Table S3. Data of patients treated by immune checkpoint inhibitors,,,,,,, pair_id,RECIST,OS,OS_status,type,HER2,ICIs,HER2 mutation AC-DFCI_AC_PD1-1-TP-NT-SM-9LRI9-SM-9LRIA,CR,27.36666667,1,Anal,Mut,anti-PD-1/anti-PD-L1,p.I737M/p.G105E AL4602_T_N,SD,8.5,1,Lung,WT,anti-PD-1/anti-PD-L1,WT AU5884_T_N,PD,1.8,1,Lung,WT,anti-PD-1/anti-PD-L1,WT BL3403_T_N,SD,6.566666667,1,Lung,WT,anti-PD-1/anti-PD-L1,WT BLADDER-15330_CCPM_0700629-TM-NB-SM-AVI1C-SM-AVHZJ,PR,3.533333333,1,Bladder,WT,anti-PD-1/anti-PD-L1,WT BLADDER-15330_CCPM_0700691-TM-NB-SM-AVI13-SM-AVHZL,SD,5.8,0,Bladder,WT,anti-PD-1/anti-PD-L1,WT BLADDER-15330_CCPM_0700692-TM-NB-SM-AVI11-SM-AVHZM,SD,9.066666667,0,Bladder,WT,anti-PD-1/anti-PD-L1,WT BLADDER-15330_CCPM_0700694-TM-NB-SM-AVI16-SM-AVHZK,PR,9.566666667,1,Bladder,WT,anti-PD-1/anti-PD-L1,WT BLCA_immunotherapy_responder-DFCI_11-104_011-TP-NB-SM-5PA3E-SM-4D5IX,CR,44.93333333,1,Bladder,WT,anti-PD-1/anti-PD-L1,WT BLCA-001-TP-NB-SM-CUCGA-SM-CUCGU,PD,3.2,0,Bladder,WT,anti-PD-1/anti-PD-L1,WT BLCA-002-TP-NB-SM-CUCGB-SM-CUCGV,SD,16.93333333,1,Bladder,WT,anti-PD-1/anti-PD-L1,WT BLCA-003-TP-NB-SM-CUCGC-SM-CUCGW,PD,2.466666667,0,Bladder,WT,anti-PD-1/anti-PD-L1,WT BLCA-005-TP-NB-SM-CUCGE-SM-CUCGY,PR,16.76666667,1,Bladder,WT,anti-PD-1/anti-PD-L1,WT BLCA-006-TP-NB-SM-CUCGF-SM-CUCGZ,PR,12.26666667,0,Bladder,WT,anti-CTLA-4 + anti-PD-1/PD-L1,WT BLCA-007-TP-NB-SM-CUCGH-SM-CUCH1,CR,13.2,1,Bladder,WT,anti-PD-1/anti-PD-L1,WT BLCA-008-TP-NB-SM-CUCGI-SM-CUCH2,PD,3.5,0,Bladder,WT,anti-PD-1/anti-PD-L1,WT BLCA-009-TP-NB-SM-CUCGJ-SM-CUCH3,PD,4.733333333,0,Bladder,Mut,anti-PD-1/anti-PD-L1,p.S220F BLCA-010-TP-NB-SM-CUCGK-SM-CUCH4,PR,16.33333333,1,Bladder,WT,anti-PD-1/anti-PD-L1,WT BLCA-011-TP-NB-SM-CUCGL-SM-CUCH5,PD,5.633333333,0,Bladder,WT,anti-PD-1/anti-PD-L1,WT BLCA-012-TP-NB-SM-CUCGM-SM-CUCH6,PR,16.8,1,Bladder,WT,anti-PD-1/anti-PD-L1,WT BLCA-014-TP-NB-SM-CUCGO-SM-CUCH8,PD,12,1,Bladder,WT,anti-PD-1/anti-PD-L1,WT BLCA-015-TP-NB-SM-CUCGP-SM-CUCH9,PD,3.166666667,0,Bladder,WT,anti-PD-1/anti-PD-L1,WT BLCA-016-TP-NB-SM-CUCGQ-SM-CUCHA,PR,24.8,1,Bladder,WT,anti-PD-1/anti-PD-L1,WT BLCA-IM01-TP-NB-SM-79XD9-SM-7AABJ,PD,7.1,0,Bladder,WT,anti-PD-1/anti-PD-L1,WT BLCA-IM04-TP-NT-SM-79XDB-SM-79XDC,SD,6.5,0,Bladder,WT,anti-PD-1/anti-PD-L1,WT BLCA-IM06-TP-NB-SM-79XDL-SM-9QSPW,PD,24.33333333,1,Bladder,WT,anti-PD-1/anti-PD-L1,WT BLCA-IM07-TP-NB-SM-79XDD-SM-7AABP,PR,16.53333333,1,Bladder,WT,anti-PD-1/anti-PD-L1,WT BLCA-IM09-TP-NB-SM-79XDF-SM-7AABN,PR,22.1,0,Bladder,Mut,anti-PD-1/anti-PD-L1,p.D247H/p.E256Q BLCA-IM10-TP-NB-SM-79XDG-SM-9QSPX,CR,15.6,0,Bladder,WT,anti-PD-1/anti-PD-L1,WT BLCA-IM11-TP-NT-SM-79XDH-SM-79XDI,PR,13.7,0,Bladder,WT,anti-PD-1/anti-PD-L1,WT BLCA-IM12-TP-NB-SM-9RN2L-SM-9HC1F,PD,4.766666667,0,Bladder,WT,anti-PD-1/anti-PD-L1,WT CA9903_T_N,PR,14.7,1,Lung,WT,anti-PD-1/anti-PD-L1,WT CANSEQU01-0100425-TP-NB-SM-6ZL67-SM-6ZL66,PR,24.5,1,Lung,WT,anti-PD-1/anti-PD-L1,WT CR0095_T_N,CR,69.35,1,Melanoma,WT,anti-CTLA-4 ,WT CR04885_T_N,CR,25.55,1,Melanoma,WT,anti-CTLA-4 ,WT CR06670_T_N,CR,45.01666667,0,Melanoma,WT,anti-CTLA-4 ,WT CR1509_T_N,CR,54.75,1,Melanoma,WT,anti-CTLA-4 ,WT CR22640_T_N,CR,52.31666667,1,Melanoma,WT,anti-CTLA-4 ,WT CR3665_T_N,CR,32.85,1,Melanoma,WT,anti-CTLA-4 ,WT CR6126_T_N,CR,23.56666667,1,Melanoma,WT,anti-CTLA-4 ,WT CR6161_T_N,CR,31.73333333,0,Melanoma,WT,anti-CTLA-4 ,WT CR9306_T_N,CR,64.48333333,1,Melanoma,Mut,anti-CTLA-4 ,p.I684N CR9699_T_N,CR,53.53333333,1,Melanoma,WT,anti-CTLA-4 ,WT CU9061_T_N,SD,4.033333333,1,Lung,WT,anti-PD-1/anti-PD-L1,WT DFCI_MM_1-TP-NB-SM-BZRJ8-SM-BZRJC,CR,20,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT DFCI_MM_2-TP-NB-SM-BZRJA-SM-BZRJD,CR,12.16666667,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT DI6359_T_N,PR,9.933333333,1,Lung,WT,anti-PD-1/anti-PD-L1,WT DM123062_T_N,PD,1.9,1,Lung,WT,anti-PD-1/anti-PD-L1,WT FR9547_T_N,PR,4.233333333,1,Lung,WT,anti-PD-1/anti-PD-L1,WT GR4788_T_N,PD,1.9,1,Lung,WT,anti-PD-1/anti-PD-L1,WT HE3202_T_N,PR,14.9,1,Lung,WT,anti-PD-1/anti-PD-L1,WT HNSCC-186-TP-NB-SM-AXGDN-SM-ADP7L,SD,20.66666667,0,HNSCC,WT,anti-PD-1/anti-PD-L1,WT HNSCC-215-TP-NB-SM-CK9VX-SM-AV34O,PD,8.866666667,0,HNSCC,WT,anti-PD-1/anti-PD-L1,WT HNSCC-238-TP-NB-SM-AXGF5-SM-ADP7O,PR,15.33333333,1,HNSCC,WT,anti-PD-1/anti-PD-L1,WT HNSCC-239-TP-NB-SM-AXGCS-SM-ADP7K,SD,13.4,0,HNSCC,WT,anti-PD-1/anti-PD-L1,WT HNSCC-243-TP-NB-SM-CLFNS-SM-AV34T,PD,3.766666667,1,HNSCC,WT,anti-CTLA-4 + anti-PD-1/PD-L1,WT HNSCC-258-TP-NB-SM-AXGAI-SM-ADP7G,SD,12.6,1,HNSCC,WT,anti-PD-1/anti-PD-L1,WT HNSCC-266-TP-NB-SM-CK9YG-SM-AV34S,PD,2,0,HNSCC,WT,anti-PD-1/anti-PD-L1,WT HNSCC-287-TP-NB-SM-AXGEI-SM-ADP7M,PD,2.366666667,0,HNSCC,WT,anti-CTLA-4 + anti-PD-1/PD-L1,WT HNSCC-296-TP-NB-SM-CLFOB-SM-AV34U,SD,1.533333333,0,HNSCC,Mut,anti-PD-1/anti-PD-L1,p.S280F HNSCC-305-TP-NB-SM-CK9XQ-SM-AV34Q,SD,4.966666667,1,HNSCC,WT,anti-CTLA-4 + anti-PD-1/PD-L1,WT HNSCC-306-TP-NB-SM-CK9Y6-SM-AV34R,PD,5.633333333,1,HNSCC,WT,anti-CTLA-4 + anti-PD-1/PD-L1,WT HNSCC-323-TP-NB-SM-CK9WS-SM-AV34N,PR,4.666666667,1,HNSCC,WT,anti-PD-1/anti-PD-L1,WT JB112852_T_N,PD,3.333333333,1,Lung,WT,anti-PD-1/anti-PD-L1,WT KA3947_T_N,SD,8.2,1,Lung,WT,anti-PD-1/anti-PD-L1,WT LO3793_T_N,SD,3.533333333,1,Lung,WT,anti-PD-1/anti-PD-L1,WT LO5004_T_N,SD,6.366666667,1,Lung,WT,anti-PD-1/anti-PD-L1,WT LSD0167_T_N,SD,32.85,1,Melanoma,WT,anti-CTLA-4 ,WT LSD2057_T_N,SD,40.15,1,Melanoma,WT,anti-CTLA-4 ,WT LSD3484_T_N,SD,35.93333333,1,Melanoma,Mut,anti-CTLA-4 ,p.R940W LSD4744_T_N,SD,25.55,1,Melanoma,WT,anti-CTLA-4 ,WT LSD6819_T_N,SD,41.36666667,1,Melanoma,WT,anti-CTLA-4 ,WT LUAD-BS-08-013532-TP-NT-SM-9J2Y1-SM-9J2Y2,PR,8.1,0,Lung,WT,anti-PD-1/anti-PD-L1,WT LUAD-BS-10-J11656-TP-NT-SM-9J2Y7-SM-9J2Y8,SD,4.533333333,0,Lung,WT,anti-PD-1/anti-PD-L1,WT LUAD-BS-10-R22401-TP-NB-SM-9J2XK-SM-9HBZR,SD,3.966666667,0,Lung,WT,anti-PD-1/anti-PD-L1,WT LUAD-BS-11-F1305-TP-NT-SM-9J2XG-SM-9J2XH,SD,3.966666667,0,Lung,WT,anti-PD-1/anti-PD-L1,WT LUAD-BS-11-R21845-TP-NT-SM-9J2YH-SM-9J2YI,SD,59.36666667,1,Lung,WT,anti-PD-1/anti-PD-L1,WT LUAD-BS-12-R10269-TP-NB-SM-9J2XO-SM-9HBZT,PR,13.76666667,0,Lung,WT,anti-PD-1/anti-PD-L1,WT LUAD-BS-12-X27523-TP-NT-SM-9J2Y5-SM-9J2Y6,SD,10.86666667,0,Lung,WT,anti-PD-1/anti-PD-L1,WT LUAD-BS-13-F33496-TP-NB-SM-9J2XU-SM-9HBZX,SD,6.833333333,0,Lung,WT,anti-PD-1/anti-PD-L1,WT LUAD-BS-13-J60666-TP-NB-SM-9J2YL-SM-9HBZW,PR,33.3,1,Lung,Mut,anti-PD-1/anti-PD-L1,p.G434A LUAD-BS-13-N35728-TP-NB-SM-9J2XI-SM-9HBZQ,SD,12.8,0,Lung,WT,anti-PD-1/anti-PD-L1,WT LUAD-BS-13-X14864-TP-NB-SM-9J2XQ-SM-9HBZU,SD,5.866666667,0,Lung,WT,anti-PD-1/anti-PD-L1,WT LUAD-BS-14-G65174-TP-NT-SM-9J2YF-SM-9J2YG,PD,1.3,0,Lung,WT,anti-CTLA-4 + anti-PD-1/PD-L1,WT LUAD-BS-14-J45174-TP-NT-SM-9J2YJ-SM-9J2YK,PD,25.23333333,1,Lung,WT,anti-PD-1/anti-PD-L1,WT LUAD-BS-14-N19784-TP-NT-SM-9J2XW-SM-9J2XX,SD,27.26666667,0,Lung,WT,anti-PD-1/anti-PD-L1,WT LUNG-2630-TP-NB-SM-CLFOY-SM-AV34W,SD,15.73333333,0,Lung,WT,anti-PD-1/anti-PD-L1,WT Lung-DFCI-11-104-009-TM-NB-SM-5YS7O-SM-5YS7P,CR,22,1,Lung,WT,anti-PD-1/anti-PD-L1,WT M4945_T_N,PR,14.8,1,Lung,Mut,anti-PD-1/anti-PD-L1,p.A1009T MA7027_T_N,PD,1.8,1,Lung,WT,anti-PD-1/anti-PD-L1,WT MEL-582186-TP-NB-SM-CN21Q-SM-CJP7T,PR,13.83333333,1,Melanoma,WT,anti-CTLA-4 + anti-PD-1/PD-L1,WT MEL-587761-TP-NB-SM-CN1ZV-SM-CJP7Q,SD,19.46666667,1,Melanoma,WT,anti-CTLA-4 + anti-PD-1/PD-L1,WT MEL-650366-TP-NB-SM-CN221-SM-CJP7U,PD,26.46666667,1,Melanoma,WT,anti-CTLA-4 + anti-PD-1/PD-L1,WT MEL-682321-TP-NB-SM-CN21G-SM-CJP7S,PR,14.9,1,Melanoma,WT,anti-CTLA-4 + anti-PD-1/PD-L1,WT MEL-IPI_Pat02-TP-NB-SM-4DJZX-SM-4NFU4,SD,54.4,1,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat03-TP-NB-SM-4DJZY-SM-4NFU5,PD,3.333333333,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat04-TP-NB-SM-4DJZZ-SM-4NFU6,PR,32.9,1,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat06-TP-NB-SM-4DK12-SM-4NFU8,PD,5.366666667,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat07-TP-NB-SM-4DK13-SM-4NFU9,SD,35,1,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat08-TP-NB-SM-4DK14-SM-4NFUA,PD,4.666666667,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat100-TP-NT-SM-53U2D-SM-53U4M,PD,12,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat101-TP-NT-SM-4CU6O-SM-53U4N,PD,9.6,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat103-TP-NT-SM-4CU6Q-SM-53U4P,PR,34.93333333,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat104-TP-NT-SM-4CU6R-SM-53U4Q,SD,7.9,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat105-TP-NT-SM-4CU6S-SM-53U4R,PR,34.9,1,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat106-TP-NT-SM-4CU6T-SM-4MGPK,PD,8.333333333,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat11-TP-NB-SM-4DK17-SM-4NFUD,PD,26.33333333,1,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat110-TP-NT-SM-4CU6X-SM-4MGPO,PD,10.66666667,0,Melanoma,Mut,anti-CTLA-4 ,p.S280F MEL-IPI_Pat111-TP-NT-SM-4CU6Y-SM-4MGPP,PD,20.6,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat113-TP-NT-SM-53U2Q-SM-4MGPR,PR,10.03333333,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat115-TP-NT-SM-5X2QS-SM-5X2RA,PD,4.833333333,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat117-TP-NT-SM-5X2QU-SM-5X2RC,PR,30.46666667,1,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat118-TP-NT-SM-5X2QV-SM-5X2RD,PD,10.43333333,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat119-TP-NT-SM-7459N-SM-7459Q,PD,26.93333333,1,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat12-TP-NB-SM-7459O-SM-4NFUE,PD,9.666666667,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat121-TP-NT-SM-7459K-SM-5X2RG,PD,4.066666667,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat123-TP-NB-SM-5X2R1-SM-5VWHL,SD,28.43333333,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat124-TP-NB-SM-7459L-SM-5VWHM,PD,4.866666667,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat126-TP-NB-SM-5X2R4-SM-5VWHO,PR,21.36666667,1,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat127-TP-NB-SM-5X2R5-SM-5VWHP,PD,11.06666667,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat128-TP-NB-SM-5X2R6-SM-5VWHQ,PD,3.766666667,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat129-TP-NT-SM-5X2R7-SM-5X2RI,PD,17.96666667,1,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat13-TP-NB-SM-4DK19-SM-4NFUF,PD,24.4,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat132-TP-NB-SM-5VWJA-SM-5VWHR,PR,22.53333333,1,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat133-TP-NB-SM-7A14Z-SM-5VWHS,PD,18.06666667,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat134-TP-NB-SM-5VWJC-SM-5VWHT,PD,10.06666667,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat135-TP-NB-SM-7A152-SM-5VWHU,PD,2.7,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat138-TP-NB-SM-7A155-SM-5VWHX,SD,49.26666667,0,Melanoma,Mut,anti-CTLA-4 ,p.P1047L/p.S1024N/p.D952E/p.P36L MEL-IPI_Pat139-TP-NB-SM-5VWJH-SM-5VWHY,PD,3.3,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat14-TP-NB-SM-53U3C-SM-4NFUG,PD,5.433333333,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat140-TP-NB-SM-5VWJI-SM-5VWHZ,PD,16.4,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat143-TP-NB-SM-7A156-SM-5VWI3,PD,5.1,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat144-TP-NB-SM-7A157-SM-5VWI4,PR,29,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat147-TP-NB-SM-7A158-SM-5VWI7,PD,7.466666667,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat148-TP-NB-SM-5VWJQ-SM-5VWI8,PD,2.8,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat15-TP-NB-SM-4DK1B-SM-4NFUH,PD,1.666666667,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat151-TP-NB-SM-7A15A-SM-5VWIB,PD,6.8,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat157-TP-NB-SM-7A15B-SM-5VWIH,,2.866666667,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat159-TP-NB-SM-5VWK2-SM-5VWIJ,PD,28.06666667,1,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat16-TP-NT-SM-53U3E-SM-53U5B,PD,27.03333333,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat160-TP-NB-SM-5VWK3-SM-5VWIK,PD,5.066666667,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat162-TP-NB-SM-7A15D-SM-5VWIM,PD,7.033333333,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat163-TP-NB-SM-5VWK6-SM-5VWIN,PD,24.96666667,1,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat166-TP-NB-SM-7A15G-SM-5VWIQ,,2.566666667,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat167-TP-NB-SM-7A15H-SM-5VWIR,PD,13.6,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat168-TP-NB-SM-5VOAX-SM-5VWIS,,2.233333333,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat17-TP-NB-SM-4DK1D-SM-4NFUJ,PD,6.833333333,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat170-TP-NB-SM-5VOAZ-SM-5VWIU,PD,3.6,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat171-TP-NB-SM-7A15J-SM-5VWIV,PD,15.53333333,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat174-TP-NB-SM-5VOB4-SM-5VWIY,PR,22.93333333,1,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat175-TP-NB-SM-7A15L-SM-5VWIZ,,3,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat18-TP-NT-SM-4DK1E-SM-53U5D,PD,37.8,1,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat21-TP-NT-SM-4DK1H-SM-53U5G,SD,22.53333333,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat24-TP-NT-SM-4DK1K-SM-53U5J,PR,32.36666667,1,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat27-TP-NB-SM-4DK1N-SM-4NFUT,PD,45.96666667,1,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat32-TP-NT-SM-53U3T-SM-53U67,PD,4.9,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat39-TP-NB-SM-4DK1Z-SM-4NFV6,CR,49.56666667,1,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat41-TP-NT-SM-4DK22-SM-53U5O,PD,4.266666667,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat43-TP-NB-SM-4DK24-SM-4NFVA,PD,1.233333333,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat45-TP-NT-SM-4DK26-SM-53U5R,PD,2.966666667,0,Melanoma,Mut,anti-CTLA-4 ,p.G378D MEL-IPI_Pat46-TP-NT-SM-53U48-SM-53U5S,PD,5.333333333,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat47-TP-NT-SM-4DK28-SM-53U5U,CR,36.86666667,1,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat49-TP-NT-SM-4DK2A-SM-53U5W,SD,34.46666667,1,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat50-TP-NT-SM-53U69-SM-53U5X,PD,2.166666667,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat52-TP-NT-SM-4DK2D-SM-53U5Z,PD,6.3,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat54-TP-NB-SM-4DK2F-SM-4NFVL,PD,6.933333333,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat55-TP-NB-SM-4DK2G-SM-4NFVM,PD,6.433333333,0,Melanoma,Mut,anti-CTLA-4 ,p.G257R MEL-IPI_Pat56-TP-NB-SM-4DK2H-SM-4NFVN,PD,7.833333333,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat57-TP-NB-SM-4DK2I-SM-4NFVO,PD,8.333333333,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat58-TP-NB-SM-4DK2J-SM-4NFVP,PD,21.73333333,0,Melanoma,Mut,anti-CTLA-4 ,p.V988M MEL-IPI_Pat59-TP-NB-SM-4DK2K-SM-4NFVQ,PD,7.466666667,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat60-TP-NB-SM-4DK2L-SM-4NFVR,PD,9.066666667,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat61-TP-NB-SM-4DK2M-SM-4NFVS,PD,4.033333333,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat62-TP-NB-SM-4DK2N-SM-4NFVT,PD,20.06666667,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat64-TP-NB-SM-4DK2P-SM-4NFVV,PD,3.533333333,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat66-TP-NB-SM-4DK2R-SM-4NFVX,SD,21.76666667,1,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat67-TP-NB-SM-4DK2S-SM-4NFVY,PD,2.633333333,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat71-TP-NB-SM-4DK2W-SM-4NFW3,PD,4.566666667,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat73-TP-NB-SM-4DK2Y-SM-4NFW5,PR,14.73333333,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat74-TP-NB-SM-4DK2Z-SM-4NFW6,PD,6.433333333,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat76-TP-NB-SM-4DK32-SM-4NFW8,PD,4.633333333,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat77-TP-NT-SM-4DK33-SM-53U63,PR,34.3,1,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat79-TP-NB-SM-53U2S-SM-4NFWB,PR,26.7,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat80-TP-NT-SM-4DK36-SM-53U53,SD,24.13333333,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat81-TP-NB-SM-4DK37-SM-4NFWD,PD,20.93333333,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat82-TP-NT-SM-4DK38-SM-53U55,PD,3.466666667,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat83-TP-NT-SM-53U2W-SM-53U56,PD,34.23333333,1,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat85-TP-NB-SM-53U2Y-SM-4NFWH,PD,15.26666667,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat86-TP-NT-SM-4DK3C-SM-53U59,SD,9.766666667,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat87-TP-NT-SM-4DK3D-SM-53U5A,PD,36.43333333,1,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat90-TP-NB-SM-4DK3G-SM-4NFWM,PR,33.5,1,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat98-TP-NT-SM-4CU6L-SM-53U4K,PD,4.666666667,0,Melanoma,WT,anti-CTLA-4 ,WT MEL-IPI_Pat99-TP-NT-SM-4CU6M-SM-53U4L,PD,11.73333333,0,Melanoma,WT,anti-CTLA-4 ,WT NI9507_T_N,PD,1.9,1,Lung,WT,anti-PD-1/anti-PD-L1,WT NR1867_T_N,PD,18.25,1,Melanoma,WT,anti-CTLA-4 ,WT NR2137_T_N,PD,9.733333333,1,Melanoma,WT,anti-CTLA-4 ,WT NR3549_T_N,PD,6.083333333,1,Melanoma,WT,anti-CTLA-4 ,WT NR4018_T_N,PD,3.65,1,Melanoma,WT,anti-CTLA-4 ,WT NR4045_T_N,PD,20.68333333,1,Melanoma,WT,anti-CTLA-4 ,WT NR4083_T_N,PD,2.8,1,Melanoma,Mut,anti-CTLA-4 ,p.S42F NR4631_T_N,PD,6.083333333,1,Melanoma,WT,anti-CTLA-4 ,WT NR4810_T_N,PD,4.866666667,1,Melanoma,WT,anti-CTLA-4 ,WT NR4949_T_N,PD,8.516666667,1,Melanoma,WT,anti-CTLA-4 ,WT NR8815_T_N,PD,14.6,1,Melanoma,WT,anti-CTLA-4 ,WT NR9445_T_N,PD,2.433333333,1,Melanoma,WT,anti-CTLA-4 ,WT NR9449_T_N,PD,7.3,1,Melanoma,WT,anti-CTLA-4 ,WT NR9521_T_N,PD,32.85,1,Melanoma,WT,anti-CTLA-4 ,WT NR9705_T_N,PD,14.6,1,Melanoma,WT,anti-CTLA-4 ,WT NR9765_T_N,PD,25.55,1,Melanoma,WT,anti-CTLA-4 ,WT PR12117_T_N,PR,19.46666667,0,Melanoma,WT,anti-CTLA-4 ,WT PR4035_T_N,PR,51.1,1,Melanoma,WT,anti-CTLA-4 ,WT PR4046_T_N,PR,25.66666667,1,Melanoma,Mut,anti-CTLA-4 ,p.E782* PR4077_T_N,PR,74.21666667,1,Melanoma,WT,anti-CTLA-4 ,WT PR4091_T_N,PR,73.26666667,1,Melanoma,WT,anti-CTLA-4 ,WT PR4092_T_N,PR,74.21666667,1,Melanoma,Mut,anti-CTLA-4 ,p.Y1218H/p.A721V R7495_T_N,PD,1.4,1,Lung,WT,anti-PD-1/anti-PD-L1,WT RH090935_T_N,PR,10.53333333,1,Lung,WT,anti-PD-1/anti-PD-L1,WT RI1933_T_N,PR,16.8,1,Lung,WT,anti-PD-1/anti-PD-L1,WT RO3338_T_N,PD,2.1,1,Lung,WT,anti-PD-1/anti-PD-L1,WT SA9755_T_N,PR,8.5,1,Lung,WT,anti-PD-1/anti-PD-L1,WT SB010944_T_N,PR,27.66666667,1,Lung,WT,anti-PD-1/anti-PD-L1,WT SC0899_T_N,PR,12.76666667,1,Lung,WT,anti-PD-1/anti-PD-L1,WT SC6470_T_N,SD,8.4,1,Lung,WT,anti-PD-1/anti-PD-L1,WT SD0346_T_N,SD,35.28333333,0,Melanoma,WT,anti-CTLA-4 ,WT SD1494_T_N,SD,24.33333333,1,Melanoma,WT,anti-CTLA-4 ,WT SD2051_T_N,SD,9.733333333,0,Melanoma,WT,anti-CTLA-4 ,WT SD2056_T_N,SD,48.53333333,1,Melanoma,WT,anti-CTLA-4 ,WT SD5038_T_N,SD,14.6,0,Melanoma,WT,anti-CTLA-4 ,WT SD5118_T_N,SD,32.85,0,Melanoma,WT,anti-CTLA-4 ,WT SD5934_T_N,SD,19.46666667,0,Melanoma,WT,anti-CTLA-4 ,WT SD6336_T_N,SD,84.23333333,1,Melanoma,WT,anti-CTLA-4 ,WT SD6494_T_N,SD,8.516666667,0,Melanoma,WT,anti-CTLA-4 ,WT SD7357_T_N,SD,24.33333333,0,Melanoma,WT,anti-CTLA-4 ,WT SR070761_T_N,PD,3.433333333,1,Lung,WT,anti-PD-1/anti-PD-L1,WT SU2C_Lung-SU2C-DFCI-LUAD-1002-TP-NB-SM-AOL41-SM-A46NE,PD,16.16666667,1,Lung,WT,anti-PD-1/anti-PD-L1,WT SU2C_Lung-SU2C-DFCI-LUAD-1003-TP-NB-SM-AOL4D-SM-A46NF,PD,4.4,0,Lung,WT,anti-PD-1/anti-PD-L1,WT SU2C_Lung-SU2C-DFCI-LUAD-1004-TP-NB-SM-AOL4P-SM-A46NG,SD,12.1,0,Lung,WT,anti-PD-1/anti-PD-L1,WT SU2C_Lung-SU2C-DFCI-LUAD-1005-TP-NB-SM-AOL52-SM-A46NH,PD,11.3,0,Lung,WT,anti-PD-1/anti-PD-L1,WT SU2C_Lung-SU2C-DFCI-LUAD-1006-TP-NB-SM-AOL5E-SM-A46NI,PD,6.066666667,1,Lung,WT,anti-PD-1/anti-PD-L1,WT SU2C_Lung-SU2C-DFCI-LUAD-1010-TM-NB-SM-AOL6S-SM-A46NM,SD,10.06666667,0,Lung,WT,anti-PD-1/anti-PD-L1,WT SU2C_Lung-SU2C-DFCI-LUAD-1011-TM-NB-SM-AOL75-SM-A46NN,PD,5.9,0,Lung,WT,anti-PD-1/anti-PD-L1,WT SU2C_Lung-SU2C-DFCI-LUAD-1013-TP-NB-SM-AOL7V-SM-A46NP,PD,1.066666667,0,Lung,WT,anti-PD-1/anti-PD-L1,WT SU2C_Lung-SU2C-DFCI-LUAD-1016-TM-NB-SM-AOL8W-SM-A46NS,SD,14.96666667,1,Lung,WT,anti-PD-1/anti-PD-L1,WT SU2C_Lung-SU2C-DFCI-LUAD-1017-TM-NB-SM-AOL99-SM-A46NT,PR,14.43333333,1,Lung,WT,anti-PD-1/anti-PD-L1,WT SU2C_Lung-SU2C-DFCI-LUAD-1018-TP-NB-SM-AOL9H-SM-A46NU,PD,3.2,0,Lung,WT,anti-PD-1/anti-PD-L1,WT SU2C_Lung-SU2C-DFCI-LUAD-1020-TM-NB-SM-AOL3C-SM-A46NC,PR,29.9,1,Lung,WT,anti-PD-1/anti-PD-L1,WT WA7899_T_N,PD,1.9,1,Lung,WT,anti-PD-1/anti-PD-L1,WT Y2087_T_N,SD,8.4,1,Lung,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt1,PD,5.24590164,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt10,SD,8.393442623,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt100,PD,27.54098361,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt101,PR,27.34426229,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt102,SD,20.85245902,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt103,PD,15.86885246,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt104,PR,26.81967214,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt106,PD,2.983606557,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt108,SD,29.93442622,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt11,PD,27.44262296,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt13,PD,9.180327869,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt17,PD,1.868852459,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt18,PR,35.18032787,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt2,SD,9.016393444,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt23,,1.704918033,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt24,PD,4.885245903,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt25,PD,3.31147541,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt26,SD,31.21311475,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt27,PD,15.57377049,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt28,PD,24.26229508,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt29,PD,8.950819672,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt3,PR,37.50819671,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt30,CR,34.52459016,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt31,PD,31.50819672,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt32,PD,3.737704919,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt34,PR,27.34426229,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt36,SD,35.44262294,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt37,SD,21.18032787,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt38,SD,5.475409837,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt39,PD,5.44262295,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt4,SD,20.75409836,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt44,PR,35.83606556,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt46,PD,7.442622951,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt47,PD,23.54098361,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt48,CR,34.29508196,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt49,PR,27.11475409,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt5,PD,7.278688524,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt51,PD,1.868852459,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt52,PD,15.60655738,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt53,PR,14.19672131,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt54,PR,28.36065574,0,Melanoma,Mut,anti-PD-1/anti-PD-L1,p.Pro285Leu NIV3-PROG-Pt58,SD,16.36065574,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt59,SD,23.21311474,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt60,PD,24.1967213,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt62,PD,15.47540984,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt65,SD,22.68852459,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt66,PD,17.7704918,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt67,SD,33.83606557,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt68,PR,27.60655738,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt7,PR,37.67213114,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt70,SD,10.19672131,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt71,SD,8.06557377,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt72,PR,25.24590164,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt73,SD,9.213114753,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt74,,0.655737705,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt76,,0.327868853,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt77,SD,15.44262295,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt78,PD,2.557377049,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt79,SD,7.147540983,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt8,PD,8.491803279,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt82,SD,14.06557377,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt83,SD,15.14754098,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt84,PD,4.950819672,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt85,PD,29.63934425,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt86,PD,8.918032788,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt87,SD,31.93442622,0,Melanoma,Mut,anti-PD-1/anti-PD-L1,p.Ser1054Asn NIV3-NAIVE-Pt89,SD,27.67213115,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt9,PD,3.016393442,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt90,PD,5.704918033,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt92,SD,10.91803279,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt93,PD,27.83606558,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-NAIVE-Pt94,CR,32.16393442,0,Melanoma,WT,anti-PD-1/anti-PD-L1,WT NIV3-PROG-Pt98,SD,24.49180328,1,Melanoma,WT,anti-PD-1/anti-PD-L1,WT