Concentration_TopoVI_pM,Negative_Supercoil_Average,Positive_Supercoil_Average,fit_Negative_Supercoil_Average,fit_Positive_Supercoil_Average,Negative_Supercoil_SE,Positive_Supercoil_SE 250,,2.50779,0,0,,0.751604 500,1.66028,3.47618,0.0452889,0.137862,0.285195,0.761337 1000,2.85079,4.9109,0.0900382,0.271229,0.587031,0.865889 1500,3.38883,6.28026,0.134257,0.400318,0.689002,1.32448 2000,4.02,6.376,0.177956,0.52533,0.52,0.59 ,,,0.221143,0.646456,, ,,,0.263827,0.763874,, ,,,0.306018,0.877752,, ,,,0.347723,0.988248,, ,,,0.38895,1.09551,, ,,,0.42971,1.19968,, ,,,0.470008,1.30088,, ,,,0.509852,1.39925,, ,,,0.549252,1.4949,, ,,,0.588213,1.58794,, ,,,0.626743,1.67848,, ,,,0.66485,1.76662,, ,,,0.702539,1.85244,, ,,,0.739819,1.93605,, ,,,0.776695,2.01752,, ,,,0.813175,2.09693,, ,,,0.849263,2.17437,, ,,,0.884968,2.24991,, ,,,0.920295,2.32361,, ,,,0.955249,2.39554,, ,,,0.989837,2.46577,, ,,,1.02406,2.53435,, ,,,1.05794,2.60134,, ,,,1.09146,2.6668,, ,,,1.12464,2.73078,, ,,,1.15748,2.79332,, ,,,1.18999,2.85448,, ,,,1.22216,2.9143,, ,,,1.25402,2.97282,, ,,,1.28555,3.03009,, ,,,1.31677,3.08615,, ,,,1.34769,3.14103,, ,,,1.37829,3.19477,, ,,,1.4086,3.24741,, ,,,1.43861,3.29897,, ,,,1.46833,3.3495,, ,,,1.49776,3.39902,, ,,,1.52691,3.44757,, ,,,1.55578,3.49516,, ,,,1.58438,3.54183,, ,,,1.6127,3.58761,, ,,,1.64075,3.63252,, ,,,1.66855,3.67659,, ,,,1.69608,3.71983,, ,,,1.72335,3.76228,, ,,,1.75038,3.80395,, ,,,1.77715,3.84486,, ,,,1.80368,3.88504,, ,,,1.82997,3.9245,, ,,,1.85601,3.96327,, ,,,1.88182,4.00136,, ,,,1.9074,4.03879,, ,,,1.93275,4.07557,, ,,,1.95787,4.11173,, ,,,1.98277,4.14728,, ,,,2.00745,4.18223,, ,,,2.03191,4.2166,, ,,,2.05615,4.2504,, ,,,2.08019,4.28366,, ,,,2.10401,4.31637,, ,,,2.12763,4.34855,, ,,,2.15105,4.38023,, ,,,2.17426,4.4114,, ,,,2.19727,4.44208,, ,,,2.22009,4.47228,, ,,,2.24272,4.50202,, ,,,2.26515,4.5313,, ,,,2.2874,4.56013,, ,,,2.30946,4.58853,, ,,,2.33133,4.6165,, ,,,2.35303,4.64406,, ,,,2.37454,4.67121,, ,,,2.39588,4.69796,, ,,,2.41704,4.72432,, ,,,2.43803,4.7503,, ,,,2.45885,4.7759,, ,,,2.4795,4.80115,, ,,,2.49998,4.82603,, ,,,2.5203,4.85057,, ,,,2.54046,4.87476,, ,,,2.56045,4.89862,, ,,,2.58029,4.92215,, ,,,2.59997,4.94535,, ,,,2.61949,4.96825,, ,,,2.63886,4.99083,, ,,,2.65808,5.01311,, ,,,2.67715,5.0351,, ,,,2.69608,5.05679,, ,,,2.71485,5.0782,, ,,,2.73348,5.09933,, ,,,2.75197,5.12019,, ,,,2.77032,5.14078,, ,,,2.78853,5.1611,, ,,,2.8066,5.18117,, ,,,2.82453,5.20098,, ,,,2.84233,5.22054,, ,,,2.86,5.23986,, ,,,2.87753,5.25894,, ,,,2.89493,5.27779,, ,,,2.9122,5.2964,, ,,,2.92935,5.31479,, ,,,2.94637,5.33296,, ,,,2.96327,5.35091,, ,,,2.98004,5.36864,, ,,,2.99669,5.38616,, ,,,3.01322,5.40348,, ,,,3.02963,5.42059,, ,,,3.04592,5.4375,, ,,,3.06209,5.45422,, ,,,3.07815,5.47074,, ,,,3.0941,5.48707,, ,,,3.10993,5.50322,, ,,,3.12565,5.51919,, ,,,3.14126,5.53497,, ,,,3.15676,5.55058,, ,,,3.17215,5.56601,, ,,,3.18743,5.58127,, ,,,3.20261,5.59636,, ,,,3.21768,5.61129,, ,,,3.23265,5.62606,, ,,,3.24751,5.64066,, ,,,3.26228,5.65511,, ,,,3.27694,5.6694,, ,,,3.2915,5.68354,, ,,,3.30597,5.69753,, ,,,3.32033,5.71137,, ,,,3.3346,5.72507,, ,,,3.34878,5.73862,, ,,,3.36286,5.75203,, ,,,3.37684,5.76531,, ,,,3.39073,5.77844,, ,,,3.40453,5.79145,, ,,,3.41824,5.80432,, ,,,3.43186,5.81706,, ,,,3.44539,5.82967,, ,,,3.45883,5.84215,, ,,,3.47218,5.85451,, ,,,3.48545,5.86675,, ,,,3.49863,5.87887,, ,,,3.51172,5.89086,, ,,,3.52474,5.90274,, ,,,3.53766,5.91451,, ,,,3.55051,5.92616,, ,,,3.56327,5.93769,, ,,,3.57595,5.94912,, ,,,3.58856,5.96044,, ,,,3.60108,5.97165,, ,,,3.61352,5.98275,, ,,,3.62589,5.99375,, ,,,3.63817,6.00465,, ,,,3.65039,6.01544,, ,,,3.66252,6.02613,, ,,,3.67458,6.03673,, ,,,3.68657,6.04723,, ,,,3.69848,6.05763,, ,,,3.71032,6.06794,, ,,,3.72209,6.07815,, ,,,3.73378,6.08827,, ,,,3.7454,6.0983,, ,,,3.75696,6.10824,, ,,,3.76844,6.11809,, ,,,3.77985,6.12786,, ,,,3.7912,6.13753,, ,,,3.80248,6.14713,, ,,,3.81369,6.15663,, ,,,3.82483,6.16606,, ,,,3.83591,6.1754,, ,,,3.84692,6.18467,, ,,,3.85787,6.19385,, ,,,3.86875,6.20295,, ,,,3.87957,6.21198,, ,,,3.89032,6.22093,, ,,,3.90101,6.22981,, ,,,3.91164,6.23861,, ,,,3.92221,6.24733,, ,,,3.93272,6.25598,, ,,,3.94317,6.26457,, ,,,3.95355,6.27307,, ,,,3.96388,6.28151,, ,,,3.97415,6.28988,, ,,,3.98436,6.29819,, ,,,3.99451,6.30642,, ,,,4.0046,6.31459,, ,,,4.01464,6.32269,, ,,,4.02462,6.33072,, ,,,4.03455,6.3387,, ,,,4.04442,6.3466,, ,,,4.05423,6.35445,, ,,,4.06399,6.36223,, ,,,4.07369,6.36995,, ,,,4.08334,6.37761,, ,,,4.09294,6.38521,, ,,,4.10249,6.39275,, ,,,4.11198,6.40024,, ,,,4.12142,6.40766,,