Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR GOTERM_BP_DIRECT,GO:0006412~translation,195,5.243344985,1.56E-43,"RPL4, EIF4A2, EIF4A1, RPL5, RPL3, VARS, RPL32, RPL31, RPL34, RPL8, EPRS, RPL9, RPL6, RPL7, RPS15, RPS14, RPS17, RPS16, RPL18A, RPS19, RPS18, RPL36AL, RPL36, AKT1, RPL35, RPL38, DENR, RPL37, RPS11, RPL39, RPS13, RPS12, EIF2A, RPL21, RPL23, RPL22, MRPS18B, AARSD1, LARS2, KARS, RPL24, RPL27, EIF1A, RPL29, UBA52, EIF1B, RPL28, MRPL18, MRPL19, MRPL14, MRPL15, MRPL12, MRPL13, GSPT1, MRPL10, MRPL11, MRPL20, GM6525, MCTS1, RPL41, MRPL27, MRPL23, MRPL24, EIF1, MRPL30, RPS26, AIMP1, RPS28, EIF5, EIF6, RPS29, RPL27A, RPS20, FARSA, RPS21, RPS24, FARSB, RPS23, MRPS17, MRPS15, MRPS16, MRPS14, MRPS12, MRPL36, MRPL37, MRPL34, MRPL33, RARS, WARS, MRPS24, MRPS23, MRPS21, MRPS7, MRPL43, MRPS5, MRPL52, MRPS9, MRPL51, GM4832, GARS, RPL10, RPL12, RPL11, RPS27L, EGFR, RPS15A, UCP2, RPL14, RPS3, RPL13, RPS2, RPL15, RPL18, RPS27A, RPL17, RPL19, RPL34-PS1, RSL1D1, MARS, RPL22L1, FAU, RPL10A, NARS, EEF1B2, SLC25A45, SLC25A44, RPS9, RPS7, RPS8, EIF1AX, RPS5, RPS6, SARS, RPSA, TUFM, EEF1A1, NHP2, SLC25A51, TARS, EIF2S3X, EIF2B2, EIF2S2, EEF2, EIF2S1, IARS, EIF4G2, EIF4G1, SLC25A1, SLC25A3, MRPL4, RPS4X, RBM3, RPL7A, MRPL3, MRPL2, MRPL1, MRPL9, EIF2B1, EIF5A, EIF5B, TSFM, GM10653, RPL13A, EEF1G, SLC25A15, EEF1D, RPL37A, ETF1, SLC25A10, EIF4E2, SLC25A5, SLC25A11, SLC25A4, RPL36A, RRBP1, SLC25A28, EIF4H, EIF4B, RPL35A, RPL23A, EIF3M, SLC25A39, EIF3K, RPS3A1, EIF3L, EIF3I, EIF3G, EIF3H, EIF3E, EIF3F, EIF3C, EIF3D, EIF3A, SLC25A35, EIF3B",3331,401,18082,2.639745578,1.04E-39,1.04E-39,1.02E-39 GOTERM_BP_DIRECT,GO:0006810~transport,529,14.22425383,9.23E-32,"PGAP1, ATP5C1, SLC4A2, SLC4A4, SCAMP5, SCAMP4, SCP2, AKT1, AP1S1, VPS35, ATG3, GABARAPL2, STARD4, STARD5, NUP210, CACNA2D1, SCAMP1, SCAMP2, RBP4, RBP2, DDX39B, ZC3H11A, FDX1, UQCRC1, UQCRC2, VPS25, TTYH3, TTYH2, SAR1A, TTYH1, MRPL18, AGAP1, ABCB9, SLC5A1, SLC30A10, A230046K03RIK, OAZ1, GABARAP, NUP85, MYO6, S100A13, NUP88, SLC19A1, VTI1B, BTF3, PRELID1, STARD10, SLC16A10, EHD1, SLC6A6, FAM160A2, SLC6A8, TCN2, FXYD3, FXYD6, SFXN1, E430025E21RIK, ARF3, ARF4, ARF1, SRPR, TSPO, AP3S1, SLC18A1, SLC18A2, EXOC8, PLLP, SLC39A11, TMC6, DYNLL1, TMC5, SLC39A14, TMC4, DYNLL2, COPZ1, VAMP8, SLC7A5, SLC7A9, PLIN3, HAP1, SLC29A1, ERGIC3, ARF5, ERGIC1, PAFAH1B1, ARF6, VAMP3, ATP5A1, USO1, TIMM13, AFP, SLC7A1, LMAN1, TCOF1, ASNA1, LMAN2, UCP2, AP2S1, STX3, ABCB1A, LDLR, SLC17A4, LRRC26, TRAPPC10, TMCO3, LRPPRC, TMCO1, ARCN1, FABP1, FABP2, FABP5, SNX17, CRAT, RAB3B, MTCH1, RAB3C, MTCH2, CSE1L, RAB3D, GOLIM4, SLC8A1, ERO1L, IPO5, LAPTM4B, LAPTM4A, SLC39A9, MPC1, SLCO2B1, MPC2, KPNA6, CHP1, SLC39A5, SLC39A7, SLC25A45, SLC25A44, SLC16A3, SLC39A4, FADS1, RAB2A, SLC38A1, STX8, VPS33B, THOC3, THOC7, STIM2, SLCO2A1, SLC25A51, SRSF3, SRSF7, KPNB1, SLC27A4, ENY2, KCNE3, UQCRB, GPR89, ARL3, CUL3, ITPR1, ITPR3, UQCRH, BAG6, G3BP1, TPR, G3BP2, RAB6A, SLC38A2, AP1M2, MPDU1, SLC14A1, RAB4A, ANKRD27, SLC37A1, RAB4B, ATP8B1, TRAPPC4, GOT2, MOB4, MFSD7B, NACA, UQCRQ, ALB, RAB5A, SLC26A3, CNIH4, SLC25A1, SLC25A3, MCFD2, ARRB1, ETFA, ETFB, AP1G2, AP1G1, ERC1, TNPO2, SLC36A1, EIF5A, SLC13A1, AMN, PDCD6IP, SIGMAR1, APOA1, NDUFC2, APOA4, NDUFC1, ARFGAP3, SLC25A15, SMDT1, SLC25A10, SFT2D2, SLC25A5, SLC25A11, SLC25A4, ANK, NDUFB9, NDUFB8, SEC23A, NDUFB7, NDUFB6, NDUFB5, RAB1B, SRSF1, NDUFB3, NDUFB2, GLRX, SELENBP1, TTR, SLC25A28, RAB25, RAB24, IGF2BP2, SLC12A2, NDUFA9, SLC35A2, CYB5B, SLC35A1, NDUFA8, SLC35A4, NDUFA7, NDUFA6, MYO10, NDUFA5, TRPA1, NDUFA4, NDUFA3, TXNL1, NDUFA2, NDUFA1, APOC3, ATOX1, RAB10, P2RX4, SLC25A39, RAB14, RAB15, VPS41, RAB17, KCNK1, SLC25A35, SLC46A1, KDELR1, SLC35B1, PITPNB, PITPNA, GCC2, AQP1, NIPAL1, MAGOH, TRIM27, SEC62, ATP6V1E1, SLC12A7, SIL1, SLC12A8, SEC63, MFSD2A, CPT1A, SLC6A19, ATP6V1G1, SLC35C2, SLC35C1, SLC11A2, AP1B1, ACTN4, SLC51A, DOPEY2, KCNQ1, VDAC3, VDAC2, KDELR2, PREB, VDAC1, ZG16, ATP6V0D1, CFTR, TMEM63A, STXBP1, MTTP, STXBP2, ATP5K, ATP5J, PIK3R1, ATP5H, ATP5O, ATP5L, SEC14L2, SNX3, TRPM2, ATP5B, SNX1, SCFD1, SNX2, RAB11FIP1, ATP5E, ATP5D, KCNN4, APOB, SNX5, ATP6V1C1, TRPM4, SNX6, SEC31A, XBP1, MYO5B, RAB9, CLIC6, CLIC5, TRAM1, SLC35F5, ICA1, MIA3, MAGT1, AP2A2, XPO1, SERP1, XPO6, CHMP1B, SLC22A18, CHMP1A, TMED3, TMED2, SEC61B, TMED6, CLIC1, RAB8A, TMED4, ATP6V0B, SEC13, TMED9, TMED8, DBNL, ANO9, ANO6, AP3B1, ANO7, COMMD1, SORCS2, RAB33B, CLDN15, ATP6V0E, NAPA, DYNC1I2, CD63, TOMM40, STX17, SLC20A1, SYPL, STX16, DERL1, UQCR11, UQCR10, CUX1, BCAP31, DYNC1H1, RANBP3, MTX1, SLC31A1, SORT1, YIPF5, AP3D1, AP2B1, YIF1A, RAB11A, PLEKHA8, RAB11B, HNRNPA2B1, NDUFAB1, TOMM7, ESYT1, COPG1, APBA3, RAMP1, TOMM5, TOMM6, TXN1, NDUFA11, NDUFA12, ZFAND6, HDLBP, TOMM20, TXN2, TOMM22, DMBT1, KHSRP, TRAPPC11, TMEM38B, SLC30A7, ABCG8, RALBP1, ABCG5, ATG9A, SDHC, ATP1B3, CYBA, SDHD, SDHA, ATP1B1, SDHB, ATP5J2, SCG5, CHMP4B, PPID, ATP6V1A, COPB2, RTN3, VCP, COPA, PKDCC, TSG101, TMED10, NDUFB10, NDUFB11, COPB1, FAM21, CACNA1A, SLC1A4, SLC1A5, CPLX2, HIGD1A, CPLX1, CACNA1H, TIMM50, ATP6V1H, NDUFV3, CYC1, NDUFV2, ATP6V1D, NDUFV1, ATP6V1F, ACBD5, ALYREF, TIMM44, DNAJC15, IGF2R, HIGD2A, BSPRY, NASP, HOOK2, CHMP2B, SELK, CHMP2A, DYNLRB1, COPE, ABCD4, MCUR1, ABCD3, SLC2A1, ATP2A3, SLC40A1, SLC2A2, ATP2A2, DBI, ATP5G3, SLC2A5, ATP5G2, USE1, ATP5G1, SEC61A1, LASP1, CPT2, HEPH, NUP62, UQCRFS1, MFSD1, TIMM17B, GET4, ABCC3, JAGN1, ATP6AP1, NCBP2, ATP5F1, TRAPPC6A, LMBRD1, NDUFS8, RABEP1, NDUFS7, NDUFS6, TRAPPC6B, NDUFS4, PEX5, ATP6V1B2, NDUFS3, NDUFS2, STX5A, NDUFS1, TMEM9, CHMP6, CDH17, CHMP5, LTF, GOSR2, SLC3A2, RRBP1, ATP2C2, ATP1A1, CLCN3, CLCN2, CLN3, MVB12A, TIMM8B, ARFGEF1, TMEM30A, ATP13A1, SLC50A1, ATP2B1, SLC4A7, GOLPH3, RANGRF, AQP11, RAN",3331,1822,18082,1.57608317,6.16E-28,3.08E-28,3.02E-28 GOTERM_BP_DIRECT,GO:0055114~oxidation-reduction process,241,6.480236623,3.06E-27,"CYP3A11, CYP3A13, IFI30, ALKBH5, FTH1, ACAD11, MECR, JMJD6, POR, MTHFD1, MTHFD2, ETHE1, AKR1C13, FDX1, UQCRC1, UQCRC2, HPD, TSTA3, TPH1, MAOB, CTBP2, RETSAT, CTBP1, MAOA, MGST1, ADH5, PRDX3, PRDX2, ADH4, CYB5R1, ADH1, PRDX5, LDHA, PRDX4, CYB5R3, PRDX1, MICAL1, MARC2, DECR2, FDFT1, VAT1, MICAL2, PYCR2, CYP3A25, ACADSB, PRDX6, MSRA, GLUD1, ADI1, FASN, CYP2S1, OGDH, ALDH18A1, PAM, DHRS11, GDI1, HIBADH, TECR, GDI2, RDH7, AKR1B7, ACADL, AIFM1, SH3PXD2A, CYP2B10, 4833439L19RIK, SCD2, QSOX1, PHGDH, ACADM, SCD1, ACADS, VKORC1, CBR1, GSTO1, AKR1A1, PTGR1, UGDH, HADHA, BDH1, DPYD, DLD, PCYOX1, HSD17B4, NOXO1, UQCR11, UQCR10, FAM213B, CYP2C55, CREG1, SC5D, XDH, EGLN1, NQO1, EGLN3, MDH1, MDH2, GSR, DHRS1, FAM213A, FMO5, DHRS3, DHRS4, DHRS7, NDUFAB1, MSRB1, TXN1, KDM1A, NDUFA11, NDUFA12, CPOX, PLOD3, H2-KE6, TXN2, ERO1L, TM7SF2, AKR7A5, HADH, FADS1, PHYH, KDM2A, SDHC, CYBA, SDHD, PGD, SDHA, SDHB, CYP2D26, ALDH3A2, GPD2, GPD1, GLYR1, NDUFB10, UQCRB, NDUFB11, HIGD1A, UQCRH, ALDH3B1, CYC1, NDUFV3, NDUFV2, NDUFV1, PDHA1, CYP2J6, SRD5A1, IDH1, IDH2, DHCR24, CYP2C29, CYP51, CYP4F14, HIGD2A, QDPR, GRHPR, UQCRQ, DNAJC10, CRYL1, CYCS, DEGS1, DHCR7, DEGS2, KDM5A, ACADVL, PYCRL, SRXN1, ETFA, SQRDL, ETFB, SPR, HEPH, ALDH2, CYP4V3, UQCRFS1, ME2, LBR, IDH3A, KDM6B, GPX2, GPX1, GPX4, GPX3, DCXR, SORD, NDUFC2, NDUFC1, NDUFS8, NDUFS7, ASPH, ACOX1, NDUFS6, EHHADH, G6PDX, CAT, NDUFS4, ALDH1A1, NDUFS3, NDUFS2, NDUFS1, ALDH1A7, ALDH9A1, NDUFB9, NDUFB8, KDM3A, NDUFB7, NDUFB6, NDUFB5, NDUFB3, NDUFB2, SEPW1, HSD17B13, GLRX, HMGCR, HSD17B11, HSD17B10, ALDH1B1, BCO2, NDUFA9, CYB5B, HSD3B7, NDUFA8, RRM1, NDUFA7, NDUFA6, NDUFA5, IDH3G, NDUFA4, SMOX, NDUFA3, TXNRD1, NDUFA2, TXNL1, NDUFA1, CYP4B1, SOD2, SUOX, GFER, SOD1, IMPDH1, IMPDH2, ALDH16A1, CDO1",3331,676,18082,1.935272738,2.04E-23,6.82E-24,6.69E-24 GOTERM_BP_DIRECT,GO:0098609~cell-cell adhesion,93,2.500672224,1.56E-21,"LAD1, TES, YWHAB, ARHGAP1, HDLBP, OLA1, BZW2, CLINT1, BZW1, GOLGA2, RPL7A, LASP1, SLK, ATIC, CAPZB, PPME1, RARS, BSG, EFHD2, ERC1, TMPO, SH3GL1, MKL2, NUDC, DBNL, ARHGEF16, AHSA1, YWHAZ, SND1, HCFC1, EEF1G, PLCB3, GPRC5A, EEF1D, PLIN3, TAGLN2, PKP3, ALDOA, PLEC, DDX6, LRRC59, TXNDC9, PDXDC1, USO1, TWF1, SLC3A2, NDRG1, GIGYF2, IGSF9, FAM129B, CNN3, PSMB6, PDLIM1, CCNB2, LIMA1, LDHA, LARP1, PUF60, EPCAM, PRDX1, MYO6, STK38, PACSIN2, RPL14, EIF4H, EIF2S3X, FLNB, RPS2, RPL15, PDLIM5, ARGLU1, MARK2, SNX5, VASP, IDH1, CGN, PRDX6, PAICS, RPS26, RAB10, MYO1B, EIF5, STK24, VAPA, GLOD4, CAPZA1, ABI1, SERBP1, UBAP2, EIF3E, PFKP, EIF4G2, EIF4G1",3331,189,18082,2.671117401,1.04E-17,2.60E-18,2.55E-18 GOTERM_BP_DIRECT,GO:0015031~protein transport,198,5.324011831,6.10E-19,"PGAP1, KDELR1, GCC2, SCAMP5, SCAMP4, AP1S1, VPS35, SEC62, SIL1, SEC63, GABARAPL2, ATG3, NUP210, AP1B1, ACTN4, SCAMP1, SCAMP2, DOPEY2, PREB, KDELR2, ZG16, VPS25, SAR1A, STXBP1, STXBP2, AGAP1, ABCB9, PIK3R1, A230046K03RIK, GABARAP, SNX3, SNX1, SCFD1, SNX2, RAB11FIP1, NUP85, MYO6, S100A13, NUP88, SNX5, SEC31A, VTI1B, SNX6, BTF3, XBP1, EHD1, FAM160A2, MYO5B, PPT1, E430025E21RIK, MON1A, RAB9, ARF3, ARF4, ARF1, TRAM1, GDI1, GDI2, MIA3, AP2A2, XPO1, SERP1, XPO6, CHMP1B, CHMP1A, TMED3, AP3S1, SEC61B, RAB8A, TMED4, SEC13, TMED9, EXOC8, AP3B1, COMMD1, COPZ1, RAB33B, VAMP8, HAP1, ARF5, ARF6, VAMP3, NAPA, CD63, TOMM40, STX16, USO1, DERL1, TIMM13, LMAN1, LMAN2, AP2S1, BCAP31, RANBP3, MTX1, YIPF5, AP3D1, AP2B1, RAB11A, YIF1A, ARCN1, KTN1, RAB11B, SNX17, TOMM7, COPG1, APBA3, RAMP1, TOMM5, TOMM6, RAB3B, RAB3C, GOLT1A, ZFAND6, CSE1L, RAB3D, TOMM20, IPO5, TOMM22, DMBT1, KPNA6, CHP1, RAB2A, ATG9A, VPS33B, TIMM8A1, CHMP4B, PPID, KPNB1, COPB2, COPA, ENY2, PKDCC, TSG101, TMED10, GPR89, ARL3, COPB1, FAM21, PSEN1, TIMM50, RAP1A, TPR, RAB6A, AP1M2, DNAJC19, RAB4A, ANKRD27, RAB4B, TIMM44, DNAJC15, NASP, HOOK2, NACA, CHMP2B, CHMP2A, RAB5A, CNIH4, COPE, MCFD2, ARRB1, USE1, SEC61A1, AP1G2, AP1G1, NUP62, TIMM17B, ERC1, TNPO2, EIF5A, AMN, JAGN1, PDCD6IP, ARFGAP3, RABEP1, PEX5, MYH9, SFT2D2, CHMP6, CHMP5, SEC23A, RAB1B, GOSR2, RRBP1, SELENBP1, RAB25, RAB24, MVB12A, ARFGEF1, TIMM8B, RAB10, GOLPH3, RAB14, RAB15, VPS41, RANGRF, RAB17, RAN",3331,592,18082,1.81557969,4.07E-15,8.15E-16,7.99E-16 GOTERM_BP_DIRECT,GO:0006397~mRNA processing,127,3.414896478,9.81E-19,"EIF4A3, HNRNPU, PNN, ALKBH5, PPP4R2, SNRPD2, SNRPD1, KHSRP, MAGOH, PAPOLA, ARL6IP4, CIR1, SNRPD3, PRKACA, SRRM2, MBNL1, MBNL2, SSU72, THOC3, WBP11, THOC7, JMJD6, SRRM1, ERN2, RBMXL1, DDX39B, XRN2, SRSF2, SRSF3, SNRPE, GEMIN7, SRSF5, SNRPF, AURKAIP1, SNRNP200, SRSF6, SRSF7, SNRPA, SF1, SNRPB, SRSF9, SLBP, KHDRBS1, DDX5, RBM8A, YTHDC1, DDX1, PRPF8, PCBP1, HSPA8, CPSF7, PRPF38B, CPSF6, CPSF1, NONO, ALYREF, CPSF3, LSM1, CWC15, LSM4, LSM2, HNRNPL, HNRNPM, HNRNPK, SNW1, LSM6, SON, HNRNPF, RNPS1, HNRNPC, RBM25, DDX46, CELF1, AKAP8L, CELF3, ADAR, YBX1, PRPF19, PQBP1, PTBP1, SYNCRIP, C1QBP, DHX15, BCAS2, RBM17, CNOT6L, NCBP2, PTBP3, SFPQ, THRAP3, HNRNPH1, ESRP1, FRG1, LUC7L3, STRAP, SNRPA1, PABPC1, SKIV2L2, TSEN34, SF3B4, SF3B5, RNASEL, SF3B3, SRSF1, U2AF1, SCAF8, PUF60, PABPN1, U2AF2, TRA2B, TRA2A, SNRPB2, RBBP6, SRSF10, SF3B1, SF3A3, DDX39, RBM39, SF3A1, HNRNPA3, PPIL1, PTCD2, WTAP, PHF5A, HNRNPA2B1, ACIN1, TARDBP",3331,322,18082,2.141014859,6.55E-15,9.51E-16,9.33E-16 GOTERM_BP_DIRECT,GO:0008380~RNA splicing,104,2.796450659,9.97E-19,"EIF4A3, HNRNPU, PNN, PPP4R2, SNRPD2, SNRPD1, KHSRP, MAGOH, ARL6IP4, CIR1, SNRPD3, SRRM2, MBNL1, MBNL2, SCAF11, THOC3, WBP11, THOC7, JMJD6, SRRM1, RBMXL1, DDX39B, SRSF2, SRSF3, SNRPE, GEMIN7, SRSF5, SNRPF, SNRNP200, SRSF6, SRSF7, SNRPA, SF1, SNRPB, SRSF9, DDX5, RBM8A, YTHDC1, PRPF8, HSPA8, PRPF38B, NONO, ALYREF, LSM1, CWC15, LSM4, LSM2, HNRNPM, HNRNPK, SNW1, LSM6, SON, HNRNPF, RNPS1, HNRNPC, RBM25, DDX46, CELF1, CELF3, YBX1, PRPF19, PQBP1, PTBP1, SYNCRIP, C1QBP, DHX15, BCAS2, RBM17, NCBP2, PTBP3, SFPQ, THRAP3, HNRNPH1, ESRP1, FRG1, LUC7L3, STRAP, SNRPA1, PABPC1, SKIV2L2, SF3B4, SF3B5, SF3B3, SRSF1, U2AF1, SCAF8, PUF60, U2AF2, TRA2B, TRA2A, SNRPB2, SRSF10, SF3B1, SF3A3, DDX39, RBM39, SF3A1, HNRNPA3, PPIL1, WTAP, PHF5A, HNRNPA2B1, ACIN1, TARDBP",3331,241,18082,2.342546006,6.66E-15,9.51E-16,9.33E-16 GOTERM_BP_DIRECT,GO:0016192~vesicle-mediated transport,93,2.500672224,3.03E-17,"ARF3, ARF4, MCFD2, ARF1, KDELR1, GOLT1A, CLTC, GDI2, CLTB, CLTA, MIA3, FNBP1L, CLINT1, USE1, AP2A2, AP1G2, AP1G1, CHMP1A, TMED2, TRAPPC11, AP1S1, AP3S1, RAB2A, SEC13, JAGN1, STX8, VPS33B, STX7, AP1B1, AP3B1, ARFGAP3, COPZ1, VAMP8, TRAPPC6A, RABEP1, TRAPPC6B, STX5A, PREB, KDELR2, SFT2D2, ERGIC3, ERGIC1, ARF5, OPTN, VAMP3, ARF6, NAPA, RTN3, COPB2, COPA, SEC23A, TMED10, SAR1A, STX17, STX16, STXBP1, GOSR2, CUL3, COPB1, STXBP2, USO1, LMAN1, SCFD1, AP2S1, STX3, RAB6A, AP1M2, SEC31A, VTI1B, BCAP31, ARFGEF1, GSN, CACFD1, TRAPPC10, TRAPPC4, GBF1, YIPF5, AP3D1, RAB27A, TVP23B, SYT13, AP2B1, RAB11A, YIF1A, ARCN1, RAB10, MYO5B, VPS41, COPG1, COPE, CNIH4, MON1A, PICALM",3331,213,18082,2.370146426,2.03E-13,2.53E-14,2.48E-14 GOTERM_BP_DIRECT,GO:0006629~lipid metabolic process,155,4.16778704,3.19E-15,"LPGAT1, ACAA2, HDLBP, GDE1, H2-KE6, TM7SF2, LIPE, LIPH, HADH, FADS1, CPT1A, MECR, PCYT2, DGAT2, ECH1, ACSL6, ACSL5, ACSL3, PISD, SULT2B1, PLA2G16, ACLY, CLPS, SOAT1, SOAT2, FDX1, PLBD1, SLC27A2, SLC27A4, CDS1, ISYNA1, MTMR3, INSIG1, MTTP, PLD1, ADIPOR2, PLD3, CYB5R1, ATP5B, EBP, CYB5R3, NPC1L1, PSAP, PMVK, DECR2, APOB, FDFT1, FDPS, XBP1, CHKB, CHKA, SRD5A1, EPT1, DHCR24, CRLS1, ACADSB, PRDX6, PAFAH2, CYP51, SULT1B1, FASN, SERINC1, DEGS1, DHCR7, DEGS2, LRP10, PNLIPRP2, ACADVL, DAGLA, GAL3ST1, MOGAT2, TECR, PTEN, PRKAG1, PCSK9, PRKAG2, AACS, SMPD3, SMPD2, HINT2, SPTLC1, SPTLC2, CPT2, ACADL, HNF4A, ACP6, CYP4V3, SCD2, HMGCS2, SCD1, ACADM, ACADS, SREBF1, ELOVL1, CERS4, PLA2G12A, LYPLA1, GPX1, HMGCS1, APOA1, SREBF2, HADHB, HADHA, PLCB3, SULT1D1, NPC2, ACOX1, EHHADH, MVD, PPARA, PAFAH1B3, MGLL, PAFAH1B1, CERS2, AGPAT5, ASAH1, ECHS1, ASAH2, MVK, ATP5A1, GDPD1, HSD17B4, SGMS2, ACAA1A, HMGCR, AGPAT1, HSD17B11, ACNAT1, AGPAT2, AGPAT3, HMGCL, FAM213B, SC5D, SPTSSA, CEPT1, CDIPT, LDLR, PLA2G2F, PTGES2, PTGES3, MID1IP1, PLA2G2A, DDHD2, APOC3, FABP5, CES1D, APOC2, ETNK1, LPCAT3, NDUFAB1, CHPT1, 0610007P14RIK, CRAT, LPIN2, PNPLA2",3331,459,18082,1.833119785,2.15E-11,2.21E-12,2.17E-12 GOTERM_BP_DIRECT,GO:0008152~metabolic process,156,4.194675988,3.31E-15,"LPGAT1, ACAA2, EPRS, CNDP2, LIPE, SCP2, ACAD11, ECH1, ACSL6, ACSL5, MOGS, ACSL3, HDHD3, UPB1, ALDH3A2, ERN2, ACLY, MTHFD1, MTHFD2, PGP, SUCLG2, SUCLG1, SLC27A2, GNE, SLC27A4, TSTA3, PFKFB4, DNMT1, TPH1, CTBP2, CTBP1, IREB2, LYZ1, UAP1, GNS, ACAT2, ACAT1, GM3776, MAN2A1, ALDH3B1, UAP1L1, HLTF, ISOC1, DPH5, NADK, FDFT1, GSTM3, MGEA5, GSTM2, GSTM1, PDHA1, EDEM1, FUCA1, ACADSB, PRDX6, PAICS, GRHPR, CPS1, FASN, MYO5B, OGDH, ACO1, ALDH18A1, ACO2, PAM, GSTM7, GSTM6, GALK2, GALK1, GM10639, ACADVL, ALAS1, ACY1, HEXB, TREH, HEXA, AACS, HK2, ALAD, GYS1, ATIC, SPTLC2, ACADL, ALDH2, IDS, UGT2A3, PHGDH, HMGCS2, ME2, ACADM, ACADS, CAMK1D, TPI1, HMGCS1, GSTO1, GAA, PGAM1, CAD, HADHB, MAN1A, HADHA, UGDH, PKM, BDH1, ACOX1, EHHADH, ALDH1A1, UGT2B5, PDE5A, TKT, FBP1, GART, ALDH1A7, FBP2, ALDH9A1, AGPAT5, ECHS1, ACSS2, MVK, GSTP1, ACAA1A, AGPAT1, SAMHD1, NT5C3, AGPAT2, AGPAT3, PAPSS2, PAPSS1, PAK1, UGP2, ALDH1B1, OXCT1, PAK3, ACSS1, PAK2, UGT2B34, RRM1, CENPV, FAHD1, PKLR, GCH1, UGT2B36, UGT2B35, NAGA, GSTZ1, PFKL, SUCLA2, GSTA4, AADAC, GSTA3, GSTA2, ALDH16A1, CIAPIN1, PFKP, ENGASE, PNPLA2",3331,463,18082,1.829007303,2.22E-11,2.21E-12,2.17E-12 GOTERM_BP_DIRECT,GO:0006413~translational initiation,37,0.9948911,8.65E-15,"EIF4A2, EIF4A1, DDX3X, LARP1, EIF4H, EIF2S3X, DENR, EIF2B1, EIF4B, EIF2A, ABCF1, MCTS1, EIF5B, EIF2B2, EIF1AX, EIF2S2, EIF2S1, EIF1, EIF3M, EIF5, EIF6, EIF3K, EIF3L, EIF3I, EIF3G, EIF3H, EIF3E, EIF3F, EIF3C, EIF1A, EIF4E2, EIF3D, EIF1B, EIF3A, EIF4G2, EIF4G1, EIF3B",3331,54,18082,3.719459177,5.78E-11,5.25E-12,5.15E-12 GOTERM_BP_DIRECT,GO:0006749~glutathione metabolic process,33,0.887335305,6.43E-13,"GSTP1, GLO1, GSTT3, MGST1, GSTT1, HMGN5, GGT1, GSTM4, GSTK1, GSTM2, GSTM1, GPX1, GPX4, GSTO1, GPX3, IDH1, GSR, SOD2, SOD1, EEF1G, GSTZ1, GCLC, NAT8, GSTA4, GSTA3, GSTA2, ETHE1, CTH, GSTA1, G6PDX, HAGH, GCLM, GSTM7",3331,49,18082,3.655861144,4.30E-09,3.58E-10,3.51E-10 GOTERM_BP_DIRECT,GO:0006457~protein folding,59,1.58644797,2.34E-12,"TXN1, FKBP11, HSP90AB1, ERO1L, TXN2, TUBA1B, TUBB5, NUDCD2, QSOX1, CCT3, PDIA3, CCT2, HSP90AA1, NUDC, AHSA1, UBE4B, PDIA6, PDIA5, CDC37, CANX, TCP1, FKBP8, PPIF, PFDN1, PPIG, FKBP4, PPIB, PFDN5, PPIA, PPID, FKBP2, HSPA4L, HSP90B1, HSPD1, DNAJB6, GRPEL1, GRPEL2, CCT8, CCT7, CCT5, TXNDC5, NKTR, CCT4, HSPA9, CD74, TRAP1, HSPA8, PPIL1, ST13, TXNL1, HSPE1, DNAJA1, FKBP1A, CCT6A, ERP44, DNAJA3, DNAJA2, P4HB, CALR",3331,128,18082,2.50215307,1.56E-08,1.20E-09,1.18E-09 GOTERM_BP_DIRECT,GO:0042493~response to drug,115,3.092229094,1.11E-11,"PEBP1, COMT, SRP14, SLC8A1, AQP1, TXN2, CCND1, CDH1, DPYSL2, EP300, CAR9, HADH, JUNB, B2M, SPINK4, ABCG8, ABCG5, CPT1A, CYBA, CYP2D26, POR, RPP21, TXNIP, DNMT1, RPN2, MAOB, MGST1, GATA6, GSTT1, AK4, GATA3, PHB, NEUROD1, NPC1L1, MYO6, ATG5, FZD1, CBX7, JUN, XBP1, JUND, DEFA6, UBE2B, SRD5A1, DEFA3, GNAO1, CDK9, DAB1, CPS1, CDK4, TRP53, GNAS, CDK1, CALR, TCF3, GCLM, PAM, CDKN1A, CDKN1B, ABCD3, MCM7, PTEN, HMGB2, AACS, ALAD, XPO1, CASP1, UQCRFS1, CD38, TSPO, DGCR2, TGIF1, SREBF1, HSP90AA1, ABCC2, MMP7, HMGCS1, ITGA3, DNMT3A, SORD, APOA1, FOS, YWHAZ, RHOA, HADHA, DAD1, DPYD, CAT, ALDH1A1, PLIN2, TOP1, SRC, EI24, ADCY1, ATP1A1, ADD3, THBS1, HSPD1, CST3, DEFA17, SRP72, MAT2A, OXCT1, PTK2B, BAK1, BCHE, TRPA1, BAD, STAT3, SRP68, SOD2, SOD1, CTNNB1, FOSB, OTC",3331,339,18082,1.841492585,7.43E-08,5.31E-09,5.21E-09 GOTERM_BP_DIRECT,GO:0043066~negative regulation of apoptotic process,169,4.544232321,2.59E-11,"ARL6IP1, ZFAND6, ARAF, CIB1, PARK7, PHB2, AQP1, IGF1R, CCND2, HMGN5, FNTA, RPS6KA1, AKT1, PIM3, PIM2, SOX9, BNIP3L, KDM2A, RPS6, MIF, ATAD3A, POR, NCL, CLDN7, FKBP8, PPIF, PHIP, ATF5, NAIP1, FAIM, GLO1, GATA6, PIK3R1, PSEN1, PHB, HIGD1A, PRKCZ, HIF1A, HSP90B1, PLAC8, BAG6, PRDX3, PRDX5, PDCD10, MICAL1, BAG1, ATG5, MCL1, PRNP, JUN, XBP1, PRELID1, UBE2B, HSPA5, HSPA4, PLK1, ASNS, DHCR24, PA2G4, PAFAH2, NFKB1, HIGD2A, GCLC, HNRNPK, NAT8, SON, QARS, TRP53, GNAQ, BCL3, ID1, ALB, PPT1, CDK1, HYOU1, PSMG2, ANP32B, BCL2L2, GSK3B, ARF4, CDKN1A, BTG2, CDKN1B, DDX3X, HSP90AB1, CITED2, CHD8, PTEN, FHL2, SLC40A1, ADAR, YBX1, YBX3, ALDH2, RB1CC1, NUP62, MYO18A, CASP2, CD38, YWHAH, EIF5A, GPX1, CAMK1D, TSC22D1, DUSP1, SPHK2, NME2, TGFBR1, TNFRSF1A, DNAJC3, DDB1, HAX1, TMBIM4, DAD1, CAT, TAX1BP1, BIRC5, TMBIM6, GAS6, CD44, LTF, PDXK, TMF1, SRC, HDAC1, GSTP1, AMIGO2, TAF9, HMGCR, THBS1, EGFR, HSPD1, FAM129B, CKMT1, CLN3, MIEN1, EPCAM, ERBB2, UCP2, CXCR2, CTNNA1, PTK2B, PAK2, MUC4, ATOH1, AAMDC, MAP4K4, CD74, NQO1, NPM1, BNIP3, STAT3, HIP1R, GCG, SOD2, GFER, VEGFA, SOD1, FABP1, DNAJA1, GOLPH3, KRT18, APC, RPS3A1, CTH, PDCD4, SPRY2, CIAPIN1, LAMTOR5",3331,566,18082,1.620847314,1.73E-07,1.15E-08,1.13E-08 GOTERM_BP_DIRECT,"GO:0002479~antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent",23,0.618445819,8.11E-11,"H2-T23, H2-K1, H2-T3, PSMB10, PSMA7, PSMB8, TAPBP, PSMB6, PSMA5, PSMB7, PSMA6, PSMB4, PSMA3, PSMB5, PSMA4, PSMA1, PSMB2, PSMB3, PSMA2, PSMB1, CALR, B2M, H2-D1",3331,30,18082,4.161773241,5.41E-07,3.38E-08,3.32E-08 GOTERM_BP_DIRECT,"GO:0000398~mRNA splicing, via spliceosome",50,1.344447432,5.24E-10,"DDX46, DQX1, PRPF19, UBL5, SNRNP70, DHX15, TXNL4A, BCAS2, NCBP2, BUD31, SRRM1, DDX39B, NHP2L1, SNRPG, SNRPE, SNRPA1, SNRPF, SNRPC, SNRNP200, SNRPA, SF1, SNRPB, SF3B5, SF3B2, SF3B3, YTHDC1, U2AF1, PRPF8, DHX32, ZMAT2, U2AF2, TRA2B, TRA2A, SNRPB2, SRSF10, SF3B1, ZRSR1, SF3A3, DDX39, SF3A1, NONO, CWC15, LSM2, HNRNPM, LSM7, SNW1, LSM6, PHF5A, HNRNPA2B1, HNRNPC",3331,112,18082,2.423392804,3.50E-06,2.06E-07,2.02E-07 GOTERM_BP_DIRECT,GO:0050821~protein stabilization,54,1.452003227,1.20E-09,"ZFP207, USP33, PTEN, PARK7, IFI30, PHB2, LAMP1, SUMO1, LAMP2, CHP1, EP300, PIM2, GOLGA7, SOX4, CCT3, CCT2, USP7, APOA1, ATP1B3, ATP1B1, GTPBP4, HCFC1, PEX6, CDC37, TCP1, PFN1, PPIB, GAPDH, STXBP1, TAF9, PIK3R1, PHB, USP19, HSPD1, TBRG1, BAG6, PDCD10, DVL1, CCT8, CCT7, TSPAN1, CCT5, CCT4, NPM1, UBE2B, HPS4, HIP1R, CCT6A, TRP53, GNAQ, PIN1, CALR, TCF3, RAB3GAP1",3331,128,18082,2.290106199,7.99E-06,4.44E-07,4.36E-07 GOTERM_BP_DIRECT,GO:0006446~regulation of translational initiation,23,0.618445819,1.51E-09,"EIF4A2, EIF5B, EIF4A1, PPP1R15B, EIF2B2, NCBP2, EIF1, EIF3M, EIF5, EIF3K, EIF3L, EIF3I, EIF3G, EIF4EBP1, EIF3E, EIF3F, EIF2B1, EIF3C, EIF3D, EIF3A, EIF4G2, EIF4G1, EIF3B",3331,33,18082,3.783430219,1.01E-05,5.30E-07,5.19E-07 GOTERM_BP_DIRECT,GO:0034976~response to endoplasmic reticulum stress,38,1.021780048,1.83E-09,"PPP1R15A, PPP1R15B, UBA5, SEL1L, ATP2A2, PIK3R1, THBS1, USP19, HERPUD1, ERO1L, SCAMP5, PPP2CB, OS9, UBQLN1, TXNDC5, PDIA3, XBP1, SDF2L1, HSPA5, UBE4B, EEF2, EIF2S1, PDIA6, PDIA5, ERP44, ERN2, UFM1, TMEM259, TMEM33, DNAJC10, UFC1, TMBIM6, ANKS4B, HYOU1, P4HB, TARDBP, ATF4, NFE2L2",3331,76,18082,2.71419994,1.22E-05,6.12E-07,6.00E-07 GOTERM_BP_DIRECT,GO:0008202~steroid metabolic process,40,1.075557946,3.80E-09,"MVK, INSIG1, MTTP, HDLBP, PCSK9, CYP3A13, HMGCR, TM7SF2, CYB5R1, LIPE, EBP, CYB5R3, NPC1L1, CYP2B10, PMVK, SC5D, HMGCS2, APOB, SLC37A4, LDLR, FDFT1, SREBF1, FDPS, G6PC, HMGCS1, SRD5A1, APOA1, DHCR24, SREBF2, CYP51, DHRS4, SULT2B1, SULT1B1, SOAT1, SOAT2, NPC2, FDX1, MVD, 0610007P14RIK, DHCR7",3331,84,18082,2.584952324,2.53E-05,1.21E-06,1.18E-06 GOTERM_BP_DIRECT,GO:0006695~cholesterol biosynthetic process,22,0.59155687,5.51E-09,"IDI1, FDPS, MVK, HMGCS1, INSIG1, APOA1, APOA4, DHCR24, HMGCR, CYP51, TM7SF2, EBP, CYB5R3, CES1D, NPC1L1, G6PDX, PMVK, MVD, HMGCS2, DHCR7, CFTR, FDFT1",3331,32,18082,3.732024917,3.68E-05,1.67E-06,1.64E-06 GOTERM_BP_DIRECT,GO:0001889~liver development,43,1.156224792,6.03E-09,"CEBPA, ONECUT2, PRKCSH, CITED2, CEBPG, GATA6, PCSK9, AK4, AACS, ACAT1, HMGCL, CCND1, MAN2A1, RB1CC1, SLCO2B1, ASL, HES1, ACADM, JARID2, SEC63, MKL2, JUN, XBP1, PTCD2, HMGCS1, SRD5A1, TAF10, CAD, COBL, ASNS, LSR, SOD2, GFER, UPB1, IGF2R, QDPR, PKM, DDX39B, SP1, HNRNPD, KRAS, ARF6, OTC",3331,95,18082,2.457065209,4.03E-05,1.73E-06,1.70E-06 GOTERM_BP_DIRECT,GO:0046034~ATP metabolic process,25,0.672223716,6.22E-09,"ATP6V1A, VCP, ATP5A1, OLA1, AK2, ATP5K, ATP5C1, ATP5J, AK3, AK4, ATP5H, ATP5O, ATP5G1, ATP5L, ATP5B, GUK1, ATP5D, HSPA8, BAD, ENTPD5, AMPD2, ATP1B1, ATP5J2, ATP6V1B2, NDUFS1",3331,40,18082,3.392749925,4.15E-05,1.73E-06,1.70E-06 GOTERM_BP_DIRECT,GO:0001731~formation of translation preinitiation complex,19,0.510890024,7.25E-09,"MCTS1, EIF3M, EIF5, EIF3K, EIF3L, EIF3I, EIF3G, EIF4H, EIF3H, EIF3E, EIF2S3X, DENR, RPS2, EIF3F, EIF3C, EIF3D, EIF3A, EIF4B, EIF3B",3331,25,18082,4.125583909,4.84E-05,1.94E-06,1.90E-06 GOTERM_BP_DIRECT,GO:0006915~apoptotic process,160,4.302231783,1.18E-08,"APP, MTCH1, ARL6IP1, ZFAND6, PDCD6, PDCD5, UBE2D3, CIB1, GHITM, ERO1L, CCAR1, PYCARD, TIAL1, SLK, FAM162A, RASSF6, EP300, AKT1, PIM3, PIM2, PGLYRP1, PHLDA1, SH3GLB1, BNIP3L, UNC5A, APLP1, PRKCD, SHISA5, PRKCA, TICAM1, NISCH, NAIP2, ERN2, NAIP5, DDIT4, FKBP8, PPIF, JTB, VDAC1, SQSTM1, NAIP1, PPID, FAIM, RTN3, BEX2, ITPR1, CDCA7, PSEN1, GABARAP, ZFP36L1, BAG6, PDCD10, RAD21, BAG1, S100A14, ATG5, MCL1, FIS1, TIA1, XBP1, PRELID1, SIVA1, RASSF7, RMDN3, NFKB1, GADD45G, VIL1, AIMP1, DAP, STK24, TRP53, CDK1, CYCS, CLPTM1L, FGFR3, OGT, BCL2L2, DIDO1, RBM25, DDX3X, FAF1, PTEN, PCSK9, ECE1, KRT20, LITAF, POLB, CASP7, HINT1, HINT2, AIFM1, CASP6, RFK, C1QBP, CASP1, CASP2, BOK, EIF5A, PDCD6IP, GPX1, DYNLL1, TGFBR1, TNFRSF1A, TOX3, PLSCR1, RABEP1, TRAF4, SLTM, TMBIM4, TMEM214, DAD1, IRF1, TAX1BP1, BIRC5, TMBIM6, ALDOC, GAPDH, PPP1R15A, ASAH2, MTFP1, ROCK1, TM2D1, EI24, PRUNE2, PURB, CST3, PAK1, BCLAF1, MIEN1, MUC2, PUF60, MKNK2, RPS3, MAPK1, POLR2G, APOPT1, BAK1, PAK2, MAPK3, BCAP31, EGLN3, GSN, 1600014C10RIK, BAD, TAF10, BNIP3, HIP1R, CCK, MAPK14, TRIM39, STK17B, DNAJA3, PDCD4, ACIN1, BAX, PKN2, PDCD2, LTBR, CIAPIN1, YPEL3",3331,570,18082,1.52376137,7.89E-05,3.03E-06,2.98E-06 GOTERM_BP_DIRECT,GO:0051289~protein homotetramerization,36,0.968002151,1.30E-08,"CDA, SHMT2, SHMT1, SAMHD1, HSD17B10, GLS, GOLGA2, RXRA, ACADL, PPAT, PCBD1, ACADM, REG1, TK1, ACADS, VASP, TRPA1, GPX3, DCXR, ATPIF1, GFPT1, ACOT13, HPRT, SOD2, APOA1BP, PFKL, SYT11, CTH, IMPDH2, CAT, ALDH1A1, ALDOC, ALDOA, FBP1, DCTPP1, PFKP",3331,74,18082,2.640843185,8.68E-05,3.21E-06,3.15E-06 GOTERM_BP_DIRECT,GO:0045727~positive regulation of translation,30,0.806668459,2.93E-08,"DDX3X, EIF4A3, THBS1, ELAVL1, RBM3, RPS4X, PTBP1, SERP1, ERBB2, PTK2B, MAPK1, EP300, SOX4, ABCF1, MAPK3, NPM1, CIRBP, UPF3B, LARP4B, EEF2, RHOA, TARBP2, HNRNPL, EIF6, DDX39B, CDK4, RPS3A1, BCL3, HNRNPD, EIF4G2",3331,57,18082,2.857052568,1.96E-04,6.99E-06,6.85E-06 GOTERM_BP_DIRECT,GO:0006099~tricarboxylic acid cycle,20,0.537778973,3.11E-08,"PDHA1, MDH1, MDH2, IDH3G, IDH1, IDH2, SDHC, SDHD, SDHA, SDHB, FH1, CS, SUCLA2, OGDH, IDH3B, SUCLG2, SUCLG1, ACO1, ACO2, IDH3A",3331,29,18082,3.743724055,2.08E-04,7.17E-06,7.03E-06 GOTERM_BP_DIRECT,GO:0016126~sterol biosynthetic process,19,0.510890024,4.83E-08,"FDPS, MVK, HMGCS1, INSIG1, DHCR24, HMGCR, CYP51, TM7SF2, CYB5R1, EBP, CYB5R3, PMVK, SC5D, MVD, HMGCS2, DHCR7, 0610007P14RIK, LBR, FDFT1",3331,27,18082,3.819985101,3.23E-04,1.08E-05,1.05E-05 GOTERM_BP_DIRECT,GO:0006979~response to oxidative stress,52,1.398225329,5.16E-08,"APP, BTG1, SRXN1, NDUFA12, PEBP1, PARK7, ALAD, AIFM1, AKT1, GPX2, GPX1, GPX4, GPX3, PRKCD, ATRN, NDUFS8, ALDH1A1, G6PDX, CAT, PPIF, TXNIP, NDUFS2, PPP1R15B, PON2, NDUFB4, PSEN1, EGFR, CST3, PRDX3, PRDX2, TRPM2, PRDX5, PSMB5, PRDX1, RPS3, PRNP, NQO1, NDUFA6, 1600014C10RIK, IDH1, TXNRD1, DHCR24, SOD2, ATOX1, NFKB1, SOD1, MSRA, GCLC, TRP53, SELK, GCLM, MSRB1",3331,133,18082,2.122381908,3.44E-04,1.11E-05,1.09E-05 GOTERM_BP_DIRECT,GO:0045454~cell redox homeostasis,32,0.860446357,6.84E-08,"TXN1, TXNDC9, GLRX, ERO1L, TXN2, PRDX3, PRDX2, PRDX5, PRDX4, AIFM1, PRDX1, QSOX1, TXNDC5, PDIA3, GPX1, GLRX3, PTGES2, GLRX5, TXNRD1, TXNL1, GSR, PDIA6, PRDX6, PDIA5, ERP44, GCLC, TMX2, DNAJC10, P4HB, DLD, VIMP, NFE2L2",3331,65,18082,2.672443018,4.57E-04,1.40E-05,1.37E-05 GOTERM_BP_DIRECT,GO:0006888~ER to Golgi vesicle-mediated transport,36,0.968002151,6.92E-08,"COPB2, VCP, SEC23A, COPA, STX17, COPB1, RAB1B, GOSR2, CUL3, USO1, TEX261, MIA3, IER3IP1, GOLGA2, LMAN1, LMAN2, VTI1B, BCAP31, SEC13, TRAPPC4, DDHD2, NRBP1, YIF1A, TRAPPC6A, VAPA, TRAPPC6B, RANGRF, STX5A, PREB, HYOU1, SEC24D, ERGIC3, SEC24C, ERGIC1, COPE, CNIH4",3331,78,18082,2.505415329,4.62E-04,1.40E-05,1.37E-05 GOTERM_BP_DIRECT,GO:0006417~regulation of translation,48,1.290669535,1.08E-07,"PPP1R15A, DDX6, PPP1R15B, APP, CDC123, DDX3X, RBM8A, RPLP1, IREB2, EPRS, ELAVL1, ZFP36L1, RBM3, RGS2, MKNK2, MAGOH, RPS3, EIF4EBP1, AKT1, RPL38, IGF2BP2, PAIP2, EIF2A, PTCD3, CNOT6L, NCBP2, APLP1, NGDN, RPL13A, PA2G4, LARP4B, PUM1, EIF2S1, MIF4GD, TARBP2, PUM2, PPP1CA, TNRC6C, DNAJC3, CNOT1, SARNP, ACO1, EIF4E2, LSM14A, TNRC6A, EIF4G2, EIF4G1, TNRC6B",3331,121,18082,2.153414828,7.19E-04,2.12E-05,2.07E-05 GOTERM_BP_DIRECT,GO:0015992~proton transport,29,0.779779511,2.12E-07,"ATP6V1A, ATP5A1, ATP5K, ATP5C1, ATP5J, ATP5G3, ATP5H, ATP5G2, ATP5O, ATP5G1, ATP5L, ATP5B, ATP5E, ATP5D, ATP6V1H, ATP6V1E1, ATP6V1D, ATP6V1C1, ATP6V1F, SLC36A1, ATP6V0B, ATP6V1G1, ATP6AP1, SLC11A2, ATP5F1, ATP5J2, ATP6V1B2, ATP6V0D1, ATP6V0E",3331,58,18082,2.71419994,0.001415618,4.05E-05,3.97E-05 GOTERM_BP_DIRECT,GO:0006886~intracellular protein transport,76,2.043560097,2.23E-07,"PDCD6, CSE1L, SRPR, CLTC, CLTB, CLTA, TOMM20, AP2A2, IPO5, TOMM22, HID1, XPO1, AP1G2, AP1G1, XPO6, TMED2, TIMM17B, AP1S1, VPS35, AP3S1, SEC61B, TNPO2, WLS, YWHAH, RAB2A, STX8, STX7, TBC1D8, AP1B1, CASK, AP3B1, COPZ1, SYTL2, CTTN, SCG5, STX5A, KPNB1, VIMP, NAPA, COPB2, COPA, SEC23A, TMED10, SAR1A, STX17, STX16, COPB1, USO1, KLC1, SNX1, SNX2, TBC1D13, AP2S1, STX3, RAB6A, SNX5, AP1M2, TBC1D16, VTI1B, SNX6, BCAP31, CD74, AP3D1, TIMM44, AP2B1, EHD1, RAB10, MLPH, SNX17, SGSM3, VPS41, COPG1, SEC24D, SEC24C, RAMP1, RAN",3331,232,18082,1.778268926,0.001490195,4.14E-05,4.06E-05 GOTERM_BP_DIRECT,GO:0016569~covalent chromatin modification,84,2.258671686,2.86E-07,"FOXA1, KDM5A, SETD3, SMARCB1, KDM1A, PHF20, CHD8, EHMT2, CHD7, SETD7, DPY30, EHMT1, ASH2L, CHD4, YEATS4, CTCF, NR3C1, MYSM1, RCBTB1, BABAM1, HMGN5, TRIM28, RUVBL2, EPC1, HMG20B, WHSC1, JARID2, HMGN3, KDM6B, BRD3, BRD2, PRMT5, PBRM1, SMARCC1, KDM2A, SMARCC2, H2AFY, EED, ATRX, DNMT3A, ASH1L, SIRT7, ARID1A, JMJD6, MSL1, HCFC1, MORF4L1, DNAJC2, NCOR1, MORF4L2, WAC, ZMYND11, ENY2, KDM3A, SMARCD2, DNMT1, HDAC1, UHRF1, BAZ2A, BAG6, MBTD1, RBBP4, NSD1, UBN1, HLTF, SMYD2, EP400, RBBP7, BRD8, SMYD3, RNF20, SMARCE1, CBX7, CBX6, CBX3, 0610010K14RIK, SETD1B, USP22, SMARCA5, CTCFL, ANP32E, OGT, FOXA3, FOXA2",3331,266,18082,1.714231541,0.001909666,5.17E-05,5.07E-05 GOTERM_BP_DIRECT,GO:1901998~toxin transport,21,0.564667921,3.55E-07,"CCT3, COPB2, CCT2, HSPA5, BNIP3, TRIP4, ARID1A, DNM1, COPZ1, PTPRG, RAB43, DNAJA1, CCT6A, SCFD1, MEP1B, TCP1, CASP1, CCT8, CCT7, CCT5, CCT4",3331,35,18082,3.257039928,0.002367659,6.24E-05,6.12E-05 GOTERM_BP_DIRECT,GO:0008637~apoptotic mitochondrial changes,18,0.484001076,3.95E-07,"MAP3K1, SOD2, HK2, HSPD1, CD24A, PPP2CB, GCLC, PNP, AIFM1, PPIF, AKT1, JTB, BAX, NDUFS1, PIM2, GCLM, SLC25A4, MCL1",3331,27,18082,3.618933253,0.002633459,6.76E-05,6.63E-05 GOTERM_BP_DIRECT,GO:0051603~proteolysis involved in cellular protein catabolic process,27,0.726001613,2.24E-06,"CTSZ, PSMA7, PSMB10, PSMB6, PSMB7, SCPEP1, PSMB4, PSMB5, PSMB2, PSMB3, CTSL, PSMB1, LONP1, CTSF, CTSB, CTSA, HSPA5, PSMB8, PSMA5, DNAJC3, PSMA6, PSMA3, PSMA4, PSMA1, PSMA2, CLPP, LGMN",3331,57,18082,2.571347312,0.014845604,3.74E-04,3.67E-04 GOTERM_BP_DIRECT,GO:0008203~cholesterol metabolic process,36,0.968002151,3.13E-06,"APP, CEBPA, MVK, INSIG1, MTTP, HDLBP, PCSK9, HMGCR, CLN6, TM7SF2, LIPE, EBP, CYB5R3, NPC1L1, PMVK, HMGCS2, APOB, LDLR, FDFT1, SREBF1, FDPS, HMGCS1, APLP2, APOA1, APOC3, DHCR24, APOA4, SREBF2, CYP51, SOAT1, SOAT2, NPC2, FDX1, CAT, MVD, DHCR7",3331,89,18082,2.195757255,0.02071161,5.10E-04,5.01E-04 GOTERM_BP_DIRECT,"GO:0006351~transcription, DNA-templated",421,11.32024738,4.46E-06,"ATF2, EHF, GABPB2, BACH1, PHB2, CREB3L3, CREB3L4, MYC, ZXDB, CREB3L1, ZXDC, MYB, GPBP1, BBX, JUNB, DDX17, HES6, PIH1D1, SOX13, DNTTIP2, BHLHA15, SND1, EID1, ZFP292, RFX6, EWSR1, SARNP, TXNIP, TBPL1, ATF5, ATF6, VPS25, ATF3, CGGBP1, SF1, PRR13, ATF4, CTBP2, CTBP1, FLII, GATA6, CDCA7, BAZ2A, GATA3, HIF1A, PRDM16, ZBTB7B, ZBTB7A, NKX2-2, BTF3, MCTS1, HEXIM1, JUN, JUND, SETD1B, NFATC3, IRF2BP1, TRIP4, IRF2BP2, PA2G4, PBX1, NR2F6, HNRNPK, HNRNPD, BTG2, SETD3, GMEB2, TCF25, PHF20, SETD7, BHLHE41, ASH2L, CTCF, TFCP2L1, MED16, LITAF, PQBP1, MED10, NELFB, JARID2, TRP53INP2, NELFE, BRD3, BRD2, CNOT6L, PAX6, SIRT7, ASH1L, DYNLL1, BAZ1B, MED28, AES, MED25, NCOR1, PPARA, ZFP148, ELOF1, TMF1, NR1I3, SRRT, NR1I2, ASCL2, BCLAF1, NSD1, RPS3, STAT6, BRD8, RUNX1T1, SPDEF, MBD3, PCGF6, STAT3, MBD2, ELP2, ELP3, HIPK1, LRPPRC, GTF2H5, GATAD2A, PHF5A, MYBBP1A, NFIA, NFIB, NFIC, PKN2, CTNND1, RORC, UBP1, YEATS4, RORB, BZW1, YY1, HMGN5, DACH1, RUVBL2, CIR1, MAF1, GTF2I, TLE2, FOXP4, GTF2F2, MYT1, FOXP1, MORF4L1, ILF3, MORF4L2, ADNP, SRSF5, KHDRBS1, DNMT1, ENY2, GTF2E2, NEUROD1, NACC1, SMYD2, SAFB2, ESRRA, CHTOP, HOPX, NFKB1, NFKB2, CNOT4, CDK9, MLXIPL, CDK8, SON, CNOT1, SP1, NACA, BCL3, NFE2L2, ZFP524, DIDO1, RNF10, ONECUT2, AKAP8L, FHL2, ARRB1, LBH, ZNRD1, SIN3B, UBTF, HMG20B, RFC1, ATRX, DNMT3A, EDF1, DNAJC2, POLR1C, POLR1D, BIRC5, ZFP410, LCORL, NFAT5, CEBPA, ZFP787, SMARCD2, GTF2A2, HDAC1, UHRF1, CEBPG, CXXC1, RBBP4, PUF60, POLR2B, POLR2C, WBP5, POLR2E, POLR2F, POLR2G, PCBD1, POLR2H, RBBP7, POLR2J, POLR2K, POLR2L, POLR2M, CNBP, CCDC59, KLF4, HNRNPAB, KLF3, CTCFL, PNRC2, KLF6, KLF5, ESF1, CEBPZ, INSM1, SMARCB1, KEAP1, RCBTB1, UBE2L3, CCAR1, PNN, TRIM28, EPC1, SOX9, TRIM27, CCNL2, CCNL1, SOX4, SMARCC1, SMARCC2, PTOV1, JMJD6, SUB1, XRN2, TFAM, PREB, ZFPM1, CASZ1, ANP32A, TSHZ1, MYCBP2, CTR9, ZBTB4, MBTD1, SEC14L2, HLTF, DHX36, ZFP740, ZFP512, EGR1, XBP1, SMARCA2, MED13L, ZZZ3, SNW1, FUBP1, ID1, PPP1R1B, ID3, CITED2, PPP1R10, HNF4G, WASL, LIMD1, HINT1, SCML4, HNF4A, ZMYM5, C1QBP, CHMP1A, MLX, SREBF1, PRMT5, TSC22D4, PBRM1, PARP1, TSC22D1, NCOA5, COMMD1, COMMD6, CBFA2T3, COMMD7, SREBF2, TOX3, SLTM, WAC, ZFP703, PRIM1, TCEAL8, PURB, RXRA, SERTAD1, CUX1, HSF2, TCEB2, GPBP1L1, TCEB1, CDX2, CDX1, CTNNB1, TCEA1, HDGF, TARDBP, FOXA3, FOXA2, FOXA1, TXN1, KDM1A, NR3C1, TTF1, ETS1, ETS2, CHCHD2, CHCHD3, CCND1, KHSRP, EP300, KDM2A, ARID5B, POU3F2, ERN2, LMX1A, NUPR1, DDX5, DDX1, DEAF1, CAMTA1, BPTF, HSPA8, CBX7, ZFHX3, CBX6, CBX3, VDR, PHF12, NONO, SMAD5, FEV, TRP53, BHLHE40, TCF3, RERE, KDM5A, DDX3X, THRA, CHD8, CHD7, HMGB2, DPY30, HMGB3, ADAR, CHD4, YBX1, YBX3, MYSM1, AFF4, SFR1, RB1CC1, NUP62, WHSC1, MKL2, TGIF1, KLF10, RBM14, KLF13, EED, DDX54, ARID1A, SAFB, ETV6, ELF1, SFPQ, ELF3, EEF1D, THRAP3, IRF1, IRF2, IRF7, IRF6, ZMYND11, KDM3A, ATF6B, DDX21, RNF4, TAF1D, SAP30L, ERBB2, MAPK1, HES1, ATOH1, MAPK3, RBM39, TCF7L2, CHURC1, TAF10, USP22, SSRP1, MAPK14, USF2, MAPK13, 2700060E02RIK, TEF, SLIRP, SSBP2, LPIN2, SSBP3, TAF1",3331,1885,18082,1.212390636,0.029332127,7.09E-04,6.95E-04 GOTERM_BP_DIRECT,"GO:0048025~negative regulation of mRNA splicing, via spliceosome",16,0.430223178,4.62E-06,"NPM1, PTBP3, HNRNPL, PTBP1, RBMXL1, HNRNPK, U2AF2, C1QBP, TRA2B, HNRNPA2B1, ACIN1, RNPS1, SRSF6, SRSF7, SRSF10, SRSF9",3331,25,18082,3.474175923,0.030374643,7.17E-04,7.04E-04 GOTERM_BP_DIRECT,GO:1904874~positive regulation of telomerase RNA localization to Cajal body,12,0.322667384,5.33E-06,"CCT6A, CCT3, CCT2, DKC1, RUVBL2, TCP1, NHP2, CCT8, CCT7, CCT5, NOP10, CCT4",3331,15,18082,4.342719904,0.034973208,8.09E-04,7.94E-04 GOTERM_BP_DIRECT,GO:0006364~rRNA processing,45,1.210002689,7.64E-06,"RPL5, POP5, RNASEL, DDX27, RRP1, RPL11, CHD7, EIF4A3, DDX21, RBFA, RPL7, EXOSC7, RPS15, RRP7A, FBL, EMG1, EXOSC5, RPS17, RPS16, YBEY, RPS19, RPL14, GAR1, RPS7, IMP3, PIH1D1, RPS6, RPL35A, IMP4, UTP11L, PA2G4, WBP11, GTF2H5, ISG20, EBNA1BP2, NSA2, RPS28, LSM6, DKC1, MRTO4, FRG1, NHP2, NOP10, SKIV2L2, RPS24",3331,126,18082,1.938714243,0.049708179,0.001111059,0.001089757 GOTERM_BP_DIRECT,GO:0015986~ATP synthesis coupled proton transport,15,0.40333423,7.66E-06,"ATP6V1A, ATP5A1, ATP5K, ATP5C1, ATP5J, ATP5G3, ATP5H, ATP5G2, ATP5F1, ATP5O, ATP5G1, ATP5L, ATP5B, ATP5E, ATP5D",3331,23,18082,3.540260791,0.049824821,0.001111059,0.001089757 GOTERM_BP_DIRECT,GO:0009749~response to glucose,32,0.860446357,8.73E-06,"PFKFB2, CDKN1B, PTPRN, PTEN, THBS1, SLC8A1, KHK, TXN2, NEUROD1, UCN3, CASP6, CTSL, HNF4A, PTK2B, EP300, EIF2B1, SLC37A4, GLUL, NKX2-2, NDUFA9, EGR1, TCF7L2, SREBF1, EIF2B2, PKLR, BAD, RHOA, MLXIPL, PFKL, TXNIP, VIMP, SIDT2",3331,78,18082,2.227035848,0.056627907,0.001240303,0.001216522 GOTERM_BP_DIRECT,"GO:0048026~positive regulation of mRNA splicing, via spliceosome",13,0.349556332,9.16E-06,"SF3B4, HSPA8, DAZAP1, CELF3, EIF4A3, PRPF19, RBMXL1, SNW1, THRAP3, SNRNP70, TRA2B, TRA2A, SLC39A5",3331,18,18082,3.920511024,0.059290167,0.001273339,0.001248925 GOTERM_BP_DIRECT,GO:0007623~circadian rhythm,40,1.075557946,1.00E-05,"GSK3B, DDC, DDX5, TPH1, HDAC1, DHX9, MTTP, BHLHE41, RORC, HNRNPR, ADCY1, EGFR, MAT2A, UBB, NAMPT, UBC, PRKG2, EP300, RPS27A, KLF10, SREBF1, JUN, CPT1A, JUND, NONO, CSNK1D, CLDN4, NCOR1, CDK4, THRAP3, TRP53, DPYD, BHLHE40, ID1, ID3, PPARA, ATF5, UBA52, LGR4, ATF4",3331,108,18082,2.010518474,0.064825132,0.001367784,0.001341559 GOTERM_BP_DIRECT,"GO:0045893~positive regulation of transcription, DNA-templated",148,3.979564399,1.09E-05,"EHF, RORC, RORB, FGF1, ETS1, ETS2, IGF1R, PSMD9, TRIM28, CDH1, ZXDB, MYC, GPBP1, RPS6KA1, ZXDC, MYB, EP300, PIM2, SOX9, SOX4, MAP2K3, DDX17, SMARCC1, MAP2K2, SMARCC2, FBXW11, FOXP1, ILF3, RFX6, TFAM, PHIP, ATF5, ATF4, ENY2, DDX5, MAGED1, GATA6, GATA3, PSEN1, PHB, MRPL12, HIF1A, NEUROD1, NUP85, DEAF1, PRDM16, DVL1, BPTF, ESRRA, FZD1, EGR1, JUN, ZFHX3, SMARCA5, NFATC3, TRIP4, SMARCA2, NFKB1, MLXIPL, SP1, TRP53, FEV, BCL3, TCF3, PICALM, NFE2L2, RNF187, KDM5A, RNF10, SETD3, CITED2, CHD8, SETD7, HMGB2, HNF4G, CTCF, MED16, CKS1B, LBH, SFR1, HNF4A, TMSB4X, NUP62, CD38, TRP53INP2, YWHAH, MKL2, SREBF1, PBRM1, RFC1, RHOG, PAX6, FOS, ARID1A, RGMB, SREBF2, TGFBR1, CCNA2, DNAJC2, TOX3, PPM1A, ELF1, ELF3, THRAP3, IRF1, WAC, IRF7, CKS2, IRF6, PPARA, CEBPA, KDM3A, SRC, HDAC1, NR1I2, CXXC1, RNF6, RNF4, RXRA, CAND1, SERTAD1, NSD1, MAPK1, GPBP1L1, HES1, PCBD1, RNF20, TCF7L2, NPM1, CHURC1, CDX2, PTGES2, CNBP, USP22, STAT3, KLF4, USF2, HNRNPAB, CTCFL, PHF5A, KLF5, NFIA, NFIB, CTNNB1, TCEA1, SSBP3, LGR4, FOXA2",3331,576,18082,1.394797191,0.070299809,0.001457854,0.001429903 GOTERM_BP_DIRECT,GO:0006338~chromatin remodeling,32,0.860446357,1.19E-05,"FOXA1, RERE, SMARCD2, SMARCB1, CEBPG, CHD7, BAZ2A, GATA3, NR3C1, TTF1, MYSM1, CHRAC1, RBBP4, MYC, RUVBL2, MYB, HMG20B, SOX9, RBBP7, BPTF, SMARCE1, SMARCC1, SMARCC2, PIH1D1, ATRX, SMARCA5, ARID1A, BAZ1B, SMARCA2, MORF4L1, MORF4L2, TOP1",3331,79,18082,2.198845521,0.076095041,0.001551875,0.00152212 GOTERM_BP_DIRECT,GO:0034314~Arp2/3 complex-mediated actin nucleation,12,0.322667384,1.42E-05,"ACTR3, ACTR2, ARPC2, ARPC3, ARPC1B, JMY, ARPC1A, ARPC5L, ARPC4, TRIM27, ARPC5, IQGAP2",3331,16,18082,4.07129991,0.09048927,0.001823996,0.001789025 GOTERM_BP_DIRECT,GO:0006694~steroid biosynthetic process,27,0.726001613,1.48E-05,"MVK, TECR, H2-KE6, HMGCR, HSD17B11, TM7SF2, CYB5R1, EBP, HINT2, CYB5R3, SCP2, PMVK, SC5D, TSPO, HMGCS2, FDFT1, FDPS, HSD3B7, HMGCS1, SRD5A1, DHCR24, PBX1, CYP51, FDX1, MVD, 0610007P14RIK, DHCR7",3331,62,18082,2.363980593,0.093827252,0.001858955,0.001823313 GOTERM_BP_DIRECT,GO:0007584~response to nutrient,30,0.806668459,1.70E-05,"AHCY, COX4I1, PTEN, HMGCR, ADIPOR2, AACS, SLC8A1, TXN2, ALAD, HMGCL, OXCT1, SLC37A4, BCHE, ABCG8, NQO1, ABCG5, SLC6A19, ADSL, PKLR, APOA1, ACSL3, SUOX, GCLC, POR, DAD1, DPYD, GCLM, CCL28, SLC27A4, PLEC",3331,73,18082,2.230849266,0.107407357,0.002104148,0.002063805 GOTERM_BP_DIRECT,GO:0008283~cell proliferation,67,1.801559559,1.90E-05,"GSK3B, DAZAP1, KDM1A, MCM7, CITED2, PAK1IP1, PARK7, MKI67, FGF1, UBE2L3, CKS1B, DACH1, MYC, RAC1, GLUL, CDK5RAP3, APPL2, BOK, GPX1, SPHK2, ENTPD5, MIF, AXIN2, GNL3, MORF4L1, PRKAR1A, DKC1, IRF2, DDIT4, CKS2, RPL29, CFB, PDXK, ENPEP, ASAH2, SRC, UHRF1, MVP, SRRT, FURIN, EGFR, ZFP36L1, GNAI2, RAP1B, PURB, LARP1, PRDX1, MAP7, BAK1, TSPAN1, CD74, TCF7L2, H3F3B, BAD, PTGES3, TXNRD1, H3F3A, STAT3, VEGFA, GOLPH3, NASP, GNB1, CDK1, CTNNB1, BAX, MAP3K11, PICALM",3331,220,18082,1.653194509,0.119016536,0.002303913,0.00225974 GOTERM_BP_DIRECT,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,235,6.318902931,2.03E-05,"APP, ATF2, EHF, GABPB2, SMARCB1, EIF4A3, BACH1, RPS6KA4, PSMD9, CREB3L3, CREB3L4, ZMIZ2, CREB3L1, MYC, RPS6KA1, NAMPT, MYB, EPC1, AKT1, SOX9, CCNL2, CCNL1, JUNB, SOX4, CDK5RAP3, DDX17, SMARCC1, BHLHA15, ZFP292, RFX6, TFAM, RBCK1, PFN1, ATF5, ZFPM1, ATF6, ATF3, ATF4, BEX2, CTBP2, CTR9, GATA6, GATA3, PIK3R1, HIF1A, PLAC8, PCBP1, MYO6, HLTF, DHX36, ZBTB7B, NKX2-2, EGR1, JUN, XBP1, JUND, NFATC3, SMARCA2, PBX1, HNRNPK, MC1R, SNW1, TOP2A, ARF4, SETD3, CITED2, PTPRN, HEXB, ASH2L, PPP3CA, NIPBL, HNF4A, MED10, NELFE, SREBF1, PARP1, NME2, PAX6, ASH1L, FOS, SREBF2, PLSCR1, MED25, PPARA, ZFP148, RNASEL, NR1I3, NR1I2, EGFR, RXRA, SERTAD1, EPCAM, HSF2, TCEB2, STAT6, BRD8, AAMDC, SPDEF, EGLN1, CDX1, STAT3, WWP2, VEGFA, NFIA, NFIB, NFIC, CTNNB1, TCEA1, FOSB, HDGF, FOXA3, FOXA2, FOXA1, KDM1A, CD81, NUCKS1, PARK7, FGF1, NR3C1, ETS1, ETS2, YY1, CHCHD2, RUVBL2, STK16, KPNA6, EP300, CIR1, ARID2, HMGN3, CASK, MYT1, POU3F2, GTF2F2, FOXP1, RBMXL1, LMX1A, NCL, MORF4L2, PHIP, DDX5, CBFB, NEUROD1, DEAF1, BAG1, CAMTA1, SMYD3, ESRRA, VDR, SMAD5, NFKB1, NFKB2, CDK9, MLXIPL, COPS5, RGCC, CCPG1, SP1, TRP53, BCL3, PIN1, TCF3, OGT, NFE2L1, NFE2L2, RNF10, GSK3B, GSK3A, DDX3X, THRA, ONECUT2, LDB1, CHD8, CHD7, AKAP8L, SLC40A1, HMGB2, ARRB1, YBX1, HMGB1, MYSM1, FLCN, PTBP1, MCF2L, SUMO2, MKL2, KDM6B, RBM14, KLF13, H2AFZ, ATRX, PPP2R5B, ABHD14B, SAFB, ETV6, TNFRSF1A, ELF1, HAX1, ELF3, THRAP3, IRF1, IRF2, IRF7, NFAT5, CEBPA, KDM3A, GTF2A2, HDAC1, WBP2, TAF9, CEBPG, RNF4, DLL1, MLLT6, HES1, ATOH1, MAPK3, IGBP1, TCF7L2, CHURC1, CNBP, KLF4, MAPK14, USF2, CTCFL, 2700060E02RIK, KLF6, KLF5, TEF, CEBPZ, SSBP2, SSBP3, LPIN2, SSBP4, TAF1",3331,995,18082,1.282084394,0.126518818,0.002415488,0.002369175 GOTERM_BP_DIRECT,GO:0006631~fatty acid metabolic process,51,1.371336381,2.82E-05,"ACADVL, ACAA2, TECR, PRKAG1, PRKAG2, H2-KE6, AACS, GHR, CPT2, ACADL, SCD2, SCD1, ACADM, HADH, ACADS, FADS1, ELOVL1, LYPLA1, CPT1A, MECR, ACOT11, ECH1, ACSL6, ACSL5, ACSL3, HADHB, HADHA, ACOX1, NDUFS6, EHHADH, PPARA, SLC27A2, MGLL, SLC27A4, ECHS1, HSD17B4, ACAA1A, ACNAT1, ADIPOR2, FAM213B, DECR2, PTGES2, PTGES3, ACADSB, FABP2, FASN, NDUFAB1, CRYL1, DEGS1, LPIN2, CRAT",3331,156,18082,1.774669192,0.171862969,0.003257244,0.003194793 GOTERM_BP_DIRECT,GO:0030433~ER-associated ubiquitin-dependent protein catabolic process,25,0.672223716,2.88E-05,"VCP, DERL1, AUP1, USP19, HSP90B1, ERLEC1, OS9, UBQLN1, SEC61B, UBXN4, EDEM1, AMFR, EDEM2, UBE4B, MARCH6, PSMC5, PSMC6, RNF103, PSMC3, PSMC4, JKAMP, PSMC1, DNAJC10, STT3B, VIMP",3331,57,18082,2.38087714,0.174688308,0.003257244,0.003194793 GOTERM_BP_DIRECT,GO:0043044~ATP-dependent chromatin remodeling,15,0.40333423,2.88E-05,"SMARCE1, MBD3, SMARCC1, SMARCD2, SMARCB1, SMARCC2, HDAC1, CHD8, MBD2, SMARCA5, CHD4, ARID1A, ACTB, RBBP4, HNRNPC",3331,25,18082,3.257039928,0.174841824,0.003257244,0.003194793 GOTERM_BP_DIRECT,GO:0006986~response to unfolded protein,23,0.618445819,3.92E-05,"XBP1, HSP90AA1, ATF6B, EDEM1, HSPA4L, DERL1, UPF3B, HSPE1, THBS1, HERPUD1, HSPD1, MANF, DNAJC3, ERN2, ERP44, CREB3L3, CREB3L4, JKAMP, CREB3L1, TMBIM6, STT3B, UBXN4, ATF6",3331,51,18082,2.448101907,0.230025163,0.004356539,0.00427301 GOTERM_BP_DIRECT,GO:0042542~response to hydrogen peroxide,25,0.672223716,4.05E-05,"PPP1R15B, SRC, PARK7, SLC8A1, HSPD1, PRDX3, PPP2CB, CASP6, PDCD10, PTK2B, BAK1, JUN, GPX1, TRPA1, LIG1, BAD, DUSP1, SOD2, EEF2, SOD1, GNAO1, STK24, CAT, TXNIP, SDC1",3331,58,18082,2.339827534,0.237160432,0.004437738,0.004352653 GOTERM_BP_DIRECT,GO:0021762~substantia nigra development,19,0.510890024,4.33E-05,"YWHAE, ZFP148, MAOB, HSPA5, S100A1, ATP5J, ATP5F1, ACTB, COX6B1, CDC42, YWHAQ, NDUFS3, MBP, CALM3, CKB, CALM1, FGFR3, CALM2, YWHAH",3331,38,18082,2.71419994,0.251091687,0.004663427,0.004574014 GOTERM_BP_DIRECT,GO:0030968~endoplasmic reticulum unfolded protein response,22,0.59155687,4.53E-05,"PPP1R15A, XBP1, ATF6B, EDEM1, AMFR, EDEM2, DERL1, BHLHA15, HERPUD1, ERO1L, DNAJC3, SERP1, CREB3L3, CCND1, CREB3L4, CREB3L1, UGGT1, ATF6, ATF3, VIMP, CDK5RAP3, NFE2L2",3331,48,18082,2.488016612,0.26093719,0.004799453,0.004707432 GOTERM_BP_DIRECT,GO:1904871~positive regulation of protein localization to Cajal body,8,0.215111589,4.80E-05,"CCT6A, CCT3, CCT2, TCP1, CCT8, CCT7, CCT5, CCT4",3331,8,18082,5.42839988,0.274090275,0.00500503,0.004909068 GOTERM_BP_DIRECT,GO:0006754~ATP biosynthetic process,14,0.376445281,4.90E-05,"PKLR, ATP5A1, ATP5K, CHCHD10, ATP5C1, GBAS, ATP5O, ATP5L, ATP5J2, ATP5B, PKM, ATP5E, ATP5D, ALDOA",3331,23,18082,3.304243405,0.279111479,0.005034812,0.004938278 GOTERM_BP_DIRECT,GO:0006094~gluconeogenesis,15,0.40333423,5.18E-05,"TPI1, G6PC, PGAM1, GPI1, RBP4, G6PC3, GPD2, GPD1, PGK1, GAPDH, FBP1, ATF3, FBP2, ATF4, PCK2",3331,26,18082,3.131769161,0.292375748,0.005176531,0.005077281 GOTERM_BP_DIRECT,"GO:0006890~retrograde vesicle-mediated transport, Golgi to ER",16,0.430223178,5.20E-05,"ARF3, ARF4, COPB2, NBAS, COPA, TMED10, COPB1, GBF1, ARCN1, SCFD1, RER1, LMAN2, RAB6A, COPE, ARF5, ATP9A",3331,29,18082,2.994979244,0.293079166,0.005176531,0.005077281 GOTERM_BP_DIRECT,GO:0008654~phospholipid biosynthetic process,25,0.672223716,5.65E-05,"AGPAT5, CDS1, ISYNA1, LPGAT1, HEXB, AGPAT1, PLD1, AGPAT2, AGPAT3, CEPT1, CDIPT, SH3GLB1, CHKB, PCYT2, CHKA, EPT1, ACSL6, ACSL5, CRLS1, PISD, PLA2G16, LPCAT3, ETNK1, SERINC1, CHPT1",3331,59,18082,2.300169441,0.314236782,0.005547238,0.00544088 GOTERM_BP_DIRECT,GO:0005975~carbohydrate metabolic process,62,1.667114816,5.87E-05,"GSK3B, GSK3A, B4GALT1, HEXB, HEXA, HK2, KHK, GPI1, PPP1CB, NANP, AKT1, PGM2, PDK3, PGLS, PDK2, DCXR, GAA, TALDO1, PGD, YDJC, UGDH, HKDC1, G6PDX, GPD1, PGP, IDNK, HAGH, CHST4, B4GALT6, SIS, FBP1, GAPDH, FBP2, CHST2, B4GALT5, GALT, GLO1, SLC3A2, PPP1R2, LDHA, MAN2A1, AMDHD2, PGK1, MLEC, MGAM, PDHA1, MDH1, PKLR, MDH2, FUCA1, GFPT1, NAGA, PPP1CA, AIMP1, CS, GALE, PFKL, GNPDA2, MGAT4A, MGAT4B, GALM, GALK1",3331,206,18082,1.633790255,0.324149033,0.005677843,0.005568981 GOTERM_BP_DIRECT,"GO:0000381~regulation of alternative mRNA splicing, via spliceosome",19,0.510890024,6.66E-05,"SF3A1, MBNL1, DDX5, RBM25, MBNL2, RBM8A, WTAP, CELF3, EIF4A3, HNRNPL, PTBP1, RBMXL1, THRAP3, TRA2B, MAGOH, SRSF2, MALAT1, RNPS1, SRSF6",3331,39,18082,2.64460507,0.359129449,0.006355899,0.006234037 GOTERM_BP_DIRECT,GO:0006357~regulation of transcription from RNA polymerase II promoter,105,2.823339607,6.80E-05,"FOXA1, ATF2, EHF, SMARCB1, KDM1A, EHMT2, UBP1, NUCKS1, ETS1, ETS2, ZFP36, HMGN5, RUVBL2, EPC1, SOX9, HMGN2, JUNB, HMGN3, HMGN1, HES6, SMARCC2, ARID5B, POU3F2, RFX6, SUB1, PHIP, NUPR1, PFN1, ATF5, ATF3, CGGBP1, ATF4, ENY2, DDX5, MAGED1, CUL3, TSHZ1, GLO1, GATA3, DEAF1, RAD21, HLTF, SAFB2, XBP1, JUND, NFKB1, NFKB2, MED13L, MLXIPL, HNRNPK, SP1, TRP53, FUBP1, FEV, JMY, GNAS, TCF3, PAM, GMEB2, THRA, LDB1, CITED2, FHL2, HMGB2, HNF4A, MED10, MLX, HIST1H1C, BRD3, BRD2, KLF13, ANXA4, PAX6, FOS, SAFB, RHOA, AES, NCOR1, SLTM, CKS2, LCORL, CEBPA, ATF6B, CEBPG, NEDD8, ASCL2, TCEAL8, RXRA, HSF2, WBP5, HES1, TCF7L2, CDX2, ELP3, MAPK14, SOD2, KLF4, USF2, KLF5, TEF, CTNNB1, TCEA1, FOSB, FOXA3, FOXA2",3331,397,18082,1.43572289,0.364977572,0.006395486,0.006272864 GOTERM_BP_DIRECT,GO:0050892~intestinal absorption,12,0.322667384,7.18E-05,"FABP1, FABP2, VDR, MOGAT2, KCNQ1, IREB2, GCNT3, ACO1, SLC5A1, F11R, ABCB1A, TJP2",3331,18,18082,3.618933253,0.380908271,0.006659508,0.006531825 GOTERM_BP_DIRECT,GO:0043154~negative regulation of cysteine-type endopeptidase activity involved in apoptotic process,27,0.726001613,7.32E-05,"DDX3X, ARL6IP1, SRC, ARRB1, THBS1, HERPUD1, AQP1, GPI1, DNAJB6, MICAL1, RPS6KA1, AKT1, EP300, FNIP1, IGBP1, GPX1, DHCR24, KLF4, VEGFA, FABP1, NAIP2, POR, BIRC5, GAS6, NAIP1, CD44, LAMTOR5",3331,67,18082,2.187564131,0.386433722,0.006691084,0.006562795 GOTERM_BP_DIRECT,GO:0043161~proteasome-mediated ubiquitin-dependent protein catabolic process,48,1.290669535,7.52E-05,"VCP, GSK3A, PSMD12, UBXN2A, FAF1, CUL3, UBE2D3, KEAP1, RNF6, ARRB1, TNFAIP1, RNF4, PCNP, PSMD8, PPP2CB, PSMD6, PSMB5, RMND5A, PSMD4, BTBD1, HECTD3, PSMB3, PSMD2, BTBD2, PCBP2, SPOP, PSMD1, RNF44, UBE2I, UBE2B, FBXW11, WWP2, UBE4B, PPP2R5C, RAD23B, RBX1, PSMA5, DDB1, RNF145, UBE2W, RNF126, PSMC5, CDC34, UBE2R2, RNF181, RBCK1, NFE2L2, RNF187",3331,149,18082,1.74874627,0.394779295,0.006785719,0.006655615 GOTERM_BP_DIRECT,GO:0000028~ribosomal small subunit assembly,13,0.349556332,8.35E-05,"RPS5, RPS27L, RPSA, MRPS7, RPS15, RRP7A, RPS25, RPS14, RPS17, RPS28, RPS19, RPS2, RPS10",3331,21,18082,3.360438021,0.427289674,0.00743136,0.007288877 GOTERM_BP_DIRECT,GO:0090004~positive regulation of establishment of protein localization to plasma membrane,16,0.430223178,8.63E-05,"ITGB1, PRKCI, ITGA3, ARHGEF16, RHOG, CIB1, VIL1, DLG1, RER1, KIF5B, AGR2, AKT1, RANGRF, EZR, ARF6, PLS1",3331,30,18082,2.895146603,0.437772299,0.007576625,0.007431357 GOTERM_BP_DIRECT,GO:0000122~negative regulation of transcription from RNA polymerase II promoter,175,4.705566012,1.02E-04,"FOXA1, TXN1, ATF2, KDM1A, EHMT2, EHMT1, BACH1, ETS2, YY1, RPS14, ZFP36, CHCHD3, DACH1, TRIM28, CCND1, MYC, MYB, EPC1, EP300, CIR1, TRIM27, SOX9, HMGN2, JUNB, HES6, SMARCC2, S100A1, ARID5B, FOXP4, HCFC1, FOXP1, EID1, SARNP, TXNIP, EZR, ZFPM1, SQSTM1, ATF3, PPID, CGGBP1, DNMT1, DDX5, CTBP2, CTBP1, CUL3, CTR9, GATA6, GATA3, PSEN1, PHB, ZBTB4, HIF1A, ZNHIT1, PRDM16, TPR, SMYD2, ZBTB7A, BPTF, WDTC1, ESRRA, HEXIM1, EGR1, CBX7, JUN, CBX6, ZFHX3, XBP1, JUND, UBE2I, VDR, PHF12, PLK1, IRF2BP1, IRF2BP2, HOPX, NFKB1, NR2F6, NFKB2, EFNA1, MLXIPL, DLG1, HNRNPK, SNW1, CNOT1, TRP53, ID1, BHLHE40, ID3, CALR, TCF3, PKIG, FGFR3, KDM5A, BTG2, CITED2, TCF25, CHD8, BHLHE41, FHL2, CHD4, YBX1, TFCP2L1, CTCF, YBX3, FLCN, NIPBL, XPO1, SIN3B, C1QBP, MLX, WHSC1, JARID2, HIST1H1C, NELFE, TGIF1, SREBF1, PRMT5, H2AFY, RFC1, EED, DNMT3A, SIRT7, ARID1A, CBFA2T3, SREBF2, ETV6, AES, DUSP22, SFPQ, MED25, NCOR1, STRAP, PPARA, ZMYND11, CEBPA, ZFP148, PCNA, HDAC1, UHRF1, CXXC5, ASCL2, PURB, PPP2CA, RXRA, CUX1, NSD1, SPOP, HES1, STAT6, RBBP7, FNIP1, SPDEF, MBD3, IGBP1, TCF7L2, PCGF6, CDX2, MBD2, WWP2, HIPK1, KLF4, HNRNPAB, VEGFA, GATAD2A, KLF5, NFIA, NFIB, NEDD4, NFIC, DNAJA3, HNRNPA2B1, CTNNB1, HDGF, INSM1, FRK",3331,729,18082,1.303113826,0.494445581,0.008857984,0.008688148 GOTERM_BP_DIRECT,"GO:0030970~retrograde protein transport, ER to cytosol",11,0.295778435,1.19E-04,"UFD1L, ERLEC1, VCP, OS9, SEL1L, DERL1, SEC61B, AUP1, VIMP, HERPUD1, HSP90B1",3331,16,18082,3.732024917,0.549182431,0.010213397,0.010017574 GOTERM_BP_DIRECT,GO:0043065~positive regulation of apoptotic process,90,2.420005378,1.30E-04,"ITGB1, TOP2A, MTCH1, GSK3B, MTCH2, B4GALT1, DDX3X, PDCD5, PTEN, PTPRF, CCAR1, PYCARD, SMPD2, SLK, AIFM1, SCP2, FAM162A, CASP6, C1QBP, RASSF6, CASP1, AKT1, CASP2, TSPO, PHLDA1, SOX4, TGM2, BOK, EIF5A, BNIP3L, USP7, CAMK1D, TSC22D1, DUSP1, RPS6, PRKCD, ANXA5, ANO6, UTP11L, PLSCR1, DDX19B, ALDH1A1, TXNIP, PDE5A, RBCK1, NUPR1, ATF6, PPID, ZFP622, SRC, MAGED1, GATA6, TEX261, PSEN1, HIF1A, UACA, HSPD1, NEUROD1, PPP2CA, BCLAF1, MUC2, RXRA, BAK1, SPDEF, EGLN1, TCF7L2, JUN, GADD45A, BAD, BNIP3, OSGIN1, HIP1R, CCK, IGF2R, GADD45G, DNAJA1, NET1, APC, CDK4, RPS29, TRP53, JMY, ACIN1, ID3, CTNNB1, BAX, PDCD2, DEGS1, RNPS1, MAP3K11",3331,335,18082,1.458376087,0.580624539,0.010999141,0.010788252 GOTERM_BP_DIRECT,GO:0042254~ribosome biogenesis,32,0.860446357,1.69E-04,"DDX3X, DDX27, RPL34, NIP7, RPLP0, MRPL36, MRPL10, RPL7A, EMG1, RPS18, C1QBP, GAR1, BRIX1, NOP56, NOP58, IMP3, IMP4, RPL34-PS1, GTPBP4, GNL3, EBNA1BP2, NSA2, RPS28, GNL3L, EIF6, DKC1, GM5766, MRTO4, FRG1, NHP2, TSR1, NOP10",3331,89,18082,1.951784226,0.677153838,0.014131045,0.013860109 GOTERM_BP_DIRECT,GO:1904851~positive regulation of establishment of protein localization to telomere,8,0.215111589,1.81E-04,"CCT6A, CCT2, DKC1, TCP1, CCT8, CCT7, CCT5, CCT4",3331,9,18082,4.825244338,0.701914536,0.014775828,0.014492529 GOTERM_BP_DIRECT,GO:0006511~ubiquitin-dependent protein catabolic process,48,1.290669535,1.81E-04,"UFD1L, USP15, VCP, USP38, USP10, USP33, CUL3, USP34, UBE2D3, FBXO25, UBR3, RNF6, PSMA7, USP19, HERPUD1, BAG6, PSMD4, PSMD3, TCEB1, SKP1A, TRP53INP2, RNF20, USP24, RANBP1, USP7, XBP1, UBE2B, UBE2C, USP9X, USP22, AMFR, ADRM1, UBE4B, UBE2G1, FBXO32, TRPC4AP, RBX1, PSMA5, PSMA6, PSMA3, PSMA4, PSMA1, UBE2S, PSMA2, UBE2N, SQSTM1, CUL4B, ANAPC2",3331,154,18082,1.691968794,0.702317514,0.014775828,0.014492529 GOTERM_BP_DIRECT,GO:0042744~hydrogen peroxide catabolic process,10,0.268889486,1.97E-04,"PRDX3, PRDX2, PRDX5, GPX1, GPX3, TXNRD1, PRDX1, CAT, APOA4, PRDX6",3331,14,18082,3.877428486,0.730890011,0.015813326,0.015510135 GOTERM_BP_DIRECT,GO:0030855~epithelial cell differentiation,26,0.699112665,2.08E-04,"CD63, EHF, ACADVL, GATA6, F11R, CNN3, CASP6, CTSB, FZD1, GSTK1, CPT1A, ANXA4, PIH1D1, RPSA, VEGFA, VIL1, SULT1B1, ELF3, CES1D, CDHR2, CDK1, ID3, TPP1, ALDOC, TAGLN2, VDAC1",3331,67,18082,2.106543237,0.750473513,0.016524356,0.016207532 GOTERM_BP_DIRECT,GO:0075522~IRES-dependent viral translational initiation,7,0.18822264,2.29E-04,"PTBP1, SSB, PCBP2, EIF3F, EIF3D, EIF3A, EIF3B",3331,7,18082,5.42839988,0.78351789,0.018000847,0.017655714 GOTERM_BP_DIRECT,GO:0009267~cellular response to starvation,24,0.645334767,2.32E-04,"KLF10, TCF7L2, SREBF1, SRD5A1, EHMT2, USP33, PCSK9, RNASE4, DNAJC15, PIK3C2A, 5330417C22RIK, SREBF2, CTSL, ALB, RRAGD, PIK3C3, FNIP1, GAS2L1, GAS6, GLUL, FADS1, TNRC6A, FOXA3, ATG5",3331,60,18082,2.171359952,0.787435561,0.018003843,0.017658653 GOTERM_BP_DIRECT,GO:0006465~signal peptide processing,11,0.295778435,2.42E-04,"IMMP1L, SPCS3, SPCS2, SPCS1, SPPL2A, FURIN, H13, SEC11A, SPPL3, PCSK5, SEC11C",3331,17,18082,3.51249404,0.801142208,0.018351931,0.018000067 GOTERM_BP_DIRECT,GO:0008299~isoprenoid biosynthetic process,11,0.295778435,2.42E-04,"FDPS, IDI1, COQ2, MVK, HMGCS1, PEX5, PMVK, MVD, HMGCS2, HMGCR, FDFT1",3331,17,18082,3.51249404,0.801142208,0.018351931,0.018000067 GOTERM_BP_DIRECT,GO:0071456~cellular response to hypoxia,35,0.941113202,2.74E-04,"ACAA2, SRC, HP1BP3, GATA6, PTEN, HIGD1A, NDRG1, HIF1A, SLC8A1, ERO1L, ZFP36L1, AQP1, NPEPPS, UCN3, IRAK1, FAM162A, LMNA, UBQLN1, EIF4EBP1, AKT1, BNIP3L, BAD, BNIP3, DNMT3A, SDHD, VEGFA, FABP1, CCNA2, RGCC, TRP53, GNB1, HYOU1, P4HB, SLC29A1, NFE2L2",3331,103,18082,1.844601901,0.839209533,0.020532619,0.020138944 GOTERM_BP_DIRECT,GO:0006096~glycolytic process,17,0.457112127,2.89E-04,"PFKFB2, TPI1, ALDOART1, PKLR, PGAM1, HK2, GPI1, PFKL, PKM, HKDC1, OGDH, PGK1, ALDOC, ALDOB, ALDOA, GAPDH, PFKP",3331,36,18082,2.563411054,0.855044338,0.021220308,0.020813448 GOTERM_BP_DIRECT,GO:0032543~mitochondrial translation,17,0.457112127,2.89E-04,"PTCD3, MRPS17, MRPS15, NDUFA7, MRPS16, MRPS24, MRPS34, MRPS12, MRPS18B, MRPS21, MRPS7, MRPL23, MRPL10, LARS2, MRPL2, MRPL51, CHCHD1",3331,36,18082,2.563411054,0.855044338,0.021220308,0.020813448 GOTERM_BP_DIRECT,GO:0014070~response to organic cyclic compound,29,0.779779511,3.13E-04,"BTG2, ABCD3, EIF4A3, NEDD8, MKI67, COMT, AACS, TXN2, ACAT1, FNTA, PSMB2, CTSL, NAMPT, CASP1, REG1, BAK1, SLC37A4, FADS1, VKORC1, CPT1A, TRPA1, CYP2J6, IDH1, EPHX1, ACSL3, NFKB1, DPYD, CDK1, PLIN2",3331,80,18082,1.967794956,0.876154384,0.022292334,0.021864919 GOTERM_BP_DIRECT,GO:0006734~NADH metabolic process,9,0.242000538,3.20E-04,"VCP, MDH1, MDH2, IDH3G, GPD2, GPD1, OGDH, IDH3B, IDH3A",3331,12,18082,4.07129991,0.881611864,0.022292334,0.021864919 GOTERM_BP_DIRECT,GO:1901673~regulation of mitotic spindle assembly,9,0.242000538,3.20E-04,"CHMP1B, PLK1, CHMP1A, TPR, CHMP2B, CHMP2A, CHMP4B, CEP97, CHMP5",3331,12,18082,4.07129991,0.881611864,0.022292334,0.021864919 GOTERM_BP_DIRECT,GO:0060213~positive regulation of nuclear-transcribed mRNA poly(A) tail shortening,9,0.242000538,3.20E-04,"TNRC6C, BTG2, ZFP36, CNOT1, POLR2G, PABPC1, TOB1, TNRC6A, TNRC6B",3331,12,18082,4.07129991,0.881611864,0.022292334,0.021864919 GOTERM_BP_DIRECT,GO:0032869~cellular response to insulin stimulus,31,0.833557408,3.28E-04,"GSK3A, SRC, GSTP1, PCSK9, PIK3R1, PRKCZ, IGF1R, ZFP36L1, GHR, PAK1, MYC, PPAT, UCP2, AKT1, YWHAG, RAB8A, WDTC1, PRKCI, XBP1, PKLR, PARP1, H2AFZ, SRD5A1, APRT, RAB10, GCLC, CEACAM1, HNRNPK, SP1, CDK4, SRSF5",3331,88,18082,1.91227723,0.888217717,0.022292334,0.021864919 GOTERM_BP_DIRECT,GO:0051028~mRNA transport,31,0.833557408,3.28E-04,"SLBP, ENY2, RBM8A, SRSF1, EIF4A3, ZFP36L1, ZFP36, XPO1, NUP85, KHSRP, NUP62, TPR, MAGOH, G3BP2, NUP88, IGF2BP2, EIF5A, HNRNPA3, SEC13, NUP210, NCBP2, ALYREF, THOC3, LRPPRC, THOC7, DDX39B, NUP50, ZC3H11A, HNRNPA2B1, SRSF3, SRSF7",3331,88,18082,1.91227723,0.888217717,0.022292334,0.021864919 GOTERM_BP_DIRECT,GO:0015991~ATP hydrolysis coupled proton transport,16,0.430223178,3.30E-04,"ATP6V1A, ATP6V0B, ATP6AP1, ATP5A1, ATP5G3, ATP1A1, ATP5G2, ATP5G1, ATP5B, ATP6V1B2, ATP6V1H, ATP6V0D1, ATP6V1E1, ATP6V1C1, ATP6V1F, ATP6V0E",3331,33,18082,2.631951457,0.889835866,0.022292334,0.021864919 GOTERM_BP_DIRECT,GO:0051726~regulation of cell cycle,37,0.9948911,3.31E-04,"FOXA1, ITGB1, CDKN1A, 2810417H13RIK, CCNI, CTBP1, ZFP703, SRC, PTEN, PPP2CA, CCND2, CCND1, BAK1, GAS2L1, CLIC1, JUNB, HSPA8, JUN, NPM1, JUND, GADD45A, STAT3, PUM1, GADD45G, SFPQ, COPS5, RGCC, SON, APC, CDK4, TRP53, ID3, BAX, SRSF5, PSMG2, ATF5, TARDBP",3331,112,18082,1.793310675,0.890003409,0.022292334,0.021864919 GOTERM_BP_DIRECT,GO:0043525~positive regulation of neuron apoptotic process,26,0.699112665,3.53E-04,"ATF2, GSK3B, GSK3A, PCSK9, NR3C1, PTPRF, CDC42, AIFM1, CASP6, BAG1, CASP2, PAK3, EGR1, NQO1, JUN, RHOA, TNFRSF1A, CDC34, TRP53, CTNNB1, PIN1, BAX, FGFR3, MAP3K11, ATF4, UBE2M",3331,69,18082,2.045484013,0.905054598,0.023540381,0.023089038 GOTERM_BP_DIRECT,GO:0042149~cellular response to glucose starvation,15,0.40333423,3.72E-04,"SH3GLB1, XBP1, MTMR3, HSPA5, SLC2A1, ASNS, BHLHA15, HIGD1A, MYBBP1A, TRP53, PICK1, PIK3C3, UPP1, ATF4, NFE2L2",3331,30,18082,2.71419994,0.916631478,0.024594279,0.024122729 GOTERM_BP_DIRECT,GO:0030036~actin cytoskeleton organization,44,1.18311374,4.02E-04,"PRR5, ROCK1, ROCK2, FLII, BRK1, PDGFA, FHL3, WASL, CORO1B, CORO1C, SDCBP, CLN3, ABR, SLC9A3R1, PAK1, DNAJB6, CSRP1, CAPZB, TMSB4X, PACSIN2, ABL2, FLNB, RAC1, PAK3, TMSB10, MKL2, VASP, ACTR2, RHOG, SHROOM3, CORO2A, SSH2, RHOA, MTSS1, NISCH, SPECC1L, CDC42EP2, PFDN1, RHOU, KRAS, PFN1, RAN, BCAR1, PAFAH1B1",3331,142,18082,1.682039399,0.931683245,0.026304519,0.025800178 GOTERM_BP_DIRECT,GO:0071353~cellular response to interleukin-4,14,0.376445281,4.11E-04,"XBP1, RPL3, HSP90AB1, HSPA5, RPLP0, KEAP1, GATA3, ALAD, TUBA1B, CDK4, IMPDH2, FASN, RPS2, MCM2",3331,27,18082,2.814725864,0.935889334,0.026665819,0.026154551 GOTERM_BP_DIRECT,GO:0016236~macroautophagy,13,0.349556332,4.44E-04,"ATG3, EI24, PIK3C2A, D17WSU92E, CLN3, NBR1, UBQLN1, ULK1, PIK3C3, SQSTM1, OPTN, TRP53INP2, ATG5",3331,24,18082,2.940383268,0.94826366,0.028470558,0.027924688 GOTERM_BP_DIRECT,GO:0071260~cellular response to mechanical stimulus,28,0.752890562,4.86E-04,"MTPN, GSK3B, ATP1A1, EGFR, AQP1, ARHGDIA, CASP1, DAG1, AKT1, CASP2, SOX9, RAC1, BAK1, GGT1, SLC38A2, MAPK3, MAP3K1, MMP7, GADD45A, BAD, BNIP3, CYBA, NFKB1, TNFRSF1A, GCLC, IRF1, CTNNB1, LTBR",3331,78,18082,1.948656367,0.960927856,0.030871984,0.03028007 GOTERM_BP_DIRECT,GO:0002181~cytoplasmic translation,16,0.430223178,4.91E-04,"RPL31, RPLP1, RPLP0, RPL22, RPL35A, RPL8, RPL9, RPL6, RPL7, RPL36, EIF4H, RPLP2, RPL22L1, RPL15, RPL29, EIF4B",3331,34,18082,2.55454112,0.962368854,0.030935072,0.030341949 GOTERM_BP_DIRECT,GO:0009636~response to toxic substance,30,0.806668459,5.03E-04,"GUCY2C, DDC, CDKN1A, MAOB, PON2, GSTP1, PEBP1, CST3, SCFD1, AIFM1, CDH1, DHX15, MAPK1, MBP, SLC18A2, MAPK3, GPX1, CHKA, EPHX1, DNMT3A, ASNS, FOS, CPS1, CES1D, CDK4, CDK1, SDC1, BAX, NUPR1, SRSF9",3331,86,18082,1.893627865,0.965187855,0.031373315,0.030771789 GOTERM_BP_DIRECT,GO:0010269~response to selenium ion,8,0.215111589,5.08E-04,"ALAD, GPX1, MAOB, SELM, RPLP0, GSTT1, SOD2, APOB",3331,10,18082,4.342719904,0.966293569,0.031381537,0.030779854 GOTERM_BP_DIRECT,GO:0016310~phosphorylation,146,3.925786502,5.24E-04,"PANK3, ARAF, TESK1, MYLK, IGF1R, RPS6KA4, SLK, STK16, RPS6KA1, PDK3, AKT1, PIM3, PIM2, PIP4K2C, PRKACA, SEPHS2, PRKACB, EPHB4, PDK2, EPHB3, MAP2K3, PRKCI, MAP2K2, PRKCD, CASK, PRKCA, CSNK1D, DGKZ, ERN2, MAPKAPK2, CMPK1, IDNK, ULK1, PI4K2A, GNE, PFKFB4, PKDCC, AK2, AK3, AK4, PRKCZ, IRAK1, GRK4, STK38, PMVK, PGK1, ABL2, PIP5K1B, IP6K1, MARK2, NADK, CDK18, CHKB, CHKA, PLK1, CLK2, CDK9, CLK1, ICK, CDK8, STK24, CDK4, WNK1, CDK1, ALDH18A1, FGFR3, MAP3K11, GALK2, GALK1, DDR1, GSK3B, GSK3A, SMG1, MAST3, MAST2, ADK, PIK3C2A, LIMD1, HK2, KHK, GUK1, RFK, PBK, PRKG2, TK1, JAK1, CAMK1D, SPHK2, ITPK1, MINK1, NME2, HUNK, BAZ1B, TGFBR1, NME1, PKM, HKDC1, KIT, FAM20B, PIK3C3, CAMK2B, PRPS2, PDXK, DTYMK, MVK, ROCK1, SRC, ROCK2, SGMS2, EGFR, PAPSS2, PAPSS1, CKMT1, PAK1, ERBB2, MKNK2, PTK2B, MAPK1, CSK, CKB, PAK3, PAK2, MAPK4, MAP4K4, MAPK3, MAP3K1, PKLR, RIOK3, RYK, CSNK1A1, LIMK2, STAT3, MAPK14, HIPK1, CDK11B, MAPK13, BCKDK, SNRK, PFKL, TAOK3, ETNK1, STK17B, PKN2, PFKP, FRK, TAF1",3331,612,18082,1.295010429,0.969687495,0.032066786,0.031451964 GOTERM_BP_DIRECT,GO:0006605~protein targeting,17,0.457112127,6.07E-04,"YWHAE, YWHAB, RPL11, HPS4, RAB27A, SYNJ2BP, YWHAZ, TOMM20, ZDHHC3, MLPH, SYNGR2, YWHAQ, OS9, SEC61G, MYO6, PICK1, YWHAG",3331,38,18082,2.428494683,0.982631269,0.036835033,0.036128789 GOTERM_BP_DIRECT,GO:0048511~rhythmic process,40,1.075557946,6.38E-04,"TOP2A, KDM5A, GSK3B, DDX5, MAGED1, HDAC1, DHX9, ROCK2, BHLHE41, RORC, HNRNPU, RORB, ADCY1, PPP1CB, NAMPT, EP300, KLF10, PRMT5, CBX3, FBXW11, NONO, GFPT1, CSNK1D, PPP1CA, NFKB2, SFPQ, MYBBP1A, TEF, SP1, THRAP3, TRP53, BHLHE40, ID1, HNRNPD, ID3, TOP1, PPARA, OGT, LGR4, ATF4",3331,128,18082,1.696374962,0.985904414,0.038383184,0.037647258 GOTERM_BP_DIRECT,GO:0006898~receptor-mediated endocytosis,23,0.618445819,6.47E-04,"IFITM3, AMN, DBNL, TFRC, CLTC, HIP1R, APOA1, ARHGAP27, EGFR, DNM1, HSP90B1, DNM2, ATP5B, CLN3, FTL1, CTTN, SNX17, FTH1, PPT1, HYOU1, CALR, APOB, PICALM",3331,60,18082,2.080886621,0.98668776,0.038550666,0.037811528 GOTERM_BP_DIRECT,"GO:0006122~mitochondrial electron transport, ubiquinol to cytochrome c",9,0.242000538,6.96E-04,"UQCRB, UQCRQ, UQCRC1, CYCS, PMPCB, UQCR10, UQCRC2, CYC1, UQCRH",3331,13,18082,3.758122994,0.990451912,0.041148623,0.040359674 GOTERM_BP_DIRECT,GO:0006006~glucose metabolic process,25,0.672223716,7.12E-04,"INPPL1, CACNA1A, PIK3R1, HK2, SERP1, MYC, AKT1, PGM2, PDK3, PDK2, WDTC1, TCF7L2, CPT1A, PDHA1, TPI1, DCXR, MAPK14, NISCH, AIMP1, PKM, FABP5, G6PDX, GALM, PPARA, GAPDH",3331,68,18082,1.99573525,0.99137712,0.04168109,0.040881932 GOTERM_BP_DIRECT,GO:0001933~negative regulation of protein phosphorylation,29,0.779779511,7.67E-04,"PPP1R15B, PTEN, PEBP1, FBLN1, CIB1, ARRB1, PSEN1, PARK7, CORO1C, PPP2CA, MICAL1, DVL1, BAG1, PBK, CHP1, XDH, CDK5RAP3, PRNP, HSPA4, PAX6, PRKCA, FKBP1A, IBTK, CTDSP2, DNAJC10, MYADM, INSM1, TARDBP, OGT",3331,84,18082,1.874090435,0.99404024,0.043863198,0.043022202 GOTERM_BP_DIRECT,GO:0006997~nucleus organization,12,0.322667384,7.70E-04,"H3F3B, GOLM1, CHMP1B, H3F3A, CHMP1A, LMNA, CHMP2B, MAP7, CHMP2A, CHMP4B, CHMP6, CHMP5",3331,22,18082,2.960945389,0.994138857,0.043863198,0.043022202 GOTERM_BP_DIRECT,GO:0034379~very-low-density lipoprotein particle assembly,7,0.18822264,7.73E-04,"ARF1, DGAT1, SOAT1, CES1D, SOAT2, APOC3, ACSL3",3331,8,18082,4.749849895,0.994265856,0.043863198,0.043022202 GOTERM_BP_DIRECT,GO:0007034~vacuolar transport,10,0.268889486,7.86E-04,"CLN3, NDFIP2, CHMP1B, CHMP1A, CHMP2B, CHMP2A, CHMP4B, ATP6V0D1, CHMP6, CHMP5",3331,16,18082,3.392749925,0.994754253,0.043863198,0.043022202 GOTERM_BP_DIRECT,GO:0006914~autophagy,43,1.156224792,7.94E-04,"VCP, STX17, USP10, RAB1B, EI24, CISD2, PSEN1, PARK7, HMGB1, FNBP1L, GABARAP, FAM134B, MAP1LC3B, LAMP1, RB1CC1, RAB24, UBQLN1, TMEM208, TRP53INP2, ATG5, ATG3, GABARAPL2, GABARAPL1, XBP1, ACBD5, 1600014C10RIK, ATG9A, 5330417C22RIK, RAB33B, VMP1, VAMP8, TMEM59, DAP, VPS41, ATG2A, CHMP4B, TMBIM6, ULK1, PIK3C3, HAP1, SQSTM1, OPTN, TECPR1",3331,142,18082,1.643811231,0.995038932,0.043863198,0.043022202 GOTERM_BP_DIRECT,GO:0001523~retinoid metabolic process,11,0.295778435,8.02E-04,"ADH4, ADH1, CYP2J6, RBP2, APOC2, APOC3, APOA1, APOA4, LDLR, DHRS3, ADH5",3331,19,18082,3.142757825,0.99526823,0.043863198,0.043022202 GOTERM_BP_DIRECT,GO:0042176~regulation of protein catabolic process,11,0.295778435,8.02E-04,"PPP2CA, CDC42, SERPINB1A, XPO1, UBXN2A, PSMD2, FAF1, ODC1, PSMD3, PSMD1, FURIN",3331,19,18082,3.142757825,0.99526823,0.043863198,0.043022202 GOTERM_BP_DIRECT,GO:1902600~hydrogen ion transmembrane transport,11,0.295778435,8.02E-04,"COX8A, SLC46A1, ATP6V0B, COX7B, UQCRB, AA467197, ATP5G3, UQCR10, ATP5G2, ATP5G1, ATP6V0E",3331,19,18082,3.142757825,0.99526823,0.043863198,0.043022202 GOTERM_BP_DIRECT,GO:0006366~transcription from RNA polymerase II promoter,42,1.129335843,8.26E-04,"NFAT5, GTF2A2, EHF, THRA, LDB1, GATA6, DDX21, ARRB1, MED16, HIF1A, SCAF8, POLR2B, DEAF1, MYC, POLR2C, DVL1, POLR2E, POLR2F, POLR2G, POLR2H, JUNB, POLR2J, POLR2K, POLR2L, EGR1, JUN, XBP1, JUND, KLF13, STAT3, TRIP4, PAX6, FOS, KLF4, USF2, GTF2F2, MED13L, RBMXL1, ELF3, THRAP3, FOSB, LCORL",3331,138,18082,1.652121703,0.995981472,0.04456696,0.043712471 GOTERM_BP_DIRECT,GO:0045471~response to ethanol,37,0.9948911,8.28E-04,"PSMD14, MAOB, EHMT2, GSTP1, SETD7, PTEN, PEBP1, PHB, HMGCR, GATA3, AACS, ALAD, EEF1B2, POLB, CCND1, OXCT1, MYC, EIF4EBP1, PTK2B, SDF4, BAK1, NQO1, GSN, BAD, STAT3, GOT2, PRKCA, EEF2, RHOA, SOD1, RBP4, TRP53, CAT, ALDH1A1, G6PDX, CDK1, CDO1",3331,117,18082,1.716673466,0.996028421,0.04456696,0.043712471 GOTERM_BP_DIRECT,GO:0032922~circadian regulation of gene expression,23,0.618445819,8.38E-04,"KDM5A, PRMT5, ZFHX3, MAGED1, HDAC1, GFPT1, BHLHE41, RORC, HNRNPU, CSNK1D, PPP1CA, PPP1CB, PPP1CC, NCOR1, MYBBP1A, NAMPT, BHLHE40, PRKG2, TOP1, PPARA, OGT, LGR4, ATF4",3331,61,18082,2.046773725,0.996285335,0.04474498,0.043887078 GOTERM_BP_DIRECT,GO:0001649~osteoblast differentiation,36,0.968002151,8.50E-04,"CBFB, DHX9, CLTC, FHL2, HSD17B4, DDX21, HNRNPU, ADAR, RRBP1, PHB, RPS15, SYNCRIP, FBL, ATP5B, TMSB4X, CREB3L1, AKT1, RPS11, JUNB, TRP53INP2, TPM4, H3F3B, H3F3A, HSPE1, SND1, GTPBP4, RSL1D1, RBMXL1, MYBBP1A, FASN, CAT, ERH, HNRNPC, IARS, SNRNP200, LGR4",3331,113,18082,1.729401732,0.996584158,0.04505489,0.044191045 GOTERM_BP_DIRECT,GO:0071320~cellular response to cAMP,20,0.537778973,8.97E-04,"APP, KDM1A, SRD5A1, RPLP0, ITPR1, AKAP7, ITPR3, SLC8A1, ZFP36L1, AQP1, RAP1B, RAP1A, CPS1, KCNQ1, FDX1, AKAP9, GPD1, EZR, SLC26A3, CFTR",3331,50,18082,2.171359952,0.997492947,0.047043714,0.046141737 GOTERM_BP_DIRECT,GO:0007568~aging,50,1.344447432,9.02E-04,"GSK3A, PTEN, PEBP1, LITAF, POLB, CASP7, SCP2, LONP1, AKT1, CASP2, TSPO, SLC18A2, FADS1, EIF5A, SREBF1, MMP7, DNMT3A, CACYBP, FOS, CANX, CAT, ALDOC, DLD, RPN2, HMGCR, IRAK1, UCP2, CTNNA1, BAK1, SLC12A2, MBD3, NQO1, JUN, GSN, JUND, GSS, AMFR, MBD2, STAT3, ATP2B1, SOD2, EEF2, EIF2S1, SOD1, NFKB2, GNAO1, MSRA, GCLC, GCLM, NFE2L2",3331,173,18082,1.568901699,0.997580786,0.047043714,0.046141737 GOTERM_BP_DIRECT,GO:0046686~response to cadmium ion,14,0.376445281,9.65E-04,"CAMK2B, PRNP, DTYMK, CDKN1B, GSS, SORD, MT1, SOD2, ALAD, GPI1, GCLC, CAT, CDK1, B2M",3331,29,18082,2.620606839,0.998408702,0.049923235,0.048966049 GOTERM_BP_DIRECT,GO:0071364~cellular response to epidermal growth factor stimulus,16,0.430223178,0.001018027,"MCM7, GSTP1, CAD, IQGAP1, ZFP36L2, EGFR, ZFP36L1, VIL1, EEF1A1, ZFP36, MYC, NCL, ERBB2, ID1, AKT1, SOX9",3331,36,18082,2.412622169,0.998886016,0.052279623,0.051277258 GOTERM_BP_DIRECT,GO:0010044~response to aluminum ion,6,0.161333692,0.001073533,"ALAD, QDPR, GLUD1, MAOB, LONP1, XDH",3331,6,18082,5.42839988,0.999231261,0.05429477,0.053253767 GOTERM_BP_DIRECT,GO:0006102~isocitrate metabolic process,6,0.161333692,0.001073533,"IDH3G, IDH1, IDH2, IDH3B, ACO2, IDH3A",3331,6,18082,5.42839988,0.999231261,0.05429477,0.053253767 GOTERM_BP_DIRECT,GO:0000387~spliceosomal snRNP assembly,13,0.349556332,0.001100124,"PRMT5, LSM4, SNRPD2, SNRPD1, CLNS1A, SNRPG, STRAP, SNRPE, GEMIN7, SNRPD3, SNRPF, SNRPC, SNRPB",3331,26,18082,2.71419994,0.999356424,0.055221254,0.054162489 GOTERM_BP_DIRECT,GO:0006891~intra-Golgi vesicle-mediated transport,12,0.322667384,0.001230909,"GABARAPL2, COPB2, COPA, CUX1, TRAPPC10, COPB1, GOSR2, RAB6A, COPE, COPZ1, RAB33B, VTI1B",3331,23,18082,2.832208633,0.999731486,0.060870709,0.059703625 GOTERM_BP_DIRECT,GO:0010243~response to organonitrogen compound,12,0.322667384,0.001230909,"VKORC1, GNAO1, CDKN1A, HMGCS1, CCND1, PSMB2, MGST3, CDK1, MGST1, MGST2, CDO1, AACS",3331,23,18082,2.832208633,0.999731486,0.060870709,0.059703625 GOTERM_BP_DIRECT,GO:0006635~fatty acid beta-oxidation,18,0.484001076,0.00132798,"ACADVL, CPT1A, ABCD3, ECHS1, ACAA2, ECH1, HSD17B4, ACAA1A, ACAT2, ACAT1, HADHB, HADHA, ACOX1, EHHADH, PEX5, ACADM, HADH, SLC27A2",3331,44,18082,2.220709042,0.999859667,0.065188217,0.063938353 GOTERM_BP_DIRECT,GO:0019433~triglyceride catabolic process,11,0.295778435,0.00133979,"LIPE, CPS1, DDHD2, APOC3, APOA1, APOA4, APOB, PRKACA, PRKACB, MGLL, PNPLA2",3331,20,18082,2.985619934,0.999870319,0.06528786,0.064036085 GOTERM_BP_DIRECT,GO:0006337~nucleosome disassembly,9,0.242000538,0.001363019,"SMARCE1, SMARCD2, SMARCC1, SMARCB1, HIST3H2A, SMARCC2, CEBPG, ARID1A, ARID2",3331,14,18082,3.489685637,0.999888971,0.065767603,0.064506631 GOTERM_BP_DIRECT,GO:0042632~cholesterol homeostasis,23,0.618445819,0.001369337,"ABCG8, XBP1, ABCG5, G6PC, DGAT2, MTTP, APOC3, PCSK9, APOA1, APOA4, AMPD2, TMEM97, EHD1, CD24A, NCOR1, SOAT1, NPC1L1, SOAT2, NPC2, LAMTOR1, APOB, SLC37A4, LDLR",3331,63,18082,1.981796782,0.999893563,0.065767603,0.064506631 GOTERM_BP_DIRECT,GO:0006897~endocytosis,51,1.371336381,0.001462857,"APP, TFRC, USP33, INPPL1, CLTA, ARRB1, STON2, PIK3C2A, FNBP1L, CLINT1, AP2A2, GHR, DPYSL2, RAC1, SH3GL1, RALBP1, DBNL, APLP1, CSNK1D, SCAMP1, EPN1, DNM1, NME1, DNM2, RABEP1, CTTN, NCL, SNX3, CDC42, CLN3, SNX1, SNX2, MYO6, PACSIN2, AP2S1, ATP6V1H, LDLR, SNX5, ATP9A, SNX6, SORT1, HIP1R, ARHGAP27, AP2B1, SYNJ2BP, RAB11B, EHD1, RAB17, RAB5A, PICALM, LRP11",3331,181,18082,1.529549137,0.999943041,0.069757373,0.068419904 GOTERM_BP_DIRECT,GO:0051262~protein tetramerization,17,0.457112127,0.001613185,"CPSF7, ADSL, CPSF6, SHMT2, SHMT1, TXNRD1, HMGCR, FH1, DNM1, IGF1R, DHRS4, OXA1L, HMGCL, RPS19, TRP53, CAT, ASL",3331,41,18082,2.25079995,0.999979153,0.076380316,0.074915865 GOTERM_BP_DIRECT,GO:0030041~actin filament polymerization,12,0.322667384,0.001897161,"VIL1, GSN, CTTN, MICALL2, COBL, MYH9, ARPC4, ANG, RAC1, MTSS1, MSRB1, GAS7",3331,24,18082,2.71419994,0.999996879,0.088225919,0.086534349 GOTERM_BP_DIRECT,GO:0034614~cellular response to reactive oxygen species,12,0.322667384,0.001897161,"PRDX3, PRDX5, SRC, TRP53, TPM1, PXN, ROMO1, PTPRK, PARK7, FOS, PDK2, SLC8A1",3331,24,18082,2.71419994,0.999996879,0.088225919,0.086534349 GOTERM_BP_DIRECT,GO:0001666~response to hypoxia,53,1.425114278,0.001908408,"CDKN1B, CITED2, ECE1, LIMD1, ETS1, SLC8A1, TXN2, ALAD, ALKBH5, PLAU, LONP1, CASP1, CD38, EP300, CAR9, REG1, SOX4, ADSL, CYBA, ACTN4, ATP1B1, CBFA2T3, RHOA, CLDN3, CAT, DDIT4, ACOT2, ANG, ALDOA, PPARA, ITPR1, HIF1A, ASCL2, HSP90B1, HSPD1, DPP4, CST3, PDLIM1, PAK1, SCFD1, UCP2, PTK2B, EGLN1, EGR1, EGLN3, PKLR, BNIP3, NFATC3, SOD2, VEGFA, CD24A, HYOU1, PAM",3331,192,18082,1.49846455,0.999997106,0.088225919,0.086534349 GOTERM_BP_DIRECT,"GO:0030388~fructose 1,6-bisphosphate metabolic process",7,0.18822264,0.001955877,"PFKL, ALDOC, ALDOB, ALDOA, FBP1, PFKP, FBP2",3331,9,18082,4.222088795,0.999997893,0.088225919,0.086534349 GOTERM_BP_DIRECT,"GO:0048024~regulation of mRNA splicing, via spliceosome",7,0.18822264,0.001955877,"KHDRBS1, TIA1, SON, YTHDC1, SRSF3, SRSF10, JMJD6",3331,9,18082,4.222088795,0.999997893,0.088225919,0.086534349 GOTERM_BP_DIRECT,GO:0000103~sulfate assimilation,7,0.18822264,0.001955877,"TXN1, SULT2B1, SULT1D1, TXNL1, PAPSS2, PAPSS1, TXN2",3331,9,18082,4.222088795,0.999997893,0.088225919,0.086534349 GOTERM_BP_DIRECT,GO:0006000~fructose metabolic process,7,0.18822264,0.001955877,"PFKFB2, PFKFB4, ALDOB, ALDOA, FBP1, FBP2, KHK",3331,9,18082,4.222088795,0.999997893,0.088225919,0.086534349 GOTERM_BP_DIRECT,GO:0018279~protein N-linked glycosylation via asparagine,14,0.376445281,0.002034291,"VCP, ST6GALNAC2, RPN1, MAGT1, DDOST, KRTCAP2, FUT8, STT3A, ST3GAL4, ST3GAL6, MGAT2, STT3B, UGGT1, ST3GAL1",3331,31,18082,2.45153543,0.999998753,0.091147148,0.089399569 GOTERM_BP_DIRECT,"GO:0042147~retrograde transport, endosome to Golgi",22,0.59155687,0.002133246,"RAB9, STX16, GOSR2, CLTC, GBF1, FAM21, FAM109A, GCC2, RNF126, SNX1, SNX2, AP1S1, STX5A, VPS35, ERC1, TRIM27, RAB6A, SNX5, VTI1B, PLEKHJ1, VAMP3, SNX6",3331,61,18082,1.957783563,0.999999357,0.093924755,0.092123921 GOTERM_BP_DIRECT,GO:0032091~negative regulation of protein binding,22,0.59155687,0.002133246,"GSK3B, ROCK1, KDM1A, USP33, PARK7, AES, GOLGA2, PPP1R2, CKMT1, PLSCR1, GNL3L, HNRNPK, MYC, DVL1, ID1, PIN1, BAX, TMBIM6, ADNP, PIM2, PPARA, ZFPM1",3331,61,18082,1.957783563,0.999999357,0.093924755,0.092123921 GOTERM_BP_DIRECT,GO:0000302~response to reactive oxygen species,11,0.295778435,0.002138491,"ALDH3A2, GPX1, GSTP1, PTPRN, PRDX1, CAT, PRKCA, SOD2, PRDX6, ATOX1, SOD1",3331,21,18082,2.843447556,0.999999379,0.093924755,0.092123921 GOTERM_BP_DIRECT,GO:0034644~cellular response to UV,18,0.484001076,0.002335878,"PCNA, KDM1A, PTPRK, PIK3R1, EIF2S1, AQP1, YY1, ERCC4, TRP53, RUVBL2, POLD1, PBK, MYEOV2, EP300, BAX, BAK1, N4BP1, TAF1",3331,46,18082,2.124156475,0.999999834,0.100745161,0.098813558 GOTERM_BP_DIRECT,GO:0007595~lactation,18,0.484001076,0.002335878,"DDR1, VDR, CAD, RPLP0, USF2, PRLR, HIF1A, HK2, VEGFA, APRT, NME1, SOCS2, CCND1, PPAT, CDO1, SLC29A1, XDH, PAM",3331,46,18082,2.124156475,0.999999834,0.100745161,0.098813558 GOTERM_BP_DIRECT,GO:0010824~regulation of centrosome duplication,10,0.268889486,0.002342294,"NPM1, XPO1, PDCD6IP, CHMP1B, CHORDC1, CHMP1A, CHMP2B, CHMP2A, CHMP4B, CHMP5",3331,18,18082,3.015777711,0.999999841,0.100745161,0.098813558 GOTERM_BP_DIRECT,GO:0051017~actin filament bundle assembly,15,0.40333423,0.00236699,"DBNL, ACTN1, USH1C, ACTN4, ESPN, CORO1B, CDC42, LIMA1, BAIAP2L2, MYO1B, ABL2, LCP1, EZR, PLS1, GAS7",3331,35,18082,2.326457091,0.999999865,0.100745161,0.098813558 GOTERM_BP_DIRECT,GO:0006614~SRP-dependent cotranslational protein targeting to membrane,8,0.215111589,0.002369232,"SEC61A1, SRP72, SRPR, SSR3, SRP68, SRP14, SRP9, SEC63",3331,12,18082,3.618933253,0.999999867,0.100745161,0.098813558 GOTERM_BP_DIRECT,GO:0051881~regulation of mitochondrial membrane potential,13,0.349556332,0.002409992,"PRELID1, TUSC2, PARK7, SOD2, SOD1, PRDX3, UBB, UCP2, BAX, NDUFS1, BCO2, BAK1, CLIC1",3331,28,18082,2.520328516,0.999999899,0.10182981,0.099877411 GOTERM_BP_DIRECT,"GO:1900153~positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay",9,0.242000538,0.002450972,"TNRC6C, ZFP36, CNOT1, PABPC1, TOB1, ZFP36L2, TNRC6A, ZFP36L1, TNRC6B",3331,15,18082,3.257039928,0.999999923,0.102909991,0.100936882 GOTERM_BP_DIRECT,GO:0043406~positive regulation of MAP kinase activity,20,0.537778973,0.002566206,"MAGED1, SRC, PRKCD, PDGFA, MIF, IQGAP1, PSEN1, FGF1, EGFR, ADRA2A, VEGFA, CD24A, CEACAM1, IRAK1, PDCD10, ERBB2, KIT, KRAS, PDE5A, CSK",3331,54,18082,2.010518474,0.999999965,0.107074948,0.105021984 GOTERM_BP_DIRECT,GO:0031647~regulation of protein stability,24,0.645334767,0.002691509,"CTSA, SH3GLB1, SREBF1, HSPA8, XBP1, NPM1, USP7, CD81, PTEN, USP19, PYCARD, PSMD8, CDC42, GNL3L, RNF128, SUMO1, ASPH, RNF149, LAMP2, TOMM7, MAPK1, KRAS, VPS35, SOX4",3331,70,18082,1.861165673,0.999999985,0.111605665,0.109465832 GOTERM_BP_DIRECT,GO:0035774~positive regulation of insulin secretion involved in cellular response to glucose stimulus,14,0.376445281,0.002855292,"TRPA1, BAD, ARRB1, GCG, SRI, HIF1A, RFX6, OXCT1, MPC2, KIF5B, PHPT1, C2CD2L, CFTR, TRPM4",3331,32,18082,2.374924947,0.999999995,0.11766622,0.115410187 GOTERM_BP_DIRECT,GO:0016477~cell migration,52,1.398225329,0.002889728,"ITGB1, GSK3B, ARF4, GSK3A, USP33, PTEN, TNFAIP1, PTPRK, LIMD1, PTPRF, NUP62, MYO18A, RAC1, TNS3, EPHB3, JAK1, PRKCI, RHOA, SPECC1L, ANG, LCP1, CD47, CD44, PAFAH1B1, HBEGF, CD63, ENPEP, CD151, SRC, CUL3, THBS1, PRKCZ, CORO1B, EFNB2, CLN3, FUT8, ABL2, CSK, HES1, TSPAN1, USP24, ST14, JUP, ARPC5, VEGFA, EFNA1, CD24A, GOLPH3, APC, FAT1, SDC1, BCAR1",3331,191,18082,1.477888973,0.999999996,0.118354744,0.116085509 GOTERM_BP_DIRECT,GO:0007049~cell cycle,141,3.791341759,0.003091664,"SMARCB1, ZFP207, GMNN, BCCIP, CIB1, MKI67, SMC3, SMC4, RCBTB1, CCAR1, GOLGA2, PPP1CB, PPP1CC, RGS2, CCND2, CCND1, EP300, PIM3, STRA13, PIM2, LIG1, FBXW11, PRKCD, MTUS1, HCFC1, EID1, CDC34, PARD3, SPECC1L, TXNIP, JTB, ERH, ANAPC5, ANAPC1, ANAPC2, ARL8B, LLGL2, ANAPC13, KHDRBS1, BEX2, TSG101, CDCA3, ARL3, ARPP19, ANAPC11, CCNB2, CHTF8, RAD21, TPR, MCTS1, CDT1, UBE2I, UBE2C, GADD45A, RCC2, PLK1, RGCC, SON, NASP, CDK4, UBE2S, CCPG1, REEP4, REEP3, TRP53, CDK1, PIN1, PRR5, CDKN1A, CDKN1B, MCM7, CETN3, HEPACAM2, KIF11, WASL, CKS1B, SMPD3, BABAM1, SEPT9, NIPBL, RB1CC1, CHMP1B, CHMP1A, WDR6, HMG20B, APPL2, NUDC, PDCD6IP, DUSP1, NSUN2, H2AFX, RHOA, CCNA2, INCENP, MCM3, CKS2, BIRC5, PIK3C3, MCM5, MCM6, MAPRE1, PAFAH1B1, MCM2, ARF6, AVPI1, CDC123, RALA, SRC, UHRF1, DCTN3, GNAI3, GNAI2, PPM1G, PCNP, TBRG1, RBBP4, RPS3, MAPK1, BUB3, MAPK4, MAPK3, GADD45GIP1, CGREF1, CENPV, WTAP, USP9X, CSNK1A1, USP22, CDK11B, RAB11A, MAPK13, PPP1CA, SGSM3, CDK2AP1, PKN2, NCAPD2, INSM1, SPC24, RAN, TAF1, CUL4B",3331,614,18082,1.246586943,0.999999999,0.124221686,0.121839964 GOTERM_BP_DIRECT,GO:0006068~ethanol catabolic process,6,0.161333692,0.003184392,"ADH1, ALDH2, ALDH1B1, ALDH3B1, ALDH1A7, ADH5",3331,7,18082,4.652914183,0.999999999,0.124221686,0.121839964 GOTERM_BP_DIRECT,GO:0043279~response to alkaloid,6,0.161333692,0.003184392,"BCHE, TMED10, MYC, UQCRC1, DHX15, SRSF9",3331,7,18082,4.652914183,0.999999999,0.124221686,0.121839964 GOTERM_BP_DIRECT,GO:0051683~establishment of Golgi localization,6,0.161333692,0.003184392,"CDC42, ARHGAP21, SLC9A3R1, PDCD10, COPG1, YWHAZ",3331,7,18082,4.652914183,0.999999999,0.124221686,0.121839964 GOTERM_BP_DIRECT,GO:0032532~regulation of microvillus length,6,0.161333692,0.003184392,"VIL1, CDHR2, USH1C, CDHR5, EZR, PLS1",3331,7,18082,4.652914183,0.999999999,0.124221686,0.121839964 GOTERM_BP_DIRECT,GO:1903608~protein localization to cytoplasmic stress granule,6,0.161333692,0.003184392,"TIA1, DDX3X, SSB, DHX9, DDX1, YBX1",3331,7,18082,4.652914183,0.999999999,0.124221686,0.121839964 GOTERM_BP_DIRECT,GO:0006595~polyamine metabolic process,6,0.161333692,0.003184392,"ODC1, OAZ1, SAT1, OAZ2, AZIN1, SRM",3331,7,18082,4.652914183,0.999999999,0.124221686,0.121839964 GOTERM_BP_DIRECT,GO:0006110~regulation of glycolytic process,6,0.161333692,0.003184392,"MLXIPL, EIF6, PGAM1, PRKAG2, HIF1A, OGT",3331,7,18082,4.652914183,0.999999999,0.124221686,0.121839964 GOTERM_BP_DIRECT,GO:0007030~Golgi organization,26,0.699112665,0.003200439,"TMED10, STX17, UBXN2A, CLTC, USO1, RAB43, CDC42, ARHGAP21, LMAN1, LMAN2, MYO18A, TMED2, RAB2A, ARFGEF1, TMED9, ATP8B1, CSNK1A1, SURF4, GBF1, GOLPH3L, CSNK1D, BHLHA15, VMP1, GOLPH3, GORASP2, OPTN",3331,79,18082,1.786561986,0.999999999,0.124221686,0.121839964 GOTERM_BP_DIRECT,GO:0070059~intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress,15,0.40333423,0.003225421,"GSK3B, XBP1, ITPR1, ERO1L, BAG6, ERN2, AIFM1, TRP53, DNAJC10, SELK, BAX, TMBIM6, BAK1, UBE2K, ATF4",3331,36,18082,2.261833283,1,0.124467706,0.122081267 GOTERM_BP_DIRECT,GO:0035690~cellular response to drug,25,0.672223716,0.003256995,"DDC, HSP90AB1, TFRC, EHMT2, SERPINE1, EGFR, MYLK, RAP1B, PPP3CA, RAP1A, MYC, PPAT, SLC18A2, GSTM3, PRNP, RANBP1, GSTM1, CAD, QDPR, RNF149, KCNQ1, TRP53, GAS6, FBP1, NFE2L2",3331,75,18082,1.809466627,1,0.124963796,0.122567845 GOTERM_BP_DIRECT,GO:0045862~positive regulation of proteolysis,11,0.295778435,0.003279285,"MGEA5, HSPA8, ASPH, FBXW11, BAD, PLK1, EP300, BAK1, AURKAIP1, OGT, CLN6",3331,22,18082,2.71419994,1,0.125100025,0.122701463 GOTERM_BP_DIRECT,GO:0009409~response to cold,16,0.430223178,0.003521298,"ACADVL, HSP90AA1, THRA, TRPA1, ACOT11, ATP2B1, FOS, SOD2, HSPD1, RBM3, PLAC8, PCSK1N, TMEM135, ACADL, ACADM, LRP11",3331,40,18082,2.171359952,1,0.133569218,0.131008274 GOTERM_BP_DIRECT,GO:0042274~ribosomal small subunit biogenesis,10,0.268889486,0.003728942,"RPS15, NPM1, RPS17, RPS28, RPS16, RPS7, RPS19, RPS6, UTP11L, RPS24",3331,19,18082,2.857052568,1,0.139793692,0.137113405 GOTERM_BP_DIRECT,GO:0006783~heme biosynthetic process,10,0.268889486,0.003728942,"ALAD, SNX3, SLC25A39, ALAS1, UROD, UROS, SLC11A2, ATPIF1, CPOX, TMEM14C",3331,19,18082,2.857052568,1,0.139793692,0.137113405 GOTERM_BP_DIRECT,GO:0000045~autophagosome assembly,17,0.457112127,0.003748213,"ATG3, GABARAPL2, GABARAPL1, ATG9A, PSEN1, 5330417C22RIK, GABARAP, MAP1LC3B, RB1CC1, ATG2A, UBQLN1, ULK1, PIK3C3, EMC6, CTSD, TRP53INP2, ATG5",3331,44,18082,2.097336317,1,0.139793692,0.137113405 GOTERM_BP_DIRECT,GO:0009725~response to hormone,18,0.484001076,0.003913402,"H3F3B, H3F3A, SORD, FHL2, DHCR24, SREBF2, TXN2, ACAT1, GCLC, MAT2A, OXCT1, LONP1, AKT1, UQCRFS1, CD38, PTK2B, ANG, TAC1",3331,48,18082,2.035649955,1,0.144861686,0.14208423 GOTERM_BP_DIRECT,GO:1900026~positive regulation of substrate adhesion-dependent cell spreading,14,0.376445281,0.003927496,"APOA1, CIB1, CRKL, DNM2, CDC42, NET1, ARPC2, C1QBP, MYADM, RAC1, CALR, CRK, DBN1, S100A10",3331,33,18082,2.302957525,1,0.144861686,0.14208423 GOTERM_BP_DIRECT,GO:0000027~ribosomal large subunit assembly,12,0.322667384,0.004097509,"MRPL20, RPL5, RPL3, RPL10, RPL12, RPL11, MRTO4, RPL24, RPL23A, BRIX1, RPL6, MRPL11",3331,26,18082,2.505415329,1,0.148170865,0.145329962 GOTERM_BP_DIRECT,GO:0030150~protein import into mitochondrial matrix,9,0.242000538,0.004115803,"TOMM40, GRPEL1, GRPEL2, TOMM7, TIMM17B, TIMM44, TOMM20, TOMM22, TIMM50",3331,16,18082,3.053474932,1,0.148170865,0.145329962 GOTERM_BP_DIRECT,"GO:0000380~alternative mRNA splicing, via spliceosome",9,0.242000538,0.004115803,"HNRNPM, RBM17, MBNL1, SFPQ, KDM1A, ESRP1, SRSF1, SRSF6, PQBP1",3331,16,18082,3.053474932,1,0.148170865,0.145329962 GOTERM_BP_DIRECT,GO:0060009~Sertoli cell development,9,0.242000538,0.004115803,"CST3, ADRM1, AKAP9, ATRX, MAP7, HSD17B4, SDC1, SOX9, FNDC3A",3331,16,18082,3.053474932,1,0.148170865,0.145329962 GOTERM_BP_DIRECT,GO:0010469~regulation of receptor activity,7,0.18822264,0.004128188,"PPP2CA, UBE2I, PLAU, SERPINE1, PPP2R5B, PCSK9, MUC4",3331,10,18082,3.799879916,1,0.148170865,0.145329962 GOTERM_BP_DIRECT,GO:0006260~DNA replication,36,0.968002151,0.004179364,"2810417H13RIK, PCNA, MCM7, MCMDC2, PRIM1, TNFAIP1, TBRG1, POLB, CHTF8, RBBP4, POLD1, POLD2, REV3L, RBBP6, RBBP7, CDT1, RMI2, RRM1, RFC1, LIG1, RPA2, WRNIP1, SSRP1, ADRA2A, DNAJC2, NFIA, NASP, NFIB, RPA3, NFIC, MCM3, MCM5, MCM6, SSBP1, TOP1, MCM2",3331,123,18082,1.588799965,1,0.149205526,0.146344785 GOTERM_BP_DIRECT,GO:0007264~small GTPase mediated signal transduction,61,1.640225867,0.004422728,"RAB3B, RAB9, ARF3, ARF4, RAB3C, ARF1, GDI1, RAB3D, DOCK7, GDI2, ARHGAP1, RAB43, YWHAQ, RAC1, ARL5A, RAB8A, RAB2A, RALBP1, RHOG, RHOC, RHOA, RAB33B, ARL4A, RHOU, ARF5, RAPGEF4, ARF6, ARL8B, RASL12, RALA, RAB1B, ARL3, ARHGAP18, AGAP1, RAP1B, GNA13, CDC42, RAP1A, RRAS, RAB25, RAB24, G3BP2, RAB6A, RALGDS, RAB4A, RAB4B, RAB27A, RAB27B, RAB11A, RAB11B, RAB10, DAB1, RAB14, RAB15, DNAJA3, SRPRB, KRAS, RAB17, RGL2, RAB5A, RAN",3331,236,18082,1.403103359,1,0.157053879,0.15404266 GOTERM_BP_DIRECT,GO:0031018~endocrine pancreas development,16,0.430223178,0.004622132,"PKLR, ONECUT2, HNF4G, SLC2A2, MYT1, NEUROD1, RFX6, HNF4A, HES1, SOX9, BAK1, INSM1, SOX4, FOXA3, NKX2-2, FOXA2",3331,41,18082,2.118399953,1,0.163266404,0.160136071 GOTERM_BP_DIRECT,GO:0010501~RNA secondary structure unwinding,17,0.457112127,0.004838188,"DDX17, EIF4A2, DDX39, EIF4A1, DDX6, DDX5, DDX3X, DDX27, DDX46, DDX24, DDX1, EIF4A3, DDX21, DDX54, DDX19B, DDX39B, DHX36",3331,45,18082,2.050728844,1,0.168535786,0.165304423 GOTERM_BP_DIRECT,GO:0018027~peptidyl-lysine dimethylation,5,0.134444743,0.004897535,"SETD3, EHMT2, SETD7, SMYD2, EHMT1",3331,5,18082,5.42839988,1,0.168535786,0.165304423 GOTERM_BP_DIRECT,GO:0042921~glucocorticoid receptor signaling pathway,5,0.134444743,0.004897535,"NEDD4, PTGES3, ARID1A, NR3C1, YWHAH",3331,5,18082,5.42839988,1,0.168535786,0.165304423 GOTERM_BP_DIRECT,GO:0045040~protein import into mitochondrial outer membrane,5,0.134444743,0.004897535,"HSP90AA1, SAMM50, HSPA4, TOMM7, TOMM22",3331,5,18082,5.42839988,1,0.168535786,0.165304423 GOTERM_BP_DIRECT,GO:0075525~viral translational termination-reinitiation,5,0.134444743,0.004897535,"EIF3L, EIF3G, EIF3D, EIF3A, EIF3B",3331,5,18082,5.42839988,1,0.168535786,0.165304423 GOTERM_BP_DIRECT,GO:0006164~purine nucleotide biosynthetic process,10,0.268889486,0.005683702,"ADSL, ATIC, MTHFD1, IMPDH1, IMPDH2, HPRT, GART, ADSS, PAICS, PRPS1L3",3331,20,18082,2.71419994,1,0.192263771,0.188577467 GOTERM_BP_DIRECT,GO:0009116~nucleoside metabolic process,10,0.268889486,0.005683702,"PRPSAP1, PRPS2, ATIC, PNP, PNP2, PPAT, HPRT, UPP1, PRPS1L3, APRT",3331,20,18082,2.71419994,1,0.192263771,0.188577467 GOTERM_BP_DIRECT,GO:0006406~mRNA export from nucleus,15,0.40333423,0.005702251,"EIF5A, DDX39, ENY2, CHTOP, SHFM1, THOC3, THOC7, ALKBH5, DDX19B, DDX39B, NUP85, SARNP, HNRNPA2B1, NUP88, SRSF10",3331,38,18082,2.142789426,1,0.192263771,0.188577467 GOTERM_BP_DIRECT,GO:0070534~protein K63-linked ubiquitination,15,0.40333423,0.005702251,"UBE2B, ZFP91, WWP2, UBE2G1, PRPF19, RNF4, RNF5, RNF126, HECTD1, UBE2S, NEDD4, UBE2N, UBE2V2, TRIM27, UBE2V1",3331,38,18082,2.142789426,1,0.192263771,0.188577467 GOTERM_BP_DIRECT,GO:0070979~protein K11-linked ubiquitination,12,0.322667384,0.005779419,"ANAPC13, UBE2W, UBE2B, UBE2S, UBE2C, UBE2D3, ANAPC5, RNF4, ANAPC1, ANAPC2, UBE2L3, ANAPC11",3331,27,18082,2.412622169,1,0.192916996,0.189218168 GOTERM_BP_DIRECT,GO:2001243~negative regulation of intrinsic apoptotic signaling pathway,12,0.322667384,0.005779419,"IVNS1ABP, NDUFA13, DDX3X, HDAC1, SRC, PPIF, NDUFS3, VDAC2, GCG, BCL2L2, HERPUD1, MCL1",3331,27,18082,2.412622169,1,0.192916996,0.189218168 GOTERM_BP_DIRECT,GO:0031175~neuron projection development,39,1.048668997,0.006098859,"ITGB1, APP, BTG2, DOCK7, PTEN, PRICKLE2, PTPRK, IGF1R, PQBP1, CAPZB, BLOC1S1, CDH1, CLMN, MICALL2, PTK2B, PHGDH, STX3, ARFGEF1, MKL2, TMEM30A, UNC5A, RYK, PRMT1, UBE4B, RAB11A, MANF, CAMSAP3, GNAO1, EHD1, CD24A, APC, VAPA, NEDD4, TBC1D24, ULK1, ATXN10, CD44, FRYL, CUL4B",3331,139,18082,1.523076225,1,0.202567089,0.198683238 GOTERM_BP_DIRECT,GO:0032024~positive regulation of insulin secretion,18,0.484001076,0.006276649,"PFKFB2, TCF7L2, MGEA5, BAD, GLRX, AACS, PTBP1, GLUD1, PSMD9, TRPM2, RBP4, SERP1, UCN3, CD38, TARDBP, GLUL, SOX4, PCK2",3331,50,18082,1.954223957,1,0.207440132,0.20346285 GOTERM_BP_DIRECT,GO:1990090~cellular response to nerve growth factor stimulus,13,0.349556332,0.006500803,"APP, KIDINS220, CIB1, CSNK1D, EHD1, RAP1A, ARPC3, ID1, RPS3, AKT1, HES1, TAC1, BPTF",3331,31,18082,2.276425756,1,0.213739019,0.209640967 GOTERM_BP_DIRECT,GO:0010867~positive regulation of triglyceride biosynthetic process,9,0.242000538,0.00653127,"CTDNEP1, SREBF1, TCF7L2, DGAT2, DGAT1, ACSL6, APOC3, ACSL5, LDLR",3331,17,18082,2.87385876,1,0.213739019,0.209640967 GOTERM_BP_DIRECT,GO:0030833~regulation of actin filament polymerization,11,0.295778435,0.006967671,"HAX1, FCHSD2, ARPC2, ARPC3, ARPC1B, ARPC1A, ARPC5L, ARHGAP18, ARPC5, PAK3, DBN1",3331,24,18082,2.488016612,1,0.221877894,0.217623794 GOTERM_BP_DIRECT,GO:0006950~response to stress,14,0.376445281,0.007037507,"TRAP1, NPM1, SMG1, HSP90AA1, HSP90AB1, GADD45A, MINK1, AHSA1, GADD45G, HSP90B1, MAPK13, UCN3, MAPKAPK2, MAP4K4",3331,35,18082,2.171359952,1,0.221877894,0.217623794 GOTERM_BP_DIRECT,GO:1904628~cellular response to phorbol 13-acetate 12-myristate,6,0.161333692,0.007203686,"ARPC2, CDK4, MYC, RPLP0, ZFP36L2, ZFP36L1",3331,8,18082,4.07129991,1,0.221877894,0.217623794 GOTERM_BP_DIRECT,GO:0006012~galactose metabolic process,6,0.161333692,0.007203686,"GALE, B4GALT1, GALT, GALM, GALK2, GALK1",3331,8,18082,4.07129991,1,0.221877894,0.217623794 GOTERM_BP_DIRECT,GO:0045542~positive regulation of cholesterol biosynthetic process,6,0.161333692,0.007203686,"SEC14L2, SREBF1, FDPS, POR, SCP2, FGF1",3331,8,18082,4.07129991,1,0.221877894,0.217623794 GOTERM_BP_DIRECT,GO:0010216~maintenance of DNA methylation,6,0.161333692,0.007203686,"USP7, DNMT1, UHRF1, KCNQ1OT1, DNMT3A, CTCF",3331,8,18082,4.07129991,1,0.221877894,0.217623794 GOTERM_BP_DIRECT,GO:0010918~positive regulation of mitochondrial membrane potential,6,0.161333692,0.007203686,"GSK3B, STOML2, TMEM135, VCP, BAD, MYC",3331,8,18082,4.07129991,1,0.221877894,0.217623794 GOTERM_BP_DIRECT,GO:0060992~response to fungicide,6,0.161333692,0.007203686,"KDM6B, KDM1A, SRD5A1, EHMT2, EHMT1, HIF1A",3331,8,18082,4.07129991,1,0.221877894,0.217623794 GOTERM_BP_DIRECT,GO:0032872~regulation of stress-activated MAPK cascade,6,0.161333692,0.007203686,"MAP2K2, GSTP1, PRDX1, NBR1, MAPK1, MAPK3",3331,8,18082,4.07129991,1,0.221877894,0.217623794 GOTERM_BP_DIRECT,GO:0006475~internal protein amino acid acetylation,6,0.161333692,0.007203686,"NAA10, MDH2, EHHADH, EP300, ASL, TXNL4A",3331,8,18082,4.07129991,1,0.221877894,0.217623794 GOTERM_BP_DIRECT,GO:0033572~transferrin transport,6,0.161333692,0.007203686,"SNX3, TFRC, REP15, CLTC, DNM2, RAB11B",3331,8,18082,4.07129991,1,0.221877894,0.217623794 GOTERM_BP_DIRECT,GO:0017148~negative regulation of translation,23,0.618445819,0.007213741,"GRB7, BTG2, TIA1, DDX3X, MVK, EIF4A3, IREB2, RPL13A, PRKCA, EPRS, TOB1, GIGYF2, SYNCRIP, ILF3, CNOT1, CAPRIN1, RPS3, EIF4EBP1, ANG, CALR, EIF4E2, PAIP2, GAPDH",3331,71,18082,1.758495736,1,0.221877894,0.217623794 GOTERM_BP_DIRECT,GO:0072583~clathrin-mediated endocytosis,8,0.215111589,0.007278499,"CANX, CLTB, HIP1R, CLTA, FNBP1L, DLL1, DNM1, PICALM",3331,14,18082,3.101942789,1,0.221877894,0.217623794 GOTERM_BP_DIRECT,GO:0032469~endoplasmic reticulum calcium ion homeostasis,8,0.215111589,0.007278499,"SELK, ITPR1, ATP2A2, TMBIM6, PSEN1, TMCO1, HERPUD1, GRINA",3331,14,18082,3.101942789,1,0.221877894,0.217623794 GOTERM_BP_DIRECT,GO:0051489~regulation of filopodium assembly,8,0.215111589,0.007278499,"CDC42, TRPM2, CLN3, MYO10, RAB17, RAB5A, DBN1, ARF6",3331,14,18082,3.101942789,1,0.221877894,0.217623794 GOTERM_BP_DIRECT,GO:0016070~RNA metabolic process,7,0.18822264,0.007673698,"DUSP11, POP5, RNASEH2A, XRN2, DDX54, TSN, PTBP3",3331,11,18082,3.454436287,1,0.22870362,0.224318649 GOTERM_BP_DIRECT,GO:0060416~response to growth hormone,7,0.18822264,0.007673698,"CPS1, RBBP4, SRD5A1, IRF1, NME2, AKT1, CACYBP",3331,11,18082,3.454436287,1,0.22870362,0.224318649 GOTERM_BP_DIRECT,GO:0090161~Golgi ribbon formation,7,0.18822264,0.007673698,"GOLGA2, PRMT5, GOLPH3, STX16, MYO18A, GCC2, OPTN",3331,11,18082,3.454436287,1,0.22870362,0.224318649 GOTERM_BP_DIRECT,GO:1990440~positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress,7,0.18822264,0.007673698,"ATF6B, CREB3L3, CREB3L1, TRP53, ATF6, ATF3, ATF4",3331,11,18082,3.454436287,1,0.22870362,0.224318649 GOTERM_BP_DIRECT,GO:0006646~phosphatidylethanolamine biosynthetic process,7,0.18822264,0.007673698,"CHKB, PCYT2, CHKA, ETNK1, EPT1, CEPT1, PISD",3331,11,18082,3.454436287,1,0.22870362,0.224318649 GOTERM_BP_DIRECT,GO:0048538~thymus development,19,0.510890024,0.007800348,"MAP2K2, CITED2, ADRM1, NFATC3, PSEN1, GATA3, PBX1, TGFBR1, CRKL, PRDX2, CCNB2, APC, MYB, CTNNB1, MAPK1, HES1, JARID2, MAPK3, EPHB3",3331,55,18082,1.875265413,1,0.230420889,0.226002993 GOTERM_BP_DIRECT,GO:0034613~cellular protein localization,19,0.510890024,0.007800348,"CD63, PRKCI, EXOC8, AXIN2, PRPF19, PRKCZ, CDC42, SLC9A3R1, NIPBL, TMEM33, SUMO2, CTNNA1, CTNNB1, ABL2, LAMTOR2, LAMTOR1, LAMTOR3, OPTN, RAN",3331,55,18082,1.875265413,1,0.230420889,0.226002993 GOTERM_BP_DIRECT,GO:0060548~negative regulation of cell death,25,0.672223716,0.00801757,"REG3B, MCFD2, PARK7, RNF4, CST3, MYC, AGR2, EP300, ABCB1A, SOX4, ATG5, CTSB, BNIP3L, HSPA4, BNIP3, PTGES3, STAT3, CACYBP, RHOA, CHMP2A, PICK1, CHMP4B, SRSF6, OGT, NFE2L2",3331,80,18082,1.696374962,1,0.235794261,0.23127334 GOTERM_BP_DIRECT,GO:0006970~response to osmotic stress,10,0.268889486,0.008342611,"ATF2, TSC22D4, NFAT5, MAP7, SORD, SLC2A1, PTK2B, LRRC8A, EGFR, MAPK13",3331,21,18082,2.584952324,1,0.242153341,0.237510497 GOTERM_BP_DIRECT,GO:0032435~negative regulation of proteasomal ubiquitin-dependent protein catabolic process,10,0.268889486,0.008342611,"BAG6, SDCBP, SMARCC1, UBXN1, HSP90AB1, TAF9, PBK, WAC, PARK7, N4BP1",3331,21,18082,2.584952324,1,0.242153341,0.237510497 GOTERM_BP_DIRECT,GO:0051412~response to corticosterone,10,0.268889486,0.008342611,"CDKN1A, MAOB, UCN3, CCND1, FOSB, PEBP1, CALM3, FOS, CALM1, CALM2",3331,21,18082,2.584952324,1,0.242153341,0.237510497 GOTERM_BP_DIRECT,GO:0007032~endosome organization,13,0.349556332,0.00868811,"EXOC8, VPS33B, FAM109A, A230046K03RIK, DNM1, FAM160A2, HOOK2, TMEM127, CHMP2B, PIK3C3, LAMTOR1, RAB5A, PLEKHJ1",3331,32,18082,2.205287451,1,0.25109015,0.246275959 GOTERM_BP_DIRECT,GO:0051592~response to calcium ion,22,0.59155687,0.008899347,"RANBP1, AHCYL1, GDI1, BAD, DUSP1, PEF1, PDCD6, ANXA5, MTTP, PEBP1, ITPR3, THBS1, EGFR, PPP3CA, CCND1, S100A16, HNRNPD, SDC1, TXNIP, EP300, PTK2B, SEC31A",3331,68,18082,1.75624702,1,0.256086387,0.251176403 GOTERM_BP_DIRECT,GO:0006418~tRNA aminoacylation for protein translation,14,0.376445281,0.009192164,"WARS, VARS, SARS, TARS, EPRS, NARS, AIMP1, LARS2, QARS, KARS, RARS, MARS, GARS, IARS",3331,36,18082,2.111044398,1,0.263377205,0.258327432 GOTERM_BP_DIRECT,GO:0007005~mitochondrion organization,25,0.672223716,0.0094481,"DCTN6, CEBPA, STOML2, PRKAG1, PRKAG2, PARK7, PHB, PHB2, PRDX3, HMGCL, CHCHD2, MAN2A1, LONP1, SH3GLB1, CLUH, CXADR, PTCD2, PARP1, CHCHD10, MAPK14, SOD2, MAPK13, TMEM11, DNAJA3, PEX5",3331,81,18082,1.675432062,1,0.269553486,0.264385294 GOTERM_BP_DIRECT,GO:0031623~receptor internalization,15,0.40333423,0.009510817,"ITGB1, TFRC, CD81, CLTC, DNM1, DNM2, SNX1, GRK4, NEDD4, CXCR2, CD9, ULK1, EZR, RAMP1, PICALM",3331,40,18082,2.035649955,1,0.270188153,0.265007793 GOTERM_BP_DIRECT,GO:0008652~cellular amino acid biosynthetic process,11,0.295778435,0.009726529,"PYCRL, MTHFD1, PSAT1, ADI1, CTH, ASNS, PHGDH, PYCR2, ASL, ALDH18A1, OTC",3331,25,18082,2.388495947,1,0.274000649,0.268747192 GOTERM_BP_DIRECT,GO:0030218~erythrocyte differentiation,17,0.457112127,0.009727105,"HSPA9, THRA, ATPIF1, ADAR, GATA3, SMAD5, RPS14, MFSD7B, HEPH, RPS19, KIT, TCEA1, ACIN1, SFXN1, ZFPM1, NFE2L1, TMEM14C",3331,48,18082,1.922558291,1,0.274000649,0.268747192 GOTERM_BP_DIRECT,GO:0006103~2-oxoglutarate metabolic process,9,0.242000538,0.009882451,"GHR, IDH3G, IDH1, IDH2, GOT2, OGDH, IDH3B, DLD, IDH3A",3331,18,18082,2.71419994,1,0.277206909,0.271891978 GOTERM_BP_DIRECT,GO:0001824~blastocyst development,12,0.322667384,0.010727609,"EMG1, SMARCB1, DMBT1, PSMC3, ELF3, NASP, CDX2, PSMC4, DAD1, ATP1B1, CDK11B, TGFBR1",3331,29,18082,2.246234433,1,0.295940162,0.290266055 GOTERM_BP_DIRECT,GO:0006513~protein monoubiquitination,12,0.322667384,0.010727609,"UBE2W, RNF126, CDC34, TSG101, UBE2B, UBE2R2, CUL3, NEDD4, UBE2D3, TRIM25, UBE4B, RBX1",3331,29,18082,2.246234433,1,0.295940162,0.290266055 GOTERM_BP_DIRECT,GO:0097421~liver regeneration,12,0.322667384,0.010727609,"PRMT5, RAP1A, RPS16, CCND1, RPL32, MYC, UCP2, SRSF1, SRSF5, REG1, GFER, EGFR",3331,29,18082,2.246234433,1,0.295940162,0.290266055 GOTERM_BP_DIRECT,GO:0043484~regulation of RNA splicing,12,0.322667384,0.010727609,"CLK1, MBNL1, SON, MBNL2, AHNAK, HNRNPH1, CELF1, SNRNP70, ESRP1, HNRNPF, PQBP1, CLK2",3331,29,18082,2.246234433,1,0.295940162,0.290266055 GOTERM_BP_DIRECT,GO:0006275~regulation of DNA replication,8,0.215111589,0.011502585,"ANKRD17, PCNA, EHMT2, GMNN, ID3, NUCKS1, RBBP6, SMC3",3331,15,18082,2.895146603,1,0.312159584,0.3061745 GOTERM_BP_DIRECT,GO:0043149~stress fiber assembly,8,0.215111589,0.011502585,"ITGB1, SRC, CUL3, ZYX, PTK2B, ARRB1, TNFAIP1, RHOA",3331,15,18082,2.895146603,1,0.312159584,0.3061745 GOTERM_BP_DIRECT,GO:0006878~cellular copper ion homeostasis,8,0.215111589,0.011502585,"PRNP, APP, ARF1, SLC31A1, APLP2, SLC11A2, COMMD1, ATOX1",3331,15,18082,2.895146603,1,0.312159584,0.3061745 GOTERM_BP_DIRECT,GO:0006376~mRNA splice site selection,8,0.215111589,0.011502585,"MBNL1, RBMXL1, CELF1, YTHDC1, LUC7L3, SRSF6, SRSF10, LUC7L2",3331,15,18082,2.895146603,1,0.312159584,0.3061745 GOTERM_BP_DIRECT,GO:0007346~regulation of mitotic cell cycle,14,0.376445281,0.011830085,"CDC123, CDKN1A, PLK1, GBF1, CKS1B, SDCBP, MYC, RPA3, CKS2, BIRC5, PIM3, PIM2, SAE1, CDK5RAP3",3331,37,18082,2.053989144,1,0.317659366,0.311568833 GOTERM_BP_DIRECT,GO:0009058~biosynthetic process,14,0.376445281,0.011830085,"PBLD1, ALAS1, PCYT2, GOT2, GPT, GCAT, PBLD2, GMPPB, SPTLC1, SPTLC2, FASN, GMPPA, GART, FDFT1",3331,37,18082,2.053989144,1,0.317659366,0.311568833 GOTERM_BP_DIRECT,GO:0043171~peptide catabolic process,10,0.268889486,0.01184799,"NPEPPS, ENPEP, RNPEPL1, ACY1, CPQ, ANPEP, CPE, TPP1, LTA4H, CNDP2",3331,22,18082,2.467454491,1,0.317659366,0.311568833 GOTERM_BP_DIRECT,GO:0031397~negative regulation of protein ubiquitination,15,0.40333423,0.012045691,"UBXN1, ARRB1, PARK7, GTPBP4, DNAJA1, GCLC, GNL3L, RPS3, TSPO, CHP1, OGT, VPS28, SOX4, N4BP1, ATG5",3331,41,18082,1.985999956,1,0.320386595,0.314243772 GOTERM_BP_DIRECT,GO:0007017~microtubule-based process,15,0.40333423,0.012045691,"TUBAL3, DCTN3, DYNLL1, TUBB4B, DYNLL2, TUBA4A, TUBA1C, TUBA1B, TUBB5, TUBA1A, MAP1B, KIF5B, XRN2, MAP3K11, PAFAH1B1",3331,41,18082,1.985999956,1,0.320386595,0.314243772 GOTERM_BP_DIRECT,GO:0033138~positive regulation of peptidyl-serine phosphorylation,23,0.618445819,0.012097076,"PPP1R15A, TXN1, GSK3B, GSK3A, DOCK7, ARAF, ARRB1, GCG, MIF, PARK7, VEGFA, CDC42, PAK1, HAX1, PDCD10, AKAP9, SPRY2, AKT1, PHIP, SMYD3, FNIP1, GAS6, CD44",3331,74,18082,1.687205368,1,0.320476495,0.314331949 GOTERM_BP_DIRECT,GO:0046931~pore complex assembly,5,0.134444743,0.012545538,"GSDMD, CCT3, BAD, ANO6, CCT8",3331,6,18082,4.523666567,1,0.32462794,0.318403797 GOTERM_BP_DIRECT,GO:1901030~positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway,5,0.134444743,0.012545538,"GSK3B, GSK3A, ATPIF1, HIP1R, BOK",3331,6,18082,4.523666567,1,0.32462794,0.318403797 GOTERM_BP_DIRECT,GO:0000056~ribosomal small subunit export from nucleus,5,0.134444743,0.012545538,"RPS15, NPM1, XPO1, NUP88, RAN",3331,6,18082,4.523666567,1,0.32462794,0.318403797 GOTERM_BP_DIRECT,GO:0006189~'de novo' IMP biosynthetic process,5,0.134444743,0.012545538,"ADSL, ATIC, PPAT, GART, PAICS",3331,6,18082,4.523666567,1,0.32462794,0.318403797 GOTERM_BP_DIRECT,GO:0035020~regulation of Rac protein signal transduction,5,0.134444743,0.012545538,"CRK, OGT, SSX2IP, ARF6, DNM2",3331,6,18082,4.523666567,1,0.32462794,0.318403797 GOTERM_BP_DIRECT,GO:0045047~protein targeting to ER,5,0.134444743,0.012545538,"SPCS2, SPCS1, PMM2, SRP68, SRP14",3331,6,18082,4.523666567,1,0.32462794,0.318403797 GOTERM_BP_DIRECT,"GO:0006123~mitochondrial electron transport, cytochrome c to oxygen",7,0.18822264,0.012978165,"COX8A, COX4I1, CYCS, COX5B, COX6A1, COX7C, COX5A",3331,12,18082,3.166566597,1,0.33069554,0.324355062 GOTERM_BP_DIRECT,"GO:0006120~mitochondrial electron transport, NADH to ubiquinone",7,0.18822264,0.012978165,"NDUFB9, NDUFA7, NDUFB8, NDUFS6, NDUFC2, NDUFV2, DLD",3331,12,18082,3.166566597,1,0.33069554,0.324355062 GOTERM_BP_DIRECT,GO:0045056~transcytosis,7,0.18822264,0.012978165,"SRC, USO1, MAL2, CHP1, VPS35, RAB17, MFSD2A",3331,12,18082,3.166566597,1,0.33069554,0.324355062 GOTERM_BP_DIRECT,GO:0045899~positive regulation of RNA polymerase II transcriptional preinitiation complex assembly,7,0.18822264,0.012978165,"PSMC5, PSMC6, CAND1, PSMC3, PSMC4, PSMC1, GTF2F2",3331,12,18082,3.166566597,1,0.33069554,0.324355062 GOTERM_BP_DIRECT,GO:0001836~release of cytochrome c from mitochondria,11,0.295778435,0.013244667,"FIS1, JUN, BAD, TRP53, BAX, CCK, BAK1, SOD2, MFF, BOK, TIMM50",3331,26,18082,2.296630718,1,0.336203039,0.329756965 GOTERM_BP_DIRECT,GO:0009790~embryo development,24,0.645334767,0.013565978,"TPI1, TAF10, APLP2, ATP5A1, TPM1, SMARCA5, EHMT1, UBR3, TNFAIP1, PSEN1, HMGCR, TGFBR1, CKS1B, FOXP1, BAG6, HMGCL, RBP4, RAB14, ELF3, DNAJA3, CKS2, BIRC5, KIF1B, GTF2I",3331,79,18082,1.649134141,1,0.340313956,0.333789063 GOTERM_BP_DIRECT,GO:0006782~protoporphyrinogen IX biosynthetic process,6,0.161333692,0.013763446,"ALAD, ALAS1, UROD, UROS, IREB2, CPOX",3331,9,18082,3.618933253,1,0.340313956,0.333789063 GOTERM_BP_DIRECT,GO:0006002~fructose 6-phosphate metabolic process,6,0.161333692,0.013763446,"PFKL, GFPT1, TALDO1, FBP1, PFKP, FBP2",3331,9,18082,3.618933253,1,0.340313956,0.333789063 GOTERM_BP_DIRECT,GO:0044070~regulation of anion transport,6,0.161333692,0.013763446,"AHCYL1, TTYH1, VDAC3, VDAC2, VDAC1, RAB11B",3331,9,18082,3.618933253,1,0.340313956,0.333789063 GOTERM_BP_DIRECT,GO:2000146~negative regulation of cell motility,6,0.161333692,0.013763446,"SLC9A3R1, CTNNA1, PIN1, FBLN1, SPINT2, GATA3",3331,9,18082,3.618933253,1,0.340313956,0.333789063 GOTERM_BP_DIRECT,GO:0034332~adherens junction organization,6,0.161333692,0.013763446,"DSP, CDC42, CDH1, SRC, CTNNB1, CSK",3331,9,18082,3.618933253,1,0.340313956,0.333789063 GOTERM_BP_DIRECT,GO:0039702~viral budding via host ESCRT complex,6,0.161333692,0.013763446,"PDCD6IP, CHMP1B, CHMP2B, CHMP2A, CHMP4B, CHMP6",3331,9,18082,3.618933253,1,0.340313956,0.333789063 GOTERM_BP_DIRECT,GO:0043627~response to estrogen,23,0.618445819,0.014213498,"DTYMK, HSP90AA1, ABCC2, SRD5A1, CITED2, PTPRN, ARPC1B, GATA6, APOA1, ASH2L, GATA3, TGFBR1, AQP1, HSPD1, CD24A, KRT19, CCND1, CTNNA1, CTNNB1, MAPK1, TRIM25, EP300, ALDOA",3331,75,18082,1.664709297,1,0.350145069,0.343431683 GOTERM_BP_DIRECT,GO:0033539~fatty acid beta-oxidation using acyl-CoA dehydrogenase,9,0.242000538,0.014357731,"ACADVL, ACADL, ACOX1, ETFA, ACADM, ETFB, ACAD11, ACADS, ACADSB",3331,19,18082,2.571347312,1,0.351107005,0.344375175 GOTERM_BP_DIRECT,GO:0043409~negative regulation of MAPK cascade,9,0.242000538,0.014357731,"NLRP6, APC, DUSP1, RNF149, DAG1, PEBP1, ASH1L, DUSP16, IGF1R",3331,19,18082,2.571347312,1,0.351107005,0.344375175 GOTERM_BP_DIRECT,GO:0071333~cellular response to glucose stimulus,22,0.59155687,0.01486678,"XBP1, GPX1, NME2, APOC3, CYBA, AACS, IGF1R, PPP2CA, NEUROD1, PPP3CA, MLXIPL, GCLC, RAP1A, UCP2, PDK3, GCLM, SLC29A1, GAS6, PRKACA, OGT, SOX4, PCK2",3331,71,18082,1.682039399,1,0.36222855,0.355283485 GOTERM_BP_DIRECT,GO:0042594~response to starvation,14,0.376445281,0.015016559,"ADSL, CAD, GCG, SSTR1, AACS, ACAT1, HMGCL, ZFP36, UCN3, CPS1, OXCT1, ULK1, ACADM, LRP11",3331,38,18082,1.999936798,1,0.364547443,0.357557917 GOTERM_BP_DIRECT,GO:0006919~activation of cysteine-type endopeptidase activity involved in apoptotic process,21,0.564667921,0.015518994,"MTCH1, EGLN3, VCP, CDKN1B, NLRP1A, BAD, PDCD6, HIP1R, CCK, HSPD1, PYCARD, DAP, AIFM1, FAM162A, MYC, BAX, PDCD2, ANP32B, BAK1, XDH, BOK",3331,67,18082,1.701438768,1,0.375379732,0.368182518 GOTERM_BP_DIRECT,GO:0034599~cellular response to oxidative stress,20,0.537778973,0.016161144,"TXN1, XBP1, SRXN1, PARP1, HDAC1, PRKCD, TXNL1, NME2, ATP2A2, PYCR2, PARK7, TXN2, PRDX3, PRDX2, ALDH3B1, G6PDX, LONP1, NFE2L1, VIMP, NFE2L2",3331,63,18082,1.723301549,1,0.389501067,0.382033101 GOTERM_BP_DIRECT,GO:0045070~positive regulation of viral genome replication,10,0.268889486,0.01634351,"TOP2A, DDB1, DDX3X, LARP1, ADAR, PKN2, PABPC1, PPIA, PPID, TARBP2",3331,23,18082,2.360173861,1,0.392479409,0.384954339 GOTERM_BP_DIRECT,GO:0042127~regulation of cell proliferation,56,1.505781124,0.016595157,"B4GALT1, CDKN1B, TES, CD81, HP1BP3, SERPINE1, CIB1, NR3C1, SAT1, PLAU, SOX9, JARID2, JUNB, JAK1, MMP7, MIF, GNL3, TNFRSF1A, DUSP22, RNF126, CFDP1, TXNIP, JTB, ATF5, GUCY2C, CEBPA, DNMT1, SRC, CDCA7, HIF1A, NDRG1, EGFR, BAG6, CTNNA1, PTK2B, ABL2, STAT6, S100A11, ESRRA, EGLN3, JUND, JUP, MBD2, PLA2G2A, KLF4, PBX1, CDK4, RPA3, TRP53, SPRY2, PIN1, CTNNB1, DHCR7, LTBR, LGR5, FRK",3331,227,18082,1.339164728,1,0.397094141,0.389480592 GOTERM_BP_DIRECT,GO:0001701~in utero embryonic development,71,1.909115354,0.01693076,"ITGB1, KDM1A, PRKCSH, CITED2, CHD8, PITPNB, CHD7, KEAP1, PLOD3, BRK1, ADAR, YBX1, YBX3, GPI1, FLCN, TRIM28, CDH1, MYC, MYB, RESP18, TMED2, JUNB, MKL2, MBNL1, KDM2A, PRMT1, TPM1, EPN1, TGFBR1, MTSS1, FOXP1, MYH9, EIF4E2, LY6E, DDX5, ANKRD11, CUL3, SRSF1, GATA6, UBR3, GATA3, ASCL2, DLL1, GNA13, CCNB2, RXRA, MAN2A1, MGAT1, RBBP6, HES1, APOB, WDTC1, MBD3, BTF3, UBE2B, USP9X, KIDINS220, EIF2S2, VEGFA, GATAD2A, MFSD7B, CR1L, SP1, TRP53, NMT1, CDK2AP1, CTNNB1, APBA3, SEC24D, SEC24C, FOXA2",3331,299,18082,1.289018032,1,0.403677696,0.39593792 GOTERM_BP_DIRECT,GO:0051091~positive regulation of sequence-specific DNA binding transcription factor activity,30,0.806668459,0.017056159,"FOXA1, ATF2, GTF2A2, BEX2, SMARCB1, KDM1A, PTEN, PARK7, PHB2, PYCARD, NEUROD1, TRIM8, PPP3CA, AKT1, TRIM25, EP300, TRIM27, HMGN3, NKX2-2, FZD1, UBE2I, JUP, PPP2R5B, ARID5B, RGCC, KIT, JMY, CTNNB1, TCF3, TRIM31",3331,107,18082,1.521981275,1,0.405220336,0.397450983 GOTERM_BP_DIRECT,GO:0006401~RNA catabolic process,8,0.215111589,0.01724786,"ISG20, RNASEH2C, EXOSC5, RNASEH2A, ANG4, SKIV2L, SKIV2L2, SND1",3331,16,18082,2.71419994,1,0.405446166,0.397672482 GOTERM_BP_DIRECT,GO:1903543~positive regulation of exosomal secretion,8,0.215111589,0.01724786,"SMPD3, SDCBP, TSG101, PDCD6IP, SDC4, MYO5B, CHMP2A, SDC1",3331,16,18082,2.71419994,1,0.405446166,0.397672482 GOTERM_BP_DIRECT,GO:0000920~cell separation after cytokinesis,8,0.215111589,0.01724786,"PDCD6IP, CHMP1B, CHMP1A, CHMP2B, CHMP2A, CHMP4B, CHMP6, CHMP5",3331,16,18082,2.71419994,1,0.405446166,0.397672482 GOTERM_BP_DIRECT,GO:0071902~positive regulation of protein serine/threonine kinase activity,11,0.295778435,0.01763599,"PPP2CA, MAP2K2, HSP90AB1, CAB39, PDCD10, SRC, PIH1D1, CIB1, HIGD1A, RHOA, LTF",3331,27,18082,2.211570321,1,0.411670874,0.403777843 GOTERM_BP_DIRECT,GO:0006820~anion transport,11,0.295778435,0.01763599,"SLC4A7, SLC37A1, SLC22A18, VDAC3, VDAC2, LRRC8A, VDAC1, SLC4A2, SLC37A4, KCNN4, SLC4A4",3331,27,18082,2.211570321,1,0.411670874,0.403777843 GOTERM_BP_DIRECT,GO:0051591~response to cAMP,17,0.457112127,0.017890142,"SREBF1, JUN, JUND, PKLR, DUSP1, PTPRN, PEBP1, FOS, PIK3R1, MAT2A, NDUFS4, BSG, SDC1, FOSB, PTK2B, CDO1, JUNB",3331,51,18082,1.809466627,1,0.416148385,0.408169507 GOTERM_BP_DIRECT,GO:2000379~positive regulation of reactive oxygen species metabolic process,12,0.322667384,0.01839688,"EIF5A, CDKN1A, PLAU, GADD45A, TRP53, TSPO, PTK2B, ROMO1, MAPK14, THBS1, XDH, NFE2L2",3331,31,18082,2.101316083,1,0.423508865,0.415388863 GOTERM_BP_DIRECT,GO:0042771~intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator,12,0.322667384,0.01839688,"BAG6, PYCARD, CDKN1A, SNW1, TRP53, BCL3, DDIT4, SHISA5, RPS27L, EP300, NUPR1, HIPK1",3331,31,18082,2.101316083,1,0.423508865,0.415388863 GOTERM_BP_DIRECT,"GO:0000184~nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",12,0.322667384,0.01839688,"SMG1, RBM8A, NCBP2, EIF4A3, MAGOH, UPF3B, ETF1, RNPS1, EIF3E, PABPC1, GSPT1, PNRC2",3331,31,18082,2.101316083,1,0.423508865,0.415388863 GOTERM_BP_DIRECT,GO:0090002~establishment of protein localization to plasma membrane,15,0.40333423,0.018656341,"JUP, ROCK1, ROCK2, F11R, MPP5, TNFRSF1A, IFT20, TSPAN15, SLC9A3R1, EFR3A, TTC7, CDH1, PKP3, EZR, S100A10",3331,43,18082,1.893627865,1,0.427300231,0.419107536 GOTERM_BP_DIRECT,GO:0061025~membrane fusion,13,0.349556332,0.018756946,"NAPA, STX17, UBXN2A, STX16, USO1, STX7, VPS33B, DNM1, DNM2, VAMP8, CHP1, STX5A, STX3",3331,35,18082,2.016262813,1,0.427300231,0.419107536 GOTERM_BP_DIRECT,GO:0005977~glycogen metabolic process,14,0.376445281,0.018817596,"TCF7L2, GSK3B, GSK3A, G6PC, GAA, PRKAG2, PPP1CA, PPP1CB, PPP1R2, PPP1CC, GYS1, UGP2, AKT1, SLC37A4",3331,39,18082,1.948656367,1,0.427300231,0.419107536 GOTERM_BP_DIRECT,GO:0043085~positive regulation of catalytic activity,14,0.376445281,0.018817596,"PSENEN, HSPA8, ARF1, NPM1, BTG1, YWHAB, CIB1, PSEN1, SOD1, APH1A, CDC42, CLPS, MYC, SLC37A4",3331,39,18082,1.948656367,1,0.427300231,0.419107536 GOTERM_BP_DIRECT,GO:0010977~negative regulation of neuron projection development,20,0.537778973,0.019119162,"RAP1GAP2, GSK3B, PRKCSH, H2-K1, INPPL1, CIB1, RTN4, RHOA, ADCY6, PTPRG, INPP5J, HES1, VIM, FKBP4, B2M, H2-D1, ITM2C, PAFAH1B1, MAP4K4, RUNX1T1",3331,64,18082,1.696374962,1,0.432676364,0.424380592 GOTERM_BP_DIRECT,GO:0006509~membrane protein ectodomain proteolysis,9,0.242000538,0.020140417,"PSENEN, APH1A, BACE1, BACE2, RBMXL1, SPPL2A, DAG1, MYH9, PSEN1",3331,20,18082,2.442779946,1,0.45119941,0.442548493 GOTERM_BP_DIRECT,GO:0031333~negative regulation of protein complex assembly,9,0.242000538,0.020140417,"CDC42, GSK3B, DDX3X, STXBP1, EIF4EBP1, ULK1, DNAJC15, SVIP, PRKCZ",3331,20,18082,2.442779946,1,0.45119941,0.442548493 GOTERM_BP_DIRECT,GO:0000413~protein peptidyl-prolyl isomerization,9,0.242000538,0.020140417,"FKBP1A, PPIL1, PPIF, PPIG, FKBP4, PPIB, PPIA, PPID, NKTR",3331,20,18082,2.442779946,1,0.45119941,0.442548493 GOTERM_BP_DIRECT,GO:0043248~proteasome assembly,7,0.18822264,0.020398799,"PSMD8, PSMD4, SHFM1, ADRM1, POMP, ELP2, PSMG2",3331,13,18082,2.922984551,1,0.452433173,0.4437586 GOTERM_BP_DIRECT,GO:0006536~glutamate metabolic process,7,0.18822264,0.020398799,"GCLC, GOT2, ALDH18A1, NAGS, GGT1, GCLM, GLUL",3331,13,18082,2.922984551,1,0.452433173,0.4437586 GOTERM_BP_DIRECT,GO:0009303~rRNA transcription,7,0.18822264,0.020398799,"NPM1, RNASEK, MARS, TRP53, ANG, SIRT7, TOP1",3331,13,18082,2.922984551,1,0.452433173,0.4437586 GOTERM_BP_DIRECT,GO:0043433~negative regulation of sequence-specific DNA binding transcription factor activity,21,0.564667921,0.021401546,"EGLN1, TCF7L2, PRNP, THRA, KDM1A, CEBPG, RPL11, KEAP1, WWP2, KLF4, PHB2, IGF1R, SUMO1, HNF4A, BHLHE40, ID1, SPOP, ID3, GAS6, TRIB1, FOXA2",3331,69,18082,1.652121703,1,0.466441496,0.45749834 GOTERM_BP_DIRECT,GO:0046060~dATP metabolic process,4,0.107555795,0.02151947,"MGEA5, GUK1, AK2, AK3",3331,4,18082,5.42839988,1,0.466441496,0.45749834 GOTERM_BP_DIRECT,GO:1903553~positive regulation of extracellular exosome assembly,4,0.107555795,0.02151947,"SDCBP, PDCD6IP, SDC4, SDC1",3331,4,18082,5.42839988,1,0.466441496,0.45749834 GOTERM_BP_DIRECT,GO:0042776~mitochondrial ATP synthesis coupled proton transport,4,0.107555795,0.02151947,"STOML2, CYC1, ATP5O, COX5B",3331,4,18082,5.42839988,1,0.466441496,0.45749834 GOTERM_BP_DIRECT,GO:0001951~intestinal D-glucose absorption,4,0.107555795,0.02151947,"VIL1, SLC5A1, EZR, PLS1",3331,4,18082,5.42839988,1,0.466441496,0.45749834 GOTERM_BP_DIRECT,GO:0033499~galactose catabolic process via UDP-galactose,4,0.107555795,0.02151947,"GALE, GALT, GALM, GALK1",3331,4,18082,5.42839988,1,0.466441496,0.45749834 GOTERM_BP_DIRECT,GO:0031345~negative regulation of cell projection organization,4,0.107555795,0.02151947,"ITGB1, ITGA3, SPRY2, PTPRF",3331,4,18082,5.42839988,1,0.466441496,0.45749834 GOTERM_BP_DIRECT,GO:0051260~protein homooligomerization,49,1.317558483,0.021708538,"CEP57, APP, DGKD, TNFAIP1, FGFRL1, ALAD, CDH1, LONP1, ANXA6, REG1, GLUL, TGM2, CPT1A, ATPIF1, ANXA5, KCTD3, EEF1A1, CLDN3, RBMXL1, CLPP, PICK1, CHMP4B, KCTD12, OPTN, REG3B, CUTA, VCP, DERL1, AK3, ITPR3, MFF, ACAT1, NACC1, GSDMD, FIS1, PRNP, NPM1, GCH1, ST13, TAF10, TMEM120A, SOD2, TOR1B, EHD1, P2RX4, CHMP2A, AQP11, BAX, PAM",3331,197,18082,1.350211138,1,0.469016835,0.460024301 GOTERM_BP_DIRECT,GO:0060441~epithelial tube branching involved in lung morphogenesis,10,0.268889486,0.021969014,"FOXA1, CTSL, ESRP1, CTSZ, DAG1, CTNNB1, KRAS, SOX9, CTSD, FOXA2",3331,24,18082,2.261833283,1,0.470080565,0.461067637 GOTERM_BP_DIRECT,GO:0042273~ribosomal large subunit biogenesis,10,0.268889486,0.021969014,"ZFP622, RPL5, EBNA1BP2, NPM1, EIF6, NIP7, RPL11, RPL14, RPL35A, RPL7",3331,24,18082,2.261833283,1,0.470080565,0.461067637 GOTERM_BP_DIRECT,GO:0009987~cellular process,10,0.268889486,0.021969014,"GNAO1, APP, JUN, TUBB5, AMFR, MAP1B, CTNNB1, HDGF, JUNB, PPP1CA",3331,24,18082,2.261833283,1,0.470080565,0.461067637 GOTERM_BP_DIRECT,GO:0070936~protein K48-linked ubiquitination,16,0.430223178,0.022243612,"UBE2B, UBE2C, AMFR, UBE2D3, RNF6, UBE2G1, UBE2D2A, RNF4, MARCH6, RNF5, RNF126, CDC34, UBE2R2, PELI1, UBE2K, RNF187",3331,48,18082,1.809466627,1,0.474435634,0.465339205 GOTERM_BP_DIRECT,GO:0043524~negative regulation of neuron apoptotic process,41,1.102446894,0.022873237,"REG3B, BTG2, SET, HSP90AB1, ROCK1, HDAC1, SCT, STXBP1, CACNA1A, PSEN1, PARK7, HIF1A, HSPD1, GPI1, PRDX3, CLN3, FAM134B, PRDX2, PTK2B, BOK, PRKCI, JUN, NPM1, MT1, SOD2, RHOA, VEGFA, SOD1, TOX3, GCLC, DNAJC5, UBE2V2, PPT1, BIRC5, PIN1, BAX, KRAS, ADNP, GCLM, OPTN, LGMN",3331,160,18082,1.391027469,1,0.474769219,0.465666394 GOTERM_BP_DIRECT,GO:0009791~post-embryonic development,31,0.833557408,0.023065147,"IREB2, INPPL1, ITPR1, PSEN1, GATA3, GIGYF2, SLC8A1, SERP1, ASL, ACADM, APOB, SLC18A2, DDX17, TCF7L2, PLEKHA1, USP9X, ARID5B, ASH1L, SOD2, SEPP1, MYT1, IGF2R, RC3H2, TGFBR1, GNAQ, GNAS, BAX, ACO1, DHCR7, ATF5, LLGL2",3331,114,18082,1.476143827,1,0.474769219,0.465666394 GOTERM_BP_DIRECT,GO:0045773~positive regulation of axon extension,14,0.376445281,0.023298637,"RPL4, GSK3B, EIF2B2, RAB11A, GOLGA4, PAK1, MAP1B, MYO5B, EP300, ADNP, DBN1, EIF4G2, PAFAH1B1, ANAPC2",3331,40,18082,1.899939958,1,0.474769219,0.465666394 GOTERM_BP_DIRECT,GO:0006750~glutathione biosynthetic process,6,0.161333692,0.023398705,"GCLC, GSS, MGST2, HAGH, GGT1, GCLM",3331,10,18082,3.257039928,1,0.474769219,0.465666394 GOTERM_BP_DIRECT,GO:0006687~glycosphingolipid metabolic process,6,0.161333692,0.023398705,"HEXB, PSAP, KIT, MAP7, BAX, B4GALNT1",3331,10,18082,3.257039928,1,0.474769219,0.465666394 GOTERM_BP_DIRECT,GO:0006983~ER overload response,6,0.161333692,0.023398705,"PPP1R15B, GSK3B, HSPA5, TRP53, VIMP, TMCO1",3331,10,18082,3.257039928,1,0.474769219,0.465666394 GOTERM_BP_DIRECT,GO:0048679~regulation of axon regeneration,6,0.161333692,0.023398705,"MAP2K2, STK24, PTEN, KLF4, NEO1, PTPRF",3331,10,18082,3.257039928,1,0.474769219,0.465666394 GOTERM_BP_DIRECT,GO:0006884~cell volume homeostasis,6,0.161333692,0.023398705,"NPM1, CLNS1A, LRRC8A, KCNN4, SLC12A7, AQP1",3331,10,18082,3.257039928,1,0.474769219,0.465666394 GOTERM_BP_DIRECT,GO:0034063~stress granule assembly,6,0.161333692,0.023398705,"DYNC1H1, GRB7, DDX3X, CIRBP, PUM2, PQBP1",3331,10,18082,3.257039928,1,0.474769219,0.465666394 GOTERM_BP_DIRECT,GO:0006105~succinate metabolic process,6,0.161333692,0.023398705,"GHR, SUCLA2, SUCLG2, SUCLG1, SDHA, SDHB",3331,10,18082,3.257039928,1,0.474769219,0.465666394 GOTERM_BP_DIRECT,GO:0006098~pentose-phosphate shunt,6,0.161333692,0.023398705,"TPI1, G6PDX, TALDO1, PGLS, PGD, TKT",3331,10,18082,3.257039928,1,0.474769219,0.465666394 GOTERM_BP_DIRECT,GO:0032780~negative regulation of ATPase activity,6,0.161333692,0.023398705,"OXA1L, PXK, ATPIF1, PPIF, LTF, CNN3",3331,10,18082,3.257039928,1,0.474769219,0.465666394 GOTERM_BP_DIRECT,GO:0045931~positive regulation of mitotic cell cycle,12,0.322667384,0.023482426,"FOXA1, APP, POLDIP2, USP22, EIF4EBP1, CDK1, BIRC5, ASNS, PKN2, PRKCA, HMGB1, PAFAH1B1",3331,32,18082,2.035649955,1,0.474769219,0.465666394 GOTERM_BP_DIRECT,GO:0061077~chaperone-mediated protein folding,12,0.322667384,0.023482426,"FKBP1A, FKBP11, HSPA8, FKBP2, DNAJB6, CHORDC1, CANX, FKBP8, CALR, FKBP4, PPIB, PPID",3331,32,18082,2.035649955,1,0.474769219,0.465666394 GOTERM_BP_DIRECT,GO:0070555~response to interleukin-1,12,0.322667384,0.023482426,"IGBP1, GHR, GCLC, PRKCI, IRAK1, SRC, TAF9, CD38, CYBA, PRKCA, ETS1, AES",3331,32,18082,2.035649955,1,0.474769219,0.465666394 GOTERM_BP_DIRECT,GO:0032212~positive regulation of telomere maintenance via telomerase,12,0.322667384,0.023482426,"CCT6A, CCT3, CCT2, DKC1, TCP1, CTNNB1, MAPK1, CCT8, CCT7, CCT5, CCT4, MAPK3",3331,32,18082,2.035649955,1,0.474769219,0.465666394 GOTERM_BP_DIRECT,GO:0043388~positive regulation of DNA binding,12,0.322667384,0.023482426,"TXN1, TRIM28, MYC, HMGB2, EP300, HES1, CALM3, EDF1, CALM1, HIPK1, CALM2, NME1",3331,32,18082,2.035649955,1,0.474769219,0.465666394 GOTERM_BP_DIRECT,GO:0006487~protein N-linked glycosylation,13,0.349556332,0.023539337,"B4GALT1, RPN2, ALG6, ENTPD5, ALG5, PMM2, MOGS, DDOST, MGAT4A, MGAT4B, MGAT3, MGAT2, ST3GAL1",3331,36,18082,1.960255512,1,0.474769219,0.465666394 GOTERM_BP_DIRECT,GO:0070301~cellular response to hydrogen peroxide,18,0.484001076,0.024655636,"KDM6B, PLEKHA1, BNIP3, PRKCD, PARK7, KLF4, ETS1, AQP1, FABP1, CST3, NET1, TRPM2, AIFM1, RPS3, PPIF, CDK1, STAT6, NFE2L2",3331,57,18082,1.714231541,1,0.48711569,0.477776144 GOTERM_BP_DIRECT,GO:0006349~regulation of gene expression by genetic imprinting,8,0.215111589,0.024749472,"GSK3B, GSK3A, EED, KCNQ1OT1, KCNQ1, DNMT3A, CTCF, CTCFL",3331,17,18082,2.55454112,1,0.48711569,0.477776144 GOTERM_BP_DIRECT,GO:0060292~long term synaptic depression,8,0.215111589,0.024749472,"ARF1, STXBP1, PTEN, PICK1, PTK2B, CD38, ABHD6, MGLL",3331,17,18082,2.55454112,1,0.48711569,0.477776144 GOTERM_BP_DIRECT,GO:0043496~regulation of protein homodimerization activity,5,0.134444743,0.025027064,"ICA1, BAX, PCBD1, BAK1, TICAM1",3331,7,18082,3.877428486,1,0.48711569,0.477776144 GOTERM_BP_DIRECT,GO:0006526~arginine biosynthetic process,5,0.134444743,0.025027064,"CPS1, CAD, ASL, NAGS, OTC",3331,7,18082,3.877428486,1,0.48711569,0.477776144 GOTERM_BP_DIRECT,GO:0060396~growth hormone receptor signaling pathway,5,0.134444743,0.025027064,"GHR, SOCS2, STAT3, PXN, PIK3R1",3331,7,18082,3.877428486,1,0.48711569,0.477776144 GOTERM_BP_DIRECT,GO:0015825~L-serine transport,5,0.134444743,0.025027064,"SERINC1, SLC1A4, SLC1A5, SERINC3, SERINC2",3331,7,18082,3.877428486,1,0.48711569,0.477776144 GOTERM_BP_DIRECT,GO:0042760~very long-chain fatty acid catabolic process,5,0.134444743,0.025027064,"ACADVL, ABCD3, ACOT2, SLC27A2, SLC27A4",3331,7,18082,3.877428486,1,0.48711569,0.477776144 GOTERM_BP_DIRECT,GO:1903076~regulation of protein localization to plasma membrane,5,0.134444743,0.025027064,"VAMP8, STX8, STX7, SPTBN1, VTI1B",3331,7,18082,3.877428486,1,0.48711569,0.477776144 GOTERM_BP_DIRECT,GO:0038066~p38MAPK cascade,5,0.134444743,0.025027064,"ZFP36, MAPKAPK2, MAPK14, FGFR3, ZFP36L1",3331,7,18082,3.877428486,1,0.48711569,0.477776144 GOTERM_BP_DIRECT,GO:0055119~relaxation of cardiac muscle,5,0.134444743,0.025027064,"RGS2, P2RX4, ATP2A2, PDE5A, ATP1B1",3331,7,18082,3.877428486,1,0.48711569,0.477776144 GOTERM_BP_DIRECT,GO:0006729~tetrahydrobiopterin biosynthetic process,5,0.134444743,0.025027064,"QDPR, GCH1, SPR, PCBD1, PTS",3331,7,18082,3.877428486,1,0.48711569,0.477776144 GOTERM_BP_DIRECT,GO:0030838~positive regulation of actin filament polymerization,16,0.430223178,0.026750551,"ACTR3, VASP, MAP3K1, RHOA, PYCARD, BAIAP2L2, DLG1, ARPC2, CTTN, CDC42EP5, CDC42EP4, CDC42EP2, PTK2B, RAC1, PFN1, ARF6",3331,49,18082,1.772538736,1,0.519147329,0.509193635 GOTERM_BP_DIRECT,GO:0010628~positive regulation of gene expression,90,2.420005378,0.026933154,"GSK3B, DDX3X, CITED2, PDCD5, SERPINE1, PRKAG1, HMGB2, HNRNPU, CYP3A13, CTCF, PARK7, YY1, PPP3CA, HMGN5, TMED2, EP300, SOX9, LGALS9, REG1, KDM2A, ITGA3, PAX6, MYT1, TGFBR1, TNFRSF1A, HCFC1, OLFM1, PLSCR1, TMEM135, KIT, EZR, GAS6, ATF3, CD44, ATF4, PPP1R15A, NFAT5, KDM3A, DNMT1, ROCK2, SRC, NR1I2, PIK3R1, PHB, GATA3, HIF1A, DLL1, CDC42, PDCD10, LMNA, ERBB2, RPS3, AGR2, HES1, ZBTB7B, APOB, LDLR, WNT3, NKX2-2, EGR1, HSPA8, GSN, HSPA4, VDR, PTGES3, STAT3, RAB27A, PSG23, MAPK14, KLF4, NFKB1, VEGFA, CTCFL, RGCC, NAT8, TRP53, FUBP1, FEV, ID1, HNRNPD, CDK1, SPRY2, CTNNB1, KRAS, CALR, TCF3, VIM, OGT, RAB3GAP1, NFE2L2",3331,399,18082,1.224451101,1,0.521176044,0.511183454 GOTERM_BP_DIRECT,GO:0035264~multicellular organism growth,32,0.860446357,0.027112127,"PKDCC, ANKRD11, GIGYF2, ZFP36L1, CDC42, TNKS2, TMED2, RBBP6, WDTC1, SLC12A2, TCF7L2, KDM2A, G6PC, PLEKHA1, H3F3B, TAF10, H3F3A, ATRX, ARID5B, RC3H2, TARBP2, MFSD7B, NDUFS6, SELM, TRP53, GPD2, FKBP8, GNAS, DHCR7, RPL29, ATF5, LLGL2",3331,120,18082,1.447573301,1,0.523123013,0.513093093 GOTERM_BP_DIRECT,GO:0006879~cellular iron ion homeostasis,15,0.40333423,0.027698795,"EGLN1, TFRC, NCOA4, IREB2, SLC40A1, HIF1A, NUBP1, SOD1, FTL1, TTC7, HEPH, MYC, FTH1, ACO1, MON1A",3331,45,18082,1.809466627,1,0.532902468,0.522685045 GOTERM_BP_DIRECT,GO:0055088~lipid homeostasis,14,0.376445281,0.028523219,"CEBPA, ACADVL, G6PC, APOA4, ETFA, ACADSB, USF2, ACADL, ACOX1, HNF4A, ACADM, ACAD11, ACADS, PNPLA2",3331,41,18082,1.853599959,1,0.547186808,0.536695509 GOTERM_BP_DIRECT,GO:0030001~metal ion transport,10,0.268889486,0.028855411,"NDFIP2, SLC39A9, SLC39A11, SLC39A5, ATP1B3, SLC39A7, ATP1B1, SLC39A14, ATOX1, SLC39A4",3331,25,18082,2.171359952,1,0.551973427,0.541390353 GOTERM_BP_DIRECT,GO:0008643~carbohydrate transport,13,0.349556332,0.029159777,"SLC35A2, SLC35A1, SLC35A4, SLC37A1, SLC35B1, SLC35C1, SLC2A1, SLC2A2, SLC50A1, SLC5A1, SLC2A5, AKT1, SLC5A4B",3331,37,18082,1.907275633,1,0.556201927,0.545537779 GOTERM_BP_DIRECT,GO:0032008~positive regulation of TOR signaling,11,0.295778435,0.029477076,"FLCN, XBP1, GOLPH3, SEC13, RRAGD, LAMTOR2, LAMTOR1, LAMTOR4, GAS6, LAMTOR3, LAMTOR5",3331,29,18082,2.05904823,1,0.559059542,0.548340605 GOTERM_BP_DIRECT,GO:0006611~protein export from nucleus,11,0.295778435,0.029477076,"EIF5A, HSPA9, GSK3B, XPO1, AHCYL1, XPO6, CSE1L, CHP1, NUP88, CALR, RAN",3331,29,18082,2.05904823,1,0.559059542,0.548340605 GOTERM_BP_DIRECT,GO:0008610~lipid biosynthetic process,7,0.18822264,0.030239025,"DCTN6, ACLY, SREBF1, ACSS2, SCD1, PRPF19, FDFT1",3331,14,18082,2.71419994,1,0.559212547,0.548490677 GOTERM_BP_DIRECT,"GO:0030330~DNA damage response, signal transduction by p53 class mediator",7,0.18822264,0.030239025,"USP10, TRP53, MYO6, BCL3, ATRX, MIF, NDRG1",3331,14,18082,2.71419994,1,0.559212547,0.548490677 GOTERM_BP_DIRECT,GO:0070935~3'-UTR-mediated mRNA stabilization,7,0.18822264,0.030239025,"PTBP1, ZFP36, MAPKAPK2, HNRNPC, TARDBP, ELAVL1, HNRNPA0",3331,14,18082,2.71419994,1,0.559212547,0.548490677 GOTERM_BP_DIRECT,GO:0071850~mitotic cell cycle arrest,7,0.18822264,0.030239025,"GADD45GIP1, CDKN1A, CDKN1B, RGCC, DUSP1, GADD45A, TRP53",3331,14,18082,2.71419994,1,0.559212547,0.548490677 GOTERM_BP_DIRECT,GO:0046685~response to arsenic-containing substance,7,0.18822264,0.030239025,"ALAD, GCLC, CDKN1A, PTEN, CPOX, RNF4, NR3C1",3331,14,18082,2.71419994,1,0.559212547,0.548490677 GOTERM_BP_DIRECT,GO:1901653~cellular response to peptide,7,0.18822264,0.030239025,"KLF10, KLF5, ID1, AKT1, KLF4, KLF3, NFKB1",3331,14,18082,2.71419994,1,0.559212547,0.548490677 GOTERM_BP_DIRECT,GO:0045723~positive regulation of fatty acid biosynthetic process,7,0.18822264,0.030239025,"SREBF1, MLXIPL, HNF4A, APOC2, MID1IP1, APOA1, APOA4",3331,14,18082,2.71419994,1,0.559212547,0.548490677 GOTERM_BP_DIRECT,GO:0006044~N-acetylglucosamine metabolic process,7,0.18822264,0.030239025,"MGEA5, GNPDA2, AMDHD2, HEXB, MGAT3, CHST4, CHST2",3331,14,18082,2.71419994,1,0.559212547,0.548490677 GOTERM_BP_DIRECT,GO:0006107~oxaloacetate metabolic process,7,0.18822264,0.030239025,"GHR, CS, ACLY, MDH1, MDH2, GOT2, PCK2",3331,14,18082,2.71419994,1,0.559212547,0.548490677 GOTERM_BP_DIRECT,GO:0019882~antigen processing and presentation,17,0.457112127,0.030489784,"RAB3B, CD74, RAB3C, RAB4A, H2-EB1, H2-K1, AP3D1, RAB27A, AP3B1, H2-AA, H2-Q1, PSMB8, RAB10, GM11127, RAB6A, H2-D1, H2-AB1",3331,54,18082,1.708940703,1,0.562292257,0.551511339 GOTERM_BP_DIRECT,GO:0000209~protein polyubiquitination,28,0.752890562,0.031348991,"CBFB, CUL3, UBE2D3, PRPF19, UBE2D2A, UBE2L3, RNF114, TNKS2, HLTF, RNF20, ANKIB1, UBE2B, UBE2C, FBXW11, AMFR, UBE4B, MARCH5, RC3H2, RNF145, UBE2W, RNF167, CDC34, UBE2S, PELI1, RNF181, RBCK1, UBE2K, TAF1",3331,103,18082,1.475681521,1,0.576545076,0.565490886 GOTERM_BP_DIRECT,GO:0006606~protein import into nucleus,19,0.510890024,0.032254301,"RANBP1, HSPA8, CSE1L, STAT3, PTTG1IP, PPP3CA, NUP85, NUP50, NUP62, CFL1, TPR, KPNA6, TXNIP, PHIP, NUP88, KPNA2, TNPO2, KPNB1, RAN",3331,63,18082,1.637136472,1,0.591565144,0.580222972 GOTERM_BP_DIRECT,GO:0035019~somatic stem cell population maintenance,15,0.40333423,0.033268773,"KLF10, TCF7L2, CDX2, LDB1, ERDR1, PLA2G2A, ASCL2, ZFP36L2, APC, KIT, PRDM16, HES1, SOX9, FGFR3, SOX4",3331,46,18082,1.770130396,1,0.606836968,0.595201987 GOTERM_BP_DIRECT,GO:0010506~regulation of autophagy,15,0.40333423,0.033268773,"XBP1, USP10, USP33, CISD2, HMGB1, VMP1, PYCARD, NLRP6, RRAGD, CASP1, ABL2, CHMP4B, ULK1, PIP4K2C, BOK",3331,46,18082,1.770130396,1,0.606836968,0.595201987 GOTERM_BP_DIRECT,GO:0010629~negative regulation of gene expression,62,1.667114816,0.033501472,"CDKN1A, CITED2, EIF4A3, SERPINE1, HMGB2, INPPL1, KEAP1, CTCF, PARK7, YY1, FLCN, PPP3CA, MYC, AKT1, SOX9, LGALS9, TGIF1, MAP2K2, KDM2A, SLC35C2, CNPY2, MIF, MYT1, POU3F2, TNFRSF1A, NME1, AES, OLFM1, NCOR1, MYADM, PICK1, ADNP, SRSF6, ZFP148, TMF1, HDAC1, GATA3, CDC42, RXRA, PDCD10, HES1, BAK1, GAS2L1, XDH, LDLR, NPM1, NDFIP2, HSPA4, WWP2, KLF4, NFKB1, VEGFA, HNRNPK, TRP53, ID1, HNRNPD, ID3, CTNNB1, TARDBP, FGFR3, PICALM, TAF1",3331,265,18082,1.270040727,1,0.609416415,0.597731978 GOTERM_BP_DIRECT,GO:0046827~positive regulation of protein export from nucleus,8,0.215111589,0.034210304,"PPM1A, TCF7L2, GSK3B, RANBP3, TPR, ANP32B, GAS6, PRKACA",3331,18,18082,2.412622169,1,0.613946205,0.602174918 GOTERM_BP_DIRECT,GO:2000573~positive regulation of DNA biosynthetic process,8,0.215111589,0.034210304,"GSK3B, RGCC, DDX39B, SRC, MYC, PTK2B, PAK3, GFER",3331,18,18082,2.412622169,1,0.613946205,0.602174918 GOTERM_BP_DIRECT,GO:0022408~negative regulation of cell-cell adhesion,8,0.215111589,0.034210304,"CDH1, ABL2, PIK3R1, SPINT2, B4GALNT2, MUC4, GTPBP4, VEGFA",3331,18,18082,2.412622169,1,0.613946205,0.602174918 GOTERM_BP_DIRECT,GO:0051693~actin filament capping,8,0.215111589,0.034210304,"VIL1, GSN, CAPZB, CAPZA1, TPM1, CAPZA2, MYH9, SPTBN1",3331,18,18082,2.412622169,1,0.613946205,0.602174918 GOTERM_BP_DIRECT,GO:0010613~positive regulation of cardiac muscle hypertrophy,8,0.215111589,0.034210304,"CDK9, MTPN, PPP3CA, PARP1, ADK, PDE5A, ECE1, PRKCA",3331,18,18082,2.412622169,1,0.613946205,0.602174918 GOTERM_BP_DIRECT,GO:0008285~negative regulation of cell proliferation,86,2.312449583,0.035504359,"DDR1, ITGB1, IFITM3, CDKN1A, BTG2, B4GALT1, CDKN1B, BTG1, SMARCB1, TES, PDCD5, PTEN, INPPL1, CIB1, PTPRK, PTPRF, FGFRL1, HNF4A, FTH1, NUP62, HIST1H2AE, WDR6, PIM2, SOX9, REG1, JARID2, ARID2, SOX4, TGIF1, HIST1H2AO, PBRM1, KLF13, PRKCA, PAX6, PPP2R5C, AXIN2, SSTR1, CBFA2T3, GTPBP4, ASPH, IRF1, IRF6, ATF5, CEBPA, TSG101, HDAC1, PHB, GATA3, TOB1, NDRG1, DLL1, TBRG1, SLC9A3R1, MUC2, RXRA, CLMN, TMEM127, SMYD2, PTK2B, CSK, BAK1, BCHE, JUN, NPM1, ERDR1, VDR, PLA2G2A, STAT3, DHCR24, SOD2, KLF4, SMARCA2, CHERP, RGCC, APC, NFIB, TRP53, CTH, DNAJA3, SPRY2, CTNNB1, CD9, BAX, INSM1, FGFR3, FOXA3",3331,384,18082,1.21573539,1,0.632308622,0.62018527 GOTERM_BP_DIRECT,GO:0072593~reactive oxygen species metabolic process,13,0.349556332,0.035687417,"NDUFA13, BNIP3, MPV17L, ATPIF1, CYBA, SOD1, PRDX4, SH3PXD2A, RFK, NDUFS4, DDIT4, NDUFS3, NDUFS1",3331,38,18082,1.857084169,1,0.632308622,0.62018527 GOTERM_BP_DIRECT,GO:0030335~positive regulation of cell migration,49,1.317558483,0.035698388,"ITGB1, PRR5, ONECUT2, CIB1, HMGB1, FGF1, ETS1, CX3CL1, IGF1R, CCAR1, AQP1, MYLK, PLAU, PRKCA, ACTN4, ADRA2A, TGFBR1, RHOA, KIT, MYADM, HBEGF, GRB7, ZFP703, PDGFA, FURIN, PIK3R1, PLD1, THBS1, EGFR, FAM83H, SDCBP, PAK1, MIEN1, PDCD10, PTK2B, MAPK1, SEMA4A, XBP1, HSPA5, SEMA4B, ELP3, SEMA4G, SSH2, VEGFA, VIL1, APC, SELK, INSM1, BCAR1",3331,203,18082,1.310303419,1,0.632308622,0.62018527 GOTERM_BP_DIRECT,GO:0006626~protein targeting to mitochondrion,9,0.242000538,0.036287814,"FIS1, TOMM40, MTX1, DUSP18, MFF, TOMM20, YWHAZ, TIMM8A1, TOMM5",3331,22,18082,2.220709042,1,0.632308622,0.62018527 GOTERM_BP_DIRECT,GO:0016486~peptide hormone processing,6,0.161333692,0.036502877,"PCSK1, PCSK1N, SCG5, FURIN, ECE1, PCSK5",3331,11,18082,2.960945389,1,0.632308622,0.62018527 GOTERM_BP_DIRECT,GO:0051639~actin filament network formation,6,0.161333692,0.036502877,"ACTN1, COBL, ARPC5, LCP1, ESPN, PLS1",3331,11,18082,2.960945389,1,0.632308622,0.62018527 GOTERM_BP_DIRECT,GO:2000637~positive regulation of gene silencing by miRNA,6,0.161333692,0.036502877,"ZFP36, STAT3, PUM1, LIMD1, NFKB1, PUM2",3331,11,18082,2.960945389,1,0.632308622,0.62018527 GOTERM_BP_DIRECT,GO:0034067~protein localization to Golgi apparatus,6,0.161333692,0.036502877,"IFT20, ATG9A, GBF1, GCC2, CSNK1D, RAB6A",3331,11,18082,2.960945389,1,0.632308622,0.62018527 GOTERM_BP_DIRECT,GO:0030277~maintenance of gastrointestinal epithelium,6,0.161333692,0.036502877,"PBLD1, RBP4, MUC2, STRAP, MUC13, PBLD2",3331,11,18082,2.960945389,1,0.632308622,0.62018527 GOTERM_BP_DIRECT,GO:0045647~negative regulation of erythrocyte differentiation,6,0.161333692,0.036502877,"HSPA9, ZFP36, KLF13, LDB1, GAS2L1, ZFP36L1",3331,11,18082,2.960945389,1,0.632308622,0.62018527 GOTERM_BP_DIRECT,GO:0019953~sexual reproduction,6,0.161333692,0.036502877,"HEXB, STAT3, HEXA, EIF4H, AFP, SEPP1",3331,11,18082,2.960945389,1,0.632308622,0.62018527 GOTERM_BP_DIRECT,GO:0000050~urea cycle,6,0.161333692,0.036502877,"CEBPA, CPS1, CAD, ASL, NAGS, OTC",3331,11,18082,2.960945389,1,0.632308622,0.62018527 GOTERM_BP_DIRECT,GO:0000422~mitophagy,12,0.322667384,0.03658837,"ATG3, FIS1, GABARAPL2, FUNDC2, MAP1LC3B, GABARAPL1, RB1CC1, ATG9A, ATG2A, CISD2, GABARAP, ATG5",3331,34,18082,1.91590584,1,0.632308622,0.62018527 GOTERM_BP_DIRECT,GO:0072661~protein targeting to plasma membrane,10,0.268889486,0.037119923,"NFASC, ANXA2, BSG, MYADM, PRKG2, TMED2, ATP2C2, GAS6, MYL12A, SPTBN1",3331,26,18082,2.087846108,1,0.632308622,0.62018527 GOTERM_BP_DIRECT,GO:0006829~zinc II ion transport,10,0.268889486,0.037119923,"SLC30A7, SLC39A9, AP3D1, SLC39A11, SLC39A5, AP3B1, SLC39A7, SLC30A10, SLC39A14, SLC39A4",3331,26,18082,2.087846108,1,0.632308622,0.62018527 GOTERM_BP_DIRECT,GO:0043488~regulation of mRNA stability,10,0.268889486,0.037119923,"ZFP36, RNASEL, PABPC4, KHSRP, HNRNPD, MAPK14, PUM1, ZFP36L2, ZFP36L1, PUM2",3331,26,18082,2.087846108,1,0.632308622,0.62018527 GOTERM_BP_DIRECT,GO:1903146~regulation of mitophagy,10,0.268889486,0.037119923,"BNIP3L, SREBF1, MAP1LC3B, GSK3A, CTTN, U2AF2, VDAC1, WBP11, RPL28, SREBF2",3331,26,18082,2.087846108,1,0.632308622,0.62018527 GOTERM_BP_DIRECT,GO:0050790~regulation of catalytic activity,10,0.268889486,0.037119923,"FXYD3, FDX1, PRKAG1, PRKAG2, AUP1, SOD2, APBA3, TRIB1, HIF1A, CTSB",3331,26,18082,2.087846108,1,0.632308622,0.62018527 GOTERM_BP_DIRECT,GO:0090200~positive regulation of release of cytochrome c from mitochondria,11,0.295778435,0.037127768,"PYCARD, FAM162A, BAD, BNIP3, TRP53, PDCD5, PPIF, BAX, APOPT1, BAK1, MFF",3331,30,18082,1.990413289,1,0.632308622,0.62018527 GOTERM_BP_DIRECT,GO:0032570~response to progesterone,11,0.295778435,0.037127768,"GPI1, SREBF1, CLDN4, BAD, TSPO, TXNIP, FOSB, CD38, DSG2, FOS, NKX2-2",3331,30,18082,1.990413289,1,0.632308622,0.62018527 GOTERM_BP_DIRECT,GO:0018105~peptidyl-serine phosphorylation,34,0.914224254,0.039734094,"CAMK2B, GSK3B, SMG1, CAB39, MAST3, SRC, MAST2, PRKCZ, MKNK2, STK38, PBK, AKT1, PDK3, MAPK1, PRKACA, PAK2, PDK2, MAPK3, PRKCI, CSNK1A1, PRKCD, PLK1, PRKCA, CSNK1D, MAPK14, TGFBR1, MAPK13, CLK1, MAPKAPK2, CDK1, PKN2, ULK1, GAS6, TAF1",3331,133,18082,1.387711247,1,0.674974071,0.662032687 GOTERM_BP_DIRECT,GO:0031100~organ regeneration,17,0.457112127,0.041917429,"CDKN1A, GSTP1, CAD, APOA1, PHB, MKI67, IGF2R, CCNA2, ATIC, PKM, CCND1, CDK4, PPAT, CDK1, LCP1, BAK1, GAS6",3331,56,18082,1.647907106,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0050829~defense response to Gram-negative bacterium,17,0.457112127,0.041917429,"CHGA, REG3B, GSDMD, APP, MMP7, DEFA6, TUSC2, SERPINE1, LYZ1, HMGB2, DEFA3, LYPD8, PYCARD, NAIP5, DEFA17, B2M, OPTN",3331,56,18082,1.647907106,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0032355~response to estradiol,27,0.726001613,0.041955993,"FOXA1, GRN, CDKN1B, GSTP1, PTEN, ETS1, CST3, GPI1, SOCS2, CCND1, MYC, CD38, ESRRA, MBD3, NQO1, BAD, DUSP1, MBD2, STAT3, DNMT3A, PRKCA, EEF2, CAT, TXNIP, CTNNB1, CALR, PAM",3331,101,18082,1.451156404,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0043968~histone H2A acetylation,7,0.18822264,0.042729985,"MORF4L1, MORF4L2, RUVBL2, EP400, EPC1, YEATS4, BRD8",3331,15,18082,2.533253277,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0046039~GTP metabolic process,5,0.134444743,0.042850443,"GNAI3, AK3, AK4, AMPD2, RHOA",3331,8,18082,3.392749925,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0043486~histone exchange,5,0.134444743,0.042850443,"ZNHIT1, NASP, ANP32E, ANP32B, PTMA",3331,8,18082,3.392749925,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:1903428~positive regulation of reactive oxygen species biosynthetic process,5,0.134444743,0.042850443,"RAB27A, CYBA, PARK7, CLCN3, OGT",3331,8,18082,3.392749925,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0032471~negative regulation of endoplasmic reticulum calcium ion concentration,5,0.134444743,0.042850443,"BCAP31, FIS1, BAX, BAK1, TGM2",3331,8,18082,3.392749925,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0006101~citrate metabolic process,5,0.134444743,0.042850443,"GHR, CS, ACLY, ACO1, ACO2",3331,8,18082,3.392749925,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0048102~autophagic cell death,5,0.134444743,0.042850443,"SH3GLB1, CDKN1B, LAMP1, CTSL, BNIP3",3331,8,18082,3.392749925,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0016458~gene silencing,5,0.134444743,0.042850443,"DNMT1, ATF6B, KCNQ1OT1, KCNQ1, CHMP1A",3331,8,18082,3.392749925,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0030858~positive regulation of epithelial cell differentiation,5,0.134444743,0.042850443,"DMBT1, APC, CTNNB1, PAX6, SOX9",3331,8,18082,3.392749925,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0034498~early endosome to Golgi transport,5,0.134444743,0.042850443,"SNX1, SNX2, TRAPPC10, STX5A, RAB6A",3331,8,18082,3.392749925,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0051014~actin filament severing,5,0.134444743,0.042850443,"VIL1, DBNL, GSN, FLII, DSTN",3331,8,18082,3.392749925,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0060316~positive regulation of ryanodine-sensitive calcium-release channel activity,5,0.134444743,0.042850443,"GSTO1, CALM3, CALM1, GSTM7, CALM2",3331,8,18082,3.392749925,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:2000145~regulation of cell motility,5,0.134444743,0.042850443,"IGSF8, CD81, ARHGAP18, PKN2, SSX2IP",3331,8,18082,3.392749925,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0032436~positive regulation of proteasomal ubiquitin-dependent protein catabolic process,19,0.510890024,0.043106548,"GSK3B, VCP, ANKIB1, CSNK1A1, PLK1, CSNK1D, PSEN1, RCHY1, CBFA2T3, GCLC, RNF114, SUMO1, RFWD2, DVL1, SUMO2, UBE2V2, AKT1, TRIB1, TAF1",3331,65,18082,1.586763042,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0045595~regulation of cell differentiation,13,0.349556332,0.043185115,"PLEKHB2, PLEKHB1, HMGB2, KLF4, POU3F2, PTBP3, EID1, APC, STK24, SPRY2, CTNNB1, SOX9, NKX2-2",3331,39,18082,1.809466627,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0033077~T cell differentiation in thymus,13,0.349556332,0.043185115,"NCAPH2, RPS6, RORC, GATA3, ZFP36L2, ZFP36L1, JMJD6, APC, DNAJA3, TRP53, CTNNB1, TCF3, B2M",3331,39,18082,1.809466627,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0006641~triglyceride metabolic process,13,0.349556332,0.043185115,"CPT1A, G6PC, GPX1, INSIG1, MTTP, SEL1L, ACSL6, APOC3, PCSK9, DBI, CAT, SCD1, SLC37A4",3331,39,18082,1.809466627,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0009060~aerobic respiration,13,0.349556332,0.043185115,"ADSL, UQCRB, UQCR10, COX6A1, SDHB, OXA1L, BLOC1S1, CAT, UQCRC1, PMPCB, UQCRC2, NDUFV1, COX20",3331,39,18082,1.809466627,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0006633~fatty acid biosynthetic process,21,0.564667921,0.043505908,"ELOVL1, ABCD3, MECR, PTGES2, PTGES3, TECR, PRKAG1, PRKAG2, H2-KE6, ACSL3, ACLY, FAM213B, FASN, NDUFAB1, PCCB, SCD2, SC5D, DEGS1, SCD1, MGLL, FADS1",3331,74,18082,1.540491858,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0051865~protein autoubiquitination,16,0.430223178,0.044305016,"RNF10, UBE2B, UHRF1, AMFR, UBE2D3, WWP2, UBE4B, RCHY1, UBE2D2A, RNF4, MARCH5, CNOT4, HECTD1, RNF181, RNF187, RNF220",3331,52,18082,1.670276886,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0010043~response to zinc ion,12,0.322667384,0.044761106,"ALAD, SLC30A7, DDX19B, CPS1, GSTA4, PTEN, ALDOB, SOD2, SLC30A10, CRIP1, OTC, KHK",3331,35,18082,1.861165673,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0031667~response to nutrient levels,12,0.322667384,0.044761106,"CST3, MBD3, MMP7, SRC, GSS, GSTP1, MBD2, SORD, CYBA, REG1, SOD2, SOD1",3331,35,18082,1.861165673,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0000470~maturation of LSU-rRNA,8,0.215111589,0.045790971,"RSL1D1, RPL7A, NSA2, MRPL1, EIF6, NHP2L1, NHP2, RPL10A",3331,19,18082,2.285642055,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0000245~spliceosomal complex assembly,8,0.215111589,0.045790971,"DDX39B, SCAF11, SNRPD1, SNRPD3, PRPF19, TXNL4A, SF3B1, LSM4",3331,19,18082,2.285642055,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0031334~positive regulation of protein complex assembly,8,0.215111589,0.045790971,"GSK3B, VCP, SUMO1, FAF1, PIH1D1, PPP2R5B, FNIP1, VEGFA",3331,19,18082,2.285642055,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0030278~regulation of ossification,8,0.215111589,0.045790971,"ESRRA, CREB3L1, MAPK1, MAPK14, FGFR3, PBX1, DHRS3, MAPK3",3331,19,18082,2.285642055,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0006730~one-carbon metabolic process,11,0.295778435,0.046047239,"AHCYL2, AHCY, AHCYL1, MAT2A, MTHFD1, SHMT2, MTHFD2, SHMT1, CAR9, MAT2B, CAR8",3331,31,18082,1.926206409,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0044027~hypermethylation of CpG island,4,0.107555795,0.046452372,"GSK3B, GSK3A, KCNQ1OT1, DNMT3A",3331,5,18082,4.342719904,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0036035~osteoclast development,4,0.107555795,0.046452372,"ANXA2, SRC, PAFAH1B1, FOXP1",3331,5,18082,4.342719904,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0070389~chaperone cofactor-dependent protein refolding,4,0.107555795,0.046452372,"DNAJC7, ST13, PTGES3, BAG1",3331,5,18082,4.342719904,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0015760~glucose-6-phosphate transport,4,0.107555795,0.046452372,"G6PC3, SLC37A1, G6PC, SLC37A4",3331,5,18082,4.342719904,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0071569~protein ufmylation,4,0.107555795,0.046452372,"UFM1, UBA5, UFC1, CDK5RAP3",3331,5,18082,4.342719904,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0031325~positive regulation of cellular metabolic process,4,0.107555795,0.046452372,"MLXIPL, PKLR, MLX, EP300",3331,5,18082,4.342719904,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:1903071~positive regulation of ER-associated ubiquitin-dependent protein catabolic process,4,0.107555795,0.046452372,"BCAP31, SGTA, UBQLN1, HERPUD1",3331,5,18082,4.342719904,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0061615~glycolytic process through fructose-6-phosphate,4,0.107555795,0.046452372,"PFKL, ALDOB, ALDOA, PFKP",3331,5,18082,4.342719904,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0052548~regulation of endopeptidase activity,4,0.107555795,0.046452372,"PSMA3, NRD1, FURIN, PSMB8",3331,5,18082,4.342719904,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0006089~lactate metabolic process,4,0.107555795,0.046452372,"PFKFB2, MTCH2, SLC37A4, HIF1A",3331,5,18082,4.342719904,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0006085~acetyl-CoA biosynthetic process,4,0.107555795,0.046452372,"ACLY, ACSS2, ACSS1, ACAT1",3331,5,18082,4.342719904,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0002904~positive regulation of B cell apoptotic process,4,0.107555795,0.046452372,"CD24A, MYC, BAX, FNIP1",3331,5,18082,4.342719904,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0090324~negative regulation of oxidative phosphorylation,4,0.107555795,0.046452372,"MLXIPL, PPIF, APOC3, RHOA",3331,5,18082,4.342719904,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0003310~pancreatic A cell differentiation,4,0.107555795,0.046452372,"RFX6, GATA6, PAX6, INSM1",3331,5,18082,4.342719904,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:1990182~exosomal secretion,4,0.107555795,0.046452372,"COPS5, TSG101, RAB27A, RAB11A",3331,5,18082,4.342719904,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0070934~CRD-mediated mRNA stabilization,4,0.107555795,0.046452372,"SYNCRIP, DHX9, HNRNPU, YBX1",3331,5,18082,4.342719904,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0071681~cellular response to indole-3-methanol,4,0.107555795,0.046452372,"JUP, CDH1, CTNNA1, CTNNB1",3331,5,18082,4.342719904,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0034435~cholesterol esterification,4,0.107555795,0.046452372,"STARD4, SOAT1, SOAT2, SCD1",3331,5,18082,4.342719904,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0014074~response to purine-containing compound,4,0.107555795,0.046452372,"TRPM2, HMGCS1, ADSS, AACS",3331,5,18082,4.342719904,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0055129~L-proline biosynthetic process,4,0.107555795,0.046452372,"OAT, PYCRL, PYCR2, ALDH18A1",3331,5,18082,4.342719904,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:1900103~positive regulation of endoplasmic reticulum unfolded protein response,4,0.107555795,0.046452372,"XBP1, BAX, BAK1, PIK3R1",3331,5,18082,4.342719904,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0043280~positive regulation of cysteine-type endopeptidase activity involved in apoptotic process,15,0.40333423,0.046754512,"BCAP31, FIS1, MTCH2, NDUFA13, DDX3X, BAD, PDCD6, PDCD5, ARRB1, UACA, RHOA, PYCARD, PPP2CA, MYC, APOPT1",3331,48,18082,1.696374962,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0070830~bicellular tight junction assembly,10,0.268889486,0.046861889,"ITGB1, OCLN, DLG1, CLDN3, CDH1, PARD3, MICALL2, CGN, ACTN4, MPP5",3331,27,18082,2.010518474,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0007029~endoplasmic reticulum organization,10,0.268889486,0.046861889,"VMP1, LMAN1, SEC61A1, JAGN1, SEC16A, LMAN2, PEX5, TOR1AIP2, TOR1B, USE1",3331,27,18082,2.010518474,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0034198~cellular response to amino acid starvation,10,0.268889486,0.046861889,"SH3GLB1, HNRNPL, DAP, CDKN1A, UCP2, ULK1, SLC38A2, EIF2S1, ATF3, ATF4",3331,27,18082,2.010518474,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:1900182~positive regulation of protein localization to nucleus,9,0.242000538,0.046924777,"TRIM8, HNRNPM, PARP1, SRC, CDK1, AKT1, PARK7, OGT, CDK5RAP3",3331,23,18082,2.124156475,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0002026~regulation of the force of heart contraction,9,0.242000538,0.046924777,"CHGA, GLRX3, GAA, ATP2A2, PEBP1, PDE5A, PRKCA, ATP1A1, SLC8A1",3331,23,18082,2.124156475,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0006491~N-glycan processing,9,0.242000538,0.046924777,"MAN1A, FUT8, PRKCSH, MAN2A1, EDEM1, MGAT4A, EDEM2, MGAT4B, ENGASE",3331,23,18082,2.124156475,1,0.694611549,0.681293652 GOTERM_BP_DIRECT,GO:0046777~protein autophosphorylation,44,1.18311374,0.048977109,"DDR1, CAMK2B, GSK3B, SMG1, SRC, EGFR, IGF1R, PAK1, SLK, TRIM28, IRAK1, MKNK2, STK16, ERBB2, PIM3, CSK, PIM2, PRKACA, PAK2, EPHB4, MARK2, JAK1, EPHB3, HSPA8, PRKCD, CAD, MINK1, NME2, PRKCA, MAPK14, EIF2S1, TGFBR1, CLK2, CLK1, TAOK3, STK24, WNK1, STK17B, MAPKAPK2, KIT, ULK1, FGFR3, MAP3K11, TAF1",3331,183,18082,1.305189042,1,0.723387561,0.709517937 GOTERM_BP_DIRECT,GO:2001237~negative regulation of extrinsic apoptotic signaling pathway,14,0.376445281,0.049237014,"TCF7L2, SRC, GSTP1, PARK7, TGFBR1, VEGFA, PRDX2, GCLC, CTTN, RB1CC1, LMNA, PHIP, GCLM, ZMYND11",3331,44,18082,1.727218144,1,0.723527681,0.709655371 GOTERM_BP_DIRECT,GO:0071407~cellular response to organic cyclic compound,21,0.564667921,0.049409502,"GSTM3, CEBPA, GSK3A, CDKN1B, HSP90AB1, TMF1, MBD2, STAT3, CYBA, AXIN2, SMAD5, NFKB1, HCFC1, RAP1B, PAK1, KLF5, RAP1A, ARHGDIA, AKT1, PAK3, PAK2",3331,75,18082,1.519951966,1,0.723527681,0.709655371 GOTERM_BP_DIRECT,GO:0070373~negative regulation of ERK1 and ERK2 cascade,19,0.510890024,0.049420105,"DUSP1, GSTP1, PTEN, FBLN1, ARRB1, PHB, SYNJ2BP, KLF4, FLCN, ACE2, SLC9A3R1, DLG1, NLRP6, SPRY2, PIN1, CSK, EZR, EIF3A, ATF3",3331,66,18082,1.562721178,1,0.723527681,0.709655371 GOTERM_BP_DIRECT,GO:0032088~negative regulation of NF-kappaB transcription factor activity,19,0.510890024,0.049420105,"ZCCHC11, USP7, ANXA4, ARRB1, COMMD1, KLF4, COMMD6, COMMD7, PYCARD, PRDX2, DAP, IRAK1, DNAJA3, CAT, PELI1, TAX1BP1, CHP1, RBCK1, CDK5RAP3",3331,66,18082,1.562721178,1,0.723527681,0.709655371 GOTERM_BP_DIRECT,GO:1903955~positive regulation of protein targeting to mitochondrion,22,0.59155687,0.052237112,"SH3GLB1, GSK3A, STARD7, UBE2D3, EPT1, HPS4, WBP11, SREBF2, UBE2L3, PSMD8, UBL5, PSMB7, CYB5R1, NPEPPS, U2AF2, FAM20B, MICALL2, TOMM7, HES1, RHOU, SAE1, RPL28",3331,80,18082,1.492809967,1,0.760411282,0.745831796 GOTERM_BP_DIRECT,GO:0000082~G1/S transition of mitotic cell cycle,18,0.484001076,0.052665845,"CAMK2B, ITGB1, RANBP1, CDKN1A, CDKN1B, TAF10, RPS6, PPP3CA, RGCC, CCND2, CCND1, CDK4, PPAT, MYB, EIF4EBP1, RHOU, ANP32B, PIM2",3331,62,18082,1.575987062,1,0.760411282,0.745831796 GOTERM_BP_DIRECT,GO:0006360~transcription from RNA polymerase I promoter,6,0.161333692,0.053306243,"CEBPA, POLR2E, POLR2F, POLR2H, POLR2K, POLR2L",3331,12,18082,2.71419994,1,0.760411282,0.745831796 GOTERM_BP_DIRECT,GO:1902894~negative regulation of pri-miRNA transcription from RNA polymerase II promoter,6,0.161333692,0.053306243,"YY1, NFIB, GATA6, NFATC3, SOX9, PPARA",3331,12,18082,2.71419994,1,0.760411282,0.745831796 GOTERM_BP_DIRECT,GO:0045717~negative regulation of fatty acid biosynthetic process,6,0.161333692,0.053306243,"ACADVL, CEACAM1, ACADL, INSIG1, APOC3, WDTC1",3331,12,18082,2.71419994,1,0.760411282,0.745831796 GOTERM_BP_DIRECT,GO:0071712~ER-associated misfolded protein catabolic process,6,0.161333692,0.053306243,"UFD1L, VCP, SDF2L1, DERL1, RNF5, UGGT1",3331,12,18082,2.71419994,1,0.760411282,0.745831796 GOTERM_BP_DIRECT,GO:0006851~mitochondrial calcium ion transport,6,0.161333692,0.053306243,"STOML2, SMDT1, MCUR1, VDAC1, MICU2, BHLHA15",3331,12,18082,2.71419994,1,0.760411282,0.745831796 GOTERM_BP_DIRECT,GO:0051223~regulation of protein transport,6,0.161333692,0.053306243,"DNAJA1, SCFD1, SELK, RAB8A, RAB11A, PICALM",3331,12,18082,2.71419994,1,0.760411282,0.745831796 GOTERM_BP_DIRECT,GO:0033327~Leydig cell differentiation,6,0.161333692,0.053306243,"TMF1, PLEKHA1, CCND1, MAP7, MGST1, SF1",3331,12,18082,2.71419994,1,0.760411282,0.745831796 GOTERM_BP_DIRECT,GO:0045722~positive regulation of gluconeogenesis,6,0.161333692,0.053306243,"TCF7L2, DGAT2, HNF4A, PPARA, HIF1A, ARPP19",3331,12,18082,2.71419994,1,0.760411282,0.745831796 GOTERM_BP_DIRECT,GO:0010614~negative regulation of cardiac muscle hypertrophy,6,0.161333692,0.053306243,"GSK3B, RGS2, P2RX4, GLRX3, FBXO32, JARID2",3331,12,18082,2.71419994,1,0.760411282,0.745831796 GOTERM_BP_DIRECT,GO:0006995~cellular response to nitrogen starvation,6,0.161333692,0.053306243,"GABARAPL2, MAP1LC3B, GABARAPL1, RB1CC1, GABARAP, ATG5",3331,12,18082,2.71419994,1,0.760411282,0.745831796 GOTERM_BP_DIRECT,GO:0006665~sphingolipid metabolic process,12,0.322667384,0.054098684,"SMPD3, SMPD2, SPTLC1, GAL3ST1, ASAH2, SPTLC2, PSAP, SERINC1, SPTSSA, SGMS2, SERINC3, SERINC2",3331,36,18082,1.809466627,1,0.770069969,0.755305296 GOTERM_BP_DIRECT,"GO:0045892~negative regulation of transcription, DNA-templated",123,3.307340683,0.054597972,"NDUFA13, KDM1A, GMNN, EHMT1, RORB, PHB2, DACH1, TRIM28, MYB, EPC1, CIR1, SOX9, TLE2, SMARCC2, FBXW11, FOXP1, ERN2, EID1, ILF3, ATF5, ATF3, KHDRBS1, DNMT1, SET, TSG101, CTBP2, MAGED1, CTBP1, GATA6, GATA3, PHB, ZBTB4, IRAK1, DEAF1, NACC1, PRDM16, ZBTB7A, SNX6, FZD1, HEXIM1, HSPA8, JUN, CBX5, UBE2I, VDR, CBX3, ATP8B1, NONO, PHF12, PA2G4, SMARCA2, NFKB1, MLXIPL, GCLC, DAP, SNW1, TRP53, BCL3, ID1, BHLHE40, ID3, CALR, CDKN1B, THRA, LDB1, CITED2, YWHAB, CHD8, BHLHE41, FHL2, HMGB2, PTPRK, CTCF, LIMD1, FLCN, NIPBL, YWHAQ, SUMO1, SIN3B, CHMP1A, SUMO2, MLX, CD38, NELFB, JARID2, KLF10, RFC1, CBFA2T3, COMMD7, AES, SFPQ, NCOR1, ELF3, IRF1, BIRC5, GAS6, PFDN5, CEBPA, ZFP148, ATF6B, ZFP703, SRC, HDAC1, NR1I3, NR1I2, PURB, BCLAF1, DNAJB6, HES1, RBBP7, RUNX1T1, SMARCE1, TCF7L2, PCGF6, WWP2, KLF4, GATAD2A, PSMC5, MYBBP1A, NFIC, PDCD4, CTNNB1, LGR4",3331,579,18082,1.153183394,1,0.775523529,0.760654294 GOTERM_BP_DIRECT,GO:0098779~mitophagy in response to mitochondrial depolarization,33,0.887335305,0.056109246,"NDUFB9, REP15, SLC1A4, KRCC1, LARP1B, HK2, MYLK, BLOC1S1, SNRPD1, SLC37A4, COX8A, FGFBP1, YIPF1, MDH1, ATPIF1, SLC35C1, ANXA5, NME2, ATP1B1, LSM4, EIF2S1, FABP1, 1810022K09RIK, CDC37, MAP1A, TOMM7, ACIN1, ULK1, SNRPF, SQSTM1, PFKP, PI4K2A, SNRPB",3331,132,18082,1.35709997,1,0.79369491,0.778477272 GOTERM_BP_DIRECT,GO:0050885~neuromuscular process controlling balance,17,0.457112127,0.056115039,"CAMK2B, APP, CLIC5, HEXB, GAA, APLP2, EI24, HEXA, USH1C, CACNA1A, GIGYF2, ABR, CLN3, CAMTA1, ABL2, TPP1, PAFAH1B1",3331,58,18082,1.591082723,1,0.79369491,0.778477272 GOTERM_BP_DIRECT,GO:0033574~response to testosterone,11,0.295778435,0.056303972,"GPI1, ADH1, NASP, DUSP1, CDK4, BAD, CAD, TSPO, CAR9, CALR, THBS1",3331,32,18082,1.866012459,1,0.793806514,0.778586737 GOTERM_BP_DIRECT,GO:0051259~protein oligomerization,19,0.510890024,0.056360738,"SH3GLB1, STOML2, NPM1, RRM1, TMED10, AHNAK, AMFR, NME2, KEAP1, GRHPR, OLFM1, PFKL, SNX2, IRAK1, TRIM28, NBR1, CHP1, BAX, BOK",3331,67,18082,1.539396981,1,0.793806514,0.778586737 GOTERM_BP_DIRECT,GO:0051571~positive regulation of histone H3-K4 methylation,7,0.18822264,0.05801926,"DNMT1, SNW1, CTR9, MYB, GCG, OGT, NELFE",3331,16,18082,2.374924947,1,0.802214189,0.78683321 GOTERM_BP_DIRECT,GO:0090303~positive regulation of wound healing,7,0.18822264,0.05801926,"ARFGEF1, REG3A, HMGB1, REG3G, ADRA2A, HBEGF, MYLK",3331,16,18082,2.374924947,1,0.802214189,0.78683321 GOTERM_BP_DIRECT,GO:0000038~very long-chain fatty acid metabolic process,7,0.18822264,0.05801926,"ACOX1, PEX5, ACOT2, HSD17B4, ACAA1A, SLC27A2, SLC27A4",3331,16,18082,2.374924947,1,0.802214189,0.78683321 GOTERM_BP_DIRECT,GO:0010666~positive regulation of cardiac muscle cell apoptotic process,7,0.18822264,0.05801926,"EIF5A, BNIP3, TRP53, CXCR2, GATA6, HMGCR, FBXO32",3331,16,18082,2.374924947,1,0.802214189,0.78683321 GOTERM_BP_DIRECT,GO:0051016~barbed-end actin filament capping,7,0.18822264,0.05801926,"VIL1, DBNL, GSN, CAPZB, CAPZA1, CAPZA2, TWF1",3331,16,18082,2.374924947,1,0.802214189,0.78683321 GOTERM_BP_DIRECT,GO:0045793~positive regulation of cell size,7,0.18822264,0.05801926,"HSP90AA1, HSP90AB1, KDM1A, CDK4, RB1CC1, EP300, OGT",3331,16,18082,2.374924947,1,0.802214189,0.78683321 GOTERM_BP_DIRECT,GO:0030100~regulation of endocytosis,10,0.268889486,0.058159327,"VAMP8, ARHGAP21, RAB4A, RAB4B, HIP1R, ABL2, STON2, SYNJ2BP, RAB5A, PICALM",3331,28,18082,1.938714243,1,0.802214189,0.78683321 GOTERM_BP_DIRECT,GO:0033344~cholesterol efflux,10,0.268889486,0.058159327,"ABCG8, ABCG5, SOAT1, SOAT2, NPC2, APOC2, APOC3, APOA1, APOA4, APOB",3331,28,18082,1.938714243,1,0.802214189,0.78683321 GOTERM_BP_DIRECT,"GO:0000462~maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)",10,0.268889486,0.058159327,"RPS14, MRPS9, EMG1, RPS16, RPS19, RPS8, NGDN, CCDC59, TSR1, RPS24",3331,28,18082,1.938714243,1,0.802214189,0.78683321 GOTERM_BP_DIRECT,GO:0001892~embryonic placenta development,10,0.268889486,0.058159327,"CEBPA, HECTD1, SPINT1, CITED2, SP1, TMED2, HIF1A, EGFR, SLC8A1, BPTF",3331,28,18082,1.938714243,1,0.802214189,0.78683321 GOTERM_BP_DIRECT,GO:0007565~female pregnancy,22,0.59155687,0.058725834,"DDR1, SLC38A1, CYP2J6, SPHK2, CAD, PSG23, FOS, COMT, ADIPOR2, PCSK5, ETS1, EPN1, ADRA2A, CYP2D26, CLDN4, CR1L, NAMPT, UCP2, FOSB, CD38, LGALS9, SLC38A2",3331,81,18082,1.474380214,1,0.806694794,0.791227907 GOTERM_BP_DIRECT,GO:0007050~cell cycle arrest,22,0.59155687,0.058725834,"TCF7L2, CGREF1, ZFHX3, CDC123, CDKN1A, CDKN1B, TSG101, GADD45A, THBS1, PPM1G, TBRG1, ERN2, APC, SGSM3, IRF1, TRP53, MYC, JMY, WDR6, IRF6, CALR, GAS2L1",3331,81,18082,1.474380214,1,0.806694794,0.791227907 GOTERM_BP_DIRECT,GO:0032781~positive regulation of ATPase activity,9,0.242000538,0.059402658,"CHTOP, TPM1, DNAJC10, TOR1AIP2, ATP1B3, DNAJC9, ALDOB, PFN1, ATP1B1",3331,24,18082,2.035649955,1,0.809330907,0.793813478 GOTERM_BP_DIRECT,GO:0006520~cellular amino acid metabolic process,9,0.242000538,0.059402658,"CLN3, GLUD1, DDC, ACY1, GSS, CAD, GOT2, ASL, OTC",3331,24,18082,2.035649955,1,0.809330907,0.793813478 GOTERM_BP_DIRECT,GO:0006805~xenobiotic metabolic process,9,0.242000538,0.059402658,"AKR1C12, SULT1B1, GSTA4, CYP2B10, HNF4A, GSTP1, AKR1C13, NR1I2, RORC",3331,24,18082,2.035649955,1,0.809330907,0.793813478 GOTERM_BP_DIRECT,GO:0006826~iron ion transport,9,0.242000538,0.059402658,"FTL1, HEPH, FTH1, IREB2, SLC11A2, SLC40A1, SFXN1, B2M, SLC39A14",3331,24,18082,2.035649955,1,0.809330907,0.793813478 GOTERM_BP_DIRECT,GO:0061024~membrane organization,18,0.484001076,0.060209242,"RALA, RAB4A, EXOC8, PRKAG1, HIP1R, PRKAG2, DHCR24, ACTB, ACTG1, CLN3, BAIAP2L2, AKT1, CHP1, MYH9, MBP, CALM3, CALM1, CALM2",3331,63,18082,1.550971394,1,0.818649489,0.802953393 GOTERM_BP_DIRECT,GO:0032092~positive regulation of protein binding,19,0.510890024,0.063951329,"TCF7L2, GSK3B, HSP90AB1, HSPA4, USP33, AMFR, DERL1, HIP1R, ARRB1, GCG, TICAM1, SPPL3, HERPUD1, FKBP1A, MAP1LC3B, ABL2, EP300, B2M, RAN",3331,68,18082,1.51675879,1,0.867762337,0.851124593 GOTERM_BP_DIRECT,GO:0000910~cytokinesis,12,0.322667384,0.06464976,"RALA, INCENP, ARL3, PLK1, DCTN3, JTB, BIRC5, MYH9, DSTN, PIK3C3, RHOC, RAB11A",3331,37,18082,1.760562123,1,0.868931868,0.8522717 GOTERM_BP_DIRECT,GO:0031648~protein destabilization,12,0.322667384,0.06464976,"XBP1, NPM1, NCLN, GSN, TMEM147, SRC, FBXW11, PLK1, ID1, DERL1, COMMD1, RNF5",3331,37,18082,1.760562123,1,0.868931868,0.8522717 GOTERM_BP_DIRECT,GO:0050684~regulation of mRNA processing,5,0.134444743,0.06612004,"PTCD2, SLTM, SAFB2, SAFB, CDK11B",3331,9,18082,3.015777711,1,0.868931868,0.8522717 GOTERM_BP_DIRECT,GO:0051983~regulation of chromosome segregation,5,0.134444743,0.06612004,"ZFP207, BUB3, MKI67, PUM1, PUM2",3331,9,18082,3.015777711,1,0.868931868,0.8522717 GOTERM_BP_DIRECT,GO:0042743~hydrogen peroxide metabolic process,5,0.134444743,0.06612004,"PRDX2, CYCS, PARK7, SOD2, EGFR",3331,9,18082,3.015777711,1,0.868931868,0.8522717 GOTERM_BP_DIRECT,GO:0051561~positive regulation of mitochondrial calcium ion concentration,5,0.134444743,0.06612004,"BCAP31, FIS1, MCUR1, MICU2, TGM2",3331,9,18082,3.015777711,1,0.868931868,0.8522717 GOTERM_BP_DIRECT,GO:0043497~regulation of protein heterodimerization activity,5,0.134444743,0.06612004,"CDC42, DUT, BAX, HES1, BAK1",3331,9,18082,3.015777711,1,0.868931868,0.8522717 GOTERM_BP_DIRECT,GO:0007494~midgut development,5,0.134444743,0.06612004,"DAB1, CPS1, REG1, EGFR, OTC",3331,9,18082,3.015777711,1,0.868931868,0.8522717 GOTERM_BP_DIRECT,GO:0042026~protein refolding,5,0.134444743,0.06612004,"HSPA8, HSP90AA1, DNAJA2, B2M, HSPD1",3331,9,18082,3.015777711,1,0.868931868,0.8522717 GOTERM_BP_DIRECT,GO:0071243~cellular response to arsenic-containing substance,5,0.134444743,0.06612004,"DDX3X, GSTO1, UROS, MKNK2, PPIF",3331,9,18082,3.015777711,1,0.868931868,0.8522717 GOTERM_BP_DIRECT,GO:0030042~actin filament depolymerization,5,0.134444743,0.06612004,"VIL1, MICAL1, CFL1, MICAL2, DSTN",3331,9,18082,3.015777711,1,0.868931868,0.8522717 GOTERM_BP_DIRECT,GO:0035308~negative regulation of protein dephosphorylation,5,0.134444743,0.06612004,"PPP1R15A, YWHAE, IGBP1, YWHAB, ARPP19",3331,9,18082,3.015777711,1,0.868931868,0.8522717 GOTERM_BP_DIRECT,GO:0060323~head morphogenesis,5,0.134444743,0.06612004,"MFSD7B, ANKRD11, SSBP3, WNT3, SIDT2",3331,9,18082,3.015777711,1,0.868931868,0.8522717 GOTERM_BP_DIRECT,GO:0002862~negative regulation of inflammatory response to antigenic stimulus,5,0.134444743,0.06612004,"PSMB4, GPX2, GPX1, PSMA1, NLRP6",3331,9,18082,3.015777711,1,0.868931868,0.8522717 GOTERM_BP_DIRECT,GO:0060452~positive regulation of cardiac muscle contraction,5,0.134444743,0.06612004,"CHGA, ACE2, RGS2, HSP90AA1, KCNQ1",3331,9,18082,3.015777711,1,0.868931868,0.8522717 GOTERM_BP_DIRECT,GO:0033234~negative regulation of protein sumoylation,5,0.134444743,0.06612004,"GNL3L, CTNNB1, HMG20B, PARK7, RNF4",3331,9,18082,3.015777711,1,0.868931868,0.8522717 GOTERM_BP_DIRECT,GO:0042787~protein ubiquitination involved in ubiquitin-dependent protein catabolic process,33,0.887335305,0.066819362,"UHRF1, CUL3, UBR4, KEAP1, RCHY1, RNF5, ANAPC11, UBE2L3, HECTD1, HERC2, RMND5A, BTBD1, OS9, HECTD3, BTBD2, SPOP, TRIM25, TCEB1, RBBP6, RNF43, ANKIB1, AMFR, WWP2, UBE4B, RBX1, DDB1, RNF145, RNF126, NEDD4, RNF181, CUL4B, ANAPC2, TAF1",3331,134,18082,1.336844747,1,0.876396981,0.859593684 GOTERM_BP_DIRECT,GO:0019731~antibacterial humoral response,11,0.295778435,0.067949434,"H2-T23, APP, ANG4, DEFA24, ANG, FAU, DEFA20, RPL39, B2M, HIST1H2BC, LTF",3331,33,18082,1.809466627,1,0.885996917,0.869009559 GOTERM_BP_DIRECT,GO:0043523~regulation of neuron apoptotic process,11,0.295778435,0.067949434,"NPM1, EGLN3, GPX1, TRP53, TRIM2, SIGMAR1, G6PDX, PCSK9, BAX, PARK7, GATA3",3331,33,18082,1.809466627,1,0.885996917,0.869009559 GOTERM_BP_DIRECT,GO:0046326~positive regulation of glucose import,11,0.295778435,0.067949434,"MGEA5, PRKCI, RAP1A, PRKCD, ITLN1, AKT1, MIF, MAPK14, ADIPOR2, PRKCZ, NFE2L2",3331,33,18082,1.809466627,1,0.885996917,0.869009559 GOTERM_BP_DIRECT,GO:0045860~positive regulation of protein kinase activity,18,0.484001076,0.068461514,"MAP2K3, NPM1, CDKN1A, SDC4, RPLP1, PXN, PRKAG2, GCG, AXIN2, IQGAP1, PSEN1, DAB1, RAP1A, TRAF4, DAG1, JTB, PTK2B, GAS6",3331,64,18082,1.526737466,1,0.89093385,0.873851835 GOTERM_BP_DIRECT,GO:0043123~positive regulation of I-kappaB kinase/NF-kappaB signaling,36,0.968002151,0.07012594,"BC031181, ANKRD17, CANT1, SLC20A1, CXXC5, LITAF, TRIM8, TFG, IRAK1, NUP62, CASP1, S100A13, ABL2, TRIM25, PIM2, TMED4, TGM2, NDFIP2, UBE2I, SHISA5, TICAM1, RHOC, RHOA, TNFRSF1A, FKBP1A, PPM1A, VAPA, EEF1D, CTH, UBE2N, PELI1, CTNNB1, UBE2V1, LTBR, RBCK1, LTF",3331,149,18082,1.311559703,1,0.910818635,0.893355365 GOTERM_BP_DIRECT,GO:0097192~extrinsic apoptotic signaling pathway in absence of ligand,13,0.349556332,0.072001518,"GSK3B, GSK3A, UNC5A, MAGED1, BAD, MKNK2, CASP2, BAX, BAK1, ITM2B, BCL2L2, BOK, MCL1",3331,42,18082,1.68021901,1,0.930526017,0.912684895 GOTERM_BP_DIRECT,GO:0040008~regulation of growth,19,0.510890024,0.072211338,"MCTS1, TSG101, IGFBP4, PLA2G2A, YEATS4, DLL1, TGFBR1, AES, SOCS2, MORF4L1, NDNL2, MORF4L2, CREG1, EPC1, PHIP, BRD8, GAS6, TKT, PAK2",3331,69,18082,1.494776779,1,0.930526017,0.912684895 GOTERM_BP_DIRECT,GO:0007015~actin filament organization,22,0.59155687,0.073349166,"ACTR3, ACTR2, ARF1, PRKCI, ACTN1, INPPL1, BRK1, WASL, MTSS1, CDC42, DLG1, MYO1B, TMSB4X, CFL1, CTNNA1, FAT1, ABL2, PTK2B, RAC1, TMSB10, DBN1, BCAR1",3331,83,18082,1.43885298,1,0.930526017,0.912684895 GOTERM_BP_DIRECT,GO:0097190~apoptotic signaling pathway,15,0.40333423,0.0734469,"DIDO1, NDUFA13, VDR, BAD, TM2D1, TICAM1, UACA, CD24A, DAP, P2RX4, ANXA6, CASP2, BAX, LTBR, BAK1",3331,51,18082,1.5965882,1,0.930526017,0.912684895 GOTERM_BP_DIRECT,GO:0010800~positive regulation of peptidyl-threonine phosphorylation,9,0.242000538,0.073777833,"GSK3B, GSK3A, CAB39, PLK1, PRKAG2, MAPK1, PHIP, GCG, UBE2K",3331,25,18082,1.954223957,1,0.930526017,0.912684895 GOTERM_BP_DIRECT,GO:0031065~positive regulation of histone deacetylation,6,0.161333692,0.073873396,"SREBF1, NIPBL, NCOR1, CTBP1, TRP53, AKAP8L",3331,13,18082,2.505415329,1,0.930526017,0.912684895 GOTERM_BP_DIRECT,GO:0006661~phosphatidylinositol biosynthetic process,6,0.161333692,0.073873396,"CDS1, IMPA1, INPPL1, PIP5K1B, CDIPT, PI4K2A",3331,13,18082,2.505415329,1,0.930526017,0.912684895 GOTERM_BP_DIRECT,GO:0046889~positive regulation of lipid biosynthetic process,6,0.161333692,0.073873396,"MLXIPL, TCF7L2, AKT1, ABHD6, HSD17B13, DBI",3331,13,18082,2.505415329,1,0.930526017,0.912684895 GOTERM_BP_DIRECT,"GO:0044319~wound healing, spreading of cells",6,0.161333692,0.073873396,"DDR1, CEACAM1, PDCD10, PARD3, RHOC, RHOA",3331,13,18082,2.505415329,1,0.930526017,0.912684895 GOTERM_BP_DIRECT,GO:0042407~cristae formation,6,0.161333692,0.073873396,"LETM1, 2410015M20RIK, CHCHD3, SAMM50, IMMT, TAZ",3331,13,18082,2.505415329,1,0.930526017,0.912684895 GOTERM_BP_DIRECT,GO:0030033~microvillus assembly,6,0.161333692,0.073873396,"VIL1, SLC9A3R1, KLF5, MYO1A, EZR, PLS1",3331,13,18082,2.505415329,1,0.930526017,0.912684895 GOTERM_BP_DIRECT,GO:0016540~protein autoprocessing,6,0.161333692,0.073873396,"PARP1, CTSL, TMPRSS2, PCSK9, CAPN1, PISD",3331,13,18082,2.505415329,1,0.930526017,0.912684895 GOTERM_BP_DIRECT,GO:0033197~response to vitamin E,6,0.161333692,0.073873396,"ALAD, HMGCS1, CCND1, CAT, SRSF2, GSTT1",3331,13,18082,2.505415329,1,0.930526017,0.912684895 GOTERM_BP_DIRECT,GO:0043923~positive regulation by host of viral transcription,6,0.161333692,0.073873396,"JUN, SNW1, SMARCB1, SP1, EP300, NUCKS1",3331,13,18082,2.505415329,1,0.930526017,0.912684895 GOTERM_BP_DIRECT,GO:0031274~positive regulation of pseudopodium assembly,6,0.161333692,0.073873396,"CDC42, APC, CDC42EP5, CDC42EP4, KIT, CDC42EP2",3331,13,18082,2.505415329,1,0.930526017,0.912684895 GOTERM_BP_DIRECT,GO:0051085~chaperone mediated protein folding requiring cofactor,6,0.161333692,0.073873396,"CD74, HSPA8, TOR1B, HSPE1, HSPD1, ERO1L",3331,13,18082,2.505415329,1,0.930526017,0.912684895 GOTERM_BP_DIRECT,GO:0001829~trophectodermal cell differentiation,8,0.215111589,0.07570391,"CDX2, CNOT1, CITED2, CDH1, SP1, CTR9, JUNB, HOPX",3331,21,18082,2.067961859,1,0.948216323,0.930036022 GOTERM_BP_DIRECT,GO:0043393~regulation of protein binding,8,0.215111589,0.07570391,"APP, SRC, APLP2, PLK1, PSEN1, TGFBR1, RAN, HOPX",3331,21,18082,2.067961859,1,0.948216323,0.930036022 GOTERM_BP_DIRECT,GO:0048870~cell motility,8,0.215111589,0.07570391,"CTTN, MYO10, BRK1, RAC1, PLD1, ETS1, IER2, TGFBR1",3331,21,18082,2.067961859,1,0.948216323,0.930036022 GOTERM_BP_DIRECT,GO:0071285~cellular response to lithium ion,7,0.18822264,0.076166416,"CEBPA, GSK3A, CDKN1B, GSTA4, CDH1, NFATC3, CALR",3331,17,18082,2.23522348,1,0.948669768,0.930480773 GOTERM_BP_DIRECT,GO:0061136~regulation of proteasomal protein catabolic process,7,0.18822264,0.076166416,"GPX1, TMF1, PSMD14, UBB, PSME1, PSME2, PRKACA",3331,17,18082,2.23522348,1,0.948669768,0.930480773 GOTERM_BP_DIRECT,GO:1902236~negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway,7,0.18822264,0.076166416,"XBP1, CREB3L1, TMBIM6, PARK7, VIMP, HERPUD1, GRINA",3331,17,18082,2.23522348,1,0.948669768,0.930480773 GOTERM_BP_DIRECT,GO:0030163~protein catabolic process,14,0.376445281,0.078475697,"AMBP, USE1, RBX1, BACE1, BACE2, PSMC5, PSMC6, PSMC3, PSMB3, PSMC4, PSMC1, LONP1, AKT1, CTSD",3331,47,18082,1.616970177,1,0.957996549,0.939628731 GOTERM_BP_DIRECT,GO:0070585~protein localization to mitochondrion,4,0.107555795,0.080359207,"DNAJA1, MTCH2, BAG1, MARCH5",3331,6,18082,3.618933253,1,0.957996549,0.939628731 GOTERM_BP_DIRECT,GO:0006047~UDP-N-acetylglucosamine metabolic process,4,0.107555795,0.080359207,"GFPT1, UAP1, B4GALNT2, GNE",3331,6,18082,3.618933253,1,0.957996549,0.939628731 GOTERM_BP_DIRECT,GO:0090166~Golgi disassembly,4,0.107555795,0.080359207,"GOLGA2, GBF1, CDK1, STX5A",3331,6,18082,3.618933253,1,0.957996549,0.939628731 GOTERM_BP_DIRECT,GO:0042987~amyloid precursor protein catabolic process,4,0.107555795,0.080359207,"APH1A, CLN3, DHCR24, PSEN1",3331,6,18082,3.618933253,1,0.957996549,0.939628731 GOTERM_BP_DIRECT,GO:0070508~cholesterol import,4,0.107555795,0.080359207,"STARD4, STARD5, APOA1, LDLR",3331,6,18082,3.618933253,1,0.957996549,0.939628731 GOTERM_BP_DIRECT,GO:0002003~angiotensin maturation,4,0.107555795,0.080359207,"ACE2, ENPEP, ATP6AP2, SIDT2",3331,6,18082,3.618933253,1,0.957996549,0.939628731 GOTERM_BP_DIRECT,GO:0033119~negative regulation of RNA splicing,4,0.107555795,0.080359207,"RPS26, PTBP1, RPS13, PTBP3",3331,6,18082,3.618933253,1,0.957996549,0.939628731 GOTERM_BP_DIRECT,GO:1901029~negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway,4,0.107555795,0.080359207,"ACAA2, MPV17L, SLC25A5, BOK",3331,6,18082,3.618933253,1,0.957996549,0.939628731 GOTERM_BP_DIRECT,GO:0019243~methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione,4,0.107555795,0.080359207,"PNKD, GLO1, PARK7, HAGH",3331,6,18082,3.618933253,1,0.957996549,0.939628731 GOTERM_BP_DIRECT,GO:0007007~inner mitochondrial membrane organization,4,0.107555795,0.080359207,"CHCHD3, MYC, BAX, TAZ",3331,6,18082,3.618933253,1,0.957996549,0.939628731 GOTERM_BP_DIRECT,GO:0051084~'de novo' posttranslational protein folding,4,0.107555795,0.080359207,"SH3GLB1, SEP15, ENTPD5, UGGT1",3331,6,18082,3.618933253,1,0.957996549,0.939628731 GOTERM_BP_DIRECT,GO:0060789~hair follicle placode formation,4,0.107555795,0.080359207,"CDC42, HDAC1, GNAS, CTNNB1",3331,6,18082,3.618933253,1,0.957996549,0.939628731 GOTERM_BP_DIRECT,GO:0034975~protein folding in endoplasmic reticulum,4,0.107555795,0.080359207,"EMC1, DNAJC10, EMC6, ERO1L",3331,6,18082,3.618933253,1,0.957996549,0.939628731 GOTERM_BP_DIRECT,GO:0030203~glycosaminoglycan metabolic process,4,0.107555795,0.080359207,"HEXB, HEXA, GNS, CLN6",3331,6,18082,3.618933253,1,0.957996549,0.939628731 GOTERM_BP_DIRECT,GO:0051054~positive regulation of DNA metabolic process,4,0.107555795,0.080359207,"MGEA5, NPM1, PFN1, IGF1R",3331,6,18082,3.618933253,1,0.957996549,0.939628731 GOTERM_BP_DIRECT,GO:0006613~cotranslational protein targeting to membrane,4,0.107555795,0.080359207,"TRAM1, ARL6IP1, SSR2, SSR1",3331,6,18082,3.618933253,1,0.957996549,0.939628731 GOTERM_BP_DIRECT,GO:0006104~succinyl-CoA metabolic process,4,0.107555795,0.080359207,"SUCLA2, OGDH, SUCLG2, SUCLG1",3331,6,18082,3.618933253,1,0.957996549,0.939628731 GOTERM_BP_DIRECT,GO:0046033~AMP metabolic process,4,0.107555795,0.080359207,"AK2, AK3, AK4, AMPD2",3331,6,18082,3.618933253,1,0.957996549,0.939628731 GOTERM_BP_DIRECT,GO:0010324~membrane invagination,4,0.107555795,0.080359207,"SNX3, CHMP2A, WASL, FNBP1L",3331,6,18082,3.618933253,1,0.957996549,0.939628731 GOTERM_BP_DIRECT,"GO:0042769~DNA damage response, detection of DNA damage",4,0.107555795,0.080359207,"DNAJA1, PARP1, RPS3, SOX4",3331,6,18082,3.618933253,1,0.957996549,0.939628731 GOTERM_BP_DIRECT,GO:0008635~activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c,4,0.107555795,0.080359207,"CYCS, BAX, BAK1, BOK",3331,6,18082,3.618933253,1,0.957996549,0.939628731 GOTERM_BP_DIRECT,GO:1903715~regulation of aerobic respiration,4,0.107555795,0.080359207,"VCP, BNIP3, HIF1A, CBFA2T3",3331,6,18082,3.618933253,1,0.957996549,0.939628731 GOTERM_BP_DIRECT,GO:0030299~intestinal cholesterol absorption,4,0.107555795,0.080359207,"ABCG8, ABCG5, NPC1L1, LDLR",3331,6,18082,3.618933253,1,0.957996549,0.939628731 GOTERM_BP_DIRECT,GO:0060612~adipose tissue development,11,0.295778435,0.081016544,"ATF2, XBP1, UBB, OXCT1, SELM, CDK4, ADRM1, RORC, ARID5B, AACS, ACAT1",3331,34,18082,1.75624702,1,0.962395816,0.943943649 GOTERM_BP_DIRECT,GO:0015914~phospholipid transport,11,0.295778435,0.081016544,"ABCG8, TMEM30A, SCP2, STARD7, ATP8B1, MTTP, PITPNA, STARD10, APOA1, LDLR, ATP9A",3331,34,18082,1.75624702,1,0.962395816,0.943943649 GOTERM_BP_DIRECT,GO:0048813~dendrite morphogenesis,13,0.349556332,0.083831945,"ITGB1, RERE, ROCK2, KIDINS220, MINK1, SLC11A2, CACNA1A, HPRT, DVL1, ABI1, ABL2, RAC1, PICALM",3331,43,18082,1.64114415,1,0.992308623,0.973282933 GOTERM_BP_DIRECT,GO:0045740~positive regulation of DNA replication,13,0.349556332,0.083831945,"NPM1, JUN, PCNA, PDGFA, CACYBP, TNFAIP1, EGFR, IGF1R, CST3, CDC42, CDK1, RAC1, CALR",3331,43,18082,1.64114415,1,0.992308623,0.973282933 GOTERM_BP_DIRECT,GO:0042752~regulation of circadian rhythm,15,0.40333423,0.084183384,"TOP2A, KLF10, MAGED1, ROCK2, FBXW11, NONO, CSNK1D, RORB, ADCY1, PPP1CA, PPP1CB, PPP1CC, SFPQ, HNRNPD, PPARA",3331,52,18082,1.565884581,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:0010975~regulation of neuron projection development,10,0.268889486,0.085611442,"SNAP25, GSK3B, DPYSL2, PTEN, AKT1, PAX6, GATA3, PAK3, PTPRF, RHOA",3331,30,18082,1.809466627,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:0032880~regulation of protein localization,18,0.484001076,0.08716307,"TMEM184A, RAB9, PRNP, MYCBP2, WASL, CELSR3, FKBP1A, RSL1D1, DLG1, RAB14, DNAJB6, MYO1A, CDH1, ARHGDIA, MYO5B, AKT1, RAB8A, PICALM",3331,66,18082,1.480472695,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:0006461~protein complex assembly,18,0.484001076,0.08716307,"CD74, ZFP148, GCH1, GMNN, SLC2A1, VAMP8, GCHFR, APC, PPP2R1A, TRP53, CDK1, HES1, SOX9, NUPR1, SSBP3, PPID, VAMP3, MAPK3",3331,66,18082,1.480472695,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:0048661~positive regulation of smooth muscle cell proliferation,21,0.564667921,0.087527135,"EGR1, GSK3B, JUN, CYBA, PRKCA, HMGCR, THBS1, HIF1A, EGFR, CX3CL1, IGF1R, VEGFA, FOXP1, IRAK1, MYC, GNAQ, NAMPT, AKT1, RAB5A, HBEGF, TGM2",3331,80,18082,1.424954968,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:0031440~regulation of mRNA 3'-end processing,3,0.080666846,0.089238372,"AHCYL1, PAPOLA, ZFP36L1",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:0018125~peptidyl-cysteine methylation,3,0.080666846,0.089238372,"RAB3B, RAB3D, RAB6A",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:0001732~formation of cytoplasmic translation initiation complex,3,0.080666846,0.089238372,"CDC123, EIF3D, EIF3A",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,"GO:0019287~isopentenyl diphosphate biosynthetic process, mevalonate pathway",3,0.080666846,0.089238372,"MVK, PMVK, MVD",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:0060319~primitive erythrocyte differentiation,3,0.080666846,0.089238372,"LDB1, ZFPM1, VEGFA",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:0090240~positive regulation of histone H4 acetylation,3,0.080666846,0.089238372,"SMARCB1, PIH1D1, ARRB1",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:2000984~negative regulation of ATP citrate synthase activity,3,0.080666846,0.089238372,"CHCHD10, GBAS, PHPT1",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:0060856~establishment of blood-brain barrier,3,0.080666846,0.089238372,"LSR, ABCB1A, MFSD2A",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:1990928~response to amino acid starvation,3,0.080666846,0.089238372,"EIF4EBP1, EIF2B1, EIF2A",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:0000454~snoRNA guided rRNA pseudouridine synthesis,3,0.080666846,0.089238372,"DKC1, GAR1, NOP10",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:0019240~citrulline biosynthetic process,3,0.080666846,0.089238372,"CAD, ALDH18A1, OTC",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:0009113~purine nucleobase biosynthetic process,3,0.080666846,0.089238372,"SHMT1, PPAT, GART",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:0000189~MAPK import into nucleus,3,0.080666846,0.089238372,"TPR, MAPK1, MAPK3",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:0046185~aldehyde catabolic process,3,0.080666846,0.089238372,"GPI1, ALDH3B1, AKR1A1",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:0031120~snRNA pseudouridine synthesis,3,0.080666846,0.089238372,"DKC1, NHP2, NOP10",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,"GO:1904154~positive regulation of retrograde protein transport, ER to cytosol",3,0.080666846,0.089238372,"BCAP31, EDEM1, EDEM2",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:1902896~terminal web assembly,3,0.080666846,0.089238372,"VIL1, EZR, PLS1",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:0006624~vacuolar protein processing,3,0.080666846,0.089238372,"TMEM208, VPS35, LGMN",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:0030575~nuclear body organization,3,0.080666846,0.089238372,"CELF3, NEAT1, SF1",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,"GO:0019254~carnitine metabolic process, CoA-linked",3,0.080666846,0.089238372,"ACADL, ACADM, CRAT",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:0031118~rRNA pseudouridine synthesis,3,0.080666846,0.089238372,"DKC1, NHP2, NOP10",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:0008356~asymmetric cell division,3,0.080666846,0.089238372,"ACTR3, GOLGA2, ACTR2",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:0061308~cardiac neural crest cell development involved in heart development,3,0.080666846,0.089238372,"CITED2, MAPK1, MAPK3",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:0061623~glycolytic process from galactose,3,0.080666846,0.089238372,"GALE, GALT, GALK1",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:0046985~positive regulation of hemoglobin biosynthetic process,3,0.080666846,0.089238372,"LDB1, PRMT1, KLF4",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:1904970~brush border assembly,3,0.080666846,0.089238372,"MYO7B, USH1C, ANKS4B",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,"GO:0009051~pentose-phosphate shunt, oxidative branch",3,0.080666846,0.089238372,"G6PDX, PGLS, PGD",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:2000825~positive regulation of androgen receptor activity,3,0.080666846,0.089238372,"BUD31, PARK7, TAF1",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:0061684~chaperone-mediated autophagy,3,0.080666846,0.089238372,"CTSA, HSPA8, LAMP2",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:0051702~interaction with symbiont,3,0.080666846,0.089238372,"DDB1, GPX2, GPX1",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:0044337~canonical Wnt signaling pathway involved in positive regulation of apoptotic process,3,0.080666846,0.089238372,"GSK3B, APC, MYC",3331,3,18082,5.42839988,1,0.992925618,0.973888099 GOTERM_BP_DIRECT,GO:0007040~lysosome organization,12,0.322667384,0.08951728,"CLN3, FAM160A2, HOOK2, GAA, HEXB, HEXA, PPT1, HPS4, TPP1, LAMTOR1, CLN6, CHMP5",3331,39,18082,1.670276886,1,0.994371646,0.975306402 GOTERM_BP_DIRECT,GO:0001954~positive regulation of cell-matrix adhesion,9,0.242000538,0.090070237,"CCL25, GSK3B, NINJ1, DAG1, PTK2B, CIB1, UTRN, CCL28, PRKCZ",3331,26,18082,1.879061497,1,0.99719553,0.978076143 GOTERM_BP_DIRECT,GO:0046513~ceramide biosynthetic process,9,0.242000538,0.090070237,"SMPD2, CERS4, SPTLC1, SPTLC2, DEGS1, SPTSSA, DEGS2, SGMS2, CERS2",3331,26,18082,1.879061497,1,0.99719553,0.978076143 GOTERM_BP_DIRECT,GO:0050766~positive regulation of phagocytosis,14,0.376445281,0.090257851,"HSPA8, CAMK1D, RAB27A, CYBA, RAP1GAP, DNM2, PYCARD, ABR, RAP1A, LMAN2, CD47, CALR, MFGE8, GAS6",3331,48,18082,1.583283298,1,0.997618231,0.978490739 GOTERM_BP_DIRECT,GO:0045665~negative regulation of neuron differentiation,20,0.537778973,0.094053268,"ITGB1, APP, DDX6, CASZ1, BEX1, LSM1, PAX6, PRPF19, FUOM, DLL1, RTN4, RHOA, RAP1GAP, PBX1, CD24A, LMX1A, HES1, CALR, NKX2-2, FOXA2",3331,76,18082,1.428526284,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0006928~movement of cell or subcellular component,8,0.215111589,0.094098087,"STRBP, PXN, CFL1, ABI1, MYH9, CD9, DSTN, SH2B1",3331,22,18082,1.973963593,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0015893~drug transport,5,0.134444743,0.09460093,"ABCC3, SLC22A18, ABCB1A, SLC18A1, SLC18A2",3331,10,18082,2.71419994,1,1,0.980973783 GOTERM_BP_DIRECT,GO:1902188~positive regulation of viral release from host cell,5,0.134444743,0.09460093,"DDB1, TSG101, CHMP2B, CHMP2A, CHMP4B",3331,10,18082,2.71419994,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0006596~polyamine biosynthetic process,5,0.134444743,0.09460093,"ODC1, OAZ1, OAZ2, AZIN1, SRM",3331,10,18082,2.71419994,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0033762~response to glucagon,5,0.134444743,0.09460093,"QDPR, CCNA2, SREBF1, CYC1, CDO1",3331,10,18082,2.71419994,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0030851~granulocyte differentiation,5,0.134444743,0.09460093,"CEBPA, KDM1A, CITED2, ZFPM1, CBFA2T3",3331,10,18082,2.71419994,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0071786~endoplasmic reticulum tubular network organization,5,0.134444743,0.09460093,"RAB10, RTN3, TMEM33, USE1, RTN4",3331,10,18082,2.71419994,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0043653~mitochondrial fragmentation involved in apoptotic process,5,0.134444743,0.09460093,"ATG3, FIS1, BNIP3, BAX, MFF",3331,10,18082,2.71419994,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0060765~regulation of androgen receptor signaling pathway,5,0.134444743,0.09460093,"DDX5, SAFB2, EP300, RNF6, PARK7",3331,10,18082,2.71419994,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0007270~neuron-neuron synaptic transmission,5,0.134444743,0.09460093,"PTEN, VDAC3, CACNA1A, KIF1B, VDAC1",3331,10,18082,2.71419994,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0033673~negative regulation of kinase activity,5,0.134444743,0.09460093,"PRPSAP1, PRDX3, CDKN1B, WNK1, CSK",3331,10,18082,2.71419994,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0009062~fatty acid catabolic process,5,0.134444743,0.09460093,"FAAH, ACADVL, ACADL, ECH1, LPIN2",3331,10,18082,2.71419994,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0006268~DNA unwinding involved in DNA replication,5,0.134444743,0.09460093,"TOP2A, PURB, MCM7, MCM6, MCM2",3331,10,18082,2.71419994,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0046902~regulation of mitochondrial membrane permeability,5,0.134444743,0.09460093,"BAD, BNIP3, STAT3, PPIF, BAK1",3331,10,18082,2.71419994,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0017145~stem cell division,5,0.134444743,0.09460093,"TIAL1, CUL3, FUBP1, MYB, PAFAH1B1",3331,10,18082,2.71419994,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0010898~positive regulation of triglyceride catabolic process,5,0.134444743,0.09460093,"AADAC, APOC2, APOA1, APOA4, PNPLA2",3331,10,18082,2.71419994,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0006325~chromatin organization,13,0.349556332,0.096805044,"GPX4, HDAC1, EHMT1, NUCKS1, CHD4, ARID1A, SMARCA2, MORF4L1, HMGN5, MORF4L2, UBN1, HMG20B, HMGN1",3331,44,18082,1.603845419,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0019752~carboxylic acid metabolic process,7,0.18822264,0.097144473,"MCFD2, DDC, LDHA, MDH1, PDXDC1, MDH2, MIF",3331,18,18082,2.111044398,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0001678~cellular glucose homeostasis,7,0.18822264,0.097144473,"TCF7L2, HKDC1, NUCKS1, PIK3R1, MYT1, FOXA3, HK2",3331,18,18082,2.111044398,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0051149~positive regulation of muscle cell differentiation,7,0.18822264,0.097144473,"EIF5A, CDC42, SETD3, TCF3, MAPK14, CDO1, NEO1",3331,18,18082,2.111044398,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0001676~long-chain fatty acid metabolic process,7,0.18822264,0.097144473,"CPT1A, ACSL6, ACOT2, ACOT1, PAM, SLC27A2, SLC27A4",3331,18,18082,2.111044398,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0050860~negative regulation of T cell receptor signaling pathway,7,0.18822264,0.097144473,"DUSP22, PRNP, CEACAM1, ELF1, BTNL2, EZR, PHPT1",3331,18,18082,2.111044398,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0051000~positive regulation of nitric-oxide synthase activity,7,0.18822264,0.097144473,"GCH1, AKT1, PTK2B, CALM3, KRAS, CALM1, CALM2",3331,18,18082,2.111044398,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0055093~response to hyperoxia,7,0.18822264,0.097144473,"POLB, CDKN1A, CDK4, BNIP3, TRP53, CAT, SOD2",3331,18,18082,2.111044398,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0090263~positive regulation of canonical Wnt signaling pathway,18,0.484001076,0.097635863,"THRA, SRC, USP34, CSNK1D, NFKB1, CTDNEP1, LMX1A, TNKS2, DVL1, PIN1, VPS35, FGFR3, LGR5, SOX4, LGR4, RNF220, WLS, TRPM4",3331,67,18082,1.458376087,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0006656~phosphatidylcholine biosynthetic process,6,0.161333692,0.098114713,"CHKB, FABP5, CHKA, APOA1, CHPT1, CEPT1",3331,14,18082,2.326457091,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0097284~hepatocyte apoptotic process,6,0.161333692,0.098114713,"MTCH2, GSN, KRT18, DNMT3A, KRT8, ARF6",3331,14,18082,2.326457091,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0006855~drug transmembrane transport,6,0.161333692,0.098114713,"ABCC3, TMEM30A, ABCC2, SLC31A1, ATP8B1, ABCB1A",3331,14,18082,2.326457091,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0043069~negative regulation of programmed cell death,6,0.161333692,0.098114713,"BNIP3L, DNAJA3, NUP62, AMIGO2, KIT, VEGFA",3331,14,18082,2.326457091,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0010839~negative regulation of keratinocyte proliferation,6,0.161333692,0.098114713,"EFNB2, VDR, CTSL, CASK, EPPK1, PTPRK",3331,14,18082,2.326457091,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0060081~membrane hyperpolarization,6,0.161333692,0.098114713,"CASP1, ATP1A1, PARK7, PRKCZ, SLC26A3, CFTR",3331,14,18082,2.326457091,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0001817~regulation of cytokine production,6,0.161333692,0.098114713,"ELF1, CSK, IQGAP1, F11R, LITAF, LTF",3331,14,18082,2.326457091,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0006839~mitochondrial transport,6,0.161333692,0.098114713,"MFSD7B, KIF5B, UCP2, SLC25A10, PSEN1, TMEM14C",3331,14,18082,2.326457091,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0050765~negative regulation of phagocytosis,6,0.161333692,0.098114713,"SNX3, ATG3, SYT11, PTEN, CSK, ATG5",3331,14,18082,2.326457091,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0030516~regulation of axon extension,6,0.161333692,0.098114713,"OLFM1, GSK3B, CTTN, DPYSL2, MGLL, DNM2",3331,14,18082,2.326457091,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0016485~protein processing,22,0.59155687,0.099586165,"PSENEN, PCSK1, PCSK9, ECE1, FURIN, PSEN1, PCSK5, APH1A, CLN3, CASP7, NRD1, CTSL, CPD, MYC, UQCRC1, CASP1, CPE, CASP2, PMPCB, PIK3C3, UQCRC2, METAP2",3331,86,18082,1.388660434,1,1,0.980973783 GOTERM_BP_DIRECT,GO:0008360~regulation of cell shape,33,0.887335305,0.099687782,"HEXB, PXN, ARHGAP18, LIMD1, MYL12A, MYL12B, GNA13, SLC9A3R1, ARHGDIA, S100A13, MYH14, PTK2B, SEMA4A, MYO10, CSNK1A1, TPM1, SHROOM3, CSNK1D, VEGFA, VIL1, DLG1, CFDP1, CDC42EP5, CDC42EP4, KIT, CDC42EP2, PLXNB2, MYH9, RHOU, PHIP, EZR, ALDOA, GAS7",3331,139,18082,1.288756806,1,1,0.980973783