"","ONTOLOGY","ID","Description","GeneRatio","BgRatio","pvalue","p.adjust","qvalue","geneID","Count"
"GO:0062197","BP","GO:0062197","cellular response to chemical stress","51/173","396/21081",1.1196057917918e-46,4.75720500932334e-43,1.85265295231232e-43,"G6PD/FABP1/MAPK3/ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MAPK8/MDM2/PPARG/PTGS2/IL6/SRC/CDK2/NQO1/MAPK1/NOS3/CCNA2/CHUK/AKT1/PARP1/TLR4/LRRK2/EGFR/AKR1B1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/GSR/SNCA/MMP3/MMP9/MPO/MAPK10/SIRT1/ABL1/MMP2/NOX4/CYP1B1/CDK1/MAPT/MAPT/MAPT",51
"GO:0034599","BP","GO:0034599","cellular response to oxidative stress","47/173","344/21081",4.00532975213215e-44,8.50932305840475e-41,3.3138833528167e-41,"G6PD/FABP1/MAPK3/ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MAPK8/MDM2/IL6/SRC/CDK2/NQO1/MAPK1/NOS3/CCNA2/CHUK/AKT1/PARP1/TLR4/LRRK2/EGFR/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/GSR/SNCA/MMP3/MMP9/MPO/SIRT1/ABL1/MMP2/NOX4/CYP1B1/CDK1/MAPT/MAPT/MAPT",47
"GO:0062012","BP","GO:0062012","regulation of small molecule metabolic process","47/173","494/21081",1.11962774266219e-36,1.58576609285721e-33,6.17563091742092e-34,"NR1H4/FABP5/PPARA/HMGCR/FABP1/NOS2/CES1/CES1/RORA/NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SREBF2/CNR1/PPARG/PTGS2/NR1H2/SRC/GSK3B/HTR2A/MTOR/NQO1/NOS3/AKT1/PARP1/NOS1/HDAC4/INSR/SNCA/PPP1CA/SIRT1/STAT3/APP/PFKFB3/FASN/ACACA/ACACA/OGT/VCP/EP300/PSEN1",47
"GO:0034614","BP","GO:0034614","cellular response to reactive oxygen species","34/173","183/21081",1.57791601142709e-36,1.67614128313842e-33,6.52758939464048e-34,"FABP1/MAPK3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MAPK8/MDM2/IL6/SRC/CDK2/NQO1/MAPK1/NOS3/CCNA2/CHUK/AKT1/LRRK2/EGFR/MMP3/MMP9/MPO/SIRT1/ABL1/MMP2/CYP1B1/CDK1/MAPT/MAPT/MAPT",34
"GO:0072593","BP","GO:0072593","reactive oxygen species metabolic process","39/173","321/21081",1.91825238751354e-34,1.630130878909e-31,6.34840579615006e-32,"G6PD/NOS2/ALOX5/ALOX5/RORA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTGS2/AGTR1/MTOR/NQO1/NOS3/AKT1/TLR4/NOS1/LRRK2/EGFR/HDAC4/XDH/INSR/SNCA/F2/MMP3/RHOA/MPO/MAOB/STAT3/MAPK14/NOX4/CYP1B1/MAPT/MAPT/MAPT",39
"GO:0062013","BP","GO:0062013","positive regulation of small molecule metabolic process","31/173","161/21081",7.74715215055191e-34,5.48627491461584e-31,2.13658301415221e-31,"NR1H4/PPARA/FABP1/NOS2/CES1/CES1/NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/PTGS2/NR1H2/SRC/HTR2A/NOS3/AKT1/NOS1/INSR/SNCA/SIRT1/STAT3/APP/PFKFB3/VCP/PSEN1",31
"GO:0032496","BP","GO:0032496","response to lipopolysaccharide","40/173","396/21081",4.0037185534802e-32,2.43025716196248e-29,9.46442942266297e-30,"NR1H4/MAPK3/NOS2/IDO1/SERPINE1/NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MAPK8/CNR1/PTGS2/IL6/SRC/PRKCA/CDK4/MAPK1/NOS3/CHUK/AKT1/TLR4/NOS1/MIF/MIF/SNCA/RHOA/CXCL8/MPO/CTSG/MAOB/ABL1/MAPK14/C5AR1/ELANE/ELANE",40
"GO:0000302","BP","GO:0000302","response to reactive oxygen species","34/173","251/21081",1.19158595865073e-31,6.32881092288367e-29,2.46470148289334e-29,"FABP1/MAPK3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MAPK8/MDM2/IL6/SRC/CDK2/NQO1/MAPK1/NOS3/CCNA2/CHUK/AKT1/LRRK2/EGFR/MMP3/MMP9/MPO/SIRT1/ABL1/MMP2/CYP1B1/CDK1/MAPT/MAPT/MAPT",34
"GO:0002237","BP","GO:0002237","response to molecule of bacterial origin","40/173","424/21081",5.93300167777087e-31,2.80103601431649e-28,1.09083960671998e-28,"NR1H4/MAPK3/NOS2/IDO1/SERPINE1/NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MAPK8/CNR1/PTGS2/IL6/SRC/PRKCA/CDK4/MAPK1/NOS3/CHUK/AKT1/TLR4/NOS1/MIF/MIF/SNCA/RHOA/CXCL8/MPO/CTSG/MAOB/ABL1/MAPK14/C5AR1/ELANE/ELANE",40
"GO:1903409","BP","GO:1903409","reactive oxygen species biosynthetic process","28/173","150/21081",3.34497143577149e-30,1.42127836305931e-27,5.53504747056083e-28,"NOS2/ALOX5/ALOX5/RORA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTGS2/MTOR/NQO1/NOS3/AKT1/TLR4/NOS1/HDAC4/INSR/SNCA/RHOA/MPO/MAOB/STAT3/NOX4/CYP1B1",28
"GO:0018209","BP","GO:0018209","peptidyl-serine modification","36/173","350/21081",3.58360805255678e-29,1.38425005593761e-26,5.39084388384618e-27,"MAPK3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MAPK8/PTGS2/IL6/PRKCB/SRC/GSK3B/PRKCA/CDK2/CSNK2A1/CSNK2A2/IKBKB/CHEK2/MTOR/PIK3CA/MAPK1/CHUK/AKT1/PARP1/NOS1/LRRK2/EGFR/MIF/MIF/SNCA/MAPK14/CDK1/APP",36
"GO:2000377","BP","GO:2000377","regulation of reactive oxygen species metabolic process","31/173","227/21081",5.43022731859794e-29,1.89337316373977e-26,7.37358044220663e-27,"G6PD/ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTGS2/AGTR1/MTOR/AKT1/TLR4/EGFR/HDAC4/XDH/INSR/SNCA/F2/MMP3/RHOA/STAT3/MAPK14/NOX4/CYP1B1/MAPT/MAPT/MAPT",31
"GO:0018105","BP","GO:0018105","peptidyl-serine phosphorylation","35/173","327/21081",5.79285740847658e-29,1.89337316373977e-26,7.37358044220663e-27,"MAPK3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MAPK8/PTGS2/IL6/PRKCB/SRC/GSK3B/PRKCA/CDK2/CSNK2A1/CSNK2A2/IKBKB/CHEK2/MTOR/PIK3CA/MAPK1/CHUK/AKT1/NOS1/LRRK2/EGFR/MIF/MIF/SNCA/MAPK14/CDK1/APP",35
"GO:0010876","BP","GO:0010876","lipid localization","40/173","484/21081",1.03180746538689e-28,3.13153565744922e-26,1.2195498763821e-26,"NPC1L1/CYP19A1/NR1H4/FABP4/FABP5/PPARA/FABP1/PTPN11/NOS2/CES1/CES1/NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SREBF2/DRD2/PPARG/IL6/AGTR1/NR1H2/DRD3/AKT1/MIF/MIF/AKR1C1/ACE/SIRT1/STAT5B/ABCC1/ABCC1/CFTR/ACACA/ACACA/CETP",40
"GO:0071902","BP","GO:0071902","positive regulation of protein serine/threonine kinase activity","36/173","383/21081",8.76514114563293e-28,2.48287231518629e-25,9.6693346532877e-26,"MAPK3/PTPN11/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SRC/ERBB2/HTR2A/CSK/PIK3CG/MAPK1/AKT1/TLR4/LRRK2/EGFR/CCND1/INSR/MIF/MIF/SNCA/RHOA/MAPK10/SIRT1/MAPK14/NOX4/CDK1/PPP2CA/C5AR1/ELANE/ELANE/PSEN1",36
"GO:0010001","BP","GO:0010001","glial cell differentiation","31/173","253/21081",1.66007188123655e-27,4.4085283896088e-25,1.71686381401569e-25,"MAPK3/PTPN11/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/IL6/DRD3/ERBB2/CSK/MTOR/MAPK1/AKT1/TLR4/EGFR/F2/RHOA/ABL1/STAT3/CDK1/APP/MAPT/MAPT/MAPT/C5AR1/PSEN1",31
"GO:0048708","BP","GO:0048708","astrocyte differentiation","23/173","101/21081",4.38186205135704e-27,1.095207756248e-24,4.26519327847261e-25,"MAPK3/PTPN11/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/MAPK1/TLR4/EGFR/F2/ABL1/STAT3/APP/MAPT/MAPT/MAPT/C5AR1/PSEN1",23
"GO:0019216","BP","GO:0019216","regulation of lipid metabolic process","37/173","452/21081",2.13596335918481e-26,5.04206017398681e-24,1.96358736879446e-24,"NR1H4/FABP5/PPARA/HMGCR/FABP1/CES1/CES1/RORA/NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SREBF2/CNR1/PPARG/PTGS2/AGTR1/NR1H2/DRD3/SRC/HTR2A/MTOR/PIK3CG/CDK4/AKT1/PTK2/F2/SIRT1/STAT5B/FASN/ACACA/ACACA",37
"GO:0009636","BP","GO:0009636","response to toxic substance","31/173","277/21081",2.79430734283177e-26,6.24895363141695e-24,2.43360174123631e-24,"AKR1B10/SRD5A1/FABP1/MAPK3/PTGS1/CES1/CES1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/MDM2/PTGS2/CDK4/NQO1/MAPK1/NOS3/PIM1/CHUK/GSR/MPO/MAOB/EPHX1/CYP1B1/ABCG2/CDK1",31
"GO:2000379","BP","GO:2000379","positive regulation of reactive oxygen species metabolic process","24/173","127/21081",4.01688511180714e-26,8.53387242003426e-24,3.32344389250569e-24,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTGS2/AGTR1/MTOR/AKT1/TLR4/EGFR/HDAC4/XDH/INSR/SNCA/F2/MAPK14/NOX4/MAPT/MAPT/MAPT",24
"GO:2001234","BP","GO:2001234","negative regulation of apoptotic signaling pathway","30/173","263/21081",1.0749787828104e-25,2.17504040388637e-23,8.47050950665636e-24,"SERPINE1/BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/MDM2/PTGS2/SRC/GSK3B/CSNK2A1/CSNK2A2/NOS3/AKT1/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/MIF/MIF/MMP9/SIRT1/PSEN1",30
"GO:0045862","BP","GO:0045862","positive regulation of proteolysis","35/173","423/21081",3.95013698336337e-25,7.62915092832316e-23,2.97110781715178e-23,"CTSD/MAPK3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MDM2/PPARG/SRC/GSK3B/AKT1/LRRK2/XDH/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/PTK2/SNCA/RHOA/SIRT1/STAT3/MAPK14/APP/MAPT/MAPT/MAPT/OGT/VCP/PSEN1",35
"GO:0008202","BP","GO:0008202","steroid metabolic process","33/173","369/21081",8.74628558221626e-25,1.61578119299291e-22,6.29252216715971e-23,"NPC1L1/CYP19A1/G6PD/NR1H4/HMGCR/SRD5A1/NR1I2/ESR1/CES1/CES1/RORA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SREBF2/AGTR1/CYP26A1/AKR1B1/AKR1C1/SIRT1/STAT5B/CYP1B1/APP/CFTR/FASN/ACACA/ACACA/CETP",33
"GO:0071222","BP","GO:0071222","cellular response to lipopolysaccharide","29/173","257/21081",1.01704909175408e-24,1.80060066285962e-22,7.01228584314654e-23,"NR1H4/MAPK3/NOS2/SERPINE1/NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MAPK8/IL6/SRC/PRKCA/CDK4/MAPK1/NOS3/AKT1/TLR4/MIF/MIF/RHOA/CXCL8/CTSG/ABL1/MAPK14",29
"GO:0042063","BP","GO:0042063","gliogenesis","32/173","351/21081",2.64744763471057e-24,4.49960199995409e-22,1.75233165548001e-22,"MAPK3/PTPN11/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/PPARG/IL6/DRD3/ERBB2/CSK/MTOR/MAPK1/AKT1/TLR4/EGFR/F2/RHOA/ABL1/STAT3/CDK1/APP/MAPT/MAPT/MAPT/C5AR1/PSEN1",32
"GO:0071216","BP","GO:0071216","cellular response to biotic stimulus","30/173","296/21081",3.64971796129405e-24,5.81860267403446e-22,2.26600522812356e-22,"NR1H4/MAPK3/NOS2/SERPINE1/NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MAPK8/IL6/SRC/GSK3B/PRKCA/CDK4/MAPK1/NOS3/AKT1/TLR4/MIF/MIF/RHOA/CXCL8/CTSG/ABL1/MAPK14",30
"GO:0043405","BP","GO:0043405","regulation of MAP kinase activity","33/173","386/21081",3.69739402680467e-24,5.81860267403446e-22,2.26600522812356e-22,"HMGCR/MAPK3/PTPN11/IGF1R/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SRC/ERBB2/HTR2A/CSK/PIK3CG/MAPK1/TLR4/LRRK2/EGFR/INSR/MIF/MIF/MAPK10/MAPK14/NOX4/CDK1/PPP2CA/C5AR1/ELANE/ELANE/PSEN1",33
"GO:0010888","BP","GO:0010888","negative regulation of lipid storage","15/173","30/21081",3.87165551484602e-24,5.87523724377883e-22,2.28806107869847e-22,"PPARA/CES1/CES1/NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/IL6/NR1H2",15
"GO:0033002","BP","GO:0033002","muscle cell proliferation","29/173","270/21081",4.23317331947489e-24,6.2023287704996e-22,2.41544408646626e-22,"HMGCR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/MDM2/PPARG/PTGS2/IL6/MTOR/MAPK1/NOS3/PIM1/AKT1/EGFR/HDAC4/AKR1B1/MMP9/MMP2/STAT3/MAPK14/CDK1/ELANE/ELANE",29
"GO:0071219","BP","GO:0071219","cellular response to molecule of bacterial origin","29/173","272/21081",5.23560149702067e-24,7.41535692028027e-22,2.88784756256719e-22,"NR1H4/MAPK3/NOS2/SERPINE1/NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MAPK8/IL6/SRC/PRKCA/CDK4/MAPK1/NOS3/AKT1/TLR4/MIF/MIF/RHOA/CXCL8/CTSG/ABL1/MAPK14",29
"GO:0043406","BP","GO:0043406","positive regulation of MAP kinase activity","30/173","302/21081",6.6058732073583e-24,9.05430814776303e-22,3.52612315177156e-22,"MAPK3/PTPN11/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SRC/ERBB2/HTR2A/CSK/PIK3CG/MAPK1/TLR4/LRRK2/EGFR/INSR/MIF/MIF/MAPK10/MAPK14/NOX4/CDK1/C5AR1/ELANE/ELANE/PSEN1",30
"GO:0032757","BP","GO:0032757","positive regulation of interleukin-8 production","19/173","72/21081",6.87761024892165e-24,9.13217685864628e-22,3.55644845766607e-22,"SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/TLR4/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/STAT3/ELANE/ELANE",19
"GO:0150076","BP","GO:0150076","neuroinflammatory response","21/173","102/21081",8.32003723032855e-24,1.07126782398988e-21,4.171961252337e-22,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTGS2/IL6/LRRK2/EGFR/SNCA/MMP3/MMP9/APP/MAPT/MAPT/MAPT/C5AR1/PSEN1",21
"GO:0070997","BP","GO:0070997","neuron death","34/173","440/21081",1.89757874678844e-23,2.37141532208944e-21,9.23527489149051e-22,"G6PD/PPARA/BACE1/BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/XIAP/GSK3B/MTOR/PIK3CA/NQO1/AKT1/PARP1/TLR4/LRRK2/HDAC4/SNCA/RHOA/SIRT1/ABL1/STAT3/APP/MAPT/MAPT/MAPT/C5AR1/PSEN1",34
"GO:0045834","BP","GO:0045834","positive regulation of lipid metabolic process","24/173","163/21081",2.15125926070938e-23,2.61162874250119e-21,1.01707655874741e-21,"NR1H4/PPARA/FABP1/CES1/CES1/NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/PTGS2/AGTR1/NR1H2/SRC/HTR2A/MTOR/AKT1/PTK2/F2",24
"GO:0048661","BP","GO:0048661","positive regulation of smooth muscle cell proliferation","22/173","127/21081",3.89468695016442e-23,4.59681245868017e-21,1.79018944025101e-21,"HMGCR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/MDM2/PTGS2/IL6/MTOR/AKT1/EGFR/HDAC4/AKR1B1/MMP9/MMP2/ELANE/ELANE",22
"GO:0048143","BP","GO:0048143","astrocyte activation","16/173","43/21081",4.56312889382805e-23,5.24019855942577e-21,2.04075067456549e-21,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/EGFR/APP/MAPT/MAPT/MAPT/C5AR1/PSEN1",16
"GO:0050729","BP","GO:0050729","positive regulation of inflammatory response","25/173","194/21081",7.44775079134663e-23,8.3277613453768e-21,3.24317569085787e-21,"FABP4/IDO1/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CNR1/PTGS2/IL6/AGTR1/PIK3CG/TLR4/LRRK2/EGFR/SNCA/STAT5B/STAT3/ABCC1/ABCC1/IL2",25
"GO:1901216","BP","GO:1901216","positive regulation of neuron death","21/173","113/21081",8.338177242061e-23,9.08433720551723e-21,3.53781771242103e-21,"BACE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GSK3B/MTOR/NQO1/PARP1/TLR4/HDAC4/SNCA/RHOA/ABL1/MAPT/MAPT/MAPT",21
"GO:1901214","BP","GO:1901214","regulation of neuron death","32/173","402/21081",1.75553023442839e-22,1.86481199152155e-20,7.26235139084585e-21,"G6PD/PPARA/BACE1/BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/GSK3B/MTOR/PIK3CA/NQO1/AKT1/PARP1/TLR4/LRRK2/HDAC4/SNCA/RHOA/SIRT1/ABL1/STAT3/MAPT/MAPT/MAPT/C5AR1/PSEN1",32
"GO:0018108","BP","GO:0018108","peptidyl-tyrosine phosphorylation","32/173","410/21081",3.20852656232426e-22,3.32512911300385e-20,1.29494319793934e-20,"MAPK3/PTPN11/IGF1R/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/SRC/ERBB2/HTR2A/CSK/MTOR/WEE1/EGFR/INSR/PTK2/MIF/MIF/ACE/ABL1/STAT3/TYK2/NOX4/APP/IL2/PPP2CA/PSEN1",32
"GO:0018212","BP","GO:0018212","peptidyl-tyrosine modification","32/173","413/21081",4.00891356366737e-22,4.05568422191016e-20,1.57945165967045e-20,"MAPK3/PTPN11/IGF1R/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/SRC/ERBB2/HTR2A/CSK/MTOR/WEE1/EGFR/INSR/PTK2/MIF/MIF/ACE/ABL1/STAT3/TYK2/NOX4/APP/IL2/PPP2CA/PSEN1",32
"GO:1905953","BP","GO:1905953","negative regulation of lipid localization","18/173","75/21081",7.36929195585729e-22,7.28188872568317e-20,2.83586951153187e-20,"PPARA/PTPN11/CES1/CES1/NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SREBF2/PPARG/IL6/NR1H2/AKT1",18
"GO:1905952","BP","GO:1905952","regulation of lipid localization","24/173","189/21081",8.11233381344914e-22,7.72540089231399e-20,3.00859154543301e-20,"CYP19A1/PPARA/PTPN11/CES1/CES1/NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SREBF2/PPARG/IL6/AGTR1/NR1H2/AKT1/MIF/MIF/SIRT1/CETP",24
"GO:0010883","BP","GO:0010883","regulation of lipid storage","17/173","62/21081",8.36357827833476e-22,7.72540089231399e-20,3.00859154543301e-20,"PPARA/CES1/CES1/NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SREBF2/PPARG/IL6/NR1H2/SIRT1",17
"GO:0014002","BP","GO:0014002","astrocyte development","17/173","62/21081",8.36357827833476e-22,7.72540089231399e-20,3.00859154543301e-20,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/TLR4/EGFR/APP/MAPT/MAPT/MAPT/C5AR1/PSEN1",17
"GO:0043281","BP","GO:0043281","regulation of cysteine-type endopeptidase activity involved in apoptotic process","26/173","240/21081",9.03435940317746e-22,8.05050692197233e-20,3.13520131828926e-20,"FABP1/CTSD/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MDM2/XIAP/PPARG/PTGS2/SRC/CSNK2A1/AKT1/XDH/SNCA/MMP9/RHOA/SIRT1/MAPT/MAPT/MAPT/VCP",26
"GO:0038034","BP","GO:0038034","signal transduction in absence of ligand","19/173","91/21081",9.28394537953976e-22,8.05050692197233e-20,3.13520131828926e-20,"BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/GSK3B/AKT1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/PPP1CA/IL2",19
"GO:0097192","BP","GO:0097192","extrinsic apoptotic signaling pathway in absence of ligand","19/173","91/21081",9.28394537953976e-22,8.05050692197233e-20,3.13520131828926e-20,"BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/GSK3B/AKT1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/PPP1CA/IL2",19
"GO:2001233","BP","GO:2001233","regulation of apoptotic signaling pathway","33/173","462/21081",1.07051754213504e-21,9.09725807306355e-20,3.54284963418164e-20,"SERPINE1/BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/MAPK8/MDM2/PTGS2/SRC/GSK3B/CSNK2A1/CSNK2A2/NOS3/AKT1/PARP1/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/MIF/MIF/PPP1CA/MMP9/SIRT1/PSEN1",33
"GO:2001239","BP","GO:2001239","regulation of extrinsic apoptotic signaling pathway in absence of ligand","17/173","63/21081",1.137426482064e-21,9.3551271427086e-20,3.64327454592113e-20,"BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/AKT1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/PPP1CA",17
"GO:1901099","BP","GO:1901099","negative regulation of signal transduction in absence of ligand","16/173","51/21081",1.16691395284433e-21,9.3551271427086e-20,3.64327454592113e-20,"BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/AKT1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",16
"GO:2001240","BP","GO:2001240","negative regulation of extrinsic apoptotic signaling pathway in absence of ligand","16/173","51/21081",1.16691395284433e-21,9.3551271427086e-20,3.64327454592113e-20,"BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/AKT1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",16
"GO:0051222","BP","GO:0051222","positive regulation of protein transport","31/173","394/21081",1.21248622229498e-21,9.54047029357659e-20,3.71545485662321e-20,"NR1H4/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SREBF2/MAPK8/DRD2/MDM2/PTGS2/IL6/NR1H2/SRC/GSK3B/ERBB2/CSNK2A2/MAPK1/TLR4/EGFR/MIF/MIF/MAPK14/CDK1/CD38/CFTR/IL2/PSEN1",31
"GO:0050708","BP","GO:0050708","regulation of protein secretion","31/173","397/21081",1.51781354121702e-21,1.15789258088657e-19,4.50931398633409e-20,"NR1H4/HMGCR/PTPN11/NOS2/ALOX5/ALOX5/NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/CNR1/IL6/NR1H2/DRD3/SRC/PRKCA/TLR4/EGFR/MIF/MIF/GLP1R/CD38/CFTR/DPP4/IL2",31
"GO:1904996","BP","GO:1904996","positive regulation of leukocyte adhesion to vascular endothelial cell","14/173","32/21081",1.52605282489169e-21,1.15789258088657e-19,4.50931398633409e-20,"ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/RHOA/ELANE/ELANE",14
"GO:0042116","BP","GO:0042116","macrophage activation","21/173","130/21081",1.85041734689542e-21,1.37937250999274e-19,5.37184869680443e-20,"RORA/NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/TLR4/LRRK2/MIF/MIF/SNCA/APP/MAPT/MAPT/MAPT/C5AR1",21
"GO:0046890","BP","GO:0046890","regulation of lipid biosynthetic process","25/173","221/21081",1.97665201536551e-21,1.44806800229104e-19,5.63937743766712e-20,"NR1H4/FABP5/HMGCR/CES1/CES1/NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SREBF2/PTGS2/NR1H2/HTR2A/MTOR/CDK4/AKT1/SIRT1/FASN/ACACA/ACACA",25
"GO:1901617","BP","GO:1901617","organic hydroxy compound biosynthetic process","27/173","277/21081",2.33814246438044e-21,1.68385886968686e-19,6.55764487779848e-20,"NPC1L1/CYP19A1/G6PD/NR1H4/HMGCR/SLC6A3/SLC6A3/CES1/CES1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SREBF2/AKR1B1/SNCA/MC1R/SIRT1/TYR/CFTR/FASN/ACACA/ACACA",27
"GO:0048660","BP","GO:0048660","regulation of smooth muscle cell proliferation","24/173","198/21081",2.50396756523034e-21,1.77322636411062e-19,6.9056789693721e-20,"HMGCR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/MDM2/PPARG/PTGS2/IL6/MTOR/NOS3/AKT1/EGFR/HDAC4/AKR1B1/MMP9/MMP2/ELANE/ELANE",24
"GO:0006809","BP","GO:0006809","nitric oxide biosynthetic process","19/173","96/21081",2.77357059725999e-21,1.93195106028815e-19,7.5238187728951e-20,"NOS2/RORA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTGS2/MTOR/NQO1/NOS3/AKT1/TLR4/NOS1/INSR/CYP1B1",19
"GO:0048659","BP","GO:0048659","smooth muscle cell proliferation","24/173","200/21081",3.19157490537354e-21,2.18725835047293e-19,8.51809125848423e-20,"HMGCR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/MDM2/PPARG/PTGS2/IL6/MTOR/NOS3/AKT1/EGFR/HDAC4/AKR1B1/MMP9/MMP2/ELANE/ELANE",24
"GO:0002685","BP","GO:0002685","regulation of leukocyte migration","26/173","254/21081",3.88664338204665e-21,2.62132503655813e-19,1.02085269784082e-19,"CYP19A1/MAPK3/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CXCR3/IL6/MAPK1/AKT1/PTK2/MIF/MIF/RHOA/CXCL8/MAPK14/APP/DPP4/C5AR1/ELANE/ELANE",26
"GO:1904951","BP","GO:1904951","positive regulation of establishment of protein localization","31/173","411/21081",4.22286774090087e-21,2.80358828610747e-19,1.09183356721977e-19,"NR1H4/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SREBF2/MAPK8/DRD2/MDM2/PTGS2/IL6/NR1H2/SRC/GSK3B/ERBB2/CSNK2A2/MAPK1/TLR4/EGFR/MIF/MIF/MAPK14/CDK1/CD38/CFTR/IL2/PSEN1",31
"GO:0046209","BP","GO:0046209","nitric oxide metabolic process","19/173","101/21081",7.77524990980158e-21,5.0826210564226e-19,1.97938345881912e-19,"NOS2/RORA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTGS2/MTOR/NQO1/NOS3/AKT1/TLR4/NOS1/INSR/CYP1B1",19
"GO:0010038","BP","GO:0010038","response to metal ion","30/173","386/21081",8.28637995254662e-21,5.3346709724804e-19,2.07754215078202e-19,"G6PD/FABP4/MAPK3/SLC6A3/SLC6A3/BACE1/TERT/MAPK8/DRD2/MDM2/PTGS2/CDK4/NQO1/MAPK1/CHUK/AKT1/PARP1/LRRK2/EGFR/CCND1/SNCA/PPP1CA/MMP9/MAOB/CDK1/APP/MAPT/MAPT/MAPT/PPP2CA",30
"GO:0061900","BP","GO:0061900","glial cell activation","18/173","85/21081",8.66924297284605e-21,5.49785274501834e-19,2.14109190154187e-19,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/LRRK2/EGFR/SNCA/APP/MAPT/MAPT/MAPT/C5AR1/PSEN1",18
"GO:0097193","BP","GO:0097193","intrinsic apoptotic signaling pathway","28/173","322/21081",9.00940360352795e-21,5.62955233991033e-19,2.19238118649318e-19,"BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MDM2/PTGS2/SRC/CHEK2/AKT1/PARP1/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/MIF/MIF/MMP9/SIRT1/ABL1/CYP1B1/EP300",28
"GO:0061044","BP","GO:0061044","negative regulation of vascular wound healing","11/173","15/21081",1.09327994537628e-20,6.73238621435336e-19,2.62187044108545e-19,"ALOX5/ALOX5/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",11
"GO:0002791","BP","GO:0002791","regulation of peptide secretion","31/173","427/21081",1.2967968621877e-20,7.87155695347932e-19,3.06551077798355e-19,"NR1H4/HMGCR/PTPN11/NOS2/ALOX5/ALOX5/NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/CNR1/IL6/NR1H2/DRD3/SRC/PRKCA/TLR4/EGFR/MIF/MIF/GLP1R/CD38/CFTR/DPP4/IL2",31
"GO:2001057","BP","GO:2001057","reactive nitrogen species metabolic process","19/173","104/21081",1.40380439379071e-20,8.40107728058693e-19,3.271727957063e-19,"NOS2/RORA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTGS2/MTOR/NQO1/NOS3/AKT1/TLR4/NOS1/INSR/CYP1B1",19
"GO:0032637","BP","GO:0032637","interleukin-8 production","20/173","123/21081",1.52253763513896e-20,8.86200330370609e-19,3.45123166898118e-19,"NOS2/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/TLR4/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/STAT3/ELANE/ELANE",20
"GO:2001237","BP","GO:2001237","negative regulation of extrinsic apoptotic signaling pathway","20/173","123/21081",1.52253763513896e-20,8.86200330370609e-19,3.45123166898118e-19,"SERPINE1/BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/SRC/GSK3B/NOS3/AKT1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",20
"GO:0048015","BP","GO:0048015","phosphatidylinositol-mediated signaling","24/173","215/21081",1.81299108849396e-20,1.04099988310957e-18,4.05408533586416e-19,"MAPK3/IGF1R/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SRC/ERBB2/HTR2A/PIK3CA/PIK3CG/MAPK1/AKT1/EGFR/INSR/PTK2/F2/RHOA/SIRT1/OGT",24
"GO:1901653","BP","GO:1901653","cellular response to peptide","31/173","434/21081",2.08713356275427e-20,1.18243073441905e-18,4.60487573424521e-19,"NR1H4/SRD5A1/PTPN11/BACE1/IGF1R/MDM2/PPARG/AGTR1/PRKCB/SRC/GSK3B/CSK/PIK3CA/CDK4/CCNA2/AKT1/PARP1/TLR4/AKR1B1/INSR/PTK2/SIRT1/STAT5B/GLP1R/STAT3/ABCC1/ABCC1/ESRRA/APP/OGT/PSEN1",31
"GO:0031334","BP","GO:0031334","positive regulation of protein-containing complex assembly","27/173","302/21081",2.27561598413808e-20,1.27224898902667e-18,4.9546652729433e-19,"ESR1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NR1H2/SRC/GSK3B/MTOR/PARP1/TLR4/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SNCA/MMP3/RHOA/MAPT/MAPT/MAPT/VCP",27
"GO:0051896","BP","GO:0051896","regulation of protein kinase B signaling","26/173","273/21081",2.45106147435936e-20,1.33520002622473e-18,5.19982272293241e-19,"PTPN11/ESR1/IGF1R/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/DRD3/SRC/ERBB2/MTOR/PIK3CA/PIK3CG/AKT1/EGFR/XDH/INSR/PTK2/MC1R/SIRT1/NOX4",26
"GO:2000116","BP","GO:2000116","regulation of cysteine-type endopeptidase activity","26/173","273/21081",2.45106147435936e-20,1.33520002622473e-18,5.19982272293241e-19,"FABP1/CTSD/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MDM2/XIAP/PPARG/PTGS2/SRC/CSNK2A1/AKT1/XDH/SNCA/MMP9/RHOA/SIRT1/MAPT/MAPT/MAPT/VCP",26
"GO:0048017","BP","GO:0048017","inositol lipid-mediated signaling","24/173","219/21081",2.81575991166485e-20,1.51445112210936e-18,5.89790084095556e-19,"MAPK3/IGF1R/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SRC/ERBB2/HTR2A/PIK3CA/PIK3CG/MAPK1/AKT1/EGFR/INSR/PTK2/F2/RHOA/SIRT1/OGT",24
"GO:0019915","BP","GO:0019915","lipid storage","18/173","93/21081",4.94781889774664e-20,2.59681745408196e-18,1.01130842868708e-18,"PPARA/CES1/CES1/NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SREBF2/PPARG/IL6/NR1H2/SIRT1/STAT5B",18
"GO:0014065","BP","GO:0014065","phosphatidylinositol 3-kinase signaling","22/173","174/21081",4.95039335798161e-20,2.59681745408196e-18,1.01130842868708e-18,"MAPK3/IGF1R/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SRC/ERBB2/HTR2A/PIK3CA/PIK3CG/MAPK1/AKT1/EGFR/INSR/PTK2/F2/SIRT1",22
"GO:0032677","BP","GO:0032677","regulation of interleukin-8 production","19/173","112/21081",6.19795393436505e-20,3.21159832525818e-18,1.2507296001055e-18,"SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/TLR4/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/STAT3/ELANE/ELANE",19
"GO:1904999","BP","GO:1904999","positive regulation of leukocyte adhesion to arterial endothelial cell","10/173","12/21081",6.93101889594321e-20,3.54818063721237e-18,1.38180871330662e-18,"ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",10
"GO:0031663","BP","GO:0031663","lipopolysaccharide-mediated signaling pathway","17/173","79/21081",8.01980937305316e-20,4.05668690786939e-18,1.57984214717288e-18,"MAPK3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRKCA/MAPK1/NOS3/AKT1/TLR4/MIF/MIF/MAPK14",17
"GO:2000343","BP","GO:2000343","positive regulation of chemokine (C-X-C motif) ligand 2 production","11/173","17/21081",9.77317695567842e-20,4.88543869231501e-18,1.90259246740885e-18,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TLR4/MIF/MIF",11
"GO:0006869","BP","GO:0006869","lipid transport","30/173","427/21081",1.4582035334585e-19,7.17929524853445e-18,2.7959153561076e-18,"NPC1L1/CYP19A1/NR1H4/FABP4/FABP5/PPARA/FABP1/PTPN11/NOS2/CES1/CES1/NR1H3/SREBF2/DRD2/PPARG/AGTR1/NR1H2/DRD3/AKT1/MIF/MIF/AKR1C1/ACE/SIRT1/ABCC1/ABCC1/CFTR/ACACA/ACACA/CETP",30
"GO:0070920","BP","GO:0070920","regulation of production of small RNA involved in gene silencing by RNA","13/173","32/21081",1.46998984848787e-19,7.17929524853445e-18,2.7959153561076e-18,"ESR1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/IL6/EGFR/STAT3",13
"GO:0046883","BP","GO:0046883","regulation of hormone secretion","26/173","298/21081",2.24371430069004e-19,1.08335705268545e-17,4.21904172330711e-18,"CYP19A1/NR1H4/HMGCR/PTPN11/NOS2/ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/CNR1/IL6/AGTR1/PRKCA/HTR1A/EGFR/GLP1R/CD38/CFTR/DPP4",26
"GO:0006801","BP","GO:0006801","superoxide metabolic process","17/173","84/21081",2.47510515364456e-19,1.18165413458828e-17,4.60185133238231e-18,"NOS2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NQO1/NOS3/EGFR/MPO/NOX4/MAPT/MAPT/MAPT",17
"GO:1903829","BP","GO:1903829","positive regulation of cellular protein localization","28/173","366/21081",2.80521422000492e-19,1.32437280231121e-17,5.15765702204413e-18,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SREBF2/TERT/MAPK8/MDM2/PTGS2/SRC/GSK3B/ERBB2/CSNK2A2/MAPK1/AKT1/PARP1/EGFR/F2/MAPK14/CDK1/MAPT/MAPT/MAPT/PSEN1",28
"GO:0043491","BP","GO:0043491","protein kinase B signaling","26/173","301/21081",2.88539088481012e-19,1.34725559006134e-17,5.24677208897802e-18,"PTPN11/ESR1/IGF1R/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/DRD3/SRC/ERBB2/MTOR/PIK3CA/PIK3CG/AKT1/EGFR/XDH/INSR/PTK2/MC1R/SIRT1/NOX4",26
"GO:1904997","BP","GO:1904997","regulation of leukocyte adhesion to arterial endothelial cell","10/173","13/21081",2.98232047563762e-19,1.37538143572161e-17,5.35630579815529e-18,"ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",10
"GO:0019318","BP","GO:0019318","hexose metabolic process","25/173","271/21081",3.01036652205484e-19,1.37538143572161e-17,5.35630579815529e-18,"G6PD/FABP5/PPARA/RORA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SRC/GSK3B/MTOR/PIK3CA/AKT1/AKR1B1/INSR/PPP1CA/SIRT1/MAPK14/PFKFB3/OGT/EP300",25
"GO:0030522","BP","GO:0030522","intracellular receptor signaling pathway","26/173","302/21081",3.13576610744165e-19,1.41743299899145e-17,5.52007202788162e-18,"NR1H4/FABP5/PPARA/NR1I3/NR1I2/ESR1/ESR2/RORA/NR1H3/XIAP/PPARG/NR1H2/SRC/PIM1/CYP26A1/PARP1/TLR4/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/RHOA/SIRT1/STAT3/EP300",26
"GO:0031331","BP","GO:0031331","positive regulation of cellular catabolic process","30/173","441/21081",3.61510653021486e-19,1.61690396282978e-17,6.29689469861247e-18,"PPARA/FABP1/MAPK3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MDM2/IL6/GSK3B/HTR2A/AKT1/LRRK2/INSR/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/PTK2/SNCA/SIRT1/APP/PFKFB3/VCP/PSEN1",30
"GO:0019218","BP","GO:0019218","regulation of steroid metabolic process","20/173","144/21081",3.95193464879813e-19,1.74914274195242e-17,6.8118873551652e-18,"NR1H4/HMGCR/CES1/CES1/RORA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SREBF2/AGTR1/SIRT1/STAT5B/FASN/ACACA/ACACA",20
"GO:0035094","BP","GO:0035094","response to nicotine","15/173","57/21081",4.55010290981321e-19,1.99313270760787e-17,7.76208548478174e-18,"PPARA/SLC6A3/SLC6A3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/CNR1/MAPK1/CHRNA3",15
"GO:0060149","BP","GO:0060149","negative regulation of posttranscriptional gene silencing","13/173","35/21081",6.11619602869031e-19,2.62502191170759e-17,1.02229241436482e-17,"ESR1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/PPARG/IL6/STAT3",13
"GO:0060967","BP","GO:0060967","negative regulation of gene silencing by RNA","13/173","35/21081",6.11619602869031e-19,2.62502191170759e-17,1.02229241436482e-17,"ESR1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/PPARG/IL6/STAT3",13
"GO:0006694","BP","GO:0006694","steroid biosynthetic process","23/173","222/21081",6.50564422398388e-19,2.76424823077075e-17,1.07651291790554e-17,"NPC1L1/CYP19A1/G6PD/NR1H4/HMGCR/SRD5A1/CES1/CES1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SREBF2/AKR1B1/SIRT1/CFTR/FASN/ACACA/ACACA",23
"GO:1904994","BP","GO:1904994","regulation of leukocyte adhesion to vascular endothelial cell","14/173","46/21081",7.03303050512143e-19,2.95874718972881e-17,1.15225888004699e-17,"ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/RHOA/ELANE/ELANE",14
"GO:0048511","BP","GO:0048511","rhythmic process","26/173","315/21081",8.99881182240755e-19,3.74862268954997e-17,1.45986916252061e-17,"PPARA/SRD5A1/ESR1/NOS2/SERPINE1/RORA/NR1H3/MAPK8/DRD2/PPARG/DRD3/SRC/GSK3B/CSNK2A1/MTOR/CDK4/NOS3/EGFR/PPP1CA/MAPK10/SIRT1/STAT5B/MTNR1A/CDK1/OGT/EP300",26
"GO:0007252","BP","GO:0007252","I-kappaB phosphorylation","12/173","27/21081",9.90302318513384e-19,4.08523742850812e-17,1.59096090414209e-17,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IKBKB/CHUK/AKT1/TLR4",12
"GO:1903426","BP","GO:1903426","regulation of reactive oxygen species biosynthetic process","19/173","129/21081",1.00987125558659e-18,4.12590669710329e-17,1.60679920423292e-17,"ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTGS2/MTOR/AKT1/TLR4/HDAC4/INSR/SNCA/RHOA/STAT3",19
"GO:0031622","BP","GO:0031622","positive regulation of fever generation","10/173","14/21081",1.0364719007013e-18,4.15468783592435e-17,1.61800777348802e-17,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CNR1/PTGS2",10
"GO:0061757","BP","GO:0061757","leukocyte adhesion to arterial endothelial cell","10/173","14/21081",1.0364719007013e-18,4.15468783592435e-17,1.61800777348802e-17,"ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",10
"GO:0001774","BP","GO:0001774","microglial cell activation","16/173","75/21081",1.17428713631155e-18,4.61995003906275e-17,1.79920017376389e-17,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/LRRK2/SNCA/APP/MAPT/MAPT/MAPT/C5AR1",16
"GO:0002269","BP","GO:0002269","leukocyte activation involved in inflammatory response","16/173","75/21081",1.17428713631155e-18,4.61995003906275e-17,1.79920017376389e-17,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/LRRK2/SNCA/APP/MAPT/MAPT/MAPT/C5AR1",16
"GO:0060759","BP","GO:0060759","regulation of response to cytokine stimulus","23/173","230/21081",1.45012227393832e-18,5.65281609354487e-17,2.20144105710385e-17,"NR1H4/PTPN11/NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/IL6/NR1H2/IKBKB/CHUK/TLR4/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/MMP12",23
"GO:0002534","BP","GO:0002534","cytokine production involved in inflammatory response","17/173","93/21081",1.56856259595329e-18,6.05892951836867e-17,2.35959846970199e-17,"NOS2/ALOX5/ALOX5/IDO1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/TLR4/F2/STAT3/MAPK14",17
"GO:0006006","BP","GO:0006006","glucose metabolic process","23/173","231/21081",1.59940342300039e-18,6.12240103092671e-17,2.3843169093946e-17,"G6PD/FABP5/PPARA/RORA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SRC/GSK3B/MTOR/PIK3CA/AKT1/INSR/PPP1CA/SIRT1/MAPK14/OGT/EP300",23
"GO:0009914","BP","GO:0009914","hormone transport","27/173","356/21081",1.61410307744089e-18,6.12350355004136e-17,2.38474627606868e-17,"CYP19A1/NR1H4/HMGCR/PTPN11/NOS2/ALOX5/ALOX5/TTR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/CNR1/IL6/AGTR1/PRKCA/HTR1A/EGFR/GLP1R/CD38/CFTR/DPP4",27
"GO:0050796","BP","GO:0050796","regulation of insulin secretion","22/173","204/21081",1.64493303453491e-18,6.18523934844145e-17,2.40878875667339e-17,"NR1H4/HMGCR/PTPN11/NOS2/ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/CNR1/IL6/PRKCA/GLP1R/CD38/CFTR/DPP4",22
"GO:2001236","BP","GO:2001236","regulation of extrinsic apoptotic signaling pathway","21/173","181/21081",2.23637968264743e-18,8.33541865927098e-17,3.24615776650208e-17,"SERPINE1/BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/SRC/GSK3B/NOS3/AKT1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/PPP1CA",21
"GO:0061043","BP","GO:0061043","regulation of vascular wound healing","11/173","21/21081",2.70766114418299e-18,9.91797603589099e-17,3.8624712510487e-17,"ALOX5/ALOX5/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",11
"GO:1903799","BP","GO:1903799","negative regulation of production of miRNAs involved in gene silencing by miRNA","11/173","21/21081",2.70766114418299e-18,9.91797603589099e-17,3.8624712510487e-17,"ESR1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/STAT3",11
"GO:0043154","BP","GO:0043154","negative regulation of cysteine-type endopeptidase activity involved in apoptotic process","17/173","96/21081",2.7749240401968e-18,1.00774805528173e-16,3.92458892594635e-17,"FABP1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MDM2/XIAP/PTGS2/SRC/CSNK2A1/AKT1/SNCA/MMP9",17
"GO:0090276","BP","GO:0090276","regulation of peptide hormone secretion","23/173","237/21081",2.85098681028596e-18,1.02659686075467e-16,3.99799399265793e-17,"NR1H4/HMGCR/PTPN11/NOS2/ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/CNR1/IL6/PRKCA/EGFR/GLP1R/CD38/CFTR/DPP4",23
"GO:0015850","BP","GO:0015850","organic hydroxy compound transport","25/173","298/21081",2.99080546643224e-18,1.06789348124963e-16,4.15882016208003e-17,"NPC1L1/CYP19A1/NR1H4/PTPN11/SLC6A3/SLC6A3/CES1/CES1/NR1H3/SREBF2/DRD2/CNR1/PPARG/AGTR1/NR1H2/DRD3/HTR1A/HTR2A/NOS1/AKR1C1/SNCA/SIRT1/MAOB/CFTR/CETP",25
"GO:0031620","BP","GO:0031620","regulation of fever generation","10/173","15/21081",3.08755010319638e-18,1.09325003237345e-16,4.2575690896708e-17,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CNR1/PTGS2",10
"GO:0002532","BP","GO:0002532","production of molecular mediator involved in inflammatory response","18/173","116/21081",3.25068471265417e-18,1.14150077223699e-16,4.44547748437787e-17,"NOS2/ALOX5/ALOX5/IDO1/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/TLR4/F2/STAT3/MAPK14",18
"GO:0032147","BP","GO:0032147","activation of protein kinase activity","27/173","366/21081",3.27776854702304e-18,1.14157693084434e-16,4.44577407758431e-17,"MAPK3/PTPN11/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/SRC/MTOR/PIK3CA/MAPK1/AKT1/CHRNA3/TLR4/LRRK2/EGFR/INSR/MAPK10/ABL1/MAPK14/CDK1/C5AR1/PSEN1",27
"GO:0010803","BP","GO:0010803","regulation of tumor necrosis factor-mediated signaling pathway","16/173","80/21081",3.57431371618517e-18,1.23473650244478e-16,4.8085760905803e-17,"NR1H4/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IKBKB/CHUK/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",16
"GO:0009895","BP","GO:0009895","negative regulation of catabolic process","27/173","368/21081",3.76667398974665e-18,1.29069336955109e-16,5.02649534115597e-17,"PPARA/HMGCR/NOS2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CNR1/CSNK2A1/CSNK2A2/MTOR/PIK3CA/PIK3CG/AKT1/LRRK2/EGFR/HDAC4/PTK2/SNCA/STAT3/MAPK14/OGT/PSEN1",27
"GO:0033138","BP","GO:0033138","positive regulation of peptidyl-serine phosphorylation","18/173","117/21081",3.8148701097221e-18,1.29675064769674e-16,5.05008489472264e-17,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTGS2/IL6/PIK3CA/AKT1/NOS1/EGFR/MIF/MIF/SNCA/APP",18
"GO:1904645","BP","GO:1904645","response to amyloid-beta","15/173","65/21081",4.04274903063257e-18,1.36330481199665e-16,5.30927441616909e-17,"BACE1/IGF1R/GSK3B/PARP1/TLR4/MMP3/MMP9/MMP2/ABCC1/ABCC1/MMP13/APP/MMP12/CACNA1B/PSEN1",15
"GO:0051091","BP","GO:0051091","positive regulation of DNA-binding transcription factor activity","26/173","335/21081",4.15230567796268e-18,1.38922415950106e-16,5.41021510630529e-17,"ESR1/ESR2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/IL6/PRKCB/IKBKB/CHUK/AKT1/TLR4/HDAC4/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/STAT3/APP/EP300",26
"GO:0045598","BP","GO:0045598","regulation of fat cell differentiation","20/173","162/21081",4.31576561708214e-18,1.43263188335797e-16,5.57926278787264e-17,"ALOX5/ALOX5/RORA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/PTGS2/IL6/HTR2A/MTOR/PIM1/AKT1/SIRT1/MAPK14",20
"GO:1903798","BP","GO:1903798","regulation of production of miRNAs involved in gene silencing by miRNA","12/173","30/21081",4.82370435996113e-18,1.58883099422286e-16,6.18756691461355e-17,"ESR1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/EGFR/STAT3",12
"GO:0051897","BP","GO:0051897","positive regulation of protein kinase B signaling","21/173","189/21081",5.53226308944603e-18,1.80819891285047e-16,7.04187658025033e-17,"PTPN11/ESR1/IGF1R/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SRC/ERBB2/MTOR/PIK3CA/PIK3CG/EGFR/INSR/PTK2/MC1R/NOX4",21
"GO:0001959","BP","GO:0001959","regulation of cytokine-mediated signaling pathway","22/173","216/21081",5.69546319190604e-18,1.84733000781746e-16,7.19426929503921e-17,"NR1H4/PTPN11/NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/IL6/NR1H2/IKBKB/CHUK/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/MMP12",22
"GO:0043467","BP","GO:0043467","regulation of generation of precursor metabolites and energy","20/173","165/21081",6.24343784872947e-18,2.00972480448875e-16,7.82670199218719e-17,"PPARA/NOS2/GSK3B/HTR2A/MTOR/PIK3CA/AKT1/HDAC4/INSR/SNCA/PPP1CA/RHOA/STAT3/CDK1/APP/PFKFB3/OGT/VCP/EP300/PSEN1",20
"GO:0051966","BP","GO:0051966","regulation of synaptic transmission, glutamatergic","16/173","83/21081",6.71203533633146e-18,2.14431865744905e-16,8.35086628311282e-17,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/CNR1/PTGS2/DRD3/HTR2A/LRRK2/EGFR/PSEN1",16
"GO:1903347","BP","GO:1903347","negative regulation of bicellular tight junction assembly","9/173","11/21081",7.42168006538415e-18,2.35333720879233e-16,9.1648712197831e-17,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IKBKB",9
"GO:0045639","BP","GO:0045639","positive regulation of myeloid cell differentiation","18/173","122/21081",8.30258161339182e-18,2.6131606870594e-16,1.01767316150113e-16,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRKCA/PRMT1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/STAT5B/STAT3/MAPK14",18
"GO:0019932","BP","GO:0019932","second-messenger-mediated signaling","30/173","494/21081",8.51845714743898e-18,2.64196528609257e-16,1.02889086713593e-16,"NOS2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/CNR1/PDE4A/CXCR3/AGTR1/DRD3/GSK3B/PRKCA/MTOR/NOS3/NOS1/LRRK2/EGFR/HDAC4/MC1R/CXCL8/GLP1R/MAPT/MAPT/MAPT/PPP2CA",30
"GO:0048732","BP","GO:0048732","gland development","30/173","494/21081",8.51845714743898e-18,2.64196528609257e-16,1.02889086713593e-16,"CYP19A1/SRD5A1/MAPK3/ESR1/SLC6A3/SLC6A3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/IL6/SRC/CSNK2A2/PIK3CA/MAPK1/AKT1/EGFR/XDH/CCND1/INSR/STAT5B/ABL1/TYR/FASN/PSEN1",30
"GO:0097305","BP","GO:0097305","response to alcohol","23/173","250/21081",9.44396306972071e-18,2.90778254226401e-16,1.13241113238756e-16,"G6PD/HMGCR/SLC6A3/SLC6A3/CES1/CES1/BCL2L1/DRD2/CNR1/PPARG/CDK4/NQO1/AKT1/PARP1/CCND1/RHOA/MAOB/STAT3/CDK1/CFTR/IL2/ACACA/ACACA",23
"GO:0046879","BP","GO:0046879","hormone secretion","26/173","347/21081",9.89635756234898e-18,3.02515275413099e-16,1.17811996122776e-16,"CYP19A1/NR1H4/HMGCR/PTPN11/NOS2/ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/CNR1/IL6/AGTR1/PRKCA/HTR1A/EGFR/GLP1R/CD38/CFTR/DPP4",26
"GO:0072567","BP","GO:0072567","chemokine (C-X-C motif) ligand 2 production","11/173","23/21081",1.02335863913836e-17,3.08386585652403e-16,1.20098527863046e-16,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TLR4/MIF/MIF",11
"GO:2000341","BP","GO:2000341","regulation of chemokine (C-X-C motif) ligand 2 production","11/173","23/21081",1.02335863913836e-17,3.08386585652403e-16,1.20098527863046e-16,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TLR4/MIF/MIF",11
"GO:0050994","BP","GO:0050994","regulation of lipid catabolic process","15/173","69/21081",1.07434061015529e-17,3.21469947362663e-16,1.25193731591113e-16,"PPARA/FABP1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CNR1/MTOR/PIK3CG/CDK4/AKT1",15
"GO:0014066","BP","GO:0014066","regulation of phosphatidylinositol 3-kinase signaling","19/173","146/21081",1.1165896432692e-17,3.31775482115443e-16,1.29207134281869e-16,"MAPK3/IGF1R/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SRC/PIK3CA/PIK3CG/MAPK1/EGFR/INSR/PTK2/F2/SIRT1",19
"GO:0005996","BP","GO:0005996","monosaccharide metabolic process","25/173","315/21081",1.12853861376087e-17,3.32997261796522e-16,1.29682945967257e-16,"G6PD/FABP5/PPARA/RORA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SRC/GSK3B/MTOR/PIK3CA/AKT1/AKR1B1/INSR/PPP1CA/SIRT1/MAPK14/PFKFB3/OGT/EP300",25
"GO:0050890","BP","GO:0050890","cognition","26/173","349/21081",1.13997213043831e-17,3.34051143602234e-16,1.30093371255828e-16,"HMGCR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/CNR1/PTGS2/DRD3/HTR2A/MTOR/MAPK1/EGFR/INSR/GLP1R/APP/MAPT/MAPT/MAPT/C5AR1/EP300/PSEN1",26
"GO:0060965","BP","GO:0060965","negative regulation of gene silencing by miRNA","12/173","32/21081",1.24153819046046e-17,3.61321628168937e-16,1.40713629084631e-16,"ESR1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/IL6/STAT3",12
"GO:2000117","BP","GO:2000117","negative regulation of cysteine-type endopeptidase activity","17/173","105/21081",1.36997703958935e-17,3.95988601443207e-16,1.54214386411347e-16,"FABP1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MDM2/XIAP/PTGS2/SRC/CSNK2A1/AKT1/SNCA/MMP9",17
"GO:0050730","BP","GO:0050730","regulation of peptidyl-tyrosine phosphorylation","24/173","286/21081",1.47496511990423e-17,4.23454513140072e-16,1.64910751670658e-16,"PTPN11/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/SRC/HTR2A/MTOR/EGFR/MIF/MIF/ACE/ABL1/STAT3/NOX4/APP/IL2/PPP2CA/PSEN1",24
"GO:0042180","BP","GO:0042180","cellular ketone metabolic process","24/173","287/21081",1.59853131291064e-17,4.55849634131362e-16,1.77526755485378e-16,"CYP19A1/AKR1B10/NR1H4/FABP5/PPARA/HMGCR/SRD5A1/FABP1/CES1/CES1/IDO1/NR1H3/CNR1/PPARG/PTGS2/NR1H2/MTOR/NQO1/AKT1/AKR1B1/AKR1C1/SIRT1/STAT5B/GLO1",24
"GO:0002687","BP","GO:0002687","positive regulation of leukocyte migration","20/173","174/21081",1.80932966558688e-17,5.1252278327191e-16,1.99597630477374e-16,"MAPK3/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/MAPK1/PTK2/RHOA/CXCL8/MAPK14/APP/C5AR1/ELANE/ELANE",20
"GO:0001660","BP","GO:0001660","fever generation","10/173","17/21081",1.97153379807618e-17,5.5477133165733e-16,2.16050967624661e-16,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CNR1/PTGS2",10
"GO:0006631","BP","GO:0006631","fatty acid metabolic process","28/173","433/21081",2.3339068065567e-17,6.52419080332856e-16,2.54079051240106e-16,"FABP5/PPARA/FABP1/MAPK3/PTGS1/CES1/CES1/ALOX5/ALOX5/NR1H3/CNR1/PPARG/PTGS2/NR1H2/MTOR/AKT1/MIF/MIF/AKR1C1/CBR1/SIRT1/MAPK14/EPHX1/CYP1B1/FASN/MGLL/ACACA/ACACA",28
"GO:0010952","BP","GO:0010952","positive regulation of peptidase activity","22/173","231/21081",2.42179170156368e-17,6.72561630061704e-16,2.61923395587073e-16,"CTSD/MAPK3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/XDH/SNCA/RHOA/SIRT1/STAT3/MAPK14/APP/MAPT/MAPT/MAPT/VCP",22
"GO:0042493","BP","GO:0042493","response to drug","28/173","434/21081",2.47802283343165e-17,6.83709027224097e-16,2.66264654419314e-16,"NPC1L1/SRD5A1/NR1I2/SLC6A3/SLC6A3/NOS2/DRD2/MDM2/PDE4A/PPARG/PTGS2/DRD3/SRC/HTR2A/CHEK2/CDK4/CHUK/NOS1/EGFR/HDAC4/CCND1/RHOA/MAOB/STAT3/ABCC1/ABCC1/CDK1/CD38",28
"GO:0046165","BP","GO:0046165","alcohol biosynthetic process","20/173","177/21081",2.54448425282302e-17,6.97517005822259e-16,2.71642054019544e-16,"NPC1L1/G6PD/HMGCR/CES1/CES1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SREBF2/AKR1B1/SNCA/CFTR/FASN/ACACA/ACACA",20
"GO:0050810","BP","GO:0050810","regulation of steroid biosynthetic process","17/173","109/21081",2.65199937813731e-17,7.17862406598113e-16,2.79565396978171e-16,"NR1H4/HMGCR/CES1/CES1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SREBF2/SIRT1/FASN/ACACA/ACACA",17
"GO:1900015","BP","GO:1900015","regulation of cytokine production involved in inflammatory response","16/173","90/21081",2.65249230020955e-17,7.17862406598113e-16,2.79565396978171e-16,"NOS2/ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/TLR4/F2/STAT3/MAPK14",16
"GO:0045444","BP","GO:0045444","fat cell differentiation","23/173","263/21081",2.92167142242104e-17,7.85707713535887e-16,3.05987173620645e-16,"FABP4/ALOX5/ALOX5/RORA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/PTGS2/IL6/HTR2A/MTOR/PIM1/AKT1/CCND1/SIRT1/MAPK14/EP300",23
"GO:0035509","BP","GO:0035509","negative regulation of myosin-light-chain-phosphatase activity","9/173","12/21081",2.94787896946585e-17,7.87769669261659e-16,3.06790184707071e-16,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IKBKB",9
"GO:0031098","BP","GO:0031098","stress-activated protein kinase signaling cascade","25/173","329/21081",3.17347836512777e-17,8.42756848339243e-16,3.28204473025056e-16,"HMGCR/MAPK3/IGF1R/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MAPK8/PRMT1/IKBKB/MAPK1/CHUK/AKT1/TLR4/EGFR/XDH/AKR1B1/RHOA/MAPK10/MAPK14/APP",25
"GO:0070374","BP","GO:0070374","positive regulation of ERK1 and ERK2 cascade","23/173","266/21081",3.75775579950524e-17,9.91720769695514e-16,3.86217202799754e-16,"HMGCR/MAPK3/PTPN11/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/SRC/PRKCA/HTR2A/TLR4/EGFR/MIF/MIF/ABL1/NOX4/APP/C5AR1",23
"GO:0031652","BP","GO:0031652","positive regulation of heat generation","10/173","18/21081",4.40475865696095e-17,1.1552975020634e-15,4.49920767299715e-16,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CNR1/PTGS2",10
"GO:0030073","BP","GO:0030073","insulin secretion","22/173","238/21081",4.59108283475317e-17,1.19677981379547e-15,4.66075700111849e-16,"NR1H4/HMGCR/PTPN11/NOS2/ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/CNR1/IL6/PRKCA/GLP1R/CD38/CFTR/DPP4",22
"GO:1990748","BP","GO:1990748","cellular detoxification","18/173","134/21081",4.67528025874447e-17,1.2112966963052e-15,4.71729176299506e-16,"AKR1B10/FABP1/PTGS1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTGS2/NQO1/NOS3/PIM1/GSR/MPO/ABCG2",18
"GO:0042176","BP","GO:0042176","regulation of protein catabolic process","28/173","451/21081",6.70170262837088e-17,1.72578996775442e-15,6.72094196605998e-16,"HMGCR/NOS2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MDM2/GSK3B/CSNK2A1/CSNK2A2/CHEK2/AKT1/LRRK2/EGFR/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/PTK2/SNCA/OGT/VCP/PSEN1",28
"GO:0070371","BP","GO:0070371","ERK1 and ERK2 cascade","26/173","376/21081",7.05891321669901e-17,1.80682664203338e-15,7.03653238849134e-16,"HMGCR/MAPK3/PTPN11/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/SRC/ERBB2/PRKCA/HTR2A/CSK/MAPK1/TLR4/EGFR/MIF/MIF/ABL1/NOX4/APP/C5AR1",26
"GO:0060969","BP","GO:0060969","negative regulation of gene silencing","13/173","48/21081",7.29000462776847e-17,1.85480417146037e-15,7.22337678843495e-16,"ESR1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/PPARG/IL6/STAT3",13
"GO:0061756","BP","GO:0061756","leukocyte adhesion to vascular endothelial cell","14/173","62/21081",7.61354688106463e-17,1.92559289866926e-15,7.49905745428171e-16,"ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/RHOA/ELANE/ELANE",14
"GO:0048545","BP","GO:0048545","response to steroid hormone","26/173","378/21081",8.03133538195455e-17,2.0192392921849e-15,7.86375535374186e-16,"PPARA/SRD5A1/ESR1/ESR2/NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MDM2/PTGS2/IL6/SRC/PARP1/EGFR/CCND1/RHOA/SIRT1/MAOB/ESRRA/CD38/EP300",26
"GO:0051235","BP","GO:0051235","maintenance of location","25/173","344/21081",9.10109883218862e-17,2.27473934929232e-15,8.85877855368453e-16,"PPARA/CES1/CES1/NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SREBF2/DRD2/PPARG/IL6/NR1H2/HTR2A/AKT1/NOS1/SNCA/F2/SIRT1/STAT5B/ABL1",25
"GO:0071803","BP","GO:0071803","positive regulation of podosome assembly","10/173","19/21081",9.23354843531111e-17,2.29434779541736e-15,8.93514197618286e-16,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SRC/RHOA",10
"GO:1903721","BP","GO:1903721","positive regulation of I-kappaB phosphorylation","9/173","13/21081",9.51350444006224e-17,2.35016746312933e-15,9.15252691540872e-16,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/AKT1",9
"GO:0006066","BP","GO:0006066","alcohol metabolic process","27/173","423/21081",1.26830640859817e-16,3.1150485145281e-15,1.21312909906682e-15,"NPC1L1/AKR1B10/G6PD/NR1H4/HMGCR/CES1/CES1/TTR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SREBF2/AKR1B1/AKR1C1/SNCA/CYP1B1/APP/CFTR/FASN/ACACA/ACACA/CETP",27
"GO:0007568","BP","GO:0007568","aging","26/173","386/21081",1.33547104803907e-16,3.26115889834368e-15,1.27003054296274e-15,"HMGCR/MAPK3/SLC6A3/SLC6A3/SERPINE1/TERT/CNR1/PTGS2/HTR2A/CHEK2/MTOR/NQO1/MAPK1/AKT1/LRRK2/MIF/MIF/MPO/SIRT1/ABL1/STAT3/MAPK14/NOX4/CDK1/APP/PSEN1",26
"GO:0097237","BP","GO:0097237","cellular response to toxic substance","18/173","142/21081",1.34673921707479e-16,3.26988281905758e-15,1.2734279995438e-15,"AKR1B10/FABP1/PTGS1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTGS2/NQO1/NOS3/PIM1/GSR/MPO/ABCG2",18
"GO:0021782","BP","GO:0021782","glial cell development","18/173","143/21081",1.52989585384396e-16,3.69348152442215e-15,1.43839490564755e-15,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/AKT1/TLR4/EGFR/APP/MAPT/MAPT/MAPT/C5AR1/PSEN1",18
"GO:0014068","BP","GO:0014068","positive regulation of phosphatidylinositol 3-kinase signaling","16/173","100/21081",1.54977865357244e-16,3.6994435387805e-15,1.44071676133405e-15,"IGF1R/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SRC/PIK3CA/PIK3CG/INSR/PTK2/F2/SIRT1",16
"GO:1900407","BP","GO:1900407","regulation of cellular response to oxidative stress","16/173","100/21081",1.54977865357244e-16,3.6994435387805e-15,1.44071676133405e-15,"ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/AKT1/PARP1/TLR4/LRRK2/MMP3/SIRT1",16
"GO:0001659","BP","GO:0001659","temperature homeostasis","20/173","195/21081",1.73221707025379e-16,4.11183817402702e-15,1.60132033780592e-15,"FABP4/FABP5/IGF1R/NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/CNR1/PTGS2/NR1H2/HTR2A/TLR4/STAT3/OGT",20
"GO:0031650","BP","GO:0031650","regulation of heat generation","10/173","20/21081",1.83372454915115e-16,4.32860867185736e-15,1.68573976097404e-15,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CNR1/PTGS2",10
"GO:0030072","BP","GO:0030072","peptide hormone secretion","23/173","287/21081",2.00870137289458e-16,4.71545421736413e-15,1.83639346216358e-15,"NR1H4/HMGCR/PTPN11/NOS2/ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/CNR1/IL6/PRKCA/EGFR/GLP1R/CD38/CFTR/DPP4",23
"GO:0061041","BP","GO:0061041","regulation of wound healing","19/173","170/21081",2.03607763861951e-16,4.75345817939248e-15,1.85119378132439e-15,"PLG/HMGCR/ALOX5/ALOX5/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRKCA/MTOR/NOS3/TLR4/PTK2/F2",19
"GO:0070372","BP","GO:0070372","regulation of ERK1 and ERK2 cascade","25/173","357/21081",2.17562656102569e-16,5.05149576928861e-15,1.96726198097923e-15,"HMGCR/MAPK3/PTPN11/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/SRC/ERBB2/PRKCA/HTR2A/CSK/TLR4/EGFR/MIF/MIF/ABL1/NOX4/APP/C5AR1",25
"GO:0002573","BP","GO:0002573","myeloid leukocyte differentiation","22/173","257/21081",2.35316884882556e-16,5.43402958622817e-15,2.1162365162207e-15,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/SRC/PRKCA/MTOR/PARP1/TLR4/MMP9/SIRT1/MAPK14/ESRRA/GLO1/APP/FASN/PSEN1",22
"GO:0007623","BP","GO:0007623","circadian rhythm","21/173","227/21081",2.42983583007035e-16,5.58074186052374e-15,2.17337236123504e-15,"PPARA/SRD5A1/NOS2/SERPINE1/RORA/NR1H3/MAPK8/DRD2/PPARG/DRD3/GSK3B/MTOR/CDK4/EGFR/PPP1CA/MAPK10/SIRT1/MTNR1A/CDK1/OGT/EP300",21
"GO:0097191","BP","GO:0097191","extrinsic apoptotic signaling pathway","22/173","258/21081",2.55475709029207e-16,5.83610907346828e-15,2.27282294620211e-15,"SERPINE1/BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/SRC/GSK3B/NOS3/AKT1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/PPP1CA/IL2",22
"GO:0050714","BP","GO:0050714","positive regulation of protein secretion","20/173","199/21081",2.58203456880783e-16,5.86687961650507e-15,2.28480627197631e-15,"NR1H4/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/IL6/NR1H2/SRC/TLR4/EGFR/MIF/MIF/CD38/CFTR/IL2",20
"GO:0035507","BP","GO:0035507","regulation of myosin-light-chain-phosphatase activity","9/173","14/21081",2.64512474900477e-16,5.97826332900067e-15,2.32818370965033e-15,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IKBKB",9
"GO:0043434","BP","GO:0043434","response to peptide hormone","28/173","478/21081",2.98615417549758e-16,6.71331697972975e-15,2.61444409015996e-15,"NR1H4/PPARA/SRD5A1/PTPN11/IGF1R/MDM2/PPARG/PTGS2/AGTR1/PRKCB/SRC/GSK3B/CSK/MTOR/PIK3CA/CDK4/CCNA2/CHUK/AKT1/PARP1/INSR/PTK2/SIRT1/STAT5B/GLP1R/STAT3/ESRRA/OGT",28
"GO:0045765","BP","GO:0045765","regulation of angiogenesis","27/173","438/21081",3.02239161205803e-16,6.75902208401818e-15,2.6322435535486e-15,"ALOX5/ALOX5/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/PPARG/PTGS2/IL6/AGTR1/PRKCB/ERBB2/PRKCA/NOS3/RHOA/CXCL8/SIRT1/ABL1/STAT3/CYP1B1/C5AR1",27
"GO:0050673","BP","GO:0050673","epithelial cell proliferation","28/173","479/21081",3.15010080053843e-16,6.97123869869155e-15,2.7148895057272e-15,"ESR1/ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/IL6/AGTR1/ERBB2/PRKCA/MTOR/MAPK1/AKT1/TLR4/EGFR/XDH/CCND1/SIRT1/STAT3/MMP12/C5AR1/PSEN1",28
"GO:1901342","BP","GO:1901342","regulation of vasculature development","28/173","479/21081",3.15010080053843e-16,6.97123869869155e-15,2.7148895057272e-15,"ALOX5/ALOX5/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/PPARG/PTGS2/IL6/AGTR1/PRKCB/ERBB2/PRKCA/NOS3/XDH/RHOA/CXCL8/SIRT1/ABL1/STAT3/CYP1B1/C5AR1",28
"GO:0034612","BP","GO:0034612","response to tumor necrosis factor","26/173","403/21081",3.78403005250849e-16,8.3307480275174e-15,3.24433882876648e-15,"NR1H4/FABP4/MAPK3/RORA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTGS2/IKBKB/MAPK1/CHUK/AKT1/HDAC4/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/CXCL8/SIRT1/MAPK14",26
"GO:1902893","BP","GO:1902893","regulation of pri-miRNA transcription by RNA polymerase II","14/173","69/21081",3.85231579058e-16,8.43736587328579e-15,3.28586024025598e-15,"PPARA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SREBF2/TERT/PPARG/HDAC4/STAT3",14
"GO:0061042","BP","GO:0061042","vascular wound healing","11/173","30/21081",3.93491949272743e-16,8.57408867928147e-15,3.33910577196628e-15,"ALOX5/ALOX5/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",11
"GO:0150077","BP","GO:0150077","regulation of neuroinflammatory response","13/173","54/21081",4.01323697495807e-16,8.70012444214125e-15,3.38818932579704e-15,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTGS2/IL6/LRRK2/MMP3/MMP9",13
"GO:1901889","BP","GO:1901889","negative regulation of cell junction assembly","12/173","41/21081",4.07505894316917e-16,8.78930225864254e-15,3.42291886650384e-15,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SRC/IKBKB/PTK2/ACE",12
"GO:0002526","BP","GO:0002526","acute inflammatory response","17/173","128/21081",4.37202772524691e-16,9.38219485079502e-15,3.65381583417764e-15,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CNR1/PPARG/PTGS2/IL6/PIK3CG/F2/STAT3/ELANE/ELANE",17
"GO:0035249","BP","GO:0035249","synaptic transmission, glutamatergic","16/173","107/21081",4.75237771347388e-16,1.01471622635932e-14,3.95172587441467e-15,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/CNR1/PTGS2/DRD3/HTR2A/LRRK2/EGFR/PSEN1",16
"GO:0010827","BP","GO:0010827","regulation of glucose transmembrane transport","15/173","88/21081",5.25838448500463e-16,1.11714378383923e-14,4.35062126864593e-15,"FABP5/PTPN11/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/PRKCB/AKT1/INSR/MAPK14",15
"GO:0071356","BP","GO:0071356","cellular response to tumor necrosis factor","25/173","372/21081",5.69062600499065e-16,1.20295870125399e-14,4.6848201517912e-15,"NR1H4/FABP4/MAPK3/RORA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IKBKB/MAPK1/CHUK/AKT1/HDAC4/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/CXCL8/SIRT1/MAPK14",25
"GO:0061614","BP","GO:0061614","pri-miRNA transcription by RNA polymerase II","14/173","71/21081",5.91386108848547e-16,1.24396018638489e-14,4.84449694168794e-15,"PPARA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SREBF2/TERT/PPARG/HDAC4/STAT3",14
"GO:0050995","BP","GO:0050995","negative regulation of lipid catabolic process","11/173","31/21081",6.05614415302417e-16,1.26761362099506e-14,4.93661322714753e-15,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CNR1/PIK3CG/AKT1",11
"GO:0051341","BP","GO:0051341","regulation of oxidoreductase activity","17/173","131/21081",6.51805465436982e-16,1.35442003109107e-14,5.27467339404976e-15,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/CNR1/AGTR1/NOS3/AKT1/LRRK2/EGFR/SNCA/ABL1",17
"GO:0043280","BP","GO:0043280","positive regulation of cysteine-type endopeptidase activity involved in apoptotic process","18/173","155/21081",6.56260643274132e-16,1.35442003109107e-14,5.27467339404976e-15,"CTSD/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/XDH/SNCA/RHOA/SIRT1/MAPT/MAPT/MAPT/VCP",18
"GO:1903719","BP","GO:1903719","regulation of I-kappaB phosphorylation","9/173","15/21081",6.56649862096398e-16,1.35442003109107e-14,5.27467339404976e-15,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/AKT1",9
"GO:0045637","BP","GO:0045637","regulation of myeloid cell differentiation","23/173","304/21081",7.06743404708664e-16,1.45070180029329e-14,5.64963453954752e-15,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRKCB/PRKCA/PRMT1/MTOR/TLR4/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/STAT5B/STAT3/MAPK14/ESRRA/EP300",23
"GO:0071675","BP","GO:0071675","regulation of mononuclear cell migration","14/173","72/21081",7.28959560942344e-16,1.48911018002116e-14,5.79921270142392e-15,"MAPK3/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MAPK1/PTK2/MAPK14/C5AR1",14
"GO:0033135","BP","GO:0033135","regulation of peptidyl-serine phosphorylation","18/173","156/21081",7.36670482241497e-16,1.49766166461441e-14,5.83251572945672e-15,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTGS2/IL6/PIK3CA/AKT1/NOS1/EGFR/MIF/MIF/SNCA/APP",18
"GO:1902882","BP","GO:1902882","regulation of response to oxidative stress","16/173","110/21081",7.4914745769041e-16,1.51577502272693e-14,5.90305665909436e-15,"ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/AKT1/PARP1/TLR4/LRRK2/MMP3/SIRT1",16
"GO:0006447","BP","GO:0006447","regulation of translational initiation by iron","8/173","10/21081",7.75592423683248e-16,1.52723312613498e-14,5.94767926641363e-15,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0010693","BP","GO:0010693","negative regulation of alkaline phosphatase activity","8/173","10/21081",7.75592423683248e-16,1.52723312613498e-14,5.94767926641363e-15,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0032603","BP","GO:0032603","fractalkine production","8/173","10/21081",7.75592423683248e-16,1.52723312613498e-14,5.94767926641363e-15,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0060557","BP","GO:0060557","positive regulation of vitamin D biosynthetic process","8/173","10/21081",7.75592423683248e-16,1.52723312613498e-14,5.94767926641363e-15,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0060559","BP","GO:0060559","positive regulation of calcidiol 1-monooxygenase activity","8/173","10/21081",7.75592423683248e-16,1.52723312613498e-14,5.94767926641363e-15,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0051047","BP","GO:0051047","positive regulation of secretion","25/173","377/21081",7.76376453860099e-16,1.52723312613498e-14,5.94767926641363e-15,"CYP19A1/NR1H4/PTPN11/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/CNR1/IL6/NR1H2/DRD3/SRC/TLR4/EGFR/MIF/MIF/SNCA/CD38/CFTR/IL2",25
"GO:0050715","BP","GO:0050715","positive regulation of cytokine secretion","12/173","43/21081",7.8022519059736e-16,1.5277312602987e-14,5.94961920746568e-15,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/SRC/MIF/MIF",12
"GO:0006953","BP","GO:0006953","acute-phase response","13/173","57/21081",8.68013955516461e-16,1.69183087017864e-14,6.58869115437893e-15,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CNR1/PTGS2/IL6/F2/STAT3",13
"GO:0019430","BP","GO:0019430","removal of superoxide radicals","11/173","32/21081",9.16337718510798e-16,1.77786254153077e-14,6.92373416726256e-15,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NQO1/NOS3/MPO",11
"GO:0098754","BP","GO:0098754","detoxification","18/173","158/21081",9.25954718563768e-16,1.78835527235339e-14,6.96459721331217e-15,"AKR1B10/FABP1/PTGS1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTGS2/NQO1/NOS3/PIM1/GSR/MPO/ABCG2",18
"GO:0016042","BP","GO:0016042","lipid catabolic process","25/173","380/21081",9.33331184482734e-16,1.79444534066386e-14,6.98831446538156e-15,"CYP19A1/AKR1B10/FABP4/FABP5/PPARA/SRD5A1/FABP1/CES1/CES1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CNR1/MTOR/PIK3CG/CDK4/CYP26A1/AKT1/CYP1B1/MGLL",25
"GO:0002675","BP","GO:0002675","positive regulation of acute inflammatory response","12/173","44/21081",1.06524205034976e-15,2.02969213988167e-14,7.90446307835647e-15,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CNR1/PTGS2/IL6/PIK3CG",12
"GO:0097242","BP","GO:0097242","amyloid-beta clearance","12/173","44/21081",1.06524205034976e-15,2.02969213988167e-14,7.90446307835647e-15,"HMGCR/IGF1R/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/INSR/C5AR1",12
"GO:0071801","BP","GO:0071801","regulation of podosome assembly","10/173","23/21081",1.11171468376202e-15,2.10878379076108e-14,8.21247877290365e-15,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SRC/RHOA",10
"GO:0050731","BP","GO:0050731","positive regulation of peptidyl-tyrosine phosphorylation","20/173","215/21081",1.16981240133697e-15,2.20912573034702e-14,8.60325190597298e-15,"PTPN11/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/SRC/HTR2A/MTOR/MIF/MIF/ACE/ABL1/STAT3/NOX4/IL2",20
"GO:0015718","BP","GO:0015718","monocarboxylic acid transport","19/173","187/21081",1.21975014206809e-15,2.29323820957845e-14,8.9308207886867e-15,"NR1H4/FABP4/FABP5/PPARA/FABP1/NOS2/CES1/CES1/DRD2/PPARG/DRD3/AKT1/MIF/MIF/AKR1C1/ACE/ABCG2/ACACA/ACACA",19
"GO:1903532","BP","GO:1903532","positive regulation of secretion by cell","24/173","348/21081",1.2798274916426e-15,2.39558899206582e-14,9.32941718925188e-15,"CYP19A1/NR1H4/PTPN11/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/CNR1/IL6/NR1H2/SRC/TLR4/EGFR/MIF/MIF/SNCA/CD38/CFTR/IL2",24
"GO:0061045","BP","GO:0061045","negative regulation of wound healing","15/173","94/21081",1.47637441774478e-15,2.75136618464806e-14,1.07149611481754e-14,"PLG/HMGCR/ALOX5/ALOX5/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NOS3/F2",15
"GO:0051403","BP","GO:0051403","stress-activated MAPK cascade","23/173","315/21081",1.52950148781188e-15,2.83792655969985e-14,1.10520631525639e-14,"HMGCR/MAPK3/IGF1R/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MAPK8/PRMT1/IKBKB/MAPK1/CHUK/AKT1/TLR4/EGFR/XDH/MAPK10/MAPK14/APP",23
"GO:0050435","BP","GO:0050435","amyloid-beta metabolic process","13/173","60/21081",1.79335528798223e-15,3.31302896462457e-14,1.29023089826456e-14,"BACE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/ACE/APP/PSEN2/PSEN1",13
"GO:0002676","BP","GO:0002676","regulation of chronic inflammatory response","10/173","24/21081",1.89239686527295e-15,3.46585960368308e-14,1.34974948829813e-14,"CYP19A1/IDO1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",10
"GO:0031649","BP","GO:0031649","heat generation","10/173","24/21081",1.89239686527295e-15,3.46585960368308e-14,1.34974948829813e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CNR1/PTGS2",10
"GO:0090322","BP","GO:0090322","regulation of superoxide metabolic process","12/173","46/21081",1.93765769902152e-15,3.53352255928861e-14,1.37610024976817e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/EGFR/MAPT/MAPT/MAPT",12
"GO:0002793","BP","GO:0002793","positive regulation of peptide secretion","20/173","221/21081",1.99565453231908e-15,3.60686633056987e-14,1.404663356494e-14,"NR1H4/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/IL6/NR1H2/SRC/TLR4/EGFR/MIF/MIF/CD38/CFTR/IL2",20
"GO:0071450","BP","GO:0071450","cellular response to oxygen radical","11/173","34/21081",2.00334303133558e-15,3.60686633056987e-14,1.404663356494e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NQO1/NOS3/MPO",11
"GO:0071451","BP","GO:0071451","cellular response to superoxide","11/173","34/21081",2.00334303133558e-15,3.60686633056987e-14,1.404663356494e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NQO1/NOS3/MPO",11
"GO:0006919","BP","GO:0006919","activation of cysteine-type endopeptidase activity involved in apoptotic process","15/173","96/21081",2.04870542753204e-15,3.65754174856455e-14,1.42439846620096e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/XDH/SNCA/MAPT/MAPT/MAPT/VCP",15
"GO:0046889","BP","GO:0046889","positive regulation of lipid biosynthetic process","15/173","96/21081",2.04870542753204e-15,3.65754174856455e-14,1.42439846620096e-14,"NR1H4/NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTGS2/NR1H2/HTR2A/MTOR/AKT1",15
"GO:0031050","BP","GO:0031050","dsRNA processing","13/173","61/21081",2.26297847431813e-15,4.00641480724073e-14,1.56026410597724e-14,"ESR1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/IL6/EGFR/STAT3",13
"GO:0070918","BP","GO:0070918","production of small RNA involved in gene silencing by RNA","13/173","61/21081",2.26297847431813e-15,4.00641480724073e-14,1.56026410597724e-14,"ESR1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/IL6/EGFR/STAT3",13
"GO:1903428","BP","GO:1903428","positive regulation of reactive oxygen species biosynthetic process","14/173","78/21081",2.39353102264358e-15,4.21996403120854e-14,1.64342903148972e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTGS2/MTOR/AKT1/TLR4/HDAC4/INSR",14
"GO:0071375","BP","GO:0071375","cellular response to peptide hormone stimulus","24/173","359/21081",2.56824124304836e-15,4.50927976930269e-14,1.75610058028361e-14,"NR1H4/SRD5A1/PTPN11/IGF1R/MDM2/PPARG/AGTR1/PRKCB/SRC/GSK3B/CSK/PIK3CA/CDK4/CCNA2/AKT1/PARP1/INSR/PTK2/SIRT1/STAT5B/GLP1R/STAT3/ESRRA/OGT",24
"GO:1902895","BP","GO:1902895","positive regulation of pri-miRNA transcription by RNA polymerase II","12/173","47/21081",2.58364300227679e-15,4.51765395747905e-14,1.75936183650817e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SREBF2/TERT/PPARG/STAT3",12
"GO:0002941","BP","GO:0002941","synoviocyte proliferation","8/173","11/21081",2.82404773999757e-15,4.8322369667488e-14,1.88187350874611e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:1901645","BP","GO:1901645","regulation of synoviocyte proliferation","8/173","11/21081",2.82404773999757e-15,4.8322369667488e-14,1.88187350874611e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:1901671","BP","GO:1901671","positive regulation of superoxide dismutase activity","8/173","11/21081",2.82404773999757e-15,4.8322369667488e-14,1.88187350874611e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:1904833","BP","GO:1904833","positive regulation of removal of superoxide radicals","8/173","11/21081",2.82404773999757e-15,4.8322369667488e-14,1.88187350874611e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0002673","BP","GO:0002673","regulation of acute inflammatory response","13/173","62/21081",2.843161312514e-15,4.8322369667488e-14,1.88187350874611e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CNR1/PPARG/PTGS2/IL6/PIK3CG",13
"GO:0045429","BP","GO:0045429","positive regulation of nitric oxide biosynthetic process","13/173","62/21081",2.843161312514e-15,4.8322369667488e-14,1.88187350874611e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTGS2/MTOR/AKT1/TLR4/INSR",13
"GO:0051353","BP","GO:0051353","positive regulation of oxidoreductase activity","13/173","62/21081",2.843161312514e-15,4.8322369667488e-14,1.88187350874611e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/AGTR1/AKT1/SNCA/ABL1",13
"GO:0032768","BP","GO:0032768","regulation of monooxygenase activity","14/173","79/21081",2.8885532099342e-15,4.88982573267348e-14,1.90430096289225e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/CNR1/NOS3/AKT1/EGFR/SNCA",14
"GO:0032800","BP","GO:0032800","receptor biosynthetic process","11/173","35/21081",2.90095413764955e-15,4.89133100431466e-14,1.90488717810572e-14,"PPARA/NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG",11
"GO:0030730","BP","GO:0030730","sequestering of triglyceride","10/173","25/21081",3.13181927116087e-15,5.24030937576214e-14,2.04079383104336e-14,"PPARA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG",10
"GO:0002678","BP","GO:0002678","positive regulation of chronic inflammatory response","9/173","17/21081",3.14492560795327e-15,5.24030937576214e-14,2.04079383104336e-14,"IDO1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",9
"GO:1900222","BP","GO:1900222","negative regulation of amyloid-beta clearance","9/173","17/21081",3.14492560795327e-15,5.24030937576214e-14,2.04079383104336e-14,"HMGCR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",9
"GO:1904407","BP","GO:1904407","positive regulation of nitric oxide metabolic process","13/173","63/21081",3.5571116402741e-15,5.90397162481431e-14,2.29925143853243e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTGS2/MTOR/AKT1/TLR4/INSR",13
"GO:0045732","BP","GO:0045732","positive regulation of protein catabolic process","21/173","261/21081",4.08508462004383e-15,6.75390060333316e-14,2.63024903653856e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MDM2/GSK3B/CSNK2A1/AKT1/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/PTK2/VCP/PSEN1",21
"GO:0000303","BP","GO:0000303","response to superoxide","11/173","36/21081",4.14793667504216e-15,6.8048582750016e-14,2.65009406753354e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NQO1/NOS3/MPO",11
"GO:1900017","BP","GO:1900017","positive regulation of cytokine production involved in inflammatory response","11/173","36/21081",4.14793667504216e-15,6.8048582750016e-14,2.65009406753354e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/TLR4/STAT3",11
"GO:0051402","BP","GO:0051402","neuron apoptotic process","21/173","262/21081",4.41022961085528e-15,7.20733292943234e-14,2.80683439200992e-14,"G6PD/BACE1/BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/XIAP/PIK3CA/NQO1/PARP1/HDAC4/RHOA/APP/C5AR1/PSEN1",21
"GO:0009408","BP","GO:0009408","response to heat","19/173","201/21081",4.66643700274337e-15,7.57009098162516e-14,2.94810742419015e-14,"MAPK3/PTGS2/GSK3B/MTOR/MAPK1/NOS3/AKT1/NOS1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SIRT1/MAPT/MAPT/MAPT/VCP/EP300",19
"GO:2001056","BP","GO:2001056","positive regulation of cysteine-type endopeptidase activity","18/173","173/21081",4.66783675496774e-15,7.57009098162516e-14,2.94810742419015e-14,"CTSD/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/XDH/SNCA/RHOA/SIRT1/MAPT/MAPT/MAPT/VCP",18
"GO:0050999","BP","GO:0050999","regulation of nitric-oxide synthase activity","13/173","65/21081",5.50133573497139e-15,8.88789944406594e-14,3.46131670017011e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/CNR1/NOS3/AKT1/EGFR",13
"GO:1903034","BP","GO:1903034","regulation of response to wounding","19/173","203/21081",5.60376624106416e-15,9.01909195389455e-14,3.51240850516462e-14,"PLG/HMGCR/ALOX5/ALOX5/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRKCA/MTOR/NOS3/TLR4/PTK2/F2",19
"GO:0000305","BP","GO:0000305","response to oxygen radical","11/173","37/21081",5.8612369433707e-15,9.39788519712533e-14,3.65992630585054e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NQO1/NOS3/MPO",11
"GO:0051092","BP","GO:0051092","positive regulation of NF-kappaB transcription factor activity","19/173","205/21081",6.71575998658106e-15,1.07275429259334e-13,4.17775017764362e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRKCB/IKBKB/CHUK/TLR4/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/STAT3/APP",19
"GO:0009266","BP","GO:0009266","response to temperature stimulus","21/173","269/21081",7.46989089530852e-15,1.188747805774e-13,4.62947703032722e-14,"MAPK3/PPARG/PTGS2/GSK3B/HTR2A/MTOR/MAPK1/NOS3/AKT1/NOS1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SIRT1/MAPT/MAPT/MAPT/VCP/EP300",21
"GO:0048638","BP","GO:0048638","regulation of developmental growth","24/173","377/21081",7.62623976509443e-15,1.20910047618979e-13,4.7087387709067e-14,"G6PD/PPARA/SLC6A3/SLC6A3/DRD2/DRD3/GSK3B/MTOR/PIK3CA/CDK4/MAPK1/PIM1/AKT1/INSR/PTK2/STAT5B/ABL1/STAT3/MAPK14/CDK1/APP/MAPT/MAPT/MAPT",24
"GO:0071800","BP","GO:0071800","podosome assembly","10/173","27/21081",7.96959951402837e-15,1.24955086107404e-13,4.86626934785496e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SRC/RHOA",10
"GO:0150078","BP","GO:0150078","positive regulation of neuroinflammatory response","10/173","27/21081",7.96959951402837e-15,1.24955086107404e-13,4.86626934785496e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/LRRK2",10
"GO:1900409","BP","GO:1900409","positive regulation of cellular response to oxidative stress","10/173","27/21081",7.96959951402837e-15,1.24955086107404e-13,4.86626934785496e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TLR4/MMP3",10
"GO:0046136","BP","GO:0046136","positive regulation of vitamin metabolic process","8/173","12/21081",8.41318564060336e-15,1.30943684201186e-13,5.0994901974276e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0060664","BP","GO:0060664","epithelial cell proliferation involved in salivary gland morphogenesis","8/173","12/21081",8.41318564060336e-15,1.30943684201186e-13,5.0994901974276e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0045861","BP","GO:0045861","negative regulation of proteolysis","25/173","420/21081",9.36228657041042e-15,1.4518377969954e-13,5.6540585818998e-14,"FABP1/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MDM2/XIAP/PTGS2/NR1H2/SRC/CSNK2A1/CSNK2A2/AKT1/LRRK2/SNCA/F2/MMP9/APP/OGT/PSEN1",25
"GO:0045940","BP","GO:0045940","positive regulation of steroid metabolic process","11/173","39/21081",1.13285238348289e-14,1.74401803529667e-13,6.79192962179674e-14,"CES1/CES1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/AGTR1",11
"GO:0060055","BP","GO:0060055","angiogenesis involved in wound healing","11/173","39/21081",1.13285238348289e-14,1.74401803529667e-13,6.79192962179674e-14,"ALOX5/ALOX5/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",11
"GO:0010950","BP","GO:0010950","positive regulation of endopeptidase activity","19/173","211/21081",1.1424578832939e-14,1.74532835103669e-13,6.79703253478757e-14,"CTSD/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/XDH/SNCA/RHOA/SIRT1/STAT3/MAPT/MAPT/MAPT/VCP",19
"GO:0000187","BP","GO:0000187","activation of MAPK activity","18/173","182/21081",1.14409484941882e-14,1.74532835103669e-13,6.79703253478757e-14,"MAPK3/PTPN11/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MAPK1/TLR4/LRRK2/INSR/MAPK10/MAPK14/CDK1/C5AR1",18
"GO:0019722","BP","GO:0019722","calcium-mediated signaling","20/173","242/21081",1.14602638253527e-14,1.74532835103669e-13,6.79703253478757e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CXCR3/AGTR1/GSK3B/MTOR/NOS1/LRRK2/EGFR/HDAC4/CXCL8/MAPT/MAPT/MAPT",20
"GO:0010829","BP","GO:0010829","negative regulation of glucose transmembrane transport","10/173","28/21081",1.23099956561847e-14,1.86139400509355e-13,7.24904033396604e-14,"FABP5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRKCB",10
"GO:0051000","BP","GO:0051000","positive regulation of nitric-oxide synthase activity","10/173","28/21081",1.23099956561847e-14,1.86139400509355e-13,7.24904033396604e-14,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/AKT1",10
"GO:2001243","BP","GO:2001243","negative regulation of intrinsic apoptotic signaling pathway","15/173","108/21081",1.25993264411689e-14,1.89838787406123e-13,7.39310980422453e-14,"BCL2L1/MDM2/PTGS2/SRC/AKT1/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/MIF/MIF/MMP9/SIRT1",15
"GO:1901568","BP","GO:1901568","fatty acid derivative metabolic process","19/173","213/21081",1.3586612628752e-14,2.03991226358894e-13,7.94426447922562e-14,"FABP5/MAPK3/PTGS1/ALOX5/ALOX5/PTGS2/MIF/MIF/AKR1C1/CBR1/SIRT1/EPHX1/ABCC1/ABCC1/CYP1B1/FASN/MGLL/ACACA/ACACA",19
"GO:1903039","BP","GO:1903039","positive regulation of leukocyte cell-cell adhesion","22/173","313/21081",1.44522747092294e-14,2.16224349434915e-13,8.42067303295354e-14,"PTPN11/ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/SRC/CSK/PIK3CA/AKT1/RHOA/STAT5B/DPP4/IL2/ELANE/ELANE",22
"GO:1903035","BP","GO:1903035","negative regulation of response to wounding","15/173","109/21081",1.45069778165639e-14,2.16281223658176e-13,8.422887951113e-14,"PLG/HMGCR/ALOX5/ALOX5/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NOS3/F2",15
"GO:1903037","BP","GO:1903037","regulation of leukocyte cell-cell adhesion","25/173","429/21081",1.51871224676049e-14,2.25629662114871e-13,8.78695492052811e-14,"PPARA/PTPN11/ALOX5/ALOX5/IDO1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/SRC/ERBB2/CSK/PIK3CA/AKT1/RHOA/STAT5B/DPP4/IL2/ELANE/ELANE",25
"GO:0046324","BP","GO:0046324","regulation of glucose import","13/173","70/21081",1.53488031205077e-14,2.27237158393857e-13,8.84955749328372e-14,"PTPN11/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/AKT1/INSR/MAPK14",13
"GO:0010631","BP","GO:0010631","epithelial cell migration","24/173","392/21081",1.80602611320977e-14,2.66451560938483e-13,1.0376728983793e-13,"PTPN11/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/PTGS2/SRC/PRKCA/MTOR/PIK3CA/NOS3/AKT1/PTK2/MMP9/RHOA/SIRT1/ABL1/CYP1B1/DPP4",24
"GO:1903708","BP","GO:1903708","positive regulation of hemopoiesis","20/173","248/21081",1.82990838283603e-14,2.69040855317311e-13,1.04775668469067e-13,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRKCA/PRMT1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/RHOA/STAT5B/STAT3/MAPK14/IL2",20
"GO:0071674","BP","GO:0071674","mononuclear cell migration","16/173","134/21081",1.84218374973494e-14,2.69911681124957e-13,1.05114804159104e-13,"PLG/MAPK3/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/MAPK1/PTK2/MAPK14/C5AR1",16
"GO:1902884","BP","GO:1902884","positive regulation of response to oxidative stress","10/173","29/21081",1.86568458649812e-14,2.72415594777681e-13,1.06089931994033e-13,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TLR4/MMP3",10
"GO:0001558","BP","GO:0001558","regulation of cell growth","26/173","477/21081",2.07983132850855e-14,3.0264394913811e-13,1.17862107008487e-13,"G6PD/PPARA/ESR2/PPARG/AGTR1/GSK3B/ERBB2/CSNK2A1/MTOR/AKT1/EGFR/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/F2/RHOA/SIRT1/ABL1/CD38/MAPT/MAPT/MAPT/IL2/PPP2CA",26
"GO:0042635","BP","GO:0042635","positive regulation of hair cycle","9/173","20/21081",2.12752861002012e-14,3.08527954401894e-13,1.2015358271786e-13,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT",9
"GO:0090132","BP","GO:0090132","epithelium migration","24/173","395/21081",2.1360731727804e-14,3.08713432351834e-13,1.20225815524912e-13,"PTPN11/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/PTGS2/SRC/PRKCA/MTOR/PIK3CA/NOS3/AKT1/PTK2/MMP9/RHOA/SIRT1/ABL1/CYP1B1/DPP4",24
"GO:0061046","BP","GO:0061046","regulation of branching involved in lung morphogenesis","8/173","13/21081",2.17220665945278e-14,3.11814395135638e-13,1.2143345905618e-13,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:1901668","BP","GO:1901668","regulation of superoxide dismutase activity","8/173","13/21081",2.17220665945278e-14,3.11814395135638e-13,1.2143345905618e-13,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0035196","BP","GO:0035196","production of miRNAs involved in gene silencing by miRNA","12/173","56/21081",2.59058392227186e-14,3.70619228475864e-13,1.44334500294573e-13,"ESR1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/EGFR/STAT3",12
"GO:1902930","BP","GO:1902930","regulation of alcohol biosynthetic process","14/173","92/21081",2.66798098717686e-14,3.80411114581023e-13,1.48147866896575e-13,"HMGCR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SREBF2/SNCA/FASN/ACACA/ACACA",14
"GO:0010573","BP","GO:0010573","vascular endothelial growth factor production","13/173","73/21081",2.73106992604582e-14,3.88104217918685e-13,1.51143880434572e-13,"RORA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTGS2/IL6/CYP1B1/C5AR1",13
"GO:0050848","BP","GO:0050848","regulation of calcium-mediated signaling","15/173","114/21081",2.87422184561027e-14,4.07085620733268e-13,1.58536026010503e-13,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GSK3B/MTOR/NOS1/LRRK2/MAPT/MAPT/MAPT",15
"GO:0090130","BP","GO:0090130","tissue migration","24/173","401/21081",2.975035530738e-14,4.19964317943714e-13,1.63551524893168e-13,"PTPN11/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/PTGS2/SRC/PRKCA/MTOR/PIK3CA/NOS3/AKT1/PTK2/MMP9/RHOA/SIRT1/ABL1/CYP1B1/DPP4",24
"GO:0030198","BP","GO:0030198","extracellular matrix organization","25/173","442/21081",2.99258703075527e-14,4.21043122307257e-13,1.63971656059508e-13,"PLG/TTR/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/PTK2/MMP3/MMP9/CTSG/ABL1/MMP2/CYP1B1/MMP13/APP/MMP12/DPP4/ELANE/ELANE",25
"GO:0043062","BP","GO:0043062","extracellular structure organization","25/173","443/21081",3.1498233137094e-14,4.41702945872979e-13,1.72017448294292e-13,"PLG/TTR/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/PTK2/MMP3/MMP9/CTSG/ABL1/MMP2/CYP1B1/MMP13/APP/MMP12/DPP4/ELANE/ELANE",25
"GO:0008217","BP","GO:0008217","regulation of blood pressure","18/173","193/21081",3.20517185140838e-14,4.47986026205072e-13,1.74464340388295e-13,"PPARA/PTGS1/NOS2/CES1/CES1/DRD2/CNR1/PPARG/PTGS2/AGTR1/DRD3/NOS3/NOS1/ACE/RHOA/CTSG/GLP1R/CACNA1B",18
"GO:0001503","BP","GO:0001503","ossification","25/173","448/21081",4.06078169883241e-14,5.65713489781604e-13,2.20312297862452e-13,"MAPK3/PTPN11/ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTGS2/IL6/MAPK1/AKT1/EGFR/HDAC4/PTK2/RHOA/MMP2/MAPK14/ESRRA/MMP13/FASN",25
"GO:0046942","BP","GO:0046942","carboxylic acid transport","23/173","368/21081",4.27730669424939e-14,5.93930592936787e-13,2.3130120823392e-13,"NR1H4/FABP4/FABP5/SLC22A6/PPARA/FABP1/NOS2/CES1/CES1/DRD2/PPARG/DRD3/AKT1/MIF/MIF/AKR1C1/ACE/ABCC1/ABCC1/ABCG2/ACACA/ACACA/PSEN1",23
"GO:0001936","BP","GO:0001936","regulation of endothelial cell proliferation","18/173","197/21081",4.58611942215142e-14,6.34736854225452e-13,2.47192858961839e-13,"ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/AGTR1/PRKCA/MTOR/AKT1/XDH/SIRT1/STAT3",18
"GO:0001101","BP","GO:0001101","response to acid chemical","16/173","142/21081",4.65008096317335e-14,6.41499805601415e-13,2.49826632744652e-13,"BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MTOR/CHUK/EGFR/AKR1B1/RHOA/MAPK10/MMP2",16
"GO:1900034","BP","GO:1900034","regulation of cellular response to heat","14/173","96/21081",4.92584439406079e-14,6.77343457293343e-13,2.63785637454048e-13,"MAPK3/GSK3B/MTOR/MAPK1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SIRT1/MAPT/MAPT/MAPT/EP300",14
"GO:0060558","BP","GO:0060558","regulation of calcidiol 1-monooxygenase activity","8/173","14/21081",5.03321387540308e-14,6.89875024406054e-13,2.68665949478222e-13,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0015849","BP","GO:0015849","organic acid transport","23/173","371/21081",5.07881173017372e-14,6.92457868814452e-13,2.69671816223339e-13,"NR1H4/FABP4/FABP5/SLC22A6/PPARA/FABP1/NOS2/CES1/CES1/DRD2/PPARG/DRD3/AKT1/MIF/MIF/AKR1C1/ACE/ABCC1/ABCC1/ABCG2/ACACA/ACACA/PSEN1",23
"GO:0032722","BP","GO:0032722","positive regulation of chemokine production","12/173","59/21081",5.08465180207364e-14,6.92457868814452e-13,2.69671816223339e-13,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/TLR4/MIF/MIF",12
"GO:0010721","BP","GO:0010721","negative regulation of cell development","23/173","372/21081",5.37614474615835e-14,7.29815943336321e-13,2.84220599998686e-13,"G6PD/PPARA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/MDM2/IL6/DRD3/GSK3B/LRRK2/PTK2/F2/RHOA/STAT3/APP/CD38/PSEN1",23
"GO:0072521","BP","GO:0072521","purine-containing compound metabolic process","26/173","497/21081",5.42744857555005e-14,7.34434044506757e-13,2.86019080146319e-13,"PPARA/HMGCR/NOS2/TTR/RORA/PDE4A/HTR2A/NOS3/PARP1/NOS1/LRRK2/HDAC4/XDH/INSR/RHOA/STAT3/ABCG2/APP/PFKFB3/FASN/ACACA/ACACA/OGT/VCP/EP300/PSEN1",26
"GO:0051023","BP","GO:0051023","regulation of immunoglobulin secretion","10/173","32/21081",5.88311409230927e-14,7.91055436019687e-13,3.08069798571292e-13,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/IL2",10
"GO:0060252","BP","GO:0060252","positive regulation of glial cell proliferation","10/173","32/21081",5.88311409230927e-14,7.91055436019687e-13,3.08069798571292e-13,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/MTOR",10
"GO:1901550","BP","GO:1901550","regulation of endothelial cell development","9/173","22/21081",6.2128277593517e-14,8.30135382059288e-13,3.23289150536275e-13,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IKBKB",9
"GO:1903140","BP","GO:1903140","regulation of establishment of endothelial barrier","9/173","22/21081",6.2128277593517e-14,8.30135382059288e-13,3.23289150536275e-13,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IKBKB",9
"GO:0043523","BP","GO:0043523","regulation of neuron apoptotic process","19/173","232/21081",6.46531006421442e-14,8.60729409438499e-13,3.35203733791807e-13,"G6PD/BACE1/BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/PIK3CA/NQO1/PARP1/HDAC4/RHOA/C5AR1/PSEN1",19
"GO:0006690","BP","GO:0006690","icosanoid metabolic process","16/173","145/21081",6.48231139139373e-14,8.60729409438499e-13,3.35203733791807e-13,"FABP5/MAPK3/PTGS1/ALOX5/ALOX5/PTGS2/MIF/MIF/AKR1C1/CBR1/SIRT1/EPHX1/ABCC1/ABCC1/CYP1B1/MGLL",16
"GO:1900542","BP","GO:1900542","regulation of purine nucleotide metabolic process","15/173","121/21081",7.08735694913409e-14,9.38136438531799e-13,3.65349241647444e-13,"PPARA/NOS2/HTR2A/NOS3/PARP1/NOS1/HDAC4/INSR/STAT3/APP/PFKFB3/OGT/VCP/EP300/PSEN1",15
"GO:0045927","BP","GO:0045927","positive regulation of growth","21/173","302/21081",7.37440525563207e-14,9.73100867427971e-13,3.78965840531337e-13,"SLC6A3/SLC6A3/DRD2/ERBB2/CSNK2A1/MTOR/MAPK1/PIM1/AKT1/EGFR/INSR/F2/RHOA/STAT5B/MAPK14/CDK1/CD38/MAPT/MAPT/MAPT/IL2",21
"GO:0050678","BP","GO:0050678","regulation of epithelial cell proliferation","24/173","419/21081",7.77210514902098e-14,1.02240479189443e-12,3.9816683377093e-13,"ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/AGTR1/ERBB2/PRKCA/MTOR/AKT1/TLR4/EGFR/XDH/CCND1/SIRT1/STAT3/MMP12/C5AR1",24
"GO:0008630","BP","GO:0008630","intrinsic apoptotic signaling pathway in response to DNA damage","15/173","122/21081",8.02399699150339e-14,1.05228281533636e-12,4.0980257539452e-13,"BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CHEK2/MIF/MIF/SIRT1/ABL1/EP300",15
"GO:0034605","BP","GO:0034605","cellular response to heat","16/173","147/21081",8.05482281098509e-14,1.0530751422731e-12,4.10111140368212e-13,"MAPK3/PTGS2/GSK3B/MTOR/MAPK1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SIRT1/MAPT/MAPT/MAPT/VCP/EP300",16
"GO:0046427","BP","GO:0046427","positive regulation of receptor signaling pathway via JAK-STAT","14/173","100/21081",8.84192228944755e-14,1.15243336833934e-12,4.48805354827625e-13,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/AKR1B1/F2/STAT3/CYP1B1/IL2",14
"GO:0006140","BP","GO:0006140","regulation of nucleotide metabolic process","15/173","123/21081",9.07407714870717e-14,1.17548029892856e-12,4.57780785550952e-13,"PPARA/NOS2/HTR2A/NOS3/PARP1/NOS1/HDAC4/INSR/STAT3/APP/PFKFB3/OGT/VCP/EP300/PSEN1",15
"GO:0098869","BP","GO:0098869","cellular oxidant detoxification","15/173","123/21081",9.07407714870717e-14,1.17548029892856e-12,4.57780785550952e-13,"FABP1/PTGS1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTGS2/NQO1/NOS3/GSR/MPO",15
"GO:0007159","BP","GO:0007159","leukocyte cell-cell adhesion","25/173","465/21081",9.40137729527197e-14,1.21417787621917e-12,4.72851227264999e-13,"PPARA/PTPN11/ALOX5/ALOX5/IDO1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/SRC/ERBB2/CSK/PIK3CA/AKT1/RHOA/STAT5B/DPP4/IL2/ELANE/ELANE",25
"GO:0002876","BP","GO:0002876","positive regulation of chronic inflammatory response to antigenic stimulus","8/173","15/21081",1.07104126059098e-13,1.37904676250033e-12,5.37058010095384e-13,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:1904659","BP","GO:1904659","glucose transmembrane transport","15/173","125/21081",1.15657968553009e-13,1.48468491958228e-12,5.78197890174367e-13,"FABP5/PTPN11/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/PRKCB/AKT1/INSR/MAPK14",15
"GO:0002544","BP","GO:0002544","chronic inflammatory response","10/173","34/21081",1.179053120779e-13,1.50897491270782e-12,5.87657421009699e-13,"CYP19A1/IDO1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",10
"GO:1903578","BP","GO:1903578","regulation of ATP metabolic process","15/173","126/21081",1.30362700908575e-13,1.66339674522683e-12,6.47795687777082e-13,"PPARA/HTR2A/PARP1/HDAC4/INSR/SNCA/RHOA/STAT3/CDK1/APP/PFKFB3/OGT/VCP/EP300/PSEN1",15
"GO:0032642","BP","GO:0032642","regulation of chemokine production","13/173","82/21081",1.3250588054208e-13,1.68568109707575e-12,6.56474138708321e-13,"NR1H4/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/TLR4/MIF/MIF",13
"GO:1904894","BP","GO:1904894","positive regulation of receptor signaling pathway via STAT","14/173","103/21081",1.34801280522521e-13,1.70976310728415e-12,6.65852672368901e-13,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/AKR1B1/F2/STAT3/CYP1B1/IL2",14
"GO:0031960","BP","GO:0031960","response to corticosteroid","17/173","180/21081",1.38917662508088e-13,1.75672960713353e-12,6.84143375509758e-13,"SRD5A1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTGS2/IL6/SRC/PARP1/EGFR/CCND1/RHOA/MAOB",17
"GO:0060251","BP","GO:0060251","regulation of glial cell proliferation","11/173","48/21081",1.43305047084343e-13,1.80683425834235e-12,7.03656204955761e-13,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/IL6/MTOR",11
"GO:0048305","BP","GO:0048305","immunoglobulin secretion","10/173","35/21081",1.63907055254e-13,2.05460027295931e-12,8.00146568007838e-13,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/IL2",10
"GO:0001935","BP","GO:0001935","endothelial cell proliferation","18/173","212/21081",1.63923156632903e-13,2.05460027295931e-12,8.00146568007838e-13,"ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/AGTR1/PRKCA/MTOR/AKT1/XDH/SIRT1/STAT3",18
"GO:1904707","BP","GO:1904707","positive regulation of vascular associated smooth muscle cell proliferation","12/173","65/21081",1.75333530666043e-13,2.19115344647064e-12,8.53326037792632e-13,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/MDM2/MMP9/MMP2",12
"GO:0050768","BP","GO:0050768","negative regulation of neurogenesis","21/173","316/21081",1.78903009596512e-13,2.2292049494885e-12,8.68144871386685e-13,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/MDM2/IL6/DRD3/GSK3B/LRRK2/PTK2/F2/RHOA/STAT3/APP/CD38/PSEN1",21
"GO:0050808","BP","GO:0050808","synapse organization","25/173","479/21081",1.8275365681951e-13,2.27052715738625e-12,8.84237453124868e-13,"IGF1R/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/ERBB2/LRRK2/INSR/PTK2/SNCA/RHOA/ABL1/MAPK14/APP/MAPT/MAPT/MAPT/C5AR1/VCP/PSEN1",25
"GO:0008645","BP","GO:0008645","hexose transmembrane transport","15/173","129/21081",1.85500824147021e-13,2.29793878076004e-12,8.94912676259376e-13,"FABP5/PTPN11/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/PRKCB/AKT1/INSR/MAPK14",15
"GO:0002874","BP","GO:0002874","regulation of chronic inflammatory response to antigenic stimulus","8/173","16/21081",2.12717849594348e-13,2.59061036888974e-12,1.00889113225271e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0010692","BP","GO:0010692","regulation of alkaline phosphatase activity","8/173","16/21081",2.12717849594348e-13,2.59061036888974e-12,1.00889113225271e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0060556","BP","GO:0060556","regulation of vitamin D biosynthetic process","8/173","16/21081",2.12717849594348e-13,2.59061036888974e-12,1.00889113225271e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0071550","BP","GO:0071550","death-inducing signaling complex assembly","8/173","16/21081",2.12717849594348e-13,2.59061036888974e-12,1.00889113225271e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0097527","BP","GO:0097527","necroptotic signaling pathway","8/173","16/21081",2.12717849594348e-13,2.59061036888974e-12,1.00889113225271e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0042987","BP","GO:0042987","amyloid precursor protein catabolic process","12/173","66/21081",2.12784894973528e-13,2.59061036888974e-12,1.00889113225271e-12,"BACE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/APP/PSEN2/PSEN1",12
"GO:0045428","BP","GO:0045428","regulation of nitric oxide biosynthetic process","13/173","85/21081",2.14831426010602e-13,2.60805351176871e-12,1.01568421560501e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTGS2/MTOR/AKT1/TLR4/INSR",13
"GO:0009314","BP","GO:0009314","response to radiation","25/173","483/21081",2.20049898748568e-13,2.66379492815574e-12,1.03739223521592e-12,"HMGCR/BACE1/BCL2L1/MAPK8/DRD2/MDM2/PTGS2/DRD3/CHEK2/MTOR/AKT1/PARP1/EGFR/CCND1/MC1R/PPP1CA/MAPK10/SIRT1/MAPK14/NOX4/TYR/APP/ELANE/ELANE/EP300",25
"GO:0006109","BP","GO:0006109","regulation of carbohydrate metabolic process","18/173","216/21081",2.26304339205656e-13,2.73172482183191e-12,1.06384695344286e-12,"PPARA/RORA/SRC/GSK3B/HTR2A/MTOR/AKT1/HDAC4/INSR/SNCA/PPP1CA/SIRT1/STAT3/APP/PFKFB3/OGT/EP300/PSEN1",18
"GO:0015749","BP","GO:0015749","monosaccharide transmembrane transport","15/173","131/21081",2.334880829173e-13,2.8104557062765e-12,1.09450802548381e-12,"FABP5/PTPN11/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/PRKCB/AKT1/INSR/MAPK14",15
"GO:0010288","BP","GO:0010288","response to lead ion","9/173","25/21081",2.4984725683039e-13,2.99042533597838e-12,1.16459566415826e-12,"BACE1/PTGS2/CDK4/PPP1CA/APP/MAPT/MAPT/MAPT/PPP2CA",9
"GO:1900221","BP","GO:1900221","regulation of amyloid-beta clearance","9/173","25/21081",2.4984725683039e-13,2.99042533597838e-12,1.16459566415826e-12,"HMGCR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",9
"GO:0015908","BP","GO:0015908","fatty acid transport","14/173","108/21081",2.64229340882424e-13,3.15368109384669e-12,1.22817422787454e-12,"FABP4/FABP5/PPARA/FABP1/NOS2/DRD2/PPARG/DRD3/AKT1/MIF/MIF/ACE/ACACA/ACACA",14
"GO:0034219","BP","GO:0034219","carbohydrate transmembrane transport","15/173","133/21081",2.92740161437418e-13,3.48188736690825e-12,1.35599136410543e-12,"FABP5/PTPN11/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/PRKCB/AKT1/INSR/MAPK14",15
"GO:0046323","BP","GO:0046323","glucose import","13/173","87/21081",2.93366833926372e-13,3.48188736690825e-12,1.35599136410543e-12,"PTPN11/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/AKT1/INSR/MAPK14",13
"GO:0006509","BP","GO:0006509","membrane protein ectodomain proteolysis","11/173","51/21081",2.9571735634858e-13,3.50000848781369e-12,1.36304848022275e-12,"BACE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PSEN2/PSEN1",11
"GO:0032770","BP","GO:0032770","positive regulation of monooxygenase activity","10/173","37/21081",3.06646067554541e-13,3.60924969816966e-12,1.40559153869584e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/AKT1",10
"GO:0050901","BP","GO:0050901","leukocyte tethering or rolling","10/173","37/21081",3.06646067554541e-13,3.60924969816966e-12,1.40559153869584e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/ELANE/ELANE",10
"GO:0043525","BP","GO:0043525","positive regulation of neuron apoptotic process","12/173","68/21081",3.10330944215268e-13,3.64253088942175e-12,1.41855261502298e-12,"BACE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NQO1/HDAC4/RHOA",12
"GO:1904019","BP","GO:1904019","epithelial cell apoptotic process","15/173","134/21081",3.27318101429866e-13,3.83133502197107e-12,1.49208077554806e-12,"SERPINE1/BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/IL6/MTOR/PIK3CG/ABL1",15
"GO:2000010","BP","GO:2000010","positive regulation of protein localization to cell surface","9/173","26/21081",3.79443991290281e-13,4.42927889833078e-12,1.7249449228118e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/AKT1",9
"GO:0002439","BP","GO:0002439","chronic inflammatory response to antigenic stimulus","8/173","17/21081",3.99004893137807e-13,4.61954166469357e-12,1.79904113584578e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0060693","BP","GO:0060693","regulation of branching involved in salivary gland morphogenesis","8/173","17/21081",3.99004893137807e-13,4.61954166469357e-12,1.79904113584578e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0071316","BP","GO:0071316","cellular response to nicotine","8/173","17/21081",3.99004893137807e-13,4.61954166469357e-12,1.79904113584578e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0022409","BP","GO:0022409","positive regulation of cell-cell adhesion","22/173","369/21081",4.11427902630405e-13,4.75042706053422e-12,1.85001333791475e-12,"PTPN11/ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/SRC/CSK/PIK3CA/AKT1/RHOA/STAT5B/DPP4/IL2/ELANE/ELANE",22
"GO:0032602","BP","GO:0032602","chemokine production","13/173","90/21081",4.61249193526764e-13,5.31124071353719e-12,2.06841743609777e-12,"NR1H4/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/TLR4/MIF/MIF",13
"GO:1901033","BP","GO:1901033","positive regulation of response to reactive oxygen species","8/173","18/21081",7.1321216474458e-13,8.19037429189114e-12,3.18967147362299e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0006163","BP","GO:0006163","purine nucleotide metabolic process","24/173","466/21081",7.71775376931035e-13,8.83901233579506e-12,3.44227803244598e-12,"PPARA/HMGCR/NOS2/RORA/PDE4A/HTR2A/NOS3/PARP1/NOS1/LRRK2/HDAC4/XDH/INSR/RHOA/STAT3/APP/PFKFB3/FASN/ACACA/ACACA/OGT/VCP/EP300/PSEN1",24
"GO:0051961","BP","GO:0051961","negative regulation of nervous system development","21/173","341/21081",7.82291426163313e-13,8.93536631658043e-12,3.47980226918146e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/MDM2/IL6/DRD3/GSK3B/LRRK2/PTK2/F2/RHOA/STAT3/APP/CD38/PSEN1",21
"GO:0072330","BP","GO:0072330","monocarboxylic acid biosynthetic process","19/173","267/21081",8.08363728362722e-13,9.20841147939198e-12,3.58613738108142e-12,"NR1H4/FABP5/PTGS1/CES1/CES1/ALOX5/ALOX5/IDO1/NR1H3/PTGS2/NR1H2/MIF/MIF/CBR1/SIRT1/FASN/MGLL/ACACA/ACACA",19
"GO:0018958","BP","GO:0018958","phenol-containing compound metabolic process","14/173","117/21081",8.15864434551024e-13,9.26900530055429e-12,3.60973512838224e-12,"SRD5A1/SLC6A3/SLC6A3/DRD2/DRD3/HTR1A/MAOA/AKR1B1/SNCA/MC1R/CTSB/CTSB/MAOB/TYR",14
"GO:0071241","BP","GO:0071241","cellular response to inorganic substance","18/173","233/21081",8.29294991216247e-13,9.39646511380756e-12,3.65937326650369e-12,"FABP4/MAPK3/BACE1/MAPK8/PTGS2/CDK2/NQO1/MAPK1/CCNA2/CHUK/AKT1/PARP1/LRRK2/EGFR/SNCA/MMP3/MMP9/APP",18
"GO:0034763","BP","GO:0034763","negative regulation of transmembrane transport","15/173","145/21081",1.05415502642762e-12,1.19125125193909e-11,4.63922648808573e-12,"FABP5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/PRKCB/DRD3/MTOR/AKT1/MMP9",15
"GO:0050707","BP","GO:0050707","regulation of cytokine secretion","12/173","75/21081",1.05947399888199e-12,1.19408621253304e-11,4.65026700053746e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/SRC/MIF/MIF",12
"GO:1902004","BP","GO:1902004","positive regulation of amyloid-beta formation","9/173","29/21081",1.19085235389393e-12,1.33860625706225e-11,5.21308799866681e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/APP",9
"GO:0002925","BP","GO:0002925","positive regulation of humoral immune response mediated by circulating immunoglobulin","8/173","19/21081",1.22334179367895e-12,1.35364043784945e-11,5.27163733460339e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0042368","BP","GO:0042368","vitamin D biosynthetic process","8/173","19/21081",1.22334179367895e-12,1.35364043784945e-11,5.27163733460339e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0051798","BP","GO:0051798","positive regulation of hair follicle development","8/173","19/21081",1.22334179367895e-12,1.35364043784945e-11,5.27163733460339e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0090154","BP","GO:0090154","positive regulation of sphingolipid biosynthetic process","8/173","19/21081",1.22334179367895e-12,1.35364043784945e-11,5.27163733460339e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:2000121","BP","GO:2000121","regulation of removal of superoxide radicals","8/173","19/21081",1.22334179367895e-12,1.35364043784945e-11,5.27163733460339e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:2000304","BP","GO:2000304","positive regulation of ceramide biosynthetic process","8/173","19/21081",1.22334179367895e-12,1.35364043784945e-11,5.27163733460339e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0070884","BP","GO:0070884","regulation of calcineurin-NFAT signaling cascade","10/173","42/21081",1.25046724774862e-12,1.38006112615166e-11,5.37453045375486e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GSK3B/MTOR",10
"GO:0030278","BP","GO:0030278","regulation of ossification","18/173","239/21081",1.27841986510978e-12,1.40383095733911e-11,5.46710003576587e-12,"MAPK3/PTPN11/ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/MAPK1/HDAC4/PTK2/MAPK14/ESRRA",18
"GO:0045787","BP","GO:0045787","positive regulation of cell cycle","23/173","433/21081",1.27861280416624e-12,1.40383095733911e-11,5.46710003576587e-12,"PTPN11/TERT/DRD2/MDM2/DRD3/SRC/PRKCA/CDK2/PRMT1/CHEK2/CDK4/AKT1/EGFR/CCND1/INSR/MIF/MIF/RHOA/STAT5B/ABL1/CDK1/APP/EP300",23
"GO:0043542","BP","GO:0043542","endothelial cell migration","20/173","311/21081",1.28236795384596e-12,1.40432511234317e-11,5.46902448031972e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/PTGS2/PRKCA/PIK3CA/NOS3/AKT1/PTK2/RHOA/SIRT1/ABL1/CYP1B1/DPP4",20
"GO:1901224","BP","GO:1901224","positive regulation of NIK/NF-kappaB signaling","13/173","98/21081",1.42521620548061e-12,1.55674644141057e-11,6.06261635777439e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TLR4/EGFR/RHOA/APP/EP300",13
"GO:0007259","BP","GO:0007259","receptor signaling pathway via JAK-STAT","16/173","177/21081",1.47517282576372e-12,1.6030714416036e-11,6.24302512343673e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/AKR1B1/F2/STAT5B/STAT3/CYP1B1/IL2/PPP2CA",16
"GO:0055088","BP","GO:0055088","lipid homeostasis","16/173","177/21081",1.47517282576372e-12,1.6030714416036e-11,6.24302512343673e-12,"NR1H4/FABP4/NR1I3/NR1I2/CES1/CES1/RORA/NR1H3/SREBF2/PPARG/NR1H2/AKR1C1/SIRT1/ACACA/ACACA/CETP",16
"GO:0014013","BP","GO:0014013","regulation of gliogenesis","15/173","149/21081",1.57375899794748e-12,1.70584234241808e-11,6.64325763902644e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/PPARG/IL6/DRD3/MTOR/F2/CDK1",15
"GO:2001242","BP","GO:2001242","regulation of intrinsic apoptotic signaling pathway","16/173","178/21081",1.60946489247579e-12,1.74010593591085e-11,6.77669428410861e-12,"BCL2L1/MDM2/PTGS2/SRC/AKT1/PARP1/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/MIF/MIF/MMP9/SIRT1",16
"GO:0106056","BP","GO:0106056","regulation of calcineurin-mediated signaling","10/173","43/21081",1.61794407707696e-12,1.74483359987309e-11,6.79510576854122e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GSK3B/MTOR",10
"GO:0070482","BP","GO:0070482","response to oxygen levels","23/173","440/21081",1.77830981690613e-12,1.91292111697067e-11,7.44970828028365e-12,"PPARA/FABP1/NOS2/RORA/TERT/DRD2/MDM2/PPARG/PTGS2/SRC/MTOR/CDK4/CCNA2/AKT1/NOS1/RHOA/SIRT1/MMP2/NOX4/CD38/DPP4/PSEN2/EP300",23
"GO:0043200","BP","GO:0043200","response to amino acid","14/173","124/21081",1.83665989096811e-12,1.97069895876856e-11,7.67471916162112e-12,"BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MTOR/CHUK/EGFR/RHOA/MMP2",14
"GO:0071230","BP","GO:0071230","cellular response to amino acid stimulus","12/173","79/21081",2.01886339242996e-12,2.15614862367836e-11,8.39693707850113e-12,"BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MTOR/EGFR/MMP2",12
"GO:0000185","BP","GO:0000185","activation of MAPKKK activity","8/173","20/21081",2.02471946539813e-12,2.15614862367836e-11,8.39693707850113e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0030656","BP","GO:0030656","regulation of vitamin metabolic process","8/173","20/21081",2.02471946539813e-12,2.15614862367836e-11,8.39693707850113e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0043535","BP","GO:0043535","regulation of blood vessel endothelial cell migration","16/173","182/21081",2.26812754075016e-12,2.40931848016185e-11,9.38288551068223e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/PTGS2/PRKCA/NOS3/AKT1/RHOA/SIRT1/ABL1",16
"GO:0060968","BP","GO:0060968","regulation of gene silencing","15/173","153/21081",2.32159089265911e-12,2.45996002566298e-11,9.58010469421217e-12,"ESR1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/PPARG/IL6/CDK2/EGFR/STAT3",15
"GO:0002863","BP","GO:0002863","positive regulation of inflammatory response to antigenic stimulus","9/173","31/21081",2.36372553827617e-12,2.49837557515808e-11,9.72971077813602e-12,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CNR1",9
"GO:0046425","BP","GO:0046425","regulation of receptor signaling pathway via JAK-STAT","15/173","154/21081",2.5539985806516e-12,2.69278907424035e-11,1.04868375833468e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/AKR1B1/F2/STAT3/CYP1B1/IL2/PPP2CA",15
"GO:1901654","BP","GO:1901654","response to ketone","17/173","216/21081",2.73292747805972e-12,2.86765311777178e-11,1.11678306998235e-11,"SRD5A1/BCL2L1/NR1H3/PPARG/SRC/CDK4/AKT1/PARP1/EGFR/AKR1B1/CCND1/SIRT1/MAOB/CD38/CFTR/ACACA/ACACA",17
"GO:1904705","BP","GO:1904705","regulation of vascular associated smooth muscle cell proliferation","13/173","103/21081",2.74009688353811e-12,2.86765311777178e-11,1.11678306998235e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/MDM2/PPARG/MMP9/MMP2",13
"GO:1990874","BP","GO:1990874","vascular associated smooth muscle cell proliferation","13/173","103/21081",2.74009688353811e-12,2.86765311777178e-11,1.11678306998235e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/MDM2/PPARG/MMP9/MMP2",13
"GO:0015909","BP","GO:0015909","long-chain fatty acid transport","12/173","81/21081",2.74900355486053e-12,2.86990567680648e-11,1.11766030990321e-11,"FABP4/FABP5/FABP1/DRD2/PPARG/DRD3/AKT1/MIF/MIF/ACE/ACACA/ACACA",12
"GO:0010632","BP","GO:0010632","regulation of epithelial cell migration","20/173","325/21081",2.88288279282517e-12,3.00229632027308e-11,1.16921871783312e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/PTGS2/SRC/PRKCA/MTOR/NOS3/AKT1/PTK2/MMP9/RHOA/SIRT1/ABL1",20
"GO:1903573","BP","GO:1903573","negative regulation of response to endoplasmic reticulum stress","11/173","62/21081",2.91977956516786e-12,3.03328688811693e-11,1.18128773039348e-11,"ALOX5/ALOX5/BCL2L1/NR1H3/NR1H2/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",11
"GO:0043122","BP","GO:0043122","regulation of I-kappaB kinase/NF-kappaB signaling","19/173","289/21081",3.28145808660132e-12,3.40071107560219e-11,1.32437794920084e-11,"NR1H4/ESR1/RORA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRKCB/IKBKB/CHUK/AKT1/TLR4/RHOA/SIRT1/ABL1",19
"GO:0016125","BP","GO:0016125","sterol metabolic process","16/173","187/21081",3.44168768348853e-12,3.5494492638696e-11,1.38230276914767e-11,"NPC1L1/CYP19A1/G6PD/NR1H4/HMGCR/CES1/CES1/SREBF2/CYP26A1/CYP1B1/APP/CFTR/FASN/ACACA/ACACA/CETP",16
"GO:0097696","BP","GO:0097696","receptor signaling pathway via STAT","16/173","187/21081",3.44168768348853e-12,3.5494492638696e-11,1.38230276914767e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/AKR1B1/F2/STAT5B/STAT3/CYP1B1/IL2/PPP2CA",16
"GO:0014009","BP","GO:0014009","glial cell proliferation","11/173","63/21081",3.51250289620858e-12,3.60498183719571e-11,1.40392945660816e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/IL6/MTOR",11
"GO:0045599","BP","GO:0045599","negative regulation of fat cell differentiation","11/173","63/21081",3.51250289620858e-12,3.60498183719571e-11,1.40392945660816e-11,"RORA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/SIRT1",11
"GO:0010951","BP","GO:0010951","negative regulation of endopeptidase activity","19/173","292/21081",3.93454070564886e-12,4.02840083332578e-11,1.56882637648193e-11,"FABP1/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MDM2/XIAP/PTGS2/SRC/CSNK2A1/AKT1/SNCA/MMP9/APP",19
"GO:0043243","BP","GO:0043243","positive regulation of protein-containing complex disassembly","10/173","47/21081",4.24796008854281e-12,4.32992323468508e-11,1.68625170626524e-11,"IGF1R/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/INSR",10
"GO:0010821","BP","GO:0010821","regulation of mitochondrion organization","17/173","222/21081",4.24941866054055e-12,4.32992323468508e-11,1.68625170626524e-11,"BCL2L1/SREBF2/MAPK8/GSK3B/CSNK2A2/AKT1/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/MMP9/MAPT/MAPT/MAPT/EP300",17
"GO:0030316","BP","GO:0030316","osteoclast differentiation","14/173","132/21081",4.36879367959355e-12,4.44091013028541e-11,1.72947460698088e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SRC/MTOR/TLR4/MAPK14/ESRRA/GLO1",14
"GO:2000810","BP","GO:2000810","regulation of bicellular tight junction assembly","9/173","33/21081",4.45882482708588e-12,4.52161018861287e-11,1.76090255701018e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IKBKB",9
"GO:0042362","BP","GO:0042362","fat-soluble vitamin biosynthetic process","8/173","22/21081",5.06841840090467e-12,5.12754994891523e-11,1.99688063313838e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0034205","BP","GO:0034205","amyloid-beta formation","10/173","48/21081",5.32813246787395e-12,5.37749046460722e-11,2.0942178371041e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/APP/PSEN1",10
"GO:0060147","BP","GO:0060147","regulation of posttranscriptional gene silencing","14/173","134/21081",5.37578070433322e-12,5.39992723704772e-11,2.10295564693588e-11,"ESR1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/PPARG/IL6/EGFR/STAT3",14
"GO:0060966","BP","GO:0060966","regulation of gene silencing by RNA","14/173","134/21081",5.37578070433322e-12,5.39992723704772e-11,2.10295564693588e-11,"ESR1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/PPARG/IL6/EGFR/STAT3",14
"GO:0043393","BP","GO:0043393","regulation of protein binding","17/173","226/21081",5.66081207476526e-12,5.67282794945226e-11,2.20923450385576e-11,"PPARA/MAPK3/TERT/MAPK8/SRC/GSK3B/AKT1/LRRK2/HDAC4/ACE/PPP1CA/MMP9/ABL1/APP/PPP2CA/EP300/PSEN1",17
"GO:0032731","BP","GO:0032731","positive regulation of interleukin-1 beta production","12/173","86/21081",5.73652555453133e-12,5.72171292986e-11,2.22827234290172e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/TLR4/STAT3/APP",12
"GO:0071229","BP","GO:0071229","cellular response to acid chemical","12/173","86/21081",5.73652555453133e-12,5.72171292986e-11,2.22827234290172e-11,"BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MTOR/EGFR/MMP2",12
"GO:0051384","BP","GO:0051384","response to glucocorticoid","15/173","163/21081",5.84796653236238e-12,5.80560976542237e-11,2.26094525058378e-11,"SRD5A1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTGS2/IL6/EGFR/CCND1/RHOA/MAOB",15
"GO:1904892","BP","GO:1904892","regulation of receptor signaling pathway via STAT","15/173","163/21081",5.84796653236238e-12,5.80560976542237e-11,2.26094525058378e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/AKR1B1/F2/STAT3/CYP1B1/IL2/PPP2CA",15
"GO:0009651","BP","GO:0009651","response to salt stress","9/173","34/21081",6.02155585248876e-12,5.95788088615586e-11,2.32024594097361e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/AKR1B1",9
"GO:0032872","BP","GO:0032872","regulation of stress-activated MAPK cascade","18/173","262/21081",6.02939228300075e-12,5.95788088615586e-11,2.32024594097361e-11,"HMGCR/MAPK3/IGF1R/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRMT1/MAPK1/AKT1/TLR4/EGFR/XDH/APP",18
"GO:0045727","BP","GO:0045727","positive regulation of translation","15/173","164/21081",6.39132778288131e-12,6.30087047551338e-11,2.45382031375978e-11,"MAPK3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/ERBB2/MTOR/CDK4/MAPK1/RHOA",15
"GO:1904035","BP","GO:1904035","regulation of epithelial cell apoptotic process","13/173","110/21081",6.45933322910935e-12,6.35317289131612e-11,2.47418904389861e-11,"SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/IL6/MTOR/ABL1",13
"GO:0045981","BP","GO:0045981","positive regulation of nucleotide metabolic process","10/173","49/21081",6.64727257702941e-12,6.50789428105944e-11,2.53444397067432e-11,"NOS2/HTR2A/NOS3/NOS1/INSR/STAT3/APP/PFKFB3/VCP/PSEN1",10
"GO:1900544","BP","GO:1900544","positive regulation of purine nucleotide metabolic process","10/173","49/21081",6.64727257702941e-12,6.50789428105944e-11,2.53444397067432e-11,"NOS2/HTR2A/NOS3/NOS1/INSR/STAT3/APP/PFKFB3/VCP/PSEN1",10
"GO:0042632","BP","GO:0042632","cholesterol homeostasis","13/173","111/21081",7.26455931814527e-12,7.09588794087339e-11,2.76343309089519e-11,"NR1H4/FABP4/NR1I3/NR1I2/CES1/CES1/RORA/NR1H3/SREBF2/NR1H2/AKR1C1/SIRT1/CETP",13
"GO:0070302","BP","GO:0070302","regulation of stress-activated protein kinase signaling cascade","18/173","265/21081",7.29646832241286e-12,7.11070961053491e-11,2.76920526384187e-11,"HMGCR/MAPK3/IGF1R/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRMT1/MAPK1/AKT1/TLR4/EGFR/XDH/APP",18
"GO:0046034","BP","GO:0046034","ATP metabolic process","20/173","342/21081",7.31326045560434e-12,7.11076514321804e-11,2.76922689057209e-11,"PPARA/HTR2A/PARP1/HDAC4/INSR/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SNCA/RHOA/STAT3/CDK1/APP/PFKFB3/OGT/VCP/EP300/PSEN1",20
"GO:0043112","BP","GO:0043112","receptor metabolic process","17/173","230/21081",7.49785719528724e-12,7.27360621524554e-11,2.83264395842142e-11,"PPARA/NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/PPARG/DRD3/INSR/SNCA/CXCL8/PSEN1",17
"GO:0042982","BP","GO:0042982","amyloid precursor protein metabolic process","12/173","88/21081",7.59674291660497e-12,7.33603651196693e-11,2.85695690547919e-11,"BACE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/APP/PSEN2/PSEN1",12
"GO:0050663","BP","GO:0050663","cytokine secretion","12/173","88/21081",7.59674291660497e-12,7.33603651196693e-11,2.85695690547919e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/SRC/MIF/MIF",12
"GO:0034250","BP","GO:0034250","positive regulation of cellular amide metabolic process","16/173","197/21081",7.63927446783023e-12,7.36038032059199e-11,2.86643739430221e-11,"MAPK3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/ERBB2/MTOR/CDK4/MAPK1/RHOA/APP",16
"GO:0046325","BP","GO:0046325","negative regulation of glucose import","8/173","23/21081",7.71751983557774e-12,7.36893073738648e-11,2.86976728126037e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0051044","BP","GO:0051044","positive regulation of membrane protein ectodomain proteolysis","8/173","23/21081",7.71751983557774e-12,7.36893073738648e-11,2.86976728126037e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0070886","BP","GO:0070886","positive regulation of calcineurin-NFAT signaling cascade","8/173","23/21081",7.71751983557774e-12,7.36893073738648e-11,2.86976728126037e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0106058","BP","GO:0106058","positive regulation of calcineurin-mediated signaling","8/173","23/21081",7.71751983557774e-12,7.36893073738648e-11,2.86976728126037e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:1902932","BP","GO:1902932","positive regulation of alcohol biosynthetic process","9/173","35/21081",8.04920351307004e-12,7.66840038722749e-11,2.98639318445742e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SNCA",9
"GO:0055092","BP","GO:0055092","sterol homeostasis","13/173","112/21081",8.16050002965946e-12,7.7570390662244e-11,3.02091276265741e-11,"NR1H4/FABP4/NR1I3/NR1I2/CES1/CES1/RORA/NR1H3/SREBF2/NR1H2/AKR1C1/SIRT1/CETP",13
"GO:0009416","BP","GO:0009416","response to light stimulus","20/173","345/21081",8.57086813032599e-12,8.12893274235605e-11,3.16574358573131e-11,"HMGCR/MAPK8/DRD2/MDM2/PTGS2/DRD3/MTOR/AKT1/PARP1/EGFR/CCND1/MC1R/PPP1CA/MAPK10/SIRT1/TYR/APP/ELANE/ELANE/EP300",20
"GO:0033559","BP","GO:0033559","unsaturated fatty acid metabolic process","14/173","139/21081",8.89560757607459e-12,8.41813732533206e-11,3.27837184611165e-11,"FABP5/MAPK3/PTGS1/ALOX5/ALOX5/PTGS2/MIF/MIF/AKR1C1/CBR1/SIRT1/EPHX1/CYP1B1/MGLL",14
"GO:0010466","BP","GO:0010466","negative regulation of peptidase activity","19/173","306/21081",8.9284795161158e-12,8.43046876977246e-11,3.28317422206644e-11,"FABP1/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MDM2/XIAP/PTGS2/SRC/CSNK2A1/AKT1/SNCA/MMP9/APP",19
"GO:0071868","BP","GO:0071868","cellular response to monoamine stimulus","13/173","113/21081",9.15629696312353e-12,8.60732429121944e-11,3.35204909781793e-11,"SRD5A1/MAPK3/DRD2/DRD3/GSK3B/HTR1A/HTR2A/MAPK1/HTR4/LRRK2/SNCA/ABL1/APP",13
"GO:0071870","BP","GO:0071870","cellular response to catecholamine stimulus","13/173","113/21081",9.15629696312353e-12,8.60732429121944e-11,3.35204909781793e-11,"SRD5A1/MAPK3/DRD2/DRD3/GSK3B/HTR1A/HTR2A/MAPK1/HTR4/LRRK2/SNCA/ABL1/APP",13
"GO:0008643","BP","GO:0008643","carbohydrate transport","15/173","169/21081",9.8767531391909e-12,9.26408920274219e-11,3.6078205959819e-11,"FABP5/PTPN11/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/PRKCB/AKT1/INSR/MAPK14",15
"GO:0042634","BP","GO:0042634","regulation of hair cycle","9/173","36/21081",1.06571537273961e-11,9.97406303693963e-11,3.88431385566117e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT",9
"GO:0001937","BP","GO:0001937","negative regulation of endothelial cell proliferation","12/173","91/21081",1.142526019297e-11,1.06694352878966e-10,4.15512065317499e-11,"ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/XDH",12
"GO:0033173","BP","GO:0033173","calcineurin-NFAT signaling cascade","10/173","52/21081",1.25286770149639e-11,1.16741992624082e-10,4.54641742094257e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GSK3B/MTOR",10
"GO:0010823","BP","GO:0010823","negative regulation of mitochondrion organization","11/173","71/21081",1.38023501196445e-11,1.28048440302117e-10,4.98673739096326e-11,"BCL2L1/AKT1/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/MAPT/MAPT/MAPT",11
"GO:0060688","BP","GO:0060688","regulation of morphogenesis of a branching structure","11/173","71/21081",1.38023501196445e-11,1.28048440302117e-10,4.98673739096326e-11,"ESR1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/LRRK2/ABL1",11
"GO:0050806","BP","GO:0050806","positive regulation of synaptic transmission","16/173","205/21081",1.39959060422382e-11,1.2956123044329e-10,5.04565171388565e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/CNR1/PTGS2/GSK3B/MAPK1/EGFR/ABL1/APP",16
"GO:0071867","BP","GO:0071867","response to monoamine","13/173","117/21081",1.43506904709426e-11,1.32269162279902e-10,5.1511098116958e-11,"SRD5A1/MAPK3/DRD2/DRD3/GSK3B/HTR1A/HTR2A/MAPK1/HTR4/LRRK2/SNCA/ABL1/APP",13
"GO:0071869","BP","GO:0071869","response to catecholamine","13/173","117/21081",1.43506904709426e-11,1.32269162279902e-10,5.1511098116958e-11,"SRD5A1/MAPK3/DRD2/DRD3/GSK3B/HTR1A/HTR2A/MAPK1/HTR4/LRRK2/SNCA/ABL1/APP",13
"GO:0006775","BP","GO:0006775","fat-soluble vitamin metabolic process","10/173","53/21081",1.53338020979207e-11,1.41024513233907e-10,5.4920794937187e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CYP26A1/CBR1",10
"GO:0032368","BP","GO:0032368","regulation of lipid transport","14/173","145/21081",1.58577978884537e-11,1.45528689477407e-10,5.66749079928366e-11,"CYP19A1/PTPN11/CES1/CES1/NR1H3/SREBF2/PPARG/AGTR1/NR1H2/AKT1/MIF/MIF/SIRT1/CETP",14
"GO:1905331","BP","GO:1905331","negative regulation of morphogenesis of an epithelium","8/173","25/21081",1.67879614434212e-11,1.53402254135691e-10,5.97412006543476e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:2000303","BP","GO:2000303","regulation of ceramide biosynthetic process","8/173","25/21081",1.67879614434212e-11,1.53402254135691e-10,5.97412006543476e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0006970","BP","GO:0006970","response to osmotic stress","12/173","94/21081",1.69298496304351e-11,1.54366804892101e-10,6.01168367270025e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTGS2/EGFR/AKR1B1/MAPK10",12
"GO:0032635","BP","GO:0032635","interleukin-6 production","16/173","208/21081",1.74425577528897e-11,1.58701130389782e-10,6.18048028570779e-11,"NR1H4/PTPN11/NOS2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/CSK/TLR4/STAT3/APP",16
"GO:0001666","BP","GO:0001666","response to hypoxia","21/173","402/21081",1.7839548627911e-11,1.61966329316226e-10,6.3076406754557e-11,"PPARA/FABP1/NOS2/RORA/TERT/DRD2/MDM2/PTGS2/SRC/MTOR/CCNA2/AKT1/NOS1/RHOA/SIRT1/MMP2/NOX4/CD38/DPP4/PSEN2/EP300",21
"GO:0043534","BP","GO:0043534","blood vessel endothelial cell migration","16/173","209/21081",1.87556101481721e-11,1.69920229252843e-10,6.61739853056371e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/PTGS2/PRKCA/NOS3/AKT1/RHOA/SIRT1/ABL1",16
"GO:0033619","BP","GO:0033619","membrane protein proteolysis","11/173","73/21081",1.89123822565972e-11,1.70975983421876e-10,6.65851397701474e-11,"BACE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PSEN2/PSEN1",11
"GO:0032755","BP","GO:0032755","positive regulation of interleukin-6 production","13/173","120/21081",1.98782345716052e-11,1.79326154341296e-10,6.98370426786533e-11,"PTPN11/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/TLR4/STAT3/APP",13
"GO:0032732","BP","GO:0032732","positive regulation of interleukin-1 production","12/173","96/21081",2.18344409727496e-11,1.96556228163587e-10,7.65471481025032e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/TLR4/STAT3/APP",12
"GO:0032715","BP","GO:0032715","negative regulation of interleukin-6 production","11/173","74/21081",2.20580508253284e-11,1.98149382572559e-10,7.71675885109963e-11,"NR1H4/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CSK/TLR4",11
"GO:0061028","BP","GO:0061028","establishment of endothelial barrier","10/173","55/21081",2.26785736559461e-11,2.03293796337796e-10,7.91710366136961e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IKBKB/FASN",10
"GO:0045948","BP","GO:0045948","positive regulation of translational initiation","9/173","39/21081",2.34889277739031e-11,2.09673222922929e-10,8.16554499349308e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MTOR",9
"GO:1902993","BP","GO:1902993","positive regulation of amyloid precursor protein catabolic process","9/173","39/21081",2.34889277739031e-11,2.09673222922929e-10,8.16554499349308e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/APP",9
"GO:0002923","BP","GO:0002923","regulation of humoral immune response mediated by circulating immunoglobulin","8/173","26/21081",2.40806358665904e-11,2.1360881377274e-10,8.31881322542139e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0090153","BP","GO:0090153","regulation of sphingolipid biosynthetic process","8/173","26/21081",2.40806358665904e-11,2.1360881377274e-10,8.31881322542139e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:1905038","BP","GO:1905038","regulation of membrane lipid metabolic process","8/173","26/21081",2.40806358665904e-11,2.1360881377274e-10,8.31881322542139e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0042509","BP","GO:0042509","regulation of tyrosine phosphorylation of STAT protein","12/173","97/21081",2.47411939223415e-11,2.19011110366727e-10,8.52920106270194e-11,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/STAT3/IL2/PPP2CA",12
"GO:0009612","BP","GO:0009612","response to mechanical stimulus","16/173","214/21081",2.68038925683034e-11,2.36777005244743e-10,9.22107869950169e-11,"MAPK3/PTPN11/BACE1/MAPK8/DRD2/PPARG/PTGS2/SRC/HTR2A/AKT1/TLR4/EGFR/HDAC4/RHOA/MPO/MAPK14",16
"GO:0048608","BP","GO:0048608","reproductive structure development","22/173","457/21081",2.79204574075538e-11,2.46128679511818e-10,9.58527168479462e-11,"CYP19A1/PLG/SRD5A1/MAPK3/PTPN11/ESR1/BCL2L1/PPARG/PTGS2/SRC/MAPK1/NOS3/AKT1/EGFR/CCND1/INSR/PTK2/CTSB/CTSB/SIRT1/STAT5B/MAPK14",22
"GO:0019058","BP","GO:0019058","viral life cycle","21/173","413/21081",2.95419997726297e-11,2.59883969014293e-10,1.01209597128852e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/HTR2A/EGFR/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/CTSB/CTSB/CXCL8/CDK1/DPP4/VCP",21
"GO:0036293","BP","GO:0036293","response to decreased oxygen levels","21/173","415/21081",3.2324033960613e-11,2.83770289873232e-10,1.10511921239851e-10,"PPARA/FABP1/NOS2/RORA/TERT/DRD2/MDM2/PTGS2/SRC/MTOR/CCNA2/AKT1/NOS1/RHOA/SIRT1/MMP2/NOX4/CD38/DPP4/PSEN2/EP300",21
"GO:0048872","BP","GO:0048872","homeostasis of number of cells","18/173","290/21081",3.26586135220366e-11,2.86116389392028e-10,1.11425589705136e-10,"G6PD/PTPN11/IL6/PRMT1/NOS3/AKT1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/MIF/MIF/STAT5B/ABL1/STAT3/MAPK14/IL2",18
"GO:0010675","BP","GO:0010675","regulation of cellular carbohydrate metabolic process","14/173","153/21081",3.29117046933277e-11,2.870873833418e-10,1.11803735024541e-10,"PPARA/RORA/SRC/GSK3B/MTOR/AKT1/HDAC4/INSR/SNCA/PPP1CA/SIRT1/STAT3/OGT/EP300",14
"GO:0097720","BP","GO:0097720","calcineurin-mediated signaling","10/173","57/21081",3.30139723142138e-11,2.870873833418e-10,1.11803735024541e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GSK3B/MTOR",10
"GO:0007249","BP","GO:0007249","I-kappaB kinase/NF-kappaB signaling","19/173","330/21081",3.30360635505851e-11,2.870873833418e-10,1.11803735024541e-10,"NR1H4/ESR1/RORA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRKCB/IKBKB/CHUK/AKT1/TLR4/RHOA/SIRT1/ABL1",19
"GO:0061458","BP","GO:0061458","reproductive system development","22/173","461/21081",3.30397106270041e-11,2.870873833418e-10,1.11803735024541e-10,"CYP19A1/PLG/SRD5A1/MAPK3/PTPN11/ESR1/BCL2L1/PPARG/PTGS2/SRC/MAPK1/NOS3/AKT1/EGFR/CCND1/INSR/PTK2/CTSB/CTSB/SIRT1/STAT5B/MAPK14",22
"GO:0042445","BP","GO:0042445","hormone metabolic process","17/173","253/21081",3.40906762674034e-11,2.95614864204483e-10,1.15124689779502e-10,"CYP19A1/AKR1B10/SRD5A1/PTPN11/ESR1/CES1/CES1/TTR/CYP26A1/AKR1B1/AKR1C1/ACE/CTSB/CTSB/CTSG/STAT5B/CYP1B1",17
"GO:0007260","BP","GO:0007260","tyrosine phosphorylation of STAT protein","12/173","100/21081",3.56910142402743e-11,3.0886175052327e-10,1.20283576772883e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/STAT3/IL2/PPP2CA",12
"GO:0070841","BP","GO:0070841","inclusion body assembly","9/173","41/21081",3.82908832471511e-11,3.30686916498263e-10,1.2878320167848e-10,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/MAPT/MAPT/MAPT/VCP",9
"GO:2000058","BP","GO:2000058","regulation of ubiquitin-dependent protein catabolic process","15/173","186/21081",3.91634952017851e-11,3.37536898808083e-10,1.31450868916849e-10,"MDM2/GSK3B/CSNK2A1/CSNK2A2/AKT1/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/PTK2/OGT/VCP/PSEN1",15
"GO:2000351","BP","GO:2000351","regulation of endothelial cell apoptotic process","11/173","78/21081",3.99056546664618e-11,3.43237098538049e-10,1.33670763127377e-10,"SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/ABL1",11
"GO:0009110","BP","GO:0009110","vitamin biosynthetic process","8/173","28/21081",4.72438049025622e-11,4.03901261631764e-10,1.5729590449397e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0010893","BP","GO:0010893","positive regulation of steroid biosynthetic process","8/173","28/21081",4.72438049025622e-11,4.03901261631764e-10,1.5729590449397e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0051797","BP","GO:0051797","regulation of hair follicle development","8/173","28/21081",4.72438049025622e-11,4.03901261631764e-10,1.5729590449397e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0035272","BP","GO:0035272","exocrine system development","10/173","59/21081",4.73604210540304e-11,4.04085198912802e-10,1.57367537300646e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/EGFR/INSR",10
"GO:1902003","BP","GO:1902003","regulation of amyloid-beta formation","9/173","42/21081",4.83928148833515e-11,4.12066273425572e-10,1.60475698758841e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/APP",9
"GO:0006633","BP","GO:0006633","fatty acid biosynthetic process","15/173","189/21081",4.9204178474093e-11,4.18137108672842e-10,1.62839933813209e-10,"FABP5/PTGS1/ALOX5/ALOX5/NR1H3/PTGS2/NR1H2/MIF/MIF/CBR1/SIRT1/FASN/MGLL/ACACA/ACACA",15
"GO:0045471","BP","GO:0045471","response to ethanol","13/173","129/21081",5.01338774524348e-11,4.25187315958873e-10,1.65585576962344e-10,"G6PD/HMGCR/SLC6A3/SLC6A3/DRD2/CNR1/NQO1/CCND1/RHOA/MAOB/STAT3/CDK1/IL2",13
"GO:0010594","BP","GO:0010594","regulation of endothelial cell migration","17/173","260/21081",5.23909213584526e-11,4.43444272613675e-10,1.72695593154723e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/PTGS2/PRKCA/NOS3/AKT1/PTK2/RHOA/SIRT1/ABL1",17
"GO:0060964","BP","GO:0060964","regulation of gene silencing by miRNA","13/173","130/21081",5.53112202881674e-11,4.6723136183782e-10,1.81959272351155e-10,"ESR1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/IL6/EGFR/STAT3",13
"GO:0001505","BP","GO:0001505","regulation of neurotransmitter levels","17/173","261/21081",5.56471258320659e-11,4.69136185834222e-10,1.82701089824577e-10,"SLC6A3/SLC6A3/BACE1/DRD2/CNR1/PRKCB/DRD3/GSK3B/HTR2A/CHRNA3/MAOA/NOS1/LRRK2/SNCA/MAOB/CACNA1B/PSEN1",17
"GO:0060425","BP","GO:0060425","lung morphogenesis","10/173","60/21081",5.64331678931917e-11,4.74820852234003e-10,1.84914934712032e-10,"MAPK3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MAPK1",10
"GO:0008625","BP","GO:0008625","extrinsic apoptotic signaling pathway via death domain receptors","12/173","104/21081",5.70942645552773e-11,4.79433853943426e-10,1.86711428918028e-10,"SERPINE1/BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GSK3B/NOS3",12
"GO:0007435","BP","GO:0007435","salivary gland morphogenesis","9/173","43/21081",6.07743983320712e-11,5.07325570496134e-10,1.97573620249947e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/EGFR",9
"GO:0045648","BP","GO:0045648","positive regulation of erythrocyte differentiation","9/173","43/21081",6.07743983320712e-11,5.07325570496134e-10,1.97573620249947e-10,"PRMT1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/STAT5B/STAT3/MAPK14",9
"GO:1902115","BP","GO:1902115","regulation of organelle assembly","16/173","226/21081",6.08223225549362e-11,5.07325570496134e-10,1.97573620249947e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SRC/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/RHOA",16
"GO:0042531","BP","GO:0042531","positive regulation of tyrosine phosphorylation of STAT protein","11/173","81/21081",6.08933963174931e-11,5.07325570496134e-10,1.97573620249947e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/STAT3/IL2",11
"GO:0050807","BP","GO:0050807","regulation of synapse organization","17/173","263/21081",6.27293023577563e-11,5.21598445632303e-10,2.03132069845284e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/LRRK2/PTK2/SNCA/RHOA/ABL1/MAPK14/APP/VCP",17
"GO:0070424","BP","GO:0070424","regulation of nucleotide-binding oligomerization domain containing signaling pathway","7/173","18/21081",6.54412867083872e-11,5.43085990671752e-10,2.11500211154574e-10,"XIAP/TLR4/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",7
"GO:0045601","BP","GO:0045601","regulation of endothelial cell differentiation","10/173","61/21081",6.70242212975595e-11,5.55138238388558e-10,2.16193856324538e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IKBKB/XDH",10
"GO:0032868","BP","GO:0032868","response to insulin","18/173","303/21081",6.71861111930649e-11,5.55396471710764e-10,2.16294423091333e-10,"NR1H4/PPARA/SRD5A1/PTPN11/IGF1R/PPARG/PRKCB/SRC/GSK3B/MTOR/PIK3CA/CDK4/AKT1/PARP1/INSR/SIRT1/ESRRA/OGT",18
"GO:0033209","BP","GO:0033209","tumor necrosis factor-mediated signaling pathway","16/173","228/21081",6.93853348383389e-11,5.72462694617674e-10,2.22940718172445e-10,"NR1H4/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IKBKB/CHUK/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",16
"GO:0030856","BP","GO:0030856","regulation of epithelial cell differentiation","15/173","194/21081",7.13329052670681e-11,5.87390531937543e-10,2.28754237208958e-10,"SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GSK3B/IKBKB/XDH/CCND1/MMP9/STAT5B",15
"GO:0045833","BP","GO:0045833","negative regulation of lipid metabolic process","12/173","106/21081",7.16685304454232e-11,5.89012738612385e-10,2.29385991774825e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CNR1/PIK3CG/AKT1/SIRT1",12
"GO:0071677","BP","GO:0071677","positive regulation of mononuclear cell migration","9/173","44/21081",7.58674767548838e-11,6.2231835662452e-10,2.42356580895504e-10,"SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",9
"GO:1901888","BP","GO:1901888","regulation of cell junction assembly","16/173","230/21081",7.90496113401605e-11,6.47171095538231e-10,2.52035268282593e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SRC/IKBKB/PTK2/SNCA/ACE/RHOA/ABL1/APP",16
"GO:0071214","BP","GO:0071214","cellular response to abiotic stimulus","19/173","348/21081",8.21057177254798e-11,6.6961073822565e-10,2.60774195907575e-10,"MAPK3/PTPN11/BCL2L1/MAPK8/MDM2/PTGS2/CHEK2/AKT1/PARP1/TLR4/EGFR/HDAC4/AKR1B1/MC1R/MAPK10/SIRT1/MAPK14/NOX4/EP300",19
"GO:0104004","BP","GO:0104004","cellular response to environmental stimulus","19/173","348/21081",8.21057177254798e-11,6.6961073822565e-10,2.60774195907575e-10,"MAPK3/PTPN11/BCL2L1/MAPK8/MDM2/PTGS2/CHEK2/AKT1/PARP1/TLR4/EGFR/HDAC4/AKR1B1/MC1R/MAPK10/SIRT1/MAPK14/NOX4/EP300",19
"GO:0006874","BP","GO:0006874","cellular calcium ion homeostasis","22/173","484/21081",8.41749299645552e-11,6.83923162675178e-10,2.6634804764598e-10,"ESR1/DRD2/CNR1/CXCR3/AGTR1/PRKCB/DRD3/TACR1/HTR2A/PIK3CG/NOS1/SNCA/F2/GLP1R/ABL1/APP/CD38/IL2/C5AR1/ELANE/ELANE/PSEN1",22
"GO:0040013","BP","GO:0040013","negative regulation of locomotion","21/173","437/21081",8.41825874509575e-11,6.83923162675178e-10,2.6634804764598e-10,"CYP19A1/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/PPARG/AKT1/MIF/MIF/RHOA/STAT3/CYP1B1/DPP4/ELANE/ELANE",21
"GO:0042359","BP","GO:0042359","vitamin D metabolic process","8/173","30/21081",8.77326881147256e-11,7.11404946182193e-10,2.77050594046502e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0032675","BP","GO:0032675","regulation of interleukin-6 production","15/173","197/21081",8.86760883019229e-11,7.17685141323563e-10,2.79496362527565e-10,"NR1H4/PTPN11/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/CSK/TLR4/STAT3/APP",15
"GO:1905897","BP","GO:1905897","regulation of response to endoplasmic reticulum stress","12/173","108/21081",8.95350085745289e-11,7.23259033142915e-10,2.81667067198638e-10,"ALOX5/ALOX5/BCL2L1/NR1H3/NR1H2/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SIRT1",12
"GO:0071496","BP","GO:0071496","cellular response to external stimulus","19/173","350/21081",9.05355884296362e-11,7.29953918856782e-10,2.8427433338937e-10,"NR1H4/PPARA/SRD5A1/MAPK3/PTPN11/SREBF2/MAPK8/MDM2/PPARG/PTGS2/MTOR/MAPK1/PIM1/AKT1/TLR4/LRRK2/EGFR/HDAC4/SIRT1",19
"GO:0072577","BP","GO:0072577","endothelial cell apoptotic process","11/173","84/21081",9.13308916415968e-11,7.34971512471865e-10,2.86228392465292e-10,"SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/ABL1",11
"GO:0031113","BP","GO:0031113","regulation of microtubule polymerization","10/173","63/21081",9.36613373571061e-11,7.52300609509156e-10,2.92977061636396e-10,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SNCA/ABL1/MAPT/MAPT/MAPT",10
"GO:0010885","BP","GO:0010885","regulation of cholesterol storage","7/173","19/21081",1.02901754575301e-10,8.24961424887647e-10,3.21274197005706e-10,"PPARA/CES1/CES1/NR1H3/SREBF2/PPARG/NR1H2",7
"GO:0003018","BP","GO:0003018","vascular process in circulatory system","15/173","200/21081",1.09823678738924e-10,8.78796254165139e-10,3.42239712513805e-10,"FABP5/HMGCR/PTGS2/AGTR1/SRC/HTR1A/HTR2A/NOS3/AKT1/NOS1/EGFR/ACE/RHOA/ABCG2/CD38",15
"GO:0042593","BP","GO:0042593","glucose homeostasis","17/173","273/21081",1.12440861494309e-10,8.98047406934813e-10,3.49736909911069e-10,"NR1H4/FABP5/HMGCR/PTPN11/ALOX5/ALOX5/IGF1R/CNR1/PPARG/IL6/PIK3CA/AKT1/INSR/SIRT1/STAT3/NOX4/CFTR",17
"GO:0051043","BP","GO:0051043","regulation of membrane protein ectodomain proteolysis","8/173","31/21081",1.1742624031523e-10,9.34352238013878e-10,3.63875517002841e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0060445","BP","GO:0060445","branching involved in salivary gland morphogenesis","8/173","31/21081",1.1742624031523e-10,9.34352238013878e-10,3.63875517002841e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0033500","BP","GO:0033500","carbohydrate homeostasis","17/173","274/21081",1.19035606992621e-10,9.45387465629242e-10,3.68173092360845e-10,"NR1H4/FABP5/HMGCR/PTPN11/ALOX5/ALOX5/IGF1R/CNR1/PPARG/IL6/PIK3CA/AKT1/INSR/SIRT1/STAT3/NOX4/CFTR",17
"GO:0010887","BP","GO:0010887","negative regulation of cholesterol storage","6/173","11/21081",1.25032593323149e-10,9.89317484227298e-10,3.85281263753778e-10,"PPARA/CES1/CES1/NR1H3/PPARG/NR1H2",6
"GO:0070434","BP","GO:0070434","positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway","6/173","11/21081",1.25032593323149e-10,9.89317484227298e-10,3.85281263753778e-10,"TLR4/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",6
"GO:0050803","BP","GO:0050803","regulation of synapse structure or activity","17/173","275/21081",1.25986818712934e-10,9.95014856340629e-10,3.87500056773103e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/LRRK2/PTK2/SNCA/RHOA/ABL1/MAPK14/APP/VCP",17
"GO:0048016","BP","GO:0048016","inositol phosphate-mediated signaling","10/173","65/21081",1.29351963194891e-10,1.01780831780572e-09,3.96376776105981e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GSK3B/MTOR",10
"GO:0060135","BP","GO:0060135","maternal process involved in female pregnancy","10/173","65/21081",1.29351963194891e-10,1.01780831780572e-09,3.96376776105981e-10,"MAPK3/ESR1/CNR1/PTGS2/MTOR/MAPK1/AKT1/AKR1B1/CTSB/CTSB",10
"GO:0055074","BP","GO:0055074","calcium ion homeostasis","22/173","496/21081",1.34266090277128e-10,1.05452239849818e-09,4.10674761972265e-10,"ESR1/DRD2/CNR1/CXCR3/AGTR1/PRKCB/DRD3/TACR1/HTR2A/PIK3CG/NOS1/SNCA/F2/GLP1R/ABL1/APP/CD38/IL2/C5AR1/ELANE/ELANE/PSEN1",22
"GO:0045123","BP","GO:0045123","cellular extravasation","11/173","87/21081",1.34814933607315e-10,1.05687943339019e-09,4.11592689125459e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PIK3CG/ELANE/ELANE",11
"GO:0007431","BP","GO:0007431","salivary gland development","9/173","47/21081",1.42786654154712e-10,1.11525826011649e-09,4.3432782571828e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/EGFR",9
"GO:0030866","BP","GO:0030866","cortical actin cytoskeleton organization","9/173","47/21081",1.42786654154712e-10,1.11525826011649e-09,4.3432782571828e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IKBKB",9
"GO:0071248","BP","GO:0071248","cellular response to metal ion","15/173","204/21081",1.4524594495587e-10,1.13238535801374e-09,4.40997828045635e-10,"FABP4/MAPK3/BACE1/MAPK8/PTGS2/NQO1/MAPK1/CHUK/AKT1/PARP1/LRRK2/EGFR/SNCA/MMP9/APP",15
"GO:0045670","BP","GO:0045670","regulation of osteoclast differentiation","11/173","88/21081",1.52988960848845e-10,1.18961352035623e-09,4.63284848199576e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MTOR/TLR4/ESRRA",11
"GO:1903076","BP","GO:1903076","regulation of protein localization to plasma membrane","12/173","113/21081",1.53146292218136e-10,1.18961352035623e-09,4.63284848199576e-10,"BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CSK/AKT1/EGFR",12
"GO:0019693","BP","GO:0019693","ribose phosphate metabolic process","21/173","452/21081",1.565213481389e-10,1.2136116938726e-09,4.72630732374858e-10,"G6PD/PPARA/HMGCR/RORA/PDE4A/HTR2A/PARP1/LRRK2/HDAC4/INSR/RHOA/STAT3/APP/PFKFB3/FASN/ACACA/ACACA/OGT/VCP/EP300/PSEN1",21
"GO:0060326","BP","GO:0060326","cell chemotaxis","19/173","362/21081",1.60559921175282e-10,1.24265775058975e-09,4.83942471647097e-10,"CYP19A1/MAPK3/ALOX5/ALOX5/SERPINE1/CXCR3/IL6/AGTR1/PIK3CG/MAPK1/PTK2/MIF/MIF/CXCL8/MAPK14/ABCC1/ABCC1/DPP4/C5AR1",19
"GO:0120254","BP","GO:0120254","olefinic compound metabolic process","13/173","142/21081",1.68991170158409e-10,1.30553360364196e-09,5.08428936821089e-10,"CYP19A1/SRD5A1/MAPK3/PTGS1/ALOX5/ALOX5/PTGS2/AKR1C1/CBR1/STAT5B/EPHX1/CYP1B1/MGLL",13
"GO:0006909","BP","GO:0006909","phagocytosis","20/173","408/21081",1.72300800974073e-10,1.32868621295614e-09,5.17445523223312e-10,"MAPK3/NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/SRC/CSK/PIK3CA/MAPK1/TLR4/PTK2/ABL1/ELANE/ELANE",20
"GO:0002437","BP","GO:0002437","inflammatory response to antigenic stimulus","11/173","89/21081",1.73334764889271e-10,1.33423807249006e-09,5.1960764760857e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CNR1/ELANE/ELANE",11
"GO:2000008","BP","GO:2000008","regulation of protein localization to cell surface","9/173","48/21081",1.74507851467059e-10,1.34083880810766e-09,5.22178247846611e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/AKT1",9
"GO:0045930","BP","GO:0045930","negative regulation of mitotic cell cycle","20/173","409/21081",1.79892760918212e-10,1.3797190273312e-09,5.37319817905052e-10,"BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MDM2/CDK2/PRMT1/CHEK2/CDK4/WEE1/EGFR/CCND1/ABL1/CDK1/EP300",20
"GO:1901222","BP","GO:1901222","regulation of NIK/NF-kappaB signaling","13/173","144/21081",2.01463574975541e-10,1.54237609021815e-09,6.00665224962636e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TLR4/EGFR/RHOA/APP/EP300",13
"GO:0032869","BP","GO:0032869","cellular response to insulin stimulus","16/173","245/21081",2.02013157650623e-10,1.5438019907509e-09,6.0122052977429e-10,"NR1H4/SRD5A1/PTPN11/IGF1R/PPARG/PRKCB/SRC/GSK3B/PIK3CA/CDK4/AKT1/PARP1/INSR/SIRT1/ESRRA/OGT",16
"GO:0002922","BP","GO:0002922","positive regulation of humoral immune response","8/173","33/21081",2.03806477085752e-10,1.55471045087497e-09,6.05468736613062e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0007565","BP","GO:0007565","female pregnancy","15/173","209/21081",2.04217406995685e-10,1.5550533374994e-09,6.05602270887033e-10,"MAPK3/ESR1/IDO1/CNR1/PTGS2/MTOR/MAPK1/AKT1/AKR1B1/CTSB/CTSB/MMP9/STAT5B/MMP2/CD38",15
"GO:0030865","BP","GO:0030865","cortical cytoskeleton organization","10/173","68/21081",2.05695092072548e-10,1.56350348160332e-09,6.0889310750032e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IKBKB/RHOA",10
"GO:2000060","BP","GO:2000060","positive regulation of ubiquitin-dependent protein catabolic process","12/173","116/21081",2.08676791824351e-10,1.58333515796726e-09,6.16616384864435e-10,"MDM2/GSK3B/AKT1/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/PTK2/VCP/PSEN1",12
"GO:0032355","BP","GO:0032355","response to estradiol","13/173","145/21081",2.19742931809875e-10,1.66432748174716e-09,6.48158155183643e-10,"CYP19A1/SRD5A1/ESR1/ESR2/PTGS2/NQO1/CCNA2/EGFR/CCND1/STAT5B/STAT3/ESRRA/CD38",13
"GO:0010878","BP","GO:0010878","cholesterol storage","7/173","21/21081",2.34206262511448e-10,1.77071603098068e-09,6.89590269091584e-10,"PPARA/CES1/CES1/NR1H3/SREBF2/PPARG/NR1H2",7
"GO:0034976","BP","GO:0034976","response to endoplasmic reticulum stress","18/173","328/21081",2.44295671925846e-10,1.84371635881513e-09,7.18019624693707e-10,"ALOX5/ALOX5/BCL2L1/NR1H3/NR1H2/GSK3B/LRRK2/CCND1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/CXCL8/SIRT1/CFTR/VCP/EP300",18
"GO:0032075","BP","GO:0032075","positive regulation of nuclease activity","6/173","12/21081",2.48367587841272e-10,1.86781217829658e-09,7.27403536257998e-10,"AKT1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",6
"GO:0070426","BP","GO:0070426","positive regulation of nucleotide-binding oligomerization domain containing signaling pathway","6/173","12/21081",2.48367587841272e-10,1.86781217829658e-09,7.27403536257998e-10,"TLR4/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",6
"GO:0010565","BP","GO:0010565","regulation of cellular ketone metabolic process","15/173","212/21081",2.49433041705939e-10,1.87175801305804e-09,7.2894020798138e-10,"NR1H4/FABP5/PPARA/FABP1/CES1/CES1/NR1H3/CNR1/PPARG/PTGS2/NR1H2/MTOR/NQO1/AKT1/SIRT1",15
"GO:0043470","BP","GO:0043470","regulation of carbohydrate catabolic process","11/173","92/21081",2.49773309814994e-10,1.87175801305804e-09,7.2894020798138e-10,"PPARA/HTR2A/HDAC4/INSR/PPP1CA/STAT3/APP/PFKFB3/OGT/EP300/PSEN1",11
"GO:0042220","BP","GO:0042220","response to cocaine","9/173","50/21081",2.57062629917802e-10,1.9162440605627e-09,7.46264920093785e-10,"SLC6A3/SLC6A3/DRD2/CNR1/MDM2/DRD3/HTR2A/MTOR/CCNA2",9
"GO:0048566","BP","GO:0048566","embryonic digestive tract development","9/173","50/21081",2.57062629917802e-10,1.9162440605627e-09,7.46264920093785e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CXCL8",9
"GO:1901031","BP","GO:1901031","regulation of response to reactive oxygen species","9/173","50/21081",2.57062629917802e-10,1.9162440605627e-09,7.46264920093785e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/LRRK2",9
"GO:0038127","BP","GO:0038127","ERBB signaling pathway","13/173","147/21081",2.60901907394845e-10,1.94145745099947e-09,7.56084060143232e-10,"PTPN11/SRC/ERBB2/PRKCA/PIK3CA/MAPK1/AKT1/EGFR/PTK2/MMP9/ABL1/APP/PSEN1",13
"GO:0010758","BP","GO:0010758","regulation of macrophage chemotaxis","8/173","34/21081",2.64663375926755e-10,1.95915450228707e-09,7.62976025961596e-10,"CYP19A1/MAPK3/MAPK1/PTK2/MIF/MIF/MAPK14/C5AR1",8
"GO:0045662","BP","GO:0045662","negative regulation of myoblast differentiation","8/173","34/21081",2.64663375926755e-10,1.95915450228707e-09,7.62976025961596e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0045672","BP","GO:0045672","positive regulation of osteoclast differentiation","8/173","34/21081",2.64663375926755e-10,1.95915450228707e-09,7.62976025961596e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0009411","BP","GO:0009411","response to UV","13/173","148/21081",2.840072864364e-10,2.09869036533611e-09,8.17317078769832e-10,"MAPK8/MDM2/PTGS2/AKT1/PARP1/EGFR/CCND1/MC1R/SIRT1/TYR/ELANE/ELANE/EP300",13
"GO:0007611","BP","GO:0007611","learning or memory","17/173","291/21081",3.02758147896447e-10,2.23336696252084e-09,8.69765731895494e-10,"HMGCR/DRD2/CNR1/PTGS2/DRD3/HTR2A/MTOR/MAPK1/EGFR/INSR/GLP1R/APP/MAPT/MAPT/MAPT/EP300/PSEN1",17
"GO:0045931","BP","GO:0045931","positive regulation of mitotic cell cycle","14/173","181/21081",3.12852509280527e-10,2.30383069659092e-09,8.97207232671693e-10,"PTPN11/TERT/MDM2/DRD3/PRKCA/CDK4/AKT1/EGFR/CCND1/INSR/STAT5B/ABL1/CDK1/APP",14
"GO:0014015","BP","GO:0014015","positive regulation of gliogenesis","11/173","94/21081",3.16319180858924e-10,2.32532906482625e-09,9.05579588982388e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/IL6/MTOR",11
"GO:1903078","BP","GO:1903078","positive regulation of protein localization to plasma membrane","10/173","71/21081",3.1982395141265e-10,2.347032762612e-09,9.1403190913678e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/AKT1/EGFR",10
"GO:0009150","BP","GO:0009150","purine ribonucleotide metabolic process","20/173","426/21081",3.67480810635677e-10,2.69211373170861e-09,1.04842075194062e-09,"PPARA/HMGCR/RORA/PDE4A/HTR2A/PARP1/LRRK2/HDAC4/INSR/RHOA/STAT3/APP/PFKFB3/FASN/ACACA/ACACA/OGT/VCP/EP300/PSEN1",20
"GO:0043123","BP","GO:0043123","positive regulation of I-kappaB kinase/NF-kappaB signaling","15/173","218/21081",3.68573538192461e-10,2.69547153834727e-09,1.04972842112247e-09,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRKCB/IKBKB/CHUK/AKT1/TLR4/RHOA/ABL1",15
"GO:1904646","BP","GO:1904646","cellular response to amyloid-beta","9/173","52/21081",3.72217551219218e-10,2.71744394352313e-09,1.05828538708014e-09,"BACE1/IGF1R/GSK3B/PARP1/TLR4/ABCC1/ABCC1/APP/PSEN1",9
"GO:1901570","BP","GO:1901570","fatty acid derivative biosynthetic process","12/173","122/21081",3.77441146426399e-10,2.75085322669943e-09,1.07129634771563e-09,"FABP5/PTGS1/ALOX5/ALOX5/PTGS2/MIF/MIF/CBR1/SIRT1/FASN/ACACA/ACACA",12
"GO:0030336","BP","GO:0030336","negative regulation of cell migration","19/173","385/21081",4.53263626800463e-10,3.29780333951227e-09,1.28430140830989e-09,"CYP19A1/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/PPARG/AKT1/MIF/MIF/RHOA/STAT3/CYP1B1/DPP4",19
"GO:0046777","BP","GO:0046777","protein autophosphorylation","16/173","259/21081",4.57647504802961e-10,3.32400726138082e-09,1.29450630238462e-09,"MAPK3/IGF1R/SRC/GSK3B/ERBB2/CSK/CHEK2/MTOR/PIM1/AKT1/LRRK2/EGFR/INSR/PTK2/ACE/ABL1",16
"GO:0070266","BP","GO:0070266","necroptotic process","9/173","54/21081",5.30522497687101e-10,3.84674077247866e-09,1.49808041380299e-09,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TLR4",9
"GO:0042752","BP","GO:0042752","regulation of circadian rhythm","12/173","126/21081",5.50346615583353e-10,3.96910701660440e-09,1.54573490483262e-09,"PPARA/RORA/NR1H3/MAPK8/DRD2/PPARG/DRD3/GSK3B/MTOR/PPP1CA/MAPK10/CDK1",12
"GO:0034116","BP","GO:0034116","positive regulation of heterotypic cell-cell adhesion","8/173","37/21081",5.51135123510613e-10,3.96910701660440e-09,1.54573490483262e-09,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0060441","BP","GO:0060441","epithelial tube branching involved in lung morphogenesis","8/173","37/21081",5.51135123510613e-10,3.96910701660440e-09,1.54573490483262e-09,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:1902235","BP","GO:1902235","regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway","8/173","37/21081",5.51135123510613e-10,3.96910701660440e-09,1.54573490483262e-09,"BCL2L1/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SIRT1",8
"GO:0032436","BP","GO:0032436","positive regulation of proteasomal ubiquitin-dependent protein catabolic process","11/173","99/21081",5.5745133148476e-10,4.00103160047086e-09,1.55816766197376e-09,"MDM2/GSK3B/AKT1/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/VCP/PSEN1",11
"GO:0045445","BP","GO:0045445","myoblast differentiation","11/173","99/21081",5.5745133148476e-10,4.00103160047086e-09,1.55816766197376e-09,"PLG/HMGCR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MAPK14",11
"GO:1902991","BP","GO:1902991","regulation of amyloid precursor protein catabolic process","9/173","55/21081",6.29883265432325e-10,4.51327823747377e-09,1.75765774963986e-09,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/APP",9
"GO:0032652","BP","GO:0032652","regulation of interleukin-1 production","13/173","158/21081",6.41268221343087e-10,4.58711897725047e-09,1.78641439651131e-09,"NR1H4/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/TLR4/STAT3/APP",13
"GO:0018107","BP","GO:0018107","peptidyl-threonine phosphorylation","12/173","128/21081",6.61220371266788e-10,4.72189135716401e-09,1.8389003514045e-09,"MAPK8/PRKCB/GSK3B/PRKCA/CSNK2A1/CSNK2A2/MTOR/MAPK1/AKT1/LRRK2/CDK1/APP",12
"GO:0009259","BP","GO:0009259","ribonucleotide metabolic process","20/173","441/21081",6.71227445353501e-10,4.78531109950843e-09,1.86359862962858e-09,"PPARA/HMGCR/RORA/PDE4A/HTR2A/PARP1/LRRK2/HDAC4/INSR/RHOA/STAT3/APP/PFKFB3/FASN/ACACA/ACACA/OGT/VCP/EP300/PSEN1",20
"GO:0007584","BP","GO:0007584","response to nutrient","14/173","192/21081",6.81357570681632e-10,4.84939416721316e-09,1.88855523426171e-09,"NR1H4/HMGCR/CNR1/MDM2/PPARG/PTGS2/MTOR/NQO1/PIM1/CYP26A1/EGFR/CCND1/TYR/OGT",14
"GO:0045216","BP","GO:0045216","cell-cell junction organization","15/173","228/21081",6.87949084104785e-10,4.8881198300355e-09,1.90363661364676e-09,"NR1H4/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SRC/PRKCA/IKBKB/CSK/ACE/RHOA",15
"GO:0022617","BP","GO:0022617","extracellular matrix disassembly","11/173","101/21081",6.93037791484027e-10,4.91605605344847e-09,1.91451613779614e-09,"PLG/IL6/MMP3/MMP9/CTSG/MMP2/MMP13/MMP12/DPP4/ELANE/ELANE",11
"GO:0046394","BP","GO:0046394","carboxylic acid biosynthetic process","19/173","395/21081",6.95711113329016e-10,4.92679420089165e-09,1.91869801781266e-09,"NR1H4/FABP5/PTGS1/CES1/CES1/ALOX5/ALOX5/IDO1/NR1H3/PTGS2/NR1H2/MIF/MIF/CBR1/SIRT1/FASN/MGLL/ACACA/ACACA",19
"GO:0016053","BP","GO:0016053","organic acid biosynthetic process","19/173","396/21081",7.25649259822515e-10,5.13025574872856e-09,1.99793438381819e-09,"NR1H4/FABP5/PTGS1/CES1/CES1/ALOX5/ALOX5/IDO1/NR1H3/PTGS2/NR1H2/MIF/MIF/CBR1/SIRT1/FASN/MGLL/ACACA/ACACA",19
"GO:0030324","BP","GO:0030324","lung development","14/173","193/21081",7.29463823324447e-10,5.14865745067372e-09,2.00510076983045e-09,"MAPK3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MAPK1/NOS3/EGFR/PPP1CA/EP300",14
"GO:0070432","BP","GO:0070432","regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway","6/173","14/21081",7.96274044588605e-10,5.61089289462186e-09,2.18511442453223e-09,"TLR4/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",6
"GO:0038061","BP","GO:0038061","NIK/NF-kappaB signaling","15/173","231/21081",8.24525578719719e-10,5.80034633109286e-09,2.25889545093656e-09,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CHUK/AKT1/TLR4/EGFR/RHOA/APP/EP300",15
"GO:1904377","BP","GO:1904377","positive regulation of protein localization to cell periphery","10/173","78/21081",8.2961145116713e-10,5.8264777785275e-09,2.2690721204606e-09,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/AKT1/EGFR",10
"GO:0019217","BP","GO:0019217","regulation of fatty acid metabolic process","11/173","103/21081",8.5748460590216e-10,6.01229717900706e-09,2.34143790251554e-09,"FABP5/PPARA/FABP1/NR1H3/CNR1/PPARG/PTGS2/NR1H2/MTOR/AKT1/SIRT1",11
"GO:0007043","BP","GO:0007043","cell-cell junction assembly","13/173","162/21081",8.73929269188615e-10,6.1175048843203e-09,2.3824101468213e-09,"NR1H4/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRKCA/IKBKB/ACE/RHOA",13
"GO:0002861","BP","GO:0002861","regulation of inflammatory response to antigenic stimulus","9/173","57/21081",8.78793766539598e-10,6.12130280987992e-09,2.38388921656643e-09,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CNR1",9
"GO:0006584","BP","GO:0006584","catecholamine metabolic process","9/173","57/21081",8.78793766539598e-10,6.12130280987992e-09,2.38388921656643e-09,"SLC6A3/SLC6A3/DRD2/DRD3/HTR1A/MAOA/AKR1B1/SNCA/MAOB",9
"GO:0009712","BP","GO:0009712","catechol-containing compound metabolic process","9/173","57/21081",8.78793766539598e-10,6.12130280987992e-09,2.38388921656643e-09,"SLC6A3/SLC6A3/DRD2/DRD3/HTR1A/MAOA/AKR1B1/SNCA/MAOB",9
"GO:2000146","BP","GO:2000146","negative regulation of cell motility","19/173","401/21081",8.94115313978181e-10,6.21783300997265e-09,2.42148208040951e-09,"CYP19A1/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/PPARG/AKT1/MIF/MIF/RHOA/STAT3/CYP1B1/DPP4",19
"GO:0030595","BP","GO:0030595","leukocyte chemotaxis","16/173","272/21081",9.35250183080673e-10,6.49326475148656e-09,2.52874662504785e-09,"CYP19A1/MAPK3/ALOX5/ALOX5/SERPINE1/CXCR3/IL6/PIK3CG/MAPK1/PTK2/MIF/MIF/CXCL8/MAPK14/DPP4/C5AR1",16
"GO:1902236","BP","GO:1902236","negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway","7/173","25/21081",9.41815387071443e-10,6.51633094745826e-09,2.53772955851021e-09,"BCL2L1/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",7
"GO:0006695","BP","GO:0006695","cholesterol biosynthetic process","10/173","79/21081",9.43173342595159e-10,6.51633094745826e-09,2.53772955851021e-09,"NPC1L1/G6PD/HMGCR/CES1/CES1/SREBF2/CFTR/FASN/ACACA/ACACA",10
"GO:1902653","BP","GO:1902653","secondary alcohol biosynthetic process","10/173","79/21081",9.43173342595159e-10,6.51633094745826e-09,2.53772955851021e-09,"NPC1L1/G6PD/HMGCR/CES1/CES1/SREBF2/CFTR/FASN/ACACA/ACACA",10
"GO:1901655","BP","GO:1901655","cellular response to ketone","11/173","104/21081",9.52154431222762e-10,6.56770158809337e-09,2.55773541675014e-09,"SRD5A1/PPARG/SRC/CDK4/AKT1/EGFR/AKR1B1/SIRT1/CFTR/ACACA/ACACA",11
"GO:0030323","BP","GO:0030323","respiratory tube development","14/173","197/21081",9.54522569137779e-10,6.57336530999421e-09,2.55994110498096e-09,"MAPK3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MAPK1/NOS3/EGFR/PPP1CA/EP300",14
"GO:0051098","BP","GO:0051098","regulation of binding","19/173","405/21081",1.05428220926232e-09,7.24861667824532e-09,2.82291199618527e-09,"PPARA/MAPK3/TERT/MAPK8/PPARG/SRC/GSK3B/AKT1/PARP1/LRRK2/HDAC4/ACE/PPP1CA/MMP9/ABL1/APP/PPP2CA/EP300/PSEN1",19
"GO:0001885","BP","GO:0001885","endothelial cell development","10/173","80/21081",1.07034135664962e-09,7.34714123490182e-09,2.86128154519718e-09,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IKBKB/FASN",10
"GO:1903522","BP","GO:1903522","regulation of blood circulation","17/173","317/21081",1.12324095147279e-09,7.69782387549656e-09,2.99785191123127e-09,"DRD2/MDM2/PTGS2/AGTR1/HTR2A/PIK3CG/NOS3/AKT1/NOS1/EGFR/HDAC4/ACE/RHOA/GLP1R/CD38/IL2/CACNA1B",17
"GO:0008203","BP","GO:0008203","cholesterol metabolic process","13/173","166/21081",1.18084578065131e-09,8.07957121092979e-09,3.14652015795212e-09,"NPC1L1/G6PD/NR1H4/HMGCR/CES1/CES1/SREBF2/APP/CFTR/FASN/ACACA/ACACA/CETP",13
"GO:0097300","BP","GO:0097300","programmed necrotic cell death","9/173","59/21081",1.21033166527875e-09,8.2680052182788e-09,3.21990417637197e-09,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TLR4",9
"GO:0006110","BP","GO:0006110","regulation of glycolytic process","10/173","81/21081",1.21251712571049e-09,8.26963927310411e-09,3.22054054509907e-09,"PPARA/HTR2A/HDAC4/INSR/STAT3/APP/PFKFB3/OGT/EP300/PSEN1",10
"GO:1904375","BP","GO:1904375","regulation of protein localization to cell periphery","12/173","135/21081",1.22645302153441e-09,8.35128027003161e-09,3.25233493564794e-09,"BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CSK/AKT1/EGFR",12
"GO:0032069","BP","GO:0032069","regulation of nuclease activity","7/173","26/21081",1.27992819014692e-09,8.70146380789481e-09,3.38871093037635e-09,"AKT1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SIRT1",7
"GO:0002719","BP","GO:0002719","negative regulation of cytokine production involved in immune response","8/173","41/21081",1.32644022643299e-09,8.98890673383374e-09,3.50065312843558e-09,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0031116","BP","GO:0031116","positive regulation of microtubule polymerization","8/173","41/21081",1.32644022643299e-09,8.98890673383374e-09,3.50065312843558e-09,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/MAPT/MAPT/MAPT",8
"GO:0032612","BP","GO:0032612","interleukin-1 production","13/173","168/21081",1.36840545906582e-09,9.25852674453929e-09,3.60565434403532e-09,"NR1H4/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/TLR4/STAT3/APP",13
"GO:0044706","BP","GO:0044706","multi-multicellular organism process","15/173","240/21081",1.39716685653047e-09,9.4380953472146e-09,3.67558580615163e-09,"MAPK3/ESR1/IDO1/CNR1/PTGS2/MTOR/MAPK1/AKT1/AKR1B1/CTSB/CTSB/MMP9/STAT5B/MMP2/CD38",15
"GO:0002714","BP","GO:0002714","positive regulation of B cell mediated immunity","9/173","60/21081",1.4139608118762e-09,9.52126702006654e-09,3.7079763053956e-09,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL2",9
"GO:0002891","BP","GO:0002891","positive regulation of immunoglobulin mediated immune response","9/173","60/21081",1.4139608118762e-09,9.52126702006654e-09,3.7079763053956e-09,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL2",9
"GO:0018210","BP","GO:0018210","peptidyl-threonine modification","12/173","137/21081",1.4535533278292e-09,9.77238621826939e-09,3.80577253722101e-09,"MAPK8/PRKCB/GSK3B/PRKCA/CSNK2A1/CSNK2A2/MTOR/MAPK1/AKT1/LRRK2/CDK1/APP",12
"GO:0007254","BP","GO:0007254","JNK cascade","15/173","241/21081",1.4793900106182e-09,9.93037623241188e-09,3.86730040191537e-09,"IGF1R/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MAPK8/AKT1/TLR4/EGFR/MAPK10/APP",15
"GO:2001235","BP","GO:2001235","positive regulation of apoptotic signaling pathway","14/173","205/21081",1.60474095944959e-09,1.07548017929043e-08,4.18836591109873e-09,"BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MAPK8/GSK3B/PPP1CA/MMP9/SIRT1",14
"GO:0001990","BP","GO:0001990","regulation of systemic arterial blood pressure by hormone","8/173","42/21081",1.62715726444466e-09,1.0887860183662e-08,4.24018436752095e-09,"CES1/CES1/AGTR1/DRD3/NOS3/ACE/RHOA/CTSG",8
"GO:2001238","BP","GO:2001238","positive regulation of extrinsic apoptotic signaling pathway","9/173","61/21081",1.64708445255327e-09,1.10038708158787e-08,4.28536371965199e-09,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPP1CA",9
"GO:0048639","BP","GO:0048639","positive regulation of developmental growth","14/173","206/21081",1.70960212532242e-09,1.14036097809968e-08,4.44103865323779e-09,"SLC6A3/SLC6A3/DRD2/MTOR/MAPK1/PIM1/AKT1/INSR/STAT5B/MAPK14/CDK1/MAPT/MAPT/MAPT",14
"GO:0002637","BP","GO:0002637","regulation of immunoglobulin production","10/173","84/21081",1.744974684952e-09,1.15309446910747e-08,4.49062814888197e-09,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/IL2",10
"GO:0032515","BP","GO:0032515","negative regulation of phosphoprotein phosphatase activity","10/173","84/21081",1.744974684952e-09,1.15309446910747e-08,4.49062814888197e-09,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GSK3B/IKBKB",10
"GO:0045913","BP","GO:0045913","positive regulation of carbohydrate metabolic process","10/173","84/21081",1.744974684952e-09,1.15309446910747e-08,4.49062814888197e-09,"PPARA/SRC/HTR2A/AKT1/INSR/SNCA/SIRT1/APP/PFKFB3/PSEN1",10
"GO:0051881","BP","GO:0051881","regulation of mitochondrial membrane potential","10/173","84/21081",1.744974684952e-09,1.15309446910747e-08,4.49062814888197e-09,"BCL2L1/SRC/AKT1/PARP1/LRRK2/ABL1/MAPT/MAPT/MAPT/VCP",10
"GO:1900182","BP","GO:1900182","positive regulation of protein localization to nucleus","10/173","84/21081",1.744974684952e-09,1.15309446910747e-08,4.49062814888197e-09,"TERT/PTGS2/SRC/MAPK1/AKT1/PARP1/F2/MAPK14/CDK1/PSEN1",10
"GO:1902117","BP","GO:1902117","positive regulation of organelle assembly","10/173","84/21081",1.744974684952e-09,1.15309446910747e-08,4.49062814888197e-09,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SRC/RHOA",10
"GO:0006836","BP","GO:0006836","neurotransmitter transport","15/173","244/21081",1.75337646937028e-09,1.1568473009867e-08,4.50524323283767e-09,"SLC6A3/SLC6A3/BACE1/DRD2/CNR1/PRKCB/DRD3/GSK3B/HTR2A/CHRNA3/NOS1/LRRK2/SNCA/CACNA1B/PSEN1",15
"GO:0032651","BP","GO:0032651","regulation of interleukin-1 beta production","12/173","140/21081",1.86572299169275e-09,1.22716052503134e-08,4.77907209213133e-09,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/TLR4/STAT3/APP",12
"GO:1905477","BP","GO:1905477","positive regulation of protein localization to membrane","12/173","140/21081",1.86572299169275e-09,1.22716052503134e-08,4.77907209213133e-09,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MAPK8/ERBB2/AKT1/EGFR",12
"GO:0045646","BP","GO:0045646","regulation of erythrocyte differentiation","9/173","62/21081",1.91330317115696e-09,1.25457178614906e-08,4.88582291270102e-09,"PRMT1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/STAT5B/STAT3/MAPK14",9
"GO:0045661","BP","GO:0045661","regulation of myoblast differentiation","9/173","62/21081",1.91330317115696e-09,1.25457178614906e-08,4.88582291270102e-09,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MAPK14",9
"GO:0043279","BP","GO:0043279","response to alkaloid","11/173","111/21081",1.92270306977837e-09,1.25694255418126e-08,4.89505566677716e-09,"SLC6A3/SLC6A3/BCL2L1/DRD2/CNR1/MDM2/PPARG/DRD3/HTR2A/MTOR/CCNA2",11
"GO:0042742","BP","GO:0042742","defense response to bacterium","19/173","420/21081",1.92283516172703e-09,1.25694255418126e-08,4.89505566677716e-09,"NR1H4/NOS2/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/TLR4/F2/MPO/CTSG/C5AR1/ELANE/ELANE",19
"GO:0016126","BP","GO:0016126","sterol biosynthetic process","10/173","85/21081",1.96374888945633e-09,1.28171567301074e-08,4.99153246701488e-09,"NPC1L1/G6PD/HMGCR/CES1/CES1/SREBF2/CFTR/FASN/ACACA/ACACA",10
"GO:0042417","BP","GO:0042417","dopamine metabolic process","8/173","43/21081",1.98518763384182e-09,1.29372120493772e-08,5.0382869880519e-09,"SLC6A3/SLC6A3/DRD2/DRD3/HTR1A/MAOA/SNCA/MAOB",8
"GO:1905475","BP","GO:1905475","regulation of protein localization to membrane","14/173","210/21081",2.19452667849702e-09,1.42795464884132e-08,5.56104769661854e-09,"BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MAPK8/ERBB2/CSK/AKT1/EGFR",14
"GO:0006636","BP","GO:0006636","unsaturated fatty acid biosynthetic process","9/173","63/21081",2.2165768101236e-09,1.44009707434483e-08,5.60833533802399e-09,"FABP5/PTGS1/ALOX5/ALOX5/PTGS2/MIF/MIF/CBR1/SIRT1",9
"GO:1902652","BP","GO:1902652","secondary alcohol metabolic process","13/173","175/21081",2.2575524977307e-09,1.46447947524546e-08,5.70329052058282e-09,"NPC1L1/G6PD/NR1H4/HMGCR/CES1/CES1/SREBF2/APP/CFTR/FASN/ACACA/ACACA/CETP",13
"GO:0003081","BP","GO:0003081","regulation of systemic arterial blood pressure by renin-angiotensin","7/173","28/21081",2.27226459665727e-09,1.47177626085316e-08,5.73170723033573e-09,"CES1/CES1/AGTR1/DRD3/ACE/RHOA/CTSG",7
"GO:0022612","BP","GO:0022612","gland morphogenesis","12/173","143/21081",2.38048212282495e-09,1.53952336984524e-08,5.9955425732289e-09,"ESR1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/SRC/EGFR",12
"GO:0046456","BP","GO:0046456","icosanoid biosynthetic process","9/173","64/21081",2.56125238121129e-09,1.65391510148431e-08,6.44103142419476e-09,"FABP5/PTGS1/ALOX5/ALOX5/PTGS2/MIF/MIF/CBR1/SIRT1",9
"GO:0043666","BP","GO:0043666","regulation of phosphoprotein phosphatase activity","12/173","144/21081",2.578574718084e-09,1.66257419986934e-08,6.47475354496934e-09,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/GSK3B/IKBKB/MTOR",12
"GO:0007204","BP","GO:0007204","positive regulation of cytosolic calcium ion concentration","17/173","335/21081",2.59044235391116e-09,1.66769538814675e-08,6.49469757631315e-09,"ESR1/DRD2/CNR1/CXCR3/AGTR1/DRD3/TACR1/HTR2A/PIK3CG/NOS1/SNCA/F2/GLP1R/ABL1/CD38/IL2/C5AR1",17
"GO:0050805","BP","GO:0050805","negative regulation of synaptic transmission","10/173","88/21081",2.77335377201854e-09,1.78005742859619e-08,6.93228196790133e-09,"DRD2/PTGS2/DRD3/HTR2A/LRRK2/SNCA/CD38/MAPT/MAPT/MAPT",10
"GO:0097756","BP","GO:0097756","negative regulation of blood vessel diameter","10/173","88/21081",2.77335377201854e-09,1.78005742859619e-08,6.93228196790133e-09,"HMGCR/PTGS2/AGTR1/HTR1A/HTR2A/AKT1/EGFR/ACE/RHOA/CD38",10
"GO:0002688","BP","GO:0002688","regulation of leukocyte chemotaxis","12/173","145/21081",2.79140164616886e-09,1.78893900370611e-08,6.96687050532262e-09,"CYP19A1/MAPK3/SERPINE1/IL6/MAPK1/PTK2/MIF/MIF/CXCL8/MAPK14/DPP4/C5AR1",12
"GO:2000181","BP","GO:2000181","negative regulation of blood vessel morphogenesis","14/173","214/21081",2.80177997466118e-09,1.79288601089388e-08,6.98224178847079e-09,"ALOX5/ALOX5/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/XDH/RHOA",14
"GO:0031112","BP","GO:0031112","positive regulation of microtubule polymerization or depolymerization","8/173","45/21081",2.91008862135553e-09,1.85660158440535e-08,7.23037665998246e-09,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/MAPT/MAPT/MAPT",8
"GO:0110111","BP","GO:0110111","negative regulation of animal organ morphogenesis","8/173","45/21081",2.91008862135553e-09,1.85660158440535e-08,7.23037665998246e-09,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0045668","BP","GO:0045668","negative regulation of osteoblast differentiation","9/173","65/21081",2.95209351982105e-09,1.88057651659965e-08,7.32374499038695e-09,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/HDAC4",9
"GO:0006766","BP","GO:0006766","vitamin metabolic process","12/173","146/21081",3.01992842767843e-09,1.91517550585159e-08,7.45848780567242e-09,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CYP26A1/CBR1/ABCC1/ABCC1",12
"GO:0035296","BP","GO:0035296","regulation of tube diameter","12/173","146/21081",3.01992842767843e-09,1.91517550585159e-08,7.45848780567242e-09,"HMGCR/PTGS2/AGTR1/HTR1A/HTR2A/NOS3/AKT1/NOS1/EGFR/ACE/RHOA/CD38",12
"GO:0097746","BP","GO:0097746","regulation of blood vessel diameter","12/173","146/21081",3.01992842767843e-09,1.91517550585159e-08,7.45848780567242e-09,"HMGCR/PTGS2/AGTR1/HTR1A/HTR2A/NOS3/AKT1/NOS1/EGFR/ACE/RHOA/CD38",12
"GO:0006446","BP","GO:0006446","regulation of translational initiation","10/173","89/21081",3.1024701020349e-09,1.96458948786085e-08,7.65092634779019e-09,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MTOR/PPP1CA",10
"GO:0010506","BP","GO:0010506","regulation of autophagy","18/173","385/21081",3.14025300532153e-09,1.98555580648976e-08,7.73257788904362e-09,"MAPK3/SREBF2/MAPK8/GSK3B/CSNK2A2/MTOR/PIK3CA/AKT1/LRRK2/PTK2/SNCA/SIRT1/ABL1/STAT3/MAPT/MAPT/MAPT/EP300",18
"GO:0035150","BP","GO:0035150","regulation of tube size","12/173","148/21081",3.52821945975009e-09,2.22754895757476e-08,8.6749995944743e-09,"HMGCR/PTGS2/AGTR1/HTR1A/HTR2A/NOS3/AKT1/NOS1/EGFR/ACE/RHOA/CD38",12
"GO:1903050","BP","GO:1903050","regulation of proteolysis involved in cellular protein catabolic process","15/173","258/21081",3.75690074970067e-09,2.3684082025932e-08,9.22356392086438e-09,"MDM2/GSK3B/CSNK2A1/CSNK2A2/AKT1/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/PTK2/OGT/VCP/PSEN1",15
"GO:0032611","BP","GO:0032611","interleukin-1 beta production","12/173","149/21081",3.81019846163651e-09,2.39490137033928e-08,9.32673930503362e-09,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/TLR4/STAT3/APP",12
"GO:1903052","BP","GO:1903052","positive regulation of proteolysis involved in cellular protein catabolic process","12/173","149/21081",3.81019846163651e-09,2.39490137033928e-08,9.32673930503362e-09,"MDM2/GSK3B/AKT1/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/PTK2/VCP/PSEN1",12
"GO:0006839","BP","GO:0006839","mitochondrial transport","16/173","300/21081",3.83990388141619e-09,2.41000762069976e-08,9.38556930978192e-09,"BCL2L1/SREBF2/MAPK8/GSK3B/CSNK2A2/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/STAT3/PSEN2/ACACA/ACACA/PSEN1",16
"GO:0035308","BP","GO:0035308","negative regulation of protein dephosphorylation","10/173","91/21081",3.86629983861949e-09,2.42299528234428e-08,9.43614865131165e-09,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GSK3B/IKBKB",10
"GO:0006367","BP","GO:0006367","transcription initiation from RNA polymerase II promoter","14/173","220/21081",4.00274480191653e-09,2.50481040697251e-08,9.75477068229252e-09,"NR1H4/PPARA/NR1I3/NR1I2/ESR1/ESR2/RORA/NR1H3/PPARG/NR1H2/CDK4/CCND1/ESRRA/CDK1",14
"GO:0002761","BP","GO:0002761","regulation of myeloid leukocyte differentiation","12/173","150/21081",4.11231230832957e-09,2.56959044089593e-08,1.00070510041704e-08,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRKCA/MTOR/TLR4/ESRRA",12
"GO:0051271","BP","GO:0051271","negative regulation of cellular component movement","19/173","440/21081",4.12017295483654e-09,2.57072171587378e-08,1.00114566581699e-08,"CYP19A1/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/PPARG/AKT1/MIF/MIF/RHOA/STAT3/CYP1B1/DPP4",19
"GO:0034114","BP","GO:0034114","regulation of heterotypic cell-cell adhesion","8/173","47/21081",4.18656643759663e-09,2.60831683186922e-08,1.01578676337427e-08,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:1902105","BP","GO:1902105","regulation of leukocyte differentiation","17/173","346/21081",4.20675984645277e-09,2.61706040813731e-08,1.01919187464341e-08,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/ERBB2/PRKCA/MTOR/TLR4/RHOA/STAT5B/ABL1/ESRRA/IL2",17
"GO:0044262","BP","GO:0044262","cellular carbohydrate metabolic process","16/173","303/21081",4.42615925777765e-09,2.74952495413702e-08,1.07077906328508e-08,"PPARA/RORA/SRC/GSK3B/MTOR/AKT1/HDAC4/AKR1B1/INSR/SNCA/PPP1CA/SIRT1/STAT3/PFKFB3/OGT/EP300",16
"GO:0060541","BP","GO:0060541","respiratory system development","14/173","222/21081",4.49694010731467e-09,2.78941584174891e-08,1.08631422953495e-08,"MAPK3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MAPK1/NOS3/EGFR/PPP1CA/EP300",14
"GO:0045667","BP","GO:0045667","regulation of osteoblast differentiation","12/173","152/21081",4.7820759813759e-09,2.95543331446421e-08,1.15096831956442e-08,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/HDAC4/PTK2/ESRRA",12
"GO:0015844","BP","GO:0015844","monoamine transport","10/173","93/21081",4.79240657487842e-09,2.95543331446421e-08,1.15096831956442e-08,"SLC6A3/SLC6A3/DRD2/CNR1/DRD3/HTR1A/HTR2A/NOS1/SNCA/MAOB",10
"GO:0046785","BP","GO:0046785","microtubule polymerization","10/173","93/21081",4.79240657487842e-09,2.95543331446421e-08,1.15096831956442e-08,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SNCA/ABL1/MAPT/MAPT/MAPT",10
"GO:1903351","BP","GO:1903351","cellular response to dopamine","10/173","93/21081",4.79240657487842e-09,2.95543331446421e-08,1.15096831956442e-08,"MAPK3/DRD2/DRD3/GSK3B/HTR1A/HTR2A/MAPK1/HTR4/LRRK2/ABL1",10
"GO:0042303","BP","GO:0042303","molting cycle","11/173","121/21081",4.83334689494364e-09,2.9720536840254e-08,1.15744098085938e-08,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/PTGS2/EGFR",11
"GO:0042633","BP","GO:0042633","hair cycle","11/173","121/21081",4.83334689494364e-09,2.9720536840254e-08,1.15744098085938e-08,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TERT/PTGS2/EGFR",11
"GO:0002367","BP","GO:0002367","cytokine production involved in immune response","13/173","187/21081",5.06055999877205e-09,3.10727159462174e-08,1.21010044388039e-08,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/TLR4/MIF/MIF/SIRT1",13
"GO:0019369","BP","GO:0019369","arachidonic acid metabolic process","9/173","69/21081",5.08875318250608e-09,3.1200739209911e-08,1.21508620078979e-08,"MAPK3/PTGS1/ALOX5/ALOX5/PTGS2/CBR1/EPHX1/CYP1B1/MGLL",9
"GO:0008286","BP","GO:0008286","insulin receptor signaling pathway","12/173","153/21081",5.15246623505492e-09,3.15458631595798e-08,1.22852675891193e-08,"NR1H4/PTPN11/IGF1R/PRKCB/SRC/GSK3B/PIK3CA/CDK4/AKT1/INSR/SIRT1/OGT",12
"GO:1903350","BP","GO:1903350","response to dopamine","10/173","94/21081",5.32527412178548e-09,3.25569636596641e-08,1.26790320627744e-08,"MAPK3/DRD2/DRD3/GSK3B/HTR1A/HTR2A/MAPK1/HTR4/LRRK2/ABL1",10
"GO:0002763","BP","GO:0002763","positive regulation of myeloid leukocyte differentiation","9/173","70/21081",5.79872494948484e-09,3.52991150578239e-08,1.3746939557518e-08,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRKCA",9
"GO:0040014","BP","GO:0040014","regulation of multicellular organism growth","9/173","70/21081",5.79872494948484e-09,3.52991150578239e-08,1.3746939557518e-08,"SLC6A3/SLC6A3/DRD2/DRD3/PIK3CA/CDK4/STAT5B/STAT3/APP",9
"GO:0046686","BP","GO:0046686","response to cadmium ion","9/173","70/21081",5.79872494948484e-09,3.52991150578239e-08,1.3746939557518e-08,"MAPK3/TERT/MAPK8/MAPK1/CHUK/AKT1/EGFR/MMP9/CDK1",9
"GO:0035264","BP","GO:0035264","multicellular organism growth","12/173","155/21081",5.97167226998959e-09,3.62999076898223e-08,1.41366897197856e-08,"PTPN11/SLC6A3/SLC6A3/DRD2/DRD3/MTOR/PIK3CA/CDK4/STAT5B/STAT3/APP/EP300",12
"GO:1901343","BP","GO:1901343","negative regulation of vasculature development","14/173","227/21081",5.98469552198511e-09,3.63271018184496e-08,1.41472802414445e-08,"ALOX5/ALOX5/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/XDH/RHOA",14
"GO:0001516","BP","GO:0001516","prostaglandin biosynthetic process","7/173","32/21081",6.28336401212441e-09,3.80313585292259e-08,1.48109884946162e-08,"FABP5/PTGS1/PTGS2/MIF/MIF/CBR1/SIRT1",7
"GO:0046457","BP","GO:0046457","prostanoid biosynthetic process","7/173","32/21081",6.28336401212441e-09,3.80313585292259e-08,1.48109884946162e-08,"FABP5/PTGS1/PTGS2/MIF/MIF/CBR1/SIRT1",7
"GO:0032434","BP","GO:0032434","regulation of proteasomal ubiquitin-dependent protein catabolic process","12/173","156/21081",6.42368862850591e-09,3.88253954232171e-08,1.5120219396588e-08,"MDM2/GSK3B/AKT1/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/OGT/VCP/PSEN1",12
"GO:0031397","BP","GO:0031397","negative regulation of protein ubiquitination","10/173","96/21081",6.55087208931491e-09,3.94817808617008e-08,1.53758431122106e-08,"MTOR/AKT1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/ABL1/OGT/PSEN1",10
"GO:0032092","BP","GO:0032092","positive regulation of protein binding","10/173","96/21081",6.55087208931491e-09,3.94817808617008e-08,1.53758431122106e-08,"TERT/GSK3B/LRRK2/ACE/MMP9/ABL1/APP/PPP2CA/EP300/PSEN1",10
"GO:0048771","BP","GO:0048771","tissue remodeling","13/173","192/21081",6.96192951728023e-09,4.1899771273263e-08,1.63175088730647e-08,"PLG/MDM2/IL6/SRC/PRKCA/CSK/NOS3/EGFR/ACE/MMP2/NOX4/CD38/IL2",13
"GO:0048246","BP","GO:0048246","macrophage chemotaxis","8/173","50/21081",6.9998660534351e-09,4.20090831370703e-08,1.63600794469224e-08,"CYP19A1/MAPK3/MAPK1/PTK2/MIF/MIF/MAPK14/C5AR1",8
"GO:1903580","BP","GO:1903580","positive regulation of ATP metabolic process","8/173","50/21081",6.9998660534351e-09,4.20090831370703e-08,1.63600794469224e-08,"HTR2A/INSR/STAT3/CDK1/APP/PFKFB3/VCP/PSEN1",8
"GO:0006090","BP","GO:0006090","pyruvate metabolic process","12/173","158/21081",7.42118451575915e-09,4.44302101699284e-08,1.73029667382115e-08,"PPARA/LDHB/HTR2A/HDAC4/INSR/STAT3/GLO1/APP/PFKFB3/OGT/EP300/PSEN1",12
"GO:0010906","BP","GO:0010906","regulation of glucose metabolic process","11/173","126/21081",7.42420551203793e-09,4.44302101699284e-08,1.73029667382115e-08,"PPARA/RORA/SRC/GSK3B/MTOR/AKT1/INSR/PPP1CA/SIRT1/OGT/EP300",11
"GO:0032874","BP","GO:0032874","positive regulation of stress-activated MAPK cascade","13/173","194/21081",7.88834045579854e-09,4.71414326254402e-08,1.83588292198021e-08,"HMGCR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRMT1/TLR4/XDH/APP",13
"GO:0001763","BP","GO:0001763","morphogenesis of a branching structure","14/173","232/21081",7.907447016918e-09,4.71892449085458e-08,1.83774493060247e-08,"ESR1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/SRC/LRRK2/PPP1CA/ABL1",14
"GO:0003158","BP","GO:0003158","endothelium development","12/173","159/21081",7.97038824178144e-09,4.74981481617522e-08,1.84977490456639e-08,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IKBKB/XDH/RHOA/FASN",12
"GO:0032963","BP","GO:0032963","collagen metabolic process","11/173","127/21081",8.07099774678308e-09,4.80303493362483e-08,1.87050102579139e-08,"CTSD/PPARG/IL6/F2/MMP3/CTSB/CTSB/MMP9/MMP2/MMP13/MMP12",11
"GO:0038083","BP","GO:0038083","peptidyl-tyrosine autophosphorylation","8/173","51/21081",8.24449904800779e-09,4.88575682775245e-08,1.90271636254397e-08,"MAPK3/IGF1R/SRC/EGFR/INSR/PTK2/ACE/ABL1",8
"GO:0045684","BP","GO:0045684","positive regulation of epidermis development","8/173","51/21081",8.24449904800779e-09,4.88575682775245e-08,1.90271636254397e-08,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:1905521","BP","GO:1905521","regulation of macrophage migration","8/173","51/21081",8.24449904800779e-09,4.88575682775245e-08,1.90271636254397e-08,"CYP19A1/MAPK3/MAPK1/PTK2/MIF/MIF/MAPK14/C5AR1",8
"GO:0070265","BP","GO:0070265","necrotic cell death","9/173","73/21081",8.47604733044658e-09,5.01597842716818e-08,1.9534300547518e-08,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TLR4",9
"GO:1902905","BP","GO:1902905","positive regulation of supramolecular fiber organization","14/173","234/21081",8.8224351731705e-09,5.21370334503497e-08,2.03043233910022e-08,"MTOR/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/RHOA/ABL1/NOX4/APP/MAPT/MAPT/MAPT/PSEN1",14
"GO:0031110","BP","GO:0031110","regulation of microtubule polymerization or depolymerization","10/173","99/21081",8.85850080695602e-09,5.22774582343835e-08,2.0359010626513e-08,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SNCA/ABL1/MAPT/MAPT/MAPT",10
"GO:0070304","BP","GO:0070304","positive regulation of stress-activated protein kinase signaling cascade","13/173","196/21081",8.92487017112142e-09,5.25960795521428e-08,2.04830949835797e-08,"HMGCR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRMT1/TLR4/XDH/APP",13
"GO:0044409","BP","GO:0044409","entry into host","13/173","197/21081",9.4879925560442e-09,5.57790221229559e-08,2.17226648443068e-08,"SRC/HTR2A/EGFR/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/CTSB/CTSB/CXCL8/CDK1/DPP4",13
"GO:0015918","BP","GO:0015918","sterol transport","11/173","129/21081",9.51748435847095e-09,5.57790221229559e-08,2.17226648443068e-08,"NPC1L1/CES1/CES1/NR1H3/SREBF2/PPARG/NR1H2/AKR1C1/SIRT1/CFTR/CETP",11
"GO:0051588","BP","GO:0051588","regulation of neurotransmitter transport","11/173","129/21081",9.51748435847095e-09,5.57790221229559e-08,2.17226648443068e-08,"BACE1/DRD2/CNR1/PRKCB/DRD3/GSK3B/HTR2A/CHRNA3/NOS1/LRRK2/SNCA",11
"GO:1901800","BP","GO:1901800","positive regulation of proteasomal protein catabolic process","11/173","129/21081",9.51748435847095e-09,5.57790221229559e-08,2.17226648443068e-08,"MDM2/GSK3B/AKT1/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/VCP/PSEN1",11
"GO:0003044","BP","GO:0003044","regulation of systemic arterial blood pressure mediated by a chemical signal","8/173","52/21081",9.67582295651475e-09,5.66288866972881e-08,2.20536373606513e-08,"CES1/CES1/AGTR1/DRD3/NOS3/ACE/RHOA/CTSG",8
"GO:0043297","BP","GO:0043297","apical junction assembly","10/173","100/21081",9.77367438976154e-09,5.70444264863967e-08,2.22154657904933e-08,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IKBKB/RHOA",10
"GO:1905954","BP","GO:1905954","positive regulation of lipid localization","10/173","100/21081",9.77367438976154e-09,5.70444264863967e-08,2.22154657904933e-08,"CYP19A1/CES1/CES1/NR1H3/SREBF2/NR1H2/MIF/MIF/SIRT1/CETP",10
"GO:0032729","BP","GO:0032729","positive regulation of interferon-gamma production","10/173","101/21081",1.07715465434184e-08,6.26963030999793e-08,2.44165409751316e-08,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TLR4/IL2",10
"GO:0090559","BP","GO:0090559","regulation of membrane permeability","10/173","101/21081",1.07715465434184e-08,6.26963030999793e-08,2.44165409751316e-08,"BCL2L1/MAPK8/GSK3B/MTOR/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/STAT3",10
"GO:0032370","BP","GO:0032370","positive regulation of lipid transport","9/173","75/21081",1.08127417564833e-08,6.27641253050514e-08,2.44429537549493e-08,"CYP19A1/CES1/CES1/NR1H3/NR1H2/MIF/MIF/SIRT1/CETP",9
"GO:0034394","BP","GO:0034394","protein localization to cell surface","9/173","75/21081",1.08127417564833e-08,6.27641253050514e-08,2.44429537549493e-08,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/AKT1",9
"GO:0090068","BP","GO:0090068","positive regulation of cell cycle process","16/173","323/21081",1.09584084540628e-08,6.35228888421733e-08,2.47384477486706e-08,"TERT/DRD2/MDM2/DRD3/CDK2/PRMT1/CHEK2/CDK4/AKT1/EGFR/CCND1/INSR/RHOA/CDK1/APP/EP300",16
"GO:0055123","BP","GO:0055123","digestive system development","12/173","164/21081",1.13043229326521e-08,6.53331069768587e-08,2.54434217754325e-08,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SRC/EGFR/INSR/CXCL8",12
"GO:0002701","BP","GO:0002701","negative regulation of production of molecular mediator of immune response","8/173","53/21081",1.13168196599125e-08,6.53331069768587e-08,2.54434217754325e-08,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0030574","BP","GO:0030574","collagen catabolic process","8/173","53/21081",1.13168196599125e-08,6.53331069768587e-08,2.54434217754325e-08,"CTSD/MMP3/CTSB/CTSB/MMP9/MMP2/MMP13/MMP12",8
"GO:0043255","BP","GO:0043255","regulation of carbohydrate biosynthetic process","10/173","102/21081",1.18585254295678e-08,6.82935279278557e-08,2.65963324875424e-08,"PPARA/GSK3B/MTOR/AKT1/INSR/SNCA/PPP1CA/SIRT1/OGT/EP300",10
"GO:0006470","BP","GO:0006470","protein dephosphorylation","17/173","371/21081",1.18617612640051e-08,6.82935279278557e-08,2.65963324875424e-08,"PTPN11/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/ACP1/GSK3B/IKBKB/MTOR/LRRK2/PPP1CA/PPP2CA",17
"GO:0051701","BP","GO:0051701","interaction with host","15/173","281/21081",1.18962479685007e-08,6.8399401377753e-08,2.66375640004033e-08,"BCL2L1/SRC/HTR2A/EGFR/INSR/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/CTSB/CTSB/CXCL8/CDK1/DPP4",15
"GO:0051348","BP","GO:0051348","negative regulation of transferase activity","16/173","325/21081",1.19541974034919e-08,6.86397091451853e-08,2.67311498126448e-08,"FABP4/HMGCR/IGF1R/PPARG/SRC/GSK3B/CSK/AKT1/SNCA/SIRT1/ABL1/MAPT/MAPT/MAPT/PPP2CA/PSEN1",16
"GO:0002718","BP","GO:0002718","regulation of cytokine production involved in immune response","12/173","165/21081",1.21049674336263e-08,6.94116148791878e-08,2.70317619229498e-08,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/TLR4/MIF/MIF",12
"GO:0010039","BP","GO:0010039","response to iron ion","7/173","35/21081",1.22959862145406e-08,7.0411921058737e-08,2.74213226404565e-08,"G6PD/SLC6A3/SLC6A3/DRD2/MDM2/CCND1/SNCA",7
"GO:0034329","BP","GO:0034329","cell junction assembly","19/173","471/21081",1.23957146587673e-08,7.08874718507433e-08,2.76065218439926e-08,"NR1H4/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/SRC/PRKCA/IKBKB/PTK2/SNCA/ACE/RHOA/ABL1/APP",19
"GO:0051480","BP","GO:0051480","regulation of cytosolic calcium ion concentration","17/173","373/21081",1.28405263683168e-08,7.33325222298092e-08,2.85587258785993e-08,"ESR1/DRD2/CNR1/CXCR3/AGTR1/DRD3/TACR1/HTR2A/PIK3CG/NOS1/SNCA/F2/GLP1R/ABL1/CD38/IL2/C5AR1",17
"GO:0043537","BP","GO:0043537","negative regulation of blood vessel endothelial cell migration","10/173","103/21081",1.30414330450159e-08,7.41807884983566e-08,2.88890759483759e-08,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/RHOA",10
"GO:0060191","BP","GO:0060191","regulation of lipase activity","10/173","103/21081",1.30414330450159e-08,7.41807884983566e-08,2.88890759483759e-08,"ESR1/NR1H3/AGTR1/NR1H2/HTR2A/EGFR/SNCA/RHOA/ABL1/C5AR1",10
"GO:0070301","BP","GO:0070301","cellular response to hydrogen peroxide","10/173","103/21081",1.30414330450159e-08,7.41807884983566e-08,2.88890759483759e-08,"FABP1/MDM2/IL6/SRC/NQO1/LRRK2/SIRT1/ABL1/CYP1B1/CDK1",10
"GO:0031279","BP","GO:0031279","regulation of cyclase activity","8/173","54/21081",1.31926974272559e-08,7.48408162462089e-08,2.91461181303441e-08,"MAPK3/NOS2/MAPK8/DRD2/DRD3/NOS3/NOS1/MAPK14",8
"GO:0050850","BP","GO:0050850","positive regulation of calcium-mediated signaling","8/173","54/21081",1.31926974272559e-08,7.48408162462089e-08,2.91461181303441e-08,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0002221","BP","GO:0002221","pattern recognition receptor signaling pathway","14/173","242/21081",1.35261293996022e-08,7.66300317585463e-08,2.98429128648065e-08,"NR1H4/ESR1/NR1H3/XIAP/IKBKB/CHUK/TLR4/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/CTSB/CTSB",14
"GO:0002712","BP","GO:0002712","regulation of B cell mediated immunity","9/173","77/21081",1.36950498494426e-08,7.73806739498426e-08,3.01352440696021e-08,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL2",9
"GO:0002889","BP","GO:0002889","regulation of immunoglobulin mediated immune response","9/173","77/21081",1.36950498494426e-08,7.73806739498426e-08,3.01352440696021e-08,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL2",9
"GO:0045446","BP","GO:0045446","endothelial cell differentiation","11/173","134/21081",1.41953856801507e-08,8.01011869255781e-08,3.11947246651246e-08,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IKBKB/XDH/FASN",11
"GO:0035265","BP","GO:0035265","organ growth","13/173","204/21081",1.44188777326865e-08,8.1254391891492e-08,3.16438305120525e-08,"CYP19A1/G6PD/PPARA/PTPN11/ESR1/MTOR/MAPK1/PIM1/AKT1/PTK2/MAPK14/MMP13/CDK1",13
"GO:0071715","BP","GO:0071715","icosanoid transport","8/173","55/21081",1.53310487739493e-08,8.61661722758077e-08,3.355668152694e-08,"NOS2/DRD2/DRD3/MIF/MIF/ACE/ABCC1/ABCC1",8
"GO:1901571","BP","GO:1901571","fatty acid derivative transport","8/173","55/21081",1.53310487739493e-08,8.61661722758077e-08,3.355668152694e-08,"NOS2/DRD2/DRD3/MIF/MIF/ACE/ABCC1/ABCC1",8
"GO:0002064","BP","GO:0002064","epithelial cell development","14/173","246/21081",1.66456676899909e-08,9.34312311952067e-08,3.63859968138299e-08,"ESR1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SRC/GSK3B/IKBKB/AKR1B1/FASN",14
"GO:0042310","BP","GO:0042310","vasoconstriction","9/173","79/21081",1.72284332887647e-08,9.65746873930887e-08,3.76101890431025e-08,"PTGS2/AGTR1/HTR1A/HTR2A/AKT1/EGFR/ACE/RHOA/CD38",9
"GO:0006352","BP","GO:0006352","DNA-templated transcription, initiation","15/173","290/21081",1.81266905013287e-08,1.01476031541694e-07,3.9518975754925e-08,"NR1H4/PPARA/NR1I3/NR1I2/MAPK3/ESR1/ESR2/RORA/NR1H3/PPARG/NR1H2/CDK4/CCND1/ESRRA/CDK1",15
"GO:0046328","BP","GO:0046328","regulation of JNK cascade","13/173","208/21081",1.8179728526652e-08,1.01639034881243e-07,3.95824560164778e-08,"IGF1R/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/AKT1/TLR4/EGFR/APP",13
"GO:0070431","BP","GO:0070431","nucleotide-binding oligomerization domain containing 2 signaling pathway","6/173","22/21081",1.87357493936115e-08,1.04609985773266e-07,4.07394675243894e-08,"TLR4/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",6
"GO:1903364","BP","GO:1903364","positive regulation of cellular protein catabolic process","12/173","172/21081",1.92927069878584e-08,1.07578362193452e-07,4.18954764261823e-08,"MDM2/GSK3B/AKT1/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/PTK2/VCP/PSEN1",12
"GO:0035304","BP","GO:0035304","regulation of protein dephosphorylation","12/173","173/21081",2.05844891384425e-08,1.14631054192978e-07,4.46420872258145e-08,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/GSK3B/IKBKB/MTOR",12
"GO:1903321","BP","GO:1903321","negative regulation of protein modification by small protein conjugation or removal","10/173","108/21081",2.06653914223404e-08,1.14930953080529e-07,4.47588802919801e-08,"MTOR/AKT1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/ABL1/OGT/PSEN1",10
"GO:1903362","BP","GO:1903362","regulation of cellular protein catabolic process","15/173","294/21081",2.17504561903046e-08,1.20807435755038e-07,4.70474263930634e-08,"MDM2/GSK3B/CSNK2A1/CSNK2A2/AKT1/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/PTK2/OGT/VCP/PSEN1",15
"GO:0016525","BP","GO:0016525","negative regulation of angiogenesis","13/173","212/21081",2.28048265279643e-08,1.2649831320799e-07,4.92636901222481e-08,"ALOX5/ALOX5/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/RHOA",13
"GO:0006692","BP","GO:0006692","prostanoid metabolic process","8/173","58/21081",2.36361444961317e-08,1.30768200474041e-07,5.09265613321259e-08,"FABP5/PTGS1/PTGS2/MIF/MIF/AKR1C1/CBR1/SIRT1",8
"GO:0006693","BP","GO:0006693","prostaglandin metabolic process","8/173","58/21081",2.36361444961317e-08,1.30768200474041e-07,5.09265613321259e-08,"FABP5/PTGS1/PTGS2/MIF/MIF/AKR1C1/CBR1/SIRT1",8
"GO:0031100","BP","GO:0031100","animal organ regeneration","9/173","82/21081",2.40205606193553e-08,1.32722187349338e-07,5.16875248697919e-08,"PPARG/IL6/CSNK2A2/CDK4/CCNA2/EGFR/CCND1/CDK1/C5AR1",9
"GO:0031281","BP","GO:0031281","positive regulation of cyclase activity","6/173","23/21081",2.51764815121133e-08,1.38748210045356e-07,5.40343080579453e-08,"MAPK3/NOS2/MAPK8/NOS3/NOS1/MAPK14",6
"GO:0071157","BP","GO:0071157","negative regulation of cell cycle arrest","6/173","23/21081",2.51764815121133e-08,1.38748210045356e-07,5.40343080579453e-08,"MDM2/CHEK2/CDK4/CCND1/MIF/MIF",6
"GO:0003012","BP","GO:0003012","muscle system process","19/173","494/21081",2.65339188986085e-08,1.46039665026149e-07,5.6873903066011e-08,"G6PD/PPARA/DRD2/PTGS2/TACR1/PRKCA/HTR2A/MTOR/PIK3CA/PIK3CG/NOS3/CHUK/PARP1/CHRNA3/NOS1/HDAC4/PTK2/RHOA/CD38",19
"GO:0019233","BP","GO:0019233","sensory perception of pain","10/173","111/21081",2.69309537294153e-08,1.48033146696359e-07,5.76502475150008e-08,"FABP5/MAPK3/BACE1/CNR1/PTGS2/HTR2A/MTOR/MAPK1/MC1R/MGLL",10
"GO:0010742","BP","GO:0010742","macrophage derived foam cell differentiation","7/173","39/21081",2.73586779358177e-08,1.49996158128115e-07,5.84147255892773e-08,"PPARA/NR1H3/PPARG/AGTR1/NR1H2/CETP/EP300",7
"GO:0090077","BP","GO:0090077","foam cell differentiation","7/173","39/21081",2.73586779358177e-08,1.49996158128115e-07,5.84147255892773e-08,"PPARA/NR1H3/PPARG/AGTR1/NR1H2/CETP/EP300",7
"GO:1900180","BP","GO:1900180","regulation of protein localization to nucleus","11/173","143/21081",2.79833386631565e-08,1.53223203582155e-07,5.96714709420538e-08,"TERT/PTGS2/SRC/GSK3B/MAPK1/AKT1/PARP1/F2/MAPK14/CDK1/PSEN1",11
"GO:0042770","BP","GO:0042770","signal transduction in response to DNA damage","11/173","144/21081",3.00844845533505e-08,1.64516055170124e-07,6.40693757608439e-08,"MDM2/CDK2/PRMT1/CHEK2/MIF/MIF/SIRT1/ABL1/MAPK14/CDK1/EP300",11
"GO:0019229","BP","GO:0019229","regulation of vasoconstriction","8/173","60/21081",3.11139126341353e-08,1.69926754219076e-07,6.61765263981338e-08,"PTGS2/AGTR1/HTR2A/AKT1/EGFR/ACE/RHOA/CD38",8
"GO:0001649","BP","GO:0001649","osteoblast differentiation","14/173","259/21081",3.18253002819e-08,1.73588832988181e-07,6.76026917683221e-08,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/AKT1/HDAC4/PTK2/ESRRA/FASN",14
"GO:0006641","BP","GO:0006641","triglyceride metabolic process","10/173","113/21081",3.19884225778281e-08,1.7425488145281e-07,6.78620786671333e-08,"FABP4/FABP5/FABP1/PTPN11/NR1H3/NR1H2/PIK3CG/SIRT1/MGLL/CETP",10
"GO:0034504","BP","GO:0034504","protein localization to nucleus","15/173","303/21081",3.24321872418512e-08,1.76446048131403e-07,6.87154098580633e-08,"TERT/MDM2/PTGS2/SRC/GSK3B/MAPK1/AKT1/PARP1/LRRK2/F2/STAT3/MAPK14/CDK1/MMP12/PSEN1",15
"GO:0045766","BP","GO:0045766","positive regulation of angiogenesis","13/173","219/21081",3.35132147332045e-08,1.82094180820186e-07,7.09150270030925e-08,"SERPINE1/TERT/PTGS2/AGTR1/PRKCB/PRKCA/NOS3/CXCL8/SIRT1/ABL1/STAT3/CYP1B1/C5AR1",13
"GO:0043271","BP","GO:0043271","negative regulation of ion transport","12/173","181/21081",3.40565569443854e-08,1.84810102754398e-07,7.19727196566161e-08,"DRD2/CNR1/PTGS2/DRD3/HTR2A/MTOR/NOS3/AKT1/NOS1/SNCA/MMP9/MAOB",12
"GO:0097529","BP","GO:0097529","myeloid leukocyte migration","14/173","261/21081",3.50429502259513e-08,1.8992027488529e-07,7.39628326466105e-08,"CYP19A1/MAPK3/SERPINE1/IL6/PIK3CG/MAPK1/PTK2/MIF/MIF/CXCL8/STAT5B/MAPK14/DPP4/C5AR1",14
"GO:0050920","BP","GO:0050920","regulation of chemotaxis","14/173","262/21081",3.67598245379092e-08,1.98971330524301e-07,7.74876891365648e-08,"CYP19A1/MAPK3/SERPINE1/IL6/MAPK1/PTK2/MIF/MIF/CXCL8/MAPK14/DPP4/C5AR1/ELANE/ELANE",14
"GO:0050777","BP","GO:0050777","negative regulation of immune response","14/173","263/21081",3.85525380791735e-08,2.08409331168458e-07,8.11632380614178e-08,"NR1H3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/PPARG/NR1H2/MMP12/IL2",14
"GO:1903320","BP","GO:1903320","regulation of protein modification by small protein conjugation or removal","14/173","264/21081",4.04240686699861e-08,2.18248879007333e-07,8.49951661194651e-08,"XIAP/MTOR/AKT1/LRRK2/HDAC4/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/ABL1/OGT/VCP/PSEN1",14
"GO:0030168","BP","GO:0030168","platelet activation","12/173","184/21081",4.08646919717552e-08,2.20347812421305e-07,8.5812577851455e-08,"MAPK3/PTPN11/IL6/PRKCB/SRC/PRKCA/PIK3CA/PIK3CG/MAPK1/NOS3/TLR4/F2",12
"GO:0030301","BP","GO:0030301","cholesterol transport","10/173","116/21081",4.11479843062443e-08,2.21594151225896e-07,8.6297953878215e-08,"NPC1L1/CES1/CES1/NR1H3/SREBF2/NR1H2/AKR1C1/SIRT1/CFTR/CETP",10
"GO:0010286","BP","GO:0010286","heat acclimation","5/173","13/21081",4.28638580274305e-08,2.29381023625381e-07,8.93304849782855e-08,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",5
"GO:0010745","BP","GO:0010745","negative regulation of macrophage derived foam cell differentiation","5/173","13/21081",4.28638580274305e-08,2.29381023625381e-07,8.93304849782855e-08,"PPARA/NR1H3/PPARG/NR1H2/CETP",5
"GO:0060700","BP","GO:0060700","regulation of ribonuclease activity","5/173","13/21081",4.28638580274305e-08,2.29381023625381e-07,8.93304849782855e-08,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",5
"GO:0070370","BP","GO:0070370","cellular heat acclimation","5/173","13/21081",4.28638580274305e-08,2.29381023625381e-07,8.93304849782855e-08,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",5
"GO:0090063","BP","GO:0090063","positive regulation of microtubule nucleation","5/173","13/21081",4.28638580274305e-08,2.29381023625381e-07,8.93304849782855e-08,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",5
"GO:0048754","BP","GO:0048754","branching morphogenesis of an epithelial tube","12/173","185/21081",4.33911124487612e-08,2.31910486534323e-07,9.03155627533302e-08,"ESR1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SRC/PPP1CA/ABL1",12
"GO:0071156","BP","GO:0071156","regulation of cell cycle arrest","10/173","117/21081",4.46778206399609e-08,2.38487512436173e-07,9.28769294446158e-08,"MDM2/CDK2/PRMT1/CHEK2/CDK4/CCND1/MIF/MIF/CDK1/EP300",10
"GO:0032886","BP","GO:0032886","regulation of microtubule-based process","14/173","267/21081",4.65428872203029e-08,2.4813140250824e-07,9.66326602526793e-08,"TACR1/GSK3B/ERBB2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SNCA/RHOA/ABL1/MAPT/MAPT/MAPT",14
"GO:0046902","BP","GO:0046902","regulation of mitochondrial membrane permeability","9/173","89/21081",4.96047261518872e-08,2.64123410299961e-07,1.02860611411115e-07,"BCL2L1/MAPK8/GSK3B/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/STAT3",9
"GO:0052126","BP","GO:0052126","movement in host environment","13/173","227/21081",5.11487405867569e-08,2.72003753132829e-07,1.05929543774958e-07,"SRC/HTR2A/EGFR/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/CTSB/CTSB/CXCL8/CDK1/DPP4",13
"GO:0006096","BP","GO:0006096","glycolytic process","10/173","119/21081",5.25476831720914e-08,2.79093882247771e-07,1.08690734140168e-07,"PPARA/HTR2A/HDAC4/INSR/STAT3/APP/PFKFB3/OGT/EP300/PSEN1",10
"GO:0048565","BP","GO:0048565","digestive tract development","11/173","152/21081",5.26332958532816e-08,2.79199593109355e-07,1.08731902334396e-07,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SRC/EGFR/CXCL8",11
"GO:0051099","BP","GO:0051099","positive regulation of binding","12/173","189/21081",5.49553125394166e-08,2.91153519925163e-07,1.13387257267309e-07,"TERT/PPARG/GSK3B/PARP1/LRRK2/ACE/MMP9/ABL1/APP/PPP2CA/EP300/PSEN1",12
"GO:0071276","BP","GO:0071276","cellular response to cadmium ion","7/173","43/21081",5.57579820980921e-08,2.95038189208958e-07,1.14900108616636e-07,"MAPK3/MAPK8/MAPK1/CHUK/AKT1/EGFR/MMP9",7
"GO:0002700","BP","GO:0002700","regulation of production of molecular mediator of immune response","13/173","229/21081",5.6697137109272e-08,2.99634496986688e-07,1.16690101513191e-07,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/TLR4/MIF/MIF/IL2",13
"GO:0006757","BP","GO:0006757","ATP generation from ADP","10/173","120/21081",5.69224626165953e-08,3.00451607028464e-07,1.1700831805595e-07,"PPARA/HTR2A/HDAC4/INSR/STAT3/APP/PFKFB3/OGT/EP300/PSEN1",10
"GO:0050886","BP","GO:0050886","endocrine process","9/173","91/21081",6.0314018339219e-08,3.17564143647263e-07,1.23672649617495e-07,"PTPN11/CES1/CES1/AGTR1/DRD3/NOS3/ACE/RHOA/CTSG",9
"GO:0070830","BP","GO:0070830","bicellular tight junction assembly","9/173","91/21081",6.0314018339219e-08,3.17564143647263e-07,1.23672649617495e-07,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IKBKB",9
"GO:0050680","BP","GO:0050680","negative regulation of epithelial cell proliferation","12/173","191/21081",6.17131486701513e-08,3.24528674133011e-07,1.26384926666855e-07,"ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/XDH",12
"GO:0032649","BP","GO:0032649","regulation of interferon-gamma production","11/173","155/21081",6.43599088027799e-08,3.37611422843225e-07,1.31479891667278e-07,"NR1H4/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TLR4/IL2",11
"GO:0050830","BP","GO:0050830","defense response to Gram-positive bacterium","11/173","155/21081",6.43599088027799e-08,3.37611422843225e-07,1.31479891667278e-07,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/CTSG/C5AR1",11
"GO:0051583","BP","GO:0051583","dopamine uptake involved in synaptic transmission","5/173","14/21081",6.62347380178981e-08,3.46590396352277e-07,1.34976676385968e-07,"SLC6A3/SLC6A3/DRD2/DRD3/SNCA",5
"GO:0051934","BP","GO:0051934","catecholamine uptake involved in synaptic transmission","5/173","14/21081",6.62347380178981e-08,3.46590396352277e-07,1.34976676385968e-07,"SLC6A3/SLC6A3/DRD2/DRD3/SNCA",5
"GO:0050766","BP","GO:0050766","positive regulation of phagocytosis","9/173","92/21081",6.63870316900637e-08,3.46960021711046e-07,1.35120623832175e-07,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG",9
"GO:0010596","BP","GO:0010596","negative regulation of endothelial cell migration","10/173","122/21081",6.66455554414919e-08,3.47883249472849e-07,1.35480167016715e-07,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/RHOA",10
"GO:1905517","BP","GO:1905517","macrophage migration","8/173","66/21081",6.69852615677275e-08,3.49227455707085e-07,1.36003656679971e-07,"CYP19A1/MAPK3/MAPK1/PTK2/MIF/MIF/MAPK14/C5AR1",8
"GO:1990000","BP","GO:1990000","amyloid fibril formation","6/173","27/21081",7.18441347723765e-08,3.74100157656652e-07,1.45690118501259e-07,"MDM2/APP/MAPT/MAPT/MAPT/PSEN1",6
"GO:0050764","BP","GO:0050764","regulation of phagocytosis","10/173","123/21081",7.20343472517805e-08,3.74631507310668e-07,1.45897048096114e-07,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/CSK",10
"GO:0120192","BP","GO:0120192","tight junction assembly","9/173","93/21081",7.2986455809548e-08,3.79119132927591e-07,1.4764471565128e-07,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IKBKB",9
"GO:1902107","BP","GO:1902107","positive regulation of leukocyte differentiation","12/173","194/21081",7.32481732456343e-08,3.80014027009402e-07,1.47993224525592e-07,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRKCA/RHOA/STAT5B/IL2",12
"GO:0090257","BP","GO:0090257","regulation of muscle system process","14/173","277/21081",7.34801357078911e-08,3.80752556857109e-07,1.48280838681393e-07,"G6PD/PPARA/PTGS2/TACR1/PRKCA/MTOR/PIK3CG/NOS3/PARP1/CHRNA3/NOS1/HDAC4/PTK2/RHOA",14
"GO:0042391","BP","GO:0042391","regulation of membrane potential","18/173","473/21081",7.40226032537667e-08,3.83096274330395e-07,1.49193579479353e-07,"BCL2L1/DRD2/CNR1/SRC/GSK3B/AKT1/PARP1/CHRNA3/LRRK2/ABL1/APP/CFTR/MAPT/MAPT/MAPT/VCP/CACNA1B/PSEN1",18
"GO:0002821","BP","GO:0002821","positive regulation of adaptive immune response","11/173","158/21081",7.8353218834059e-08,4.05015604411091e-07,1.57729875793496e-07,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/SIRT1/IL2",11
"GO:0001942","BP","GO:0001942","hair follicle development","9/173","94/21081",8.01505809294291e-08,4.13802938480127e-07,1.61152028165329e-07,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/EGFR",9
"GO:0031669","BP","GO:0031669","cellular response to nutrient levels","13/173","236/21081",8.06446879059299e-08,4.1584863945667e-07,1.61948708978183e-07,"NR1H4/PPARA/SRD5A1/MAPK3/SREBF2/MAPK8/MDM2/PPARG/MTOR/MAPK1/PIM1/LRRK2/SIRT1",13
"GO:0030307","BP","GO:0030307","positive regulation of cell growth","12/173","196/21081",8.19733857556666e-08,4.22187777061609e-07,1.64417432099404e-07,"ERBB2/CSNK2A1/MTOR/AKT1/EGFR/F2/RHOA/CD38/MAPT/MAPT/MAPT/IL2",12
"GO:0007173","BP","GO:0007173","epidermal growth factor receptor signaling pathway","10/173","125/21081",8.39754582325449e-08,4.31975450399617e-07,1.68229158075138e-07,"PTPN11/SRC/PIK3CA/AKT1/EGFR/PTK2/MMP9/ABL1/APP/PSEN1",10
"GO:0001890","BP","GO:0001890","placenta development","11/173","160/21081",8.91233922631165e-08,4.57902410793207e-07,1.78326191863577e-07,"PLG/MAPK3/PPARG/PTGS2/MAPK1/AKT1/EGFR/PTK2/CTSB/CTSB/MAPK14",11
"GO:0070423","BP","GO:0070423","nucleotide-binding oligomerization domain containing signaling pathway","7/173","46/21081",9.0717856158847e-08,4.65484772919837e-07,1.81279078180621e-07,"XIAP/TLR4/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",7
"GO:1903579","BP","GO:1903579","negative regulation of ATP metabolic process","6/173","28/21081",9.08182811839362e-08,4.65484772919837e-07,1.81279078180621e-07,"PPARA/PARP1/HDAC4/SNCA/RHOA/STAT3",6
"GO:0030879","BP","GO:0030879","mammary gland development","11/173","161/21081",9.49859268649631e-08,4.86259281023167e-07,1.8936953333129e-07,"CYP19A1/ESR1/SLC6A3/SLC6A3/SRC/MAPK1/AKT1/XDH/CCND1/STAT5B/FASN",11
"GO:0090181","BP","GO:0090181","regulation of cholesterol metabolic process","8/173","69/21081",9.55004305628572e-08,4.88304848930903e-07,1.90166162321631e-07,"NR1H4/HMGCR/CES1/CES1/SREBF2/FASN/ACACA/ACACA",8
"GO:0022404","BP","GO:0022404","molting cycle process","9/173","96/21081",9.63374358577437e-08,4.9081266781721e-07,1.911428110165e-07,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/EGFR",9
"GO:0022405","BP","GO:0022405","hair cycle process","9/173","96/21081",9.63374358577437e-08,4.9081266781721e-07,1.911428110165e-07,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/EGFR",9
"GO:0120193","BP","GO:0120193","tight junction organization","9/173","96/21081",9.63374358577437e-08,4.9081266781721e-07,1.911428110165e-07,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IKBKB",9
"GO:0010968","BP","GO:0010968","regulation of microtubule nucleation","5/173","15/21081",9.86930486121495e-08,5.02211692877872e-07,1.95582064189473e-07,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",5
"GO:0001894","BP","GO:0001894","tissue homeostasis","14/173","285/21081",1.04424523793172e-07,5.30741389470323e-07,2.06692711411316e-07,"PTPN11/PTGS2/IL6/SRC/PRKCA/CSK/NOS3/TLR4/EGFR/AKR1B1/NOX4/CD38/ACACA/ACACA",14
"GO:0046031","BP","GO:0046031","ADP metabolic process","10/173","128/21081",1.05156697869102e-07,5.33824144857606e-07,2.07893264227163e-07,"PPARA/HTR2A/HDAC4/INSR/STAT3/APP/PFKFB3/OGT/EP300/PSEN1",10
"GO:0003073","BP","GO:0003073","regulation of systemic arterial blood pressure","9/173","97/21081",1.05448388701768e-07,5.34666114073761e-07,2.08221161963546e-07,"CES1/CES1/DRD2/AGTR1/DRD3/NOS3/ACE/RHOA/CTSG",9
"GO:0035872","BP","GO:0035872","nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway","7/173","47/21081",1.05860831860065e-07,5.35479374492165e-07,2.08537879303287e-07,"XIAP/TLR4/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",7
"GO:0070849","BP","GO:0070849","response to epidermal growth factor","7/173","47/21081",1.05860831860065e-07,5.35479374492165e-07,2.08537879303287e-07,"MAPK3/PTPN11/ERBB2/MAPK1/AKT1/EGFR/STAT5B",7
"GO:0045071","BP","GO:0045071","negative regulation of viral genome replication","8/173","70/21081",1.0707484419039e-07,5.40976234203288e-07,2.10678584476241e-07,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:2000045","BP","GO:2000045","regulation of G1/S transition of mitotic cell cycle","12/173","202/21081",1.13998388037581e-07,5.75272150560192e-07,2.24034836848453e-07,"TERT/MDM2/CDK2/PRMT1/CHEK2/CDK4/WEE1/AKT1/EGFR/CCND1/CDK1/EP300",12
"GO:0098773","BP","GO:0098773","skin epidermis development","9/173","98/21081",1.15300696563199e-07,5.81153807469787e-07,2.26325398011298e-07,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/EGFR",9
"GO:0006805","BP","GO:0006805","xenobiotic metabolic process","10/173","130/21081",1.2176606943738e-07,6.11565046145894e-07,2.38168795764043e-07,"NR1I2/PTGS1/CES1/CES1/RORA/NQO1/CYP26A1/AKR1C1/EPHX1/CYP1B1",10
"GO:0010923","BP","GO:0010923","negative regulation of phosphatase activity","10/173","130/21081",1.2176606943738e-07,6.11565046145894e-07,2.38168795764043e-07,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GSK3B/IKBKB",10
"GO:0035270","BP","GO:0035270","endocrine system development","10/173","130/21081",1.2176606943738e-07,6.11565046145894e-07,2.38168795764043e-07,"SRD5A1/MAPK3/SLC6A3/SLC6A3/DRD2/IL6/GSK3B/MAPK1/AKT1/INSR",10
"GO:0045776","BP","GO:0045776","negative regulation of blood pressure","7/173","48/21081",1.230828556634e-07,6.17448705683337e-07,2.40460136833238e-07,"PPARA/NOS2/DRD2/CNR1/DRD3/NOS3/NOS1",7
"GO:0016485","BP","GO:0016485","protein processing","13/173","246/21081",1.30665765035176e-07,6.53944447154844e-07,2.54673092350501e-07,"CES1/CES1/SERPINE1/MDM2/XIAP/SRC/PARP1/LRRK2/ACE/CTSG/PSEN2/OGT/PSEN1",13
"GO:1904018","BP","GO:1904018","positive regulation of vasculature development","13/173","246/21081",1.30665765035176e-07,6.53944447154844e-07,2.54673092350501e-07,"SERPINE1/TERT/PTGS2/AGTR1/PRKCB/PRKCA/NOS3/CXCL8/SIRT1/ABL1/STAT3/CYP1B1/C5AR1",13
"GO:0035303","BP","GO:0035303","regulation of dephosphorylation","13/173","247/21081",1.36951570204393e-07,6.84596731527607e-07,2.66610363295735e-07,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/SRC/GSK3B/IKBKB/MTOR",13
"GO:0030279","BP","GO:0030279","negative regulation of ossification","9/173","100/21081",1.3743437960851e-07,6.86202912992432e-07,2.6723587698012e-07,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/HDAC4",9
"GO:0007613","BP","GO:0007613","memory","10/173","132/21081",1.40640727961882e-07,7.01387855762952e-07,2.73149523543462e-07,"DRD2/CNR1/PTGS2/HTR2A/MTOR/INSR/MAPT/MAPT/MAPT/PSEN1",10
"GO:0010921","BP","GO:0010921","regulation of phosphatase activity","12/173","206/21081",1.41143797015311e-07,7.03071504710502e-07,2.73805206278854e-07,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DRD2/GSK3B/IKBKB/MTOR",12
"GO:1901029","BP","GO:1901029","negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway","5/173","16/21081",1.42601399949419e-07,7.09500407945062e-07,2.76308887859592e-07,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",5
"GO:0002699","BP","GO:0002699","positive regulation of immune effector process","15/173","340/21081",1.46075547206463e-07,7.25935672608493e-07,2.82709461629498e-07,"NOS2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/TLR4/MIF/MIF/STAT5B/IL2",15
"GO:0031647","BP","GO:0031647","regulation of protein stability","15/173","342/21081",1.57557331791272e-07,7.82080727548029e-07,3.0457467483507e-07,"TERT/MDM2/SRC/CHEK2/MAPK1/PIM1/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SNCA/SIRT1/EP300",15
"GO:0031330","BP","GO:0031330","negative regulation of cellular catabolic process","14/173","295/21081",1.59427299790981e-07,7.90439436186557e-07,3.07829902685528e-07,"CNR1/CSNK2A1/CSNK2A2/MTOR/PIK3CA/PIK3CG/AKT1/LRRK2/PTK2/SNCA/STAT3/MAPK14/OGT/PSEN1",14
"GO:0010874","BP","GO:0010874","regulation of cholesterol efflux","7/173","50/21081",1.64685869118845e-07,8.15559741125844e-07,3.17612791381211e-07,"CES1/CES1/NR1H3/SREBF2/NR1H2/SIRT1/CETP",7
"GO:0070059","BP","GO:0070059","intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress","8/173","74/21081",1.66249266552509e-07,8.22343578092681e-07,3.20254698879413e-07,"BCL2L1/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SIRT1",8
"GO:0007050","BP","GO:0007050","cell cycle arrest","13/173","252/21081",1.72643348366613e-07,8.52978589778765e-07,3.32185243124009e-07,"MDM2/CDK2/PRMT1/CHEK2/MTOR/CDK4/CCND1/MIF/MIF/CXCL8/ABL1/CDK1/EP300",13
"GO:0031109","BP","GO:0031109","microtubule polymerization or depolymerization","10/173","135/21081",1.73776985581786e-07,8.55243603485804e-07,3.33067333410879e-07,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SNCA/ABL1/MAPT/MAPT/MAPT",10
"GO:0043244","BP","GO:0043244","regulation of protein-containing complex disassembly","10/173","135/21081",1.73776985581786e-07,8.55243603485804e-07,3.33067333410879e-07,"IGF1R/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/INSR",10
"GO:0032373","BP","GO:0032373","positive regulation of sterol transport","6/173","31/21081",1.73906913017589e-07,8.55243603485804e-07,3.33067333410879e-07,"CES1/CES1/NR1H3/NR1H2/SIRT1/CETP",6
"GO:0032376","BP","GO:0032376","positive regulation of cholesterol transport","6/173","31/21081",1.73906913017589e-07,8.55243603485804e-07,3.33067333410879e-07,"CES1/CES1/NR1H3/NR1H2/SIRT1/CETP",6
"GO:0007569","BP","GO:0007569","cell aging","11/173","171/21081",1.75357505682831e-07,8.61380394966879e-07,3.35457254558455e-07,"SERPINE1/TERT/CHEK2/MTOR/MIF/MIF/SIRT1/ABL1/MAPK14/NOX4/CDK1",11
"GO:0032371","BP","GO:0032371","regulation of sterol transport","8/173","75/21081",1.84808851602781e-07,9.05712584152498e-07,3.52722047859615e-07,"CES1/CES1/NR1H3/SREBF2/PPARG/NR1H2/SIRT1/CETP",8
"GO:1900076","BP","GO:1900076","regulation of cellular response to insulin stimulus","8/173","75/21081",1.84808851602781e-07,9.05712584152498e-07,3.52722047859615e-07,"NR1H4/PTPN11/PRKCB/SRC/CDK4/SIRT1/ESRRA/OGT",8
"GO:0032609","BP","GO:0032609","interferon-gamma production","11/173","172/21081",1.86020318016029e-07,9.09642700002717e-07,3.54252597986962e-07,"NR1H4/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TLR4/IL2",11
"GO:0006165","BP","GO:0006165","nucleoside diphosphate phosphorylation","10/173","136/21081",1.86253035773679e-07,9.09642700002717e-07,3.54252597986962e-07,"PPARA/HTR2A/HDAC4/INSR/STAT3/APP/PFKFB3/OGT/EP300/PSEN1",10
"GO:0071466","BP","GO:0071466","cellular response to xenobiotic stimulus","10/173","136/21081",1.86253035773679e-07,9.09642700002717e-07,3.54252597986962e-07,"NR1I2/PTGS1/CES1/CES1/RORA/NQO1/CYP26A1/AKR1C1/EPHX1/CYP1B1",10
"GO:0006959","BP","GO:0006959","humoral immune response","17/173","451/21081",1.9910582818862e-07,9.71298121668712e-07,3.7826377655751e-07,"ALOX5/ALOX5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/F2/CXCL8/CTSG/C5AR1/ELANE/ELANE",17
"GO:0060134","BP","GO:0060134","prepulse inhibition","5/173","17/21081",2.0067895785083e-07,9.76729543995618e-07,3.80378997698805e-07,"SLC6A3/SLC6A3/BACE1/DRD2/DRD3",5
"GO:0097201","BP","GO:0097201","negative regulation of transcription from RNA polymerase II promoter in response to stress","5/173","17/21081",2.0067895785083e-07,9.76729543995618e-07,3.80378997698805e-07,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",5
"GO:0002440","BP","GO:0002440","production of molecular mediator of immune response","16/173","399/21081",2.023313672693e-07,9.83645285500293e-07,3.83072274295242e-07,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/TLR4/MIF/MIF/SIRT1/IL2/ELANE/ELANE",16
"GO:0046939","BP","GO:0046939","nucleotide phosphorylation","10/173","138/21081",2.13587104218965e-07,1.03717897808729e-06,4.03920514685368e-07,"PPARA/HTR2A/HDAC4/INSR/STAT3/APP/PFKFB3/OGT/EP300/PSEN1",10
"GO:0034764","BP","GO:0034764","positive regulation of transmembrane transport","12/173","215/21081",2.24341812062475e-07,1.08691945205639e-06,4.23291518408704e-07,"G6PD/PTPN11/TERT/AKT1/NOS1/INSR/SNCA/F2/ABL1/MAPK14/CFTR/PSEN1",12
"GO:0070507","BP","GO:0070507","regulation of microtubule cytoskeleton organization","12/173","215/21081",2.24341812062475e-07,1.08691945205639e-06,4.23291518408704e-07,"GSK3B/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SNCA/RHOA/ABL1/MAPT/MAPT/MAPT",12
"GO:0019079","BP","GO:0019079","viral genome replication","10/173","139/21081",2.28529929336421e-07,1.10343598835279e-06,4.29723742723509e-07,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CXCL8/VCP",10
"GO:0035305","BP","GO:0035305","negative regulation of dephosphorylation","10/173","139/21081",2.28529929336421e-07,1.10343598835279e-06,4.29723742723509e-07,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GSK3B/IKBKB",10
"GO:0046683","BP","GO:0046683","response to organophosphorus","10/173","139/21081",2.28529929336421e-07,1.10343598835279e-06,4.29723742723509e-07,"SRD5A1/SLC6A3/SLC6A3/PTGS2/PIK3CG/AKR1C1/NOX4/TYR/APP/CFTR",10
"GO:0009135","BP","GO:0009135","purine nucleoside diphosphate metabolic process","10/173","140/21081",2.4438289976503e-07,1.17597162072663e-06,4.57972126638407e-07,"PPARA/HTR2A/HDAC4/INSR/STAT3/APP/PFKFB3/OGT/EP300/PSEN1",10
"GO:0009179","BP","GO:0009179","purine ribonucleoside diphosphate metabolic process","10/173","140/21081",2.4438289976503e-07,1.17597162072663e-06,4.57972126638407e-07,"PPARA/HTR2A/HDAC4/INSR/STAT3/APP/PFKFB3/OGT/EP300/PSEN1",10
"GO:0010633","BP","GO:0010633","negative regulation of epithelial cell migration","10/173","140/21081",2.4438289976503e-07,1.17597162072663e-06,4.57972126638407e-07,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPARG/RHOA",10
"GO:0050679","BP","GO:0050679","positive regulation of epithelial cell proliferation","12/173","217/21081",2.47910539186361e-07,1.19159715045571e-06,4.64057356038293e-07,"AGTR1/ERBB2/PRKCA/MTOR/AKT1/TLR4/EGFR/CCND1/SIRT1/STAT3/MMP12/C5AR1",12
"GO:0015872","BP","GO:0015872","dopamine transport","7/173","53/21081",2.48943070814732e-07,1.19297838021151e-06,4.64595264196529e-07,"SLC6A3/SLC6A3/DRD2/CNR1/DRD3/HTR2A/SNCA",7
"GO:0071622","BP","GO:0071622","regulation of granulocyte chemotaxis","7/173","53/21081",2.48943070814732e-07,1.19297838021151e-06,4.64595264196529e-07,"MAPK3/MAPK1/PTK2/CXCL8/MAPK14/DPP4/C5AR1",7
"GO:0003015","BP","GO:0003015","heart process","14/173","306/21081",2.49040203164889e-07,1.19297838021151e-06,4.64595264196529e-07,"DRD2/MDM2/SRC/MTOR/PIK3CA/PIK3CG/NOS3/NOS1/HDAC4/ACE/GLP1R/NOX4/IL2/CACNA1B",14
"GO:0060193","BP","GO:0060193","positive regulation of lipase activity","8/173","78/21081",2.5153378202866e-07,1.20221264323935e-06,4.68191469242856e-07,"ESR1/NR1H3/AGTR1/NR1H2/HTR2A/EGFR/RHOA/C5AR1",8
"GO:0090307","BP","GO:0090307","mitotic spindle assembly","8/173","78/21081",2.5153378202866e-07,1.20221264323935e-06,4.68191469242856e-07,"XIAP/CHEK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/RHOA",8
"GO:0010743","BP","GO:0010743","regulation of macrophage derived foam cell differentiation","6/173","33/21081",2.58071293261837e-07,1.23069015159321e-06,4.79281792199904e-07,"PPARA/NR1H3/PPARG/AGTR1/NR1H2/CETP",6
"GO:0046320","BP","GO:0046320","regulation of fatty acid oxidation","6/173","33/21081",2.58071293261837e-07,1.23069015159321e-06,4.79281792199904e-07,"PPARA/FABP1/CNR1/PPARG/MTOR/AKT1",6
"GO:0061138","BP","GO:0061138","morphogenesis of a branching epithelium","12/173","218/21081",2.60502536840605e-07,1.2408915684257e-06,4.83254647053847e-07,"ESR1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SRC/PPP1CA/ABL1",12
"GO:0008637","BP","GO:0008637","apoptotic mitochondrial changes","10/173","142/21081",2.79009741438961e-07,1.32756146850408e-06,5.17007501080977e-07,"BCL2L1/MAPK8/GSK3B/AKT1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/MMP9",10
"GO:0009185","BP","GO:0009185","ribonucleoside diphosphate metabolic process","10/173","143/21081",2.97883907061203e-07,1.4141996883833e-06,5.50748017524505e-07,"PPARA/HTR2A/HDAC4/INSR/STAT3/APP/PFKFB3/OGT/EP300/PSEN1",10
"GO:0009410","BP","GO:0009410","response to xenobiotic stimulus","10/173","143/21081",2.97883907061203e-07,1.4141996883833e-06,5.50748017524505e-07,"NR1I2/PTGS1/CES1/CES1/RORA/NQO1/CYP26A1/AKR1C1/EPHX1/CYP1B1",10
"GO:1905330","BP","GO:1905330","regulation of morphogenesis of an epithelium","12/173","221/21081",3.01768773990844e-07,1.43104410790971e-06,5.57307933169181e-07,"ESR1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MTOR/RHOA/ABL1",12
"GO:0007269","BP","GO:0007269","neurotransmitter secretion","11/173","181/21081",3.11033524089457e-07,1.46781398475559e-06,5.71627648371947e-07,"BACE1/DRD2/CNR1/PRKCB/GSK3B/HTR2A/CHRNA3/LRRK2/SNCA/CACNA1B/PSEN1",11
"GO:0099643","BP","GO:0099643","signal release from synapse","11/173","181/21081",3.11033524089457e-07,1.46781398475559e-06,5.71627648371947e-07,"BACE1/DRD2/CNR1/PRKCB/GSK3B/HTR2A/CHRNA3/LRRK2/SNCA/CACNA1B/PSEN1",11
"GO:0043276","BP","GO:0043276","anoikis","6/173","34/21081",3.11249800015247e-07,1.46781398475559e-06,5.71627648371947e-07,"SRC/CHEK2/MTOR/PIK3CA/AKT1/PTK2",6
"GO:0045907","BP","GO:0045907","positive regulation of vasoconstriction","6/173","34/21081",3.11249800015247e-07,1.46781398475559e-06,5.71627648371947e-07,"PTGS2/HTR2A/AKT1/EGFR/RHOA/CD38",6
"GO:0098810","BP","GO:0098810","neurotransmitter reuptake","6/173","34/21081",3.11249800015247e-07,1.46781398475559e-06,5.71627648371947e-07,"SLC6A3/SLC6A3/DRD2/DRD3/NOS1/SNCA",6
"GO:0044070","BP","GO:0044070","regulation of anion transport","9/173","110/21081",3.12772895871289e-07,1.47172982785948e-06,5.73152640099862e-07,"CES1/CES1/MTOR/AKT1/MIF/MIF/CFTR/CETP/PSEN1",9
"GO:0045069","BP","GO:0045069","regulation of viral genome replication","9/173","110/21081",3.12772895871289e-07,1.47172982785948e-06,5.73152640099862e-07,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CXCL8",9
"GO:0016051","BP","GO:0016051","carbohydrate biosynthetic process","12/173","222/21081",3.16763970072999e-07,1.48886073986745e-06,5.79824127800133e-07,"G6PD/PPARA/GSK3B/MTOR/AKT1/AKR1B1/INSR/SNCA/PPP1CA/SIRT1/OGT/EP300",12
"GO:0061136","BP","GO:0061136","regulation of proteasomal protein catabolic process","12/173","223/21081",3.32419132098339e-07,1.56071700805065e-06,6.07807939120197e-07,"MDM2/GSK3B/AKT1/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/OGT/VCP/PSEN1",12
"GO:0071260","BP","GO:0071260","cellular response to mechanical stimulus","8/173","81/21081",3.37922295646488e-07,1.58480334900875e-06,6.17188159354338e-07,"MAPK3/PTPN11/MAPK8/PTGS2/AKT1/TLR4/EGFR/HDAC4",8
"GO:0002262","BP","GO:0002262","myeloid cell homeostasis","11/173","183/21081",3.47274625764115e-07,1.6268686713029e-06,6.33570140661742e-07,"G6PD/IL6/PRMT1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/STAT5B/STAT3/MAPK14",11
"GO:0046718","BP","GO:0046718","viral entry into host cell","11/173","184/21081",3.66757338317387e-07,1.71495041534118e-06,6.67872825288015e-07,"HTR2A/EGFR/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/CTSB/CTSB/CDK1/DPP4",11
"GO:1901028","BP","GO:1901028","regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway","7/173","56/21081",3.66883955647243e-07,1.71495041534118e-06,6.67872825288015e-07,"MAPK8/GSK3B/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",7
"GO:0046513","BP","GO:0046513","ceramide biosynthetic process","8/173","82/21081",3.71857618352123e-07,1.735589420525e-06,6.75910509981371e-07,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:1903265","BP","GO:1903265","positive regulation of tumor necrosis factor-mediated signaling pathway","5/173","19/21081",3.72116253729884e-07,1.735589420525e-06,6.75910509981371e-07,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",5
"GO:0055094","BP","GO:0055094","response to lipoprotein particle","6/173","35/21081",3.73102313215392e-07,1.7382804044432e-06,6.76958490737069e-07,"CES1/CES1/SREBF2/PPARG/AKT1/TLR4",6
"GO:0051604","BP","GO:0051604","protein maturation","14/173","317/21081",3.81736354374638e-07,1.77655834582458e-06,6.91865508822196e-07,"CES1/CES1/SERPINE1/MDM2/XIAP/SRC/PARP1/LRRK2/ACE/CTSG/PSEN2/OGT/EP300/PSEN1",14
"GO:0050728","BP","GO:0050728","negative regulation of inflammatory response","12/173","228/21081",4.21506019558315e-07,1.95949570799046e-06,7.63108905615192e-07,"CYP19A1/NR1H4/PPARA/ALOX5/ALOX5/RORA/NR1H3/PPARG/F2/IL2/ELANE/ELANE",12
"GO:0006638","BP","GO:0006638","neutral lipid metabolic process","10/173","149/21081",4.3648075877081e-07,2.02247191277772e-06,7.87634451917251e-07,"FABP4/FABP5/FABP1/PTPN11/NR1H3/NR1H2/PIK3CG/SIRT1/MGLL/CETP",10
"GO:0006639","BP","GO:0006639","acylglycerol metabolic process","10/173","149/21081",4.3648075877081e-07,2.02247191277772e-06,7.87634451917251e-07,"FABP4/FABP5/FABP1/PTPN11/NR1H3/NR1H2/PIK3CG/SIRT1/MGLL/CETP",10
"GO:0030218","BP","GO:0030218","erythrocyte differentiation","10/173","149/21081",4.3648075877081e-07,2.02247191277772e-06,7.87634451917251e-07,"G6PD/PRMT1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/STAT5B/STAT3/MAPK14",10
"GO:1902806","BP","GO:1902806","regulation of cell cycle G1/S phase transition","12/173","229/21081",4.41679782643055e-07,2.04433267587183e-06,7.96147939817547e-07,"TERT/MDM2/CDK2/PRMT1/CHEK2/CDK4/WEE1/AKT1/EGFR/CCND1/CDK1/EP300",12
"GO:0001963","BP","GO:0001963","synaptic transmission, dopaminergic","6/173","36/21081",4.446909790089e-07,2.05603043504768e-06,8.00703532446012e-07,"SLC6A3/SLC6A3/DRD2/PTGS2/DRD3/SNCA",6
"GO:1901215","BP","GO:1901215","negative regulation of neuron death","13/173","274/21081",4.49967695586617e-07,2.07816602016036e-06,8.09324047439544e-07,"PPARA/BCL2L1/TERT/GSK3B/PIK3CA/AKT1/LRRK2/SNCA/RHOA/SIRT1/STAT3/C5AR1/PSEN1",13
"GO:0031668","BP","GO:0031668","cellular response to extracellular stimulus","13/173","275/21081",4.68961345052791e-07,2.16353610763226e-06,8.42570700523445e-07,"NR1H4/PPARA/SRD5A1/MAPK3/SREBF2/MAPK8/MDM2/PPARG/MTOR/MAPK1/PIM1/LRRK2/SIRT1",13
"GO:0002705","BP","GO:0002705","positive regulation of leukocyte mediated immunity","12/173","231/21081",4.84621629656808e-07,2.23335933233381e-06,8.69762760384179e-07,"NOS2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/STAT5B/IL2",12
"GO:0010759","BP","GO:0010759","positive regulation of macrophage chemotaxis","5/173","20/21081",4.92866262235665e-07,2.26398783593442e-06,8.81690770110344e-07,"MAPK3/MAPK1/PTK2/MAPK14/C5AR1",5
"GO:0090084","BP","GO:0090084","negative regulation of inclusion body assembly","5/173","20/21081",4.92866262235665e-07,2.26398783593442e-06,8.81690770110344e-07,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",5
"GO:0090494","BP","GO:0090494","dopamine uptake","5/173","20/21081",4.92866262235665e-07,2.26398783593442e-06,8.81690770110344e-07,"SLC6A3/SLC6A3/DRD2/DRD3/SNCA",5
"GO:0042542","BP","GO:0042542","response to hydrogen peroxide","10/173","151/21081",4.93825946558744e-07,2.26594648696339e-06,8.82453550062914e-07,"FABP1/MDM2/IL6/SRC/NQO1/LRRK2/SIRT1/ABL1/CYP1B1/CDK1",10
"GO:0001893","BP","GO:0001893","maternal placenta development","6/173","37/21081",5.27166494486067e-07,2.41371814124063e-06,9.40001961583596e-07,"MAPK3/PTGS2/MAPK1/AKT1/CTSB/CTSB",6
"GO:0071402","BP","GO:0071402","cellular response to lipoprotein particle stimulus","6/173","37/21081",5.27166494486067e-07,2.41371814124063e-06,9.40001961583596e-07,"CES1/CES1/SREBF2/PPARG/AKT1/TLR4",6
"GO:0032386","BP","GO:0032386","regulation of intracellular transport","15/173","376/21081",5.27989757653968e-07,2.41488533936675e-06,9.40456516947525e-07,"MAPK3/PTPN11/SREBF2/MAPK8/MDM2/PTGS2/SRC/GSK3B/ERBB2/CSNK2A2/MAPK1/LRRK2/MAPK14/CDK1/PSEN1",15
"GO:0034440","BP","GO:0034440","lipid oxidation","9/173","117/21081",5.29694910329636e-07,2.42007921934476e-06,9.42479229245261e-07,"PPARA/FABP1/ALOX5/ALOX5/CNR1/PPARG/MTOR/AKT1/MAPK14",9
"GO:0031396","BP","GO:0031396","regulation of protein ubiquitination","12/173","233/21081",5.31236521855499e-07,2.42451555463374e-06,9.44206922219283e-07,"XIAP/MTOR/AKT1/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/ABL1/OGT/PSEN1",12
"GO:0033157","BP","GO:0033157","regulation of intracellular protein transport","13/173","279/21081",5.52312715011331e-07,2.51800077905917e-06,9.80613946236517e-07,"PTPN11/SREBF2/MAPK8/MDM2/PTGS2/GSK3B/ERBB2/CSNK2A2/MAPK1/LRRK2/MAPK14/CDK1/PSEN1",13
"GO:0002824","BP","GO:0002824","positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains","10/173","153/21081",5.57663995821183e-07,2.53967236682123e-06,9.89053761415806e-07,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/IL2",10
"GO:0090316","BP","GO:0090316","positive regulation of intracellular protein transport","11/173","192/21081",5.60776430400223e-07,2.55111247619973e-06,9.93509014526261e-07,"SREBF2/MAPK8/MDM2/PTGS2/GSK3B/ERBB2/CSNK2A2/MAPK1/MAPK14/CDK1/PSEN1",11
"GO:0030330","BP","GO:0030330","DNA damage response, signal transduction by p53 class mediator","9/173","118/21081",5.69428905693425e-07,2.58770419282499e-06,1.0077593467493e-06,"MDM2/CDK2/PRMT1/CHEK2/MIF/MIF/SIRT1/CDK1/EP300",9
"GO:0014074","BP","GO:0014074","response to purine-containing compound","10/173","154/21081",5.92208979732347e-07,2.68835037914823e-06,1.04695514635543e-06,"SRD5A1/SLC6A3/SLC6A3/PPARG/PTGS2/PIK3CG/NOX4/TYR/APP/CFTR",10
"GO:0071398","BP","GO:0071398","cellular response to fatty acid","7/173","60/21081",5.94353008069494e-07,2.69520376871641e-06,1.04962414052153e-06,"NR1H4/PPARG/SRC/CDK4/AKT1/ACACA/ACACA",7
"GO:0045923","BP","GO:0045923","positive regulation of fatty acid metabolic process","6/173","38/21081",6.2177203741817e-07,2.81653452770768e-06,1.09687537068944e-06,"PPARA/FABP1/NR1H3/PPARG/PTGS2/NR1H2",6
"GO:0031998","BP","GO:0031998","regulation of fatty acid beta-oxidation","5/173","21/21081",6.42599770124132e-07,2.90430940709445e-06,1.13105854949213e-06,"PPARA/FABP1/CNR1/MTOR/AKT1",5
"GO:0090493","BP","GO:0090493","catecholamine uptake","5/173","21/21081",6.42599770124132e-07,2.90430940709445e-06,1.13105854949213e-06,"SLC6A3/SLC6A3/DRD2/DRD3/SNCA",5
"GO:0034113","BP","GO:0034113","heterotypic cell-cell adhesion","8/173","88/21081",6.43199612161892e-07,2.90430940709445e-06,1.13105854949213e-06,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0007178","BP","GO:0007178","transmembrane receptor protein serine/threonine kinase signaling pathway","15/173","382/21081",6.44534814253613e-07,2.90724885962166e-06,1.13220329423028e-06,"MAPK3/XIAP/SRC/PARP1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/PTK2/RHOA/SIRT1/ABL1/MAPK14/EP300",15
"GO:0015695","BP","GO:0015695","organic cation transport","7/173","61/21081",6.66788913739775e-07,3.00125645601727e-06,1.16881375155991e-06,"CNR1/HTR1A/CHRNA3/NOS1/SNCA/MAOB/PSEN1",7
"GO:0062208","BP","GO:0062208","positive regulation of pattern recognition receptor signaling pathway","7/173","61/21081",6.66788913739775e-07,3.00125645601727e-06,1.16881375155991e-06,"NR1H3/TLR4/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",7
"GO:0050817","BP","GO:0050817","coagulation","15/173","384/21081",6.88250350469398e-07,3.09457750174018e-06,1.2051568375805e-06,"PLG/MAPK3/PTPN11/SERPINE1/IL6/PRKCB/SRC/PRKCA/PIK3CA/PIK3CG/MAPK1/NOS3/TLR4/F2/PSEN1",15
"GO:0001818","BP","GO:0001818","negative regulation of cytokine production","16/173","438/21081",7.01497904675017e-07,3.15080824203398e-06,1.22705542021712e-06,"NR1H4/IDO1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CSK/TLR4/F2/MC1R/ELANE/ELANE",16
"GO:0009132","BP","GO:0009132","nucleoside diphosphate metabolic process","10/173","158/21081",7.49834714825786e-07,3.36080981360207e-06,1.30883874273388e-06,"PPARA/HTR2A/HDAC4/INSR/STAT3/APP/PFKFB3/OGT/EP300/PSEN1",10
"GO:0034101","BP","GO:0034101","erythrocyte homeostasis","10/173","158/21081",7.49834714825786e-07,3.36080981360207e-06,1.30883874273388e-06,"G6PD/PRMT1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/STAT5B/STAT3/MAPK14",10
"GO:0002708","BP","GO:0002708","positive regulation of lymphocyte mediated immunity","11/173","198/21081",7.60872884258989e-07,3.40669007925864e-06,1.3267064212247e-06,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/STAT5B/IL2",11
"GO:0043242","BP","GO:0043242","negative regulation of protein-containing complex disassembly","8/173","90/21081",7.64957486167485e-07,3.42137300918489e-06,1.33242456316375e-06,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0031348","BP","GO:0031348","negative regulation of defense response","15/173","388/21081",7.8378697288422e-07,3.50190415119353e-06,1.36378673017211e-06,"CYP19A1/NR1H4/PPARA/ALOX5/ALOX5/RORA/NR1H3/DRD2/PPARG/NR1H2/F2/MMP12/IL2/ELANE/ELANE",15
"GO:0051924","BP","GO:0051924","regulation of calcium ion transport","13/173","288/21081",7.90063419981429e-07,3.52623894065241e-06,1.37326370655773e-06,"G6PD/DRD2/PTGS2/DRD3/PIK3CG/NOS3/NOS1/SNCA/F2/RHOA/ABL1/PSEN2/CACNA1B",13
"GO:0032273","BP","GO:0032273","positive regulation of protein polymerization","10/173","159/21081",7.94549502722697e-07,3.54254022777412e-06,1.3796121039157e-06,"MTOR/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/RHOA/MAPT/MAPT/MAPT",10
"GO:0006672","BP","GO:0006672","ceramide metabolic process","9/173","123/21081",8.09270700508026e-07,3.60061906435456e-06,1.40223041190258e-06,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPP2CA",9
"GO:0046660","BP","GO:0046660","female sex differentiation","9/173","123/21081",8.09270700508026e-07,3.60061906435456e-06,1.40223041190258e-06,"CYP19A1/SRD5A1/ESR1/BCL2L1/SRC/NOS3/INSR/SIRT1/STAT5B",9
"GO:0010875","BP","GO:0010875","positive regulation of cholesterol efflux","5/173","22/21081",8.26089187986051e-07,3.6716035143857e-06,1.42987470107253e-06,"CES1/CES1/NR1H3/NR1H2/SIRT1",5
"GO:0016572","BP","GO:0016572","histone phosphorylation","6/173","40/21081",8.52831877817921e-07,3.78650224540057e-06,1.47462103275562e-06,"MAPK3/PRKCB/PRKCA/CDK2/CCNA2/CDK1",6
"GO:0042420","BP","GO:0042420","dopamine catabolic process","4/173","10/21081",8.85194296893427e-07,3.91790684114601e-06,1.52579543280314e-06,"SLC6A3/SLC6A3/MAOA/MAOB",4
"GO:0048312","BP","GO:0048312","intracellular distribution of mitochondria","4/173","10/21081",8.85194296893427e-07,3.91790684114601e-06,1.52579543280314e-06,"LRRK2/MAPT/MAPT/MAPT",4
"GO:0070943","BP","GO:0070943","neutrophil-mediated killing of symbiont cell","4/173","10/21081",8.85194296893427e-07,3.91790684114601e-06,1.52579543280314e-06,"F2/CTSG/ELANE/ELANE",4
"GO:0034754","BP","GO:0034754","cellular hormone metabolic process","10/173","161/21081",8.91021087783464e-07,3.93549750726813e-06,1.53264596782537e-06,"CYP19A1/AKR1B10/SRD5A1/ESR1/TTR/CYP26A1/AKR1B1/AKR1C1/STAT5B/CYP1B1",10
"GO:0046330","BP","GO:0046330","positive regulation of JNK cascade","10/173","161/21081",8.91021087783464e-07,3.93549750726813e-06,1.53264596782537e-06,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TLR4/APP",10
"GO:0033273","BP","GO:0033273","response to vitamin","8/173","92/21081",9.05873776198262e-07,3.99279841811869e-06,1.55496131926585e-06,"MDM2/PPARG/PTGS2/PIM1/CYP26A1/EGFR/CCND1/TYR",8
"GO:0048013","BP","GO:0048013","ephrin receptor signaling pathway","8/173","92/21081",9.05873776198262e-07,3.99279841811869e-06,1.55496131926585e-06,"PTPN11/SRC/PTK2/MMP9/RHOA/MMP2/PSEN2/PSEN1",8
"GO:1901796","BP","GO:1901796","regulation of signal transduction by p53 class mediator","11/173","202/21081",9.26991133555637e-07,4.07425195071971e-06,1.58668270343025e-06,"MDM2/CDK2/CSNK2A1/CSNK2A2/CHEK2/AKT1/MIF/MIF/SIRT1/MAPK14/EP300",11
"GO:0016079","BP","GO:0016079","synaptic vesicle exocytosis","9/173","125/21081",9.2723032156883e-07,4.07425195071971e-06,1.58668270343025e-06,"BACE1/DRD2/CNR1/PRKCB/GSK3B/HTR2A/LRRK2/SNCA/PSEN1",9
"GO:0046620","BP","GO:0046620","regulation of organ growth","9/173","125/21081",9.2723032156883e-07,4.07425195071971e-06,1.58668270343025e-06,"G6PD/PPARA/MTOR/MAPK1/PIM1/AKT1/PTK2/MAPK14/CDK1",9
"GO:0070542","BP","GO:0070542","response to fatty acid","8/173","93/21081",9.84263171058378e-07,4.32038658453207e-06,1.68253773912981e-06,"NR1H4/PPARG/PTGS2/SRC/CDK4/AKT1/ACACA/ACACA",8
"GO:0001676","BP","GO:0001676","long-chain fatty acid metabolic process","9/173","126/21081",9.91588445985152e-07,4.34655284436763e-06,1.69272796604673e-06,"MAPK3/PTGS1/ALOX5/ALOX5/PTGS2/CBR1/EPHX1/CYP1B1/MGLL",9
"GO:1900371","BP","GO:1900371","regulation of purine nucleotide biosynthetic process","6/173","41/21081",9.92270242183244e-07,4.34655284436763e-06,1.69272796604673e-06,"NOS2/NOS3/PARP1/NOS1/STAT3/VCP",6
"GO:0033673","BP","GO:0033673","negative regulation of kinase activity","13/173","295/21081",1.03416712574052e-06,4.52495713815602e-06,1.7622059979887e-06,"FABP4/HMGCR/IGF1R/CSK/AKT1/SNCA/SIRT1/ABL1/MAPT/MAPT/MAPT/PPP2CA/PSEN1",13
"GO:0043030","BP","GO:0043030","regulation of macrophage activation","7/173","65/21081",1.03512787439107e-06,4.52495713815602e-06,1.7622059979887e-06,"RORA/NR1H3/IL6/TLR4/LRRK2/MIF/MIF",7
"GO:0043507","BP","GO:0043507","positive regulation of JUN kinase activity","8/173","94/21081",1.06836666781456e-06,4.66545731916143e-06,1.81692259620759e-06,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0009615","BP","GO:0009615","response to virus","15/173","399/21081",1.11116600789176e-06,4.84737614736355e-06,1.88776933362785e-06,"BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/SRC/IKBKB/CHUK/MAPK14/MMP12",15
"GO:0002920","BP","GO:0002920","regulation of humoral immune response","10/173","165/21081",1.11509198175169e-06,4.85951367226969e-06,1.89249618927251e-06,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/F2/C5AR1",10
"GO:0007626","BP","GO:0007626","locomotory behavior","11/173","206/21081",1.12426438075281e-06,4.89446655104376e-06,1.90610829005978e-06,"SLC6A3/SLC6A3/IDO1/DRD2/DRD3/MTOR/CHRNA3/LRRK2/APP/DPP4/CACNA1B",11
"GO:0030808","BP","GO:0030808","regulation of nucleotide biosynthetic process","6/173","42/21081",1.14981457065189e-06,4.99623423264662e-06,1.94574084644573e-06,"NOS2/NOS3/PARP1/NOS1/STAT3/VCP",6
"GO:0046626","BP","GO:0046626","regulation of insulin receptor signaling pathway","7/173","66/21081",1.14999225218367e-06,4.99623423264662e-06,1.94574084644573e-06,"NR1H4/PTPN11/PRKCB/SRC/CDK4/SIRT1/OGT",7
"GO:2001020","BP","GO:2001020","regulation of response to DNA damage stimulus","12/173","253/21081",1.26787080018113e-06,5.50274058219573e-06,2.14299542807885e-06,"BCL2L1/MDM2/CHEK2/PARP1/EGFR/MIF/MIF/SIRT1/ABL1/MAPT/MAPT/MAPT",12
"GO:0045453","BP","GO:0045453","bone resorption","7/173","67/21081",1.27534500754212e-06,5.52389494092401e-06,2.15123381281851e-06,"IL6/SRC/PRKCA/CSK/EGFR/NOX4/CD38",7
"GO:0097345","BP","GO:0097345","mitochondrial outer membrane permeabilization","7/173","67/21081",1.27534500754212e-06,5.52389494092401e-06,2.15123381281851e-06,"MAPK8/GSK3B/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",7
"GO:0007219","BP","GO:0007219","Notch signaling pathway","11/173","209/21081",1.29558781710386e-06,5.60585808032007e-06,2.18315365900661e-06,"NR1H4/SREBF2/SRC/NOS3/AKT1/EGFR/STAT3/APP/PSEN2/EP300/PSEN1",11
"GO:0070661","BP","GO:0070661","leukocyte proliferation","15/173","404/21081",1.29707324172467e-06,5.60657599602047e-06,2.18343324515841e-06,"MAPK3/IDO1/IL6/ERBB2/PIK3CG/MAPK1/TLR4/PTK2/MIF/MIF/ACE/STAT5B/ABL1/CD38/IL2",15
"GO:0045821","BP","GO:0045821","positive regulation of glycolytic process","5/173","24/21081",1.31572912408371e-06,5.68143602462569e-06,2.21258684537825e-06,"HTR2A/INSR/APP/PFKFB3/PSEN1",5
"GO:1903748","BP","GO:1903748","negative regulation of establishment of protein localization to mitochondrion","4/173","11/21081",1.38210915426731e-06,5.96201197612365e-06,2.32185475875844e-06,"LRRK2/MAPT/MAPT/MAPT",4
"GO:0032922","BP","GO:0032922","circadian regulation of gene expression","7/173","68/21081",1.41193991954361e-06,6.08451594131925e-06,2.36956288408514e-06,"PPARA/RORA/DRD2/DRD3/PPP1CA/SIRT1/OGT",7
"GO:0032271","BP","GO:0032271","regulation of protein polymerization","12/173","256/21081",1.43437839186907e-06,6.17494811251435e-06,2.40478092253844e-06,"MTOR/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SNCA/RHOA/ABL1/MAPT/MAPT/MAPT",12
"GO:1904950","BP","GO:1904950","negative regulation of establishment of protein localization","10/173","170/21081",1.46321544518811e-06,6.29271500668451e-06,2.45064423592128e-06,"HMGCR/PTPN11/NR1H3/DRD2/DRD3/CSK/LRRK2/MAPT/MAPT/MAPT",10
"GO:0051591","BP","GO:0051591","response to cAMP","8/173","98/21081",1.46892287447426e-06,6.31087289549153e-06,2.45771567098455e-06,"SRD5A1/SLC6A3/SLC6A3/PIK3CG/NOX4/TYR/APP/CFTR",8
"GO:0030111","BP","GO:0030111","regulation of Wnt signaling pathway","15/173","409/21081",1.51048318564188e-06,6.47633002602659e-06,2.52215154052689e-06,"ESR1/TERT/XIAP/SRC/GSK3B/CSNK2A1/LRRK2/EGFR/PPP1CA/ABL1/MAPK14/APP/PPP2CA/VCP/PSEN1",15
"GO:1902903","BP","GO:1902903","regulation of supramolecular fiber organization","15/173","409/21081",1.51048318564188e-06,6.47633002602659e-06,2.52215154052689e-06,"MTOR/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SNCA/RHOA/ABL1/NOX4/APP/MAPT/MAPT/MAPT/PSEN1",15
"GO:0072659","BP","GO:0072659","protein localization to plasma membrane","13/173","306/21081",1.5548905453097e-06,6.65079316666558e-06,2.59009472395939e-06,"BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IKBKB/CSK/AKT1/EGFR",13
"GO:0051495","BP","GO:0051495","positive regulation of cytoskeleton organization","12/173","258/21081",1.55586924162523e-06,6.65079316666558e-06,2.59009472395939e-06,"MTOR/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/RHOA/ABL1/NOX4/MAPT/MAPT/MAPT",12
"GO:0070555","BP","GO:0070555","response to interleukin-1","12/173","258/21081",1.55586924162523e-06,6.65079316666558e-06,2.59009472395939e-06,"MAPK3/RORA/IL6/SRC/PRKCA/IKBKB/CHUK/HDAC4/SNCA/CXCL8/APP/CD38",12
"GO:0048167","BP","GO:0048167","regulation of synaptic plasticity","11/173","213/21081",1.55953665321476e-06,6.65749268437431e-06,2.59270379404105e-06,"DRD2/PTGS2/GSK3B/MAPK1/ABL1/APP/CD38/MAPT/MAPT/MAPT/PSEN1",11
"GO:0046824","BP","GO:0046824","positive regulation of nucleocytoplasmic transport","7/173","69/21081",1.56057018442853e-06,6.65749268437431e-06,2.59270379404105e-06,"MDM2/PTGS2/GSK3B/MAPK1/MAPK14/CDK1/PSEN1",7
"GO:0097306","BP","GO:0097306","cellular response to alcohol","8/173","99/21081",1.58698687081144e-06,6.76339740629669e-06,2.63394748552561e-06,"CES1/CES1/PPARG/CDK4/AKT1/CFTR/ACACA/ACACA",8
"GO:0072331","BP","GO:0072331","signal transduction by p53 class mediator","13/173","307/21081",1.61218752582545e-06,6.86391262247729e-06,2.67309227992575e-06,"MDM2/CDK2/PRMT1/CSNK2A1/CSNK2A2/CHEK2/AKT1/MIF/MIF/SIRT1/MAPK14/CDK1/EP300",13
"GO:0007179","BP","GO:0007179","transforming growth factor beta receptor signaling pathway","11/173","214/21081",1.63248412447056e-06,6.90734483252485e-06,2.69000658402077e-06,"SRC/PARP1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/PTK2/RHOA/SIRT1/EP300",11
"GO:0016052","BP","GO:0016052","carbohydrate catabolic process","11/173","214/21081",1.63248412447056e-06,6.90734483252485e-06,2.69000658402077e-06,"PPARA/HTR2A/HDAC4/INSR/PPP1CA/STAT3/APP/PFKFB3/OGT/EP300/PSEN1",11
"GO:0006837","BP","GO:0006837","serotonin transport","5/173","25/21081",1.63376831176453e-06,6.90734483252485e-06,2.69000658402077e-06,"CNR1/HTR1A/NOS1/SNCA/MAOB",5
"GO:0030810","BP","GO:0030810","positive regulation of nucleotide biosynthetic process","5/173","25/21081",1.63376831176453e-06,6.90734483252485e-06,2.69000658402077e-06,"NOS2/NOS3/NOS1/STAT3/VCP",5
"GO:0090083","BP","GO:0090083","regulation of inclusion body assembly","5/173","25/21081",1.63376831176453e-06,6.90734483252485e-06,2.69000658402077e-06,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",5
"GO:1900373","BP","GO:1900373","positive regulation of purine nucleotide biosynthetic process","5/173","25/21081",1.63376831176453e-06,6.90734483252485e-06,2.69000658402077e-06,"NOS2/NOS3/NOS1/STAT3/VCP",5
"GO:1901673","BP","GO:1901673","regulation of mitotic spindle assembly","5/173","25/21081",1.63376831176453e-06,6.90734483252485e-06,2.69000658402077e-06,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",5
"GO:0044242","BP","GO:0044242","cellular lipid catabolic process","12/173","260/21081",1.68637994890888e-06,7.11561906942783e-06,2.77111721077171e-06,"AKR1B10/FABP4/FABP5/PPARA/FABP1/CNR1/MTOR/PIK3CG/CYP26A1/AKT1/CYP1B1/MGLL",12
"GO:0071453","BP","GO:0071453","cellular response to oxygen levels","12/173","260/21081",1.68637994890888e-06,7.11561906942783e-06,2.77111721077171e-06,"FABP1/RORA/TERT/MDM2/PPARG/PTGS2/SRC/MTOR/CCNA2/AKT1/SIRT1/EP300",12
"GO:1901992","BP","GO:1901992","positive regulation of mitotic cell cycle phase transition","8/173","100/21081",1.71303491352473e-06,7.22091800353828e-06,2.81212498335514e-06,"TERT/MDM2/CDK4/AKT1/EGFR/CCND1/CDK1/APP",8
"GO:0140014","BP","GO:0140014","mitotic nuclear division","13/173","309/21081",1.73244895065995e-06,7.29551594782372e-06,2.84117651706999e-06,"XIAP/PRKCB/DRD3/PRKCA/CHEK2/INSR/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/RHOA/CDK1",13
"GO:0007052","BP","GO:0007052","mitotic spindle organization","9/173","135/21081",1.76721203021224e-06,7.43453853106118e-06,2.89531767742953e-06,"XIAP/CHEK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/RHOA/VCP",9
"GO:0030308","BP","GO:0030308","negative regulation of cell growth","11/173","216/21081",1.78742821700339e-06,7.51214885662452e-06,2.92554235736303e-06,"G6PD/PPARA/ESR2/PPARG/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SIRT1/PPP2CA",11
"GO:0006476","BP","GO:0006476","protein deacetylation","8/173","101/21081",1.84750455693072e-06,7.75696330276545e-06,3.02088325722394e-06,"MAPK8/LRRK2/HDAC4/SIRT1/MAPT/MAPT/MAPT/EP300",8
"GO:2000134","BP","GO:2000134","negative regulation of G1/S transition of mitotic cell cycle","9/173","136/21081",1.87924849438505e-06,7.88245493844231e-06,3.0697549053601e-06,"MDM2/CDK2/PRMT1/CHEK2/CDK4/WEE1/CCND1/CDK1/EP300",9
"GO:0001933","BP","GO:0001933","negative regulation of protein phosphorylation","16/173","473/21081",1.91211578580142e-06,8.01240628586808e-06,3.1203633502334e-06,"FABP4/HMGCR/IGF1R/DRD2/CSK/MTOR/AKT1/TLR4/LRRK2/XDH/SNCA/SIRT1/ABL1/IL2/PPP2CA/PSEN1",16
"GO:0006816","BP","GO:0006816","calcium ion transport","16/173","474/21081",1.96493875879944e-06,8.225640183388e-06,3.2034054745478e-06,"G6PD/DRD2/PTGS2/PRKCB/DRD3/HTR2A/PIK3CG/NOS3/NOS1/SNCA/F2/RHOA/ABL1/PSEN2/CACNA1B/PSEN1",16
"GO:0008585","BP","GO:0008585","female gonad development","8/173","102/21081",1.99085158874272e-06,8.32591378008643e-06,3.24245617229958e-06,"CYP19A1/ESR1/BCL2L1/SRC/NOS3/INSR/SIRT1/STAT5B",8
"GO:0062207","BP","GO:0062207","regulation of pattern recognition receptor signaling pathway","9/173","137/21081",1.99735516051532e-06,8.33161791237281e-06,3.24467759801069e-06,"ESR1/NR1H3/XIAP/TLR4/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",9
"GO:0045124","BP","GO:0045124","regulation of bone resorption","6/173","46/21081",1.99809805900398e-06,8.33161791237281e-06,3.24467759801069e-06,"IL6/SRC/PRKCA/CSK/EGFR/CD38",6
"GO:0140353","BP","GO:0140353","lipid export from cell","6/173","46/21081",1.99809805900398e-06,8.33161791237281e-06,3.24467759801069e-06,"CYP19A1/PTPN11/NOS2/AGTR1/MIF/MIF",6
"GO:0046697","BP","GO:0046697","decidualization","5/173","26/21081",2.00936550339618e-06,8.36218807436863e-06,3.25658288709603e-06,"MAPK3/PTGS2/MAPK1/CTSB/CTSB",5
"GO:0090335","BP","GO:0090335","regulation of brown fat cell differentiation","5/173","26/21081",2.00936550339618e-06,8.36218807436863e-06,3.25658288709603e-06,"PTGS2/MTOR/PIM1/SIRT1/MAPK14",5
"GO:0007162","BP","GO:0007162","negative regulation of cell adhesion","14/173","365/21081",2.03308615434988e-06,8.45262531294781e-06,3.29180289899889e-06,"PPARA/PLG/PTPN11/IDO1/SERPINE1/SRC/ERBB2/AKT1/PTK2/RHOA/ABL1/CYP1B1/MMP12/IL2",14
"GO:0071560","BP","GO:0071560","cellular response to transforming growth factor beta stimulus","12/173","265/21081",2.05595627301944e-06,8.52235521589463e-06,3.31895861549748e-06,"SRC/PARP1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/PTK2/RHOA/SIRT1/NOX4/EP300",12
"GO:0019614","BP","GO:0019614","catechol-containing compound catabolic process","4/173","12/21081",2.05988675140593e-06,8.52235521589463e-06,3.31895861549748e-06,"SLC6A3/SLC6A3/MAOA/MAOB",4
"GO:0042424","BP","GO:0042424","catecholamine catabolic process","4/173","12/21081",2.05988675140593e-06,8.52235521589463e-06,3.31895861549748e-06,"SLC6A3/SLC6A3/MAOA/MAOB",4
"GO:0070942","BP","GO:0070942","neutrophil mediated cytotoxicity","4/173","12/21081",2.05988675140593e-06,8.52235521589463e-06,3.31895861549748e-06,"F2/CTSG/ELANE/ELANE",4
"GO:0090043","BP","GO:0090043","regulation of tubulin deacetylation","4/173","12/21081",2.05988675140593e-06,8.52235521589463e-06,3.31895861549748e-06,"MAPT/MAPT/MAPT/EP300",4
"GO:0031571","BP","GO:0031571","mitotic G1 DNA damage checkpoint","7/173","72/21081",2.08722264906783e-06,8.6270515913319e-06,3.35973172674035e-06,"MDM2/CDK2/PRMT1/CHEK2/CCND1/CDK1/EP300",7
"GO:1990778","BP","GO:1990778","protein localization to cell periphery","14/173","366/21081",2.09902016235012e-06,8.66738257514643e-06,3.37543828470605e-06,"BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IKBKB/CSK/AKT1/EGFR/MAPK10",14
"GO:0044783","BP","GO:0044783","G1 DNA damage checkpoint","7/173","73/21081",2.29275859666656e-06,9.43985588879477e-06,3.67627143406755e-06,"MDM2/CDK2/PRMT1/CHEK2/CCND1/CDK1/EP300",7
"GO:0044819","BP","GO:0044819","mitotic G1/S transition checkpoint","7/173","73/21081",2.29275859666656e-06,9.43985588879477e-06,3.67627143406755e-06,"MDM2/CDK2/PRMT1/CHEK2/CCND1/CDK1/EP300",7
"GO:1902110","BP","GO:1902110","positive regulation of mitochondrial membrane permeability involved in apoptotic process","7/173","73/21081",2.29275859666656e-06,9.43985588879477e-06,3.67627143406755e-06,"MAPK8/GSK3B/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",7
"GO:0051054","BP","GO:0051054","positive regulation of DNA metabolic process","11/173","222/21081",2.3325110360395e-06,9.58495105622035e-06,3.73277751059157e-06,"MAPK3/IL6/SRC/CDK2/MAPK1/AKT1/PARP1/EGFR/SIRT1/NOX4/IL2",11
"GO:0071383","BP","GO:0071383","cellular response to steroid hormone stimulus","11/173","222/21081",2.3325110360395e-06,9.58495105622035e-06,3.73277751059157e-06,"PPARA/SRD5A1/ESR1/ESR2/SRC/PARP1/EGFR/RHOA/SIRT1/ESRRA/EP300",11
"GO:1900078","BP","GO:1900078","positive regulation of cellular response to insulin stimulus","5/173","27/21081",2.4497112689925e-06,1.00568339922214e-05,3.91654829886215e-06,"NR1H4/PTPN11/SRC/SIRT1/ESRRA",5
"GO:0032374","BP","GO:0032374","regulation of cholesterol transport","7/173","74/21081",2.51493121324563e-06,1.0304669937397e-05,4.01306589577438e-06,"CES1/CES1/NR1H3/SREBF2/NR1H2/SIRT1/CETP",7
"GO:0033344","BP","GO:0033344","cholesterol efflux","7/173","74/21081",2.51493121324563e-06,1.0304669937397e-05,4.01306589577438e-06,"CES1/CES1/NR1H3/SREBF2/NR1H2/SIRT1/CETP",7
"GO:0090311","BP","GO:0090311","regulation of protein deacetylation","6/173","48/21081",2.58242910513593e-06,1.05710416837404e-05,4.11680210249841e-06,"MAPK8/LRRK2/MAPT/MAPT/MAPT/EP300",6
"GO:0071559","BP","GO:0071559","response to transforming growth factor beta","12/173","271/21081",2.59260212840105e-06,1.06024701093129e-05,4.12904163501996e-06,"SRC/PARP1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/PTK2/RHOA/SIRT1/NOX4/EP300",12
"GO:0045682","BP","GO:0045682","regulation of epidermis development","8/173","106/21081",2.66279591975106e-06,1.08686069769666e-05,4.23268637023981e-06,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0062014","BP","GO:0062014","negative regulation of small molecule metabolic process","8/173","106/21081",2.66279591975106e-06,1.08686069769666e-05,4.23268637023981e-06,"PPARA/CNR1/AKT1/PARP1/HDAC4/SIRT1/STAT3/EP300",8
"GO:1902807","BP","GO:1902807","negative regulation of cell cycle G1/S phase transition","9/173","142/21081",2.68880336317129e-06,1.09642279175766e-05,4.2699251307256e-06,"MDM2/CDK2/PRMT1/CHEK2/CDK4/WEE1/CCND1/CDK1/EP300",9
"GO:0010517","BP","GO:0010517","regulation of phospholipase activity","7/173","75/21081",2.75479675047357e-06,1.1190374180461e-05,4.35799586569836e-06,"ESR1/AGTR1/HTR2A/EGFR/SNCA/ABL1/C5AR1",7
"GO:0050795","BP","GO:0050795","regulation of behavior","7/173","75/21081",2.75479675047357e-06,1.1190374180461e-05,4.35799586569836e-06,"DRD2/CNR1/DRD3/HTR1A/MTOR/HDAC4/STAT3",7
"GO:0060760","BP","GO:0060760","positive regulation of response to cytokine stimulus","7/173","75/21081",2.75479675047357e-06,1.1190374180461e-05,4.35799586569836e-06,"TLR4/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/MMP12",7
"GO:1902686","BP","GO:1902686","mitochondrial outer membrane permeabilization involved in programmed cell death","7/173","75/21081",2.75479675047357e-06,1.1190374180461e-05,4.35799586569836e-06,"MAPK8/GSK3B/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",7
"GO:0007200","BP","GO:0007200","phospholipase C-activating G protein-coupled receptor signaling pathway","8/173","107/21081",2.85804048639766e-06,1.15765624658757e-05,4.5083936025459e-06,"ESR1/DRD2/AGTR1/DRD3/TACR1/HTR2A/F2/C5AR1",8
"GO:0046545","BP","GO:0046545","development of primary female sexual characteristics","8/173","107/21081",2.85804048639766e-06,1.15765624658757e-05,4.5083936025459e-06,"CYP19A1/ESR1/BCL2L1/SRC/NOS3/INSR/SIRT1/STAT5B",8
"GO:0046928","BP","GO:0046928","regulation of neurotransmitter secretion","8/173","107/21081",2.85804048639766e-06,1.15765624658757e-05,4.5083936025459e-06,"BACE1/DRD2/CNR1/PRKCB/GSK3B/HTR2A/CHRNA3/LRRK2",8
"GO:0009755","BP","GO:0009755","hormone-mediated signaling pathway","11/173","227/21081",2.89303286351864e-06,1.17071396543721e-05,4.55924577589104e-06,"PPARA/PTPN11/ESR1/ESR2/PPARG/SRC/PARP1/RHOA/SIRT1/ESRRA/EP300",11
"GO:0002002","BP","GO:0002002","regulation of angiotensin levels in blood","4/173","13/21081",2.95634137068526e-06,1.19292445242561e-05,4.64574262479855e-06,"CES1/CES1/ACE/CTSG",4
"GO:0002003","BP","GO:0002003","angiotensin maturation","4/173","13/21081",2.95634137068526e-06,1.19292445242561e-05,4.64574262479855e-06,"CES1/CES1/ACE/CTSG",4
"GO:0070857","BP","GO:0070857","regulation of bile acid biosynthetic process","4/173","13/21081",2.95634137068526e-06,1.19292445242561e-05,4.64574262479855e-06,"NR1H4/CES1/CES1/SIRT1",4
"GO:0010738","BP","GO:0010738","regulation of protein kinase A signaling","5/173","28/21081",2.96251409242915e-06,1.19428106060071e-05,4.65102581973297e-06,"PDE4A/LRRK2/MIF/MIF/MC1R",5
"GO:0007596","BP","GO:0007596","blood coagulation","14/173","378/21081",3.05315412180406e-06,1.2296542050754e-05,4.78878351656371e-06,"PLG/MAPK3/PTPN11/SERPINE1/IL6/PRKCB/SRC/PRKCA/PIK3CA/PIK3CG/MAPK1/NOS3/TLR4/F2",14
"GO:0032091","BP","GO:0032091","negative regulation of protein binding","8/173","109/21081",3.28519836793274e-06,1.31838122340581e-05,5.13432332857002e-06,"PPARA/MAPK3/MAPK8/GSK3B/AKT1/LRRK2/ACE/PPP1CA",8
"GO:0043506","BP","GO:0043506","regulation of JUN kinase activity","8/173","109/21081",3.28519836793274e-06,1.31838122340581e-05,5.13432332857002e-06,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0050829","BP","GO:0050829","defense response to Gram-negative bacterium","8/173","109/21081",3.28519836793274e-06,1.31838122340581e-05,5.13432332857002e-06,"NOS2/SERPINE1/IL6/TLR4/F2/CTSG/ELANE/ELANE",8
"GO:0035794","BP","GO:0035794","positive regulation of mitochondrial membrane permeability","7/173","77/21081",3.2920745540917e-06,1.31838122340581e-05,5.13432332857002e-06,"MAPK8/GSK3B/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",7
"GO:0043627","BP","GO:0043627","response to estrogen","7/173","77/21081",3.2920745540917e-06,1.31838122340581e-05,5.13432332857002e-06,"SRD5A1/ESR1/MDM2/PPARG/MAPK1/CCND1/EP300",7
"GO:0051937","BP","GO:0051937","catecholamine transport","7/173","77/21081",3.2920745540917e-06,1.31838122340581e-05,5.13432332857002e-06,"SLC6A3/SLC6A3/DRD2/CNR1/DRD3/HTR2A/SNCA",7
"GO:0032309","BP","GO:0032309","icosanoid secretion","6/173","50/21081",3.29898488622806e-06,1.31866291454215e-05,5.13542035069615e-06,"NOS2/DRD2/DRD3/MIF/MIF/ACE",6
"GO:0033628","BP","GO:0033628","regulation of cell adhesion mediated by integrin","6/173","50/21081",3.29898488622806e-06,1.31866291454215e-05,5.13542035069615e-06,"PTPN11/SERPINE1/PIK3CG/PTK2/CYP1B1/DPP4",6
"GO:0060562","BP","GO:0060562","epithelial tube morphogenesis","14/173","382/21081",3.44795592070133e-06,1.37691397622744e-05,5.36227414655965e-06,"ESR1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SRC/PPP1CA/RHOA/ABL1/PSEN1",14
"GO:0010959","BP","GO:0010959","regulation of metal ion transport","15/173","438/21081",3.49668434320796e-06,1.39506213843105e-05,5.43295061776419e-06,"G6PD/DRD2/PTGS2/DRD3/HTR2A/PIK3CG/NOS3/AKT1/NOS1/SNCA/F2/RHOA/ABL1/PSEN2/CACNA1B",15
"GO:0010575","BP","GO:0010575","positive regulation of vascular endothelial growth factor production","5/173","29/21081",3.55600994236597e-06,1.41607181303777e-05,5.51477100517862e-06,"RORA/PTGS2/IL6/CYP1B1/C5AR1",5
"GO:1905523","BP","GO:1905523","positive regulation of macrophage migration","5/173","29/21081",3.55600994236597e-06,1.41607181303777e-05,5.51477100517862e-06,"MAPK3/MAPK1/PTK2/MAPK14/C5AR1",5
"GO:0071456","BP","GO:0071456","cellular response to hypoxia","11/173","232/21081",3.56828148543052e-06,1.41830009650087e-05,5.52344886524227e-06,"FABP1/RORA/TERT/MDM2/PTGS2/SRC/MTOR/CCNA2/AKT1/SIRT1/EP300",11
"GO:0099003","BP","GO:0099003","vesicle-mediated transport in synapse","11/173","232/21081",3.56828148543052e-06,1.41830009650087e-05,5.52344886524227e-06,"BACE1/DRD2/CNR1/PRKCB/DRD3/GSK3B/HTR2A/LRRK2/SNCA/MAPK10/PSEN1",11
"GO:1902108","BP","GO:1902108","regulation of mitochondrial membrane permeability involved in apoptotic process","7/173","78/21081",3.59184617950636e-06,1.42633218847874e-05,5.55472916299459e-06,"MAPK8/GSK3B/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",7
"GO:0007599","BP","GO:0007599","hemostasis","14/173","384/21081",3.66191666943013e-06,1.45279961983274e-05,5.657804318978e-06,"PLG/MAPK3/PTPN11/SERPINE1/IL6/PRKCB/SRC/PRKCA/PIK3CA/PIK3CG/MAPK1/NOS3/TLR4/F2",14
"GO:0001504","BP","GO:0001504","neurotransmitter uptake","6/173","51/21081",3.71357296853809e-06,1.47191898724984e-05,5.73226306612517e-06,"SLC6A3/SLC6A3/DRD2/DRD3/NOS1/SNCA",6
"GO:0045926","BP","GO:0045926","negative regulation of growth","12/173","281/21081",3.76484828104433e-06,1.48966068015506e-05,5.80135657728447e-06,"G6PD/PPARA/ESR2/PPARG/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/PTK2/SIRT1/PPP2CA",12
"GO:0035601","BP","GO:0035601","protein deacylation","8/173","111/21081",3.76534612964589e-06,1.48966068015506e-05,5.80135657728447e-06,"MAPK8/LRRK2/HDAC4/SIRT1/MAPT/MAPT/MAPT/EP300",8
"GO:0032388","BP","GO:0032388","positive regulation of intracellular transport","11/173","234/21081",3.87477629723167e-06,1.53152785924999e-05,5.96440473855392e-06,"SREBF2/MAPK8/MDM2/PTGS2/GSK3B/ERBB2/CSNK2A2/MAPK1/MAPK14/CDK1/PSEN1",11
"GO:0002819","BP","GO:0002819","regulation of adaptive immune response","11/173","235/21081",4.03648519253412e-06,1.59396148541612e-05,6.20754717537042e-06,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/SIRT1/IL2",11
"GO:0048146","BP","GO:0048146","positive regulation of fibroblast proliferation","6/173","52/21081",4.1695748594423e-06,1.64498826163141e-05,6.40626660708918e-06,"ESR1/CDK4/CCNA2/EGFR/MIF/MIF",6
"GO:0009165","BP","GO:0009165","nucleotide biosynthetic process","12/173","284/21081",4.19748072172878e-06,1.65398958668961e-05,6.44132150047953e-06,"NOS2/IDO1/PTGS2/MAPK1/NOS3/PARP1/NOS1/STAT3/FASN/ACACA/ACACA/VCP",12
"GO:0044843","BP","GO:0044843","cell cycle G1/S phase transition","13/173","335/21081",4.20307019144434e-06,1.65398958668961e-05,6.44132150047953e-06,"TERT/MDM2/CDK2/PRMT1/CHEK2/CDK4/WEE1/CCNA2/AKT1/EGFR/CCND1/CDK1/EP300",13
"GO:0030100","BP","GO:0030100","regulation of endocytosis","11/173","236/21081",4.20406861290839e-06,1.65398958668961e-05,6.44132150047953e-06,"SERPINE1/NR1H3/DRD2/PPARG/NR1H2/DRD3/SRC/LRRK2/INSR/SNCA/ABL1",11
"GO:0001964","BP","GO:0001964","startle response","5/173","30/21081",4.23897109108787e-06,1.66156717398823e-05,6.47083176848916e-06,"SLC6A3/SLC6A3/BACE1/DRD2/DRD3",5
"GO:0043457","BP","GO:0043457","regulation of cellular respiration","5/173","30/21081",4.23897109108787e-06,1.66156717398823e-05,6.47083176848916e-06,"NOS2/PIK3CA/SNCA/CDK1/VCP",5
"GO:0050820","BP","GO:0050820","positive regulation of coagulation","5/173","30/21081",4.23897109108787e-06,1.66156717398823e-05,6.47083176848916e-06,"PLG/SERPINE1/TLR4/F2/PSEN1",5
"GO:0051131","BP","GO:0051131","chaperone-mediated protein complex assembly","5/173","30/21081",4.23897109108787e-06,1.66156717398823e-05,6.47083176848916e-06,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",5
"GO:1905710","BP","GO:1905710","positive regulation of membrane permeability","7/173","80/21081",4.25994308134915e-06,1.66824867766383e-05,6.49685231518882e-06,"MAPK8/GSK3B/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",7
"GO:0002690","BP","GO:0002690","positive regulation of leukocyte chemotaxis","8/173","113/21081",4.30372459296594e-06,1.6838421542829e-05,6.55757978108215e-06,"MAPK3/SERPINE1/IL6/MAPK1/PTK2/CXCL8/MAPK14/C5AR1",8
"GO:2000300","BP","GO:2000300","regulation of synaptic vesicle exocytosis","7/173","81/21081",4.63094504756429e-06,1.81020105861092e-05,7.04967376630133e-06,"BACE1/DRD2/CNR1/PRKCB/GSK3B/HTR2A/LRRK2",7
"GO:0050873","BP","GO:0050873","brown fat cell differentiation","6/173","53/21081",4.67008104522457e-06,1.82340901771348e-05,7.10111103750874e-06,"FABP4/PTGS2/MTOR/PIM1/SIRT1/MAPK14",6
"GO:1901293","BP","GO:1901293","nucleoside phosphate biosynthetic process","12/173","287/21081",4.67331706352078e-06,1.82340901771348e-05,7.10111103750874e-06,"NOS2/IDO1/PTGS2/MAPK1/NOS3/PARP1/NOS1/STAT3/FASN/ACACA/ACACA/VCP",12
"GO:0010639","BP","GO:0010639","negative regulation of organelle organization","15/173","449/21081",4.72042688889045e-06,1.84010035329317e-05,7.16611402157005e-06,"BCL2L1/SRC/AKT1/PARP1/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SNCA/SIRT1/MAPT/MAPT/MAPT",15
"GO:0002703","BP","GO:0002703","regulation of leukocyte mediated immunity","13/173","339/21081",4.78084362198503e-06,1.86194358843395e-05,7.25118063945243e-06,"NOS2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/TLR4/STAT5B/IL2",13
"GO:0043502","BP","GO:0043502","regulation of muscle adaptation","8/173","115/21081",4.90595955031232e-06,1.90892144040998e-05,7.43413188075088e-06,"G6PD/PPARA/PRKCA/MTOR/NOS3/PARP1/HDAC4/PTK2",8
"GO:0043401","BP","GO:0043401","steroid hormone mediated signaling pathway","9/173","153/21081",4.96594096711872e-06,1.93049251320105e-05,7.51813858555461e-06,"PPARA/ESR1/ESR2/SRC/PARP1/RHOA/SIRT1/ESRRA/EP300",9
"GO:2000027","BP","GO:2000027","regulation of animal organ morphogenesis","12/173","289/21081",5.01633679759864e-06,1.94644294209695e-05,7.58025617167234e-06,"ESR1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PIM1/RHOA/ABL1",12
"GO:0005979","BP","GO:0005979","regulation of glycogen biosynthetic process","5/173","31/21081",5.02071420225524e-06,1.94644294209695e-05,7.58025617167234e-06,"GSK3B/MTOR/AKT1/INSR/PPP1CA",5
"GO:0010962","BP","GO:0010962","regulation of glucan biosynthetic process","5/173","31/21081",5.02071420225524e-06,1.94644294209695e-05,7.58025617167234e-06,"GSK3B/MTOR/AKT1/INSR/PPP1CA",5
"GO:0046822","BP","GO:0046822","regulation of nucleocytoplasmic transport","8/173","116/21081",5.23289093156283e-06,2.02685082663724e-05,7.89339782604881e-06,"PTPN11/MDM2/PTGS2/GSK3B/MAPK1/MAPK14/CDK1/PSEN1",8
"GO:0036294","BP","GO:0036294","cellular response to decreased oxygen levels","11/173","243/21081",5.5573898922431e-06,2.15057829254471e-05,8.37524389857747e-06,"FABP1/RORA/TERT/MDM2/PTGS2/SRC/MTOR/CCNA2/AKT1/SIRT1/EP300",11
"GO:0019336","BP","GO:0019336","phenol-containing compound catabolic process","4/173","15/21081",5.57190801471222e-06,2.15423449995562e-05,8.38948268677516e-06,"SLC6A3/SLC6A3/MAOA/MAOB",4
"GO:1901989","BP","GO:1901989","positive regulation of cell cycle phase transition","8/173","117/21081",5.57807963036894e-06,2.15466003176706e-05,8.39113988415309e-06,"TERT/MDM2/CDK4/AKT1/EGFR/CCND1/CDK1/APP",8
"GO:0046850","BP","GO:0046850","regulation of bone remodeling","6/173","55/21081",5.81773317241508e-06,2.24519057671132e-05,8.74370337686936e-06,"IL6/SRC/PRKCA/CSK/EGFR/CD38",6
"GO:0038128","BP","GO:0038128","ERBB2 signaling pathway","5/173","32/21081",5.91110770813947e-06,2.27708945166678e-05,8.86793082711766e-06,"SRC/ERBB2/PRKCA/PIK3CA/EGFR",5
"GO:0090344","BP","GO:0090344","negative regulation of cell aging","5/173","32/21081",5.91110770813947e-06,2.27708945166678e-05,8.86793082711766e-06,"TERT/MIF/MIF/SIRT1/ABL1",5
"GO:0006606","BP","GO:0006606","protein import into nucleus","9/173","157/21081",6.12956451445075e-06,2.35697010152952e-05,9.17901921097078e-06,"PTGS2/MAPK1/AKT1/LRRK2/STAT3/MAPK14/CDK1/MMP12/PSEN1",9
"GO:0007006","BP","GO:0007006","mitochondrial membrane organization","9/173","157/21081",6.12956451445075e-06,2.35697010152952e-05,9.17901921097078e-06,"BCL2L1/MAPK8/GSK3B/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/STAT3",9
"GO:0022900","BP","GO:0022900","electron transport chain","10/173","200/21081",6.27171927857232e-06,2.40727508714126e-05,9.37492769069148e-06,"CYP19A1/SRD5A1/IDO1/XDH/AKR1B1/GSR/SNCA/MAOB/NOX4/CDK1",10
"GO:0071478","BP","GO:0071478","cellular response to radiation","10/173","200/21081",6.27171927857232e-06,2.40727508714126e-05,9.37492769069148e-06,"BCL2L1/MDM2/PTGS2/CHEK2/PARP1/MC1R/SIRT1/MAPK14/NOX4/EP300",10
"GO:1903747","BP","GO:1903747","regulation of establishment of protein localization to mitochondrion","7/173","85/21081",6.39517064802594e-06,2.45125371314021e-05,9.54619870200147e-06,"SREBF2/MAPK8/CSNK2A2/LRRK2/MAPT/MAPT/MAPT",7
"GO:0060047","BP","GO:0060047","heart contraction","12/173","296/21081",6.39783565044125e-06,2.45125371314021e-05,9.54619870200147e-06,"DRD2/MDM2/MTOR/PIK3CA/PIK3CG/NOS3/NOS1/HDAC4/ACE/GLP1R/IL2/CACNA1B",12
"GO:0098693","BP","GO:0098693","regulation of synaptic vesicle cycle","8/173","120/21081",6.73152237310369e-06,2.57677824894753e-05,1.00350433101176e-05,"BACE1/DRD2/CNR1/PRKCB/GSK3B/HTR2A/LRRK2/SNCA",8
"GO:0090169","BP","GO:0090169","regulation of spindle assembly","5/173","33/21081",6.92057849651048e-06,2.64676309916049e-05,1.03075933455062e-05,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",5
"GO:0031295","BP","GO:0031295","T cell costimulation","6/173","57/21081",7.18435977882003e-06,2.74517488311208e-05,1.06908496519359e-05,"PTPN11/SRC/CSK/PIK3CA/AKT1/DPP4",6
"GO:0030258","BP","GO:0030258","lipid modification","12/173","300/21081",7.32882720444305e-06,2.79786044848864e-05,1.08960290966893e-05,"PPARA/FABP1/ALOX5/ALOX5/CNR1/PPARG/AGTR1/MTOR/PIK3CA/PIK3CG/AKT1/MAPK14",12
"GO:0043518","BP","GO:0043518","negative regulation of DNA damage response, signal transduction by p53 class mediator","4/173","16/21081",7.38167688629983e-06,2.81298162241148e-05,1.09549172199796e-05,"MDM2/MIF/MIF/SIRT1",4
"GO:0090042","BP","GO:0090042","tubulin deacetylation","4/173","16/21081",7.38167688629983e-06,2.81298162241148e-05,1.09549172199796e-05,"MAPT/MAPT/MAPT/EP300",4
"GO:0070665","BP","GO:0070665","positive regulation of leukocyte proliferation","10/173","204/21081",7.46724091797912e-06,2.84062589899515e-05,1.1062575499425e-05,"MAPK3/IL6/MAPK1/TLR4/PTK2/MIF/MIF/STAT5B/CD38/IL2",10
"GO:0002753","BP","GO:0002753","cytoplasmic pattern recognition receptor signaling pathway","7/173","87/21081",7.46759032520025e-06,2.84062589899515e-05,1.1062575499425e-05,"XIAP/TLR4/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",7
"GO:1903169","BP","GO:1903169","regulation of calcium ion transmembrane transport","9/173","161/21081",7.51943164426027e-06,2.85778757213434e-05,1.11294101730319e-05,"G6PD/DRD2/DRD3/PIK3CG/NOS1/SNCA/F2/ABL1/PSEN2",9
"GO:0030148","BP","GO:0030148","sphingolipid biosynthetic process","8/173","123/21081",8.08046092799117e-06,3.06826438633016e-05,1.19490941901154e-05,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0043270","BP","GO:0043270","positive regulation of ion transport","12/173","303/21081",8.103139144993e-06,3.07412841313172e-05,1.19719311427904e-05,"G6PD/DRD2/AKT1/NOS1/MIF/MIF/SNCA/F2/ABL1/CFTR/CETP/PSEN1",12
"GO:1902850","BP","GO:1902850","microtubule cytoskeleton organization involved in mitosis","9/173","163/21081",8.31003713152837e-06,3.14980800819483e-05,1.22666588767197e-05,"XIAP/CHEK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/RHOA/VCP",9
"GO:0032984","BP","GO:0032984","protein-containing complex disassembly","13/173","358/21081",8.59814806021441e-06,3.2561079418762e-05,1.26806349100826e-05,"IGF1R/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GSK3B/INSR/PPP1CA/VCP",13
"GO:0001776","BP","GO:0001776","leukocyte homeostasis","7/173","89/21081",8.68526326029498e-06,3.28324587126275e-05,1.27863212635172e-05,"IL6/AKT1/MIF/MIF/STAT5B/ABL1/IL2",7
"GO:0055021","BP","GO:0055021","regulation of cardiac muscle tissue growth","7/173","89/21081",8.68526326029498e-06,3.28324587126275e-05,1.27863212635172e-05,"G6PD/PPARA/MTOR/MAPK1/PIM1/MAPK14/CDK1",7
"GO:0031294","BP","GO:0031294","lymphocyte costimulation","6/173","59/21081",8.80038687504861e-06,3.32085646821328e-05,1.29327925283504e-05,"PTPN11/SRC/CSK/PIK3CA/AKT1/DPP4",6
"GO:0043124","BP","GO:0043124","negative regulation of I-kappaB kinase/NF-kappaB signaling","6/173","59/21081",8.80038687504861e-06,3.32085646821328e-05,1.29327925283504e-05,"NR1H4/ESR1/RORA/RHOA/SIRT1/ABL1",6
"GO:0000082","BP","GO:0000082","G1/S transition of mitotic cell cycle","12/173","306/21081",8.94833632304023e-06,3.37368953297231e-05,1.31385463968797e-05,"TERT/MDM2/CDK2/PRMT1/CHEK2/CDK4/WEE1/AKT1/EGFR/CCND1/CDK1/EP300",12
"GO:0002696","BP","GO:0002696","positive regulation of leukocyte activation","15/173","474/21081",9.02526423468032e-06,3.39967621747843e-05,1.32397493252309e-05,"PTPN11/IL6/SRC/CSK/PIK3CA/AKT1/TLR4/LRRK2/MIF/MIF/RHOA/STAT5B/CD38/DPP4/IL2",15
"GO:0048145","BP","GO:0048145","regulation of fibroblast proliferation","7/173","90/21081",9.35324085570335e-06,3.5169841058304e-05,1.36965949000146e-05,"ESR1/PPARG/CDK4/CCNA2/EGFR/MIF/MIF",7
"GO:0050818","BP","GO:0050818","regulation of coagulation","7/173","90/21081",9.35324085570335e-06,3.5169841058304e-05,1.36965949000146e-05,"PLG/SERPINE1/PRKCA/NOS3/TLR4/F2/PSEN1",7
"GO:0071380","BP","GO:0071380","cellular response to prostaglandin E stimulus","4/173","17/21081",9.59121471043797e-06,3.60009463822005e-05,1.4020261786134e-05,"PPARG/AKT1/ACACA/ACACA",4
"GO:1904251","BP","GO:1904251","regulation of bile acid metabolic process","4/173","17/21081",9.59121471043797e-06,3.60009463822005e-05,1.4020261786134e-05,"NR1H4/CES1/CES1/SIRT1",4
"GO:0031099","BP","GO:0031099","regeneration","10/173","210/21081",9.62871881443391e-06,3.6109820161103e-05,1.40626617515586e-05,"PLG/PPARG/IL6/CSNK2A2/CDK4/CCNA2/EGFR/CCND1/CDK1/C5AR1",10
"GO:0045454","BP","GO:0045454","cell redox homeostasis","6/173","60/21081",9.71216841582407e-06,3.63906557308964e-05,1.41720307710716e-05,"NOS2/NQO1/NOS3/NOS1/GSR/MPO",6
"GO:0042692","BP","GO:0042692","muscle cell differentiation","14/173","419/21081",9.8889472657669e-06,3.70203849623291e-05,1.44172734540093e-05,"G6PD/PPARA/RORA/MDM2/MTOR/CHUK/AKT1/NOS1/HDAC4/SIRT1/ABL1/MAPK14/NOX4/CDK1",14
"GO:0048144","BP","GO:0048144","fibroblast proliferation","7/173","91/21081",1.00632713496078e-05,3.76398239123974e-05,1.46585086745584e-05,"ESR1/PPARG/CDK4/CCNA2/EGFR/MIF/MIF",7
"GO:0002822","BP","GO:0002822","regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains","10/173","212/21081",1.04601492723493e-05,3.90898630239333e-05,1.52232140500237e-05,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/IL2",10
"GO:0000075","BP","GO:0000075","cell cycle checkpoint","11/173","260/21081",1.05309148479617e-05,3.93197339094811e-05,1.53127353075533e-05,"PTPN11/BCL2L1/MDM2/CDK2/PRMT1/CHEK2/WEE1/CCND1/MAPK14/CDK1/EP300",11
"GO:0042743","BP","GO:0042743","hydrogen peroxide metabolic process","6/173","61/21081",1.06989370887787e-05,3.99120137754354e-05,1.55433936542306e-05,"EGFR/SNCA/MMP3/MPO/MAOB/STAT3",6
"GO:0014046","BP","GO:0014046","dopamine secretion","5/173","36/21081",1.07762220695862e-05,3.99547710066945e-05,1.55600450935883e-05,"DRD2/CNR1/DRD3/HTR2A/SNCA",5
"GO:0014059","BP","GO:0014059","regulation of dopamine secretion","5/173","36/21081",1.07762220695862e-05,3.99547710066945e-05,1.55600450935883e-05,"DRD2/CNR1/DRD3/HTR2A/SNCA",5
"GO:0014072","BP","GO:0014072","response to isoquinoline alkaloid","5/173","36/21081",1.07762220695862e-05,3.99547710066945e-05,1.55600450935883e-05,"DRD2/CNR1/MDM2/DRD3/MTOR",5
"GO:0042026","BP","GO:0042026","protein refolding","5/173","36/21081",1.07762220695862e-05,3.99547710066945e-05,1.55600450935883e-05,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",5
"GO:0043278","BP","GO:0043278","response to morphine","5/173","36/21081",1.07762220695862e-05,3.99547710066945e-05,1.55600450935883e-05,"DRD2/CNR1/MDM2/DRD3/MTOR",5
"GO:0050482","BP","GO:0050482","arachidonic acid secretion","5/173","36/21081",1.07762220695862e-05,3.99547710066945e-05,1.55600450935883e-05,"DRD2/DRD3/MIF/MIF/ACE",5
"GO:1903963","BP","GO:1903963","arachidonate transport","5/173","36/21081",1.07762220695862e-05,3.99547710066945e-05,1.55600450935883e-05,"DRD2/DRD3/MIF/MIF/ACE",5
"GO:0014910","BP","GO:0014910","regulation of smooth muscle cell migration","7/173","92/21081",1.08174099733003e-05,4.00725152367508e-05,1.56058995806251e-05,"SERPINE1/TERT/MDM2/SRC/HDAC4/ACE/NOX4",7
"GO:0098732","BP","GO:0098732","macromolecule deacylation","8/173","128/21081",1.08348868314151e-05,4.01022945528594e-05,1.56174968815189e-05,"MAPK8/LRRK2/HDAC4/SIRT1/MAPT/MAPT/MAPT/EP300",8
"GO:0051251","BP","GO:0051251","positive regulation of lymphocyte activation","14/173","423/21081",1.1003245190804e-05,4.06899815628599e-05,1.5846366579583e-05,"PTPN11/IL6/SRC/CSK/PIK3CA/AKT1/TLR4/MIF/MIF/RHOA/STAT5B/CD38/DPP4/IL2",14
"GO:0006720","BP","GO:0006720","isoprenoid metabolic process","9/173","169/21081",1.11226119204374e-05,4.10956330869029e-05,1.60043441088582e-05,"AKR1B10/HMGCR/SRD5A1/TTR/CYP26A1/EGFR/AKR1B1/AKR1C1/CYP1B1",9
"GO:0043161","BP","GO:0043161","proteasome-mediated ubiquitin-dependent protein catabolic process","15/173","483/21081",1.12748310375422e-05,4.16218567146107e-05,1.62092774164492e-05,"MDM2/GSK3B/CDK2/AKT1/LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SIRT1/CDK1/OGT/VCP/PSEN1",15
"GO:1903901","BP","GO:1903901","negative regulation of viral life cycle","8/173","129/21081",1.14713502246119e-05,4.23105617225487e-05,1.64774877129843e-05,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0010676","BP","GO:0010676","positive regulation of cellular carbohydrate metabolic process","6/173","62/21081",1.17652704408282e-05,4.33570113643358e-05,1.68850186086474e-05,"PPARA/SRC/AKT1/INSR/SNCA/SIRT1",6
"GO:0034620","BP","GO:0034620","cellular response to unfolded protein","9/173","171/21081",1.22247654919998e-05,4.50112899267825e-05,1.75292632978415e-05,"CCND1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/CXCL8/VCP/EP300",9
"GO:0002523","BP","GO:0002523","leukocyte migration involved in inflammatory response","4/173","18/21081",1.22526986851316e-05,4.50360871220796e-05,1.75389203542404e-05,"ALOX5/ALOX5/ELANE/ELANE",4
"GO:0048311","BP","GO:0048311","mitochondrion distribution","4/173","18/21081",1.22526986851316e-05,4.50360871220796e-05,1.75389203542404e-05,"LRRK2/MAPT/MAPT/MAPT",4
"GO:0034405","BP","GO:0034405","response to fluid shear stress","5/173","37/21081",1.23776370031956e-05,4.5455989305599e-05,1.77024476814115e-05,"SREBF2/PTGS2/SRC/NOS3/AKT1",5
"GO:0051952","BP","GO:0051952","regulation of amine transport","7/173","95/21081",1.33660909833544e-05,4.90436274510127e-05,1.90996227850496e-05,"DRD2/CNR1/DRD3/HTR2A/CHRNA3/SNCA/PSEN1",7
"GO:0016202","BP","GO:0016202","regulation of striated muscle tissue development","9/173","173/21081",1.34188032327749e-05,4.91945599103199e-05,1.91584021451544e-05,"G6PD/PPARA/HMGCR/MTOR/MAPK1/PIM1/HDAC4/MAPK14/CDK1",9
"GO:0006936","BP","GO:0006936","muscle contraction","13/173","374/21081",1.36839812733999e-05,5.01234796816174e-05,1.95201620342873e-05,"DRD2/PTGS2/TACR1/HTR2A/MTOR/PIK3CA/PIK3CG/CHUK/CHRNA3/NOS1/HDAC4/RHOA/CD38",13
"GO:0046486","BP","GO:0046486","glycerolipid metabolic process","15/173","492/21081",1.40097321927488e-05,5.12724824177344e-05,1.99676313586302e-05,"NR1H4/FABP4/FABP5/FABP1/PTPN11/NR1H3/NR1H2/HTR2A/CSNK2A1/CSNK2A2/PIK3CA/PIK3CG/SIRT1/MGLL/CETP",15
"GO:0090303","BP","GO:0090303","positive regulation of wound healing","6/173","64/21081",1.41558460740841e-05,5.17290309511718e-05,2.01454302944946e-05,"PLG/SERPINE1/MTOR/TLR4/PTK2/F2",6
"GO:0019433","BP","GO:0019433","triglyceride catabolic process","5/173","38/21081",1.41588286646771e-05,5.17290309511718e-05,2.01454302944946e-05,"FABP4/FABP5/FABP1/PIK3CG/MGLL",5
"GO:0060420","BP","GO:0060420","regulation of heart growth","7/173","96/21081",1.4318642017017e-05,5.22679638576506e-05,2.03553131224008e-05,"G6PD/PPARA/MTOR/MAPK1/PIM1/MAPK14/CDK1",7
"GO:0006413","BP","GO:0006413","translational initiation","10/173","220/21081",1.44363627379586e-05,5.26524508786145e-05,2.05050483163053e-05,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MTOR/PPP1CA",10
"GO:0042594","BP","GO:0042594","response to starvation","10/173","221/21081",1.50147386176289e-05,5.47149437275346e-05,2.13082685807643e-05,"PPARA/SRD5A1/MAPK3/SREBF2/MAPK8/PPARG/MTOR/MAPK1/LRRK2/SIRT1",10
"GO:0048568","BP","GO:0048568","embryonic organ development","15/173","495/21081",1.50441231646628e-05,5.47750465524012e-05,2.13316751137418e-05,"PLG/MAPK3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MAPK1/AKT1/EGFR/CXCL8/PSEN1",15
"GO:0010507","BP","GO:0010507","negative regulation of autophagy","7/173","97/21081",1.53266590435189e-05,5.57082756851257e-05,2.16951132469603e-05,"MTOR/PIK3CA/AKT1/LRRK2/PTK2/SNCA/STAT3",7
"GO:0046849","BP","GO:0046849","bone remodeling","7/173","97/21081",1.53266590435189e-05,5.57082756851257e-05,2.16951132469603e-05,"IL6/SRC/PRKCA/CSK/EGFR/NOX4/CD38",7
"GO:1901861","BP","GO:1901861","regulation of muscle tissue development","9/173","176/21081",1.53957726162012e-05,5.59116562788368e-05,2.17743180860714e-05,"G6PD/PPARA/HMGCR/MTOR/MAPK1/PIM1/HDAC4/MAPK14/CDK1",9
"GO:0002260","BP","GO:0002260","lymphocyte homeostasis","6/173","65/21081",1.54901563994766e-05,5.6110549481139e-05,2.18517753488376e-05,"AKT1/MIF/MIF/STAT5B/ABL1/IL2",6
"GO:0006977","BP","GO:0006977","DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest","6/173","65/21081",1.54901563994766e-05,5.6110549481139e-05,2.18517753488376e-05,"MDM2/CDK2/PRMT1/CHEK2/CDK1/EP300",6
"GO:0019748","BP","GO:0019748","secondary metabolic process","6/173","65/21081",1.54901563994766e-05,5.6110549481139e-05,2.18517753488376e-05,"AKR1B10/AKR1B1/AKR1C1/MC1R/TYR/CYP1B1",6
"GO:0050867","BP","GO:0050867","positive regulation of cell activation","15/173","497/21081",1.57708304218988e-05,5.70785847211653e-05,2.22287684239442e-05,"PTPN11/IL6/SRC/CSK/PIK3CA/AKT1/TLR4/LRRK2/MIF/MIF/RHOA/STAT5B/CD38/DPP4/IL2",15
"GO:0009267","BP","GO:0009267","cellular response to starvation","9/173","177/21081",1.61076119898947e-05,5.7996617229581e-05,2.25862883613237e-05,"PPARA/SRD5A1/MAPK3/SREBF2/MAPK8/MTOR/MAPK1/LRRK2/SIRT1",9
"GO:0048634","BP","GO:0048634","regulation of muscle organ development","9/173","177/21081",1.61076119898947e-05,5.7996617229581e-05,2.25862883613237e-05,"G6PD/PPARA/HMGCR/MTOR/MAPK1/PIM1/HDAC4/MAPK14/CDK1",9
"GO:0032094","BP","GO:0032094","response to food","5/173","39/21081",1.6133678880999e-05,5.7996617229581e-05,2.25862883613237e-05,"G6PD/PPARA/MTOR/AKT1/MPO",5
"GO:0032885","BP","GO:0032885","regulation of polysaccharide biosynthetic process","5/173","39/21081",1.6133678880999e-05,5.7996617229581e-05,2.25862883613237e-05,"GSK3B/MTOR/AKT1/INSR/PPP1CA",5
"GO:0042554","BP","GO:0042554","superoxide anion generation","5/173","39/21081",1.6133678880999e-05,5.7996617229581e-05,2.25862883613237e-05,"EGFR/NOX4/MAPT/MAPT/MAPT",5
"GO:0060416","BP","GO:0060416","response to growth hormone","5/173","39/21081",1.6133678880999e-05,5.7996617229581e-05,2.25862883613237e-05,"SRD5A1/AKT1/PTK2/STAT5B/STAT3",5
"GO:0070873","BP","GO:0070873","regulation of glycogen metabolic process","5/173","39/21081",1.6133678880999e-05,5.7996617229581e-05,2.25862883613237e-05,"GSK3B/MTOR/AKT1/INSR/PPP1CA",5
"GO:0071392","BP","GO:0071392","cellular response to estradiol stimulus","5/173","39/21081",1.6133678880999e-05,5.7996617229581e-05,2.25862883613237e-05,"SRD5A1/ESR1/ESR2/CCNA2/EGFR",5
"GO:0036473","BP","GO:0036473","cell death in response to oxidative stress","7/173","98/21081",1.63926387488301e-05,5.88777024884016e-05,2.29294195071948e-05,"AKT1/PARP1/TLR4/LRRK2/MMP3/SIRT1/CYP1B1",7
"GO:0072431","BP","GO:0072431","signal transduction involved in mitotic G1 DNA damage checkpoint","6/173","66/21081",1.69241728142059e-05,6.06842280907685e-05,2.36329555087112e-05,"MDM2/CDK2/PRMT1/CHEK2/CDK1/EP300",6
"GO:1902400","BP","GO:1902400","intracellular signal transduction involved in G1 DNA damage checkpoint","6/173","66/21081",1.69241728142059e-05,6.06842280907685e-05,2.36329555087112e-05,"MDM2/CDK2/PRMT1/CHEK2/CDK1/EP300",6
"GO:0006473","BP","GO:0006473","protein acetylation","10/173","225/21081",1.75323500992451e-05,6.28119355579195e-05,2.44615730505133e-05,"MAPK3/GSK3B/NOS1/SNCA/SIRT1/MAPT/MAPT/MAPT/OGT/EP300",10
"GO:0051100","BP","GO:0051100","negative regulation of binding","9/173","179/21081",1.76157180611941e-05,6.30574440118062e-05,2.45571842257768e-05,"PPARA/MAPK3/MAPK8/GSK3B/AKT1/LRRK2/ACE/PPP1CA/PSEN1",9
"GO:0016101","BP","GO:0016101","diterpenoid metabolic process","8/173","137/21081",1.77940732032515e-05,6.36422702362083e-05,2.47849398152678e-05,"AKR1B10/SRD5A1/TTR/CYP26A1/EGFR/AKR1B1/AKR1C1/CYP1B1",8
"GO:0042307","BP","GO:0042307","positive regulation of protein import into nucleus","5/173","40/21081",1.83166570243106e-05,6.534632720092e-05,2.54485702790369e-05,"PTGS2/MAPK1/MAPK14/CDK1/PSEN1",5
"GO:0055090","BP","GO:0055090","acylglycerol homeostasis","5/173","40/21081",1.83166570243106e-05,6.534632720092e-05,2.54485702790369e-05,"NR1H4/RORA/NR1H3/SIRT1/CETP",5
"GO:0070328","BP","GO:0070328","triglyceride homeostasis","5/173","40/21081",1.83166570243106e-05,6.534632720092e-05,2.54485702790369e-05,"NR1H4/RORA/NR1H3/SIRT1/CETP",5
"GO:0001961","BP","GO:0001961","positive regulation of cytokine-mediated signaling pathway","6/173","67/21081",1.84634017787957e-05,6.5814592414516e-05,2.56309321761453e-05,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/MMP12",6
"GO:0043500","BP","GO:0043500","muscle adaptation","8/173","138/21081",1.875852053301e-05,6.6810522837183e-05,2.60187887924222e-05,"G6PD/PPARA/PRKCA/MTOR/NOS3/PARP1/HDAC4/PTK2",8
"GO:0008406","BP","GO:0008406","gonad development","10/173","227/21081",1.89217973554311e-05,6.73356088469236e-05,2.62232790643901e-05,"CYP19A1/SRD5A1/ESR1/BCL2L1/SRC/NOS3/CCND1/INSR/SIRT1/STAT5B",10
"GO:0070663","BP","GO:0070663","regulation of leukocyte proliferation","12/173","330/21081",1.89925765318413e-05,6.7530926932045e-05,2.62993440282357e-05,"MAPK3/IDO1/IL6/ERBB2/MAPK1/TLR4/PTK2/MIF/MIF/STAT5B/CD38/IL2",12
"GO:0001991","BP","GO:0001991","regulation of systemic arterial blood pressure by circulatory renin-angiotensin","4/173","20/21081",1.91528509346561e-05,6.80438659041418e-05,2.64991037399044e-05,"CES1/CES1/ACE/CTSG",4
"GO:0051170","BP","GO:0051170","import into nucleus","9/173","181/21081",1.92423986380812e-05,6.83048887328379e-05,2.66007568562315e-05,"PTGS2/MAPK1/AKT1/LRRK2/STAT3/MAPK14/CDK1/MMP12/PSEN1",9
"GO:0002706","BP","GO:0002706","regulation of lymphocyte mediated immunity","11/173","278/21081",1.9645572610932e-05,6.96778280666529e-05,2.71354363802699e-05,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/STAT5B/IL2",11
"GO:0072413","BP","GO:0072413","signal transduction involved in mitotic cell cycle checkpoint","6/173","68/21081",2.01135432490459e-05,7.11594048835937e-05,2.77124238463563e-05,"MDM2/CDK2/PRMT1/CHEK2/CDK1/EP300",6
"GO:1902402","BP","GO:1902402","signal transduction involved in mitotic DNA damage checkpoint","6/173","68/21081",2.01135432490459e-05,7.11594048835937e-05,2.77124238463563e-05,"MDM2/CDK2/PRMT1/CHEK2/CDK1/EP300",6
"GO:1902403","BP","GO:1902403","signal transduction involved in mitotic DNA integrity checkpoint","6/173","68/21081",2.01135432490459e-05,7.11594048835937e-05,2.77124238463563e-05,"MDM2/CDK2/PRMT1/CHEK2/CDK1/EP300",6
"GO:0033044","BP","GO:0033044","regulation of chromosome organization","13/173","389/21081",2.06866810986265e-05,7.31262129684394e-05,2.84783804948252e-05,"MAPK3/MAPK8/SRC/MAPK1/PARP1/NOS1/LRRK2/SNCA/SIRT1/MAPT/MAPT/MAPT/OGT",13
"GO:0007020","BP","GO:0007020","microtubule nucleation","5/173","41/21081",2.07228218551616e-05,7.31322841051343e-05,2.84807448472758e-05,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",5
"GO:0046326","BP","GO:0046326","positive regulation of glucose import","5/173","41/21081",2.07228218551616e-05,7.31322841051343e-05,2.84807448472758e-05,"PTPN11/TERT/AKT1/INSR/MAPK14",5
"GO:0051225","BP","GO:0051225","spindle assembly","8/173","140/21081",2.08195674784283e-05,7.34127321293293e-05,2.8589962940458e-05,"XIAP/CHEK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/RHOA",8
"GO:0007187","BP","GO:0007187","G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger","11/173","280/21081",2.09903435877227e-05,7.39535405507742e-05,2.88005761716855e-05,"DRD2/CNR1/DRD3/PRKCA/HTR1A/HTR2A/NOS1/HTR4/MC1R/GLP1R/MTNR1A",11
"GO:0010634","BP","GO:0010634","positive regulation of epithelial cell migration","9/173","184/21081",2.19212667336746e-05,7.71693971428196e-05,3.00529641175044e-05,"PTGS2/SRC/PRKCA/MTOR/NOS3/AKT1/MMP9/SIRT1/ABL1",9
"GO:0070588","BP","GO:0070588","calcium ion transmembrane transport","12/173","335/21081",2.20262698533025e-05,7.74748514955981e-05,3.01719207122618e-05,"G6PD/DRD2/DRD3/HTR2A/PIK3CG/NOS1/SNCA/F2/ABL1/PSEN2/CACNA1B/PSEN1",12
"GO:0015837","BP","GO:0015837","amine transport","7/173","103/21081",2.26848836878771e-05,7.97254514390319e-05,3.10483976817228e-05,"DRD2/CNR1/DRD3/HTR2A/CHRNA3/SNCA/PSEN1",7
"GO:0002377","BP","GO:0002377","immunoglobulin production","10/173","232/21081",2.28164121133345e-05,8.01214339417839e-05,3.12026096930508e-05,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/IL2",10
"GO:0051052","BP","GO:0051052","regulation of DNA metabolic process","13/173","393/21081",2.30176421091656e-05,8.0761322313662e-05,3.14518087666638e-05,"MAPK3/PPARG/IL6/SRC/CDK2/PIK3CA/MAPK1/AKT1/PARP1/EGFR/SIRT1/NOX4/IL2",13
"GO:0071621","BP","GO:0071621","granulocyte chemotaxis","8/173","142/21081",2.30674176744966e-05,8.08691895205744e-05,3.14938167312044e-05,"MAPK3/PIK3CG/MAPK1/PTK2/CXCL8/MAPK14/DPP4/C5AR1",8
"GO:0051258","BP","GO:0051258","protein polymerization","12/173","337/21081",2.335317479466e-05,8.16528612214376e-05,3.17990109970395e-05,"MTOR/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SNCA/RHOA/ABL1/MAPT/MAPT/MAPT",12
"GO:0010907","BP","GO:0010907","positive regulation of glucose metabolic process","5/173","42/21081",2.33678228395547e-05,8.16528612214376e-05,3.17990109970395e-05,"PPARA/SRC/AKT1/INSR/SIRT1",5
"GO:0042133","BP","GO:0042133","neurotransmitter metabolic process","5/173","42/21081",2.33678228395547e-05,8.16528612214376e-05,3.17990109970395e-05,"SLC6A3/SLC6A3/MAOA/NOS1/MAOB",5
"GO:0060236","BP","GO:0060236","regulation of mitotic spindle organization","5/173","42/21081",2.33678228395547e-05,8.16528612214376e-05,3.17990109970395e-05,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",5
"GO:0002363","BP","GO:0002363","alpha-beta T cell lineage commitment","4/173","21/21081",2.35082041498401e-05,8.17400650021854e-05,3.18329717663439e-05,"IL6/MTOR/RHOA/STAT3",4
"GO:0010042","BP","GO:0010042","response to manganese ion","4/173","21/21081",2.35082041498401e-05,8.17400650021854e-05,3.18329717663439e-05,"BACE1/PTGS2/LRRK2/APP",4
"GO:0032930","BP","GO:0032930","positive regulation of superoxide anion generation","4/173","21/21081",2.35082041498401e-05,8.17400650021854e-05,3.18329717663439e-05,"EGFR/MAPT/MAPT/MAPT",4
"GO:0042053","BP","GO:0042053","regulation of dopamine metabolic process","4/173","21/21081",2.35082041498401e-05,8.17400650021854e-05,3.18329717663439e-05,"SLC6A3/SLC6A3/HTR1A/MAOB",4
"GO:0042069","BP","GO:0042069","regulation of catecholamine metabolic process","4/173","21/21081",2.35082041498401e-05,8.17400650021854e-05,3.18329717663439e-05,"SLC6A3/SLC6A3/HTR1A/MAOB",4
"GO:1900543","BP","GO:1900543","negative regulation of purine nucleotide metabolic process","4/173","21/21081",2.35082041498401e-05,8.17400650021854e-05,3.18329717663439e-05,"PPARA/PARP1/HDAC4/STAT3",4
"GO:0045137","BP","GO:0045137","development of primary sexual characteristics","10/173","233/21081",2.36728088136931e-05,8.22451060093067e-05,3.20296556828554e-05,"CYP19A1/SRD5A1/ESR1/BCL2L1/SRC/NOS3/CCND1/INSR/SIRT1/STAT5B",10
"GO:0046622","BP","GO:0046622","positive regulation of organ growth","6/173","70/21081",2.37703452582907e-05,8.25165008190173e-05,3.21353480788037e-05,"MTOR/MAPK1/PIM1/AKT1/MAPK14/CDK1",6
"GO:0034103","BP","GO:0034103","regulation of tissue remodeling","7/173","104/21081",2.41555179110281e-05,8.37851392685376e-05,3.26294085122546e-05,"IL6/SRC/PRKCA/CSK/EGFR/CD38/IL2",7
"GO:0016236","BP","GO:0016236","macroautophagy","12/173","340/21081",2.54740893064916e-05,8.82866276209486e-05,3.43824747916243e-05,"MAPK3/MAPK8/SRC/CSNK2A1/CSNK2A2/MTOR/PIK3CA/AKT1/LRRK2/SIRT1/VCP/PSEN1",12
"GO:0007589","BP","GO:0007589","body fluid secretion","7/173","105/21081",2.57038406887796e-05,8.89378005591406e-05,3.46360685434267e-05,"SLC6A3/SLC6A3/NR1H3/NR1H2/XDH/CCND1/STAT5B",7
"GO:0014909","BP","GO:0014909","smooth muscle cell migration","7/173","105/21081",2.57038406887796e-05,8.89378005591406e-05,3.46360685434267e-05,"SERPINE1/TERT/MDM2/SRC/HDAC4/ACE/NOX4",7
"GO:0042698","BP","GO:0042698","ovulation cycle","6/173","71/21081",2.57893942828599e-05,8.90887287055867e-05,3.46948462239245e-05,"ESR1/SRC/NOS3/EGFR/SIRT1/STAT5B",6
"GO:0071479","BP","GO:0071479","cellular response to ionizing radiation","6/173","71/21081",2.57893942828599e-05,8.90887287055867e-05,3.46948462239245e-05,"BCL2L1/MDM2/CHEK2/SIRT1/MAPK14/NOX4",6
"GO:0000077","BP","GO:0000077","DNA damage checkpoint","9/173","188/21081",2.59811762624314e-05,8.95328612644533e-05,3.48678098642952e-05,"PTPN11/MDM2/CDK2/PRMT1/CHEK2/CCND1/MAPK14/CDK1/EP300",9
"GO:0006475","BP","GO:0006475","internal protein amino acid acetylation","9/173","188/21081",2.59811762624314e-05,8.95328612644533e-05,3.48678098642952e-05,"MAPK3/NOS1/SNCA/SIRT1/MAPT/MAPT/MAPT/OGT/EP300",9
"GO:0006665","BP","GO:0006665","sphingolipid metabolic process","9/173","188/21081",2.59811762624314e-05,8.95328612644533e-05,3.48678098642952e-05,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PPP2CA",9
"GO:0010737","BP","GO:0010737","protein kinase A signaling","5/173","43/21081",2.62679009562621e-05,9.00825755957688e-05,3.50818914262299e-05,"PDE4A/LRRK2/MIF/MIF/MC1R",5
"GO:0030890","BP","GO:0030890","positive regulation of B cell proliferation","5/173","43/21081",2.62679009562621e-05,9.00825755957688e-05,3.50818914262299e-05,"TLR4/MIF/MIF/CD38/IL2",5
"GO:0033120","BP","GO:0033120","positive regulation of RNA splicing","5/173","43/21081",2.62679009562621e-05,9.00825755957688e-05,3.50818914262299e-05,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",5
"GO:0051085","BP","GO:0051085","chaperone cofactor-dependent protein refolding","5/173","43/21081",2.62679009562621e-05,9.00825755957688e-05,3.50818914262299e-05,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",5
"GO:0071364","BP","GO:0071364","cellular response to epidermal growth factor stimulus","5/173","43/21081",2.62679009562621e-05,9.00825755957688e-05,3.50818914262299e-05,"PTPN11/ERBB2/AKT1/EGFR/STAT5B",5
"GO:1904591","BP","GO:1904591","positive regulation of protein import","5/173","43/21081",2.62679009562621e-05,9.00825755957688e-05,3.50818914262299e-05,"PTGS2/MAPK1/MAPK14/CDK1/PSEN1",5
"GO:0002460","BP","GO:0002460","adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains","14/173","458/21081",2.65741650389578e-05,9.10593768149451e-05,3.54622983372171e-05,"RORA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/MTOR/TLR4/STAT3/IL2",14
"GO:0007548","BP","GO:0007548","sex differentiation","11/173","288/21081",2.71988159056597e-05,9.31247129598292e-05,3.62666258990602e-05,"CYP19A1/SRD5A1/PTPN11/ESR1/BCL2L1/SRC/NOS3/CCND1/INSR/SIRT1/STAT5B",11
"GO:0046632","BP","GO:0046632","alpha-beta T cell differentiation","7/173","106/21081",2.73330054704281e-05,9.35088085699267e-05,3.64162086613382e-05,"RORA/IL6/MTOR/RHOA/ABL1/STAT3/IL2",7
"GO:0032890","BP","GO:0032890","regulation of organic acid transport","6/173","72/21081",2.79441371586592e-05,9.54458511150668e-05,3.71705733740162e-05,"CES1/CES1/AKT1/MIF/MIF/PSEN1",6
"GO:0061077","BP","GO:0061077","chaperone-mediated protein folding","6/173","72/21081",2.79441371586592e-05,9.54458511150668e-05,3.71705733740162e-05,"CSNK2A1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",6
"GO:0045980","BP","GO:0045980","negative regulation of nucleotide metabolic process","4/173","22/21081",2.85486741413632e-05,9.74323826720098e-05,3.79442111606197e-05,"PPARA/PARP1/HDAC4/STAT3",4
"GO:0006643","BP","GO:0006643","membrane lipid metabolic process","10/173","239/21081",2.94133167258872e-05,0.000100302714902323,3.90620375881513e-05,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CYP1B1/PPP2CA",10
"GO:0033627","BP","GO:0033627","cell adhesion mediated by integrin","6/173","73/21081",3.0241275537345e-05,0.00010304344808194,4.01293927697686e-05,"PTPN11/SERPINE1/PIK3CG/PTK2/CYP1B1/DPP4",6
"GO:0006721","BP","GO:0006721","terpenoid metabolic process","8/173","149/21081",3.26041025309235e-05,0.000111005474081646,4.32301359468722e-05,"AKR1B10/SRD5A1/TTR/CYP26A1/EGFR/AKR1B1/AKR1C1/CYP1B1",8
"GO:0045600","BP","GO:0045600","positive regulation of fat cell differentiation","6/173","74/21081",3.2687717683589e-05,0.000111201050790688,4.33063016296e-05,"PPARG/PTGS2/HTR2A/PIM1/AKT1/MAPK14",6
"GO:0071379","BP","GO:0071379","cellular response to prostaglandin stimulus","4/173","23/21081",3.43381708153798e-05,0.000116722310235639,4.54565090709702e-05,"PPARG/AKT1/ACACA/ACACA",4
"GO:0008361","BP","GO:0008361","regulation of cell size","9/173","195/21081",3.46258813793077e-05,0.00011760621101573,4.58007366976076e-05,"GSK3B/MTOR/CDK4/AKT1/RHOA/ABL1/MAPT/MAPT/MAPT",9
"GO:0033143","BP","GO:0033143","regulation of intracellular steroid hormone receptor signaling pathway","6/173","75/21081",3.52905803734251e-05,0.000119768111826424,4.66426705456737e-05,"ESR1/SRC/PARP1/RHOA/SIRT1/EP300",6
"GO:0010212","BP","GO:0010212","response to ionizing radiation","8/173","151/21081",3.58670568105586e-05,0.000121530402223336,4.73289795233763e-05,"BCL2L1/MDM2/CHEK2/PARP1/CCND1/SIRT1/MAPK14/NOX4",8
"GO:0048525","BP","GO:0048525","negative regulation of viral process","8/173","151/21081",3.58670568105586e-05,0.000121530402223336,4.73289795233763e-05,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0010677","BP","GO:0010677","negative regulation of cellular carbohydrate metabolic process","5/173","46/21081",3.66698838368544e-05,0.000124151662488282,4.83498069964648e-05,"PPARA/GSK3B/HDAC4/STAT3/EP300",5
"GO:0006939","BP","GO:0006939","smooth muscle contraction","7/173","111/21081",3.68080041402815e-05,0.000124421010017547,4.84547020964891e-05,"DRD2/PTGS2/TACR1/HTR2A/CHRNA3/RHOA/CD38",7
"GO:0019395","BP","GO:0019395","fatty acid oxidation","7/173","111/21081",3.68080041402815e-05,0.000124421010017547,4.84547020964891e-05,"PPARA/FABP1/CNR1/PPARG/MTOR/AKT1/MAPK14",7
"GO:0031570","BP","GO:0031570","DNA integrity checkpoint","9/173","198/21081",3.90150825492625e-05,0.000131776697735943,5.13193119968544e-05,"PTPN11/MDM2/CDK2/PRMT1/CHEK2/CCND1/MAPK14/CDK1/EP300",9
"GO:0005978","BP","GO:0005978","glycogen biosynthetic process","5/173","47/21081",4.07645115764857e-05,0.00013692364402252,5.33237463684089e-05,"GSK3B/MTOR/AKT1/INSR/PPP1CA",5
"GO:0009250","BP","GO:0009250","glucan biosynthetic process","5/173","47/21081",4.07645115764857e-05,0.00013692364402252,5.33237463684089e-05,"GSK3B/MTOR/AKT1/INSR/PPP1CA",5
"GO:0010828","BP","GO:0010828","positive regulation of glucose transmembrane transport","5/173","47/21081",4.07645115764857e-05,0.00013692364402252,5.33237463684089e-05,"PTPN11/TERT/AKT1/INSR/MAPK14",5
"GO:0022602","BP","GO:0022602","ovulation cycle process","5/173","47/21081",4.07645115764857e-05,0.00013692364402252,5.33237463684089e-05,"ESR1/SRC/NOS3/SIRT1/STAT5B",5
"GO:0032881","BP","GO:0032881","regulation of polysaccharide metabolic process","5/173","47/21081",4.07645115764857e-05,0.00013692364402252,5.33237463684089e-05,"GSK3B/MTOR/AKT1/INSR/PPP1CA",5
"GO:0048538","BP","GO:0048538","thymus development","5/173","47/21081",4.07645115764857e-05,0.00013692364402252,5.33237463684089e-05,"MAPK3/MAPK1/ABL1/TYR/PSEN1",5
"GO:0090224","BP","GO:0090224","regulation of spindle organization","5/173","47/21081",4.07645115764857e-05,0.00013692364402252,5.33237463684089e-05,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",5
"GO:0002689","BP","GO:0002689","negative regulation of leukocyte chemotaxis","4/173","24/21081",4.0942659153639e-05,0.000136980597436073,5.3345926389988e-05,"CYP19A1/MIF/MIF/DPP4",4
"GO:0032225","BP","GO:0032225","regulation of synaptic transmission, dopaminergic","4/173","24/21081",4.0942659153639e-05,0.000136980597436073,5.3345926389988e-05,"DRD2/PTGS2/DRD3/SNCA",4
"GO:0046628","BP","GO:0046628","positive regulation of insulin receptor signaling pathway","4/173","24/21081",4.0942659153639e-05,0.000136980597436073,5.3345926389988e-05,"NR1H4/PTPN11/SRC/SIRT1",4
"GO:0071404","BP","GO:0071404","cellular response to low-density lipoprotein particle stimulus","4/173","24/21081",4.0942659153639e-05,0.000136980597436073,5.3345926389988e-05,"CES1/CES1/SREBF2/PPARG",4
"GO:2000209","BP","GO:2000209","regulation of anoikis","4/173","24/21081",4.0942659153639e-05,0.000136980597436073,5.3345926389988e-05,"SRC/CHEK2/PIK3CA/PTK2",4
"GO:0007188","BP","GO:0007188","adenylate cyclase-modulating G protein-coupled receptor signaling pathway","10/173","249/21081",4.16347588232781e-05,0.000139186538347843,5.42050112801301e-05,"DRD2/CNR1/DRD3/PRKCA/HTR1A/NOS1/HTR4/MC1R/GLP1R/MTNR1A",10
"GO:0007093","BP","GO:0007093","mitotic cell cycle checkpoint","9/173","200/21081",4.21955187830829e-05,0.00014095028247588,5.48918864010313e-05,"BCL2L1/MDM2/CDK2/PRMT1/CHEK2/WEE1/CCND1/CDK1/EP300",9
"GO:0055024","BP","GO:0055024","regulation of cardiac muscle tissue development","7/173","114/21081",4.36843713179501e-05,0.000145809028853079,5.67840837737773e-05,"G6PD/PPARA/MTOR/MAPK1/PIM1/MAPK14/CDK1",7
"GO:1903036","BP","GO:1903036","positive regulation of response to wounding","6/173","78/21081",4.41120246545314e-05,0.000146890276455411,5.72051664386433e-05,"PLG/SERPINE1/MTOR/TLR4/PTK2/F2",6
"GO:1903201","BP","GO:1903201","regulation of oxidative stress-induced cell death","6/173","78/21081",4.41120246545314e-05,0.000146890276455411,5.72051664386433e-05,"AKT1/PARP1/TLR4/LRRK2/MMP3/SIRT1",6
"GO:1903524","BP","GO:1903524","positive regulation of blood circulation","6/173","78/21081",4.41120246545314e-05,0.000146890276455411,5.72051664386433e-05,"PTGS2/HTR2A/AKT1/EGFR/RHOA/CD38",6
"GO:0051084","BP","GO:0051084","'de novo' posttranslational protein folding","5/173","48/21081",4.52042886080379e-05,0.000150284464801991,5.85270041666102e-05,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",5
"GO:0042177","BP","GO:0042177","negative regulation of protein catabolic process","8/173","156/21081",4.52374277434095e-05,0.000150284464801991,5.85270041666102e-05,"HMGCR/NOS2/CSNK2A1/CSNK2A2/EGFR/SNCA/OGT/PSEN1",8
"GO:0044106","BP","GO:0044106","cellular amine metabolic process","8/173","156/21081",4.52374277434095e-05,0.000150284464801991,5.85270041666102e-05,"NR1H4/SLC6A3/SLC6A3/IDO1/HTR1A/NQO1/MAOA/MAOB",8
"GO:0003300","BP","GO:0003300","cardiac muscle hypertrophy","7/173","115/21081",4.61977868954822e-05,0.000153235282216162,5.96761748631398e-05,"G6PD/PPARA/PRKCA/MTOR/PARP1/HDAC4/PTK2",7
"GO:0050905","BP","GO:0050905","neuromuscular process","7/173","115/21081",4.61977868954822e-05,0.000153235282216162,5.96761748631398e-05,"SLC6A3/SLC6A3/BACE1/DRD2/DRD3/ABL1/APP",7
"GO:0072655","BP","GO:0072655","establishment of protein localization to mitochondrion","8/173","157/21081",4.73371787892597e-05,0.000156786345021781,6.10591060123719e-05,"SREBF2/MAPK8/CSNK2A2/AKT1/LRRK2/MAPT/MAPT/MAPT",8
"GO:0033555","BP","GO:0033555","multicellular organismal response to stress","6/173","79/21081",4.74159692522919e-05,0.000156786345021781,6.10591060123719e-05,"IDO1/TACR1/HTR1A/NOS1/DPP4/CACNA1B",6
"GO:0045685","BP","GO:0045685","regulation of glial cell differentiation","6/173","79/21081",4.74159692522919e-05,0.000156786345021781,6.10591060123719e-05,"PPARG/IL6/DRD3/MTOR/F2/CDK1",6
"GO:0050922","BP","GO:0050922","negative regulation of chemotaxis","6/173","79/21081",4.74159692522919e-05,0.000156786345021781,6.10591060123719e-05,"CYP19A1/MIF/MIF/DPP4/ELANE/ELANE",6
"GO:0032928","BP","GO:0032928","regulation of superoxide anion generation","4/173","25/21081",4.84300669330437e-05,0.000159518879378684,6.21232682323498e-05,"EGFR/MAPT/MAPT/MAPT",4
"GO:0034695","BP","GO:0034695","response to prostaglandin E","4/173","25/21081",4.84300669330437e-05,0.000159518879378684,6.21232682323498e-05,"PPARG/AKT1/ACACA/ACACA",4
"GO:0044321","BP","GO:0044321","response to leptin","4/173","25/21081",4.84300669330437e-05,0.000159518879378684,6.21232682323498e-05,"CCNA2/CCND1/SIRT1/STAT3",4
"GO:0051580","BP","GO:0051580","regulation of neurotransmitter uptake","4/173","25/21081",4.84300669330437e-05,0.000159518879378684,6.21232682323498e-05,"DRD2/DRD3/NOS1/SNCA",4
"GO:0051882","BP","GO:0051882","mitochondrial depolarization","4/173","25/21081",4.84300669330437e-05,0.000159518879378684,6.21232682323498e-05,"SRC/PARP1/LRRK2/ABL1",4
"GO:0035967","BP","GO:0035967","cellular response to topologically incorrect protein","9/173","204/21081",4.9217802332629e-05,0.000161987948963083,6.30848263417936e-05,"CCND1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/CXCL8/VCP/EP300",9
"GO:0032369","BP","GO:0032369","negative regulation of lipid transport","5/173","49/21081",5.00089953812041e-05,0.000164210372005206,6.39503300571486e-05,"PTPN11/NR1H3/SREBF2/NR1H2/AKT1",5
"GO:0046189","BP","GO:0046189","phenol-containing compound biosynthetic process","5/173","49/21081",5.00089953812041e-05,0.000164210372005206,6.39503300571486e-05,"SLC6A3/SLC6A3/SNCA/MC1R/TYR",5
"GO:1900274","BP","GO:1900274","regulation of phospholipase C activity","5/173","49/21081",5.00089953812041e-05,0.000164210372005206,6.39503300571486e-05,"ESR1/HTR2A/EGFR/ABL1/C5AR1",5
"GO:0008277","BP","GO:0008277","regulation of G protein-coupled receptor signaling pathway","8/173","159/21081",5.17810829082794e-05,0.000169897931488246,6.61653016312256e-05,"DRD2/DRD3/PRKCA/NOS1/SNCA/F2/CXCL8/MGLL",8
"GO:0008593","BP","GO:0008593","regulation of Notch signaling pathway","7/173","118/21081",5.44589680797949e-05,0.000178134068799883,6.93727951229185e-05,"SREBF2/SRC/NOS3/AKT1/EGFR/STAT3/EP300",7
"GO:0014812","BP","GO:0014812","muscle cell migration","7/173","118/21081",5.44589680797949e-05,0.000178134068799883,6.93727951229185e-05,"SERPINE1/TERT/MDM2/SRC/HDAC4/ACE/NOX4",7
"GO:0014897","BP","GO:0014897","striated muscle hypertrophy","7/173","118/21081",5.44589680797949e-05,0.000178134068799883,6.93727951229185e-05,"G6PD/PPARA/PRKCA/MTOR/PARP1/HDAC4/PTK2",7
"GO:0022600","BP","GO:0022600","digestive system process","7/173","118/21081",5.44589680797949e-05,0.000178134068799883,6.93727951229185e-05,"NPC1L1/FABP1/NR1H3/NR1H2/DRD3/TLR4/AKR1C1",7
"GO:0010611","BP","GO:0010611","regulation of cardiac muscle hypertrophy","6/173","81/21081",5.46178394263416e-05,0.000178516307478866,6.95216547191976e-05,"G6PD/PPARA/PRKCA/MTOR/PARP1/PTK2",6
"GO:0006986","BP","GO:0006986","response to unfolded protein","9/173","207/21081",5.51106509637333e-05,0.000179850350188097,7.004118628425e-05,"CCND1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/CXCL8/VCP/EP300",9
"GO:1903900","BP","GO:1903900","regulation of viral life cycle","9/173","207/21081",5.51106509637333e-05,0.000179850350188097,7.004118628425e-05,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CXCL8",9
"GO:0008542","BP","GO:0008542","visual learning","5/173","50/21081",5.51989965473126e-05,0.000179862374485837,7.00458690445393e-05,"HMGCR/DRD2/DRD3/MTOR/APP",5
"GO:0060324","BP","GO:0060324","face development","5/173","50/21081",5.51989965473126e-05,0.000179862374485837,7.00458690445393e-05,"MAPK3/PTPN11/MAPK1/MMP2/EP300",5
"GO:1902254","BP","GO:1902254","negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator","4/173","26/21081",5.68701944657067e-05,0.000185165866884895,7.21112689655906e-05,"MDM2/MIF/MIF/SIRT1",4
"GO:0055017","BP","GO:0055017","cardiac muscle tissue growth","7/173","119/21081",5.7467245185077e-05,0.000186966558033225,7.28125327887007e-05,"G6PD/PPARA/MTOR/MAPK1/PIM1/MAPK14/CDK1",7
"GO:0050863","BP","GO:0050863","regulation of T cell activation","13/173","430/21081",5.80660653996948e-05,0.000188770246276437,7.35149638048727e-05,"PTPN11/IDO1/IL6/SRC/ERBB2/CSK/PIK3CA/AKT1/RHOA/STAT5B/ABL1/DPP4/IL2",13
"GO:0072401","BP","GO:0072401","signal transduction involved in DNA integrity checkpoint","6/173","82/21081",5.85327904436089e-05,0.000189996811760805,7.39926392805703e-05,"MDM2/CDK2/PRMT1/CHEK2/CDK1/EP300",6
"GO:0072422","BP","GO:0072422","signal transduction involved in DNA damage checkpoint","6/173","82/21081",5.85327904436089e-05,0.000189996811760805,7.39926392805703e-05,"MDM2/CDK2/PRMT1/CHEK2/CDK1/EP300",6
"GO:0070585","BP","GO:0070585","protein localization to mitochondrion","8/173","162/21081",5.90951521560201e-05,0.000191675802680099,7.46465079865517e-05,"SREBF2/MAPK8/CSNK2A2/AKT1/LRRK2/MAPT/MAPT/MAPT",8
"GO:0099504","BP","GO:0099504","synaptic vesicle cycle","9/173","209/21081",5.93611649077712e-05,0.000192391754151884,7.4925329186251e-05,"BACE1/DRD2/CNR1/PRKCB/GSK3B/HTR2A/LRRK2/SNCA/PSEN1",9
"GO:0014896","BP","GO:0014896","muscle hypertrophy","7/173","120/21081",6.06101660672344e-05,0.000196140590723289,7.63852816432377e-05,"G6PD/PPARA/PRKCA/MTOR/PARP1/HDAC4/PTK2",7
"GO:0071887","BP","GO:0071887","leukocyte apoptotic process","7/173","120/21081",6.06101660672344e-05,0.000196140590723289,7.63852816432377e-05,"IDO1/IL6/AKT1/MIF/MIF/SIRT1/IL2",7
"GO:0008206","BP","GO:0008206","bile acid metabolic process","5/173","51/21081",6.07952382406576e-05,0.000196589777233298,7.65602135018135e-05,"NR1H4/CES1/CES1/AKR1C1/SIRT1",5
"GO:0017038","BP","GO:0017038","protein import","9/173","210/21081",6.15879908522492e-05,0.000199001804662515,7.74995570300066e-05,"PTGS2/MAPK1/AKT1/LRRK2/STAT3/MAPK14/CDK1/MMP12/PSEN1",9
"GO:0010760","BP","GO:0010760","negative regulation of macrophage chemotaxis","3/173","10/21081",6.24763293540994e-05,0.000200955278898992,7.8260320924853e-05,"CYP19A1/MIF/MIF",3
"GO:0030647","BP","GO:0030647","aminoglycoside antibiotic metabolic process","3/173","10/21081",6.24763293540994e-05,0.000200955278898992,7.8260320924853e-05,"AKR1B10/AKR1B1/AKR1C1",3
"GO:0031284","BP","GO:0031284","positive regulation of guanylate cyclase activity","3/173","10/21081",6.24763293540994e-05,0.000200955278898992,7.8260320924853e-05,"NOS2/NOS3/NOS1",3
"GO:0031666","BP","GO:0031666","positive regulation of lipopolysaccharide-mediated signaling pathway","3/173","10/21081",6.24763293540994e-05,0.000200955278898992,7.8260320924853e-05,"PRKCA/MIF/MIF",3
"GO:0072386","BP","GO:0072386","plus-end-directed organelle transport along microtubule","3/173","10/21081",6.24763293540994e-05,0.000200955278898992,7.8260320924853e-05,"MAPT/MAPT/MAPT",3
"GO:1990535","BP","GO:1990535","neuron projection maintenance","3/173","10/21081",6.24763293540994e-05,0.000200955278898992,7.8260320924853e-05,"INSR/APP/PSEN1",3
"GO:0043536","BP","GO:0043536","positive regulation of blood vessel endothelial cell migration","6/173","83/21081",6.26688026634365e-05,0.000201269646649238,7.83827487662984e-05,"PTGS2/PRKCA/NOS3/AKT1/SIRT1/ABL1",6
"GO:0072395","BP","GO:0072395","signal transduction involved in cell cycle checkpoint","6/173","83/21081",6.26688026634365e-05,0.000201269646649238,7.83827487662984e-05,"MDM2/CDK2/PRMT1/CHEK2/CDK1/EP300",6
"GO:0006164","BP","GO:0006164","purine nucleotide biosynthetic process","9/173","211/21081",6.38848169980507e-05,0.000205020081136494,7.98433235179963e-05,"NOS2/NOS3/PARP1/NOS1/STAT3/FASN/ACACA/ACACA/VCP",9
"GO:0032943","BP","GO:0032943","mononuclear cell proliferation","12/173","375/21081",6.56795593719875e-05,0.000210620715299302,8.20244427668436e-05,"IDO1/IL6/ERBB2/PIK3CG/TLR4/MIF/MIF/ACE/STAT5B/ABL1/CD38/IL2",12
"GO:0007051","BP","GO:0007051","spindle organization","9/173","212/21081",6.62533983257911e-05,0.000211921674630974,8.25310902924257e-05,"XIAP/CHEK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/RHOA/VCP",9
"GO:0018904","BP","GO:0018904","ether metabolic process","4/173","27/21081",6.6334626326005e-05,0.000211921674630974,8.25310902924257e-05,"ALOX5/ALOX5/EPHX1/FASN",4
"GO:0070633","BP","GO:0070633","transepithelial transport","4/173","27/21081",6.6334626326005e-05,0.000211921674630974,8.25310902924257e-05,"ABCC1/ABCC1/ABCG2/CFTR",4
"GO:0072539","BP","GO:0072539","T-helper 17 cell differentiation","4/173","27/21081",6.6334626326005e-05,0.000211921674630974,8.25310902924257e-05,"RORA/IL6/STAT3/IL2",4
"GO:1903649","BP","GO:1903649","regulation of cytoplasmic transport","4/173","27/21081",6.6334626326005e-05,0.000211921674630974,8.25310902924257e-05,"MAPK3/SRC/MAPK1/LRRK2",4
"GO:0006458","BP","GO:0006458","'de novo' protein folding","5/173","52/21081",6.68192449833403e-05,0.00021298947631974,8.29469365608331e-05,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",5
"GO:0030225","BP","GO:0030225","macrophage differentiation","5/173","52/21081",6.68192449833403e-05,0.00021298947631974,8.29469365608331e-05,"PRKCA/PARP1/MMP9/SIRT1/APP",5
"GO:0045912","BP","GO:0045912","negative regulation of carbohydrate metabolic process","5/173","52/21081",6.68192449833403e-05,0.00021298947631974,8.29469365608331e-05,"PPARA/GSK3B/HDAC4/STAT3/EP300",5
"GO:0014743","BP","GO:0014743","regulation of muscle hypertrophy","6/173","84/21081",6.70349409865931e-05,0.000213356902061449,8.30900273849196e-05,"G6PD/PPARA/PRKCA/MTOR/PARP1/PTK2",6
"GO:0030193","BP","GO:0030193","regulation of blood coagulation","6/173","84/21081",6.70349409865931e-05,0.000213356902061449,8.30900273849196e-05,"PLG/SERPINE1/PRKCA/NOS3/TLR4/F2",6
"GO:0009308","BP","GO:0009308","amine metabolic process","8/173","165/21081",6.72494385746661e-05,0.000213719419972892,8.32312068963312e-05,"NR1H4/SLC6A3/SLC6A3/IDO1/HTR1A/NQO1/MAOA/MAOB",8
"GO:0046467","BP","GO:0046467","membrane lipid biosynthetic process","8/173","165/21081",6.72494385746661e-05,0.000213719419972892,8.32312068963312e-05,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0038093","BP","GO:0038093","Fc receptor signaling pathway","10/173","264/21081",6.79803739028939e-05,0.000215880873477874,8.40729665449998e-05,"MAPK3/MAPK8/SRC/IKBKB/PIK3CA/MAPK1/CHUK/PTK2/MAPK10/ABL1",10
"GO:0043488","BP","GO:0043488","regulation of mRNA stability","9/173","213/21081",6.86955216447546e-05,0.000217989000349934,8.48939585908999e-05,"PRKCA/MTOR/AKT1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/MAPK14",9
"GO:0097530","BP","GO:0097530","granulocyte migration","8/173","166/21081",7.0166935957899e-05,0.000222492023048592,8.66476224083403e-05,"MAPK3/PIK3CG/MAPK1/PTK2/CXCL8/MAPK14/DPP4/C5AR1",8
"GO:0007041","BP","GO:0007041","lysosomal transport","7/173","123/21081",7.08930319292612e-05,0.000224626765598382,8.7478979703127e-05,"LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/VCP",7
"GO:1900046","BP","GO:1900046","regulation of hemostasis","6/173","85/21081",7.16404931642057e-05,0.00022682597276804,8.8335442194785e-05,"PLG/SERPINE1/PRKCA/NOS3/TLR4/F2",6
"GO:0045540","BP","GO:0045540","regulation of cholesterol biosynthetic process","5/173","53/21081",7.32931162268938e-05,0.000231540855649124,9.01716131549028e-05,"HMGCR/SREBF2/FASN/ACACA/ACACA",5
"GO:0106118","BP","GO:0106118","regulation of sterol biosynthetic process","5/173","53/21081",7.32931162268938e-05,0.000231540855649124,9.01716131549028e-05,"HMGCR/SREBF2/FASN/ACACA/ACACA",5
"GO:1990090","BP","GO:1990090","cellular response to nerve growth factor stimulus","5/173","53/21081",7.32931162268938e-05,0.000231540855649124,9.01716131549028e-05,"AKT1/APP/MAPT/MAPT/MAPT",5
"GO:0050921","BP","GO:0050921","positive regulation of chemotaxis","8/173","168/21081",7.63180823100275e-05,0.000240917928480912,9.38234342624253e-05,"MAPK3/SERPINE1/IL6/MAPK1/PTK2/CXCL8/MAPK14/C5AR1",8
"GO:0034644","BP","GO:0034644","cellular response to UV","6/173","86/21081",7.64949707647825e-05,0.000241297053288464,9.39710811880109e-05,"MDM2/PTGS2/PARP1/MC1R/SIRT1/EP300",6
"GO:0002360","BP","GO:0002360","T cell lineage commitment","4/173","28/21081",7.6896645031601e-05,0.000242204480903834,9.43244711401637e-05,"IL6/MTOR/RHOA/STAT3",4
"GO:0010971","BP","GO:0010971","positive regulation of G2/M transition of mitotic cell cycle","4/173","28/21081",7.6896645031601e-05,0.000242204480903834,9.43244711401637e-05,"CDK4/CCND1/CDK1/APP",4
"GO:0030518","BP","GO:0030518","intracellular steroid hormone receptor signaling pathway","7/173","125/21081",7.85080736381522e-05,0.000247096892510006,9.62297791494544e-05,"ESR1/ESR2/SRC/PARP1/RHOA/SIRT1/EP300",7
"GO:0000186","BP","GO:0000186","activation of MAPKK activity","5/173","54/21081",8.02395225436884e-05,0.000251243722393612,9.78447267103736e-05,"MAPK3/MAPK1/LRRK2/EGFR/PSEN1",5
"GO:0014911","BP","GO:0014911","positive regulation of smooth muscle cell migration","5/173","54/21081",8.02395225436884e-05,0.000251243722393612,9.78447267103736e-05,"TERT/MDM2/SRC/HDAC4/NOX4",5
"GO:0042771","BP","GO:0042771","intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator","5/173","54/21081",8.02395225436884e-05,0.000251243722393612,9.78447267103736e-05,"CHEK2/MIF/MIF/SIRT1/EP300",5
"GO:0046461","BP","GO:0046461","neutral lipid catabolic process","5/173","54/21081",8.02395225436884e-05,0.000251243722393612,9.78447267103736e-05,"FABP4/FABP5/FABP1/PIK3CG/MGLL",5
"GO:0046464","BP","GO:0046464","acylglycerol catabolic process","5/173","54/21081",8.02395225436884e-05,0.000251243722393612,9.78447267103736e-05,"FABP4/FABP5/FABP1/PIK3CG/MGLL",5
"GO:0071320","BP","GO:0071320","cellular response to cAMP","5/173","54/21081",8.02395225436884e-05,0.000251243722393612,9.78447267103736e-05,"SRD5A1/PIK3CG/NOX4/APP/CFTR",5
"GO:1900087","BP","GO:1900087","positive regulation of G1/S transition of mitotic cell cycle","5/173","54/21081",8.02395225436884e-05,0.000251243722393612,9.78447267103736e-05,"TERT/MDM2/AKT1/EGFR/CCND1",5
"GO:0042113","BP","GO:0042113","B cell activation","11/173","325/21081",8.09963284629314e-05,0.000253426656582471,9.86948518283297e-05,"IL6/PRKCB/TLR4/HDAC4/MIF/MIF/STAT5B/ABL1/CD38/IL2/EP300",11
"GO:0001960","BP","GO:0001960","negative regulation of cytokine-mediated signaling pathway","6/173","87/21081",8.16081100566032e-05,0.000255152950427158,9.93671422555132e-05,"NR1H4/NR1H3/PPARG/IL6/NR1H2/MMP12",6
"GO:0043543","BP","GO:0043543","protein acylation","10/173","271/21081",8.44659859758667e-05,0.000263894098831954,0.00010277130801398,"MAPK3/GSK3B/NOS1/SNCA/SIRT1/MAPT/MAPT/MAPT/OGT/EP300",10
"GO:0019371","BP","GO:0019371","cyclooxygenase pathway","3/173","11/21081",8.53866619290365e-05,0.000265404481738461,0.000103359513766177,"PTGS1/PTGS2/CBR1",3
"GO:0042447","BP","GO:0042447","hormone catabolic process","3/173","11/21081",8.53866619290365e-05,0.000265404481738461,0.000103359513766177,"CYP19A1/SRD5A1/ACE",3
"GO:0045792","BP","GO:0045792","negative regulation of cell size","3/173","11/21081",8.53866619290365e-05,0.000265404481738461,0.000103359513766177,"MTOR/AKT1/RHOA",3
"GO:0051918","BP","GO:0051918","negative regulation of fibrinolysis","3/173","11/21081",8.53866619290365e-05,0.000265404481738461,0.000103359513766177,"PLG/SERPINE1/F2",3
"GO:0051967","BP","GO:0051967","negative regulation of synaptic transmission, glutamatergic","3/173","11/21081",8.53866619290365e-05,0.000265404481738461,0.000103359513766177,"DRD2/DRD3/HTR2A",3
"GO:0060159","BP","GO:0060159","regulation of dopamine receptor signaling pathway","3/173","11/21081",8.53866619290365e-05,0.000265404481738461,0.000103359513766177,"DRD2/DRD3/LRRK2",3
"GO:0098917","BP","GO:0098917","retrograde trans-synaptic signaling","3/173","11/21081",8.53866619290365e-05,0.000265404481738461,0.000103359513766177,"FABP5/CNR1/NOS1",3
"GO:0006913","BP","GO:0006913","nucleocytoplasmic transport","12/173","386/21081",8.64181308654251e-05,0.000268414209098824,0.000104531626439249,"PTPN11/MDM2/PTGS2/GSK3B/MAPK1/AKT1/LRRK2/STAT3/MAPK14/CDK1/MMP12/PSEN1",12
"GO:0060419","BP","GO:0060419","heart growth","7/173","127/21081",8.67777480322839e-05,0.000269334296120653,0.00010488994648937,"G6PD/PPARA/MTOR/MAPK1/PIM1/MAPK14/CDK1",7
"GO:0090092","BP","GO:0090092","regulation of transmembrane receptor protein serine/threonine kinase signaling pathway","10/173","272/21081",8.70773219855042e-05,0.000270066818333144,0.00010517522102283,"XIAP/PARP1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SIRT1/ABL1/EP300",10
"GO:0055023","BP","GO:0055023","positive regulation of cardiac muscle tissue growth","5/173","55/21081",8.76817014808156e-05,0.000271742924574752,0.000105827966315668,"MTOR/MAPK1/PIM1/MAPK14/CDK1",5
"GO:0002698","BP","GO:0002698","negative regulation of immune effector process","9/173","220/21081",8.80064799684611e-05,0.000272550680310489,0.000106142539903653,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL2",9
"GO:0030194","BP","GO:0030194","positive regulation of blood coagulation","4/173","29/21081",8.86311466458786e-05,0.0002738863578897,0.000106662708154887,"PLG/SERPINE1/TLR4/F2",4
"GO:0045745","BP","GO:0045745","positive regulation of G protein-coupled receptor signaling pathway","4/173","29/21081",8.86311466458786e-05,0.0002738863578897,0.000106662708154887,"DRD2/PRKCA/NOS1/F2",4
"GO:1900048","BP","GO:1900048","positive regulation of hemostasis","4/173","29/21081",8.86311466458786e-05,0.0002738863578897,0.000106662708154887,"PLG/SERPINE1/TLR4/F2",4
"GO:0090287","BP","GO:0090287","regulation of cellular response to growth factor stimulus","11/173","329/21081",9.027982777082e-05,0.000278778334446377,0.000108567846737859,"XIAP/PRKCB/XDH/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SIRT1/ABL1/EP300",11
"GO:0034637","BP","GO:0034637","cellular carbohydrate biosynthetic process","6/173","89/21081",9.26504469897074e-05,0.000285683417459555,0.000111256972475609,"GSK3B/MTOR/AKT1/AKR1B1/INSR/PPP1CA",6
"GO:0072332","BP","GO:0072332","intrinsic apoptotic signaling pathway by p53 class mediator","6/173","89/21081",9.26504469897074e-05,0.000285683417459555,0.000111256972475609,"MDM2/CHEK2/MIF/MIF/SIRT1/EP300",6
"GO:0051169","BP","GO:0051169","nuclear transport","12/173","389/21081",9.29696746398113e-05,0.000286459860438403,0.000111559351577255,"PTPN11/MDM2/PTGS2/GSK3B/MAPK1/AKT1/LRRK2/STAT3/MAPK14/CDK1/MMP12/PSEN1",12
"GO:0007632","BP","GO:0007632","visual behavior","5/173","56/21081",9.56434530888929e-05,0.000294058633990381,0.00011451862918405,"HMGCR/DRD2/DRD3/MTOR/APP",5
"GO:0042304","BP","GO:0042304","regulation of fatty acid biosynthetic process","5/173","56/21081",9.56434530888929e-05,0.000294058633990381,0.00011451862918405,"FABP5/NR1H3/PTGS2/NR1H2/SIRT1",5
"GO:1990089","BP","GO:1990089","response to nerve growth factor","5/173","56/21081",9.56434530888929e-05,0.000294058633990381,0.00011451862918405,"AKT1/APP/MAPT/MAPT/MAPT",5
"GO:0044773","BP","GO:0044773","mitotic DNA damage checkpoint","7/173","130/21081",0.000100502085846865,0.000308773219640874,0.000120249099175151,"MDM2/CDK2/PRMT1/CHEK2/CCND1/CDK1/EP300",7
"GO:0072522","BP","GO:0072522","purine-containing compound biosynthetic process","9/173","224/21081",0.000100956466035074,0.000309945104178489,0.000120705479622099,"NOS2/NOS3/PARP1/NOS1/STAT3/FASN/ACACA/ACACA/VCP",9
"GO:0035051","BP","GO:0035051","cardiocyte differentiation","8/173","175/21081",0.000101484214557879,0.000311340380979371,0.000121248858282338,"G6PD/PPARA/MAPK3/MTOR/MAPK1/EGFR/NOX4/CDK1",8
"GO:0045737","BP","GO:0045737","positive regulation of cyclin-dependent protein serine/threonine kinase activity","4/173","30/21081",0.000101614558269692,0.000311515337725774,0.000121316993696329,"SRC/AKT1/EGFR/CCND1",4
"GO:0007595","BP","GO:0007595","lactation","5/173","57/21081",0.000104149135137938,0.000318595878474514,0.000124074449954029,"SLC6A3/SLC6A3/XDH/CCND1/STAT5B",5
"GO:0050433","BP","GO:0050433","regulation of catecholamine secretion","5/173","57/21081",0.000104149135137938,0.000318595878474514,0.000124074449954029,"DRD2/CNR1/DRD3/HTR2A/SNCA",5
"GO:0051339","BP","GO:0051339","regulation of lyase activity","5/173","57/21081",0.000104149135137938,0.000318595878474514,0.000124074449954029,"NOS2/DRD2/DRD3/NOS3/NOS1",5
"GO:0071158","BP","GO:0071158","positive regulation of cell cycle arrest","6/173","91/21081",0.000104849916327491,0.00032050884494641,0.000124819438445147,"MDM2/CDK2/PRMT1/CHEK2/CDK1/EP300",6
"GO:0002224","BP","GO:0002224","toll-like receptor signaling pathway","8/173","176/21081",0.00010558366417415,0.000322519762096306,0.000125602572993124,"NR1H4/ESR1/NR1H3/IKBKB/CHUK/TLR4/CTSB/CTSB",8
"GO:0050792","BP","GO:0050792","regulation of viral process","10/173","279/21081",0.000107348424363717,0.00032767489592057,0.00012761019593146,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CXCL8/EP300",10
"GO:0043487","BP","GO:0043487","regulation of RNA stability","9/173","227/21081",0.000111686164692129,0.000340670864161417,0.000132671365017589,"PRKCA/MTOR/AKT1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/MAPK14",9
"GO:0014062","BP","GO:0014062","regulation of serotonin secretion","3/173","12/21081",0.000113162253654913,0.000344125409856131,0.000134016708400451,"CNR1/HTR1A/MAOB",3
"GO:0031392","BP","GO:0031392","regulation of prostaglandin biosynthetic process","3/173","12/21081",0.000113162253654913,0.000344125409856131,0.000134016708400451,"FABP5/PTGS2/SIRT1",3
"GO:0033629","BP","GO:0033629","negative regulation of cell adhesion mediated by integrin","3/173","12/21081",0.000113162253654913,0.000344125409856131,0.000134016708400451,"PTPN11/SERPINE1/CYP1B1",3
"GO:0061517","BP","GO:0061517","macrophage proliferation","3/173","12/21081",0.000113162253654913,0.000344125409856131,0.000134016708400451,"MAPK3/MAPK1/PTK2",3
"GO:0002686","BP","GO:0002686","negative regulation of leukocyte migration","5/173","58/21081",0.000113223658032213,0.000344125409856131,0.000134016708400451,"CYP19A1/AKT1/MIF/MIF/DPP4",5
"GO:0002082","BP","GO:0002082","regulation of oxidative phosphorylation","4/173","31/21081",0.000115924757390794,0.00035138627474815,0.000136844390359117,"SNCA/RHOA/CDK1/VCP",4
"GO:0090140","BP","GO:0090140","regulation of mitochondrial fission","4/173","31/21081",0.000115924757390794,0.00035138627474815,0.000136844390359117,"LRRK2/MAPT/MAPT/MAPT",4
"GO:1902751","BP","GO:1902751","positive regulation of cell cycle G2/M phase transition","4/173","31/21081",0.000115924757390794,0.00035138627474815,0.000136844390359117,"CDK4/CCND1/CDK1/APP",4
"GO:1903828","BP","GO:1903828","negative regulation of cellular protein localization","7/173","133/21081",0.000115943411907956,0.00035138627474815,0.000136844390359117,"BCL2L1/GSK3B/CSK/LRRK2/MAPT/MAPT/MAPT",7
"GO:0030512","BP","GO:0030512","negative regulation of transforming growth factor beta receptor signaling pathway","6/173","93/21081",0.000118292567979283,0.000357995100672346,0.000139418141298121,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SIRT1",6
"GO:0060761","BP","GO:0060761","negative regulation of response to cytokine stimulus","6/173","93/21081",0.000118292567979283,0.000357995100672346,0.000139418141298121,"NR1H4/NR1H3/PPARG/IL6/NR1H2/MMP12",6
"GO:0050870","BP","GO:0050870","positive regulation of T cell activation","10/173","283/21081",0.000120630666613307,0.000364811176113837,0.000142072603795556,"PTPN11/IL6/SRC/CSK/PIK3CA/AKT1/RHOA/STAT5B/DPP4/IL2",10
"GO:0003014","BP","GO:0003014","renal system process","7/173","134/21081",0.000121499124285908,0.000366915265878338,0.00014289202362432,"SLC22A6/DRD2/AGTR1/DRD3/CHRNA3/AKR1B1/RHOA",7
"GO:0017015","BP","GO:0017015","regulation of transforming growth factor beta receptor signaling pathway","7/173","134/21081",0.000121499124285908,0.000366915265878338,0.00014289202362432,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SIRT1/EP300",7
"GO:0010332","BP","GO:0010332","response to gamma radiation","5/173","59/21081",0.000122892479435654,0.000369808884647375,0.000144018918795921,"BCL2L1/MDM2/CHEK2/PARP1/NOX4",5
"GO:0031648","BP","GO:0031648","protein destabilization","5/173","59/21081",0.000122892479435654,0.000369808884647375,0.000144018918795921,"MDM2/SRC/SNCA/SIRT1/EP300",5
"GO:0042306","BP","GO:0042306","regulation of protein import into nucleus","5/173","59/21081",0.000122892479435654,0.000369808884647375,0.000144018918795921,"PTGS2/MAPK1/MAPK14/CDK1/PSEN1",5
"GO:0050432","BP","GO:0050432","catecholamine secretion","5/173","59/21081",0.000122892479435654,0.000369808884647375,0.000144018918795921,"DRD2/CNR1/DRD3/HTR2A/SNCA",5
"GO:0060421","BP","GO:0060421","positive regulation of heart growth","5/173","59/21081",0.000122892479435654,0.000369808884647375,0.000144018918795921,"MTOR/MAPK1/PIM1/MAPK14/CDK1",5
"GO:0045088","BP","GO:0045088","regulation of innate immune response","13/173","466/21081",0.000129859866346704,0.000390498635603076,0.000152076365997705,"PTPN11/NR1H3/DRD2/XIAP/PPARG/NR1H2/SRC/IKBKB/CHUK/TLR4/STAT5B/MMP12/EP300",13
"GO:0051385","BP","GO:0051385","response to mineralocorticoid","4/173","32/21081",0.000131640993059745,0.000395295109194951,0.000153944311764864,"SRC/PARP1/CCND1/MAOB",4
"GO:0071480","BP","GO:0071480","cellular response to gamma radiation","4/173","32/21081",0.000131640993059745,0.000395295109194951,0.000153944311764864,"BCL2L1/MDM2/CHEK2/NOX4",4
"GO:1903845","BP","GO:1903845","negative regulation of cellular response to transforming growth factor beta stimulus","6/173","95/21081",0.000133068102914156,0.000399298283391419,0.000155503313842591,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SIRT1",6
"GO:0042093","BP","GO:0042093","T-helper cell differentiation","5/173","60/21081",0.000133181598619275,0.000399309312589671,0.000155507609069865,"RORA/IL6/MTOR/STAT3/IL2",5
"GO:1903844","BP","GO:1903844","regulation of cellular response to transforming growth factor beta stimulus","7/173","136/21081",0.000133259732937669,0.000399309312589671,0.000155507609069865,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SIRT1/EP300",7
"GO:0002455","BP","GO:0002455","humoral immune response mediated by circulating immunoglobulin","8/173","183/21081",0.00013829059312979,0.000413965849894332,0.00016121547262734,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0000280","BP","GO:0000280","nuclear division","13/173","469/21081",0.000138345847693564,0.000413965849894332,0.00016121547262734,"XIAP/PRKCB/DRD3/PRKCA/CHEK2/INSR/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/RHOA/CDK1",13
"GO:1903793","BP","GO:1903793","positive regulation of anion transport","5/173","61/21081",0.00014411755054164,0.000430932774279683,0.000167823096745404,"MIF/MIF/CFTR/CETP/PSEN1",5
"GO:0001952","BP","GO:0001952","regulation of cell-matrix adhesion","7/173","138/21081",0.000145927726513223,0.000433570057340148,0.000168850164159669,"SERPINE1/SRC/GSK3B/PTK2/RHOA/ABL1/MMP12",7
"GO:0044774","BP","GO:0044774","mitotic DNA integrity checkpoint","7/173","138/21081",0.000145927726513223,0.000433570057340148,0.000168850164159669,"MDM2/CDK2/PRMT1/CHEK2/CCND1/CDK1/EP300",7
"GO:0007077","BP","GO:0007077","mitotic nuclear envelope disassembly","3/173","13/21081",0.000146224027340182,0.000433570057340148,0.000168850164159669,"PRKCB/PRKCA/CDK1",3
"GO:0010739","BP","GO:0010739","positive regulation of protein kinase A signaling","3/173","13/21081",0.000146224027340182,0.000433570057340148,0.000168850164159669,"MIF/MIF/MC1R",3
"GO:0031282","BP","GO:0031282","regulation of guanylate cyclase activity","3/173","13/21081",0.000146224027340182,0.000433570057340148,0.000168850164159669,"NOS2/NOS3/NOS1",3
"GO:0042416","BP","GO:0042416","dopamine biosynthetic process","3/173","13/21081",0.000146224027340182,0.000433570057340148,0.000168850164159669,"SLC6A3/SLC6A3/SNCA",3
"GO:0048148","BP","GO:0048148","behavioral response to cocaine","3/173","13/21081",0.000146224027340182,0.000433570057340148,0.000168850164159669,"DRD2/DRD3/HTR2A",3
"GO:0070673","BP","GO:0070673","response to interleukin-18","3/173","13/21081",0.000146224027340182,0.000433570057340148,0.000168850164159669,"ALOX5/ALOX5/AKT1",3
"GO:0071287","BP","GO:0071287","cellular response to manganese ion","3/173","13/21081",0.000146224027340182,0.000433570057340148,0.000168850164159669,"BACE1/LRRK2/APP",3
"GO:0072584","BP","GO:0072584","caveolin-mediated endocytosis","3/173","13/21081",0.000146224027340182,0.000433570057340148,0.000168850164159669,"MAPK3/SRC/MAPK1",3
"GO:1901503","BP","GO:1901503","ether biosynthetic process","3/173","13/21081",0.000146224027340182,0.000433570057340148,0.000168850164159669,"ALOX5/ALOX5/FASN",3
"GO:1990416","BP","GO:1990416","cellular response to brain-derived neurotrophic factor stimulus","3/173","13/21081",0.000146224027340182,0.000433570057340148,0.000168850164159669,"MAPT/MAPT/MAPT",3
"GO:0034694","BP","GO:0034694","response to prostaglandin","4/173","33/21081",0.00014884380886157,0.000440109494678366,0.00017139689230516,"PPARG/AKT1/ACACA/ACACA",4
"GO:0070229","BP","GO:0070229","negative regulation of lymphocyte apoptotic process","4/173","33/21081",0.00014884380886157,0.000440109494678366,0.00017139689230516,"IDO1/MIF/MIF/IL2",4
"GO:1902230","BP","GO:1902230","negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage","4/173","33/21081",0.00014884380886157,0.000440109494678366,0.00017139689230516,"BCL2L1/MIF/MIF/SIRT1",4
"GO:1903959","BP","GO:1903959","regulation of anion transmembrane transport","4/173","33/21081",0.00014884380886157,0.000440109494678366,0.00017139689230516,"MTOR/AKT1/CFTR/PSEN1",4
"GO:0061013","BP","GO:0061013","regulation of mRNA catabolic process","9/173","237/21081",0.00015460338980352,0.000456821838160749,0.000177905372059976,"PRKCA/MTOR/AKT1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/MAPK14",9
"GO:0002294","BP","GO:0002294","CD4-positive, alpha-beta T cell differentiation involved in immune response","5/173","62/21081",0.000155727399673291,0.000459503973063758,0.000178949906642115,"RORA/IL6/MTOR/STAT3/IL2",5
"GO:0010574","BP","GO:0010574","regulation of vascular endothelial growth factor production","5/173","62/21081",0.000155727399673291,0.000459503973063758,0.000178949906642115,"RORA/PTGS2/IL6/CYP1B1/C5AR1",5
"GO:1901184","BP","GO:1901184","regulation of ERBB signaling pathway","6/173","98/21081",0.000157935788546751,0.000465696853251316,0.00018136167105847,"ERBB2/AKT1/EGFR/MMP9/APP/PSEN1",6
"GO:0043903","BP","GO:0043903","regulation of symbiotic process","10/173","293/21081",0.000160049682028474,0.000471602703841184,0.000183661654243931,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CXCL8/EP300",10
"GO:0017157","BP","GO:0017157","regulation of exocytosis","9/173","239/21081",0.000164656946586474,0.000484842249512078,0.000188817682484544,"BACE1/DRD2/CNR1/PRKCB/GSK3B/HTR2A/LRRK2/SNCA/CFTR",9
"GO:1903531","BP","GO:1903531","negative regulation of secretion by cell","8/173","188/21081",0.000166436122081722,0.000489741747039639,0.000190725750045537,"HMGCR/PTPN11/NR1H3/DRD2/CNR1/DRD3/SNCA/MAOB",8
"GO:0090101","BP","GO:0090101","negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway","7/173","141/21081",0.000166744775116707,0.000490310414858746,0.00019094721288178,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SIRT1/ABL1",7
"GO:0030431","BP","GO:0030431","sleep","4/173","34/21081",0.000167614967652854,0.000490831149246711,0.00019115000845173,"SRD5A1/DRD2/DRD3/HTR2A",4
"GO:0032148","BP","GO:0032148","activation of protein kinase B activity","4/173","34/21081",0.000167614967652854,0.000490831149246711,0.00019115000845173,"SRC/MTOR/AKT1/INSR",4
"GO:0051873","BP","GO:0051873","killing by host of symbiont cells","4/173","34/21081",0.000167614967652854,0.000490831149246711,0.00019115000845173,"F2/CTSG/ELANE/ELANE",4
"GO:0072538","BP","GO:0072538","T-helper 17 type immune response","4/173","34/21081",0.000167614967652854,0.000490831149246711,0.00019115000845173,"RORA/IL6/STAT3/IL2",4
"GO:1902253","BP","GO:1902253","regulation of intrinsic apoptotic signaling pathway by p53 class mediator","4/173","34/21081",0.000167614967652854,0.000490831149246711,0.00019115000845173,"MDM2/MIF/MIF/SIRT1",4
"GO:1904031","BP","GO:1904031","positive regulation of cyclin-dependent protein kinase activity","4/173","34/21081",0.000167614967652854,0.000490831149246711,0.00019115000845173,"SRC/AKT1/EGFR/CCND1",4
"GO:0002287","BP","GO:0002287","alpha-beta T cell activation involved in immune response","5/173","63/21081",0.000168038733575729,0.000491056794335126,0.000191237884008576,"RORA/IL6/MTOR/STAT3/IL2",5
"GO:0002293","BP","GO:0002293","alpha-beta T cell differentiation involved in immune response","5/173","63/21081",0.000168038733575729,0.000491056794335126,0.000191237884008576,"RORA/IL6/MTOR/STAT3/IL2",5
"GO:1904589","BP","GO:1904589","regulation of protein import","5/173","63/21081",0.000168038733575729,0.000491056794335126,0.000191237884008576,"PTGS2/MAPK1/MAPK14/CDK1/PSEN1",5
"GO:0015980","BP","GO:0015980","energy derivation by oxidation of organic compounds","10/173","296/21081",0.000173804703948071,0.000507557516890278,0.000197663949796613,"NOS2/GSK3B/MTOR/PIK3CA/AKT1/INSR/SNCA/PPP1CA/CDK1/VCP",10
"GO:0046887","BP","GO:0046887","positive regulation of hormone secretion","7/173","142/21081",0.000174194712169266,0.000508347068686271,0.000197971434015389,"CYP19A1/NR1H4/PTPN11/DRD2/EGFR/CD38/CFTR",7
"GO:2001021","BP","GO:2001021","negative regulation of response to DNA damage stimulus","6/173","100/21081",0.000176459993959248,0.000514604333790559,0.000200408272588909,"BCL2L1/MDM2/CHEK2/MIF/MIF/SIRT1",6
"GO:0014706","BP","GO:0014706","striated muscle tissue development","12/173","417/21081",0.00017775670118967,0.00051803033151914,0.000201742498209632,"G6PD/PPARA/HMGCR/MTOR/MAPK1/PIM1/HDAC4/RHOA/MAPK14/NOX4/CDK1/EP300",12
"GO:0035966","BP","GO:0035966","response to topologically incorrect protein","9/173","242/21081",0.000180756229432647,0.000526410705181164,0.000205006163318871,"CCND1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/CXCL8/VCP/EP300",9
"GO:0010518","BP","GO:0010518","positive regulation of phospholipase activity","5/173","64/21081",0.00018107965624536,0.000526991410538722,0.000205232314071886,"ESR1/AGTR1/HTR2A/EGFR/C5AR1",5
"GO:0050871","BP","GO:0050871","positive regulation of B cell activation","7/173","143/21081",0.000181911655720906,0.000529050393674284,0.000206034167508386,"IL6/TLR4/MIF/MIF/STAT5B/CD38/IL2",7
"GO:0002903","BP","GO:0002903","negative regulation of B cell apoptotic process","3/173","14/21081",0.000184981748244662,0.000536144234851002,0.000208796803504422,"MIF/MIF/IL2",3
"GO:0046321","BP","GO:0046321","positive regulation of fatty acid oxidation","3/173","14/21081",0.000184981748244662,0.000536144234851002,0.000208796803504422,"PPARA/FABP1/PPARG",3
"GO:0050872","BP","GO:0050872","white fat cell differentiation","3/173","14/21081",0.000184981748244662,0.000536144234851002,0.000208796803504422,"FABP4/PPARG/SIRT1",3
"GO:0090399","BP","GO:0090399","replicative senescence","3/173","14/21081",0.000184981748244662,0.000536144234851002,0.000208796803504422,"SERPINE1/TERT/CHEK2",3
"GO:2001279","BP","GO:2001279","regulation of unsaturated fatty acid biosynthetic process","3/173","14/21081",0.000184981748244662,0.000536144234851002,0.000208796803504422,"FABP5/PTGS2/SIRT1",3
"GO:0090288","BP","GO:0090288","negative regulation of cellular response to growth factor stimulus","8/173","191/21081",0.000185476324257419,0.000537211248650151,0.000209212342935933,"XDH/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SIRT1/ABL1",8
"GO:0007263","BP","GO:0007263","nitric oxide mediated signal transduction","4/173","35/21081",0.000188037378034397,0.000543148075641166,0.000211524389616854,"NOS2/NOS3/NOS1/EGFR",4
"GO:0040018","BP","GO:0040018","positive regulation of multicellular organism growth","4/173","35/21081",0.000188037378034397,0.000543148075641166,0.000211524389616854,"SLC6A3/SLC6A3/DRD2/STAT5B",4
"GO:0043516","BP","GO:0043516","regulation of DNA damage response, signal transduction by p53 class mediator","4/173","35/21081",0.000188037378034397,0.000543148075641166,0.000211524389616854,"MDM2/MIF/MIF/SIRT1",4
"GO:0070102","BP","GO:0070102","interleukin-6-mediated signaling pathway","4/173","35/21081",0.000188037378034397,0.000543148075641166,0.000211524389616854,"PTPN11/IL6/SRC/STAT3",4
"GO:0022029","BP","GO:0022029","telencephalon cell migration","5/173","65/21081",0.000194878781232516,0.000562145241993865,0.000218922674168375,"DRD2/LRRK2/EGFR/RHOA/PSEN1",5
"GO:1902808","BP","GO:1902808","positive regulation of cell cycle G1/S phase transition","5/173","65/21081",0.000194878781232516,0.000562145241993865,0.000218922674168375,"TERT/MDM2/AKT1/EGFR/CCND1",5
"GO:0042100","BP","GO:0042100","B cell proliferation","6/173","102/21081",0.000196659860673312,0.000565363834912654,0.000220176127753327,"TLR4/MIF/MIF/ABL1/CD38/IL2",6
"GO:0045844","BP","GO:0045844","positive regulation of striated muscle tissue development","6/173","102/21081",0.000196659860673312,0.000565363834912654,0.000220176127753327,"HMGCR/MTOR/MAPK1/PIM1/MAPK14/CDK1",6
"GO:0048010","BP","GO:0048010","vascular endothelial growth factor receptor signaling pathway","6/173","102/21081",0.000196659860673312,0.000565363834912654,0.000220176127753327,"PRKCB/SRC/PIK3CA/PTK2/RHOA/MAPK14",6
"GO:0048636","BP","GO:0048636","positive regulation of muscle organ development","6/173","102/21081",0.000196659860673312,0.000565363834912654,0.000220176127753327,"HMGCR/MTOR/MAPK1/PIM1/MAPK14/CDK1",6
"GO:0106027","BP","GO:0106027","neuron projection organization","6/173","102/21081",0.000196659860673312,0.000565363834912654,0.000220176127753327,"IGF1R/GSK3B/LRRK2/INSR/APP/PSEN1",6
"GO:0002431","BP","GO:0002431","Fc receptor mediated stimulatory signaling pathway","7/173","146/21081",0.00020673611773196,0.000593929522814806,0.000231300791484034,"MAPK3/SRC/CSK/PIK3CA/MAPK1/PTK2/ABL1",7
"GO:0033238","BP","GO:0033238","regulation of cellular amine metabolic process","6/173","103/21081",0.000207421199455916,0.000594691414634405,0.000231597503760708,"NR1H4/SLC6A3/SLC6A3/HTR1A/NQO1/MAOB",6
"GO:0046470","BP","GO:0046470","phosphatidylcholine metabolic process","6/173","103/21081",0.000207421199455916,0.000594691414634405,0.000231597503760708,"FABP5/NR1H3/NR1H2/CSNK2A1/CSNK2A2/CETP",6
"GO:1901863","BP","GO:1901863","positive regulation of muscle tissue development","6/173","103/21081",0.000207421199455916,0.000594691414634405,0.000231597503760708,"HMGCR/MTOR/MAPK1/PIM1/MAPK14/CDK1",6
"GO:0030888","BP","GO:0030888","regulation of B cell proliferation","5/173","66/21081",0.000209465224545493,0.000600146823394336,0.000233722066213944,"TLR4/MIF/MIF/CD38/IL2",5
"GO:0016242","BP","GO:0016242","negative regulation of macroautophagy","4/173","36/21081",0.000210195022529999,0.000600617787982493,0.000233905479359472,"MTOR/PIK3CA/AKT1/LRRK2",4
"GO:0051883","BP","GO:0051883","killing of cells in other organism involved in symbiotic interaction","4/173","36/21081",0.000210195022529999,0.000600617787982493,0.000233905479359472,"F2/CTSG/ELANE/ELANE",4
"GO:1901661","BP","GO:1901661","quinone metabolic process","4/173","36/21081",0.000210195022529999,0.000600617787982493,0.000233905479359472,"AKR1B10/HMGCR/AKR1B1/AKR1C1",4
"GO:1901797","BP","GO:1901797","negative regulation of signal transduction by p53 class mediator","4/173","36/21081",0.000210195022529999,0.000600617787982493,0.000233905479359472,"MDM2/MIF/MIF/SIRT1",4
"GO:0030900","BP","GO:0030900","forebrain development","12/173","427/21081",0.000220972439734263,0.000630989177708926,0.000245733358278339,"SRD5A1/SLC6A3/SLC6A3/DRD2/SRC/GSK3B/CSNK2A2/LRRK2/EGFR/RHOA/APP/PSEN1",12
"GO:1904062","BP","GO:1904062","regulation of cation transmembrane transport","11/173","365/21081",0.000223356117744446,0.000637294998732578,0.000248189106540886,"G6PD/DRD2/DRD3/PIK3CG/NOS1/SNCA/F2/MMP9/ABL1/APP/PSEN2",11
"GO:0071695","BP","GO:0071695","anatomical structure maturation","9/173","249/21081",0.000223480712664519,0.000637294998732578,0.000248189106540886,"G6PD/PPARG/MTOR/LRRK2/AKR1B1/RHOA/MMP2/APP/CFTR",9
"GO:0001820","BP","GO:0001820","serotonin secretion","3/173","15/21081",0.00022983420830215,0.000652784459275292,0.000254221344955657,"CNR1/HTR1A/MAOB",3
"GO:0045820","BP","GO:0045820","negative regulation of glycolytic process","3/173","15/21081",0.00022983420830215,0.000652784459275292,0.000254221344955657,"PPARA/HDAC4/STAT3",3
"GO:0048308","BP","GO:0048308","organelle inheritance","3/173","15/21081",0.00022983420830215,0.000652784459275292,0.000254221344955657,"MAPK3/MAPK1/CDK1",3
"GO:0048313","BP","GO:0048313","Golgi inheritance","3/173","15/21081",0.00022983420830215,0.000652784459275292,0.000254221344955657,"MAPK3/MAPK1/CDK1",3
"GO:0051917","BP","GO:0051917","regulation of fibrinolysis","3/173","15/21081",0.00022983420830215,0.000652784459275292,0.000254221344955657,"PLG/SERPINE1/F2",3
"GO:1902474","BP","GO:1902474","positive regulation of protein localization to synapse","3/173","15/21081",0.00022983420830215,0.000652784459275292,0.000254221344955657,"MAPT/MAPT/MAPT",3
"GO:0016054","BP","GO:0016054","organic acid catabolic process","10/173","307/21081",0.000233074866776438,0.00066110487912756,0.000257461661564585,"PPARA/FABP1/NOS2/IDO1/CNR1/MTOR/NOS3/CYP26A1/AKT1/NOS1",10
"GO:0046395","BP","GO:0046395","carboxylic acid catabolic process","10/173","307/21081",0.000233074866776438,0.00066110487912756,0.000257461661564585,"PPARA/FABP1/NOS2/IDO1/CNR1/MTOR/NOS3/CYP26A1/AKT1/NOS1",10
"GO:0010543","BP","GO:0010543","regulation of platelet activation","4/173","37/21081",0.000234172887442339,0.000662891804625248,0.000258157564472356,"PRKCA/NOS3/TLR4/F2",4
"GO:0033028","BP","GO:0033028","myeloid cell apoptotic process","4/173","37/21081",0.000234172887442339,0.000662891804625248,0.000258157564472356,"IL6/MIF/MIF/SIRT1",4
"GO:0042908","BP","GO:0042908","xenobiotic transport","4/173","37/21081",0.000234172887442339,0.000662891804625248,0.000258157564472356,"NR1I2/ABCC1/ABCC1/ABCG2",4
"GO:0007588","BP","GO:0007588","excretion","5/173","68/21081",0.000241118998468324,0.000681646456747776,0.000265461403923525,"DRD2/AGTR1/DRD3/CHRNA3/ABCG2",5
"GO:0021885","BP","GO:0021885","forebrain cell migration","5/173","68/21081",0.000241118998468324,0.000681646456747776,0.000265461403923525,"DRD2/LRRK2/EGFR/RHOA/PSEN1",5
"GO:0000079","BP","GO:0000079","regulation of cyclin-dependent protein serine/threonine kinase activity","6/173","106/21081",0.000242514845816552,0.000684681448421615,0.00026664335556819,"SRC/CDK4/CCNA2/AKT1/EGFR/CCND1",6
"GO:0046364","BP","GO:0046364","monosaccharide biosynthetic process","6/173","106/21081",0.000242514845816552,0.000684681448421615,0.00026664335556819,"G6PD/PPARA/AKR1B1/SIRT1/OGT/EP300",6
"GO:0050770","BP","GO:0050770","regulation of axonogenesis","8/173","199/21081",0.000245168251783522,0.000691713082223231,0.000269381765432094,"GSK3B/PTK2/RHOA/ABL1/MAPT/MAPT/MAPT/PSEN1",8
"GO:0009620","BP","GO:0009620","response to fungus","5/173","69/21081",0.000258247006702979,0.000728129748826117,0.00028356392591561,"TLR4/MPO/CTSG/ELANE/ELANE",5
"GO:0009112","BP","GO:0009112","nucleobase metabolic process","4/173","38/21081",0.000260056894357358,0.000730325012640063,0.00028441885270099,"TTR/MTOR/MAPK1/XDH",4
"GO:0016486","BP","GO:0016486","peptide hormone processing","4/173","38/21081",0.000260056894357358,0.000730325012640063,0.00028441885270099,"CES1/CES1/ACE/CTSG",4
"GO:0045777","BP","GO:0045777","positive regulation of blood pressure","4/173","38/21081",0.000260056894357358,0.000730325012640063,0.00028441885270099,"CNR1/ACE/RHOA/GLP1R",4
"GO:0060045","BP","GO:0060045","positive regulation of cardiac muscle cell proliferation","4/173","38/21081",0.000260056894357358,0.000730325012640063,0.00028441885270099,"MAPK1/PIM1/MAPK14/CDK1",4
"GO:0097421","BP","GO:0097421","liver regeneration","4/173","38/21081",0.000260056894357358,0.000730325012640063,0.00028441885270099,"IL6/CSNK2A2/EGFR/CCND1",4
"GO:0140448","BP","GO:0140448","signaling receptor ligand precursor processing","4/173","38/21081",0.000260056894357358,0.000730325012640063,0.00028441885270099,"CES1/CES1/ACE/CTSG",4
"GO:0007517","BP","GO:0007517","muscle organ development","12/173","435/21081",0.000261717698410411,0.000734503633121424,0.000286046180839301,"G6PD/PPARA/HMGCR/MTOR/MAPK1/PIM1/HDAC4/RHOA/SIRT1/MAPK14/CDK1/EP300",12
"GO:0046651","BP","GO:0046651","lymphocyte proliferation","11/173","372/21081",0.000262805817464754,0.000737070573206428,0.000287045853781201,"IDO1/IL6/ERBB2/PIK3CG/TLR4/MIF/MIF/STAT5B/ABL1/CD38/IL2",11
"GO:0060079","BP","GO:0060079","excitatory postsynaptic potential","6/173","108/21081",0.000268393162231411,0.000752244423694765,0.000292955180549769,"DRD2/GSK3B/AKT1/CHRNA3/LRRK2/APP",6
"GO:0060537","BP","GO:0060537","muscle tissue development","12/173","438/21081",0.00027856397358186,0.00078023620550384,0.000303856341443073,"G6PD/PPARA/HMGCR/MTOR/MAPK1/PIM1/HDAC4/RHOA/MAPK14/NOX4/CDK1/EP300",12
"GO:0002295","BP","GO:0002295","T-helper cell lineage commitment","3/173","16/21081",0.000281169407859654,0.000781864407065229,0.00030449043066642,"IL6/MTOR/STAT3",3
"GO:0010917","BP","GO:0010917","negative regulation of mitochondrial membrane potential","3/173","16/21081",0.000281169407859654,0.000781864407065229,0.00030449043066642,"MAPT/MAPT/MAPT",3
"GO:0017014","BP","GO:0017014","protein nitrosylation","3/173","16/21081",0.000281169407859654,0.000781864407065229,0.00030449043066642,"NOS2/NOS1/ACE",3
"GO:0018119","BP","GO:0018119","peptidyl-cysteine S-nitrosylation","3/173","16/21081",0.000281169407859654,0.000781864407065229,0.00030449043066642,"NOS2/NOS1/ACE",3
"GO:0019896","BP","GO:0019896","axonal transport of mitochondrion","3/173","16/21081",0.000281169407859654,0.000781864407065229,0.00030449043066642,"MAPT/MAPT/MAPT",3
"GO:0021984","BP","GO:0021984","adenohypophysis development","3/173","16/21081",0.000281169407859654,0.000781864407065229,0.00030449043066642,"SLC6A3/SLC6A3/DRD2",3
"GO:0032310","BP","GO:0032310","prostaglandin secretion","3/173","16/21081",0.000281169407859654,0.000781864407065229,0.00030449043066642,"NOS2/MIF/MIF",3
"GO:0045779","BP","GO:0045779","negative regulation of bone resorption","3/173","16/21081",0.000281169407859654,0.000781864407065229,0.00030449043066642,"IL6/CSK/CD38",3
"GO:0071732","BP","GO:0071732","cellular response to nitric oxide","3/173","16/21081",0.000281169407859654,0.000781864407065229,0.00030449043066642,"CDK2/CCNA2/MMP3",3
"GO:1905050","BP","GO:1905050","positive regulation of metallopeptidase activity","3/173","16/21081",0.000281169407859654,0.000781864407065229,0.00030449043066642,"MAPK3/STAT3/MAPK14",3
"GO:1905522","BP","GO:1905522","negative regulation of macrophage migration","3/173","16/21081",0.000281169407859654,0.000781864407065229,0.00030449043066642,"CYP19A1/MIF/MIF",3
"GO:0007612","BP","GO:0007612","learning","7/173","154/21081",0.000286534800089565,0.000796263156036992,0.000310097900754395,"HMGCR/DRD2/PTGS2/DRD3/MTOR/INSR/APP",7
"GO:0006691","BP","GO:0006691","leukotriene metabolic process","4/173","39/21081",0.000287933833268942,0.00079962801147695,0.000311408315031838,"ALOX5/ALOX5/ABCC1/ABCC1",4
"GO:0002292","BP","GO:0002292","T cell differentiation involved in immune response","5/173","71/21081",0.000295260512262281,0.000818904645301849,0.000318915435808923,"RORA/IL6/MTOR/STAT3/IL2",5
"GO:0055025","BP","GO:0055025","positive regulation of cardiac muscle tissue development","5/173","71/21081",0.000295260512262281,0.000818904645301849,0.000318915435808923,"MTOR/MAPK1/PIM1/MAPK14/CDK1",5
"GO:1904029","BP","GO:1904029","regulation of cyclin-dependent protein kinase activity","6/173","110/21081",0.000296393492664467,0.000821510730809734,0.000319930353602185,"SRC/CDK4/CCNA2/AKT1/EGFR/CCND1",6
"GO:0051147","BP","GO:0051147","regulation of muscle cell differentiation","8/173","205/21081",0.000299575808970952,0.000829789838538184,0.000323154581556533,"G6PD/PPARA/MDM2/MTOR/HDAC4/SIRT1/ABL1/MAPK14",8
"GO:0071897","BP","GO:0071897","DNA biosynthetic process","8/173","206/21081",0.000309535089764852,0.000856817326652025,0.000333680206487466,"MAPK3/TERT/PPARG/SRC/MAPK1/SIRT1/NOX4/VCP",8
"GO:0007189","BP","GO:0007189","adenylate cyclase-activating G protein-coupled receptor signaling pathway","7/173","156/21081",0.000309919901444699,0.000857323998202164,0.000333877525405062,"DRD2/CNR1/DRD3/PRKCA/NOS1/MC1R/GLP1R",7
"GO:0051702","BP","GO:0051702","interaction with symbiont","6/173","111/21081",0.000311226949151564,0.000860379510048795,0.000335067468456158,"PLG/F2/CTSG/ELANE/ELANE/EP300",6
"GO:0051898","BP","GO:0051898","negative regulation of protein kinase B signaling","5/173","72/21081",0.00031520949547897,0.000870822591866152,0.000339134437679105,"DRD2/DRD3/AKT1/XDH/SIRT1",5
"GO:0009743","BP","GO:0009743","response to carbohydrate","9/173","261/21081",0.00031615004043263,0.000872853490447203,0.000339925353825173,"NR1H4/HMGCR/IGF1R/PTGS2/PRKCB/PIK3CA/RHOA/NOX4/CFTR",9
"GO:0006699","BP","GO:0006699","bile acid biosynthetic process","4/173","40/21081",0.000317891297296122,0.000877090988448847,0.000341575611312033,"NR1H4/CES1/CES1/SIRT1",4
"GO:0030177","BP","GO:0030177","positive regulation of Wnt signaling pathway","8/173","207/21081",0.00031976320790761,0.000881683238416247,0.000343364023928934,"TERT/XIAP/SRC/CSNK2A1/LRRK2/EGFR/ABL1/VCP",8
"GO:0106106","BP","GO:0106106","cold-induced thermogenesis","7/173","157/21081",0.000322173761835287,0.000887178427762887,0.000345504078592674,"FABP4/FABP5/IGF1R/NR1H3/NR1H2/TLR4/OGT",7
"GO:0120161","BP","GO:0120161","regulation of cold-induced thermogenesis","7/173","157/21081",0.000322173761835287,0.000887178427762887,0.000345504078592674,"FABP4/FABP5/IGF1R/NR1H3/NR1H2/TLR4/OGT",7
"GO:0002285","BP","GO:0002285","lymphocyte activation involved in immune response","8/173","208/21081",0.000330265631595932,0.000908872194722225,0.000353952531271342,"RORA/IL6/MTOR/TLR4/ABL1/STAT3/IL2/PSEN1",8
"GO:0033692","BP","GO:0033692","cellular polysaccharide biosynthetic process","5/173","73/21081",0.000336163041062913,0.000924502758237097,0.000360039721036211,"GSK3B/MTOR/AKT1/INSR/PPP1CA",5
"GO:0002833","BP","GO:0002833","positive regulation of response to biotic stimulus","11/173","383/21081",0.000336633881928065,0.000925198812621183,0.000360310793484659,"MAPK3/SRC/PRKCA/IKBKB/CHUK/TLR4/MIF/MIF/STAT5B/MMP12/EP300",11
"GO:0006527","BP","GO:0006527","arginine catabolic process","3/173","17/21081",0.000339364734963057,0.00092850016668257,0.000361596477691345,"NOS2/NOS3/NOS1",3
"GO:0030397","BP","GO:0030397","membrane disassembly","3/173","17/21081",0.000339364734963057,0.00092850016668257,0.000361596477691345,"PRKCB/PRKCA/CDK1",3
"GO:0034374","BP","GO:0034374","low-density lipoprotein particle remodeling","3/173","17/21081",0.000339364734963057,0.00092850016668257,0.000361596477691345,"AGTR1/MPO/CETP",3
"GO:0042448","BP","GO:0042448","progesterone metabolic process","3/173","17/21081",0.000339364734963057,0.00092850016668257,0.000361596477691345,"SRD5A1/AKR1C1/STAT5B",3
"GO:0045837","BP","GO:0045837","negative regulation of membrane potential","3/173","17/21081",0.000339364734963057,0.00092850016668257,0.000361596477691345,"MAPT/MAPT/MAPT",3
"GO:0051081","BP","GO:0051081","nuclear envelope disassembly","3/173","17/21081",0.000339364734963057,0.00092850016668257,0.000361596477691345,"PRKCB/PRKCA/CDK1",3
"GO:2000811","BP","GO:2000811","negative regulation of anoikis","3/173","17/21081",0.000339364734963057,0.00092850016668257,0.000361596477691345,"SRC/PIK3CA/PTK2",3
"GO:0008016","BP","GO:0008016","regulation of heart contraction","9/173","264/21081",0.000343713061481858,0.000939187651598981,0.000365758627618535,"DRD2/MDM2/PIK3CG/NOS3/NOS1/HDAC4/GLP1R/IL2/CACNA1B",9
"GO:0016064","BP","GO:0016064","immunoglobulin mediated immune response","9/173","264/21081",0.000343713061481858,0.000939187651598981,0.000365758627618535,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL2",9
"GO:0051146","BP","GO:0051146","striated muscle cell differentiation","10/173","323/21081",0.00034892228396806,0.000952808987519463,0.000371063340818421,"G6PD/PPARA/MTOR/CHUK/AKT1/NOS1/HDAC4/MAPK14/NOX4/CDK1",10
"GO:0008207","BP","GO:0008207","C21-steroid hormone metabolic process","4/173","41/21081",0.000350017618965416,0.000953960784466999,0.00037151189832459,"SRD5A1/AKR1B1/AKR1C1/STAT5B",4
"GO:1902042","BP","GO:1902042","negative regulation of extrinsic apoptotic signaling pathway via death domain receptors","4/173","41/21081",0.000350017618965416,0.000953960784466999,0.00037151189832459,"SERPINE1/BCL2L1/GSK3B/NOS3",4
"GO:1902229","BP","GO:1902229","regulation of intrinsic apoptotic signaling pathway in response to DNA damage","4/173","41/21081",0.000350017618965416,0.000953960784466999,0.00037151189832459,"BCL2L1/MIF/MIF/SIRT1",4
"GO:0048588","BP","GO:0048588","developmental cell growth","9/173","265/21081",0.000353330419885055,0.000962372406468974,0.00037478773283354,"G6PD/PPARA/GSK3B/MTOR/ABL1/APP/MAPT/MAPT/MAPT",9
"GO:0010812","BP","GO:0010812","negative regulation of cell-substrate adhesion","5/173","74/21081",0.000358154006525182,0.000974885569330876,0.000379660877479069,"PLG/SERPINE1/SRC/RHOA/MMP12",5
"GO:0031644","BP","GO:0031644","regulation of nervous system process","7/173","160/21081",0.000361285901806032,0.000982780919829596,0.00038273565445049,"FABP5/SRC/MTOR/NOS3/LRRK2/APP/MGLL",7
"GO:0019933","BP","GO:0019933","cAMP-mediated signaling","8/173","212/21081",0.000375130195558817,0.00101978771652554,0.000397147636069947,"DRD2/CNR1/PDE4A/DRD3/PRKCA/NOS1/MC1R/GLP1R",8
"GO:0005977","BP","GO:0005977","glycogen metabolic process","5/173","75/21081",0.000381215679821737,0.00103566842938783,0.000403332244366517,"GSK3B/MTOR/AKT1/INSR/PPP1CA",5
"GO:0007212","BP","GO:0007212","dopamine receptor signaling pathway","4/173","42/21081",0.000384401808031296,0.00104365704940893,0.000406443344358632,"DRD2/DRD3/GSK3B/LRRK2",4
"GO:0051048","BP","GO:0051048","negative regulation of secretion","8/173","213/21081",0.000387088621857902,0.00105028068599887,0.0004090228631852,"HMGCR/PTPN11/NR1H3/DRD2/CNR1/DRD3/SNCA/MAOB",8
"GO:0007586","BP","GO:0007586","digestion","7/173","162/21081",0.000389409593258963,0.00105523046030442,0.000410950510608949,"NPC1L1/FABP1/NR1H3/NR1H2/DRD3/TLR4/AKR1C1",7
"GO:0071322","BP","GO:0071322","cellular response to carbohydrate stimulus","7/173","162/21081",0.000389409593258963,0.00105523046030442,0.000410950510608949,"NR1H4/HMGCR/IGF1R/PRKCB/PIK3CA/NOX4/CFTR",7
"GO:0001938","BP","GO:0001938","positive regulation of endothelial cell proliferation","6/173","116/21081",0.000394349749533355,0.00106793631980065,0.000415898699316651,"AGTR1/PRKCA/MTOR/AKT1/SIRT1/STAT3",6
"GO:0031056","BP","GO:0031056","regulation of histone modification","7/173","163/21081",0.000404113778625188,0.00109368117540027,0.000425924813944885,"MAPK3/MAPK8/NOS1/LRRK2/SNCA/SIRT1/OGT",7
"GO:0019372","BP","GO:0019372","lipoxygenase pathway","3/173","18/21081",0.000404787142218643,0.00109410977562787,0.000426091728651203,"ALOX5/ALOX5/PTGS2",3
"GO:1902166","BP","GO:1902166","negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator","3/173","18/21081",0.000404787142218643,0.00109410977562787,0.000426091728651203,"MIF/MIF/SIRT1",3
"GO:0045807","BP","GO:0045807","positive regulation of endocytosis","6/173","117/21081",0.000412877797436294,0.00111456020413393,0.000434055973764364,"SERPINE1/DRD2/PPARG/LRRK2/INSR/SNCA",6
"GO:0097006","BP","GO:0097006","regulation of plasma lipoprotein particle levels","6/173","117/21081",0.000412877797436294,0.00111456020413393,0.000434055973764364,"NR1H4/AGTR1/NR1H2/CSK/MPO/CETP",6
"GO:0006469","BP","GO:0006469","negative regulation of protein kinase activity","9/173","271/21081",0.000415819049149978,0.0011217873903735,0.000436870539858825,"FABP4/HMGCR/IGF1R/AKT1/SNCA/SIRT1/ABL1/PPP2CA/PSEN1",9
"GO:0034767","BP","GO:0034767","positive regulation of ion transmembrane transport","7/173","164/21081",0.000419258759213431,0.00112963250976403,0.000439925754753205,"G6PD/NOS1/SNCA/F2/ABL1/CFTR/PSEN1",7
"GO:0051224","BP","GO:0051224","negative regulation of protein transport","7/173","164/21081",0.000419258759213431,0.00112963250976403,0.000439925754753205,"HMGCR/PTPN11/NR1H3/DRD2/DRD3/CSK/LRRK2",7
"GO:0008631","BP","GO:0008631","intrinsic apoptotic signaling pathway in response to oxidative stress","4/173","43/21081",0.000421133490808223,0.00113396464033215,0.000441612866086669,"AKT1/PARP1/SIRT1/CYP1B1",4
"GO:0010769","BP","GO:0010769","regulation of cell morphogenesis involved in differentiation","10/173","331/21081",0.000422837889722958,0.00113783292807653,0.000443119337785067,"GSK3B/CHRNA3/LRRK2/PTK2/RHOA/ABL1/MAPT/MAPT/MAPT/PSEN1",10
"GO:0006073","BP","GO:0006073","cellular glucan metabolic process","5/173","77/21081",0.000430686401351244,0.00115602433312788,0.000450203825464079,"GSK3B/MTOR/AKT1/INSR/PPP1CA",5
"GO:0044042","BP","GO:0044042","glucan metabolic process","5/173","77/21081",0.000430686401351244,0.00115602433312788,0.000450203825464079,"GSK3B/MTOR/AKT1/INSR/PPP1CA",5
"GO:0072091","BP","GO:0072091","regulation of stem cell proliferation","5/173","77/21081",0.000430686401351244,0.00115602433312788,0.000450203825464079,"TERT/DRD2/PIM1/LRRK2/ACE",5
"GO:1901983","BP","GO:1901983","regulation of protein acetylation","5/173","77/21081",0.000430686401351244,0.00115602433312788,0.000450203825464079,"MAPK3/GSK3B/NOS1/SNCA/SIRT1",5
"GO:0099565","BP","GO:0099565","chemical synaptic transmission, postsynaptic","6/173","118/21081",0.00043207880615182,0.00115902957534033,0.000451374191434517,"DRD2/GSK3B/AKT1/CHRNA3/LRRK2/APP",6
"GO:0019724","BP","GO:0019724","B cell mediated immunity","9/173","274/21081",0.000450321084025102,0.00120644028122488,0.000469837886830465,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL2",9
"GO:0061448","BP","GO:0061448","connective tissue development","9/173","274/21081",0.000450321084025102,0.00120644028122488,0.000469837886830465,"NR1H4/MAPK3/PTPN11/PIK3CA/CDK4/SIRT1/MAPK14/ESRRA/MMP13",9
"GO:0007034","BP","GO:0007034","vacuolar transport","7/173","166/21081",0.000450909518989837,0.00120649530616361,0.000469859315823959,"LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/VCP",7
"GO:0050773","BP","GO:0050773","regulation of dendrite development","7/173","166/21081",0.000450909518989837,0.00120649530616361,0.000469859315823959,"GSK3B/MTOR/CHRNA3/LRRK2/RHOA/IL2/PSEN1",7
"GO:0006635","BP","GO:0006635","fatty acid beta-oxidation","5/173","78/21081",0.000457164098385265,0.00122092410687555,0.000475478489306055,"PPARA/FABP1/CNR1/MTOR/AKT1",5
"GO:0009205","BP","GO:0009205","purine ribonucleoside triphosphate metabolic process","5/173","78/21081",0.000457164098385265,0.00122092410687555,0.000475478489306055,"PARP1/LRRK2/RHOA/STAT3/VCP",5
"GO:0043367","BP","GO:0043367","CD4-positive, alpha-beta T cell differentiation","5/173","78/21081",0.000457164098385265,0.00122092410687555,0.000475478489306055,"RORA/IL6/MTOR/STAT3/IL2",5
"GO:0010955","BP","GO:0010955","negative regulation of protein processing","4/173","44/21081",0.000460302850987995,0.00122699298233876,0.000477841961139225,"SERPINE1/MDM2/XIAP/LRRK2",4
"GO:0060292","BP","GO:0060292","long-term synaptic depression","4/173","44/21081",0.000460302850987995,0.00122699298233876,0.000477841961139225,"CD38/MAPT/MAPT/MAPT",4
"GO:1903318","BP","GO:1903318","negative regulation of protein maturation","4/173","44/21081",0.000460302850987995,0.00122699298233876,0.000477841961139225,"SERPINE1/MDM2/XIAP/LRRK2",4
"GO:0030098","BP","GO:0030098","lymphocyte differentiation","11/173","398/21081",0.000464857757473344,0.0012383577501594,0.000482267873121991,"RORA/IL6/ERBB2/MTOR/HDAC4/RHOA/STAT5B/ABL1/STAT3/IL2/EP300",11
"GO:0002286","BP","GO:0002286","T cell activation involved in immune response","6/173","120/21081",0.000472567554938762,0.00125810748178872,0.000489959237807502,"RORA/IL6/MTOR/STAT3/IL2/PSEN1",6
"GO:0015732","BP","GO:0015732","prostaglandin transport","3/173","19/21081",0.000477793321259605,0.00126567569952124,0.000492906615710789,"NOS2/MIF/MIF",3
"GO:0030540","BP","GO:0030540","female genitalia development","3/173","19/21081",0.000477793321259605,0.00126567569952124,0.000492906615710789,"CYP19A1/SRD5A1/ESR1",3
"GO:0032026","BP","GO:0032026","response to magnesium ion","3/173","19/21081",0.000477793321259605,0.00126567569952124,0.000492906615710789,"MDM2/CCND1/SNCA",3
"GO:0043373","BP","GO:0043373","CD4-positive, alpha-beta T cell lineage commitment","3/173","19/21081",0.000477793321259605,0.00126567569952124,0.000492906615710789,"IL6/MTOR/STAT3",3
"GO:0060033","BP","GO:0060033","anatomical structure regression","3/173","19/21081",0.000477793321259605,0.00126567569952124,0.000492906615710789,"SLC6A3/SLC6A3/DRD2",3
"GO:0090336","BP","GO:0090336","positive regulation of brown fat cell differentiation","3/173","19/21081",0.000477793321259605,0.00126567569952124,0.000492906615710789,"PTGS2/PIM1/MAPK14",3
"GO:1902170","BP","GO:1902170","cellular response to reactive nitrogen species","3/173","19/21081",0.000477793321259605,0.00126567569952124,0.000492906615710789,"CDK2/CCNA2/MMP3",3
"GO:2000641","BP","GO:2000641","regulation of early endosome to late endosome transport","3/173","19/21081",0.000477793321259605,0.00126567569952124,0.000492906615710789,"MAPK3/SRC/MAPK1",3
"GO:0050821","BP","GO:0050821","protein stabilization","8/173","220/21081",0.0004797768186442,0.00127013813234841,0.000494644472148668,"CHEK2/PIM1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/EP300",8
"GO:1990845","BP","GO:1990845","adaptive thermogenesis","7/173","169/21081",0.000501934785654205,0.00132402261332941,0.000515629324089589,"FABP4/FABP5/IGF1R/NR1H3/NR1H2/TLR4/OGT",7
"GO:0021983","BP","GO:0021983","pituitary gland development","4/173","45/21081",0.000502000571916611,0.00132402261332941,0.000515629324089589,"SRD5A1/SLC6A3/SLC6A3/DRD2",4
"GO:0031670","BP","GO:0031670","cellular response to nutrient","4/173","45/21081",0.000502000571916611,0.00132402261332941,0.000515629324089589,"NR1H4/MDM2/PPARG/PIM1",4
"GO:0032620","BP","GO:0032620","interleukin-17 production","4/173","45/21081",0.000502000571916611,0.00132402261332941,0.000515629324089589,"NR1H4/IL6/TLR4/IL2",4
"GO:0060612","BP","GO:0060612","adipose tissue development","4/173","45/21081",0.000502000571916611,0.00132402261332941,0.000515629324089589,"NR1H4/PIK3CA/CDK4/SIRT1",4
"GO:0061082","BP","GO:0061082","myeloid leukocyte cytokine production","4/173","45/21081",0.000502000571916611,0.00132402261332941,0.000515629324089589,"TLR4/MIF/MIF/SIRT1",4
"GO:0030217","BP","GO:0030217","T cell differentiation","9/173","279/21081",0.000513044177819507,0.00135173124232713,0.000526420213533399,"RORA/IL6/ERBB2/MTOR/RHOA/STAT5B/ABL1/STAT3/IL2",9
"GO:0000271","BP","GO:0000271","polysaccharide biosynthetic process","5/173","80/21081",0.000513778761204592,0.00135173124232713,0.000526420213533399,"GSK3B/MTOR/AKT1/INSR/PPP1CA",5
"GO:0070227","BP","GO:0070227","lymphocyte apoptotic process","5/173","80/21081",0.000513778761204592,0.00135173124232713,0.000526420213533399,"IDO1/AKT1/MIF/MIF/IL2",5
"GO:1901616","BP","GO:1901616","organic hydroxy compound catabolic process","5/173","80/21081",0.000513778761204592,0.00135173124232713,0.000526420213533399,"AKR1B10/SLC6A3/SLC6A3/MAOA/MAOB",5
"GO:0001678","BP","GO:0001678","cellular glucose homeostasis","7/173","170/21081",0.000519929695782629,0.00136706762214133,0.000532392835962932,"NR1H4/HMGCR/IGF1R/PIK3CA/SIRT1/NOX4/CFTR",7
"GO:0006275","BP","GO:0006275","regulation of DNA replication","6/173","123/21081",0.000538777408499652,0.00141574842839519,0.000551351161124534,"CDK2/CHEK2/CCNA2/EGFR/CDK1/PPP2CA",6
"GO:0008306","BP","GO:0008306","associative learning","5/173","81/21081",0.00054398671658474,0.0014267898510917,0.000555651149104101,"HMGCR/DRD2/DRD3/MTOR/APP",5
"GO:0046503","BP","GO:0046503","glycerolipid catabolic process","5/173","81/21081",0.00054398671658474,0.0014267898510917,0.000555651149104101,"FABP4/FABP5/FABP1/PIK3CG/MGLL",5
"GO:0070613","BP","GO:0070613","regulation of protein processing","5/173","81/21081",0.00054398671658474,0.0014267898510917,0.000555651149104101,"SERPINE1/MDM2/XIAP/SRC/LRRK2",5
"GO:0000266","BP","GO:0000266","mitochondrial fission","4/173","46/21081",0.000546317780305158,0.00143201989421136,0.000557687944829188,"LRRK2/MAPT/MAPT/MAPT",4
"GO:0055067","BP","GO:0055067","monovalent inorganic cation homeostasis","7/173","172/21081",0.000557460727431986,0.00145915380345556,0.00056825501456247,"MAPK3/DRD2/AGTR1/DRD3/MAPK1/LRRK2/CFTR",7
"GO:0044320","BP","GO:0044320","cellular response to leptin stimulus","3/173","20/21081",0.000558729874846362,0.00145915380345556,0.00056825501456247,"CCNA2/SIRT1/STAT3",3
"GO:0046851","BP","GO:0046851","negative regulation of bone remodeling","3/173","20/21081",0.000558729874846362,0.00145915380345556,0.00056825501456247,"IL6/CSK/CD38",3
"GO:0071731","BP","GO:0071731","response to nitric oxide","3/173","20/21081",0.000558729874846362,0.00145915380345556,0.00056825501456247,"CDK2/CCNA2/MMP3",3
"GO:1902165","BP","GO:1902165","regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator","3/173","20/21081",0.000558729874846362,0.00145915380345556,0.00056825501456247,"MIF/MIF/SIRT1",3
"GO:2001169","BP","GO:2001169","regulation of ATP biosynthetic process","3/173","20/21081",0.000558729874846362,0.00145915380345556,0.00056825501456247,"PARP1/STAT3/VCP",3
"GO:0061180","BP","GO:0061180","mammary gland epithelium development","5/173","82/21081",0.000575509698801696,0.00150205203329755,0.000584961364616751,"ESR1/SRC/MAPK1/AKT1/CCND1",5
"GO:0051209","BP","GO:0051209","release of sequestered calcium ion into cytosol","6/173","125/21081",0.000586775399030177,0.00153051483761769,0.000596045961213168,"DRD2/HTR2A/NOS1/SNCA/F2/ABL1",6
"GO:0010613","BP","GO:0010613","positive regulation of cardiac muscle hypertrophy","4/173","47/21081",0.000593345991349686,0.0015448082826255,0.000601612421569728,"PRKCA/MTOR/PARP1/PTK2",4
"GO:0010863","BP","GO:0010863","positive regulation of phospholipase C activity","4/173","47/21081",0.000593345991349686,0.0015448082826255,0.000601612421569728,"ESR1/HTR2A/EGFR/C5AR1",4
"GO:0034198","BP","GO:0034198","cellular response to amino acid starvation","4/173","47/21081",0.000593345991349686,0.0015448082826255,0.000601612421569728,"MAPK3/MAPK8/MTOR/MAPK1",4
"GO:0007088","BP","GO:0007088","regulation of mitotic nuclear division","7/173","174/21081",0.000597116563537631,0.00155367316501616,0.000605064774474591,"DRD3/INSR/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",7
"GO:0031640","BP","GO:0031640","killing of cells of other organism","5/173","83/21081",0.000608384115220815,0.00158105449882156,0.000615728201594799,"NOS2/F2/CTSG/ELANE/ELANE",5
"GO:1903317","BP","GO:1903317","regulation of protein maturation","5/173","83/21081",0.000608384115220815,0.00158105449882156,0.000615728201594799,"SERPINE1/MDM2/XIAP/SRC/LRRK2",5
"GO:0051283","BP","GO:0051283","negative regulation of sequestering of calcium ion","6/173","126/21081",0.000611986244199997,0.00158944349120158,0.000618995223190321,"DRD2/HTR2A/NOS1/SNCA/F2/ABL1",6
"GO:0009199","BP","GO:0009199","ribonucleoside triphosphate metabolic process","5/173","84/21081",0.000642646721185008,0.00166434793404065,0.000648166120155059,"PARP1/LRRK2/RHOA/STAT3/VCP",5
"GO:0009746","BP","GO:0009746","response to hexose","8/173","230/21081",0.000642676873886651,0.00166434793404065,0.000648166120155059,"NR1H4/HMGCR/IGF1R/PTGS2/PIK3CA/RHOA/NOX4/CFTR",8
"GO:0007618","BP","GO:0007618","mating","4/173","48/21081",0.000643177055235291,0.00166434793404065,0.000648166120155059,"CNR1/HDAC4/MTNR1A/APP",4
"GO:0014742","BP","GO:0014742","positive regulation of muscle hypertrophy","4/173","48/21081",0.000643177055235291,0.00166434793404065,0.000648166120155059,"PRKCA/MTOR/PARP1/PTK2",4
"GO:0046688","BP","GO:0046688","response to copper ion","4/173","48/21081",0.000643177055235291,0.00166434793404065,0.000648166120155059,"BACE1/SNCA/CDK1/APP",4
"GO:1904036","BP","GO:1904036","negative regulation of epithelial cell apoptotic process","4/173","48/21081",0.000643177055235291,0.00166434793404065,0.000648166120155059,"SERPINE1/TERT/MTOR/ABL1",4
"GO:0030728","BP","GO:0030728","ovulation","3/173","21/21081",0.000647933486629115,0.0016725816431878,0.000651372668018782,"PTGS2/NOS3/SIRT1",3
"GO:0035813","BP","GO:0035813","regulation of renal sodium excretion","3/173","21/21081",0.000647933486629115,0.0016725816431878,0.000651372668018782,"DRD2/AGTR1/DRD3",3
"GO:0071498","BP","GO:0071498","cellular response to fluid shear stress","3/173","21/21081",0.000647933486629115,0.0016725816431878,0.000651372668018782,"SREBF2/PTGS2/SRC",3
"GO:1902644","BP","GO:1902644","tertiary alcohol metabolic process","3/173","21/21081",0.000647933486629115,0.0016725816431878,0.000651372668018782,"AKR1B10/AKR1B1/AKR1C1",3
"GO:1903305","BP","GO:1903305","regulation of regulated secretory pathway","7/173","177/21081",0.000660771725817887,0.00170468674134803,0.000663875724913379,"BACE1/DRD2/CNR1/PRKCB/GSK3B/HTR2A/LRRK2",7
"GO:0051282","BP","GO:0051282","regulation of sequestering of calcium ion","6/173","128/21081",0.000664924321229134,0.00171435888404283,0.000667642458464614,"DRD2/HTR2A/NOS1/SNCA/F2/ABL1",6
"GO:1901991","BP","GO:1901991","negative regulation of mitotic cell cycle phase transition","9/173","290/21081",0.000676512292312678,0.00174317812615923,0.000678865866723392,"MDM2/CDK2/PRMT1/CHEK2/CDK4/WEE1/CCND1/CDK1/EP300",9
"GO:0014855","BP","GO:0014855","striated muscle cell proliferation","5/173","85/21081",0.000678334610436307,0.00174469961243576,0.000679458396588425,"MAPK1/PIM1/STAT3/MAPK14/CDK1",5
"GO:0051926","BP","GO:0051926","negative regulation of calcium ion transport","5/173","85/21081",0.000678334610436307,0.00174469961243576,0.000679458396588425,"DRD2/PTGS2/DRD3/NOS3/NOS1",5
"GO:0061515","BP","GO:0061515","myeloid cell development","5/173","85/21081",0.000678334610436307,0.00174469961243576,0.000679458396588425,"G6PD/PTPN11/SRC/APP/EP300",5
"GO:0032365","BP","GO:0032365","intracellular lipid transport","4/173","49/21081",0.000695903105000097,0.00178664186897004,0.000695792450984356,"CES1/CES1/ACACA/ACACA",4
"GO:0046717","BP","GO:0046717","acid secretion","4/173","49/21081",0.000695903105000097,0.00178664186897004,0.000695792450984356,"CES1/CES1/DRD2/DRD3",4
"GO:0051646","BP","GO:0051646","mitochondrion localization","4/173","49/21081",0.000695903105000097,0.00178664186897004,0.000695792450984356,"LRRK2/MAPT/MAPT/MAPT",4
"GO:0010810","BP","GO:0010810","regulation of cell-substrate adhesion","8/173","233/21081",0.000699413188369456,0.00179456922547211,0.000698879692421043,"PLG/SERPINE1/SRC/GSK3B/PTK2/RHOA/ABL1/MMP12",8
"GO:0009144","BP","GO:0009144","purine nucleoside triphosphate metabolic process","5/173","86/21081",0.00071548520547776,0.00183469923842788,0.000714507983998373,"PARP1/LRRK2/RHOA/STAT3/VCP",5
"GO:0031346","BP","GO:0031346","positive regulation of cell projection organization","11/173","420/21081",0.000725231593438816,0.00185856998825183,0.000723804244102482,"CNR1/SRC/MTOR/HDAC4/RHOA/MAPT/MAPT/MAPT/IL2/EP300/PSEN1",11
"GO:0034284","BP","GO:0034284","response to monosaccharide","8/173","235/21081",0.000739431853766711,0.00189381913601854,0.000737531724324272,"NR1H4/HMGCR/IGF1R/PTGS2/PIK3CA/RHOA/NOX4/CFTR",8
"GO:0009713","BP","GO:0009713","catechol-containing compound biosynthetic process","3/173","22/21081",0.000745731088600865,0.00190192760832237,0.000740689499766576,"SLC6A3/SLC6A3/SNCA",3
"GO:0016137","BP","GO:0016137","glycoside metabolic process","3/173","22/21081",0.000745731088600865,0.00190192760832237,0.000740689499766576,"AKR1B10/AKR1B1/AKR1C1",3
"GO:0042423","BP","GO:0042423","catecholamine biosynthetic process","3/173","22/21081",0.000745731088600865,0.00190192760832237,0.000740689499766576,"SLC6A3/SLC6A3/SNCA",3
"GO:0043369","BP","GO:0043369","CD4-positive or CD8-positive, alpha-beta T cell lineage commitment","3/173","22/21081",0.000745731088600865,0.00190192760832237,0.000740689499766576,"IL6/MTOR/STAT3",3
"GO:0050802","BP","GO:0050802","circadian sleep/wake cycle, sleep","3/173","22/21081",0.000745731088600865,0.00190192760832237,0.000740689499766576,"SRD5A1/DRD2/DRD3",3
"GO:0051900","BP","GO:0051900","regulation of mitochondrial depolarization","3/173","22/21081",0.000745731088600865,0.00190192760832237,0.000740689499766576,"SRC/PARP1/LRRK2",3
"GO:0060716","BP","GO:0060716","labyrinthine layer blood vessel development","3/173","22/21081",0.000745731088600865,0.00190192760832237,0.000740689499766576,"PLG/MAPK1/AKT1",3
"GO:0001523","BP","GO:0001523","retinoid metabolic process","6/173","131/21081",0.000750906273134153,0.00191234642686738,0.000744747019864867,"AKR1B10/TTR/CYP26A1/AKR1B1/AKR1C1/CYP1B1",6
"GO:0051208","BP","GO:0051208","sequestering of calcium ion","6/173","131/21081",0.000750906273134153,0.00191234642686738,0.000744747019864867,"DRD2/HTR2A/NOS1/SNCA/F2/ABL1",6
"GO:1903727","BP","GO:1903727","positive regulation of phospholipid metabolic process","4/173","50/21081",0.000751616505735122,0.00191234642686738,0.000744747019864867,"NR1H4/SRC/HTR2A/PTK2",4
"GO:1990928","BP","GO:1990928","response to amino acid starvation","4/173","50/21081",0.000751616505735122,0.00191234642686738,0.000744747019864867,"MAPK3/MAPK8/MTOR/MAPK1",4
"GO:0006937","BP","GO:0006937","regulation of muscle contraction","7/173","181/21081",0.000753894836423344,0.00191699530817642,0.000746557487075182,"PTGS2/TACR1/PIK3CG/CHRNA3/NOS1/HDAC4/RHOA",7
"GO:0045665","BP","GO:0045665","negative regulation of neuron differentiation","8/173","236/21081",0.000760121668743098,0.00193167282924008,0.00075227352257879,"MDM2/GSK3B/LRRK2/PTK2/RHOA/APP/CD38/PSEN1",8
"GO:0019935","BP","GO:0019935","cyclic-nucleotide-mediated signaling","8/173","237/21081",0.00078127514573662,0.00198424273415116,0.000772746424071455,"DRD2/CNR1/PDE4A/DRD3/PRKCA/NOS1/MC1R/GLP1R",8
"GO:0006112","BP","GO:0006112","energy reserve metabolic process","5/173","88/21081",0.000794325788548703,0.0020137770140474,0.00078424829770039,"GSK3B/MTOR/AKT1/INSR/PPP1CA",5
"GO:0010833","BP","GO:0010833","telomere maintenance via telomere lengthening","5/173","88/21081",0.000794325788548703,0.0020137770140474,0.00078424829770039,"MAPK3/TERT/SRC/MAPK1/PARP1",5
"GO:0021954","BP","GO:0021954","central nervous system neuron development","5/173","88/21081",0.000794325788548703,0.0020137770140474,0.00078424829770039,"DRD2/PTK2/MAPT/MAPT/MAPT",5
"GO:0007411","BP","GO:0007411","axon guidance","9/173","297/21081",0.000801099474830862,0.00202973862167939,0.000790464409775674,"MAPK3/PTPN11/SRC/ERBB2/PRKCA/PIK3CA/MAPK1/PTK2/APP",9
"GO:0006111","BP","GO:0006111","regulation of gluconeogenesis","4/173","51/21081",0.000810409805096354,0.00204722429361142,0.000797274055705281,"PPARA/SIRT1/OGT/EP300",4
"GO:0030195","BP","GO:0030195","negative regulation of blood coagulation","4/173","51/21081",0.000810409805096354,0.00204722429361142,0.000797274055705281,"PLG/SERPINE1/NOS3/F2",4
"GO:0045058","BP","GO:0045058","T cell selection","4/173","51/21081",0.000810409805096354,0.00204722429361142,0.000797274055705281,"IL6/MTOR/RHOA/STAT3",4
"GO:0048512","BP","GO:0048512","circadian behavior","4/173","51/21081",0.000810409805096354,0.00204722429361142,0.000797274055705281,"SRD5A1/DRD2/DRD3/MTOR",4
"GO:0048806","BP","GO:0048806","genitalia development","4/173","51/21081",0.000810409805096354,0.00204722429361142,0.000797274055705281,"CYP19A1/SRD5A1/PTPN11/ESR1",4
"GO:0097485","BP","GO:0097485","neuron projection guidance","9/173","298/21081",0.000820332137168454,0.00207105837838905,0.000806556036919542,"MAPK3/PTPN11/SRC/ERBB2/PRKCA/PIK3CA/MAPK1/PTK2/APP",9
"GO:0010948","BP","GO:0010948","negative regulation of cell cycle process","11/173","427/21081",0.000829964562894672,0.00209413267680491,0.000815542125809741,"MDM2/CDK2/PRMT1/CHEK2/CDK4/WEE1/CCND1/MIF/MIF/CDK1/EP300",11
"GO:0002902","BP","GO:0002902","regulation of B cell apoptotic process","3/173","23/21081",0.000852440026268688,0.0021470169956228,0.000836137473119133,"MIF/MIF/IL2",3
"GO:0045723","BP","GO:0045723","positive regulation of fatty acid biosynthetic process","3/173","23/21081",0.000852440026268688,0.0021470169956228,0.000836137473119133,"NR1H3/PTGS2/NR1H2",3
"GO:1901984","BP","GO:1901984","negative regulation of protein acetylation","3/173","23/21081",0.000852440026268688,0.0021470169956228,0.000836137473119133,"GSK3B/SNCA/SIRT1",3
"GO:0046631","BP","GO:0046631","alpha-beta T cell activation","7/173","185/21081",0.000857114116765527,0.00215751059368289,0.00084022411546234,"RORA/IL6/MTOR/RHOA/ABL1/STAT3/IL2",7
"GO:0007622","BP","GO:0007622","rhythmic behavior","4/173","52/21081",0.000872375685105773,0.00219332797989019,0.000854172891302569,"SRD5A1/DRD2/DRD3/MTOR",4
"GO:1900047","BP","GO:1900047","negative regulation of hemostasis","4/173","52/21081",0.000872375685105773,0.00219332797989019,0.000854172891302569,"PLG/SERPINE1/NOS3/F2",4
"GO:0032409","BP","GO:0032409","regulation of transporter activity","9/173","302/21081",0.000901063501930025,0.00226411520975794,0.000881740374760496,"DRD2/PPARG/DRD3/PIM1/NOS1/SNCA/MMP9/APP/CFTR",9
"GO:0002028","BP","GO:0002028","regulation of sodium ion transport","5/173","91/21081",0.000924510343393304,0.00232028614830369,0.000903615668115941,"DRD2/DRD3/NOS3/AKT1/NOS1",5
"GO:0042058","BP","GO:0042058","regulation of epidermal growth factor receptor signaling pathway","5/173","91/21081",0.000924510343393304,0.00232028614830369,0.000903615668115941,"AKT1/EGFR/MMP9/APP/PSEN1",5
"GO:0006998","BP","GO:0006998","nuclear envelope organization","4/173","53/21081",0.000937606915218332,0.00235037863289834,0.000915334929807929,"PRKCB/PRKCA/CDK1/PPP2CA",4
"GO:0071354","BP","GO:0071354","cellular response to interleukin-6","4/173","53/21081",0.000937606915218332,0.00235037863289834,0.000915334929807929,"PTPN11/IL6/SRC/STAT3",4
"GO:0021700","BP","GO:0021700","developmental maturation","9/173","304/21081",0.000943786992471227,0.00236447578479378,0.000920824945484588,"G6PD/PPARG/MTOR/LRRK2/AKR1B1/RHOA/MMP2/APP/CFTR",9
"GO:0021987","BP","GO:0021987","cerebral cortex development","6/173","137/21081",0.000948468824688877,0.00237480497118623,0.000924847559104869,"SRD5A1/GSK3B/CSNK2A2/EGFR/RHOA/PSEN1",6
"GO:0007617","BP","GO:0007617","mating behavior","3/173","24/21081",0.000968368221570839,0.00240760478259479,0.00093762116615402,"HDAC4/MTNR1A/APP",3
"GO:0010310","BP","GO:0010310","regulation of hydrogen peroxide metabolic process","3/173","24/21081",0.000968368221570839,0.00240760478259479,0.00093762116615402,"SNCA/MMP3/STAT3",3
"GO:0010869","BP","GO:0010869","regulation of receptor biosynthetic process","3/173","24/21081",0.000968368221570839,0.00240760478259479,0.00093762116615402,"PPARA/NR1H3/PPARG",3
"GO:0035357","BP","GO:0035357","peroxisome proliferator activated receptor signaling pathway","3/173","24/21081",0.000968368221570839,0.00240760478259479,0.00093762116615402,"FABP5/PPARG/SIRT1",3
"GO:0035812","BP","GO:0035812","renal sodium excretion","3/173","24/21081",0.000968368221570839,0.00240760478259479,0.00093762116615402,"DRD2/AGTR1/DRD3",3
"GO:0044062","BP","GO:0044062","regulation of excretion","3/173","24/21081",0.000968368221570839,0.00240760478259479,0.00093762116615402,"DRD2/AGTR1/DRD3",3
"GO:0051349","BP","GO:0051349","positive regulation of lyase activity","3/173","24/21081",0.000968368221570839,0.00240760478259479,0.00093762116615402,"NOS2/NOS3/NOS1",3
"GO:0060065","BP","GO:0060065","uterus development","3/173","24/21081",0.000968368221570839,0.00240760478259479,0.00093762116615402,"CYP19A1/ESR1/SRC",3
"GO:0060396","BP","GO:0060396","growth hormone receptor signaling pathway","3/173","24/21081",0.000968368221570839,0.00240760478259479,0.00093762116615402,"PTK2/STAT5B/STAT3",3
"GO:1902001","BP","GO:1902001","fatty acid transmembrane transport","3/173","24/21081",0.000968368221570839,0.00240760478259479,0.00093762116615402,"AKT1/ACACA/ACACA",3
"GO:2000637","BP","GO:2000637","positive regulation of gene silencing by miRNA","3/173","24/21081",0.000968368221570839,0.00240760478259479,0.00093762116615402,"IL6/EGFR/STAT3",3
"GO:2000773","BP","GO:2000773","negative regulation of cellular senescence","3/173","24/21081",0.000968368221570839,0.00240760478259479,0.00093762116615402,"TERT/SIRT1/ABL1",3
"GO:0038095","BP","GO:0038095","Fc-epsilon receptor signaling pathway","7/173","189/21081",0.000971184961225893,0.00241178544725238,0.000939249290379343,"MAPK3/MAPK8/IKBKB/PIK3CA/MAPK1/CHUK/MAPK10",7
"GO:0050864","BP","GO:0050864","regulation of B cell activation","7/173","189/21081",0.000971184961225893,0.00241178544725238,0.000939249290379343,"IL6/TLR4/MIF/MIF/STAT5B/CD38/IL2",7
"GO:0043618","BP","GO:0043618","regulation of transcription from RNA polymerase II promoter in response to stress","6/173","138/21081",0.000984947965515042,0.00244310794248302,0.00095144756923197,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/EP300",6
"GO:0071482","BP","GO:0071482","cellular response to light stimulus","6/173","138/21081",0.000984947965515042,0.00244310794248302,0.00095144756923197,"MDM2/PTGS2/PARP1/MC1R/SIRT1/EP300",6
"GO:0022408","BP","GO:0022408","negative regulation of cell-cell adhesion","8/173","246/21081",0.000993797228756384,0.00246361985121696,0.000959435757295974,"PPARA/PLG/IDO1/ERBB2/AKT1/PTK2/ABL1/IL2",8
"GO:0048469","BP","GO:0048469","cell maturation","7/173","190/21081",0.00100148940009881,0.00247979514045444,0.000965735085851628,"G6PD/PPARG/MTOR/LRRK2/AKR1B1/APP/CFTR",7
"GO:0050671","BP","GO:0050671","positive regulation of lymphocyte proliferation","7/173","190/21081",0.00100148940009881,0.00247979514045444,0.000965735085851628,"IL6/TLR4/MIF/MIF/STAT5B/CD38/IL2",7
"GO:0050670","BP","GO:0050670","regulation of lymphocyte proliferation","9/173","307/21081",0.00101094649417878,0.0025017540208303,0.000974286784691192,"IDO1/IL6/ERBB2/TLR4/MIF/MIF/STAT5B/CD38/IL2",9
"GO:0051899","BP","GO:0051899","membrane depolarization","5/173","93/21081",0.00101970316489805,0.00252195503355753,0.000982153896954685,"SRC/PARP1/LRRK2/ABL1/CACNA1B",5
"GO:0002433","BP","GO:0002433","immune response-regulating cell surface receptor signaling pathway involved in phagocytosis","6/173","139/21081",0.00102249668149386,0.00252445578132913,0.000983127791864188,"MAPK3/SRC/PIK3CA/MAPK1/PTK2/ABL1",6
"GO:0010595","BP","GO:0010595","positive regulation of endothelial cell migration","6/173","139/21081",0.00102249668149386,0.00252445578132913,0.000983127791864188,"PTGS2/PRKCA/NOS3/AKT1/SIRT1/ABL1",6
"GO:0038096","BP","GO:0038096","Fc-gamma receptor signaling pathway involved in phagocytosis","6/173","139/21081",0.00102249668149386,0.00252445578132913,0.000983127791864188,"MAPK3/SRC/PIK3CA/MAPK1/PTK2/ABL1",6
"GO:0032946","BP","GO:0032946","positive regulation of mononuclear cell proliferation","7/173","191/21081",0.00103253337581016,0.00254775511836085,0.000992201520125667,"IL6/TLR4/MIF/MIF/STAT5B/CD38/IL2",7
"GO:0010976","BP","GO:0010976","positive regulation of neuron projection development","9/173","308/21081",0.00103417584733647,0.00255032685741883,0.000993203061986696,"CNR1/MTOR/RHOA/MAPT/MAPT/MAPT/IL2/EP300/PSEN1",9
"GO:0048738","BP","GO:0048738","cardiac muscle tissue development","8/173","248/21081",0.00104678677487498,0.00257992865803005,0.00100473123098271,"G6PD/PPARA/MTOR/MAPK1/PIM1/MAPK14/NOX4/CDK1",8
"GO:0032944","BP","GO:0032944","regulation of mononuclear cell proliferation","9/173","309/21081",0.00105783636687013,0.00260414062736453,0.00101416037611749,"IDO1/IL6/ERBB2/TLR4/MIF/MIF/STAT5B/CD38/IL2",9
"GO:1901988","BP","GO:1901988","negative regulation of cell cycle phase transition","9/173","309/21081",0.00105783636687013,0.00260414062736453,0.00101416037611749,"MDM2/CDK2/PRMT1/CHEK2/CDK4/WEE1/CCND1/CDK1/EP300",9
"GO:0051101","BP","GO:0051101","regulation of DNA binding","6/173","140/21081",0.00106113586756497,0.00261075060873396,0.00101673457703479,"MAPK8/PPARG/PARP1/MMP9/EP300/PSEN1",6
"GO:0060401","BP","GO:0060401","cytosolic calcium ion transport","7/173","192/21081",0.00106432949508478,0.00261709260683752,0.00101920441415283,"DRD2/HTR2A/NOS1/SNCA/F2/ABL1/PSEN2",7
"GO:0051972","BP","GO:0051972","regulation of telomerase activity","4/173","55/21081",0.00107823666782066,0.00264975569784266,0.00103192477660593,"MAPK3/PPARG/SRC/MAPK1",4
"GO:0014829","BP","GO:0014829","vascular associated smooth muscle contraction","3/173","25/21081",0.0010938143335669,0.00267874184629727,0.00104321318511583,"HTR2A/RHOA/CD38",3
"GO:0022410","BP","GO:0022410","circadian sleep/wake cycle process","3/173","25/21081",0.0010938143335669,0.00267874184629727,0.00104321318511583,"SRD5A1/DRD2/DRD3",3
"GO:0034643","BP","GO:0034643","establishment of mitochondrion localization, microtubule-mediated","3/173","25/21081",0.0010938143335669,0.00267874184629727,0.00104321318511583,"MAPT/MAPT/MAPT",3
"GO:0047497","BP","GO:0047497","mitochondrion transport along microtubule","3/173","25/21081",0.0010938143335669,0.00267874184629727,0.00104321318511583,"MAPT/MAPT/MAPT",3
"GO:0060148","BP","GO:0060148","positive regulation of posttranscriptional gene silencing","3/173","25/21081",0.0010938143335669,0.00267874184629727,0.00104321318511583,"IL6/EGFR/STAT3",3
"GO:0071378","BP","GO:0071378","cellular response to growth hormone stimulus","3/173","25/21081",0.0010938143335669,0.00267874184629727,0.00104321318511583,"PTK2/STAT5B/STAT3",3
"GO:0007193","BP","GO:0007193","adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway","5/173","95/21081",0.00112198722449645,0.00274615421479574,0.00106946635757241,"DRD2/DRD3/HTR1A/HTR4/MTNR1A",5
"GO:0098657","BP","GO:0098657","import into cell","8/173","251/21081",0.0011304876553324,0.00276536675158742,0.00107694851630611,"SLC6A3/SLC6A3/DRD2/DRD3/AKT1/NOS1/SNCA/PSEN1",8
"GO:0038094","BP","GO:0038094","Fc-gamma receptor signaling pathway","6/173","142/21081",0.00114177004766499,0.00279135841917638,0.00108707074976038,"MAPK3/SRC/PIK3CA/MAPK1/PTK2/ABL1",6
"GO:0050819","BP","GO:0050819","negative regulation of coagulation","4/173","56/21081",0.00115382076126156,0.00281434237347897,0.00109602165490554,"PLG/SERPINE1/NOS3/F2",4
"GO:0050832","BP","GO:0050832","defense response to fungus","4/173","56/21081",0.00115382076126156,0.00281434237347897,0.00109602165490554,"MPO/CTSG/ELANE/ELANE",4
"GO:0051496","BP","GO:0051496","positive regulation of stress fiber assembly","4/173","56/21081",0.00115382076126156,0.00281434237347897,0.00109602165490554,"MTOR/RHOA/ABL1/NOX4",4
"GO:2000107","BP","GO:2000107","negative regulation of leukocyte apoptotic process","4/173","56/21081",0.00115382076126156,0.00281434237347897,0.00109602165490554,"IDO1/MIF/MIF/IL2",4
"GO:0043409","BP","GO:0043409","negative regulation of MAPK cascade","7/173","195/21081",0.00116435833364768,0.0028384156968841,0.0011053968055646,"HMGCR/IGF1R/CSK/AKT1/TLR4/ABL1/PPP2CA",7
"GO:0030534","BP","GO:0030534","adult behavior","6/173","144/21081",0.0012270208994976,0.00298077030766367,0.00116083559565651,"PPARA/DRD2/DRD3/HTR2A/CHRNA3/APP",6
"GO:0015874","BP","GO:0015874","norepinephrine transport","3/173","26/21081",0.00122906791692793,0.00298077030766367,0.00116083559565651,"SLC6A3/SLC6A3/SNCA",3
"GO:0034063","BP","GO:0034063","stress granule assembly","3/173","26/21081",0.00122906791692793,0.00298077030766367,0.00116083559565651,"MAPT/MAPT/MAPT",3
"GO:0042136","BP","GO:0042136","neurotransmitter biosynthetic process","3/173","26/21081",0.00122906791692793,0.00298077030766367,0.00116083559565651,"SLC6A3/SLC6A3/NOS1",3
"GO:0042430","BP","GO:0042430","indole-containing compound metabolic process","3/173","26/21081",0.00122906791692793,0.00298077030766367,0.00116083559565651,"SRD5A1/IDO1/HTR1A",3
"GO:0060259","BP","GO:0060259","regulation of feeding behavior","3/173","26/21081",0.00122906791692793,0.00298077030766367,0.00116083559565651,"CNR1/MTOR/STAT3",3
"GO:0060330","BP","GO:0060330","regulation of response to interferon-gamma","3/173","26/21081",0.00122906791692793,0.00298077030766367,0.00116083559565651,"NR1H3/PPARG/NR1H2",3
"GO:0060334","BP","GO:0060334","regulation of interferon-gamma-mediated signaling pathway","3/173","26/21081",0.00122906791692793,0.00298077030766367,0.00116083559565651,"NR1H3/PPARG/NR1H2",3
"GO:1900452","BP","GO:1900452","regulation of long-term synaptic depression","3/173","26/21081",0.00122906791692793,0.00298077030766367,0.00116083559565651,"MAPT/MAPT/MAPT",3
"GO:2000106","BP","GO:2000106","regulation of leukocyte apoptotic process","5/173","97/21081",0.00123168294823826,0.00298529476892347,0.0011625976085389,"IDO1/MIF/MIF/SIRT1/IL2",5
"GO:0035065","BP","GO:0035065","regulation of histone acetylation","4/173","57/21081",0.00123304126134636,0.00298529476892347,0.0011625976085389,"MAPK3/NOS1/SNCA/SIRT1",4
"GO:0070741","BP","GO:0070741","response to interleukin-6","4/173","57/21081",0.00123304126134636,0.00298529476892347,0.0011625976085389,"PTPN11/IL6/SRC/STAT3",4
"GO:0016241","BP","GO:0016241","regulation of macroautophagy","7/173","197/21081",0.00123504070011154,0.00298843276467763,0.0011638196742449,"MAPK3/MAPK8/MTOR/PIK3CA/AKT1/LRRK2/SIRT1",7
"GO:0006457","BP","GO:0006457","protein folding","8/173","255/21081",0.00125031778091108,0.00302367686459373,0.00117754518862428,"CSNK2A1/CSNK2A2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/VCP",8
"GO:0043620","BP","GO:0043620","regulation of DNA-templated transcription in response to stress","6/173","145/21081",0.00127143151028209,0.00307298776290593,0.00119674889776867,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/EP300",6
"GO:0045017","BP","GO:0045017","glycerolipid biosynthetic process","9/173","318/21081",0.00129117471028798,0.00311893197499353,0.00121464147965214,"NR1H4/FABP5/NR1H3/NR1H2/HTR2A/CSNK2A1/CSNK2A2/PIK3CA/PIK3CG",9
"GO:0016579","BP","GO:0016579","protein deubiquitination","9/173","320/21081",0.00134828373237231,0.00325503271525566,0.00126764475316344,"ESR1/MDM2/CCNA2/RHOA/CDK1/CFTR/OGT/VCP/EP300",9
"GO:0032640","BP","GO:0032640","tumor necrosis factor production","6/173","147/21081",0.00136393229372151,0.00329094168996178,0.00128162919736407,"PTPN11/TLR4/MIF/MIF/MC1R/APP",6
"GO:0006525","BP","GO:0006525","arginine metabolic process","3/173","27/21081",0.00137440957825317,0.00330870611784573,0.00128854740242373,"NOS2/NOS3/NOS1",3
"GO:0035640","BP","GO:0035640","exploration behavior","3/173","27/21081",0.00137440957825317,0.00330870611784573,0.00128854740242373,"HTR1A/LRRK2/DPP4",3
"GO:0042730","BP","GO:0042730","fibrinolysis","3/173","27/21081",0.00137440957825317,0.00330870611784573,0.00128854740242373,"PLG/SERPINE1/F2",3
"GO:1902175","BP","GO:1902175","regulation of oxidative stress-induced intrinsic apoptotic signaling pathway","3/173","27/21081",0.00137440957825317,0.00330870611784573,0.00128854740242373,"AKT1/PARP1/SIRT1",3
"GO:0051783","BP","GO:0051783","regulation of nuclear division","7/173","201/21081",0.00138647185503502,0.00333585442358085,0.00129912007874772,"DRD3/INSR/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",7
"GO:0060828","BP","GO:0060828","regulation of canonical Wnt signaling pathway","9/173","322/21081",0.00140741357176468,0.00338432386328699,0.00131799608900847,"XIAP/SRC/GSK3B/LRRK2/EGFR/PPP1CA/MAPK14/VCP/PSEN1",9
"GO:0019319","BP","GO:0019319","hexose biosynthetic process","5/173","100/21081",0.00141083293531036,0.00339062734283581,0.0013204509254036,"PPARA/AKR1B1/SIRT1/OGT/EP300",5
"GO:0072329","BP","GO:0072329","monocarboxylic acid catabolic process","6/173","149/21081",0.00146148645791522,0.00350839319756032,0.00136631383398318,"PPARA/FABP1/CNR1/MTOR/CYP26A1/AKT1",6
"GO:0097553","BP","GO:0097553","calcium ion transmembrane import into cytosol","6/173","149/21081",0.00146148645791522,0.00350839319756032,0.00136631383398318,"DRD2/HTR2A/NOS1/SNCA/F2/ABL1",6
"GO:0045744","BP","GO:0045744","negative regulation of G protein-coupled receptor signaling pathway","4/173","60/21081",0.00149344577234738,0.00357904742622899,0.0013938295212575,"DRD2/DRD3/SNCA/CXCL8",4
"GO:0060043","BP","GO:0060043","regulation of cardiac muscle cell proliferation","4/173","60/21081",0.00149344577234738,0.00357904742622899,0.0013938295212575,"MAPK1/PIM1/MAPK14/CDK1",4
"GO:0071827","BP","GO:0071827","plasma lipoprotein particle organization","4/173","60/21081",0.00149344577234738,0.00357904742622899,0.0013938295212575,"AGTR1/NR1H2/MPO/CETP",4
"GO:0071706","BP","GO:0071706","tumor necrosis factor superfamily cytokine production","6/173","150/21081",0.00151221432656897,0.00362198346876638,0.00141055059714379,"PTPN11/TLR4/MIF/MIF/MC1R/APP",6
"GO:0036315","BP","GO:0036315","cellular response to sterol","3/173","28/21081",0.00153011113023976,0.00365660415769894,0.00142403332942804,"CES1/CES1/RORA",3
"GO:0042745","BP","GO:0042745","circadian sleep/wake cycle","3/173","28/21081",0.00153011113023976,0.00365660415769894,0.00142403332942804,"SRD5A1/DRD2/DRD3",3
"GO:0043691","BP","GO:0043691","reverse cholesterol transport","3/173","28/21081",0.00153011113023976,0.00365660415769894,0.00142403332942804,"CES1/CES1/CETP",3
"GO:0097066","BP","GO:0097066","response to thyroid hormone","3/173","28/21081",0.00153011113023976,0.00365660415769894,0.00142403332942804,"AKR1B1/CTSB/CTSB",3
"GO:0021953","BP","GO:0021953","central nervous system neuron differentiation","7/173","205/21081",0.00155204536230512,0.00370693689962589,0.00144363498686054,"RORA/DRD2/PTK2/MAPT/MAPT/MAPT/PSEN1",7
"GO:0071333","BP","GO:0071333","cellular response to glucose stimulus","6/173","151/21081",0.00156427273843093,0.00373404205932193,0.00145419086032728,"NR1H4/HMGCR/IGF1R/PIK3CA/NOX4/CFTR",6
"GO:0030520","BP","GO:0030520","intracellular estrogen receptor signaling pathway","4/173","61/21081",0.00158813547212322,0.00378674950676294,0.00147471732658616,"ESR1/ESR2/SRC/PARP1",4
"GO:0048008","BP","GO:0048008","platelet-derived growth factor receptor signaling pathway","4/173","61/21081",0.00158813547212322,0.00378674950676294,0.00147471732658616,"PTPN11/SRC/SNCA/ABL1",4
"GO:0002040","BP","GO:0002040","sprouting angiogenesis","7/173","206/21081",0.0015957517538015,0.00380277577223926,0.00148095861910793,"ALOX5/ALOX5/PTGS2/AGTR1/AKT1/RHOA/ABL1",7
"GO:0031058","BP","GO:0031058","positive regulation of histone modification","5/173","103/21081",0.00160849534940076,0.00382884971406378,0.00149111289356214,"MAPK3/NOS1/LRRK2/SIRT1/OGT",5
"GO:0060291","BP","GO:0060291","long-term synaptic potentiation","5/173","103/21081",0.00160849534940076,0.00382884971406378,0.00149111289356214,"DRD2/GSK3B/MAPK1/ABL1/APP",5
"GO:0071331","BP","GO:0071331","cellular response to hexose stimulus","6/173","153/21081",0.00167247204623758,0.00397891026005795,0.00154955269445717,"NR1H4/HMGCR/IGF1R/PIK3CA/NOX4/CFTR",6
"GO:0061097","BP","GO:0061097","regulation of protein tyrosine kinase activity","5/173","104/21081",0.00167868998587022,0.00399146824284419,0.0015544432938403,"SRC/ACE/NOX4/APP/PSEN1",5
"GO:1902275","BP","GO:1902275","regulation of chromatin organization","7/173","208/21081",0.00168603831832662,0.00399539162745886,0.00155597122254532,"MAPK3/MAPK8/NOS1/LRRK2/SNCA/SIRT1/OGT",7
"GO:0032760","BP","GO:0032760","positive regulation of tumor necrosis factor production","4/173","62/21081",0.00168692223574045,0.00399539162745886,0.00155597122254532,"PTPN11/TLR4/MIF/MIF",4
"GO:0042572","BP","GO:0042572","retinol metabolic process","4/173","62/21081",0.00168692223574045,0.00399539162745886,0.00155597122254532,"AKR1B10/TTR/AKR1B1/CYP1B1",4
"GO:0070228","BP","GO:0070228","regulation of lymphocyte apoptotic process","4/173","62/21081",0.00168692223574045,0.00399539162745886,0.00155597122254532,"IDO1/MIF/MIF/IL2",4
"GO:1900271","BP","GO:1900271","regulation of long-term synaptic potentiation","4/173","62/21081",0.00168692223574045,0.00399539162745886,0.00155597122254532,"DRD2/GSK3B/ABL1/APP",4
"GO:1902041","BP","GO:1902041","regulation of extrinsic apoptotic signaling pathway via death domain receptors","4/173","62/21081",0.00168692223574045,0.00399539162745886,0.00155597122254532,"SERPINE1/BCL2L1/GSK3B/NOS3",4
"GO:2000059","BP","GO:2000059","negative regulation of ubiquitin-dependent protein catabolic process","4/173","62/21081",0.00168692223574045,0.00399539162745886,0.00155597122254532,"CSNK2A1/CSNK2A2/OGT/PSEN1",4
"GO:0001783","BP","GO:0001783","B cell apoptotic process","3/173","29/21081",0.00169643574373135,0.00400230731544393,0.00155866447829901,"MIF/MIF/IL2",3
"GO:0033598","BP","GO:0033598","mammary gland epithelial cell proliferation","3/173","29/21081",0.00169643574373135,0.00400230731544393,0.00155866447829901,"ESR1/MAPK1/CCND1",3
"GO:0051654","BP","GO:0051654","establishment of mitochondrion localization","3/173","29/21081",0.00169643574373135,0.00400230731544393,0.00155866447829901,"MAPT/MAPT/MAPT",3
"GO:0051953","BP","GO:0051953","negative regulation of amine transport","3/173","29/21081",0.00169643574373135,0.00400230731544393,0.00155866447829901,"DRD2/CNR1/SNCA",3
"GO:0071880","BP","GO:0071880","adenylate cyclase-activating adrenergic receptor signaling pathway","3/173","29/21081",0.00169643574373135,0.00400230731544393,0.00155866447829901,"DRD2/DRD3/NOS1",3
"GO:1905208","BP","GO:1905208","negative regulation of cardiocyte differentiation","3/173","29/21081",0.00169643574373135,0.00400230731544393,0.00155866447829901,"G6PD/PPARA/EGFR",3
"GO:1990776","BP","GO:1990776","response to angiotensin","3/173","29/21081",0.00169643574373135,0.00400230731544393,0.00155866447829901,"PTGS2/AGTR1/SRC",3
"GO:0006650","BP","GO:0006650","glycerophospholipid metabolic process","10/173","398/21081",0.0017126630247092,0.00403834916314617,0.00157270066875569,"NR1H4/FABP5/NR1H3/NR1H2/HTR2A/CSNK2A1/CSNK2A2/PIK3CA/PIK3CG/CETP",10
"GO:0071326","BP","GO:0071326","cellular response to monosaccharide stimulus","6/173","154/21081",0.00172865869135169,0.00407380520219265,0.00158650872102336,"NR1H4/HMGCR/IGF1R/PIK3CA/NOX4/CFTR",6
"GO:0046390","BP","GO:0046390","ribose phosphate biosynthetic process","7/173","209/21081",0.00173264689721671,0.00408094050236906,0.00158928750287353,"G6PD/PARP1/STAT3/FASN/ACACA/ACACA/VCP",7
"GO:0044264","BP","GO:0044264","cellular polysaccharide metabolic process","5/173","105/21081",0.00175110774808143,0.00412213674326759,0.0016053310278373,"GSK3B/MTOR/AKT1/INSR/PPP1CA",5
"GO:0043388","BP","GO:0043388","positive regulation of DNA binding","4/173","63/21081",0.00178989738842959,0.00420878472796754,0.00163907534710705,"PPARG/PARP1/MMP9/EP300",4
"GO:2000756","BP","GO:2000756","regulation of peptidyl-lysine acetylation","4/173","63/21081",0.00178989738842959,0.00420878472796754,0.00163907534710705,"MAPK3/NOS1/SNCA/SIRT1",4
"GO:0030516","BP","GO:0030516","regulation of axon extension","5/173","106/21081",0.00182579056502523,0.00428843787219028,0.00167009558535956,"GSK3B/ABL1/MAPT/MAPT/MAPT",5
"GO:0050709","BP","GO:0050709","negative regulation of protein secretion","5/173","106/21081",0.00182579056502523,0.00428843787219028,0.00167009558535956,"HMGCR/PTPN11/NR1H3/DRD2/DRD3",5
"GO:0043433","BP","GO:0043433","negative regulation of DNA-binding transcription factor activity","7/173","211/21081",0.00182886631965805,0.00429328894598181,0.00167198479470919,"NR1H4/ESR1/PIM1/CHUK/HDAC4/SIRT1/CYP1B1",7
"GO:0060078","BP","GO:0060078","regulation of postsynaptic membrane potential","6/173","156/21081",0.00184532127074432,0.00432713580540431,0.00168516616568495,"DRD2/GSK3B/AKT1/CHRNA3/LRRK2/APP",6
"GO:1903670","BP","GO:1903670","regulation of sprouting angiogenesis","6/173","156/21081",0.00184532127074432,0.00432713580540431,0.00168516616568495,"ALOX5/ALOX5/PTGS2/AGTR1/RHOA/ABL1",6
"GO:0001782","BP","GO:0001782","B cell homeostasis","3/173","30/21081",0.00187363809767154,0.00438869254520748,0.00170913891344494,"MIF/MIF/ABL1",3
"GO:2000191","BP","GO:2000191","regulation of fatty acid transport","3/173","30/21081",0.00187363809767154,0.00438869254520748,0.00170913891344494,"AKT1/MIF/MIF",3
"GO:0071825","BP","GO:0071825","protein-lipid complex subunit organization","4/173","64/21081",0.00189715190390854,0.00443887579279041,0.00172868235157908,"AGTR1/NR1H2/MPO/CETP",4
"GO:1903557","BP","GO:1903557","positive regulation of tumor necrosis factor superfamily cytokine production","4/173","64/21081",0.00189715190390854,0.00443887579279041,0.00172868235157908,"PTPN11/TLR4/MIF/MIF",4
"GO:0007631","BP","GO:0007631","feeding behavior","5/173","107/21081",0.00190278048741083,0.00444714757481223,0.0017319037265994,"DRD2/CNR1/MTOR/STAT3/APP",5
"GO:0048709","BP","GO:0048709","oligodendrocyte differentiation","5/173","107/21081",0.00190278048741083,0.00444714757481223,0.0017319037265994,"PPARG/DRD3/ERBB2/CSK/MTOR",5
"GO:0070646","BP","GO:0070646","protein modification by small protein removal","9/173","337/21081",0.001920658936534,0.00448417586921803,0.00174632408031877,"ESR1/MDM2/CCNA2/RHOA/CDK1/CFTR/OGT/VCP/EP300",9
"GO:0016358","BP","GO:0016358","dendrite development","8/173","273/21081",0.00192073430971448,0.00448417586921803,0.00174632408031877,"GSK3B/MTOR/CHRNA3/LRRK2/RHOA/APP/IL2/PSEN1",8
"GO:0043524","BP","GO:0043524","negative regulation of neuron apoptotic process","6/173","158/21081",0.00196785803974908,0.00459166875941451,0.00178818627040409,"BCL2L1/TERT/PIK3CA/RHOA/C5AR1/PSEN1",6
"GO:0001889","BP","GO:0001889","liver development","6/173","159/21081",0.00203138785160377,0.00473730350245028,0.00184490248005149,"SRD5A1/IL6/CSNK2A2/PIK3CA/EGFR/CCND1",6
"GO:0002438","BP","GO:0002438","acute inflammatory response to antigenic stimulus","3/173","31/21081",0.00206196452698734,0.00480070535625709,0.00186959379173704,"CNR1/ELANE/ELANE",3
"GO:0019098","BP","GO:0019098","reproductive behavior","3/173","31/21081",0.00206196452698734,0.00480070535625709,0.00186959379173704,"HDAC4/MTNR1A/APP",3
"GO:0035666","BP","GO:0035666","TRIF-dependent toll-like receptor signaling pathway","3/173","31/21081",0.00206196452698734,0.00480070535625709,0.00186959379173704,"IKBKB/CHUK/TLR4",3
"GO:0009141","BP","GO:0009141","nucleoside triphosphate metabolic process","5/173","109/21081",0.00206385040170366,0.00480246459848787,0.00187027891363242,"PARP1/LRRK2/RHOA/STAT3/VCP",5
"GO:0032535","BP","GO:0032535","regulation of cellular component size","10/173","409/21081",0.00208989140226784,0.00486039877845432,0.00189284088633367,"GSK3B/MTOR/CDK4/AKT1/PPP1CA/RHOA/ABL1/MAPT/MAPT/MAPT",10
"GO:0098656","BP","GO:0098656","anion transmembrane transport","9/173","342/21081",0.0021216322237771,0.00493093076108613,0.00192030896593066,"SLC22A6/MTOR/AKT1/ABCC1/ABCC1/CFTR/ACACA/ACACA/PSEN1",9
"GO:0006940","BP","GO:0006940","regulation of smooth muscle contraction","4/173","66/21081",0.00212486096106112,0.00493093076108613,0.00192030896593066,"PTGS2/TACR1/CHRNA3/RHOA",4
"GO:0032233","BP","GO:0032233","positive regulation of actin filament bundle assembly","4/173","66/21081",0.00212486096106112,0.00493093076108613,0.00192030896593066,"MTOR/RHOA/ABL1/NOX4",4
"GO:0045747","BP","GO:0045747","positive regulation of Notch signaling pathway","4/173","66/21081",0.00212486096106112,0.00493093076108613,0.00192030896593066,"SRC/NOS3/STAT3/EP300",4
"GO:0090277","BP","GO:0090277","positive regulation of peptide hormone secretion","5/173","110/21081",0.00214801501641981,0.00498194094146712,0.00194017444599629,"NR1H4/DRD2/EGFR/CD38/CFTR",5
"GO:0044282","BP","GO:0044282","small molecule catabolic process","11/173","483/21081",0.0022076331140277,0.00511742122286072,0.00199293608708849,"AKR1B10/PPARA/FABP1/NOS2/IDO1/CNR1/MTOR/NOS3/CYP26A1/AKT1/NOS1",11
"GO:0061008","BP","GO:0061008","hepaticobiliary system development","6/173","162/21081",0.00223130692066053,0.00516947824748452,0.00201320925172379,"SRD5A1/IL6/CSNK2A2/PIK3CA/EGFR/CCND1",6
"GO:0034308","BP","GO:0034308","primary alcohol metabolic process","5/173","111/21081",0.00223465596298907,0.00517441590558069,0.00201513218059304,"AKR1B10/TTR/AKR1B1/AKR1C1/CYP1B1",5
"GO:0030857","BP","GO:0030857","negative regulation of epithelial cell differentiation","4/173","67/21081",0.00224549539685234,0.00519102825964397,0.00202160172032065,"GSK3B/XDH/CCND1/MMP9",4
"GO:0051893","BP","GO:0051893","regulation of focal adhesion assembly","4/173","67/21081",0.00224549539685234,0.00519102825964397,0.00202160172032065,"SRC/PTK2/RHOA/ABL1",4
"GO:0090109","BP","GO:0090109","regulation of cell-substrate junction assembly","4/173","67/21081",0.00224549539685234,0.00519102825964397,0.00202160172032065,"SRC/PTK2/RHOA/ABL1",4
"GO:0036336","BP","GO:0036336","dendritic cell migration","3/173","32/21081",0.00226165316842812,0.00521986111496529,0.00203283043012608,"ALOX5/ALOX5/PIK3CG",3
"GO:0071295","BP","GO:0071295","cellular response to vitamin","3/173","32/21081",0.00226165316842812,0.00521986111496529,0.00203283043012608,"MDM2/PPARG/PIM1",3
"GO:1902473","BP","GO:1902473","regulation of protein localization to synapse","3/173","32/21081",0.00226165316842812,0.00521986111496529,0.00203283043012608,"MAPT/MAPT/MAPT",3
"GO:0010977","BP","GO:0010977","negative regulation of neuron projection development","6/173","163/21081",0.00230113595793577,0.00530810352077583,0.00206719568311048,"MDM2/LRRK2/PTK2/RHOA/CD38/PSEN1",6
"GO:0002792","BP","GO:0002792","negative regulation of peptide secretion","5/173","112/21081",0.00232381575589715,0.00535170360260542,0.00208417536344049,"HMGCR/PTPN11/NR1H3/DRD2/DRD3",5
"GO:0043266","BP","GO:0043266","regulation of potassium ion transport","5/173","112/21081",0.00232381575589715,0.00535170360260542,0.00208417536344049,"DRD2/DRD3/HTR2A/NOS3/NOS1",5
"GO:0090342","BP","GO:0090342","regulation of cell aging","5/173","112/21081",0.00232381575589715,0.00535170360260542,0.00208417536344049,"TERT/MIF/MIF/SIRT1/ABL1",5
"GO:0031122","BP","GO:0031122","cytoplasmic microtubule organization","4/173","68/21081",0.00237076892175135,0.00545392374040145,0.00212398412503526,"RHOA/MAPT/MAPT/MAPT",4
"GO:1904356","BP","GO:1904356","regulation of telomere maintenance via telomere lengthening","4/173","68/21081",0.00237076892175135,0.00545392374040145,0.00212398412503526,"MAPK3/SRC/MAPK1/PARP1",4
"GO:0034766","BP","GO:0034766","negative regulation of ion transmembrane transport","5/173","113/21081",0.00241553697375115,0.0055539050873748,0.00216292100862201,"DRD2/DRD3/MTOR/AKT1/MMP9",5
"GO:1901605","BP","GO:1901605","alpha-amino acid metabolic process","7/173","222/21081",0.00243452164215236,0.00559452810032741,0.00217874129484701,"NR1H4/NOS2/IDO1/NOS3/NOS1/NOX4/TYR",7
"GO:0033032","BP","GO:0033032","regulation of myeloid cell apoptotic process","3/173","33/21081",0.00247293410438478,0.00565831826038283,0.00220358382909212,"MIF/MIF/SIRT1",3
"GO:0034104","BP","GO:0034104","negative regulation of tissue remodeling","3/173","33/21081",0.00247293410438478,0.00565831826038283,0.00220358382909212,"IL6/CSK/CD38",3
"GO:0060325","BP","GO:0060325","face morphogenesis","3/173","33/21081",0.00247293410438478,0.00565831826038283,0.00220358382909212,"PTPN11/MMP2/EP300",3
"GO:0061050","BP","GO:0061050","regulation of cell growth involved in cardiac muscle cell development","3/173","33/21081",0.00247293410438478,0.00565831826038283,0.00220358382909212,"G6PD/PPARA/MTOR",3
"GO:0061081","BP","GO:0061081","positive regulation of myeloid leukocyte cytokine production involved in immune response","3/173","33/21081",0.00247293410438478,0.00565831826038283,0.00220358382909212,"TLR4/MIF/MIF",3
"GO:0071280","BP","GO:0071280","cellular response to copper ion","3/173","33/21081",0.00247293410438478,0.00565831826038283,0.00220358382909212,"BACE1/SNCA/APP",3
"GO:0071875","BP","GO:0071875","adrenergic receptor signaling pathway","3/173","33/21081",0.00247293410438478,0.00565831826038283,0.00220358382909212,"DRD2/DRD3/NOS1",3
"GO:0090022","BP","GO:0090022","regulation of neutrophil chemotaxis","3/173","33/21081",0.00247293410438478,0.00565831826038283,0.00220358382909212,"CXCL8/DPP4/C5AR1",3
"GO:0001655","BP","GO:0001655","urogenital system development","9/173","350/21081",0.00247778168323925,0.00566635865020645,0.00220671509039267,"CYP19A1/SRD5A1/ESR1/AGTR1/CYP26A1/LRRK2/AKR1B1/ACE/MMP9",9
"GO:0051651","BP","GO:0051651","maintenance of location in cell","7/173","223/21081",0.00249641556211118,0.00570590087327079,0.00222211447220564,"DRD2/HTR2A/AKT1/NOS1/SNCA/F2/ABL1",7
"GO:0016573","BP","GO:0016573","histone acetylation","6/173","167/21081",0.00259704036988592,0.00592951345064227,0.00230919848494621,"MAPK3/NOS1/SNCA/SIRT1/OGT/EP300",6
"GO:0046661","BP","GO:0046661","male sex differentiation","6/173","167/21081",0.00259704036988592,0.00592951345064227,0.00230919848494621,"SRD5A1/ESR1/BCL2L1/CCND1/INSR/STAT5B",6
"GO:0030038","BP","GO:0030038","contractile actin filament bundle assembly","5/173","115/21081",0.0026068342628568,0.00594548512231805,0.00231541851637759,"SRC/MTOR/RHOA/ABL1/NOX4",5
"GO:0043149","BP","GO:0043149","stress fiber assembly","5/173","115/21081",0.0026068342628568,0.00594548512231805,0.00231541851637759,"SRC/MTOR/RHOA/ABL1/NOX4",5
"GO:0022898","BP","GO:0022898","regulation of transmembrane transporter activity","8/173","287/21081",0.00261633295752268,0.00596394782001817,0.00232260865666685,"DRD2/DRD3/PIM1/NOS1/SNCA/MMP9/APP/CFTR",8
"GO:0009749","BP","GO:0009749","response to glucose","7/173","225/21081",0.00262383433892727,0.00597784027136836,0.00232801895346052,"NR1H4/HMGCR/IGF1R/PIK3CA/RHOA/NOX4/CFTR",7
"GO:0060038","BP","GO:0060038","cardiac muscle cell proliferation","4/173","70/21081",0.00263558763990921,0.00599818526083248,0.0023359421362373,"MAPK1/PIM1/MAPK14/CDK1",4
"GO:0150116","BP","GO:0150116","regulation of cell-substrate junction organization","4/173","70/21081",0.00263558763990921,0.00599818526083248,0.0023359421362373,"SRC/PTK2/RHOA/ABL1",4
"GO:0060402","BP","GO:0060402","calcium ion transport into cytosol","6/173","168/21081",0.00267528483273343,0.00608527047873894,0.00236985673225344,"DRD2/HTR2A/NOS1/SNCA/F2/ABL1",6
"GO:0007202","BP","GO:0007202","activation of phospholipase C activity","3/173","34/21081",0.00269602950471367,0.0061095623282818,0.00237931698605467,"HTR2A/EGFR/C5AR1",3
"GO:0008209","BP","GO:0008209","androgen metabolic process","3/173","34/21081",0.00269602950471367,0.0061095623282818,0.00237931698605467,"CYP19A1/SRD5A1/ESR1",3
"GO:0009065","BP","GO:0009065","glutamine family amino acid catabolic process","3/173","34/21081",0.00269602950471367,0.0061095623282818,0.00237931698605467,"NOS2/NOS3/NOS1",3
"GO:0120255","BP","GO:0120255","olefinic compound biosynthetic process","3/173","34/21081",0.00269602950471367,0.0061095623282818,0.00237931698605467,"CYP19A1/ALOX5/ALOX5",3
"GO:1902745","BP","GO:1902745","positive regulation of lamellipodium organization","3/173","34/21081",0.00269602950471367,0.0061095623282818,0.00237931698605467,"SRC/MTOR/HDAC4",3
"GO:1905048","BP","GO:1905048","regulation of metallopeptidase activity","3/173","34/21081",0.00269602950471367,0.0061095623282818,0.00237931698605467,"MAPK3/STAT3/MAPK14",3
"GO:2000352","BP","GO:2000352","negative regulation of endothelial cell apoptotic process","3/173","34/21081",0.00269602950471367,0.0061095623282818,0.00237931698605467,"SERPINE1/TERT/ABL1",3
"GO:0005976","BP","GO:0005976","polysaccharide metabolic process","5/173","116/21081",0.00270649572742092,0.00612674498977704,0.00238600862715178,"GSK3B/MTOR/AKT1/INSR/PPP1CA",5
"GO:0035710","BP","GO:0035710","CD4-positive, alpha-beta T cell activation","5/173","116/21081",0.00270649572742092,0.00612674498977704,0.00238600862715178,"RORA/IL6/MTOR/STAT3/IL2",5
"GO:2000378","BP","GO:2000378","negative regulation of reactive oxygen species metabolic process","4/173","71/21081",0.00277530866245529,0.0062791727938086,0.00244537033651686,"G6PD/MMP3/RHOA/STAT3",4
"GO:1905269","BP","GO:1905269","positive regulation of chromatin organization","5/173","117/21081",0.00280888938500952,0.00635176742783686,0.00247364169812328,"MAPK3/NOS1/LRRK2/SIRT1/OGT",5
"GO:0021537","BP","GO:0021537","telencephalon development","8/173","291/21081",0.0028474600893019,0.00643556272310839,0.00250627506180436,"SRD5A1/DRD2/GSK3B/CSNK2A2/LRRK2/EGFR/RHOA/PSEN1",8
"GO:0007220","BP","GO:0007220","Notch receptor processing","2/173","10/21081",0.00288553842108801,0.00645977489525972,0.00251570428592443,"PSEN2/PSEN1",2
"GO:0008300","BP","GO:0008300","isoprenoid catabolic process","2/173","10/21081",0.00288553842108801,0.00645977489525972,0.00251570428592443,"AKR1B10/CYP26A1",2
"GO:0014041","BP","GO:0014041","regulation of neuron maturation","2/173","10/21081",0.00288553842108801,0.00645977489525972,0.00251570428592443,"MTOR/LRRK2",2
"GO:0032000","BP","GO:0032000","positive regulation of fatty acid beta-oxidation","2/173","10/21081",0.00288553842108801,0.00645977489525972,0.00251570428592443,"PPARA/FABP1",2
"GO:0032070","BP","GO:0032070","regulation of deoxyribonuclease activity","2/173","10/21081",0.00288553842108801,0.00645977489525972,0.00251570428592443,"AKT1/SIRT1",2
"GO:0035672","BP","GO:0035672","oligopeptide transmembrane transport","2/173","10/21081",0.00288553842108801,0.00645977489525972,0.00251570428592443,"ABCC1/ABCC1",2
"GO:0042428","BP","GO:0042428","serotonin metabolic process","2/173","10/21081",0.00288553842108801,0.00645977489525972,0.00251570428592443,"SRD5A1/HTR1A",2
"GO:0048755","BP","GO:0048755","branching morphogenesis of a nerve","2/173","10/21081",0.00288553842108801,0.00645977489525972,0.00251570428592443,"DRD2/LRRK2",2
"GO:0051121","BP","GO:0051121","hepoxilin metabolic process","2/173","10/21081",0.00288553842108801,0.00645977489525972,0.00251570428592443,"ALOX5/ALOX5",2
"GO:0051122","BP","GO:0051122","hepoxilin biosynthetic process","2/173","10/21081",0.00288553842108801,0.00645977489525972,0.00251570428592443,"ALOX5/ALOX5",2
"GO:0070391","BP","GO:0070391","response to lipoteichoic acid","2/173","10/21081",0.00288553842108801,0.00645977489525972,0.00251570428592443,"TLR4/MAPK14",2
"GO:0071104","BP","GO:0071104","response to interleukin-9","2/173","10/21081",0.00288553842108801,0.00645977489525972,0.00251570428592443,"STAT5B/STAT3",2
"GO:0071223","BP","GO:0071223","cellular response to lipoteichoic acid","2/173","10/21081",0.00288553842108801,0.00645977489525972,0.00251570428592443,"TLR4/MAPK14",2
"GO:0071394","BP","GO:0071394","cellular response to testosterone stimulus","2/173","10/21081",0.00288553842108801,0.00645977489525972,0.00251570428592443,"SRD5A1/SIRT1",2
"GO:0110096","BP","GO:0110096","cellular response to aldehyde","2/173","10/21081",0.00288553842108801,0.00645977489525972,0.00251570428592443,"AKR1B10/AKR1B1",2
"GO:1903862","BP","GO:1903862","positive regulation of oxidative phosphorylation","2/173","10/21081",0.00288553842108801,0.00645977489525972,0.00251570428592443,"CDK1/VCP",2
"GO:1905906","BP","GO:1905906","regulation of amyloid fibril formation","2/173","10/21081",0.00288553842108801,0.00645977489525972,0.00251570428592443,"APP/PSEN1",2
"GO:2000270","BP","GO:2000270","negative regulation of fibroblast apoptotic process","2/173","10/21081",0.00288553842108801,0.00645977489525972,0.00251570428592443,"PIK3CA/PIK3CG",2
"GO:1904427","BP","GO:1904427","positive regulation of calcium ion transmembrane transport","4/173","72/21081",0.00292002037815979,0.00653352637535594,0.00254442617137396,"G6PD/SNCA/F2/ABL1",4
"GO:0002756","BP","GO:0002756","MyD88-independent toll-like receptor signaling pathway","3/173","35/21081",0.00293115376658986,0.00654809272042076,0.0025500989103322,"IKBKB/CHUK/TLR4",3
"GO:0045922","BP","GO:0045922","negative regulation of fatty acid metabolic process","3/173","35/21081",0.00293115376658986,0.00654809272042076,0.0025500989103322,"CNR1/AKT1/SIRT1",3
"GO:0098801","BP","GO:0098801","regulation of renal system process","3/173","35/21081",0.00293115376658986,0.00654809272042076,0.0025500989103322,"DRD2/AGTR1/DRD3",3
"GO:0035690","BP","GO:0035690","cellular response to drug","4/173","73/21081",0.00306980920929584,0.00685424032070311,0.00266932548442241,"NOS2/PDE4A/CHEK2/EGFR",4
"GO:0061387","BP","GO:0061387","regulation of extent of cell growth","5/173","120/21081",0.00313289114009235,0.00699141515454433,0.0027227470545252,"GSK3B/ABL1/MAPT/MAPT/MAPT",5
"GO:0031664","BP","GO:0031664","regulation of lipopolysaccharide-mediated signaling pathway","3/173","36/21081",0.00317851365241348,0.00707094476916485,0.00275371918522678,"PRKCA/MIF/MIF",3
"GO:0033280","BP","GO:0033280","response to vitamin D","3/173","36/21081",0.00317851365241348,0.00707094476916485,0.00275371918522678,"PTGS2/PIM1/TYR",3
"GO:0051482","BP","GO:0051482","positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway","3/173","36/21081",0.00317851365241348,0.00707094476916485,0.00275371918522678,"DRD2/AGTR1/DRD3",3
"GO:0060674","BP","GO:0060674","placenta blood vessel development","3/173","36/21081",0.00317851365241348,0.00707094476916485,0.00275371918522678,"PLG/MAPK1/AKT1",3
"GO:0070670","BP","GO:0070670","response to interleukin-4","3/173","36/21081",0.00317851365241348,0.00707094476916485,0.00275371918522678,"CDK4/STAT5B/FASN",3
"GO:0098664","BP","GO:0098664","G protein-coupled serotonin receptor signaling pathway","3/173","36/21081",0.00317851365241348,0.00707094476916485,0.00275371918522678,"HTR1A/HTR2A/HTR4",3
"GO:0014823","BP","GO:0014823","response to activity","4/173","74/21081",0.00322476093516844,0.00716632281042401,0.00279086335063025,"SRD5A1/IL6/MTOR/CDK1",4
"GO:0098586","BP","GO:0098586","cellular response to virus","4/173","74/21081",0.00322476093516844,0.00716632281042401,0.00279086335063025,"IL6/CHUK/MAPK14/MMP12",4
"GO:0000086","BP","GO:0000086","G2/M transition of mitotic cell cycle","8/173","298/21081",0.00329001579217701,0.00730751547358083,0.00284584963012203,"CDK2/CHEK2/CDK4/WEE1/CCNA2/CCND1/CDK1/APP",8
"GO:0031214","BP","GO:0031214","biomineral tissue development","6/173","176/21081",0.00336653213394159,0.00746965798282914,0.00290899464864981,"PPARA/ALOX5/ALOX5/PTGS2/NOS3/MMP13",6
"GO:0110148","BP","GO:0110148","biomineralization","6/173","176/21081",0.00336653213394159,0.00746965798282914,0.00290899464864981,"PPARA/ALOX5/ALOX5/PTGS2/NOS3/MMP13",6
"GO:0007004","BP","GO:0007004","telomere maintenance via telomerase","4/173","75/21081",0.00338496066786403,0.00750271146466055,0.00292186704548349,"MAPK3/TERT/SRC/MAPK1",4
"GO:0008088","BP","GO:0008088","axo-dendritic transport","4/173","75/21081",0.00338496066786403,0.00750271146466055,0.00292186704548349,"APP/MAPT/MAPT/MAPT",4
"GO:0046676","BP","GO:0046676","negative regulation of insulin secretion","3/173","37/21081",0.00343830842579328,0.00761301328879398,0.00296482315095419,"HMGCR/PTPN11/DRD2",3
"GO:0090218","BP","GO:0090218","positive regulation of lipid kinase activity","3/173","37/21081",0.00343830842579328,0.00761301328879398,0.00296482315095419,"SRC/PTK2/F2",3
"GO:0010727","BP","GO:0010727","negative regulation of hydrogen peroxide metabolic process","2/173","11/21081",0.00350779436756778,0.00769072150041048,0.00299508595177696,"MMP3/STAT3",2
"GO:0010918","BP","GO:0010918","positive regulation of mitochondrial membrane potential","2/173","11/21081",0.00350779436756778,0.00769072150041048,0.00299508595177696,"AKT1/VCP",2
"GO:0014820","BP","GO:0014820","tonic smooth muscle contraction","2/173","11/21081",0.00350779436756778,0.00769072150041048,0.00299508595177696,"HTR2A/CD38",2
"GO:0032782","BP","GO:0032782","bile acid secretion","2/173","11/21081",0.00350779436756778,0.00769072150041048,0.00299508595177696,"CES1/CES1",2
"GO:0033197","BP","GO:0033197","response to vitamin E","2/173","11/21081",0.00350779436756778,0.00769072150041048,0.00299508595177696,"PPARG/CCND1",2
"GO:0033210","BP","GO:0033210","leptin-mediated signaling pathway","2/173","11/21081",0.00350779436756778,0.00769072150041048,0.00299508595177696,"SIRT1/STAT3",2
"GO:0034969","BP","GO:0034969","histone arginine methylation","2/173","11/21081",0.00350779436756778,0.00769072150041048,0.00299508595177696,"NR1H4/PRMT1",2
"GO:0042789","BP","GO:0042789","mRNA transcription by RNA polymerase II","2/173","11/21081",0.00350779436756778,0.00769072150041048,0.00299508595177696,"STAT3/C5AR1",2
"GO:0045348","BP","GO:0045348","positive regulation of MHC class II biosynthetic process","2/173","11/21081",0.00350779436756778,0.00769072150041048,0.00299508595177696,"TLR4/SIRT1",2
"GO:0051006","BP","GO:0051006","positive regulation of lipoprotein lipase activity","2/173","11/21081",0.00350779436756778,0.00769072150041048,0.00299508595177696,"NR1H3/NR1H2",2
"GO:0051610","BP","GO:0051610","serotonin uptake","2/173","11/21081",0.00350779436756778,0.00769072150041048,0.00299508595177696,"NOS1/SNCA",2
"GO:0061307","BP","GO:0061307","cardiac neural crest cell differentiation involved in heart development","2/173","11/21081",0.00350779436756778,0.00769072150041048,0.00299508595177696,"MAPK3/MAPK1",2
"GO:0061308","BP","GO:0061308","cardiac neural crest cell development involved in heart development","2/173","11/21081",0.00350779436756778,0.00769072150041048,0.00299508595177696,"MAPK3/MAPK1",2
"GO:0090237","BP","GO:0090237","regulation of arachidonic acid secretion","2/173","11/21081",0.00350779436756778,0.00769072150041048,0.00299508595177696,"MIF/MIF",2
"GO:0140052","BP","GO:0140052","cellular response to oxidised low-density lipoprotein particle stimulus","2/173","11/21081",0.00350779436756778,0.00769072150041048,0.00299508595177696,"AKT1/TLR4",2
"GO:0150104","BP","GO:0150104","transport across blood-brain barrier","2/173","11/21081",0.00350779436756778,0.00769072150041048,0.00299508595177696,"FABP5/ABCG2",2
"GO:1902033","BP","GO:1902033","regulation of hematopoietic stem cell proliferation","2/173","11/21081",0.00350779436756778,0.00769072150041048,0.00299508595177696,"PIM1/ACE",2
"GO:1903800","BP","GO:1903800","positive regulation of production of miRNAs involved in gene silencing by miRNA","2/173","11/21081",0.00350779436756778,0.00769072150041048,0.00299508595177696,"IL6/EGFR",2
"GO:1904526","BP","GO:1904526","regulation of microtubule binding","2/173","11/21081",0.00350779436756778,0.00769072150041048,0.00299508595177696,"ABL1/PPP2CA",2
"GO:2000278","BP","GO:2000278","regulation of DNA biosynthetic process","5/173","124/21081",0.00360573809262298,0.00790138275170451,0.00307712618094152,"MAPK3/PPARG/SRC/MAPK1/NOX4",5
"GO:0060070","BP","GO:0060070","canonical Wnt signaling pathway","9/173","372/21081",0.00370646599919246,0.00811054100254353,0.00315858107938671,"XIAP/SRC/GSK3B/LRRK2/EGFR/PPP1CA/MAPK14/VCP/PSEN1",9
"GO:0034368","BP","GO:0034368","protein-lipid complex remodeling","3/173","38/21081",0.00371072998563065,0.00811054100254353,0.00315858107938671,"AGTR1/MPO/CETP",3
"GO:0034369","BP","GO:0034369","plasma lipoprotein particle remodeling","3/173","38/21081",0.00371072998563065,0.00811054100254353,0.00315858107938671,"AGTR1/MPO/CETP",3
"GO:0043368","BP","GO:0043368","positive T cell selection","3/173","38/21081",0.00371072998563065,0.00811054100254353,0.00315858107938671,"IL6/MTOR/STAT3",3
"GO:0045730","BP","GO:0045730","respiratory burst","3/173","38/21081",0.00371072998563065,0.00811054100254353,0.00315858107938671,"PIK3CG/INSR/MPO",3
"GO:0006278","BP","GO:0006278","RNA-dependent DNA biosynthetic process","4/173","77/21081",0.00372144112621862,0.00812977035748222,0.00316606978780445,"MAPK3/TERT/SRC/MAPK1",4
"GO:0009062","BP","GO:0009062","fatty acid catabolic process","5/173","125/21081",0.00373152820485602,0.00814761733937987,0.00317302014282126,"PPARA/FABP1/CNR1/MTOR/AKT1",5
"GO:2000241","BP","GO:2000241","regulation of reproductive process","6/173","180/21081",0.00375826439969688,0.00820177988408426,0.00319411328430973,"ESR1/CNR1/TACR1/SRC/HDAC4/INSR",6
"GO:0033146","BP","GO:0033146","regulation of intracellular estrogen receptor signaling pathway","3/173","39/21081",0.00399596299832746,0.00870710091276583,0.00339090625283172,"ESR1/SRC/PARP1",3
"GO:0034367","BP","GO:0034367","protein-containing complex remodeling","3/173","39/21081",0.00399596299832746,0.00870710091276583,0.00339090625283172,"AGTR1/MPO/CETP",3
"GO:0036314","BP","GO:0036314","response to sterol","3/173","39/21081",0.00399596299832746,0.00870710091276583,0.00339090625283172,"CES1/CES1/RORA",3
"GO:0060485","BP","GO:0060485","mesenchyme development","8/173","308/21081",0.00401296355808124,0.00873966281818924,0.00340358720942227,"MAPK3/MDM2/IL6/GSK3B/MTOR/MAPK1/NOS3/PPP2CA",8
"GO:0021536","BP","GO:0021536","diencephalon development","4/173","79/21081",0.00407991726648012,0.00887637914248542,0.00345683021688994,"SRD5A1/SLC6A3/SLC6A3/DRD2",4
"GO:1905207","BP","GO:1905207","regulation of cardiocyte differentiation","4/173","79/21081",0.00407991726648012,0.00887637914248542,0.00345683021688994,"G6PD/PPARA/MTOR/EGFR",4
"GO:0051149","BP","GO:0051149","positive regulation of muscle cell differentiation","5/173","128/21081",0.00412776801858371,0.00897588859312293,0.00349558332446997,"MDM2/MTOR/SIRT1/ABL1/MAPK14",5
"GO:0018393","BP","GO:0018393","internal peptidyl-lysine acetylation","6/173","184/21081",0.00418287243458178,0.00901184226859101,0.00350958517700142,"MAPK3/NOS1/SNCA/SIRT1/OGT/EP300",6
"GO:0000012","BP","GO:0000012","single strand break repair","2/173","12/21081",0.00418672079035035,0.00901184226859101,0.00350958517700142,"PARP1/SIRT1",2
"GO:0006853","BP","GO:0006853","carnitine shuttle","2/173","12/21081",0.00418672079035035,0.00901184226859101,0.00350958517700142,"ACACA/ACACA",2
"GO:0006857","BP","GO:0006857","oligopeptide transport","2/173","12/21081",0.00418672079035035,0.00901184226859101,0.00350958517700142,"ABCC1/ABCC1",2
"GO:0010232","BP","GO:0010232","vascular transport","2/173","12/21081",0.00418672079035035,0.00901184226859101,0.00350958517700142,"FABP5/ABCG2",2
"GO:0014745","BP","GO:0014745","negative regulation of muscle adaptation","2/173","12/21081",0.00418672079035035,0.00901184226859101,0.00350958517700142,"MTOR/NOS3",2
"GO:0031987","BP","GO:0031987","locomotion involved in locomotory behavior","2/173","12/21081",0.00418672079035035,0.00901184226859101,0.00350958517700142,"DRD2/DRD3",2
"GO:0032308","BP","GO:0032308","positive regulation of prostaglandin secretion","2/173","12/21081",0.00418672079035035,0.00901184226859101,0.00350958517700142,"MIF/MIF",2
"GO:0032494","BP","GO:0032494","response to peptidoglycan","2/173","12/21081",0.00418672079035035,0.00901184226859101,0.00350958517700142,"IL6/C5AR1",2
"GO:0034776","BP","GO:0034776","response to histamine","2/173","12/21081",0.00418672079035035,0.00901184226859101,0.00350958517700142,"DRD2/DRD3",2
"GO:0038110","BP","GO:0038110","interleukin-2-mediated signaling pathway","2/173","12/21081",0.00418672079035035,0.00901184226859101,0.00350958517700142,"STAT5B/IL2",2
"GO:0046322","BP","GO:0046322","negative regulation of fatty acid oxidation","2/173","12/21081",0.00418672079035035,0.00901184226859101,0.00350958517700142,"CNR1/AKT1",2
"GO:0060439","BP","GO:0060439","trachea morphogenesis","2/173","12/21081",0.00418672079035035,0.00901184226859101,0.00350958517700142,"MAPK3/MAPK1",2
"GO:0061365","BP","GO:0061365","positive regulation of triglyceride lipase activity","2/173","12/21081",0.00418672079035035,0.00901184226859101,0.00350958517700142,"NR1H3/NR1H2",2
"GO:0071073","BP","GO:0071073","positive regulation of phospholipid biosynthetic process","2/173","12/21081",0.00418672079035035,0.00901184226859101,0.00350958517700142,"NR1H4/HTR2A",2
"GO:0072540","BP","GO:0072540","T-helper 17 cell lineage commitment","2/173","12/21081",0.00418672079035035,0.00901184226859101,0.00350958517700142,"IL6/STAT3",2
"GO:0090205","BP","GO:0090205","positive regulation of cholesterol metabolic process","2/173","12/21081",0.00418672079035035,0.00901184226859101,0.00350958517700142,"CES1/CES1",2
"GO:0097284","BP","GO:0097284","hepatocyte apoptotic process","2/173","12/21081",0.00418672079035035,0.00901184226859101,0.00350958517700142,"BCL2L1/PIK3CG",2
"GO:0150065","BP","GO:0150065","regulation of deacetylase activity","2/173","12/21081",0.00418672079035035,0.00901184226859101,0.00350958517700142,"MAPK8/LRRK2",2
"GO:1903961","BP","GO:1903961","positive regulation of anion transmembrane transport","2/173","12/21081",0.00418672079035035,0.00901184226859101,0.00350958517700142,"CFTR/PSEN1",2
"GO:0002065","BP","GO:0002065","columnar/cuboidal epithelial cell differentiation","5/173","129/21081",0.00426627926081386,0.00917665468115071,0.00357376996662222,"SERPINE1/SRC/GSK3B/ABL1/FASN",5
"GO:0032653","BP","GO:0032653","regulation of interleukin-10 production","4/173","80/21081",0.00426760876675778,0.00917665468115071,0.00357376996662222,"IDO1/IL6/TLR4/STAT3",4
"GO:0006084","BP","GO:0006084","acetyl-CoA metabolic process","3/173","40/21081",0.00429418502814081,0.00918766098161065,0.00357805627654605,"FASN/ACACA/ACACA",3
"GO:0032660","BP","GO:0032660","regulation of interleukin-17 production","3/173","40/21081",0.00429418502814081,0.00918766098161065,0.00357805627654605,"IL6/TLR4/IL2",3
"GO:0043029","BP","GO:0043029","T cell homeostasis","3/173","40/21081",0.00429418502814081,0.00918766098161065,0.00357805627654605,"AKT1/STAT5B/IL2",3
"GO:0044319","BP","GO:0044319","wound healing, spreading of cells","3/173","40/21081",0.00429418502814081,0.00918766098161065,0.00357805627654605,"MTOR/RHOA/MMP12",3
"GO:0048384","BP","GO:0048384","retinoic acid receptor signaling pathway","3/173","40/21081",0.00429418502814081,0.00918766098161065,0.00357805627654605,"PPARG/NR1H2/CYP26A1",3
"GO:0051281","BP","GO:0051281","positive regulation of release of sequestered calcium ion into cytosol","3/173","40/21081",0.00429418502814081,0.00918766098161065,0.00357805627654605,"SNCA/F2/ABL1",3
"GO:0060323","BP","GO:0060323","head morphogenesis","3/173","40/21081",0.00429418502814081,0.00918766098161065,0.00357805627654605,"PTPN11/MMP2/EP300",3
"GO:0071312","BP","GO:0071312","cellular response to alkaloid","3/173","40/21081",0.00429418502814081,0.00918766098161065,0.00357805627654605,"BCL2L1/MDM2/CCNA2",3
"GO:0090505","BP","GO:0090505","epiboly involved in wound healing","3/173","40/21081",0.00429418502814081,0.00918766098161065,0.00357805627654605,"MTOR/RHOA/MMP12",3
"GO:0016482","BP","GO:0016482","cytosolic transport","6/173","185/21081",0.00429435036702253,0.00918766098161065,0.00357805627654605,"MAPK3/CES1/CES1/SRC/MAPK1/LRRK2",6
"GO:0006402","BP","GO:0006402","mRNA catabolic process","10/173","454/21081",0.00438800162018251,0.00938330089791418,0.00365424657480301,"PRKCA/MTOR/AKT1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/MAPK14/PPP2CA",10
"GO:0006941","BP","GO:0006941","striated muscle contraction","6/173","186/21081",0.00440800923352263,0.00942134367869098,0.00366906201159461,"MTOR/PIK3CA/PIK3CG/CHUK/NOS1/HDAC4",6
"GO:0016575","BP","GO:0016575","histone deacetylation","4/173","81/21081",0.00446104367845508,0.00951554949284921,0.00370574966314277,"MAPK8/LRRK2/HDAC4/SIRT1",4
"GO:0031016","BP","GO:0031016","pancreas development","4/173","81/21081",0.00446104367845508,0.00951554949284921,0.00370574966314277,"IL6/GSK3B/AKT1/INSR",4
"GO:0072678","BP","GO:0072678","T cell migration","4/173","81/21081",0.00446104367845508,0.00951554949284921,0.00370574966314277,"CXCR3/PIK3CG/RHOA/APP",4
"GO:2000573","BP","GO:2000573","positive regulation of DNA biosynthetic process","4/173","81/21081",0.00446104367845508,0.00951554949284921,0.00370574966314277,"MAPK3/SRC/MAPK1/NOX4",4
"GO:1901657","BP","GO:1901657","glycosyl compound metabolic process","5/173","131/21081",0.0045532025045239,0.00970725411024688,0.00378040739277554,"AKR1B10/LRRK2/AKR1B1/AKR1C1/RHOA",5
"GO:0007210","BP","GO:0007210","serotonin receptor signaling pathway","3/173","41/21081",0.00460556666570728,0.00977963656301362,0.00380859612219777,"HTR1A/HTR2A/HTR4",3
"GO:0042759","BP","GO:0042759","long-chain fatty acid biosynthetic process","3/173","41/21081",0.00460556666570728,0.00977963656301362,0.00380859612219777,"ALOX5/ALOX5/PTGS2",3
"GO:0045022","BP","GO:0045022","early endosome to late endosome transport","3/173","41/21081",0.00460556666570728,0.00977963656301362,0.00380859612219777,"MAPK3/SRC/MAPK1",3
"GO:0045740","BP","GO:0045740","positive regulation of DNA replication","3/173","41/21081",0.00460556666570728,0.00977963656301362,0.00380859612219777,"CDK2/EGFR/CDK1",3
"GO:0050892","BP","GO:0050892","intestinal absorption","3/173","41/21081",0.00460556666570728,0.00977963656301362,0.00380859612219777,"NPC1L1/FABP1/AKR1C1",3
"GO:0051354","BP","GO:0051354","negative regulation of oxidoreductase activity","3/173","41/21081",0.00460556666570728,0.00977963656301362,0.00380859612219777,"CNR1/LRRK2/SNCA",3
"GO:0051930","BP","GO:0051930","regulation of sensory perception of pain","3/173","41/21081",0.00460556666570728,0.00977963656301362,0.00380859612219777,"FABP5/MTOR/MGLL",3
"GO:0090504","BP","GO:0090504","epiboly","3/173","41/21081",0.00460556666570728,0.00977963656301362,0.00380859612219777,"MTOR/RHOA/MMP12",3
"GO:0009152","BP","GO:0009152","purine ribonucleotide biosynthetic process","6/173","188/21081",0.00464197106073241,0.00985201550302297,0.00383678348360657,"PARP1/STAT3/FASN/ACACA/ACACA/VCP",6
"GO:1903311","BP","GO:1903311","regulation of mRNA metabolic process","9/173","386/21081",0.00470891992610515,0.00998911670794846,0.00389017637955556,"PRKCA/MTOR/AKT1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/MAPK14",9
"GO:0044839","BP","GO:0044839","cell cycle G2/M phase transition","8/173","317/21081",0.00476338337827303,0.0100996087696019,0.0039332065714073,"CDK2/CHEK2/CDK4/WEE1/CCNA2/CCND1/CDK1/APP",8
"GO:0048675","BP","GO:0048675","axon extension","5/173","133/21081",0.00485360747673955,0.0102806471429045,0.00400371042316974,"GSK3B/ABL1/MAPT/MAPT/MAPT",5
"GO:0072089","BP","GO:0072089","stem cell proliferation","5/173","133/21081",0.00485360747673955,0.0102806471429045,0.00400371042316974,"TERT/DRD2/PIM1/LRRK2/ACE",5
"GO:0032613","BP","GO:0032613","interleukin-10 production","4/173","83/21081",0.00486546222194324,0.0102954925204367,0.00400949182894463,"IDO1/IL6/TLR4/STAT3",4
"GO:0051279","BP","GO:0051279","regulation of release of sequestered calcium ion into cytosol","4/173","83/21081",0.00486546222194324,0.0102954925204367,0.00400949182894463,"NOS1/SNCA/F2/ABL1",4
"GO:0002679","BP","GO:0002679","respiratory burst involved in defense response","2/173","13/21081",0.00492135656544311,0.010324654638281,0.00402084876723384,"PIK3CG/MPO",2
"GO:0003084","BP","GO:0003084","positive regulation of systemic arterial blood pressure","2/173","13/21081",0.00492135656544311,0.010324654638281,0.00402084876723384,"ACE/RHOA",2
"GO:0030157","BP","GO:0030157","pancreatic juice secretion","2/173","13/21081",0.00492135656544311,0.010324654638281,0.00402084876723384,"NR1H3/NR1H2",2
"GO:0031053","BP","GO:0031053","primary miRNA processing","2/173","13/21081",0.00492135656544311,0.010324654638281,0.00402084876723384,"IL6/STAT3",2
"GO:0032306","BP","GO:0032306","regulation of prostaglandin secretion","2/173","13/21081",0.00492135656544311,0.010324654638281,0.00402084876723384,"MIF/MIF",2
"GO:0032429","BP","GO:0032429","regulation of phospholipase A2 activity","2/173","13/21081",0.00492135656544311,0.010324654638281,0.00402084876723384,"AGTR1/EGFR",2
"GO:0035723","BP","GO:0035723","interleukin-15-mediated signaling pathway","2/173","13/21081",0.00492135656544311,0.010324654638281,0.00402084876723384,"STAT5B/STAT3",2
"GO:0051481","BP","GO:0051481","negative regulation of cytosolic calcium ion concentration","2/173","13/21081",0.00492135656544311,0.010324654638281,0.00402084876723384,"DRD2/DRD3",2
"GO:0051549","BP","GO:0051549","positive regulation of keratinocyte migration","2/173","13/21081",0.00492135656544311,0.010324654638281,0.00402084876723384,"MTOR/MMP9",2
"GO:0051974","BP","GO:0051974","negative regulation of telomerase activity","2/173","13/21081",0.00492135656544311,0.010324654638281,0.00402084876723384,"PPARG/SRC",2
"GO:0060019","BP","GO:0060019","radial glial cell differentiation","2/173","13/21081",0.00492135656544311,0.010324654638281,0.00402084876723384,"RHOA/STAT3",2
"GO:0060123","BP","GO:0060123","regulation of growth hormone secretion","2/173","13/21081",0.00492135656544311,0.010324654638281,0.00402084876723384,"PTPN11/DRD2",2
"GO:0060736","BP","GO:0060736","prostate gland growth","2/173","13/21081",0.00492135656544311,0.010324654638281,0.00402084876723384,"CYP19A1/ESR1",2
"GO:0070106","BP","GO:0070106","interleukin-27-mediated signaling pathway","2/173","13/21081",0.00492135656544311,0.010324654638281,0.00402084876723384,"STAT3/TYK2",2
"GO:0071350","BP","GO:0071350","cellular response to interleukin-15","2/173","13/21081",0.00492135656544311,0.010324654638281,0.00402084876723384,"STAT5B/STAT3",2
"GO:0071352","BP","GO:0071352","cellular response to interleukin-2","2/173","13/21081",0.00492135656544311,0.010324654638281,0.00402084876723384,"STAT5B/IL2",2
"GO:2000194","BP","GO:2000194","regulation of female gonad development","2/173","13/21081",0.00492135656544311,0.010324654638281,0.00402084876723384,"SRC/INSR",2
"GO:0002209","BP","GO:0002209","behavioral defense response","3/173","42/21081",0.00493027165475928,0.010324654638281,0.00402084876723384,"HTR1A/DPP4/EP300",3
"GO:0032733","BP","GO:0032733","positive regulation of interleukin-10 production","3/173","42/21081",0.00493027165475928,0.010324654638281,0.00402084876723384,"IL6/TLR4/STAT3",3
"GO:0051931","BP","GO:0051931","regulation of sensory perception","3/173","42/21081",0.00493027165475928,0.010324654638281,0.00402084876723384,"FABP5/MTOR/MGLL",3
"GO:1902622","BP","GO:1902622","regulation of neutrophil migration","3/173","42/21081",0.00493027165475928,0.010324654638281,0.00402084876723384,"CXCL8/DPP4/C5AR1",3
"GO:0006814","BP","GO:0006814","sodium ion transport","7/173","253/21081",0.00498519585430581,0.010434530632978,0.00406363903705924,"SLC6A3/SLC6A3/DRD2/DRD3/NOS3/AKT1/NOS1",7
"GO:0010822","BP","GO:0010822","positive regulation of mitochondrion organization","5/173","134/21081",0.00500897046342232,0.0104739741629338,0.00407899998368208,"SREBF2/MAPK8/GSK3B/CSNK2A2/MMP9",5
"GO:0031623","BP","GO:0031623","receptor internalization","5/173","134/21081",0.00500897046342232,0.0104739741629338,0.00407899998368208,"DRD2/DRD3/INSR/SNCA/CXCL8",5
"GO:0002312","BP","GO:0002312","B cell activation involved in immune response","4/173","84/21081",0.00507660299698115,0.0106101751766714,0.00413204230784392,"IL6/TLR4/ABL1/IL2",4
"GO:0018394","BP","GO:0018394","peptidyl-lysine acetylation","6/173","192/21081",0.00513718082815282,0.0107315050829997,0.00417929320594951,"MAPK3/NOS1/SNCA/SIRT1/OGT/EP300",6
"GO:0032467","BP","GO:0032467","positive regulation of cytokinesis","3/173","43/21081",0.00526845701705561,0.0109787512827216,0.00427558113152031,"DRD2/DRD3/RHOA",3
"GO:0032892","BP","GO:0032892","positive regulation of organic acid transport","3/173","43/21081",0.00526845701705561,0.0109787512827216,0.00427558113152031,"MIF/MIF/PSEN1",3
"GO:0043267","BP","GO:0043267","negative regulation of potassium ion transport","3/173","43/21081",0.00526845701705561,0.0109787512827216,0.00427558113152031,"HTR2A/NOS3/NOS1",3
"GO:0048713","BP","GO:0048713","regulation of oligodendrocyte differentiation","3/173","43/21081",0.00526845701705561,0.0109787512827216,0.00427558113152031,"PPARG/DRD3/MTOR",3
"GO:0090278","BP","GO:0090278","negative regulation of peptide hormone secretion","3/173","43/21081",0.00526845701705561,0.0109787512827216,0.00427558113152031,"HMGCR/PTPN11/DRD2",3
"GO:0060998","BP","GO:0060998","regulation of dendritic spine development","4/173","85/21081",0.00529380143582287,0.0110261579905938,0.00429404326992443,"MTOR/LRRK2/IL2/PSEN1",4
"GO:0007160","BP","GO:0007160","cell-matrix adhesion","7/173","257/21081",0.00542241413007482,0.0112829763166934,0.00439405897854405,"SERPINE1/SRC/GSK3B/PTK2/RHOA/ABL1/MMP12",7
"GO:0060560","BP","GO:0060560","developmental growth involved in morphogenesis","7/173","257/21081",0.00542241413007482,0.0112829763166934,0.00439405897854405,"ESR1/GSK3B/ABL1/APP/MAPT/MAPT/MAPT",7
"GO:0009064","BP","GO:0009064","glutamine family amino acid metabolic process","4/173","86/21081",0.00551713393486408,0.0114744503618392,0.00446862691377816,"NR1H4/NOS2/NOS3/NOS1",4
"GO:0034142","BP","GO:0034142","toll-like receptor 4 signaling pathway","3/173","44/21081",0.00562027317554837,0.0116547294889727,0.00453883508358996,"NR1H4/NR1H3/TLR4",3
"GO:0046621","BP","GO:0046621","negative regulation of organ growth","3/173","44/21081",0.00562027317554837,0.0116547294889727,0.00453883508358996,"G6PD/PPARA/PTK2",3
"GO:0046825","BP","GO:0046825","regulation of protein export from nucleus","3/173","44/21081",0.00562027317554837,0.0116547294889727,0.00453883508358996,"PTPN11/MDM2/GSK3B",3
"GO:0071470","BP","GO:0071470","cellular response to osmotic stress","3/173","44/21081",0.00562027317554837,0.0116547294889727,0.00453883508358996,"PTGS2/AKR1B1/MAPK10",3
"GO:0090207","BP","GO:0090207","regulation of triglyceride metabolic process","3/173","44/21081",0.00562027317554837,0.0116547294889727,0.00453883508358996,"NR1H3/NR1H2/PIK3CG",3
"GO:0098927","BP","GO:0098927","vesicle-mediated transport between endosomal compartments","3/173","44/21081",0.00562027317554837,0.0116547294889727,0.00453883508358996,"MAPK3/SRC/MAPK1",3
"GO:0051153","BP","GO:0051153","regulation of striated muscle cell differentiation","5/173","138/21081",0.00566579771994626,0.0117278814948995,0.00456732350893265,"G6PD/PPARA/MTOR/HDAC4/MAPK14",5
"GO:0031345","BP","GO:0031345","negative regulation of cell projection organization","6/173","196/21081",0.00567012460181079,0.0117278814948995,0.00456732350893265,"MDM2/LRRK2/PTK2/RHOA/CD38/PSEN1",6
"GO:0014854","BP","GO:0014854","response to inactivity","2/173","14/21081",0.00571075236830952,0.0117278814948995,0.00456732350893265,"DRD2/HDAC4",2
"GO:0035641","BP","GO:0035641","locomotory exploration behavior","2/173","14/21081",0.00571075236830952,0.0117278814948995,0.00456732350893265,"LRRK2/DPP4",2
"GO:0035791","BP","GO:0035791","platelet-derived growth factor receptor-beta signaling pathway","2/173","14/21081",0.00571075236830952,0.0117278814948995,0.00456732350893265,"SRC/ABL1",2
"GO:0035815","BP","GO:0035815","positive regulation of renal sodium excretion","2/173","14/21081",0.00571075236830952,0.0117278814948995,0.00456732350893265,"DRD2/DRD3",2
"GO:0036092","BP","GO:0036092","phosphatidylinositol-3-phosphate biosynthetic process","2/173","14/21081",0.00571075236830952,0.0117278814948995,0.00456732350893265,"PIK3CA/PIK3CG",2
"GO:0038166","BP","GO:0038166","angiotensin-activated signaling pathway","2/173","14/21081",0.00571075236830952,0.0117278814948995,0.00456732350893265,"AGTR1/SRC",2
"GO:0042135","BP","GO:0042135","neurotransmitter catabolic process","2/173","14/21081",0.00571075236830952,0.0117278814948995,0.00456732350893265,"MAOA/MAOB",2
"GO:0050966","BP","GO:0050966","detection of mechanical stimulus involved in sensory perception of pain","2/173","14/21081",0.00571075236830952,0.0117278814948995,0.00456732350893265,"BACE1/HTR2A",2
"GO:0051589","BP","GO:0051589","negative regulation of neurotransmitter transport","2/173","14/21081",0.00571075236830952,0.0117278814948995,0.00456732350893265,"NOS1/SNCA",2
"GO:0060397","BP","GO:0060397","growth hormone receptor signaling pathway via JAK-STAT","2/173","14/21081",0.00571075236830952,0.0117278814948995,0.00456732350893265,"STAT5B/STAT3",2
"GO:0061052","BP","GO:0061052","negative regulation of cell growth involved in cardiac muscle cell development","2/173","14/21081",0.00571075236830952,0.0117278814948995,0.00456732350893265,"G6PD/PPARA",2
"GO:0070669","BP","GO:0070669","response to interleukin-2","2/173","14/21081",0.00571075236830952,0.0117278814948995,0.00456732350893265,"STAT5B/IL2",2
"GO:0070672","BP","GO:0070672","response to interleukin-15","2/173","14/21081",0.00571075236830952,0.0117278814948995,0.00456732350893265,"STAT5B/STAT3",2
"GO:0070914","BP","GO:0070914","UV-damage excision repair","2/173","14/21081",0.00571075236830952,0.0117278814948995,0.00456732350893265,"MC1R/SIRT1",2
"GO:0099550","BP","GO:0099550","trans-synaptic signaling, modulating synaptic transmission","2/173","14/21081",0.00571075236830952,0.0117278814948995,0.00456732350893265,"PLG/CNR1",2
"GO:0106014","BP","GO:0106014","regulation of inflammatory response to wounding","2/173","14/21081",0.00571075236830952,0.0117278814948995,0.00456732350893265,"ALOX5/ALOX5",2
"GO:1901160","BP","GO:1901160","primary amino compound metabolic process","2/173","14/21081",0.00571075236830952,0.0117278814948995,0.00456732350893265,"SRD5A1/HTR1A",2
"GO:1903236","BP","GO:1903236","regulation of leukocyte tethering or rolling","2/173","14/21081",0.00571075236830952,0.0117278814948995,0.00456732350893265,"ELANE/ELANE",2
"GO:0003007","BP","GO:0003007","heart morphogenesis","7/173","261/21081",0.00588781887754062,0.0120856726621595,0.00470666223010112,"MDM2/MTOR/NOS3/PIM1/INSR/PTK2/PSEN1",7
"GO:0045666","BP","GO:0045666","positive regulation of neuron differentiation","9/173","400/21081",0.00591114123186851,0.0121276866703087,0.00472302422755206,"CNR1/MTOR/RHOA/MAPT/MAPT/MAPT/IL2/EP300/PSEN1",9
"GO:1903051","BP","GO:1903051","negative regulation of proteolysis involved in cellular protein catabolic process","4/173","88/21081",0.00598250219223566,0.0122396229346041,0.00476661685181593,"CSNK2A1/CSNK2A2/OGT/PSEN1",4
"GO:2000243","BP","GO:2000243","positive regulation of reproductive process","4/173","88/21081",0.00598250219223566,0.0122396229346041,0.00476661685181593,"TACR1/SRC/HDAC4/INSR",4
"GO:0021587","BP","GO:0021587","cerebellum morphogenesis","3/173","45/21081",0.00598586407580777,0.0122396229346041,0.00476661685181593,"PTPN11/RORA/ABL1",3
"GO:0032965","BP","GO:0032965","regulation of collagen biosynthetic process","3/173","45/21081",0.00598586407580777,0.0122396229346041,0.00476661685181593,"PPARG/IL6/F2",3
"GO:0046949","BP","GO:0046949","fatty-acyl-CoA biosynthetic process","3/173","45/21081",0.00598586407580777,0.0122396229346041,0.00476661685181593,"FASN/ACACA/ACACA",3
"GO:0051154","BP","GO:0051154","negative regulation of striated muscle cell differentiation","3/173","45/21081",0.00598586407580777,0.0122396229346041,0.00476661685181593,"G6PD/PPARA/HDAC4",3
"GO:0051180","BP","GO:0051180","vitamin transport","3/173","45/21081",0.00598586407580777,0.0122396229346041,0.00476661685181593,"ABCC1/ABCC1/ABCG2",3
"GO:0032680","BP","GO:0032680","regulation of tumor necrosis factor production","5/173","141/21081",0.00619671845534035,0.0126585849599717,0.00492977804240639,"PTPN11/TLR4/MIF/MIF/MC1R",5
"GO:0045824","BP","GO:0045824","negative regulation of innate immune response","5/173","141/21081",0.00619671845534035,0.0126585849599717,0.00492977804240639,"NR1H3/DRD2/PPARG/NR1H2/MMP12",5
"GO:0048041","BP","GO:0048041","focal adhesion assembly","4/173","89/21081",0.006224686192909,0.0127096067437147,0.00494964804130249,"SRC/PTK2/RHOA/ABL1",4
"GO:0021543","BP","GO:0021543","pallium development","6/173","200/21081",0.00624242417534017,0.0127397023636025,0.00496136852400765,"SRD5A1/GSK3B/CSNK2A2/EGFR/RHOA/PSEN1",6
"GO:0001953","BP","GO:0001953","negative regulation of cell-matrix adhesion","3/173","46/21081",0.00636536730572656,0.0129781409222803,0.00505422638882824,"SERPINE1/SRC/MMP12",3
"GO:0031018","BP","GO:0031018","endocrine pancreas development","3/173","46/21081",0.00636536730572656,0.0129781409222803,0.00505422638882824,"IL6/GSK3B/AKT1",3
"GO:0030183","BP","GO:0030183","B cell differentiation","5/173","142/21081",0.00638120562350368,0.0129979591055931,0.00506194441143856,"IL6/HDAC4/STAT5B/ABL1/EP300",5
"GO:0055007","BP","GO:0055007","cardiac muscle cell differentiation","5/173","142/21081",0.00638120562350368,0.0129979591055931,0.00506194441143856,"G6PD/PPARA/MTOR/NOX4/CDK1",5
"GO:0009260","BP","GO:0009260","ribonucleotide biosynthetic process","6/173","201/21081",0.00639183809288801,0.013013378081783,0.00506794920032277,"PARP1/STAT3/FASN/ACACA/ACACA/VCP",6
"GO:0061844","BP","GO:0061844","antimicrobial humoral immune response mediated by antimicrobial peptide","4/173","90/21081",0.00647330071089584,0.0131729189274887,0.005130081023154,"F2/CXCL8/ELANE/ELANE",4
"GO:0006000","BP","GO:0006000","fructose metabolic process","2/173","15/21081",0.00655397054677219,0.0132230868248979,0.00514961848329379,"AKR1B1/PFKFB3",2
"GO:0009415","BP","GO:0009415","response to water","2/173","15/21081",0.00655397054677219,0.0132230868248979,0.00514961848329379,"AKR1B1/MAPK10",2
"GO:0010763","BP","GO:0010763","positive regulation of fibroblast migration","2/173","15/21081",0.00655397054677219,0.0132230868248979,0.00514961848329379,"AKT1/PTK2",2
"GO:0010889","BP","GO:0010889","regulation of sequestering of triglyceride","2/173","15/21081",0.00655397054677219,0.0132230868248979,0.00514961848329379,"PPARA/PPARG",2
"GO:0018216","BP","GO:0018216","peptidyl-arginine methylation","2/173","15/21081",0.00655397054677219,0.0132230868248979,0.00514961848329379,"NR1H4/PRMT1",2
"GO:0033604","BP","GO:0033604","negative regulation of catecholamine secretion","2/173","15/21081",0.00655397054677219,0.0132230868248979,0.00514961848329379,"DRD2/CNR1",2
"GO:0035358","BP","GO:0035358","regulation of peroxisome proliferator activated receptor signaling pathway","2/173","15/21081",0.00655397054677219,0.0132230868248979,0.00514961848329379,"FABP5/SIRT1",2
"GO:0035635","BP","GO:0035635","entry of bacterium into host cell","2/173","15/21081",0.00655397054677219,0.0132230868248979,0.00514961848329379,"SRC/CXCL8",2
"GO:0045472","BP","GO:0045472","response to ether","2/173","15/21081",0.00655397054677219,0.0132230868248979,0.00514961848329379,"MDM2/CDK4",2
"GO:0048548","BP","GO:0048548","regulation of pinocytosis","2/173","15/21081",0.00655397054677219,0.0132230868248979,0.00514961848329379,"NR1H3/NR1H2",2
"GO:0051791","BP","GO:0051791","medium-chain fatty acid metabolic process","2/173","15/21081",0.00655397054677219,0.0132230868248979,0.00514961848329379,"CES1/CES1",2
"GO:0070885","BP","GO:0070885","negative regulation of calcineurin-NFAT signaling cascade","2/173","15/21081",0.00655397054677219,0.0132230868248979,0.00514961848329379,"GSK3B/MTOR",2
"GO:0071474","BP","GO:0071474","cellular hyperosmotic response","2/173","15/21081",0.00655397054677219,0.0132230868248979,0.00514961848329379,"AKR1B1/MAPK10",2
"GO:0071501","BP","GO:0071501","cellular response to sterol depletion","2/173","15/21081",0.00655397054677219,0.0132230868248979,0.00514961848329379,"NPC1L1/SREBF2",2
"GO:0099171","BP","GO:0099171","presynaptic modulation of chemical synaptic transmission","2/173","15/21081",0.00655397054677219,0.0132230868248979,0.00514961848329379,"CNR1/PRKCB",2
"GO:0106057","BP","GO:0106057","negative regulation of calcineurin-mediated signaling","2/173","15/21081",0.00655397054677219,0.0132230868248979,0.00514961848329379,"GSK3B/MTOR",2
"GO:0106070","BP","GO:0106070","regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway","2/173","15/21081",0.00655397054677219,0.0132230868248979,0.00514961848329379,"PRKCA/NOS1",2
"GO:2001171","BP","GO:2001171","positive regulation of ATP biosynthetic process","2/173","15/21081",0.00655397054677219,0.0132230868248979,0.00514961848329379,"STAT3/VCP",2
"GO:0008584","BP","GO:0008584","male gonad development","5/173","143/21081",0.00656951714459177,0.0132418777738949,0.0051569364582534,"SRD5A1/ESR1/BCL2L1/CCND1/INSR",5
"GO:0072676","BP","GO:0072676","lymphocyte migration","5/173","143/21081",0.00656951714459177,0.0132418777738949,0.0051569364582534,"CXCR3/PIK3CG/AKT1/RHOA/APP",5
"GO:0050866","BP","GO:0050866","negative regulation of cell activation","7/173","267/21081",0.0066411584436643,0.0133799346738405,0.00521070154148401,"IDO1/NR1H3/CNR1/ERBB2/NOS3/F2/IL2",7
"GO:0001974","BP","GO:0001974","blood vessel remodeling","3/173","47/21081",0.00675891421352499,0.0135841298808154,0.00529022362478893,"MDM2/NOS3/ACE",3
"GO:0021762","BP","GO:0021762","substantia nigra development","3/173","47/21081",0.00675891421352499,0.0135841298808154,0.00529022362478893,"G6PD/RHOA/MAOB",3
"GO:0032570","BP","GO:0032570","response to progesterone","3/173","47/21081",0.00675891421352499,0.0135841298808154,0.00529022362478893,"NR1H3/SRC/CD38",3
"GO:0034105","BP","GO:0034105","positive regulation of tissue remodeling","3/173","47/21081",0.00675891421352499,0.0135841298808154,0.00529022362478893,"PRKCA/EGFR/IL2",3
"GO:0046546","BP","GO:0046546","development of primary male sexual characteristics","5/173","144/21081",0.006761693268516,0.0135841298808154,0.00529022362478893,"SRD5A1/ESR1/BCL2L1/CCND1/INSR",5
"GO:1903555","BP","GO:1903555","regulation of tumor necrosis factor superfamily cytokine production","5/173","144/21081",0.006761693268516,0.0135841298808154,0.00529022362478893,"PTPN11/TLR4/MIF/MIF/MC1R",5
"GO:0001892","BP","GO:0001892","embryonic placenta development","4/173","92/21081",0.00699010738575724,0.0140231191133534,0.00546118424054987,"PLG/MAPK1/AKT1/EGFR",4
"GO:0032481","BP","GO:0032481","positive regulation of type I interferon production","4/173","92/21081",0.00699010738575724,0.0140231191133534,0.00546118424054987,"PTPN11/CHUK/TLR4/EP300",4
"GO:0035418","BP","GO:0035418","protein localization to synapse","4/173","92/21081",0.00699010738575724,0.0140231191133534,0.00546118424054987,"MAPK10/MAPT/MAPT/MAPT",4
"GO:0060048","BP","GO:0060048","cardiac muscle contraction","5/173","146/21081",0.0071577993198077,0.0143501465467982,0.0055885422877375,"MTOR/PIK3CA/PIK3CG/NOS1/HDAC4",5
"GO:0030521","BP","GO:0030521","androgen receptor signaling pathway","3/173","48/21081",0.00716663002407763,0.0143501465467982,0.0055885422877375,"RHOA/SIRT1/EP300",3
"GO:0098751","BP","GO:0098751","bone cell development","3/173","48/21081",0.00716663002407763,0.0143501465467982,0.0055885422877375,"PTPN11/SRC/EP300",3
"GO:0120163","BP","GO:0120163","negative regulation of cold-induced thermogenesis","3/173","48/21081",0.00716663002407763,0.0143501465467982,0.0055885422877375,"NR1H3/NR1H2/TLR4",3
"GO:2001252","BP","GO:2001252","positive regulation of chromosome organization","6/173","206/21081",0.00717820164208731,0.0143665467627079,0.00559492921206894,"MAPK3/MAPK1/NOS1/LRRK2/SIRT1/OGT",6
"GO:0032204","BP","GO:0032204","regulation of telomere maintenance","4/173","93/21081",0.00725844015972844,0.0145202976641648,0.00565480619045153,"MAPK3/SRC/MAPK1/PARP1",4
"GO:0002830","BP","GO:0002830","positive regulation of type 2 immune response","2/173","16/21081",0.00745008499518827,0.0147784365754225,0.00575533618970758,"IDO1/IL6",2
"GO:0006206","BP","GO:0006206","pyrimidine nucleobase metabolic process","2/173","16/21081",0.00745008499518827,0.0147784365754225,0.00575533618970758,"MTOR/MAPK1",2
"GO:0010867","BP","GO:0010867","positive regulation of triglyceride biosynthetic process","2/173","16/21081",0.00745008499518827,0.0147784365754225,0.00575533618970758,"NR1H3/NR1H2",2
"GO:0030252","BP","GO:0030252","growth hormone secretion","2/173","16/21081",0.00745008499518827,0.0147784365754225,0.00575533618970758,"PTPN11/DRD2",2
"GO:0035067","BP","GO:0035067","negative regulation of histone acetylation","2/173","16/21081",0.00745008499518827,0.0147784365754225,0.00575533618970758,"SNCA/SIRT1",2
"GO:0045346","BP","GO:0045346","regulation of MHC class II biosynthetic process","2/173","16/21081",0.00745008499518827,0.0147784365754225,0.00575533618970758,"TLR4/SIRT1",2
"GO:0045725","BP","GO:0045725","positive regulation of glycogen biosynthetic process","2/173","16/21081",0.00745008499518827,0.0147784365754225,0.00575533618970758,"AKT1/INSR",2
"GO:0045838","BP","GO:0045838","positive regulation of membrane potential","2/173","16/21081",0.00745008499518827,0.0147784365754225,0.00575533618970758,"AKT1/VCP",2
"GO:0051444","BP","GO:0051444","negative regulation of ubiquitin-protein transferase activity","2/173","16/21081",0.00745008499518827,0.0147784365754225,0.00575533618970758,"ABL1/PSEN1",2
"GO:0051547","BP","GO:0051547","regulation of keratinocyte migration","2/173","16/21081",0.00745008499518827,0.0147784365754225,0.00575533618970758,"MTOR/MMP9",2
"GO:0051770","BP","GO:0051770","positive regulation of nitric-oxide synthase biosynthetic process","2/173","16/21081",0.00745008499518827,0.0147784365754225,0.00575533618970758,"TLR4/LRRK2",2
"GO:0060850","BP","GO:0060850","regulation of transcription involved in cell fate commitment","2/173","16/21081",0.00745008499518827,0.0147784365754225,0.00575533618970758,"RORA/PPARG",2
"GO:0071391","BP","GO:0071391","cellular response to estrogen stimulus","2/173","16/21081",0.00745008499518827,0.0147784365754225,0.00575533618970758,"ESR1/MDM2",2
"GO:0090647","BP","GO:0090647","modulation of age-related behavioral decline","2/173","16/21081",0.00745008499518827,0.0147784365754225,0.00575533618970758,"APP/PSEN1",2
"GO:1902514","BP","GO:1902514","regulation of calcium ion transmembrane transport via high voltage-gated calcium channel","2/173","16/21081",0.00745008499518827,0.0147784365754225,0.00575533618970758,"G6PD/NOS1",2
"GO:1903358","BP","GO:1903358","regulation of Golgi organization","2/173","16/21081",0.00745008499518827,0.0147784365754225,0.00575533618970758,"MAPK3/MAPK1",2
"GO:1903960","BP","GO:1903960","negative regulation of anion transmembrane transport","2/173","16/21081",0.00745008499518827,0.0147784365754225,0.00575533618970758,"MTOR/AKT1",2
"GO:1905244","BP","GO:1905244","regulation of modification of synaptic structure","2/173","16/21081",0.00745008499518827,0.0147784365754225,0.00575533618970758,"RHOA/ABL1",2
"GO:0042098","BP","GO:0042098","T cell proliferation","7/173","273/21081",0.0074640549728442,0.0147992391878745,0.00576343758985735,"IDO1/IL6/ERBB2/PIK3CG/STAT5B/ABL1/IL2",7
"GO:0050772","BP","GO:0050772","positive regulation of axonogenesis","4/173","94/21081",0.00753348466239742,0.0149229726482642,0.00581162453161023,"RHOA/MAPT/MAPT/MAPT",4
"GO:1903533","BP","GO:1903533","regulation of protein targeting","4/173","94/21081",0.00753348466239742,0.0149229726482642,0.00581162453161023,"SREBF2/ERBB2/CSNK2A2/LRRK2",4
"GO:0003254","BP","GO:0003254","regulation of membrane depolarization","3/173","49/21081",0.00758863395358269,0.0149485886271548,0.00582160045630237,"SRC/PARP1/LRRK2",3
"GO:0003298","BP","GO:0003298","physiological muscle hypertrophy","3/173","49/21081",0.00758863395358269,0.0149485886271548,0.00582160045630237,"G6PD/PPARA/MTOR",3
"GO:0003301","BP","GO:0003301","physiological cardiac muscle hypertrophy","3/173","49/21081",0.00758863395358269,0.0149485886271548,0.00582160045630237,"G6PD/PPARA/MTOR",3
"GO:0014075","BP","GO:0014075","response to amine","3/173","49/21081",0.00758863395358269,0.0149485886271548,0.00582160045630237,"DRD2/DRD3/CDK1",3
"GO:0018198","BP","GO:0018198","peptidyl-cysteine modification","3/173","49/21081",0.00758863395358269,0.0149485886271548,0.00582160045630237,"NOS2/NOS1/ACE",3
"GO:0021575","BP","GO:0021575","hindbrain morphogenesis","3/173","49/21081",0.00758863395358269,0.0149485886271548,0.00582160045630237,"PTPN11/RORA/ABL1",3
"GO:0033574","BP","GO:0033574","response to testosterone","3/173","49/21081",0.00758863395358269,0.0149485886271548,0.00582160045630237,"SRD5A1/CDK4/SIRT1",3
"GO:0035722","BP","GO:0035722","interleukin-12-mediated signaling pathway","3/173","49/21081",0.00758863395358269,0.0149485886271548,0.00582160045630237,"MIF/MIF/TYK2",3
"GO:0042551","BP","GO:0042551","neuron maturation","3/173","49/21081",0.00758863395358269,0.0149485886271548,0.00582160045630237,"MTOR/LRRK2/APP",3
"GO:0045773","BP","GO:0045773","positive regulation of axon extension","3/173","49/21081",0.00758863395358269,0.0149485886271548,0.00582160045630237,"MAPT/MAPT/MAPT",3
"GO:0060999","BP","GO:0060999","positive regulation of dendritic spine development","3/173","49/21081",0.00758863395358269,0.0149485886271548,0.00582160045630237,"MTOR/IL2/PSEN1",3
"GO:0061049","BP","GO:0061049","cell growth involved in cardiac muscle cell development","3/173","49/21081",0.00758863395358269,0.0149485886271548,0.00582160045630237,"G6PD/PPARA/MTOR",3
"GO:0006401","BP","GO:0006401","RNA catabolic process","10/173","493/21081",0.00769235570666302,0.0151458847996345,0.00589843576941333,"PRKCA/MTOR/AKT1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/MAPK14/PPP2CA",10
"GO:0046474","BP","GO:0046474","glycerophospholipid biosynthetic process","7/173","275/21081",0.00775444892587969,0.0152610715544524,0.00594329426951214,"NR1H4/FABP5/HTR2A/CSNK2A1/CSNK2A2/PIK3CA/PIK3CG",7
"GO:0032465","BP","GO:0032465","regulation of cytokinesis","4/173","95/21081",0.00781530872560186,0.0153737253588344,0.00598716633364821,"BCL2L1/DRD2/DRD3/RHOA",4
"GO:1904064","BP","GO:1904064","positive regulation of cation transmembrane transport","5/173","150/21081",0.00799813467587052,0.0157260871067903,0.00612439061373558,"G6PD/NOS1/SNCA/F2/ABL1",5
"GO:0010712","BP","GO:0010712","regulation of collagen metabolic process","3/173","50/21081",0.00802503932259425,0.0157498346797704,0.00613363890366751,"PPARG/IL6/F2",3
"GO:0014014","BP","GO:0014014","negative regulation of gliogenesis","3/173","50/21081",0.00802503932259425,0.0157498346797704,0.00613363890366751,"TERT/DRD3/F2",3
"GO:0060711","BP","GO:0060711","labyrinthine layer development","3/173","50/21081",0.00802503932259425,0.0157498346797704,0.00613363890366751,"PLG/MAPK1/AKT1",3
"GO:1903053","BP","GO:1903053","regulation of extracellular matrix organization","3/173","50/21081",0.00802503932259425,0.0157498346797704,0.00613363890366751,"IL6/ABL1/DPP4",3
"GO:0032410","BP","GO:0032410","negative regulation of transporter activity","4/173","96/21081",0.00810397917192118,0.0158900819111643,0.00618825699281573,"DRD2/DRD3/SNCA/MMP9",4
"GO:0055013","BP","GO:0055013","cardiac muscle cell development","4/173","96/21081",0.00810397917192118,0.0158900819111643,0.00618825699281573,"G6PD/PPARA/MTOR/CDK1",4
"GO:0043588","BP","GO:0043588","skin development","10/173","498/21081",0.00822686402653162,0.0161235909818878,0.00627919511055919,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/EGFR/PSEN1",10
"GO:0001921","BP","GO:0001921","positive regulation of receptor recycling","2/173","17/21081",0.00839818102988496,0.0163564335977478,0.00636987368313524,"SNCA/PSEN1",2
"GO:0006991","BP","GO:0006991","response to sterol depletion","2/173","17/21081",0.00839818102988496,0.0163564335977478,0.00636987368313524,"NPC1L1/SREBF2",2
"GO:0021534","BP","GO:0021534","cell proliferation in hindbrain","2/173","17/21081",0.00839818102988496,0.0163564335977478,0.00636987368313524,"RORA/C5AR1",2
"GO:0030299","BP","GO:0030299","intestinal cholesterol absorption","2/173","17/21081",0.00839818102988496,0.0163564335977478,0.00636987368313524,"NPC1L1/AKR1C1",2
"GO:0032966","BP","GO:0032966","negative regulation of collagen biosynthetic process","2/173","17/21081",0.00839818102988496,0.0163564335977478,0.00636987368313524,"PPARG/IL6",2
"GO:0042953","BP","GO:0042953","lipoprotein transport","2/173","17/21081",0.00839818102988496,0.0163564335977478,0.00636987368313524,"PPARG/PRKCB",2
"GO:0045342","BP","GO:0045342","MHC class II biosynthetic process","2/173","17/21081",0.00839818102988496,0.0163564335977478,0.00636987368313524,"TLR4/SIRT1",2
"GO:0045722","BP","GO:0045722","positive regulation of gluconeogenesis","2/173","17/21081",0.00839818102988496,0.0163564335977478,0.00636987368313524,"PPARA/SIRT1",2
"GO:0055070","BP","GO:0055070","copper ion homeostasis","2/173","17/21081",0.00839818102988496,0.0163564335977478,0.00636987368313524,"XIAP/APP",2
"GO:0070875","BP","GO:0070875","positive regulation of glycogen metabolic process","2/173","17/21081",0.00839818102988496,0.0163564335977478,0.00636987368313524,"AKT1/INSR",2
"GO:0071872","BP","GO:0071872","cellular response to epinephrine stimulus","2/173","17/21081",0.00839818102988496,0.0163564335977478,0.00636987368313524,"SRD5A1/SNCA",2
"GO:0086103","BP","GO:0086103","G protein-coupled receptor signaling pathway involved in heart process","2/173","17/21081",0.00839818102988496,0.0163564335977478,0.00636987368313524,"SRC/NOS1",2
"GO:1903209","BP","GO:1903209","positive regulation of oxidative stress-induced cell death","2/173","17/21081",0.00839818102988496,0.0163564335977478,0.00636987368313524,"TLR4/MMP3",2
"GO:0006094","BP","GO:0006094","gluconeogenesis","4/173","97/21081",0.00839956180519787,0.0163564335977478,0.00636987368313524,"PPARA/SIRT1/OGT/EP300",4
"GO:0007528","BP","GO:0007528","neuromuscular junction development","3/173","51/21081",0.00847595366743785,0.0164825295802945,0.0064189806890099,"ERBB2/LRRK2/APP",3
"GO:0071349","BP","GO:0071349","cellular response to interleukin-12","3/173","51/21081",0.00847595366743785,0.0164825295802945,0.0064189806890099,"MIF/MIF/TYK2",3
"GO:1902743","BP","GO:1902743","regulation of lamellipodium organization","3/173","51/21081",0.00847595366743785,0.0164825295802945,0.0064189806890099,"SRC/MTOR/HDAC4",3
"GO:0050851","BP","GO:0050851","antigen receptor-mediated signaling pathway","9/173","424/21081",0.00850882296820109,0.0165388786788136,0.00644092536524877,"PRKCB/IKBKB/CSK/PIK3CA/MAPK1/CHUK/ABL1/CD38/PSEN1",9
"GO:0021795","BP","GO:0021795","cerebral cortex cell migration","3/173","52/21081",0.00894147885002961,0.0173560272424741,0.00675915691002695,"EGFR/RHOA/PSEN1",3
"GO:0070671","BP","GO:0070671","response to interleukin-12","3/173","52/21081",0.00894147885002961,0.0173560272424741,0.00675915691002695,"MIF/MIF/TYK2",3
"GO:2000677","BP","GO:2000677","regulation of transcription regulatory region DNA binding","3/173","52/21081",0.00894147885002961,0.0173560272424741,0.00675915691002695,"PARP1/EP300/PSEN1",3
"GO:0051492","BP","GO:0051492","regulation of stress fiber assembly","4/173","99/21081",0.0090117217010916,0.0174764059826281,0.00680603738457133,"MTOR/RHOA/ABL1/NOX4",4
"GO:1903725","BP","GO:1903725","regulation of phospholipid metabolic process","4/173","99/21081",0.0090117217010916,0.0174764059826281,0.00680603738457133,"NR1H4/SRC/HTR2A/PTK2",4
"GO:0009299","BP","GO:0009299","mRNA transcription","2/173","18/21081",0.00939735526584327,0.01814971023844,0.00706824998942852,"STAT3/C5AR1",2
"GO:0010713","BP","GO:0010713","negative regulation of collagen metabolic process","2/173","18/21081",0.00939735526584327,0.01814971023844,0.00706824998942852,"PPARG/IL6",2
"GO:0031293","BP","GO:0031293","membrane protein intracellular domain proteolysis","2/173","18/21081",0.00939735526584327,0.01814971023844,0.00706824998942852,"PSEN2/PSEN1",2
"GO:0032740","BP","GO:0032740","positive regulation of interleukin-17 production","2/173","18/21081",0.00939735526584327,0.01814971023844,0.00706824998942852,"IL6/IL2",2
"GO:0044872","BP","GO:0044872","lipoprotein localization","2/173","18/21081",0.00939735526584327,0.01814971023844,0.00706824998942852,"PPARG/PRKCB",2
"GO:0045187","BP","GO:0045187","regulation of circadian sleep/wake cycle, sleep","2/173","18/21081",0.00939735526584327,0.01814971023844,0.00706824998942852,"DRD2/DRD3",2
"GO:0051024","BP","GO:0051024","positive regulation of immunoglobulin secretion","2/173","18/21081",0.00939735526584327,0.01814971023844,0.00706824998942852,"IL6/IL2",2
"GO:0055089","BP","GO:0055089","fatty acid homeostasis","2/173","18/21081",0.00939735526584327,0.01814971023844,0.00706824998942852,"NR1H4/SIRT1",2
"GO:0097067","BP","GO:0097067","cellular response to thyroid hormone stimulus","2/173","18/21081",0.00939735526584327,0.01814971023844,0.00706824998942852,"CTSB/CTSB",2
"GO:0006656","BP","GO:0006656","phosphatidylcholine biosynthetic process","3/173","53/21081",0.00942171116611829,0.0181802228632319,0.00708013287114009,"FABP5/CSNK2A1/CSNK2A2",3
"GO:0010171","BP","GO:0010171","body morphogenesis","3/173","53/21081",0.00942171116611829,0.0181802228632319,0.00708013287114009,"PTPN11/MMP2/EP300",3
"GO:0061351","BP","GO:0061351","neural precursor cell proliferation","5/173","157/21081",0.00962958350598092,0.0185729007339596,0.0072330579216867,"RORA/DRD2/LRRK2/RHOA/C5AR1",5
"GO:1903363","BP","GO:1903363","negative regulation of cellular protein catabolic process","4/173","101/21081",0.00965229414171996,0.0186082567187696,0.00724682700868458,"CSNK2A1/CSNK2A2/OGT/PSEN1",4
"GO:0003179","BP","GO:0003179","heart valve morphogenesis","3/173","54/21081",0.0099167414519704,0.0190403228329969,0.00741509147501485,"MDM2/MTOR/NOS3",3
"GO:0006754","BP","GO:0006754","ATP biosynthetic process","3/173","54/21081",0.0099167414519704,0.0190403228329969,0.00741509147501485,"PARP1/STAT3/VCP",3
"GO:0006984","BP","GO:0006984","ER-nucleus signaling pathway","3/173","54/21081",0.0099167414519704,0.0190403228329969,0.00741509147501485,"SREBF2/GSK3B/CXCL8",3
"GO:0010524","BP","GO:0010524","positive regulation of calcium ion transport into cytosol","3/173","54/21081",0.0099167414519704,0.0190403228329969,0.00741509147501485,"SNCA/F2/ABL1",3
"GO:0032964","BP","GO:0032964","collagen biosynthetic process","3/173","54/21081",0.0099167414519704,0.0190403228329969,0.00741509147501485,"PPARG/IL6/F2",3
"GO:0055078","BP","GO:0055078","sodium ion homeostasis","3/173","54/21081",0.0099167414519704,0.0190403228329969,0.00741509147501485,"DRD2/AGTR1/DRD3",3
"GO:0090199","BP","GO:0090199","regulation of release of cytochrome c from mitochondria","3/173","54/21081",0.0099167414519704,0.0190403228329969,0.00741509147501485,"BCL2L1/AKT1/MMP9",3
"GO:1901185","BP","GO:1901185","negative regulation of ERBB signaling pathway","3/173","54/21081",0.0099167414519704,0.0190403228329969,0.00741509147501485,"ERBB2/EGFR/PSEN1",3
"GO:1903214","BP","GO:1903214","regulation of protein targeting to mitochondrion","3/173","54/21081",0.0099167414519704,0.0190403228329969,0.00741509147501485,"SREBF2/CSNK2A2/LRRK2",3
"GO:0055006","BP","GO:0055006","cardiac cell development","4/173","102/21081",0.00998338851317176,0.0191596286325505,0.00746155410198546,"G6PD/PPARA/MTOR/CDK1",4
"GO:0010522","BP","GO:0010522","regulation of calcium ion transport into cytosol","4/173","103/21081",0.0103217680349403,0.019791151796237,0.0077074954165524,"NOS1/SNCA/F2/ABL1",4
"GO:0045778","BP","GO:0045778","positive regulation of ossification","4/173","103/21081",0.0103217680349403,0.019791151796237,0.0077074954165524,"PTPN11/ALOX5/ALOX5/IL6",4
"GO:0060348","BP","GO:0060348","bone development","6/173","223/21081",0.0103773754442463,0.0198871389501035,0.00774487679567025,"SRD5A1/PTPN11/SRC/RHOA/MMP13/EP300",6
"GO:0032735","BP","GO:0032735","positive regulation of interleukin-12 production","3/173","55/21081",0.0104266551895175,0.0198871389501035,0.00774487679567025,"IDO1/TLR4/MAPK14",3
"GO:0035337","BP","GO:0035337","fatty-acyl-CoA metabolic process","3/173","55/21081",0.0104266551895175,0.0198871389501035,0.00774487679567025,"FASN/ACACA/ACACA",3
"GO:0010544","BP","GO:0010544","negative regulation of platelet activation","2/173","19/21081",0.0104467154946178,0.0198871389501035,0.00774487679567025,"NOS3/F2",2
"GO:0021756","BP","GO:0021756","striatum development","2/173","19/21081",0.0104467154946178,0.0198871389501035,0.00774487679567025,"DRD2/LRRK2",2
"GO:0032095","BP","GO:0032095","regulation of response to food","2/173","19/21081",0.0104467154946178,0.0198871389501035,0.00774487679567025,"PPARA/MTOR",2
"GO:0032305","BP","GO:0032305","positive regulation of icosanoid secretion","2/173","19/21081",0.0104467154946178,0.0198871389501035,0.00774487679567025,"MIF/MIF",2
"GO:0033033","BP","GO:0033033","negative regulation of myeloid cell apoptotic process","2/173","19/21081",0.0104467154946178,0.0198871389501035,0.00774487679567025,"MIF/MIF",2
"GO:0035313","BP","GO:0035313","wound healing, spreading of epidermal cells","2/173","19/21081",0.0104467154946178,0.0198871389501035,0.00774487679567025,"MTOR/MMP12",2
"GO:0061577","BP","GO:0061577","calcium ion transmembrane transport via high voltage-gated calcium channel","2/173","19/21081",0.0104467154946178,0.0198871389501035,0.00774487679567025,"G6PD/NOS1",2
"GO:0098856","BP","GO:0098856","intestinal lipid absorption","2/173","19/21081",0.0104467154946178,0.0198871389501035,0.00774487679567025,"NPC1L1/AKR1C1",2
"GO:1900272","BP","GO:1900272","negative regulation of long-term synaptic potentiation","2/173","19/21081",0.0104467154946178,0.0198871389501035,0.00774487679567025,"ABL1/APP",2
"GO:1902176","BP","GO:1902176","negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway","2/173","19/21081",0.0104467154946178,0.0198871389501035,0.00774487679567025,"AKT1/SIRT1",2
"GO:1904355","BP","GO:1904355","positive regulation of telomere capping","2/173","19/21081",0.0104467154946178,0.0198871389501035,0.00774487679567025,"MAPK3/MAPK1",2
"GO:2000757","BP","GO:2000757","negative regulation of peptidyl-lysine acetylation","2/173","19/21081",0.0104467154946178,0.0198871389501035,0.00774487679567025,"SNCA/SIRT1",2
"GO:2000846","BP","GO:2000846","regulation of corticosteroid hormone secretion","2/173","19/21081",0.0104467154946178,0.0198871389501035,0.00774487679567025,"PTPN11/AGTR1",2
"GO:0071901","BP","GO:0071901","negative regulation of protein serine/threonine kinase activity","5/173","161/21081",0.0106579059811185,0.0202800906913446,0.00789790850275452,"HMGCR/AKT1/SIRT1/ABL1/PPP2CA",5
"GO:0030641","BP","GO:0030641","regulation of cellular pH","4/173","104/21081",0.0106674911569031,0.020289243476133,0.00790147297679483,"MAPK3/MAPK1/LRRK2/CFTR",4
"GO:0017144","BP","GO:0017144","drug metabolic process","3/173","56/21081",0.0109515326099848,0.0208108506528737,0.00810460844689584,"NR1I2/NOS1/CBR1",3
"GO:0050798","BP","GO:0050798","activated T cell proliferation","3/173","56/21081",0.0109515326099848,0.0208108506528737,0.00810460844689584,"STAT5B/ABL1/IL2",3
"GO:0007044","BP","GO:0007044","cell-substrate junction assembly","4/173","105/21081",0.011020615252302,0.0209327645091779,0.00815208675934343,"SRC/PTK2/RHOA/ABL1",4
"GO:0043949","BP","GO:0043949","regulation of cAMP-mediated signaling","3/173","57/21081",0.0114914487960203,0.0217931239512359,0.00848714641249156,"PDE4A/PRKCA/NOS1",3
"GO:0048260","BP","GO:0048260","positive regulation of receptor-mediated endocytosis","3/173","57/21081",0.0114914487960203,0.0217931239512359,0.00848714641249156,"SERPINE1/DRD2/INSR",3
"GO:0099172","BP","GO:0099172","presynapse organization","3/173","57/21081",0.0114914487960203,0.0217931239512359,0.00848714641249156,"SNCA/APP/C5AR1",3
"GO:0002031","BP","GO:0002031","G protein-coupled receptor internalization","2/173","20/21081",0.0115453805634813,0.0217931239512359,0.00848714641249156,"DRD2/DRD3",2
"GO:0032769","BP","GO:0032769","negative regulation of monooxygenase activity","2/173","20/21081",0.0115453805634813,0.0217931239512359,0.00848714641249156,"CNR1/SNCA",2
"GO:0033189","BP","GO:0033189","response to vitamin A","2/173","20/21081",0.0115453805634813,0.0217931239512359,0.00848714641249156,"PPARG/CYP26A1",2
"GO:0035930","BP","GO:0035930","corticosteroid hormone secretion","2/173","20/21081",0.0115453805634813,0.0217931239512359,0.00848714641249156,"PTPN11/AGTR1",2
"GO:0050665","BP","GO:0050665","hydrogen peroxide biosynthetic process","2/173","20/21081",0.0115453805634813,0.0217931239512359,0.00848714641249156,"MAOB/STAT3",2
"GO:0051412","BP","GO:0051412","response to corticosterone","2/173","20/21081",0.0115453805634813,0.0217931239512359,0.00848714641249156,"CCND1/MAOB",2
"GO:0051767","BP","GO:0051767","nitric-oxide synthase biosynthetic process","2/173","20/21081",0.0115453805634813,0.0217931239512359,0.00848714641249156,"TLR4/LRRK2",2
"GO:0051769","BP","GO:0051769","regulation of nitric-oxide synthase biosynthetic process","2/173","20/21081",0.0115453805634813,0.0217931239512359,0.00848714641249156,"TLR4/LRRK2",2
"GO:0071871","BP","GO:0071871","response to epinephrine","2/173","20/21081",0.0115453805634813,0.0217931239512359,0.00848714641249156,"SRD5A1/SNCA",2
"GO:1901386","BP","GO:1901386","negative regulation of voltage-gated calcium channel activity","2/173","20/21081",0.0115453805634813,0.0217931239512359,0.00848714641249156,"DRD2/DRD3",2
"GO:1905939","BP","GO:1905939","regulation of gonad development","2/173","20/21081",0.0115453805634813,0.0217931239512359,0.00848714641249156,"SRC/INSR",2
"GO:0071347","BP","GO:0071347","cellular response to interleukin-1","6/173","229/21081",0.0117161238038067,0.0221055994859568,0.00860883734672532,"MAPK3/RORA/IL6/IKBKB/CHUK/CXCL8",6
"GO:0006749","BP","GO:0006749","glutathione metabolic process","3/173","58/21081",0.0120464737823427,0.0226785410284333,0.00883196454811589,"G6PD/GSR/GLO1",3
"GO:0050879","BP","GO:0050879","multicellular organismal movement","3/173","58/21081",0.0120464737823427,0.0226785410284333,0.00883196454811589,"DRD3/MTOR/CHUK",3
"GO:0050881","BP","GO:0050881","musculoskeletal movement","3/173","58/21081",0.0120464737823427,0.0226785410284333,0.00883196454811589,"DRD3/MTOR/CHUK",3
"GO:0072348","BP","GO:0072348","sulfur compound transport","3/173","58/21081",0.0120464737823427,0.0226785410284333,0.00883196454811589,"ABCC1/ABCC1/ABCG2",3
"GO:2001258","BP","GO:2001258","negative regulation of cation channel activity","3/173","58/21081",0.0120464737823427,0.0226785410284333,0.00883196454811589,"DRD2/DRD3/MMP9",3
"GO:0002042","BP","GO:0002042","cell migration involved in sprouting angiogenesis","4/173","108/21081",0.0121249508567196,0.0228060717973447,0.00888163031931375,"PTGS2/AKT1/RHOA/ABL1",4
"GO:0150115","BP","GO:0150115","cell-substrate junction organization","4/173","108/21081",0.0121249508567196,0.0228060717973447,0.00888163031931375,"SRC/PTK2/RHOA/ABL1",4
"GO:0043484","BP","GO:0043484","regulation of RNA splicing","5/173","167/21081",0.0123375445127011,0.0231956755019765,0.00903335816207085,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",5
"GO:0120162","BP","GO:0120162","positive regulation of cold-induced thermogenesis","4/173","109/21081",0.0125082308740536,0.0235061800017044,0.00915428149352277,"FABP4/FABP5/IGF1R/OGT",4
"GO:0001541","BP","GO:0001541","ovarian follicle development","3/173","59/21081",0.0126166726549272,0.023668098062157,0.00921733910237969,"ESR1/BCL2L1/SRC",3
"GO:0032210","BP","GO:0032210","regulation of telomere maintenance via telomerase","3/173","59/21081",0.0126166726549272,0.023668098062157,0.00921733910237969,"MAPK3/SRC/MAPK1",3
"GO:1900408","BP","GO:1900408","negative regulation of cellular response to oxidative stress","3/173","59/21081",0.0126166726549272,0.023668098062157,0.00921733910237969,"AKT1/LRRK2/SIRT1",3
"GO:1903202","BP","GO:1903202","negative regulation of oxidative stress-induced cell death","3/173","59/21081",0.0126166726549272,0.023668098062157,0.00921733910237969,"AKT1/LRRK2/SIRT1",3
"GO:0007194","BP","GO:0007194","negative regulation of adenylate cyclase activity","2/173","21/21081",0.0126924802557815,0.0236848259142801,0.00922385362184248,"DRD2/DRD3",2
"GO:0010988","BP","GO:0010988","regulation of low-density lipoprotein particle clearance","2/173","21/21081",0.0126924802557815,0.0236848259142801,0.00922385362184248,"NR1H4/CSK",2
"GO:0030878","BP","GO:0030878","thyroid gland development","2/173","21/21081",0.0126924802557815,0.0236848259142801,0.00922385362184248,"MAPK3/MAPK1",2
"GO:0043950","BP","GO:0043950","positive regulation of cAMP-mediated signaling","2/173","21/21081",0.0126924802557815,0.0236848259142801,0.00922385362184248,"PRKCA/NOS1",2
"GO:0044241","BP","GO:0044241","lipid digestion","2/173","21/21081",0.0126924802557815,0.0236848259142801,0.00922385362184248,"NPC1L1/AKR1C1",2
"GO:0045780","BP","GO:0045780","positive regulation of bone resorption","2/173","21/21081",0.0126924802557815,0.0236848259142801,0.00922385362184248,"PRKCA/EGFR",2
"GO:0046852","BP","GO:0046852","positive regulation of bone remodeling","2/173","21/21081",0.0126924802557815,0.0236848259142801,0.00922385362184248,"PRKCA/EGFR",2
"GO:0060438","BP","GO:0060438","trachea development","2/173","21/21081",0.0126924802557815,0.0236848259142801,0.00922385362184248,"MAPK3/MAPK1",2
"GO:0070262","BP","GO:0070262","peptidyl-serine dephosphorylation","2/173","21/21081",0.0126924802557815,0.0236848259142801,0.00922385362184248,"PPP1CA/PPP2CA",2
"GO:0070932","BP","GO:0070932","histone H3 deacetylation","2/173","21/21081",0.0126924802557815,0.0236848259142801,0.00922385362184248,"HDAC4/SIRT1",2
"GO:0071071","BP","GO:0071071","regulation of phospholipid biosynthetic process","2/173","21/21081",0.0126924802557815,0.0236848259142801,0.00922385362184248,"NR1H4/HTR2A",2
"GO:0097062","BP","GO:0097062","dendritic spine maintenance","2/173","21/21081",0.0126924802557815,0.0236848259142801,0.00922385362184248,"IGF1R/INSR",2
"GO:0034446","BP","GO:0034446","substrate adhesion-dependent cell spreading","4/173","110/21081",0.0128991824158511,0.0240494190807158,0.00936584132362666,"SRC/PTK2/RHOA/ABL1",4
"GO:0110020","BP","GO:0110020","regulation of actomyosin structure organization","4/173","110/21081",0.0128991824158511,0.0240494190807158,0.00936584132362666,"MTOR/RHOA/ABL1/NOX4",4
"GO:0007519","BP","GO:0007519","skeletal muscle tissue development","5/173","169/21081",0.0129351111207863,0.0240952596020258,0.00938369352402041,"HMGCR/HDAC4/RHOA/MAPK14/EP300",5
"GO:0010770","BP","GO:0010770","positive regulation of cell morphogenesis involved in differentiation","5/173","169/21081",0.0129351111207863,0.0240952596020258,0.00938369352402041,"RHOA/ABL1/MAPT/MAPT/MAPT",5
"GO:0038066","BP","GO:0038066","p38MAPK cascade","3/173","60/21081",0.0132021056487471,0.0245710674119696,0.00956899282100214,"PRMT1/XDH/MAPK14",3
"GO:0097755","BP","GO:0097755","positive regulation of blood vessel diameter","3/173","60/21081",0.0132021056487471,0.0245710674119696,0.00956899282100214,"NOS3/NOS1/EGFR",3
"GO:0030902","BP","GO:0030902","hindbrain development","5/173","170/21081",0.0132411124651747,0.0246328751596003,0.00959306332162162,"PTPN11/RORA/ABL1/C5AR1/PSEN1",5
"GO:0060996","BP","GO:0060996","dendritic spine development","4/173","111/21081",0.0132978563019394,0.0247276111277639,0.00962995743712944,"MTOR/LRRK2/IL2/PSEN1",4
"GO:0045165","BP","GO:0045165","cell fate commitment","7/173","307/21081",0.0136181673044478,0.0253121578637789,0.0098576041822498,"RORA/PPARG/IL6/MTOR/RHOA/STAT3/PSEN1",7
"GO:0032231","BP","GO:0032231","regulation of actin filament bundle assembly","4/173","112/21081",0.0137043022480891,0.0254611194805993,0.00991561601454264,"MTOR/RHOA/ABL1/NOX4",4
"GO:0120178","BP","GO:0120178","steroid hormone biosynthetic process","3/173","61/21081",0.0138028282440898,0.0255882577311148,0.00996512892279608,"CYP19A1/SRD5A1/AKR1B1",3
"GO:1902883","BP","GO:1902883","negative regulation of response to oxidative stress","3/173","61/21081",0.0138028282440898,0.0255882577311148,0.00996512892279608,"AKT1/LRRK2/SIRT1",3
"GO:2000725","BP","GO:2000725","regulation of cardiac muscle cell differentiation","3/173","61/21081",0.0138028282440898,0.0255882577311148,0.00996512892279608,"G6PD/PPARA/MTOR",3
"GO:0045580","BP","GO:0045580","regulation of T cell differentiation","5/173","172/21081",0.0138677151667161,0.0255882577311148,0.00996512892279608,"ERBB2/RHOA/STAT5B/ABL1/IL2",5
"GO:0051017","BP","GO:0051017","actin filament bundle assembly","5/173","172/21081",0.0138677151667161,0.0255882577311148,0.00996512892279608,"SRC/MTOR/RHOA/ABL1/NOX4",5
"GO:0090263","BP","GO:0090263","positive regulation of canonical Wnt signaling pathway","5/173","172/21081",0.0138677151667161,0.0255882577311148,0.00996512892279608,"XIAP/SRC/LRRK2/EGFR/VCP",5
"GO:0032303","BP","GO:0032303","regulation of icosanoid secretion","2/173","22/21081",0.0138871551724996,0.0255882577311148,0.00996512892279608,"MIF/MIF",2
"GO:0032727","BP","GO:0032727","positive regulation of interferon-alpha production","2/173","22/21081",0.0138871551724996,0.0255882577311148,0.00996512892279608,"CHUK/TLR4",2
"GO:0036120","BP","GO:0036120","cellular response to platelet-derived growth factor stimulus","2/173","22/21081",0.0138871551724996,0.0255882577311148,0.00996512892279608,"SRC/CCNA2",2
"GO:0042749","BP","GO:0042749","regulation of circadian sleep/wake cycle","2/173","22/21081",0.0138871551724996,0.0255882577311148,0.00996512892279608,"DRD2/DRD3",2
"GO:0043651","BP","GO:0043651","linoleic acid metabolic process","2/173","22/21081",0.0138871551724996,0.0255882577311148,0.00996512892279608,"ALOX5/ALOX5",2
"GO:0045943","BP","GO:0045943","positive regulation of transcription by RNA polymerase I","2/173","22/21081",0.0138871551724996,0.0255882577311148,0.00996512892279608,"ERBB2/MTOR",2
"GO:0051546","BP","GO:0051546","keratinocyte migration","2/173","22/21081",0.0138871551724996,0.0255882577311148,0.00996512892279608,"MTOR/MMP9",2
"GO:0055093","BP","GO:0055093","response to hyperoxia","2/173","22/21081",0.0138871551724996,0.0255882577311148,0.00996512892279608,"PPARG/CDK4",2
"GO:0090594","BP","GO:0090594","inflammatory response to wounding","2/173","22/21081",0.0138871551724996,0.0255882577311148,0.00996512892279608,"ALOX5/ALOX5",2
"GO:1904886","BP","GO:1904886","beta-catenin destruction complex disassembly","2/173","22/21081",0.0138871551724996,0.0255882577311148,0.00996512892279608,"GSK3B/PPP1CA",2
"GO:2000193","BP","GO:2000193","positive regulation of fatty acid transport","2/173","22/21081",0.0138871551724996,0.0255882577311148,0.00996512892279608,"MIF/MIF",2
"GO:2000269","BP","GO:2000269","regulation of fibroblast apoptotic process","2/173","22/21081",0.0138871551724996,0.0255882577311148,0.00996512892279608,"PIK3CA/PIK3CG",2
"GO:2000831","BP","GO:2000831","regulation of steroid hormone secretion","2/173","22/21081",0.0138871551724996,0.0255882577311148,0.00996512892279608,"PTPN11/AGTR1",2
"GO:0019730","BP","GO:0019730","antimicrobial humoral response","5/173","173/21081",0.0141883810553517,0.0261319597330686,0.0101768690342951,"F2/CXCL8/CTSG/ELANE/ELANE",5
"GO:0061178","BP","GO:0061178","regulation of insulin secretion involved in cellular response to glucose stimulus","3/173","62/21081",0.0144188912614634,0.0265450038864637,0.010337725560075,"NR1H4/HMGCR/CFTR",3
"GO:0006885","BP","GO:0006885","regulation of pH","4/173","114/21081",0.0145407036496176,0.0267576655726398,0.0104205448415577,"MAPK3/MAPK1/LRRK2/CFTR",4
"GO:0007265","BP","GO:0007265","Ras protein signal transduction","8/173","386/21081",0.014612255699926,0.0268776945753184,0.0104672891138226,"AGTR1/CDK2/CCNA2/CHUK/RHOA/ABL1/MAPK14/OGT",8
"GO:0050852","BP","GO:0050852","T cell receptor signaling pathway","7/173","312/21081",0.014761384473225,0.0271402521102263,0.0105695399084059,"IKBKB/CSK/PIK3CA/MAPK1/CHUK/ABL1/PSEN1",7
"GO:1903038","BP","GO:1903038","negative regulation of leukocyte cell-cell adhesion","5/173","175/21081",0.0148446005860167,0.0272814480493014,0.0106245274636761,"PPARA/IDO1/ERBB2/AKT1/IL2",5
"GO:1902414","BP","GO:1902414","protein localization to cell junction","4/173","115/21081",0.0149707529968883,0.0275013962316378,0.0107101844089965,"MAPK10/MAPT/MAPT/MAPT",4
"GO:0046888","BP","GO:0046888","negative regulation of hormone secretion","3/173","63/21081",0.0150503409551152,0.0276237143491509,0.0107578201575269,"HMGCR/PTPN11/DRD2",3
"GO:0098930","BP","GO:0098930","axonal transport","3/173","63/21081",0.0150503409551152,0.0276237143491509,0.0107578201575269,"MAPT/MAPT/MAPT",3
"GO:0006144","BP","GO:0006144","purine nucleobase metabolic process","2/173","23/21081",0.0151285566149978,0.0276478438955378,0.0107672172037471,"TTR/XDH",2
"GO:0010715","BP","GO:0010715","regulation of extracellular matrix disassembly","2/173","23/21081",0.0151285566149978,0.0276478438955378,0.0107672172037471,"IL6/DPP4",2
"GO:0033194","BP","GO:0033194","response to hydroperoxide","2/173","23/21081",0.0151285566149978,0.0276478438955378,0.0107672172037471,"CHUK/CD38",2
"GO:0035855","BP","GO:0035855","megakaryocyte development","2/173","23/21081",0.0151285566149978,0.0276478438955378,0.0107672172037471,"PTPN11/EP300",2
"GO:0036119","BP","GO:0036119","response to platelet-derived growth factor","2/173","23/21081",0.0151285566149978,0.0276478438955378,0.0107672172037471,"SRC/CCNA2",2
"GO:0043984","BP","GO:0043984","histone H4-K16 acetylation","2/173","23/21081",0.0151285566149978,0.0276478438955378,0.0107672172037471,"SIRT1/OGT",2
"GO:0046827","BP","GO:0046827","positive regulation of protein export from nucleus","2/173","23/21081",0.0151285566149978,0.0276478438955378,0.0107672172037471,"MDM2/GSK3B",2
"GO:0070207","BP","GO:0070207","protein homotrimerization","2/173","23/21081",0.0151285566149978,0.0276478438955378,0.0107672172037471,"MIF/MIF",2
"GO:0071397","BP","GO:0071397","cellular response to cholesterol","2/173","23/21081",0.0151285566149978,0.0276478438955378,0.0107672172037471,"CES1/CES1",2
"GO:0090201","BP","GO:0090201","negative regulation of release of cytochrome c from mitochondria","2/173","23/21081",0.0151285566149978,0.0276478438955378,0.0107672172037471,"BCL2L1/AKT1",2
"GO:0061572","BP","GO:0061572","actin filament bundle organization","5/173","176/21081",0.015180216622627,0.0277303269258565,0.0107993395170248,"SRC/MTOR/RHOA/ABL1/NOX4",5
"GO:0021549","BP","GO:0021549","cerebellum development","4/173","116/21081",0.0154087621850836,0.0281357243336571,0.0109572180828948,"PTPN11/RORA/ABL1/PSEN1",4
"GO:0002702","BP","GO:0002702","positive regulation of production of molecular mediator of immune response","5/173","177/21081",0.0155208778298072,0.0283282688568946,0.0110322029066996,"IL6/TLR4/MIF/MIF/IL2",5
"GO:0003170","BP","GO:0003170","heart valve development","3/173","64/21081",0.0156972191051745,0.0286132492397625,0.0111431860883444,"MDM2/MTOR/NOS3",3
"GO:0007566","BP","GO:0007566","embryo implantation","3/173","64/21081",0.0156972191051745,0.0286132492397625,0.0111431860883444,"PTGS2/MMP9/MMP2",3
"GO:0009206","BP","GO:0009206","purine ribonucleoside triphosphate biosynthetic process","3/173","64/21081",0.0156972191051745,0.0286132492397625,0.0111431860883444,"PARP1/STAT3/VCP",3
"GO:0000723","BP","GO:0000723","telomere maintenance","5/173","178/21081",0.0158666144894944,0.0289096247709526,0.0112586070133994,"MAPK3/TERT/SRC/MAPK1/PARP1",5
"GO:0048762","BP","GO:0048762","mesenchymal cell differentiation","6/173","245/21081",0.0158743201725022,0.0289112672151572,0.0112592466492988,"MAPK3/IL6/GSK3B/MTOR/MAPK1/PPP2CA",6
"GO:0008654","BP","GO:0008654","phospholipid biosynthetic process","7/173","317/21081",0.0159716135814665,0.029076000903021,0.0113234007802577,"NR1H4/FABP5/HTR2A/CSNK2A1/CSNK2A2/PIK3CA/PIK3CG",7
"GO:0006520","BP","GO:0006520","cellular amino acid metabolic process","8/173","393/21081",0.0161091519522826,0.0293012785296441,0.0114111332322406,"NR1H4/NOS2/IDO1/NQO1/NOS3/NOS1/NOX4/TYR",8
"GO:0031589","BP","GO:0031589","cell-substrate adhesion","8/173","393/21081",0.0161091519522826,0.0293012785296441,0.0114111332322406,"PLG/SERPINE1/SRC/GSK3B/PTK2/RHOA/ABL1/MMP12",8
"GO:0030593","BP","GO:0030593","neutrophil chemotaxis","4/173","118/21081",0.0163088356407342,0.0296056585936121,0.0115296714543752,"PIK3CG/CXCL8/DPP4/C5AR1",4
"GO:0032088","BP","GO:0032088","negative regulation of NF-kappaB transcription factor activity","4/173","118/21081",0.0163088356407342,0.0296056585936121,0.0115296714543752,"NR1H4/CHUK/SIRT1/CYP1B1",4
"GO:1901606","BP","GO:1901606","alpha-amino acid catabolic process","4/173","118/21081",0.0163088356407342,0.0296056585936121,0.0115296714543752,"NOS2/IDO1/NOS3/NOS1",4
"GO:0001836","BP","GO:0001836","release of cytochrome c from mitochondria","3/173","65/21081",0.0163595631084425,0.0296056585936121,0.0115296714543752,"BCL2L1/AKT1/MMP9",3
"GO:0009145","BP","GO:0009145","purine nucleoside triphosphate biosynthetic process","3/173","65/21081",0.0163595631084425,0.0296056585936121,0.0115296714543752,"PARP1/STAT3/VCP",3
"GO:0048645","BP","GO:0048645","animal organ formation","3/173","65/21081",0.0163595631084425,0.0296056585936121,0.0115296714543752,"MAPK3/MAPK1/PIM1",3
"GO:0002029","BP","GO:0002029","desensitization of G protein-coupled receptor signaling pathway","2/173","24/21081",0.0164158464689457,0.0296056585936121,0.0115296714543752,"DRD2/DRD3",2
"GO:0006925","BP","GO:0006925","inflammatory cell apoptotic process","2/173","24/21081",0.0164158464689457,0.0296056585936121,0.0115296714543752,"IL6/SIRT1",2
"GO:0010640","BP","GO:0010640","regulation of platelet-derived growth factor receptor signaling pathway","2/173","24/21081",0.0164158464689457,0.0296056585936121,0.0115296714543752,"SRC/SNCA",2
"GO:0010866","BP","GO:0010866","regulation of triglyceride biosynthetic process","2/173","24/21081",0.0164158464689457,0.0296056585936121,0.0115296714543752,"NR1H3/NR1H2",2
"GO:0019370","BP","GO:0019370","leukotriene biosynthetic process","2/173","24/21081",0.0164158464689457,0.0296056585936121,0.0115296714543752,"ALOX5/ALOX5",2
"GO:0022401","BP","GO:0022401","negative adaptation of signaling pathway","2/173","24/21081",0.0164158464689457,0.0296056585936121,0.0115296714543752,"DRD2/DRD3",2
"GO:0031280","BP","GO:0031280","negative regulation of cyclase activity","2/173","24/21081",0.0164158464689457,0.0296056585936121,0.0115296714543752,"DRD2/DRD3",2
"GO:0032098","BP","GO:0032098","regulation of appetite","2/173","24/21081",0.0164158464689457,0.0296056585936121,0.0115296714543752,"PPARA/HTR4",2
"GO:0032469","BP","GO:0032469","endoplasmic reticulum calcium ion homeostasis","2/173","24/21081",0.0164158464689457,0.0296056585936121,0.0115296714543752,"APP/PSEN1",2
"GO:0042574","BP","GO:0042574","retinal metabolic process","2/173","24/21081",0.0164158464689457,0.0296056585936121,0.0115296714543752,"AKR1C1/CYP1B1",2
"GO:0046039","BP","GO:0046039","GTP metabolic process","2/173","24/21081",0.0164158464689457,0.0296056585936121,0.0115296714543752,"LRRK2/RHOA",2
"GO:0051004","BP","GO:0051004","regulation of lipoprotein lipase activity","2/173","24/21081",0.0164158464689457,0.0296056585936121,0.0115296714543752,"NR1H3/NR1H2",2
"GO:1903077","BP","GO:1903077","negative regulation of protein localization to plasma membrane","2/173","24/21081",0.0164158464689457,0.0296056585936121,0.0115296714543752,"BCL2L1/CSK",2
"GO:1903978","BP","GO:1903978","regulation of microglial cell activation","2/173","24/21081",0.0164158464689457,0.0296056585936121,0.0115296714543752,"IL6/LRRK2",2
"GO:0060538","BP","GO:0060538","skeletal muscle organ development","5/173","180/21081",0.0165734334286724,0.0298771822818961,0.0116354140409857,"HMGCR/HDAC4/RHOA/MAPK14/EP300",5
"GO:0048259","BP","GO:0048259","regulation of receptor-mediated endocytosis","4/173","119/21081",0.0167709849039234,0.0302076790405979,0.0117641231873307,"SERPINE1/DRD2/DRD3/INSR",4
"GO:1903008","BP","GO:1903008","organelle disassembly","4/173","119/21081",0.0167709849039234,0.0302076790405979,0.0117641231873307,"SREBF2/CSNK2A2/CDK1/VCP",4
"GO:0002011","BP","GO:0002011","morphogenesis of an epithelial sheet","3/173","66/21081",0.0170374060678416,0.0306226473698219,0.0119257290669904,"MTOR/RHOA/MMP12",3
"GO:0035384","BP","GO:0035384","thioester biosynthetic process","3/173","66/21081",0.0170374060678416,0.0306226473698219,0.0119257290669904,"FASN/ACACA/ACACA",3
"GO:0055081","BP","GO:0055081","anion homeostasis","3/173","66/21081",0.0170374060678416,0.0306226473698219,0.0119257290669904,"NR1H4/SIRT1/CETP",3
"GO:0071616","BP","GO:0071616","acyl-CoA biosynthetic process","3/173","66/21081",0.0170374060678416,0.0306226473698219,0.0119257290669904,"FASN/ACACA/ACACA",3
"GO:1903749","BP","GO:1903749","positive regulation of establishment of protein localization to mitochondrion","3/173","66/21081",0.0170374060678416,0.0306226473698219,0.0119257290669904,"SREBF2/MAPK8/CSNK2A2",3
"GO:0007229","BP","GO:0007229","integrin-mediated signaling pathway","4/173","120/21081",0.0172412639992279,0.03097595379819,0.0120633212448142,"PTPN11/SRC/PTK2/ABL1",4
"GO:1903707","BP","GO:1903707","negative regulation of hemopoiesis","5/173","182/21081",0.0173009081876771,0.031069974171361,0.0120999366779501,"ERBB2/PRMT1/TLR4/STAT5B/IL2",5
"GO:0006790","BP","GO:0006790","sulfur compound metabolic process","8/173","399/21081",0.0174781170530042,0.031374955368912,0.0122187090064361,"G6PD/GSR/STAT5B/NOX4/GLO1/FASN/ACACA/ACACA",8
"GO:0002066","BP","GO:0002066","columnar/cuboidal epithelial cell development","3/173","67/21081",0.0177307768805442,0.0315004550680524,0.0122675837948194,"SRC/GSK3B/FASN",3
"GO:0043954","BP","GO:0043954","cellular component maintenance","3/173","67/21081",0.0177307768805442,0.0315004550680524,0.0122675837948194,"IGF1R/INSR/SIRT1",3
"GO:0048857","BP","GO:0048857","neural nucleus development","3/173","67/21081",0.0177307768805442,0.0315004550680524,0.0122675837948194,"G6PD/RHOA/MAOB",3
"GO:0140115","BP","GO:0140115","export across plasma membrane","3/173","67/21081",0.0177307768805442,0.0315004550680524,0.0122675837948194,"ABCC1/ABCC1/ABCG2",3
"GO:0006590","BP","GO:0006590","thyroid hormone generation","2/173","25/21081",0.0177481970894134,0.0315004550680524,0.0122675837948194,"CTSB/CTSB",2
"GO:0006907","BP","GO:0006907","pinocytosis","2/173","25/21081",0.0177481970894134,0.0315004550680524,0.0122675837948194,"NR1H3/NR1H2",2
"GO:0010226","BP","GO:0010226","response to lithium ion","2/173","25/21081",0.0177481970894134,0.0315004550680524,0.0122675837948194,"FABP4/PTGS2",2
"GO:0021544","BP","GO:0021544","subpallium development","2/173","25/21081",0.0177481970894134,0.0315004550680524,0.0122675837948194,"DRD2/LRRK2",2
"GO:0021895","BP","GO:0021895","cerebral cortex neuron differentiation","2/173","25/21081",0.0177481970894134,0.0315004550680524,0.0122675837948194,"DRD2/PSEN1",2
"GO:0023058","BP","GO:0023058","adaptation of signaling pathway","2/173","25/21081",0.0177481970894134,0.0315004550680524,0.0122675837948194,"DRD2/DRD3",2
"GO:0032104","BP","GO:0032104","regulation of response to extracellular stimulus","2/173","25/21081",0.0177481970894134,0.0315004550680524,0.0122675837948194,"PPARA/MTOR",2
"GO:0032107","BP","GO:0032107","regulation of response to nutrient levels","2/173","25/21081",0.0177481970894134,0.0315004550680524,0.0122675837948194,"PPARA/MTOR",2
"GO:0035809","BP","GO:0035809","regulation of urine volume","2/173","25/21081",0.0177481970894134,0.0315004550680524,0.0122675837948194,"DRD2/AKR1B1",2
"GO:0035929","BP","GO:0035929","steroid hormone secretion","2/173","25/21081",0.0177481970894134,0.0315004550680524,0.0122675837948194,"PTPN11/AGTR1",2
"GO:0035970","BP","GO:0035970","peptidyl-threonine dephosphorylation","2/173","25/21081",0.0177481970894134,0.0315004550680524,0.0122675837948194,"PPP1CA/PPP2CA",2
"GO:0042438","BP","GO:0042438","melanin biosynthetic process","2/173","25/21081",0.0177481970894134,0.0315004550680524,0.0122675837948194,"MC1R/TYR",2
"GO:0044346","BP","GO:0044346","fibroblast apoptotic process","2/173","25/21081",0.0177481970894134,0.0315004550680524,0.0122675837948194,"PIK3CA/PIK3CG",2
"GO:0048714","BP","GO:0048714","positive regulation of oligodendrocyte differentiation","2/173","25/21081",0.0177481970894134,0.0315004550680524,0.0122675837948194,"PPARG/MTOR",2
"GO:0060749","BP","GO:0060749","mammary gland alveolus development","2/173","25/21081",0.0177481970894134,0.0315004550680524,0.0122675837948194,"ESR1/CCND1",2
"GO:0061377","BP","GO:0061377","mammary gland lobule development","2/173","25/21081",0.0177481970894134,0.0315004550680524,0.0122675837948194,"ESR1/CCND1",2
"GO:0062149","BP","GO:0062149","detection of stimulus involved in sensory perception of pain","2/173","25/21081",0.0177481970894134,0.0315004550680524,0.0122675837948194,"BACE1/HTR2A",2
"GO:0070206","BP","GO:0070206","protein trimerization","2/173","25/21081",0.0177481970894134,0.0315004550680524,0.0122675837948194,"MIF/MIF",2
"GO:0090208","BP","GO:0090208","positive regulation of triglyceride metabolic process","2/173","25/21081",0.0177481970894134,0.0315004550680524,0.0122675837948194,"NR1H3/NR1H2",2
"GO:0097164","BP","GO:0097164","ammonium ion metabolic process","2/173","25/21081",0.0177481970894134,0.0315004550680524,0.0122675837948194,"SRD5A1/HTR1A",2
"GO:1902894","BP","GO:1902894","negative regulation of pri-miRNA transcription by RNA polymerase II","2/173","25/21081",0.0177481970894134,0.0315004550680524,0.0122675837948194,"PPARA/HDAC4",2
"GO:2000679","BP","GO:2000679","positive regulation of transcription regulatory region DNA binding","2/173","25/21081",0.0177481970894134,0.0315004550680524,0.0122675837948194,"PARP1/EP300",2
"GO:2000726","BP","GO:2000726","negative regulation of cardiac muscle cell differentiation","2/173","25/21081",0.0177481970894134,0.0315004550680524,0.0122675837948194,"G6PD/PPARA",2
"GO:0009166","BP","GO:0009166","nucleotide catabolic process","3/173","68/21081",0.0184397003247962,0.0327004535392567,0.0127349129736313,"PDE4A/XDH/VCP",3
"GO:0061098","BP","GO:0061098","positive regulation of protein tyrosine kinase activity","3/173","68/21081",0.0184397003247962,0.0327004535392567,0.0127349129736313,"SRC/ACE/NOX4",3
"GO:0055002","BP","GO:0055002","striated muscle cell development","5/173","186/21081",0.0188187334894878,0.0333586977875818,0.0129912605869068,"G6PD/PPARA/MTOR/HDAC4/CDK1",5
"GO:0006813","BP","GO:0006813","potassium ion transport","6/173","255/21081",0.0189380211426864,0.0335561517244682,0.0130681573400215,"DRD2/DRD3/CDK2/HTR2A/NOS3/NOS1",6
"GO:0001919","BP","GO:0001919","regulation of receptor recycling","2/173","26/21081",0.0191247911871205,0.0336485456538613,0.0131041393684879,"SNCA/PSEN1",2
"GO:0003071","BP","GO:0003071","renal system process involved in regulation of systemic arterial blood pressure","2/173","26/21081",0.0191247911871205,0.0336485456538613,0.0131041393684879,"AGTR1/RHOA",2
"GO:0006582","BP","GO:0006582","melanin metabolic process","2/173","26/21081",0.0191247911871205,0.0336485456538613,0.0131041393684879,"MC1R/TYR",2
"GO:0007530","BP","GO:0007530","sex determination","2/173","26/21081",0.0191247911871205,0.0336485456538613,0.0131041393684879,"SRD5A1/INSR",2
"GO:0009235","BP","GO:0009235","cobalamin metabolic process","2/173","26/21081",0.0191247911871205,0.0336485456538613,0.0131041393684879,"ABCC1/ABCC1",2
"GO:0010592","BP","GO:0010592","positive regulation of lamellipodium assembly","2/173","26/21081",0.0191247911871205,0.0336485456538613,0.0131041393684879,"MTOR/HDAC4",2
"GO:0021697","BP","GO:0021697","cerebellar cortex formation","2/173","26/21081",0.0191247911871205,0.0336485456538613,0.0131041393684879,"PTPN11/RORA",2
"GO:0035902","BP","GO:0035902","response to immobilization stress","2/173","26/21081",0.0191247911871205,0.0336485456538613,0.0131041393684879,"MDM2/PPARG",2
"GO:0045056","BP","GO:0045056","transcytosis","2/173","26/21081",0.0191247911871205,0.0336485456538613,0.0131041393684879,"IGF1R/SRC",2
"GO:0060765","BP","GO:0060765","regulation of androgen receptor signaling pathway","2/173","26/21081",0.0191247911871205,0.0336485456538613,0.0131041393684879,"SIRT1/EP300",2
"GO:0071425","BP","GO:0071425","hematopoietic stem cell proliferation","2/173","26/21081",0.0191247911871205,0.0336485456538613,0.0131041393684879,"PIM1/ACE",2
"GO:0090023","BP","GO:0090023","positive regulation of neutrophil chemotaxis","2/173","26/21081",0.0191247911871205,0.0336485456538613,0.0131041393684879,"CXCL8/C5AR1",2
"GO:1900273","BP","GO:1900273","positive regulation of long-term synaptic potentiation","2/173","26/21081",0.0191247911871205,0.0336485456538613,0.0131041393684879,"DRD2/APP",2
"GO:1903429","BP","GO:1903429","regulation of cell maturation","2/173","26/21081",0.0191247911871205,0.0336485456538613,0.0131041393684879,"MTOR/LRRK2",2
"GO:1904376","BP","GO:1904376","negative regulation of protein localization to cell periphery","2/173","26/21081",0.0191247911871205,0.0336485456538613,0.0131041393684879,"BCL2L1/CSK",2
"GO:1904385","BP","GO:1904385","cellular response to angiotensin","2/173","26/21081",0.0191247911871205,0.0336485456538613,0.0131041393684879,"AGTR1/SRC",2
"GO:1904754","BP","GO:1904754","positive regulation of vascular associated smooth muscle cell migration","2/173","26/21081",0.0191247911871205,0.0336485456538613,0.0131041393684879,"TERT/MDM2",2
"GO:0002090","BP","GO:0002090","regulation of receptor internalization","3/173","69/21081",0.0191641971454519,0.0336899766946733,0.0131202743342771,"DRD2/DRD3/INSR",3
"GO:0043550","BP","GO:0043550","regulation of lipid kinase activity","3/173","69/21081",0.0191641971454519,0.0336899766946733,0.0131202743342771,"SRC/PTK2/F2",3
"GO:0030004","BP","GO:0030004","cellular monovalent inorganic cation homeostasis","4/173","125/21081",0.0197159580859034,0.0346312963650283,0.0134868632584322,"MAPK3/MAPK1/LRRK2/CFTR",4
"GO:0070498","BP","GO:0070498","interleukin-1-mediated signaling pathway","4/173","125/21081",0.0197159580859034,0.0346312963650283,0.0134868632584322,"MAPK3/IL6/IKBKB/CHUK",4
"GO:0009201","BP","GO:0009201","ribonucleoside triphosphate biosynthetic process","3/173","70/21081",0.0199042841382374,0.0349332107820615,0.0136044412553791,"PARP1/STAT3/VCP",3
"GO:0051148","BP","GO:0051148","negative regulation of muscle cell differentiation","3/173","70/21081",0.0199042841382374,0.0349332107820615,0.0136044412553791,"G6PD/PPARA/HDAC4",3
"GO:0051259","BP","GO:0051259","protein complex oligomerization","6/173","258/21081",0.0199307413936378,0.0349652023871045,0.0136169001133463,"PRMT1/MIF/MIF/SNCA/ACACA/ACACA",6
"GO:1990138","BP","GO:1990138","neuron projection extension","5/173","189/21081",0.0200129790424886,0.0350949847096715,0.0136674427329288,"GSK3B/ABL1/MAPT/MAPT/MAPT",5
"GO:0022037","BP","GO:0022037","metencephalon development","4/173","126/21081",0.0202358113051971,0.0354564792724876,0.0138082237099381,"PTPN11/RORA/ABL1/PSEN1",4
"GO:0031929","BP","GO:0031929","TOR signaling","4/173","126/21081",0.0202358113051971,0.0354564792724876,0.0138082237099381,"MTOR/PIK3CA/AKT1/SIRT1",4
"GO:0001909","BP","GO:0001909","leukocyte mediated cytotoxicity","6/173","259/21081",0.0202693789310044,0.035500655844121,0.0138254278993096,"NOS2/F2/CTSG/STAT5B/ELANE/ELANE",6
"GO:0002068","BP","GO:0002068","glandular epithelial cell development","2/173","27/21081",0.0205448217158299,0.0358353643146803,0.0139557772609475,"GSK3B/FASN",2
"GO:0030220","BP","GO:0030220","platelet formation","2/173","27/21081",0.0205448217158299,0.0358353643146803,0.0139557772609475,"PTPN11/EP300",2
"GO:0032366","BP","GO:0032366","intracellular sterol transport","2/173","27/21081",0.0205448217158299,0.0358353643146803,0.0139557772609475,"CES1/CES1",2
"GO:0032367","BP","GO:0032367","intracellular cholesterol transport","2/173","27/21081",0.0205448217158299,0.0358353643146803,0.0139557772609475,"CES1/CES1",2
"GO:0034698","BP","GO:0034698","response to gonadotropin","2/173","27/21081",0.0205448217158299,0.0358353643146803,0.0139557772609475,"SRD5A1/CCNA2",2
"GO:0044550","BP","GO:0044550","secondary metabolite biosynthetic process","2/173","27/21081",0.0205448217158299,0.0358353643146803,0.0139557772609475,"MC1R/TYR",2
"GO:0048169","BP","GO:0048169","regulation of long-term neuronal synaptic plasticity","2/173","27/21081",0.0205448217158299,0.0358353643146803,0.0139557772609475,"DRD2/APP",2
"GO:0051350","BP","GO:0051350","negative regulation of lyase activity","2/173","27/21081",0.0205448217158299,0.0358353643146803,0.0139557772609475,"DRD2/DRD3",2
"GO:0099563","BP","GO:0099563","modification of synaptic structure","2/173","27/21081",0.0205448217158299,0.0358353643146803,0.0139557772609475,"RHOA/ABL1",2
"GO:1903203","BP","GO:1903203","regulation of oxidative stress-induced neuron death","2/173","27/21081",0.0205448217158299,0.0358353643146803,0.0139557772609475,"PARP1/TLR4",2
"GO:0045089","BP","GO:0045089","positive regulation of innate immune response","7/173","334/21081",0.0206133459572723,0.0359401341700657,0.01399657898833,"SRC/IKBKB/CHUK/TLR4/STAT5B/MMP12/EP300",7
"GO:0010830","BP","GO:0010830","regulation of myotube differentiation","3/173","71/21081",0.0206599742327572,0.0359918944300884,0.0140167365805202,"MTOR/HDAC4/MAPK14",3
"GO:0035773","BP","GO:0035773","insulin secretion involved in cellular response to glucose stimulus","3/173","71/21081",0.0206599742327572,0.0359918944300884,0.0140167365805202,"NR1H4/HMGCR/CFTR",3
"GO:0014902","BP","GO:0014902","myotube differentiation","4/173","127/21081",0.0207640490488895,0.0361435659191854,0.014075803749479,"MTOR/NOS1/HDAC4/MAPK14",4
"GO:0030282","BP","GO:0030282","bone mineralization","4/173","127/21081",0.0207640490488895,0.0361435659191854,0.014075803749479,"ALOX5/ALOX5/PTGS2/MMP13",4
"GO:0032200","BP","GO:0032200","telomere organization","5/173","191/21081",0.0208361438720211,0.036254207744561,0.0141188922655361,"MAPK3/TERT/SRC/MAPK1/PARP1",5
"GO:0006081","BP","GO:0006081","cellular aldehyde metabolic process","3/173","72/21081",0.0214312765742615,0.0372439648932667,0.0145043447528744,"AKR1C1/CYP1B1/GLO1",3
"GO:0045739","BP","GO:0045739","positive regulation of DNA repair","3/173","72/21081",0.0214312765742615,0.0372439648932667,0.0145043447528744,"PARP1/EGFR/SIRT1",3
"GO:1903672","BP","GO:1903672","positive regulation of sprouting angiogenesis","3/173","72/21081",0.0214312765742615,0.0372439648932667,0.0145043447528744,"PTGS2/AGTR1/ABL1",3
"GO:0051260","BP","GO:0051260","protein homooligomerization","5/173","193/21081",0.0216811439025297,0.0376627884063159,0.0146674520010228,"PRMT1/MIF/MIF/ACACA/ACACA",5
"GO:0090398","BP","GO:0090398","cellular senescence","4/173","129/21081",0.0218458048441491,0.0379333162169143,0.014772806751555,"TERT/SIRT1/ABL1/MAPK14",4
"GO:0002026","BP","GO:0002026","regulation of the force of heart contraction","2/173","28/21081",0.0220074917608753,0.0379812479658648,0.0147914733627329,"NOS3/NOS1",2
"GO:0002092","BP","GO:0002092","positive regulation of receptor internalization","2/173","28/21081",0.0220074917608753,0.0379812479658648,0.0147914733627329,"DRD2/INSR",2
"GO:0002693","BP","GO:0002693","positive regulation of cellular extravasation","2/173","28/21081",0.0220074917608753,0.0379812479658648,0.0147914733627329,"ELANE/ELANE",2
"GO:0006706","BP","GO:0006706","steroid catabolic process","2/173","28/21081",0.0220074917608753,0.0379812479658648,0.0147914733627329,"CYP19A1/SRD5A1",2
"GO:0006972","BP","GO:0006972","hyperosmotic response","2/173","28/21081",0.0220074917608753,0.0379812479658648,0.0147914733627329,"AKR1B1/MAPK10",2
"GO:0010884","BP","GO:0010884","positive regulation of lipid storage","2/173","28/21081",0.0220074917608753,0.0379812479658648,0.0147914733627329,"SREBF2/NR1H2",2
"GO:0010934","BP","GO:0010934","macrophage cytokine production","2/173","28/21081",0.0220074917608753,0.0379812479658648,0.0147914733627329,"TLR4/SIRT1",2
"GO:0042403","BP","GO:0042403","thyroid hormone metabolic process","2/173","28/21081",0.0220074917608753,0.0379812479658648,0.0147914733627329,"CTSB/CTSB",2
"GO:0045932","BP","GO:0045932","negative regulation of muscle contraction","2/173","28/21081",0.0220074917608753,0.0379812479658648,0.0147914733627329,"PTGS2/PIK3CG",2
"GO:0048520","BP","GO:0048520","positive regulation of behavior","2/173","28/21081",0.0220074917608753,0.0379812479658648,0.0147914733627329,"MTOR/HDAC4",2
"GO:0050996","BP","GO:0050996","positive regulation of lipid catabolic process","2/173","28/21081",0.0220074917608753,0.0379812479658648,0.0147914733627329,"PPARA/FABP1",2
"GO:0051647","BP","GO:0051647","nucleus localization","2/173","28/21081",0.0220074917608753,0.0379812479658648,0.0147914733627329,"MTOR/PTK2",2
"GO:0072337","BP","GO:0072337","modified amino acid transport","2/173","28/21081",0.0220074917608753,0.0379812479658648,0.0147914733627329,"ABCC1/ABCC1",2
"GO:1903421","BP","GO:1903421","regulation of synaptic vesicle recycling","2/173","28/21081",0.0220074917608753,0.0379812479658648,0.0147914733627329,"LRRK2/SNCA",2
"GO:1904353","BP","GO:1904353","regulation of telomere capping","2/173","28/21081",0.0220074917608753,0.0379812479658648,0.0147914733627329,"MAPK3/MAPK1",2
"GO:0002832","BP","GO:0002832","negative regulation of response to biotic stimulus","5/173","194/21081",0.0221118928275295,0.0381304515520182,0.0148495794279205,"NR1H3/DRD2/PPARG/NR1H2/MMP12",5
"GO:2001257","BP","GO:2001257","regulation of cation channel activity","5/173","194/21081",0.0221118928275295,0.0381304515520182,0.0148495794279205,"DRD2/DRD3/NOS1/MMP9/APP",5
"GO:0002720","BP","GO:0002720","positive regulation of cytokine production involved in immune response","4/173","130/21081",0.0223993835155771,0.0385948826267994,0.0150304481523401,"IL6/TLR4/MIF/MIF",4
"GO:0050853","BP","GO:0050853","B cell receptor signaling pathway","4/173","130/21081",0.0223993835155771,0.0385948826267994,0.0150304481523401,"PRKCB/MAPK1/ABL1/CD38",4
"GO:0002218","BP","GO:0002218","activation of innate immune response","5/173","195/21081",0.0225481725768452,0.038835502747878,0.0151241556080475,"SRC/IKBKB/CHUK/TLR4/EP300",5
"GO:0001654","BP","GO:0001654","eye development","8/173","419/21081",0.0226467614902623,0.0389895014473762,0.0151841290892657,"SLC6A3/SLC6A3/DRD2/CDK4/EGFR/STAT3/CYP1B1/PSEN1",8
"GO:1901292","BP","GO:1901292","nucleoside phosphate catabolic process","3/173","74/21081",0.0230207361394993,0.0396172976333464,0.0154286189641205,"PDE4A/XDH/VCP",3
"GO:0010469","BP","GO:0010469","regulation of signaling receptor activity","5/173","197/21081",0.0234374167019138,0.0402995358241314,0.0156943108138223,"ESR2/SERPINE1/SRC/APP/PSEN1",5
"GO:0031954","BP","GO:0031954","positive regulation of protein autophosphorylation","2/173","29/21081",0.0235120144288119,0.0402995358241314,0.0156943108138223,"SRC/ACE",2
"GO:0036296","BP","GO:0036296","response to increased oxygen levels","2/173","29/21081",0.0235120144288119,0.0402995358241314,0.0156943108138223,"PPARG/CDK4",2
"GO:0036344","BP","GO:0036344","platelet morphogenesis","2/173","29/21081",0.0235120144288119,0.0402995358241314,0.0156943108138223,"PTPN11/EP300",2
"GO:0044030","BP","GO:0044030","regulation of DNA methylation","2/173","29/21081",0.0235120144288119,0.0402995358241314,0.0156943108138223,"PIK3CA/PARP1",2
"GO:0045822","BP","GO:0045822","negative regulation of heart contraction","2/173","29/21081",0.0235120144288119,0.0402995358241314,0.0156943108138223,"PIK3CG/IL2",2
"GO:0048668","BP","GO:0048668","collateral sprouting","2/173","29/21081",0.0235120144288119,0.0402995358241314,0.0156943108138223,"ABL1/APP",2
"GO:0048873","BP","GO:0048873","homeostasis of number of cells within a tissue","2/173","29/21081",0.0235120144288119,0.0402995358241314,0.0156943108138223,"PTPN11/NOS3",2
"GO:0051590","BP","GO:0051590","positive regulation of neurotransmitter transport","2/173","29/21081",0.0235120144288119,0.0402995358241314,0.0156943108138223,"DRD2/CNR1",2
"GO:0071624","BP","GO:0071624","positive regulation of granulocyte chemotaxis","2/173","29/21081",0.0235120144288119,0.0402995358241314,0.0156943108138223,"CXCL8/C5AR1",2
"GO:0030968","BP","GO:0030968","endoplasmic reticulum unfolded protein response","4/173","132/21081",0.0235320857438111,0.0403176743247795,0.0157013746983324,"CCND1/CXCL8/VCP/EP300",4
"GO:0150063","BP","GO:0150063","visual system development","8/173","423/21081",0.0237975461347721,0.0407560554319414,0.0158720984848477,"SLC6A3/SLC6A3/DRD2/CDK4/EGFR/STAT3/CYP1B1/PSEN1",8
"GO:0043967","BP","GO:0043967","histone H4 acetylation","3/173","75/21081",0.0238388934508174,0.0407939823892562,0.015886868815179,"SIRT1/OGT/EP300",3
"GO:0050771","BP","GO:0050771","negative regulation of axonogenesis","3/173","75/21081",0.0238388934508174,0.0407939823892562,0.015886868815179,"PTK2/RHOA/PSEN1",3
"GO:0051928","BP","GO:0051928","positive regulation of calcium ion transport","4/173","134/21081",0.02469902622299,0.0422488576576025,0.0164534575907027,"G6PD/SNCA/F2/ABL1",4
"GO:0007176","BP","GO:0007176","regulation of epidermal growth factor-activated receptor activity","2/173","30/21081",0.025057612738179,0.0427417890503905,0.0166454255211044,"APP/PSEN1",2
"GO:0031063","BP","GO:0031063","regulation of histone deacetylation","2/173","30/21081",0.025057612738179,0.0427417890503905,0.0166454255211044,"MAPK8/LRRK2",2
"GO:0032647","BP","GO:0032647","regulation of interferon-alpha production","2/173","30/21081",0.025057612738179,0.0427417890503905,0.0166454255211044,"CHUK/TLR4",2
"GO:0036475","BP","GO:0036475","neuron death in response to oxidative stress","2/173","30/21081",0.025057612738179,0.0427417890503905,0.0166454255211044,"PARP1/TLR4",2
"GO:0038111","BP","GO:0038111","interleukin-7-mediated signaling pathway","2/173","30/21081",0.025057612738179,0.0427417890503905,0.0166454255211044,"STAT5B/STAT3",2
"GO:0045686","BP","GO:0045686","negative regulation of glial cell differentiation","2/173","30/21081",0.025057612738179,0.0427417890503905,0.0166454255211044,"DRD3/F2",2
"GO:0048265","BP","GO:0048265","response to pain","2/173","30/21081",0.025057612738179,0.0427417890503905,0.0166454255211044,"TACR1/CACNA1B",2
"GO:0055001","BP","GO:0055001","muscle cell development","5/173","201/21081",0.0252832650033562,0.0431093872388685,0.0167885835031156,"G6PD/PPARA/MTOR/HDAC4/CDK1",5
"GO:0045333","BP","GO:0045333","cellular respiration","5/173","203/21081",0.0262402091090262,0.0447230840370045,0.0174170239700167,"NOS2/PIK3CA/SNCA/CDK1/VCP",5
"GO:2000401","BP","GO:2000401","regulation of lymphocyte migration","3/173","78/21081",0.0263870031600904,0.0449552431544604,0.0175074363599638,"AKT1/RHOA/APP",3
"GO:0006997","BP","GO:0006997","nucleus organization","4/173","137/21081",0.0265140640882483,0.0451208905555156,0.0175719463287388,"PRKCB/PRKCA/CDK1/PPP2CA",4
"GO:0042476","BP","GO:0042476","odontogenesis","4/173","137/21081",0.0265140640882483,0.0451208905555156,0.0175719463287388,"PPARA/SERPINE1/SRC/RHOA",4
"GO:0032412","BP","GO:0032412","regulation of ion transmembrane transporter activity","6/173","276/21081",0.0266369021469955,0.0451208905555156,0.0175719463287388,"DRD2/DRD3/NOS1/MMP9/APP/CFTR",6
"GO:0009435","BP","GO:0009435","NAD biosynthetic process","2/173","31/21081",0.0266435195113647,0.0451208905555156,0.0175719463287388,"IDO1/PTGS2",2
"GO:0010800","BP","GO:0010800","positive regulation of peptidyl-threonine phosphorylation","2/173","31/21081",0.0266435195113647,0.0451208905555156,0.0175719463287388,"MAPK1/APP",2
"GO:0015721","BP","GO:0015721","bile acid and bile salt transport","2/173","31/21081",0.0266435195113647,0.0451208905555156,0.0175719463287388,"NR1H4/AKR1C1",2
"GO:0018195","BP","GO:0018195","peptidyl-arginine modification","2/173","31/21081",0.0266435195113647,0.0451208905555156,0.0175719463287388,"NR1H4/PRMT1",2
"GO:0019048","BP","GO:0019048","modulation by virus of host process","2/173","31/21081",0.0266435195113647,0.0451208905555156,0.0175719463287388,"BCL2L1/INSR",2
"GO:0036151","BP","GO:0036151","phosphatidylcholine acyl-chain remodeling","2/173","31/21081",0.0266435195113647,0.0451208905555156,0.0175719463287388,"NR1H3/NR1H2",2
"GO:0043032","BP","GO:0043032","positive regulation of macrophage activation","2/173","31/21081",0.0266435195113647,0.0451208905555156,0.0175719463287388,"TLR4/LRRK2",2
"GO:0050974","BP","GO:0050974","detection of mechanical stimulus involved in sensory perception","2/173","31/21081",0.0266435195113647,0.0451208905555156,0.0175719463287388,"BACE1/HTR2A",2
"GO:0060444","BP","GO:0060444","branching involved in mammary gland duct morphogenesis","2/173","31/21081",0.0266435195113647,0.0451208905555156,0.0175719463287388,"ESR1/SRC",2
"GO:1902624","BP","GO:1902624","positive regulation of neutrophil migration","2/173","31/21081",0.0266435195113647,0.0451208905555156,0.0175719463287388,"CXCL8/C5AR1",2
"GO:1904357","BP","GO:1904357","negative regulation of telomere maintenance via telomere lengthening","2/173","31/21081",0.0266435195113647,0.0451208905555156,0.0175719463287388,"SRC/PARP1",2
"GO:1904837","BP","GO:1904837","beta-catenin-TCF complex assembly","2/173","31/21081",0.0266435195113647,0.0451208905555156,0.0175719463287388,"TERT/EP300",2
"GO:0045619","BP","GO:0045619","regulation of lymphocyte differentiation","5/173","204/21081",0.0267272571539258,0.0452446675884584,0.0176201502394512,"ERBB2/RHOA/STAT5B/ABL1/IL2",5
"GO:0009063","BP","GO:0009063","cellular amino acid catabolic process","4/173","138/21081",0.0271364003977499,0.0459007027428501,0.0178756375399191,"NOS2/IDO1/NOS3/NOS1",4
"GO:1990266","BP","GO:1990266","neutrophil migration","4/173","138/21081",0.0271364003977499,0.0459007027428501,0.0178756375399191,"PIK3CG/CXCL8/DPP4/C5AR1",4
"GO:0007422","BP","GO:0007422","peripheral nervous system development","3/173","79/21081",0.0272675460243119,0.0461041794895747,0.0179548798250019,"ERBB2/AKT1/CDK1",3
"GO:0048880","BP","GO:0048880","sensory system development","8/173","436/21081",0.0278212958384736,0.0470217525925515,0.0183122208508481,"SLC6A3/SLC6A3/DRD2/CDK4/EGFR/STAT3/CYP1B1/PSEN1",8
"GO:0019731","BP","GO:0019731","antibacterial humoral response","3/173","80/21081",0.0281636474759049,0.0475625350258823,0.018522823961226,"CTSG/ELANE/ELANE",3
"GO:0035924","BP","GO:0035924","cellular response to vascular endothelial growth factor stimulus","3/173","80/21081",0.0281636474759049,0.0475625350258823,0.018522823961226,"AKT1/XDH/MAPK14",3
"GO:0006575","BP","GO:0006575","cellular modified amino acid metabolic process","5/173","207/21081",0.0282229358208117,0.0475702512514314,0.0185258289795123,"G6PD/GSR/CTSB/CTSB/GLO1",5
"GO:0002828","BP","GO:0002828","regulation of type 2 immune response","2/173","32/21081",0.0282689772675605,0.0475702512514314,0.0185258289795123,"IDO1/IL6",2
"GO:0006356","BP","GO:0006356","regulation of transcription by RNA polymerase I","2/173","32/21081",0.0282689772675605,0.0475702512514314,0.0185258289795123,"ERBB2/MTOR",2
"GO:0032607","BP","GO:0032607","interferon-alpha production","2/173","32/21081",0.0282689772675605,0.0475702512514314,0.0185258289795123,"CHUK/TLR4",2
"GO:0035066","BP","GO:0035066","positive regulation of histone acetylation","2/173","32/21081",0.0282689772675605,0.0475702512514314,0.0185258289795123,"MAPK3/NOS1",2
"GO:0045987","BP","GO:0045987","positive regulation of smooth muscle contraction","2/173","32/21081",0.0282689772675605,0.0475702512514314,0.0185258289795123,"PTGS2/RHOA",2
"GO:0050849","BP","GO:0050849","negative regulation of calcium-mediated signaling","2/173","32/21081",0.0282689772675605,0.0475702512514314,0.0185258289795123,"GSK3B/MTOR",2
"GO:1903792","BP","GO:1903792","negative regulation of anion transport","2/173","32/21081",0.0282689772675605,0.0475702512514314,0.0185258289795123,"MTOR/AKT1",2
"GO:2000108","BP","GO:2000108","positive regulation of leukocyte apoptotic process","2/173","32/21081",0.0282689772675605,0.0475702512514314,0.0185258289795123,"IDO1/SIRT1",2
"GO:0051216","BP","GO:0051216","cartilage development","5/173","208/21081",0.0287330684150924,0.0483320695549199,0.0188225126259638,"MAPK3/PTPN11/MAPK14/ESRRA/MMP13",5
"GO:0009142","BP","GO:0009142","nucleoside triphosphate biosynthetic process","3/173","81/21081",0.0290752860834991,0.0487918209197424,0.0190015588772182,"PARP1/STAT3/VCP",3
"GO:0033866","BP","GO:0033866","nucleoside bisphosphate biosynthetic process","3/173","81/21081",0.0290752860834991,0.0487918209197424,0.0190015588772182,"FASN/ACACA/ACACA",3
"GO:0034030","BP","GO:0034030","ribonucleoside bisphosphate biosynthetic process","3/173","81/21081",0.0290752860834991,0.0487918209197424,0.0190015588772182,"FASN/ACACA/ACACA",3
"GO:0034033","BP","GO:0034033","purine nucleoside bisphosphate biosynthetic process","3/173","81/21081",0.0290752860834991,0.0487918209197424,0.0190015588772182,"FASN/ACACA/ACACA",3
"GO:0042446","BP","GO:0042446","hormone biosynthetic process","3/173","81/21081",0.0290752860834991,0.0487918209197424,0.0190015588772182,"CYP19A1/SRD5A1/AKR1B1",3
"GO:0070373","BP","GO:0070373","negative regulation of ERK1 and ERK2 cascade","3/173","81/21081",0.0290752860834991,0.0487918209197424,0.0190015588772182,"CSK/TLR4/ABL1",3
"GO:0018205","BP","GO:0018205","peptidyl-lysine modification","8/173","440/21081",0.0291490035406624,0.048896216361735,0.0190422147924954,"MAPK3/MDM2/NOS1/HDAC4/SNCA/SIRT1/OGT/EP300",8
"GO:1903322","BP","GO:1903322","positive regulation of protein modification by small protein conjugation or removal","4/173","142/21081",0.0297128916593808,0.0498224454067518,0.0194029268012074,"XIAP/LRRK2/HDAC4/VCP",4
"GO:0033688","BP","GO:0033688","regulation of osteoblast proliferation","2/173","33/21081",0.0299332381167976,0.0499946260842268,0.0194699810988108,"RHOA/ABL1",2
"GO:0042104","BP","GO:0042104","positive regulation of activated T cell proliferation","2/173","33/21081",0.0299332381167976,0.0499946260842268,0.0194699810988108,"STAT5B/IL2",2
"GO:0042738","BP","GO:0042738","exogenous drug catabolic process","2/173","33/21081",0.0299332381167976,0.0499946260842268,0.0194699810988108,"NR1I2/NOS1",2
"GO:0042744","BP","GO:0042744","hydrogen peroxide catabolic process","2/173","33/21081",0.0299332381167976,0.0499946260842268,0.0194699810988108,"SNCA/MPO",2
"GO:0043552","BP","GO:0043552","positive regulation of phosphatidylinositol 3-kinase activity","2/173","33/21081",0.0299332381167976,0.0499946260842268,0.0194699810988108,"SRC/PTK2",2
"GO:0048710","BP","GO:0048710","regulation of astrocyte differentiation","2/173","33/21081",0.0299332381167976,0.0499946260842268,0.0194699810988108,"IL6/F2",2
"GO:0051968","BP","GO:0051968","positive regulation of synaptic transmission, glutamatergic","2/173","33/21081",0.0299332381167976,0.0499946260842268,0.0194699810988108,"PTGS2/EGFR",2
"GO:0071353","BP","GO:0071353","cellular response to interleukin-4","2/173","33/21081",0.0299332381167976,0.0499946260842268,0.0194699810988108,"CDK4/FASN",2
"GO:0071549","BP","GO:0071549","cellular response to dexamethasone stimulus","2/173","33/21081",0.0299332381167976,0.0499946260842268,0.0194699810988108,"SRD5A1/EGFR",2
"GO:1905476","BP","GO:1905476","negative regulation of protein localization to membrane","2/173","33/21081",0.0299332381167976,0.0499946260842268,0.0194699810988108,"BCL2L1/CSK",2
"GO:0045121","CC","GO:0045121","membrane raft","37/173","366/21872",2.87408595179968e-30,5.17800182407097e-28,3.126530000327e-28,"SLC22A6/CTSD/MAPK3/SLC6A3/SLC6A3/BACE1/LDHB/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CNR1/PTGS2/SRC/HTR2A/IKBKB/CSK/MAPK1/NOS3/CHRNA3/NOS1/LRRK2/EGFR/INSR/ABCG2/APP/DPP4/MAPT/MAPT/MAPT/PSEN2/PPP2CA/PSEN1",37
"GO:0098857","CC","GO:0098857","membrane microdomain","37/173","367/21872",3.17668823562636e-30,5.17800182407097e-28,3.126530000327e-28,"SLC22A6/CTSD/MAPK3/SLC6A3/SLC6A3/BACE1/LDHB/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CNR1/PTGS2/SRC/HTR2A/IKBKB/CSK/MAPK1/NOS3/CHRNA3/NOS1/LRRK2/EGFR/INSR/ABCG2/APP/DPP4/MAPT/MAPT/MAPT/PSEN2/PPP2CA/PSEN1",37
"GO:0098589","CC","GO:0098589","membrane region","37/173","381/21872",1.2504184990885e-29,1.35878810234284e-27,8.20450032735263e-28,"SLC22A6/CTSD/MAPK3/SLC6A3/SLC6A3/BACE1/LDHB/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CNR1/PTGS2/SRC/HTR2A/IKBKB/CSK/MAPK1/NOS3/CHRNA3/NOS1/LRRK2/EGFR/INSR/ABCG2/APP/DPP4/MAPT/MAPT/MAPT/PSEN2/PPP2CA/PSEN1",37
"GO:0101002","CC","GO:0101002","ficolin-1-rich granule","16/173","146/21872",4.14472681796785e-14,2.70236188531504e-12,1.63171350517892e-12,"CTSD/ALOX5/ALOX5/MAPK1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/MIF/MIF/CTSB/CTSB/MMP9/MAPK14/VCP",16
"GO:1904813","CC","GO:1904813","ficolin-1-rich granule lumen","16/173","146/21872",4.14472681796785e-14,2.70236188531504e-12,1.63171350517892e-12,"CTSD/ALOX5/ALOX5/MAPK1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/MIF/MIF/CTSB/CTSB/MMP9/MAPK14/VCP",16
"GO:0005901","CC","GO:0005901","caveola","12/173","92/21872",8.55859912048197e-12,4.6501721887952e-10,2.80782111496514e-10,"SLC22A6/MAPK3/SLC6A3/SLC6A3/PTGS2/SRC/HTR2A/MAPK1/NOS3/NOS1/LRRK2/INSR",12
"GO:0001891","CC","GO:0001891","phagocytic cup","9/173","39/21872",1.69895795932301e-11,7.91228992484717e-10,4.77752087809629e-10,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TLR4",9
"GO:0044853","CC","GO:0044853","plasma membrane raft","13/173","127/21872",2.62026950564447e-11,1.06775982355012e-09,6.4472420730989e-10,"SLC22A6/MAPK3/SLC6A3/SLC6A3/PTGS2/SRC/HTR2A/MAPK1/NOS3/CHRNA3/NOS1/LRRK2/INSR",13
"GO:0031983","CC","GO:0031983","vesicle lumen","19/173","381/21872",2.07195875537268e-10,7.50509504723881e-09,4.531652482511e-09,"FABP5/PLG/CTSD/ALOX5/ALOX5/BACE1/TTR/SERPINE1/MAPK1/EGFR/MIF/MIF/MPO/CTSG/MAPK14/APP/VCP/ELANE/ELANE",19
"GO:0016234","CC","GO:0016234","inclusion body","11/173","97/21872",3.04130400615329e-10,9.91465106005972e-09,5.98656683316489e-09,"LRRK2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SNCA/MAPT/MAPT/MAPT/PSEN1",11
"GO:0060205","CC","GO:0060205","cytoplasmic vesicle lumen","18/173","379/21872",1.38621273127667e-09,4.10823045814722e-08,2.4805912033372e-08,"FABP5/PLG/CTSD/ALOX5/ALOX5/BACE1/TTR/SERPINE1/MAPK1/MIF/MIF/MPO/CTSG/MAPK14/APP/VCP/ELANE/ELANE",18
"GO:0034774","CC","GO:0034774","secretory granule lumen","17/173","375/21872",8.14042540874946e-09,2.2114822360436e-07,1.33531539599662e-07,"FABP5/PLG/CTSD/ALOX5/ALOX5/TTR/SERPINE1/MAPK1/MIF/MIF/MPO/CTSG/MAPK14/APP/VCP/ELANE/ELANE",17
"GO:0045177","CC","GO:0045177","apical part of cell","18/173","472/21872",4.15052730089649e-08,1.0408245385325e-06,6.28460409123598e-07,"NPC1L1/FABP1/DRD3/ERBB2/EGFR/PTK2/CTSB/CTSB/NOX4/ABCC1/ABCC1/ABCG2/APP/CFTR/DPP4/PSEN2/C5AR1/PSEN1",18
"GO:1902911","CC","GO:1902911","protein kinase complex","9/173","122/21872",5.57967744273627e-07,1.22787609289615e-05,7.41404034134903e-06,"IGF1R/CDK2/IKBKB/CDK4/CCNA2/CHUK/CCND1/INSR/CDK1",9
"GO:0098978","CC","GO:0098978","glutamatergic synapse","15/173","392/21872",5.64973662375528e-07,1.22787609289615e-05,7.41404034134903e-06,"PLG/DRD2/CNR1/DRD3/SRC/GSK3B/HTR2A/MTOR/LRRK2/PPP1CA/RHOA/MAPK10/STAT3/MAPK14/VCP",15
"GO:0005775","CC","GO:0005775","vacuolar lumen","11/173","206/21872",7.88054151256941e-07,1.60566033318602e-05,9.69513988717421e-06,"FABP5/CTSD/TTR/MAPK1/CTSB/CTSB/MPO/CTSG/VCP/ELANE/ELANE",11
"GO:0035578","CC","GO:0035578","azurophil granule lumen","8/173","106/21872",2.03271589476863e-06,3.8980316570269e-05,2.35367103604788e-05,"FABP5/TTR/MAPK1/MPO/CTSG/VCP/ELANE/ELANE",8
"GO:0099056","CC","GO:0099056","integral component of presynaptic membrane","7/173","76/21872",2.36894198017689e-06,4.29041714187593e-05,2.59059737013496e-05,"SLC6A3/SLC6A3/DRD2/CNR1/HTR2A/PSEN2/PSEN1",7
"GO:0061695","CC","GO:0061695","transferase complex, transferring phosphorus-containing groups","12/173","285/21872",2.99927716397588e-06,5.14612818661124e-05,3.10728437486697e-05,"IGF1R/TERT/CDK2/IKBKB/PIK3CA/PIK3CG/CDK4/CCNA2/CHUK/CCND1/INSR/CDK1",12
"GO:0016324","CC","GO:0016324","apical plasma membrane","14/173","399/21872",3.74525241167878e-06,6.10476143103642e-05,3.68611684728385e-05,"NPC1L1/ERBB2/EGFR/PTK2/CTSB/CTSB/NOX4/ABCC1/ABCC1/ABCG2/CFTR/DPP4/PSEN2/PSEN1",14
"GO:0055037","CC","GO:0055037","recycling endosome","11/173","246/21872",4.42235465271213e-06,6.8651791275436e-05,4.14526476219132e-05,"BACE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/APP/CFTR",11
"GO:0016235","CC","GO:0016235","aggresome","6/173","55/21872",4.72058864799559e-06,6.99505408748437e-05,4.22368457978552e-05,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/PSEN1",6
"GO:0098889","CC","GO:0098889","intrinsic component of presynaptic membrane","7/173","85/21872",5.03861922654483e-06,7.14169507762442e-05,4.31222789640221e-05,"SLC6A3/SLC6A3/DRD2/CNR1/HTR2A/PSEN2/PSEN1",7
"GO:0005766","CC","GO:0005766","primary lysosome","9/173","172/21872",9.58306797268565e-06,0.000124963206363821,7.54540509849355e-05,"FABP5/TTR/MAPK1/MPO/CTSG/VCP/ELANE/ELANE/PSEN1",9
"GO:0042582","CC","GO:0042582","azurophil granule","9/173","172/21872",9.58306797268565e-06,0.000124963206363821,7.54540509849355e-05,"FABP5/TTR/MAPK1/MPO/CTSG/VCP/ELANE/ELANE/PSEN1",9
"GO:0150034","CC","GO:0150034","distal axon","12/173","322/21872",1.03644784941517e-05,0.000125268822536738,7.56385851287377e-05,"DRD2/CNR1/PRKCB/NOS1/LRRK2/SNCA/APP/MAPT/MAPT/MAPT/PSEN2/PSEN1",12
"GO:0097386","CC","GO:0097386","glial cell projection","5/173","37/21872",1.03750251794231e-05,0.000125268822536738,7.56385851287377e-05,"AKR1B1/APP/MAPT/MAPT/MAPT",5
"GO:0043197","CC","GO:0043197","dendritic spine","9/173","189/21872",2.03531583518094e-05,0.000236968915096066,0.000143084233525878,"DRD2/NOS1/PTK2/PPP1CA/RHOA/APP/MAPT/MAPT/MAPT",9
"GO:0044309","CC","GO:0044309","neuron spine","9/173","191/21872",2.21218947847023e-05,0.000247159232777837,0.000149237250660173,"DRD2/NOS1/PTK2/PPP1CA/RHOA/APP/MAPT/MAPT/MAPT",9
"GO:1902554","CC","GO:1902554","serine/threonine protein kinase complex","7/173","107/21872",2.30099192521677e-05,0.000247159232777837,0.000149237250660173,"CDK2/IKBKB/CDK4/CCNA2/CHUK/CCND1/CDK1",7
"GO:0000307","CC","GO:0000307","cyclin-dependent protein kinase holoenzyme complex","5/173","44/21872",2.47180850890189e-05,0.000247159232777837,0.000149237250660173,"CDK2/CDK4/CCNA2/CCND1/CDK1",5
"GO:0098691","CC","GO:0098691","dopaminergic synapse","4/173","22/21872",2.47406144552877e-05,0.000247159232777837,0.000149237250660173,"SLC6A3/SLC6A3/DRD2/DRD3",4
"GO:0030426","CC","GO:0030426","growth cone","9/173","194/21872",2.50191861400878e-05,0.000247159232777837,0.000149237250660173,"CNR1/LRRK2/SNCA/APP/MAPT/MAPT/MAPT/PSEN2/PSEN1",9
"GO:0030427","CC","GO:0030427","site of polarized growth","9/173","202/21872",3.43659562618554e-05,0.000329508874746025,0.000198960799410742,"CNR1/LRRK2/SNCA/APP/MAPT/MAPT/MAPT/PSEN2/PSEN1",9
"GO:0099699","CC","GO:0099699","integral component of synaptic membrane","8/173","166/21872",5.43729604848004e-05,0.000506445289086998,0.000305796800320532,"SLC6A3/SLC6A3/DRD2/CNR1/DRD3/HTR2A/PSEN2/PSEN1",8
"GO:0031252","CC","GO:0031252","cell leading edge","13/173","449/21872",6.21830586375031e-05,0.000563102142106278,0.00034000678260857,"PDE4A/SRC/PIK3CA/TLR4/INSR/PTK2/RHOA/ABL1/APP/DPP4/MAPT/MAPT/MAPT",13
"GO:0008180","CC","GO:0008180","COP9 signalosome","5/173","55/21872",7.38119994377716e-05,0.000650343562613879,0.000392684036838216,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",5
"GO:0031965","CC","GO:0031965","nuclear membrane","11/173","339/21872",8.52393975287881e-05,0.000731264305115393,0.000441544801603418,"ALOX5/ALOX5/BCL2L1/PTGS2/CDK4/EGFR/CCND1/SIRT1/ABL1/PSEN2/PSEN1",11
"GO:0099240","CC","GO:0099240","intrinsic component of synaptic membrane","8/173","178/21872",8.87545608498027e-05,0.00074189709838553,0.000447964989984159,"SLC6A3/SLC6A3/DRD2/CNR1/DRD3/HTR2A/PSEN2/PSEN1",8
"GO:0035253","CC","GO:0035253","ciliary rootlet","3/173","12/21872",0.000101523189894595,0.000827413997640948,0.000499600960797085,"APP/PSEN2/PSEN1",3
"GO:0005925","CC","GO:0005925","focal adhesion","13/173","475/21872",0.000109327313671516,0.000869285469680833,0.000524883380143093,"MAPK3/SRC/MAPK1/EGFR/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/PTK2/RHOA/NOX4/DPP4",13
"GO:0031256","CC","GO:0031256","leading edge membrane","8/173","187/21872",0.000124991643199074,0.000970173230545194,0.000585800433038267,"PDE4A/SRC/INSR/RHOA/DPP4/MAPT/MAPT/MAPT",8
"GO:0030055","CC","GO:0030055","cell-substrate junction","13/173","483/21872",0.000128988374238789,0.000977911860508031,0.00059047309627059,"MAPK3/SRC/MAPK1/EGFR/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/PTK2/RHOA/NOX4/DPP4",13
"GO:0098562","CC","GO:0098562","cytoplasmic side of membrane","8/173","200/21872",0.00019820176571187,0.00146849490050158,0.00088669210976363,"G6PD/ACP1/SRC/IKBKB/CHUK/LRRK2/PTK2/RHOA",8
"GO:0031253","CC","GO:0031253","cell projection membrane","11/173","380/21872",0.000230739340484867,0.00167157833329037,0.00100931594551275,"NPC1L1/DRD2/PDE4A/SRC/INSR/RHOA/ABCG2/DPP4/MAPT/MAPT/MAPT",11
"GO:0005667","CC","GO:0005667","transcription regulator complex","12/173","451/21872",0.00026076775801222,0.00184804976330399,0.00111587118417128,"NR1H3/PPARG/CDK2/CSNK2A1/CDK4/PARP1/HDAC4/CCND1/STAT3/ELANE/ELANE/EP300",12
"GO:0043198","CC","GO:0043198","dendritic shaft","4/173","42/21872",0.000334666164246681,0.00232130147966847,0.0014016253687375,"HTR2A/APP/PSEN2/PSEN1",4
"GO:0005641","CC","GO:0005641","nuclear envelope lumen","3/173","18/21872",0.000363629443375921,0.00241924894980714,0.00146076704428136,"ALOX5/ALOX5/APP",3
"GO:0030673","CC","GO:0030673","axolemma","3/173","18/21872",0.000363629443375921,0.00241924894980714,0.00146076704428136,"MAPT/MAPT/MAPT",3
"GO:0042734","CC","GO:0042734","presynaptic membrane","7/173","168/21872",0.000389557407573891,0.00253991429738177,0.00153362600455405,"SLC6A3/SLC6A3/DRD2/CNR1/HTR2A/PSEN2/PSEN1",7
"GO:0017053","CC","GO:0017053","transcription repressor complex","5/173","79/21872",0.000410483615795972,0.00262387566175465,0.00158432272763358,"CSNK2A1/HDAC4/CCND1/ELANE/ELANE",5
"GO:0009898","CC","GO:0009898","cytoplasmic side of plasma membrane","7/173","172/21872",0.000448713979866249,0.00281309148916148,0.00169857316265159,"G6PD/ACP1/SRC/IKBKB/CHUK/PTK2/RHOA",7
"GO:0031968","CC","GO:0031968","organelle outer membrane","8/173","227/21872",0.000463931038821738,0.00285361355954503,0.00172304079959613,"BCL2L1/CNR1/PTGS2/MTOR/MAOA/LRRK2/MAOB/PSEN1",8
"GO:0019867","CC","GO:0019867","outer membrane","8/173","229/21872",0.000491626028324649,0.00296796454136733,0.0017920870818072,"BCL2L1/CNR1/PTGS2/MTOR/MAOA/LRRK2/MAOB/PSEN1",8
"GO:0072562","CC","GO:0072562","blood microparticle","7/173","182/21872",0.000628342744040424,0.00372435881013052,0.00224880561024994,"PLG/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/F2",7
"GO:0120111","CC","GO:0120111","neuron projection cytoplasm","5/173","91/21872",0.000784923880024624,0.00456937830157192,0.0027590369467031,"MAPK1/LRRK2/MAPT/MAPT/MAPT",5
"GO:0099522","CC","GO:0099522","region of cytosol","3/173","26/21872",0.00110601852625734,0.00632564981684021,0.00381949149418508,"PRKCB/MTOR/LRRK2",3
"GO:0062023","CC","GO:0062023","collagen-containing extracellular matrix","11/173","460/21872",0.00112691871641997,0.00633406037160191,0.0038245698724235,"PLG/CTSD/SERPINE1/F2/CTSB/CTSB/MMP9/CTSG/MMP2/ELANE/ELANE",11
"GO:0009925","CC","GO:0009925","basal plasma membrane","4/173","60/21872",0.00130557004623141,0.00721382771307524,0.00435578231302896,"ERBB2/EGFR/ABCC1/ABCC1",4
"GO:0032809","CC","GO:0032809","neuronal cell body membrane","3/173","29/21872",0.00152758557838121,0.00829988164253793,0.00501155268696995,"SLC6A3/SLC6A3/INSR",3
"GO:0016607","CC","GO:0016607","nuclear speck","11/173","482/21872",0.00163287254267853,0.00872649916251148,0.00526914867093848,"TERT/HDAC4/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/MAPK14/MAPT/MAPT/MAPT",11
"GO:0032589","CC","GO:0032589","neuron projection membrane","4/173","64/21872",0.00165999597327094,0.00872836592397303,0.00527027584043576,"INSR/MAPT/MAPT/MAPT",4
"GO:0008021","CC","GO:0008021","synaptic vesicle","7/173","218/21872",0.00178963168121606,0.00926063377899103,0.0055916645678764,"BACE1/BCL2L1/DRD2/LRRK2/APP/PSEN2/PSEN1",7
"GO:0044298","CC","GO:0044298","cell body membrane","3/173","32/21872",0.00203786350558986,0.0103803672315983,0.00626777097936355,"SLC6A3/SLC6A3/INSR",3
"GO:0043204","CC","GO:0043204","perikaryon","6/173","170/21872",0.0023667609056403,0.0118702162344421,0.0071673569126273,"DRD2/MAPK1/LRRK2/PPP1CA/MAPK10/APP",6
"GO:0044304","CC","GO:0044304","main axon","4/173","73/21872",0.00269153561734599,0.0132258677386577,0.00798591303561182,"APP/MAPT/MAPT/MAPT",4
"GO:0030139","CC","GO:0030139","endocytic vesicle","10/173","440/21872",0.00271819981131921,0.0132258677386577,0.00798591303561182,"DRD2/MDM2/DRD3/MTOR/NOS3/EGFR/MPO/DPP4/ELANE/ELANE",10
"GO:0070382","CC","GO:0070382","exocytic vesicle","7/173","237/21872",0.00285911578989862,0.0137069374633375,0.00827638781286443,"BACE1/BCL2L1/DRD2/LRRK2/APP/PSEN2/PSEN1",7
"GO:0042470","CC","GO:0042470","melanosome","5/173","124/21872",0.00308499733173848,0.014240326047147,0.00859845324771229,"CTSD/CTSB/CTSB/TYR/FASN",5
"GO:0048770","CC","GO:0048770","pigment granule","5/173","124/21872",0.00308499733173848,0.014240326047147,0.00859845324771229,"CTSD/CTSB/CTSB/TYR/FASN",5
"GO:0031904","CC","GO:0031904","endosome lumen","3/173","37/21872",0.00310142070351975,0.014240326047147,0.00859845324771229,"CTSB/CTSB/APP",3
"GO:0045178","CC","GO:0045178","basal part of cell","4/173","78/21872",0.00342142684204429,0.0154914604237005,0.00935390086933161,"ERBB2/EGFR/ABCC1/ABCC1",4
"GO:0031594","CC","GO:0031594","neuromuscular junction","4/173","79/21872",0.00358201048077753,0.0159963755716914,0.00965877375494446,"HDAC4/APP/PSEN2/PSEN1",4
"GO:0099055","CC","GO:0099055","integral component of postsynaptic membrane","5/173","129/21872",0.00365437163318357,0.0160989885461871,0.00972073250932187,"SLC6A3/SLC6A3/DRD2/DRD3/HTR2A",5
"GO:0098687","CC","GO:0098687","chromosomal region","9/173","388/21872",0.00384227375746473,0.0163149902460927,0.00985115652573246,"TERT/CDK2/CHEK2/PARP1/PPP1CA/CDK1/PSEN2/PPP2CA/PSEN1",9
"GO:0000781","CC","GO:0000781","chromosome, telomeric region","6/173","188/21872",0.00388897302401437,0.0163149902460927,0.00985115652573246,"TERT/CDK2/CHEK2/PARP1/PPP1CA/CDK1",6
"GO:0035631","CC","GO:0035631","CD40 receptor complex","2/173","12/21872",0.00389697665792115,0.0163149902460927,0.00985115652573246,"IKBKB/CHUK",2
"GO:0005938","CC","GO:0005938","cell cortex","8/173","318/21872",0.00390358662329826,0.0163149902460927,0.00985115652573246,"FABP1/NOS2/PRKCB/PTK2/SNCA/RHOA/PSEN2/PSEN1",8
"GO:0098984","CC","GO:0098984","neuron to neuron synapse","9/173","393/21872",0.00417544635791299,0.0172303229453118,0.0104038436899364,"FABP5/BACE1/DRD2/DRD3/SRC/MAPK1/CHRNA3/NOS1/STAT3",9
"GO:0098936","CC","GO:0098936","intrinsic component of postsynaptic membrane","5/173","134/21872",0.00429549910700093,0.0175041588610288,0.010569188592226,"SLC6A3/SLC6A3/DRD2/DRD3/HTR2A",5
"GO:0043679","CC","GO:0043679","axon terminus","5/173","136/21872",0.00457310503439214,0.0184053363112573,0.0111133286735716,"DRD2/PRKCB/NOS1/LRRK2/SNCA",5
"GO:0099568","CC","GO:0099568","cytoplasmic region","7/173","263/21872",0.00504481468623911,0.0200562144843165,0.012110145652461,"FABP1/MAPK1/LRRK2/AKR1B1/MAPT/MAPT/MAPT",7
"GO:0005741","CC","GO:0005741","mitochondrial outer membrane","6/173","200/21872",0.00524458622932661,0.0205992182019334,0.0124380168025881,"BCL2L1/CNR1/MTOR/MAOA/LRRK2/MAOB",6
"GO:0099523","CC","GO:0099523","presynaptic cytosol","2/173","14/21872",0.00531759968701564,0.020637351166275,0.0124610418730818,"PRKCB/LRRK2",2
"GO:0005769","CC","GO:0005769","early endosome","10/173","487/21872",0.00552882228525092,0.0212046595881388,0.0128035884500548,"MAPK3/BACE1/ERBB2/MAPK1/TLR4/EGFR/APP/CFTR/PSEN2/PSEN1",10
"GO:0097060","CC","GO:0097060","synaptic membrane","9/173","416/21872",0.00600927582080476,0.0227793478788645,0.0137544012055139,"SLC6A3/SLC6A3/DRD2/CNR1/DRD3/HTR2A/CHRNA3/PSEN2/PSEN1",9
"GO:1990909","CC","GO:1990909","Wnt signalosome","2/173","15/21872",0.00610394882491844,0.0228047763933576,0.0137697552003806,"GSK3B/LRRK2",2
"GO:0016323","CC","GO:0016323","basolateral plasma membrane","7/173","273/21872",0.00615589056017015,0.0228047763933576,0.0137697552003806,"SLC22A6/ERBB2/EGFR/ABCC1/ABCC1/CD38/C5AR1",7
"GO:0034399","CC","GO:0034399","nuclear periphery","5/173","150/21872",0.00688417599708119,0.0248615275662661,0.0150116424116621,"ALOX5/ALOX5/MAPT/MAPT/MAPT",5
"GO:0008385","CC","GO:0008385","IkappaB kinase complex","2/173","16/21872",0.00693987425929514,0.0248615275662661,0.0150116424116621,"IKBKB/CHUK",2
"GO:0016600","CC","GO:0016600","flotillin complex","2/173","16/21872",0.00693987425929514,0.0248615275662661,0.0150116424116621,"SLC6A3/SLC6A3",2
"GO:0043209","CC","GO:0043209","myelin sheath","3/173","51/21872",0.00766833876731086,0.0268955208977447,0.0162397882075501,"SRD5A1/ERBB2/AKR1B1",3
"GO:0005811","CC","GO:0005811","lipid droplet","4/173","98/21872",0.00767264859966337,0.0268955208977447,0.0162397882075501,"FABP4/CES1/CES1/VCP",4
"GO:0044306","CC","GO:0044306","neuron projection terminus","5/173","155/21872",0.00787773116820643,0.0273206421365457,0.0164964807217761,"DRD2/PRKCB/NOS1/LRRK2/SNCA",5
"GO:0014069","CC","GO:0014069","postsynaptic density","8/173","361/21872",0.00819781519205258,0.0279488024659409,0.0168757702974845,"FABP5/DRD2/DRD3/SRC/MAPK1/CHRNA3/NOS1/STAT3",8
"GO:0032838","CC","GO:0032838","plasma membrane bounded cell projection cytoplasm","6/173","220/21872",0.0082303221985593,0.0279488024659409,0.0168757702974845,"MAPK1/LRRK2/AKR1B1/MAPT/MAPT/MAPT",6
"GO:0031091","CC","GO:0031091","platelet alpha granule","4/173","102/21872",0.00881016102738375,0.0296094071641969,0.0178784602509035,"PLG/SERPINE1/SNCA/APP",4
"GO:0032279","CC","GO:0032279","asymmetric synapse","8/173","367/21872",0.00900324153414933,0.0299495585727825,0.0180838471201496,"FABP5/DRD2/DRD3/SRC/MAPK1/CHRNA3/NOS1/STAT3",8
"GO:0031143","CC","GO:0031143","pseudopodium","2/173","19/21872",0.00973691547593398,0.0320629741934796,0.0193599488995179,"MAPK3/MAPK1",2
"GO:0005814","CC","GO:0005814","centriole","5/173","167/21872",0.0106604889780868,0.0347531940685631,0.020984330935813,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",5
"GO:1904115","CC","GO:1904115","axon cytoplasm","3/173","60/21872",0.011966898691127,0.0386258314188851,0.0233226686320036,"MAPT/MAPT/MAPT",3
"GO:0099572","CC","GO:0099572","postsynaptic specialization","8/173","387/21872",0.0121190735524699,0.0387335095892666,0.0233876858030121,"FABP5/DRD2/DRD3/SRC/MAPK1/CHRNA3/NOS1/STAT3",8
"GO:0098802","CC","GO:0098802","plasma membrane signaling receptor complex","7/173","316/21872",0.0131004583998342,0.0414635867800579,0.0250361340906388,"IGF1R/IL6/ERBB2/IKBKB/CHUK/CHRNA3/INSR",7
"GO:0031519","CC","GO:0031519","PcG protein complex","3/173","63/21872",0.0136508143735175,0.0426458219623626,0.0257499796802125,"CSNK2A1/CSNK2A2/SIRT1",3
"GO:0005770","CC","GO:0005770","late endosome","7/173","319/21872",0.0137356175032149,0.0426458219623626,0.0257499796802125,"MAPK3/BACE1/SRC/MAPK1/LRRK2/EGFR/INSR",7
"GO:0036019","CC","GO:0036019","endolysosome","2/173","23/21872",0.014111480203413,0.0429852937199772,0.0259549561693114,"CTSB/CTSB",2
"GO:0042629","CC","GO:0042629","mast cell granule","2/173","23/21872",0.014111480203413,0.0429852937199772,0.0259549561693114,"PIK3CG/AKR1B1",2
"GO:0005771","CC","GO:0005771","multivesicular body","3/173","64/21872",0.0142405267538575,0.0429852937199772,0.0259549561693114,"BACE1/LRRK2/EGFR",3
"GO:0016605","CC","GO:0016605","PML body","4/173","118/21872",0.0144431572636003,0.0431969657608597,0.0260827658937061,"TERT/CHEK2/MTOR/SIRT1",4
"GO:0043292","CC","GO:0043292","contractile fiber","6/173","251/21872",0.0150206287131432,0.0442648126880491,0.0267275426950765,"IDO1/NOS1/HDAC4/MMP2/PSEN2/PSEN1",6
"GO:0019898","CC","GO:0019898","extrinsic component of membrane","7/173","325/21872",0.0150717613753787,0.0442648126880491,0.0267275426950765,"PLG/SRC/PIK3CA/PIK3CG/PTK2/RHOA/MGLL",7
"GO:0044305","CC","GO:0044305","calyx of Held","2/173","24/21872",0.0153151564326211,0.0445780446163792,0.0269166753092119,"PRKCB/NOS1",2
"GO:0005788","CC","GO:0005788","endoplasmic reticulum lumen","7/173","329/21872",0.0160125050366184,0.0461953685127221,0.0278932318756185,"CES1/CES1/BACE1/PTGS2/IL6/F2/APP",7
"GO:0005637","CC","GO:0005637","nuclear inner membrane","3/173","68/21872",0.0167425204167816,0.0478777338234281,0.0289090611074623,"PTGS2/SIRT1/PSEN2",3
"GO:0002020","MF","GO:0002020","protease binding","18/173","174/20616",7.53606061855826e-15,4.23526606762974e-12,2.64952025957732e-12,"SLC6A3/SLC6A3/SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GSK3B/MIF/MIF/DPP4/VCP/ELANE/ELANE",18
"GO:0004879","MF","GO:0004879","nuclear receptor activity","12/173","57/20616",4.22789682078355e-14,7.09509825239261e-12,4.43858927945145e-12,"NR1H4/PPARA/NR1I3/NR1I2/ESR1/ESR2/RORA/NR1H3/PPARG/NR1H2/STAT3/ESRRA",12
"GO:0098531","MF","GO:0098531","ligand-activated transcription factor activity","12/173","57/20616",4.22789682078355e-14,7.09509825239261e-12,4.43858927945145e-12,"NR1H4/PPARA/NR1I3/NR1I2/ESR1/ESR2/RORA/NR1H3/PPARG/NR1H2/STAT3/ESRRA",12
"GO:0019902","MF","GO:0019902","phosphatase binding","19/173","224/20616",5.04989199458549e-14,7.09509825239261e-12,4.43858927945145e-12,"PPARA/HMGCR/MAPK3/SLC6A3/SLC6A3/PPARG/ERBB2/CSK/MAPK1/AKT1/EGFR/PTK2/PPP1CA/STAT3/MAPK14/MAPT/MAPT/MAPT/VCP",19
"GO:0019903","MF","GO:0019903","protein phosphatase binding","16/173","171/20616",1.2047448841052e-12,1.35413324973424e-10,8.4712587640239e-11,"HMGCR/SLC6A3/SLC6A3/PPARG/ERBB2/CSK/AKT1/EGFR/PTK2/PPP1CA/STAT3/MAPK14/MAPT/MAPT/MAPT/VCP",16
"GO:0004674","MF","GO:0004674","protein serine/threonine kinase activity","23/173","469/20616",1.01972063873127e-11,9.55138331611621e-10,5.97520514624988e-10,"MAPK3/MAPK8/PRKCB/GSK3B/PRKCA/CDK2/CSNK2A1/CSNK2A2/IKBKB/CHEK2/MTOR/PIK3CA/PIK3CG/CDK4/MAPK1/PIM1/CHUK/AKT1/LRRK2/EGFR/MAPK10/MAPK14/CDK1",23
"GO:0008144","MF","GO:0008144","drug binding","13/173","114/20616",1.34945057938154e-11,1.08341603658918e-09,6.77769163178099e-10,"NPC1L1/PPARA/NR1I2/FABP1/SLC6A3/SLC6A3/DRD2/CNR1/PPARG/DRD3/HTR2A/ACE/FASN",13
"GO:0051427","MF","GO:0051427","hormone receptor binding","15/173","187/20616",5.74781037661376e-11,4.03783678957117e-09,2.52601140235394e-09,"NR1H4/FABP4/NR1I2/PTPN11/ESR1/PPARG/PRKCB/NR1H2/SRC/PARP1/SIRT1/STAT5B/STAT3/TYK2/EP300",15
"GO:0047485","MF","GO:0047485","protein N-terminus binding","12/173","127/20616",7.74343533279779e-10,4.83534517448039e-08,3.02492093702276e-08,"SLC6A3/SLC6A3/TERT/MDM2/CSNK2A1/CSNK2A2/PARP1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",12
"GO:0016922","MF","GO:0016922","nuclear receptor binding","11/173","106/20616",1.47295375390596e-09,8.27800009695151e-08,5.17859530320623e-08,"NR1H4/NR1I2/ESR1/PPARG/PRKCB/NR1H2/SRC/PARP1/STAT5B/STAT3/EP300",11
"GO:0035257","MF","GO:0035257","nuclear hormone receptor binding","12/173","154/20616",7.08860423688251e-09,3.62163234647997e-07,2.26564001446771e-07,"NR1H4/NR1I2/ESR1/PPARG/PRKCB/NR1H2/SRC/PARP1/SIRT1/STAT5B/STAT3/EP300",12
"GO:0020037","MF","GO:0020037","heme binding","12/173","157/20616",8.81902738675934e-09,4.13024449279896e-07,2.58382030454177e-07,"CYP19A1/PTGS1/NOS2/IDO1/PTGS2/SRC/NOS3/CYP26A1/NOS1/MPO/NOX4/CYP1B1",12
"GO:0005164","MF","GO:0005164","tumor necrosis factor receptor binding","8/173","51/20616",9.78868098234976e-09,4.23172208621582e-07,2.64730319684601e-07,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0050661","MF","GO:0050661","NADP binding","8/173","53/20616",1.34322114321134e-08,5.39207344631982e-07,3.37320196866608e-07,"G6PD/HMGCR/SRD5A1/NOS2/NOS3/NOS1/GSR/FASN",8
"GO:0051721","MF","GO:0051721","protein phosphatase 2A binding","7/173","36/20616",1.7640832619599e-08,6.06786460624243e-07,3.79596699472742e-07,"HMGCR/SLC6A3/SLC6A3/AKT1/MAPT/MAPT/MAPT",7
"GO:0046906","MF","GO:0046906","tetrapyrrole binding","12/173","167/20616",1.76714233443572e-08,6.06786460624243e-07,3.79596699472742e-07,"CYP19A1/PTGS1/NOS2/IDO1/PTGS2/SRC/NOS3/CYP26A1/NOS1/MPO/NOX4/CYP1B1",12
"GO:0061629","MF","GO:0061629","RNA polymerase II-specific DNA-binding transcription factor binding","15/173","284/20616",1.83547505882778e-08,6.06786460624243e-07,3.79596699472742e-07,"NR1H4/PPARA/NR1I2/ESR1/PPARG/PRKCB/NR1H2/SRC/GSK3B/PARP1/SIRT1/STAT5B/STAT3/MAPK14/EP300",15
"GO:0001618","MF","GO:0001618","virus receptor activity","9/173","91/20616",7.27716489188593e-08,2.07627024349682e-06,1.29888417555336e-06,"HTR2A/EGFR/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/CDK1/DPP4",9
"GO:0140272","MF","GO:0140272","exogenous protein binding","9/173","91/20616",7.27716489188593e-08,2.07627024349682e-06,1.29888417555336e-06,"HTR2A/EGFR/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/CDK1/DPP4",9
"GO:0055131","MF","GO:0055131","C3HC4-type RING finger domain binding","5/173","14/20616",7.39495421712918e-08,2.07627024349682e-06,1.29888417555336e-06,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",5
"GO:0031072","MF","GO:0031072","heat shock protein binding","11/173","155/20616",8.03882044050485e-08,2.07627024349682e-06,1.29888417555336e-06,"CSNK2A1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SNCA/CDK1/MAPT/MAPT/MAPT",11
"GO:0140297","MF","GO:0140297","DNA-binding transcription factor binding","16/173","365/20616",8.12774828415126e-08,2.07627024349682e-06,1.29888417555336e-06,"NR1H4/PPARA/NR1I2/ESR1/PPARG/PRKCB/NR1H2/SRC/GSK3B/PARP1/HDAC4/SIRT1/STAT5B/STAT3/MAPK14/EP300",16
"GO:0005126","MF","GO:0005126","cytokine receptor binding","15/173","324/20616",1.03941828807442e-07,2.53979599086011e-06,1.58885907650736e-06,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/MIF/MIF/CXCL8/STAT3/TYK2/IL2",15
"GO:0032813","MF","GO:0032813","tumor necrosis factor receptor superfamily binding","8/173","69/20616",1.13066854911569e-07,2.64764885251257e-06,1.65633024300281e-06,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF",8
"GO:0004708","MF","GO:0004708","MAP kinase kinase activity","5/173","18/20616",3.07985473196484e-07,6.92351343745696e-06,4.33124833884739e-06,"MAPK3/MAPK1/LRRK2/MAPK10/MAPK14",5
"GO:0005496","MF","GO:0005496","steroid binding","9/173","112/20616",4.38883449141008e-07,9.48663455450948e-06,5.93469927178529e-06,"NR1H4/FABP1/ESR1/ESR2/RORA/NR1H3/AKR1C1/ESRRA/CETP",9
"GO:0004713","MF","GO:0004713","protein tyrosine kinase activity","10/173","149/20616",5.33621772542496e-07,1.11072383766253e-05,6.9485252253097e-06,"IGF1R/SRC/ERBB2/CSK/WEE1/EGFR/INSR/PTK2/ABL1/TYK2",10
"GO:0035258","MF","GO:0035258","steroid hormone receptor binding","8/173","86/20616",6.35732532190894e-07,1.2760060110403e-05,7.98250623126912e-06,"ESR1/PPARG/PRKCB/SRC/PARP1/STAT5B/STAT3/EP300",8
"GO:0004707","MF","GO:0004707","MAP kinase activity","5/173","22/20616",9.21201108774733e-07,1.60316491596196e-05,1.00291642991439e-05,"MAPK3/MAPK8/MAPK1/MAPK10/MAPK14",5
"GO:0005125","MF","GO:0005125","cytokine activity","13/173","286/20616",9.3447754278777e-07,1.60316491596196e-05,1.00291642991439e-05,"TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL6/MIF/MIF/CXCL8/IL2",13
"GO:0097110","MF","GO:0097110","scaffold protein binding","7/173","63/20616",9.66519003876003e-07,1.60316491596196e-05,1.00291642991439e-05,"MAPK3/MDM2/SRC/IKBKB/NOS3/CHUK/NOS1",7
"GO:0035240","MF","GO:0035240","dopamine binding","4/173","10/20616",9.66962222369092e-07,1.60316491596196e-05,1.00291642991439e-05,"SLC6A3/SLC6A3/DRD2/DRD3",4
"GO:0043560","MF","GO:0043560","insulin receptor substrate binding","4/173","10/20616",9.66962222369092e-07,1.60316491596196e-05,1.00291642991439e-05,"PTPN11/IGF1R/PIK3CA/INSR",4
"GO:0097718","MF","GO:0097718","disordered domain specific binding","6/173","40/20616",9.69886248090867e-07,1.60316491596196e-05,1.00291642991439e-05,"MDM2/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",6
"GO:0042826","MF","GO:0042826","histone deacetylase binding","9/173","125/20616",1.11275018437917e-06,1.78675886748883e-05,1.11777011002298e-05,"MAPK8/PARP1/HDAC4/CCND1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",9
"GO:0008022","MF","GO:0008022","protein C-terminus binding","11/173","203/20616",1.20630871835667e-06,1.88318194365681e-05,1.17809097055886e-05,"SREBF2/TERT/PPARG/SRC/ERBB2/CSK/SIRT1/ABL1/PPP2CA/CACNA1B/EP300",11
"GO:0033293","MF","GO:0033293","monocarboxylic acid binding","7/173","73/20616",2.65282545930937e-06,4.02942677873478e-05,2.52075022307064e-05,"NR1H4/FABP4/FABP5/FABP1/PPARG/CYP26A1/AKR1C1",7
"GO:0016705","MF","GO:0016705","oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen","10/173","179/20616",2.83833395939687e-06,4.19774653995011e-05,2.62604859401262e-05,"CYP19A1/PTGS1/NOS2/PTGS2/NOS3/CYP26A1/NOS1/AKR1C1/TYR/CYP1B1",10
"GO:0016653","MF","GO:0016653","oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor","4/173","13/20616",3.22802087948029e-06,4.5501014351577e-05,2.84647664233503e-05,"NOS2/NQO1/NOS3/NOS1",4
"GO:0004712","MF","GO:0004712","protein serine/threonine/tyrosine kinase activity","6/173","49/20616",3.31946901853142e-06,4.5501014351577e-05,2.84647664233503e-05,"MAPK3/MAPK1/AKT1/LRRK2/MAPK10/MAPK14",6
"GO:0004715","MF","GO:0004715","non-membrane spanning protein tyrosine kinase activity","6/173","49/20616",3.31946901853142e-06,4.5501014351577e-05,2.84647664233503e-05,"SRC/CSK/WEE1/PTK2/ABL1/TYK2",6
"GO:0034452","MF","GO:0034452","dynactin binding","4/173","14/20616",4.48964941440389e-06,6.00757850213092e-05,3.7582528932604e-05,"GSK3B/MAPT/MAPT/MAPT",4
"GO:0009055","MF","GO:0009055","electron transfer activity","8/173","114/20616",5.40372531623826e-06,7.06254332029279e-05,4.41822339197938e-05,"CYP19A1/SRD5A1/IDO1/XDH/AKR1B1/GSR/MAOB/NOX4",8
"GO:0050660","MF","GO:0050660","flavin adenine dinucleotide binding","7/173","82/20616",5.81005048223028e-06,7.42101902503049e-05,4.64248052886343e-05,"NOS2/NOS3/NOS1/XDH/GSR/MAOB/NOX4",7
"GO:0001664","MF","GO:0001664","G protein-coupled receptor binding","13/173","339/20616",6.0640932471212e-06,7.513652461076e-05,4.70043064618727e-05,"PTPN11/AGTR1/DRD3/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/ACE/CXCL8/STAT3/TYK2/IL2",13
"GO:0004497","MF","GO:0004497","monooxygenase activity","8/173","116/20616",6.1499646478558e-06,7.513652461076e-05,4.70043064618727e-05,"CYP19A1/NOS2/NOS3/CYP26A1/NOS1/AKR1C1/TYR/CYP1B1",8
"GO:1901338","MF","GO:1901338","catecholamine binding","4/173","16/20616",8.0565278343285e-06,9.63355030402684e-05,6.02660760731404e-05,"SLC6A3/SLC6A3/DRD2/DRD3",4
"GO:0051219","MF","GO:0051219","phosphoprotein binding","7/173","87/20616",8.62163176174667e-06,0.000100944938543784,6.3149671237355e-05,"MAPK3/PTPN11/SRC/MTOR/MAPK1/SNCA/ABL1",7
"GO:0003714","MF","GO:0003714","transcription corepressor activity","10/173","207/20616",1.02829602390824e-05,0.000117644034066392,7.35963801801368e-05,"HDAC4/CCND1/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/SIRT1/ELANE/ELANE",10
"GO:0035173","MF","GO:0035173","histone kinase activity","4/173","17/20616",1.04665510735225e-05,0.000117644034066392,7.35963801801368e-05,"PRKCB/PRKCA/CDK2/CDK1",4
"GO:0051019","MF","GO:0051019","mitogen-activated protein kinase binding","5/173","36/20616",1.19917769119679e-05,0.000132144678912274,8.26677706624825e-05,"PRMT1/ACE/SIRT1/ABL1/MAPK14",5
"GO:0016651","MF","GO:0016651","oxidoreductase activity, acting on NAD(P)H","8/173","129/20616",1.34543924300439e-05,0.000145410933570859,9.09669447699321e-05,"NOS2/NQO1/NOS3/NOS1/GSR/AKR1C1/CBR1/NOX4",8
"GO:0008236","MF","GO:0008236","serine-type peptidase activity","10/173","214/20616",1.37372808272902e-05,0.000145667015564851,9.11271459049637e-05,"PLG/F2/ACE/MMP3/MMP9/CTSG/MMP2/DPP4/ELANE/ELANE",10
"GO:0017171","MF","GO:0017171","serine hydrolase activity","10/173","218/20616",1.61279416850302e-05,0.000167850059759018,0.000105004532608189,"PLG/F2/ACE/MMP3/MMP9/CTSG/MMP2/DPP4/ELANE/ELANE",10
"GO:0044183","MF","GO:0044183","protein folding chaperone","5/173","39/20616",1.79455123228056e-05,0.00018337050773485,0.000114713896953437,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",5
"GO:0031406","MF","GO:0031406","carboxylic acid binding","10/173","224/20616",2.03824537269266e-05,0.000204552482045228,0.000127965029037472,"NR1H4/FABP4/FABP5/FABP1/NOS2/PPARG/NOS3/CYP26A1/NOS1/AKR1C1",10
"GO:0034185","MF","GO:0034185","apolipoprotein binding","4/173","21/20616",2.56388272392449e-05,0.000252789840499222,0.000158141612149729,"PLG/MAPT/MAPT/MAPT",4
"GO:0016616","MF","GO:0016616","oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","8/173","142/20616",2.70003110072813e-05,0.000261623703208484,0.000163667946940689,"AKR1B10/G6PD/HMGCR/LDHB/AKR1B1/AKR1C1/CBR1/FASN",8
"GO:0043177","MF","GO:0043177","organic acid binding","10/173","236/20616",3.18456405262106e-05,0.000303343219927633,0.000189767063974208,"NR1H4/FABP4/FABP5/FABP1/NOS2/PPARG/NOS3/CYP26A1/NOS1/AKR1C1",10
"GO:0016709","MF","GO:0016709","oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen","5/173","45/20616",3.65633374190697e-05,0.000342476593825286,0.000214248328034549,"NOS2/NOS3/CYP26A1/NOS1/AKR1C1",5
"GO:0051787","MF","GO:0051787","misfolded protein binding","5/173","46/20616",4.0745420223457e-05,0.000372541590439207,0.000233056548429847,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",5
"GO:0004252","MF","GO:0004252","serine-type endopeptidase activity","9/173","195/20616",4.10988943189161e-05,0.000372541590439207,0.000233056548429847,"PLG/F2/MMP3/MMP9/CTSG/MMP2/DPP4/ELANE/ELANE",9
"GO:0031625","MF","GO:0031625","ubiquitin protein ligase binding","12/173","350/20616",4.18552881912842e-05,0.000373375745452408,0.000233578383557041,"MDM2/SRC/GSK3B/CHEK2/EGFR/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/MC1R/VCP",12
"GO:0016614","MF","GO:0016614","oxidoreductase activity, acting on CH-OH group of donors","8/173","152/20616",4.3940110787993e-05,0.000385849097857064,0.000241381529657725,"AKR1B10/G6PD/HMGCR/LDHB/AKR1B1/AKR1C1/CBR1/FASN",8
"GO:0004190","MF","GO:0004190","aspartic-type endopeptidase activity","4/173","26/20616",6.19797771389821e-05,0.000535886688493968,0.000335242843148502,"CTSD/BACE1/PSEN2/PSEN1",4
"GO:0003680","MF","GO:0003680","minor groove of adenine-thymine-rich DNA binding","3/173","10/20616",6.67361059458491e-05,0.000559738145778667,0.000350163964581522,"MAPT/MAPT/MAPT",3
"GO:0032052","MF","GO:0032052","bile acid binding","3/173","10/20616",6.67361059458491e-05,0.000559738145778667,0.000350163964581522,"NR1H4/FABP1/AKR1C1",3
"GO:0044389","MF","GO:0044389","ubiquitin-like protein ligase binding","12/173","368/20616",6.7726323688522e-05,0.000559738145778667,0.000350163964581522,"MDM2/SRC/GSK3B/CHEK2/EGFR/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/MC1R/VCP",12
"GO:0070001","MF","GO:0070001","aspartic-type peptidase activity","4/173","27/20616",7.22841363789884e-05,0.000588749052825964,0.000368312762022611,"CTSD/BACE1/PSEN2/PSEN1",4
"GO:0016702","MF","GO:0016702","oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen","4/173","28/20616",8.37813869808165e-05,0.000672644849760269,0.000420796740625454,"ALOX5/ALOX5/IDO1/PTGS2",4
"GO:0001223","MF","GO:0001223","transcription coactivator binding","4/173","29/20616",9.65526053237046e-05,0.000753646724887805,0.000471470324241482,"PPARA/ESR1/RORA/TERT",4
"GO:0016701","MF","GO:0016701","oxidoreductase activity, acting on single donors with incorporation of molecular oxygen","4/173","29/20616",9.65526053237046e-05,0.000753646724887805,0.000471470324241482,"ALOX5/ALOX5/IDO1/PTGS2",4
"GO:0042562","MF","GO:0042562","hormone binding","6/173","91/20616",0.000118318743427544,0.00089361631516436,0.000559033244549346,"TTR/IGF1R/EGFR/INSR/GLP1R/MTNR1A",6
"GO:0004032","MF","GO:0004032","alditol:NADP+ 1-oxidoreductase activity","3/173","12/20616",0.000120844910947493,0.00089361631516436,0.000559033244549346,"AKR1B10/AKR1B1/AKR1C1",3
"GO:0043176","MF","GO:0043176","amine binding","3/173","12/20616",0.000120844910947493,0.00089361631516436,0.000559033244549346,"HTR1A/HTR2A/HTR4",3
"GO:0051378","MF","GO:0051378","serotonin binding","3/173","12/20616",0.000120844910947493,0.00089361631516436,0.000559033244549346,"HTR1A/HTR2A/HTR4",3
"GO:0003707","MF","GO:0003707","steroid hormone receptor activity","4/173","31/20616",0.000126249268564136,0.00092145570042915,0.000576449155166391,"PPARA/ESR1/ESR2/ESRRA",4
"GO:0008353","MF","GO:0008353","RNA polymerase II CTD heptapeptide repeat kinase activity","3/173","13/20616",0.000156129977967897,0.00112493650792254,0.000703743760341129,"CDK4/MAPK1/CDK1",3
"GO:0016209","MF","GO:0016209","antioxidant activity","6/173","100/20616",0.000198857180115328,0.00141465487626347,0.000884987317235438,"FABP1/PTGS1/PTGS2/NQO1/GSR/MPO",6
"GO:0045296","MF","GO:0045296","cadherin binding","11/173","356/20616",0.000217892435842002,0.00153069436179007,0.000957579915410904,"PTPN11/SRC/EGFR/HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A/PPP1CA/FASN/PSEN1",11
"GO:0000217","MF","GO:0000217","DNA secondary structure binding","4/173","36/20616",0.000228751144005267,0.00158713756704889,0.000992889955786346,"ABL1/MAPT/MAPT/MAPT",4
"GO:0015562","MF","GO:0015562","efflux transmembrane transporter activity","3/173","15/20616",0.000245337492340264,0.00166120085174974,0.00103922285912046,"ABCC1/ABCC1/ABCG2",3
"GO:0070402","MF","GO:0070402","NADPH binding","3/173","15/20616",0.000245337492340264,0.00166120085174974,0.00103922285912046,"HMGCR/SRD5A1/FASN",3
"GO:0019825","MF","GO:0019825","oxygen binding","4/173","37/20616",0.000254809249501874,0.0017047952169054,0.00106649485380484,"CYP19A1/CYP26A1/NOX4/CYP1B1",4
"GO:0010181","MF","GO:0010181","FMN binding","3/173","16/20616",0.000300094637995481,0.00198415513592306,0.0012412583169101,"NOS2/NOS3/NOS1",3
"GO:0005504","MF","GO:0005504","fatty acid binding","4/173","40/20616",0.000345756698251933,0.00225947981880914,0.00141349739554646,"FABP4/FABP5/FABP1/PPARG",4
"GO:0001784","MF","GO:0001784","phosphotyrosine residue binding","4/173","42/20616",0.000417977725653468,0.00266743455549092,0.00166870788824493,"MAPK3/PTPN11/MAPK1/ABL1",4
"GO:0030331","MF","GO:0030331","estrogen receptor binding","4/173","42/20616",0.000417977725653468,0.00266743455549092,0.00166870788824493,"ESR1/PPARG/SRC/PARP1",4
"GO:0005324","MF","GO:0005324","long-chain fatty acid transporter activity","3/173","18/20616",0.000431915559696929,0.00266743455549092,0.00166870788824493,"FABP4/FABP5/FABP1",3
"GO:0046965","MF","GO:0046965","retinoid X receptor binding","3/173","18/20616",0.000431915559696929,0.00266743455549092,0.00166870788824493,"NR1H4/PPARG/NR1H2",3
"GO:0070064","MF","GO:0070064","proline-rich region binding","3/173","18/20616",0.000431915559696929,0.00266743455549092,0.00166870788824493,"CSK/CCND1/ABL1",3
"GO:0019213","MF","GO:0019213","deacetylase activity","4/173","44/20616",0.000500365393978057,0.00305657990669204,0.0019121515055912,"CES1/CES1/HDAC4/SIRT1",4
"GO:0051087","MF","GO:0051087","chaperone binding","6/173","119/20616",0.00050788187327753,0.00306913562131153,0.00192000617628404,"PLG/TERT/CFTR/MAPT/MAPT/MAPT",6
"GO:0005506","MF","GO:0005506","iron ion binding","7/173","167/20616",0.000533089120737947,0.00318719240270985,0.00199386076513409,"CYP19A1/ALOX5/ALOX5/CYP26A1/XDH/SNCA/CYP1B1",7
"GO:0048156","MF","GO:0048156","tau protein binding","4/173","46/20616",0.000593697132713603,0.00347560196442755,0.00217428555182394,"GSK3B/SNCA/PPP2CA/EP300",4
"GO:0051879","MF","GO:0051879","Hsp90 protein binding","4/173","46/20616",0.000593697132713603,0.00347560196442755,0.00217428555182394,"CSNK2A1/MAPT/MAPT/MAPT",4
"GO:0030594","MF","GO:0030594","neurotransmitter receptor activity","6/173","123/20616",0.000605065319144498,0.00350563617896091,0.00219307451540165,"DRD2/DRD3/HTR1A/HTR2A/CHRNA3/HTR4",6
"GO:0005518","MF","GO:0005518","collagen binding","5/173","87/20616",0.000832889932202773,0.00477636879487713,0.00298802617997558,"CTSB/CTSB/MMP9/MMP13/MMP12",5
"GO:0001221","MF","GO:0001221","transcription cofactor binding","4/173","51/20616",0.000880065349458853,0.00499592652925127,0.00312537827452692,"PPARA/ESR1/RORA/TERT",4
"GO:0008013","MF","GO:0008013","beta-catenin binding","5/173","90/20616",0.000970889696479509,0.00545640009421484,0.00341344377499111,"ESR1/RORA/GSK3B/EP300/PSEN1",5
"GO:0005158","MF","GO:0005158","insulin receptor binding","3/173","24/20616",0.00103242781773714,0.00574479637196308,0.00359386025142474,"PTPN11/IGF1R/SRC",3
"GO:0045309","MF","GO:0045309","protein phosphorylated amino acid binding","4/173","54/20616",0.00109221396834408,0.00601788480597426,0.00376470036560293,"MAPK3/PTPN11/MAPK1/ABL1",4
"GO:0051117","MF","GO:0051117","ATPase binding","5/173","95/20616",0.00123770473540542,0.00668836597401774,0.00418414353871872,"ESR1/NR1H2/SRC/EGFR/PSEN1",5
"GO:0051213","MF","GO:0051213","dioxygenase activity","5/173","95/20616",0.00123770473540542,0.00668836597401774,0.00418414353871872,"PTGS1/ALOX5/ALOX5/IDO1/PTGS2",5
"GO:0005080","MF","GO:0005080","protein kinase C binding","4/173","58/20616",0.00142768151045155,0.00764149532260735,0.00478040726306584,"PRKCB/SRC/AKT1/ABL1",4
"GO:0046875","MF","GO:0046875","ephrin receptor binding","3/173","27/20616",0.00146473644603217,0.00776586681764227,0.00485821224403918,"SRC/PIK3CG/ABL1",3
"GO:0005319","MF","GO:0005319","lipid transporter activity","6/173","148/20616",0.00157989039260572,0.00829811589387305,0.00519117945037198,"FABP4/FABP5/FABP1/ABCC1/ABCC1/CETP",6
"GO:0016628","MF","GO:0016628","oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor","3/173","28/20616",0.00163045105311833,0.00848438418381947,0.00530770615732479,"SRD5A1/AKR1C1/FASN",3
"GO:0042910","MF","GO:0042910","xenobiotic transmembrane transporter activity","3/173","29/20616",0.00180743933555617,0.00923437187802335,0.00577688744570107,"ABCC1/ABCC1/ABCG2",3
"GO:0042974","MF","GO:0042974","retinoic acid receptor binding","3/173","29/20616",0.00180743933555617,0.00923437187802335,0.00577688744570107,"NR1H4/PPARG/NR1H2",3
"GO:0004693","MF","GO:0004693","cyclin-dependent protein serine/threonine kinase activity","3/173","30/20616",0.00199596809626901,0.00992685017790428,0.00621009170147973,"CDK2/CDK4/CDK1",3
"GO:0008106","MF","GO:0008106","alcohol dehydrogenase (NADP+) activity","3/173","30/20616",0.00199596809626901,0.00992685017790428,0.00621009170147973,"AKR1B10/AKR1B1/AKR1C1",3
"GO:0097472","MF","GO:0097472","cyclin-dependent protein kinase activity","3/173","30/20616",0.00199596809626901,0.00992685017790428,0.00621009170147973,"CDK2/CDK4/CDK1",3
"GO:0030332","MF","GO:0030332","cyclin binding","3/173","31/20616",0.0021962951135231,0.0108273495947367,0.00677343091335841,"CDK2/CDK4/CDK1",3
"GO:0004714","MF","GO:0004714","transmembrane receptor protein tyrosine kinase activity","4/173","70/20616",0.00285443250587557,0.0139494875504528,0.00872659457173859,"IGF1R/ERBB2/EGFR/INSR",4
"GO:0008504","MF","GO:0008504","monoamine transmembrane transporter activity","2/173","10/20616",0.00301423220492181,0.0143559194844581,0.00898085242144412,"SLC6A3/SLC6A3",2
"GO:0016303","MF","GO:0016303","1-phosphatidylinositol-3-kinase activity","2/173","10/20616",0.00301423220492181,0.0143559194844581,0.00898085242144412,"PIK3CA/PIK3CG",2
"GO:0016885","MF","GO:0016885","ligase activity, forming carbon-carbon bonds","2/173","10/20616",0.00301423220492181,0.0143559194844581,0.00898085242144412,"ACACA/ACACA",2
"GO:0001103","MF","GO:0001103","RNA polymerase II repressing transcription factor binding","3/173","35/20616",0.00312043443926104,0.0147368416375185,0.00921915172678627,"PPARA/PPARG/STAT3",3
"GO:0004033","MF","GO:0004033","aldo-keto reductase (NADP) activity","3/173","36/20616",0.00338331473882975,0.0155854334690354,0.00975001831552317,"AKR1B10/AKR1B1/AKR1C1",3
"GO:0004993","MF","GO:0004993","G protein-coupled serotonin receptor activity","3/173","36/20616",0.00338331473882975,0.0155854334690354,0.00975001831552317,"HTR1A/HTR2A/HTR4",3
"GO:0099589","MF","GO:0099589","serotonin receptor activity","3/173","36/20616",0.00338331473882975,0.0155854334690354,0.00975001831552317,"HTR1A/HTR2A/HTR4",3
"GO:0004222","MF","GO:0004222","metalloendopeptidase activity","5/173","120/20616",0.00344346512207048,0.0157335560862082,0.00984268164973504,"MMP3/MMP9/MMP2/MMP13/MMP12",5
"GO:0070491","MF","GO:0070491","repressing transcription factor binding","4/173","74/20616",0.00349056363753823,0.0158201351959394,0.00989684426942079,"PPARA/PPARG/HDAC4/STAT3",4
"GO:0004771","MF","GO:0004771","sterol esterase activity","2/173","11/20616",0.00366379579246992,0.0163416923441913,0.0102231227626145,"CES1/CES1",2
"GO:1990459","MF","GO:1990459","transferrin receptor binding","2/173","11/20616",0.00366379579246992,0.0163416923441913,0.0102231227626145,"IKBKB/CHUK",2
"GO:0071813","MF","GO:0071813","lipoprotein particle binding","3/173","38/20616",0.00394876725103136,0.0173375562115595,0.0108461205743789,"MAPT/MAPT/MAPT",3
"GO:0071814","MF","GO:0071814","protein-lipid complex binding","3/173","38/20616",0.00394876725103136,0.0173375562115595,0.0108461205743789,"MAPT/MAPT/MAPT",3
"GO:0015378","MF","GO:0015378","sodium:chloride symporter activity","2/173","12/20616",0.00437238596877441,0.018902160880394,0.0118249142799243,"SLC6A3/SLC6A3",2
"GO:0035004","MF","GO:0035004","phosphatidylinositol 3-kinase activity","2/173","12/20616",0.00437238596877441,0.018902160880394,0.0118249142799243,"PIK3CA/PIK3CG",2
"GO:0002039","MF","GO:0002039","p53 binding","4/173","79/20616",0.00441311091125737,0.0189325826879896,0.0118439457160302,"MDM2/GSK3B/SIRT1/EP300",4
"GO:0090482","MF","GO:0090482","vitamin transmembrane transporter activity","3/173","40/20616",0.00456843019336737,0.0194504376414581,0.0121679081705319,"ABCC1/ABCC1/ABCG2",3
"GO:0031404","MF","GO:0031404","chloride ion binding","2/173","13/20616",0.00513897796710286,0.0215530269963568,0.013483257195698,"SLC22A6/ACE",2
"GO:0031994","MF","GO:0031994","insulin-like growth factor I binding","2/173","13/20616",0.00513897796710286,0.0215530269963568,0.013483257195698,"IGF1R/INSR",2
"GO:0008201","MF","GO:0008201","heparin binding","6/173","193/20616",0.00585376365635275,0.0243690012953351,0.015244889366252,"F2/MPO/CTSG/APP/ELANE/ELANE",6
"GO:0051082","MF","GO:0051082","unfolded protein binding","5/173","140/20616",0.00659338799701476,0.0272462062817816,0.0170448265557502,"HSPA1A/HSPA1A/HSPA1A/HSPA1A/HSPA1A",5
"GO:0019199","MF","GO:0019199","transmembrane receptor protein kinase activity","4/173","89/20616",0.00672364163018912,0.0272714787393435,0.0170606366340901,"IGF1R/ERBB2/EGFR/INSR",4
"GO:0015373","MF","GO:0015373","anion:sodium symporter activity","2/173","15/20616",0.00684213256627656,0.0272714787393435,0.0170606366340901,"SLC6A3/SLC6A3",2
"GO:0034236","MF","GO:0034236","protein kinase A catalytic subunit binding","2/173","15/20616",0.00684213256627656,0.0272714787393435,0.0170606366340901,"GSK3B/CSK",2
"GO:0035259","MF","GO:0035259","glucocorticoid receptor binding","2/173","15/20616",0.00684213256627656,0.0272714787393435,0.0170606366340901,"STAT5B/STAT3",2
"GO:0036041","MF","GO:0036041","long-chain fatty acid binding","2/173","15/20616",0.00684213256627656,0.0272714787393435,0.0170606366340901,"FABP4/PPARG",2
"GO:0042169","MF","GO:0042169","SH2 domain binding","3/173","47/20616",0.00718387748597865,0.0284319658247888,0.0177866203136907,"SRC/PTK2/ABL1",3
"GO:0001540","MF","GO:0001540","amyloid-beta binding","4/173","91/20616",0.0072657288996365,0.0285548226685015,0.0178634777510386,"BACE1/TLR4/INSR/CACNA1B",4
"GO:0008237","MF","GO:0008237","metallopeptidase activity","6/173","204/20616",0.0076074741187134,0.0289437794053226,0.0181068033739984,"ACE/MMP3/MMP9/MMP2/MMP13/MMP12",6
"GO:0070851","MF","GO:0070851","growth factor receptor binding","5/173","145/20616",0.00762007326874647,0.0289437794053226,0.0181068033739984,"IL6/SRC/APP/IL2/PSEN1",5
"GO:0003953","MF","GO:0003953","NAD+ nucleosidase activity","2/173","16/20616",0.00777670941317386,0.0289437794053226,0.0181068033739984,"TLR4/CD38",2
"GO:0016641","MF","GO:0016641","oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor","2/173","16/20616",0.00777670941317386,0.0289437794053226,0.0181068033739984,"MAOA/MAOB",2
"GO:0017136","MF","GO:0017136","NAD-dependent histone deacetylase activity","2/173","16/20616",0.00777670941317386,0.0289437794053226,0.0181068033739984,"HDAC4/SIRT1",2
"GO:0050135","MF","GO:0050135","NAD(P)+ nucleosidase activity","2/173","16/20616",0.00777670941317386,0.0289437794053226,0.0181068033739984,"TLR4/CD38",2
"GO:0052742","MF","GO:0052742","phosphatidylinositol kinase activity","2/173","16/20616",0.00777670941317386,0.0289437794053226,0.0181068033739984,"PIK3CA/PIK3CG",2
"GO:0061809","MF","GO:0061809","NAD+ nucleotidase, cyclic ADP-ribose generating","2/173","16/20616",0.00777670941317386,0.0289437794053226,0.0181068033739984,"TLR4/CD38",2
"GO:0016538","MF","GO:0016538","cyclin-dependent protein serine/threonine kinase regulator activity","3/173","50/20616",0.00852622208853799,0.0315245843010418,0.0197213170191945,"CDK4/CCNA2/CCND1",3
"GO:0016307","MF","GO:0016307","phosphatidylinositol phosphate kinase activity","2/173","17/20616",0.00876531629499988,0.0315776138319867,0.019754491515047,"PIK3CA/PIK3CG",2
"GO:0016863","MF","GO:0016863","intramolecular oxidoreductase activity, transposing C=C bonds","2/173","17/20616",0.00876531629499988,0.0315776138319867,0.019754491515047,"MIF/MIF",2
"GO:0034979","MF","GO:0034979","NAD-dependent protein deacetylase activity","2/173","17/20616",0.00876531629499988,0.0315776138319867,0.019754491515047,"HDAC4/SIRT1",2
"GO:0050780","MF","GO:0050780","dopamine receptor binding","2/173","17/20616",0.00876531629499988,0.0315776138319867,0.019754491515047,"PTPN11/DRD3",2
"GO:1901682","MF","GO:1901682","sulfur compound transmembrane transporter activity","3/173","51/20616",0.00900410688473045,0.0322312615873791,0.0201634039523967,"ABCC1/ABCC1/ABCG2",3
"GO:0004697","MF","GO:0004697","protein kinase C activity","2/173","18/20616",0.00980699138691273,0.0346637054053142,0.0216851050859242,"PRKCB/PRKCA",2
"GO:0004698","MF","GO:0004698","calcium-dependent protein kinase C activity","2/173","18/20616",0.00980699138691273,0.0346637054053142,0.0216851050859242,"PRKCB/PRKCA",2
"GO:0008227","MF","GO:0008227","G protein-coupled amine receptor activity","3/173","53/20616",0.0100061543128903,0.0351466170240271,0.0219872075033247,"HTR1A/HTR2A/HTR4",3
"GO:1901681","MF","GO:1901681","sulfur compound binding","7/173","286/20616",0.010646554784607,0.0371287344951915,0.0232271910870837,"PRMT1/F2/MPO/CTSG/APP/ELANE/ELANE",7
"GO:0008528","MF","GO:0008528","G protein-coupled peptide receptor activity","5/173","158/20616",0.0108003906862779,0.0371287344951915,0.0232271910870837,"CXCR3/AGTR1/TACR1/MC1R/GLP1R",5
"GO:0015377","MF","GO:0015377","cation:chloride symporter activity","2/173","19/20616",0.0109007850386239,0.0371287344951915,0.0232271910870837,"SLC6A3/SLC6A3",2
"GO:0016500","MF","GO:0016500","protein-hormone receptor activity","2/173","19/20616",0.0109007850386239,0.0371287344951915,0.0232271910870837,"IGF1R/INSR",2
"GO:0019789","MF","GO:0019789","SUMO transferase activity","2/173","19/20616",0.0109007850386239,0.0371287344951915,0.0232271910870837,"MDM2/HDAC4",2
"GO:0051018","MF","GO:0051018","protein kinase A binding","3/173","55/20616",0.0110705185737815,0.0374797074606336,0.0234467546204376,"GSK3B/CSK/LRRK2",3
"GO:0004601","MF","GO:0004601","peroxidase activity","3/173","56/20616",0.0116262779484535,0.0391255581259335,0.0244763746283232,"PTGS1/PTGS2/MPO",3
"GO:0001653","MF","GO:0001653","peptide receptor activity","5/173","162/20616",0.0119373864146324,0.0398218642208033,0.0249119734964381,"CXCR3/AGTR1/TACR1/MC1R/GLP1R",5
"GO:0001972","MF","GO:0001972","retinoic acid binding","2/173","20/20616",0.0120457596397448,0.0398218642208033,0.0249119734964381,"FABP5/CYP26A1",2
"GO:0005326","MF","GO:0005326","neurotransmitter transmembrane transporter activity","2/173","20/20616",0.0120457596397448,0.0398218642208033,0.0249119734964381,"SLC6A3/SLC6A3",2
"GO:0001085","MF","GO:0001085","RNA polymerase II transcription factor binding","3/173","57/20616",0.0121978555212086,0.0398557837379025,0.0249331930482477,"GSK3B/HDAC4/EP300",3
"GO:0017046","MF","GO:0017046","peptide hormone binding","3/173","57/20616",0.0121978555212086,0.0398557837379025,0.0249331930482477,"IGF1R/INSR/GLP1R",3
"GO:0016638","MF","GO:0016638","oxidoreductase activity, acting on the CH-NH2 group of donors","2/173","21/20616",0.0132409894865159,0.0425224919509826,0.0266014465473463,"MAOA/MAOB",2
"GO:0052650","MF","GO:0052650","NADP-retinol dehydrogenase activity","2/173","21/20616",0.0132409894865159,0.0425224919509826,0.0266014465473463,"AKR1B10/AKR1B1",2
"GO:0072349","MF","GO:0072349","modified amino acid transmembrane transporter activity","2/173","21/20616",0.0132409894865159,0.0425224919509826,0.0266014465473463,"ABCC1/ABCC1",2
"GO:0032934","MF","GO:0032934","sterol binding","3/173","59/20616",0.0133887330481715,0.0427526589379114,0.0267454356345054,"RORA/NR1H3/CETP",3
"GO:0016684","MF","GO:0016684","oxidoreductase activity, acting on peroxide as acceptor","3/173","61/20616",0.0146436345987371,0.0464956081609619,0.0290869697054903,"PTGS1/PTGS2/MPO",3
"GO:0019207","MF","GO:0019207","kinase regulator activity","6/173","236/20616",0.0148304054580838,0.0468240891429387,0.0292924625842696,"PIK3CA/CDK4/CCNA2/CCND1/SNCA/IL2",6
"GO:0016627","MF","GO:0016627","oxidoreductase activity, acting on the CH-CH group of donors","3/173","62/20616",0.0152952232083716,0.048021873983826,0.0300417791919796,"SRD5A1/AKR1C1/FASN",3