Gene,Annotation,Cramer’s V,Prevalence in Pharyngitis Isolates,Prevalence in Invasive Isolates,LMM P-Value
group_2809,hypothetical protein,0.88,0.16,0.06,0.0002
group_1823,hypothetical protein,0.78,0.19,0.03,0.0002
group_2963,Integrase,0.77,0.18,0.02,0.0003
group_2533,YcfA-like protein,0.81,0.34,0.07,0.0005
group_3462,hypothetical protein,0.83,0.04,0.07,0.0009
group_3496,hypothetical protein,0.83,0.04,0.07,0.0009
group_351,hypothetical protein,0.94,0.44,0.56,0.0011
group_145,hypothetical protein,0.90,0.43,0.14,0.0011
group_2806,hypothetical protein,0.89,0.18,0.17,0.0011
xerS_2,site-specific tyrosine recombinase XerC,0.90,0.12,0.34,0.0012
group_789,hypothetical protein,0.87,0.18,0.07,0.0012
group_3488,DNA-binding transcriptional repressor AcrR,0.92,0.04,0.04,0.0015
group_3489,Putative multidrug export ATP-binding/permease protein,0.92,0.04,0.04,0.0015
group_3490,Putative multidrug export ATP-binding/permease protein,0.92,0.04,0.04,0.0015
mepA,Multidrug export protein MepA,0.92,0.04,0.04,0.0015
group_1751,hypothetical protein,0.88,0.17,0.07,0.0015
group_2952,hypothetical protein,0.95,0.09,0.08,0.0015
group_2953,hypothetical protein,0.95,0.09,0.08,0.0015
group_1257,hypothetical protein,0.85,0.05,0.07,0.0015
group_3464,hypothetical protein,0.85,0.05,0.07,0.0015
group_2532,hypothetical protein,0.82,0.34,0.07,0.0018
group_2974,hypothetical protein,0.77,0.18,0.03,0.0019
group_2808,hypothetical protein,0.91,0.31,0.43,0.0022
group_264,hypothetical protein,0.91,0.32,0.53,0.0024
group_821,Helix-destabilizing protein,0.81,0.40,0.16,0.0025
group_2946,hypothetical protein,0.96,0.29,0.14,0.0025
group_817,hypothetical protein,0.92,0.42,0.50,0.0029
group_1119,putative P-loop ATPase,0.90,0.18,0.17,0.0037
group_2807,hypothetical protein,0.90,0.18,0.17,0.0037
group_1901,hypothetical protein,0.84,0.31,0.03,0.0042
group_2527,hypothetical protein,0.93,0.18,0.12,0.0043
group_2528,hypothetical protein,0.93,0.18,0.12,0.0043
group_474,hypothetical protein,0.85,0.14,0.06,0.0044
group_353,hypothetical protein,0.94,0.29,0.50,0.0052
group_1805,hypothetical protein,0.91,0.10,0.08,0.0053
group_2943,hypothetical protein,0.91,0.10,0.08,0.0053
group_2949,hypothetical protein,0.91,0.10,0.08,0.0053
group_2950,hypothetical protein,0.91,0.10,0.08,0.0053
speA,Scarlet fever toxin,0.91,0.10,0.08,0.0053
group_2966,hypothetical protein,0.81,0.30,0.31,0.0061
group_2967,hypothetical protein,0.81,0.30,0.31,0.0061
group_379,LexA repressor,0.95,0.26,0.15,0.0061
group_3585,hypothetical protein,0.88,0.02,0.06,0.0071
group_1903,hypothetical protein,0.96,0.04,0.08,0.0071
group_3265,hypothetical protein,0.96,0.04,0.08,0.0071
group_1750,hypothetical protein,0.85,0.18,0.30,0.0080
group_3268,hypothetical protein,0.94,0.07,0.06,0.0080
group_2970,hypothetical protein,0.75,0.24,0.04,0.0082
group_2965,Phage anti-repressor protein,0.81,0.29,0.35,0.0083
group_2515,hypothetical protein,0.92,0.19,0.16,0.0083
group_1168,"phage major tail protein, TP901-1 family",0.94,0.31,0.14,0.0091
group_1169,hypothetical protein,0.94,0.31,0.14,0.0091
group_1806,hypothetical protein,0.94,0.31,0.14,0.0091
group_1807,hypothetical protein,0.94,0.31,0.14,0.0091
group_1808,baseplate wedge subunit and tail pin,0.94,0.31,0.14,0.0091
group_1809,hypothetical protein,0.94,0.31,0.14,0.0091
group_1810,hypothetical protein,0.94,0.31,0.14,0.0091
group_1811,HeH/LEM domain protein,0.94,0.31,0.14,0.0091
group_1930,hypothetical protein,0.94,0.31,0.14,0.0091
group_1931,Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase,0.94,0.31,0.14,0.0091
group_2942,hypothetical protein,0.94,0.31,0.14,0.0091
group_2944,CHAP domain protein,0.94,0.31,0.14,0.0091
group_2945,"phage holin, LL-H family",0.94,0.31,0.14,0.0091
group_2947,hypothetical protein,0.94,0.31,0.14,0.0091
group_2948,hypothetical protein,0.94,0.31,0.14,0.0091
group_2951,Phage gp6-like head-tail connector protein,0.94,0.31,0.14,0.0091
group_460,Phage-related protein,0.94,0.31,0.14,0.0091
group_824,hypothetical protein,0.94,0.31,0.14,0.0091
gltC,Cys regulon transcriptional activator,0.80,0.99,0.93,0.0094
dnaD_1,DNA replication protein DnaD,0.78,0.26,0.05,0.0101
ennX_2,Virulence factor-related M protein precursor,0.96,0.58,0.84,0.0101
ermA1,rRNA adenine N-6-methyltransferase,0.44,0.00,0.07,0.0110
group_3470,thiamine kinase,0.44,0.00,0.07,0.0110
group_1170,"phage portal protein, SPP1 family",0.86,0.19,0.11,0.0114
group_1812,"phage head morphogenesis protein, SPP1 gp7 family",0.86,0.19,0.11,0.0114
group_2954,hypothetical protein,0.86,0.19,0.11,0.0114
group_2968,hypothetical protein,0.74,0.21,0.04,0.0114
group_825,hypothetical protein,0.86,0.19,0.11,0.0114
group_3597,hypothetical protein,0.71,0.02,0.06,0.0119
group_3598,hypothetical protein,0.71,0.02,0.06,0.0119
group_2971,hypothetical protein,0.75,0.24,0.04,0.0121
group_1178,hypothetical protein,0.95,0.38,0.23,0.0122
group_2831,"gram-positive signal peptide, YSIRK family",0.93,0.09,0.03,0.0128
group_2969,hypothetical protein,0.72,0.18,0.03,0.0132
group_2530,hypothetical protein,0.78,0.53,0.14,0.0136
group_2516,hypothetical protein,0.92,0.27,0.17,0.0145
group_2678,hypothetical protein,0.96,0.09,0.04,0.0149
group_650,hypothetical protein,0.88,0.33,0.09,0.0149
group_1752,putative phage-encoded protein,0.93,0.28,0.33,0.0151
group_3394,hypothetical protein,0.78,0.05,0.11,0.0156
group_2811,helix-turn-helix protein,0.93,0.19,0.32,0.0162
group_3823,hypothetical protein,0.98,0.06,0.02,0.0162
tetM,Tetracycline resistance protein TetM from transposon TnFO1,0.85,0.04,0.23,0.0164
group_3459,ATP-dependent Clp protease proteolytic subunit 1,0.46,0.03,0.03,0.0176
group_1175,streptodornase,0.80,0.36,0.31,0.0179
group_822,hypothetical protein,0.76,0.35,0.17,0.0181
group_880,hypothetical protein,0.57,0.03,0.02,0.0185
group_1118,hypothetical protein,0.93,0.28,0.50,0.0188
group_1120,hypothetical protein,0.94,0.27,0.33,0.0192
group_2541,hypothetical protein,0.81,0.39,0.40,0.0197
group_2935,Siphovirus Gp157,0.75,0.37,0.17,0.0197
group_638,hypothetical protein,0.81,0.39,0.40,0.0197
group_1171,"phage terminase, large subunit, PBSX family",0.86,0.19,0.11,0.0203
group_3158,hypothetical protein,0.98,0.08,0.11,0.0203
group_1248,hypothetical protein,0.79,0.05,0.11,0.0212
repB,Replication protein RepB,0.79,0.05,0.11,0.0212
group_1781,hypothetical protein,0.97,0.51,0.79,0.0214
group_2810,"Ribbon-helix-helix protein, copG family",0.88,0.17,0.07,0.0216
group_4931,hypothetical protein,0.50,0.01,0.02,0.0219
group_1820,hypothetical protein,0.82,0.30,0.35,0.0227
group_2964,Helix-turn-helix domain protein,0.82,0.30,0.35,0.0227
group_1214,"phage protein, HK97 gp10 family",0.87,0.12,0.05,0.0236
group_2787,hypothetical protein,0.92,0.16,0.07,0.0239
group_1862,hypothetical protein,0.96,0.01,0.26,0.0246
group_1916,hypothetical protein,0.96,0.00,0.04,0.0251
group_3695,hypothetical protein,0.69,0.02,0.03,0.0269
group_1422,hypothetical protein,0.91,0.36,0.25,0.0276
group_1167,Holliday junction resolvase,0.80,0.42,0.18,0.0283
group_3404,hypothetical protein,0.85,0.26,0.03,0.0303
group_1204,Exo-glucosaminidase LytG precursor,0.98,0.01,0.26,0.0318
group_2534,Terminase small subunit,0.95,0.17,0.05,0.0329
group_2828,Fibronectin binding repeat,0.96,0.09,0.04,0.0340
group_3188,hypothetical protein,0.84,0.15,0.08,0.0346
group_2537,hypothetical protein,0.91,0.10,0.04,0.0348
group_2539,"phage major tail protein, TP901-1 family",0.91,0.10,0.04,0.0348
group_1261,hypothetical protein,0.79,0.06,0.07,0.0352
group_3477,hypothetical protein,0.79,0.06,0.07,0.0352
group_632,hypothetical protein,0.79,0.06,0.07,0.0352
group_870,hypothetical protein,0.79,0.06,0.07,0.0352
group_883,DNA topoisomerase 3,0.79,0.06,0.07,0.0352
group_2907,PD-(D/E)XK nuclease superfamily protein,0.89,0.22,0.15,0.0367
group_2908,hypothetical protein,0.89,0.22,0.15,0.0367
aphA_1,Aminoglycoside 3'-phosphotransferase,0.84,0.00,0.18,0.0371
group_3276,TDP-fucosamine acetyltransferase,0.82,0.00,0.17,0.0371
group_2939,hypothetical protein,0.91,0.12,0.14,0.0372
ecfA1_2,Energy-coupling factor transporter ATP-binding protein EcfA1,0.69,0.02,0.02,0.0383
group_1910,Multidrug export protein MepA,0.69,0.02,0.02,0.0383
group_1912,hypothetical protein,0.69,0.02,0.02,0.0383
group_3304,"ABC-type cobalt transport system, permease component CbiQ",0.69,0.02,0.02,0.0383
group_1952,hypothetical protein,0.79,0.06,0.08,0.0414
group_906,hypothetical protein,0.95,0.11,0.29,0.0415
group_1152,hypothetical protein,0.89,0.23,0.16,0.0417
group_1783,Helix-turn-helix domain protein,0.89,0.23,0.16,0.0417
group_1784,Polo kinase kinase,0.89,0.23,0.16,0.0417
group_2903,Integrase,0.88,0.22,0.16,0.0417
group_2904,hypothetical protein,0.88,0.22,0.16,0.0417
group_2905,hypothetical protein,0.88,0.22,0.16,0.0417
group_603,Beta antigen,0.95,0.10,0.11,0.0425
group_176,hypothetical protein,0.92,0.32,0.50,0.0434
ftsK_2,hypothetical protein,0.84,0.04,0.23,0.0438
group_907,hypothetical protein,0.81,0.72,0.70,0.0438
group_3460,hypothetical protein,0.69,0.03,0.03,0.0448
group_1412,hypothetical protein,0.94,0.26,0.15,0.0460
group_1785,hypothetical protein,0.89,0.24,0.20,0.0464
group_1174,Small integral membrane protein,0.82,0.54,0.37,0.0465
Int-Tn_1,Integrase,0.82,0.23,0.06,0.0482
group_812,hypothetical protein,0.74,0.27,0.17,0.0484
group_2972,hypothetical protein,0.75,0.29,0.06,0.0486
group_1192,hypothetical protein,0.89,0.35,0.50,0.0493
group_329,"Phage terminase-like protein, large subunit",0.85,0.73,0.92,0.0499