species compartment IC_Xinitialized Annotation_ENSEMBL Annotation_HGNC Ribosome Cytoplasm 1.90E+03 GO:0005840 GO:0005840 p53inac Nucleus 2.97E+02 ENSG00000141510 TP53 p53ac Nucleus 6.25E+00 ENSG00000141510 TP53 MDM2 Nucleus 2.06E+02 ENSG00000135679 MDM2 Wip1 Nucleus 2.23E+00 ENSG00000170836 PPM1D ATMP Nucleus 0.00E+00 ENSG00000149311 ATM ATRac Nucleus 0.00E+00 ENSG00000175054 ATR MDM2product1 Nucleus 6.25E+00 MDM2product2 Nucleus 6.25E+00 MDM2product3 Nucleus 6.25E+00 MDM2product4 Nucleus 6.25E+00 MDM2product5 Nucleus 6.25E+00 MDM2product6 Nucleus 6.25E+00 MDM2product7 Nucleus 6.25E+00 MDM2product8 Nucleus 6.25E+00 MDM2product9 Nucleus 6.25E+00 MDM2pro Nucleus 6.25E+00 Wip1product1 Nucleus 6.25E+00 Wip1product2 Nucleus 6.25E+00 Wip1product3 Nucleus 6.25E+00 Wip1product4 Nucleus 6.25E+00 Wip1product5 Nucleus 6.25E+00 Wip1product6 Nucleus 6.25E+00 Wip1product7 Nucleus 6.25E+00 Wip1product8 Nucleus 6.25E+00 Wip1product9 Nucleus 6.25E+00 Wip1pro Nucleus 6.25E+00 BRCA2 Nucleus 8.22E-01 ENSG00000139618 BRCA2 MSH6 Nucleus 4.55E+01 ENSG00000116062 MSH6 MGMT Nucleus 1.20E+02 ENSG00000170430 MGMT damageDSB Nucleus 2.43E-04 damageSSB Nucleus 6.03E-06 ppAKT_MDM2 Nucleus 0.00E+00 ENSG00000142208 ENSG00000105221 ENSG00000135679 AKT1 AKT2 MDM2 pMDM2 Nucleus 0.00E+00 ENSG00000135679 MDM2 ARF Nucleus 0.00E+00 ENSG00000147889 CDKN2A MDM4 Nucleus 2.72E-02 ENSG00000198625 MDM4 p53ac_MDM4 Nucleus 0.00E+00 ENSG00000141510 ENSG00000198625 TP53 MDM4 ATMinac Nucleus 1.50E+00 ENSG00000149311 ATM ATRinac Nucleus 2.40E+00 ENSG00000175054 ATR pRB Nucleus 8.00E+03 ENSG00000139687 RB1 pRBp Nucleus 5.36E-01 ENSG00000139687 RB1 pRBpp Nucleus 6.97E-03 ENSG00000139687 RB1 E2F Nucleus 1.12E+03 ENSG00000101412 ENSG00000007968 ENSG00000112242 E2F1 E2F2 E2F3 Cd Nucleus 2.33E-01 ENSG00000110092 ENSG00000118971 ENSG00000112576 CCND1 CCND2 CCND3 Mdi Nucleus 5.89E-01 ENSG00000110092 ENSG00000118971 ENSG00000112576 ENSG00000135446 ENSG00000105810 CCND1 CCND2 CCND3 CDK4 CDK6 Md Nucleus 3.85E+00 ENSG00000110092 ENSG00000118971 ENSG00000112576 ENSG00000135446 ENSG00000105810 CCND1 CCND2 CCND3 CDK4 CDK6 Mdp27 Nucleus 7.88E-01 ENSG00000110092 ENSG00000118971 ENSG00000112576 ENSG00000135446 ENSG00000105810 ENSG00000111276 CCND1 CCND2 CCND3 CDK4 CDK6 CDKN1B Ce Nucleus 2.55E-01 ENSG00000105173 ENSG00000175305 CCNE1 CCNE2 Mei Nucleus 8.89E-01 ENSG00000105173 ENSG00000175305 ENSG00000123374 CCNE1 CCNE2 CDK2 Me Nucleus 2.75E+00 ENSG00000105173 ENSG00000175305 ENSG00000123374 CCNE1 CCNE2 CDK2 Skp2 Nucleus 1.14E+01 ENSG00000145604 SKP2 Mep27 Nucleus 1.12E+00 ENSG00000105173 ENSG00000175305 ENSG00000123374 ENSG00000111276 CCNE1 CCNE2 CDK2 CDKN1B Pe Nucleus 1.41E+02 ENSG00000164045 CDC25A Pai Nucleus 4.92E+01 ENSG00000101224 CDC25B Pei Nucleus 1.60E+01 ENSG00000164045 CDC25A Pbi Nucleus 5.53E+01 ENSG00000158402 CDC25C Ca Nucleus 4.03E+00 ENSG00000145386 CCNA2 Mai Nucleus 1.40E+01 ENSG00000145386 ENSG00000123374 CCNA2 CDK2 Ma Nucleus 5.23E+00 ENSG00000145386 ENSG00000123374 CCNA2 CDK2 Map27 Nucleus 1.28E+00 ENSG00000145386 ENSG00000123374 ENSG00000111276 ENSG00000111276 CCNA2 CDK2 CDKN1B p27 Nucleus 2.04E+01 ENSG00000111276 CDKN1B Cdh1i Nucleus 5.98E-01 ENSG00000039068 CDH1 Cdh1a Nucleus 1.09E+02 ENSG00000039068 CDH1 E2Fp Nucleus 1.16E+01 ENSG00000101412 ENSG00000007968 ENSG00000112242 E2F1 E2F2 E2F3 p27p Nucleus 4.20E+00 ENSG00000111276 CDKN1B Pa Nucleus 4.16E+01 ENSG00000101224 CDC25B Cb Nucleus 3.44E+00 ENSG00000134057 CCNB1 Mbi Nucleus 3.90E+00 ENSG00000134057 ENSG00000170312 CCNB1 CDK1 Mb Nucleus 6.84E-01 ENSG00000134057 ENSG00000170312 CCNB1 CDK1 Cdc20i Nucleus 7.12E+01 ENSG00000117399 CDC20 Cdc20a Nucleus 7.30E-01 ENSG00000117399 CDC20 Pb Nucleus 9.40E+00 ENSG00000158402 CDC25C Wee1 Nucleus 2.65E+01 ENSG00000166483 WEE1 Wee1p Nucleus 1.67E+01 ENSG00000166483 WEE1 Mbp27 Nucleus 8.39E-02 ENSG00000134057 ENSG00000170312 ENSG00000111276 CCNB1 CDK1 CDKN1B Chk1 Nucleus 1.50E-01 ENSG00000149554 CHEK1 pRBc1 Nucleus 8.95E+03 ENSG00000139687 ENSG00000101412 ENSG00000007968 ENSG00000112242 RB1 E2F1 E2F2 E2F3 pRBc2 Nucleus 3.00E-01 ENSG00000139687 ENSG00000101412 ENSG00000007968 ENSG00000112242 RB1 E2F1 E2F2 E2F3 p21 Nucleus 2.09E+01 ENSG00000124762 CDKN1A Mdp21 Nucleus 4.83E-01 ENSG00000110092 ENSG00000118971 ENSG00000112576 ENSG00000135446 ENSG00000124762 CCND1 CCND2 CCND3 CDK4 CDK6 CDKN1A Mep21 Nucleus 2.29E-01 ENSG00000105173 ENSG00000175305 ENSG00000123374 ENSG00000124762 CCNE1 CCNE2 CDK2 CDKN1A Map21 Nucleus 2.62E-01 ENSG00000145386 ENSG00000123374 ENSG00000124762 CCNA2 CDK2 CDKN1A Mbp21 Nucleus 1.71E-02 ENSG00000134057 ENSG00000170312 ENSG00000124762 CCNB1 CDK1 CDKN1A L Extracellular 2.21E-17 ENSG00000121858 TNFSF10 R Cytoplasm 8.03E+00 ENSG00000104689 ENSG00000120889 TNFRSF10A TNFRSF10B L_R Cytoplasm 2.24E-16 ENSG00000121858 ENSG00000104689 ENSG00000120889 TNFSF10 TNFRSF10A TNFRSF10B Ractive Cytoplasm 7.56E-20 ENSG00000104689 ENSG00000120889 TNFRSF10A TNFRSF10B flip Cytoplasm 5.26E-01 ENSG00000003402 CFLAR Ractive_flip Cytoplasm 1.05E-19 ENSG00000104689 ENSG00000120889 ENSG00000003402 TNFRSF10A TNFRSF10B CFLAR pC8 Cytoplasm 2.65E+01 ENSG00000064012 ENSG00000003400 CASP8 CASP10 Ractive_pC8 Cytoplasm 6.34E-21 ENSG00000104689 ENSG00000120889 ENSG00000064012 ENSG00000003400 TNFRSF10A TNFRSF10B CASP8 CASP10 C8 Cytoplasm 3.67E-04 ENSG00000064012 ENSG00000003400 CASP8 CASP10 Bar Cytoplasm 8.42E-01 ENSG00000103429 BFAR C8_Bar Cytoplasm 9.51E-04 ENSG00000103429 ENSG00000064012 ENSG00000003400 BFAR CASP8 CASP10 pC3 Cytoplasm 8.08E+01 ENSG00000164305 ENSG00000165806 CASP3 CASP7 C8_pC3 Cytoplasm 4.69E-03 ENSG00000064012 ENSG00000003400 ENSG00000164305 ENSG00000165806 CASP8 CASP10 CASP3 CASP7 C3 Cytoplasm 1.37E-04 ENSG00000164305 ENSG00000165806 CASP3 CASP7 pC6 Cytoplasm 4.77E+01 ENSG00000138794 CASP6 C3_pC6 Cytoplasm 2.07E-08 ENSG00000164305 ENSG00000165806 ENSG00000138794 CASP3 CASP7 CASP6 C6 Cytoplasm 3.88E-04 ENSG00000138794 CASP6 C6_C8 Cytoplasm 9.77E-08 ENSG00000138794 ENSG00000064012 ENSG00000003400 CASP6 CASP8 CASP10 XIAP Cytoplasm 5.48E+00 ENSG00000101966 XIAP C3_XIAP Cytoplasm 4.70E-05 ENSG00000164305 ENSG00000165806 ENSG00000101966 CASP3 CASP7 XIAP PARP Cytoplasm 6.40E+02 ENSG00000143799 PARP1 C3_PARP Cytoplasm 2.75E-06 ENSG00000164305 ENSG00000165806 ENSG00000143799 CASP3 CASP7 PARP1 cPARP Cytoplasm 1.10E+00 ENSG00000143799 PARP1 Bid Cytoplasm 5.05E+01 ENSG00000015475 BID C8_Bid Cytoplasm 5.32E-05 ENSG00000064012 ENSG00000003400 ENSG00000015475 CASP8 CASP10 BID tBid Cytoplasm 1.16E-06 ENSG00000015475 BID Bcl2c Cytoplasm 1.25E+01 ENSG00000171791 ENSG00000171552 ENSG00000143384 BCL2 BCL2L1 MCL1 tBid_Bcl2c Cytoplasm 4.09E-05 ENSG00000015475 ENSG00000171791 ENSG00000171552 ENSG00000143384 BID BCL2 BCL2L1 MCL1 Bax Cytoplasm 8.83E+01 ENSG00000087088 BAX tBid_Bax Cytoplasm 3.24E-08 ENSG00000015475 ENSG00000087088 BID BAX Baxactive Cytoplasm 5.75E-05 ENSG00000087088 BAX Baxm Mitochondrion 7.72E-04 ENSG00000087088 BAX Bcl2 Mitochondrion 1.78E+00 ENSG00000171791 ENSG00000171552 ENSG00000143384 BCL2 BCL2L1 MCL1 Baxm_Bcl2 Mitochondrion 3.88E-03 ENSG00000087088 ENSG00000171791 ENSG00000171552 ENSG00000143384 BAX BCL2 BCL2L1 MCL1 Bax2 Mitochondrion 1.88E-05 ENSG00000087088 BAX Bax2_Bcl2 Mitochondrion 9.47E-05 ENSG00000087088 ENSG00000171791 ENSG00000171552 ENSG00000143384 BAX BCL2 BCL2L1 MCL1 Bax4 Mitochondrion 1.12E-08 ENSG00000087088 BAX Bax4_Bcl2 Mitochondrion 5.65E-08 ENSG00000087088 ENSG00000171791 ENSG00000171552 ENSG00000143384 BAX BCL2 BCL2L1 MCL1 M Mitochondrion 2.26E+03 GO:0005739 Bax4_M Mitochondrion 8.02E-08 ENSG00000087088 BAX Mactive Mitochondrion 8.02E-06 GO:0005739 CytoCm Mitochondrion 1.55E+04 ENSG00000179091 CYC1 Mactive_CytoCm Mitochondrion 7.17E-04 GO:0005739 ENSG00000179091 CYC1 CytoCr Mitochondrion 7.16E-03 ENSG00000179091 CYC1 Smacm Mitochondrion 1.47E+03 ENSG00000184047 DIABLO Mactive_Smacm Mitochondrion 6.80E-05 ENSG00000184047 DIABLO Smacr Mitochondrion 5.43E-04 ENSG00000184047 DIABLO CytoC Cytoplasm 5.01E-04 ENSG00000179091 CYC1 Apaf Cytoplasm 5.20E-01 ENSG00000120868 APAF1 CytoC_Apaf Cytoplasm 4.12E-07 ENSG00000179091 ENSG00000120868 CYC1 APAF1 Apafactive Cytoplasm 1.15E-03 ENSG00000120868 APAF1 pC9 Cytoplasm 4.53E+00 ENSG00000169174 PCSK9 Apop Cytoplasm 4.15E-04 ENSG00000169174 ENSG00000120868 PCSK9 APAF1 Apop_C3 Cytoplasm 4.80E-04 ENSG00000169174 ENSG00000120868 ENSG00000164305 ENSG00000165806 PCSK9 APAF1 CASP3 CASP7 Smac Cytoplasm 2.84E-05 ENSG00000184047 DIABLO Apop_XIAP Cytoplasm 1.40E-02 ENSG00000169174 ENSG00000120868 ENSG00000101966 PCSK9 APAF1 XIAP Smac_XIAP Cytoplasm 3.35E-03 ENSG00000184047 ENSG00000101966 DIABLO XIAP C3_Ub Cytoplasm 2.02E+00 ENSG00000164305 ENSG00000165806 CASP3 CASP7 BAD Cytoplasm 9.46E-02 ENSG00000002330 BAD PUMA Cytoplasm 2.91E-02 ENSG00000105327 BBC3 NOXA Cytoplasm 5.55E-03 ENSG00000141682 PMAIP1 Bcl2c_BAD Cytoplasm 3.33E+00 ENSG00000171791 ENSG00000171552 ENSG00000143384 ENSG00000002330 BCL2 BCL2L1 MCL1 BAD Bcl2c_PUMA Cytoplasm 1.02E+00 ENSG00000171791 ENSG00000171552 ENSG00000143384 ENSG00000105327 BCL2 BCL2L1 MCL1 PUMA Bcl2c_NOXA Cytoplasm 1.94E-01 ENSG00000171791 ENSG00000171552 ENSG00000143384 ENSG00000141682 BCL2 BCL2L1 MCL1 NOXA BIM Cytoplasm 6.00E-02 ENSG00000153094 BCL2L11 BIM_Bax Cytoplasm 1.67E-08 ENSG00000153094 ENSG00000087088 BCL2L11 BAX Bcl2c_BIM Cytoplasm 2.12E+00 ENSG00000171791 ENSG00000171552 ENSG00000143384 ENSG00000153094 BCL2 BCL2L1 MCL1 BCL2L11 ppERK_BIM Cytoplasm 6.06E-04 ENSG00000100030 ENSG00000102882 ENSG00000153094 MAPK1 MAPK3 BCL2L11 pBIM Cytoplasm 1.07E-01 ENSG00000153094 BCL2L11 ppAKT_BAD Cytoplasm 3.35E-05 ENSG00000142208 ENSG00000105221 ENSG00000002330 AKT1 AKT2 BAD pBAD Cytoplasm 9.05E-01 ENSG00000002330 BAD ppERK_BAD Cytoplasm 9.56E-04 ENSG00000100030 ENSG00000102882 ENSG00000002330 MAPK1 MAPK3 BAD E Extracellular 9.82E-17 ENSG00000138798 EGF H Extracellular 9.36E-15 ENSG00000157168 NRG1 HGF Extracellular 2.47E-15 ENSG00000019991 HGF P Extracellular 2.86E-19 ENSG00000100311 PDGFB F Extracellular 4.13E-16 ENSG00000113578 ENSG00000138685 FGF1 FGF2 I Extracellular 1.26E-18 ENSG00000017427 ENSG00000167244 IGF1 IGF2 INS Extracellular 8.95E-15 ENSG00000254647 INS E1 Cytoplasm 5.00E+01 ENSG00000146648 EGFR pE1 Cytoplasm 5.05E+00 ENSG00000146648 EGFR E2 Cytoplasm 3.80E+00 ENSG00000141736 ERBB2 pE2 Cytoplasm 3.84E-01 ENSG00000141736 ERBB2 E3 Cytoplasm 1.74E+00 ENSG00000065361 ERBB3 E4 Cytoplasm 8.22E-18 ENSG00000178568 ERBB4 pE4 Cytoplasm 8.30E-19 ENSG00000178568 ERBB4 Ev3 Cytoplasm 4.65E-11 Met Cytoplasm 8.57E+00 ENSG00000105976 MET Pr Cytoplasm 2.30E-01 ENSG00000134853 ENSG00000113721 PDGFRA PDGFRB Fr Cytoplasm 1.87E-01 ENSG00000077782 ENSG00000066468 FGFR1 FGFR2 Ir Cytoplasm 2.18E-02 ENSG00000140443 IGF1R Isr Cytoplasm 2.98E-02 ENSG00000171105 INSR E1E1 Cytoplasm 2.50E+00 ENSG00000146648 EGFR E1E2 Cytoplasm 1.90E-01 ENSG00000146648 ENSG00000141736 EGFR ERBB2 E1E3 Cytoplasm 8.71E-02 ENSG00000146648 ENSG00000065361 EGFR ERBB3 E1E4 Cytoplasm 4.11E-19 ENSG00000146648 ENSG00000178568 EGFR ERBB4 E2E2 Cytoplasm 1.44E-02 ENSG00000141736 ERBB2 E2E3 Cytoplasm 6.61E-03 ENSG00000141736 ENSG00000065361 ERBB2 ERBB3 E2E4 Cytoplasm 3.12E-20 ENSG00000141736 ENSG00000178568 ERBB2 ERBB4 E3E4 Cytoplasm 1.43E-20 ENSG00000065361 ENSG00000178568 ERBB3 E4E4 Cytoplasm 0.00E+00 ENSG00000178568 ERBB4 Met_Met Cytoplasm 7.35E-02 ENSG00000105976 MET FrFr Cytoplasm 3.49E-05 ENSG00000113578 ENSG00000138685 FGF1 FGF2 IrIr Cytoplasm 7.27E-01 ENSG00000140443 IGF1R Isr_Isr Cytoplasm 3.09E-01 ENSG00000171105 INSR EE1 Cytoplasm 1.84E-17 ENSG00000138798 ENSG00000146648 EGF EGFR HE3 Cytoplasm 1.57E-16 ENSG00000157168 ENSG00000065361 NRG1 ERBB3 HE4 Cytoplasm 1.75E-28 ENSG00000157168 ENSG00000178568 NRG1 ERBB4 HGF_Met Cytoplasm 7.66E-14 ENSG00000019991 ENSG00000105976 HGF MET PPr Cytoplasm 6.56E-20 ENSG00000100311 ENSG00000134853 ENSG00000113721 PDGFB PDGFRA PDGFRB FFr Cytoplasm 3.02E-16 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 FGF1 FGF2 FGFR1 FGFR2 EE1E2 Cytoplasm 2.00E-16 ENSG00000138798 ENSG00000146648 ENSG00000141736 EGF EGFR ERBB2 EE1Ev3 Cytoplasm 4.85E-27 ENSG00000138798 ENSG00000146648 EGF EGFR EE1E1 Cytoplasm 5.01E-16 ENSG00000138798 ENSG00000146648 EGF EGFR EE1E3 Cytoplasm 9.09E-17 ENSG00000138798 ENSG00000146648 ENSG00000065361 EGF EGFR ERBB3 EE1E4 Cytoplasm 2.69E-27 ENSG00000138798 ENSG00000146648 ENSG00000178568 EGF EGFR ERBB4 E2HE3 Cytoplasm 5.40E-16 ENSG00000141736 ENSG00000157168 ENSG00000065361 ERBB2 NRG1 ERBB3 E1HE3 Cytoplasm 6.28E-15 ENSG00000146648 ENSG00000157168 ENSG00000065361 EGFR NRG1 ERBB3 HE3E3 Cytoplasm 2.72E-16 ENSG00000157168 ENSG00000065361 NRG1 ERBB3 HE3Ev3 Cytoplasm 7.19E-27 ENSG00000157168 ENSG00000065361 NRG1 ERBB3 HE3E4 Cytoplasm 4.68E-27 ENSG00000157168 ENSG00000065361 ENSG00000178568 NRG1 ERBB3 ERBB4 E2HE4 Cytoplasm 6.44E-28 ENSG00000141736 ENSG00000157168 ENSG00000178568 ERBB2 NRG1 ERBB4 HE4Ev3 Cytoplasm 8.09E-39 ENSG00000157168 ENSG00000178568 NRG1 ERBB4 E1HE4 Cytoplasm 7.12E-27 ENSG00000146648 ENSG00000157168 ENSG00000178568 EGFR NRG1 ERBB4 E3HE4 Cytoplasm 1.97E-27 ENSG00000065361 ENSG00000157168 ENSG00000178568 ERBB3 NRG1 ERBB4 HE4E4 Cytoplasm 1.66E-39 ENSG00000157168 ENSG00000178568 NRG1 ERBB4 HGF_Met_Met Cytoplasm 5.63E-13 ENSG00000019991 ENSG00000105976 HGF MET PPrPr Cytoplasm 4.53E-24 ENSG00000100311 ENSG00000134853 ENSG00000113721 PDGFB PDGFRA PDGFRB FFrFr Cytoplasm 4.94E-16 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 FGF1 FGF2 FGFR1 FGFR2 IIrIr Cytoplasm 5.15E-19 ENSG00000017427 ENSG00000167244 ENSG00000140443 IGF1 IGF2 IGF1R INS_Isr_Isr Cytoplasm 6.87E-17 ENSG00000254647 ENSG00000171105 INS INSR EE1EE1 Cytoplasm 0.00E+00 ENSG00000138798 ENSG00000146648 EGF EGFR EE1HE3 Cytoplasm 4.74E-32 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000065361 EGF EGFR NRG1 ERBB3 EE1HE4 Cytoplasm 8.57E-43 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000178568 EGF EGFR NRG1 ERBB4 HE3HE3 Cytoplasm 9.31E-32 ENSG00000157168 ENSG00000065361 NRG1 ERBB3 HE3HE4 Cytoplasm 2.35E-42 ENSG00000157168 ENSG00000065361 ENSG00000178568 NRG1 ERBB3 ERBB4 HE4HE4 Cytoplasm 0.00E+00 ENSG00000157168 ENSG00000178568 NRG1 ERBB4 HGF_Met_HGF_Met Cytoplasm 1.03E-26 ENSG00000019991 ENSG00000105976 HGF MET PPrPPr Cytoplasm 0.00E+00 ENSG00000100311 ENSG00000134853 ENSG00000113721 PDGFB PDGFRA PDGFRB FFrFFr Cytoplasm 8.11E-30 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 FGF1 FGF2 FGFR1 FGFR2 IIrIrI Cytoplasm 7.61E-38 ENSG00000017427 ENSG00000167244 ENSG00000140443 IGF1 IGF2 IGF1R INS_Isr_Isr_INS Cytoplasm 1.02E-27 ENSG00000254647 ENSG00000171105 INS INSR E1_ppERK Cytoplasm 5.05E-01 ENSG00000146648 ENSG00000100030 ENSG00000102882 EGFR MAPK1 MAPK3 E2_ppERK Cytoplasm 3.84E-02 ENSG00000141736 ENSG00000100030 ENSG00000102882 ERBB2 MAPK1 MAPK3 E4_ppERK Cytoplasm 8.30E-20 ENSG00000178568 ENSG00000100030 ENSG00000102882 ERBB4 MAPK1 MAPK3 pEE1E2 Cytoplasm 1.99E-16 ENSG00000138798 ENSG00000146648 ENSG00000141736 EGF EGFR ERBB2 pEE1Ev3 Cytoplasm 4.84E-27 ENSG00000138798 ENSG00000146648 EGF EGFR pEE1E1 Cytoplasm 4.95E-16 ENSG00000138798 ENSG00000146648 EGF EGFR pEE1EE1 Cytoplasm 0.00E+00 ENSG00000138798 ENSG00000146648 EGF EGFR pEE1E3 Cytoplasm 9.05E-17 ENSG00000138798 ENSG00000146648 ENSG00000065361 EGF EGFR ERBB3 pEE1HE3 Cytoplasm 4.71E-32 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000065361 EGF EGFR NRG1 ERBB3 pEE1E4 Cytoplasm 2.71E-27 ENSG00000138798 ENSG00000146648 ENSG00000178568 EGF EGFR ERBB4 pEE1HE4 Cytoplasm 8.55E-43 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000178568 EGF EGFR NRG1 ERBB4 pE2HE3 Cytoplasm 5.39E-16 ENSG00000141736 ENSG00000157168 ENSG00000065361 ERBB2 NRG1 ERBB3 pHE3Ev3 Cytoplasm 7.19E-27 ENSG00000157168 ENSG00000065361 NRG1 ERBB3 pE1HE3 Cytoplasm 6.26E-15 ENSG00000146648 ENSG00000157168 ENSG00000065361 EGFR NRG1 ERBB3 pHE3E4 Cytoplasm 4.72E-27 ENSG00000157168 ENSG00000065361 ENSG00000178568 NRG1 ERBB3 ERBB4 pHE3HE4 Cytoplasm 2.36E-42 ENSG00000157168 ENSG00000065361 ENSG00000178568 NRG1 ERBB3 ERBB4 pE2HE4 Cytoplasm 6.44E-28 ENSG00000141736 ENSG00000157168 ENSG00000178568 ERBB2 NRG1 ERBB4 pHE4Ev3 Cytoplasm 8.09E-39 ENSG00000157168 ENSG00000178568 NRG1 ERBB4 pE1HE4 Cytoplasm 7.09E-27 ENSG00000146648 ENSG00000157168 ENSG00000178568 EGFR NRG1 ERBB4 pE3HE4 Cytoplasm 1.99E-27 ENSG00000065361 ENSG00000157168 ENSG00000178568 ERBB3 NRG1 ERBB4 pHE4E4 Cytoplasm 1.67E-39 ENSG00000157168 ENSG00000178568 NRG1 ERBB4 pHE4HE4 Cytoplasm 0.00E+00 ENSG00000157168 ENSG00000178568 NRG1 ERBB4 pHGF_Met_Met Cytoplasm 5.62E-13 ENSG00000019991 ENSG00000105976 HGF MET pHGF_Met_HGF_Met Cytoplasm 1.02E-26 ENSG00000019991 ENSG00000105976 HGF MET pPPrPPr Cytoplasm 0.00E+00 ENSG00000100311 ENSG00000134853 ENSG00000113721 PDGFB PDGFRA PDGFRB pPPrPr Cytoplasm 4.52E-24 ENSG00000100311 ENSG00000134853 ENSG00000113721 PDGFB PDGFRA PDGFRB pFFrFFr Cytoplasm 8.14E-30 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 FGF1 FGF2 FGFR1 FGFR2 pFFrFr Cytoplasm 4.94E-16 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 FGF1 FGF2 FGFR1 FGFR2 pIIrIr Cytoplasm 5.15E-19 ENSG00000017427 ENSG00000167244 ENSG00000140443 IGF1 IGF2 IGF1R pINS_Isr_Isr Cytoplasm 6.86E-17 ENSG00000254647 ENSG00000171105 INS INSR pIIrIrI Cytoplasm 7.61E-38 ENSG00000017427 ENSG00000167244 ENSG00000140443 IGF1 IGF2 IGF1R pINS_Isr_Isr_INS Cytoplasm 1.02E-27 ENSG00000254647 ENSG00000171105 INS INSR pIIrIr_IRS Cytoplasm 3.75E-19 ENSG00000017427 ENSG00000167244 ENSG00000140443 ENSG00000169047 ENSG00000185950 IGF1 IGF2 IGF1R IRS1 IRS2 pINS_Isr_Isr_IRS Cytoplasm 4.96E-17 ENSG00000254647 ENSG00000171105 ENSG00000169047 ENSG00000185950 INS INSR IRS1 IRS2 pIIrIrI_IRS Cytoplasm 5.88E-38 ENSG00000017427 ENSG00000167244 ENSG00000140443 ENSG00000197081 ENSG00000169047 ENSG00000185950 IGF1 IGF2 IGF1R IGF2R IRS1 IRS2 pINS_Isr_Isr_INS_IRS Cytoplasm 7.74E-28 ENSG00000254647 ENSG00000171105 ENSG00000169047 ENSG00000185950 INS INSR IRS1 IRS2 Sp_EE1E2 Cytoplasm 3.30E-18 ENSG00000136158 ENSG00000138798 ENSG00000146648 ENSG00000141736 SPRY2 EGF EGFR ERBB2 Sp_EE1Ev3 Cytoplasm 1.19E-28 ENSG00000136158 ENSG00000138798 ENSG00000146648 SPRY2 EGF EGFR Sp_EE1E1 Cytoplasm 8.27E-18 ENSG00000136158 ENSG00000138798 ENSG00000146648 SPRY2 EGF EGFR Sp_EE1EE1 Cytoplasm 0.00E+00 ENSG00000136158 ENSG00000138798 ENSG00000146648 SPRY2 EGF EGFR Sp_EE1E3 Cytoplasm 1.50E-18 ENSG00000136158 ENSG00000138798 ENSG00000146648 ENSG00000065361 SPRY2 EGF EGFR ERBB3 Sp_EE1HE3 Cytoplasm 7.81E-34 ENSG00000136158 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000065361 SPRY2 EGF EGFR NRG1 ERBB3 Sp_EE1E4 Cytoplasm 4.45E-29 ENSG00000136158 ENSG00000138798 ENSG00000146648 ENSG00000178568 SPRY2 EGF EGFR ERBB4 Sp_EE1HE4 Cytoplasm 1.42E-44 ENSG00000136158 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000178568 SPRY2 EGF EGFR NRG1 ERBB4 Sp_E2HE3 Cytoplasm 8.90E-18 ENSG00000136158 ENSG00000141736 ENSG00000157168 ENSG00000065361 SPRY2 ERBB2 NRG1 ERBB3 Sp_HE3Ev3 Cytoplasm 1.19E-28 ENSG00000136158 ENSG00000157168 ENSG00000065361 ENSG00000178568 SPRY2 NRG1 ERBB3 Sp_E1HE3 Cytoplasm 1.04E-16 ENSG00000136158 ENSG00000146648 ENSG00000157168 ENSG00000065361 SPRY2 EGFR NRG1 ERBB3 Sp_HE3E4 Cytoplasm 7.70E-29 ENSG00000136158 ENSG00000157168 ENSG00000065361 ENSG00000178568 SPRY2 NRG1 ERBB3 ERBB4 Sp_HE3HE4 Cytoplasm 3.87E-44 ENSG00000136158 ENSG00000157168 ENSG00000065361 ENSG00000178568 SPRY2 NRG1 ERBB3 ERBB4 Sp_E2HE4 Cytoplasm 1.06E-29 ENSG00000136158 ENSG00000141736 ENSG00000157168 ENSG00000178568 SPRY2 ERBB2 NRG1 ERBB4 Sp_HE4Ev3 Cytoplasm 1.33E-40 ENSG00000136158 ENSG00000157168 ENSG00000178568 SPRY2 NRG1 ERBB4 Sp_E1HE4 Cytoplasm 1.17E-28 ENSG00000136158 ENSG00000146648 ENSG00000157168 ENSG00000178568 SPRY2 EGFR NRG1 ERBB4 Sp_E3HE4 Cytoplasm 3.25E-29 ENSG00000136158 ENSG00000065361 ENSG00000157168 ENSG00000178568 SPRY2 ERBB3 NRG1 ERBB4 Sp_HE4E4 Cytoplasm 2.73E-41 ENSG00000136158 ENSG00000157168 ENSG00000178568 SPRY2 NRG1 ERBB4 Sp_HE4HE4 Cytoplasm 0.00E+00 ENSG00000136158 ENSG00000157168 ENSG00000178568 SPRY2 NRG1 ERBB4 Sp_HGF_Met_Met Cytoplasm 9.28E-15 ENSG00000136158 ENSG00000019991 ENSG00000105976 SPRY2 HGF MET Sp_HGF_Met_HGF_Met Cytoplasm 1.75E-28 ENSG00000136158 ENSG00000019991 ENSG00000105976 SPRY2 HGF MET Sp_PPrPPr Cytoplasm 0.00E+00 ENSG00000136158 ENSG00000100311 ENSG00000134853 ENSG00000113721 SPRY2 PDGFB PDGFRA PDGFRB Sp_PPrPr Cytoplasm 8.91E-26 ENSG00000136158 ENSG00000100311 ENSG00000134853 ENSG00000113721 SPRY2 PDGFB PDGFRA PDGFRB Sp_FFrFFr Cytoplasm 2.27E-31 ENSG00000136158 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 SPRY2 FGF1 FGF2 FGFR1 FGFR2 Sp_FFrFr Cytoplasm 8.15E-18 ENSG00000136158 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 SPRY2 FGF1 FGF2 FGFR1 FGFR2 Sp_IIrIr Cytoplasm 8.49E-21 ENSG00000136158 ENSG00000017427 ENSG00000167244 ENSG00000140443 SPRY2 IGF1 IGF2 IGF1R Sp_INS_Isr_Isr Cytoplasm 1.13E-18 ENSG00000136158 ENSG00000254647 ENSG00000171105 SPRY2 INS INSR Sp_IIrIrI Cytoplasm 1.48E-39 ENSG00000136158 ENSG00000017427 ENSG00000167244 ENSG00000140443 SPRY2 IGF1 IGF2 IGF1R IGF2R Sp_INS_Isr_Isr_INS Cytoplasm 1.84E-29 ENSG00000136158 ENSG00000254647 ENSG00000171105 SPRY2 INS INSR EE1E2int Cytoplasm 7.14E-16 ENSG00000138798 ENSG00000146648 ENSG00000141736 EGF EGFR ERBB2 EE1Ev3int Cytoplasm 4.87E-26 ENSG00000138798 ENSG00000146648 EGF EGFR EE1E1int Cytoplasm 2.47E-15 ENSG00000138798 ENSG00000146648 EGF EGFR EE1EE1int Cytoplasm 0.00E+00 ENSG00000138798 ENSG00000146648 EGF EGFR EE1E3int Cytoplasm 3.24E-16 ENSG00000138798 ENSG00000146648 ENSG00000065361 EGF EGFR ERBB3 EE1HE3int Cytoplasm 1.69E-31 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000065361 EGF EGFR NRG1 ERBB3 EE1E4int Cytoplasm 1.02E-26 ENSG00000138798 ENSG00000146648 ENSG00000178568 EGF EGFR ERBB4 EE1HE4int Cytoplasm 3.11E-42 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000178568 EGF EGFR NRG1 ERBB4 E2HE3int Cytoplasm 2.08E-16 ENSG00000141736 ENSG00000157168 ENSG00000065361 ERBB2 NRG1 ERBB3 HE3Ev3int Cytoplasm 2.78E-27 ENSG00000157168 ENSG00000065361 NRG1 ERBB3 E1HE3int Cytoplasm 2.24E-14 ENSG00000146648 ENSG00000157168 ENSG00000065361 EGFR NRG1 ERBB3 HE3E4int Cytoplasm 1.86E-27 ENSG00000157168 ENSG00000065361 ENSG00000178568 NRG1 ERBB3 ERBB4 HE3HE4int Cytoplasm 9.15E-43 ENSG00000157168 ENSG00000065361 ENSG00000178568 NRG1 ERBB3 ERBB4 E2HE4int Cytoplasm 2.48E-28 ENSG00000141736 ENSG00000157168 ENSG00000178568 ERBB2 NRG1 ERBB4 HE4Ev3int Cytoplasm 3.11E-39 ENSG00000157168 ENSG00000178568 NRG1 ERBB4 E1HE4int Cytoplasm 2.54E-26 ENSG00000146648 ENSG00000157168 ENSG00000178568 EGFR NRG1 ERBB4 E3HE4int Cytoplasm 7.68E-28 ENSG00000065361 ENSG00000157168 ENSG00000178568 ERBB3 NRG1 ERBB4 HE4E4int Cytoplasm 6.44E-40 ENSG00000157168 ENSG00000178568 NRG1 ERBB4 HE4HE4int Cytoplasm 0.00E+00 ENSG00000157168 ENSG00000178568 NRG1 ERBB4 HGF_Met_Metint Cytoplasm 2.17E-13 ENSG00000019991 ENSG00000105976 HGF MET HGF_Met_HGF_Metint Cytoplasm 1.98E-26 ENSG00000019991 ENSG00000105976 HGF MET PPrPPrint Cytoplasm 0.00E+00 ENSG00000100311 ENSG00000134853 ENSG00000113721 PDGFB PDGFRA PDGFRB PPrPrint Cytoplasm 3.25E-24 ENSG00000100311 ENSG00000134853 ENSG00000113721 PDGFB PDGFRA PDGFRB FFrFFrint Cytoplasm 6.34E-30 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 FGF1 FGF2 FGFR1 FGFR2 FFrFrint Cytoplasm 1.91E-16 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 FGF1 FGF2 FGFR1 FGFR2 IIrIr_int Cytoplasm 8.09E-19 ENSG00000017427 ENSG00000167244 ENSG00000140443 IGF1 IGF2 IGF1R INS_Isr_Isr_int Cytoplasm 1.54E-16 ENSG00000254647 ENSG00000171105 INS INSR IIrIrI_int Cytoplasm 3.50E-36 ENSG00000017427 ENSG00000167244 ENSG00000140443 IGF1 IGF2 IGF1R INS_Isr_Isr_INS_int Cytoplasm 3.30E-25 ENSG00000254647 ENSG00000171105 INS INSR pEE1E2int Cytoplasm 7.15E-16 ENSG00000138798 ENSG00000146648 ENSG00000141736 EGF EGFR ERBB2 pEE1Ev3int Cytoplasm 4.88E-26 ENSG00000138798 ENSG00000146648 EGF EGFR pEE1E1int Cytoplasm 2.47E-15 ENSG00000138798 ENSG00000146648 EGF EGFR pEE1EE1int Cytoplasm 0.00E+00 ENSG00000138798 ENSG00000146648 EGF EGFR pEE1E3int Cytoplasm 3.25E-16 ENSG00000138798 ENSG00000146648 ENSG00000065361 EGF EGFR ERBB3 pEE1HE3int Cytoplasm 1.69E-31 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000065361 EGF EGFR NRG1 ERBB3 pEE1E4int Cytoplasm 1.02E-26 ENSG00000138798 ENSG00000146648 ENSG00000178568 EGF EGFR ERBB4 pEE1HE4int Cytoplasm 3.11E-42 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000178568 EGF EGFR NRG1 ERBB4 pE2HE3int Cytoplasm 2.09E-16 ENSG00000141736 ENSG00000157168 ENSG00000065361 ERBB2 NRG1 ERBB3 pHE3Ev3int Cytoplasm 2.78E-27 ENSG00000157168 ENSG00000065361 NRG1 ERBB3 pE1HE3int Cytoplasm 2.25E-14 ENSG00000146648 ENSG00000157168 ENSG00000065361 EGFR NRG1 ERBB3 pHE3E4int Cytoplasm 1.86E-27 ENSG00000157168 ENSG00000065361 ENSG00000178568 NRG1 ERBB3 ERBB4 pHE3HE4int Cytoplasm 9.17E-43 ENSG00000157168 ENSG00000065361 ENSG00000178568 NRG1 ERBB3 ERBB4 pE2HE4int Cytoplasm 2.48E-28 ENSG00000141736 ENSG00000157168 ENSG00000178568 ERBB2 NRG1 ERBB4 pHE4Ev3int Cytoplasm 3.11E-39 ENSG00000157168 ENSG00000178568 NRG1 ERBB4 pE1HE4int Cytoplasm 2.54E-26 ENSG00000146648 ENSG00000157168 ENSG00000178568 EGFR NRG1 ERBB4 pE3HE4int Cytoplasm 7.69E-28 ENSG00000065361 ENSG00000157168 ENSG00000178568 ERBB3 NRG1 ERBB4 pHE4E4int Cytoplasm 6.45E-40 ENSG00000157168 ENSG00000178568 NRG1 ERBB4 pHE4HE4int Cytoplasm 0.00E+00 ENSG00000157168 ENSG00000178568 NRG1 ERBB4 pHGF_Met_Metint Cytoplasm 2.18E-13 ENSG00000019991 ENSG00000105976 HGF MET pHGF_Met_HGF_Metint Cytoplasm 1.99E-26 ENSG00000019991 ENSG00000105976 HGF MET pPPrPPrint Cytoplasm 0.00E+00 ENSG00000100311 ENSG00000134853 ENSG00000113721 PDGFB PDGFRA PDGFRB pPPrPrint Cytoplasm 3.25E-24 ENSG00000100311 ENSG00000134853 ENSG00000113721 PDGFB PDGFRA PDGFRB pFFrFFrint Cytoplasm 6.34E-30 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 FGF1 FGF2 FGFR1 FGFR2 pFFrFrint Cytoplasm 1.91E-16 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 FGF1 FGF2 FGFR1 FGFR2 pIIrIr_int Cytoplasm 8.09E-19 ENSG00000017427 ENSG00000167244 ENSG00000140443 IGF1 IGF2 IGF1R pINS_Isr_Isr_int Cytoplasm 1.54E-16 ENSG00000254647 ENSG00000171105 INS INSR pIIrIrI_int Cytoplasm 3.50E-36 ENSG00000017427 ENSG00000167244 ENSG00000140443 IGF1 IGF2 IGF1R pINS_Isr_Isr_INS_int Cytoplasm 3.30E-25 ENSG00000254647 ENSG00000171105 INS INSR pIIrIr_int_IRS Cytoplasm 6.00E-19 ENSG00000017427 ENSG00000167244 ENSG00000140443 ENSG00000169047 ENSG00000185950 IGF1 IGF2 IGF1R IRS1 IRS2 pINS_Isr_Isr_int_IRS Cytoplasm 1.14E-16 ENSG00000254647 ENSG00000171105 ENSG00000169047 ENSG00000185950 INS INSR IRS1 IRS2 pIIrIrI_int_IRS Cytoplasm 2.62E-36 ENSG00000017427 ENSG00000167244 ENSG00000140443 ENSG00000197081 ENSG00000169047 ENSG00000185950 IGF1 IGF2 IGF1R IGF2R IRS1 IRS2 pINS_Isr_Isr_INS_int_IRS Cytoplasm 2.47E-25 ENSG00000254647 ENSG00000171105 ENSG00000169047 ENSG00000185950 INS INSR IRS1 IRS2 pEE1E2_G2_SOS Cytoplasm 1.92E-19 ENSG00000138798 ENSG00000146648 ENSG00000141736 ENSG00000177885 ENSG00000115904 EGF EGFR ERBB2 GRB2 SOS1 pEE1Ev3_G2_SOS Cytoplasm 1.04E-29 ENSG00000138798 ENSG00000146648 ENSG00000177885 ENSG00000115904 EGF EGFR GRB2 SOS1 pEE1E1_G2_SOS Cytoplasm 5.29E-19 ENSG00000138798 ENSG00000146648 ENSG00000177885 ENSG00000115904 EGF EGFR GRB2 SOS1 pEE1EE1_G2_SOS Cytoplasm 0.00E+00 ENSG00000138798 ENSG00000146648 ENSG00000177885 ENSG00000115904 EGF EGFR GRB2 SOS1 pEE1E3_G2_SOS Cytoplasm 7.74E-20 ENSG00000138798 ENSG00000146648 ENSG00000065361 ENSG00000177885 ENSG00000115904 EGF EGFR ERBB3 GRB2 SOS1 pEE1HE3_G2_SOS Cytoplasm 4.03E-35 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000065361 ENSG00000177885 ENSG00000115904 EGF EGFR NRG1 ERBB3 GRB2 SOS1 pEE1E4_G2_SOS Cytoplasm 3.23E-30 ENSG00000138798 ENSG00000146648 ENSG00000178568 ENSG00000177885 ENSG00000115904 EGF EGFR ERBB4 GRB2 SOS1 pEE1HE4_G2_SOS Cytoplasm 1.19E-45 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000178568 ENSG00000177885 ENSG00000115904 EGF EGFR NRG1 ERBB4 GRB2 SOS1 pE2HE3_G2_SOS Cytoplasm 4.04E-19 ENSG00000141736 ENSG00000157168 ENSG00000065361 ENSG00000177885 ENSG00000115904 ERBB2 NRG1 ERBB3 GRB2 SOS1 pHE3Ev3_G2_SOS Cytoplasm 6.15E-30 ENSG00000157168 ENSG00000065361 ENSG00000177885 ENSG00000115904 NRG1 ERBB3 GRB2 SOS1 pE1HE3_G2_SOS Cytoplasm 5.35E-18 ENSG00000146648 ENSG00000157168 ENSG00000065361 ENSG00000177885 ENSG00000115904 EGFR NRG1 ERBB3 GRB2 SOS1 pHE3E4_G2_SOS Cytoplasm 5.71E-30 ENSG00000157168 ENSG00000065361 ENSG00000178568 ENSG00000177885 ENSG00000115904 NRG1 ERBB3 ERBB4 GRB2 SOS1 pHE3HE4_G2_SOS Cytoplasm 2.52E-45 ENSG00000157168 ENSG00000065361 ENSG00000178568 ENSG00000177885 ENSG00000115904 NRG1 ERBB3 ERBB4 GRB2 SOS1 pE2HE4_G2_SOS Cytoplasm 6.89E-31 ENSG00000141736 ENSG00000157168 ENSG00000178568 ENSG00000177885 ENSG00000115904 ERBB2 NRG1 ERBB4 GRB2 SOS1 pHE4Ev3_G2_SOS Cytoplasm 9.53E-42 ENSG00000157168 ENSG00000178568 ENSG00000177885 ENSG00000115904 NRG1 ERBB4 GRB2 SOS1 pE1HE4_G2_SOS Cytoplasm 8.35E-30 ENSG00000146648 ENSG00000157168 ENSG00000178568 ENSG00000177885 ENSG00000115904 EGFR NRG1 ERBB4 GRB2 SOS1 pE3HE4_G2_SOS Cytoplasm 2.65E-30 ENSG00000065361 ENSG00000157168 ENSG00000178568 ENSG00000177885 ENSG00000115904 ERBB3 NRG1 ERBB4 GRB2 SOS1 pHE4E4_G2_SOS Cytoplasm 2.15E-42 ENSG00000157168 ENSG00000178568 ENSG00000177885 ENSG00000115904 NRG1 ERBB4 GRB2 SOS1 pHE4HE4_G2_SOS Cytoplasm 0.00E+00 ENSG00000157168 ENSG00000178568 ENSG00000177885 ENSG00000115904 NRG1 ERBB4 GRB2 SOS1 pHGF_Met_Met_G2_SOS Cytoplasm 1.20E-16 ENSG00000019991 ENSG00000105976 ENSG00000177885 ENSG00000115904 HGF MET GRB2 SOS1 pHGF_Met_HGF_Met_G2_SOS Cytoplasm 2.10E-30 ENSG00000019991 ENSG00000105976 ENSG00000177885 ENSG00000115904 HGF MET GRB2 SOS1 pPPrPPr_G2_SOS Cytoplasm 2.69E-34 ENSG00000100311 ENSG00000134853 ENSG00000113721 ENSG00000177885 ENSG00000115904 PDGFB PDGFRA PDGFRB GRB2 SOS1 pPPrPr_G2_SOS Cytoplasm 4.84E-28 ENSG00000100311 ENSG00000134853 ENSG00000113721 ENSG00000177885 ENSG00000115904 PDGFB PDGFRA PDGFRB GRB2 SOS1 pFFrFFr_G2_SOS Cytoplasm 8.71E-33 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 ENSG00000177885 ENSG00000115904 FGF1 FGF2 FGFR1 FGFR2 GRB2 SOS1 pFFrFr_G2_SOS Cytoplasm 4.22E-19 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 ENSG00000177885 ENSG00000115904 FGF1 FGF2 FGFR1 FGFR2 GRB2 SOS1 pIIrIr_IRS_G2_SOS Cytoplasm 2.01E-22 ENSG00000017427 ENSG00000167244 ENSG00000140443 ENSG00000177885 ENSG00000115904 IGF1 IGF2 IGF1R GRB2 SOS1 pINS_Isr_Isr_IRS_G2_SOS Cytoplasm 3.71E-20 ENSG00000254647 ENSG00000171105 ENSG00000177885 ENSG00000115904 INS INSR GRB2 SOS1 pIIrIrI_IRS_G2_SOS Cytoplasm 3.49E-41 ENSG00000017427 ENSG00000167244 ENSG00000140443 ENSG00000177885 ENSG00000115904 IGF1 IGF2 IGF1R GRB2 SOS1 pINS_Isr_Isr_INS_IRS_G2_SOS Cytoplasm 6.17E-31 ENSG00000254647 ENSG00000171105 ENSG00000177885 ENSG00000115904 INS INSR GRB2 SOS1 pEE1E2int_G2_SOS Cytoplasm 6.88E-19 ENSG00000138798 ENSG00000146648 ENSG00000141736 ENSG00000177885 ENSG00000115904 EGF EGFR ERBB2 GRB2 SOS1 pEE1Ev3int_G2_SOS Cytoplasm 5.11E-29 ENSG00000138798 ENSG00000146648 ENSG00000177885 ENSG00000115904 EGF EGFR GRB2 SOS1 pEE1E1int_G2_SOS Cytoplasm 2.64E-18 ENSG00000138798 ENSG00000146648 ENSG00000177885 ENSG00000115904 EGF EGFR GRB2 SOS1 pEE1EE1int_G2_SOS Cytoplasm 0.00E+00 ENSG00000138798 ENSG00000146648 ENSG00000177885 ENSG00000115904 EGF EGFR GRB2 SOS1 pEE1E3int_G2_SOS Cytoplasm 2.78E-19 ENSG00000138798 ENSG00000146648 ENSG00000065361 ENSG00000177885 ENSG00000115904 EGF EGFR ERBB3 GRB2 SOS1 pEE1HE3int_G2_SOS Cytoplasm 1.45E-34 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000065361 ENSG00000177885 ENSG00000115904 EGF EGFR NRG1 ERBB3 GRB2 SOS1 pEE1E4int_G2_SOS Cytoplasm 1.17E-29 ENSG00000138798 ENSG00000146648 ENSG00000178568 ENSG00000177885 ENSG00000115904 EGF EGFR ERBB4 GRB2 SOS1 pEE1HE4int_G2_SOS Cytoplasm 3.66E-45 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000178568 ENSG00000177885 ENSG00000115904 EGF EGFR NRG1 ERBB4 GRB2 SOS1 pE2HE3int_G2_SOS Cytoplasm 1.56E-19 ENSG00000141736 ENSG00000157168 ENSG00000065361 ENSG00000177885 ENSG00000115904 ERBB2 NRG1 ERBB3 GRB2 SOS1 pHE3Ev3int_G2_SOS Cytoplasm 2.38E-30 ENSG00000157168 ENSG00000065361 ENSG00000177885 ENSG00000115904 NRG1 ERBB3 GRB2 SOS1 pE1HE3int_G2_SOS Cytoplasm 1.92E-17 ENSG00000146648 ENSG00000157168 ENSG00000065361 ENSG00000177885 ENSG00000115904 EGFR NRG1 ERBB3 GRB2 SOS1 pHE3E4int_G2_SOS Cytoplasm 1.82E-30 ENSG00000157168 ENSG00000065361 ENSG00000178568 ENSG00000177885 ENSG00000115904 NRG1 ERBB3 ERBB4 GRB2 SOS1 pHE3HE4int_G2_SOS Cytoplasm 8.87E-46 ENSG00000157168 ENSG00000065361 ENSG00000178568 ENSG00000177885 ENSG00000115904 NRG1 ERBB3 ERBB4 GRB2 SOS1 pE2HE4int_G2_SOS Cytoplasm 2.66E-31 ENSG00000141736 ENSG00000157168 ENSG00000178568 ENSG00000177885 ENSG00000115904 ERBB2 NRG1 ERBB4 GRB2 SOS1 pHE4Ev3int_G2_SOS Cytoplasm 3.66E-42 ENSG00000157168 ENSG00000178568 ENSG00000177885 ENSG00000115904 NRG1 ERBB4 GRB2 SOS1 pE1HE4int_G2_SOS Cytoplasm 3.00E-29 ENSG00000146648 ENSG00000157168 ENSG00000178568 ENSG00000177885 ENSG00000115904 EGFR NRG1 ERBB4 GRB2 SOS1 pE3HE4int_G2_SOS Cytoplasm 7.41E-31 ENSG00000065361 ENSG00000157168 ENSG00000178568 ENSG00000177885 ENSG00000115904 ERBB3 NRG1 ERBB4 GRB2 SOS1 pHE4E4int_G2_SOS Cytoplasm 8.28E-43 ENSG00000157168 ENSG00000178568 ENSG00000177885 ENSG00000115904 NRG1 ERBB4 GRB2 SOS1 pHE4HE4int_G2_SOS Cytoplasm 0.00E+00 ENSG00000157168 ENSG00000178568 ENSG00000177885 ENSG00000115904 NRG1 ERBB4 GRB2 SOS1 pHGF_Met_Metint_G2_SOS Cytoplasm 4.65E-17 ENSG00000019991 ENSG00000105976 ENSG00000177885 ENSG00000115904 HGF MET GRB2 SOS1 pHGF_Met_HGF_Metint_G2_SOS Cytoplasm 1.40E-29 ENSG00000019991 ENSG00000105976 ENSG00000177885 ENSG00000115904 HGF MET GRB2 SOS1 pPPrPPrint_G2_SOS Cytoplasm 0.00E+00 ENSG00000100311 ENSG00000134853 ENSG00000113721 ENSG00000177885 ENSG00000115904 PDGFB PDGFRA PDGFRB GRB2 SOS1 pPPrPrint_G2_SOS Cytoplasm 3.45E-28 ENSG00000100311 ENSG00000134853 ENSG00000113721 ENSG00000177885 ENSG00000115904 PDGFB PDGFRA PDGFRB GRB2 SOS1 pFFrFFrint_G2_SOS Cytoplasm 5.52E-33 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 ENSG00000177885 ENSG00000115904 FGF1 FGF2 FGFR1 FGFR2 GRB2 SOS1 pFFrFrint_G2_SOS Cytoplasm 1.63E-19 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 ENSG00000177885 ENSG00000115904 FGF1 FGF2 FGFR1 FGFR2 GRB2 SOS1 pIIrIr_int_IRS_G2_SOS Cytoplasm 3.21E-22 ENSG00000017427 ENSG00000167244 ENSG00000140443 ENSG00000177885 ENSG00000115904 IGF1 IGF2 IGF1R GRB2 SOS1 pINS_Isr_Isr_int_IRS_G2_SOS Cytoplasm 8.56E-20 ENSG00000254647 ENSG00000171105 ENSG00000177885 ENSG00000115904 INS INSR GRB2 SOS1 pIIrIrI_int_IRS_G2_SOS Cytoplasm 1.49E-39 ENSG00000017427 ENSG00000167244 ENSG00000140443 ENSG00000177885 ENSG00000115904 IGF1 IGF2 IGF1R GRB2 SOS1 pINS_Isr_Isr_INS_int_IRS_G2_SOS Cytoplasm 1.83E-28 ENSG00000254647 ENSG00000171105 ENSG00000177885 ENSG00000115904 INS INSR GRB2 SOS1 pEE1E2_PLCg Cytoplasm 3.46E-18 ENSG00000138798 ENSG00000146648 ENSG00000141736 ENSG00000124181 ENSG00000197943 EGF EGFR ERBB2 PLCG1 PLCG2 pEE1Ev3_PLCg Cytoplasm 8.51E-29 ENSG00000138798 ENSG00000146648 ENSG00000124181 ENSG00000197943 EGF EGFR PLCG1 PLCG2 pEE1E1_PLCg Cytoplasm 8.59E-18 ENSG00000138798 ENSG00000146648 ENSG00000124181 ENSG00000197943 EGF EGFR PLCG1 PLCG2 pEE1EE1_PLCg Cytoplasm 0.00E+00 ENSG00000138798 ENSG00000146648 ENSG00000124181 ENSG00000197943 EGF EGFR PLCG1 PLCG2 pEE1E3_PLCg Cytoplasm 1.18E-18 ENSG00000138798 ENSG00000146648 ENSG00000065361 ENSG00000124181 ENSG00000197943 EGF EGFR ERBB3 PLCG1 PLCG2 pEE1HE3_PLCg Cytoplasm 6.14E-34 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000065361 ENSG00000124181 ENSG00000197943 EGF EGFR NRG1 ERBB3 PLCG1 PLCG2 pEE1E4_PLCg Cytoplasm 6.04E-29 ENSG00000138798 ENSG00000146648 ENSG00000178568 ENSG00000124181 ENSG00000197943 EGF EGFR ERBB4 PLCG1 PLCG2 pEE1HE4_PLCg Cytoplasm 1.29E-44 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000178568 ENSG00000124181 ENSG00000197943 EGF EGFR NRG1 ERBB4 PLCG1 PLCG2 pE2HE3_PLCg Cytoplasm 7.02E-18 ENSG00000141736 ENSG00000157168 ENSG00000065361 ENSG00000124181 ENSG00000197943 ERBB2 NRG1 ERBB3 PLCG1 PLCG2 pHE3Ev3_PLCg Cytoplasm 9.36E-29 ENSG00000157168 ENSG00000065361 ENSG00000124181 ENSG00000197943 NRG1 ERBB3 PLCG1 PLCG2 pE1HE3_PLCg Cytoplasm 8.14E-17 ENSG00000146648 ENSG00000157168 ENSG00000065361 ENSG00000124181 ENSG00000197943 EGFR NRG1 ERBB3 PLCG1 PLCG2 pHE3E4_PLCg Cytoplasm 4.84E-29 ENSG00000157168 ENSG00000065361 ENSG00000178568 ENSG00000124181 ENSG00000197943 NRG1 ERBB3 ERBB4 PLCG1 PLCG2 pHE3HE4_PLCg Cytoplasm 2.28E-44 ENSG00000157168 ENSG00000065361 ENSG00000178568 ENSG00000124181 ENSG00000197943 NRG1 ERBB3 ERBB4 PLCG1 PLCG2 pE2HE4_PLCg Cytoplasm 8.38E-30 ENSG00000141736 ENSG00000157168 ENSG00000178568 ENSG00000124181 ENSG00000197943 ERBB2 NRG1 ERBB4 PLCG1 PLCG2 pHE4Ev3_PLCg Cytoplasm 1.06E-40 ENSG00000157168 ENSG00000178568 ENSG00000124181 ENSG00000197943 NRG1 ERBB4 PLCG1 PLCG2 pE1HE4_PLCg Cytoplasm 9.64E-29 ENSG00000146648 ENSG00000157168 ENSG00000178568 ENSG00000124181 ENSG00000197943 EGFR NRG1 ERBB4 PLCG1 PLCG2 pE3HE4_PLCg Cytoplasm 2.27E-29 ENSG00000065361 ENSG00000157168 ENSG00000178568 ENSG00000124181 ENSG00000197943 ERBB3 NRG1 ERBB4 PLCG1 PLCG2 pHE4E4_PLCg Cytoplasm 1.50E-41 ENSG00000157168 ENSG00000178568 ENSG00000124181 ENSG00000197943 NRG1 ERBB4 PLCG1 PLCG2 pHE4HE4_PLCg Cytoplasm 0.00E+00 ENSG00000157168 ENSG00000178568 ENSG00000124181 ENSG00000197943 NRG1 ERBB4 PLCG1 PLCG2 pHGF_Met_Met_PLCg Cytoplasm 9.76E-15 ENSG00000019991 ENSG00000105976 ENSG00000124181 ENSG00000197943 HGF MET PLCG1 PLCG2 pHGF_Met_HGF_Met_PLCg Cytoplasm 1.71E-28 ENSG00000019991 ENSG00000105976 ENSG00000124181 ENSG00000197943 HGF MET PLCG1 PLCG2 pPPrPPr_PLCg Cytoplasm 4.31E-32 ENSG00000100311 ENSG00000134853 ENSG00000113721 ENSG00000124181 ENSG00000197943 PDGFB PDGFRA PDGFRB PLCG1 PLCG2 pPPrPr_PLCg Cytoplasm 9.85E-26 ENSG00000100311 ENSG00000134853 ENSG00000113721 ENSG00000124181 ENSG00000197943 PDGFB PDGFRA PDGFRB PLCG1 PLCG2 pFFrFFr_PLCg Cytoplasm 1.55E-31 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 ENSG00000124181 ENSG00000197943 FGF1 FGF2 FGFR1 FGFR2 PLCG1 PLCG2 pFFrFr_PLCg Cytoplasm 1.29E-17 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 ENSG00000124181 ENSG00000197943 FGF1 FGF2 FGFR1 FGFR2 PLCG1 PLCG2 pIIrIr_IRS_PLCg Cytoplasm 2.44E-21 ENSG00000017427 ENSG00000167244 ENSG00000140443 ENSG00000124181 ENSG00000197943 IGF1 IGF2 IGF1R PLCG1 PLCG2 pINS_Isr_Isr_IRS_PLCg Cytoplasm 7.53E-19 ENSG00000254647 ENSG00000171105 ENSG00000124181 ENSG00000197943 INS INSR PLCG1 PLCG2 pIIrIrI_IRS_PLCg Cytoplasm 3.83E-40 ENSG00000017427 ENSG00000167244 ENSG00000140443 ENSG00000124181 ENSG00000197943 IGF1 IGF2 IGF1R PLCG1 PLCG2 pINS_Isr_Isr_INS_IRS_PLCg Cytoplasm 1.18E-29 ENSG00000254647 ENSG00000171105 ENSG00000124181 ENSG00000197943 INS INSR PLCG1 PLCG2 pEE1E2_PI3K1 Cytoplasm 2.28E-17 ENSG00000138798 ENSG00000146648 ENSG00000141736 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 EGF EGFR ERBB2 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pEE1Ev3_PI3K1 Cytoplasm 2.97E-28 ENSG00000138798 ENSG00000146648 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 EGF EGFR PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pEE1E1_PI3K1 Cytoplasm 2.84E-17 ENSG00000138798 ENSG00000146648 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 EGF EGFR PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R5 pEE1EE1_PI3K1 Cytoplasm 0.00E+00 ENSG00000138798 ENSG00000146648 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 EGF EGFR PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R6 pEE1E3_PI3K1 Cytoplasm 2.59E-17 ENSG00000138798 ENSG00000146648 ENSG00000065361 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 EGF EGFR ERBB3 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pEE1HE3_PI3K1 Cytoplasm 1.35E-32 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000065361 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 EGF EGFR NRG1 ERBB3 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pEE1E4_PI3K1 Cytoplasm 6.05E-28 ENSG00000138798 ENSG00000146648 ENSG00000178568 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 EGF EGFR ERBB4 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pEE1HE4_PI3K1 Cytoplasm 1.04E-43 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000178568 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 EGF EGFR NRG1 ERBB4 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pE2HE3_PI3K1 Cytoplasm 1.86E-16 ENSG00000141736 ENSG00000157168 ENSG00000065361 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 ERBB2 NRG1 ERBB3 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pHE3Ev3_PI3K1 Cytoplasm 2.06E-27 ENSG00000157168 ENSG00000065361 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 NRG1 ERBB3 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pE1HE3_PI3K1 Cytoplasm 1.79E-15 ENSG00000146648 ENSG00000157168 ENSG00000065361 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 EGFR NRG1 ERBB3 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pHE3E4_PI3K1 Cytoplasm 2.18E-27 ENSG00000157168 ENSG00000065361 ENSG00000178568 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 NRG1 ERBB3 ERBB4 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pHE3HE4_PI3K1 Cytoplasm 8.03E-43 ENSG00000157168 ENSG00000065361 ENSG00000178568 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 NRG1 ERBB3 ERBB4 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pE2HE4_PI3K1 Cytoplasm 1.18E-28 ENSG00000141736 ENSG00000157168 ENSG00000178568 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 ERBB2 NRG1 ERBB4 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pHE4Ev3_PI3K1 Cytoplasm 9.30E-40 ENSG00000157168 ENSG00000178568 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 NRG1 ERBB4 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pE1HE4_PI3K1 Cytoplasm 8.13E-28 ENSG00000146648 ENSG00000157168 ENSG00000178568 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 EGFR NRG1 ERBB4 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pE3HE4_PI3K1 Cytoplasm 9.17E-28 ENSG00000065361 ENSG00000157168 ENSG00000178568 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 ERBB3 NRG1 ERBB4 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pHE4E4_PI3K1 Cytoplasm 2.96E-40 ENSG00000157168 ENSG00000178568 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 NRG1 ERBB4 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pHE4HE4_PI3K1 Cytoplasm 0.00E+00 ENSG00000157168 ENSG00000178568 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 NRG1 ERBB4 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pHGF_Met_Met_PI3K1 Cytoplasm 9.68E-14 ENSG00000019991 ENSG00000105976 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 HGF MET PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pHGF_Met_HGF_Met_PI3K1 Cytoplasm 1.69E-27 ENSG00000019991 ENSG00000105976 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 HGF MET PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pPPrPPr_PI3K1 Cytoplasm 2.86E-31 ENSG00000100311 ENSG00000134853 ENSG00000113721 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 PDGFB PDGFRA PDGFRB PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pPPrPr_PI3K1 Cytoplasm 7.97E-25 ENSG00000100311 ENSG00000134853 ENSG00000113721 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 PDGFB PDGFRA PDGFRB PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pFFrFFr_PI3K1 Cytoplasm 3.42E-30 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 FGF1 FGF2 FGFR1 FGFR2 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pFFrFr_PI3K1 Cytoplasm 2.27E-16 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 FGF1 FGF2 FGFR1 FGFR2 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pIIrIr_IRS_PI3K1 Cytoplasm 1.12E-19 ENSG00000017427 ENSG00000167244 ENSG00000140443 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 IGF1 IGF2 IGF1R PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pINS_Isr_Isr_IRS_PI3K1 Cytoplasm 2.05E-17 ENSG00000254647 ENSG00000171105 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 INS INSR PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pIIrIrI_IRS_PI3K1 Cytoplasm 1.79E-38 ENSG00000017427 ENSG00000167244 ENSG00000140443 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 IGF1 IGF2 IGF1R PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pINS_Isr_Isr_INS_IRS_PI3K1 Cytoplasm 3.24E-28 ENSG00000254647 ENSG00000171105 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 INS INSR PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pEE1E2_PI3K2 Cytoplasm 1.96E-17 ENSG00000138798 ENSG00000146648 ENSG00000141736 ENSG00000011405 EGF EGFR ERBB2 PIK3C2A pEE1Ev3_PI3K2 Cytoplasm 2.40E-28 ENSG00000138798 ENSG00000146648 ENSG00000011405 EGF EGFR PIK3C2A pEE1E1_PI3K2 Cytoplasm 2.44E-17 ENSG00000138798 ENSG00000146648 ENSG00000011405 EGF EGFR PIK3C2A pEE1EE1_PI3K2 Cytoplasm 0.00E+00 ENSG00000138798 ENSG00000146648 ENSG00000011405 EGF EGFR PIK3C2A pEE1E3_PI3K2 Cytoplasm 2.23E-17 ENSG00000138798 ENSG00000146648 ENSG00000065361 ENSG00000011405 EGF EGFR ERBB3 PIK3C2A pEE1HE3_PI3K2 Cytoplasm 1.16E-32 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000065361 ENSG00000011405 EGF EGFR NRG1 ERBB3 PIK3C2A pEE1E4_PI3K2 Cytoplasm 2.67E-28 ENSG00000138798 ENSG00000146648 ENSG00000178568 ENSG00000011405 EGF EGFR ERBB4 PIK3C2A pEE1HE4_PI3K2 Cytoplasm 8.42E-44 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000178568 ENSG00000011405 EGF EGFR NRG1 ERBB4 PIK3C2A pE2HE3_PI3K2 Cytoplasm 1.59E-16 ENSG00000141736 ENSG00000157168 ENSG00000065361 ENSG00000011405 ERBB2 NRG1 ERBB3 PIK3C2A pHE3Ev3_PI3K2 Cytoplasm 1.77E-27 ENSG00000157168 ENSG00000065361 ENSG00000011405 NRG1 ERBB3 PIK3C2A pE1HE3_PI3K2 Cytoplasm 1.54E-15 ENSG00000146648 ENSG00000157168 ENSG00000065361 ENSG00000011405 EGFR NRG1 ERBB3 PIK3C2A pHE3E4_PI3K2 Cytoplasm 1.42E-27 ENSG00000157168 ENSG00000065361 ENSG00000178568 ENSG00000011405 NRG1 ERBB3 ERBB4 PIK3C2A pHE3HE4_PI3K2 Cytoplasm 7.96E-43 ENSG00000157168 ENSG00000065361 ENSG00000178568 ENSG00000011405 NRG1 ERBB3 ERBB4 PIK3C2A pE2HE4_PI3K2 Cytoplasm 9.52E-29 ENSG00000141736 ENSG00000157168 ENSG00000178568 ENSG00000011405 ERBB2 NRG1 ERBB4 PIK3C2A pHE4Ev3_PI3K2 Cytoplasm 7.96E-40 ENSG00000157168 ENSG00000178568 ENSG00000011405 NRG1 ERBB4 PIK3C2A pE1HE4_PI3K2 Cytoplasm 6.98E-28 ENSG00000146648 ENSG00000157168 ENSG00000178568 ENSG00000011405 EGFR NRG1 ERBB4 PIK3C2A pE3HE4_PI3K2 Cytoplasm 5.60E-28 ENSG00000065361 ENSG00000157168 ENSG00000178568 ENSG00000011405 ERBB3 NRG1 ERBB4 PIK3C2A pHE4E4_PI3K2 Cytoplasm 2.49E-40 ENSG00000157168 ENSG00000178568 ENSG00000011405 NRG1 ERBB4 PIK3C2A pHE4HE4_PI3K2 Cytoplasm 0.00E+00 ENSG00000157168 ENSG00000178568 ENSG00000011405 NRG1 ERBB4 PIK3C2A pHGF_Met_Met_PI3K2 Cytoplasm 8.31E-14 ENSG00000019991 ENSG00000105976 ENSG00000011405 HGF MET PIK3C2A pHGF_Met_HGF_Met_PI3K2 Cytoplasm 1.43E-27 ENSG00000019991 ENSG00000105976 ENSG00000011405 HGF MET PIK3C2A pPPrPPr_PI3K2 Cytoplasm 1.74E-31 ENSG00000100311 ENSG00000134853 ENSG00000113721 ENSG00000011405 PDGFB PDGFRA PDGFRB PIK3C2A pPPrPr_PI3K2 Cytoplasm 6.70E-25 ENSG00000100311 ENSG00000134853 ENSG00000113721 ENSG00000011405 PDGFB PDGFRA PDGFRB PIK3C2A pFFrFFr_PI3K2 Cytoplasm 2.30E-30 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 ENSG00000011405 FGF1 FGF2 FGFR1 FGFR2 PIK3C2A pFFrFr_PI3K2 Cytoplasm 1.94E-16 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 ENSG00000011405 FGF1 FGF2 FGFR1 FGFR2 PIK3C2A pIIrIr_IRS_PI3K2 Cytoplasm 9.69E-20 ENSG00000017427 ENSG00000167244 ENSG00000140443 ENSG00000011405 IGF1 IGF2 IGF1R PIK3C2A pINS_Isr_Isr_IRS_PI3K2 Cytoplasm 1.77E-17 ENSG00000254647 ENSG00000171105 ENSG00000011405 INS INSR PIK3C2A pIIrIrI_IRS_PI3K2 Cytoplasm 1.52E-38 ENSG00000017427 ENSG00000167244 ENSG00000140443 ENSG00000011405 IGF1 IGF2 IGF1R PIK3C2A pINS_Isr_Isr_INS_IRS_PI3K2 Cytoplasm 2.76E-28 ENSG00000254647 ENSG00000171105 ENSG00000011405 INS INSR PIK3C2A pEE1E2int_G2_SOS_RasD Cytoplasm 1.10E-19 ENSG00000138798 ENSG00000146648 ENSG00000141736 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 EGF EGFR ERBB2 GRB2 SOS1 NRAS KRAS HRAS pEE1Ev3int_G2_SOS_RasD Cytoplasm 5.46E-30 ENSG00000138798 ENSG00000146648 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 EGF EGFR GRB2 SOS1 NRAS KRAS HRAS pEE1E1int_G2_SOS_RasD Cytoplasm 4.22E-19 ENSG00000138798 ENSG00000146648 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 EGF EGFR GRB2 SOS1 NRAS KRAS HRAS pEE1EE1int_G2_SOS_RasD Cytoplasm 0.00E+00 ENSG00000138798 ENSG00000146648 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 EGF EGFR GRB2 SOS1 NRAS KRAS HRAS pEE1E3int_G2_SOS_RasD Cytoplasm 4.44E-20 ENSG00000138798 ENSG00000146648 ENSG00000065361 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 EGF EGFR ERBB3 GRB2 SOS1 NRAS KRAS HRAS pEE1HE3int_G2_SOS_RasD Cytoplasm 2.31E-35 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000065361 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 EGF EGFR NRG1 ERBB3 GRB2 SOS1 NRAS KRAS HRAS pEE1E4int_G2_SOS_RasD Cytoplasm 1.18E-30 ENSG00000138798 ENSG00000146648 ENSG00000178568 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 EGF EGFR ERBB4 GRB2 SOS1 NRAS KRAS HRAS pEE1HE4int_G2_SOS_RasD Cytoplasm 5.85E-46 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000178568 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 EGF EGFR NRG1 ERBB4 GRB2 SOS1 NRAS KRAS HRAS pE2HE3int_G2_SOS_RasD Cytoplasm 2.49E-20 ENSG00000141736 ENSG00000157168 ENSG00000065361 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 ERBB2 NRG1 ERBB3 GRB2 SOS1 NRAS KRAS HRAS pHE3Ev3int_G2_SOS_RasD Cytoplasm 3.80E-31 ENSG00000157168 ENSG00000065361 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 NRG1 ERBB3 GRB2 SOS1 NRAS KRAS HRAS pE1HE3int_G2_SOS_RasD Cytoplasm 3.07E-18 ENSG00000146648 ENSG00000157168 ENSG00000065361 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 EGFR NRG1 ERBB3 GRB2 SOS1 NRAS KRAS HRAS pHE3E4int_G2_SOS_RasD Cytoplasm 3.58E-31 ENSG00000157168 ENSG00000065361 ENSG00000178568 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 NRG1 ERBB3 ERBB4 GRB2 SOS1 NRAS KRAS HRAS pHE3HE4int_G2_SOS_RasD Cytoplasm 1.54E-46 ENSG00000157168 ENSG00000065361 ENSG00000178568 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 NRG1 ERBB3 ERBB4 GRB2 SOS1 NRAS KRAS HRAS pE2HE4int_G2_SOS_RasD Cytoplasm 4.29E-32 ENSG00000141736 ENSG00000157168 ENSG00000178568 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 ERBB2 NRG1 ERBB4 GRB2 SOS1 NRAS KRAS HRAS pHE4Ev3int_G2_SOS_RasD Cytoplasm 5.85E-43 ENSG00000157168 ENSG00000178568 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 NRG1 ERBB4 GRB2 SOS1 NRAS KRAS HRAS pE1HE4int_G2_SOS_RasD Cytoplasm 4.98E-30 ENSG00000146648 ENSG00000157168 ENSG00000178568 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 EGFR NRG1 ERBB4 GRB2 SOS1 NRAS KRAS HRAS pE3HE4int_G2_SOS_RasD Cytoplasm 1.21E-31 ENSG00000065361 ENSG00000157168 ENSG00000178568 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 ERBB3 NRG1 ERBB4 GRB2 SOS1 NRAS KRAS HRAS pHE4E4int_G2_SOS_RasD Cytoplasm 1.32E-43 ENSG00000157168 ENSG00000178568 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 NRG1 ERBB4 GRB2 SOS1 NRAS KRAS HRAS pHE4HE4int_G2_SOS_RasD Cytoplasm 0.00E+00 ENSG00000157168 ENSG00000178568 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 NRG1 ERBB4 GRB2 SOS1 NRAS KRAS HRAS pHGF_Met_Metint_G2_SOS_RasD Cytoplasm 7.43E-18 ENSG00000019991 ENSG00000105976 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 HGF MET GRB2 SOS1 NRAS KRAS HRAS pHGF_Met_HGF_Metint_G2_SOS_RasD Cytoplasm 2.63E-31 ENSG00000019991 ENSG00000105976 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 HGF MET GRB2 SOS1 NRAS KRAS HRAS pPPrPPrint_G2_SOS_RasD Cytoplasm 3.44E-31 ENSG00000100311 ENSG00000134853 ENSG00000113721 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 PDGFB PDGFRA PDGFRB GRB2 SOS1 NRAS KRAS HRAS pPPrPrint_G2_SOS_RasD Cytoplasm 5.47E-29 ENSG00000100311 ENSG00000134853 ENSG00000113721 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 PDGFB PDGFRA PDGFRB GRB2 SOS1 NRAS KRAS HRAS pFFrFFrint_G2_SOS_RasD Cytoplasm 1.11E-33 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 FGF1 FGF2 FGFR1 FGFR2 GRB2 SOS1 NRAS KRAS HRAS pFFrFrint_G2_SOS_RasD Cytoplasm 2.61E-20 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 FGF1 FGF2 FGFR1 FGFR2 GRB2 SOS1 NRAS KRAS HRAS pIIrIr_int_IRS_G2_SOS_RasD Cytoplasm 5.13E-23 ENSG00000017427 ENSG00000167244 ENSG00000140443 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 IGF1 IGF2 IGF1R GRB2 SOS1 NRAS KRAS HRAS pINS_Isr_Isr_int_IRS_G2_SOS_RasD Cytoplasm 1.37E-20 ENSG00000254647 ENSG00000171105 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 INS INSR GRB2 SOS1 NRAS KRAS HRAS pIIrIrI_int_IRS_G2_SOS_RasD Cytoplasm 2.38E-40 ENSG00000017427 ENSG00000167244 ENSG00000140443 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 IGF1 IGF2 IGF1R GRB2 SOS1 NRAS KRAS HRAS pINS_Isr_Isr_INS_int_IRS_G2_SOS_RasD Cytoplasm 2.45E-29 ENSG00000254647 ENSG00000171105 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 INS INSR GRB2 SOS1 NRAS KRAS HRAS pEE1E2_G2_SOS_RasD Cytoplasm 1.55E-18 ENSG00000138798 ENSG00000146648 ENSG00000141736 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 EGF EGFR ERBB2 GRB2 SOS1 NRAS KRAS HRAS pEE1Ev3_G2_SOS_RasD Cytoplasm 8.49E-29 ENSG00000138798 ENSG00000146648 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 EGF EGFR GRB2 SOS1 NRAS KRAS HRAS pEE1E1_G2_SOS_RasD Cytoplasm 4.27E-18 ENSG00000138798 ENSG00000146648 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 EGF EGFR GRB2 SOS1 NRAS KRAS HRAS pEE1EE1_G2_SOS_RasD Cytoplasm 0.00E+00 ENSG00000138798 ENSG00000146648 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 EGF EGFR GRB2 SOS1 NRAS KRAS HRAS pEE1E3_G2_SOS_RasD Cytoplasm 6.24E-19 ENSG00000138798 ENSG00000146648 ENSG00000065361 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 EGF EGFR ERBB3 GRB2 SOS1 NRAS KRAS HRAS pEE1HE3_G2_SOS_RasD Cytoplasm 3.25E-34 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000065361 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 EGF EGFR NRG1 ERBB3 GRB2 SOS1 NRAS KRAS HRAS pEE1E4_G2_SOS_RasD Cytoplasm 2.60E-29 ENSG00000138798 ENSG00000146648 ENSG00000178568 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 EGF EGFR ERBB4 GRB2 SOS1 NRAS KRAS HRAS pEE1HE4_G2_SOS_RasD Cytoplasm 9.61E-45 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000178568 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 EGF EGFR NRG1 ERBB4 GRB2 SOS1 NRAS KRAS HRAS pE2HE3_G2_SOS_RasD Cytoplasm 3.26E-18 ENSG00000141736 ENSG00000157168 ENSG00000065361 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 ERBB2 NRG1 ERBB3 GRB2 SOS1 NRAS KRAS HRAS pHE3Ev3_G2_SOS_RasD Cytoplasm 4.96E-29 ENSG00000157168 ENSG00000065361 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 NRG1 ERBB3 GRB2 SOS1 NRAS KRAS HRAS pE1HE3_G2_SOS_RasD Cytoplasm 4.32E-17 ENSG00000146648 ENSG00000157168 ENSG00000065361 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 EGFR NRG1 ERBB3 GRB2 SOS1 NRAS KRAS HRAS pHE3E4_G2_SOS_RasD Cytoplasm 4.62E-29 ENSG00000157168 ENSG00000065361 ENSG00000178568 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 NRG1 ERBB3 ERBB4 GRB2 SOS1 NRAS KRAS HRAS pHE3HE4_G2_SOS_RasD Cytoplasm 2.03E-44 ENSG00000157168 ENSG00000065361 ENSG00000178568 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 NRG1 ERBB3 ERBB4 GRB2 SOS1 NRAS KRAS HRAS pE2HE4_G2_SOS_RasD Cytoplasm 5.56E-30 ENSG00000141736 ENSG00000157168 ENSG00000178568 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 ERBB2 NRG1 ERBB4 GRB2 SOS1 NRAS KRAS HRAS pHE4Ev3_G2_SOS_RasD Cytoplasm 7.69E-41 ENSG00000157168 ENSG00000178568 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 NRG1 ERBB4 GRB2 SOS1 NRAS KRAS HRAS pE1HE4_G2_SOS_RasD Cytoplasm 6.74E-29 ENSG00000146648 ENSG00000157168 ENSG00000178568 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 EGFR NRG1 ERBB4 GRB2 SOS1 NRAS KRAS HRAS pE3HE4_G2_SOS_RasD Cytoplasm 2.14E-29 ENSG00000065361 ENSG00000157168 ENSG00000178568 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 ERBB3 NRG1 ERBB4 GRB2 SOS1 NRAS KRAS HRAS pHE4E4_G2_SOS_RasD Cytoplasm 1.74E-41 ENSG00000157168 ENSG00000178568 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 NRG1 ERBB4 GRB2 SOS1 NRAS KRAS HRAS pHE4HE4_G2_SOS_RasD Cytoplasm 0.00E+00 ENSG00000157168 ENSG00000178568 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 NRG1 ERBB4 GRB2 SOS1 NRAS KRAS HRAS pHGF_Met_Met_G2_SOS_RasD Cytoplasm 9.70E-16 ENSG00000019991 ENSG00000105976 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 HGF MET GRB2 SOS1 NRAS KRAS HRAS pHGF_Met_HGF_Met_G2_SOS_RasD Cytoplasm 1.69E-29 ENSG00000019991 ENSG00000105976 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 HGF MET GRB2 SOS1 NRAS KRAS HRAS pPPrPPr_G2_SOS_RasD Cytoplasm 2.24E-33 ENSG00000100311 ENSG00000134853 ENSG00000113721 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 PDGFB PDGFRA PDGFRB GRB2 SOS1 NRAS KRAS HRAS pPPrPr_G2_SOS_RasD Cytoplasm 3.90E-27 ENSG00000100311 ENSG00000134853 ENSG00000113721 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 PDGFB PDGFRA PDGFRB GRB2 SOS1 NRAS KRAS HRAS pFFrFFr_G2_SOS_RasD Cytoplasm 7.05E-32 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 FGF1 FGF2 FGFR1 FGFR2 GRB2 SOS1 NRAS KRAS HRAS pFFrFr_G2_SOS_RasD Cytoplasm 3.41E-18 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 FGF1 FGF2 FGFR1 FGFR2 GRB2 SOS1 NRAS KRAS HRAS pIIrIr_IRS_G2_SOS_RasD Cytoplasm 1.62E-21 ENSG00000017427 ENSG00000167244 ENSG00000140443 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 IGF1 IGF2 IGF1R GRB2 SOS1 NRAS KRAS HRAS pINS_Isr_Isr_IRS_G2_SOS_RasD Cytoplasm 2.99E-19 ENSG00000254647 ENSG00000171105 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 INS INSR GRB2 SOS1 NRAS KRAS HRAS pIIrIrI_IRS_G2_SOS_RasD Cytoplasm 2.80E-40 ENSG00000017427 ENSG00000167244 ENSG00000140443 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 IGF1 IGF2 IGF1R GRB2 SOS1 NRAS KRAS HRAS pINS_Isr_Isr_INS_IRS_G2_SOS_RasD Cytoplasm 4.98E-30 ENSG00000254647 ENSG00000171105 ENSG00000177885 ENSG00000115904 ENSG00000213281 ENSG00000133703 ENSG00000174775 INS INSR GRB2 SOS1 NRAS KRAS HRAS pEE1E2_PLCg_PIP2 Cytoplasm 3.14E-17 ENSG00000138798 ENSG00000146648 ENSG00000141736 ENSG00000124181 ENSG00000197943 EGF EGFR ERBB2 PLCG1 PLCG2 pEE1Ev3_PLCg_PIP2 Cytoplasm 7.74E-28 ENSG00000138798 ENSG00000146648 ENSG00000124181 ENSG00000197943 EGF EGFR PLCG1 PLCG2 pEE1E1_PLCg_PIP2 Cytoplasm 7.81E-17 ENSG00000138798 ENSG00000146648 ENSG00000124181 ENSG00000197943 EGF EGFR PLCG1 PLCG2 pEE1EE1_PLCg_PIP2 Cytoplasm 0.00E+00 ENSG00000138798 ENSG00000146648 ENSG00000124181 ENSG00000197943 EGF EGFR PLCG1 PLCG2 pEE1E3_PLCg_PIP2 Cytoplasm 1.07E-17 ENSG00000138798 ENSG00000146648 ENSG00000065361 ENSG00000124181 ENSG00000197943 EGF EGFR ERBB3 PLCG1 PLCG2 pEE1HE3_PLCg_PIP2 Cytoplasm 5.58E-33 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000065361 ENSG00000124181 ENSG00000197943 EGF EGFR NRG1 ERBB3 PLCG1 PLCG2 pEE1E4_PLCg_PIP2 Cytoplasm 5.60E-28 ENSG00000138798 ENSG00000146648 ENSG00000178568 ENSG00000124181 ENSG00000197943 EGF EGFR ERBB4 PLCG1 PLCG2 pEE1HE4_PLCg_PIP2 Cytoplasm 1.18E-43 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000178568 ENSG00000124181 ENSG00000197943 EGF EGFR NRG1 ERBB4 PLCG1 PLCG2 pE2HE3_PLCg_PIP2 Cytoplasm 6.38E-17 ENSG00000141736 ENSG00000157168 ENSG00000065361 ENSG00000124181 ENSG00000197943 ERBB2 NRG1 ERBB3 PLCG1 PLCG2 pHE3Ev3_PLCg_PIP2 Cytoplasm 8.51E-28 ENSG00000157168 ENSG00000065361 ENSG00000124181 ENSG00000197943 NRG1 ERBB3 PLCG1 PLCG2 pE1HE3_PLCg_PIP2 Cytoplasm 7.40E-16 ENSG00000146648 ENSG00000157168 ENSG00000065361 ENSG00000124181 ENSG00000197943 EGFR NRG1 ERBB3 PLCG1 PLCG2 pHE3E4_PLCg_PIP2 Cytoplasm 4.43E-28 ENSG00000157168 ENSG00000065361 ENSG00000178568 ENSG00000124181 ENSG00000197943 NRG1 ERBB3 ERBB4 PLCG1 PLCG2 pHE3HE4_PLCg_PIP2 Cytoplasm 2.09E-43 ENSG00000157168 ENSG00000065361 ENSG00000178568 ENSG00000124181 ENSG00000197943 NRG1 ERBB3 ERBB4 PLCG1 PLCG2 pE2HE4_PLCg_PIP2 Cytoplasm 7.61E-29 ENSG00000141736 ENSG00000157168 ENSG00000178568 ENSG00000124181 ENSG00000197943 ERBB2 NRG1 ERBB4 PLCG1 PLCG2 pHE4Ev3_PLCg_PIP2 Cytoplasm 9.60E-40 ENSG00000157168 ENSG00000178568 ENSG00000124181 ENSG00000197943 NRG1 ERBB4 PLCG1 PLCG2 pE1HE4_PLCg_PIP2 Cytoplasm 8.78E-28 ENSG00000146648 ENSG00000157168 ENSG00000178568 ENSG00000124181 ENSG00000197943 EGFR NRG1 ERBB4 PLCG1 PLCG2 pE3HE4_PLCg_PIP2 Cytoplasm 2.09E-28 ENSG00000065361 ENSG00000157168 ENSG00000178568 ENSG00000124181 ENSG00000197943 ERBB3 NRG1 ERBB4 PLCG1 PLCG2 pHE4E4_PLCg_PIP2 Cytoplasm 1.36E-40 ENSG00000157168 ENSG00000178568 ENSG00000124181 ENSG00000197943 NRG1 ERBB4 PLCG1 PLCG2 pHE4HE4_PLCg_PIP2 Cytoplasm 0.00E+00 ENSG00000157168 ENSG00000178568 ENSG00000124181 ENSG00000197943 NRG1 ERBB4 PLCG1 PLCG2 pHGF_Met_Met_PLCg_PIP2 Cytoplasm 8.88E-14 ENSG00000019991 ENSG00000105976 ENSG00000124181 ENSG00000197943 HGF MET PLCG1 PLCG2 pHGF_Met_HGF_Met_PLCg_PIP2 Cytoplasm 1.55E-27 ENSG00000019991 ENSG00000105976 ENSG00000124181 ENSG00000197943 HGF MET PLCG1 PLCG2 pPPrPPr_PLCg_PIP2 Cytoplasm 3.92E-31 ENSG00000100311 ENSG00000134853 ENSG00000113721 ENSG00000124181 ENSG00000197943 PDGFB PDGFRA PDGFRB PLCG1 PLCG2 pPPrPr_PLCg_PIP2 Cytoplasm 8.95E-25 ENSG00000100311 ENSG00000134853 ENSG00000113721 ENSG00000124181 ENSG00000197943 PDGFB PDGFRA PDGFRB PLCG1 PLCG2 pFFrFFr_PLCg_PIP2 Cytoplasm 1.45E-30 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 ENSG00000124181 ENSG00000197943 FGF1 FGF2 FGFR1 FGFR2 PLCG1 PLCG2 pFFrFr_PLCg_PIP2 Cytoplasm 1.17E-16 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 ENSG00000124181 ENSG00000197943 FGF1 FGF2 FGFR1 FGFR2 PLCG1 PLCG2 pIIrIr_IRS_PLCg_PIP2 Cytoplasm 2.22E-20 ENSG00000017427 ENSG00000167244 ENSG00000140443 ENSG00000124181 ENSG00000197943 IGF1 IGF2 IGF1R PLCG1 PLCG2 pINS_Isr_Isr_IRS_PLCg_PIP2 Cytoplasm 6.84E-18 ENSG00000254647 ENSG00000171105 ENSG00000124181 ENSG00000197943 INS INSR PLCG1 PLCG2 pIIrIrI_IRS_PLCg_PIP2 Cytoplasm 3.48E-39 ENSG00000017427 ENSG00000167244 ENSG00000140443 ENSG00000124181 ENSG00000197943 IGF1 IGF2 IGF1R PLCG1 PLCG2 pINS_Isr_Isr_INS_IRS_PLCg_PIP2 Cytoplasm 1.07E-28 ENSG00000254647 ENSG00000171105 ENSG00000124181 ENSG00000197943 INS INSR PLCG1 PLCG2 pEE1E2_PI3K1_PIP2 Cytoplasm 2.26E-16 ENSG00000138798 ENSG00000146648 ENSG00000141736 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 EGF EGFR ERBB2 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pEE1Ev3_PI3K1_PIP2 Cytoplasm 2.94E-27 ENSG00000138798 ENSG00000146648 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 EGF EGFR PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pEE1E1_PI3K1_PIP2 Cytoplasm 2.81E-16 ENSG00000138798 ENSG00000146648 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 EGF EGFR PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pEE1EE1_PI3K1_PIP2 Cytoplasm 0.00E+00 ENSG00000138798 ENSG00000146648 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 EGF EGFR PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pEE1E3_PI3K1_PIP2 Cytoplasm 2.57E-16 ENSG00000138798 ENSG00000146648 ENSG00000065361 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 EGF EGFR ERBB3 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pEE1HE3_PI3K1_PIP2 Cytoplasm 1.34E-31 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000065361 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 EGF EGFR NRG1 ERBB3 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pEE1E4_PI3K1_PIP2 Cytoplasm 6.01E-27 ENSG00000138798 ENSG00000146648 ENSG00000178568 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 EGF EGFR ERBB4 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pEE1HE4_PI3K1_PIP2 Cytoplasm 1.03E-42 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000178568 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 EGF EGFR NRG1 ERBB4 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pE2HE3_PI3K1_PIP2 Cytoplasm 1.84E-15 ENSG00000141736 ENSG00000157168 ENSG00000065361 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 ERBB2 NRG1 ERBB3 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pHE3Ev3_PI3K1_PIP2 Cytoplasm 2.04E-26 ENSG00000157168 ENSG00000065361 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 NRG1 ERBB3 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pE1HE3_PI3K1_PIP2 Cytoplasm 1.77E-14 ENSG00000146648 ENSG00000157168 ENSG00000065361 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 EGFR NRG1 ERBB3 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pHE3E4_PI3K1_PIP2 Cytoplasm 2.16E-26 ENSG00000157168 ENSG00000065361 ENSG00000178568 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 NRG1 ERBB3 ERBB4 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pHE3HE4_PI3K1_PIP2 Cytoplasm 7.95E-42 ENSG00000157168 ENSG00000065361 ENSG00000178568 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 NRG1 ERBB3 ERBB4 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pE2HE4_PI3K1_PIP2 Cytoplasm 1.17E-27 ENSG00000141736 ENSG00000157168 ENSG00000178568 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 ERBB2 NRG1 ERBB4 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pHE4Ev3_PI3K1_PIP2 Cytoplasm 9.20E-39 ENSG00000157168 ENSG00000178568 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 NRG1 ERBB4 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pE1HE4_PI3K1_PIP2 Cytoplasm 8.04E-27 ENSG00000146648 ENSG00000157168 ENSG00000178568 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 EGFR NRG1 ERBB4 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pE3HE4_PI3K1_PIP2 Cytoplasm 9.09E-27 ENSG00000065361 ENSG00000157168 ENSG00000178568 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 ERBB3 NRG1 ERBB4 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pHE4E4_PI3K1_PIP2 Cytoplasm 2.93E-39 ENSG00000157168 ENSG00000178568 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 NRG1 ERBB4 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pHE4HE4_PI3K1_PIP2 Cytoplasm 0.00E+00 ENSG00000157168 ENSG00000178568 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 NRG1 ERBB4 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pHGF_Met_Met_PI3K1_PIP2 Cytoplasm 9.58E-13 ENSG00000019991 ENSG00000105976 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 HGF MET PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pHGF_Met_HGF_Met_PI3K1_PIP2 Cytoplasm 1.67E-26 ENSG00000019991 ENSG00000105976 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 HGF MET PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pPPrPPr_PI3K1_PIP2 Cytoplasm 2.83E-30 ENSG00000100311 ENSG00000134853 ENSG00000113721 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 PDGFB PDGFRA PDGFRB PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pPPrPr_PI3K1_PIP2 Cytoplasm 7.89E-24 ENSG00000100311 ENSG00000134853 ENSG00000113721 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 PDGFB PDGFRA PDGFRB PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pFFrFFr_PI3K1_PIP2 Cytoplasm 3.39E-29 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 FGF1 FGF2 FGFR1 FGFR2 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pFFrFr_PI3K1_PIP2 Cytoplasm 2.24E-15 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 FGF1 FGF2 FGFR1 FGFR2 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pIIrIr_IRS_PI3K1_PIP2 Cytoplasm 1.11E-18 ENSG00000017427 ENSG00000167244 ENSG00000140443 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 IGF1 IGF2 IGF1R PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pINS_Isr_Isr_IRS_PI3K1_PIP2 Cytoplasm 2.03E-16 ENSG00000254647 ENSG00000171105 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 INS INSR PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pIIrIrI_IRS_PI3K1_PIP2 Cytoplasm 1.78E-37 ENSG00000017427 ENSG00000167244 ENSG00000140443 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 IGF1 IGF2 IGF1R PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pINS_Isr_Isr_INS_IRS_PI3K1_PIP2 Cytoplasm 3.20E-27 ENSG00000254647 ENSG00000171105 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 INS INSR PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pEE1E2_PI3K2_PIP Cytoplasm 1.40E-44 ENSG00000138798 ENSG00000146648 ENSG00000141736 ENSG00000011405 EGF EGFR ERBB2 PIK3C2A pEE1Ev3_PI3K2_PIP Cytoplasm 0.00E+00 ENSG00000138798 ENSG00000146648 ENSG00000011405 EGF EGFR PIK3C2A pEE1E1_PI3K2_PIP Cytoplasm 1.75E-44 ENSG00000138798 ENSG00000146648 ENSG00000011405 EGF EGFR PIK3C2A pEE1EE1_PI3K2_PIP Cytoplasm 4.55E-55 ENSG00000138798 ENSG00000146648 ENSG00000011405 EGF EGFR PIK3C2A pEE1E3_PI3K2_PIP Cytoplasm 1.60E-44 ENSG00000138798 ENSG00000146648 ENSG00000065361 ENSG00000011405 EGF EGFR ERBB3 PIK3C2A pEE1HE3_PI3K2_PIP Cytoplasm 8.25E-60 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000065361 ENSG00000011405 EGF EGFR NRG1 ERBB3 PIK3C2A pEE1E4_PI3K2_PIP Cytoplasm 0.00E+00 ENSG00000138798 ENSG00000146648 ENSG00000178568 ENSG00000011405 EGF EGFR ERBB4 PIK3C2A pEE1HE4_PI3K2_PIP Cytoplasm 0.00E+00 ENSG00000138798 ENSG00000146648 ENSG00000157168 ENSG00000178568 ENSG00000011405 EGF EGFR NRG1 ERBB4 PIK3C2A pE2HE3_PI3K2_PIP Cytoplasm 4.40E-32 ENSG00000141736 ENSG00000157168 ENSG00000065361 ENSG00000011405 ERBB2 NRG1 ERBB3 PIK3C2A pHE3Ev3_PI3K2_PIP Cytoplasm 1.62E-54 ENSG00000157168 ENSG00000065361 ENSG00000011405 NRG1 ERBB3 PIK3C2A pE1HE3_PI3K2_PIP Cytoplasm 1.41E-42 ENSG00000146648 ENSG00000157168 ENSG00000065361 ENSG00000011405 EGFR NRG1 ERBB3 PIK3C2A pHE3E4_PI3K2_PIP Cytoplasm 6.86E-54 ENSG00000157168 ENSG00000065361 ENSG00000178568 ENSG00000011405 NRG1 ERBB3 ERBB4 PIK3C2A pHE3HE4_PI3K2_PIP Cytoplasm 0.00E+00 ENSG00000157168 ENSG00000065361 ENSG00000178568 ENSG00000011405 NRG1 ERBB3 ERBB4 PIK3C2A pE2HE4_PI3K2_PIP Cytoplasm 0.00E+00 ENSG00000141736 ENSG00000157168 ENSG00000178568 ENSG00000011405 ERBB2 NRG1 ERBB4 PIK3C2A pHE4Ev3_PI3K2_PIP Cytoplasm 0.00E+00 ENSG00000157168 ENSG00000178568 ENSG00000011405 NRG1 ERBB4 PIK3C2A pE1HE4_PI3K2_PIP Cytoplasm 0.00E+00 ENSG00000146648 ENSG00000157168 ENSG00000178568 ENSG00000011405 EGFR NRG1 ERBB4 PIK3C2A pE3HE4_PI3K2_PIP Cytoplasm 0.00E+00 ENSG00000065361 ENSG00000157168 ENSG00000178568 ENSG00000011405 ERBB3 NRG1 ERBB4 PIK3C2A pHE4E4_PI3K2_PIP Cytoplasm 0.00E+00 ENSG00000157168 ENSG00000178568 ENSG00000011405 NRG1 ERBB4 PIK3C2A pHE4HE4_PI3K2_PIP Cytoplasm 0.00E+00 ENSG00000157168 ENSG00000178568 ENSG00000011405 NRG1 ERBB4 PIK3C2A pHGF_Met_Met_PI3K2_PIP Cytoplasm 6.83E-41 ENSG00000019991 ENSG00000105976 ENSG00000011405 HGF MET PIK3C2A pHGF_Met_HGF_Met_PI3K2_PIP Cytoplasm 7.59E-54 ENSG00000019991 ENSG00000105976 ENSG00000011405 HGF MET PIK3C2A pPPrPPr_PI3K2_PIP Cytoplasm 9.14E-57 ENSG00000100311 ENSG00000134853 ENSG00000113721 ENSG00000011405 PDGFB PDGFRA PDGFRB PIK3C2A pPPrPr_PI3K2_PIP Cytoplasm 9.38E-51 ENSG00000100311 ENSG00000134853 ENSG00000113721 ENSG00000011405 PDGFB PDGFRA PDGFRB PIK3C2A pFFrFFr_PI3K2_PIP Cytoplasm 1.12E-54 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 ENSG00000011405 FGF1 FGF2 FGFR1 FGFR2 PIK3C2A pFFrFr_PI3K2_PIP Cytoplasm 2.48E-42 ENSG00000113578 ENSG00000138685 ENSG00000077782 ENSG00000066468 ENSG00000011405 FGF1 FGF2 FGFR1 FGFR2 PIK3C2A pIIrIr_IRS_PI3K2_PIP Cytoplasm 2.34E-32 ENSG00000017427 ENSG00000167244 ENSG00000140443 ENSG00000011405 IGF1 IGF2 IGF1R PIK3C2A pINS_Isr_Isr_IRS_PI3K2_PIP Cytoplasm 5.61E-31 ENSG00000254647 ENSG00000171105 ENSG00000011405 INS INSR PIK3C2A pIIrIrI_IRS_PI3K2_PIP Cytoplasm 0.00E+00 ENSG00000017427 ENSG00000167244 ENSG00000140443 ENSG00000011405 IGF1 IGF2 IGF1R PIK3C2A pINS_Isr_Isr_INS_IRS_PI3K2_PIP Cytoplasm 0.00E+00 ENSG00000254647 ENSG00000171105 ENSG00000011405 INS INSR PIK3C2A IRS Cytoplasm 9.35E-01 ENSG00000169047 ENSG00000185950 IRS1 IRS2 Sp Cytoplasm 1.81E-02 ENSG00000136158 SPRY2 Cbl Cytoplasm 5.30E+00 ENSG00000110395 CBL G2 Cytoplasm 6.08E+01 ENSG00000177885 GRB2 G2_SOS Cytoplasm 2.78E-01 ENSG00000177885 ENSG00000115904 GRB2 SOS1 G2_pSOS Cytoplasm 2.80E-01 ENSG00000177885 ENSG00000115904 GRB2 SOS1 PLCg Cytoplasm 2.21E+00 ENSG00000124181 ENSG00000197943 PLCG1 PLCG2 PI3KC1 Cytoplasm 2.37E-02 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 PIK3CA PIK3CB PIK3CG PIK3CD PI3KR1 Cytoplasm 8.96E+00 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 PIK3R1 PIK3R2 PIK3R3 PIK3R4 PI3K1 Cytoplasm 2.01E+00 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 pPI3K1 Cytoplasm 3.39E-01 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 PI3K2 Cytoplasm 1.72E+00 ENSG00000011405 PIK3C2A mTORC1 Cytoplasm 2.74E+00 ENSG00000198793 MTOR mTORC1active Cytoplasm 1.86E-01 ENSG00000198793 MTOR PIP Cytoplasm 9.32E-25 PI3P Cytoplasm 3.07E-27 DAG Cytoplasm 8.31E-12 ENSG00000173402 DAG1 GRP Cytoplasm 9.68E+00 ENSG00000172575 ENSG00000152689 RASGRP1 RASGRP3 DAG_GRP Cytoplasm 8.04E-13 ENSG00000173402 ENSG00000172575 ENSG00000152689 DAG1 RASGRP1 RASGRP3 RasT Cytoplasm 2.80E+00 ENSG00000213281 ENSG00000133703 ENSG00000174775 NRAS KRAS HRAS RasD Cytoplasm 1.61E+02 ENSG00000213281 ENSG00000133703 ENSG00000174775 NRAS KRAS HRAS NF1 Cytoplasm 7.81E-01 ENSG00000196712 NF1 pNF1 Cytoplasm 0.00E+00 ENSG00000196712 NF1 pCRaf Cytoplasm 3.27E+00 ENSG00000132155 RAF1 CRaf Cytoplasm 3.24E+00 ENSG00000132155 RAF1 RasT_CRaf Cytoplasm 9.05E-01 ENSG00000213281 ENSG00000133703 ENSG00000174775 ENSG00000132155 NRAS KRAS HRAS RAF1 BRaf Cytoplasm 4.17E-01 ENSG00000157764 BRAF RasT_CRaf_BRaf Cytoplasm 1.05E-01 ENSG00000213281 ENSG00000133703 ENSG00000174775 ENSG00000132155 ENSG00000157764 NRAS KRAS HRAS RAF1 BRAF MEK Cytoplasm 1.25E+02 ENSG00000169032 ENSG00000126934 MAP2K1 MAP2K2 pMEK Cytoplasm 1.63E+01 ENSG00000169032 ENSG00000126934 MAP2K1 MAP2K2 ppMEK Cytoplasm 2.11E+01 ENSG00000169032 ENSG00000126934 MAP2K1 MAP2K2 MKP3 Cytoplasm 1.99E-03 ENSG00000139318 DUSP6 ERKnuc Nucleus 4.07E-01 ENSG00000100030 ENSG00000102882 MAPK1 MAPK3 ppERKnuc Nucleus 7.33E+00 ENSG00000100030 ENSG00000102882 MAPK1 MAPK3 RSK Cytoplasm 6.95E+01 ENSG00000117676 ENSG00000071242 ENSG00000177189 ENSG00000162302 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA4 pRSK Cytoplasm 7.02E-01 ENSG00000117676 ENSG00000071242 ENSG00000177189 ENSG00000162302 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA4 pRSKnuc Nucleus 1.78E+00 ENSG00000117676 ENSG00000071242 ENSG00000177189 ENSG00000162302 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA4 MKP1 Nucleus 2.02E-03 ENSG00000120129 DUSP1 pMKP1 Nucleus 1.59E-02 ENSG00000120129 DUSP1 cFos Nucleus 2.98E+00 ENSG00000170345 FOS pcFos Nucleus 2.47E-01 ENSG00000170345 FOS cJun Nucleus 2.87E+00 ENSG00000177606 JUN pcFos_cJun Nucleus 7.05E-02 ENSG00000170345 ENSG00000177606 FOS JUN cMyc Nucleus 4.54E+01 ENSG00000136997 MYC bCATENINnuc Nucleus 3.55E+01 ENSG00000168036 CTNNB1 bCATENIN Cytoplasm 1.78E+01 ENSG00000168036 CTNNB1 pbCATENIN Cytoplasm 1.80E+02 ENSG00000168036 CTNNB1 IP3 Cytoplasm 1.11E-12 ENSG00000137825 ENSG00000143772 ENSG00000086544 ITPKA ITPKB ITPKC PIP2 Cytoplasm 1.00E+04 PIP3 Cytoplasm 1.61E+00 PTEN Cytoplasm 2.32E+00 ENSG00000171862 PTEN PIP3_AKT Cytoplasm 7.35E-01 ENSG00000142208 ENSG00000105221 AKT1 AKT2 AKT Cytoplasm 4.82E+01 ENSG00000142208 ENSG00000105221 AKT1 AKT2 pAKT Cytoplasm 3.89E-02 ENSG00000142208 ENSG00000105221 AKT1 AKT2 ppAKT Cytoplasm 3.89E-01 ENSG00000142208 ENSG00000105221 AKT1 AKT2 PDK1 Cytoplasm 1.15E+01 ENSG00000140992 PDPK1 PIP3_PDK1 Cytoplasm 1.85E-01 ENSG00000140992 PDPK1 PIP3_pAKT Cytoplasm 6.36E-02 ENSG00000142208 ENSG00000105221 AKT1 AKT2 Rictor Cytoplasm 1.67E-01 ENSG00000164327 RICTOR mTOR Cytoplasm 1.18E+00 ENSG00000198793 MTOR mTORC2 Cytoplasm 1.84E+00 ENSG00000198793 MTOR PIP3_ppAKT Cytoplasm 3.96E-03 ENSG00000142208 ENSG00000105221 AKT1 AKT2 GSK3b Cytoplasm 4.08E+01 ENSG00000082701 GSK3B pGSK3b Cytoplasm 1.44E+00 ENSG00000082701 GSK3B TSC1 Cytoplasm 5.64E-02 ENSG00000165699 TSC1 TSC2 Cytoplasm 3.48E-01 ENSG00000103197 TSC2 pTSC2 Cytoplasm 8.71E-02 ENSG00000103197 TSC2 TSC Cytoplasm 1.97E-01 ENSG00000165699 ENSG00000103197 TSC1 TSC2 PKC Cytoplasm 2.02E+01 ENSG00000154229 ENSG00000166501 ENSG00000126583 ENSG00000163932 PRKCA PRKCB PRKCG PRKCD DAG_PKC Cytoplasm 1.68E-12 ENSG00000173402 ENSG00000154229 ENSG00000166501 ENSG00000126583 ENSG00000163932 DAG1 PRKCA PRKCB PRKCG PRKCD pRKIP Cytoplasm 1.58E-09 ENSG00000089220 PEBP1 RKIP Cytoplasm 1.04E+03 ENSG00000089220 PEBP1 RKIP_CRaf Cytoplasm 0.00E+00 ENSG00000089220 ENSG00000132155 PEBP1 RAF1 ERK Cytoplasm 2.21E+02 ENSG00000100030 ENSG00000102882 MAPK1 MAPK3 pERK Cytoplasm 2.21E+01 ENSG00000100030 ENSG00000102882 MAPK1 MAPK3 ppERK Cytoplasm 1.11E+01 ENSG00000100030 ENSG00000102882 MAPK1 MAPK3 FOXO Cytoplasm 3.01E-01 ENSG00000118689 FOXO3 pFOXO Cytoplasm 5.12E-01 ENSG00000118689 FOXO3 RhebD Cytoplasm 1.05E+02 ENSG00000106615 RHEB RhebT Cytoplasm 0.00E+00 ENSG00000106615 RHEB Raptor Cytoplasm 2.96E-01 ENSG00000141564 RPTOR S6K Cytoplasm 1.84E+01 ENSG00000108443 S6K pS6K Cytoplasm 1.04E+00 ENSG00000108443 S6K EIF4EBP1 Cytoplasm 6.52E-01 ENSG00000187840 EIF4EBP1 pEIF4EBP1 Cytoplasm 1.10E+00 ENSG00000187840 EIF4EBP1 SOS Cytoplasm 5.60E-04 ENSG00000115904 SOS1 G2_SOS_ppERK Cytoplasm 2.81E-03 ENSG00000177885 ENSG00000115904 ENSG00000100030 ENSG00000102882 GRB2 SOS1 MAPK1 MAPK3 CRaf_ppERK Cytoplasm 3.27E-02 ENSG00000132155 ENSG00000100030 ENSG00000102882 RAF1 MAPK1 MAPK3 RasD_DAG_GRP Cytoplasm 1.18E-13 ENSG00000213281 ENSG00000133703 ENSG00000174775 ENSG00000172575 ENSG00000152689 NRAS KRAS HRAS RASGRP1 RASGRP3 RasT_NF1 Cytoplasm 3.65E-03 ENSG00000213281 ENSG00000133703 ENSG00000174775 ENSG00000196712 NRAS KRAS HRAS NF1 NF1_ppERK Cytoplasm 0.00E+00 ENSG00000196712 ENSG00000102882 ENSG00000100030 ENSG00000069956 ENSG00000141639 ENSG00000166484 ENSG00000188130 ENSG00000181085 NF1 MAPK3 MAPK1 MAPK6 MAPK4 MAPK7 MAPK12 MAPK15 MEK_RasT_CRaf_BRaf Cytoplasm 2.20E-01 ENSG00000169032 ENSG00000126934 ENSG00000213281 ENSG00000133703 ENSG00000174775 ENSG00000196712 ENSG00000132155 ENSG00000157764 MAP2K1 MAP2K2 NRAS KRAS HRAS NF1 RAF1 BRAF pMEK_RasT_CRaf_BRaf Cytoplasm 2.86E-02 ENSG00000169032 ENSG00000126934 ENSG00000213281 ENSG00000133703 ENSG00000174775 ENSG00000196712 ENSG00000132155 ENSG00000157764 MAP2K1 MAP2K2 NRAS KRAS HRAS NF1 RAF1 BRAF ERK_ppMEK Cytoplasm 2.33E+00 ENSG00000100030 ENSG00000102882 ENSG00000169032 ENSG00000126934 MAPK1 MAPK3 MAP2K1 MAP2K2 pERK_ppMEK Cytoplasm 2.33E-01 ENSG00000100030 ENSG00000102882 ENSG00000169032 ENSG00000126934 MAPK1 MAPK3 MAP2K1 MAP2K2 RSK_ppERK Cytoplasm 7.02E-01 ENSG00000117676 ENSG00000071242 ENSG00000177189 ENSG00000162302 ENSG00000100030 ENSG00000102882 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA4 MAPK1 MAPK3 pRSKnuc_MKP1 Nucleus 3.27E-06 ENSG00000117676 ENSG00000071242 ENSG00000177189 ENSG00000162302 ENSG00000120129 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA4 DUSP1 ppERKnuc_MKP1 Nucleus 1.34E-05 ENSG00000100030 ENSG00000102882 ENSG00000120129 MAPK1 MAPK3 DUSP1 cFos_pRSKnuc Nucleus 4.83E-03 ENSG00000170345 ENSG00000117676 ENSG00000071242 ENSG00000177189 ENSG00000162302 FOS RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA4 cFos_ppERKnuc Nucleus 1.99E-02 ENSG00000170345 ENSG00000100030 ENSG00000102882 FOS MAPK1 MAPK3 RKIP_DAG_PKC Cytoplasm 1.58E-12 ENSG00000089220 ENSG00000173402 ENSG00000154229 ENSG00000166501 ENSG00000126583 ENSG00000163932 PEBP1 DAG1 PRKCA PRKCB PRKCG PRKCD PIP3_PTEN Cytoplasm 3.38E-03 ENSG00000171862 PTEN PIP3_AKT_PIP3_PDK1 Cytoplasm 4.53E-04 ENSG00000142208 ENSG00000105221 ENSG00000140992 AKT1 AKT2 PDPK1 PIP3_pAKT_mTORC2 Cytoplasm 3.90E-04 ENSG00000142208 ENSG00000105221 ENSG00000198793 AKT1 AKT2 MTOR GSK3b_ppAKT Cytoplasm 1.44E-02 ENSG00000082701 ENSG00000142208 ENSG00000105221 GSK3B AKT1 AKT2 TSC2_ppAKT Cytoplasm 6.78E-04 ENSG00000103197 ENSG00000142208 ENSG00000105221 TSC2 AKT1 AKT2 TSC2_ppERK Cytoplasm 1.94E-03 ENSG00000103197 ENSG00000100030 ENSG00000102882 TSC2 MAPK1 MAPK3 RhebT_TSC Cytoplasm 0.00E+00 ENSG00000106615 ENSG00000165699 ENSG00000103197 RHEB TSC1 TSC2 EIF4EBP1_mTORC1active Cytoplasm 1.10E-03 ENSG00000187840 ENSG00000198793 EIF4EBP1 MTOR S6K_mTORC1active Cytoplasm 3.12E-03 ENSG00000108443 ENSG00000198793 S6K MTOR FOXO_ppAKT Cytoplasm 5.33E-04 ENSG00000118689 ENSG00000142208 ENSG00000105221 FOXO3 AKT1 AKT2 PI3K1_mTORC1active Cytoplasm 3.40E-04 ENSG00000121879 ENSG00000051382 ENSG00000105851 ENSG00000171608 ENSG00000145675 ENSG00000105647 ENSG00000117461 ENSG00000196455 ENSG00000198793 PIK3CA PIK3CB PIK3CG PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 MTOR pERK_MKP3 Cytoplasm 3.98E-05 ENSG00000100030 ENSG00000102882 ENSG00000139318 MAPK1 MAPK3 DUSP6 ppERK_MKP3 Cytoplasm 0.00E+00 ENSG00000100030 ENSG00000102882 ENSG00000139318 MAPK1 MAPK3 DUSP6 ppERKnuc_pMKP1 Cytoplasm 1.06E-04 ENSG00000100030 ENSG00000102882 ENSG00000120129 MAPK1 MAPK3 DUSP1 RasT_BRaf Cytoplasm 1.16E-01 ENSG00000213281 ENSG00000133703 ENSG00000174775 ENSG00000157764 NRAS KRAS HRAS BRAF RasT_BRaf_BRaf Cytoplasm 1.35E-03 ENSG00000213281 ENSG00000133703 ENSG00000174775 ENSG00000157764 NRAS KRAS HRAS BRAF MEK_RasT_BRaf_BRaf Cytoplasm 1.54E-03 ENSG00000169032 ENSG00000126934 ENSG00000213281 ENSG00000133703 ENSG00000174775 ENSG00000157764 MAP2K1 MAP2K2 NRAS KRAS HRAS BRAF pMEK_RasT_BRaf_BRaf Cytoplasm 2.00E-04 ENSG00000169032 ENSG00000126934 ENSG00000213281 ENSG00000133703 ENSG00000174775 ENSG00000157764 MAP2K1 MAP2K2 NRAS KRAS HRAS BRAF EIF4E Cytoplasm 2.36E+02 ENSG00000151247 EIF4E EIF4EBP1_EIF4E Cytoplasm 1.53E+01 ENSG00000187840 ENSG00000151247 EIF4EBP1 EIF4E RasT_CRaf_CRaf Cytoplasm 8.19E-02 ENSG00000213281 ENSG00000133703 ENSG00000174775 ENSG00000132155 NRAS KRAS HRAS RAF1 MEK_RasT_CRaf_CRaf Cytoplasm 5.13E-01 ENSG00000169032 ENSG00000126934 ENSG00000213281 ENSG00000133703 ENSG00000174775 ENSG00000132155 MAP2K1 MAP2K2 NRAS KRAS HRAS RAF1 pMEK_RasT_CRaf_CRaf Cytoplasm 6.66E-02 ENSG00000169032 ENSG00000126934 ENSG00000213281 ENSG00000133703 ENSG00000174775 ENSG00000132155 MAP2K1 MAP2K2 NRAS KRAS HRAS RAF1 FOXOnuc Nucleus 9.03E+00 ENSG00000118689 FOXO3 MEKi Cytoplasm 0.00E+00 MEKi_ppMEK Cytoplasm 0.00E+00 MEK1 MEK2 AKTi Cytoplasm 0.00E+00 AKTi_AKT Cytoplasm 0.00E+00 AKT1 AKT2 mT Cytoplasm 3.77E+01 EIF4E_mT Cytoplasm 8.88E+01 ENSG00000151247 EIF4E m_TP53 Cytoplasm 2.53E-03 ENSG00000141510 TP53 m_MDM2 Cytoplasm 1.58E-02 ENSG00000135679 MDM2 m_PPM1D Cytoplasm 6.32E-04 ENSG00000170836 PPM1D m_ATM Cytoplasm 9.49E-04 ENSG00000149311 ATM m_ATR Cytoplasm 6.32E-04 ENSG00000175054 ATR m_RB1 Cytoplasm 5.38E-03 ENSG00000139687 RB1 m_E2F1 Cytoplasm 5.38E-03 ENSG00000101412 E2F1 m_E2F2 Cytoplasm 5.38E-03 ENSG00000007968 E2F2 m_E2F3 Cytoplasm 5.38E-03 ENSG00000112242 E2F3 m_CCND1 Cytoplasm 1.90E-03 ENSG00000110092 CCND1 m_CCND2 Cytoplasm 3.16E-04 ENSG00000118971 CCND2 m_CCND3 Cytoplasm 6.32E-04 ENSG00000112576 CCND3 m_CCNE1 Cytoplasm 5.38E-03 ENSG00000105173 CCNE1 m_CCNE2 Cytoplasm 5.38E-03 ENSG00000175305 CCNE2 m_SKP2 Cytoplasm 5.38E-03 ENSG00000145604 SKP2 m_CDC25A Cytoplasm 5.38E-03 ENSG00000164045 CDC25A m_CDC25B Cytoplasm 5.38E-03 ENSG00000101224 CDC25B m_CDC25C Cytoplasm 5.38E-03 ENSG00000158402 CDC25C m_CCNA2 Cytoplasm 5.38E-03 ENSG00000145386 CCNA2 m_CDKN1B Cytoplasm 5.38E-03 ENSG00000111276 CDKN1B m_CDH1 Cytoplasm 5.38E-03 ENSG00000039068 CDH1 m_CCNB1 Cytoplasm 5.38E-03 ENSG00000134057 CCNB1 m_CDC20 Cytoplasm 5.38E-03 ENSG00000117399 CDC20 m_WEE1 Cytoplasm 5.38E-03 ENSG00000166483 WEE1 m_CHEK1 Cytoplasm 5.38E-03 ENSG00000149554 CHEK1 m_CDKN1A Cytoplasm 3.79E-03 ENSG00000124762 CDKN1A m_CDK1 Cytoplasm 1.39E-02 ENSG00000170312 CDK1 m_CDK2 Cytoplasm 6.32E-04 ENSG00000123374 CDK2 m_CDK4 Cytoplasm 3.48E-03 ENSG00000135446 CDK4 m_CDK6 Cytoplasm 2.21E-03 ENSG00000124762 CDK6 m_TNFSF10 Cytoplasm 0.00E+00 ENSG00000121858 TNFSF10 m_TNFRSF10A Cytoplasm 3.16E-04 ENSG00000104689 TNFRSF10A m_TNFRSF10B Cytoplasm 4.11E-03 ENSG00000120889 TNFRSF10B m_CFLAR Cytoplasm 3.16E-03 ENSG00000003402 CFLAR m_CASP8 Cytoplasm 2.53E-03 ENSG00000064012 CASP8 m_CASP10 Cytoplasm 1.58E-03 ENSG00000003400 CASP10 m_BFAR Cytoplasm 1.14E-02 ENSG00000103429 BFAR m_CASP3 Cytoplasm 4.11E-03 ENSG00000164305 CASP3 m_CASP7 Cytoplasm 7.27E-03 ENSG00000165806 CASP7 m_CASP6 Cytoplasm 8.54E-03 ENSG00000138794 CASP6 m_XIAP Cytoplasm 1.58E-03 ENSG00000101966 XIAP m_PARP1 Cytoplasm 6.64E-03 ENSG00000143799 PARP1 m_BID Cytoplasm 4.74E-03 ENSG00000015475 BID m_BCL2 Cytoplasm 0.00E+00 ENSG00000171791 BCL2 m_BCL2L1 Cytoplasm 9.49E-04 ENSG00000171552 BCL2L1 m_MCL1 Cytoplasm 6.64E-03 ENSG00000143384 MCL1 m_BAX Cytoplasm 9.49E-04 ENSG00000087088 BAX m_CYCS Cytoplasm 2.91E-02 ENSG00000172115 CYCS m_DIABLO Cytoplasm 2.85E-03 ENSG00000184047 DIABLO m_APAF1 Cytoplasm 6.32E-04 ENSG00000120868 APAF1 m_CASP9 Cytoplasm 6.32E-04 ENSG00000132906 CASP9 m_BAD Cytoplasm 4.11E-03 ENSG00000002330 BAD m_BBC3 Cytoplasm 3.16E-04 ENSG00000105327 BBC3 m_PMAIP1 Cytoplasm 1.26E-03 ENSG00000141682 PMAIP1 m_BCL2L11 Cytoplasm 9.49E-04 ENSG00000153094 BCL2L11 m_EGF Cytoplasm 0.00E+00 ENSG00000138798 EGF m_NRG1 Cytoplasm 0.00E+00 ENSG00000157168 NRG1 m_EGFR Cytoplasm 2.53E-03 ENSG00000146648 EGFR m_ERBB2 Cytoplasm 1.26E-03 ENSG00000141736 ERBB2 m_ERBB3 Cytoplasm 5.38E-03 ENSG00000065361 ERBB3 m_ERBB4 Cytoplasm 0.00E+00 ENSG00000178568 ERBB4 m_EGFRvIII Cytoplasm 0.00E+00 ENSG00000146648 EGFRvIII m_MET Cytoplasm 5.69E-03 ENSG00000105976 MET m_HGF Cytoplasm 0.00E+00 ENSG00000019991 HGF m_PDGFRA Cytoplasm 3.16E-04 ENSG00000134853 PDGFRA m_PDGFRB Cytoplasm 3.16E-04 ENSG00000113721 PDGFRB m_PDGFB Cytoplasm 0.00E+00 ENSG00000100311 PDGFB m_SPRY2 Cytoplasm 6.32E-04 ENSG00000136158 SPRY2 m_CBL Cytoplasm 9.49E-04 ENSG00000110395 CBL m_GRB2 Cytoplasm 1.58E-03 ENSG00000177885 GRB2 m_PLCG1 Cytoplasm 3.16E-04 ENSG00000124181 PLCG1 m_PLCG2 Cytoplasm 3.16E-04 ENSG00000197943 PLCG2 m_PIK3CA Cytoplasm 6.32E-04 ENSG00000121879 PIK3CA m_PIK3CB Cytoplasm 6.32E-04 ENSG00000051382 PIK3CB m_PIK3CG Cytoplasm 0.00E+00 ENSG00000105851 PIK3CG m_PIK3CD Cytoplasm 0.00E+00 ENSG00000171608 PIK3CD m_PIK3R1 Cytoplasm 6.32E-04 ENSG00000145675 PIK3R1 m_PIK3R2 Cytoplasm 3.16E-04 ENSG00000105647 PIK3R2 m_PIK3R3 Cytoplasm 2.85E-03 ENSG00000117461 PIK3R3 m_PIK3R4 Cytoplasm 3.16E-04 ENSG00000196455 PIK3R4 m_PIK3C2A Cytoplasm 1.58E-03 ENSG00000011405 PIK3C2A m_RASGRP1 Cytoplasm 0.00E+00 ENSG00000172575 RASGRP1 m_RASGRP3 Cytoplasm 3.16E-04 ENSG00000152689 RASGRP3 m_NRAS Cytoplasm 4.43E-03 ENSG00000213281 NRAS m_KRAS Cytoplasm 2.53E-03 ENSG00000133703 KRAS m_HRAS Cytoplasm 9.49E-04 ENSG00000174775 HRAS m_NF1 Cytoplasm 1.26E-03 ENSG00000196712 NF1 m_RAF1 Cytoplasm 1.90E-03 ENSG00000132155 RAF1 m_BRAF Cytoplasm 3.16E-04 ENSG00000157764 BRAF m_MAP2K1 Cytoplasm 6.32E-04 ENSG00000169032 MAP2K1 m_MAP2K2 Cytoplasm 9.49E-04 ENSG00000126934 MAP2K2 m_DUSP6 Cytoplasm 3.16E-04 ENSG00000139318 DUSP6 m_RPS6KA1 Cytoplasm 3.16E-04 ENSG00000117676 RPS6KA1 m_RPS6KA2 Cytoplasm 6.32E-04 ENSG00000071242 RPS6KA2 m_RPS6KA3 Cytoplasm 1.26E-03 ENSG00000177189 RPS6KA3 m_RPS6KA4 Cytoplasm 3.16E-04 ENSG00000162302 RPS6KA4 m_DUSP1 Cytoplasm 9.49E-04 ENSG00000120129 DUSP1 m_FOS Cytoplasm 9.49E-04 ENSG00000170345 FOS m_JUN Cytoplasm 2.21E-03 ENSG00000177606 JUN m_MYC Cytoplasm 6.32E-04 ENSG00000136997 MYC m_CTNNB1 Cytoplasm 1.04E-02 ENSG00000168036 CTNNB1 m_PTEN Cytoplasm 7.27E-03 ENSG00000171862 PTEN m_AKT1 Cytoplasm 3.16E-04 ENSG00000142208 AKT1 m_AKT2 Cytoplasm 9.49E-04 ENSG00000105221 AKT2 m_PDPK1 Cytoplasm 9.49E-04 ENSG00000140992 PDPK1 m_RICTOR Cytoplasm 1.26E-03 ENSG00000164327 RICTOR m_MTOR Cytoplasm 3.16E-04 ENSG00000198793 MTOR m_GSK3B Cytoplasm 9.49E-04 ENSG00000082701 GSK3B m_TSC1 Cytoplasm 1.26E-03 ENSG00000165699 TSC1 m_TSC2 Cytoplasm 3.16E-04 ENSG00000103197 TSC2 m_PRKCA Cytoplasm 6.32E-04 ENSG00000154229 PRKCA m_PRKCB Cytoplasm 3.16E-04 ENSG00000166501 PRKCB m_PRKCG Cytoplasm 0.00E+00 ENSG00000126583 PRKCG m_PRKCD Cytoplasm 9.49E-04 ENSG00000163932 PRKCD m_PEBP1 Cytoplasm 1.17E-02 ENSG00000089220 PEBP1 m_MAPK1 Cytoplasm 1.90E-03 ENSG00000100030 MAPK1 m_MAPK3 Cytoplasm 6.32E-04 ENSG00000102882 MAPK3 m_FOXO3 Cytoplasm 1.26E-03 ENSG00000118689 FOXO3 m_RHEB Cytoplasm 9.80E-03 ENSG00000106615 RHEB m_RPTOR Cytoplasm 3.16E-04 ENSG00000141564 RPTOR m_RPS6KB1 Cytoplasm 9.49E-04 ENSG00000108443 RPS6KB1 m_RPS6KB2 Cytoplasm 6.32E-04 ENSG00000175634 RPS6KB2 m_EIF4EBP1 Cytoplasm 1.20E-02 ENSG00000187840 EIF4EBP1 m_SOS1 Cytoplasm 9.49E-04 ENSG00000115904 SOS1 m_CDKN2A Cytoplasm 0.00E+00 ENSG00000147889 CDKN2A m_MDM4 Cytoplasm 2.21E-03 ENSG00000198625 MDM4 m_FGFR1 Cytoplasm 3.16E-04 ENSG00000077782 FGFR1 m_FGFR2 Cytoplasm 6.32E-04 ENSG00000066468 FGFR2 m_FGF1 Cytoplasm 0.00E+00 ENSG00000113578 FGF1 m_FGF2 Cytoplasm 0.00E+00 ENSG00000138685 FGF2 m_EIF4E Cytoplasm 1.20E-02 ENSG00000151247 EIF4E m_IRS1 Cytoplasm 9.49E-04 ENSG00000169047 IRS1 m_IRS2 Cytoplasm 6.32E-04 ENSG00000185950 IRS2 m_IGF1 Cytoplasm 0.00E+00 ENSG00000017427 IGF1 m_IGF2 Cytoplasm 0.00E+00 ENSG00000167244 IGF2 m_IGF1R Cytoplasm 9.49E-04 ENSG00000140443 IGF1R m_MSH6 Cytoplasm 1.58E-03 ENSG00000116062 MSH6 m_BRCA2 Cytoplasm 6.32E-04 ENSG00000139618 BRCA2 m_MGMT Cytoplasm 1.58E-03 ENSG00000170430 MGMT m_INSR Cytoplasm 1.90E-03 ENSG00000171105 INSR m_INS Cytoplasm 0.00E+00 ENSG00000254647 INS