,Term,Overlap,P.value,Adjusted.P.value,Combined.Score,Genes 1,Cytokine-cytokine receptor interaction,54/292,1.32E-11,3.61E-09,80.14668303,ACVRL1;IL21;CXCL9;CSF3R;CSF2;CSF1;TNF;CXCL16;TNFSF10;CCR8;CCR4;TNFRSF4;CCR3;CCR2;IL13RA1;IL10;IL1R2;TNFRSF1B;IL17RA;TNFRSF1A;TGFBR2;IFNG;IL23A;IL1B;LTA;XCL1;LTB;CSF1R;CXCR6;TNFRSF11A;IL2RG;IL1RL1;CCL4;IL21R;CCL3;CCL1;CCL17;CCL24;XCR1;CCL22;TGFB1;CD70;IL10RA;TNFRSF9;IL2;CD40LG;IL5;FASL;IL2RB;TNFSF9;LTBR;IL7R;IL18R1;IL17A 2,T cell receptor signaling pathway,27/101,4.46E-10,6.09E-08,109.5023318,ITK;CSF2;PIK3CD;CD3G;TNF;RASGRP1;PPP3CA;GRAP2;PAK6;FYN;MAPK3;IL10;JUN;NFATC2;CD8B1;NFATC1;FOS;MAPK14;IL2;IL5;CD40LG;IFNG;CD8A;CD28;LCP2;PDCD1;CARD11 3,Inflammatory bowel disease (IBD),19/59,5.82E-09,5.30E-07,125.0242411,IL21;IL10;JUN;TGFB1;RORA;NFATC1;IL2RG;TNF;FOXP3;IL2;IL5;IFNG;IL23A;IL1B;TBX21;IL21R;IL18R1;TLR2;IL17A 4,Th17 cell differentiation,25/102,1.35E-08,9.24E-07,81.85940757,IL21;RORA;CD3G;GATA3;IL2RG;PPP3CA;TBX21;IL21R;MAPK3;JUN;TGFB1;NFATC2;NFATC1;FOS;MAPK14;FOXP3;IL2;RUNX1;TGFBR2;IFNG;IL23A;IL1B;IL2RB;RARA;IL17A 5,Osteoclast differentiation,28/128,2.74E-08,1.50E-06,67.91081264,CSF1R;SPI1;CSF1;FHL2;PIK3CD;TNFRSF11A;TNF;PPP3CA;FYN;JUNB;MAPK3;JUN;TGFB1;JUND;NFATC2;NFATC1;FOS;MAPK14;TNFRSF1A;TGFBR2;FCGR3;IFNG;FCGR4;IL1B;FOSB;LCP2;PPARG;SQSTM1 6,Human T-cell leukemia virus 1 infection,41/245,7.25E-08,3.00E-06,46.21845176,RB1;NRP1;CDKN1A;H2-T22;SPI1;CSF2;H2-Q6;ITGB2;ADCY4;PIK3CD;CD3G;H2-Q2;ITGAL;IL2RG;ADCY7;TNF;PPP3CA;ZFP36;CREB3L2;E2F2;MAPK3;EGR1;EGR2;JUN;CDKN2C;TGFB1;H2-T10;IL1R2;NFATC2;NFATC1;FOS;IL2;TNFRSF1A;TGFBR2;IL2RB;LTA;LTBR;TLN1;H2-D1;H2-Q10;BCL2L1 7,Human cytomegalovirus infection,42/255,8.00E-08,3.00E-06,45.0877803,RB1;PTGER4;CDKN1A;H2-T22;SRC;H2-Q6;ADCY4;ITPR1;PIK3CD;H2-Q2;ADCY7;TNF;GNAI2;GNA13;PPP3CA;AKAP13;GNG2;CREB3L2;CCL4;RAC2;CCL3;E2F2;PTK2B;ITGAV;CCR3;MAPK3;PRKCG;ARHGEF12;H2-T10;IL10RA;NFATC2;NFATC1;MAPK14;TNFRSF1A;FASL;IL1B;GNAQ;TRAF5;GNB4;GNB5;H2-D1;H2-Q10 8,Pathways in cancer,70/535,9.41E-08,3.00E-06,34.34268711,RB1;CDKN1A;SPI1;CSF3R;ITGA2B;PIK3CD;LAMC1;BBC3;CASP7;EDNRB;CDH1;RASSF5;RAC2;ITGAV;IL13RA1;PRKCG;EDN1;ARHGEF12;ITGA3;DAPK2;F2R;FOS;MMP9;RUNX1;TGFBR2;AR;COL4A2;IFNG;IL23A;TRAF5;RARA;PPARG;PTGER4;CAMK2B;CSF1R;LAMA5;RALA;EPAS1;MGST3;ADCY4;GSTT3;GSTT1;IL2RG;ADCY7;RASGRP1;DLL1;GNAI2;GNA13;GNG2;WNT11;CTNNA1;E2F2;PMAIP1;RALGDS;WNT3;MAPK3;WNT10B;ARNT2;JUN;TGFB1;JUP;IL2;IL5;FASL;GNAQ;IL2RB;GNB4;GNB5;IL7R;BCL2L1 9,C-type lectin receptor signaling pathway,25/112,9.91E-08,3.00E-06,64.4573044,CLEC4N;SRC;ITPR1;PIK3CD;LSP1;TNF;PPP3CA;CASP1;CCL17;MAPK3;IL10;PLK3;EGR2;JUN;EGR3;ARHGEF12;CCL22;NFATC2;NFATC1;MAPK14;IL2;IL23A;IL1B;MAPKAPK2;CLEC4E 10,Allograft rejection,18/63,1.17E-07,3.05E-06,88.54288822,CD86;IL10;H2-T22;H2-T10;CD80;H2-Q6;PRF1;GZMB;H2-Q2;TNF;IL2;IL5;CD40LG;IFNG;FASL;CD28;H2-D1;H2-Q10 11,Cell adhesion molecules (CAMs),32/170,1.25E-07,3.05E-06,51.38744017,CD86;H2-T22;ITGAM;SELPLG;SDC4;CD80;H2-Q6;ITGB2;H2-Q2;F11R;ITGAL;SPN;CDH5;ALCAM;CDH1;ITGAV;ITGB7;TIGIT;JAM2;H2-T10;CD8B1;PDCD1LG2;L1CAM;CD40LG;CD6;CD8A;CD28;CD226;ESAM;PDCD1;H2-D1;H2-Q10 12,Rheumatoid arthritis,21/84,1.34E-07,3.05E-06,73.24746485,CD86;JUN;CSF2;TGFB1;CSF1;CD80;ITGB2;FOS;TNFRSF11A;ITGAL;TNF;IFNG;IL23A;IL1B;CCL3;CD28;LTB;TEK;TLR2;ATP6V0A1;IL17A 13,"Parathyroid hormone synthesis, secretion and action",24/107,1.61E-07,3.39E-06,62.86755479,PRKCG;EGR1;CDKN1A;JUND;VDR;PDE4C;ITPR1;ADCY4;GATA3;FOS;ADCY7;RUNX2;PLD2;GNAI2;NR4A2;GNA13;AKAP13;MAFB;MMP13;GNAQ;CREB3L2;MMP17;HBEGF;MAPK3 14,Natural killer cell mediated cytotoxicity,25/118,2.88E-07,5.62E-06,56.28476474,CSF2;ITGB2;PRF1;PIK3CD;ITGAL;TNF;PPP3CA;KLRK1;TNFSF10;RAC2;PTK2B;FYN;KLRC1;MAPK3;PRKCG;KLRC2;NFATC2;GZMB;NFATC1;FASL;IFNG;FCGR4;LCP2;ULBP1;H2-D1 15,Chagas disease (American trypanosomiasis),23/103,3.16E-07,5.76E-06,59.77881381,IL10;JUN;TGFB1;ACE;PIK3CD;CD3G;FOS;CFLAR;MAPK14;TNF;IL2;TNFRSF1A;TGFBR2;GNAI2;GNA15;FASL;IFNG;PPP2R2C;GNAQ;IL1B;CCL3;TLR2;MAPK3 16,Kaposi sarcoma-associated herpesvirus infection,36/216,4.94E-07,8.43E-06,40.52224413,RB1;CD86;CDKN1A;H2-T22;CSF2;SRC;H2-Q6;ITPR1;PIK3CD;H2-Q2;PIK3R6;PIK3CG;PREX1;PPP3CA;ZFP36;GNG2;CCR8;E2F2;CCR4;CCR3;MAPK3;GABARAPL1;JUN;H2-T10;NFATC2;NFATC1;FOS;ATG14;MAPK14;TNFRSF1A;CD200R1;MAPKAPK2;GNB4;GNB5;H2-D1;H2-Q10 17,Transcriptional misregulation in cancer,32/183,7.08E-07,1.14E-05,41.81318216,CD86;CSF1R;CDKN1A;CSF2;SPI1;ITGAM;HPGD;TSPAN7;NFKBIZ;NSD2;ITGB7;BCL2A1A;ARNT2;CDKN2C;JUP;IL1R2;GZMB;MMP9;RUNX2;DUSP6;MLF1;RUNX1;TGFBR2;SPINT1;DDIT3;ID2;IL2RB;REL;RARA;PPARG;CDK14;BCL2L1 18,Graft-versus-host disease,17/64,8.21E-07,1.25E-05,70.22317129,CD86;H2-T22;H2-T10;CD80;H2-Q6;PRF1;GZMB;H2-Q2;TNF;IL2;IFNG;FASL;IL1B;CD28;KLRC1;H2-D1;H2-Q10 19,Fluid shear stress and atherosclerosis,27/143,1.11E-06,1.59E-05,44.38574142,SDC4;SRC;MGST3;ITGA2B;GSTT3;PIK3CD;GSTT1;TNF;PRKCZ;CDH5;THBD;GPC1;RAC2;ITGAV;JUN;EDN1;DUSP1;IL1R2;CAV1;FOS;MAPK14;MMP9;TNFRSF1A;IFNG;IL1B;ARHGEF2;SQSTM1 20,Chemokine signaling pathway,33/197,1.30E-06,1.77E-05,38.00205951,ITK;CXCL9;SRC;ADCY4;PIK3CD;CXCR6;PRKCZ;ADCY7;PIK3R6;PIK3CG;GNAI2;CXCL16;PREX1;GNG2;CCL4;RAC2;CCL3;CCR8;PTK2B;CCL1;CCR4;CCL17;CCR3;CCR2;MAPK3;CCL24;XCR1;CCL22;FGR;TIAM1;GNB4;XCL1;GNB5 21,Steroid biosynthesis,19-Sep,1.49E-06,1.94E-05,166.6511148,SQLE;SOAT1;SOAT2;SC5D;DHCR24;DHCR7;LIPA;CYP51;FDFT1 22,Amoebiasis,22/106,2.11E-06,2.62E-05,47.50498703,PRKCG;IL10;LAMA5;CSF2;TGFB1;ITGAM;IL1R2;ITGB2;PIK3CD;ACTN4;LAMC1;TNF;GNA15;SERPINB1B;COL3A1;COL4A2;SERPINB6A;IFNG;GNAQ;IL1B;VCL;TLR2 23,Type I diabetes mellitus,17/69,2.57E-06,3.05E-05,58.29169808,CD86;H2-T22;H2-T10;CD80;H2-Q6;PRF1;GZMB;H2-Q2;TNF;IL2;IFNG;FASL;IL1B;LTA;CD28;H2-D1;H2-Q10 24,Platelet activation,24/125,3.17E-06,3.61E-05,41.77961567,PTGIR;ARHGEF12;SRC;ITGA2B;F2R;ITPR1;ADCY4;PIK3CD;MAPK14;PRKCZ;RASGRP1;ADCY7;PIK3R6;PIK3CG;GNAI2;VAMP8;GNA13;COL3A1;STIM1;GNAQ;LCP2;FYN;TLN1;MAPK3 25,Tuberculosis,30/178,3.42E-06,3.73E-05,35.50334118,CAMK2B;ITGAM;SRC;ITGB2;LSP1;TNF;EEA1;PPP3CA;IRAK2;MRC1;ITGAX;CTSD;ATP6V0A1;MAPK3;IL10;PLK3;TGFB1;ARHGEF12;VDR;SPHK1;IL10RA;MAPK14;TNFRSF1A;FCGR3;IFNG;FCGR4;IL23A;IL1B;CLEC4E;TLR2 26,TNF signaling pathway,22/110,4.02E-06,4.22E-05,43.0992837,JUN;EDN1;CSF2;CSF1;MLKL;TNFAIP3;PIK3CD;FOS;CFLAR;TNFRSF1B;MAPK14;TNF;MMP9;TNFRSF1A;CASP7;IL1B;CREB3L2;TRAF5;LTA;JUNB;IL18R1;MAPK3 27,Rap1 signaling pathway,33/209,4.91E-06,4.97E-05,31.91572454,CSF1R;RALA;ITGAM;CSF1;SRC;ITGA2B;ITGB2;ADCY4;PIK3CD;SIPA1L2;ITGAL;PRKCZ;ADCY7;THBS1;GNAI2;CDH1;RASSF5;RAC2;RALGDS;MAPK3;PRKCG;F2R;MAPK14;TIAM1;ADORA2A;ADORA2B;GNAQ;RAPGEF2;PRKD2;LCP2;TEK;TLN1;EPHA2 28,Hematopoietic cell lineage,19/94,1.53E-05,0.000149393,38.91245191,CSF1R;CSF3R;CSF2;ITGAM;CSF1;ITGA3;IL1R2;ITGA2B;ITGA1;CD8B1;CD3G;TNF;IL5;CD8A;IL1B;CD38;CD36;IL7R;CD44 29,Malaria,13/49,1.62E-05,0.000152964,55.04297411,IL10;TGFB1;LRP1;ITGB2;HBA-A1;ITGAL;TNF;THBS1;CD40LG;IFNG;IL1B;CD36;TLR2 30,Relaxin signaling pathway,23/131,2.33E-05,0.000212372,31.50810811,JUN;EDN1;TGFB1;SRC;ADCY4;PIK3CD;FOS;MAPK14;PRKCZ;MMP9;ADCY7;TGFBR2;GNAI2;GNA15;COL3A1;EDNRB;MMP13;GNG2;COL4A2;CREB3L2;GNB4;GNB5;MAPK3 31,Apoptosis,24/141,2.66E-05,0.00023446,29.98197341,JUN;PARP4;PRF1;ITPR1;EIF2AK3;PIK3CD;GZMB;FOS;CFLAR;PTPN13;TNF;BBC3;TNFRSF1A;CASP7;FASL;DDIT3;LMNA;CAPN2;TNFSF10;PMAIP1;BCL2A1A;CTSD;BCL2L1;MAPK3 32,IL-17 signaling pathway,18/91,3.46E-05,0.000295019,35.07113366,JUN;CSF2;JUND;TNFAIP3;FOS;MAPK14;TNF;MMP9;IL17RA;MMP13;IL5;IFNG;IL1B;TRAF5;FOSB;CCL17;MAPK3;IL17A 33,Autoimmune thyroid disease,16/78,5.86E-05,0.000484573,34.79090194,CD86;IL10;H2-T22;H2-T10;CD80;H2-Q6;PRF1;GZMB;H2-Q2;IL2;IL5;CD40LG;FASL;CD28;H2-D1;H2-Q10 34,Th1 and Th2 cell differentiation,17/87,6.65E-05,0.000534092,32.32368167,JUN;NFATC2;CD3G;NFATC1;FOS;GATA3;RBPJ;IL2RG;MAPK14;DLL1;IL2;PPP3CA;IL5;IFNG;TBX21;IL2RB;MAPK3 35,Sphingolipid signaling pathway,21/124,8.94E-05,0.000697583,26.33289145,PRKCG;CERS6;SGMS1;SPHK1;PPP2R5B;PIK3CD;MAPK14;TNF;PRKCZ;PLD2;TNFRSF1A;GNAI2;GNA13;PPP2R2C;GNAQ;SMPD1;RAC2;FYN;CTSD;S1PR4;MAPK3 36,Leishmaniasis,14/67,0.000135757,0.001029493,32.50715573,IL10;JUN;ITGAM;TGFB1;ITGB2;FOS;MAPK14;TNF;FCGR3;IFNG;FCGR4;IL1B;TLR2;MAPK3 37,Pertussis,15/76,0.000156145,0.001152094,29.79519969,IL10;JUN;ITGAM;TICAM2;ITGB2;NOD1;FOS;MAPK14;TNF;GNAI2;CASP7;IL23A;IL1B;CASP1;MAPK3 38,NF-kappa B signaling pathway,18/102,0.000162909,0.001170376,25.86449579,CARD10;TICAM2;TNFAIP3;TNFRSF11A;CFLAR;TNF;TNFRSF1A;CD40LG;IL1B;TRAF5;CCL4;LTA;ERC1;LTB;LTBR;BCL2A1A;CARD11;BCL2L1 39,Human immunodeficiency virus 1 infection,32/238,0.000169267,0.001184869,18.74029693,H2-T22;H2-Q6;ITPR1;PIK3CD;CD3G;H2-Q2;TNF;GNAI2;PPP3CA;GNG2;RAC2;PAK6;PTK2B;MAPK3;PRKCG;JUN;H2-T10;NFATC2;NFATC1;FOS;TNFRSF1B;MAPK14;TNFRSF1A;FASL;GNAQ;TRAF5;GNB4;GNB5;H2-D1;H2-Q10;TLR2;BCL2L1 40,Viral myocarditis,16/87,0.000226335,0.001544738,26.15413049,CD86;H2-T22;H2-T10;CD80;H2-Q6;CAV1;ITGB2;PRF1;H2-Q2;ITGAL;CD40LG;RAC2;CD28;FYN;H2-D1;H2-Q10 41,Leukocyte transendothelial migration,19/115,0.00026448,0.00176105,22.56382622,PRKCG;ITK;ITGAM;ITGB2;PIK3CD;ACTN4;F11R;ITGAL;MAPK14;MMP9;GNAI2;CDH5;RASSF5;RAC2;CTNNA1;PTK2B;ESAM;VCL;JAM2 42,Hepatitis B,24/163,0.000275723,0.001792198,19.61290345,RB1;PRKCG;EGR2;JUN;CDKN1A;TICAM2;TGFB1;EGR3;SRC;NFATC2;PIK3CD;NFATC1;FOS;MAPK14;TNF;MMP9;TGFBR2;IFIH1;FASL;CREB3L2;E2F2;PTK2B;TLR2;MAPK3 43,Bladder cancer,Oct-41,0.000325833,0.00206866,35.73065725,RB1;CDKN1A;SRC;CDH1;DAPK2;E2F2;THBS1;MMP9;MAPK3;HBEGF 44,Toxoplasmosis,18/108,0.000340069,0.002109975,22.09619525,IL10;LAMA5;TGFB1;IL10RA;LAMC1;MAPK14;TNF;PIK3R6;PIK3CG;TNFRSF1A;GNAI2;CD40LG;IFNG;LDLR;BCL2L1;TLR2;MAPK3;HSPA1A 45,Regulation of actin cytoskeleton,29/217,0.000370335,0.002246696,16.90998613,CYFIP1;NCKAP1;ITGAM;SRC;ITGA2B;ITGB2;PIK3CD;IQGAP1;ITGAE;IQGAP2;ITGAL;GNA13;RAC2;ITGAX;PAK6;ITGAV;ITGB7;MAPK3;ARHGEF12;ITGA3;F2R;ITGA1;ACTN4;BAIAP2;SSH1;TIAM1;ABI2;MYH9;VCL 46,MAPK signaling pathway,36/294,0.000441913,0.002622658,14.97627949,CSF1R;CSF1;AREG;TNF;RASGRP1;PPP3CA;RPS6KA2;RAC2;FLNB;MAPK3;PRKCG;DUSP4;JUN;DUSP2;JUND;TGFB1;DUSP1;NFATC1;FOS;DUSP8;MAPK14;DUSP6;TNFRSF1A;TGFBR2;NR4A1;CACNB3;FASL;MAPKAPK3;DDIT3;IL1B;MAPKAPK2;RAPGEF2;TEK;PTPN5;EPHA2;HSPA1A 47,Intestinal immune network for IgA production,Oct-43,0.000492157,0.002858697,31.83768191,CD86;IL10;TGFB1;IL5;CD40LG;CD80;CD28;ITGB7;LTBR;IL2 48,Proteoglycans in cancer,27/203,0.000624782,0.00355345,15.69065734,CAMK2B;CDKN1A;SDC4;SRC;ITPR1;PIK3CD;IQGAP1;TNF;THBS1;WNT11;GPC1;FLNB;ITGAV;WNT3;MAPK3;PRKCG;WNT10B;TGFB1;ARHGEF12;CAV1;MAPK14;MMP9;TIAM1;FASL;CD44;TLR2;HBEGF 49,Adherens junction,13/72,0.001020496,0.00568562,20.9506858,SRC;PTPRJ;ACTN4;IQGAP1;BAIAP2;TGFBR2;TJP1;CDH1;RAC2;CTNNA1;FYN;VCL;MAPK3 50,Axon guidance,24/180,0.001176458,0.006423462,14.36887227,CAMK2B;NRP1;SEMA4A;SEMA6A;ARHGEF12;SEMA4D;SRC;SEMA6D;SEMA4C;NFATC2;PIK3CD;L1CAM;PRKCZ;SSH1;RND1;GNAI2;PPP3CA;RGS3;DPYSL2;RAC2;PAK6;FYN;EPHA2;MAPK3 51,AGE-RAGE signaling pathway in diabetic complications,16/101,0.001248295,0.006682048,17.3889869,EGR1;JUN;EDN1;TGFB1;PIK3CD;NFATC1;MAPK14;TNF;PRKCZ;TGFBR2;THBD;COL3A1;COL4A2;IL1B;PLCD1;MAPK3 52,ECM-receptor interaction,14/83,0.001328035,0.006972186,18.5583448,LAMA5;SDC4;ITGA3;ITGA2B;ITGA1;LAMC1;NPNT;THBS1;SV2C;COL4A2;ITGAV;ITGB7;CD36;CD44 53,Cholinergic synapse,17/113,0.001601961,0.008150906,15.75083599,PRKCG;CAMK2B;ITPR1;ADCY4;PIK3CD;FOS;ADCY7;PIK3R6;PIK3CG;GNAI2;GNG2;GNAQ;CREB3L2;GNB4;FYN;GNB5;MAPK3 54,VEGF signaling pathway,Nov-58,0.001612267,0.008150906,20.7585222,PRKCG;PPP3CA;MAPKAPK3;SRC;SPHK1;MAPKAPK2;RAC2;PIK3CD;NFATC2;MAPK14;MAPK3 55,Cellular senescence,24/185,0.001717521,0.008525152,13.13809075,RB1;LIN54;H2-T22;CDKN1A;TGFB1;H2-T10;H2-Q6;ITPR1;NFATC2;PIK3CD;NFATC1;H2-Q2;MAPK14;TGFBR2;RBL2;PPP3CA;RASSF5;MAPKAPK2;CAPN2;E2F2;SQSTM1;H2-D1;H2-Q10;MAPK3 56,Viral carcinogenesis,28/229,0.001849621,0.009016904,12.1447057,RB1;CDKN1A;H2-T22;SRC;H2-Q6;PIK3CD;H2-Q2;RBPJ;CREB3L2;CCR8;PMAIP1;CCR4;CCR3;MAPK3;EGR2;JUN;EGR3;H2-T10;ACTN4;RBL2;MAPKAPK2;TRAF5;REL;LTBR;HIST1H4D;H2-D1;H2-Q10;HIST1H2BC 57,Salmonella infection,13/78,0.002175147,0.010417811,16.92171155,JUN;CSF2;FOS;KLC1;MAPK14;TJP1;IFNG;IL1B;CCL4;CASP1;CCL3;FLNB;MAPK3 58,Adrenergic signaling in cardiomyocytes,20/148,0.002475911,0.011653856,12.96434289,CAMK2B;TPM4;TPM1;PPP2R5B;ADCY4;ATP2B4;ADRB1;ATP2B1;MAPK14;ADCY7;PIK3R6;PIK3CG;GNAI2;CACNB3;PPP2R2C;GNAQ;CREB3L2;SCN7A;SCN1B;MAPK3 59,Phospholipase D signaling pathway,20/149,0.002681704,0.012408564,12.69200745,RALA;SPHK1;F2R;ADCY4;PIK3CD;ADCY7;PIK3R6;PIK3CG;PLD2;AGPAT4;GNA13;CYTH2;CYTH4;PTK2B;FYN;PLPP2;RALGDS;PLPP1;ARF6;MAPK3 60,Toll-like receptor signaling pathway,15/99,0.002737738,0.012456707,14.54850476,CD86;JUN;CXCL9;TICAM2;CD80;PIK3CD;FOS;MAPK14;TNF;IL1B;CCL4;CCL3;IRF5;TLR2;MAPK3 61,Endocytosis,31/269,0.002785798,0.012467587,10.61916698,H2-T22;SRC;H2-Q6;CLTC;AGAP1;H2-Q2;IL2RG;PRKCZ;PLD2;EEA1;CYTH2;CYTH4;LDLR;RAB11FIP4;H2-T10;CAV1;VPS37B;ARFGAP3;IGF2R;TGFBR2;EPN2;RUFY1;EHD3;ACAP2;RAB31;BIN1;IL2RB;H2-D1;H2-Q10;ARF6;HSPA1A 62,Antigen processing and presentation,14/90,0.002916796,0.012639451,14.84215109,H2-T22;H2-T10;KLRC2;KLRC3;H2-Q6;CD8B1;H2-Q2;TNF;IFNG;CD8A;KLRC1;H2-D1;H2-Q10;HSPA1A 63,Dilated cardiomyopathy (DCM),14/90,0.002916796,0.012639451,14.84215109,TGFB1;TPM4;ITGA3;ITGA2B;ITGA1;TPM1;ADCY4;ADRB1;TNF;ADCY7;CACNB3;LMNA;ITGAV;ITGB7 64,Oxytocin signaling pathway,20/154,0.003938454,0.016799966,11.42227441,PRKCG;CAMK2B;JUN;CDKN1A;SRC;ITPR1;ADCY4;NFATC2;NFATC1;FOS;ADCY7;PIK3R6;PIK3CG;GNAI2;PPP3CA;RGS2;CACNB3;GNAQ;CD38;MAPK3 65,PI3K-Akt signaling pathway,38/357,0.004069396,0.017046508,9.094146921,CSF1R;LAMA5;CDKN1A;PHLPP1;CSF3R;CSF1;ITGA2B;PIK3CD;LAMC1;IL2RG;AREG;THBS1;PIK3R6;PIK3CG;GNG2;CREB3L2;ITGAV;ITGB7;MAPK3;ITGA3;F2R;ITGA1;PPP2R5B;IL2;RBL2;NR4A1;FASL;COL4A2;PPP2R2C;IL2RB;GNB4;GNB5;TEK;IL7R;PIK3AP1;EPHA2;TLR2;BCL2L1 66,African trypanosomiasis,Aug-39,0.004121134,0.017046508,19.52182183,PRKCG;IL10;FASL;IFNG;IL1B;GNAQ;HBA-A1;TNF 67,Lysosome,17/124,0.004335462,0.017665391,11.93863536,SCARB2;ABCA2;SLC11A1;HEXB;CLTC;LAPTM5;ABCB9;LIPA;LITAF;IGF2R;GM2A;NPC1;SMPD1;IDS;ARSG;CTSD;ATP6V0A1 68,Focal adhesion,24/199,0.004478967,0.017981736,10.25960347,PRKCG;LAMA5;JUN;ITGA3;SRC;CAV1;ITGA2B;ITGA1;PIK3CD;ACTN4;LAMC1;THBS1;COL4A2;RAC2;ZYX;CAPN2;PAK6;FLNB;ITGAV;ITGB7;FYN;TLN1;VCL;MAPK3 69,Calcium signaling pathway,23/189,0.004764596,0.018851228,10.24402814,PRKCG;CAMK2B;SPHK1;F2R;ITPR1;ATP2A3;ADCY4;ATP2B4;ADRB1;ATP2B1;ADCY7;PPP3CA;CYSLTR1;GNA15;EDNRB;STIM1;ADORA2A;STIM2;ADORA2B;GNAQ;CD38;PTK2B;PLCD1 70,Hypertrophic cardiomyopathy (HCM),13/86,0.005199431,0.020277779,12.91994768,EDN1;TGFB1;ACE;TPM4;ITGA3;ITGA2B;ITGA1;TPM1;TNF;CACNB3;LMNA;ITGAV;ITGB7 71,Colorectal cancer,13/88,0.006329505,0.024337391,12.10384265,CDKN1A;RALA;JUN;TGFB1;PIK3CD;FOS;AREG;BBC3;TGFBR2;RAC2;PMAIP1;RALGDS;MAPK3 72,Acute myeloid leukemia,Nov-69,0.006531986,0.024767113,13.15372525,CSF1R;CSF2;SPI1;ITGAM;JUP;RARA;PIK3CD;BCL2A1A;DUSP6;RUNX1;MAPK3 73,Prion diseases,Jul-34,0.006993093,0.026152251,17.71441847,EGR1;PRNP;IL1B;FYN;LAMC1;MAPK3;HSPA1A 74,GnRH signaling pathway,13/90,0.007646645,0.028209919,11.34799298,CAMK2B;EGR1;JUN;SRC;ADCY4;ITPR1;MAPK14;ADCY7;PLD2;GNAQ;PTK2B;HBEGF;MAPK3 75,B cell receptor signaling pathway,Nov-72,0.008996873,0.032748616,11.70902002,PPP3CA;IFITM1;JUN;RAC2;PIK3CD;NFATC2;NFATC1;FOS;PIK3AP1;CARD11;MAPK3 76,Estrogen signaling pathway,17/134,0.009393999,0.033744232,9.361528966,NCOA2;JUN;SRC;ITPR1;ADCY4;PIK3CD;FOS;MMP9;ADCY7;GNAI2;GNAQ;CREB3L2;RARA;CTSD;HBEGF;MAPK3;HSPA1A 77,Mitophagy,Oct-63,0.009573549,0.033942584,12.08596001,GABARAPL1;JUN;SRC;NBR1;TFEB;TAX1BP1;EIF2AK3;SQSTM1;OPTN;BCL2L1 78,Pancreatic cancer,Nov-75,0.012124892,0.042437121,10.45159577,RB1;CDKN1A;RALA;TGFB1;RAC2;PIK3CD;E2F2;RALGDS;TGFBR2;MAPK3;BCL2L1 79,JAK-STAT signaling pathway,19/164,0.015846657,0.054663555,7.496557088,IL21;IL10;CDKN1A;CSF3R;CSF2;CISH;IL10RA;PIK3CD;IL2RG;IL2;SOCS2;IL5;IFNG;IL23A;IL2RB;IL21R;IL7R;IL13RA1;BCL2L1 80,Salivary secretion,Nov-78,0.016018624,0.054663555,9.351994507,PRKCG;BST1;GNAQ;ADCY4;ITPR1;ATP2B4;CD38;ADRB1;ATP2B1;KCNN4;ADCY7 81,Circadian entrainment,13/99,0.016444038,0.055266997,8.559911583,PRKCG;CAMK2B;ITPR1;ADCY4;FOS;ADCY7;GNAI2;GNG2;RASD1;GNAQ;GNB4;GNB5;MAPK3 82,Cholesterol metabolism,Aug-49,0.016600344,0.055266997,11.00958252,NPC1;SOAT1;LRP1;SOAT2;CD36;ANGPTL4;LIPA;LDLR 83,FoxO signaling pathway,16/132,0.017266644,0.056792695,7.722554378,IL10;PLK3;GABARAPL1;CDKN1A;TGFB1;PLK2;PIK3CD;MAPK14;TGFBR2;RBL2;FASL;CCNG2;TNFSF10;IL7R;S1PR4;MAPK3 84,Melanogenesis,13/100,0.017764992,0.057736223,8.301914721,PRKCG;CAMK2B;WNT10B;EDN1;ADCY4;ADCY7;GNAI2;EDNRB;WNT11;GNAQ;CREB3L2;WNT3;MAPK3 85,Measles,17/144,0.018327083,0.058862278,7.385588589,JUN;EIF2AK3;TNFAIP3;PIK3CD;CD3G;FOS;IL2RG;IL2;BBC3;IFIH1;FASL;IL1B;IL2RB;CD28;BCL2L1;TLR2;HSPA1A 86,Aldosterone synthesis and secretion,13/102,0.020645371,0.06553705,7.811965417,PRKCG;CAMK2B;ITPR1;ADCY4;ATP2B4;ATP2B1;ADCY7;NR4A2;NR4A1;GNAQ;CREB3L2;PRKD2;LDLR 87,p53 signaling pathway,Oct-71,0.021259053,0.066709442,8.69509512,CDKN1A;CD82;PERP;CCNG2;PMAIP1;SFN;GTSE1;THBS1;BBC3;BCL2L1 88,Small cell lung cancer,Dec-92,0.021681342,0.067261436,7.919022124,RB1;LAMA5;CDKN1A;COL4A2;ITGA3;ITGA2B;TRAF5;PIK3CD;E2F2;ITGAV;LAMC1;BCL2L1 89,Cushing syndrome,18/159,0.022859461,0.07011947,6.654311848,RB1;CAMK2B;WNT10B;CDKN1A;CDKN2C;ITPR1;ADCY4;ADCY7;GNAI2;NR4A1;RASD1;WNT11;GNAQ;CREB3L2;E2F2;LDLR;WNT3;MAPK3 90,Amyotrophic lateral sclerosis (ALS),Aug-52,0.023179222,0.070310306,9.421760077,PPP3CA;CASP1;TNFRSF1B;MAPK14;TNF;TNFRSF1A;PRPH;BCL2L1 91,cGMP-PKG signaling pathway,19/172,0.024860432,0.074581296,6.329951285,ITPR1;ATP2A3;ADCY4;ATP2B4;NFATC2;ADRB1;NFATC1;ATP2B1;ADCY7;PIK3R6;PIK3CG;GNAI2;GNA13;PPP3CA;RGS2;EDNRB;GNAQ;CREB3L2;MAPK3 92,Apelin signaling pathway,16/138,0.025190645,0.074750502,6.657341351,EGR1;GABARAPL1;SPHK1;ITPR1;ADCY4;ADCY7;PIK3R6;PIK3CG;GNAI2;GNA13;GNG2;CDH1;GNAQ;GNB4;GNB5;MAPK3 93,Mineral absorption,Jul-44,0.027686451,0.08127313,9.337585354,VDR;FTH1;SLC30A1;MT2;MT1;ATP2B1;TRPM6 94,Necroptosis,19/176,0.030619169,0.087960203,5.819538778,CAMK2B;TICAM2;PARP4;MLKL;TNFAIP3;PYGL;CFLAR;TNF;TNFRSF1A;FASL;IFNG;FTH1;SMPD1;IL1B;TRAF5;CAPN2;TNFSF10;CASP1;SQSTM1 95,Gap junction,Nov-86,0.030913421,0.087960203,7.022798543,PRKCG;TJP1;SRC;GNAQ;ADCY4;ITPR1;ADRB1;ADCY7;TUBB4A;GNAI2;MAPK3 96,Glycosphingolipid biosynthesis,Jul-45,0.03093106,0.087960203,8.810484811,B4GALT1;FUT7;HEXB;A3GALT2;GGTA1;FUT4;B4GALT4 97,Human papillomavirus infection,34/360,0.032542084,0.091357149,4.937885046,RB1;PTGER4;LAMA5;CDKN1A;H2-T22;H2-Q6;ITGA2B;PIK3CD;H2-Q2;LAMC1;RBPJ;PRKCZ;TNF;THBS1;LFNG;WNT11;CREB3L2;ITGAV;ITGB7;WNT3;ATP6V0A1;MAPK3;WNT10B;H2-T10;ITGA3;ITGA1;PPP2R5B;TNFRSF1A;RBL2;FASL;COL4A2;PPP2R2C;H2-D1;H2-Q10 98,Nicotinate and nicotinamide metabolism,Jun-36,0.032794874,0.091357149,9.40174089,BST1;NT5E;NMRK1;QPRT;ENPP1;CD38 99,Fc gamma R-mediated phagocytosis,Nov-87,0.033300221,0.091827882,6.781767193,PRKCG;MYO10;BIN1;SPHK1;RAC2;PIK3CD;PLPP2;PLPP1;ARF6;PLD2;MAPK3 100,Tight junction,18/167,0.035120143,0.095877992,5.578969056,JUN;SRC;ACTN4;F11R;PRKCZ;RUNX1;RAP2C;TJP1;TIAM1;MARVELD2;PPP2R2C;RAPGEF2;MYH9;AMOTL2;ARHGEF2;JAM2;TJP3;TJP2 101,Choline metabolism in cancer,Dec-99,0.035960257,0.097199506,6.317832782,PRKCG;SLC22A4;JUN;PCYT1A;RAC2;PIK3CD;FOS;PLPP2;RALGDS;PLPP1;PLD2;MAPK3 102,Phagosome,19/180,0.037320049,0.099886015,5.351633512,H2-T22;ITGAM;H2-T10;H2-Q6;ITGB2;H2-Q2;THBS1;TUBB4A;EEA1;FCGR3;FCGR4;MRC1;OLR1;ITGAV;CD36;H2-D1;H2-Q10;ATP6V0A1;TLR2 103,Fc epsilon RI signaling pathway,Sep-68,0.039903984,0.105764929,6.763594162,CSF2;IL5;RAC2;PIK3CD;LCP2;FYN;MAPK14;TNF;MAPK3 104,Dopaminergic synapse,15/135,0.040895732,0.107351298,5.506568846,PRKCG;CAMK2B;ITPR1;PPP2R5B;FOS;MAPK14;ARNTL;GNAI2;PPP3CA;GNG2;PPP2R2C;GNAQ;CREB3L2;GNB4;GNB5 105,Legionellosis,Aug-58,0.041425725,0.107706885,7.010038789,CASP7;ITGAM;IL1B;ITGB2;CASP1;TNF;TLR2;HSPA1A 106,Sphingolipid metabolism,Jul-48,0.042161529,0.108585823,7.436956543,NEU4;CERS6;SGMS1;SMPD1;SPHK1;PLPP2;PLPP1 107,Ras signaling pathway,23/233,0.046043322,0.117475018,4.650974327,PRKCG;CSF1R;RALA;CSF1;PIK3CD;RASGRP1;PLD2;TIAM1;GNG2;FASL;RASSF5;REL;RAC2;GNB4;PAK6;GNB5;TEK;RALGDS;EPHA2;PLA1A;ARF6;BCL2L1;MAPK3 108,Arrhythmogenic right ventricular cardiomyopathy (ARVC),Sep-72,0.054343806,0.137369065,5.72561111,CACNB3;JUP;ITGA3;ITGA2B;ITGA1;LMNA;CTNNA1;ITGAV;ITGB7 109,ErbB signaling pathway,Oct-84,0.058121171,0.144992504,5.29193777,PRKCG;CAMK2B;CDKN1A;JUN;SRC;PIK3CD;PAK6;AREG;HBEGF;MAPK3 110,Inositol phosphate metabolism,Sep-73,0.058421888,0.144992504,5.495820969,INPP4A;PI4K2B;SYNJ1;IMPA2;PIK3CD;SYNJ2;PIK3CG;PLCD1;MTM1 111,Epstein-Barr virus infection,22/229,0.063698333,0.156663468,4.034975228,RB1;ENTPD1;JUN;CDKN1A;H2-T22;H2-T10;H2-Q6;TNFAIP3;PIK3CD;CD3G;H2-Q2;RBPJ;ITGAL;MAPK14;TNF;TRAF5;E2F2;VIM;H2-D1;CD44;H2-Q10;TLR2 112,NOD-like receptor signaling pathway,20/205,0.065634629,0.159984407,4.058512282,GABARAPL1;JUN;RNASEL;CARD6;ITPR1;TRPV2;TNFAIP3;NOD1;ANTXR2;MEFV;MAPK14;TNF;AIM2;IL1B;CASP4;TRAF5;CASP1;TXNIP;BCL2L1;MAPK3 113,Chronic myeloid leukemia,Sep-76,0.071811847,0.171970476,4.867507642,RB1;CDKN1A;TGFB1;PIK3CD;E2F2;RUNX1;TGFBR2;MAPK3;BCL2L1 114,Renin secretion,Sep-76,0.071811847,0.171970476,4.867507642,PTGER4;PPP3CA;EDN1;ACE;GNAQ;ITPR1;ADRB1;AQP1;GNAI2 115,Hepatocellular carcinoma,17/171,0.073803127,0.175180124,3.963469842,RB1;PRKCG;WNT10B;CDKN1A;TGFB1;MGST3;GSTT3;PIK3CD;GSTT1;SMARCA2;ARID1B;TGFBR2;WNT11;E2F2;WNT3;BCL2L1;MAPK3 116,Hippo signaling pathway,16/159,0.074435511,0.175180124,4.003521126,WWTR1;WNT10B;TGFB1;ITGB2;PRKCZ;AREG;SMAD7;BBC3;TGFBR2;WNT11;PPP2R2C;CDH1;RASSF4;ID2;CTNNA1;WNT3 117,cAMP signaling pathway,20/211,0.082531309,0.192573053,3.599228616,CAMK2B;JUN;EDN1;F2R;PDE4C;ADCY4;ATP2B4;PIK3CD;NFATC1;ADRB1;FOS;ATP2B1;ADCY7;GNAI2;PLD2;TIAM1;ADORA2A;CREB3L2;RAC2;MAPK3 118,Progesterone-mediated oocyte maturation,Oct-90,0.084232904,0.19487782,4.255287516,STK10;RPS6KA2;ADCY4;PIK3CD;MAPK14;ADCY7;CPEB2;GNAI2;MAPK3;CPEB4 119,Asthma,25-Apr,0.085898827,0.196581173,6.424793487,IL10;IL5;CD40LG;TNF 120,Glutamatergic synapse,12/114,0.086409307,0.196581173,3.964863598,PRKCG;PPP3CA;GNG2;GNAQ;ITPR1;GNB4;ADCY4;GNB5;ADCY7;PLD2;GNAI2;MAPK3 121,Amphetamine addiction,Aug-68,0.089097217,0.19937328,4.434183375,PRKCG;CAMK2B;PPP3CA;ARC;JUN;CREB3L2;FOSB;FOS 122,Renal cell carcinoma,Aug-68,0.089097217,0.19937328,4.434183375,ARNT2;CDKN1A;JUN;TGFB1;EPAS1;PIK3CD;PAK6;MAPK3 123,Inflammatory mediator regulation of TRP channels,13/127,0.090727491,0.201370772,3.766957845,PRKCG;CAMK2B;PTGER4;PRKCH;SRC;ITPR1;TRPV2;ADCY4;PIK3CD;MAPK14;ADCY7;GNAQ;IL1B 124,Vascular smooth muscle contraction,14/140,0.094297172,0.206146761,3.611693107,PRKCG;CALCA;EDN1;PTGIR;PRKCH;ARHGEF12;ITPR1;ADCY4;ADCY7;GNA13;ADORA2A;ADORA2B;GNAQ;MAPK3 125,Primary immunodeficiency,May-36,0.094389543,0.206146761,5.23248297,CD40LG;CD8A;CD8B1;IL2RG;IL7R 126,Riboflavin metabolism,08-Feb,0.098275682,0.212930644,10.61970093,ENPP1;BLVRB 127,Pancreatic secretion,11/105,0.100189735,0.215368485,3.704304081,PRKCG;BST1;RAB3D;GNAQ;ITPR1;ATP2A3;ADCY4;ATP2B4;CD38;ATP2B1;ADCY7 128,Autophagy,13/130,0.104053273,0.221926122,3.460217548,GABARAPL1;DAPK2;ITPR1;EIF2AK3;PIK3CD;CFLAR;ATG14;VAMP8;ULK2;CTSD;TRP53INP2;BCL2L1;MAPK3 129,Type II diabetes mellitus,Jun-48,0.104984634,0.222176783,4.426254246,SOCS2;PIK3CD;MAFA;PRKCZ;TNF;MAPK3 130,Influenza A,16/168,0.107752496,0.226280242,3.228591369,JUN;RNASEL;EIF2AK3;PIK3CD;FURIN;MAPK14;TNF;TNFRSF1A;IFIH1;FASL;IFNG;IL1B;TNFSF10;CASP1;MAPK3;HSPA1A 131,Aldosterone-regulated sodium reabsorption,May-38,0.112737626,0.234941771,4.544954757,SLC9A3R2;PRKCG;PIK3CD;SFN;MAPK3 132,Prolactin signaling pathway,Aug-72,0.114497852,0.236802376,3.72502404,SOCS2;CISH;SRC;PIK3CD;FOS;TNFRSF11A;MAPK14;MAPK3 133,Mucin type O-glycan biosynthesis,28-Apr,0.118816215,0.242916068,4.877922824,GALNT3;GCNT1;GCNT4;B4GALT5 134,Other glycan degradation,18-Mar,0.119233528,0.242916068,5.842386343,NEU4;HEXB;FUCA2 135,Sulfur metabolism,09-Feb,0.120844843,0.24408349,8.291032816,ETHE1;SUOX 136,Prostate cancer,Oct-97,0.122439765,0.24408349,3.320120046,RB1;AR;CDKN1A;SPINT1;IL1R2;CREB3L2;PIK3CD;E2F2;MMP9;MAPK3 137,PPAR signaling pathway,Sep-85,0.122488784,0.24408349,3.419438185,CPT1A;FABP4;ACADL;OLR1;PPARG;PLIN2;ACSBG1;CD36;ANGPTL4 138,Bacterial invasion of epithelial cells,Aug-74,0.128515624,0.252509156,3.419277898,CDH1;SRC;CAV1;CLTC;CTNNA1;PIK3CD;ELMO2;VCL 139,Phosphatidylinositol signaling system,Oct-98,0.128566933,0.252509156,3.205899433,PRKCG;INPP4A;PI4K2B;SYNJ1;IMPA2;ITPR1;PIK3CD;SYNJ2;PLCD1;MTM1 140,Ferroptosis,May-40,0.132653589,0.258674498,3.965433971,PRNP;MAP1LC3A;FTH1;SLC3A2;SLC39A8 141,Complement and coagulation cascades,Sep-88,0.142791305,0.276468271,3.048822003,THBD;PROCR;ITGAM;F10;ITGB2;F2R;ITGAX;F13A1;F2RL2 142,GABAergic synapse,Sep-90,0.157214769,0.30225093,2.826225836,PRKCG;GABARAPL1;GNG2;SRC;ADCY4;GNB4;GNB5;ADCY7;GNAI2 143,Non-small cell lung cancer,Jul-66,0.159721407,0.304922687,2.991147881,RB1;PRKCG;CDKN1A;RASSF5;PIK3CD;E2F2;MAPK3 144,TGF-beta signaling pathway,Sep-91,0.164681843,0.310073805,2.721594199,TGFB1;IFNG;FST;ID2;TNF;THBS1;TGFBR2;MAPK3;SMAD7 145,Oocyte meiosis,11/116,0.164691215,0.310073805,2.598302569,CAMK2B;AR;PPP3CA;RPS6KA2;ITPR1;PPP2R5B;ADCY4;CPEB2;ADCY7;CPEB4;MAPK3 146,Long-term potentiation,Jul-67,0.168636099,0.315326405,2.854053742,PRKCG;CAMK2B;PPP3CA;RPS6KA2;GNAQ;ITPR1;MAPK3 147,Morphine addiction,Sep-92,0.172313501,0.320010787,2.621134579,PRKCG;GNG2;PDE4C;ADCY4;GNB4;GNB5;PDE7A;ADCY7;GNAI2 148,Regulation of lipolysis in adipocytes,Jun-56,0.178567197,0.329384087,2.840655817,FABP4;ADCY4;PIK3CD;ADRB1;ADCY7;GNAI2 149,Other types of O-glycan biosynthesis,22-Mar,0.185125703,0.339190046,3.657441052,LFNG;B4GALT1;EOGT 150,Cortisol synthesis and secretion,Jul-69,0.187095194,0.340513252,2.600528975,NR4A1;GNAQ;CREB3L2;ADCY4;ITPR1;ADCY7;LDLR 151,Hepatitis C,14/160,0.199298775,0.358264802,2.12680753,RB1;CDKN1A;RNASEL;EIF2AK3;PIK3CD;CFLAR;TNF;TNFRSF1A;FASL;IFNG;PPP2R2C;E2F2;LDLR;MAPK3 152,Neurotrophin signaling pathway,11/121,0.199473443,0.358264802,2.216123622,CAMK2B;JUN;FASL;IRAK2;RPS6KA2;MAPKAPK2;MATK;PIK3CD;IRAK3;MAPK14;MAPK3 153,Insulin resistance,10/110,0.213922569,0.381704977,2.119558128,CPT1A;PPP1R3B;RPS6KA2;CREB3L2;PIK3CD;PYGL;CD36;TNF;PRKCZ;TNFRSF1A 154,Gastric cancer,13/150,0.219943265,0.389899424,1.975512724,RB1;WNT10B;CDKN1A;TGFB1;JUP;PIK3CD;TGFBR2;WNT11;CDH1;CTNNA1;E2F2;WNT3;MAPK3 155,Cocaine addiction,May-48,0.225397746,0.396990869,2.37959445,JUN;CREB3L2;FOSB;RGS9;GNAI2 156,Long-term depression,Jun-61,0.232663648,0.407161384,2.185155293,PRKCG;GNA13;GNAQ;ITPR1;GNAI2;MAPK3 157,Gastric acid secretion,Jul-74,0.236497832,0.411235084,2.069483169,PRKCG;CAMK2B;GNAQ;ADCY4;ITPR1;ADCY7;GNAI2 158,Thyroid cancer,Apr-37,0.241505702,0.417285169,2.365148492,CDKN1A;CDH1;PPARG;MAPK3 159,Glioma,Jul-75,0.246859429,0.423852982,1.978301173,RB1;PRKCG;CAMK2B;CDKN1A;PIK3CD;E2F2;MAPK3 160,Folate biosynthesis,26-Mar,0.258070778,0.440333265,2.425786782,GCH1;MOCOS;GGH 161,Systemic lupus erythematosus,12/143,0.265871409,0.450825432,1.667555307,CD86;IL10;CD40LG;IFNG;FCGR4;CD80;CD28;ACTN4;TNF;HIST1H4D;TROVE2;HIST1H2BC 162,HIF-1 signaling pathway,9/104,0.274851889,0.463176331,1.680883083,PRKCG;CAMK2B;CDKN1A;EDN1;IFNG;PIK3CD;TEK;LTBR;MAPK3 163,Fat digestion and absorption,Apr-40,0.287467515,0.481463998,1.901913731,DGAT1;CD36;PLPP2;PLPP1 164,Glycosaminoglycan biosynthesis,May-53,0.290878786,0.484206759,1.76633592,B4GALT1;CHST12;XYLT1;EXTL3;B4GALT4 165,Staphylococcus aureus infection,Aug-95,0.3175822,0.521783752,1.448516334,IL10;FCGR3;ITGAM;SELPLG;FCGR4;ITGB2;FPR2;ITGAL 166,Endocrine and other factor-regulated calcium reabsorption,May-55,0.317982929,0.521783752,1.573174237,PRKCG;VDR;GNAQ;CLTC;ATP2B1 167,Purine metabolism,11/136,0.319260144,0.521783752,1.380100126,ENTPD1;NT5E;PDE4C;ADSSL1;ADCY4;ENPP1;AMPD1;AMPD3;PDE7A;ADCY7;XDH 168,Retrograde endocannabinoid signaling,12/150,0.32152433,0.521783752,1.355348257,PRKCG;FAAH;GNG2;GNAQ;ITPR1;GNB4;ADCY4;GNB5;MAPK14;ADCY7;GNAI2;MAPK3 169,Nitrogen metabolism,17-Feb,0.323008989,0.521783752,2.068167948,CAR13;CAR5B 170,Circadian rhythm,30-Mar,0.333999549,0.536363982,1.672599429,BHLHE40;RORA;ARNTL 171,Glycerophospholipid metabolism,Aug-97,0.338218355,0.539962636,1.338104768,PCYT1A;GPD2;LCLAT1;PLPP2;PLPP1;PLD3;PLD2;AGPAT4 172,Caffeine metabolism,06-Jan,0.3444409,0.543539687,2.925310636,XDH 173,Phosphonate and phosphinate metabolism,06-Jan,0.3444409,0.543539687,2.925310636,PCYT1A 174,Adipocytokine signaling pathway,Jun-71,0.35201389,0.552297656,1.323207663,CPT1A;ACSBG1;CD36;TNFRSF1B;TNF;TNFRSF1A 175,mTOR signaling pathway,12/154,0.354469773,0.552972846,1.203670668,PRKCG;PRR5;WNT10B;WNT11;RPS6KA2;ULK2;PIK3CD;SLC3A2;TNF;WNT3;TNFRSF1A;MAPK3 176,Endometrial cancer,May-58,0.359125392,0.557052455,1.326305514,CDKN1A;CDH1;CTNNA1;PIK3CD;MAPK3 177,Melanoma,Jun-72,0.364358246,0.561976278,1.260071815,RB1;CDKN1A;CDH1;PIK3CD;E2F2;MAPK3 178,Insulin secretion,Jul-86,0.367562143,0.56373295,1.217569069,PRKCG;CAMK2B;GNAQ;CREB3L2;ADCY4;KCNN4;ADCY7 179,Thyroid hormone synthesis,Jun-73,0.376723164,0.57455544,1.200170009,PRKCG;GNAQ;CREB3L2;ADCY4;ITPR1;ADCY7 180,Thyroid hormone signaling pathway,9/115,0.380450563,0.577016687,1.126553845,PRKCG;NCOA2;SRC;PIK3CD;SLC16A10;ITGAV;PLCD1;MED13L;MAPK3 181,Glucagon signaling pathway,8/102,0.390504785,0.586312194,1.098636052,CAMK2B;PPP3CA;CPT1A;GNAQ;CREB3L2;ITPR1;SIK1;PYGL 182,Starch and sucrose metabolism,Mar-33,0.390874796,0.586312194,1.289275632,AGL;ENPP1;PYGL 183,Ether lipid metabolism,Apr-47,0.397556796,0.593076531,1.177730724,PLPP2;PLD3;PLPP1;PLD2 184,Glycerolipid metabolism,May-61,0.400413332,0.59409152,1.121681045,DGAT1;LCLAT1;PLPP2;PLPP1;AGPAT4 185,Wnt signaling pathway,12/160,0.404760462,0.596855442,1.006812485,PRKCG;CAMK2B;WNT10B;PPP3CA;JUN;WNT11;TBL1XR1;CTNNBIP1;RAC2;NFATC2;NFATC1;WNT3 186,Pentose and glucuronate interconversions,Mar-34,0.409590549,0.596855442,1.185500669,UGDH;UGT1A7C;XYLB 187,Alzheimer disease,13/175,0.411012061,0.596855442,0.979553894,LRP1;ITPR1;EIF2AK3;ATP2A3;TNF;TNFRSF1A;PPP3CA;CASP7;GNAQ;IL1B;CAPN2;ATF6;MAPK3 188,Protein digestion and absorption,Jul-90,0.412857261,0.596855442,1.024112245,KCNK5;COL3A1;SLC7A8;COL4A2;SLC3A2;SLC16A10;KCNN4 189,ABC transporters,Apr-48,0.413207614,0.596855442,1.102725511,ABCA2;ABCB10;ABCA7;ABCB9 190,Breast cancer,11/147,0.415397654,0.59686084,0.975448039,RB1;WNT10B;JUN;CDKN1A;WNT11;PIK3CD;E2F2;FOS;DLL1;WNT3;MAPK3 191,Glycosaminoglycan degradation,21-Feb,0.422619439,0.60405815,1.244138799,HEXB;IDS 192,Amino sugar and nucleotide sugar metabolism,Apr-49,0.428768066,0.606495762,1.033067371,CHIT1;UGDH;NAGK;HEXB 193,Notch signaling pathway,Apr-49,0.428768066,0.606495762,1.033067371,LFNG;NUMBL;RBPJ;DLL1 194,Non-alcoholic fatty liver disease (NAFLD),11/151,0.450713683,0.634251728,0.859382126,XBP1;JUN;CASP7;TGFB1;FASL;DDIT3;IL1B;EIF2AK3;PIK3CD;TNF;TNFRSF1A 195,Cell cycle,9/123,0.459119669,0.642767536,0.843405799,RB1;CDKN1C;RBL2;CDKN1A;TGFB1;CDKN2C;E2F2;SFN;CDC14A 196,Metabolism of xenobiotics by cytochrome P450,May-66,0.46834971,0.6474224,0.853189913,MGST3;GSTT3;GSTT1;UGT1A7C;CBR3 197,Mannose type O-glycan biosynthesis,23-Feb,0.469559103,0.6474224,0.987893163,B4GALT1;FUT4 198,Terpenoid backbone biosynthesis,23-Feb,0.469559103,0.6474224,0.987893163,HMGCS1;IDI2 199,Porphyrin and chlorophyll metabolism,Mar-41,0.534000237,0.732011282,0.679480637,FECH;BLVRB;UGT1A7C 200,Synthesis and degradation of ketone bodies,11-Jan,0.538953362,0.732011282,0.848034607,HMGCS1 201,Taurine and hypotaurine metabolism,11-Jan,0.538953362,0.732011282,0.848034607,CDO1 202,Serotonergic synapse,9/132,0.545245255,0.736890864,0.608754988,PRKCG;GNG2;DUSP1;GNAQ;ITPR1;GNB4;GNB5;GNAI2;MAPK3 203,Protein processing in endoplasmic reticulum,11/163,0.554150273,0.740639669,0.585948797,PPP1R15A;XBP1;DDIT3;EDEM1;AMFR;HSPA4L;CAPN2;EIF2AK3;SEC24D;ATF6;HSPA1A 204,Ascorbate and aldarate metabolism,27-Feb,0.556157993,0.740639669,0.643894504,UGDH;UGT1A7C 205,Collecting duct acid secretion,27-Feb,0.556157993,0.740639669,0.643894504,SLC12A7;ATP6V0A1 206,Pyrimidine metabolism,Apr-58,0.561779653,0.744494395,0.585929284,ENTPD1;NT5E;ENPP1;CMPK2 207,Cytosolic DNA-sensing pathway,Apr-61,0.602240795,0.794259599,0.488064105,AIM2;IL1B;CCL4;CASP1 208,Insulin signaling pathway,9/139,0.608348049,0.798456814,0.47180088,SOCS2;PPP1R3B;PRKAR2B;PIK3CD;FLOT2;PYGL;PRKCZ;RHOQ;MAPK3 209,Fatty acid biosynthesis,14-Jan,0.626744916,0.816296508,0.492992703,ACSBG1 210,Basal cell carcinoma,Apr-63,0.627920391,0.816296508,0.432646592,WNT10B;CDKN1A;WNT11;WNT3 211,Glutathione metabolism,Apr-64,0.640355328,0.82851661,0.407485724,MGST3;IDH1;GSTT3;GSTT1 212,Galactose metabolism,Feb-32,0.649569967,0.832547422,0.394478889,B4GALT1;GALM 213,beta-Alanine metabolism,Feb-32,0.649569967,0.832547422,0.394478889,SMOX;CARNS1 214,SNARE interactions in vesicular transport,Feb-33,0.666259962,0.846302763,0.359286961,VAMP8;STX11 215,Arginine and proline metabolism,Mar-50,0.669602186,0.846302763,0.351041394,SMOX;CARNS1;CKB 216,Fatty acid degradation,Mar-50,0.669602186,0.846302763,0.351041394,CPT1A;ACADL;ACSBG1 217,Longevity regulating pathway,6/102,0.699879654,0.880493759,0.30569685,CREB3L2;ADCY4;PIK3CD;PPARG;ADCY7;HSPA1A 218,Herpes simplex virus 1 infection,27/433,0.707379237,0.885846476,0.315174975,ZFP689;RNASEL;H2-T22;ZFP763;SRC;ZFP768;H2-Q6;PIK3CD;ZFP949;H2-Q2;TNF;IFIH1;ZFP382;H2-T10;EIF2AK3;POU2F2;TNFRSF1A;FASL;IFNG;ZFP40;IL1B;TRAF5;LTA;H2-D1;H2-Q10;BCL2L1;TLR2 219,Renin-angiotensin system,Feb-36,0.712486244,0.888167784,0.273426412,ACE;ATP6AP2 220,Pantothenate and CoA biosynthesis,18-Jan,0.718379128,0.890363462,0.266829835,ENPP1 221,Signaling pathways regulating pluripotency of stem cells,8/137,0.720770422,0.890363462,0.278242105,WNT10B;WNT11;ID2;PIK3CD;MAPK14;KLF4;WNT3;MAPK3 222,Bile secretion,Apr-72,0.729770843,0.897420902,0.254002774,ADCY4;ADCY7;LDLR;AQP1 223,Ovarian steroidogenesis,Mar-57,0.75335401,0.922267465,0.215675626,ADCY4;ADCY7;LDLR 224,AMPK signaling pathway,7/126,0.760598211,0.926979069,0.220524973,CPT1A;PPP2R2C;CREB3L2;PPP2R5B;PIK3CD;PPARG;CD36 225,Proximal tubule bicarbonate reclamation,22-Jan,0.787529422,0.955535699,0.155953141,AQP1 226,Alcoholism,11/199,0.801093072,0.967692074,0.177635871,GNG2;ADORA2A;ADORA2B;CREB3L2;GNB4;FOSB;GNB5;HIST1H4D;GNAI2;HIST1H2BC;MAPK3 227,Hedgehog signaling pathway,Feb-44,0.810047352,0.972134239,0.137492129,KIF3A;CDON 228,Histidine metabolism,24-Jan,0.815453262,0.972134239,0.121607222,CARNS1 229,Vitamin digestion and absorption,24-Jan,0.815453262,0.972134239,0.121607222,SLC52A3 230,RNA degradation,Apr-83,0.823995027,0.978046272,0.13427744,BTG2;BTG1;XRN1;TOB1 231,Peroxisome,Apr-84,0.831030237,0.982126643,0.126768958,IDH1;ECH1;XDH;CRAT 232,Huntington disease,10/192,0.847667648,0.983974521,0.124253904,DNAH1;HIP1;POLR2A;DNAH8;GNAQ;CREB3L2;CLTC;ITPR1;PPARG;BBC3 233,RIG-I-like receptor signaling pathway,Mar-68,0.849550831,0.983974521,0.103089531,IFIH1;MAPK14;TNF 234,Butanoate metabolism,27-Jan,0.850615337,0.983974521,0.085301316,HMGCS1 235,Maturity onset diabetes of the young,27-Jan,0.850615337,0.983974521,0.085301316,MAFA 236,Phototransduction,27-Jan,0.850615337,0.983974521,0.085301316,RGS9 237,RNA polymerase,28-Jan,0.860779632,0.985335673,0.076107304,POLR2A 238,Cysteine and methionine metabolism,Feb-50,0.862619875,0.985335673,0.084367938,DNMT3A;CDO1 239,N-Glycan biosynthesis,Feb-50,0.862619875,0.985335673,0.084367938,B4GALT1;MAN2A1 240,Fatty acid elongation,29-Jan,0.870252803,0.989912563,0.068027486,ACOT7 241,Glyoxylate and dicarboxylate metabolism,31-Jan,0.887310423,0.99726281,0.054618026,GLDC 242,Chemical carcinogenesis,Apr-94,0.889263679,0.99726281,0.071411986,MGST3;GSTT3;GSTT1;UGT1A7C 243,Drug metabolism,5/114,0.893949013,0.99726281,0.070384669,MGST3;GSTT3;GSTT1;XDH;UGT1A7C 244,Biosynthesis of unsaturated fatty acids,Jan-32,0.894979445,0.99726281,0.049048975,ACOT7 245,Citrate cycle (TCA cycle),Jan-32,0.894979445,0.99726281,0.049048975,IDH1 246,Synaptic vesicle cycle,Mar-77,0.902151418,0.999993835,0.057160306,STXBP1;CLTC;ATP6V0A1 247,Cardiac muscle contraction,Mar-78,0.906832842,0.999993835,0.053560524,CACNB3;TPM4;TPM1 248,MicroRNAs in cancer,14/281,0.914338327,0.999993835,0.064148451,PRKCG;ST14;CDKN1A;TPM1;DNMT3A;KIF23;MMP9;THBS1;ZEB2;MIR146;E2F2;VIM;CD44;WNT3 249,Base excision repair,Jan-35,0.914996511,0.999993835,0.035799908,PARP4 250,Lysine degradation,Feb-59,0.916882608,0.999993835,0.041697813,NSD2;PLOD2 251,"Alanine, aspartate and glutamate metabolism",Jan-37,0.926174898,0.999993835,0.029186266,ADSSL1 252,Central carbon metabolism in cancer,Feb-64,0.937568955,0.999993835,0.028471123,PIK3CD;MAPK3 253,"Glycine, serine and threonine metabolism",Jan-40,0.940249215,0.999993835,0.021639574,GLDC 254,Basal transcription factors,Jan-43,0.951641853,0.999993835,0.01616326,TAF9B 255,Carbohydrate digestion and absorption,Jan-43,0.951641853,0.999993835,0.01616326,PIK3CD 256,Vasopressin-regulated water reabsorption,Jan-43,0.951641853,0.999993835,0.01616326,CREB3L2 257,Retinol metabolism,Mar-91,0.951677091,0.999993835,0.02310239,DGAT1;DHRS9;UGT1A7C 258,Proteasome,Jan-46,0.960863466,0.999993835,0.012148703,IFNG 259,Neuroactive ligand-receptor interaction,16/348,0.966096989,0.999993835,0.022660886,PTGER4;EDN1;CALCA;PTGIR;GZMA;F2R;ADRB1;GPR83;FPR2;CYSLTR1;EDNRB;ADORA2A;ADORA2B;PENK;S1PR4;F2RL2 260,Thermogenesis,9/231,0.978222277,0.999993835,0.012178863,CPT1A;RPS6KA2;CREB3L2;ADCY4;PPARG;MAPK14;SMARCA2;ADCY7;ARID1B 261,"Valine, leucine and isoleucine degradation",Jan-56,0.980671467,0.999993835,0.004856839,HMGCS1 262,Taste transduction,Feb-88,0.984984297,0.999993835,0.004811046,KCNK5;ADCY4 263,mRNA surveillance pathway,Feb-96,0.990795253,0.999993835,0.002689146,PPP2R2C;PPP2R5B 264,Glycolysis / Gluconeogenesis,Jan-67,0.991107375,0.999993835,0.0018512,GALM 265,Arachidonic acid metabolism,Jan-89,0.998118592,0.999993835,0.000292364,CBR3 266,Steroid hormone biosynthesis,Jan-89,0.998118592,0.999993835,0.000292364,UGT1A7C 267,Ubiquitin mediated proteolysis,2/138,0.999344786,0.999993835,0.000131439,HERC3;UBE2H 268,Parkinson disease,2/144,0.999553621,0.999993835,8.57E-05,ADORA2A;GNAI2 269,Ribosome biogenesis in eukaryotes,1/115,0.999698432,0.999993835,3.61E-05,XRN1 270,Spliceosome,1/132,0.999907281,0.999993835,9.65E-06,HSPA1A 271,Oxidative phosphorylation,1/134,0.999919098,0.999993835,8.29E-06,ATP6V0A1 272,RNA transport,1/167,0.999989087,0.999993835,8.94E-07,CYFIP1 273,Olfactory transduction,4/1133,0.999993835,0.999993835,2.82E-07,CAMK2B;RGS2;OLFR99;NCALD