Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS Tumor_Sample_Barcode Mutation_Status AAChange Transcript_Id TxChange Mutation_g GeneDetail.refGene Patient Stage VAF Genotype "MEF2B,MEF2BNB-MEF2B" hg19 chr19 19257953 19257953 + nonsynonymous_SNV SNV C C T . pt1_T1_B Somatic p.G145R NM_001145785 c.433G>A g.19257953C>T . pt1 T1 3 0/1 GRIN2A hg19 chr16 9857046 9857046 + nonsynonymous_SNV SNV C C T . pt1_T1_B Somatic p.R1452H NM_001134407 c.4355G>A g.9857046C>T . pt1 T1 16.99 0/1 KMT2D hg19 chr12 49425085 49425085 + nonsynonymous_SNV SNV C C T . pt1_T1_B Somatic p.R4468Q NM_003482 c.13403G>A g.49425085C>T . pt1 T1 19.62 0/1 ERG hg19 chr21 39795422 39795422 + nonsynonymous_SNV SNV C C T rs140580933 pt1_T1_B Somatic p.V100I NM_182918 c.298G>A g.39795422C>T . pt1 T1 20.88 0/1 APC hg19 chr5 112175907 112175907 + stopgain SNV C C G . pt1_T1_B Somatic p.S1539* NM_000038 c.4616C>G g.112175907C>G . pt1 T1 21.1 0/1 TP53 hg19 chr17 7578469 7578481 + frameshift_deletion Deletion CGGGTGCCGGGCGG CGGGTGCCGGGCGG C . pt1_T1_B Somatic p.P152Afs*14 NM_000546 c.454_466del13 g.7578469_7578481del13 . pt1 T1 21.61 0/1 BRAF hg19 chr7 140453136 140453136 + nonsynonymous_SNV SNV A A T rs113488022 pt1_T1_B Somatic p.V600E NM_004333 c.1799T>A g.140453136A>T . pt1 T1 31.66 0/1 BRAF hg19 chr7 140453155 140453155 + nonsynonymous_SNV SNV C C T . pt2_T1_B Somatic p.D594N NM_004333 c.1780G>A g.140453155C>T . pt2 T1 4.91 0/1 PIK3CA hg19 chr3 178952085 178952085 + nonsynonymous_SNV SNV A A G rs121913279 pt2_T1_B Somatic p.H1047R NM_006218 c.3140A>G g.178952085A>G . pt2 T1 5.02 0/1 WT1 hg19 chr11 32410611 32410611 + nonsynonymous_SNV SNV G G A . pt2_T1_B Somatic p.A516V NM_024426 c.1547C>T g.32410611G>A . pt2 T1 5.05 0/1 FLT1 hg19 chr13 29001999 29001999 + nonsynonymous_SNV SNV G G A . pt2_T1_B Somatic p.S389L NM_002019 c.1166C>T g.29001999G>A . pt2 T1 6.51 0/1 B2M hg19 chr15 45003745 45003745 + nonsynonymous_SNV SNV A A T . pt2_T1_B Somatic . NM_004048 c.1A>T g.45003745A>T . pt2 T1 9.02 0/1 ATM hg19 chr11 108236087 108236087 + nonsynonymous_SNV SNV G G A . pt2_T1_B Somatic p.R3008H NM_000051 c.9023G>A g.108236087G>A . pt2 T1 12.24 0/1 MLH1 hg19 chr3 37035072 37035072 + frameshift_deletion Deletion TG TG T . pt2_T2_B Somatic p.D12Tfs*5 NM_000249 c.34delG g.37035072delG . pt2 T2 0.32 0/1 HIST1H3B hg19 chr6 26032174 26032174 + frameshift_deletion Deletion AG AG A . pt2_T2_B Somatic p.P39Lfs*24 NM_003537 c.116delC g.26032174delG . pt2 T2 3.68 0/1 WT1 hg19 chr11 32410611 32410611 + nonsynonymous_SNV SNV G G A . pt2_T2_B Somatic p.A516V NM_024426 c.1547C>T g.32410611G>A . pt2 T2 3.85 0/1 BRAF hg19 chr7 140453155 140453155 + nonsynonymous_SNV SNV C C T . pt2_T2_B Somatic p.D594N NM_004333 c.1780G>A g.140453155C>T . pt2 T2 4.25 0/1 FLT1 hg19 chr13 29001999 29001999 + nonsynonymous_SNV SNV G G A . pt2_T2_B Somatic p.S389L NM_002019 c.1166C>T g.29001999G>A . pt2 T2 4.47 0/1 PIK3CA hg19 chr3 178952085 178952085 + nonsynonymous_SNV SNV A A G rs121913279 pt2_T2_B Somatic p.H1047R NM_006218 c.3140A>G g.178952085A>G . pt2 T2 5.15 0/1 B2M hg19 chr15 45003745 45003745 + nonsynonymous_SNV SNV A A T . pt2_T2_B Somatic p.M1L NM_004048 c.1A>T g.45003745A>T . pt2 T2 5.38 0/1 ATM hg19 chr11 108236087 108236087 + nonsynonymous_SNV SNV G G A . pt2_T2_B Somatic p.R3008H NM_000051 c.9023G>A g.108236087G>A . pt2 T2 10.8 0/1 KRAS hg19 chr12 25398284 25398284 + nonsynonymous_SNV SNV C C T rs121913529 pt3_T1_B Somatic p.G12D NM_033360 c.35G>A g.25398284C>T . pt3 T1 0.6 0/1 FBXW7 hg19 chr4 153249384 153249384 + nonsynonymous_SNV SNV C C T . pt3_T1_B Somatic p.R465H NM_033632 c.1394G>A g.153249384C>T . pt3 T1 0.49 0/1 MSH2 hg19 chr2 47690260 47690260 + stopgain SNV C C T rs63750936 pt6_T1_B Somatic p.Q493* NM_000251 c.1477C>T g.47690260C>T . pt6 T1 0.31 0/1 PRKAR1A hg19 chr17 66525088 66525088 + nonsynonymous_SNV SNV G G T . pt6_T1_B Somatic p.V283L NM_212471 c.847G>T g.66525088G>T . pt6 T1 15.55 0/1 APC hg19 chr5 112128143 112128143 + stopgain SNV C C T rs62619935 pt6_T1_B Somatic p.R216* NM_000038 c.646C>T g.112128143C>T . pt6 T1 27.72 0/1 APC hg19 chr5 112175204 112175204 + frameshift_deletion Deletion AG AG A . pt6_T1_B Somatic p.A1305Qfs*3 NM_000038 c.3913delG g.112175204delG . pt6 T1 31.06 0/1 KRAS hg19 chr12 25398284 25398284 + nonsynonymous_SNV SNV C C T rs121913529 pt6_T1_B Somatic p.G12D NM_033360 c.35G>A g.25398284C>T . pt6 T1 44.78 0/1 TP53 hg19 chr17 7578207 7578208 + frameshift_deletion Deletion CTA CTA C . pt6_T1_B Somatic p.H214Qfs*7 NM_000546 c.642_643delTA g.7578207_7578208delAT . pt6 T1 62.7 1/0 PRKAR1A hg19 chr17 66525088 66525088 + nonsynonymous_SNV SNV G G T . pt6_T2_B Somatic p.V283L NM_212471 c.847G>T g.66525088G>T . pt6 T2 4.66 0/1 APC hg19 chr5 112175204 112175204 + frameshift_deletion Deletion AG AG A . pt6_T2_B Somatic p.A1305Qfs*3 NM_000038 c.3913delG g.112175204delG . pt6 T2 7.7 0/1 APC hg19 chr5 112128143 112128143 + stopgain SNV C C T rs62619935 pt6_T2_B Somatic p.R216* NM_000038 c.646C>T g.112128143C>T . pt6 T2 8.88 0/1 KRAS hg19 chr12 25398284 25398284 + nonsynonymous_SNV SNV C C T rs121913529 pt6_T2_B Somatic p.G12D NM_033360 c.35G>A g.25398284C>T . pt6 T2 15.37 0/1 TP53 hg19 chr17 7578207 7578208 + frameshift_deletion Deletion CTA CTA C . pt6_T2_B Somatic p.H214Qfs*7 NM_000546 c.642_643delTA g.7578207_7578208delAT . pt6 T2 20.78 0/1 H3F3A hg19 chr1 226253478 226253478 + nonsynonymous_SNV SNV C C T . pt7_T1_B Somatic p.R84C NM_002107 c.250C>T g.226253478C>T . pt7 T1 1.02 0/1 EPHA7 hg19 chr6 93965743 93965743 + stopgain SNV G G A . pt7_T1_B Somatic p.Q729* NM_004440 c.2185C>T g.93965743G>A . pt7 T1 1.35 0/1 TP53 hg19 chr17 7578406 7578406 + nonsynonymous_SNV SNV C C T rs28934578 pt7_T1_B Somatic p.R175H NM_000546 c.524G>A g.7578406C>T . pt7 T1 1.48 0/1 SMAD4 hg19 chr18 48591919 48591919 + nonsynonymous_SNV SNV G G A rs377767347 pt7_T1_B Somatic p.R361H NM_005359 c.1082G>A g.48591919G>A . pt7 T1 1.56 0/1 KRAS hg19 chr12 25398284 25398284 + nonsynonymous_SNV SNV C C A rs121913529 pt7_T1_B Somatic p.G12V NM_033360 c.35G>T g.25398284C>A . pt7 T1 3.74 0/1 MSH2 hg19 chr2 47690260 47690260 + stopgain SNV C C T rs63750936 pt7_T2_B Somatic p.Q493* NM_000251 c.1477C>T g.47690260C>T . pt7 T2 0.3 0/1 MLH1 hg19 chr3 37038197 37038197 + frameshift_deletion Deletion TC TC T . pt7_T2_B Somatic p.R69Gfs*23 NM_000249 c.204delC g.37038197delC . pt7 T2 0.36 0/1 TP53 hg19 chr17 7578406 7578406 + nonsynonymous_SNV SNV C C T rs28934578 pt7_T2_B Somatic p.R175H NM_000546 c.524G>A g.7578406C>T . pt7 T2 1.03 0/1 SMAD4 hg19 chr18 48591919 48591919 + nonsynonymous_SNV SNV G G A rs377767347 pt7_T2_B Somatic p.R361H NM_005359 c.1082G>A g.48591919G>A . pt7 T2 1.07 0/1 KRAS hg19 chr12 25398284 25398284 + nonsynonymous_SNV SNV C C A rs121913529 pt7_T2_B Somatic p.G12V NM_033360 c.35G>T g.25398284C>A . pt7 T2 2.38 0/1 EZH2 hg19 chr7 148514321 148514321 + nonsynonymous_SNV SNV C C T . pt8_T2_B Somatic p.C468Y NM_004456 c.1403G>A g.148514321C>T . pt8 T2 1.1 0/1 EGFR hg19 chr7 55227884 55227884 + nonsynonymous_SNV SNV C C T rs377567759 pt9_T1_B Somatic p.R451C NM_005228 c.1351C>T g.55227884C>T . pt9 T1 0.31 0/1 TP53 hg19 chr17 7578190 7578190 + nonsynonymous_SNV SNV T T G rs121912666 pt9_T1_B Somatic p.Y220S NM_000546 c.659A>C g.7578190T>G . pt9 T1 60.63 1/0 TP53 hg19 chr17 7578190 7578190 + nonsynonymous_SNV SNV T T G rs121912666 pt9_T2_B Somatic p.Y220S NM_000546 c.659A>C g.7578190T>G . pt9 T2 21.04 0/1 KRAS hg19 chr12 25398284 25398284 + nonsynonymous_SNV SNV C C T rs121913529 pt10_T1_B Somatic p.G12D NM_033360 c.35G>A g.25398284C>T . pt10 T1 0.99 0/1 BRCA1 hg19 chr17 41226355 41226355 + nonsynonymous_SNV SNV T T G . pt10_T1_B Somatic p.Q1556H NM_007294 c.4668A>C g.41226355T>G . pt10 T1 1.47 0/1 SMARCA4 hg19 chr19 11141507 11141507 + nonsynonymous_SNV SNV G G A . pt11_T1_B Somatic p.G1162S NM_001128849 c.3484G>A g.11141507G>A . pt11 T1 1.77 0/1 APC hg19 chr5 112175411 112175411 + stopgain SNV G G T . pt11_T1_B Somatic p.E1374* NM_000038 c.4120G>T g.112175411G>T . pt11 T1 4.83 0/1 APC hg19 chr5 112174490 112174490 + stopgain SNV C C T rs137854571 pt11_T1_B Somatic p.Q1067* NM_000038 c.3199C>T g.112174490C>T . pt11 T1 8.5 0/1 TP53 hg19 chr17 7579401 7579410 + frameshift_deletion Deletion GGACAGAAGAT GGACAGAAGAT G . pt11_T1_B Somatic p.S95Lfs*25 NM_000546 c.282_291delATCTTCTGTC g.7579401_7579410delAAGATGACAG . pt11 T1 12.04 0/1 SPEN hg19 chr1 16255370 16255370 + nonsynonymous_SNV SNV G G A . pt12_T1_B Somatic p.V879I NM_015001 c.2635G>A g.16255370G>A . pt12 T1 15 0/1 SMARCA4 hg19 chr19 11168941 11168941 + nonsynonymous_SNV SNV C C T . pt12_T1_B Somatic p.R1511C NM_001128849 c.4531C>T g.11168941C>T . pt12 T1 19.34 0/1 KMT2D hg19 chr12 49423194 49423195 + frameshift_deletion Deletion TCA TCA T . pt12_T1_B Somatic p.E4689Gfs*7 NM_003482 c.14064_14065delTG g.49423194_49423195delCA . pt12 T1 20.13 0/1 ARID1A hg19 chr1 27106782 27106782 + frameshift_deletion Deletion AT AT A . pt12_T1_B Somatic p.N2131Kfs*4 NM_006015 c.6393delT g.27106782delT . pt12 T1 32.28 0/1 SMAD4 hg19 chr18 48591888 48591888 + nonsynonymous_SNV SNV G G T . pt12_T1_B Somatic p.D351Y NM_005359 c.1051G>T g.48591888G>T . pt12 T1 37.31 0/1 TP53 hg19 chr17 7578535 7578535 + nonsynonymous_SNV SNV T T C . pt12_T1_B Somatic p.K132R NM_000546 c.395A>G g.7578535T>C . pt12 T1 38.21 0/1 RNF43 hg19 chr17 56492917 56492918 + nonframeshift_substitution Complex GC GC AG . pt12_T1_B Somatic p.Q8* NM_017763 c.21_22delinsCT g.56492917_56492918delinsAG . pt12 T1 40.94 0/1 KDM5C hg19 chrX 53228065 53228065 + nonsynonymous_SNV SNV C C T . pt12_T1_B Somatic p.R750Q NM_004187 c.2249G>A g.53228065C>T . pt12 T1 52.9 1/0 KRAS hg19 chr12 25398284 25398284 + nonsynonymous_SNV SNV C C A rs121913529 pt12_T1_B Somatic p.G12V NM_033360 c.35G>T g.25398284C>A . pt12 T1 54.09 1/0 SPEN hg19 chr1 16255370 16255370 + nonsynonymous_SNV SNV G G A . pt12_T2_B Somatic p.V879I NM_015001 c.2635G>A g.16255370G>A . pt12 T2 1.4 0/1 TP53 hg19 chr17 7578535 7578535 + nonsynonymous_SNV SNV T T C . pt12_T2_B Somatic p.K132R NM_000546 c.395A>G g.7578535T>C . pt12 T2 1.58 0/1 SMARCA4 hg19 chr19 11168941 11168941 + nonsynonymous_SNV SNV C C T . pt12_T2_B Somatic p.R1511C NM_001128849 c.4531C>T g.11168941C>T . pt12 T2 1.74 0/1 KMT2D hg19 chr12 49423194 49423195 + frameshift_deletion Deletion TCA TCA T . pt12_T2_B Somatic p.E4689Gfs*7 NM_003482 c.14064_14065delTG g.49423194_49423195delCA . pt12 T2 2.4 0/1 SMAD4 hg19 chr18 48591888 48591888 + nonsynonymous_SNV SNV G G T . pt12_T2_B Somatic p.D351Y NM_005359 c.1051G>T g.48591888G>T . pt12 T2 2.26 0/1 RNF43 hg19 chr17 56492917 56492918 + nonframeshift_substitution Complex GC GC AG . pt12_T2_B Somatic p.Q8* NM_017763 c.21_22delinsCT g.56492917_56492918delinsAG . pt12 T2 3.16 0/1 ARID1A hg19 chr1 27106782 27106782 + frameshift_deletion Deletion AT AT A . pt12_T2_B Somatic p.N2131Kfs*4 NM_006015 c.6393delT g.27106782delT . pt12 T2 3.22 0/1 KDM5C hg19 chrX 53228065 53228065 + nonsynonymous_SNV SNV C C T . pt12_T2_B Somatic p.R750Q NM_004187 c.2249G>A g.53228065C>T . pt12 T2 4.68 0/1 KRAS hg19 chr12 25398284 25398284 + nonsynonymous_SNV SNV C C A rs121913529 pt12_T2_B Somatic p.G12V NM_033360 c.35G>T g.25398284C>A . pt12 T2 5.31 0/1 RET hg19 chr10 43620378 43620378 + nonsynonymous_SNV SNV C C T . pt13_T1_B Somatic p.P996L NM_020975 c.2987C>T g.43620378C>T . pt13 T1 1.12 0/1 IDH1 hg19 chr2 209113112 209113112 + nonsynonymous_SNV SNV C C T rs121913500 pt13_T2_B Somatic p.R132H NM_005896 c.395G>A g.209113112C>T . pt13 T2 0.32 0/1 MSH2 hg19 chr2 47635668 47635668 + stopgain SNV G G T . pt13_T2_B Somatic p.E114* NM_000251 c.340G>T g.47635668G>T . pt13 T2 0.33 0/1 PMS2 hg19 chr7 6045598 6045598 + stopgain SNV G G A . pt13_T2_B Somatic p.Q30* NM_000535 c.88C>T g.6045598G>A . pt13 T2 0.41 0/1 KMT2C hg19 chr7 151875096 151875096 + splicing SNV C C T . pt13_T2_B Somatic . NM_170606 c.7443-1G>A g.151875096C>T NM_170606:exon38:c.7443-1G>A pt13 T2 1 0/1 RET hg19 chr10 43620378 43620378 + nonsynonymous_SNV SNV C C T . pt13_T2_B Somatic p.P996L NM_020975 c.2987C>T g.43620378C>T . pt13 T2 1.27 0/1 PMS2 hg19 chr7 6048644 6048644 + stopgain SNV G G A . pt14_T2_B Somatic p.R3* NM_000535 c.7C>T g.6048644G>A . pt14 T2 0.38 0/1 KRAS hg19 chr12 25398284 25398284 + nonsynonymous_SNV SNV C C T rs121913529 pt15_T1_B Somatic p.G12D NM_033360 c.35G>A g.25398284C>T . pt15 T1 0.42 0/1 SMAD4 hg19 chr18 48603032 48603032 + stopgain SNV C C T rs377767360 pt15_T1_B Somatic p.R445* NM_005359 c.1333C>T g.48603032C>T . pt15 T1 0.45 0/1 BRCA1 hg19 chr17 41226450 41226450 + stopgain SNV G G A . pt15_T1_B Somatic p.Q1525* NM_007294 c.4573C>T g.41226450G>A . pt15 T1 49.26 0/1 RB1 hg19 chr13 48953730 48953730 + stopgain SNV C C T rs3092891 pt15_T2_B Somatic p.R445* NM_000321 c.1333C>T g.48953730C>T . pt15 T2 0.32 0/1 BRCA1 hg19 chr17 41226450 41226450 + stopgain SNV G G A . pt15_T2_B Somatic p.Q1525* NM_007294 c.4573C>T g.41226450G>A . pt15 T2 49.74 0/1 APC hg19 chr5 112173917 112173917 + stopgain SNV C C T rs121913333 pt16_T1_B Somatic p.R876* NM_000038 c.2626C>T g.112173917C>T . pt16 T1 2.3 0/1 SMAD4 hg19 chr18 48591904 48591904 + nonsynonymous_SNV SNV C C G . pt16_T1_B Somatic p.P356R NM_005359 c.1067C>G g.48591904C>G . pt16 T1 4.85 0/1 MYC hg19 chr8 128750526 128750526 + nonsynonymous_SNV SNV C C G . pt16_T1_B Somatic p.S21R NM_002467 c.63C>G g.128750526C>G . pt16 T1 6.55 0/1 NRAS hg19 chr1 115258745 115258745 + nonsynonymous_SNV SNV C C G rs121434595 pt16_T1_B Somatic p.G13R NM_002524 c.37G>C g.115258745C>G . pt16 T1 6.91 0/1 APC hg19 chr5 112175452 112175452 + stopgain SNV T T A . pt16_T1_B Somatic p.C1387* NM_000038 c.4161T>A g.112175452T>A . pt16 T1 7.83 0/1 TP53 hg19 chr17 7578236 7578236 + nonsynonymous_SNV SNV A A G . pt16_T1_B Somatic p.Y205H NM_000546 c.613T>C g.7578236A>G . pt16 T1 7.84 0/1 DNMT3A hg19 chr2 25457157 25457162 + nonframeshift_deletion Deletion CACGCAA CACGCAA C . pt16_T2_B Somatic p.F909_A910delFA NM_022552 c.2726_2731delTTGCGT g.25457157_25457162delCGCAAA . pt16 T2 1.68 0/1 APC hg19 chr5 112173917 112173917 + stopgain SNV C C T rs121913333 pt16_T2_B Somatic p.R876* NM_000038 c.2626C>T g.112173917C>T . pt16 T2 9.32 0/1 MYC hg19 chr8 128750526 128750526 + nonsynonymous_SNV SNV C C G . pt16_T2_B Somatic p.S21R NM_002467 c.63C>G g.128750526C>G . pt16 T2 13.77 0/1 NRAS hg19 chr1 115258745 115258745 + nonsynonymous_SNV SNV C C G rs121434595 pt16_T2_B Somatic p.G13R NM_002524 c.37G>C g.115258745C>G . pt16 T2 15.13 0/1 TP53 hg19 chr17 7578236 7578236 + nonsynonymous_SNV SNV A A G . pt16_T2_B Somatic p.Y205H NM_000546 c.613T>C g.7578236A>G . pt16 T2 19.33 0/1 SMAD4 hg19 chr18 48591904 48591904 + nonsynonymous_SNV SNV C C G . pt16_T2_B Somatic p.P356R NM_005359 c.1067C>G g.48591904C>G . pt16 T2 20.44 0/1 APC hg19 chr5 112175452 112175452 + stopgain SNV T T A . pt16_T2_B Somatic p.C1387* NM_000038 c.4161T>A g.112175452T>A . pt16 T2 27.61 0/1 SMAD4 hg19 chr18 48604769 48604769 + nonsynonymous_SNV SNV C C T . pt17_T1_B Somatic p.R531W NM_005359 c.1591C>T g.48604769C>T . pt17 T1 0.3 0/1 WT1 hg19 chr11 32456626 32456626 + nonsynonymous_SNV SNV C C G . pt17_T1_B Somatic p.G89A NM_024426 c.266G>C g.32456626C>G . pt17 T1 1.3 0/1 SDHA hg19 chr5 236681 236681 + nonsynonymous_SNV SNV T T A . pt17_T1_B Somatic p.C467S NM_004168 c.1399T>A g.236681T>A . pt17 T1 1.19 0/1 TP53 hg19 chr17 7577548 7577548 + nonsynonymous_SNV SNV C C T rs28934575 pt17_T1_B Somatic p.G245S NM_000546 c.733G>A g.7577548C>T . pt17 T1 6.89 0/1 KRAS hg19 chr12 25378562 25378562 + nonsynonymous_SNV SNV C C T rs121913527 pt17_T1_B Somatic p.A146T NM_033360 c.436G>A g.25378562C>T . pt17 T1 8.24 0/1 APC hg19 chr5 112175536 112175536 + frameshift_deletion Deletion GT GT G . pt17_T1_B Somatic p.S1415Rfs*4 NM_000038 c.4245delT g.112175536delT . pt17 T1 8.55 0/1 ATM hg19 chr11 108098503 108098503 + nonsynonymous_SNV SNV A A G . pt17_T1_B Somatic p.K25E NM_000051 c.73A>G g.108098503A>G . pt17 T1 12.83 0/1 RB1 hg19 chr13 48953730 48953730 + stopgain SNV C C T rs3092891 pt17_T2_B Somatic p.R445* NM_000321 c.1333C>T g.48953730C>T . pt17 T2 0.35 0/1 PALB2 hg19 chr16 23625374 23625374 + nonsynonymous_SNV SNV A A G . pt17_T2_B Somatic p.I1051T NM_024675 c.3152T>C g.23625374A>G . pt17 T2 1.02 0/1 KRAS hg19 chr12 25378562 25378562 + nonsynonymous_SNV SNV C C T rs121913527 pt17_T2_B Somatic p.A146T NM_033360 c.436G>A g.25378562C>T . pt17 T2 1.47 0/1 APC hg19 chr5 112175536 112175536 + frameshift_deletion Deletion GT GT G . pt17_T2_B Somatic p.S1415Rfs*4 NM_000038 c.4245delT g.112175536delT . pt17 T2 2.32 0/1 ATM hg19 chr11 108098503 108098503 + nonsynonymous_SNV SNV A A G . pt17_T2_B Somatic p.K25E NM_000051 c.73A>G g.108098503A>G . pt17 T2 2.59 0/1 TP53 hg19 chr17 7577548 7577548 + nonsynonymous_SNV SNV C C T rs28934575 pt17_T2_B Somatic p.G245S NM_000546 c.733G>A g.7577548C>T . pt17 T2 2.75 0/1 MSH2 hg19 chr2 47641474 47641474 + stopgain SNV G G T rs63750276 pt18_T1_B Somatic p.G287* NM_000251 c.859G>T g.47641474G>T . pt18 T1 0.4 0/1 MSH2 hg19 chr2 47641483 47641483 + stopgain SNV G G T . pt18_T1_B Somatic p.E290* NM_000251 c.868G>T g.47641483G>T . pt18 T1 0.35 0/1 IDH2 hg19 chr15 90645601 90645601 + nonsynonymous_SNV SNV C C T . pt18_T1_B Somatic p.V8M NM_002168 c.22G>A g.90645601C>T . pt18 T1 1.12 0/1 MED12 hg19 chrX 70338609 70338609 + nonsynonymous_SNV SNV C C T . pt19_T1_B Somatic p.A2V NM_005120 c.5C>T g.70338609C>T . pt19 T1 1.01 0/1 NOTCH1 hg19 chr9 139440184 139440184 + nonsynonymous_SNV SNV C C T . pt19_T1_B Somatic p.A19T NM_017617 c.55G>A g.139440184C>T . pt19 T1 1.4 0/1 ARID1A hg19 chr1 27023025 27023025 + nonsynonymous_SNV SNV C C T . pt19_T1_B Somatic p.A44V NM_006015 c.131C>T g.27023025C>T . pt19 T1 1.48 0/1 KMT2C hg19 chr7 151842259 151842259 + nonsynonymous_SNV SNV T T C . pt21_T1_B Somatic p.H4718R NM_170606 c.14153A>G g.151842259T>C . pt21 T1 1.35 0/1 KMT2D hg19 chr12 49416648 49416648 + nonsynonymous_SNV SNV G G T . pt21_T1_B Somatic p.L5355M NM_003482 c.16063C>A g.49416648G>T . pt21 T1 1.35 0/1 CDKN2B hg19 chr9 22006000 22006000 + nonsynonymous_SNV SNV C C T . pt21_T1_B Somatic p.A135T NM_004936 c.403G>A g.22006000C>T . pt21 T1 1.69 0/1 KMT2D hg19 chr12 49418651 49418651 + nonsynonymous_SNV SNV A A G . pt21_T1_B Somatic p.L5288P NM_003482 c.15863T>C g.49418651A>G . pt21 T1 1.77 0/1 RARA hg19 chr17 38511524 38511524 + nonsynonymous_SNV SNV A A G . pt21_T1_B Somatic p.D341G NM_000964 c.1022A>G g.38511524A>G . pt21 T1 2.04 0/1 NOTCH3 hg19 chr19 15281259 15281259 + nonsynonymous_SNV SNV C C T . pt21_T1_B Somatic p.R1666Q NM_000435 c.4997G>A g.15281259C>T . pt21 T1 2.15 0/1 KMT2D hg19 chr12 49447845 49447845 + frameshift_insertion Insertion A A AT . pt21_T1_B Somatic p.C197Mfs*23 NM_003482 c.588_589insA g.49447845_49447846insT . pt21 T1 3.23 0/1 RPTOR hg19 chr17 78933989 78933989 + nonsynonymous_SNV SNV A A G . pt21_T1_B Somatic p.M1197V NM_020761 c.3589A>G g.78933989A>G . pt21 T1 3.31 0/1 BRD4 hg19 chr19 15367969 15367969 + nonsynonymous_SNV SNV G G A . pt21_T1_B Somatic p.R453C NM_058243 c.1357C>T g.15367969G>A . pt21 T1 6.43 0/1 KDM5C hg19 chrX 53226066 53226066 + nonsynonymous_SNV SNV G G A . pt21_T1_B Somatic p.A928V NM_004187 c.2783C>T g.53226066G>A . pt21 T1 6.73 0/1 TBX3 hg19 chr12 115112230 115112230 + nonsynonymous_SNV SNV C C T . pt21_T1_B Somatic p.A504T NM_016569 c.1510G>A g.115112230C>T . pt21 T1 7.2 0/1 PRDM1 hg19 chr6 106553461 106553461 + nonsynonymous_SNV SNV C C T . pt21_T1_B Somatic p.R476W NM_001198 c.1426C>T g.106553461C>T . pt21 T1 7.22 0/1 IKBKE hg19 chr1 206646649 206646649 + nonsynonymous_SNV SNV C C T . pt21_T1_B Somatic p.R27C NM_014002 c.79C>T g.206646649C>T . pt21 T1 7.23 0/1 PRKCI hg19 chr3 169977760 169977760 + nonsynonymous_SNV SNV A A G . pt21_T1_B Somatic p.D76G NM_002740 c.227A>G g.169977760A>G . pt21 T1 8.95 0/1 TERT hg19 chr5 1294574 1294574 + nonsynonymous_SNV SNV G G A . pt21_T1_B Somatic p.R143C NM_198253 c.427C>T g.1294574G>A . pt21 T1 11.44 0/1 SMO hg19 chr7 128848687 128848687 + nonsynonymous_SNV SNV G G A . pt21_T1_B Somatic p.R451H NM_005631 c.1352G>A g.128848687G>A . pt21 T1 27.12 0/1 KMT2C hg19 chr7 151845261 151845261 + nonsynonymous_SNV SNV C C T . pt21_T1_B Somatic p.R4584Q NM_170606 c.13751G>A g.151845261C>T . pt21 T1 29.56 0/1 PIK3CG hg19 chr7 106508733 106508733 + nonsynonymous_SNV SNV G G A . pt21_T1_B Somatic p.A243T NM_002649 c.727G>A g.106508733G>A . pt21 T1 30.36 0/1 IRS2 hg19 chr13 110438336 110438341 + nonframeshift_deletion Deletion GGTTGTT GGTTGTT G . pt21_T1_B Somatic p.N27_N28delNN NM_003749 c.79_84delAACAAC g.110438336_110438341delTTGTTG . pt21 T1 30.94 0/1 ARID2 hg19 chr12 46211569 46211569 + nonsynonymous_SNV SNV G G A . pt21_T1_B Somatic p.V179I NM_152641 c.535G>A g.46211569G>A . pt21 T1 36.57 0/1 NF1 hg19 chr17 29586101 29586101 + nonsynonymous_SNV SNV C C T . pt21_T1_B Somatic p.R1441W NM_000267 c.4321C>T g.29586101C>T . pt21 T1 36.59 0/1 FBXW7 hg19 chr4 153249385 153249385 + nonsynonymous_SNV SNV G G A . pt21_T1_B Somatic p.R465C NM_033632 c.1393C>T g.153249385G>A . pt21 T1 37.21 0/1 APC hg19 chr5 112174631 112174631 + stopgain SNV C C T rs121913331 pt21_T1_B Somatic p.R1114* NM_000038 c.3340C>T g.112174631C>T . pt21 T1 39.47 0/1 KRAS hg19 chr12 25398281 25398281 + nonsynonymous_SNV SNV C C T rs112445441 pt21_T1_B Somatic p.G13D NM_033360 c.38G>A g.25398281C>T . pt21 T1 39.67 0/1 SMAD2 hg19 chr18 45395718 45395718 + nonsynonymous_SNV SNV C C T . pt21_T1_B Somatic p.S139N NM_001003652 c.416G>A g.45395718C>T . pt21 T1 41.15 0/1 ERBB3 hg19 chr12 56478854 56478854 + nonsynonymous_SNV SNV G G A . pt21_T1_B Somatic p.V104M NM_001982 c.310G>A g.56478854G>A . pt21 T1 41.28 0/1 ROS1 hg19 chr6 117709036 117709036 + nonsynonymous_SNV SNV T T C . pt21_T1_B Somatic p.S641G NM_002944 c.1921A>G g.117709036T>C . pt21 T1 41.42 0/1 FAT1 hg19 chr4 187628583 187628583 + nonsynonymous_SNV SNV G G T . pt21_T1_B Somatic p.P800H NM_005245 c.2399C>A g.187628583G>T . pt21 T1 42.27 0/1 APC hg19 chr5 112175207 112175207 + stopgain SNV G G T rs121913462 pt21_T1_B Somatic p.E1306* NM_000038 c.3916G>T g.112175207G>T . pt21 T1 44.22 0/1 TSC2 hg19 chr16 2135264 2135264 + nonsynonymous_SNV SNV G G A . pt21_T1_B Somatic p.D1535N NM_000548 c.4603G>A g.2135264G>A . pt21 T1 82.21 1月1日 MSH2 hg19 chr2 47672749 47672750 + frameshift_deletion Deletion CTT CTT C . pt21_T1_B Somatic p.F447Lfs*20 NM_000251 c.1339_1340delTT g.47672749_47672750delTT . pt21 T1 83.69 1月1日 TBX3 hg19 chr12 115112230 115112230 + nonsynonymous_SNV SNV C C T . pt21_T2_B Somatic p.A504T NM_016569 c.1510G>A g.115112230C>T . pt21 T2 1.06 0/1 RARA hg19 chr17 38511524 38511524 + nonsynonymous_SNV SNV A A G . pt21_T2_B Somatic p.D341G NM_000964 c.1022A>G g.38511524A>G . pt21 T2 1.31 0/1 BRD4 hg19 chr19 15367969 15367969 + nonsynonymous_SNV SNV G G A . pt21_T2_B Somatic p.R453C NM_058243 c.1357C>T g.15367969G>A . pt21 T2 1.75 0/1 RPTOR hg19 chr17 78933989 78933989 + nonsynonymous_SNV SNV A A G . pt21_T2_B Somatic p.M1197V NM_020761 c.3589A>G g.78933989A>G . pt21 T2 2.09 0/1 CDKN2B hg19 chr9 22006000 22006000 + nonsynonymous_SNV SNV C C T . pt21_T2_B Somatic p.A135T NM_004936 c.403G>A g.22006000C>T . pt21 T2 2.28 0/1 KMT2D hg19 chr12 49447845 49447845 + frameshift_insertion Insertion A A AT . pt21_T2_B Somatic p.C197Mfs*23 NM_003482 c.588_589insA g.49447845_49447846insT . pt21 T2 2.51 0/1 TERT hg19 chr5 1294574 1294574 + nonsynonymous_SNV SNV G G A . pt21_T2_B Somatic p.R143C NM_198253 c.427C>T g.1294574G>A . pt21 T2 2.78 0/1 PRKCI hg19 chr3 169977760 169977760 + nonsynonymous_SNV SNV A A G . pt21_T2_B Somatic p.D76G NM_002740 c.227A>G g.169977760A>G . pt21 T2 2.91 0/1 KDM5C hg19 chrX 53226066 53226066 + nonsynonymous_SNV SNV G G A . pt21_T2_B Somatic p.A928V NM_004187 c.2783C>T g.53226066G>A . pt21 T2 4.67 0/1 KRAS hg19 chr12 25398281 25398281 + nonsynonymous_SNV SNV C C T rs112445441 pt21_T2_B Somatic p.G13D NM_033360 c.38G>A g.25398281C>T . pt21 T2 6.1 0/1 SMAD2 hg19 chr18 45395718 45395718 + nonsynonymous_SNV SNV C C T . pt21_T2_B Somatic p.S139N NM_001003652 c.416G>A g.45395718C>T . pt21 T2 6.6 0/1 NF1 hg19 chr17 29586101 29586101 + nonsynonymous_SNV SNV C C T . pt21_T2_B Somatic p.R1441W NM_000267 c.4321C>T g.29586101C>T . pt21 T2 6.09 0/1 FAT1 hg19 chr4 187628583 187628583 + nonsynonymous_SNV SNV G G T . pt21_T2_B Somatic p.P800H NM_005245 c.2399C>A g.187628583G>T . pt21 T2 6.9 0/1 ERBB3 hg19 chr12 56478854 56478854 + nonsynonymous_SNV SNV G G A . pt21_T2_B Somatic p.V104M NM_001982 c.310G>A g.56478854G>A . pt21 T2 6.13 0/1 FBXW7 hg19 chr4 153249385 153249385 + nonsynonymous_SNV SNV G G A . pt21_T2_B Somatic p.R465C NM_033632 c.1393C>T g.153249385G>A . pt21 T2 6.36 0/1 ROS1 hg19 chr6 117709036 117709036 + nonsynonymous_SNV SNV T T C . pt21_T2_B Somatic p.S641G NM_002944 c.1921A>G g.117709036T>C . pt21 T2 6.46 0/1 ARID2 hg19 chr12 46211569 46211569 + nonsynonymous_SNV SNV G G A . pt21_T2_B Somatic p.V179I NM_152641 c.535G>A g.46211569G>A . pt21 T2 6.76 0/1 SMO hg19 chr7 128848687 128848687 + nonsynonymous_SNV SNV G G A . pt21_T2_B Somatic p.R451H NM_005631 c.1352G>A g.128848687G>A . pt21 T2 7.32 0/1 PIK3CG hg19 chr7 106508733 106508733 + nonsynonymous_SNV SNV G G A . pt21_T2_B Somatic p.A243T NM_002649 c.727G>A g.106508733G>A . pt21 T2 7.37 0/1 KMT2C hg19 chr7 151845261 151845261 + nonsynonymous_SNV SNV C C T . pt21_T2_B Somatic p.R4584Q NM_170606 c.13751G>A g.151845261C>T . pt21 T2 7.46 0/1 APC hg19 chr5 112174631 112174631 + stopgain SNV C C T rs121913331 pt21_T2_B Somatic p.R1114* NM_000038 c.3340C>T g.112174631C>T . pt21 T2 7.47 0/1 APC hg19 chr5 112175207 112175207 + stopgain SNV G G T rs121913462 pt21_T2_B Somatic p.E1306* NM_000038 c.3916G>T g.112175207G>T . pt21 T2 8.08 0/1 TSC2 hg19 chr16 2135264 2135264 + nonsynonymous_SNV SNV G G A . pt21_T2_B Somatic p.D1535N NM_000548 c.4603G>A g.2135264G>A . pt21 T2 13.23 0/1 MSH2 hg19 chr2 47672749 47672750 + frameshift_deletion Deletion CTT CTT C . pt21_T2_B Somatic p.F447Lfs*20 NM_000251 c.1339_1340delTT g.47672749_47672750delTT . pt21 T2 13.62 0/1 KRAS hg19 chr12 25380282 25380282 + nonsynonymous_SNV SNV G G A rs104886029 pt22_T1_B Somatic p.A59V NM_033360 c.176C>T g.25380282G>A . pt22 T1 0.3 0/1 CHEK2 hg19 chr22 29099492 29099492 + splicing SNV C C T . pt22_T2_B Somatic . NM_007194 c.908+1G>A g.29099492C>T "NM_145862:exon9:c.908+1G>A,NM_007194:exon9:c.908+1G>A,NM_001257387:exon10:c.245+1G>A,NM_001005735:exon10:c.1037+1G>A" pt22 T2 1.43 0/1 MSH2 hg19 chr2 47643534 47643534 + stopgain SNV C C T . pt23_T1_B Somatic p.Q348* NM_000251 c.1042C>T g.47643534C>T . pt23 T1 0.35 0/1 APC hg19 chr5 112174379 112174379 + stopgain SNV A A T . pt23_T1_B Somatic p.K1030* NM_000038 c.3088A>T g.112174379A>T . pt23 T1 1.08 0/1 KRAS hg19 chr12 25378561 25378561 + nonsynonymous_SNV SNV G G A . pt23_T1_B Somatic p.A146V NM_033360 c.437C>T g.25378561G>A . pt23 T1 2.41 0/1 MLH1 hg19 chr3 37089161 37089161 + stopgain SNV T T A . pt23_T2_B Somatic p.L628* NM_000249 c.1883T>A g.37089161T>A . pt23 T2 0.39 0/1 PDGFRB hg19 chr5 149510145 149510145 + nonsynonymous_SNV SNV G G A . pt23_T2_B Somatic p.P442S NM_002609 c.1324C>T g.149510145G>A . pt23 T2 1.12 0/1 CHEK2 hg19 chr22 29107960 29107960 + stopgain SNV A A T . pt23_T2_B Somatic p.C243* NM_007194 c.729T>A g.29107960A>T . pt23 T2 1.52 0/1 BRAF hg19 chr7 140453145 140453145 + nonsynonymous_SNV SNV A A T rs121913366 pt24_T1_B Somatic p.L597Q NM_004333 c.1790T>A g.140453145A>T . pt24 T1 0.45 0/1 KRAS hg19 chr12 25398284 25398284 + nonsynonymous_SNV SNV C C G rs121913529 pt24_T1_B Somatic p.G12A NM_033360 c.35G>C g.25398284C>G . pt24 T1 1.54 0/1 BRAF hg19 chr7 140453145 140453145 + nonsynonymous_SNV SNV A A T rs121913366 pt24_T2_B Somatic p.L597Q NM_004333 c.1790T>A g.140453145A>T . pt24 T2 1.49 0/1 KRAS hg19 chr12 25398284 25398284 + nonsynonymous_SNV SNV C C G rs121913529 pt24_T2_B Somatic p.G12A NM_033360 c.35G>C g.25398284C>G . pt24 T2 3.87 0/1 KRAS hg19 chr12 25398284 25398284 + nonsynonymous_SNV SNV C C T rs121913529 pt25_T1_B Somatic p.G12D NM_033360 c.35G>A g.25398284C>T . pt25 T1 34.04 0/1 TP53 hg19 chr17 7578212 7578212 + stopgain SNV G G A . pt25_T1_B Somatic p.R213* NM_000546 c.637C>T g.7578212G>A . pt25 T1 35.29 0/1 TP53 hg19 chr17 7576897 7576897 + stopgain SNV G G A . pt25_T1_B Somatic p.Q317* NM_000546 c.949C>T g.7576897G>A . pt25 T1 36.35 0/1 APC hg19 chr5 112151204 112151204 + stopgain SNV C C T . pt25_T1_B Somatic p.R283* NM_000038 c.847C>T g.112151204C>T . pt25 T1 56.27 1/0 MLH1 hg19 chr3 37083774 37083774 + stopgain SNV C C A . pt25_T2_B Somatic p.Y561* NM_000249 c.1683C>A g.37083774C>A . pt25 T2 0.34 0/1 RB1 hg19 chr13 48954210 48954210 + stopgain SNV C C T . pt26_T2_B Somatic p.Q471* NM_000321 c.1411C>T g.48954210C>T . pt26 T2 0.36 0/1 MSH2 hg19 chr2 47705428 47705428 + stopgain SNV C C A rs63751155 pt26_T2_B Somatic p.S743* NM_000251 c.2228C>A g.47705428C>A . pt26 T2 0.38 0/1 TP53 hg19 chr17 7577578 7577580 + nonframeshift_deletion Deletion AGTT AGTT A . pt26_T2_B Somatic p.N235delN NM_000546 c.703_705delAAC g.7577578_7577580delTGT . pt26 T2 1.36 0/1 APC hg19 chr5 112151204 112151204 + stopgain SNV C C T . pt26_T2_B Somatic p.R283* NM_000038 c.847C>T g.112151204C>T . pt26 T2 1.69 0/1 PIK3CB hg19 chr3 138374293 138374293 + nonsynonymous_SNV SNV C C T . pt26_T2_B Somatic p.E1051K NM_006219 c.3151G>A g.138374293C>T . pt26 T2 2.23 0/1 APC hg19 chr5 112173917 112173917 + stopgain SNV C C T rs121913333 pt27_T1_B Somatic p.R876* NM_000038 c.2626C>T g.112173917C>T . pt27 T1 1.4 0/1 ERBB2 hg19 chr17 37881000 37881000 + nonsynonymous_SNV SNV G G T rs121913471 pt27_T1_B Somatic p.V777L NM_004448 c.2329G>T g.37881000G>T . pt27 T1 1.36 0/1 AMER1 hg19 chrX 63412095 63412095 + stopgain SNV G G A rs137852217 pt27_T1_B Somatic p.R358* NM_152424 c.1072C>T g.63412095G>A . pt27 T1 1.75 0/1 KRAS hg19 chr12 25398285 25398285 + nonsynonymous_SNV SNV C C T rs121913530 pt27_T1_B Somatic p.G12S NM_033360 c.34G>A g.25398285C>T . pt27 T1 4.08 0/1 SMARCA4 hg19 chr19 11170441 11170441 + nonsynonymous_SNV SNV T T G . pt27_T2_B Somatic p.S1582A NM_001128849 c.4744T>G g.11170441T>G . pt27 T2 1.15 0/1 APC hg19 chr5 112173917 112173917 + stopgain SNV C C T rs121913333 pt27_T2_B Somatic p.R876* NM_000038 c.2626C>T g.112173917C>T . pt27 T2 1.43 0/1 AMER1 hg19 chrX 63412095 63412095 + stopgain SNV G G A rs137852217 pt27_T2_B Somatic p.R358* NM_152424 c.1072C>T g.63412095G>A . pt27 T2 2.04 0/1 SMAD3 hg19 chr15 67473722 67473722 + nonsynonymous_SNV SNV C C T . pt27_T2_B Somatic p.R268C NM_005902 c.802C>T g.67473722C>T . pt27 T2 2.27 0/1 ERBB2 hg19 chr17 37881000 37881000 + nonsynonymous_SNV SNV G G T rs121913471 pt27_T2_B Somatic p.V777L NM_004448 c.2329G>T g.37881000G>T . pt27 T2 3.45 0/1 KRAS hg19 chr12 25398285 25398285 + nonsynonymous_SNV SNV C C T rs121913530 pt27_T2_B Somatic p.G12S NM_033360 c.34G>A g.25398285C>T . pt27 T2 4.37 0/1 NUP93 hg19 chr16 56871601 56871601 + nonsynonymous_SNV SNV G G A . pt29_T1_B Somatic p.E661K NM_014669 c.1981G>A g.56871601G>A . pt29 T1 1.18 0/1 LATS1 hg19 chr6 150001188 150001188 + stopgain SNV G G A . pt29_T1_B Somatic p.R806* NM_004690 c.2416C>T g.150001188G>A . pt29 T1 1.73 0/1 KMT2C hg19 chr7 151845435 151845435 + nonsynonymous_SNV SNV T T C . pt29_T1_B Somatic p.Y4526C NM_170606 c.13577A>G g.151845435T>C . pt29 T1 1.91 0/1 TP53 hg19 chr17 7579342 7579342 + frameshift_insertion Insertion G G GAATGC . pt29_T1_B Somatic p.S116Cfs*9 NM_000546 c.342_346dupGCATT g.7579343_7579347dupTGCAA . pt29 T1 3.22 0/1 SMARCA4 hg19 chr19 11100004 11100004 + nonsynonymous_SNV SNV G G A . pt29_T2_B Somatic p.R377H NM_001128849 c.1130G>A g.11100004G>A . pt29 T2 8.7 0/1 APC hg19 chr5 112173917 112173917 + stopgain SNV C C T rs121913333 pt29_T2_B Somatic p.R876* NM_000038 c.2626C>T g.112173917C>T . pt29 T2 12.47 0/1 KMT2C hg19 chr7 151845435 151845435 + nonsynonymous_SNV SNV T T C . pt29_T2_B Somatic p.Y4526C NM_170606 c.13577A>G g.151845435T>C . pt29 T2 13.15 0/1 LATS1 hg19 chr6 150001188 150001188 + stopgain SNV G G A . pt29_T2_B Somatic p.R806* NM_004690 c.2416C>T g.150001188G>A . pt29 T2 13.34 0/1 TP53 hg19 chr17 7579342 7579342 + frameshift_insertion Insertion G G GAATGC . pt29_T2_B Somatic p.S116Cfs*9 NM_000546 c.342_346dupGCATT g.7579343_7579347dupTGCAA . pt29 T2 22.94 0/1 SMAD2 hg19 chr18 45368211 45368211 + stopgain SNV G G C . pt30_T1_B Somatic p.S464* NM_001003652 c.1391C>G g.45368211G>C . pt30 T1 36.42 0/1 SMAD2 hg19 chr18 45371712 45371712 + stopgain SNV G G A . pt30_T1_B Somatic p.R427* NM_001003652 c.1279C>T g.45371712G>A . pt30 T1 38.84 0/1 EPHB1 hg19 chr3 134851646 134851646 + nonsynonymous_SNV SNV G G A . pt30_T1_B Somatic p.R351Q NM_004441 c.1052G>A g.134851646G>A . pt30 T1 41.24 0/1 PPP2R1A hg19 chr19 52715982 52715982 + nonsynonymous_SNV SNV C C T . pt30_T1_B Somatic p.R183W NM_014225 c.547C>T g.52715982C>T . pt30 T1 55.24 1/0 KRAS hg19 chr12 25398284 25398284 + nonsynonymous_SNV SNV C C T rs121913529 pt30_T1_B Somatic p.G12D NM_033360 c.35G>A g.25398284C>T . pt30 T1 57.41 1/0 SOX9 hg19 chr17 70119081 70119087 + frameshift_deletion Deletion CATGAGCG CATGAGCG C . pt30_T1_B Somatic p.M218Rfs*33 NM_000346 c.653_659delTGAGCGA g.70119081_70119087delTGAGCGA . pt30 T1 71.76 1/0 APC hg19 chr5 112128180 112128180 + frameshift_insertion Insertion T T TA . pt30_T1_B Somatic p.L229Tfs*23 NM_000038 c.684dupA g.112128181dupA . pt30 T1 82.18 1月1日 PTPRT hg19 chr20 40748606 40748606 + stopgain SNV G G T . pt30_T2_B Somatic p.Y970* NM_133170 c.2910C>A g.40748606G>T . pt30 T2 2.96 0/1 SMAD2 hg19 chr18 45368211 45368211 + stopgain SNV G G C . pt30_T2_B Somatic p.S464* NM_001003652 c.1391C>G g.45368211G>C . pt30 T2 24.9 0/1 SMAD2 hg19 chr18 45371712 45371712 + stopgain SNV G G A . pt30_T2_B Somatic p.R427* NM_001003652 c.1279C>T g.45371712G>A . pt30 T2 25.57 0/1 EPHB1 hg19 chr3 134851646 134851646 + nonsynonymous_SNV SNV G G A . pt30_T2_B Somatic p.R351Q NM_004441 c.1052G>A g.134851646G>A . pt30 T2 28.28 0/1 PPP2R1A hg19 chr19 52715982 52715982 + nonsynonymous_SNV SNV C C T . pt30_T2_B Somatic p.R183W NM_014225 c.547C>T g.52715982C>T . pt30 T2 35.35 0/1 KRAS hg19 chr12 25398284 25398284 + nonsynonymous_SNV SNV C C T rs121913529 pt30_T2_B Somatic p.G12D NM_033360 c.35G>A g.25398284C>T . pt30 T2 43.16 0/1 SOX9 hg19 chr17 70119081 70119087 + frameshift_deletion Deletion CATGAGCG CATGAGCG C . pt30_T2_B Somatic p.M218Rfs*33 NM_000346 c.653_659delTGAGCGA g.70119081_70119087delTGAGCGA . pt30 T2 52.94 0/1 APC hg19 chr5 112128180 112128180 + frameshift_insertion Insertion T T TA . pt30_T2_B Somatic p.L229Tfs*23 NM_000038 c.684dupA g.112128181dupA . pt30 T2 54.7 1/0 KRAS hg19 chr12 25398284 25398284 + nonsynonymous_SNV SNV C C T rs121913529 pt31_T1_B Somatic p.G12D NM_033360 c.35G>A g.25398284C>T . pt31 T1 1.32 0/1 APC hg19 chr5 112175358 112175358 + stopgain SNV C C G . pt31_T1_B Somatic p.S1356* NM_000038 c.4067C>G g.112175358C>G . pt31 T1 1.62 0/1 SMAD4 hg19 chr18 48603050 48603074 + frameshift_deletion Deletion AGCAGCAGGCGGCTACTGCACAAGCT AGCAGCAGGCGGCTACTGCACAAGCT A . pt31_T1_B Somatic p.A451Lfs*17 NM_005359 c.1351_1375del25 g.48603050_48603074del25 . pt31 T1 1.72 0/1 GRIN2A hg19 chr16 9858493 9858493 + nonsynonymous_SNV SNV G G A . pt31_T1_B Somatic p.R970W NM_001134407 c.2908C>T g.9858493G>A . pt31 T1 1.73 0/1 EP300 hg19 chr22 41551007 41551007 + nonsynonymous_SNV SNV C C A . pt31_T2_B Somatic p.P1051T NM_001429 c.3151C>A g.41551007C>A . pt31 T2 1.23 0/1 KRAS hg19 chr12 25380282 25380282 + nonsynonymous_SNV SNV G G T . pt32_T1_B Somatic p.A59E NM_033360 c.176C>A g.25380282G>T . pt32 T1 0.31 0/1 MSH6 hg19 chr2 48026957 48026957 + stopgain SNV C C A rs63750564 pt32_T1_B Somatic p.S612* NM_000179 c.1835C>A g.48026957C>A . pt32 T1 0.32 0/1 SMAD4 hg19 chr18 48591902 48591902 + nonsynonymous_SNV SNV C C A . pt32_T1_B Somatic p.D355E NM_005359 c.1065C>A g.48591902C>A . pt32 T1 0.35 0/1 MLH1 hg19 chr3 37048491 37048491 + stopgain SNV C C A . pt32_T1_B Somatic p.Y130* NM_000249 c.390C>A g.37048491C>A . pt32 T1 0.47 0/1 U2AF1 hg19 chr21 44521525 44521525 + nonsynonymous_SNV SNV G G T . pt32_T1_B Somatic p.N50K NM_001025203 c.150C>A g.44521525G>T . pt32 T1 1.03 0/1 PMS2 hg19 chr7 6036980 6036981 + nonframeshift_substitution Complex GG GG CT . pt32_T1_B Somatic p.S260* NM_000535 c.779_780delinsAG g.6036980_6036981delinsCT . pt32 T1 1.19 0/1 APC hg19 chr5 112175174 112175174 + stopgain SNV G G T . pt32_T1_B Somatic p.E1295* NM_000038 c.3883G>T g.112175174G>T . pt32 T1 2.14 0/1 KRAS hg19 chr12 25398284 25398284 + nonsynonymous_SNV SNV C C G rs121913529 pt32_T1_B Somatic p.G12A NM_033360 c.35G>C g.25398284C>G . pt32 T1 3.06 0/1 PIK3CA hg19 chr3 178952085 178952085 + nonsynonymous_SNV SNV A A G rs121913279 pt33_T1_B Somatic p.H1047R NM_006218 c.3140A>G g.178952085A>G . pt33 T1 0.59 0/1 GRIN2A hg19 chr16 9862903 9862903 + stopgain SNV G G T . pt33_T1_B Somatic p.C800* NM_001134407 c.2400C>A g.9862903G>T . pt33 T1 13 0/1 APC hg19 chr5 112175639 112175639 + stopgain SNV C C T rs121913332 pt33_T1_B Somatic p.R1450* NM_000038 c.4348C>T g.112175639C>T . pt33 T1 13.8 0/1 ATM hg19 chr11 108224594 108224594 + nonsynonymous_SNV SNV G G A . pt33_T1_B Somatic p.G2925S NM_000051 c.8773G>A g.108224594G>A . pt33 T1 13.96 0/1 KRAS hg19 chr12 25398284 25398284 + nonsynonymous_SNV SNV C C T rs121913529 pt33_T1_B Somatic p.G12D NM_033360 c.35G>A g.25398284C>T . pt33 T1 19.99 0/1 APC hg19 chr5 112162891 112162891 + stopgain SNV C C T rs137854580 pt33_T1_B Somatic p.R499* NM_000038 c.1495C>T g.112162891C>T . pt33 T1 22.27 0/1 PTPRT hg19 chr20 41514530 41514530 + nonsynonymous_SNV SNV C C A . pt33_T1_B Somatic p.S44I NM_133170 c.131G>T g.41514530C>A . pt33 T1 36.05 0/1 HNF1A hg19 chr12 121431482 121431482 + nonsynonymous_SNV SNV G G A . pt34_T1_B Somatic p.R229Q NM_000545 c.686G>A g.121431482G>A . pt34 T1 2.41 0/1 GATA3 hg19 chr10 8100469 8100469 + nonsynonymous_SNV SNV C C T . pt34_T1_B Somatic p.P148L NM_001002295 c.443C>T g.8100469C>T . pt34 T1 3.45 0/1 APC hg19 chr5 112164586 112164586 + stopgain SNV C C T rs137854573 pt34_T1_B Somatic p.R554* NM_000038 c.1660C>T g.112164586C>T . pt34 T1 4.23 0/1 GNAS hg19 chr20 57429860 57429860 + frameshift_insertion Insertion G G GGCGA . pt34_T1_B Somatic p.A514Gfs*55 NM_080425 c.1540_1541insGCGA g.57429860_57429861insGCGA . pt34 T1 17.23 0/1 KMT2D hg19 chr12 49426676 49426677 + nonframeshift_substitution Complex GC GC AA . pt36_T1_B Somatic p.Q3937_Q3938delinsH* NM_003482 c.11811_11812delinsTT g.49426676_49426677delinsAA . pt36 T1 7.58 0/1 ATP8A1 hg19 chr4 42626582 42626582 + nonsynonymous_SNV SNV C C G . pt36_T1_B Somatic p.A112P NM_006095 c.334G>C g.42626582C>G . pt36 T1 10.23 0/1 APC hg19 chr5 112175639 112175639 + stopgain SNV C C T rs121913332 pt36_T1_B Somatic p.R1450* NM_000038 c.4348C>T g.112175639C>T . pt36 T1 10.58 0/1 TET1 hg19 chr10 70333420 70333420 + nonsynonymous_SNV SNV C C A . pt36_T1_B Somatic p.T442N NM_030625 c.1325C>A g.70333420C>A . pt36 T1 10.76 0/1 KRAS hg19 chr12 25398285 25398285 + nonsynonymous_SNV SNV C C T rs121913530 pt36_T1_B Somatic p.G12S NM_033360 c.34G>A g.25398285C>T . pt36 T1 12.11 0/1 TP53 hg19 chr17 7572945 7572948 + frameshift_deletion Deletion CTTCT CTTCT C . pt36_T1_B Somatic p.E388Gfs*89 NM_000546 c.1161_1164delAGAA g.7572945_7572948delTTCT . pt36 T1 14.19 0/1 AKT1 hg19 chr14 105246551 105246551 + nonsynonymous_SNV SNV C C T rs121434592 pt36_T1_B Somatic p.E17K NM_001014431 c.49G>A g.105246551C>T . pt36 T1 15.82 0/1 SMAD3 hg19 chr15 67479795 67479795 + stopgain SNV C C T . pt36_T1_B Somatic p.R368* NM_005902 c.1102C>T g.67479795C>T . pt36 T1 15.83 0/1 SMAD2 hg19 chr18 45368252 45368252 + nonsynonymous_SNV SNV G G C . pt36_T1_B Somatic p.D450E NM_001003652 c.1350C>G g.45368252G>C . pt36 T1 17.17 0/1 KMT2D hg19 chr12 49426676 49426677 + nonframeshift_substitution Complex GC GC AA . pt36_T2_B Somatic p.Q3937_Q3938delinsH* NM_003482 c.11811_11812delinsTT g.49426676_49426677delinsAA . pt36 T2 9.09 0/1 ATP8A1 hg19 chr4 42626582 42626582 + nonsynonymous_SNV SNV C C G . pt36_T2_B Somatic p.A112P NM_006095 c.334G>C g.42626582C>G . pt36 T2 12.81 0/1 TET1 hg19 chr10 70333420 70333420 + nonsynonymous_SNV SNV C C A . pt36_T2_B Somatic p.T442N NM_030625 c.1325C>A g.70333420C>A . pt36 T2 13.05 0/1 APC hg19 chr5 112175639 112175639 + stopgain SNV C C T rs121913332 pt36_T2_B Somatic p.R1450* NM_000038 c.4348C>T g.112175639C>T . pt36 T2 14.29 0/1 KRAS hg19 chr12 25398285 25398285 + nonsynonymous_SNV SNV C C T rs121913530 pt36_T2_B Somatic p.G12S NM_033360 c.34G>A g.25398285C>T . pt36 T2 17.86 0/1 TP53 hg19 chr17 7572945 7572948 + frameshift_deletion Deletion CTTCT CTTCT C . pt36_T2_B Somatic p.E388Gfs*89 NM_000546 c.1161_1164delAGAA g.7572945_7572948delTTCT . pt36 T2 19.25 0/1 AKT1 hg19 chr14 105246551 105246551 + nonsynonymous_SNV SNV C C T rs121434592 pt36_T2_B Somatic p.E17K NM_001014431 c.49G>A g.105246551C>T . pt36 T2 20.74 0/1 SMAD3 hg19 chr15 67479795 67479795 + stopgain SNV C C T . pt36_T2_B Somatic p.R368* NM_005902 c.1102C>T g.67479795C>T . pt36 T2 22.4 0/1 SMAD2 hg19 chr18 45368252 45368252 + nonsynonymous_SNV SNV G G C . pt36_T2_B Somatic p.D450E NM_001003652 c.1350C>G g.45368252G>C . pt36 T2 22.84 0/1 TP53 hg19 chr17 7577538 7577538 + nonsynonymous_SNV SNV C C T rs11540652 pt37_T1_B Somatic p.R248Q NM_000546 c.743G>A g.7577538C>T . pt37 T1 0.59 0/1 SMAD4 hg19 chr18 48603032 48603032 + stopgain SNV C C T rs377767360 pt37_T1_B Somatic p.R445* NM_005359 c.1333C>T g.48603032C>T . pt37 T1 0.73 0/1 PIK3CA hg19 chr3 178936091 178936091 + nonsynonymous_SNV SNV G G A rs104886003 pt37_T1_B Somatic p.E545K NM_006218 c.1633G>A g.178936091G>A . pt37 T1 0.76 0/1 KRAS hg19 chr12 25398284 25398284 + nonsynonymous_SNV SNV C C A rs121913529 pt37_T1_B Somatic p.G12V NM_033360 c.35G>T g.25398284C>A . pt37 T1 1.01 0/1 APC hg19 chr5 112174877 112174877 + frameshift_deletion Deletion AT AT A . pt37_T1_B Somatic p.S1196Hfs*69 NM_000038 c.3586delT g.112174877delT . pt37 T1 1.32 0/1 HMCN1 hg19 chr1 186120741 186120741 + stopgain SNV C C A . pt38_T1_B Somatic p.S4921* NM_031935 c.14762C>A g.186120741C>A . pt38 T1 11.94 0/1 TP53 hg19 chr17 7577558 7577559 + frameshift_deletion Deletion AGG AGG A . pt38_T1_B Somatic p.S241Lfs*22 NM_000546 c.722_723delCC g.7577558_7577559delGG . pt38 T1 19.86 0/1 APC hg19 chr5 112174484 112174484 + stopgain SNV C C T . pt38_T1_B Somatic p.Q1065* NM_000038 c.3193C>T g.112174484C>T . pt38 T1 20.08 0/1 MSH2 hg19 chr2 47643534 47643534 + stopgain SNV C C T . pt38_T2_B Somatic p.Q348* NM_000251 c.1042C>T g.47643534C>T . pt38 T2 0.36 0/1 FOXP1 hg19 chr3 71021324 71021324 + nonsynonymous_SNV SNV A A G . pt39_T1_B Somatic p.I513T NM_001244810 c.1538T>C g.71021324A>G . pt39 T1 10.86 0/1 FOXA1 hg19 chr14 38061273 38061273 + nonsynonymous_SNV SNV C C G . pt39_T1_B Somatic p.G239A NM_004496 c.716G>C g.38061273C>G . pt39 T1 11.31 0/1 KDR hg19 chr4 55970937 55970937 + nonsynonymous_SNV SNV G G T . pt39_T1_B Somatic p.S620R NM_002253 c.1860C>A g.55970937G>T . pt39 T1 11.59 0/1 RICTOR hg19 chr5 39002703 39002703 + nonsynonymous_SNV SNV T T C . pt39_T1_B Somatic p.Y109C NM_152756 c.326A>G g.39002703T>C . pt39 T1 12.55 0/1 FLT1 hg19 chr13 28896990 28896990 + nonsynonymous_SNV SNV C C T . pt39_T1_B Somatic p.E964K NM_002019 c.2890G>A g.28896990C>T . pt39 T1 22.47 0/1 PTPN11 hg19 chr12 112926888 112926888 + nonsynonymous_SNV SNV G G T . pt39_T1_B Somatic p.G503V NM_002834 c.1508G>T g.112926888G>T . pt39 T1 22.86 0/1 IMPG1 hg19 chr6 76728546 76728546 + nonsynonymous_SNV SNV C C G . pt39_T1_B Somatic p.E232D NM_001563 c.696G>C g.76728546C>G . pt39 T1 24.93 0/1 APC hg19 chr5 112174112 112174112 + stopgain SNV G G T . pt39_T1_B Somatic p.E941* NM_000038 c.2821G>T g.112174112G>T . pt39 T1 25.76 0/1 TP53 hg19 chr17 7578406 7578406 + nonsynonymous_SNV SNV C C T rs28934578 pt39_T1_B Somatic p.R175H NM_000546 c.524G>A g.7578406C>T . pt39 T1 33.95 0/1 APC hg19 chr5 112179687 112179687 + stopgain SNV C C A . pt40_T1_B Somatic p.S2799* NM_000038 c.8396C>A g.112179687C>A . pt40 T1 1.17 0/1 TRIM24 hg19 chr7 138189146 138189146 + stopgain SNV C C A . pt40_T1_B Somatic p.S159* NM_015905 c.476C>A g.138189146C>A . pt40 T1 1.63 0/1 APC hg19 chr5 112175513 112175513 + stopgain SNV G G T . pt40_T1_B Somatic p.E1408* NM_000038 c.4222G>T g.112175513G>T . pt40 T1 23.38 0/1 KRAS hg19 chr12 25398284 25398285 + nonframeshift_substitution Complex CC CC AA . pt40_T1_B Somatic p.G12F NM_033360 c.34_35delinsTT g.25398284_25398285delinsAA . pt40 T1 34.2 0/1 APC hg19 chr5 112173968 112173968 + stopgain SNV G G T . pt40_T1_B Somatic p.E893* NM_000038 c.2677G>T g.112173968G>T . pt40 T1 47.4 0/1 TP53 hg19 chr17 7578208 7578208 + nonsynonymous_SNV SNV T T C . pt40_T1_B Somatic p.H214R NM_000546 c.641A>G g.7578208T>C . pt40 T1 58.67 1/0 SMAD4 hg19 chr18 48593504 48593504 + nonsynonymous_SNV SNV G G T . pt40_T1_B Somatic p.G419W NM_005359 c.1255G>T g.48593504G>T . pt40 T1 59.83 1/0 KRAS hg19 chr12 25398284 25398284 + nonsynonymous_SNV SNV C C A rs121913529 pt40_T2_B Somatic p.G12V NM_033360 c.35G>T g.25398284C>A . pt40 T2 0.4 0/1 TRIM24 hg19 chr7 138189146 138189146 + stopgain SNV C C A . pt40_T2_B Somatic p.S159* NM_015905 c.476C>A g.138189146C>A . pt40 T2 1.03 0/1 APC hg19 chr5 112179687 112179687 + stopgain SNV C C A . pt40_T2_B Somatic p.S2799* NM_000038 c.8396C>A g.112179687C>A . pt40 T2 2.02 0/1 APC hg19 chr5 112175513 112175513 + stopgain SNV G G T . pt40_T2_B Somatic p.E1408* NM_000038 c.4222G>T g.112175513G>T . pt40 T2 23.93 0/1 KRAS hg19 chr12 25398284 25398285 + nonframeshift_substitution Complex CC CC AA . pt40_T2_B Somatic p.G12F NM_033360 c.34_35delinsTT g.25398284_25398285delinsAA . pt40 T2 31.76 0/1 APC hg19 chr5 112173968 112173968 + stopgain SNV G G T . pt40_T2_B Somatic p.E893* NM_000038 c.2677G>T g.112173968G>T . pt40 T2 44.24 0/1 SMAD4 hg19 chr18 48593504 48593504 + nonsynonymous_SNV SNV G G T . pt40_T2_B Somatic p.G419W NM_005359 c.1255G>T g.48593504G>T . pt40 T2 55.45 1/0 TP53 hg19 chr17 7578208 7578208 + nonsynonymous_SNV SNV T T C . pt40_T2_B Somatic p.H214R NM_000546 c.641A>G g.7578208T>C . pt40 T2 59.21 1/0 APC hg19 chr5 112151204 112151204 + stopgain SNV C C T . pt41_T1_B Somatic p.R283* NM_000038 c.847C>T g.112151204C>T . pt41 T1 29.86 0/1 APC hg19 chr5 112175982 112175982 + stopgain SNV T T G . pt41_T1_B Somatic p.L1564* NM_000038 c.4691T>G g.112175982T>G . pt41 T1 37.74 0/1 KRAS hg19 chr12 25380276 25380276 + nonsynonymous_SNV SNV T T A rs121913240 pt41_T1_B Somatic p.Q61L NM_033360 c.182A>T g.25380276T>A . pt41 T1 59.54 1/0 TP53 hg19 chr17 7578538 7578538 + frameshift_insertion Insertion G G GT . pt41_T1_B Somatic p.N131Kfs*18 NM_000546 c.392dupA g.7578539dupT . pt41 T1 59.95 1/0 AMER1 hg19 chrX 63411678 63411678 + stopgain SNV G G A . pt41_T1_B Somatic p.R497* NM_152424 c.1489C>T g.63411678G>A . pt41 T1 81.86 1月1日 APC hg19 chr5 112151204 112151204 + stopgain SNV C C T . pt41_T2_B Somatic p.R283* NM_000038 c.847C>T g.112151204C>T . pt41 T2 13.52 0/1 APC hg19 chr5 112175982 112175982 + stopgain SNV T T G . pt41_T2_B Somatic p.L1564* NM_000038 c.4691T>G g.112175982T>G . pt41 T2 22.1 0/1 TP53 hg19 chr17 7578538 7578538 + frameshift_insertion Insertion G G GT . pt41_T2_B Somatic p.N131Kfs*18 NM_000546 c.392dupA g.7578539dupT . pt41 T2 25.54 0/1 KRAS hg19 chr12 25380276 25380276 + nonsynonymous_SNV SNV T T A rs121913240 pt41_T2_B Somatic p.Q61L NM_033360 c.182A>T g.25380276T>A . pt41 T2 34.92 0/1 AMER1 hg19 chrX 63411678 63411678 + stopgain SNV G G A . pt41_T2_B Somatic p.R497* NM_152424 c.1489C>T g.63411678G>A . pt41 T2 47.56 0/1