Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR GOTERM_MF_DIRECT,GO:0005509~calcium ion binding,44,9.67032967,2.70E-09,"RYR2, TENM2, DHH, PCDH11X, STAB2, PKD2L1, C2CD4C, PCDH19, CDH7, ADGRE1, TRPM2, PPP3R2, MMP27, ME1, OIT3, TBC1D8B, TPD52, SYT3, PLA2G12B, JAG1, MMP1, PKDREJ, PCDHB12, TC2N, SYTL5, NPNT, EML1, SYT8, MMP10, SYTL2, NELL2, CPS1, MMP16, MYL2, PLSCR4, S100A5, FKBP9, EFHC2, PLCB1, PPEF2, DNASE1L3, DSC3, MATN2, ADGRL3",374,717,16881,2.769874477,1.42E-06,1.42E-06,1.42E-06 GOTERM_CC_DIRECT,GO:0005887~integral component of plasma membrane,66,14.50549451,2.25E-08,"TENM1, GABRB1, TENM2, PCDH11X, CHRM5, MPL, STAB2, AQP6, PTPRM, ADRA1B, FCAR, GRM1, ADGRE1, GJA1, CYSLTR1, CCKAR, BOC, GPR171, FFAR4, BDKRB1, FFAR1, MRGPRX4, NEO1, CD34, TRPC5, SEMA6A, UGT1A1, SLC2A10, PTH2R, HTR3B, ADCY9, MMP16, CCKBR, CEACAM4, TYRO3, B3GNT3, PRKD1, TLR3, CX3CR1, GYPE, CD1A, SLC7A3, EFNB1, TRPM2, CD19, ADAM23, SLC17A2, RHBG, SLC17A3, MPP3, JAG1, CD72, SLC12A5, KCNJ11, P2RY14, FZD6, GPR55, PCDHB12, CALHM3, GP9, SLC6A8, CD40LG, CNTN2, CSPG4, LGR4, ADGRL3",410,1415,18224,2.073229337,6.54E-06,6.54E-06,6.45E-06 GOTERM_CC_DIRECT,GO:0005578~proteinaceous extracellular matrix,21,4.615384615,2.94E-06,"COL26A1, WNT10A, COL15A1, MMP1, OMD, NPNT, ADAMTS10, WISP1, HAPLN1, MMP10, ADAMTSL5, MMP16, LOX, CHL1, EPYC, ANOS1, COL4A5, TGFBI, CTHRC1, MATN2, TECTA",410,268,18224,3.482926829,8.55E-04,4.28E-04,4.22E-04 GOTERM_CC_DIRECT,GO:0005886~plasma membrane,131,28.79120879,1.00E-05,"RAB3B, CHRM5, PCDH11X, MPL, PKD2L1, GPR62, RXFP1, CDH7, LAMP5, CYSLTR1, GJA1, BAIAP2L2, FRRS1L, PLAU, GRB10, ENPP6, CA14, TECTA, ENTPD2, CD300A, MTUS1, OR2L2, ANK3, TC2N, SYTL5, SYTL2, ADCY9, ANOS1, PRKD1, DSC3, ABCB1, DHH, GYPE, OR2K2, C2CD4C, PCDH19, NALCN, CD1A, ADGRG3, NKAIN2, TRPM2, EFNB1, DPP6, KCNV2, NKAIN3, CD19, KCNN2, TAC1, FZD1, ATP8B4, SYT3, CARMIL3, JAG1, FZD2, ABCA3, FZD6, FZD9, CYBRD1, SYT8, GP9, RAET1E, SLC6A8, VNN1, FXYD2, CNTN2, KLRD1, TGFBI, HRG, GAPT, ACHE, RYR2, TENM1, GABRB1, DOCK4, TENM2, STAB2, SECTM1, ADRA1B, GRM1, FCAR, SMPD3, CCKAR, JPH3, CHL1, BOC, ME1, FFAR4, BDKRB1, TNFAIP8L3, FFAR1, NEO1, CD34, TAS2R4, TRPC5, SLC2A10, FGG, PTH2R, HTR3B, GFRA2, CCKBR, MMP16, CATSPERG, PLSCR4, LTA, RHOU, SMPDL3B, SHANK1, CX3CR1, AMER3, ASAP2, SLC7A3, CACNG8, ADAM23, CACNG1, RHBG, KCNJ1, SLC17A3, COL26A1, MCOLN3, SLC12A5, CD72, KCNJ11, P2RY14, GPR55, MCOLN2, LILRB4, FRAS1, FCGR2A, CD40LG, CD244, LGR4",410,4121,18224,1.412955652,0.00291554,9.73E-04,9.60E-04 GOTERM_BP_DIRECT,GO:0007155~cell adhesion,27,5.934065934,1.64E-05,"CX3CR1, ACHE, COL15A1, STAB2, WISP1, HAPLN1, ADGRE1, EFNB1, ISLR, PDZD2, IBSP, CHL1, BOC, ADAM23, CTNNA2, NEO1, CD34, CD72, CD300A, OMD, PCDHB12, GP9, TYRO3, ANOS1, CNTN2, TGFBI, DSC3",379,459,16792,2.60623933,0.028119729,0.028505996,0.028489566 GOTERM_CC_DIRECT,GO:0005576~extracellular region,63,13.84615385,1.81E-05,"ACHE, TENM1, CLU, CHRDL1, FCAR, HAPLN1, AADACL2, LIPF, FGF5, PRB4, ESM1, ISLR, ADAMTSL5, IBSP, PLAU, CTSL, ENPP6, FAM19A4, PLA2G12B, MUCL1, MMP1, FGG, OMD, RNASE6, NPNT, MMP10, LOX, ZPBP2, ANOS1, COL4A5, ANG, WFDC10B, DNASE1L3, DSC3, COL15A1, ITIH3, HTRA3, AOAH, NTS, PDZD2, ADAM23, TAC1, HCRT, COL26A1, WNT10A, CCL23, JAG1, ODAM, HIST1H4L, KLK13, MAPK15, NELL2, IGSF10, CXCL11, RAET1E, PTX3, CSPG4, TGFBI, HRG, IL17C, IL17A, C1QC, PF4",410,1610,18224,1.739300106,0.005250352,0.001316034,0.001297944 GOTERM_CC_DIRECT,GO:0016021~integral component of membrane,155,34.06593407,2.34E-05,"GALNT14, DENND5B, TMEM200A, PCDH11X, MPL, AQP6, PKD2L1, GPR62, RXFP1, CDH7, LAMP5, AADACL2, FRRS1L, GPR171, CA14, SLC25A47, SCARA3, ENTPD2, SEMA6A, CD300A, OR2L2, FRMD5, ADCY9, ASPHD1, TYRO3, IDO2, DSC3, ABCB1, GYPE, RNF180, TMEM59L, OR2K2, PCDH19, NALCN, CD1A, ADGRG3, NKAIN2, TRPM2, DPP6, KCNV2, NKAIN3, CD19, UGT3A1, KCNN2, FZD1, ANKRD29, ATP8B4, SYT3, SLC37A2, TMEM132E, JAG1, FZD2, ABCA6, ABCA3, TMEM190, FZD6, FZD9, CYBRD1, NSG1, CYP4F8, SYT8, OCLM, RAET1E, TMEM235, SLC6A8, GJB1, VNN1, FAM151A, GJB6, TMCC3, CSPG4, KLRD1, RNF183, GAPT, ACHE, RYR2, TENM1, ST6GALNAC1, GABRB1, MOGAT3, FAM69B, SLC35F4, PTPRM, SECTM1, HRCT1, GRM1, FCAR, SMPD3, ADGRE1, JPH3, CHL1, C3ORF52, FFAR4, BDKRB1, FFAR1, RNF150, MRGPRX4, CD34, GALNT9, TAS2R4, UGT1A1, SLC2A10, ELOVL2, PTH2R, KIAA1024, C1ORF162, HTR3B, SEZ6L, B3GNT9, CCKBR, PLSCR4, CEACAM4, B3GNT3, TLR3, CX3CR1, COL15A1, CLEC2L, TYRP1, LRP3, TMEM201, AWAT1, ADAM23, ANKAR, MARVELD3, MAL2, SLC17A2, RHBG, KCNJ1, SLC17A3, RPRM, MCOLN3, SLC12A5, CD72, KCNJ11, P2RY14, GPR55, LHFPL3, HS3ST5, PKDREJ, C14ORF132, OTOP2, LHFPL1, SGCZ, MCOLN2, LILRB4, NELL2, TSPO2, FRAS1, FCGR2A, CD40LG, SCD, CD244, LGR4, ADGRL2, ADGRL3",410,5163,18224,1.334410416,0.006785929,0.001361796,0.001343077 GOTERM_BP_DIRECT,GO:0007267~cell-cell signaling,17,3.736263736,2.17E-04,"FZD1, CCL23, TFAP2C, DHH, ADRA1B, WISP1, FGF5, EFNB1, CXCL11, GJA1, GJB1, LTA, PGR, TAC1, IL17C, CCL26, IL17A",379,254,16792,2.965366796,0.313549584,0.187981913,0.187873566 GOTERM_CC_DIRECT,GO:0031012~extracellular matrix,18,3.956043956,4.01E-04,"COL26A1, COL15A1, HIST1H4L, MMP1, TSHZ2, SSC5D, CLU, ADAMTS10, HAPLN1, MMP10, FRAS1, MMP27, ADAMTSL5, MMP16, IBSP, TGFBI, NES, MATN2",410,296,18224,2.702966381,0.11019771,0.019455428,0.019187999 GOTERM_BP_DIRECT,GO:0030574~collagen catabolic process,8,1.758241758,5.71E-04,"COL26A1, COL15A1, MMP27, MMP16, MMP1, CTSL, COL4A5, MMP10",379,64,16792,5.538258575,0.629006276,0.330238662,0.330048322 GOTERM_MF_DIRECT,GO:0005262~calcium channel activity,8,1.758241758,8.81E-04,"RYR2, TRPM2, MCOLN3, TRPC5, DENND5B, PKDREJ, PKD2L1, MCOLN2",374,70,16881,5.158441558,0.371113542,0.169246209,0.168924448 GOTERM_MF_DIRECT,GO:0030276~clathrin binding,7,1.538461538,9.65E-04,"SYT3, TRPC5, C2CD4C, SYTL5, TC2N, SYT8, SYTL2",374,52,16881,6.076048951,0.398292505,0.169246209,0.168924448 GOTERM_BP_DIRECT,GO:0017158~regulation of calcium ion-dependent exocytosis,6,1.318681319,0.001048015,"SYT3, C2CD4C, SYTL5, TC2N, SYT8, SYTL2",379,35,16792,7.595326046,0.838024175,0.454576536,0.454314532 GOTERM_BP_DIRECT,GO:0070588~calcium ion transmembrane transport,10,2.197802198,0.001481717,"TRPM2, CACNG8, MCOLN3, TRPC5, DENND5B, PKDREJ, PKD2L1, CACNG1, NALCN, MCOLN2",379,119,16792,3.723199042,0.92378287,0.499384539,0.499096709 GOTERM_BP_DIRECT,GO:0048791~calcium ion-regulated exocytosis of neurotransmitter,6,1.318681319,0.001726978,"SYT3, C2CD4C, SYTL5, TC2N, SYT8, SYTL2",379,39,16792,6.816318246,0.950244087,0.499384539,0.499096709 KEGG_PATHWAY,hsa04911:Insulin secretion,8,1.758241758,0.002616353,"RYR2, ADCY9, CCKAR, KCNJ11, FXYD2, KCNN2, FFAR1, PLCB1",153,85,6879,4.23160323,0.414000016,0.264466092,0.263176014 GOTERM_BP_DIRECT,GO:0001878~response to yeast,4,0.879120879,0.002736241,"ANG, PTX3, TAC1, MPO",379,13,16792,13.63263649,0.991405429,0.678196807,0.677805916 GOTERM_MF_DIRECT,GO:0008201~heparin binding,11,2.417582418,0.002985058,"TENM1, CCL23, CXCL11, ADAMTSL5, EPYC, ANOS1, ANG, HRG, MPO, WISP1, PF4",374,160,16881,3.103125,0.792471922,0.363579927,0.36288871 KEGG_PATHWAY,hsa04261:Adrenergic signaling in cardiomyocytes,10,2.197802198,0.003361862,"RYR2, CACNG8, ADCY9, FXYD2, MYL2, CACNG1, ADRA1B, PLCB1, MYH6, MYH7",153,138,6879,3.258027849,0.49690452,0.264466092,0.263176014 GOTERM_CC_DIRECT,GO:0031225~anchored component of membrane,9,1.978021978,0.003965249,"ACHE, SYCE1, VNN1, ITLN1, CNTN2, ENPP6, SMPDL3B, GFRA2, TECTA",410,113,18224,3.540168357,0.685314386,0.150364788,0.148297918 GOTERM_CC_DIRECT,GO:0005605~basal lamina,4,0.879120879,0.004176757,"ACHE, ENTPD2, COL4A5, ANG",410,15,18224,11.85300813,0.704173334,0.150364788,0.148297918 GOTERM_MF_DIRECT,GO:0030246~carbohydrate binding,12,2.637362637,0.004311664,"GALNT14, CD72, CLEC2L, GFPT2, REG1A, ITLN1, CNTN2, KLRD1, CD34, ADGRL2, GALNT9, ADGRL3",374,196,16881,2.763450835,0.896980694,0.363579927,0.36288871 GOTERM_MF_DIRECT,GO:0017147~Wnt-protein binding,5,1.098901099,0.004605199,"FZD1, FZD2, FZD6, FZD9, CTHRC1",374,31,16881,7.280058651,0.911780687,0.363579927,0.36288871 GOTERM_CC_DIRECT,GO:0005581~collagen trimer,8,1.758241758,0.004650457,"COL26A1, COL15A1, SCARA3, LOX, MMP1, COL4A5, CTHRC1, C1QC",410,92,18224,3.865111347,0.742423773,0.150364788,0.148297918 GOTERM_MF_DIRECT,GO:0008093~cytoskeletal adaptor activity,4,0.879120879,0.004838516,"BAIAP2L2, ANK3, GAS2L1, GAS2L2",374,16,16881,11.28409091,0.922014828,0.363579927,0.36288871 GOTERM_BP_DIRECT,GO:2000311~regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity,4,0.879120879,0.005096086,"CACNG8, MAPK8IP2, CNIH3, SHANK1",379,16,16792,11.07651715,0.999859377,1,1 KEGG_PATHWAY,hsa04260:Cardiac muscle contraction,7,1.538461538,0.006058897,"RYR2, CACNG8, FXYD2, MYL2, CACNG1, MYH6, MYH7",153,75,6879,4.196339869,0.710550583,0.264466092,0.263176014 GOTERM_BP_DIRECT,GO:0035567~non-canonical Wnt signaling pathway,4,0.879120879,0.006085945,"FZD1, FZD2, FZD6, FZD9",379,17,16792,10.42495732,0.999975021,1,1 GOTERM_BP_DIRECT,GO:0030193~regulation of blood coagulation,4,0.879120879,0.006085945,"STAB2, HRG, TC2N, FOXA2",379,17,16792,10.42495732,0.999975021,1,1 KEGG_PATHWAY,hsa04020:Calcium signaling pathway,11,2.417582418,0.006121772,"RYR2, CYSLTR1, ADCY9, CCKAR, PPP3R2, CCKBR, CHRM5, BDKRB1, ADRA1B, PLCB1, GRM1",153,179,6879,2.762953226,0.714261907,0.264466092,0.263176014 GOTERM_BP_DIRECT,GO:0006935~chemotaxis,9,1.978021978,0.006371066,"CX3CR1, FOSL1, CCL23, CYSLTR1, CXCL11, PLAU, ANOS1, HRG, CCL26",379,122,16792,3.268480471,0.99998482,1,1 KEGG_PATHWAY,hsa04916:Melanogenesis,8,1.758241758,0.006450392,"FZD1, WNT10A, ADCY9, FZD2, FZD6, TYRP1, FZD9, PLCB1",153,100,6879,3.596862745,0.73290273,0.264466092,0.263176014 GOTERM_MF_DIRECT,GO:0005544~calcium-dependent phospholipid binding,6,1.318681319,0.009011001,"SYT3, C2CD4C, SYTL5, TC2N, SYT8, SYTL2",374,58,16881,4.669278997,0.99144527,0.592473335,0.59134696 GOTERM_BP_DIRECT,GO:0007411~axon guidance,10,2.197802198,0.009995836,"EFNB1, TENM2, SEMA6A, CHL1, BOC, ANOS1, CNTN2, ANK3, NEO1, MATN2",379,159,16792,2.786545195,0.999999973,1,1 GOTERM_BP_DIRECT,GO:0006906~vesicle fusion,6,1.318681319,0.010424662,"SYT3, C2CD4C, SYTL5, TC2N, SYT8, SYTL2",379,59,16792,4.505701892,0.999999987,1,1 GOTERM_BP_DIRECT,GO:0007204~positive regulation of cytosolic calcium ion concentration,9,1.978021978,0.01095236,"CYSLTR1, TRPC5, GJA1, CCKAR, CCKBR, BDKRB1, ADRA1B, HCRT, TAC1",379,134,16792,2.975780727,0.999999995,1,1 GOTERM_MF_DIRECT,GO:0042813~Wnt-activated receptor activity,4,0.879120879,0.01206669,"FZD1, FZD2, FZD6, FZD9",374,22,16881,8.20661157,0.998314485,0.669396163,0.668123546 GOTERM_BP_DIRECT,GO:0006954~inflammatory response,17,3.736263736,0.012158521,"CCL23, ODAM, ACOD1, AOAH, CXCL11, VNN1, CD40LG, BDKRB1, PTX3, PRKD1, TAC1, SMPDL3B, IL17C, TLR3, CCL26, PF4, IL17A",379,379,16792,1.987343447,0.999999999,1,1 GOTERM_MF_DIRECT,GO:0004222~metalloendopeptidase activity,8,1.758241758,0.012726163,"MMP27, ADAMTSL5, MMP16, MMP1, TSHZ2, ADAM23, ADAMTS10, MMP10",374,113,16881,3.195494771,0.998813706,0.669396163,0.668123546 GOTERM_BP_DIRECT,GO:0072089~stem cell proliferation,3,0.659340659,0.012935984,"ABCB1, CD34, NES",379,8,16792,16.61477573,1,1,1 GOTERM_CC_DIRECT,GO:0016324~apical plasma membrane,14,3.076923077,0.014704934,"JAG1, ABCB1, FZD6, AQP6, SHROOM3, RAB27B, GJA1, TMEM235, GJB6, MAL2, CSPG4, LZTS1, CD34, SLC17A3",410,291,18224,2.138429302,0.986578667,0.427913573,0.422031599 GOTERM_BP_DIRECT,GO:0030168~platelet activation,8,1.758241758,0.015264153,"GP9, ENTPD2, CD40LG, FZD6, FGG, TYRO3, HRG, PF4",379,115,16792,3.082161294,1,1,1 GOTERM_BP_DIRECT,GO:0002244~hematopoietic progenitor cell differentiation,6,1.318681319,0.016395065,"SMPD3, PYGO1, ARL11, TMEM190, EML1, HEATR9",379,66,16792,4.027824418,1,1,1 KEGG_PATHWAY,hsa04972:Pancreatic secretion,7,1.538461538,0.016615837,"RYR2, ADCY9, PLA2G12B, CCKAR, FXYD2, RAB27B, PLCB1",153,93,6879,3.384145056,0.967225598,0.567707778,0.564938472 GOTERM_MF_DIRECT,GO:0005261~cation channel activity,4,0.879120879,0.017166381,"TRPM2, PKD2L1, CALHM3, NALCN",374,25,16881,7.221818182,0.999889215,0.808882512,0.807344713 GOTERM_MF_DIRECT,GO:0043621~protein self-association,5,1.098901099,0.018453593,"RYR2, ACHE, TMEM190, CNTN2, AGXT",374,46,16881,4.906126482,0.999944397,0.808882512,0.807344713 GOTERM_BP_DIRECT,GO:0003149~membranous septum morphogenesis,3,0.659340659,0.02018126,"FZD1, FZD2, ID2",379,10,16792,13.29182058,1,1,1 GOTERM_CC_DIRECT,GO:0045211~postsynaptic membrane,11,2.417582418,0.021027786,"GABRB1, CACNG8, TENM2, CHRM5, ANK3, NSG1, HTR3B, CNIH3, LZTS1, SHANK1, GABRG1",410,211,18224,2.317235002,0.997938533,0.556280516,0.548634049 GOTERM_BP_DIRECT,GO:0007166~cell surface receptor signaling pathway,13,2.857142857,0.021870288,"SEMA6A, MPL, PTH2R, ADGRG3, ADGRE1, CYSLTR1, CCKBR, CD19, KLRD1, IL17C, ADGRL2, ADGRL3, IL17A",379,274,16792,2.102112744,1,1,1 GOTERM_BP_DIRECT,GO:0050832~defense response to fungus,4,0.879120879,0.022188139,"GNLY, HRG, MPO, IL17A",379,27,16792,6.563862015,1,1,1 GOTERM_MF_DIRECT,GO:0015278~calcium-release channel activity,3,0.659340659,0.023473099,"RYR2, TRPM2, JPH3",374,11,16881,12.30991736,0.999996251,0.949757698,0.947952075 GOTERM_BP_DIRECT,GO:0035725~sodium ion transmembrane transport,6,1.318681319,0.024290958,"TRPM2, SLC6A8, PKD2L1, NALCN, SLC17A2, SLC17A3",379,73,16792,3.64159468,1,1,1 GOTERM_CC_DIRECT,GO:0030141~secretory granule,6,1.318681319,0.025322215,"RAB3B, ANGPTL6, KLK13, RAB27B, HCRT, MPO",410,74,18224,3.603955175,0.999426451,0.614063705,0.605622967 GOTERM_BP_DIRECT,GO:0007275~multicellular organism development,20,4.395604396,0.027600007,"WNT10A, FZD2, JAG1, DHH, FZD6, TSHZ2, TDRD9, FZD9, SSC5D, ADRA1B, SPRED3, IGSF10, CATSPERG, ID2, SOHLH2, TDRD12, TSSK4, DZIP1, SPATA19, HMX1",379,521,16792,1.700808775,1,1,1 GOTERM_MF_DIRECT,GO:0019905~syntaxin binding,6,1.318681319,0.027751961,"SYT3, C2CD4C, SYTL5, TC2N, SYT8, SYTL2",374,77,16881,3.517119244,0.999999628,1,1 GOTERM_BP_DIRECT,GO:0006816~calcium ion transport,6,1.318681319,0.028311081,"RYR2, TRPM2, CYSLTR1, CACNG8, TRPC5, NALCN",379,76,16792,3.497847521,1,1,1 GOTERM_BP_DIRECT,GO:0050710~negative regulation of cytokine secretion,3,0.659340659,0.028735834,"FFAR4, FOXP3, LGR4",379,12,16792,11.07651715,1,1,1 GOTERM_BP_DIRECT,GO:0007399~nervous system development,13,2.857142857,0.029699365,"TENM1, ACHE, TRPC5, SEMA6A, JAG1, FZD9, PCDHB12, CHRDL1, GFRA2, FGF5, ZEB2, GJB1, MAB21L2",379,287,16792,2.006895093,1,1,1 KEGG_PATHWAY,hsa05217:Basal cell carcinoma,5,1.098901099,0.030856667,"FZD1, WNT10A, FZD2, FZD6, FZD9",153,54,6879,4.163035585,0.998328315,0.840183471,0.836085015 GOTERM_BP_DIRECT,GO:0001764~neuron migration,7,1.538461538,0.031336157,"GJA1, SEMA6A, CCKAR, CHL1, CNTN2, MATN2, ADGRL3",379,105,16792,2.953737907,1,1,1 GOTERM_BP_DIRECT,GO:0007165~signal transduction,37,8.131868132,0.032270431,"TENM1, GABRB1, COL15A1, TENM2, RTKN2, PTPRM, SECTM1, RND2, NTS, WISP1, SHE, ARHGAP42, RPS6KA6, GJA1, CHL1, PLAU, GRB10, CD34, TAS2R4, MPP3, CCL23, CD72, CD300A, FGG, ANK3, LILRB4, CXCL11, ADCY9, TYRO3, LTA, PGR, PRKD1, PLCB1, ASB2, CD244, TLR3, CCL26",379,1161,16792,1.411993573,1,1,1 GOTERM_BP_DIRECT,GO:0032496~response to lipopolysaccharide,9,1.978021978,0.032402232,"CXCL11, UGT1A1, CPS1, GJB6, LTA, BDKRB1, TAC1, MPO, PF4",379,164,16792,2.431430594,1,1,1 KEGG_PATHWAY,hsa04310:Wnt signaling pathway,8,1.758241758,0.032787648,"FZD1, FOSL1, WNT10A, FZD2, PPP3R2, FZD6, FZD9, PLCB1",153,138,6879,2.606422279,0.998887105,0.840183471,0.836085015 GOTERM_BP_DIRECT,GO:0007186~G-protein coupled receptor signaling pathway,30,6.593406593,0.033252592,"CX3CR1, OR2K2, GPR62, ADRA1B, GRM1, ADGRG3, ADGRE1, GPR171, FFAR4, MRGPRX4, FFAR1, TAS2R4, FZD1, CCL23, FZD2, ENTPD2, P2RY14, FZD6, GPR55, FZD9, OR2L2, PTH2R, BAIAP3, CXCL11, CCKBR, LGR4, ADGRL2, PF4, CCL26, ADGRL3",379,899,16792,1.478511744,1,1,1 GOTERM_BP_DIRECT,GO:0034122~negative regulation of toll-like receptor signaling pathway,3,0.659340659,0.033463033,"TYRO3, SMPDL3B, LGR4",379,13,16792,10.22447737,1,1,1 GOTERM_BP_DIRECT,GO:0007512~adult heart development,3,0.659340659,0.033463033,"GJA1, MYH6, MYH7",379,13,16792,10.22447737,1,1,1 GOTERM_CC_DIRECT,GO:0031093~platelet alpha granule lumen,5,1.098901099,0.034762176,"ISLR, FGG, HRG, CLU, PF4",410,55,18224,4.040798226,0.999966225,0.778137936,0.767441882 GOTERM_BP_DIRECT,GO:0050982~detection of mechanical stimulus,3,0.659340659,0.038469406,"DENND5B, PKDREJ, PKD2L1",379,14,16792,9.494157557,1,1,1 GOTERM_BP_DIRECT,GO:0007612~learning,5,1.098901099,0.039241301,"FOSL1, JPH3, SLC12A5, ELAVL4, CNTN2",379,57,16792,3.886497246,1,1,1 GOTERM_MF_DIRECT,GO:0005272~sodium channel activity,3,0.659340659,0.042291487,"TRPM2, PKD2L1, NALCN",374,15,16881,9.027272727,1,1,1 KEGG_PATHWAY,hsa04080:Neuroactive ligand-receptor interaction,12,2.637362637,0.04242445,"GABRB1, CYSLTR1, CCKAR, CCKBR, P2RY14, CHRM5, BDKRB1, PTH2R, ADRA1B, RXFP1, GRM1, GABRG1",153,277,6879,1.947759609,0.999855688,0.966334689,0.961620862 GOTERM_CC_DIRECT,GO:0070382~exocytic vesicle,3,0.659340659,0.043507658,"SYT3, SYTL5, SYTL2",410,15,18224,8.889756098,0.99999761,0.904337741,0.891906982 GOTERM_MF_DIRECT,GO:0004951~cholecystokinin receptor activity,2,0.43956044,0.043704748,"CCKAR, CCKBR",374,2,16881,45.13636364,1,1,1 GOTERM_BP_DIRECT,GO:0038188~cholecystokinin signaling pathway,2,0.43956044,0.044516017,"CCKAR, CCKBR",379,2,16792,44.3060686,1,1,1 GOTERM_BP_DIRECT,GO:0016266~O-glycan processing,5,1.098901099,0.046005694,"GALNT14, MUC2, MUCL1, B3GNT3, GALNT9",379,60,16792,3.692172383,1,1,1 GOTERM_BP_DIRECT,GO:0045669~positive regulation of osteoblast differentiation,5,1.098901099,0.046005694,"GJA1, JAG1, PRKD1, NPNT, CTHRC1",379,60,16792,3.692172383,1,1,1 GOTERM_BP_DIRECT,GO:0043433~negative regulation of sequence-specific DNA binding transcription factor activity,5,1.098901099,0.046005694,"ID2, FZD6, BHLHE40, FOXP3, FOXA2",379,60,16792,3.692172383,1,1,1 GOTERM_CC_DIRECT,GO:0001673~male germ cell nucleus,3,0.659340659,0.049000771,"SYCP1, HSPA2, ACTRT3",410,16,18224,8.334146341,0.999999553,0.950614956,0.937548084 KEGG_PATHWAY,hsa04390:Hippo signaling pathway,8,1.758241758,0.04941569,"FZD1, WNT10A, FZD2, ID2, FZD6, FZD9, CTNNA2, TEAD1",153,151,6879,2.382028308,0.999967634,1,1 GOTERM_CC_DIRECT,GO:0043025~neuronal cell body,13,2.857142857,0.052638459,"TRPC5, SLC12A5, KCNJ11, MPL, STMN2, MAPK8IP2, SEZ6L, TRPM2, S100A5, CNTN2, KCNN2, ANG, TAC1",410,315,18224,1.834394115,0.999999853,0.957361965,0.944202351 GOTERM_BP_DIRECT,GO:0001942~hair follicle development,4,0.879120879,0.053474316,"WNT10A, FZD6, FUZ, LGR4",379,38,16792,4.663796695,1,1,1 GOTERM_BP_DIRECT,GO:0007154~cell communication,4,0.879120879,0.053474316,"FRAS1, GJB1, GJB6, ANG",379,38,16792,4.663796695,1,1,1 GOTERM_BP_DIRECT,GO:0007417~central nervous system development,7,1.538461538,0.054076501,"RPS6KA6, VNN1, NHLH1, ADAM23, CNTN2, NES, HAPLN1",379,120,16792,2.584520668,1,1,1 GOTERM_BP_DIRECT,GO:0030154~cell differentiation,17,3.736263736,0.058988771,"COL15A1, TDRD9, BHLHE41, FOXN4, CHRDL1, RXFP1, IGSF10, ANGPTL6, CATSPERG, NHLH1, ELF5, SOHLH2, TDRD12, TSSK4, SPATA19, ZNF750, KRT6A",379,462,16792,1.630309884,1,1,1 GOTERM_MF_DIRECT,GO:0005520~insulin-like growth factor binding,3,0.659340659,0.059023438,"ESM1, HTRA3, WISP1",374,18,16881,7.522727273,1,1,1 KEGG_PATHWAY,hsa05412:Arrhythmogenic right ventricular cardiomyopathy (ARVC),5,1.098901099,0.060203345,"RYR2, CACNG8, GJA1, CACNG1, CTNNA2",153,67,6879,3.355282411,0.999996846,1,1 GOTERM_CC_DIRECT,GO:0005615~extracellular space,40,8.791208791,0.060689053,"ACHE, COL15A1, DHH, SECTM1, MPO, KLK8, CLU, WISP1, FGF5, IBSP, PLAU, GNLY, EPYC, CTSL, TAC1, CTHRC1, WNT10A, CCL23, ODAM, ABCA3, FGG, OMD, MTUS1, KLK13, SSC5D, MMP10, CXCL11, CD40LG, LOX, LTA, ANOS1, ANG, PTX3, TGFBI, SMPDL3B, IL17C, C1QC, PF4, IL17A, CCL26",410,1347,18224,1.31993409,0.999999988,1,0.989655172 GOTERM_MF_DIRECT,GO:0005201~extracellular matrix structural constituent,5,1.098901099,0.060742248,"COL15A1, ANOS1, COL4A5, HAPLN1, TECTA",374,67,16881,3.368385346,1,1,1 GOTERM_BP_DIRECT,GO:0030539~male genitalia development,3,0.659340659,0.06099657,"WT1, LGR4, TBX3",379,18,16792,7.384344767,1,1,1 GOTERM_BP_DIRECT,GO:0035435~phosphate ion transmembrane transport,3,0.659340659,0.06099657,"SLC37A2, SLC17A2, SLC17A3",379,18,16792,7.384344767,1,1,1 GOTERM_BP_DIRECT,GO:0007200~phospholipase C-activating G-protein coupled receptor signaling pathway,5,1.098901099,0.061352961,"CYSLTR1, CCKAR, CCKBR, ADRA1B, HCRT",379,66,16792,3.356520349,1,1,1 GOTERM_CC_DIRECT,GO:0009986~cell surface,19,4.175824176,0.0643735,"FZD1, ACHE, ABCB1, FZD6, FGG, MPL, FZD9, PKD2L1, ANK3, HSPA2, HTR3B, CLU, CD40LG, MMP16, PLAU, CNTN2, KCNN2, CSPG4, TLR3",410,542,18224,1.558167582,0.999999996,1,0.989655172 GOTERM_BP_DIRECT,GO:0001525~angiogenesis,10,2.197802198,0.065880962,"COL15A1, ESM1, JAG1, ANGPTL6, STAB2, CSPG4, ANG, PRKD1, TGFBI, HRG",379,223,16792,1.98681922,1,1,1 GOTERM_BP_DIRECT,GO:0002282~microglial cell activation involved in immune response,2,0.43956044,0.066027211,"CX3CR1, TLR3",379,3,16792,29.53737907,1,1,1 GOTERM_BP_DIRECT,GO:1904694~negative regulation of vascular smooth muscle contraction,2,0.43956044,0.066027211,"ARHGAP42, DOCK4",379,3,16792,29.53737907,1,1,1 GOTERM_BP_DIRECT,GO:0060923~cardiac muscle cell fate commitment,2,0.43956044,0.066027211,"WT1, TBX3",379,3,16792,29.53737907,1,1,1 GOTERM_BP_DIRECT,GO:0002026~regulation of the force of heart contraction,3,0.659340659,0.067185698,"MYL2, MYH6, MYH7",379,19,16792,6.995695042,1,1,1 GOTERM_BP_DIRECT,GO:0007026~negative regulation of microtubule depolymerization,3,0.659340659,0.067185698,"STMN2, GAS2L1, GAS2L2",379,19,16792,6.995695042,1,1,1 GOTERM_BP_DIRECT,GO:0035338~long-chain fatty-acyl-CoA biosynthetic process,4,0.879120879,0.068212687,"SCD, ELOVL2, THEM5, ACOT12",379,42,16792,4.219625581,1,1,1 GOTERM_BP_DIRECT,GO:0007409~axonogenesis,6,1.318681319,0.070357262,"CCKAR, EPYC, OMD, CNTN2, ANK3, CTNNA2",379,98,16792,2.712616445,1,1,1 GOTERM_BP_DIRECT,GO:0035584~calcium-mediated signaling using intracellular calcium source,3,0.659340659,0.073572218,"RYR2, TRPM2, TENM2",379,20,16792,6.64591029,1,1,1 KEGG_PATHWAY,hsa05205:Proteoglycans in cancer,9,1.978021978,0.074833614,"FZD1, WNT10A, FZD2, PLAU, CTSL, FZD6, GAB1, FZD9, ANK3",153,200,6879,2.023235294,0.999999872,1,1 GOTERM_BP_DIRECT,GO:0070098~chemokine-mediated signaling pathway,5,1.098901099,0.075955986,"CX3CR1, CCL23, CXCL11, CCL26, PF4",379,71,16792,3.120145676,1,1,1 GOTERM_CC_DIRECT,GO:0005922~connexon complex,3,0.659340659,0.079736528,"GJA1, GJB1, GJB6",410,21,18224,6.349825784,1,1,0.989655172 GOTERM_BP_DIRECT,GO:0042730~fibrinolysis,3,0.659340659,0.080144159,"PLAU, FGG, HRG",379,21,16792,6.329438372,1,1,1 GOTERM_BP_DIRECT,GO:0060048~cardiac muscle contraction,4,0.879120879,0.080341389,"RYR2, MYL2, MYH6, MYH7",379,45,16792,3.938317209,1,1,1 GOTERM_BP_DIRECT,GO:0002576~platelet degranulation,6,1.318681319,0.083048405,"ITIH3, ISLR, FGG, HRG, CLU, PF4",379,103,16792,2.580936035,1,1,1 GOTERM_BP_DIRECT,GO:0042493~response to drug,12,2.637362637,0.083430489,"FZD1, FOSL1, NNMT, ABCB1, SLC12A5, UGT1A1, KCNJ11, CPS1, LOX, ABCA3, LTA, PTPRM",379,304,16792,1.748923761,1,1,1 GOTERM_MF_DIRECT,GO:0005253~anion channel activity,2,0.43956044,0.085504289,"GABRB1, AQP6",374,4,16881,22.56818182,1,1,1 GOTERM_BP_DIRECT,GO:0007140~male meiosis,3,0.659340659,0.08688999,"TDRD9, TDRD12, HSPA2",379,22,16792,6.041736627,1,1,1 GOTERM_BP_DIRECT,GO:0061073~ciliary body morphogenesis,2,0.43956044,0.087055367,"FOXE3, JAG1",379,4,16792,22.1530343,1,1,1 GOTERM_BP_DIRECT,GO:0048023~positive regulation of melanin biosynthetic process,2,0.43956044,0.087055367,"ZEB2, TYRP1",379,4,16792,22.1530343,1,1,1 GOTERM_BP_DIRECT,GO:0072086~specification of loop of Henle identity,2,0.43956044,0.087055367,"IRX1, IRX3",379,4,16792,22.1530343,1,1,1 GOTERM_BP_DIRECT,GO:0019695~choline metabolic process,2,0.43956044,0.087055367,"DMGDH, ENPP6",379,4,16792,22.1530343,1,1,1 GOTERM_BP_DIRECT,GO:1901896~positive regulation of calcium-transporting ATPase activity,2,0.43956044,0.087055367,"RYR2, HSPA2",379,4,16792,22.1530343,1,1,1 GOTERM_CC_DIRECT,GO:0043005~neuron projection,10,2.197802198,0.087176775,"CX3CR1, FOSL1, TENM1, TRPM2, TENM2, MPL, STMN2, BDKRB1, ANK3, SHANK1",410,237,18224,1.87547597,1,1,0.989655172 KEGG_PATHWAY,hsa04550:Signaling pathways regulating pluripotency of stem cells,7,1.538461538,0.089237917,"FZD1, WNT10A, FZD2, ID2, FZD6, FZD9, TBX3",153,140,6879,2.248039216,0.999999995,1,1 GOTERM_MF_DIRECT,GO:0008092~cytoskeletal protein binding,4,0.879120879,0.089450128,"FRMD5, PKD2L1, ANK3, PTPN3",374,48,16881,3.761363636,1,1,1 GOTERM_MF_DIRECT,GO:0008009~chemokine activity,4,0.879120879,0.093799228,"CCL23, CXCL11, CCL26, PF4",374,49,16881,3.684601113,1,1,1 GOTERM_BP_DIRECT,GO:0006936~muscle contraction,6,1.318681319,0.094014139,"TRIM72, GJA1, SLC6A8, CACNG1, MYH6, MYH7",379,107,16792,2.484452445,1,1,1 GOTERM_BP_DIRECT,GO:0006810~transport,13,2.857142857,0.095995193,"GABRB1, ABCB1, SLC12A5, ABCA3, SLC35F4, AQP6, GJA1, TSPO2, SLC6A8, GJB1, FXYD2, CACNG1, SLC25A47",379,348,16792,1.655111758,1,1,1