Figure 5-Source Data 3,,,,,,,,,
Figure 5C,,,,,,,,,
List of IPA upstream regulators with mapped E18.5 fetal cardiac genes confidently regulated by maternal obesity.,,,,,,,,,
Upstream Regulator,Expr Log Ratio,Molecule Type,Predicted Activation State,Activation z-score,Notes,Bias Term,Bias-corrected z-score,p-value of overlap,Target molecules in dataset
elaidic acid, ,chemical - endogenous mammalian,Inhibited,-3.036, ,0.135,-3.571,7.48E-15,"ACACA,CYP51A1,DGAT2,DHCR24,FABP5,FADS1,FASN,FDPS,HMGCS1,HSD17B12,IDI1,LDLR,MVK,NSDHL,PCYT2,SCD"
SCAP,-0.068,other,Inhibited,-3.512, ,0.139,-4.001,2.97E-14,"ACACA,CYP51A1,FABP5,FADS2,FASN,FDPS,HMGCS1,IDI1,INSIG1,LDLR,Mt2,MVK,NSDHL,SCD,Scd2"
POR,0.02,enzyme,Activated,2.897, ,-0.053,3.08,2.39E-13,"Acot1,BDH1,CPT1A,CPT2,CYP51A1,DHCR24,FADS2,FDPS,HMGCS1,HSD17B12,IDI1,INSIG1,LDLR,MVK,NSDHL,SCD,Scd2,SDC4,TUBB2B"
SREBF2,-0.088,transcription regulator,Inhibited,-2.826, ,0.108,-3.22,2.44E-13,"ACACA,CAMK1D,CYP51A1,FABP5,FADS2,FASN,FDPS,HMGCS1,IDI1,INSIG1,LDLR,MVK,NSDHL,SCD"
PPARA,-0.078,ligand-dependent nuclear receptor,Activated,2.09, ,0.04,1.907,5.11E-13,"ACACA,Acot1,ACOT2,ALDH9A1,ANGPTL4,ANXA2,CPT1A,CPT2,CYP51A1,ECH1,FABP5,FADS1,FADS2,FASN,FDPS,FGB,FGG,H1-2,HMGCS1,IDI1,IGFBP5,INSIG1,MVK,NSDHL,PLIN5,SCD,SELENBP1,SLC25A20"
INSIG1,-0.544,other,Activated,3.358, ,-0.138,3.877,6.77E-13,"ACACA,CYP51A1,DHCR24,FABP5,FADS1,FADS2,FASN,FDPS,HMGCS1,IDI1,LDLR,MVK,PCYT2,SCD,Scd2"
MFSD2A, ,transporter,Activated,3, ,-0.131,3.393,1.12E-12,"CYP51A1,FADS1,FADS2,FASN,IDI1,INSIG1,LDLR,SCD,Scd2"
methylprednisolone, ,chemical drug, ,0.946, ,0.028,0.808,1.70E-11,"AGO1,ANXA2,ANXA3,BDH1,C1QBP,CAMK1D,CCN2,CTSV,DDIT4,ECE1,EDNRB,FABP5,HSD17B12,IGF2R,INSIG1,JUN,LDLR,MMP11,MVK,NSDHL,PCYT2,PLAT,PSAT1,SDC4,SLC16A6,TFRC,TIMP3,YBX3"
lysophosphatidylcholine, ,chemical - other,Inhibited,-2.891, ,0.108,-3.263,2.32E-11,"CYP51A1,FABP5,FADS2,FASN,HMGCS1,INSIG1,JUN,LDLR,MVK,NSDHL,SCD,TNFRSF9"
FOXO4,0.1,transcription regulator, ,-1.103, ,0.003,-1.113,2.64E-11,"ACACA,ANXA3,BNIP3,CCN2,CYP51A1,DHCR24,EDNRB,FABP5,FASN,FLNB,HMGCS1,IDI1,SCD,Scd2"
TGFB1,-0.015,growth factor, ,1.037, ,0.046,0.748,2.06E-10,"Acot1,ADM,ANGPTL4,ANXA2,BDH1,BNIP3L,CCN1,CCN2,CDT1,CLU,CORIN,DDIT4,DKK3,ECE1,EDNRB,FABP5,FASN,FGB,FGF12,FGG,FLNB,FXYD6,GAS1,HEY1,IDI1,IGFBP5,IL33,ITGA6,JUN,LDLR,LOXL2,MAF,MAPK3,MMP11,NFATC2,PECAM1,PLAT,PMEPA1,PROM1,PSAT1,PXN,SCD,SDC4,SELENBP1,SLN,SNTB2,SPC25,STAT5B,TENM4,TFRC,TIMP3,TUBB2A,VWF"
FOXO1,0.031,transcription regulator, ,-0.5, ,0.07,-0.781,5.50E-10,"ACACA,ANGPTL4,ANXA3,BNIP3,CASP6,CCN2,CPT2,CTSV,DDIT4,DNAJC19,EDNRB,FABP5,FASN,FDPS,FGF18,FLNB,JUN,MRPS22,RIPOR2,SCD,SLC25A20,SPC25,STAT5B,TNFRSF9"
ATP7B,0.184,transporter, ,-1.667, ,0.011,-1.7,6.56E-10,"CYP51A1,FABP5,FASN,FDPS,H1-2,HMGCS1,IDI1,LDLR,Mt2"
l-asparaginase, ,biologic drug,Activated,3.051, ,-0.111,3.453,6.90E-10,"CENPL,CYP51A1,FASN,FDPS,HMGCS1,IDI1,INSIG1,KIF20B,LDLR,NSDHL,PSAT1,SPC25,UBE2C"
TP53,-0.03,transcription regulator,Activated,2.115, ,0.018,2.009,1.01E-09,"AKAP12,ALDH9A1,ANXA2,ANXA3,BNIP3,CASP6,CCN1,CCN2,CDT1,CLU,Cox5b,CPT1A,CPT2,CTSF,CYP51A1,DDIT4,DHCR24,DKK3,ECH1,FABP5,FASN,FDPS,FGF13,GAS1,GPM6A,HDC,HMGCS1,IGFBP5,JUN,LDLR,MAPK3,MRPL12,Mt2,MVK,NDRG1,NDUFS6,PECAM1,PMEPA1,PPFIBP1,PPM1F,PROM1,RAD23A,RANGAP1,SCD,SGTB,SHC1,SPC25,TCAP,TFRC,TIMP3,TNFRSF9,UBE2C,VEGFB"
EPAS1,0.097,transcription regulator, ,1.406, ,0.112,1.011,1.23E-09,"ACACA,ADM,AKAP12,ANGPTL4,BNIP3,CCN1,CCN2,CYP51A1,DGAT2,FASN,H1-2,HMGCS1,IGFBP5,LDLR,LOXL2,NDRG1,SLC16A4"
metribolone, ,chemical reagent, ,-0.171, ,0.109,-0.687,1.41E-09,"ACACA,AKAP12,ALDH9A1,CLU,CPT2,DHCR24,ECH1,FASN,FDPS,GRIP1,HMGCS1,IDI1,IGFBP5,ITGA6,KMT5A,LDLR,MAF,MRPS22,NDRG1,NDUFS8,NSDHL,PMEPA1,RAD23A"
pirinixic acid, ,chemical toxicant, ,1.417, ,0.09,1.035,1.60E-09,"ACACA,Acot1,ACOT2,ALDH9A1,ANGPTL4,ANXA2,BNIP3,CLU,CPT1A,CPT2,ECH1,FABP5,FADS1,FADS2,FASN,FGB,H1-2,HMGCS1,INSIG1,LDLR,PLIN5,SCD,SLC25A20"
cholesterol, ,chemical - endogenous mammalian, ,1.934, ,0.048,1.748,1.71E-09,"ACACA,Acot1,CAMK1D,CPT1A,FABP5,FADS1,FASN,FDPS,HMGCS1,IDI1,INSIG1,LDLR,NSDHL,PCYT2,PSAT1,SCD,TIMP3"
dexamethasone, ,chemical drug, ,-0.23, ,0.019,-0.36,2.20E-09,"ACACA,ADM,AKAP12,ANGPTL4,ANXA3,BNIP3,CASP6,CCN1,CCN2,CLU,COL4A5,Cox5b,CRH,CTNNAL1,CTSV,CYP51A1,DDIT4,DGAT2,DHCR24,DUSP10,ECT2,EDNRB,EPB41,FABP5,FASN,FGB,FGG,FLNB,GAS1,HEY1,IGFBP5,IL33,IRF2BP2,ITPR3,JUN,KLF3,LDLR,LY75,MAF,MAPK3,MSLN,Mt2,MVK,NAGA,NAT8B,NTS,PEX11G,PLAT,SCD,Scd2,SELENBP1,SHC1,SLC25A34,TFRC,TIMP3,TNFRSF9,UBE2C"
beta-estradiol, ,chemical - endogenous mammalian,Inhibited,-2.123, ,0.041,-2.404,2.82E-09,"Acot1,ADM,AKAP12,ANXA3,BNIP3L,C1QBP,CCN1,CCN2,CDT1,CLU,COL4A5,CPT1A,CYP51A1,DDIT4,DHCR24,DUSP10,ECH1,FABP5,FADS1,FASN,FGB,FLNB,GRIP1,HEY1,HMGCS1,HSD17B12,HSPA2,IGF2R,IGFBP5,INSIG1,JUN,LDLR,LMCD1,MAF,MAPK3,MGARP,MVK,NDRG1,NSDHL,NTS,Pcp4l1,PLAT,PRKCH,PROM1,PSAT1,PXDN,PXN,RYR3,SDC4,SELENBP1,SHC1,SPRED2,TIMP3,UBE2C,VAMP1,VWF"
Ins1, ,other, ,-1.413, ,0.056,-1.641,3.05E-09,"ACACA,Acot1,ANGPTL4,BDH1,DGAT2,FADS1,FADS2,FASN,HMGCS1,IGFBP5,ITGA6,JUN,LDLR,MAPK3,Marcks,PLAT,SCD,Scd2,TIMP3"
nitric oxide, ,chemical - endogenous mammalian, ,1.226, ,0.053,1.07,4.01E-09,"BNIP3,CCN2,CRH,ECE1,HEY1,JUN,Mt2,NDRG1,NID1,PECAM1,SLC16A4,TFRC,TIMP3,UBE2C"
HRAS,-0.143,enzyme, ,-1.405, ,0.043,-1.559,4.15E-09,"ACACA,ADM,ANXA2,ANXA3,BNIP3,CCN1,CCN2,CLU,CPT1A,CTSV,FASN,HDC,HEY1,IGFBP5,ITGA6,JUN,KLF3,LBH,MAPK3,MRPL12,NID1,PMEPA1,PXN,SCD,Scd2,SLN,TENM4,TIMP3"
Tgf beta, ,group, ,0.234, ,0.062,-0.013,7.40E-09,"ANGPTL4,CCN1,CCN2,CLU,FGG,HEY1,IGFBP5,ITGA6,JUN,LMCD1,MAF,MMP11,PLAT,PMEPA1,PROM1,RYR3,TFRC,TIMP3"
ADRB, ,group,Activated,2.496, ,-0.047,2.667,8.42E-09,"ANGPTL4,BNIP3,BNIP3L,CASP6,CYP51A1,DDIT4,FDPS,HMGCS1,INSIG1,JUN,LBH,NSDHL,PCYT2"
Am 580, ,chemical toxicant,Activated,2.328, ,0.021,2.266,8.76E-09,"ADM,CPT1A,CYP51A1,FASN,HMGCS1,ITGA6,MVK,PLAT,SCD"
(-)-norephedrine, ,chemical drug,Inhibited,-2.449, ,0.144,-2.802,8.93E-09,"CYP51A1,FDPS,HMGCS1,IDI1,LDLR,MVK"
INSIG2,0.052,other,Activated,2.391, ,-0.144,2.735,8.93E-09,"ACACA,FASN,FDPS,INSIG1,LDLR,SCD"
TRIB1,0.166,kinase,Activated,2.216, ,-0.036,2.295,9.57E-09,"ACACA,CPT1A,CPT2,FASN,SCD"
fenofibrate, ,chemical drug, ,1.456, ,0.041,1.295,1.10E-08,"Acot1,ACOT2,ANGPTL4,CLU,CPT1A,CPT2,DGAT2,ECH1,FADS2,FASN,FGB,FGG,JUN,LDLR,SCD,SLC25A20,VEGFB"
PPARG,0.023,ligand-dependent nuclear receptor, ,-0.551, ,0.042,-0.73,1.15E-08,"ACACA,ALDH9A1,ANGPTL4,BDH1,CCN2,CORIN,CPT1A,CPT2,DGAT2,FABP5,FASN,FDPS,IGFBP5,IL33,INSIG1,JUN,LDLR,NDRG1,PECAM1,PLIN5,SCD,SLC25A20,STAT5B"
deferoxamine, ,chemical drug, ,0.907, ,0.073,0.633,1.20E-08,"ADM,ANGPTL4,ANXA2,BNIP3,DUSP10,FASN,FGF18,IGFBP5,JUN,LY75,NDRG1,NFATC2,PLAT,PROM1,TFRC"
F2, ,peptidase, ,1.008, ,0.13,0.49,1.22E-08,"ANGPTL4,CCN1,CCN2,CLU,DKK3,ECE1,EDNRB,EPB41,IGFBP5,JUN,LBH,LMCD1,LOXL2,MAPK3,PLAT,SDC4,VWF"
FOXO3,0.122,transcription regulator, ,1.324, ,0.03,1.21,1.30E-08,"Acot1,ANXA3,BNIP3,BNIP3L,CCN1,CCN2,CDT1,CPT1A,CTSV,DDIT4,EDNRB,FABP5,FASN,FLNB,Mt2,NDRG1,PECAM1,TAL1,UBE2C"
TO-901317, ,chemical reagent, ,-1.836, ,0.043,-1.986,1.39E-08,"ACACA,Acot1,ADM,CPT1A,FABP5,FADS1,FADS2,FASN,FDPS,HSD17B12,ITGA6,LDLR,Mt2,SCD,Scd2,TIMP3"
SH3TC2,0.075,other,Inhibited,-2.646, ,0.124,-2.974,2.70E-08,"CYP51A1,DHCR24,FDPS,HMGCS1,IDI1,MVK,NSDHL"
SREBF1,-0.248,transcription regulator,Inhibited,-2.688, ,0.102,-3.085,3.29E-08,"ACACA,CAMK1D,CYP51A1,FABP5,FADS1,FADS2,FASN,FDPS,HMGCS1,IDI1,INSIG1,LDLR,NSDHL,SCD,Scd2,TNNI2"
AGN194204, ,chemical drug, ,0.781, ,0.086,0.525,4.73E-08,"Acot1,ANGPTL4,ANXA2,BNIP3L,CPT1A,CYP51A1,EPB41,FDPS,H1-2,IDI1,IL33,NSDHL,SCD,Scd2,STAT5B"
KLF15,0.022,transcription regulator, ,1.689, ,0.074,1.488,6.00E-08,"Acot1,CCN2,CPT2,DGAT2,FABP5,FASN,SCD,SLC25A20"
ezetimibe, ,chemical drug,Inhibited,-2.431, ,0.083,-2.633,1.25E-07,"CYP51A1,FDPS,HMGCS1,IDI1,LDLR,MVK"
INSR,0.08,kinase, ,-1.363, ,0.114,-1.769,1.67E-07,"ACOT2,CASP6,CCN2,Cox5b,CPT2,CTSV,CYP51A1,FASN,FDPS,GAS1,HMGCS1,IDI1,IGF2R,MMP11,MVK,NDRG1,NSDHL,SCD,SLC25A20"
PPARGC1A,0.024,transcription regulator, ,0.505, ,0.033,0.37,1.68E-07,"ACACA,BDH1,BNIP3,CCN2,Cox5b,CPT1A,FASN,FDPS,IGFBP5,INSIG1,LDLR,NDUFS8,NSDHL,PLIN5,SCD,Sik1,SLC25A20,TIMP3"
thioacetamide, ,chemical toxicant, ,1.501, ,0.123,1.231,2.07E-07,"ACOT2,AKAP12,ANXA2,CCN2,CLU,CTSF,CYGB,DKK3,EDNRB,FGB,FXYD6,JUN,PECAM1,PROM1,Scd2"
MBTPS1,0.009,peptidase,Inhibited,-2.236, ,0.122,-2.509,2.10E-07,"ACACA,FASN,FDPS,LDLR,SCD"
HTT,-0.07,transcription regulator,Activated,2.236, ,0.03,2.17,2.68E-07,"ACOT2,AKAP12,CCN2,CYP51A1,DKK3,EDNRB,FASN,FDPS,FXYD6,HMGCS1,IGFBP5,JUN,LDLR,Marcks,NDUFA11,NFIC,NTS,PROM1,SCAMP5,Scd2,SGTB,Sik1,TFRC,TIMP3,TNNI2,VAMP1"
arachidonic acid, ,chemical - endogenous mammalian, ,0.468, ,0.031,0.373,3.15E-07,"ACACA,CLU,FADS1,FADS2,FASN,JUN,LDLR,PECAM1,SCD,TNFRSF9"
chloropromazine, ,chemical drug, , , , , ,4.12E-07,"FADS2,FDPS,HMGCS1,IDI1,LDLR,MVK,SCD"
isoquercitrin, ,chemical drug,Inhibited,-2.236, ,0.125,-2.515,4.81E-07,"CYP51A1,FASN,FDPS,INSIG1,LDLR"
GLP-1 (7-36) amide, ,biologic drug, ,1.982, ,-0.062,2.105,5.39E-07,"ACACA,FASN,ITPR3,SCD"
raloxifene, ,chemical drug, ,-1.155, ,0,-1.155,5.89E-07,"ANXA3,CLU,DDIT4,ECH1,FLNB,JUN,LDLR,NDRG1,PXDN,SELENBP1,TFRC,TIMP3"
ELOVL5,0.049,enzyme, ,1.685, ,-0.093,1.912,5.94E-07,"ACACA,Acot1,FADS1,FADS2,FASN,SCD"
mibolerone, ,chemical drug,Inhibited,-3.13, ,0.049,-3.285,6.12E-07,"ACACA,CLU,CYP51A1,FASN,FDPS,HMGCS1,JUN,LDLR,PRKCH,Scd2,TIMP3"
CREB1,-0.001,transcription regulator, ,-0.517, ,0.049,-0.7,6.49E-07,"ADM,BNIP3,CAMK1D,CCDC85A,CCN1,CPT1A,CRH,CYP51A1,FASN,FGF13,HMGCS1,IDI1,IGSF9B,JUN,LDLR,MVK,NEURL1B,PLAT,RIPOR2,SCD,Sik1,TFRC"
methotrexate, ,chemical drug, ,0.632, ,0.021,0.567,7.84E-07,"BNIP3L,CPT1A,CTSV,DGAT2,DUSP10,ECH1,FADS1,FASN,HMGCS1,IGFBP5,SCD,STAT5B,TEF,TIMP3"
atorvastatin, ,chemical drug,Inhibited,-2.88, ,-0.023,-2.801,7.91E-07,"CCN1,CCN2,CYP51A1,DHCR24,FDPS,HMGCS1,IDI1,JUN,LDLR,MAPK3,MVK,NSDHL,PLAT"
tretinoin, ,chemical - endogenous mammalian,Activated,2.253, ,0.048,1.973,8.53E-07,"ADM,AGO1,AKAP12,ALDH9A1,ANGPTL4,ANXA2,BNIP3,BNIP3L,CASP6,CCN1,CCN2,CHRM2,COL4A5,CPT1A,CRH,DKK3,ECE1,FABP5,FASN,FGF12,FGG,HEY1,HSPA2,IGFBP5,ITGA6,JUN,LOXL2,Marcks,MMP11,MSLN,NDRG1,PLAT,PRKCH,PROM1,SCD,SLC25A20,TAL1,TFRC,UBE2C,UBE2L6,VWF"
CTNNB1,0.038,transcription regulator, ,-0.332, ,0.089,-0.679,1.01E-06,"ACACA,CCN1,CCN2,CLU,COL4A5,CPT1A,CPT2,CTSF,CYP51A1,DGAT2,FASN,FGF18,HMGCS1,IDI1,IGFBP5,ITGA6,JUN,LBH,MAN2B1,Nes,PECAM1,PROM1,RAD23A,SALL1,SCD,SLC16A6,STAT5B,TIMP3,TUBB2B"
isobutylmethylxanthine, ,chemical toxicant, ,-0.426, ,0.073,-0.643,1.21E-06,"ANGPTL4,CCN2,Cox5b,CRH,DGAT2,GRIP1,JUN,MAPK3,Mt2,PLAT,SCD,Scd2,TIMP3"
arsenic trioxide, ,chemical drug,Activated,2.788, ,0.014,2.737,1.25E-06,"ARID3A,BNIP3,BNIP3L,CYP51A1,DHCR24,ECT2,FADS1,FASN,FDPS,HMGCS1,HSPA2,IDI1,MAF,NDUFA11,SCD,TFRC"
IFT88,0.128,other, ,1.741, ,-0.029,1.811,1.38E-06,"CYP51A1,FDPS,HMGCS1,IDI1,NSDHL,TIMP3"
rosuvastatin, ,chemical drug,Inhibited,-2.433, ,0.027,-2.498,1.38E-06,"CYP51A1,FDPS,HMGCS1,IDI1,LDLR,MVK"
RETN, ,other, ,-0.284, ,0.085,-0.502,1.41E-06,"ACACA,CCN2,FABP5,FASN,LDLR,PLAT,SCD"
bezafibrate, ,chemical drug,Activated,2.018, ,0.101,1.743,1.42E-06,"Acot1,ACOT2,ANGPTL4,BNIP3,ECH1,FASN,FGB,INSIG1,SCD"
GNAQ,0.081,enzyme, ,0, ,0.117,-0.232,1.48E-06,"ADM,ANXA3,BNIP3,BNIP3L,CCN2,CTSV,INSIG1,LMCD1,PLAT,SELENBP1"
linoleic acid, ,chemical - endogenous mammalian, ,0.657, ,0.052,0.512,1.51E-06,"ANGPTL4,CLU,CPT1A,FASN,LDLR,PECAM1,PLIN5,SCD"
ERBB2,-0.023,kinase, ,-1.296, ,0.078,-1.631,1.70E-06,"ANGPTL4,ANXA2,BNIP3,CCN2,CDT1,CLU,CPT2,CYP51A1,FASN,HEPH,HEY1,IDI1,IGF2R,IGFBP5,ITGA6,JUN,MAF,Marcks,MMP11,NDRG1,NID1,PLAT,PMEPA1,PROM1,TIMP3,UBE2C,VWF"
SP600125, ,chemical - kinase inhibitor,Activated,2.414, ,-0.042,2.573,1.71E-06,"ADM,BDH1,CCN1,CCN2,CYGB,CYP51A1,DDIT4,FABP5,FASN,ITGA6,JUN,LDLR,SCD,Scd2,SLC16A6"
LEP, ,growth factor, ,1.757, ,0.057,1.54,1.72E-06,"ACACA,ANGPTL4,CASP6,CCN1,CPT1A,CRH,CTSV,ECH1,FADS2,FASN,JUN,LDLR,NTS,PECAM1,PLAT,SCD,Scd2,STEAP4,TIMP3"
RPTOR,-0.037,other,Inhibited,-2.985, ,0.089,-3.25,2.17E-06,"CYP51A1,DHCR24,FDPS,HMGCS1,IDI1,JUN,LY75,MVK,NSDHL"
HIF1A,-0.047,transcription regulator,Activated,2.172, ,0.098,1.788,2.18E-06,"ADM,AKAP12,ANGPTL4,BNIP3,BNIP3L,CCN1,CCN2,DDIT4,EDNRB,H1-2,IGFBP5,JUN,LOXL2,NDRG1,PROM1,SDC4,SLC16A4,TFRC"
AGT, ,growth factor, ,-1.56, ,0.071,-1.852,2.34E-06,"ADM,ANXA3,CCN2,Cox5b,EDNRB,FASN,FGF13,HEY1,HMGCS1,IDI1,IGFBP5,JUN,LDLR,NDRG1,PECAM1,PPFIBP1,SHC1,SLC13A1,TFRC"
TFAM,-0.012,transcription regulator, ,1.342, ,0.072,1.181,2.37E-06,"CPT2,ECH1,FABP5,mt-Atp8,SLC25A20"
FOS,-0.197,transcription regulator, ,-0.269, ,0.044,-0.413,2.74E-06,"ACACA,ARID3A,CCN2,CLU,CRH,CTSV,FASN,GAS1,IGFBP5,ITGA6,JUN,MSLN,Mt2,NSDHL,NTS,PCYT2,PLAT,PMEPA1,SCD,SELENBP1,TAL1"
PML,-0.02,transcription regulator, ,1.85, ,0.005,1.835,3.06E-06,"ACACA,CPT1A,FASN,HMGCS1,IDI1,LDLR,MAF,NDRG1,PRKCH,SCD,SLC25A20"
nitrofurantoin, ,chemical drug, ,1.035, ,0.018,0.974,3.06E-06,"ANXA2,CASP6,CLU,CPT1A,CTSV,FGB,HMGCS1,MAPK3,PLAT,SELENBP1,TIMP3"
ethanol, ,chemical - endogenous mammalian, ,0.531, ,0.043,0.367,3.11E-06,"ACACA,ADM,CCN2,CLU,CPT1A,CRH,EDNRB,FASN,GPM6A,HEY1,JUN,LDLR,NSDHL,PLAT,SCD,Sik1,STAT5B"
KDM3A,0.141,transcription regulator, ,0.896, ,0.128,0.584,3.37E-06,"ADM,ARHGEF28,CCN1,CCN2,IL33,LOXL2"
EGF,0.001,growth factor, ,0.533, ,0.091,0.161,3.77E-06,"ACOT2,ANGPTL4,CCN1,CCN2,CLU,FASN,GAS1,HMGCS1,IDI1,IGFBP5,JUN,MAPK3,PLAT,PRKCH,PROM1,SCD,Scd2,SHC1,TIMP3,TNFRSF9"
tamoxifen, ,chemical drug, ,1.361, ,0.007,1.336,4.08E-06,"ACACA,ADM,CCN1,CLU,FADS1,FADS2,FASN,HMGCS1,JUN,LDLR,LOXL2,SALL1,SCD,Scd2,SHC1"
KIF3A,0.087,enzyme,Activated,2.207, ,-0.093,2.413,5.01E-06,"CYP51A1,FDPS,HMGCS1,IDI1,NSDHL"
clozapine, ,chemical drug, ,-1.298, ,0.084,-1.516,5.55E-06,"ACACA,FASN,FDPS,HMGCS1,LDLR,NTS,SCD"
CCDC3,0.067,other, , , , , ,5.63E-06,"ACACA,DGAT2,FASN"
PDE8A,0.121,enzyme, , , , , ,5.63E-06,"CYP51A1,FDPS,LDLR"
YAP/TAZ, ,group, , , , , ,5.63E-06,"CCN1,CCN2,PSAT1"
lovastatin, ,chemical drug, ,-1.096, ,0.055,-1.241,6.86E-06,"CCN2,FASN,FDPS,HMGCS1,LDLR,MVK,PLAT,SDC4,VWF,Xlr3c (includes others)"
Hif1, ,complex,Activated,2.621, ,0.13,2.281,6.91E-06,"ADM,BNIP3,BNIP3L,DDIT4,LOXL2,TFRC,TNFRSF9"
trans-hydroxytamoxifen, ,chemical drug,Inhibited,-2.724, ,-0.023,-2.648,7.04E-06,"ADM,ANXA3,CLU,COL4A5,DDIT4,ECH1,LOXL2,NDRG1,PXDN,SELENBP1,VEGFB"
PPARD,-0.431,ligand-dependent nuclear receptor, ,-0.496, ,0.045,-0.651,7.13E-06,"ACACA,ALDH9A1,ANGPTL4,BDH1,CPT1A,CPT2,ECH1,FASN,MAPK3,Pcp4l1,PLAT,SCD,SLC25A20"
CDN1163, ,chemical reagent, ,1, ,-0.096,1.192,7.29E-06,"ACACA,DGAT2,FASN,SCD"
CLOCK,-0.04,transcription regulator, ,-0.447, ,-0.014,-0.416,8.42E-06,"ANGPTL4,ARHGEF28,C1QBP,CCN2,CYP51A1,FASN,GALNT11,IGFBP5,PIP4K2C,RAD23A,RANGAP1,SCD,TEF"
oleic acid, ,chemical - endogenous mammalian, ,-0.557, ,0.039,-0.672,8.43E-06,"ACACA,ANGPTL4,CLU,DGAT2,FASN,LDLR,Mt2,PLIN5,SCD"
25-hydroxycholesterol, ,chemical reagent, ,1.707, ,0.025,1.648,8.53E-06,"FASN,FDPS,HMGCS1,INSIG1,JUN,LDLR,SCD"
troglitazone, ,chemical drug,Activated,2.449, ,0.013,2.402,9.18E-06,"Acot1,ACOT2,ANGPTL4,ANXA2,CPT2,CTNNAL1,DGAT2,ECH1,ECT2,FABP5,FADS2,FASN,ITGA6,JUN,NDRG1,SCD"
lipopolysaccharide, ,chemical drug, ,1.578, ,0.07,1.162,1.04E-05,"Acot1,ADM,ANGPTL4,ANXA3,CCN1,CCN2,CRH,CTSV,DDIT4,DDN,DHCR24,DKK3,FABP5,FASN,FGB,GAS1,GPM6A,HDC,HEY1,IGFBP5,IL33,INSIG1,JUN,MAF,Marcks,Mt2,NID1,NTS,PECAM1,PLAT,PMEPA1,SALL1,Scd2,SDC4,SLFN13,SNTB2,STEAP4,TCAP,TENT5C,TFRC,TIMP3,TNFRSF9,VWF,YBX3"
SRF,0.04,transcription regulator, ,-1.992, ,0.059,-2.109,1.07E-05,"AKAP12,CCN2,CORIN,EXTL2,FGF12,GPM6A,ITGA6,JUN,LBH,LDLR,LMCD1,NFATC2,Pcp4l1,TAL1,TCAP"
Map3k7,0.021,kinase, ,0.64, ,0.104,0.387,1.15E-05,"FASN,GAS1,JUN,MVK,NFATC2,PROM1,SCD"
CCNC,-0.069,other, ,-1.432, ,0.123,-1.704,1.16E-05,"ACACA,Cox5b,CPT2,FASN,SCD"
sterol, ,chemical - endogenous mammalian, ,1.505, ,-0.075,1.672,1.40E-05,"ACACA,FASN,FDPS,LDLR,Scd2"
FGF21, ,growth factor, ,-0.802, ,0.063,-0.954,1.42E-05,"ACACA,BDH1,CPT1A,DGAT2,FASN,LDLR"
SB 216763, ,chemical toxicant,Inhibited,-2.416, ,0.103,-2.665,1.42E-05,"ACACA,CCN1,CCN2,FASN,FGF18,SCD"
gemfibrozil, ,chemical drug, ,1.492, ,0.067,1.317,1.54E-05,"ACOT2,CPT1A,CPT2,ECH1,FGB,LDLR,SCD"
eicosapentenoic acid, ,chemical drug, ,1, ,-0.021,1.059,1.54E-05,"ANGPTL4,ECH1,FADS1,FADS2,JUN,LDLR,PROM1,SLC25A20"
clofibrate, ,chemical drug,Activated,2.042, ,0.071,1.844,1.66E-05,"Acot1,ACOT2,CPT1A,CPT2,ECH1,LDLR,Mt2,SCD"
PPARGC1B,-0.139,transcription regulator,Inhibited,-2.577, ,0.114,-2.872,1.69E-05,"ACACA,Cox5b,DHCR24,FASN,FDPS,MVK,SCD"
CG, ,complex, ,1.053, ,0.094,0.705,1.88E-05,"ADM,CLU,CTSV,FABP5,GAS1,IL33,JUN,LDLR,MAF,MAPK3,MVK,PECAM1,PLAT,SDC4,TENM4"
GCK, ,kinase,Inhibited,-2, ,-0.017,-1.965,1.99E-05,"CPT1A,CPT2,FASN,SCD,Scd2"
LPIN1,-0.008,phosphatase, ,-1.96, ,0.048,-2.054,1.99E-05,"ACACA,CPT1A,FASN,FDPS,SCD"
IGF1R,0.042,transmembrane receptor, ,0.994, ,0.095,0.717,2.08E-05,"ANXA3,CLU,Cox5b,CPT2,FASN,IGF2R,IGFBP5,PLAT,PROM1,Scd2,SDC4,SLC25A20,TIMP3"
mifepristone, ,chemical drug, ,-1.957, ,-0.03,-1.844,2.20E-05,"Acot1,ADM,CCN2,CLU,CTSF,DDIT4,DKK3,EDNRB,HDC,JUN,LDLR,NDRG1,PLAT,TIMP3"
D-glucose, ,chemical - endogenous mammalian,Inhibited,-2.079, ,0.044,-2.254,2.29E-05,"ACACA,ANXA3,CCN2,CDT1,CLU,CPT2,CTSV,DDIT4,FABP5,FASN,ITPR3,JUN,LDLR,Mt2,NTS,POPDC2,SCD,Scd2,SHC1,SLC16A4,TFRC"
GW501516, ,chemical drug, ,1.964, ,0.097,1.773,2.38E-05,"Acot1,ANGPTL4,CPT1A,ECH1,FASN,IGFBP5,PLAT,SCD"
STAT5B,0.205,transcription regulator, ,0, ,0.016,-0.054,2.41E-05,"Acot1,CASP6,CORIN,DGAT2,MAF,MYBPHL,MYL7,Pcp4l1,PROM1,SCD,SLN,STAT5B,TCAP"
OSM, ,cytokine, ,0.767, ,0.053,0.542,2.42E-05,"ACOT2,ANXA2,ANXA3,BMP10,CTSV,DHCR24,FASN,FGB,HSPA2,IL33,JUN,LDLR,Mt2,RAD23A,SLC16A6,TAL1,TECR,TIMP3,UBE2L6"
Gm35986, ,other, , , , , ,2.77E-05,"HMGCS1,IDI1,MVK"
OBP2B, ,transporter, , , , , ,2.77E-05,"CPT1A,FASN,SCD"
ghrelin, ,biologic drug, , , , , ,2.77E-05,"ACACA,FASN,SCD"
PDGF BB, ,complex, ,-1.618, ,0.087,-1.936,2.79E-05,"ADM,AKAP12,CCN1,CCN2,EDNRB,FASN,HMGCS1,JUN,LDLR,Mt2,PLAT,RYR3,SCD,Scd2"
APP,0.121,other, ,0.278, ,0.051,0.122,2.86E-05,"C1QBP,CCN2,CLU,CTSV,ECH1,HEY1,IGF2R,IGFBP5,ITGA6,ITPR3,JUN,KCNA4,LDLR,MAF,NDUFS6,NDUFS8,Nes,Pcp4l1,PLAT,RYR3,SDC4,SHC1,SLFN13,TUBB2A,TUBB2B,VEGFB"
AR, ,ligand-dependent nuclear receptor, ,1.729, ,0.086,1.439,2.94E-05,"ADM,CDT1,CORIN,CTSO,DDIT4,DHCR24,EDNRB,EXTL2,FABP5,IGFBP5,ITGA6,Marcks,NDRG1,PLAT,PMEPA1,Sik1,TIMP3,UBE2C"
docosahexaenoic acid, ,chemical drug, ,1.782, ,-0.052,1.936,2.98E-05,"ACACA,CCN2,CPT1A,FADS1,FADS2,FASN,LDLR,LOXL2,PLAT,SCD"
WNT3A, ,cytokine,Inhibited,-2.188, ,0.074,-2.448,2.99E-05,"CCN1,CCN2,CPT2,DDIT4,FGF18,GAS1,IGFBP5,JUN,LBH,Nes,PMEPA1,SDC4,TIMP3"
rosiglitazone, ,chemical drug, ,1.213, ,0.046,1.032,3.01E-05,"ANGPTL4,CCN2,Cox5b,CPT1A,CPT2,DGAT2,ECH1,FABP5,FASN,FGB,FGF13,IGFBP5,INSIG1,PECAM1,PLIN5,SCD,SLC25A20"
fatty acid, ,chemical - endogenous mammalian, ,-0.625, ,0.109,-0.863,3.13E-05,"ACACA,CCN1,FADS1,FADS2,FASN,LDLR,PLIN5,SCD"
TNF, ,cytokine, ,-0.553, ,0.05,-0.858,3.27E-05,"ACACA,ADM,AKAP12,ANGPTL4,CASP6,CCN1,CCN2,CLU,CPT1A,CPT2,CRH,CTSF,DUSP10,ECH1,EDNRB,FABP5,FADS1,FASN,FDPS,FGF18,FGG,HDC,IGFBP5,IL33,INSIG1,ITGA6,JUN,LDLR,MSLN,Mt2,NFATC2,NID1,PECAM1,PLAT,SCD,SDC4,STEAP4,TBC1D8,TFRC,TIMP3,TNFRSF9"
triptolide, ,chemical drug, ,-1.667, ,-0.109,-1.34,3.29E-05,"ADM,AKAP12,EDNRB,FGF18,HEY1,ITGA6,JUN,MMP11,PECAM1"
simvastatin, ,chemical drug, ,0.43, ,-0.033,0.501,3.37E-05,"ANXA3,CCN1,CCN2,FADS1,FADS2,H1-2,LDLR,PLAT,SDC4,VWF,Xlr3c (includes others)"
FGF10, ,growth factor, ,0.243, ,0.138,-0.093,3.54E-05,"ANXA2,ANXA3,CYP51A1,LDLR,SCD,TIMP3"
valproic acid, ,chemical drug, ,-0.288, ,0.008,-0.315,3.61E-05,"ACACA,CCN1,CPT1A,CRH,CYP51A1,FDPS,HMGCS1,IDI1,JUN,LDLR,Marcks,MVK,NSDHL,PIP4K2C,PLAT,PXN,SCD"
HSF1,-0.156,transcription regulator, ,-1.287, ,0.031,-1.356,4.16E-05,"ACACA,CCN2,CLU,Cox5b,FASN,JUN,LDLR,NFATC2,RANGAP1,SCD,SHC1"
cobalt chloride, ,chemical reagent,Activated,2.592, ,0.098,2.338,4.28E-05,"ADM,BNIP3,CLU,DDIT4,NDRG1,PROM1,TFRC"
carbon tetrachloride, ,chemical toxicant, ,-0.132, ,0.089,-0.394,4.51E-05,"CCN2,FGG,IGF2R,IGFBP5,JUN,MAPK3,Mt2,PECAM1,PRKCH,PROM1,TIMP3"
CFTR, ,ion channel, ,1.254, ,-0.011,1.283,4.63E-05,"FADS1,FADS2,FDPS,IDI1,MYL7,SCD,Scd2"
dihydrotestosterone, ,chemical - endogenous mammalian, ,0.76, ,0.069,0.481,4.77E-05,"ACACA,ADM,CCN2,CLU,CPT1A,DHCR24,FASN,IGFBP5,JUN,LDLR,MAF,NDRG1,PMEPA1,RAD23A,SCD,SELENBP1,SHC1,SLC16A6,TIMP3"
DGAT2,0.436,enzyme, , , , , ,4.80E-05,"ACACA,DGAT2,SCD"
triolein, ,chemical drug, , , , , ,4.80E-05,"FADS1,FADS2,FASN"
FGF19, ,growth factor, , , , , ,4.99E-05,"ACACA,FABP5,FASN,FDPS,PROM1,SCD,Scd2"
8-bromo-cAMP, ,chemical reagent, ,-0.543, ,0.081,-0.795,5.26E-05,"ADM,CCN2,CLU,CRH,ITPR3,JUN,LDLR,Nes,PLAT,SHC1"
ESR1, ,ligand-dependent nuclear receptor, ,-0.091, ,0.02,-0.183,5.32E-05,"ACACA,ANXA3,CASP6,CCN1,CENPL,CHRM2,COG7,Cox5b,DDIT4,DHCR24,DUSP10,EML1,FASN,FGF12,FXYD6,HEY1,HSPA2,IGFBP5,ITGA6,JUN,LDLR,MRPL52,NDUFA11,PRKCH,PROM1,PSAT1,ROBO2,SCD,Scd2,STAT5B,TFRC,TRAK1,ZNF367"
PTEN,-0.105,phosphatase, ,1.248, ,-0.005,1.266,5.35E-05,"ACACA,ADM,CTSV,FASN,GPM6A,HMGCS1,IDI1,IGFBP5,ITPR3,LDLR,MRPL12,NDRG1,NTS,PECAM1,PXN,RANGAP1,SCD,SDC4,STAT5B,TNFRSF9,VEGFB"
Ca2+, ,chemical - endogenous mammalian, ,0.905, ,0.078,0.65,5.52E-05,"CCN1,FABP5,FASN,GRIP1,HDC,IL33,ITGA6,ITPR3,JUN,NDRG1,Nes,NFATC2"
xanthohumol, ,chemical drug, ,0.447, ,-0.118,0.711,5.70E-05,"ACACA,DGAT2,FASN,SCD,SLN"
NR0B2,-0.162,ligand-dependent nuclear receptor, ,1.091, ,-0.109,1.305,5.80E-05,"ACACA,CCN2,CPT1A,CYP51A1,FASN,HDC,SCD"
SCD,-1.04,enzyme,Inhibited,-2.37, ,-0.043,-2.268,6.42E-05,"ACACA,ANGPTL4,CPT1A,FASN,Scd2,TNFRSF9"
CIDEC, ,other, ,-1.33, ,-0.088,-1.143,6.50E-05,"Cox5b,CPT1A,DGAT2,FASN,SCD"
NUPR1,0.211,transcription regulator, ,0.093, ,-0.043,0.269,6.59E-05,"ADM,AKAP12,BNIP3,CARMIL1,CCN1,CENPL,DHCR24,EXTL2,FAM114A1,HSPA2,IRF2BP2,ITPR3,NDRG1,Nes,SLC16A6,SLC25A20,SPC25"
CYB5R4,-0.09,enzyme, ,0.747, ,-0.13,1.002,6.65E-05,"FASN,Mt2,SCD,Scd2"
GW3965, ,chemical reagent, ,-1.166, ,-0.015,-1.126,7.05E-05,"DGAT2,FABP5,FADS2,FASN,FDPS,LDLR,PCYT2,SCD"
Vegf, ,group, ,-0.193, ,0.106,-0.599,7.08E-05,"AKAP12,ANGPTL4,CCN1,HDC,INSIG1,ITGA6,ITPR3,JUN,KIF20B,LDLR,LY75,Mt2,TBC1D8,TNFRSF9,UBE2C,VEGFB,VWF"
NR1D1,-0.001,ligand-dependent nuclear receptor, , , , , ,7.39E-05,"ACACA,BNIP3,CTSV,FADS2,FASN"
ARNT,0.017,transcription regulator, ,1.982, ,0.116,1.753,7.47E-05,"ADM,ANGPTL4,BNIP3,GAS1,LOXL2,RANGAP1,TFRC,UBE2C"
ACLY,-0.022,enzyme, , , , , ,7.62E-05,"ACACA,FASN,SCD"
C4BP, ,complex, , , , , ,7.62E-05,"CYP51A1,HMGCS1,IDI1"
miR-217-5p (and other miRNAs w/seed ACUGCAU), ,mature microrna, , , , , ,7.62E-05,"ACACA,FASN,SCD"
forskolin, ,chemical toxicant, ,1.05, ,0.069,0.798,8.10E-05,"ADM,AKAP12,BNIP3L,CCN2,CLU,CRH,CTSV,DDIT4,GRIP1,HSPA2,IGFBP5,ITPR3,JUN,MAPK3,Mt2,PLAT,PPM1F,RANGAP1,SHC1,Sik1,YBX3"
INS, ,other, ,-1.864, ,0.021,-1.917,8.39E-05,"ACACA,ADM,CCN1,CCN2,CPT1A,FASN,IGFBP5,JUN,SCD"
OGA,0.019,enzyme, ,1.291, ,-0.014,1.343,9.52E-05,"CAMK1D,FDPS,FGF13,FGF18,FLNB,GAS1,HMGCS1,IGFBP5,JUN,MMRN2,NDUFA11,NSDHL,PROM1,Scd2,TIMP3"
ESR2, ,ligand-dependent nuclear receptor,Inhibited,-2.138, ,0.025,-2.209,9.62E-05,"AKAP12,CCN2,CLU,DUSP10,FASN,HMGCS1,HSPA2,MAPK3,MSLN,NDRG1,PLAT,PRKCH,PROM1,PSAT1,SHC1,TENM4,VWF"
ACSS2,-0.036,enzyme, ,-1, ,0.144,-1.288,9.86E-05,"DGAT2,DHCR24,FASN,SCD"
BDNF, ,growth factor, ,0.115, ,0.061,-0.053,1.01E-04,"ANXA2,CCN1,CYGB,FLNB,HSD17B12,HSPA2,JUN,PRSS12,RYR3,Sik1,SPRED2,TBC1D8,TFRC"
UCP1, ,transporter, ,0.146, ,0.025,0.073,1.06E-04,"ACACA,ACOT2,CTSV,DKK3,EML1,FASN,PSAT1,SLN,TENM4"
STAT6,0.136,transcription regulator, ,0.422, ,0.019,0.355,1.08E-04,"Acot1,CAMK1D,CASP6,CPT1A,FADS1,FASN,IGF2R,IL33,LY75,MAF,MVK,NFATC2,Scd2,SELENBP1,STAT5B"
progesterone, ,chemical - endogenous mammalian,Activated,2.716, ,0.034,2.587,1.10E-04,"Acot1,ADM,CDT1,CRH,CTSF,CTSV,HDC,HEY1,HSPA2,IGFBP5,JUN,NDRG1,RYR3,SCD,Scd2,STAT5B,TBC1D8,TIMP3,VEGFB"
TEAD4,0.086,transcription regulator, ,0.277, ,0.093,0.071,1.16E-04,"ADM,CCN1,CCN2,DGAT2,IGFBP5,JUN,RHOBTB1"
CYP7A1, ,enzyme, ,-1.982, ,-0.006,-1.97,1.18E-04,"ACACA,FASN,FDPS,LDLR"
Pde4, ,group, ,1.982, ,-0.044,2.069,1.18E-04,"CRH,CYP51A1,FDPS,LDLR"
fibric acid derivative, ,chemical drug, ,-0.339, ,0.026,-0.391,1.18E-04,"ACACA,FADS2,FASN,SCD"
pitavastatin, ,chemical drug, ,-1.987, ,0.119,-2.223,1.18E-04,"CYP51A1,FDPS,HMGCS1,IDI1"
MYC,0.026,transcription regulator, ,-0.452, ,0.057,-0.721,1.22E-04,"ACACA,ADM,AKAP12,C1QBP,CLU,CPT1A,CPT2,CTNNAL1,CTSV,DDIT4,FABP5,FADS2,FASN,GAS1,ITGA6,JUN,MAPK3,MRPL12,Mt2,NDRG1,PECAM1,PROM1,PSAT1,SCAMP5,SCD,Scd2,TFRC,UBE2C,YBX3"
BATF2, ,other, , , , , ,1.27E-04,"CCN1,JUN"
RB1,-0.072,transcription regulator, ,-0.816, ,0.031,-0.893,1.27E-04,"BNIP3,CASP6,CCN2,CDT1,LOXL2,MAF,MAPK3,MRPL12,PMEPA1,PPFIBP1,PROM1,RYR3,SNTB2,TCAP,TNNI2,UBE2C"
FASN,-0.307,enzyme, ,-1.741, ,0.076,-1.926,1.29E-04,"ACACA,DDIT4,DGAT2,EDNRB,FASN,SCD"
ERG,0.026,transcription regulator,Activated,2.449, ,0.116,2.166,1.33E-04,"CAMK1D,FLNB,ITGA6,NDRG1,PECAM1,PLAT,PXN,RHOBTB1,RYR3,VWF"
MRTFB,-0.042,transcription regulator, ,0, ,0.063,-0.137,1.34E-04,"ADM,CCN1,CCN2,DHCR24,FADS2,IGFBP5,ITGA6,RHOBTB1,TAL1"
RIPK2,0.164,kinase, ,1.633, ,0.09,1.413,1.39E-04,"ACACA,DGAT2,FASN,IL33,LDLR,SCD"
TEAD1,-0.157,transcription regulator, ,0.816, ,0.109,0.549,1.39E-04,"ADM,CCN1,CCN2,IGFBP5,MSLN,RHOBTB1"
bromobenzene, ,chemical toxicant,Activated,2, ,0.01,1.981,1.39E-04,"CTSV,FDPS,HMGCS1,JUN,Mt2,TUBB2B"
IL13, ,cytokine, ,-1.17, ,0.069,-1.403,1.40E-04,"CASP6,CCN2,CTNNAL1,CTSV,DHCR24,DUSP10,FADS1,FADS2,FGG,HDC,JUN,MAF,NID1,SLC16A6,TFRC"
cephaloridine, ,chemical drug, ,-0.239, ,0.086,-0.466,1.40E-04,"ANGPTL4,CCN2,CDT1,DDIT4,FGB,TFRC,ZNF367"
DICER1,-0.018,enzyme, ,0, ,0.003,-0.009,1.56E-04,"ANGPTL4,ARID3A,CCN1,CRH,DHCR24,IGF2R,ITGA6,JUN,LPAR3,MAF,RAD23A,RANGAP1"
SIK1/SIK1B, ,kinase, , , , , ,1.61E-04,"ACACA,FASN,SCD"
GNA14, ,enzyme, , , , , ,1.63E-04,"ADM,AKAP12,ANXA3,BNIP3,PLAT,SELENBP1"
JUN,-0.379,transcription regulator, ,-0.589, ,0.08,-0.835,1.64E-04,"AKAP12,ANXA2,CCN1,CCN2,CLU,CRH,CYGB,HEY1,IGF2R,JUN,MAF,MAPK3,NTS,PXDN,SCD,TIMP3"
NCOR-LXR-Oxysterol-RXR-9 cis RA, ,complex, ,-1, ,0.109,-1.219,1.66E-04,"ACACA,CYP51A1,FASN,SCD"
halofuginone, ,chemical drug, , , , , ,1.68E-04,"AKAP12,CCN2,CYGB,DKK3,EDNRB,FXYD6,PROM1,Scd2"
RXRA,-0.104,ligand-dependent nuclear receptor, ,-0.059, ,0.029,-0.129,1.71E-04,"ACACA,Acot1,CPT1A,CPT2,FABP5,FADS2,FASN,FGG,INSIG1,MMP11,MYL7,SCD"
LIF, ,cytokine, ,-1.886, ,0.038,-1.998,1.88E-04,"ACACA,FGB,FGG,HEY1,JUN,mt-Atp8,Nes,PECAM1,TAL1,VWF"
ritonavir, ,chemical drug, , , , , ,2.15E-04,"CTNNAL1,ECT2,FADS2,FDPS,IDI1,LDLR,MVK,SCD"
tetradecanoylphorbol acetate, ,chemical drug, ,0.974, ,0.075,0.606,2.16E-04,"ADM,ANGPTL4,BNIP3L,CCN1,CCN2,CRH,CTSV,DDIT4,ECE1,HDC,HSPA2,IGFBP5,ITPR3,JUN,KLHL4,LBH,LDLR,LOXL2,MAF,MMP11,MRPL12,NTS,PECAM1,PLAT,PRKCH,SDC4,STAT5B,TEF"
desmosterol, ,chemical - endogenous mammalian, , , , , ,2.19E-04,"DHCR24,LDLR,Scd2"
TEAD3,0.148,transcription regulator, ,0.447, ,0.131,0.154,2.23E-04,"ADM,CCN1,CCN2,IGFBP5,RHOBTB1"
cerivastatin, ,chemical drug, ,-0.585, ,-0.013,-0.556,2.36E-04,"CCN2,FDPS,HMGCS1,IDI1,JUN,PLAT"
KRAS,0.012,enzyme, ,-1.803, ,0.004,-1.816,2.37E-04,"BDH1,BNIP3,CCN2,CDT1,CLU,FASN,GAS1,H1-2,IL33,JUN,LBH,MSLN,NETO2,PECAM1,PLAT,PPFIBP1,SCD,SDC4,TIMP3"
LDL, ,complex, ,0.333, ,0.081,0.109,2.40E-04,"CASP6,CCN2,ECE1,EDNRB,FDPS,INSIG1,JUN,LDLR,PECAM1,PLAT,SHC1"
hydrogen peroxide, ,chemical - endogenous mammalian, ,0.11, ,0.081,-0.183,2.56E-04,"ANXA2,CCN2,CLU,CYP51A1,DDIT4,DUSP10,FASN,FDPS,HDC,INSIG1,ITGA6,JUN,LDLR,SHC1,TFRC,TUBB2A"
NCOA2,-0.001,transcription regulator,Inhibited,-2.607, ,0.084,-2.826,2.68E-04,"CYP51A1,FASN,FGB,HMGCS1,IDI1,LDLR,NSDHL"
HSPA5,-0.039,enzyme, ,0.109, ,0.044,0.013,2.70E-04,"CLU,CPT1A,FASN,IDI1,SCD"
PNPLA2,0.069,enzyme, ,1.264, ,0.065,1.121,2.70E-04,"Acot1,ACOT2,CPT1A,CPT2,FASN"
TEAD2,0.067,transcription regulator, ,0.447, ,0.137,0.141,2.70E-04,"ADM,CCN1,CCN2,IGFBP5,RHOBTB1"
testosterone, ,chemical - endogenous mammalian, ,-1.379, ,0.064,-1.603,2.78E-04,"ANXA3,CLU,CTSV,CYP51A1,DDIT4,DHCR24,HDC,IGFBP5,IL33,JUN,NDRG1,PXN,TUBB2A"
PD98059, ,chemical - kinase inhibitor, ,0.19, ,-0.091,0.542,2.84E-04,"AKAP12,BDH1,BNIP3,CCN2,CLU,CRH,ECE1,EDNRB,FASN,INSIG1,JUN,LDLR,MAPK3,MMP11,PLAT,SELENBP1,TUBB2A"
8-hydroxyeicosapentaenoic acid, ,chemical - endogenous mammalian, , , , , ,2.90E-04,"ANGPTL4,CPT1A,CPT2"
CTNNBIP1,0.01,other, , , , , ,2.90E-04,"CYP51A1,HMGCS1,IDI1"
LAMTOR1,0.002,other, , , , , ,2.90E-04,"ACACA,FASN,SCD"
NRG4,-0.006,growth factor, , , , , ,2.90E-04,"ACACA,FASN,SCD"
carbohydrate, ,chemical - endogenous mammalian, ,-1.067, ,0.133,-1.331,3.01E-04,"ACACA,CPT1A,FASN,SCD"
MTORC1, ,complex, ,-1.86, ,0.113,-2.07,3.24E-04,"FASN,FDPS,IDI1,INSIG1,SCD"
ERBB3,-0.005,kinase, ,-1.134, ,0.019,-1.185,3.33E-04,"CCN1,CCN2,CLU,IGFBP5,NDRG1,NID1,TIMP3"
TGFB2,-0.014,growth factor, ,-0.96, ,0.057,-1.107,3.51E-04,"ANGPTL4,CCN2,GAS1,HEY1,NFATC2,PECAM1,SCD"
LY294002, ,chemical - kinase inhibitor, ,1.053, ,-0.11,1.478,3.53E-04,"ACACA,CCN1,CCN2,DHCR24,FASN,HMGCS1,IDI1,IGFBP5,JUN,MAF,NDRG1,NTS,SCD,SNTB2,UBE2C,VAMP1"
LMNB1,-0.084,other,Activated,2.219, ,-0.062,2.356,3.54E-04,"CYP51A1,FASN,HMGCS1,LDLR,SCD"
spironolactone, ,chemical drug,Activated,2.393, ,-0.044,2.5,3.55E-04,"ACACA,CCN2,EDNRB,FASN,SCD,TIMP3"
Creb, ,group, ,0.044, ,0.073,-0.158,3.64E-04,"ADM,CCN1,CPT1A,CRH,CTSV,CYP51A1,FLNB,JUN,LDLR,NTS,PLAT,PPFIBP1"
PEX5L, ,ion channel, , , , , ,3.73E-04,"FDPS,IDI1,MVK"
digoxin, ,chemical drug, , , , , ,3.73E-04,"ACACA,FASN,NDRG1"
bexarotene, ,chemical drug, ,1.455, ,0.062,1.271,3.73E-04,"CCN1,Cox5b,DDIT4,LOXL2,MAF,Nes,NTS,PLAT,SCD"
AMOT,0.177,other, , , , , ,3.78E-04,"CCN1,CCN2"
AMOTL1,0.094,other, , , , , ,3.78E-04,"CCN1,CCN2"
AMOTL2,-0.053,other, , , , , ,3.78E-04,"CCN1,CCN2"
ELOVL2, ,enzyme, , , , , ,3.78E-04,"FASN,SCD"
Fascin, ,group, , , , , ,3.78E-04,"CCN1,CCN2"
G protein beta gamma, ,complex, , , , , ,3.78E-04,"CCN1,CCN2"
Ggtase I, ,complex, , , , , ,3.78E-04,"CCN1,CCN2"
phosphoramidon, ,chemical - endogenous non-mammalian, , , , , ,3.78E-04,"ECE1,EDNRB"
tolylfluanid, ,chemical toxicant, , , , , ,3.78E-04,"FASN,SCD"
mycophenolic acid, ,chemical drug, ,0.816, ,0.092,0.591,4.04E-04,"ADM,AKAP12,CCN1,CCN2,CLU,LDLR"
"1,4-bis[2-(3,5-dichloropyridyloxy)]benzene", ,chemical toxicant, ,0.644, ,0.094,0.399,4.10E-04,"ACACA,CPT1A,FASN,IGF2R,INSIG1,SCD,STEAP4"
actinomycin D, ,biologic drug, ,0.736, ,-0.072,0.961,4.19E-04,"ADM,CCN1,CCN2,FASN,FGB,IGFBP5,ITPR3,JUN,PXN,TNFRSF9"
NPC1,0.137,transporter, , , , , ,4.30E-04,"CYP51A1,HMGCS1,IDI1,LDLR,MVK,SCD"
Insulin, ,group, ,-1.486, ,0.039,-1.617,4.44E-04,"ACACA,ANGPTL4,CCN2,Cox5b,CRH,DDIT4,DGAT2,FADS1,FADS2,FASN,FGB,INSIG1,JUN,SCD,Scd2"
indomethacin, ,chemical drug, ,0.213, ,0.043,0.086,4.48E-04,"ANXA2,CLU,CPT1A,CRH,FASN,FGB,FGF18,LDLR,LOXL2,PROM1"
EFNA2,-0.026,kinase, ,0.447, ,0.011,0.422,4.56E-04,"CCN2,FABP5,PLAT,PXN,UBE2C"
ATXN7,0.043,other, , , , , ,4.71E-04,"IGFBP5,Marcks,Sik1"
IL5, ,cytokine, ,0.302, ,0.137,-0.153,4.83E-04,"ANXA2,BNIP3,BNIP3L,DENND11,IDI1,NDRG1,PSAT1,RIPOR2,Scd2,TNFRSF9,TUBB2B"
miR-29b-3p (and other miRNAs w/seed AGCACCA), ,mature microrna, ,-0.647, ,-0.144,-0.3,4.86E-04,"ANGPTL4,COL4A5,INSIG1,LOXL2,NID1,TUBB2A"
GPER1, ,g-protein coupled receptor, ,-1.475, ,0.119,-1.732,4.94E-04,"CCN1,CCN2,DDIT4,FASN,JUN"
CD38,0.092,enzyme, ,0.768, ,0.129,0.408,5.00E-04,"ANXA2,BNIP3,BNIP3L,DENND11,NDRG1,PSAT1,Scd2,TUBB2B"
HSD11B1, ,enzyme, , , , , ,5.00E-04,"ACACA,ANGPTL4,CPT1A,FASN"
NPPB, ,other, ,1.98, ,-0.099,2.176,5.00E-04,"CCN2,HMGCS1,IDI1,LDLR"
lithium chloride, ,chemical drug, ,-1.195, ,0.077,-1.398,5.00E-04,"CYP51A1,FDPS,HMGCS1,IDI1,Marcks,PXN,RSPO1"
NFKBIA,0.188,transcription regulator, ,0.311, ,0.041,0.172,5.32E-04,"BNIP3,CLU,CTSF,HEY1,IGF2R,IL33,JUN,Mt2,NID1,PLAT,PMEPA1,SDC4,TFRC,TIMP3"
MAPK9,0.071,kinase, ,-0.8, ,0.061,-0.972,5.65E-04,"ACACA,CCN2,CDT1,FASN,HDC,JUN,PLAT,SCD"
amlodipine, ,chemical drug, , , , , ,5.84E-04,"ANXA2,IGFBP5,LDLR"
orotic acid, ,chemical - endogenous mammalian, , , , , ,5.84E-04,"ACACA,FASN,SCD"
sea cucumber body wall meal, ,chemical reagent, , , , , ,5.84E-04,"ACACA,CPT1A,FASN"
PRKAG3,-0.211,other, , , , , ,6.12E-04,"ANGPTL4,DUSP10,FXYD6,IGFBP5,ITGA6,LMCD1,Scd2,TFRC"
SETD2,-0.084,enzyme, ,1, ,-0.062,1.123,6.29E-04,"CCN1,CCN2,JUN,VEGFB"
methylnitrosourea, ,chemical toxicant, , , , , ,6.29E-04,"CLU,FASN,JUN,TIMP3"
STAT3,0.081,transcription regulator, ,1.077, ,0.071,0.804,6.94E-04,"ADM,ANGPTL4,BNIP3L,CCN2,ECT2,FASN,FGB,FGG,HEY1,IGFBP5,MAF,mt-Atp8,NDRG1,NFATC2,PECAM1,PROM1,SLFN13"
ACACB,-0.027,enzyme, , , , , ,7.13E-04,"ACACA,FASN,SCD"
IGF2,0.059,growth factor, , , , , ,7.16E-04,"CASP6,CCN2,CTSV,GAS1,IGF2R,IGFBP5,MMP11,NDRG1"
genistein, ,chemical drug, ,1.222, ,0.039,1.09,7.40E-04,"ADM,ANGPTL4,CCN2,CLU,CTSF,CTSO,CTSV,EXTL2,IGF2R,JUN,LDLR,MAN2B1,PLAT"
cisplatin, ,chemical drug, ,0.626, ,0.054,0.435,7.45E-04,"ANXA2,BNIP3L,CASP6,CCN2,CLU,CPT1A,CPT2,DDIT4,ECE1,FASN,FGB,GAS1,HMGCS1,JUN,PIP4K2C,PLAT,PROM1,PXN,TIMP3,ZNF334"
PSME3,0.032,peptidase, , , , , ,7.49E-04,"ACACA,FASN"
SRT2183, ,chemical reagent, , , , , ,7.49E-04,"FASN,LDLR"
ibotenic acid, ,chemical toxicant, , , , , ,7.49E-04,"CRH,JUN"
methylpiperidinyl-3b-hydroxycholenamide, ,chemical reagent, , , , , ,7.49E-04,"DHCR24,LDLR"
ATF6,0.07,transcription regulator, ,0.555, ,0.11,0.31,7.79E-04,"CPT1A,CPT2,FDPS,PLAT,UBE2C"
NORAD, ,other,Inhibited,-2, ,0.136,-2.272,7.80E-04,"CCN1,CCN2,JUN,LMCD1"
MTOR,0.058,kinase, ,0.895, ,0.043,0.774,7.90E-04,"ACACA,ADM,BNIP3,CPT2,DDIT4,FABP5,FASN,FDPS,FGB,NEURL1B,PECAM1,UBE2C"
LDLR,-0.338,transporter, , , , , ,8.09E-04,"ACACA,FABP5,FADS2,FASN,FDPS,LDLR,PCYT2,SCD,UBE2C"
tunicamycin, ,chemical - endogenous non-mammalian, ,0.388, ,0.079,0.184,8.09E-04,"ACACA,CPT1A,CPT2,DDIT4,DGAT2,FASN,NDRG1,PROM1,SCD"
CDK19,0.093,kinase, ,0.447, ,-0.102,0.675,8.15E-04,"CLU,DDIT4,FADS2,HMGCS1,JUN,MVK"
SP1,-0.002,transcription regulator, ,0.141, ,0.125,-0.105,8.33E-04,"AKAP12,BNIP3L,C1QBP,CCN2,CYP51A1,DHCR24,FASN,HDC,JUN,LDLR,Marcks,MMP11,NDRG1,PROM1,TIMP3,VWF"
tributyrin, ,chemical drug, ,0.555, ,0.135,0.255,8.36E-04,"ADM,AKAP12,CCN1,CCN2,NDRG1"
UCP2,0.308,transporter, , , , , ,8.58E-04,"FASN,HDC,SCD"
glutamyl-Se-methylselenocysteine, ,chemical - endogenous mammalian, , , , , ,8.58E-04,"CLU,JUN,TIMP3"
LGALS3,0.273,other, , , , , ,8.60E-04,"CTSF,CTSV,IGFBP5,ITGA6,ITPR3,NFATC2"
calcitriol, ,chemical drug, ,-0.736, ,-0.013,-0.688,8.64E-04,"ANXA2,CCN1,CDT1,CPT1A,DUSP10,ECH1,ECT2,FASN,FDPS,FGG,IGFBP5,JUN,LBH,MAF,PMEPA1,SLC13A1"
THRA,0.029,ligand-dependent nuclear receptor, ,-1.414, ,0.009,-1.427,8.70E-04,"ACACA,ANGPTL4,CPT1A,FASN,JUN,LDLR,PROM1"
EFNA1,0.051,other, ,0.447, ,-0.031,0.516,8.96E-04,"CCN2,FABP5,PLAT,PXN,UBE2C"
ADIPOQ, ,other, ,-1.616, ,0.015,-1.656,8.97E-04,"ACACA,CASP6,CCN2,CRH,FASN,LDLR,SCD,SHC1"
KDM5B,0.101,transcription regulator, ,0.954, ,-0.07,1.124,9.09E-04,"CCN2,DHCR24,ECT2,FABP5,INSIG1,TAL1,TUBB2A"
aspirin, ,chemical drug,Inhibited,-2.121, ,-0.087,-1.875,9.30E-04,"ADM,AKAP12,EDNRB,FGF18,HEY1,ITGA6,MMP11,PECAM1"
sucrose, ,chemical - endogenous mammalian, ,-1.715, ,0.113,-1.909,9.54E-04,"ACACA,CRH,FASN,SCD"
AHR,0.084,ligand-dependent nuclear receptor, ,-1, ,0.016,-1.052,9.57E-04,"ACACA,ADM,GAS1,ITGA6,JUN,Mt2,NID1,Pcp4l1,PLAT,SCD,STEAP4,TIMP3"
15(S)-HETE, ,chemical - endogenous mammalian, , , , , ,1.02E-03,"JUN,MAPK3,PECAM1"
AGPAT2,0.134,enzyme, , , , , ,1.02E-03,"ACACA,FASN,SCD"
ATP2A2,-0.016,transporter, , , , , ,1.02E-03,"DGAT2,FASN,SCD"
acadesine, ,chemical drug, , , , , ,1.02E-03,"ACACA,FASN,LDLR"
mannitol, ,chemical - endogenous mammalian, , , , , ,1.02E-03,"CCN2,HDC,JUN"
NRG1, ,growth factor, ,0.861, ,0.081,0.651,1.04E-03,"BNIP3,CCN1,CCN2,FABP5,IDI1,JUN,MAF,NDRG1,PXN,VEGFB"
YAP1,-0.025,transcription regulator, , , , , ,1.04E-03,"ACACA,CCN1,CCN2,CPT1A,CPT2,FASN,HMGCS1,MSLN,NDUFS8,TFRC"
IL4, ,cytokine, ,1.758, ,0.075,1.429,1.05E-03,"ANXA2,BNIP3,BNIP3L,CAMK1D,CASP6,CCN2,FADS1,FASN,FLNB,IGF2R,IL33,JUN,LY75,MAF,MAPK3,MVK,NDRG1,NFATC2,Scd2,STAT5B,TFRC,TIMP3,TNFRSF9"
carbamylcholine, ,chemical drug, ,-1.24, ,0.07,-1.378,1.05E-03,"CHRM2,ECE1,ITPR3,JUN"
SPDEF, ,transcription regulator, ,-0.447, ,-0.094,-0.236,1.10E-03,"CCN2,COL4A5,DKK3,ITGA6,VEGFB"
ZBTB7B,-0.142,transcription regulator, ,-1, ,0.086,-1.173,1.10E-03,"Cox5b,ECH1,HMGCS1,HSD17B12,MAF"
F2R,0.132,g-protein coupled receptor, ,0.577, ,0.094,0.351,1.12E-03,"CCN1,CCN2,ECE1,ITGA6,PLAT,VWF"
NR1H2,-0.066,ligand-dependent nuclear receptor,Inhibited,-2.216, ,0.01,-2.237,1.12E-03,"ACACA,FASN,FDPS,LDLR,SCD,TNFRSF9"
vorinostat, ,chemical drug, ,1.265, ,0.006,1.246,1.13E-03,"CLU,CYP51A1,HMGCS1,IDI1,JUN,LDLR,MVK,NDRG1,NFIC,TAL1"
let-7a-5p (and other miRNAs w/seed GAGGUAG), ,mature microrna, ,-0.898, ,-0.144,-0.497,1.19E-03,"AARSD1,COL4A5,FADS2,LOXL2,NID1,PXDN,SCD,TUSC2"
MTM1,-0.141,phosphatase, , , , , ,1.20E-03,"BNIP3,BNIP3L,CTSV"
NUMB,0.103,other, , , , , ,1.20E-03,"HEY1,Mt2,PROM1"
FA2H, ,enzyme, , , , , ,1.24E-03,"FASN,SCD"
GYS2, ,enzyme, , , , , ,1.24E-03,"ACACA,FASN"
LSP1,0.112,other, , , , , ,1.24E-03,"ITGA6,PECAM1"
MIR4269, ,microrna, , , , , ,1.24E-03,"CCN1,CCN2"
PCA3, ,other, , , , , ,1.24E-03,"NDRG1,PMEPA1"
SLC22A2, ,transporter, , , , , ,1.24E-03,"CPT1A,CPT2"
TCOF1,0.007,transporter, , , , , ,1.25E-03,"ADM,ANXA2,BNIP3,BNIP3L,NDRG1"
NR4A1,-0.085,ligand-dependent nuclear receptor, ,1.067, ,-0.03,1.128,1.26E-03,"ACACA,ADM,FASN,HDC,LDLR,NDUFS6,NDUFS8,SCD,TNFRSF9,UBE2C"
THRB,0.379,ligand-dependent nuclear receptor, ,-0.128, ,0.015,-0.164,1.26E-03,"ACACA,CPT1A,FASN,FDPS,H1-2,JUN,LDLR,MAPK3,PROM1,STAT5B"
EFNA4,0.187,kinase, ,1, ,-0.034,1.069,1.26E-03,"CCN2,FABP5,PLAT,UBE2C"
NKX2-5,-0.307,transcription regulator, ,0.338, ,0.108,0.131,1.26E-03,"ACACA,BMP10,ECE1,Nes"
IGF1,-0.009,growth factor, ,-0.036, ,0.069,-0.289,1.30E-03,"ACACA,ADM,CCN1,CCN2,CLU,DDIT4,FASN,HDC,IGFBP5,JUN,MAPK3,SCD,SPRED2,YBX3"
ATM,-0.118,kinase, ,0.555, ,0.093,0.348,1.33E-03,"CCN2,CLU,DUSP10,IL33,JUN"
Esrra,-0.181,transcription regulator,Inhibited,-2, ,0.036,-2.073,1.36E-03,"BDH1,Cox5b,CPT1A,CPT2,ECH1,Scd2"
Growth hormone, ,group, ,-0.785, ,0.06,-0.93,1.37E-03,"ACACA,ANGPTL4,CLU,FASN,FDPS,FGG,IGFBP5,JUN,LDLR"
EFNA3, ,kinase, ,1, ,-0.03,1.06,1.38E-03,"CCN2,FABP5,PLAT,UBE2C"
IAPP, ,other, , , , , ,1.40E-03,"CYP51A1,HMGCS1,IDI1"
MLX,-0.067,transcription regulator, , , , , ,1.40E-03,"ACACA,FASN,SCD"
WT1,0.238,transcription regulator, ,1.199, ,0.02,1.161,1.46E-03,"CCN2,CTSV,FDPS,IDI1,MSLN,NDRG1,PECAM1,Scd2,TIMP3"
PGR, ,ligand-dependent nuclear receptor,Activated,3.076, ,0.091,2.795,1.48E-03,"CPT2,CRH,HSPA2,IGFBP5,ITGA6,NDRG1,PRKCH,SNTB2,STAT5B,TBC1D8"
PRL, ,cytokine, ,1.437, ,0.097,1.135,1.48E-03,"ANXA2,ANXA3,CLU,CRH,CTSV,IGFBP5,JUN,Marcks,PLAT,TECR"
IL1B, ,cytokine, ,0.792, ,0.056,0.55,1.52E-03,"ADM,ANGPTL4,CCN2,CRH,CTSF,DDIT4,FABP5,FGB,FGF18,FGG,IGFBP5,IL33,JUN,LDLR,MMP11,Mt2,NFATC2,PLAT,SDC4,TIMP3,TNFRSF9,UBE2L6"
plicamycin, ,chemical drug, ,-0.284, ,-0.059,-0.142,1.57E-03,"BNIP3L,CCN2,FASN,Marcks,PROM1,VWF"
MAPK1,-0.058,kinase, ,-0.493, ,0.001,-0.497,1.57E-03,"AKAP12,ANGPTL4,CCN2,HDC,IGSF9B,JUN,MAPK3,PRSS12,PSAT1,TNFRSF9,UBE2C,UBE2L6"
ADAM12,0.108,peptidase, ,-0.391, ,-0.036,-0.31,1.59E-03,"CCN2,COL4A5,IGFBP5,IL33,VWF"
FBN1,0.171,other, , , , , ,1.62E-03,"CCN1,CCN2,TIMP3"
FUT8,-0.077,enzyme, , , , , ,1.62E-03,"GAS1,PROM1,TFRC"
EFNA5,-0.126,kinase, ,1, ,-0.044,1.087,1.64E-03,"CCN2,FABP5,PLAT,UBE2C"
ZMPSTE24,-0.054,peptidase, ,-1.192, ,-0.072,-1.049,1.64E-03,"CTSV,DDIT4,IGFBP5,STAT5B"
dimethylnitrosamine, ,chemical toxicant, , , , , ,1.64E-03,"IGFBP5,MAPK3,Mt2,PRKCH"
IL6, ,cytokine, ,-0.286, ,0.075,-0.576,1.64E-03,"ADM,CCN2,CLU,CRH,FGB,FGG,IGFBP5,JUN,LDLR,MAF,Mt2,PECAM1,PLAT,PROM1,SPC25,STEAP4,TAL1,TFRC,UBE2C"
RORA,0.153,ligand-dependent nuclear receptor, , , , , ,1.67E-03,"ACOT2,DHCR24,FASN,Mt2,NSDHL,SCD,Scd2,SELENBP1"
SMAD7,0.232,transcription regulator, ,-0.24, ,-0.042,-0.131,1.73E-03,"CCN2,ITGA6,PLAT,PMEPA1,PROM1,SCD,TIMP3"
estrogen receptor, ,group, ,0, ,-0.002,0.006,1.73E-03,"AGO1,CCN2,COL4A5,FGF12,FGF13,JUN,LDLR,LOXL2,TIMP3"
D-fructose, ,chemical - endogenous mammalian, ,-0.849, ,0.115,-1.077,1.78E-03,"ACACA,FASN,SCD,TIMP3"
KLF1, ,transcription regulator, , , , , ,1.78E-03,"EPB41,KLF3,PECAM1,TFRC"
MED13,-0.036,transcription regulator, ,-1, ,-0.05,-0.9,1.78E-03,"ACACA,FASN,SCD,Sik1"
testosterone propionate, ,chemical drug, ,-1, ,0.048,-1.096,1.78E-03,"ADM,CLU,FDPS,LDLR"
bleomycin, ,chemical drug, ,0.137, ,0.126,-0.191,1.78E-03,"CCN2,HEY1,NFATC2,PLAT,SDC4,TIMP3,UBE2C,VWF"
IL3, ,cytokine, ,0.447, ,0.101,0.222,1.84E-03,"BNIP3L,CPT1A,ECH1,FASN,HSPA2,IL33,JUN,LY75,MAN2B1,TAL1,TNFRSF9"
F Actin, ,complex, , , , , ,1.85E-03,"CCN2,CTSV"
Fructus xanthii aqueous extract, ,chemical - endogenous non-mammalian, , , , , ,1.85E-03,"FASN,SCD"
RO4929097, ,chemical drug, , , , , ,1.85E-03,"HEY1,PECAM1"
YOD1,0.109,enzyme, , , , , ,1.85E-03,"CCN1,CCN2"
quinapril, ,chemical drug, , , , , ,1.85E-03,"ADM,CCN2"
taspoglutide, ,biologic drug, , , , , ,1.85E-03,"CPT1A,FABP5"
CREBBP,0.026,transcription regulator, ,0.152, ,0.094,-0.034,1.86E-03,"AKAP12,CCN1,FDPS,HMGCS1,ITGA6,JUN,KLHL4,LDLR,MAF,MMP11,NDRG1,SDC4"
cytokine, ,group, ,-1.408, ,0.114,-1.686,1.86E-03,"CCN1,CLU,CRH,ITGA6,JUN,PLAT,VWF"
LILRB1, ,transmembrane receptor, , , , , ,1.86E-03,"ADM,MAF,TENT5C"
selenomethylselenocysteine, ,chemical - endogenous mammalian, , , , , ,1.86E-03,"CLU,JUN,TIMP3"
RET, ,kinase, , , , , ,1.88E-03,"CLU,CTSV,EDNRB,ITGA6,MAF,TIMP3"
GCG, ,other,Activated,2.2, ,0.07,2.046,1.90E-03,"CCN2,CPT1A,FASN,FDPS,Sik1"
ABCA1,0.272,transporter, ,-0.429, ,-0.025,-0.383,1.93E-03,"CPT1A,CYP51A1,DGAT2,LDLR"
CREM,0.095,transcription regulator, , , , , ,1.93E-03,"CYP51A1,HMGCS1,IDI1,LDLR,Marcks,MVK,Sik1"
CEBPA, ,transcription regulator, ,-0.414, ,0.049,-0.558,1.98E-03,"ACACA,AKAP12,CPT1A,DGAT2,EEF1A2,EXTL2,FASN,GAS1,JUN,NFATC2,SCD,STEAP4,TUBB2A"
EDN1,-0.051,cytokine, ,-0.234, ,0.115,-0.551,2.02E-03,"CCN1,CCN2,EDNRB,HEY1,JUN,PXN,TIMP3,VWF"
ADRA1B,-0.103,g-protein coupled receptor, , , , , ,2.08E-03,"CTSV,FABP5,JUN,Scd2"
ADRA1D, ,g-protein coupled receptor, , , , , ,2.08E-03,"CTSV,FABP5,JUN,Scd2"
MYBL2,-0.127,transcription regulator, , , , , ,2.08E-03,"CASP6,CLU,IGFBP5,UBE2C"
n-3 fatty acids, ,chemical drug,Activated,2, ,-0.018,2.035,2.08E-03,"FADS1,FADS2,FASN,SCD"
"9Z,11E-octadecadienoic acid", ,chemical - endogenous mammalian, , , , , ,2.13E-03,"FADS1,FASN,LDLR"
CL 316243, ,chemical drug, , , , , ,2.13E-03,"ACACA,FASN,SCD"
DL-fructose, ,chemical - endogenous mammalian, , , , , ,2.13E-03,"ACACA,FASN,SCD"
FGF4, ,growth factor, , , , , ,2.13E-03,"HMGCS1,SCD,Scd2"
FSHB, ,other, , , , , ,2.13E-03,"CCN2,FABP5,PLAT"
alvespimycin, ,chemical drug, , , , , ,2.13E-03,"ACACA,FASN,SCD"
GH1, ,growth factor, ,-0.794, ,0.027,-0.852,2.14E-03,"CLU,FASN,JUN,LDLR,RAD23A,SLC13A1"
AKT1,-0.047,kinase, ,0.641, ,0.062,0.521,2.16E-03,"CLU,CTSV,FABP5,FASN,HMGCS1,IGFBP5,NFATC2,PROM1,SCD,UBE2C"
USF1,-0.006,transcription regulator, , , , , ,2.24E-03,"AKAP12,CPT1A,FASN,IGF2R,LDLR"
TFE3,0.066,transcription regulator, ,0, ,0.117,-0.234,2.25E-03,"Cox5b,FASN,INSIG1,SCD"
"10E,12Z-octadecadienoic acid", ,chemical - endogenous mammalian, ,-0.293, ,0.008,-0.314,2.31E-03,"ACACA,CPT1A,DGAT2,FADS1,FASN,LDLR,SCD"
L-triiodothyronine, ,chemical - endogenous mammalian, ,-0.542, ,0.058,-0.746,2.35E-03,"ACOT2,ADM,BNIP3L,CCN2,CLU,CPT1A,ECE1,FASN,LDLR,NID1,PSAT1,SCD,Scd2"
oleoyl-estrone, ,chemical drug, , , , , ,2.41E-03,"ACACA,FASN,LDLR"
IL2, ,cytokine, ,0.348, ,0.087,0.043,2.42E-03,"CRH,FAM110A,FGF13,H1-2,IDI1,ITGA6,JUN,LDLR,MAF,NDRG1,NETO2,PECAM1,SPRED2,STAT5B,TFRC,TNFRSF9"
VEGFA,0.138,growth factor, ,0.939, ,0.108,0.603,2.43E-03,"CCN1,CCN2,CTSV,IGFBP5,NFATC2,PECAM1,PLAT,TAL1,TBC1D8,TNFRSF9"
HMGCR,-0.084,enzyme, , , , , ,2.56E-03,"CCN1,CCN2"
Muscarinic cholinergic receptor, ,group, , , , , ,2.56E-03,"CCN1,JUN"
SERPINA3, ,other, , , , , ,2.56E-03,"CCN2,LDLR"
SLC22A1,0.226,transporter, , , , , ,2.56E-03,"CPT1A,CPT2"
jasplakinolide, ,chemical - endogenous non-mammalian, , , , , ,2.56E-03,"CCN1,CCN2"
miR-139-5p (miRNAs w/seed CUACAGU), ,mature microrna, , , , , ,2.56E-03,"MMP11,SHC1"
penfluridol, ,chemical drug, , , , , ,2.56E-03,"ITGA6,PXN"
retroinverso ERG inhibitory peptide 1, ,chemical reagent, , , , , ,2.56E-03,"NDRG1,PLAT"
retroinverso ERG inhibitory peptide 2, ,chemical reagent, , , , , ,2.56E-03,"NDRG1,PLAT"
xestospongin C, ,chemical - endogenous non-mammalian, , , , , ,2.56E-03,"CRH,MAF"
KITLG,0.085,growth factor, ,0.283, ,0.115,0.056,2.60E-03,"CCN2,CLU,DHCR24,EDNRB,FABP5,LDLR,SHC1,TAL1,VWF"
ADRA1A, ,g-protein coupled receptor, , , , , ,2.61E-03,"CTSV,FABP5,JUN,Scd2"
EPHB4,0.079,kinase, ,1, ,0.093,0.814,2.61E-03,"MYL7,Nes,STAT5B,TAL1"
bicalutamide, ,chemical drug, ,-0.283, ,-0.081,-0.123,2.61E-03,"CLU,DDIT4,PMEPA1,SHC1"
triamcinolone acetonide, ,chemical drug, ,1.913, ,0.004,1.903,2.65E-03,"ANGPTL4,DUSP10,GAS1,INSIG1,JUN,LDLR,SCD,VWF"
ATF4,0.009,transcription regulator, ,-0.063, ,0.121,-0.353,2.66E-03,"CPT1A,DDIT4,FASN,IGFBP5,JUN,NDRG1,PSAT1"
NR1I2, ,ligand-dependent nuclear receptor, ,-1.883, ,0.034,-1.969,2.66E-03,"CPT1A,FASN,HMGCS1,INSIG1,JUN,NAT8B,SCD"
mono-(2-ethylhexyl)phthalate, ,chemical toxicant, ,0.378, ,0.126,0.044,2.66E-03,"ANGPTL4,CPT2,DDIT4,DGAT2,FADS1,FASN,LDLR"
COMMD1,-0.028,transporter, , , , , ,2.72E-03,"BNIP3,DDIT4,TFRC"
leukotriene B4, ,chemical - endogenous mammalian, , , , , ,2.72E-03,"CRH,FASN,JUN"
miR-155-5p (miRNAs w/seed UAAUGCU), ,mature microrna, ,1.72, ,-0.144,2.095,2.75E-03,"CCN1,CYP51A1,DNAJC19,FADS1,HSD17B12,LCLAT1,MAF"
CDX1, ,transcription regulator,Activated,2, ,0.003,1.993,2.80E-03,"CLU,HDC,HEPH,NTS"
homocysteine, ,chemical - endogenous mammalian, ,-0.776, ,0.067,-0.924,2.91E-03,"ANXA2,CLU,FDPS,IDI1,NDRG1"
LMNA,-0.129,other, , , , , ,2.96E-03,"CAMK1D,CCN2,DNAJC19,IGF2R,JUN,MYL7,Nes,SLN,TIMP3"
E2F5,0.096,transcription regulator, , , , , ,3.05E-03,"CASP6,DUSP10,VEGFB"
HAND1, ,transcription regulator, , , , , ,3.05E-03,"ACACA,CPT1A,HEY1"
SUPT16H,0.023,transcription regulator, , , , , ,3.05E-03,"H1-2,LOXL2,TNNI2"
TAF4B,-0.163,transcription regulator, , , , , ,3.05E-03,"CCN2,ITGA6,JUN"
NFYA,0.08,transcription regulator, , , , , ,3.06E-03,"FASN,JUN,SCD,Scd2,VWF"
TFRC,0.752,transporter, ,-0.128, ,-0.104,0.098,3.06E-03,"ANXA2,BNIP3,DDIT4,JUN,LY75"
corticosterone, ,chemical - endogenous mammalian, ,1.327, ,0.012,1.301,3.10E-03,"ACACA,CCN2,CRH,DDIT4,FASN,JUN"
TP63, ,transcription regulator, ,1.241, ,0.063,1.028,3.20E-03,"ADM,CCN1,CCN2,CPT2,CYGB,DDIT4,DKK3,DUSP10,FASN,FDPS,ITGA6,TIMP3,TUBB2B"
chenodeoxycholic acid, ,chemical - endogenous mammalian, ,-1.199, ,0.04,-1.277,3.22E-03,"CPT1A,FASN,FGB,FGG,LDLR"
DNMT3A,0.038,enzyme, ,0.378, ,-0.034,0.469,3.24E-03,"AKAP12,CASP6,ITPR3,NFATC2,SDC4,SHC1,SLN"
FGF2, ,growth factor, ,0.375, ,0.075,0.146,3.26E-03,"ADM,ANGPTL4,CCN1,CYGB,EDNRB,IGFBP5,JUN,Nes,PLAT,SCD,TIMP3,VWF"
COL18A1,0.145,other, ,-1.387, ,-0.112,-1.139,3.38E-03,"DDIT4,EDNRB,JUN,PECAM1,VWF"
"3,5-L-diiodothyronine", ,chemical - endogenous mammalian, , , , , ,3.39E-03,"CPT1A,SCD"
ACACA,-0.214,enzyme, , , , , ,3.39E-03,"FASN,SCD"
ANGPTL8, ,other, , , , , ,3.39E-03,"ACACA,SCD"
CHCHD5,-0.055,other, , , , , ,3.39E-03,"ACACA,FASN"
FBXL5,0.033,enzyme, , , , , ,3.39E-03,"Mt2,TFRC"
HINT1,-0.039,enzyme, , , , , ,3.39E-03,"FADS1,FADS2"
SLC39A14,0.049,transporter, , , , , ,3.39E-03,"FASN,SCD"
THRSP, ,other, , , , , ,3.39E-03,"ACACA,FASN"
chlorpyrifos, ,chemical toxicant, , , , , ,3.39E-03,"CRH,NTS"
meldonium, ,chemical drug, , , , , ,3.39E-03,"CPT1A,LDLR"
uridine, ,chemical - endogenous mammalian, , , , , ,3.39E-03,"Acot1,BDH1"
ziprasidone, ,chemical drug, , , , , ,3.39E-03,"CRH,HMGCS1"
BCAP31,-0.048,transporter, , , , , ,3.40E-03,"ACACA,INSIG1,SCD"
fluticasone propionate, ,chemical drug, ,1.134, ,0.005,1.12,3.57E-03,"ADM,ANGPTL4,DDIT4,SDC4,SLC16A6,TIMP3,VWF"
CEBPB, ,transcription regulator, ,1.004, ,0.094,0.695,3.58E-03,"ADM,CDT1,CPT1A,CRH,DGAT2,GAS1,HDC,JUN,LDLR,MMP11,NFATC2,SCD"
SIRT3,0.027,enzyme, ,0.656, ,-0.048,0.749,3.67E-03,"mt-Atp8,PECAM1,SCD,TFRC"
6-hydroxydopamine, ,chemical toxicant, ,0.447, ,0.073,0.284,3.71E-03,"BNIP3L,CRH,DDIT4,HEPH,JUN"
miR-335-3p (miRNAs w/seed UUUUCAU), ,mature microrna, , , , , ,3.77E-03,"COL4A5,LOXL2,NID1"
GW9662, ,chemical reagent, ,0.179, ,-0.048,0.285,3.89E-03,"ACACA,ANGPTL4,CCN2,FASN,INSIG1"
cycloheximide, ,chemical reagent, ,-1.114, ,-0.018,-1.061,3.94E-03,"ADM,CCN1,CCN2,DDIT4,IGFBP5,JUN,KLF3,MMP11,PLAT,PXN,SCD"
MYB, ,transcription regulator, ,1.473, ,0.057,1.348,4.05E-03,"ADM,CASP6,IGFBP5,JUN,MMP11,SDC4,TNFRSF9"
NR1H3,0.307,ligand-dependent nuclear receptor,Inhibited,-2.022, ,0.021,-2.075,4.15E-03,"ACACA,FASN,FDPS,LDLR,Mt2,SCD,TNFRSF9,UBE2C"
GW 4064, ,chemical toxicant, ,-0.958, ,0.069,-1.096,4.16E-03,"ACACA,FGB,FGG,SLC13A1"
SIRT6,-0.057,enzyme, , , , , ,4.16E-03,"FASN,IGF2R,MAPK3,SCD"
NFIL3,-0.086,transcription regulator, , , , , ,4.17E-03,"ACACA,FASN,SCD"
carbenoxolone, ,chemical toxicant, , , , , ,4.17E-03,"ACACA,CCN2,FASN"
gefitinib, ,chemical drug, , , , , ,4.18E-03,"CTNNAL1,ECT2,FGF18,IGFBP5,MMP11,SPRED2,TIMP3"
ATN1,-0.01,transcription regulator, , , , , ,4.20E-03,"ARHGEF28,IGFBP5,Marcks,NFIC,Sik1,VAMP1"
miR-125b-5p (and other miRNAs w/seed CCCUGAG), ,mature microrna, ,-0.179, ,-0.144,0.139,4.27E-03,"ARID3A,CASP6,JUN,PROM1,SCD"
EP300,-0.027,transcription regulator, , , , , ,4.30E-03,"AKAP12,CPT1A,CPT2,FASN,ITGA6,JUN,KLHL4,MAF,MMP11,NDRG1,SDC4,UBE2C"
11-dehydrocorticosterone, ,chemical - endogenous mammalian, , , , , ,4.33E-03,"ACACA,FASN"
GUSB,0.083,enzyme, , , , , ,4.33E-03,"CCN1,CTSV"
Mup1 (includes others), ,other, , , , , ,4.33E-03,"FASN,SCD"
UGT2B15, ,enzyme, , , , , ,4.33E-03,"RAD23A,SLC16A6"
UGT2B17, ,enzyme, , , , , ,4.33E-03,"RAD23A,SLC16A6"
tetrachlorodibenzodioxin, ,chemical toxicant, ,0.522, ,0.013,0.489,4.35E-03,"ACOT2,ADM,BMP10,CCN1,COL4A5,CTSV,HSPA2,INPP5A,JUN,Pcp4l1,STEAP4"
pravastatin, ,chemical drug, , , , , ,4.43E-03,"LDLR,SDC4,VWF,Xlr3c (includes others)"
TCF7L2,-0.167,transcription regulator, ,0, ,0.127,-0.358,4.45E-03,"CCN2,CTNNAL1,CYP51A1,DHCR24,HSPA2,KLHL4,KMT5A,LBH,LPAR3,PLAT"
LLGL2,0.139,other, , , , , ,4.60E-03,"CCN1,CCN2,NDRG1"
SIAH2,0.104,transcription regulator, , , , , ,4.60E-03,"DHCR24,NDRG1,PMEPA1"
ramipril, ,chemical drug, , , , , ,4.60E-03,"CCN2,COL4A5,CRH"
Mek, ,group, ,-0.003, ,0.049,-0.126,4.61E-03,"CCN2,CLU,FASN,ITGA6,JUN,MAF,SLC16A6,SPRED2"
HGF, ,growth factor, ,0.296, ,0.1,-0.029,4.66E-03,"AKAP12,ANGPTL4,CCN1,CCN2,INSIG1,ITGA6,ITPR3,KIF20B,LDLR,LY75,TBC1D8,TIMP3,UBE2C"
"2-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-1H-indol-5-ol", ,chemical reagent, ,1.091, ,-0.015,1.131,4.71E-03,"CCN2,CPT1A,DDIT4,DHCR24,H1-2,PMEPA1,SDC4"
MRTFA,0.021,transcription regulator, , , , , ,4.71E-03,"CCN1,CCN2,DHCR24,FADS2,ITGA6,RHOBTB1,TAL1"
VHL,0.035,transcription regulator, , , , , ,4.84E-03,"BNIP3,CCN2,CPT2,LOXL2,MAF,TFRC"
metformin, ,chemical drug, ,0.692, ,-0.024,0.745,4.85E-03,"ACACA,CCN2,DDIT4,FASN,INSIG1,ITGA6,VWF"
NCOR1,0.007,transcription regulator, , , , , ,4.88E-03,"CRH,DHCR24,FASN,NDRG1,PMEPA1"
FGFR4, ,kinase, , , , , ,5.05E-03,"ACACA,DGAT2,FASN"
NGFR,-0.102,transmembrane receptor, , , , , ,5.05E-03,"JUN,LDLR,PLAT"
thyroid hormone, ,chemical - endogenous mammalian, , , , , ,5.15E-03,"CPT1A,ECH1,FASN,FDPS,KLF3,MAPK3,STAT5B"
FBXW7,0.026,enzyme, ,0.152, ,-0.123,0.396,5.29E-03,"DGAT2,HEY1,JUN,LDLR"
cyclosporin A, ,biologic drug, ,-0.543, ,-0.043,-0.396,5.31E-03,"ANXA2,CCN2,CLU,DDIT4,EDNRB,FASN,FGB,JUN,LDLR,MAF,PRKCH,SCD"
Z-LLL-CHO, ,chemical - protease inhibitor, ,0.65, ,0.075,0.419,5.35E-03,"CCN2,CDT1,CLU,FASN,ITPR3,JUN,MMP11,PXN,RANGAP1,YBX3"
streptozocin, ,chemical drug, ,0.618, ,0.029,0.548,5.37E-03,"ACACA,CCN2,CLU,CPT1A,CPT2,FASN,SCD,SLC25A20"
ANGPTL3, ,growth factor, , , , , ,5.37E-03,"ACACA,SCD"
GNA11,-0.038,enzyme, , , , , ,5.37E-03,"CTSV,LMCD1"
Irp, ,group, , , , , ,5.37E-03,"HEPH,TFRC"
MLH1,-0.091,enzyme, , , , , ,5.37E-03,"BNIP3,CLU"
PCBP2,0.104,other, , , , , ,5.37E-03,"CCN1,CCN2"
RANBP9,-0.029,other, , , , , ,5.37E-03,"JUN,PXN"
Sik1,0.48,kinase, , , , , ,5.37E-03,"ACACA,FASN"
TEAD, ,group, , , , , ,5.37E-03,"CCN1,CCN2"
SOX4,0.004,transcription regulator, ,0.478, ,0.09,0.24,5.45E-03,"Acot1,FGF13,MMP11,PECAM1,PPM1F,TENM4,TUBB2B"
geldanamycin, ,chemical - endogenous non-mammalian,Activated,2.137, ,-0.041,2.251,5.49E-03,"AARSD1,ACACA,AGO1,ANXA2,CLU,FASN,IGF2R,JUN,LBH"
ALDH1A2,-0.019,enzyme, , , , , ,5.53E-03,"CCN1,CCN2,TIMP3"
ITCH,0.008,enzyme, , , , , ,5.53E-03,"CCN1,CCN2,TFRC"
PRKCZ,0.072,kinase, , , , , ,5.53E-03,"JUN,MAPK3,PSAT1"
ROR1,0.099,kinase, , , , , ,5.53E-03,"CCN1,CCN2,NDRG1"
Stat3-Stat3, ,complex, , , , , ,5.53E-03,"FGB,FGG,JUN"
deferasirox, ,chemical drug, , , , , ,5.53E-03,"ANXA2,JUN,LY75"
Fcer1, ,complex, , , , , ,5.60E-03,"IL33,JUN,NFATC2,TNFRSF9"
NRIP1,0.02,transcription regulator,Inhibited,-2, ,-0.073,-1.853,5.60E-03,"ACACA,FASN,SCD,SLC25A20"
OSMR,-0.001,transmembrane receptor, , , , , ,5.60E-03,"FASN,FGB,Mt2,SCD"
IKBKB,0.097,kinase,Activated,2.63, ,0.088,2.398,5.74E-03,"CCN2,CLU,CTSF,ECT2,FASN,Mt2,NID1,TIMP3,TNFRSF9"
STK11,-0.115,kinase, ,-1.414, ,0.037,-1.52,5.74E-03,"ALDH9A1,Cox5b,FGG,IGFBP5,IL33,NDUFA11,NDUFS8,PSAT1,SLC16A4"
estrogen, ,chemical drug, ,-0.117, ,0.094,-0.37,5.74E-03,"CCN1,CCN2,CLU,CRH,IGFBP5,JUN,LDLR,NTS,PLAT"
VDR,0.596,transcription regulator, ,-0.164, ,0.036,-0.266,5.79E-03,"ACACA,CDT1,CPT2,FGG,IGFBP5,JUN,LBH,LDLR"
PRKCD,-0.006,kinase, ,0.97, ,0.068,0.804,5.93E-03,"BNIP3,ITPR3,JUN,LBH,LDLR,PROM1,TUBB2A"
CDK4,0.059,kinase, , , , , ,5.94E-03,"CIP2A,GALNT11,GAS2L3,KIF20B,SPC25,ZNF367"
N-cor, ,group,Activated,2.216, ,-0.119,2.478,6.02E-03,"ACACA,FADS2,FASN,SCD,Scd2"
RXRG, ,ligand-dependent nuclear receptor, , , , , ,6.03E-03,"FABP5,MMP11,TIMP3"
SOST,0.057,other, , , , , ,6.03E-03,"ACACA,CPT1A,FASN"
SSRP1,0.053,transcription regulator, , , , , ,6.03E-03,"H1-2,LOXL2,TNNI2"
TIMP1,-0.171,cytokine, , , , , ,6.03E-03,"IL33,PLAT,TIMP3"
miR-221-3p (and other miRNAs w/seed GCUACAU), ,mature microrna, , , , , ,6.03E-03,"BNIP3L,DDIT4,TIMP3"
MAPK14,0.04,kinase,Activated,2.607, ,0.083,2.39,6.10E-03,"CYP51A1,FASN,FDPS,JUN,LDLR,PECAM1,SHC1"
CD3, ,complex, ,0.676, ,0.106,0.285,6.23E-03,"CASP6,EEF1A2,FDPS,IGFBP5,JUN,MAF,MSLN,NAGA,NFATC2,ORAI3,PCYT2,SHC1,TFRC,TNFRSF9,UBE2L6"
Nfat (family), ,group, ,-0.447, ,0.128,-0.734,6.27E-03,"CCN1,DKK3,FGF18,LBH,SDC4"
TAZ,0.043,enzyme, ,-1.479, ,0.093,-1.68,6.27E-03,"CCN1,CCN2,LDLR,LOXL2,VEGFB"
ciprofibrate, ,chemical drug, ,0.946, ,-0.006,0.96,6.34E-03,"ACOT2,ANXA2,CTSV,FGB,SCD,SELENBP1"
hydrocortisone, ,chemical - endogenous mammalian, ,-0.218, ,0.027,-0.283,6.34E-03,"ADM,CCN2,CRH,IGF2R,IGFBP5,LY75"
FSH, ,complex, ,-0.344, ,0.042,-0.433,6.43E-03,"ADM,AKAP12,BNIP3L,CCN2,CTSV,JUN,LDLR,PLAT,RANGAP1,TFRC,YBX3"
"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane", ,chemical - endogenous mammalian, , , , , ,6.52E-03,"CLU,IGFBP5"
NRBP2, ,kinase, , , , , ,6.52E-03,"ANXA2,PROM1"
SART1,0.056,other, , , , , ,6.52E-03,"DDIT4,PROM1"
hesperetin, ,chemical drug, , , , , ,6.52E-03,"DHCR24,LDLR"
sphingomyelin, ,chemical - endogenous mammalian, , , , , ,6.52E-03,"FASN,SCD"
EPO, ,cytokine, ,0.562, ,0.07,0.408,6.54E-03,"BNIP3L,CRH,DHCR24,FABP5,JUN,LDLR,TAL1,TFRC,VWF"
CDC42, ,enzyme, , , , , ,6.56E-03,"CCN2,JUN,UBE2C"
Calcineurin A, ,group, , , , , ,6.56E-03,"CCN2,FGF18,JUN"
KIN001-043, ,chemical - kinase inhibitor, , , , , ,6.56E-03,"Nes,PECAM1,SALL1"
miR-338-3p (miRNAs w/seed CCAGCAU), ,mature microrna, , , , , ,6.56E-03,"COL4A5,LOXL2,NID1"
Ngf, ,group, ,0.756, ,0.095,0.576,6.60E-03,"ANXA2,CLU,JUN,MAP1A"
MAP2K1,-0.016,kinase, , , , , ,6.63E-03,"CCN1,CCN2,FASN,HDC,JUN,LDLR,PECAM1"
SIRT1,0.001,transcription regulator, ,1.631, ,-0.052,1.777,6.90E-03,"BNIP3,CPT1A,CRH,FASN,GRIP1,LDLR,MVK,Scd2,TAL1,TBC1D8,TIMP3"
GHRL, ,growth factor, ,-1.951, ,0.032,-2.012,6.95E-03,"ACACA,CPT1A,FASN,SCD"
CCN2,-0.743,growth factor, ,-0.669, ,0.075,-0.83,7.07E-03,"CCN2,FLNB,JUN,SDC4,TIMP3"
APOB,-2.179,transporter, , , , , ,7.12E-03,"ACACA,FASN,SCD"
SU6656, ,chemical toxicant, , , , , ,7.12E-03,"ADM,CCN2,Mt2"
F3,0.143,transmembrane receptor, ,-1.091, ,0.144,-1.374,7.32E-03,"CCN1,CCN2,FGF13,MSLN"
lactacystin, ,chemical - protease inhibitor, ,0.378, ,0.059,0.222,7.58E-03,"IGFBP5,LDLR,MMP11,PXN,RANGAP1,SNTB2,TUBB2A"
thapsigargin, ,chemical toxicant, ,-0.114, ,0.078,-0.301,7.58E-03,"CLU,CPT1A,DDIT4,HDC,INSIG1,JUN,LBH"
propylthiouracil, ,chemical drug, , , , , ,7.64E-03,"FADS1,FADS2,ITGA6,JUN,PROM1"
H89, ,chemical - kinase inhibitor, ,-0.765, ,-0.104,-0.515,7.68E-03,"CRH,IGFBP5,ITPR3,NFATC2,NTS,SHC1"
CASP1, ,peptidase, , , , , ,7.70E-03,"ACACA,FASN,SCD"
amiodarone, ,chemical drug, , , , , ,7.70E-03,"FADS2,LDLR,SCD"
CDON,0.064,other, , , , , ,7.77E-03,"CCN2,TIMP3"
MTORC2, ,complex, , , , , ,7.77E-03,"ACACA,FASN"
Ncoa6,-0.056,transcription regulator, , , , , ,7.77E-03,"FASN,SCD"
clobetasol propionate, ,chemical drug, , , , , ,7.77E-03,"FABP5,LY75"
miR-375-3p (miRNAs w/seed UUGUUCG), ,mature microrna, , , , , ,7.77E-03,"C1QBP,CIP2A"
ulipristal acetate, ,chemical drug, , , , , ,7.77E-03,"ADM,VEGFB"
NR1I3,0.168,ligand-dependent nuclear receptor, ,0.277, ,0.12,0.011,7.93E-03,"FASN,IGF2R,INSIG1,SCD,STEAP4"
SOX2, ,transcription regulator, ,-0.201, ,0.041,-0.334,8.01E-03,"CCN2,CTNNAL1,DKK3,HEY1,JUN,LMCD1,Nes,PECAM1,PRKCH,PROM1,PSAT1,TIMP3"
methylselenic acid, ,chemical reagent, , , , , ,8.06E-03,"CLU,DHCR24,DUSP10,JUN,KIF20B,MAPK3,NDRG1,SCD"
2-deoxyglucose, ,chemical drug, ,0.009, ,-0.007,0.022,8.10E-03,"ACACA,CRH,DDIT4,JUN"
Nr1h, ,group, ,-1.751, ,-0.047,-1.637,8.16E-03,"ACACA,CPT2,ECE1,FASN,SCD,TIMP3"
Sos, ,group, , , , , ,8.20E-03,"ARID3A,IGFBP5,ITGA6,Mt2,NSDHL,PMEPA1,SCD"
U0126, ,chemical - kinase inhibitor, ,0.029, ,-0.097,0.324,8.29E-03,"ANGPTL4,CCN2,DUSP10,EDNRB,IDI1,ITGA6,JUN,LDLR,MAPK3,NETO2,PECAM1,SLC25A20,TIMP3"
GNRH, ,group, , , , , ,8.31E-03,"IGFBP5,JUN,MAPK3"
HDL-cholesterol, ,complex, , , , , ,8.31E-03,"CYP51A1,HMGCS1,IDI1"
PIAS1,-0.009,transcription regulator, , , , , ,8.31E-03,"ACACA,FASN,SCD"
diethylnitrosamine, ,chemical toxicant, , , , , ,8.55E-03,"JUN,Mt2,PECAM1,PROM1,SELENBP1"
CSF1,0.002,cytokine,Inhibited,-2.813, ,0.095,-3.081,8.62E-03,"CYP51A1,DHCR24,FDPS,HMGCS1,IDI1,JUN,MVK,NSDHL"
GATA4,-0.056,transcription regulator, ,0.218, ,0.038,0.145,8.63E-03,"ACACA,CCN2,CORIN,JUN,MYL7,NFATC2,TAL1"
wortmannin, ,chemical - kinase inhibitor, ,0.479, ,-0.074,0.672,8.63E-03,"ACACA,CCN2,FASN,JUN,MAF,PXN,TFRC"
PI3K (family), ,group, ,1.342, ,0.072,1.181,8.87E-03,"ADM,DDIT4,FASN,ITGA6,PXN"
LGALS1,0.048,other, ,1.114, ,0.083,0.953,8.94E-03,"EXTL2,INSIG1,MAF,TFRC"
CASZ1,-0.201,enzyme, , , , , ,8.95E-03,"FGF18,Sik1,TNNI2"
GDF9, ,growth factor, , , , , ,8.95E-03,"CCN2,ITGA6,PXN"
S-adenosylmethionine, ,chemical - endogenous mammalian, , , , , ,8.95E-03,"ACACA,FASN,MAF"
mevalonic acid, ,chemical - endogenous mammalian, , , , , ,8.95E-03,"FASN,LDLR,PLAT"
ANGPTL4,0.62,other, , , , , ,9.11E-03,"DGAT2,FASN"
CAMKK2,0.057,kinase, , , , , ,9.11E-03,"ACACA,FASN"
CHRM1, ,g-protein coupled receptor, , , , , ,9.11E-03,"CCN1,JUN"
CYP51A1,-0.359,enzyme, , , , , ,9.11E-03,"DHCR24,NSDHL"
FABP2, ,transporter, , , , , ,9.11E-03,"CPT1A,FASN"
FRS2,0.083,other, , , , , ,9.11E-03,"ITGA6,PROM1"
gamma-linolenic acid, ,chemical - endogenous mammalian, , , , , ,9.11E-03,"FASN,PLIN5"
mir-373, ,microrna, , , , , ,9.11E-03,"ANGPTL4,CSDC2"
sorbitol, ,chemical - endogenous mammalian, , , , , ,9.11E-03,"CCN1,CCN2"
L-glutamic acid, ,chemical - endogenous mammalian,Inhibited,-2.19, ,0.074,-2.352,9.19E-03,"FADS1,FADS2,FASN,JUN,Scd2"
Calcineurin protein(s), ,complex, ,0, ,0.083,-0.166,9.37E-03,"CTSV,CYGB,FGF18,NFATC2"
RORC,0.094,ligand-dependent nuclear receptor, , , , , ,9.47E-03,"ACOT2,DHCR24,Mt2,NSDHL,Scd2,SELENBP1"
NSUN6,-0.109,enzyme, , , , , ,9.61E-03,"CCN1,CCN2,NDRG1"
pregnenolone carbonitrile, ,chemical drug, , , , , ,9.61E-03,"CPT1A,INSIG1,SCD"
Brd4,-0.152,kinase,Activated,2, ,0.126,1.748,9.82E-03,"COL4A5,EDNRB,LOXL2,PLAT"
TGFB3,-0.11,growth factor, ,-1.387, ,0.105,-1.62,9.87E-03,"CCN1,CCN2,JUN,SCD,TIMP3"
TCF3,-0.069,transcription regulator, ,0.816, ,0.034,0.732,1.02E-02,"CASP6,CIP2A,CTSV,ECT2,JUN,MAF,NIBAN3,RIPOR2,SPC25,TENT5C"
IL17A, ,cytokine, ,0.322, ,0.099,0.087,1.03E-02,"CCN1,CCN2,IL33,JUN,KLF3,PECAM1,STEAP4,VWF"
Immunoglobulin, ,complex, ,-0.436, ,0.006,-0.453,1.03E-02,"ACACA,ADM,DDIT4,EDNRB,FAM110A,FASN,FLNB,HEY1,IL33,MAF,NDUFS6,NDUFS8,SCD,TFRC,YBX3"
NEUROG3, ,transcription regulator, ,0, ,0.14,-0.28,1.03E-02,"ACACA,CTSV,FASN,IGF2R"
ENG,0.026,transmembrane receptor, , , , , ,1.03E-02,"CCN2,ITGA6,PECAM1"
LG100268, ,chemical reagent, , , , , ,1.03E-02,"LDLR,NDRG1,SCD"
histone deacetylase, ,complex, , , , , ,1.03E-02,"CCN1,CRH,PLAT"
EGR2, ,transcription regulator, ,0.339, ,0.115,0.067,1.03E-02,"BNIP3L,CYP51A1,DDN,JUN,SCD,TFRC"
COL6A1,0.038,other, , , , , ,1.06E-02,"FASN,TNNI2"
DGAT1,0.034,enzyme, , , , , ,1.06E-02,"CPT1A,DGAT2"
F10, ,peptidase, , , , , ,1.06E-02,"CCN1,CCN2"
HOXA4, ,transcription regulator, , , , , ,1.06E-02,"CCN1,CCN2"
MGAT3,0.232,enzyme, , , , , ,1.06E-02,"HEY1,PROM1"
RGCC,-0.035,other, , , , , ,1.06E-02,"FASN,SCD"
anti-benzo(a)pyrene-diol-epoxide, ,chemical toxicant, , , , , ,1.06E-02,"BNIP3,JUN"
ginsenoside Rb1, ,chemical - endogenous non-mammalian, , , , , ,1.06E-02,"FASN,SCD"
nickel chloride, ,chemical toxicant, , , , , ,1.06E-02,"JUN,NDRG1"
octanoic acid, ,chemical - endogenous mammalian, , , , , ,1.06E-02,"DGAT2,FASN"
RAC1,-0.028,enzyme, ,-1.179, ,0.101,-1.375,1.06E-02,"CCN2,IL33,ITGA6,JUN,SHC1"
VCAN,-0.105,other, ,-1.633, ,0.015,-1.67,1.06E-02,"ADM,ANGPTL4,CLU,FABP5,MSLN,YBX3"
FAS,-0.085,transmembrane receptor, , , , , ,1.07E-02,"ANXA2,CCN2,DUSP10,JUN,LDLR,LY75,PECAM1,SHC1,SNTB2,TFRC"
ZNF217,0.078,transcription regulator,Inhibited,-2, ,-0.113,-1.773,1.08E-02,"ADM,KLHL4,PLAT,ZNF367"
CHUK,0.041,kinase, ,1.195, ,0.117,0.888,1.08E-02,"CLU,CTSF,HEY1,Mt2,NID1,TIMP3,VEGFB"
MAP4K4,0.011,kinase,Activated,2.213, ,-0.134,2.51,1.10E-02,"ACACA,FASN,NDUFA11,NDUFS8,SCD"
POSTN,0.028,other, , , , , ,1.10E-02,"HEY1,LOXL2,VEGFB"
T3-TR-RXR, ,complex, , , , , ,1.10E-02,"ACACA,FASN,LDLR"
sirolimus, ,chemical drug, ,0.816, ,-0.071,1.066,1.12E-02,"ACACA,ADM,CCN2,DDIT4,FASN,IDI1,IGFBP5,JUN,MAF,NTS,PROM1,SCD,TUBB2A"
CYP19A1, ,enzyme, , , , , ,1.13E-02,"ACACA,FASN,JUN,PXN"
LONP1,0.04,peptidase, , , , , ,1.13E-02,"ANXA2,C1QBP,MRPS22,NDUFA11"
(R)-PFI-2, ,chemical reagent, , , , , ,1.13E-02,CCN2
"(des-Arg10,Leu9)-kallidin", ,chemical reagent, , , , , ,1.13E-02,CCN2
"2,4-dichlorobenzamil", ,chemical reagent, , , , , ,1.13E-02,CCN2
"2-methoxy-5-(2',3',4'-trimethoxyphenyl)-2,4,6-cycloheptatrien-1-one", ,chemical reagent, , , , , ,1.13E-02,JUN
3-aminoisobutanoate, ,chemical - endogenous mammalian, , , , , ,1.13E-02,CPT1A
ALG10,-0.117,enzyme, , , , , ,1.13E-02,PROM1
ALG5,0.014,enzyme, , , , , ,1.13E-02,PROM1
ALG6,-0.001,enzyme, , , , , ,1.13E-02,PROM1
ALG8,-0.107,enzyme, , , , , ,1.13E-02,PROM1
BORCS8-MEF2B, ,transcription regulator, , , , , ,1.13E-02,JUN
CHMP3,-0.022,other, , , , , ,1.13E-02,IGF2R
CKAP4,-0.011,other, , , , , ,1.13E-02,CCN2
CLTA,0.055,other, , , , , ,1.13E-02,LDLR
CLTB,0.02,other, , , , , ,1.13E-02,LDLR
CORT-108297, ,chemical reagent, , , , , ,1.13E-02,CRH
DOK3, ,other, , , , , ,1.13E-02,NFATC2
FANK1, ,transcription regulator, , , , , ,1.13E-02,JUN
G-Actin, ,group, , , , , ,1.13E-02,JUN
GPR87, ,g-protein coupled receptor, , , , , ,1.13E-02,PROM1
GYPA, ,other, , , , , ,1.13E-02,Gypa
HNRNPDL,-0.013,other, , , , , ,1.13E-02,Cox5b
IPO5,-0.092,transporter, , , , , ,1.13E-02,IL33
KRT3, ,other, , , , , ,1.13E-02,PECAM1
LSM10,0.282,other, , , , , ,1.13E-02,H1-2
MAP1B,0.068,other, , , , , ,1.13E-02,MAP1A
MGAT4C, ,enzyme, , , , , ,1.13E-02,PROM1
MOB4,0.03,other, , , , , ,1.13E-02,CCN2
MOGS,0.133,enzyme, , , , , ,1.13E-02,PROM1
Mannosidase2, ,group, , , , , ,1.13E-02,PROM1
NEB,-0.095,other, , , , , ,1.13E-02,SLN
NSC117079, ,chemical reagent, , , , , ,1.13E-02,FGF18
OTP, ,transcription regulator, , , , , ,1.13E-02,CRH
PF-4523655, ,biologic drug, , , , , ,1.13E-02,DDIT4
PISD,-0.043,enzyme, , , , , ,1.13E-02,PCYT2
POU5F2,-0.321,transcription regulator, , , , , ,1.13E-02,CRH
Pde1, ,group, , , , , ,1.13E-02,CRH
R333, ,chemical drug, , , , , ,1.13E-02,MAF
RAB9A,-0.038,enzyme, , , , , ,1.13E-02,IGF2R
RNF7,0.009,enzyme, , , , , ,1.13E-02,JUN
SLC25A10,-0.145,transporter, , , , , ,1.13E-02,ACACA
alcuronium, ,chemical drug, , , , , ,1.13E-02,CHRM2
anti-miR-221 inhibitor, ,chemical reagent, , , , , ,1.13E-02,CCN2
anti-miR-222 inhibitor, ,chemical reagent, , , , , ,1.13E-02,CCN2
anti-miR-29a inhibitor, ,chemical reagent, , , , , ,1.13E-02,TIMP3
berberrubine, ,chemical - endogenous non-mammalian, , , , , ,1.13E-02,LDLR
beta-tocopherol, ,chemical - endogenous mammalian, , , , , ,1.13E-02,CCN2
columbamine, ,chemical - endogenous non-mammalian, , , , , ,1.13E-02,LDLR
daclizumab, ,biologic drug, , , , , ,1.13E-02,MAF
darifenacin, ,chemical drug, , , , , ,1.13E-02,CHRM2
direct black 38, ,chemical reagent, , , , , ,1.13E-02,TFRC
gallamine triethiodide, ,chemical drug, , , , , ,1.13E-02,CHRM2
impromidine, ,chemical drug, , , , , ,1.13E-02,LDLR
miR-502-5p (and other miRNAs w/seed UCCUUGC), ,mature microrna, , , , , ,1.13E-02,KMT5A
miR-657 (miRNAs w/seed GCAGGUU), ,mature microrna, , , , , ,1.13E-02,IGF2R
miR-6762-5p (and other miRNAs w/seed GGGGCCA), ,mature microrna, , , , , ,1.13E-02,USP22
miR-6825-5p (and other miRNAs w/seed GGGGAGG), ,mature microrna, , , , , ,1.13E-02,USP22
miR-6886-3p (miRNAs w/seed GCCCUUC), ,mature microrna, , , , , ,1.13E-02,USP22
mir-340, ,microrna, , , , , ,1.13E-02,PLAT
mirin, ,chemical reagent, , , , , ,1.13E-02,IL33
mubritinib, ,chemical drug, , , , , ,1.13E-02,MAF
podophyllotoxin, ,chemical drug, , , , , ,1.13E-02,CCN2
ponatinib, ,chemical drug, , , , , ,1.13E-02,DHCR24
proadifen, ,chemical reagent, , , , , ,1.13E-02,PLAT
ralaniten, ,chemical reagent, , , , , ,1.13E-02,UBE2C
remoxipride, ,chemical drug, , , , , ,1.13E-02,NTS
rhapontin, ,chemical - endogenous non-mammalian, , , , , ,1.13E-02,FASN
TWIST1,-0.025,transcription regulator, ,0.816, ,0.051,0.691,1.15E-02,"CLU,DKK3,IGFBP5,PROM1,PXDN,TIMP3"
doxorubicin, ,chemical drug, ,0.383, ,0.048,0.226,1.17E-02,"ADM,ANXA2,BNIP3L,CCN1,CCN2,CLU,FGB,JUN,KMT5A,NDRG1,PMEPA1"
ATF1,-0.006,transcription regulator, , , , , ,1.18E-02,"CYP51A1,JUN,NTS"
HRH3, ,g-protein coupled receptor, , , , , ,1.18E-02,"Acot1,ACOT2,Xlr3c (includes others)"
PCGEM1, ,other, , , , , ,1.18E-02,"ACACA,DHCR24,FASN"
PEBP1,0.019,other, , , , , ,1.18E-02,"ACACA,FASN,SCD"
SAHM1, ,chemical reagent, , , , , ,1.18E-02,"BNIP3,DDIT4,RHOBTB1"
phenacetin, ,chemical drug, , , , , ,1.18E-02,"ANXA2,CLU,FGB"
MAPT,-0.279,other, , , , , ,1.20E-02,"C1QBP,FASN,JUN,MAP1A,MAPK3,NDUFS6,NDUFS8,Pcp4l1,TUBB2A,TUBB2B"
ACE2, ,peptidase, , , , , ,1.21E-02,"BNIP3,CCN2"
BTC,-0.092,growth factor, , , , , ,1.21E-02,"ACACA,FASN"
EHHADH,0.163,enzyme, , , , , ,1.21E-02,"ACOT2,FASN"
miR-128-3p (and other miRNAs w/seed CACAGUG), ,mature microrna, , , , , ,1.21E-02,"AGO1,LDLR"
mir-140, ,microrna, , , , , ,1.21E-02,"BNIP3,LOXL2"
Laminin (complex), ,complex, , , , , ,1.26E-02,"ITGA6,PXN,SDC4"
lipid, ,chemical - endogenous mammalian, , , , , ,1.26E-02,"CLU,FDPS,LDLR"
verapamil, ,chemical drug, , , , , ,1.26E-02,"ANXA2,JUN,LDLR"
butyric acid, ,chemical - endogenous mammalian, ,-0.841, ,0.013,-0.878,1.27E-02,"ANXA2,CLU,DHCR24,FASN,H1-2,ITPR3,NFATC2,PLAT,STAT5B,TIMP3,VEGFB"
NKX2-3, ,transcription regulator, ,-1.906, ,0.003,-1.913,1.27E-02,"ADM,ANGPTL4,HEY1,NETO2,PRSS12,PSAT1,UBE2L6"
APOE,0.149,transporter, , , , , ,1.28E-02,"CCN1,CCN2,CLU,CPT1A,CTSV,JUN,LDLR,PMEPA1,SDC4"
HDAC5,-0.19,transcription regulator, , , , , ,1.28E-02,"CPT1A,CPT2,JUN,SCD"
NR1H4, ,ligand-dependent nuclear receptor, ,-0.555, ,-0.007,-0.54,1.29E-02,"ACACA,CPT2,FABP5,FASN,FGB,SLC13A1"
S100A9,0.095,other, ,0.128, ,0.046,0.017,1.29E-02,"AKAP12,DDIT4,IL33,PRSS12,ROBO2,TNFRSF9"
CLDN7, ,other, ,-0.391, ,0.002,-0.396,1.29E-02,"ANXA3,CCN2,ITPR3,NETO2,UBE2L6"
PRKCA,-0.096,kinase, ,-0.762, ,0.074,-0.909,1.29E-02,"BNIP3L,CCN2,HEY1,INSIG1,JUN"
SMARCA4,-0.056,transcription regulator, ,1.177, ,0.12,0.8,1.31E-02,"BNIP3L,CCN2,FGG,FLNB,GPM6A,HEPH,HEY1,IGFBP5,JUN,LOXL2,PLAT,TAL1,TNFRSF9,TNNI2"
PTH, ,other, ,0.621, ,0.092,0.444,1.32E-02,"CCN2,IGFBP5,IL33,JUN,PXN,SDC4"
benzo(a)pyrene, ,chemical toxicant, ,-0.447, ,0.063,-0.588,1.33E-02,"CCN1,ECT2,FASN,JUN,MAF,Mt2,SELENBP1"
LIPE,0.194,enzyme, , , , , ,1.34E-02,"FASN,ITGA6,SCD,Scd2,SDC4"
DLL4,0.221,other, , , , , ,1.34E-02,"HEY1,MAF,PECAM1"
SKIL,0.107,transcription regulator, , , , , ,1.34E-02,"NETO2,RHOBTB1,SLC16A6"
fulvestrant, ,chemical drug, ,1.969, ,-0.033,2.047,1.34E-02,"CCN1,DDIT4,DHCR24,IGFBP5,JUN,LDLR,TFRC,UBE2C"
Ige, ,complex, ,1.795, ,0.108,1.474,1.35E-02,"FXYD6,HDC,HSD17B12,IL33,Marcks,PECAM1,SCD,TFRC,TNFRSF9"
BHLHA15, ,transcription regulator, , , , , ,1.37E-02,"CLU,ITPR3"
HIF1AN,0.071,enzyme, , , , , ,1.37E-02,"ADM,HEY1"
OMA1,0.075,peptidase, , , , , ,1.37E-02,"FASN,SCD"
PCYT2,-0.28,enzyme, , , , , ,1.37E-02,"FASN,SCD"
SMURF2,0.097,enzyme, , , , , ,1.37E-02,"CCN2,JUN"
tributyltin, ,chemical reagent, , , , , ,1.38E-02,"ANGPTL4,CCN2,Cox5b,DGAT2,IL33"
NR3C1,0.015,ligand-dependent nuclear receptor, ,1.576, ,0.018,1.527,1.39E-02,"ADM,ANGPTL4,BNIP3L,CASP6,CCN1,CRH,DDIT4,DGAT2,GAS1,HSD17B12,IL33,JUN,MAPK3,TIMP3,TNFRSF9"
ZBTB17,-0.181,transcription regulator, , , , , ,1.39E-02,"ECT2,JUN,LDLR,UBE2C"
sodium chloride, ,chemical - endogenous mammalian, ,0, ,0.121,-0.243,1.39E-02,"CCN2,CRH,DDIT4,VWF"
CCND1,0.027,transcription regulator, , , , , ,1.40E-02,"CIP2A,DHCR24,GALNT11,GAS2L3,KIF20B,PMEPA1,SELENBP1,SPC25,ZNF367"
Collagen(s), ,complex, , , , , ,1.42E-02,"CCN1,PSAT1,PXN"
TXNIP,0.162,other, , , , , ,1.42E-02,"Acot1,DDIT4,FASN"
FGF1,-0.053,growth factor, ,0.447, ,-0.026,0.505,1.42E-02,"CCN1,CCN2,JUN,PMEPA1,TIMP3"
RUNX3, ,transcription regulator, ,0.152, ,-0.098,0.347,1.42E-02,"CCN1,CCN2,PXDN,RHOBTB1,VWF"
STAT5a/b, ,group,Inhibited,-2, ,0.042,-2.084,1.42E-02,"CLU,IDI1,MAF,NETO2,VWF"
tanespimycin, ,chemical drug,Activated,2.236, ,-0.073,2.398,1.47E-02,"ACACA,FASN,HMGCS1,JUN,SCD"
MASTL,-0.093,kinase, , , , , ,1.51E-02,"COPG2,SNTB2,TTC38"
ONECUT1, ,transcription regulator, , , , , ,1.51E-02,"BNIP3L,CYGB,CYP51A1,FABP5,FASN,KLF3,PPFIBP1,SCD"
zinc, ,chemical drug, ,1, ,-0.017,1.034,1.51E-02,"IDI1,SCD,SELENBP1,TFRC"
NFkB (complex), ,complex, ,1.518, ,0.122,1.121,1.52E-02,"ADM,CCN1,CCN2,CLU,EDNRB,FABP5,FGG,JUN,KLF3,PECAM1,PXN,SDC4,TFRC,TNFRSF9"
ALDH1A1,0.132,enzyme, , , , , ,1.54E-02,"ACACA,FASN"
TARBP2,-0.173,other, , , , , ,1.54E-02,"MAF,TNNI2"
ethidium, ,chemical drug, , , , , ,1.54E-02,"CCN1,CCN2"
p85 (pik3r), ,group, , , , , ,1.54E-02,"FASN,NDRG1"
KLF11,0.033,transcription regulator, , , , , ,1.56E-02,"CCN2,CPT2,PLAT,SLC25A20,TIMP3"
FOXA2, ,transcription regulator, ,0.152, ,0.046,0.061,1.59E-02,"CPT1A,DDIT4,FABP5,FGB,IGFBP5,IL33,SCD"
SPHK1, ,kinase, , , , , ,1.60E-02,"CCN2,IL33,JUN"
YY1,0.065,transcription regulator, ,-0.152, ,-0.011,-0.132,1.60E-02,"ARID3A,CLU,Cox5b,FDPS,IGFBP5,LDLR,VEGFB,VWF"
mir-21, ,microrna, ,-0.341, ,-0.094,-0.082,1.60E-02,"CLU,ECT2,Gvin1 (includes others),PECAM1,PLAT,TIMP3,TNFRSF9,UBE2L6"
5-fluorouracil, ,chemical drug,Activated,2.377, ,-0.035,2.48,1.60E-02,"ANXA2,BNIP3,BNIP3L,CLU,FDPS,JUN,NDUFS8,UBE2C,YBX3"
miR-124-3p (and other miRNAs w/seed AAGGCAC), ,mature microrna, ,1.153, ,-0.144,1.53,1.62E-02,"ALDH9A1,CCN2,DHCR24,LDLR,NFIC,NID1,ZNF367"
palmitic acid, ,chemical - endogenous mammalian, ,-1.812, ,0.057,-1.952,1.62E-02,"ACACA,CCN2,DGAT2,FASN,FDPS,Mt2,SCD"
TCF4,-0.053,transcription regulator, ,-1.195, ,0.042,-1.306,1.64E-02,"ANGPTL4,BNIP3,CIP2A,IGFBP5,JUN,NIBAN3,RIPOR2,SPC25,TENT5C,TRAK1"
HNRNPK,-0.001,transcription regulator, , , , , ,1.69E-02,"CCN2,ITGA6,LDLR"
lysophosphatidylinositol, ,chemical - endogenous mammalian, , , , , ,1.69E-02,"CPT1A,IL33,INSIG1"
omeprazole, ,chemical drug, , , , , ,1.69E-02,"CCN2,HDC,ITGA6"
ERBB4,0.009,kinase, ,-1, ,0.01,-1.02,1.70E-02,"IGFBP5,JUN,NID1,TIMP3"
haloperidol, ,chemical drug, ,-0.604, ,0.082,-0.764,1.70E-02,"CRH,HMGCS1,LDLR,NTS"
1-(carboxymethylthio)tetradecane, ,chemical drug, , , , , ,1.72E-02,"CPT2,SCD"
BARX2, ,transcription regulator, , , , , ,1.72E-02,"FGF12,TIMP3"
FDFT1,-0.255,enzyme, , , , , ,1.72E-02,"FASN,FDPS"
FMO3, ,enzyme, , , , , ,1.72E-02,"FASN,SCD"
FZD8,0.083,g-protein coupled receptor, , , , , ,1.72E-02,"CCN2,IGFBP5"
hemoglobin, ,complex, , , , , ,1.72E-02,"ADM,TFRC"
indirubin, ,chemical drug, , , , , ,1.72E-02,"CCN1,JUN"
lisinopril, ,biologic drug, , , , , ,1.72E-02,"JUN,LDLR"
KLF2,-0.248,transcription regulator, , , , , ,1.75E-02,"ADM,CCN2,NDRG1,PECAM1,TFRC,VWF"
TGFBR1,-0.005,kinase, ,-0.277, ,0.092,-0.457,1.76E-02,"CCN2,GAS1,HEY1,NFATC2"
mir-29, ,microrna, ,-1.98, ,-0.106,-1.77,1.76E-02,"ANGPTL4,COL4A5,NID1,TIMP3"
vancomycin, ,biologic drug, ,0.927, ,0.082,0.765,1.76E-02,"ANXA2,CLU,FGB,SCD"
ITGA5,0.019,transmembrane receptor, , , , , ,1.79E-02,"GAS1,JUN,PXN"
MAPK7,0.004,kinase, , , , , ,1.79E-02,"JUN,PLAT,STEAP4"
SCARB1,-0.123,transporter, , , , , ,1.79E-02,"DDIT4,FASN,LDLR"
4-hydroxytamoxifen, ,chemical drug, ,-0.666, ,0.074,-0.837,1.79E-02,"CCN1,CCN2,CLU,DDIT4,JUN,PRKCH"
ESRRA, ,ligand-dependent nuclear receptor, ,-1.342, ,0.127,-1.625,1.79E-02,"CYP51A1,HMGCS1,IDI1,Scd2,SLC25A20,TCAP"
HOXA10, ,transcription regulator, ,0.816, ,-0.045,0.927,1.79E-02,"ADM,CTSV,IGFBP5,PROM1,SCD,Scd2"
tert-butyl-hydroquinone, ,chemical reagent, ,-0.13, ,0.124,-0.372,1.83E-02,"JUN,MAF,MAP1A,SNTB2"
HDAC4,-0.145,transcription regulator, , , , , ,1.86E-02,"ANGPTL4,FGF13,GPM6A,JUN,Pcp4l1"
fish oils, ,chemical drug, , , , , ,1.88E-02,"CPT1A,CRH,FASN"
C2CD5,0.039,other, , , , , ,1.91E-02,"CPT1A,TNFRSF9"
CREBZF,0.011,transcription regulator, , , , , ,1.91E-02,"FASN,INSIG1"
G6PD,0.091,enzyme, , , , , ,1.91E-02,"FASN,NMRAL1"
PLIN1, ,other, , , , , ,1.91E-02,"ACACA,FASN"
RHOJ,-0.035,enzyme, , , , , ,1.91E-02,"AKAP12,PLAT"
Srebp, ,group, , , , , ,1.91E-02,"FASN,LDLR"
N-acetyl-L-cysteine, ,chemical drug, ,-0.956, ,-0.084,-0.734,1.91E-02,"ADM,BNIP3,CCN1,CCN2,FASN,HDC,JUN"
ionomycin, ,chemical reagent, ,0.577, ,0.107,0.319,1.97E-02,"FGF18,ITPR3,LDLR,MAF,Sik1,STAT5B"
ARNTL,0.066,transcription regulator, , , , , ,1.99E-02,"ACACA,FASN,SCD"
CD28, ,transmembrane receptor, ,0.647, ,0.09,0.396,2.02E-02,"CASP6,FDPS,IGFBP5,JUN,MAF,MSLN,NFATC2,ORAI3,TFRC"
sphingosine-1-phosphate, ,chemical - endogenous mammalian, ,-0.48, ,0.07,-0.617,2.04E-02,"ANXA2,CCN2,JUN,VWF"
PDX1, ,transcription regulator, ,-1.342, ,0.036,-1.422,2.06E-02,"ANXA2,CPT2,ECH1,INSIG1,JUN,RHOBTB1"
FOXM1,-0.118,transcription regulator, ,1.387, ,0.126,1.107,2.09E-02,"CTNNAL1,JUN,Nes,PECAM1,PROM1"
miR-30c-5p (and other miRNAs w/seed GUAAACA), ,mature microrna, ,-0.585, ,-0.144,-0.265,2.09E-02,"CCN2,COL4A5,JUN,LOXL2,NID1"
CCN5, ,growth factor, , , , , ,2.09E-02,"CCN2,JUN,SDC4"
1-methyl-4-phenylpyridinium, ,chemical toxicant, , , , , ,2.11E-02,"DDIT4,TFRC"
MPZ, ,other, , , , , ,2.11E-02,"HMGCS1,JUN"
NONO,0.004,transcription regulator, , , , , ,2.11E-02,"ACACA,FASN"
finasteride, ,chemical drug, , , , , ,2.11E-02,"CLU,CRH"
Hbb-b1, ,transporter, , , , , ,2.11E-02,"NDUFA11,NDUFS8,PECAM1,TFRC"
decitabine, ,chemical drug,Activated,2.186, ,0.056,1.974,2.15E-02,"AKAP12,ANGPTL4,ANXA2,BNIP3,CCN2,CLU,LDLR,MAF,NDRG1,PSAT1,PXDN,SHC1,STAT5B,TFRC,TIMP3,TNFRSF9"
levodopa, ,chemical - endogenous mammalian, ,-0.535, ,0.016,-0.595,2.16E-02,"CHRM2,Cox5b,DGAT2,ECE1,EDNRB,FAM114A1,FDPS,IGFBP5,INSC,PCYT2,ROBO2,SH3PXD2B,SHC1,VAMP1"
gentamicin, ,chemical drug, ,0.378, ,0.035,0.284,2.16E-02,"CLU,CTSV,JUN,MAF,PSAT1,TFRC,YBX3"
camptothecin, ,chemical drug, , , , , ,2.17E-02,"ANXA2,BNIP3L,DUSP10,INSIG1,JUN,LDLR,LY75,PECAM1,SDC4,SNTB2,STAT5B,TFRC,TUBB2A"
KMT2A,0.066,transcription regulator, ,1, ,0.14,0.719,2.19E-02,"DUSP10,PROM1,RSPO1,SLC16A6"
SOCS3,0.176,phosphatase, , , , , ,2.19E-02,"CRH,FASN,JUN,SCD"
desmopressin, ,biologic drug, ,1.98, ,0.068,1.844,2.19E-02,"ADM,CRH,PXN,VWF"
CD3 group, ,group, , , , , ,2.20E-02,"FASN,SCD,TFRC"
SFRP1,0.239,transmembrane receptor, , , , , ,2.20E-02,"ACACA,FASN,SCD"
ERK, ,group, ,-1.23, ,0.092,-1.469,2.20E-02,"CCN2,CLU,HEY1,JUN,LDLR,NDRG1,PECAM1"
ERN1,0.172,kinase, ,-0.447, ,0.076,-0.616,2.20E-02,"ACACA,DGAT2,FASN,JUN,SCD"
quercetin, ,chemical drug, ,0.391, ,0.01,0.368,2.20E-02,"CRH,ECH1,FASN,JUN,LDLR"
"5,6-epoxyeicosatrienoic acid", ,chemical - endogenous mammalian, , , , , ,2.24E-02,PLAT
ACPP, ,phosphatase, , , , , ,2.24E-02,SHC1
ATP1A1,0.048,transporter, , , , , ,2.24E-02,LDLR
B4GALNT2, ,enzyme, , , , , ,2.24E-02,VWF
CREB5,0.136,transcription regulator, , , , , ,2.24E-02,CRH
CRHBP, ,other, , , , , ,2.24E-02,CRH
CYP4A22-AS1, ,other, , , , , ,2.24E-02,TAL1
Chorf, ,other, , , , , ,2.24E-02,FASN
Cop9 Signalosome, ,complex, , , , , ,2.24E-02,JUN
DPP10-AS1, ,other, , , , , ,2.24E-02,TIMP3
DUSP2,0.224,phosphatase, , , , , ,2.24E-02,HDC
FRAT1, ,other, , , , , ,2.24E-02,JUN
HSD17B13, ,enzyme, , , , , ,2.24E-02,FASN
IL17RC,-0.078,transmembrane receptor, , , , , ,2.24E-02,STEAP4
IPO9,-0.045,transporter, , , , , ,2.24E-02,PXN
KCNAB2,-0.024,ion channel, , , , , ,2.24E-02,KCNA4
KLHL40,-0.159,other, , , , , ,2.24E-02,BNIP3
LY3039478, ,chemical drug, , , , , ,2.24E-02,PROM1
MARCHF2,0.122,enzyme, , , , , ,2.24E-02,TFRC
MARK4,-0.03,kinase, , , , , ,2.24E-02,CCN2
MDC1,-0.1,other, , , , , ,2.24E-02,CLU
MYL2,-0.099,other, , , , , ,2.24E-02,MYL7
N(6)-carboxymethyl-L-lysine, ,chemical - endogenous mammalian, , , , , ,2.24E-02,CCN2
N-methylscopolamine, ,chemical drug, , , , , ,2.24E-02,CHRM2
NMB, ,other, , , , , ,2.24E-02,JUN
NUBP1,-0.197,other, , , , , ,2.24E-02,TFRC
ORC, ,complex, , , , , ,2.24E-02,CDT1
PACS1,0.099,other, , , , , ,2.24E-02,IGF2R
Pde3, ,group, , , , , ,2.24E-02,CRH
RILP,-0.141,other, , , , , ,2.24E-02,IGF2R
Rab11, ,group, , , , , ,2.24E-02,ITGA6
SB 559457, ,chemical reagent, , , , , ,2.24E-02,DDIT4
SLC9A9,0.103,transporter, , , , , ,2.24E-02,TFRC
STK26,0.264,kinase, , , , , ,2.24E-02,CCN2
TAN 67, ,chemical reagent, , , , , ,2.24E-02,MAPK3
TJP1,0.045,other, , , , , ,2.24E-02,YBX3
TJP2,0.029,kinase, , , , , ,2.24E-02,YBX3
VANGL1,0.029,other, , , , , ,2.24E-02,JUN
VANGL2,0.106,other, , , , , ,2.24E-02,SDC4
VPS33B,0.023,transporter, , , , , ,2.24E-02,VWF
alirocumab, ,biologic drug, , , , , ,2.24E-02,LDLR
amsacrine, ,chemical drug, , , , , ,2.24E-02,JUN
clusterin antisense oligonucleotide, ,biologic drug, , , , , ,2.24E-02,CLU
enalaprilat, ,chemical - endogenous mammalian, , , , , ,2.24E-02,LDLR
fascaplysin, ,chemical - endogenous non-mammalian, , , , , ,2.24E-02,CPT1A
histidyl-proline diketopiperazine, ,chemical - endogenous mammalian, , , , , ,2.24E-02,FGB
loganin, ,chemical - endogenous non-mammalian, , , , , ,2.24E-02,CCN2
masitinib, ,chemical drug, , , , , ,2.24E-02,DHCR24
methoxamine, ,chemical drug, , , , , ,2.24E-02,CRH
miR-378a-5p (miRNAs w/seed UCCUGAC), ,mature microrna, , , , , ,2.24E-02,TUSC2
pyridoxal, ,chemical - endogenous mammalian, , , , , ,2.24E-02,MAPK3
ristocetin, ,chemical toxicant, , , , , ,2.24E-02,VWF
silvestrol, ,chemical - endogenous non-mammalian, , , , , ,2.24E-02,JUN
BRD4, ,kinase, ,0, ,0.136,-0.298,2.26E-02,"BDH1,FADS1,LOXL2,PLAT,SLC16A6"
DSCAM, ,other, ,0, ,0.074,-0.147,2.27E-02,"NEURL1B,PRKCH,ROBO2,TAL1"
TAF4,-0.159,transcription regulator, , , , , ,2.27E-02,"CARMIL1,CCN2,GAS1,ITGA6"
okadaic acid, ,chemical toxicant, ,-0.152, ,0.043,-0.237,2.27E-02,"BNIP3,CCN2,JUN,NDRG1"
JAG1,0.189,growth factor, , , , , ,2.31E-02,"DUSP10,HEY1,TIMP3"
salirasib, ,chemical drug, , , , , ,2.31E-02,"ADM,BNIP3,PLAT"
Mir200, ,group, , , , , ,2.31E-02,"JUN,LOXL2"
SPZ1, ,transcription regulator, , , , , ,2.31E-02,"MAPK3,PROM1"
mangiferin, ,chemical - endogenous non-mammalian, , , , , ,2.31E-02,"ACACA,DGAT2"
Pka, ,complex, ,-0.229, ,0.071,-0.377,2.32E-02,"CCN2,CYP51A1,JUN,LDLR,NTS"
IFNG, ,cytokine, ,1.681, ,0.056,1.439,2.34E-02,"Acot1,ADM,ANGPTL4,CASP6,CCN2,CTSV,ECE1,EDNRB,FABP5,FASN,FGF12,FGG,Gvin1 (includes others),HMGCS1,IDI1,ITGA6,JUN,MMP11,PECAM1,PROM1,SDC4,TFRC,TIMP3,UBE2C,UBE2L6"
3-methylcholanthrene, ,chemical toxicant, , , , , ,2.42E-02,"ADM,CCN1,Mt2"
colchicine, ,chemical drug, , , , , ,2.42E-02,"CCN2,CRH,JUN"
PC-SPES, ,chemical drug, , , , , ,2.42E-02,"CLU,SELENBP1,TUBB2A,UBE2C"
olanzapine, ,chemical drug, ,-1, ,0.043,-1.086,2.42E-02,"GRIP1,HMGCS1,LDLR,YBX3"
ACOX1,0.094,enzyme, ,-0.447, ,-0.026,-0.388,2.45E-02,"ACOT2,ANXA2,CTSV,FASN,SELENBP1"
CYP27A1,0.123,enzyme, , , , , ,2.52E-02,"ACACA,HMGCS1"
EIF4G2,-0.046,translation regulator, , , , , ,2.52E-02,"JUN,PLAT"
EPCAM, ,other, , , , , ,2.52E-02,"FABP5,JUN"
ETS, ,group, , , , , ,2.52E-02,"CRH,VWF"
HFE,-0.016,transmembrane receptor, , , , , ,2.52E-02,"HEPH,TFRC"
MAP3K5,-0.116,kinase, , , , , ,2.52E-02,"CCN2,JUN"
OXT, ,other, , , , , ,2.52E-02,"CRH,MYL7"
cuprizone, ,chemical toxicant, , , , , ,2.52E-02,"FDPS,HMGCS1"
mezerein, ,chemical - endogenous non-mammalian, , , , , ,2.52E-02,"INSIG1,SLC16A6"
telmisartan, ,chemical drug, , , , , ,2.54E-02,"CCN1,CCN2,CPT1A"
cocaine, ,chemical drug,Activated,2.4, ,0.098,2.166,2.57E-02,"Acot1,CPT1A,CPT2,JUN,NTS,Sik1"
ETV5,-0.075,transcription regulator, , , , , ,2.59E-02,"FASN,MAF,SCD,TIMP3"
N-nitro-L-arginine methyl ester, ,chemical drug, ,-0.218, ,0.002,-0.221,2.59E-02,"ADM,CCN2,INSIG1,LDLR"
NFAT5,-0.063,transcription regulator, , , , , ,2.59E-02,"DDIT4,HSPA2,PLAT,VWF"
POMC, ,other, , , , , ,2.59E-02,"CRH,JUN,LDLR,Sik1"
CDX2, ,transcription regulator, ,1.964, ,0.056,1.854,2.65E-02,"CLU,HEPH,JUN,NTS,TAL1"
GNRH1, ,other, , , , , ,2.66E-02,"IGFBP5,JUN,PLAT"
S-nitroso-N-acetyl-DL-penicillamine, ,chemical reagent, , , , , ,2.66E-02,"ADM,BNIP3,LDLR"
hexachlorobenzene, ,chemical toxicant, , , , , ,2.66E-02,"ANXA2,CLU,FGB"
cigarette smoke, ,chemical toxicant, ,-0.2, ,0.082,-0.381,2.66E-02,"ADM,CCN1,CHRM2,DDIT4,FABP5,JUN,VEGFB"
Pdgf (complex), ,complex, ,-1.228, ,0.083,-1.387,2.67E-02,"HEY1,JUN,LDLR,TIMP3"
prostaglandin E2, ,chemical - endogenous mammalian, ,1.436, ,0.048,1.307,2.71E-02,"ANGPTL4,ANXA2,CASP6,CCN2,FASN,HDC,IGFBP5,JUN"
HMGA1,-0.059,transcription regulator, ,0.447, ,0.043,0.351,2.71E-02,"CCN1,IDI1,INSIG1,MVK,SDC4"
BRD7,-0.023,transcription regulator, , , , , ,2.74E-02,"FASN,NDRG1"
JUN/JUNB/JUND, ,group, , , , , ,2.74E-02,"CCN1,JUN"
PDGF-DD, ,complex, , , , , ,2.74E-02,"CLU,VEGFB"
miR-18a-5p (and other miRNAs w/seed AAGGUGC), ,mature microrna, , , , , ,2.74E-02,"CCN2,FGG"
mir-33, ,microrna, , , , , ,2.74E-02,"ACACA,CPT1A"
P38 MAPK, ,group, ,-0.329, ,0.116,-0.649,2.75E-02,"BNIP3,BNIP3L,CCN2,EDNRB,IGFBP5,JUN,Nes,NFATC2,TIMP3"
CEBPD,0.189,transcription regulator, , , , , ,2.76E-02,"CLU,CRH,CTSV,IGFBP5"
MKNK1,-0.015,kinase, ,1, ,0.144,0.712,2.76E-02,"ANXA2,CCN1,FLNB,HSPA2"
torin1, ,chemical reagent, ,1.067, ,-0.133,1.33,2.76E-02,"ALDH9A1,FASN,NDUFS8,NTS"
PTK2,0.01,kinase, , , , , ,2.78E-02,"CCN1,LDLR,TIMP3"
benzene, ,chemical toxicant, , , , , ,2.78E-02,"BNIP3,DHCR24,ECE1"
trichloroethylene, ,chemical toxicant, , , , , ,2.78E-02,"BNIP3,DHCR24,ECE1"
PTGER2, ,g-protein coupled receptor, ,0.152, ,0.097,-0.041,2.85E-02,"ECT2,HDC,PXN,TIMP3"
KLF5, ,transcription regulator, , , , , ,2.90E-02,"CDT1,FAM110A,FGF18"
ZAP70, ,kinase, , , , , ,2.90E-02,"COL4A5,SCD,UBE2L6"
IL15,-0.086,cytokine, ,1.146, ,0.086,0.922,2.95E-02,"CCN2,CPT1A,JUN,MAF,MAPK3,MSLN,NAGA,TFRC,TNFRSF9,TNNI2"
COL4A3,0.118,other, , , , , ,2.97E-02,"CCN2,COL4A5"
IPMK,0.12,kinase, , , , , ,2.97E-02,"CCN1,JUN"
JINK1/2, ,group, , , , , ,2.97E-02,"FASN,SCD"
LCAT, ,enzyme, , , , , ,2.97E-02,"CLU,LDLR"
MAP3K3,0.033,kinase, , , , , ,2.97E-02,"JUN,STEAP4"
NFAT (complex), ,complex, , , , , ,2.97E-02,"CYGB,IL33"
Ni2+, ,chemical reagent, , , , , ,2.97E-02,"ANGPTL4,NDRG1"
bisindolylmaleimide iv, ,chemical - kinase inhibitor, , , , , ,2.97E-02,"CCN2,PRKCH"
paroxetine, ,chemical drug, , , , , ,2.97E-02,"ADM,BNIP3"
risperidone, ,chemical drug, , , , , ,2.97E-02,"FADS2,NTS"
DIO2,-0.129,enzyme, ,1, ,-0.011,1.021,2.99E-02,"CARMIL1,DDIT4,NTS,SLN,Xlr3c (includes others)"
IFNAR1,0.045,transmembrane receptor,Activated,2, ,0.088,1.823,2.99E-02,"HMGCS1,IDI1,PLAT,RIPOR2,VEGFB"
RBPJ,0.067,transcription regulator, ,1.964, ,-0.061,2.084,2.99E-02,"ECT2,FGF13,FGF18,HEY1,JUN"
puromycin aminonucleoside, ,chemical reagent, ,1.154, ,0.076,1.004,3.03E-02,"ANXA2,CLU,CTSV,FGB"
PTGES, ,enzyme, , , , , ,3.03E-02,"ANXA2,CCN2,ITGA6"
phenylbutazone, ,chemical drug, , , , , ,3.03E-02,"ANXA2,CLU,FGB"
"1,2-dithiol-3-thione", ,chemical reagent, ,-0.106, ,0.107,-0.366,3.10E-02,"BNIP3,EPB41,NAT8B,PSAT1,TFRC,Xlr3c (includes others)"
KDM1A,0.052,enzyme, ,0.701, ,-0.029,0.771,3.10E-02,"ADM,FASN,PROM1,PSAT1,SCD,ZNF367"
INHA,-0.131,growth factor, ,-0.152, ,-0.003,-0.147,3.12E-02,"CCN1,CCN2,COL4A5,CYP51A1"
mir-10, ,microrna, , , , , ,3.12E-02,"CCN1,HDC,MAF,PROM1"
cyclic AMP, ,chemical - endogenous mammalian, ,1.132, ,0.092,0.893,3.18E-02,"CCN2,CRH,IGFBP5,IL33,ITPR3,JUN,VWF"
GW7647, ,chemical drug, , , , , ,3.21E-02,"CPT1A,IGFBP5"
HSD17B4,0.061,enzyme, , , , , ,3.21E-02,"ACOT2,FASN"
LRPAP1,0.025,other, , , , , ,3.21E-02,"LDLR,MAPK3"
SIRT2,0.069,transcription regulator, , , , , ,3.21E-02,"IDI1,MVK"
Smad, ,complex, , , , , ,3.21E-02,"ANGPTL4,CCN2"
dibutyl phthalate, ,chemical toxicant, , , , , ,3.21E-02,"FGB,JUN"
CD44,0.124,other, , , , , ,3.23E-02,"CLU,FASN,JUN,PECAM1,PMEPA1,SDC4"
RHO, ,g-protein coupled receptor, , , , , ,3.30E-02,"EPB41,H1-2,NID1"
(Ala9)-autocamtide-2, ,chemical - kinase inhibitor, , , , , ,3.35E-02,CRH
17alpha-hydroxyprogesterone caproate, ,chemical drug, , , , , ,3.35E-02,CRH
"3,4-methylenedioxyamphetamine", ,chemical drug, , , , , ,3.35E-02,JUN
BR-4628, ,chemical reagent, , , , , ,3.35E-02,CCN2
BTG1,-0.061,transcription regulator, , , , , ,3.35E-02,JUN
C1QL1, ,other, , , , , ,3.35E-02,CRH
CDC20,-0.095,other, , , , , ,3.35E-02,UBE2C
CNDP2,-0.105,peptidase, , , , , ,3.35E-02,MMP11
CNPY2,0.131,other, , , , , ,3.35E-02,LDLR
CRYAA/CRYAA2, ,other, , , , , ,3.35E-02,CASP6
DDOST,0.023,enzyme, , , , , ,3.35E-02,PROM1
DLST,-0.037,enzyme, , , , , ,3.35E-02,JUN
DUB, ,group, , , , , ,3.35E-02,LDLR
Defb2, ,other, , , , , ,3.35E-02,TNFRSF9
EMP2,-0.027,other, , , , , ,3.35E-02,ITGA6
Eotaxin, ,group, , , , , ,3.35E-02,MAPK3
FTL,0.024,enzyme, , , , , ,3.35E-02,TFRC
FTMT, ,enzyme, , , , , ,3.35E-02,TFRC
GBP1, ,enzyme, , , , , ,3.35E-02,VWF
GLUD1,-0.033,enzyme, , , , , ,3.35E-02,MAPK3
GPC3,0.145,other, , , , , ,3.35E-02,LDLR
IRS, ,group, , , , , ,3.35E-02,DGAT2
KLHL2,0.15,other, , , , , ,3.35E-02,JUN
LIFR,-0.007,transmembrane receptor, , , , , ,3.35E-02,FGB
LSS,-0.138,enzyme, , , , , ,3.35E-02,LDLR
MAPK15, ,kinase, , , , , ,3.35E-02,JUN
MTCH2,0.023,other, , , , , ,3.35E-02,SHC1
MYLIP,0.134,enzyme, , , , , ,3.35E-02,LDLR
"N(1)-guanyl-1,7-diaminoheptane", ,chemical reagent, , , , , ,3.35E-02,MVK
PARD6A,-0.044,other, , , , , ,3.35E-02,ECT2
PDCD5,-0.167,other, , , , , ,3.35E-02,NFATC2
PIGT,-0.136,enzyme, , , , , ,3.35E-02,PIGK
PRAG1,0.109,kinase, , , , , ,3.35E-02,HEY1
PRR7, ,other, , , , , ,3.35E-02,JUN
REG3G, ,other, , , , , ,3.35E-02,IL33
RING1,0.026,transcription regulator, , , , , ,3.35E-02,JUN
Rbpjl2, ,other, , , , , ,3.35E-02,HEY1
S100A2, ,other, , , , , ,3.35E-02,BNIP3
SLC3A2,-0.007,transporter, , , , , ,3.35E-02,CCN2
SPRED2,-0.3,cytokine, , , , , ,3.35E-02,CRH
STRAP,-0.049,other, , , , , ,3.35E-02,JUN
TOP2B,-0.014,enzyme, , , , , ,3.35E-02,FASN
TRAF7,0.067,enzyme, , , , , ,3.35E-02,JUN
TUBB1, ,other, , , , , ,3.35E-02,TUBB2A
UPP1,-0.114,enzyme, , , , , ,3.35E-02,Acot1
ZHX2,-0.083,transcription regulator, , , , , ,3.35E-02,HDC
apitolisib, ,chemical drug, , , , , ,3.35E-02,NDRG1
capivasertib, ,chemical drug, , , , , ,3.35E-02,PROM1
compound 48/80, ,chemical reagent, , , , , ,3.35E-02,LDLR
defibrotide, ,biologic drug, , , , , ,3.35E-02,PLAT
"ergosterol-5,8-peroxide", ,chemical - endogenous mammalian, , , , , ,3.35E-02,CCN2
ethyl ether, ,chemical reagent, , , , , ,3.35E-02,CRH
miR-139-3p (miRNAs w/seed GGAGACG), ,mature microrna, , , , , ,3.35E-02,MMP11
mir-329, ,microrna, , , , , ,3.35E-02,DDIT4
mir-497, ,microrna, , , , , ,3.35E-02,MAPK3
nickel subsulfide, ,chemical toxicant, , , , , ,3.35E-02,NDRG1
pirenzepine, ,chemical drug, , , , , ,3.35E-02,CHRM2
potassium channel, ,group, , , , , ,3.35E-02,JUN
sangivamycin, ,chemical - endogenous non-mammalian, , , , , ,3.35E-02,JUN
stavudine, ,chemical drug, , , , , ,3.35E-02,CPT1A
sulfurbutylether-beta-cyclodextrin, ,chemical reagent, , , , , ,3.35E-02,LDLR
thioguanine, ,chemical drug, , , , , ,3.35E-02,BNIP3
FN1,0.164,enzyme, ,0.447, ,0.084,0.26,3.36E-02,"BNIP3L,CCN1,CCN2,DHCR24,PXN,SDC4"
medroxyprogesterone acetate, ,chemical drug, ,1.706, ,-0.017,1.741,3.37E-02,"CCN1,FASN,JUN,SCD,SPC25"
GLI1, ,transcription regulator, ,1.091, ,0.119,0.857,3.42E-02,"CLU,INSIG1,MMP11,SALL1,TIMP3,TNFRSF9"
SIM1, ,transcription regulator, ,0.816, ,0.137,0.48,3.42E-02,"ANGPTL4,CRH,Gypa,NFATC2,SELENBP1,TNFRSF9"
IL6ST,0.069,transmembrane receptor, , , , , ,3.43E-02,"FGB,JUN,MAF"
PPP3R1,0.007,phosphatase, , , , , ,3.43E-02,"ARID3A,SCD,Scd2"
USF2,0.025,transcription regulator, , , , , ,3.43E-02,"CPT1A,FASN,IGF2R"
ADAMTS12,-0.075,peptidase, , , , , ,3.45E-02,"HDC,IL33"
K-252, ,chemical - kinase inhibitor, , , , , ,3.45E-02,"JUN,NDRG1"
KAT2A,0.033,enzyme, , , , , ,3.45E-02,"BNIP3,JUN"
PROX1,-0.032,transcription regulator, , , , , ,3.45E-02,"HEY1,TNNI2"
STS, ,enzyme, , , , , ,3.45E-02,"ACACA,EEF1A2"
arotinoid acid, ,chemical toxicant, , , , , ,3.45E-02,"ALDH9A1,SCD"
dasatinib, ,chemical drug, , , , , ,3.45E-02,"CCN1,CCN2"
diazoxide, ,chemical drug, , , , , ,3.45E-02,"ACACA,FASN"
linolenic acid, ,chemical - endogenous mammalian, , , , , ,3.45E-02,"CLU,FASN"
thyroid hormone receptor, ,group, , , , , ,3.45E-02,"CPT1A,MMP11"
SMAD3,-0.03,transcription regulator, ,-0.7, ,0.079,-0.871,3.47E-02,"ARID3A,CCN2,CYP51A1,HEY1,JUN,PMEPA1,TIMP3"
MECP2,-0.099,transcription regulator, , , , , ,3.53E-02,"CAMK1D,CLU,CRH,ITGA6,PROM1"
GnRH analog, ,biologic drug, ,-0.137, ,-0.006,-0.122,3.53E-02,"ACACA,EDNRB,HSPA2,ITPR3,JUN,MAPK3,NDRG1,VEGFB"
gentamicin C, ,chemical drug, , , , , ,3.57E-02,"ANXA2,CLU,FGB"
NR5A2,-0.102,ligand-dependent nuclear receptor, ,1.091, ,0.075,0.944,3.61E-02,"FASN,FGB,JUN,LDLR"
RAF1,-0.054,kinase, ,0.896, ,0.126,0.589,3.70E-02,"AKAP12,HDC,JUN,PLAT,SELENBP1,TUBB2A"
ATOH1, ,transcription regulator, , , , , ,3.70E-02,"CRH,SALL1"
TRIB3,0.391,kinase, , , , , ,3.70E-02,"DDIT4,PSAT1"
ceramide, ,chemical - endogenous mammalian, , , , , ,3.70E-02,"JUN,NAT8B"
p70 S6k, ,group, , , , , ,3.70E-02,"FASN,SCD"
NRG2, ,growth factor, , , , , ,3.72E-02,"BNIP3,CCN1,CCN2"
folic acid, ,chemical - endogenous mammalian, , , , , ,3.72E-02,"CLU,JUN,PECAM1"
lomustine, ,chemical drug, , , , , ,3.72E-02,"ANXA2,CLU,FGB"
ursodeoxycholic acid, ,chemical - endogenous mammalian, , , , , ,3.72E-02,"CCN2,FASN,MAF"
methylmercury, ,chemical toxicant, , , , , ,3.86E-02,"BNIP3,DHCR24,ECE1"
triamterene, ,chemical drug, , , , , ,3.86E-02,"ANXA2,CLU,FGB"
EIF4E,-0.061,translation regulator, ,0, ,0.144,-0.288,3.86E-02,"BNIP3,CDT1,INSIG1,TUSC2,UBE2C"
GNA15, ,enzyme, , , , , ,3.93E-02,"ADM,AKAP12,PLAT,SELENBP1"
KIT,0.032,transmembrane receptor, , , , , ,3.93E-02,"EML1,Gypa,HDC,SHC1"
PSMB11,-0.251,peptidase, ,0, ,-0.113,0.227,3.93E-02,"CTSV,LY75,NID1,ROBO2"
Pkc(s), ,group, ,0.305, ,0.083,0.111,3.98E-02,"ADM,CCN1,CCN2,CPT1A,JUN,MAPK3"
Tcf7, ,transcription regulator, ,0.509, ,-0.006,0.523,3.98E-02,"DHCR24,FDPS,LDLR,MAF,PECAM1,VEGFB"
MAF,0.453,transcription regulator, , , , , ,4.01E-02,"CYP51A1,IDI1,MAF"
Rxr, ,group, , , , , ,4.03E-02,"ANGPTL4,CPT1A,INSIG1,MMP11"
Hdac, ,group, ,-0.094, ,-0.01,-0.073,4.12E-02,"CRH,DKK3,EDNRB,JUN,ROBO2"
melatonin, ,chemical - endogenous mammalian, , , , , ,4.14E-02,"ACACA,ECE1,FASN,PLAT"
KCNE3,0.199,ion channel, , , , , ,4.16E-02,"EPN3,FABP5,Sik1"
Pro-inflammatory Cytokine, ,group, , , , , ,4.16E-02,"ADM,CLU,SDC4"
calphostin C, ,chemical - kinase inhibitor, , , , , ,4.16E-02,"CLU,ECE1,LDLR"
miR-21-5p (and other miRNAs w/seed AGCUUAU), ,mature microrna, , , , , ,4.16E-02,"FGF18,PECAM1,TIMP3"
GRP, ,growth factor, , , , , ,4.22E-02,"IL33,JUN"
calcimycin, ,chemical reagent, ,0.121, ,0.093,-0.059,4.26E-02,"CRH,DDIT4,JUN,SHC1"
dextran sulfate, ,chemical drug, , , , , ,4.28E-02,"CCN2,IL33,NFATC2,PECAM1,SPC25,UBE2C,VEGFB"
androgen, ,chemical drug, , , , , ,4.30E-02,"CTSV,DHCR24,IGFBP5,JUN,SDC4"
COLQ,-0.35,other, , , , , ,4.31E-02,"NID1,SDC4,SNTB2"
Raf, ,group, , , , , ,4.31E-02,"JUN,SLC16A6,SPRED2"
fenamic acid, ,chemical reagent, , , , , ,4.31E-02,"ANXA2,CLU,FGB"
13(S)-hydroxyoctadecadienoic acid, ,chemical - endogenous mammalian, , , , , ,4.44E-02,MAPK3
4-methylcatechol, ,chemical - endogenous mammalian, , , , , ,4.44E-02,JUN
ABI1,0.052,other, , , , , ,4.44E-02,PXN
ACSL3,-0.055,enzyme, , , , , ,4.44E-02,SCD
BOK,-0.275,other, , , , , ,4.44E-02,ITPR3
CFL1,0.012,other, , , , , ,4.44E-02,JUN
CMIP,0.108,other, , , , , ,4.44E-02,MAF
Co2+, ,chemical - endogenous mammalian, , , , , ,4.44E-02,NDRG1
DLL3, ,other, , , , , ,4.44E-02,HEY1
FDX2,-0.147,transporter, , , , , ,4.44E-02,TFRC
FDXR,0.076,enzyme, , , , , ,4.44E-02,TFRC
GCLC,-0.11,enzyme, , , , , ,4.44E-02,JUN
GIT1,-0.053,kinase, , , , , ,4.44E-02,PXN
GLRX3,0.005,enzyme, , , , , ,4.44E-02,TFRC
HSPBP1,-0.271,other, , , , , ,4.44E-02,HSPA2
ITPR, ,group, , , , , ,4.44E-02,MAPK3
MIR129, ,group, , , , , ,4.44E-02,MAPK3
MLK4B, ,other, , , , , ,4.44E-02,JUN
N-docosahexaenoylethanolamine, ,chemical - endogenous mammalian, , , , , ,4.44E-02,JUN
NBN,-0.037,other, , , , , ,4.44E-02,CLU
NT157, ,chemical reagent, , , , , ,4.44E-02,PECAM1
PF-4691502, ,chemical drug, , , , , ,4.44E-02,PROM1
PHLDA1,-0.308,other, , , , , ,4.44E-02,ITGA6
PLAGL2,0.113,transcription regulator, , , , , ,4.44E-02,BNIP3
RAB11FIP3,-0.151,other, , , , , ,4.44E-02,JUN
RNF139,0.009,enzyme, , , , , ,4.44E-02,FASN
SPRED1,-0.102,other, , , , , ,4.44E-02,CRH
TBX20,-0.029,transcription regulator, , , , , ,4.44E-02,BMP10
TIAM1,0.145,other, , , , , ,4.44E-02,JUN
TXLNG,-0.021,other, , , , , ,4.44E-02,SCD
bisindolylmaleimide II, ,chemical - kinase inhibitor, , , , , ,4.44E-02,JUN
cholesterol ester, ,chemical - endogenous mammalian, , , , , ,4.44E-02,LDLR
clomiphene, ,chemical drug, , , , , ,4.44E-02,LDLR
diamide, ,chemical reagent, , , , , ,4.44E-02,SDC4
ethyl linoleate, ,chemical - endogenous mammalian, , , , , ,4.44E-02,FADS2
firtecan pegol, ,chemical drug, , , , , ,4.44E-02,BNIP3
mianserin, ,chemical drug, , , , , ,4.44E-02,CRH
nitrendipine, ,chemical drug, , , , , ,4.44E-02,LDLR
proanthocyanidin derivative, ,chemical - other, , , , , ,4.44E-02,JUN
pyridostigmine, ,chemical drug, , , , , ,4.44E-02,CHRM2
trimetazidine, ,chemical drug, , , , , ,4.44E-02,CCN2
tylophorine, ,chemical drug, , , , , ,4.44E-02,JUN
NCOA4,0.116,transcription regulator, , , , , ,4.48E-02,"CCN2,FABP5"
PRKCI,0.109,kinase, , , , , ,4.48E-02,"ECT2,FASN"
PTX3,-0.08,other, , , , , ,4.48E-02,"CCN2,JUN"
leucine, ,chemical - endogenous mammalian, , , , , ,4.48E-02,"ACACA,FASN"
tosedostat, ,chemical drug, , , , , ,4.48E-02,"DDIT4,PSAT1"
CDKN1B,-0.034,kinase, ,-1, ,-0.105,-0.791,4.48E-02,"CSDC2,EPB41,NFATC2,TENM4"
Histone h3, ,group, , , , , ,4.55E-02,"AKAP12,CRH,DUSP10,FASN,IGF2R,JUN,Nes,RSPO1,SCD,SLC16A6"
SMARCB1,-0.027,transcription regulator, , , , , ,4.58E-02,"BNIP3,BNIP3L,CDT1,HEY1,KLHL4"
ID1,0.123,transcription regulator, , , , , ,4.63E-02,"CCN2,PROM1,SCD"
IL1, ,group, ,-1.596, ,0.093,-1.853,4.64E-02,"ACACA,CPT1A,CRH,IL33,JUN,LDLR,NFATC2,SDC4"
STAT5A,0.099,transcription regulator, , , , , ,4.70E-02,"CASP6,FASN,H1-2,MAF,SELENBP1,STAT5B,TNFRSF9"
NGF,-0.245,growth factor, ,-0.198, ,0.09,-0.383,4.76E-02,"ADM,ANXA2,CRH,JUN,LDLR,SHC1"
epigallocatechin-gallate, ,chemical drug, ,1.004, ,-0.049,1.109,4.76E-02,"CASP6,CCN1,CCN2,JUN,LDLR,TFRC"
ACKR3,0.073,g-protein coupled receptor, , , , , ,4.76E-02,"ADM,VWF"
DRD2, ,g-protein coupled receptor, , , , , ,4.76E-02,"EDNRB,JUN"
HISTONE, ,group, , , , , ,4.76E-02,"DKK3,NFATC2"
IFRD1,-0.008,other, , , , , ,4.76E-02,"CCN2,DGAT2"
Rhox5,-0.328,transcription regulator, , , , , ,4.76E-02,"SCD,TFRC"
TG,0.118,other, , , , , ,4.76E-02,"ACACA,CPT1A"
UPF2,0.067,other, , , , , ,4.76E-02,"CLU,HEY1"
Akt, ,group, ,0.152, ,0.046,0.062,4.77E-02,"ADM,CCN2,CPT1A,FASN,JUN,NDRG1,SCD"
EGFR,-0.063,kinase, ,-0.578, ,0.065,-0.763,4.78E-02,"CCN2,FASN,HDC,IGFBP5,IL33,ITGA6,JUN,PLAT,PROM1"
FGF7, ,growth factor, , , , , ,4.79E-02,"FABP5,FASN,SCD"
HIPK2,-0.148,kinase, , , , , ,4.79E-02,"EPB41,Gypa,PECAM1"
KDM3B,0.077,enzyme, , , , , ,4.79E-02,"CCN2,FADS2,KIF26B"
MEF2D,-0.118,transcription regulator, , , , , ,4.79E-02,"CCN2,CDT1,JUN"
silibinin, ,chemical drug, , , , , ,4.79E-02,"CCN2,PECAM1,PROM1"
MLXIPL,0.174,transcription regulator, ,-1.326, ,0.139,-1.597,4.84E-02,"ACACA,CPT1A,FASN,SCD"
salmonella minnesota R595 lipopolysaccharides, ,chemical - endogenous non-mammalian, ,0.068, ,0.144,-0.216,4.84E-02,"EDNRB,JUN,Nes,SLFN13"
ATG7,0.101,enzyme, , , , , ,4.96E-02,"ACACA,CCN2,PECAM1"
KDM8,-0.149,enzyme, , , , , ,4.96E-02,"ACACA,DHCR24,FASN"
PAX7, ,transcription regulator, , , , , ,4.96E-02,"CAMK1D,Marcks,MSLN"
TRAF3IP2,-0.145,other, , , , , ,4.96E-02,"CCN2,IL33,STEAP4"
phenylephrine, ,chemical drug, , , , , ,4.96E-02,"BNIP3L,EDNRB,JUN"
CSF3, ,cytokine, ,-0.749, ,0.04,-0.817,4.96E-02,"FGB,HDC,JUN,TAL1,TFRC"
GATA1, ,transcription regulator,Activated,2, ,0.056,1.889,4.99E-02,"Gypa,ITGA6,PECAM1,RANGRF,TAL1,TFRC,VWF"
TSC2,0.047,other, ,-1.982, ,-0.071,-1.841,6.13E-02,"ANXA2,IGFBP5,NSDHL,SCD"
IKBKG,0.078,kinase, ,1.982, ,0.103,1.778,7.13E-02,"CLU,CTSF,Mt2,NID1"
CST5, ,other,Inhibited,-2.425, ,-0.07,-2.256,9.46E-02,"AGO1,AKAP12,ANXA2,ANXA3,EPN3,ITPR3"
EGLN, ,group, ,-1.944, ,-0.139,-1.674,1.11E-01,"ADM,BNIP3,NTS,SELENBP1"
SATB1,0.043,transcription regulator, ,1.982, ,-0.024,2.031,1.21E-01,"FAM110A,MAF,RIPOR2,UBE2L6"
glucocorticoid, ,chemical drug,Inhibited,-2.087, ,-0.007,-2.073,1.24E-01,"CCN2,CLU,CPT2,CRH,FASN,PLAT"
trichostatin A, ,chemical drug,Activated,2.531, ,0.036,2.399,1.38E-01,"AKAP12,CLU,FASN,HMGCS1,LDLR,MAF,MVK,NDRG1,Nes,PSAT1,SHC1,STAT5B,TIMP3,VWF"
IL33,0.665,cytokine,Activated,2, ,0.103,1.793,1.46E-01,"DGAT2,HDC,Marcks,PLAT,TNFRSF9"
TLR3,-0.024,transmembrane receptor,Activated,2.191, ,0.125,1.916,1.77E-01,"CLU,IL33,Marcks,NTS,PECAM1"
RELA,-0.022,transcription regulator, ,1.941, ,0.096,1.755,3.78E-01,"BNIP3L,CCN2,JUN,PECAM1,PXN,SDC4"