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Extended Data Figure 5b: Kaplan-Meier analysis with log-rank comparison (knockdown of Ets21c)
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  Pairwise comparisons using Log-Rank test 

data:  mySurvivalData and group 

         TBI+RU TBI+veh Sham+RU
TBI+veh  <2e-16 -       -      
Sham+RU  <2e-16 0.65    -      
Sham+veh <2e-16 <2e-16  <2e-16 

P value adjustment method: BH 


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Extended Data Figure 5c (right panel): Two-way ANOVA (neuronal AP1 blockade)
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                    Df Sum Sq Mean Sq F value   Pr(>F)    
Condition            1   1415  1415.4  25.429 3.55e-06 ***
Treatment            1      1     1.0   0.018    0.894    
Condition:Treatment  1      1     1.5   0.026    0.871    
Residuals           69   3841    55.7                     
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Signif. codes:  0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1

non-signficant interaction, no post-hoc analyses performed. 


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Extended Data Figure 5e: Two-way ANOVA (glial JNK knockdown)
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                    Df Sum Sq Mean Sq F value  Pr(>F)    
Condition            1  920.5   920.5  20.749 6.1e-05 ***
Treatment            1   12.8    12.8   0.288   0.595    
Condition:Treatment  1    7.0     7.0   0.159   0.693    
Residuals           35 1552.8    44.4                    
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Signif. codes:  0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1

non-signficant interaction, no post-hoc analyses performed.