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no-margin-bottom"> <div class="pane-content"> <div class="highwire-article-citation highwire-citation-type-highwire-article node40618" data-apath="/kidney360/early/2021/06/30/KID.0003772021.atom" data-hw-author-tooltip-instance="highwire_author_tooltip" data-node-nid="40618" data-pisa="kidney360;KID.0003772021v1" data-pisa-master="kidney360;KID.0003772021" id="node40618--21704528371"> <div class="highwire-cite highwire-cite-highwire-article highwire-citation-jnl-asnjnls-styles-article-title-complete clearfix has-author-tooltip highwire-citation-highwire-article-top-a"> <div class="highwire-cite-overline"> <span class="highwire-cite-metadata-art-cat highwire-cite-metadata">Original Investigation</span> </div> <h1 class="highwire-cite-title" id="page-title">Peroxisomal L-bifunctional protein (EHHADH) deficiency causes male-specific kidney hypertrophy and proximal tubular injury in mice</h1> <div class="highwire-cite-authors"> <span class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">Pablo Ranea-Robles</span>, <span class="highwire-citation-author" data-delta="1">Kensey Portman</span>, <span class="highwire-citation-author" data-delta="2">Aaron Bender</span>, <span class="highwire-citation-author" data-delta="3">Kyung Lee</span>, <span class="highwire-citation-author" data-delta="4">John Cijiang He</span>, <span class="highwire-citation-author" data-delta="5">David J. Mulholland</span>, <span class="highwire-citation-author" data-delta="6">Carmen Argmann</span> and <span class="highwire-citation-author" data-delta="7">Sander M. Houten</span></span> </div> <div class="highwire-cite-metadata"> <span class="highwire-cite-metadata-journal highwire-cite-metadata">Kidney360 </span> <span class="highwire-cite-metadata-date highwire-cite-metadata">June 2021, </span> <span class="highwire-cite-metadata-pages highwire-cite-metadata">10.34067/KID.0003772021; </span> <span class="highwire-cite-metadata-doi highwire-cite-metadata">DOI: https://doi.org/10.34067/KID.0003772021 </span> </div> </div> <div id="hw-article-author-popups-node40618--21704528371" style="display: none;"> <div class="author-tooltip-0"> <div class="author-tooltip-name">Pablo Ranea-Robles </div> <div class="author-tooltip-affiliation"> <span class="author-tooltip-text"> <div class="author-affiliation"><span class="nlm-sup">1</span>Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, United States</div> </span> </div> <ul class="author-tooltip-find-more"> <li class="author-tooltip-gs-link first">Find this author on Google Scholar</li> <li class="author-tooltip-pubmed-link">Find this author on PubMed</li> <li class="author-site-search-link">Search for this author on this site</li> <li class="author-orcid-link last">ORCID record for Pablo Ranea-Robles</li> </ul> </div> <div class="author-tooltip-1"> <div class="author-tooltip-name">Kensey Portman </div> <div class="author-tooltip-affiliation"> <span class="author-tooltip-text"> <div class="author-affiliation"><span class="nlm-sup">2</span>Icahn School of Medicine at Mount Sinai, United States</div> </span> </div> <ul class="author-tooltip-find-more"> <li class="author-tooltip-gs-link first">Find this author on Google Scholar</li> <li class="author-tooltip-pubmed-link">Find this author on PubMed</li> <li class="author-site-search-link last">Search for this author on this site</li> </ul> </div> <div class="author-tooltip-2"> <div class="author-tooltip-name">Aaron Bender </div> <div class="author-tooltip-affiliation"> <span class="author-tooltip-text"> <div class="author-affiliation"><span class="nlm-sup">2</span>Icahn School of Medicine at Mount Sinai, United States</div> </span> </div> <ul class="author-tooltip-find-more"> <li class="author-tooltip-gs-link first">Find this author on Google Scholar</li> <li class="author-tooltip-pubmed-link">Find this author on PubMed</li> <li class="author-site-search-link last">Search for this author on this site</li> </ul> </div> <div class="author-tooltip-3"> <div class="author-tooltip-name">Kyung Lee </div> <div class="author-tooltip-affiliation"> <span class="author-tooltip-text"> <div class="author-affiliation"><span class="nlm-sup">3</span>Medicine/Division of Nephrology, Icahn School of Medicine at Mount Sinai, United States</div> </span> </div> <ul class="author-tooltip-find-more"> <li class="author-tooltip-gs-link first">Find this author on Google Scholar</li> <li class="author-tooltip-pubmed-link">Find this author on PubMed</li> <li class="author-site-search-link">Search for this author on this site</li> <li class="author-orcid-link last">ORCID record for Kyung Lee</li> </ul> </div> <div class="author-tooltip-4"> <div class="author-tooltip-name">John Cijiang He </div> <div class="author-tooltip-affiliation"> <span class="author-tooltip-text"> <div class="author-affiliation"><span class="nlm-sup">4</span>Medicine/Nephrology, Mount Sinai School of Medicine, United States</div> </span> </div> <ul class="author-tooltip-find-more"> <li class="author-tooltip-gs-link first">Find this author on Google Scholar</li> <li class="author-tooltip-pubmed-link">Find this author on PubMed</li> <li class="author-site-search-link last">Search for this author on this site</li> </ul> </div> <div class="author-tooltip-5"> <div class="author-tooltip-name">David J. Mulholland </div> <div class="author-tooltip-affiliation"> <span class="author-tooltip-text"> <div class="author-affiliation"><span class="nlm-sup">5</span>Oncological Sciences, Icahn School of Medicine at Mount Sinai, United States</div> </span> </div> <ul class="author-tooltip-find-more"> <li class="author-tooltip-gs-link first">Find this author on Google Scholar</li> <li class="author-tooltip-pubmed-link">Find this author on PubMed</li> <li class="author-site-search-link last">Search for this author on this site</li> </ul> </div> <div class="author-tooltip-6"> <div class="author-tooltip-name">Carmen Argmann </div> <div class="author-tooltip-affiliation"> <span class="author-tooltip-text"> <div class="author-affiliation"><span class="nlm-sup">6</span>Genetics and Genomics Sciences, Icahn School of Medicine at Mount Sinai, United States</div> </span> </div> <ul class="author-tooltip-find-more"> <li class="author-tooltip-gs-link first">Find this author on Google Scholar</li> <li class="author-tooltip-pubmed-link">Find this author on PubMed</li> <li class="author-site-search-link last">Search for this author on this site</li> </ul> </div> <div class="author-tooltip-7"> <div class="author-tooltip-name">Sander M. Houten </div> <div class="author-tooltip-affiliation"> <span class="author-tooltip-text"> <div class="author-affiliation"><span class="nlm-sup">7</span>Genetics and Genomic Sciences, Icahn School of Medicine At Mount Sinai, United States</div> </span> </div> <ul class="author-tooltip-find-more"> <li class="author-tooltip-gs-link first">Find this author on Google Scholar</li> <li class="author-tooltip-pubmed-link">Find this author on PubMed</li> <li class="author-site-search-link">Search for this author on this site</li> <li class="author-orcid-link">ORCID record for Sander M. Houten</li> <li class="author-corresp-email-link last"> <span>For correspondence: sander.houten@mssm.edu</span> </li> </ul> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="panel-row-wrapper clearfix"> <div class="main-content-wrapper grid-17 suffix-1 alpha"> <div class="panel-panel panel-region-content"> <div class="inside"> <div class="panel-pane pane-highwire-markup border-top-hairline"> <div class="pane-content"> <div class="highwire-markup"> <div xmlns:xhtml="http://www.w3.org/1999/xhtml" class="content-block-markup"> <div> <span class="highwire-journal-article-marker-start"/> <div class="auto-clean"> <span style="font-family: Verdana,Arial,Helvetica,sans-serif; font-size: 83.33%"> <h2>Supplemental Data</h2> <ul> <li> <a class="rewritten" data-hide-link-title="0" data-icon-position="" href="/highwire/filestream/41122/field_highwire_adjunct_files/0/KID.0003772021SupplementaryData.pdf">Supplemental Data</a> </li> <li> <a class="rewritten" 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