Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_MF_DIRECT,GO:0044822~poly(A) RNA binding,538,14.46625437,1.33E-123,"RPL4, RPL5, TES, RPL3, RPL32, TFRC, RPL31, DQX1, RRP1, HNRNPU, ATP5C1, HNRNPR, RPL8, RPL6, RPL7, ALKBH5, PSMD4, RPL36, RPL35, DDX17, MBNL1, MBNL2, RPL21, RPL23, NGDN, RPL22, DNTTIP2, FNDC3A, GTPBP1, SND1, RC3H2, GTPBP4, DDX39B, EWSR1, CLNS1A, SARNP, ZC3H11A, RPL24, RPL27, RPL28, H2-D1, SF1, C4BP, SLBP, RPN1, NOLC1, MRPL14, MRPL15, MRPL13, GIGYF2, MRPL10, MRPL11, RRP7A, MRPL20, LARP1, S100A16, PRDX1, GAR1, LTA4H, BTF3, JUN, PRPF38B, PNO1, MRPL27, MRPL28, PRRC2C, UPF3B, PA2G4, LARP4, 5330417C22RIK, PRRC2B, EIF1, PRRC2A, HNRNPL, CS, MOV10, HNRNPM, HNRNPK, EIF5, HNRNPF, FASN, HNRNPD, HNRNPC, FARSA, SMG1, ARF1, RPLP0, CLTC, SRPR, ADK, MRPL37, MRPL42, CSRP1, NELFE, ANXA2, NSUN2, NUDT16L1, MRPL45, MRPL43, GNL3, HADHB, NSA2, CDC42EP4, TCP1, SF3B4, GRN, SF3B2, RPL10, AHNAK, NIP7, RPL12, RPL11, ATP5A1, USO1, SRRT, RPS27L, BCLAF1, RPS15A, SRP72, TCOF1, RPS3, RPL14, RPL13, FLNB, RPS2, RPL15, RPS27A, RPL17, SRSF10, SF3B1, SRSF11, RPL19, SF3A3, YTHDF1, SF3A1, MDH2, TRMT1, SRP68, LRPPRC, KTN1, ARCN1, PHF5A, MYBBP1A, PSMC1, SERBP1, ZYX, TSR1, UBAP2, PKN2, ZFP207, H2-K1, MSI2, APEH, RPL10A, BZW1, IPO5, PPP1CC, ZFP36, HMGN5, FBRSL1, KPNA2, SLC16A3, RPS9, RPS7, RPS8, EIF1AX, RPS5, RPS6, RPSA, LARP4B, EBNA1BP2, ILF3, NCL, MRTO4, NHP2, SRSF2, SRSF3, ERH, SRSF5, SNRNP200, SRSF6, FKBP4, SRSF7, KPNB1, SNRPB, SRSF9, ANKRD17, ZFP106, KHDRBS1, LRRC59, PEF1, GTF2E2, STIP1, G3BP1, TPR, G3BP2, SAFB2, BRIX1, TIA1, CHTOP, FUS, GOT2, FAM103A1, LSM1, EEF2, LSM4, LSM2, CHERP, CNOT4, SON, GNL3L, LSM6, CNOT1, PIN4, EIF4G2, EIF4G1, DIDO1, HSP90AB1, AKAP8L, DUSP11, MRPL4, NGRN, RPL7A, PTBP1, MRPL3, MRPL2, MRPL1, SUMO1, SNRNP70, SUMO2, UBTF, WDR6, MRPL9, LBR, DSP, EIF5A, EIF5B, HSP90AA1, RPL13A, EDF1, PTBP3, DNAJC2, PKM, RPL37A, ETF1, SNRPA1, RP9, TOP1, EIF4E2, SLC25A5, SLC25A11, ROCK2, SRSF1, H2-Q4, H2-Q1, HSD17B10, PUF60, U2AF2, POLR2B, EIF4H, RBBP6, IGF2BP2, EIF4B, HNRNPA0, NOP56, DUT, NOP58, SSB, CNBP, CCDC59, RPL35A, IMMT, HNRNPAB, TPD52L2, EIF3L, RPS3A1, EIF3G, ESF1, EIF3H, CEBPZ, EIF3E, P4HB, EIF3C, EIF3D, EIF3A, TNRC6A, TPT1, TNRC6B, METAP2, EIF4A2, EIF4A1, EIF4A3, CISD2, MKI67, CRKL, UBE2L3, CCAR1, TIAL1, RPS15, PNN, RPS14, RPS17, RPS16, RPL18A, SNRPD2, TRIM28, RPS19, SNRPD1, RPS18, MAGOH, ARL6IP4, TRIM25, UBAP2L, SNRPD3, RPS11, RPS10, RPS13, SEC63, RPS12, SRRM2, IMP3, SCAF11, CIRBP, ACTN4, SRRM1, SUB1, XRN2, TFAM, SUCLG1, KCTD12, PFN1, EIF1A, EZR, EIF1B, ZFP622, DHX9, STXBP1, GSPT1, DHX32, PCBP1, PCBP2, HLTF, DHX36, SPTBN1, TRAP1, RCC2, PUM1, PUM2, MANF, CCT6A, RPS26, RPS25, RPS28, SNW1, FUBP1, RPL27A, GOLGB1, NOL10, RNPS1, RPS20, CALR, ALDH18A1, NOL12, RPS21, RPS24, RPS23, TOP2A, ZCCHC11, DAZAP1, MRPS15, MRPS14, PPP1R10, GDI2, MRPS12, PCSK9, LARP1B, SYNCRIP, DHX15, SEC61B, CCT3, MRPS28, MRPS26, MRPS24, PARP1, NCOA5, PRMT1, STRBP, PABPC4, MRPS23, ZFR, MRPS21, MRPS7, GLTSCR2, MRPS5, NME1, MRPS9, SLTM, NHP2L1, HNRNPH1, CSDE1, CANX, FRG1, STRAP, HNRNPH2, PABPC1, MAPRE1, ALDOA, NOL7, MRPS31, PURB, CTNNA1, CCT4, DYNC1H1, NQO1, NPM1, FAM46A, RSRC2, RSL1D1, KRT18, HNRNPA2B1, EPPK1, HDGF, FAU, TARDBP, TXN1, ACAA2, HDLBP, BCCIP, PEBP1, NUCKS1, SRP14, FBL, KHSRP, CHCHD1, PDIA3, 2700094K13RIK, UTP11L, WBP11, TUFM, EEF1A1, HNRNPUL2, DKC1, SCG3, MATR3, PPIG, PPIB, PPIA, ZCCHC7, DDX6, VCP, DDX5, RBM8A, YTHDC1, DDX1, PRPF8, ZFP36L2, RTN4, ZFP36L1, EMG1, UBC, ZC3H18, NDUFV3, LLPH, MARK2, ZC3H15, HSPA9, HSPA8, FDPS, CPSF7, CPSF6, UBE2I, NONO, TBCA, EIF2S2, EIF2S1, H1F0, CAPRIN1, UBE2N, UBA1, LSM14A, YWHAE, DDX3X, DDX46, HMGB2, ADAR, YBX1, CHD3, YBX3, ELAVL1, RBM3, RPS4X, MYO18A, RBM34, YWHAG, HIST1H1C, TSFM, RBM14, GLRX3, NCBP2, DDX54, SAFB, YWHAZ, DNM1, SFPQ, THRAP3, LUC7L3, MYH9, SKIV2L2, LUC7L2, PLEC, RBM47, DDX27, DDX24, USP10, DDX21, SLC3A2, RRBP1, HSPD1, TBRG4, PABPN1, TRA2B, FAM120A, TRA2A, ABCF1, PTCD3, DDX39, RBM39, PTCD2, PDAP1, NAP1L1, SSRP1, HSPE1, U2SURP, 2700060E02RIK, ACIN1, SSBP1, SLIRP, RAN",3206,1113,17446,2.630385861,2.94E-120,2.94E-120,2.82E-120
GOTERM_MF_DIRECT,GO:0098641~cadherin binding involved in cell-cell adhesion,158,4.248453885,3.06E-46,"TES, CTNND1, HDLBP, PARK7, F11R, BZW2, BZW1, RPL6, CRKL, GOLGA2, SLK, CDH1, PPME1, KIF5B, BSG, TRIM25, TMPO, SH3GL1, EIF2A, SH3GLB1, CSNK1D, SND1, HCFC1, CHMP4B, RPL24, TAGLN2, PKP3, EZR, PFN1, PHLDB2, DDX6, LRRC59, TXNDC9, PDXDC1, TWF1, ARHGAP18, IQGAP1, NDRG1, GIGYF2, RTN4, CORO1B, CNN3, SDCBP, CCNB2, SNX1, LDHA, LARP1, SNX2, PRDX1, PCBP1, MYO6, STK38, PACSIN2, EIF2S3X, ARGLU1, SPTBN1, SNX5, MARK2, VASP, HSPA8, JUP, HSPA5, IDH1, CGN, EEF2, PRDX6, PAICS, EHD1, RPS26, DLG1, EIF5, HNRNPK, STK24, FASN, CHMP2B, EIF4G2, EIF4G1, PICALM, ITGB1, YWHAE, LAD1, DDX3X, HSP90AB1, YWHAB, ARHGAP1, OLA1, CLINT1, RPL7A, SEPT9, LASP1, ATIC, CAPZB, RARS, EFHD2, ERC1, CLIC1, MKL2, NUDC, DBNL, ANXA2, ARHGEF16, AHSA1, RANGAP1, YWHAZ, EEF1G, PLCB3, PKM, GPRC5A, CTTN, EEF1D, PLIN3, MYH9, STX5A, MAPRE1, ALDOA, DBN1, PLEC, CHMP5, AHNAK, SRC, USO1, SLC3A2, EGFR, FAM129B, PDLIM1, PSMB6, LIMA1, PUF60, EPCAM, RPL14, CTNNA1, EIF4H, EPS8L2, FLNB, RPS2, RPL15, CCT8, PDLIM5, PAK2, NOP56, RANBP1, RAB11B, RAB10, RSL1D1, MYO1B, KRT18, VAPA, CAPZA1, GLOD4, ABI1, SERBP1, CTNNB1, PKN2, UBAP2, EIF3E, PFKP, RAN, TJP2",3206,279,17446,3.081663637,6.77E-43,3.39E-43,3.25E-43
GOTERM_MF_DIRECT,GO:0005515~protein binding,1046,28.12584028,5.19E-40,"ATF2, TFRC, EHMT2, ARAF, EHMT1, F11R, CLDN2, LIPE, PPP4R2, SCP2, DPYSL2, PSMD2, GPBP1, PSMD3, PSMD1, AKT1, PRKACA, WLS, FNBP4, GABARAPL2, GABARAPL1, CXADR, CACNA2D1, HPCAL1, SCAMP1, RC3H2, SND1, EID1, CLDN4, RBP4, MYL6, CLDN3, RFX6, PRKAR1A, EWSR1, CLDN7, PSME1, UQCRC1, PSME2, TXNIP, TBPL1, ATF5, ATF6, OPTN, ATF4, FLII, GATA6, BAZ2A, GATA3, IQGAP1, OAZ1, GIGYF2, GABARAP, OAZ2, CYB5R3, KCNQ1OT1, PRKAR2A, MYO6, PIP5K1B, LTA4H, VTI1B, ATG5, JUN, GSTM1, JUP, EDEM1, PBX1, MOV10, FXYD3, FAT1, ARF4, ARF1, ARHGAP1, BHLHE41, CTCF, LITAF, TUBA1B, UCN3, SLC18A2, JAK1, DLGAP4, CNOT6L, DYNLL1, BAZ1B, DYNLL2, MED28, VAMP8, PSMA3, MED25, GPRC5A, PSMA1, SLC7A9, TMEM33, CDC42EP5, CDC42EP4, PELI1, PICK1, HAP1, PPARA, ARF5, PAFAH1B1, RAPGEF4, ARF6, VAMP3, TMF1, ATP5A1, SRRT, EGFR, NEURL1B, TMEM65, SPOP, MICALL2, FLNB, STX3, MBD3, USP9X, STAT3, MBD2, TARBP2, PSMC5, MYBBP1A, SNX17, PKN2, FRYL, LGR4, PDCD6, CSE1L, GMNN, UBE2D3, FBXO25, RORC, RORB, YY1, SLK, NRD1, RUVBL2, KPNA6, PIM3, CIR1, PIM2, KPNA2, SH2D5, SH3GLB1, BNIP3L, S100A1, STX7, TICAM1, NEAT1, MYT1, FOXP1, RBX1, OLFM1, RBMXL1, MAPKAPK2, S100A6, SRSF2, PKP3, SRSF5, SRSF6, UTRN, SRSF7, SQSTM1, ANAPC1, KPNB1, KHDRBS1, ARL3, CORO1B, RAP1GAP, HSP90B1, RAP1B, SLC9A3R1, RAP1A, STK38, G3BP1, EIF4EBP1, SMYD2, SMYD3, FBXO32, EEF2, NFKB1, PTPRD, YRDC, MLXIPL, SON, RGCC, SERPINB6A, ARPC2, SP1, PIN1, OGT, NOP10, NFE2L1, H2-AB1, NFE2L2, ITGB1, UFD1L, SNAP25, HSP90AB1, PTEN, FHL2, FHL3, ETFA, ARRB1, CAPZB, SUMO1, ERC1, NEO1, BOK, ACTR3, DSP, HSP90AA1, DST, ITGA3, ATRX, RAD23B, TNFRSF1A, QTRT1, ATRN, HAX1, BIRC5, PIK3C3, LCP1, SLC25A4, SEC23A, ROCK1, SRC, ROCK2, UHRF1, USH1C, FURIN, PPM1J, U2AF1, SRI, MFF, PPM1G, CDC42, MIEN1, U2AF2, TIFA, PCBD1, SH2B1, SLC12A2, GADD45GIP1, TRIM41, MID1IP1, HIP1R, IMMT, RPL23A, HNRNPAB, REC8, CTCFL, MYO1D, CD24A, TSPAN13, SYT11, EIF3L, EIF3G, PDCD4, P4HB, EIF3F, KCNK1, TBATA, BCAR1, EIF3A, EIF4A1, SMARCB1, AHCYL1, PLEKHB1, KEAP1, GCC2, ACTB, NUBP1, CRKL, UBE2L3, CCAR1, LGALS4, TRIM28, CHORDC1, RASSF6, CCNL2, TRIM27, CCNL1, ATP6V1E1, EPHB4, TMPO, SMARCC1, ATP6V1G1, SMARCC2, ACTN1, CSNK1D, ACTN4, FNDC5, CSNK2B, ULK1, KCTD12, GRB7, GGNBP2, DHX9, MYCBP2, CTR9, PIK3R1, SNX3, APH1A, SEP15, ATP5B, SNX1, PCBP1, MICAL1, PCBP2, DHX36, SWI5, N4BP1, CTSA, SURF4, SMARCA5, RAB27A, RAB27B, SMARCA2, NET1, MC1R, SNW1, WNK1, ID1, ID3, CALR, RAB9, PPP1R10, MRPS14, PAK1IP1, WASL, AP2A2, HERPUD1, PPP3CA, MAP1LC3B, PCLO, SPTLC1, CTSL, HNF4A, MLX, IDS, KIF1B, RAC1, GIT1, CCT3, SREBF1, PBRM1, DBNL, CACYBP, COMMD1, SYN2, CTTN, CANX, KIT, UFC1, TAX1BP1, PABPC1, CD47, MICU2, CD44, DBN1, NAPA, CD63, PCNA, NLRP1A, STX16, DERL1, GNAI3, PRICKLE2, NEDD8, GNAI2, PAK1, SAMM50, PGRMC2, RXRA, SERTAD1, OS9, TCEB2, TCEB1, CCT8, CCT7, PAK2, XDH, CCT5, CCT4, BCAP31, CD74, NPM1, MAP3K1, SORT1, TMEM176B, TMEM176A, RPA2, HYPK, PPP1CA, VEGFA, FKBP1A, SGSM3, NEDD4, TCEA1, HDGF, TARDBP, PNPLA2, TXN1, CD81, ZFAND6, INPPL1, NR3C1, TTF1, ETS1, IGF1R, EEF1B2, RGS2, CCND2, CCND1, DMBT1, PLAU, KIF5B, EP300, CAR8, CAPN1, SH3GL1, FBXW11, CASK, UBE4B, CYBA, WBP11, PRLR, EEF1A1, ERN2, HNRNPUL2, TMEM259, DKC1, UBE2V2, PPIF, GEMIN7, UBE2V1, PPIA, RTN3, DDX5, VCP, TSG101, PSMD14, ARHGEF28, DDX1, SEL1L, TOR1AIP2, CACNA1A, PSEN1, CACNA1H, RTN4, CNN3, IRAK1, TBC1D13, PACSIN2, LLPH, CYC1, NDUFV1, WNT3, IVNS1ABP, PRNP, UBE2I, UBE2B, VDR, GNAO1, IFT20, VIL1, UBE2W, HOOK2, NASP, CCPG1, GNAQ, GNB2, TRP53, BHLHE40, GNAS, UBE2N, UBA2, UBA1, TCF3, GALK1, YWHAE, LGALS3BP, RERE, GSK3B, GSK3A, LDB1, PRKCSH, YWHAB, CHD7, ATP2A3, ATP2A2, ADAR, CHD4, CHD3, AFF4, GHR, LASP1, YWHAQ, RB1CC1, NUP62, UQCRFS1, YWHAG, YWHAH, MKL2, TGIF1, RBM17, GLRX3, EED, YWHAZ, PJA2, TAPBP, ETV6, CCNA2, SFPQ, PEX6, NUP50, IRF1, IRF7, VIMP, PLEC, RBM47, RALA, DDX21, RNF6, SLC3A2, RRBP1, ATP2C2, RNF4, RNF5, PDLIM1, CLN3, CAND1, PABPN1, TRA2B, MKNK2, PTK2B, PDLIM5, ATOH1, TTC14, RBM39, RRM1, NAA10, BNIP3, CCK, ATP2B1, MAPK14, H2-AA, SOD1, PNKD, TEF, ERCC4, CD9, KRAS, VIM, RAN, TAF1, RPL4, RPL5, RPL31, SERPINE1, HNRNPU, RPL8, SMC3, SLC4A4, BACH1, PHB2, GLS, MILR1, ALCAM, TFG, MYC, STMN1, MYB, AP1S1, VPS35, JUNB, MS4A10, RPL39, CDK5RAP3, CHGB, PRKCI, RPL21, PIH1D1, PRKCA, HCFC1, SYTL2, RNF126, SARNP, CLPP, MAP1B, PARD3, MAP1A, H2-D1, VPS28, CTBP2, CTBP1, HSPA4L, NOLC1, PRKCZ, HIF1A, PLAC8, PRDX2, BLOC1S1, RAD21, PRDM16, GAR1, NKX2-2, NAA50, JUND, HOMER2, PLK1, NFATC3, CGN, HNRNPL, EHD1, GLUD1, HNRNPK, ARL2BP, PPT1, TPRGL, CEP57, CDKN1A, BTG2, CDKN1B, BTG1, ARPC1A, SETD7, CLTC, ASH2L, STON2, TRIM8, CSRP2, AIFM1, CSRP1, TMSB4X, TRIM2, RFK, JARID2, NUDC, ANXA2, ANXA5, ATPIF1, PAX6, GNL3, AES, BACE1, NCOR1, TCP1, GARS, PLIN2, SF3B2, NR1I3, GPS1, RPL12, USO1, RPL11, NR1I2, BCLAF1, NDNL2, NSD1, RPS3, CKB, LDLR, RPL17, SF3B1, RUNX1T1, CCL25, GSN, ELP2, WWP2, HIPK1, ERP44, PHF5A, RNF149, RFWD2, ABI1, ZYX, ANKS4B, LAMTOR2, LAMTOR1, LAMTOR3, RAB3B, FAM49B, RAB3C, RAB3D, CTNND1, YEATS4, PARK7, FGF1, SLC8A1, IPO5, PPP1CB, PYCARD, PPP1CC, ZFP36, DACH1, LAMP1, CDH1, PLS1, GTF2I, HMGN1, TPD52, MAP2K3, TOR3A, USP7, MAP2K2, TPM3, RPS6, THOC3, GTF2F2, THOC7, NRBP1, CTDNEP1, MORF4L1, STIM2, NCL, NHP2, MALAT1, ADNP, SNRPB, DNMT1, CBFB, INSIG1, CUL3, ITPR1, UBR3, ITPR3, KLC1, GTF2E2, BAG6, NEUROD1, STIP1, TPR, DVL1, BTBD2, BAG1, ABL2, RAB6A, MCL1, CD164, RAB4A, CHTOP, ANKRD27, TRAPPC4, SHFM1, TOR1B, HOPX, LSM2, COPS4, CDK9, LSM7, COPS5, DAB1, REEP5, CDK4, CNOT1, BCL3, CDK1, PLXNB2, TPP1, REEP6, RAB5A, SLC26A3, EIF4G2, BCL2L2, MAP3K11, EIF4G1, MCM7, DUSP16, RPL7A, PTBP1, AP1G2, SIN3B, AP1G1, UBTF, EFHD2, PRKG2, EIF2B1, SKP1A, TNPO2, PDCD6IP, GPX1, DNMT3A, COBL, APOA1, TSN, NIPSNAP1, DUSP22, DNAJC2, PKM, ASPH, DNAJC5, POLR1D, RP9, MCM6, CRK, SSX2IP, CEBPA, WBP1, HDAC1, WBP2, CEBPG, HECTD1, TTR, RAB25, RBBP4, DNAJB6, POLR2C, RAB24, SNRPB2, CSK, BAK1, RBBP7, UGGT1, POLR2J, SMARCE1, RNF20, TRPA1, AMFR, SEMA4B, SEMA4G, KLF4, RAB10, DNAJA1, NFASC, KLF5, VAPA, RAB14, APC, RAB15, RPS3A1, CTH, DNAJA3, VPS41, INSM1, RAB17, METAP2, APP, ARL6IP1, GOLGA2, RPS15, PPP2R1A, DAG1, ARL6IP4, SOX9, GLUL, B2M, SLC6A19, KRT8, AP1B1, ACSL6, KRT7, SLC51A, JMJD6, AKAP9, XRN2, VDAC1, PFN1, EZR, ZFPM1, CFTR, IGSF8, IGSF5, BEX1, ANP32A, MAGED1, MAOA, TSHZ1, STXBP1, STXBP2, MTTP, PDCD10, MAP7, RALGDS, SPTBN1, VASP, H2-EB1, GADD45A, PUM2, GADD45G, CCT6A, OCLN, FUBP1, ITM2B, DAZAP2, ZCCHC11, CITED2, FAF1, ZFAND2B, LIMD1, KRT20, PRPF19, SPPL3, GYS1, FTL1, XPO1, SH3PXD2A, CHMP1A, RAB8A, PSENEN, PRMT5, PARP1, PRMT1, RHOG, GFRA3, RHOC, CBFA2T3, ITFG1, RHOA, MLF2, RAB33B, CEACAM1, STRAP, MAPRE1, AKAP7, PTS, PPP2CA, PURB, LIMA1, PPP2CB, CHRAC1, CXCR2, LMNA, CTNNA1, MPP1, CDX2, SLC31A1, RYK, MPP5, RAB11A, RAB11B, RSL1D1, KRT19, KRT18, CAPZA1, CAPZA2, CTNNB1, FAU, TJP3, TJP2, FCGBP, KDM1A, MRFAP1, CIB1, ESPN, TOMM22, CHCHD3, ARHGDIA, COTL1, PDIA3, PHYH, RALBP1, APLP2, APLP1, WRNIP1, ATP1B3, ATP1B1, CHMP4B, NUPR1, PXN, FBLN1, LPP, FBLN2, ZFP36L1, SDCBP, UBC, EP400, STAP2, HSPA9, HSPA8, CBX5, HSPA5, CBX3, HSPA4, NONO, DNAJC15, EIF2S2, SMAD5, EIF2S1, DLG1, JMY, DNAJC10, CHMP2A, DYNLRB1, FGFR3, KDM5A, B4GALT1, ABCD3, PYCRL, THRA, USP33, DOCK7, SLC2A1, SLC40A1, YBX1, UBE2D2A, YBX3, ELAVL1, CASP6, MCF2L, CASP1, BLNK, CASP2, HIST1H1C, ABCC2, DCXR, H2AFX, AXIN2, ARID1A, SAFB, DNM1, TGFBR1, DNM2, RABEP1, THRAP3, MYH9, CDH17, CAMK2B, TSEN34, KDM3A, POMP, ATP1A1, UACA, DLL1, THBS1, TOB1, MUC2, PRRG2, ERBB2, MAPK1, HES1, MAPK3, IGBP1, TCF7L2, TMEM30A, WTAP, BAD, PDE4DIP, NAP1L1, MLPH, TOMM70A, SPRY2, BAX, LTBR, SSBP2, SSBP3",3206,4092,17446,1.391004098,1.15E-36,3.84E-37,3.68E-37
GOTERM_MF_DIRECT,GO:0003735~structural constituent of ribosome,137,3.683785964,1.28E-34,"RPL4, RPL5, RPL3, RPL32, RPL31, RPL34, RPL8, RPL10A, RPL9, RPL6, RPL7, RPS15, RPS14, RPS17, RPS16, RPL18A, RPS19, RPS18, RPL36AL, RPL36, RPL35, RPL38, RPL37, RPS11, SLC25A45, RPS10, SLC25A44, RPL39, RPS13, RPS12, RPS9, RPS7, RPL21, RPS8, RPS5, RPL23, RPS6, RPL22, MRPS18B, RPSA, RPL24, SLC25A51, RPL27, RPL29, UBA52, RPL28, MRPL18, MRPL19, MRPL14, MRPL15, MRPL12, MRPL13, MRPL10, MRPL11, MRPL20, GM6525, RPL41, MRPL27, MRPL28, MRPL23, MRPL24, MRPL30, RPS26, RPS25, RPS28, RPS29, RPL27A, RPS20, RPS21, RPS24, RPS23, SLC25A1, MRPS17, MRPS15, SLC25A3, MRPS16, MRPS14, RPLP1, RPLP0, MRPS12, MRPL36, MRPL37, MRPL34, MRPL33, MRPL4, RPS4X, MRPL3, MRPL2, MRPL1, RPLP2, MRPL9, MRPS24, MRPS23, GM10653, RPL13A, MRPS21, MRPS7, MRPL43, MRPS5, MRPL52, SLC25A15, MRPS9, MRPL51, GM4832, RPL37A, SLC25A10, SLC25A5, SLC25A11, SLC25A4, RPL10, RPL12, MRPS34, RPL11, RPL36A, MRPS31, RPS27L, RPS15A, SLC25A28, UCP2, RPL14, RPS3, RPL13, RPS2, RPL15, RPL18, RPS27A, RPL17, RPL19, NDUFA7, RPL35A, RPL23A, RPL34-PS1, SLC25A39, RPS3A1, RPL22L1, FAU, SLC25A35",3206,264,17446,2.8238979,2.83E-31,6.56E-32,6.29E-32
GOTERM_MF_DIRECT,GO:0003723~RNA binding,285,7.663350363,1.48E-34,"EIF4A2, EIF4A1, RPL5, AHCYL1, RPL34, HNRNPU, RPL8, EPRS, RPL9, RPL7, NUDT4, RPS15, TIAL1, RPS14, RPS16, RPS18, SNRPD1, MAGOH, RPL38, RPL37, SNRPD3, RPS11, RPL39, DDX17, MBNL1, MBNL2, IMP3, RPL22, CIRBP, IMP4, MIF4GD, RC3H2, SRRM1, JMJD6, MARF1, DDX39B, EWSR1, TEP1, EIF1A, SF1, SLBP, GRB7, DHX9, MRPL18, BAZ2A, RRP7A, LARP1, PCBP1, PCBP2, DHX36, GAR1, N4BP1, ZRSR1, MCTS1, PNO1, SETD1B, PA2G4, PUM1, LARP4, MRPL23, PUM2, HNRNPL, AIMP1, MOV10, HNRNPM, RPS28, HNRNPK, QARS, FUBP1, HNRNPF, HNRNPD, RPS20, RNPS1, HNRNPC, NOL12, FARSB, MRPS17, DAZAP1, PPP1R10, SYNCRIP, XPO1, NELFE, CLUH, STRBP, NSUN2, ZFR, NUDT16L1, MRPS5, SRP9, PSMA6, SLTM, NHP2L1, HNRNPH1, CSDE1, FRG1, HNRNPH2, PABPC1, SF3B4, RNASEL, SF3B3, NIP7, RPL12, RPL11, PURB, EXOSC7, SCAF8, EXOSC5, RPS3, RPL13, RPS2, RPL18, SRSF10, SF3A3, YTHDF1, NPM1, SF3A1, TRMT1, SRP68, RPL34-PS1, LRPPRC, TARBP2, RSL1D1, MARS, HNRNPA2B1, SERBP1, TARDBP, HDLBP, MSI2, PARK7, SRP14, RPL10A, YY1, FBL, KHSRP, PAPOLA, NUDT16, RPS9, EIF1AX, RPS5, THOC3, LARP4B, THOC7, ILF3, RBMXL1, DKC1, NCL, NHP2, SRSF2, SNRPG, SRSF3, SNRPE, MATR3, SNRPF, SRSF5, 2810403A07RIK, SNRPC, SRSF6, SRSF7, SNRPA, SNRPB, SRSF9, ANKRD17, KHDRBS1, DDX6, DNMT1, DDX5, RNASEH2A, YTHDC1, ARHGEF28, DDX1, IREB2, TARS, PRPF8, ZFP36L2, HSP90B1, EMG1, ZMAT2, G3BP1, SAFB2, G3BP2, BRIX1, HSPA8, CBX7, CPSF7, TIA1, CHTOP, CPSF6, CPSF1, ALYREF, CPSF3, NONO, FAM103A1, LSM1, CWC15, EEF2, LSM4, EIF2S1, LSM2, CHERP, ISG20, CNOT4, LSM7, SON, LSM6, CAPRIN1, SKIV2L, ACO1, EIF4G2, EIF4G1, RBM25, DDX3X, DDX46, PRKCSH, CELF1, CELF3, HMGB3, ADAR, YBX1, YBX3, ELAVL1, MRPL4, RPS4X, RBM3, DUSP11, RPL7A, PTBP1, MRPL2, MRPL1, SNRNP70, RBM34, EIF5A, RBM17, RBM14, NCBP2, GM10653, DDX54, SAFB, TSN, PTBP3, SFPQ, ESRP1, SNRPA1, ANG, EIF4E2, SKIV2L2, RBM47, DDX24, SRSF1, DDX21, U2AF1, SAMHD1, PUF60, PABPN1, U2AF2, TRA2B, FAM120A, TRA2A, EIF4H, POLR2G, SNRPB2, IGF2BP2, RBBP7, EIF4B, HNRNPA0, SMARCE1, PTCD3, RBM39, HNRNPA3, SSB, RPL23A, HNRNPAB, U2SURP, TNRC6C, 2700060E02RIK, EIF3K, IMPDH2, EIF3G, PDCD4, SLIRP, EIF3C, EIF3D, EIF3A, TNRC6A, EIF3B, TNRC6B",3206,780,17446,1.988303182,3.28E-31,6.56E-32,6.29E-32
GOTERM_MF_DIRECT,GO:0000166~nucleotide binding,551,14.8158107,4.03E-31,"DQX1, TESK1, ARAF, HNRNPU, HNRNPR, SMC3, EPRS, SMC4, MYLK, AKT1, PIP4K2C, PRKACA, PRKACB, DDX17, PRKCI, PRKCD, PRKCA, AARSD1, GTPBP1, GTPBP4, LARS2, DDX39B, MTHFD1, TEP1, PRKAR1A, EWSR1, IDNK, PI4K2A, GNE, SAR1A, HSPA4L, AGAP1, ABCB9, PRKCZ, RRP7A, PRKAR2A, MYO6, PIP5K1B, CDK18, CHKB, CHKA, SETD1B, PLK1, UPF3B, LARP4, MRPL23, HNRNPL, EHD1, MOV10, HNRNPM, GLUD1, EIF5, HNRNPF, HNRNPD, HYOU1, HNRNPC, FARSA, ITPA, FARSB, ARF3, ARF4, MOCS2, SMG1, ARF1, SRPR, ADK, PRKAG1, PRKAG2, AACS, TUBA1C, TUBA1B, TUBA1A, RARS, RFK, PBK, TK1, JAK1, NELFE, SPHK2, ITPK1, BAZ1B, GNL3, GM4832, DPYD, TCP1, GARS, GART, ARF5, RAPGEF4, ARF6, SF3B4, RNASEL, ATP5A1, SRRT, ADCY1, ADCY6, EGFR, PAPSS2, PAPSS1, SCAF8, ASNA1, CKB, ABCB1A, SRSF10, SRSF11, PKLR, RIOK3, CSNK1A1, GSS, TUBB4B, HIPK1, PSMC5, PSMC6, TAOK3, PSMC3, PSMC4, ETNK1, PSMC1, PKN2, FRK, RAB3B, RAB3C, RAB3D, UBE2D3, MSI2, RAB43, SLK, TUBB5, RUVBL2, STK16, PAPOLA, PIM3, PIM2, NUDT16, RAB2A, MAP2K3, TOR3A, MAP2K2, SARS, LARP4B, GTF2F2, DGKZ, TUBA4A, APOA1BP, NAIP2, ACLY, NAIP5, RBMXL1, NCL, MAPKAPK2, SRSF2, SRSF3, SRSF5, SNRNP200, SRSF6, SRSF7, SLC27A2, SNRPA, NAIP1, SRSF9, ARL8B, SLC27A4, PFKFB4, ARL3, AK2, TARS, AK3, AK4, HSP90B1, RAP1B, RAP1A, STK38, G3BP1, PMVK, G3BP2, SAFB2, ABL2, EIF2S3X, IP6K1, RAB6A, NADK, TIA1, RAB4A, RAB4B, ATP8B1, FUS, ASNS, HPRT, TOR1B, EEF2, CNOT4, CDK9, CDK8, GNL3L, STK24, CDK4, CDK1, IARS, RAB5A, MAP3K11, HSP90AB1, MCM7, SRXN1, CELF1, CELF3, PIK3C2A, PTBP1, SNRNP70, PRKG2, ARL5A, ACTR3, ACTR2, EIF5B, HSP90AA1, RFC1, ATRX, PTBP3, ARL4A, PKM, ESRP1, PCCB, MCM3, PIK3C3, MCM5, MCM6, DCTPP1, MCM2, PRPS2, ACSS2, ROCK1, SRC, ROCK2, RAB1B, SRSF1, U2AF1, CDC42, CKMT1, PUF60, RAB25, U2AF2, RAB24, EIF4H, SNRPB2, CSK, IGF2BP2, ACSS1, ADSS, ATP9A, EIF4B, HNRNPA0, HNRNPA3, SSB, MYO10, IDH3G, AMFR, RPL23A, HNRNPAB, TNRC6C, MYO1D, BCKDK, RAB10, SNRK, PFKL, MYO1B, SUCLA2, RAB14, IMPDH1, MYO1A, RAB15, IMPDH2, EIF3G, RAB17, PFKP, TNRC6A, EIF3B, TNRC6B, EIF4A2, EIF4A1, PANK3, VARS, MKI67, ACTB, NUBP1, UBE2L3, RPS6KA4, TIAL1, RPS6KA1, LONP1, PDK3, KIF21A, SEPHS2, GLUL, PDK2, EPHB4, EPHB3, CIRBP, MYO7B, ACSL6, ACSL5, CSNK1D, ACSL3, MARF1, CDC34, KARS, RRAGD, VDAC3, SUCLG2, VDAC2, SUCLG1, ULK1, VDAC1, CFTR, TMEM63A, DHX9, GSPT1, ATP5B, DHX32, RRAS, HLTF, DHX36, TRPM4, PCK2, ZRSR1, TRAP1, SMARCA5, RAB27A, RAB27B, PAICS, SMARCA2, CCT6A, ICK, WNK1, MYO5B, RNPS1, ALDH18A1, RPS24, DDR1, RAB9, TOP2A, DAZAP1, OLA1, KIF11, KHK, SYNCRIP, ACTR1A, HINT1, HINT2, GUK1, REV3L, DHX15, KIF1B, RAC1, RAB8A, CCT3, CCT2, WARS, PABPC4, MINK1, NME2, RHOG, KIF24, SYN3, RHOC, RHOA, NME1, RAB33B, SLTM, HNRNPH1, KIT, FAM20B, HNRNPH2, RHOU, PABPC1, TOR4A, GUCY2C, DTYMK, NLRP1A, GNAI3, AKAP7, GNAI2, NT5C, PAK1, CCT8, PAK3, CCT7, PAK2, CCT5, CCT4, MAP4K4, DYNC1H1, MAP3K1, GCH1, RYK, UBE2G1, RAB11A, RAB11B, MARS, STK17B, HNRNPA2B1, HDGF, TARDBP, GIMAP1, PEBP1, ACTG1, IGF1R, NARS, KIF5B, ABCG5, LIG1, CASK, WRNIP1, ATAD3A, TUFM, EEF1A1, ERN2, CMPK1, MATR3, ATP6V1A, RASL12, DDX6, VCP, DDX5, PKDCC, RBM8A, UBA5, DDX1, NLRP6, IRAK1, GRK4, EP400, MYH14, MARK2, HSPA9, HSPA8, CPSF7, CPSF6, UBE2I, HSPA5, UBE2B, UBE2C, HSPA4, ALYREF, NONO, TIMM44, CLK2, GNAO1, CLK1, UBE2W, GCLC, CPS1, UBE2S, GNAQ, GNAS, UBE2N, SRPRB, UBA2, UBA1, UBE2K, FGFR3, GALK2, GALK1, UBE2M, ABCD4, GSK3B, GSK3A, RBM25, ABCD3, DDX3X, DDX46, MAST3, CHD8, MAST2, CHD7, ATP2A3, ATP2A2, CHD4, UBE2D2A, ELAVL1, HK2, RBM3, GMPPB, SEPT9, UBE2Q1, MYO18A, RBM34, ABCC3, RBM17, RBM14, CAMK1D, ATP6AP1, NCBP2, CAD, HUNK, DDX54, SAFB, DNM1, TGFBR1, DNM2, SFPQ, UBE2R2, THRAP3, PEX6, HKDC1, MYH9, PDE5A, MVD, SKIV2L2, CAMK2B, PDXK, RBM47, RALA, MVK, DDX27, DDX24, TUBAL3, DDX21, ATP2C2, ATP1A1, CLCN3, NT5C3, HSPD1, GNA13, MAT2A, PABPN1, GNA11, POLD1, TRA2B, ERBB2, TRA2A, MKNK2, PTK2B, MAPK1, MAPK4, ABCF1, MAPK3, DDX39, RBM39, RRM1, ATP13A1, LIMK2, ATP2B1, MAPK14, CDK11B, U2SURP, MAPK13, ACIN1, KRAS, ATP13A3, SLIRP, RAN, TAF1",3206,1936,17446,1.548740288,8.93E-28,1.49E-28,1.43E-28
GOTERM_MF_DIRECT,GO:0019899~enzyme binding,143,3.845119656,1.76E-18,"TXN1, APP, KDM1A, PEBP1, SLC4A2, PARK7, MYLK, PYCARD, GCSH, ZFP36, LAMP1, CCND1, LAMP2, COTL1, HIST1H2AE, AKT1, BANF1, SNRPD3, LGALS9, ATG3, HIST1H2AO, TSPYL1, PRKCD, PRKCA, UBE4B, TUBA4A, POR, ILF3, TEP1, FDX1, SLC27A2, KPNB1, CFTR, PPID, CUTA, DDX5, PHB, OAZ1, HIF1A, ACAT1, PCBP2, DVL1, MLEC, GSTM4, HSPA9, HSPA8, GSTM2, JUN, ZFHX3, JUND, UBE2I, CPSF1, HSPA5, CBX3, EPHX1, GOT2, DHCR24, TIMM44, ARPC4, MARCH6, IGF2R, GLUD1, TRP53, NOXA1, ALB, GSTM7, YWHAE, TOP2A, BTG1, LDB1, YWHAB, PTEN, ATP2A2, POLB, PPP3CA, RAC1, SLC18A1, SLC18A2, YWHAH, PARP1, H2AFY, PRMT1, CAD, ATP6AP2, H2AFX, NME2, APOA1, AXIN2, DYNLL1, NME1, BACE1, GCHFR, PLSCR1, NPC2, EHHADH, CAT, PEX5, PICK1, BIRC5, TMBIM6, GAPDH, CRK, SLC25A4, LUC7L2, VIMP, MCM2, DDC, PCNA, NLRP1A, SRC, HDAC1, NOXO1, MAT2B, EGFR, PPP2CA, RXRA, TNKS2, U2AF2, POLD1, RPS3, PTK2B, RPS2, EGLN1, NPM1, SORT1, TAF10, PTGES3, USP22, RPA2, PDE4DIP, MAPK14, SOD2, TARBP2, SOD1, FKBP1A, TSPAN15, GOLPH3, EIF3I, CTNNB1, PDCD2, P4HB, ATXN10, APBA3",3206,384,17446,2.026455929,3.90E-15,5.57E-16,5.34E-16
GOTERM_MF_DIRECT,GO:0016491~oxidoreductase activity,196,5.270233934,2.43E-17,"CYP3A11, CYP3A13, IFI30, ALKBH5, FTH1, ACAD11, MECR, JMJD6, POR, MTHFD1, MTHFD2, ETHE1, AKR1C13, HPD, TSTA3, TPH1, MAOB, CTBP2, RETSAT, CTBP1, MAOA, AKR1C19, ADH5, PRDX3, PRDX2, ADH4, CYB5R1, ADH1, PRDX5, LDHA, PRDX4, CYB5R3, PRDX1, MICAL1, MARC2, DECR2, FDFT1, VAT1, OSGIN1, MICAL2, PYCR2, CYP3A25, ACADSB, PRDX6, MSRA, GLUD1, ADI1, FASN, CYP2S1, OGDH, ALDH18A1, PAM, DHRS11, GDI1, HIBADH, TECR, GDI2, RDH7, AKR1B7, ACADL, AIFM1, CYP2B10, 4833439L19RIK, SCD2, QSOX1, PHGDH, ACADM, SCD1, ACADS, VKORC1, CBR1, GSTO1, AKR1A1, PTGR1, UGDH, HADHA, BDH1, DPYD, DLD, PCYOX1, HSD17B4, FAM213B, CYP2C55, CREG1, SC5D, 4933434E20RIK, XDH, EGLN1, NQO1, EGLN3, MDH1, MDH2, GSR, DHRS1, FMO5, DHRS3, DHRS4, DHRS7, CYP2C66, CYP2C65, MSRB1, KDM1A, CPOX, PLOD3, H2-KE6, ERO1L, TM7SF2, AKR7A5, HADH, FADS1, PHYH, KDM2A, CYBA, PGD, SDHA, SDHB, CYP2D26, ALDH3A2, GPD2, GPD1, GLYR1, ALDH3B1, NDUFV2, NDUFV1, PDHA1, CYP2J6, SRD5A1, IDH1, IDH2, DHCR24, CYP2C29, CYP51, CYP4F14, QDPR, GRHPR, DNAJC10, CRYL1, DEGS1, DHCR7, DEGS2, KDM5A, ACADVL, PYCRL, SRXN1, ETFA, SQRDL, SPR, HEPH, ALDH2, CYP4V3, UQCRFS1, ME2, IDH3A, KDM6B, GPX2, GPX1, ADH6A, GPX4, GPX3, DCXR, SORD, NDUFS8, NDUFS7, ASPH, ACOX1, EHHADH, G6PDX, CAT, ALDH1A1, NDUFS3, NDUFS2, NDUFS1, ALDH1A7, ALDH9A1, KDM3A, SEPW1, HSD17B13, HMGCR, HSD17B11, HSD17B10, ALDH1B1, BCO2, HSD3B7, RRM1, IDH3G, SMOX, TXNRD1, CYP4B1, SOD2, SUOX, GFER, SOD1, IMPDH1, IMPDH2, ALDH16A1, CDO1",3206,604,17446,1.765840539,5.39E-14,6.74E-15,6.46E-15
GOTERM_MF_DIRECT,GO:0032403~protein complex binding,131,3.522452272,3.65E-16,"PPP2R2A, NR3C1, TXN2, GOLGA2, PPP1CC, TUBB5, RPS19, CCND1, MYC, EP300, PRKACA, CDK5RAP3, PDK2, STX7, KRT8, CASK, MIF, ACTN4, RBX1, DDX39B, MAP1B, UQCRC1, VDAC1, MALAT1, ULK1, UQCRC2, EZR, PPIB, ATP6V0D1, KPNB1, VPS28, PI4K2A, KHDRBS1, VCP, TMED10, PXN, ITPR1, TWF1, FBLN1, IQGAP1, ATP5O, HIF1A, UQCRH, RTN4, RAP1B, SLC9A3R1, RAP1A, RRAS, KCNQ1OT1, ATP5D, SPTBN1, HSPA4, ST13, GNAO1, CPS1, ARPC2, CDK4, CPD, GNAQ, GNB2, GNB1, RPS24, ITGB1, YWHAE, UFD1L, CDKN1A, SLC25A3, CDKN1B, THRA, YWHAB, ARPC1B, BRK1, KIF11, MYSM1, AP2A2, PTPRF, FLCN, SIPA1L1, CTSL, ANXA6, UQCRFS1, GIT1, CTSB, SREBF1, PRMT5, YWHAZ, TGFBR1, TSN, DNM1, DNM2, TNFRSF1A, HADHB, HADHA, PEX6, TOP1, PPARA, PAFAH1B1, RAPGEF4, CEBPA, DYNC1I2, CD63, SRC, HDAC1, STRN4, HSPD1, PPP2CA, RXRA, EPCAM, GNA11, PTK2B, TCEB2, TCEB1, HES1, RPS2, MUC4, NDUFA9, IGBP1, BCAP31, NDUFA8, NDUFA4, CRIPT, PPP1CA, KRT19, APC, RPS3A1, ABI1, CTNNB1, BAX, KRAS, PFKP, RAN",3206,358,17446,1.991226297,7.38E-13,8.98E-14,8.61E-14
GOTERM_MF_DIRECT,GO:0019904~protein domain specific binding,111,2.984673299,1.86E-15,"FOXA1, CTNND1, PPP1CC, TUBB5, LAMP1, CDH1, LAMP2, TGM2, PRKCI, ACTN1, ACSL3, SCAMP1, CSNK2B, EZR, KPNB1, DDX6, DNMT1, VCP, CTBP1, STXBP1, PIK3R1, IQGAP1, PRKCZ, SLC9A3R1, PRKAR2A, RAB6A, WNT3, HSPA5, CBX3, HOMER2, ST13, RCC2, RAB27A, RAB27B, HNRNPM, OCLN, HNRNPK, CNOT1, CHMP2B, BHLHE40, CHMP2A, GNAS, ID3, CPE, CALM3, HNRNPC, CALM1, CALM2, OGT, NFE2L2, ITGB1, YWHAE, SNAP25, THRA, YWHAB, FAF1, ICA1, HMGB2, TNFAIP1, MAP1LC3B, TUBA1A, XPO1, YWHAQ, CHMP1B, CHMP1A, CASP2, YWHAG, YWHAH, DLGAP4, DBNL, ABCC2, RFC1, ITGA3, DYNLL1, YWHAZ, RHOA, ETV6, HAX1, NCOR1, PICK1, MYH9, HAP1, PPARA, SSX2IP, CRK, CEBPA, DDC, SRC, GNAI3, MRPS31, AKAP7, ATP1A1, STRN4, PPP2CA, PPP1R2, SCAF8, RXRA, UBQLN1, IGBP1, PCGF6, GSN, MBD2, MPP5, MYO1D, NFASC, VAPA, FOXA3, BCAR1, RAN, FOXA2, TJP2",3206,289,17446,2.0900539,4.18E-12,4.12E-13,3.95E-13
GOTERM_MF_DIRECT,GO:0042802~identical protein binding,190,5.108900242,1.64E-13,"APP, CDA, TFRC, PDCD6, CPOX, GCC2, PARK7, CLDN2, ETS1, ACTB, IGF1R, ACTG1, PYCARD, SLK, TFG, RASSF3, PSMD4, RUVBL2, AKT1, TRIM27, PIP4K2C, NUDT16, REG1, GLUL, B2M, SH3GL1, SH3GLB1, BNIP3L, CPT1A, IK, S100A1, APLP2, APLP1, WRNIP1, POU3F2, JMJD6, HCFC1, CLDN4, CLDN3, DDX39B, NCL, CLPP, CLDN7, CSNK2B, FKBP8, CHMP4B, SNRNP200, ATF6, SQSTM1, ATF3, OPTN, REG3B, GRB7, KHDRBS1, VCP, SHMT2, BRI3, STXBP1, SHMT1, LYZ1, MGST1, AK3, FBLN1, UAP1, ADIPOR2, CORO1B, DPP4, PRDX3, SDCBP, SNX1, PRRC1, DVL1, SAFB2, PACSIN2, PRNP, JUN, CBX3, ST13, NONO, GOT2, HPRT, PAICS, NFKB1, IGF2R, VIL1, HOOK2, FASN, TRP53, ALB, SELK, HNRNPC, ALDH18A1, DYNLRB1, MAP3K11, TPRGL, PICALM, CEP57, MOCS2, PYCRL, PTEN, SLC2A1, FHL2, DPY30, PRPF19, PTPRG, ALAD, TRIM8, FTL1, ALDH2, IMPA1, CASP6, CHMP1A, ACADM, TK1, HSP90AA1, PARP1, EED, PRMT1, ANXA4, CAD, DNMT3A, SORD, APOA1, COMMD1, RGMB, YWHAZ, DNM1, MTSS1, NME1, TRAF4, CLDN15, G6PDX, ALDH1A1, PICK1, BIRC5, ALDOB, MCM6, LCP1, MAPRE1, FBP1, PAFAH1B3, GAPDH, DCTPP1, PRPS2, USP15, OAT, AHCY, PCNA, MVK, UHRF1, PON2, NOXO1, RNF4, HSD17B10, PSMA7, EGFR, PTS, CST3, LMAN1, TTR, UGP2, PUF60, ERBB2, UBQLN1, MAPK1, STAT6, PCBD1, CSK, FLNB, BAK1, RABAC1, CCT7, PAK2, LDLR, BCHE, NQO1, BNIP3, STAT3, SOD2, VEGFA, SOD1, 2700060E02RIK, PFKL, TRIM39, VPS41, BAX, VIM, LTBR, ATXN10, TARDBP",3206,625,17446,1.654268247,3.63E-10,3.30E-11,3.17E-11
GOTERM_MF_DIRECT,GO:0019901~protein kinase binding,142,3.818230707,6.47E-13,"ATF2, CTNND1, PEBP1, CIB1, ACTB, GOLGA2, PPP1CB, LIPE, ZFP36, CCND2, RPS19, CCND1, RPS18, PPME1, DPYSL2, ARHGDIA, EP300, AKT1, CCNL2, PRKACA, CCNL1, SLC12A7, CDK5RAP3, MAP2K3, PIH1D1, PRKCD, RPS6, AP1B1, ACSL3, TICAM1, PRLR, EEF1A1, CDC37, JTB, VDAC1, ULK1, UTRN, SQSTM1, PFKFB2, GRB7, STXBP1, PXN, GATA6, PIK3R1, IQGAP1, ZBTB4, PRKCZ, HIF1A, FAM83H, PRDX3, FAM83E, PDCD10, DVL1, TRAP1, GSTM1, JUP, RCC2, PLK1, EEF2, LSM2, CDK9, MLXIPL, IBTK, DLG1, RGCC, QARS, WNK1, TRP53, PAM, ITGB1, GSK3B, GSK3A, B4GALT1, HSP90AB1, FAF1, CLTC, PTEN, PRKAG1, PRKAG2, PTPRK, KIF11, ELAVL1, AP2A2, CKS1B, GHR, GYS1, SIPA1L1, RB1CC1, RAC1, RAB8A, SREBF1, HSP90AA1, PARP1, H2AFY, PGAM1, PAX6, AXIN2, YWHAZ, ADRA2A, DNM1, DNM2, NME1, DNAJC3, CCNA2, CEACAM1, TRAF4, CKS2, CD44, CAMK2B, PPP1R15A, STX17, SRC, GSTP1, MVP, AKAP7, ATP1A1, EGFR, ADCY6, PPP2CA, CDC42, PAK1, CAMK2N1, RPS3, MAPK1, PAK2, MAPK4, HNRNPA0, SLC12A2, TCF7L2, NPM1, MAP3K1, KIDINS220, BAD, STAT3, TPRKB, ELP2, CD24A, APC, SPRY2, CTNNB1, VIM, BCAR1",3206,434,17446,1.78045485,1.43E-09,1.19E-10,1.14E-10
GOTERM_MF_DIRECT,GO:0003729~mRNA binding,64,1.720892713,7.66E-13,"RPL5, RBM25, CELF1, EIF4A3, YBX1, PARK7, ELAVL1, RPL6, RPL7, PTBP1, ZFP36, SNRNP70, KHSRP, C1QBP, RPL35, DENR, NUDT16, RPS13, HSP90AA1, CLUH, NCBP2, RPS5, PABPC4, RPS6, RPL13A, MRPS7, RC3H2, TSN, EEF1A1, RBMXL1, ESRP1, LUC7L3, PABPC1, SNRPC, LUC7L2, SLBP, MVK, RBM8A, SRSF1, MRPL13, ZFP36L1, PURB, PCBP1, TRA2B, G3BP1, TPR, RPS3, G3BP2, RPS2, IGF2BP2, PAIP2, SF3B1, HNRNPA3, CPSF6, CPSF1, MBD2, LSM1, UPF3B, RPS26, RPS3A1, HNRNPD, HNRNPC, CALR, EIF3A",3206,142,17446,2.452584503,1.70E-09,1.31E-10,1.25E-10
GOTERM_MF_DIRECT,GO:0003824~catalytic activity,152,4.087120194,1.43E-12,"CDA, ACAA2, EPRS, PBLD2, PNP, ABHD11, SCP2, PPME1, NRD1, PMPCB, GLUL, PHYH, PCYT2, PPTC7, ECH1, ACSL6, TALDO1, ACSL5, MOGS, ACSL3, GTF2F2, UPB1, ERN2, ACLY, MTHFD1, ILVBL, MTHFD2, UQCRC1, SUCLG2, SUCLG1, UQCRC2, SLC27A2, GNE, SLC27A4, TSTA3, PFKFB4, DNMT1, PDXDC1, SHMT1, LYZ1, ABHD6, PLD1, GNS, PLD3, ACAT2, ACAT1, LDHA, MAN2A1, MARC2, HLTF, ISOC1, ASL, FDFT1, EPHX1, GOT2, DHCR24, PRDX6, PAICS, AZIN1, DERA, CPS1, FASN, MYO5B, ALDH18A1, PAM, OGT, ALAS1, TREH, RDH7, GPT, MED16, AACS, HK2, ALAD, GYS1, HINT1, HINT2, ATIC, SPTLC1, SPTLC2, IDS, HMGCS2, ME2, UPP1, ADSL, CAMK1D, TPI1, HMGCS1, GAA, PGAM1, CAD, SYN3, SYN2, YDJC, FH1, HADHB, PPM1A, HADHA, UGDH, PKM, BDH1, EHHADH, DPYD, PDE5A, ALDOC, ALDOB, TKT, FBP1, GART, FBP2, DCTN6, DDC, USP15, ECHS1, OAT, GALT, ACSS2, ODC1, SLC3A2, PPM1J, ACAA1A, SAMHD1, PAPSS2, SRM, PPM1G, PAPSS1, CKMT1, HMGCL, PAK1, NFS1, CKB, PAK3, ACSS1, PAK2, XDH, RRM1, FAHD1, MDH1, PKLR, GCH1, MDH2, NAGA, ELP3, GSTZ1, PFKL, SUCLA2, PSAT1, IMPDH1, CTH, IMPDH2, GALM, PFKP",3206,479,17446,1.726793577,3.18E-09,2.27E-10,2.18E-10
GOTERM_MF_DIRECT,GO:0005524~ATP binding,377,10.13713364,1.70E-11,"EIF4A2, EIF4A1, PANK3, VARS, DQX1, EIF4A3, ARAF, TESK1, HNRNPU, SMC3, MKI67, EPRS, SMC4, ACTB, NUBP1, MYLK, UBE2L3, RPS6KA4, RPS6KA1, CHORDC1, LONP1, PDK3, AKT1, KIF21A, PIP4K2C, PRKACA, SEPHS2, GLUL, PRKACB, EPHB4, PDK2, EPHB3, DDX17, PRKCI, PRKCD, MYO7B, ACSL6, ACSL5, PRKCA, CSNK1D, AARSD1, ACSL3, LARS2, CDC34, DDX39B, MTHFD1, KARS, TEP1, SUCLG2, ULK1, IDNK, TRIB1, PI4K2A, CFTR, GNE, DHX9, HSPA4L, TWF1, ABCB9, PRKCZ, ATP5B, DHX32, MYO6, HLTF, DHX36, PIP5K1B, TRPM4, CDK18, TRAP1, CHKB, CHKA, PLK1, SMARCA5, SMARCA2, PAICS, CCT6A, ICK, EHD1, MOV10, GLUD1, QARS, WNK1, MYO5B, MYO5C, HYOU1, ALDH18A1, FARSA, ITM2B, ITM2C, FARSB, DDR1, TOP2A, SMG1, PRKAG1, ADK, OLA1, PRKAG2, KIF11, AACS, KHK, ACTR1A, GUK1, RARS, RFK, PBK, DHX15, KIF1B, TK1, JAK1, CCT3, CCT2, WARS, SPHK2, ITPK1, MINK1, NME2, KIF24, SYN3, BAZ1B, SYN2, NME1, KIT, TCP1, FAM20B, GARS, GART, GUCY2C, TOR4A, DTYMK, RNASEL, NLRP1A, ATP5A1, ADCY1, ADCY6, EGFR, PAPSS2, PAPSS1, PAK1, ASNA1, CCT8, CKB, PAK3, CCT7, ABCB1A, PAK2, CCT5, CCT4, MAP4K4, DYNC1H1, NPM1, MAP3K1, PKLR, RYK, RIOK3, CSNK1A1, GSS, UBE2G1, HIPK1, PSMC5, PSMC6, PSMC3, TAOK3, PSMC4, ETNK1, PSMC1, MARS, STK17B, PKN2, FRK, NDUFA13, DGKD, UBE2D3, PEBP1, IGF1R, ACTG1, NARS, SLK, KIF5B, RUVBL2, STK16, PAPOLA, PIM3, PIM2, MAP2K3, TOR3A, ABCG8, ABCG5, MAP2K2, LIG1, CASK, SARS, WRNIP1, UBE4B, ATP1B1, GTF2F2, ATAD3A, DGKZ, NRBP1, NAIP2, ACLY, ERN2, NAIP5, MAPKAPK2, CMPK1, SNRNP200, FKBP4, SLC27A2, NAIP1, ATP6V1A, PFKFB2, DDX6, PXK, VCP, PFKFB4, DDX5, PKDCC, UBA5, DDX1, AK2, TARS, AK3, AK4, HSP90B1, NLRP6, IRAK1, GRK4, STK38, G3BP1, PMVK, PGK1, EP400, ABL2, MYH14, IP6K1, NADK, MARK2, HSPA9, HSPA8, EIF2B2, UBE2I, UBE2B, HSPA5, UBE2C, HSPA4, ATP8B1, ASNS, TIMM44, TOR1B, CLK2, CDK9, CLK1, UBE2W, CDK8, GCLC, STK24, CPS1, UBE2S, CDK4, TRP53, UBE2N, CDK1, UBA2, SKIV2L, UBA1, IARS, UBE2K, FGFR3, MAP3K11, GALK2, UBE2M, GALK1, ABCD4, GSK3B, GSK3A, HSP90AB1, ABCD3, DDX3X, MCM7, SRXN1, DDX46, MCMDC2, MAST3, CHD8, MAST2, CHD7, ATP2A3, ATP2A2, CHD4, CHD3, UBE2D2A, PIK3C2A, HK2, UBE2Q1, MYO18A, PRKG2, ABCC3, ACTR3, ACTR2, HSP90AA1, CAMK1D, ABCC2, ATP6AP1, RFC1, ATRX, CAD, HUNK, DDX54, TGFBR1, DDX19B, PKM, UBE2R2, THRAP3, PEX6, HKDC1, PCCB, ATP6V1B2, MCM3, MYH9, PIK3C3, MVD, MCM5, MCM6, SKIV2L2, MCM2, CAMK2B, PRPS2, PDXK, DDX27, ACSS2, MVK, DDX24, ROCK1, SRC, ROCK2, DDX21, ATP1A1, ATP2C2, CLCN3, HSPD1, CKMT1, MAT2A, ERBB2, MKNK2, PTK2B, MAPK1, CSK, ACSS1, ATP9A, PRPS1L3, MAPK4, MAPK3, ABCF1, DDX39, RRM1, MYO10, IDH3G, ATP13A1, LIMK2, ATP2B1, HSPE1, MAPK14, CDK11B, MAPK13, DNAJA1, BCKDK, MYO1D, SNRK, PFKL, MYO1B, P2RX4, SUCLA2, MYO1A, DNAJA3, DNAJA2, ATP13A3, PFKP, TAF1",3206,1507,17446,1.361320699,3.77E-08,2.51E-09,2.41E-09
GOTERM_MF_DIRECT,GO:0042803~protein homodimerization activity,222,5.969346599,2.43E-11,"CDA, FAAH, GABPB2, TFRC, PLEKHB1, CISD2, RPL7, EFR3A, RPS19, CREB3L3, SCP2, NAMPT, REG1, PDK2, HES6, ACTN1, ACSL6, ACTN4, SLC51A, BHLHA15, JMJD6, KCNQ1, VPS25, ATF3, MAOB, CTBP2, CTBP1, SHMT1, MYCBP2, MGST1, PDGFA, ABCB9, ZBTB4, ADH5, SNX1, ADH1, PRDX4, SNX2, GRPEL1, PDCD10, S100A16, PRDX1, PRKAR2A, GRPEL2, S100A13, ZBTB7B, S100A10, SNX6, GSTM4, FZD1, GSTM3, GSTM2, JUN, GSTM1, CHKA, HOMER2, H13, AIMP1, GNPTG, FASN, ID1, GSTM7, CEP57, CLIC6, TOP2A, ARF1, HEXB, BHLHE41, SPPL3, TRIM8, ATIC, IMPA1, HNF4A, CHMP1A, MLX, ANXA6, MUC13, GIT1, ATPIF1, CACYBP, ANO6, COMMD1, DYNLL1, TOX3, CEACAM1, KIT, DPYD, TKT, MGLL, PAFAH1B1, ODC1, CRYBA2, HSD17B4, PTS, HSF2, AGR2, XDH, RUNX1T1, NPM1, GCH1, GSS, GSR, KLHL2, TARBP2, VEGFA, FKBP1A, DGKD, PDCD6, SPPL2A, CPOX, PARK7, NR3C1, PYCARD, SLK, RUVBL2, BANF1, NUDT16, SH3GLB1, TPD52, BNIP3L, USP7, DGAT2, S100A1, TPM1, FOXP4, NRBP1, APOA1BP, FOXP1, OXA1L, GPD1, S100A6, CHMP4B, SQSTM1, TSG101, CUL3, FAM109A, RAP1GAP, ACAT1, DPP4, SDCBP, IRAK1, TPR, MCL1, CBX5, AMBP, IDH1, GOT2, HPS4, ASNS, HPRT, NFKB1, QDPR, VIL1, GRHPR, SP1, BHLHE40, CRYL1, ALPI, TCF3, BCL2L2, MAP3K11, ABCD3, THRA, LDB1, CPQ, DPY30, ECE1, ELAVL1, GHR, SPR, PRKG2, AMICA1, BOK, BCAS1, HSP90AA1, PDCD6IP, DST, HMGCS1, APOA4, ADRA2A, QTRT1, RABEP1, G6PDX, CAT, BIRC5, MYH9, MVD, ANG, ALDH9A1, CAMK2B, PRPS2, CEBPA, PDXK, GTF2A2, CANT1, CEBPG, HMGCR, RCHY1, RNF4, MFF, CLN6, SRM, HMGCL, NFS1, OXCT1, HES1, BAK1, MAPK4, TXNRD1, BNIP3, SGTA, HIP1R, NAGA, USF2, GSTZ1, GALE, TEF, XPNPEP1, SYT11, APOC2, BAX, GALM",3206,798,17446,1.513848564,5.39E-08,3.37E-09,3.23E-09
GOTERM_MF_DIRECT,GO:0031625~ubiquitin protein ligase binding,99,2.662005916,5.20E-11,"UBE2L3, ACTG1, HERC2, TUBB5, TRIM28, MYC, PRKACA, PRKACB, GABARAPL2, GABARAPL1, USP7, STX8, CDC34, PRKAR1A, UQCRC1, UBE2V2, TXNIP, UBE2V1, TRIB1, ATF6, SQSTM1, ANAPC2, VCP, TSG101, CUL3, PIK3R1, HIF1A, BAG6, BTBD1, PRKAR2A, BTBD2, PCBP2, HLTF, HSPA9, HSPA8, UBE2B, HSPA5, UBE2C, H13, PA2G4, SMAD5, PRDX6, UBE2W, MC1R, UBE2S, TRP53, UBE2N, SRPRB, CALR, UBE2K, H2-AB1, YWHAE, GSK3B, CDKN1A, UBXN1, FAF1, ARRB1, GPI1, MAP1LC3B, TUBA1B, SIPA1L1, SUMO1, SLC22A18, SUMO2, JAK1, BOK, CCT2, TPI1, PAX6, AXIN2, RANGAP1, YWHAZ, TGFBR1, TRAF4, UBE2R2, TCP1, NDUFS2, TMBIM6, EIF4E2, SLC25A5, RALA, DERL1, NEDD8, USP19, EGFR, HSPD1, ERBB2, SPOP, CKB, RNF20, RPA2, UBE2G1, LRPPRC, DNAJA1, APC, SYT11, JKAMP, LTBR, CUL4B",3206,284,17446,1.896920826,1.15E-07,6.77E-09,6.49E-09
GOTERM_MF_DIRECT,GO:0051082~unfolded protein binding,39,1.048668997,2.33E-10,"HSP90AB1, TOMM20, HSP90B1, ERLEC1, NUDCD2, DNAJB6, GRPEL1, GRPEL2, CCT8, CCT7, UGGT1, SRSF10, CCT5, CCT4, HSPA9, CCT3, CCT2, TRAP1, HSPA8, HSP90AA1, NPM1, NUDC, HSPA5, ST13, CCDC115, PTGES3, UBE4B, HSPE1, DNAJA1, CCT6A, DNAJA3, CDC37, TCP1, CANX, DNAJA2, SCG5, PFDN1, CALR, PFDN5",3206,75,17446,2.82966937,5.17E-07,2.87E-08,2.75E-08
GOTERM_MF_DIRECT,GO:0051287~NAD binding,31,0.833557408,1.83E-09,"AHCYL2, AHCY, AHCYL1, CTBP2, HIBADH, CTBP1, HSD17B10, ADH4, ADH1, CYB5R3, IDH3B, PHGDH, ME2, NDUFV1, IDH3A, PARP1, MDH1, IDH3G, IDH1, IDH2, SORD, HADHB, GRHPR, UGDH, HADHA, GPD1, NDUFS2, DLD, GAPDH, GLYR1, ALDH9A1",3206,55,17446,3.067124142,4.06E-06,2.14E-07,2.05E-07
GOTERM_MF_DIRECT,GO:0004364~glutathione transferase activity,22,0.59155687,1.19E-08,"GSTM4, GSTK1, GSTM3, GSTM2, GSTM1, GSTO1, MGST3, GSTP1, GSTT3, MGST1, MGST2, GSTT1, EEF1G, GSTZ1, GM3776, GSTA4, GSTA3, GSTA2, GSTA1, GSTM7, GSTM6, GM10639",3206,33,17446,3.627781244,2.65E-05,1.32E-06,1.27E-06
GOTERM_MF_DIRECT,GO:0003743~translation initiation factor activity,34,0.914224254,1.41E-08,"EIF4A2, EIF4A1, EIF4H, EIF2S3X, DENR, EIF2B1, EIF4B, EIF2A, MCTS1, EIF5B, EIF2B2, EIF1AX, EIF2S2, EIF2S1, EIF1, EIF3M, EIF5, EIF6, EIF3K, EIF3L, EIF3I, EIF3G, EIF3H, EIF3E, EIF3F, EIF3C, EIF1A, EIF4E2, EIF3D, EIF1B, EIF3A, EIF4G2, EIF4G1, EIF3B",3206,68,17446,2.720835933,3.13E-05,1.49E-06,1.43E-06
GOTERM_MF_DIRECT,GO:0009055~electron carrier activity,29,0.779779511,1.63E-08,"ACADVL, NDUFA12, COX7A2, UQCR11, ETFA, GLRX, ETFB, COX7A1, ACADL, CYC1, ACADM, ACAD11, ACADS, XDH, GLRX3, PTGES2, GLRX5, CYBA, SDHC, SDHA, ACADSB, SDHB, POR, COX7A2L, ACOX1, FDX1, CYCS, NDUFS1, CIAPIN1",3206,53,17446,2.977518568,3.62E-05,1.64E-06,1.58E-06
GOTERM_MF_DIRECT,GO:0016853~isomerase activity,47,1.263780586,4.78E-08,"FKBP11, TOP2A, PBLD1, TSTA3, FKBP2, ISYNA1, HSD17B4, FUOM, PBLD2, GPI1, EBP, MCEE, HYI, PGM2, ACADM, TXNDC5, NKTR, PDIA3, PPIL1, TPI1, HMGCS1, PTGES2, PGAM1, PTGES3, ECH1, ITPK1, PMM2, MIF, PDIA6, PDIA5, APOA1BP, FKBP1A, GSTZ1, GALE, DKC1, EHHADH, PPIF, FKBP8, PIN1, GALM, TOP1, P4HB, PPIG, FKBP4, PPIB, PPIA, PPID",3206,115,17446,2.223987632,1.06E-04,4.60E-06,4.42E-06
GOTERM_MF_DIRECT,"GO:0046933~proton-transporting ATP synthase activity, rotational mechanism",13,0.349556332,9.13E-08,"ATP6AP1, ATP5A1, ATP5C1, ATP5G3, ATP5H, ATP5G2, ATP5F1, ATP5O, ATP5G1, ATP5L, ATP5B, ATP5E, ATP5D",3206,14,17446,5.052981018,2.02E-04,8.43E-06,8.09E-06
GOTERM_MF_DIRECT,GO:0051015~actin filament binding,51,1.371336381,1.01E-07,"ARPC1B, ARPC1A, ESPN, LASP1, SIPA1L1, CAPZB, CFL1, MYO18A, PLS1, ACTR3, ACTR2, DBNL, ACTN1, TPM1, SHROOM3, ACTN4, MTSS1, FRG1, PICK1, MYH9, LCP1, UTRN, EZR, DBN1, GAS7, USH1C, IQGAP2, EGFR, CORO1B, SSFA2, CORO1C, LIMA1, MYO6, MICALL2, CTNNA1, MYH14, EPS8L2, MYO10, HIP1R, DSTN, ARPC4, ARPC5, CORO2A, EEF2, MYO1D, VIL1, MYO1B, ARPC2, MYO1A, ARPC3, CAPZA1",3206,132,17446,2.10246413,2.23E-04,8.91E-06,8.55E-06
GOTERM_MF_DIRECT,GO:0016787~hydrolase activity,358,9.626243614,2.45E-07,"EIF4A2, CDA, EIF4A1, POP5, AHCYL2, FAAH, AHCYL1, PGAP1, DQX1, GDE1, NUDT4, GLS, LIPE, DPYSL2, LIPH, ANPEP, LONP1, PRSS8, ATP6V1E1, HABP2, DDX17, SACM1L, ENTPD5, MOGS, RNASE4, CMBL, HDHD3, UPB1, RNASE1, 4931406C07RIK, INPP4A, ACE2, POR, DDX39B, MTHFD1, PPA1, MTHFD2, CLPP, XRN2, ACOT2, ACOT1, PLBD1, LAP3, ADPRM, CFB, CFTR, GNE, ENPEP, MTMR3, KLK1, DHX9, GNS, ZMPSTE24, TRPM2, ATP5B, DHX32, ATP5E, HLTF, DHX36, INPP5J, AMZ2, LTA4H, RCE1, CTSA, ST14, PTPRN2, FUCA1, SMARCA5, H13, SMARCA2, PRDX6, PAFAH2, MOV10, FASN, PPT1, ITPA, LGMN, PCSK1, ACY1, HEXB, CTSZ, HEXA, OLA1, PCSK9, PTPRK, PEPD, PCSK5, SPPL3, PTPRF, PTPRG, ANKRD9, SMPD3, PPP3CA, SMPD2, HINT1, ATIC, HINT2, IMPA1, CTSL, DHX15, IDS, CD38, CTSF, CTSD, CTSB, LYPLA1, CNOT6L, TPSG1, MME, DUSP1, GAA, PGAM1, ITPK1, AMPD2, SIRT7, NUDT16L1, BACE1, PSMA5, GCHFR, MAN1A, PSMA6, BACE2, IMMP1L, PSMA3, PLCB3, PSMA4, PSMA1, PSMA2, GARS, PAFAH1B3, MPND, MGLL, ATP6V0E, ASAH1, RNASEL, ASAH2, TMPRSS4, GDPD1, TMPRSS2, PSMA7, NT5C, PPP2CA, PSMB6, PPP2CB, PSMB7, PSMB4, PSMB5, PSMB2, PSMB3, ASNA1, PSMB1, ABCB1A, BCHE, GCH1, USP9X, PSMB8, PPP1CA, AGMAT, NUDT9, SPCS2, PSMC5, PSMC6, SPCS1, AADAC, PSMC3, PSMC4, PSMC1, ENGASE, PNPLA2, DCLRE1C, GDA, SPPL2A, INPPL1, PARK7, APEH, CNDP2, PPP1CB, NPEPPS, ABHD11, NRD1, PLAU, PPME1, RUVBL2, MACROD1, NUDT19, PMPCB, CAPN1, NUDT16, GGT1, USP7, G6PC, PPTC7, SLX1B, ACOT11, SSU72, ACOT13, WRNIP1, GTF2F2, CTDNEP1, PLA2G16, ERN2, MINPP1, PGP, RPP21, SNRNP200, PHPT1, ATP6V1A, IDI1, DDX6, VCP, PFKFB4, DDX5, RNASEH2A, PSMD14, DDX1, LYZ1, ABHD6, PSEN1, PLD1, PLD3, DPP3, DPP4, MAN2A1, AMDHD2, ESD, G3BP1, EP400, MGEA5, ATP8B1, CPSF3, EPHX1, TOR1B, SSH2, ISG20, PTPRD, COPS5, G6PC3, CPD, CPE, TPP1, PNLIPRP2, USP38, DAGLA, DDX3X, MCM7, DDX46, CPQ, CHD8, USP33, TREH, CHD7, USP34, ATP2A3, PTEN, ATP2A2, ADAR, CHD4, ECE1, DUSP18, MYSM1, CES2A, DUSP11, SCPEP1, CASP7, CES2E, ABHD16A, CASP6, ACP6, CES2G, CASP1, CASP2, ACP5, PGLS, PGPEP1, ACP1, HGFAC, EIF5B, PLA2G12A, MMP7, ANG4, DESI1, ATRX, CAD, ABHD14B, DDX54, YDJC, TSN, DNM1, DNM2, DUSP22, PPM1A, PTP4A2, MEP1B, CTDSP2, ATP6V1B2, MCM3, PDE5A, MCM5, ANG, HAGH, MCM6, FBP1, DCTPP1, SMPDL3A, SKIV2L2, FBP2, LTF, MCM2, TMEM55B, USP15, DDX27, CANT1, DDX24, HDAC1, USP10, PON2, DDX21, FURIN, PPM1J, ABHD17C, ATP1A1, ATP2C2, SAMHD1, NT5C3, PSMB10, USP19, PPM1G, DNPEP, POLD1, NT5DC3, FAM63B, FAM63A, BPNT1, SEC11A, ATP9A, SEC11C, USP24, DDX39, PLA2G2F, FAHD1, ATP13A1, USP22, PLA2G2A, DDHD2, NAGA, ATP2B1, TMPPE, PNKD, CES1D, XPNPEP1, GNPDA2, ABHD17A, ERCC4, CES1F, EIF3F, ATP13A3, LPIN2, METAP2",3206,1533,17446,1.270788342,5.44E-04,2.06E-05,1.97E-05
GOTERM_MF_DIRECT,GO:0008022~protein C-terminus binding,70,1.882226405,2.50E-07,"CLIC6, TOP2A, YWHAB, PLEKHB1, CLTC, ATP2A2, YEATS4, CIB1, MKI67, PHB2, PQBP1, PSMD9, PPP1CC, NIPBL, YWHAQ, AP1G1, EP300, BANF1, USP7, DBNL, CASK, LMO7, DYNLL1, ATP1B1, MIF4GD, SREBF2, DNM1, PPM1A, NCL, PEX6, SARNP, CDC37, PEX5, PICK1, PABPC1, OPTN, ATF4, PXK, ANP32A, SRC, ITPR1, AKAP7, FBLN1, PIK3R1, PHB, PPP2CA, PRDX3, SDCBP, STIP1, PPP2CB, ERBB2, RABAC1, PEX16, UBE2I, MID1IP1, PRRC2C, SYNJ2BP, MAPK14, DLG1, SNX17, ERCC4, SP1, TRP53, NEDD4, ID1, CTNNB1, SDC1, VIM, SAE1, TJP2",3206,209,17446,1.822569524,5.55E-04,2.06E-05,1.97E-05
GOTERM_MF_DIRECT,GO:0008134~transcription factor binding,102,2.742672761,2.75E-07,"FOXA1, ATF2, KDM1A, KEAP1, NUCKS1, RORB, PARK7, NR3C1, CHCHD2, CCND1, PSMD4, MYC, RPS6KA1, EP300, ARID2, JUNB, HES6, USP7, CSNK2B, TRIB1, ZFPM1, PPID, ATF4, CTBP1, GATA6, PIK3R1, GATA3, HIF1A, NEUROD1, BPTF, NKX2-2, EGR1, HSPA8, JUN, JUND, UBE2I, NFATC3, IRF2BP1, CDK9, MLXIPL, HNRNPK, SP1, TRP53, HNRNPF, BCL3, ID1, HNRNPD, ID3, UBA2, TCF3, OGT, H2-AB1, GSK3B, DDX3X, THRA, PTPRN, FHL2, HMGB2, ARRB1, CHD4, YBX1, SUMO1, HNF4A, C1QBP, MLX, PARP1, PAX6, FOS, YWHAZ, EPN1, MED25, PPARA, CEBPA, GTF2A2, PCNA, HDAC1, CEBPG, TAF9, CXXC5, RNF4, PURB, RXRA, CREG1, UBN1, RPS3, MAPK1, HES1, TCF7L2, NPM1, STAT3, WWP2, KLF4, PSMC5, KLF5, MYBBP1A, NFIA, ABI1, CTNNB1, FOXA3, TPT1, FOXA2, TAF1",3206,342,17446,1.622954767,6.08E-04,2.17E-05,2.08E-05
GOTERM_MF_DIRECT,GO:0008137~NADH dehydrogenase (ubiquinone) activity,21,0.564667921,3.40E-07,"NDUFB9, NDUFA8, NDUFB8, NDUFA7, NDUFA13, NDUFB7, NDUFA5, NDUFA4, NDUFA12, NDUFB4, NDUFA2, NDUFC2, AA467197, NDUFS8, NDUFS7, NDUFS4, NDUFS3, NDUFS2, NDUFS1, NDUFV2, NDUFV1",3206,35,17446,3.265003119,7.54E-04,2.60E-05,2.49E-05
GOTERM_MF_DIRECT,GO:0016740~transferase activity,343,9.222909384,5.55E-07,"ATF2, LPGAT1, PANK3, CMAS, EHMT2, ARAF, TESK1, EHMT1, ZDHHC3, MYLK, UBE2L3, RPS6KA4, PNP, HERC2, SCP2, RPS6KA1, NAMPT, PDK3, AKT1, TRIM25, PIP4K2C, PRKACA, SEPHS2, PRKACB, EPHB4, PDK2, EPHB3, GSTK1, CPT1A, PRKCI, ALG6, ALG5, PRKCD, TALDO1, PRKCA, CSNK1D, SULT2B1, CDC34, SOAT1, SOAT2, ULK1, IDNK, PI4K2A, GNE, CDS1, RPN2, MGST3, SHMT1, RPN1, MGST1, PRKCZ, OSGEP, ST3GAL4, DPH5, B4GALNT1, PIP5K1B, ST3GAL6, B4GALNT2, ST3GAL1, FDFT1, NAA50, GSTM3, CDK18, GSTM2, GSTM1, CHKB, CHKA, SETD1B, PLK1, EPT1, CS, ICK, SULT1B1, WNK1, FASN, NMT1, ALDH18A1, GSTM7, GSTM6, DDR1, MOCS2, ZCCHC11, SMG1, SETD3, MOGAT2, SETD7, ADK, GPT, KHK, GYS1, ATIC, SPTLC1, SPTLC2, GUK1, RFK, REV3L, PBK, CD38, TK1, JAK1, ELOVL1, PRMT5, PARP1, GSTO1, PRMT1, SPHK2, NSUN2, ITPK1, MINK1, NME2, ASH1L, BAZ1B, APRT, NME1, HADHB, SULT1D1, B3GNT7, KIT, FAM20B, CHST4, TKT, GART, CHST2, DTYMK, OAT, ZDHHC20, GSTP1, PRIM1, SGMS2, ACNAT1, EGFR, PAPSS2, PAPSS1, PAK1, CHRAC1, NSD1, GCNT3, MGAT1, MGAT2, CEPT1, CKB, PAK3, PAK2, MAP4K4, MAP3K1, PKLR, RYK, RIOK3, CSNK1A1, TRMT1, UBE2G1, WWP2, ELP3, HIPK1, GSTA4, TAOK3, ZDHHC9, GSTA3, GSTA2, ETNK1, NEDD4, LPCAT3, STK17B, PKN2, CRAT, FRK, OTC, GALNT12, ACAA2, UBE2D3, COMT, SAT1, GALNT10, IGF1R, FBL, SLK, FNTA, STK16, PAPOLA, EP300, PIM3, PIM2, GGT1, TGM2, MAP2K3, PCYT2, DGAT2, MAP2K2, DGAT1, CASK, DGKZ, TPST2, TPST1, ACLY, ERN2, ILVBL, MAPKAPK2, CMPK1, DNMT1, PFKFB4, PKDCC, AK2, AK3, GSTT1, UAP1, AK4, ACAT2, ACAT1, FUT8, EMG1, IRAK1, GRK4, STK38, UAP1L1, PMVK, SMYD2, ABL2, SMYD3, IP6K1, NADK, MARK2, FDPS, UBE2B, UBE2C, GFPT1, GOT2, HPRT, CRLS1, CLK2, CDK9, CLK1, UBE2W, CDK8, COQ2, NAT8, STK24, UBE2S, CDK4, STT3A, UBE2N, CDK1, STT3B, UBE2K, OGT, FGFR3, MAP3K11, GALK2, GALK1, GSK3B, GSK3A, GAL3ST1, B4GALT1, ALAS1, ST6GALNAC2, MAST3, MAST2, UBE2D2A, PIK3C2A, HK2, POLB, GMPPB, MRPL2, CPT2, UBE2Q1, GMPPA, PRKG2, UGT2A3, HMGCS2, UPP1, WHSC1, CAMK1D, HMGCS1, CAD, DNMT3A, HUNK, TGFBR1, DDOST, QTRT1, PKM, UBE2R2, DAD1, HKDC1, UGT2B5, PIK3C3, B4GALT6, B4GALT5, CAMK2B, PRPS2, AGPAT5, PDXK, GALT, MVK, ROCK1, SRC, ROCK2, ACAA1A, AGPAT1, NT5C3, AGPAT2, AGPAT3, SRM, CKMT1, NFS1, HECTD1, UGP2, MAT2A, TNKS2, HECTD3, POLR2B, OXCT1, POLD1, POLD2, ERBB2, MKNK2, PTK2B, MAPK1, POLR2G, CSK, CDIPT, UGGT1, MAPK4, MAPK3, GALNT7, GALNT6, GALNT4, NAA10, GALNT2, GALNT1, LIMK2, MAPK14, CDK11B, MAPK13, GSTZ1, BCKDK, SNRK, PFKL, PSAT1, MGAT4A, MGAT4B, CHPT1, NAGS, PFKP, TAF1",3206,1472,17446,1.267998268,0.001230197,4.10E-05,3.93E-05
GOTERM_MF_DIRECT,GO:0031489~myosin V binding,15,0.40333423,6.15E-07,"RAB3B, RAB3C, FUS, RAB3D, RAB27A, RAB27B, RAB11A, RAB11B, RAB10, MLPH, RAB14, RAB25, NPC1L1, RAB6A, RAB8A",3206,20,17446,4.081253899,0.001362773,4.40E-05,4.22E-05
GOTERM_MF_DIRECT,GO:0019903~protein phosphatase binding,37,0.9948911,7.00E-07,"PPP1R15A, YWHAE, VCP, CDKN1B, STX17, MVP, CTNND1, ITPR1, PIK3R1, IQGAP1, EGFR, HSP90B1, GHR, PPP2CA, SNX3, PPP1CC, CDH1, PPME1, PPP6R1, ERBB2, STAT6, CSK, REG1, KCNN4, JAK1, HSP90AA1, JUP, BAD, STAT3, RPA2, AP3B1, MAPK14, CEACAM1, TRP53, PARD3, CTNNB1, ANAPC5",3206,88,17446,2.287975671,0.001549137,4.84E-05,4.65E-05
GOTERM_MF_DIRECT,GO:0004298~threonine-type endopeptidase activity,16,0.430223178,9.75E-07,"PSMB10, PSMA7, PSMB8, PSMB6, PSMA5, PSMB7, PSMA6, PSMB4, PSMA3, PSMB5, PSMA4, PSMA1, PSMB2, PSMB3, PSMA2, PSMB1",3206,23,17446,3.785510863,0.002157613,6.55E-05,6.28E-05
GOTERM_MF_DIRECT,GO:0042277~peptide binding,38,1.021780048,1.11E-06,"ITGB1, ENPEP, RNPEPL1, CLTC, H2-K1, RPLP0, CLTB, H2-Q4, CLTA, FURIN, H2-Q1, PCSK5, CRIP1, DPP4, NPEPPS, FNTA, NLRP6, CTSL, ANPEP, LTA4H, CTSD, CTSB, NKTR, HSPA8, MME, CSNK1A1, GSS, CSNK1D, PPIF, ANG, TPP1, ADNP, CALR, PPIB, PPIA, OGT, PPID, H2-D1",3206,93,17446,2.223478827,0.002466611,7.26E-05,6.97E-05
GOTERM_MF_DIRECT,GO:0003682~chromatin binding,128,3.441785426,1.15E-06,"ATF2, KDM1A, ZMYND8, NUCKS1, TTF1, SMC3, NR3C1, HMGN5, TRIM28, CREB3L1, EP300, SOX9, HMGN3, HMGN1, SMARCC1, SMARCC2, HCFC1, FOXP1, MORF4L1, RBMXL1, CSNK2B, TFAM, ADNP, NUPR1, ATF5, ANKRD17, ENY2, DNMT1, CTBP2, SHMT2, DDX1, TSHZ1, GATA6, GATA3, PHF21B, PLAC8, NEUROD1, ZNHIT1, KCNQ1OT1, RAD21, TPR, EP400, TNRC18, NKX2-2, KLHDC3, CBX7, JUN, CBX5, NONO, PHF12, NFATC3, SMARCA2, NFKB1, NFKB2, CDK9, TRP53, HNRNPD, CDK1, TCF3, RERE, KDM5A, TOP2A, LDB1, CITED2, CHD8, SETD7, HP1BP3, YBX1, CTCF, NIPBL, SIN3B, UBTF, WHSC1, JARID2, NELFE, KDM6B, BRD3, TGIF1, SREBF1, BRD2, PRMT5, PBRM1, NCOA5, PARP1, H2AFY, EED, ATRX, DNMT3A, PAX6, SIRT7, ASH1L, FOS, BAZ1B, SAFB, CBFA2T3, SREBF2, MSL1, DNAJC2, TOX3, SFPQ, NCOR1, WAC, CKS2, MCM5, TOP1, ZMYND11, 2810417H13RIK, PCNA, HDAC1, CENPB, EGFR, CUX1, POLR2B, NSD1, POLD1, HES1, SF3B1, RNF20, MBD3, TCF7L2, MBD2, SSRP1, REC8, FABP1, NFIA, CTNNB1, NCAPD2, SSBP1",3206,466,17446,1.494708152,0.002553178,7.30E-05,7.00E-05
GOTERM_MF_DIRECT,GO:0031072~heat shock protein binding,26,0.699112665,1.55E-06,"FAF1, CLTC, NR3C1, ZFP36, DNAJB6, IRAK1, LMAN2, TPR, BAK1, SLC18A2, HSPA9, HSPA8, NFKB1, DNAJA1, HNRNPK, DNAJC7, DNAJA3, CDC37, DNAJA2, OGDH, TFAM, BAX, DNAJC9, FKBP4, ATF5, PPID",3206,53,17446,2.669499406,0.003425904,9.53E-05,9.14E-05
GOTERM_MF_DIRECT,GO:0051020~GTPase binding,18,0.484001076,1.61E-06,"STOML2, HSP90AA1, PTPRN, BNIP3, YBX1, EPRS, MARCH5, AIMP1, GOLGA4, GNB2, GNB1, VPS41, PREB, LCP1, IARS, PAK3, SPTBN1, SH3GL1",3206,29,17446,3.377589434,0.003552637,9.62E-05,9.22E-05
GOTERM_MF_DIRECT,GO:0019843~rRNA binding,24,0.645334767,2.88E-06,"PTCD3, MRPS17, RPL5, NPM1, MRPS15, RNASEL, RPS9, IMP3, RPS5, RPL12, RPL11, DDX21, RPL23A, MRPS7, RPL8, RPL9, MRPL11, RPS4X, MRPL20, EMG1, RPS18, RPL37, RPS11, NOL12",3206,48,17446,2.720835933,0.006354249,1.68E-04,1.61E-04
GOTERM_MF_DIRECT,GO:0003954~NADH dehydrogenase activity,11,0.295778435,7.17E-06,"NDUFA9, NDUFA13, NDUFB8, NDUFB7, NDUFS8, NDUFS7, NDUFS3, NDUFS2, NDUFS1, NDUFV2, NDUFV1",3206,13,17446,4.604491578,0.015770277,4.08E-04,3.91E-04
GOTERM_MF_DIRECT,GO:0051087~chaperone binding,31,0.833557408,9.90E-06,"CDKN1B, TFRC, ATP1A1, HSPD1, STIP1, DNAJB6, GRPEL1, BAG1, GRPEL2, HES1, BAK1, LBR, GET4, PRNP, SDF2L1, ST13, AMFR, AHSA1, TIMM44, HSPE1, SOD1, DNAJA1, DNAJC3, TRP53, CDC37, ALB, DNAJC10, DNAJA2, OGDH, BIRC5, BAX",3206,75,17446,2.249224371,0.021696109,5.26E-04,5.04E-04
GOTERM_MF_DIRECT,GO:0000062~fatty-acyl-CoA binding,19,0.510890024,9.93E-06,"ACADVL, ACBD5, ACBD4, PITPNA, DBI, ETFA, ACADSB, HADHB, HMGCL, HADHA, ACADL, SOAT1, SCP2, ACOX1, SOAT2, HNF4A, ACADM, ACAD11, ACADS",3206,35,17446,2.954050441,0.021764776,5.26E-04,5.04E-04
GOTERM_MF_DIRECT,"GO:0016616~oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",18,0.484001076,9.97E-06,"HSD3B7, MDH1, CTBP2, MDH2, CTBP1, IDH3G, IDH1, IDH2, HMGCR, GRHPR, AKR7A5, UGDH, LDHA, FAM213B, GPD1, IDH3B, PHGDH, IDH3A",3206,32,17446,3.060940424,0.021842901,5.26E-04,5.04E-04
GOTERM_MF_DIRECT,GO:0003713~transcription coactivator activity,58,1.559559021,1.12E-05,"KDM5A, GMEB2, SETD3, SMARCB1, CITED2, PARK7, MED16, NR3C1, MYSM1, CCAR1, UBE2L3, PSMD9, TRIM28, EP300, JUNB, DDX17, MKL2, ARID5B, EDF1, HCFC1, ELF3, THRAP3, SUB1, CEBPA, DDX5, ENY2, GTF2A2, CTBP2, CBFB, MAGED1, TAF9, GATA3, NEUROD1, PDLIM1, PRDM16, TCEB2, PCBD1, SCAND1, NKX2-2, RNF20, RBM39, JUN, NPM1, JUND, JUP, FUS, TAF10, USP22, TRIP4, COPS5, SNW1, ARL2BP, NACA, JMY, CTNNB1, TCF3, LPIN2, TAF1",3206,180,17446,1.753427601,0.024486456,5.70E-04,5.47E-04
GOTERM_MF_DIRECT,GO:0003924~GTPase activity,65,1.747781662,1.13E-05,"RAB3B, RAB9, RAB3C, DDX3X, SRPR, RAB43, TUBA1C, TUBA1B, TUBB5, TUBA1A, RAC1, RAB8A, RAB2A, EIF5B, RHOG, GTPBP1, TUBA4A, RHOA, GTPBP4, DNM1, RAB33B, TUFM, GNL3, DNM2, EEF1A1, ARL4A, RRAGD, RHOU, ARF6, RALA, TUBAL3, ARL3, GNAI3, AGAP1, GSPT1, GNAI2, RAP1B, GNA13, CDC42, RAP1A, RRAS, GNG4, GNA11, EIF2S3X, RAB6A, RAB4A, RAB27A, RAB27B, TUBB4B, EEF2, RAB11A, RAB11B, GNAO1, RAB10, GNL3L, RAB14, GNAQ, GNB2, GNB1, GNAS, TSR1, KRAS, RAB17, RAB5A, RAN",3206,209,17446,1.692385987,0.024780788,5.70E-04,5.47E-04
GOTERM_MF_DIRECT,GO:0047485~protein N-terminus binding,42,1.129335843,1.31E-05,"SNAP25, HDAC1, SCT, DCTN4, ZMYND8, STXBP1, GLRX, PHB2, SDCBP, PPP1CC, NIPBL, SCFD1, YWHAQ, PDCD10, BANF1, PDLIM5, SMARCE1, EIF5A, NPM1, SMARCC1, PARP1, TPM1, RPA2, ACTN4, TARBP2, MORF4L1, HAX1, ERCC4, ACOX1, TRP53, ID1, PEX5, STX5A, EIF3E, CALM3, CALM1, CHMP6, CALM2, RPS21, VPS25, ARF6, PLEC",3206,117,17446,1.95342067,0.028627714,6.45E-04,6.19E-04
GOTERM_MF_DIRECT,GO:0019003~GDP binding,26,0.699112665,2.34E-05,"RAB3B, PRPS2, RAB9, ARF1, RALA, ARL3, GNAI3, RAP1B, RRAS, EIF2B1, RAB8A, RAB2A, RAB4A, RAB27A, RAB27B, RHOA, RAB11B, RAB10, RAB14, SUCLG2, SUCLG1, KRAS, RAB17, RAB5A, RAN, ARL8B",3206,60,17446,2.358057808,0.050547473,0.00112759,0.001081286
GOTERM_MF_DIRECT,GO:0051536~iron-sulfur cluster binding,27,0.726001613,2.76E-05,"ISCA1, IREB2, CISD1, CISD2, NUBP1, CISD3, NFS1, POLD1, PPAT, REV3L, UQCRFS1, NDUFV2, NDUFV1, XDH, GLRX3, GLRX5, ELP3, SDHB, NDUFS8, NDUFS7, DPYD, FDX1, NDUFS2, ACO1, NDUFS1, CIAPIN1, ACO2",3206,64,17446,2.295705318,0.059296841,0.00130057,0.001247162
GOTERM_MF_DIRECT,GO:0003779~actin binding,93,2.500672224,3.47E-05,"ITGB1, ARPC1B, ARPC1A, FBXO25, INPPL1, ARPC5L, FHL3, WASL, ESPN, MYLK, LASP1, CAPZB, TMSB4X, CFL1, DAG1, COTL1, YWHAG, YWHAH, PLS1, ACTR3, MKL2, ACTR2, DBNL, DST, TPM4, TPM3, ACTN1, TPM1, MYO7B, COBL, SHROOM3, ACTN4, MTSS1, MED28, CEACAM1, MAP1B, MAP1A, FRG1, PICK1, MYH9, ANG, LCP1, UTRN, EZR, PFN1, DBN1, PLEC, PXK, FLII, TWF1, ADD3, NCALD, CORO1B, CNN3, SSFA2, CORO1C, LIMA1, CLMN, MICAL1, MYO6, MYH14, EPS8L2, FLNB, PDLIM5, SPTBN1, VASP, MARCKSL1, GSN, MYO10, HOMER2, HIP1R, KLHL2, MICAL2, DSTN, ARPC4, ARPC5, CGN, PARVB, CORO2A, SSH2, MYO1D, VIL1, MARCKS, MYO1B, MLPH, ARPC2, MYO1A, ARPC3, CAPZA1, MYO5B, JMY, CAPZA2, MSRB1",3206,338,17446,1.497264744,0.074044764,0.001602668,0.001536854
GOTERM_MF_DIRECT,GO:0031492~nucleosomal DNA binding,20,0.537778973,3.77E-05,"SMARCE1, MBD3, SMARCC1, SMARCD2, SMARCB1, SMARCC2, H2AFY, H3F3B, H2AFZ, HDAC1, H3F3A, MBD2, CHD4, CENPA, ACTB, HMGN5, RBBP4, HNRNPC, HMGN3, HMGN1",3206,41,17446,2.654474081,0.080244403,0.001707056,0.001636955
GOTERM_MF_DIRECT,GO:0004602~glutathione peroxidase activity,13,0.349556332,4.19E-05,"GSTK1, GPX2, GPX1, GPX4, GPX3, MGST3, GSTP1, MGST1, MGST2, GSTT1, PRDX6, GSTZ1, GSTM7",3206,20,17446,3.537086712,0.088653614,0.001856606,0.001780364
GOTERM_MF_DIRECT,GO:0030544~Hsp70 protein binding,18,0.484001076,4.56E-05,"CDKN1B, TFRC, ST13, FGF1, NR3C1, DNAJA1, FKBP1A, BAG6, STIP1, DNAJC2, DNAJA3, DNAJC10, NUP62, RPS3, CDK1, BAX, MVD, PPID",3206,35,17446,2.798574102,0.096058614,0.001929278,0.001850053
GOTERM_MF_DIRECT,GO:1990446~U1 snRNP binding,8,0.215111589,4.72E-05,"SNRPD2, SNRPD1, SNRNP70, SNRPG, SNRPE, SNRPD3, SNRPC, SNRPB",3206,8,17446,5.441671865,0.099267671,0.001929278,0.001850053
GOTERM_MF_DIRECT,GO:0003857~3-hydroxyacyl-CoA dehydrogenase activity,8,0.215111589,4.72E-05,"HADHB, HADHA, EHHADH, HSD17B4, CRYL1, H2-KE6, HADH, HSD17B10",3206,8,17446,5.441671865,0.099267671,0.001929278,0.001850053
GOTERM_MF_DIRECT,GO:0030235~nitric-oxide synthase regulator activity,8,0.215111589,4.72E-05,"HSP90AA1, HSP90AB1, AKT1, CALM3, DYNLL1, CALM1, CALM2, EGFR",3206,8,17446,5.441671865,0.099267671,0.001929278,0.001850053
GOTERM_MF_DIRECT,GO:0000980~RNA polymerase II distal enhancer sequence-specific DNA binding,29,0.779779511,4.79E-05,"ATF2, SMARCD2, SMARCB1, HDAC1, CHD4, BACH1, ACTB, RBBP4, RUVBL2, NKX2-2, SMARCE1, MBD3, JUN, SMARCC1, SMARCC2, H3F3B, CDX2, H2AFZ, CDX1, NONO, H3F3A, MBD2, NFKB1, NR2F6, SFPQ, HNRNPC, TCF3, NFE2L1, NFE2L2",3206,73,17446,2.161760056,0.100676845,0.001929278,0.001850053
GOTERM_MF_DIRECT,GO:0051117~ATPase binding,33,0.887335305,4.93E-05,"UFD1L, RALA, UBXN1, TAF9, DERL1, TOR1AIP2, PIK3R1, FBL, RUVBL2, RAC1, ATP6V1E1, RAB6A, ACTR3, RAB4A, ATP6V1G1, NOP58, SDF2L1, S100A1, PIH1D1, ATPIF1, UBE4B, ATP1B3, ATP1B1, SVIP, ATOX1, HNRNPK, NHP2L1, ARPC2, FXYD3, DNAJC10, ALDOB, EZR, VIMP",3206,88,17446,2.040626949,0.103591608,0.001952794,0.001872603
GOTERM_MF_DIRECT,GO:0003730~mRNA 3'-UTR binding,23,0.618445819,7.63E-05,"RNF20, RBM14, CIRBP, HNRNPR, PUM1, YBX3, ELAVL1, ZFP36L2, ZFP36L1, PUM2, HNRNPL, ZFP36, LARP1, HNRNPK, KHSRP, PCBP1, HNRNPA2B1, SERBP1, RNPS1, IGF2BP2, HNRNPC, PABPC1, TARDBP",3206,53,17446,2.361480243,0.15564988,0.002968098,0.002846213
GOTERM_MF_DIRECT,"GO:0046961~proton-transporting ATPase activity, rotational mechanism",14,0.376445281,8.66E-05,"ATP6V1A, ATP6V0B, ATP6AP1, ATP5A1, ATP5C1, ATP5B, ATP5E, ATP5D, ATP6V1H, ATP6V0D1, ATP6V1E1, ATP6V1C1, ATP6V1F, ATP6V0E",3206,24,17446,3.174308588,0.174557279,0.003251307,0.003117792
GOTERM_MF_DIRECT,GO:0016209~antioxidant activity,14,0.376445281,8.66E-05,"SRXN1, APOA4, SEPW1, FAM213A, PRDX6, SOD1, FABP1, PRDX3, PRDX2, PRDX5, PRDX4, PRDX1, CAT, VIMP",3206,24,17446,3.174308588,0.174557279,0.003251307,0.003117792
GOTERM_MF_DIRECT,GO:0005525~GTP binding,101,2.715783813,9.61E-05,"RAB3B, RAB3C, RAB3D, GIMAP1, RAB43, TUBB5, NUDT16, TGM2, RAB2A, GTPBP1, GTPBP4, TUBA4A, TUFM, EEF1A1, RRAGD, SUCLG2, SUCLG1, FKBP4, ARL8B, RASL12, SAR1A, ARL3, AGAP1, AK3, AK4, GSPT1, RAP1B, RAP1A, RRAS, EIF2S3X, RAB6A, PCK2, RAB4A, EIF2B2, RAB4B, RAB27A, RAB27B, EEF2, GNAO1, EHD1, GLUD1, EIF5, GNL3L, GNAQ, GNAS, SRPRB, RAB5A, RAB9, ARF3, ARF4, ARF1, HSP90AB1, SRPR, OLA1, GMPPB, SEPT9, TUBA1C, TUBA1B, TUBA1A, ANXA6, RAC1, EIF2B1, ARL5A, RAB8A, EIF5B, HSP90AA1, RHOG, RHOC, RHOA, DNM1, DNM2, RAB33B, GNL3, NME1, ARL4A, RHOU, ARF5, ARF6, GUCY2C, RALA, TUBAL3, RAB1B, GNAI3, GNAI2, GNA13, CDC42, RAB25, GNA11, RAB24, ADSS, GCH1, TUBB4B, RAB11A, RAB11B, RAB10, RAB14, RAB15, TSR1, KRAS, RAB17, RAN",3206,383,17446,1.435010074,0.191756832,0.003548035,0.003402335
GOTERM_MF_DIRECT,GO:0031369~translation initiation factor binding,14,0.376445281,1.50E-04,"DDX3X, GCH1, CELF1, EIF3M, LARP1, RPS19, SYT11, RPS3A1, EIF4EBP1, POLR2G, EIF3F, EIF3C, RPS24, EIF3B",3206,25,17446,3.047336245,0.282917048,0.005451456,0.005227592
GOTERM_MF_DIRECT,GO:0004579~dolichyl-diphosphooligosaccharide-protein glycotransferase activity,8,0.215111589,1.78E-04,"KRTCAP2, RPN2, DAD1, RPN1, STT3A, MAGT1, STT3B, DDOST",3206,9,17446,4.837041658,0.326470393,0.006272827,0.006015233
GOTERM_MF_DIRECT,GO:0001055~RNA polymerase II activity,8,0.215111589,1.78E-04,"POLR2B, POLR2C, POLR2E, POLR2F, POLR2H, POLR2J, POLR2K, POLR2L",3206,9,17446,4.837041658,0.326470393,0.006272827,0.006015233
GOTERM_MF_DIRECT,GO:0070180~large ribosomal subunit rRNA binding,10,0.268889486,1.93E-04,"RPLP1, RPL12, RPL23, RPL37A, RPLP0, MRTO4, RPLP2, RPL23A, RPL17, RPL19",3206,14,17446,3.886908475,0.347604358,0.006672858,0.006398838
GOTERM_MF_DIRECT,GO:0000979~RNA polymerase II core promoter sequence-specific DNA binding,26,0.699112665,2.00E-04,"WBP2, GATA6, GATA3, HSF2, MYC, RUVBL2, NSD1, HNF4A, EP300, STAT6, SMYD3, EGR1, TCF7L2, H2AFY, H3F3B, H2AFZ, H3F3A, PAX6, FOS, SMAD5, CDK9, SP1, TRP53, IRF7, ZFPM1, TAF1",3206,67,17446,2.11169356,0.357445961,0.006804003,0.006524597
GOTERM_MF_DIRECT,GO:0015078~hydrogen ion transmembrane transporter activity,16,0.430223178,2.11E-04,"SLC36A1, SLC46A1, ATP6V0B, SLC11A2, ATP5K, ATP5J, ATP5G3, ATP5H, ATP5G2, ATP5F1, ATP5G1, ATP5L, ATP5D, ATP6V0D1, ATP6V1C1, ATP6V0E",3206,32,17446,2.720835933,0.373156044,0.006970275,0.006684041
GOTERM_MF_DIRECT,GO:0061631~ubiquitin conjugating enzyme activity,16,0.430223178,2.11E-04,"UBE2B, UBE2C, UBE2D3, UBE2G1, UBE2D2A, UBE2L3, UBE2W, CDC34, UBE2Q1, UBE2R2, UBE2S, UBE2N, UBE2V2, UBE2V1, UBE2K, TAF1",3206,32,17446,2.720835933,0.373156044,0.006970275,0.006684041
GOTERM_MF_DIRECT,GO:0016301~kinase activity,161,4.329120731,2.24E-04,"PANK3, ZMYND8, ARAF, TESK1, MYLK, IGF1R, RPS6KA4, SLK, CCND1, PLAU, STK16, RPS6KA1, PDK3, AKT1, PIM3, PIM2, PIP4K2C, PRKACA, SEPHS2, PRKACB, EPHB4, PDK2, EPHB3, MAP2K3, PRKCI, MAP2K2, PRKCD, CASK, PRKCA, CSNK1D, DGKZ, ERN2, PRKAR1A, MAPKAPK2, CSNK2B, CMPK1, IDNK, ULK1, AURKAIP1, PI4K2A, GNE, PFKFB2, PFKFB4, PKDCC, AK2, AK3, AK4, PIK3R1, PRKCZ, IRAK1, GRK4, PRKAR2A, STK38, PMVK, PACSIN2, ABL2, PIP5K1B, IP6K1, MARK2, NADK, CDK18, CHKB, CHKA, PLK1, CLK2, CDK9, CLK1, ICK, CDK8, STK24, CDK4, WNK1, CDK1, ALDH18A1, FGFR3, MAP3K11, GALK2, GALK1, DDR1, GSK3B, GSK3A, SMG1, MAST3, PRKCSH, MAST2, AKAP8L, ADK, PRKAG2, PIK3C2A, DUSP16, HK2, KHK, GUK1, RFK, PBK, PRKG2, TK1, JAK1, CAMK1D, SPHK2, ITPK1, MINK1, NME2, HUNK, BAZ1B, TGFBR1, NME1, PKM, HKDC1, KIT, CKS2, FAM20B, PICK1, STRAP, PIK3C3, CRK, CAMK2B, PRPS2, PDXK, DTYMK, MVK, ROCK1, SRC, ROCK2, SGMS2, EGFR, PAPSS2, PAPSS1, CKMT1, PAK1, ERBB2, MKNK2, PTK2B, MAPK1, CSK, CKB, PAK3, PAK2, MAPK4, MAP4K4, MAPK3, MAP3K1, PKLR, RIOK3, RYK, CSNK1A1, LIMK2, MAPK14, HIPK1, CDK11B, MAPK13, BCKDK, SNRK, PFKL, TAOK3, ETNK1, STK17B, PKN2, PFKP, FRK, TAF1",3206,674,17446,1.299865238,0.391458988,0.00730346,0.007003544
GOTERM_MF_DIRECT,GO:0001948~glycoprotein binding,29,0.779779511,2.36E-04,"ITGB1, HSP90AB1, TFRC, EGFR, ERLEC1, SDCBP, OS9, CDH1, LMAN2, ERBB2, LDLR, B2M, CTSA, HSP90AA1, HSPA5, ITGA3, CSNK1A1, EDEM1, EDEM2, CSNK1D, IGF2R, ACE2, RAB14, DNAJC5, CANX, DNAJA2, SDC1, VIM, CALR",3206,79,17446,1.997575748,0.406676169,0.007564543,0.007253905
GOTERM_MF_DIRECT,GO:0046982~protein heterodimerization activity,127,3.414896478,2.56E-04,"ATF2, DGKD, GABPB2, H2-K1, SMC3, NR3C1, SMC4, CREB3L3, CAPNS1, SCP2, PPP2R1A, MYC, SOX9, PDK2, SOX4, TPD52, HES6, ABCG8, BNIP3L, ABCG5, CYBA, SLC51A, FOXP4, FOXP1, RBP4, CLNS1A, RRAGD, SUCLG2, SUCLG1, ATF6, H2-D1, ATF3, ATF4, PEF1, CUL3, MTTP, PDGFA, PIK3R1, OAZ1, ADIPOR2, HIF1A, NEUROD1, SDCBP, SNX1, SNX2, IRAK1, MCL1, FZD1, GSTM2, JUN, XBP1, GSTM1, HOMER2, PBX1, NFKB1, MLXIPL, GCLC, LSM7, LSM6, TRP53, BHLHE40, UBA2, TCF3, GCLM, SAE1, BCL2L2, NFE2L2, H2-AB1, ITGB1, YWHAE, TOP2A, THRA, HEXB, HEXA, BHLHE41, PPP3CA, MLX, HMG20B, BOK, YWHAH, PRMT5, H2AFY, ITGA3, H2AFZ, H2AFX, H2AFV, FOS, ADRA2A, TGFBR1, QTRT1, MICU2, PPARA, PAFAH1B3, CEBPA, GTF2A2, CEBPG, H2-Q4, SRI, CLCN3, CENPA, H2-Q1, EGFR, HSPD1, PPP2CA, CHRAC1, TTR, RXRA, ERBB2, CTNNA1, BAK1, MAPK4, NPM1, BAD, BNIP3, LIMK2, SGTA, HIP1R, USF2, H2-AA, VEGFA, HIST3H2A, TEF, VAPA, CTNNB1, BAX, P4HB, TAF1",3206,514,17446,1.344537601,0.43311406,0.008107493,0.007774558
GOTERM_MF_DIRECT,GO:0043531~ADP binding,17,0.457112127,2.81E-04,"PRPS2, HSPA8, VCP, ATP5A1, PRKAG1, PRKAG2, ATP1A1, GLUD1, GCLC, PKM, CYB5R3, RUVBL2, CHORDC1, MYO18A, LONP1, PGK1, MYH9",3206,36,17446,2.569678381,0.463252987,0.00876255,0.008402716
GOTERM_MF_DIRECT,GO:0030331~estrogen receptor binding,19,0.510890024,2.97E-04,"DDX17, DDX5, DNMT1, PCNA, PARP1, SRC, FUS, TAF10, TRIP4, DDX54, ARRB1, PIK3R1, RNF4, HSD17B10, NCOR1, CNOT1, NSD1, CTNNB1, PPID",3206,43,17446,2.404459661,0.482512895,0.009148233,0.008772561
GOTERM_MF_DIRECT,GO:0004175~endopeptidase activity,37,0.9948911,3.14E-04,"PCSK1, PSMD14, KLK1, ECE1, FURIN, PSEN1, PCSK5, PSMA7, PSMB10, PSMB6, APH1A, PSMB7, PSMB4, PSMB5, PSMB2, PSMB3, CASP6, PSMD2, PSMB1, CASP1, PSMD1, RCE1, CTSD, CTSB, MME, PSMB8, PSMA5, BACE1, PSMA6, TMEM59, ACE2, PSMA3, PSMA4, PSMA1, CPS1, PSMA2, TPP1",3206,112,17446,1.79769517,0.50168217,0.009539832,0.009148079
GOTERM_MF_DIRECT,GO:0034236~protein kinase A catalytic subunit binding,10,0.268889486,4.03E-04,"GSK3B, GSK3A, AKAP11, PRKAR1A, KCNQ1, PRKAR2A, CSK, SOX9, EZR, PJA2",3206,15,17446,3.627781244,0.590792879,0.012072348,0.011576597
GOTERM_MF_DIRECT,GO:0017025~TBP-class protein binding,12,0.322667384,4.51E-04,"PSMC5, GTF2A2, PSMC6, CAND1, THRA, PSMC3, NACA, PSMC4, HNRNPF, PSMC1, RNF4, TAF1",3206,21,17446,3.10952678,0.631971886,0.01332494,0.012777752
GOTERM_MF_DIRECT,GO:0016874~ligase activity,93,2.500672224,4.80E-04,"VARS, PRPF19, EPRS, AACS, NARS, TRIM8, RNF114, TRIM28, RARS, TRIM2, TRIM25, TRIM27, GLUL, ATG3, RNF43, WARS, LIG1, CAD, MSL2, ACSL6, SARS, ZFP91, ACSL5, UBE4B, ACSL3, PJA2, RC3H2, RBX1, LARS2, RNF167, RNF126, KARS, RNF128, MTHFD1, PCCB, PELI1, SUCLG2, SUCLG1, GARS, RBCK1, SLC27A2, GART, SLC27A4, ACSS2, UHRF1, MYCBP2, UBR4, UBR3, TARS, RNF6, RCHY1, RNF4, RNF5, NEURL1B, HECTD1, UBR7, HLTF, RBBP6, ACSS1, ADSS, RNF20, UBE2I, TRIM41, GSS, AMFR, IRF2BP1, ASNS, WWP2, MARCH6, PAICS, MARCH5, CNOT4, GCLC, SUCLA2, RNF103, CPS1, TRIM39, RFWD2, NEURL3, RNF149, NEDD4, MARS, UBA2, RNF181, UBA1, IARS, SAE1, FARSA, TRIM31, UBE2M, RNF220, FARSB, RNF187",3206,362,17446,1.397998573,0.654709859,0.013988357,0.013413925
GOTERM_MF_DIRECT,GO:0003690~double-stranded DNA binding,42,1.129335843,5.67E-04,"FOXA1, ZFP148, DNMT1, CEBPG, GATA6, HMGB2, NUCKS1, HMGB1, NR3C1, PURB, NEUROD1, RXRA, MYC, SAFB2, STRA13, JUNB, EGR1, JUN, JUND, RFC1, CDX2, PAX6, FOS, SAFB, KLF4, USF2, NFKB1, KLF6, HNRNPK, SLTM, TEF, SP1, NFIB, FEV, NFIC, FOSB, CTNNB1, RBCK1, TARDBP, LSM14A, CGGBP1, FOXA2",3206,136,17446,1.680516311,0.715494167,0.016320066,0.015649883
GOTERM_MF_DIRECT,GO:0043022~ribosome binding,22,0.59155687,5.83E-04,"EIF5A, YTHDF1, NAA10, HSPA5, RPN2, OLA1, RPSA, EEF2, EIF2S1, PTMS, LETM1, BAG6, SEC61A1, SPCS1, EIF6, EIF3K, DENR, SEC61B, EIF3C, RPS21, ABCF1, EIF2A",3206,56,17446,2.137799661,0.725323801,0.016561355,0.015881263
GOTERM_MF_DIRECT,GO:0004129~cytochrome-c oxidase activity,14,0.376445281,6.24E-04,"COX8A, COX7B, NDUFA4, COX4I1, COX7A2, AA467197, COX6C, COX5B, COX6A1, COX7A1, COX7C, COX5A, COX6B1, COX7A2L",3206,28,17446,2.720835933,0.748951115,0.017270959,0.016561727
GOTERM_MF_DIRECT,"GO:0016627~oxidoreductase activity, acting on the CH-CH group of donors",14,0.376445281,6.24E-04,"ACADVL, SRD5A1, TECR, SDHC, SDHA, ACADSB, TM7SF2, ACADL, ACOX1, DPYD, ACADM, ACAD11, ACADS, LBR",3206,28,17446,2.720835933,0.748951115,0.017270959,0.016561727
GOTERM_MF_DIRECT,GO:0016829~lyase activity,42,1.129335843,9.18E-04,"GUCY2C, TSEN34, DDC, ECHS1, PDXDC1, GLO1, ODC1, HSD17B4, ADCY1, SDSL, PTS, ADCY6, ALAD, POLB, HMGCL, GMDS, UROD, DDT, RPS3, ASL, CAR9, PCBD1, GLUL, PCK2, ADSL, FAHD1, PTGES2, UROS, PAICS, FH1, DERA, PISD, HADHA, FASN, CTH, EHHADH, ALDOC, MVD, ACO1, ALDOB, ACO2, PAM",3206,139,17446,1.644246175,0.869366537,0.025116363,0.02408496
GOTERM_MF_DIRECT,GO:0030515~snoRNA binding,12,0.322667384,0.001204766,"NOP56, NOP58, NHP2L1, IMP3, GAR1, NHP2, DDX21, IMP4, NUDT16, NUDT16L1, NOP10, NUDT4",3206,23,17446,2.839133147,0.930842675,0.032558071,0.031221074
GOTERM_MF_DIRECT,GO:0044325~ion channel binding,37,0.9948911,0.001310821,"YWHAE, SNAP25, HSP90AB1, KCNE3, USP10, PRKCSH, SRC, CIB1, ARRB1, SLC8A1, HERPUD1, PYCARD, PPP2CA, SUMO1, YWHAQ, TSPO, BAK1, S100A10, YWHAH, PRNP, HSP90AA1, ACTN1, ACTN4, EPN1, CHERP, FKBP1A, DLG1, KCNQ1, CTNNB1, RANGRF, CALM3, VDAC1, HAP1, CALM1, PHPT1, CALM2, GRINA",3206,120,17446,1.677848825,0.945343329,0.034645609,0.033222888
GOTERM_MF_DIRECT,GO:0015035~protein disulfide oxidoreductase activity,11,0.295778435,0.001313281,"TXN1, GSTK1, GLRX3, PTGES2, GLRX5, TXNL1, DNAJC10, GLRX, GFER, TXN2, ERO1L",3206,20,17446,2.992919526,0.94564093,0.034645609,0.033222888
GOTERM_MF_DIRECT,GO:0016208~AMP binding,9,0.242000538,0.001340057,"PRPS2, CYB5R3, ACSS2, PRKAG1, PRKAG2, AKAP7, ACSS1, FBP1, APRT",3206,14,17446,3.498217628,0.948776511,0.034936066,0.033501417
GOTERM_MF_DIRECT,GO:0008565~protein transporter activity,25,0.672223716,0.001373048,"USO1, TIMM13, AP2A2, IPO5, RAP1A, XPO1, AP1G2, AP1G1, XPO6, KPNA6, AP2S1, AP1S1, VPS35, AP3S1, KPNA2, SEC62, TNPO2, RAB4A, AP3D1, AP1B1, AP2B1, RANGRF, RAMP1, KPNB1, TOMM5",3206,71,17446,1.916081643,0.952392555,0.035379946,0.033927069
GOTERM_MF_DIRECT,GO:0016887~ATPase activity,55,1.478892175,0.001607945,"ABCD4, EIF4A2, EIF4A1, DDX3X, ABCD3, DQX1, OLA1, ATP5C1, RUVBL2, LONP1, KIF1B, KIF21A, ABCC3, ABCG8, TOR3A, ABCG5, HSP90AA1, RALBP1, ATP6V1G1, KIF24, WRNIP1, ATP1B1, ATP5F1, ATP5J2, DDX39B, PEX6, PICK1, MYH9, CFTR, VCP, ATP5A1, ATP5K, ATP5J, ABCB9, ATP5H, ATP5O, ATP5L, ATP5B, ASNA1, ATP5E, HLTF, ATP5D, ABCB1A, ABCF1, DDX39, DYNC1H1, HSPA8, HSPA5, ATP13A1, SMARCA5, TOR1B, SMARCA2, PSMC5, MYO5B, ATP13A3",3206,200,17446,1.496459763,0.971733407,0.0409564,0.039274527
GOTERM_MF_DIRECT,GO:0000287~magnesium ion binding,55,1.478892175,0.002040551,"TOP2A, ARF1, MAST3, MAST2, PTEN, COMT, RPS6KA4, IMPA1, RPS6KA1, IDH3B, PAPOLA, PGM2, NUDT16, GLUL, PRKACB, IDH3A, ITPK1, YDJC, NME1, ERN2, PPM1A, PKM, PPA1, ILVBL, MTHFD2, PGP, TKT, DCTPP1, PRPS2, PDXK, NT5C3, PRPSAP1, HMGCL, STK38, ABL2, BPNT1, ADSS, MARK2, PRPS1L3, ATP9A, DUT, PKLR, ATP8B1, IDH3G, CSNK1A1, GSS, IDH1, IDH2, HPRT, ICK, SNRK, GCLC, WNK1, ALPI, FARSB",3206,202,17446,1.48164333,0.989181313,0.051384779,0.049274664
GOTERM_MF_DIRECT,GO:0001054~RNA polymerase I activity,8,0.215111589,0.002333945,"ZNRD1, POLR1C, POLR1D, POLR2E, POLR2F, POLR2H, POLR2K, POLR2L",3206,12,17446,3.627781244,0.99436111,0.056788362,0.054456349
GOTERM_MF_DIRECT,"GO:0016651~oxidoreductase activity, acting on NAD(P)H",8,0.215111589,0.002333945,"NDUFS8, NDUFA5, AIFM1, NDUFS4, NDUFS3, NDUFS2, NDUFS1, NDUFV1",3206,12,17446,3.627781244,0.99436111,0.056788362,0.054456349
GOTERM_MF_DIRECT,GO:0044548~S100 protein binding,8,0.215111589,0.002333945,"ANXA2, AHNAK, S100A1, S100A6, ATP2A2, IQGAP1, FGF1, EZR",3206,12,17446,3.627781244,0.99436111,0.056788362,0.054456349
GOTERM_MF_DIRECT,GO:0004177~aminopeptidase activity,13,0.349556332,0.00235764,"ENPEP, CPQ, PEPD, DPP3, DPP4, NPEPPS, DNPEP, XPNPEP1, CTSL, ANPEP, LTA4H, LAP3, METAP2",3206,28,17446,2.526490509,0.994650209,0.056788362,0.054456349
GOTERM_MF_DIRECT,GO:0043295~glutathione binding,9,0.242000538,0.002410821,"GSTM4, GSTM2, GSTA4, PTGES2, GSS, GSTP1, GSR, MGST1, GSTM7",3206,15,17446,3.265003119,0.995246287,0.057444938,0.055085962
GOTERM_MF_DIRECT,GO:0004386~helicase activity,38,1.021780048,0.002719336,"EIF4A2, DDX6, EIF4A1, DDX5, DDX3X, DDX27, MCM7, DDX46, DDX24, DHX9, DQX1, DDX1, CHD8, CHD7, DDX21, CHD4, DHX32, RUVBL2, G3BP1, DHX36, HLTF, DHX15, EP400, DDX17, DDX39, ATRX, SMARCA5, DDX54, SMARCA2, GTF2F2, MOV10, DDX39B, MCM3, MCM5, MCM6, SNRNP200, SKIV2L2, MCM2",3206,129,17446,1.602973108,0.997604723,0.064106896,0.061474347
GOTERM_MF_DIRECT,GO:0042826~histone deacetylase binding,34,0.914224254,0.002807681,"TOP2A, YWHAE, CEBPA, DNMT1, HSP90AB1, YWHAB, HDAC1, GMNN, AKAP8L, BHLHE41, PHB, HIF1A, YY1, NIPBL, ZNHIT1, CCND1, RBBP4, DHX36, HES1, CIR1, RAC1, KPNA2, WDTC1, HSP90AA1, XBP1, CBX5, PARP1, KLF4, SFPQ, NCOR1, SP1, HNRNPD, PKN2, INSM1",3206,112,17446,1.651936102,0.998031674,0.065492851,0.062803388
GOTERM_MF_DIRECT,GO:0003697~single-stranded DNA binding,27,0.726001613,0.003022835,"MCM7, PRIM1, NUCKS1, YBX1, YBX3, PURB, PTBP1, PCBP1, LONP1, POLR2G, CNBP, ALYREF, RPA2, TSN, LRPPRC, NME1, HNRNPK, ERCC4, RPA3, NCL, SUB1, MCM6, SSBP1, SSBP2, NOL12, SSBP3, SSBP4",3206,83,17446,1.770182414,0.998779808,0.069777104,0.066911708
GOTERM_MF_DIRECT,GO:0008379~thioredoxin peroxidase activity,6,0.161333692,0.003148087,"SEP15, PRDX3, PRDX2, PRDX5, FAM213B, PRDX1",3206,7,17446,4.66429017,0.999076339,0.070466276,0.067572579
GOTERM_MF_DIRECT,GO:0008121~ubiquinol-cytochrome-c reductase activity,6,0.161333692,0.003148087,"UQCRB, UQCRQ, UQCRFS1, UQCR11, UQCR10, UQCRH",3206,7,17446,4.66429017,0.999076339,0.070466276,0.067572579
GOTERM_MF_DIRECT,GO:0008097~5S rRNA binding,6,0.161333692,0.003148087,"RPL4, RPL5, RPL3, MRPL18, EEF2, RPL7",3206,7,17446,4.66429017,0.999076339,0.070466276,0.067572579
GOTERM_MF_DIRECT,GO:0004004~ATP-dependent RNA helicase activity,22,0.59155687,0.003226185,"DDX17, EIF4A2, DDX39, EIF4A1, DDX6, DDX5, DDX3X, DDX27, DDX46, DDX24, DHX9, DQX1, DDX1, EIF4A3, DDX21, DDX54, DDX19B, DHX32, DDX39B, DHX36, DHX15, SNRNP200",3206,63,17446,1.900266366,0.999223554,0.071492262,0.068556434
GOTERM_MF_DIRECT,GO:0051879~Hsp90 protein binding,14,0.376445281,0.003840315,"PTGES3, NR3C1, HIF1A, USP19, NASP, ARHGDIA, CDC37, CHORDC1, ERBB2, NUP62, RPS3, ULK1, KPNB1, PPID",3206,33,17446,2.308588064,0.999801857,0.084258795,0.08079871
GOTERM_MF_DIRECT,GO:0070034~telomerase RNA binding,9,0.242000538,0.004050277,"TEP1, DKC1, GAR1, NHP2, HNRNPU, SNRPD3, HNRNPC, NOP10, SNRPB",3206,16,17446,3.060940424,0.999875803,0.087667371,0.084067312
GOTERM_MF_DIRECT,GO:0051920~peroxiredoxin activity,7,0.18822264,0.004074792,"PRDX3, PRDX2, PRDX5, PRDX4, PRDX1, PARK7, PRDX6",3206,10,17446,3.809170306,0.999882396,0.087667371,0.084067312
GOTERM_MF_DIRECT,GO:0001102~RNA polymerase II activating transcription factor binding,15,0.40333423,0.005573023,"ATF2, BEX2, JUN, SETD3, LDB1, CITED2, BHLHE41, NEUROD1, NCOR1, HNF4A, BHLHE40, CTNNB1, EP300, ZFPM1, NFE2L2",3206,38,17446,2.148028368,0.999995816,0.118485199,0.113619606
GOTERM_MF_DIRECT,GO:0003746~translation elongation factor activity,12,0.322667384,0.005667613,"EIF5A, EEF1G, EEF1A1, EEF1B2, TSFM, ELOF1, EEF1D, TCEA1, EEF2, GTPBP1, PTMS, TUFM",3206,27,17446,2.418520829,0.999996612,0.118485199,0.113619606
GOTERM_MF_DIRECT,"GO:0051537~2 iron, 2 sulfur cluster binding",12,0.322667384,0.005667613,"ISCA1, GLRX5, FDX1, CISD1, UQCRFS1, CISD2, NDUFS1, CIAPIN1, NDUFV2, SDHB, XDH, CISD3",3206,27,17446,2.418520829,0.999996612,0.118485199,0.113619606
GOTERM_MF_DIRECT,GO:0002039~p53 binding,23,0.618445819,0.005821086,"RNF20, GSK3B, NPM1, USP7, SMARCB1, KDM1A, USP10, EHMT2, CHD8, PTGES3, SETD7, TAF9, EHMT1, PTTG1IP, YBX1, RCHY1, EEF2, HSPD1, TEP1, TRP53, SMYD2, EP300, TAF1",3206,70,17446,1.787977899,0.999997593,0.119440067,0.114535262
GOTERM_MF_DIRECT,GO:0003725~double-stranded RNA binding,23,0.618445819,0.005821086,"EIF4A1, MBNL1, HSP90AB1, TFRC, STRBP, ACTN1, DDX1, CLTC, DDX21, SLC3A2, HMGB1, TUBB4B, ELAVL1, TARBP2, HSPD1, YRDC, ILF3, TUBA1B, DHX36, DHX15, VIM, LSM14A, SIDT2",3206,70,17446,1.787977899,0.999997593,0.119440067,0.114535262
GOTERM_MF_DIRECT,GO:0008143~poly(A) binding,9,0.242000538,0.006430274,"SYNCRIP, KHDRBS1, DDX3X, PABPN1, DDX1, PABPC4, EIF4A3, PABPC1, PAIP2",3206,17,17446,2.880885105,0.999999381,0.130729232,0.125360839
GOTERM_MF_DIRECT,GO:0003899~DNA-directed RNA polymerase activity,14,0.376445281,0.006887951,"POLR2M, PRIM1, ZNRD1, POLR2B, POLR2C, POLR1C, POLR1D, POLR2E, POLR2F, POLR2G, POLR2H, POLR2J, POLR2K, POLR2L",3206,35,17446,2.176668746,0.999999777,0.138760905,0.13306269
GOTERM_MF_DIRECT,GO:0030957~Tat protein binding,6,0.161333692,0.007124694,"DNAJA1, NPM1, GABARAPL1, SMARCB1, DLL1, ACTB",3206,8,17446,4.081253899,0.999999869,0.141995994,0.136164931
GOTERM_MF_DIRECT,GO:0001671~ATPase activator activity,8,0.215111589,0.007176693,"RAB4A, DNAJB6, DNAJC10, TOR1AIP2, AHSA1, ATP1B3, RAB6A, ATP1B1",3206,14,17446,3.10952678,0.999999883,0.141995994,0.136164931
GOTERM_MF_DIRECT,"GO:0005547~phosphatidylinositol-3,4,5-trisphosphate binding",15,0.40333423,0.007249964,"NPM1, MYO10, GBF1, FAM21, INPPL1, HIP1R, DAPP1, IQGAP1, COMMD1, IQGAP2, ADAP1, MYO1B, PARD3, AKT1, OGT",3206,39,17446,2.092950717,0.999999901,0.14217628,0.136337814
GOTERM_MF_DIRECT,GO:0042301~phosphate ion binding,7,0.18822264,0.00757785,"PNP, G6PC, PNP2, MTHFD2, GNG12, PTPRF, OTC",3206,11,17446,3.462882096,0.999999952,0.147302768,0.141253782
GOTERM_MF_DIRECT,GO:0004842~ubiquitin-protein transferase activity,78,2.097337994,0.009716143,"RNF10, WDSUB1, UBE2D3, FBXO25, KEAP1, TNFAIP1, PRPF19, UBE2D2A, BACH1, UBE2L3, TRIM8, HERC2, RNF114, TRIM28, TRIM2, FBXO3, TRIM25, TRIM27, SKP1A, ZYG11B, RNF43, ZYG11A, WSB1, FBXW11, ZFP91, PJA2, RC3H2, RBX1, NAIP2, RNF167, NAIP5, CDC34, TRAF4, UBE2R2, PELI1, BIRC5, RBCK1, NAIP1, UHRF1, CUL3, UBR4, UBR3, RNF6, RCHY1, RNF4, RNF5, ANAPC11, HECTD1, RMND5A, HECTD3, RBBP6, TCEB1, RNF20, ANKIB1, MAP3K1, UBE2I, UBE2B, UBE2C, AMFR, KLHL2, UBE2G1, WWP2, FBXO32, MARCH6, MARCH5, CNOT4, UBE2W, RNF103, UBE2S, NEDD4, KBTBD2, UBE2N, RNF181, UBA1, UBE2K, UBE2M, RNF220, RNF187",3206,326,17446,1.301995109,1,0.185955094,0.178318851
GOTERM_MF_DIRECT,GO:0008327~methyl-CpG binding,9,0.242000538,0.009734111,"MBD3, PRMT5, DNMT1, CHTOP, UHRF1, PRMT1, MBD2, ERH, ZBTB4",3206,18,17446,2.720835933,1,0.185955094,0.178318851
GOTERM_MF_DIRECT,"GO:0001077~transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding",66,1.77467061,0.010851235,"FOXA1, ATF2, EHF, ONECUT2, NUCKS1, YBX1, NR3C1, HNF4A, CREB3L1, MYC, STK16, MYB, SOX9, JUNB, SOX4, SREBF1, KLF13, PAX6, FOS, POU3F2, ETV6, ELF1, PLSCR1, ELF3, ZFP292, IRF1, PREB, PPARA, ATF4, NFAT5, CEBPA, CEBPG, GATA3, HIF1A, NEUROD1, HLTF, CAMTA1, STAT6, ZBTB7B, ATOH1, ESRRA, TCF7L2, EGR1, JUN, JUND, STAT3, NFATC3, KLF4, PBX1, CTCFL, NFKB2, HNRNPK, KLF5, TEF, NFIA, SP1, NFIB, TRP53, NFIC, FOSB, CEBPZ, TCF3, SSBP2, SSBP3, SSBP4, FOXA2",3206,270,17446,1.330186456,1,0.203782507,0.195414182
GOTERM_MF_DIRECT,GO:0008289~lipid binding,66,1.77467061,0.010851235,"FAAH, PITPNB, PITPNA, PEBP1, DBI, ATP5G3, FNBP1L, NR3C1, ATP5G2, CLINT1, ATP5G1, AP2A2, BAIAP2L2, SCP2, MCF2L, ANXA6, FFAR2, SH3GL1, SH3GLB1, STARD4, STARD5, STARD7, ACOT11, GOLPH3L, APOA1, APOA4, EPN1, RBP2, PARD3, PPARA, MGLL, GRB7, STOML2, VCP, MTTP, NOXO1, SNX3, SEC14L2, PGRMC1, SNX1, PGRMC2, SNX2, PACSIN2, S100A13, MVB12A, APOB, MARK2, SNX5, SNX6, ACBD5, PLEKHA1, BAD, STARD10, APOC3, PLEKHA8, FABP1, FABP2, GOLPH3, FABP5, SNX17, APOC2, ALB, BAX, ESYT1, OGT, TECPR1",3206,270,17446,1.330186456,1,0.203782507,0.195414182
GOTERM_MF_DIRECT,GO:0023026~MHC class II protein complex binding,8,0.215111589,0.011346831,"YWHAE, CD74, HSPA8, HSP90AA1, PKM, HSP90AB1, CD81, ATP1B1",3206,15,17446,2.902224995,1,0.209538141,0.200933461
GOTERM_MF_DIRECT,GO:0017127~cholesterol transporter activity,8,0.215111589,0.011346831,"ABCG8, ABCG5, STARD4, STARD5, SCP2, APOA1, APOA4, APOB",3206,15,17446,2.902224995,1,0.209538141,0.200933461
GOTERM_MF_DIRECT,GO:0003988~acetyl-CoA C-acyltransferase activity,5,0.134444743,0.012432871,"HADHB, HADHA, ACAA2, SCP2, ACAA1A",3206,6,17446,4.534726554,1,0.220240269,0.211196107
GOTERM_MF_DIRECT,GO:0036402~proteasome-activating ATPase activity,5,0.134444743,0.012432871,"PSMC5, PSMC6, PSMC3, PSMC4, PSMC1",3206,6,17446,4.534726554,1,0.220240269,0.211196107
GOTERM_MF_DIRECT,GO:0050733~RS domain binding,5,0.134444743,0.012432871,"SON, SARNP, SRSF1, U2AF1, SRSF5",3206,6,17446,4.534726554,1,0.220240269,0.211196107
GOTERM_MF_DIRECT,GO:0030619~U1 snRNA binding,5,0.134444743,0.012432871,"ISG20, SNRNP70, SNRPC, PRPF8, SNRPA",3206,6,17446,4.534726554,1,0.220240269,0.211196107
GOTERM_MF_DIRECT,GO:0030620~U2 snRNA binding,5,0.134444743,0.012432871,"ISG20, SNRPA1, SNRPD3, PRPF8, SNRPB",3206,6,17446,4.534726554,1,0.220240269,0.211196107
GOTERM_MF_DIRECT,"GO:0016671~oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor",7,0.18822264,0.012821755,"TXN1, MSRA, TXNL1, DNAJC10, MSRB1, TXN2, ERO1L",3206,12,17446,3.174308588,1,0.220240269,0.211196107
GOTERM_MF_DIRECT,GO:1990381~ubiquitin-specific protease binding,7,0.18822264,0.012821755,"BAG6, VCP, AMFR, DERL1, PARK7, MARCH6, VIMP",3206,12,17446,3.174308588,1,0.220240269,0.211196107
GOTERM_MF_DIRECT,GO:0035925~mRNA 3'-UTR AU-rich region binding,7,0.18822264,0.012821755,"ZFP36, CPSF1, KHSRP, HNRNPD, ELAVL1, ZFP36L2, ZFP36L1",3206,12,17446,3.174308588,1,0.220240269,0.211196107
GOTERM_MF_DIRECT,GO:0036002~pre-mRNA binding,7,0.18822264,0.012821755,"PTBP1, RBM14, DDX5, TRA2B, LSM1, SRSF2, SRSF6",3206,12,17446,3.174308588,1,0.220240269,0.211196107
GOTERM_MF_DIRECT,GO:0000978~RNA polymerase II core promoter proximal region sequence-specific DNA binding,84,2.258671686,0.012967383,"EHF, GMEB2, SMARCB1, ONECUT2, CHD7, BHLHE41, CHD4, YBX1, CTCF, NR3C1, ETS2, ACTB, YY1, MYC, MYB, EP300, JUNB, TGIF1, SREBF1, SMARCC1, KLF13, SMARCC2, EED, H2AFZ, PAX6, FOS, FOXP4, POU3F2, SREBF2, ETV6, FOXP1, ELF1, ELF3, RFX6, SARNP, IRF1, TFAM, PPARA, ATF3, ATF4, NFAT5, CEBPA, ZFP148, SMARCD2, HDAC1, CEBPG, ASCL2, NEUROD1, RBBP4, HLTF, ZBTB7B, ZBTB7A, ATOH1, ESRRA, SMARCE1, MBD3, TCF7L2, JUN, JUND, MBD2, STAT3, NFATC3, USF2, PBX1, CTCFL, NFKB2, MLXIPL, HNRNPK, KLF5, TEF, NFIA, SP1, NFIB, NFIC, FOSB, CEBPZ, HDGF, HNRNPC, TCF3, INSM1, SSBP2, SSBP3, SSBP4, FOXA2",3206,359,17446,1.273260269,1,0.220240269,0.211196107
GOTERM_MF_DIRECT,GO:0005504~fatty acid binding,11,0.295778435,0.013019619,"FABP1, SH3GLB1, FABP2, FABP5, DGAT1, ACOX1, HNF4A, ARHGDIA, ALB, NME2, ADH5",3206,26,17446,2.302245789,1,0.220240269,0.211196107
GOTERM_MF_DIRECT,GO:0019869~chloride channel inhibitor activity,6,0.161333692,0.013618435,"VAMP8, WNK1, STX8, STX7, CFTR, VTI1B",3206,9,17446,3.627781244,1,0.225212335,0.215963995
GOTERM_MF_DIRECT,GO:0047372~acylglycerol lipase activity,6,0.161333692,0.013618435,"PNLIPRP2, LIPE, FAAH, ABHD16A, ABHD6, MGLL",3206,9,17446,3.627781244,1,0.225212335,0.215963995
GOTERM_MF_DIRECT,GO:0008430~selenium binding,6,0.161333692,0.013618435,"SEP15, SELENBP1, PRDX2, GPX4, GPX3, SEPP1",3206,9,17446,3.627781244,1,0.225212335,0.215963995
GOTERM_MF_DIRECT,"GO:0001205~transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding",13,0.349556332,0.014460134,"CDX1, BACH1, NFKB1, HCFC1, CUX1, FUBP1, SUB1, TCF3, TARDBP, NFE2L1, NFE2L2, NKX2-2, FOXA2",3206,34,17446,2.080639243,1,0.237360425,0.227613223
GOTERM_MF_DIRECT,GO:0008270~zinc ion binding,226,6.076902393,0.015291712,"CDA, TES, ZMYND8, EHMT2, EHMT1, ZDHHC3, RNF114, HERC2, TRIM28, ZMIZ2, ANPEP, CHORDC1, TRIM25, TRIM27, PGLYRP1, MECR, SCAF11, SLC11A2, PRKCA, UPB1, 4931406C07RIK, RC3H2, RNF126, RNF128, EWSR1, UQCRC1, RBCK1, UQCRC2, SF1, ZFP622, ENPEP, MYCBP2, GATA6, BAZ2A, GATA3, BAZ2B, ADH5, ANAPC11, MBTD1, ADH4, ADH1, MICAL1, HLTF, S100A13, AMZ2, LTA4H, VAT1, EGR1, TRIP4, MICAL2, NR2F6, RNF103, ZZZ3, RPS29, PAM, RNF220, ZCCHC11, ACY1, PHF20, ZFAND2B, HNF4G, LIMD1, PTMS, TRIM8, CSRP2, CSRP1, ADAMTSL5, HNF4A, ZMYM5, TRIM2, TK1, PARP1, MME, ZFR, ASH1L, PTGR1, BAZ1B, RNF167, PPARA, ZDHHC20, NR1I3, NR1I2, PRICKLE2, CRIP1, LIMA1, NEURL1B, RXRA, NSD1, MICALL2, ZSWIM8, SF3A3, PCGF6, ANKIB1, MAP3K1, GCH1, RNF145, MYBBP1A, ZDHHC9, RNF149, RFWD2, NBR1, ZYX, TCEA1, MSRB1, GDA, ZFAND3, ZFAND6, RORC, RORB, NR3C1, CNDP2, NPEPPS, FNTA, NRD1, PMPCB, EP300, CAR9, CAR8, SLC30A7, RNF43, RNF44, KDM2A, LMO7, MYT1, TIMM8A1, RBX1, LMX1A, S100A6, MATR3, SNRPC, UTRN, SRSF7, SQSTM1, ZFP330, ZCCHC7, DNMT1, GLO1, PXN, UBR4, UBR3, LPP, PHF21B, DPP3, ZMAT2, UBR7, MAN2A1, BPTF, ESRRA, ZFHX3, VDR, FUS, PHF12, MT2, MT1, MARCH6, MARCH5, ZZEF1, BSPRY, CNOT4, CPD, ALB, CPE, RNF181, ALPI, RNF186, RNF187, RERE, KDM5A, RNF10, DIDO1, RNPEPL1, THRA, USP33, FHL2, FHL3, CHD4, CHD3, ALAD, LASP1, ZNRD1, WHSC1, MMP7, ADH6A, CAD, MSL2, SORD, PJA2, TRAF4, MEP1B, BIRC5, ZMYND11, SMPDL3A, PAPPA2, PDXK, SEC23A, GALT, UHRF1, CXXC1, RNF6, RCHY1, SAMHD1, CXXC5, RNF4, RNF5, MLLT6, PDLIM1, DNPEP, RBBP6, PDLIM5, TRIM44, POLR2L, RNF20, TRIM41, CHURC1, USP22, AMFR, CNBP, LIMK2, SOD1, P2RX4, TRIM39, NEURL3, VPS41, SEC24D, TRIM31, SEC24C",3206,1075,17446,1.144016597,1,0.249164955,0.238933001
GOTERM_MF_DIRECT,GO:0030170~pyridoxal phosphate binding,18,0.484001076,0.016963866,"PDXK, DDC, OAT, ALAS1, PDXDC1, SHMT2, SHMT1, GOT2, GPT, SDSL, GCAT, PROSC, NFS1, SPTLC1, SPTLC2, MARC2, CTH, ALB",3206,55,17446,1.780910792,1,0.269432805,0.258368552
GOTERM_MF_DIRECT,GO:0050660~flavin adenine dinucleotide binding,22,0.59155687,0.016982408,"ACADVL, MAOB, KDM1A, MAOA, TXNRD1, GSR, DHCR24, ETFA, SDHA, ACADSB, GFER, FMO5, POR, CYB5R3, ACADL, AIFM1, ACOX1, ACADM, ACAD11, XDH, DLD, ACADS",3206,72,17446,1.66273307,1,0.269432805,0.258368552
GOTERM_MF_DIRECT,GO:0048029~monosaccharide binding,8,0.215111589,0.017021928,"GPI1, PFKL, TALDO1, PGLS, FUOM, TKT, FBP1, OGT",3206,16,17446,2.720835933,1,0.269432805,0.258368552
GOTERM_MF_DIRECT,GO:0042288~MHC class I protein binding,8,0.215111589,0.017021928,"BCAP31, PDIA3, H2-T23, ATP5B, VCP, TUBB5, ATP5A1, DERL1",3206,16,17446,2.720835933,1,0.269432805,0.258368552
GOTERM_MF_DIRECT,GO:0030145~manganese ion binding,16,0.430223178,0.017942729,"B4GALT1, GALNT2, GALNT1, SLC11A2, PEPD, SOD2, PPM1A, HMGCL, IMPA1, XPNPEP1, PAPOLA, ABL2, NUDT16, LAP3, CDIPT, GLUL",3206,47,17446,1.852484039,1,0.281993531,0.270413471
GOTERM_MF_DIRECT,GO:0004601~peroxidase activity,12,0.322667384,0.018074908,"PRDX3, PRDX2, GPX2, PRDX5, PRDX4, GPX1, GPX4, GPX3, PRDX1, CAT, PRDX6, TXNDC17",3206,31,17446,2.106453625,1,0.28207039,0.270487175
GOTERM_MF_DIRECT,GO:0004812~aminoacyl-tRNA ligase activity,14,0.376445281,0.018452682,"WARS, VARS, SARS, TARS, EPRS, NARS, LARS2, KARS, RARS, MARS, GARS, IARS, FARSA, FARSB",3206,39,17446,1.95342067,1,0.285952051,0.274209435
GOTERM_MF_DIRECT,GO:0000149~SNARE binding,20,0.537778973,0.018652574,"NAPA, SNAP25, NBAS, ANKRD27, STX17, EXOC3L4, STX16, STX8, STXBP1, GOSR2, STX7, CPLX2, CPLX1, ADCY6, VAMP8, SYT11, STX5A, STX3, VTI1B, VAMP3",3206,64,17446,1.700522458,1,0.287042387,0.275254997
GOTERM_MF_DIRECT,GO:0051787~misfolded protein binding,7,0.18822264,0.020161794,"BAG6, DNAJC3, SDF2L1, HSPA5, EDEM1, DNAJC10, HSPD1",3206,13,17446,2.930131004,1,0.305986404,0.293421078
GOTERM_MF_DIRECT,GO:0035497~cAMP response element binding,7,0.18822264,0.020161794,"ATF2, JUN, ATF6B, CREB3L3, CREB3L4, CREB3L1, ATF6",3206,13,17446,2.930131004,1,0.305986404,0.293421078
GOTERM_MF_DIRECT,GO:0005080~protein kinase C binding,18,0.484001076,0.020297835,"DSP, TOP2A, COPB2, SDC4, GLRX3, SRC, PRKCSH, ADD3, MARCKS, C1QBP, PARD3, SRSF2, AKT1, PICK1, RBCK1, PDLIM5, SQSTM1, YWHAG",3206,56,17446,1.749108814,1,0.305986404,0.293421078
GOTERM_MF_DIRECT,GO:0048306~calcium-dependent protein binding,21,0.564667921,0.020870178,"SNAP25, DDX5, TSG101, PDCD6IP, ANXA2, S100A1, ANXA4, PDCD6, CPLX2, SYN2, MYO1D, HNRNPM, CLN3, ANXA6, S100A6, CHP1, CALM3, CALM1, CALM2, S100A11, SEC31A",3206,69,17446,1.656161002,1,0.311544929,0.298751342
GOTERM_MF_DIRECT,GO:0034513~box H/ACA snoRNA binding,4,0.107555795,0.021369508,"DKC1, GAR1, NHP2, NOP10",3206,4,17446,5.441671865,1,0.311544929,0.298751342
GOTERM_MF_DIRECT,GO:0005047~signal recognition particle binding,4,0.107555795,0.021369508,"SRP72, SRPR, SRP68, SRP9",3206,4,17446,5.441671865,1,0.311544929,0.298751342
GOTERM_MF_DIRECT,GO:0000104~succinate dehydrogenase activity,4,0.107555795,0.021369508,"SDHC, SDHD, SDHA, SDHB",3206,4,17446,5.441671865,1,0.311544929,0.298751342
GOTERM_MF_DIRECT,GO:0050815~phosphoserine binding,4,0.107555795,0.021369508,"YWHAE, YWHAB, NEDD4, PIN1",3206,4,17446,5.441671865,1,0.311544929,0.298751342
GOTERM_MF_DIRECT,"GO:0051539~4 iron, 4 sulfur cluster binding",14,0.376445281,0.022857479,"ISCA1, IREB2, SDHB, NUBP1, NDUFS8, NDUFS7, POLD1, DPYD, REV3L, NDUFS2, ACO1, NDUFS1, ACO2, NDUFV1",3206,40,17446,1.904585153,1,0.331059962,0.317464991
GOTERM_MF_DIRECT,GO:0019900~kinase binding,26,0.699112665,0.02395436,"PFKFB2, ITGB1, CEBPA, HSP90AB1, CAB39, SRC, SLC2A1, PEBP1, PARK7, PRDX3, PRPSAP1, UBQLN1, RPS3, CHP1, PRKCD, NAP1L1, MOB4, DLG1, PFKL, CEACAM1, CDC37, TAX1BP1, CTNNB1, VIM, ATF5, FOXA2",3206,92,17446,1.537863788,1,0.344693904,0.330539055
GOTERM_MF_DIRECT,GO:0034237~protein kinase A regulatory subunit binding,8,0.215111589,0.024436086,"ARFGEF1, AKAP11, KCNQ1, AKAP9, AKAP7, PRKACA, EZR, PJA2",3206,17,17446,2.56078676,1,0.347117738,0.332863354
GOTERM_MF_DIRECT,GO:0003995~acyl-CoA dehydrogenase activity,8,0.215111589,0.024436086,"ACADVL, ACADL, ACOX1, ETFA, ACADM, ACAD11, ACADS, ACADSB",3206,17,17446,2.56078676,1,0.347117738,0.332863354
GOTERM_MF_DIRECT,GO:0042393~histone binding,33,0.887335305,0.024610594,"ANP32A, UHRF1, ZMYND8, CHD8, BAZ2A, MYSM1, PHF21B, CKS1B, CTSL, WDTC1, RNF20, NPM1, H3F3B, PHF12, PIH1D1, H3F3A, H2AFX, ATRX, SMARCA5, ELP2, BAZ1B, SMARCA2, CTCFL, DNAJC2, NASP, NCL, CKS2, ANP32E, NCAPD2, ANP32B, ZMYND11, PTMA, MCM2",3206,124,17446,1.448186867,1,0.347369912,0.333105172
GOTERM_MF_DIRECT,GO:0004722~protein serine/threonine phosphatase activity,17,0.457112127,0.025178591,"PPP1R15B, MTMR3, PPTC7, PTEN, PPP2R2A, PPM1J, PPM1G, PPP1CA, TIMM50, PPP1CB, CTDNEP1, PPP2CA, PPM1A, PPP1CC, PPP2CB, PPP3CA, PPP2R1A",3206,53,17446,1.745441919,1,0.353137713,0.33863612
GOTERM_MF_DIRECT,GO:0030234~enzyme regulator activity,9,0.242000538,0.027025852,"PRPSAP1, PSMD2, PSMD3, PSMD1, CALM3, GCLM, CALM1, COX6A1, CALM2",3206,21,17446,2.332145085,1,0.376662191,0.361194565
GOTERM_MF_DIRECT,GO:0008536~Ran GTPase binding,12,0.322667384,0.029029384,"RANBP1, RANBP3, XPO1, XPO6, NUP50, CSE1L, BIRC5, RANGRF, RANGAP1, TNPO2, KPNB1, IPO5",3206,33,17446,1.978789769,1,0.402056967,0.385546505
GOTERM_MF_DIRECT,"GO:0008553~hydrogen-exporting ATPase activity, phosphorylative mechanism",7,0.18822264,0.02990062,"ATP6V1G1, ATP6V0B, ATP5E, ATP6V0D1, ATP6V1E1, ATP6V1C1, ATP5L",3206,14,17446,2.720835933,1,0.407124759,0.390406188
GOTERM_MF_DIRECT,GO:0015175~neutral amino acid transmembrane transporter activity,7,0.18822264,0.02990062,"SLC36A1, SLC7A5, SLC6A19, SLC7A9, SLC3A2, SLC1A4, SLC1A5",3206,14,17446,2.720835933,1,0.407124759,0.390406188
GOTERM_MF_DIRECT,GO:0008144~drug binding,30,0.806668459,0.029946451,"TOP2A, PDXK, HSP90AB1, PNP2, GSTP1, NR1I2, HMGB2, ATP5O, PPP3CA, ADH1, PNP, FNTA, NPC1L1, NAMPT, SLC18A2, HMGCS1, CHKA, NME2, CYP4B1, ATP1B1, FABP1, FKBP1A, EEF1A1, P2RX4, CYP2C66, GSTA4, CYP2C65, FASN, ALB, PPARA",3206,112,17446,1.457590678,1,0.407124759,0.390406188
GOTERM_MF_DIRECT,GO:0032947~protein complex scaffold,15,0.40333423,0.032638209,"MAP2K2, AKAP7, SLC9A3R1, DLG1, AKAP11, CHCHD3, CNOT1, RB1CC1, AKAP9, LAMTOR2, LAMTOR1, LAMTOR4, LAMTOR3, TNRC6A, LAMTOR5",3206,46,17446,1.774458217,1,0.441013846,0.422903621
GOTERM_MF_DIRECT,GO:0019001~guanyl nucleotide binding,8,0.215111589,0.033791888,"GNA13, GNAO1, GNA11, GNAQ, GNAI3, GNAS, RAB5A, GNAI2",3206,18,17446,2.418520829,1,0.450214947,0.431726878
GOTERM_MF_DIRECT,GO:0017091~AU-rich element binding,8,0.215111589,0.033791888,"TIAL1, EXOSC7, TIA1, ZFP36, ELAVL1, ZFP36L2, ZFP36L1, HNRNPA0",3206,18,17446,2.418520829,1,0.450214947,0.431726878
GOTERM_MF_DIRECT,GO:0003755~peptidyl-prolyl cis-trans isomerase activity,14,0.376445281,0.033928654,"FKBP11, PPIL1, FKBP2, FKBP1A, PPIF, FKBP8, PIN1, PIN4, PPIG, FKBP4, PPIB, PPIA, PPID, NKTR",3206,42,17446,1.813890622,1,0.450214947,0.431726878
GOTERM_MF_DIRECT,GO:0008092~cytoskeletal protein binding,20,0.537778973,0.034480249,"ACTR2, GABARAPL1, MAP3K1, B4GALT1, DST, ANXA2, WASL, DYNLL2, CORO1B, SLC8A1, CDH1, PACSIN2, PICK1, ALDOC, CAPN1, ALDOB, EZR, ALDOA, DBN1, PLEC",3206,68,17446,1.600491725,1,0.454810897,0.436134096
GOTERM_MF_DIRECT,GO:0043130~ubiquitin binding,22,0.59155687,0.034993116,"TOP2A, TSG101, UBXN1, UBXN2A, FAF1, ADRM1, AUP1, CKS1B, D17WSU92E, DNAJC2, NBR1, NUP62, UBE2N, MVB12A, CKS2, TAX1BP1, RBCK1, BUB3, SQSTM1, OPTN, VPS28, TRP53INP2",3206,77,17446,1.55476339,1,0.458844643,0.440002196
GOTERM_MF_DIRECT,GO:0034450~ubiquitin-ubiquitin ligase activity,6,0.161333692,0.036148936,"AMFR, UBE4B, PRPF19, UBE2K, RBX1, ANAPC11",3206,11,17446,2.968184654,1,0.468777664,0.449527317
GOTERM_MF_DIRECT,GO:0016597~amino acid binding,11,0.295778435,0.036563436,"GCHFR, TPH1, DDC, MAT2A, KARS, SHMT2, SHMT1, CAD, GFPT1, GOT2, OTC",3206,30,17446,1.995279684,1,0.468777664,0.449527317
GOTERM_MF_DIRECT,GO:0017134~fibroblast growth factor binding,10,0.268889486,0.036591719,"HSPA9, CEP57, FGFBP1, RPS19, S100A13, RPS2, THBS1, FGFR3, GLG1, FGFRL1",3206,26,17446,2.092950717,1,0.468777664,0.449527317
GOTERM_MF_DIRECT,GO:0061630~ubiquitin protein ligase activity,48,1.290669535,0.036596812,"UHRF1, CUL3, UBR3, RNF6, PRPF19, RNF4, ANAPC11, CDC42, HECTD1, RNF114, MED10, TRIM2, HLTF, RBBP6, SKP1A, RNF44, ANKIB1, UBE2B, UBE2C, FBXW11, AMFR, MSL2, WWP2, UBE4B, UBE2G1, PJA2, RBX1, CDK8, RNF145, UBE2W, RNF126, CDC34, RNF128, UBE2R2, UBE2S, NEURL3, RFWD2, RNF149, NEDD4, UBE2N, UBE2V2, PELI1, RNF181, UBE2V1, UBE2K, CUL4B, ANAPC2, RNF220",3206,199,17446,1.312564068,1,0.468777664,0.449527317
GOTERM_MF_DIRECT,GO:0046983~protein dimerization activity,46,1.236891638,0.038426222,"THRA, PEF1, PDCD6, BHLHE41, DBI, GATA3, NR3C1, HIF1A, ASCL2, PYCARD, NEUROD1, PPP2CA, PPP3CA, PRDX5, AIFM1, MYC, POLR2C, MLX, HES1, POLR2J, ATOH1, BOK, MCL1, SREBF1, HES6, PDCD6IP, NUP210, FBXW11, STAT3, HPS4, ANO6, ANO7, BHLHA15, USF2, SYN2, SREBF2, DNM1, MLXIPL, CEACAM1, BHLHE40, ID1, POLR1C, POLR1D, ID3, GARS, TCF3",3206,190,17446,1.317457399,1,0.489382226,0.469285754
GOTERM_MF_DIRECT,GO:0003677~DNA binding,368,9.8951331,0.041643527,"APP, ATF2, EHF, SMARCB1, HNRNPU, MKI67, BACH1, RPL7, PNN, CREB3L3, TRIM28, CREB3L4, CREB3L1, MYC, GPBP1, MYB, LONP1, BBX, STRA13, SOX9, TRIM27, JUNB, IER2, SOX4, TMPO, HES6, SMARCC1, SMARCC2, SOX13, BHLHA15, RC3H2, SRRM1, THAP4, ZFP292, RFX6, SUB1, XRN2, TFAM, TBPL1, PREB, ATF5, ZFPM1, ATF6, ATF3, CGGBP1, ATF4, CASZ1, SET, DHX9, TSHZ1, GATA6, BAZ2A, GATA3, BAZ2B, ZBTB4, HIF1A, CHTF8, PCBP1, PRDM16, PCBP2, HLTF, DHX36, ZBTB7B, ZBTB7A, NKX2-2, CDT1, ZFP512, EGR1, JUN, XBP1, JUND, H3F3A, SMARCA5, NFATC3, PA2G4, SMARCA2, PBX1, NR2F6, HNRNPK, ZZZ3, FUBP1, HNRNPD, RNPS1, TOP2A, GMEB2, TCF25, PPP1R10, PHF20, BHLHE41, HNF4G, ASH2L, CTCF, TFCP2L1, AIFM1, HNF4A, ZMYM5, REV3L, MLX, JARID2, SREBF1, RMI2, PBRM1, PARP1, STRBP, ZFR, PAX6, ASH1L, FOS, SREBF2, MLF2, DDB1, TOX3, PLSCR1, NCOR1, CSDE1, PPARA, ZFP148, PCNA, TMF1, NR1I3, SRRT, NR1I2, ASCL2, CENPA, CENPB, PURB, BCLAF1, CHRAC1, RXRA, CUX1, HSF2, UBN1, RPS3, GPBP1L1, STAT6, RUNX1T1, SPDEF, MBD3, NPM1, PCGF6, CDX2, 0610010K14RIK, PTGES2, CDX1, MBD2, STAT3, RPA2, HIPK1, LRPPRC, HIST3H2A, PHF5A, MYBBP1A, NFIA, NFIB, NFIC, RPA3, CTNNB1, NUCB1, TCEA1, FOSB, HDGF, TARDBP, FOXA3, FOXA2, FOXA1, KDM1A, ZFAND3, ZFAND6, PDCD5, RORC, UBP1, RORB, TTF1, NR3C1, ETS1, ETS2, YY1, ZFP36, HMGN5, DACH1, KHSRP, HIST1H2AE, EP300, BANF1, ARID2, GM5176, HMGN2, HMGN3, GTF2I, HMGN1, HIST1H2AO, KDM2A, LIG1, APLP2, ARID5B, WRNIP1, FOXP4, MYT1, POU3F2, GTF2F2, FOXP1, ILF3, LMX1A, NCL, ADNP, NUPR1, GLYR1, HIST1H2BC, DNMT1, CBFB, DDX1, GTF2E2, ZFP36L2, ZFP36L1, NEUROD1, ZMAT2, DEAF1, G3BP1, SAFB2, EP400, CAMTA1, ESRRA, ZFHX3, VDR, FUS, NONO, SSH2, SMAD5, HOPX, NFKB1, NFKB2, CDK9, MLXIPL, H1F0, SON, NACA, SP1, TRP53, FEV, BCL3, ALB, BHLHE40, PIN4, TCF3, NFE2L1, NFE2L2, ZFP524, RERE, KDM5A, RNF10, DDX3X, MCM7, THRA, ONECUT2, LDB1, MCMDC2, CHD8, HP1BP3, CHD7, AKAP8L, HMGB2, HMGB3, ADAR, CHD4, YBX1, CHD3, HMGB1, YBX3, MYSM1, POLB, UBTF, HMG20B, WHSC1, LBR, HIST1H1C, TGIF1, KLF10, CERS4, KLF13, RFC1, H2AFY, H2AFZ, ATRX, DNMT3A, H2AFX, H2AFV, EDF1, ARID1A, SAFB, TSN, ETV6, DNAJC2, SFPQ, ELF1, ELF3, EEF1D, IRF1, POLR1C, IRF2, POLR1D, MCM3, IRF7, LUC7L3, MCM5, ANG, MCM6, IRF6, TOP1, LCORL, ZMYND11, ZFP410, AHDC1, CERS2, MCM2, ZFP787, NFAT5, CEBPA, ATF6B, POLDIP2, HDAC1, UHRF1, TAF9, CEBPG, CXXC1, RNF6, CXXC5, RNF4, TAF1D, PUF60, DNAJB6, POLR2B, POLD1, SAP30L, POLR2C, POLD2, POLR2E, POLR2F, HES1, POLR2H, RHOX8, POLR2J, ATOH1, POLR2K, POLR2L, SMARCE1, TCF7L2, CHURC1, TAF10, CNBP, SSRP1, SOD2, KLF4, HNRNPAB, KLF3, USF2, CTCFL, KLF6, KLF5, TEF, ERCC4, IMPDH1, IMPDH2, PDCD2, SSBP1, INSM1, SSBP2, SSBP3, TAF1",3206,1847,17446,1.084209662,1,0.523228014,0.501741665
GOTERM_MF_DIRECT,GO:0070742~C2H2 zinc finger domain binding,7,0.18822264,0.042269813,"U2AF2, EHMT2, ZXDB, ZXDC, MBD2, TAF9, EHMT1",3206,15,17446,2.53944687,1,0.523228014,0.501741665
GOTERM_MF_DIRECT,GO:0050661~NADP binding,13,0.349556332,0.042465932,"IDH1, GSR, HMGCR, PGD, FMO5, TM7SF2, GRHPR, POR, DPYD, CAT, G6PDX, DHCR7, GAPDH",3206,39,17446,1.813890622,1,0.523228014,0.501741665
GOTERM_MF_DIRECT,GO:0097157~pre-mRNA intronic binding,5,0.134444743,0.04250047,"HNRNPL, HNRNPA2B1, EP300, SOX9, PRPF8",3206,8,17446,3.401044916,1,0.523228014,0.501741665
GOTERM_MF_DIRECT,GO:1990405~protein antigen binding,5,0.134444743,0.04250047,"PPP2CA, HNRNPM, EP400, EP300, H2-AB1",3206,8,17446,3.401044916,1,0.523228014,0.501741665
GOTERM_MF_DIRECT,GO:0044389~ubiquitin-like protein ligase binding,5,0.134444743,0.04250047,"XBP1, VCP, PTPRN, TRIP4, CDK5RAP3",3206,8,17446,3.401044916,1,0.523228014,0.501741665
GOTERM_MF_DIRECT,GO:0051219~phosphoprotein binding,16,0.430223178,0.043464673,"YWHAE, YWHAB, SRC, PRKCSH, CSNK1A1, PIH1D1, ARRB1, PIK3R1, IGF2R, TOX3, THRAP3, BAG1, FKBP4, CD44, LRP11, PAFAH1B1",3206,52,17446,1.674360574,1,0.532142073,0.510289669
GOTERM_MF_DIRECT,GO:0005507~copper ion binding,18,0.484001076,0.044877664,"CUTA, PRNP, AHCY, COX17, SLC11A2, APOA4, PARK7, MT1, COMMD1, ATOX1, SOD1, P2RX4, HEPH, TRP53, S100A13, ANG, ADNP, PAM",3206,61,17446,1.605739239,1,0.532607678,0.510736153
GOTERM_MF_DIRECT,GO:0070006~metalloaminopeptidase activity,8,0.215111589,0.045250438,"NPEPPS, ENPEP, DNPEP, RNPEPL1, XPNPEP1, ANPEP, LTA4H, METAP2",3206,19,17446,2.291230259,1,0.532607678,0.510736153
GOTERM_MF_DIRECT,GO:0001540~beta-amyloid binding,11,0.295778435,0.045367497,"CST3, BACE1, OLFM1, CD74, BACE2, TM2D1, APOA1, APBA3, HSD17B10, ITM2B, ITM2C",3206,31,17446,1.930915823,1,0.532607678,0.510736153
GOTERM_MF_DIRECT,GO:0004332~fructose-bisphosphate aldolase activity,4,0.107555795,0.046146514,"ALDOART1, ALDOC, ALDOB, ALDOA",3206,5,17446,4.353337492,1,0.532607678,0.510736153
GOTERM_MF_DIRECT,GO:0051022~Rho GDP-dissociation inhibitor binding,4,0.107555795,0.046146514,"CDC42, HSP90AA1, RAC1, RHOA",3206,5,17446,4.353337492,1,0.532607678,0.510736153
GOTERM_MF_DIRECT,GO:1990932~5.8S rRNA binding,4,0.107555795,0.046146514,"RPS9, RPL6, RPS13, RPL19",3206,5,17446,4.353337492,1,0.532607678,0.510736153
GOTERM_MF_DIRECT,GO:0070061~fructose binding,4,0.107555795,0.046146514,"PFKL, ALDOB, SLC2A5, ALDOA",3206,5,17446,4.353337492,1,0.532607678,0.510736153
GOTERM_MF_DIRECT,GO:0047391~alkylglycerophosphoethanolamine phosphodiesterase activity,4,0.107555795,0.046146514,"GNA11, GNAQ, GNB1, GNAS",3206,5,17446,4.353337492,1,0.532607678,0.510736153
GOTERM_MF_DIRECT,GO:0070087~chromo shadow domain binding,4,0.107555795,0.046146514,"NIPBL, TRIM28, ATRX, LBR",3206,5,17446,4.353337492,1,0.532607678,0.510736153
GOTERM_MF_DIRECT,GO:0001882~nucleoside binding,4,0.107555795,0.046146514,"CDA, PNP, PNP2, ACTN4",3206,5,17446,4.353337492,1,0.532607678,0.510736153
GOTERM_MF_DIRECT,GO:0003724~RNA helicase activity,4,0.107555795,0.046146514,"DDX5, DDX21, SKIV2L, SKIV2L2",3206,5,17446,4.353337492,1,0.532607678,0.510736153
GOTERM_MF_DIRECT,GO:0000976~transcription regulatory region sequence-specific DNA binding,16,0.430223178,0.050682863,"EGR1, ZFP148, KDM3A, THRA, CBX3, HDAC1, GATA3, NFKB1, SFPQ, CREB3L3, TNRC18, SOX9, ATF6, SOX4, ATF3, NFE2L2",3206,53,17446,1.642768865,1,0.581933805,0.558036704
GOTERM_MF_DIRECT,GO:0044212~transcription regulatory region DNA binding,54,1.452003227,0.052115687,"FOXA1, RNF10, GABPB2, KDM1A, THRA, GMNN, HMGB2, ASH2L, ARRB1, CTCF, TTF1, YY1, HNF4A, CREB3L1, SOX9, SREBF1, H2AFY, ARID5B, PAX6, FOS, SREBF2, SFPQ, NCOR1, RFX6, ATF5, ATF3, ATF4, CEBPA, ATF6B, HDAC1, TAF9, GATA6, PHB, GATA3, RXRA, DHX36, TCF7L2, EGR1, XBP1, JUN, JUND, CDX1, STAT3, KLF4, SMARCA2, NFKB1, CTCFL, HNRNPL, CDK9, SP1, TRP53, CTNNB1, FOXA3, FOXA2",3206,233,17446,1.261160003,1,0.595300839,0.57085482
GOTERM_MF_DIRECT,GO:0051721~protein phosphatase 2A binding,12,0.322667384,0.053272242,"IGBP1, PPP2CA, PPME1, CPD, TRP53, EIF4EBP1, AKT1, PPP2R2A, VIM, HMGCR, ARPP19, STRN4",3206,36,17446,1.813890622,1,0.605391227,0.580530847
GOTERM_MF_DIRECT,GO:0070491~repressing transcription factor binding,11,0.295778435,0.055497234,"CBX5, CTBP1, HDAC1, ZFP703, HNF4A, MYC, GMNN, CTNNB1, SRI, PARK7, TCF3",3206,32,17446,1.870574704,1,0.624273456,0.598637678
GOTERM_MF_DIRECT,"GO:0016620~oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor",11,0.295778435,0.055497234,"ALDH3A2, ADH4, ALDH2, ALDH1B1, ALDH3B1, ALDH1A1, ALDH16A1, ALDH18A1, GAPDH, ALDH1A7, ALDH9A1",3206,32,17446,1.870574704,1,0.624273456,0.598637678
GOTERM_MF_DIRECT,GO:0004653~polypeptide N-acetylgalactosaminyltransferase activity,7,0.18822264,0.057418545,"GALNT12, GALNT7, GALNT6, GALNT4, GALNT2, GALNT1, GALNT10",3206,16,17446,2.380731441,1,0.636197475,0.610072037
GOTERM_MF_DIRECT,GO:0070577~lysine-acetylated histone binding,7,0.18822264,0.057418545,"BRD3, BRD2, PSME4, BAZ2A, PHIP, BAZ1B, TAF1",3206,16,17446,2.380731441,1,0.636197475,0.610072037
GOTERM_MF_DIRECT,"GO:0052890~oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor",7,0.18822264,0.057418545,"ACADVL, ACADL, ACOX1, ETFA, ACADM, ACAD11, ACADSB",3206,16,17446,2.380731441,1,0.636197475,0.610072037
GOTERM_MF_DIRECT,GO:0003756~protein disulfide isomerase activity,8,0.215111589,0.058924314,"PDIA3, ERP44, QSOX1, P4HB, PDIA6, PDIA5, TXNDC5, ERO1L",3206,20,17446,2.176668746,1,0.646417223,0.619872112
GOTERM_MF_DIRECT,GO:0042974~retinoic acid receptor binding,8,0.215111589,0.058924314,"MED25, SNW1, RXRA, NCOR1, CTBP2, CNOT1, NSD1, ACTN4",3206,20,17446,2.176668746,1,0.646417223,0.619872112
GOTERM_MF_DIRECT,"GO:0016746~transferase activity, transferring acyl groups",40,1.075557946,0.061300153,"AGPAT5, ALAS1, LPGAT1, ACAA2, MOGAT2, ZDHHC20, ACAA1A, AGPAT1, SAT1, ACNAT1, AGPAT2, OSGEP, AGPAT3, ZDHHC3, ACAT2, ACAT1, SPTLC1, CPT2, SPTLC2, SCP2, EP300, GGT1, TGM2, NAA50, CPT1A, DGAT2, NAA10, DGAT1, ELP3, HADHB, PLA2G16, NAT8, SOAT1, ZDHHC9, SOAT2, LPCAT3, NMT1, NAGS, CRAT, TAF1",3206,167,17446,1.303394459,1,0.669168176,0.641688797
GOTERM_MF_DIRECT,GO:0061133~endopeptidase activator activity,5,0.134444743,0.065606098,"PSMD14, ADRM1, PSME1, PSME2, ELP2",3206,9,17446,3.023151036,1,0.695612987,0.667047652
GOTERM_MF_DIRECT,GO:0043023~ribosomal large subunit binding,5,0.134444743,0.065606098,"RBM3, NPM1, EIF6, OLA1, EIF1A",3206,9,17446,3.023151036,1,0.695612987,0.667047652
GOTERM_MF_DIRECT,GO:0019887~protein kinase regulator activity,5,0.134444743,0.065606098,"HSP90AB1, APC, KIDINS220, CDC37, CSNK2B",3206,9,17446,3.023151036,1,0.695612987,0.667047652
GOTERM_MF_DIRECT,GO:0015194~L-serine transmembrane transporter activity,5,0.134444743,0.065606098,"SERINC1, SLC1A4, SLC1A5, SERINC3, SERINC2",3206,9,17446,3.023151036,1,0.695612987,0.667047652
GOTERM_MF_DIRECT,GO:0008190~eukaryotic initiation factor 4E binding,5,0.134444743,0.065606098,"DDX3X, LARP1, EIF4EBP1, EIF4G1, RBX1",3206,9,17446,3.023151036,1,0.695612987,0.667047652
GOTERM_MF_DIRECT,"GO:0016780~phosphotransferase activity, for other substituted phosphate groups",5,0.134444743,0.065606098,"EPT1, CHPT1, CEPT1, CDIPT, CRLS1",3206,9,17446,3.023151036,1,0.695612987,0.667047652
GOTERM_MF_DIRECT,GO:0035035~histone acetyltransferase binding,11,0.295778435,0.067004995,"EGR1, EID1, PCNA, CITED2, SP1, TRP53, TRIP4, PAX6, HIF1A, ZBTB7A, ETS1",3206,33,17446,1.813890622,1,0.707062234,0.678026736
GOTERM_MF_DIRECT,GO:0003727~single-stranded RNA binding,13,0.349556332,0.070896754,"CBX7, CBX6, THRA, STRBP, CNBP, MSI2, HMGB1, JMJD6, HNRNPF, LONP1, POLR2G, SNRPC, LSM14A",3206,42,17446,1.684327006,1,0.744583914,0.714007589
GOTERM_MF_DIRECT,GO:0043024~ribosomal small subunit binding,6,0.161333692,0.073217093,"PTCD3, NPM1, DDX3X, EIF4H, EIF4B, NME1",3206,13,17446,2.511540861,1,0.751153137,0.720307047
GOTERM_MF_DIRECT,GO:0030898~actin-dependent ATPase activity,6,0.161333692,0.073217093,"MYO1D, MYL6, MYO1B, MYO10, MYH14, MYH9",3206,13,17446,2.511540861,1,0.751153137,0.720307047
GOTERM_MF_DIRECT,GO:0044183~protein binding involved in protein folding,6,0.161333692,0.073217093,"CCT6A, CCT3, CD74, CCT2, DNAJB6, PFDN1",3206,13,17446,2.511540861,1,0.751153137,0.720307047
GOTERM_MF_DIRECT,GO:0042805~actinin binding,6,0.161333692,0.073217093,"HNRNPK, MICALL2, LMO7, PROM1, PDLIM5, NFKB1",3206,13,17446,2.511540861,1,0.751153137,0.720307047
GOTERM_MF_DIRECT,GO:0046873~metal ion transmembrane transporter activity,6,0.161333692,0.073217093,"SLC39A9, SLC39A11, SLC39A5, SLC39A7, SLC39A14, SLC39A4",3206,13,17446,2.511540861,1,0.751153137,0.720307047
GOTERM_MF_DIRECT,GO:0005543~phospholipid binding,23,0.618445819,0.074320551,"PRKCI, FAAH, BAD, PITPNB, PITPNA, PLA2G2A, GOT2, HIP1R, APOC3, AGAP1, APOA1, NBEAL2, FABP1, BAIAP2L2, DAB1, BDH1, CPS1, MAP1B, NUP62, APOB, SPTBN1, OTC, PICALM",3206,88,17446,1.422255147,1,0.757624541,0.726512703
GOTERM_MF_DIRECT,"GO:0016773~phosphotransferase activity, alcohol group as acceptor",8,0.215111589,0.074873544,"G6PC, MVK, HKDC1, FAM20B, ADK, GALK2, HK2, GALK1",3206,21,17446,2.073017853,1,0.757624541,0.726512703
GOTERM_MF_DIRECT,GO:0000993~RNA polymerase II core binding,8,0.215111589,0.074873544,"2700060E02RIK, ELOF1, CTR9, WAC, SMYD2, ELP2, ELP3, SMYD3",3206,21,17446,2.073017853,1,0.757624541,0.726512703
GOTERM_MF_DIRECT,GO:0048037~cofactor binding,7,0.18822264,0.075408977,"ACLY, PHYH, UROS, BIRC5, ASNS, SUCLG1, TKT",3206,17,17446,2.240688415,1,0.759574055,0.72838216
GOTERM_MF_DIRECT,GO:0043559~insulin binding,4,0.107555795,0.079860156,"PIK3R1, C2CD2L, IGF1R, HSPD1",3206,6,17446,3.627781244,1,0.776184678,0.744310668
GOTERM_MF_DIRECT,GO:0031749~D2 dopamine receptor binding,4,0.107555795,0.079860156,"CLIC6, PPP1R1B, DNM1, DNM2",3206,6,17446,3.627781244,1,0.776184678,0.744310668
GOTERM_MF_DIRECT,GO:0015093~ferrous iron transmembrane transporter activity,4,0.107555795,0.079860156,"SLC25A28, SLC11A2, SLC40A1, SLC39A14",3206,6,17446,3.627781244,1,0.776184678,0.744310668
GOTERM_MF_DIRECT,GO:0046975~histone methyltransferase activity (H3-K36 specific),4,0.107555795,0.079860156,"SETD3, NSD1, SMYD2, ASH1L",3206,6,17446,3.627781244,1,0.776184678,0.744310668
GOTERM_MF_DIRECT,GO:0001159~core promoter proximal region DNA binding,4,0.107555795,0.079860156,"HNRNPK, NFIC, EP300, NKX2-2",3206,6,17446,3.627781244,1,0.776184678,0.744310668
GOTERM_MF_DIRECT,GO:0004300~enoyl-CoA hydratase activity,4,0.107555795,0.079860156,"HADHB, HADHA, ECHS1, EHHADH",3206,6,17446,3.627781244,1,0.776184678,0.744310668
GOTERM_MF_DIRECT,GO:0008308~voltage-gated anion channel activity,4,0.107555795,0.079860156,"GPR89, VDAC3, VDAC2, VDAC1",3206,6,17446,3.627781244,1,0.776184678,0.744310668
GOTERM_MF_DIRECT,"GO:0016628~oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor",4,0.107555795,0.079860156,"DHCR24, DHCR7, LBR, TM7SF2",3206,6,17446,3.627781244,1,0.776184678,0.744310668
GOTERM_MF_DIRECT,GO:0004497~monooxygenase activity,27,0.726001613,0.082384544,"YWHAE, TPH1, YWHAB, CYP3A11, CYP3A13, CYP2C55, YWHAQ, CYP2B10, MICAL1, CYP4V3, YWHAG, CYP2J6, CYP4B1, MICAL2, CYP3A25, CYP2C29, FMO5, CYP4F13, CYP51, CYP4F14, CYP2D26, CYP4F16, CYP2C68, CYP2C66, CYP2C65, CYP2S1, PAM",3206,108,17446,1.360417966,1,0.795092356,0.762441902
GOTERM_MF_DIRECT,GO:0016791~phosphatase activity,29,0.779779511,0.085429432,"MTMR3, PTPRN, PTEN, PTPRK, DUSP18, ATP1A1, DUSP16, NT5C3, PTPRF, PTPRG, NT5C, PPP1CB, DUSP11, PPP1CC, ACP1, PTPRN2, DUSP1, SACM1L, SSH2, PPP1CA, PTPRD, DUSP22, CTDNEP1, PTP4A2, MINPP1, CTDSP2, PGP, FBP1, FBP2",3206,118,17446,1.337360035,1,0.795092356,0.762441902
GOTERM_MF_DIRECT,GO:0016779~nucleotidyltransferase activity,22,0.59155687,0.088425991,"CDS1, ZCCHC11, CMAS, PCYT2, GALT, PRIM1, UAP1, PAPSS2, PAPSS1, GMPPB, POLB, YRDC, CHRAC1, UGP2, POLR2B, POLD1, UAP1L1, GMPPA, POLD2, REV3L, PAPOLA, POLR2G",3206,85,17446,1.408432718,1,0.795092356,0.762441902
GOTERM_MF_DIRECT,GO:0016508~long-chain-enoyl-CoA hydratase activity,3,0.080666846,0.088831346,"HADHB, HADHA, HSD17B4",3206,3,17446,5.441671865,1,0.795092356,0.762441902
GOTERM_MF_DIRECT,GO:0030250~guanylate cyclase activator activity,3,0.080666846,0.088831346,"GUCA2B, RUNDC3A, GUCA2A",3206,3,17446,5.441671865,1,0.795092356,0.762441902
GOTERM_MF_DIRECT,GO:0070644~vitamin D response element binding,3,0.080666846,0.088831346,"RXRA, VDR, TCF3",3206,3,17446,5.441671865,1,0.795092356,0.762441902
GOTERM_MF_DIRECT,GO:0031800~type 3 metabotropic glutamate receptor binding,3,0.080666846,0.088831346,"CALM3, CALM1, CALM2",3206,3,17446,5.441671865,1,0.795092356,0.762441902
GOTERM_MF_DIRECT,GO:0004466~long-chain-acyl-CoA dehydrogenase activity,3,0.080666846,0.088831346,"ACADVL, ACADL, ACAD11",3206,3,17446,5.441671865,1,0.795092356,0.762441902
GOTERM_MF_DIRECT,GO:0016401~palmitoyl-CoA oxidase activity,3,0.080666846,0.088831346,"ACADL, ACOX1, ACAA1A",3206,3,17446,5.441671865,1,0.795092356,0.762441902
GOTERM_MF_DIRECT,GO:0070404~NADH binding,3,0.080666846,0.088831346,"QDPR, ALDH2, H2-KE6",3206,3,17446,5.441671865,1,0.795092356,0.762441902
GOTERM_MF_DIRECT,GO:0030519~snoRNP binding,3,0.080666846,0.088831346,"PRMT1, IMP3, IMP4",3206,3,17446,5.441671865,1,0.795092356,0.762441902
GOTERM_MF_DIRECT,GO:0070569~uridylyltransferase activity,3,0.080666846,0.088831346,"UGP2, UAP1L1, UAP1",3206,3,17446,5.441671865,1,0.795092356,0.762441902
GOTERM_MF_DIRECT,GO:0008177~succinate dehydrogenase (ubiquinone) activity,3,0.080666846,0.088831346,"SDHD, SDHA, SDHB",3206,3,17446,5.441671865,1,0.795092356,0.762441902
GOTERM_MF_DIRECT,GO:0019207~kinase regulator activity,3,0.080666846,0.088831346,"AKAP11, GSTP1, BCCIP",3206,3,17446,5.441671865,1,0.795092356,0.762441902
GOTERM_MF_DIRECT,GO:0004616~phosphogluconate dehydrogenase (decarboxylating) activity,3,0.080666846,0.088831346,"HIBADH, PGD, GLYR1",3206,3,17446,5.441671865,1,0.795092356,0.762441902
GOTERM_MF_DIRECT,GO:0001069~regulatory region RNA binding,3,0.080666846,0.088831346,"PTBP1, MBNL1, HNRNPA2B1",3206,3,17446,5.441671865,1,0.795092356,0.762441902
GOTERM_MF_DIRECT,GO:0001158~enhancer sequence-specific DNA binding,9,0.242000538,0.089029873,"YY1, ATF2, XBP1, LDB1, GATA6, HMGB2, SOX9, GATA3, MYT1",3206,26,17446,1.883655646,1,0.795092356,0.762441902
GOTERM_MF_DIRECT,GO:0050681~androgen receptor binding,9,0.242000538,0.089029873,"KDM3A, DDX5, KDM1A, NSD1, EP300, RNF6, PARK7, CALR, RNF4",3206,26,17446,1.883655646,1,0.795092356,0.762441902
GOTERM_MF_DIRECT,GO:0043425~bHLH transcription factor binding,9,0.242000538,0.089029873,"PSMD9, UBE2I, SP1, BHLHE40, BHLHE41, EP300, SOX9, TCF3, USF2",3206,26,17446,1.883655646,1,0.795092356,0.762441902
GOTERM_MF_DIRECT,GO:0050839~cell adhesion molecule binding,19,0.510890024,0.089114493,"DSP, ITGB1, CXADR, JUP, ANP32A, SRC, CTNND1, PTPRD, SDCBP, CDH1, CDHR2, CLDN7, NPTN, CPE, DSG2, CDHR5, PKP3, AMICA1, EZR",3206,71,17446,1.456222048,1,0.795092356,0.762441902
GOTERM_MF_DIRECT,GO:0005516~calmodulin binding,42,1.129335843,0.089340251,"CAMK2B, DDX5, UBR4, CACNA1A, PIK3R1, ADCY1, IQGAP1, IQGAP2, ADD3, EGFR, STRN4, SLC8A1, MYLK, CNN3, PPP3CA, MYO6, MKNK2, MYH14, KCNN4, SCN3A, SPTBN1, TRPM4, MARCKSL1, CAMK1D, MYO10, ATPIF1, CASK, EDF1, ATP2B1, CAMSAP3, MYO1D, MARCKS, PLCB3, MYO1B, CEACAM1, MYO1A, EWSR1, KCNQ1, CTH, MYO5B, MAPKAPK2, MYH9",3206,182,17446,1.25577043,1,0.795092356,0.762441902
GOTERM_MF_DIRECT,GO:0008233~peptidase activity,108,2.904006453,0.089864108,"SPPL2A, PARK7, CNDP2, NPEPPS, PLAU, NRD1, ANPEP, LONP1, PMPCB, PRSS8, CAPN1, GGT1, HABP2, PDIA3, USP7, ACE2, CLPP, LAP3, CFB, ENPEP, PSMD14, KLK1, PSEN1, ZMPSTE24, DPP3, DPP4, APH1A, AMZ2, LTA4H, RCE1, CTSA, ST14, H13, COPS5, CPD, CPE, TPP1, LGMN, PCSK1, USP38, CPQ, USP33, CTSZ, USP34, PCSK9, ECE1, PEPD, SPPL3, PCSK5, MYSM1, SCPEP1, CASP7, CASP6, CTSL, CASP1, CASP2, CTSF, PGPEP1, CTSD, HGFAC, CTSB, MMP7, TPSG1, DESI1, MME, BACE1, PSMA5, PSMA6, BACE2, IMMP1L, PSMA3, PSMA4, PSMA1, MEP1B, PSMA2, MPND, LTF, USP15, USP10, TMPRSS4, TMPRSS2, FURIN, USP19, PSMA7, PSMB10, PSMB6, PSMB7, PSMB4, DNPEP, PSMB5, PSMB2, PSMB3, PSMB1, FAM63B, FAM63A, SEC11A, SEC11C, USP24, USP9X, USP22, PSMB8, SPCS3, SPCS2, PSMC5, SPCS1, XPNPEP1, EIF3F, METAP2",3206,516,17446,1.138954576,1,0.796555456,0.763844921
GOTERM_MF_DIRECT,GO:0050998~nitric-oxide synthase binding,8,0.215111589,0.093104453,"CD74, CTNNB1, CALM3, CALM1, CALM2, ACTB, DNM1, DNM2",3206,22,17446,1.978789769,1,0.81924047,0.785598375
GOTERM_MF_DIRECT,GO:0048027~mRNA 5'-UTR binding,5,0.134444743,0.093902112,"RPS14, DDX3X, LARP1, ACO1, IGF2BP2",3206,10,17446,2.720835933,1,0.81924047,0.785598375
GOTERM_MF_DIRECT,GO:0050662~coenzyme binding,5,0.134444743,0.093902112,"TSTA3, GCLC, GCH1, HMGCR, ACAT1",3206,10,17446,2.720835933,1,0.81924047,0.785598375
GOTERM_MF_DIRECT,GO:0015266~protein channel activity,5,0.134444743,0.093902112,"TOMM40, TOMM7, TIMM17B, TOMM20, TOMM22",3206,10,17446,2.720835933,1,0.81924047,0.785598375
GOTERM_MF_DIRECT,GO:0097110~scaffold protein binding,15,0.40333423,0.094343781,"DSP, NLRP1A, MAP2K2, SRC, KRT8, CRIPT, PARK7, DLL1, CACNA1H, ADCY6, KRT18, KCNQ1, CASP1, VIM, MAPK3",3206,53,17446,1.540095811,1,0.819865952,0.786198171
GOTERM_MF_DIRECT,GO:0003678~DNA helicase activity,7,0.18822264,0.096217521,"MCM7, CHD8, RUVBL2, MCM3, MCM5, MCM6, MCM2",3206,18,17446,2.116205725,1,0.823235621,0.789429465
GOTERM_MF_DIRECT,GO:0008601~protein phosphatase type 2A regulator activity,7,0.18822264,0.096217521,"IGBP1, PPP2R1A, PPME1, PPP2R5B, PPP2R2A, PPP2R5C, ARPP19",3206,18,17446,2.116205725,1,0.823235621,0.789429465
GOTERM_MF_DIRECT,GO:0008266~poly(U) RNA binding,7,0.18822264,0.096217521,"KHDRBS1, RPS7, PABPC4, CIRBP, MSI2, HNRNPC, PABPC1",3206,18,17446,2.116205725,1,0.823235621,0.789429465
GOTERM_MF_DIRECT,GO:0001056~RNA polymerase III activity,7,0.18822264,0.096217521,"POLR1C, POLR1D, POLR2E, POLR2F, POLR2H, POLR2K, POLR2L",3206,18,17446,2.116205725,1,0.823235621,0.789429465