a#Variant position genome start Variant position genome stop Var. type Number WT base Var. base Region Gene ID Gene Name Gene start Gene stop Gene length Dir. WT AA Codon nr. Codon nr. E. coli Var. AA AA change Codon change Variant position gene start Variant position gene stop Antibiotic Reference PMID Source 6620 6620 SNP 1 g c coding Rv0005 gyrB 5240 7267 2028 + Asp 461 - His Asp461His gac/cac 1381 1381 fluoroquinolones (FQ) 24055765 HC_PhyResSE 6620 6620 SNP 1 g a coding Rv0005 gyrB 5240 7267 2028 + Asp 461 - Asn Asp461Asn gac/aac 1381 1381 fluoroquinolones (FQ) 19721073 HC_PhyResSE 6621 6621 SNP 1 a c coding Rv0005 gyrB 5240 7267 2028 + Asp 461 - Ala Asp461Ala gac/gcc 1382 1382 fluoroquinolones (FQ) 24055765 HC_PhyResSE 6734 6734 SNP 1 a g coding Rv0005 gyrB 5240 7267 2028 + Asn 499 - Asp Asn499Asp aac/gac 1495 1495 fluoroquinolones (FQ) 17412727 HC_PhyResSE 6735 6735 SNP 1 a c coding Rv0005 gyrB 5240 7267 2028 + Asn 499 - Thr Asn499Thr aac/acc 1496 1496 fluoroquinolones (FQ) 24055765 HC_PhyResSE 6736 6736 SNP 1 c g coding Rv0005 gyrB 5240 7267 2028 + Asn 499 - Lys Asn499Lys aac/aag 1497 1497 fluoroquinolones (FQ) 24055765 HC_PhyResSE 6737 6737 SNP 1 a c coding Rv0005 gyrB 5240 7267 2028 + Thr 500 - Pro Thr500Pro acc/ccc 1498 1498 fluoroquinolones (FQ) 24055765 HC_PhyResSE 6738 6738 SNP 1 c a coding Rv0005 gyrB 5240 7267 2028 + Thr 500 - Asn Thr500Asn acc/aac 1499 1499 fluoroquinolones (FQ) 24055765 HC_PhyResSE 6741 6741 SNP 1 a t coding Rv0005 gyrB 5240 7267 2028 + Glu 501 - Val Glu501Val gaa/gta 1502 1502 fluoroquinolones (FQ) 19721073 HC_PhyResSE 6742 6742 SNP 1 a t coding Rv0005 gyrB 5240 7267 2028 + Glu 501 - Asp Glu501Asp gaa/gat 1503 1503 fluoroquinolones (FQ) 19721073 HC_PhyResSE 6750 6750 SNP 1 c t coding Rv0005 gyrB 5240 7267 2028 + Ala 504 - Val Ala504Val gcg/gtg 1511 1511 fluoroquinolones (FQ) 24055765 HC_PhyResSE 7563 7563 SNP 1 g t coding Rv0006 gyrA 7302 9818 2517 + Gly 88 - Cys Gly88Cys ggc/tgc 262 262 fluoroquinolones (FQ) 24055765 HC_PhyResSE 7564 7564 SNP 1 g c coding Rv0006 gyrA 7302 9818 2517 + Gly 88 - Ala Gly88Ala ggc/gcc 263 263 fluoroquinolones (FQ) 24055765 HC_PhyResSE 7570 7570 SNP 1 c t coding Rv0006 gyrA 7302 9818 2517 + Ala 90 - Val Ala90Val gcg/gtg 269 269 fluoroquinolones (FQ) 21300839 HC_PhyResSE 7572 7572 SNP 1 t c coding Rv0006 gyrA 7302 9818 2517 + Ser 91 - Pro Ser91Pro tcg/ccg 271 271 fluoroquinolones (FQ) 21562102 HC_PhyResSE 7581 7581 SNP 1 g c coding Rv0006 gyrA 7302 9818 2517 + Asp 94 - His Asp94His gac/cac 280 280 fluoroquinolones (FQ) 21562102 HC_PhyResSE 7581 7581 SNP 1 g a coding Rv0006 gyrA 7302 9818 2517 + Asp 94 - Asn Asp94Asn gac/aac 280 280 fluoroquinolones (FQ) 21562102 HC_PhyResSE 7581 7581 SNP 1 g t coding Rv0006 gyrA 7302 9818 2517 + Asp 94 - Tyr Asp94Tyr gac/tac 280 280 fluoroquinolones (FQ) 21562102 HC_PhyResSE 7582 7582 SNP 1 a g coding Rv0006 gyrA 7302 9818 2517 + Asp 94 - Gly Asp94Gly gac/ggc 281 281 fluoroquinolones (FQ) 21300839 HC_PhyResSE 7582 7582 SNP 1 a c coding Rv0006 gyrA 7302 9818 2517 + Asp 94 - Ala Asp94Ala gac/gcc 281 281 fluoroquinolones (FQ) 21300839 HC_PhyResSE 760314 760314 SNP 1 g t coding Rv0667 rpoB 759807 763325 3519 + Val 170 146 Phe Val170Phe gtc/ttc 508 508 rifampicin (RMP) 11136757 HC_PhyResSE 761101 761101 SNP 1 a t coding Rv0667 rpoB 759807 763325 3519 + Gln 432 513 Leu Gln432Leu caa/cta 1295 1295 rifampicin (RMP) 16672384 HC_PhyResSE 761109 761109 SNP 1 g t coding Rv0667 rpoB 759807 763325 3519 + Asp 435 516 Tyr Asp435Tyr gac/tac 1303 1303 rifampicin (RMP) 11880449 HC_PhyResSE 761110 761110 SNP 1 a g coding Rv0667 rpoB 759807 763325 3519 + Asp 435 516 Gly Asp435Gly gac/ggc 1304 1304 rifampicin (RMP) 24055765 HC_PhyResSE 761110 761110 SNP 1 a t coding Rv0667 rpoB 759807 763325 3519 + Asp 435 516 Val Asp435Val gac/gtc 1304 1304 rifampicin (RMP) 21300839 HC_PhyResSE 761139 761139 SNP 1 c a coding Rv0667 rpoB 759807 763325 3519 + His 445 526 Asn His445Asn cac/aac 1333 1333 rifampicin (RMP) 14729930 HC_PhyResSE 761139 761139 SNP 1 c g coding Rv0667 rpoB 759807 763325 3519 + His 445 526 Asp His445Asp cac/gac 1333 1333 rifampicin (RMP) 21300839 HC_PhyResSE 761139 761139 SNP 1 c t coding Rv0667 rpoB 759807 763325 3519 + His 445 526 Tyr His445Tyr cac/tac 1333 1333 rifampicin (RMP) 21300839 HC_PhyResSE 761140 761140 SNP 1 a c coding Rv0667 rpoB 759807 763325 3519 + His 445 526 Pro His445Pro cac/ccc 1334 1334 rifampicin (RMP) 7759399 HC_PhyResSE 761140 761140 SNP 1 a g coding Rv0667 rpoB 759807 763325 3519 + His 445 526 Arg His445Arg cac/cgc 1334 1334 rifampicin (RMP) 9003625 HC_PhyResSE 761155 761155 SNP 1 c g coding Rv0667 rpoB 759807 763325 3519 + Ser 450 531 Trp Ser450Trp tcg/tgg 1349 1349 rifampicin (RMP) 7759399 HC_PhyResSE 761155 761155 SNP 1 c t coding Rv0667 rpoB 759807 763325 3519 + Ser 450 531 Leu Ser450Leu tcg/ttg 1349 1349 rifampicin (RMP) 21300839 HC_PhyResSE 761161 761161 SNP 1 t c coding Rv0667 rpoB 759807 763325 3519 + Leu 452 533 Pro Leu452Pro ctg/ccg 1355 1355 rifampicin (RMP) 8913484 HC_PhyResSE 761277 761277 SNP 1 a t coding Rv0667 rpoB 759807 763325 3519 + Ile 491 572 Phe Ile491Phe atc/ttc 1471 1471 rifampicin (RMP) 10565894 HC_PhyResSE 781687 781687 SNP 1 a g coding Rv0682 rpsL 781560 781934 375 + Lys 43 - Arg Lys43Arg aag/agg 128 128 streptomycin (SM) 22646308 HC_PhyResSE 781822 781822 SNP 1 a g coding Rv0682 rpsL 781560 781934 375 + Lys 88 - Arg Lys88Arg aag/agg 263 263 streptomycin (SM) 22646308 HC_PhyResSE 1473246 1473246 SNP 1 a g ribosomal MTB000019 rrs 1471846 1473382 1537 + - - - - --- - 1401 1401 amikacin (AMK) kanamycin (KAN) capreomycin (CPR) 21300839 HC_PhyResSE 1473247 1473247 SNP 1 c t ribosomal MTB000019 rrs 1471846 1473382 1537 + - - - - --- - 1402 1402 amikacin (AMK) kanamycin (KAN) capreomycin (CPR) 16048924 HC_PhyResSE 1473329 1473329 SNP 1 g t ribosomal MTB000019 rrs 1471846 1473382 1537 + - - - - --- - 1484 1484 amikacin (AMK) kanamycin (KAN) capreomycin (CPR) 21562102 HC_PhyResSE 1673425 1673425 SNP 1 c t intergenic Rv1483 fabG1 1673440 1674183 744 + - - - - --- - -15 -15 isoniazid (INH) 21300839 HC_PhyResSE 1673432 1673432 SNP 1 t a intergenic Rv1483 fabG1 1673440 1674183 744 + - - - - --- - -8 -8 isoniazid (INH) 19494067 HC_PhyResSE 1673432 1673432 SNP 1 t c intergenic Rv1483 fabG1 1673440 1674183 744 + - - - - --- - -8 -8 isoniazid (INH) 21300839 HC_PhyResSE 1674481 1674481 SNP 1 t g coding Rv1484 inhA 1674202 1675011 810 + Ser 94 - Ala Ser94Ala tcg/gcg 280 280 isoniazid (INH) ethionamide (ETH) 24055765 HC_PhyResSE 2155168 2155168 SNP 1 c g coding Rv1908c katG 2156111 2153889 2223 - Ser 315 - Thr Ser315Thr agc/acc 944 944 isoniazid (INH) 8878604 HC_PhyResSE 2155168 2155168 SNP 1 c t coding Rv1908c katG 2156111 2153889 2223 - Ser 315 - Asn Ser315Asn agc/aac 944 944 isoniazid (INH) 9210694 HC_PhyResSE 2155168 2155168 SNP 1 c a coding Rv1908c katG 2156111 2153889 2223 - Ser 315 - Ile Ser315Ile agc/atc 944 944 isoniazid (INH) 9210694 HC_PhyResSE 2155169 2155169 SNP 1 t c coding Rv1908c katG 2156111 2153889 2223 - Ser 315 - Gly Ser315Gly agc/ggc 943 943 isoniazid (INH) 8878604 HC_PhyResSE 2155214 2155214 SNP 1 a c coding Rv1908c katG 2156111 2153889 2223 - Trp 300 - Gly Trp300Gly tgg/ggg 898 898 isoniazid (INH) 24055765 HC_PhyResSE 2155289 2155289 SNP 1 t g coding Rv1908c katG 2156111 2153889 2223 - Thr 275 - Pro Thr275Pro acc/ccc 823 823 isoniazid (INH) 24055765 HC_PhyResSE 2288683 2288683 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - STOP 187 - Arg STOP187Arg tga/cga 559 559 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288697 2288697 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Leu 182 - Ser Leu182Ser ttg/tcg 545 545 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288703 2288703 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Val 180 - Ala Val180Ala gtc/gcc 539 539 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288703 2288703 SNP 1 a c coding Rv2043c pncA 2289241 2288681 561 - Val 180 - Gly Val180Gly gtc/ggc 539 539 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288718 2288718 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Met 175 - Thr Met175Thr atg/acg 524 524 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288719 2288719 SNP 1 t c coding Rv2043c pncA 2289241 2288681 561 - Met 175 - Val Met175Val atg/gtg 523 523 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288740 2288740 SNP 1 t g coding Rv2043c pncA 2289241 2288681 561 - Thr 168 - Pro Thr168Pro acc/ccc 502 502 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288752 2288752 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Ser 164 - Pro Ser164Pro tcg/ccg 490 490 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288754 2288754 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Val 163 - Ala Val163Ala gtg/gcg 488 488 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288761 2288761 SNP 1 c g coding Rv2043c pncA 2289241 2288681 561 - Ala 161 - Pro Ala161Pro gcg/ccg 481 481 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288764 2288764 SNP 1 t g coding Rv2043c pncA 2289241 2288681 561 - Thr 160 - Pro Thr160Pro aca/cca 478 478 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288772 2288772 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Val 157 - Ala Val157Ala gtg/gcg 470 470 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288772 2288772 SNP 1 a c coding Rv2043c pncA 2289241 2288681 561 - Val 157 - Gly Val157Gly gtg/ggg 470 470 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288778 2288778 SNP 1 a c coding Rv2043c pncA 2289241 2288681 561 - Val 155 - Gly Val155Gly gtg/ggg 464 464 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288779 2288779 SNP 1 c t coding Rv2043c pncA 2289241 2288681 561 - Val 155 - Met Val155Met gtg/atg 463 463 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288805 2288805 SNP 1 g a coding Rv2043c pncA 2289241 2288681 561 - Ala 146 - Val Ala146Val gcg/gtg 437 437 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288806 2288806 SNP 1 c g coding Rv2043c pncA 2289241 2288681 561 - Ala 146 - Pro Ala146Pro gcg/ccg 436 436 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288817 2288817 SNP 1 g t coding Rv2043c pncA 2289241 2288681 561 - Thr 142 - Lys Thr142Lys acg/aag 425 425 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288817 2288817 SNP 1 g a coding Rv2043c pncA 2289241 2288681 561 - Thr 142 - Met Thr142Met acg/atg 425 425 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288818 2288818 SNP 1 t c coding Rv2043c pncA 2289241 2288681 561 - Thr 142 - Ala Thr142Ala acg/gcg 424 424 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288823 2288823 SNP 1 c g coding Rv2043c pncA 2289241 2288681 561 - Arg 140 - Pro Arg140Pro cgc/ccc 419 419 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288826 2288826 SNP 1 a c coding Rv2043c pncA 2289241 2288681 561 - Val 139 - Gly Val139Gly gtg/ggg 416 416 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288827 2288827 SNP 1 c g coding Rv2043c pncA 2289241 2288681 561 - Val 139 - Leu Val139Leu gtg/ctg 415 415 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288828 2288828 SNP 1 a c coding Rv2043c pncA 2289241 2288681 561 - Cys 138 - Trp Cys138Trp tgt/tgg 414 414 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288830 2288830 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Cys 138 - Arg Cys138Arg tgt/cgt 412 412 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288832 2288832 SNP 1 t c coding Rv2043c pncA 2289241 2288681 561 - His 137 - Arg His137Arg cat/cgt 410 410 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288832 2288832 SNP 1 t g coding Rv2043c pncA 2289241 2288681 561 - His 137 - Pro His137Pro cat/cct 410 410 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288833 2288833 SNP 1 g c coding Rv2043c pncA 2289241 2288681 561 - His 137 - Asp His137Asp cat/gat 409 409 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288838 2288838 SNP 1 g t coding Rv2043c pncA 2289241 2288681 561 - Thr 135 - Asn Thr135Asn acc/aac 404 404 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288839 2288839 SNP 1 t g coding Rv2043c pncA 2289241 2288681 561 - Thr 135 - Pro Thr135Pro acc/ccc 403 403 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288841 2288841 SNP 1 g a coding Rv2043c pncA 2289241 2288681 561 - Ala 134 - Val Ala134Val gcc/gtc 401 401 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288847 2288847 SNP 1 c g coding Rv2043c pncA 2289241 2288681 561 - Gly 132 - Ala Gly132Ala ggt/gct 395 395 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288847 2288847 SNP 1 c t coding Rv2043c pncA 2289241 2288681 561 - Gly 132 - Asp Gly132Asp ggt/gat 395 395 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288848 2288848 SNP 1 c a coding Rv2043c pncA 2289241 2288681 561 - Gly 132 - Cys Gly132Cys ggt/tgt 394 394 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288853 2288853 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Val 130 - Ala Val130Ala gtg/gcg 389 389 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288853 2288853 SNP 1 a c coding Rv2043c pncA 2289241 2288681 561 - Val 130 - Gly Val130Gly gtg/ggg 389 389 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288857 2288857 SNP 1 c a coding Rv2043c pncA 2289241 2288681 561 - Asp 129 - Tyr Asp129Tyr gat/tat 385 385 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288868 2288868 SNP 1 a c coding Rv2043c pncA 2289241 2288681 561 - Val 125 - Gly Val125Gly gtc/ggc 374 374 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288869 2288869 SNP 1 c a coding Rv2043c pncA 2289241 2288681 561 - Val 125 - Phe Val125Phe gtc/ttc 373 373 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288874 2288874 SNP 1 c g coding Rv2043c pncA 2289241 2288681 561 - Arg 123 - Pro Arg123Pro cgc/ccc 368 368 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288880 2288880 SNP 1 c g coding Rv2043c pncA 2289241 2288681 561 - Arg 121 - Pro Arg121Pro cgg/ccg 362 362 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288883 2288883 SNP 1 a t coding Rv2043c pncA 2289241 2288681 561 - Leu 120 - Gln Leu120Gln ctg/cag 359 359 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288883 2288883 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Leu 120 - Pro Leu120Pro ctg/ccg 359 359 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288886 2288886 SNP 1 c g coding Rv2043c pncA 2289241 2288681 561 - Trp 119 - Ser Trp119Ser tgg/tcg 356 356 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288886 2288886 SNP 1 c t coding Rv2043c pncA 2289241 2288681 561 - Trp 119 - STOP Trp119STOP tgg/tag 356 356 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288887 2288887 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Trp 119 - Arg Trp119Arg tgg/cgg 355 355 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288887 2288887 SNP 1 a c coding Rv2043c pncA 2289241 2288681 561 - Trp 119 - Gly Trp119Gly tgg/ggg 355 355 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288895 2288895 SNP 1 a c coding Rv2043c pncA 2289241 2288681 561 - Leu 116 - Arg Leu116Arg ctg/cgg 347 347 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288895 2288895 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Leu 116 - Pro Leu116Pro ctg/ccg 347 347 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288920 2288920 SNP 1 c t coding Rv2043c pncA 2289241 2288681 561 - Gly 108 - Arg Gly108Arg gga/aga 322 322 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288920 2288920 SNP 1 c g coding Rv2043c pncA 2289241 2288681 561 - Gly 108 - Arg Gly108Arg gga/cga 322 322 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288928 2288928 SNP 1 c t coding Rv2043c pncA 2289241 2288681 561 - Gly 105 - Asp Gly105Asp ggc/gac 314 314 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288930 2288930 SNP 1 g t coding Rv2043c pncA 2289241 2288681 561 - Ser 104 - Arg Ser104Arg agc/aga 312 312 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288931 2288931 SNP 1 c a coding Rv2043c pncA 2289241 2288681 561 - Ser 104 - Ile Ser104Ile agc/atc 311 311 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288933 2288933 SNP 1 g c coding Rv2043c pncA 2289241 2288681 561 - Tyr 103 - STOP Tyr103STOP tac/tag 309 309 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288934 2288934 SNP 1 t c coding Rv2043c pncA 2289241 2288681 561 - Tyr 103 - Cys Tyr103Cys tac/tgc 308 308 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288935 2288935 SNP 1 a c coding Rv2043c pncA 2289241 2288681 561 - Tyr 103 - Asp Tyr103Asp tac/gac 307 307 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288938 2288938 SNP 1 c t coding Rv2043c pncA 2289241 2288681 561 - Ala 102 - Thr Ala102Thr gcg/acg 304 304 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288944 2288944 SNP 1 t c coding Rv2043c pncA 2289241 2288681 561 - Thr 100 - Ala Thr100Ala acc/gcc 298 298 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288944 2288944 SNP 1 t g coding Rv2043c pncA 2289241 2288681 561 - Thr 100 - Pro Thr100Pro acc/ccc 298 298 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288945 2288945 SNP 1 g t coding Rv2043c pncA 2289241 2288681 561 - Tyr 99 - STOP Tyr99STOP tac/taa 297 297 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288952 2288952 SNP 1 c g coding Rv2043c pncA 2289241 2288681 561 - Gly 97 - Ala Gly97Ala ggt/gct 290 290 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288952 2288952 SNP 1 c t coding Rv2043c pncA 2289241 2288681 561 - Gly 97 - Asp Gly97Asp ggt/gat 290 290 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288954 2288954 SNP 1 c t coding Rv2043c pncA 2289241 2288681 561 - Lys 96 - Asn Lys96Asn aag/aac 288 288 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288955 2288955 SNP 1 t c coding Rv2043c pncA 2289241 2288681 561 - Lys 96 - Arg Lys96Arg aag/agg 287 287 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288955 2288955 SNP 1 t g coding Rv2043c pncA 2289241 2288681 561 - Lys 96 - Thr Lys96Thr aag/acg 287 287 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288956 2288956 SNP 1 t g coding Rv2043c pncA 2289241 2288681 561 - Lys 96 - Gln Lys96Gln aag/cag 286 286 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288957 2288957 SNP 1 g c coding Rv2043c pncA 2289241 2288681 561 - Tyr 95 - STOP Tyr95STOP tac/tag 285 285 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288960 2288960 SNP 1 g t coding Rv2043c pncA 2289241 2288681 561 - Phe 94 - Leu Phe94Leu ttc/tta 282 282 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288960 2288960 SNP 1 g c coding Rv2043c pncA 2289241 2288681 561 - Phe 94 - Leu Phe94Leu ttc/ttg 282 282 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288961 2288961 SNP 1 a c coding Rv2043c pncA 2289241 2288681 561 - Phe 94 - Cys Phe94Cys ttc/tgc 281 281 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288961 2288961 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Phe 94 - Ser Phe94Ser ttc/tcc 281 281 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288962 2288962 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Phe 94 - Leu Phe94Leu ttc/ctc 280 280 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288971 2288971 SNP 1 c a coding Rv2043c pncA 2289241 2288681 561 - Glu 91 - STOP Glu91STOP gag/tag 271 271 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288988 2288988 SNP 1 a c coding Rv2043c pncA 2289241 2288681 561 - Leu 85 - Arg Leu85Arg ctg/cgg 254 254 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288997 2288997 SNP 1 t c coding Rv2043c pncA 2289241 2288681 561 - His 82 - Arg His82Arg cat/cgt 245 245 pyrazinamide (PZA) 25336456 HC_PhyResSE 2288998 2288998 SNP 1 g c coding Rv2043c pncA 2289241 2288681 561 - His 82 - Asp His82Asp cat/gat 244 244 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289000 2289000 SNP 1 a c coding Rv2043c pncA 2289241 2288681 561 - Phe 81 - Cys Phe81Cys ttc/tgc 242 242 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289000 2289000 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Phe 81 - Ser Phe81Ser ttc/tcc 242 242 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289001 2289001 SNP 1 a c coding Rv2043c pncA 2289241 2288681 561 - Phe 81 - Val Phe81Val ttc/gtc 241 241 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289028 2289028 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Cys 72 - Arg Cys72Arg tgc/cgc 214 214 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289029 2289029 SNP 1 a t coding Rv2043c pncA 2289241 2288681 561 - His 71 - Gln His71Gln cat/caa 213 213 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289030 2289030 SNP 1 t c coding Rv2043c pncA 2289241 2288681 561 - His 71 - Arg His71Arg cat/cgt 212 212 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289038 2289038 SNP 1 c g coding Rv2043c pncA 2289241 2288681 561 - Trp 68 - Cys Trp68Cys tgg/tgc 204 204 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289038 2289038 SNP 1 c a coding Rv2043c pncA 2289241 2288681 561 - Trp 68 - Cys Trp68Cys tgg/tgt 204 204 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289039 2289039 SNP 1 c t coding Rv2043c pncA 2289241 2288681 561 - Trp 68 - STOP Trp68STOP tgg/tag 203 203 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289043 2289043 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Ser 67 - Pro Ser67Pro tcg/ccg 199 199 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289050 2289050 SNP 1 a c coding Rv2043c pncA 2289241 2288681 561 - Tyr 64 - STOP Tyr64STOP tat/tag 192 192 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289057 2289057 SNP 1 g a coding Rv2043c pncA 2289241 2288681 561 - Pro 62 - Leu Pro62Leu ccg/ctg 185 185 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289068 2289068 SNP 1 g t coding Rv2043c pncA 2289241 2288681 561 - Phe 58 - Leu Phe58Leu ttc/tta 174 174 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289068 2289068 SNP 1 g c coding Rv2043c pncA 2289241 2288681 561 - Phe 58 - Leu Phe58Leu ttc/ttg 174 174 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289070 2289070 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Phe 58 - Leu Phe58Leu ttc/ctc 172 172 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289071 2289071 SNP 1 g c coding Rv2043c pncA 2289241 2288681 561 - His 57 - Gln His57Gln cac/ag 171 171 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289072 2289072 SNP 1 t c coding Rv2043c pncA 2289241 2288681 561 - His 57 - Arg His57Arg cac/cgc 170 170 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289072 2289072 SNP 1 t g coding Rv2043c pncA 2289241 2288681 561 - His 57 - Pro His57Pro cac/ccc 170 170 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289081 2289081 SNP 1 g c coding Rv2043c pncA 2289241 2288681 561 - Pro 54 - Arg Pro54Arg ccg/cgg 161 161 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289081 2289081 SNP 1 g t coding Rv2043c pncA 2289241 2288681 561 - Pro 54 - Gln Pro54Gln ccg/cag 161 161 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289082 2289082 SNP 1 g a coding Rv2043c pncA 2289241 2288681 561 - Pro 54 - Ser Pro54Ser ccg/tcg 160 160 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289089 2289089 SNP 1 g t coding Rv2043c pncA 2289241 2288681 561 - His 51 - Gln His51Gln cac/caa 153 153 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289090 2289090 SNP 1 t c coding Rv2043c pncA 2289241 2288681 561 - His 51 - Arg His51Arg cac/cgc 152 152 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289090 2289090 SNP 1 t g coding Rv2043c pncA 2289241 2288681 561 - His 51 - Pro His51Pro cac/ccc 152 152 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289091 2289091 SNP 1 g a coding Rv2043c pncA 2289241 2288681 561 - His 51 - Tyr His51Tyr cac/tac 151 151 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289097 2289097 SNP 1 c t coding Rv2043c pncA 2289241 2288681 561 - Asp 49 - Asn Asp49Asn gac/aac 145 145 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289100 2289100 SNP 1 t c coding Rv2043c pncA 2289241 2288681 561 - Lys 48 - Glu Lys48Glu aag/gag 142 142 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289100 2289100 SNP 1 t a coding Rv2043c pncA 2289241 2288681 561 - Lys 48 - STOP Lys48STOP aag/tag 142 142 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289103 2289103 SNP 1 t g coding Rv2043c pncA 2289241 2288681 561 - Thr 47 - Pro Thr47Pro acc/ccc 139 139 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289111 2289111 SNP 1 a c coding Rv2043c pncA 2289241 2288681 561 - Val 44 - Gly Val44Gly gtc/ggc 131 131 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289133 2289133 SNP 1 c a coding Rv2043c pncA 2289241 2288681 561 - Glu 37 - top Glu37top gaa/taa 109 109 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289138 2289138 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Leu 35 - Pro Leu35Pro ctg/ccg 104 104 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289140 2289140 SNP 1 g c coding Rv2043c pncA 2289241 2288681 561 - Tyr 34 - STOP Tyr34STOP tac/tag 102 102 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289150 2289150 SNP 1 a c coding Rv2043c pncA 2289241 2288681 561 - Ile 31 - Ser Ile31Ser atc/agc 92 92 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289162 2289162 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Leu 27 - Pro Leu27Pro ctg/ccg 80 80 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289171 2289171 SNP 1 c t coding Rv2043c pncA 2289241 2288681 561 - Gly 24 - Asp Gly24Asp ggc/gac 71 71 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289180 2289180 SNP 1 a c coding Rv2043c pncA 2289241 2288681 561 - Val 21 - Gly Val21Gly gta/gga 62 62 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289186 2289186 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Leu 19 - Pro Leu19Pro ctg/ccg 56 56 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289193 2289193 SNP 1 c t coding Rv2043c pncA 2289241 2288681 561 - Gly 17 - Ser Gly17Ser ggc/agc 49 49 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289200 2289200 SNP 1 g t coding Rv2043c pncA 2289241 2288681 561 - Cys 14 - STOP Cys14STOP tgc/tga 42 42 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289202 2289202 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Cys 14 - Arg Cys14Arg tgc/cgc 40 40 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289203 2289203 SNP 1 g c coding Rv2043c pncA 2289241 2288681 561 - Phe 13 - Leu Phe13Leu ttc/ttg 39 39 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289206 2289206 SNP 1 g c coding Rv2043c pncA 2289241 2288681 561 - Asp 12 - Glu Asp12Glu gac/gag 36 36 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289207 2289207 SNP 1 t g coding Rv2043c pncA 2289241 2288681 561 - Asp 12 - Ala Asp12Ala gac/gcc 35 35 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289214 2289214 SNP 1 g t coding Rv2043c pncA 2289241 2288681 561 - Gln 10 - Lys Gln10Lys cag/aag 28 28 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289218 2289218 SNP 1 g t coding Rv2043c pncA 2289241 2288681 561 - Asp 8 - Glu Asp8Glu gac/gaa 24 24 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289219 2289219 SNP 1 t g coding Rv2043c pncA 2289241 2288681 561 - Asp 8 - Ala Asp8Ala gac/gcc 23 23 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289220 2289220 SNP 1 c t coding Rv2043c pncA 2289241 2288681 561 - Asp 8 - Asn Asp8Asn gac/aac 22 22 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289222 2289222 SNP 1 a c coding Rv2043c pncA 2289241 2288681 561 - Val 7 - Gly Val7Gly gtc/ggc 20 20 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289223 2289223 SNP 1 c a coding Rv2043c pncA 2289241 2288681 561 - Val 7 - Phe Val7Phe gtc/ttc 19 19 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289225 2289225 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Ile 6 - Thr Ile6Thr atc/acc 17 17 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289231 2289231 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Leu 4 - Ser Leu4Ser ttg/tcg 11 11 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289234 2289234 SNP 1 g t coding Rv2043c pncA 2289241 2288681 561 - Ala 3 - Glu Ala3Glu gcg/gag 8 8 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289239 2289239 SNP 1 c t coding Rv2043c pncA 2289241 2288681 561 - Met 1 - Ile Met1Ile atg/ata 3 3 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289240 2289240 SNP 1 a t coding Rv2043c pncA 2289241 2288681 561 - Met 1 - Lys Met1Lys atg/aag 2 2 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289240 2289240 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Met 1 - Thr Met1Thr atg/acg 2 2 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289248 2289248 SNP 1 a g intergenic Rv2043c pncA 2289241 2288681 561 - - - - - --- - -7 -7 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289248 2289248 SNP 1 a c intergenic Rv2043c pncA 2289241 2288681 561 - - - - - --- - -7 -7 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289252 2289252 SNP 1 t c intergenic Rv2043c pncA 2289241 2288681 561 - - - - - --- - -11 -11 pyrazinamide (PZA) 22646308 HC_PhyResSE 2289252 2289252 SNP 1 t g intergenic Rv2043c pncA 2289241 2288681 561 - - - - - --- - -11 -11 pyrazinamide (PZA) 25336456 HC_PhyResSE 2289252 2289252 SNP 1 t a intergenic Rv2043c pncA 2289241 2288681 561 - - - - - --- - -11 -11 pyrazinamide (PZA) 25336456 HC_PhyResSE 4247429 4247429 SNP 1 a g coding Rv3795 embB 4246514 4249810 3297 + Met 306 - Val Met306Val atg/gtg 916 916 ethambutol (EMB) 21300839 HC_PhyResSE 4247429 4247429 SNP 1 a c coding Rv3795 embB 4246514 4249810 3297 + Met 306 - Leu Met306Leu atg/ctg 916 916 ethambutol (EMB) 9257740 HC_PhyResSE 4247430 4247430 SNP 1 t c coding Rv3795 embB 4246514 4249810 3297 + Met 306 - Thr Met306Thr atg/acg 917 917 ethambutol (EMB) 11854934 HC_PhyResSE 4247431 4247431 SNP 1 g a coding Rv3795 embB 4246514 4249810 3297 + Met 306 - Ile Met306Ile atg/ata 918 918 ethambutol (EMB) 21300839 HC_PhyResSE 4247431 4247431 SNP 1 g c coding Rv3795 embB 4246514 4249810 3297 + Met 306 - Ile Met306Ile atg/atc 918 918 ethambutol (EMB) 21300839 HC_PhyResSE 4247431 4247431 SNP 1 g t coding Rv3795 embB 4246514 4249810 3297 + Met 306 - Ile Met306Ile atg/att 918 918 ethambutol (EMB) 21300839 HC_PhyResSE 4247729 4247729 SNP 1 g a coding Rv3795 embB 4246514 4249810 3297 + Gly 406 - Ser Gly406Ser ggc/agc 1216 1216 ethambutol (EMB) 20427375 HC_PhyResSE 4247729 4247729 SNP 1 g t coding Rv3795 embB 4246514 4249810 3297 + Gly 406 - Cys Gly406Cys ggc/tgc 1216 1216 ethambutol (EMB) 24055765 HC_PhyResSE 4247730 4247730 SNP 1 g c coding Rv3795 embB 4246514 4249810 3297 + Gly 406 - Ala Gly406Ala ggc/gcc 1217 1217 ethambutol (EMB) 20427375 HC_PhyResSE 4247730 4247730 SNP 1 g a coding Rv3795 embB 4246514 4249810 3297 + Gly 406 - Asp Gly406Asp ggc/gac 1217 1217 ethambutol (EMB) 20427375 HC_PhyResSE 4248003 4248003 SNP 1 a g coding Rv3795 embB 4246514 4249810 3297 + Gln 497 - Arg Gln497Arg cag/cgg 1490 1490 ethambutol (EMB) 20427375 HC_PhyResSE 6575 6575 SNP 1 c t coding Rv0005 gyrB 5240 7267 2028 + Arg 446 - Cys Arg446Cys cgt/tgt 1336 1336 fluoroquinolones (FQ) 19470506 LC_PhyResSE 6749 6749 SNP 1 g a coding Rv0005 gyrB 5240 7267 2028 + Ala 504 - Thr Ala504Thr gcg/acg 1510 1510 fluoroquinolones (FQ) 19470506 LC_PhyResSE 7566 7566 SNP 1 g a coding Rv0006 gyrA 7302 9818 2517 + Asp 89 - Asn Asp89Asn gac/aac 265 265 fluoroquinolones (FQ) 19687244 LC_PhyResSE 7582 7582 SNP 1 a t coding Rv0006 gyrA 7302 9818 2517 + Asp 94 - Val Asp94Val gac/gtc 281 281 fluoroquinolones (FQ) 17434825 LC_PhyResSE 575729 575729 SNP 1 c t coding Rv0486 mshA 575348 576790 1443 + Gln 128 - STOP Gln128STOP cag/tag 382 382 ethionamide (ETH) 18651841 LC_PhyResSE 576164 576164 SNP 1 c t coding Rv0486 mshA 575348 576790 1443 + Arg 273 - Cys Arg273Cys cgc/tgc 817 817 ethionamide (ETH) 18651841 LC_PhyResSE 576242 576242 SNP 1 g t coding Rv0486 mshA 575348 576790 1443 + Gly 299 - Cys Gly299Cys ggc/tgc 895 895 ethionamide (ETH) 18651841 LC_PhyResSE 576338 576338 SNP 1 c t coding Rv0486 mshA 575348 576790 1443 + Gln 331 - STOP Gln331STOP cag/tag 991 991 ethionamide (ETH) 18651841 LC_PhyResSE 576414 576414 SNP 1 g a coding Rv0486 mshA 575348 576790 1443 + Gly 356 - Asp Gly356Asp ggc/gac 1067 1067 ethionamide (ETH) 18651841 LC_PhyResSE 576429 576429 SNP 1 a c coding Rv0486 mshA 575348 576790 1443 + Glu 361 - Ala Glu361Ala gag/gcg 1082 1082 ethionamide (ETH) 18651841 LC_PhyResSE 761004 761004 SNP 1 a g coding Rv0667 rpoB 759807 763325 3519 + Thr 400 481 Ala Thr400Ala acc/gcc 1198 1198 rifampicin (RMP) 22646308 LC_PhyResSE 761093 761093 SNP 1 g c coding Rv0667 rpoB 759807 763325 3519 + Gln 429 510 His Gln429His cag/cac 1287 1287 rifampicin (RMP) 15184414 LC_PhyResSE 761095 761095 SNP 1 t c coding Rv0667 rpoB 759807 763325 3519 + Leu 430 511 Pro Leu430Pro ctg/ccg 1289 1289 rifampicin (RMP) 8027320 LC_PhyResSE 761095 761095 SNP 1 t g coding Rv0667 rpoB 759807 763325 3519 + Leu 430 511 Arg Leu430Arg ctg/cgg 1289 1289 rifampicin (RMP) 8027320 LC_PhyResSE 761098 761098 SNP 1 g t coding Rv0667 rpoB 759807 763325 3519 + Ser 431 512 Ile Ser431Ile agc/atc 1292 1292 rifampicin (RMP) 24055765 LC_PhyResSE 761098 761098 SNP 1 g c coding Rv0667 rpoB 759807 763325 3519 + Ser 431 512 Thr Ser431Thr agc/acc 1292 1292 rifampicin (RMP) 8027320 LC_PhyResSE 761100 761100 SNP 1 c a coding Rv0667 rpoB 759807 763325 3519 + Gln 432 513 Lys Gln432Lys caa/aaa 1294 1294 rifampicin (RMP) 11136757 LC_PhyResSE 761101 761101 SNP 1 a c coding Rv0667 rpoB 759807 763325 3519 + Gln 432 513 Pro Gln432Pro caa/cca 1295 1295 rifampicin (RMP) 9003625 LC_PhyResSE 761108 761108 SNP 1 g t coding Rv0667 rpoB 759807 763325 3519 + Met 434 515 Ile Met434Ile atg/att 1302 1302 rifampicin (RMP) 15184414 LC_PhyResSE 761111 761111 SNP 1 c g coding Rv0667 rpoB 759807 763325 3519 + Asp 435 516 Glu Asp435Glu gac/gag 1305 1305 rifampicin (RMP) 8027320 LC_PhyResSE 761117 761120 Del 3 caac c coding Rv0667 rpoB 759807 763325 3519 + Asn 438 519 - Asn438- aac/_ 1312 1314 rifampicin (RMP) 11136757 LC_PhyResSE 761120 761120 SNP 1 c g coding Rv0667 rpoB 759807 763325 3519 + Asn 438 519 Lys Asn438Lys aac/aag 1314 1314 rifampicin (RMP) 19721079 LC_PhyResSE 761128 761128 SNP 1 c t coding Rv0667 rpoB 759807 763325 3519 + Ser 441 522 Leu Ser441Leu tcg/ttg 1322 1322 rifampicin (RMP) 7759399 LC_PhyResSE 761128 761128 SNP 1 c g coding Rv0667 rpoB 759807 763325 3519 + Ser 441 522 Trp Ser441Trp tcg/tgg 1322 1322 rifampicin (RMP) 15814606 LC_PhyResSE 761140 761140 SNP 1 a t coding Rv0667 rpoB 759807 763325 3519 + His 445 526 Leu His445Leu cac/ctc 1334 1334 rifampicin (RMP) 10921994 LC_PhyResSE 761141 761141 SNP 1 c a coding Rv0667 rpoB 759807 763325 3519 + His 445 526 Gln His445Gln cac/caa 1335 1335 rifampicin (RMP) 8027320 LC_PhyResSE 761154 761154 SNP 1 t g coding Rv0667 rpoB 759807 763325 3519 + Ser 450 531 Ala Ser450Ala tcg/gcg 1348 1348 rifampicin (RMP) 11136757 LC_PhyResSE 781821 781821 SNP 1 a c coding Rv0682 rpsL 781560 781934 375 + Lys 88 - Gln Lys88Gln aag/cag 262 262 streptomycin (SM) 8849220 LC_PhyResSE 801268 801268 SNP 1 t c coding Rv0701 rplC 800809 801462 654 + Cys 154 - Arg Cys154Arg tgt/cgt 460 460 linezolid (LZD) 22371899 LC_PhyResSE 1472358 1472358 SNP 1 c t ribosomal MTB000019 rrs 1471846 1473382 1537 + - - - - --- - 513 513 streptomycin (SM) 7540819 LC_PhyResSE 1472359 1472359 SNP 1 a c ribosomal MTB000019 rrs 1471846 1473382 1537 + - - - - --- - 514 514 streptomycin (SM) 9160326 LC_PhyResSE 1472362 1472362 SNP 1 c t ribosomal MTB000019 rrs 1471846 1473382 1537 + - - - - --- - 517 517 streptomycin (SM) 9160326 LC_PhyResSE 1472750 1472750 SNP 1 c a ribosomal MTB000019 rrs 1471846 1473382 1537 + - - - - --- - 905 905 streptomycin (SM) 7540819 LC_PhyResSE 1472751 1472751 SNP 1 a g ribosomal MTB000019 rrs 1471846 1473382 1537 + - - - - --- - 906 906 streptomycin (SM) 9160326 LC_PhyResSE 1472752 1472752 SNP 1 a t ribosomal MTB000019 rrs 1471846 1473382 1537 + - - - - --- - 907 907 streptomycin (SM) 9160326 LC_PhyResSE 1475956 1475956 SNP 1 g t ribosomal MTB000020 rrl 1473658 1476795 3138 + - - - - --- - 2299 2299 linezolid (LZD) 18070973 LC_PhyResSE 1476471 1476471 SNP 1 g t ribosomal MTB000020 rrl 1473658 1476795 3138 + - - - - --- - 2814 2814 linezolid (LZD) 18070973 LC_PhyResSE 1673423 1673423 SNP 1 g t intergenic Rv1483 fabG1 1673440 1674183 744 + - - - - --- - -17 -17 isoniazid (INH) 14638486 LC_PhyResSE 1673424 1673424 SNP 1 a g intergenic Rv1483 fabG1 1673440 1674183 744 + - - - - --- - -16 -16 isoniazid (INH) 19494067 LC_PhyResSE 1674782 1674782 SNP 1 t c coding Rv1484 inhA 1674202 1675011 810 + Ile 194 - Thr Ile194Thr atc/acc 581 581 isoniazid (INH) ethionamide (ETH) 21110864 LC_PhyResSE 1833909 1833909 SNP 1 a c coding Rv1630 rpsA 1833542 1834987 1446 + Asp 123 - Ala Asp123Ala gac/gcc 368 368 pyrazinamide (PZA) 21835980 LC_PhyResSE 1834325 1834325 SNP 1 g a coding Rv1630 rpsA 1833542 1834987 1446 + Val 262 - Met Val262Met gtg/atg 784 784 pyrazinamide (PZA) 21835980 LC_PhyResSE 1834852 1834855 Del 3 cgcc c coding Rv1630 rpsA 1833542 1834987 1446 + Ala 438 - - Ala438- gcc/_ 1312 1314 pyrazinamide (PZA) 21835980 LC_PhyResSE 1917946 1917946 SNP 1 c t coding Rv1694 tlyA 1917940 1918746 807 + Arg 3 - STOP Arg3STOP cga/tga 7 7 capreomycin (CPR) 15673735 LC_PhyResSE 1917979 1917979 SNP 1 c t coding Rv1694 tlyA 1917940 1918746 807 + Arg 14 - Trp Arg14Trp cgg/tgg 40 40 capreomycin (CPR) 15673735 LC_PhyResSE 1917991 1917991 SNP 1 c t coding Rv1694 tlyA 1917940 1918746 807 + Arg 18 - STOP Arg18STOP cga/tga 52 52 capreomycin (CPR) 15673735 LC_PhyResSE 1918003 1918003 SNP 1 c t coding Rv1694 tlyA 1917940 1918746 807 + Gln 22 - STOP Gln22STOP cag/tag 64 64 capreomycin (CPR) 15673735 LC_PhyResSE 1918139 1918139 SNP 1 c a coding Rv1694 tlyA 1917940 1918746 807 + Ala 67 - Glu Ala67Glu gcg/gag 200 200 capreomycin (CPR) 15673735 LC_PhyResSE 1918144 1918144 SNP 1 a g coding Rv1694 tlyA 1917940 1918746 807 + Lys 69 - Glu Lys69Glu aaa/gaa 205 205 capreomycin (CPR) 15673735 LC_PhyResSE 1918211 1918211 SNP 1 c a coding Rv1694 tlyA 1917940 1918746 807 + Ala 91 - Glu Ala91Glu gca/gaa 272 272 capreomycin (CPR) 15673735 LC_PhyResSE 1918292 1918292 SNP 1 t c coding Rv1694 tlyA 1917940 1918746 807 + Leu 118 - Pro Leu118Pro ctg/ccg 353 353 capreomycin (CPR) 15673735 LC_PhyResSE 1918322 1918322 SNP 1 t a coding Rv1694 tlyA 1917940 1918746 807 + Val 128 - Glu Val128Glu gtg/gag 383 383 capreomycin (CPR) 15673735 LC_PhyResSE 1918388 1918388 SNP 1 t c coding Rv1694 tlyA 1917940 1918746 807 + Leu 150 - Pro Leu150Pro ctg/ccg 449 449 capreomycin (CPR) 15673735 LC_PhyResSE 1918487 1918487 SNP 1 c t coding Rv1694 tlyA 1917940 1918746 807 + Pro 183 - Leu Pro183Leu ccg/ctg 548 548 capreomycin (CPR) 15673735 LC_PhyResSE 1918489 1918489 SNP 1 c a coding Rv1694 tlyA 1917940 1918746 807 + Gln 184 - Lys Gln184Lys cag/aag 550 550 capreomycin (CPR) 15673735 LC_PhyResSE 1918489 1918489 SNP 1 c t coding Rv1694 tlyA 1917940 1918746 807 + Gln 184 - STOP Gln184STOP cag/tag 550 550 capreomycin (CPR) 15673735 LC_PhyResSE 1918494 1918494 SNP 1 t g coding Rv1694 tlyA 1917940 1918746 807 + Phe 185 - Leu Phe185Leu ttt/ttg 555 555 capreomycin (CPR) 15673735 LC_PhyResSE 1918651 1918651 SNP 1 g a coding Rv1694 tlyA 1917940 1918746 807 + Glu 238 - Lys Glu238Lys gag/aag 712 712 capreomycin (CPR) 15673735 LC_PhyResSE 2102240 2102240 SNP 1 c t coding Rv1854c ndh 2103042 2101651 1392 - Arg 268 - His Arg268His cgc/cac 803 803 isoniazid (INH) ethionamide (ETH) 11408244 LC_PhyResSE 2102715 2102715 SNP 1 t c coding Rv1854c ndh 2103042 2101651 1392 - Thr 110 - Ala Thr110Ala acc/gcc 328 328 isoniazid (INH) ethionamide (ETH) 11408244 LC_PhyResSE 2155167 2155167 SNP 1 g c coding Rv1908c katG 2156111 2153889 2223 - Ser 315 - Arg Ser315Arg agc/agg 945 945 isoniazid (INH) 16870753 LC_PhyResSE 2155167 2155167 SNP 1 g t coding Rv1908c katG 2156111 2153889 2223 - Ser 315 - Arg Ser315Arg agc/aga 945 945 isoniazid (INH) 17403134 LC_PhyResSE 2155206 2155206 SNP 1 g c coding Rv1908c katG 2156111 2153889 2223 - Ser 302 - Arg Ser302Arg agc/agg 906 906 isoniazid (INH) 22646308 LC_PhyResSE 2155212 2155212 SNP 1 c g coding Rv1908c katG 2156111 2153889 2223 - Trp 300 - Cys Trp300Cys tgg/tgc 900 900 isoniazid (INH) 22646308 LC_PhyResSE 2155222 2155222 SNP 1 c a coding Rv1908c katG 2156111 2153889 2223 - Gly 297 - Val Gly297Val ggc/gtc 890 890 isoniazid (INH) 11796356 LC_PhyResSE 2155699 2155699 SNP 1 t c coding Rv1908c katG 2156111 2153889 2223 - Asn 138 - Ser Asn138Ser aac/agc 413 413 isoniazid (INH) 16870753 LC_PhyResSE 2288704 2288704 SNP 1 c a coding Rv2043c pncA 2289241 2288681 561 - Val 180 - Phe Val180Phe gtc/ttc 538 538 pyrazinamide (PZA) 11641519 LC_PhyResSE 2288727 2288727 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Leu 172 - Pro Leu172Pro ctg/ccg 515 515 pyrazinamide (PZA) 22646308 LC_PhyResSE 2288730 2288730 SNP 1 g a coding Rv2043c pncA 2289241 2288681 561 - Ala 171 - Val Ala171Val gcg/gtg 512 512 pyrazinamide (PZA) 10471589 LC_PhyResSE 2288757 2288757 SNP 1 c t coding Rv2043c pncA 2289241 2288681 561 - Gly 162 - Asp Gly162Asp ggt/gat 485 485 pyrazinamide (PZA) 22646308 LC_PhyResSE 2288766 2288766 SNP 1 a c coding Rv2043c pncA 2289241 2288681 561 - Leu 159 - Arg Leu159Arg ctg/cgg 476 476 pyrazinamide (PZA) 11641519 LC_PhyResSE 2288782 2288782 SNP 1 t c coding Rv2043c pncA 2289241 2288681 561 - Arg 154 - Gly Arg154Gly agg/ggg 460 460 pyrazinamide (PZA) 21300839 LC_PhyResSE 2288805 2288805 SNP 1 g t coding Rv2043c pncA 2289241 2288681 561 - Ala 146 - Glu Ala146Glu gcg/gag 437 437 pyrazinamide (PZA) 22646308 LC_PhyResSE 2288806 2288806 SNP 1 c t coding Rv2043c pncA 2289241 2288681 561 - Ala 146 - Thr Ala146Thr gcg/acg 436 436 pyrazinamide (PZA) 11641519 LC_PhyResSE 2288820 2288820 SNP 1 t g coding Rv2043c pncA 2289241 2288681 561 - Gln 141 - Pro Gln141Pro cag/ccg 422 422 pyrazinamide (PZA) 8640557 LC_PhyResSE 2288821 2288821 SNP 1 g a coding Rv2043c pncA 2289241 2288681 561 - Gln 141 - STOP Gln141STOP cag/tag 421 421 pyrazinamide (PZA) 11641519 LC_PhyResSE 2288836 2288836 SNP 1 c t coding Rv2043c pncA 2289241 2288681 561 - Asp 136 - Asn Asp136Asn gat/aat 406 406 pyrazinamide (PZA) 11641519 LC_PhyResSE 2288836 2288836 SNP 1 c a coding Rv2043c pncA 2289241 2288681 561 - Asp 136 - Tyr Asp136Tyr gat/tat 406 406 pyrazinamide (PZA) 11641519 LC_PhyResSE 2288844 2288844 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Ile 133 - Thr Ile133Thr att/act 398 398 pyrazinamide (PZA) 10390239 LC_PhyResSE 2288848 2288848 SNP 1 c t coding Rv2043c pncA 2289241 2288681 561 - Gly 132 - Ser Gly132Ser ggt/agt 394 394 pyrazinamide (PZA) 9055989 LC_PhyResSE 2288859 2288859 SNP 1 a c coding Rv2043c pncA 2289241 2288681 561 - Val 128 - Gly Val128Gly gtc/ggc 383 383 pyrazinamide (PZA) 15616332 LC_PhyResSE 2288883 2288883 SNP 1 a c coding Rv2043c pncA 2289241 2288681 561 - Leu 120 - Arg Leu120Arg ctg/cgg 359 359 pyrazinamide (PZA) 21300839 LC_PhyResSE 2288885 2288885 SNP 1 c t coding Rv2043c pncA 2289241 2288681 561 - Trp 119 - STOP Trp119STOP tgg/tga 357 357 pyrazinamide (PZA) 11641519 LC_PhyResSE 2288902 2288902 SNP 1 t g coding Rv2043c pncA 2289241 2288681 561 - Thr 114 - Pro Thr114Pro acg/ccg 340 340 pyrazinamide (PZA) 9692180 LC_PhyResSE 2288934 2288934 SNP 1 t g coding Rv2043c pncA 2289241 2288681 561 - Tyr 103 - Ser Tyr103Ser tac/tcc 308 308 pyrazinamide (PZA) 11641519 LC_PhyResSE 2288953 2288953 SNP 1 c t coding Rv2043c pncA 2289241 2288681 561 - Gly 97 - Ser Gly97Ser ggt/agt 289 289 pyrazinamide (PZA) 10681313 LC_PhyResSE 2288956 2288956 SNP 1 t c coding Rv2043c pncA 2289241 2288681 561 - Lys 96 - Glu Lys96Glu aag/gag 286 286 pyrazinamide (PZA) 22646308 LC_PhyResSE 2288982 2288982 SNP 1 g a coding Rv2043c pncA 2289241 2288681 561 - Thr 87 - Met Thr87Met acg/atg 260 260 pyrazinamide (PZA) 10390238 LC_PhyResSE 2288988 2288988 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Leu 85 - Pro Leu85Pro ctg/ccg 254 254 pyrazinamide (PZA) 9055989 LC_PhyResSE 2289016 2289016 SNP 1 t g coding Rv2043c pncA 2289241 2288681 561 - Thr 76 - Pro Thr76Pro act/cct 226 226 pyrazinamide (PZA) 9056006 LC_PhyResSE 2289031 2289031 SNP 1 g a coding Rv2043c pncA 2289241 2288681 561 - His 71 - Tyr His71Tyr cat/tat 211 211 pyrazinamide (PZA) 16848344 LC_PhyResSE 2289036 2289036 SNP 1 g a coding Rv2043c pncA 2289241 2288681 561 - Pro 69 - Leu Pro69Leu cca/cta 206 206 pyrazinamide (PZA) 10390238 LC_PhyResSE 2289039 2289039 SNP 1 c g coding Rv2043c pncA 2289241 2288681 561 - Trp 68 - Ser Trp68Ser tgg/tcg 203 203 pyrazinamide (PZA) 11641519 LC_PhyResSE 2289040 2289040 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Trp 68 - Arg Trp68Arg tgg/cgg 202 202 pyrazinamide (PZA) 11641519 LC_PhyResSE 2289040 2289040 SNP 1 a c coding Rv2043c pncA 2289241 2288681 561 - Trp 68 - Gly Trp68Gly tgg/ggg 202 202 pyrazinamide (PZA) 11641519 LC_PhyResSE 2289049 - Ins 1 t coding Rv2043c pncA 2289241 2288681 561 - Ser 65 - - Ser65- tcc/atcc 193 193 pyrazinamide (PZA) 22646308 LC_PhyResSE 2289052 2289052 SNP 1 a c coding Rv2043c pncA 2289241 2288681 561 - Tyr 64 - Asp Tyr64Asp tat/gat 190 190 pyrazinamide (PZA) 11641519 LC_PhyResSE 2289054 2289054 SNP 1 t c coding Rv2043c pncA 2289241 2288681 561 - Asp 63 - Gly Asp63Gly gac/ggc 188 188 pyrazinamide (PZA) 9692180 LC_PhyResSE 2289061 2289061 SNP 1 t g coding Rv2043c pncA 2289241 2288681 561 - Thr 61 - Pro Thr61Pro aca/cca 181 181 pyrazinamide (PZA) 10390238 LC_PhyResSE 2289073 2289073 SNP 1 g c coding Rv2043c pncA 2289241 2288681 561 - His 57 - Asp His57Asp cac/gac 169 169 pyrazinamide (PZA) 19861002 LC_PhyResSE 2289073 2289073 SNP 1 g a coding Rv2043c pncA 2289241 2288681 561 - His 57 - Tyr His57Tyr cac/tac 169 169 pyrazinamide (PZA) 16848344 LC_PhyResSE 2289081 2289081 SNP 1 g a coding Rv2043c pncA 2289241 2288681 561 - Pro 54 - Leu Pro54Leu ccg/ctg 161 161 pyrazinamide (PZA) 16848344 LC_PhyResSE 2289096 2289096 SNP 1 t g coding Rv2043c pncA 2289241 2288681 561 - Asp 49 - Ala Asp49Ala gac/gcc 146 146 pyrazinamide (PZA) 11641519 LC_PhyResSE 2289096 2289096 SNP 1 t c coding Rv2043c pncA 2289241 2288681 561 - Asp 49 - Gly Asp49Gly gac/ggc 146 146 pyrazinamide (PZA) 10390239 LC_PhyResSE 2289103 2289103 SNP 1 t c coding Rv2043c pncA 2289241 2288681 561 - Thr 47 - Ala Thr47Ala acc/gcc 139 139 pyrazinamide (PZA) 22646308 LC_PhyResSE 2289108 2289108 SNP 1 a c coding Rv2043c pncA 2289241 2288681 561 - Val 45 - Gly Val45Gly gtg/ggg 134 134 pyrazinamide (PZA) 11641519 LC_PhyResSE 2289159 2289159 SNP 1 g t coding Rv2043c pncA 2289241 2288681 561 - Ala 28 - Asp Ala28Asp gcc/gac 83 83 pyrazinamide (PZA) 11641519 LC_PhyResSE 2289201 2289201 SNP 1 c t coding Rv2043c pncA 2289241 2288681 561 - Cys 14 - Tyr Cys14Tyr tgc/tac 41 41 pyrazinamide (PZA) 11641519 LC_PhyResSE 2289204 2289204 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Phe 13 - Ser Phe13Ser ttc/tcc 38 38 pyrazinamide (PZA) 10390238 LC_PhyResSE 2289208 2289208 SNP 1 c t coding Rv2043c pncA 2289241 2288681 561 - Asp 12 - Asn Asp12Asn gac/aac 34 34 pyrazinamide (PZA) 9055989 LC_PhyResSE 2289213 2289213 SNP 1 t c coding Rv2043c pncA 2289241 2288681 561 - Gln 10 - Arg Gln10Arg cag/cgg 29 29 pyrazinamide (PZA) 10681313 LC_PhyResSE 2289213 2289213 SNP 1 t g coding Rv2043c pncA 2289241 2288681 561 - Gln 10 - Pro Gln10Pro cag/ccg 29 29 pyrazinamide (PZA) 21300839 LC_PhyResSE 2289216 2289216 SNP 1 a g coding Rv2043c pncA 2289241 2288681 561 - Val 9 - Ala Val9Ala gtg/gcg 26 26 pyrazinamide (PZA) 11641519 LC_PhyResSE 2289216 2289216 SNP 1 a c coding Rv2043c pncA 2289241 2288681 561 - Val 9 - Gly Val9Gly gtg/ggg 26 26 pyrazinamide (PZA) 11641519 LC_PhyResSE 2289219 2289219 SNP 1 t c coding Rv2043c pncA 2289241 2288681 561 - Asp 8 - Gly Asp8Gly gac/ggc 23 23 pyrazinamide (PZA) 11641519 LC_PhyResSE 2289222 2289222 SNP 1 a t coding Rv2043c pncA 2289241 2288681 561 - Val 7 - Asp Val7Asp gtc/gac 20 20 pyrazinamide (PZA) 11641519 LC_PhyResSE 2289226 - Ins 1 a coding Rv2043c pncA 2289241 2288681 561 - Ile 6 - - Ile6- atc/catc 16 16 pyrazinamide (PZA) 22646308 LC_PhyResSE 2289231 2289231 SNP 1 a c coding Rv2043c pncA 2289241 2288681 561 - Leu 4 - Trp Leu4Trp ttg/tgg 11 11 pyrazinamide (PZA) 11641519 LC_PhyResSE 2289235 2289235 SNP 1 c g coding Rv2043c pncA 2289241 2288681 561 - Ala 3 - Pro Ala3Pro gcg/ccg 7 7 pyrazinamide (PZA) 10390238 LC_PhyResSE 2289239 2289239 SNP 1 c a coding Rv2043c pncA 2289241 2288681 561 - Met 1 - Ile Met1Ile atg/att 3 3 pyrazinamide (PZA) 11641519 LC_PhyResSE 2715342 2715342 SNP 1 c t intergenic Rv2416c eis 2715332 2714124 1209 - - - - - --- - -10 -10 kanamycin (KAN) 21300839 LC_PhyResSE 2715346 2715346 SNP 1 g a intergenic Rv2416c eis 2715332 2714124 1209 - - - - - --- - -14 -14 kanamycin (KAN) 21300839 LC_PhyResSE 2726136 2726136 SNP 1 c t intergenic Rv2428 ahpC 2726193 2726780 588 + - - - - --- - -57 -57 isoniazid (INH) 22646308 LC_PhyResSE 2726145 2726145 SNP 1 g a intergenic Rv2428 ahpC 2726193 2726780 588 + - - - - --- - -48 -48 isoniazid (INH) 12654653 LC_PhyResSE 3073808 3073808 SNP 1 g c coding Rv2764c thyA 3074471 3073680 792 - Arg 222 - Gly Arg222Gly cgc/ggc 664 664 para-aminosalicylic acid (PAS) 15225321 LC_PhyResSE 4241078 4241078 SNP 1 a g coding Rv3793 embC 4239863 4243147 3285 + Ile 406 - Val Ile406Val atc/gtc 1216 1216 ethambutol (EMB) 20427375 LC_PhyResSE 4243221 4243221 SNP 1 c t intergenic Rv3794 embA 4243233 4246517 3285 + - - - - --- - -12 -12 ethambutol (EMB) 20427375 LC_PhyResSE 4243225 4243225 SNP 1 c a intergenic Rv3794 embA 4243233 4246517 3285 + - - - - --- - -8 -8 ethambutol (EMB) 20427375 LC_PhyResSE 4243242 4243242 SNP 1 g a coding Rv3794 embA 4243233 4246517 3285 + Asp 4 - Asn Asp4Asn gac/aac 10 10 ethambutol (EMB) 10639358 LC_PhyResSE 4243245 4243245 SNP 1 g a coding Rv3794 embA 4243233 4246517 3285 + Gly 5 - Ser Gly5Ser ggt/agt 13 13 ethambutol (EMB) 10639358 LC_PhyResSE 4243833 4243833 SNP 1 g a coding Rv3794 embA 4243233 4246517 3285 + Ala 201 - Thr Ala201Thr gcg/acg 601 601 ethambutol (EMB) 10639358 LC_PhyResSE 4244193 4244193 SNP 1 g a coding Rv3794 embA 4243233 4246517 3285 + Gly 321 - Ser Gly321Ser ggc/agc 961 961 ethambutol (EMB) 10639358 LC_PhyResSE 4244281 4244281 SNP 1 g a coding Rv3794 embA 4243233 4246517 3285 + Gly 350 - Asp Gly350Asp ggc/gac 1049 1049 ethambutol (EMB) 10639358 LC_PhyResSE 4244617 4244617 SNP 1 c t coding Rv3794 embA 4243233 4246517 3285 + Ala 462 - Val Ala462Val gcg/gtg 1385 1385 ethambutol (EMB) 10639358 LC_PhyResSE 4245730 4245730 SNP 1 a c coding Rv3794 embA 4243233 4246517 3285 + Asp 833 - Ala Asp833Ala gac/gcc 2498 2498 ethambutol (EMB) 10639358 LC_PhyResSE 4246734 4246734 SNP 1 t g coding Rv3795 embB 4246514 4249810 3297 + Leu 74 - Arg Leu74Arg ctg/cgg 221 221 ethambutol (EMB) 20427375 LC_PhyResSE 4247402 4247402 SNP 1 t g coding Rv3795 embB 4246514 4249810 3297 + Ser 297 - Ala Ser297Ala tcg/gcg 889 889 ethambutol (EMB) 10639358 LC_PhyResSE 4247469 4247469 SNP 1 a c coding Rv3795 embB 4246514 4249810 3297 + Tyr 319 - Ser Tyr319Ser tat/tct 956 956 ethambutol (EMB) 16641474 LC_PhyResSE 4247495 4247495 SNP 1 g t coding Rv3795 embB 4246514 4249810 3297 + Asp 328 - Tyr Asp328Tyr gat/tat 982 982 ethambutol (EMB) 10639358 LC_PhyResSE 4247496 4247496 SNP 1 a g coding Rv3795 embB 4246514 4249810 3297 + Asp 328 - Gly Asp328Gly gat/ggt 983 983 ethambutol (EMB) 10639358 LC_PhyResSE 4247507 4247507 SNP 1 t c coding Rv3795 embB 4246514 4249810 3297 + Trp 332 - Arg Trp332Arg tgg/cgg 994 994 ethambutol (EMB) 22646308 LC_PhyResSE 4247513 4247513 SNP 1 t c coding Rv3795 embB 4246514 4249810 3297 + Tyr 334 - His Tyr334His tac/cac 1000 1000 ethambutol (EMB) 16641474 LC_PhyResSE 4247573 4247573 SNP 1 g a coding Rv3795 embB 4246514 4249810 3297 + Asp 354 - Asn Asp354Asn gac/aac 1060 1060 ethambutol (EMB) 20427375 LC_PhyResSE 4247717 4247717 SNP 1 c g coding Rv3795 embB 4246514 4249810 3297 + Leu 402 - Val Leu402Val ctg/gtg 1204 1204 ethambutol (EMB) 20427375 LC_PhyResSE 4247723 4247723 SNP 1 c t coding Rv3795 embB 4246514 4249810 3297 + Pro 404 - Ser Pro404Ser ccg/tcg 1210 1210 ethambutol (EMB) 20427375 LC_PhyResSE 4247863 4247863 SNP 1 c g coding Rv3795 embB 4246514 4249810 3297 + Ile 450 - Met Ile450Met atc/atg 1350 1350 ethambutol (EMB) 20427375 LC_PhyResSE 4247873 4247873 SNP 1 g a coding Rv3795 embB 4246514 4249810 3297 + Ala 454 - Thr Ala454Thr gcg/acg 1360 1360 ethambutol (EMB) 20427375 LC_PhyResSE 4248002 4248002 SNP 1 c a coding Rv3795 embB 4246514 4249810 3297 + Gln 497 - Lys Gln497Lys cag/aag 1489 1489 ethambutol (EMB) 20427375 LC_PhyResSE 4248747 4248747 SNP 1 g a coding Rv3795 embB 4246514 4249810 3297 + Gly 745 - Asp Gly745Asp ggc/gac 2234 2234 ethambutol (EMB) 10639358 LC_PhyResSE 4249518 4249518 SNP 1 a g coding Rv3795 embB 4246514 4249810 3297 + His 1002 - Arg His1002Arg cac/cgc 3005 3005 ethambutol (EMB) 22646308 LC_PhyResSE 4326087 4326087 SNP 1 g t coding Rv3854c ethA 4327473 4326004 1470 - Arg 463 - Ser Arg463Ser cgt/agt 1387 1387 ethionamide (ETH) 14638486 LC_PhyResSE 4326236 4326236 SNP 1 c t coding Rv3854c ethA 4327473 4326004 1470 - Gly 413 - Asp Gly413Asp ggt/gat 1238 1238 ethionamide (ETH) 14638486 LC_PhyResSE 4326300 4326300 SNP 1 t c coding Rv3854c ethA 4327473 4326004 1470 - Thr 392 - Ala Thr392Ala acg/gcg 1174 1174 ethionamide (ETH) 14638486 LC_PhyResSE 4326320 4326320 SNP 1 c t coding Rv3854c ethA 4327473 4326004 1470 - Gly 385 - Asp Gly385Asp ggc/gac 1154 1154 ethionamide (ETH) 14638486 LC_PhyResSE 4326333 4326333 SNP 1 c g coding Rv3854c ethA 4327473 4326004 1470 - Ala 381 - Pro Ala381Pro gcc/ccc 1141 1141 ethionamide (ETH) 10944230 LC_PhyResSE 4326449 4326449 SNP 1 g t coding Rv3854c ethA 4327473 4326004 1470 - Thr 342 - Lys Thr342Lys acg/aag 1025 1025 ethionamide (ETH) 10944230 LC_PhyResSE 4326461 4326461 SNP 1 a c coding Rv3854c ethA 4327473 4326004 1470 - Ile 338 - Ser Ile338Ser atc/agc 1013 1013 ethionamide (ETH) 14638486 LC_PhyResSE 4326738 4326738 SNP 1 g a coding Rv3854c ethA 4327473 4326004 1470 - Gln 246 - STOP Gln246STOP cag/tag 736 736 ethionamide (ETH) 14638486 LC_PhyResSE 4326807 4326807 SNP 1 c t coding Rv3854c ethA 4327473 4326004 1470 - Glu 223 - Lys Glu223Lys gag/aag 667 667 ethionamide (ETH) 14638486 LC_PhyResSE 4326917 4326917 SNP 1 g t coding Rv3854c ethA 4327473 4326004 1470 - Thr 186 - Lys Thr186Lys acg/aag 557 557 ethionamide (ETH) 10944230 LC_PhyResSE 4327224 4327224 SNP 1 a c coding Rv3854c ethA 4327473 4326004 1470 - Tyr 84 - Asp Tyr84Asp tac/gac 250 250 ethionamide (ETH) 10944230 LC_PhyResSE 4327301 4327301 SNP 1 t g coding Rv3854c ethA 4327473 4326004 1470 - Asp 58 - Ala Asp58Ala gac/gcc 173 173 ethionamide (ETH) 10944230 LC_PhyResSE 4327307 4327307 SNP 1 t g coding Rv3854c ethA 4327473 4326004 1470 - Asp 56 - Ala Asp56Ala gac/gcc 167 167 ethionamide (ETH) 14638486 LC_PhyResSE 4327322 4327322 SNP 1 g a coding Rv3854c ethA 4327473 4326004 1470 - Pro 51 - Leu Pro51Leu ccc/ctc 152 152 ethionamide (ETH) 10944230 LC_PhyResSE 4327346 4327346 SNP 1 c t coding Rv3854c ethA 4327473 4326004 1470 - Gly 43 - Asp Gly43Asp ggc/gac 128 128 ethionamide (ETH) 14638486 LC_PhyResSE 4327347 4327347 SNP 1 c a coding Rv3854c ethA 4327473 4326004 1470 - Gly 43 - Cys Gly43Cys ggc/tgc 127 127 ethionamide (ETH) 10944230 LC_PhyResSE 4407604 4407604 SNP 1 g t coding Rv3919c gidB 4408202 4407528 675 - Ala 200 - Glu Ala200Glu gcg/gag 599 599 streptomycin (SM) 22646308 LC_PhyResSE 4407790 4407790 SNP 1 g a coding Rv3919c gidB 4408202 4407528 675 - Ala 138 - Val Ala138Val gcg/gtg 413 413 streptomycin (SM) 22646308 LC_PhyResSE 4407824 4407824 SNP 1 g a coding Rv3919c gidB 4408202 4407528 675 - Gln 127 - STOP Gln127STOP caa/taa 379 379 streptomycin (SM) 22646308 LC_PhyResSE 4407931 4407931 SNP 1 a g coding Rv3919c gidB 4408202 4407528 675 - Leu 91 - Pro Leu91Pro cta/cca 272 272 streptomycin (SM) 22646308 LC_PhyResSE 4407940 4407940 SNP 1 a g coding Rv3919c gidB 4408202 4407528 675 - Val 88 - Ala Val88Ala gta/gca 263 263 streptomycin (SM) 22646308 LC_PhyResSE 4407992 4407992 SNP 1 c t coding Rv3919c gidB 4408202 4407528 675 - Gly 71 - Arg Gly71Arg gga/aga 211 211 streptomycin (SM) 22646308 LC_PhyResSE 4408009 4408009 SNP 1 a c coding Rv3919c gidB 4408202 4407528 675 - Val 65 - Gly Val65Gly gtc/ggc 194 194 streptomycin (SM) 22646308 LC_PhyResSE 4408102 4408102 SNP 1 c g coding Rv3919c gidB 4408202 4407528 675 - Gly 34 - Ala Gly34Ala ggg/gcg 101 101 streptomycin (SM) 22646308 LC_PhyResSE