serum,virus,ic50,NT50,ic50_bound,date,replicate,top,ic50_is_bound,wildtype_ic50,fold_change participant A (day 120),wildtype,0.0007602408792174835,1315.37257116363,interpolated,2021-03-08,1,True,False,0.0007190255892275876,1.0573210336424483 participant A (day 120),wildtype,0.0006800447227939462,1470.4915228097436,interpolated,2021-03-08,2,True,False,0.0007190255892275876,0.9457865380347359 participant A (day 120),wildtype,0.0007194996164299146,1389.8548062636926,interpolated,2021-03-08,average,True,False,0.0007190255892275876,1.0006592633272429 participant A (day 120),G446V,0.0007818209149375109,1279.0652960210557,interpolated,2021-03-08,1,True,False,0.0007190255892275876,1.0873339233689598 participant A (day 120),G446V,0.0008111591728262715,1232.8036635716787,interpolated,2021-03-08,2,True,False,0.0007190255892275876,1.1281367241709135 participant A (day 120),G446V,0.000801189684445804,1248.143878302323,interpolated,2021-03-08,average,True,False,0.0007190255892275876,1.114271447983487 participant A (day 120),K417N,0.0006228142060903421,1605.6152705273157,interpolated,2021-03-08,1,True,False,0.0007190255892275876,0.8661919901340362 participant A (day 120),K417N,0.00045405277536864384,2202.387154638805,interpolated,2021-03-08,2,True,False,0.0007190255892275876,0.6314834717585079 participant A (day 120),K417N,0.0005567718510373073,1796.0678115047047,interpolated,2021-03-08,average,True,False,0.0007190255892275876,0.7743421922374402 participant B (day 113),wildtype,0.002340018721513421,427.3470082979695,interpolated,2021-03-08,1,True,False,0.0025406883036951725,0.9210176305806982 participant B (day 113),wildtype,0.002758566415382595,362.5071321189512,interpolated,2021-03-08,2,True,False,0.0025406883036951725,1.0857555456017731 participant B (day 113),wildtype,0.0025726684548628767,388.70146602442793,interpolated,2021-03-08,average,True,False,0.0025406883036951725,1.0125871997447276 participant B (day 113),G446V,0.00381882943381805,261.86034682366113,interpolated,2021-03-08,1,True,False,0.0025406883036951725,1.5030688448732383 participant B (day 113),G446V,0.00197667798350238,505.89929586211537,interpolated,2021-03-08,2,True,False,0.0025406883036951725,0.7780088492663594 participant B (day 113),G446V,0.0031295785412014114,319.5318432929026,interpolated,2021-03-08,average,True,False,0.0025406883036951725,1.2317837401186749 participant B (day 113),K417N,0.0021194377553988334,471.8232453171625,interpolated,2021-03-08,1,True,False,0.0025406883036951725,0.8341982573448018 participant B (day 113),K417N,0.0017337654605509136,576.7792834460115,interpolated,2021-03-08,2,True,False,0.0025406883036951725,0.6823999063676282 participant B (day 113),K417N,0.002021771344178212,494.61577486472356,interpolated,2021-03-08,average,True,False,0.0025406883036951725,0.7957573312860736 K041,B.1.351-K484Q,0.0011369032232740046,879.5823422157634,interpolated,2021-08-27,1,True,False,0.000513715109899854,2.2131006103667805 K041,B.1.351-K484Q,0.0013795725466108088,724.8622063817496,interpolated,2021-08-27,2,True,False,0.000513715109899854,2.6854817388566774 K041,B.1.351-K484Q,0.0013930715411961372,717.838223255474,interpolated,2021-08-27,average,True,False,0.000513715109899854,2.711758938660981 K041,wildtype,0.0004813740625992693,2077.3865434300988,interpolated,2021-08-27,1,True,False,0.000513715109899854,0.9370447808963818 K041,wildtype,0.0005482289858211814,1824.0553233465387,interpolated,2021-08-27,2,True,False,0.000513715109899854,1.067184856462672 K041,wildtype,0.0005270344831829327,1897.4090536935548,interpolated,2021-08-27,average,True,False,0.000513715109899854,1.0259275482196255 K046,B.1.351-K484Q,0.001413087650142136,707.6701858511144,interpolated,2021-08-27,1,True,False,0.0004806402301701417,2.9400111797589594 K046,B.1.351-K484Q,0.0014370366018506267,695.8764993961827,interpolated,2021-08-27,2,True,False,0.0004806402301701417,2.9898383690061285 K046,B.1.351-K484Q,0.001429285811183818,699.6501274799206,interpolated,2021-08-27,average,True,False,0.0004806402301701417,2.9737123974783914 K046,wildtype,0.0005027291043721411,1989.1428431399472,interpolated,2021-08-27,1,True,False,0.0004806402301701417,1.045957189630548 K046,wildtype,0.0004595218952889581,2176.1748683839683,interpolated,2021-08-27,2,True,False,0.0004806402301701417,0.956062073968074 K046,wildtype,0.0004810210612390556,2078.9110510548408,interpolated,2021-08-27,average,True,False,0.0004806402301701417,1.000792341225326 K114,B.1.351-K484Q,0.002106804357746618,474.6525211622277,interpolated,2021-08-27,1,True,False,0.0008202954376125162,2.5683482574016354 K114,B.1.351-K484Q,0.0020451128888947516,488.97056266680414,interpolated,2021-08-27,2,True,False,0.0008202954376125162,2.493141854899361 K114,B.1.351-K484Q,0.002077063843486547,481.44885056657955,interpolated,2021-08-27,average,True,False,0.0008202954376125162,2.5320924001867873 K114,wildtype,0.0009888695608220115,1011.2557202880591,interpolated,2021-08-27,1,True,False,0.0008202954376125162,1.205504157989874 K114,wildtype,0.0006804584058675705,1469.5975409768369,interpolated,2021-08-27,2,True,False,0.0008202954376125162,0.829528453611855 K114,wildtype,0.0008350575250892265,1197.522290327423,interpolated,2021-08-27,average,True,False,0.0008202954376125162,1.0179960619062756 K119,B.1.351-K484Q,0.001471922550592064,679.38357191264,interpolated,2021-08-27,1,True,False,0.00026638213610985685,5.525605328072895 K119,B.1.351-K484Q,0.0014748610065221236,678.0299944047639,interpolated,2021-08-27,2,True,False,0.00026638213610985685,5.53663630775108 K119,B.1.351-K484Q,0.001473895779334584,678.4740237545611,interpolated,2021-08-27,average,True,False,0.00026638213610985685,5.5330128395950124 K119,wildtype,0.00028605481079737514,3495.833533484402,interpolated,2021-08-27,1,True,False,0.00026638213610985685,1.0738513286769547 K119,wildtype,0.0002480623983936905,4031.243777676202,interpolated,2021-08-27,2,True,False,0.00026638213610985685,0.9312276041340428 K119,wildtype,0.0002667875717719056,3748.3005424816656,interpolated,2021-08-27,average,True,False,0.00026638213610985685,1.0015220076990505 K007,B.1.351-K484Q,0.0014841992680222488,673.7639760007007,interpolated,2021-08-27,1,True,False,0.000526264550184977,2.8202531739988315 K007,B.1.351-K484Q,0.0014459938403829193,691.5658781334685,interpolated,2021-08-27,2,True,False,0.000526264550184977,2.74765579379167 K007,B.1.351-K484Q,0.0014647285563299862,682.7203550298719,interpolated,2021-08-27,average,True,False,0.000526264550184977,2.7832552198607106 K007,wildtype,0.000541133927074717,1847.9713615552425,interpolated,2021-08-27,1,True,False,0.000526264550184977,1.028254566803927 K007,wildtype,0.0005118037567494007,1953.873895633868,interpolated,2021-08-27,2,True,False,0.000526264550184977,0.9725218173435898 K007,wildtype,0.0005331356471528403,1875.6952481800904,interpolated,2021-08-27,average,True,False,0.000526264550184977,1.0130563553358252 K031,B.1.351-K484Q,0.001420733232665894,703.8619052526693,interpolated,2021-08-27,1,True,False,0.0004485737580369598,3.167223243025362 K031,B.1.351-K484Q,0.001447302507613533,690.9405564762732,interpolated,2021-08-27,2,True,False,0.0004485737580369598,3.226453803154227 K031,B.1.351-K484Q,0.0014303039182435803,699.1521083351324,interpolated,2021-08-27,average,True,False,0.0004485737580369598,3.188559055489224 K031,wildtype,0.00041536427289818326,2407.5253103078667,interpolated,2021-08-27,1,True,False,0.0004485737580369598,0.9259665003942555 K031,wildtype,0.00048443843038162564,2064.2458097559083,interpolated,2021-08-27,2,True,False,0.0004485737580369598,1.0799526760138982 K031,wildtype,0.0004479237955908445,2232.5226072906585,interpolated,2021-08-27,average,True,False,0.0004485737580369598,0.9985510466573887 K033,B.1.351-K484Q,0.0007107978710477082,1406.869717443035,interpolated,2021-08-27,1,True,False,0.00026892443994229074,2.6431136984062897 K033,B.1.351-K484Q,0.0006949761980001581,1438.8981995031902,interpolated,2021-08-27,2,True,False,0.00026892443994229074,2.5842805441903867 K033,B.1.351-K484Q,0.0007029591821594382,1422.5577037461471,interpolated,2021-08-27,average,True,False,0.00026892443994229074,2.613965403480205 K033,wildtype,0.00024451016579546116,4089.8095044298684,interpolated,2021-08-27,1,True,False,0.00026892443994229074,0.9092151157698098 K033,wildtype,0.00029577647278180083,3380.9315210061227,interpolated,2021-08-27,2,True,False,0.00026892443994229074,1.0998497304494614 K033,wildtype,0.0002677822998324937,3734.3767703299723,interpolated,2021-08-27,average,True,False,0.00026892443994229074,0.9957529330170134 K040,B.1.351-K484Q,0.001118967946215213,893.6806486569976,interpolated,2021-08-27,1,True,False,0.00036036830183398924,3.105067622542139 K040,B.1.351-K484Q,0.0009007507388193741,1110.1850455440238,interpolated,2021-08-27,2,True,False,0.00036036830183398924,2.4995282166474304 K040,B.1.351-K484Q,0.0010057878989332496,994.2454080632822,interpolated,2021-08-27,average,True,False,0.00036036830183398924,2.7909999126299008 K040,wildtype,0.0003390683480862284,2949.2578875150275,interpolated,2021-08-27,1,True,False,0.00036036830183398924,0.9408939309052406 K040,wildtype,0.00038300629858168653,2610.9231198105813,interpolated,2021-08-27,2,True,False,0.00036036830183398924,1.0628190565942892 K040,wildtype,0.0003638835194087906,2748.1321540055496,interpolated,2021-08-27,average,True,False,0.00036036830183398924,1.0097545138041046 pre-pandemic,wildtype,0.04,25.0,lower,2021-06-10,1,True,True,0.04000000000000001,0.9999999999999998 pre-pandemic,wildtype,0.04,25.0,lower,2021-06-10,2,True,True,0.04000000000000001,0.9999999999999998 pre-pandemic,wildtype,0.04,25.0,lower,2021-06-10,average,True,True,0.04000000000000001,0.9999999999999998 K006,wildtype,0.04,25.0,lower,2021-06-10,1,True,True,0.04000000000000001,0.9999999999999998 K006,wildtype,0.04,25.0,lower,2021-06-10,2,True,True,0.04000000000000001,0.9999999999999998 K006,wildtype,0.04,25.0,lower,2021-06-10,average,True,True,0.04000000000000001,0.9999999999999998 K119,wildtype,0.00015949811138418293,6269.666714681662,interpolated,2021-06-10,1,True,False,0.00019661227994480928,0.8112316861843797 K119,wildtype,0.0002423626730725632,4126.047907140391,interpolated,2021-06-10,2,True,False,0.00019661227994480928,1.2326934672676417 K119,wildtype,0.00019678240518068073,5081.755145140261,interpolated,2021-06-10,average,True,False,0.00019661227994480928,1.0008652828598459 K119,RBD antibodies depleted,0.007640257632011622,130.88563870021062,interpolated,2021-06-10,1,True,False,0.00019661227994480928,38.859513933495435 K119,RBD antibodies depleted,0.008364234009917731,119.55667414544703,interpolated,2021-06-10,2,True,False,0.00019661227994480928,42.54176805368231 K119,RBD antibodies depleted,0.007950872555513966,125.77235932507753,interpolated,2021-06-10,average,True,False,0.00019661227994480928,40.439348741318916 K116,wildtype,0.04,25.0,lower,2021-06-10,1,True,True,0.04000000000000001,0.9999999999999998 K116,wildtype,0.04,25.0,lower,2021-06-10,2,True,True,0.04000000000000001,0.9999999999999998 K116,wildtype,0.04,25.0,lower,2021-06-10,average,True,True,0.04000000000000001,0.9999999999999998 K116,RBD antibodies depleted,0.04,25.0,lower,2021-06-10,1,True,True,0.04000000000000001,0.9999999999999998 K116,RBD antibodies depleted,0.04,25.0,lower,2021-06-10,2,True,True,0.04000000000000001,0.9999999999999998 K116,RBD antibodies depleted,0.04,25.0,lower,2021-06-10,average,True,True,0.04000000000000001,0.9999999999999998 REGN10987 (spike-in),wildtype,0.00544585894222615,183.62576236527005,interpolated,2021-06-10,1,True,False,0.006571696562667393,0.8286838703361746 REGN10987 (spike-in),wildtype,0.0079302817369927,126.098924750083,interpolated,2021-06-10,2,True,False,0.006571696562667393,1.2067327913530246 REGN10987 (spike-in),wildtype,0.006938293285961098,144.12766350240545,interpolated,2021-06-10,average,True,False,0.006571696562667393,1.0557841829423886 REGN10987 (spike-in),RBD antibodies depleted,0.25,4.0,lower,2021-06-10,1,True,True,0.006571696562667393,38.04192686257066 REGN10987 (spike-in),RBD antibodies depleted,0.25,4.0,lower,2021-06-10,2,True,True,0.006571696562667393,38.04192686257066 REGN10987 (spike-in),RBD antibodies depleted,0.25,4.0,lower,2021-06-10,average,True,True,0.006571696562667393,38.04192686257066 K114,wildtype,0.0009897378029175396,1010.3686017167472,interpolated,2021-06-10,1,True,False,0.0008753574400249566,1.130667036872757 K114,wildtype,0.0007741955955893559,1291.6632511177627,interpolated,2021-06-10,2,True,False,0.0008753574400249566,0.8844336726803664 K114,wildtype,0.0008786739722710318,1138.0785496756976,interpolated,2021-06-10,average,True,False,0.0008753574400249566,1.003788774841487 K114,RBD antibodies depleted,0.021708940556234596,46.06397062121071,interpolated,2021-06-10,1,True,False,0.0008753574400249566,24.80008687150208 K114,RBD antibodies depleted,0.022944237384256612,43.58392842841483,interpolated,2021-06-10,2,True,False,0.0008753574400249566,26.211278199226214 K114,RBD antibodies depleted,0.02232739669006733,44.7880249489572,interpolated,2021-06-10,average,True,False,0.0008753574400249566,25.506605266793382 K115,wildtype,0.004145760299241858,241.21027937453877,interpolated,2021-06-10,1,True,False,0.0038667515742986354,1.0721558444037953 K115,wildtype,0.0036065200730672317,277.2755952386899,interpolated,2021-06-10,2,True,False,0.0038667515742986354,0.9327002275085113 K115,wildtype,0.0038631462400937275,258.856366766933,interpolated,2021-06-10,average,True,False,0.0038667515742986354,0.9990676064557983 K115,RBD antibodies depleted,0.018499486543098607,54.05555433499632,interpolated,2021-06-10,1,True,False,0.0038667515742986354,4.784244911429074 K115,RBD antibodies depleted,0.019027203429243297,52.55633092475795,interpolated,2021-06-10,2,True,False,0.0038667515742986354,4.9207204196185055 K115,RBD antibodies depleted,0.01877344188549199,53.2667374528053,interpolated,2021-06-10,average,True,False,0.0038667515742986354,4.855093875250359 K041,wildtype,0.0004636707501735635,2156.702788833833,interpolated,2021-06-10,1,True,False,0.0004011120490159667,1.1559631562080215 K041,wildtype,0.00034699380067766125,2881.8958668628975,interpolated,2021-06-10,2,True,False,0.0004011120490159667,0.865079474747588 K041,wildtype,0.00040662076061376794,2459.294007739704,interpolated,2021-06-10,average,True,False,0.0004011120490159667,1.013733597909401 K041,RBD antibodies depleted,0.010299964423161133,97.08771398776277,interpolated,2021-06-10,1,True,False,0.0004011120490159667,25.67852162115213 K041,RBD antibodies depleted,0.009878937835048085,101.22545730090957,interpolated,2021-06-10,2,True,False,0.0004011120490159667,24.628873301821066 K041,RBD antibodies depleted,0.010180062141968708,98.23122747722357,interpolated,2021-06-10,average,True,False,0.0004011120490159667,25.379596965344412 K046,wildtype,0.0006960022766014039,1436.7769095282624,interpolated,2021-06-10,1,True,False,0.000598015162052901,1.1638538966338698 K046,wildtype,0.0005138232245323036,1946.194629310943,interpolated,2021-06-10,2,True,False,0.000598015162052901,0.8592143763854106 K046,wildtype,0.0005940233352605794,1683.4355498194886,interpolated,2021-06-10,average,True,False,0.000598015162052901,0.9933248736058495 K046,RBD 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