lncRNAs that were significantly downregulated in CRC cells treated with simvastatin id NC_count Simv_count NC_fpkm Simv_fpkm log2(FC) Pvalue FDR significant Symbol NC-1_fpkm NC-2_fpkm NC-3_fpkm Simv-1_fpkm Simv-2_fpkm Simv-3_fpkm logNC-1_fpkm logNC-2_fpkm logNC-3_fpkm logSimv-1_fpkm logSimv-2_fpkm logSimv-3_fpkm ENST00000544868 1657.153333 0 157.7166667 0.001 -17.2669756 8.39E-20 6.67E-16 yes MALAT1 374.68 18.51 79.96 0.00000001 0.00000001 0.00000001 8.54951516 4.21023299 6.321206567 -26.57542476 -26.57542476 -26.57542476 ENST00000602971 45.69333333 0 1.173333333 0.001 -10.19639721 9.05E-13 2.40E-09 yes TUG1 1.46 0.37 1.69 0.00000001 0.00000001 0.00000001 0.545968369 -1.434402824 0.757023247 -26.57542476 -26.57542476 -26.57542476 ENST00000545440 18.98666667 0 1.086666667 0.001 -10.08569375 4.65E-05 0.010892681 yes SNHG1 2.06 0.00000001 1.2 0.00000001 0.00000001 0.00000001 1.042644337 -26.57542476 0.263034406 -26.57542476 -26.57542476 -26.57542476 ENST00000585033 8.623333333 0 0.623333333 0.001 -9.283860054 0.000240077 0.030173705 yes TYMSOS 0.25 1.11 0.51 0.00000001 0.00000001 0.00000001 -2 0.150559677 -0.971430848 -26.57542476 -26.57542476 -26.57542476 ENST00000601567 6.963333333 0 0.42 0.001 -8.714245518 0.000271066 0.032671638 yes CTC-444N24.6 0.62 0.29 0.35 0.00000001 0.00000001 0.00000001 -0.689659879 -1.785875195 -1.514573173 -26.57542476 -26.57542476 -26.57542476 ENST00000553985 8.57 0 0.153333333 0.001 -7.26052755 0.000405352 0.044785732 yes ZFHX2-AS1 0.06 0.32 0.08 0.00000001 0.00000001 0.00000001 -4.058893689 -1.64385619 -3.64385619 -26.57542476 -26.57542476 -26.57542476 ENST00000638356 105.6666667 11.33333333 9.466666667 0.876666667 -3.432756225 2.37E-06 0.001046127 yes LLNLF-96A1.1 18.53 3.44 6.43 1.21 0.23 1.19 4.211790976 1.782408565 2.684818738 0.275007047 -2.120294234 0.250961574 ENST00000569832 17.20333333 3.09 0.25 0.04 -2.64385619 0.000107285 0.017889593 yes SSTR5-AS1 0.26 0.23 0.26 0.03 0.03 0.06 -1.943416472 -2.120294234 -1.943416472 -5.058893689 -5.058893689 -4.058893689 ENST00000579473 24.99 4.836666667 1.763333333 0.313333333 -2.49253506 1.96E-05 0.005775337 yes SNHG29 1.71 1.68 1.9 0.4 0.09 0.45 0.773996325 0.748461233 0.925999419 -1.321928095 -3.473931188 -1.152003093 ENST00000522856 28.36333333 6.62 2.056666667 0.42 -2.291846756 6.75E-05 0.013314065 yes BAALC-AS1 2.82 2.18 1.17 0.45 0.33 0.48 1.495695163 1.124328135 0.22650853 -1.152003093 -1.59946207 -1.058893689 ENST00000607286 26.27666667 5.956666667 0.806666667 0.166666667 -2.275007047 0.000193786 0.025800204 yes CTD-2228K2.7 0.75 0.95 0.72 0.05 0.35 0.1 -0.415037499 -0.074000581 -0.473931188 -4.321928095 -1.514573173 -3.321928095 ENST00000622757 80.50333333 20.08 0.896666667 0.21 -2.094182439 2.52E-05 0.006915489 yes RP5-984P4.6 0.89 0.76 1.04 0.38 0.16 0.09 -0.168122759 -0.395928676 0.056583528 -1.395928676 -2.64385619 -3.473931188 ENST00000602813 24 6.666666667 7.726666667 1.926666667 -2.003739169 0.000137509 0.020257159 yes RNU11 10.41 5.06 7.71 1.52 2.3 1.96 3.379898164 2.339137385 2.94673086 0.604071324 1.201633861 0.970853654 ENST00000620791 60.51666667 16.46333333 1.156666667 0.296666667 -1.963058422 9.15E-07 0.000485394 yes RP11-617F23.1 0.99 1.16 1.32 0.31 0.36 0.22 -0.01449957 0.214124805 0.40053793 -1.689659879 -1.473931188 -2.184424571 ENST00000629651 152 43 0.913333333 0.24 -1.928107082 2.35E-07 0.000166755 yes LINC00950 0.73 0.93 1.08 0.23 0.2 0.29 -0.454031631 -0.104697379 0.111031312 -2.120294234 -2.321928095 -1.785875195 ENST00000611427 25.33333333 7.666666667 1.656666667 0.446666667 -1.891012851 0.000242755 0.030173705 yes RP11-506H21.5 2.32 1.21 1.44 0.49 0.4 0.45 1.214124805 0.275007047 0.526068812 -1.029146346 -1.321928095 -1.152003093 ENST00000553177 41.57 12.47333333 3.286666667 0.9 -1.868628239 8.29E-05 0.014647127 yes LINC01405 3.33 3.22 3.31 0.48 1.53 0.69 1.735522177 1.687060688 1.726831217 -1.058893689 0.613531653 -0.535331733 ENST00000593438 27.24 8.193333333 1.803333333 0.496666667 -1.860316263 0.000121293 0.018919297 yes HOXA-AS2 1.81 1.94 1.66 0.53 0.46 0.5 0.855989697 0.956056652 0.731183242 -0.915935735 -1.120294234 -1 ENST00000517411 66.03333333 21.46 4.323333333 1.263333333 -1.774908726 5.50E-05 0.011930923 yes MINCR 5.18 4.21 3.58 1.56 0.72 1.51 2.372952098 2.073820233 1.839959587 0.641546029 -0.473931188 0.59454855 ENST00000440490 44.44333333 14.45333333 3.693333333 1.093333333 -1.756190161 1.36E-05 0.0044967 yes ADIRF-AS1 4.15 3.24 3.69 1.14 1.15 0.99 2.053111336 1.695993813 1.883620816 0.189033824 0.201633861 -0.01449957 ENST00000599515 36 12 1.353333333 0.42 -1.688055994 0.000265068 0.032440236 yes RP5-1057I20.4 1.08 1.34 1.64 0.4 0.35 0.51 0.111031312 0.422233001 0.713695815 -1.321928095 -1.514573173 -0.971430848 ENST00000413904 70.57666667 24.73666667 2.516666667 0.793333333 -1.665515071 1.51E-05 0.004628914 yes NIFK-AS1 3.09 2.2 2.26 0.62 0.86 0.9 1.627606838 1.137503524 1.176322773 -0.689659879 -0.217591435 -0.152003093 ENST00000594624 74.41666667 27.34 2.176666667 0.723333333 -1.589387949 6.26E-05 0.013104449 yes LIPE-AS1 2.86 1.73 1.94 0.94 0.61 0.62 1.516015147 0.790772038 0.956056652 -0.089267338 -0.713118852 -0.689659879 ENST00000568654 69 26.33333333 4.836666667 1.646666667 -1.554464572 8.97E-05 0.015520227 yes RP11-49I11.1 6.64 4.08 3.79 1.7 1.79 1.45 2.731183242 2.028569152 1.922197848 0.765534746 0.839959587 0.5360529 ENST00000562471 109.3333333 42.00333333 2.216666667 0.786666667 -1.494567481 6.85E-06 0.002592996 yes RP11-7K24.3 2.09 2.1 2.46 0.8 0.93 0.63 1.063502942 1.070389328 1.298658316 -0.321928095 -0.104697379 -0.666576266 ENST00000552933 122.4766667 48.41666667 3.866666667 1.39 -1.476005517 1.41E-05 0.0044967 yes RP11-386G11.5 4.32 3.64 3.64 1.34 1.21 1.62 2.111031312 1.86393845 1.86393845 0.422233001 0.275007047 0.695993813 ENST00000416209 46.8 18.68666667 0.566666667 0.21 -1.432111013 0.000460046 0.047528078 yes PRKAR2A-AS1 0.65 0.46 0.59 0.28 0.18 0.17 -0.621488377 -1.120294234 -0.76121314 -1.836501268 -2.473931188 -2.556393349 ENST00000609791 58.66666667 25.33333333 3.266666667 1.266666667 -1.366782331 0.000428561 0.045107926 yes AC006946.17 3.99 2.85 2.96 0.95 1.49 1.36 1.996388746 1.510961919 1.565597176 -0.074000581 0.575312331 0.443606651 ENST00000449569 127.7533333 55.52333333 2.15 0.836666667 -1.361611796 6.66E-05 0.013314065 yes AC007246.3 2.81 1.83 1.81 0.78 0.92 0.81 1.49057013 0.871843649 0.855989697 -0.358453971 -0.120294234 -0.304006187 ENST00000513572 200.97 89.99 4.15 1.693333333 -1.29324534 2.40E-05 0.006806627 yes RP11-115D19.1 4.26 4.06 4.13 1.38 2.02 1.68 2.09085343 2.021479727 2.046141782 0.464668267 1.014355293 0.748461233 ENST00000412224 181.98 86.35666667 3.446666667 1.503333333 -1.197036847 4.90E-05 0.011144741 yes KTN1-AS1 3.38 3.51 3.45 1.5 1.66 1.35 1.757023247 1.811471031 1.786596362 0.584962501 0.731183242 0.432959407 ENST00000520944 2335.086667 1206.996667 153.0566667 71.86 -1.090805045 5.55E-05 0.011930923 yes SNHG6 177.94 131.19 150.04 71.57 72.87 71.14 7.475247047 7.035513944 7.229203358 6.161283075 6.187253086 6.152589069