/11/2018 12:52,14/04/2020 08:34,,221-228,,3,18,,Health Promot J Austr,,,,,,,,eng,,,,,,,PMID: 18201165,,,,"Humans; *Health Promotion; 00; *Mental Health; Occupational Health; Organizational Policy; Stress, Psychological/*prevention & control/*therapy; Workplace/organization & administration/*psychology; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KXU34SLQ,journalArticle,2008,"Issenberg, S. Barry; Scalese, Ross J.",Simulation in health care education.,Perspectives in biology and medicine,,0031-5982 0031-5982,10.1353/pbm.2008.0004,,"During the past 15 years there has been widespread adoption of simulation in health care education as a method to train and assess learners. Multiple factors have contributed to this movement, including reduced patient availability, limited faculty teaching time, technological advances in diagnosis and treatment that require a new skills set, greater attention to patient safety with the need to reduce medical errors, and a focus on outcomes-based education. In this discussion, simulation refers broadly to any device or set of conditions that attempts to present the patient authentically. While simulation offers many advantages over traditional methods of teaching, there are several challenges that must be addressed to ensure its effective use. This article presents the range of available simulation technologies, explores the challenges that health care educators face when using this method, provides an example of a successful program that has integrated simulation into the culture of learning at its institution, and discusses an approach to maximizing the effectiveness of simulation as a means to learning and practicing skills in a safe, interactive environment.",2008,26/11/2018 12:52,14/04/2020 08:34,,31-46,,1,51,,Perspect Biol Med,,,,,,,,eng,,,,,,,PMID: 18192764,,,,"Humans; Clinical Competence; *Patient Simulation; Reproducibility of Results; Curriculum; *Computer Simulation; 1; Education, Medical/*methods; Cardiology/education; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9GJBSQ9L,journalArticle,2007,"Harrison, Michael I.; Henriksen, Kerm; Hughes, Ronda G.",Improving the health care work environment: a sociotechnical systems approach.,Joint Commission journal on quality and patient safety,,1553-7250 1553-7250,,,"This issue examines findings on key elements of the hospital environment, identifies risks to safety and quality, and proposes operational and policy solutions.",2007-11,26/11/2018 12:52,14/04/2020 08:34,,"3-6, 1",,11 Suppl,33,,Jt Comm J Qual Patient Saf,,,,,,,,eng,,,,,,,PMID: 18173161,,,,"Humans; Health Services Research; *Environment; *Models, Organizational; *Hospital Administration; Risk Management; 00; Quality of Health Care/*organization & administration; Sociology, Medical; Workplace/*organization & administration; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DPARTFL8,journalArticle,2007,"Anderson, James; Chaturvedi, Alok; Cibulskis, Mike",Simulation tools for developing policies for complex systems: modeling the health and safety of refugee communities.,Health care management science,,1386-9620 1386-9620,,,"The U.S. Committee for Refugees and Immigrants estimated that there were over 33 million refugees and internally displaced persons (IDPs) in the world at the beginning of 2005. IDP/Refugee communities behave in complex ways making it difficult to make policy decisions regarding the provision of humanitarian aid and health and safety. This paper reports the construction of an agent-based model that has been used to study humanitarian assistance policies executed by governments and NGOs that provide for the health and safety of refugee communities. Agent-based modeling (ABM) was chosen because the more widely used alternatives impose unrealistic restrictions and assumptions on the system being modeled and primarily apply to aggregate data. We created intelligent agents representing institutions, organizations, individuals, infrastructure, and governments and analyzed the resulting interactions and emergent behavior using a Central Composite Design of Experiments with five factors. The resulting model allows policy makers and analysts to create scenarios, to make rapid changes in parameters, and provides a test bed for concepts and strategies. Policies can be examined to see how refugee communities might respond to alternative courses of action and how these actions are likely to affect the health and well-being of the community.",2007-12,26/11/2018 12:52,14/04/2020 08:34,,331-339,,4,10,,Health Care Manag Sci,,,,,,,,eng,,,,,,,PMID: 18074966,,,,"Delivery of Health Care/*organization & administration; Humans; United States; Safety Management/*organization & administration; *Models, Organizational; Patient safety; *Decision Support Systems, Management; *Policy Making; 1; *Refugees; Agent Based; 220",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3939UNSR,journalArticle,2007,"Castelli, Christel; Combescure, Christophe; Foucher, Yohann; Daures, Jean-Pierre",Cost-effectiveness analysis in colorectal cancer using a semi-Markov model.,Statistics in medicine,,0277-6715 0277-6715,10.1002/sim.3112,,"Cost and effectiveness are usually modeled according to one studied event or one health state with parametric or non-parametric methods. In this paper, we propose an original method for assessing total costs while incorporating the dynamics of change in the health status of patients. A semi-Markov model in which the distributions of sojourn times are explicitly defined is developed. The hazard function of sojourn times is modeled by Weibull distributions specific to each transition. A vector of covariates is incorporated into the hazard function of each transition. From a regression model for costs, a cumulative cost function is derived. An estimation of the mean cost per patient in each state defined in the semi-Markov model could thus be made, and this enables us to identify the determinants of direct costs. The results of incremental net benefit (INB) are assessed using the bootstrap method. A cost-effectiveness analysis is performed in order to compare two strategies of follow-up in the colorectal cancer study. Two hundred and forty patients were enrolled in this study. Three health states are defined for patients with curative resection of colorectal cancer: alive without relapse, alive with relapse, and dead. The mean survival is 4.35 and 4.12 years, respectively, in the standard and moderate follow-up groups. We show that mean cost differs significantly by follow-up strategy and Dukes stage. Finally, the INB is assessed and this indicates that neither of the strategies compared was more cost-effective than the other.",30/12/2007,26/11/2018 12:52,14/04/2020 08:34,,5557-5571,,30,26,,Stat Med,,,,,,,,eng,"Copyright (c) 2007 John Wiley & Sons, Ltd.",,,,,,PMID: 18058847,,,,"Humans; Female; Male; Middle Aged; Reproducibility of Results; Aged; Follow-Up Studies; Health Care Costs/statistics & numerical data; *Markov Chains; Aged, 80 and over; Feasibility Studies; Disease Progression; Regression Analysis; Health Status; Cost-Benefit Analysis/*methods; Disease-Free Survival; Neoplasm Staging; Recurrence; 00; Probability Theory; Colorectal Neoplasms/*economics/rehabilitation/surgery; Colorectal Surgery/rehabilitation; Personal Health Services/economics/statistics & numerical data; Postoperative Period; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KZBTADMP,journalArticle,2007,"Rwashana, Agnes Semwanga; Williams, Ddembe Wileese",Enhancing immunization coverage through health information systems: a system dynamics approach.,Studies in health technology and informatics,,0926-9630 0926-9630,,,"This paper demonstrates how qualitative System Dynamics methodology can be used to provide a better understanding of health systems thus facilitating better development and design of computer-based health information systems. In an earlier paper by the same authors, system dynamics modeling and field study research methods are used to capture the complex and dynamic nature of the immunization process, to enhance the understanding of the immunization health care problems and to generate insights that may increase the immunization coverage effectiveness. Through qualitative modeling, causal loop diagrams which are used to show the key issues that need to be addressed when developing health information systems are drawn with the aim of improving the immunization services. The paper shows the benefits of using System Dynamics to understand systems with complex interactions thus facilitating the development of information systems that meet the stakeholder requirements.",2007,26/11/2018 12:52,14/04/2020 08:34,,247-256,,,130,,Stud Health Technol Inform,,,,,,,,eng,,,,,,,PMID: 17917198,,,,Humans; World Health Organization; *Computer Simulation; System dynamics; 1; Developing Countries; *Immunization; Information Systems/*organization & administration; 210,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PF9JDEMU,journalArticle,2007,"Orfanidis, Leonidas; Bamidis, Panagiotis D.; Eaglestone, Barry",A simulation-based performance analysis of a National Electronic Health Record System.,Studies in health technology and informatics,,0926-9630 0926-9630,,,"This paper addresses through simulation experiments a number of technical issues which are raised during the development and operation of a National Electronic Health Record System (NEHRS). The simulation experiments represent the NEHRS performance for a variety of technological infrastructures, within the context of a realistic scenario. The scenario includes the estimation of the delays created in queues during the exchange of Electronic Patient Records (EPR) between different health service points. It is essential to clarify the delays derive from LAN and Internet technologies, the EPR encryption/decryption, the HL7 message generation/parsing, and the databases. The results of this study identify how a number of technical aspects influence the NEHRS development and operation.",2007,26/11/2018 12:52,14/04/2020 08:34,,302-306,,Pt 1,129,,Stud Health Technol Inform,,,,,,,,eng,,,,,,,PMID: 17911727,,,,"Humans; Computer Simulation; Systems Integration; National Health Programs; Internet; 00; Hospital Information Systems; *Medical Records Systems, Computerized; *Medical Record Linkage; Greece; Review",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HKZLWRYR,journalArticle,2007,"Horsch, Alexander; Khoshsima, Daryoush",Towards modeling and simulation of integrated social and health care services for elderly.,Studies in health technology and informatics,,0926-9630 0926-9630,,,"In order to estimate the impact of an innovation on a segment of the health care system under certain assumptions such as different possible regulatory or financing schemes (scenarios) prior to its diffusion, one must understand the dynamic behavior of the entire system with its essential control loops. Aim of this feasibility study was to explore the potential of System Dynamics (SD) modeling for this purpose. First, a UML-based modeling of an Innovative Care for Elderly (ICE) system for provision of integrated social and health care services to elderly living at home was done. Then monetary and quality of life aspects of the social and health care system were described by two coarse SD models. On these models the impact of the introduction of the ICE system under certain assumption (scenarios) was studied, based on data from the German Health Expenditure and German Federal Statistics Office. The simulations show plausible behavior, however, are not yet detailed enough for a final conclusion. A major problem is missing data for setting model parameters: estimates had to be made. In conclusion, SD modeling might be a useful method for studying impacts of the diffusion of an innovation in the health for elderly sector, but more research is needed.",2007,26/11/2018 12:52,14/04/2020 08:34,,38-42,,Pt 1,129,,Stud Health Technol Inform,,,,,,,,eng,,,,,,,PMID: 17911674,,,,"Humans; Aged; Quality of Life; Systems Analysis; Computer Simulation; *Models, Theoretical; Feasibility Studies; System dynamics; Systems Integration; Computer Systems; 1; *Information Systems; *Health Services for the Aged; Telemedicine; 220",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7K5BYUT4,journalArticle,2007,"DeVita, Michael A.",Simulation and the prognosis for the apprenticeship model of health care education.,Journal of intensive care medicine,,0885-0666 0885-0666,10.1177/0885066607304435,,,2007-10,26/11/2018 12:52,14/04/2020 08:34,,310-311,,5,22,,J Intensive Care Med,,,,,,,,eng,,,,,,,PMID: 17895489,,,,"Humans; United States; *Computer Simulation; Models, Educational; Risk Management; 00; *Education, Medical; *Educational Technology; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, K7GPV88X,journalArticle,2007,"Jenkins, Randall Carter; Lemak, Christy Harris",Innovative teaching for health law: a case study of a hospital medical malpractice lawsuit simulation.,The Journal of health administration education,,0735-6722 0735-6722,,,"In this article we describe a case study of a learning exercise for healthcare management students to more effectively understand how the legal process impacts healthcare organizations and healthcare professionals. Through a semester-long mock trial, we illustrate how healthcare executives can better understand and prepare their employees, their organization, and fellow administrators for the financial, emotional, and time investment that a lawsuit requires. Students participate as a member of the plaintiff team, defendant team, or juror in a simulated lawsuit brought by a patient against a hospital. We explain how students who participate in the simulated lawsuit gain a better understanding of difficult legal principles discussed throughout the course. We further indicate how the mock trial simulation may support achievement of current Commission on Accreditation of Healthcare Management Education (CAMHE) criteria. Next, we highlight how the mock trial allowed students to put into practice many of the health law principles discussed in class through role playing the different stages of medical malpractice trial. The article concludes with examples of how a simulated mock trial may also provide similar interdisciplinary educational, performance improvement, and cost saving benefits to healthcare professionals and their organizations.",2007,26/11/2018 12:52,14/04/2020 08:34,,43-57,,1,24,,J Health Adm Educ,,,,,,,,eng,,,,,,,PMID: 17847866,,,,Humans; United States; *Curriculum; *Diffusion of Innovation; Health Facility Administrators/*education; *Malpractice; Health Care Sector/*legislation & jurisprudence; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4RC6XX8U,journalArticle,2007,"Gohlke, Julia M.; Portier, Christopher J.",The forest for the trees: a systems approach to human health research.,Environmental health perspectives,,0091-6765 0091-6765,10.1289/ehp.10373,,"We explore the relationship between current research directions in human health and environmental and public health policy. Specifically, we suggest there is a link between the continuing emphasis in biomedical research on individualized, therapeutic solutions to human disease and the increased reliance on individual choice in response to environmental and/or public health threats. We suggest that continued research emphasis on these traditional approaches to the exclusion of other approaches will impede the discovery of important breakthroughs in human health research necessary to understand the emerging diseases of today. We recommend redirecting research programs to interdisciplinary and population-focused research that would support a systems approach to fully identifying the environmental factors that contribute to disease burden. Such an approach would be able to address the interactions between the social, ecological, and physical aspects of our environment and explicitly include these in the evaluation and management of health risks from environmental exposures.",2007-09,26/11/2018 12:52,14/04/2020 08:34,,1261-1263,,9,115,,Environ Health Perspect,,,,,,,,eng,,,,,,,PMID: 17805413 PMCID: PMC1964909,,,,Humans; Research; Environment; public health; Public Health; Animals; Public Policy; 00; *Environmental Health; risk assessment; systems biology; Systems Biology; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GDZIIJ22,journalArticle,2007,"Ying, Hao; Lin, Feng; MacArthur, Rodger D.; Cohn, Jonathan A.; Barth-Jones, Daniel C.; Ye, Hong; Crane, Lawrence R.",A self-learning fuzzy discrete event system for HIV/AIDS treatment regimen selection.,"IEEE transactions on systems, man, and cybernetics. Part B, Cybernetics : a publication of the IEEE Systems, Man, and Cybernetics Society",,1083-4419 1083-4419,,,"The U.S. Department of Health and Human Services Human Immunodeficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS) treatment guidelines are modified several times per year to reflect the rapid evolution of the field (e.g., emergence of new antiretroviral drugs). As such, a treatment-decision support system that is capable of self-learning is highly desirable. Based on the fuzzy discrete event system (FDES) theory that we recently created, we have developed a self-learning HIV/AIDS regimen selection system for the initial round of combination antiretroviral therapy, one of the most complex therapies in medicine. The system consisted of a treatment objectives classifier, fuzzy finite state machine models for treatment regimens, and a genetic-algorithm-based optimizer. Supervised learning was achieved through automatically adjusting the parameters of the models by the optimizer. We focused on the four historically popular regimens with 32 associated treatment objectives involving the four most important clinical variables (potency, adherence, adverse effects, and future drug options). The learning targets for the objectives were produced by two expert AIDS physicians on the project, and their averaged overall agreement rate was 70.6%. The system's learning ability and new regimen suitability prediction capability were tested under various conditions of clinical importance. The prediction accuracy was found between 84.4% and 100%. Finally, we retrospectively evaluated the system using 23 patients treated by 11 experienced nonexpert faculty physicians and 12 patients treated by the two experts at our AIDS Clinical Center in 2001. The overall exact agreement between the 13 physicians' selections and the system's choices was 82.9% with the agreement for the two experts being both 100%. For the seven mismatched cases, the system actually chose more appropriate regimens in four cases and equivalent regimens in another two cases. It made a mistake in one case. These (preliminary) results show that 1) the System outperformed the nonexpert physicians and 2) it performed as well as the expert physicians did. This learning and prediction approach, as well as our original FDESs theory, is general purpose and can be applied to other medical or nonmedical problems.",2007-08,26/11/2018 12:52,14/04/2020 08:35,,966-979,,4,37,,IEEE Trans Syst Man Cybern B Cybern,,,,,,,,eng,,,,,,,PMID: 17702293,,,,"Humans; Treatment Outcome; *Decision Support Systems, Clinical; *Algorithms; 00; *Fuzzy Logic; Drug Therapy, Computer-Assisted/*methods; *Artificial Intelligence; Acquired Immunodeficiency Syndrome/diagnosis/*therapy; Anti-Retroviral Agents/*administration & dosage; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HCX585BW,journalArticle,2007,"Bott, Oliver J.; Hoffmann, Ina; Bergmann, Joachim; Gusew, Nathalie; Schnell, Oliver; Gomez, Enrique J.; Hernando, M. Elena; Kosche, Patrick; von Ahn, Christian; Mattfeld, Dirk C.; Pretschner, Dietrich P.",HIS modelling and simulation based cost-benefit analysis of a telemedical system for closed-loop diabetes therapy.,International journal of medical informatics,,1872-8243 1386-5056,10.1016/j.ijmedinf.2007.06.002,,"OBJECTIVES: INCA (Intelligent Control Assistant for Diabetes) is an EU funded project aimed at improving diabetes therapy by creating a personal closed-loop system interacting with telemedical remote control. This study aims at identifying and applying suitable methods for a cost-benefit analysis from the perspective of the payor for health services. METHODS: For cost analysis MOSAIK-M was used, a method and tool for health information systems analysis and design. Two MOSAIK-M models were created describing conventional insulin pump based diabetes care (CSII), and INCA based diabetes care. Both models were parameterized with costs and simulated to determine yearly costs of diabetes management and treatment for a patient with no diabetes related complications. Probability of developing complications and their duration were determined based on the Archimedes model. It was parameterized with results of a clinical study concerning HbA1c-value changes using the INCA system compared with conventional CSII. The simulation results in form of years of disease within a 30-year time frame were multiplied with corresponding treatment costs. RESULTS: Yearly costs of conventional insulin CSII for a diabetes type 1 patient are euro 5908 (German health care system). Using INCA based on the clinical study setting would raise yearly costs by euro 2233. 24% of the INCA costs are generated by the continuous blood glucose measurement device, 5% by IT devices and services. Considering also diabetes related complications in a 30-year time frame and HbA1c value reductions from 7.9 and 7.6% (conventional CSII) to 7.5 and 7.3% (INCA) reduces the additional costs of INCA to euro 2102 and euro 2162. CONCLUSIONS: The approach produces an estimation of a lower bound for cost savings concerning the treatment of diabetes related complications in a 30-year time frame. These savings alone do not prove cost efficiency of the INCA approach. Further work is needed to improve the approximation and to include indirect and intangible costs.",2007-12,26/11/2018 12:52,14/04/2020 08:34,,S447-455,,,76 Suppl 3,,Int J Med Inform,,,,,,,,eng,,,,,,,PMID: 17656150,,,,"Humans; Cost-Benefit Analysis; Middle Aged; *Computer Simulation; *Telemedicine; 1; *Hospital Information Systems; Diabetes Mellitus, Type 1/*drug therapy/economics; Insulin Infusion Systems/economics; meta modeling; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, AMSLHGY6,journalArticle,2008,"Ahmad, Sajjad; Franz, Gregor A.",Raising taxes to reduce smoking prevalence in the US: a simulation of the anticipated health and economic impacts.,Public health,,0033-3506 0033-3506,10.1016/j.puhe.2007.02.020,,"OBJECTIVE: To estimate health and economic outcomes of raising the excise taxes on cigarettes. METHODS: We use a dynamic computer simulation model to estimate health and economic impacts of raising taxes on cigarettes (up to 100% price increase) for the entire population of the USA over 20 years. We also perform sensitivity analysis on price elasticity. RESULTS: A 40% tax-induced cigarette price increase would reduce smoking prevalence from 21% in 2004 to 15.2% in 2025 with large gains in cumulative life years (7 million) and quality adjusted life years (13 million) over 20 years. Total tax revenue will increase by $365 billion in that span, and total smoking-related medical costs would drop by $317 billion, resulting in total savings of $682 billion. These benefits increase greatly with larger tax increases, and tax revenues continue to rise even as smoking prevalence falls. CONCLUSIONS: Increasing taxes on cigarettes is a unique policy intervention that reduces smoking prevalence, generates additional tax revenue, and results in significant savings in medical care costs.",2008-01,26/11/2018 12:52,14/04/2020 08:34,,03-Oct,,1,122,,Public Health,,,,,,,,eng,,,,,,,PMID: 17610918 PMCID: PMC2246022,,,,"Humans; United States; *Computer Simulation; Quality of Life; Models, Econometric; Prevalence; Health Services/utilization; system dynamics; 1; *Health Expenditures; Smoking/*economics/legislation & jurisprudence; Taxes/*economics/legislation & jurisprudence; 220",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ASCCQIDI,journalArticle,2007,"Nishisaki, Akira; Keren, Ron; Nadkarni, Vinay","Does simulation improve patient safety? Self-efficacy, competence, operational performance, and patient safety.",Anesthesiology clinics,,1932-2275 1932-2275,10.1016/j.anclin.2007.03.009,,"Simulation training is an essential educational strategy for health care systems to improve patient safety. The strength of simulation training is its suitability for multidisciplinary team training. There is good evidence that simulation training improves provider and team self-efficacy and competence on manikins. There is also good evidence that procedural simulation improves actual operational performance in clinical settings. However, no evidence yet shows that crew resource management training through simulation, despite its promise, improves team operational performance at the bedside. Also, no evidence to date proves that simulation training actually improves patient outcome. Even so, confidence is growing in the validity of medical simulation as the training tool of the future. The use of medical simulation will continue to grow in the context of multidisciplinary team training for patient safety.",2007-06,26/11/2018 12:52,14/04/2020 08:35,,225-236,,2,25,,Anesthesiol Clin,,,,,,,,eng,,,,,,,PMID: 17574187,,,,"Humans; Treatment Outcome; *Patient Simulation; Safety; *Clinical Competence; Manikins; Patients; 00; Education, Medical/*methods; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3CY5K229,journalArticle,2007,"Milstein, Bobby; Jones, Andrew; Homer, Jack B.; Murphy, Dara; Essien, Joyce; Seville, Don",Charting plausible futures for diabetes prevalence in the United States: a role for system dynamics simulation modeling.,Preventing chronic disease,,1545-1151 1545-1151,,,"INTRODUCTION: Healthy People 2010 (HP 2010) objectives call for a 38% reduction in the prevalence of diagnosed diabetes mellitus, type 1 and type 2, by the year 2010. The process for setting this objective, however, did not focus on the achievability or the compatibility of this objective with other national public health objectives. We used a dynamic simulation model to explore plausible trajectories for diabetes prevalence in the wake of rising levels of obesity in the U.S. population. The model helps to interpret historic trends in diabetes prevalence in the United States and to anticipate plausible future trends through 2010. METHODS: We conducted simulation experiments using a computer model of diabetes population dynamics to 1) track the rates at which people develop diabetes, are diagnosed with the disease, and die, and 2) assess the effects of various preventive-care interventions. System dynamics modeling methodology based on data from multiple sources guided the analyses. RESULTS: With the number of new cases of diabetes being much greater than the number of deaths among those with the disease, the prevalence of diagnosed diabetes in the United States is likely to continue to increase. Even a 29% reduction in the number of new cases (the HP 2010 objective) would only slow the growth, not reverse it. Increased diabetes detection rates or decreased mortality rates--also HP 2010 objectives--would further increase diagnosed prevalence. CONCLUSION: The HP 2010 objective for reducing diabetes prevalence is unattainable given the historical processes that are affecting incidence, diagnosis, and mortality, and even a zero-growth future is unlikely. System dynamics modeling shows why interventions to protect against chronic diseases have only gradual effects on their diagnosed prevalence.",2007-07,26/11/2018 12:52,14/04/2020 08:34,,A52,,3,4,,Prev Chronic Dis,,,,,,,,eng,,,,,,,PMID: 17572956 PMCID: PMC1955415,,,,"Humans; Risk Factors; *Models, Biological; *Computer Simulation; United States/epidemiology; Public Health; Prevalence; Public Policy; System Dynamics; Diabetes Mellitus/*epidemiology; Longevity; 1; 220",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MCHW55HV,journalArticle,2007,"Hsieh, Michael H.; Meng, Maxwell V.; Turek, Paul J.",Markov modeling of vasectomy reversal and ART for infertility: how do obstructive interval and female partner age influence cost effectiveness?,Fertility and sterility,,1556-5653 0015-0282,10.1016/j.fertnstert.2006.11.199,,"OBJECTIVE: To apply Markov models to assess the cost effectiveness of the relative impact of obstructive interval and female partner age on fertility using either assisted reproductive technology (ART) or vasectomy reversal, and elucidate the impact of these variables on fertility. DESIGN: Markov models based on review of published literature and available ART outcome data. SETTING: University-based clinical practice. PATIENT(S): Simulation runs of 50,000 patients for each analysis. INTERVENTION(S): Varying vasectomy obstructive interval and maternal age. MAIN OUTCOME MEASURE(S): Cost effectiveness, willingness to pay (WTP), and net health benefit. RESULT(S): Base case analysis showed ART yields a higher pregnancy rate and higher cost than vasectomy reversal. Sensitivity analysis showed female age has a greater effect on cost effectiveness than obstructive interval. At a WTP < $65,000, vasectomy reversal is more cost effective than ART. With increasing WTP, ART is more cost effective over wider windows of female age. CONCLUSION(S): Markov modeling of fertility after vasectomy suggests female age has more impact than vasectomy obstructive interval on cost effectiveness.",2007-10,26/11/2018 12:52,14/04/2020 08:34,,840-846,,4,88,,Fertil Steril,,,,,,,,eng,,,,,,,PMID: 17544418,,,,"Humans; Cost-Benefit Analysis; Adult; Female; Male; Markov Chains; Computer Simulation; Pregnancy; Time Factors; Sensitivity and Specificity; Age Factors; 00; Pregnancy Rate; *Fertility; Infertility, Male/economics/*therapy; Reproductive Techniques, Assisted/*economics; Vasovasostomy/*economics; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ICKAKW8B,journalArticle,2007,"Schwenkglenks, M.; Lippuner, K.",Simulation-based cost-utility analysis of population screening-based alendronate use in Switzerland.,Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA,,0937-941X 0937-941X,10.1007/s00198-007-0390-4,,"UNLABELLED: A simulation model adopting a health system perspective showed population-based screening with DXA, followed by alendronate treatment of persons with osteoporosis, or with anamnestic fracture and osteopenia, to be cost-effective in Swiss postmenopausal women from age 70, but not in men. INTRODUCTION: We assessed the cost-effectiveness of a population-based screen-and-treat strategy for osteoporosis (DXA followed by alendronate treatment if osteoporotic, or osteopenic in the presence of fracture), compared to no intervention, from the perspective of the Swiss health care system. METHODS: A published Markov model assessed by first-order Monte Carlo simulation was refined to reflect the diagnostic process and treatment effects. Women and men entered the model at age 50. Main screening ages were 65, 75, and 85 years. Age at bone densitometry was flexible for persons fracturing before the main screening age. Realistic assumptions were made with respect to persistence with intended 5 years of alendronate treatment. The main outcome was cost per quality-adjusted life year (QALY) gained. RESULTS: In women, costs per QALY were Swiss francs (CHF) 71,000, CHF 35,000, and CHF 28,000 for the main screening ages of 65, 75, and 85 years. The threshold of CHF 50,000 per QALY was reached between main screening ages 65 and 75 years. Population-based screening was not cost-effective in men. CONCLUSION: Population-based DXA screening, followed by alendronate treatment in the presence of osteoporosis, or of fracture and osteopenia, is a cost-effective option in Swiss postmenopausal women after age 70.",2007-11,26/11/2018 12:52,14/04/2020 08:35,,1481-1491,,11,18,,Osteoporos Int,,,,,,,,eng,,,,,,,PMID: 17530156,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Female; Male; Middle Aged; Aged; Markov Chains; Health Care Costs/statistics & numerical data; Aged, 80 and over; Mass Screening/*economics; Health Services Research/methods; Sex Factors; 00; Drug Costs/statistics & numerical data; Absorptiometry, Photon/economics; Alendronate/economics/*therapeutic use; Bone Density Conservation Agents/economics/*therapeutic use; Osteoporosis, Postmenopausal/diagnosis/drug therapy/economics; Osteoporosis/diagnosis/*drug therapy/economics; Switzerland; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DHHNMBV7,journalArticle,2007,"Brandle, M.; Azoulay, M.; Greiner, R. A.",Cost-effectiveness and cost-utility of insulin glargine compared with NPH insulin based on a 10-year simulation of long-term complications with the Diabetes Mellitus Model in patients with type 2 diabetes in Switzerland.,International journal of clinical pharmacology and therapeutics,,0946-1965 0946-1965,,,"OBJECTIVE: The objective of this study was to evaluate the cost-effectiveness of insulin glargine compared with NPH insulin in patients with type 2 diabetes and in whom OAD (oral anti-diabetics) had failed in Switzerland. METHODS: Long-term diabetes outcomes were simulated with the Diabetes Mellitus Model (DMM) over a period of 10 years. The incidences of long-term complications (micro- and macrovascular events) were simulated for 10,000 patients over 10 years for six different scenarios. The scenarios were based on HbA1c reductions observed in clinical trials. For insulin glargine, HbA1c reductions of 0.96% (pessimistic case) and 1.24% (optimistic case) were simulated for three different HbA1c baseline values (10, 9 and 8%). For NPH insulin the HbA1c reduction was assumed to be 0.84%. A cost model and a utility model were developed in order to use the cumulated incidences of the simulations for the calculation of cost and QALYs (quality-adjusted life years). The unit costs of micro- and macrovascular events were assessed on the basis of published literature and guideline-projected resource-use estimations for Switzerland. Disutility values of diabetes-related long-term complications were derived from the literature. Total direct medical costs or QALYs were assessed by a combination of cumulated incidences of each event up to 10 years with the corresponding unit cost per event (in addition to the acquisition cost) or with disutility values per event, respectively. Events, total cost, and QALYs were discounted at 3%. In scenarios where no savings could be shown for insulin glargine, incremental cost-effectiveness ratios were calculated as the incremental cost per event prevented and the cost per QALY gained. RESULTS: Cost comparison demonstrated that insulin glargine is the dominant strategy for the optimistic case scenario starting at a baseline HbA1c value of 10% as savings in the management of complications exceeded the difference in acquisition costs after 8 years of treatment. Optimistic case scenarios for baseline HbA1c values of 9 and 8% achieved costs per QALY gained amounting to CHF 2,853 and CHF 5,711 and costs per event prevented amounting to CHF 2,054 and CHF 4,899, respectively. Pessimistic case scenarios for baseline HbA1c values of 10, 9 and 8% resulted in costs per QALY gained amounting to CHF 40,441, CHF 45,701 and CHF 49,468 and costs per event prevented amounting to CHF 27,742, CHF 32,451 and CHF 41,620, respectively. CONCLUSIONS: This study investigated the long-term health-economic implications of treating type 2 diabetes patients, in whom OAD had failed, with insulin glargine versus NPH insulin in Switzerland. The 10-year simulations demonstrated that the deltaHbA1c reductions of 0.4 and 0.12% achieved with insulin glargine led to a reduction of long-term complications, mortality and associated costs as well as to an improved quality of life. Insulin glargine proved to be cost-effective and represents good to excellent value for money compared to NPH insulin.",2007-04,26/11/2018 12:52,14/04/2020 08:34,,203-220,,4,45,,Int J Clin Pharmacol Ther,,,,,,,,eng,,,,,,,PMID: 17474539,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Health Care Costs; Female; Male; Middle Aged; Aged; Quality of Life; Computer Simulation; Epidemiologic Methods; 00; Hypoglycemic Agents/*economics/therapeutic use; Glycated Hemoglobin A/drug effects; Switzerland; Diabetes Mellitus, Type 2/*complications/*drug therapy/economics; Insulin Glargine; Insulin, Isophane/*economics/therapeutic use; Insulin, Long-Acting; Insulin/*analogs & derivatives/economics/therapeutic use; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WVYFGELT,journalArticle,2007,"Fuller, Jeffrey; Kelly, Brian; Sartore, Gina; Fragar, Lynne; Tonna, Anne; Pollard, Georgia; Hazell, Trevor",Use of social network analysis to describe service links for farmers' mental health.,The Australian journal of rural health,,1038-5282 1038-5282,10.1111/j.1440-1584.2007.00861.x,,"OBJECTIVE: The primary mental health care needs of farmers require that service innovations incorporate rural support workers into a local service network. This component of the FarmLink pilot sought to develop a social network analysis method that would describe local mental health-related human service networks. The purpose is to inform improvements in this network and to serve as a baseline against which such improvements can be evaluated. DESIGN: A pilot survey of rural human service providers who deal with mental health-related issues among farmers about their self-reported links between each other. SETTING: Service delivery agencies associated with a small rural town in New South Wales. PARTICIPANTS: Twenty-five agents from a range of human services involved in rural human support services to farmers, such as from agricultural and drought support, welfare, primary health care and education. INTERVENTION: Telephone interview prior to the conduct of a Mental Health First Aid seminar and a Farmers Mental Health and Wellbeing workshop. MAIN OUTCOME MEASURES: Agent self-reported service links over the past three months for information exchange, client referrals and working together in relation to helping farmers for mental health, emotional health or stress-related problems. Analysis trialled on the 'made referrals' link shows the network influence, prominence and intermediary status of the rural financial counsellor. CONCLUSIONS: Within the limitations of recalled self-report data, social network analysis provides a useful network description for informing and evaluating service network improvements.",2007-04,26/11/2018 12:52,14/04/2020 08:34,,99-106,,2,15,,Aust J Rural Health,,,,,,,,eng,,,,,,,PMID: 17441818,,,,"Humans; Health Services Accessibility; Program Evaluation; Surveys and Questionnaires; Health Services Research; Professional Role; Pilot Projects; Research Design; Data Interpretation, Statistical; Attitude of Health Personnel; Cooperative Behavior; *Interinstitutional Relations; Social Support; Community Networks/*organization & administration; 00; Referral and Consultation/*organization & administration; Rural Health Services/*organization & administration; Community Mental Health Services/*organization & administration; Workload/statistics & numerical data; Agricultural Workers' Diseases/epidemiology/therapy; Mental Disorders/epidemiology/therapy; Needs Assessment/organization & administration; New South Wales/epidemiology; Primary Health Care/organization & administration; Total Quality Management/organization & administration; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QWJKKNCA,journalArticle,2007,"Bell, Christopher; Graham, Jonathan; Earnshaw, Stephanie; Oleen-Burkey, Merrikay; Castelli-Haley, Jane; Johnson, Kenneth",Cost-effectiveness of four immunomodulatory therapies for relapsing-remitting multiple sclerosis: a Markov model based on long-term clinical data.,Journal of managed care pharmacy : JMCP,,1083-4087 1083-4087,10.18553/jmcp.2007.13.3.245,,"BACKGROUND: Before the introduction of the immunomodulatory therapies for multiple sclerosis (MS), treatment options for MS consisted of symptomatic management (physical therapy and pharmacological treatment for symptom management). Symptomatic management for MS has been supplemented in the past decade by 2 new classes of immunomodulatory therapies that have been approved as first-line treatments for relapsing-remitting multiple sclerosis (RRMS): subcutaneous glatiramer acetate (SC GA) and 3 beta-interferons: intramuscular interferon beta-1a (IM IFNbeta-1a), SC IFNbeta-1a, and SC IFNbeta-1b. OBJECTIVE: To estimate the economic outcomes of 5 treatment strategies: symptom management alone, symptom management combined with SC GA, IM IFNbeta1-a, SC IFNbeta1-a, or SC IFNbeta1-b in patients diagnosed with RRMS. METHODS: A literature-based Markov model was developed to assess the cost-effectiveness of 5 treatment strategies for managing a hypothetical cohort of patients diagnosed with RRMS in the United States--4 immunomodulatory drug therapies and symptom management alone. Health states were based on the Kurtzke Expanded Disability Status Scale (EDSS), a widely accepted scale for assessing RRMS (higher EDSS scores = increased disease severity). Baseline relapse and disease progression transition probabilities for symptom management were obtained from natural history studies. Treatment effects of the immunomodulatory therapies were estimated by applying a percentage reduction to the symptom management transition probabilities for relapse (27% reduction) and disease progression (30% reduction). Transition probabilities were subsequently adjusted to account for (1) the effects of neutralizing antibodies, specifically on relapse rates by assuming no additional therapy benefits after the second year of continuous therapy, and (2) treatment discontinuation. Therapy-specific data were obtained from clinical trials and long-term follow-up observational studies. Transitions among health states occurred in 1-month cycles for the lifetime of a patient. Costs (2005 US$) and outcomes were discounted at 3% annually. RESULTS: The incremental cost per quality-adjusted life-year for the 4 immunomodulatory therapies is $258,465, $303,968, $416,301, and $310,691 for SC GA, IM IFNbeta-1a, SC IFNbeta-1a, and SC IFNbeta-1b, respectively, compared with symptom management alone. Sensitivity analyses demonstrated that results were sensitive to changes in utilities, disease progression rates, time horizon, and immunomodulatory therapy cost. CONCLUSIONS: The pharmacoeconomic model determined that SC GA was the best strategy of the 4 immunomodulatory therapies used to manage MS and resulted in better outcomes than symptom management alone. Sensitivity analyses indicated that the model was sensitive to changes in a number of key parameters, and thus changes in these key parameters would likely influence the estimated cost-effectiveness results. Head-to-head randomized clinical trials comparing the immunomodulatory therapies for the treatment of MS are necessary to validate the projections from the pharmacoeconomic analyses, particularly since the results available today from the clinical trials do not account adequately for treatment dropouts.",2007-04,26/11/2018 12:52,14/04/2020 08:34,,245-261,,3,13,,J Manag Care Pharm,,,,,,,,eng,,,,,,,PMID: 17407391,,,,"Humans; United States; Outcome Assessment (Health Care); Cost-Benefit Analysis; Quality-Adjusted Life Years; Treatment Outcome; Health Care Costs; *Markov Chains; Drug Costs; Research Design; Time Factors; Sensitivity and Specificity; *Models, Econometric; 00; Glatiramer Acetate; Interferon beta-1a; Interferon beta-1b; Multiple Sclerosis, Relapsing-Remitting/*drug therapy/*economics; Immunologic Factors/*economics/*therapeutic use; Interferon-beta/economics/therapeutic use; Peptides/economics/therapeutic use; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VP4J3CWS,journalArticle,2007,"Shepherd, Irwyn A.; Kelly, Cherene M.; Skene, Fiona M.; White, Karin T.",Enhancing graduate nurses' health assessment knowledge and skills using low-fidelity adult human simulation.,Simulation in healthcare : journal of the Society for Simulation in Healthcare,,1559-2332 1559-2332,10.1097/SIH.0b013e318030c8dd,,"PURPOSE: Although simulation technology in nursing education is becoming increasingly commonplace, a review of the literature reveals a paucity of rigorous, high-level research comparing the effectiveness of simulation with other traditional education methods in the acquisition of clinical knowledge and skills. This research aimed to investigate the impact of three learning interventions on graduate nurse health assessment knowledge and skills. It was hypothesized that the patient assessment skills of graduate nurses who completed a simulation learning activity would be superior to those who completed traditional education activities. METHODS: Graduate nurses (n = 74) were randomly allocated to three groups (1: self-directed learning package [SDLP] only; 2: SDLP plus two scenario-based PowerPoint workshops; and 3: SDLP plus two simulation education sessions using a manikin with low-fidelity capabilities. Following the education activities, graduates completed an individual test involving a systematic patient assessment upon a manikin. They were scored using a checklist of relevant responses. RESULTS: Analysis of variance results suggest that the mean test score for nurses in the simulation group (mean = 135.52, SD = 26.63) was significantly higher (P < 0.001) than those in the learning package group (mean = 107.42, SD = 29.82) and the PowerPoint group (mean = 102.77, SD = 31.68). CONCLUSIONS: Simulation appears to be an effective educational tool for teaching patient assessment knowledge and skills to graduate nurses. Incorporation of such technology into graduate nurse education may decrease the time required to become clinically proficient, resulting in more confident and work-ready practitioners.",2007,26/11/2018 12:52,14/04/2020 08:35,,16-24,,1,2,,Simul Healthc,,,,,,,,eng,,,,,,,PMID: 19088604,,,,"Humans; Manikins; Victoria; 00; Educational Measurement/*methods; Clinical Competence/*standards; Education, Nursing, Graduate/*methods; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PLX5S2AW,journalArticle,2007,"Hjelmgren, J.; Svensson, A.; Jorgensen, E. T.; Lindemalm-Lundstam, B.; Ragnarson Tennvall, G.",Cost-effectiveness of tacrolimus ointment vs. standard treatment in patients with moderate and severe atopic dermatitis: a health-economic model simulation based on a patient survey and clinical trial data.,The British journal of dermatology,,0007-0963 0007-0963,10.1111/j.1365-2133.2006.07707.x,,"BACKGROUND: Atopic dermatitis (AD) affects health and quality of life (QoL) and also has great impact on both healthcare costs and costs to society. OBJECTIVES: The aim of the study was to analyse the cost-effectiveness of treatment with tacrolimus ointment vs. standard treatment in patients with moderate to severe AD. METHODS: A Markov simulation model was constructed capturing several key features of AD and its treatment: disease severity, treatment alternatives, and QoL. The model was populated with data from three sources: (i) efficacy data from a randomized controlled trial including patients with moderate to severe AD treated with either tacrolimus ointment or standard treatment (corticosteroids), (ii) resource utilization and QoL data from a patient survey including 161 Swedish patients with AD, and (iii) official price lists. Costs were calculated according to disease severity for the two treatment alternatives using the perspective of the Swedish healthcare sector. Two analyses were performed, one based on the quantity of medication used in the trial and one based on the survey data. The relationship between effectiveness of tacrolimus ointment and the amount of medication used was tested in sensitivity analyses. RESULTS: In the model simulations patients with severe AD treated with tacrolimus ointment experienced on average 4.6 more AD-free weeks per year than patients given standard treatment. The corresponding figure for patients with moderate AD was 6.5 more AD-free weeks per year. The cost-effectiveness ratios [cost per Quality Adjusted Life Year (QALY) gained] for treatment with tacrolimus ointment vs. standard treatment were 2,334 British pound for moderate AD and 3,875 British pound for severe AD when treatment patterns from the survey were assumed, and 8,269 British pound for moderate AD and 12,304 British pound for severe AD when treatment patterns from the clinical trial were assumed. The results of sensitivity analyses were all well within limits to be considered cost-effective. CONCLUSIONS: Estimates of the incremental cost-effectiveness ratio are far below the currently discussed threshold in Sweden, corresponding to approximately 48,700 British pound per QALY gained, and equivalent thresholds in other countries. Treatment with tacrolimus ointment in patients with moderate and severe AD can therefore be considered cost-effective.",2007-05,26/11/2018 12:52,14/04/2020 08:34,,913-921,,5,156,,Br J Dermatol,,,,,,,,eng,,,,,,,PMID: 17263826,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Health Care Costs; Adult; Female; Male; Markov Chains; Sweden; Models, Economic; 00; Immunosuppressive Agents/*economics/therapeutic use; Dermatitis, Atopic/drug therapy/*economics; Ointments; Tacrolimus/*economics/therapeutic use; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8RJ2UBWM,journalArticle,2006,"Lee, Sungjoo; Giles, Denise F.; Goldsman, David; Cook, Douglas A.; Mishra, Ninad; McCarthy, Brian",Reproductive health services discrete-event simulation.,AMIA ... Annual Symposium proceedings. AMIA Symposium,,1942-597X 1559-4076,,,"Low resource healthcare environments are often characteristic of patient flow patterns with varying patient risks, extensive patient waiting times, uneven workload distributions, and inefficient service delivery. Models from industrial and systems engineering allow for a greater examination of processes by applying discrete-event computer simulation techniques to evaluate and optimize hospital performance.",2006,26/11/2018 12:52,14/04/2020 08:34,,1001,,,,,AMIA Annu Symp Proc,,,,,,,,eng,,,,,,,PMID: 17238620 PMCID: PMC1839718,,,,"Humans; *Computer Simulation; *Models, Organizational; Software; 1; Critical Pathways; Reproductive Health Services/*organization & administration; discrete-event; 999",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, W3BS6YD9,journalArticle,2006,"Gandjour, Afschin; Weyler, Eva-Julia",Cost-effectiveness of referrals to high-volume hospitals: an analysis based on a probabilistic Markov model for hip fracture surgeries.,Health care management science,,1386-9620 1386-9620,,,"Previous studies suggest that German hospitals that perform a high volume of hip fracture surgeries have a lower mortality rate and shorter length of stay than low-volume hospitals. The goal of this paper was to determine the long-term cost-effectiveness (over 20 years) of referring hip fracture surgeries to high-volume hospitals, based on data from previous studies. From a societal perspective, the cost-effectiveness ratio was 15,530 Euro per QALY (quality-adjusted life year) (95% confidence interval 9,864-33,048 Euro), while total annual costs to the statutory health insurance amounted up to 19.6 million Euro. The referral of hip fracture surgeries to high-volume hospitals is thus likely to be cost-effective in Germany.",2006-11,26/11/2018 12:52,14/04/2020 08:34,,359-369,,4,9,,Health Care Manag Sci,,,,,,,,eng,,,,,,,PMID: 17186771,,,,Humans; Cost-Benefit Analysis; Aged; *Markov Chains; Monte Carlo Method; Germany; 1; *Referral and Consultation; *Hospitals/classification; Hip Fractures/*economics/surgery; Markov; 310,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5GWV8WR6,journalArticle,2007,"Sung, Minje; Soyer, Refik; Nhan, Nguyen",Bayesian analysis of non-homogeneous Markov chains: application to mental health data.,Statistics in medicine,,0277-6715 0277-6715,10.1002/sim.2775,,"In this paper we present a formal treatment of non-homogeneous Markov chains by introducing a hierarchical Bayesian framework. Our work is motivated by the analysis of correlated categorical data which arise in assessment of psychiatric treatment programs. In our development, we introduce a Markovian structure to describe the non-homogeneity of transition patterns. In doing so, we introduce a logistic regression set-up for Markov chains and incorporate covariates in our model. We present a Bayesian model using Markov chain Monte Carlo methods and develop inference procedures to address issues encountered in the analyses of data from psychiatric treatment programs. Our model and inference procedures are implemented to some real data from a psychiatric treatment study.",10/07/2007,26/11/2018 12:52,14/04/2020 08:35,,3000-3017,,15,26,,Stat Med,,,,,,,,eng,"Copyright 2006 John Wiley & Sons, Ltd.",,,,,,PMID: 17173342,,,,Humans; Child; *Markov Chains; Adolescent; Monte Carlo Method; *Bayes Theorem; 00; Mental Health; Mental Disorders/*therapy; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4LUWWHSE,journalArticle,2006,"Ivanov, V. K.; Tsyb, A. F.; Agapov, A. M.; Panfilov, A. P.; Kaidalov, O. V.; Gorski, A. I.; Maksioutov, M. A.; Suspitsin, Y. V.; Vaizer, V. I.",Concept of optimisation of the radiation protection system in the nuclear sector: management of individual cancer risks and providing targeted health care.,Journal of radiological protection : official journal of the Society for Radiological Protection,,0952-4746 0952-4746,10.1088/0952-4746/26/4/001,,"The paper discusses the provision of targeted health care to nuclear workers in Russia based on radiation-epidemiological estimates of cancer risks. Cancer incidence rates are analysed for the workers of the Institute of Physical Power Engineering (the first nuclear installation in the world) who were subjected to individual dosimetric monitoring from 1950 to 2002. The value of excess relative risk for solid cancers was found to be ERR Gy(-1) = 0.24 (95% CI: -4.22; 7.96). It has been shown that 81.8% of the persons covered by individual dosimetric monitoring have potential attributive risk up to 5%, and the risk is more than 10% for 3.7% of the workers. Among the detected cancer cases, 73.5% of the individuals show an attributive risk up to 5% and the risk is in excess of 10% for 3.9% of the workers. Principles for the provision of targeted health care, given voluntary health insurance, are outlined.",2006-12,26/11/2018 12:52,14/04/2020 08:34,,361-374,,4,26,,J Radiol Prot,,,,,,,,eng,,,,,,,PMID: 17146121,,,,"Delivery of Health Care/*organization & administration; Humans; Risk Factors; Incidence; Quality Assurance, Health Care/*organization & administration; Risk Assessment/*methods; Russia/epidemiology; Radiation Dosage; 00; Body Burden; Neoplasms, Radiation-Induced/*epidemiology; Nuclear Reactors/*statistics & numerical data; Radiation Monitoring/*statistics & numerical data; Radiation Protection/*methods; Relative Biological Effectiveness; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KNCHJGUA,journalArticle,2006,"Bott, Oliver J.; Hoffmann, Ina; Bergmann, Joachim; Kosche, Patrick; von Ahn, Christian; Mattfeld, Dirk C.; Schnell, Oliver; Pretschner, Dietrich P.",Simulation based cost-benefit analysis of a telemedical system for closed-loop insulin pump therapy of diabetes.,Studies in health technology and informatics,,0926-9630 0926-9630,,,"BACKGROUND: INCA (Intelligent Control Assistant for Diabetes) is a project funded by the EU with the objective to improve diabetes therapy by creating a personal closed loop system interacting with telemedical remote control. Cost-benefit analyses of such systems are needed to decide on the introduction of telemedical systems such as the INCA system to routine care. OBJECTIVE: To identify and apply suitable methods for a cost-benefit analysis from the perspective of the payor for health services (i.e. a health insurance company). METHODS: For the cost analysis MOSAIK-M was used, a method and tool that supports health information systems analysis and design. Two MOSAIK-M models were created during the INCA project. Both, the ""As is""-model of conventional insulin pump based diabetes care, and the ""To be""-model of the INCA system were parameterised with cost values. With both models a period of one year was simulated to determine the yearly costs of diabetes management and treatment for a patient who does not suffer from diabetes related complications yet. The HbA1c-value was chosen as effectiveness parameter for diabetes therapy. To determine the probability of developing complications and their probable duration the Archimedes-Model was used. It was parameterised with selected HbA1c-values anticipating the effect of INCA. The simulation results in form of years of disease within a 30-years time frame were multiplied with corresponding treatment costs from the KoDiM study. RESULTS: The yearly costs of conventional insulin pump treatment for a 19 year old diabetes type 1 patient with no complications are 5,907 euro (German health care system). Using the INCA system would raise the yearly costs by 7,348 euro. Almost all (98.53%) of the additional costs are generated by the continuous blood glucose measurement device. HbA1c-decreases from 7% (conventional treatment) to 6.5%, 6%, and 5.8 % would produce yearly savings (benefit) concerning the treatment of complications of 100.50 euro, 189.20 euro and 221.82 euro. CONCLUSIONS: The selected approach produces an estimation of a lower bound for cost savings. Further work is needed to improve the approximation and to include indirect and intangible costs. The INCA approach would be cost efficient from the chosen perspective, only if the costs of system operation were notably lowered.",2006,26/11/2018 12:52,14/04/2020 08:34,,435-440,,,124,,Stud Health Technol Inform,,,,,,,,eng,,,,,,,PMID: 17108558,,,,Humans; Cost-Benefit Analysis; *Telemedicine; Europe; 1; Insulin Infusion Systems/*economics; Diabetes Mellitus/*therapy; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IHKPDE9R,journalArticle,2006,"Ozar, David T.",Applying systems thinking to oral health care: Commentary on Dr. Patricia H. Werhane's article.,Journal of dental education,,0022-0337 0022-0337,,,,2006-11,26/11/2018 12:52,14/04/2020 08:35,,1196-1197,,11,70,,J Dent Educ,,,,,,,,eng,,,,,,,PMID: 17106033,,,,"Humans; United States; Social Responsibility; Professional Role; *Systems Integration; 00; Social Justice; *Ethics, Dental; Dental Care/*ethics; Health Services Accessibility/*ethics; Human Rights; Moral Obligations; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5X2GCPMC,journalArticle,2006,"Werhane, Patricia H.","Access, responsibility, and funding: A systems thinking approach to universal access to oral health.",Journal of dental education,,0022-0337 0022-0337,,,"Universal access to oral health care is a justifiable demand for a number of disparate but morally sound reasons. Nevertheless, that conclusion, however reached, has not solved the problem of the lack of access. Market forces, scarcity of funding, and lack of clarity as to who is responsible for ensuring that oral care is available seem to present insurmountable difficulties. I shall argue that these are not irresolvable problems, but the resolution has to take place through the tool of systems thinking and a systemic approach to moral imagination. Taking the lead from Susan Wolf's and Linda Emanuel's work on systems thinking, and developing ideas from work on mental models and moral imagination, I shall argue that what is often missing in discussions and demands for universal access to oral health care is a morally imaginative systemic approach that takes into account the multi-perspective dynamics involved in health care today. Moral imagination may encourage sound, broad-based, more inclusive moral thinking and moral judgment without ignoring the critical roles and responsibilities each of us has as professionals, providers, payers, or patients, without which change will not take place at all.",2006-11,26/11/2018 12:52,14/04/2020 08:35,,1184-1195,,11,70,,J Dent Educ,,,,,,,,eng,,,,,,,PMID: 17106032,,,,"Humans; United States; Social Responsibility; Professional Role; Financing, Organized; *Systems Integration; 00; Poverty; Social Justice; *Ethics, Dental; Human Rights; Moral Obligations; Dental Care/economics/*ethics/*organization & administration; Health Priorities/*ethics; Health Services Accessibility/economics/*ethics; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, L7KEYPD9,journalArticle,2006,"Jackson, Fatimah L. C.",Illuminating cancer health disparities using ethnogenetic layering (EL) and phenotype segregation network analysis (PSNA).,Journal of cancer education : the official journal of the American Association for Cancer Education,,0885-8195 0885-8195,10.1207/s15430154jce2101s_13,,"BACKGROUND: Resolving cancer health disparities continues to befuddle simplistic racial models. The racial groups alluded to in biomedicine, public health, and epidemiology are often profoundly substructured. METHODS: EL and PSNA are computational assisted techniques that focus on microethnic group (MEG) substructure. RESULTS: Geographical variations in cancer may be due to differences in MEG ancestry or similar environmental exposures to a recognized carcinogen. Examples include breast and prostate cancers in the Chesapeake Bay region and Bight of Biafra biological ancestry, hypertension and stroke in the Carolina Coast region and Central African biological ancestry, and pancreatic cancer in the Mississippi Delta region and dietary/medicinal exposure to safrol from Sassafras albidum.",2006,26/11/2018 12:52,14/04/2020 08:34,,S69-79,,1 Suppl,21,,J Cancer Educ,,,,,,,,eng,,,,,,,PMID: 17020506,,,,"Humans; Ethnic Groups/*statistics & numerical data; 00; Cultural Diversity; Genetic Predisposition to Disease; *Phenotype; Continental Population Groups/statistics & numerical data; Indians, North American/statistics & numerical data; Mid-Atlantic Region/epidemiology; Mississippi/epidemiology; Neoplasms/epidemiology/*ethnology/*genetics; Prejudice; Southeastern United States/epidemiology; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8F6V9XQJ,journalArticle,2006,"Kyrkjebo, Jane Mikkelsen; Brattebo, Guttorm; Smith-Strom, Hilde",Improving patient safety by using interprofessional simulation training in health professional education.,Journal of interprofessional care,,1356-1820 1356-1820,10.1080/13561820600918200,,"Modern medicine is complex. Reports and surveys demonstrate that patient safety is a major problem. Health educators focus on professional knowledge and less on how to improve patient care and safety. The ability to act as part of a team, fostering communication, co-operation and leadership is seldom found in health education. This paper reports the findings from pilot testing a simulated training program in interprofessional student teams. Four teams each comprising one medical, nursing, and intensive nursing student (n = 12), were exposed to two simulation scenarios twice. Focus groups were used to evaluate the program. The findings suggest that the students were satisfied with the program, but some of the videos and simulation exercises could be more realistic and more in accordance with each other. Generally they wanted more interprofessional team training, and had learned a lot about their own team performance, personal reactions and lack of certain competencies. Involving students in interprofessional team training seem to be more likely to enhance their learning process. The students' struggles with roles, competence and team skills underline the need for more focus on combining professional knowledge learning with team training.",2006-10,20/11/2018 14:34,14/04/2020 08:44,,507-516,,5,20,,J Interprof Care,,,,,,,,eng,,,,,,,PMID: 17000476,,,,"Humans; *Patient Simulation; Interprofessional Relations; Safety Management/*organization & administration; Safety; *Interprofessional Relations; Quality Assurance, Health Care/*organization & administration; Patient Simulation; Nursing; Education; Medical; Graduate; Quality Assurance – Administration; 00; Education, Nursing, Graduate/*methods; Education, Medical, Graduate/*methods; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EN32MUU6,journalArticle,2006,"Jones, S.; Faulkner, G.; Raboud, D.; Fyfe, K.; Wolfaardt, J.","Simulation of impact test for determining ""health"" of percutaneous bone anchored implants.",Journal of biomechanical engineering,,0148-0731 0148-0731,10.1115/1.2241685,,"There is an ongoing requirement for a clinically relevant, noninvasive technique to monitor the integrity of percutaneous implants used for dental restorations, bone-anchored hearing aids, and to retain extra-oral prostheses (ear, eye, nose, etc). Because of the limitations of conventional diagnostic techniques (CT, MRI), mechanical techniques that measure the dynamic response of the implant-abutment system are being developed. This paper documents a finite element analysis that simulates a transient response to mechanical impact testing using contact elements. The detailed model allows for a specific interface between the implant and bone and characterizes potential clinical situations including loss of bone margin height, loss of osseointegration, and development of a soft connective tissue layer at the bone-implant interface. The results also show that the expected difference in interface stiffness between soft connective tissue and osseointegrated bone will cause easily measurable changes in the response of the implant/abutment system. With respect to the loss of bone margin height, changes in the order of 0.2 mm should be detectable, suggesting that this technique is at least as sensitive as radiography. A partial loss of osseointegration, while not being as readily evident as a bone margin loss, would still be detectable for losses as small as 0.5 mm.",2006-10,26/11/2018 12:52,14/04/2020 08:34,,647-653,,5,128,,J Biomech Eng,,,,,,,,eng,,,,,,,PMID: 16995750,,,,"Humans; *Models, Biological; Computer Simulation; 00; *Dental Implants; Equipment Failure Analysis/*methods; Jaw/*physiopathology/surgery; Physical Stimulation/*methods; Stress, Mechanical; Vibration; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JTFEFM5L,journalArticle,2006,"Landry, Michael; Oberleitner, Melinda G.; Landry, Heidi; Borazjani, June G.",Education and practice collaboration: using simulation and virtual reality technology to assess continuing nurse competency in the long-term acute care setting.,Journal for nurses in staff development : JNSD : official journal of the National Nursing Staff Development Organization,,1098-7886 1098-7886,,,"Assessment of continuing competence of staff is a challenge for many healthcare organizations. There is no clear consensus as to what constitutes continuing competence or how to measure that competence. Methods for assessing continued competence of nurses are varied. A novel method, simulation and virtual reality technology, was used to assess the competency of nurses employed in long-term acute care hospitals in Louisiana. This article will describe the project which was the result of a collaborative effort between a large healthcare organization and a school of nursing.",2006-08,26/11/2018 12:52,14/04/2020 08:34,,163-9; quiz 170-171,,4,22,,J Nurses Staff Dev,,,,,,,,eng,,,,,,,PMID: 16885679,,,,"Humans; Program Evaluation; Clinical Competence; *Interinstitutional Relations; *User-Computer Interface; *Educational Measurement; 00; Louisiana; *Community Health Services; *Education, Nursing, Continuing/methods/organization & administration; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IEJ8J5PJ,journalArticle,2005,"Chu, Yuan-chia; Kuo, Yu-yin; Chang, Tsuei-rung; Chou, Chih-Chuan; Feng, Rung-chuang; Chang, Polun",SIGMA simulation for health promotion management.,AMIA ... Annual Symposium proceedings. AMIA Symposium,,1942-597X 1559-4076,,,"Health promotion is the key task to achieve global health 2010. Periodical physical check-up have been the most basic manifestation for maintaining personal health care and promotion inverted exclamation markC Sufficient health check facility was provided in a medical center with annual service of 9200~9500. Sixty customers receive around 20 check ups in this physical check up center daily. Smoothness, efficacy and customer satisfaction of the process will be caretakers inverted exclamation mark| concern and target for promotion.",2005,26/11/2018 12:52,14/04/2020 08:34,,926,,,,,AMIA Annu Symp Proc,,,,,,,,eng,,,,,,,PMID: 16779214 PMCID: PMC1560530,,,,"Humans; *Health Promotion; 00; *Management Information Systems; Medical Records Systems, Computerized; Physical Examination; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 5WUCCS8Z,journalArticle,2006,"Polk, Donna M.; Watson, Karol",Hospital discharge treatments after an acute event: evidence for a systems approach to prevention.,Coronary artery disease,,0954-6928 0954-6928,,,"Hospitalization and rehospitalization for acute coronary syndromes significantly contribute to the rising annual cost of healthcare. Despite growing evidence of the effectiveness of early and aggressive treatment of cardiovascular risk factors at the time of an acute event, eligible individuals are still not receiving adequate therapy. Inclusion of appropriate coronary artery disease treatments including lipid-lowering therapy at the time of hospitalization can lead to increased long-term compliance and reduced morbidity and mortality.",2006-05,26/11/2018 12:52,14/04/2020 08:35,,239-241,,3,17,,Coron Artery Dis,,,,,,,,eng,,,,,,,PMID: 16728873,,,,"Humans; Evidence-Based Medicine; Risk Factors; Patient Compliance; Health Knowledge, Attitudes, Practice; Clinical Trials as Topic; Acute Disease; *Patient Discharge; Cardiovascular Diseases/epidemiology/prevention & control/*therapy; Patient Readmission; 1; System thinking; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BR6FNNI8,journalArticle,2006,"Killingsworth, Brenda; Newkirk, Henry E.; Seeman, Elaine",An integrative health information systems approach for facilitating strategic planning in hospitals.,Health care management review,,0361-6274 0361-6274,,,"This article presents a framework for developing strategic information systems (SISs) for hospitals. It proposes a SIS formulation process which incorporates complexity theory, strategic/organizational analysis theory, and conventional MIS development concepts. Within the formulation process, four dimensions of SIS are proposed as well as an implementation plan. A major contribution of this article is the development of a hospital SIS framework which permits an organization to fluidly respond to external, interorganizational, and intraorganizational influences. In addition, this article offers a checklist which managers can utilize in developing an SIS in health care.",2006-06,26/11/2018 12:52,14/04/2020 08:34,,119-129,,2,31,,Health Care Manage Rev,,,,,,,,eng,,,,,,,PMID: 16648691,,,,"Humans; *Systems Analysis; Program Development; Models, Organizational; Guidelines as Topic; Organizational Objectives; Planning Techniques; *Systems Integration; *Decision Support Systems, Management; 00; Delivery of Health Care, Integrated/organization & administration; Health Services Accessibility/organization & administration; Hospital Information Systems/*organization & administration; Hospital Planning/*methods; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QFPWZHYL,journalArticle,2006,"Bala, Mohan V.; Mauskopf, Josephine A.",Optimal assignment of treatments to health states using a Markov decision model: an introduction to basic concepts.,PharmacoEconomics,,1170-7690 1170-7690,10.2165/00019053-200624040-00005,,"Assessing the cost effectiveness of a new health intervention often requires modelling to estimate the impact of the intervention on cost, survival and quality of life over the lifetime of a cohort of patients. Markov modelling is a methodology that is commonly employed to estimate these long-term costs and benefits. As commonly used, these models assume that the patients continue to get the treatments assigned regardless of the change in health states. In this paper, we describe an extension to the Markov modelling approach, called Markov decision modelling. Such a model starts with a set of health states and treatments and optimally assigns treatments to each of the health states. A Markov decision model can be used to identify the optimal treatment strategy not just for the initial disease state, but also as the disease state changes over time. We present a dynamic programming approach to identifying the optimal assignment of treatments, and illustrate this methodology using an example. The Markov decision modelling approach provides an efficient way of identifying optimal assignment of treatments to health states, but, like the standard Markov model, may be of limited use when probabilities of future events depend on past history in a complex fashion. Even with its limitations, Markov decision models offer an opportunity for health economists to inform healthcare decision-makers on how to modify current treatment pathways to incorporate new treatments as they become available.",2006,26/11/2018 12:52,14/04/2020 08:34,,345-354,,4,24,,Pharmacoeconomics,,,,,,,,eng,,,,,,,PMID: 16605281,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; *Models, Economic; Markov Chains; *Health Care Costs; Time Factors; *Decision Support Techniques; CD4 Lymphocyte Count; 00; *Insurance, Health; *Insurance Coverage; Health Care Rationing; HIV Infections/drug therapy/economics/immunology; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, SSZYXU85,journalArticle,2006,"Diel, R.; Nienhaus, A.; Lange, C.; Schaberg, T.",Cost-optimisation of screening for latent tuberculosis in close contacts.,The European respiratory journal,,0903-1936 0903-1936,10.1183/09031936.06.00011806,,"The aim of the present study was to perform cost-minimisation analysis of contact investigation from a public health perspective using the tuberculin skin test (TST) and a new blood assay, QuantiFERON-TB Gold (QFT-G). A decision-analysis model simulated the costs of investigating a cohort of adult close tuberculosis contacts by the public health service following the current German guidelines over a period of 2 yrs. The economic outcomes were compared with alternative screening strategies. These were: 1) QFT-G instead of TST; 2) TST followed by",2006-07,26/11/2018 12:52,14/04/2020 08:34,,35-44,,1,28,,Eur Respir J,,,,,,,,eng,,,,,,,PMID: 16571615,,,,"Humans; Cost-Benefit Analysis; Decision Support Techniques; Public Health; Sensitivity and Specificity; Mass Screening/*economics/methods; 00; Antigens, Bacterial/metabolism; BCG Vaccine; Hematologic Tests/economics/*methods; Interferon-gamma/metabolism; Mycobacterium tuberculosis/*metabolism; Tuberculin Test/economics/*methods; Tuberculosis/*diagnosis/*economics; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 36ULPA2H,journalArticle,2006,"Dong, Hengjin; Buxton, Martin",Early assessment of the likely cost-effectiveness of a new technology: A Markov model with probabilistic sensitivity analysis of computer-assisted total knee replacement.,International journal of technology assessment in health care,,0266-4623 0266-4623,10.1017/S0266462306051014,,"OBJECTIVES: The objective of this study is to apply a Markov model to compare cost-effectiveness of total knee replacement (TKR) using computer-assisted surgery (CAS) with that of TKR using a conventional manual method in the absence of formal clinical trial evidence. METHODS: A structured search was carried out to identify evidence relating to the clinical outcome, cost, and effectiveness of TKR. Nine Markov states were identified based on the progress of the disease after TKR. Effectiveness was expressed by quality-adjusted life years (QALYs). The simulation was carried out initially for 120 cycles of a month each, starting with 1,000 TKRs. A discount rate of 3.5 percent was used for both cost and effectiveness in the incremental cost-effectiveness analysis. Then, a probabilistic sensitivity analysis was carried out using a Monte Carlo approach with 10,000 iterations. RESULTS: Computer-assisted TKR was a long-term cost-effective technology, but the QALYs gained were small. After the first 2 years, the incremental cost per QALY of computer-assisted TKR was dominant because of cheaper and more QALYs. The incremental cost-effectiveness ratio (ICER) was sensitive to the ""effect of CAS,"" to the CAS extra cost, and to the utility of the state ""Normal health after primary TKR,"" but it was not sensitive to utilities of other Markov states. Both probabilistic and deterministic analyses produced similar cumulative serious or minor complication rates and complex or simple revision rates. They also produced similar ICERs. CONCLUSIONS: Compared with conventional TKR, computer-assisted TKR is a cost-saving technology in the long-term and may offer small additional QALYs. The ""effect of CAS"" is to reduce revision rates and complications through more accurate and precise alignment, and although the conclusions from the model, even when allowing for a full probabilistic analysis of uncertainty, are clear, the ""effect of CAS"" on the rate of revisions awaits long-term clinical evidence.",2006,26/11/2018 12:53,14/04/2020 08:34,,191-202,,2,22,,Int J Technol Assess Health Care,,,,,,,,eng,,,,,,,PMID: 16571195,,,,"Humans; Cost-Benefit Analysis; Quality of Life; *Markov Chains; Monte Carlo Method; Arthroplasty, Replacement, Knee/*economics/*statistics & numerical data; Surgery, Computer-Assisted/*economics/*statistics & numerical data; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, D5HM2QKW,journalArticle,2006,"Payne-Sturges, Devon; Zenick, Harold; Wells, Charles; Sanders, William",We cannot do it alone: Building a multi-systems approach for assessing and eliminating environmental health disparities.,Environmental research,,0013-9351 0013-9351,10.1016/j.envres.2006.01.011,,,2006-10,26/11/2018 12:53,14/04/2020 08:35,,141-145,,2,102,,Environ Res,,,,,,,,eng,,,,,,,PMID: 16545364,,,,Humans; Interdisciplinary Communication; Education; *Socioeconomic Factors; Continental Population Groups; 00; *Environmental Exposure; *Environmental Health/education; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PHLLWAG8,journalArticle,2006,"Norton, Edward C.; Yoon, Jangho; Domino, Marisa Elena; Morrissey, Joseph P.",Transitions between the public mental health system and jail for persons with severe mental illness: a Markov analysis.,Health economics,,1057-9230 1057-9230,10.1002/hec.1100,,"Proposed changes to the mental health care system are usually debated in terms of either health benefits or costs savings. However, because of the extensive intersection between the mental health system and the criminal justice system, changes in the organization and financing of mental health services may change the jail detention rate. We analyze jail incarcerations for felonies and non-felonies following the start of a public managed mental health care program in King County, Washington (including Seattle). We analyze unique data that tracks individuals in and out of the public mental health, Medicaid, and criminal justice systems for 1993-1998. In this manuscript we examine individuals with severe mental illness who were enrolled in the Washington state Medicaid program. The final sample size has monthly observations on 6766 unique individuals aged",2006-07,26/11/2018 12:53,14/04/2020 08:35,,719-733,,7,15,,Health Econ,,,,,,,,eng,,,,,,,PMID: 16541394,,,,Humans; Adult; Female; Male; Middle Aged; *Markov Chains; Adolescent; Acute Disease; 00; Medicaid; *Mental Disorders; *Public Sector; Mental Health Services/*utilization; Prisoners/*psychology; Prisons/*utilization; Washington; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 42RNPBUJ,journalArticle,2006,"Bolin, Kristian; Lindgren, Bjorn; Willers, Stefan",The cost utility of bupropion in smoking cessation health programs: simulation model results for Sweden.,Chest,,0012-3692 0012-3692,10.1378/chest.129.3.651,,"STUDY OBJECTIVES: To calculate incremental cost-utility ratios (cost per quality-adjusted life-year [QALY] gained) for bupropion (Zyban; GlaxoSmithKline; Gothenburg, Sweden), as compared to nicotine replacement therapy (NRT) in smoking cessation programs for a follow-up period of 20 years. DESIGN: The Global Health Outcomes simulation model was used for a male cohort and for a female cohort as a point of departure but was further extended in order to include the following: (1) the indirect effects of smoking cessation on production and consumption in the economy, and (2) morbidity-specific QALYs gained. SETTING: Sweden in 2001. PATIENTS OR PARTICIPANTS: Model cohort consisting of 612,851 male and 780,970 female smokers, distributed by age, > or = 35 years old, as in the Swedish population of 2001. INTERVENTIONS: Bupropion, as compared to NRT (nicotine patches and nicotine gums), in smoking cessation programs for a follow-up period of 20 years. MEASUREMENTS AND RESULTS: When the indirect effects on production and consumption were taken into account, bupropion was cost saving in comparison to both NRTs. When only the direct costs were included, bupropion was still cost saving in comparison to nicotine gum. The incremental costs per QALY gained were relatively low for bupropion in comparison to nicotine patches, 6,600 Swedish kronas (SEK) (approximately 725 euro) per QALY gained for men and 4,900 SEK (approximately 535 euro) for women, all calculations in 2001 Swedish prices. The comprehensive sensitivity analysis showed robust results; results were, however, more sensitive to quit rates and intervention costs than to other variables. CONCLUSIONS: Bupropion is a cost-effective therapy in smoking cessation programs. Furthermore, recent studies report even higher effectiveness in terms of quit rates than was assumed here, indicating that our estimated cost-utility ratio should be even more favorable to bupropion.",2006-03,26/11/2018 12:53,14/04/2020 08:34,,651-660,,3,129,,Chest,,,,,,,,eng,,,,,,,PMID: 16537864,,,,Humans; Cost-Benefit Analysis; Adult; Female; Male; Middle Aged; *Quality-Adjusted Life Years; Aged; Sweden; Smoking Cessation/*economics/methods; Stroke/epidemiology; 00; Lung Neoplasms/epidemiology; Bupropion/*economics; Chewing Gum; Dopamine Uptake Inhibitors/*economics; Heart Failure/epidemiology; Nicotine/administration & dosage; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, AI86YJ7C,journalArticle,2005,"Kongsakon, Ronnachai; Leelahanaj, Thawatchai; Price, Natalia; Birinyi-Strachan, Liesl; Davey, Peter","Cost analysis of the treatment of schizophrenia in Thailand: a simulation model comparing olanzapine, risperidone, quetiapine, ziprasidone and haloperidol.",Journal of the Medical Association of Thailand = Chotmaihet thangphaet,,0125-2208 0125-2208,,,"OBJECTIVES: To compare the annual costs of treating schizophrenia with four atypical antipsychotics-olanzapine, risperidone, quetiapine and ziprasidone and one typical antipsychotic: haloperidol in Thailand MATERIAL AND METHOD: The present study used a cost analysis model. The model simulated treatment of schizophrenics for 12 months with the data from international literature review. A comprehensive search of pharmacoeconomic literature was carried out in order to identify studies to be included in the present review. Model parameter used data from the searches of 1175 publications but merely 31 of them were relevant to the objectives of the present study. Costs associated with olanzapine, risperidone, quetiapine, ziprasidone and haloperidol therapy were calculated over a period of",2005-09,26/11/2018 12:53,14/04/2020 08:34,,1267-1277,,9,88,,J Med Assoc Thai,,,,,,,,eng,,,,,,,PMID: 16536115,,,,"Humans; Cost-Benefit Analysis; Treatment Outcome; Health Care Costs; Drug Costs; Computer Simulation; Cost of Illness; Models, Econometric; 00; Thailand; Schizophrenia/*drug therapy/*economics; Dibenzothiazepines/economics/*therapeutic use; Quetiapine Fumarate; Antipsychotic Agents/classification/economics/*therapeutic use; Benzodiazepines/economics/therapeutic use; Haloperidol/economics/*therapeutic use; Piperazines/economics/*therapeutic use; Risperidone/economics/*therapeutic use; Thiazoles/economics/*therapeutic use; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PIRYW4GI,journalArticle,2006,"Ye, Chun-Yuan; Lee, Jie-Min; Chen, Sheng-Hong",Economic gains and health benefits from a new cigarette tax scheme in Taiwan: a simulation using the CGE model.,BMC public health,,1471-2458 1471-2458,10.1186/1471-2458-6-62,,"BACKGROUND: This study evaluates the impact of an increase in cigarette tax in Taiwan in terms of the effects it has on the overall economy and the health benefits that it brings. METHODS: The multisector computable general equilibrium (CGE) model was used to simulate the impact of reduced cigarette consumption resulting from a new tax scheme on the entire economy gains and on health benefits. RESULTS: The results predict that because of the new tax scheme, there should be a marked reduction in cigarette consumption but a notable increase in health benefits that include saving between 28,125 and 56,250 lives. This could save NTD 1.222 approximately 2.445 billion (where USD 1 = NTD 34.6) annually in life-threatening, cigarette-related health insurance expenses which exceeds the projected decrease of NTD 1.275 billion in Gross Domestic Product (GDP) because of reduced consumption and therefore tax revenue. CONCLUSION: Overall, the increased cigarette excise tax will be beneficial in terms of both the health of the general public and the economy as a whole.",10/03/2006,26/11/2018 12:53,14/04/2020 08:35,,62,,,6,,BMC Public Health,,,,,,,,eng,,,,,,,PMID: 16529653 PMCID: PMC1459137,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Health Care Costs; Adult; Middle Aged; *Models, Economic; Cost of Illness; Taiwan/epidemiology; 1; *Occupational Health; Insurance, Health, Reimbursement; Efficiency; Public Health/economics/*trends; Smoking/adverse effects/*economics/epidemiology; Social Welfare/economics/*trends; Taxes/*legislation & jurisprudence; Tobacco Industry/economics/*legislation & jurisprudence; computable general equilibrium; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ZFEMUJR8,journalArticle,2006,"Mitnitski, Arnold; Bao, Le; Rockwood, Kenneth","Going from bad to worse: a stochastic model of transitions in deficit accumulation, in relation to mortality.",Mechanisms of ageing and development,,0047-6374 0047-6374,10.1016/j.mad.2006.01.007,,"As people age, they accumulate deficits. The more deficits they accumulate, the greater their vulnerability, which can be expressed as the probability to accumulate even more deficits, or to die. The probability of death is known to be exponentially related to the number of deficits. Using data from elderly (aged 65 + years) participants in the Canadian Study of Health and Aging (n = 9008), we investigated the relationship between the number of deficits and the change in the number of deficits over two successive 5 year intervals. We show that the probabilities of changes in the number of deficits, in relation to baseline, are well fitted (R(2) > 0.98) by a simple distribution, with two parameters. The model suggests a maximum to deficit accumulation, and illustrates no level of deficit accumulation at which there is a net gain in fitness. Age-related deficit accumulation is highly characteristic, and can be modeled as a stochastic process with readily interpretable parameters.",2006-05,26/11/2018 12:53,14/04/2020 08:34,,490-493,,5,127,,Mech Ageing Dev,,,,,,,,eng,,,,,,,PMID: 16519921,,,,"Humans; Aged; Markov Chains; Computer Simulation; Models, Theoretical; Models, Statistical; Risk; Health Status; *Aging; Models, Biological; Stochastic Processes; Survival Analysis; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TUV93H8R,journalArticle,2006,"Jones, Andrew P.; Homer, Jack B.; Murphy, Dara L.; Essien, Joyce D. K.; Milstein, Bobby; Seville, Donald A.",Understanding diabetes population dynamics through simulation modeling and experimentation.,American journal of public health,,0090-0036 0090-0036,10.2105/AJPH.2005.063529,,"Health planners in the Division of Diabetes Translation and others from the National Center for Chronic Disease Prevention and Health Promotion of the Centers for Disease Control and Prevention used system dynamics simulation modeling to gain a better understanding of diabetes population dynamics and to explore implications for public health strategy. A model was developed to explain the growth of diabetes since 1980 and portray possible futures through 2050. The model simulations suggest characteristic dynamics of the diabetes population, including unintended increases in diabetes prevalence due to diabetes control, the inability of diabetes control efforts alone to reduce diabetes-related deaths in the long term, and significant delays between primary prevention efforts and downstream improvements in diabetes outcomes.",2006-03,26/11/2018 12:53,14/04/2020 08:34,,488-494,,3,96,,Am J Public Health,,,,,,,,eng,,,,,,,PMID: 16449587 PMCID: PMC1470507,,,,"Humans; *Models, Statistical; system dynamics; 1; *Population Dynamics; Diabetes Complications/epidemiology/prevention & control; Diabetes Mellitus/*epidemiology/therapy; Obesity/complications; Prediabetic State/diagnosis; 220",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MI7PFCSX,journalArticle,2006,"Cadilhac, Dominique A.; Moodie, Marjory L.; Lalor, Erin E.; Bilney, Lucinda E.; Donnan, Geoffrey A.",Improving access to evidence-based acute stroke services: development and evaluation of a health systems model to address equity of access issues.,Australian health review : a publication of the Australian Hospital Association,,0156-5788 0156-5788,,,"Level 1 evidence for management of patients with stroke in a dedicated Stroke Care Unit (SCU) demonstrates improved outcomes by about 20%. It has been estimated that 21% of Australian hospitals provide an SCU and that these SCUs are mainly located in either metropolitan sites and/or in hospitals with more than 300 beds. To address equity issues related to access to SCUs, the National Stroke Foundation and the Australian Government undertook the National Stroke Units Program. One program outcome was the development of a conceptual model of acute stroke service delivery. The development process and initial evaluation of the model are described. Use of the model to increase capacity within the health care system to treat stroke is discussed.",2006-02,26/11/2018 12:53,14/04/2020 08:34,,109-118,,1,30,,Aust Health Rev,,,,,,,,eng,,,,,,,PMID: 16448383,,,,"Humans; *Models, Organizational; Australia; *Evidence-Based Medicine; National Health Programs; *Health Services Accessibility; Acute Disease; Stroke/*therapy; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, B4CKSYAV,journalArticle,2006,"McEwan, Phil; Peters, John R.; Bergenheim, Klas; Currie, Craig J.",Evaluation of the costs and outcomes from changes in risk factors in type 2 diabetes using the Cardiff stochastic simulation cost-utility model (DiabForecaster).,Current medical research and opinion,,0300-7995 0300-7995,10.1185/030079906X80350,,"AIMS: The aim of this study was to determine the mean costs and outcomes associated with modifiable risk factors in patients with type 2 diabetes and to determine equivalent changes to these risk factors in terms of financial costs and health outcomes. METHODS: The Cardiff Stochastic Simulation Cost-Utility Model (DiabForecaster), which evolved from the Eastman model, was used to follow a cohort of 10 000 patients over 20 years. RESULTS: Costs were affected most significantly by changes in the total cholesterol to HDL cholesterol (Total-C:HDL-C) ratio and in HbA(1c). Unit increases in Total-C:HDL-C increased discounted costs by pound 200 per patient; for ratios > 8 units, unit increases led to cost increases of pound 300 per patient. Unit increases in HbA(1c) increased per patient discounted costs from pound 200 (5-6%) up to pound 2900 (10-11%). Similar patterns were observed for QALYs. Estimates of equivalence showed that a 1% reduction in HbA(1c) was equivalent to an 0.4 increment in QALYs, which was equivalent to a reduction of 44 mmHg in SBP, 18.2 mg/dL in HDL, 100 mg/dL in total cholesterol or 1.8 units of Total-C:HDL-C ratio. A 1% reduction in HbA(1c) was also equivalent to pound 108 less cost, which was equivalent to a 13.0 mmHg decrease in SBP or a 0.57 unit decrease in the Total-C:HDL-C ratio. CONCLUSIONS: This model provides reliable utility estimates for diabetic complications and may eliminate uncertainty in cost-effectiveness analyses of treatment. These data also provide a novel way of comparing the value of treatments that have multiple effects.",2006-01,26/11/2018 12:53,14/04/2020 08:34,,121-129,,1,22,,Curr Med Res Opin,,,,,,,,eng,,,,,,,PMID: 16393438,,,,"Humans; Treatment Outcome; Adult; Female; Male; Middle Aged; Risk Factors; *Models, Economic; Aged; Prognosis; Aged, 80 and over; *Health Care Costs; discrete event simulation; Stochastic Processes; 1; Diabetes Mellitus, Type 2/*economics/epidemiology/*therapy; Stochastic simulation; 410",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HBVJH5F6,journalArticle,2006,"Chase, D.; Roderick, P.; Cooper, K.; Davies, R.; Quinn, T.; Raftery, J.",Using simulation to estimate the cost effectiveness of improving ambulance and thrombolysis response times after myocardial infarction.,Emergency medicine journal : EMJ,,1472-0213 1472-0205,,,"OBJECTIVES: To quantify the health gains and costs associated with improving ambulance and thrombolysis response times for acute myocardial infarction. DESIGN: A computer simulation model. PATIENTS/SETTINGS: Patients experiencing acute myocardial infarction in England. INTERVENTIONS: Improving the ambulance response time to 75% of calls reached within 8 minutes and the hospital arrival to thrombolysis time interval (door-to-needle time) to 75% receiving it within 30 minutes and 20 minutes, compared to best estimates of response times in the mid-1990s. MAIN OUTCOME MEASURES: Deaths prevented, life years saved, and discounted cost per life year saved. RESULTS: Improving the ambulance response to 75% of calls within 8 minutes resulted in an estimate of 5 deaths prevented or 57 life years saved per million population per year, with a discounted incremental cost per life year saved of 8540 pounds sterling over 20 years. The corresponding benefit of improving the door-to-needle time to 75% of myocardial infarction patients within 30 minutes was an estimated 2 deaths prevented and 15 life years saved per million population per year, with a discounted incremental cost per life year saved of between 10,150 pounds sterling to 54,230 pounds sterling over 20 years. Little further gain was associated with reaching the 20 minute target. Combining ambulance and thrombolysis targets resulted in 70 life years saved per million population per year. CONCLUSIONS: Improving ambulance response times appears to be cost effective. Reducing door-to-needle time will have a smaller effect at an uncertain cost. Further benefits may be gained from reducing the time from onset of symptoms to starting thrombolysis.",2006-01,26/11/2018 12:53,14/04/2020 08:34,,67-72,,1,23,,Emerg Med J,,,,,,,,eng,,,,,,,PMID: 16381082 PMCID: PMC2564138,,,,"Humans; Health Services Research; Cost-Benefit Analysis; Aged; Health Care Costs/statistics & numerical data; *Computer Simulation; Aged, 80 and over; Time Factors; England; *Models, Econometric; Ambulances/*economics/standards; Myocardial Infarction/drug therapy/*economics; Thrombolytic Therapy/*economics/standards; 00; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, W8VKXC9C,journalArticle,2005,"Zhou, Honghong; Isaman, Deanna J. M.; Messinger, Shari; Brown, Morton B.; Klein, Ronald; Brandle, Michael; Herman, William H.","A computer simulation model of diabetes progression, quality of life, and cost.",Diabetes care,,0149-5992 0149-5992,,,"OBJECTIVE: To develop and validate a comprehensive computer simulation model to assess the impact of screening, prevention, and treatment strategies on type 2 diabetes and its complications, comorbidities, quality of life, and cost. RESEARCH DESIGN AND METHODS: The incidence of type 2 diabetes and its complications and comorbidities were derived from population-based epidemiologic studies and randomized, controlled clinical trials. Health utility scores were derived for patients with type 2 diabetes using the Quality of Well Being-Self-Administered. Direct medical costs were derived for managed care patients with type 2 diabetes using paid insurance claims. Monte Carlo techniques were used to implement a semi-Markov model. Performance of the model was assessed using baseline and 4- and 10-year follow-up data from the older-onset diabetic population studied in the Wisconsin Epidemiologic Study of Diabetic Retinopathy (WESDR). RESULTS: Applying the model to the baseline WESDR population with type 2 diabetes, we predicted mortality to be 51% at 10 years. The prevalences of stroke and myocardial infarction were predicted to be 18 and 19% at 10 years. The prevalences of nonproliferative diabetic retinopathy, proliferative retinopathy, and macular edema were predicted to be 45, 16, and 18%, respectively; the prevalences of microalbuminuria, proteinuria, and end-stage renal disease were predicted to be 19, 39, and 3%, respectively; and the prevalences of clinical neuropathy and amputation were predicted to be 52 and 5%, respectively, at 10 years. Over 10 years, average undiscounted total direct medical costs were estimated to be USD $53,000 per person. Among survivors, the average utility score was estimated to be 0.56 at 10 years. CONCLUSIONS: Our computer simulation model accurately predicted survival and the cardiovascular, microvascular, and neuropathic complications observed in the WESDR cohort with type 2 diabetes over 10 years. The model can be used to predict the progression of diabetes and its complications, comorbidities, quality of life, and cost and to assess the relative effectiveness, cost-effectiveness, and cost-utility of alternative strategies for the prevention and treatment of type 2 diabetes.",2005-12,26/11/2018 12:53,14/04/2020 08:34,,2856-2863,,12,28,,Diabetes Care,,,,,,,,eng,,,,,,,PMID: 16306545,,,,"Humans; Female; Male; Computer Simulation; Costs and Cost Analysis; Disease Progression; Models, Biological; Continental Population Groups; Diabetes Complications/economics/physiopathology/psychology; Diabetes Mellitus/*economics/*physiopathology/*psychology; Michigan; Wisconsin; 1; Human; Models; Biological; Funding Source; Diabetes Mellitus – Economics; Diabetes Mellitus – Physiopathology; 210; Asses needs and goals",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WHZK2E2L,journalArticle,2005,"Chanut, C.; Boyer, L.; Robitail, S.; Horte, C.; Jacqueme, B.; Giusiano, B.; Mabriez, J. C.; Auquier, P.",[Applying social network analysis to the health system].,"Sante publique (Vandoeuvre-les-Nancy, France)",,0995-3914 0995-3914,,,"BACKGROUND: Social network analysis is a method for describing and contextualising the structural relationships amongst social entities. The aim of this study was to assess the relationships between hospitals through the use of an example of a hospital that takes care of myocardial infarction in the region of Provence Alpes Cote d'Azur (PACA). METHOD: This retrospective study included all patients hospitalised for acute coronary syndrome in the PACA region between January and June 2000. The description analysis consisted of making a graph describing the transfer of patients between hospitals to calculate indicators for the centrality of the hospital and its prestige. The graph was also used to determine and measure the sub-group cohesion (cliques) and the density of the hospital network. RESULTS: A total of 2049 patients suffering from myocardial infarction were admitted to 78 hospitals during the study period. There were 867 transfers from one hospital to another. 51 cliques were highlighted; 29 hospitals do not belong to a clique. Among the 49 hospitals who do belong to sub-groups, 50% are linked to two cliques. Eight hospitals belong to more than 8 sub-groups, and the maximum number of sub-groups to which a hospital is linked is 12. The density of the hospital network is 0.12. CONCLUSIONS: Social network analysis is a field of research open and adaptable to the public health scene. This method could be applied to the evaluation of health and hospital administration and management networks.",2005-09,26/11/2018 12:53,14/04/2020 08:34,,403-415,,3,17,,Sante Publique,,,,,,,,fre,,,,,,,PMID: 16285422,,,,France; Humans; Hospital Administration; *Community Networks; 1; *Patient Transfer; Delivery of Health Care/organization & administration; Myocardial Infarction/*therapy; Social Network Analysis; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MEFGIDZC,journalArticle,2005,"Ahmad, Sajjad; Billimek, John",Estimating the health impacts of tobacco harm reduction policies: a simulation modeling approach.,Risk analysis : an official publication of the Society for Risk Analysis,,0272-4332 0272-4332,10.1111/j.1539-6924.2005.00647.x,,"With adult smoking prevalence rates declining too slowly to reach national objectives, opinion leaders are considering policies to improve tobacco-related outcomes by regulating the composition of cigarettes to be (1) less harmful and/or (2) less addictive. Because harm reduction efforts may actually encourage higher cigarette consumption by promoting a safer image, and addictiveness reduction may increase the harmfulness of cigarettes by encouraging compensatory smoking behaviors, policymakers must consider the tradeoffs between these two approaches when proposing legislation to control cigarette content. To estimate health impacts, we developed a dynamic computer model simulating changes in the age- and gender-specific smoking behaviors of the U.S. population over time. Secondary data for model parameters were obtained from publicly available sources. Population health impacts were measured as change in smoking prevalence and the change in cumulative quality-adjusted life-years (QALYs) in the U.S. population over 75 years. According to the risk-use threshold matrix generated by the simulation, modifying cigarettes to reduce their harmfulness and/or addictiveness could result in important gains to the nation's health. Addictiveness reduction efforts producing a 60% improvement in smoking behavior change probabilities would produce a net gain in population health at every plausible level of increase of smoking-related harm that was modeled. A 40% reduction in smoking-related harm would produce a net QALY gain at every level of behavior change considered. This research should prove useful to policymakers as they contemplate giving the FDA the authority to regulate the composition of cigarettes.",2005-08,26/11/2018 12:53,14/04/2020 08:34,,801-812,,4,25,,Risk Anal,,,,,,,,eng,,,,,,,PMID: 16268930,,,,"Humans; Adult; United States/epidemiology; Models, Statistical; discrete event simulation; Life Tables; Risk-Taking; 1; *Smoking Prevention; Smoking Cessation/methods/statistics & numerical data; Smoking/adverse effects/legislation & jurisprudence/mortality; Tobacco/*toxicity; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PLIYIW4D,journalArticle,2005,"Taylor, Kathryn; Dangerfield, Brian; Le Grand, Julian",Simulation analysis of the consequences of shifting the balance of health care: a system dynamics approach.,Journal of health services research & policy,,1355-8196 1355-8196,10.1258/135581905774414169,,"OBJECTIVES: The shift in the balance of health care, bringing services 'closer to home', is a well-established trend. This study sought to provide insight into the consequences of this trend, in particular the stimulation of demand, by exploring the underlying feedback structure. METHODS: We constructed a simulation model using the system dynamics method, which is specifically designed for the analysis of feedback structure. The model was calibrated to two cases of the shift in cardiac catheterization services in the UK. Data sources included archival data, observations and interviews with senior health care professionals. Key model outputs were the basic trends displayed by waiting lists, average waiting times, cumulative patient referrals, cumulative patient activity and cumulative overall costs. RESULTS: Demand was stimulated in both cases via several different mechanisms. We revealed the roles for clinical guidelines and capacity changes, and the typical responses to imbalances between supply and demand. Our analysis also demonstrated the potential benefits of changing the goals that drive activity by seeking a waiting list goal rather than a waiting time goal. CONCLUSIONS: Appreciating the wider consequences of shifting the balance of care is essential if services are to be improved overall. The underlying feedback mechanisms of both intended and unintended effects need to be understood. Using a systemic approach, more effective policies may be designed through coordinated programmes rather than isolated initiatives, which may have only a limited impact.",2005-10,26/11/2018 12:53,14/04/2020 08:34,,196-202,,4,10,,J Health Serv Res Policy,,,,,,,,eng,,,,,,,PMID: 16259685,,,,"*Health Care Reform; Humans; United Kingdom; System dynamics; Models, Organizational; State Medicine/*organization & administration; Cardiac Catheterization; 1; *Health Services Needs and Demand; Home Care Services; Medical Audit; 310",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FTC8HPUC,journalArticle,2005,"Finkelstein, Eric A.; Brown, Derek S.",A cost-benefit simulation model of coverage for bariatric surgery among full-time employees.,The American journal of managed care,,1088-0224 1088-0224,,,OBJECTIVE: To use a simulation model to estimate the costs and benefits of bariatric surgery among full-time employees. STUDY DESIGN: Multivariate regression analysis of nationally representative survey data sets to estimate the costs of obesity and a simulation model of the number of years until breakeven under alternate assumptions about the costs and benefits of bariatric surgery. METHODS: We used a 2-part model to estimate medical costs of obesity based on the,2005-10,26/11/2018 12:53,14/04/2020 08:34,,641-646,,10,11,,Am J Manag Care,,,,,,,,eng,,,,,,,PMID: 16232005,,,,"Humans; United States; Adult; Female; Male; Middle Aged; Adolescent; Regression Analysis; Cost-Benefit Analysis/*methods; *Models, Econometric; 1; Multivariate Analysis; *Insurance Coverage; *Health Benefit Plans, Employee; Bariatric Surgery/*economics; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WVB2HG66,journalArticle,2005,"Newman, Diana M. L.",A community nursing center for the health promotion of senior citizens based on the Neuman systems model.,Nursing education perspectives,,1536-5026 1536-5026,,,"This article describes a community nursing center that provided clinical learning experiences for students from two schools of nursing. Work at the center was based on the Neuman systems model, which views the client as a system in interaction with environmental stressors. Nursing interventions focused on health promotion services for an underserved elderly population. The benefits of using the Neuman systems model for patient care, education, and research are outlined.",2005-08,26/11/2018 12:53,14/04/2020 08:35,,221-223,,4,26,,Nurs Educ Perspect,,,,,,,,eng,,,,,,,PMID: 16175912,,,,"Humans; Program Evaluation; Clinical Competence; Education, Nursing, Baccalaureate/*organization & administration; Nursing Evaluation Research; Aged; Systems Theory; Health Promotion/*organization & administration; Pennsylvania; Social Support; Frail Elderly; Interinstitutional Relations; 00; Holistic Health; Medically Underserved Area; Needs Assessment/organization & administration; *Community Health Nursing/education/organization & administration; *Geriatric Nursing/education/organization & administration; Community Health Centers/*organization & administration; Forms and Records Control; Models, Nursing; Nursing Records; Philosophy, Nursing; Vulnerable Populations; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, H6ZULPDV,journalArticle,2005,"Idvall, Ewa; Brudin, Lars",Do health care professionals underestimate severe pain more often than mild pain? Statistical pitfalls using a data simulation model.,Journal of evaluation in clinical practice,,1356-1294 1356-1294,10.1111/j.1365-2753.2005.00554.x,,"RATIONALE: When comparing patients' pain ratings with the health care professional's conception of pain assessed by Visual Analogue Scales (VAS) ratings, statistical problems arise. METHOD AND RESULT: In this data simulation study we have shown that the tendency for health care professionals to underestimate severe pain compared with mild pain is probably not attributed to difficulties in judging severe pain more often than mild but the result of professionals having a different and often narrower distribution of their ratings compared with patients.",2005-10,26/11/2018 12:53,14/04/2020 08:34,,438-443,,5,11,,J Eval Clin Pract,,,,,,,,eng,,,,,,,PMID: 16164584,,,,"Humans; Models, Theoretical; Patients/*psychology; 00; *Pain Measurement; Health Personnel/*psychology; Pain/*classification; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, K92F96ZU,journalArticle,2005,"Lemmetty, Kaisa; Hayrinen, Eija",Operation management system evaluation in the central Finland health care district - end users' view of system implementation.,Studies in health technology and informatics,,0926-9630 0926-9630,,,"In this paper we evaluate the implementation of the operation management system in the Central Finland Health Care District. The implementation of the operation management system changed the practice of operation management for the surgical clinic and concerned 500 personnel in total. A survey was carried out to investigate the end users' views on the system's usefulness, usability and the training and user support provided. The users' possibilities to accomplish their tasks and the kind of obstacles they face in operation management were explored. The assessment revealed that more end support is needed after the system implementation, even though a generally positive attitude towards the system was manifested among the staff.",2005,26/11/2018 12:53,14/04/2020 08:34,,605-607,,,116,,Stud Health Technol Inform,,,,,,,,eng,,,,,,,PMID: 16160324,,,,Humans; *Delivery of Health Care; Finland; Attitude of Health Personnel; *Surveys and Questionnaires; 1; Health Services; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, SQJUYSG4,journalArticle,2005,"Young, Terry",An agenda for healthcare and information simulation.,Health care management science,,1386-9620 1386-9620,,,"With healthcare systems around the world undergoing redesign and refocusing on patients, there is a strategic role that simulation modellers could play. The creation of strategic scenarios that work according to process philosophies--as used, for instance, in manufacturing--could help to deliver high quality care to millions of people. There may, in addition, be serendipitous synergies between some of these industrial process philosophies and known simulation techniques. This paper addresses some strategic issues around the processes of care delivery, and considers the resultant research agenda. Not only is this strategic agenda one that would help care providers, but it is possible to derive some concepts that enable technology to be valued as part of care provision. The paper explores how, in general terms, value propositions may be derived that are acceptable to commissioning agencies and accessible to technology vendors. Were it possible to formalise these, they would be of significant benefit both to healthcare service providers and to their suppliers.",2005-08,26/11/2018 12:53,14/04/2020 08:35,,189-196,,3,8,,Health Care Manag Sci,,,,,,,,eng,,,,,,,PMID: 16134431,,,,Humans; Outcome and Process Assessment (Health Care); *Continuity of Patient Care; *Computer Simulation; Systems Analysis; United Kingdom; *Organizational Innovation; Health Services Needs and Demand; Organizational Objectives; Planning Techniques; Decision Theory; 1; *Total Quality Management; State Medicine/*organization & administration/standards; ******To read; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BZTWCWUF,journalArticle,2005,"Goldenberg, Dolly; Andrusyszyn, Mary-Anne; Iwasiw, Carroll",The effect of classroom simulation on nursing students' self-efficacy related to health teaching.,The Journal of nursing education,,0148-4834 0148-4834,,,"The purpose of this descriptive study was to investigate the effect of classroom simulation on third-year baccalaureate nursing students' self-efficacy in health teaching. Bandura's self-efficacy model provided the conceptual framework. A nonprobability, convenience sample of 22 students completed the self-efficacy questionnaire before and after the simulation workshop sessions. Students' overall self-efficacy scores increased significantly (p = 0.001) following the two sessions of role-playing case studies, suggesting more perceived confidence in performing health teaching. Recommendations include continuing the use of simulation as a teaching-learning method, applying simulation as a strategy to enhance other learner behaviors, and cultivating faculty's use of simulation in their teaching.",2005-07,26/11/2018 12:53,14/04/2020 08:34,,310-314,,7,44,,J Nurs Educ,,,,,,,,eng,,,,,,,PMID: 16094789,,,,"Humans; Ontario; Surveys and Questionnaires; Adult; Female; Nursing Education Research; *Patient Simulation; Students, Nursing/*psychology; Interprofessional Relations; Decision Making; *Self Efficacy; *Attitude of Health Personnel; Education, Nursing, Baccalaureate/*methods; Models, Educational; Role Playing; 00; Clinical Competence/*standards; Models, Nursing; Models, Psychological; Patient Education as Topic/*standards; Teaching/standards; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, EC4YA2JR,journalArticle,2005,"Singh, Ranjit; Singh, Ashok; Fox, Chester; Seldan Taylor, John; Rosenthal, Thomas; Singh, Gurdev",Computer visualisation of patient safety in primary care: a systems approach adapted from management science and engineering.,Informatics in primary care,,1476-0320 1475-9985,,,"Patient safety and medical errors in ambulatory primary care are receiving increasing attention from policy makers, accreditation bodies and researchers, as well as by practising family physicians and their patients. While a great deal of progress has been made in understanding errors in hospital settings, it is important to recognise that ambulatory settings pose a very large and different set of challenges and that the types of hazards that exist and the strategies required to reduce them are very different. What is needed is a logical theoretical model for understanding the causes of errors in primary care, the role of healthcare systems in contributing to errors, the propagation of errors through complex systems and, importantly, for understanding ambulatory primary care in the context of the larger healthcare system. The authors have developed such a model using a formal 'systems engineering' approach borrowed from the management sciences and engineering. This approach has not previously been formally described in the medical literature.This paper outlines the formal systems approach, presents our visual model of the system, and describes some experiences with and potential applications of the model for monitoring and improving safety. Applications include providing a framework to help focus research efforts, creation of new (visual) error reporting and taxonomy systems, furnishing a common and unambiguous vision for the healthcare team, and facilitating retrospective and prospective analyses of errors and adverse events. It is aimed at system redesign for safety improvement through a computer-based patient-centred safety enhancement and monitoring instrument (SEMI-P). This model can be integrated with electronic medical records (EMRs).",2005,20/11/2018 14:35,14/04/2020 08:39,,135-144,,2,13,,Inform Prim Care,,,,,,,,eng,,,,,,,PMID: 15992498,,,,"Humans; Patient Safety; Models, Theoretical; Quality Improvement; Ambulatory Care; Process Assessment (Health Care); *Safety Management; Medical Errors/*prevention & control; Systems Theory; Primary Health Care/*organization & administration; Total Quality Management; 1; Models; Theoretical; Medication Errors – Prevention and Control; Computers and Computerization; Consumer Participation; Human Error – Prevention and Control; Outpatients; Primary Health Care – Administration; Reminder Systems; Artificial Intelligence; Medical Records Systems, Computerized; *Computers; System Analysis; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9KU3EHHP,journalArticle,2005,"Mao, Qun-xia; Li, Xiao-song",[Markov Chain Monte Carlo Method of multiple imputation for longitudinal data with missing values in the survey of maternal and children health].,Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition,,1672-173X 1672-173X,,,"OBJECTIVE: To deal with arbitrary missing pattern in longitudinal data of the Survey of Maternal and Child Health and make the most appropriate inferences with multiple imputation (MI) for further analysis. METHODS: SAS 9.0 was used for Markov Chain Monte Carlo (MCMC) method of MI procedure to impute missing values and combine inferences. RESULTS: The result is acceptable as the data set was imputed 5 times. CONCLUSION: MI is able to solve a variety of problems in missing data sets and to improve the statistical power, especially with the use of MCMC method, for complicated missing data sets.",2005-05,26/11/2018 12:53,14/04/2020 08:34,,422-425,,3,36,,Sichuan Da Xue Xue Bao Yi Xue Ban,,,,,,,,chi,,,,,,,PMID: 15931886,,,,"Humans; Female; Male; China/epidemiology; Markov Chains; *Models, Statistical; Child; Monte Carlo Method; Research Design; Child, Preschool; Infant; Epidemiologic Methods; Longitudinal Studies; Bias; *Data Interpretation, Statistical; 00; *Infant Mortality; Child Mortality; Child Welfare/statistics & numerical data; Data Collection/methods/standards; Maternal-Child Health Centers/*statistics & numerical data; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BKTCPMGN,journalArticle,2005,"Tamang, S.; Kopec, D.; Shagas, G.; Levy, K.",Improving end of life care: an information systems approach to reducing medical errors.,Studies in health technology and informatics,,0926-9630 0926-9630,,,"Chronic and terminally ill patients are disproportionately affected by medical errors. In addition, the elderly suffer more preventable adverse events than younger patients. Targeting system wide ""error-reducing"" reforms to vulnerable populations can significantly reduce the incidence and prevalence of human error in medical practice. Recent developments in health informatics, particularly the application of artificial intelligence (AI) techniques such as data mining, neural networks, and case-based reasoning (CBR), presents tremendous opportunities for mitigating error in disease diagnosis and patient management. Additionally, the ubiquity of the Internet creates the possibility of an almost ideal network for the dissemination of medical information. We explore the capacity and limitations of web-based palliative information systems (IS) to transform the delivery of care, streamline processes and improve the efficiency and appropriateness of medical treatment. As a result, medical error(s) that occur with patients dealing with severe, chronic illness and the frail elderly can be reduced.The palliative model grew out of the need for pain relief and comfort measures for patients diagnosed with cancer. Applied definitions of palliative care extend this convention, but there is no widely accepted definition. This research will discuss the development life cycle of two palliative information systems: the CONFER QOLP management information system (MIS), currently used by a community-based palliative care program in Brooklyn, New York, and the CAREN case-based reasoning prototype. CONFER is a web platform based on the idea of ""eCare"". CONFER uses XML (extensible mark-up language), a",2005,26/11/2018 12:53,14/04/2020 08:35,,93-104,,,114,,Stud Health Technol Inform,,,,,,,,eng,,,,,,,PMID: 15923765,,,,Humans; Systems Analysis; Medical Errors; 00; Palliative Care; Artificial Intelligence; *Hospice Care; *Terminal Care; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, QSQLPZBC,journalArticle,2005,"Ahmad, Sajjad",Increasing excise taxes on cigarettes in California: a dynamic simulation of health and economic impacts.,Preventive medicine,,0091-7435 0091-7435,10.1016/j.ypmed.2004.10.024,,"BACKGROUND: California raised cigarette excise taxes in 1999, and may generate additional health and economic benefits by raising them further. METHODS: A dynamic computer simulation model follows births, deaths, migration, aging, and changes in smoking status for the entire population of California over 75 years to estimate the cumulative health and economic outcomes of these changes under several excise tax rate conditions (up to 100% price increase). RESULTS: A 20% tax-induced cigarette price increase would reduce smoking prevalence from 17% to 11.6% with large gains in cumulative life years (14 million) and QALY's (16 million) over 75 years. Total spending on cigarettes by consumers would increase by 270 million dollars in that span (all going to tax revenue), and those who reduce the number of years spent as a smoker would spend 12.5 billion dollars less on cigarettes. Total smoking-related medical costs would drop by 188 billion dollars. These benefits increase greatly with larger tax increases, with which tax revenues continue to rise even as smoking prevalence falls. CONCLUSIONS: Even considering benefits from the 1999 increase, California has not yet maximized the potential of excise taxes to lessen the negative impacts of smoking. Additional tax increases would provide added health benefits and revenue to the state.",2005-07,26/11/2018 12:53,14/04/2020 08:34,,276-283,,1,41,,Prev Med,,,,,,,,eng,,,,,,,PMID: 15917022,,,,"Humans; Quality-Adjusted Life Years; Female; Male; *Health Care Costs; Policy Making; System dynamics; Health Promotion/methods; Models, Economic; Sensitivity and Specificity; Health Status; Smoking Prevention; Smoking/*economics; California; Predictive Value of Tests; 1; Taxes/*legislation & jurisprudence; Smoking Cessation/economics; Tobacco Industry/*economics/legislation & jurisprudence; 210",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 68ITR9JI,journalArticle,2005,"Shinnick, Thomas M.; Iademarco, Michael F.; Ridderhof, John C.",National plan for reliable tuberculosis laboratory services using a systems approach. Recommendations from CDC and the Association of Public Health Laboratories Task Force on Tuberculosis Laboratory Services.,MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports,,1545-8601 1057-5987,,,"Since the mid-1990s, public health laboratories have improved tuberculosis (TB) test performance, which has contributed to the resumption of the decline in TB incidence in the United States. However, to eliminate TB in the United States, further improvements are needed in laboratory services to support TB treatment, prevention, and control. A critical step is the development of an integrated system that ensures prompt and reliable laboratory testing and flow of information among laboratorians, clinicians, and TB-control officials. Challenges to developing such a system include 1) establishing lines of communication among laboratorians, clinicians, and TB-control officials; 2) expediting reporting of laboratory results, which can avoid delayed or inappropriate treatment and missed opportunities to prevent transmission; 3) developing evidence-based recommendations for use of new laboratory technologies; 4) maintaining staff proficiency in light of declining numbers of specimens to test, workforce shortages, and loss of laboratory expertise; and 5) upgrading laboratory information systems and connecting all partners. The report of the Association of Public Health Laboratories Task Force presents a framework to improve the future of TB laboratory services and describes the role of the laboratory in TB treatment and control, Task Force processes, general principles and benchmarks, and steps for the dissemination of the Task Force recommendations. This MMWR expands on the Task Force report by describing specific actions and performance measures to guide development and implementation of an integrated system for providing TB laboratory services. CDC and the Association of Public Health Laboratories have developed these guidelines so that laboratorians, clinicians, public health officials, administrators, and funding entities can work together to ensure that health-care providers and TB-control officials have the information needed to treat TB patients, prevent TB transmission, and ultimately eliminate TB in the United States.",15/04/2005,26/11/2018 12:53,14/04/2020 08:35,,01-Dec,,RR-6,54,,MMWR Recomm Rep,,,,,,,,eng,,,,,,,PMID: 15829862,,,,Humans; United States; Laboratories; Program Development; Centers for Disease Control and Prevention (U.S.); Program Implementation; Health Care Delivery; Practice Guidelines; Diagnosis; Integrated; Laboratory; Tuberculosis – Diagnosis; 00; Public Health Informatics; Clinical Laboratory Techniques; Neural Networks (Computer); *Clinical Laboratory Information Systems; Computer Communication Networks; Laboratories/*standards; Tuberculosis/*prevention & control; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ZK7YHJGK,journalArticle,2005,"Gregory, Jane; Gibson, Barry; Robinson, Peter G.",Variation and change in the meaning of oral health related quality of life: a 'grounded' systems approach.,Social science & medicine (1982),,0277-9536 0277-9536,10.1016/j.socscimed.2004.08.039,,"Changes in concepts of health and disease have led to increased interest in health related quality of life in medicine. Quality of life measures tend to treat quality of life as a stable construct that can be measured externally. They do not consider people's differing expectations and assume that what quality of life means to people is stable over time. This paper reports on a study which aimed to find out how measures of oral health related quality of life (OHRQoL) vary between and change within individuals. Longitudinal semi-structured open-ended interviews were carried out with twenty people with socially noticeable broken, decayed or missing teeth who were or were not seeking dental treatment. The data were collected and analysed using the iterative processes of grounded systems theory based on Glaserian (Theoretical Sensitivity, The Sociology Press, Mill Valley, CA, 1978) grounded theory and Luhmann's (Social Systems, Stanford University, Stanford, 1984) social systems theory. During the data analysis it emerged that participants' were adopting positions on seven dimensions of oral health relating to the positions that people would adopt with respect norm, attribution, trust, accessibility, commodity, authenticity, and character. The core distinction that accommodated people's varying positions was that people constructed their own margins of relevance of oral health. The margins of relevance indicated a variable from a hypothetical extreme of 'super-relevant' to the other extreme of 'not relevant'. The margins of relevance could shift, meaning that assessments of quality of life would vary. Oral health related quality of life is therefore defined as the cyclical and self-renewing interaction between the relevance and impact of oral health in everyday life.",2005-04,26/11/2018 12:53,14/04/2020 08:34,,1859-1868,,8,60,,Soc Sci Med,,,,,,,,eng,,,,,,,PMID: 15686816,,,,Humans; Health Services Accessibility; Adult; Female; Male; Middle Aged; Reproducibility of Results; Aged; Grounded Theory; Quality of Life; Time Factors; *Quality of Life; Longitudinal Studies; Social Class; Systems Theory; Human; Semi-Structured Interview; Dental Care – Economics; Dental Care – Psychosocial Factors; Oral Health – Psychosocial Factors; Purposive Sample; Self Concept; 00; *Oral Health; Dental Care/economics/psychology; Tooth Loss/economics/psychology; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, SGS6SSDV,journalArticle,2005,"Voss, John D.; Nadkarni, Mohan M.; Schectman, Joel M.",The Clinical Health Economics System Simulation (CHESS): a teaching tool for systems- and practice-based learning.,Academic medicine : journal of the Association of American Medical Colleges,,1040-2446 1040-2446,,,"Academic medical centers face barriers to training physicians in systems- and practice-based learning competencies needed to function in the changing health care environment. To address these problems, at the University of Virginia School of Medicine the authors developed the Clinical Health Economics System Simulation (CHESS), a computerized team-based quasi-competitive simulator to teach the principles and practical application of health economics. CHESS simulates treatment costs to patients and society as well as physician reimbursement. It is scenario based with residents grouped into three teams, each team playing CHESS using differing (fee-for-service or capitated) reimbursement models. Teams view scenarios and select from two or three treatment options that are medically justifiable yet have different potential cost implications. CHESS displays physician reimbursement and patient and societal costs for each scenario as well as costs and income summarized across all scenarios extrapolated to a physician's entire patient panel. The learners are asked to explain these findings and may change treatment options and other variables such as panel size and case mix to conduct sensitivity analyses in real time. Evaluations completed in 2003 by 68 (94%) CHESS resident and faculty participants at 19 U.S. residency programs preferred CHESS to a traditional lecture-and-discussion format to learn about medical decision making, physician reimbursement, patient costs, and societal costs. Ninety-eight percent reported increased knowledge of health economics after viewing the simulation. CHESS demonstrates the potential of computer simulation to teach health economics and other key elements of practice- and systems-based competencies.",2005-02,26/11/2018 12:53,14/04/2020 08:35,,129-134,,2,80,,Acad Med,,,,,,,,eng,,,,,,,PMID: 15671315,,,,"Humans; United States; Health Care Costs; Adult; Female; Male; Academic Medical Centers; Decision Making; Models, Economic; *Computer-Assisted Instruction; 00; *Internship and Residency; *Education, Medical, Graduate; Faculty, Medical; Managed Care Programs/*organization & administration; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, PP3RZDG5,journalArticle,2005,"Puckett, Ruby P.; Connell, Bert C.; Dahl, Marilyn K.; Jackson, Rita; McClusky, Kathleen W.",Practice paper of the American Dietetic Association: A systems approach to measuring productivity in health care foodservice operations.,Journal of the American Dietetic Association,,0002-8223 0002-8223,10.1016/j.jada.2004.11.015,,,2005-01,26/11/2018 12:53,14/04/2020 08:35,,122-130,,1,105,,J Am Diet Assoc,,,,,,,,eng,,,,,,,PMID: 15635358,,,,"Humans; United States; *Systems Analysis; *Efficiency, Organizational; Professional Competence; Benchmarking; 00; Administrative Personnel/*standards; Allied Health Personnel/*standards; Dietetics; Food Service, Hospital/standards; Food Services/*standards; Health Facility Administrators; Societies; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VDAI6RAX,journalArticle,2004,"Cox, Louis Anthony Jr; Popken, Douglas A.",Bayesian Monte Carlo uncertainty analysis of human health risks from animal antimicrobial use in a dynamic model of emerging resistance.,Risk analysis : an official publication of the Society for Risk Analysis,,0272-4332 0272-4332,10.1111/j.0272-4332.2004.00516.x,,"Recent qualitative analyses warn of potential future human health risks from emergence of antibiotic resistance in food-borne pathogens due to the use of similar antimicrobial drugs in both food animals and human medicine. While historical data suggest that human health risks from some animal antimicrobials, such as virginiamycin (VM), have remained low (McDonald et al., 2001), there is a widespread concern that ""resistance epidemics"" or endemics could arise in the future. How reassuring is the past about the future? This article applies quantitative risk assessment methods to help find out, using human health risks from VM and the nearly identical human antimicrobial quinupristin-dalfopristin (QD) as a case study. A dynamic simulation model is used to predict the risks of emerging resistance to human antimicrobials in human populations from given input assumptions. Bayesian Monte Carlo uncertainty analysis allows past data to constrain and inform selection of input parameter values, and thus to predict the possible future resistance patterns that are consistent with historical data. The results show that health risks from VM use in food animals are highly sensitive to the human prescription rate of QD. For realistic prescription rates, quantitative risks are less than 1 x 10(-6) even for members of the most-threatened (ICU patient) population, while societal risks are <1 excess statistical death per year for the whole U.S. population. Such quantitative estimates complement more qualitative assessments that discuss the possibility of future ""resistance epidemics"" (or endemics) without quantifying their probabilities.",2004-10,26/11/2018 12:53,14/04/2020 08:34,,1153-1164,,5,24,,Risk Anal,,,,,,,,eng,,,,,,,PMID: 15563285,,,,"Humans; Risk Assessment; Monte Carlo Method; Bayes Theorem; Models, Statistical; Animals; Models, Biological; Stochastic Processes; Risk Management; Drug Resistance; *Food Microbiology; Anti-Bacterial Agents/*adverse effects; Virginiamycin/adverse effects; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, L9TA7D6B,journalArticle,2004,"Gaba, D. M.",The future vision of simulation in health care.,Quality & safety in health care,,1475-3898 1475-3898,10.1136/qhc.13.suppl_1.i2,,"Simulation is a technique-not a technology-to replace or amplify real experiences with guided experiences that evoke or replicate substantial aspects of the real world in a fully interactive manner. The diverse applications of simulation in health care can be categorised by 11 dimensions: aims and purposes of the simulation activity; unit of participation; experience level of participants; health care domain; professional discipline of participants; type of knowledge, skill, attitudes, or behaviours addressed; the simulated patient's age; technology applicable or required; site of simulation; extent of direct participation; and method of feedback used. Using simulation to improve safety will require full integration of its applications into the routine structures and practices of health care. The costs and benefits of simulation are difficult to determine, especially for the most challenging applications, where long term use may be required. Various driving forces and implementation mechanisms can be expected to propel simulation forward, including professional societies, liability insurers, health care payers, and ultimately the public. The future of simulation in health care depends on the commitment and ingenuity of the health care simulation community to see that improved patient safety using this tool becomes a reality.",2004-10,26/11/2018 12:53,14/04/2020 08:34,,i2-10,,,13 Suppl 1,,Qual Saf Health Care,,,,,,,,eng,,,,,,,PMID: 15465951 PMCID: PMC1765792,,,,"Humans; United States; Health Personnel/*education; Health Knowledge, Attitudes, Practice; Professional Competence; 00; Safety Management/organization & administration; Inservice Training/*organization & administration; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4ZBEMZ52,journalArticle,2004,"Hoffmann, Thomas; Brunner, Helmut",Model for simulation of HIV/AIDS and cost-effectiveness of preventing non-tuberculous mycobacterial (MAC)-disease.,The European journal of health economics : HEPAC : health economics in prevention and care,,1618-7598 1618-7598,10.1007/s10198-003-0211-4,,"Because most HIV-infected patients die of diseases caused by opportunistic pathogens, the prevention of these infections is an important clinical issue. Cost-containment in the healthcare system is a subject of high priority in public debate. Methods to determine cost-effectiveness of different therapeutic strategies are therefore needed to obtain valid data as the basis for decisions on cost reduction without a decrease in the quality of care. A disease state transition model based on a Markov process was developed to simulate the natural history of HIV infection and the acquired immunodeficiency syndrome (AIDS). Using this model survival time and treatment costs for every patient can be estimated and the results of alternative medications compared. We determined the cost-effectiveness (per life-year saved, LYS) of different strategies for prevention of Mycobacterium avium complex infections in AIDS patients whose treatment regimens include protease inhibitors. The cost-effectiveness ratios for treatment strategies vary from 13,510 euro to 46,152 euro per LYS without protease inhibitors and from 22,309 euro to 51,336 euro with protease inhibitors. When azithromycin, clarithromycin, and rifabutin were compared, azithromycin was the most cost-effective medication for preventing M. avium complex. The results were stable against a wide range of parameter variations concerning costs and incidence rates.",2004-06,26/11/2018 12:53,14/04/2020 08:34,,129-135,,2,5,,Eur J Health Econ,,,,,,,,eng,,,,,,,PMID: 15452749,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Health Care Costs; Models, Economic; Anti-Bacterial Agents/economics/therapeutic use; Drug Therapy, Combination; CD4 Lymphocyte Count; Acquired Immunodeficiency Syndrome/complications/*economics; Azithromycin/economics/therapeutic use; Clarithromycin/economics/therapeutic use; Mycobacterium avium-intracellulare Infection/etiology/*prevention & control; Protease Inhibitors/administration & dosage/therapeutic use; Rifabutin/economics/therapeutic use; 00; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RRQA6UBA,journalArticle,2004,"Stahl, James E.; Rattner, David; Wiklund, Richard; Lester, Jessica; Beinfeld, Molly; Gazelle, G. Scott",Reorganizing the system of care surrounding laparoscopic surgery: a cost-effectiveness analysis using discrete-event simulation.,Medical decision making : an international journal of the Society for Medical Decision Making,,0272-989X 0272-989X,10.1177/0272989X04268951,,"PURPOSE: To determine the cost-effectiveness of a proposed reorganization of surgical and anesthesia care to balance patient volume and safety. METHODS: Discrete-event simulation methods were used to compare current surgical practice with a new modular system in which patient care is handed off between 2 anesthesiologists. A health care system's perspective, using hospital and professional costs, was chosen for the cost-effectiveness analysis. Outcomes were patient throughput, flow time, wait time, and resource use. Sensitivity analyses were performed on staffing levels, mortality rates, process times, and scheduled patient volume. RESULTS: The new strategy was more effective (average 4.41 patients/d [median = 5] v. 4.29 [median = 4]) and had similar costs (average cost/ patient/d = 5327 dollars v. 5289 dollars) to the current strategy with an incremental cost-effectiveness of 318 dollars/additional patient treated/d. Surgical mortality rate must be >4% or hand-off delay >15 min before the new strategy is no longer more effective. CONCLUSION: The proposed system is more cost-effective relative to current practice over a wide range of mortality rates, hand-off times, and scheduled patient volumes.",2004-10,26/11/2018 12:53,14/04/2020 08:35,,461-471,,5,24,,Med Decis Making,,,,,,,,eng,,,,,,,PMID: 15358995,,,,"Humans; Outcome Assessment (Health Care); Cost-Benefit Analysis; Academic Medical Centers; Safety; Appointments and Schedules; Computer Simulation; Efficiency, Organizational; Boston; Organizational Innovation; Anesthesia Department, Hospital/*organization & administration; Cholecystectomy, Laparoscopic/adverse effects/*economics; Hospital Restructuring/*economics; Operating Rooms/*organization & administration; Recovery Room/*organization & administration; Surgery Department, Hospital/*organization & administration; 00; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 24BDXZII,journalArticle,2004,"Bryans, Alison N.","Examining health visiting expertise: combining simulation, interview and observation.",Journal of advanced nursing,,0309-2402 0309-2402,10.1111/j.1365-2648.2004.03150.x,,"BACKGROUND: Resource constraints and the drive towards evidence-based practice are currently prompting the review of health visiting services, which are a costly element of community health services in the United Kingdom. There is a shortage of evidence about effective domiciliary health visiting practice that can inform local and national decisions about developing and reforming this service. AIMS: This paper is based on a study which aimed to articulate the health visiting expertise involved in recognizing and responding to client need during home visits. The paper describes the innovative, multi-method approach used to articulate this expertise, and presents the rationale for this unusual approach. DISCUSSION: The study used the complementary methods of a 20-minute simulated visit to an actress-client, a postsimulation focused interview and subsequent observation of actual home visits with 15 study participants. Data-gathering took place between 2001 and 2002. The rationale, strengths and limitations of the methodology are discussed, and recommendations made for further development based on the work. CONCLUSIONS: The findings confirmed the utility of this unusual combination of methods, with their blend of control and naturalism, for articulating the knowledge and expertise which underpins assessment practice. Further research using a similar approach is recommended for the systematic examination of professional expertise in nursing and multi-disciplinary contexts.",2004-09,26/11/2018 12:53,14/04/2020 08:34,,623-630,,6,47,,J Adv Nurs,,,,,,,,eng,,,,,,,PMID: 15324431,,,,Humans; Reproducibility of Results; Research Design; United Kingdom; Patient Simulation; Nursing Assessment; 00; Clinical Competence/*standards; Community Health Nursing/*standards; Quality of Health Care/standards; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HCGPH2SH,journalArticle,2004,"Nuijten, Mark J. C.",Incorporation of statistical uncertainty in health economic modelling studies using second-order Monte Carlo simulations.,PharmacoEconomics,,1170-7690 1170-7690,10.2165/00019053-200422120-00001,,"Health economic modelling studies are of interest to many parties with different responsibilities and diverging interests. Therefore, it is obvious that recognising the relevance of statistical uncertainty and dealing with it appropriately are required to obtain unbiased results from health economic modelling studies, especially when those data are being used for reimbursement decisions. In this manuscript we explore the relevance of the incorporation of statistical uncertainty in a health economic model and identify various types of statistical uncertainty. The concepts were applied to a hypothetical Markov model for a hypothetical antiparkinsonian (AP) product. The method was based on the incorporation of probability distributions in the input variables using a second-order Monte Carlo simulation and the definition of minimum relevant differences for clinical and economic input variables and outcomes. Our paper shows that the outcomes of a health economic model might be severely biased when statistical uncertainty is not taken into account, which justifies the need for the incorporation of statistical uncertainty in a health economic model.",2004,26/11/2018 12:53,14/04/2020 08:35,,759-769,,12,22,,Pharmacoeconomics,,,,,,,,eng,,,,,,,PMID: 15294010,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; *Models, Economic; Cohort Studies; *Uncertainty; *Monte Carlo Method; Bias; Clinical Trials as Topic; Antiparkinson Agents/economics/therapeutic use; Economics, Pharmaceutical/*statistics & numerical data; Parkinson Disease/drug therapy/economics/epidemiology; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HAUWWHUD,journalArticle,2004,"Jones, Roy W.; McCrone, Paul; Guilhaume, Chantal",Cost effectiveness of memantine in Alzheimer's disease: an analysis based on a probabilistic Markov model from a UK perspective.,Drugs & aging,,1170-229X 1170-229X,10.2165/00002512-200421090-00005,,"BACKGROUND: Clinical trials with memantine, an uncompetitive moderate-affinity NMDA antagonist, have shown improved clinical outcomes, increased independence and a trend towards delayed institutionalisation in patients with moderately severe-to-severe Alzheimer's disease. In a randomised double-blind, placebo-controlled, 28-week study conducted in the US, reductions in resource utilisation and total healthcare costs were noted with memantine relative to placebo. While these findings suggest that, compared with placebo, memantine provides cost savings, further analyses may help to quantify potential economic gains over a longer treatment period. OBJECTIVE: To evaluate the cost effectiveness of memantine therapy compared with no pharmacological treatment in patients with moderately severe-to-severe Alzheimer's disease over a 2-year period. METHODS: A Markov model was constructed to simulate patient progression through a series of health states related to severity, dependency (determined by patient scores on the Alzheimer's Disease Cooperative Study-Activities of Daily Living [ADCS-ADL] inventory and residential status ('institutionalisation') with a time horizon of 2 years (each 6-month Markov cycle was repeated four times). Transition probabilities from one health state to another 6 months later were mainly derived from a 28-week, randomised, double-blind, placebo-controlled clinical trial. Inputs related to epidemiological and cost data were derived from a UK longitudinal epidemiological study, while data on quality-adjusted life-years (QALYs) were derived from a Danish longitudinal study. To ensure conservative estimates from the model, the base case analysis assumed drug effectiveness was limited to 12 months. Monte Carlo simulations were performed for each state parameter following definition of a priori distributions for the main variables of the model. Sensitivity analyses included worst case scenario in which memantine was effective for 6 months and one-way sensitivity analyses on key parameters. Finally, a subgroup analysis was performed to determine which patients were most likely to benefit from memantine. Informal care was not included in this model as the costs were considered from National Health Service and Personal Social Services perspective. RESULTS: The base case analysis found that, compared with no treatment, memantine was associated with lower costs and greater clinical effectiveness in terms of years of independence, years in the community and QALYs. Sensitivity analyses supported these findings. For each category of Alzheimer's disease patient examined, treatment with memantine was a cost-effective strategy. The greatest economic gain of memantine treatment was in independent patients with a Mini-Mental State Examination score of > or =10. CONCLUSION: This model suggests that memantine treatment is cost effective and provides cost savings compared with no pharmacological treatment. These benefits appear to result from prolonged patient independence and delayed institutionalisation for moderately severe and severe Alzheimer's disease patients on memantine compared with no pharmacological treatment.",2004,26/11/2018 12:53,14/04/2020 08:34,,607-620,,9,21,,Drugs Aging,,,,,,,,eng,,,,,,,PMID: 15260515,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Aged; Markov Chains; Aged, 80 and over; Monte Carlo Method; Alzheimer Disease/drug therapy/*economics; Memantine/*economics/therapeutic use; Excitatory Amino Acid Antagonists/*economics/therapeutic use; Psychiatric Status Rating Scales; 00; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MI5XR9K5,journalArticle,2004,"Lomperis, Ana Maria Turner",Teaching economics in the graduate health administration curriculum: a mini-case simulation approach.,The Journal of health administration education,,0735-6722 0735-6722,,,"Training in the discipline of economics has long been recognized as an important component of the curriculum in graduate health administration (GHA) education. Yet economics is a subject that is often considered hard to teach and difficult for students to learn. What is missing is a body of literature that identifies methods that are most appropriate for teaching economics to graduate students aspiring to be health care managers. Moreover, given the keen interest in developing competency-based curricula today, what is also needed is empirical evidence, which systematically links the key skills, knowledge, and abilities economics courses try to develop with the teaching approaches best suited to do so. This paper helps fill this gap in the literature by describing and evaluating the author's ""Top of the News"" (TOTN) mini-case simulation series piloted in her Health Care Economics course in the Master of Health Administration (MHA) curriculum at Saint Louis University during the spring semester of 2002. This approach combines elements of the case study and simulation methods used by others, but adds several innovations. Although the TOTN method was designed specifically for a course in health care economics, it is one that can be readily adapted for courses across the GHA curriculum. The article concludes that although the TOTN exercises proved to be fairly successful, GHA faculty and practitioners concerned about preparing today's students to meet tomorrow's health care leadership challenges need to not only identify effective teaching methods, but also have a lot more to discover about the learning styles of the students they teach.",2004,26/11/2018 12:53,14/04/2020 08:34,,39-68,,1,21,,J Health Adm Educ,,,,,,,,eng,,,,,,,PMID: 15129899,,,,"Humans; Organizational Case Studies; Missouri; Teaching/*methods; Quality Assurance, Health Care; Professional Competence; *Problem-Based Learning; Feedback; 00; Education, Graduate/*methods; Health Services Administration/*economics; Hospital Administration/economics/*education; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MME7RVJJ,journalArticle,2004,"Provan, Keith G.; Veazie, Mark A.; Teufel-Shone, Nicolette I.; Huddleston, Carol",Network analysis as a tool for assessing and building community capacity for provision of chronic disease services.,Health promotion practice,,1524-8399 1524-8399,10.1177/1524839903259303,,"A network analysis was conducted in spring 2000 by the Southwest Center for Health Promotion in the U.S.-Mexico border community of Douglas, Arizona. The purpose of the analysis was to assess the level of collaboration among the 23 public and not-for-profit agencies that provided health and human services for a broad range of chronic disease prevention, screening, and treatment services. Data were also collected on levels of trust and anticipated outcomes (benefits and draw-backs) of collaboration. The article presents the findings of the network analysis, focusing on its usefulness as a tool for evaluating efforts at building community capacity through enhanced interagency collaboration.",2004-04,26/11/2018 12:53,14/04/2020 08:35,,174-181,,2,5,,Health Promot Pract,,,,,,,,eng,,,,,,,PMID: 15090171,,,,Humans; Community Health Planning; Arizona; Cooperative Behavior; *Health Promotion; 00; Chronic Disease/*therapy; Program Evaluation/methods; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GCNYFJDQ,journalArticle,2004,"Stevenson, M. D.; Oakley, J.; Chilcott, J. B.",Gaussian process modeling in conjunction with individual patient simulation modeling: a case study describing the calculation of cost-effectiveness ratios for the treatment of established osteoporosis.,Medical decision making : an international journal of the Society for Medical Decision Making,,0272-989X 0272-989X,10.1177/0272989X03261561,,"Individual patient-level models can simulate more complex disease processes than cohort-based approaches. However, large numbers of patients need to be simulated to reduce 1st-order uncertainty, increasing the computational time required and often resulting in the inability to perform extensive sensitivity analyses. A solution, employing Gaussian process techniques, is presented using a case study, evaluating the cost-effectiveness of a sample of treatments for established osteoporosis. The Gaussian process model accurately formulated a statistical relationship between the inputs to the individual patient model and its outputs. This model reduced the time required for future runs from 150 min to virtually-instantaneous, allowing probabilistic sensitivity analyses-to be undertaken. This reduction in computational time was achieved with minimal loss in accuracy. The authors believe that this case study demonstrates the value of this technique in handling 1st- and 2nd-order uncertainty in the context of health economic modeling, particularly when more widely used techniques are computationally expensive or are unable to accurately model patient histories.",2004-02,26/11/2018 12:53,14/04/2020 08:35,,89-100,,1,24,,Med Decis Making,,,,,,,,eng,,,,,,,PMID: 15005958,,,,"Humans; Cost-Benefit Analysis; *Quality-Adjusted Life Years; Computer Simulation; Health Care Costs/*statistics & numerical data; Uncertainty; *Decision Support Techniques; Models, Econometric; *Cost of Illness; *Normal Distribution; Alendronate/therapeutic use; Calcium/therapeutic use; Hip Fractures/economics/etiology; Hormone Replacement Therapy/economics; Osteoporosis/complications/*economics/*therapy; 1; Gaussian process model; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, P7TUBG9V,journalArticle,2002,"Sapula, Rafal A.",[The use of operation research tools as a way of more effective utilization of the resources of health service institutions].,"Wiadomosci lekarskie (Warsaw, Poland : 1960)",,0043-5147 0043-5147,,,"In all aspects of human life including medical we can find planning, organizing and controlling of activity. We aim at the proper goal supported by our resources and knowledge. Often we cannot make a decision freely because of surrounding circumstances: economic, organizational, political and others. Taking into account our goals some decisions are good, others are bad. The problem is how to make the best decision. Nowadays, statistical and mathematical tests are widely used in economy. One of the sciences concerned with in evaluating managers' decisions is operations research. Summing up, operations research deals with the problem of how to gain means and use resources in the most effective way taking into account surrounding limitations. As an example of a place where one of the operations research tools (linear programming) is used as a way of work optimalization is Medical Rehabilitation Unit in John Paul II Hospital in Zamosc. It is a method in which goal function (that is criterion of optimalization) and limitations are linear functions. The problem is to find a solution (regarding limitations) so that the goal function has the greatest value. The aim of the study is to present and encourage managers to use linear programming as a way of improving effectiveness and disclosing weak points of organization.",2002,26/11/2018 12:53,14/04/2020 08:35,,440-443,,,55 Suppl 1,,Wiad Lek,,,,,,,,pol,,,,,,,PMID: 15002281,,,,"Humans; *Models, Organizational; Linear Models; *Operations Research; Efficiency, Organizational; Organizational Objectives; 1; Decision Making, Organizational; Delivery of Health Care/economics/*organization & administration; Health Care Rationing/*methods; Poland; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8MFJ5FFU,journalArticle,2004,"Smith, Dean G.; Nguyen, Anh B.; Peak, Corey N.; Frech, Feride H.",Markov modeling analysis of health and economic outcomes of therapy with valsartan versus amlodipine in patients with type 2 diabetes and microalbuminuria.,Journal of managed care pharmacy : JMCP,,1083-4087 1083-4087,10.18553/jmcp.2004.10.1.26,,"OBJECTIVE: To estimate 8-year health and economic outcomes of the angiotensin II receptor blocker valsartan versus the calcium channel blocker amlodipine in therapy of patients with type 2 diabetes and microalbuminuria based on clinical endpoints from a 6-month randomized controlled clinical trial, the MicroAlbuminuria Reduction With VALsartan (MARVAL) study. METHODS: We developed a Markov model that utilized urinary albumin excretion rate data to project patient distributions to 7 possible health states over 8 years. For each health state, we identified quality-adjustment weights (health utilities) and medical care costs from public sources. The model then calculated mean quality-adjusted survival, medical care costs, and cost-effectiveness ratios for each treatment arm. Treatment arms were compared with the incremental cost-effectiveness ratio. RESULTS: Patients treated with valsartan gained 7 months (mean) per patient of quality-adjusted survival relative to patients treated with amlodipine (77 versus 70 months; P<0.01); valsartan patients also incurred 32,412 dollars (mean) per patient lower medical costs than amlodipine patients (92,058 dollars versus 124,470 dollars; P<0.01). Model results were consistent for each year of analysis and robust to changes in key model parameters. CONCLUSION: This research (1) extends 6-month clinical trial outcomes to an 8-year period, (2) translates health outcomes from technical clinical endpoints to quality-adjusted survival, and (3) estimates economic consequences of therapeutic outcomes. The results quantify the favorable long-term health (i.e., quality-adjusted survival) and economic benefits (i.e., lower total medical costs) of therapy with valsartan, an angiotensin II receptor blocker, versus amlodipine, a calcium channel blocker, in the treatment of patients with type 2 diabetes and microalbuminuria based on an extension of the results of a short-term clinical (MARVAL) trial. These research findings are important to the extent patients with type 2 diabetes and microalbuminuria do not receive the recommended antihypertensive agents that block the renin-angiotensin system (angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers).",2004-02,26/11/2018 12:53,14/04/2020 08:34,,26-32,,1,10,,J Manag Care Pharm,,,,,,,,eng,,,,,,,PMID: 14720103,,,,"Humans; United States; Health Services Research; Outcome and Process Assessment (Health Care); Cost-Benefit Analysis; Treatment Outcome; Markov Chains; Angiotensin-Converting Enzyme Inhibitors/economics/therapeutic use; Calcium Channel Blockers/economics/therapeutic use; 00; Valsartan; Albuminuria/*drug therapy; Amlodipine/economics/*therapeutic use; Diabetes Mellitus, Type 2/*drug therapy/economics; Tetrazoles/economics/*therapeutic use; Valine/analogs & derivatives/economics/*therapeutic use; X",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BVFIZWNJ,journalArticle,2002,"Rodrigues, Bartholomew","Health care reform: opportunities for professional chaplains to build intentional communities of learners by integrating faith, science, quality, and systems thinking.",Journal of health care chaplaincy,,0885-4726 0885-4726,10.1300/J080v13n01_04,,"Albert Einstein once said, ""The significant problems we face cannot be solved at the same level of thinking we were at when we created them"" (www.brainyquote.com). Health care reform has brought professional chaplains to a place of chaos-a place that raises many questions about the past, present and future. This chaos presents tremendous opportunities for professional chaplains to increase their capacities in building intentional communities of learners by integrating faith, science, quality and systems thinking. Pastoral care givers must truly understand the pressures from all sides and the new emerging paradigm of integrated health care delivery. Without this understanding, we will not see the opportunities and challenges of integrating pastoral and spiritual care in the emerging structures and systems. The future of chaplaincy largely will depend on the quality of the data, quality of our conversations and our ability to thinking together through dialogue.",2002,26/11/2018 12:53,14/04/2020 08:35,,195-211,,1,13,,J Health Care Chaplain,,,,,,,,eng,,,,,,,PMID: 14682102,,,,*Health Care Reform; Humans; United States; Quality Improvement; Systems Theory; *Health Services Research; Cost Savings; Health Care Reform; Chaplaincy Service; Hospital – Evaluation; Patient Advocacy; Technology – Trends; 00; *Outcome and Process Assessment (Health Care); *Pastoral Care/education; *Religion and Science; Managed Care Programs; Spirituality; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KSTSQ3QT,journalArticle,2003,"Best, Allan; Moor, Gregg; Holmes, Bev; Clark, Pamela I.; Bruce, Ted; Leischow, Scott; Buchholz, Kaye; Krajnak, Judith",Health promotion dissemination and systems thinking: towards an integrative model.,American journal of health behavior,,1087-3244 1087-3244,,,"OBJECTIVE: To help close the gap between health promotion research and practice by using systems thinking. METHODS: We reviewed 3 national US tobacco control initiatives and a project (ISIS) that had introduced systems thinking to tobacco control, speculating on ways in which systems thinking may add value to health promotion dissemination and implementation in general. RESULTS: The diversity of disciplines involved in tobacco control have created disconnection in the field; systems thinking is necessary to increase the impact of strategies. CONCLUSION: Systems thinking has potential to improve synthesis, translation, and dissemination of research findings in other health promotion initiatives.",2003-12,26/11/2018 12:53,14/04/2020 08:34,,S206-216,,,27 Suppl 3,,Am J Health Behav,,,,,,,,eng,,,,,,,PMID: 14672381,,,,"Humans; United States; Adult; Female; Male; Child; Adolescent; Pregnancy; Child, Preschool; *Systems Theory; Smoking/psychology; Diffusion of Innovation; Family/psychology; Health Promotion/*methods; 1; *Smoking Prevention; Primary Prevention/*methods; Tobacco Use Cessation/*methods/psychology; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CCRSQG9A,journalArticle,2003,"You, Joyce H. S.; Chan, Fredric W. H.; Wong, Raymond S. M.; Cheng, Gregory",Cost-effectiveness of two models of management for patients on chronic warfarin therapy--a Markov model analysis.,Thrombosis and haemostasis,,0340-6245 0340-6245,10.1160/TH03-06-0367,,"Allocation of additional resources for establishing or expanding anticoagulation clinic (AC) services is a significant concern for healthcare decision-makers when the payer is also the provider of the healthcare system. The majority of anticoagulated patients in Hong Kong are managed by routine medical care (RMC) instead of ACs, possibly due to the lack of local cost-effectiveness analysis of the AC setting. The aim was to compare the clinical and economic outcomes of anticoagulated patients who were managed by AC or RMC from the perspective of a public health organization in Hong Kong. A Markov model was designed to simulate, over 10 years, the economic and clinical outcomes of patients receiving chronic warfarin therapy managed by AC or RMC. The transition probabilities were derived from literature. Resource utilization was retrieved from patients managed by AC and RMC in Hong Kong. Sensitivity analysis was conducted to examine the robustness of the model. The total number of events per 100 patient-years and the direct medical cost per patient-year in the AC and RMC groups were 9.5 and USD 840, and, 19.3 and USD 1,179, respectively. The results of the model were sensitive to the variation of the probability of major bleeding in the AC group. In conclusion, the coordinated care provided by an anticoagulation clinic appears to be more cost-effective than routine medical care in the management of warfarin therapy from the perspective of public health organization in Hong Kong.",2003-12,26/11/2018 12:53,14/04/2020 08:35,,1106-1111,,6,90,,Thromb Haemost,,,,,,,,eng,,,,,,,PMID: 14652644,,,,Humans; Cost-Benefit Analysis; Disease Management; Treatment Outcome; Health Care Costs; *Markov Chains; Chronic Disease; Ambulatory Care Facilities; Algorithms; Public Health Administration; Hemorrhage/chemically induced/economics; Warfarin/adverse effects/*economics/*therapeutic use; 00; 140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, N6U5EJ4Y,journalArticle,2003,"Zaric, Gregory S.",The impact of ignoring population heterogeneity when Markov models are used in cost-effectiveness analysis.,Medical decision making : an international journal of the Society for Medical Decision Making,,0272-989X 0272-989X,10.1177/0272989X03256883,,"Many factors related to the spread and progression of diseases vary throughout a population. This heterogeneity is frequently ignored in cost-effectiveness analyses by using average or representative values or by considering multiple risk groups. The author explores the impact that such simplifying assumptions may have on the results and interpretation of cost-effectiveness analyses when Markov models are used to calculate the costs and health impact of interventions. A discrete-time Markov model for a disease is defined, and 5 potential interventions are considered. Health benefits, costs, and incremental cost-effectiveness ratios are calculated for each intervention. It is assumed that the population is heterogeneous with respect to the probability of becoming sick. Ignoring this heterogeneity may lead to optimistic or pessimistic estimates of cost-effectiveness ratios, depending on the intervention and, in some cases, the parameter values. Implications are discussed of this finding on the use of league tables and on comparisons of cost-effectiveness ratios versus commonly accepted threshold values.",2003-10,26/11/2018 12:53,14/04/2020 08:35,,379-396,,5,23,,Med Decis Making,,,,,,,,eng,,,,,,,PMID: 14570296,,,,"Humans; Cost-Benefit Analysis; *Markov Chains; Health Status; *Models, Econometric; *Population; Life Tables; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GSDREXRP,journalArticle,2003,"Karnon, Jonathan",Alternative decision modelling techniques for the evaluation of health care technologies: Markov processes versus discrete event simulation.,Health economics,,1057-9230 1057-9230,10.1002/hec.770,,"Markov models have traditionally been used to evaluate the cost-effectiveness of competing health care technologies that require the description of patient pathways over extended time horizons. Discrete event simulation (DES) is a more flexible, but more complicated decision modelling technique, that can also be used to model extended time horizons. Through the application of a Markov process and a DES model to an economic evaluation comparing alternative adjuvant therapies for early breast cancer, this paper compares the respective processes and outputs of these alternative modelling techniques. DES displays increased flexibility in two broad areas, though the outputs from the two modelling techniques were similar. These results indicate that the use of DES may be beneficial only when the available data demonstrates particular characteristics.",2003-10,26/11/2018 12:53,14/04/2020 08:34,,837-848,,10,12,,Health Econ,,,,,,,,eng,"Copyright 2002 John Wiley & Sons, Ltd.",,,,,,PMID: 14508868,,,,"Humans; Quality-Adjusted Life Years; Female; Middle Aged; *Models, Economic; Aged; *Markov Chains; Aged, 80 and over; Monte Carlo Method; *Decision Support Techniques; 1; Chemotherapy, Adjuvant/adverse effects/economics; Antineoplastic Agents, Hormonal/adverse effects/therapeutic use; Antineoplastic Combined Chemotherapy Protocols/adverse effects/economics/therapeutic use; Breast Neoplasms/drug therapy/economics/secondary; Cost-Benefit Analysis/methods/statistics & numerical data; Tamoxifen/adverse effects/economics/therapeutic use; Technology Assessment, Biomedical/*economics; ******To read; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, N3KTBW7P,journalArticle,2003,"Madigan, Elizabeth A.; Tullai-McGuinness, Susan; Fortinsky, Richard H.",Accuracy in the Outcomes and Assessment Information Set (OASIS): results of a video simulation.,Research in nursing & health,,0160-6891 0160-6891,10.1002/nur.10094,,"There is little information regarding the accuracy of the Outcomes and Assessment Information Set (OASIS), the patient assessment tool mandated for use in Medicare-funded home health care. The purposes of this study were to evaluate the accuracy of OASIS completion by home health nurses and rehabilitation therapists, to compare responses of nurses and therapists, and to determine whether dispersion of answers would affect the home health resource group (HHRG) to which patients were assigned for Medicare home health care payments to agencies. Using a video simulation of admission and discharge visits, 436 clinicians from 29 Ohio home health care agencies scored selected OASIS items. Although the majority of the items were rated accurately, discrepancies were found between clinician responses and the ""correct"" answer on several items. Nurses and therapists provided similar ratings on most items studied, but for most cases in which discrepancies were found, nurses were more likely to agree with the ""correct"" answer. Discrepancies most often led to patients being assigned to lower-payment HHRGs. Continued monitoring of OASIS data collection accuracy is recommended to maximize the value of the OASIS instrument in home health care research, practice, and policy.",2003-08,26/11/2018 12:53,14/04/2020 08:34,,273-283,,4,26,,Res Nurs Health,,,,,,,,eng,"Copyright 2003 Wiley Periodicals, Inc.",,,,,,PMID: 12884416,,,,Humans; Medicare; Video Recording; Ohio; Role Playing; Outcome and Process Assessment (Health Care)/*methods; Patient-Centered Care/*methods; *Hip Fractures/nursing/rehabilitation; *Home Care Services; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 3QM57Y2L,journalArticle,2003,"Pluto, Delores M.; Hirshorn, Barbara A.",Process mapping as a tool for home health network analysis.,Home health care services quarterly,,0162-1424 0162-1424,10.1300/J027v22n02_01,,"Process mapping is a qualitative tool that allows service providers, policy makers, researchers, and other concerned stakeholders to get a ""bird's eye view"" of a home health care organizational network or a very focused, in-depth view of a component of such a network. It can be used to share knowledge about community resources directed at the older population, identify gaps in resource availability and access, and promote on-going collaborative interactions that encourage systemic policy reassessment and programmatic refinement. This article is a methodological description of process mapping, which explores its utility as a practice and research tool, illustrates its use in describing service-providing networks, and discusses some of the issues that are key to successfully using this methodology.",2003,26/11/2018 12:53,14/04/2020 08:35,,Jan-16,,2,22,,Home Health Care Serv Q,,,,,,,,eng,,,,,,,PMID: 12870709,,,,Humans; United States; *Systems Analysis; Continuity of Patient Care; Community Health Planning/*organization & administration; Process Assessment (Health Care); Cooperative Behavior; Home Care Services/*organization & administration; Interinstitutional Relations; Institutional Management Teams; Community Networks/*organization & administration; 00; Software Design; Health Services Accessibility/organization & administration; Maps as Topic; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, P5HN4IUW,journalArticle,2003,"Boll, A. P. M.; Severens, J. L.; Verbeek, A. L. M.; van der Vliet, J. A.",Mass screening on abdominal aortic aneurysm in men aged 60 to 65 years in The Netherlands. Impact on life expectancy and cost-effectiveness using a Markov model.,European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery,,1078-5884 1078-5884,,,"OBJECTIVES: To predict the costs and effects on life expectancy of an AAA screening programme. METHODS: A Markov model was designed to compare the effects of a single screening for a cohort of men 60-65 years with the current no screening strategy. The following health states were distinguished: no AAA, unknown small AAA, follow-up small AAA, unknown large AAA, repaired AAA, rejected large AAA and death. Transition rates between the health states were simulated using cycle times of one year. Transition probabilities were derived from literature and a previous feasibility study. Incremental costs per life year saved were calculated. Sensitivity analyses and discounting for future effects were performed. RESULTS: The expected individual AAA costs for non-screening and AAA screening were euro; 196 and euro; 530 respectively. A difference of 3.5 months life expectancy was found in favour of screening leading to euro; 1176/life-year gained. Costs increased as compliance fell. With a discount rate of 4% the costs are euro; 2021/life-year gained. CONCLUSIONS: One-time ultrasonographic screening for AAA in men aged 60-65 years appears to be cost-effective.",2003-07,26/11/2018 12:53,14/04/2020 08:34,,74-80,,1,26,,Eur J Vasc Endovasc Surg,,,,,,,,eng,,,,,,,PMID: 12819652,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Male; Middle Aged; Aged; Markov Chains; Models, Statistical; Mass Screening/*economics; *Life Expectancy; Aortic Aneurysm, Abdominal/*diagnostic imaging/economics/epidemiology; Netherlands/epidemiology; Ultrasonography/economics; 00; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8VSEHSCB,journalArticle,2003,"Carroll, Joan F.",Isolated heart responsiveness to beta-simulation after exercise training in obesity.,Medicine and science in sports and exercise,,0195-9131 0195-9131,10.1249/01.MSS.0000058356.31664.00,,"PURPOSE: Exercise training results in many health benefits, but few studies have focused on whether exercise training might attenuate the adverse effects of obesity on heart function. Therefore, the purpose of this study was to determine whether exercise training attenuated obesity-related decreases in systolic contractile function in response to beta-adrenergic stimulation, using the rabbit model of obesity. METHODS: Female New Zealand white rabbits were divided into four groups: lean sedentary, lean exercise-trained, obese sedentary, and obese exercise-trained. Obese rabbits were fed an ad libitum high-fat diet. Exercise-trained rabbits underwent a 12-wk progressive treadmill exercise training protocol. After 12 wk, the Langendorff isolated heart method was used to study developed pressure, +dP/dt, and -dP/dt responses to increasing concentrations of isoproterenol (10(-9)--3 x 10(-7) M). Log concentration-response data were fit to a sigmoidal function, using a four-parameter (minimum, maximum, EC(50), slope) logistic equation. Groups were compared using a 2 x 2 analysis of variance. RESULTS: Although obesity shifted the concentration-response curves for developed pressure, +dP/dt, and -dP/dt to the right as indicated by an increase in the EC(50) (P < or = 0.05), there was no effect of exercise training on any of the logistic regression parameters. EC(50) (log M) values for combined lean versus combined obese were -8.50 +/- 0.7 vs -8.20 +/- 0.09 (developed pressure), -8.04 +/- 0.06 vs -7.68 +/- 0.07 (+dP/dt), and -8.17 +/- 0.07 vs -7.91 +/- 0.09 (-dP/dt). CONCLUSION: These results confirm the negative effect of obesity on responsiveness of the isolated heart to beta-adrenergic stimulation but indicate that exercise training does not significantly attenuate obesity-related changes.",2003-04,26/11/2018 12:53,14/04/2020 08:34,,548-554,,4,35,,Med Sci Sports Exerc,,,,,,,,eng,,,,,,,PMID: 12673135,,,,"Humans; Female; Animals; 00; *Exercise Therapy; Adrenergic beta-Agonists/administration & dosage/pharmacology; Disease Models, Animal; Isoproterenol/administration & dosage/pharmacology; Myocardial Contraction/*physiology; Obesity/*complications/*therapy/veterinary; Organ Culture Techniques; Physical Conditioning, Animal/*physiology; Rabbits; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, R22T4A4P,journalArticle,2003,"Cooper, Nicola J.; Sutton, Alex J.; Mugford, Miranda; Abrams, Keith R.",Use of Bayesian Markov Chain Monte Carlo methods to model cost-of-illness data.,Medical decision making : an international journal of the Society for Medical Decision Making,,0272-989X 0272-989X,10.1177/0272989X02239653,,"It is well known that the modeling of cost data is often problematic due to the distribution of such data. Commonly observed problems include 1) a strongly right-skewed data distribution and 2) a significant percentage of zero-cost observations. This article demonstrates how a hurdle model can be implemented from a Bayesian perspective by means of Markov Chain Monte Carlo simulation methods using the freely available software WinBUGS. Assessment of model fit is addressed through the implementation of two cross-validation methods. The relative merits of this Bayesian approach compared to the classical equivalent are discussed in detail. To illustrate the methods described, patient-specific non-health-care resource-use data from a prospective longitudinal study and the Norfolk Arthritis Register (NOAR) are utilized for 218 individuals with early inflammatory polyarthritis (IP). The NOAR database also includes information on various patient-level covariates.",2003-02,26/11/2018 12:53,14/04/2020 08:34,,38-53,,1,23,,Med Decis Making,,,,,,,,eng,,,,,,,PMID: 12583454,,,,"Humans; Reproducibility of Results; Markov Chains; *Computer Simulation; Monte Carlo Method; *Bayes Theorem; *Models, Econometric; *Cost of Illness; 00; Arthritis/economics; Costs and Cost Analysis/statistics & numerical data; 100; 120",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4U8MQ7XB,journalArticle,2003,"Ayuku, David; Odero, Wilson; Kaplan, Charles; De Bruyn, Rene; De Vries, Marten",Social network analysis for health and social interventions among Kenyan scavenging street children.,Health policy and planning,,0268-1080 0268-1080,,,"Street children are a high priority for health policy and service planning in Kenya. Poverty, wars, famine and disease have resulted in street children having a persistent presence in African cities and towns. The Maastricht Social Network Analysis (MSNA) was implemented as the core instrument in a battery to measure the health status of the street children. Owing to the absence of census data of street children in Kenya and the difficulty in tracking this mobile population, we implemented a mixed snowball and convenience sampling design to recruit research subjects. Three hundred street and orphanage children, and 100 primary school children as a control group, were included in the study. The MSNA provided a social diagnosis that complements the clinical diagnosis of the health status of the sample. Only one main methodological question is presented: is the MSNA applicable to describe the personal social networks of (1). children and of (2). people living in a Kenyan culture? Qualitative field observations, key informant interviews and focus groups inform the adaptation of the MSNA instrument, and improve its face validity. A case series analysis is presented. The main result is that the street children population consists of distinct subgroups defined by the UNICEF classification as 'on' and 'of' the street and by gender. Street children networks have some notable deficiencies depending on the subgroup. Constant across the groups is the deficiency of service providers in their networks. The conclusion is that the MSNA is a suitable instrument for obtaining a social diagnosis and gathering other useful information that helps in understanding the social and health backgrounds, status and daily experiences of Kenyan scavenging street children. Applying the MSNA protocol was successful in the diagnosis and interpretation of the findings.",2003-03,26/11/2018 12:53,14/04/2020 08:34,,109-118,,1,18,,Health Policy Plan,,,,,,,,eng,,,,,,,PMID: 12582114,,,,Humans; Health Status Indicators; Female; Male; Qualitative Research; Child; Cross-Sectional Studies; *Social Support; Child Health Services/*organization & administration; Health Priorities; 00; Social Work/*organization & administration; Child Welfare/*ethnology; Homeless Youth/classification/*ethnology; Kenya/epidemiology; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4JLA345A,journalArticle,2003,"van Mens-Verhulst, Janneke; van Dijkum, Cor; van Kuijk, Edzel; Lam, Niek",The self-regulation of fatigue and associated complaints: an exploratory simulation.,Patient education and counseling,,0738-3991 0738-3991,,,"A computer simulation has been developed that reflects the microdynamics of dealing with fatigue and associated complaints. The theoretical base was derived from Leventhal, Nerenz and Steele's self-regulation model; the empirical base from a large-scale diary study carried out over a period of 3 weeks. The simulation results demonstrate that the process of self-regulation is non-linear. Consequently, some patient education assumptions are challenged: that individuals suffering from fatigue and associated complaints are likely to follow a similar trajectory, that interventions should not be started until after a 6 weeks delay, and that an intervention always produces the same results. These insights may be generalised to other health complaints that have no medical explanation.",2003-01,26/11/2018 12:53,14/04/2020 08:35,,53-57,,1,49,,Patient Educ Couns,,,,,,,,eng,,,,,,,PMID: 12527153,,,,"Humans; Netherlands; *Computer Simulation; Systems Analysis; Linear Models; Time Factors; Health Knowledge, Attitudes, Practice; Health Services Needs and Demand; Problem Solving; Health Behavior; *Adaptation, Psychological; Life Style; *Models, Psychological; Attitude to Health; 00; Nonlinear Dynamics; *Fatigue/prevention & control/psychology; *Self Care/methods/psychology; Causality; Feedback, Psychological; Patient Education as Topic/organization & administration; Self-Assessment; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ABE4RB27,journalArticle,2002,"Rukavishnikov, V. S.; Matorova, N. I.; Efimova, N. V.; D'iakovich, M. P.; Baturin, V. A.",[Use of mathematical simulation models in health-environment systems].,Gigiena i sanitariia,,0016-9900 0016-9900,,,,2002-12,26/11/2018 12:53,14/04/2020 08:35,,65-66,,6,,,Gig Sanit,,,,,,,,rus,,,,,,,PMID: 12516143,,,,"Humans; Adult; Female; Male; *Public Health; Child; Pregnancy; Child, Preschool; Infant; Prospective Studies; Russia/epidemiology; 1; *Mathematics; Environmental Exposure/*adverse effects/*statistics & numerical data; Environmental Illness/*epidemiology/etiology; Hazardous Substances/*adverse effects; Pregnancy Complications/etiology; Statistics as Topic/methods; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 426YMS5J,journalArticle,2002,"Mohamed, E. I.; Linder, R.; Perriello, G.; Di Daniele, N.; Poppl, S. J.; De Lorenzo, A.",Predicting Type 2 diabetes using an electronic nose-based artificial neural network analysis.,"Diabetes, nutrition & metabolism",,0394-3402 0394-3402,,,"Diabetes is a major health problem in both industrial and developing countries, and its incidence is rising. Although detection of diabetes is improving, about half of the patients with Type 2 diabetes are undiagnosed and the delay from disease onset to diagnosis may exceed 10 yr. Thus, earlier detection of Type 2 diabetes and treatment of hyperglycaemia and related metabolic abnormalities is of vital importance. The objectives of the present study were to examine urine samples from Type 2 diabetic patients and healthy volunteers using the electronic nose technology and to evaluate possible application of data classification methods such as self-learning artificial neural networks (ANN) and logistic regression (LR) in comparison with principal components analysis (PCA). Urine samples from Type 2 diabetic patients and healthy controls were processed randomly using a simple 8-sensors electronic nose and individual electronic nose patterns were qualitatively classified using the ""Approximation and Classification of Medical Data"" (ACMD) network based on 2 output neurons, binary LR analysis and PCA. Distinct classes were found for Type 2 diabetic subjects and controls using PCA, which had a 96.0% successful classification percentage mean while qualitative ANN analysis and LR analysis had successful classification percentages of 92.0% and 88.0%, respectively. Therefore, the ACMD network is suitable for classifying medical and clinical data.",2002-08,26/11/2018 12:53,14/04/2020 08:34,,215-221,,4,15,,Diabetes Nutr Metab,,,,,,,,eng,,,,,,,PMID: 12416658,,,,"Humans; Female; Male; Middle Aged; Aged; Sensitivity and Specificity; Logistic Models; Body Mass Index; 00; *Neural Networks (Computer); Blood Glucose/analysis; Breath Tests; Diabetes Mellitus, Type 2/*diagnosis/*urine; Fasting; Glycosuria; Nose; Odorants/*analysis; Proteinuria/urine; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, SZUN64JC,journalArticle,2002,"Pronk, Nicolaas P.; Boucher, Jackie L.; Gehling, Eve; Boyle, Raymond G.; Jeffery, Robert W.",A platform for population-based weight management: description of a health plan-based integrated systems approach.,The American journal of managed care,,1088-0224 1088-0224,,,"OBJECTIVES: To describe an integrated, operational platform from which mail- and telephone-based health promotion programs are implemented and to specifically relate this approach to weight management programming in a managed care setting. APPROACH: In-depth description of essential systems structures, including people, computer technology, and decision-support protocols. The roles of support staff, counselors, a librarian, and a manager in delivering a weight management program are described. Information availability using computer technology is a critical component in making this system effective and is presented according to its architectural layout and design. Protocols support counselors and administrative support staff in decision making, and a detailed flowchart presents the layout of this part of the system. This platform is described in the context of a weight management program, and we present baseline characteristics of 1801 participants, their behaviors, self-reported medical conditions, and initial pattern of enrollment in the various treatment options. CONCLUSION: Considering the prevalence and upward trend of overweight and obesity in the United States, a need exists for robust intervention platforms that can systematically support multiple types of programs. Weight management interventions implemented using this platform are scalable to the population level and are sustainable over time despite the limits of defined resources and budgets. The present article describes an innovative approach to reaching a large population with effective programs in an integrated, coordinated, and systematic manner. This comprehensive, robust platform represents an example of how obesity prevention and treatment research may be translated into the applied setting.",2002-10,26/11/2018 12:53,14/04/2020 08:35,,847-857,,10,8,,Am J Manag Care,,,,,,,,eng,,,,,,,PMID: 12395953,,,,"Humans; Female; Male; Middle Aged; Decision Support Techniques; United States/epidemiology; Prevalence; Life Style; 1; Delivery of Health Care, Integrated/*organization & administration; Health Promotion/methods/*organization & administration; Managed Care Programs/organization & administration; Obesity/epidemiology/*prevention & control; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, P9FD3I5S,journalArticle,2002,"Hupert, Nathaniel; Mushlin, Alvin I.; Callahan, Mark A.",Modeling the public health response to bioterrorism: using discrete event simulation to design antibiotic distribution centers.,Medical decision making : an international journal of the Society for Medical Decision Making,,0272-989X 0272-989X,,,"BACKGROUND: Post-exposure prophylaxis is a critical component of the public health response to bioterrorism. Computer simulation modeling may assist in designing antibiotic distribution centers for this task. METHODS: The authors used discrete event simulation modeling to determine staffing levels for entry screening, triage, medical evaluation, and drug dispensing stations in a hypothetical antibiotic distribution center operating in low, medium, and high disease prevalence bioterrorism response scenarios. Patient arrival rates and processing times were based on prior mass prophylaxis campaigns. Multiple sensitivity analyses examined the relationship between average staff utilization rate (UR) (i.e., percentage of time occupied in patient contact) and capacity of the model to handle surge arrivals. RESULTS: Distribution center operation required from 93 staff for the low-prevalence scenario to 111 staff for the high-prevalence scenario to process approximately 1000 people per hour within the baseline model assumptions. Excess capacity to process surge arrivals approximated (1-UR) for triage staffing. CONCLUSIONS: Discrete event simulation modeling is a useful tool in developing the public health infrastructure for bioterrorism response. Live exercises to validate the assumptions and outcomes presented here may improve preparedness to respond to bioterrorism.",2002-10,26/11/2018 12:53,14/04/2020 08:34,,S17-25,,5 Suppl,22,,Med Decis Making,,,,,,,,eng,,,,,,,PMID: 12369227,,,,Humans; *Computer Simulation; United States/epidemiology; Time Factors; *Public Health Practice; Prevalence; Sensitivity and Specificity; Disaster Planning/*organization & administration; 00; Workload; Anti-Bacterial Agents/*supply & distribution; Bioterrorism/*prevention & control/statistics & numerical data; Mass Screening/organization & administration; Medication Systems/*organization & administration; Personnel Staffing and Scheduling/*organization & administration; Pharmacies/*organization & administration; Triage/organization & administration; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, RIST5EHF,journalArticle,2002,"Riebschleger, Joanne",Community mental health professionals' theoretical assumptions about families: responses to a practice simulation vignette.,Psychiatric rehabilitation journal,,1095-158X 1095-158X,,,"Seventy-three community mental health professionals read a practice simulation vignette about a man with increased schizophrenia symptoms who appears at a community mental health agency accompanied by his parents. Professionals reported their levels of agreement that the parent/s may play a role in the man's schizophrenia symptoms and/or mental health treatment, i.e., serving as treatment resources; expecting consultation from professionals; serving as partners and allies; expressing negative emotions; expressing double bind communication; engaging in hostile behavior per the schizophrenogenic mother; having marriage conflicts; and also having a psychiatric disability. Professionals reported their level of agreement that the parents may be experiencing responses to their son's schizophrenia such as coping; grieving; adjusting to a biological illness; dealing with caregiving responsibilities/burdens; and remaining strong, resilient people. Findings revealed that this sample of mental health professionals most strongly agreed that families are coping, grieving, and positive treatment resources.",2002,26/11/2018 12:53,14/04/2020 08:35,,91-96,,1,26,,Psychiatr Rehabil J,,,,,,,,eng,,,,,,,PMID: 12171288,,,,"Humans; Cost of Illness; Adaptation, Psychological; Counseling; 00; Family Health; *Attitude; *Family; *Professional-Family Relations; Community Mental Health Services/*manpower; Mental Disorders/psychology; Social Work/manpower; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 2V57KENL,journalArticle,2002,"Romagnuolo, Joseph; Meier, Michael A.; Sadowski, Daniel C.",Medical or surgical therapy for erosive reflux esophagitis: cost-utility analysis using a Markov model.,Annals of surgery,,0003-4932 0003-4932,10.1097/01.SLA.0000021641.86331.F7,,"OBJECTIVE: To compare the cost and utility of healing and maintenance regimens of omeprazole and laparoscopic Nissen fundoplication (LNF) in the framework of the Canadian medical system. SUMMARY BACKGROUND DATA: Medical therapy with proton pump inhibitors for endoscopically proven reflux esophagitis is a safe and effective treatment option. Of late, the surgical treatment of choice for this disease has become LNF. METHODS: The authors' base case was a 45-year-old man with erosive reflux esophagitis refractory to H2-blockers. A cost-utility analysis was performed comparing the two strategies. A two-stage Markov model (healing and maintenance phases) was used to estimate costs and utilities with a time horizon of 5 years. Discounted direct costs were estimated from the perspective of a provincial health ministry, and discounted quality-of-life estimates were derived from the medical literature. Sensitivity analyses were performed to test the robustness of the model to the authors' assumptions and to determine thresholds. A Monte Carlo simulation of 10,000 patients was used to estimate variances and 95% interpercentile ranges. RESULTS: For the 5-year period studied, LNF was less expensive than omeprazole (3519.89 dollars vs. 5464.87 dollars per patient) and became the more cost-effective option at 3.3 years of follow-up. The authors found that 20 mg/day omeprazole would have to cost less than 38.60 dollars per month before medical therapy became cost effective; conversely, the cost of LNF would have to be more than 5,273.70 dollars or the length of stay more than 4.2 days for medical therapy to be cost effective. Estimates of quality-adjusted life-years did not differ significantly between the two treatment options, and the incremental cost for medical therapy was 129,665 dollars per quality-adjusted life-years gained. CONCLUSIONS: For patients with severe esophagitis, LNF is a cost-effective alternative to long-term maintenance therapy with proton pump inhibitors.",2002-08,26/11/2018 12:53,14/04/2020 08:35,,191-202,,2,236,,Ann Surg,,,,,,,,eng,,,,,,,PMID: 12170024 PMCID: PMC1422565,,,,"Humans; Canada; Cost-Benefit Analysis; Male; Middle Aged; Markov Chains; Quality of Life; Monte Carlo Method; Time Factors; 00; Enzyme Inhibitors/*economics/therapeutic use; Esophagitis, Peptic/*drug therapy/economics/*surgery; Fundoplication/*economics; Laparoscopy/*economics; Omeprazole/*economics/therapeutic use; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GACSCG3T,journalArticle,2001,"Kennedy, A.; Rogers, A.",Improving self-management skills: a whole systems approach.,British journal of nursing (Mark Allen Publishing),,0966-0461 0966-0461,10.12968/bjon.2001.10.11.10435,,"This article outlines the rationale behind an approach developed at the National Primary Care Research and Development Centre (NPCRDC) to improve patients' abilities to self-manage their conditions with the support of services provided by the NHS. The approach is systematic and requires involvement of patients in the development of information, changing access arrangements to health services and promoting a patient-centred approach to care. A programme of research and development is currently being undertaken at The University of Manchester by researchers based at NPCRDC to investigate the effectiveness of this approach. The evidence base for the strategy under investigation is discussed and proposals are made for the role of nurses as facilitators for the self-management agenda in the NHS.",14/06/2001,26/11/2018 12:53,14/04/2020 08:34,,734-737,,11,10,,Br J Nurs,,,,,,,,eng,,,,,,,PMID: 12048491,,,,"Humans; Health Services Accessibility/standards; Evidence-Based Medicine; United Kingdom; *Social Support; Attitude of Health Personnel; *Systems Integration; Health Care Reform; Total Quality Management/*organization & administration; 00; Nurse's Role; Philosophy, Nursing; Information Services/standards; Patient-Centered Care/*standards; Self Care/*standards; State Medicine/organization & administration; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YU2YH3HW,journalArticle,2002,"Fenwick, Elisabeth; Wilson, Jonathan; Sculpher, Mark; Claxton, Karl",Pre-operative optimisation employing dopexamine or adrenaline for patients undergoing major elective surgery: a cost-effectiveness analysis.,Intensive care medicine,,0342-4642 0342-4642,10.1007/s00134-002-1257-y,,"OBJECTIVE: To compare the cost and cost-effectiveness of a policy of pre-operative optimisation of oxygen delivery (using either adrenaline or dopexamine) to reduce the risk associated with major elective surgery, in high-risk patients. METHODS: A cost-effectiveness analysis using data from a randomised controlled trial (RCT). In the RCT 138 patients undergoing major elective surgery were allocated to receive pre-operative optimisation employing either adrenaline or dopexamine (assigned randomly), or to receive routine peri-operative care. Differential health service costs were based on trial data on the number and cause of hospital in-patient days and the utilisation of health care resources. These were costed using unit costs from a UK hospital. The cost-effectiveness analysis related differential costs to differential life-years during a 2 year trial follow-up. RESULTS: The mean number of in-patient days was 16 in the pre-optimised groups (19 adrenaline; 13 dopexamine) and 22 in the standard care group. The number (%) of deaths, over a 2 year follow-up, was 24 (26%) in the pre-optimised groups and 15 (33%) in the standard care group. The mean total costs were EUR 11,310 in the pre-optimised groups and EUR 16,965 in the standard care group. Life-years were 1.68 in the pre-optimised groups and 1.46 in the standard care group. The probability that pre-operative optimisation is less costly than standard care is 98%. The probability that it dominates standard care is 93%. CONCLUSIONS: Based on resource use and effectiveness data collected in the trial, pre-operative optimisation of high-risk surgical patients undergoing major elective surgery is cost-effective compared with standard treatment.",2002-05,26/11/2018 12:53,14/04/2020 08:34,,599-608,,5,28,,Intensive Care Med,,,,,,,,eng,,,,,,,PMID: 12029409,,,,Humans; Health Services Research; Cost-Benefit Analysis; Randomized Controlled Trials as Topic; Retrospective Studies; Bayes Theorem; Hospital Costs; Dopamine/analogs & derivatives/*therapeutic use; Elective Surgical Procedures/adverse effects/mortality; Epinephrine/*therapeutic use; Hospital Mortality; Length of Stay/statistics & numerical data; Oxygen/*administration & dosage; Preoperative Care/*economics/*methods; Vasoconstrictor Agents/*therapeutic use; Vasodilator Agents/*therapeutic use; 00; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, XVC6CHG5,journalArticle,2000,"Silveira, D. T.",[Intervention in the process of work-health-disease based on the Betty Neuman's systems model].,Revista gaucha de enfermagem,,0102-6933 0102-6933,,,"This article proposes a referential landmark directed to the worker's area, attempting to answer theoretical and methodological needs in this field of action and professional intervention. The controversy of the relation work-health-disease and its implications to nursing are very challenging and, at the same time, quite intriguing as we seek for its interrelationships. Therefore, we intend to unfold them adopting the structural path of The Neuman Systems Model, systematizing a proposal of nursing action compromised with the relation work-health-disease. Also, we wish to investigate stress factors at work, environment and individual resources to deal with them, and the goals established to the interaction between nurse and worker. This interaction is seen as fundamental to the proposal of educational and/or assistencial actions to the worker's health. It is our intention to contribute with information and propositions to induce reflective thought and debate about the subject.",2000-01,26/11/2018 12:53,14/04/2020 08:35,,31-43,,1,21,,Rev Gaucha Enferm,,,,,,,,por,,,,,,,PMID: 11998474,,,,"Humans; 00; *Models, Nursing; *Occupational Health Nursing; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4H3YH6CX,journalArticle,2002,"Anderson, James G.",Evaluation in health informatics: social network analysis.,Computers in biology and medicine,,0010-4825 0010-4825,,,"Social network analysis comprises a set of research methods that can be used to analyze the relationships among entities such as people, departments, and organizations. The purpose of the analysis is to discover patterns of relationships that affect both individual and organizational attitudes and behavior such as the adoption, diffusion, and use of new medical informatics applications. This paper presents an introduction to the concepts and methods of social network analysis. Several applications to health informatics are described.",2002-05,26/11/2018 12:53,14/04/2020 08:34,,179-193,,3,32,,Comput Biol Med,,,,,,,,eng,,,,,,,PMID: 11922934,,,,"Humans; Evaluation Studies as Topic; Cooperative Behavior; Community Networks; Sociology; 00; Attitude; Medical Records Systems, Computerized; Equipment Design; Hospital Information Systems/standards; Medical Informatics/*standards; Technology Assessment, Biomedical; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, IDJIMVXV,journalArticle,2001,"Tatti, P.; Lehmann, E. D.",Use of the AIDA diabetes simulation software--www.2aida.org--as an interactive educational tool for teaching student nurses.,Diabetes technology & therapeutics,,1520-9156 1520-9156,10.1089/15209150152811315,,"In previous ""Diabetes Information Technology & WebWatch"" columns, various user experiences with an interactive educational virtual diabetes patient simulator, called AIDA, have been documented. The simulator is available free of charge from www.2aida.org on the Web. In the 5+ years since the program was first made available on the Internet, over 125,000 people have visited the AIDA Website and over 27,000 copies of the program have been downloaded, gratis. User comments that have been received about the program have highlighted some of the many and varied ways in which a range of people have been applying the diabetes simulations in their own particular situations and practices. Inevitably, up to now, a great deal of attention has focused on use of the program by individuals with diabetes and their relatives, as well as by health-care professionals such as diabetologists/endocrinologists, diabetes educators, and primary care physicians (general practitioners [GPs]). However, an important group of health-carers involved in the provision of day-to-day care for many people with diabetes are nurses. The current ""Diabetes Information Technology & WebWatch"" column overviews a workshop held in June 2001 in Italy to gain experience with application of the AIDA diabetes simulation approach as a teaching tool for student nurses. Feedback obtained from participants attending the workshop was generally very positive, with the student nurses reporting the simulation approach to be both of interest and of use. Further workshops involving other health-care students and professionals-in particular, medical students and qualified nurses-are planned.",2001,26/11/2018 12:53,14/04/2020 08:35,,655-664,,4,3,,Diabetes Technol Ther,,,,,,,,eng,,,,,,,PMID: 11911181,,,,"Humans; *Software; *Computer Simulation; Educational Measurement; *Students, Nursing; *Computer-Assisted Instruction; Internet; 00; *Education, Nursing; *Diabetes Mellitus; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, HWN2PPA8,journalArticle,2001,"Chan, C. P.","Implications of organizational learning for nursing managers from the cultural, interpersonal and systems thinking perspectives.",Nursing inquiry,,1320-7881 1320-7881,,,"This paper discusses the implications of organizational learning to healthcare administrators, in particular nursing managers, from the cultural, interpersonal and systems thinking perspectives. In the various perspectives the reasons for organizational ineffectiveness and remedies are presented. There is little doubt that pressure for nurses to perform is escalating as healthcare institutions attempt to improve the quality of service through restructuring and change, which leads to greater job dissatisfaction, higher turnover, lower morale and increased industrial actions of nurses. An integrated approach to organizational learning is arguably important for the effective management of nurses during periods of transition.",2001-09,26/11/2018 12:53,14/04/2020 08:34,,196-199,,3,8,,Nurs Inq,,,,,,,,eng,,,,,,,PMID: 11882219,,,,"Humans; Learning; *Interprofessional Relations; Models, Educational; Organizational Culture; *Systems Theory; Organizational Innovation; Professional Competence/standards; Total Quality Management/*organization & administration; 00; Nurse Administrators/education/*organization & administration; Nursing, Supervisory/*organization & administration; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, CIW6G4FV,journalArticle,2002,"Mason, J.; Axon, A. T. R.; Forman, D.; Duffett, S.; Drummond, M.; Crocombe, W.; Feltbower, R.; Mason, S.; Brown, J.; Moayyedi, P.",The cost-effectiveness of population Helicobacter pylori screening and treatment: a Markov model using economic data from a randomized controlled trial.,Alimentary pharmacology & therapeutics,,0269-2813 0269-2813,,,"BACKGROUND: Economic models have suggested that population Helicobacter pylori screening and treatment may be a cost-effective method of reducing mortality from gastric cancer. These models are conservative as they do not consider that the programme may reduce health service peptic ulcer and other dyspepsia costs. We have evaluated the economic impact of population H. pylori screening and treatment over 2 years in a randomized controlled trial and have incorporated the results into an economic model exploring the impact of H. pylori eradication on peptic ulcer disease and gastric cancer. METHODS: Subjects between the ages of 40 and 49 years were randomly invited to attend their local primary care centre. H. pylori status was evaluated by (13)C-urea breath test and infected individuals were randomized to receive omeprazole, 20 mg b.d., clarithromycin, 250 mg b.d., and tinidazole, 500 mg b.d., for 7 days or identical placebos. Economic data on health service costs for dyspepsia were obtained from a primary care note review for the 2 years following randomization. These data were incorporated into a Markov model comparing population H. pylori screening and treatment with no intervention. RESULTS: A total of 2329 of 8407 subjects were H. pylori positive: 1161 were randomized to receive eradication therapy and 1163 to receive placebo. The cost difference favoured the intervention group 2 years after randomization, but this did not reach statistical significance (11.42 ponds sterling per subject cost saving; 95% confidence interval, 30.04 ponds sterling to -7.19 pounds sterling; P=0.23). Analysis by gender suggested a statistically significant dyspepsia cost saving in men (27.17 ponds sterling per subject; 95% confidence interval, 50.01 pounds sterling to 4.32 pounds sterling; P=0.02), with no benefit in women (-4.46 per subject; 95% confidence interval, -33.85 pounds sterling to 24.93 pounds sterling). Modelling of these data suggested that population H. pylori screening and treatment for 1,000,000 45-year-olds would save over 6,000,000 pounds sterling and 1300 years of life. The programme would cost 14, 200 pounds sterling per life year saved if the health service dyspepsia cost savings were the lower limit of the 95% confidence intervals and H. pylori eradication had only a 10% efficacy in reducing mortality from distal gastric cancer and peptic ulcer disease. CONCLUSIONS: Modelling suggests that population H. pylori screening and treatment are likely to be cost-effective and could be the first cost-neutral screening programme. This provides a further mandate for clinical trials to evaluate the efficacy of population H. pylori screening and treatment in preventing mortality from gastric cancer and peptic ulcer disease.",2002-03,26/11/2018 12:53,14/04/2020 08:34,,559-568,,3,16,,Aliment Pharmacol Ther,,,,,,,,eng,,,,,,,PMID: 11876711,,,,Humans; Randomized Controlled Trials as Topic; Adult; Female; Male; Middle Aged; Risk Factors; *Cost-Benefit Analysis; *Markov Chains; *Health Care Costs; Mass Screening/*economics; Anti-Bacterial Agents/economics/therapeutic use; Helicobacter pylori/*isolation & purification; Clarithromycin/economics/therapeutic use; Dyspepsia/complications/diagnosis/drug therapy/microbiology; Helicobacter Infections/complications/*diagnosis/*drug therapy/microbiology; Omeprazole/economics/therapeutic use; Peptic Ulcer/complications/diagnosis/drug therapy/microbiology; Tinidazole/economics/therapeutic use; 00; 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, P4H6NFJN,journalArticle,2002,"Nuijten, Mark J. C.; Hutton, John",Cost-effectiveness analysis of interferon beta in multiple sclerosis: a Markov process analysis.,Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research,,1098-3015 1098-3015,10.1046/j.1524-4733.2002.51052.x,,"OBJECTIVE: The objective of this study was to examine the cost-effectiveness of preventive treatment with interferon beta (IFNB) versus no preventive treatment in patients with multiple sclerosis. METHODS: The setting for this study was the United Kingdom. A lifetime Markov process model was constructed to model the average quality-adjusted life years (QALYs) and the costs of both treatment strategies. Data for the construction of the model came from published literature, including large multicenter randomized clinical trials in relapsing-remitting and secondary progressive multiple sclerosis. Costs were obtained from published sources. RESULTS: The results of the baseline analysis from the National Health Service (NHS) perspective showed that the use of interferon beta as preventive treatment for MS increased the total average discounted cost from 51,214 Pounds to 221,436 Pounds per patient. The undiscounted effectiveness increased from 24.9 QALYs to 28.2 QALYs, resulting in an incremental cost-effectiveness ratio of 51,582 Pounds per QALY. Sensitivity analyses showed the robustness of this model for other interferons. CONCLUSION: The study showed that preventive treatment with interferon beta in patients with multiple sclerosis may not be fully justified from a health-economic perspective, although interferon beta is associated with an improved effectiveness compared with no preventive treatment.",2002-02,26/11/2018 12:53,14/04/2020 08:35,,44-54,,1,5,,Value Health,,,,,,,,eng,,,,,,,PMID: 11873383,,,,"Humans; Cost-Benefit Analysis; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Adult; Female; Male; Middle Aged; *Markov Chains; Costs and Cost Analysis; Age Factors; Sex Factors; Adjuvants, Immunologic/administration & dosage/*economics/*therapeutic use; Interferon-beta/administration & dosage/*economics/*therapeutic use; Multicenter Studies as Topic; Multiple Sclerosis/*drug therapy/*economics/epidemiology; 00; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, I8TP4AHC,journalArticle,2002,"Leon, Andrew C.; Walkup, James T.; Portera, Laura",Assessment and treatment of depression in disability claimants: a cost-benefit simulation study.,The Journal of nervous and mental disease,,0022-3018 0022-3018,,,"The economic burden of depression includes direct costs of treatment, as well as absenteeism and reduced productivity. In this study, we consider the costs and benefits of an intervention to assess and treat depressive symptoms in long-term disability claimants with nonpsychiatric medical illnesses. Cost-benefit simulations were conducted using data from a study sample of long-term disability claimants (N = 1229) and estimates of both the costs of treatment of depressive symptoms and the savings in claims payments for those who return to work as a result of treatment. We show that the savings that stem from returning a very few claimants to work can offset the assumed cost of a comprehensive program for the assessment of depressive symptoms in all claimants and intensive treatment of those with depressive symptoms. The economic and public health benefits both point toward the value of such an intervention for disability claimants.",2002-01,26/11/2018 12:53,14/04/2020 08:34,,03-Sep,,1,190,,J Nerv Ment Dis,,,,,,,,eng,,,,,,,PMID: 11838028,,,,"Humans; Cost-Benefit Analysis; Female; Male; Middle Aged; Comorbidity; Health Care Costs/*statistics & numerical data; Cost of Illness; Health Expenditures/statistics & numerical data; Depressive Disorder/diagnosis/economics/*therapy; Insurance, Disability/*economics/statistics & numerical data; Karnofsky Performance Status/statistics & numerical data; 140",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VBYNC2Y9,journalArticle,2001,"Higgins, G.; Athey, B.; Bassingthwaighte, J.; Burgess, J.; Champion, H.; Cleary, K.; Dev, P.; Duncan, J.; Hopmeier, M.; Jenkins, D.; Johnson, C.; Kelly, H.; Leitch, R.; Lorensen, W.; Metaxas, D.; Spitzer, V.; Vaidehi, N.; Vosburgh, K.; Winslow, R.","Final report of the meeting ""modeling & simulation in medicine: towards an integrated framework"". July 20-21, 2000, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, USA.",Computer aided surgery : official journal of the International Society for Computer Aided Surgery,,1092-9088 1092-9088,10.1002/igs.1008,,"Researchers met at the National Library of Medicine on July 20–21, 2000, to brainstorm about the next stage in the development of a “functional” visible human. This meeting, called “Modeling & Simulation in Medicine: Towards an Integrated Framework,” was organized to review the current state of computer-based modeling in medicine, identify critical “next steps” for technical resource development, and create a vision for building useful and functional computer models of human biology.",2001,26/11/2018 12:53,14/04/2020 08:34,,32-39,,1,6,,Comput Aided Surg,,,,,,,,eng,,,,,,,PMID: 11335957,,,,"Humans; *Computer Simulation; *User-Computer Interface; 1; *Anatomy, Cross-Sectional; 11; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WIB8NHU2,journalArticle,2001,"Dean, B.; Barber, N.; van Ackere, A.; Gallivan, S.",Can simulation be used to reduce errors in health care delivery? The hospital drug distribution system.,Journal of health services research & policy,,1355-8196 1355-8196,10.1258/1355819011927170,,"OBJECTIVES: To construct a simulation model of the hospital drug distribution system, to evaluate the effects of different changes to the system on unavailability-related medication administration errors (U-MAEs), to test the most promising system in a controlled trial and to explore the model's validity. METHODS: A discrete-event simulation model of the drug distribution system was constructed, using data collected on a vascular surgery ward and a renal medicine ward as model inputs. The model's output was the U-MAE rate. The model was used to explore the effects on U-MAEs of different changes to the system. One of the changes predicted to reduce U-MAEs, a patients' own drugs scheme, was introduced on each study ward; U-MAE rates were measured using observations before and after its introduction and compared with those predicted by the model. RESULTS: The model predicted that the introduction of a patients' own drugs system would reduce unavailability-related errors on each ward; in practice, there was a slight decrease on the medical ward but an increase on the surgical ward. Reasons for these findings were explored and four contributing factors identified. Three of these related to failure to follow hospital procedures, the fourth to an issue for which no policy existed. If these factors had been taken into account, the error rates predicted by the model would have been similar to those observed. CONCLUSIONS: Simulation modelling is a potentially useful approach to the study of U-MAEs, although care must be taken to ensure that such models reflect actual practice rather than stated policy.",2001-01,26/11/2018 12:53,14/04/2020 08:34,,32-37,,1,6,,J Health Serv Res Policy,,,,,,,,eng,,,,,,,PMID: 11219358,,,,"Humans; *Computer Simulation; *Models, Organizational; Research Design; United Kingdom; Data Interpretation, Statistical; Health Services Research/methods; Discrete event simulation; 1; Medication Errors/*prevention & control/statistics & numerical data; Hospital Bed Capacity, 500 and over; Hospitals, Teaching; Medication Systems, Hospital/*organization & administration/standards; Patients' Rooms/*organization & administration; 320; Discrete Event",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, D2C4EE4Y,journalArticle,2001,"Campbell, H.; Karnon, J.; Dowie, R.",Cost analysis of a hospital-at-home initiative using discrete event simulation.,Journal of health services research & policy,,1355-8196 1355-8196,10.1258/1355819011927152,,"OBJECTIVES: To examine whether, from a National Health Service (NHS) and local authority social services' viewpoint, a hospital-at-home service was cost saving compared with conventional inpatient care. METHODS: The subjects of this part-retrospective and part-prospective cost analysis were 51 elderly medical and orthopaedic surgical patients assessed at Hillingdon Hospital, West London, as being suitable for hospital-at-home care. Thirty patients received hospital-at-home care, provided for up to 14 days, while 21 patients remained in hospital and received standard inpatient care. All direct costs to the NHS hospital, community health services' provider and social services' department during the initial episode of care and the three months after discharge were collected for each group of patients. Costs and clinical event data were entered in a discrete event simulation model which generated baseline results. Uncertainty surrounding the model's parameters was explored using sensitivity analysis. RESULTS: The baseline simulation performed with 1000 patients in each group showed the mean cost per patient for hospital-at-home care and three-month follow-up to be around three-fifths the mean cost per patient of inpatient care and follow-up. Most of the excess cost in the inpatient group was attributable to the initial period of hospitalisation. Under all assumptions used in the sensitivity analysis, the hospital-at-home service was less costly. CONCLUSIONS: For elderly patients assessed as needing no more than 14 days of hospital care, hospital-at-home care is cost saving to health and social care agencies when compared with conventional inpatient care.",2001-01,26/11/2018 12:53,14/04/2020 08:34,,14-22,,1,6,,J Health Serv Res Policy,,,,,,,,eng,,,,,,,PMID: 11219355,,,,"Humans; Middle Aged; Aged; Retrospective Studies; Computer Simulation; Health Care Costs/*statistics & numerical data; Models, Econometric; Prospective Studies; Health Services Research/methods; discrete event simulation; 1; London; Hospital Costs/statistics & numerical data; Home Care Services, Hospital-Based/*economics; Hospitalization/*economics; Hospitals, Public/economics; Orthopedics/economics; State Medicine/economics; Subacute Care/*economics; 310",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, AZ5PIWER,journalArticle,2001,"Bareford, C. G.",Community as client: environmental issues in the real world. A SimCity computer simulation.,Computers in nursing,,0736-8593 0736-8593,,,"The ability to think critically has become a crucial part of professional practice and education. SimCity, a popular computer simulation game, provides an opportunity to practice community assessment and interventions using a systems approach. SimCity is an interactive computer simulation game in which the player takes an active part in community planning. SimCity is supported on either a Windows 95/98 or a Macintosh platform and is available on CD-ROM at retail stores or at www.simcity.com. Students complete a tutorial and then apply a selected scenario in SimCity. Scenarios consist of hypothetical communities that have varying types and degrees of environmental problems, e.g., traffic, crime, nuclear meltdown, flooding, fire, and earthquakes. In problem solving with the simulated scenarios, students (a) identify systems and subsystems within the community that are critical factors impacting the environmental health of the community, (b) create changes in the systems and subsystems in an effort to solve the environmental health problem, and (c) evaluate the effectiveness of interventions based on the game score, demographic and fiscal data, and amount of community support. Because the consequences of planned intervention are part of the simulation, nursing students are able to develop critical-thinking skills. The simulation provides essential content in community planning in an interesting and interactive format.",2001-02,26/11/2018 12:53,14/04/2020 08:34,,Nov-16,,1,19,,Comput Nurs,,,,,,,,eng,,,,,,,PMID: 11210449,,,,Humans; Curriculum; *Computer Simulation; Community Health Nursing/*education; User-Computer Interface; 00; *Video Games; *Community Health Planning; 110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, FSBEJ3QM,journalArticle,2000,"Eisenberg, J. M.",Continuing education meets the learning organization: the challenge of a systems approach to patient safety.,The Journal of continuing education in the health professions,,0894-1912 0894-1912,10.1002/chp.1340200403,,"Since the release of the report of the Institute of Medicine on medical errors and patient safety in November 1999, health policy makers and health care leaders in several nations have sought solutions that will improve the safety of health care. This attention to patient safety has high-lighted the importance of a learning approach and a systems approach to quality measurement and improvement. Balanced with the need for public disclosure of performance, confidential reporting with feedback is one of the prime ways that nations such as the United States, Canada, the United Kingdom, and Australia have approached this challenge. In the United States, the Quality Interagency Coordination Task Force has convened federal agencies that are involved in health care quality improvement for a coordinated initiative. Based on an investment in a strong research foundation in health care quality measurement and improvement, there are eight key lessons for continuing education if it is to parlay the interest in patient safety into enhanced continuing education and quality improvement in learning health care systems. The themes for these lessons are (1) informatics for information, (2) guidelines as learning tools, (3) learning from opinion leaders, (4) learning from the patient, (5) decision support systems, (6) the team learning together, (7) learning organizations, and (8) just-in-time and point-of-care delivery.",2000,26/11/2018 12:53,14/04/2020 08:34,,197-207,,4,20,,J Contin Educ Health Prof,,,,,,,,eng,,,,,,,PMID: 11201059,,,,"Humans; United States; Systems Analysis; *Safety Management; Medical Errors/*prevention & control; *Learning; Organizational Innovation; Total Quality Management/*organization & administration; 00; *Organizational Culture; *Education, Continuing; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BYQ6HJLE,journalArticle,2000,"Groothuis, S.; van Merode, G. G.",Discrete event simulation in the health policy and management program.,Methods of information in medicine,,0026-1270 0026-1270,,,"Students in Health Policy and Management at the Faculty of Health Sciences of Maastricht University must learn to analyze and design workflow processes in health care. To attain this, a discrete event simulation training, using MedModel is used. This paper describes the training in two consecutive years. In both years the training was evaluated systematically. The evaluation results demonstrate that the simulation training increased the students' knowledge about analyzing and designing workflow processes in healthcare. Students considered the training as a very important part of their program.",2000-12,26/11/2018 12:53,14/04/2020 08:34,,339-342,,04-May,39,,Methods Inf Med,,,,,,,,eng,,,,,,,PMID: 11191703,,,,"Humans; Netherlands; Program Evaluation; *Computer Simulation; *Models, Educational; Educational Measurement; Education, Professional/*methods; *Problem-Based Learning; 1; *Health Services Administration; *Task Performance and Analysis; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, V2FJ4JBV,journalArticle,2001,"Schlosser, W.; Ebel, E.",Use of a Markov-chain Monte Carlo model to evaluate the time value of historical testing information in animal populations.,Preventive veterinary medicine,,0167-5877 0167-5877,,,"Quantitative risk assessments are now required to support many regulatory decisions involving infectious diseases of animals. Current methods, however, do not consider the relative values of historical and recent data. A Markov-chain model can use specific disease characteristics to estimate the present value of disease information collected in the past. Uncertainty about the disease characteristics and variability among animals and herds can be accounted for with Monte Carlo simulation modeling. This results in a transparent method of valuing historical testing information for use in risk assessments. We constructed such a model to value historical testing information in a more-transparent and -reproducible manner. Applications for this method include trade, food safety, and domestic animal-health regulations.",16/02/2001,26/11/2018 12:53,14/04/2020 08:35,,167-175,,3,48,,Prev Vet Med,,,,,,,,eng,,,,,,,PMID: 11182461,,,,"Humans; Risk Assessment; *Markov Chains; Public Health; Animals; *Monte Carlo Method; Public Policy; 00; Animal Diseases/*transmission; Animals, Domestic; Food Contamination; Veterinary Medicine; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 7K2IBFNT,journalArticle,2001,"Revicki, D. A.; Gold, K.; Buckman, D.; Chan, K.; Kallich, J. D.; Woolley, J. M.",Imputing physical health status scores missing owing to mortality: results of a simulation comparing multiple techniques.,Medical care,,0025-7079 0025-7079,,,"BACKGROUND: Having missing data complicates the statistical analysis of health-related quality-of-life (HRQOL) data and, depending on the extent and nature of missing data, can introduce significant bias in treatment comparisons. OBJECTIVE: We evaluated the bias associated with 4 different imputation methods for estimating physical health status (PHS) scores missing as a result of mortality. METHODS: A simulation study was conducted in which we systematically varied mortality rates from 0% to 30% and change in PHS scores from -20 to 20 on a 100-point scale for a 2-group clinical trial with follow-up over 18 months. The 4 imputation methods were last value carried forward (LVCF), arbitrary substitution (ARBSUB), empirical Bayes (BAYES), and within-subject modeling (WSMOD). Pseudo-root mean square residuals (RMSRs) and differences between true and estimated slopes were used to evaluate how well the imputation methods reproduced the true characteristics of the simulated population data. RESULTS: ARBSUB and BAYES methods have the smallest RMSRs compared with LVCF and WSMOD across all mortality rates. As the rate of missing data resulting from mortality increased, all imputation techniques deviated more from population data. The BAYES technique was best at reproducing group slopes in cases with differential mortality rates or when mortality rates exceeded 15%. WSMOD and LVCF significantly underestimated changes in PHS. CONCLUSIONS: The different imputation methods produced comparable results when there were few missing data. The BAYES approach most closely estimated true population differences and change in PHS regardless of missing data rates. These findings are limited to physical health and functioning measures.",2001-01,26/11/2018 12:53,14/04/2020 08:35,,61-71,,1,39,,Med Care,,,,,,,,eng,,,,,,,PMID: 11176544,,,,"Humans; *Quality-Adjusted Life Years; *Models, Statistical; Bayes Theorem; Computer Simulation; Data Interpretation, Statistical; *Health Status Indicators; Bias; Analysis of Variance; *Mortality; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, BS5FY8CI,journalArticle,2000,"Glance, L. G.; Osler, T. M.; Papadakos, P.",Effect of mortality rate on the performance of the Acute Physiology and Chronic Health Evaluation II: a simulation study.,Critical care medicine,,0090-3493 0090-3493,,,"OBJECTIVE: To evaluate the impact of case mix variation on the performance of the Acute Physiology and Chronic Health Evaluation (APACHE) II using measures of calibration and discrimination. DESIGN: APACHE II data were collected prospectively at the surgical intensive care unit of the University of Vermont on all adult admissions over an 8-yr period (excluding cardiac surgical patients, burn patients, and patients < 16 yrs of age). The original case mix was systematically varied to create 2,000 different case mixes ranging in mortality between 5% and 18% using a computer-intensive resampling algorithm. The area under the receiver operating characteristic curve and the Hosmer-Lemeshow C statistic were derived for each of the simulated case mixes with bootstrapping. SETTING: The surgical intensive care unit at a 450-bed teaching hospital. PATIENTS: A group of 6,806 adult surgical patients excluding cardiac surgical patients and burn patients. MEASUREMENTS AND RESULTS: Simulated data sets were created from a database of patients treated at a single institution to test the hypothesis that the performance of APACHE II is stable across a clinically reasonable range of mortality rates. The discrimination and calibration of APACHE II varied with case mix. CONCLUSION: The discrimination of APACHE II is not independent of case mix. However, the variability of the Hosmer-Lemeshow statistic as a function of the case mix may simply reflect the limitations of this goodness of fit statistic to assess model calibration. Because the discrimination of APACHE II is a function of case mix, caution should be exercised when using APACHE II-based adjusted mortality rates to compare intensive care units with widely divergent case mixes.",2000-10,26/11/2018 12:53,14/04/2020 08:34,,3424-3428,,10,28,,Crit Care Med,,,,,,,,eng,,,,,,,PMID: 11057796,,,,"Humans; Outcome Assessment (Health Care); Adult; Risk Factors; Prognosis; Algorithms; Linear Models; Prospective Studies; Hospitals, University; Predictive Value of Tests; Survival Analysis; ROC Curve; Discriminant Analysis; Calibration; *APACHE; *Hospital Mortality; *Intensive Care Units/statistics & numerical data; Diagnosis-Related Groups/*classification/statistics & numerical data; Vermont/epidemiology; Review",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, G2RC7AKF,journalArticle,2000,"Buttner, A.; Randerath, W.; Ruhle, K. H.","[The driving simulation test ""carsim"" for assessing vigilance. Effect of driving practice and other factors in health subjects and in patients with sleep apnea syndrome].","Pneumologie (Stuttgart, Germany)",,0934-8387 0934-8387,10.1055/s-2000-6954,,"Among other factors, obstructive sleep apnoea (OSAS) patients suffer from impaired continuous attention. For registration and objectification as well as observation of the course of therapy, driving simulation programmes are particularly suitable. ""Carsim"", a driving simulation newly developed by us, simulates a bendy road via a screen where a vehicle is supposed to be kept on the right lane by operating a steering wheel. Apart from examination of quality criteria (objectivity, reliability, validity) and establishment of standard values, the influence of significant variables (age, gender, school education, profession, duration of disorder, AHI, BMI, visual and motor functionability, driving license, driving experience, Epworth score, accident frequency) on patients and healthy controls requires to be evaluated. For this purpose, 100 healthy controls, 200 OSAS patients and 30 patients under nCPAP were analysed. In healthy persons and patients under nCPAP, driving experience had no impact on the driving simulation results. OSAS patients with no driving license and no driving experience achieved lower marks for tracking than patients with driving license or a lot of driving experience (no driving license: x = 8058 +/- 10,878 track deviations; with driving licence: x = 2111 +/- 6564 track deviations; p < .001). According to our findings, untreated OSAS severely interferes with patients' attention capacity as well as their coping strategies.",2000-08,26/11/2018 12:53,14/04/2020 08:34,,338-344,,8,54,,Pneumologie,,,,,,,,ger,,,,,,,PMID: 11008476,,,,"Humans; Female; Male; 00; Reference Values; *Arousal; *Attention; *Automobile Driving; Motor Activity; Sleep Apnea, Obstructive/diagnosis/*physiopathology/psychology; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, U5EU47N7,journalArticle,2000,"Ramsey, S. D.; McIntosh, M.; Etzioni, R.; Urban, N.",Simulation modeling of outcomes and cost effectiveness.,Hematology/oncology clinics of North America,,0889-8588 0889-8588,,,"Modeling will continue to be used to address important issues in clinical practice and health policy issues that have not been adequately studied with high-quality clinical trials. The apparent ad hoc nature of models belies the methodologic rigor that is applied to create the best models in cancer prevention and care. Models have progressed from simple decision trees to extremely complex microsimulation analyses, yet all are built using a logical process based on objective evaluation of the path between intervention and outcome. The best modelers take great care to justify both the structure and content of the model and then test their assumptions using a comprehensive process of sensitivity analysis and model validation. Like clinical trials, models sometimes produce results that are later found to be invalid as other data become available. When weighing the value of models in health care decision making, it is reasonable to consider the alternatives. In the absence of data, clinical policy decisions are often based on the recommendations of expert opinion panels or on poorly defined notions of the standard of care or medical necessity. Because such decision making rarely entails the rigorous process of data collection, synthesis, and testing that is the core of well-conducted modeling, it is usually not possible for external audiences to examine the assumptions and data that were used to derive the decisions. One of the modeler's most challenging tasks is to make the structure and content of the model transparent to the intended audience. The purpose of this article is to clarify the process of modeling, so that readers of models are more knowledgeable about their uses, strengths, and limitations.",2000-08,26/11/2018 12:53,14/04/2020 08:35,,925-938,,4,14,,Hematol Oncol Clin North Am,,,,,,,,eng,,,,,,,PMID: 10949781,,,,"Humans; Reproducibility of Results; *Cost-Benefit Analysis; Markov Chains; *Computer Simulation; *Models, Theoretical; Costs and Cost Analysis; Probability; Decision Theory; *Outcome Assessment (Health Care)/*methods; Neoplasms/economics/therapy; 00; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, TTV296IV,journalArticle,2000,"Keepnews, D.",A systems approach to health care errors.,The American journal of nursing,,0002-936X 0002-936X,,,,2000-06,26/11/2018 12:53,14/04/2020 08:34,,77-78,,6,100,,Am J Nurs,,,,,,,,eng,,,,,,,PMID: 10892332,,,,"Delivery of Health Care/*organization & administration; Humans; *Quality of Health Care; United States; *Safety; National Academies of Science, Engineering, and Medicine (U.S.) Health and Medicine Division; 1; Mandatory Reporting; *Medical Errors/prevention & control; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, H7U23L2P,journalArticle,2000,"Caro, J. J.",Disease-simulation models and health care decisions.,CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne,,0820-3946 0820-3946,,,,04/04/2000,26/11/2018 12:53,14/04/2020 08:34,,1001-1002,,7,162,,CMAJ,,,,,,,,eng,,,,,,,PMID: 10763398 PMCID: PMC1232303,,,,"Humans; Health Policy; *Models, Theoretical; Policy Making; *Decision Making; *Evidence-Based Medicine; 1; Delivery of Health Care/*trends; 100",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, MSB9QC7H,journalArticle,2000,"Feussner, J. R.; Demakis, J. G.",Does health systems thinking guide health services actions?,Health services research,,0017-9124 0017-9124,,,"The theme of the current issue of thejournal reflects research that represents health systems thinking: variations in patterns of care, and outcomes of care. The theme of variation in health services delivery is a familiar one for health services researchers. In addition, outcomes include health systems efficiencies, population-specific results, and improvement in the health or vital status of patients. Given these recurring priorities for health services research, how well do these several manuscripts reflect a systems approach, and what are some of the key components of such an approach.",2000-03,26/11/2018 12:53,14/04/2020 08:34,,1409-1412,,7,34,,Health Serv Res,,,,,,,,eng,,,,,,,PMID: 10737444 PMCID: PMC1975664,,,,"Delivery of Health Care/*organization & administration; Humans; Evidence-Based Medicine; *Systems Analysis; Research Design; Data Collection; Feedback; 1; Health Services Research/*organization & administration; *Philosophy, Medical; Outcome Assessment (Health Care)/*organization & administration; Practice Patterns, Physicians'/*organization & administration; 110",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, WFSTH3UE,journalArticle,2006,"Rutten-van Molken, M.",Economic Modeling in Chronic Obstructive Pulmonary Disease,Proceedings of the American Thoracic Society,,1546-3222,10.1513/pats.200603-095SS,http://pats.atsjournals.org/cgi/doi/10.1513/pats.200603-095SS,"Calculating the cost-effectiveness of interventions is an important step in accurately assessing the health and financial burdens of a disease. Although clinical trials that include cost data can be used to compare the cost-effectiveness of specific interventions, they only deal with outcomes within the time frame of the trial. Health economic models can synthesize epidemiologic, clinical, economic, and quality-of-life data from many different sources and extrapolate results to a point many years in the future. The models generally compare interventions with respect to the costs per life-year gained or per quality-adjusted life-year gained. The use of health economic models to assess the economic burden of chronic obstructive pulmonary disease (COPD) and the value of interventions is growing, and will continue to do so as the burden of the disease is better appreciated. Several COPD disease-state models have been described; each uses a consistent definition of COPD severity that is based on FEV1% predicted, but the models differ in the allowed transitions, disease progression estimates, utility weights, and costs. This article reviews COPD health economic models and discusses the importance of survival benefits and utilities (health state valuations) for COPD in economic models.",01/09/2006,10/05/2019 09:12,14/04/2020 08:34,10/05/2019 09:12,630-634,,7,3,,,,,,,,,,en,,,,,Crossref,,,,,,SB,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4ZEYYS3N,journalArticle,2005,"Hoogendoorn, M.",A dynamic population model of disease progression in COPD,European Respiratory Journal,,"0903-1936, 1399-3003",10.1183/09031936.05.00122004,http://erj.ersjournals.com/cgi/doi/10.1183/09031936.05.00122004,,01/08/2005,10/05/2019 09:12,14/04/2020 08:34,10/05/2019 09:12,223-233,,2,26,,,,,,,,,,en,,,,,Crossref,,,,,,SB,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, GS94YW6W,book,2008,,"2008 Winter Simuation Conference: (WSC 2008) ; Miami, Florida, USA, 7 - 10 December 2008 ; [incorporate ... the MASM (Modeling and Analysis for Semiconductor Manufacturing) Conference]",,978-1-4244-2708-6 978-1-4244-2707-9,,,,,2008,10/05/2019 09:27,14/04/2020 08:34,,,,,,,,2008 Winter Simuation Conference,,,,,IEEE,"Piscataway, NJ",eng,,,,,Gemeinsamer Bibliotheksverbund ISBN,,,Kongr.-Thema: Global gateway to discovery. - Auf d. CD auch bez. als: WSC'08,,,100,,"Mason, Scott J.; American Statistical Association; Association for Computing Machinery; IEEE Systems, Man, and Cybernetics Society",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8RGLFFNG,conferencePaper,2009,"Aleman, Dionne M.; Wibisono, Theodorus G.; Schwartz, Brian",Accounting for individual behaviors in a pandemic disease spread model,Proceedings of the 2009 Winter Simulation Conference (WSC),978-1-4244-5770-0,,10.1109/WSC.2009.5429727,http://ieeexplore.ieee.org/document/5429727/,,2009-12,10/05/2019 09:34,14/04/2020 08:34,10/05/2019 09:34,1977-1985,,,,,,,,,,,IEEE,"Austin, TX, USA",,,,,,Crossref,,,,,,SB,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2009 Winter Simulation Conference - (WSC 2009),,,,,,,,,,,,,,, 5IMNMHJX,conferencePaper,2009,"Koppenhaver, Robert T.; Schaefer, Andrew; Braithwaite, R. Scott; Roberts, Mark",A simulation model of HIV treatment under drug scarcity constraints,Proceedings of the 2009 Winter Simulation Conference (WSC),978-1-4244-5770-0,,10.1109/WSC.2009.5429643,http://ieeexplore.ieee.org/document/5429643/,,2009-12,10/05/2019 10:09,14/04/2020 08:34,10/05/2019 10:09,2090-2095,,,,,,,,,,,IEEE,"Austin, TX, USA",,,,,,Crossref,,,,,,SB,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2009 Winter Simulation Conference - (WSC 2009),,,,,,,,,,,,,,, 3QU2Y8TQ,journalArticle,2007,"Dev, Parvati; Heinrichs, W. LeRoy; Youngblood, Patricia; Kung, Sean; Cheng, Robert; Kusumoto, Laura; Hendrick, Arnold",Virtual patient model for multi-person virtual medical environments,AMIA ... Annual Symposium proceedings. AMIA Symposium,,1942-597X,,,"We describe the architecture of a virtual patient model, the Virtual ED Patient, for scenarios in emergency medicine. The model is rule-based, and uses four vital signs as a representation of its state. The model is used in a multi-person learning environment based on online gaming technology. The efficacy of the model and the Virtual ED learning environment is evaluated in a study where advanced medical students and first year residents manage six trauma cases. Pre and post-test performance results show significant learning, with results comparable to those obtained in human manikin simulators. Some future directions for development of the model are also presented.",11/10/2007,10/05/2019 10:10,14/04/2020 08:34,,181-185,,,,,AMIA Annu Symp Proc,,,,,,,,eng,,,,,PubMed,,PMID: 18693822 PMCID: PMC2655782,,,http://www.ncbi.nlm.nih.gov/pubmed/18693822,SB,Humans; Computer Simulation; Patient Simulation; User-Computer Interface; Emergency Medicine,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, V3NHY9ZD,conferencePaper,2004,"Takakuwa, S.; Shiozaki, H.",Functional Analysis for Operating Emergency Department of a General Hospital,"Proceedings of the 2004 Winter Simulation Conference, 2004.",978-0-7803-8786-7,,10.1109/WSC.2004.1371562,http://ieeexplore.ieee.org/document/1371562/,"An entire emergency department of a general hospital is simulated to examine patient flows. First, times needed for both outpatients and patients arriving via ambulance to be processed in the emergency department are examined. A special-purpose data-generator is designed and developed to create experimental data for executing a simulation. It is found that the patients spend the longer part of their time waiting, depending on the number of patients to be processed. In addition, it is found that the waiting time for available emergency-treatment beds, doctors, drips, and stretchers accounts for the major part of all the waiting time in the emergency department. A stepwise procedure of operations planning is proposed to minimize the patient waiting times, and numerical examples are shown to illustrate the procedure.",2004,10/05/2019 10:11,14/04/2020 08:34,10/05/2019 10:11,917-925,,,2,,,,,,,,IEEE,"Washington, D.C.",,,,,,Crossref,,,,,,SB,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2004 Winter Simulation Conference, 2004.",,,,,,,,,,,,,,, DE7AUPHL,journalArticle,2008,"Jensen, Kirk; Crane, Jody",Improving patient flow in the emergency department,Healthcare Financial Management: Journal of the Healthcare Financial Management Association,,0735-0732,,,"To improve patient flow in the ED, hospitals should: Establish a measure of patient demand by hour, and design a system to handle it. Appropriately capacitate triage processes and systems. Use a system for patient segmentation and establish distinct processes for different patient segments. Consider using team triage, and examine current triage protocols. Devise a method of tracking patients and results. Field a willing staff with a burning platform.",2008-11,10/05/2019 10:12,14/04/2020 08:34,,"104-106, 108",,11,62,,Healthc Financ Manage,,,,,,,,eng,,,,,PubMed,,PMID: 18990843,,; ,http://www.ncbi.nlm.nih.gov/pubmed/18990843; http://www.ncbi.nlm.nih.gov/pubmed/18990843,"Humans; United States; Emergency Service, Hospital; Process Assessment (Health Care); Health Services Needs and Demand; Patient Care Planning; Planning Techniques; Organizational Innovation; Needs Assessment; Time and Motion Studies; Triage; Poisson Distribution; Periodicity; Review",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 582KKZYY,conferencePaper,2004,"Ferrin, D.M.; Miller, M.J.; Wininger, S.; Neuendorf, M.S.",Analyzing Incentives and Scheduling in a Major Metropolitan Hospital Operating Room through Simulation,"Proceedings of the 2004 Winter Simulation Conference, 2004.",978-0-7803-8786-7,,10.1109/WSC.2004.1371558,http://ieeexplore.ieee.org/document/1371558/,This paper discusses the application of simulation to analyze the value proposition and construction of an incentive program in an operating room (OR) environment. The model was further used to evaluate operational changes including scheduling processes within the OR and utilization rates in areas such as post anesthesia care unit (PACU) and the ambulatory surgery department (ASD). Lessons learned are presented on developing multiple simulation models from one application as well as issues regarding model transition to a client.,2004,10/05/2019 10:13,14/04/2020 08:34,10/05/2019 10:13,889-894,,,2,,,,,,,,IEEE,"Washington, D.C.",,,,,,Crossref,,,,,,SB,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"2004 Winter Simulation Conference, 2004.",,,,,,,,,,,,,,, 4T495LNV,journalArticle,2007,"Vasilakis, C; Sobolev, B G; Kuramoto, L; Levy, A R",A simulation study of scheduling clinic appointments in surgical care: individual surgeon versus pooled lists,Journal of the Operational Research Society,,"0160-5682, 1476-9360",10.1057/palgrave.jors.2602235,https://www.tandfonline.com/doi/full/10.1057/palgrave.jors.2602235,"The purpose of this paper is to compare two methods of scheduling outpatient clinic appointments in the setting where the availability of surgeons for appointments depends on other clinical activities. We used discrete-event simulation to evaluate the likely impact of the scheduling methods on the number of patients waiting for appointments, and the times to appointment and to surgery. The progression of individual patients in a surgical service was modelled as a series of updates in patient records in reaction to events generated by care delivery processes in an asynchronous fashion. We used the Statecharts visual formalism to define states and transitions within each care delivery process, based on detailed functional and behavioural specifications. Our results suggest that pooling referrals, so that clinic appointments are scheduled with the first available surgeon, has a differential impact on different segments of patient flow and across surgical priority groups.",2007-02,10/05/2019 10:14,14/04/2020 08:34,10/05/2019 10:14,202-211,,2,58,,,A simulation study of scheduling clinic appointments in surgical care,,,,,,,en,,,,,Crossref,,,,,,SB,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, G36YPX27,journalArticle,2005,"Griffiths, J D; Price-Lloyd, N; Smithies, M; Williams, J E",Modelling the requirement for supplementary nurses in an intensive care unit,Journal of the Operational Research Society,,"0160-5682, 1476-9360",10.1057/palgrave.jors.2601882,https://www.tandfonline.com/doi/full/10.1057/palgrave.jors.2601882,,2005-02,10/05/2019 10:15,14/04/2020 08:34,10/05/2019 10:15,126-133,,2,56,,,,,,,,,,en,,,,,Crossref,,,,,,SB,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 8FJ5MMQX,conferencePaper,2005,"Giachetti, R.E.; Centeno, E.A.; Centeno, M.A.; Sundaram, R.",Assessing the Viability of an Open Access Policy in an Outpatient Clinic: A DiscreteEvent and Continuous Simulation Modeling Approach,"Proceedings of the Winter Simulation Conference, 2005.",978-0-7803-9519-0,,10.1109/WSC.2005.1574513,http://ieeexplore.ieee.org/document/1574513/,"This paper presents the preliminary results of an ongoing research project investigating the patient appointment scheduling for an outpatient clinic. The outpatient clinic was experiencing three problems of long patient throughput times, a large backlog of appointments, and a high no-show rate. We believe a new scheduling approach called open access could address all three problems. To analyze and make recommendations for improvement to patient cycle time we developed a discrete event simulation. To understand the factors leading to a high no-show rate we developed a systems dynamic simulation model. The study identified feasible strategies the clinic management could implement to greatly improve patient throughput time by 50%. Our preliminary results indicate that open access is a viable strategy for the clinic. Ongoing work is being conducted to refine the models and determine the best configuration of an open access scheduling policy for the outpatient clinic",2005,10/05/2019 10:18,14/04/2020 08:34,10/05/2019 10:18,2246-2255,,,,,,Assessing the Viability of an Open Access Policy in an Outpatient Clinic,,,,,IEEE,"Orlando, FL. USA",,,,,,Crossref,,,,,,SB,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Winter Simulation Conference, 2005.",,,,,,,,,,,,,,, VLA6MAJN,conferencePaper,2005,"Wijewickrama, A.; Takakuwa, S.",Simulation Analysis of Appointment Scheduling in an Outpatient Department of Internal Medicine,"Proceedings of the Winter Simulation Conference, 2005.",978-0-7803-9519-0,,10.1109/WSC.2005.1574515,http://ieeexplore.ieee.org/document/1574515/,"Long waiting times for treatment in the outpatient department of internal medicine, followed by short consultations has long been a complaint of patients. This issue is becoming increasingly important in Japan with the progressively aging society. In this context, a discrete event simulation model to examine various appointment schedules in a mixed-patient type environment in an outpatient department of a general hospital was developed. A special purpose data generator was designed to validate the model and to conduct experiments in bottleneck situations at consultation rooms in the existing system. Some efficient appointment schedules (ASs) were identified, which drastically reduced patient waiting time while keeping doctor idle time as low as possible without adding extra resources. The sensitivity of performance was examined under three realistic environmental factors: no show, variance of consultation time, and variation of walk-ins.",2005,10/05/2019 10:20,14/04/2020 08:34,10/05/2019 10:20,2264-2273,,,,,,,,,,,IEEE,"Orlando, FL. USA",,,,,,Crossref,,,,,,SB,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Winter Simulation Conference, 2005.",,,,,,,,,,,,,,, MF723V2X,journalArticle,2003,"Osidach, V.Z.; M.C. Fu.",Public health: computer simulation of a mobile examination center.,Proceedings of 2003 Winter Simulation Conference,,,10.1145/1030818.1031076,,,2003,10/05/2019 10:22,14/04/2020 08:34,,,,,,,,,,,,,,,,"Piscataway, New Jersey: Institute of Electrical and Electronics Engineers, Inc",,,,,,"ed. S.E. Chick, P.J. Sanchez, D.M. Ferrin, and D.J. Morrice, 1868-1875",,,,SB,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JTHZUKZ6,journalArticle,2003,"Blasak, R.E., D.W. Starks, W.S. Armel, and M.C. Hayduk","Healthcare process analysis: the use of simulation to evaluate hospital operations between the emer-gency department and a medical telemetry unit. In Proceedings of 2003 Winter Simulation Conference, ed. S.E. Chick, P.J. Sanchez, D.M. Ferrin, and D.J. Morrice, 1887-1893. Piscataway, New Jersey: Institute of Electrical and Electronics Engineers, Inc.",,,,DOI:10.1145/1030818.1031079,,"This paper presents a simulation model of the operations in the Emergency Department (ED) and Medical Telemetry (Med Tele) Units at Rush North Shore Medical Center. The model allows management to see the operations of both units as well as how the processes of each unit impact the other. Due to the large amount of variability that can take place within these units, Rush North Shore Medical Center along with Cap Gemini Ernst & Young sought the use of simulation to help evaluate their operations and provide insight into possible areas for improvement. Rockwell Automation created a model which depicts the current operations and evaluates possible alternatives to reduce the length of stay in the ED and improve operations. Using simulation, the hospital was able to select two to three key changes, rather than creating more stress with ten or more changes, to get the same result.",2003,10/05/2019 10:25,14/04/2020 08:34,,,,,,,,,,,,,,,,,,,,,,,,,,SB,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, DTLHD2FM,journalArticle,2005,"Ashton, R; Hague, L; Brandreth, M; Worthington, D; Cropper, S",A simulation-based study of a NHS Walk-in Centre,Journal of the Operational Research Society,,"0160-5682, 1476-9360",10.1057/palgrave.jors.2601883,https://www.tandfonline.com/doi/full/10.1057/palgrave.jors.2601883,"This paper describes a simulation-based project to help North Mersey Community National Health Service Trust to design and plan the operation of a NHS Walk-in Centre. The simulation model developed of this multi-service facility was used to facilitate managers and health professionals to recognize existing problems and potential future problems, and to investigate ideas for their ‘solution’. In the fast-moving NHS where initiatives to improve access, such as walk-in centres, are a recent development and where no two centres are the same, ideas for best practice borrowed from elsewhere can be quickly tested for suitability in the local situation.",2005-02,10/05/2019 10:26,14/04/2020 08:34,10/05/2019 10:26,153-161,,2,56,,,,,,,,,,en,,,,,Crossref,,,,,,SB,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 9NDJHE97,journalArticle,2006,"Kotiadis, K",Extracting a conceptual model for a complex integrated system in health care,"In Proceedings of the OR Society's Two-Day Workshop (SW06), 235-245",,,,,,2006,10/05/2019 10:27,14/04/2020 08:34,,,,,,,,,,,,,,,,,,,,,,,,,,******To read; SB,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ACZC6DIN,journalArticle,2007,"Matta, Marie E.; Patterson, Sarah Stock",Evaluating multiple performance measures across several dimensions at a multi-facility outpatient center,Health Care Management Science,,"1386-9620, 1572-9389",10.1007/s10729-007-9010-2,http://link.springer.com/10.1007/s10729-007-9010-2,"Over the past several decades healthcare delivery systems have received increased pressure to become more efficient from both a managerial and patient perspective. Many researchers have turned to simulation to analyze the complex systems that exist within hospitals, but surprisingly few have published guidelines on how to analyze models with multiple performance measures. Moreover, the published literature has failed to address ways of analyzing performance along more than one dimension, such as performance by day of the week, patient type, facility, time period, or some combination of these attributes. Despite this void in the literature, understanding performance along these dimensions is critical to understanding the root of operational problems in almost any daily clinic operation. This paper addresses the problem of multiple responses in simulation experiments of outpatient clinics by developing a stratification framework and an evaluation construct by which managers can compare several operationally different outpatient systems across multiple performance measure dimensions. This approach is applied to a discrete-event simulation model of a real-life, large-scale oncology center to evaluate its operational performance as improvement initiatives affecting scheduling practices, process flow, and resource levels are changed. Our results show a reduction in patient wait time and resource overtime across multiple patient classes, facilities, and days of the week. This research has already proven to be successful as certain recommendations have been implemented and have improved the system-wide performance at the oncology center.",18/05/2007,10/05/2019 10:28,14/04/2020 08:34,10/05/2019 10:28,173-194,,2,10,,,,,,,,,,en,,,,,Crossref,,,,,,******To read; SB,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, KWM5ZM7J,journalArticle,2003,"Honeycutt, Amanda A.; Boyle, James P.; Broglio, Kristine R.; Thompson, Theodore J.; Hoerger, Thomas J.; Geiss, Linda S.; Narayan, K. M. Venkat",A Dynamic Markov Model for Forecasting Diabetes Prevalence in the United States through 2050,Health Care Management Science,,1386-9620,,,"This study develops forecasts of the number of people with diagnosed diabetes and diagnosed diabetes prevalence in the United States through the year 2050. A Markov modeling framework is used to generate forecasts by age, race and ethnicity, and sex. The model forecasts the number of individuals in each of three states (diagnosed with diabetes, not diagnosed with diabetes, and death) in each year using inputs of estimated diagnosed diabetes prevalence and incidence; the relative risk of mortality from diabetes compared with no diabetes; and U.S. Census Bureau estimates of current population, live births, net migration, and the mortality rate of the general population. The projected number of people with diagnosed diabetes rises from 12.0 million in 2000 to 39.0 million in 2050, implying an increase in diagnosed diabetes prevalence from 4.4% in 2000 to 9.7% in 2050.",2003-08,10/05/2019 10:30,14/04/2020 08:34,,155-164,,3,6,,Health Care Manag Sci,,,,,,,,eng,,,,,PubMed,,PMID: 12943151,,,http://www.ncbi.nlm.nih.gov/pubmed/12943151,SB,Humans; United States; Markov Chains; Prevalence; Age Factors; Sex Factors; Ethnic Groups; Continental Population Groups; Diabetes Mellitus,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, VPP2KS5T,journalArticle,2013,"Mahamoud, Aziza; Roche, Brenda; Homer, Jack","Modelling the social determinants of health and simulating short-term and long-term intervention impacts for the city of Toronto, Canada",Social Science & Medicine,,2779536,10.1016/j.socscimed.2012.06.036,https://linkinghub.elsevier.com/retrieve/pii/S0277953612006880,"There is a substantial body of evidence highlighting the importance of the social determinants of health in shaping the health of urban populations in Canada. The low socio-economic status of marginalized, disadvantaged, and precarious populations in urban settings has been linked to adverse health outcomes including chronic and infectious disease, negative health behaviours, barriers to accessing health care services, and overall mortality. Given the dynamic complexities and inter-relationships surrounding the underlying drivers of population health outcomes and inequities, it is difficult to assess program and policy intervention tradeoffs, particularly when such interventions are studied with static models. To address this challenge, we have adopted a systems science approach and developed a simulation model for the City of Toronto, Canada, utilizing system dynamics modelling methodology. The model simulates changes in health, social determinants, and disparities from 2006 and projects forward to 2046 under different assumptions. Most of the variables in the model are stratified by ethnicity, immigration status, and gender, and capture the characteristics of adults aged 25-64. Intervention areas include health care access, behaviour, income, housing, and social cohesion. The model simulates alternative scenarios to help demonstrate the relative impact of different interventions on poor health outcomes such as chronic disease rates, disability rates, and mortality rate. It gives insight into how much, and how quickly, interventions can reduce mortality and morbidity. We believe this will serve as a useful learning tool to allow diverse stakeholders and policy makers to ask ""what if"" questions and map effective policy directions for complex population health problems, and will enable communities to think about their health futures.",2013-09,10/05/2019 12:51,14/04/2020 08:34,10/05/2019 12:51,247-255,,,93,,,,,,,,,,en,,,,,Crossref,,,,,,Review,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, YYSWURYS,journalArticle,2010,"Homer, Jack; Milstein, Bobby; Wile, Kristina; Trogdon, Justin; Huang, Philip; Labarthe, Darwin; Orenstein, Diane",Simulating and evaluating local interventions to improve cardiovascular health,Preventing Chronic Disease,,1545-1151,,,"Numerous local interventions for cardiovascular disease are available, but resources to deliver them are limited. Identifying the most effective interventions is challenging because cardiovascular risks develop through causal pathways and gradual accumulations that defy simple calculation. We created a simulation model for evaluating multiple approaches to preventing and managing cardiovascular risks. The model incorporates data from many sources to represent all US adults who have never had a cardiovascular event. It simulates trajectories for the leading direct and indirect risk factors from 1990 to 2040 and evaluates 19 interventions. The main outcomes are first-time cardiovascular events and consequent deaths, as well as total consequence costs, which combine medical expenditures and productivity costs associated with cardiovascular events and risk factors. We used sensitivity analyses to examine the significance of uncertain parameters. A base case scenario shows that population turnover and aging strongly influence the future trajectories of several risk factors. At least 15 of 19 interventions are potentially cost saving and could reduce deaths from first cardiovascular events by approximately 20% and total consequence costs by 26%. Some interventions act quickly to reduce deaths, while others more gradually reduce costs related to risk factors. Although the model is still evolving, the simulated experiments reported here can inform policy and spending decisions.",2010-01,10/05/2019 12:52,14/04/2020 08:34,,A18,,1,7,,Prev Chronic Dis,,,,,,,,eng,,,,,PubMed,,PMID: 20040233 PMCID: PMC2811513,,,http://www.ncbi.nlm.nih.gov/pubmed/20040233,Review,"Humans; United States; Health Care Costs; Community Health Services; Risk Factors; Cost of Illness; Time Factors; Costs and Cost Analysis; Models, Economic; Models, Biological; Cardiovascular Diseases",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, SRWXFDG5,document,2004,"Wolstenholme, Eric; Smith, Gill",Using system dynamics in modelling health and social care commissioning in the UK,,,,,,"Over the past two years OLM Consulting, initially in partnership with Cognitus, have used System Dynamics (SD) modelling in a wide range of health and social care settings to shed light on a number of difficult and complex issues and to influence and interpret health and social care policy in the UK. This work has been instrumental in causing health legislation to be modified in the Upper House of Parliament as well as helping local health communities implement sustainable performance improvement. This paper describes the work done in 2003 with two local health economies. It shows the commissioning models that resulted from applying a nationally-developed template in a local context, as well as some of the findings obtained from running those models. The emphasis has been on demonstrating strategies that achieve efficiency improvements for all agencies across whole patient pathways. By modelling whole pathways from primary care through acute care to post acute care, and focusing on admission prevention and delayed discharges, it has been possible to show that significant resources can be saved within agencies along the pathways, without influencing performance.",2004,10/05/2019 12:54,14/04/2020 08:34,,,,,,,,,,,,,"OLM Consulting, Cairns House, 10 Station Road, Teddington, Middlesex, TW11 9AA",,,OLM Consulting,,,,,,,,,,Review,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4XBUA4LG,journalArticle,2001,"Tengs, T. O.; Osgood, N. D.; Chen, L. L.",The cost-effectiveness of intensive national school-based anti-tobacco education: results from the tobacco policy model,Preventive Medicine,,0091-7435,10.1006/pmed.2001.0922,,"OBJECTIVES: School-based anti-tobacco education using the ""social influences"" model is known to reduce smoking among youth by 5-56%. Program effectiveness, however, dissipates in 1-4 years. Consequently, opinion leaders have questioned whether a more intensive national educational effort would be economically efficient. To address this question, we evaluated the cost-effectiveness of enhanced nationwide school-based anti-tobacco education relative to the status quo. METHODS: To estimate cost-effectiveness, we created the Tobacco Policy Model, a system dynamics computer simulation model. The model relies on secondary data and is designed to calculate the expected costs and public health gains of any tobacco policy or intervention over any time frame. RESULTS: Over 50 years, cost-effectiveness is estimated to lie between $4,900 and $340,000 per quality-adjusted life-year (QALY), depending on the degree and longevity of program effectiveness. Assuming a 30% effectiveness that dissipates in 4 years, cost-effectiveness is $20,000/QALY. Sensitivity analysis reveals that cost-effectiveness varies with cost, survival, and quality-of-life estimates but cost-effectiveness ratios generally remain favorable. CONCLUSIONS: Although not cost saving, a much more intensive school-based anti-tobacco educational effort would be an economically efficient investment for the nation.",2001-12,10/05/2019 12:58,14/04/2020 08:34,,558-570,,6,33,,Prev Med,The cost-effectiveness of intensive national school-based anti-tobacco education,,,,,,,eng,,,,,PubMed,,PMID: 11716651,,,http://www.ncbi.nlm.nih.gov/pubmed/11716651,Review,"Humans; United States; Cost-Benefit Analysis; Quality-Adjusted Life Years; Adult; Female; Male; Child; Adolescent; Models, Economic; Smoking Prevention; Health Education; Smoking; Demography",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JBGAENIW,journalArticle,2010,"Tobias, Martin I.; Cavana, Robert Y.; Bloomfield, Ashley",Application of a System Dynamics Model to Inform Investment in Smoking Cessation Services in New Zealand,American Journal of Public Health,,"0090-0036, 1541-0048",10.2105/AJPH.2009.171165,http://ajph.aphapublications.org/doi/10.2105/AJPH.2009.171165,"Objectives. We estimated the long-term effects of smoking cessation interventions to inform government decision-making regarding investment in tobacco control. Methods. We extracted data from the 2006 New Zealand Tobacco Use Survey and other sources and developed a system dynamics model with the iThink computer simulation package. The model derived estimates of population cessation rates from smoking behaviors and applied these over a 50-year period, from 2001 to 2051, under business-as-usual and enhanced cessation intervention scenarios. Results. The model predicted larger effects by 2051 with the enhanced cessation than with the business-as-usual scenario, including: an 11% greater decline in adult current smoking prevalence (9 versus 10 per 100 people), 16% greater decline in per capita tobacco consumption (370 versus 440 cigarette equivalents per year), and 11% greater reduction in tobacco-attributable mortality (3000 versus 3300 deaths per year). Conclusions. The model generated reliable estimates of the effects on health and on tobacco use of interventions designed to enhance smoking cessation. These results informed a decision announced in May 2007 to increase funding for smoking cessation by NZ $42 million over 4 years.",2010-07,10/05/2019 12:59,14/04/2020 08:34,10/05/2019 12:59,1274-1281,,7,100,,,,,,,,,,en,,,,,Crossref,,,,,,Review,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, JZIFQEZ3,conferencePaper,2008,"Medeiros, D. J.; Swenson, Eric; DeFlitch, Christopher",IMPROVING PATIENT FLOW IN A HOSPITAL EMERGENCY DEPARTMENT,Proceedings of the 2008 Winter Simulation Conference,978-1-4244-2708-6/08/$25.00 ©2008 IEEE,,https://www.informs-sim.org/wsc08papers/186.pdf,,"Hospital emergency departments in the US are facing increasing challenges due to growth in patient demand for their services, and inability to increase capacity to match demand. We report on a new approach to patient flow in emergency departments, and a simulation model of the approach. Initial results from the model show that the approach is feasible, and a pilot study demonstrates substantial improvements in patient care.",2008,24/02/2020 10:12,14/04/2020 08:34,,,,,,,,,,,,,IEEE,,,,,,,,,"S. J. Mason, R. R. Hill, L. Mönch, O. Rose, T. Jefferson, J. W. Fowler eds",,,,SB,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, N8E7EVVJ,document,2011,"McKelvie, Douglas; Wolstenholme, Eric; Arnold, Steve; Monk, David",Using System Dynamics to Plan Investment in Alcohol Services,,,,,,"The authors developed a Dynamic Whole System Model of Alcohol Harm Reduction for the England Department of Health, to support local commissioning of alcohol related services. The project used group model building, based on the best evidence available. It is intended to help local health commissioners reduce hospital admissions attributable to alcohol. The main “high impact” interventions incorporated are ‘brief advice’ in Primary Care, the employment of Alcohol Health Workers in hospital, and Specialised Treatment. The key output measures are hospital admissions and costs. The model uses four consumption groups (Abstainers; Lower Risk; Increasing Risk; Higher Risk) including ‘binge’ and ‘dependent’ drinkers in more than one state. Each state has a differing propensity for hospital admissions. The model provides a dynamic cost analysis; as interventions move people between states hence changing their risk of admission to hospital. The model contains a set of policies parameterised by the Department of Health, but also allows for local settings. The work relates to the search for consistent and cohesive policies by which central government can guide local actions. The approach of using dynamic models goes beyond action lists for guidance and allows localities to learn what will work for them. Key Words: alcohol consumption, system dynamics, health, modelling, UK",2011,24/02/2020 10:19,14/04/2020 08:34,,,,,,,,,,,,,The Symmetric Partnership,,,,,,,,,"The Grain Store, 127 Gloucester Road, Brighton, United Kingdom BN1 4AF",,,,X; GL,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,