P-value,Source,Term id,Term name,Term size,Query size,Intersection size,Precision,Recall 0.049614216196929836,CORUM,CORUM:5198,"CBP-RARA-RXRA-DNA complex, ligand stimulated",3,23,2,0.08695652173913043,0.6666666666666666 0.049614216196929836,CORUM,CORUM:6586,VEcad-VEGFR complex,3,23,2,0.08695652173913043,0.6666666666666666 1.3207861971554524e-18,GO:BP,GO:0009719,response to endogenous stimulus,1696,48,32,0.6666666666666666,0.018867924528301886 3.8370502276696623e-17,GO:BP,GO:0070887,cellular response to chemical stimulus,3419,48,39,0.8125,0.011406844106463879 1.0307509080056735e-15,GO:BP,GO:0071495,cellular response to endogenous stimulus,1431,48,28,0.5833333333333334,0.019566736547868623 2.2723641859057123e-15,GO:BP,GO:0071310,cellular response to organic substance,2797,48,35,0.7291666666666666,0.012513407222023596 3.400652517718406e-15,GO:BP,GO:0042221,response to chemical,4808,48,42,0.875,0.008735440931780365 1.1263639573773444e-14,GO:BP,GO:0010033,response to organic substance,3433,48,37,0.7708333333333334,0.01077774541217594 1.637970380363119e-14,GO:BP,GO:1901700,response to oxygen-containing compound,1755,48,29,0.6041666666666666,0.016524216524216526 3.661764963314134e-14,GO:BP,GO:0023052,signaling,6814,48,46,0.9583333333333334,0.0067508071617258586 4.01588110677893e-14,GO:BP,GO:0007154,cell communication,6828,48,46,0.9583333333333334,0.006736965436438196 1.1233746871573281e-13,GO:BP,GO:1901701,cellular response to oxygen-containing compound,1241,48,25,0.5208333333333334,0.020145044319097503 1.2058857329918277e-13,GO:BP,GO:0014070,response to organic cyclic compound,977,48,23,0.4791666666666667,0.02354145342886387 1.406488791258653e-12,GO:BP,GO:0008283,cell population proliferation,2069,48,29,0.6041666666666666,0.01401643305944901 3.984864307616738e-12,GO:BP,GO:0042127,regulation of cell population proliferation,1779,48,27,0.5625,0.01517706576728499 6.624710125661541e-12,GO:BP,GO:0065008,regulation of biological quality,4133,48,37,0.7708333333333334,0.008952334865714976 1.043039791723761e-11,GO:BP,GO:0071407,cellular response to organic cyclic compound,591,48,18,0.375,0.030456852791878174 1.3944703061896814e-11,GO:BP,GO:0010646,regulation of cell communication,3659,48,35,0.7291666666666666,0.0095654550423613 1.9736920037322587e-11,GO:BP,GO:0023051,regulation of signaling,3699,48,35,0.7291666666666666,0.009462016761286834 2.3373895775305724e-11,GO:BP,GO:0006811,ion transport,1730,48,26,0.5416666666666666,0.015028901734104046 2.4506472056198625e-11,GO:BP,GO:0003008,system process,2303,48,29,0.6041666666666666,0.012592270950933565 6.530128519852217e-11,GO:BP,GO:0007267,cell-cell signaling,1806,48,26,0.5416666666666666,0.014396456256921373 7.673927317734137e-11,GO:BP,GO:0043410,positive regulation of MAPK cascade,560,48,17,0.3541666666666667,0.030357142857142857 9.525830637900636e-11,GO:BP,GO:0071417,cellular response to organonitrogen compound,672,48,18,0.375,0.026785714285714284 1.9665151338532252e-10,GO:BP,GO:0033993,response to lipid,944,48,20,0.4166666666666667,0.0211864406779661 2.2680236188915264e-10,GO:BP,GO:0010243,response to organonitrogen compound,1087,48,21,0.4375,0.019319227230910764 3.651403089210701e-10,GO:BP,GO:1901699,cellular response to nitrogen compound,727,48,18,0.375,0.024759284731774415 4.920079534173939e-10,GO:BP,GO:0032496,response to lipopolysaccharide,348,48,14,0.2916666666666667,0.040229885057471264 6.592092446515696e-10,GO:BP,GO:0070374,positive regulation of ERK1 and ERK2 cascade,214,48,12,0.25,0.056074766355140186 7.587116347438819e-10,GO:BP,GO:0042592,homeostatic process,2003,48,26,0.5416666666666666,0.012980529206190713 9.828110933616696e-10,GO:BP,GO:1901698,response to nitrogen compound,1172,48,21,0.4375,0.017918088737201365 1.1760521456913936e-09,GO:BP,GO:0002237,response to molecule of bacterial origin,371,48,14,0.2916666666666667,0.03773584905660377 1.50352436941714e-09,GO:BP,GO:0008015,blood circulation,565,48,16,0.3333333333333333,0.02831858407079646 1.6295925423049248e-09,GO:BP,GO:0007165,signal transduction,6291,48,41,0.8541666666666666,0.0065172468605945 1.7429636314071209e-09,GO:BP,GO:1902531,regulation of intracellular signal transduction,1883,48,25,0.5208333333333334,0.013276686139139671 3.222898937373087e-09,GO:BP,GO:0050896,response to stimulus,9430,48,47,0.9791666666666666,0.004984093319194061 4.223458108275215e-09,GO:BP,GO:0070371,ERK1 and ERK2 cascade,324,48,13,0.2708333333333333,0.040123456790123455 4.301962565351634e-09,GO:BP,GO:0051716,cellular response to stimulus,7777,48,44,0.9166666666666666,0.005657708628005658 5.074110044526672e-09,GO:BP,GO:0043269,regulation of ion transport,726,48,17,0.3541666666666667,0.023415977961432508 5.230440350449405e-09,GO:BP,GO:0008284,positive regulation of cell population proliferation,984,48,19,0.3958333333333333,0.019308943089430895 6.662602832576177e-09,GO:BP,GO:0035556,intracellular signal transduction,2854,48,29,0.6041666666666666,0.010161177295024528 1.0521432555130924e-08,GO:BP,GO:0043408,regulation of MAPK cascade,760,48,17,0.3541666666666667,0.02236842105263158 1.229126999180922e-08,GO:BP,GO:0003013,circulatory system process,649,48,16,0.3333333333333333,0.02465331278890601 1.3070678547009619e-08,GO:BP,GO:0045937,positive regulation of phosphate metabolic process,1184,48,20,0.4166666666666667,0.016891891891891893 1.3070678547009619e-08,GO:BP,GO:0010562,positive regulation of phosphorus metabolic process,1184,48,20,0.4166666666666667,0.016891891891891893 1.313836585277562e-08,GO:BP,GO:0048584,positive regulation of response to stimulus,2476,48,27,0.5625,0.010904684975767368 1.5158696249833598e-08,GO:BP,GO:0071868,cellular response to monoamine stimulus,103,48,9,0.1875,0.08737864077669903 1.5158696249833598e-08,GO:BP,GO:0071870,cellular response to catecholamine stimulus,103,48,9,0.1875,0.08737864077669903 1.662756141667408e-08,GO:BP,GO:0051049,regulation of transport,1887,48,24,0.5,0.012718600953895072 1.7611606873038188e-08,GO:BP,GO:0009967,positive regulation of signal transduction,1706,48,23,0.4791666666666667,0.013481828839390387 2.1487323418101937e-08,GO:BP,GO:0071867,response to monoamine,107,48,9,0.1875,0.08411214953271028 2.1487323418101937e-08,GO:BP,GO:0071869,response to catecholamine,107,48,9,0.1875,0.08411214953271028 2.160921983376719e-08,GO:BP,GO:1902533,positive regulation of intracellular signal transduction,1067,48,19,0.3958333333333333,0.01780693533270853 2.2552739853329426e-08,GO:BP,GO:0010647,positive regulation of cell communication,1914,48,24,0.5,0.012539184952978056 2.4117062498376673e-08,GO:BP,GO:0023056,positive regulation of signaling,1920,48,24,0.5,0.0125 3.364933322234461e-08,GO:BP,GO:0007268,chemical synaptic transmission,694,48,16,0.3333333333333333,0.023054755043227664 3.364933322234461e-08,GO:BP,GO:0098916,anterograde trans-synaptic signaling,694,48,16,0.3333333333333333,0.023054755043227664 3.994668840541558e-08,GO:BP,GO:0099537,trans-synaptic signaling,702,48,16,0.3333333333333333,0.022792022792022793 4.463786729261712e-08,GO:BP,GO:0070372,regulation of ERK1 and ERK2 cascade,306,48,12,0.25,0.0392156862745098 4.8287179966636205e-08,GO:BP,GO:0065009,regulation of molecular function,3084,48,29,0.6041666666666666,0.00940337224383917 6.333785423000241e-08,GO:BP,GO:0099536,synaptic signaling,724,48,16,0.3333333333333333,0.022099447513812154 7.396571089127725e-08,GO:BP,GO:0010959,regulation of metal ion transport,407,48,13,0.2708333333333333,0.03194103194103194 8.646867175368432e-08,GO:BP,GO:0032879,regulation of localization,2913,48,28,0.5833333333333334,0.009612083762444216 1.4399971296982144e-07,GO:BP,GO:0001934,positive regulation of protein phosphorylation,1039,48,18,0.375,0.017324350336862367 1.58314181210214e-07,GO:BP,GO:0006812,cation transport,1197,48,19,0.3958333333333333,0.015873015873015872 1.6286167511929245e-07,GO:BP,GO:0009966,regulation of signal transduction,3236,48,29,0.6041666666666666,0.00896168108776267 1.633132220672762e-07,GO:BP,GO:1903351,cellular response to dopamine,87,48,8,0.16666666666666666,0.09195402298850575 1.7928917163372186e-07,GO:BP,GO:1903350,response to dopamine,88,48,8,0.16666666666666666,0.09090909090909091 1.8284579776163347e-07,GO:BP,GO:0030001,metal ion transport,911,48,17,0.3541666666666667,0.018660812294182216 2.642102576909804e-07,GO:BP,GO:0048583,regulation of response to stimulus,4399,48,33,0.6875,0.0075017049329393045 3.511235039094195e-07,GO:BP,GO:0000165,MAPK cascade,950,48,17,0.3541666666666667,0.017894736842105262 4.0645234007498667e-07,GO:BP,GO:0023014,signal transduction by protein phosphorylation,959,48,17,0.3541666666666667,0.017726798748696558 4.5014642281378477e-07,GO:BP,GO:0042327,positive regulation of phosphorylation,1114,48,18,0.375,0.01615798922800718 5.782924140083939e-07,GO:BP,GO:0045834,positive regulation of lipid metabolic process,154,48,9,0.1875,0.05844155844155844 6.151754159250211e-07,GO:BP,GO:0044093,positive regulation of molecular function,1833,48,22,0.4583333333333333,0.012002182214948172 7.121368479156981e-07,GO:BP,GO:0050794,regulation of cellular process,11418,48,48,1.0,0.004203888596952181 7.563302692545701e-07,GO:BP,GO:0051239,regulation of multicellular organismal process,3441,48,29,0.6041666666666666,0.00842778262133101 7.590120652535923e-07,GO:BP,GO:0009214,cyclic nucleotide catabolic process,15,48,5,0.10416666666666667,0.3333333333333333 7.65491538314063e-07,GO:BP,GO:0071396,cellular response to lipid,603,48,14,0.2916666666666667,0.02321724709784411 9.437771953366571e-07,GO:BP,GO:0019233,sensory perception of pain,108,48,8,0.16666666666666666,0.07407407407407407 9.448723142734464e-07,GO:BP,GO:0031325,positive regulation of cellular metabolic process,3472,48,29,0.6041666666666666,0.008352534562211982 9.723761479290825e-07,GO:BP,GO:0019220,regulation of phosphate metabolic process,1877,48,22,0.4583333333333333,0.011720831113478956 9.824032688861946e-07,GO:BP,GO:0051174,regulation of phosphorus metabolic process,1878,48,22,0.4583333333333333,0.011714589989350373 9.977283927014359e-07,GO:BP,GO:0001932,regulation of protein phosphorylation,1506,48,20,0.4166666666666667,0.013280212483399735 1.0547576309207787e-06,GO:BP,GO:0033674,positive regulation of kinase activity,618,48,14,0.2916666666666667,0.022653721682847898 1.19619123227307e-06,GO:BP,GO:0044057,regulation of system process,624,48,14,0.2916666666666667,0.022435897435897436 1.3816343091615998e-06,GO:BP,GO:0032501,multicellular organismal process,7992,48,42,0.875,0.005255255255255256 1.4576338402841213e-06,GO:BP,GO:0046777,protein autophosphorylation,240,48,10,0.20833333333333334,0.041666666666666664 1.578327116096268e-06,GO:BP,GO:0051173,positive regulation of nitrogen compound metabolic process,3285,48,28,0.5833333333333334,0.00852359208523592 1.6653066189615112e-06,GO:BP,GO:0042493,response to drug,419,48,12,0.25,0.028639618138424822 1.781003533674441e-06,GO:BP,GO:0051247,positive regulation of protein metabolic process,1742,48,21,0.4375,0.012055109070034443 1.919328694007498e-06,GO:BP,GO:0048518,positive regulation of biological process,6416,48,38,0.7916666666666666,0.0059226932668329174 2.0501620570383983e-06,GO:BP,GO:0010517,regulation of phospholipase activity,73,48,7,0.14583333333333334,0.0958904109589041 2.5486332515112895e-06,GO:BP,GO:0019216,regulation of lipid metabolic process,435,48,12,0.25,0.027586206896551724 2.8041353563560515e-06,GO:BP,GO:0042060,wound healing,547,48,13,0.2708333333333333,0.02376599634369287 3.382512408131569e-06,GO:BP,GO:0048522,positive regulation of cellular process,5803,48,36,0.75,0.006203687747716698 3.4124410559865597e-06,GO:BP,GO:0007187,"G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger",262,48,10,0.20833333333333334,0.03816793893129771 3.50328247444143e-06,GO:BP,GO:0031401,positive regulation of protein modification process,1265,48,18,0.375,0.014229249011857707 3.7815467658034567e-06,GO:BP,GO:0006796,phosphate-containing compound metabolic process,3408,48,28,0.5833333333333334,0.008215962441314555 3.973255283807237e-06,GO:BP,GO:0009628,response to abiotic stimulus,1275,48,18,0.375,0.01411764705882353 4.353738802446278e-06,GO:BP,GO:0009893,positive regulation of metabolic process,3970,48,30,0.625,0.007556675062972292 4.526169782670645e-06,GO:BP,GO:0006793,phosphorus metabolic process,3434,48,28,0.5833333333333334,0.008153756552125802 4.794724930380598e-06,GO:BP,GO:0019932,second-messenger-mediated signaling,460,48,12,0.25,0.02608695652173913 4.960487214330714e-06,GO:BP,GO:0006468,protein phosphorylation,2044,48,22,0.4583333333333333,0.010763209393346379 5.079240566153159e-06,GO:BP,GO:0032270,positive regulation of cellular protein metabolic process,1652,48,20,0.4166666666666667,0.012106537530266344 5.2923169844107025e-06,GO:BP,GO:0051347,positive regulation of transferase activity,700,48,14,0.2916666666666667,0.02 6.082578175829916e-06,GO:BP,GO:0062197,cellular response to chemical stress,368,48,11,0.22916666666666666,0.029891304347826088 6.463651605748063e-06,GO:BP,GO:0042325,regulation of phosphorylation,1675,48,20,0.4166666666666667,0.011940298507462687 7.315894370456867e-06,GO:BP,GO:0009605,response to external stimulus,2995,48,26,0.5416666666666666,0.008681135225375626 8.262496632898256e-06,GO:BP,GO:0098660,inorganic ion transmembrane transport,862,48,15,0.3125,0.01740139211136891 8.737818284030688e-06,GO:BP,GO:0018108,peptidyl-tyrosine phosphorylation,381,48,11,0.22916666666666666,0.028871391076115485 8.956799867769533e-06,GO:BP,GO:1903727,positive regulation of phospholipid metabolic process,50,48,6,0.125,0.12 9.058694212861462e-06,GO:BP,GO:0050789,regulation of biological process,12038,48,48,1.0,0.003987373317826882 9.392568652107715e-06,GO:BP,GO:0071222,cellular response to lipopolysaccharide,211,48,9,0.1875,0.04265402843601896 9.481561305686233e-06,GO:BP,GO:0018212,peptidyl-tyrosine modification,384,48,11,0.22916666666666666,0.028645833333333332 1.4909112326066579e-05,GO:BP,GO:0070848,response to growth factor,759,48,14,0.2916666666666667,0.01844532279314888 1.584185667322761e-05,GO:BP,GO:0071219,cellular response to molecule of bacterial origin,224,48,9,0.1875,0.04017857142857143 1.7954102037304714e-05,GO:BP,GO:0019637,organophosphate metabolic process,1066,48,16,0.3333333333333333,0.0150093808630394 1.9124149587775864e-05,GO:BP,GO:0009617,response to bacterium,774,48,14,0.2916666666666667,0.01808785529715762 1.9267237639931784e-05,GO:BP,GO:0048878,chemical homeostasis,1235,48,17,0.3541666666666667,0.013765182186234818 1.9934396360934124e-05,GO:BP,GO:0043549,regulation of kinase activity,920,48,15,0.3125,0.016304347826086956 2.046506610824106e-05,GO:BP,GO:0060191,regulation of lipase activity,101,48,7,0.14583333333333334,0.06930693069306931 2.108858886765273e-05,GO:BP,GO:0010604,positive regulation of macromolecule metabolic process,3667,48,28,0.5833333333333334,0.00763566948459231 2.1907740801657893e-05,GO:BP,GO:0006198,cAMP catabolic process,10,48,4,0.08333333333333333,0.4 2.407609008302903e-05,GO:BP,GO:0009725,response to hormone,933,48,15,0.3125,0.01607717041800643 3.317898946280194e-05,GO:BP,GO:0009611,response to wounding,672,48,13,0.2708333333333333,0.019345238095238096 3.7014550865898864e-05,GO:BP,GO:0006816,calcium ion transport,438,48,11,0.22916666666666666,0.02511415525114155 3.968389792598826e-05,GO:BP,GO:0043085,positive regulation of catalytic activity,1475,48,18,0.375,0.012203389830508475 3.9739398572371864e-05,GO:BP,GO:0071216,cellular response to biotic stimulus,249,48,9,0.1875,0.03614457831325301 4.56212104385032e-05,GO:BP,GO:0048608,reproductive structure development,447,48,11,0.22916666666666666,0.024608501118568233 4.7760742913714145e-05,GO:BP,GO:0042391,regulation of membrane potential,449,48,11,0.22916666666666666,0.024498886414253896 4.920408191959205e-05,GO:BP,GO:0009154,purine ribonucleotide catabolic process,32,48,5,0.10416666666666667,0.15625 4.998944019117207e-05,GO:BP,GO:0061458,reproductive system development,451,48,11,0.22916666666666666,0.024390243902439025 5.143678023373698e-05,GO:BP,GO:0050801,ion homeostasis,837,48,14,0.2916666666666667,0.016726403823178016 5.360090523774096e-05,GO:BP,GO:0051240,positive regulation of multicellular organismal process,1894,48,20,0.4166666666666667,0.010559662090813094 5.7875188472121106e-05,GO:BP,GO:0009261,ribonucleotide catabolic process,33,48,5,0.10416666666666667,0.15151515151515152 6.560999251332585e-05,GO:BP,GO:1904062,regulation of cation transmembrane transport,357,48,10,0.20833333333333334,0.028011204481792718 7.186974303975146e-05,GO:BP,GO:0031399,regulation of protein modification process,1927,48,20,0.4166666666666667,0.010378827192527244 7.454986109349251e-05,GO:BP,GO:0034220,ion transmembrane transport,1179,48,16,0.3333333333333333,0.013570822731128074 7.627225997403139e-05,GO:BP,GO:0006979,response to oxidative stress,470,48,11,0.22916666666666666,0.023404255319148935 7.878900201388143e-05,GO:BP,GO:0006936,muscle contraction,364,48,10,0.20833333333333334,0.027472527472527472 7.900750421525136e-05,GO:BP,GO:0007186,G protein-coupled receptor signaling pathway,1358,48,17,0.3541666666666667,0.012518409425625921 8.118113309157733e-05,GO:BP,GO:0048609,multicellular organismal reproductive process,868,48,14,0.2916666666666667,0.016129032258064516 8.427060614591175e-05,GO:BP,GO:0042698,ovulation cycle,72,48,6,0.125,0.08333333333333333 8.497630693424677e-05,GO:BP,GO:0003012,muscle system process,475,48,11,0.22916666666666666,0.023157894736842106 8.897399647762038e-05,GO:BP,GO:0051338,regulation of transferase activity,1029,48,15,0.3125,0.014577259475218658 8.962917185557752e-05,GO:BP,GO:0071363,cellular response to growth factor stimulus,731,48,13,0.2708333333333333,0.017783857729138167 0.00010075490674882246,GO:BP,GO:0070838,divalent metal ion transport,483,48,11,0.22916666666666666,0.022774327122153208 0.0001064081777171789,GO:BP,GO:0032504,multicellular organism reproduction,887,48,14,0.2916666666666667,0.015783540022547914 0.00011665071947407648,GO:BP,GO:0072511,divalent inorganic cation transport,490,48,11,0.22916666666666666,0.022448979591836733 0.0001173676310195502,GO:BP,GO:0098655,cation transmembrane transport,894,48,14,0.2916666666666667,0.015659955257270694 0.00011755162563879602,GO:BP,GO:0065007,biological regulation,12697,48,48,1.0,0.0037804205717886113 0.00013528465349943453,GO:BP,GO:0051246,regulation of protein metabolic process,2917,48,24,0.5,0.0082276311278711 0.000136884238413077,GO:BP,GO:0035924,cellular response to vascular endothelial growth factor stimulus,78,48,6,0.125,0.07692307692307693 0.00013752396633683641,GO:BP,GO:0034765,regulation of ion transmembrane transport,498,48,11,0.22916666666666666,0.02208835341365462 0.00014580014411020957,GO:BP,GO:0007169,transmembrane receptor protein tyrosine kinase signaling pathway,762,48,13,0.2708333333333333,0.01706036745406824 0.00016721899849042327,GO:BP,GO:0098662,inorganic cation transmembrane transport,771,48,13,0.2708333333333333,0.016861219195849545 0.0001798558908400357,GO:BP,GO:0009187,cyclic nucleotide metabolic process,41,48,5,0.10416666666666667,0.12195121951219512 0.00018174082137317085,GO:BP,GO:0044419,interspecies interaction between organisms,2254,48,21,0.4375,0.009316770186335404 0.00019169960803361392,GO:BP,GO:0043066,negative regulation of apoptotic process,930,48,14,0.2916666666666667,0.015053763440860216 0.00019242080305707066,GO:BP,GO:0050877,nervous system process,1443,48,17,0.3541666666666667,0.01178101178101178 0.00021050274606784368,GO:BP,GO:0016310,phosphorylation,2501,48,22,0.4583333333333333,0.008796481407437025 0.00025021665213643875,GO:BP,GO:0032268,regulation of cellular protein metabolic process,2763,48,23,0.4791666666666667,0.008324285197249367 0.000259323552382336,GO:BP,GO:0043069,negative regulation of programmed cell death,953,48,14,0.2916666666666667,0.014690451206715634 0.00029089721981948193,GO:BP,GO:0006195,purine nucleotide catabolic process,45,48,5,0.10416666666666667,0.1111111111111111 0.00029506074918296137,GO:BP,GO:0019935,cyclic-nucleotide-mediated signaling,224,48,8,0.16666666666666666,0.03571428571428571 0.000302945599271056,GO:BP,GO:0051899,membrane depolarization,89,48,6,0.125,0.06741573033707865 0.00031260912991481327,GO:BP,GO:0051094,positive regulation of developmental process,1492,48,17,0.3541666666666667,0.011394101876675604 0.0003970541295567872,GO:BP,GO:0014065,phosphatidylinositol 3-kinase signaling,155,48,7,0.14583333333333334,0.04516129032258064 0.0004000865770328829,GO:BP,GO:0050793,regulation of developmental process,2833,48,23,0.4791666666666667,0.008118602188492764 0.0004034456249825484,GO:BP,GO:0048589,developmental growth,687,48,12,0.25,0.017467248908296942 0.00047147663513104256,GO:BP,GO:1903530,regulation of secretion by cell,697,48,12,0.25,0.01721664275466284 0.0004765684948517669,GO:BP,GO:1903725,regulation of phospholipid metabolic process,96,48,6,0.125,0.0625 0.0005470557491121382,GO:BP,GO:0050790,regulation of catalytic activity,2402,48,21,0.4375,0.008742714404662781 0.0006102422559484492,GO:BP,GO:0038084,vascular endothelial growth factor signaling pathway,52,48,5,0.10416666666666667,0.09615384615384616 0.0006234757292824324,GO:BP,GO:0033002,muscle cell proliferation,247,48,8,0.16666666666666666,0.032388663967611336 0.0006382094774771524,GO:BP,GO:0010035,response to inorganic substance,580,48,11,0.22916666666666666,0.01896551724137931 0.0006724693103439707,GO:BP,GO:0072523,purine-containing compound catabolic process,53,48,5,0.10416666666666667,0.09433962264150944 0.0007396150135605768,GO:BP,GO:0009712,catechol-containing compound metabolic process,54,48,5,0.10416666666666667,0.09259259259259259 0.0007396150135605768,GO:BP,GO:0043949,regulation of cAMP-mediated signaling,54,48,5,0.10416666666666667,0.09259259259259259 0.0007396150135605768,GO:BP,GO:0006584,catecholamine metabolic process,54,48,5,0.10416666666666667,0.09259259259259259 0.0007441029783882614,GO:BP,GO:0034762,regulation of transmembrane transport,589,48,11,0.22916666666666666,0.01867572156196944 0.000764168734062177,GO:BP,GO:0072359,circulatory system development,1213,48,15,0.3125,0.01236603462489695 0.0008210118345918387,GO:BP,GO:0060548,negative regulation of cell death,1047,48,14,0.2916666666666667,0.013371537726838587 0.0008437175668255511,GO:BP,GO:0006915,apoptotic process,2013,48,19,0.3958333333333333,0.009438648782911079 0.000900591898529143,GO:BP,GO:0046058,cAMP metabolic process,23,48,4,0.08333333333333333,0.17391304347826086 0.001103985688306399,GO:BP,GO:0007166,cell surface receptor signaling pathway,3250,48,24,0.5,0.0073846153846153844 0.0011059135361991082,GO:BP,GO:0032502,developmental process,6676,48,35,0.7291666666666666,0.005242660275614141 0.0011258372184503652,GO:BP,GO:0051046,regulation of secretion,756,48,12,0.25,0.015873015873015872 0.0011323287656896958,GO:BP,GO:0055085,transmembrane transport,1632,48,17,0.3541666666666667,0.010416666666666666 0.0011427893948361496,GO:BP,GO:0007610,behavior,615,48,11,0.22916666666666666,0.01788617886178862 0.0011591109271238422,GO:BP,GO:0032412,regulation of ion transmembrane transporter activity,268,48,8,0.16666666666666666,0.029850746268656716 0.0011992006252734457,GO:BP,GO:0023061,signal release,618,48,11,0.22916666666666666,0.01779935275080906 0.0012297336177136008,GO:BP,GO:0030154,cell differentiation,4388,48,28,0.5833333333333334,0.006381039197812215 0.0012852633505436482,GO:BP,GO:0006629,lipid metabolic process,1450,48,16,0.3333333333333333,0.011034482758620689 0.0013582409461864375,GO:BP,GO:0008219,cell death,2300,48,20,0.4166666666666667,0.008695652173913044 0.0014820555538906262,GO:BP,GO:0009891,positive regulation of biosynthetic process,2087,48,19,0.3958333333333333,0.009103977000479156 0.0014894648019866826,GO:BP,GO:0010518,positive regulation of phospholipase activity,62,48,5,0.10416666666666667,0.08064516129032258 0.0015115898843426452,GO:BP,GO:0043951,negative regulation of cAMP-mediated signaling,26,48,4,0.08333333333333333,0.15384615384615385 0.0015290812437111282,GO:BP,GO:0043491,protein kinase B signaling,278,48,8,0.16666666666666666,0.02877697841726619 0.001571092129824059,GO:BP,GO:0022898,regulation of transmembrane transporter activity,279,48,8,0.16666666666666666,0.02867383512544803 0.0016363698931840876,GO:BP,GO:0048015,phosphatidylinositol-mediated signaling,191,48,7,0.14583333333333334,0.03664921465968586 0.0016646169534393724,GO:BP,GO:0048519,negative regulation of biological process,5719,48,32,0.6666666666666666,0.005595383808358104 0.0018172294711479586,GO:BP,GO:0008217,regulation of blood pressure,194,48,7,0.14583333333333334,0.03608247422680412 0.0018275324094961343,GO:BP,GO:0048869,cellular developmental process,4468,48,28,0.5833333333333334,0.006266786034019696 0.0018300447209482562,GO:BP,GO:0048523,negative regulation of cellular process,5086,48,30,0.625,0.005898545025560362 0.0018811262421891454,GO:BP,GO:0048017,inositol lipid-mediated signaling,195,48,7,0.14583333333333334,0.035897435897435895 0.0020842547788802496,GO:BP,GO:0019933,cAMP-mediated signaling,198,48,7,0.14583333333333334,0.03535353535353535 0.0020952634957007435,GO:BP,GO:0051050,positive regulation of transport,961,48,13,0.2708333333333333,0.013527575442247659 0.0021041498835408703,GO:BP,GO:0018193,peptidyl-amino acid modification,1313,48,15,0.3125,0.011424219345011425 0.0021077131219963334,GO:BP,GO:0009888,tissue development,2135,48,19,0.3958333333333333,0.008899297423887589 0.002200941301247364,GO:BP,GO:0060135,maternal process involved in female pregnancy,67,48,5,0.10416666666666667,0.07462686567164178 0.002200941301247364,GO:BP,GO:0009166,nucleotide catabolic process,67,48,5,0.10416666666666667,0.07462686567164178 0.0023305069539367785,GO:BP,GO:0032409,regulation of transporter activity,294,48,8,0.16666666666666666,0.027210884353741496 0.0023601848240342987,GO:BP,GO:0048856,anatomical structure development,6143,48,33,0.6875,0.005371968093765262 0.002398382240886386,GO:BP,GO:0022414,reproductive process,1519,48,16,0.3333333333333333,0.01053324555628703 0.002462382266356424,GO:BP,GO:0000003,reproduction,1522,48,16,0.3333333333333333,0.010512483574244415 0.0024863647526430104,GO:BP,GO:0012501,programmed cell death,2158,48,19,0.3958333333333333,0.008804448563484708 0.0028074708501573805,GO:BP,GO:0060541,respiratory system development,207,48,7,0.14583333333333334,0.033816425120772944 0.0028638904071371903,GO:BP,GO:1903409,reactive oxygen species biosynthetic process,130,48,6,0.125,0.046153846153846156 0.0028638904071371903,GO:BP,GO:0014066,regulation of phosphatidylinositol 3-kinase signaling,130,48,6,0.125,0.046153846153846156 0.0029081312972846153,GO:BP,GO:0009117,nucleotide metabolic process,538,48,10,0.20833333333333334,0.01858736059479554 0.003131713488290063,GO:BP,GO:0010595,positive regulation of endothelial cell migration,132,48,6,0.125,0.045454545454545456 0.0031457337929792686,GO:BP,GO:1903522,regulation of blood circulation,306,48,8,0.16666666666666666,0.026143790849673203 0.003322498152548484,GO:BP,GO:0006753,nucleoside phosphate metabolic process,546,48,10,0.20833333333333334,0.018315018315018316 0.0033501848455147185,GO:BP,GO:0003006,developmental process involved in reproduction,1002,48,13,0.2708333333333333,0.012974051896207584 0.0033824474357072383,GO:BP,GO:1901292,nucleoside phosphate catabolic process,73,48,5,0.10416666666666667,0.0684931506849315 0.0034132846737468655,GO:BP,GO:0010941,regulation of cell death,1765,48,17,0.3541666666666667,0.009631728045325779 0.003425775849650766,GO:BP,GO:0040007,growth,1004,48,13,0.2708333333333333,0.012948207171314742 0.0035048322545633026,GO:BP,GO:1901564,organonitrogen compound metabolic process,6961,48,35,0.7291666666666666,0.005028013216491883 0.0035510856526682504,GO:BP,GO:0048511,rhythmic process,311,48,8,0.16666666666666666,0.02572347266881029 0.0035935188852659243,GO:BP,GO:0098664,G protein-coupled serotonin receptor signaling pathway,32,48,4,0.08333333333333333,0.125 0.003620340760504566,GO:BP,GO:0086003,cardiac muscle cell contraction,74,48,5,0.10416666666666667,0.06756756756756757 0.004000193368111971,GO:BP,GO:0034599,cellular response to oxidative stress,316,48,8,0.16666666666666666,0.02531645569620253 0.004081193877927135,GO:BP,GO:0043552,positive regulation of phosphatidylinositol 3-kinase activity,33,48,4,0.08333333333333333,0.12121212121212122 0.004135609044892233,GO:BP,GO:0060193,positive regulation of lipase activity,76,48,5,0.10416666666666667,0.06578947368421052 0.004393539992683557,GO:BP,GO:0070588,calcium ion transmembrane transport,320,48,8,0.16666666666666666,0.025 0.004740069437784654,GO:BP,GO:0006810,transport,5299,48,30,0.625,0.005661445555765239 0.004779011597797794,GO:BP,GO:0051707,response to other organism,1600,48,16,0.3333333333333333,0.01 0.004796722323746,GO:BP,GO:0030534,adult behavior,142,48,6,0.125,0.04225352112676056 0.004819398174809361,GO:BP,GO:0007204,positive regulation of cytosolic calcium ion concentration,324,48,8,0.16666666666666666,0.024691358024691357 0.0048583957666752066,GO:BP,GO:0043207,response to external biotic stimulus,1602,48,16,0.3333333333333333,0.009987515605493134 0.004858795665937664,GO:BP,GO:0044281,small molecule metabolic process,2028,48,18,0.375,0.008875739644970414 0.004996782997516646,GO:BP,GO:0060048,cardiac muscle contraction,143,48,6,0.125,0.04195804195804196 0.005015014982075357,GO:BP,GO:0043536,positive regulation of blood vessel endothelial cell migration,79,48,5,0.10416666666666667,0.06329113924050633 0.005103768204121946,GO:BP,GO:0042981,regulation of apoptotic process,1608,48,16,0.3333333333333333,0.009950248756218905 0.005203605114922628,GO:BP,GO:0097553,calcium ion transmembrane import into cytosol,144,48,6,0.125,0.041666666666666664 0.005203605114922628,GO:BP,GO:0032355,response to estradiol,144,48,6,0.125,0.041666666666666664 0.005203605114922628,GO:BP,GO:0045471,response to ethanol,144,48,6,0.125,0.041666666666666664 0.005724419504654137,GO:BP,GO:0044283,small molecule biosynthetic process,725,48,11,0.22916666666666666,0.015172413793103448 0.005763429800464653,GO:BP,GO:0031328,positive regulation of cellular biosynthetic process,2052,48,18,0.375,0.008771929824561403 0.005840607317276635,GO:BP,GO:0086010,membrane depolarization during action potential,36,48,4,0.08333333333333333,0.1111111111111111 0.00630204393324815,GO:BP,GO:0043067,regulation of programmed cell death,1634,48,16,0.3333333333333333,0.009791921664626682 0.00630204393324815,GO:BP,GO:0009607,response to biotic stimulus,1634,48,16,0.3333333333333333,0.009791921664626682 0.006345360706785965,GO:BP,GO:0097746,regulation of blood vessel diameter,149,48,6,0.125,0.040268456375838924 0.006345360706785965,GO:BP,GO:0035296,regulation of tube diameter,149,48,6,0.125,0.040268456375838924 0.006349788716648193,GO:BP,GO:0007188,adenylate cyclase-modulating G protein-coupled receptor signaling pathway,234,48,7,0.14583333333333334,0.029914529914529916 0.006535777674789032,GO:BP,GO:0090218,positive regulation of lipid kinase activity,37,48,4,0.08333333333333333,0.10810810810810811 0.006535777674789032,GO:BP,GO:0007210,serotonin receptor signaling pathway,37,48,4,0.08333333333333333,0.10810810810810811 0.0065965293591076606,GO:BP,GO:0035150,regulation of tube size,150,48,6,0.125,0.04 0.006688635050217316,GO:BP,GO:0031323,regulation of cellular metabolic process,6399,48,33,0.6875,0.005157055789967183 0.007103589436264902,GO:BP,GO:0000302,response to reactive oxygen species,238,48,7,0.14583333333333334,0.029411764705882353 0.0072123242392667505,GO:BP,GO:0015844,monoamine transport,85,48,5,0.10416666666666667,0.058823529411764705 0.0072123242392667505,GO:BP,GO:0002028,regulation of sodium ion transport,85,48,5,0.10416666666666667,0.058823529411764705 0.007290435292234367,GO:BP,GO:0090050,positive regulation of cell migration involved in sprouting angiogenesis,38,48,4,0.08333333333333333,0.10526315789473684 0.007290435292234367,GO:BP,GO:0001893,maternal placenta development,38,48,4,0.08333333333333333,0.10526315789473684 0.007977113116230464,GO:BP,GO:0062013,positive regulation of small molecule metabolic process,155,48,6,0.125,0.03870967741935484 0.008092186075890599,GO:BP,GO:0007193,adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway,87,48,5,0.10416666666666667,0.05747126436781609 0.0081077726715857,GO:BP,GO:0042417,dopamine metabolic process,39,48,4,0.08333333333333333,0.10256410256410256 0.008184274622215331,GO:BP,GO:0051234,establishment of localization,5427,48,30,0.625,0.00552791597567717 0.008450007238215972,GO:BP,GO:0040017,positive regulation of locomotion,606,48,10,0.20833333333333334,0.0165016501650165 0.008881846250101019,GO:BP,GO:0040012,regulation of locomotion,1094,48,13,0.2708333333333333,0.011882998171846435 0.009054260553813982,GO:BP,GO:0014068,positive regulation of phosphatidylinositol 3-kinase signaling,89,48,5,0.10416666666666667,0.056179775280898875 0.009062133883653027,GO:BP,GO:0032101,regulation of response to external stimulus,1096,48,13,0.2708333333333333,0.011861313868613138 0.009288344579220462,GO:BP,GO:0048545,response to steroid hormone,354,48,8,0.16666666666666666,0.022598870056497175 0.009622713912898593,GO:BP,GO:0007167,enzyme linked receptor protein signaling pathway,1102,48,13,0.2708333333333333,0.011796733212341199 0.009723497909662942,GO:BP,GO:0098771,inorganic ion homeostasis,766,48,11,0.22916666666666666,0.014360313315926894 0.009827915791549364,GO:BP,GO:0009636,response to toxic substance,250,48,7,0.14583333333333334,0.028 0.010669299483656108,GO:BP,GO:0060402,calcium ion transport into cytosol,163,48,6,0.125,0.03680981595092025 0.010669299483656108,GO:BP,GO:0031214,biomineral tissue development,163,48,6,0.125,0.03680981595092025 0.010729716172260503,GO:BP,GO:0051480,regulation of cytosolic calcium ion concentration,361,48,8,0.16666666666666666,0.0221606648199446 0.010800293325498712,GO:BP,GO:0001525,angiogenesis,623,48,10,0.20833333333333334,0.016051364365971106 0.010909999630127627,GO:BP,GO:0051896,regulation of protein kinase B signaling,254,48,7,0.14583333333333334,0.027559055118110236 0.011052309614840187,GO:BP,GO:0110148,biomineralization,164,48,6,0.125,0.036585365853658534 0.011591722647161223,GO:BP,GO:0055086,nucleobase-containing small molecule metabolic process,628,48,10,0.20833333333333334,0.01592356687898089 0.011730152005279501,GO:BP,GO:0080090,regulation of primary metabolic process,6191,48,32,0.6666666666666666,0.0051687934097884025 0.012361358496392862,GO:BP,GO:0051179,localization,6920,48,34,0.7083333333333334,0.004913294797687861 0.013712108631464803,GO:BP,GO:0051924,regulation of calcium ion transport,263,48,7,0.14583333333333334,0.026615969581749048 0.014058588552629158,GO:BP,GO:0034614,cellular response to reactive oxygen species,171,48,6,0.125,0.03508771929824561 0.015066722020776269,GO:BP,GO:0050966,detection of mechanical stimulus involved in sensory perception of pain,14,48,3,0.0625,0.21428571428571427 0.015535410395653631,GO:BP,GO:0048660,regulation of smooth muscle cell proliferation,174,48,6,0.125,0.034482758620689655 0.015894594413397977,GO:BP,GO:0003018,vascular process in circulatory system,269,48,7,0.14583333333333334,0.026022304832713755 0.015994720951646425,GO:BP,GO:0001568,blood vessel development,807,48,11,0.22916666666666666,0.013630731102850062 0.016120306730338915,GO:BP,GO:0045595,regulation of cell differentiation,1976,48,17,0.3541666666666667,0.00860323886639676 0.016548131112518735,GO:BP,GO:0007208,phospholipase C-activating serotonin receptor signaling pathway,2,48,2,0.041666666666666664,1.0 0.016548131112518735,GO:BP,GO:0031635,adenylate cyclase-inhibiting opioid receptor signaling pathway,2,48,2,0.041666666666666664,1.0 0.016588171209005634,GO:BP,GO:0048659,smooth muscle cell proliferation,176,48,6,0.125,0.03409090909090909 0.01713586394491164,GO:BP,GO:0010634,positive regulation of epithelial cell migration,177,48,6,0.125,0.03389830508474576 0.017704937830056906,GO:BP,GO:0007200,phospholipase C-activating G protein-coupled receptor signaling pathway,102,48,5,0.10416666666666667,0.049019607843137254 0.017938000441122936,GO:BP,GO:0048534,hematopoietic or lymphoid organ development,986,48,12,0.25,0.012170385395537525 0.018275327197279638,GO:BP,GO:0051897,positive regulation of protein kinase B signaling,179,48,6,0.125,0.0335195530726257 0.018275327197279638,GO:BP,GO:0006941,striated muscle contraction,179,48,6,0.125,0.0335195530726257 0.018675257202920497,GO:BP,GO:0035295,tube development,1171,48,13,0.2708333333333333,0.011101622544833475 0.01870077712116126,GO:BP,GO:0072507,divalent inorganic cation homeostasis,519,48,9,0.1875,0.017341040462427744 0.01879814883074533,GO:BP,GO:0048148,behavioral response to cocaine,15,48,3,0.0625,0.2 0.018846203071076418,GO:BP,GO:1900274,regulation of phospholipase C activity,48,48,4,0.08333333333333333,0.08333333333333333 0.018846203071076418,GO:BP,GO:0030850,prostate gland development,48,48,4,0.08333333333333333,0.08333333333333333 0.01886769080167556,GO:BP,GO:0030324,lung development,180,48,6,0.125,0.03333333333333333 0.01893540456476743,GO:BP,GO:0050865,regulation of cell activation,664,48,10,0.20833333333333334,0.015060240963855422 0.020172142776976192,GO:BP,GO:0046883,regulation of hormone secretion,279,48,7,0.14583333333333334,0.025089605734767026 0.02048138354269631,GO:BP,GO:0045776,negative regulation of blood pressure,49,48,4,0.08333333333333333,0.08163265306122448 0.020738951824258348,GO:BP,GO:0060401,cytosolic calcium ion transport,183,48,6,0.125,0.03278688524590164 0.021220408288880017,GO:BP,GO:0051171,regulation of nitrogen compound metabolic process,5999,48,31,0.6458333333333334,0.00516752792132022 0.0213951308053209,GO:BP,GO:0030323,respiratory tube development,184,48,6,0.125,0.03260869565217391 0.021696991124793636,GO:BP,GO:0040011,locomotion,2020,48,17,0.3541666666666667,0.008415841584158416 0.02199539207445868,GO:BP,GO:0019725,cellular homeostasis,1006,48,12,0.25,0.011928429423459244 0.0221313943669493,GO:BP,GO:0071900,regulation of protein serine/threonine kinase activity,530,48,9,0.1875,0.016981132075471698 0.023413384789191242,GO:BP,GO:0034404,nucleobase-containing small molecule biosynthetic process,108,48,5,0.10416666666666667,0.046296296296296294 0.023465405705997713,GO:BP,GO:2001257,regulation of cation channel activity,187,48,6,0.125,0.03208556149732621 0.02406287929543602,GO:BP,GO:0042220,response to cocaine,51,48,4,0.08333333333333333,0.0784313725490196 0.02422043372302663,GO:BP,GO:0010817,regulation of hormone levels,536,48,9,0.1875,0.016791044776119403 0.024447472427428077,GO:BP,GO:0001944,vasculature development,844,48,11,0.22916666666666666,0.013033175355450236 0.024801638074576922,GO:BP,GO:0072593,reactive oxygen species metabolic process,288,48,7,0.14583333333333334,0.024305555555555556 0.02560548624535233,GO:BP,GO:0018958,phenol-containing compound metabolic process,110,48,5,0.10416666666666667,0.045454545454545456 0.02560548624535233,GO:BP,GO:0043266,regulation of potassium ion transport,110,48,5,0.10416666666666667,0.045454545454545456 0.026528095954507315,GO:BP,GO:0043270,positive regulation of ion transport,291,48,7,0.14583333333333334,0.024054982817869417 0.027267161817524036,GO:BP,GO:0015672,monovalent inorganic cation transport,544,48,9,0.1875,0.016544117647058824 0.027733591455098353,GO:BP,GO:0060047,heart contraction,293,48,7,0.14583333333333334,0.023890784982935155 0.027954820667188403,GO:BP,GO:0043279,response to alkaloid,112,48,5,0.10416666666666667,0.044642857142857144 0.028086228687234108,GO:BP,GO:0003044,regulation of systemic arterial blood pressure mediated by a chemical signal,53,48,4,0.08333333333333333,0.07547169811320754 0.028093670837154736,GO:BP,GO:0035265,organ growth,193,48,6,0.125,0.031088082901554404 0.029469102081978477,GO:BP,GO:0006928,movement of cell or subcellular component,2301,48,18,0.375,0.007822685788787484 0.030012125476945935,GO:BP,GO:0048731,system development,5096,48,28,0.5833333333333334,0.005494505494505495 0.030646016854113712,GO:BP,GO:0048646,anatomical structure formation involved in morphogenesis,1226,48,13,0.2708333333333333,0.010603588907014683 0.030769047814345477,GO:BP,GO:0002520,immune system development,1040,48,12,0.25,0.011538461538461539 0.03315695968987263,GO:BP,GO:0030282,bone mineralization,116,48,5,0.10416666666666667,0.04310344827586207 0.033523791451507065,GO:BP,GO:0044849,estrous cycle,18,48,3,0.0625,0.16666666666666666 0.034464759141614974,GO:BP,GO:0003015,heart process,303,48,7,0.14583333333333334,0.0231023102310231 0.03502277303179984,GO:BP,GO:0086002,cardiac muscle cell action potential involved in contraction,56,48,4,0.08333333333333333,0.07142857142857142 0.036398028423772474,GO:BP,GO:0002040,sprouting angiogenesis,202,48,6,0.125,0.0297029702970297 0.03741242742276416,GO:BP,GO:0090087,regulation of peptide transport,718,48,10,0.20833333333333334,0.013927576601671309 0.03786560728615995,GO:BP,GO:0048514,blood vessel morphogenesis,719,48,10,0.20833333333333334,0.013908205841446454 0.03899589944063743,GO:BP,GO:0030335,positive regulation of cell migration,569,48,9,0.1875,0.015817223198594025 0.03956983752284644,GO:BP,GO:0007565,female pregnancy,205,48,6,0.125,0.02926829268292683 0.04029841920239634,GO:BP,GO:0043551,regulation of phosphatidylinositol 3-kinase activity,58,48,4,0.08333333333333333,0.06896551724137931 0.04067539373788675,GO:BP,GO:0035637,multicellular organismal signaling,206,48,6,0.125,0.02912621359223301 0.043144904423999764,GO:BP,GO:0046456,icosanoid biosynthetic process,59,48,4,0.08333333333333333,0.06779661016949153 0.043379480256220695,GO:BP,GO:0060326,cell chemotaxis,314,48,7,0.14583333333333334,0.022292993630573247 0.044050402608297866,GO:BP,GO:0070252,actin-mediated cell contraction,123,48,5,0.10416666666666667,0.04065040650406504 0.044540424558596366,GO:BP,GO:0002791,regulation of peptide secretion,439,48,8,0.16666666666666666,0.018223234624145785 0.04581006520936068,GO:BP,GO:0051209,release of sequestered calcium ion into cytosol,124,48,5,0.10416666666666667,0.04032258064516129 0.04613653195105559,GO:BP,GO:0006636,unsaturated fatty acid biosynthetic process,60,48,4,0.08333333333333333,0.06666666666666667 0.047624013495092654,GO:BP,GO:0051283,negative regulation of sequestering of calcium ion,125,48,5,0.10416666666666667,0.04 0.04831515600968367,GO:BP,GO:0006163,purine nucleotide metabolic process,444,48,8,0.16666666666666666,0.018018018018018018 0.049559884424852776,GO:BP,GO:0072275,metanephric glomerulus morphogenesis,3,48,2,0.041666666666666664,0.6666666666666666 0.049559884424852776,GO:BP,GO:0038086,VEGF-activated platelet-derived growth factor receptor signaling pathway,3,48,2,0.041666666666666664,0.6666666666666666 0.049559884424852776,GO:BP,GO:0072276,metanephric glomerulus vasculature morphogenesis,3,48,2,0.041666666666666664,0.6666666666666666 0.049559884424852776,GO:BP,GO:0038091,positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway,3,48,2,0.041666666666666664,0.6666666666666666 0.049559884424852776,GO:BP,GO:0072277,metanephric glomerular capillary formation,3,48,2,0.041666666666666664,0.6666666666666666 2.1628319837921141e-10,GO:CC,GO:0005887,integral component of plasma membrane,1615,48,23,0.4791666666666667,0.014241486068111455 5.720555544331108e-10,GO:CC,GO:0031226,intrinsic component of plasma membrane,1692,48,23,0.4791666666666667,0.013593380614657211 5.5711090245498e-08,GO:CC,GO:0043235,receptor complex,500,48,13,0.2708333333333333,0.026 6.724093254310545e-08,GO:CC,GO:0042995,cell projection,2353,48,24,0.5,0.010199745006374841 2.0190353629202066e-07,GO:CC,GO:0120025,plasma membrane bounded cell projection,2256,48,23,0.4791666666666667,0.010195035460992909 2.369141755371915e-07,GO:CC,GO:0030054,cell junction,2058,48,22,0.4583333333333333,0.010689990281827016 1.3966552146363643e-06,GO:CC,GO:0005886,plasma membrane,5655,48,34,0.7083333333333334,0.00601237842617153 2.4469853372011306e-06,GO:CC,GO:0071944,cell periphery,5768,48,34,0.7083333333333334,0.005894590846047157 5.090009804314023e-06,GO:CC,GO:0036477,somatodendritic compartment,873,48,14,0.2916666666666667,0.016036655211912942 6.008289280027645e-06,GO:CC,GO:0098590,plasma membrane region,1213,48,16,0.3333333333333333,0.013190436933223413 9.225334359870644e-05,GO:CC,GO:0030425,dendrite,627,48,11,0.22916666666666666,0.017543859649122806 9.52200156712702e-05,GO:CC,GO:0097447,dendritic tree,629,48,11,0.22916666666666666,0.017488076311605722 0.0002043865500810229,GO:CC,GO:0034702,ion channel complex,300,48,8,0.16666666666666666,0.02666666666666667 0.00025050688301671005,GO:CC,GO:0016020,membrane,9802,48,41,0.8541666666666666,0.0041828198326872065 0.0002649015853305402,GO:CC,GO:0043005,neuron projection,1396,48,15,0.3125,0.010744985673352435 0.00034759671358676686,GO:CC,GO:1902495,transmembrane transporter complex,322,48,8,0.16666666666666666,0.024844720496894408 0.00039901744555141834,GO:CC,GO:0045121,membrane raft,328,48,8,0.16666666666666666,0.024390243902439025 0.0004081888697914537,GO:CC,GO:0098857,membrane microdomain,329,48,8,0.16666666666666666,0.0243161094224924 0.0004175395497656201,GO:CC,GO:1990351,transporter complex,330,48,8,0.16666666666666666,0.024242424242424242 0.0005448122352148103,GO:CC,GO:0098589,membrane region,342,48,8,0.16666666666666666,0.023391812865497075 0.0006165619576781606,GO:CC,GO:0045202,synapse,1293,48,14,0.2916666666666667,0.01082753286929621 0.0007648268335373154,GO:CC,GO:0097060,synaptic membrane,358,48,8,0.16666666666666666,0.0223463687150838 0.001748594770528616,GO:CC,GO:0043025,neuronal cell body,535,48,9,0.1875,0.016822429906542057 0.0026456956865378058,GO:CC,GO:0001518,voltage-gated sodium channel complex,17,48,3,0.0625,0.17647058823529413 0.003274420139200406,GO:CC,GO:0016021,integral component of membrane,5699,48,29,0.6041666666666666,0.005088612037199508 0.0049219370208750685,GO:CC,GO:0044297,cell body,609,48,9,0.1875,0.014778325123152709 0.005541727135468756,GO:CC,GO:0034703,cation channel complex,225,48,6,0.125,0.02666666666666667 0.005749519613787165,GO:CC,GO:0031224,intrinsic component of membrane,5852,48,29,0.6041666666666666,0.004955570745044429 0.008822157887420077,GO:CC,GO:0034706,sodium channel complex,25,48,3,0.0625,0.12 0.01305998283066955,GO:CC,GO:0043204,perikaryon,159,48,5,0.10416666666666667,0.031446540880503145 0.013141987358706895,GO:CC,GO:0031410,cytoplasmic vesicle,2419,48,17,0.3541666666666667,0.007027697395618024 0.013424539753805094,GO:CC,GO:0097708,intracellular vesicle,2423,48,17,0.3541666666666667,0.0070160957490713995 0.014332119584427936,GO:CC,GO:0005901,caveola,82,48,4,0.08333333333333333,0.04878048780487805 0.017069519337163355,GO:CC,GO:0098805,whole membrane,1731,48,14,0.2916666666666667,0.008087810514153668 0.02432373128850563,GO:CC,GO:0031252,cell leading edge,427,48,7,0.14583333333333334,0.01639344262295082 0.03280898934952824,GO:CC,GO:0031982,vesicle,4036,48,22,0.4583333333333333,0.005450941526263627 0.04584559227748925,GO:CC,GO:0032590,dendrite membrane,43,48,3,0.0625,0.06976744186046512 0.049815109157781375,GO:CC,GO:0044853,plasma membrane raft,113,48,4,0.08333333333333333,0.035398230088495575 9.136707140918341e-11,GO:MF,GO:0060089,molecular transducer activity,1476,48,23,0.4791666666666667,0.015582655826558265 9.136707140918341e-11,GO:MF,GO:0038023,signaling receptor activity,1476,48,23,0.4791666666666667,0.015582655826558265 1.419301463167175e-09,GO:MF,GO:0004713,protein tyrosine kinase activity,144,48,10,0.20833333333333334,0.06944444444444445 1.833900015062311e-09,GO:MF,GO:0004714,transmembrane receptor protein tyrosine kinase activity,63,48,8,0.16666666666666666,0.12698412698412698 1.79746882583536e-08,GO:MF,GO:0019199,transmembrane receptor protein kinase activity,83,48,8,0.16666666666666666,0.0963855421686747 3.002644743398758e-08,GO:MF,GO:0004114,"3',5'-cyclic-nucleotide phosphodiesterase activity",27,48,6,0.125,0.2222222222222222 4.730887903867433e-08,GO:MF,GO:0004888,transmembrane signaling receptor activity,1262,48,19,0.3958333333333333,0.015055467511885896 4.7998327023966095e-08,GO:MF,GO:0004112,cyclic-nucleotide phosphodiesterase activity,29,48,6,0.125,0.20689655172413793 6.721395566946191e-07,GO:MF,GO:0005021,vascular endothelial growth factor-activated receptor activity,7,48,4,0.08333333333333333,0.5714285714285714 1.0268559759979777e-06,GO:MF,GO:0019838,growth factor binding,137,48,8,0.16666666666666666,0.058394160583941604 5.837845660298985e-06,GO:MF,GO:0030594,neurotransmitter receptor activity,109,48,7,0.14583333333333334,0.06422018348623854 9.416370262254307e-06,GO:MF,GO:0004115,"3',5'-cyclic-AMP phosphodiesterase activity",12,48,4,0.08333333333333333,0.3333333333333333 6.803481019515078e-05,GO:MF,GO:0008081,phosphoric diester hydrolase activity,93,48,6,0.125,0.06451612903225806 7.953515963195002e-05,GO:MF,GO:0038085,vascular endothelial growth factor binding,5,48,3,0.0625,0.6 7.953515963195002e-05,GO:MF,GO:0005007,fibroblast growth factor-activated receptor activity,5,48,3,0.0625,0.6 8.004284983954786e-05,GO:MF,GO:0008227,G protein-coupled amine receptor activity,49,48,5,0.10416666666666667,0.10204081632653061 0.00010539438342807683,GO:MF,GO:0043167,ion binding,6335,48,34,0.7083333333333334,0.005367008681925809 0.00011810827999001613,GO:MF,GO:0008144,drug binding,102,48,6,0.125,0.058823529411764705 0.00012899852205095632,GO:MF,GO:0004672,protein kinase activity,597,48,11,0.22916666666666666,0.018425460636515914 0.00022393650814863568,GO:MF,GO:0036094,small molecule binding,2580,48,21,0.4375,0.00813953488372093 0.00029034722324712694,GO:MF,GO:0043168,anion binding,2870,48,22,0.4583333333333333,0.007665505226480836 0.0006389031006043689,GO:MF,GO:0016773,"phosphotransferase activity, alcohol group as acceptor",702,48,11,0.22916666666666666,0.01566951566951567 0.0006586471862583952,GO:MF,GO:0099589,serotonin receptor activity,32,48,4,0.08333333333333333,0.125 0.0006586471862583952,GO:MF,GO:0004993,G protein-coupled serotonin receptor activity,32,48,4,0.08333333333333333,0.125 0.0011582289746626053,GO:MF,GO:0022836,gated channel activity,341,48,8,0.16666666666666666,0.02346041055718475 0.0011848519314580717,GO:MF,GO:0005102,signaling receptor binding,1674,48,16,0.3333333333333333,0.009557945041816009 0.0011982946594733693,GO:MF,GO:0030551,cyclic nucleotide binding,37,48,4,0.08333333333333333,0.10810810810810811 0.0016078921340284319,GO:MF,GO:0032553,ribonucleotide binding,1933,48,17,0.3541666666666667,0.008794619762027936 0.0016513688971177185,GO:MF,GO:0000166,nucleotide binding,2166,48,18,0.375,0.008310249307479225 0.001654196365644838,GO:MF,GO:0042802,identical protein binding,1937,48,17,0.3541666666666667,0.008776458440887971 0.0016623784211429054,GO:MF,GO:1901265,nucleoside phosphate binding,2167,48,18,0.375,0.008306414397784956 0.0017276766170020654,GO:MF,GO:0051378,serotonin binding,12,48,3,0.0625,0.25 0.0017276766170020654,GO:MF,GO:0043176,amine binding,12,48,3,0.0625,0.25 0.00243060665731918,GO:MF,GO:0098531,ligand-activated transcription factor activity,44,48,4,0.08333333333333333,0.09090909090909091 0.00243060665731918,GO:MF,GO:0004879,nuclear receptor activity,44,48,4,0.08333333333333333,0.09090909090909091 0.002485678885259864,GO:MF,GO:0016301,kinase activity,808,48,11,0.22916666666666666,0.013613861386138614 0.0032276898243170926,GO:MF,GO:0071886,"1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding",2,48,2,0.041666666666666664,1.0 0.0032276898243170926,GO:MF,GO:0004666,prostaglandin-endoperoxide synthase activity,2,48,2,0.041666666666666664,1.0 0.0033731650588144997,GO:MF,GO:0097367,carbohydrate derivative binding,2277,48,18,0.375,0.007905138339920948 0.0058091291777147705,GO:MF,GO:0005244,voltage-gated ion channel activity,199,48,6,0.125,0.03015075376884422 0.0059771889445162,GO:MF,GO:0022832,voltage-gated channel activity,200,48,6,0.125,0.03 0.005980811296942062,GO:MF,GO:0003707,steroid hormone receptor activity,55,48,4,0.08333333333333333,0.07272727272727272 0.00724817303217238,GO:MF,GO:0005216,ion channel activity,438,48,8,0.16666666666666666,0.0182648401826484 0.009667104555540674,GO:MF,GO:0005017,platelet-derived growth factor-activated receptor activity,3,48,2,0.041666666666666664,0.6666666666666666 0.009667104555540674,GO:MF,GO:0004517,nitric-oxide synthase activity,3,48,2,0.041666666666666664,0.6666666666666666 0.01095408557766222,GO:MF,GO:0098960,postsynaptic neurotransmitter receptor activity,64,48,4,0.08333333333333333,0.0625 0.012832510628423478,GO:MF,GO:0032559,adenyl ribonucleotide binding,1563,48,14,0.2916666666666667,0.008957133717210493 0.01306184250447895,GO:MF,GO:0016772,"transferase activity, transferring phosphorus-containing groups",964,48,11,0.22916666666666666,0.011410788381742738 0.013632992160946156,GO:MF,GO:0017134,fibroblast growth factor binding,23,48,3,0.0625,0.13043478260869565 0.013632992160946156,GO:MF,GO:0005248,voltage-gated sodium channel activity,23,48,3,0.0625,0.13043478260869565 0.013632992160946156,GO:MF,GO:0030552,cAMP binding,23,48,3,0.0625,0.13043478260869565 0.013782499143651972,GO:MF,GO:0030554,adenyl nucleotide binding,1573,48,14,0.2916666666666667,0.008900190718372537 0.015500635649948528,GO:MF,GO:0015267,channel activity,487,48,8,0.16666666666666666,0.01642710472279261 0.015728527125122533,GO:MF,GO:0022803,passive transmembrane transporter activity,488,48,8,0.16666666666666666,0.01639344262295082 0.017523388186944506,GO:MF,GO:0003824,catalytic activity,5875,48,29,0.6041666666666666,0.004936170212765958 0.019302337216575535,GO:MF,GO:0034617,tetrahydrobiopterin binding,4,48,2,0.041666666666666664,0.5 0.025721364857270685,GO:MF,GO:0042578,phosphoric ester hydrolase activity,382,48,7,0.14583333333333334,0.01832460732984293 0.029518926064205923,GO:MF,GO:0032555,purine ribonucleotide binding,1916,48,15,0.3125,0.007828810020876827 0.03039911774169832,GO:MF,GO:0097159,organic cyclic compound binding,6386,48,30,0.625,0.004697776385844034 0.0317311813720303,GO:MF,GO:0017076,purine nucleotide binding,1928,48,15,0.3125,0.007780082987551867 0.0321175385878712,GO:MF,GO:0086006,voltage-gated sodium channel activity involved in cardiac muscle cell action potential,5,48,2,0.041666666666666664,0.4 0.04809691702518004,GO:MF,GO:0008131,primary amine oxidase activity,6,48,2,0.041666666666666664,0.3333333333333333 0.04809691702518004,GO:MF,GO:0003958,NADPH-hemoprotein reductase activity,6,48,2,0.041666666666666664,0.3333333333333333 0.04809691702518004,GO:MF,GO:0044323,retinoic acid-responsive element binding,6,48,2,0.041666666666666664,0.3333333333333333 2.740036134680792e-08,KEGG,KEGG:04726,Serotonergic synapse,113,44,10,0.22727272727272727,0.08849557522123894 6.274579276446492e-07,KEGG,KEGG:05200,Pathways in cancer,529,44,16,0.36363636363636365,0.030245746691871456 1.6878709369791616e-06,KEGG,KEGG:05032,Morphine addiction,89,44,8,0.18181818181818182,0.0898876404494382 2.0865167973857037e-05,KEGG,KEGG:04151,PI3K-Akt signaling pathway,353,44,12,0.2727272727272727,0.0339943342776204 2.710965155364233e-05,KEGG,KEGG:04014,Ras signaling pathway,231,44,10,0.22727272727272727,0.04329004329004329 2.7844356045965832e-05,KEGG,KEGG:04010,MAPK signaling pathway,294,44,11,0.25,0.03741496598639456 0.0001505033497466216,KEGG,KEGG:05230,Central carbon metabolism in cancer,70,44,6,0.13636363636363635,0.08571428571428572 0.00030748315174975816,KEGG,KEGG:01521,EGFR tyrosine kinase inhibitor resistance,79,44,6,0.13636363636363635,0.0759493670886076 0.0008707601672000977,KEGG,KEGG:04080,Neuroactive ligand-receptor interaction,339,44,10,0.22727272727272727,0.029498525073746312 0.00119787202899603,KEGG,KEGG:04015,Rap1 signaling pathway,210,44,8,0.18181818181818182,0.0380952380952381 0.0014699577165886673,KEGG,KEGG:04024,cAMP signaling pathway,216,44,8,0.18181818181818182,0.037037037037037035 0.004905332554764535,KEGG,KEGG:00230,Purine metabolism,128,44,6,0.13636363636363635,0.046875 0.0073877202697477835,KEGG,KEGG:04020,Calcium signaling pathway,200,44,7,0.1590909090909091,0.035 0.0084977812524923,KEGG,KEGG:04540,Gap junction,88,44,5,0.11363636363636363,0.056818181818181816 0.010638190605478057,KEGG,KEGG:04810,Regulation of actin cytoskeleton,212,44,7,0.1590909090909091,0.0330188679245283 0.010714749115479132,KEGG,KEGG:00330,Arginine and proline metabolism,49,44,4,0.09090909090909091,0.08163265306122448 0.020423459205468186,KEGG,KEGG:04928,"Parathyroid hormone synthesis, secretion and action",106,44,5,0.11363636363636363,0.04716981132075472 0.022110328843668908,KEGG,KEGG:04370,VEGF signaling pathway,59,44,4,0.09090909090909091,0.06779661016949153 0.023257872987632686,KEGG,KEGG:05145,Toxoplasmosis,109,44,5,0.11363636363636363,0.045871559633027525 0.03605990211036679,KEGG,KEGG:05221,Acute myeloid leukemia,67,44,4,0.09090909090909091,0.05970149253731343 0.04743975556153799,KEGG,KEGG:05140,Leishmaniasis,72,44,4,0.09090909090909091,0.05555555555555555 9.901568091027293e-06,REAC,REAC:R-HSA-375280,Amine ligand-binding receptors,42,48,6,0.125,0.14285714285714285 2.8691647200744427e-05,REAC,REAC:R-HSA-162582,Signal Transduction,2735,48,30,0.625,0.010968921389396709 0.000719599530762204,REAC,REAC:R-HSA-392154,Nitric oxide stimulates guanylate cyclase,21,48,4,0.08333333333333333,0.19047619047619047 0.0009349894626381172,REAC,REAC:R-HSA-6811558,"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling",89,48,6,0.125,0.06741573033707865 0.0014565431773851157,REAC,REAC:R-HSA-199418,Negative regulation of the PI3K/AKT network,96,48,6,0.125,0.0625 0.0028124626262259903,REAC,REAC:R-HSA-2219530,Constitutive Signaling by Aberrant PI3K in Cancer,62,48,5,0.10416666666666667,0.08064516129032258 0.003208853929473274,REAC,REAC:R-HSA-6785807,Interleukin-4 and Interleukin-13 signaling,110,48,6,0.125,0.05454545454545454 0.0032145712775122287,REAC,REAC:R-HSA-418594,G alpha (i) signalling events,400,48,10,0.20833333333333334,0.025 0.004474224470479263,REAC,REAC:R-HSA-373076,Class A/1 (Rhodopsin-like receptors),327,48,9,0.1875,0.027522935779816515 0.006420781722487716,REAC,REAC:R-HSA-390666,Serotonin receptors,12,48,3,0.0625,0.25 0.006936910885425954,REAC,REAC:R-HSA-141333,Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB,2,48,2,0.041666666666666664,1.0 0.009401718890567179,REAC,REAC:R-HSA-5663202,Diseases of signal transduction by growth factor receptors and second messengers,359,48,9,0.1875,0.025069637883008356 0.011395305182581758,REAC,REAC:R-HSA-383280,Nuclear Receptor transcription pathway,41,48,4,0.08333333333333333,0.0975609756097561 0.011395305182581758,REAC,REAC:R-HSA-5576892,Phase 0 - rapid depolarisation,41,48,4,0.08333333333333333,0.0975609756097561 0.016469211443105692,REAC,REAC:R-HSA-2219528,PI3K/AKT Signaling in Cancer,89,48,5,0.10416666666666667,0.056179775280898875 0.01725723120721685,REAC,REAC:R-HSA-9006934,Signaling by Receptor Tyrosine Kinases,486,48,10,0.20833333333333334,0.0205761316872428 0.017379260563292614,REAC,REAC:R-HSA-111885,Opioid Signalling,90,48,5,0.10416666666666667,0.05555555555555555 0.018733035587352606,REAC,REAC:R-HSA-1280215,Cytokine Signaling in Immune system,830,48,13,0.2708333333333333,0.01566265060240964 0.020750667169081655,REAC,REAC:R-HSA-140179,Amine Oxidase reactions,3,48,2,0.041666666666666664,0.6666666666666666 0.02147359986425969,REAC,REAC:R-HSA-388396,GPCR downstream signalling,1100,48,15,0.3125,0.013636363636363636 0.041381584992195956,REAC,REAC:R-HSA-9018683,Biosynthesis of DPA-derived SPMs,4,48,2,0.041666666666666664,0.5 0.041381584992195956,REAC,REAC:R-HSA-9025094,Biosynthesis of DPAn-3 SPMs,4,48,2,0.041666666666666664,0.5 0.0436124176435557,REAC,REAC:R-HSA-372790,Signaling by GPCR,1170,48,15,0.3125,0.01282051282051282