Gene,DrugBank ID,Score,Drug Name,Drug Status
KIT,DB09079,0.922945011445048,Nintedanib,FDA approved
RET,DB09079,0.6028132126085418,Nintedanib,FDA approved
ABL1,DB09079,0.4583205775549394,Nintedanib,FDA approved
PDGFRB,DB08901,0.8678634921711473,Ponatinib,FDA approved
FLT1,DB08901,0.6582459695355466,Ponatinib,FDA approved
FLT4,DB08901,0.6306009040896413,Ponatinib,FDA approved
GRIN1,DB01520,0.8391205720677445,Tenocyclidine,experimental
UQCR11,DB04141,0.8381505728165329,"2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol",experimental
PDGFRB,DB09078,0.8173361047999546,Lenvatinib,FDA approved
FLT3,DB09078,0.4942036106142347,Lenvatinib,FDA approved
ABL1,DB09078,0.3680954656879009,Lenvatinib,FDA approved
PDGFRA,DB00398,0.7815927547170162,Sorafenib,FDA approved
FGFR2,DB00398,0.5366580378528232,Sorafenib,FDA approved
FGFR3,DB00398,0.4550444407208658,Sorafenib,FDA approved
ABL1,DB00398,0.3492208315165226,Sorafenib,FDA approved
KCNA1,DB01159,0.7028340645423319,Halothane,FDA approved
GRIA1,DB01159,0.6445089751073723,Halothane,FDA approved
GRIN2D,DB01159,0.3416294862035269,Halothane,FDA approved
HTR7,DB00334,0.7020125351014783,Olanzapine,FDA approved
ADRA1D,DB00334,0.3447843578579349,Olanzapine,FDA approved
KDR,DB00619,0.6982283173795807,Imatinib,FDA approved
FGFR1,DB00619,0.41793632440107614,Imatinib,FDA approved
FLT1,DB00619,0.4146918606575598,Imatinib,FDA approved
FLT4,DB00619,0.393598373063348,Imatinib,FDA approved
FGFR2,DB00619,0.36032508713933503,Imatinib,FDA approved
GRIN3B,DB06151,0.6946545770116956,Acetylcysteine,FDA approved
GRIN2C,DB06151,0.6854662331704116,Acetylcysteine,FDA approved
HTR1D,DB00247,0.6733441246332729,Methysergide,FDA approved
HTR6,DB00247,0.4242731561420504,Methysergide,FDA approved
DRD4,DB00502,0.6726000496172466,Haloperidol,FDA approved
CHRM4,DB00502,0.44576648979075656,Haloperidol,FDA approved
DRD5,DB00543,0.6672812856146708,Amoxapine,FDA approved
HTR1D,DB00543,0.5842744587395218,Amoxapine,FDA approved
HTR1E,DB00543,0.4182919729969694,Amoxapine,FDA approved
OPRK1,DB00956,0.6590664461321245,Hydrocodone,FDA approved
OPRD1,DB00652,0.6552770732271613,Pentazocine,FDA approved
FLT1,DB12147,0.6517103312721683,Erdafitinib,FDA approved
FLT4,DB12147,0.6174913249962356,Erdafitinib,FDA approved
FLT3,DB12147,0.4804345587968383,Erdafitinib,FDA approved
ABL1,DB12147,0.36777244159310296,Erdafitinib,FDA approved
GRIN3A,DB00454,0.6511078334535195,Meperidine,FDA approved
GRIN3B,DB00454,0.6354506778095738,Meperidine,FDA approved
OPRD1,DB00454,0.6110851405622333,Meperidine,FDA approved
FLT3,DB08896,0.6394142613390872,Regorafenib,FDA approved
FGFR3,DB08896,0.6186888592511602,Regorafenib,FDA approved
CSF1R,DB08896,0.3883377434989732,Regorafenib,FDA approved
FGFR4,DB08896,0.3804548378253849,Regorafenib,FDA approved
DRD4,DB06148,0.6379693204902125,Mianserin,FDA approved
NOS3,DB03449,0.6372379118545712,N-(4-{2-[(3-chlorobenzyl)amino]ethyl}phenyl)thiophene-2-carboximidamide,experimental
OPRD1,DB11186,0.6312678334607021,Pentoxyverine,FDA approved
NOS3,DB02644,0.6304877678733384,N-omega-propyl-L-arginine,experimental
RXRA,DB00799,0.6247914735380692,Tazarotene,FDA approved
RXRG,DB00799,0.5343961455982731,Tazarotene,FDA approved
OPRK1,DB01444,0.6218613143093082,Dimethylthiambutene,experimental
OPRK1,DB01081,0.6208345770813274,Diphenoxylate,FDA approved
OPRD1,DB01209,0.619207035052739,Dezocine,FDA approved
OPRK1,DB01192,0.6180005984543078,Oxymorphone,FDA approved
SLC18A2,DB00852,0.6168898345625952,Pseudoephedrine,FDA approved
OPRD1,DB06800,0.6151279601644829,Methylnaltrexone,FDA approved
GABRA6,DB00546,0.6055700355676211,Adinazolam,experimental
GABRA4,DB00546,0.5998912866106579,Adinazolam,experimental
GABRA6,DB01594,0.6053538873934691,Cinolazepam,experimental
GABRA4,DB01594,0.5995903556867439,Cinolazepam,experimental
GABRA6,DB01567,0.6045125445006626,Fludiazepam,experimental
GABRA4,DB01567,0.5987382748881949,Fludiazepam,experimental
GABRA6,DB01559,0.6042867171437275,Clotiazepam,FDA approved
GABRA4,DB01559,0.5985329356835493,Clotiazepam,FDA approved
GABRA4,DB13872,0.593481791523879,Lormetazepam,FDA approved
GABRA6,DB13872,0.5848385063358894,Lormetazepam,FDA approved
SCN8A,DB00909,0.5922346204089245,Zonisamide,FDA approved
SCN10A,DB00909,0.4242913330162753,Zonisamide,FDA approved
ADORA2A,DB09283,0.5919107730027853,Trapidil,experimental
ADORA1,DB09283,0.556723753036467,Trapidil,experimental
ADORA2B,DB09283,0.3907081914064141,Trapidil,experimental
DRD5,DB00363,0.5798137390720702,Clozapine,FDA approved
GABRB3,DB01587,0.5767185820963191,Ketazolam,FDA approved
GABRB2,DB01587,0.5624351954057072,Ketazolam,FDA approved
GABRG2,DB01587,0.4252714602698749,Ketazolam,FDA approved
GABRA2,DB00395,0.573476532300045,Carisoprodol,FDA approved
GABRA4,DB00395,0.4635465628523667,Carisoprodol,FDA approved
GABRA6,DB00395,0.4595578146548965,Carisoprodol,FDA approved
ADRA1D,DB01579,0.570834484861912,Phendimetrazine,FDA approved
SLC6A2,DB01238,0.5640523336146256,Aripiprazole,FDA approved
ADRB3,DB01238,0.3579995408200593,Aripiprazole,FDA approved
FGFR1,DB01268,0.5620668765992091,Sunitinib,FDA approved
RET,DB01268,0.5425466928412308,Sunitinib,FDA approved
FGFR2,DB01268,0.4788305942274216,Sunitinib,FDA approved
FGFR3,DB01268,0.4056860034078481,Sunitinib,FDA approved
FGFR1,DB06589,0.5617750272045363,Pazopanib,FDA approved
RET,DB06589,0.5416939766670257,Pazopanib,FDA approved
FGFR2,DB06589,0.4788362380434206,Pazopanib,FDA approved
FLT3,DB06589,0.41761819408348216,Pazopanib,FDA approved
OPRK1,DB00333,0.5598652242149355,Methadone,FDA approved
PDE4B,DB07954,0.5596562146271418,3-isobutyl-1-methyl-7H-xanthine,experimental
PDE4A,DB07954,0.4843984725096611,3-isobutyl-1-methyl-7H-xanthine,experimental
HTR2C,DB09225,0.5580258926657172,Zotepine,FDA approved
SLC6A3,DB09225,0.4214750913988476,Zotepine,FDA approved
GABRA5,DB09166,0.5567997518372068,Etizolam,experimental
GABRA4,DB09166,0.4658674523666075,Etizolam,experimental
GABRA6,DB09166,0.4590970155661812,Etizolam,experimental
GRIN2A,DB01173,0.5496266418168404,Orphenadrine,FDA approved
GRIN2B,DB01173,0.5414161870718786,Orphenadrine,FDA approved
GRIN2C,DB01173,0.4930659306544296,Orphenadrine,FDA approved
SLC6A4,DB01173,0.3468100801922325,Orphenadrine,FDA approved
GABRA5,DB00425,0.5485712658333797,Zolpidem,FDA approved
GABRA4,DB00425,0.4619830791561818,Zolpidem,FDA approved
GABRA6,DB00425,0.4554126305315175,Zolpidem,FDA approved
CA4,DB01119,0.544097634704894,Diazoxide,FDA approved
DRD4,DB11274,0.5433787685184601,Dihydro-alpha-ergocryptine,FDA approved
GABRA4,DB01198,0.5358499455075796,Zopiclone,FDA approved
GABRA6,DB01198,0.5271487957867385,Zopiclone,FDA approved
GABRG2,DB01198,0.3410127454610186,Zopiclone,FDA approved
ADRB3,DB01151,0.531758912281594,Desipramine,FDA approved
SLC6A4,DB00422,0.530579919869952,Methylphenidate,FDA approved
SLC6A3,DB09068,0.5301487898189663,Vortioxetine,FDA approved
HTR1D,DB09068,0.4426482427712219,Vortioxetine,FDA approved
HTR6,DB09068,0.3885693016891846,Vortioxetine,FDA approved
ADRB2,DB09068,0.3624182312316222,Vortioxetine,FDA approved
HTR1D,DB06216,0.5295812429061528,Asenapine,FDA approved
DRD5,DB06216,0.4880804946863265,Asenapine,FDA approved
SLC6A4,DB00937,0.5244740861123026,Diethylpropion,FDA approved
SLC6A4,DB00830,0.5228976746022154,Phenmetrazine,FDA approved
HTR1B,DB04948,0.522136601973407,Lofexidine,FDA approved
HTR2A,DB04948,0.5035866111025971,Lofexidine,FDA approved
SLC6A4,DB14754,0.5221324578641937,Solriamfetol,FDA approved
SCN4A,DB00252,0.5160856391459542,Phenytoin,FDA approved
SCN10A,DB00252,0.4425306096350165,Phenytoin,FDA approved
HTR1D,DB00904,0.5153867508955031,Ondansetron,FDA approved
OPRD1,DB00904,0.3601683696680901,Ondansetron,FDA approved
CACNA2D1,DB01244,0.5137774743750856,Bepridil,FDA approved
CACNA1C,DB01244,0.3855979452388653,Bepridil,FDA approved
CACNA1S,DB00622,0.5045696662703539,Nicardipine,FDA approved
TNNC1,DB00622,0.3442906739989827,Nicardipine,FDA approved
PTGS2,DB00711,0.5040670871653188,Diethylcarbamazine,FDA approved
SLC6A4,DB00934,0.5027915769165809,Maprotiline,FDA approved
SLC6A3,DB01364,0.5005167246051592,Ephedrine,FDA approved
SLC6A4,DB01156,0.4983754526263505,Bupropion,FDA approved
PTGS1,DB00233,0.4965661410433855,Aminosalicylic acid,FDA approved
SLC6A2,DB01472,0.4906809491342139,4-Methoxyamphetamine,experimental
CACNB2,DB09229,0.4876896564648466,Aranidipine,experimental
CACNB1,DB09229,0.3443600227311464,Aranidipine,experimental
CA3,DB00562,0.487279445158579,Benzthiazide,FDA approved
CACNB2,DB04920,0.486660584576106,Clevidipine,FDA approved
CACNB1,DB04920,0.3645945142321316,Clevidipine,FDA approved
DRD3,DB00372,0.4859925350853708,Thiethylperazine,FDA approved
DRD5,DB00372,0.44705349687968,Thiethylperazine,FDA approved
PTGS1,DB09285,0.4853492833310533,Morniflumate,experimental
PTGS2,DB08814,0.4803203192766918,Triflusal,FDA approved
NOS3,DB08814,0.4204976531560123,Triflusal,FDA approved
ADRA2B,DB01608,0.4801748262070268,Periciazine,FDA approved
ADRA1A,DB01608,0.3613500426708354,Periciazine,FDA approved
CA3,DB00774,0.4801515509150362,Hydroflumethiazide,FDA approved
PPARD,DB03756,0.4797555596798328,Doconexent,FDA approved
RARG,DB03756,0.4021971593739682,Doconexent,FDA approved
SLC6A3,DB06204,0.478593946866517,Tapentadol,FDA approved
ADRA2B,DB00413,0.4776495401958508,Pramipexole,FDA approved
HTR2C,DB09167,0.4770996122246536,Dosulepin,FDA approved
SLC6A3,DB09167,0.3741453515253668,Dosulepin,FDA approved
NOS2,DB02994,0.476795018684991,Cacodylic acid,experimental
PTGS1,DB01041,0.4752259014099817,Thalidomide,FDA approved
CACNA1I,DB00661,0.4732729894520957,Verapamil,FDA approved
CACNA2D2,DB00661,0.3580415325999731,Verapamil,FDA approved
SLC6A2,DB00661,0.3461680277151292,Verapamil,FDA approved
CHRM4,DB06709,0.4723335848975445,Methacholine,FDA approved
CHRM4,DB13720,0.4718274083576021,Diphemanil,FDA approved
CHRM4,DB01062,0.4717961912892185,Oxybutynin,FDA approved
CHRM4,DB04365,0.4717711234152579,Arecoline,experimental
CHRM4,DB00517,0.4717123377996712,Anisotropine methylbromide,FDA approved
CHRM4,DB00185,0.4716509793027103,Cevimeline,FDA approved
CHRM4,DB00462,0.4714504177760489,Methscopolamine bromide,FDA approved
CHRM4,DB01231,0.4711892659100012,Diphenidol,FDA approved
CHRM4,DB00332,0.4703932341708183,Ipratropium,FDA approved
CHRM4,DB00986,0.4703582627295832,Glycopyrronium,FDA approved
CHRM4,DB04843,0.469616187493543,Mepenzolate,FDA approved
CHRM4,DB00383,0.4687609980651746,Oxyphencyclimine,FDA approved
CHRM4,DB01337,0.4679455304639805,Pancuronium,FDA approved
CHRM4,DB09300,0.4679170091812418,Butylscopolamine,FDA approved
CHRM4,DB01338,0.46770052705443704,Pipecuronium,FDA approved
PTGS2,DB04557,0.4672641643691125,Arachidonic Acid,experimental
PPARD,DB04557,0.376917493761464,Arachidonic Acid,experimental
ADRA2B,DB00692,0.4669554862869762,Phentolamine,FDA approved
PTGS1,DB11327,0.4663598023481434,Dipyrithione,FDA approved
NOS3,DB11327,0.4012093448936062,Dipyrithione,FDA approved
PTGS1,DB00533,0.4656656457768098,Rofecoxib,FDA approved
PTGS1,DB04743,0.4648470071412944,Nimesulide,FDA approved
CHRM4,DB00202,0.4646016929062489,Succinylcholine,FDA approved
RARG,DB00307,0.4644291511839269,Bexarotene,FDA approved
RARA,DB00307,0.3791223205282103,Bexarotene,FDA approved
RARB,DB00307,0.3785541904366476,Bexarotene,FDA approved
MAOB,DB00805,0.4643090265265831,Minaprine,FDA approved
PTGS1,DB00480,0.4640072859931287,Lenalidomide,FDA approved
PTGS1,DB08910,0.4630234150194956,Pomalidomide,FDA approved
PTGS1,DB08439,0.4629366346419445,Parecoxib,FDA approved
ADRA1D,DB01149,0.4628525645484322,Nefazodone,FDA approved
PTGS2,DB02110,0.4627244138043892,Protoporphyrin Ix Containing Co,experimental
PTGS1,DB13167,0.4623586084860276,Alclofenac,FDA approved
PTGS1,DB09217,0.4622855419065147,Firocoxib,experimental
PTGS2,DB03753,0.4616301335403628,Flurbiprofen Methyl Ester,experimental
PTGS2,DB03752,0.4616126740100792,P-(2'-Iodo-5'-Thenoyl)Hydrotropic Acid,experimental
PTGS1,DB01628,0.4614483504500839,Etoricoxib,FDA approved
PTGS2,DB02198,0.4614384939961514,2-Bromoacetyl Group,experimental
PTGS2,DB02047,0.4611929127681013,"2-(1,1'-Biphenyl-4-Yl)Propanoic Acid",experimental
PTGS1,DB03866,0.4607544840088965,Prostaglandin G2,experimental
HTR1B,DB00726,0.4605481842307141,Trimipramine,FDA approved
ADRA1D,DB00726,0.4441227130466984,Trimipramine,FDA approved
PTGS2,DB02773,0.4604674851744943,(3-Chloro-4-Propoxy-Phenyl)-Acetic Acid,experimental
NOS3,DB03366,0.4603472559650041,Imidazole,experimental
UQCRC1,DB07636,0.4602600265725891,"5-Heptyl-6-hydroxy-1,3-benzothiazole-4,7-dione",experimental
UQCRQ,DB07636,0.4539288979296805,"5-Heptyl-6-hydroxy-1,3-benzothiazole-4,7-dione",experimental
UQCRH,DB07636,0.4538969115818803,"5-Heptyl-6-hydroxy-1,3-benzothiazole-4,7-dione",experimental
UQCRC2,DB07636,0.4535148617783047,"5-Heptyl-6-hydroxy-1,3-benzothiazole-4,7-dione",experimental
UQCR11,DB07636,0.3983592868150127,"5-Heptyl-6-hydroxy-1,3-benzothiazole-4,7-dione",experimental
PTGS2,DB03667,0.4601324945713456,Acetic Acid Salicyloyl-Amino-Ester,experimental
PTGS1,DB03477,0.4597931921523888,1-Phenylsulfonamide-3-Trifluoromethyl-5-Parabromophenylpyrazole,experimental
PTGS2,DB01837,0.4595554038935066,O-acetyl-L-serine,experimental
PTGS2,DB07983,0.4581467901048064,1-(4-IODOBENZOYL)-5-METHOXY-2-METHYL INDOLE-3-ACETIC ACID,experimental
PTGS2,DB04817,0.45794306326041995,Metamizole,FDA approved
ADH1C,DB04464,0.456845422708649,N-Formylmethionine,experimental
CES1,DB04464,0.4025222323564817,N-Formylmethionine,experimental
PLA2G1B,DB04464,0.3677779129361678,N-Formylmethionine,experimental
PTGS1,DB00482,0.4554922204105564,Celecoxib,FDA approved
PTGS1,DB00580,0.4549243695120826,Valdecoxib,FDA approved
ADRA2B,DB00320,0.4544951911890827,Dihydroergotamine,FDA approved
HTR1A,DB00320,0.39541311929214096,Dihydroergotamine,FDA approved
CHRM4,DB00434,0.4540215303876962,Cyproheptadine,FDA approved
HTR6,DB00434,0.3942423145103254,Cyproheptadine,FDA approved
CHRM4,DB01226,0.4536012103951903,Mivacurium,FDA approved
SLC6A4,DB01576,0.4522980654021979,Dextroamphetamine,FDA approved
ADRA1D,DB01576,0.39031018896645897,Dextroamphetamine,FDA approved
ADRB1,DB09273,0.4519781061152933,Doxofylline,experimental
CHRM4,DB00280,0.4506862086965554,Disopyramide,FDA approved
PTGS2,DB07984,0.4506165705513418,2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1S)-1-(hydroxymethyl)propyl]acetamide,experimental
PTGS2,DB07981,0.450571087394353,2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1R)-1-(hydroxymethyl)propyl]acetamide,experimental
DRD5,DB00508,0.4503211872002773,Triflupromazine,FDA approved
HTR2A,DB00508,0.3723729084769501,Triflupromazine,FDA approved
NOS2,DB00360,0.4499221384664986,Sapropterin,FDA approved
ADRB3,DB00668,0.4493747982169535,Epinephrine,FDA approved
PTGS2,DB00350,0.4481370546062747,Minoxidil,FDA approved
CALM1,DB00270,0.44493275756718426,Isradipine,FDA approved
NOS3,DB04400,0.4449252884451837,"L-erythro-7,8-dihydrobiopterin",experimental
MAOA,DB02643,0.4421908467538239,"N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-Propanesulfonate",experimental
ADRB3,DB01359,0.44215708321329655,Penbutolol,FDA approved
HTR1D,DB01359,0.4183440613794277,Penbutolol,FDA approved
CHRM4,DB00193,0.44154069172812427,Tramadol,FDA approved
PIK3CG,DB04395,0.4404159902640465,Phosphoaminophosphonic Acid-Adenylate Ester,experimental
PDPK1,DB04395,0.4354391076153849,Phosphoaminophosphonic Acid-Adenylate Ester,experimental
CHRM4,DB06153,0.43991520812400703,Pizotifen,FDA approved
NOS2,DB03963,0.4397970794570493,S-(Dimethylarsenic)Cysteine,experimental
MAOA,DB01367,0.4394714276032888,Rasagiline,FDA approved
MAOA,DB02509,0.4390866092546825,Farnesol,experimental
ADRB1,DB00449,0.4389298291210754,Dipivefrin,FDA approved
CA4,DB01325,0.4377415321496637,Quinethazone,FDA approved
SCN1A,DB00281,0.4363035364170011,Lidocaine,FDA approved
SCN3A,DB00281,0.43461847154658223,Lidocaine,FDA approved
SCN8A,DB00281,0.4154909682400635,Lidocaine,FDA approved
CHRM4,DB00599,0.4360970292508033,Thiopental,FDA approved
GRIN2D,DB00949,0.4359641462770879,Felbamate,FDA approved
GRIN1,DB00949,0.4328378823498617,Felbamate,FDA approved
GRIN3B,DB00949,0.4077914892064933,Felbamate,FDA approved
GRIN2C,DB00949,0.3891026258837383,Felbamate,FDA approved
MAOB,DB07641,0.435323470367316,"Decyl(dimethyl)phosphine oxide",experimental
MAOA,DB08480,0.4348630088415941,"4-HYDROXY-N-PROPARGYL-1(R)-AMINOINDAN",experimental
ADRB2,DB08558,0.4348471879287049,"2-HYDROXYMETHYL-6-OCTYLSULFANYL-TETRAHYDRO-PYRAN-3,4,5-TRIOL",experimental
MAOA,DB03894,0.4344509787627401,"N-Propargyl-1(S)-Aminoindan",experimental
MAOA,DB04677,0.43438285700263385,"N-METHYL-N-[(1R)-1-METHYL-2-PHENYLETHYL]PROP-2-EN-1-AMINE",experimental
MAOA,DB02095,0.4341499391063007,Isatin,experimental
MAOA,DB08516,0.4340904352554424,"(S)-(+)-2-[4-(FLUOROBENZYLOXY-BENZYLAMINO)PROPIONAMIDE]",experimental
MAOA,DB07513,0.4340719250726871,"7-[(3-CHLOROBENZYL)OXY]-4-[(METHYLAMINO)METHYL]-2H-CHROMEN-2-ONE",experimental
MAOA,DB04307,0.433986726980678,"5-Hydroxy-N-Propargyl-1(R)-Aminoindan",experimental
MAOA,DB02211,0.4338525582081688,"N-Methyl-N-Propargyl-1(R)-Aminoindan",experimental
ADRA2B,DB00370,0.4336899209399165,Mirtazapine,FDA approved
MAOB,DB07919,0.43346667971721,"7-METHOXY-1-METHYL-9H-BETA-CARBOLINE",experimental
MAOA,DB06654,0.4333458734131848,Safinamide,FDA approved
MAOB,DB04017,0.43332595189423617,Clorgiline,experimental
MAOA,DB07512,0.4329240466390421,7-[(3-CHLOROBENZYL)OXY]-2-OXO-2H-CHROMENE-4-CARBALDEHYDE,experimental
MAOA,DB08082,0.43290355160971583,N-(2-AMINOETHYL)-P-CHLOROBENZAMIDE,experimental
MAOB,DB13876,0.4328640122913009,Brofaromine,experimental
GABRG2,DB00683,0.4320162000702064,Midazolam,FDA approved
NOS2,DB03707,0.4319803480232348,S-Ethyl-N-Phenyl-Isothiourea,experimental
NOS2,DB02027,0.4319688055820389,N-{(4S)-4-Amino-5-[(2-aminoethyl)amino]pentyl}-N'-nitroguanidine,experimental
ADRB2,DB08347,0.4314234156504783,4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile,experimental
ADRB2,DB09351,0.4313901202222351,Levobetaxolol,FDA approved
CACNB2,DB00568,0.431053109398368,Cinnarizine,FDA approved
CACNB1,DB00568,0.3872832725439711,Cinnarizine,FDA approved
CACNB4,DB00568,0.38080494237059537,Cinnarizine,FDA approved
CACNB3,DB00568,0.3805038993896145,Cinnarizine,FDA approved
ADRA1D,DB00679,0.43091194794589466,Thioridazine,FDA approved
ADRB2,DB01297,0.4308578397465265,Practolol,FDA approved
ADRB2,DB00187,0.4304226585366324,Esmolol,FDA approved
CA4,DB00880,0.4298351644741643,Chlorothiazide,FDA approved
ADRB1,DB11587,0.4296021567423939,Etafedrine,FDA approved
ADRB1,DB00816,0.4295878994843432,Orciprenaline,FDA approved
ADRB1,DB13139,0.4293594274979217,Levosalbutamol,FDA approved
RXRB,DB12808,0.42933245015200655,Trifarotene,FDA approved
RXRA,DB12808,0.3993327546752,Trifarotene,FDA approved
RXRG,DB12808,0.3498292920062245,Trifarotene,FDA approved
ADRB1,DB00867,0.4292638020035265,Ritodrine,FDA approved
ADRB1,DB07543,0.4288325834665708,(2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol,experimental
NOS2,DB01821,0.4287788041313112,"L-N(omega)-Nitroarginine-2,4-L-diaminobutyric amide",experimental
ADRB1,DB01366,0.4286615414799208,Procaterol,FDA approved
ADRB1,DB01274,0.4286073116954985,Arformoterol,FDA approved
NOS2,DB04223,0.4285326158682489,Nitroarginine,experimental
MAOB,DB09245,0.4285052842878673,Toloxatone,experimental
ADRB1,DB06814,0.42847231368385214,Protokylol,FDA approved
ADRB1,DB09082,0.4284681558505546,Vilanterol,FDA approved
ADRB1,DB05039,0.4270262372993249,Indacaterol,FDA approved
ADRB2,DB13781,0.4263569833606765,Xamoterol,FDA approved
ADRB1,DB09080,0.4256066156915592,Olodaterol,FDA approved
CALM1,DB01054,0.42556711557276616,Nitrendipine,FDA approved
DRD5,DB01239,0.4245213075476036,Chlorprothixene,FDA approved
GRIA2,DB01373,0.4238984486115818,Calcium,FDA approved
DHFR,DB01373,0.4070746697941634,Calcium,FDA approved
KCNA1,DB01373,0.3881073172743411,Calcium,FDA approved
DHODH,DB01373,0.3837626048717698,Calcium,FDA approved
NOS2,DB02077,0.4238961388482067,L-N(omega)-nitroarginine-(4R)-amino-L-proline amide,experimental
CHRM4,DB00477,0.4238482950788166,Chlorpromazine,FDA approved
CA3,DB01021,0.4236788101021171,Trichlormethiazide,FDA approved
ADRA2B,DB09242,0.4229598911766381,Moxonidine,FDA approved
SLC6A3,DB08918,0.42130757216957054,Levomilnacipran,FDA approved
NOS2,DB07244,0.4212767350740236,"5-{4-[(3,5-DIFLUOROBENZYL)AMINO]PHENYL}-6-ETHYLPYRIMIDINE-2,4-DIAMINE",experimental
NOS2,DB08018,0.42085632292203823,"N-{(3S,4S)-4-[(6-AMINO-4-METHYLPYRIDIN-2-YL)METHYL]PYRROLIDIN-3-YL}-N'-(4-CHLOROBENZYL)ETHANE-1,2-DIAMINE",experimental
NOS2,DB08019,0.4208243094693248,"N-{(3R,4S)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}-N'-(3-chlorobenzyl)ethane-1,2-diamine",experimental
KDR,DB12978,0.4197280455128548,Pexidartinib,FDA approved
SLC6A3,DB00344,0.4192774389586929,Protriptyline,FDA approved
HTR1D,DB00960,0.4185220378398744,Pindolol,FDA approved
HTR1D,DB00571,0.41783053843277823,Propranolol,FDA approved
HTR1D,DB08807,0.4175784221388045,Bopindolol,experimental
NOS2,DB02335,0.4166815771843247,2-Aminothiazoline,experimental
NOS2,DB02589,0.4165058742739797,Se-Ethyl-Isoselenourea,experimental
ADRB3,DB00397,0.4162547832115291,Phenylpropanolamine,FDA approved
MAOA,DB04147,0.41599426824318697,Lauryl Dimethylamine-N-Oxide,experimental
NOS2,DB04018,0.4156061780926511,S-Isopropyl-Isothiourea,experimental
NOS2,DB02979,0.4155288094700365,"N1,N14-Bis((S-Methyl)Isothioureido)Tetradecane",experimental
CA3,DB00436,0.4154104287285617,Bendroflumethiazide,FDA approved
ADRB2,DB01118,0.4152827896907989,Amiodarone,FDA approved
MAOA,DB01132,0.4151740352910442,Pioglitazone,FDA approved
NOS2,DB04559,0.4151564106191917,N-(Chlorophenyl)-N'-Hydroxyguanidine,experimental
NOS2,DB07001,0.4151440378171241,"(3S,5E)-3-propyl-3,4-dihydrothieno[2,3-f][1,4]oxazepin-5(2H)-imine",experimental
NOS2,DB02141,0.4151417275302505,"S,S'-(1,4-Phenylene-Bis(1,2-Ethanediyl))Bis-Isothiourea",experimental
NOS2,DB03910,0.4151064999178095,"S,S'-(1,3-Phenylene-Bis(1,2-Ethanediyl))Bis-Isothiourea",experimental
ADRA2B,DB00968,0.4149237406430472,Methyldopa,FDA approved
FLT1,DB06595,0.4146555296370313,Midostaurin,FDA approved
FGFR1,DB06595,0.4096988484630701,Midostaurin,FDA approved
RET,DB06595,0.3941272159173237,Midostaurin,FDA approved
FLT4,DB06595,0.3922516108749052,Midostaurin,FDA approved
FGFR2,DB06595,0.3487210812281685,Midostaurin,FDA approved
NOS2,DB02048,0.4145859326256053,"1,2,4-Triazole-Carboxamidine",experimental
HTR1A,DB00409,0.4141719623409088,Remoxipride,FDA approved
NOS2,DB03065,0.4140802301942833,7-Nitroindazole-2-Carboxamidine,experimental
KDR,DB01254,0.41405503797731696,Dasatinib,FDA approved
PDGFRA,DB01254,0.37825938400543785,Dasatinib,FDA approved
NOS2,DB01833,0.4136151869717553,Canavanine,experimental
ADRA2B,DB00633,0.4135432100345462,Dexmedetomidine,FDA approved
HTR2C,DB04946,0.4134038076012592,Iloperidone,FDA approved
HTR2C,DB01488,0.4133702477711809,Dimethyltryptamine,experimental
GSK3B,DB04522,0.4122519037856968,Dexfosfoserine,experimental
DRD2,DB04908,0.41194823170897577,Flibanserin,FDA approved
ADRA2B,DB11738,0.4119018946717925,Rilmenidine,FDA approved
NOS2,DB03974,0.4115228410317935,L-homoarginine,experimental
NOS2,DB03305,0.41148239502542905,N(G)-Iminoethylornithine,experimental
DRD4,DB00458,0.4106959130158785,Imipramine,FDA approved
DRD3,DB00458,0.3804167089182816,Imipramine,FDA approved
DRD5,DB01267,0.4105761344212436,Paliperidone,FDA approved
HTR1B,DB01267,0.39929801407845456,Paliperidone,FDA approved
ADRA1D,DB01267,0.3964593496453815,Paliperidone,FDA approved
HTR6,DB01267,0.3794396405856328,Paliperidone,FDA approved
HTR1A,DB00998,0.4098883590250961,Frovatriptan,FDA approved
HTR1A,DB00953,0.4095828281962492,Rizatriptan,FDA approved
HTR1A,DB00918,0.4095714356065244,Almotriptan,FDA approved
NOS2,DB02911,0.4094373318537746,"2,4-Diamino-6-Phenyl-5,6,7,8,-Tetrahydropteridine",experimental
ADRA2A,DB00292,0.4081362244502307,Etomidate,FDA approved
HTR6,DB00988,0.40786297271458,Dopamine,FDA approved
DRD5,DB00734,0.40768381515177177,Risperidone,FDA approved
HTR1B,DB00734,0.3993640073096116,Risperidone,FDA approved
ADRA1D,DB00734,0.39358965998709095,Risperidone,FDA approved
HTR6,DB00734,0.3805863436058487,Risperidone,FDA approved
NOS3,DB07003,0.4056592649026811,"(2S)-2-methyl-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine",experimental
ADRB3,DB00127,0.405470708164606,Spermine,experimental
HTR2B,DB01224,0.4044400795848561,Quetiapine,FDA approved
NOS3,DB01835,0.4043288877116554,4R-Fluoro-N6-ethanimidoyl-L-lysine,experimental
NOS3,DB08214,0.4040431423710365,4-(1H-IMIDAZOL-1-YL)PHENOL,experimental
PDE4A,DB00131,0.4030032413985365,Adenosine phosphate,FDA approved
NOS3,DB03953,0.4029803877360668,Thiocitrulline,experimental
SLC6A3,DB00715,0.4017501948784832,Paroxetine,FDA approved
NOS3,DB07389,0.4016868531795764,N-[2-(6-AMINO-4-METHYLPYRIDIN-2-YL)ETHYL]-4-CYANOBENZAMIDE,experimental
HTR2C,DB06016,0.4015790930793947,Cariprazine,FDA approved
CA3,DB09460,0.4011360765280865,Sodium carbonate,FDA approved
NOS2,DB03918,0.3998942748161552,"6S-5,6,7,8-Tetrahydrobiopterin",experimental
MAOB,DB09244,0.3994788231715373,Pirlindole,experimental
ADRA2B,DB09244,0.3655347767747514,Pirlindole,experimental
ADRB3,DB01917,0.3991004039582782,Putrescine,experimental
NOS3,DB02462,0.3988452861942368,Thiocoumarin,experimental
ADRB3,DB03566,0.3981129234135424,Spermidine,experimental
NOS3,DB06879,0.3980447358937058,"5-(4'-AMINO-1'-ETHYL-5',8'-DIFLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLINE]-1-YLCARBONYL)PICOLINONITRILE",experimental
ADRB3,DB00195,0.3978242397558631,Betaxolol,FDA approved
ADRB3,DB01136,0.3977959033202525,Carvedilol,FDA approved
ADRB3,DB00264,0.3977826239367765,Metoprolol,FDA approved
ADRB3,DB00221,0.39767096124753626,Isoetharine,FDA approved
ADRB3,DB01291,0.3976466335362566,Pirbuterol,FDA approved
ADRB3,DB01203,0.3975170764633243,Nadolol,FDA approved
ADRB3,DB00612,0.397487758383395,Bisoprolol,FDA approved
ADRB3,DB01210,0.3973693808117598,Levobunolol,FDA approved
ADRB3,DB09013,0.3973275480887406,Befunolol,experimental
NOS3,DB07007,0.3973144807371765,"(3R)-3-[(1,2,3,4-tetrahydroisoquinolin-7-yloxy)methyl]-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine",experimental
ADRB3,DB01214,0.397254403604971,Metipranolol,FDA approved
PDE4B,DB06842,0.3972428249449649,(4R)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one,experimental
ADRB3,DB00335,0.3972016171714821,Atenolol,FDA approved
ADRB3,DB00598,0.3970248401688665,Labetalol,FDA approved
NOS3,DB07318,0.3967252347931083,"N-[2-(4-AMINO-5,8-DIFLUORO-1,2-DIHYDROQUINAZOLIN-2-YL)ETHYL]-3-FURAMIDE",experimental
PDE5A,DB00651,0.3964884016825175,Dyphylline,FDA approved
PDE3A,DB00651,0.3785523201420629,Dyphylline,FDA approved
DRD4,DB06288,0.3964620154820684,Amisulpride,FDA approved
HTR2C,DB06288,0.3540396845921324,Amisulpride,FDA approved
ADRB3,DB01193,0.3960932823246647,Acebutolol,FDA approved
NR3C2,DB00367,0.3959597625769332,Levonorgestrel,FDA approved
ADRB3,DB00521,0.3956136992364445,Carteolol,FDA approved
CACNA1F,DB00653,0.3950747816846333,Magnesium sulfate,FDA approved
CACNB3,DB00653,0.3455202603466845,Magnesium sulfate,FDA approved
CACNB4,DB00653,0.34415128503326764,Magnesium sulfate,FDA approved
SLC6A2,DB06684,0.3948207582712843,Vilazodone,FDA approved
NOS3,DB07306,0.3947393720694609,ETHYL 4-[(4-CHLOROPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE,experimental
ADRB3,DB00373,0.3945442007150237,Timolol,FDA approved
DRD4,DB00391,0.3943900193165199,Sulpiride,FDA approved
NOS3,DB08750,0.3933730257425509,"1-[4-(AMINOMETHYL)BENZOYL]-5'-FLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLIN]-4'-AMINE",experimental
ADRB1,DB00925,0.3929191705758709,Phenoxybenzamine,FDA approved
NOS3,DB07405,0.3926729827631558,"1-(6-CYANO-3-PYRIDYLCARBONYL)-5',8'-DIFLUOROSPIRO[PIPERIDINE-4,2'(1'H)-QUINAZOLINE]-4'-AMINE",experimental
NR3C2,DB11619,0.3921152379093967,Gestrinone,FDA approved
NOS2,DB03332,0.3918209475584094,"5,6-Cyclic-Tetrahydropteridine",experimental
HTR6,DB00248,0.3909323717490004,Cabergoline,FDA approved
ADRB3,DB00248,0.3453759500823119,Cabergoline,FDA approved
GABRB2,DB00431,0.3905134431253688,Lindane,FDA approved
GABRD,DB00431,0.3857652744716661,Lindane,FDA approved
GABRE,DB00431,0.3631581478360584,Lindane,FDA approved
ADRB3,DB00841,0.389896978608562,Dobutamine,FDA approved
NOS3,DB07008,0.3891374073156642,"4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]PYRIMIDINE",experimental
PDE4D,DB00806,0.3889918359401484,Pentoxifylline,FDA approved
PDE3A,DB00806,0.3580402153301916,Pentoxifylline,FDA approved
NOS3,DB07029,0.3877353172992019,"4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]-6-METHYLPYRIMIDINE",experimental
PGR,DB00624,0.3876492841788877,Testosterone,FDA approved
ADRA1D,DB01622,0.3875752495148092,Thioproperazine,experimental
PGR,DB13944,0.3873308563800129,Testosterone enanthate,FDA approved
PGR,DB13943,0.3872830764165358,Testosterone cypionate,FDA approved
PGR,DB13946,0.3872004438475055,Testosterone undecanoate,FDA approved
PGR,DB13951,0.3871690884077876,Stanolone acetate,experimental
ADRA1D,DB01614,0.38712820912332063,Acepromazine,experimental
CA4,DB00381,0.3870401140578033,Amlodipine,FDA approved
NOS3,DB07002,0.3868434459662277,4-({4-[(4-methoxypyridin-2-yl)amino]piperidin-1-yl}carbonyl)benzonitrile,experimental
DRD4,DB09207,0.38662192311831417,AS-8112,experimental
SLC6A3,DB04896,0.3864567292015263,Milnacipran,FDA approved
DRD4,DB01184,0.3853743564830144,Domperidone,FDA approved
NOS3,DB07011,0.38497276413699616,"(3S)-1-(1,3-BENZODIOXOL-5-YLMETHYL)-3-[4-(1H-IMIDAZOL-1-YL)PHENOXY]PIPERIDINE",experimental
SLC6A4,DB00696,0.3845570819965192,Ergotamine,FDA approved
NOS3,DB01234,0.3835917117817077,Dexamethasone,FDA approved
GABRG1,DB01544,0.3822461255802001,Flunitrazepam,FDA approved
HTR7,DB00714,0.3812620742982119,Apomorphine,FDA approved
SLC6A3,DB00289,0.3785435903991247,Atomoxetine,FDA approved
ESR2,DB08231,0.3783741428182611,Myristic acid,experimental
CHRNB4,DB09028,0.3764206519002461,Cytisine,experimental
DRD5,DB00353,0.3757171363451013,Methylergometrine,FDA approved
CACNA2D2,DB01115,0.3754452884196029,Nifedipine,FDA approved
HTR2B,DB00321,0.3750822924974235,Amitriptyline,FDA approved
NOS3,DB06916,0.3748872326974781,"N-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-1-[2-(1H-IMIDAZOL-1-YL)-6-METHYLPYRIMIDIN-4-YL]-D-PROLINAMIDE",experimental
SCN1B,DB00273,0.3746292274911247,Topiramate,FDA approved
OPRM1,DB00825,0.3732276361602721,Levomenthol,FDA approved
ADRB2,DB00555,0.3715656976697871,Lamotrigine,FDA approved
PGR,DB00139,0.3712490405105833,Succinic acid,FDA approved
CHRNB4,DB01273,0.3706647598009508,Varenicline,FDA approved
PTGS1,DB00210,0.3696185017198997,Adapalene,FDA approved
GABRR1,DB01956,0.3696152724908744,Taurine,FDA approved
PDE4D,DB00277,0.3684229033647134,Theophylline,FDA approved
HTR6,DB01200,0.36745945567564503,Bromocriptine,FDA approved
PDE5A,DB00824,0.3671065652989848,Enprofylline,FDA approved
PDE3A,DB00824,0.3650966107026529,Enprofylline,FDA approved
PDE4D,DB00824,0.3626767021024303,Enprofylline,FDA approved
HTR2B,DB00623,0.366897711466512,Fluphenazine,FDA approved
CSNK2A1,DB02010,0.36619647578492587,Staurosporine,experimental
ATP2C1,DB06637,0.3652914573787869,Dalfampridine,FDA approved
ATP5D,DB06637,0.34315594317792464,Dalfampridine,FDA approved
PPARA,DB09462,0.3648113661472489,Glycerin,FDA approved
CA3,DB00606,0.3640318558410789,Cyclothiazide,FDA approved
SLC6A4,DB13931,0.3636293301734175,Netarsudil,FDA approved
SCN1B,DB09085,0.3630277095000039,Tetracaine,FDA approved
SLC18A2,DB00191,0.3626501866568608,Phentermine,FDA approved
DRD5,DB00850,0.3619695374259261,Perphenazine,FDA approved
PTGS2,DB02379,0.3614650479597956,Beta-D-Glucose,experimental
RNASE1,DB02659,0.3614045889557694,Cholic Acid,FDA approved
SLC6A2,DB01191,0.3607307793715263,Dexfenfluramine,FDA approved
DRD4,DB09014,0.3601930512355497,Captodiame,experimental
SCN1B,DB09088,0.3588915223239442,Amylocaine,FDA approved
DRD5,DB00777,0.3579373044120457,Propiomazine,FDA approved
ADRB3,DB00489,0.3578481080482091,Sotalol,FDA approved
DRD5,DB00420,0.3578042577427257,Promazine,FDA approved
RARG,DB02746,0.3577506356646356,Phthalic Acid,experimental
SLC6A2,DB00215,0.35727438048771004,Citalopram,FDA approved
SLC6A4,DB00226,0.3571685252888854,Guanadrel,FDA approved
SCN1B,DB09342,0.35648495904493305,Propoxycaine,FDA approved
SLC6A2,DB09186,0.3564659923115143,Nisoxetine,experimental
SLC6A4,DB01170,0.3563439648602273,Guanethidine,FDA approved
SCN1B,DB09345,0.35626445912932153,Pramocaine,FDA approved
SCN1B,DB00564,0.3562400655610013,Carbamazepine,FDA approved
SLC6A4,DB04840,0.3557721793970202,Debrisoquine,FDA approved
CA3,DB00232,0.3557197446495365,Methyclothiazide,FDA approved
HTR2C,DB00751,0.35530333446772083,Epinastine,FDA approved
DRD1,DB00268,0.3546819185580857,Ropinirole,FDA approved
SLC6A4,DB00234,0.35457352850170776,Reboxetine,FDA approved
SLC6A4,DB09185,0.3544052583759161,Viloxazine,FDA approved
HTR2B,DB09195,0.3511571338572004,Lorpiprazole,FDA approved
SLC6A2,DB09195,0.34505098587930644,Lorpiprazole,FDA approved
CA4,DB00423,0.3511445904264309,Methocarbamol,FDA approved
PGR,DB00132,0.3507209293052647,alpha-Linolenic acid,FDA approved
SLC6A2,DB00574,0.3505949548508493,Fenfluramine,FDA approved
GABRA3,DB01346,0.3505908402968673,Quinidine barbiturate,FDA approved
GABRA5,DB01346,0.34693749369109583,Quinidine barbiturate,FDA approved
DRD5,DB01063,0.3501640204692105,Acetophenazine,FDA approved
PPARD,DB09213,0.3491100717200385,Dexibuprofen,FDA approved
CA4,DB00310,0.3478885142298774,Chlorthalidone,FDA approved
HTR7,DB00656,0.3460122191416373,Trazodone,FDA approved
PPARD,DB01050,0.3458560011278537,Ibuprofen,FDA approved
CA4,DB01031,0.3454746394450016,Ethinamate,FDA approved
HSD17B2,DB00255,0.3454016035516523,Diethylstilbestrol,FDA approved
RARG,DB01393,0.34536484520682703,Bezafibrate,FDA approved
CA4,DB09472,0.34452241640539283,Sodium sulfate,FDA approved
GABRR1,DB01068,0.3444978394462971,Clonazepam,FDA approved
SHBG,DB11219,0.3442528445873802,Enzacamene,FDA approved
SHBG,DB01428,0.3442058599747767,Oxybenzone,FDA approved
ADORA2A,DB01223,0.3437984838884494,Aminophylline,FDA approved
CA4,DB08157,0.34328384240283993,ETHYL 3-[4-(AMINOSULFONYL)PHENYL]PROPANOATE,experimental
CA4,DB08156,0.342851084475944,3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID,experimental
ESR1,DB02998,0.3424489727558131,Metribolone,experimental
CA4,DB08155,0.34242272939676743,N-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE,experimental
OPRD1,DB01227,0.3424026969506712,Levacetylmethadol,FDA approved
HTR2B,DB14185,0.3420572051381204,Aripiprazole lauroxil,FDA approved
HTR2B,DB00408,0.3417256417476033,Loxapine,FDA approved