Supplementary Table 7. Statistical analysis of 70 DEGs in 5 innate immune cell subsets.,,,,,,,,, gene,.y.,group1,group2,p,p.adj,p.format,p.signif,method,CellType CSF1R,score,Moderate,Severe,9.53E-22,2.90E-21,< 2e-16,****,T-test,CD14+ Monocyte WARS,score,Moderate,Severe,9.01E-19,2.70E-18,<2e-16,****,T-test,CD14+ Monocyte GZMB,score,Moderate,Severe,8.70E-45,2.60E-44,< 2e-16,****,T-test,CD14+ Monocyte LST1,score,Moderate,Severe,8.13E-102,2.40E-101,< 2e-16,****,T-test,CD14+ Monocyte IFITM3,score,Moderate,Severe,8.13E-05,0.00024,8.10E-05,****,T-test,CD14+ Monocyte AC020656.1,score,Moderate,Severe,7.66E-112,2.30E-111,< 2e-16,****,T-test,CD14+ Monocyte CCL5,score,Moderate,Severe,6.70E-119,2.00E-118,< 2e-16,****,T-test,CD14+ Monocyte FCGR3B,score,Moderate,Severe,6.53E-05,2.00E-04,6.50E-05,****,T-test,CD14+ Monocyte CCL3L1,score,Moderate,Severe,6.14E-126,1.80E-125,<2e-16,****,T-test,CD14+ Monocyte LYPD2,score,Moderate,Severe,5.90E-15,1.80E-14,5.90E-15,****,T-test,CD14+ Monocyte S100A9,score,Moderate,Severe,5.64E-66,1.70E-65,< 2e-16,****,T-test,CD14+ Monocyte G0S2,score,Moderate,Severe,5.51E-11,1.70E-10,5.50E-11,****,T-test,CD14+ Monocyte SOD2,score,Moderate,Severe,4.98E-13,1.50E-12,5.00E-13,****,T-test,CD14+ Monocyte CCL3,score,Moderate,Severe,4.53E-75,1.40E-74,<2e-16,****,T-test,CD14+ Monocyte CD14,score,Moderate,Severe,4.42E-101,1.30E-100,< 2e-16,****,T-test,CD14+ Monocyte CD36,score,Moderate,Severe,4.29E-31,1.30E-30,< 2e-16,****,T-test,CD14+ Monocyte CXCL8,score,Moderate,Severe,3.97E-34,1.20E-33,< 2e-16,****,T-test,CD14+ Monocyte S100A8,score,Moderate,Severe,3.95E-149,1.20E-148,<2e-16,****,T-test,CD14+ Monocyte SERPINA1,score,Moderate,Severe,3.93E-31,1.20E-30,<2e-16,****,T-test,CD14+ Monocyte TCF4,score,Moderate,Severe,3.93E-10,1.20E-09,3.90E-10,****,T-test,CD14+ Monocyte S100A12,score,Moderate,Severe,3.62E-113,1.10E-112,< 2e-16,****,T-test,CD14+ Monocyte IRF8,score,Moderate,Severe,3.18E-23,9.60E-23,<2e-16,****,T-test,CD14+ Monocyte C12orf75,score,Moderate,Severe,2.70E-17,8.10E-17,< 2e-16,****,T-test,CD14+ Monocyte VCAN,score,Moderate,Severe,2.34E-182,7.00E-182,<2e-16,****,T-test,CD14+ Monocyte HLA-DQA1,score,Moderate,Severe,2.23E-15,6.70E-15,2.20E-15,****,T-test,CD14+ Monocyte PPBP,score,Moderate,Severe,2.17E-55,6.50E-55,<2e-16,****,T-test,CD14+ Monocyte GCA,score,Moderate,Severe,2.13E-52,6.40E-52,<2e-16,****,T-test,CD14+ Monocyte HMOX1,score,Moderate,Severe,1.97E-16,5.90E-16,< 2e-16,****,T-test,CD14+ Monocyte HLA-DPA1,score,Moderate,Severe,1.85E-09,5.50E-09,1.80E-09,****,T-test,CD14+ Monocyte IFITM1,score,Moderate,Severe,1.76E-61,5.30E-61,<2e-16,****,T-test,CD14+ Monocyte HLA-DRB1,score,Moderate,Severe,1.72E-10,5.20E-10,1.70E-10,****,T-test,CD14+ Monocyte CSTA,score,Moderate,Severe,1.64E-113,4.90E-113,<2e-16,****,T-test,CD14+ Monocyte SLC25A37,score,Moderate,Severe,1.53E-27,4.60E-27,<2e-16,****,T-test,CD14+ Monocyte IFITM2,score,Moderate,Severe,1.45E-22,4.30E-22,<2e-16,****,T-test,CD14+ Monocyte SMIM25,score,Moderate,Severe,1.43E-15,4.30E-15,1.40E-15,****,T-test,CD14+ Monocyte GNLY,score,Moderate,Severe,1.42E-65,4.30E-65,<2e-16,****,T-test,CD14+ Monocyte MS4A6A,score,Moderate,Severe,1.40E-91,4.20E-91,< 2e-16,****,T-test,CD14+ Monocyte NKG7,score,Moderate,Severe,1.36E-128,4.10E-128,<2e-16,****,T-test,CD14+ Monocyte JUN,score,Moderate,Severe,1.36E-228,4.10E-228,<2e-16,****,T-test,CD14+ Monocyte PTGDS,score,Moderate,Severe,1.34E-27,4.00E-27,< 2e-16,****,T-test,CD14+ Monocyte MS4A7,score,Moderate,Severe,1.24E-24,3.70E-24,<2e-16,****,T-test,CD14+ Monocyte JCHAIN,score,Moderate,Severe,1.16E-18,3.50E-18,< 2e-16,****,T-test,CD14+ Monocyte FCGR3A,score,Moderate,Severe,1.15E-09,3.40E-09,1.10E-09,****,T-test,CD14+ Monocyte IL1B,score,Moderate,Severe,1.04E-97,3.10E-97,< 2e-16,****,T-test,CD14+ Monocyte ITM2C,score,Moderate,Severe,0.962831853,1,0.96,ns,T-test,CD14+ Monocyte IER3,score,Moderate,Severe,0.916385185,1,0.92,ns,T-test,CD14+ Monocyte S100P,score,Moderate,Severe,0.766883338,1,0.77,ns,T-test,CD14+ Monocyte CD74,score,Moderate,Severe,0.546020272,1,0.55,ns,T-test,CD14+ Monocyte PROK2,score,Moderate,Severe,0.387528215,1,0.39,ns,T-test,CD14+ Monocyte CXCL1,score,Moderate,Severe,0.282224717,0.85,0.28,ns,T-test,CD14+ Monocyte PI3,score,Moderate,Severe,0.26019407,0.78,0.26,ns,T-test,CD14+ Monocyte CDKN1C,score,Moderate,Severe,0.244541439,0.73,0.245,ns,T-test,CD14+ Monocyte PLD4,score,Moderate,Severe,0.170955538,0.51,0.17096,ns,T-test,CD14+ Monocyte RHOC,score,Moderate,Severe,0.142346562,0.43,0.142,ns,T-test,CD14+ Monocyte HLA-DRA,score,Moderate,Severe,0.114603985,0.34,0.11,ns,T-test,CD14+ Monocyte HLA-DQB1,score,Moderate,Severe,0.077323158,0.23,0.077,ns,T-test,CD14+ Monocyte NAMPT,score,Moderate,Severe,0.074703168,0.22,0.075,ns,T-test,CD14+ Monocyte SERPINF1,score,Moderate,Severe,0.074646809,0.22,0.075,ns,T-test,CD14+ Monocyte ALOX5AP,score,Moderate,Severe,0.059159883,0.18,0.0592,ns,T-test,CD14+ Monocyte CD1C,score,Moderate,Severe,0.047446828,0.14,0.04745,*,T-test,CD14+ Monocyte LYZ,score,Moderate,Severe,0.034993126,0.1,0.035,*,T-test,CD14+ Monocyte HLA-DPB1,score,Moderate,Severe,0.018281118,0.055,0.018,*,T-test,CD14+ Monocyte CLEC10A,score,Moderate,Severe,0.016453801,0.049,0.016,*,T-test,CD14+ Monocyte TCF7L2,score,Moderate,Severe,0.007251493,0.022,0.0073,**,T-test,CD14+ Monocyte FCER1A,score,Moderate,Severe,0.006915383,0.021,0.0069,**,T-test,CD14+ Monocyte CXCR2,score,Moderate,Severe,0.000671172,0.002,0.00067,***,T-test,CD14+ Monocyte IGKC,score,Moderate,Severe,0.00053248,0.0016,0.00053,***,T-test,CD14+ Monocyte CMTM2,score,Moderate,Severe,0.000333677,0.001,0.00033,***,T-test,CD14+ Monocyte IRF7,score,Moderate,Severe,0.000210233,0.00063,0.00021,***,T-test,CD14+ Monocyte PPBP,score,HD,Severe,9.61E-88,2.90E-87,<2e-16,****,T-test,CD14+ Monocyte S100A12,score,HD,Severe,9.06E-16,2.70E-15,9.10E-16,****,T-test,CD14+ Monocyte IL1B,score,HD,Severe,8.12E-40,2.40E-39,< 2e-16,****,T-test,CD14+ Monocyte SMIM25,score,HD,Severe,8.00E-16,2.40E-15,8.00E-16,****,T-test,CD14+ Monocyte IFITM3,score,HD,Severe,7.80E-63,2.30E-62,< 2e-16,****,T-test,CD14+ Monocyte CD74,score,HD,Severe,7.69E-06,2.30E-05,7.70E-06,****,T-test,CD14+ Monocyte PROK2,score,HD,Severe,6.45E-08,1.90E-07,6.40E-08,****,T-test,CD14+ Monocyte IGKC,score,HD,Severe,6.33E-12,1.90E-11,6.30E-12,****,T-test,CD14+ Monocyte IRF7,score,HD,Severe,5.77E-09,1.70E-08,5.80E-09,****,T-test,CD14+ Monocyte HLA-DQA1,score,HD,Severe,5.68E-31,1.70E-30,< 2e-16,****,T-test,CD14+ Monocyte MS4A6A,score,HD,Severe,5.18E-06,1.60E-05,5.20E-06,****,T-test,CD14+ Monocyte JCHAIN,score,HD,Severe,4.65E-50,1.40E-49,< 2e-16,****,T-test,CD14+ Monocyte CCL3L1,score,HD,Severe,4.64E-21,1.40E-20,<2e-16,****,T-test,CD14+ Monocyte CD14,score,HD,Severe,4.14E-29,1.20E-28,< 2e-16,****,T-test,CD14+ Monocyte CD36,score,HD,Severe,3.95E-10,1.20E-09,3.90E-10,****,T-test,CD14+ Monocyte HLA-DRB1,score,HD,Severe,3.84E-25,1.20E-24,< 2e-16,****,T-test,CD14+ Monocyte IER3,score,HD,Severe,3.83E-09,1.10E-08,3.80E-09,****,T-test,CD14+ Monocyte IFITM2,score,HD,Severe,3.56E-25,1.10E-24,<2e-16,****,T-test,CD14+ Monocyte SERPINA1,score,HD,Severe,3.50E-20,1.10E-19,<2e-16,****,T-test,CD14+ Monocyte S100A9,score,HD,Severe,2.73E-12,8.20E-12,2.70E-12,****,T-test,CD14+ Monocyte LST1,score,HD,Severe,2.70E-11,8.10E-11,2.70E-11,****,T-test,CD14+ Monocyte HLA-DQB1,score,HD,Severe,2.31E-08,6.90E-08,2.30E-08,****,T-test,CD14+ Monocyte CCL3,score,HD,Severe,2.31E-22,6.90E-22,<2e-16,****,T-test,CD14+ Monocyte JUN,score,HD,Severe,2.08E-77,6.30E-77,<2e-16,****,T-test,CD14+ Monocyte CSF1R,score,HD,Severe,1.93E-05,5.80E-05,1.90E-05,****,T-test,CD14+ Monocyte CSTA,score,HD,Severe,1.88E-21,5.60E-21,<2e-16,****,T-test,CD14+ Monocyte CMTM2,score,HD,Severe,1.84E-25,5.50E-25,< 2e-16,****,T-test,CD14+ Monocyte HMOX1,score,HD,Severe,1.77E-09,5.30E-09,1.80E-09,****,T-test,CD14+ Monocyte S100P,score,HD,Severe,1.35E-11,4.00E-11,1.30E-11,****,T-test,CD14+ Monocyte AC020656.1,score,HD,Severe,1.29E-08,3.90E-08,1.30E-08,****,T-test,CD14+ Monocyte GZMB,score,HD,Severe,1.14E-06,3.40E-06,1.10E-06,****,T-test,CD14+ Monocyte VCAN,score,HD,Severe,0.960303302,1,0.96,ns,T-test,CD14+ Monocyte IRF8,score,HD,Severe,0.953586754,1,0.95,ns,T-test,CD14+ Monocyte CXCL1,score,HD,Severe,0.939576288,1,0.94,ns,T-test,CD14+ Monocyte SLC25A37,score,HD,Severe,0.828311624,1,0.83,ns,T-test,CD14+ Monocyte NKG7,score,HD,Severe,0.792590501,1,0.79,ns,T-test,CD14+ Monocyte CLEC10A,score,HD,Severe,0.683798214,1,0.684,ns,T-test,CD14+ Monocyte ITM2C,score,HD,Severe,0.674710648,1,0.67,ns,T-test,CD14+ Monocyte TCF7L2,score,HD,Severe,0.619748774,1,0.6197,ns,T-test,CD14+ Monocyte GCA,score,HD,Severe,0.567867202,1,0.57,ns,T-test,CD14+ Monocyte CXCR2,score,HD,Severe,0.563153304,1,0.56315,ns,T-test,CD14+ Monocyte HLA-DPB1,score,HD,Severe,0.529544544,1,0.53,ns,T-test,CD14+ Monocyte PI3,score,HD,Severe,0.523402757,1,0.52,ns,T-test,CD14+ Monocyte G0S2,score,HD,Severe,0.280740396,0.84,0.28,ns,T-test,CD14+ Monocyte SERPINF1,score,HD,Severe,0.279942848,0.84,0.28,ns,T-test,CD14+ Monocyte WARS,score,HD,Severe,0.236184767,0.71,0.24,ns,T-test,CD14+ Monocyte HLA-DRA,score,HD,Severe,0.227341986,0.68,0.23,ns,T-test,CD14+ Monocyte GNLY,score,HD,Severe,0.148579677,0.45,0.15,ns,T-test,CD14+ Monocyte IFITM1,score,HD,Severe,0.100806351,0.3,0.1,ns,T-test,CD14+ Monocyte SOD2,score,HD,Severe,0.093641149,0.28,0.094,ns,T-test,CD14+ Monocyte ALOX5AP,score,HD,Severe,0.085895339,0.26,0.0859,ns,T-test,CD14+ Monocyte NAMPT,score,HD,Severe,0.079825561,0.24,0.08,ns,T-test,CD14+ Monocyte S100A8,score,HD,Severe,0.067722728,0.2,0.068,ns,T-test,CD14+ Monocyte MS4A7,score,HD,Severe,0.0661952,0.2,0.066,ns,T-test,CD14+ Monocyte FCGR3A,score,HD,Severe,0.044859386,0.13,0.045,*,T-test,CD14+ Monocyte FCER1A,score,HD,Severe,0.021745408,0.065,0.0217,*,T-test,CD14+ Monocyte RHOC,score,HD,Severe,0.018306726,0.055,0.018,*,T-test,CD14+ Monocyte CDKN1C,score,HD,Severe,0.014020348,0.042,0.014,*,T-test,CD14+ Monocyte TCF4,score,HD,Severe,0.008666947,0.026,0.0087,**,T-test,CD14+ Monocyte C12orf75,score,HD,Severe,0.007211701,0.022,0.0072,**,T-test,CD14+ Monocyte LYPD2,score,HD,Severe,0.006780874,0.02,0.00678,**,T-test,CD14+ Monocyte FCGR3B,score,HD,Severe,0.005186586,0.016,0.0052,**,T-test,CD14+ Monocyte LYZ,score,HD,Severe,0.004359637,0.013,0.0044,**,T-test,CD14+ Monocyte HLA-DPA1,score,HD,Severe,0.0006209,0.0019,0.00062,***,T-test,CD14+ Monocyte CCL5,score,HD,Severe,0.000534957,0.0016,0.00053,***,T-test,CD14+ Monocyte PTGDS,score,HD,Severe,0.000406917,0.0012,0.00041,***,T-test,CD14+ Monocyte PLD4,score,HD,Severe,0.000320215,0.00096,0.00032,***,T-test,CD14+ Monocyte CXCL8,score,HD,Severe,0.000286473,0.00086,0.00029,***,T-test,CD14+ Monocyte CD1C,score,HD,Severe,0.000115596,0.00035,0.00012,***,T-test,CD14+ Monocyte CSTA,score,HD,Moderate,9.90E-25,3.00E-24,<2e-16,****,T-test,CD14+ Monocyte CD74,score,HD,Moderate,9.43E-06,2.80E-05,9.40E-06,****,T-test,CD14+ Monocyte VCAN,score,HD,Moderate,7.40E-127,2.20E-126,<2e-16,****,T-test,CD14+ Monocyte GNLY,score,HD,Moderate,6.99E-50,2.10E-49,<2e-16,****,T-test,CD14+ Monocyte PPBP,score,HD,Moderate,6.84E-191,2.10E-190,<2e-16,****,T-test,CD14+ Monocyte SLC25A37,score,HD,Moderate,6.61E-20,2.00E-19,<2e-16,****,T-test,CD14+ Monocyte CXCL8,score,HD,Moderate,6.44E-37,1.90E-36,< 2e-16,****,T-test,CD14+ Monocyte IL1B,score,HD,Moderate,5.41E-09,1.60E-08,5.40E-09,****,T-test,CD14+ Monocyte CD14,score,HD,Moderate,5.27E-14,1.60E-13,5.30E-14,****,T-test,CD14+ Monocyte HLA-DRB1,score,HD,Moderate,5.13E-05,0.00015,5.10E-05,****,T-test,CD14+ Monocyte CD36,score,HD,Moderate,4.93E-53,1.50E-52,< 2e-16,****,T-test,CD14+ Monocyte CCL5,score,HD,Moderate,4.69E-54,1.40E-53,< 2e-16,****,T-test,CD14+ Monocyte SOD2,score,HD,Moderate,4.58E-14,1.40E-13,4.60E-14,****,T-test,CD14+ Monocyte S100A8,score,HD,Moderate,4.34E-73,1.30E-72,<2e-16,****,T-test,CD14+ Monocyte NKG7,score,HD,Moderate,4.25E-83,1.30E-82,<2e-16,****,T-test,CD14+ Monocyte JCHAIN,score,HD,Moderate,3.87E-06,1.20E-05,3.90E-06,****,T-test,CD14+ Monocyte FCGR3A,score,HD,Moderate,3.71E-11,1.10E-10,3.70E-11,****,T-test,CD14+ Monocyte PROK2,score,HD,Moderate,3.70E-05,0.00011,3.70E-05,****,T-test,CD14+ Monocyte S100P,score,HD,Moderate,3.68E-09,1.10E-08,3.70E-09,****,T-test,CD14+ Monocyte GCA,score,HD,Moderate,3.50E-42,1.10E-41,<2e-16,****,T-test,CD14+ Monocyte IRF8,score,HD,Moderate,3.35E-17,1.00E-16,<2e-16,****,T-test,CD14+ Monocyte G0S2,score,HD,Moderate,3.34E-10,1.00E-09,3.30E-10,****,T-test,CD14+ Monocyte AC020656.1,score,HD,Moderate,3.27E-46,9.80E-46,< 2e-16,****,T-test,CD14+ Monocyte IER3,score,HD,Moderate,3.10E-07,9.30E-07,3.10E-07,****,T-test,CD14+ Monocyte CCL3,score,HD,Moderate,2.05E-115,6.10E-115,<2e-16,****,T-test,CD14+ Monocyte MS4A7,score,HD,Moderate,2.03E-12,6.10E-12,2.00E-12,****,T-test,CD14+ Monocyte CMTM2,score,HD,Moderate,2.00E-11,6.00E-11,2.00E-11,****,T-test,CD14+ Monocyte S100A12,score,HD,Moderate,1.75E-30,5.20E-30,< 2e-16,****,T-test,CD14+ Monocyte IFITM1,score,HD,Moderate,1.66E-48,5.00E-48,<2e-16,****,T-test,CD14+ Monocyte LST1,score,HD,Moderate,1.50E-31,4.50E-31,< 2e-16,****,T-test,CD14+ Monocyte WARS,score,HD,Moderate,1.39E-17,4.20E-17,<2e-16,****,T-test,CD14+ Monocyte PTGDS,score,HD,Moderate,1.35E-07,4.10E-07,1.40E-07,****,T-test,CD14+ Monocyte HLA-DQB1,score,HD,Moderate,1.32E-10,4.00E-10,1.30E-10,****,T-test,CD14+ Monocyte C12orf75,score,HD,Moderate,1.30E-05,3.90E-05,1.30E-05,****,T-test,CD14+ Monocyte GZMB,score,HD,Moderate,1.29E-49,3.90E-49,< 2e-16,****,T-test,CD14+ Monocyte CSF1R,score,HD,Moderate,1.24E-05,3.70E-05,1.20E-05,****,T-test,CD14+ Monocyte S100A9,score,HD,Moderate,1.18E-13,3.50E-13,1.20E-13,****,T-test,CD14+ Monocyte CCL3L1,score,HD,Moderate,1.12E-156,3.30E-156,<2e-16,****,T-test,CD14+ Monocyte FCGR3B,score,HD,Moderate,1.03E-08,3.10E-08,1.00E-08,****,T-test,CD14+ Monocyte MS4A6A,score,HD,Moderate,1.03E-37,3.10E-37,< 2e-16,****,T-test,CD14+ Monocyte IFITM3,score,HD,Moderate,1.02E-31,3.10E-31,< 2e-16,****,T-test,CD14+ Monocyte NAMPT,score,HD,Moderate,0.939958685,1,0.94,ns,T-test,CD14+ Monocyte HLA-DRA,score,HD,Moderate,0.839756716,1,0.84,ns,T-test,CD14+ Monocyte FCER1A,score,HD,Moderate,0.748297518,1,0.7483,ns,T-test,CD14+ Monocyte ITM2C,score,HD,Moderate,0.746809675,1,0.75,ns,T-test,CD14+ Monocyte SMIM25,score,HD,Moderate,0.654469787,1,0.65,ns,T-test,CD14+ Monocyte SERPINF1,score,HD,Moderate,0.552030067,1,0.552,ns,T-test,CD14+ Monocyte CXCL1,score,HD,Moderate,0.407040021,1,0.41,ns,T-test,CD14+ Monocyte LYZ,score,HD,Moderate,0.377083086,1,0.3771,ns,T-test,CD14+ Monocyte SERPINA1,score,HD,Moderate,0.26092229,0.78,0.26,ns,T-test,CD14+ Monocyte CDKN1C,score,HD,Moderate,0.234242214,0.7,0.234,ns,T-test,CD14+ Monocyte IFITM2,score,HD,Moderate,0.231832102,0.7,0.23,ns,T-test,CD14+ Monocyte PI3,score,HD,Moderate,0.137682546,0.41,0.14,ns,T-test,CD14+ Monocyte HMOX1,score,HD,Moderate,0.128514483,0.39,0.13,ns,T-test,CD14+ Monocyte CD1C,score,HD,Moderate,0.076130766,0.23,0.07613,ns,T-test,CD14+ Monocyte HLA-DPA1,score,HD,Moderate,0.055120833,0.17,0.05512,ns,T-test,CD14+ Monocyte IRF7,score,HD,Moderate,0.036753931,0.11,0.03675,*,T-test,CD14+ Monocyte PLD4,score,HD,Moderate,0.031603628,0.095,0.0316,*,T-test,CD14+ Monocyte JUN,score,HD,Moderate,0,0,<2e-16,****,T-test,CD14+ Monocyte CLEC10A,score,HD,Moderate,0.015703763,0.047,0.016,*,T-test,CD14+ Monocyte HLA-DPB1,score,HD,Moderate,0.012170715,0.037,0.012,*,T-test,CD14+ Monocyte TCF7L2,score,HD,Moderate,0.00762125,0.023,0.0076,**,T-test,CD14+ Monocyte IGKC,score,HD,Moderate,0.006323242,0.019,0.00632,**,T-test,CD14+ Monocyte TCF4,score,HD,Moderate,0.002366204,0.0071,0.0024,**,T-test,CD14+ Monocyte ALOX5AP,score,HD,Moderate,0.002092584,0.0063,0.0021,**,T-test,CD14+ Monocyte RHOC,score,HD,Moderate,0.001009364,0.003,0.001,**,T-test,CD14+ Monocyte LYPD2,score,HD,Moderate,0.000535882,0.0016,0.00054,***,T-test,CD14+ Monocyte CXCR2,score,HD,Moderate,0.000535706,0.0016,0.00054,***,T-test,CD14+ Monocyte HLA-DQA1,score,HD,Moderate,0.000464328,0.0014,0.00046,***,T-test,CD14+ Monocyte CDKN1C,score,Moderate,Severe,8.02E-05,0.00024,8.00E-05,****,T-test,FCGR3A+ Monocyte JUN,score,Moderate,Severe,6.26E-37,1.90E-36,<2e-16,****,T-test,FCGR3A+ Monocyte IFITM1,score,Moderate,Severe,5.40E-08,1.60E-07,5.40E-08,****,T-test,FCGR3A+ Monocyte CCL3L1,score,Moderate,Severe,4.88E-06,1.50E-05,4.90E-06,****,T-test,FCGR3A+ Monocyte GCA,score,Moderate,Severe,4.14E-05,0.00012,4.10E-05,****,T-test,FCGR3A+ Monocyte GNLY,score,Moderate,Severe,3.38E-05,1.00E-04,3.40E-05,****,T-test,FCGR3A+ Monocyte CCL5,score,Moderate,Severe,3.32E-15,1.00E-14,3.30E-15,****,T-test,FCGR3A+ Monocyte PLD4,score,Moderate,Severe,2.66E-06,8.00E-06,2.70E-06,****,T-test,FCGR3A+ Monocyte LYZ,score,Moderate,Severe,1.31E-09,3.90E-09,1.30E-09,****,T-test,FCGR3A+ Monocyte TCF7L2,score,Moderate,Severe,1.06E-05,3.20E-05,1.10E-05,****,T-test,FCGR3A+ Monocyte CXCL1,score,Moderate,Severe,0.980412695,1,0.98,ns,T-test,FCGR3A+ Monocyte S100A8,score,Moderate,Severe,0.967218662,1,0.9672,ns,T-test,FCGR3A+ Monocyte CXCL8,score,Moderate,Severe,0.959953637,1,0.96,ns,T-test,FCGR3A+ Monocyte S100A12,score,Moderate,Severe,0.935545617,1,0.94,ns,T-test,FCGR3A+ Monocyte NKG7,score,Moderate,Severe,0.881365849,1,0.88,ns,T-test,FCGR3A+ Monocyte HLA-DRA,score,Moderate,Severe,0.829953585,1,0.83,ns,T-test,FCGR3A+ Monocyte HLA-DQA1,score,Moderate,Severe,0.794749627,1,0.79,ns,T-test,FCGR3A+ Monocyte SERPINF1,score,Moderate,Severe,0.789219809,1,0.79,ns,T-test,FCGR3A+ Monocyte S100A9,score,Moderate,Severe,0.773810444,1,0.774,ns,T-test,FCGR3A+ Monocyte IRF7,score,Moderate,Severe,0.576464529,1,0.58,ns,T-test,FCGR3A+ Monocyte CMTM2,score,Moderate,Severe,0.544476602,1,0.54,ns,T-test,FCGR3A+ Monocyte PROK2,score,Moderate,Severe,0.535113248,1,0.54,ns,T-test,FCGR3A+ Monocyte MS4A6A,score,Moderate,Severe,0.448816929,1,0.45,ns,T-test,FCGR3A+ Monocyte CD74,score,Moderate,Severe,0.440458984,1,0.44046,ns,T-test,FCGR3A+ Monocyte PI3,score,Moderate,Severe,0.36258825,1,0.36,ns,T-test,FCGR3A+ Monocyte IFITM3,score,Moderate,Severe,0.318971532,0.96,0.32,ns,T-test,FCGR3A+ Monocyte SOD2,score,Moderate,Severe,0.273977701,0.82,0.27,ns,T-test,FCGR3A+ Monocyte FCER1A,score,Moderate,Severe,0.273238842,0.82,0.27,ns,T-test,FCGR3A+ Monocyte CLEC10A,score,Moderate,Severe,0.242815238,0.73,0.24,ns,T-test,FCGR3A+ Monocyte S100P,score,Moderate,Severe,0.231384358,0.69,0.23138,ns,T-test,FCGR3A+ Monocyte HLA-DPB1,score,Moderate,Severe,0.219358689,0.66,0.21936,ns,T-test,FCGR3A+ Monocyte G0S2,score,Moderate,Severe,0.219110975,0.66,0.21911,ns,T-test,FCGR3A+ Monocyte HLA-DQB1,score,Moderate,Severe,0.216734926,0.65,0.2167,ns,T-test,FCGR3A+ Monocyte TCF4,score,Moderate,Severe,0.180967956,0.54,0.18,ns,T-test,FCGR3A+ Monocyte PTGDS,score,Moderate,Severe,0.180853747,0.54,0.18,ns,T-test,FCGR3A+ Monocyte IER3,score,Moderate,Severe,0.176189932,0.53,0.176,ns,T-test,FCGR3A+ Monocyte SLC25A37,score,Moderate,Severe,0.148827789,0.45,0.149,ns,T-test,FCGR3A+ Monocyte ALOX5AP,score,Moderate,Severe,0.14543925,0.44,0.145,ns,T-test,FCGR3A+ Monocyte IRF8,score,Moderate,Severe,0.09615339,0.29,0.096,ns,T-test,FCGR3A+ Monocyte FCGR3B,score,Moderate,Severe,0.088917722,0.27,0.0889,ns,T-test,FCGR3A+ Monocyte MS4A7,score,Moderate,Severe,0.08619828,0.26,0.086,ns,T-test,FCGR3A+ Monocyte WARS,score,Moderate,Severe,0.082630295,0.25,0.083,ns,T-test,FCGR3A+ Monocyte CXCR2,score,Moderate,Severe,0.061613875,0.18,0.062,ns,T-test,FCGR3A+ Monocyte VCAN,score,Moderate,Severe,0.047170486,0.14,0.0472,*,T-test,FCGR3A+ Monocyte JCHAIN,score,Moderate,Severe,0.041289005,0.12,0.041,*,T-test,FCGR3A+ Monocyte CD1C,score,Moderate,Severe,0.040097448,0.12,0.04,*,T-test,FCGR3A+ Monocyte IFITM2,score,Moderate,Severe,0.032025454,0.096,0.032,*,T-test,FCGR3A+ Monocyte LYPD2,score,Moderate,Severe,0.019999868,0.06,0.02,*,T-test,FCGR3A+ Monocyte GZMB,score,Moderate,Severe,0.016484587,0.049,0.016,*,T-test,FCGR3A+ Monocyte HLA-DRB1,score,Moderate,Severe,0.015827054,0.047,0.016,*,T-test,FCGR3A+ Monocyte NAMPT,score,Moderate,Severe,0.012000586,0.036,0.012,*,T-test,FCGR3A+ Monocyte LST1,score,Moderate,Severe,0.010317973,0.031,0.01,*,T-test,FCGR3A+ Monocyte AC020656.1,score,Moderate,Severe,0.009833206,0.029,0.00983,**,T-test,FCGR3A+ Monocyte RHOC,score,Moderate,Severe,0.008284746,0.025,0.0083,**,T-test,FCGR3A+ Monocyte PPBP,score,Moderate,Severe,0.008141625,0.024,0.0081,**,T-test,FCGR3A+ Monocyte IL1B,score,Moderate,Severe,0.005476872,0.016,0.0055,**,T-test,FCGR3A+ Monocyte ITM2C,score,Moderate,Severe,0.004036767,0.012,0.004,**,T-test,FCGR3A+ Monocyte SMIM25,score,Moderate,Severe,0.002851745,0.0086,0.0029,**,T-test,FCGR3A+ Monocyte CCL3,score,Moderate,Severe,0.002414338,0.0072,0.0024,**,T-test,FCGR3A+ Monocyte IGKC,score,Moderate,Severe,0.001783639,0.0054,0.0018,**,T-test,FCGR3A+ Monocyte CSTA,score,Moderate,Severe,0.001284984,0.0039,0.0013,**,T-test,FCGR3A+ Monocyte HMOX1,score,Moderate,Severe,0.000763313,0.0023,0.00076,***,T-test,FCGR3A+ Monocyte C12orf75,score,Moderate,Severe,0.000550708,0.0017,0.00055,***,T-test,FCGR3A+ Monocyte FCGR3A,score,Moderate,Severe,0.000350962,0.0011,0.00035,***,T-test,FCGR3A+ Monocyte CSF1R,score,Moderate,Severe,0.000271552,0.00081,0.00027,***,T-test,FCGR3A+ Monocyte CD36,score,Moderate,Severe,0.000181322,0.00054,0.00018,***,T-test,FCGR3A+ Monocyte CD14,score,Moderate,Severe,0.0001768,0.00053,0.00018,***,T-test,FCGR3A+ Monocyte HLA-DPA1,score,Moderate,Severe,0.000166243,5.00E-04,0.00017,***,T-test,FCGR3A+ Monocyte SERPINA1,score,Moderate,Severe,0.000124912,0.00037,0.00012,***,T-test,FCGR3A+ Monocyte IFITM1,score,HD,Severe,9.64E-05,0.00029,9.60E-05,****,T-test,FCGR3A+ Monocyte SMIM25,score,HD,Severe,7.89E-35,2.40E-34,<2e-16,****,T-test,FCGR3A+ Monocyte FCGR3B,score,HD,Severe,7.70E-06,2.30E-05,7.70E-06,****,T-test,FCGR3A+ Monocyte PLD4,score,HD,Severe,6.44E-09,1.90E-08,6.40E-09,****,T-test,FCGR3A+ Monocyte HMOX1,score,HD,Severe,5.36E-22,1.60E-21,< 2e-16,****,T-test,FCGR3A+ Monocyte LST1,score,HD,Severe,4.88E-35,1.50E-34,<2e-16,****,T-test,FCGR3A+ Monocyte IFITM3,score,HD,Severe,4.76E-34,1.40E-33,<2e-16,****,T-test,FCGR3A+ Monocyte SOD2,score,HD,Severe,4.63E-05,0.00014,4.60E-05,****,T-test,FCGR3A+ Monocyte FCGR3A,score,HD,Severe,4.27E-19,1.30E-18,< 2e-16,****,T-test,FCGR3A+ Monocyte SERPINA1,score,HD,Severe,4.12E-26,1.20E-25,< 2e-16,****,T-test,FCGR3A+ Monocyte IL1B,score,HD,Severe,4.05E-08,1.20E-07,4.00E-08,****,T-test,FCGR3A+ Monocyte TCF7L2,score,HD,Severe,3.40E-08,1.00E-07,3.40E-08,****,T-test,FCGR3A+ Monocyte WARS,score,HD,Severe,3.09E-11,9.30E-11,3.10E-11,****,T-test,FCGR3A+ Monocyte CSF1R,score,HD,Severe,2.46E-10,7.40E-10,2.50E-10,****,T-test,FCGR3A+ Monocyte IFITM2,score,HD,Severe,2.44E-45,7.30E-45,<2e-16,****,T-test,FCGR3A+ Monocyte CSTA,score,HD,Severe,2.07E-07,6.20E-07,2.10E-07,****,T-test,FCGR3A+ Monocyte MS4A7,score,HD,Severe,2.02E-24,6.00E-24,< 2e-16,****,T-test,FCGR3A+ Monocyte HLA-DQA1,score,HD,Severe,1.71E-11,5.10E-11,1.70E-11,****,T-test,FCGR3A+ Monocyte CCL5,score,HD,Severe,1.62E-05,4.90E-05,1.60E-05,****,T-test,FCGR3A+ Monocyte GNLY,score,HD,Severe,1.58E-05,4.80E-05,1.60E-05,****,T-test,FCGR3A+ Monocyte IRF7,score,HD,Severe,1.57E-07,4.70E-07,1.60E-07,****,T-test,FCGR3A+ Monocyte RHOC,score,HD,Severe,1.50E-25,4.50E-25,< 2e-16,****,T-test,FCGR3A+ Monocyte NAMPT,score,HD,Severe,1.38E-17,4.10E-17,<2e-16,****,T-test,FCGR3A+ Monocyte CDKN1C,score,HD,Severe,1.16E-15,3.50E-15,1.20E-15,****,T-test,FCGR3A+ Monocyte LYZ,score,HD,Severe,1.13E-09,3.40E-09,1.10E-09,****,T-test,FCGR3A+ Monocyte CMTM2,score,HD,Severe,0.881673688,1,0.88,ns,T-test,FCGR3A+ Monocyte PI3,score,HD,Severe,0.878174653,1,0.88,ns,T-test,FCGR3A+ Monocyte HLA-DRB1,score,HD,Severe,0.709160976,1,0.709,ns,T-test,FCGR3A+ Monocyte CLEC10A,score,HD,Severe,0.642797174,1,0.64,ns,T-test,FCGR3A+ Monocyte SERPINF1,score,HD,Severe,0.640534515,1,0.64,ns,T-test,FCGR3A+ Monocyte PROK2,score,HD,Severe,0.550262595,1,0.55,ns,T-test,FCGR3A+ Monocyte CD36,score,HD,Severe,0.472622874,1,0.47262,ns,T-test,FCGR3A+ Monocyte CXCR2,score,HD,Severe,0.426067554,1,0.426,ns,T-test,FCGR3A+ Monocyte IER3,score,HD,Severe,0.417752811,1,0.418,ns,T-test,FCGR3A+ Monocyte CCL3,score,HD,Severe,0.406710635,1,0.4067,ns,T-test,FCGR3A+ Monocyte GZMB,score,HD,Severe,0.403848912,1,0.404,ns,T-test,FCGR3A+ Monocyte FCER1A,score,HD,Severe,0.397215286,1,0.4,ns,T-test,FCGR3A+ Monocyte NKG7,score,HD,Severe,0.358966895,1,0.36,ns,T-test,FCGR3A+ Monocyte CXCL8,score,HD,Severe,0.356854714,1,0.36,ns,T-test,FCGR3A+ Monocyte PTGDS,score,HD,Severe,0.29336555,0.88,0.29,ns,T-test,FCGR3A+ Monocyte SLC25A37,score,HD,Severe,0.236077795,0.71,0.236,ns,T-test,FCGR3A+ Monocyte MS4A6A,score,HD,Severe,0.213816457,0.64,0.21,ns,T-test,FCGR3A+ Monocyte HLA-DRA,score,HD,Severe,0.171787998,0.52,0.17,ns,T-test,FCGR3A+ Monocyte LYPD2,score,HD,Severe,0.169701838,0.51,0.1697,ns,T-test,FCGR3A+ Monocyte TCF4,score,HD,Severe,0.164234107,0.49,0.16,ns,T-test,FCGR3A+ Monocyte S100A12,score,HD,Severe,0.150255249,0.45,0.15,ns,T-test,FCGR3A+ Monocyte C12orf75,score,HD,Severe,0.147509647,0.44,0.14751,ns,T-test,FCGR3A+ Monocyte ITM2C,score,HD,Severe,0.142895468,0.43,0.143,ns,T-test,FCGR3A+ Monocyte CXCL1,score,HD,Severe,0.116470427,0.35,0.12,ns,T-test,FCGR3A+ Monocyte CD14,score,HD,Severe,0.095955578,0.29,0.09596,ns,T-test,FCGR3A+ Monocyte CD1C,score,HD,Severe,0.068797298,0.21,0.069,ns,T-test,FCGR3A+ Monocyte IRF8,score,HD,Severe,0.062908985,0.19,0.063,ns,T-test,FCGR3A+ Monocyte ALOX5AP,score,HD,Severe,0.050855883,0.15,0.051,ns,T-test,FCGR3A+ Monocyte JUN,score,HD,Severe,0.034828296,0.1,0.035,*,T-test,FCGR3A+ Monocyte CCL3L1,score,HD,Severe,0.032799336,0.098,0.033,*,T-test,FCGR3A+ Monocyte IGKC,score,HD,Severe,0.027509652,0.083,0.0275,*,T-test,FCGR3A+ Monocyte JCHAIN,score,HD,Severe,0.022826703,0.068,0.023,*,T-test,FCGR3A+ Monocyte S100A9,score,HD,Severe,0.019441197,0.058,0.019,*,T-test,FCGR3A+ Monocyte GCA,score,HD,Severe,0.013889622,0.042,0.014,*,T-test,FCGR3A+ Monocyte HLA-DPB1,score,HD,Severe,0.013832263,0.041,0.01383,*,T-test,FCGR3A+ Monocyte HLA-DPA1,score,HD,Severe,0.006875741,0.021,0.00688,**,T-test,FCGR3A+ Monocyte VCAN,score,HD,Severe,0.003396881,0.01,0.0034,**,T-test,FCGR3A+ Monocyte CD74,score,HD,Severe,0.002144015,0.0064,0.00214,**,T-test,FCGR3A+ Monocyte S100A8,score,HD,Severe,0.001885042,0.0057,0.0019,**,T-test,FCGR3A+ Monocyte PPBP,score,HD,Severe,0.001781998,0.0053,0.0018,**,T-test,FCGR3A+ Monocyte HLA-DQB1,score,HD,Severe,0.001150464,0.0035,0.0012,**,T-test,FCGR3A+ Monocyte AC020656.1,score,HD,Severe,0.000731352,0.0022,0.00073,***,T-test,FCGR3A+ Monocyte G0S2,score,HD,Severe,0.000720123,0.0022,0.00072,***,T-test,FCGR3A+ Monocyte S100P,score,HD,Severe,0.000212919,0.00064,0.00021,***,T-test,FCGR3A+ Monocyte VCAN,score,HD,Moderate,9.35E-06,2.80E-05,9.30E-06,****,T-test,FCGR3A+ Monocyte IFITM1,score,HD,Moderate,8.86E-17,2.70E-16,< 2e-16,****,T-test,FCGR3A+ Monocyte IRF7,score,HD,Moderate,8.76E-08,2.60E-07,8.80E-08,****,T-test,FCGR3A+ Monocyte RHOC,score,HD,Moderate,8.62E-13,2.60E-12,8.60E-13,****,T-test,FCGR3A+ Monocyte CD36,score,HD,Moderate,8.02E-05,0.00024,8.00E-05,****,T-test,FCGR3A+ Monocyte IFITM2,score,HD,Moderate,7.63E-26,2.30E-25,<2e-16,****,T-test,FCGR3A+ Monocyte LYZ,score,HD,Moderate,6.62E-29,2.00E-28,< 2e-16,****,T-test,FCGR3A+ Monocyte PPBP,score,HD,Moderate,4.13E-07,1.20E-06,4.10E-07,****,T-test,FCGR3A+ Monocyte MS4A7,score,HD,Moderate,4.09E-15,1.20E-14,4.10E-15,****,T-test,FCGR3A+ Monocyte G0S2,score,HD,Moderate,3.39E-05,1.00E-04,3.40E-05,****,T-test,FCGR3A+ Monocyte WARS,score,HD,Moderate,3.14E-06,9.40E-06,3.10E-06,****,T-test,FCGR3A+ Monocyte CCL3L1,score,HD,Moderate,3.08E-08,9.20E-08,3.10E-08,****,T-test,FCGR3A+ Monocyte SERPINA1,score,HD,Moderate,2.99E-11,9.00E-11,3.00E-11,****,T-test,FCGR3A+ Monocyte HLA-DQA1,score,HD,Moderate,2.58E-09,7.80E-09,2.60E-09,****,T-test,FCGR3A+ Monocyte IFITM3,score,HD,Moderate,2.21E-32,6.60E-32,<2e-16,****,T-test,FCGR3A+ Monocyte FCGR3A,score,HD,Moderate,1.96E-06,5.90E-06,2.00E-06,****,T-test,FCGR3A+ Monocyte LST1,score,HD,Moderate,1.91E-17,5.70E-17,<2e-16,****,T-test,FCGR3A+ Monocyte JUN,score,HD,Moderate,1.46E-17,4.40E-17,<2e-16,****,T-test,FCGR3A+ Monocyte SOD2,score,HD,Moderate,1.39E-06,4.20E-06,1.40E-06,****,T-test,FCGR3A+ Monocyte SMIM25,score,HD,Moderate,1.31E-17,3.90E-17,<2e-16,****,T-test,FCGR3A+ Monocyte NAMPT,score,HD,Moderate,1.23E-24,3.70E-24,<2e-16,****,T-test,FCGR3A+ Monocyte HMOX1,score,HD,Moderate,1.15E-09,3.40E-09,1.10E-09,****,T-test,FCGR3A+ Monocyte PROK2,score,HD,Moderate,0.976340682,1,0.98,ns,T-test,FCGR3A+ Monocyte TCF4,score,HD,Moderate,0.905721574,1,0.91,ns,T-test,FCGR3A+ Monocyte FCER1A,score,HD,Moderate,0.886930012,1,0.89,ns,T-test,FCGR3A+ Monocyte PTGDS,score,HD,Moderate,0.869765903,1,0.87,ns,T-test,FCGR3A+ Monocyte CD1C,score,HD,Moderate,0.828200992,1,0.828,ns,T-test,FCGR3A+ Monocyte IRF8,score,HD,Moderate,0.77535918,1,0.775,ns,T-test,FCGR3A+ Monocyte JCHAIN,score,HD,Moderate,0.748639384,1,0.749,ns,T-test,FCGR3A+ Monocyte GNLY,score,HD,Moderate,0.697978351,1,0.7,ns,T-test,FCGR3A+ Monocyte ALOX5AP,score,HD,Moderate,0.635833044,1,0.636,ns,T-test,FCGR3A+ Monocyte MS4A6A,score,HD,Moderate,0.624210187,1,0.62,ns,T-test,FCGR3A+ Monocyte CLEC10A,score,HD,Moderate,0.552926112,1,0.55,ns,T-test,FCGR3A+ Monocyte CMTM2,score,HD,Moderate,0.510494195,1,0.51,ns,T-test,FCGR3A+ Monocyte SERPINF1,score,HD,Moderate,0.510462157,1,0.51,ns,T-test,FCGR3A+ Monocyte CXCL8,score,HD,Moderate,0.432487429,1,0.43,ns,T-test,FCGR3A+ Monocyte IGKC,score,HD,Moderate,0.395152125,1,0.3952,ns,T-test,FCGR3A+ Monocyte AC020656.1,score,HD,Moderate,0.334106273,1,0.33411,ns,T-test,FCGR3A+ Monocyte NKG7,score,HD,Moderate,0.326737479,0.98,0.33,ns,T-test,FCGR3A+ Monocyte CXCR2,score,HD,Moderate,0.325054211,0.98,0.325,ns,T-test,FCGR3A+ Monocyte PI3,score,HD,Moderate,0.293856498,0.88,0.29,ns,T-test,FCGR3A+ Monocyte TCF7L2,score,HD,Moderate,0.276328917,0.83,0.28,ns,T-test,FCGR3A+ Monocyte ITM2C,score,HD,Moderate,0.242661706,0.73,0.243,ns,T-test,FCGR3A+ Monocyte GZMB,score,HD,Moderate,0.212877939,0.64,0.213,ns,T-test,FCGR3A+ Monocyte GCA,score,HD,Moderate,0.195420426,0.59,0.195,ns,T-test,FCGR3A+ Monocyte PLD4,score,HD,Moderate,0.174623624,0.52,0.17,ns,T-test,FCGR3A+ Monocyte CXCL1,score,HD,Moderate,0.162522041,0.49,0.16,ns,T-test,FCGR3A+ Monocyte HLA-DPA1,score,HD,Moderate,0.160641957,0.48,0.16064,ns,T-test,FCGR3A+ Monocyte S100A12,score,HD,Moderate,0.158867543,0.48,0.16,ns,T-test,FCGR3A+ Monocyte HLA-DRA,score,HD,Moderate,0.148997393,0.45,0.15,ns,T-test,FCGR3A+ Monocyte C12orf75,score,HD,Moderate,0.082635321,0.25,0.08264,ns,T-test,FCGR3A+ Monocyte CD14,score,HD,Moderate,0.073032378,0.22,0.07303,ns,T-test,FCGR3A+ Monocyte HLA-DRB1,score,HD,Moderate,0.065065663,0.2,0.065,ns,T-test,FCGR3A+ Monocyte HLA-DQB1,score,HD,Moderate,0.062714418,0.19,0.0627,ns,T-test,FCGR3A+ Monocyte S100A9,score,HD,Moderate,0.053478271,0.16,0.053,ns,T-test,FCGR3A+ Monocyte IER3,score,HD,Moderate,0.05244934,0.16,0.052,ns,T-test,FCGR3A+ Monocyte CSTA,score,HD,Moderate,0.047460587,0.14,0.0475,*,T-test,FCGR3A+ Monocyte SLC25A37,score,HD,Moderate,0.018004252,0.054,0.018,*,T-test,FCGR3A+ Monocyte IL1B,score,HD,Moderate,0.013437492,0.04,0.0134,*,T-test,FCGR3A+ Monocyte CSF1R,score,HD,Moderate,0.01146298,0.034,0.01146,*,T-test,FCGR3A+ Monocyte S100P,score,HD,Moderate,0.008285647,0.025,0.00829,**,T-test,FCGR3A+ Monocyte FCGR3B,score,HD,Moderate,0.007110726,0.021,0.0071,**,T-test,FCGR3A+ Monocyte CCL5,score,HD,Moderate,0.004951927,0.015,0.005,**,T-test,FCGR3A+ Monocyte S100A8,score,HD,Moderate,0.004238657,0.013,0.0042,**,T-test,FCGR3A+ Monocyte LYPD2,score,HD,Moderate,0.001334977,0.004,0.0013,**,T-test,FCGR3A+ Monocyte CCL3,score,HD,Moderate,0.001147363,0.0034,0.0011,**,T-test,FCGR3A+ Monocyte HLA-DPB1,score,HD,Moderate,0.000709591,0.0021,0.00071,***,T-test,FCGR3A+ Monocyte CD74,score,HD,Moderate,0.00067885,0.002,0.00068,***,T-test,FCGR3A+ Monocyte CDKN1C,score,HD,Moderate,0.000175012,0.00053,0.00018,***,T-test,FCGR3A+ Monocyte LST1,score,Moderate,Severe,8.85E-12,2.70E-11,8.80E-12,****,T-test,Myeloid DC HLA-DPA1,score,Moderate,Severe,8.47E-06,2.50E-05,8.50E-06,****,T-test,Myeloid DC HLA-DQA1,score,Moderate,Severe,7.48E-05,0.00022,7.50E-05,****,T-test,Myeloid DC JUN,score,Moderate,Severe,7.01E-16,2.10E-15,7.00E-16,****,T-test,Myeloid DC IL1B,score,Moderate,Severe,6.31E-05,0.00019,6.30E-05,****,T-test,Myeloid DC CSTA,score,Moderate,Severe,5.88E-11,1.80E-10,5.90E-11,****,T-test,Myeloid DC HLA-DQB1,score,Moderate,Severe,5.47E-06,1.60E-05,5.50E-06,****,T-test,Myeloid DC GNLY,score,Moderate,Severe,3.22E-06,9.70E-06,3.20E-06,****,T-test,Myeloid DC PPBP,score,Moderate,Severe,2.86E-09,8.60E-09,2.90E-09,****,T-test,Myeloid DC CCL5,score,Moderate,Severe,2.65E-07,8.00E-07,2.70E-07,****,T-test,Myeloid DC GCA,score,Moderate,Severe,2.57E-06,7.70E-06,2.60E-06,****,T-test,Myeloid DC HLA-DRB1,score,Moderate,Severe,2.40E-05,7.20E-05,2.40E-05,****,T-test,Myeloid DC AC020656.1,score,Moderate,Severe,2.22E-09,6.70E-09,2.20E-09,****,T-test,Myeloid DC HLA-DPB1,score,Moderate,Severe,1.61E-06,4.80E-06,1.60E-06,****,T-test,Myeloid DC CCL3L1,score,Moderate,Severe,1.20E-07,3.60E-07,1.20E-07,****,T-test,Myeloid DC NKG7,score,Moderate,Severe,1.02E-05,3.10E-05,1.00E-05,****,T-test,Myeloid DC PTGDS,score,Moderate,Severe,0.779133208,1,0.78,ns,T-test,Myeloid DC CDKN1C,score,Moderate,Severe,0.689011906,1,0.69,ns,T-test,Myeloid DC TCF7L2,score,Moderate,Severe,0.685166835,1,0.69,ns,T-test,Myeloid DC CMTM2,score,Moderate,Severe,0.652075798,1,0.65,ns,T-test,Myeloid DC SOD2,score,Moderate,Severe,0.650999557,1,0.65,ns,T-test,Myeloid DC PROK2,score,Moderate,Severe,0.636544684,1,0.637,ns,T-test,Myeloid DC JCHAIN,score,Moderate,Severe,0.623288682,1,0.623,ns,T-test,Myeloid DC IRF7,score,Moderate,Severe,0.609468519,1,0.6095,ns,T-test,Myeloid DC HLA-DRA,score,Moderate,Severe,0.582868379,1,0.5829,ns,T-test,Myeloid DC MS4A7,score,Moderate,Severe,0.568120195,1,0.568,ns,T-test,Myeloid DC CD36,score,Moderate,Severe,0.564122954,1,0.5641,ns,T-test,Myeloid DC G0S2,score,Moderate,Severe,0.483030542,1,0.48,ns,T-test,Myeloid DC IFITM3,score,Moderate,Severe,0.352560814,1,0.35,ns,T-test,Myeloid DC S100A9,score,Moderate,Severe,0.303224972,0.91,0.3,ns,T-test,Myeloid DC SERPINA1,score,Moderate,Severe,0.27526323,0.83,0.28,ns,T-test,Myeloid DC LYZ,score,Moderate,Severe,0.247440296,0.74,0.25,ns,T-test,Myeloid DC S100A8,score,Moderate,Severe,0.198122914,0.59,0.2,ns,T-test,Myeloid DC PI3,score,Moderate,Severe,0.175024852,0.35,0.18,ns,T-test,Myeloid DC HMOX1,score,Moderate,Severe,0.174634985,0.52,0.17463,ns,T-test,Myeloid DC CXCL1,score,Moderate,Severe,0.170004368,0.51,0.17,ns,T-test,Myeloid DC LYPD2,score,Moderate,Severe,0.16937407,0.51,0.17,ns,T-test,Myeloid DC FCGR3B,score,Moderate,Severe,0.161237603,0.48,0.16,ns,T-test,Myeloid DC VCAN,score,Moderate,Severe,0.132444552,0.4,0.132,ns,T-test,Myeloid DC C12orf75,score,Moderate,Severe,0.130227106,0.39,0.13,ns,T-test,Myeloid DC SERPINF1,score,Moderate,Severe,0.125266754,0.38,0.125,ns,T-test,Myeloid DC RHOC,score,Moderate,Severe,0.109508441,0.33,0.1095,ns,T-test,Myeloid DC MS4A6A,score,Moderate,Severe,0.102373465,0.31,0.1024,ns,T-test,Myeloid DC SLC25A37,score,Moderate,Severe,0.083785417,0.25,0.084,ns,T-test,Myeloid DC S100A12,score,Moderate,Severe,0.081638112,0.24,0.082,ns,T-test,Myeloid DC ITM2C,score,Moderate,Severe,0.071128172,0.21,0.07113,ns,T-test,Myeloid DC CD14,score,Moderate,Severe,0.059227153,0.18,0.05923,ns,T-test,Myeloid DC S100P,score,Moderate,Severe,0.051023411,0.15,0.051,ns,T-test,Myeloid DC CXCR2,score,Moderate,Severe,0.036348729,0.11,0.036,*,T-test,Myeloid DC IFITM2,score,Moderate,Severe,0.022128286,0.066,0.022,*,T-test,Myeloid DC FCGR3A,score,Moderate,Severe,0.020444358,0.061,0.02,*,T-test,Myeloid DC CXCL8,score,Moderate,Severe,0.020242227,0.061,0.0202,*,T-test,Myeloid DC SMIM25,score,Moderate,Severe,0.018769504,0.056,0.01877,*,T-test,Myeloid DC IGKC,score,Moderate,Severe,0.017682485,0.053,0.018,*,T-test,Myeloid DC ALOX5AP,score,Moderate,Severe,0.012554091,0.038,0.013,*,T-test,Myeloid DC CCL3,score,Moderate,Severe,0.012370589,0.037,0.012,*,T-test,Myeloid DC NAMPT,score,Moderate,Severe,0.010685936,0.032,0.011,*,T-test,Myeloid DC TCF4,score,Moderate,Severe,0.007512575,0.023,0.0075,**,T-test,Myeloid DC IER3,score,Moderate,Severe,0.005425528,0.016,0.0054,**,T-test,Myeloid DC FCER1A,score,Moderate,Severe,0.004450631,0.013,0.0045,**,T-test,Myeloid DC CD74,score,Moderate,Severe,0.003153008,0.0095,0.0032,**,T-test,Myeloid DC CD1C,score,Moderate,Severe,0.002648257,0.0079,0.00265,**,T-test,Myeloid DC IRF8,score,Moderate,Severe,0.002135882,0.0064,0.00214,**,T-test,Myeloid DC WARS,score,Moderate,Severe,0.00141288,0.0042,0.0014,**,T-test,Myeloid DC GZMB,score,Moderate,Severe,0.001299749,0.0039,0.0013,**,T-test,Myeloid DC CLEC10A,score,Moderate,Severe,0.001105703,0.0033,0.0011,**,T-test,Myeloid DC CSF1R,score,Moderate,Severe,0.001032822,0.0031,0.001,**,T-test,Myeloid DC IFITM1,score,Moderate,Severe,0.000364073,0.0011,0.00036,***,T-test,Myeloid DC PLD4,score,Moderate,Severe,0.000156529,0.00047,0.00016,***,T-test,Myeloid DC PLD4,score,HD,Severe,9.44E-06,2.80E-05,9.40E-06,****,T-test,Myeloid DC AC020656.1,score,HD,Severe,8.29E-08,2.50E-07,8.30E-08,****,T-test,Myeloid DC IFITM3,score,HD,Severe,8.17E-16,2.50E-15,8.20E-16,****,T-test,Myeloid DC SERPINA1,score,HD,Severe,6.90E-10,2.10E-09,6.90E-10,****,T-test,Myeloid DC CCL5,score,HD,Severe,6.61E-08,2.00E-07,6.60E-08,****,T-test,Myeloid DC IFITM2,score,HD,Severe,5.14E-06,1.50E-05,5.10E-06,****,T-test,Myeloid DC CCL3,score,HD,Severe,4.43E-16,1.30E-15,4.40E-16,****,T-test,Myeloid DC LST1,score,HD,Severe,4.37E-15,1.30E-14,4.40E-15,****,T-test,Myeloid DC IRF7,score,HD,Severe,3.55E-05,0.00011,3.50E-05,****,T-test,Myeloid DC LYZ,score,HD,Severe,2.86E-23,8.60E-23,<2e-16,****,T-test,Myeloid DC HLA-DQB1,score,HD,Severe,2.76E-05,8.30E-05,2.80E-05,****,T-test,Myeloid DC NKG7,score,HD,Severe,2.35E-05,7.00E-05,2.30E-05,****,T-test,Myeloid DC GNLY,score,HD,Severe,1.98E-05,5.90E-05,2.00E-05,****,T-test,Myeloid DC NAMPT,score,HD,Severe,1.93E-06,5.80E-06,1.90E-06,****,T-test,Myeloid DC IER3,score,HD,Severe,1.54E-07,4.60E-07,1.50E-07,****,T-test,Myeloid DC CSTA,score,HD,Severe,1.53E-15,4.60E-15,1.50E-15,****,T-test,Myeloid DC FCER1A,score,HD,Severe,1.49E-07,4.50E-07,1.50E-07,****,T-test,Myeloid DC HLA-DRB1,score,HD,Severe,1.37E-14,4.10E-14,1.40E-14,****,T-test,Myeloid DC CCL3L1,score,HD,Severe,1.37E-28,4.10E-28,< 2e-16,****,T-test,Myeloid DC CD74,score,HD,Severe,1.34E-06,4.00E-06,1.30E-06,****,T-test,Myeloid DC JUN,score,HD,Severe,1.05E-08,3.20E-08,1.10E-08,****,T-test,Myeloid DC GZMB,score,HD,Severe,0.97996643,1,0.98,ns,T-test,Myeloid DC ALOX5AP,score,HD,Severe,0.926132151,1,0.926,ns,T-test,Myeloid DC FCGR3A,score,HD,Severe,0.901208318,1,0.901,ns,T-test,Myeloid DC S100P,score,HD,Severe,0.829995199,1,0.83,ns,T-test,Myeloid DC LYPD2,score,HD,Severe,0.821818941,1,0.82,ns,T-test,Myeloid DC CMTM2,score,HD,Severe,0.706340381,1,0.71,ns,T-test,Myeloid DC PTGDS,score,HD,Severe,0.690400914,1,0.69,ns,T-test,Myeloid DC C12orf75,score,HD,Severe,0.649616037,1,0.65,ns,T-test,Myeloid DC SOD2,score,HD,Severe,0.630495365,1,0.63,ns,T-test,Myeloid DC S100A9,score,HD,Severe,0.548868918,1,0.55,ns,T-test,Myeloid DC VCAN,score,HD,Severe,0.531942975,1,0.532,ns,T-test,Myeloid DC CXCL1,score,HD,Severe,0.505420218,1,0.51,ns,T-test,Myeloid DC CDKN1C,score,HD,Severe,0.475765072,1,0.48,ns,T-test,Myeloid DC IGKC,score,HD,Severe,0.472454055,1,0.472,ns,T-test,Myeloid DC FCGR3B,score,HD,Severe,0.318085433,0.95,0.32,ns,T-test,Myeloid DC CXCR2,score,HD,Severe,0.276282007,0.83,0.276,ns,T-test,Myeloid DC S100A8,score,HD,Severe,0.259134987,0.78,0.26,ns,T-test,Myeloid DC CLEC10A,score,HD,Severe,0.253190996,0.76,0.2532,ns,T-test,Myeloid DC TCF4,score,HD,Severe,0.240773167,0.72,0.2408,ns,T-test,Myeloid DC TCF7L2,score,HD,Severe,0.234600367,0.7,0.23,ns,T-test,Myeloid DC PI3,score,HD,Severe,0.175024852,0.35,0.18,ns,T-test,Myeloid DC G0S2,score,HD,Severe,0.17060361,0.51,0.17,ns,T-test,Myeloid DC CXCL8,score,HD,Severe,0.164581456,0.49,0.1646,ns,T-test,Myeloid DC IFITM1,score,HD,Severe,0.097153283,0.29,0.09715,ns,T-test,Myeloid DC S100A12,score,HD,Severe,0.077992091,0.23,0.078,ns,T-test,Myeloid DC SMIM25,score,HD,Severe,0.073618359,0.22,0.07362,ns,T-test,Myeloid DC PPBP,score,HD,Severe,0.072718827,0.22,0.0727,ns,T-test,Myeloid DC JCHAIN,score,HD,Severe,0.07263001,0.22,0.073,ns,T-test,Myeloid DC HLA-DPA1,score,HD,Severe,0.062975456,0.19,0.063,ns,T-test,Myeloid DC HLA-DPB1,score,HD,Severe,0.061554906,0.18,0.062,ns,T-test,Myeloid DC PROK2,score,HD,Severe,0.035326682,0.11,0.035,*,T-test,Myeloid DC GCA,score,HD,Severe,0.02275197,0.068,0.023,*,T-test,Myeloid DC SLC25A37,score,HD,Severe,0.021364806,0.064,0.021,*,T-test,Myeloid DC MS4A7,score,HD,Severe,0.020778593,0.062,0.021,*,T-test,Myeloid DC SERPINF1,score,HD,Severe,0.013937463,0.042,0.014,*,T-test,Myeloid DC HLA-DRA,score,HD,Severe,0.010437692,0.031,0.0104,*,T-test,Myeloid DC RHOC,score,HD,Severe,0.009360366,0.028,0.0094,**,T-test,Myeloid DC CSF1R,score,HD,Severe,0.008635233,0.026,0.0086,**,T-test,Myeloid DC MS4A6A,score,HD,Severe,0.004862173,0.015,0.0049,**,T-test,Myeloid DC CD36,score,HD,Severe,0.001974744,0.0059,0.002,**,T-test,Myeloid DC WARS,score,HD,Severe,0.001105802,0.0033,0.0011,**,T-test,Myeloid DC IL1B,score,HD,Severe,0.000879941,0.0026,0.00088,***,T-test,Myeloid DC ITM2C,score,HD,Severe,0.000248498,0.00075,0.00025,***,T-test,Myeloid DC CD14,score,HD,Severe,0.000192535,0.00058,0.00019,***,T-test,Myeloid DC IRF8,score,HD,Severe,0.000149713,0.00045,0.00015,***,T-test,Myeloid DC HLA-DQA1,score,HD,Severe,0.00013612,0.00041,0.00014,***,T-test,Myeloid DC CD1C,score,HD,Severe,0.000107541,0.00032,0.00011,***,T-test,Myeloid DC HMOX1,score,HD,Severe,0.00010563,0.00032,0.00011,***,T-test,Myeloid DC HLA-DRB1,score,HD,Moderate,9.93E-05,3.00E-04,9.90E-05,****,T-test,Myeloid DC IER3,score,HD,Moderate,6.77E-12,2.00E-11,6.80E-12,****,T-test,Myeloid DC CCL3L1,score,HD,Moderate,6.61E-40,2.00E-39,< 2e-16,****,T-test,Myeloid DC HMOX1,score,HD,Moderate,5.30E-06,1.60E-05,5.30E-06,****,T-test,Myeloid DC CCL3,score,HD,Moderate,5.18E-20,1.60E-19,< 2e-16,****,T-test,Myeloid DC IFITM3,score,HD,Moderate,4.15E-16,1.20E-15,4.10E-16,****,T-test,Myeloid DC IL1B,score,HD,Moderate,2.56E-09,7.70E-09,2.60E-09,****,T-test,Myeloid DC SERPINA1,score,HD,Moderate,1.74E-06,5.20E-06,1.70E-06,****,T-test,Myeloid DC NAMPT,score,HD,Moderate,1.58E-10,4.70E-10,1.60E-10,****,T-test,Myeloid DC LYZ,score,HD,Moderate,1.20E-29,3.60E-29,<2e-16,****,T-test,Myeloid DC JUN,score,HD,Moderate,1.05E-27,3.20E-27,< 2e-16,****,T-test,Myeloid DC S100A8,score,HD,Moderate,0.984514207,1,0.98,ns,T-test,Myeloid DC GNLY,score,HD,Moderate,0.96624293,1,0.97,ns,T-test,Myeloid DC AC020656.1,score,HD,Moderate,0.963368066,1,0.96,ns,T-test,Myeloid DC CMTM2,score,HD,Moderate,0.928900691,1,0.93,ns,T-test,Myeloid DC PTGDS,score,HD,Moderate,0.890387998,1,0.89,ns,T-test,Myeloid DC NKG7,score,HD,Moderate,0.881043753,1,0.88,ns,T-test,Myeloid DC HLA-DQA1,score,HD,Moderate,0.877423976,1,0.87742,ns,T-test,Myeloid DC S100A12,score,HD,Moderate,0.869746883,1,0.87,ns,T-test,Myeloid DC CSF1R,score,HD,Moderate,0.801360841,1,0.8014,ns,T-test,Myeloid DC HLA-DQB1,score,HD,Moderate,0.74534337,1,0.75,ns,T-test,Myeloid DC WARS,score,HD,Moderate,0.696330804,1,0.6963,ns,T-test,Myeloid DC CXCR2,score,HD,Moderate,0.658359884,1,0.658,ns,T-test,Myeloid DC CCL5,score,HD,Moderate,0.568743924,1,0.57,ns,T-test,Myeloid DC SLC25A37,score,HD,Moderate,0.476672623,1,0.477,ns,T-test,Myeloid DC G0S2,score,HD,Moderate,0.458266481,1,0.46,ns,T-test,Myeloid DC SOD2,score,HD,Moderate,0.418175562,1,0.42,ns,T-test,Myeloid DC FCGR3B,score,HD,Moderate,0.401800152,1,0.4,ns,T-test,Myeloid DC SERPINF1,score,HD,Moderate,0.36882234,1,0.369,ns,T-test,Myeloid DC IRF8,score,HD,Moderate,0.362260174,1,0.36226,ns,T-test,Myeloid DC PLD4,score,HD,Moderate,0.34578939,1,0.34579,ns,T-test,Myeloid DC CDKN1C,score,HD,Moderate,0.339892547,1,0.34,ns,T-test,Myeloid DC LYPD2,score,HD,Moderate,0.318085433,0.95,0.32,ns,T-test,Myeloid DC CXCL1,score,HD,Moderate,0.318085433,0.95,0.32,ns,T-test,Myeloid DC CD1C,score,HD,Moderate,0.311427034,0.93,0.31143,ns,T-test,Myeloid DC RHOC,score,HD,Moderate,0.30019873,0.9,0.3002,ns,T-test,Myeloid DC CD74,score,HD,Moderate,0.297628895,0.89,0.2976,ns,T-test,Myeloid DC TCF4,score,HD,Moderate,0.240942419,0.72,0.2409,ns,T-test,Myeloid DC MS4A6A,score,HD,Moderate,0.211671876,0.64,0.2117,ns,T-test,Myeloid DC IGKC,score,HD,Moderate,0.207146928,0.62,0.207,ns,T-test,Myeloid DC LST1,score,HD,Moderate,0.198040272,0.59,0.2,ns,T-test,Myeloid DC IFITM1,score,HD,Moderate,0.184827956,0.55,0.18483,ns,T-test,Myeloid DC S100P,score,HD,Moderate,0.176656633,0.53,0.177,ns,T-test,Myeloid DC S100A9,score,HD,Moderate,0.170952808,0.51,0.17,ns,T-test,Myeloid DC JCHAIN,score,HD,Moderate,0.158456281,0.48,0.158,ns,T-test,Myeloid DC TCF7L2,score,HD,Moderate,0.144883092,0.43,0.14,ns,T-test,Myeloid DC PROK2,score,HD,Moderate,0.118490419,0.36,0.118,ns,T-test,Myeloid DC CLEC10A,score,HD,Moderate,0.108677973,0.33,0.1087,ns,T-test,Myeloid DC MS4A7,score,HD,Moderate,0.096021819,0.29,0.096,ns,T-test,Myeloid DC C12orf75,score,HD,Moderate,0.092043166,0.28,0.092,ns,T-test,Myeloid DC HLA-DPA1,score,HD,Moderate,0.083914241,0.25,0.084,ns,T-test,Myeloid DC VCAN,score,HD,Moderate,0.072801312,0.22,0.073,ns,T-test,Myeloid DC CSTA,score,HD,Moderate,0.071801649,0.22,0.072,ns,T-test,Myeloid DC FCGR3A,score,HD,Moderate,0.063333024,0.19,0.063,ns,T-test,Myeloid DC GCA,score,HD,Moderate,0.061777257,0.19,0.062,ns,T-test,Myeloid DC ITM2C,score,HD,Moderate,0.055997587,0.17,0.056,ns,T-test,Myeloid DC HLA-DPB1,score,HD,Moderate,0.046949775,0.14,0.047,*,T-test,Myeloid DC CD14,score,HD,Moderate,0.045145552,0.14,0.04515,*,T-test,Myeloid DC ALOX5AP,score,HD,Moderate,0.038480327,0.12,0.038,*,T-test,Myeloid DC IFITM2,score,HD,Moderate,0.019473371,0.058,0.019,*,T-test,Myeloid DC GZMB,score,HD,Moderate,0.013630662,0.041,0.0136,*,T-test,Myeloid DC FCER1A,score,HD,Moderate,0.009017834,0.027,0.009,**,T-test,Myeloid DC HLA-DRA,score,HD,Moderate,0.008887771,0.027,0.0089,**,T-test,Myeloid DC CXCL8,score,HD,Moderate,0.003884846,0.012,0.0039,**,T-test,Myeloid DC PPBP,score,HD,Moderate,0.002585722,0.0078,0.0026,**,T-test,Myeloid DC CD36,score,HD,Moderate,0.001195268,0.0036,0.0012,**,T-test,Myeloid DC IRF7,score,HD,Moderate,0.000601284,0.0018,0.0006,***,T-test,Myeloid DC SMIM25,score,HD,Moderate,0.000587113,0.0018,0.00059,***,T-test,Myeloid DC FCGR3B,score,Moderate,Severe,5.10E-14,1.50E-13,5.10E-14,****,T-test,Neutrophil S100A12,score,Moderate,Severe,3.88E-19,1.20E-18,< 2e-16,****,T-test,Neutrophil SLC25A37,score,Moderate,Severe,3.51E-07,1.10E-06,3.50E-07,****,T-test,Neutrophil JUN,score,Moderate,Severe,3.34E-06,1.00E-05,3.30E-06,****,T-test,Neutrophil CXCL8,score,Moderate,Severe,1.61E-08,4.80E-08,1.60E-08,****,T-test,Neutrophil G0S2,score,Moderate,Severe,1.34E-07,4.00E-07,1.30E-07,****,T-test,Neutrophil HLA-DPB1,score,Moderate,Severe,0.987947256,1,0.99,ns,T-test,Neutrophil TCF7L2,score,Moderate,Severe,0.971706247,1,0.97,ns,T-test,Neutrophil S100A9,score,Moderate,Severe,0.954093351,1,0.954,ns,T-test,Neutrophil CD36,score,Moderate,Severe,0.92930562,1,0.93,ns,T-test,Neutrophil PLD4,score,Moderate,Severe,0.904604016,1,0.905,ns,T-test,Neutrophil MS4A7,score,Moderate,Severe,0.873491646,1,0.873,ns,T-test,Neutrophil CD14,score,Moderate,Severe,0.870656031,1,0.87,ns,T-test,Neutrophil AC020656.1,score,Moderate,Severe,0.805280258,1,0.81,ns,T-test,Neutrophil CCL5,score,Moderate,Severe,0.676466059,1,0.676,ns,T-test,Neutrophil CSF1R,score,Moderate,Severe,0.668496638,1,0.67,ns,T-test,Neutrophil CD1C,score,Moderate,Severe,0.658412797,1,0.66,ns,T-test,Neutrophil HLA-DRA,score,Moderate,Severe,0.645415937,1,0.65,ns,T-test,Neutrophil CD74,score,Moderate,Severe,0.581974799,1,0.58,ns,T-test,Neutrophil IRF7,score,Moderate,Severe,0.506862047,1,0.51,ns,T-test,Neutrophil HLA-DQB1,score,Moderate,Severe,0.501930142,1,0.5,ns,T-test,Neutrophil IER3,score,Moderate,Severe,0.482006722,1,0.48201,ns,T-test,Neutrophil CCL3L1,score,Moderate,Severe,0.472765165,1,0.47,ns,T-test,Neutrophil CDKN1C,score,Moderate,Severe,0.456286135,1,0.46,ns,T-test,Neutrophil HLA-DQA1,score,Moderate,Severe,0.429587404,1,0.43,ns,T-test,Neutrophil SERPINA1,score,Moderate,Severe,0.414486562,1,0.41,ns,T-test,Neutrophil IRF8,score,Moderate,Severe,0.409952367,1,0.41,ns,T-test,Neutrophil CCL3,score,Moderate,Severe,0.407499663,1,0.41,ns,T-test,Neutrophil RHOC,score,Moderate,Severe,0.386086688,1,0.39,ns,T-test,Neutrophil CLEC10A,score,Moderate,Severe,0.351585018,1,0.35,ns,T-test,Neutrophil LYPD2,score,Moderate,Severe,0.318025868,0.64,0.32,ns,T-test,Neutrophil WARS,score,Moderate,Severe,0.295353842,0.89,0.2954,ns,T-test,Neutrophil NAMPT,score,Moderate,Severe,0.288401014,0.87,0.2884,ns,T-test,Neutrophil HLA-DRB1,score,Moderate,Severe,0.284858001,0.85,0.28,ns,T-test,Neutrophil IFITM3,score,Moderate,Severe,0.260642648,0.78,0.261,ns,T-test,Neutrophil FCGR3A,score,Moderate,Severe,0.251812539,0.76,0.2518,ns,T-test,Neutrophil IFITM2,score,Moderate,Severe,0.235447705,0.71,0.235,ns,T-test,Neutrophil PI3,score,Moderate,Severe,0.216848497,0.65,0.2168,ns,T-test,Neutrophil LST1,score,Moderate,Severe,0.215360443,0.65,0.22,ns,T-test,Neutrophil VCAN,score,Moderate,Severe,0.196426489,0.59,0.196,ns,T-test,Neutrophil SMIM25,score,Moderate,Severe,0.183985704,0.55,0.18399,ns,T-test,Neutrophil PPBP,score,Moderate,Severe,0.182297902,0.55,0.1823,ns,T-test,Neutrophil PROK2,score,Moderate,Severe,0.169220421,0.51,0.17,ns,T-test,Neutrophil NKG7,score,Moderate,Severe,0.161624576,0.48,0.162,ns,T-test,Neutrophil TCF4,score,Moderate,Severe,0.160841589,0.48,0.161,ns,T-test,Neutrophil FCER1A,score,Moderate,Severe,0.157639838,0.32,0.16,ns,T-test,Neutrophil SERPINF1,score,Moderate,Severe,0.15746437,0.31,0.16,ns,T-test,Neutrophil CMTM2,score,Moderate,Severe,0.135739886,0.41,0.136,ns,T-test,Neutrophil IL1B,score,Moderate,Severe,0.121221067,0.36,0.12,ns,T-test,Neutrophil S100P,score,Moderate,Severe,0.104455583,0.31,0.1,ns,T-test,Neutrophil IGKC,score,Moderate,Severe,0.10092274,0.3,0.101,ns,T-test,Neutrophil CSTA,score,Moderate,Severe,0.098874861,0.3,0.099,ns,T-test,Neutrophil HMOX1,score,Moderate,Severe,0.098735505,0.3,0.099,ns,T-test,Neutrophil GNLY,score,Moderate,Severe,0.098016461,0.29,0.098,ns,T-test,Neutrophil CXCL1,score,Moderate,Severe,0.076265388,0.23,0.076,ns,T-test,Neutrophil GZMB,score,Moderate,Severe,0.074329599,0.22,0.074,ns,T-test,Neutrophil SOD2,score,Moderate,Severe,0.062206647,0.19,0.062,ns,T-test,Neutrophil ITM2C,score,Moderate,Severe,0.058338448,0.18,0.058,ns,T-test,Neutrophil HLA-DPA1,score,Moderate,Severe,0.058336641,0.18,0.058,ns,T-test,Neutrophil LYZ,score,Moderate,Severe,0.045379829,0.14,0.0454,*,T-test,Neutrophil PTGDS,score,Moderate,Severe,0.035349878,0.11,0.035,*,T-test,Neutrophil JCHAIN,score,Moderate,Severe,0.018522812,0.056,0.0185,*,T-test,Neutrophil IFITM1,score,Moderate,Severe,0.012329483,0.037,0.012,*,T-test,Neutrophil MS4A6A,score,Moderate,Severe,0.009792327,0.029,0.0098,**,T-test,Neutrophil ALOX5AP,score,Moderate,Severe,0.009553821,0.029,0.0096,**,T-test,Neutrophil GCA,score,Moderate,Severe,0.003914456,0.012,0.0039,**,T-test,Neutrophil CXCR2,score,Moderate,Severe,0.00311193,0.0093,0.0031,**,T-test,Neutrophil S100A8,score,Moderate,Severe,0.002043909,0.0061,0.00204,**,T-test,Neutrophil C12orf75,score,Moderate,Severe,0.000339461,0.001,0.00034,***,T-test,Neutrophil CXCL8,score,HD,Severe,9.10E-11,2.70E-10,9.10E-11,****,T-test,Neutrophil S100A12,score,HD,Severe,5.89E-05,0.00018,5.90E-05,****,T-test,Neutrophil S100P,score,HD,Severe,3.87E-08,1.20E-07,3.90E-08,****,T-test,Neutrophil IER3,score,HD,Severe,2.64E-05,7.90E-05,2.60E-05,****,T-test,Neutrophil G0S2,score,HD,Severe,1.15E-08,3.40E-08,1.10E-08,****,T-test,Neutrophil CSTA,score,HD,Severe,0.985927707,1,0.986,ns,T-test,Neutrophil JUN,score,HD,Severe,0.982162978,1,0.98216,ns,T-test,Neutrophil PTGDS,score,HD,Severe,0.930979482,1,0.931,ns,T-test,Neutrophil HMOX1,score,HD,Severe,0.885324323,1,0.885,ns,T-test,Neutrophil CSF1R,score,HD,Severe,0.879858965,1,0.88,ns,T-test,Neutrophil SERPINA1,score,HD,Severe,0.872518595,1,0.87,ns,T-test,Neutrophil IFITM1,score,HD,Severe,0.850396253,1,0.85,ns,T-test,Neutrophil IRF8,score,HD,Severe,0.736831534,1,0.74,ns,T-test,Neutrophil CXCR2,score,HD,Severe,0.708290507,1,0.7083,ns,T-test,Neutrophil AC020656.1,score,HD,Severe,0.703244121,1,0.7,ns,T-test,Neutrophil HLA-DRB1,score,HD,Severe,0.697979562,1,0.7,ns,T-test,Neutrophil CDKN1C,score,HD,Severe,0.682218946,1,0.68,ns,T-test,Neutrophil CCL3,score,HD,Severe,0.647980673,1,0.65,ns,T-test,Neutrophil GZMB,score,HD,Severe,0.613962747,1,0.614,ns,T-test,Neutrophil ITM2C,score,HD,Severe,0.604323576,1,0.604,ns,T-test,Neutrophil CD14,score,HD,Severe,0.603221019,1,0.6,ns,T-test,Neutrophil HLA-DPA1,score,HD,Severe,0.576001595,1,0.576,ns,T-test,Neutrophil CXCL1,score,HD,Severe,0.575673733,1,0.576,ns,T-test,Neutrophil GNLY,score,HD,Severe,0.548144862,1,0.548,ns,T-test,Neutrophil CD74,score,HD,Severe,0.522247635,1,0.52,ns,T-test,Neutrophil PROK2,score,HD,Severe,0.513005563,1,0.51,ns,T-test,Neutrophil CLEC10A,score,HD,Severe,0.508489673,1,0.51,ns,T-test,Neutrophil HLA-DQB1,score,HD,Severe,0.500635703,1,0.5,ns,T-test,Neutrophil FCGR3B,score,HD,Severe,0.493383565,1,0.49,ns,T-test,Neutrophil CD1C,score,HD,Severe,0.484028235,1,0.48,ns,T-test,Neutrophil VCAN,score,HD,Severe,0.472107453,1,0.472,ns,T-test,Neutrophil HLA-DPB1,score,HD,Severe,0.458680823,1,0.46,ns,T-test,Neutrophil MS4A6A,score,HD,Severe,0.43445151,1,0.4345,ns,T-test,Neutrophil SLC25A37,score,HD,Severe,0.424519925,1,0.42,ns,T-test,Neutrophil CCL3L1,score,HD,Severe,0.423975878,1,0.42,ns,T-test,Neutrophil TCF7L2,score,HD,Severe,0.381059066,1,0.38,ns,T-test,Neutrophil RHOC,score,HD,Severe,0.359197464,1,0.36,ns,T-test,Neutrophil HLA-DRA,score,HD,Severe,0.356462449,1,0.36,ns,T-test,Neutrophil IRF7,score,HD,Severe,0.329591975,0.99,0.33,ns,T-test,Neutrophil HLA-DQA1,score,HD,Severe,0.304070628,0.91,0.3,ns,T-test,Neutrophil CD36,score,HD,Severe,0.273697254,0.82,0.27,ns,T-test,Neutrophil IGKC,score,HD,Severe,0.267459552,0.8,0.267,ns,T-test,Neutrophil S100A8,score,HD,Severe,0.265923092,0.8,0.26592,ns,T-test,Neutrophil LST1,score,HD,Severe,0.258765412,0.78,0.26,ns,T-test,Neutrophil ALOX5AP,score,HD,Severe,0.24853372,0.75,0.2485,ns,T-test,Neutrophil TCF4,score,HD,Severe,0.175937936,0.53,0.176,ns,T-test,Neutrophil SERPINF1,score,HD,Severe,0.15746437,0.31,0.16,ns,T-test,Neutrophil LYZ,score,HD,Severe,0.141852729,0.43,0.1419,ns,T-test,Neutrophil SOD2,score,HD,Severe,0.13645978,0.41,0.136,ns,T-test,Neutrophil IL1B,score,HD,Severe,0.10722511,0.32,0.11,ns,T-test,Neutrophil PLD4,score,HD,Severe,0.083297578,0.25,0.083,ns,T-test,Neutrophil IFITM3,score,HD,Severe,0.073605882,0.22,0.074,ns,T-test,Neutrophil IFITM2,score,HD,Severe,0.061212196,0.18,0.061,ns,T-test,Neutrophil JCHAIN,score,HD,Severe,0.045708714,0.14,0.0457,*,T-test,Neutrophil CCL5,score,HD,Severe,0.043602841,0.13,0.044,*,T-test,Neutrophil S100A9,score,HD,Severe,0.031334689,0.094,0.031,*,T-test,Neutrophil MS4A7,score,HD,Severe,0.025220282,0.076,0.025,*,T-test,Neutrophil C12orf75,score,HD,Severe,0.010808918,0.032,0.01081,*,T-test,Neutrophil NKG7,score,HD,Severe,0.010710082,0.032,0.011,*,T-test,Neutrophil FCGR3A,score,HD,Severe,0.005848926,0.018,0.0058,**,T-test,Neutrophil PPBP,score,HD,Severe,0.005776513,0.017,0.0058,**,T-test,Neutrophil GCA,score,HD,Severe,0.004874708,0.015,0.0049,**,T-test,Neutrophil WARS,score,HD,Severe,0.004318273,0.013,0.0043,**,T-test,Neutrophil PI3,score,HD,Severe,0.002501256,0.0075,0.0025,**,T-test,Neutrophil CMTM2,score,HD,Severe,0.002029413,0.0061,0.002,**,T-test,Neutrophil NAMPT,score,HD,Severe,0.000178657,0.00054,0.00018,***,T-test,Neutrophil SMIM25,score,HD,Severe,0.000108715,0.00033,0.00011,***,T-test,Neutrophil CMTM2,score,HD,Moderate,8.11E-05,0.00024,8.10E-05,****,T-test,Neutrophil G0S2,score,HD,Moderate,4.14E-20,1.20E-19,< 2e-16,****,T-test,Neutrophil SLC25A37,score,HD,Moderate,3.91E-06,1.20E-05,3.90E-06,****,T-test,Neutrophil S100P,score,HD,Moderate,3.54E-05,0.00011,3.50E-05,****,T-test,Neutrophil FCGR3B,score,HD,Moderate,2.99E-11,9.00E-11,3.00E-11,****,T-test,Neutrophil NAMPT,score,HD,Moderate,2.31E-05,6.90E-05,2.30E-05,****,T-test,Neutrophil CXCL8,score,HD,Moderate,2.04E-24,6.10E-24,< 2e-16,****,T-test,Neutrophil CLEC10A,score,HD,Moderate,0.956894937,1,0.96,ns,T-test,Neutrophil SOD2,score,HD,Moderate,0.954787421,1,0.955,ns,T-test,Neutrophil LST1,score,HD,Moderate,0.941658151,1,0.94,ns,T-test,Neutrophil CDKN1C,score,HD,Moderate,0.820575922,1,0.82,ns,T-test,Neutrophil CCL3,score,HD,Moderate,0.8146843,1,0.81,ns,T-test,Neutrophil IL1B,score,HD,Moderate,0.753327966,1,0.75,ns,T-test,Neutrophil GCA,score,HD,Moderate,0.721923929,1,0.7219,ns,T-test,Neutrophil CD1C,score,HD,Moderate,0.687301238,1,0.69,ns,T-test,Neutrophil HLA-DRB1,score,HD,Moderate,0.640483098,1,0.64,ns,T-test,Neutrophil SERPINA1,score,HD,Moderate,0.636420327,1,0.64,ns,T-test,Neutrophil CSF1R,score,HD,Moderate,0.62888964,1,0.63,ns,T-test,Neutrophil HLA-DRA,score,HD,Moderate,0.618185643,1,0.62,ns,T-test,Neutrophil C12orf75,score,HD,Moderate,0.617502085,1,0.6175,ns,T-test,Neutrophil AC020656.1,score,HD,Moderate,0.591857034,1,0.59,ns,T-test,Neutrophil CD14,score,HD,Moderate,0.550450383,1,0.55,ns,T-test,Neutrophil HLA-DPB1,score,HD,Moderate,0.49697979,1,0.5,ns,T-test,Neutrophil TCF7L2,score,HD,Moderate,0.426802209,1,0.43,ns,T-test,Neutrophil CXCL1,score,HD,Moderate,0.418405171,1,0.418,ns,T-test,Neutrophil CD36,score,HD,Moderate,0.373747684,1,0.37,ns,T-test,Neutrophil ALOX5AP,score,HD,Moderate,0.361073796,1,0.3611,ns,T-test,Neutrophil HLA-DPA1,score,HD,Moderate,0.323038413,0.97,0.323,ns,T-test,Neutrophil IRF8,score,HD,Moderate,0.320944316,0.96,0.32,ns,T-test,Neutrophil LYPD2,score,HD,Moderate,0.318025868,0.64,0.32,ns,T-test,Neutrophil CD74,score,HD,Moderate,0.317454238,0.95,0.32,ns,T-test,Neutrophil HLA-DQB1,score,HD,Moderate,0.250970611,0.75,0.25,ns,T-test,Neutrophil NKG7,score,HD,Moderate,0.233415544,0.7,0.233,ns,T-test,Neutrophil CSTA,score,HD,Moderate,0.232670104,0.7,0.233,ns,T-test,Neutrophil CCL3L1,score,HD,Moderate,0.207550448,0.62,0.21,ns,T-test,Neutrophil HMOX1,score,HD,Moderate,0.204086911,0.61,0.204,ns,T-test,Neutrophil ITM2C,score,HD,Moderate,0.203088634,0.61,0.203,ns,T-test,Neutrophil PTGDS,score,HD,Moderate,0.185676314,0.56,0.186,ns,T-test,Neutrophil IRF7,score,HD,Moderate,0.163823976,0.49,0.16,ns,T-test,Neutrophil PLD4,score,HD,Moderate,0.157797665,0.47,0.158,ns,T-test,Neutrophil FCER1A,score,HD,Moderate,0.157639838,0.32,0.16,ns,T-test,Neutrophil RHOC,score,HD,Moderate,0.154719759,0.46,0.15,ns,T-test,Neutrophil CCL5,score,HD,Moderate,0.138343194,0.42,0.138,ns,T-test,Neutrophil HLA-DQA1,score,HD,Moderate,0.121796489,0.37,0.12,ns,T-test,Neutrophil PROK2,score,HD,Moderate,0.1085119,0.33,0.11,ns,T-test,Neutrophil PPBP,score,HD,Moderate,0.105568578,0.32,0.1056,ns,T-test,Neutrophil VCAN,score,HD,Moderate,0.09465496,0.28,0.095,ns,T-test,Neutrophil GZMB,score,HD,Moderate,0.085032858,0.26,0.085,ns,T-test,Neutrophil TCF4,score,HD,Moderate,0.084278061,0.25,0.084,ns,T-test,Neutrophil FCGR3A,score,HD,Moderate,0.076478594,0.23,0.0765,ns,T-test,Neutrophil GNLY,score,HD,Moderate,0.075273172,0.23,0.075,ns,T-test,Neutrophil IFITM1,score,HD,Moderate,0.073261642,0.22,0.073,ns,T-test,Neutrophil MS4A7,score,HD,Moderate,0.071554242,0.21,0.072,ns,T-test,Neutrophil S100A9,score,HD,Moderate,0.048642983,0.15,0.049,*,T-test,Neutrophil PI3,score,HD,Moderate,0.04225871,0.13,0.0423,*,T-test,Neutrophil IGKC,score,HD,Moderate,0.021425678,0.064,0.021,*,T-test,Neutrophil IFITM3,score,HD,Moderate,0.013065401,0.039,0.013,*,T-test,Neutrophil IFITM2,score,HD,Moderate,0.010541842,0.032,0.011,*,T-test,Neutrophil SMIM25,score,HD,Moderate,0.008262388,0.025,0.00826,**,T-test,Neutrophil CXCR2,score,HD,Moderate,0.007804739,0.023,0.0078,**,T-test,Neutrophil LYZ,score,HD,Moderate,0.005054294,0.015,0.0051,**,T-test,Neutrophil MS4A6A,score,HD,Moderate,0.004667569,0.014,0.0047,**,T-test,Neutrophil S100A12,score,HD,Moderate,0.003458918,0.01,0.0035,**,T-test,Neutrophil JCHAIN,score,HD,Moderate,0.001606419,0.0048,0.0016,**,T-test,Neutrophil WARS,score,HD,Moderate,0.001288458,0.0039,0.0013,**,T-test,Neutrophil JUN,score,HD,Moderate,0.000987345,0.003,0.00099,***,T-test,Neutrophil IER3,score,HD,Moderate,0.000487558,0.0015,0.00049,***,T-test,Neutrophil S100A8,score,HD,Moderate,0.000449313,0.0013,0.00045,***,T-test,Neutrophil JUN,score,Moderate,Severe,9.24E-15,2.80E-14,9.20E-15,****,T-test,Plasmacytoid DC HLA-DPA1,score,Moderate,Severe,9.23E-09,2.80E-08,9.20E-09,****,T-test,Plasmacytoid DC ITM2C,score,Moderate,Severe,7.94E-07,2.40E-06,7.90E-07,****,T-test,Plasmacytoid DC GNLY,score,Moderate,Severe,6.76E-06,2.00E-05,6.80E-06,****,T-test,Plasmacytoid DC C12orf75,score,Moderate,Severe,6.48E-07,1.90E-06,6.50E-07,****,T-test,Plasmacytoid DC SERPINF1,score,Moderate,Severe,6.16E-06,1.80E-05,6.20E-06,****,T-test,Plasmacytoid DC NKG7,score,Moderate,Severe,5.66E-06,1.70E-05,5.70E-06,****,T-test,Plasmacytoid DC HLA-DRB1,score,Moderate,Severe,5.57E-09,1.70E-08,5.60E-09,****,T-test,Plasmacytoid DC IRF8,score,Moderate,Severe,3.00E-05,9.00E-05,3.00E-05,****,T-test,Plasmacytoid DC PLD4,score,Moderate,Severe,1.97E-06,5.90E-06,2.00E-06,****,T-test,Plasmacytoid DC HLA-DPB1,score,Moderate,Severe,1.86E-08,5.60E-08,1.90E-08,****,T-test,Plasmacytoid DC IGKC,score,Moderate,Severe,1.64E-09,4.90E-09,1.60E-09,****,T-test,Plasmacytoid DC TCF4,score,Moderate,Severe,1.41E-13,4.20E-13,1.40E-13,****,T-test,Plasmacytoid DC CCL5,score,Moderate,Severe,1.33E-06,4.00E-06,1.30E-06,****,T-test,Plasmacytoid DC CD14,score,Moderate,Severe,0.972302103,1,0.97,ns,T-test,Plasmacytoid DC HMOX1,score,Moderate,Severe,0.913264234,1,0.913,ns,T-test,Plasmacytoid DC RHOC,score,Moderate,Severe,0.909717263,1,0.91,ns,T-test,Plasmacytoid DC VCAN,score,Moderate,Severe,0.883791099,1,0.88,ns,T-test,Plasmacytoid DC CXCL8,score,Moderate,Severe,0.8698743,1,0.87,ns,T-test,Plasmacytoid DC MS4A6A,score,Moderate,Severe,0.81949067,1,0.819,ns,T-test,Plasmacytoid DC PPBP,score,Moderate,Severe,0.807793616,1,0.81,ns,T-test,Plasmacytoid DC IER3,score,Moderate,Severe,0.787693416,1,0.79,ns,T-test,Plasmacytoid DC GCA,score,Moderate,Severe,0.773046526,1,0.773,ns,T-test,Plasmacytoid DC CCL3,score,Moderate,Severe,0.764802796,1,0.76,ns,T-test,Plasmacytoid DC SOD2,score,Moderate,Severe,0.743502181,1,0.744,ns,T-test,Plasmacytoid DC GZMB,score,Moderate,Severe,0.727478772,1,0.72748,ns,T-test,Plasmacytoid DC IL1B,score,Moderate,Severe,0.689517798,1,0.69,ns,T-test,Plasmacytoid DC LYZ,score,Moderate,Severe,0.635107812,1,0.635,ns,T-test,Plasmacytoid DC CMTM2,score,Moderate,Severe,0.621006846,1,0.62,ns,T-test,Plasmacytoid DC MS4A7,score,Moderate,Severe,0.60426777,1,0.604,ns,T-test,Plasmacytoid DC SMIM25,score,Moderate,Severe,0.596677559,1,0.6,ns,T-test,Plasmacytoid DC SERPINA1,score,Moderate,Severe,0.587931504,1,0.59,ns,T-test,Plasmacytoid DC CSF1R,score,Moderate,Severe,0.568140987,1,0.57,ns,T-test,Plasmacytoid DC TCF7L2,score,Moderate,Severe,0.554871717,1,0.55,ns,T-test,Plasmacytoid DC CXCR2,score,Moderate,Severe,0.477472553,1,0.48,ns,T-test,Plasmacytoid DC S100A12,score,Moderate,Severe,0.455384845,1,0.46,ns,T-test,Plasmacytoid DC FCGR3B,score,Moderate,Severe,0.318127286,0.64,0.32,ns,T-test,Plasmacytoid DC LST1,score,Moderate,Severe,0.249082957,0.75,0.25,ns,T-test,Plasmacytoid DC CSTA,score,Moderate,Severe,0.2331995,0.7,0.23,ns,T-test,Plasmacytoid DC NAMPT,score,Moderate,Severe,0.189289042,0.57,0.19,ns,T-test,Plasmacytoid DC CLEC10A,score,Moderate,Severe,0.180925034,0.54,0.18,ns,T-test,Plasmacytoid DC AC020656.1,score,Moderate,Severe,0.131151418,0.39,0.13,ns,T-test,Plasmacytoid DC SLC25A37,score,Moderate,Severe,0.122504074,0.37,0.12,ns,T-test,Plasmacytoid DC PTGDS,score,Moderate,Severe,0.09863708,0.3,0.099,ns,T-test,Plasmacytoid DC FCER1A,score,Moderate,Severe,0.086416108,0.26,0.086,ns,T-test,Plasmacytoid DC IFITM3,score,Moderate,Severe,0.08020637,0.24,0.08,ns,T-test,Plasmacytoid DC S100A8,score,Moderate,Severe,0.070435944,0.21,0.07,ns,T-test,Plasmacytoid DC HLA-DRA,score,Moderate,Severe,0.058504446,0.18,0.0585,ns,T-test,Plasmacytoid DC CD36,score,Moderate,Severe,0.032548036,0.098,0.0325,*,T-test,Plasmacytoid DC G0S2,score,Moderate,Severe,0.027193598,0.082,0.027,*,T-test,Plasmacytoid DC LILRA4,score,Moderate,Severe,0.023494526,0.07,0.023,*,T-test,Plasmacytoid DC CCL3L1,score,Moderate,Severe,0.020824478,0.042,0.021,*,T-test,Plasmacytoid DC HLA-DQA1,score,Moderate,Severe,0.015436498,0.046,0.015,*,T-test,Plasmacytoid DC FCGR3A,score,Moderate,Severe,0.014424102,0.043,0.014,*,T-test,Plasmacytoid DC HLA-DQB1,score,Moderate,Severe,0.014249928,0.043,0.0142,*,T-test,Plasmacytoid DC S100A9,score,Moderate,Severe,0.008142787,0.024,0.0081,**,T-test,Plasmacytoid DC WARS,score,Moderate,Severe,0.007681096,0.023,0.00768,**,T-test,Plasmacytoid DC CD74,score,Moderate,Severe,0.002682454,0.008,0.0027,**,T-test,Plasmacytoid DC IFITM1,score,Moderate,Severe,0.001232607,0.0037,0.0012,**,T-test,Plasmacytoid DC JCHAIN,score,Moderate,Severe,0.000204001,0.00061,0.0002,***,T-test,Plasmacytoid DC ALOX5AP,score,Moderate,Severe,0.000195001,0.00059,0.0002,***,T-test,Plasmacytoid DC IRF7,score,Moderate,Severe,0.000194946,0.00058,0.00019,***,T-test,Plasmacytoid DC ALOX5AP,score,HD,Severe,9.94E-05,3.00E-04,9.90E-05,****,T-test,Plasmacytoid DC PPBP,score,HD,Severe,9.89E-06,3.00E-05,9.90E-06,****,T-test,Plasmacytoid DC GNLY,score,HD,Severe,7.69E-06,2.30E-05,7.70E-06,****,T-test,Plasmacytoid DC HLA-DRB1,score,HD,Severe,4.89E-09,1.50E-08,4.90E-09,****,T-test,Plasmacytoid DC GZMB,score,HD,Severe,2.06E-05,6.20E-05,2.10E-05,****,T-test,Plasmacytoid DC C12orf75,score,HD,Severe,1.39E-08,4.20E-08,1.40E-08,****,T-test,Plasmacytoid DC ITM2C,score,HD,Severe,1.38E-05,4.10E-05,1.40E-05,****,T-test,Plasmacytoid DC CCL3,score,HD,Severe,0.975646627,1,0.98,ns,T-test,Plasmacytoid DC CSF1R,score,HD,Severe,0.957981982,1,0.96,ns,T-test,Plasmacytoid DC HLA-DPA1,score,HD,Severe,0.828838592,1,0.82884,ns,T-test,Plasmacytoid DC CXCR2,score,HD,Severe,0.741377663,1,0.74,ns,T-test,Plasmacytoid DC FCGR3A,score,HD,Severe,0.683331672,1,0.683,ns,T-test,Plasmacytoid DC IFITM1,score,HD,Severe,0.667099437,1,0.6671,ns,T-test,Plasmacytoid DC LST1,score,HD,Severe,0.598124535,1,0.6,ns,T-test,Plasmacytoid DC S100A9,score,HD,Severe,0.592350957,1,0.5924,ns,T-test,Plasmacytoid DC SLC25A37,score,HD,Severe,0.521581073,1,0.52,ns,T-test,Plasmacytoid DC S100A12,score,HD,Severe,0.508927231,1,0.51,ns,T-test,Plasmacytoid DC CSTA,score,HD,Severe,0.481095188,1,0.48,ns,T-test,Plasmacytoid DC FCER1A,score,HD,Severe,0.469238957,1,0.469,ns,T-test,Plasmacytoid DC S100A8,score,HD,Severe,0.447003733,1,0.447,ns,T-test,Plasmacytoid DC CLEC10A,score,HD,Severe,0.446905277,1,0.45,ns,T-test,Plasmacytoid DC CXCL8,score,HD,Severe,0.434988659,1,0.43,ns,T-test,Plasmacytoid DC LILRA4,score,HD,Severe,0.366579487,1,0.367,ns,T-test,Plasmacytoid DC NAMPT,score,HD,Severe,0.334558445,1,0.33,ns,T-test,Plasmacytoid DC PROK2,score,HD,Severe,0.320288562,0.64,0.32,ns,T-test,Plasmacytoid DC CMTM2,score,HD,Severe,0.318127286,0.95,0.32,ns,T-test,Plasmacytoid DC FCGR3B,score,HD,Severe,0.318127286,0.64,0.32,ns,T-test,Plasmacytoid DC VCAN,score,HD,Severe,0.311937355,0.94,0.31,ns,T-test,Plasmacytoid DC AC020656.1,score,HD,Severe,0.28035714,0.84,0.28,ns,T-test,Plasmacytoid DC SERPINA1,score,HD,Severe,0.265802484,0.8,0.27,ns,T-test,Plasmacytoid DC TCF4,score,HD,Severe,0.23802935,0.71,0.24,ns,T-test,Plasmacytoid DC IRF8,score,HD,Severe,0.234766124,0.7,0.235,ns,T-test,Plasmacytoid DC G0S2,score,HD,Severe,0.234163424,0.7,0.234,ns,T-test,Plasmacytoid DC TCF7L2,score,HD,Severe,0.215489222,0.65,0.22,ns,T-test,Plasmacytoid DC NKG7,score,HD,Severe,0.200940841,0.6,0.201,ns,T-test,Plasmacytoid DC PTGDS,score,HD,Severe,0.181402413,0.54,0.181,ns,T-test,Plasmacytoid DC SMIM25,score,HD,Severe,0.16705214,0.5,0.17,ns,T-test,Plasmacytoid DC HLA-DQB1,score,HD,Severe,0.14891687,0.45,0.1489,ns,T-test,Plasmacytoid DC RHOC,score,HD,Severe,0.146485227,0.44,0.15,ns,T-test,Plasmacytoid DC IER3,score,HD,Severe,0.136464233,0.41,0.14,ns,T-test,Plasmacytoid DC IL1B,score,HD,Severe,0.135915908,0.41,0.14,ns,T-test,Plasmacytoid DC CD14,score,HD,Severe,0.112160529,0.34,0.11,ns,T-test,Plasmacytoid DC IFITM3,score,HD,Severe,0.107370867,0.32,0.11,ns,T-test,Plasmacytoid DC JUN,score,HD,Severe,0.102551176,0.31,0.10255,ns,T-test,Plasmacytoid DC JCHAIN,score,HD,Severe,0.102507211,0.31,0.1025,ns,T-test,Plasmacytoid DC WARS,score,HD,Severe,0.097499134,0.29,0.0975,ns,T-test,Plasmacytoid DC LYZ,score,HD,Severe,0.095124996,0.29,0.095,ns,T-test,Plasmacytoid DC SOD2,score,HD,Severe,0.082091967,0.25,0.082,ns,T-test,Plasmacytoid DC MS4A7,score,HD,Severe,0.073562398,0.22,0.074,ns,T-test,Plasmacytoid DC MS4A6A,score,HD,Severe,0.073130572,0.22,0.073,ns,T-test,Plasmacytoid DC HLA-DQA1,score,HD,Severe,0.064182135,0.19,0.064,ns,T-test,Plasmacytoid DC CD74,score,HD,Severe,0.049917257,0.15,0.0499,*,T-test,Plasmacytoid DC HMOX1,score,HD,Severe,0.037654735,0.11,0.038,*,T-test,Plasmacytoid DC CCL3L1,score,HD,Severe,0.020824478,0.042,0.021,*,T-test,Plasmacytoid DC GCA,score,HD,Severe,0.015152901,0.045,0.015,*,T-test,Plasmacytoid DC CCL5,score,HD,Severe,0.013359311,0.04,0.013,*,T-test,Plasmacytoid DC PLD4,score,HD,Severe,0.002163354,0.0065,0.0022,**,T-test,Plasmacytoid DC CD36,score,HD,Severe,0.00213979,0.0064,0.0021,**,T-test,Plasmacytoid DC HLA-DRA,score,HD,Severe,0.001404229,0.0042,0.0014,**,T-test,Plasmacytoid DC HLA-DPB1,score,HD,Severe,0.001200188,0.0036,0.0012,**,T-test,Plasmacytoid DC IGKC,score,HD,Severe,0.000653003,0.002,0.00065,***,T-test,Plasmacytoid DC IRF7,score,HD,Severe,0.000473992,0.0014,0.00047,***,T-test,Plasmacytoid DC SERPINF1,score,HD,Severe,0.000136337,0.00041,0.00014,***,T-test,Plasmacytoid DC TCF4,score,HD,Moderate,5.17E-05,0.00016,5.20E-05,****,T-test,Plasmacytoid DC PPBP,score,HD,Moderate,3.65E-05,0.00011,3.70E-05,****,T-test,Plasmacytoid DC IFITM3,score,HD,Moderate,0.993894404,1,0.99,ns,T-test,Plasmacytoid DC S100A12,score,HD,Moderate,0.970029106,1,0.97,ns,T-test,Plasmacytoid DC PTGDS,score,HD,Moderate,0.959342034,1,0.959,ns,T-test,Plasmacytoid DC CD74,score,HD,Moderate,0.957854107,1,0.9579,ns,T-test,Plasmacytoid DC SERPINF1,score,HD,Moderate,0.869165622,1,0.86917,ns,T-test,Plasmacytoid DC GNLY,score,HD,Moderate,0.867205735,1,0.87,ns,T-test,Plasmacytoid DC HLA-DQA1,score,HD,Moderate,0.866658661,1,0.867,ns,T-test,Plasmacytoid DC CSTA,score,HD,Moderate,0.858500351,1,0.86,ns,T-test,Plasmacytoid DC NAMPT,score,HD,Moderate,0.852813961,1,0.85,ns,T-test,Plasmacytoid DC ITM2C,score,HD,Moderate,0.790782709,1,0.79,ns,T-test,Plasmacytoid DC CCL3,score,HD,Moderate,0.78794666,1,0.79,ns,T-test,Plasmacytoid DC CLEC10A,score,HD,Moderate,0.702330872,1,0.7,ns,T-test,Plasmacytoid DC CSF1R,score,HD,Moderate,0.697020173,1,0.7,ns,T-test,Plasmacytoid DC LST1,score,HD,Moderate,0.647586234,1,0.65,ns,T-test,Plasmacytoid DC PLD4,score,HD,Moderate,0.636448455,1,0.6364,ns,T-test,Plasmacytoid DC SLC25A37,score,HD,Moderate,0.602536525,1,0.6,ns,T-test,Plasmacytoid DC IRF7,score,HD,Moderate,0.593223077,1,0.59322,ns,T-test,Plasmacytoid DC TCF7L2,score,HD,Moderate,0.54302744,1,0.54,ns,T-test,Plasmacytoid DC FCER1A,score,HD,Moderate,0.524317054,1,0.524,ns,T-test,Plasmacytoid DC CXCL8,score,HD,Moderate,0.493536576,1,0.49,ns,T-test,Plasmacytoid DC SERPINA1,score,HD,Moderate,0.469734722,1,0.47,ns,T-test,Plasmacytoid DC LILRA4,score,HD,Moderate,0.413272955,1,0.413,ns,T-test,Plasmacytoid DC ALOX5AP,score,HD,Moderate,0.409734845,1,0.4097,ns,T-test,Plasmacytoid DC VCAN,score,HD,Moderate,0.39661354,1,0.4,ns,T-test,Plasmacytoid DC IGKC,score,HD,Moderate,0.385324178,1,0.38532,ns,T-test,Plasmacytoid DC CXCR2,score,HD,Moderate,0.372361879,1,0.37,ns,T-test,Plasmacytoid DC IL1B,score,HD,Moderate,0.358006025,1,0.36,ns,T-test,Plasmacytoid DC PROK2,score,HD,Moderate,0.320288562,0.64,0.32,ns,T-test,Plasmacytoid DC SMIM25,score,HD,Moderate,0.319306129,0.96,0.32,ns,T-test,Plasmacytoid DC CMTM2,score,HD,Moderate,0.319306129,0.96,0.32,ns,T-test,Plasmacytoid DC JCHAIN,score,HD,Moderate,0.266425402,0.8,0.2664,ns,T-test,Plasmacytoid DC HLA-DRB1,score,HD,Moderate,0.243296987,0.73,0.24,ns,T-test,Plasmacytoid DC FCGR3A,score,HD,Moderate,0.203582792,0.61,0.204,ns,T-test,Plasmacytoid DC RHOC,score,HD,Moderate,0.200100851,0.6,0.2,ns,T-test,Plasmacytoid DC IER3,score,HD,Moderate,0.197353219,0.59,0.2,ns,T-test,Plasmacytoid DC CD36,score,HD,Moderate,0.196404275,0.59,0.1964,ns,T-test,Plasmacytoid DC CCL5,score,HD,Moderate,0.187716061,0.56,0.188,ns,T-test,Plasmacytoid DC HMOX1,score,HD,Moderate,0.171861297,0.52,0.172,ns,T-test,Plasmacytoid DC HLA-DPB1,score,HD,Moderate,0.166767065,0.5,0.1668,ns,T-test,Plasmacytoid DC CD14,score,HD,Moderate,0.123308173,0.37,0.12,ns,T-test,Plasmacytoid DC C12orf75,score,HD,Moderate,0.110181404,0.33,0.11,ns,T-test,Plasmacytoid DC HLA-DRA,score,HD,Moderate,0.108929454,0.33,0.1089,ns,T-test,Plasmacytoid DC IFITM1,score,HD,Moderate,0.073122401,0.22,0.0731,ns,T-test,Plasmacytoid DC MS4A6A,score,HD,Moderate,0.073050213,0.22,0.073,ns,T-test,Plasmacytoid DC LYZ,score,HD,Moderate,0.064159307,0.19,0.064,ns,T-test,Plasmacytoid DC SOD2,score,HD,Moderate,0.063716419,0.19,0.064,ns,T-test,Plasmacytoid DC S100A8,score,HD,Moderate,0.061811055,0.19,0.062,ns,T-test,Plasmacytoid DC IRF8,score,HD,Moderate,0.058854905,0.18,0.059,ns,T-test,Plasmacytoid DC NKG7,score,HD,Moderate,0.048229561,0.14,0.048,*,T-test,Plasmacytoid DC MS4A7,score,HD,Moderate,0.046698638,0.14,0.047,*,T-test,Plasmacytoid DC AC020656.1,score,HD,Moderate,0.040026524,0.12,0.04,*,T-test,Plasmacytoid DC GCA,score,HD,Moderate,0.038684837,0.12,0.039,*,T-test,Plasmacytoid DC G0S2,score,HD,Moderate,0.038297108,0.11,0.038,*,T-test,Plasmacytoid DC S100A9,score,HD,Moderate,0.026007407,0.078,0.026,*,T-test,Plasmacytoid DC HLA-DQB1,score,HD,Moderate,0.001606623,0.0048,0.0016,**,T-test,Plasmacytoid DC GZMB,score,HD,Moderate,0.000615864,0.0018,0.00062,***,T-test,Plasmacytoid DC WARS,score,HD,Moderate,0.00028915,0.00087,0.00029,***,T-test,Plasmacytoid DC JUN,score,HD,Moderate,0.000253285,0.00076,0.00025,***,T-test,Plasmacytoid DC HLA-DPA1,score,HD,Moderate,0.000181008,0.00054,0.00018,***,T-test,Plasmacytoid DC