GeneID Length BM-C-Expression BM-S-Expression log2FoldChange(BM-S/BM-C) Padj Up/Down-Regulation Pvalue Cellular Component Molecular Function Biological Process Kegg Orthology Nr Description 14283 1705 31.47832885 5.768183482 -2.44816999 2.19E-07 Down 1.34E-09 GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0042734//presynaptic membrane;GO:0043005//neuron projection "GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding" "GO:0034097//response to cytokine;GO:0032570//response to progesterone;GO:0007296//vitellogenesis;GO:0009629//response to gravity;GO:0061614//pri-miRNA transcription from RNA polymerase II promoter;GO:0043065//positive regulation of apoptotic process;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0031668//cellular response to extracellular stimulus;GO:0008285//negative regulation of cell proliferation;GO:0060674//placenta blood vessel development;GO:0007565//female pregnancy;GO:0042493//response to drug;GO:0009612//response to mechanical stimulus;GO:0051591//response to cAMP;GO:0001701//in utero embryonic development;GO:0007612//learning;GO:2000144//positive regulation of DNA-templated transcription, initiation;GO:0042542//response to hydrogen peroxide;GO:0045787//positive regulation of cell cycle;GO:0051412//response to corticosterone" K04502//fos-like antigen 1 NP_034365.1//fos-related antigen 1 [Mus musculus] 193740 2798 68.23117131 16.73829266 -2.027278606 8.71E-08 Down 5.02E-10 GO:0031982//vesicle;GO:0016234//inclusion body;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0016235//aggresome;GO:0005813//centrosome;GO:0016607//nuclear speck;GO:0048471//perinuclear region of cytoplasm;GO:0005814//centriole;GO:0030529//intracellular ribonucleoprotein complex;GO:0043234//protein complex "GO:0003723//RNA binding;GO:0055131//C3HC4-type RING finger domain binding;GO:0005524//ATP binding;GO:0047485//protein N-terminus binding;GO:0042826//histone deacetylase binding;GO:0031072//heat shock protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0005102//receptor binding;GO:0045296//cadherin binding;GO:0042623//ATPase activity, coupled;GO:0001106//RNA polymerase II transcription corepressor activity;GO:0001664//G-protein coupled receptor binding;GO:0051082//unfolded protein binding;GO:0097718//disordered domain specific binding;GO:0044183//protein binding involved in protein folding;GO:0031249//denatured protein binding;GO:0019899//enzyme binding;GO:0016887//ATPase activity" GO:0030308//negative regulation of cell growth;GO:0006986//response to unfolded protein;GO:0006281//DNA repair;GO:1901673//regulation of mitotic spindle assembly;GO:0009408//response to heat;GO:0006402//mRNA catabolic process;GO:0097201//negative regulation of transcription from RNA polymerase II promoter in response to stress;GO:0090063//positive regulation of microtubule nucleation;GO:0042026//protein refolding;GO:0000723//telomere maintenance;GO:0008285//negative regulation of cell proliferation K03283//heat shock 70kDa protein 1/2/6/8 NP_034609.2//heat shock 70 kDa protein 1A [Mus musculus] 15511 2810 137.909389 40.94841895 -1.751841026 1.68E-10 Down 6.31E-13 GO:0031982//vesicle;GO:0016234//inclusion body;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0016235//aggresome;GO:0005813//centrosome;GO:0016607//nuclear speck;GO:0048471//perinuclear region of cytoplasm;GO:0005814//centriole;GO:0030529//intracellular ribonucleoprotein complex;GO:0043234//protein complex "GO:0003723//RNA binding;GO:0055131//C3HC4-type RING finger domain binding;GO:0005524//ATP binding;GO:0047485//protein N-terminus binding;GO:0042826//histone deacetylase binding;GO:0031072//heat shock protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0005102//receptor binding;GO:0045296//cadherin binding;GO:0042623//ATPase activity, coupled;GO:0001106//RNA polymerase II transcription corepressor activity;GO:0001664//G-protein coupled receptor binding;GO:0051082//unfolded protein binding;GO:0097718//disordered domain specific binding;GO:0044183//protein binding involved in protein folding;GO:0031249//denatured protein binding;GO:0019899//enzyme binding;GO:0016887//ATPase activity" GO:0030308//negative regulation of cell growth;GO:0006986//response to unfolded protein;GO:0006281//DNA repair;GO:1901673//regulation of mitotic spindle assembly;GO:0009408//response to heat;GO:0006402//mRNA catabolic process;GO:0097201//negative regulation of transcription from RNA polymerase II promoter in response to stress;GO:0090063//positive regulation of microtubule nucleation;GO:0042026//protein refolding;GO:0000723//telomere maintenance;GO:0008285//negative regulation of cell proliferation K03283//heat shock 70kDa protein 1/2/6/8 NP_034609.2//heat shock 70 kDa protein 1A [Mus musculus] 14204 2059 8.497508325 2.687693206 -1.660671403 0.004488077 Down 9.23E-05 GO:0005764//lysosome GO:0001716//L-amino-acid oxidase activity;GO:0016491//oxidoreductase activity GO:0009072//aromatic amino acid family metabolic process K03334//L-amino-acid oxidase [EC:1.4.3.2] "EDL22757.1//interleukin 4 induced 1, partial [Mus musculus]" 319187 431 6.382947326 2.262754857 -1.496142448 0.014470701 Down 0.000368692 GO:0005634//nucleus;GO:0000786//nucleosome GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity NA K11252//histone H2B XP_003502246.1//PREDICTED: histone H2B type 1 isoform X1 [Cricetulus griseus] 13137 1029 19.32648842 7.109938834 -1.442670473 0.015582551 Down 0.000406089 GO:0070062//extracellular exosome;GO:0009986//cell surface;GO:0045121//membrane raft;GO:0016021//integral component of membrane;GO:0005886//plasma membrane GO:0008289//lipid binding;GO:0001618//virus receptor activity "GO:0006958//complement activation, classical pathway;GO:0045087//innate immune response" K04006//decay accelerating factor "EDL39744.1//mCG128397, partial [Mus musculus];NP_001304290.1//complement decay-accelerating factor transmembrane isoform isoform 2 precursor [Mus musculus]" 241075 8562 657.2378469 266.7452972 -1.300952724 1.01E-17 Down 1.31E-20 NA GO:0046872//metal ion binding NA K19330//run domain Beclin-1 interacting and cysteine-rich containing protein "EDL00211.1//mCG123132, isoform CRA_b, partial [Mus musculus]" 211401 4969 220.169632 90.57884217 -1.281369489 8.50E-10 Down 3.58E-12 GO:0015629//actin cytoskeleton;GO:0005737//cytoplasm;GO:0005912//adherens junction GO:0051015//actin filament binding;GO:0003779//actin binding;GO:0042802//identical protein binding;GO:0005102//receptor binding;GO:0003785//actin monomer binding GO:0007399//nervous system development;GO:0061333//renal tubule morphogenesis;GO:0072160//nephron tubule epithelial cell differentiation;GO:0071498//cellular response to fluid shear stress;GO:0010960//magnesium ion homeostasis;GO:0007015//actin filament organization;GO:0072102//glomerulus morphogenesis;GO:0072001//renal system development;GO:0007009//plasma membrane organization;GO:0030041//actin filament polymerization;GO:2001013//epithelial cell proliferation involved in renal tubule morphogenesis;GO:0030282//bone mineralization;GO:0030036//actin cytoskeleton organization;GO:0001701//in utero embryonic development;GO:0007517//muscle organ development;GO:0034334//adherens junction maintenance;GO:0032233//positive regulation of actin filament bundle assembly;GO:0050680//negative regulation of epithelial cell proliferation K20128//metastasis suppressor protein 1 "NP_001124035.1//metastasis suppressor protein 1 [Rattus norvegicus];BAC97949.1//mKIAA0429 protein, partial [Mus musculus]" 67876 1729 853.6902741 353.1467587 -1.273444888 8.44E-05 Down 9.44E-07 GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion GO:0048039//ubiquinone binding GO:0006744//ubiquinone biosynthetic process;GO:0045333//cellular respiration K18588//coenzyme Q-binding protein COQ10 "NP_080700.3//coenzyme Q-binding protein COQ10 homolog B, mitochondrial isoform 2 [Mus musculus];NP_001034799.1//coenzyme Q-binding protein COQ10 homolog B, mitochondrial isoform 1 [Mus musculus]" 22095 3562 107.9616713 49.4742628 -1.125769101 0.000257399 Down 3.36E-06 GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0043235//receptor complex GO:0004996//thyroid-stimulating hormone receptor activity;GO:0008528//G-protein coupled peptide receptor activity;GO:0004872//receptor activity;GO:0032403//protein complex binding GO:1904588//cellular response to glycoprotein;GO:0008344//adult locomotory behavior;GO:0007166//cell surface receptor signaling pathway;GO:0090103//cochlea morphogenesis;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:1905229//cellular response to thyrotropin-releasing hormone;GO:0030183//B cell differentiation;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0009755//hormone-mediated signaling pathway;GO:0071542//dopaminergic neuron differentiation;GO:0045762//positive regulation of adenylate cyclase activity;GO:0060122//inner ear receptor cell stereocilium organization;GO:0007190//activation of adenylate cyclase activity;GO:0060119//inner ear receptor cell development;GO:0040018//positive regulation of multicellular organism growth;GO:0040012//regulation of locomotion;GO:0038194//thyroid-stimulating hormone signaling pathway K04249//thyroid stimulating hormone receptor "EDL18952.1//thyroid stimulating hormone receptor, isoform CRA_a, partial [Mus musculus];NP_035778.3//thyrotropin receptor isoform 1 precursor [Mus musculus]" 17079 2326 158.7136333 73.00177897 -1.120422533 1.56E-05 Down 1.35E-07 GO:0005887//integral component of plasma membrane GO:0004872//receptor activity GO:0071222//cellular response to lipopolysaccharide;GO:0002322//B cell proliferation involved in immune response;GO:0002224//toll-like receptor signaling pathway;GO:0031666//positive regulation of lipopolysaccharide-mediated signaling pathway;GO:0006954//inflammatory response K06555//CD180 antigen BAA07043.1//RP105 [Mus musculus domesticus] 23872 3560 4027.331496 1904.905067 -1.080105126 0.002602721 Down 4.76E-05 GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane "GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0019904//protein domain specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0035259//glucocorticoid receptor binding;GO:0003700//DNA binding transcription factor activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding" "GO:0090009//primitive streak formation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007498//mesoderm development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001712//ectodermal cell fate commitment;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated" K21932//C-ets-2 NP_035939.3//protein C-ets-2 [Mus musculus] 20533 4584 87.89055788 41.72183443 -1.074905592 0.000850417 Down 1.34E-05 GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0016323//basolateral plasma membrane;GO:0072562//blood microparticle;GO:0030018//Z disc;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0030863//cortical cytoskeleton GO:0015108//chloride transmembrane transporter activity;GO:0015301//anion:anion antiporter activity;GO:0008510//sodium:bicarbonate symporter activity;GO:0005452//inorganic anion exchanger activity;GO:0030506//ankyrin binding;GO:0042803//protein homodimerization activity;GO:0015106//bicarbonate transmembrane transporter activity GO:0015701//bicarbonate transport;GO:0006820//anion transport;GO:0006821//chloride transport;GO:0051453//regulation of intracellular pH "K06573//solute carrier family 4 (anion exchanger), member 1" NP_035533.1//band 3 anion transport protein [Mus musculus] 55984 3466 138.0907918 66.41096124 -1.056123835 0.000253878 Down 3.30E-06 GO:0005634//nucleus;GO:0005737//cytoplasm GO:0005524//ATP binding;GO:0004683//calmodulin-dependent protein kinase activity;GO:0005516//calmodulin binding GO:0018107//peptidyl-threonine phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0045860//positive regulation of protein kinase activity;GO:0035556//intracellular signal transduction K00908//calcium/calmodulin-dependent protein kinase kinase 1 [EC:2.7.11.17] NP_061371.2//calcium/calmodulin-dependent protein kinase kinase 1 [Mus musculus] 108723 4112 66.75857564 32.28924394 -1.047899513 0.010002721 Down 0.000241271 GO:0042101//T cell receptor complex;GO:0070062//extracellular exosome;GO:0045121//membrane raft;GO:0005886//plasma membrane;GO:0001772//immunological synapse;GO:0005737//cytoplasm GO:0050700//CARD domain binding GO:0042102//positive regulation of T cell proliferation;GO:0045580//regulation of T cell differentiation;GO:0031295//T cell costimulation;GO:0001819//positive regulation of cytokine production;GO:0030890//positive regulation of B cell proliferation;GO:0046649//lymphocyte activation;GO:0030183//B cell differentiation;GO:0050776//regulation of immune response;GO:0042110//T cell activation;GO:0048872//homeostasis of number of cells;GO:0045061//thymic T cell selection;GO:0045577//regulation of B cell differentiation;GO:0007165//signal transduction;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0002377//immunoglobulin production;GO:0070970//interleukin-2 secretion;GO:0050870//positive regulation of T cell activation;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045086//positive regulation of interleukin-2 biosynthetic process;GO:0042100//B cell proliferation;GO:0042981//regulation of apoptotic process K07367//caspase recruitment domain-containing protein 11 "BAD21384.1//mFLJ00120 protein, partial [Mus musculus]" 241576 3907 191.1939286 93.81124544 -1.027203933 1.38E-05 Down 1.19E-07 GO:0016021//integral component of membrane;GO:0005886//plasma membrane GO:0001540//amyloid-beta binding GO:0070613//regulation of protein processing;GO:0006898//receptor-mediated endocytosis K06233//low density lipoprotein-related protein 2 XP_007521888.1//PREDICTED: low-density lipoprotein receptor class A domain-containing protein 3 isoform X1 [Erinaceus europaeus] 11855 5197 67.7381793 33.37983094 -1.020992562 0.015998893 Down 0.000420043 GO:0005783//endoplasmic reticulum;GO:0005829//cytosol GO:0005525//GTP binding;GO:0042169//SH2 domain binding;GO:0003924//GTPase activity GO:0007165//signal transduction;GO:0030879//mammary gland development K13709//Rho GTPase-activating protein 5 NP_033836.2//rho GTPase-activating protein 5 [Mus musculus] 380840 1515 38.67632961 78.46213448 1.020545694 0.003050448 Up 5.78E-05 GO:0016604//nuclear body;GO:0005739//mitochondrion NA NA K22069//LYR motif-containing protein 4 "EDL40910.1//cDNA sequence BC034664, partial [Mus musculus]" 21817 3549 1275.781044 2670.000559 1.065459296 7.14E-22 Up 4.62E-25 GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0031226//intrinsic component of plasma membrane;GO:0005783//endoplasmic reticulum;GO:0005925//focal adhesion;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix;GO:0005829//cytosol;GO:0005739//mitochondrion GO:0019904//protein domain specific binding;GO:0005509//calcium ion binding;GO:0008483//transaminase activity;GO:0005525//GTP binding;GO:0003810//protein-glutamine gamma-glutamyltransferase activity GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0060445//branching involved in salivary gland morphogenesis;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0045785//positive regulation of cell adhesion;GO:0051260//protein homooligomerization;GO:0050729//positive regulation of inflammatory response;GO:0051561//positive regulation of mitochondrial calcium ion concentration;GO:0018149//peptide cross-linking;GO:0043065//positive regulation of apoptotic process;GO:0060662//salivary gland cavitation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0043277//apoptotic cell clearance;GO:0032471//negative regulation of endoplasmic reticulum calcium ion concentration;GO:0001974//blood vessel remodeling;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0018153//isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine;GO:0048661//positive regulation of smooth muscle cell proliferation K05625//transglutaminase 2 [EC:2.3.2.13] "EDL06255.1//transglutaminase 2, C polypeptide, isoform CRA_a, partial [Mus musculus]" 57905 1620 328.0142143 695.2946116 1.083866074 4.20E-14 Up 1.01E-16 GO:0071020//post-spliceosomal complex;GO:0071012//catalytic step 1 spliceosome;GO:0000974//Prp19 complex;GO:0071014//post-mRNA release spliceosomal complex;GO:0071013//catalytic step 2 spliceosome NA GO:0000350//generation of catalytic spliceosome for second transesterification step;GO:0000389//mRNA 3'-splice site recognition K12870//pre-mRNA-splicing factor ISY1 XP_005071187.2//pre-mRNA-splicing factor ISY1 homolog [Mesocricetus auratus] 14726 1839 32.70639566 70.81936722 1.114571174 0.001102429 Up 1.80E-05 GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0042995//cell projection;GO:0009897//external side of plasma membrane;GO:0016324//apical plasma membrane;GO:0097197//tetraspanin-enriched microdomain;GO:0071437//invadopodium;GO:0031410//cytoplasmic vesicle;GO:0030054//cell junction;GO:0032587//ruffle membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0031527//filopodium membrane;GO:0030027//lamellipodium;GO:0030175//filopodium;GO:0001726//ruffle;GO:0031258//lamellipodium membrane;GO:0061851//leading edge of lamellipodium;GO:0045121//membrane raft;GO:0031528//microvillus membrane GO:0019956//chemokine binding;GO:0005102//receptor binding;GO:0051087//chaperone binding "GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:0030324//lung development;GO:1904328//regulation of myofibroblast contraction;GO:0030335//positive regulation of cell migration;GO:0070252//actin-mediated cell contraction;GO:0035239//tube morphogenesis;GO:0098609//cell-cell adhesion;GO:0060838//lymphatic endothelial cell fate commitment;GO:0008283//cell proliferation;GO:0051272//positive regulation of cellular component movement;GO:1905863//invadopodium organization;GO:1901731//positive regulation of platelet aggregation;GO:0044319//wound healing, spreading of cells;GO:0030155//regulation of cell adhesion;GO:0008285//negative regulation of cell proliferation;GO:0000902//cell morphogenesis;GO:0007165//signal transduction;GO:0048535//lymph node development;GO:0043066//negative regulation of apoptotic process;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0008360//regulation of cell shape;GO:0090091//positive regulation of extracellular matrix disassembly;GO:1900024//regulation of substrate adhesion-dependent cell spreading;GO:0061032//visceral serous pericardium development;GO:0007266//Rho protein signal transduction;GO:0007155//cell adhesion;GO:0006693//prostaglandin metabolic process;GO:2000392//regulation of lamellipodium morphogenesis;GO:0048286//lung alveolus development;GO:0001946//lymphangiogenesis" K16778//podoplanin NP_001277751.1//podoplanin isoform 2 precursor [Mus musculus];NP_034459.2//podoplanin isoform 1 precursor [Mus musculus] 100126226 1775 437.4151415 959.7645967 1.133677435 1.40E-20 Up 1.09E-23 GO:0005615//extracellular space;GO:0045095//keratin filament GO:0005198//structural molecule activity GO:0042633//hair cycle;GO:0007568//aging "K07605//type II keratin, basic" NP_001188252.1//type II hair keratin [Mus musculus] 102442 8655 2127.374857 4692.892937 1.14140328 3.21E-27 Up 1.45E-30 NA GO:0017112//Rab guanyl-nucleotide exchange factor activity NA K20163//DENN domain-containing protein 4 NP_001156389.1//C-myc promoter-binding protein [Mus musculus] 666938 7935 62.52308971 138.6573132 1.149062731 5.41E-05 Up 5.70E-07 NA NA NA K03129//transcription initiation factor TFIID subunit 4 NP_001158278.1//BEN domain-containing protein 4 [Mus musculus] 26556 4236 94.44049675 210.5571997 1.156734672 2.66E-08 Up 1.43E-10 GO:0016020//membrane;GO:0030424//axon;GO:0098794//postsynapse;GO:0043034//costamere;GO:0030054//cell junction;GO:0014069//postsynaptic density;GO:0005737//cytoplasm;GO:0043005//neuron projection;GO:0030018//Z disc;GO:0045177//apical part of cell;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane GO:0044325//ion channel binding;GO:0035256//G-protein coupled glutamate receptor binding GO:0048148//behavioral response to cocaine;GO:0007216//G-protein coupled glutamate receptor signaling pathway;GO:0048875//chemical homeostasis within a tissue;GO:0048741//skeletal muscle fiber development;GO:0090279//regulation of calcium ion import;GO:2001257//regulation of cation channel activity;GO:0051592//response to calcium ion;GO:2001256//regulation of store-operated calcium entry;GO:0003009//skeletal muscle contraction;GO:0051928//positive regulation of calcium ion transport K15010//homer "NP_671705.2//homer protein homolog 1 isoform L [Mus musculus];EDL00939.1//homer homolog 1 (Drosophila), isoform CRA_c, partial [Mus musculus];NP_001334527.1//homer protein homolog 1 isoform M [Mus musculus];NP_687036.1//homer protein homolog 1 isoform d [Mus musculus]" 30953 1535 14.53755811 32.83070905 1.17526095 0.043974776 Up 0.001509998 GO:0043194//axon initial segment;GO:0033268//node of Ranvier GO:0044325//ion channel binding;GO:0005516//calmodulin binding;GO:0030506//ankyrin binding GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0001822//kidney development;GO:0048745//smooth muscle tissue development;GO:0010761//fibroblast migration;GO:0008366//axon ensheathment;GO:0006807//nitrogen compound metabolic process;GO:0009791//post-embryonic development;GO:0001553//luteinization;GO:0008210//estrogen metabolic process;GO:0060325//face morphogenesis;GO:0060021//palate development;GO:0048705//skeletal system morphogenesis NA "NP_001106891.1//schwannomin-interacting protein 1 isoform b [Mus musculus];NP_001106892.1//schwannomin-interacting protein 1 isoform c [Mus musculus];EDL15509.1//schwannomin interacting protein 1, partial [Mus musculus]" 16180 4456 718.4757255 1628.638924 1.180655469 1.73E-38 Up 4.46E-42 GO:0016020//membrane;GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0005886//plasma membrane GO:1990782//protein tyrosine kinase binding;GO:0004871//signal transducer activity;GO:0002114//interleukin-33 receptor activity;GO:0004908//interleukin-1 receptor activity GO:1900006//positive regulation of dendrite development;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051965//positive regulation of synapse assembly;GO:0006954//inflammatory response;GO:0042094//interleukin-2 biosynthetic process;GO:0072602//interleukin-4 secretion;GO:0032754//positive regulation of interleukin-5 production;GO:0032736//positive regulation of interleukin-13 production;GO:0019221//cytokine-mediated signaling pathway;GO:0045087//innate immune response;GO:0038172//interleukin-33-mediated signaling pathway;GO:2000778//positive regulation of interleukin-6 secretion K04723//interleukin 1 receptor accessory protein "EDK97691.1//interleukin 1 receptor accessory protein, isoform CRA_b, partial [Mus musculus];NP_001152790.1//interleukin-1 receptor accessory protein isoform d precursor [Mus musculus];BAE43382.1//unnamed protein product [Mus musculus];EDK97692.1//interleukin 1 receptor accessory protein, isoform CRA_c, partial [Mus musculus]" 68603 1203 230.9643602 534.0711505 1.209361706 6.92E-11 Up 2.42E-13 GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005777//peroxisome GO:0005524//ATP binding;GO:0004631//phosphomevalonate kinase activity "GO:0070723//response to cholesterol;GO:0016126//sterol biosynthetic process;GO:0019287//isopentenyl diphosphate biosynthetic process, mevalonate pathway;GO:0006695//cholesterol biosynthetic process" K13273//phosphomevalonate kinase [EC:2.7.4.2] NP_081624.1//phosphomevalonate kinase isoform 2 [Mus musculus];NP_081060.2//phosphomevalonate kinase isoform 1 [Mus musculus] 26897 1559 400.3038934 926.6179672 1.210879009 1.53E-18 Up 1.89E-21 GO:0005739//mitochondrion;GO:0005737//cytoplasm GO:0047617//acyl-CoA hydrolase activity;GO:0102991//myristoyl-CoA hydrolase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0016290//palmitoyl-CoA hydrolase activity GO:0001676//long-chain fatty acid metabolic process;GO:0006637//acyl-CoA metabolic process K01068//acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2] NP_036136.1//acyl-coenzyme A thioesterase 1 [Mus musculus] 12350 1537 15.80943282 36.84892312 1.220836847 0.023109887 Up 0.000672494 GO:0005829//cytosol;GO:0005737//cytoplasm GO:0008270//zinc ion binding;GO:0004089//carbonate dehydratase activity;GO:0016791//phosphatase activity;GO:0016151//nickel cation binding GO:0006979//response to oxidative stress;GO:0006730//one-carbon metabolic process;GO:0045471//response to ethanol K01672//carbonic anhydrase [EC:4.2.1.1] NP_031632.2//carbonic anhydrase 3 [Mus musculus] 16833 1310 129.4033236 307.8630444 1.250414026 5.59E-10 Up 2.31E-12 GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0031514//motile cilium;GO:0005737//cytoplasm GO:0004459//L-lactate dehydrogenase activity GO:0006754//ATP biosynthetic process;GO:0030317//flagellated sperm motility;GO:0019516//lactate oxidation;GO:0005975//carbohydrate metabolic process;GO:0019244//lactate biosynthetic process from pyruvate K00016//L-lactate dehydrogenase [EC:1.1.1.27] XP_008757566.1//PREDICTED: L-lactate dehydrogenase C chain isoform X1 [Rattus norvegicus] 434197 2831 272.0673011 656.4588362 1.270740974 8.15E-16 Up 1.53E-18 NA NA NA K12869//crooked neck NP_001013833.1//protein FAM169B [Mus musculus] 216505 2267 68.02933848 167.4714584 1.299686278 4.02E-09 Up 1.90E-11 NA NA NA K01343//tissue plasminogen activator [EC:3.4.21.68] "EDL40410.1//RIKEN cDNA 1500004A08, isoform CRA_c, partial [Mus musculus]" 20720 2071 133.4963665 332.7717575 1.317732522 1.52E-14 Up 3.54E-17 GO:0031012//extracellular matrix;GO:0005615//extracellular space;GO:0031091//platelet alpha granule;GO:0005829//cytosol;GO:0031594//neuromuscular junction;GO:0031232//extrinsic component of external side of plasma membrane;GO:0005576//extracellular region;GO:1903561//extracellular vesicle GO:0004867//serine-type endopeptidase inhibitor activity;GO:0008201//heparin binding;GO:0005539//glycosaminoglycan binding;GO:0005102//receptor binding "GO:0045861//negative regulation of proteolysis;GO:0007596//blood coagulation;GO:0021683//cerebellar granular layer morphogenesis;GO:0042177//negative regulation of protein catabolic process;GO:0045879//negative regulation of smoothened signaling pathway;GO:0010955//negative regulation of protein processing;GO:0010544//negative regulation of platelet activation;GO:0010766//negative regulation of sodium ion transport;GO:0060291//long-term synaptic potentiation;GO:0090331//negative regulation of platelet aggregation;GO:0042628//mating plug formation;GO:0008285//negative regulation of cell proliferation;GO:0009611//response to wounding;GO:0030308//negative regulation of cell growth;GO:0060384//innervation;GO:0030195//negative regulation of blood coagulation;GO:0010466//negative regulation of peptidase activity;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0010757//negative regulation of plasminogen activation;GO:0033363//secretory granule organization;GO:0032940//secretion by cell;GO:0048505//regulation of timing of cell differentiation;GO:0061108//seminal vesicle epithelium development;GO:0048711//positive regulation of astrocyte differentiation;GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0050974//detection of mechanical stimulus involved in sensory perception" K16643//glia-derived nexin NP_033281.1//glia-derived nexin precursor [Mus musculus] 20750 1431 136.1687949 340.0237249 1.320239286 7.09E-12 Up 2.11E-14 GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005794//Golgi apparatus GO:0050840//extracellular matrix binding "GO:0001649//osteoblast differentiation;GO:0007155//cell adhesion;GO:0071394//cellular response to testosterone stimulus;GO:0006710//androgen catabolic process;GO:2000866//positive regulation of estradiol secretion;GO:0033280//response to vitamin D;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045780//positive regulation of bone resorption" K06250//secreted phosphoprotein 1 BAE38751.1//unnamed protein product [Mus musculus] 58205 3415 14.02499163 35.11855171 1.324233439 0.008816433 Up 0.000208666 GO:0070062//extracellular exosome;GO:0016021//integral component of membrane NA GO:0042130//negative regulation of T cell proliferation;GO:0046007//negative regulation of activated T cell proliferation;GO:0032693//negative regulation of interleukin-10 production;GO:0042102//positive regulation of T cell proliferation;GO:0032689//negative regulation of interferon-gamma production K06708//programmed cell death 1 ligand 2 "EDL41682.1//programmed cell death 1 ligand 2, isoform CRA_a, partial [Mus musculus]" 12406 2229 5.308496374 13.40994433 1.336928065 0.047968872 Up 0.001706084 GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005783//endoplasmic reticulum;GO:0045121//membrane raft;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005737//cytoplasm GO:0003723//RNA binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005518//collagen binding;GO:0051082//unfolded protein binding GO:0003433//chondrocyte development involved in endochondral bone morphogenesis;GO:0051604//protein maturation;GO:0030199//collagen fibril organization;GO:0032964//collagen biosynthetic process "K09501//serpin peptidase inhibitor, clade H, member 1" XP_008018373.1//PREDICTED: serpin H1 isoform X1 [Chlorocebus sabaeus];NP_033955.2//serpin H1 precursor [Mus musculus] 13179 1881 7.126982625 18.27820741 1.358761276 0.032466439 Up 0.001018151 GO:0031012//extracellular matrix;GO:0005589//collagen type VI trimer;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix GO:0003723//RNA binding;GO:0004860//protein kinase inhibitor activity;GO:0005518//collagen binding;GO:0047485//protein N-terminus binding;GO:0005539//glycosaminoglycan binding;GO:0050840//extracellular matrix binding GO:0001822//kidney development;GO:0032496//response to lipopolysaccharide;GO:0001890//placenta development;GO:0051901//positive regulation of mitochondrial depolarization;GO:0009612//response to mechanical stimulus;GO:0019800//peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan;GO:0090141//positive regulation of mitochondrial fission;GO:1900747//negative regulation of vascular endothelial growth factor signaling pathway;GO:0016525//negative regulation of angiogenesis;GO:0010596//negative regulation of endothelial cell migration;GO:0042060//wound healing;GO:0046426//negative regulation of JAK-STAT cascade;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0010508//positive regulation of autophagy;GO:0007568//aging;GO:0006469//negative regulation of protein kinase activity;GO:0016239//positive regulation of macroautophagy;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007519//skeletal muscle tissue development;GO:0019221//cytokine-mediated signaling pathway K04660//decorin NP_031859.1//decorin preproprotein [Mus musculus] 85031 1994 7.083831246 18.88405896 1.414567144 0.020009971 Up 0.000561584 NA NA NA K13618//phospholipase A1 member A [EC:3.1.1.-] XP_021040406.1//phospholipase A1 member A isoform X1 [Mus caroli] 68519 3806 20.66914221 55.79268323 1.43259742 0.000796958 Up 1.21E-05 NA NA NA K18595//echinoderm microtubule-associated protein-like 1/2 XP_017383632.1//PREDICTED: echinoderm microtubule-associated protein-like 1 isoform X8 [Cebus capucinus imitator];XP_017383629.1//PREDICTED: echinoderm microtubule-associated protein-like 1 isoform X5 [Cebus capucinus imitator];XP_017383631.1//PREDICTED: echinoderm microtubule-associated protein-like 1 isoform X7 [Cebus capucinus imitator] 17381 3607 7.332285906 20.45062305 1.47980985 0.017881041 Up 0.000483334 GO:0031012//extracellular matrix;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix GO:0004252//serine-type endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005518//collagen binding;GO:0005509//calcium ion binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0001047//core promoter binding "GO:0014070//response to organic cyclic compound;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:1901163//regulation of trophoblast cell migration;GO:0060054//positive regulation of epithelial cell proliferation involved in wound healing;GO:0042493//response to drug;GO:0010628//positive regulation of gene expression;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:0001666//response to hypoxia;GO:0022617//extracellular matrix disassembly;GO:0006508//proteolysis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1902741//positive regulation of interferon-alpha secretion;GO:0035313//wound healing, spreading of epidermal cells;GO:0006606//protein import into nucleus;GO:0098586//cellular response to virus;GO:0050691//regulation of defense response to virus by host;GO:0060339//negative regulation of type I interferon-mediated signaling pathway;GO:0050679//positive regulation of epithelial cell proliferation" K01413//matrix metalloproteinase-12 (macrophage elastase) [EC:3.4.24.65] EDL24933.1//matrix metallopeptidase 12 [Mus musculus];NP_032631.3//macrophage metalloelastase isoform 1 preproprotein [Mus musculus] 71914 3776 4020.093252 11742.25703 1.546408869 1.23E-79 Up 7.93E-84 GO:0009986//cell surface;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane GO:0046872//metal ion binding;GO:0004872//receptor activity GO:1901998//toxin transport;GO:0022414//reproductive process K20909//anthrax toxin receptor NP_598499.1//anthrax toxin receptor 2 precursor [Mus musculus] 14229 3884 1341.132237 4034.969853 1.589106399 1.38E-63 Up 1.78E-67 GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005737//cytoplasm GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0031072//heat shock protein binding;GO:0005528//FK506 binding GO:0061077//chaperone-mediated protein folding K09571//FK506-binding protein 4/5 [EC:5.2.1.8] NP_034350.1//peptidyl-prolyl cis-trans isomerase FKBP5 [Mus musculus] 18576 5314 259.5738394 789.0807749 1.604027999 1.04E-33 Up 3.36E-37 GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0032045//guanyl-nucleotide exchange factor complex "GO:0043422//protein kinase B binding;GO:0046872//metal ion binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity" GO:0007165//signal transduction;GO:0001525//angiogenesis;GO:0007162//negative regulation of cell adhesion;GO:0016525//negative regulation of angiogenesis;GO:0031018//endocrine pancreas development;GO:0050796//regulation of insulin secretion;GO:0042593//glucose homeostasis;GO:0032869//cellular response to insulin stimulus;GO:0006198//cAMP catabolic process;GO:0050995//negative regulation of lipid catabolic process "K13296//cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]" "NP_035185.2//cGMP-inhibited 3',5'-cyclic phosphodiesterase B [Mus musculus]" 20692 2640 18.61576917 56.87459659 1.61125918 0.000661962 Up 9.72E-06 GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005622//intracellular;GO:0016363//nuclear matrix;GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix;GO:0009986//cell surface;GO:0031091//platelet alpha granule;GO:0005604//basement membrane;GO:0031092//platelet alpha granule membrane GO:0005518//collagen binding;GO:0005509//calcium ion binding;GO:0050840//extracellular matrix binding GO:0030324//lung development;GO:0034097//response to cytokine;GO:0042127//regulation of cell proliferation;GO:0032496//response to lipopolysaccharide;GO:0010595//positive regulation of endothelial cell migration;GO:0001503//ossification;GO:0009629//response to gravity;GO:0045471//response to ethanol;GO:0071363//cellular response to growth factor stimulus;GO:0048839//inner ear development;GO:0051384//response to glucocorticoid;GO:0033591//response to L-ascorbic acid;GO:0060348//bone development;GO:0001937//negative regulation of endothelial cell proliferation;GO:0007165//signal transduction;GO:0007507//heart development;GO:0016525//negative regulation of angiogenesis;GO:0042060//wound healing;GO:0043434//response to peptide hormone;GO:0051591//response to cAMP;GO:0043473//pigmentation;GO:0046686//response to cadmium ion;GO:0051592//response to calcium ion;GO:0010288//response to lead ion;GO:0022604//regulation of cell morphogenesis K10402//kinesin family member 20 NP_001277746.1//SPARC isoform 2 precursor [Mus musculus];NP_033268.1//SPARC precursor [Mus musculus] 71897 2285 50.52320483 154.5154252 1.612732808 1.27E-11 Up 4.11E-14 GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane GO:0030548//acetylcholine receptor regulator activity NA K08576//calpain-7 [EC:3.4.22.-] XP_021012669.1//ly6/PLAUR domain-containing protein 6B isoform X1 [Mus caroli] 380694 2709 5.172306288 17.13611066 1.728160087 0.001914953 Up 3.41E-05 GO:0005634//nucleus NA NA K06627//cyclin-A NP_001038995.1//cyclin-J-like protein [Mus musculus] 320253 1754 17.90008316 60.78506428 1.763750587 5.73E-07 Up 3.81E-09 GO:0005768//endosome;GO:0031901//early endosome membrane;GO:0016021//integral component of membrane;GO:0005764//lysosome;GO:0030659//cytoplasmic vesicle membrane GO:0008270//zinc ion binding;GO:0016740//transferase activity GO:0016567//protein ubiquitination;GO:0006897//endocytosis K10658//E3 ubiquitin-protein ligase MARCH3 [EC:2.3.2.27] NP_796089.1//E3 ubiquitin-protein ligase MARCH3 [Mus musculus] 14012 3216 23.43998695 80.93597433 1.787809326 2.62E-08 Up 1.39E-10 GO:0016021//integral component of membrane NA NA K06770//myelin protein zero XP_021063394.1//myelin protein zero-like protein 2 [Mus pahari] 12825 5564 23.41961362 85.24815712 1.863951372 2.49E-06 Up 1.89E-08 GO:0031012//extracellular matrix;GO:0005615//extracellular space;GO:0005581//collagen trimer;GO:0005586//collagen type III trimer;GO:0005578//proteinaceous extracellular matrix GO:0002020//protease binding;GO:0048407//platelet-derived growth factor binding;GO:0046872//metal ion binding;GO:0005201//extracellular matrix structural constituent;GO:0005178//integrin binding;GO:0046332//SMAD binding GO:0043588//skin development;GO:0034097//response to cytokine;GO:0030199//collagen fibril organization;GO:0001568//blood vessel development;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0018149//peptide cross-linking;GO:0021987//cerebral cortex development;GO:0007229//integrin-mediated signaling pathway;GO:0009612//response to mechanical stimulus;GO:0007507//heart development;GO:0042060//wound healing;GO:0060414//aorta smooth muscle tissue morphogenesis;GO:0048565//digestive tract development;GO:0007568//aging;GO:0071230//cellular response to amino acid stimulus;GO:0007160//cell-matrix adhesion;GO:0050777//negative regulation of immune response;GO:2001223//negative regulation of neuron migration;GO:0035025//positive regulation of Rho protein signal transduction;GO:0009314//response to radiation;GO:0097435//supramolecular fiber organization;GO:0001501//skeletal system development "K19720//collagen, type III, alpha" "BAD90325.1//mKIAA4231 protein, partial [Mus musculus]" 72565 4338 22.28735102 91.56538623 2.038577176 1.53E-10 Up 5.65E-13 GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0043293//apoptosome;GO:0005635//nuclear envelope;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm NA GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0097190//apoptotic signaling pathway;GO:0009411//response to UV;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:1901222//regulation of NIK/NF-kappaB signaling;GO:0050728//negative regulation of inflammatory response;GO:0043065//positive regulation of apoptotic process;GO:0042347//negative regulation of NF-kappaB import into nucleus;GO:0042307//positive regulation of protein import into nucleus K20478//golgin subfamily B member 1 "EDL26002.1//uveal autoantigen with coiled-coil domains and ankyrin repeats, isoform CRA_a [Mus musculus];EDL26004.1//uveal autoantigen with coiled-coil domains and ankyrin repeats, isoform CRA_c, partial [Mus musculus]" 19279 2508 5.647307253 23.64491608 2.06589499 4.38E-05 Up 4.48E-07 GO:0005615//extracellular space;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0005737//cytoplasm;GO:0005886//plasma membrane GO:0004725//protein tyrosine phosphatase activity;GO:0019901//protein kinase binding GO:0007399//nervous system development;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0030182//neuron differentiation;GO:0038128//ERBB2 signaling pathway;GO:0006470//protein dephosphorylation;GO:0001701//in utero embryonic development;GO:0010633//negative regulation of epithelial cell migration K04458//receptor-type tyrosine-protein phosphatase R [EC:3.1.3.48] CAA82958.1//protein-tyrosine-phosphatase [Mus musculus];XP_021060058.1//receptor-type tyrosine-protein phosphatase R isoform X3 [Mus pahari];NP_001155309.1//receptor-type tyrosine-protein phosphatase R isoform b [Mus musculus];NP_035347.1//receptor-type tyrosine-protein phosphatase R isoform a precursor [Mus musculus] 64818 1857 7.781352173 36.08859442 2.213450174 1.88E-06 Up 1.38E-08 GO:0005615//extracellular space;GO:0045095//keratin filament GO:0005198//structural molecule activity NA "K07605//type II keratin, basic" "NP_001008814.1//keratin, type II cuticular Hb1 [Rattus norvegicus]" 29863 5091 232.8634359 1199.889477 2.365345493 5.19E-12 Up 1.48E-14 NA NA NA "K18436//high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7 [EC:3.1.4.53]" "EDL93805.1//phosphodiesterase 7B, isoform CRA_b [Rattus norvegicus];EHH53362.1//hypothetical protein EGM_13990, partial [Macaca fascicularis]" 94219 3268 183.3111981 1513.934885 3.04593633 2.77E-19 Up 3.04E-22 GO:0043231//intracellular membrane-bounded organelle;GO:0016323//basolateral plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane GO:0005524//ATP binding;GO:0015095//magnesium ion transmembrane transporter activity GO:0015693//magnesium ion transport;GO:0010960//magnesium ion homeostasis K16302//metal transporter CNNM "EDL42018.1//cyclin M2, isoform CRA_a, partial [Mus musculus]" 63955 3309 35.22297829 407.9068463 3.533650915 1.80E-56 Up 3.50E-60 GO:0005654//nucleoplasm;GO:0030426//growth cone;GO:0005829//cytosol NA GO:0007399//nervous system development;GO:0007596//blood coagulation;GO:0051301//cell division;GO:0000082//G1/S transition of mitotic cell cycle;GO:0051726//regulation of cell cycle "K16628//collagen, type VII, alpha;K09528//DnaJ homolog subfamily C member 8" NP_001139759.1//CDK5 and ABL1 enzyme substrate 1 isoform 1 [Mus musculus];NP_071304.2//CDK5 and ABL1 enzyme substrate 1 isoform 2 [Mus musculus]