# log2FoldChange: fold change of WT/Mutant in log2 by DESeq2 # n_isoforms: number of isoforms in the gene # gene_sig: if the gene is differentially expressed between WT and mutants # gene_exprs_perc: percentage of this isoform in total gene expression (isoform count/gene count) # is_major_isoform: if this isoform has more than 50% of the gene expression (gene_exprs_perc>0.5) transcript gene type log2FoldChange padj n_isoforms gene_sig long_total gene_count gene_exprs_perc is_major_isoform TUBB3-201 AC092143.1 REF 4.555086239 9.71E-04 1 TRUE 50 50 1 TRUE ACTA2-201 ACTA2 REF 1.469871381 1.64E-10 4 TRUE 24925 25260 0.986737926 TRUE ACTA2-204 ACTA2 REF 1.837832047 1.06E-05 4 TRUE 273 25260 0.010807601 FALSE ACTG2-201 ACTG2 REF 4.439154737 9.70E-06 2 TRUE 197 205 0.96097561 TRUE AGT-201 AGT REF 1.162941787 3.48E-05 1 TRUE 505 505 1 TRUE ALDH3A2-201 ALDH3A2 REF 1.26982945 9.71E-04 7 TRUE 473 581 0.814113597 TRUE ANKRD1-201 ANKRD1 REF 2.787362656 3.75E-05 1 TRUE 659 659 1 TRUE ANXA2-204 ANXA2 REF 0.945333526 3.60E-04 8 TRUE 1227 1391 0.882099209 TRUE AP002884.3-203 AP002884.3 REF 3.149452724 8.50E-05 2 TRUE 83 99 0.838383838 TRUE ARL4D-201 ARL4D REF 1.67854861 3.60E-04 1 TRUE 243 243 1 TRUE ASCL1-201 ASCL1 REF 2.288751519 4.71E-12 1 TRUE 421 421 1 TRUE ASPN-202 ASPN REF 2.945092597 3.62E-04 2 TRUE 83 85 0.976470588 TRUE BCL2A1-201 BCL2A1 REF 5.908406368 6.24E-05 1 TRUE 33 33 1 TRUE BNIP3-201 BNIP3 REF -1.190429038 3.00E-06 3 TRUE 2288 2327 0.983240223 TRUE C4orf46-201 C4orf46 REF 1.575966896 1.71E-05 2 TRUE 273 309 0.883495146 TRUE CALD1-202 CALD1 REF 6.065128861 7.36E-05 6 FALSE 35 123 0.284552846 FALSE CASQ2-201 CASQ2 REF 1.933793445 1.28E-10 1 TRUE 1103 1103 1 TRUE CAV3-201 CAV3 REF 4.161481965 4.04E-06 1 TRUE 82 82 1 TRUE CAVIN4-201 CAVIN4 REF 1.431940448 9.51E-04 1 TRUE 355 355 1 TRUE CCL2-201 CCL2 REF 5.735832837 6.03E-04 1 TRUE 27 27 1 TRUE CCND1-201 CCND1 REF 1.427754412 2.81E-04 4 TRUE 696 715 0.973426573 TRUE CD200-201 CD200 REF 2.163599296 8.60E-05 3 TRUE 129 150 0.86 TRUE CDC42EP3-201 CDC42EP3 REF 1.574450443 2.71E-11 3 TRUE 2845 2878 0.988533704 TRUE CHCHD3-203 CHCHD3 REF 4.632969669 9.57E-04 2 FALSE 53 1340 0.039552239 FALSE CNN1-201 CNN1 REF 4.238387147 1.50E-05 2 TRUE 340 358 0.94972067 TRUE CNN3-201 CNN3 REF 1.655505536 5.77E-10 3 TRUE 1141 1151 0.991311903 TRUE COL3A1-201 COL3A1 REF 5.956421998 1.42E-04 1 TRUE 32 32 1 TRUE COTL1-201 COTL1 REF 3.537248917 3.44E-06 2 TRUE 104 107 0.971962617 TRUE COX6A2-201 COX6A2 REF -1.653119601 4.47E-05 2 TRUE 319 334 0.95508982 TRUE CRABP2-203 CRABP2 REF 3.449443471 5.04E-04 1 TRUE 766 766 1 TRUE CRMP1-202 CRMP1 REF 2.213162535 6.03E-04 2 TRUE 94 101 0.930693069 TRUE CSRP2-201 CSRP2 REF 0.976894317 1.74E-05 4 TRUE 1291 1402 0.920827389 TRUE CXCL12-201 CXCL12 REF 2.091540697 7.05E-14 4 TRUE 1362 1383 0.984815618 TRUE DAAM1-207 DAAM1 REF 3.606529509 9.57E-04 12 FALSE 54 244 0.221311475 FALSE DECR1-201 DECR1 REF -0.917380859 8.09E-04 4 TRUE 1685 1799 0.936631462 TRUE FAM129A-201 FAM129A REF 3.175762679 3.60E-04 1 TRUE 66 66 1 TRUE FHL1-204 FHL1 REF 2.720779855 1.74E-05 14 TRUE 564 3104 0.181701031 FALSE FHL1-205 FHL1 REF 1.46733004 6.94E-10 14 TRUE 2177 3104 0.701353093 TRUE FILIP1L-203 FILIP1L REF 4.258981554 3.94E-07 1 TRUE 98 98 1 TRUE FLRT2-201 FLRT2 REF 1.115056027 4.13E-04 3 TRUE 666 707 0.942008487 TRUE GATB-204 GATB REF 1.872142014 5.44E-07 5 FALSE 392 847 0.462809917 FALSE GJA1-201 GJA1 REF 4.985884907 8.13E-08 1 TRUE 196 196 1 TRUE GJA5-203;GJA5-201 GJA5 REF 1.67698915 3.48E-08 2 TRUE 604 654 0.923547401 TRUE GLUL-202 GLUL REF -0.650354732 9.73E-04 5 TRUE 2370 2484 0.95410628 TRUE GNAI1-201 GNAI1 REF 1.530877625 3.70E-04 1 TRUE 251 251 1 TRUE GSN-SL1 GSN NC 1.16657042 6.88E-04 10 FALSE 520 1139 0.456540825 FALSE GYPC-201 GYPC REF 2.399465019 5.96E-07 2 TRUE 179 199 0.899497487 TRUE HIST1H4H-202;HIST1H4H-204 HIST1H4H REF 2.572730382 9.59E-04 1 TRUE 78 78 1 TRUE HLA-A-203 HLA-A REF 1.417588603 9.16E-04 3 FALSE 230 250 0.92 TRUE HNMT-202 HNMT REF 3.475405325 5.92E-07 4 TRUE 106 118 0.898305085 TRUE HSPB1-201 HSPB1 REF 0.818186962 3.43E-04 2 TRUE 19526 19668 0.99278015 TRUE HSPB8-201 HSPB8 REF 1.84408854 2.53E-13 3 TRUE 2089 2101 0.994288434 TRUE IFITM3-201 IFITM3 REF 0.998352989 1.22E-05 1 TRUE 3481 3481 1 TRUE IMMT-SL1 IMMT ASS -3.928985139 2.29E-04 7 FALSE 89 843 0.105575326 FALSE IMMT-SL2 IMMT ASS -3.721560514 9.71E-04 7 FALSE 75 843 0.088967972 FALSE KCNMB1-201 KCNMB1 REF 4.691128782 2.50E-04 2 TRUE 57 59 0.966101695 TRUE KRT18-201 KRT18 REF 1.077412525 1.05E-05 3 TRUE 3291 3360 0.979464286 TRUE LGALS1-201 LGALS1 REF 2.990622662 5.53E-07 1 TRUE 1302 1302 1 TRUE LGMN-201 LGMN REF 1.038298872 1.26E-04 8 TRUE 832 1191 0.698572628 TRUE MFAP2-202 MFAP2 REF 1.916528499 7.45E-04 2 TRUE 181 247 0.732793522 TRUE MFAP4-201 MFAP4 REF 2.707216088 1.60E-17 4 TRUE 1059 1364 0.776392962 TRUE MFAP4-202 MFAP4 REF 2.446834747 3.27E-06 4 TRUE 145 1364 0.106304985 FALSE MFAP4-203 MFAP4 REF 3.308242586 3.96E-09 4 TRUE 159 1364 0.116568915 FALSE MLLT11-201 MLLT11 REF 1.013593392 3.72E-06 1 TRUE 2575 2575 1 TRUE MMP11-201 MMP11 REF 2.21042697 1.49E-06 3 TRUE 237 246 0.963414634 TRUE MYC-207;MYC-202;MYC-206 MYC REF -1.224582499 8.32E-04 3 TRUE 605 614 0.98534202 TRUE MYL12A-201 MYL12A REF 0.912461187 2.68E-04 6 TRUE 2909 3587 0.810984109 TRUE MYL12A-209;MYL12A-202 MYL12A REF 3.710050812 2.65E-05 6 TRUE 606 3587 0.168943407 FALSE MYLK-206 MYLK REF 5.837664761 1.80E-11 4 TRUE 13262 14090 0.941234918 TRUE MYLK-219 MYLK REF 5.094509367 5.04E-04 4 TRUE 49 14090 0.003477644 FALSE MYLK-220 MYLK REF 6.977487647 2.17E-07 4 TRUE 67 14090 0.004755145 FALSE MYLK-221 MYLK REF 5.952608015 1.15E-07 4 TRUE 712 14090 0.050532292 FALSE NKX2-6-201 NKX2-6 REF -1.786688407 1.27E-04 1 TRUE 218 218 1 TRUE NPPA-202 NPPA REF 3.782220735 1.20E-07 2 TRUE 4558 4567 0.998029341 TRUE NPPB-201 NPPB REF 4.026485433 1.30E-07 1 TRUE 1255 1255 1 TRUE PDE1A-201 PDE1A REF -1.800875137 1.71E-04 3 TRUE 231 389 0.593830334 TRUE PDK1-201 PDK1 REF -1.302441501 3.23E-05 4 TRUE 562 739 0.760487145 TRUE PDLIM3-203 PDLIM3 REF 4.210284187 1.31E-10 5 TRUE 1576 1629 0.967464702 TRUE PIK3IP1-201 PIK3IP1 REF 3.154779188 3.28E-04 3 TRUE 68 99 0.686868687 TRUE PKM-202 PKM REF -1.074179717 3.60E-04 9 FALSE 1336 1920 0.695833333 TRUE PMP22-203 PMP22 REF -1.371582381 1.42E-04 6 FALSE 767 2499 0.306922769 FALSE PPP1R14A-201 PPP1R14A REF 5.68502964 7.50E-04 3 FALSE 26 75 0.346666667 FALSE PPP1R14A-203 PPP1R14A REF 5.048615153 7.50E-04 3 FALSE 47 75 0.626666667 TRUE PPP1R3A-201 PPP1R3A REF -2.100633957 2.23E-06 3 TRUE 251 295 0.850847458 TRUE PROCR-201 PROCR REF 3.166228129 5.04E-04 1 TRUE 58 58 1 TRUE PRSS23-201 PRSS23 REF 1.605686977 3.70E-09 3 TRUE 1171 1234 0.948946515 TRUE PTN-201 PTN REF 1.605325184 2.71E-11 2 TRUE 705 708 0.995762712 TRUE RCAN1-202 RCAN1 REF 2.779373597 9.07E-05 4 TRUE 553 600 0.921666667 TRUE RGS5-201 RGS5 REF 1.960923947 7.33E-04 5 TRUE 1471 1517 0.969676994 TRUE RPS27L-201 RPS27L REF 0.824768728 2.13E-05 7 TRUE 3133 3342 0.937462597 TRUE S100A10-202 S100A10 REF 2.716685683 3.98E-05 1 TRUE 408 408 1 TRUE S100A11-201 S100A11 REF 4.45702741 9.16E-04 1 TRUE 109 109 1 TRUE SAT1-204 SAT1 REF 1.566275304 2.05E-08 6 TRUE 508 688 0.738372093 TRUE SELENOM-201 SELENOM REF 2.837166134 1.50E-09 5 TRUE 214 225 0.951111111 TRUE SH3BGRL-201 SH3BGRL REF 0.899230242 3.34E-05 2 TRUE 1206 1214 0.993410214 TRUE SH3BGRL3-201 SH3BGRL3 REF 1.331446508 5.13E-04 2 TRUE 476 483 0.985507246 TRUE SHISA5-206 SHISA5 REF 3.616384767 4.81E-10 3 TRUE 149 187 0.796791444 TRUE SLC26A9-SL1 SLC26A9 ASS -2.317931359 9.23E-08 1 TRUE 302 302 1 TRUE SNAP25-202 SNAP25 REF 4.229485532 2.30E-05 3 TRUE 70 96 0.729166667 TRUE SNX22-201 SNX22 REF 2.750605629 3.29E-05 2 TRUE 95 97 0.979381443 TRUE SPARC-201 SPARC REF 3.111619242 1.38E-06 3 TRUE 1387 1427 0.971969166 TRUE SPINT2-201 SPINT2 REF 1.859607576 6.35E-07 4 TRUE 413 454 0.90969163 TRUE SPON1-201 SPON1 REF 2.811471372 8.46E-06 2 TRUE 120 129 0.930232558 TRUE SULT1E1-201 SULT1E1 REF 6.74554816 2.12E-04 2 TRUE 225 233 0.965665236 TRUE SYNPO-204 SYNPO REF 4.31166095 1.06E-12 1 TRUE 202 202 1 TRUE TAGLN-201 TAGLN REF 2.784300244 1.37E-04 5 TRUE 85 3454 0.024609149 FALSE TAGLN-202 TAGLN REF 3.220519364 8.87E-08 5 TRUE 3226 3454 0.933989577 TRUE TAGLN-207 TAGLN REF 2.992333283 4.78E-07 5 TRUE 132 3454 0.038216561 FALSE TGM2-201 TGM2 REF 1.270678053 5.29E-04 4 TRUE 544 591 0.920473773 TRUE TIMP1-201 TIMP1 REF 3.632598722 3.53E-11 3 TRUE 199 206 0.966019417 TRUE TMEM189-203 TMEM189 REF 2.954003125 4.33E-05 5 TRUE 78 222 0.351351351 FALSE TMSB4X-204 TMSB4X REF 2.695642619 1.02E-05 3 TRUE 6608 6712 0.984505364 TRUE TNFRSF12A-201 TNFRSF12A REF 1.695898169 2.14E-04 3 TRUE 315 328 0.960365854 TRUE TPM1-201 TPM1 REF 3.973463198 1.32E-08 18 FALSE 129 35810 0.003602346 FALSE TPM1-220 TPM1 REF 2.873788784 1.50E-05 18 FALSE 416 35810 0.011616867 FALSE TPM2-203 TPM2 REF 3.68833557 9.71E-04 6 TRUE 179 1392 0.128591954 FALSE TPM2-SL1 TPM2 NC 2.217569021 1.71E-05 6 TRUE 160 1392 0.114942529 FALSE TPM4-201 TPM4 REF 1.757011307 3.74E-05 5 TRUE 390 893 0.436730123 FALSE TUBA4A-201 TUBA4A REF 3.924432574 3.23E-05 3 TRUE 70 72 0.972222222 TRUE TUBB2A-201 TUBB2A REF 1.568322948 1.03E-05 2 TRUE 375 380 0.986842105 TRUE TUBB6-201 TUBB6 REF 0.888224417 1.22E-04 7 TRUE 1578 1854 0.851132686 TRUE