Table S1 up regulated KEGG pathways in the condition of WT versus Ctr1 KO MEFs Term Database ID Input_number Background_number Rich_factor P_Value Corrected P_Value Input Hyperlink Ribosome KEGG PATHWAY mmu03010 60 148 6.83 2.14E-20 5.80E-18 mmu:66480:Gm10020|mmu:11837:Gm9625|mmu:16898:Rps2-ps13|mmu:20084:Rps18|mmu:269261:Rpl12|mmu:22186:Gm7866|mmu:19942:Rpl27-ps1|mmu:20084:Gm11361|mmu:54127:Gm10443|mmu:16898:Gm5786|mmu:20115:Gm9493|mmu:19951:Gm7266|mmu:102634941:Rpl29|mmu:16898:Gm10420|mmu:269261:Gm11425|mmu:19921:Gm16238|mmu:19921:Rpl19-ps9|mmu:27176:Gm5619|mmu:20054:C630043F03Rik|mmu:66480:Rpl15|mmu:26961:Gm28911|mmu:102634941:Gm10709|mmu:16898:Gm6311|mmu:19941:Gm13268|mmu:27207:Gm6394|mmu:76846:Gm5905|mmu:20005:Gm5451|mmu:11837:Gm14165|mmu:66489:Gm10269|mmu:66475:Rps23-ps2|mmu:16898:Rps2|mmu:22121:Gm11478|mmu:19982:Rpl36a-ps1|mmu:66480:Gm4294|mmu:16785:Rpsa-ps9|mmu:68537:Mrpl13|mmu:268449:Gm3940|mmu:27367:Gm12816|mmu:268449:Gm3362|mmu:16898:Rps2-ps6|mmu:22121:Rpl13a-ps1|mmu:20042:Rps12-ps4|mmu:16785:Rpsa-ps12|mmu:67097:Rps10-ps1|mmu:319195:Gm6133|mmu:16898:RP23-410B24.5|mmu:76808:Rpl18-ps1|mmu:77721:Gm13328|mmu:20104:Gm8925|mmu:19941:Gm10136|mmu:20104:Rps6-ps1|mmu:68193:Gm12254|mmu:66480:Rpl15-ps2|mmu:66480:Rpl15-ps3|mmu:27367:Gm5879|mmu:11837:Gm8730|mmu:16898:Gm5921|mmu:225215:Gm6457|mmu:27398:Mrpl2|mmu:26961:Rpl8 http://www.genome.jp/kegg-bin/show_pathway?mmu03010/mmu:76808%09red/mmu:76846%09red/mmu:19921%09red/mmu:27367%09red/mmu:67097%09red/mmu:268449%09red/mmu:319195%09red/mmu:19941%09red/mmu:20115%09red/mmu:20084%09red/mmu:19982%09red/mmu:27176%09red/mmu:68537%09red/mmu:20042%09red/mmu:26961%09red/mmu:22186%09red/mmu:16898%09red/mmu:66475%09red/mmu:269261%09red/mmu:19942%09red/mmu:102634941%09red/mmu:11837%09red/mmu:16785%09red/mmu:68193%09red/mmu:22121%09red/mmu:19951%09red/mmu:66480%09red/mmu:66489%09red/mmu:27207%09red/mmu:20104%09red/mmu:20054%09red/mmu:54127%09red/mmu:77721%09red/mmu:27398%09red/mmu:20005%09red/mmu:225215%09red Steroid biosynthesis KEGG PATHWAY mmu00100 9 19 7.98 0.000132375 0.017936804 mmu:13360:Dhcr7|mmu:13121:Cyp51|mmu:16987:Lss|mmu:66234:Msmo1|mmu:16987:4930483K19Rik|mmu:18194:Nsdhl|mmu:223920:Soat2|mmu:20775:Sqle|mmu:74754:Dhcr24 http://www.genome.jp/kegg-bin/show_pathway?mmu00100/mmu:13360%09red/mmu:16987%09red/mmu:13121%09red/mmu:18194%09red/mmu:74754%09red/mmu:20775%09red/mmu:223920%09red/mmu:66234%09red Protein digestion and absorption KEGG PATHWAY mmu04974 19 90 3.56 0.000429972 0.038840792 mmu:12826:Col4a1|mmu:12842:Col1a1|mmu:12843:Col1a2|mmu:20532:Slc3a1|mmu:53867:Col5a3|mmu:17254:Slc3a2|mmu:12816:Col12a1|mmu:12827:Col4a2|mmu:12830:Col4a5|mmu:12824:Col2a1|mmu:12815:Col11a2|mmu:20514:Slc1a5|mmu:373864:Col27a1|mmu:72472:Slc16a10|mmu:16529:Kcnk5|mmu:12836:Col7a1|mmu:12832:Col5a2|mmu:12825:Col3a1|mmu:68553:Col6a4 http://www.genome.jp/kegg-bin/show_pathway?mmu04974/mmu:12843%09red/mmu:12842%09red/mmu:373864%09red/mmu:20532%09red/mmu:12815%09red/mmu:12816%09red/mmu:17254%09red/mmu:12832%09red/mmu:12830%09red/mmu:68553%09red/mmu:12825%09red/mmu:16529%09red/mmu:12827%09red/mmu:12826%09red/mmu:12836%09red/mmu:72472%09red/mmu:20514%09red/mmu:12824%09red/mmu:53867%09red Selenocompound metabolism KEGG PATHWAY mmu00450 6 17 5.95 0.005731675 0.323436984 mmu:216443:Mars|mmu:23972:Papss2|mmu:107869:Cth|mmu:70266:Kyat1|mmu:229905:Kyat3|mmu:232223:Txnrd3 http://www.genome.jp/kegg-bin/show_pathway?mmu00450/mmu:107869%09red/mmu:70266%09red/mmu:216443%09red/mmu:229905%09red/mmu:23972%09red/mmu:232223%09red Proteoglycans in cancer KEGG PATHWAY mmu05205 29 208 2.35 0.005967472 0.323436984 mmu:18176:Nras|mmu:21844:Tiam1|mmu:13345:Twist2|mmu:17869:Myc|mmu:15529:Sdc2|mmu:22417:Wnt4|mmu:14173:Gm43439|mmu:12843:Col1a2|mmu:16000:Igf1|mmu:11465:Gm8399|mmu:22059:Trp53|mmu:57265:Fzd2|mmu:68794:Flnc|mmu:11735:Ank2|mmu:22410:Wnt10b|mmu:234779:Plcg2|mmu:13649:Egfr|mmu:14173:Fgf2|mmu:21859:Timp3|mmu:22339:Vegfa|mmu:14182:Fgfr1|mmu:29857:Mapk12|mmu:14362:Fzd1|mmu:20104:Gm8925|mmu:14365:Fzd3|mmu:20104:Rps6-ps1|mmu:13345:Gm29100|mmu:12842:Col1a1|mmu:14182:Gm16159 http://www.genome.jp/kegg-bin/show_pathway?mmu05205/mmu:14173%09red/mmu:22339%09red/mmu:21844%09red/mmu:12843%09red/mmu:12842%09red/mmu:68794%09red/mmu:14362%09red/mmu:18176%09red/mmu:14365%09red/mmu:15529%09red/mmu:11735%09red/mmu:13345%09red/mmu:234779%09red/mmu:16000%09red/mmu:11465%09red/mmu:21859%09red/mmu:57265%09red/mmu:22410%09red/mmu:22417%09red/mmu:14182%09red/mmu:20104%09red/mmu:22059%09red/mmu:17869%09red/mmu:29857%09red/mmu:13649%09red PI3K-Akt signaling pathway KEGG PATHWAY mmu04151 43 350 2.07 0.007696106 0.347607464 mmu:18176:Nras|mmu:26427:Creb3l1|mmu:14709:Gng8|mmu:16186:Gm20489|mmu:17869:Myc|mmu:13685:Eif4ebp1|mmu:12824:Col2a1|mmu:16186:Il2rg|mmu:12827:Col4a2|mmu:56636:Fgf21|mmu:74551:Pck2|mmu:12826:Col4a1|mmu:78134:Lpar4|mmu:14173:Gm43439|mmu:74747:Ddit4|mmu:12843:Col1a2|mmu:16000:Igf1|mmu:64337:Gng13|mmu:13638:Efna3|mmu:16421:Itgb7|mmu:22059:Trp53|mmu:18049:Ngf|mmu:320910:Itgb8|mmu:11911:Atf4|mmu:12830:Col4a5|mmu:13638:Gm15998|mmu:21827:Thbs3|mmu:14708:Gng7|mmu:13649:Egfr|mmu:14173:Fgf2|mmu:22339:Vegfa|mmu:14176:Fgf5|mmu:14182:Fgfr1|mmu:18591:Pdgfb|mmu:20104:Gm8925|mmu:20104:Rps6-ps1|mmu:14702:Gng2|mmu:16404:Itga7|mmu:12842:Col1a1|mmu:14182:Gm16159|mmu:14745:Lpar1|mmu:21923:Tnc|mmu:68553:Col6a4 http://www.genome.jp/kegg-bin/show_pathway?mmu04151/mmu:13638%09red/mmu:78134%09red/mmu:320910%09red/mmu:14173%09red/mmu:16404%09red/mmu:22339%09red/mmu:13685%09red/mmu:21827%09red/mmu:21923%09red/mmu:12843%09red/mmu:12842%09red/mmu:14182%09red/mmu:18176%09red/mmu:22059%09red/mmu:56636%09red/mmu:16421%09red/mmu:68553%09red/mmu:12824%09red/mmu:12827%09red/mmu:12826%09red/mmu:14708%09red/mmu:14709%09red/mmu:14702%09red/mmu:14745%09red/mmu:16000%09red/mmu:18591%09red/mmu:64337%09red/mmu:14176%09red/mmu:16186%09red/mmu:18049%09red/mmu:26427%09red/mmu:20104%09red/mmu:74747%09red/mmu:12830%09red/mmu:17869%09red/mmu:11911%09red/mmu:74551%09red/mmu:13649%09red GABAergic synapse KEGG PATHWAY mmu04727 15 89 2.84 0.010285956 0.379734038 mmu:12286:Gm16183|mmu:64337:Gng13|mmu:104111:Adcy3|mmu:14709:Gng8|mmu:14702:Gng2|mmu:432530:Adcy1|mmu:14708:Gng7|mmu:227120:Plcl1|mmu:14681:Gnao1|mmu:12288:Cacna1c|mmu:12287:Cacna1b|mmu:14677:Gnai1|mmu:14404:Gabre|mmu:57138:Slc12a5|mmu:105727:Slc38a1 http://www.genome.jp/kegg-bin/show_pathway?mmu04727/mmu:12287%09red/mmu:14708%09red/mmu:14709%09red/mmu:14404%09red/mmu:57138%09red/mmu:104111%09red/mmu:14681%09red/mmu:227120%09red/mmu:12288%09red/mmu:432530%09red/mmu:105727%09red/mmu:64337%09red/mmu:14702%09red/mmu:12286%09red/mmu:14677%09red Melanogenesis KEGG PATHWAY mmu04916 16 99 2.72 0.011488253 0.379734038 mmu:22417:Wnt4|mmu:18176:Nras|mmu:14677:Gnai1|mmu:16842:Lef1|mmu:26427:Creb3l1|mmu:14362:Fzd1|mmu:104111:Adcy3|mmu:432530:Adcy1|mmu:57265:Fzd2|mmu:21414:Tcf7|mmu:22410:Wnt10b|mmu:14681:Gnao1|mmu:16842:Gm43352|mmu:12313:Gm15720|mmu:14365:Fzd3|mmu:13614:Edn1 http://www.genome.jp/kegg-bin/show_pathway?mmu04916/mmu:12313%09red/mmu:57265%09red/mmu:22410%09red/mmu:22417%09red/mmu:14677%09red/mmu:432530%09red/mmu:104111%09red/mmu:14681%09red/mmu:18176%09red/mmu:14365%09red/mmu:21414%09red/mmu:16842%09red/mmu:13614%09red/mmu:14362%09red/mmu:26427%09red Aminoacyl-tRNA biosynthesis KEGG PATHWAY mmu00970 12 66 3.06 0.012611094 0.379734038 mmu:27267:Cars|mmu:107271:Yars|mmu:107045:Lars|mmu:104458:Rars|mmu:234734:Aars|mmu:70223:Nars|mmu:110960:Tars|mmu:20226:Sars|mmu:224805:Aars2|mmu:353172:Gars|mmu:216443:Mars|mmu:22375:Wars http://www.genome.jp/kegg-bin/show_pathway?mmu00970/mmu:224805%09red/mmu:216443%09red/mmu:353172%09red/mmu:110960%09red/mmu:107045%09red/mmu:22375%09red/mmu:70223%09red/mmu:20226%09red/mmu:234734%09red/mmu:27267%09red/mmu:107271%09red/mmu:104458%09red MAPK signaling pathway KEGG PATHWAY mmu04010 32 254 2.12 0.014414853 0.379904647 mmu:18176:Nras|mmu:17346:Mknk1|mmu:211429:Gm28042|mmu:56636:Fgf21|mmu:12287:Cacna1b|mmu:12295:Cacnb1|mmu:53859:Map3k14|mmu:14173:Gm43439|mmu:66513:Tab1|mmu:12286:Gm16183|mmu:13197:E230016M11Rik|mmu:14182:Fgfr1|mmu:102626:Mapkapk3|mmu:20112:Rps6ka2|mmu:22059:Trp53|mmu:13197:Gadd45a|mmu:211429:Pla2g4b|mmu:18049:Ngf|mmu:11911:Atf4|mmu:68794:Flnc|mmu:12288:Cacna1c|mmu:71751:Map3k13|mmu:216869:Arrb2|mmu:17869:Myc|mmu:13649:Egfr|mmu:12293:Cacna2d1|mmu:14173:Fgf2|mmu:14176:Fgf5|mmu:12291:Cacna1g|mmu:29857:Mapk12|mmu:18591:Pdgfb|mmu:14182:Gm16159 http://www.genome.jp/kegg-bin/show_pathway?mmu04010/mmu:14182%09red/mmu:14173%09red/mmu:14176%09red/mmu:102626%09red/mmu:13197%09red/mmu:12295%09red/mmu:12293%09red/mmu:68794%09red/mmu:12291%09red/mmu:18176%09red/mmu:56636%09red/mmu:66513%09red/mmu:17346%09red/mmu:53859%09red/mmu:18591%09red/mmu:12286%09red/mmu:71751%09red/mmu:12287%09red/mmu:216869%09red/mmu:18049%09red/mmu:20112%09red/mmu:12288%09red/mmu:22059%09red/mmu:17869%09red/mmu:11911%09red/mmu:29857%09red/mmu:13649%09red/mmu:211429%09red Hedgehog signaling pathway KEGG PATHWAY mmu04340 9 44 3.45 0.015745429 0.379904647 mmu:68525:Evc2|mmu:59056:Evc|mmu:57810:Cdon|mmu:27373:Gm16059|mmu:14633:Gli2|mmu:27373:Csnk1e|mmu:216869:Arrb2|mmu:14725:Lrp2|mmu:14451:Gas1 http://www.genome.jp/kegg-bin/show_pathway?mmu04340/mmu:216869%09red/mmu:14725%09red/mmu:57810%09red/mmu:68525%09red/mmu:59056%09red/mmu:14633%09red/mmu:27373%09red/mmu:14451%09red Prostate cancer KEGG PATHWAY mmu05215 14 89 2.65 0.020863336 0.379904647 mmu:13649:Egfr|mmu:11835:Ar|mmu:18176:Nras|mmu:26427:Creb3l1|mmu:14182:Fgfr1|mmu:22059:Trp53|mmu:18591:Pdgfb|mmu:21414:Tcf7|mmu:11911:Atf4|mmu:16842:Lef1|mmu:14870:Gstp1|mmu:16842:Gm43352|mmu:14182:Gm16159|mmu:16000:Igf1 http://www.genome.jp/kegg-bin/show_pathway?mmu05215/mmu:18591%09red/mmu:16000%09red/mmu:26427%09red/mmu:14182%09red/mmu:14870%09red/mmu:11835%09red/mmu:18176%09red/mmu:22059%09red/mmu:21414%09red/mmu:11911%09red/mmu:13649%09red/mmu:16842%09red Terpenoid backbone biosynthesis KEGG PATHWAY mmu00900 6 24 4.21 0.021570545 0.379904647 mmu:17855:Mvk|mmu:110196:Fdps|mmu:319554:Gm13502|mmu:110460:Acat2|mmu:192156:Mvd|mmu:110196:Gm3571 http://www.genome.jp/kegg-bin/show_pathway?mmu00900/mmu:110460%09red/mmu:17855%09red/mmu:319554%09red/mmu:192156%09red/mmu:110196%09red Basal cell carcinoma KEGG PATHWAY mmu05217 10 55 3.06 0.021673802 0.379904647 mmu:22417:Wnt4|mmu:57265:Fzd2|mmu:14633:Gli2|mmu:22059:Trp53|mmu:14362:Fzd1|mmu:21414:Tcf7|mmu:22410:Wnt10b|mmu:16842:Lef1|mmu:16842:Gm43352|mmu:14365:Fzd3 http://www.genome.jp/kegg-bin/show_pathway?mmu05217/mmu:57265%09red/mmu:22410%09red/mmu:22417%09red/mmu:14362%09red/mmu:14365%09red/mmu:14633%09red/mmu:21414%09red/mmu:16842%09red/mmu:22059%09red Melanoma KEGG PATHWAY mmu05218 12 72 2.81 0.021806879 0.379904647 mmu:12578:Cdkn2a|mmu:13649:Egfr|mmu:14173:Fgf2|mmu:14173:Gm43439|mmu:18176:Nras|mmu:14176:Fgf5|mmu:14182:Fgfr1|mmu:22059:Trp53|mmu:18591:Pdgfb|mmu:56636:Fgf21|mmu:14182:Gm16159|mmu:16000:Igf1 http://www.genome.jp/kegg-bin/show_pathway?mmu05218/mmu:18176%09red/mmu:14182%09red/mmu:14173%09red/mmu:16000%09red/mmu:12578%09red/mmu:22059%09red/mmu:56636%09red/mmu:14176%09red/mmu:18591%09red/mmu:13649%09red Dilated cardiomyopathy KEGG PATHWAY mmu05414 14 90 2.62 0.022508706 0.379904647 mmu:12293:Cacna2d1|mmu:326618:Gm7809|mmu:11465:Gm8399|mmu:16421:Itgb7|mmu:432530:Adcy1|mmu:22004:Tpm2|mmu:16000:Igf1|mmu:320910:Itgb8|mmu:24051:Sgcb|mmu:12288:Cacna1c|mmu:12295:Cacnb1|mmu:16404:Itga7|mmu:104111:Adcy3|mmu:21954:Tnni3 http://www.genome.jp/kegg-bin/show_pathway?mmu05414/mmu:12295%09red/mmu:22004%09red/mmu:12293%09red/mmu:432530%09red/mmu:326618%09red/mmu:16000%09red/mmu:12288%09red/mmu:21954%09red/mmu:320910%09red/mmu:16421%09red/mmu:11465%09red/mmu:104111%09red/mmu:24051%09red/mmu:16404%09red Rap1 signaling pathway KEGG PATHWAY mmu04015 27 215 2.12 0.023831657 0.379904647 mmu:18176:Nras|mmu:21844:Tiam1|mmu:56636:Fgf21|mmu:14677:Gnai1|mmu:106952:Arap3|mmu:78134:Lpar4|mmu:14173:Gm43439|mmu:104111:Adcy3|mmu:16000:Igf1|mmu:11465:Gm8399|mmu:13638:Efna3|mmu:432530:Adcy1|mmu:18049:Ngf|mmu:13638:Gm15998|mmu:12313:Gm15720|mmu:75292:Prkd3|mmu:13649:Egfr|mmu:14173:Fgf2|mmu:22339:Vegfa|mmu:70549:Tln2|mmu:14176:Fgf5|mmu:14182:Fgfr1|mmu:29857:Mapk12|mmu:18591:Pdgfb|mmu:14681:Gnao1|mmu:14182:Gm16159|mmu:14745:Lpar1 http://www.genome.jp/kegg-bin/show_pathway?mmu04015/mmu:12313%09red/mmu:13638%09red/mmu:78134%09red/mmu:432530%09red/mmu:14681%09red/mmu:22339%09red/mmu:21844%09red/mmu:75292%09red/mmu:106952%09red/mmu:14182%09red/mmu:104111%09red/mmu:18176%09red/mmu:56636%09red/mmu:14173%09red/mmu:14745%09red/mmu:14677%09red/mmu:16000%09red/mmu:18591%09red/mmu:11465%09red/mmu:14176%09red/mmu:18049%09red/mmu:70549%09red/mmu:29857%09red/mmu:13649%09red Morphine addiction KEGG PATHWAY mmu05032 14 93 2.54 0.028027314 0.38129948 mmu:12286:Gm16183|mmu:64337:Gng13|mmu:104111:Adcy3|mmu:14709:Gng8|mmu:432530:Adcy1|mmu:14708:Gng7|mmu:18584:Pde8a|mmu:14681:Gnao1|mmu:14702:Gng2|mmu:12287:Cacna1b|mmu:216869:Arrb2|mmu:14677:Gnai1|mmu:14404:Gabre|mmu:18576:Pde3b http://www.genome.jp/kegg-bin/show_pathway?mmu05032/mmu:14708%09red/mmu:216869%09red/mmu:14404%09red/mmu:432530%09red/mmu:104111%09red/mmu:14681%09red/mmu:12287%09red/mmu:18584%09red/mmu:14702%09red/mmu:14709%09red/mmu:64337%09red/mmu:14677%09red/mmu:12286%09red/mmu:18576%09red Signaling pathways regulating pluripotency of stem cells KEGG PATHWAY mmu04550 19 140 2.29 0.028316031 0.38129948 mmu:22417:Wnt4|mmu:18176:Nras|mmu:17268:Meis1|mmu:14173:Fgf2|mmu:14173:Gm43439|mmu:20674:Sox2|mmu:14182:Fgfr1|mmu:29857:Mapk12|mmu:14362:Fzd1|mmu:57265:Fzd2|mmu:18423:Otx1|mmu:17869:Myc|mmu:55994:Smad9|mmu:22410:Wnt10b|mmu:13984:Esx1|mmu:14365:Fzd3|mmu:14182:Gm16159|mmu:16000:Igf1|mmu:16324:Inhbb http://www.genome.jp/kegg-bin/show_pathway?mmu04550/mmu:57265%09red/mmu:16000%09red/mmu:22417%09red/mmu:14182%09red/mmu:17268%09red/mmu:14362%09red/mmu:18176%09red/mmu:14365%09red/mmu:14173%09red/mmu:55994%09red/mmu:18423%09red/mmu:17869%09red/mmu:22410%09red/mmu:13984%09red/mmu:29857%09red/mmu:20674%09red/mmu:16324%09red Retrograde endocannabinoid signaling KEGG PATHWAY mmu04723 15 103 2.45 0.029640133 0.38129948 mmu:12286:Gm16183|mmu:72961:Slc17a7|mmu:104111:Adcy3|mmu:14709:Gng8|mmu:29857:Mapk12|mmu:14702:Gng2|mmu:432530:Adcy1|mmu:53623:Gria3|mmu:14708:Gng7|mmu:14681:Gnao1|mmu:12288:Cacna1c|mmu:12287:Cacna1b|mmu:14677:Gnai1|mmu:14404:Gabre|mmu:64337:Gng13 http://www.genome.jp/kegg-bin/show_pathway?mmu04723/mmu:12287%09red/mmu:14708%09red/mmu:14709%09red/mmu:14404%09red/mmu:432530%09red/mmu:104111%09red/mmu:14681%09red/mmu:12288%09red/mmu:72961%09red/mmu:14702%09red/mmu:53623%09red/mmu:64337%09red/mmu:29857%09red/mmu:12286%09red/mmu:14677%09red One carbon pool by folate KEGG PATHWAY mmu00670 5 19 4.43 0.02968643 0.38129948 mmu:108037:Shmt2|mmu:216188:Aldh1l2|mmu:20425:Shmt1|mmu:270685:Mthfd1l|mmu:17768:Mthfd2 http://www.genome.jp/kegg-bin/show_pathway?mmu00670/mmu:20425%09red/mmu:270685%09red/mmu:108037%09red/mmu:216188%09red/mmu:17768%09red Cholinergic synapse KEGG PATHWAY mmu04725 16 113 2.39 0.030954201 0.38129948 mmu:12326:Camk4|mmu:18176:Nras|mmu:64337:Gng13|mmu:26427:Creb3l1|mmu:14709:Gng8|mmu:14702:Gng2|mmu:432530:Adcy1|mmu:14708:Gng7|mmu:11911:Atf4|mmu:16520:Kcnj4|mmu:14681:Gnao1|mmu:12288:Cacna1c|mmu:12287:Cacna1b|mmu:14677:Gnai1|mmu:104111:Adcy3|mmu:12286:Gm16183 http://www.genome.jp/kegg-bin/show_pathway?mmu04725/mmu:12287%09red/mmu:14708%09red/mmu:14709%09red/mmu:14677%09red/mmu:432530%09red/mmu:104111%09red/mmu:14681%09red/mmu:18176%09red/mmu:12288%09red/mmu:12326%09red/mmu:12286%09red/mmu:11911%09red/mmu:64337%09red/mmu:14702%09red/mmu:16520%09red/mmu:26427%09red HTLV-I infection KEGG PATHWAY mmu05166 34 295 1.94 0.034100732 0.395525654 mmu:18176:Nras|mmu:13653:Egr1|mmu:16186:Gm20489|mmu:110196:Fdps|mmu:15018:H2-Q7|mmu:17869:Myc|mmu:22410:Wnt10b|mmu:15040:H2-T23|mmu:15015:Gm11131|mmu:16186:Il2rg|mmu:110196:Gm3571|mmu:17702:Msx2|mmu:53859:Map3k14|mmu:22417:Wnt4|mmu:237336:Tbpl1|mmu:104111:Adcy3|mmu:110557:H2-Q6|mmu:15015:H2-Q4|mmu:11910:Atf3|mmu:16818:Lck|mmu:22059:Trp53|mmu:432530:Adcy1|mmu:11911:Atf4|mmu:14963:H2-Bl|mmu:13654:Egr2|mmu:14991:H2-M3|mmu:12578:Cdkn2a|mmu:57265:Fzd2|mmu:70549:Tln2|mmu:14362:Fzd1|mmu:18591:Pdgfb|mmu:14365:Fzd3|mmu:15007:H2-K2|mmu:14961:H2-Ab1 http://www.genome.jp/kegg-bin/show_pathway?mmu05166/mmu:432530%09red/mmu:17702%09red/mmu:12578%09red/mmu:237336%09red/mmu:110196%09red/mmu:15040%09red/mmu:14991%09red/mmu:15018%09red/mmu:15015%09red/mmu:104111%09red/mmu:14362%09red/mmu:18176%09red/mmu:16818%09red/mmu:14365%09red/mmu:13653%09red/mmu:53859%09red/mmu:13654%09red/mmu:110557%09red/mmu:14963%09red/mmu:18591%09red/mmu:14961%09red/mmu:16186%09red/mmu:57265%09red/mmu:22410%09red/mmu:22417%09red/mmu:15007%09red/mmu:22059%09red/mmu:17869%09red/mmu:11910%09red/mmu:11911%09red/mmu:70549%09red Glutamatergic synapse KEGG PATHWAY mmu04724 16 115 2.34 0.035028102 0.395525654 mmu:211429:Gm28042|mmu:72961:Slc17a7|mmu:104111:Adcy3|mmu:14709:Gng8|mmu:64337:Gng13|mmu:12288:Cacna1c|mmu:432530:Adcy1|mmu:211429:Pla2g4b|mmu:53623:Gria3|mmu:14708:Gng7|mmu:14809:Grik5|mmu:14681:Gnao1|mmu:14702:Gng2|mmu:14677:Gnai1|mmu:105727:Slc38a1|mmu:12286:Gm16183 http://www.genome.jp/kegg-bin/show_pathway?mmu04724/mmu:14708%09red/mmu:14709%09red/mmu:14809%09red/mmu:14677%09red/mmu:432530%09red/mmu:104111%09red/mmu:14681%09red/mmu:53623%09red/mmu:12288%09red/mmu:72961%09red/mmu:14702%09red/mmu:105727%09red/mmu:64337%09red/mmu:211429%09red/mmu:12286%09red Biosynthesis of amino acids KEGG PATHWAY mmu01230 12 79 2.56 0.037912079 0.410966933 mmu:236539:Gm9347|mmu:12036:Bcat2|mmu:108682:Gpt2|mmu:56454:Aldh18a1|mmu:20425:Shmt1|mmu:107272:Psat1|mmu:107869:Cth|mmu:108037:Shmt2|mmu:109900:Asl|mmu:11429:Aco2|mmu:12035:Bcat1|mmu:209027:Pycr1 http://www.genome.jp/kegg-bin/show_pathway?mmu01230/mmu:107869%09red/mmu:11429%09red/mmu:108037%09red/mmu:56454%09red/mmu:108682%09red/mmu:20425%09red/mmu:109900%09red/mmu:12035%09red/mmu:12036%09red/mmu:209027%09red/mmu:107272%09red/mmu:236539%09red Thyroid cancer KEGG PATHWAY mmu05216 6 29 3.49 0.043022554 0.448427394 mmu:18176:Nras|mmu:22059:Trp53|mmu:21414:Tcf7|mmu:17869:Myc|mmu:16842:Lef1|mmu:16842:Gm43352 http://www.genome.jp/kegg-bin/show_pathway?mmu05216/mmu:21414%09red/mmu:18176%09red/mmu:17869%09red/mmu:22059%09red/mmu:16842%09red EGFR tyrosine kinase inhibitor resistance KEGG PATHWAY mmu01521 12 82 2.47 0.046883826 0.470574696 mmu:13649:Egfr|mmu:14173:Fgf2|mmu:14173:Gm43439|mmu:18176:Nras|mmu:211323:Nrg1|mmu:18591:Pdgfb|mmu:20104:Gm8925|mmu:20104:Rps6-ps1|mmu:22339:Vegfa|mmu:13685:Eif4ebp1|mmu:16000:Igf1|mmu:234779:Plcg2 http://www.genome.jp/kegg-bin/show_pathway?mmu01521/mmu:16000%09red/mmu:234779%09red/mmu:14173%09red/mmu:18176%09red/mmu:22339%09red/mmu:18591%09red/mmu:13685%09red/mmu:211323%09red/mmu:13649%09red/mmu:20104%09red