Term Description p.Val FDR Phenotype Genes NES ES Gene_Hits Gene_Total GLYCOLYSIS AND GLUCONEOGENESIS GLYCOLYSIS AND GLUCONEOGENESIS 0.000104866 0.000264869 -1 "RPTOR,PGRMC2,SARS,MAP1LC3A,SQSTM1,PNP,AARS,GFPT1,TBC1D15,APP,GNPDA1,GARS,XPOT,CTH,PDIA4,TARS,LGALS3BP,GYS1,ASS1,RRAGA,YARS,GALT,HSPA5,ATIC,ABL2,TNIP1,ENO2,AHCYL2,GALE,WARS,GOT1,PEPD,ATP6V1A,CNDP2,ATP6V1B2,CORO1B,MTHFD1,RPS6KA3,PRKAG2,ASNS,IDH1,NARS,PRKAR1A,ATP6V1C1,TSG101,MARK2,GLE1,PGD,PFKM,PGK1,HUWE1,TPI1,UBE2V1,TUBB3,NDUFA4,PRKAR1B,GDI1,IMPDH2,PPP1R7,NDRG1,ATP6V1E1,TUBB4B,PSMD9,IPO4,GAPDH,PRDX1,USP14,CHUK,PFDN2,GSTM3,CTSL,PFKL,IKBKB,ANTXR1,IFRD2,PRDX6,FKBP1A,LARS,MET,NEDD4L,GART,NAP1L1,ACSS2,EPHA2,LDHB,AMDHD2,BCAT1,SEC31A,HGH1,MTMR14,ATN1,APRT,FLNC,BAD,AHSA1,GSTO1,SRRM2,CCS,AKR1A1,IMPA1,GMPPB,PFKP,HSPA6,ADSS,PGM1,OSBPL3,WNK1,MAP2K2,BAG3,UGP2,EIF4EBP1,PEBP1,ADSL,SHMT1,IARS,PRPS2,GMPR2,KEAP1,FASN,CTPS1,ALDOC,PPA1,SRM,MYO1E,XPNPEP1,UBA1,VPS35,MDP1,AHCY,CUL4B,ACO1,IPO5,NADSYN1,EEF2,TAGLN2,ISYNA1,FGFR1,GSPT1,RIC8A,EPRS,PDIA3,GALM,NAP1L4,PRKAA2,TUBA4A,PPP2R4,PYCRL,HSP90B1,HSPH1,PARK7,NUTF2,TTC4,HSPA4,SDSL,NTN4,GDI2,TXLNG,NIF3L1,NAA15,ATG3,TSR1,DSTN,SPRY2,ARFGAP3,LSM14A,PTPN11,OTUD5,GSK3A,PTGES3,EIF2B2,DYNC1H1,ISG15,NPEPPS,FYN,PSMD11,MARS,IPO7,MAP2K1,ENO1,PRKAA1,UBE2M,ALDOA,PRKCI,CCT5,HSP90AA1,POLR3B,DCTN1,CAD,MVK,HNRNPM,ARRB2,FBP1,MYH10,RRM2,EIF2B5,CCT8,ABCE1,DNM1L,NUP62,USP9X,BIN1,ZNFX1,PYGB,STIP1,PPME1,ATF2,UBQLN2,ARPC4,STK10,FNTB,ARAF,EIF4A1,PANK4,PPP2R5D,HGS,DARS,ACTB,ACACA,ACAT2,ALDH3B1,PPID,MAFF,YWHAZ,EGFR,WDR1,HLA-B,PLAA,FHIT,LPIN3,CALR,CAND1,PRDX2,NOTCH2,TSNAX,HINT1,EIF4A2,LDHA,USP5,ADK,PSMB7,HMGCS1,ARPC3,TXN,HSP90AB1,PFDN1,TSC2,CCDC6,PHGDH,LTA4H,CKB,BABAM1,OLA1,PSMB6,VAC14,XPO7,IKBKAP,DDI2,IPO13,PSMB8,TSC22D3,PRKCZ,LSM1,CCT7,PKM,MSN,VCL,AKR1B1,MMS19,YWHAQ,CASP7,CDC42SE1,PTK2,KANK1,PPP4R1,CKS1B,ABCF3,VBP1,SDF2L1,PPIA,PPP2CB,AKR1D1,ZFP36,KRI1,COPB1,GCLC,DVL2,ABCC3,TRAPPC2B,WIPI2,NFKB1,ARHGDIA,HECW2,TP53RK,CCT4,YWHAG,PITPNB,EIF6,PSMD7,SLC35F6,NSFL1C,CCT3,PEA15,NAGK,CASP3,NUDC,DDX3X,KPNB1,PSMA2,KIF23,BMPR1A,STX12,TALDO1,CTPS2,CLK1,BRAF,EIF2S2,STUB1,PLS3,MAP3K3,IRF3,HSPA1B,PAAF1,MAPKAPK3,MAPK1,CAPZA2,ATG5,PTS,DRG2,TRAF3IP1,GPN1,ASNA1,GLO1,CAB39,PPT1,ATP6V1D,UBQLN1,THADA,KIF1B,ELP3,DDX39A,TCP1,MYL1,CSNK1D,RC3H1,MST1R,PFKFB2,NOTCH3,TKT,NOM1,HDAC6,ILK,UBE2V2,PNPO,SH3KBP1,FBXO6,ARFGEF2,CAMKK2,SETD1B,PSMB1,PPP6C,COPA,GMPR,TNPO2,PLS1,USP4,CSE1L,IMPDH1,UBA5,DNAJC21,NFIC,NDUFB8,TUBA1A,BTF3L4,BCAR3,YAP1,CDC37,PSMB2,PSMD6,PFDN4,SNX9,MYH9,PPAN,IKBKG,ISCU,FARSA,COPS5,SZRD1,ATE1,GSPT2,UBE3C,MAP2K3,RAD23B,ARF4,TUBB6,VCP,ARRB1,MPI,FOXO1,TUBB,RAB6C,LPIN1,LSM3,PSMA7,SIRT2,MAT2A,EIF3B,TRAF2,CAP2,ARPC5,WASL,TMEM55A,RMND5A,RAPGEF6,ARFGAP2,GPI,MOB1B,XPO1,ETF1,EXOC2,MCM2,KDELR3,TARDBP,FAM122A,PSMC3,EIF5B,ABCF1,SAR1A,FBXO21,CAP1,STXBP2,BAG6,PPP2R5B,SH3D19,NDUFB1,CLUH,RELA,IDE,PPP3CB,EXOC6,SDCCAG3,MAP3K7,PRMT5,PRUNE,AKT1,ARPC2,AP3D1,EIF2S3,ATP5J2,PSMB3,XPO5" -1.406520259 -0.27327759 450 1831 PYRUVATE METABOLISM PYRUVATE METABOLISM 0.00012566 0.000264869 -1 "AARS,GFPT1,APP,CTH,PDIA4,TARS,LGALS3BP,GALT,HSPA5,ATIC,ENO2,GOT1,ATP6V1A,CNDP2,ATP6V1B2,MTHFD1,ASNS,PRKAR1A,MARK2,PGD,PFKM,HUWE1,TUBB3,PRKAR1B,GDI1,ATP6V1E1,TUBB4B,IPO4,GAPDH,CTSL,PFKL,ANTXR1,FKBP1A,LARS,NEDD4L,NAP1L1,ACSS2,GSTO1,AKR1A1,GMPPB,PFKP,HSPA6,WNK1,MAP2K2,BAG3,UGP2,SHMT1,IARS,PRPS2,FASN,CTPS1,PPA1,UBA1,AHCY,IPO5,EEF2,ISYNA1,EPRS,PDIA3,RPAP3,NAP1L4,PRKAA2,TUBA4A,PYCRL,HSPH1,NUTF2,HSPA4,SDSL,GDI2,SGTA,PTGES3,ISG15,NPEPPS,PSMD11,ENO1,PRKAA1,ALDOA,HSP90AA1,POLR3B,CAD,RRM2,CCT8,STIP1,ARPC4,EIF4A1,ACTB,ACACA,ACAT2,PPID,EGFR,HLA-B,CALR,CAND1,PRDX2,HINT1,EIF4A2,ADK,ARPC3,TXN,HSP90AB1,LTA4H,CCT7,PKM,MSN,AKR1B1,MMS19,ABCF3,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,AKR7A2,NFKB1,ARHGDIA,HECW2,CCT4,PSMD7,CCT3,TALDO1,IST1,CTPS2,PLS3,AKR1C3,HSPA1B,MAPK1,ATG5,CARHSP1,GPN1,GLO1,ATP6V1D,TCP1,MYL1,CSNK1D,TKT,PPP6C,COPA,PLS1,CSE1L,TUBA1A,CDC37,PSMD6,PFDN4,IKBKG,ARF4,TUBB6,VCP,TUBB,PSMA7,MAT2A,EIF3B,ARPC5,WASL,GPI,XPO1,MAP7D1,MCM2,CLUH,MAP3K7,ARPC2,EIF2S3,XPO5,TUBB4A,VHL,PRDX5,TRAF4,ASL,TCEB2,ACTR2" -2.094188759 -0.43622086 169 448 DI-UNSATURATED FATTY ACID BETA-OXIDATION DI-UNSATURATED FATTY ACID BETA-OXIDATION 0.000123198 0.000264869 -1 "PGRMC2,MAP1LC3A,SQSTM1,GFPT1,APP,XPOT,LAMP1,PDIA4,RRAGA,GALT,HSPA5,ENO2,CALCOCO2,ATP6V1A,ATP6V1B2,PAICS,PFKM,PGK1,HUWE1,TUBB3,NDUFA4,GDI1,NDRG1,TUBB4B,IPO4,GAPDH,PFKL,IFRD2,FKBP1A,LARS,NEDD4L,GART,GSTO1,GMPPB,PFKP,HSPA6,PGM1,BAG3,CTPS1,SPG20,ABHD14B,UBA1,TIMP2,ARMC6,AHCY,MAPRE1,EEF2,ISYNA1,PDIA3,PRKAA2,TUBA4A,PYCRL,HSPH1,PARK7,HSPA4,SDSL,GDI2,GTPBP2,DBNL,PTGES3,EIF2B2,IPO7,ENO1,ALDOA,HSP90AA1,CAD,RRM2,EIF2B5,CCT8,PYGB,STIP1,ATF2,EIF4A1,HGS,TNIK,DARS,ACTB,ACACA,AK1,PPID,YWHAZ,EGFR,HLA-B,CALR,STAT1,HINT1,EIF4A2,ADK,HSP90AB1,SLC1A5,OLA1,RNASEH2A,MSN,VCL,MMS19,YWHAQ,NT5C2,PPP2CB,HECW2,PSMD7,ABCG1,CLDN12,KPNB1,CTPS2,CLK1,EIF2S2,PLS3,HSPA1B,MAPK1,ATG5,GPN1,ATP6V1D,CSNK1D,TKT,NOM1,FBXO6,FERMT2,PPP6C,TNPO2,PLS1,CSE1L,UBA5,TUBA1A,PFDN4,MYH9,FARSA,COPS5,TUBB6,VCP,TUBB,GET4,LAMP2,MAT2A,WASL,GPI,MOB1B,SLC27A1,XPO1,MCM2,PSMC3,TUBGCP3,BAG6,CLUH,IDE,BAIAP2,PPP3CB,RABAC1,FTSJ1,CCDC22,EIF2S3" -1.653010962 -0.341063836 150 500 HEXOSE PHOSPHORYLATION HEXOSE PHOSPHORYLATION 0.00012213 0.000264869 -1 "SARS,AARS,GFPT1,APP,GARS,XPOT,CTH,PDIA4,TARS,GYS1,ASS1,GALT,HSPA5,ATIC,GYG1,ENO2,GOT1,ATP6V1A,CNDP2,ATP6V1B2,MTHFD1,NARS,PRKAR1A,ATP6V1C1,PGD,PFKM,TUBB3,NDUFA4,PRKAR1B,GDI1,PPP1R7,ATP6V1E1,TUBB4B,PSMD9,IPO4,GAPDH,PFKL,FKBP1A,LARS,NEDD4L,GART,NAP1L1,G6PD,ACSS2,BCAT1,HGH1,CCS,AKR1A1,GMPPB,PFKP,HSPA6,PGM1,MAP2K2,UGP2,ADSL,SHMT1,IARS,PRPS2,CTPS1,ALDOC,PPA1,SRM,MYO1E,UBA1,AHCY,IPO5,NADSYN1,EEF2,ISYNA1,PDIA3,NAP1L4,PRKAA2,TUBA4A,PYCRL,HSPH1,NUTF2,HSPA4,SDSL,GDI2,SGTA,TSR1,DSTN,GSK3A,EIF2B2,NPEPPS,PSMD11,IPO7,ENO1,PRKCI,CCT5,HSP90AA1,POLR3B,CAD,RRM2,EIF2B5,CCT8,DNM1L,PYGB,STIP1,ATF2,ARPC4,EIF4A1,DARS,ACTB,ACACA,ACAT2,PPID,YWHAZ,EGFR,PRDX2,EIF4A2,ADK,HMGCS1,ARPC3,TXN,HSP90AB1,OLA1,LSM1,CCT7,MMS19,YWHAQ,PPIA,PPP2CB,AKR1D1,KRI1,NFKB1,FAT1,CCT4,EIF6,PSMD7,NSFL1C,CCT3,PEA15,NAGK,KPNB1,TALDO1,CTPS2,EIF2S2,PLS3,AP3M2,IRF3,HSPA1B,MAPK1,ATG5,GPN1,ATP6V1D,UBQLN1,TCP1,MYL1,CSNK1D,TKT,PNPO,FBXO6,ARFGEF2,PPP6C,COPA,TNPO2,PLS1,CSE1L,DNAJC21,TUBA1A,BTF3L4,FARSA,COPS5,UBE3C,RAD23B,ARF4,TUBB6,VCP,MPI,TUBB,MAT2A,ARPC5,WASL,GPI,MOB1B,XPO1,ETF1" -2.099662165 -0.431737986 178 522 GALACTOSE METABOLISM GALACTOSE METABOLISM 0.000114103 0.000264869 -1 "SARS,AARS,GFPT1,APP,GARS,XPOT,CTH,PDIA4,TARS,GYS1,ASS1,RRAGA,GALT,HSPA5,ATIC,GYG1,ENO2,GOT1,PEPD,ATP6V1A,ATP6V1B2,MTHFD1,ASNS,IDH1,NARS,PRKAR1A,ATP6V1C1,PGD,PFKM,PGK1,HUWE1,UBE2V1,TUBB3,NDUFA4,PRKAR1B,GDI1,IMPDH2,PPP1R7,ATP6V1E1,TUBB4B,IPO4,GAPDH,PRDX1,PFKL,FKBP1A,LARS,NEDD4L,GART,NAP1L1,ACSS2,LDHB,BCAT1,SEC31A,HGH1,ATN1,APRT,AHSA1,GSTO1,AKR1A1,GMPPB,PFKP,HSPA6,PGM1,WNK1,MAP2K2,BAG3,UGP2,SHMT1,IARS,CTPS1,ALDOC,PPA1,MYO1E,UBA1,AHCY,CUL4B,IPO5,EEF2,ISYNA1,PDIA3,NAP1L4,PRKAA2,TUBA4A,PYCRL,HSPH1,NUTF2,HSPA4,SDSL,GDI2,SGTA,NIF3L1,NAA15,TSR1,DSTN,GSK3A,PTGES3,EIF2B2,DYNC1H1,ISG15,NPEPPS,PSMD11,MARS,IPO7,ENO1,UBE2M,ALDOA,CCT5,HSP90AA1,TRIP13,POLR3B,CAD,MYH10,RRM2,GALK1,EIF2B5,CCT8,ABCE1,GPSM1,DNM1L,PYGB,STIP1,PPME1,ATF2,ARPC4,EIF4A1,PPP2R5D,HGS,PCBP1,DARS,ACTB,ACACA,ACAT2,PPID,YWHAZ,EGFR,WDR1,HLA-B,CALR,PRDX2,NOTCH2,TSNAX,HINT1,EIF4A2,LDHA,ADK,PSMB7,HMGCS1,ARPC3,TXN,HSP90AB1,LTA4H,CKB,OLA1,PSMB6,VAC14,PSMB8,LSM1,CCT7,PKM,MSN,AKR1B1,MMS19,YWHAQ,ABCF3,VBP1,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,WIPI2,AKR7A2,NFKB1,ARHGDIA,HECW2,TP53RK,CCT4,EIF6,PSMD7,CCT3,KPNB1,PSMA2,BMPR1A,TALDO1,IST1,CTPS2,EIF2S2,PLS3,MAP3K3,AKR1C3,HSPA1B,PAAF1,MAPK1,CAPZA2,ATG5,CARHSP1,GPN1,GLO1,ATP6V1D,UBQLN1,TCP1,SNX24,CSNK1D,RC3H1,NOTCH3,TKT,NOM1,HDAC6,ILK,UBE2V2,FBXO6,PSMB1,PPP6C,COPA,PLS1,CSE1L,IMPDH1,DNAJC21,NDUFB8,TUBA1A,BTF3L4,BCAR3,PSMB2,PSMD6,PFDN4,SNX9,MYH9,PPAN,FARSA,COPS5,ATE1,MAP2K3,RAD23B,ARF4,TUBB6,VCP,ARRB1,MPI,TUBB,PSMA7,MAT2A,EIF3B,TRAF2,ARPC5,WASL,GPI,MOB1B,XPO1,MEPCE,ETF1,MCM2,KDELR3,PSMC3,EIF5B,ABCF1,SAR1A,PPP2R5B,NDUFB1,CLUH,IDE,PPP3CB,EXOC6,MAP3K7,PRMT5,PRUNE,AKT1,ARPC2,EIF2S3,PSMB3,TUBB4A,BUB1,SEC23B,VHL,PRDX5,PSMA1,ASL,PSMA5,ACTR2,PSMB9,EIF2B3,UFL1,FLCN" -1.739954855 -0.346813495 282 908 HISTIDINE METABOLISM HISTIDINE METABOLISM 0.000117952 0.000264869 -1 "SARS,MAP1LC3A,AARS,GFPT1,TBC1D15,APP,GARS,XPOT,CTH,PDIA4,TARS,LGALS3BP,GYS1,ASS1,GALT,HSPA5,ATIC,ENO2,GALE,GOT1,ATP6V1A,CNDP2,ATP6V1B2,MTHFD1,IDH1,NARS,PRKAR1A,ATP6V1C1,PGD,PFKM,HUWE1,TUBB3,PRKAR1B,GDI1,IMPDH2,PPP1R7,NDRG1,ATP6V1E1,TUBB4B,IPO4,GAPDH,PFDN2,PFKL,FKBP1A,LARS,NEDD4L,GART,NAP1L1,ACSS2,BCAT1,UGCG,AKR1A1,GMPPB,PFKP,HSPA6,PGM1,MAP2K2,BAG3,UGP2,HARS,SHMT1,IARS,CTPS1,PPA1,SRM,MYO1E,UBA1,AHCY,IPO5,EEF2,ISYNA1,PDIA3,NAP1L4,PRKAA2,TUBA4A,PYCRL,HSPH1,NUTF2,HSPA4,SDSL,GDI2,KIF5B,TSR1,DSTN,EIF2B2,SH3GL1,NPEPPS,PSMD11,MARS,ENO1,PRKCI,CCT5,HSP90AA1,POLR3B,CAD,MYH10,RRM2,EIF2B5,CCT8,PYGB,STIP1,EIF4A1,TNIK,DARS,ACTB,ACACA,ACAT2,ALDH3B1,PPID,EGFR,PLAA,FHIT,CAND1,PRDX2,EIF4A2,ADK,HMGCS1,HSP90AB1,TSC2,OLA1,IPO13,TSC22D3,LSM1,CCT7,MMS19,CKS1B,ABCF3,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,GCLC,CCT4,EIF6,PSMD7,SLC35F6,NSFL1C,CCT3,KPNB1,TALDO1,CTPS2,CLK1,EIF2S2,PLS3,HSPA1B,PAAF1,MAPK1,CAPZA2,DRG2,GPN1,ATP6V1D,THADA,TCP1,MYL1,CSNK1D,TKT,NOM1,FBXO6,ARFGEF2,SETD1B,PPP6C,COPA,TNPO2,PLS1,CSE1L,IMPDH1,UBA5,TUBA1A,BTF3L4,PSMD6,MYH9,PPAN,FARSA,UBE3C,ARF4,TUBB6,VCP,MPI,TUBB,MAT2A,CAP2,GPI,MOB1B,SLC27A1,XPO1,MCM2,PSMC3,EIF5B,CAP1,SOAT1,CLUH,RELA,IDE,PPP3CB" -1.679542886 -0.339545409 195 686 BILE ACID BIOSYNTHESIS BILE ACID BIOSYNTHESIS 0.00011207 0.000264869 -1 "SARS,MAP1LC3A,SQSTM1,AARS,GFPT1,TBC1D15,APP,GARS,XPOT,CTH,LAMP1,PDIA4,TARS,LGALS3BP,GYS1,ASS1,NDST1,GALT,HSPA5,ATIC,TNIP1,ENO2,GALE,WARS,GOT1,ATP6V1A,CNDP2,ATP6V1B2,MTHFD1,RPS6KA3,NARS,PRKAR1A,ATP6V1C1,PGD,PFKM,HUWE1,UBE2V1,TUBB3,PRKAR1B,GDI1,IMPDH2,PPP1R7,ATP6V1E1,TUBB4B,PSMD9,IPO4,GAPDH,PRDX1,CTSL,PFKL,FKBP1A,VPS4B,LARS,NEDD4L,GART,NAP1L1,ACSS2,LDHB,BCAT1,SEC31A,IPO9,APRT,AHSA1,GSTO1,SRRM2,AKR1A1,GMPPB,CDK6,PFKP,HSPA6,PGM1,MAP2K2,BAG3,NAE1,UGP2,ADSL,SHMT1,IARS,FASN,CTPS1,PPA1,SRM,MYO1E,UBA1,ARMC6,AHCY,IPO5,EEF2,ISYNA1,EPRS,PDIA3,NAP1L4,PRKAA2,VTA1,TUBA4A,PYCRL,HSP90B1,HSPH1,NUTF2,HSPA4,SDSL,GDI2,TSR1,DSTN,MRPS17,PTGES3,EIF2B2,ISG15,NPEPPS,PSMD11,MARS,DYRK1A,ENO1,UBE2M,ALDOA,PRKCI,CCT5,HSP90AA1,POLR3B,CAD,ARRB2,MYH10,WWP2,RRM2,EIF2B5,CCT8,ABCE1,GPSM1,DNM1L,NUP62,USP9X,PYGB,STIP1,ATF2,EIF4A1,UBE2R2,ESD,DARS,ACTB,ACACA,ACAT2,AK1,PPID,YWHAZ,EGFR,PLAA,FHIT,CALR,CAND1,PRDX2,CDK5,HINT1,EIF4A2,LDHA,ADK,HMGCS1,HSP90AB1,TSC2,OLA1,IPO13,SPINT2,LSM1,CCT7,MSN,VCL,AKR1B1,MMS19,YWHAQ,CKS1B,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,GCLC,AKR7A2,HECW2,CCT4,YWHAG,EIF6,PSMD7,ABCG1,SLC35F6,NSFL1C,CCT3,CASP3,DDX3X,KPNB1,BMPR1A,TALDO1,CTPS2,EIF2S2,PLS3,AKR1C3,HSPA1B,PAAF1,MAPK1,CAPZA2,ATG5,DRG2,CARHSP1,GPN1,ATP6V1D,UBQLN1,THADA,DDX39A,TCP1,MYL1,CSNK1D,TKT,NOM1,FBXO6,SETD1B,PPP6C,COPA,TNPO2,PLS1,CSE1L,IMPDH1,UBA5,ARHGAP1,TUBA1A,CHST11,BTF3L4,PSMD6,PFDN4,MYH9,PPAN,FARSA,CHCHD2,UBE3C,CDC34,RAD23B,ARF4,TUBB6,VCP,ARRB1,MPI" -1.477145324 -0.292755374 238 1023 PROPANOATE METABOLISM PROPANOATE METABOLISM 0.000114286 0.000264869 -1 "SARS,MAP1LC3A,SQSTM1,AARS,GFPT1,TBC1D15,APP,GARS,XPOT,CTH,PDIA4,TARS,LGALS3BP,GYS1,ASS1,GALT,HSPA5,ATIC,ENO2,GALE,WARS,GOT1,ATP6V1A,CNDP2,ATP6V1B2,MTHFD1,NARS,PRKAR1A,ATP6V1C1,PGD,PFKM,PGK1,HUWE1,TUBB3,PRKAR1B,GDI1,IMPDH2,PPP1R7,NDRG1,ATP6V1E1,TUBB4B,IPO4,GAPDH,CTSL,PFKL,IFRD2,FKBP1A,VPS4B,LARS,NEDD4L,GART,NAP1L1,ACSS2,LDHB,BCAT1,IPO9,APRT,AHSA1,CCS,AKR1A1,GMPPB,PFKP,HSPA6,PGM1,MAP2K2,NAE1,UGP2,SHMT1,IARS,FASN,CTPS1,PPA1,SRM,MYO1E,ABHD14B,UBA1,TIMP2,AHCY,CUL4B,AACS,IPO5,EEF2,ISYNA1,EPRS,PDIA3,NAP1L4,PRKAA2,TUBA4A,PYCRL,HSP90B1,HSPH1,PARK7,NUTF2,HSPA4,SDSL,GDI2,GTPBP2,TSR1,DSTN,PTGES3,EIF2B2,ISG15,NPEPPS,PSMD11,MARS,ENO1,UBE2M,ALDOA,PRKCI,CCT5,HSP90AA1,POLR3B,CAD,ARRB2,PUS7,MYH10,WWP2,RRM2,EIF2B5,CCT8,ABCE1,PYGB,STIP1,PPME1,ATF2,EIF4A1,UBE2R2,PANK4,TNIK,DARS,ACTB,ACACA,ACAT2,AK1,PPID,YWHAZ,EGFR,HLA-B,PLAA,FHIT,CAND1,PRDX2,EIF4A2,LDHA,ADK,HMGCS1,TXN,HSP90AB1,TSC2,CKB,OLA1,VAC14,IPO13,SPINT2,LSM1,CCT7,PKM,VCL,MMS19,YWHAQ,PPP4R1,CKS1B,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,GCLC,CCT4,EIF6,PSMD7,SLC35F6,CLDN12,NSFL1C,CCT3,KPNB1,TALDO1,CTPS2,EIF2S2,PLS3,HSPA1B,PAAF1,MAPK1,CAPZA2,ATG5,DRG2,GPN1,ATP6V1D,THADA,DDX39A,TCP1,MYL1,CSNK1D,TKT,NOM1,FBXO6,SETD1B,FERMT2,PPP6C,COPA,TNPO2,PLS1,CSE1L,IMPDH1,UBA5,TUBA1A,BTF3L4,PSMD6,MYH9,PPAN,UMPS,FARSA,COPS5,UBE3C,CDC34,RAD23B,ARF4,TUBB6,VCP,ARRB1,MPI,TUBB,VPS4A,MAT2A,GPI,MOB1B,SLC27A1,XPO1,MCM2,KDELR3,PSMC3,EIF5B,ABCF1,RABIF,BAG6,CLUH,IDE,PPP3CB,FTSJ1,PRMT5,PRUNE,AKT1,PARG,EIF2S3,MMAA,TUBB4A,UBE2E2,BUB1,SEC23B,VHL,PRDX5,TRAF4,ASL" -1.623977249 -0.323824352 253 899 ANDROGEN AND ESTROGEN BIOSYNTHESIS AND METABOLISM ANDROGEN AND ESTROGEN BIOSYNTHESIS AND METABOLISM 0.000113058 0.000264869 -1 "PGRMC2,SARS,MAP1LC3A,SQSTM1,AARS,GFPT1,APP,F10,GARS,CTH,PDIA4,TARS,SNX2,PDCD6IP,NDST1,YARS,GALT,HSPA5,ATIC,ACY1,ENO2,SLC3A2,GOT1,ATP6V1A,CNDP2,ATP6V1B2,CORO1B,MTHFD1,RPS6KA3,PRKAG2,NARS,PRKAR1A,ATP6V1C1,MARK2,PGD,PFKM,PGK1,HUWE1,PDIA6,TUBB3,PRKAR1B,GDI1,EIF2A,ATP6V1E1,TUBB4B,PSMD9,IPO4,GAPDH,PRDX1,GSTM3,PFKL,IKBKB,PRDX6,FKBP1A,LARS,CRKL,NEDD4L,TGM2,BLMH,ACSS2,PDXDC1,BCAT1,SEC31A,APRT,BAD,AHSA1,GSTO1,AKR1A1,GMPPB,RAB3GAP1,PFKP,HSPA6,ADSS,PGM1,BAG3,UGP2,GSTM1,TAX1BP1,EIF4EBP1,HARS,SHMT1,IARS,KEAP1,CTPS1,ARFGAP1,PPA1,SRM,XPNPEP1,PSME1,UBA1,AHCY,CUL4B,ACO1,EEF2,ISYNA1,GSPT1,PDIA3,PRKAA2,SLC2A3,TUBA4A,PYCRL,HSPH1,NUTF2,HSPA4,SDSL,GDI2,NAA15,ALAD,NCK1,DSTN,NAA50,GSTCD,RIN1,DBNL,PTPN11,EIF2B2,ISG15,NPEPPS,ENO1,PRKAA1,CLIC1,ALDOA,HSP90AA1,DOPEY2,TRIP13,POLR3B,DCTN1,CAD,HNRNPM,ARRB2,RRM2,DERA,EIF2B5,CCT8,DNM1L,PIK3R1,UGDH,PYGB,STIP1,EPS8L2,ATF2,EIF4A1,PPP2R5D,GSTP1,PCBP1,DARS,ACTB,ACACA,ACAT2,IFIT5,YWHAZ,EGFR,CRK,CAND1,PRDX2,STAT1,TSNAX,SH3GLB1,EIF4A2,ADK,MLLT4,ARL1,HMGCS1,TXN,HSP90AB1,SLC1A5,UBE2O,ARMT1,BABAM1,OLA1,XPO7,IKBKAP,TPP2,RNASEH2A,LSM1,SNX3,PKM,MSN,AKR1B1,MMS19,YWHAQ,CKS1B,ABCF3,PPIA,PPP2CB,AKR1D1,KRI1,DVL2,AKR7A2,DCTN3,NFKB1,HECW2,YWHAG,ALDH16A1,EIF6,PSMD7,SHC1,NSFL1C,CCT3,SRXN1,TALDO1,CTPS2,CLK1,BRAF,EIF2S2,PLS3,AKR1C3,IRF3,HSPA1B,MAPK1,ATG5,PTS,PSMF1,CAB39,PPT1,APOB,RAB3GAP2,CSNK1D,GNB1L,HDAC6,FBXO6,ARFGEF2,CHMP3,COPA,EPS15,PLS1,CSE1L,UBA5,TMX2,PIP4K2A,TUBA1A,CHST11,BTF3L4,OGFR,PLCG1,CDC37,DTD1,PSMB2,PSMD6,FARSA,COPS5,LCN2,GSPT2,RAD23B,ARF4,TUBB6,VCP,ARRB1,MPI,CD2AP,TUBB,LSM3,VPS51,DCUN1D1,MAT2A,GAN,TRAF2,GPI,PTPRK,XPO1,ETF1,RTN4,MCM2,PSMC3,ABCF1,BMPR2,IQGAP1,PPP2R5B,SOAT1,TCEA1,CLUH,PPP3CB,EXOC6,MAP3K7,PRMT5,ARPC2,EIF2S3,PSMB3,XPO5,SBDS,TUBB4A,BUB1,PXN,SEC23B,VHL,PRDX5,PRKAB2,TRAF4,ASL,CD320" -1.707593696 -0.33937685 290 969 "GLYCINE, SERINE, ALANINE AND THREONINE METABOLISM" "GLYCINE, SERINE, ALANINE AND THREONINE METABOLISM" 0.000110461 0.000264869 -1 "SDCBP,SARS,MAP1LC3A,SQSTM1,AARS,HSPB1,GFPT1,APP,GARS,CTH,PSAT1,PDIA4,TARS,GYS1,ASS1,YARS,GALT,HSPA5,ATIC,ACY1,ENO2,WARS,GOT1,SNX8,CALCOCO2,PTER,ATP6V1A,ATP6V1B2,MTHFD1,COPRS,PRKAG2,ASNS,IDH1,NARS,PRKAR1A,ATP6V1C1,PTPRS,PGD,PFKM,PGK1,HUWE1,TPI1,TBCE,TUBB3,NDUFA4,PRKAR1B,GDI1,IMPDH2,PPP1R7,NDRG1,ATP6V1E1,TUBB4B,IPO4,GAPDH,PFKL,NAMPT,FKBP1A,VPS4B,LARS,NEDD4L,GART,NAP1L1,ACSS2,LDHB,BCAT1,SEC31A,APRT,AHSA1,GSTO1,AKR1A1,GMPPB,SCRIB,PFKP,HSPA6,PGM1,MAP2K2,BAG3,NAE1,UGP2,PEBP1,ADSL,SHMT1,IARS,PRPS2,GMPR2,FASN,CTPS1,ALDOC,PPA1,MYO1E,XPNPEP1,UBA1,TIMP2,NDOR1,AHCY,ACO1,MAPRE1,EEF2,TAGLN2,ISYNA1,RIC8A,EPRS,PDIA3,PAFAH1B1,ELP4,RPAP3,NAP1L4,TUBA4A,HSPH1,PSPH,NUTF2,HSPA4,SDSL,NTN4,GDI2,SGTA,NIF3L1,TSR1,DSTN,MRPS17,CLN3,PTGES3,EIF2B2,ISG15,NPEPPS,PSMD11,SH2D4A,ENO1,ALDOA,CCT5,HSP90AA1,TRIP13,POLR3B,CAD,HNRNPM,RRM2,CCT8,ABCE1,DNM1L,BIN1,ZNFX1,PYGB,STIP1,PPME1,LIN9,CHMP2B,ATF2,STK10,EIF4A1,HGS,TRERF1,GSTP1,TNIK,DARS,ACTB,ACACA,ACAT2,PPID,YWHAZ,EGFR,HLA-B,CALR,CAND1,PRDX2,CDK5,HINT1,HEBP2,EIF4A2,LDHA,ADK,HMGCS1,TXN,HSP90AB1,UBR4,PHGDH,CKB,BABAM1,OLA1,PIN4,DDI2,RNASEH2A,LSM1,CCT7,PKM,MSN,MMS19,YWHAQ,KANK1,ABCF3,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,TP53RK,CCT4,YWHAG,ALDH16A1,EIF6,PSMD7,ABCG1,PPAT,NSFL1C,CCT3,BMPR1A,TALDO1,CTPS2,IFNGR1,EIF2S2,PLS3,TNFRSF10D,MAP3K3,HSPA1B,MAPK1,TRAF3IP1,GPN1,ASNA1,GLO1,IL18,TCP1,S100A11,CSNK1D,RC3H1,TKT,KPNA3,HDAC6,ILK,PRPSAP1,FBXO6,PPP6C,COPA,GMPR,PLS1,CSE1L,IMPDH1,UBA5,FUNDC2,TUBA1A,BTF3L4,BCAR3,CDC37,TTC39C,PSMB2,PSMD6,PFDN4,JMY,PPAN,IKBKG,FNBP1,FARSA,ATE1,TTC1,CHCHD2,RAD23B,ARF4,TUBB6,VCP,ARRB1,MPI,FOXO1,TUBB,PSMA7,VPS4A,SIRT2,MAT2A,ATAD3A,NEK7,CAP2,CIRBP,RAPGEF6,GPI,MOB1B,XPO1,MEPCE,ETF1,EXOC2,MCM2,TARDBP,PSMC3,EIF5B,ABCF1,SAR1A,SSH3,PDCL3,MRM1,TUBGCP3,FBXO21,CAP1,CLUH,IDE,WIPF1,INPPL1,FTSJ1,NUDT3,PRMT5,PRUNE,AKT1,PARG,EIF2S3,PSMB3,NMI,KIAA1217,TUBB4A,NT5C3B,PXN,SEC23B,VHL,PRDX5,PRKAB2,ASL,DDX52,KCMF1,ACTR2" -1.609480134 -0.317461572 313 1134 LIPOATE METABOLISM LIPOATE METABOLISM 0.000124471 0.000264869 -1 "SARS,MAP1LC3A,AARS,GFPT1,PDIA4,TARS,GYS1,ASS1,GALT,HSPA5,ENO2,GOT1,PEPD,ATP6V1A,ATP6V1B2,MTHFD1,RPS6KA3,ASNS,IDH1,PRKAR1A,ATP6V1C1,PGD,PFKM,PGK1,HUWE1,TPI1,TUBB3,PRKAR1B,GDI1,IMPDH2,PPP1R7,ATP6V1E1,TUBB4B,IPO4,GAPDH,PFKL,FKBP1A,VPS4B,LARS,NEDD4L,GART,NAP1L1,SEC31A,APRT,GMPPB,CDK6,PFKP,HSPA6,MAP2K2,UGP2,PEBP1,SHMT1,GMPR2,CTPS1,XPNPEP1,UBA1,AHCY,IPO5,EEF2,TAGLN2,ISYNA1,GSPT1,PDIA3,NAP1L4,TUBA4A,HSPH1,NUTF2,HSPA4,SDSL,GDI2,TSR1,DSTN,DYNC1H1,NPEPPS,PSMD11,IPO7,ALDOA,HSP90AA1,POLR3B,CAD,RRM2,CCT8,ABCE1,PYGB,STIP1,ATF2,EIF4A1,ACTB,ACACA,PPID,PRDX2,HINT1,EIF4A2,HMGCS1,HSP90AB1,OLA1,CCT7,PKM,PPIA,PPP2CB,KRI1,TP53RK,CCT4,PSMD7,NSFL1C,CCT3,CTPS2,EIF2S2,HSPA1B,MAPK1,GPN1,CSNK1D,TKT,HDAC6,PPP6C,COPA,GMPR,IMPDH1,ARHGAP1,TUBA1A,BTF3L4,PSMB2,PPAN,FARSA,ATE1,GSPT2,TUBB6,VCP,MPI,TUBB,MAT2A,EIF3B,GPI,MOB1B,SLC27A1,XPO1,ETF1,MCM2,PSMC3,ABCF1,SAR1A,FBXO21,CLUH,IDE,EIF2S3,PSMB3,TUBB4A,SEC23B,PRDX5,DDX52,ACTR2" -1.988121643 -0.412854407 151 464 DRUG METABOLISM - CYTOCHROME P450 DRUG METABOLISM - CYTOCHROME P450 0.000117523 0.000264869 -1 "PGRMC2,SARS,MAP1LC3A,AARS,GFPT1,APP,F10,GARS,XPOT,CTH,PDIA4,TARS,SNX2,PDCD6IP,GALT,HSPA5,ATIC,TNIP1,ACY1,ENO2,SLC3A2,GOT1,ATP6V1A,ATP6V1B2,MTHFD1,RPS6KA3,NARS,PRKAR1A,ATP6V1C1,PGD,PFKM,TUBB3,PRKAR1B,GDI1,EIF2A,NDRG1,ATP6V1E1,TUBB4B,IPO4,GAPDH,PRDX1,GSTM3,PFKL,IKBKB,PRDX6,FKBP1A,LARS,TGM2,NAP1L1,BLMH,ACSS2,PDXDC1,BCAT1,AHSA1,GSTO1,AKR1A1,GMPPB,RAB3GAP1,PFKP,HSPA6,PGM1,MAP2K2,BAG3,UGP2,GSTM1,EIF4EBP1,HARS,SHMT1,IARS,CTPS1,ARFGAP1,PPA1,MYO1E,PSME1,UBA1,AHCY,EEF2,ISYNA1,PDIA3,NAP1L4,PRKAA2,TUBA4A,PYCRL,HSPH1,NUTF2,HSPA4,SDSL,GDI2,NAA15,DSTN,NAA50,GSTCD,DBNL,PTPN11,EIF2B2,ISG15,NPEPPS,PSMD11,ENO1,CCT5,HSP90AA1,POLR3B,DCTN1,CAD,HNRNPM,ARRB2,MYH10,RRM2,DERA,EIF2B5,CCT8,UGDH,PYGB,STIP1,EPS8L2,ATF2,EIF4A1,GSTP1,PCBP1,DARS,ACTB,ACACA,ACAT2,ALDH3B1,PPID,YWHAZ,EGFR,CAND1,PRDX2,STAT1,SH3GLB1,EIF4A2,ADK,MLLT4,ARL1,HMGCS1,HSP90AB1,SLC1A5,UBE2O,ARMT1,OLA1,XPO7,TPP2,TSC22D3,LSM1,CCT7,SNX3,PKM,MMS19,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,DVL2,CCT4,YWHAG,ALDH16A1,PSMD7,CCT3,TALDO1,CTPS2,EIF2S2,PLS3,HSPA1B,PAAF1,MAPK1,ATG5,GPN1,PSMF1,CAB39,ATP6V1D,TCP1,RAB3GAP2,MYL1,GNB1L,TKT,SETD1B,PPP6C,COPA,TNPO2,PLS1,CSE1L,PIP4K2A,TUBA1A,BTF3L4,OGFR,DTD1,PSMD6,MYH9,FARSA,COPS5,LCN2,UBE3C,ARF4,TUBB6,VCP,ARRB1,MPI,TUBB,LSM3,MAT2A,TRAF2,GPI,MOB1B,ETF1,MCM2,PSMC3,EIF5B,IQGAP1,TCEA1,CLUH,PPP3CB,EXOC6,PRMT5,EIF2S3,XPO5,SBDS,TUBB4A,SEC23B,VHL,PRDX5,ASL,ACTR2,ATXN10,EIF2B3,EIF4EBP2,UFL1" -1.750803227 -0.353245593 228 719 VITAMIN B9 (FOLATE) METABOLISM VITAMIN B9 (FOLATE) METABOLISM 0.000121168 0.000264869 -1 "MAP1LC3A,AARS,GFPT1,APP,GARS,YARS,HSPA5,ATIC,ENO2,POC5,GOT1,SNX8,ATP6V1A,ATP6V1B2,MTHFD1,COPRS,NARS,PGD,PFKM,HUWE1,TUBB3,NDRG1,ATP6V1E1,TUBB4B,GAPDH,CASP4,PFKL,FKBP1A,LARS,NEDD4L,GART,NAP1L1,ACSS2,SEC31A,GMPPB,SCRIB,PFKP,HSPA6,PGM1,UGP2,ADSL,SHMT1,IARS,CTPS1,ALDOC,PPA1,MYO1E,AHCY,ACO1,EEF2,BCL2L11,ISYNA1,ELP4,NAP1L4,TUBA4A,HSPH1,NUTF2,HSPA4,NTN4,NPEPPS,CCT5,HSP90AA1,POLR3B,CAD,HNRNPM,CCT8,BIN1,UGDH,ZNFX1,PYGB,MTHFR,LIN9,ATF2,STK10,EIF4A1,HGS,TRERF1,ACTB,ACACA,ACAT2,YWHAZ,HLA-B,PRDX2,HEBP2,EIF4A2,HSP90AB1,UBR4,BABAM1,PIN4,RNASEH2A,LSM1,CCT7,MMS19,YWHAQ,KANK1,ABCF3,SDF2L1,PPIA,KRI1,COPB1,HECW2,CCT4,EIF6,CCT3,TALDO1,CTPS2,IFNGR1,TNFRSF10D,HSPA1B,MAPK1,CAPZA2,IL18,TCP1,S100A11,CSNK1D,HDAC6,ILK,FBXO6,PSMB1,COPA,CSE1L,UBA5,FUNDC2,TUBA1A,TTC39C,PSMB2,PSMD6,FNBP1,COPS5,ARF4,TUBB6,VCP,TUBB,MAT2A,RAPGEF6,GPI,XPO1,EXOC2,MCM2,PSMC3,EIF5B,SSH3,PDCL3,TUBGCP3,CLUH,PRUNE,SUGT1,PARG,EIF2S3,KIAA1217,TUBB4A,NT5C3B,PXN,PSMA1,ASL,ACTR2" -1.489407149 -0.305153558 156 554 TRYPTOPHAN METABOLISM TRYPTOPHAN METABOLISM 0.000111445 0.000264869 -1 "PGRMC2,SDCBP,SARS,MAP1LC3A,AARS,GFPT1,TBC1D15,APP,F10,GARS,XPOT,CTH,PDIA4,TARS,LGALS3BP,GYS1,SNX2,PDCD6IP,ASS1,GALT,HSPA5,ATIC,ABL2,TNIP1,ACY1,ENO2,SLC3A2,GALE,WARS,GOT1,ATP6V1A,CNDP2,ATP6V1B2,MTHFD1,RPS6KA3,NARS,PRKAR1A,ATP6V1C1,PGD,PFKM,HUWE1,TUBB3,PRKAR1B,GDI1,EIF2A,IMPDH2,PPP1R7,NDRG1,ATP6V1E1,TUBB4B,IPO4,GAPDH,PRDX1,GSTM3,PFKL,IKBKB,IFRD2,PRDX6,FKBP1A,LARS,NEDD4L,TGM2,GART,NAP1L1,BLMH,ACSS2,PDXDC1,BCAT1,APRT,AHSA1,GSTO1,AKR1A1,GMPPB,PLIN3,RAB3GAP1,PFKP,HSPA6,PGM1,MAP2K2,BAG3,UGP2,GSTM1,SHMT1,IARS,KEAP1,CTPS1,ARFGAP1,PPA1,SRM,MYO1E,ABHD14B,PSME1,UBA1,TIMP2,NDOR1,AHCY,IPO5,EEF2,ISYNA1,PDIA3,NAP1L4,PRKAA2,TUBA4A,PPP2R4,PYCRL,HSPH1,PARK7,NUTF2,HSPA4,SDSL,GDI2,GTPBP2,KIF5B,NAA15,TSR1,DSTN,NAA50,GSTCD,RIN1,DBNL,PTPN11,PTGES3,EIF2B2,ISG15,NPEPPS,PSMD11,MARS,ENO1,ALDOA,PRKCI,CCT5,HSP90AA1,TRIP13,POLR3B,DCTN1,CAD,HNRNPM,MYH10,RRM2,DERA,EIF2B5,CCT8,ABCE1,PYGB,STIP1,EPS8L2,ATF2,EIF4A1,PPP2R5D,GSTP1,TNIK,PCBP1,DARS,ACTB,ACACA,ACAT2,PPID,YWHAZ,EGFR,HLA-B,PLAA,FHIT,CAND1,PRDX2,STAT1,SH3GLB1,EIF4A2,ADK,MLLT4,ARL1,HMGCS1,TXN,HSP90AB1,SLC1A5,UBE2O,TSC2,ARMT1,OLA1,VAC14,XPO7,DDI2,IPO13,TPP2,LSM1,CCT7,SNX3,PKM,MMS19,YWHAQ,ATXN3,CKS1B,VBP1,SDF2L1,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,GCLC,DVL2,WIPI2,NFKB1,ARHGDIA,CCT4,YWHAG,ALDH16A1,EIF6,PSMD7,SLC35F6,CLDN12,NSFL1C,CCT3,KPNB1,TALDO1,CTPS2,CLK1,EIF2S2,METAP1,PLS3,HSPA1B,PAAF1,MAPK1,CAPZA2,ATG5,DRG2,GPN1,PSMF1,CAB39,ATP6V1D,TRAPPC8,THADA,TCP1,RAB3GAP2,MYL1,CSNK1D,GNB1L,TKT,NOM1,FBXO6,SETD1B,FERMT2,PPP6C,COPA,TNPO2,PLS1,CSE1L,IMPDH1,UBA5,PIP4K2A,TUBA1A,BTF3L4,OGFR,DTD1,PSMD6,MYH9,PPAN,FARSA,COPS5,UBE3C,RAD23B,ARF4,TUBB6,VCP,ARRB1,MPI,TUBB,LSM3,MAT2A,TRAF2,RMND5A,GPI,MOB1B,XPO1,ETF1,MCM2,PSMC3,EIF5B,SAR1A,IQGAP1,BAG6,PPP2R5B,TCEA1,CLUH,RELA,IDE,PPP3CB,EXOC6,MAP3K7,FTSJ1,PRMT5,PRUNE,AKT1,EIF2S3,XPO5,SBDS,TUBB4A,BUB1,SEC23B,VHL,PRDX5,TRAF4,PSMA1,ASL" -1.663888634 -0.329184749 303 1055 DE NOVO FATTY ACID BIOSYNTHESIS DE NOVO FATTY ACID BIOSYNTHESIS 0.000123411 0.000264869 -1 "SARS,AARS,GFPT1,APP,GARS,CTH,PDIA4,TARS,GALT,HSPA5,ATIC,ENO2,GOT1,ATP6V1A,ATP6V1B2,MTHFD1,NARS,PRKAR1A,ATP6V1C1,PGD,PFKM,TPI1,TUBB3,PRKAR1B,GDI1,ATP6V1E1,TUBB4B,PSMD9,IPO4,GAPDH,PFKL,FKBP1A,LARS,NEDD4L,GART,ACSS2,BCAT1,SRRM2,AKR1A1,GMPPB,PFKP,HSPA6,PGM1,UGP2,ADSL,SHMT1,IARS,FASN,CTPS1,PPA1,UBA1,AHCY,EEF2,EPRS,PDIA3,TUBA4A,HSPH1,NUTF2,HSPA4,GDI2,TSR1,DSTN,NPEPPS,PSMD11,MARS,ENO1,ALDOA,CCT5,HSP90AA1,POLR3B,CAD,AASDHPPT,RRM2,CCT8,DNM1L,PYGB,EIF4A1,DARS,ACTB,ACACA,ACAT2,YWHAZ,EGFR,HLA-B,PRDX2,EIF4A2,ADK,HMGCS1,HSP90AB1,BABAM1,OLA1,CCT7,MMS19,YWHAQ,PPIA,AKR1D1,KRI1,HECW2,CCT4,YWHAG,EIF6,ABCG1,CCT3,KPNB1,TALDO1,CTPS2,PLS3,HSPA1B,MAPK1,ATG5,CARHSP1,UBQLN1,MYL1,CSNK1D,TKT,FBXO6,CHMP3,PPP6C,TNPO2,PLS1,CSE1L,TUBA1A,BTF3L4,CDC37,MYH9,FARSA,ARF4,TUBB6,VCP,MPI,TUBB,RAB6C,MAT2A,TRAF2,GPI,XPO1" -1.648327249 -0.340333575 136 497 VITAMIN A (RETINOL) METABOLISM VITAMIN A (RETINOL) METABOLISM 0.000118147 0.000264869 -1 "PGRMC2,SARS,MAP1LC3A,AARS,GFPT1,APP,GARS,XPOT,CTH,PDIA4,TARS,GYS1,SNX2,ASS1,GALT,HSPA5,ATIC,ENO2,GOT1,ATP6V1A,CNDP2,ATP6V1B2,MTHFD1,NARS,PRKAR1A,ATP6V1C1,PGD,PFKM,TUBB3,PRKAR1B,GDI1,EIF2A,IMPDH2,PPP1R7,ATP6V1E1,TUBB4B,PSMD9,IPO4,GAPDH,PFKL,FKBP1A,LARS,NEDD4L,GART,NAP1L1,BLMH,ACSS2,BCAT1,SRRM2,AKR1A1,GMPPB,PFKP,HSPA6,PGM1,MAP2K2,UGP2,EIF4EBP1,ADSL,HARS,SHMT1,IARS,CTPS1,PPA1,SRM,MYO1E,PSME1,UBA1,AHCY,IPO5,EEF2,ISYNA1,PDIA3,NAP1L4,PRKAA2,TUBA4A,PYCRL,HSPH1,NUTF2,HSPA4,SDSL,GDI2,NAA15,TSR1,DSTN,NAA50,DBNL,PTPN11,EIF2B2,NPEPPS,PSMD11,MARS,ENO1,ALDOA,CCT5,HSP90AA1,POLR3B,CAD,ARRB2,MYH10,RRM2,EIF2B5,CCT8,DNM1L,UGDH,PYGB,STIP1,ATF2,EIF4A1,DARS,ACTB,ACACA,ACAT2,PPID,YWHAZ,PRDX2,EIF4A2,ADK,MLLT4,HMGCS1,HSP90AB1,OLA1,TPP2,SPINT2,LSM1,CCT7,SNX3,PKM,MMS19,YWHAQ,CKS1B,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,GCLC,HECW2,CCT4,YWHAG,EIF6,PSMD7,ABCG1,NSFL1C,CCT3,KPNB1,TALDO1,CTPS2,EIF2S2,PLS3,HSPA1B,PAAF1,MAPK1,ATG5,DRG2,GPN1,PSMF1,CAB39,ATP6V1D,TCP1,MYL1,CSNK1D,TKT,NOM1,SETD1B,PPP6C,COPA,TNPO2,PLS1,CSE1L,IMPDH1,TUBA1A,BTF3L4,DTD1,PSMD6,MYH9,PPAN,FARSA,LCN2,UBE3C,ARF4,TUBB6,VCP,ARRB1,MPI,TUBB,RAB6C,MAT2A,GPI,MOB1B,XPO1,ETF1,MCM2,PSMC3,EIF5B,SAR1A,IQGAP1,TCEA1,CLUH,IDE,PPP3CB,EXOC6,PRMT5,PRUNE" -1.705857168 -0.344853377 203 696 "VALINE, LEUCINE AND ISOLEUCINE DEGRADATION" "VALINE, LEUCINE AND ISOLEUCINE DEGRADATION" 0.000110717 0.000264869 -1 "RPTOR,SDCBP,SARS,MAP1LC3A,SQSTM1,AARS,HSPB1,GFPT1,TBC1D15,APP,GARS,XPOT,CTH,LAMP1,PDIA4,TARS,LGALS3BP,GYS1,ASS1,RRAGA,GALT,HSPA5,ATIC,ENO2,POC5,GALE,GOT1,CALCOCO2,ATP6V1A,CNDP2,ATP6V1B2,MTHFD1,ASNS,IDH1,NARS,PRKAR1A,ATP6V1C1,PGD,PFKM,PGK1,HUWE1,TPI1,TUBB3,PRKAR1B,GDI1,IMPDH2,PPP1R7,ATP6V1E1,TUBB4B,IPO4,GAPDH,PFKL,IFRD2,FKBP1A,LARS,NEDD4L,GART,NAP1L1,ACSS2,BCAT1,APRT,GSTO1,SRRM2,AKR1A1,GMPPB,RAB3GAP1,PFKP,HSPA6,PGM1,MAP2K2,BAG3,UGP2,NFKBIE,PEBP1,SHMT1,IARS,GMPR2,CTPS1,PPA1,SRM,MYO1E,XPNPEP1,ABHD14B,UBA1,TIMP2,ARMC6,RRAGC,AHCY,CUL4B,IPO5,EEF2,TAGLN2,ISYNA1,EPRS,PDIA3,NAP1L4,KLC4,PRKAA2,TUBA4A,PYCRL,HSPH1,PARK7,NUTF2,HSPA4,SDSL,GDI2,GTPBP2,TSR1,DSTN,OTUD5,PTGES3,EIF2B2,ISG15,NPEPPS,PSMD11,MARS,PAPSS1,ENO1,ALDOA,PRKCI,CCT5,HSP90AA1,POLR3B,CAD,PUS7,MYH10,RRM2,EIF2B5,CCT8,ABCE1,PYGB,STIP1,ATF2,UBQLN2,EIF4A1,PPP2R5D,TNIK,DARS,ACTB,ACACA,ACAT2,PPID,YWHAZ,EGFR,HLA-B,PLAA,FHIT,CALR,CAND1,PRDX2,NOTCH2,STAT1,HINT1,EIF4A2,USP5,ADK,HMGCS1,HSP90AB1,TSC2,OLA1,IPO13,ECHDC1,RNASEH2A,LSM1,CCT7,PKM,MSN,VCL,MMS19,YWHAQ,NFKBIB,CKS1B,ABCF3,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,GCLC,DVL2,NFKB1,TP53RK,CCT4,EIF6,PSMD7,SLC35F6,RARS,SHC1,CLDN12,NSFL1C,CCT3,KPNB1,TALDO1,CTPS2,CLK1,EIF2S2,METAP1,PLS3,TNFRSF10D,MAP3K3,HSPA1B,PAAF1,MAPK1,CAPZA2,ATG5,DRG2,GPN1,ASNA1,PPT1,ATP6V1D,TRAPPC8,UBQLN1,THADA,HELZ,TCP1,MYL1,CSNK1D,NOTCH3,TKT,NOM1,HDAC6,SH3KBP1,FBXO6,SETD1B,FERMT2,PPP6C,COPA,EEF1E1,GMPR,EPS15,UGGT1,TNPO2,PLS1,CSE1L,IMPDH1,UBA5,DNAJC21,TUBA1A,BTF3L4,BCAR3,PSMB2,PSMD6,PFDN4,MYH9,PPAN,IKBKG,UMPS,FBXO7,FNBP1,FARSA,COPS5,ATE1,UBE3C,ARF4,TUBB6,VCP,MPI,AIMP1,TUBB,LAMP2,MAT2A,GPI,MOB1B,XPO1,ETF1,MCM2,USP16,PSMC3,EIF5B,ABCF1,SAR1A,MRM1,FBXO21,BAG6,CLUH,RELA,IDE,PPP3CB,MAP3K7,INPPL1,FTSJ1,PRMT5,PRUNE,AKT1,PARG,EIF2S3,PSMB3,MMAA,TANK,PER1,TUBB4A,BUB1,PXN,SEC23B,VHL,PRDX5,TRAF4,ASL,DDX52,ACTR2" -1.557632009 -0.30749564 300 1115 FATTY ACID METABOLISM FATTY ACID METABOLISM 0.000112841 0.000264869 -1 "PGRMC2,SARS,MAP1LC3A,SQSTM1,AARS,GFPT1,TBC1D15,APP,GARS,XPOT,CTH,LAMP1,PDIA4,TARS,LGALS3BP,GYS1,SNX2,ASS1,RRAGA,GALT,HSPA5,ATIC,TNIP1,ENO2,GALE,GOT1,RNF31,CALCOCO2,ATP6V1A,CNDP2,ATP6V1B2,MTHFD1,RPS6KA3,NARS,PRKAR1A,ATP6V1C1,ABHD5,PAICS,PGD,PFKM,PGK1,HUWE1,PDIA6,UBE2V1,TUBB3,NDUFA4,PRKAR1B,GDI1,EIF2A,IMPDH2,PPP1R7,NDRG1,ATP6V1E1,TUBB4B,IPO4,GAPDH,PRDX1,PFKL,FKBP1A,LARS,NEDD4L,GART,NAP1L1,BLMH,ACSS2,BCAT1,SEC31A,GSTO1,AKR1A1,GMPPB,CDK6,PFKP,HSPA6,PGM1,MAP2K2,APOC3,BAG3,UGP2,SHMT1,IARS,FASN,CTPS1,PSEN2,PPA1,SRM,MYO1E,SPG20,PSME1,UBA1,ARMC6,AHCY,MAPRE1,IPO5,EEF2,ISYNA1,PDIA3,NAP1L4,PRKAA2,VTA1,TUBA4A,PYCRL,HSP90B1,HSPH1,NUTF2,HSPA4,SDSL,GDI2,NAA15,TSR1,DSTN,NAA50,DBNL,MRPS17,PTPN11,EIF2B2,NPEPPS,PSMD11,MARS,IPO7,DYRK1A,ENO1,ALDOA,PRKCI,CCT5,HSP90AA1,POLR3B,CAD,MYH10,RRM2,EIF2B5,CCT8,PYGB,STIP1,ATF2,EIF4A1,UBE2R2,DARS,ACTB,ACACA,ACAT2,PPID,YWHAZ,EGFR,PLAA,FHIT,CALR,CAND1,PRDX2,CDK5,HINT1,EIF4A2,ADK,MLLT4,HMGCS1,HSP90AB1,SLC1A5,TSC2,OLA1,IPO13,TPP2,LSM1,CCT7,SNX3,PKM,MSN,VCL,MMS19,YWHAQ,CNPY2,NT5C2,CKS1B,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,GCLC,HECW2,CCT4,EIF6,PSMD7,ABCG1,SLC35F6,NSFL1C,CCT3,DDX3X,KPNB1,TALDO1,CTPS2,BRAF,LRSAM1,EIF2S2,PLS3,HSPA1B,PAAF1,MAPK1,CAPZA2,DRG2,GPN1,PSMF1,CAB39,ATP6V1D,THADA,APOB,TCP1,MYL1,CSNK1D,TKT,NOM1,FBXO6,ARFGEF2,SETD1B,CHMP3,PPP6C,COPA,UGGT1,TNPO2,PLS1,CSE1L,IMPDH1,UBA5,ARHGAP1,TUBA1A,BTF3L4,DTD1,PNPLA2,PSMD6,PFDN4,MYH9,PPAN,FARSA,COPS5,UBE3C,ARF4,TUBB6,VCP,ARRB1,MPI,TUBB,GET4,LAMP2,MAT2A,WASL,GPI,MOB1B,SLC27A1,XPO1,ETF1,NUDCD3,MCM2,PSMC3,EIF5B,MPZL1,TUBGCP3,IQGAP1,TCEA1,CLUH,IDE,PPP3CB,RABAC1,EXOC6,EXOC1,PRMT5,PRUNE" -1.597960588 -0.317418611 264 977 FRUCTOSE AND MANNOSE METABOLISM FRUCTOSE AND MANNOSE METABOLISM 0.000111495 0.000264869 -1 "RPTOR,SARS,MAP1LC3A,AARS,GFPT1,APP,GARS,XPOT,CTH,PSAT1,PDIA4,TARS,GYS1,ASS1,RRAGA,GALT,HSPA5,ATIC,ENO2,GOT1,ATP6V1A,CNDP2,ATP6V1B2,TSTA3,MTHFD1,ASNS,IDH1,NARS,PRKAR1A,ATP6V1C1,PGD,PFKM,PGK1,HUWE1,ATOX1,TUBB3,NDUFA4,PRKAR1B,GDI1,IMPDH2,PPP1R7,ATP6V1E1,TUBB4B,PSMD9,IPO4,GAPDH,PRDX1,PFKL,IKBKB,FKBP1A,VPS4B,LARS,NEDD4L,GART,NAP1L1,BLMH,ACSS2,LDHB,BCAT1,HGH1,APRT,BAD,AHSA1,GSTO1,SRRM2,CCS,AKR1A1,GMPPB,PFKP,HSPA6,PGM1,SORD,MAP2K2,BAG3,UGP2,EIF4EBP1,ADSL,SHMT1,IARS,PRPS2,CTPS1,ALDOC,PPA1,SRM,MYO1E,UBA1,MDP1,AHCY,CUL4B,IPO5,NADSYN1,EEF2,ISYNA1,GSPT1,PDIA3,NAP1L4,PRKAA2,TUBA4A,PYCRL,HSPH1,NUTF2,HSPA4,SDSL,GDI2,SGTA,NIF3L1,NAA15,TSR1,DSTN,GSK3A,PTGES3,EIF2B2,ISG15,NPEPPS,PSMD11,MARS,IPO7,ENO1,UBE2M,ALDOA,PRKCI,CCT5,HSP90AA1,POLR3B,CAD,MVK,ARRB2,FBP1,RRM2,EIF2B5,CCT8,DNM1L,NUP62,BIN1,PYGB,STIP1,PPME1,POTEE,ATF2,ARPC4,EIF4A1,PPP2R5D,ESD,TNIK,DARS,ACTB,ACACA,ACAT2,PPID,YWHAZ,EGFR,WDR1,HLA-B,CALR,PRDX2,NOTCH2,HINT1,EIF4A2,LDHA,USP5,ADK,HMGCS1,ARPC3,TXN,HSP90AB1,LTA4H,CKB,OLA1,PSMB6,DDI2,PSMB8,LSM1,CCT7,PKM,FN3K,MSN,AKR1B1,MMS19,YWHAQ,PTK2,CKS1B,ABCF3,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,GCLC,ABCC3,AKR7A2,NFKB1,GMDS,ARHGDIA,HECW2,TP53RK,FAT1,CCT4,YWHAG,EIF6,PSMD7,NSFL1C,CCT3,PEA15,KPNB1,PSMA2,BMPR1A,TALDO1,IST1,CTPS2,BRAF,EIF2S2,PLS3,AKR1C3,IRF3,GBE1,HSPA1B,PAAF1,MAPK1,ATG5,CARHSP1,GPN1,GLO1,ATP6V1D,UBQLN1,TCP1,MYL1,CSNK1D,PFKFB2,NOTCH3,TKT,NOM1,KPNA3,HDAC6,ILK,PNPO,FBXO6,ARFGEF2,PSMB1,PPP6C,COPA,TNPO2,PLS1,CSE1L,IMPDH1,DNAJC21,NDUFB8,TUBA1A,BTF3L4,PSMB2,PSMD6,PFDN4,SNX9,MYH9,PPAN,FARSA,COPS5,GSPT2,UBE3C,MAP2K3,RAD23B,ARF4,TUBB6,VCP,ARRB1,MPI,TUBB,PSMA7,VPS4A,MAT2A,ARPC5,WASL,TMEM55A,GPI,MOB1B,XPO1,ETF1,FN3KRP,MCM2,KDELR3,PSMC3,EIF5B,ABCF1,SAR1A,PPP2R5B,NDUFB1,CLUH,RELA,PPP3CB,MAP3K7,PRMT5,PRUNE,AKT1,RPS14,ARPC2,CCDC22,AP3D1,EIF2S3,ATP5J2,PSMB3,XPO5,TUBB4A,BUB1,SEC23B,VHL,PRDX5,PSMA1,ASL,PSMA5,ACTR2,PSMB9,EIF2B3,EIF4EBP2,FLCN" -1.687801305 -0.334003649 313 1048 ROS DETOXIFICATION ROS DETOXIFICATION 0.000128041 0.000264869 -1 "SARS,SQSTM1,AARS,GFPT1,APP,GARS,CTH,PDIA4,TARS,GYS1,GALT,HSPA5,ATIC,ABL2,ENO2,GOT1,ATP6V1A,ATP6V1B2,MTHFD1,NARS,PRKAR1A,ATP6V1C1,PGD,OPTN,PFKM,TUBB3,PRKAR1B,GDI1,ATP6V1E1,TUBB4B,IPO4,GAPDH,PFKL,FKBP1A,NEDD4L,NAP1L1,ACSS2,BCAT1,APRT,CCS,AKR1A1,GMPPB,TMEM131,PFKP,HEATR6,HSPA6,PGM1,UGP2,IARS,KEAP1,PPA1,MYO1E,UBA1,AHCY,EEF2,PDIA3,NAP1L4,TUBA4A,HSP90B1,HSPH1,PARK7,NUTF2,HSPA4,SDSL,GDI2,SGTA,DSTN,PTPN11,SCRN1,EIF2B2,NPEPPS,FYN,ENO1,ALDOA,CCT5,HSP90AA1,DCTN1,CAD,WWP2,RRM2,CCT8,USP9X,PYGB,STIP1,EIF4A1,TNIK,DARS,ACTB,ACACA,ACAT2,HLA-B,CALR,PRDX2,HINT1,EIF4A2,ADK,PPP1R12A,HMGCS1,TXN,HSP90AB1,KLC2,OLA1,DDI2,COMMD1,PKM,AKR1B1,SDF2L1,PPIA,PPP2CB,AKR1D1,ABCC3,NFKB1,CCT4,YWHAG,CCT3,KPNB1,STUB1,PLS3,HSPA1B,MAPK1,TCP1,MYL1,CSNK1D,TKT,RNF19A,HDAC6,PNPO,SOD3,COPA,PLS1,CSE1L,TUBA1A,BTF3L4,PSMB2,FARSA,UBE3C,RAD23B,TUBB6,ZPR1,VCP,MPI,TUBB,GET4,MAT2A,GPI,XPO1,MCM2,IQGAP1,CLUH,PPP3CB,MAP3K7,FTSJ1,PRMT5,EIF2S3,PSMB3,TUBB4A,VHL,PRDX5,PSMA1" -2.118171546 -0.44588595 159 394 XENOBIOTICS METABOLISM XENOBIOTICS METABOLISM 0.00011711 0.000264869 -1 "PGRMC2,SARS,MAP1LC3A,AARS,GFPT1,APP,F10,GARS,XPOT,CTH,PDIA4,TARS,SNX2,PDCD6IP,NDST1,GALT,HSPA5,ATIC,TNIP1,ACY1,ENO2,SLC3A2,GOT1,CALCOCO2,ATP6V1A,ATP6V1B2,MTHFD1,RPS6KA3,NARS,PRKAR1A,ATP6V1C1,PGD,PFKM,TUBB3,PRKAR1B,GDI1,EIF2A,ATP6V1E1,TUBB4B,IPO4,GAPDH,PRDX1,GSTM3,PFKL,IKBKB,PRDX6,FKBP1A,LARS,TGM2,NAP1L1,BLMH,ACSS2,PDXDC1,BCAT1,AHSA1,GSTO1,AKR1A1,GMPPB,RAB3GAP1,PFKP,HSPA6,PGM1,MAP2K2,BAG3,UGP2,GSTM1,EIF4EBP1,HARS,SHMT1,IARS,CTPS1,ARFGAP1,PPA1,MYO1E,PSME1,UBA1,AHCY,EEF2,ISYNA1,PDIA3,NAP1L4,PRKAA2,TUBA4A,PYCRL,HSPH1,NUTF2,HSPA4,SDSL,GDI2,NIF3L1,NAA15,DSTN,NAA50,GSTCD,DBNL,PTPN11,EIF2B2,ISG15,NPEPPS,PSMD11,ENO1,CCT5,HSP90AA1,POLR3B,DCTN1,CAD,HNRNPM,ARRB2,MYH10,RRM2,DERA,EIF2B5,CCT8,UGDH,PYGB,STIP1,EPS8L2,ATF2,EIF4A1,GSTP1,PCBP1,DARS,ACTB,ACACA,ACAT2,ALDH3B1,PPID,YWHAZ,EGFR,CAND1,PRDX2,STAT1,SH3GLB1,EIF4A2,ADK,MLLT4,ARL1,HMGCS1,HSP90AB1,SLC1A5,UBE2O,ARMT1,OLA1,XPO7,TPP2,TSC22D3,SPINT2,LSM1,CCT7,SNX3,PKM,MMS19,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,DVL2,CCT4,YWHAG,ALDH16A1,PSMD7,CCT3,TALDO1,CTPS2,EIF2S2,PLS3,HSPA1B,PAAF1,MAPK1,ATG5,GPN1,PSMF1,CAB39,ATP6V1D,TCP1,RAB3GAP2,MYL1,GNB1L,TKT,SETD1B,PPP6C,COPA,TNPO2,PLS1,CSE1L,PIP4K2A,TUBA1A,CHST11,BTF3L4,OGFR,DTD1,PSMD6,MYH9,FARSA,COPS5,LCN2,UBE3C,ARF4,TUBB6,VCP,ARRB1,MPI" -1.7347039 -0.349484448 203 738 SATURATED FATTY ACIDS BETA-OXIDATION SATURATED FATTY ACIDS BETA-OXIDATION 0.000124316 0.000264869 -1 "MAP1LC3A,SQSTM1,AARS,GFPT1,APP,GARS,CTH,LAMP1,PDIA4,GALT,HSPA5,ATIC,TNIP1,ACY1,ENO2,GOT1,CNDP2,ATP6V1B2,MTHFD1,NARS,PGD,PFKM,HUWE1,UBE2V1,NDUFA4,GDI1,GAPDH,PRDX1,PFKL,IFRD2,LARS,ACSS2,BCAT1,GSTO1,AKR1A1,CDK6,PFKP,HSPA6,VPS28,PGM1,BAG3,UGP2,SHMT1,IARS,PPA1,ABHD14B,UBA1,TIMP2,ARMC6,AHCY,EEF2,ISYNA1,RIC8A,PDIA3,PRKAA2,VTA1,HSPH1,PARK7,HSPA4,GDI2,GTPBP2,MRPS17,CLN3,PTGES3,NPEPPS,DYRK1A,ENO1,CLIC1,ALDOA,HSP90AA1,CCT8,ABCE1,PYGB,STIP1,ATF2,EIF4A1,TNIK,DARS,ACTB,ACAT2,PPID,YWHAZ,EGFR,HLA-B,CALR,PRDX2,STAT1,CDK5,HINT1,EIF4A2,ADK,HSP90AB1,OLA1,MSN,VCL,YWHAQ,CKS1B,PPIA,AKR1D1,MAP1B,CLDN12,DDX3X,KPNB1,CLK1,MCL1,PLS3,HSPA1B,MAPK1,ATG5,CARHSP1,PPT1,TRAPPC8,UBQLN1,CSNK1D,TKT,HDAC6,FBXO6,FERMT2,PLS1,UBA5" -1.669047468 -0.346111095 120 472 OMEGA-3 FATTY ACID METABOLISM OMEGA-3 FATTY ACID METABOLISM 0.00011711 0.000264869 -1 "PGRMC2,SARS,MAP1LC3A,SQSTM1,AARS,GFPT1,APP,GARS,XPOT,CTH,LAMP1,PDIA4,TARS,RRAGA,GALT,HSPA5,ATIC,ENO2,GOT1,CALCOCO2,ATP6V1A,ATP6V1B2,MTHFD1,NARS,PRKAR1A,ATP6V1C1,PAICS,PGD,PFKM,HUWE1,UBE2V1,TUBB3,NDUFA4,PRKAR1B,GDI1,NDRG1,ATP6V1E1,TUBB4B,PSMD9,IPO4,GAPDH,PFKL,IFRD2,FKBP1A,LARS,NEDD4L,GART,ACSS2,BCAT1,GSTO1,SRRM2,AKR1A1,GMPPB,CDK6,PFKP,HSPA6,PGM1,UGP2,ADSL,SHMT1,IARS,CTPS1,PPA1,SPG20,ABHD14B,UBA1,TIMP2,ARMC6,AHCY,EEF2,ISYNA1,EPRS,PDIA3,PRKAA2,VTA1,TUBA4A,PYCRL,HSPH1,PARK7,NUTF2,HSPA4,SDSL,GDI2,GTPBP2,TSR1,DSTN,MRPS17,CLN3,PTGES3,EIF2B2,NPEPPS,PSMD11,MARS,IPO7,DYRK1A,ENO1,ALDOA,CCT5,HSP90AA1,POLR3B,CAD,RRM2,EIF2B5,CCT8,DNM1L,PYGB,STIP1,ATF2,EIF4A1,TNIK,DARS,ACTB,ACACA,ACAT2,PPID,YWHAZ,EGFR,HLA-B,CALR,PRDX2,STAT1,CDK5,HINT1,EIF4A2,ADK,HMGCS1,HSP90AB1,SLC1A5,OLA1,CCT7,MSN,VCL,MMS19,YWHAQ,NT5C2,PPIA,AKR1D1,KRI1,HECW2,CCT4,YWHAG,EIF6,PSMD7,ABCG1,CLDN12,CCT3,DDX3X,KPNB1,TALDO1,CTPS2,CLK1,EIF2S2,PLS3,HSPA1B,MAPK1,ATG5,GPN1,ATP6V1D,MYL1,CSNK1D,TKT,NOM1,FBXO6,FERMT2,PPP6C,TNPO2,PLS1,CSE1L,UBA5,TUBA1A,BTF3L4,CDC37,PFDN4,MYH9,FARSA,COPS5,ARF4,TUBB6,VCP,MPI,TUBB,RAB6C,GET4,LAMP2,MAT2A,WASL,GPI,MOB1B,SLC27A1,XPO1,MCM2,PSMC3,SAR1A,TUBGCP3,BAG6,CLUH,PPP3CB,RABAC1,EXOC1,FTSJ1,PRMT5,EIF2S3,TUBB4A,UBE2D2,SEC23B,VHL,PRDX5" -1.579152275 -0.318146031 207 738 BUTANOATE METABOLISM BUTANOATE METABOLISM 0.000115022 0.000264869 -1 "SARS,MAP1LC3A,SQSTM1,AARS,GFPT1,TBC1D15,APP,GARS,XPOT,CTH,PDIA4,TARS,LGALS3BP,GYS1,ASS1,GALT,HSPA5,ATIC,ENO2,GALE,GOT1,ATP6V1A,CNDP2,ATP6V1B2,MTHFD1,NARS,PRKAR1A,ATP6V1C1,PGD,PFKM,PGK1,HUWE1,ATOX1,TUBB3,PRKAR1B,GDI1,IMPDH2,PPP1R7,NDRG1,ATP6V1E1,TUBB4B,IPO4,GAPDH,PFKL,IFRD2,FKBP1A,LARS,NEDD4L,GART,NAP1L1,ACSS2,LDHB,BCAT1,AHSA1,AKR1A1,GMPPB,PFKP,HSPA6,PGM1,MAP2K2,UGP2,SHMT1,IARS,CTPS1,PPA1,SRM,MYO1E,ABHD14B,UBA1,TIMP2,AHCY,CUL4B,AACS,IPO5,EEF2,ISYNA1,PDIA3,NAP1L4,PRKAA2,TUBA4A,PYCRL,HSP90B1,HSPH1,PARK7,NUTF2,HSPA4,SDSL,GDI2,GTPBP2,TSR1,NCK1,DSTN,PTGES3,EIF2B2,ISG15,NPEPPS,FYN,PSMD11,MARS,ENO1,ALDOA,PRKCI,CCT5,HSP90AA1,POLR3B,CAD,MYH10,RRM2,EIF2B5,CCT8,PYGB,STIP1,PPME1,ATF2,EIF4A1,PANK4,PPP2R5D,TNIK,DARS,ACTB,ACACA,ACAT2,PPID,YWHAZ,EGFR,HLA-B,PLAA,FHIT,CAND1,PRDX2,EIF4A2,LDHA,ADK,PSMB7,HMGCS1,NUDCD1,HSP90AB1,TSC2,CKB,OLA1,IPO13,ECHDC1,PSMB8,LSM1,CCT7,PKM,VCL,MMS19,YWHAQ,PPP4R1,CKS1B,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,GCLC,CCT4,EIF6,PSMD7,SLC35F6,CLDN12,NSFL1C,CCT3,KPNB1,PSMA2,TALDO1,CTPS2,EIF2S2,PLS3,HSPA1B,PAAF1,MAPK1,CAPZA2,ATG5,DRG2,GPN1,ATP6V1D,THADA,DDX39A,TCP1,MYL1,CSNK1D,TKT,NOM1,HDAC6,FBXO6,SETD1B,PSMB1,FERMT2,PPP6C,COPA,TNPO2,PLS1,CSE1L,IMPDH1,UBA5,TUBA1A,BTF3L4,PSMB2,PSMD6,MYH9,PPAN,FARSA,COPS5,UBE3C,ARF4,TUBB6,VCP,MPI,TUBB,PSMA7,MAT2A,GPI,MOB1B,XPO1,MCM2,KDELR3,PSMC3,EIF5B,ABCF1,BAG6,PPP2R5B,CLUH,IDE,PPP3CB,FTSJ1,PRMT5,PRUNE,AKT1,EIF2S3,PSMB3,TUBB4A,UBE2E2,BUB1,SEC23B,VHL,PRDX5,TRAF4,PSMA1,ASL,PSMA5,ACTR2" -1.697559927 -0.339794572 243 826 MONO-UNSATURATED FATTY ACID BETA-OXIDATION MONO-UNSATURATED FATTY ACID BETA-OXIDATION 0.000125786 0.000264869 -1 "PGRMC2,MAP1LC3A,SQSTM1,GFPT1,APP,XPOT,LAMP1,PDIA4,RRAGA,GALT,HSPA5,ENO2,CALCOCO2,ATP6V1A,ATP6V1B2,PAICS,PFKM,HUWE1,TUBB3,NDUFA4,GDI1,NDRG1,TUBB4B,IPO4,GAPDH,PFKL,IFRD2,LARS,GART,GSTO1,GMPPB,PFKP,HSPA6,PGM1,CTPS1,SPG20,ABHD14B,UBA1,TIMP2,ARMC6,AHCY,EEF2,ISYNA1,PDIA3,PRKAA2,TUBA4A,PYCRL,HSPH1,PARK7,HSPA4,SDSL,GDI2,GTPBP2,PTGES3,EIF2B2,IPO7,ENO1,ALDOA,HSP90AA1,CAD,RRM2,EIF2B5,CCT8,PYGB,STIP1,ATF2,EIF4A1,TNIK,DARS,ACTB,ACACA,PPID,YWHAZ,EGFR,HLA-B,CALR,STAT1,HINT1,EIF4A2,ADK,HSP90AB1,SLC1A5,OLA1,MSN,VCL,MMS19,YWHAQ,NT5C2,HECW2,PSMD7,ABCG1,CLDN12,KPNB1,CTPS2,CLK1,EIF2S2,PLS3,HSPA1B,MAPK1,ATG5,GPN1,ATP6V1D,CSNK1D,TKT,NOM1,FBXO6,FERMT2,PPP6C,TNPO2,PLS1,CSE1L,UBA5,TUBA1A,PFDN4,FARSA,COPS5,TUBB6,VCP,TUBB,GET4,LAMP2,MAT2A,WASL,GPI,MOB1B,SLC27A1,XPO1,MCM2,PSMC3,TUBGCP3,BAG6,CLUH,PPP3CB,RABAC1,FTSJ1" -1.706676567 -0.355819795 135 442 ASCORBATE (VITAMIN C) AND ALDARATE METABOLISM ASCORBATE (VITAMIN C) AND ALDARATE METABOLISM 0.000119689 0.000264869 -1 "SARS,MAP1LC3A,AARS,GFPT1,TBC1D15,APP,GARS,XPOT,CTH,PDIA4,TARS,LGALS3BP,GYS1,ASS1,GALT,HSPA5,ATIC,ENO2,GALE,GOT1,ATP6V1A,CNDP2,ATP6V1B2,MTHFD1,NARS,PRKAR1A,ATP6V1C1,PGD,PFKM,PGK1,HUWE1,TUBB3,PRKAR1B,GDI1,IMPDH2,PPP1R7,ATP6V1E1,TUBB4B,IPO4,GAPDH,PFKL,FKBP1A,LARS,NEDD4L,GART,NAP1L1,ACSS2,BCAT1,GSTO1,AKR1A1,GMPPB,PFKP,HSPA6,PGM1,MAP2K2,UGP2,SHMT1,IARS,CTPS1,PPA1,SRM,MYO1E,UBA1,AHCY,MAPRE1,IPO5,EEF2,ISYNA1,PDIA3,NAP1L4,PRKAA2,TUBA4A,PYCRL,HSPH1,NUTF2,HSPA4,SDSL,GDI2,TSR1,DSTN,PTGES3,EIF2B2,NPEPPS,PSMD11,MARS,ENO1,ALDOA,PRKCI,CCT5,HSP90AA1,POLR3B,CAD,MYH10,RRM2,EIF2B5,CCT8,PYGB,STIP1,EIF4A1,DARS,ACTB,ACACA,ACAT2,PPID,YWHAZ,EGFR,WDR1,PLAA,FHIT,CALR,CAND1,PRDX2,HINT1,EIF4A2,ADK,HMGCS1,TXN,HSP90AB1,TSC2,OLA1,IPO13,LSM1,CCT7,MSN,AKR1B1,MMS19,CKS1B,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,GCLC,ARHGDIA,CCT4,EIF6,PSMD7,SLC35F6,NSFL1C,CCT3,KPNB1,TALDO1,CTPS2,EIF2S2,PLS3,HSPA1B,PAAF1,MAPK1,CAPZA2,DRG2,GPN1,ATP6V1D,THADA,TCP1,MYL1,CSNK1D,TKT,NOM1,FBXO6,SETD1B,PPP6C,COPA,TNPO2,PLS1,CSE1L,IMPDH1,UBA5,TUBA1A,BTF3L4,PSMD6,MYH9,PPAN,FARSA,UBE3C,ARF4,TUBB6,VCP,MPI,TUBB,PSMA7,MAT2A,EIF3B,GPI,MOB1B,XPO1,MCM2,PSMC3,EIF5B,PDCL3,TCEA1,CLUH,IDE,PPP3CB,PRMT5,PRUNE,EIF2S3,TUBB4A,BUB1,SEC23B,PRDX5" -1.896025472 -0.385881523 200 617 POLYUNSATURATED FATTY ACID BIOSYNTHESIS POLYUNSATURATED FATTY ACID BIOSYNTHESIS 0.000121124 0.000264869 -1 "SARS,MAP1LC3A,SQSTM1,AARS,GFPT1,APP,GARS,CTH,LAMP1,PDIA4,TARS,GALT,HSPA5,ATIC,ACY1,ENO2,GOT1,ATP6V1A,ATP6V1B2,MTHFD1,NARS,PRKAR1A,ATP6V1C1,PGD,PFKM,HUWE1,UBE2V1,TUBB3,PRKAR1B,GDI1,ATP6V1E1,TUBB4B,PSMD9,IPO4,GAPDH,PFKL,FKBP1A,LARS,NEDD4L,GART,ACSS2,BCAT1,GSTO1,SRRM2,AKR1A1,GMPPB,CDK6,PFKP,HSPA6,PGM1,UGP2,ADSL,SHMT1,IARS,FASN,CTPS1,PPA1,UBA1,ARMC6,AHCY,EEF2,ISYNA1,EPRS,PDIA3,PRKAA2,VTA1,TUBA4A,HSPH1,NUTF2,HSPA4,GDI2,TSR1,DSTN,MRPS17,CLN3,NPEPPS,PSMD11,MARS,DYRK1A,ENO1,ALDOA,CCT5,HSP90AA1,POLR3B,CAD,RRM2,CCT8,DNM1L,PYGB,STIP1,ATF2,EIF4A1,DARS,ACTB,ACACA,ACAT2,PPID,YWHAZ,EGFR,CALR,PRDX2,CDK5,HINT1,EIF4A2,ADK,HMGCS1,HSP90AB1,OLA1,CCT7,MSN,VCL,MMS19,YWHAQ,PPIA,AKR1D1,KRI1,HECW2,CCT4,YWHAG,EIF6,ABCG1,CCT3,DDX3X,KPNB1,TALDO1,CTPS2,PLS3,HSPA1B,MAPK1,ATG5,MYL1,CSNK1D,TKT,FBXO6,PPP6C,TNPO2,PLS1,CSE1L,UBA5,TUBA1A,BTF3L4,CDC37,PFDN4,MYH9,FARSA,ARF4,TUBB6,VCP,MPI,TUBB,RAB6C,LAMP2,MAT2A" -1.719090097 -0.352271026 153 550 ALANINE AND ASPARTATE METABOLISM ALANINE AND ASPARTATE METABOLISM 0.000120613 0.000264869 -1 "SARS,MAP1LC3A,AARS,GFPT1,APP,GARS,LAMP1,PDIA4,TARS,GYS1,ASS1,GALT,HSPA5,ATIC,ENO2,GOT1,ATP6V1A,ATP6V1B2,PRKAG2,ASNS,IDH1,NARS,PRKAR1A,ATP6V1C1,PGD,PFKM,PGK1,HUWE1,TPI1,TUBB3,PRKAR1B,GDI1,IMPDH2,PPP1R7,ATP6V1E1,TUBB4B,IPO4,GAPDH,PFKL,FKBP1A,LARS,NEDD4L,GART,NAP1L1,ACSS2,APRT,FLNC,GMPPB,PFKP,HSPA6,MAP2K2,BAG3,UGP2,PEBP1,SHMT1,IARS,GMPR2,CTPS1,PPA1,XPNPEP1,UBA1,AHCY,EEF2,TAGLN2,ISYNA1,PDIA3,NAP1L4,TUBA4A,PYCRL,HSPH1,NUTF2,HSPA4,SDSL,GDI2,NCK1,DSTN,NAA50,NPEPPS,FYN,PSMD11,ALDOA,HSP90AA1,POLR3B,CAD,FBP1,RRM2,CCT8,ABCE1,PYGB,STIP1,ATF2,ARAF,EIF4A1,TNIK,ACTB,ACACA,ACAT2,PPID,YWHAZ,EGFR,HLA-B,PRDX2,HINT1,EIF4A2,HMGCS1,HSP90AB1,OLA1,FNTA,SORT1,LSM1,CCT7,PKM,AKR1B1,PPIA,PPP2CB,KRI1,COPB1,TP53RK,CCT4,YWHAG,PSMD7,NSFL1C,CCT3,DYNC1LI2,CTPS2,CLK1,EIF2S2,HSPA1B,MAPK1,ATG5,GPN1,TCP1,CSNK1D,TKT,HDAC6,FBXO6,PPP6C,COPA,GMPR,USP4,CSE1L,IMPDH1,DNAJC21,TUBA1A,BTF3L4,BCAR3,PSMB2,PSMD6,PFDN4,PPAN,LATS1,FARSA,COPS5,ATE1,TUBB6,VCP,MPI,TUBB,DCUN1D1,LAMP2,MAT2A,GPI,MOB1B,XPO1,ETF1,GIT1,PSMC3,ABCF1,SAR1A,NIT2,FBXO21,CLUH,IDE,FTSJ1,EIF2S3,PSMB3,TUBB4A,SEC23B,PRDX5,ASL,DDX52,ACTR2" -1.923868934 -0.393373568 182 573 GLUTATHIONE METABOLISM GLUTATHIONE METABOLISM 0.000126598 0.000264869 -1 "SARS,GFPT1,LAMP1,PDIA4,TARS,GALT,HSPA5,ATIC,ABL2,ENO2,GALE,GOT1,ATP6V1A,ATP6V1B2,ATP6V1C1,TSG101,PGD,PFKM,GSS,TUBB3,NDUFA4,IMPDH2,ATP6V1E1,TUBB4B,IPO4,GAPDH,CTSL,PFKL,NAMPT,FKBP1A,GART,NAP1L1,ACSS2,IPO9,GMPPB,PFKP,HSPA6,TMEM248,PGM1,UGP2,CTPS1,PPA1,SRM,DPH1,UBA1,AHCY,IPO5,EEF2,EPRS,PDIA3,NAP1L4,TUBA4A,PYCRL,HSP90B1,HSPH1,NUTF2,HSPA4,SGTA,DSTN,FYN,IPO7,HSP90AA1,DCTN1,CAD,RRM2,OPLAH,CCT8,ABCE1,DNM1L,STIP1,ATF2,EIF4A1,TNIK,ACTB,ACACA,PPID,HLA-B,PRDX2,EIF4A2,ADK,COPS7A,HMGCS1,TXN,HSP90AB1,CEP170,OLA1,LSM1,CCT7,PKM,SFN,PPIA,COPB1,GCLC,CCT4,EIF6,ABCG1,CCT3,CTPS2,EIF2S2,IRF3,HSPA1B,ATG5,GPN1,ASNA1,GPX1,UBQLN1,TCP1,CSNK1D,NOM1,KPNA3,FBXO6,PPP6C,COPA,CSE1L,IMPDH1,TUBA1A,BTF3L4,PSMB2,PSMD6,PFDN4,UMPS,ISCU,FARSA,COPS5,TUBB6,VCP,TUBB,LAMP2,MAT2A,EIF3B,ATAD3A,CAP2,GPI,XPO1,MCM2,PSMC3,CAP1,CLUH,INPPL1,FTSJ1" -1.851283642 -0.386977692 140 431 TCA CYCLE TCA CYCLE 0.000112108 0.000264869 -1 "SARS,MAP1LC3A,SQSTM1,AARS,HSPB1,GFPT1,APP,GARS,CTH,PDIA4,TARS,LGALS3BP,GYS1,ASS1,GALT,HSPA5,ATIC,ENO2,GALE,WARS,GOT1,ATP6V1A,CNDP2,ATP6V1B2,MTHFD1,ASNS,IDH1,NARS,PRKAR1A,ATP6V1C1,TSG101,PGD,PFKM,PGK1,HUWE1,TPI1,TUBB3,NDUFA4,PRKAR1B,GDI1,IMPDH2,PPP1R7,NDRG1,ATP6V1E1,TUBB4B,PSMD9,IPO4,GAPDH,PFDN2,CTSL,PFKL,FKBP1A,VPS4B,LARS,ACLY,NEDD4L,MDH1,GART,NAP1L1,ACSS2,LDHB,BCAT1,IPO9,APRT,AHSA1,GSTO1,SRRM2,CCS,AKR1A1,GMPPB,CDK6,PFKP,HSPA6,PGM1,MAP2K2,UGP2,PEBP1,ADSL,HARS,SHMT1,IARS,GMPR2,FASN,CTPS1,PPA1,XPNPEP1,UBA1,AHCY,ACO1,MAPRE1,IPO5,EEF2,TAGLN2,ISYNA1,EPRS,PDIA3,NAP1L4,PRKAA2,TUBA4A,PYCRL,HSP90B1,HSPH1,PARK7,NUTF2,HSPA4,SDSL,GDI2,NAA15,TSR1,DSTN,SPRY2,PTGES3,SH3GL1,ISG15,NPEPPS,PSMD11,MARS,IPO7,DYRK1A,ENO1,UBE2M,ALDOA,CCT5,HSP90AA1,POLR3B,CAD,ARRB2,WWP2,RRM2,CCT8,ABCE1,DNM1L,NUP62,PYGB,STIP1,PPME1,ATF2,ARPC4,EIF4A1,PPP2R5D,HGS,DARS,ACTB,ACACA,ACAT2,AK1,PPID,YWHAZ,EGFR,HLA-B,FHIT,CALR,CAND1,PRDX2,NOTCH2,CDK5,HINT1,EIF4A2,LDHA,ADK,PSMB7,HMGCS1,ARPC3,TXN,HSP90AB1,UBR4,CDA,OLA1,DDI2,TSC22D3,CCT7,PKM,MSN,VCL,AKR1B1,MMS19,YWHAQ,ABCF3,GNPNAT1,VBP1,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,ARHGDIA,TP53RK,CCT4,YWHAG,EIF6,PSMD7,ABCG1,SHC1,NSFL1C,CCT3,DDX3X,KPNB1,PSMA2,TALDO1,CTPS2,EIF2S2,PLS3,TNFRSF10D,HSPA1B,PAAF1,MAPK1,CAPZA2,ATG5,DRG2,GPN1,ATP6V1D,UBQLN1,DDX39A,TCP1,MYL1,FLII,CSNK1D,NOTCH3,TKT,NOM1,HDAC6,ILK,SH3KBP1,FBXO6,ARFGEF2,PSMB1,PPP6C,COPA,GMPR,TNPO2,PLS1,CSE1L,IMPDH1,DNAJC21,TUBA1A,BTF3L4,SH3RF1,BCAR3,PSMB2,PSMD6,PFDN4,PPAN,IKBKG,UMPS,FARSA,COPS5,ATE1,ARF4,TUBB6,VCP,ARRB1,MPI,FOXO1,TUBB,RAB6C,VPS4A,SIRT2,DCUN1D1,MAT2A,ATAD3A,CAP2,ARPC5,GPI,MOB1B,XPO1,ETF1,MCM2,PSMC3,ABCF1,SAR1A,RABIF,FBXO21,CAP1,BAG6,PPP2R5B,CLUH,IDE,PRMT5,PRUNE,AKT1,ARPC2,EIF2S3,PSMB3,TUBB4A,CAPZB,PXN,SEC23B,VHL,PRDX5,ASL,DDX52,PSMA5,KCMF1,ACTR2" -1.737584397 -0.344578156 294 1000 3-CHLOROACRYLIC ACID DEGRADATION 3-CHLOROACRYLIC ACID DEGRADATION 0.000120005 0.000264869 -1 "SARS,MAP1LC3A,AARS,GFPT1,TBC1D15,APP,GARS,XPOT,CTH,PDIA4,TARS,LGALS3BP,GYS1,ASS1,GALT,HSPA5,ATIC,TNIP1,ENO2,GALE,GOT1,ATP6V1A,CNDP2,ATP6V1B2,MTHFD1,NARS,PRKAR1A,ATP6V1C1,PGD,PFKM,HUWE1,TUBB3,PRKAR1B,GDI1,IMPDH2,PPP1R7,ATP6V1E1,TUBB4B,IPO4,GAPDH,PRDX1,PFKL,FKBP1A,LARS,NEDD4L,GART,NAP1L1,ACSS2,BCAT1,AKR1A1,GMPPB,PFKP,HSPA6,PGM1,MAP2K2,UGP2,SHMT1,IARS,CTPS1,PPA1,SRM,MYO1E,UBA1,AHCY,IPO5,EEF2,ISYNA1,PDIA3,NAP1L4,PRKAA2,TUBA4A,PYCRL,HSPH1,NUTF2,HSPA4,SDSL,GDI2,TSR1,DSTN,EIF2B2,NPEPPS,PSMD11,MARS,ENO1,PRKCI,CCT5,HSP90AA1,POLR3B,CAD,MYH10,RRM2,EIF2B5,CCT8,PYGB,STIP1,EIF4A1,DARS,ACTB,ACACA,ACAT2,PPID,EGFR,PLAA,FHIT,CAND1,PRDX2,EIF4A2,ADK,HMGCS1,HSP90AB1,TSC2,OLA1,IPO13,LSM1,CCT7,MMS19,CKS1B,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,GCLC,CCT4,EIF6,PSMD7,SLC35F6,NSFL1C,CCT3,KPNB1,TALDO1,CTPS2,EIF2S2,PLS3,HSPA1B,PAAF1,MAPK1,CAPZA2,DRG2,GPN1,ATP6V1D,THADA,TCP1,MYL1,CSNK1D,TKT,NOM1,FBXO6,SETD1B,PPP6C,COPA,TNPO2,PLS1,CSE1L,IMPDH1,UBA5,TUBA1A,BTF3L4,PSMD6,MYH9,PPAN,FARSA,UBE3C,ARF4,TUBB6,VCP,ARRB1,MPI" -1.832454152 -0.373602649 168 600 ARACHIDONIC ACID METABOLISM ARACHIDONIC ACID METABOLISM 0.000113469 0.000264869 -1 "PGRMC2,SDCBP,SARS,MAP1LC3A,SQSTM1,HSPB1,GFPT1,APP,F10,LAMP1,PDIA4,SNX2,PDCD6IP,CRELD2,GALT,HSPA5,ATIC,ABL2,ACY1,ENO2,SLC3A2,GALE,WARS,ATP6V1A,ATP6V1B2,RPS6KA3,NARS,PFKM,HUWE1,UBE2V1,TUBB3,NDUFA4,GDI1,EIF2A,TUBB4B,PSMD9,IPO4,GAPDH,GSTM3,CTSL,PFKL,NAMPT,IKBKB,IFRD2,PRDX6,FKBP1A,VPS4B,NEDD4L,TGM2,BLMH,PDXDC1,LDHB,COTL1,IPO9,APRT,AHSA1,GSTO1,GMPPB,RAB3GAP1,CDK6,PFKP,HSPA6,BAG3,NAE1,GSTM1,PEBP1,IARS,FASN,ARFGAP1,ABHD14B,PSME1,UBA1,TIMP2,ARMC6,AHCY,MAPRE1,EEF2,ISYNA1,EPRS,PDIA3,FKBP4,PRKAA2,VTA1,TUBA4A,CBR3,HSP90B1,HSPH1,PARK7,HSPA4,GDI2,GTPBP2,SGTA,NAA15,NAA50,GSTCD,DBNL,MRPS17,PTPN11,PTGES3,EIF2B2,ISG15,NPEPPS,DYRK1A,ENO1,UBE2M,ALDOA,HSP90AA1,DCTN1,CAD,HNRNPM,ARRB2,WWP2,DERA,CCT8,ABCE1,PIK3R1,PYGB,STIP1,EPS8L2,ATF2,UBE2R2,GSTP1,TNIK,PCBP1,ACTB,AK1,PPID,YWHAZ,EGFR,HLA-B,CALR,CBR1,STAT1,CDK5,HINT1,SH3GLB1,LDHA,USP5,MLLT4,ARL1,COPS7A,ARPC3,HSP90AB1,SLC1A5,UBE2O,LTA4H,ARMT1,XPO7,TPP2,SPINT2,CCT7,SNX3,PKM,MSN,VCL,AKR1B1,YWHAQ,CASP7,PPIA,PPP2CB,ZFP36,COPB1,DVL2,HECW2,CCT4,YWHAG,ALDH16A1,AIP,CLDN12,CCT3,CASP3,DDX3X,KPNB1,CLK1,EIF2S2,STUB1,HSPA1B,MAPK1,ATG5,CARHSP1,PSMF1,ASNA1,CAB39,GPX1,UBQLN1,DDX39A,RAB3GAP2,GNB1L,TKT,KPNA3,HDAC6,DNAJC7,FBXO6,FERMT2,TNPO2,PLS1,USP4,CSE1L,UBA5,PIP4K2A,TUBA1A,OGFR,UBXN1,LDLR,CDC37,DTD1,XAGE1A,PSMB2,PFDN4,UMPS,FARSA,COPS5,CHCHD2,CDC34,RAD23B,TUBB6,VCP,ARRB1,CD2AP,AIMP1,TUBB,LSM3,VPS4A,DCUN1D1,LAMP2,MAT2A,CARM1,ATAD3A,TRAF2" -1.441577982 -0.286702943 229 950 LIMONENE AND PINENE DEGRADATION LIMONENE AND PINENE DEGRADATION 0.000119076 0.000264869 -1 "SARS,MAP1LC3A,AARS,GFPT1,TBC1D15,APP,GARS,XPOT,CTH,PDIA4,TARS,LGALS3BP,GYS1,ASS1,GALT,HSPA5,ATIC,ENO2,GALE,GOT1,ATP6V1A,CNDP2,ATP6V1B2,MTHFD1,NARS,PRKAR1A,ATP6V1C1,PGD,PFKM,HUWE1,TUBB3,PRKAR1B,GDI1,IMPDH2,PPP1R7,ATP6V1E1,TUBB4B,IPO4,GAPDH,PFKL,IFRD2,FKBP1A,LARS,NEDD4L,GART,NAP1L1,ACSS2,BCAT1,AKR1A1,GMPPB,PFKP,HSPA6,PGM1,MAP2K2,UGP2,SHMT1,IARS,CTPS1,PPA1,SRM,MYO1E,ABHD14B,UBA1,TIMP2,AHCY,IPO5,EEF2,ISYNA1,PDIA3,NAP1L4,PRKAA2,TUBA4A,PYCRL,HSPH1,PARK7,NUTF2,HSPA4,SDSL,GDI2,GTPBP2,TSR1,DSTN,PTGES3,EIF2B2,NPEPPS,PSMD11,MARS,ENO1,PRKCI,CCT5,HSP90AA1,POLR3B,CAD,MYH10,RRM2,EIF2B5,CCT8,PYGB,STIP1,EIF4A1,TNIK,DARS,ACTB,ACACA,ACAT2,PPID,YWHAZ,EGFR,HLA-B,PLAA,FHIT,CAND1,PRDX2,EIF4A2,ADK,HMGCS1,HSP90AB1,TSC2,OLA1,IPO13,LSM1,CCT7,MMS19,CKS1B,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,GCLC,CCT4,EIF6,PSMD7,SLC35F6,CLDN12,NSFL1C,CCT3,KPNB1,TALDO1,CTPS2,EIF2S2,PLS3,HSPA1B,PAAF1,MAPK1,CAPZA2,ATG5,DRG2,GPN1,ATP6V1D,THADA,TCP1,MYL1,CSNK1D,TKT,NOM1,FBXO6,SETD1B,FERMT2,PPP6C,COPA,TNPO2,PLS1,CSE1L,IMPDH1,UBA5,TUBA1A,BTF3L4,PSMD6,MYH9,PPAN,FARSA,UBE3C,ARF4,TUBB6,VCP,MPI,TUBB,MAT2A,GPI,MOB1B,XPO1,MCM2,PSMC3,EIF5B,BAG6,CLUH,IDE,PPP3CB,FTSJ1,PRMT5,PRUNE,EIF2S3,TUBB4A,BUB1,SEC23B,VHL,PRDX5" -1.833012574 -0.372325359 198 636 ARGININE AND PROLINE METABOLISM ARGININE AND PROLINE METABOLISM 0.000113856 0.000264869 -1 "SDCBP,SARS,MAP1LC3A,AARS,HSPB1,GFPT1,TBC1D15,APP,GARS,XPOT,CTH,LAMP1,PDIA4,TARS,LGALS3BP,GYS1,ASS1,GALT,HSPA5,ATIC,ENO2,SLC3A2,GALE,GOT1,RNF31,ATP6V1A,CNDP2,ATP6V1B2,MTHFD1,COPRS,NARS,PRKAR1A,ATP6V1C1,PGD,PFKM,HUWE1,ATOX1,TUBB3,PRKAR1B,GDI1,IMPDH2,PPP1R7,NDRG1,ATP6V1E1,TUBB4B,IPO4,GAPDH,PFKL,FKBP1A,LARS,NUDT5,NEDD4L,GART,NAP1L1,ACSS2,BCAT1,AKR1A1,GMPPB,PFKP,HSPA6,PGM1,MAP2K2,AHNAK2,BAG3,UGP2,SHMT1,IARS,FASN,CTPS1,PSEN2,PPA1,SRM,MYO1E,UBA1,ARMC6,AHCY,IPO5,EEF2,ISYNA1,GSPT1,PDIA3,NAP1L4,PLEC,PRKAA2,TUBA4A,PYCRL,HSPH1,PARK7,NUTF2,HSPA4,SDSL,GDI2,NIF3L1,TSR1,DSTN,NAA50,PTGES3,EIF2B2,NPEPPS,GCDH,PSMD11,MARS,IPO7,ENO1,ALDOA,PRKCI,CCT5,HSP90AA1,POLR3B,CAD,ARRB2,FBP1,MYH10,RRM2,DNM2,EIF2B5,CCT8,PYGB,STIP1,ATF2,ARAF,EIF4A1,CSNK1G3,HGS,TNIK,PCBP1,DARS,ACTB,ACACA,ACAT2,ALDH3B1,PPID,YWHAZ,EGFR,PI4K2A,HLA-B,PLAA,FHIT,CAND1,PRDX2,EIF4A2,ADK,PSMB7,HMGCS1,TXN,HSP90AB1,TSC2,CEP170,BABAM1,OLA1,VAC14,IPO13,FNTA,SORT1,VASP,LSM1,CCT7,AKR1B1,MMS19,YWHAQ,CASP7,CKS1B,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,GCLC,NFKB1,ATP2B4,FAT1,CCT4,YWHAG,EIF6,PSMD7,SLC35F6,SHC1,NSFL1C,CCT3,DYNC1LI2,DDX3X,KPNB1,PSMA2,TALDO1,CTPS2,SAT2,CLK1,EIF2S2,STUB1,PLS3,HSPA1B,PAAF1,MAPK1,CAPZA2,PARP4,ATG5,DRG2,GPN1,ATP6V1D,THADA,DDX39A,TCP1,MYL1,CSNK1D,RC3H1,TKT,NOM1,DNAJC7,FBXO6,SETD1B,PPP6C,SLC7A5,COPA,TNPO2,PLS1,USP4,CSE1L,IMPDH1,UBA5,DNAJC21,FUNDC2,TUBA1A,BTF3L4,BCAR3,CDC37,PSMD6,MYH9,PPAN,UMPS,LATS1,ZSWIM8,FARSA,GSPT2,UBE3C,ARF4,TUBB6,P4HA1,VCP,ARRB1,MPI,TUBB,PSMA7,LAMP2,MAT2A,NEK7,WASL,KRT18,RMND5A,GPI,MOB1B,XPO1,MCM2,GIT1,PSMC3,EIF5B,DNM1,TCEA1,CLUH,RELA,IDE,PPP3CB,EXOC6,FTSJ1,PRMT5,PRUNE,AKT1,EIF2S3,TUBB4A,BUB1,PXN,SEC23B,VHL,PRDX5,PSMA1,ASL,TCEB2,PSMA5,ACTR2" -1.684031203 -0.33536933 278 918 GLYCEROPHOSPHOLIPID METABOLISM GLYCEROPHOSPHOLIPID METABOLISM 0.000108073 0.000264869 -1 "RPTOR,PGRMC2,SDCBP,SARS,MAP1LC3A,SQSTM1,AARS,HSPB1,GFPT1,CLU,TBC1D15,APP,GNPDA1,GARS,XPOT,CTH,PDIA4,METAP2,TARS,LGALS3BP,SPIRE1,GYS1,ASS1,CRELD2,GALT,HSPA5,ATIC,TNIP1,SLC4A2,ACY1,ENO2,GALE,GOT1,RNF31,CALCOCO2,ATP6V1A,CNDP2,ATP6V1B2,MTHFD1,RPS6KA3,ASNS,IDH1,NARS,PRKAR1A,ATP6V1C1,TSG101,ABHD5,PAICS,PGD,PFKM,PGK1,HUWE1,PDIA6,TUBB3,NDUFA4,PRKAR1B,GDI1,PCYT2,IMPDH2,PPP1R7,ATP6V1E1,TUBB4B,IPO4,GAPDH,PRDX1,PFKL,FAH,PRDX6,FKBP1A,LARS,NEDD4L,GART,NAP1L1,ACSS2,LDHB,BCAT1,SERINC5,SEC31A,APRT,AHSA1,GSTO1,AKR1A1,GMPPB,CDK6,PFKP,HSPA6,PGM1,MAP2K2,APOC3,BAG3,UGP2,EIF4EBP1,SHMT1,IARS,PRPS2,CTPS1,ARFGAP1,PSEN2,ALDOC,PPA1,SRM,MYO1E,UBA1,PKN3,PAFAH1B3,AHCY,CUL4B,IPO5,EEF2,ISYNA1,EPRS,PDIA3,PAFAH1B1,NAP1L4,LAMB1,TSPAN3,PRKAA2,TUBA4A,PYCRL,HSP90B1,HSPH1,NUTF2,HSPA4,SDSL,GDI2,BAX,SGTA,TSR1,GK3P,DSTN,SCAMP3,CLN3,GSK3A,PTGES3,LRRC16A,EIF2B2,ISG15,NPEPPS,PSMD11,UBE2Z,MARS,DYRK1A,ENO1,ALDOA,PRKCI,CCT5,HSP90AA1,POLR3B,CAD,ARRB2,ECM29,MYH10,RRM2,OPLAH,EIF2B5,CCT8,ABCE1,BIN1,PYGB,STIP1,EEF2K,ZFP36L1,CHTF18,ATF2,UBQLN2,EIF4A1,UBE2R2,HGS,CHMP7,ESD,DARS,ASPSCR1,ACTB,ACACA,ACAT2,PPID,YWHAZ,EGFR,WDR1,HLA-B,PLAA,FHIT,LPIN3,SERINC1,CRK,CALR,CAND1,PRDX2,NOTCH2,HINT1,SLC38A1,ATG16L1,EIF4A2,LDHA,USP5,ADK,HMGCS1,TXN,HSP90AB1,UBE2O,TSC2,CEP170,PLEKHM1,CKB,KLC2,OLA1,IPO13,SORT1,DYSF,RNASEH2A,LSM1,CCT7,PKM,MSN,AKR1B1,MMS19,YWHAQ,CASP7,CNPY2,CKS1B,ABCF3,GNPNAT1,VBP1,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,GCLC,DVL2,SLC23A2,WIPI2,AKR7A2,NFKB1,NTPCR,ARHGDIA,HECW2,NME7,CCT4,YWHAG,EIF6,PSMD7,SLC35F6,FRYL,NSFL1C,CCT3,PEA15,CASP3,NUDC,KPNB1,BMPR1A,OSBPL11,TALDO1,IST1,CTPS2,BRAF,LRSAM1,EIF2S2,METAP1,PLS3,ITGB4,AKR1C3,HSPA1B,PAAF1,MAPK1,CAPZA2,PTS,DRG2,CARHSP1,GPN1,GLO1,SERINC3,ATP6V1D,UBQLN1,THADA,APOB,TCP1,MYL1,CSNK1D,RC3H1,NOTCH3,PAFAH1B2,TKT,NOM1,ILK,FBXO6,ARFGEF2,SETD1B,PPP6C,COPA,UGGT1,PSMG2,TNPO2,PLS1,USP4,CSE1L,IMPDH1,UBA5,ARHGAP1,SCAMP2,NDUFB8,TEX264,TUBA1A,BTF3L4,PLCG1,UBXN1,XAGE1A,PNPLA2,PSMB2,PSMD6,SNX9,ITGB3,DAGLB,MYH9,PPAN,UMPS,LATS1,FARSA,COPS5,UBE3C,MAP2K3,AGAP3,RAD23B,ARF4,TUBB6,VCP,ARRB1,MPI,AIMP1,TUBB,RAB6C,LPIN1,PSMA7,SIRT2,MAT2A,TRAF2,CAP2,WASL,KRT18,COPS4,GPI,MOB1B,SLC27A1,PTPRK,XPO1,MEPCE,PKN1,PMF1,MCM2,KDELR3,PSMC3,EIF5B,ABCF1,EIF4G1,MPZL1,AP3B1,CAP1,BAG6,POMP,SOAT1,NDUFB1,CLUH,RELA,IDE,PPP3CB,RHEB,MAP3K7,INPPL1,FTSJ1,PRMT5,PRUNE,AKT1,AP3D1,CASP8,EIF2S3,PSMB3" -1.652221014 -0.323869388 376 1364 GLUTAMATE METABOLISM GLUTAMATE METABOLISM 0.000131944 0.000264869 -1 "SARS,AARS,GFPT1,APP,GARS,TARS,LGALS3BP,HSPA5,ATIC,ENO2,ATP6V1B2,NARS,ATP6V1C1,PGD,PFKM,IMPDH2,ATP6V1E1,GAPDH,PFDN2,PFKL,FKBP1A,LARS,NEDD4L,ACSS2,GMPPB,PFKP,HSPA6,UGP2,SHMT1,IARS,CTPS1,PPA1,UBA1,ARMC6,AHCY,EEF2,ISYNA1,TUBA4A,HSPH1,NUTF2,HSPA4,NCK1,DSTN,ISG15,NPEPPS,FYN,ENO1,ALDOA,HSP90AA1,CAD,MYH10,RRM2,ATF2,ARAF,EIF4A1,TNIK,DARS,ASPSCR1,ACTB,ACAT2,YWHAZ,HLA-B,PRDX2,EIF4A2,HMGCS1,HSP90AB1,BABAM1,OLA1,MT-ND5,PKM,YWHAQ,PPIA,GCLC,NFKB1,NME7,YWHAG,CTPS2,HSPA1B,MAPK1,ATG5,ATP6V1D,ASB1,CSNK1D,DNAJC7,FBXO6,CSE1L,IMPDH1,UBA5,DNAJC21,TUBA1A,BTF3L4,BCAR3,PFDN4,MYH9,FARSA,VCP,MAT2A,GPI,XPO1,MCM2,PSMC3,ABCF1,MRM1,CLUH,FTSJ1" -1.959202209 -0.420091394 105 313 PHOSPHATIDYLINOSITOL PHOSPHATE METABOLISM PHOSPHATIDYLINOSITOL PHOSPHATE METABOLISM 0.000105764 0.000264869 -1 "RPTOR,NDFIP2,SDCBP,SARS,MAP1LC3A,SQSTM1,AARS,HSPB1,GFPT1,TBC1D15,APP,GARS,XPOT,CTH,LAMP1,PDIA4,TARS,GYS1,PDCD6IP,ASS1,GALT,HSPA5,ATIC,ABL2,TNIP1,ENO2,LAMC1,TOM1,GOT1,ATP6V1A,CNDP2,ATP6V1B2,MTHFD1,RPS6KA3,PRKAG2,NARS,PRKAR1A,ATP6V1C1,TSG101,NDFIP1,PAICS,PGD,PFKM,PGK1,HUWE1,TPI1,PDIA6,TUBB3,NDUFA4,PRKAR1B,GDI1,IMPDH2,PPP1R7,ATP6V1E1,TUBB4B,PSMD9,IPO4,CTTN,IRS2,GAPDH,PGLS,PRDX1,CTSL,ASAP1,ARHGEF2,PFKL,PRDX6,NUBP2,FKBP1A,VPS4B,LARS,PREP,CRKL,MET,NEDD4L,TGM2,GART,NAP1L1,ACSS2,PDXDC1,LDHB,BCAT1,SERINC5,HGH1,MTMR14,FLNC,BAD,AHSA1,GSTO1,AKR1A1,IMPA1,GMPPB,PFKP,HSPA6,PGM1,MAP2K2,BAG3,UGP2,TP53BP2,EIF4EBP1,ADSL,SHMT1,IARS,PRPS2,KEAP1,FASN,CTPS1,ARFGAP1,ALDOC,TNFRSF10B,AAMP,PPA1,SRM,MYO1E,UBA1,DCTN2,VPS35,TGFBR2,PKN3,AHCY,CUL4B,MAPRE1,IPO5,NADSYN1,EEF2,IPO11,ISYNA1,FGFR1,EPRS,PDIA3,FKBP4,NAP1L4,PLEC,TSPAN3,PRKAA2,SLC2A3,MTRR,TUBA4A,PPP2R4,PYCRL,HSP90B1,HSPH1,PARK7,TRIP10,NUTF2,HSPA4,SDSL,GDI2,EZR,KIF5B,SYNJ2,TSR1,NCK1,DSTN,TOLLIP,SPRY2,PTPN11,GSK3A,PTGES3,EIF2B2,SH3GL1,DYNC1H1,ISG15,NPEPPS,FYN,PSMD11,IPO7,MAP2K1,ENO1,PRKAA1,CLIC1,ALDOA,LAMA5,CCT5,HSP90AA1,POLR3B,DCTN1,CAD,ARRB2,MYH10,WWP2,RRM2,DNM2,EIF2B5,CCT8,ABCE1,AKAP2,CLIC4,DNM1L,NUP62,PIK3R1,PIP4K2C,USP9X,DIAPH1,BIN1,PYGB,STIP1,PPME1,EPS8L2,PACSIN1,ATF2,ARPC4,MRPL45,EIF4A1,HGS,ESD,PCBP1,DARS,CAST,ACTB,ACACA,ACAT2,PPID,YWHAZ,EGFR,WDR1,PI4K2A,HLA-B,SERINC1,CRK,CALR,PRDX2,NOTCH2,STAT1,CDK5,TSNAX,HINT1,SH3GLB1,EIF4A2,ADK,HMGCS1,ARPC3,TXN,HSP90AB1,PFDN1,PITPNA,CEP170,SSFA2,CA13,KLC2,EIF4B,OLA1,VAC14,CC2D1B,DDI2,FNBP4,SORT1,VASP,RNASEH2A,PRKCZ,SPINT2,LSM1,CCT7,SNX3,MTM1,PKM,SNX12,FN3K,MSN,SFN,AKR1B1,MMS19,YWHAQ,PTK2,VBP1,REPS2,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,DVL2,ABCC3,WIPI2,DCTN3,NFKB1,ATG7,SORBS2,ARHGDIA,HECW2,AAK1,CCT4,YWHAG,EIF6,PSMD7,PDAP1,FRYL,PA2G4,SHC1,NSFL1C,CCT3,DYNC1LI2,PEA15,DDX3X,KPNB1,OSBPL11,TALDO1,CTPS2,CLK1,EIF2S2,HPS6,STUB1,PLS3,ITGB4,AP3M2,IRF3,HSPA1B,CPTP,GAPVD1,MAPK1,OTUD6B,CAPZA2,ATG5,GPN1,ASNA1,SERINC3,SH3BP2,ATP6V1D,PIGA,UBQLN1,KIF1B,APOB,TCP1,MYL1,EXOC8,CSNK1D,RC3H1,MST1R,PFKFB2,NOTCH3,TKT,NOM1,ILK,APEX1,PNPO,MYL12A,SH3KBP1,INPP4A,FBXO6,ABI1,ARFGEF2,CHMP3,PPP6C,COPA,EPS15,UGGT1,TNPO2,PLS1,USP4,CSE1L,IMPDH1,DNAJC21,SEPT9,PIP4K2A,TEX264,TUBA1A,BTF3L4,SCYL1,PLCG1,STX3,LDLR,CDC37,HERPUD1,SNX9,ITGB3,MYH9,UMPS,LATS1,FNBP1,DCTN5,FARSA,TTC1,UBE3C,MAP2K3,AGAP3,RAD23B,ARF4,TUBB6,VCP,ARRB1,MPI,PINK1,CD2AP,CHMP1B,FOXO1,TUBB,RAB6C,PFN1,VPS4A,LAMP2,MAT2A,GAN,CARM1,ATAD3A,TRAF2,CAP2,ROCK1,ARPC5,WASL,KRT18,FAM114A1,GPI,MOB1B,REPS1,XPO1,ARHGEF1,PKN1,ETF1,EXOC2,SPAG9,FN3KRP,PACSIN2,MCM2,GIT1,TARDBP,PSMC3,ABCF1,DNM1,SAR1A,MPZL1,SHANK2,AP3B1,CAP1,IQGAP1,CHMP2A,BAG6,SOAT1,CLUH,PPP3CB,NCOR2,RHEB,WIPF1,FTSJ1,PRMT5,AKT1,ARPC2,TSR3,AP3D1,CASP8,MVP,EIF2S3,TANK,PYCARD,PER1,TUBB4A,BUB1,PXN,UBE2D2,SEC23B,VHL,PRDX5" -1.469437187 -0.286225035 451 1677 BENZOATE DEGRADATION VIA COA LIGATION BENZOATE DEGRADATION VIA COA LIGATION 0.000120963 0.000264869 -1 "SARS,AARS,GFPT1,APP,GARS,XPOT,CTH,PDIA4,TARS,GYS1,ASS1,GALT,HSPA5,ATIC,ENO2,GOT1,ATP6V1A,CNDP2,ATP6V1B2,MTHFD1,NARS,PRKAR1A,ATP6V1C1,PGD,PFKM,TUBB3,NDUFA4,PRKAR1B,GDI1,PPP1R7,ATP6V1E1,TUBB4B,PSMD9,IPO4,GAPDH,PFKL,FKBP1A,LARS,NEDD4L,GART,NAP1L1,ACSS2,BCAT1,HGH1,BAD,AKR1A1,GMPPB,PFKP,HSPA6,PGM1,MAP2K2,UGP2,EIF4EBP1,ADSL,SHMT1,IARS,PRPS2,CTPS1,ALDOC,PPA1,SRM,MYO1E,UBA1,AHCY,CUL4B,IPO5,NADSYN1,EEF2,ISYNA1,PDIA3,NAP1L4,PRKAA2,TUBA4A,PYCRL,HSPH1,NUTF2,SDSL,GDI2,TSR1,DSTN,GSK3A,EIF2B2,NPEPPS,PSMD11,IPO7,ENO1,CCT5,HSP90AA1,POLR3B,CAD,RRM2,EIF2B5,CCT8,DNM1L,NUP62,PYGB,STIP1,PPME1,ATF2,ARPC4,EIF4A1,DARS,ACTB,ACACA,ACAT2,PPID,YWHAZ,EGFR,PRDX2,NOTCH2,EIF4A2,ADK,HMGCS1,ARPC3,HSP90AB1,OLA1,DDI2,LSM1,CCT7,FN3K,MMS19,YWHAQ,PPIA,PPP2CB,AKR1D1,KRI1,NFKB1,CCT4,EIF6,PSMD7,NSFL1C,CCT3,PEA15,KPNB1,TALDO1,CTPS2,EIF2S2,PLS3,IRF3,HSPA1B,MAPK1,ATG5,GPN1,ATP6V1D,UBQLN1,TCP1,MYL1,CSNK1D,PFKFB2,NOTCH3,TKT,PNPO,FBXO6,ARFGEF2,PPP6C,TNPO2,PLS1,CSE1L,DNAJC21,TUBA1A,BTF3L4,FARSA,UBE3C,RAD23B,ARF4,TUBB6,VCP,MPI,TUBB,MAT2A,ARPC5,WASL,GPI,MOB1B,XPO1,ETF1,FN3KRP,MCM2,PSMC3,ABCF1,SAR1A,CLUH,PPP3CB,PRMT5,AKT1,ARPC2,EIF2S3" -1.957815846 -0.401004285 187 555 PROSTAGLANDIN FORMATION FROM ARACHIDONATE PROSTAGLANDIN FORMATION FROM ARACHIDONATE 0.0001155 0.000264869 -1 "SDCBP,SARS,MAP1LC3A,AARS,HSPB1,GFPT1,APP,F10,GARS,CTH,PDIA4,METAP2,TARS,PDCD6IP,GALT,HSPA5,ATIC,ACY1,ENO2,SLC3A2,GOT1,ATP6V1A,ATP6V1B2,MTHFD1,RPS6KA3,NARS,PRKAR1A,ATP6V1C1,PGD,PFKM,TUBB3,NDUFA4,PRKAR1B,GDI1,ATP6V1E1,TUBB4B,PSMD9,IPO4,GAPDH,GSTM3,PFKL,IKBKB,PRDX6,FKBP1A,LARS,NEDD4L,TGM2,GART,ACSS2,PDXDC1,BCAT1,AHSA1,GSTO1,SRRM2,AKR1A1,GMPPB,RAB3GAP1,CDK6,PFKP,HSPA6,PGM1,BAG3,UGP2,GSTM1,PEBP1,ADSL,SHMT1,IARS,CTPS1,ARFGAP1,PPA1,UBA1,AHCY,MAPRE1,EEF2,ISYNA1,EPRS,PDIA3,FKBP4,PRKAA2,TUBA4A,CBR3,HSPH1,NUTF2,HSPA4,GDI2,TSR1,DSTN,GSTCD,GSK3A,PTGES3,EIF2B2,ISG15,NPEPPS,PSMD11,MARS,ENO1,ALDOA,CCT5,HSP90AA1,POLR3B,DCTN1,CAD,HNRNPM,ARRB2,RRM2,DERA,CCT8,ABCE1,DNM1L,PYGB,STIP1,EPS8L2,ATF2,EIF4A1,GSTP1,PCBP1,DARS,ACTB,ACACA,ACAT2,PPID,YWHAZ,EGFR,HLA-B,LPIN3,CALR,CBR1,PRDX2,STAT1,HINT1,SH3GLB1,EIF4A2,ADK,ARL1,COPS7A,HMGCS1,HSP90AB1,SLC1A5,UBE2O,ARMT1,OLA1,XPO7,CCT7,PKM,MSN,AKR1B1,MMS19,YWHAQ,CASP7,PPIA,PPP2CB,AKR1D1,ZFP36,KRI1,DVL2,NFKB1,HECW2,NME7,CCT4,YWHAG,ALDH16A1,AIP,EIF6,ABCG1,CCT3,CASP3,KPNB1,TALDO1,CTPS2,METAP1,STUB1,PLS3,HSPA1B,MAPK1,ATG5,UBQLN1,RAB3GAP2,MYL1,CSNK1D,GNB1L,TKT,HDAC6,DNAJC7,FBXO6,PPP6C,TNPO2,PLS1,CSE1L,PIP4K2A,TUBA1A,BTF3L4,OGFR,LDLR,CDC37,ITGB3,MYH9,FARSA,COPS5,CHCHD2,ARF4,TUBB6,VCP,MPI,CD2AP,TUBB,RAB6C,LPIN1,LSM3,DCUN1D1,MAT2A,CARM1,ATAD3A,TRAF2" -1.645434058 -0.329835722 214 804 LEUKOTRIENE METABOLISM LEUKOTRIENE METABOLISM 0.000109457 0.000264869 -1 "PGRMC2,SDCBP,SARS,MAP1LC3A,SQSTM1,AARS,GFPT1,TBC1D15,APP,F10,GARS,XPOT,CTH,LAMP1,PDIA4,TARS,LGALS3BP,GYS1,SNX2,PDCD6IP,ASS1,RRAGA,GALT,HSPA5,ATIC,TNIP1,ACY1,ENO2,SLC3A2,GALE,GOT1,CALCOCO2,ATP6V1A,CNDP2,ATP6V1B2,MTHFD1,RPS6KA3,NARS,PRKAR1A,ATP6V1C1,PAICS,PGD,PFKM,PGK1,HUWE1,UBE2V1,TUBB3,NDUFA4,PRKAR1B,GDI1,EIF2A,IMPDH2,PPP1R7,NDRG1,ATP6V1E1,TUBB4B,IPO4,GAPDH,PRDX1,GSTM3,PFKL,NAMPT,IKBKB,IFRD2,PRDX6,FKBP1A,LARS,NEDD4L,TGM2,GART,NAP1L1,BLMH,ACSS2,PDXDC1,COTL1,BCAT1,AHSA1,GSTO1,AKR1A1,GMPPB,RAB3GAP1,CDK6,PFKP,HSPA6,PGM1,MAP2K2,BAG3,UGP2,GSTM1,PEBP1,SHMT1,IARS,CTPS1,ARFGAP1,PPA1,SRM,MYO1E,SPG20,ABHD14B,PSME1,UBA1,TIMP2,ARMC6,AHCY,MAPRE1,IPO5,EEF2,ISYNA1,EPRS,PDIA3,FUT11,NAP1L4,PRKAA2,VTA1,TUBA4A,CBR3,PYCRL,HSPH1,PARK7,NUTF2,HSPA4,SDSL,GDI2,GTPBP2,NAA15,TSR1,DSTN,NAA50,GSTCD,SPRY2,DBNL,MRPS17,PTPN11,PTGES3,EIF2B2,ISG15,NPEPPS,PSMD11,MARS,IPO7,DYRK1A,ENO1,ALDOA,PRKCI,CCT5,HSP90AA1,POLR3B,DCTN1,CAD,HNRNPM,MYH10,RRM2,DERA,EIF2B5,CCT8,ABCE1,PIK3R1,PYGB,STIP1,EPS8L2,ATF2,EIF4A1,HGS,GSTP1,TNIK,PCBP1,DARS,ACTB,ACACA,ACAT2,AK1,PPID,YWHAZ,EGFR,HLA-B,PLAA,FHIT,CALR,CBR1,CAND1,PRDX2,STAT1,CDK5,HINT1,SH3GLB1,EIF4A2,ADK,MLLT4,ARL1,HMGCS1,ARPC3,HSP90AB1,SLC1A5,UBE2O,TSC2,LTA4H,ARMT1,OLA1,XPO7,IPO13,TPP2,RNASEH2A,LSM1,CCT7,SNX3,PKM,MSN,VCL,MMS19,YWHAQ,NT5C2,CKS1B,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,GCLC,DVL2,HECW2,CCT4,YWHAG,ALDH16A1,EIF6,PSMD7,ABCG1,SLC35F6,CLDN12,NSFL1C,CCT3,DDX3X,KPNB1,TALDO1,CTPS2,CLK1,EIF2S2,PLS3,HSPA1B,PAAF1,MAPK1,CAPZA2,ATG5,DRG2,CARHSP1,GPN1,PSMF1,CAB39,ATP6V1D,UBQLN1,THADA,TCP1,RAB3GAP2,MYL1,CSNK1D,GNB1L,TKT,NOM1,KPNA3,FBXO6,ARHGAP17,SETD1B,FERMT2,PPP6C,COPA,TNPO2,PLS1,CSE1L,IMPDH1,UBA5,PIP4K2A,TUBA1A,BTF3L4,OGFR,LDLR,CDC37,DTD1,PSMD6,PFDN4,MYH9,PPAN,FARSA,COPS5,CHCHD2,UBE3C,ARF4,TUBB6,VCP,ARRB1,MPI,TUBB,LSM3,GET4,DCUN1D1,LAMP2,MAT2A,TRAF2,WASL,GPI,MOB1B,SLC27A1,XPO1,ETF1,MCM2,KDELR3,PSMC3,EIF5B,TUBGCP3,IQGAP1,BAG6,TCEA1,CLUH,IDE,BAIAP2,PPP3CB,RABAC1,EXOC6,EXOC1,FTSJ1,PRMT5,PRUNE,AKT1,CCDC22,EIF2S3,XPO5,SBDS,TUBB4A,BUB1,UBE2D2,SEC23B,VHL,PRDX5" -1.50862019 -0.296727747 331 1235 FATTY ACID ACTIVATION FATTY ACID ACTIVATION 0.000133672 0.000264869 -1 "PGRMC2,GFPT1,APP,XPOT,PDIA4,RRAGA,GALT,HSPA5,ENO2,CALCOCO2,ATP6V1A,ATP6V1B2,PAICS,PFKM,ATOX1,TUBB3,NDUFA4,NDRG1,TUBB4B,IPO4,GAPDH,PFKL,LARS,GART,GMPPB,PFKP,HSPA6,PGM1,CTPS1,SPG20,AHCY,EEF2,PDIA3,PRKAA2,TUBA4A,PYCRL,HSPH1,HSPA4,SDSL,EIF2B2,IPO7,HSP90AA1,CAD,RRM2,EIF2B5,CCT8,PYGB,EIF4A1,DARS,ACTB,ACACA,PPID,YWHAZ,EGFR,EIF4A2,ADK,HSP90AB1,SLC1A5,OLA1,MMS19,YWHAQ,NT5C2,HECW2,PSMD7,ABCG1,CTPS2,EIF2S2,PLS3,HSPA1B,GPN1,ATP6V1D,CSNK1D,NOM1,PPP6C,TNPO2,PLS1,CSE1L,TUBA1A,PFDN4,FARSA,COPS5,TUBB6,VCP,TUBB,GET4,MAT2A,WASL,GPI,MOB1B,SLC27A1,XPO1,MCM2,PSMC3,TUBGCP3,CLUH,PPP3CB,RABAC1" -1.777419256 -0.383954007 97 292 CARBON FIXATION CARBON FIXATION 0.000117716 0.000264869 -1 "SARS,MAP1LC3A,SQSTM1,AARS,APP,GARS,PDIA4,TARS,ASS1,HSPA5,ATIC,ABL2,ENO2,PEPD,ATP6V1B2,MTHFD1,RPS6KA3,ASNS,IDH1,NARS,PRKAR1A,ATP6V1C1,MARK2,GLE1,PGD,PFKM,PGK1,HUWE1,TUBB3,NDUFA4,PRKAR1B,GDI1,NDRG1,ATP6V1E1,TUBB4B,GAPDH,PRDX1,CHUK,PFKL,IKBKB,FKBP1A,LARS,MET,NEDD4L,GART,ACSS2,EPHA2,LDHB,AMDHD2,AHSA1,GSTO1,GMPPB,PFKP,HSPA6,ADSS,PGM1,MAP2K2,BAG3,UGP2,HARS,SHMT1,IARS,CTPS1,ALDOC,PPA1,UBA1,MDP1,AHCY,CUL4B,MAPRE1,IPO5,EEF2,ISYNA1,FGFR1,PDIA3,PRKAA2,TUBA4A,HSPH1,NUTF2,HSPA4,GDI2,NIF3L1,ATG3,DSTN,LSM14A,OTUD5,GSK3A,PTGES3,EIF2B2,ISG15,NPEPPS,IPO7,MAP2K1,ENO1,ALDOA,CCT5,HSP90AA1,CAD,MVK,ARRB2,MYH10,RRM2,CCT8,NUP62,USP9X,BIN1,PYGB,STIP1,PPME1,ATF2,UBQLN2,FNTB,ARAF,EIF4A1,TNIK,ACTB,ACAT2,YWHAZ,EGFR,WDR1,HLA-B,LPIN3,CALR,PRDX2,NOTCH2,HINT1,EIF4A2,LDHA,HMGCS1,HSP90AB1,CCDC6,CKB,OLA1,IKBKAP,PRKCZ,LSM1,PKM,MSN,AKR1B1,MMS19,YWHAQ,CASP7,PTK2,PPIA,COPB1,GCLC,DVL2,ABCC3,NFKB1,ARHGDIA,HECW2,TP53RK,CCT4,YWHAG,CCT3,NAGK,CASP3,KPNB1,KIF23,BMPR1A,CTPS2,PLS3,TNFRSF10D,MAP3K3,DPH2,HSPA1B,MAPKAPK3,MAPK1,ATG5,TRAF3IP1,GLO1,UBQLN1,TCP1,CSNK1D,RC3H1,MST1R,NOTCH3,TKT,HDAC6,FBXO6,CAMKK2,PLS1,CSE1L,DNAJC21,NFIC,NDUFB8,TUBA1A,BTF3L4,BCAR3,CDC37,PFDN4,SNX9,MYH9,ISCU,FARSA,COPS5,MAP2K3,RAD23B,TUBB6,VCP,ARRB1,MPI,TUBB,LPIN1,MAT2A,GPI,XPO1,ETF1,MCM2,FAM122A,PSMC3,ABCF1,NDUFB1,CLUH,RELA,EXOC6,SDCCAG3,FTSJ1,AKT1,XPO5,TUBB4A,BUB1,PXN,VHL,PRDX5" -1.851608095 -0.373981234 225 703 ASPARTATE AND ASPARAGINE METABOLISM ASPARTATE AND ASPARAGINE METABOLISM 0.000108108 0.000264869 -1 "SDCBP,SARS,MAP1LC3A,SQSTM1,AARS,HSPB1,GFPT1,TBC1D15,APP,F10,GARS,XPOT,CTH,PDIA4,TARS,LGALS3BP,GYS1,PDCD6IP,ASS1,GALT,HSPA5,ATIC,ACY1,ENO2,SLC3A2,GALE,GOT1,RNF31,ATP6V1A,CNDP2,ATP6V1B2,MTHFD1,COPRS,RPS6KA3,IDH1,NARS,PRKAR1A,ATP6V1C1,PGD,PFKM,PGK1,HUWE1,UBE2K,UBE2V1,TUBB3,PRKAR1B,GDI1,IMPDH2,PPP1R7,NDRG1,ATP6V1E1,TUBB4B,IPO4,GAPDH,PFDN2,GSTM3,PFKL,NAMPT,IKBKB,PRDX6,FKBP1A,LARS,NEDD4L,TGM2,GART,NAP1L1,ACSS2,PDXDC1,BCAT1,SEC31A,APRT,AHSA1,GSTO1,SRRM2,AKR1A1,GMPPB,RAB3GAP1,PFKP,HSPA6,PGM1,MAP2K2,BAG3,UGP2,GSTM1,NFKBIE,SHMT1,IARS,FASN,CTPS1,ARFGAP1,PSEN2,PPA1,SRM,MYO1E,UBA1,ARMC6,AHCY,MAPRE1,IPO5,EEF2,ISYNA1,EPRS,PDIA3,NAP1L4,PLEC,PRKAA2,TUBA4A,PYCRL,HSPH1,NUTF2,HSPA4,SDSL,GDI2,NIF3L1,NAA15,TSR1,DSTN,GSTCD,CLN3,OTUD5,PTGES3,EIF2B2,ISG15,NPEPPS,GCDH,PSMD11,MARS,MAP2K1,ENO1,ALDOA,PRKCI,CCT5,HSP90AA1,TRIP13,POLR3B,DCTN1,CAD,HNRNPM,ARRB2,MYH10,RRM2,DERA,DNM2,EIF2B5,CCT8,DNM1L,PIK3R1,PYGB,STIP1,PPME1,EPS8L2,ATF2,UBQLN2,ARPC4,ARAF,EIF4A1,GSTP1,TNIK,PCBP1,DARS,ASPSCR1,ACTB,ACACA,ACAT2,ALDH3B1,PPID,YWHAZ,EGFR,PI4K2A,HLA-B,PLAA,FHIT,CALR,CAND1,PRDX2,STAT1,CDK5,SH3GLB1,EIF4A2,ADK,PSMB7,ARL1,HMGCS1,ARPC3,TXN,HSP90AB1,SLC1A5,UBE2O,TSC2,CEP170,ARMT1,BABAM1,OLA1,VAC14,XPO7,MT-ND5,DDI2,IPO13,VASP,LSM1,CCT7,PKM,MSN,SFN,MMS19,YWHAQ,CASP7,CKS1B,ABCF3,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,GCLC,DVL2,NFKB1,ATP2B4,TP53RK,NME7,FAT1,CCT4,YWHAG,TFG,ALDH16A1,EIF6,PSMD7,SLC35F6,RARS,NSFL1C,CCT3,DDX3X,KPNB1,PSMA2,BMPR1A,TALDO1,CTPS2,SAT2,EIF2S2,STUB1,PLS3,TNFRSF10D,HSPA1B,PAAF1,MAPK1,CAPZA2,PARP4,ATG5,DRG2,GPN1,ASNA1,GPX1,ATP6V1D,UBQLN1,THADA,ASB1,DDX39A,TCP1,RAB3GAP2,MYL1,CSNK1D,GNB1L,TKT,NOM1,KPNA3,ILK,DNAJC7,UBE2V2,FBXO6,SETD1B,PPP6C,SLC7A5,COPA,EEF1E1,TNPO2,PLS1,CSE1L,IMPDH1,UBA5,DNAJC21,FUNDC2,PIP4K2A,TUBA1A,BTF3L4,OGFR,BCAR3,CDC37,PSMB2,PSMD6,PFDN4,MYH9,PPAN,IKBKG,UMPS,ZSWIM8,FARSA,COPS5,LCN2,TTC1,CHCHD2,UBE3C,RAD23B,ARF4,TUBB6,VCP,ARRB1,MPI,AIMP1,TUBB,LSM3,PSMA7,HDAC4,MAT2A,EIF3B,TRAF2,ARPC5,WASL,KRT18,GPI,MOB1B,KLC3,XPO1,ETF1,NUDCD3,MCM2,PSMC3,EIF5B,ABCF1,DNM1,MRM1,TCEA1,CLUH,RELA,IDE,PPP3CB,EXOC6,MAP3K7,FTSJ1,NUDT3,PRMT5,PRUNE,AKT1,ARPC2,TOM1L1,EIF2S3,PSMB3,XPO5,TANK,TUBB4A,BUB1,PXN,SEC23B,VHL,PRDX5,PRKAB2,TRAF4,PSMA1,ASL,TCEB2,PSMA5,KCMF1,ACTR2,ATXN10,GPX4,EIF2B3,AIMP2,UFL1" -1.506059292 -0.295333677 367 1331 DRUG METABOLISM - OTHER ENZYMES DRUG METABOLISM - OTHER ENZYMES 0.000124254 0.000264869 -1 "SDCBP,MAP1LC3A,APP,GARS,LGALS3BP,CRELD2,ATP6V1A,ATP6V1B2,PRKAG2,IDH1,PGD,PFKM,UPP1,HUWE1,TUBB3,GDI1,IMPDH2,TUBB4B,GAPDH,PFKL,NUDT5,SEC31A,AHSA1,GMPPB,PFKP,HSPA6,RNF19B,EIF4EBP1,HARS,FASN,CTPS1,ARFGAP1,AAMP,PSME1,AHCY,FGFR1,UCKL1,HPRT1,PRKAA2,TUBA4A,NAA50,SPRY2,PTPN11,NRBP1,EIF2B2,FYN,PSMD11,DOCK7,HSP90AA1,POLR3B,ARRB2,CCT8,ABCE1,PIK3R1,UGDH,ACTR1B,TNIK,ACTB,PPID,YWHAZ,EGFR,HLA-B,EIF4A2,HMGCS1,TSC2,CDA,BABAM1,PKM,SFN,LXN,ATXN3,PPP2CB,KRI1,GCLC,DVL2,NFKB1,TP53RK,ALDH16A1,EIF6,SHC1,KPNB1,BMPR1A,DDAH2,CTPS2,CLK1,TNFRSF10D,HSPA1B,PAAF1,MAPK1,ATG5,CARHSP1,GPN1,ASNA1,STMN1,CSNK1D,KPNA3,SH3KBP1,FBXO6,USP4,CSE1L,IMPDH1,TUBA1A,PLCG1,BCAR3,SNX1,PPAN,ISCU,COPS5,LCN2,PLEKHB2,TUBB6,VCP,ARRB1,TUBB,MAT2A,PTPRK,XPO1,ETF1,MCM2,PSMC3,EIF5B,BMPR2,BAG6,SOAT1,TCEA1,IDE,FTSJ1,AKT1,TUBB4A,SEC23B,VHL,FLRT2,PSMA1" -1.448320541 -0.300264522 133 474 AMINOSUGARS METABOLISM AMINOSUGARS METABOLISM 0.000115473 0.000264869 -1 "SDCBP,SARS,AARS,GFPT1,APP,GNPDA1,GARS,XPOT,CTH,PDIA4,TARS,GYS1,ASS1,GALT,HSPA5,ATIC,ENO2,POC5,GOT1,ATP6V1A,CNDP2,ATP6V1B2,MTHFD1,NARS,PRKAR1A,ATP6V1C1,PGD,PFKM,PGK1,TUBB3,NDUFA4,PRKAR1B,GDI1,PCYT2,PPP1R7,ATP6V1E1,TUBB4B,PSMD9,IPO4,GAPDH,USP14,CTSL,PFKL,IKBKB,FKBP1A,VPS4B,LARS,ACLY,NEDD4L,GART,NAP1L1,ACSS2,AMDHD2,BCAT1,HGH1,IPO9,AKR1A1,IMPA1,PEG10,PGM3,GMPPB,PFKP,HSPA6,PGM1,MAP2K2,BAG3,UGP2,ADSL,SHMT1,IARS,PRPS2,FASN,CTPS1,ALDOC,PPA1,SRM,MYO1E,UBA1,MDP1,AHCY,IPO5,NADSYN1,EEF2,ISYNA1,EPRS,PDIA3,NAP1L4,PRKAA2,TUBA4A,PYCRL,HSP90B1,HSPH1,NUTF2,HSPA4,SDSL,GDI2,NIF3L1,TSR1,DSTN,DBNL,GSK3A,EIF2B2,NPEPPS,PSMD11,MARS,IPO7,ENO1,ALDOA,CCT5,HSP90AA1,TRIP13,POLR3B,CAD,ECM29,RRM2,EIF2B5,CCT8,BIRC6,DNM1L,PYGB,STIP1,ATF2,ARPC4,EIF4A1,DARS,ACTB,ACACA,ACAT2,PPID,YWHAZ,EGFR,HLA-B,PRDX2,EIF4A2,ADK,HMGCS1,ARPC3,HSP90AB1,UBR4,CEP170,OLA1,PSMB6,TPP2,PSMB8,LSM1,CCT7,PKM,MMS19,YWHAQ,CKS1B,ABCF3,GNPNAT1,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,GCLC,WIPI2,NFKB1,CCT4,EIF6,PSMD7,NSFL1C,CCT3,PEA15,NAGK,KPNB1,PSMA2,TALDO1,CTPS2,EIF2S2,PLS3,IRF3,HSPA1B,MAPK1,ATG5,GPN1,ASNA1,ATP6V1D,UBQLN1,KIF1B,DDX39A,HELZ,TCP1,MYL1,CSNK1D,TKT,PNPO,FBXO6,ARFGEF2,PSMB1,PPP6C,COPA,TNPO2,PLS1,USP4,CSE1L,UBA5,DNAJC21,TUBA1A,BTF3L4,PSMB2,PSMD6,PFDN4,UMPS,FARSA,UBE3C,RAD23B,ARF4,TUBB6,VCP,MPI,TUBB,LSM3,PSMA7,VPS4A,MAT2A,GAN,CAP2,ARPC5,WASL,GPI,MOB1B,XPO1,ETF1,MCM2,PSMC3,SAR1A,CAP1,CLUH,PPP3CB,EXOC6,INPPL1,PRMT5,PRUNE,AKT1,ARPC2,EIF2S3,PSMB3,XPO5,LCMT1,TUBB4A,SEC23B,PRDX5,PRKAB2,PSMA1,ASL,KCMF1,COG3,ACTR2,PSMB9,EIF2B3" -1.773172671 -0.355410215 253 809 TYROSINE METABOLISM TYROSINE METABOLISM 0.00010725 0.000264869 -1 "PGRMC2,SARS,MAP1LC3A,SQSTM1,AARS,GFPT1,TBC1D15,APP,F10,GARS,XPOT,CTH,LAMP1,PDIA4,TARS,LGALS3BP,GYS1,SNX2,PDCD6IP,ASS1,NDST1,YARS,GALT,HSPA5,ATIC,TNIP1,ACY1,ENO2,SLC3A2,GALE,WARS,GOT1,CALCOCO2,ATP6V1A,CNDP2,ATP6V1B2,MTHFD1,RPS6KA3,NARS,PRKAR1A,ATP6V1C1,PGD,PFKM,HUWE1,UBE2V1,TUBB3,PRKAR1B,GDI1,EIF2A,IMPDH2,PPP1R7,NDRG1,ATP6V1E1,TUBB4B,PSMD9,IPO4,GAPDH,PRDX1,GSTM3,CTSL,PFKL,IKBKB,FAH,IFRD2,PRDX6,FKBP1A,VPS4B,LARS,NEDD4L,TGM2,GART,NAP1L1,BLMH,ACSS2,PDXDC1,LDHB,BCAT1,IPO9,APRT,AHSA1,GSTO1,SRRM2,AKR1A1,GMPPB,RAB3GAP1,CDK6,PFKP,HSPA6,PGM1,MAP2K2,BAG3,NAE1,UGP2,GSTM1,EIF4EBP1,ADSL,HARS,SHMT1,IARS,FASN,CTPS1,ARFGAP1,PPA1,SRM,MYO1E,XPNPEP1,ABHD14B,PSME1,UBA1,TIMP2,ARMC6,AHCY,IPO5,EEF2,ISYNA1,EPRS,PDIA3,NAP1L4,PRKAA2,VTA1,TUBA4A,PYCRL,HSP90B1,HSPH1,PARK7,NUTF2,HSPA4,SDSL,GDI2,GTPBP2,KIF5B,NIF3L1,NAA15,TSR1,NCK1,DSTN,NAA50,GSTCD,RIN1,DBNL,MRPS17,CLN3,PTPN11,PTGES3,EIF2B2,ISG15,NPEPPS,PSMD11,MARS,DYRK1A,ENO1,UBE2M,ALDOA,PRKCI,CCT5,HSP90AA1,TRIP13,POLR3B,DCTN1,CAD,HNRNPM,ARRB2,MYH10,WWP2,RRM2,DERA,EIF2B5,CCT8,ABCE1,GPSM1,DNM1L,PIK3R1,UGDH,PYGB,STIP1,EPS8L2,ATF2,UBQLN2,EIF4A1,UBE2R2,GSTP1,ESD,WWC1,TNIK,PCBP1,DARS,ASPSCR1,ACTB,ACACA,ACAT2,ALDH3B1,AK1,PPID,YWHAZ,EGFR,HLA-B,PLAA,FHIT,CRK,CALR,CAND1,PRDX2,STAT1,CDK5,HINT1,SH3GLB1,EIF4A2,LDHA,ADK,MLLT4,ARL1,HMGCS1,HSP90AB1,SLC1A5,UBE2O,TSC2,ARMT1,OLA1,XPO7,IPO13,SORT1,TPP2,TSC22D3,SPINT2,LSM1,CCT7,SNX3,PKM,MSN,VCL,MMS19,YWHAQ,CKS1B,VBP1,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,GCLC,DVL2,NFKB1,HECW2,CCT4,YWHAG,ALDH16A1,EIF6,PSMD7,ABCG1,SLC35F6,CLDN12,NSFL1C,CCT3,CASP3,DDX3X,KPNB1,TALDO1,CTPS2,CLK1,EIF2S2,PLS3,HSPA1B,PAAF1,MAPK1,CAPZA2,ATG5,DRG2,CARHSP1,GPN1,PSMF1,CAB39,PPT1,ATP6V1D,UBQLN1,THADA,DDX39A,TCP1,RAB3GAP2,MYL1,CSNK1D,GNB1L,TKT,NOM1,FBXO6,SETD1B,FERMT2,PPP6C,COPA,TNPO2,PLS1,CSE1L,IMPDH1,UBA5,DNAJC21,PIP4K2A,GIPC1,TUBA1A,CHST11,BTF3L4,OGFR,PLCG1,BCAR3,DTD1,PSMD6,PFDN4,MYH9,PPAN,IKBKG,FARSA,COPS5,LCN2,CHCHD2,UBE3C,CDC34,RAD23B,ARF4,TUBB6,VCP,ARRB1,MPI" -1.414981746 -0.276739716 320 1446 BETA-ALANINE METABOLISM BETA-ALANINE METABOLISM 0.000117661 0.000264869 -1 "SARS,MAP1LC3A,AARS,GFPT1,TBC1D15,APP,GARS,XPOT,CTH,PDIA4,TARS,LGALS3BP,GYS1,ASS1,GALT,HSPA5,ATIC,ENO2,GALE,GOT1,ATP6V1A,CNDP2,ATP6V1B2,MTHFD1,RPS6KA3,NARS,PRKAR1A,ATP6V1C1,PGD,PFKM,HUWE1,TUBB3,PRKAR1B,GDI1,IMPDH2,PPP1R7,ATP6V1E1,TUBB4B,SMS,IPO4,GAPDH,PFKL,IFRD2,FKBP1A,LARS,NEDD4L,GART,NAP1L1,ACSS2,BCAT1,PPP1R13L,AKR1A1,GMPPB,PFKP,HSPA6,PGM1,MAP2K2,UGP2,SHMT1,IARS,CTPS1,PPA1,SRM,MYO1E,ABHD14B,UBA1,TIMP2,AHCY,IPO5,EEF2,ISYNA1,PDIA3,NAP1L4,PRKAA2,TUBA4A,PYCRL,HSPH1,PARK7,NUTF2,HSPA4,SDSL,GDI2,GTPBP2,TSR1,NCK1,DSTN,PTGES3,EIF2B2,NPEPPS,FYN,PSMD11,MARS,IPO7,ENO1,PRKCI,CCT5,HSP90AA1,POLR3B,CAD,PUS7,MYH10,RRM2,EIF2B5,CCT8,ABCE1,CMBL,PYGB,STIP1,EIF4A1,TNIK,DARS,ACTB,ACACA,ACAT2,PPID,YWHAZ,EGFR,HLA-B,PLAA,FHIT,CAND1,PRDX2,EIF4A2,ADK,HMGCS1,HSP90AB1,TSC2,OLA1,IPO13,LSM1,CCT7,MMS19,CKS1B,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,GCLC,TP53RK,CCT4,EIF6,PSMD7,SLC35F6,CLDN12,NSFL1C,CCT3,KPNB1,TALDO1,CTPS2,EIF2S2,PLS3,HSPA1B,PAAF1,MAPKAPK3,MAPK1,CAPZA2,ATG5,DRG2,GPN1,ATP6V1D,THADA,TCP1,MYL1,CSNK1D,TKT,NOM1,FBXO6,SETD1B,FERMT2,PPP6C,COPA,TNPO2,PLS1,CSE1L,IMPDH1,UBA5,TUBA1A,BTF3L4,PSMD6,MYH9,PPAN,UMPS,FARSA,UBE3C,ARF4,TUBB6,VCP,MPI" -1.785865758 -0.360574017 189 710 C21-STEROID HORMONE BIOSYNTHESIS AND METABOLISM C21-STEROID HORMONE BIOSYNTHESIS AND METABOLISM 0.000132328 0.000264869 -1 "PGRMC2,SARS,MAP1LC3A,AARS,APP,GARS,CTH,PDIA4,SNX2,NDST1,HSPA5,ATIC,ENO2,ATP6V1B2,MTHFD1,RPS6KA3,NARS,PGD,PFKM,EIF2A,GAPDH,PFKL,BLMH,ACSS2,BCAT1,SEC31A,AKR1A1,CDK6,PFKP,HSPA6,PGM1,UGP2,EIF4EBP1,HARS,IARS,PPA1,PSME1,UBA1,AHCY,EEF2,ISYNA1,PDIA3,PPP2R4,HSPH1,HSPA4,NAA15,TSR1,NAA50,DBNL,PTPN11,NPEPPS,HSP90AA1,ARRB2,CCT8,UGDH,PYGB,ATF2,EIF4A1,DARS,ACTB,ACAT2,YWHAZ,EIF4A2,ADK,MLLT4,HSP90AB1,OLA1,TPP2,SNX3,PKM,AKR1B1,AKR1D1,AKR7A2,EIF2S2,PLS3,AKR1C3,HSPA1B,PSMF1,CAB39,CSNK1D,FBXO6,PPP6C,PLS1,CSE1L,ARHGAP1,TMX2,CHST11,DTD1,LCN2,VCP,ARRB1,MPI,GPI,SLC27A1,ETF1,MCM2,BMPR2,IQGAP1,TCEA1,CLUH,EXOC6,PRMT5" -1.842431447 -0.395784684 102 308 STARCH AND SUCROSE METABOLISM STARCH AND SUCROSE METABOLISM 0.000125063 0.000264869 -1 "PGRMC2,SARS,AARS,GFPT1,APP,GARS,CTH,PDIA4,GYS1,GALT,HSPA5,ATIC,GYG1,ENO2,GOT1,ATP6V1A,ATP6V1B2,MTHFD1,NARS,PRKAR1A,PGD,PFKM,PGK1,HUWE1,TUBB3,PRKAR1B,PPP1R7,ATP6V1E1,TUBB4B,IPO4,GAPDH,PFKL,IKBKB,VPS4B,NEDD4L,GART,G6PD,ACSS2,BCAT1,CCS,AKR1A1,GMPPB,CDK6,PFKP,HSPA6,PGM1,BAG3,UGP2,EIF4EBP1,SHMT1,IARS,CTPS1,PPA1,UBA1,AHCY,ACO1,IPO5,EEF2,ISYNA1,PDIA3,PRKAA2,TUBA4A,PPP2R4,HSPH1,HSPA4,SDSL,SGTA,NAA15,TSR1,RPS6KA1,OTUD5,GSK3A,EIF2B2,NPEPPS,FYN,MARS,ALDOA,PRKCI,CCT5,HSP90AA1,CAD,DNM2,CCT8,DNM1L,UGDH,PYGB,STIP1,EIF4A1,HGS,DARS,ACTB,ACAT2,PPID,EGFR,CAND1,PRDX2,SH3GLB1,EIF4A2,ADK,TXN,HSP90AB1,ARMT1,OLA1,PKM,MMS19,VBP1,PPIA,PPP2CB,AKR1D1,ABCG1,CCT3,NAGK,TALDO1,CTPS2,EIF2S2,PLS3,MAP3K3,AP3M2,GBE1,HSPA1B,MAPK1,KIFAP3,GPN1,ATP6V1D,TCP1,MYL1,CSNK1D,FBXO6,PSMB1,PPP6C,COPA,TNPO2,PLS1,CSE1L,DNAJC21,GIPC1,TUBA1A,PFDN4,COPS5,TUBB6,VCP,MPI,TUBB,SIRT2,MAT2A,GPI,MOB1B,XPO1,MCM2,PSMC3,EIF5B,POMP,CLUH,AKAP1,PRMT5,TUBB4A,BCL2L12,CAPZB,SEC23B,PRKAB2" -1.984936082 -0.412839158 160 457 OMEGA-6 FATTY ACID METABOLISM OMEGA-6 FATTY ACID METABOLISM 0.000116009 0.000264869 -1 "PGRMC2,SARS,MAP1LC3A,SQSTM1,AARS,GFPT1,APP,GARS,XPOT,CTH,LAMP1,PDIA4,TARS,RRAGA,GALT,HSPA5,ATIC,ENO2,GOT1,CALCOCO2,ATP6V1A,ATP6V1B2,MTHFD1,NARS,PRKAR1A,ATP6V1C1,PAICS,PGD,PFKM,PGK1,HUWE1,UBE2V1,TUBB3,NDUFA4,PRKAR1B,GDI1,NDRG1,ATP6V1E1,TUBB4B,PSMD9,IPO4,GAPDH,PFKL,IFRD2,FKBP1A,LARS,NEDD4L,GART,ACSS2,BCAT1,GSTO1,SRRM2,AKR1A1,GMPPB,CDK6,PFKP,HSPA6,PGM1,BAG3,UGP2,ADSL,SHMT1,IARS,CTPS1,PPA1,SPG20,ABHD14B,UBA1,TIMP2,ARMC6,AHCY,MAPRE1,EEF2,ISYNA1,EPRS,PDIA3,PRKAA2,VTA1,TUBA4A,PYCRL,HSPH1,PARK7,NUTF2,HSPA4,SDSL,GDI2,GTPBP2,TSR1,DSTN,DBNL,MRPS17,CLN3,PTGES3,EIF2B2,NPEPPS,PSMD11,MARS,IPO7,DYRK1A,ENO1,ALDOA,CCT5,HSP90AA1,POLR3B,CAD,RRM2,EIF2B5,CCT8,DNM1L,PYGB,STIP1,ATF2,EIF4A1,HGS,TNIK,DARS,ACTB,ACACA,ACAT2,AK1,PPID,YWHAZ,EGFR,HLA-B,CALR,PRDX2,STAT1,CDK5,HINT1,EIF4A2,ADK,HMGCS1,HSP90AB1,SLC1A5,OLA1,RNASEH2A,CCT7,MSN,VCL,MMS19,YWHAQ,NT5C2,PPIA,PPP2CB,AKR1D1,KRI1,HECW2,CCT4,YWHAG,EIF6,PSMD7,ABCG1,CLDN12,CCT3,DDX3X,KPNB1,TALDO1,CTPS2,CLK1,EIF2S2,PLS3,HSPA1B,MAPK1,ATG5,GPN1,ATP6V1D,MYL1,CSNK1D,TKT,NOM1,FBXO6,FERMT2,PPP6C,TNPO2,PLS1,CSE1L,UBA5,TUBA1A,BTF3L4,CDC37,PFDN4,MYH9,FARSA,COPS5,ARF4,TUBB6,VCP,MPI,TUBB,RAB6C,GET4,LAMP2,MAT2A,WASL,GPI,MOB1B,SLC27A1,XPO1,MCM2,PSMC3,SAR1A,TUBGCP3,BAG6,CLUH,IDE,BAIAP2,PPP3CB,RABAC1,EXOC1,FTSJ1,PRMT5,CCDC22,EIF2S3,TUBB4A,UBE2D2,SEC23B,VHL,PRDX5" -1.564744214 -0.314141787 218 782 PHYTANIC ACID PEROXISOMAL OXIDATION PHYTANIC ACID PEROXISOMAL OXIDATION 0.000119474 0.000264869 -1 "PGRMC2,SARS,MAP1LC3A,SQSTM1,GFPT1,APP,XPOT,LAMP1,PDIA4,RRAGA,GALT,HSPA5,ENO2,GALE,WARS,CALCOCO2,ATP6V1A,ATP6V1B2,NARS,PAICS,PFKM,HUWE1,UBE2V1,TUBB3,NDUFA4,GDI1,NDRG1,TUBB4B,IPO4,GAPDH,CTSL,PFKL,IFRD2,VPS4B,LARS,GART,LDHB,IPO9,APRT,AHSA1,GSTO1,GMPPB,CDK6,PFKP,HSPA6,PGM1,NAE1,FASN,CTPS1,SPG20,ABHD14B,UBA1,TIMP2,ARMC6,AHCY,EEF2,ISYNA1,EPRS,PDIA3,FKBP4,PRKAA2,VTA1,TUBA4A,PYCRL,HSP90B1,HSPH1,PARK7,HSPA4,SDSL,GDI2,GTPBP2,MRPS17,PTGES3,EIF2B2,NPEPPS,IPO7,DYRK1A,ENO1,UBE2M,ALDOA,HSP90AA1,CAD,ARRB2,WWP2,RRM2,EIF2B5,CCT8,ABCE1,PYGB,STIP1,ATF2,EIF4A1,UBE2R2,TNIK,DARS,ACTB,ACACA,AK1,PPID,YWHAZ,EGFR,HLA-B,CALR,STAT1,CDK5,HINT1,EIF4A2,LDHA,ADK,HSP90AB1,SLC1A5,OLA1,SPINT2,CCT7,MSN,VCL,MMS19,YWHAQ,NT5C2,COPB1,HECW2,CCT4,PSMD7,ABCG1,CLDN12,CCT3,DDX3X,KPNB1,CTPS2,CLK1,EIF2S2,PLS3,HSPA1B,MAPK1,ATG5,GPN1,ATP6V1D,DDX39A,CSNK1D,TKT,NOM1,FBXO6,FERMT2,PPP6C,TNPO2,PLS1,CSE1L,UBA5,TUBA1A,PFDN4,FARSA,COPS5,CDC34,RAD23B,TUBB6,VCP,ARRB1,TUBB,GET4,VPS4A,LAMP2,MAT2A,WASL,GPI,MOB1B,SLC27A1,XPO1,MCM2,PSMC3,RABIF,TUBGCP3,BAG6,CLUH,PPP3CB,RABAC1,EXOC1,FTSJ1,TOM1L1,EIF2S3" -1.610091255 -0.327281391 179 633 PENTOSE PHOSPHATE PATHWAY PENTOSE PHOSPHATE PATHWAY 0.000114718 0.000264869 -1 "RPTOR,SARS,SQSTM1,AARS,HSPB1,GFPT1,CLU,APP,GARS,CTH,PSAT1,PDIA4,TARS,LGALS3BP,ASS1,RRAGA,GALT,HSPA5,ATIC,ENO2,POC5,GOT1,ATP6V1A,ATP6V1B2,MTHFD1,ASNS,IDH1,NARS,PRKAR1A,ATP6V1C1,PGD,PFKM,PGK1,HUWE1,TUBB3,NDUFA4,PRKAR1B,GDI1,IMPDH2,ATP6V1E1,TUBB4B,IPO4,GAPDH,PGLS,PRDX1,USP14,KLC1,PFKL,FKBP1A,LARS,NEDD4L,GART,NAP1L1,G6PD,ACSS2,EPHA2,LDHB,BCAT1,AHSA1,GSTO1,AKR1A1,IMPA1,GMPPB,PFKP,HSPA6,PGM1,BAG3,UGP2,ADSL,HARS,SHMT1,IARS,PRPS2,CTPS1,ALDOC,PPA1,MYO1E,UBA1,AHCY,CUL4B,MAPRE1,EEF2,ISYNA1,PDIA3,RPAP3,NAP1L4,PRKAA2,VTA1,TUBA4A,HSPH1,NUTF2,HSPA4,SDSL,GDI2,SGTA,NIF3L1,ALAD,DSTN,ARFGAP3,PTPN11,PRPSAP2,GSK3A,PTGES3,EIF2B2,ISG15,NPEPPS,PSMD11,MARS,ENO1,ALDOA,CCT5,HSP90AA1,RPE,POLR3B,CAD,FBP1,RRM2,DERA,CCT8,ABCE1,BIN1,PYGB,STIP1,PPME1,ATF2,UBQLN2,EIF4A1,ESD,DARS,ACTB,ACACA,ACAT2,PPID,YWHAZ,EGFR,WDR1,HLA-B,CALR,CAND1,PRDX2,NOTCH2,HINT1,EIF4A2,LDHA,USP5,ADK,PSMB7,HMGCS1,HSP90AB1,CKB,KLC2,OLA1,PSMB6,DDI2,VASP,PSMB8,LSM1,CCT7,PKM,MSN,AKR1B1,MMS19,YWHAQ,CASP7,PTK2,CKS1B,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,NFKB1,ARHGDIA,HECW2,CCT4,EIF6,PSMD7,PPAT,NSFL1C,CCT3,NAA25,KPNB1,PSMA2,BMPR1A,TALDO1,CTPS2,SAT2,BRAF,PLS3,TNFRSF10D,GBE1,DPH2,HSPA1B,PAAF1,MAPK1,ATG5,GLO1,ATP6V1D,UBQLN1,KIF1B,ELP3,DDX39A,TCP1,MYL1,CSNK1D,NOTCH3,TKT,HDAC6,PNPO,PRPSAP1,FBXO6,PSMB1,COPA,TNPO2,PLS1,USP4,CSE1L,IMPDH1,UBA5,FUNDC2,NFIC,NDUFB8,TUBA1A,BTF3L4,UBXN1,DENR,PSMB2,PSMD6,PFDN4,SNX9,PPAN,FARSA,COPS5,UBE3C,MAP2K3,RAD23B,ARF4,TUBB6,VCP,MPI,NUDT9,TUBB,PSMA7,SIRT2,MAT2A,CAP2,TBCA,TMEM55A,GPI,XPO1,ETF1,EML4,PMF1,MCM2,PSMC3,ABCF1,CAP1,NDUFB1,CLUH,RELA,IDE,PPP3CB,FAM96A,FTSJ1,PRMT5,AKT1,ARPC2,SPG21,EIF2S3,ATP5J2,PSMB3,TUBB4A,BUB1,VHL,PRDX5,PSMA1,ASL,PSMA5,ACTR2" -1.928065047 -0.385185435 279 863 METHIONINE AND CYSTEINE METABOLISM METHIONINE AND CYSTEINE METABOLISM 0.000106508 0.000264869 -1 "SDCBP,SARS,MAP1LC3A,SQSTM1,AARS,HSPB1,GFPT1,NCOA4,APP,GARS,XPOT,CTH,PSAT1,PDIA4,TARS,GYS1,ASS1,YARS,GALT,HSPA5,ATIC,ACY1,ENO2,AHCYL2,GALE,WARS,GOT1,PEPD,ATP6V1A,CNDP2,ATP6V1B2,MTHFD1,ASNS,IDH1,NARS,PRKAR1A,ATP6V1C1,TSG101,PGD,OPTN,PFKM,PGK1,HUWE1,TPI1,UBE2V1,TUBB3,PRKAR1B,GDI1,PCYT2,EIF2A,IMPDH2,PPP1R7,NDRG1,ATP6V1E1,TUBB4B,PSMD9,IPO4,GAPDH,PFKL,NAMPT,IFRD2,FKBP1A,LARS,NUDT5,GOLM1,ACLY,NEDD4L,TGM2,GART,NAP1L1,ACSS2,LDHB,BCAT1,SEC31A,APRT,AHSA1,SRRM2,AKR1A1,GMPPB,PFKP,HSPA6,PGM1,MAP2K2,BAG3,UGP2,PEBP1,ADSL,SHMT1,IARS,GMPR2,CTPS1,ARFGAP1,TNFRSF10B,PPA1,DYNC1I2,SRM,XPNPEP1,TBC1D5,UBA1,DCTN2,ARMC6,AHCY,PHYHD1,CUL4B,IPO5,EEF2,TAGLN2,ISYNA1,EPRS,PDIA3,NAP1L4,KLC4,PRKAA2,SLC2A3,VTA1,MTRR,TUBA4A,PPP2R4,PYCRL,HSP90B1,HSPH1,NUTF2,HSPA4,SDSL,GDI2,SGTA,NIF3L1,TSR1,NCK1,DSTN,TOLLIP,NAA50,ARFGAP3,CLN3,PTGES3,EIF2B2,DYNC1H1,ISG15,NPEPPS,GCDH,FYN,PSMD11,STAT6,MARS,IPO7,ENO1,UBE2M,ALDOA,CCT5,HSP90AA1,POLR3B,DCTN1,CAD,MYH10,RRM2,EIF2B5,CCT8,ABCE1,GPSM1,CTU1,DNM1L,NUP62,PIK3R1,PYGB,STIP1,PPME1,PACSIN1,ATF2,UBQLN2,FNTB,ARAF,EIF4A1,PANK4,PPP2R5D,HGS,GSTP1,TNIK,PCBP1,DARS,ASPSCR1,ACTB,ACACA,ACAT2,LRRC47,PPID,YWHAZ,EGFR,HLA-B,MMP14,MMACHC,CALR,CAND1,PRDX2,NOTCH2,HINT1,EIF4A2,LDHA,ADK,HMGCS1,TXN,HSP90AB1,ENOPH1,S100A4,BPNT1,PPM1F,CKB,OLA1,PSMB6,DDI2,PSMB8,LSM1,CCT7,PKM,MSN,VCL,MMS19,YWHAQ,PTK2,PPP4R1,CKS1B,ABCF3,VBP1,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,DVL2,TRMT112,DCTN3,NFKB1,HECW2,TP53RK,NME7,CCT4,YWHAG,TFG,EIF6,PSMD7,ABCG1,RARS,SHC1,PPAT,NSFL1C,CCT3,DYNC1LI2,NUDC,KPNB1,PSMA2,KIF23,BMPR1A,STX12,TALDO1,CTPS2,CLK1,BRAF,EIF2S2,STUB1,PLS3,TNFRSF10D,MAP3K3,HSPA1B,BLM,PAAF1,MAPK1,CAPZA2,ATG5,PTS,DRG2,TRAF3IP1,GPN1,ASNA1,PPT1,ATP6V1D,UBQLN1,DDX39A,TCP1,MYL1,TIMP3,FLII,CSNK1D,WNT5B,NOTCH3,TKT,KPNA3,HDAC6,ILK,UBE2V2,SH3KBP1,FBXO6,ARFGEF2,PSMB1,PPP6C,COPA,EEF1E1,GMPR,UGGT1,TNPO2,PLS1,VCPIP1,CSE1L,IMPDH1,DNAJC21,GIPC1,TUBA1A,BTF3L4,EIF1AD,PLCG1,CBX3,BCAR3,STX3,DENR,ARHGEF10,PSMB2,PSMD6,PFDN4,FOXK1,MYH9,PPAN,IKBKG,UMPS,VPS25,ISCU,FNBP1,DCTN5,FARSA,COPS5,ATE1,ESCO2,TTC1,CHCHD2,AGAP3,MPP6,COL4A3BP,RAD23B,ARF4,TUBB6,VCP,MPI,AIMP1,TUBB,GET4,ZNF622,PSMA7,HDAC4,MAT2B,MAT2A,GAN,EIF3B,TRAF2,CAP2,ARFGAP2,GPI,MOB1B,PTPRK,XPO1,ETF1,CD55,ITPR3,NUDCD3,PACSIN2,MCM2,USP16,UBE4B,KDELR3,PSMC3,EIF5B,ABCF1,SAR1A,MRM1,FBXO21,CAP1,BAG6,PPP2R5B,SOAT1,SH3D19,CLUH,RELA,IDE,F8A1,PPP3CB,RABAC1,FTSJ1,PRMT5,PRUNE,AKT1,RPS14,ARPC2,AP3D1,EIF2S3,PSMB3,TUBB4A,CAPZB,UBE2E2,PXN,UBE2D2,SEC23B,VHL,PRDX5,PRKAB2,TRAF4,PSMA1,ASL,DDX52,PSMA5,COG3,ACTR2" -1.392021038 -0.271651139 407 1562 SELENOAMINO ACID METABOLISM SELENOAMINO ACID METABOLISM 0.000112397 0.000264869 -1 "PGRMC2,SDCBP,SARS,MAP1LC3A,SQSTM1,AARS,GFPT1,APP,GARS,XPOT,CTH,PSAT1,PDIA4,TARS,GYS1,ASS1,GALT,HSPA5,ATIC,ENO2,AHCYL2,WARS,GOT1,PEPD,ATP6V1A,CNDP2,ATP6V1B2,MTHFD1,IDH1,NARS,PRKAR1A,ATP6V1C1,PGD,PFKM,PGK1,HUWE1,TPI1,UBE2V1,TUBB3,PRKAR1B,GDI1,PCYT2,EIF2A,IMPDH2,ATP6V1E1,TUBB4B,PSMD9,IPO4,GAPDH,PFKL,NAMPT,FKBP1A,LARS,NEDD4L,GART,NAP1L1,ACSS2,BCAT1,SEC31A,APRT,AKR1A1,GMPPB,PFKP,HSPA6,PGM1,MAP2K2,UGP2,ADSL,SHMT1,IARS,CTPS1,PPA1,SRM,UBA1,AHCY,CUL4B,IPO5,EEF2,ISYNA1,EPRS,PDIA3,NAP1L4,PRKAA2,VTA1,MTRR,TUBA4A,PYCRL,HSPH1,NUTF2,HSPA4,SDSL,GDI2,TSR1,DSTN,ARFGAP3,PTGES3,EIF2B2,DYNC1H1,NPEPPS,GCDH,PSMD11,STAT6,MARS,IPO7,ENO1,UBE2M,CCT5,HSP90AA1,POLR3B,CAD,MYH10,RRM2,EIF2B5,CCT8,ABCE1,GPSM1,DNM1L,NUP62,PYGB,STIP1,ATF2,UBQLN2,ARAF,EIF4A1,HGS,DARS,ASPSCR1,ACTB,ACACA,ACAT2,LRRC47,PPID,YWHAZ,EGFR,HLA-B,MMACHC,CAND1,PRDX2,NOTCH2,HINT1,EIF4A2,ADK,HMGCS1,HSP90AB1,PPM1F,OLA1,PSMB6,DDI2,PSMB8,LSM1,CCT7,PKM,MMS19,YWHAQ,CKS1B,ABCF3,VBP1,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,DVL2,DCTN3,HECW2,TP53RK,CCT4,YWHAG,TFG,EIF6,PSMD7,SLC35F6,RARS,PPAT,NSFL1C,CCT3,KPNB1,PSMA2,TALDO1,CTPS2,BRAF,EIF2S2,PLS3,TNFRSF10D,MAP3K3,HSPA1B,BLM,PAAF1,MAPK1,ATG5,PTS,DRG2,TRAF3IP1,GPN1,ATP6V1D,UBQLN1,TCP1,MYL1,TIMP3,CSNK1D,NOTCH3,TKT,KPNA3,ILK,UBE2V2,SH3KBP1,FBXO6,ARFGEF2,PSMB1,PPP6C,SCLY,COPA,EEF1E1,UGGT1,TNPO2,PLS1,CSE1L,IMPDH1,DNAJC21,GIPC1,TUBA1A,BTF3L4,CBX3,BCAR3,LOXL4,PSMB2,PSMD6,PFDN4,FOXK1,MYH9,PPAN,IKBKG,UMPS,FARSA,COPS5,ATE1,AGAP3,COL4A3BP,RAD23B,ARF4,TUBB6,VCP,MPI,AIMP1,TUBB,GET4,ZNF622,PSMA7,MAT2B,MAT2A,EIF3B,CAP2,ARFGAP2,GPI,MOB1B,XPO1,ETF1,ITPR3,MCM2,UBE4B,KDELR3,PSMC3,EIF5B,SAR1A,CAP1,CLUH,RELA,IDE,F8A1,PPP3CB,PRMT5,PRUNE,AKT1,AP3D1,EIF2S3,PSMB3,TUBB4A,PXN,SEC23B,SEPHS2,PRDX5,PSMA1,ASL,DDX52,PSMA5,ACTR2,PSMB9,EIF2B3,AIMP2" -1.578114278 -0.313162776 289 994 PENTOSE AND GLUCURONATE INTERCONVERSIONS PENTOSE AND GLUCURONATE INTERCONVERSIONS 0.000150807 0.000293388 -1 "APP,ENO2,GOT1,ASNS,PGD,GDI1,FKBP1A,GSTO1,AKR1A1,HSPA6,ISYNA1,NUTF2,GDI2,CRADD,SGTA,PTGES3,EIF2B2,ENO1,EIF2B5,ABCE1,STIP1,HLA-B,CALR,HINT1,TXN,MSN,AKR1B1,AKR1D1,AKR7A2,ARHGDIA,CCT4,IST1,EIF2S2,AKR1C3,HSPA1B,CARHSP1,TKT,PSMA7,MAP3K7,EIF2S3,VHL,ASL,EIF2B3,FKBP2,DSP,DST,DEF6,UCHL3,EIF2S1,HSPA2,XYLB" -1.980562375 -0.484817761 51 104 VITAMIN B5 - COA BIOSYNTHESIS FROM PANTOTHENATE VITAMIN B5 - COA BIOSYNTHESIS FROM PANTOTHENATE 0.000161057 0.000307733 -1 "GARS,PPCS,ATP6V1B2,VPS4B,LDHB,HSPA6,ISYNA1,EIF2B2,ALDOA,CAD,PANK4,YWHAZ,EGFR,PANK2,LDHA,HSP90AB1,ARMT1,YWHAQ,LXN,DVL2,YWHAG,PEA15,HSPA1B,MAPK1" -2.075618507 -0.560452873 24 57 BIOPTERIN METABOLISM BIOPTERIN METABOLISM 0.000257169 0.000475532 -1 "SDCBP,SARS,CALCOCO1,HSPB1,APP,PSAT1,PRRC2C,GALT,AHCYL2,ATP6V1B2,PRKAR1A,PGD,PFKM,TPI1,TUBB3,PRKAR1B,TUBB4B,IPO4,PFKL,NAP1L1,APRT,AHSA1,GSTO1,GMPPB,CDK6,PFKP,HSPA6,PPA1,SRM,UBA1,AHCY,CUL4B,IPO5,NAP1L4,TUBA4A,HSPH1,HSPA4,SDSL,KIF5B,NIF3L1,DSTN,EIF2B2,PSMD11,IPO7,HSP90AA1,CAD,CCT8,STIP1,ZFP36L1,EIF4A1,HECTD1,PPP2R5D,WWC1,ASPSCR1,ACTB,ACACA,PPID,YWHAZ,CAND1,PRDX2,EIF4A2,HSP90AB1,PAWR,CCT7,YWHAQ,PPIA,PPP2CB,DVL2,NFKB1,MAP1B,EIF6,NSFL1C,CCT3,KPNB1,TALDO1,HSPA1B,PTS,ASB1,TKT,FBXO6,COPA,VCPIP1,TUBA1A,UBXN1,CDC37,PSMB2,MYH9,LATS1,COPS5,RAD23B,TUBB6,VCP,TUBB,DCUN1D1,MAT2A,TRAF2,CAP2,GPI,XPO1,AP3B1,CAP1,CHMP2A,PPP2R5B,TCEA1,NUDT3,AP3D1,CASP8,PSMB3,ZFP36L2,TUBB4A,PRDX5,ACTR2,UBR2" -1.518010803 -0.320587263 113 376 PORPHYRIN METABOLISM PORPHYRIN METABOLISM 0.000257765 0.000475532 -1 "GFPT1,APP,PDIA4,ENO2,ATP6V1B2,PFKM,TUBB3,NDUFA4,TUBB4B,IPO4,GAPDH,PFKL,NEDD4L,GMPPB,PLIN3,PFKP,HSPA6,PGM1,BAG3,NAE1,EIF4EBP1,HARS,CTPS1,KCNQ5,UBA1,TIMP2,STEAP3,MROH1,EEF2,FGFR1,GSPT1,PDIA3,TUBA4A,HSPH1,HSPA4,SDSL,ALAD,PTPN11,NPEPPS,MARS,MAP2K1,SH2D4A,ENO1,CCT5,CAD,ARRB2,MYH10,CCT8,ABCE1,CTU1,PIK3R1,UGDH,PPME1,PPP2R5D,HGS,DARS,ACTB,BLVRA,EGFR,PRDX2,CDK5,HSP90AB1,FAM84B,CCT7,PKM,UROD,PPP2CB,ATG7,CCT4,SHC1,CCT3,KPNB1,TALDO1,CTPS2,HSPA1B,MAPK1,ATG5,ATP6V1D,TCP1,CSNK1D,FBXO6,TNPO2,TUBA1A,PLCG1,PFDN4,MYH9,COPS5,LCN2,GSPT2,TUBB6,ARRB1,FOXO1,TUBB,MAT2A,EIF3B,GPI,XPO1,ETF1,MCM2,PSMC3,MPZL1,PPP2R5B,CLUH,CNN2,WIPF1,NUDT3,TUBB4A,SEC23B,VHL,FLRT2" -1.533495092 -0.324680975 110 361 C5-BRANCHED DIBASIC ACID METABOLISM C5-BRANCHED DIBASIC ACID METABOLISM 0.000446097 0.000809023 -1 "SARS,GFPT1,GALE,WARS,ATP6V1A,NARS,CTSL,VPS4B,LDHB,IPO9,APRT,AHSA1,CDK6,FASN,EPRS,HSP90B1,PTGES3,NPEPPS,DYRK1A,CAD,ARRB2,WWP2,CCT8,ABCE1,AK1,EGFR,CDK5,LDHA,CCT7,COPB1,CCT4,CCT3,DDX39A,CSNK1D" -1.818937967 -0.435197412 34 122 VITAMIN E METABOLISM VITAMIN E METABOLISM 0.000496032 0.00088459 -1 "SARS,MAP1LC3A,SQSTM1,GFPT1,APP,LAMP1,GALT,ENO2,GALE,WARS,ATP6V1A,ATP6V1B2,NARS,PGK1,HUWE1,UBE2V1,GDI1,GAPDH,CTSL,IFRD2,FKBP1A,VPS4B,NEDD4L,LDHB,IPO9,APRT,AHSA1,GSTO1,CDK6,HSPA6,BAG3,NAE1,FASN,ABHD14B,UBA1,TIMP2,ARMC6,AHCY,MAPRE1,EEF2,ISYNA1,EPRS,PRKAA2,VTA1,HSP90B1,HSPH1,PARK7,HSPA4,GDI2,GTPBP2,DBNL,MRPS17,PTGES3,NPEPPS,DYRK1A,ENO1,UBE2M,ALDOA,CAD,ARRB2,WWP2,CCT8,ABCE1,STIP1,ATF2,UBE2R2,HGS,TNIK,AK1,PPID,YWHAZ,EGFR,HLA-B,CALR,STAT1,CDK5,HINT1,LDHA,HSP90AB1,RNASEH2A,SPINT2,CCT7,MSN,VCL,YWHAQ,PPP2CB,COPB1,CCT4,CLDN12,CCT3,DDX3X,KPNB1,CLK1,HSPA1B,MAPK1,ATG5,CARHSP1,UBQLN1,DDX39A" -1.414202526 -0.29279255 99 480 PURINE METABOLISM PURINE METABOLISM 0.000517813 0.000908295 -1 "RPTOR,SDCBP,SARS,MAP1LC3A,CENPE,SQSTM1,PNP,AARS,HSPB1,GFPT1,APP,GARS,CYR61,CTH,LAMP1,PDIA4,TARS,LGALS3BP,GYS1,SNX2,TMEM59,RRAGA,LTBR,GALT,HSPA5,ATIC,ABL2,TNIP1,ENO2,LAMC1,WARS,GOT1,CALCOCO2,PEPD,ATP6V1A,ATP6V1B2,CORO1B,MTHFD1,RPS6KA3,PRKAG2,IDH1,NARS,PRKAR1A,ATP6V1C1,TSG101,MARK2,GLE1,PGD,PFKM,PGK1,HUWE1,UBE2K,TPI1,PDIA6,UBE2V1,TUBB3,NDUFA4,PRKAR1B,IMPDH2,PPP1R7,NDRG1,ATP6V1E1,TUBB4B,IPO4,CTTN,GAPDH,CHUK,PFDN2,ASAP1,PFKL,IKBKB,WDR77,FKBP1A,LARS,GOLM1,PREP,CRKL,ACLY,MET,NEDD4L,TGM2,GART,NAP1L1,G6PD,ACSS2,EPHA2,LDHB,COTL1,AMDHD2,BCAT1,SEC31A,APRT,AHSA1,GSTO1,SRRM2,AKR1A1,IMPA1,GMPPB,DIAPH2,PFKP,HSPA6,TMEM248,ADSS,PGM1,MAP2K2,BAG3,UGP2,EIF4EBP1,ADSL,SHMT1,IARS,GMPR2,KEAP1,FASN,CTPS1,ALDOC,FCHSD1,PPA1,SRM,MYO1E,SPG20,DPH1,TBC1D5,UBA1,GLMN,MDP1,AHCY,CUL4B,STEAP3,MAPRE1,IPO5,EEF2,ISYNA1,FGFR1,GSPT1,PDIA3,HPRT1,RPAP3,NAP1L4,PRKAA2,SLC2A3,TUBA4A,TWF1,PPP2R4,PYCRL,HSPH1,TRIP10,AMPD2,NUTF2,HSPA4,SDSL,GTPBP2,KIF5B,SYNJ2,SGTA,NIF3L1,ATG3,TSR1,NCK1,DSTN,SPRY2,LSM14A,NCOA6,OTUD5,GSK3A,PTGES3,EIF2B2,SH3GL1,DYNC1H1,ISG15,NPEPPS,FYN,PSMD11,STAT6,UBE2Z,MARS,IPO7,MAP2K1,DYRK1A,ENO1,PRKAA1,UBE2M,LASP1,ALDOA,PRKCI,CCT5,HSP90AA1,TRIP13,POLR3B,DCTN1,CAD,MVK,HNRNPM,ARRB2,PUS7,MYH10,RRM2,DNM2,EIF2B5,HSPBP1,NUDT2,CCT8,ABCE1,CLIC4,DNM1L,NUP62,PIK3R1,USP9X,DIAPH1,BIN1,PYGB,STIP1,PPME1,MAF1,PACSIN1,CHTF18,KDM6A,ATF2,ACTR1B,UBQLN2,ARPC4,FNTB,ARAF,EIF4A1,HECTD1,PPP2R5D,EDIL3,CD74,TNIK,PCBP1,DARS,CAST,ACTB,ACACA,ACAT2,ZYX,PPID,YWHAZ,EGFR,HLA-B,PLAA,FHIT,LPIN3,CRK,COPS2,CALR,CBR1,CAND1,PRDX2,NOTCH2,MOCS2,CDK5,HINT1,SH3GLB1,EIF4A2,LDHA,ACTR1A,ADK,MYL9,COPS7A,MIF,HMGCS1,ARPC3,TXN,HSP90AB1,CCDC6,CEP170,EIF5,BABAM1,OLA1,UBA7,VAC14,PIN4,XPO7,IKBKAP,DDI2,VASP,PRKCZ,SPINT2,LSM1,CCT7,SNX3,PKM,SNX12,MSN,SFN,VCL,AKR1B1,MMS19,YWHAQ,CASP7,PTK2,NFKBIB,ATXN3,NT5C2,ABCF3,VBP1,REPS2,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,GCLC,DVL2,TRMT112,ABCC3,PCDH1,WIPI2,WDR92,NFKB1,GMDS,SORBS2,ARHGDIA,HECW2,TP53RK,NME7,AAK1,CCT4,YWHAG,ALDH16A1,AIP,EIF6,PSMD7,ABCG1,DPYSL2,FRYL,SHC1,PPAT,NSFL1C,CCT3,DYNC1LI2,NAGK,SRXN1,CASP3,KPNB1,PSMA2,DSN1,KIF23,BMPR1A,TALDO1,CTPS2,CLK1,EIF2S2,STUB1,PLS3,TNFRSF10D,MAP3K3,HSPA1B,BLM,GAPVD1,PAAF1,MAPKAPK3,MAPK1,PPIL1,ATG5,COPS8,TRAF3IP1,GPN1,ASNA1,MFF,ATP6V1D,UBQLN1,APOB,DDX39A,TCP1,MYL1,CSNK1D,RC3H1,MST1R,NOTCH3,PAFAH1B2,TKT,MAP4K4,NOM1,HDAC6,ILK,DNAJC7,UBE2V2,APEX1,MYL12A,SH3KBP1,FBXO6,ABI1,MTMR6,ARFGEF2,CAMKK2,PPP6C,COPA,GMPR,EPS15,TNPO2,PLS1,USP4,CSE1L,IMPDH1,DNAJC21,ARHGAP1,SEPT9,NFIC,TEX264,GIPC1,TUBA1A,BTF3L4,LLGL2,PLCG1,BCAR3,SNX1,LDLR,CDC37,TWF2,PSMB2,PSMD6,SNX9,MYH9,PPAN,IKBKG,UMPS,FBXO7,ISCU,FNBP1,FARSA,COPS5,TTC1,GSPT2,CHCHD2,UBE3C,NELFE,MPP6,RAD23B,ARF4,TUBB6,VCP,ARRB1,MPI,PINK1,CD2AP,CSF1,TUBB,LPIN1,LSM3,PFN1,CLCN7,ZNF622,PSMA7,SIRT2,HDAC4,DCUN1D1,LAMP2,MAT2A,GAN,EIF3B,CAP2,CIRBP,RPAP2,ARPC5,WASL,KRT18,COPS4,GPI,MOB1B,REPS1,PTPRK,XPO1,MEPCE,ETF1,RTN4,EXOC2,TJP2,NUDCD3,PACSIN2,MCM2,TARDBP,FAM122A,PSMC3,EIF5B,RAPH1,DNM1,SAR1A,SHANK2,TUBGCP3,CAP1,URI1,CHMP2A,PPP2R5B,SOAT1,SH3D19,TCEA1,CLUH,RELA,IDE,PPP3CB,EXOC6,AKAP1,SDCCAG3,WIPF1,INPPL1,FAM96A,FTSJ1,PRMT5,PRUNE,AKT1,RPS14,ARPC2" -1.238114456 -0.239602487 504 2163 SQUALENE AND CHOLESTEROL BIOSYNTHESIS SQUALENE AND CHOLESTEROL BIOSYNTHESIS 0.000595451 0.001027633 -1 "PGRMC2,SARS,MAP1LC3A,AARS,APP,GARS,CTH,PDIA4,SPIRE1,SNX2,YARS,HSPA5,ATIC,ENO2,GOT1,ATP6V1A,CNDP2,ATP6V1B2,MTHFD1,NARS,PGD,PFKM,TUBB3,NDUFA4,EIF2A,TUBB4B,IPO4,GAPDH,PFKL,IKBKB,LARS,NEDD4L,BLMH,ACSS2,BCAT1,AKR1A1,GMPPB,PFKP,HSPA6,PGM1,BAG3,UGP2,EIF4EBP1,SHMT1,IARS,PPA1,PSME1,UBA1,AHCY,EEF2,EPRS,PDIA3,SLC2A3,TUBA4A,HSP90B1,HSPH1,HSPA4,NAA15,TSR1,NAA50,DBNL,PTPN11,NPEPPS,PMVK,IPO7,ENO1,ALDOA,HSP90AA1,CAD,MVK,ARRB2,ABCE1,PYGB,ATF2,EIF4A1,TNIK,DARS,ACTB,ACAT2,YWHAZ,EGFR,HLA-B,PRDX2,SLC38A1,EIF4A2,ADK,MLLT4,HSP90AB1,CTNNA2,PITPNA,KLC2,OLA1,FNBP4,TPP2,SPINT2,CCT7,SNX3,PKM,MMS19,CKS1B,ABCF3,PPIA,AKR1D1,NFKB1,HECW2,YWHAG,PPAT,CCT3,BMPR1A,EIF2S2,PLS3,HSPA1B,MAPK1,ATG5,PSMF1,CAB39,TRAPPC8,CSNK1D,ILK,FBXO6,SETD1B,TNPO2,STK32C,PLS1,CSE1L,FUNDC2,TUBA1A,CBX3,YAP1,CDC37,DTD1,MYH9,LATS1,FARSA,COPS5,TUBB6,VCP,MPI,TUBB,PSMA7,DCUN1D1,MAT2A,GPI,SLC27A1,XPO1,ETF1,MCM2,PSMC3,FBXO21,IQGAP1,SOAT1,TCEA1,CLUH,EXOC6,FTSJ1,PRMT5,SUGT1,AKT1,SBDS,TUBB4A,PXN,TRAF4,ASL,DDX52" -1.359171347 -0.275995411 164 639 PUTATIVE ANTI-INFLAMMATORY METABOLITES FORMATION FROM EPA PUTATIVE ANTI-INFLAMMATORY METABOLITES FORMATION FROM EPA 0.000952511 0.001617756 -1 "PGRMC2,SDCBP,SARS,HSPB1,APP,PDIA4,PFKM,NDUFA4,PSMD9,PFKL,NAMPT,FKBP1A,NEDD4L,COTL1,GSTO1,GMPPB,PFKP,HSPA6,PEBP1,MAPRE1,EEF2,ISYNA1,FKBP4,CBR3,HSPH1,HSPA4,PTGES3,NPEPPS,ALDOA,HSP90AA1,ARRB2,ABCE1,PIK3R1,STIP1,PPID,EGFR,HLA-B,CALR,CBR1,HINT1,COPS7A,ARPC3,HSP90AB1,LTA4H,SPINT2,MSN,AKR1B1,CASP7,PPIA,ZFP36,AIP,CASP3,STUB1,HSPA1B,UBQLN1,KPNA3,HDAC6,DNAJC7,FBXO6,CSE1L,UBA5,LDLR,COPS5,CHCHD2,VCP,CD2AP,DCUN1D1,CARM1,ATAD3A" -1.504959449 -0.329530267 69 252 VITAMIN B6 (PYRIDOXINE) METABOLISM VITAMIN B6 (PYRIDOXINE) METABOLISM 0.001115005 0.001864149 -1 "MAP1LC3A,GFPT1,APP,TUBB3,ATP6V1E1,TUBB4B,PDXK,HSPA6,PGM1,HSPH1,HSPA4,ACTB,YWHAZ,CAND1,HSP90AB1,YWHAQ,PPIA,HSPA1B,CSNK1D,PNPO,CSE1L,COPS5,TUBB6,TUBB" -1.773558552 -0.468274772 24 65 VITAMIN B1 (THIAMIN) METABOLISM VITAMIN B1 (THIAMIN) METABOLISM 0.001220703 0.002009465 -1 "GFPT1,GALT,HSPA5,ENO2,ATP6V1A,ATP6V1B2,NARS,ATP6V1C1,PGD,PFKM,HUWE1,TUBB3,TUBB4B,IPO4,GAPDH,PRDX1,PFKL,LARS,NEDD4L,GART,NAP1L1,BCAT1,SRRM2,GMPPB,PFKP,HSPA6,PGM1,UGP2,SHMT1,CTPS1,PPA1,SRM,AHCY,IPO5,EEF2,NAP1L4,TUBA4A,PYCRL,HSPH1,SDSL,DSTN,GSK3A,EIF2B2,ISG15,NPEPPS,PSMD11,IPO7,ENO1,ALDOA,CCT5,HSP90AA1,CAD,RRM2,CCT8,ABCE1,PYGB,STIP1,ARPC4,EIF4A1,ACTB,PPID,YWHAZ,EGFR,CAND1,PRDX2,SLC38A1,EIF4A2,ARPC3,HSP90AB1,PFDN1,BABAM1,PSMB6,PSMB8,CCT7,PKM,MMS19,YWHAQ,PPIA,PPP2CB,COPB1,NFKB1,NTPCR,HECW2,CCT4,YWHAG,EIF6,PSMD7,CCT3,KPNB1,PSMA2,CTPS2,STUB1,HSPA1B,MAPK1,CAPZA2,PPT1,ATP6V1D,TCP1,CSNK1D,HDAC6,APEX1,FBXO6,COPA,TUBA1A,BTF3L4,SH3RF1,PSMD6,PFDN4,COPS5,TUBB6,VCP,TUBB,PSMA7,MAT2A,CAP2,ARPC5,RMND5A,GPI,XPO1,MEPCE,MCM2,PSMC3,EIF5B,SAR1A,CAP1,CLUH,PPP3CB,PRUNE,AKT1,ARPC2,EIF2S3,PSMB3,PYCARD,TUBB4A,CAPZB,PRKAB2,PSMA1,ASL,ACTR2,PSMB9" -1.357648965 -0.279064404 140 527 GLYCOSYLPHOSPHATIDYLINOSITOL(GPI)-ANCHOR BIOSYNTHESIS GLYCOSYLPHOSPHATIDYLINOSITOL(GPI)-ANCHOR BIOSYNTHESIS 0.002080666 0.003373201 -1 "GARS,NARS,PFKM,IPO4,PFKL,PFKP,HSPA6,EEF2,HSPH1,HSPA4,HSP90AA1,YWHAZ,COPS2,HSP90AB1,YWHAQ,KPNB1,CLK1,MAP3K3,HSPA1B,ELP3,ARFGEF2,TRAF2,TARDBP,BAG6" -1.7153414 -0.455576503 24 63 PROSTAGLANDIN FORMATION FROM DIHOMO GAMA-LINOLEIC ACID PROSTAGLANDIN FORMATION FROM DIHOMO GAMA-LINOLEIC ACID 0.003084153 0.004925439 -1 "SARS,HSPB1,APP,PDIA4,NDUFA4,PSMD9,FKBP1A,GSTO1,MAPRE1,ISYNA1,FKBP4,HSPA4,PTGES3,ALDOA,HSP90AA1,ARRB2,ABCE1,STIP1,PPID,EGFR,HLA-B,CALR,HINT1,COPS7A,HSP90AB1,MSN,AKR1B1,CASP7,ZFP36,AIP,CASP3,STUB1,HSPA1B,UBQLN1,HDAC6,DNAJC7,FBXO6,COPS5,VCP,CD2AP,CARM1,ATAD3A,MCM2,URI1,FTSJ1,FRMD5,VHL,FKBP2,COPG1,COPS3,PIK3C2A,BCR" -1.530847964 -0.359514152 52 140 LINOLEATE METABOLISM LINOLEATE METABOLISM 0.003732836 0.005873727 -1 "PGRMC2,MAP1LC3A,APP,PDIA4,SNX2,CRELD2,HSPA5,ATIC,ABL2,EIF2A,GAPDH,PRDX6,BLMH,COTL1,HSPA6,BAG3,EIF4EBP1,HARS,PSME1,PDIA3,HSPA4,SGTA,NAA15,NAA50,DBNL,CLN3,PTPN11,HSP90AA1,DCTN1,ARRB2,PIK3R1,UGDH,PYGB,ATF2,PPID,YWHAZ,EGFR,USP5,MLLT4,COPS7A,HSP90AB1,TPP2,SPINT2,SNX3,PKM,CASP7,ZFP36,DVL2,YWHAG,CASP3,EIF2S2,MAPK1,PSMF1,ASNA1,CAB39,GPX1,UBQLN1,FBXO6,USP4,CSE1L,UBXN1,DTD1,XAGE1A,PSMB2,UMPS,COPS5,LCN2,VCP,ARRB1,AIMP1,ETF1,MCM2,ABCF1,CAP1,IQGAP1,BAG6,TCEA1,RELA,EXOC6,CASP8,SBDS,SEC23B,GPX4,EIF4EBP2,ALOX5" -1.393051655 -0.301303633 85 286 NITROGEN METABOLISM NITROGEN METABOLISM 0.003881541 0.006019201 -1 "XPOT,GOT1,PRKAG2,ASNS,PGD,HUWE1,TPI1,IPO4,IPO9,HSPA6,BAG3,CTPS1,IPO5,HSPH1,HSPA4,EIF2B2,IPO7,ALDOA,EIF2B5,CCT8,ABCE1,ACACA,EGFR,PLAA,CAND1,PRDX2,HSP90AB1,CA13,LSM1,AKR1B1,CCT4,CTPS2,MON2,HSPA1B,THADA,EXOC8,CSNK1D,TNPO2,CSE1L,PFDN4,KNTC1,COPS5,DCUN1D1,RTCB,XPO1,PSMC3,EXOC6,EXOC1,XPO5,ATXN10,SLC22A18,EIF2B3" -1.480614501 -0.339994356 52 166 SPHINGOLIPID METABOLISM SPHINGOLIPID METABOLISM 0.0043558 0.006658152 1 "BCL7C,TMPO,UGT8,CENPO,TCTN3,AKAP5,HMOX1,PON2" 1.836230737 0.603961936 8 19 TRIHYDROXYCOPROSTANOYL-COA BETA-OXIDATION TRIHYDROXYCOPROSTANOYL-COA BETA-OXIDATION 0.004740698 0.007144432 -1 "GFPT1,APP,GALT,ENO2,ATP6V1B2,UBE2V1,GAPDH,IFRD2,CDK6,HSPA6,ABHD14B,UBA1,TIMP2,AHCY,EEF2,ISYNA1,PRKAA2,VTA1,HSPH1,PARK7,HSPA4,GTPBP2,MRPS17,PTGES3,DYRK1A,ALDOA,CCT8,TNIK,PPID,YWHAZ,HLA-B,STAT1,CDK5,HSP90AB1,CLDN12,DDX3X,CLK1,HSPA1B,ATG5" -1.463196773 -0.335387658 39 170 PYRIMIDINE METABOLISM PYRIMIDINE METABOLISM 0.005021971 0.007463207 -1 "RPTOR,SDCBP,SARS,MAP1LC3A,CENPE,SQSTM1,PNP,AARS,HSPB1,GFPT1,APP,XPOT,LAMP1,PDIA4,TARS,LGALS3BP,GYS1,CRELD2,LTBR,GALT,HSPA5,ATIC,ABL2,TNIP1,ENO2,POC5,GOT1,CALCOCO2,PEPD,ATP6V1A,ATP6V1B2,CORO1B,MTHFD1,RPS6KA3,ASNS,IDH1,NARS,PRKAR1A,ATP6V1C1,TSG101,MARK2,GLE1,PGD,PFKM,PGK1,UPP1,HUWE1,UBE2K,TPI1,PDIA6,TXNRD1,UBE2V1,TUBB3,PRKAR1B,GDI1,IMPDH2,PPP1R7,NDRG1,ATP6V1E1,TUBB4B,IPO4,GAPDH,CASP4,CHUK,PFDN2,PFKL,IKBKB,WDR77,FKBP1A,VPS4B,LARS,NUDT5,GOLM1,PREP,ACLY,MET,NEDD4L,TGM2,GART,NAP1L1,G6PD,ACSS2,EPHA2,LDHB,AMDHD2,APRT,GSTO1,SRRM2,IMPA1,GMPPB,DIAPH2,PFKP,HSPA6,TMEM248,ADSS,PGM1,MAP2K2,RNF19B,BAG3,UGP2,SHMT1,IARS,PRPS2,CTPS1,ARFGAP1,ALDOC,AAMP,PPA1,MYO1E,SPG20,DPH1,PSME1,UBA1,GLMN,MDP1,AHCY,CUL4B,STEAP3,MAPRE1,IPO5,EEF2,ISYNA1,FGFR1,GSPT1,PDIA3,UCKL1,RPAP3,NAP1L4,KLC4,PRKAA2,SLC2A3,VTA1,TUBA4A,TWF1,PPP2R4,PYCRL,HSPH1,AMPD2,NUTF2,HSPA4,SDSL,GTPBP2,KIF5B,SGTA,NIF3L1,ATG3,NCK1,DSTN,SPRY2,TXNDC17,LSM14A,NCOA6,CLN3,NRBP1,OTUD5,GSK3A,PTGES3,EIF2B2,DYNC1H1,ISG15,NPEPPS,FYN,PSMD11,STAT6,MARS,IPO7,MAP2K1,ENO1,PRKAA1,UBE2M,ALDOA,DOCK7,CCT5,HSP90AA1,TRIP13,POLR3B,CAD,MVK,HNRNPM,ARRB2,PUS7,MYH10,RRM2,DNM2,EIF2B5,HSPBP1,NUDT2,CCT8,ABCE1,DNM1L,NUP62,PIK3R1,USP9X,DIAPH1,BIN1,PYGB,STIP1,PPME1,MAF1,CHTF18,KDM6A,ATF2,ACTR1B,UBQLN2,ARPC4,FNTB,ARAF,EIF4A1,PPP2R5D,TNIK,PCBP1,DARS,CAST,ACTB,ACACA,PPID,YWHAZ,EGFR,HLA-B,PLAA,LPIN3,COPS2,CALR,CBR1,CAND1,PRDX2,NOTCH2,MOCS2,HINT1,EIF4A2,LDHA,ACTR1A,ADK,COPS7A,MIF,HMGCS1,ARPC3,TXN,HSP90AB1,TSC2,CCDC6,UBR4,CEP170,ARMT1,CDA,OLA1,UBA7,VAC14,XPO7,IKBKAP,VASP,PRKCZ,SPINT2,LSM1,CCT7,SNX3,PKM,SNX12,MSN,VCL,AKR1B1,MMS19,YWHAQ,CASP7,PTK2,LXN,NFKBIB,ATXN3,NT5C2,ABCF3,PPIA,PPP2CB,KRI1,COPB1,GCLC,DVL2,TRMT112,ABCC3,WDR92,NFKB1,ARHGDIA,HECW2,TP53RK,NME7,CCT4,YWHAG,EIF6,PSMD7,ABCG1,FRYL,NSFL1C,CCT3,NAGK,CASP3,KPNB1,PSMA2,DSN1,KIF23,TALDO1,DDAH2,CTPS2,CLK1,EIF2S2,MAP3K3,HSPA1B,PAAF1,MAPKAPK3,MAPK1,PPIL1,ATG5,COPS8,CARHSP1,TRAF3IP1,GPN1,ASNA1,PPT1,ATP6V1D,UBQLN1,DDX39A,TCP1,MYL1,DCTD,STMN1,CSNK1D,RC3H1,MST1R,RP2,NOTCH3,PAFAH1B2,TKT,MAP4K4,NOM1,KPNA3,HDAC6,ILK,DNAJC7,UBE2V2,APEX1,FBXO6,MTMR6,ARFGEF2,CAMKK2,PPP6C,COPA,EPS15,TNPO2,USP4,CSE1L,IMPDH1,DNAJC21,SEPT9,NFIC,TUBA1A,BTF3L4,BCAR3,SNX1,CDC37,TWF2,PSMB2,PSMD6,MYH9,PPAN,IKBKG,UMPS,ISCU,FARSA,COPS5,GSPT2,CHCHD2,UBE3C,NELFE,PLEKHB2,RAD23B,ARF4,TUBB6,VCP,ARRB1,FOXO1,TUBB,LPIN1,LSM3,PFN1,CLCN7,ZNF622,PSMA7,HDAC4,DCUN1D1,LAMP2,MAT2A,EIF3B,CAP2,RPAP2,ARPC5,KRT18,COPS4,GPI,MOB1B,PTPRK,XPO1,MEPCE,ETF1,RTN4,NUDCD3,MCM2,TARDBP,FAM122A,PSMC3,EIF5B,DNM1,SAR1A,TUBGCP3,CAP1,URI1,CHMP2A,BAG6,PPP2R5B,TCEA1,CLUH,RELA,PPP3CB,EXOC6,SDCCAG3,WIPF1,INPPL1,FAM96A,FTSJ1,PRMT5,PRUNE,AKT1,RPS14,ARPC2,CASP8,SPG21,EIF2S3,PSMB3,XPO5" -1.198415979 -0.23265949 436 1883 NUCLEOTIDE SUGAR METABOLISM NUCLEOTIDE SUGAR METABOLISM 0.005440505 0.007974439 -1 "GFPT1,PGK1,GAPDH,NCK1,PIK3R1,HLA-B,PRDX2,TALDO1,MAT2A,AKT1,UXS1" -1.730950637 -0.565184964 11 24 3-OXO-10R-OCTADECATRIENOATE BETA-OXIDATION 3-OXO-10R-OCTADECATRIENOATE BETA-OXIDATION 0.005601494 0.007991464 -1 "MAP1LC3A,SQSTM1,GFPT1,APP,LAMP1,GALT,ENO2,ATP6V1B2,HUWE1,UBE2V1,GDI1,GAPDH,IFRD2,NEDD4L,GSTO1,CDK6,HSPA6,ABHD14B,UBA1,TIMP2,ARMC6,AHCY,EEF2,ISYNA1,PRKAA2,VTA1,HSPH1,PARK7,HSPA4,GDI2,GTPBP2,MRPS17,PTGES3,DYRK1A,ENO1,ALDOA,CCT8,STIP1,ATF2,HGS,TNIK,AK1,PPID,YWHAZ,EGFR,HLA-B,CALR,STAT1,CDK5,HINT1,HSP90AB1,RNASEH2A,MSN,VCL,YWHAQ,PPP2CB,CLDN12,DDX3X,KPNB1,CLK1,HSPA1B,MAPK1,ATG5" -1.37014107 -0.296042024 63 291 GLYOXYLATE AND DICARBOXYLATE METABOLISM GLYOXYLATE AND DICARBOXYLATE METABOLISM 0.005569895 0.007991464 -1 "APP,ENO2,CALCOCO2,ASNS,IDH1,PGD,PGK1,HUWE1,NDUFA4,ATP6V1E1,TUBB4B,GAPDH,PRDX1,FKBP1A,LDHB,AHSA1,GSTO1,PGM1,BAG3,ALDOC,CUL4B,ISYNA1,TUBA4A,PTGES3,ISG15,ENO1,ALDOA,HSP90AA1,TRIP13,PYGB,ATF2,EIF4A1,ACTB,ACAT2,YWHAZ,EGFR,WDR1,CALR,PRDX2,NOTCH2,EIF4A2,LDHA,HSP90AB1,CKB,PKM,YWHAQ,COPB1,ARHGDIA,HECW2,CCT4,CCT3,BMPR1A,HSPA1B,MAPK1,GLO1,UBQLN1,NOTCH3,TKT,ILK,NDUFB8,TUBA1A,SNX9,COPS5,MAP2K3,RAD23B,VCP,ARRB1" -1.390413907 -0.303819699 67 256 DIMETHYL-BRANCHED-CHAIN FATTY ACID MITOCHONDRIAL BETA-OXIDATION DIMETHYL-BRANCHED-CHAIN FATTY ACID MITOCHONDRIAL BETA-OXIDATION 0.006227003 0.008766964 -1 "MAP1LC3A,SQSTM1,APP,LAMP1,ENO2,HUWE1,GDI1,IFRD2,GSTO1,ABHD14B,UBA1,TIMP2,ARMC6,ISYNA1,PRKAA2,HSPH1,PARK7,HSPA4,GDI2,GTPBP2,PTGES3,ENO1,ALDOA,STIP1,ATF2,TNIK,YWHAZ,EGFR,HLA-B,CALR,STAT1,HINT1,HSP90AB1,MSN,VCL,YWHAQ,CLDN12,KPNB1,CLK1,MAPK1,ATG5,TKT,FBXO6,FERMT2,UBA5" -1.427350635 -0.323172208 45 187 N-GLYCAN BIOSYNTHESIS N-GLYCAN BIOSYNTHESIS 0.01420765 0.019743098 -1 "GFPT1,APP,PDIA4,LGALS3BP,HYOU1,ASS1,HSPA5,DAAM1,ENO2,ATP6V1A,ATP6V1B2,PRKAG2,PRKAR1A,TSG101,PAICS,PGK1,HUWE1,PDIA6,TUBB3,PRKAR1B,TUBB4B,IPO4,GAPDH,ANTXR1,IFRD2,NEDD4L,PDXDC1,GMPPB,HSPA6,BAG3,NAE1,EIF4EBP1,CTPS1,ARFGAP1,DYNC1I2,SRM,DCTN2,TIMP2,CUL4B,PDIA3,FUT11,PAFAH1B1,TUBA4A,HSP90B1,HSPH1,HSPA4,CLN3,DYNC1H1,ISG15,PAPSS1,ENO1,ALDOA,QSOX1,HSP90AA1,DCTN1,RRM2,DNM2,CCT8,ZNFX1,CFP,ATF2,ARAF,ACTB,ACACA,AK1,EGFR,HLA-B,CALR,CAND1,AGRN,PRDX2,SLC38A1,SUSD2,HSP90AB1,BABAM1,VAC14,IKBKAP,SORT1,SPINT2,CCT7,MMS19,VBP1,REPS2,DCTN3,NFKB1,CCT4,EIF6,PPAT,DYNC1LI2,KPNB1,CTPS2,LRSAM1,STUB1,TNFRSF10D,HSPA1B,COMMD3,CSNK1D,HDAC6,ILK,FBXO6,COPA,UGGT1,UBA5,GIPC1,TUBA1A,STX3,PFDN4,DCTN5,COPS5,TUBB6,NGLY1,TUBB,DCUN1D1,GPI,PTPRK,XPO1,MCM2,GIT1,PSMC3" -1.265766065 -0.259706009 119 538 LYSINE METABOLISM LYSINE METABOLISM 0.016005054 0.021955651 -1 "RPTOR,SDCBP,SARS,MAP1LC3A,CENPE,SQSTM1,AARS,HSPB1,GFPT1,TBC1D15,APP,GARS,XPOT,CTH,PDIA4,LOXL2,TARS,LGALS3BP,GYS1,HYOU1,PDCD6IP,ASS1,PRRC2C,CRELD2,YARS,GALT,HSPA5,ATIC,OGT,TNFRSF21,ENO2,GALE,TOM1,GOT1,SNX8,CALCOCO2,ATP6V1A,CNDP2,ATP6V1B2,MTHFD1,COPRS,RPS6KA3,IDH1,NARS,PRKAR1A,ATP6V1C1,PTPRS,PGD,PFKM,HUWE1,TPI1,PDIA6,UBE2V1,TUBB3,PRKAR1B,GDI1,PCYT2,IMPDH2,PPP1R7,NDRG1,ATP6V1E1,TUBB4B,SMS,PSMD9,IPO4,GAPDH,PRDX1,KLC1,PFKL,CRELD1,WDR77,FKBP1A,LARS,NEDD4L,IRGQ,TGM2,MDH1,GART,NAP1L1,BLMH,ACSS2,BCAT1,SEC31A,GSTO1,AKR1A1,GMPPB,SCRIB,CDK6,PFKP,HSPA6,ADSS,PGM1,MAP2K2,RNF19B,UGP2,TAX1BP1,ADSL,SHMT1,IARS,FASN,CTPS1,ALDOC,PPA1,SRM,MYO1E,PSME1,UBA1,PAFAH1B3,AHCY,CUL4B,ACO1,STEAP3,IPO5,EEF2,ISYNA1,EPRS,PDIA3,ELP4,NAP1L4,KLC4,PLEC,PRKAA2,TUBA4A,PYCRL,HSP90B1,HSPH1,PARK7,NUTF2,HSPA4,SDSL,NTN4,GDI2,GTPBP2,BAX,KIF5B,SGTA,TSR1,NCK1,DSTN,TOLLIP,GSTCD,IREB2,NCOA6,CLN3,EIF2B2,SH3GL1,PSME2,ISG15,NPEPPS,FYN,PSMD11,MARS,PAPSS1,DYRK1A,ENO1,UBE2M,ALDOA,RBM14,PRKCI,CCT5,HSP90AA1,TRIP13,POLR3B,CAD,HNRNPM,ARRB2,FBP1,VAT1,MYH10,WWP2,RRM2,DNM2,EIF2B5,CCT8,ABCE1,DNM1L,PIK3R1,BIN1,ZNFX1,PYGB,STIP1,LIN9,PACSIN1,POTEE,KDM6A,ATF2,STK10,EIF4A1,HECTD1,HGS,TRERF1,TNIK,PCBP1,DARS,ASPSCR1,ACTB,ACACA,ACAT2,AK1,PPID,YWHAZ,EGFR,HLA-B,PLAA,FHIT,ERP44,CRK,COPS2,CALR,CAND1,PRDX2,STAT1,CDK5,HEBP2,EIF4A2,ADK,PPP1R12A,MLLT4,PSMB7,HMGCS1,TXN,HSP90AB1,PFDN1,S100A4,TSC2,UBR4,CEP170,PHGDH,SSFA2,BABAM1,KLC2,EIF4B,OLA1,PSMB6,PIN4,TXNDC9,TRIM37,BOD1,IPO13,COMMD1,RNASEH2A,LSM1,CCT7,SNX3,MTM1,PKM,VCL,MMS19,YWHAQ,KANK1,ATXN3,CKS1B,ABCF3,PPIA,PPP2CB,AKR1D1,ZFP36,KRI1,COPB1,GCLC,NTPCR,HECW2,MAP1B,TP53RK,FAT1,CCT4,YWHAG,EIF6,PSMD7,SLC35F6,SERPINB9,SHC1,NSFL1C,CCT3,FRMD6,DDX3X,KPNB1,PSMA2,TALDO1,CTPS2,IFNGR1,EIF2S2,MCL1,ZAK,STUB1,PLS3,TNFRSF10D,MAP3K3,HSPA1B,PAAF1,MAPKAPK3,MAPK1,CAPZA2,ATG5,DRG2,GPN1,ASNA1,PPT1,ATP6V1D,UBQLN1,THADA,IL18,HELZ,TCP1,MYL1,S100A11,TIMP3,AJUBA,FLII,CSNK1D,PAFAH1B2,TKT,NOM1,HDAC6,ILK,UBE2V2,MYL12A,FBXO6,SETD1B,PSMB1,PPP6C,COPA,EPS15,TNPO2,PLS1,USP4,CSE1L,IMPDH1,UBA5,DNAJC21,SEPT9,FUNDC2,TUBA1A,BTF3L4,SH3RF1,PLCG1,CBX3,IGFBP3,LOXL4,CDC37,TTC39C,CABLES2,PSMB2,PSMD6,MYH9,PPAN,IKBKG,UMPS,FBXO7,FNBP1,FARSA,COPS5,ATE1,ESCO2,TTC1,UBE3C,RAD23B,ARF4,TUBB6,SMYD3,VCP,ARRB1,MPI,PSMD5,PINK1,FOXO1,LRRC40,TUBB,RRP8,PSMA7,HDAC4,DCUN1D1,MAT2A,CARM1,ATAD3A,TRAF2,CAP2,CIRBP,RAPGEF6,MALT1,GPI,MOB1B,BCL9L,XPO1,EXOC2,ITPR3,TJP2,NUDCD3,MCM2,TARDBP,PSMC3,EIF5B,SAR1A,SSH3,PDCL3,TUBGCP3,CAP1,BAG6,CLUH,RELA,IDE,PPP3CB,MAP3K7,CRBN,PRMT5,PRUNE,AKT1,RPS14,ARPC2,PARG,EIF2S3,ATP5J2,PSMB3,TANK,KIAA1217,TUBB4A,CAPZB,UBE2E2,NT5C3B,BUB1,SNRPN,PXN,UBE2D2,SEC23B,VHL,PRDX5" -1.166170636 -0.226841129 426 1753 HEPARAN SULFATE DEGRADATION HEPARAN SULFATE DEGRADATION 0.016773407 0.022718411 -1 "LOXL2,HYOU1,NDST1,HSPA5,PDIA6,IDUA,HARS,FGFR1,PRKAA2,NCK1,PTPN11,FYN,PRKAA1,ABCE1,PIK3R1,DNAJC3,MSN,SHC1,MAPK1,FBXO6,UGGT1,PLCG1" -1.4534729 -0.36347419 22 89 PROTEOGLYCAN BIOSYNTHESIS PROTEOGLYCAN BIOSYNTHESIS 0.021638331 0.028941267 1 "SDF4,CHST14,POLR2A,ST3GAL4,HNRNPD,PLAUR,ELAVL1,SDC4,INO80,NAAA,FAM134C,CHST12,GOLIM4,ERGIC3,RABL6,PHF5A,CHST15,PLEKHA5,SEC62,EXTL3,PON2,ERBB2,GPC6,CSPG4,LEMD3,TIMELESS,KDM5B,FARS2,CHPF2,TMEM214,TMUB1,GLCE,NRG1,PBXIP1,CBX8,PPP3CA,CPSF3L,B3GAT3,CKAP4,HLA-DPA1,TMX4,GOLT1B" 1.358645102 0.299262996 42 128 HYALURONAN METABOLISM HYALURONAN METABOLISM 0.036789842 0.048598927 -1 "EIF4EBP1,FGFR1,TUBA4A,PTPN11,FYN,ABCE1,PIK3R1,CRK,TSNAX,EIF6,SHC1,MAPK1,FBXO6,TUBA1A,PLCG1,MCM2,BAG6,VHL,FLRT2,EIF4EBP2,PIK3R2,FRS2,NAPRT,CDK4,CBL,PPP5C" -1.431023558 -0.390393945 26 54 VITAMIN B3 (NICOTINATE AND NICOTINAMIDE) METABOLISM VITAMIN B3 (NICOTINATE AND NICOTINAMIDE) METABOLISM 0.037695779 0.049188395 -1 "RPTOR,PGRMC2,SDCBP,MAP1LC3A,CENPE,PNP,APP,PRRC2C,ATP6V1B2,NDUFA4,NAMPT,VPS4B,NEDD4L,BLMH,HSPA6,MAP2K2,BAG3,PSEN2,GLMN,STEAP3,NADSYN1,ISYNA1,HSPH1,HSPA4,ENO1,ALDOA,HSP90AA1,TRIP13,CAD,HSPBP1,ABCE1,ATF2,PPP2R5D,PATL1,ACTB,PPID,YWHAZ,EGFR,HLA-B,PLAA,HSP90AB1,CEP170,ARMT1,XPO7,YWHAQ,NT5C2,ABCC3,HECW2,NME7,CCT4,YWHAG,AIP,KPNB1,STUB1,HSPA1B,MAPK1,UBQLN1,CSNK1D,TNPO2,SCAMP2,PFDN4,TRAF3IP2,SIRT2,TRAF2,MOB1B,XPO1,RTN4,TJP2,MCM2,ABCF1,PPP2R5B,TCEA1" -1.253190681 -0.269447573 72 306 VITAMIN B2 (RIBOFLAVIN) METABOLISM VITAMIN B2 (RIBOFLAVIN) METABOLISM 0.04852449 0.062555668 -1 "SDCBP,HSPA5,ATP6V1B2,VPS4B,TRADD,HSPA6,ISYNA1,PDCD5,EIF2B2,ALDOA,CAD,RSU1,EGFR,HMGCS1,HSP90AB1,ARMT1,PPP2CB,SLC35F6,STX12,HSPA1B,MAPK1,ILK,FBXO6" -1.341931371 -0.333518941 23 93 PARATHIO DEGRADATION PARATHIO DEGRADATION 0.051320755 0.064603774 -1 "PGRMC2,MAP1LC3A,SNX2,EIF2A,BLMH,HSPA6,PSME1,HSPA4,NAA15,NAA50,DBNL,PTPN11,HSP90AA1,PYGB,ATF2,YWHAZ,MLLT4,HSP90AB1,TPP2,SNX3,PKM,EIF2S2,PSMF1,CAB39,DTD1,ETF1,MCM2,IQGAP1,TCEA1,EXOC6,SBDS" -1.318101658 -0.3220286 31 106 UREA CYCLE/AMINO GROUP METABOLISM UREA CYCLE/AMINO GROUP METABOLISM 0.050988225 0.064603774 -1 "RPTOR,SDCBP,SARS,MAP1LC3A,CENPE,SQSTM1,AARS,HSPB1,GFPT1,TBC1D15,APP,GARS,XPOT,CTH,LAMP1,PDIA4,LOXL2,TARS,LGALS3BP,GYS1,HYOU1,PDCD6IP,ASS1,CRELD2,GALT,HSPA5,ATIC,OGT,TNFRSF21,ENO2,GALE,WARS,GOT1,CALCOCO2,ATP6V1A,CNDP2,ATP6V1B2,MTHFD1,RPS6KA3,IDH1,NARS,PRKAR1A,ATP6V1C1,PTPRS,PGD,PFKM,PGK1,HUWE1,TPI1,ATOX1,UBE2V1,TUBB3,PRKAR1B,GDI1,PCYT2,IMPDH2,PPP1R7,CAMSAP2,ATP6V1E1,TUBB4B,SMS,IPO4,GAPDH,PRDX1,PFDN2,KLC1,PFKL,CRELD1,WDR77,FKBP1A,VPS4B,LARS,NUDT5,NEDD4L,IRGQ,GART,NAP1L1,BLMH,ACSS2,LDHB,BCAT1,SEC31A,PPP1R13L,APRT,GSTO1,AKR1A1,IMPA1,GMPPB,CDK6,PFKP,HSPA6,ADSS,PGM1,MAP2K2,AHNAK2,RNF19B,BAG3,UGP2,SHMT1,IARS,FASN,CTPS1,PPA1,SRM,MYO1E,PSME1,UBA1,TIMP2,ARMC6,TGFBR2,PAFAH1B3,AHCY,CUL4B,STEAP3,MAPRE1,IPO5,EEF2,ISYNA1,EPRS,PDIA3,NAP1L4,KLC4,PLEC,PRKAA2,SLC2A3,MTRR,TUBA4A,PYCRL,HSP90B1,HSPH1,PARK7,NUTF2,HSPA4,SDSL,GDI2,GTPBP2,ABTB2,KIF5B,SGTA,NAA15,TSR1,NCK1,DSTN,TOLLIP,GSTCD,RIN1,IREB2,NCOA6,PTGES3,EIF2B2,ISG15,NPEPPS,FYN,PSMD11,STAT6,MARS,IPO7,MAP2K1,PAPSS1,ENO1,ALDOA,RBM14,PRKCI,CCT5,HSP90AA1,TRIP13,POLR3B,CAD,HNRNPM,PUS7,FBP1,MYH10,WWP2,RRM2,DERA,EIF2B5,CCT8,ABCE1,DNM1L,PIK3R1,CMBL,PYGB,STIP1,PACSIN1,POTEE,CHTF18,KDM6A,ATF2,UBQLN2,ARPC4,ARAF,EIF4A1,HECTD1,TNIK,PCBP1,DARS,ASPSCR1,CAST,ACTB,ACACA,ACAT2,AK1,PPID,YWHAZ,EGFR,HLA-B,PLAA,FHIT,ERP44,CRK,COPS2,SMG6,CAND1,PRDX2,NOTCH2,MOCS2,STAT1,TSNAX,EIF4A2,LDHA,ADK,PPP1R12A,MLLT4,HMGCS1,ARPC3,TXN,HSP90AB1,PFDN1,S100A4,TSC2,CCDC6,CEP170,PHGDH,CKB,BABAM1,KLC2,OLA1,PSMB6,UBA7,PIN4,TXNDC9,XPO7,TRIM37,BOD1,IPO13,FNTA,SORT1,SPINT2,LSM1,CCT7,SNX3,MTM1,PKM,AKR1B1,MMS19,YWHAQ,CKS1B,PPIA,PPP2CB,AKR1D1,KRI1,COPB1,GCLC,DVL2,DCTN3,NFKB1,HECW2,MAP1B,TP53RK,FAT1,CCT4,YWHAG,ALDH16A1,EIF6,PSMD7,SLC35F6,SERPINB9,FRYL,SHC1,NSFL1C,CCT3,DYNC1LI2,FRMD6,DDX3X,KPNB1,TALDO1,CTPS2,CLK1,EIF2S2,ZAK,STUB1,PLS3,HSPA1B,PAAF1,MAPKAPK3,MAPK1,CAPZA2,ATG5,DRG2,TRAF3IP1,GPN1,ATP6V1D,UBQLN1,THADA,HELZ,TCP1,MYL1,TIMP3,AJUBA,FLII,CSNK1D,RC3H1,NOTCH3,TKT,NOM1,HDAC6,ILK,UBE2V2,APEX1,MYL12A,SH3KBP1,FBXO6,ABI1,SETD1B,PPP6C,COPA,UGGT1,TNPO2,PLS1,USP4,CSE1L,IMPDH1,UBA5,DNAJC21,SEPT9,TUBA1A,BTF3L4,PLCG1,CBX3,IGFBP3,LOXL4,CDC37,CABLES2,PSMB2,PSMD6,MYH9,PPAN,LATS1,FARSA,COPS5,ATE1,ESCO2,TTC1,UBE3C,RAD23B,ARF4,TUBB6,SMYD3,VCP,MPI,FOXO1,LRRC40,TUBB,RRP8,HDAC4,DCUN1D1,LAMP2,MAT2A,CARM1,EIF3B,ATAD3A,ARPC5,RMND5A,MALT1,GPI,MOB1B,KLC3,BCL9L" -1.126369106 -0.219015487 378 1783 1- AND 2-METHYLNAPHTHALENE DEGRADATION 1- AND 2-METHYLNAPHTHALENE DEGRADATION 0.150329003 0.187037248 -1 "APP,TNIP1,PRDX1,HSPA6,HSPH1,HSPA4,CCT8,CAND1" -1.242800698 -0.359226784 8 41 CARNITINE SHUTTLE CARNITINE SHUTTLE 0.180593817 0.222109637 -1 "HSPA5,ATP6V1B2,HUWE1,NDUFA4,ACSS2,HSPA6,RIC8A,HSPH1,HSPA4,CLN3,EIF2B2,ENO1,CLIC1,ALDOA,HSP90AA1,HSP90AB1,MCL1,HSPA1B,MAPK1,HDAC6,FBXO6" -1.175427403 -0.295380249 21 86 SIALIC ACID METABOLISM SIALIC ACID METABOLISM 0.190442923 0.231561281 -1 "SDCBP,APP,ENO2,ATP6V1A,GDI1,PGLS,SERINC5,IMPA1,HSPA6,PGM1,BAG3,EIF4EBP1,KEAP1,CTPS1,ARFGAP1,TUBA4A,HSPH1,HSPA4,GDI2,FYN,HSP90AA1,POLR3B,ABCE1,EGFR,SERINC1,CRK,TSNAX,TXN,HSP90AB1,IPO13,MMS19,OSBPL11,CTPS2,HSPA1B,CAPZA2,SERINC3,NOTCH3,ILK,NDUFAF7,FBXO6,EPS15,CSE1L,SCAMP2,TUBA1A,HERPUD1,VCP,KRT18,MEPCE,MCM2,BAG6,CLUH" -1.128040957 -0.252528018 51 205 GLYCOSPHINGOLIPID BIOSYNTHESIS - GANGLIOSERIES GLYCOSPHINGOLIPID BIOSYNTHESIS - GANGLIOSERIES 0.221980751 0.266875735 1 "SDF4,NEU1,PLK1,CHST14,VIM,H2AFX,ATP6AP2,CTSA,NCOA5,MBD2,HNRNPD,ELAVL1,GLB1,SDC4,NAAA,CHST12,RABL6,PHF5A,CHST15,SMC6,TFIP11,PON2,GPC6,TMEM259,CSPG4,ZMYM2,INTS1,KDM5B,FARS2,ST3GAL1" 1.101683212 0.240173969 30 135 GLYCOSPHINGOLIPID METABOLISM GLYCOSPHINGOLIPID METABOLISM 0.228996945 0.272251924 -1 "SDCBP,SQSTM1,GFPT1,APP,HYOU1,NDST1,ATP6V1G1,ACY1,ATP6V1A,ATP6V1B2,RPS6KA3,TUBB3,TUBB4B,IPO4,PFDN2,LDHB,UGCG,GMPPB,SCRIB,CDK6,HSPA6,HARS,KEAP1,TNFRSF10B,ARMC6,TMEM51,EEF2,TSPAN3,TUBA4A,HSP90B1,HSPH1,HSPA4,SCAMP3,FYN,CCT5,HSP90AA1,TRIP13,CAD,CCT8,ABCE1,DNM1L,MTHFR,UBQLN2,FNTB,YWHAZ,EGFR,PLAA,CDK5,LDHA,NUDCD1,HSP90AB1,PLEKHM1,IPO13,PRKCZ,SPINT2,CCT7,ILKAP,YWHAQ,CASP7,HECW2,CCT4,WWTR1,CCT3,KPNB1,BMPR1A,HSPA1B,OTUD6B,UBQLN1,DDX39A,TCP1,CSNK1D,RC3H1,NOTCH3,FBXO6,COPA,TNPO2,TUBA1A,CHST11,PFDN4,TCEAL4,RAD23B,TUBB6,VCP,TUBB,CYLD,SIRT2,MAT2A,TRAF2,PTPRK,XPO1,MEPCE,MCM2,KDELR3,MRM1,BMPR2,BAG6,CLUH" -1.085083186 -0.227556995 97 414 VITAMIN B12 (CYANOCOBALAMIN) METABOLISM VITAMIN B12 (CYANOCOBALAMIN) METABOLISM 0.267044168 0.313996988 1 "MOV10,ELAVL1,NXF1,ICT1,B9D2,MMADHC,MRRF,B9D1,XRCC3" 1.151144266 0.389496335 9 17 KERATAN SULFATE BIOSYNTHESIS KERATAN SULFATE BIOSYNTHESIS 0.279442877 0.325004216 -1 "ENO2,GOLM1,CUL4B,TUBA4A,CAPN2,SCAMP2,LDLR" -1.134201155 -0.367533467 7 25 CAFFEINE METABOLISM CAFFEINE METABOLISM 0.343678161 0.393834446 1 "ICAM1,CDH1,ERBB2,IGF1R,NAT10,NAT14,NBN" 1.070122293 0.347136921 7 20 GLYCOSAMINOGLYCAN DEGRADATION GLYCOSAMINOGLYCAN DEGRADATION 0.345985401 0.393834446 -1 "LOXL2,HYOU1,NDST1,HSPA5,PDIA6,IDUA,EIF4EBP1,HARS,FGFR1,PRKAA2,TUBA4A,COL2A1,NCK1,PTPN11,FYN,PRKAA1,ABCE1,PIK3R1,CRK,TSNAX,DNAJC3,MSN,SHC1,MAPK1,PLXNA2,FBXO6,UGGT1,TUBA1A,PLCG1,VCP,DCUN1D1,PTPRK,MEPCE,FBXO21,BAG6" -1.048350678 -0.245133013 35 143 HEPARAN SULFATE BIOSYNTHESIS HEPARAN SULFATE BIOSYNTHESIS 0.380039419 0.428044399 -1 "EXT1,FYN,PIK3R1,CRK,PLCG1" -1.059367271 -0.383596199 5 16 DYNORPHIN METABOLISM DYNORPHIN METABOLISM 0.420038201 0.468167578 -1 "APP,KLC4,THOP1,EGFR,HSP90AB1,MPP6,TRAF2" -1.02011146 -0.323974429 7 27 GLYCOSPHINGOLIPID BIOSYNTHESIS - LACTOSERIES GLYCOSPHINGOLIPID BIOSYNTHESIS - LACTOSERIES 0.430496454 0.474877532 -1 "CLN3,GNPTAB,IPO13,HECW2,APOB,SCAMP2" -1.015849322 -0.35223337 6 19 CHONDROITIN SULFATE DEGRADATION CHONDROITIN SULFATE DEGRADATION 0.459126199 0.50129085 -1 "LOXL2,NDST1,HSPA5,IDUA,EIF4EBP1,FGFR1,TUBA4A,PTPN11,FYN,ABCE1,PIK3R1,CRK,TSNAX,SHC1,MAPK1,FBXO6,TUBA1A,PLCG1,PTPRK,FBXO21,BAG6,FLRT2,EIF4EBP2,PIK3R2,FRS2,AP3M1,MTHFSD,NAPRT,CDK4,ARSA,CBL,PPP5C,XYLT2,MYC" -0.999175978 -0.249279196 34 91 O-GLYCAN BIOSYNTHESIS O-GLYCAN BIOSYNTHESIS 0.508477142 0.549566204 -1 "APP,ENO2,CTSL,IPO9,DYNC1I2,DCTN2,VPS36,PAFAH1B1,DYNC1H1,PAPSS1,ALDOA,DCTN1,RSU1,CCT7,DCTN3,DYNC1LI2,BMPR1A,STUB1,PARVA,BTF3L4,DCTN5,COPS5,LAP3,PTPRK" -0.977507043 -0.240458266 24 100 N-GLYCAN DEGRADATION N-GLYCAN DEGRADATION 0.590928914 0.632293938 -1 "APP,GYS1,ENO2,ATP6V1A,MARK2,ATP6V1E1,HSPA6,EIF4EBP1,KEAP1,AHCY,TUBA4A,HSPH1,HSPA4,FYN,HSP90AA1,POLR3B,ABCE1,EGFR,CRK,TSNAX,HSP90AB1,DNAJC3,VCL,PPIA,HSPA1B,CSNK1D,NOTCH3,FBXO6,TUBA1A,VCP,TMEM55A,PTPRK,MEPCE,MCM2,BAG6" -0.945138611 -0.219127389 35 154 FATTY ACID OXIDATION FATTY ACID OXIDATION 0.637730446 0.675615423 -1 "HSPA6,PUS7,CCT3,HSPA1B" -0.872667173 -0.311534694 4 17 VITAMIN D3 (CHOLECALCIFEROL) METABOLISM VITAMIN D3 (CHOLECALCIFEROL) METABOLISM 0.68080294 0.714175633 1 "CYP1B1,POLR2A,CYP2S1,GLRX5,ELAVL1,HIST1H4A,HDAC1,CYB5A,ADCK4,CYP27A1,POLDIP2,PDSS2,CYP51A1,DDX41,ARSE,D2HGDH,PTPMT1,HDAC2,PITRM1,C1QBP,BCKDHA,POR,ECH1,HSPD1,COQ5" 0.901397769 0.213960935 25 79 GLYCOSPHINGOLIPID BIOSYNTHESIS - NEOLACTOSERIES GLYCOSPHINGOLIPID BIOSYNTHESIS - NEOLACTOSERIES 0.765257416 0.79497615 -1 "GOLM1,CUL4B,TUBA4A,CAPN2,IPO13,HECW2" -0.812921275 -0.245923892 6 33 KERATAN SULFATE DEGRADATION KERATAN SULFATE DEGRADATION 0.805288817 0.828518302 -1 "APP,GYS1,MARK2,CDK6,EIF4EBP1,KEAP1,PRKAA2,TUBA4A,NCK1,FYN,PRKAA1,ABCE1,EGFR,CRK,CDK5,TSNAX,MSN,VCL,NOTCH3,FBXO6,TUBA1A,VCP,SIRT2,PTPRK,MEPCE,MCM2,BAG6" -0.850638371 -0.202844913 27 124 GLYCOSPHINGOLIPID BIOSYNTHESIS - GLOBOSERIES GLYCOSPHINGOLIPID BIOSYNTHESIS - GLOBOSERIES 0.837521461 0.853474251 -1 "APP,ENO2,CDK6,EIF4EBP1,TUBA4A,FYN,ABCE1,CRK,CDK5,TSNAX,RC3H1,FBXO6,TUBA1A,SIRT2,BAG6,CSGALNACT2,EIF4EBP2" -0.807724851 -0.208636762 17 73 ELECTRON TRANSPORT CHAIN ELECTRON TRANSPORT CHAIN 0.878492621 0.886780287 -1 "CENPE,ATP6V1B2,TUBB3,NDUFA4,TUBB4B,NAP1L1,HSPA6,NAP1L4,HSPH1,HSPA4,ALDOA,PUS7,ACTB,MT-ND5,CCT7,YWHAG,CCT3,MCL1,HSPA1B,RAPGEF2,NDUFAF7,NDUFB8,TTC1,CHCHD2,TUBB6,TUBB,NDUFB1,PPP3CB,TUBB4A,MT-ND4,VHL" -0.833739997 -0.189794084 31 181 BLOOD GROUP BIOSYNTHESIS BLOOD GROUP BIOSYNTHESIS 0.91492891 0.91492891 1 "LRP5,TMEM259,GCNT2,ZMYM2,INTS1,METTL9,FAM3C,RPL8" 0.708991292 0.210661642 8 28