gene_id	expression_36h	expression_24h	log2FC(36h/24h)	pval	padj	regulate	significant	fpkm_36P1	fpkm_36P2	fpkm_36P3	fpkm_24P1	fpkm_24P2	fpkm_24P3	chr	start	end	strand	gene_name	gene_biotype	GO_biological_process	GO_cellular_component	GO_molecular_function	KEGG_genes	KEGG_pathways	gene_length	NR_tophit_name	NR_tophit_description	Swissprot_tophit_name	Swissprot_tophit_description	String_tophit_name	String_tophit_description	COG	KOG	NOG	Pfam
ENSGALG00000000044	2.401794164	0.830103148	1.521468406	3.70E-07	1.24E-06	up	yes	1.886471091	3.386362732	1.932548669	0.893108032	0.810410734	0.786790679	14	13962836	13964455	+	WFIKKN1	protein_coding	GO:0001501|skeletal system development; GO:0030512|negative regulation of transforming growth factor beta receptor signaling pathway; GO:0032091|negative regulation of protein binding; GO:0043392|negative regulation of DNA binding; GO:0048747|muscle fiber development; GO:0060021|roof of mouth development	GO:0005576|extracellular region	GO:0004867|serine-type endopeptidase inhibitor activity; GO:0008191|metalloendopeptidase inhibitor activity; GO:0048019|receptor antagonist activity; GO:0050431|transforming growth factor beta binding	--	--	1620	XP_025011059.1	"XP_025011059.1 WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 [Gallus gallus]"	sp|Q96NZ8|WFKN1_HUMAN	"sp|Q96NZ8|WFKN1_HUMAN WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 OS=Homo sapiens GN=WFIKKN1 PE=1 SV=1"	9031.ENSGALP00000000058	"WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1"	_	KOG4597	_	PF00014.20|Kunitz_BPTI|Kunitz/Bovine pancreatic trypsin inhibitor domain|ENSGALT00000000059|m.10023:294-344;PF00014.20|Kunitz_BPTI|Kunitz/Bovine pancreatic trypsin inhibitor domain|ENSGALT00000000059|m.10023:351-402;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000000059|m.10023:183-272;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000000059|m.10023:177-259;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000000059|m.10023:184-271;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000000059|m.10023:188-261;PF01759.18|NTR|UNC-6/NTR/C345C module|ENSGALT00000000059|m.10023:423-524;PF07648.12|Kazal_2|Kazal-type serine protease inhibitor domain|ENSGALT00000000059|m.10023:111-142
ENSGALG00000000048	9.393016216	3.688829019	1.346054994	1.90E-23	2.18E-22	up	yes	9.261570103	9.073263564	9.844214983	3.159655576	4.45280623	3.45402525	25	482603	488101	+	ENSGALG00000000048	protein_coding	GO:0006810|transport; GO:0006879|cellular iron ion homeostasis; GO:0008286|insulin receptor signaling pathway; GO:0016241|regulation of macroautophagy; GO:0033572|transferrin transport; GO:0034220|ion transmembrane transport; GO:0036295|cellular response to increased oxygen levels; GO:0046034|ATP metabolic process; GO:0090383|phagosome acidification; GO:1902600|proton transmembrane transport	"GO:0005739|mitochondrion; GO:0005765|lysosomal membrane; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0005902|microvillus; GO:0016324|apical plasma membrane; GO:0016469|proton-transporting two-sector ATPase complex; GO:0033180|proton-transporting V-type ATPase, V1 domain; GO:0043209|myelin sheath; GO:0070062|extracellular exosome"	"GO:0005524|ATP binding; GO:0046961|proton-transporting ATPase activity, rotational mechanism"	"ko:K02145|ATPeV1A,ATP6A"	ko00190|Oxidative phosphorylation; ko01100|Metabolic pathways; ko04145|Phagosome; ko04150|mTOR signaling pathway; ko04721|Synaptic vesicle cycle; ko04966|Collecting duct acid secretion; ko05110|Vibrio cholerae infection; ko05120|Epithelial cell signaling in Helicobacter pylori infection; ko05323|Rheumatoid arthritis	2516	XP_004948457.1	XP_004948457.1 V-type proton ATPase catalytic subunit A-like [Gallus gallus]	sp|P38606|VATA_HUMAN	sp|P38606|VATA_HUMAN V-type proton ATPase catalytic subunit A OS=Homo sapiens GN=ATP6V1A PE=1 SV=2	_	_	_	_	_	"PF00006.22|ATP-synt_ab|ATP synthase alpha/beta family, nucleotide-binding domain|ENSGALT00000105435|m.6634:202-427;PF16886.2|ATP-synt_ab_Xtn|ATPsynthase alpha/beta subunit N-term extension|ENSGALT00000105435|m.6634:113-193"
ENSGALG00000000104	1.39554277	3.135773394	-1.162287396	2.68E-07	9.10E-07	down	yes	1.015731838	1.526707705	1.644188765	3.409936289	2.982757854	3.01462604	26	1089542	1098705	-	CRY4	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006094|gluconeogenesis; GO:0006351|transcription, DNA-templated; GO:0006975|DNA damage induced protein phosphorylation; GO:0018298|protein-chromophore linkage; GO:0031397|negative regulation of protein ubiquitination; GO:0032922|circadian regulation of gene expression; GO:0033762|response to glucagon; GO:0042593|glucose homeostasis; GO:0042752|regulation of circadian rhythm; GO:0042754|negative regulation of circadian rhythm; GO:0043153|entrainment of circadian clock by photoperiod; GO:0045744|negative regulation of G protein-coupled receptor signaling pathway; GO:0045892|negative regulation of transcription, DNA-templated; GO:2000001|regulation of DNA damage checkpoint; GO:2000323|negative regulation of glucocorticoid receptor signaling pathway"	GO:0005634|nucleus; GO:0005737|cytoplasm	GO:0000166|nucleotide binding; GO:0001047|core promoter binding; GO:0009881|photoreceptor activity	ko:K02295|CRY	ko04710|Circadian rhythm	2075	NP_001034685.1	NP_001034685.1 cryptochrome 4 [Gallus gallus]	sp|Q8WP19|CRY1_MACFA	sp|Q8WP19|CRY1_MACFA Cryptochrome-1 OS=Macaca fascicularis GN=CRY1 PE=2 SV=1	9031.ENSGALP00000039876	cryptochrome 4 	COG0415	KOG0133	_	PF03441.11|FAD_binding_7|FAD binding domain of DNA photolyase|ENSGALT00000000143|m.7674:286-484;PF00875.15|DNA_photolyase|DNA photolyase|ENSGALT00000000143|m.7674:6-158
ENSGALG00000000234	1.554451346	4.510259096	-1.530748677	3.87E-17	3.01E-16	down	yes	1.414525882	1.616705149	1.632123006	3.873166428	5.051412458	4.6061984	Z	46272436	46396602	+	EPB41L4A	protein_coding	GO:0031032|actomyosin structure organization	GO:0005737|cytoplasm; GO:0005856|cytoskeleton	GO:0005200|structural constituent of cytoskeleton; GO:0008092|cytoskeletal protein binding	--	--	2527	XP_413976.3	XP_413976.3 band 4.1-like protein 4A isoform X2 [Gallus gallus]	sp|Q9HCS5|E41LA_HUMAN	sp|Q9HCS5|E41LA_HUMAN Band 4.1-like protein 4A OS=Homo sapiens GN=EPB41L4A PE=1 SV=2	9031.ENSGALP00000000312	erythrocyte membrane protein band 4.1 like 4A	_	KOG3530	_	PF09379.7|FERM_N|FERM N-terminal domain|ENSGALT00000000313|m.11488:177-243;PF09380.7|FERM_C|FERM C-terminal PH-like domain|ENSGALT00000000313|m.11488:378-461;PF00373.15|FERM_M|FERM central domain|ENSGALT00000000313|m.11488:267-373;PF08736.8|FA|FERM adjacent (FA)|ENSGALT00000000313|m.11488:473-517
ENSGALG00000000241	10.30075483	4.005490917	1.360501672	2.75E-44	8.22E-43	up	yes	10.77098529	9.885707651	10.24557155	3.617841248	4.390157037	4.008474467	Z	46594962	46603606	+	STARD4	protein_coding	GO:0010873|positive regulation of cholesterol esterification; GO:0010879|cholesterol transport involved in cholesterol storage; GO:0032367|intracellular cholesterol transport; GO:0070508|cholesterol import; GO:0070859|positive regulation of bile acid biosynthetic process	GO:0005739|mitochondrion; GO:0031410|cytoplasmic vesicle	GO:0015485|cholesterol binding; GO:0120020|cholesterol transfer activity	--	--	4759	NP_001073210.1	NP_001073210.1 stAR-related lipid transfer protein 4 [Gallus gallus]	sp|Q96DR4|STAR4_HUMAN	sp|Q96DR4|STAR4_HUMAN StAR-related lipid transfer protein 4 OS=Homo sapiens GN=STARD4 PE=2 SV=1	9031.ENSGALP00000000319	Putative uncharacterized protein 	_	KOG3845	_	PF01852.16|START|START domain|ENSGALT00000000320|m.11492:55-237
ENSGALG00000000293	9.050536326	3.631137077	1.315207397	3.12E-43	8.89E-42	up	yes	9.42733301	8.32000768	9.404268287	3.51342913	3.7585095	3.621472601	27	4101688	4112295	+	ENSGALG00000000293	protein_coding	GO:0052548|regulation of endopeptidase activity	GO:0005615|extracellular space; GO:0070062|extracellular exosome	GO:0004867|serine-type endopeptidase inhibitor activity; GO:0030414|peptidase inhibitor activity	--	--	4857	XP_015154891.1	XP_015154891.1 alpha-2-macroglobulin-like protein 1 [Gallus gallus]	sp|A8K2U0|A2ML1_HUMAN	sp|A8K2U0|A2ML1_HUMAN Alpha-2-macroglobulin-like protein 1 OS=Homo sapiens GN=A2ML1 PE=1 SV=3	9031.ENSGALP00000000383	annotation not avaliable	COG2373	KOG1366	_	PF07678.11|A2M_comp|A-macroglobulin complement component|ENSGALT00000000384|m.8778:1021-1262;PF00207.19|A2M|Alpha-2-macroglobulin family|ENSGALT00000000384|m.8778:752-841;PF07677.11|A2M_recep|A-macroglobulin receptor|ENSGALT00000000384|m.8778:1371-1458;PF07703.11|A2M_N_2|Alpha-2-macroglobulin family N-terminal region|ENSGALT00000000384|m.8778:450-598;PF01835.16|A2M_N|MG2 domain|ENSGALT00000000384|m.8778:127-211;PF10569.6|Thiol-ester_cl|Alpha-macro-globulin thiol-ester bond-forming region|ENSGALT00000000384|m.8778:971-1000;PF05326.8|SVA|Seminal vesicle autoantigen (SVA)|ENSGALT00000000384|m.8778:803-898
ENSGALG00000000400	0.509093127	0.206176192	1.263785741	5.92E-05	0.000149976	up	yes	0.563440625	0.599016976	0.364821781	0.176614309	0.204268815	0.237645452	26	1366688	1389976	+	KCNC4	protein_coding	GO:0006813|potassium ion transport; GO:0007268|chemical synaptic transmission; GO:0046928|regulation of neurotransmitter secretion; GO:0051260|protein homooligomerization	GO:0005886|plasma membrane; GO:0008076|voltage-gated potassium channel complex; GO:0016021|integral component of membrane; GO:0031594|neuromuscular junction; GO:0043679|axon terminus	GO:0005249|voltage-gated potassium channel activity; GO:0005267|potassium channel activity	ko:K04890|KCNC4	--	4960	XP_013055848.1	XP_013055848.1 PREDICTED: potassium voltage-gated channel subfamily C member 4 isoform X1 [Anser cygnoides domesticus]	sp|Q03721|KCNC4_HUMAN	sp|Q03721|KCNC4_HUMAN Potassium voltage-gated channel subfamily C member 4 OS=Homo sapiens GN=KCNC4 PE=1 SV=2	_	_	_	_	_	PF00520.28|Ion_trans|Ion transport protein|ENSGALT00000061883|m.7828:217-471;PF02214.19|BTB_2|BTB/POZ domain|ENSGALT00000061883|m.7828:38-132;PF11404.5|Potassium_chann|Potassium voltage-gated channel|ENSGALT00000061883|m.7828:1-29;PF07885.13|Ion_trans_2|Ion channel|ENSGALT00000061883|m.7828:380-464
ENSGALG00000000458	0.1741762	0.500734562	-1.471487051	0.001390167	0.002868407	down	yes	0.147428901	0.172951997	0.202147702	0.59891523	0.244891884	0.658396574	28	710915	722418	+	TMPRSS9	protein_coding	GO:0006508|proteolysis; GO:0031639|plasminogen activation	GO:0005887|integral component of plasma membrane	GO:0004252|serine-type endopeptidase activity; GO:0008236|serine-type peptidase activity	ko:K09640|TMPRSS9	--	3412	XP_004948709.2	XP_004948709.2 transmembrane protease serine 9 isoform X1 [Gallus gallus]	sp|P69526|TMPS9_RAT	sp|P69526|TMPS9_RAT Transmembrane protease serine 9 OS=Rattus norvegicus GN=Tmprss9 PE=3 SV=1	_	_	_	_	_	PF00089.23|Trypsin|Trypsin|ENSGALT00000062240|m.9547:238-466;PF00089.23|Trypsin|Trypsin|ENSGALT00000062240|m.9547:539-766;PF00089.23|Trypsin|Trypsin|ENSGALT00000062240|m.9547:890-1068;PF09342.8|DUF1986|Domain of unknown function (DUF1986)|ENSGALT00000062240|m.9547:901-1014;PF00057.15|Ldl_recept_a|Low-density lipoprotein receptor domain class A|ENSGALT00000062240|m.9547:188-224;PF01390.17|SEA|SEA domain|ENSGALT00000062240|m.9547:58-149
ENSGALG00000000461	0.437496852	0.204610917	1.060154064	0.009622628	0.017073452	up	yes	0.328529572	0.685576324	0.298384659	0.261410353	0.154919215	0.197503183	27	4832151	4845337	+	ENSGALG00000000461	protein_coding	GO:0001649|osteoblast differentiation; GO:0006897|endocytosis; GO:0030574|collagen catabolic process	GO:0005887|integral component of plasma membrane; GO:0005925|focal adhesion; GO:0016020|membrane	GO:0004888|transmembrane signaling receptor activity; GO:0005518|collagen binding; GO:0030246|carbohydrate binding	"ko:K06560|MRC,CD206,CD280"	ko04145|Phagosome; ko05152|Tuberculosis	4170	XP_015154875.1	XP_015154875.1 C-type mannose receptor 2 [Gallus gallus]	sp|Q9UBG0|MRC2_HUMAN	sp|Q9UBG0|MRC2_HUMAN C-type mannose receptor 2 OS=Homo sapiens GN=MRC2 PE=1 SV=2	_	_	_	_	_	PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000000627|m.8802:165-270;PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000000627|m.8802:308-415;PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000000627|m.8802:449-554;PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000000627|m.8802:602-718;PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000000627|m.8802:753-861;PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000000627|m.8802:906-1019;PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000000627|m.8802:1053-1154;PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000000627|m.8802:1199-1304;PF00040.16|fn2|Fibronectin type II domain|ENSGALT00000000627|m.8802:96-137
ENSGALG00000000545	1.303199993	3.299524562	-1.33353733	4.84E-09	1.96E-08	down	yes	1.321915528	1.59837866	0.989305792	2.730436999	3.733066547	3.43507014	26	1725734	1730462	-	REN	protein_coding	GO:0001823|mesonephros development; GO:0002003|angiotensin maturation; GO:0002018|renin-angiotensin regulation of aldosterone production; GO:0008584|male gonad development; GO:0009755|hormone-mediated signaling pathway; GO:0042756|drinking behavior; GO:0043408|regulation of MAPK cascade; GO:0048469|cell maturation	GO:0005615|extracellular space; GO:0005622|intracellular; GO:0016020|membrane; GO:0045177|apical part of cell	GO:0004190|aspartic-type endopeptidase activity; GO:0005102|signaling receptor binding	ko:K01380|REN	ko04614|Renin-angiotensin system; ko04924|Renin secretion	2272	XP_004934957.3	XP_004934957.3 renin isoform X5 [Gallus gallus]	sp|Q6DYE7|RENI_CANLF	sp|Q6DYE7|RENI_CANLF Renin OS=Canis lupus familiaris GN=REN PE=2 SV=1	_	_	_	_	_	PF00026.20|Asp|Eukaryotic aspartyl protease|ENSGALT00000000757|m.7883:103-421;PF14543.3|TAXi_N|Xylanase inhibitor N-terminal|ENSGALT00000000757|m.7883:104-183;PF14541.3|TAXi_C|Xylanase inhibitor C-terminal|ENSGALT00000000757|m.7883:345-420;PF07966.9|A1_Propeptide|A1 Propeptide|ENSGALT00000000757|m.7883:50-72
ENSGALG00000000577	34.03990701	16.55888536	1.039174307	4.65E-22	4.93E-21	up	yes	34.00240428	35.62447565	32.4928411	17.5603062	12.97741729	19.1389326	28	832528	873641	+	RANBP3	protein_coding	GO:0000082|G1/S transition of mitotic cell cycle; GO:0006405|RNA export from nucleus; GO:0006511|ubiquitin-dependent protein catabolic process; GO:0006606|protein import into nucleus; GO:0007051|spindle organization; GO:0043547|positive regulation of GTPase activity; GO:0046604|positive regulation of mitotic centrosome separation	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005813|centrosome	GO:0008536|Ran GTPase binding; GO:0070412|R-SMAD binding	ko:K15304|RANBP3	ko05166|HTLV-I infection	3210	XP_004948717.1	XP_004948717.1 ran-binding protein 3 isoform X1 [Gallus gallus]	sp|Q9H6Z4|RANB3_HUMAN	sp|Q9H6Z4|RANB3_HUMAN Ran-binding protein 3 OS=Homo sapiens GN=RANBP3 PE=1 SV=1	9031.ENSGALP00000000805	RAN binding protein 3	_	KOG0866	_	PF00638.15|Ran_BP1|RanBP1 domain|ENSGALT00000097326|m.9557:411-518
ENSGALG00000000611	32.69584069	14.47294281	1.175193523	1.94E-53	7.96E-52	up	yes	31.56241223	33.46220434	33.0629055	15.68760568	14.45137353	13.27984922	26	1783984	1790373	-	ENSGALG00000000611	protein_coding	GO:0001933|negative regulation of protein phosphorylation; GO:0006983|ER overload response; GO:0042542|response to hydrogen peroxide; GO:0070262|peptidyl-serine dephosphorylation; GO:1903898|negative regulation of PERK-mediated unfolded protein response; GO:1903912|negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation	GO:0000164|protein phosphatase type 1 complex	GO:0019888|protein phosphatase regulator activity	"ko:K17558|PPP1R15B,CREP"	--	3631	XP_003642789.3	XP_003642789.3 protein phosphatase 1 regulatory subunit 15B [Gallus gallus]	sp|Q5SWA1|PR15B_HUMAN	sp|Q5SWA1|PR15B_HUMAN Protein phosphatase 1 regulatory subunit 15B OS=Homo sapiens GN=PPP1R15B PE=1 SV=1	9031.ENSGALP00000000862	annotation not avaliable	_	_	NOG252208	PF10488.6|PP1c_bdg|Phosphatase-1 catalytic subunit binding region|ENSGALT00000000864|m.7906:40-322
ENSGALG00000000616	16.18358573	45.64820886	-1.495451789	1.43E-64	8.20E-63	down	yes	17.61486518	15.58832219	15.34756982	45.88979741	45.85216406	45.20266512	26	323882	327166	+	ELF3	protein_coding	"GO:0001824|blastocyst development; GO:0006355|regulation of transcription, DNA-templated; GO:0006954|inflammatory response; GO:0009653|anatomical structure morphogenesis; GO:0030154|cell differentiation; GO:0030198|extracellular matrix organization; GO:0030855|epithelial cell differentiation; GO:0045892|negative regulation of transcription, DNA-templated; GO:0045893|positive regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0060056|mammary gland involution"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005794|Golgi apparatus; GO:0005829|cytosol	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity; GO:0003713|transcription coactivator activity"	"ko:K09429|K09429,ELF3"	--	1373	XP_419257.4	XP_419257.4 ETS-related transcription factor Elf-3 [Gallus gallus]	sp|Q3UPW2|ELF3_MOUSE	sp|Q3UPW2|ELF3_MOUSE ETS-related transcription factor Elf-3 OS=Mus musculus GN=Elf3 PE=1 SV=1	9031.ENSGALP00000000871	"E74-like factor 3 (ets domain transcription factor, epithelial-specific )"	_	KOG3804	_	PF00178.19|Ets|Ets-domain|ENSGALT00000000873|m.7488:303-383;PF02198.13|SAM_PNT|Sterile alpha motif (SAM)/Pointed domain|ENSGALT00000000873|m.7488:87-161
ENSGALG00000000619	11.28638648	26.45279297	-1.228103983	0.000903112	0.001915447	down	yes	11.63111527	11.13556968	11.09247451	32.82415501	32.13403991	14.40018398	28	945364	954006	-	ANGPTL4	protein_coding	GO:0001525|angiogenesis; GO:0030154|cell differentiation; GO:0051005|negative regulation of lipoprotein lipase activity; GO:0070328|triglyceride homeostasis; GO:2000352|negative regulation of endothelial cell apoptotic process	GO:0031012|extracellular matrix; GO:0072562|blood microparticle	GO:0004857|enzyme inhibitor activity; GO:0042802|identical protein binding	"ko:K08767|ANGPTL4,PGAR"	ko03320|PPAR signaling pathway	3452	XP_001232284.3	XP_001232284.3 angiopoietin-related protein 4 [Gallus gallus]	sp|Q2TNK5|ANGL4_PIG	sp|Q2TNK5|ANGL4_PIG Angiopoietin-related protein 4 OS=Sus scrofa GN=ANGPTL4 PE=2 SV=2	_	_	_	_	_	"PF00147.15|Fibrinogen_C|Fibrinogen beta and gamma chains, C-terminal globular domain|ENSGALT00000104951|m.9572:217-429"
ENSGALG00000000681	1.607762653	3.286014027	-1.026722421	7.59E-09	3.03E-08	down	yes	2.027171018	1.497583578	1.298533363	3.315792341	3.455979821	3.086269919	1	194484628	194551701	+	PAK1	protein_coding	GO:0001934|positive regulation of protein phosphorylation; GO:0006468|protein phosphorylation; GO:0006887|exocytosis; GO:0006915|apoptotic process; GO:0007266|Rho protein signal transduction; GO:0007346|regulation of mitotic cell cycle; GO:0008284|positive regulation of cell population proliferation; GO:0016477|cell migration; GO:0023014|signal transduction by protein phosphorylation; GO:0030036|actin cytoskeleton organization; GO:0030335|positive regulation of cell migration; GO:0031098|stress-activated protein kinase signaling cascade; GO:0031116|positive regulation of microtubule polymerization; GO:0031532|actin cytoskeleton reorganization; GO:0032147|activation of protein kinase activity; GO:0033138|positive regulation of peptidyl-serine phosphorylation; GO:0033148|positive regulation of intracellular estrogen receptor signaling pathway; GO:0042060|wound healing; GO:0042981|regulation of apoptotic process; GO:0043408|regulation of MAPK cascade; GO:0043507|positive regulation of JUN kinase activity; GO:0046777|protein autophosphorylation; GO:0048012|hepatocyte growth factor receptor signaling pathway; GO:0048754|branching morphogenesis of an epithelial tube; GO:0050770|regulation of axonogenesis; GO:0051496|positive regulation of stress fiber assembly; GO:0060244|negative regulation of cell proliferation involved in contact inhibition	GO:0001726|ruffle; GO:0005737|cytoplasm; GO:0005794|Golgi apparatus; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0005911|cell-cell junction; GO:0005925|focal adhesion; GO:0032587|ruffle membrane; GO:0032991|protein-containing complex; GO:0071437|invadopodium	GO:0004674|protein serine/threonine kinase activity; GO:0005518|collagen binding; GO:0005524|ATP binding; GO:0048365|Rac GTPase binding	ko:K04409|PAK1	ko04010|MAPK signaling pathway; ko04011|MAPK signaling pathway - yeast; ko04012|ErbB signaling pathway; ko04014|Ras signaling pathway; ko04024|cAMP signaling pathway; ko04062|Chemokine signaling pathway; ko04360|Axon guidance; ko04392|Hippo signaling pathway -multiple species; ko04510|Focal adhesion; ko04650|Natural killer cell mediated cytotoxicity; ko04660|T cell receptor signaling pathway; ko04666|Fc gamma R-mediated phagocytosis; ko04810|Regulation of actin cytoskeleton; ko05120|Epithelial cell signaling in Helicobacter pylori infection; ko05205|Proteoglycans in cancer; ko05211|Renal cell carcinoma	3332	NP_001155844.1	NP_001155844.1 serine/threonine-protein kinase PAK 1 [Gallus gallus]	sp|Q08E52|PAK1_BOVIN	sp|Q08E52|PAK1_BOVIN Serine/threonine-protein kinase PAK 1 OS=Bos taurus GN=PAK1 PE=1 SV=1	9031.ENSGALP00000000961	p21 protein (Cdc42/Rac)-activated kinase 1 (EC:2.7.11.1)	COG0515	KOG0578	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000000963|m.4818:269-520;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000000963|m.4818:273-516;PF00786.25|PBD|P21-Rho-binding domain|ENSGALT00000000963|m.4818:74-132
ENSGALG00000000719	184.6121833	91.30284531	1.015686182	1.06E-39	2.59E-38	up	yes	177.0204055	188.2704648	188.5456795	95.25200791	97.51096667	81.14556134	21	640004	645489	+	RPL22	protein_coding	GO:0002181|cytoplasmic translation; GO:0046632|alpha-beta T cell differentiation	GO:0005634|nucleus; GO:0005925|focal adhesion; GO:0022625|cytosolic large ribosomal subunit; GO:0031012|extracellular matrix; GO:0070062|extracellular exosome	GO:0003723|RNA binding; GO:0003735|structural constituent of ribosome; GO:0008201|heparin binding	"ko:K02891|RP-L22e,RPL22"	ko03010|Ribosome	747	XP_005298479.1	XP_005298479.1 60S ribosomal protein L22 [Chrysemys picta bellii]	sp|Q98TF8|RL22_CHICK	sp|Q98TF8|RL22_CHICK 60S ribosomal protein L22 OS=Gallus gallus GN=RPL22 PE=2 SV=1	10141.ENSCPOP00000015486	ribosomal protein L22	_	KOG3434	_	PF01776.14|Ribosomal_L22e|Ribosomal L22e protein family|ENSGALT00000085554|m.3797:111-219
ENSGALG00000000791	7.653611367	3.437576215	1.152441956	4.11E-19	3.66E-18	up	yes	6.735110986	8.084921791	8.140801324	3.572333465	3.411567766	3.328827413	26	2384160	2390966	-	ENSGALG00000000791	protein_coding	--	GO:0005739|mitochondrion	--	--	--	2405	XP_417970.4	XP_417970.4 protein FAM72A isoform X1 [Gallus gallus]	sp|A6QL50|FA72A_BOVIN	sp|A6QL50|FA72A_BOVIN Protein FAM72A OS=Bos taurus GN=FAM72A PE=1 SV=1	9031.ENSGALP00000001147	similar to RIKEN cDNA 2700049P18	_	_	NOG42824	PF14976.3|FAM72|FAM72 protein|ENSGALT00000001149|m.8010:1-120
ENSGALG00000000803	1.081519824	2.658942043	-1.289929645	0.000171634	0.000406559	down	yes	1.266612719	0.742945236	1.235001516	2.953891292	2.043838059	2.979096778	28	2045697	2048418	+	ENSGALG00000000803	protein_coding	--	--	--	--	--	1040	XP_003642901.1	XP_003642901.1 uncharacterized protein LOC100859850 [Gallus gallus]	_	_	9031.ENSGALP00000001162	annotation not avaliable	_	_	NOG82759	_
ENSGALG00000000806	0.136987312	0.480740186	-1.739267792	0.003411214	0.006569605	down	yes	0.173897984	0.148752512	0.08831144	0.523291292	0.401193433	0.517735831	28	2069057	2070874	+	LINGO3	protein_coding	--	GO:0005615|extracellular space; GO:0016021|integral component of membrane; GO:0031012|extracellular matrix	--	--	--	1818	XP_418194.1	XP_418194.1 leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3 [Gallus gallus]	sp|P0C6S8|LIGO3_HUMAN	sp|P0C6S8|LIGO3_HUMAN Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3 OS=Homo sapiens GN=LINGO3 PE=3 SV=1	9031.ENSGALP00000001166	leucine rich repeat and Ig domain containing 3	_	KOG0619	_	PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000001168|m.9847:81-140;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000001168|m.9847:146-188;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000001168|m.9847:249-305;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000001168|m.9847:297-356;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000001168|m.9847:82-161;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000001168|m.9847:145-270;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000001168|m.9847:239-352;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000001168|m.9847:414-499;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000001168|m.9847:408-486;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000001168|m.9847:417-496;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000001168|m.9847:408-492;PF00560.30|LRR_1|Leucine Rich Repeat|ENSGALT00000001168|m.9847:274-294
ENSGALG00000000820	1.117162043	0.400584309	1.456944535	5.83E-07	1.91E-06	up	yes	1.067032663	1.303915458	0.980538009	0.458699889	0.308132474	0.434920565	23	1741624	1757003	+	ENSGALG00000000820	protein_coding	"GO:0007187|G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; GO:0007193|adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; GO:0007268|chemical synaptic transmission; GO:0009636|response to toxic substance; GO:0014827|intestine smooth muscle contraction; GO:0040012|regulation of locomotion; GO:0042310|vasoconstriction; GO:0050795|regulation of behavior"	GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane	GO:0004993|G protein-coupled serotonin receptor activity; GO:0030594|neurotransmitter receptor activity; GO:0051378|serotonin binding	ko:K04153|HTR1	ko04024|cAMP signaling pathway; ko04080|Neuroactive ligand-receptor interaction; ko04726|Serotonergic synapse; ko04742|Taste transduction	3111	XP_015153069.1	XP_015153069.1 5-hydroxytryptamine receptor 1D [Gallus gallus]	sp|P28221|5HT1D_HUMAN	sp|P28221|5HT1D_HUMAN 5-hydroxytryptamine receptor 1D OS=Homo sapiens GN=HTR1D PE=1 SV=1	9031.ENSGALP00000001192	5-hydroxytryptamine (serotonin) receptor 1D	_	KOG3656	_	PF00001.18|7tm_1|7 transmembrane receptor (rhodopsin family)|ENSGALT00000001194|m.5241:56-356;PF10320.6|7TM_GPCR_Srsx|Serpentine type 7TM GPCR chemoreceptor Srsx|ENSGALT00000001194|m.5241:53-370
ENSGALG00000000824	0.884938566	0.233737027	1.876463218	5.11E-05	0.000130877	up	yes	1.18606841	0.565257152	0.903490136	0.301142801	0.23454286	0.165525419	27	3764703	3768368	+	ENSGALG00000000824	protein_coding	GO:0006939|smooth muscle contraction; GO:0030335|positive regulation of cell migration	GO:0005829|cytosol; GO:0016020|membrane	GO:0004687|myosin light chain kinase activity; GO:0005516|calmodulin binding; GO:0005524|ATP binding; GO:0046872|metal ion binding	ko:K00907|MYLK	ko04020|Calcium signaling pathway; ko04022|cGMP-PKG signaling pathway; ko04270|Vascular smooth muscle contraction; ko04371|Apelin signaling pathway; ko04510|Focal adhesion; ko04611|Platelet activation; ko04810|Regulation of actin cytoskeleton; ko04921|Oxytocin signaling pathway; ko04971|Gastric acid secretion	1735	POI30242.1	POI30242.1 hypothetical protein CIB84_006008 [Bambusicola thoracicus]	sp|P11799|MYLK_CHICK	"sp|P11799|MYLK_CHICK Myosin light chain kinase, smooth muscle OS=Gallus gallus GN=Mylk PE=1 SV=2"	9031.ENSGALP00000001197	hypothetical LOC428278	COG0515	KOG0613	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000001199|m.8644:27-282;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000001199|m.8644:30-271
ENSGALG00000000913	9.576591759	4.009719138	1.253923295	1.25E-35	2.57E-34	up	yes	9.639335044	9.506530461	9.583909772	3.770406263	4.29178556	3.966965592	11	19912187	19927726	+	CHST6	protein_coding	GO:0005975|carbohydrate metabolic process; GO:0006044|N-acetylglucosamine metabolic process; GO:0006790|sulfur compound metabolic process; GO:0018146|keratan sulfate biosynthetic process	GO:0000139|Golgi membrane; GO:0005794|Golgi apparatus; GO:0016021|integral component of membrane	GO:0001517|N-acetylglucosamine 6-O-sulfotransferase activity	ko:K09671|CHST6	ko00533|Glycosaminoglycan biosynthesis - keratan sulfate	3052	OXB78347.1	OXB78347.1 hypothetical protein H355_009118 [Colinus virginianus]	sp|Q9GZX3|CHST6_HUMAN	sp|Q9GZX3|CHST6_HUMAN Carbohydrate sulfotransferase 6 OS=Homo sapiens GN=CHST6 PE=1 SV=1	9031.ENSGALP00000001340	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6	_	_	NOG251104	PF00685.24|Sulfotransfer_1|Sulfotransferase domain|ENSGALT00000001342|m.7066:44-352;PF13469.3|Sulfotransfer_3|Sulfotransferase family|ENSGALT00000001342|m.7066:197-297
ENSGALG00000000934	13.22910601	6.232469104	1.084617025	5.18E-18	4.28E-17	up	yes	13.01120925	13.6305848	13.04552399	5.712534211	7.565474342	5.419398758	17	10544180	10549641	+	ZBTB43	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated"	GO:0005634|nucleus	GO:0003677|DNA binding; GO:0046872|metal ion binding	ko:K10514|ZBTB43	--	2446	XP_017693934.1	XP_017693934.1 PREDICTED: zinc finger and BTB domain-containing protein 43 isoform X1 [Lepidothrix coronata]	sp|O43298|ZBT43_HUMAN	sp|O43298|ZBT43_HUMAN Zinc finger and BTB domain-containing protein 43 OS=Homo sapiens GN=ZBTB43 PE=1 SV=1	9031.ENSGALP00000001370	zinc finger and BTB domain containing 43	COG5048	KOG1721	_	PF00651.28|BTB|BTB/POZ domain|ENSGALT00000001372|m.12450:23-125
ENSGALG00000000949	2.106468747	5.870556115	-1.474293409	2.74E-10	1.25E-09	down	yes	2.562880674	2.102051155	1.654474413	6.372354909	4.724453106	6.51486033	13	2173845	2180352	-	HBEGF	protein_coding	"GO:0007173|epidermal growth factor receptor signaling pathway; GO:0008016|regulation of heart contraction; GO:0008284|positive regulation of cell population proliferation; GO:0021545|cranial nerve development; GO:0035313|wound healing, spreading of epidermal cells; GO:0048661|positive regulation of smooth muscle cell proliferation; GO:0050731|positive regulation of peptidyl-tyrosine phosphorylation; GO:0051549|positive regulation of keratinocyte migration; GO:0051897|positive regulation of protein kinase B signaling; GO:0060326|cell chemotaxis; GO:0090303|positive regulation of wound healing"	GO:0005615|extracellular space; GO:0005887|integral component of plasma membrane; GO:0009986|cell surface	GO:0005154|epidermal growth factor receptor binding; GO:0008083|growth factor activity; GO:0008201|heparin binding	ko:K08523|HBEGF	ko01522|Endocrine resistance; ko04012|ErbB signaling pathway; ko04912|GnRH signaling pathway; ko04915|Estrogen signaling pathway; ko05120|Epithelial cell signaling in Helicobacter pylori infection; ko05205|Proteoglycans in cancer; ko05219|Bladder cancer	1213	NP_990180.1	NP_990180.1 proheparin-binding EGF-like growth factor precursor [Gallus gallus]	sp|Q9W7C5|HBEGF_CHICK	sp|Q9W7C5|HBEGF_CHICK Proheparin-binding EGF-like growth factor OS=Gallus gallus GN=HBEGF PE=1 SV=1	9031.ENSGALP00000001399	heparin-binding EGF-like growth factor 	_	_	NOG45526	PF00008.24|EGF|EGF-like domain|ENSGALT00000001401|m.8293:116-146;PF12661.4|hEGF|Human growth factor-like EGF|ENSGALT00000001401|m.8293:136-147
ENSGALG00000000950	10.22813367	4.780538327	1.095693058	0.001930613	0.00388599	up	yes	9.99675801	9.19365651	11.4939865	2.722170464	5.923106876	5.696337641	17	10262203	10310998	+	MVB12B	protein_coding	GO:0015031|protein transport; GO:0016197|endosomal transport; GO:0019058|viral life cycle; GO:0019075|virus maturation; GO:0042058|regulation of epidermal growth factor receptor signaling pathway; GO:0043162|ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; GO:0048524|positive regulation of viral process; GO:0075733|intracellular transport of virus	GO:0000813|ESCRT I complex; GO:0005634|nucleus; GO:0005769|early endosome; GO:0005770|late endosome; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0010008|endosome membrane; GO:0031902|late endosome membrane; GO:0031982|vesicle; GO:0043657|host cell; GO:0070062|extracellular exosome	GO:0008289|lipid binding	ko:K12186|FAM125	ko04144|Endocytosis	5525	XP_015734971.1	XP_015734971.1 PREDICTED: multivesicular body subunit 12B isoform X1 [Coturnix japonica]	sp|Q9H7P6|MB12B_HUMAN	sp|Q9H7P6|MB12B_HUMAN Multivesicular body subunit 12B OS=Homo sapiens GN=MVB12B PE=1 SV=2	9031.ENSGALP00000001400	hypothetical protein LOC417092 	_	KOG4000	_	PF10240.6|DUF2464|Protein of unknown function (DUF2464)|ENSGALT00000001402|m.12443:17-268
ENSGALG00000001014	31.48523951	14.721375	1.096241687	7.52E-24	8.79E-23	up	yes	28.56260131	32.51095876	33.38215846	15.53081374	14.55323069	14.08008056	17	9879987	9883662	-	ARPC5L	protein_coding	GO:0016477|cell migration; GO:0034314|Arp2/3 complex-mediated actin nucleation	GO:0005737|cytoplasm; GO:0005885|Arp2/3 protein complex; GO:0005925|focal adhesion; GO:0042995|cell projection; GO:0070062|extracellular exosome	GO:0051015|actin filament binding	ko:K05754|ARPC5	ko04144|Endocytosis; ko04666|Fc gamma R-mediated phagocytosis; ko04810|Regulation of actin cytoskeleton; ko05100|Bacterial invasion of epithelial cells; ko05130|Pathogenic Escherichia coli infection; ko05131|Shigellosis; ko05132|Salmonella infection	915	XP_015135338.1	XP_015135338.1 actin-related protein 2/3 complex subunit 5-like protein [Gallus gallus]	sp|Q5E963|ARP5L_BOVIN	sp|Q5E963|ARP5L_BOVIN Actin-related protein 2/3 complex subunit 5-like protein OS=Bos taurus GN=ARPC5L PE=2 SV=1	_	_	_	_	_	PF04699.11|P16-Arc|ARP2/3 complex 16 kDa subunit (p16-Arc)|ENSGALT00000001496|m.12415:46-125
ENSGALG00000001035	3.783453231	8.307479457	-1.132634647	6.40E-08	2.32E-07	down	yes	4.786672615	3.233246651	3.330440426	10.74628079	6.573717969	7.602439615	28	2283963	2295801	-	ENSGALG00000001035	protein_coding	"GO:0006355|regulation of transcription, DNA-templated; GO:0006367|transcription initiation from RNA polymerase II promoter; GO:0007601|visual perception; GO:0035881|amacrine cell differentiation; GO:0042462|eye photoreceptor cell development; GO:0042752|regulation of circadian rhythm; GO:0045668|negative regulation of osteoblast differentiation; GO:0045892|negative regulation of transcription, DNA-templated; GO:0045893|positive regulation of transcription, DNA-templated; GO:0046548|retinal rod cell development; GO:0046549|retinal cone cell development; GO:0048511|rhythmic process; GO:0060041|retina development in camera-type eye; GO:0071300|cellular response to retinoic acid"	GO:0005634|nucleus; GO:0005654|nucleoplasm	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003700|DNA-binding transcription factor activity; GO:0003707|steroid hormone receptor activity; GO:0004879|nuclear receptor activity; GO:0008134|transcription factor binding; GO:0008270|zinc ion binding"	"ko:K08533|NR1F2,RORB"	ko04710|Circadian rhythm	1398	XP_003642912.2	XP_003642912.2 nuclear receptor ROR-beta-like isoform X1 [Gallus gallus]	sp|Q92753|RORB_HUMAN	sp|Q92753|RORB_HUMAN Nuclear receptor ROR-beta OS=Homo sapiens GN=RORB PE=1 SV=3	_	_	_	_	_	"PF00105.15|zf-C4|Zinc finger, C4 type (two domains)|ENSGALT00000001533|m.9889:9-77;PF00104.27|Hormone_recep|Ligand-binding domain of nuclear hormone receptor|ENSGALT00000001533|m.9889:260-436"
ENSGALG00000001037	8.692546067	21.80226842	-1.325630363	4.73E-37	1.05E-35	down	yes	8.70775815	9.202934542	8.166945509	20.26228033	23.90036562	21.2441593	17	9826144	9857169	+	SCAI	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated; GO:0030336|negative regulation of cell migration; GO:0035024|negative regulation of Rho protein signal transduction"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0016021|integral component of membrane; GO:0031965|nuclear membrane	GO:0003714|transcription corepressor activity	--	--	1929	XP_015135330.1	XP_015135330.1 protein SCAI isoform X1 [Gallus gallus]	sp|Q8N9R8|SCAI_HUMAN	sp|Q8N9R8|SCAI_HUMAN Protein SCAI OS=Homo sapiens GN=SCAI PE=1 SV=2	_	_	_	_	_	PF12070.5|DUF3550|Protein of unknown function (DUF3550/UPF0682)|ENSGALT00000001535|m.12408:100-592
ENSGALG00000001096	54.44856891	26.08279585	1.061507533	8.22E-16	5.82E-15	up	yes	44.60898978	57.41101915	61.32569779	23.29402001	29.01703999	25.93732754	28	2523110	2525051	+	UQCR11	protein_coding	--	GO:0005743|mitochondrial inner membrane; GO:0016021|integral component of membrane; GO:0070469|respirasome	GO:0008121|ubiquinol-cytochrome-c reductase activity	"ko:K00420|QCR10,UQCR"	ko00190|Oxidative phosphorylation; ko01100|Metabolic pathways; ko04260|Cardiac muscle contraction; ko04932|Non-alcoholic fatty liver disease (NAFLD); ko05010|Alzheimer's disease; ko05012|Parkinson's disease; ko05016|Huntington's disease	502	NP_001177731.1	NP_001177731.1 cytochrome b-c1 complex subunit 10 [Gallus gallus]	sp|P07552|QCR10_BOVIN	sp|P07552|QCR10_BOVIN Cytochrome b-c1 complex subunit 10 OS=Bos taurus GN=UQCR11 PE=1 SV=2	9031.ENSGALP00000001640	"ubiquinol-cytochrome c reductase, 6.4kDa subunit"	_	_	NOG70565	_
ENSGALG00000001136	1.177883593	4.636105046	-1.967628308	2.55E-13	1.50E-12	down	yes	0.750585315	1.210725571	1.572339893	5.519577038	4.170795168	4.21794293	21	1417763	1419447	-	ENSGALG00000001136	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006351|transcription, DNA-templated; GO:0007155|cell adhesion; GO:0007219|Notch signaling pathway; GO:0007224|smoothened signaling pathway; GO:0007420|brain development; GO:0008284|positive regulation of cell population proliferation; GO:0014003|oligodendrocyte development; GO:0021537|telencephalon development; GO:0021781|glial cell fate commitment; GO:0021861|forebrain radial glial cell differentiation; GO:0021915|neural tube development; GO:0022010|central nervous system myelination; GO:0030182|neuron differentiation; GO:0030513|positive regulation of BMP signaling pathway; GO:0031641|regulation of myelination; GO:0042491|inner ear auditory receptor cell differentiation; GO:0042531|positive regulation of tyrosine phosphorylation of STAT protein; GO:0042668|auditory receptor cell fate determination; GO:0043010|camera-type eye development; GO:0045595|regulation of cell differentiation; GO:0045607|regulation of inner ear auditory receptor cell differentiation; GO:0045665|negative regulation of neuron differentiation; GO:0045747|positive regulation of Notch signaling pathway; GO:0045892|negative regulation of transcription, DNA-templated; GO:0045893|positive regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0046427|positive regulation of receptor signaling pathway via JAK-STAT; GO:0048469|cell maturation; GO:0048661|positive regulation of smooth muscle cell proliferation; GO:0048708|astrocyte differentiation; GO:0048712|negative regulation of astrocyte differentiation; GO:0048715|negative regulation of oligodendrocyte differentiation; GO:0050678|regulation of epithelial cell proliferation; GO:0050767|regulation of neurogenesis; GO:0051216|cartilage development; GO:0060122|inner ear receptor cell stereocilium organization; GO:0065003|protein-containing complex assembly; GO:0072049|comma-shaped body morphogenesis; GO:0072050|S-shaped body morphogenesis; GO:0072086|specification of loop of Henle identity; GO:0072282|metanephric nephron tubule morphogenesis; GO:0090162|establishment of epithelial cell polarity; GO:0097150|neuronal stem cell population maintenance; GO:2000737|negative regulation of stem cell differentiation; GO:2000974|negative regulation of pro-B cell differentiation; GO:2000978|negative regulation of forebrain neuron differentiation; GO:2000981|negative regulation of inner ear receptor cell differentiation"	GO:0005634|nucleus	"GO:0001227|DNA-binding transcription repressor activity, RNA polymerase II-specific; GO:0003682|chromatin binding; GO:0003690|double-stranded DNA binding; GO:0046983|protein dimerization activity"	ko:K06055|HES5	ko04330|Notch signaling pathway; ko05224|Breast cancer	1404	XP_024998267.1	XP_024998267.1 hairy and enhancer of split 5-like isoform X1 [Gallus gallus]	sp|Q03062|HES5_RAT	sp|Q03062|HES5_RAT Transcription factor HES-5 OS=Rattus norvegicus GN=Hes5 PE=2 SV=1	9031.ENSGALP00000001706	similar to enhancer of split related protein-7	_	KOG4304	_	PF00010.23|HLH|Helix-loop-helix DNA-binding domain|ENSGALT00000035200|m.3847:42-92;PF07527.10|Hairy_orange|Hairy Orange|ENSGALT00000035200|m.3847:111-148
ENSGALG00000001153	9.90985962	22.73605822	-1.197224945	2.78E-36	5.90E-35	down	yes	9.819958033	10.39885968	9.510761142	25.40251123	22.91971753	19.88594589	19	1512994	2173032	-	AUTS2	protein_coding	"GO:0001764|neuron migration; GO:0006351|transcription, DNA-templated; GO:0010592|positive regulation of lamellipodium assembly; GO:0031532|actin cytoskeleton reorganization; GO:0035022|positive regulation of Rac protein signal transduction; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0048675|axon extension; GO:0051571|positive regulation of histone H3-K4 methylation; GO:0060013|righting reflex; GO:0097484|dendrite extension; GO:0098582|innate vocalization behavior; GO:2000620|positive regulation of histone H4-K16 acetylation"	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0015629|actin cytoskeleton; GO:0030426|growth cone	GO:0003682|chromatin binding	--	--	3756	XP_415729.2	XP_415729.2 autism susceptibility gene 2 protein isoform X3 [Gallus gallus]	sp|Q8WXX7|AUTS2_HUMAN	sp|Q8WXX7|AUTS2_HUMAN Autism susceptibility gene 2 protein OS=Homo sapiens GN=AUTS2 PE=1 SV=1	9031.ENSGALP00000001729	autism susceptibility candidate 2	_	_	NOG41815	PF15336.3|Auts2|Autism susceptibility gene 2 protein|ENSGALT00000001731|m.13592:640-852
ENSGALG00000001161	0.148545276	0.367009817	-1.249707201	0.005169738	0.009665974	down	yes	0.114421475	0.167787849	0.163426504	0.419634446	0.3620262	0.319368805	24	1016857	1089783	+	FLI1	protein_coding	"GO:0006357|regulation of transcription by RNA polymerase II; GO:0007599|hemostasis; GO:0008015|blood circulation; GO:0009887|animal organ morphogenesis; GO:0030154|cell differentiation; GO:0035855|megakaryocyte development; GO:0045893|positive regulation of transcription, DNA-templated"	GO:0005634|nucleus; GO:0005829|cytosol; GO:0016604|nuclear body	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0000980|RNA polymerase II distal enhancer sequence-specific DNA binding; GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003677|DNA binding; GO:0003682|chromatin binding; GO:0003700|DNA-binding transcription factor activity"	ko:K09436|FLI1	ko05202|Transcriptional misregulation in cancer	3501	XP_009271268.1	XP_009271268.1 PREDICTED: Friend leukemia integration 1 transcription factor isoform X5 [Aptenodytes forsteri]	sp|Q01543|FLI1_HUMAN	sp|Q01543|FLI1_HUMAN Friend leukemia integration 1 transcription factor OS=Homo sapiens GN=FLI1 PE=1 SV=1	_	_	_	_	_	PF00178.19|Ets|Ets-domain|ENSGALT00000073643|m.6071:262-340;PF02198.13|SAM_PNT|Sterile alpha motif (SAM)/Pointed domain|ENSGALT00000073643|m.6071:115-197
ENSGALG00000001172	5.238038881	1.971926824	1.404874712	3.78E-17	2.94E-16	up	yes	4.767447217	5.492922978	5.453746449	1.518340738	2.443933649	1.953506084	21	1446518	1468998	-	KBP	protein_coding	--	GO:0016021|integral component of membrane; GO:0030054|cell junction; GO:0045211|postsynaptic membrane	GO:0004970|ionotropic glutamate receptor activity; GO:0005234|extracellularly glutamate-gated ion channel activity	--	--	3172	NP_990684.1	NP_990684.1 probable glutamate receptor precursor [Gallus gallus]	sp|P19439|GLRK_CHICK	sp|P19439|GLRK_CHICK Probable glutamate receptor OS=Gallus gallus GN=KBP PE=1 SV=1	9031.ENSGALP00000001774	Probable glutamate receptor Precursor (Kainate-binding protein); Receptor for glutamate. L-g [...] 	_	KOG1052	_	"PF00060.23|Lig_chan|Ligand-gated ion channel|ENSGALT00000001776|m.3851:168-431;PF10613.6|Lig_chan-Glu_bd|Ligated ion channel L-glutamate- and glycine-binding site|ENSGALT00000001776|m.3851:49-152;PF00497.17|SBP_bac_3|Bacterial extracellular solute-binding proteins, family 3|ENSGALT00000001776|m.3851:56-400"
ENSGALG00000001229	13.1919447	27.23610423	-1.045299502	2.06E-29	3.12E-28	down	yes	14.61815169	11.56867973	13.38900267	27.26021177	28.57829013	25.86981079	21	1681755	1772379	-	SKI	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0030512|negative regulation of transforming growth factor beta receptor signaling pathway; GO:0030514|negative regulation of BMP signaling pathway; GO:0045596|negative regulation of cell differentiation; GO:0048666|neuron development"	GO:0005634|nucleus; GO:0005667|transcription factor complex	GO:0019904|protein domain specific binding; GO:0042803|protein homodimerization activity; GO:0043565|sequence-specific DNA binding; GO:0046332|SMAD binding; GO:0046982|protein heterodimerization activity; GO:0070491|repressing transcription factor binding	--	--	2725	XP_024998314.1	XP_024998314.1 ski oncogene isoform X1 [Gallus gallus]	sp|P49140|SKI_CHICK	sp|P49140|SKI_CHICK Ski oncogene OS=Gallus gallus GN=SKI PE=1 SV=1	_	_	_	_	_	PF02437.14|Ski_Sno|SKI/SNO/DAC family|ENSGALT00000001864|m.3857:69-173;PF08782.7|c-SKI_SMAD_bind|c-SKI Smad4 binding domain|ENSGALT00000001864|m.3857:198-292
ENSGALG00000001252	4.797246579	10.45865883	-1.122793916	3.22E-20	3.07E-19	down	yes	4.579919153	4.746404837	5.065415746	9.814581855	11.55600907	10.00538557	28	2707242	2712155	-	CREB3L3	protein_coding	GO:0002675|positive regulation of acute inflammatory response; GO:0030968|endoplasmic reticulum unfolded protein response; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:1990440|positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	GO:0000139|Golgi membrane; GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005783|endoplasmic reticulum; GO:0005789|endoplasmic reticulum membrane; GO:0005829|cytosol; GO:0016020|membrane; GO:0016021|integral component of membrane	"GO:0000976|transcription regulatory region sequence-specific DNA binding; GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0035497|cAMP response element binding; GO:0042803|protein homodimerization activity; GO:0046982|protein heterodimerization activity"	ko:K09048|CREB3	ko04022|cGMP-PKG signaling pathway; ko04024|cAMP signaling pathway; ko04151|PI3K-Akt signaling pathway; ko04152|AMPK signaling pathway; ko04211|Longevity regulating pathway; ko04261|Adrenergic signaling in cardiomyocytes; ko04668|TNF signaling pathway; ko04725|Cholinergic synapse; ko04728|Dopaminergic synapse; ko04911|Insulin secretion; ko04915|Estrogen signaling pathway; ko04916|Melanogenesis; ko04918|Thyroid hormone synthesis; ko04922|Glucagon signaling pathway; ko04925|Aldosterone synthesis and secretion; ko04931|Insulin resistance; ko04962|Vasopressin-regulated water reabsorption; ko05016|Huntington's disease; ko05030|Cocaine addiction; ko05031|Amphetamine addiction; ko05034|Alcoholism; ko05161|Hepatitis B; ko05203|Viral carcinogenesis; ko05215|Prostate cancer	2393	XP_004948873.2	XP_004948873.2 cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1 [Gallus gallus]	sp|Q68CJ9|CR3L3_HUMAN	sp|Q68CJ9|CR3L3_HUMAN Cyclic AMP-responsive element-binding protein 3-like protein 3 OS=Homo sapiens GN=CREB3L3 PE=1 SV=2	9031.ENSGALP00000001898	cAMP responsive element binding protein 3-like 3	_	KOG0709	_	PF00170.18|bZIP_1|bZIP transcription factor|ENSGALT00000001900|m.9970:262-324;PF07716.12|bZIP_2|Basic region leucine zipper|ENSGALT00000001900|m.9970:266-316;PF03131.14|bZIP_Maf|bZIP Maf transcription factor|ENSGALT00000001900|m.9970:257-328
ENSGALG00000001263	1.798100034	10.29761567	-2.511164248	1.55E-81	1.31E-79	down	yes	1.643055467	1.938581119	1.812663515	10.47103063	10.19548988	10.22632649	19	2867022	2901742	-	GTF2IRD1	protein_coding	"GO:0006355|regulation of transcription, DNA-templated; GO:0006366|transcription by RNA polymerase II; GO:0007275|multicellular organism development; GO:0014886|transition between slow and fast fiber"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005829|cytosol	"GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity"	"ko:K03121|TFII-I,GTF2I"	ko03022|Basal transcription factors; ko04022|cGMP-PKG signaling pathway; ko05168|Herpes simplex infection	2790	XP_015151447.1	XP_015151447.1 general transcription factor II-I repeat domain-containing protein 1 isoform X2 [Gallus gallus]	sp|Q9UHL9|GT2D1_HUMAN	sp|Q9UHL9|GT2D1_HUMAN General transcription factor II-I repeat domain-containing protein 1 OS=Homo sapiens GN=GTF2IRD1 PE=1 SV=1	9031.ENSGALP00000001924	"PREDICTED: Gallus gallus similar to general transcription factor 3 (LOC417487), mRNA"	_	_	NOG29608	PF02946.11|GTF2I|GTF2I-like repeat|ENSGALT00000001926|m.13607:123-197;PF02946.11|GTF2I|GTF2I-like repeat|ENSGALT00000001926|m.13607:351-425;PF02946.11|GTF2I|GTF2I-like repeat|ENSGALT00000001926|m.13607:546-619;PF02946.11|GTF2I|GTF2I-like repeat|ENSGALT00000001926|m.13607:689-763;PF02946.11|GTF2I|GTF2I-like repeat|ENSGALT00000001926|m.13607:786-858
ENSGALG00000001409	0.562550102	1.995396443	-1.808413618	7.97E-10	3.47E-09	down	yes	0.652117439	0.621572995	0.413959873	2.387516522	1.487281368	2.111391438	13	8854546	8878613	+	IL-12B	protein_coding	--	GO:0005615|extracellular space; GO:0016020|membrane	GO:0004896|cytokine receptor activity; GO:0005125|cytokine activity	ko:K05425|IL12B	ko04060|Cytokine-cytokine receptor interaction; ko04620|Toll-like receptor signaling pathway; ko04622|RIG-I-like receptor signaling pathway; ko04630|Jak-STAT signaling pathway; ko04658|Th1 and Th2 cell differentiation; ko04940|Type I diabetes mellitus; ko05133|Pertussis; ko05134|Legionellosis; ko05140|Leishmaniasis; ko05142|Chagas disease (American trypanosomiasis); ko05143|African trypanosomiasis; ko05145|Toxoplasmosis; ko05146|Amoebiasis; ko05152|Tuberculosis; ko05162|Measles; ko05164|Influenza A; ko05168|Herpes simplex infection; ko05205|Proteoglycans in cancer; ko05321|Inflammatory bowel disease (IBD); ko05330|Allograft rejection	1871	NP_998736.1	NP_998736.1 interleukin-12 subunit beta precursor [Gallus gallus]	sp|O02744|IL12B_FELCA	sp|O02744|IL12B_FELCA Interleukin-12 subunit beta OS=Felis catus GN=IL12B PE=2 SV=1	9031.ENSGALP00000040257	interleukin 12B 	_	_	NOG45642	PF10420.6|IL12p40_C|Cytokine interleukin-12p40 C-terminus|ENSGALT00000041052|m.8525:125-208
ENSGALG00000001437	0.856151759	1.834483905	-1.090525473	1.54E-05	4.23E-05	down	yes	0.990996353	0.822565343	0.754893581	1.491045931	1.723036914	2.289368871	24	1887297	2185646	+	NTM	protein_coding	GO:0007155|cell adhesion	GO:0005886|plasma membrane; GO:0031225|anchored component of membrane	--	ko:K06774|HNT	--	1973	BAA31514.1	BAA31514.1 CEPU-1 [Gallus gallus]	sp|Q90773|CEPU1_CHICK	sp|Q90773|CEPU1_CHICK Protein CEPU-1 OS=Gallus gallus PE=1 SV=1	59729.ENSTGUP00000000712	Neurotrimin Precursor (hNT) [Taeniopygia guttata]	_	KOG3510	_	PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000091599|m.6130:123-217;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000091599|m.6130:221-303;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000091599|m.6130:314-395;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000091599|m.6130:221-290;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000091599|m.6130:307-384;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000091599|m.6130:128-213;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000091599|m.6130:314-394;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000091599|m.6130:222-302;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000091599|m.6130:313-390;PF07686.14|V-set|Immunoglobulin V-set domain|ENSGALT00000091599|m.6130:129-217
ENSGALG00000001442	10.2010658	4.759687314	1.098166862	3.81E-14	2.39E-13	up	yes	10.51226162	11.49003236	8.600903415	5.028139762	4.735000083	4.515922098	24	2144948	2396494	-	OPCML	protein_coding	GO:0007155|cell adhesion	GO:0005886|plasma membrane; GO:0031225|anchored component of membrane	--	"ko:K06773|OPCML,OBCAM"	--	1549	XP_010721921.1	XP_010721921.1 PREDICTED: opioid-binding protein/cell adhesion molecule isoform X1 [Meleagris gallopavo]	sp|Q98892|OBCAM_CHICK	sp|Q98892|OBCAM_CHICK Opioid-binding protein/cell adhesion molecule homolog OS=Gallus gallus GN=OPCML PE=1 SV=2	_	_	_	_	_	PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000002194|m.6134:41-135;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000002194|m.6134:139-219;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000002194|m.6134:231-313;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000002194|m.6134:138-208;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000002194|m.6134:225-302;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000002194|m.6134:46-131;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000002194|m.6134:145-210;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000002194|m.6134:232-312;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000002194|m.6134:48-131;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000002194|m.6134:142-222;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000002194|m.6134:234-305;PF07686.14|V-set|Immunoglobulin V-set domain|ENSGALT00000002194|m.6134:47-135
ENSGALG00000001445	3.692649412	9.747985755	-1.398025424	3.15E-17	2.46E-16	down	yes	4.159822824	3.438709376	3.479416036	10.15527353	10.2098849	8.87879884	13	8593917	8632025	-	FABP6	protein_coding	GO:0006869|lipid transport; GO:0008206|bile acid metabolic process	GO:0005737|cytoplasm; GO:0016020|membrane	GO:0005215|transporter activity; GO:0032052|bile acid binding	ko:K08755|FABP6	ko03320|PPAR signaling pathway	1292	XP_013033960.1	XP_013033960.1 PREDICTED: gastrotropin isoform X2 [Anser cygnoides domesticus]	sp|P51162|FABP6_MOUSE	sp|P51162|FABP6_MOUSE Gastrotropin OS=Mus musculus GN=Fabp6 PE=2 SV=2	9031.ENSGALP00000002196	"fatty acid binding protein 6, ileal (gastrotropin)"	_	KOG4015	_	PF14651.3|Lipocalin_7|Lipocalin / cytosolic fatty-acid binding protein family|ENSGALT00000002198|m.8518:1-128
ENSGALG00000001463	6.905918108	2.923280062	1.237405964	1.02E-09	4.40E-09	up	yes	6.897904401	5.514360421	8.305489503	3.197258971	2.657693502	2.914887713	23	3357695	3366101	-	PDIK1L	protein_coding	--	GO:0005654|nucleoplasm	GO:0004674|protein serine/threonine kinase activity; GO:0005524|ATP binding	"ko:K17539|PDIK1L,CLIK1L"	--	1137	POI27291.1	"POI27291.1 hypothetical protein CIB84_008959, partial [Bambusicola thoracicus]"	sp|Q8QZR7|PDK1L_MOUSE	sp|Q8QZR7|PDK1L_MOUSE Serine/threonine-protein kinase PDIK1L OS=Mus musculus GN=Pdik1l PE=2 SV=1	_	_	_	_	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000002218|m.5448:50-361;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000002218|m.5448:52-128;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000002218|m.5448:156-359
ENSGALG00000001531	0.886943509	0.396801189	1.140693229	0.000351189	0.000794202	up	yes	1.066695696	0.795586731	0.798548101	0.345892805	0.392779473	0.45173129	18	3342109	3349216	-	ENSGALG00000001531	protein_coding	GO:0030389|fructosamine metabolic process; GO:0030393|fructoselysine metabolic process; GO:0030855|epithelial cell differentiation; GO:0043687|post-translational protein modification	GO:0005829|cytosol	GO:0016301|kinase activity; GO:0030387|fructosamine-3-kinase activity	ko:K15522|FN3K	--	2865	XP_415601.1	XP_415601.1 fructosamine-3-kinase isoform X1 [Gallus gallus]	sp|Q9H479|FN3K_HUMAN	sp|Q9H479|FN3K_HUMAN Fructosamine-3-kinase OS=Homo sapiens GN=FN3K PE=1 SV=1	9031.ENSGALP00000002326	fructosamine 3 kinase	COG3001	KOG3021	_	PF03881.11|Fructosamin_kin|Fructosamine kinase|ENSGALT00000002328|m.12607:22-310;PF01636.20|APH|Phosphotransferase enzyme family|ENSGALT00000002328|m.12607:23-252
ENSGALG00000001545	0.445711198	0.924788442	-1.036520074	0.004616545	0.008706453	down	yes	0.513308223	0.43281174	0.391013631	0.849551816	0.893250715	1.031562795	18	3365331	3388901	+	RAB40B	protein_coding	GO:0016567|protein ubiquitination; GO:0035556|intracellular signal transduction; GO:0072659|protein localization to plasma membrane; GO:1990967|multi-organism toxin transport	GO:0005635|nuclear envelope; GO:0005768|endosome; GO:0005886|plasma membrane; GO:0008021|synaptic vesicle; GO:0030667|secretory granule membrane; GO:0048471|perinuclear region of cytoplasm	GO:0003924|GTPase activity; GO:0005525|GTP binding	ko:K07928|RAB40	--	2053	NP_001264979.1	NP_001264979.1 ras-related protein Rab-40B [Gallus gallus]	sp|Q12829|RB40B_HUMAN	sp|Q12829|RB40B_HUMAN Ras-related protein Rab-40B OS=Homo sapiens GN=RAB40B PE=2 SV=1	9031.ENSGALP00000002347	"RAB40B, member RAS oncogene family"	COG1100	KOG0078	_	"PF00071.19|Ras|Ras family|ENSGALT00000002349|m.12610:16-174;PF08477.10|Roc|Ras of Complex, Roc, domain of DAPkinase|ENSGALT00000002349|m.12610:16-128;PF07525.13|SOCS_box|SOCS box|ENSGALT00000002349|m.12610:189-223;PF00025.18|Arf|ADP-ribosylation factor family|ENSGALT00000002349|m.12610:15-130"
ENSGALG00000001561	2.371345359	5.617060327	-1.240604565	4.40E-14	2.74E-13	down	yes	2.749512522	1.981187297	2.383336259	5.830884452	5.427736436	5.592560093	21	2245514	2268919	+	MXRA8	protein_coding	GO:0060857|establishment of glial blood-brain barrier	GO:0009986|cell surface; GO:0016021|integral component of membrane; GO:0070062|extracellular exosome	--	--	--	2089	XP_024998251.1	XP_024998251.1 matrix remodeling-associated protein 8 isoform X1 [Gallus gallus]	sp|Q90WI4|MXRA8_CHICK	sp|Q90WI4|MXRA8_CHICK Matrix remodeling-associated protein 8 OS=Gallus gallus GN=MXRA8 PE=2 SV=1	_	_	_	_	_	PF07686.14|V-set|Immunoglobulin V-set domain|ENSGALT00000104012|m.3915:42-156;PF07686.14|V-set|Immunoglobulin V-set domain|ENSGALT00000104012|m.3915:176-288
ENSGALG00000001564	18.34872066	6.651647196	1.462514671	7.88E-44	2.31E-42	up	yes	19.61988981	16.79615646	18.6301157	6.582702197	5.701475058	7.670764333	19	3422032	3455961	+	ATP2A3	protein_coding	--	GO:0016021|integral component of membrane; GO:0033017|sarcoplasmic reticulum membrane	"GO:0005388|calcium transmembrane transporter activity, phosphorylative mechanism; GO:0005524|ATP binding; GO:0046872|metal ion binding"	ko:K05853|ATP2A	ko04020|Calcium signaling pathway; ko04022|cGMP-PKG signaling pathway; ko04972|Pancreatic secretion; ko05010|Alzheimer's disease	3878	NP_990222.1	NP_990222.1 sarcoplasmic/endoplasmic reticulum calcium ATPase 3 [Gallus gallus]	sp|Q9YGL9|AT2A3_CHICK	sp|Q9YGL9|AT2A3_CHICK Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 OS=Gallus gallus GN=ATP2A3 PE=2 SV=1	9031.ENSGALP00000002373	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (EC 3.6.3.8)(ChkSERCA3)(SERCA3)(Calcium  [...] 	COG0474	KOG0202	_	"PF00122.17|E1-E2_ATPase|E1-E2 ATPase|ENSGALT00000002375|m.13630:122-370;PF00689.18|Cation_ATPase_C|Cation transporting ATPase, C-terminus|ENSGALT00000002375|m.13630:814-1017;PF13246.3|Cation_ATPase|Cation transport ATPase (P-type)|ENSGALT00000002375|m.13630:448-558;PF00690.23|Cation_ATPase_N|Cation transporter/ATPase, N-terminus|ENSGALT00000002375|m.13630:35-102;PF00702.23|Hydrolase|haloacid dehalogenase-like hydrolase|ENSGALT00000002375|m.13630:377-744;PF08282.9|Hydrolase_3|haloacid dehalogenase-like hydrolase|ENSGALT00000002375|m.13630:716-773"
ENSGALG00000001583	5.911567613	12.79149076	-1.112260769	4.25E-17	3.29E-16	down	yes	4.825476402	7.247282631	5.661943804	12.69102159	13.96714427	11.71630642	17	8597003	8608024	-	TRAF1	protein_coding	GO:0006915|apoptotic process; GO:0007165|signal transduction; GO:0051092|positive regulation of NF-kappaB transcription factor activity; GO:2001236|regulation of extrinsic apoptotic signaling pathway	GO:0005737|cytoplasm	GO:0005164|tumor necrosis factor receptor binding; GO:0008270|zinc ion binding; GO:0031625|ubiquitin protein ligase binding; GO:0031996|thioesterase binding; GO:0042802|identical protein binding	ko:K03172|TRAF1	ko04064|NF-kappa B signaling pathway; ko04210|Apoptosis; ko04668|TNF signaling pathway; ko05168|Herpes simplex infection; ko05169|Epstein-Barr virus infection; ko05200|Pathways in cancer; ko05202|Transcriptional misregulation in cancer; ko05203|Viral carcinogenesis; ko05222|Small cell lung cancer	2708	XP_024997266.1	XP_024997266.1 TNF receptor-associated factor 1 isoform X1 [Gallus gallus]	sp|P39428|TRAF1_MOUSE	sp|P39428|TRAF1_MOUSE TNF receptor-associated factor 1 OS=Mus musculus GN=Traf1 PE=1 SV=2	9031.ENSGALP00000002401	TNF receptor-associated factor 1	_	KOG0297	_	"PF16673.2|TRAF_BIRC3_bd|TNF receptor-associated factor BIRC3 binding domain|ENSGALT00000002404|m.12320:347-403;PF02176.15|zf-TRAF|TRAF-type zinc finger|ENSGALT00000002404|m.12320:152-206;PF00097.22|zf-C3HC4|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000002404|m.12320:60-99"
ENSGALG00000001608	0.241877264	0.581244683	-1.231034404	0.00106264	0.002229147	down	yes	0.273010824	0.24465439	0.207966577	0.547693477	0.467890727	0.728149843	22	2087959	2217683	+	UNC5D	protein_coding	GO:0006915|apoptotic process; GO:0007165|signal transduction; GO:0007411|axon guidance; GO:0021859|pyramidal neuron differentiation; GO:0098742|cell-cell adhesion via plasma-membrane adhesion molecules; GO:2001222|regulation of neuron migration	GO:0005886|plasma membrane; GO:0009986|cell surface; GO:0016021|integral component of membrane	--	ko:K07521|UNC5	ko04360|Axon guidance	3237	XP_424529.4	XP_424529.4 netrin receptor UNC5D isoform X1 [Gallus gallus]	sp|Q8K1S2|UNC5D_MOUSE	sp|Q8K1S2|UNC5D_MOUSE Netrin receptor UNC5D OS=Mus musculus GN=Unc5d PE=1 SV=1	9031.ENSGALP00000002444	unc-5 homolog D (C. elegans)	_	KOG1480	_	PF00791.17|ZU5|ZU5 domain|ENSGALT00000069231|m.4689:608-702;PF00531.19|Death|Death domain|ENSGALT00000069231|m.4689:922-993;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000069231|m.4689:224-312;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000069231|m.4689:229-299;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000069231|m.4689:320-366;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000069231|m.4689:378-423;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000069231|m.4689:229-300;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000069231|m.4689:232-311
ENSGALG00000001620	0.754165848	1.718639519	-1.17767936	0.000528882	0.001159377	down	yes	0.956820028	0.677350197	0.628327321	2.24631061	1.44843067	1.461177276	17	8579238	8586394	+	ENSGALG00000001620	protein_coding	GO:0010038|response to metal ion	--	GO:0005507|copper ion binding	ko:K03926|cutA	--	1597	XP_415407.5	XP_415407.5 protein CutA [Gallus gallus]	sp|Q7T3C3|CUTA_DANRE	sp|Q7T3C3|CUTA_DANRE Protein CutA homolog OS=Danio rerio GN=cuta PE=2 SV=1	9031.ENSGALP00000038103	cutA divalent cation tolerance homolog (E. coli)	COG1324	KOG3338	_	PF03091.12|CutA1|CutA1 divalent ion tolerance protein|ENSGALT00000002476|m.12317:75-171
ENSGALG00000001698	0.219836431	0.608899087	-1.429096697	0.000141902	0.000340334	down	yes	0.29124508	0.27582398	0.092440233	0.588838287	0.69591762	0.541941353	13	7912871	7955961	-	GABRA1	protein_coding	GO:0007214|gamma-aminobutyric acid signaling pathway	GO:0030054|cell junction; GO:0034707|chloride channel complex; GO:0045211|postsynaptic membrane; GO:1902711|GABA-A receptor complex	GO:0004890|GABA-A receptor activity; GO:0022851|GABA-gated chloride ion channel activity; GO:1904315|transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	ko:K05175|GABRA	ko04080|Neuroactive ligand-receptor interaction; ko04723|Retrograde endocannabinoid signaling; ko04727|GABAergic synapse; ko04742|Taste transduction; ko05032|Morphine addiction; ko05033|Nicotine addiction	4141	XP_010013266.1	XP_010013266.1 PREDICTED: gamma-aminobutyric acid receptor subunit alpha-1 [Nestor notabilis]	sp|P19150|GBRA1_CHICK	sp|P19150|GBRA1_CHICK Gamma-aminobutyric acid receptor subunit alpha-1 OS=Gallus gallus GN=GABRA1 PE=2 SV=1	9031.ENSGALP00000002606	Gamma-aminobutyric acid receptor subunit alpha-1 Precursor (GABA(A) receptor subunit alpha-1 [...] 	_	KOG3642	_	PF02931.20|Neur_chan_LBD|Neurotransmitter-gated ion-channel ligand binding domain|ENSGALT00000002609|m.8499:43-249;PF02932.13|Neur_chan_memb|Neurotransmitter-gated ion-channel transmembrane region|ENSGALT00000002609|m.8499:257-341
ENSGALG00000001711	0.494579488	1.121375507	-1.164924378	0.001088508	0.002278662	down	yes	0.336747562	0.769758298	0.377232606	1.393336839	0.916608488	1.054181196	10	2810721	2835077	-	PPCDC	protein_coding	GO:0009108|coenzyme biosynthetic process; GO:0015937|coenzyme A biosynthetic process	GO:0005829|cytosol	GO:0004633|phosphopantothenoylcysteine decarboxylase activity; GO:0042802|identical protein binding	"ko:K01598|PPCDC,coaC"	ko00770|Pantothenate and CoA biosynthesis; ko01100|Metabolic pathways	2409	XP_021263553.1	XP_021263553.1 phosphopantothenoylcysteine decarboxylase isoform X6 [Numida meleagris]	sp|Q96CD2|COAC_HUMAN	sp|Q96CD2|COAC_HUMAN Phosphopantothenoylcysteine decarboxylase OS=Homo sapiens GN=PPCDC PE=1 SV=2	9031.ENSGALP00000002623	annotation not avaliable	COG0452	KOG0672	_	PF02441.16|Flavoprotein|Flavoprotein|ENSGALT00000086692|m.5200:19-149
ENSGALG00000001768	4.906675375	10.3571551	-1.076265042	7.81E-37	1.71E-35	down	yes	4.543636264	4.999073001	5.177316861	10.00511567	11.40013135	9.66621827	13	5570216	6186858	-	TENM2	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0000902|cell morphogenesis; GO:0006351|transcription, DNA-templated; GO:0007157|heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; GO:0007411|axon guidance; GO:0035584|calcium-mediated signaling using intracellular calcium source; GO:0048666|neuron development; GO:0051491|positive regulation of filopodium assembly; GO:0097264|self proteolysis; GO:0098609|cell-cell adhesion"	GO:0005634|nucleus; GO:0005783|endoplasmic reticulum; GO:0005794|Golgi apparatus; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0005911|cell-cell junction; GO:0016605|PML body; GO:0030054|cell junction; GO:0030175|filopodium; GO:0030425|dendrite; GO:0030426|growth cone; GO:0043005|neuron projection; GO:0043197|dendritic spine; GO:0045202|synapse; GO:0045211|postsynaptic membrane	GO:0005102|signaling receptor binding; GO:0005509|calcium ion binding; GO:0042803|protein homodimerization activity; GO:0046982|protein heterodimerization activity; GO:0050839|cell adhesion molecule binding	--	--	9289	XP_015731418.1	XP_015731418.1 PREDICTED: teneurin-2 isoform X4 [Coturnix japonica]	sp|Q9DER5|TEN2_CHICK	sp|Q9DER5|TEN2_CHICK Teneurin-2 OS=Gallus gallus GN=TENM2 PE=1 SV=1	9031.ENSGALP00000002709	Teneurin-2 (Ten-2)(Tenascin-M2)(Ten-m2)(Protein Odd Oz/ten-m homolog 2)(Neurestin); May func [...] 	_	KOG1225;KOG4659	_	PF06484.9|Ten_N|Teneurin Intracellular Region|ENSGALT00000002712|m.8477:10-402;PF15636.3|Tox-GHH|GHH signature containing HNH/Endo VII superfamily nuclease toxin|ENSGALT00000002712|m.8477:2718-2795;PF07974.10|EGF_2|EGF-like domain|ENSGALT00000002712|m.8477:702-727
ENSGALG00000001773	2.476251201	6.677583467	-1.427512925	6.94E-33	1.27E-31	down	yes	2.631922533	2.441105777	2.355725294	6.197355506	6.890862212	6.944532684	28	1679119	1722626	-	RFX2	protein_coding	"GO:0001675|acrosome assembly; GO:0006351|transcription, DNA-templated; GO:0006357|regulation of transcription by RNA polymerase II; GO:0007286|spermatid development; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0060271|cilium assembly; GO:1990830|cellular response to leukemia inhibitory factor"	GO:0005634|nucleus; GO:0005737|cytoplasm	GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity	ko:K09173|RFX1_2_3	--	3820	XP_004948803.1	XP_004948803.1 DNA-binding protein RFX2 isoform X1 [Gallus gallus]	sp|P48378|RFX2_HUMAN	sp|P48378|RFX2_HUMAN DNA-binding protein RFX2 OS=Homo sapiens GN=RFX2 PE=1 SV=2	9031.ENSGALP00000002721	"regulatory factor X, 2 (influences HLA class II expression)"	_	KOG3712	_	PF04589.10|RFX1_trans_act|RFX1 transcription activation region|ENSGALT00000093923|m.9811:16-171;PF02257.12|RFX_DNA_binding|RFX DNA-binding domain|ENSGALT00000093923|m.9811:216-290
ENSGALG00000001801	1.742014516	4.403061207	-1.332765029	2.71E-13	1.58E-12	down	yes	1.649778979	1.792028711	1.784235859	4.114092071	5.25207376	3.843017789	Z	68726465	68758615	+	IFT74	protein_coding	GO:0003334|keratinocyte development; GO:0007219|Notch signaling pathway; GO:0007368|determination of left/right symmetry; GO:0007507|heart development; GO:0033630|positive regulation of cell adhesion mediated by integrin; GO:0035735|intraciliary transport involved in cilium assembly; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0050680|negative regulation of epithelial cell proliferation; GO:0060271|cilium assembly; GO:1905515|non-motile cilium assembly	GO:0005634|nucleus; GO:0005813|centrosome; GO:0005929|cilium; GO:0030992|intraciliary transport particle B; GO:0031410|cytoplasmic vesicle; GO:0031514|motile cilium; GO:0097542|ciliary tip	GO:0003682|chromatin binding; GO:0048487|beta-tubulin binding	ko:K19679|IFT74	--	2474	XP_003643118.1	XP_003643118.1 intraflagellar transport protein 74 homolog [Gallus gallus]	sp|Q96LB3|IFT74_HUMAN	sp|Q96LB3|IFT74_HUMAN Intraflagellar transport protein 74 homolog OS=Homo sapiens GN=IFT74 PE=1 SV=1	9031.ENSGALP00000002778	annotation not avaliable	_	_	NOG128006	_
ENSGALG00000001802	9.040502046	4.476206337	1.012501846	2.67E-25	3.40E-24	up	yes	9.474727949	8.506382157	9.140396031	4.125559738	4.405745378	4.897313895	18	4247802	4258928	+	JMJD6	protein_coding	"GO:0002040|sprouting angiogenesis; GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated; GO:0006397|mRNA processing; GO:0008380|RNA splicing; GO:0018395|peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine; GO:0030154|cell differentiation; GO:0048024|regulation of mRNA splicing, via spliceosome"	GO:0005654|nucleoplasm; GO:0005730|nucleolus	GO:0003727|single-stranded RNA binding; GO:0033746|histone demethylase activity (H3-R2 specific); GO:0033749|histone demethylase activity (H4-R3 specific); GO:0046872|metal ion binding; GO:0070815|peptidyl-lysine 5-dioxygenase activity	ko:K11323|JMJD6	--	4905	XP_011585496.1	XP_011585496.1 PREDICTED: bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 isoform X2 [Aquila chrysaetos canadensis]	sp|Q5ZMK5|JMJD6_CHICK	sp|Q5ZMK5|JMJD6_CHICK Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 OS=Gallus gallus GN=JMJD6 PE=2 SV=1	9031.ENSGALP00000002781	Histone arginine demethylase JMJD6 (EC 1.14.11.-)(JmjC domain-containing protein 6)(Jumonji  [...] 	_	KOG2130	_	"PF02373.19|JmjC|JmjC domain, hydroxylase|ENSGALT00000002784|m.12657:174-288;PF13621.3|Cupin_8|Cupin-like domain|ENSGALT00000002784|m.12657:57-288"
ENSGALG00000001806	3.346790414	1.406655662	1.244593329	1.27E-07	4.50E-07	up	yes	3.339059268	3.766463316	2.934848658	1.380199004	1.378633461	1.461134522	28	1615042	1616784	+	ENSGALG00000001806	protein_coding	GO:0006486|protein glycosylation	GO:0016021|integral component of membrane; GO:0032580|Golgi cisterna membrane	GO:0017060|3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity	ko:K00716|FUT3	ko00601|Glycosphingolipid biosynthesis - lacto and neolacto series; ko01100|Metabolic pathways	1436	XP_025000115.1	"XP_025000115.1 alpha-(1,3)-fucosyltransferase 6 [Gallus gallus]"	sp|Q9GKU6|FUT6_PONPY	"sp|Q9GKU6|FUT6_PONPY Alpha-(1,3)-fucosyltransferase 6 OS=Pongo pygmaeus GN=FUT6 PE=3 SV=1"	9031.ENSGALP00000040459	"Alpha (1,3) fucosyltransferase Fragment "	_	KOG2619	_	"PF00852.16|Glyco_transf_10|Glycosyltransferase family 10 (fucosyltransferase) C-term|ENSGALT00000041254|m.9786:189-360;PF17039.2|Glyco_tran_10_N|Fucosyltransferase, N-terminal|ENSGALT00000041254|m.9786:67-173"
ENSGALG00000001812	0.449881728	1.049615998	-1.204206749	0.000520806	0.001143955	down	yes	0.317279676	0.531725107	0.500640399	1.048523827	1.147272707	0.953051459	28	1582029	1594481	-	ATCAY	protein_coding	GO:0006810|transport; GO:0031175|neuron projection development; GO:0032880|regulation of protein localization; GO:0048311|mitochondrion distribution; GO:2000212|negative regulation of glutamate metabolic process	GO:0005737|cytoplasm; GO:0030054|cell junction; GO:0030424|axon; GO:0030425|dendrite; GO:0031966|mitochondrial membrane; GO:0043005|neuron projection; GO:0045202|synapse	GO:0019894|kinesin binding; GO:0050699|WW domain binding	ko:K18450|ATCAY	--	2325	XP_015155320.1	XP_015155320.1 caytaxin isoform X1 [Gallus gallus]	sp|Q86WG3|ATCAY_HUMAN	sp|Q86WG3|ATCAY_HUMAN Caytaxin OS=Homo sapiens GN=ATCAY PE=1 SV=2	9031.ENSGALP00000002798	"ataxia, cerebellar, Cayman type (caytaxin)"	_	KOG4406	_	PF12496.5|BNIP2|Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2|ENSGALT00000041255|m.9784:61-189;PF13716.3|CRAL_TRIO_2|Divergent CRAL/TRIO domain|ENSGALT00000041255|m.9784:192-328;PF00650.17|CRAL_TRIO|CRAL/TRIO domain|ENSGALT00000041255|m.9784:246-316
ENSGALG00000001824	1.409006374	4.403864221	-1.63716118	3.48E-15	2.35E-14	down	yes	1.221586301	1.413165282	1.592267539	3.81893456	4.745438874	4.647219229	11	1164536	1167744	+	ENSGALG00000001824	protein_coding	--	--	--	--	--	1941	XP_003641962.1	XP_003641962.1 uncharacterized protein LOC100857820 [Gallus gallus]	_	_	9031.ENSGALP00000002815	hypothetical protein LOC769576	COG1028	KOG1611	_	PF00106.22|adh_short|short chain dehydrogenase|ENSGALT00000002818|m.6270:8-217;PF13561.3|adh_short_C2|Enoyl-(Acyl carrier protein) reductase|ENSGALT00000002818|m.6270:13-224;PF08659.7|KR|KR domain|ENSGALT00000002818|m.6270:9-131
ENSGALG00000001840	0.367750629	0.929315998	-1.314176422	2.96E-06	8.90E-06	down	yes	0.411176734	0.443345792	0.248729362	0.864295378	0.94701592	0.976636695	Z	68766291	68802701	+	TEK	protein_coding	GO:0001525|angiogenesis; GO:0001934|positive regulation of protein phosphorylation; GO:0001935|endothelial cell proliferation; GO:0002040|sprouting angiogenesis; GO:0007169|transmembrane receptor protein tyrosine kinase signaling pathway; GO:0007507|heart development; GO:0010595|positive regulation of endothelial cell migration; GO:0014068|positive regulation of phosphatidylinositol 3-kinase signaling; GO:0016525|negative regulation of angiogenesis; GO:0018108|peptidyl-tyrosine phosphorylation; GO:0032878|regulation of establishment or maintenance of cell polarity; GO:0034446|substrate adhesion-dependent cell spreading; GO:0043552|positive regulation of phosphatidylinositol 3-kinase activity; GO:0045766|positive regulation of angiogenesis; GO:0046777|protein autophosphorylation; GO:0048014|Tie signaling pathway; GO:0051259|protein complex oligomerization; GO:0051894|positive regulation of focal adhesion assembly; GO:0051897|positive regulation of protein kinase B signaling; GO:0060347|heart trabecula formation; GO:0070374|positive regulation of ERK1 and ERK2 cascade; GO:1902533|positive regulation of intracellular signal transduction; GO:2000251|positive regulation of actin cytoskeleton reorganization; GO:2000352|negative regulation of endothelial cell apoptotic process	GO:0001725|stress fiber; GO:0005576|extracellular region; GO:0005737|cytoplasm; GO:0005815|microtubule organizing center; GO:0005884|actin filament; GO:0005887|integral component of plasma membrane; GO:0005902|microvillus; GO:0005911|cell-cell junction; GO:0005925|focal adhesion; GO:0009925|basal plasma membrane; GO:0009986|cell surface; GO:0016324|apical plasma membrane; GO:0045121|membrane raft	GO:0004713|protein tyrosine kinase activity; GO:0004714|transmembrane receptor protein tyrosine kinase activity; GO:0005524|ATP binding	"ko:K05121|TEK,TIE2,CD202"	ko04014|Ras signaling pathway; ko04015|Rap1 signaling pathway; ko04066|HIF-1 signaling pathway; ko04151|PI3K-Akt signaling pathway; ko05323|Rheumatoid arthritis	4357	XP_004949637.1	XP_004949637.1 angiopoietin-1 receptor [Gallus gallus]	sp|Q06807|TIE2_BOVIN	sp|Q06807|TIE2_BOVIN Angiopoietin-1 receptor OS=Bos taurus GN=TEK PE=2 SV=1	9031.ENSGALP00000002841	"TEK tyrosine kinase, endothelial (venous malformations, multiple cutaneous and mucosal)"	COG0515	KOG0200	_	PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000102096|m.11877:828-1094;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000102096|m.11877:831-1093;PF10430.6|Ig_Tie2_1|Tie-2 Ig-like domain 1|ENSGALT00000102096|m.11877:24-118;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000102096|m.11877:451-527;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000102096|m.11877:544-629;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000102096|m.11877:643-725;PF12661.4|hEGF|Human growth factor-like EGF|ENSGALT00000102096|m.11877:239-251
ENSGALG00000001844	3.508044776	1.615214189	1.114143979	0.000180768	0.000426299	up	yes	4.107323204	2.796386302	3.620424823	1.56703307	1.902905255	1.375704244	19	4300257	4302289	-	ALKBH4	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated; GO:0006482|protein demethylation; GO:0031032|actomyosin structure organization; GO:0036090|cleavage furrow ingression"	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0030496|midbody; GO:0070938|contractile ring	GO:0003779|actin binding; GO:0016706|2-oxoglutarate-dependent dioxygenase activity; GO:0032451|demethylase activity; GO:0046872|metal ion binding	ko:K10766|ALKBH4	--	898	XP_415758.3	XP_415758.3 alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 [Gallus gallus]	sp|Q9NXW9|ALKB4_HUMAN	sp|Q9NXW9|ALKB4_HUMAN Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 OS=Homo sapiens GN=ALKBH4 PE=1 SV=1	_	_	_	_	_	_
ENSGALG00000001862	0.391170893	1.297133784	-1.704117968	3.41E-06	1.02E-05	down	yes	0.156295407	0.630277605	0.386939667	1.278687594	1.151290634	1.461423125	18	4293769	4305245	+	ST6GALNAC1	protein_coding	GO:0001574|ganglioside biosynthetic process; GO:0009311|oligosaccharide metabolic process; GO:0009312|oligosaccharide biosynthetic process; GO:0018279|protein N-linked glycosylation via asparagine	GO:0000139|Golgi membrane; GO:0016021|integral component of membrane	"GO:0001665|alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity"	"ko:K03479|SIAT7A,ST6GalNAcI"	ko00512|Mucin type O-glycan biosynthesis; ko01100|Metabolic pathways	2697	NP_990571.1	"NP_990571.1 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 [Gallus gallus]"	sp|Q92183|SIA7A_CHICK	"sp|Q92183|SIA7A_CHICK Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 OS=Gallus gallus GN=ST6GALNAC1 PE=2 SV=1"	9031.ENSGALP00000002878	"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3)(GalNAc alpha-2,6-s [...] "	_	KOG2692	_	PF00777.15|Glyco_transf_29|Glycosyltransferase family 29 (sialyltransferase)|ENSGALT00000002882|m.12659:288-574
ENSGALG00000001882	0.688218891	2.040205617	-1.554017309	3.72E-09	1.53E-08	down	yes	0.913220315	0.429537992	0.721898368	1.685124592	2.357861371	2.077630888	21	2563494	2569802	+	TNFRSF18	protein_coding	GO:0002687|positive regulation of leukocyte migration; GO:0006954|inflammatory response; GO:0006955|immune response; GO:0007165|signal transduction; GO:0007275|multicellular organism development; GO:0032496|response to lipopolysaccharide; GO:0033209|tumor necrosis factor-mediated signaling pathway; GO:0042127|regulation of cell population proliferation; GO:0042531|positive regulation of tyrosine phosphorylation of STAT protein; GO:0042981|regulation of apoptotic process; GO:0043066|negative regulation of apoptotic process; GO:0045589|regulation of regulatory T cell differentiation; GO:0045785|positive regulation of cell adhesion; GO:0097190|apoptotic signaling pathway	GO:0005576|extracellular region; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0009897|external side of plasma membrane	GO:0005031|tumor necrosis factor-activated receptor activity	"ko:K05154|TNFRSF18,GITR,CD357"	ko04060|Cytokine-cytokine receptor interaction	3058	NP_001026045.1	NP_001026045.1 tumor necrosis factor receptor superfamily member 18 precursor [Gallus gallus]	sp|Q9Y5U5|TNR18_HUMAN	sp|Q9Y5U5|TNR18_HUMAN Tumor necrosis factor receptor superfamily member 18 OS=Homo sapiens GN=TNFRSF18 PE=1 SV=1	9031.ENSGALP00000002913	"tumor necrosis factor receptor superfamily, member 18 "	_	_	NOG46178	_
ENSGALG00000001883	0.297674178	5.035157054	-4.035423909	1.46E-43	4.21E-42	down	yes	0.404538112	0.315145676	0.173338744	5.93448484	4.409816565	4.761169758	18	4308786	4315058	+	ST6GALNAC2	protein_coding	GO:0009311|oligosaccharide metabolic process; GO:0018279|protein N-linked glycosylation via asparagine; GO:0097503|sialylation	GO:0000139|Golgi membrane; GO:0016021|integral component of membrane	GO:0008373|sialyltransferase activity	"ko:K06616|SIAT7B,ST6GalNAcII"	--	2084	NP_990564.1	"NP_990564.1 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 [Gallus gallus]"	sp|Q92184|SIA7B_CHICK	"sp|Q92184|SIA7B_CHICK Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 OS=Gallus gallus GN=ST6GALNAC2 PE=2 SV=1"	9031.ENSGALP00000002914	"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (EC 2.4.99.-)(GalNAc alpha-2,6-s [...] "	_	KOG2692	_	PF00777.15|Glyco_transf_29|Glycosyltransferase family 29 (sialyltransferase)|ENSGALT00000002918|m.12661:121-403
ENSGALG00000001916	0.169867779	1.001569126	-2.491586238	3.47E-18	2.91E-17	down	yes	0.17084656	0.147370407	0.191386369	0.948833508	1.120853624	0.935020247	13	4953827	5426056	+	SLIT3	protein_coding	GO:0007411|axon guidance; GO:0008285|negative regulation of cell population proliferation; GO:0009887|animal organ morphogenesis; GO:0010629|negative regulation of gene expression; GO:0030308|negative regulation of cell growth; GO:0032870|cellular response to hormone stimulus; GO:0035385|Roundabout signaling pathway; GO:0048846|axon extension involved in axon guidance; GO:0050919|negative chemotaxis; GO:0051414|response to cortisol; GO:0061364|apoptotic process involved in luteolysis; GO:0070100|negative regulation of chemokine-mediated signaling pathway	GO:0005615|extracellular space	GO:0005102|signaling receptor binding; GO:0005509|calcium ion binding; GO:0048495|Roundabout binding	ko:K06850|SLIT3	ko04360|Axon guidance	4926	XP_021265915.1	XP_021265915.1 slit homolog 3 protein isoform X1 [Numida meleagris]	sp|Q9WVB4|SLIT3_MOUSE	sp|Q9WVB4|SLIT3_MOUSE Slit homolog 3 protein OS=Mus musculus GN=Slit3 PE=2 SV=2	9031.ENSGALP00000002963	Slit3 protein Fragment 	COG4886	KOG4237	_	PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000093565|m.8446:179-238;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000093565|m.8446:227-286;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000093565|m.8446:276-332;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000093565|m.8446:429-484;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000093565|m.8446:449-508;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000093565|m.8446:501-555;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000093565|m.8446:652-710;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000093565|m.8446:699-758;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000093565|m.8446:740-781;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000093565|m.8446:871-928;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000093565|m.8446:917-976;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000093565|m.8446:188-270;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000093565|m.8446:245-332;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000093565|m.8446:438-553;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000093565|m.8446:669-780;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000093565|m.8446:894-971;PF00008.24|EGF|EGF-like domain|ENSGALT00000093565|m.8446:1037-1067;PF00008.24|EGF|EGF-like domain|ENSGALT00000093565|m.8446:1076-1109;PF00008.24|EGF|EGF-like domain|ENSGALT00000093565|m.8446:1117-1146;PF00008.24|EGF|EGF-like domain|ENSGALT00000093565|m.8446:1195-1224;PF01462.15|LRRNT|Leucine rich repeat N-terminal domain|ENSGALT00000093565|m.8446:150-177;PF01462.15|LRRNT|Leucine rich repeat N-terminal domain|ENSGALT00000093565|m.8446:397-423;PF01462.15|LRRNT|Leucine rich repeat N-terminal domain|ENSGALT00000093565|m.8446:622-648;PF02210.21|Laminin_G_2|Laminin G domain|ENSGALT00000093565|m.8446:1304-1430;PF00054.20|Laminin_G_1|Laminin G domain|ENSGALT00000093565|m.8446:1303-1433;PF12661.4|hEGF|Human growth factor-like EGF|ENSGALT00000093565|m.8446:1099-1110;PF12661.4|hEGF|Human growth factor-like EGF|ENSGALT00000093565|m.8446:1136-1148;PF12661.4|hEGF|Human growth factor-like EGF|ENSGALT00000093565|m.8446:1177-1188;PF12661.4|hEGF|Human growth factor-like EGF|ENSGALT00000093565|m.8446:1214-1226;PF12661.4|hEGF|Human growth factor-like EGF|ENSGALT00000093565|m.8446:1469-1481;PF01463.21|LRRCT|Leucine rich repeat C-terminal domain|ENSGALT00000093565|m.8446:356-381;PF01463.21|LRRCT|Leucine rich repeat C-terminal domain|ENSGALT00000093565|m.8446:579-603;PF01463.21|LRRCT|Leucine rich repeat C-terminal domain|ENSGALT00000093565|m.8446:804-829;PF01463.21|LRRCT|Leucine rich repeat C-terminal domain|ENSGALT00000093565|m.8446:999-1023
ENSGALG00000001918	3.351920594	1.294050177	1.366286267	1.14E-13	6.86E-13	up	yes	3.570443409	2.776509919	3.708808454	1.187008932	1.433492732	1.261648867	Z	8525124	8538233	+	DNAJB5	protein_coding	GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006457|protein folding; GO:0006986|response to unfolded protein	GO:0005634|nucleus; GO:0005829|cytosol	GO:0051082|unfolded protein binding; GO:0051087|chaperone binding	ko:K09511|DNAJB5	--	2749	XP_010723544.1	XP_010723544.1 PREDICTED: dnaJ homolog subfamily B member 5 isoform X2 [Meleagris gallopavo]	sp|O89114|DNJB5_MOUSE	sp|O89114|DNJB5_MOUSE DnaJ homolog subfamily B member 5 OS=Mus musculus GN=Dnajb5 PE=2 SV=1	9031.ENSGALP00000002967	"DnaJ (Hsp40) homolog, subfamily B, member 5"	COG0484	KOG0714	_	PF01556.15|DnaJ_C|DnaJ C terminal domain|ENSGALT00000101250|m.10472:183-341;PF00226.28|DnaJ|DnaJ domain|ENSGALT00000101250|m.10472:16-77
ENSGALG00000001968	0.383183364	0.117281457	1.627180026	0.00186603	0.003762891	up	yes	0.557845987	0.347041471	0.244662636	0.178039915	0.066856378	0.106948078	26	3808445	3837071	-	SYT6	protein_coding	GO:0006906|vesicle fusion; GO:0017158|regulation of calcium ion-dependent exocytosis; GO:0048791|calcium ion-regulated exocytosis of neurotransmitter; GO:0060478|acrosomal vesicle exocytosis	GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0019898|extrinsic component of membrane; GO:0030054|cell junction; GO:0030672|synaptic vesicle membrane; GO:0097038|perinuclear endoplasmic reticulum	GO:0001786|phosphatidylserine binding; GO:0005509|calcium ion binding; GO:0019905|syntaxin binding; GO:0030276|clathrin binding; GO:0042803|protein homodimerization activity; GO:0048306|calcium-dependent protein binding	ko:K19906|SYT6	--	3117	XP_425830.4	XP_425830.4 synaptotagmin-6 [Gallus gallus]	sp|Q5T7P8|SYT6_HUMAN	sp|Q5T7P8|SYT6_HUMAN Synaptotagmin-6 OS=Homo sapiens GN=SYT6 PE=1 SV=3	9031.ENSGALP00000003054	synaptotagmin VI	COG5038	KOG1028	_	PF00168.27|C2|C2 domain|ENSGALT00000003058|m.8158:131-227;PF00168.27|C2|C2 domain|ENSGALT00000003058|m.8158:262-366
ENSGALG00000001998	6.905666941	13.95372316	-1.013743364	1.24E-15	8.71E-15	down	yes	6.372773615	7.021836464	7.322390745	14.8245683	12.92589475	14.11070643	28	2942189	2947196	-	R3HDM4	protein_coding	--	GO:0005634|nucleus	GO:0003676|nucleic acid binding	--	--	1480	XP_021234147.1	XP_021234147.1 R3H domain-containing protein 4 [Numida meleagris]	sp|Q2KIL7|R3HD4_BOVIN	sp|Q2KIL7|R3HD4_BOVIN R3H domain-containing protein 4 OS=Bos taurus GN=R3HDM4 PE=2 SV=1	_	_	_	_	_	PF13902.3|R3H-assoc|R3H-associated N-terminal domain|ENSGALT00000003109|m.10053:66-202;PF01424.19|R3H|R3H domain|ENSGALT00000003109|m.10053:212-266
ENSGALG00000002016	3.313870162	14.30680118	-2.106773253	1.07E-75	7.75E-74	down	yes	3.418772998	2.91342782	3.609409667	13.79028545	15.89917928	13.23093881	12	1720584	1784240	+	PRKCD	protein_coding	GO:0006915|apoptotic process; GO:0007049|cell cycle; GO:0018105|peptidyl-serine phosphorylation; GO:0030837|negative regulation of actin filament polymerization; GO:0032930|positive regulation of superoxide anion generation; GO:0034351|negative regulation of glial cell apoptotic process; GO:0035556|intracellular signal transduction; GO:0042742|defense response to bacterium; GO:0051490|negative regulation of filopodium assembly; GO:0090331|negative regulation of platelet aggregation; GO:1904385|cellular response to angiotensin	GO:0005622|intracellular; GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005739|mitochondrion; GO:0005783|endoplasmic reticulum; GO:0016020|membrane; GO:0048471|perinuclear region of cytoplasm	GO:0004674|protein serine/threonine kinase activity; GO:0004697|protein kinase C activity; GO:0004715|non-membrane spanning protein tyrosine kinase activity; GO:0005524|ATP binding; GO:0046872|metal ion binding	ko:K06068|PRKCD	ko04062|Chemokine signaling pathway; ko04140|Autophagy - animal; ko04270|Vascular smooth muscle contraction; ko04621|NOD-like receptor signaling pathway; ko04666|Fc gamma R-mediated phagocytosis; ko04722|Neurotrophin signaling pathway; ko04750|Inflammatory mediator regulation of TRP channels; ko04912|GnRH signaling pathway; ko04915|Estrogen signaling pathway; ko04930|Type II diabetes mellitus; ko04931|Insulin resistance; ko04933|AGE-RAGE signaling pathway in diabetic complications	2777	XP_015148252.1	XP_015148252.1 protein kinase C delta type isoform X1 [Gallus gallus]	sp|Q5PU49|KPCD_CANLF	sp|Q5PU49|KPCD_CANLF Protein kinase C delta type OS=Canis lupus familiaris GN=PRKCD PE=2 SV=1	9031.ENSGALP00000003132	"protein kinase C, delta "	COG0515	KOG0694	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000091006|m.7139:360-612;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000091006|m.7139:359-600;PF00130.19|C1_1|Phorbol esters/diacylglycerol binding domain (C1 domain)|ENSGALT00000091006|m.7139:157-207;PF00130.19|C1_1|Phorbol esters/diacylglycerol binding domain (C1 domain)|ENSGALT00000091006|m.7139:229-280;PF00433.21|Pkinase_C|Protein kinase C terminal domain|ENSGALT00000091006|m.7139:633-674
ENSGALG00000002023	3.02768569	1.471182503	1.036223189	1.33E-11	6.76E-11	up	yes	3.244726246	3.16456689	2.673763933	1.350991385	1.319596542	1.742959582	Z	8577948	8591196	-	PIGO	protein_coding	GO:0006506|GPI anchor biosynthetic process	GO:0005789|endoplasmic reticulum membrane; GO:0016020|membrane; GO:0016021|integral component of membrane	GO:0051377|mannose-ethanolamine phosphotransferase activity	ko:K05288|PIGO	ko00563|Glycosylphosphatidylinositol (GPI)-anchor biosynthesis; ko01100|Metabolic pathways	5164	POI32660.1	POI32660.1 hypothetical protein CIB84_003587 [Bambusicola thoracicus]	sp|Q8TEQ8|PIGO_HUMAN	sp|Q8TEQ8|PIGO_HUMAN GPI ethanolamine phosphate transferase 3 OS=Homo sapiens GN=PIGO PE=1 SV=3	9031.ENSGALP00000003142	"phosphatidylinositol glycan anchor biosynthesis, class O"	COG1524	KOG2126	_	PF01663.19|Phosphodiest|Type I phosphodiesterase / nucleotide pyrophosphatase|ENSGALT00000003147|m.10476:209-281
ENSGALG00000002028	5.424753199	2.68614621	1.011315787	1.06E-07	3.75E-07	up	yes	4.922375539	5.833560599	5.51832346	2.445433677	3.354831072	2.258173881	14	15029907	15042718	+	GPRC5B	protein_coding	GO:0043123|positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0045666|positive regulation of neuron differentiation; GO:0050729|positive regulation of inflammatory response; GO:0060907|positive regulation of macrophage cytokine production; GO:0061098|positive regulation of protein tyrosine kinase activity; GO:0090263|positive regulation of canonical Wnt signaling pathway	GO:0005615|extracellular space; GO:0005634|nucleus; GO:0005730|nucleolus; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0009986|cell surface; GO:0016021|integral component of membrane; GO:0030659|cytoplasmic vesicle membrane; GO:0043231|intracellular membrane-bounded organelle; GO:0070062|extracellular exosome	GO:0001664|G protein-coupled receptor binding; GO:0004930|G protein-coupled receptor activity; GO:0019901|protein kinase binding; GO:0030295|protein kinase activator activity	ko:K04619|GPRC5B	--	1468	XP_004945521.1	XP_004945521.1 G-protein coupled receptor family C group 5 member B isoform X2 [Gallus gallus]	sp|Q9NZH0|GPC5B_HUMAN	sp|Q9NZH0|GPC5B_HUMAN G-protein coupled receptor family C group 5 member B OS=Homo sapiens GN=GPRC5B PE=2 SV=2	_	_	_	_	_	PF00003.19|7tm_3|7 transmembrane sweet-taste receptor of 3 GCPR|ENSGALT00000091140|m.10116:110-331
ENSGALG00000002042	11.82355574	5.248288135	1.170218535	9.66E-20	8.92E-19	up	yes	10.94654118	13.47223695	11.05188908	4.999847698	6.07306972	4.671946986	14	15091186	15101366	+	ENSGALG00000002042	protein_coding	--	GO:0005730|nucleolus	GO:0003723|RNA binding	--	--	2426	XP_004945520.1	XP_004945520.1 lysine-rich nucleolar protein 1 isoform X2 [Gallus gallus]	sp|Q1ED39|KNOP1_HUMAN	sp|Q1ED39|KNOP1_HUMAN Lysine-rich nucleolar protein 1 OS=Homo sapiens GN=KNOP1 PE=1 SV=1	9031.ENSGALP00000029151	similar to TSG118.1 protein	_	_	NOG134036	PF15477.3|SMAP|Small acidic protein family|ENSGALT00000029798|m.10119:533-606
ENSGALG00000002111	1.017361197	5.424402493	-2.403177931	9.55E-23	1.05E-21	down	yes	1.122451685	0.634872253	1.294759654	6.140113068	4.857813754	5.275280658	14	13715895	13723537	+	ENSGALG00000002111	protein_coding	GO:0006605|protein targeting; GO:0006974|cellular response to DNA damage stimulus; GO:0008286|insulin receptor signaling pathway; GO:0010838|positive regulation of keratinocyte proliferation; GO:0050821|protein stabilization; GO:0061178|regulation of insulin secretion involved in cellular response to glucose stimulus; GO:1902808|positive regulation of cell cycle G1/S phase transition; GO:1904659|glucose transmembrane transport	GO:0005737|cytoplasm; GO:0070062|extracellular exosome	GO:0019905|syntaxin binding	--	--	1643	XP_003642201.3	XP_003642201.3 syntaxin-binding protein 4 isoform X1 [Gallus gallus]	sp|Q9WV89|STXB4_MOUSE	sp|Q9WV89|STXB4_MOUSE Syntaxin-binding protein 4 OS=Mus musculus GN=Stxbp4 PE=1 SV=1	_	_	_	_	_	_
ENSGALG00000002123	0.247666152	0.688502443	-1.438762127	0.002725835	0.005338995	down	yes	0.093839874	0.309615646	0.339542937	0.670656271	0.556699906	0.83815115	23	4171808	4182985	+	OSCP1	protein_coding	GO:0006810|transport; GO:1903955|positive regulation of protein targeting to mitochondrion	GO:0009925|basal plasma membrane	--	--	--	2246	XP_024998895.1	XP_024998895.1 protein OSCP1 isoform X1 [Gallus gallus]	sp|Q8WVF1|OSCP1_HUMAN	sp|Q8WVF1|OSCP1_HUMAN Protein OSCP1 OS=Homo sapiens GN=OSCP1 PE=1 SV=4	9031.ENSGALP00000003312	chromosome 1 open reading frame 102	_	KOG4033	_	PF10188.6|Oscp1|Organic solute transport protein 1|ENSGALT00000003317|m.5561:17-199;PF00312.19|Ribosomal_S15|Ribosomal protein S15|ENSGALT00000003317|m.5562:1-39
ENSGALG00000002132	0.31533809	1.116415186	-1.791727045	1.81E-05	4.93E-05	down	yes	0.242676288	0.333619623	0.369718358	1.095386954	1.271703002	0.982155603	13	4271443	4451078	-	KCNIP1	protein_coding	GO:1901379|regulation of potassium ion transmembrane transport	GO:0005737|cytoplasm; GO:0008076|voltage-gated potassium channel complex; GO:0030425|dendrite; GO:0031234|extrinsic component of cytoplasmic side of plasma membrane	GO:0005244|voltage-gated ion channel activity; GO:0005267|potassium channel activity; GO:0005509|calcium ion binding; GO:0015459|potassium channel regulator activity	--	--	1370	XP_003210306.1	XP_003210306.1 PREDICTED: Kv channel-interacting protein 1 isoform X5 [Meleagris gallopavo]	sp|Q9JJ57|KCIP1_MOUSE	sp|Q9JJ57|KCIP1_MOUSE Kv channel-interacting protein 1 OS=Mus musculus GN=Kcnip1 PE=1 SV=2	9031.ENSGALP00000003327	annotation not avaliable	COG5126	KOG0044	_	PF13499.3|EF-hand_7|EF-hand domain pair|ENSGALT00000089580|m.8436:125-199;PF00036.29|EF-hand_1|EF hand|ENSGALT00000089580|m.8436:127-153;PF13833.3|EF-hand_8|EF-hand domain pair|ENSGALT00000089580|m.8436:67-112;PF13833.3|EF-hand_8|EF-hand domain pair|ENSGALT00000089580|m.8436:108-149;PF13833.3|EF-hand_8|EF-hand domain pair|ENSGALT00000089580|m.8436:175-197;PF13202.3|EF-hand_5|EF hand|ENSGALT00000089580|m.8436:130-149;PF13202.3|EF-hand_5|EF hand|ENSGALT00000089580|m.8436:178-196
ENSGALG00000002150	0.584608664	1.234993563	-1.066125894	5.73E-05	0.000145209	down	yes	0.469020376	0.560043154	0.724762461	0.962755499	1.256071861	1.486153331	10	1793936	1820488	-	CPEB1	protein_coding	GO:0006397|mRNA processing; GO:0008285|negative regulation of cell population proliferation; GO:0010976|positive regulation of neuron projection development; GO:0030335|positive regulation of cell migration; GO:0032869|cellular response to insulin stimulus; GO:0045727|positive regulation of translation; GO:0051028|mRNA transport; GO:0051770|positive regulation of nitric-oxide synthase biosynthetic process; GO:0071222|cellular response to lipopolysaccharide; GO:0071230|cellular response to amino acid stimulus; GO:0071456|cellular response to hypoxia; GO:2000766|negative regulation of cytoplasmic translation	GO:0000932|P-body; GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005813|centrosome; GO:0014069|postsynaptic density; GO:0030054|cell junction; GO:0030425|dendrite; GO:0030426|growth cone; GO:0043005|neuron projection; GO:0043025|neuronal cell body; GO:0045202|synapse; GO:0045211|postsynaptic membrane; GO:0048471|perinuclear region of cytoplasm; GO:1990124|messenger ribonucleoprotein complex	"GO:0000900|translation repressor activity, mRNA regulatory element binding; GO:0003730|mRNA 3'-UTR binding; GO:0008135|translation factor activity, RNA binding; GO:0035925|mRNA 3'-UTR AU-rich region binding; GO:0043022|ribosome binding; GO:0046872|metal ion binding"	"ko:K02602|CPEB,ORB"	ko04114|Oocyte meiosis; ko04320|Dorso-ventral axis formation; ko04914|Progesterone-mediated oocyte maturation	3932	NP_001280148.1	NP_001280148.1 cytoplasmic polyadenylation element-binding protein 1 [Gallus gallus]	sp|Q9BZB8|CPEB1_HUMAN	sp|Q9BZB8|CPEB1_HUMAN Cytoplasmic polyadenylation element-binding protein 1 OS=Homo sapiens GN=CPEB1 PE=1 SV=1	_	_	_	_	_	PF16368.2|CEBP1_N|Cytoplasmic polyadenylation element-binding protein 1 N-terminus|ENSGALT00000003371|m.5128:1-307;PF16367.2|RRM_7|RNA recognition motif|ENSGALT00000003371|m.5128:310-405;PF16366.2|CEBP_ZZ|Cytoplasmic polyadenylation element-binding protein ZZ domain|ENSGALT00000003371|m.5128:497-554
ENSGALG00000002200	0.443027566	0.991869604	-1.145024007	0.001723427	0.003497508	down	yes	0.583382297	0.479064776	0.266635624	0.860197721	1.116711741	0.998699349	14	15208575	15219030	+	ACSM3	protein_coding	GO:0006633|fatty acid biosynthetic process; GO:0006635|fatty acid beta-oxidation; GO:0006637|acyl-CoA metabolic process	GO:0005739|mitochondrion; GO:0005759|mitochondrial matrix	GO:0003996|acyl-CoA ligase activity; GO:0004321|fatty-acyl-CoA synthase activity; GO:0005524|ATP binding; GO:0015645|fatty acid ligase activity; GO:0046872|metal ion binding; GO:0047760|butyrate-CoA ligase activity	ko:K01896|ACSM	ko00650|Butanoate metabolism; ko01100|Metabolic pathways	2024	XP_015150306.1	"XP_015150306.1 acyl-coenzyme A synthetase ACSM3, mitochondrial isoform X2 [Gallus gallus]"	sp|Q3UNX5|ACSM3_MOUSE	"sp|Q3UNX5|ACSM3_MOUSE Acyl-coenzyme A synthetase ACSM3, mitochondrial OS=Mus musculus GN=Acsm3 PE=1 SV=2"	9031.ENSGALP00000003439	acyl-CoA synthetase medium-chain family member 3	COG0365	KOG1175	_	PF00501.25|AMP-binding|AMP-binding enzyme|ENSGALT00000097515|m.10124:69-244;PF00501.25|AMP-binding|AMP-binding enzyme|ENSGALT00000097515|m.10124:258-397;PF13193.3|AMP-binding_C|AMP-binding enzyme C-terminal domain|ENSGALT00000097515|m.10124:406-486
ENSGALG00000002203	2.768701102	1.314026863	1.069478263	7.45E-05	0.00018592	up	yes	2.901092311	2.366380285	3.038630709	1.60957991	1.333819259	0.998681419	13	3919090	4012490	-	FGF18	protein_coding	GO:0000165|MAPK cascade; GO:0001525|angiogenesis; GO:0001957|intramembranous ossification; GO:0001958|endochondral ossification; GO:0002063|chondrocyte development; GO:0007165|signal transduction; GO:0007267|cell-cell signaling; GO:0008284|positive regulation of cell population proliferation; GO:0008543|fibroblast growth factor receptor signaling pathway; GO:0009653|anatomical structure morphogenesis; GO:0014066|regulation of phosphatidylinositol 3-kinase signaling; GO:0030324|lung development; GO:0030949|positive regulation of vascular endothelial growth factor receptor signaling pathway; GO:0032332|positive regulation of chondrocyte differentiation; GO:0038111|interleukin-7-mediated signaling pathway; GO:0043406|positive regulation of MAP kinase activity; GO:0048015|phosphatidylinositol-mediated signaling; GO:0070374|positive regulation of ERK1 and ERK2 cascade; GO:2000546|positive regulation of endothelial cell chemotaxis to fibroblast growth factor	GO:0005576|extracellular region; GO:0005615|extracellular space; GO:0005730|nucleolus	"GO:0004713|protein tyrosine kinase activity; GO:0005088|Ras guanyl-nucleotide exchange factor activity; GO:0005105|type 1 fibroblast growth factor receptor binding; GO:0005111|type 2 fibroblast growth factor receptor binding; GO:0008083|growth factor activity; GO:0016303|1-phosphatidylinositol-3-kinase activity; GO:0046934|phosphatidylinositol-4,5-bisphosphate 3-kinase activity"	ko:K04358|FGF	ko04010|MAPK signaling pathway; ko04014|Ras signaling pathway; ko04015|Rap1 signaling pathway; ko04151|PI3K-Akt signaling pathway; ko04810|Regulation of actin cytoskeleton; ko05200|Pathways in cancer; ko05218|Melanoma; ko05224|Breast cancer	1453	NP_990045.1	NP_990045.1 fibroblast growth factor 18 precursor [Gallus gallus]	sp|O76093|FGF18_HUMAN	sp|O76093|FGF18_HUMAN Fibroblast growth factor 18 OS=Homo sapiens GN=FGF18 PE=1 SV=1	9031.ENSGALP00000003444	fibroblast growth factor 18 	_	KOG3885	_	PF00167.15|FGF|Fibroblast growth factor|ENSGALT00000055066|m.8423:94-216
ENSGALG00000002205	52.11065801	124.6221095	-1.257748601	1.68E-58	7.89E-57	down	yes	57.61460507	49.02326034	49.69410862	134.4578875	124.8538062	114.5546348	15	1850942	1898896	-	FBRSL1	protein_coding	"GO:0001764|neuron migration; GO:0006351|transcription, DNA-templated; GO:0010592|positive regulation of lamellipodium assembly; GO:0031532|actin cytoskeleton reorganization; GO:0035022|positive regulation of Rac protein signal transduction; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0048675|axon extension; GO:0051571|positive regulation of histone H3-K4 methylation; GO:0060013|righting reflex; GO:0097484|dendrite extension; GO:0098582|innate vocalization behavior; GO:2000620|positive regulation of histone H4-K16 acetylation"	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005856|cytoskeleton; GO:0030426|growth cone	GO:0003682|chromatin binding	--	--	3000	XP_015733110.1	XP_015733110.1 PREDICTED: fibrosin-1-like protein isoform X2 [Coturnix japonica]	sp|A0A087WPF7|AUTS2_MOUSE	sp|A0A087WPF7|AUTS2_MOUSE Autism susceptibility gene 2 protein homolog OS=Mus musculus GN=Auts2 PE=1 SV=2	9031.ENSGALP00000003447	fibrosin-like 1	_	_	NOG44952	PF15336.3|Auts2|Autism susceptibility gene 2 protein|ENSGALT00000003452|m.10384:388-602
ENSGALG00000002225	4.474533491	10.58126896	-1.239845632	0.004079246	0.007758466	down	yes	4.940674395	3.425292922	5.057633156	12.38062981	13.8628946	5.500282477	19	4627665	4651317	+	RFFL	protein_coding	GO:0006511|ubiquitin-dependent protein catabolic process; GO:0006915|apoptotic process; GO:0010762|regulation of fibroblast migration; GO:0010804|negative regulation of tumor necrosis factor-mediated signaling pathway; GO:0032006|regulation of TOR signaling; GO:0043161|proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0070936|protein K48-linked ubiquitination; GO:1901797|negative regulation of signal transduction by p53 class mediator; GO:1902042|negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; GO:2001271|negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis	GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0010008|endosome membrane; GO:0016020|membrane; GO:0055038|recycling endosome membrane	GO:0002020|protease binding; GO:0002039|p53 binding; GO:0019901|protein kinase binding; GO:0031625|ubiquitin protein ligase binding; GO:0046872|metal ion binding; GO:0061630|ubiquitin protein ligase activity	ko:K20804|RNF34	--	3501	NP_001025882.1	NP_001025882.1 E3 ubiquitin-protein ligase rififylin [Gallus gallus]	sp|Q8WZ73|RFFL_HUMAN	sp|Q8WZ73|RFFL_HUMAN E3 ubiquitin-protein ligase rififylin OS=Homo sapiens GN=RFFL PE=1 SV=1	9031.ENSGALP00000003479	rififylin 	_	KOG4275	_	"PF13920.3|zf-C3HC4_3|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000095572|m.13736:309-352"
ENSGALG00000002260	2.929633221	7.791633363	-1.40814004	2.86E-11	1.41E-10	down	yes	4.049949004	2.449011239	2.28993942	8.590612332	7.761008386	7.023279372	12	2264031	2268470	-	CISH	protein_coding	GO:0006469|negative regulation of protein kinase activity; GO:0016567|protein ubiquitination; GO:0019221|cytokine-mediated signaling pathway; GO:0035556|intracellular signal transduction; GO:0040008|regulation of growth; GO:0046426|negative regulation of receptor signaling pathway via JAK-STAT; GO:0046627|negative regulation of insulin receptor signaling pathway	GO:0005737|cytoplasm	GO:0004860|protein kinase inhibitor activity	ko:K04701|CISH	ko04630|Jak-STAT signaling pathway; ko04917|Prolactin signaling pathway	1262	XP_015729992.1	XP_015729992.1 PREDICTED: cytokine-inducible SH2-containing protein [Coturnix japonica]	sp|Q9PW70|CISH_CHICK	sp|Q9PW70|CISH_CHICK Cytokine-inducible SH2-containing protein OS=Gallus gallus GN=CISH PE=2 SV=1	9031.ENSGALP00000003536	Cytokine-inducible SH2-containing protein (CIS)(CIS-1)(Suppressor of cytokine signaling)(SOC [...] 	_	KOG4566	_	PF00017.21|SH2|SH2 domain|ENSGALT00000003543|m.7196:93-174;PF07525.13|SOCS_box|SOCS box|ENSGALT00000003543|m.7196:221-254
ENSGALG00000002277	8.307915988	17.41759061	-1.06707911	4.29E-39	1.03E-37	down	yes	7.581095197	8.457586848	8.885065919	17.09850854	16.62192283	18.53234046	9	2716647	2771699	+	KLHL24	protein_coding	GO:0016567|protein ubiquitination; GO:0045109|intermediate filament organization; GO:0051865|protein autoubiquitination; GO:2000312|regulation of kainate selective glutamate receptor activity	GO:0005737|cytoplasm; GO:0005912|adherens junction; GO:0030057|desmosome; GO:0030424|axon; GO:0031463|Cul3-RING ubiquitin ligase complex; GO:0043204|perikaryon	--	ko:K10461|KLHL24_35	--	4088	KFV80884.1	"KFV80884.1 Kelch-like 24, partial [Struthio camelus australis]"	sp|Q6TFL4|KLH24_HUMAN	sp|Q6TFL4|KLH24_HUMAN Kelch-like protein 24 OS=Homo sapiens GN=KLHL24 PE=1 SV=1	_	_	_	_	_	PF07707.12|BACK|BTB And C-terminal Kelch|ENSGALT00000003570|m.8329:168-270;PF00651.28|BTB|BTB/POZ domain|ENSGALT00000003570|m.8329:56-162;PF01344.22|Kelch_1|Kelch motif|ENSGALT00000003570|m.8329:314-349
ENSGALG00000002286	41.82549844	12.511064	1.740370461	9.36E-59	4.44E-57	up	yes	40.05405159	41.66003205	43.76241167	14.90030486	10.6937657	11.93912142	18	4707277	4709117	+	H3F3B	protein_coding	GO:0001649|osteoblast differentiation; GO:0006334|nucleosome assembly; GO:0006336|DNA replication-independent nucleosome assembly; GO:0006997|nucleus organization; GO:0007286|spermatid development; GO:0007338|single fertilization; GO:0007566|embryo implantation; GO:0008283|cell population proliferation; GO:0008584|male gonad development; GO:0030307|positive regulation of cell growth; GO:0031508|pericentric heterochromatin assembly; GO:0031509|telomeric heterochromatin assembly; GO:0035264|multicellular organism growth; GO:0042692|muscle cell differentiation; GO:0048477|oogenesis; GO:0090230|regulation of centromere complex assembly; GO:1902340|negative regulation of chromosome condensation	"GO:0000784|nuclear chromosome, telomeric region; GO:0000786|nucleosome; GO:0000788|nuclear nucleosome; GO:0001740|Barr body; GO:0005634|nucleus; GO:0032991|protein-containing complex; GO:0070062|extracellular exosome"	GO:0000979|RNA polymerase II core promoter sequence-specific DNA binding; GO:0000980|RNA polymerase II distal enhancer sequence-specific DNA binding; GO:0031492|nucleosomal DNA binding; GO:0042393|histone binding; GO:0046982|protein heterodimerization activity	ko:K11253|H3	ko05034|Alcoholism; ko05202|Transcriptional misregulation in cancer; ko05322|Systemic lupus erythematosus	1565	XP_007451114.1	XP_007451114.1 PREDICTED: histone H3.3-like [Lipotes vexillifer]	sp|Q5E9F8|H33_BOVIN	sp|Q5E9F8|H33_BOVIN Histone H3.3 OS=Bos taurus GN=H3F3A PE=1 SV=3	_	_	_	_	_	PF00125.21|Histone|Core histone H2A/H2B/H3/H4|ENSGALT00000088027|m.12710:1-132
ENSGALG00000002318	1.124116999	0.466492397	1.25104438	2.00E-07	6.90E-07	up	yes	0.939992548	1.265113003	1.167245446	0.431072712	0.493987272	0.474417208	Z	73044444	73078736	-	LVRN	protein_coding	GO:0006508|proteolysis; GO:0007165|signal transduction; GO:0007267|cell-cell signaling; GO:0008217|regulation of blood pressure; GO:0043171|peptide catabolic process	GO:0005737|cytoplasm; GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0008270|zinc ion binding; GO:0042277|peptide binding; GO:0070006|metalloaminopeptidase activity	ko:K13724|AQPEP	--	4092	XP_429201.4	XP_429201.4 aminopeptidase Q [Gallus gallus]	sp|Q6Q4G3|AMPQ_HUMAN	sp|Q6Q4G3|AMPQ_HUMAN Aminopeptidase Q OS=Homo sapiens GN=LVRN PE=1 SV=4	9031.ENSGALP00000003642	similar to laeverin	COG0308	KOG1046	_	PF01433.17|Peptidase_M1|Peptidase family M1|ENSGALT00000003649|m.11948:70-472;PF11838.5|ERAP1_C|ERAP1-like C-terminal domain|ENSGALT00000003649|m.11948:612-918
ENSGALG00000002350	1.639785948	3.988407485	-1.277146654	4.61E-24	5.45E-23	down	yes	1.351053567	1.737987659	1.830316618	3.928631674	3.890739431	4.145851349	14	15304269	15344033	-	ENSGALG00000002350	protein_coding	GO:0003341|cilium movement; GO:0036159|inner dynein arm assembly	GO:0005737|cytoplasm; GO:0005874|microtubule; GO:0036156|inner dynein arm	"GO:0005524|ATP binding; GO:0008569|ATP-dependent microtubule motor activity, minus-end-directed; GO:0045503|dynein light chain binding; GO:0045505|dynein intermediate chain binding; GO:0051959|dynein light intermediate chain binding"	ko:K10408|DNAH	ko05016|Huntington's disease	6513	XP_004945524.1	"XP_004945524.1 dynein heavy chain 3, axonemal isoform X1 [Gallus gallus]"	sp|Q8BW94|DYH3_MOUSE	"sp|Q8BW94|DYH3_MOUSE Dynein heavy chain 3, axonemal OS=Mus musculus GN=Dnah3 PE=1 SV=2"	9031.ENSGALP00000003700	"dynein, axonemal, heavy chain 3"	COG5245	KOG3595	_	"PF08393.10|DHC_N2|Dynein heavy chain, N-terminal region 2|ENSGALT00000003708|m.10141:808-1211;PF12774.4|AAA_6|Hydrolytic ATP binding site of dynein motor region D1|ENSGALT00000003708|m.10141:1338-1565;PF07728.11|AAA_5|AAA domain (dynein-related subfamily)|ENSGALT00000003708|m.10141:1654-1795"
ENSGALG00000002370	0.397396668	2.092095566	-2.367322174	1.19E-10	5.61E-10	down	yes	0.578648911	0.224611351	0.388929741	2.304611361	2.046219793	1.925455544	6	4939678	4992201	-	SH2D4B	protein_coding	--	--	--	--	--	1548	XP_001232928.2	XP_001232928.2 SH2 domain-containing protein 4B isoform X1 [Gallus gallus]	sp|Q5SQS7|SH24B_HUMAN	sp|Q5SQS7|SH24B_HUMAN SH2 domain-containing protein 4B OS=Homo sapiens GN=SH2D4B PE=2 SV=1	9031.ENSGALP00000003727	SH2 domain containing 4B	_	_	NOG81798	PF00017.21|SH2|SH2 domain|ENSGALT00000003735|m.4332:270-345
ENSGALG00000002375	9.311062763	33.37607277	-1.840680036	1.23E-154	5.12E-152	down	yes	9.775364236	8.504489419	9.653334634	31.71498035	34.04082293	34.37241504	17	8107664	8143170	+	NOTCH1	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0001701|in utero embryonic development; GO:0001708|cell fate specification; GO:0001837|epithelial to mesenchymal transition; GO:0001889|liver development; GO:0001947|heart looping; GO:0002040|sprouting angiogenesis; GO:0002052|positive regulation of neuroblast proliferation; GO:0002437|inflammatory response to antigenic stimulus; GO:0003157|endocardium development; GO:0003160|endocardium morphogenesis; GO:0003162|atrioventricular node development; GO:0003169|coronary vein morphogenesis; GO:0003180|aortic valve morphogenesis; GO:0003181|atrioventricular valve morphogenesis; GO:0003184|pulmonary valve morphogenesis; GO:0003192|mitral valve formation; GO:0003198|epithelial to mesenchymal transition involved in endocardial cushion formation; GO:0003203|endocardial cushion morphogenesis; GO:0003207|cardiac chamber formation; GO:0003208|cardiac ventricle morphogenesis; GO:0003209|cardiac atrium morphogenesis; GO:0003213|cardiac right atrium morphogenesis; GO:0003214|cardiac left ventricle morphogenesis; GO:0003219|cardiac right ventricle formation; GO:0003222|ventricular trabecula myocardium morphogenesis; GO:0003241|growth involved in heart morphogenesis; GO:0003256|regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation; GO:0003270|Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation; GO:0003273|cell migration involved in endocardial cushion formation; GO:0003344|pericardium morphogenesis; GO:0006355|regulation of transcription, DNA-templated; GO:0006367|transcription initiation from RNA polymerase II promoter; GO:0006955|immune response; GO:0006959|humoral immune response; GO:0007219|Notch signaling pathway; GO:0007221|positive regulation of transcription of Notch receptor target; GO:0007283|spermatogenesis; GO:0007368|determination of left/right symmetry; GO:0007386|compartment pattern specification; GO:0007409|axonogenesis; GO:0007440|foregut morphogenesis; GO:0007492|endoderm development; GO:0007507|heart development; GO:0008284|positive regulation of cell population proliferation; GO:0008285|negative regulation of cell population proliferation; GO:0009912|auditory receptor cell fate commitment; GO:0010718|positive regulation of epithelial to mesenchymal transition; GO:0010812|negative regulation of cell-substrate adhesion; GO:0010832|negative regulation of myotube differentiation; GO:0014031|mesenchymal cell development; GO:0014807|regulation of somitogenesis; GO:0021515|cell differentiation in spinal cord; GO:0021915|neural tube development; GO:0030216|keratinocyte differentiation; GO:0030279|negative regulation of ossification; GO:0030324|lung development; GO:0030335|positive regulation of cell migration; GO:0030513|positive regulation of BMP signaling pathway; GO:0030514|negative regulation of BMP signaling pathway; GO:0030900|forebrain development; GO:0031069|hair follicle morphogenesis; GO:0031100|animal organ regeneration; GO:0031960|response to corticosteroid; GO:0032495|response to muramyl dipeptide; GO:0032496|response to lipopolysaccharide; GO:0035116|embryonic hindlimb morphogenesis; GO:0035148|tube formation; GO:0035914|skeletal muscle cell differentiation; GO:0035924|cellular response to vascular endothelial growth factor stimulus; GO:0042246|tissue regeneration; GO:0043065|positive regulation of apoptotic process; GO:0043086|negative regulation of catalytic activity; GO:0045070|positive regulation of viral genome replication; GO:0045603|positive regulation of endothelial cell differentiation; GO:0045608|negative regulation of inner ear auditory receptor cell differentiation; GO:0045618|positive regulation of keratinocyte differentiation; GO:0045662|negative regulation of myoblast differentiation; GO:0045668|negative regulation of osteoblast differentiation; GO:0045747|positive regulation of Notch signaling pathway; GO:0045892|negative regulation of transcription, DNA-templated; GO:0045893|positive regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0045955|negative regulation of calcium ion-dependent exocytosis; GO:0046427|positive regulation of receptor signaling pathway via JAK-STAT; GO:0046533|negative regulation of photoreceptor cell differentiation; GO:0048103|somatic stem cell division; GO:0048708|astrocyte differentiation; GO:0048709|oligodendrocyte differentiation; GO:0048711|positive regulation of astrocyte differentiation; GO:0048715|negative regulation of oligodendrocyte differentiation; GO:0048754|branching morphogenesis of an epithelial tube; GO:0050679|positive regulation of epithelial cell proliferation; GO:0050768|negative regulation of neurogenesis; GO:0055008|cardiac muscle tissue morphogenesis; GO:0060038|cardiac muscle cell proliferation; GO:0060045|positive regulation of cardiac muscle cell proliferation; GO:0060253|negative regulation of glial cell proliferation; GO:0060271|cilium assembly; GO:0060317|cardiac epithelial to mesenchymal transition; GO:0060411|cardiac septum morphogenesis; GO:0060412|ventricular septum morphogenesis; GO:0060528|secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development; GO:0060740|prostate gland epithelium morphogenesis; GO:0060768|regulation of epithelial cell proliferation involved in prostate gland development; GO:0060842|arterial endothelial cell differentiation; GO:0060843|venous endothelial cell differentiation; GO:0060948|cardiac vascular smooth muscle cell development; GO:0060956|endocardial cell differentiation; GO:0060979|vasculogenesis involved in coronary vascular morphogenesis; GO:0060982|coronary artery morphogenesis; GO:0061314|Notch signaling involved in heart development; GO:0061384|heart trabecula morphogenesis; GO:0061419|positive regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:0070986|left/right axis specification; GO:0071372|cellular response to follicle-stimulating hormone stimulus; GO:0072017|distal tubule development; GO:0072044|collecting duct development; GO:0072144|glomerular mesangial cell development; GO:0072602|interleukin-4 secretion; GO:0090051|negative regulation of cell migration involved in sprouting angiogenesis; GO:0090090|negative regulation of canonical Wnt signaling pathway; GO:0097150|neuronal stem cell population maintenance; GO:1901201|regulation of extracellular matrix assembly; GO:1902263|apoptotic process involved in embryonic digit morphogenesis; GO:1903849|positive regulation of aorta morphogenesis; GO:2000737|negative regulation of stem cell differentiation; GO:2000811|negative regulation of anoikis; GO:2000974|negative regulation of pro-B cell differentiation; GO:2001027|negative regulation of endothelial cell chemotaxis"	GO:0000139|Golgi membrane; GO:0001669|acrosomal vesicle; GO:0002193|MAML1-RBP-Jkappa- ICN1 complex; GO:0005576|extracellular region; GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005789|endoplasmic reticulum membrane; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0005912|adherens junction; GO:0009986|cell surface; GO:0016021|integral component of membrane; GO:0016324|apical plasma membrane; GO:0043235|receptor complex	GO:0001047|core promoter binding; GO:0003700|DNA-binding transcription factor activity; GO:0004857|enzyme inhibitor activity; GO:0004888|transmembrane signaling receptor activity; GO:0005112|Notch binding; GO:0005509|calcium ion binding; GO:0019899|enzyme binding; GO:0031490|chromatin DNA binding; GO:0043565|sequence-specific DNA binding; GO:0046982|protein heterodimerization activity	ko:K02599|NOTCH1	ko01522|Endocrine resistance; ko04320|Dorso-ventral axis formation; ko04330|Notch signaling pathway; ko04658|Th1 and Th2 cell differentiation; ko04919|Thyroid hormone signaling pathway; ko05020|Prion diseases; ko05206|MicroRNAs in cancer; ko05224|Breast cancer	9865	NP_001025466.1	NP_001025466.1 neurogenic locus notch homolog protein 1 [Gallus gallus]	sp|P46531|NOTC1_HUMAN	sp|P46531|NOTC1_HUMAN Neurogenic locus notch homolog protein 1 OS=Homo sapiens GN=NOTCH1 PE=1 SV=4	9031.ENSGALP00000003746	NOTCH-1 Fragment 	COG0666	KOG1217	_	PF00008.24|EGF|EGF-like domain|ENSGALT00000003754|m.12253:73-106;PF00008.24|EGF|EGF-like domain|ENSGALT00000003754|m.12253:116-147;PF00008.24|EGF|EGF-like domain|ENSGALT00000003754|m.12253:154-184;PF00008.24|EGF|EGF-like domain|ENSGALT00000003754|m.12253:232-262;PF00008.24|EGF|EGF-like domain|ENSGALT00000003754|m.12253:271-300;PF00008.24|EGF|EGF-like domain|ENSGALT00000003754|m.12253:309-340;PF00008.24|EGF|EGF-like domain|ENSGALT00000003754|m.12253:426-458;PF00008.24|EGF|EGF-like domain|ENSGALT00000003754|m.12253:466-494;PF00008.24|EGF|EGF-like domain|ENSGALT00000003754|m.12253:504-532;PF00008.24|EGF|EGF-like domain|ENSGALT00000003754|m.12253:542-571;PF00008.24|EGF|EGF-like domain|ENSGALT00000003754|m.12253:580-609;PF00008.24|EGF|EGF-like domain|ENSGALT00000003754|m.12253:655-683;PF00008.24|EGF|EGF-like domain|ENSGALT00000003754|m.12253:692-720;PF00008.24|EGF|EGF-like domain|ENSGALT00000003754|m.12253:730-758;PF00008.24|EGF|EGF-like domain|ENSGALT00000003754|m.12253:767-797;PF00008.24|EGF|EGF-like domain|ENSGALT00000003754|m.12253:805-834;PF00008.24|EGF|EGF-like domain|ENSGALT00000003754|m.12253:883-913;PF00008.24|EGF|EGF-like domain|ENSGALT00000003754|m.12253:921-949;PF00008.24|EGF|EGF-like domain|ENSGALT00000003754|m.12253:959-989;PF00008.24|EGF|EGF-like domain|ENSGALT00000003754|m.12253:997-1027;PF00008.24|EGF|EGF-like domain|ENSGALT00000003754|m.12253:1035-1064;PF00008.24|EGF|EGF-like domain|ENSGALT00000003754|m.12253:1073-1102;PF00008.24|EGF|EGF-like domain|ENSGALT00000003754|m.12253:1126-1151;PF00008.24|EGF|EGF-like domain|ENSGALT00000003754|m.12253:1159-1188;PF00008.24|EGF|EGF-like domain|ENSGALT00000003754|m.12253:1197-1225;PF00008.24|EGF|EGF-like domain|ENSGALT00000003754|m.12253:1245-1273;PF00008.24|EGF|EGF-like domain|ENSGALT00000003754|m.12253:1281-1313;PF00008.24|EGF|EGF-like domain|ENSGALT00000003754|m.12253:1321-1353;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000003754|m.12253:188-224;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000003754|m.12253:305-339;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000003754|m.12253:422-455;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000003754|m.12253:462-493;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000003754|m.12253:538-569;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000003754|m.12253:689-721;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000003754|m.12253:879-910;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000003754|m.12253:917-948;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000003754|m.12253:1032-1064;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000003754|m.12253:1156-1190;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000003754|m.12253:1247-1270;PF12661.4|hEGF|Human growth factor-like EGF|ENSGALT00000003754|m.12253:136-148;PF12661.4|hEGF|Human growth factor-like EGF|ENSGALT00000003754|m.12253:253-264;PF12661.4|hEGF|Human growth factor-like EGF|ENSGALT00000003754|m.12253:330-342;PF12661.4|hEGF|Human growth factor-like EGF|ENSGALT00000003754|m.12253:447-459;PF12661.4|hEGF|Human growth factor-like EGF|ENSGALT00000003754|m.12253:749-760;PF12661.4|hEGF|Human growth factor-like EGF|ENSGALT00000003754|m.12253:978-990;PF12661.4|hEGF|Human growth factor-like EGF|ENSGALT00000003754|m.12253:1016-1028;PF12661.4|hEGF|Human growth factor-like EGF|ENSGALT00000003754|m.12253:1054-1066;PF12661.4|hEGF|Human growth factor-like EGF|ENSGALT00000003754|m.12253:1263-1274;PF00066.14|Notch|LNR domain|ENSGALT00000003754|m.12253:1457-1490;PF00066.14|Notch|LNR domain|ENSGALT00000003754|m.12253:1497-1532;PF00066.14|Notch|LNR domain|ENSGALT00000003754|m.12253:1537-1571;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000003754|m.12253:1923-1999;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000003754|m.12253:2009-2099;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000003754|m.12253:1890-1935;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000003754|m.12253:1938-1969;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000003754|m.12253:2004-2036;PF11936.5|DUF3454|Domain of unknown function (DUF3454)|ENSGALT00000003754|m.12253:2486-2545;PF06816.10|NOD|NOTCH protein|ENSGALT00000003754|m.12253:1576-1631;PF07684.9|NODP|NOTCH protein|ENSGALT00000003754|m.12253:1681-1737;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000003754|m.12253:1930-1975;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000003754|m.12253:1938-1966;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000003754|m.12253:1940-1980;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000003754|m.12253:2040-2091
ENSGALG00000002386	0.160199319	0.564499096	-1.755079356	0.000290628	0.000664961	down	yes	0.104753656	0.184333132	0.191511169	0.457073617	0.604873447	0.631550224	Z	9080563	9084664	-	TMEM8B	protein_coding	GO:0007160|cell-matrix adhesion; GO:0040008|regulation of growth	GO:0005634|nucleus; GO:0005739|mitochondrion; GO:0005783|endoplasmic reticulum; GO:0005886|plasma membrane; GO:0009986|cell surface; GO:0016021|integral component of membrane	--	--	--	2515	XP_001233115.3	XP_001233115.3 transmembrane protein 8B isoform X1 [Gallus gallus]	sp|B1AWJ5|TMM8B_MOUSE	sp|B1AWJ5|TMM8B_MOUSE Transmembrane protein 8B OS=Mus musculus GN=Tmem8b PE=2 SV=1	8364.ENSXETP00000021711	transmembrane protein 8B	_	_	NOG77604	PF12036.5|DUF3522|Protein of unknown function (DUF3522)|ENSGALT00000003755|m.10524:344-526
ENSGALG00000002466	0.812515433	3.792064297	-2.208668276	5.27E-19	4.68E-18	down	yes	0.536686248	1.054014704	0.846845347	3.266025806	4.950146944	3.16002014	21	3244323	3253164	-	SLC2A5	protein_coding	GO:0003044|regulation of systemic arterial blood pressure mediated by a chemical signal; GO:0005975|carbohydrate metabolic process; GO:0009750|response to fructose; GO:0015755|fructose transmembrane transport; GO:0043312|neutrophil degranulation; GO:0071332|cellular response to fructose stimulus; GO:0106001|intestinal hexose absorption; GO:1904659|glucose transmembrane transport; GO:1990539|fructose import across plasma membrane	GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0016324|apical plasma membrane; GO:0035579|specific granule membrane; GO:0042383|sarcolemma; GO:0070062|extracellular exosome	GO:0005353|fructose transmembrane transporter activity; GO:0005355|glucose transmembrane transporter activity; GO:0070061|fructose binding	"ko:K08143|SLC2A5,GLUT5"	ko04973|Carbohydrate digestion and absorption	2749	XP_417596.4	"XP_417596.4 solute carrier family 2, facilitated glucose transporter member 5 isoform X2 [Gallus gallus]"	sp|P22732|GTR5_HUMAN	"sp|P22732|GTR5_HUMAN Solute carrier family 2, facilitated glucose transporter member 5 OS=Homo sapiens GN=SLC2A5 PE=1 SV=1"	9031.ENSGALP00000003884	"solute carrier family 2 (facilitated glucose/fructose transporter), member 5"	COG0477	KOG0569	_	PF00083.21|Sugar_tr|Sugar (and other) transporter|ENSGALT00000003893|m.3996:28-482;PF07690.13|MFS_1|Major Facilitator Superfamily|ENSGALT00000003893|m.3996:35-411
ENSGALG00000002501	45.0678469	17.10032265	1.397551643	2.24E-91	2.33E-89	up	yes	43.75280314	46.0156818	45.43505577	17.66116057	16.45194723	17.18786016	19	5055814	5067156	+	VKORC1L1	protein_coding	GO:0017187|peptidyl-glutamic acid carboxylation; GO:0034599|cellular response to oxidative stress; GO:0042373|vitamin K metabolic process	GO:0005783|endoplasmic reticulum; GO:0005789|endoplasmic reticulum membrane; GO:0016021|integral component of membrane	GO:0047057|vitamin-K-epoxide reductase (warfarin-sensitive) activity; GO:0048038|quinone binding	ko:K05357|VKORC1	ko00130|Ubiquinone and other terpenoid-quinone biosynthesis; ko01110|Biosynthesis of secondary metabolites	2470	NP_001001328.1	NP_001001328.1 vitamin K epoxide reductase complex subunit 1-like protein 1 [Gallus gallus]	sp|Q8N0U8|VKORL_HUMAN	sp|Q8N0U8|VKORL_HUMAN Vitamin K epoxide reductase complex subunit 1-like protein 1 OS=Homo sapiens GN=VKORC1L1 PE=1 SV=2	59729.ENSTGUP00000005416	Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1-like protein 1) [Taenio [...] 	_	KOG0359	NOG46570	PF07884.11|VKOR|Vitamin K epoxide reductase family|ENSGALT00000003944|m.13769:22-158
ENSGALG00000002515	2.950781362	13.63866023	-2.204709477	3.13E-102	4.03E-100	down	yes	3.073646864	2.829195496	2.949501727	14.61449507	12.70871378	13.59277184	17	7899618	7927026	+	OLFM1	protein_coding	GO:0003190|atrioventricular valve formation; GO:0010628|positive regulation of gene expression; GO:0010629|negative regulation of gene expression; GO:0010718|positive regulation of epithelial to mesenchymal transition; GO:0022900|electron transport chain; GO:0023041|neuronal signal transduction; GO:0030516|regulation of axon extension; GO:0060317|cardiac epithelial to mesenchymal transition	GO:0005615|extracellular space; GO:0005623|cell; GO:0005783|endoplasmic reticulum; GO:0030054|cell junction; GO:0030424|axon; GO:0043025|neuronal cell body; GO:0043204|perikaryon; GO:0044295|axonal growth cone; GO:0045202|synapse	GO:0005506|iron ion binding; GO:0009055|electron transfer activity; GO:0020037|heme binding	--	--	2913	XP_006028687.1	XP_006028687.1 noelin isoform X2 [Alligator sinensis]	sp|Q9IAK4|NOE1_CHICK	sp|Q9IAK4|NOE1_CHICK Noelin OS=Gallus gallus GN=OLFM1 PE=1 SV=1	_	_	_	_	_	PF02191.13|OLF|Olfactomedin-like domain|ENSGALT00000089302|m.12231:202-447;PF12308.5|Noelin-1|Neurogenesis glycoprotein|ENSGALT00000089302|m.12231:27-124
ENSGALG00000002519	13.98765939	38.59295719	-1.463525762	2.20E-50	8.02E-49	down	yes	13.56781922	14.2826804	14.11247854	43.43108032	33.92016089	38.42763035	21	3403876	3423372	+	SLC25A33	protein_coding	GO:0000002|mitochondrial genome maintenance; GO:0002082|regulation of oxidative phosphorylation; GO:0006390|mitochondrial transcription; GO:0006839|mitochondrial transport; GO:0006864|pyrimidine nucleotide transport; GO:0007005|mitochondrion organization; GO:0008284|positive regulation of cell population proliferation; GO:0030307|positive regulation of cell growth; GO:0031930|mitochondria-nucleus signaling pathway; GO:0032869|cellular response to insulin stimulus; GO:0034551|mitochondrial respiratory chain complex III assembly; GO:0051881|regulation of mitochondrial membrane potential; GO:0071156|regulation of cell cycle arrest; GO:1903426|regulation of reactive oxygen species biosynthetic process; GO:1990314|cellular response to insulin-like growth factor stimulus; GO:1990519|pyrimidine nucleotide import into mitochondrion	GO:0005743|mitochondrial inner membrane; GO:0016021|integral component of membrane; GO:0031966|mitochondrial membrane	GO:0015218|pyrimidine nucleotide transmembrane transporter activity	"ko:K15116|SLC25A33_36,RIM2"	--	1934	XP_417600.1	XP_417600.1 solute carrier family 25 member 33 isoform X1 [Gallus gallus]	sp|Q9BSK2|S2533_HUMAN	sp|Q9BSK2|S2533_HUMAN Solute carrier family 25 member 33 OS=Homo sapiens GN=SLC25A33 PE=1 SV=1	9031.ENSGALP00000003960	"solute carrier family 25, member 33"	_	KOG0757	_	PF00153.24|Mito_carr|Mitochondrial carrier protein|ENSGALT00000003969|m.4006:8-118;PF00153.24|Mito_carr|Mitochondrial carrier protein|ENSGALT00000003969|m.4006:126-213;PF00153.24|Mito_carr|Mitochondrial carrier protein|ENSGALT00000003969|m.4006:230-315
ENSGALG00000002525	4.290013848	13.19516075	-1.618688653	1.45E-52	5.73E-51	down	yes	3.676672361	4.888736346	4.304632836	12.74025562	14.2886226	12.55660402	6	5430790	5475162	+	RASGEF1A	protein_coding	GO:0007264|small GTPase mediated signal transduction; GO:0016477|cell migration	GO:0005622|intracellular	GO:0005088|Ras guanyl-nucleotide exchange factor activity	--	--	3358	CAG31417.1	CAG31417.1 hypothetical protein RCJMB04_6c20 [Gallus gallus]	sp|A0JM95|RGF1A_XENTR	sp|A0JM95|RGF1A_XENTR Ras-GEF domain-containing family member 1A OS=Xenopus tropicalis GN=rasgef1a PE=2 SV=1	9031.ENSGALP00000033589	"RasGEF domain family, member 1A "	_	KOG3541	_	PF00618.17|RasGEF_N|RasGEF N-terminal motif|ENSGALT00000088743|m.4350:53-152;PF00617.16|RasGEF|RasGEF domain|ENSGALT00000088743|m.4350:228-293;PF00617.16|RasGEF|RasGEF domain|ENSGALT00000088743|m.4351:4-128
ENSGALG00000002546	0.099758994	0.274875979	-1.37599482	0.000806005	0.001721881	down	yes	0.031933993	0.131118577	0.13622441	0.33152882	0.219758131	0.273340986	17	7734269	7862385	+	COL5A1	protein_coding	"GO:0001568|blood vessel development; GO:0003007|heart morphogenesis; GO:0007155|cell adhesion; GO:0016477|cell migration; GO:0030199|collagen fibril organization; GO:0032964|collagen biosynthetic process; GO:0035313|wound healing, spreading of epidermal cells; GO:0035989|tendon development; GO:0043588|skin development; GO:0045112|integrin biosynthetic process; GO:0048592|eye morphogenesis; GO:0051128|regulation of cellular component organization; GO:0097435|supramolecular fiber organization; GO:1903225|negative regulation of endodermal cell differentiation"	GO:0005581|collagen trimer; GO:0005588|collagen type V trimer; GO:0005604|basement membrane; GO:0005615|extracellular space; GO:0031012|extracellular matrix; GO:0070062|extracellular exosome	GO:0005201|extracellular matrix structural constituent; GO:0008201|heparin binding; GO:0043394|proteoglycan binding; GO:0048407|platelet-derived growth factor binding	ko:K19721|COL5AS	ko04974|Protein digestion and absorption	8250	NP_990121.2	NP_990121.2 collagen alpha-1(V) chain precursor [Gallus gallus]	sp|O88207|CO5A1_MOUSE	sp|O88207|CO5A1_MOUSE Collagen alpha-1(V) chain OS=Mus musculus GN=Col5a1 PE=1 SV=2	9031.ENSGALP00000038245	alpha 1 (V) collagen 	_	KOG3544	_	PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000059123|m.12224:465-513;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000059123|m.12224:558-615;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000059123|m.12224:765-823;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000059123|m.12224:1041-1098;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000059123|m.12224:1509-1567;PF01410.15|COLFI|Fibrillar collagen C-terminal domain|ENSGALT00000059123|m.12224:1605-1833
ENSGALG00000002549	0.335211363	35.549462	-6.686609735	5.81E-180	3.35E-177	down	yes	0.361278565	0.305642028	0.338713496	37.97722386	34.4790932	34.19206894	8	3999641	4003821	-	RGS1	protein_coding	GO:0007165|signal transduction; GO:0007186|G protein-coupled receptor signaling pathway; GO:0008277|regulation of G protein-coupled receptor signaling pathway; GO:0009968|negative regulation of signal transduction; GO:0043547|positive regulation of GTPase activity; GO:0061737|leukotriene signaling pathway	GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0031234|extrinsic component of cytoplasmic side of plasma membrane	GO:0001965|G-protein alpha-subunit binding; GO:0005096|GTPase activator activity	ko:K16449|RGS	--	1896	XP_422203.4	XP_422203.4 regulator of G-protein signaling 1 [Gallus gallus]	sp|Q9JL25|RGS1_MOUSE	sp|Q9JL25|RGS1_MOUSE Regulator of G-protein signaling 1 OS=Mus musculus GN=Rgs1 PE=2 SV=2	9031.ENSGALP00000033391	regulator of G-protein signalling 1	_	KOG3589	_	PF00615.16|RGS|Regulator of G protein signaling domain|ENSGALT00000034033|m.6978:85-199
ENSGALG00000002553	28.12788949	6.899616294	2.02583662	3.99E-181	2.41E-178	up	yes	27.84603633	28.83085162	27.70678053	7.121705408	6.86657333	6.710570145	13	2788001	2834253	+	PCDH1	protein_coding	GO:0007156|homophilic cell adhesion via plasma membrane adhesion molecules; GO:0007267|cell-cell signaling; GO:0007399|nervous system development	GO:0005634|nucleus; GO:0005730|nucleolus; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0005911|cell-cell junction; GO:0030054|cell junction; GO:0043231|intracellular membrane-bounded organelle	GO:0005509|calcium ion binding	ko:K16498|PCDHD1	--	4001	XP_015149085.1	XP_015149085.1 protocadherin-1 isoform X1 [Gallus gallus]	sp|Q08174|PCDH1_HUMAN	sp|Q08174|PCDH1_HUMAN Protocadherin-1 OS=Homo sapiens GN=PCDH1 PE=1 SV=2	_	_	_	_	_	PF00028.14|Cadherin|Cadherin domain|ENSGALT00000104852|m.8390:167-262;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000104852|m.8390:277-369;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000104852|m.8390:394-488;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000104852|m.8390:505-594;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000104852|m.8390:609-698;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000104852|m.8390:722-804;PF08374.8|Protocadherin|Protocadherin|ENSGALT00000104852|m.8390:807-1020;PF08266.9|Cadherin_2|Cadherin-like|ENSGALT00000104852|m.8390:52-132
ENSGALG00000002555	1.656749789	4.368641615	-1.393445828	1.63E-15	1.13E-14	down	yes	1.275813295	2.182663971	1.511772101	4.622987148	4.019816646	4.463121051	6	5520195	5598425	-	RET	protein_coding	"GO:0000165|MAPK cascade; GO:0001657|ureteric bud development; GO:0001755|neural crest cell migration; GO:0001838|embryonic epithelial tube formation; GO:0006468|protein phosphorylation; GO:0006919|activation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0007156|homophilic cell adhesion via plasma membrane adhesion molecules; GO:0007158|neuron cell-cell adhesion; GO:0007165|signal transduction; GO:0007169|transmembrane receptor protein tyrosine kinase signaling pathway; GO:0007411|axon guidance; GO:0007497|posterior midgut development; GO:0010976|positive regulation of neuron projection development; GO:0014042|positive regulation of neuron maturation; GO:0030155|regulation of cell adhesion; GO:0030335|positive regulation of cell migration; GO:0033141|positive regulation of peptidyl-serine phosphorylation of STAT protein; GO:0033619|membrane protein proteolysis; GO:0033630|positive regulation of cell adhesion mediated by integrin; GO:0035799|ureter maturation; GO:0042493|response to drug; GO:0042551|neuron maturation; GO:0045793|positive regulation of cell size; GO:0045893|positive regulation of transcription, DNA-templated; GO:0048265|response to pain; GO:0048484|enteric nervous system development; GO:0050770|regulation of axonogenesis; GO:0060041|retina development in camera-type eye; GO:0060384|innervation; GO:0061146|Peyer's patch morphogenesis; GO:0071300|cellular response to retinoic acid; GO:0072300|positive regulation of metanephric glomerulus development; GO:0097021|lymphocyte migration into lymphoid organs; GO:2001241|positive regulation of extrinsic apoptotic signaling pathway in absence of ligand"	GO:0005769|early endosome; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0010008|endosome membrane; GO:0030424|axon; GO:0030425|dendrite; GO:0043025|neuronal cell body; GO:0043231|intracellular membrane-bounded organelle; GO:0043235|receptor complex; GO:0045121|membrane raft; GO:0098797|plasma membrane protein complex	GO:0004713|protein tyrosine kinase activity; GO:0004714|transmembrane receptor protein tyrosine kinase activity; GO:0005088|Ras guanyl-nucleotide exchange factor activity; GO:0005509|calcium ion binding; GO:0005524|ATP binding; GO:0038023|signaling receptor activity	ko:K05126|RET	ko04144|Endocytosis; ko05200|Pathways in cancer; ko05216|Thyroid cancer; ko05230|Central carbon metabolism in cancer	3620	XP_015143444.1	XP_015143444.1 proto-oncogene tyrosine-protein kinase receptor Ret isoform X1 [Gallus gallus]	sp|P07949|RET_HUMAN	sp|P07949|RET_HUMAN Proto-oncogene tyrosine-protein kinase receptor Ret OS=Homo sapiens GN=RET PE=1 SV=3	9031.ENSGALP00000004029	ret proto-oncogene 	COG0515	KOG0200	_	PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000084496|m.4355:715-996;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000084496|m.4355:718-994;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000084496|m.4355:162-251
ENSGALG00000002564	0.389039477	1.102192713	-1.478803407	2.36E-05	6.32E-05	down	yes	0.514059406	0.40831787	0.244741154	1.055437057	1.270678851	0.980462231	8	4066661	4072187	+	RGS4	protein_coding	GO:0007186|G protein-coupled receptor signaling pathway; GO:0009968|negative regulation of signal transduction	GO:0005737|cytoplasm; GO:0005886|plasma membrane	GO:0005096|GTPase activator activity	ko:K16449|RGS	--	2360	XP_003208663.1	XP_003208663.1 PREDICTED: regulator of G-protein signaling 4 [Meleagris gallopavo]	sp|Q7SZC6|RGS4_CHICK	sp|Q7SZC6|RGS4_CHICK Regulator of G-protein signaling 4 OS=Gallus gallus GN=RGS4 PE=2 SV=1	_	_	_	_	_	PF00615.16|RGS|Regulator of G protein signaling domain|ENSGALT00000004050|m.6981:62-177
ENSGALG00000002594	0.089621314	0.308878801	-1.678481845	0.004417604	0.008362511	down	yes	0.030360754	0.111302657	0.127200531	0.171302141	0.354223237	0.401111025	7	999492	1117976	+	TFPI	protein_coding	"GO:0007596|blood coagulation; GO:0007598|blood coagulation, extrinsic pathway; GO:0032355|response to estradiol; GO:0071222|cellular response to lipopolysaccharide; GO:0071347|cellular response to interleukin-1"	GO:0005576|extracellular region; GO:0005615|extracellular space; GO:0005783|endoplasmic reticulum; GO:0005886|plasma membrane; GO:0009986|cell surface; GO:0031090|organelle membrane; GO:0031225|anchored component of membrane	GO:0004866|endopeptidase inhibitor activity; GO:0004867|serine-type endopeptidase inhibitor activity	ko:K03909|TFPI	ko04610|Complement and coagulation cascades	1962	XP_004942459.1	XP_004942459.1 tissue factor pathway inhibitor isoform X1 [Gallus gallus]	sp|P10646|TFPI1_HUMAN	sp|P10646|TFPI1_HUMAN Tissue factor pathway inhibitor OS=Homo sapiens GN=TFPI PE=1 SV=1	9031.ENSGALP00000033380	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)	_	KOG4295	_	PF00014.20|Kunitz_BPTI|Kunitz/Bovine pancreatic trypsin inhibitor domain|ENSGALT00000092807|m.5603:52-102;PF00014.20|Kunitz_BPTI|Kunitz/Bovine pancreatic trypsin inhibitor domain|ENSGALT00000092807|m.5603:123-175;PF00014.20|Kunitz_BPTI|Kunitz/Bovine pancreatic trypsin inhibitor domain|ENSGALT00000092807|m.5603:218-269
ENSGALG00000002615	1.069934437	3.118818492	-1.534674239	8.36E-13	4.70E-12	down	yes	1.01728265	0.958978958	1.233541703	2.662924853	3.185809166	3.507721456	26	4108401	4119816	-	DEF6	protein_coding	--	GO:0005654|nucleoplasm; GO:0005829|cytosol; GO:0005856|cytoskeleton; GO:0005886|plasma membrane; GO:0016020|membrane; GO:0030175|filopodium; GO:0048471|perinuclear region of cytoplasm	--	--	--	2538	XP_015154492.1	XP_015154492.1 differentially expressed in FDCP 6 homolog isoform X2 [Gallus gallus]	sp|Q9H4E7|DEFI6_HUMAN	sp|Q9H4E7|DEFI6_HUMAN Differentially expressed in FDCP 6 homolog OS=Homo sapiens GN=DEF6 PE=1 SV=1	9031.ENSGALP00000004108	differentially expressed in FDCP 6 homolog (mouse)	_	_	NOG117655	PF00169.26|PH|PH domain|ENSGALT00000004117|m.8184:224-319;PF14593.3|PH_3|PH domain|ENSGALT00000004117|m.8184:222-319
ENSGALG00000002666	18.78742283	9.17235143	1.033599325	6.29E-35	1.25E-33	up	yes	19.25936503	18.30067808	18.80222537	9.142952539	9.401877881	8.972223871	14	13409979	13450780	+	RAB11FIP3	protein_coding	GO:0000910|cytokinesis; GO:0016192|vesicle-mediated transport; GO:0032456|endocytic recycling; GO:0061512|protein localization to cilium; GO:0070164|negative regulation of adiponectin secretion	GO:0005654|nucleoplasm; GO:0005768|endosome; GO:0005813|centrosome; GO:0005815|microtubule organizing center; GO:0005829|cytosol; GO:0030496|midbody; GO:0032154|cleavage furrow; GO:0043231|intracellular membrane-bounded organelle; GO:0045171|intercellular bridge; GO:0055037|recycling endosome; GO:0055038|recycling endosome membrane	GO:0005509|calcium ion binding; GO:0017137|Rab GTPase binding; GO:0030306|ADP-ribosylation factor binding; GO:0042803|protein homodimerization activity; GO:0051959|dynein light intermediate chain binding	ko:K12485|RAB11FIP3_4	ko04144|Endocytosis	2503	XP_004945476.1	XP_004945476.1 rab11 family-interacting protein 3 isoform X1 [Gallus gallus]	sp|O75154|RFIP3_HUMAN	sp|O75154|RFIP3_HUMAN Rab11 family-interacting protein 3 OS=Homo sapiens GN=RAB11FIP3 PE=1 SV=1	59729.ENSTGUP00000003875	Rab11 family-interacting protein 3 (Rab11-FIP3)(EF hands-containing Rab-interacting protein) [...] 	_	KOG0982	_	PF13499.3|EF-hand_7|EF-hand domain pair|ENSGALT00000102820|m.9936:71-127
ENSGALG00000002675	0.243536875	0.759826018	-1.602336841	8.91E-06	2.52E-05	down	yes	0.192654805	0.317823008	0.220132811	0.766939832	0.825437937	0.687100284	26	4137342	4159954	-	SCUBE3	protein_coding	GO:0007165|signal transduction; GO:0022617|extracellular matrix disassembly; GO:0030154|cell differentiation; GO:0045880|positive regulation of smoothened signaling pathway; GO:0051260|protein homooligomerization; GO:0051291|protein heterooligomerization	GO:0005615|extracellular space; GO:0005886|plasma membrane; GO:0009986|cell surface	GO:0005509|calcium ion binding	--	--	2931	XP_418021.3	"XP_418021.3 signal peptide, CUB and EGF-like domain-containing protein 3 isoform X5 [Gallus gallus]"	sp|Q8IX30|SCUB3_HUMAN	"sp|Q8IX30|SCUB3_HUMAN Signal peptide, CUB and EGF-like domain-containing protein 3 OS=Homo sapiens GN=SCUBE3 PE=1 SV=1"	9031.ENSGALP00000004206	"signal peptide, CUB domain, EGF-like 3"	_	KOG1217	_	PF14670.3|FXa_inhibition|Coagulation Factor Xa inhibitory site|ENSGALT00000004215|m.8189:108-143;PF14670.3|FXa_inhibition|Coagulation Factor Xa inhibitory site|ENSGALT00000004215|m.8189:232-267;PF14670.3|FXa_inhibition|Coagulation Factor Xa inhibitory site|ENSGALT00000004215|m.8189:273-308;PF12662.4|cEGF|Complement Clr-like EGF-like|ENSGALT00000004215|m.8189:44-65;PF12662.4|cEGF|Complement Clr-like EGF-like|ENSGALT00000004215|m.8189:85-107;PF12662.4|cEGF|Complement Clr-like EGF-like|ENSGALT00000004215|m.8189:251-272;PF12662.4|cEGF|Complement Clr-like EGF-like|ENSGALT00000004215|m.8189:290-313;PF07699.10|Ephrin_rec_like|Putative ephrin-receptor like|ENSGALT00000004215|m.8189:625-672;PF07699.10|Ephrin_rec_like|Putative ephrin-receptor like|ENSGALT00000004215|m.8189:679-726;PF07699.10|Ephrin_rec_like|Putative ephrin-receptor like|ENSGALT00000004215|m.8189:735-782;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000004215|m.8189:21-60;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000004215|m.8189:62-102;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000004215|m.8189:104-143;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000004215|m.8189:269-307;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000004215|m.8189:310-340;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000004215|m.8189:349-387;PF12947.4|EGF_3|EGF domain|ENSGALT00000004215|m.8189:25-60;PF00431.17|CUB|CUB domain|ENSGALT00000004215|m.8189:787-896;PF00008.24|EGF|EGF-like domain|ENSGALT00000004215|m.8189:25-56
ENSGALG00000002692	0.623744038	1.46244077	-1.216237427	0.00099063	0.002087874	down	yes	0.707512857	0.709867109	0.453852147	1.554757601	1.502184863	1.330379847	26	4178714	4184847	+	ENSGALG00000002692	protein_coding	GO:0007275|multicellular organism development; GO:0007283|spermatogenesis; GO:0010737|protein kinase A signaling; GO:0030154|cell differentiation; GO:0043949|regulation of cAMP-mediated signaling; GO:1902490|regulation of sperm capacitation	GO:0001669|acrosomal vesicle; GO:0016021|integral component of membrane; GO:0036126|sperm flagellum; GO:0097225|sperm midpiece	--	--	--	1415	XP_024999640.1	XP_024999640.1 T-complex protein 11 homolog isoform X2 [Gallus gallus]	sp|Q8WWU5|TCP11_HUMAN	sp|Q8WWU5|TCP11_HUMAN T-complex protein 11 homolog OS=Homo sapiens GN=TCP11 PE=1 SV=1	9031.ENSGALP00000004234	t-complex 11 homolog (mouse)	_	KOG1981	_	PF05794.10|Tcp11|T-complex protein 11|ENSGALT00000004243|m.8195:25-354
ENSGALG00000002705	104.975919	49.57323647	1.082271494	1.64E-83	1.43E-81	up	yes	100.7744184	106.6518779	107.5014608	49.47437875	48.80330601	50.44202465	6	5951613	5961190	+	CISD1	protein_coding	GO:0043457|regulation of cellular respiration	GO:0005739|mitochondrion; GO:0005741|mitochondrial outer membrane; GO:0016021|integral component of membrane; GO:0070062|extracellular exosome	"GO:0005506|iron ion binding; GO:0042802|identical protein binding; GO:0051537|2 iron, 2 sulfur cluster binding"	--	--	2916	NP_001186458.1	NP_001186458.1 CDGSH iron-sulfur domain-containing protein 1 [Gallus gallus]	sp|Q91WS0|CISD1_MOUSE	sp|Q91WS0|CISD1_MOUSE CDGSH iron-sulfur domain-containing protein 1 OS=Mus musculus GN=Cisd1 PE=1 SV=1	_	_	_	_	_	PF09360.7|zf-CDGSH|Iron-binding zinc finger CDGSH type|ENSGALT00000004265|m.4387:75-97;PF10660.6|MitoNEET_N|Iron-containing outer mitochondrial membrane protein N-terminus|ENSGALT00000004265|m.4387:22-50
ENSGALG00000002728	31.99285609	7.10369955	2.169528716	1.76E-129	4.93E-127	up	yes	35.51270235	29.45159873	31.0142672	6.691097116	7.5876795	7.032322034	18	4866126	4876014	-	SLC16A3	protein_coding	--	GO:0005887|integral component of plasma membrane	GO:0015129|lactate transmembrane transporter activity; GO:0015293|symporter activity	ko:K08180|SLC16A3	ko05230|Central carbon metabolism in cancer	3282	AAG25703.1	AAG25703.1 monocarboxylate transporter 4 [Gallus gallus]	sp|P57788|MOT4_CHICK	sp|P57788|MOT4_CHICK Monocarboxylate transporter 4 OS=Gallus gallus GN=SLC16A3 PE=2 SV=1	9031.ENSGALP00000004297	Monocarboxylate transporter 4 (MCT 4)(Solute carrier family 16 member 3); Proton-linked mono [...] 	COG0477	KOG2504	_	PF07690.13|MFS_1|Major Facilitator Superfamily|ENSGALT00000004306|m.12722:54-401
ENSGALG00000002744	0.283633815	1.635826652	-2.486722369	2.55E-40	6.52E-39	down	yes	0.348562883	0.231903034	0.270435527	1.629179262	1.615971002	1.662329692	6	7005075	7303413	+	PCDH15	protein_coding	GO:0001964|startle response; GO:0002009|morphogenesis of an epithelium; GO:0007155|cell adhesion; GO:0007156|homophilic cell adhesion via plasma membrane adhesion molecules; GO:0007267|cell-cell signaling; GO:0007399|nervous system development; GO:0007601|visual perception; GO:0007628|adult walking behavior; GO:0035264|multicellular organism growth; GO:0050910|detection of mechanical stimulus involved in sensory perception of sound; GO:0050973|detection of mechanical stimulus involved in equilibrioception; GO:0051017|actin filament bundle assembly; GO:0060013|righting reflex; GO:0060088|auditory receptor cell stereocilium organization; GO:1905515|non-motile cilium assembly	GO:0001750|photoreceptor outer segment; GO:0005737|cytoplasm; GO:0005887|integral component of plasma membrane; GO:0032420|stereocilium	GO:0005509|calcium ion binding	ko:K16500|PCDH15	--	6679	NP_001038119.1	NP_001038119.1 protocadherin-15 precursor [Gallus gallus]	sp|Q0ZM14|PCD15_CHICK	sp|Q0ZM14|PCD15_CHICK Protocadherin-15 OS=Gallus gallus GN=Pcdh15 PE=1 SV=1	_	_	_	_	_	PF00028.14|Cadherin|Cadherin domain|ENSGALT00000004324|m.4395:153-256;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000004324|m.4395:418-499;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000004324|m.4395:524-606;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000004324|m.4395:621-708;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000004324|m.4395:724-810;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000004324|m.4395:824-916;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000004324|m.4395:938-1027;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000004324|m.4395:1045-1134
ENSGALG00000002766	0.9795015	5.095280296	-2.367216372	5.97E-25	7.41E-24	down	yes	1.093932646	0.779792578	1.064779277	4.617728784	5.816689992	4.851422111	11	1886612	1890948	-	MLKL	protein_coding	GO:0035556|intracellular signal transduction; GO:0070207|protein homotrimerization; GO:0070266|necroptotic process	GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005886|plasma membrane	GO:0005524|ATP binding; GO:0019901|protein kinase binding; GO:0042802|identical protein binding; GO:0044877|protein-containing complex binding	ko:K08849|MLKL	ko04668|TNF signaling pathway	1734	XP_015134716.1	XP_015134716.1 mixed lineage kinase domain-like protein [Gallus gallus]	sp|Q8NB16|MLKL_HUMAN	sp|Q8NB16|MLKL_HUMAN Mixed lineage kinase domain-like protein OS=Homo sapiens GN=MLKL PE=1 SV=1	9031.ENSGALP00000004360	annotation not avaliable	COG0515	KOG4721	_	PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000004369|m.6353:226-475;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000004369|m.6353:234-472
ENSGALG00000002771	12.46611134	4.566383352	1.446888519	1.59E-13	9.46E-13	up	yes	14.43674927	12.10356563	10.85801911	5.613660274	4.481015915	3.604473866	8	4371681	4375045	-	CRIP1	protein_coding	GO:0008630|intrinsic apoptotic signaling pathway in response to DNA damage; GO:0010043|response to zinc ion; GO:0071236|cellular response to antibiotic; GO:0071493|cellular response to UV-B	GO:0005737|cytoplasm	"GO:0003680|AT DNA binding; GO:0008270|zinc ion binding; GO:0008301|DNA binding, bending; GO:0042277|peptide binding"	--	--	865	OXB57807.1	OXB57807.1 hypothetical protein ASZ78_000165 [Callipepla squamata]	sp|Q56K04|CRIP1_BOVIN	sp|Q56K04|CRIP1_BOVIN Cysteine-rich protein 1 OS=Bos taurus GN=CRIP1 PE=3 SV=3	_	_	_	_	_	_
ENSGALG00000002786	0.121064425	0.438234265	-1.773976794	0.000251169	0.000579839	down	yes	0.064237841	0.176622153	0.12233328	0.434933055	0.425547675	0.454222064	10	3594815	3641597	-	PSTPIP1	protein_coding	GO:0006897|endocytosis; GO:0006954|inflammatory response; GO:0007155|cell adhesion; GO:0045087|innate immune response	GO:0001725|stress fiber; GO:0001931|uropod; GO:0005826|actomyosin contractile ring; GO:0005886|plasma membrane; GO:0016020|membrane; GO:0030027|lamellipodium; GO:0032154|cleavage furrow; GO:0048471|perinuclear region of cytoplasm	GO:0003779|actin binding; GO:0019903|protein phosphatase binding; GO:0042802|identical protein binding	ko:K12804|PSTPIP1	ko04621|NOD-like receptor signaling pathway	3212	XP_413733.5	XP_413733.5 proline-serine-threonine phosphatase-interacting protein 1 isoform X2 [Gallus gallus]	sp|P97814|PPIP1_MOUSE	sp|P97814|PPIP1_MOUSE Proline-serine-threonine phosphatase-interacting protein 1 OS=Mus musculus GN=Pstpip1 PE=1 SV=1	9031.ENSGALP00000004390	proline-serine-threonine phosphatase interacting protein 1	_	KOG2398	_	"PF14604.3|SH3_9|Variant SH3 domain|ENSGALT00000103660|m.5281:355-403;PF00018.25|SH3_1|SH3 domain|ENSGALT00000103660|m.5281:354-398;PF00611.20|FCH|Fes/CIP4, and EFC/F-BAR homology domain|ENSGALT00000103660|m.5281:20-92;PF07653.14|SH3_2|Variant SH3 domain|ENSGALT00000103660|m.5281:353-404"
ENSGALG00000002790	0	0.388546719	-5.316676948	2.38E-08	9.06E-08	down	yes	0	0	0	0.477893343	0.393831777	0.293915038	13	9263565	9297986	-	ABLIM3	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0030032|lamellipodium assembly; GO:0030036|actin cytoskeleton organization; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0060271|cilium assembly; GO:1903955|positive regulation of protein targeting to mitochondrion"	GO:0001725|stress fiber; GO:0005737|cytoplasm; GO:0030027|lamellipodium	GO:0003779|actin binding; GO:0046872|metal ion binding	ko:K07520|ABLIM	ko04360|Axon guidance	2602	XP_015149174.1	XP_015149174.1 actin-binding LIM protein 3 isoform X4 [Gallus gallus]	sp|O94929|ABLM3_HUMAN	sp|O94929|ABLM3_HUMAN Actin-binding LIM protein 3 OS=Homo sapiens GN=ABLIM3 PE=1 SV=3	28377.ENSACAP00000015265	"actin binding LIM protein family, member 3"	_	KOG1044	_	PF16182.2|AbLIM_anchor|Putative adherens-junction anchoring region of AbLIM|ENSGALT00000105933|m.8576:273-613;PF00412.19|LIM|LIM domain|ENSGALT00000105933|m.8576:23-76;PF00412.19|LIM|LIM domain|ENSGALT00000105933|m.8576:82-135;PF00412.19|LIM|LIM domain|ENSGALT00000105933|m.8576:151-205;PF00412.19|LIM|LIM domain|ENSGALT00000105933|m.8576:210-263
ENSGALG00000002800	5.52641764	2.676574963	1.043184683	8.04E-09	3.20E-08	up	yes	5.981838618	5.45903239	5.138381911	3.07587683	2.277707187	2.676140872	9	10425071	10442463	+	GRK7	protein_coding	GO:0007165|signal transduction; GO:0007601|visual perception	GO:0016020|membrane	GO:0004703|G protein-coupled receptor kinase activity; GO:0005524|ATP binding; GO:0050254|rhodopsin kinase activity	ko:K00909|GRK1_7	ko04062|Chemokine signaling pathway; ko04144|Endocytosis; ko04744|Phototransduction	1656	XP_426681.2	XP_426681.2 rhodopsin kinase [Gallus gallus]	sp|B6CZ17|GRK7A_XENLA	sp|B6CZ17|GRK7A_XENLA Rhodopsin kinase 1 OS=Xenopus laevis GN=grk7-a PE=1 SV=1	9031.ENSGALP00000004421	G protein-coupled receptor kinase 7	COG0515	KOG0986	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000004430|m.8742:190-437;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000004430|m.8742:192-434;PF00615.16|RGS|Regulator of G protein signaling domain|ENSGALT00000004430|m.8742:56-172
ENSGALG00000002802	0.172772347	0.597009779	-1.731671945	0.000357919	0.000808966	down	yes	0.122823052	0.255152909	0.140341081	0.415797015	0.712448997	0.662783326	26	4359456	4369874	-	PACSIN1	protein_coding	GO:0007015|actin filament organization; GO:0030100|regulation of endocytosis; GO:0045806|negative regulation of endocytosis; GO:0048488|synaptic vesicle endocytosis; GO:0048812|neuron projection morphogenesis; GO:0072657|protein localization to membrane; GO:0097320|plasma membrane tubulation	GO:0005737|cytoplasm; GO:0005768|endosome; GO:0005829|cytosol; GO:0030054|cell junction; GO:0030137|COPI-coated vesicle; GO:0030659|cytoplasmic vesicle membrane; GO:0032587|ruffle membrane; GO:0043209|myelin sheath; GO:0043679|axon terminus	GO:0005543|phospholipid binding; GO:0008092|cytoskeletal protein binding; GO:0042802|identical protein binding	ko:K20123|PACSIN	--	2574	XP_418028.3	XP_418028.3 protein kinase C and casein kinase substrate in neurons protein 1 [Gallus gallus]	sp|A7MBI0|PACN1_BOVIN	sp|A7MBI0|PACN1_BOVIN Protein kinase C and casein kinase substrate in neurons protein 1 OS=Bos taurus GN=PACSIN1 PE=2 SV=1	9031.ENSGALP00000004423	protein kinase C and casein kinase substrate in neurons 1	_	KOG2856	_	"PF00611.20|FCH|Fes/CIP4, and EFC/F-BAR homology domain|ENSGALT00000004432|m.8212:25-99;PF14604.3|SH3_9|Variant SH3 domain|ENSGALT00000004432|m.8212:393-443;PF00018.25|SH3_1|SH3 domain|ENSGALT00000004432|m.8212:392-439;PF07653.14|SH3_2|Variant SH3 domain|ENSGALT00000004432|m.8212:390-443"
ENSGALG00000002804	0.941184279	9.97374885	-3.391784866	1.53E-68	9.58E-67	down	yes	1.17339647	0.798882789	0.851273579	8.953525113	11.03833193	9.929389507	27	7945964	7960601	+	RND2	protein_coding	GO:0007165|signal transduction; GO:0007264|small GTPase mediated signal transduction; GO:0048672|positive regulation of collateral sprouting	GO:0002080|acrosomal membrane; GO:0005769|early endosome	GO:0003924|GTPase activity; GO:0005525|GTP binding; GO:0047485|protein N-terminus binding	ko:K07858|RND2	--	1886	NP_001239052.1	NP_001239052.1 rho-related GTP-binding protein RhoN [Gallus gallus]	sp|P52198|RND2_HUMAN	sp|P52198|RND2_HUMAN Rho-related GTP-binding protein RhoN OS=Homo sapiens GN=RND2 PE=1 SV=2	9031.ENSGALP00000004428	Rho family GTPase 2	COG1100	KOG0393	_	"PF00071.19|Ras|Ras family|ENSGALT00000004437|m.9511:37-203;PF08477.10|Roc|Ras of Complex, Roc, domain of DAPkinase|ENSGALT00000004437|m.9511:37-151;PF00025.18|Arf|ADP-ribosylation factor family|ENSGALT00000004437|m.9511:34-158"
ENSGALG00000002831	6.915579853	15.45538362	-1.159035847	4.94E-25	6.18E-24	down	yes	7.138611752	7.198085336	6.410042471	12.77173045	16.49048253	17.10393788	13	9572001	9637277	+	SH3PXD2B	protein_coding	GO:0001501|skeletal system development; GO:0001654|eye development; GO:0002051|osteoblast fate commitment; GO:0006801|superoxide metabolic process; GO:0007507|heart development; GO:0010628|positive regulation of gene expression; GO:0022617|extracellular matrix disassembly; GO:0040018|positive regulation of multicellular organism growth; GO:0045600|positive regulation of fat cell differentiation; GO:0048705|skeletal system morphogenesis; GO:0051496|positive regulation of stress fiber assembly; GO:0055114|oxidation-reduction process; GO:0060348|bone development; GO:0060378|regulation of brood size; GO:0060612|adipose tissue development; GO:0071800|podosome assembly; GO:0072657|protein localization to membrane; GO:1904179|positive regulation of adipose tissue development; GO:1904888|cranial skeletal system development	GO:0002102|podosome; GO:0005737|cytoplasm; GO:0030054|cell junction; GO:0042995|cell projection	"GO:0010314|phosphatidylinositol-5-phosphate binding; GO:0016176|superoxide-generating NADPH oxidase activator activity; GO:0032266|phosphatidylinositol-3-phosphate binding; GO:0042169|SH2 domain binding; GO:0070273|phosphatidylinositol-4-phosphate binding; GO:0080025|phosphatidylinositol-3,5-bisphosphate binding"	--	--	3757	XP_025010806.1	XP_025010806.1 SH3 and PX domain-containing protein 2B isoform X3 [Gallus gallus]	sp|A1X283|SPD2B_HUMAN	sp|A1X283|SPD2B_HUMAN SH3 and PX domain-containing protein 2B OS=Homo sapiens GN=SH3PXD2B PE=1 SV=3	_	_	_	_	_	PF00018.25|SH3_1|SH3 domain|ENSGALT00000075143|m.8593:214-256;PF00018.25|SH3_1|SH3 domain|ENSGALT00000075143|m.8593:281-325;PF00018.25|SH3_1|SH3 domain|ENSGALT00000075143|m.8593:422-465;PF14604.3|SH3_9|Variant SH3 domain|ENSGALT00000075143|m.8593:212-260;PF14604.3|SH3_9|Variant SH3 domain|ENSGALT00000075143|m.8593:281-329;PF07653.14|SH3_2|Variant SH3 domain|ENSGALT00000075143|m.8593:210-260;PF07653.14|SH3_2|Variant SH3 domain|ENSGALT00000075143|m.8593:285-330;PF07653.14|SH3_2|Variant SH3 domain|ENSGALT00000075143|m.8593:862-916;PF00787.21|PX|PX domain|ENSGALT00000075143|m.8593:47-165
ENSGALG00000002840	0.448882486	0.205036285	1.093544625	0.023951513	0.039125434	up	yes	0.49865384	0.622896953	0.225096666	0.236196411	0.131477181	0.247435263	26	4440323	4474302	+	GRM4	protein_coding	GO:0007196|adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0004930|G protein-coupled receptor activity; GO:0008066|glutamate receptor activity	ko:K04607|GRM4	ko04072|Phospholipase D signaling pathway; ko04080|Neuroactive ligand-receptor interaction; ko04724|Glutamatergic synapse; ko04742|Taste transduction	2754	XP_015154475.1	XP_015154475.1 metabotropic glutamate receptor 4 [Gallus gallus]	sp|Q1ZZH0|GRM4_MACFA	sp|Q1ZZH0|GRM4_MACFA Metabotropic glutamate receptor 4 OS=Macaca fascicularis GN=GRM4 PE=2 SV=1	_	_	_	_	_	PF01094.25|ANF_receptor|Receptor family ligand binding region|ENSGALT00000004481|m.8226:83-486;PF00003.19|7tm_3|7 transmembrane sweet-taste receptor of 3 GCPR|ENSGALT00000004481|m.8226:604-849;PF07562.11|NCD3G|Nine Cysteines Domain of family 3 GPCR|ENSGALT00000004481|m.8226:521-571;PF13458.3|Peripla_BP_6|Periplasmic binding protein|ENSGALT00000004481|m.8226:153-339
ENSGALG00000002846	0.942216076	2.450195833	-1.369412268	1.08E-09	4.63E-09	down	yes	1.096981719	0.962532463	0.767134047	2.002258935	2.624450558	2.723878007	13	9642877	9751876	-	NEURL1B	protein_coding	GO:0007219|Notch signaling pathway; GO:0016567|protein ubiquitination; GO:0070086|ubiquitin-dependent endocytosis	GO:0005769|early endosome	GO:0016740|transferase activity; GO:0016874|ligase activity; GO:0046872|metal ion binding	ko:K01931|NEUR	--	2382	XP_015149317.2	XP_015149317.2 E3 ubiquitin-protein ligase NEURL1B isoform X2 [Gallus gallus]	sp|A8MQ27|NEU1B_HUMAN	sp|A8MQ27|NEU1B_HUMAN E3 ubiquitin-protein ligase NEURL1B OS=Homo sapiens GN=NEURL1B PE=1 SV=1	_	_	_	_	_	PF07177.9|Neuralized|Neuralized|ENSGALT00000104619|m.8598:306-371;PF07177.9|Neuralized|Neuralized|ENSGALT00000104619|m.8598:544-609
ENSGALG00000002877	16.84967114	4.886560986	1.783735637	3.22E-53	1.30E-51	up	yes	14.92580281	17.29678206	18.32642855	4.72883468	5.718215878	4.212632399	18	4994148	5003643	-	LRRC45	protein_coding	--	GO:0005737|cytoplasm; GO:0005815|microtubule organizing center	--	--	--	3156	NP_001073224.1	NP_001073224.1 leucine-rich repeat-containing protein 45 [Gallus gallus]	sp|Q5ZI11|LRC45_CHICK	sp|Q5ZI11|LRC45_CHICK Leucine-rich repeat-containing protein 45 OS=Gallus gallus GN=LRRC45 PE=2 SV=1	9031.ENSGALP00000004528	Leucine-rich repeat-containing protein 45 	_	KOG4308	_	PF13516.3|LRR_6|Leucine Rich repeat|ENSGALT00000004537|m.12735:84-106;PF13516.3|LRR_6|Leucine Rich repeat|ENSGALT00000004537|m.12735:143-161;PF13516.3|LRR_6|Leucine Rich repeat|ENSGALT00000004537|m.12735:171-192;PF00560.30|LRR_1|Leucine Rich Repeat|ENSGALT00000004537|m.12735:173-195
ENSGALG00000002878	3.434128786	15.60037403	-2.180294109	3.26E-80	2.68E-78	down	yes	2.692927154	3.732065229	3.877393977	15.2702119	16.09261272	15.43829746	13	9873168	9892226	+	CREBRF	protein_coding	GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006810|transport; GO:0030968|endoplasmic reticulum unfolded protein response; GO:0032388|positive regulation of intracellular transport; GO:0034976|response to endoplasmic reticulum stress; GO:0042711|maternal behavior; GO:0045732|positive regulation of protein catabolic process; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0051222|positive regulation of protein transport; GO:1900102|negative regulation of endoplasmic reticulum unfolded protein response; GO:1900170|negative regulation of glucocorticoid mediated signaling pathway; GO:1902213|positive regulation of prolactin signaling pathway	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0016604|nuclear body	"GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific"	"ko:K21554|CREBRF,LRF"	--	3194	XP_004944928.1	XP_004944928.1 CREB3 regulatory factor [Gallus gallus]	sp|Q8IUR6|CRERF_HUMAN	sp|Q8IUR6|CRERF_HUMAN CREB3 regulatory factor OS=Homo sapiens GN=CREBRF PE=1 SV=2	9031.ENSGALP00000004529	Putative uncharacterized protein 	_	_	NOG85144	_
ENSGALG00000002888	9.840268763	23.9878964	-1.284672954	1.08E-76	8.07E-75	down	yes	10.43983959	9.210160733	9.870805972	23.66649944	24.75899239	23.53819735	21	3830441	3953755	-	CASZ1	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0045665|negative regulation of neuron differentiation; GO:0045893|positive regulation of transcription, DNA-templated; GO:0060040|retinal bipolar neuron differentiation; GO:0060223|retinal rod cell fate commitment; GO:0060226|negative regulation of retinal cone cell fate commitment; GO:1902870|negative regulation of amacrine cell differentiation"	GO:0005654|nucleoplasm; GO:0005829|cytosol; GO:0043231|intracellular membrane-bounded organelle	GO:0003677|DNA binding; GO:0046872|metal ion binding	--	--	7128	XP_015152639.1	XP_015152639.1 zinc finger protein castor homolog 1 isoform X2 [Gallus gallus]	sp|Q9CWL2|CASZ1_MOUSE	sp|Q9CWL2|CASZ1_MOUSE Zinc finger protein castor homolog 1 OS=Mus musculus GN=Casz1 PE=1 SV=3	_	_	_	_	_	_
ENSGALG00000002931	3.576913964	1.466612071	1.280452284	0.000498399	0.00110034	up	yes	3.309102214	3.608249329	3.813390349	1.914942773	0.906049268	1.578844172	8	4626888	4628302	+	REG4	protein_coding	--	GO:0005576|extracellular region; GO:0005737|cytoplasm	GO:0008201|heparin binding; GO:2001065|mannan binding	--	--	621	NP_001264456.1	NP_001264456.1 regenerating islet-derived protein 4 precursor [Gallus gallus]	sp|Q9BYZ8|REG4_HUMAN	sp|Q9BYZ8|REG4_HUMAN Regenerating islet-derived protein 4 OS=Homo sapiens GN=REG4 PE=1 SV=1	9031.ENSGALP00000004618	"regenerating islet-derived family, member 4"	_	KOG4297	_	PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000004627|m.7028:63-171
ENSGALG00000002942	9.01539522	22.80371076	-1.337839113	2.16E-87	2.02E-85	down	yes	9.000786227	9.132120949	8.913278485	22.43208258	24.31472727	21.66432242	6	8516356	8663452	+	JMJD1C	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated; GO:0007596|blood coagulation; GO:0033169|histone H3-K9 demethylation"	GO:0000785|chromatin; GO:0005622|intracellular; GO:0005634|nucleus; GO:0005654|nucleoplasm	GO:0000976|transcription regulatory region sequence-specific DNA binding; GO:0031490|chromatin DNA binding; GO:0032454|histone demethylase activity (H3-K9 specific); GO:0046872|metal ion binding; GO:0046966|thyroid hormone receptor binding; GO:0051213|dioxygenase activity	ko:K11449|JMJD1C	ko05202|Transcriptional misregulation in cancer	8415	NP_001186475.1	NP_001186475.1 probable JmjC domain-containing histone demethylation protein 2C [Gallus gallus]	sp|Q15652|JHD2C_HUMAN	sp|Q15652|JHD2C_HUMAN Probable JmjC domain-containing histone demethylation protein 2C OS=Homo sapiens GN=JMJD1C PE=1 SV=2	9031.ENSGALP00000004639	jumonji domain containing 1C	_	KOG1356	_	"PF02373.19|JmjC|JmjC domain, hydroxylase|ENSGALT00000004648|m.4413:2373-2470"
ENSGALG00000002952	1.360775066	2.736823915	-1.002772574	3.22E-05	8.49E-05	down	yes	1.553969859	1.498063251	1.030292089	2.803545246	2.879465149	2.527461349	10	3918768	3940587	+	NRG4	protein_coding	GO:0000165|MAPK cascade; GO:0014066|regulation of phosphatidylinositol 3-kinase signaling; GO:0035556|intracellular signal transduction; GO:0038111|interleukin-7-mediated signaling pathway; GO:0038128|ERBB2 signaling pathway; GO:0048015|phosphatidylinositol-mediated signaling; GO:0048513|animal organ development; GO:1901185|negative regulation of ERBB signaling pathway; GO:2000145|regulation of cell motility	GO:0005576|extracellular region; GO:0005615|extracellular space; GO:0005622|intracellular; GO:0005886|plasma membrane; GO:0016021|integral component of membrane	"GO:0004713|protein tyrosine kinase activity; GO:0005088|Ras guanyl-nucleotide exchange factor activity; GO:0005102|signaling receptor binding; GO:0008083|growth factor activity; GO:0046934|phosphatidylinositol-4,5-bisphosphate 3-kinase activity"	ko:K05458|NRG4	ko04012|ErbB signaling pathway	1831	XP_026711723.1	"XP_026711723.1 pro-neuregulin-4, membrane-bound isoform isoform X1 [Athene cunicularia]"	sp|Q8WWG1|NRG4_HUMAN	"sp|Q8WWG1|NRG4_HUMAN Pro-neuregulin-4, membrane-bound isoform OS=Homo sapiens GN=NRG4 PE=1 SV=1"	_	_	_	_	_	_
ENSGALG00000002987	2.591657671	1.026795241	1.327300142	2.41E-09	1.00E-08	up	yes	2.999841246	2.7231734	2.051958367	0.944158752	1.194497175	0.941729796	19	5543842	5551420	+	SERPINF2	protein_coding	GO:0002034|regulation of blood vessel diameter by renin-angiotensin; GO:0002576|platelet degranulation; GO:0006953|acute-phase response; GO:0010033|response to organic substance; GO:0010757|negative regulation of plasminogen activation; GO:0030199|collagen fibril organization; GO:0032967|positive regulation of collagen biosynthetic process; GO:0042730|fibrinolysis; GO:0045597|positive regulation of cell differentiation; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0046330|positive regulation of JNK cascade; GO:0048514|blood vessel morphogenesis; GO:0048661|positive regulation of smooth muscle cell proliferation; GO:0051496|positive regulation of stress fiber assembly; GO:0051918|negative regulation of fibrinolysis; GO:0070374|positive regulation of ERK1 and ERK2 cascade; GO:0071636|positive regulation of transforming growth factor beta production; GO:2000049|positive regulation of cell-cell adhesion mediated by cadherin	GO:0005576|extracellular region; GO:0005577|fibrinogen complex; GO:0005615|extracellular space; GO:0009986|cell surface; GO:0031093|platelet alpha granule lumen; GO:0070062|extracellular exosome; GO:0072562|blood microparticle	GO:0002020|protease binding; GO:0004866|endopeptidase inhibitor activity; GO:0004867|serine-type endopeptidase inhibitor activity; GO:0042803|protein homodimerization activity	"ko:K03983|SERPINF2,AAP"	ko04610|Complement and coagulation cascades	2523	XP_024997830.1	XP_024997830.1 alpha-2-antiplasmin [Gallus gallus]	sp|P08697|A2AP_HUMAN	sp|P08697|A2AP_HUMAN Alpha-2-antiplasmin OS=Homo sapiens GN=SERPINF2 PE=1 SV=3	9031.ENSGALP00000004719	"serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor) [...] "	COG4826	KOG2392	_	PF00079.17|Serpin|Serpin (serine protease inhibitor)|ENSGALT00000105008|m.13823:139-487
ENSGALG00000003005	0.058493692	0.631165741	-3.226654318	1.64E-07	5.73E-07	down	yes	0.083570324	0.091910751	0	0.738718408	0.727138667	0.427640148	10	4055376	4067927	+	CHRNB4	protein_coding	"GO:0007271|synaptic transmission, cholinergic; GO:0007274|neuromuscular synaptic transmission; GO:0035094|response to nicotine; GO:0098655|cation transmembrane transport"	GO:0005892|acetylcholine-gated channel complex; GO:0030054|cell junction; GO:0045211|postsynaptic membrane	GO:0022848|acetylcholine-gated cation-selective channel activity	ko:K04815|CHRNB4	ko04080|Neuroactive ligand-receptor interaction; ko04725|Cholinergic synapse	2522	XP_009096461.2	XP_009096461.2 PREDICTED: neuronal acetylcholine receptor subunit beta-4 [Serinus canaria]	sp|P26153|ACHB4_CHICK	sp|P26153|ACHB4_CHICK Neuronal acetylcholine receptor subunit beta-4 (Fragment) OS=Gallus gallus GN=CHRNB4 PE=1 SV=1	9031.ENSGALP00000004740	Neuronal acetylcholine receptor subunit beta-4 Precursor; Fragment (Neuronal acetylcholine r [...] 	_	KOG3645	_	PF02932.13|Neur_chan_memb|Neurotransmitter-gated ion-channel transmembrane region|ENSGALT00000039804|m.5308:238-475;PF02931.20|Neur_chan_LBD|Neurotransmitter-gated ion-channel ligand binding domain|ENSGALT00000039804|m.5308:26-231
ENSGALG00000003031	7.837319292	3.123226536	1.32455082	2.94E-21	2.98E-20	up	yes	7.424466497	8.097581102	7.989910276	3.164028103	3.603331767	2.602319738	19	5561964	5568555	-	SMYD4	protein_coding	--	--	GO:0008168|methyltransferase activity; GO:0046872|metal ion binding	--	--	2397	NP_001025886.1	NP_001025886.1 SET and MYND domain-containing protein 4 [Gallus gallus]	sp|Q5F3V0|SMYD4_CHICK	sp|Q5F3V0|SMYD4_CHICK SET and MYND domain-containing protein 4 OS=Gallus gallus GN=SMYD4 PE=2 SV=1	9031.ENSGALP00000004786	SET and MYND domain-containing protein 4 	_	KOG2084	_	PF00856.25|SET|SET domain|ENSGALT00000004795|m.13826:245-573;PF01753.15|zf-MYND|MYND finger|ENSGALT00000004795|m.13826:299-338
ENSGALG00000003033	4.290107035	8.747914032	-1.026214718	1.12E-19	1.03E-18	down	yes	4.154688359	3.837228806	4.878403941	7.809575427	9.25528044	9.17888623	18	5836752	5890639	+	STXBP4	protein_coding	GO:0006605|protein targeting; GO:0006974|cellular response to DNA damage stimulus; GO:0008286|insulin receptor signaling pathway; GO:0010838|positive regulation of keratinocyte proliferation; GO:0050821|protein stabilization; GO:0061178|regulation of insulin secretion involved in cellular response to glucose stimulus; GO:1902808|positive regulation of cell cycle G1/S phase transition; GO:1904659|glucose transmembrane transport	GO:0005737|cytoplasm; GO:0070062|extracellular exosome	GO:0019905|syntaxin binding	"ko:K15302|STXBP4,SYNIP"	--	3885	XP_004946214.1	XP_004946214.1 syntaxin-binding protein 4 isoform X1 [Gallus gallus]	sp|Q9WV89|STXB4_MOUSE	sp|Q9WV89|STXB4_MOUSE Syntaxin-binding protein 4 OS=Mus musculus GN=Stxbp4 PE=1 SV=1	9031.ENSGALP00000004791	syntaxin binding protein 4	_	_	NOG72384	PF00595.21|PDZ|PDZ domain (Also known as DHR or GLGF)|ENSGALT00000096719|m.12776:43-119;PF00595.21|PDZ|PDZ domain (Also known as DHR or GLGF)|ENSGALT00000096719|m.12776:211-277;PF00397.23|WW|WW domain|ENSGALT00000096719|m.12776:681-710
ENSGALG00000003034	2.507451419	1.048825771	1.249498724	0.004708883	0.008867644	up	yes	2.51408775	2.534580568	2.473685939	0.98507245	0.952882828	1.208522034	21	4105253	4109012	-	SS2	protein_coding	--	GO:0005576|extracellular region	GO:0005179|hormone activity	--	--	503	ABB86711.1	ABB86711.1 somatostatin II precursor [Gallus gallus]	sp|Q9W7E9|SMS2_PROAN	sp|Q9W7E9|SMS2_PROAN Somatostatin-2 OS=Protopterus annectens GN=sst2 PE=3 SV=1	9031.ENSGALP00000004793	 	_	_	NOG40146	PF03002.12|Somatostatin|Somatostatin/Cortistatin family|ENSGALT00000004802|m.4060:115-132
ENSGALG00000003035	11.08529105	4.518061047	1.292982199	1.62E-10	7.56E-10	up	yes	11.8436514	9.262693857	12.1495279	5.642959486	3.26847543	4.642748226	8	4686653	4690632	+	FAM78B	protein_coding	--	--	--	--	--	1001	XP_001232254.1	XP_001232254.1 protein FAM78B isoform X1 [Gallus gallus]	sp|Q5VT40|FA78B_HUMAN	sp|Q5VT40|FA78B_HUMAN Protein FAM78B OS=Homo sapiens GN=FAM78B PE=2 SV=1	9031.ENSGALP00000004794	"family with sequence similarity 78, member B"	_	_	NOG44943	_
ENSGALG00000003058	1.653566263	0.748173014	1.13368032	1.18E-06	3.74E-06	up	yes	1.56526206	1.814890747	1.580545982	0.657232173	0.842203309	0.745083561	28	3777894	3786314	+	ENSGALG00000003058	protein_coding	GO:0050919|negative chemotaxis	GO:0005615|extracellular space; GO:0005886|plasma membrane; GO:0016021|integral component of membrane	--	"ko:K06521|SEMA4,CD100"	ko04360|Axon guidance	2895	XP_015155616.1	XP_015155616.1 homer protein homolog 3 isoform X2 [Gallus gallus]	sp|Q9YHX4|SEM4E_DANRE	sp|Q9YHX4|SEM4E_DANRE Semaphorin-4E OS=Danio rerio GN=sema4e PE=2 SV=1	_	_	_	_	_	PF01403.16|Sema|Sema domain|ENSGALT00000004831|m.10320:51-478;PF01437.22|PSI|Plexin repeat|ENSGALT00000004831|m.10320:500-529
ENSGALG00000003073	15.81091421	45.8870728	-1.536569177	2.20E-116	4.57E-114	down	yes	15.14396911	16.93215539	15.35661813	44.41063935	47.49701301	45.75356605	6	9336702	9386648	+	RHOBTB1	protein_coding	GO:0007264|small GTPase mediated signal transduction; GO:0051056|regulation of small GTPase mediated signal transduction	GO:0005829|cytosol; GO:0005886|plasma membrane	GO:0003924|GTPase activity; GO:0005525|GTP binding	ko:K07868|RHOBTB1_2	ko04120|Ubiquitin mediated proteolysis	3144	NP_001186537.1	NP_001186537.1 rho-related BTB domain-containing protein 1 [Gallus gallus]	sp|O94844|RHBT1_HUMAN	sp|O94844|RHBT1_HUMAN Rho-related BTB domain-containing protein 1 OS=Homo sapiens GN=RHOBTB1 PE=2 SV=2	59729.ENSTGUP00000005477	Rho-related BTB domain-containing protein 1 [Taeniopygia guttata]	COG1100	KOG0393	_	"PF00651.28|BTB|BTB/POZ domain|ENSGALT00000004854|m.4441:474-579;PF00071.19|Ras|Ras family|ENSGALT00000004854|m.4441:16-207;PF08477.10|Roc|Ras of Complex, Roc, domain of DAPkinase|ENSGALT00000004854|m.4441:16-143"
ENSGALG00000003096	10.93784285	27.20679773	-1.313850702	2.21E-35	4.49E-34	down	yes	12.32637695	10.24390373	10.24324787	23.90914364	28.7410307	28.97021886	20	2208406	2258331	-	CBFA2T2	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006351|transcription, DNA-templated; GO:0010976|positive regulation of neuron projection development; GO:0010977|negative regulation of neuron projection development; GO:0030855|epithelial cell differentiation; GO:0045746|negative regulation of Notch signaling pathway; GO:0045892|negative regulation of transcription, DNA-templated; GO:0060575|intestinal epithelial cell differentiation"	GO:0005634|nucleus	GO:0003700|DNA-binding transcription factor activity; GO:0003714|transcription corepressor activity; GO:0046872|metal ion binding	--	--	2054	NP_001011689.1	NP_001011689.1 protein CBFA2T2 [Gallus gallus]	sp|O70374|MTG8R_MOUSE	sp|O70374|MTG8R_MOUSE Protein CBFA2T2 OS=Mus musculus GN=Cbfa2t2 PE=1 SV=3	9031.ENSGALP00000039582	"core-binding factor, runt domain, alpha subunit 2; translocated to, 2 "	_	_	NOG68841	PF08788.8|NHR2|NHR2 domain like|ENSGALT00000099282|m.2890:301-364;PF07531.11|TAFH|NHR1 homology to TAF|ENSGALT00000099282|m.2890:87-175;PF01753.15|zf-MYND|MYND finger|ENSGALT00000099282|m.2890:476-512
ENSGALG00000003172	7.073752404	24.22819481	-1.774696563	9.97E-84	8.79E-82	down	yes	6.387930689	7.477384315	7.355942209	23.74002956	25.58167959	23.36287528	6	9839922	9859361	+	SLC16A9	protein_coding	GO:0015718|monocarboxylic acid transport	GO:0005887|integral component of plasma membrane	GO:0008028|monocarboxylic acid transmembrane transporter activity; GO:0015293|symporter activity	ko:K08186|SLC16A9	--	2519	XP_015143617.2	XP_015143617.2 monocarboxylate transporter 9 isoform X1 [Gallus gallus]	sp|Q5ZJU0|MOT9_CHICK	sp|Q5ZJU0|MOT9_CHICK Monocarboxylate transporter 9 OS=Gallus gallus GN=SLC16A9 PE=2 SV=1	9031.ENSGALP00000005024	Monocarboxylate transporter 9 (MCT 9)(Solute carrier family 16 member 9); Proton-linked mono [...] 	COG0477	KOG2504	_	PF07690.13|MFS_1|Major Facilitator Superfamily|ENSGALT00000098307|m.4463:21-263;PF07690.13|MFS_1|Major Facilitator Superfamily|ENSGALT00000098307|m.4463:308-478
ENSGALG00000003213	9.789657884	4.791865826	1.029136292	2.04E-11	1.02E-10	up	yes	8.925420634	10.03549642	10.4080566	6.084508904	4.381706926	3.909381647	1	51206946	51218711	+	LGALS2	protein_coding	--	--	GO:0016936|galactoside binding; GO:0030246|carbohydrate binding	ko:K10090|LGALS2	--	1567	XP_015143897.1	XP_015143897.1 galectin-2 isoform X1 [Gallus gallus]	sp|P05162|LEG2_HUMAN	sp|P05162|LEG2_HUMAN Galectin-2 OS=Homo sapiens GN=LGALS2 PE=1 SV=3	9031.ENSGALP00000005081	"lectin, galactoside-binding, soluble, 2"	_	KOG3587	_	PF00337.19|Gal-bind_lectin|Galactoside-binding lectin|ENSGALT00000093316|m.1437:10-126
ENSGALG00000003227	11.34896366	26.04301444	-1.197619091	9.57E-30	1.48E-28	down	yes	13.26000918	10.56974903	10.21713278	24.15110608	28.25703651	25.72090074	18	6309446	6396232	+	RAB11FIP4	protein_coding	GO:0000910|cytokinesis; GO:0003407|neural retina development; GO:0006810|transport; GO:0016032|viral process; GO:1903452|positive regulation of G1 to G0 transition	GO:0005615|extracellular space; GO:0005768|endosome; GO:0005815|microtubule organizing center; GO:0005819|spindle; GO:0030139|endocytic vesicle; GO:0030496|midbody; GO:0032154|cleavage furrow; GO:0043231|intracellular membrane-bounded organelle; GO:0048471|perinuclear region of cytoplasm; GO:0055038|recycling endosome membrane	GO:0005509|calcium ion binding; GO:0017137|Rab GTPase binding; GO:0030306|ADP-ribosylation factor binding; GO:0042803|protein homodimerization activity	ko:K12485|RAB11FIP3_4	ko04144|Endocytosis	2117	XP_004946223.2	XP_004946223.2 rab11 family-interacting protein 4 isoform X1 [Gallus gallus]	sp|Q86YS3|RFIP4_HUMAN	sp|Q86YS3|RFIP4_HUMAN Rab11 family-interacting protein 4 OS=Homo sapiens GN=RAB11FIP4 PE=1 SV=1	_	_	_	_	_	PF09457.7|RBD-FIP|FIP domain|ENSGALT00000099188|m.12794:522-562
ENSGALG00000003242	0.664993112	0.270925232	1.264686571	0.007561158	0.013678915	up	yes	0.662402263	0.529826089	0.802750985	0.362416598	0.226253446	0.224105653	22	2578576	2581509	-	STAR	protein_coding	GO:0006694|steroid biosynthetic process; GO:0008203|cholesterol metabolic process; GO:0008211|glucocorticoid metabolic process; GO:0044255|cellular lipid metabolic process; GO:0070859|positive regulation of bile acid biosynthetic process	GO:0005739|mitochondrion	GO:0015485|cholesterol binding; GO:0120020|cholesterol transfer activity	ko:K16931|STAR	ko04913|Ovarian steroidogenesis; ko04925|Aldosterone synthesis and secretion	1750	NP_990017.1	"NP_990017.1 steroidogenic acute regulatory protein, mitochondrial precursor [Gallus gallus]"	sp|Q9DG09|STAR_CHICK	"sp|Q9DG09|STAR_CHICK Steroidogenic acute regulatory protein, mitochondrial OS=Gallus gallus GN=STAR PE=2 SV=1"	9031.ENSGALP00000005119	"Steroidogenic acute regulatory protein, mitochondrial Precursor (StAR)(StARD1); Plays a key  [...] "	_	KOG3845	_	PF01852.16|START|START domain|ENSGALT00000005128|m.4739:78-277
ENSGALG00000003248	47.14221	17.47948243	1.430837795	2.27E-59	1.10E-57	up	yes	41.95004844	48.67630574	50.80027583	15.61825561	19.43818303	17.38200865	Z	9801245	9816238	+	SUB1	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0060261|positive regulation of transcription initiation from RNA polymerase II promoter"	GO:0005634|nucleus; GO:0005667|transcription factor complex	GO:0003677|DNA binding; GO:0003713|transcription coactivator activity	--	--	3689	NP_001008479.1	NP_001008479.1 activated RNA polymerase II transcriptional coactivator p15 [Gallus gallus]	sp|Q5ZK63|TCP4_CHICK	sp|Q5ZK63|TCP4_CHICK Activated RNA polymerase II transcriptional coactivator p15 OS=Gallus gallus GN=SUB1 PE=2 SV=1	_	_	_	_	_	PF02229.13|PC4|Transcriptional Coactivator p15 (PC4)|ENSGALT00000005135|m.10625:73-124
ENSGALG00000003258	0.849331442	2.301544363	-1.427570463	1.77E-07	6.16E-07	down	yes	0.973957285	1.017601516	0.556435526	2.161478382	2.677115997	2.066038712	11	2479810	2493248	-	DNAAF1	protein_coding	GO:0044458|motile cilium assembly; GO:0060271|cilium assembly	GO:0005930|axoneme	GO:0070840|dynein complex binding	"ko:K19750|DNAAF1,LRRC50,ODA7"	--	1949	XP_015728964.1	"XP_015728964.1 PREDICTED: dynein assembly factor 1, axonemal [Coturnix japonica]"	sp|B6D5P1|DAAF1_PERPL	"sp|B6D5P1|DAAF1_PERPL Dynein assembly factor 1, axonemal OS=Peromyscus polionotus GN=Dnaaf1 PE=2 SV=1"	_	_	_	_	_	PF14580.3|LRR_9|Leucine-rich repeat|ENSGALT00000005159|m.6410:204-339
ENSGALG00000003282	25.19833829	55.9661114	-1.150910248	4.02E-71	2.73E-69	down	yes	25.16834495	24.60906376	25.81760616	54.63964519	55.08980403	58.16888497	27	7694496	7699792	-	STAT5B	protein_coding	"GO:0001553|luteinization; GO:0001779|natural killer cell differentiation; GO:0006351|transcription, DNA-templated; GO:0007259|receptor signaling pathway via JAK-STAT; GO:0007565|female pregnancy; GO:0007595|lactation; GO:0008284|positive regulation of cell population proliferation; GO:0019218|regulation of steroid metabolic process; GO:0019221|cytokine-mediated signaling pathway; GO:0019915|lipid storage; GO:0030155|regulation of cell adhesion; GO:0030856|regulation of epithelial cell differentiation; GO:0040018|positive regulation of multicellular organism growth; GO:0042104|positive regulation of activated T cell proliferation; GO:0042448|progesterone metabolic process; GO:0043029|T cell homeostasis; GO:0043066|negative regulation of apoptotic process; GO:0045086|positive regulation of interleukin-2 biosynthetic process; GO:0045579|positive regulation of B cell differentiation; GO:0045647|negative regulation of erythrocyte differentiation; GO:0045648|positive regulation of erythrocyte differentiation; GO:0045931|positive regulation of mitotic cell cycle; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0046543|development of secondary female sexual characteristics; GO:0046544|development of secondary male sexual characteristics; GO:0050729|positive regulation of inflammatory response; GO:0060397|growth hormone receptor signaling pathway via JAK-STAT; GO:0071363|cellular response to growth factor stimulus; GO:0071364|cellular response to epidermal growth factor stimulus"	GO:0005634|nucleus; GO:0005737|cytoplasm	GO:0003677|DNA binding; GO:0003682|chromatin binding; GO:0003700|DNA-binding transcription factor activity; GO:0046983|protein dimerization activity	ko:K11224|STAT5B	ko04012|ErbB signaling pathway; ko04062|Chemokine signaling pathway; ko04630|Jak-STAT signaling pathway; ko04658|Th1 and Th2 cell differentiation; ko04659|Th17 cell differentiation; ko04917|Prolactin signaling pathway; ko04933|AGE-RAGE signaling pathway in diabetic complications; ko05161|Hepatitis B; ko05162|Measles; ko05166|HTLV-I infection; ko05200|Pathways in cancer; ko05203|Viral carcinogenesis; ko05220|Chronic myeloid leukemia; ko05221|Acute myeloid leukemia; ko05223|Non-small cell lung cancer	2887	XP_010722974.1	XP_010722974.1 PREDICTED: signal transducer and activator of transcription 5B isoform X2 [Meleagris gallopavo]	sp|Q9TUM3|STA5B_BOVIN	sp|Q9TUM3|STA5B_BOVIN Signal transducer and activator of transcription 5B OS=Bos taurus GN=STAT5B PE=2 SV=2	9031.ENSGALP00000039101	signal transducer and activator of transcription 5B 	_	KOG3667	_	"PF02864.12|STAT_bind|STAT protein, DNA binding domain|ENSGALT00000005191|m.9412:336-564;PF01017.17|STAT_alpha|STAT protein, all-alpha domain|ENSGALT00000005191|m.9412:152-340;PF02865.14|STAT_int|STAT protein, protein interaction domain|ENSGALT00000005191|m.9412:54-133;PF00017.21|SH2|SH2 domain|ENSGALT00000005191|m.9412:577-650"
ENSGALG00000003295	0.392387428	0.965566198	-1.277654541	1.25E-06	3.94E-06	down	yes	0.387760328	0.316798347	0.472603608	1.100166029	0.819368776	0.977163788	Z	10140727	10313424	-	ADAMTS12	protein_coding	GO:0007160|cell-matrix adhesion; GO:0016477|cell migration; GO:0030167|proteoglycan catabolic process; GO:0032331|negative regulation of chondrocyte differentiation; GO:0050727|regulation of inflammatory response; GO:0051603|proteolysis involved in cellular protein catabolic process; GO:0071347|cellular response to interleukin-1; GO:0071356|cellular response to tumor necrosis factor; GO:0071773|cellular response to BMP stimulus; GO:1901509|regulation of endothelial tube morphogenesis; GO:1902203|negative regulation of hepatocyte growth factor receptor signaling pathway; GO:1902548|negative regulation of cellular response to vascular endothelial growth factor stimulus; GO:2001113|negative regulation of cellular response to hepatocyte growth factor stimulus	GO:0031012|extracellular matrix	GO:0004222|metalloendopeptidase activity; GO:0008270|zinc ion binding	ko:K08626|ADAMTS12	--	4743	XP_003643023.2	XP_003643023.2 A disintegrin and metalloproteinase with thrombospondin motifs 12 isoform X1 [Gallus gallus]	sp|P58397|ATS12_HUMAN	sp|P58397|ATS12_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 12 OS=Homo sapiens GN=ADAMTS12 PE=1 SV=2	59729.ENSTGUP00000002001	A disintegrin and metalloproteinase with thrombospondin motifs 12 Precursor (ADAMTS-12)(ADAM [...] 	_	KOG3538	_	PF05986.11|ADAM_spacer1|ADAM-TS Spacer 1|ENSGALT00000101261|m.10629:709-818;PF01562.16|Pep_M12B_propep|Reprolysin family propeptide|ENSGALT00000101261|m.10629:49-191;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000101261|m.10629:553-602;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000101261|m.10629:838-889;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000101261|m.10629:896-922;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000101261|m.10629:958-1003;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000101261|m.10629:1338-1383;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000101261|m.10629:1447-1498;PF01421.16|Reprolysin|Reprolysin (M12B) family zinc metalloprotease|ENSGALT00000101261|m.10629:252-462;PF13688.3|Reprolysin_5|Metallo-peptidase family M12|ENSGALT00000101261|m.10629:251-429;PF13582.3|Reprolysin_3|Metallo-peptidase family M12B Reprolysin-like|ENSGALT00000101261|m.10629:276-409
ENSGALG00000003319	1.835652316	0.408768114	2.139907301	1.88E-13	1.12E-12	up	yes	1.843798584	1.942129884	1.72102848	0.459104934	0.390284406	0.376915002	18	6639244	6650095	+	ADAP2	protein_coding	GO:0007507|heart development	GO:0005737|cytoplasm; GO:0005740|mitochondrial envelope; GO:0005829|cytosol; GO:0005886|plasma membrane	"GO:0005096|GTPase activator activity; GO:0005545|1-phosphatidylinositol binding; GO:0005546|phosphatidylinositol-4,5-bisphosphate binding; GO:0005547|phosphatidylinositol-3,4,5-trisphosphate binding; GO:0043325|phosphatidylinositol-3,4-bisphosphate binding; GO:0043533|inositol 1,3,4,5 tetrakisphosphate binding; GO:0046872|metal ion binding"	--	--	2029	XP_415661.1	XP_415661.1 arf-GAP with dual PH domain-containing protein 2 [Gallus gallus]	sp|Q9JK15|ADAP2_RAT	sp|Q9JK15|ADAP2_RAT Arf-GAP with dual PH domain-containing protein 2 OS=Rattus norvegicus GN=Adap2 PE=1 SV=1	9031.ENSGALP00000005249	"centaurin, alpha 2"	COG5347	KOG0703	_	PF01412.15|ArfGap|Putative GTPase activating protein for Arf|ENSGALT00000078875|m.12801:19-131;PF00169.26|PH|PH domain|ENSGALT00000078875|m.12801:144-239;PF00169.26|PH|PH domain|ENSGALT00000078875|m.12801:265-368
ENSGALG00000003323	2.729161932	19.18437525	-2.808877141	8.44E-116	1.67E-113	down	yes	2.744847415	2.18084474	3.261793642	20.67191425	16.28760436	20.59360715	11	2532308	2633462	-	NECAB2	protein_coding	GO:0007275|multicellular organism development; GO:0030154|cell differentiation; GO:0030308|negative regulation of cell growth; GO:0043065|positive regulation of apoptotic process	--	GO:0008083|growth factor activity	--	--	3181	XP_414073.2	XP_414073.2 oxidative stress-induced growth inhibitor 1 [Gallus gallus]	sp|Q9UJX0|OSGI1_HUMAN	sp|Q9UJX0|OSGI1_HUMAN Oxidative stress-induced growth inhibitor 1 OS=Homo sapiens GN=OSGIN1 PE=1 SV=3	9031.ENSGALP00000005253	oxidative stress induced growth inhibitor 1	_	_	NOG68947	_
ENSGALG00000003340	1.213430162	3.492334515	-1.517385136	4.41E-17	3.41E-16	down	yes	1.054480833	1.280523497	1.305286155	3.737102437	3.655645309	3.084255798	17	7130052	7137248	-	GBGT1	protein_coding	GO:0005975|carbohydrate metabolic process; GO:0006486|protein glycosylation; GO:0009247|glycolipid biosynthetic process; GO:0030259|lipid glycosylation	GO:0000139|Golgi membrane; GO:0005794|Golgi apparatus; GO:0016021|integral component of membrane; GO:0031982|vesicle	GO:0046872|metal ion binding; GO:0047277|globoside alpha-N-acetylgalactosaminyltransferase activity	ko:K00722|GBGT1	ko00603|Glycosphingolipid biosynthesis - globo and isoglobo series; ko01100|Metabolic pathways	3198	XP_015734861.1	"XP_015734861.1 PREDICTED: globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 [Coturnix japonica]"	sp|Q5ZLK4|GBGT1_CHICK	"sp|Q5ZLK4|GBGT1_CHICK Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 OS=Gallus gallus GN=GBGT1 PE=2 SV=1"	9031.ENSGALP00000005275	"Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.-)(Forssman glycolipid syn [...] "	_	_	NOG43612	PF03414.10|Glyco_transf_6|Glycosyltransferase family 6|ENSGALT00000005285|m.12178:87-373
ENSGALG00000003353	7.64607711	21.029498	-1.458423017	2.45E-45	7.61E-44	down	yes	8.101017952	7.064420063	7.772793316	19.08703706	23.87263471	20.12882225	Z	10460141	10544706	+	RAI14	protein_coding	GO:0007283|spermatogenesis; GO:0030154|cell differentiation	GO:0001650|fibrillar center; GO:0005634|nucleus; GO:0005739|mitochondrion; GO:0005829|cytosol; GO:0005856|cytoskeleton; GO:0005938|cell cortex; GO:0030054|cell junction	--	--	--	3057	XP_004937233.1	XP_004937233.1 ankycorbin isoform X5 [Gallus gallus]	sp|Q9EP71|RAI14_MOUSE	sp|Q9EP71|RAI14_MOUSE Ankycorbin OS=Mus musculus GN=Rai14 PE=1 SV=1	9031.ENSGALP00000005295	retinoic acid induced 14	COG0666	KOG0504	_	PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000005305|m.10642:23-116;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000005305|m.10642:118-182;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000005305|m.10642:156-245;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000005305|m.10642:43-93;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000005305|m.10642:105-159;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000005305|m.10642:151-189;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000005305|m.10642:171-224;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000005305|m.10642:23-70;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000005305|m.10642:67-106;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000005305|m.10642:87-138;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000005305|m.10642:130-172;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000005305|m.10642:163-205;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000005305|m.10642:53-83;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000005305|m.10642:86-117;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000005305|m.10642:119-149;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000005305|m.10642:151-183;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000005305|m.10642:184-215;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000005305|m.10642:119-146;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000005305|m.10642:155-179;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000005305|m.10642:184-212
ENSGALG00000003358	52.62138159	21.63496509	1.281891793	1.51E-102	1.96E-100	up	yes	52.08325252	54.0042708	51.77662146	20.80145029	21.97041385	22.13303113	21	4200628	4206138	+	UBIAD1	protein_coding	"GO:0001885|endothelial cell development; GO:0006744|ubiquinone biosynthetic process; GO:0009234|menaquinone biosynthetic process; GO:0032194|ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate; GO:0042371|vitamin K biosynthetic process; GO:0072358|cardiovascular system development"	GO:0005739|mitochondrion; GO:0005783|endoplasmic reticulum; GO:0005789|endoplasmic reticulum membrane; GO:0030173|integral component of Golgi membrane	GO:0004659|prenyltransferase activity; GO:0016209|antioxidant activity	--	--	4421	XP_015152380.1	XP_015152380.1 ubiA prenyltransferase domain-containing protein 1 isoform X1 [Gallus gallus]	sp|Q5ZKS8|UBIA1_CHICK	sp|Q5ZKS8|UBIA1_CHICK UbiA prenyltransferase domain-containing protein 1 OS=Gallus gallus GN=UBIAD1 PE=2 SV=1	9031.ENSGALP00000005301	UbiA prenyltransferase domain-containing protein 1 	COG1575	KOG4581	_	PF01040.15|UbiA|UbiA prenyltransferase family|ENSGALT00000005311|m.4068:88-342
ENSGALG00000003360	0.853245726	0.373867696	1.16916213	0.004074911	0.007751441	up	yes	0.95298936	0.833971199	0.77277662	0.370028615	0.328271059	0.423303414	13	11124638	11127201	-	ARL10	protein_coding	GO:0007264|small GTPase mediated signal transduction	GO:0005622|intracellular	GO:0005525|GTP binding	ko:K07958|ARL10	--	1714	NP_001264643.1	NP_001264643.1 ADP-ribosylation factor-like protein 10 [Gallus gallus]	sp|Q8N8L6|ARL10_HUMAN	sp|Q8N8L6|ARL10_HUMAN ADP-ribosylation factor-like protein 10 OS=Homo sapiens GN=ARL10 PE=2 SV=1	_	_	_	_	_	"PF00025.18|Arf|ADP-ribosylation factor family|ENSGALT00000005313|m.8740:75-217;PF08477.10|Roc|Ras of Complex, Roc, domain of DAPkinase|ENSGALT00000005313|m.8740:76-185;PF04670.9|Gtr1_RagA|Gtr1/RagA G protein conserved region|ENSGALT00000005313|m.8740:76-199;PF00071.19|Ras|Ras family|ENSGALT00000005313|m.8740:76-197;PF09439.7|SRPRB|Signal recognition particle receptor beta subunit|ENSGALT00000005313|m.8740:74-198;PF01926.20|MMR_HSR1|50S ribosome-binding GTPase|ENSGALT00000005313|m.8740:75-182"
ENSGALG00000003374	16.44994636	34.57123271	-1.071029664	1.02E-50	3.78E-49	down	yes	15.39258216	17.35722639	16.60003052	33.49559679	35.99076689	34.22733446	11	3254661	3298212	+	ESRP2	protein_coding	GO:0006397|mRNA processing; GO:0008380|RNA splicing; GO:0043484|regulation of RNA splicing	GO:0005634|nucleus	GO:0003729|mRNA binding	ko:K14947|ESRP1_2	--	3685	NP_001025737.1	NP_001025737.1 epithelial splicing regulatory protein 2 [Gallus gallus]	sp|Q5ZLR4|ESRP2_CHICK	sp|Q5ZLR4|ESRP2_CHICK Epithelial splicing regulatory protein 2 OS=Gallus gallus GN=ESRP2 PE=2 SV=1	9031.ENSGALP00000005323	Epithelial splicing regulatory protein 2 (RNA-binding protein 35B)(RNA-binding motif protein [...] 	_	KOG1365	_	_
ENSGALG00000003377	4.049659084	9.169580736	-1.177069682	2.53E-22	2.72E-21	down	yes	3.925220022	3.983637337	4.240119893	9.075668174	9.437250536	8.995823499	13	11137633	11143985	-	SIMC1	protein_coding	--	--	GO:0032184|SUMO polymer binding	--	--	2190	XP_015149369.1	XP_015149369.1 SUMO-interacting motif-containing protein 1 isoform X2 [Gallus gallus]	sp|Q8NDZ2|SIMC1_HUMAN	sp|Q8NDZ2|SIMC1_HUMAN SUMO-interacting motif-containing protein 1 OS=Homo sapiens GN=SIMC1 PE=1 SV=3	9031.ENSGALP00000005327	chromosome 5 open reading frame 25	_	_	NOG41417	_
ENSGALG00000003420	3.062363447	1.262836264	1.271302046	8.80E-13	4.94E-12	up	yes	3.296534151	3.148660704	2.741895486	1.172959113	1.282625037	1.332924643	23	5358716	5363244	+	ZBTB8A	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated"	GO:0005634|nucleus	GO:0003677|DNA binding; GO:0046872|metal ion binding	ko:K10495|ZBTB8	--	2450	XP_024998835.1	XP_024998835.1 zinc finger and BTB domain-containing protein 8A-like [Gallus gallus]	sp|Q0VCJ6|ZBT8A_BOVIN	sp|Q0VCJ6|ZBT8A_BOVIN Zinc finger and BTB domain-containing protein 8A OS=Bos taurus GN=ZBTB8A PE=2 SV=1	_	_	_	_	_	PF00651.28|BTB|BTB/POZ domain|ENSGALT00000106512|m.5757:14-121;PF11822.5|DUF3342|Domain of unknown function (DUF3342)|ENSGALT00000106512|m.5757:31-114
ENSGALG00000003433	1.757153808	4.324727799	-1.294513789	1.24E-14	8.06E-14	down	yes	1.538796248	2.058120437	1.674544738	4.834062854	3.892289954	4.247830589	11	3459157	3474477	+	DPEP2	protein_coding	--	GO:0031225|anchored component of membrane	GO:0008235|metalloexopeptidase activity; GO:0008238|exopeptidase activity; GO:0008239|dipeptidyl-peptidase activity; GO:0016805|dipeptidase activity; GO:0046872|metal ion binding	ko:K01273|DPEP	--	3116	XP_015147853.1	XP_015147853.1 dipeptidase 2 isoform X1 [Gallus gallus]	sp|Q5M872|DPEP2_RAT	sp|Q5M872|DPEP2_RAT Dipeptidase 2 OS=Rattus norvegicus GN=Dpep2 PE=2 SV=1	9031.ENSGALP00000005425	dipeptidase 2	COG2355	KOG4127	_	PF01244.18|Peptidase_M19|Membrane dipeptidase (Peptidase family M19)|ENSGALT00000005435|m.6445:35-356
ENSGALG00000003435	0.070499025	0.690427777	-3.121193087	8.96E-05	0.000221669	down	yes	0	0.051373873	0.160123202	0.672076159	0.290971939	1.108235234	26	4946576	4950586	-	PGC	protein_coding	GO:0007586|digestion	GO:0005576|extracellular region	GO:0004190|aspartic-type endopeptidase activity	ko:K01377|PGC	--	1504	NP_990208.1	NP_990208.1 gastricsin precursor [Gallus gallus]	sp|Q9GMY3|PEPC_RHIFE	sp|Q9GMY3|PEPC_RHIFE Gastricsin OS=Rhinolophus ferrumequinum GN=PGC PE=2 SV=1	9031.ENSGALP00000005433	progastricsin (pepsinogen C) 	_	KOG1339	_	PF00026.20|Asp|Eukaryotic aspartyl protease|ENSGALT00000005443|m.8275:137-452;PF14543.3|TAXi_N|Xylanase inhibitor N-terminal|ENSGALT00000005443|m.8275:138-190;PF07966.9|A1_Propeptide|A1 Propeptide|ENSGALT00000005443|m.8275:82-110;PF14541.3|TAXi_C|Xylanase inhibitor C-terminal|ENSGALT00000005443|m.8275:340-451
ENSGALG00000003443	1.679925667	0.787234176	1.083884327	0.008161753	0.014669687	up	yes	2.572089426	1.320100741	1.147586834	0.566670827	1.220702361	0.57432934	8	5849184	5851743	+	LRRC52	protein_coding	GO:0006813|potassium ion transport; GO:0022414|reproductive process; GO:0071805|potassium ion transmembrane transport; GO:1903818|positive regulation of voltage-gated potassium channel activity	GO:0008076|voltage-gated potassium channel complex	GO:0005249|voltage-gated potassium channel activity; GO:0005267|potassium channel activity; GO:0044325|ion channel binding; GO:0099104|potassium channel activator activity	--	--	1434	XP_003208619.1	XP_003208619.1 PREDICTED: leucine-rich repeat-containing protein 52 [Meleagris gallopavo]	sp|Q5M8M9|LRC52_MOUSE	sp|Q5M8M9|LRC52_MOUSE Leucine-rich repeat-containing protein 52 OS=Mus musculus GN=Lrrc52 PE=1 SV=1	9031.ENSGALP00000005441	leucine rich repeat containing 52	_	KOG0619	_	PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000005451|m.7117:103-160;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000005451|m.7117:128-185
ENSGALG00000003470	0.453741169	1.525738732	-1.727541085	1.02E-05	2.87E-05	down	yes	0.514059406	0.51151909	0.335645011	1.450218856	1.350550093	1.776447248	22	2825849	2861391	-	ZMAT4	protein_coding	GO:0072332|intrinsic apoptotic signaling pathway by p53 class mediator	GO:0005634|nucleus	GO:0002039|p53 binding; GO:0003677|DNA binding; GO:0003723|RNA binding; GO:0008270|zinc ion binding	--	--	1435	XP_015152892.1	XP_015152892.1 zinc finger matrin-type protein 4 [Gallus gallus]	sp|Q9H898|ZMAT4_HUMAN	sp|Q9H898|ZMAT4_HUMAN Zinc finger matrin-type protein 4 OS=Homo sapiens GN=ZMAT4 PE=1 SV=1	9031.ENSGALP00000005486	"zinc finger, matrin type 4"	_	_	NOG68898	PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000005496|m.4786:15-38;PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000005496|m.4786:76-99;PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000005496|m.4786:145-168;PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000005496|m.4786:197-221;PF12171.5|zf-C2H2_jaz|Zinc-finger double-stranded RNA-binding|ENSGALT00000005496|m.4786:145-169;PF12171.5|zf-C2H2_jaz|Zinc-finger double-stranded RNA-binding|ENSGALT00000005496|m.4786:197-222
ENSGALG00000003472	0.809347974	2.324601376	-1.510628041	5.21E-06	1.52E-05	down	yes	0.592034709	0.623990522	1.212018693	2.296519327	2.253670299	2.423614503	7	4153280	4189147	+	VWC2L	protein_coding	GO:0030514|negative regulation of BMP signaling pathway; GO:0045666|positive regulation of neuron differentiation	GO:0005615|extracellular space; GO:0030054|cell junction; GO:0032281|AMPA glutamate receptor complex; GO:0045202|synapse	--	--	--	1424	XP_426552.3	XP_426552.3 von Willebrand factor C domain-containing protein 2-like isoform X1 [Gallus gallus]	sp|Q505H4|VWC2L_MOUSE	sp|Q505H4|VWC2L_MOUSE von Willebrand factor C domain-containing protein 2-like OS=Mus musculus GN=Vwc2l PE=1 SV=1	9031.ENSGALP00000039153	von Willebrand factor C domain-containing protein 2-like	_	_	NOG83498	_
ENSGALG00000003520	7.015631849	14.38484024	-1.034851893	2.92E-16	2.13E-15	down	yes	6.586386138	6.89070845	7.569800959	15.03859992	13.95368857	14.16223222	18	6878337	6885109	-	POLG2	protein_coding	GO:0001701|in utero embryonic development; GO:0006260|DNA replication; GO:0006261|DNA-dependent DNA replication; GO:0006281|DNA repair; GO:0007005|mitochondrion organization; GO:0022904|respiratory electron transport chain; GO:0032042|mitochondrial DNA metabolic process; GO:0070150|mitochondrial glycyl-tRNA aminoacylation; GO:0070584|mitochondrion morphogenesis	GO:0000262|mitochondrial chromosome; GO:0005759|mitochondrial matrix; GO:0042645|mitochondrial nucleoid; GO:0070062|extracellular exosome	GO:0003677|DNA binding; GO:0003887|DNA-directed DNA polymerase activity; GO:0004820|glycine-tRNA ligase activity; GO:0042802|identical protein binding	ko:K02333|POLG2	ko01100|Metabolic pathways	1368	XP_415670.2	"XP_415670.2 DNA polymerase subunit gamma-2, mitochondrial [Gallus gallus]"	sp|Q9UHN1|DPOG2_HUMAN	"sp|Q9UHN1|DPOG2_HUMAN DNA polymerase subunit gamma-2, mitochondrial OS=Homo sapiens GN=POLG2 PE=1 SV=1"	9031.ENSGALP00000005560	"polymerase (DNA directed), gamma 2, accessory subunit"	COG0423	KOG2298	_	PF03129.17|HGTP_anticodon|Anticodon binding domain|ENSGALT00000005570|m.12825:361-447
ENSGALG00000003527	3.389846731	12.48130047	-1.87738207	9.14E-70	5.90E-68	down	yes	3.285180434	3.148930905	3.735428855	12.29084004	12.68854762	12.46451376	28	4148246	4156109	-	ARRDC2	protein_coding	--	GO:0005886|plasma membrane; GO:0031410|cytoplasmic vesicle	--	--	--	2987	XP_001233360.1	XP_001233360.1 arrestin domain-containing protein 2 isoform X2 [Gallus gallus]	sp|Q8TBH0|ARRD2_HUMAN	sp|Q8TBH0|ARRD2_HUMAN Arrestin domain-containing protein 2 OS=Homo sapiens GN=ARRDC2 PE=1 SV=2	9031.ENSGALP00000005571	arrestin domain containing 2	_	KOG3780	_	"PF00339.26|Arrestin_N|Arrestin (or S-antigen), N-terminal domain|ENSGALT00000103677|m.10410:18-155;PF02752.19|Arrestin_C|Arrestin (or S-antigen), C-terminal domain|ENSGALT00000103677|m.10410:178-303;PF03643.12|Vps26|Vacuolar protein sorting-associated protein 26|ENSGALT00000103677|m.10410:23-149"
ENSGALG00000003536	41.86904474	13.46953634	1.635457663	6.80E-137	2.22E-134	up	yes	41.79535501	41.39177157	42.42000764	13.28781575	13.80297996	13.31781331	27	7517127	7520296	-	KLHL11	protein_coding	GO:0006511|ubiquitin-dependent protein catabolic process; GO:0030162|regulation of proteolysis; GO:0043161|proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0043687|post-translational protein modification	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0019005|SCF ubiquitin ligase complex	GO:0031625|ubiquitin protein ligase binding	ko:K10449|KLHL11	--	3095	XP_003642870.1	XP_003642870.1 kelch-like protein 11 [Gallus gallus]	sp|Q9NVR0|KLH11_HUMAN	sp|Q9NVR0|KLH11_HUMAN Kelch-like protein 11 OS=Homo sapiens GN=KLHL11 PE=1 SV=1	59729.ENSTGUP00000002511	Kelch-like protein 11 Precursor [Taeniopygia guttata]	_	KOG1072	_	PF07707.12|BACK|BTB And C-terminal Kelch|ENSGALT00000005592|m.9346:189-290;PF00651.28|BTB|BTB/POZ domain|ENSGALT00000005592|m.9346:66-183;PF01344.22|Kelch_1|Kelch motif|ENSGALT00000005592|m.9346:429-470
ENSGALG00000003540	2.740128404	7.531274425	-1.45530937	2.44E-37	5.50E-36	down	yes	2.635971644	2.691228199	2.89318537	7.463023342	7.762829322	7.367970611	18	6895937	6909697	+	CEP95	protein_coding	--	GO:0000922|spindle pole; GO:0005737|cytoplasm; GO:0005813|centrosome	--	ko:K16544|CEP95	--	3718	XP_415671.3	XP_415671.3 centrosomal protein of 95 kDa isoform X1 [Gallus gallus]	sp|Q5XI03|CEP95_RAT	sp|Q5XI03|CEP95_RAT Centrosomal protein of 95 kDa OS=Rattus norvegicus GN=Cep95 PE=2 SV=1	9031.ENSGALP00000005592	coiled-coil domain containing 45	_	_	NOG80353	_
ENSGALG00000003550	0.044628606	0.313182284	-2.564619606	0.000110811	0.000270083	down	yes	0	0.021612952	0.112272865	0.304917811	0.343918561	0.29071048	20	3697349	3734407	-	ARHGAP40	protein_coding	GO:0007165|signal transduction; GO:0051056|regulation of small GTPase mediated signal transduction	GO:0005829|cytosol	GO:0005096|GTPase activator activity	ko:K20639|ARHGAP18_28_40	--	3467	XP_015151840.1	XP_015151840.1 rho GTPase-activating protein 40 isoform X3 [Gallus gallus]	sp|Q5TG30|RHG40_HUMAN	sp|Q5TG30|RHG40_HUMAN Rho GTPase-activating protein 40 OS=Homo sapiens GN=ARHGAP40 PE=3 SV=3	9031.ENSGALP00000005606	chromosome 20 open reading frame 95	_	KOG2200	_	PF00620.24|RhoGAP|RhoGAP domain|ENSGALT00000106950|m.2947:533-680
ENSGALG00000003553	0.369577708	1.140310915	-1.599556686	1.66E-13	9.87E-13	down	yes	0.330400977	0.530643477	0.247688669	1.090899842	1.217534703	1.112498202	7	4266278	4345086	-	ABCA12	protein_coding	GO:0006869|lipid transport; GO:0010875|positive regulation of cholesterol efflux; GO:0019725|cellular homeostasis; GO:0031424|keratinization; GO:0032940|secretion by cell; GO:0033700|phospholipid efflux; GO:0035627|ceramide transport; GO:0043129|surfactant homeostasis; GO:0045055|regulated exocytosis; GO:0048286|lung alveolus development; GO:0055085|transmembrane transport; GO:0055088|lipid homeostasis; GO:0061436|establishment of skin barrier; GO:0072659|protein localization to plasma membrane; GO:2000010|positive regulation of protein localization to cell surface	GO:0005737|cytoplasm; GO:0005743|mitochondrial inner membrane; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0043231|intracellular membrane-bounded organelle; GO:0097209|epidermal lamellar body	GO:0005102|signaling receptor binding; GO:0005319|lipid transporter activity; GO:0005524|ATP binding; GO:0034040|ATPase-coupled lipid transmembrane transporter activity; GO:0034191|apolipoprotein A-I receptor binding; GO:0042626|ATPase-coupled transmembrane transporter activity	ko:K05646|ABCA12	ko02010|ABC transporters	10047	XP_015144790.1	XP_015144790.1 ATP-binding cassette sub-family A member 12 isoform X3 [Gallus gallus]	sp|Q86UK0|ABCAC_HUMAN	sp|Q86UK0|ABCAC_HUMAN ATP-binding cassette sub-family A member 12 OS=Homo sapiens GN=ABCA12 PE=1 SV=3	9031.ENSGALP00000005610	"ATP-binding cassette, sub-family A (ABC1), member 12"	COG1131	KOG0059	_	"PF00005.24|ABC_tran|ABC transporter|ENSGALT00000005620|m.5664:2110-2255;PF00005.24|ABC_tran|ABC transporter|ENSGALT00000005620|m.5664:3021-3166;PF12698.4|ABC2_membrane_3|ABC-2 family transporter protein|ENSGALT00000005620|m.5664:1762-2020;PF12698.4|ABC2_membrane_3|ABC-2 family transporter protein|ENSGALT00000005620|m.5664:2639-2944;PF13304.3|AAA_21|AAA domain, putative AbiEii toxin, Type IV TA system|ENSGALT00000005620|m.5664:2226-2285;PF13304.3|AAA_21|AAA domain, putative AbiEii toxin, Type IV TA system|ENSGALT00000005620|m.5664:3135-3199"
ENSGALG00000003572	6.480664964	15.81591026	-1.285850288	5.53E-45	1.70E-43	down	yes	5.830135313	6.604402129	7.007457451	14.27314157	17.63289689	15.54169233	28	4172075	4211793	-	ENSGALG00000003572	protein_coding	GO:0007179|transforming growth factor beta receptor signaling pathway; GO:0007264|small GTPase mediated signal transduction; GO:0008360|regulation of cell shape; GO:0030036|actin cytoskeleton organization; GO:0035023|regulation of Rho protein signal transduction; GO:0043065|positive regulation of apoptotic process; GO:0051056|regulation of small GTPase mediated signal transduction	GO:0005829|cytosol; GO:0005856|cytoskeleton; GO:0005886|plasma membrane; GO:0016324|apical plasma membrane; GO:0030054|cell junction; GO:0045177|apical part of cell; GO:0070062|extracellular exosome	GO:0005085|guanyl-nucleotide exchange factor activity; GO:0005089|Rho guanyl-nucleotide exchange factor activity	ko:K21066|ARHGEF18	ko04530|Tight junction	6950	XP_418249.4	XP_418249.4 rho guanine nucleotide exchange factor 18 isoform X1 [Gallus gallus]	sp|Q6ZSZ5|ARHGI_HUMAN	sp|Q6ZSZ5|ARHGI_HUMAN Rho guanine nucleotide exchange factor 18 OS=Homo sapiens GN=ARHGEF18 PE=1 SV=3	9031.ENSGALP00000005645	rho/rac guanine nucleotide exchange factor (GEF) 18	_	KOG3520	_	PF00621.17|RhoGEF|RhoGEF domain|ENSGALT00000101887|m.10419:651-842;PF00130.19|C1_1|Phorbol esters/diacylglycerol binding domain (C1 domain)|ENSGALT00000101887|m.10419:447-492;PF00169.26|PH|PH domain|ENSGALT00000101887|m.10419:896-985
ENSGALG00000003602	1.813246757	5.196647547	-1.513844922	4.71E-27	6.54E-26	down	yes	1.741854185	1.935648643	1.762237442	4.622198065	5.634961883	5.332782692	11	4878175	4936909	+	RPGRIP1L	protein_coding	GO:0001701|in utero embryonic development; GO:0001736|establishment of planar polarity; GO:0001822|kidney development; GO:0001889|liver development; GO:0007163|establishment or maintenance of cell polarity; GO:0007368|determination of left/right symmetry; GO:0007420|brain development; GO:0008589|regulation of smoothened signaling pathway; GO:0021532|neural tube patterning; GO:0021537|telencephalon development; GO:0021549|cerebellum development; GO:0021670|lateral ventricle development; GO:0021772|olfactory bulb development; GO:0022038|corpus callosum development; GO:0035108|limb morphogenesis; GO:0035115|embryonic forelimb morphogenesis; GO:0035116|embryonic hindlimb morphogenesis; GO:0043010|camera-type eye development; GO:0043584|nose development; GO:0045744|negative regulation of G protein-coupled receptor signaling pathway; GO:0060039|pericardium development; GO:0060271|cilium assembly; GO:0060322|head development; GO:0090102|cochlea development; GO:1905515|non-motile cilium assembly	GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005813|centrosome; GO:0005829|cytosol; GO:0005879|axonemal microtubule; GO:0005886|plasma membrane; GO:0005911|cell-cell junction; GO:0005923|bicellular tight junction; GO:0005929|cilium; GO:0005930|axoneme; GO:0032391|photoreceptor connecting cilium; GO:0035253|ciliary rootlet; GO:0035869|ciliary transition zone; GO:0036064|ciliary basal body	GO:0031870|thromboxane A2 receptor binding	ko:K16550|RPGRIP1L	--	3829	XP_015147859.1	XP_015147859.1 protein fantom isoform X1 [Gallus gallus]	sp|Q8CG73|FTM_MOUSE	sp|Q8CG73|FTM_MOUSE Protein fantom OS=Mus musculus GN=Rpgrip1l PE=1 SV=2	9031.ENSGALP00000038922	RPGRIP1-like	_	_	NOG117461	PF11618.5|C2-C2_1|First C2 domain of RPGR-interacting protein 1|ENSGALT00000098565|m.6471:600-739;PF00168.27|C2|C2 domain|ENSGALT00000098565|m.6471:789-896
ENSGALG00000003660	5.585289082	1.781716442	1.642870337	1.70E-11	8.57E-11	up	yes	5.421447093	4.303522917	7.030897236	2.123534754	1.47078916	1.750825412	5	3167825	3169000	-	FANCF	protein_coding	GO:0001541|ovarian follicle development; GO:0007283|spermatogenesis; GO:0036297|interstrand cross-link repair	GO:0005654|nucleoplasm; GO:0043240|Fanconi anaemia nuclear complex	GO:0061630|ubiquitin protein ligase activity	ko:K10893|FANCF	ko03460|Fanconi anemia pathway	1176	XP_004941387.1	XP_004941387.1 Fanconi anemia group F protein [Gallus gallus]	sp|Q9NPI8|FANCF_HUMAN	sp|Q9NPI8|FANCF_HUMAN Fanconi anemia group F protein OS=Homo sapiens GN=FANCF PE=1 SV=1	9031.ENSGALP00000005790	"Fanconi anemia, complementation group F"	_	_	NOG41771	PF11107.5|FANCF|Fanconi anemia group F protein (FANCF)|ENSGALT00000005800|m.2284:42-378
ENSGALG00000003677	1.238587707	0.546923577	1.164745891	0.000234218	0.000543197	up	yes	1.513490454	0.967017764	1.235254902	0.683156031	0.410454818	0.547159883	17	6746034	6781803	+	NTNG2	protein_coding	GO:0006501|C-terminal protein lipidation; GO:0007409|axonogenesis	GO:0005576|extracellular region; GO:0005886|plasma membrane; GO:0030424|axon; GO:0046658|anchored component of plasma membrane	--	ko:K16359|NTNG2	ko04360|Axon guidance; ko04514|Cell adhesion molecules (CAMs)	2437	XP_015135244.1	XP_015135244.1 netrin-G2 isoform X5 [Gallus gallus]	sp|Q96CW9|NTNG2_HUMAN	sp|Q96CW9|NTNG2_HUMAN Netrin-G2 OS=Homo sapiens GN=NTNG2 PE=1 SV=2	_	_	_	_	_	PF00055.14|Laminin_N|Laminin N-terminal (Domain VI)|ENSGALT00000005827|m.12152:39-285;PF00053.21|Laminin_EGF|Laminin EGF domain|ENSGALT00000005827|m.12152:287-328;PF00053.21|Laminin_EGF|Laminin EGF domain|ENSGALT00000005827|m.12152:354-407;PF00053.21|Laminin_EGF|Laminin EGF domain|ENSGALT00000005827|m.12152:410-457
ENSGALG00000003682	13.19992495	5.637811708	1.225858374	2.73E-24	3.26E-23	up	yes	14.05985011	12.67558617	12.86433858	5.238410795	6.373081734	5.301942595	15	5492846	5498570	-	ARL6IP4	protein_coding	GO:0006397|mRNA processing; GO:0008380|RNA splicing	GO:0005634|nucleus; GO:0005730|nucleolus; GO:0016607|nuclear speck	--	--	--	1621	XP_015131095.1	XP_015131095.1 ADP-ribosylation factor-like protein 6-interacting protein 4 [Gallus gallus]	sp|Q5F4A9|AR6P4_CHICK	sp|Q5F4A9|AR6P4_CHICK ADP-ribosylation factor-like protein 6-interacting protein 4 OS=Gallus gallus GN=ARL6IP4 PE=2 SV=1	9031.ENSGALP00000038636	ADP-ribosylation factor-like protein 6-interacting protein 4 (ARL-6-interacting protein 4)(Aip-4)	_	_	NOG83556	PF10500.6|SR-25|Nuclear RNA-splicing-associated protein|ENSGALT00000005833|m.10493:6-229
ENSGALG00000003689	3.163562708	8.365962843	-1.400151693	5.68E-13	3.23E-12	down	yes	3.763649222	2.460029078	3.267009824	8.055165423	6.554057382	10.48866573	6	10302749	10312180	-	PAPSS2	protein_coding	GO:0000103|sulfate assimilation; GO:0001501|skeletal system development; GO:0007596|blood coagulation; GO:0050428|3'-phosphoadenosine 5'-phosphosulfate biosynthetic process; GO:0060348|bone development	GO:0005829|cytosol	GO:0004020|adenylylsulfate kinase activity; GO:0004781|sulfate adenylyltransferase (ATP) activity; GO:0005524|ATP binding; GO:0016779|nucleotidyltransferase activity	ko:K13811|PAPSS	ko00230|Purine metabolism; ko00261|Monobactam biosynthesis; ko00450|Selenocompound metabolism; ko00920|Sulfur metabolism; ko01100|Metabolic pathways; ko01120|Microbial metabolism in diverse environments; ko01130|Biosynthesis of antibiotics	1806	XP_015134189.1	XP_015134189.1 bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 isoform X2 [Gallus gallus]	sp|O95340|PAPS2_HUMAN	sp|O95340|PAPS2_HUMAN Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 OS=Homo sapiens GN=PAPSS2 PE=1 SV=2	9031.ENSGALP00000005834	3'-phosphoadenosine 5'-phosphosulfate synthase 2	COG0529;COG2046	KOG4238	_	PF01583.17|APS_kinase|Adenylylsulphate kinase|ENSGALT00000071572|m.4504:27-181;PF01747.14|ATP-sulfurylase|ATP-sulfurylase|ENSGALT00000071572|m.4504:370-592;PF14306.3|PUA_2|PUA-like domain|ENSGALT00000071572|m.4504:209-361
ENSGALG00000003691	15.43715322	4.6474249	1.729736575	2.58E-116	5.29E-114	up	yes	15.15595568	15.14402229	16.01148169	4.659306103	4.552105391	4.730863205	13	11336604	11375924	+	RNF145	protein_coding	GO:0000209|protein polyubiquitination; GO:0006511|ubiquitin-dependent protein catabolic process; GO:0043161|proteasome-mediated ubiquitin-dependent protein catabolic process	GO:0016021|integral component of membrane	GO:0008270|zinc ion binding; GO:0061630|ubiquitin protein ligase activity	--	--	4230	XP_001233173.1	XP_001233173.1 RING finger protein 145 isoform X1 [Gallus gallus]	sp|Q5SWK7|RN145_MOUSE	sp|Q5SWK7|RN145_MOUSE RING finger protein 145 OS=Mus musculus GN=Rnf145 PE=2 SV=1	9031.ENSGALP00000005837	Putative uncharacterized protein 	_	KOG0802	_	PF13705.3|TRC8_N|TRC8 N-terminal domain|ENSGALT00000084508|m.8765:90-345
ENSGALG00000003709	2.187657967	5.665928305	-1.368889497	7.95E-18	6.46E-17	down	yes	2.408438469	2.451890297	1.702645135	5.468166002	6.229125958	5.300492955	22	3021586	3034748	-	PLAT	protein_coding	GO:0001666|response to hypoxia; GO:0006464|cellular protein modification process; GO:0006508|proteolysis; GO:0007596|blood coagulation; GO:0014909|smooth muscle cell migration; GO:0031639|plasminogen activation; GO:0042730|fibrinolysis; GO:0045861|negative regulation of proteolysis; GO:0048008|platelet-derived growth factor receptor signaling pathway	GO:0005576|extracellular region; GO:0005737|cytoplasm; GO:0009986|cell surface; GO:0030141|secretory granule; GO:0045177|apical part of cell; GO:0070062|extracellular exosome	GO:0004252|serine-type endopeptidase activity; GO:0005102|signaling receptor binding; GO:0051219|phosphoprotein binding	ko:K01343|PLAT	ko04371|Apelin signaling pathway; ko04610|Complement and coagulation cascades; ko05202|Transcriptional misregulation in cancer; ko05418|Fluid shear stress and atherosclerosis	2886	XP_004947670.1	XP_004947670.1 tissue-type plasminogen activator isoform X1 [Gallus gallus]	sp|P00750|TPA_HUMAN	sp|P00750|TPA_HUMAN Tissue-type plasminogen activator OS=Homo sapiens GN=PLAT PE=1 SV=1	9031.ENSGALP00000005876	"plasminogen activator, tissue"	COG5640	KOG1217;KOG3627	_	PF00089.23|Trypsin|Trypsin|ENSGALT00000094332|m.4813:316-552;PF00051.15|Kringle|Kringle domain|ENSGALT00000094332|m.4813:128-209;PF00051.15|Kringle|Kringle domain|ENSGALT00000094332|m.4813:217-298
ENSGALG00000003727	9.663960106	20.22189091	-1.06445267	1.55E-29	2.35E-28	down	yes	10.17846184	9.923669844	8.889748631	19.72889324	21.36835344	19.56842604	28	4303372	4312690	+	HAUS8	protein_coding	GO:0000086|G2/M transition of mitotic cell cycle; GO:0007098|centrosome cycle; GO:0010389|regulation of G2/M transition of mitotic cell cycle; GO:0051225|spindle assembly; GO:0051301|cell division; GO:0097711|ciliary basal body-plasma membrane docking	GO:0000922|spindle pole; GO:0005813|centrosome; GO:0005829|cytosol; GO:0005874|microtubule; GO:0070652|HAUS complex	--	ko:K16591|HAUS8	--	2253	XP_010723367.1	XP_010723367.1 PREDICTED: HAUS augmin-like complex subunit 8 [Meleagris gallopavo]	sp|Q9BT25|HAUS8_HUMAN	sp|Q9BT25|HAUS8_HUMAN HAUS augmin-like complex subunit 8 OS=Homo sapiens GN=HAUS8 PE=1 SV=3	9031.ENSGALP00000005905	"HAUS augmin-like complex, subunit 8"	_	_	NOG47763	_
ENSGALG00000003734	30.92863242	15.45500437	1.000402185	1.87E-38	4.39E-37	up	yes	31.38940911	30.02179316	31.374695	16.36407769	14.05607485	15.94486058	21	4377697	4391855	+	SZRD1	protein_coding	--	--	--	--	--	2953	XP_012669158.1	XP_012669158.1 SUZ domain-containing protein 1-like [Otolemur garnettii]	sp|Q5ZK25|SZRD1_CHICK	sp|Q5ZK25|SZRD1_CHICK SUZ domain-containing protein 1 OS=Gallus gallus GN=SZRD1 PE=2 SV=1	9031.ENSGALP00000005915	UPF0485 protein C1orf144 homolog 	_	_	NOG26282	PF12752.4|SUZ|SUZ domain|ENSGALT00000005925|m.4116:65-116;PF12901.4|SUZ-C|SUZ-C motif|ENSGALT00000005925|m.4116:131-160
ENSGALG00000003759	1.215257848	3.639624664	-1.574662715	3.06E-15	2.08E-14	down	yes	0.807589417	1.268839847	1.569344279	3.527489907	3.53945865	3.851925436	10	5138735	5486292	+	RORA	protein_coding	"GO:0001525|angiogenesis; GO:0006355|regulation of transcription, DNA-templated; GO:0006367|transcription initiation from RNA polymerase II promoter; GO:0006805|xenobiotic metabolic process; GO:0006809|nitric oxide biosynthetic process; GO:0008589|regulation of smoothened signaling pathway; GO:0010575|positive regulation of vascular endothelial growth factor production; GO:0010906|regulation of glucose metabolic process; GO:0019218|regulation of steroid metabolic process; GO:0021702|cerebellar Purkinje cell differentiation; GO:0021930|cerebellar granule cell precursor proliferation; GO:0030522|intracellular receptor signaling pathway; GO:0032922|circadian regulation of gene expression; GO:0036315|cellular response to sterol; GO:0042632|cholesterol homeostasis; GO:0042692|muscle cell differentiation; GO:0042753|positive regulation of circadian rhythm; GO:0043030|regulation of macrophage activation; GO:0043124|negative regulation of I-kappaB kinase/NF-kappaB signaling; GO:0045599|negative regulation of fat cell differentiation; GO:0045893|positive regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0046068|cGMP metabolic process; GO:0050728|negative regulation of inflammatory response; GO:0060850|regulation of transcription involved in cell fate commitment; GO:0070328|triglyceride homeostasis; GO:0071347|cellular response to interleukin-1; GO:0071356|cellular response to tumor necrosis factor; GO:0071456|cellular response to hypoxia; GO:0072539|T-helper 17 cell differentiation"	GO:0005634|nucleus; GO:0005654|nucleoplasm	"GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding; GO:0001046|core promoter sequence-specific DNA binding; GO:0001222|transcription corepressor binding; GO:0001223|transcription coactivator binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity; GO:0003707|steroid hormone receptor activity; GO:0004879|nuclear receptor activity; GO:0008013|beta-catenin binding; GO:0008134|transcription factor binding; GO:0008142|oxysterol binding; GO:0008270|zinc ion binding; GO:0043565|sequence-specific DNA binding; GO:0098531|ligand-activated transcription factor activity"	"ko:K08532|NR1F1,RORA"	ko04659|Th17 cell differentiation; ko04710|Circadian rhythm; ko05321|Inflammatory bowel disease (IBD)	2979	XP_015134374.1	XP_015134374.1 nuclear receptor ROR-alpha isoform X3 [Gallus gallus]	sp|P35398|RORA_HUMAN	sp|P35398|RORA_HUMAN Nuclear receptor ROR-alpha OS=Homo sapiens GN=RORA PE=1 SV=2	13616.ENSMODP00000014431	RAR-related orphan receptor A	_	KOG4216	_	"PF00105.15|zf-C4|Zinc finger, C4 type (two domains)|ENSGALT00000005967|m.5360:17-85;PF00104.27|Hormone_recep|Ligand-binding domain of nuclear hormone receptor|ENSGALT00000005967|m.5360:258-437"
ENSGALG00000003767	11.14443005	24.49056063	-1.135197962	3.01E-26	4.00E-25	down	yes	9.948382054	12.635243	10.84966511	21.64979375	28.52547837	23.29640978	11	6241053	6411630	-	NKD1	protein_coding	"GO:0001754|eye photoreceptor cell differentiation; GO:0007525|somatic muscle development; GO:0016055|Wnt signaling pathway; GO:0045732|positive regulation of protein catabolic process; GO:0090090|negative regulation of canonical Wnt signaling pathway; GO:0090249|regulation of cell motility involved in somitogenic axis elongation; GO:1901231|positive regulation of non-canonical Wnt signaling pathway via JNK cascade; GO:1901233|negative regulation of convergent extension involved in axis elongation; GO:2000096|positive regulation of Wnt signaling pathway, planar cell polarity pathway"	GO:0005737|cytoplasm; GO:0005886|plasma membrane	GO:0005509|calcium ion binding; GO:0030165|PDZ domain binding	ko:K03213|NKD	ko04310|Wnt signaling pathway	3727	XP_414094.3	XP_414094.3 protein naked cuticle homolog 1 isoform X1 [Gallus gallus]	sp|Q969G9|NKD1_HUMAN	sp|Q969G9|NKD1_HUMAN Protein naked cuticle homolog 1 OS=Homo sapiens GN=NKD1 PE=1 SV=1	9031.ENSGALP00000005967	similar to Nkd	_	_	NOG47986	_
ENSGALG00000003770	23.38679823	9.467459782	1.303738781	4.97E-40	1.24E-38	up	yes	24.38269792	23.02657374	22.75112302	10.06936559	10.22061566	8.112398091	10	5524170	5556443	+	ANXA2	protein_coding	GO:0003417|growth plate cartilage development; GO:0010755|regulation of plasminogen activation; GO:0030282|bone mineralization; GO:0032332|positive regulation of chondrocyte differentiation; GO:0032907|transforming growth factor beta3 production; GO:0036366|transforming growth factor beta3 activation; GO:0051928|positive regulation of calcium ion transport; GO:0055074|calcium ion homeostasis; GO:0060956|endocardial cell differentiation	GO:0005604|basement membrane; GO:0005886|plasma membrane; GO:0031012|extracellular matrix; GO:0031982|vesicle; GO:0032991|protein-containing complex; GO:0034704|calcium channel complex	GO:0004859|phospholipase inhibitor activity; GO:0005262|calcium channel activity; GO:0005509|calcium ion binding; GO:0005544|calcium-dependent phospholipid binding; GO:0008092|cytoskeletal protein binding; GO:0046790|virion binding; GO:0099511|voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels	ko:K17092|ANXA2	--	2072	NP_990682.1	NP_990682.1 annexin A2 [Gallus gallus]	sp|P17785|ANXA2_CHICK	sp|P17785|ANXA2_CHICK Annexin A2 OS=Gallus gallus GN=ANXA2 PE=1 SV=2	_	_	_	_	_	PF00191.17|Annexin|Annexin|ENSGALT00000050124|m.5366:37-102;PF00191.17|Annexin|Annexin|ENSGALT00000050124|m.5366:109-174;PF00191.17|Annexin|Annexin|ENSGALT00000050124|m.5366:193-259;PF00191.17|Annexin|Annexin|ENSGALT00000050124|m.5366:269-334
ENSGALG00000003793	14.58205162	5.892316965	1.305829435	1.67E-17	1.33E-16	up	yes	13.31320695	15.15671647	15.27623144	6.19100182	5.109808769	6.376140307	10	5843239	5848304	+	GTF2A2	protein_coding	GO:0006366|transcription by RNA polymerase II; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0051091|positive regulation of DNA-binding transcription factor activity; GO:0051123|RNA polymerase II preinitiation complex assembly	GO:0005654|nucleoplasm; GO:0005669|transcription factor TFIID complex; GO:0005672|transcription factor TFIIA complex; GO:0030054|cell junction	GO:0001103|RNA polymerase II repressing transcription factor binding; GO:0003713|transcription coactivator activity; GO:0008134|transcription factor binding; GO:0017025|TBP-class protein binding; GO:0042803|protein homodimerization activity; GO:0046982|protein heterodimerization activity	"ko:K03123|TFIIA2,GTF2A2,TOA2"	ko03022|Basal transcription factors; ko05203|Viral carcinogenesis	858	BAE38203.1	BAE38203.1 unnamed protein product [Mus musculus]	sp|Q80ZM7|T2AG_MOUSE	sp|Q80ZM7|T2AG_MOUSE Transcription initiation factor IIA subunit 2 OS=Mus musculus GN=Gtf2a2 PE=1 SV=2	_	_	_	_	_	"PF02751.11|TFIIA_gamma_C|Transcription initiation factor IIA, gamma subunit|ENSGALT00000089760|m.5372:52-100;PF02268.13|TFIIA_gamma_N|Transcription initiation factor IIA, gamma subunit, helical domain|ENSGALT00000089760|m.5372:3-48"
ENSGALG00000003803	0.808502305	2.271242496	-1.478761429	1.14E-13	6.88E-13	down	yes	0.701768112	0.921878773	0.80186003	2.287729635	2.289760469	2.236237386	Z	12347586	12371157	-	DAB2	protein_coding	"GO:0001934|positive regulation of protein phosphorylation; GO:0006915|apoptotic process; GO:0007275|multicellular organism development; GO:0008283|cell population proliferation; GO:0010718|positive regulation of epithelial to mesenchymal transition; GO:0010862|positive regulation of pathway-restricted SMAD protein phosphorylation; GO:0015031|protein transport; GO:0016055|Wnt signaling pathway; GO:0030335|positive regulation of cell migration; GO:0030511|positive regulation of transforming growth factor beta receptor signaling pathway; GO:0032091|negative regulation of protein binding; GO:0032436|positive regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0035026|leading edge cell differentiation; GO:0043066|negative regulation of apoptotic process; GO:0045807|positive regulation of endocytosis; GO:0045892|negative regulation of transcription, DNA-templated; GO:0045893|positive regulation of transcription, DNA-templated; GO:0060391|positive regulation of SMAD protein signal transduction; GO:0060766|negative regulation of androgen receptor signaling pathway; GO:0061024|membrane organization; GO:0090090|negative regulation of canonical Wnt signaling pathway; GO:1903077|negative regulation of protein localization to plasma membrane; GO:2000096|positive regulation of Wnt signaling pathway, planar cell polarity pathway; GO:2000370|positive regulation of clathrin-dependent endocytosis; GO:2000643|positive regulation of early endosome to late endosome transport"	GO:0001650|fibrillar center; GO:0005730|nucleolus; GO:0005765|lysosomal membrane; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0005905|clathrin-coated pit; GO:0005925|focal adhesion; GO:0030136|clathrin-coated vesicle; GO:0030665|clathrin-coated vesicle membrane; GO:0043231|intracellular membrane-bounded organelle; GO:0070062|extracellular exosome	GO:0008022|protein C-terminus binding; GO:0035615|clathrin adaptor activity; GO:0038024|cargo receptor activity; GO:0046332|SMAD binding	ko:K12475|DAB2	ko04144|Endocytosis	3449	XP_015133023.1	XP_015133023.1 disabled homolog 2 isoform X1 [Gallus gallus]	sp|P98082|DAB2_HUMAN	sp|P98082|DAB2_HUMAN Disabled homolog 2 OS=Homo sapiens GN=DAB2 PE=1 SV=3	_	_	_	_	_	PF00640.20|PID|Phosphotyrosine interaction domain (PTB/PID)|ENSGALT00000097380|m.10698:54-176
ENSGALG00000003816	0.282223493	0.75308928	-1.384779695	0.000709636	0.001529255	down	yes	0.385074951	0.282337288	0.179258239	0.893212345	0.753017804	0.613037692	23	5644988	5652023	-	NT5C1A	protein_coding	GO:0006195|purine nucleotide catabolic process; GO:0009116|nucleoside metabolic process; GO:0009128|purine nucleoside monophosphate catabolic process; GO:0046085|adenosine metabolic process; GO:0046135|pyrimidine nucleoside catabolic process	GO:0005829|cytosol	GO:0000166|nucleotide binding; GO:0000287|magnesium ion binding; GO:0008253|5'-nucleotidase activity	ko:K01081|E3.1.3.5	ko00230|Purine metabolism; ko00240|Pyrimidine metabolism; ko00760|Nicotinate and nicotinamide metabolism; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites	2211	XP_024998879.1	XP_024998879.1 cytosolic 5'-nucleotidase 1A isoform X2 [Gallus gallus]	sp|Q9BXI3|5NT1A_HUMAN	sp|Q9BXI3|5NT1A_HUMAN Cytosolic 5'-nucleotidase 1A OS=Homo sapiens GN=NT5C1A PE=1 SV=1	9031.ENSGALP00000006041	"5'-nucleotidase, cytosolic IA"	_	_	NOG46880	PF06189.9|5-nucleotidase|5'-nucleotidase|ENSGALT00000107933|m.5833:142-413
ENSGALG00000003829	0.190530085	0.743200857	-1.909215944	0.000617955	0.001346331	down	yes	0.280644949	0.07716342	0.213781887	0.791730667	0.693712821	0.744159083	23	5653211	5655702	-	HPCAL4	protein_coding	GO:0007165|signal transduction	GO:0005622|intracellular	GO:0005246|calcium channel regulator activity; GO:0005509|calcium ion binding; GO:0008022|protein C-terminus binding; GO:0019904|protein domain specific binding	--	--	1502	XP_015739246.1	XP_015739246.1 PREDICTED: hippocalcin-like protein 4 isoform X1 [Coturnix japonica]	sp|Q8BGZ1|HPCL4_MOUSE	sp|Q8BGZ1|HPCL4_MOUSE Hippocalcin-like protein 4 OS=Mus musculus GN=Hpcal4 PE=1 SV=3	_	_	_	_	_	PF13499.3|EF-hand_7|EF-hand domain pair|ENSGALT00000006069|m.5835:138-215;PF00036.29|EF-hand_1|EF hand|ENSGALT00000006069|m.5835:106-130;PF00036.29|EF-hand_1|EF hand|ENSGALT00000006069|m.5835:141-166;PF00036.29|EF-hand_1|EF hand|ENSGALT00000006069|m.5835:191-217;PF13405.3|EF-hand_6|EF-hand domain|ENSGALT00000006069|m.5835:106-130;PF13202.3|EF-hand_5|EF hand|ENSGALT00000006069|m.5835:107-125;PF13202.3|EF-hand_5|EF hand|ENSGALT00000006069|m.5835:144-162;PF13202.3|EF-hand_5|EF hand|ENSGALT00000006069|m.5835:192-213;PF13833.3|EF-hand_8|EF-hand domain pair|ENSGALT00000006069|m.5835:81-126;PF13833.3|EF-hand_8|EF-hand domain pair|ENSGALT00000006069|m.5835:153-214
ENSGALG00000003851	6.878996399	13.83443078	-1.006940009	6.70E-15	4.44E-14	down	yes	7.973360573	6.377536252	6.286092372	15.46772228	13.25324765	12.78232242	23	5664869	5678872	-	TRIT1	protein_coding	GO:0006400|tRNA modification; GO:0070900|mitochondrial tRNA modification	GO:0005739|mitochondrion; GO:0005759|mitochondrial matrix	GO:0003676|nucleic acid binding; GO:0005524|ATP binding; GO:0008270|zinc ion binding; GO:0052381|tRNA dimethylallyltransferase activity	"ko:K00791|miaA,TRIT1"	ko00908|Zeatin biosynthesis; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites	1890	XP_004947943.2	XP_004947943.2 tRNA dimethylallyltransferase [Gallus gallus]	sp|Q9H3H1|MOD5_HUMAN	sp|Q9H3H1|MOD5_HUMAN tRNA dimethylallyltransferase OS=Homo sapiens GN=TRIT1 PE=1 SV=1	9031.ENSGALP00000006110	tRNA isopentenyltransferase 1	COG0324	KOG1384	_	PF01715.14|IPPT|IPP transferase|ENSGALT00000006120|m.5840:60-335;PF01745.13|IPT|Isopentenyl transferase|ENSGALT00000006120|m.5840:28-71;PF12171.5|zf-C2H2_jaz|Zinc-finger double-stranded RNA-binding|ENSGALT00000006120|m.5840:400-422
ENSGALG00000003863	1.896252098	0.777228697	1.275884208	4.66E-07	1.54E-06	up	yes	2.254368569	1.498820629	1.935567097	0.783300468	0.936929845	0.611455778	15	5714657	5727150	+	P2RX7	protein_coding	GO:0000187|activation of MAPK activity; GO:0000902|cell morphogenesis; GO:0001845|phagolysosome assembly; GO:0001916|positive regulation of T cell mediated cytotoxicity; GO:0001934|positive regulation of protein phosphorylation; GO:0006468|protein phosphorylation; GO:0006509|membrane protein ectodomain proteolysis; GO:0006649|phospholipid transfer to membrane; GO:0006812|cation transport; GO:0006816|calcium ion transport; GO:0006884|cell volume homeostasis; GO:0006900|vesicle budding from membrane; GO:0006954|inflammatory response; GO:0007005|mitochondrion organization; GO:0007009|plasma membrane organization; GO:0009612|response to mechanical stimulus; GO:0009617|response to bacterium; GO:0010033|response to organic substance; GO:0010043|response to zinc ion; GO:0010467|gene expression; GO:0010524|positive regulation of calcium ion transport into cytosol; GO:0010628|positive regulation of gene expression; GO:0012501|programmed cell death; GO:0014049|positive regulation of glutamate secretion; GO:0014054|positive regulation of gamma-aminobutyric acid secretion; GO:0014070|response to organic cyclic compound; GO:0016079|synaptic vesicle exocytosis; GO:0016485|protein processing; GO:0017121|plasma membrane phospholipid scrambling; GO:0019233|sensory perception of pain; GO:0019835|cytolysis; GO:0030163|protein catabolic process; GO:0030501|positive regulation of bone mineralization; GO:0031668|cellular response to extracellular stimulus; GO:0032060|bleb assembly; GO:0032308|positive regulation of prostaglandin secretion; GO:0032496|response to lipopolysaccharide; GO:0032731|positive regulation of interleukin-1 beta production; GO:0032755|positive regulation of interleukin-6 production; GO:0032963|collagen metabolic process; GO:0033198|response to ATP; GO:0034405|response to fluid shear stress; GO:0034767|positive regulation of ion transmembrane transport; GO:0035590|purinergic nucleotide receptor signaling pathway; GO:0042098|T cell proliferation; GO:0042493|response to drug; GO:0043029|T cell homeostasis; GO:0043065|positive regulation of apoptotic process; GO:0043085|positive regulation of catalytic activity; GO:0043132|NAD transport; GO:0043409|negative regulation of MAPK cascade; GO:0043410|positive regulation of MAPK cascade; GO:0045332|phospholipid translocation; GO:0045778|positive regulation of ossification; GO:0045779|negative regulation of bone resorption; GO:0045794|negative regulation of cell volume; GO:0045821|positive regulation of glycolytic process; GO:0046513|ceramide biosynthetic process; GO:0046931|pore complex assembly; GO:0048705|skeletal system morphogenesis; GO:0048873|homeostasis of number of cells within a tissue; GO:0050714|positive regulation of protein secretion; GO:0050715|positive regulation of cytokine secretion; GO:0050717|positive regulation of interleukin-1 alpha secretion; GO:0050718|positive regulation of interleukin-1 beta secretion; GO:0050830|defense response to Gram-positive bacterium; GO:0051209|release of sequestered calcium ion into cytosol; GO:0051259|protein complex oligomerization; GO:0051592|response to calcium ion; GO:0051602|response to electrical stimulus; GO:0051899|membrane depolarization; GO:0051901|positive regulation of mitochondrial depolarization; GO:0070230|positive regulation of lymphocyte apoptotic process; GO:0071359|cellular response to dsRNA; GO:0071407|cellular response to organic cyclic compound; GO:0072593|reactive oxygen species metabolic process; GO:0097191|extrinsic apoptotic signaling pathway; GO:1904172|positive regulation of bleb assembly	GO:0005639|integral component of nuclear inner membrane; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0005911|cell-cell junction; GO:0009897|external side of plasma membrane; GO:0016020|membrane; GO:0031594|neuromuscular junction; GO:0043025|neuronal cell body; GO:0045202|synapse; GO:0098793|presynapse; GO:0098794|postsynapse	GO:0001530|lipopolysaccharide binding; GO:0001614|purinergic nucleotide receptor activity; GO:0004931|extracellularly ATP-gated cation channel activity; GO:0005524|ATP binding; GO:0015267|channel activity; GO:0038023|signaling receptor activity	ko:K05220|P2RX7	ko04020|Calcium signaling pathway; ko04080|Neuroactive ligand-receptor interaction; ko04621|NOD-like receptor signaling pathway	2735	XP_001235163.3	XP_001235163.3 P2X purinoceptor 7 [Gallus gallus]	sp|Q9Z1M0|P2RX7_MOUSE	sp|Q9Z1M0|P2RX7_MOUSE P2X purinoceptor 7 OS=Mus musculus GN=P2rx7 PE=1 SV=2	_	_	_	_	_	PF00864.16|P2X_receptor|ATP P2X receptor|ENSGALT00000090460|m.10512:23-357
ENSGALG00000003876	0.083145536	0.319005173	-1.820551728	0.001399762	0.00288574	down	yes	0.089095518	0.065324911	0.09501618	0.26810494	0.324179954	0.364730624	13	12172827	12188986	+	TIMD4	protein_coding	--	GO:0016021|integral component of membrane	GO:0001786|phosphatidylserine binding	--	--	2439	CDG64120.1	CDG64120.1 T cell immunoglobulin and mucin 4 variant L1 [Gallus gallus]	sp|Q6U7R4|TIMD4_MOUSE	sp|Q6U7R4|TIMD4_MOUSE T-cell immunoglobulin and mucin domain-containing protein 4 OS=Mus musculus GN=Timd4 PE=1 SV=2	9031.ENSGALP00000006155	T-cell immunoglobulin and mucin domain containing 4 	_	_	NOG40586	PF07686.14|V-set|Immunoglobulin V-set domain|ENSGALT00000105829|m.8799:22-129;PF07686.14|V-set|Immunoglobulin V-set domain|ENSGALT00000105829|m.8799:208-315;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000105829|m.8799:26-118
ENSGALG00000003933	73.0637673	36.48336554	1.00171938	1.03E-39	2.54E-38	up	yes	75.74224001	71.28048989	72.168572	35.68694473	33.21498	40.54817188	8	6368170	6376220	-	QSOX1	protein_coding	GO:0016242|negative regulation of macroautophagy; GO:0045454|cell redox homeostasis	GO:0005615|extracellular space; GO:0030173|integral component of Golgi membrane; GO:0045171|intercellular bridge; GO:0070062|extracellular exosome	GO:0003756|protein disulfide isomerase activity; GO:0016971|flavin-linked sulfhydryl oxidase activity	ko:K10758|QSOX	--	2743	NP_989456.1	NP_989456.1 sulfhydryl oxidase 1 precursor [Gallus gallus]	sp|Q8JGM4|QSOX1_CHICK	sp|Q8JGM4|QSOX1_CHICK Sulfhydryl oxidase 1 OS=Gallus gallus GN=QSOX1 PE=1 SV=1	59729.ENSTGUP00000017654	Sulfhydryl oxidase 1 Precursor (hQSOX)(EC 1.8.3.2)(Quiescin Q6) [Taeniopygia guttata]	_	KOG1731	_	PF04777.10|Evr1_Alr|Erv1 / Alr family|ENSGALT00000099189|m.7181:439-534;PF00085.17|Thioredoxin|Thioredoxin|ENSGALT00000099189|m.7181:88-160
ENSGALG00000003948	79.55059947	354.194938	-2.154458273	3.76E-177	2.06E-174	down	yes	81.25648972	77.67767612	79.71763258	374.8392763	307.5894645	380.1560733	12	3345428	3352328	+	ALAS2	protein_coding	GO:0006782|protoporphyrinogen IX biosynthetic process; GO:0006783|heme biosynthetic process	GO:0005759|mitochondrial matrix; GO:0005829|cytosol	GO:0003870|5-aminolevulinate synthase activity; GO:0030170|pyridoxal phosphate binding	"ko:K00643|E2.3.1.37,ALAS"	"ko00260|Glycine, serine and threonine metabolism; ko00860|Porphyrin and chlorophyll metabolism; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites"	2160	NP_001018012.1	"NP_001018012.1 5-aminolevulinate synthase, nonspecific, mitochondrial precursor [Gallus gallus]"	sp|P07997|HEM1_CHICK	"sp|P07997|HEM1_CHICK 5-aminolevulinate synthase, nonspecific, mitochondrial OS=Gallus gallus GN=ALAS1 PE=2 SV=2"	_	_	_	_	_	PF00155.18|Aminotran_1_2|Aminotransferase class I and II|ENSGALT00000061450|m.7332:240-585;PF09029.7|Preseq_ALAS|5-aminolevulinate synthase presequence|ENSGALT00000061450|m.7332:2-131;PF01053.17|Cys_Met_Meta_PP|Cys/Met metabolism PLP-dependent enzyme|ENSGALT00000061450|m.7332:287-412;PF00266.16|Aminotran_5|Aminotransferase class-V|ENSGALT00000061450|m.7332:354-412
ENSGALG00000003955	15.33987698	37.94162568	-1.305934592	4.12E-94	4.41E-92	down	yes	16.13891816	15.14067405	14.74003874	36.01973125	39.24057135	38.56457443	8	6384431	6436044	-	CEP350	protein_coding	GO:0034453|microtubule anchoring	GO:0005634|nucleus; GO:0005813|centrosome; GO:0005814|centriole; GO:0005819|spindle; GO:0016020|membrane; GO:0042995|cell projection	GO:0008017|microtubule binding	ko:K16768|CEP350	--	9566	XP_015145979.1	XP_015145979.1 centrosome-associated protein 350 isoform X1 [Gallus gallus]	sp|Q5VT06|CE350_HUMAN	sp|Q5VT06|CE350_HUMAN Centrosome-associated protein 350 OS=Homo sapiens GN=CEP350 PE=1 SV=1	9031.ENSGALP00000006296	centrosomal protein 350kDa	COG5244	KOG4568	_	PF01302.22|CAP_GLY|CAP-Gly domain|ENSGALT00000100477|m.7185:2543-2607
ENSGALG00000003979	0.851858871	1.894126692	-1.143605919	5.03E-07	1.66E-06	down	yes	1.044767134	0.714955892	0.795853588	1.755343114	1.976480904	1.950556057	19	5957276	5967069	+	ENSGALG00000003979	protein_coding	GO:0007368|determination of left/right symmetry; GO:0007507|heart development; GO:0009887|animal organ morphogenesis; GO:0035330|regulation of hippo signaling	GO:0005737|cytoplasm; GO:0005856|cytoskeleton; GO:0005929|cilium; GO:0097543|ciliary inversin compartment; GO:0097546|ciliary base	GO:0004674|protein serine/threonine kinase activity; GO:0005524|ATP binding; GO:0046872|metal ion binding	ko:K20877|NEK8	--	3026	XP_004946640.1	XP_004946640.1 serine/threonine-protein kinase Nek8 isoform X1 [Gallus gallus]	sp|Q86SG6|NEK8_HUMAN	sp|Q86SG6|NEK8_HUMAN Serine/threonine-protein kinase Nek8 OS=Homo sapiens GN=NEK8 PE=1 SV=1	9031.ENSGALP00000006330	NIMA (never in mitosis gene a)- related kinase 8	COG0515	KOG0589	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000094370|m.13908:22-260;PF00415.15|RCC1|Regulator of chromosome condensation (RCC1) repeat|ENSGALT00000094370|m.13908:425-469;PF00415.15|RCC1|Regulator of chromosome condensation (RCC1) repeat|ENSGALT00000094370|m.13908:474-521;PF00415.15|RCC1|Regulator of chromosome condensation (RCC1) repeat|ENSGALT00000094370|m.13908:590-639;PF00415.15|RCC1|Regulator of chromosome condensation (RCC1) repeat|ENSGALT00000094370|m.13908:642-690;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000094370|m.13908:29-259;PF13540.3|RCC1_2|Regulator of chromosome condensation (RCC1) repeat|ENSGALT00000094370|m.13908:457-484
ENSGALG00000004040	22.59391668	11.01557337	1.035719094	2.35E-44	7.07E-43	up	yes	22.68994268	23.41683242	21.67497495	10.52622969	11.75203834	10.76845208	13	12969660	12979696	-	MFAP3	protein_coding	--	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	--	--	--	4598	XP_015149267.1	XP_015149267.1 microfibril-associated glycoprotein 3 isoform X1 [Gallus gallus]	sp|Q5R9E4|MFAP3_PONAB	sp|Q5R9E4|MFAP3_PONAB Microfibril-associated glycoprotein 3 OS=Pongo abelii GN=MFAP3 PE=2 SV=1	9031.ENSGALP00000006422	microfibrillar-associated protein 3 	_	_	NOG47734	PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000006432|m.8832:54-136;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000006432|m.8832:53-133
ENSGALG00000004068	20.76158954	45.56549328	-1.133646649	9.07E-49	3.15E-47	down	yes	19.27137061	22.44919218	20.56420584	43.10192177	47.60629925	45.98825883	13	12979764	12989584	+	FAM114A2	protein_coding	--	--	--	--	--	2633	XP_414580.1	XP_414580.1 protein FAM114A2 [Gallus gallus]	sp|Q2T9N1|F1142_BOVIN	sp|Q2T9N1|F1142_BOVIN Protein FAM114A2 OS=Bos taurus GN=FAM114A1 PE=2 SV=1	9031.ENSGALP00000006461	chromosome 5 open reading frame 3	_	_	NOG131151	PF05334.10|DUF719|Protein of unknown function (DUF719)|ENSGALT00000006471|m.8833:75-250
ENSGALG00000004070	3.693015483	9.864335835	-1.414983132	2.43E-31	4.16E-30	down	yes	4.1239263	3.52373424	3.43138591	9.360940077	11.05314648	9.178920945	14	2927831	2938908	-	MICALL2	protein_coding	GO:0030041|actin filament polymerization; GO:0031175|neuron projection development; GO:0031532|actin cytoskeleton reorganization; GO:0032456|endocytic recycling; GO:0034446|substrate adhesion-dependent cell spreading; GO:0070830|bicellular tight junction assembly; GO:1903955|positive regulation of protein targeting to mitochondrion	GO:0001725|stress fiber; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0005911|cell-cell junction; GO:0005923|bicellular tight junction; GO:0043005|neuron projection; GO:0055037|recycling endosome	GO:0017137|Rab GTPase binding; GO:0031005|filamin binding; GO:0042805|actinin binding; GO:0046872|metal ion binding; GO:0051015|actin filament binding	"ko:K21068|MICALL2,JRAB"	ko04530|Tight junction	3322	XP_414767.4	XP_414767.4 MICAL-like protein 2 isoform X2 [Gallus gallus]	sp|Q8IY33|MILK2_HUMAN	sp|Q8IY33|MILK2_HUMAN MICAL-like protein 2 OS=Homo sapiens GN=MICALL2 PE=1 SV=1	9031.ENSGALP00000006463	MICAL-like 2	COG5069	KOG1700	_	PF12130.5|DUF3585|Protein of unknown function (DUF3585)|ENSGALT00000006473|m.9268:462-593;PF00412.19|LIM|LIM domain|ENSGALT00000006473|m.9268:18-70
ENSGALG00000004071	2.960737166	25.80981167	-3.119585603	2.32E-158	1.04E-155	down	yes	2.21455302	3.177436801	3.490221676	25.16952908	26.31318081	25.94672512	11	7656093	7683363	+	NETO2	protein_coding	GO:2000312|regulation of kainate selective glutamate receptor activity	GO:0014069|postsynaptic density; GO:0016021|integral component of membrane	GO:0035255|ionotropic glutamate receptor binding	--	--	2008	XP_004944245.2	XP_004944245.2 neuropilin and tolloid-like protein 2 isoform X1 [Gallus gallus]	sp|Q8NC67|NETO2_HUMAN	sp|Q8NC67|NETO2_HUMAN Neuropilin and tolloid-like protein 2 OS=Homo sapiens GN=NETO2 PE=1 SV=1	9031.ENSGALP00000006464	neuropilin (NRP) and tolloid (TLL)-like 2	_	KOG4586	_	PF00431.17|CUB|CUB domain|ENSGALT00000091133|m.6556:45-156;PF00431.17|CUB|CUB domain|ENSGALT00000091133|m.6556:203-286;PF00057.15|Ldl_recept_a|Low-density lipoprotein receptor domain class A|ENSGALT00000091133|m.6556:296-331
ENSGALG00000004078	4.258241169	9.537278674	-1.161447875	1.28E-14	8.27E-14	down	yes	4.266484948	4.242608324	4.265630236	7.953941578	11.21052558	9.447368864	13	13001201	13010129	+	ENSGALG00000004078	protein_coding	GO:0000209|protein polyubiquitination; GO:0032436|positive regulation of proteasomal ubiquitin-dependent protein catabolic process	GO:0005622|intracellular	GO:0004842|ubiquitin-protein transferase activity; GO:0031624|ubiquitin conjugating enzyme binding; GO:0046872|metal ion binding; GO:0061630|ubiquitin protein ligase activity	--	--	1976	XP_414581.2	XP_414581.2 LON peptidase N-terminal domain and RING finger protein 1 [Gallus gallus]	sp|D3YY23|LONF1_MOUSE	sp|D3YY23|LONF1_MOUSE LON peptidase N-terminal domain and RING finger protein 1 OS=Mus musculus GN=Lonrf1 PE=1 SV=2	9031.ENSGALP00000006474	annotation not avaliable	_	KOG4159	_	"PF02190.13|LON_substr_bdg|ATP-dependent protease La (LON) substrate-binding domain|ENSGALT00000006484|m.8834:446-639;PF13923.3|zf-C3HC4_2|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000006484|m.8834:357-395;PF13920.3|zf-C3HC4_3|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000006484|m.8834:355-400;PF00097.22|zf-C3HC4|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000006484|m.8834:358-395;PF13445.3|zf-RING_UBOX|RING-type zinc-finger|ENSGALT00000006484|m.8834:80-104;PF13445.3|zf-RING_UBOX|RING-type zinc-finger|ENSGALT00000006484|m.8834:358-393;PF13639.3|zf-RING_2|Ring finger domain|ENSGALT00000006484|m.8834:357-396"
ENSGALG00000004081	1.878237786	5.562809015	-1.561364257	1.02E-28	1.50E-27	down	yes	1.945026587	1.928735289	1.760951481	5.289239968	5.454115031	5.945072044	21	4788385	4825706	-	TMCO4	protein_coding	--	GO:0016021|integral component of membrane	--	--	--	3305	XP_417632.6	XP_417632.6 transmembrane and coiled-coil domain-containing protein 4 isoform X2 [Gallus gallus]	sp|Q5TGY1|TMCO4_HUMAN	sp|Q5TGY1|TMCO4_HUMAN Transmembrane and coiled-coil domain-containing protein 4 OS=Homo sapiens GN=TMCO4 PE=2 SV=1	_	_	_	_	_	PF05277.9|DUF726|Protein of unknown function (DUF726)|ENSGALT00000098361|m.4199:155-491
ENSGALG00000004106	72.92209466	30.02300478	1.280005007	9.92E-78	7.68E-76	up	yes	70.72396668	76.1894223	71.85289501	28.04523767	31.90009001	30.12368666	5	1895074	1901741	+	DHCR7	protein_coding	GO:0001568|blood vessel development; GO:0006695|cholesterol biosynthetic process; GO:0009791|post-embryonic development; GO:0016126|sterol biosynthetic process; GO:0016132|brassinosteroid biosynthetic process; GO:0030154|cell differentiation; GO:0030324|lung development; GO:0035264|multicellular organism growth; GO:0042127|regulation of cell population proliferation; GO:0045540|regulation of cholesterol biosynthetic process	GO:0005640|nuclear outer membrane; GO:0005783|endoplasmic reticulum; GO:0005829|cytosol; GO:0016020|membrane; GO:0030176|integral component of endoplasmic reticulum membrane	GO:0009918|sterol delta7 reductase activity; GO:0047598|7-dehydrocholesterol reductase activity; GO:0050661|NADP binding	ko:K00213|DHCR7	ko00100|Steroid biosynthesis; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites	2583	NP_001186419.1	NP_001186419.1 7-dehydrocholesterol reductase [Gallus gallus]	sp|O88455|DHCR7_MOUSE	sp|O88455|DHCR7_MOUSE 7-dehydrocholesterol reductase OS=Mus musculus GN=Dhcr7 PE=1 SV=1	9031.ENSGALP00000006521	7-dehydrocholesterol reductase	_	KOG1435	_	PF01222.14|ERG4_ERG24|Ergosterol biosynthesis ERG4/ERG24 family|ENSGALT00000006531|m.2248:82-474
ENSGALG00000004121	0.399766903	0.018189265	3.861585702	2.02E-09	8.47E-09	up	yes	0.373191525	0.338773005	0.48733618	0	0.028113502	0.026454293	4	1395651	1409355	+	LPAR4	protein_coding	GO:0035025|positive regulation of Rho protein signal transduction; GO:0051482|positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane	GO:0035727|lysophosphatidic acid binding; GO:0070915|lysophosphatidic acid receptor activity	"ko:K04275|LPAR4,GPR23"	ko04015|Rap1 signaling pathway; ko04072|Phospholipase D signaling pathway; ko04080|Neuroactive ligand-receptor interaction; ko04151|PI3K-Akt signaling pathway; ko05200|Pathways in cancer	2730	NP_001264978.1	NP_001264978.1 lysophosphatidic acid receptor 4 [Gallus gallus]	sp|Q8BLG2|LPAR4_MOUSE	sp|Q8BLG2|LPAR4_MOUSE Lysophosphatidic acid receptor 4 OS=Mus musculus GN=Lpar4 PE=2 SV=2	9031.ENSGALP00000006553	G protein-coupled receptor 23	_	KOG3656	_	PF00001.18|7tm_1|7 transmembrane receptor (rhodopsin family)|ENSGALT00000059797|m.15963:35-290;PF10320.6|7TM_GPCR_Srsx|Serpentine type 7TM GPCR chemoreceptor Srsx|ENSGALT00000059797|m.15963:29-301
ENSGALG00000004128	1.571307592	4.895988501	-1.633425828	2.59E-14	1.63E-13	down	yes	2.104867914	1.322820842	1.28623402	5.768407839	4.985657405	3.933900259	4	1346530	1359078	-	CYSLTR1	protein_coding	GO:0002437|inflammatory response to antigenic stimulus; GO:0003013|circulatory system process; GO:0006816|calcium ion transport; GO:0006935|chemotaxis; GO:0007166|cell surface receptor signaling pathway; GO:0007200|phospholipase C-activating G protein-coupled receptor signaling pathway; GO:0007218|neuropeptide signaling pathway	GO:0005887|integral component of plasma membrane	GO:0004974|leukotriene receptor activity; GO:0008528|G protein-coupled peptide receptor activity	ko:K04322|CYSLTR1	ko04020|Calcium signaling pathway; ko04080|Neuroactive ligand-receptor interaction	2278	XP_025005925.1	XP_025005925.1 cysteinyl leukotriene receptor 1 isoform X2 [Gallus gallus]	sp|Q99JA4|CLTR1_MOUSE	sp|Q99JA4|CLTR1_MOUSE Cysteinyl leukotriene receptor 1 OS=Mus musculus GN=Cysltr1 PE=1 SV=1	9031.ENSGALP00000006561	cysteinyl leukotriene receptor 1	_	KOG3656	_	PF00001.18|7tm_1|7 transmembrane receptor (rhodopsin family)|ENSGALT00000006571|m.15959:116-370;PF10328.6|7TM_GPCR_Srx|Serpentine type 7TM GPCR chemoreceptor Srx|ENSGALT00000006571|m.15959:108-311;PF10324.6|7TM_GPCR_Srw|Serpentine type 7TM GPCR chemoreceptor Srw|ENSGALT00000006571|m.15959:108-378;PF10323.6|7TM_GPCR_Srv|Serpentine type 7TM GPCR chemoreceptor Srv|ENSGALT00000006571|m.15959:132-322
ENSGALG00000004146	6.849997147	2.964492342	1.205564512	4.22E-11	2.06E-10	up	yes	7.190506567	6.6549278	6.704557074	2.689916258	3.527578841	2.675981928	20	5277690	5321475	+	RIMS4	protein_coding	GO:0042391|regulation of membrane potential; GO:0048791|calcium ion-regulated exocytosis of neurotransmitter; GO:2000300|regulation of synaptic vesicle exocytosis	GO:0030054|cell junction; GO:0048786|presynaptic active zone; GO:0097060|synaptic membrane	GO:0044325|ion channel binding	"ko:K15299|RIMS4,RIM4"	--	1341	XP_025751038.1	XP_025751038.1 LOW QUALITY PROTEIN: regulating synaptic membrane exocytosis protein 4 [Manacus vitellinus]	sp|Q9H426|RIMS4_HUMAN	sp|Q9H426|RIMS4_HUMAN Regulating synaptic membrane exocytosis protein 4 OS=Homo sapiens GN=RIMS4 PE=1 SV=3	_	_	_	_	_	PF00168.27|C2|C2 domain|ENSGALT00000006595|m.3028:305-412
ENSGALG00000004150	5.242442138	18.66025841	-1.829681627	5.12E-60	2.53E-58	down	yes	5.807255836	5.307180517	4.612890062	16.34954928	21.68579603	17.94542992	10	7185220	7263560	+	MYO1E	protein_coding	GO:0001570|vasculogenesis; GO:0001701|in utero embryonic development; GO:0003094|glomerular filtration; GO:0006807|nitrogen compound metabolic process; GO:0006897|endocytosis; GO:0030048|actin filament-based movement; GO:0032836|glomerular basement membrane development; GO:0035166|post-embryonic hemopoiesis; GO:0048008|platelet-derived growth factor receptor signaling pathway; GO:0072015|glomerular visceral epithelial cell development	GO:0005737|cytoplasm; GO:0005856|cytoskeleton; GO:0005903|brush border; GO:0005911|cell-cell junction; GO:0005912|adherens junction; GO:0015629|actin cytoskeleton; GO:0016459|myosin complex; GO:0030136|clathrin-coated vesicle; GO:0070062|extracellular exosome	"GO:0000146|microfilament motor activity; GO:0003774|motor activity; GO:0005516|calmodulin binding; GO:0005524|ATP binding; GO:0035091|phosphatidylinositol binding; GO:0042623|ATPase activity, coupled; GO:0051015|actin filament binding"	ko:K10356|MYO1	--	4455	XP_004943823.1	XP_004943823.1 unconventional myosin-Ie isoform X2 [Gallus gallus]	sp|Q12965|MYO1E_HUMAN	sp|Q12965|MYO1E_HUMAN Unconventional myosin-Ie OS=Homo sapiens GN=MYO1E PE=1 SV=2	59729.ENSTGUP00000006142	Myosin-Ie (Myosin-Ic) [Taeniopygia guttata]	COG5022	KOG0162	_	"PF00063.18|Myosin_head|Myosin head (motor domain)|ENSGALT00000006599|m.5417:21-679;PF06017.10|Myosin_TH1|Unconventional myosin tail, actin- and lipid-binding|ENSGALT00000006599|m.5417:719-920;PF00018.25|SH3_1|SH3 domain|ENSGALT00000006599|m.5417:1058-1102;PF14604.3|SH3_9|Variant SH3 domain|ENSGALT00000006599|m.5417:1059-1107;PF07653.14|SH3_2|Variant SH3 domain|ENSGALT00000006599|m.5417:1057-1108"
ENSGALG00000004173	0.423256729	1.114200845	-1.375605742	1.91E-05	5.19E-05	down	yes	0.363665492	0.444399758	0.461704938	0.94994525	1.174598379	1.218058906	8	6534561	6542774	-	ENSGALG00000004173	protein_coding	--	--	--	--	--	2608	XP_025008809.1	XP_025008809.1 axonemal dynein light chain domain-containing protein 1 [Gallus gallus]	sp|Q95LP5|AXDN1_MACFA	sp|Q95LP5|AXDN1_MACFA Axonemal dynein light chain domain-containing protein 1 OS=Macaca fascicularis GN=AXDND1 PE=2 SV=2	_	_	_	_	_	PF10211.6|Ax_dynein_light|Axonemal dynein light chain|ENSGALT00000006634|m.7197:29-191
ENSGALG00000004203	22.58570259	8.298591321	1.443372615	1.91E-32	3.43E-31	up	yes	24.37192362	22.54722303	20.83796112	8.977545301	8.368327861	7.549900802	14	3023831	3027172	-	PSMG3	protein_coding	--	--	--	"ko:K11877|PSMG3,PAC3"	--	1087	NP_001264468.1	NP_001264468.1 proteasome assembly chaperone 3 [Gallus gallus]	sp|Q9BT73|PSMG3_HUMAN	sp|Q9BT73|PSMG3_HUMAN Proteasome assembly chaperone 3 OS=Homo sapiens GN=PSMG3 PE=1 SV=1	_	_	_	_	_	PF10178.6|PAC3|Proteasome assembly chaperone 3|ENSGALT00000006688|m.9292:108-193
ENSGALG00000004228	9.500076079	29.4612337	-1.631778667	2.41E-112	4.15E-110	down	yes	9.21920505	9.772813229	9.508209959	28.94348959	28.93866449	30.50154703	7	5903680	5932487	+	USP40	protein_coding	GO:0006511|ubiquitin-dependent protein catabolic process; GO:0016579|protein deubiquitination	--	GO:0036459|thiol-dependent ubiquitinyl hydrolase activity	ko:K11869|USP40	--	3795	NP_001244247.1	NP_001244247.1 ubiquitin carboxyl-terminal hydrolase 40 [Gallus gallus]	sp|Q9NVE5|UBP40_HUMAN	sp|Q9NVE5|UBP40_HUMAN Ubiquitin carboxyl-terminal hydrolase 40 OS=Homo sapiens GN=USP40 PE=1 SV=3	9031.ENSGALP00000006720	ubiquitin specific peptidase 40	COG5077	KOG1863	_	PF00443.26|UCH|Ubiquitin carboxyl-terminal hydrolase|ENSGALT00000006731|m.5755:62-345;PF13423.3|UCH_1|Ubiquitin carboxyl-terminal hydrolase|ENSGALT00000006731|m.5755:61-341
ENSGALG00000004236	1.909326976	4.842756591	-1.338203988	2.04E-14	1.30E-13	down	yes	1.790931472	1.693224027	2.243825429	4.759908849	4.883589344	4.884771579	7	5942946	5979718	+	TRAF3IP1	protein_coding	GO:0001738|morphogenesis of a polarized epithelium; GO:0001822|kidney development; GO:0001933|negative regulation of protein phosphorylation; GO:0021532|neural tube patterning; GO:0031076|embryonic camera-type eye development; GO:0031333|negative regulation of protein complex assembly; GO:0032480|negative regulation of type I interferon production; GO:0032688|negative regulation of interferon-beta production; GO:0035050|embryonic heart tube development; GO:0036342|post-anal tail morphogenesis; GO:0042073|intraciliary transport; GO:0042733|embryonic digit morphogenesis; GO:0050687|negative regulation of defense response to virus; GO:0060271|cilium assembly; GO:0070507|regulation of microtubule cytoskeleton organization; GO:1901621|negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning	GO:0005737|cytoplasm; GO:0005813|centrosome; GO:0005929|cilium; GO:0005930|axoneme; GO:0030992|intraciliary transport particle B; GO:0035869|ciliary transition zone; GO:0036064|ciliary basal body; GO:0097542|ciliary tip; GO:0097546|ciliary base	GO:0008017|microtubule binding	"ko:K19680|TRAF3IP1,IFT54"	--	2236	XP_003641610.2	XP_003641610.2 TRAF3-interacting protein 1 isoform X3 [Gallus gallus]	sp|Q5XIN3|MIPT3_RAT	sp|Q5XIN3|MIPT3_RAT TRAF3-interacting protein 1 OS=Rattus norvegicus GN=Traf3ip1 PE=1 SV=1	_	_	_	_	_	PF10243.6|MIP-T3|Microtubule-binding protein MIP-T3|ENSGALT00000006741|m.5756:68-660
ENSGALG00000004240	11.59413565	5.302130551	1.127276558	4.95E-24	5.84E-23	up	yes	10.3315861	11.33022702	13.12059384	5.512862773	5.697197187	4.696331694	15	5872047	5889264	+	ORAI1	protein_coding	GO:0002115|store-operated calcium entry; GO:0002250|adaptive immune response; GO:0051928|positive regulation of calcium ion transport	GO:0005887|integral component of plasma membrane; GO:0016020|membrane	GO:0015279|store-operated calcium channel activity	ko:K16056|ORAI1	ko04020|Calcium signaling pathway; ko04024|cAMP signaling pathway; ko04611|Platelet activation; ko04924|Renin secretion; ko04925|Aldosterone synthesis and secretion; ko05340|Primary immunodeficiency	3372	XP_015733624.1	XP_015733624.1 PREDICTED: calcium release-activated calcium channel protein 1 isoform X1 [Coturnix japonica]	sp|Q5ZL05|CRCM1_CHICK	sp|Q5ZL05|CRCM1_CHICK Calcium release-activated calcium channel protein 1 OS=Gallus gallus GN=ORAI1 PE=2 SV=1	9031.ENSGALP00000006734	Calcium release-activated calcium channel protein 1 (Protein orai-1)(Transmembrane protein 1 [...] 	_	KOG4298	_	PF07856.9|Orai-1|Mediator of CRAC channel activity|ENSGALT00000092866|m.10523:30-212
ENSGALG00000004246	6.589556802	2.552820202	1.364636875	4.11E-17	3.19E-16	up	yes	7.197306126	6.79244625	5.778918031	2.460308224	2.981140414	2.217011966	19	6349841	6361974	-	SLC6A4	protein_coding	"GO:0001666|response to hypoxia; GO:0006837|serotonin transport; GO:0007584|response to nutrient; GO:0007613|memory; GO:0007623|circadian rhythm; GO:0009636|response to toxic substance; GO:0010628|positive regulation of gene expression; GO:0014064|positive regulation of serotonin secretion; GO:0015844|monoamine transport; GO:0021794|thalamus development; GO:0021941|negative regulation of cerebellar granule cell precursor proliferation; GO:0032227|negative regulation of synaptic transmission, dopaminergic; GO:0032355|response to estradiol; GO:0035176|social behavior; GO:0042136|neurotransmitter biosynthetic process; GO:0042310|vasoconstriction; GO:0042493|response to drug; GO:0042713|sperm ejaculation; GO:0045665|negative regulation of neuron differentiation; GO:0045787|positive regulation of cell cycle; GO:0046621|negative regulation of organ growth; GO:0048854|brain morphogenesis; GO:0051259|protein complex oligomerization; GO:0051260|protein homooligomerization; GO:0051583|dopamine uptake involved in synaptic transmission; GO:0051610|serotonin uptake; GO:0071300|cellular response to retinoic acid; GO:0071321|cellular response to cGMP"	GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0010008|endosome membrane; GO:0012505|endomembrane system; GO:0043005|neuron projection; GO:0045121|membrane raft; GO:0098793|presynapse	GO:0005330|dopamine:sodium symporter activity; GO:0005335|serotonin:sodium symporter activity; GO:0008504|monoamine transmembrane transporter activity; GO:0017022|myosin binding; GO:0017075|syntaxin-1 binding; GO:0017137|Rab GTPase binding; GO:0019811|cocaine binding; GO:0042803|protein homodimerization activity; GO:0046872|metal ion binding; GO:0050998|nitric-oxide synthase binding; GO:0051015|actin filament binding	ko:K05037|SLC6A4	ko04726|Serotonergic synapse	2167	XP_015151185.1	XP_015151185.1 sodium-dependent serotonin transporter isoform X1 [Gallus gallus]	sp|P31645|SC6A4_HUMAN	sp|P31645|SC6A4_HUMAN Sodium-dependent serotonin transporter OS=Homo sapiens GN=SLC6A4 PE=1 SV=1	9031.ENSGALP00000006742	"solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 "	COG0733	KOG3659	_	"PF00209.15|SNF|Sodium:neurotransmitter symporter family|ENSGALT00000006753|m.14014:119-638;PF03491.10|5HT_transport_N|Serotonin (5-HT) neurotransmitter transporter, N-terminus|ENSGALT00000006753|m.14014:50-74"
ENSGALG00000004270	1.731806237	5.609130608	-1.68976279	1.06E-34	2.08E-33	down	yes	1.64329863	1.680182875	1.871937205	5.506405616	5.491514059	5.829472148	10	7557497	7611673	+	ALDH1A2	protein_coding	GO:0001568|blood vessel development; GO:0001936|regulation of endothelial cell proliferation; GO:0001947|heart looping; GO:0003007|heart morphogenesis; GO:0008284|positive regulation of cell population proliferation; GO:0008285|negative regulation of cell population proliferation; GO:0009952|anterior/posterior pattern specification; GO:0009954|proximal/distal pattern formation; GO:0010628|positive regulation of gene expression; GO:0014032|neural crest cell development; GO:0016331|morphogenesis of embryonic epithelium; GO:0021522|spinal cord motor neuron differentiation; GO:0021915|neural tube development; GO:0030324|lung development; GO:0030900|forebrain development; GO:0030902|hindbrain development; GO:0031016|pancreas development; GO:0031076|embryonic camera-type eye development; GO:0034097|response to cytokine; GO:0035115|embryonic forelimb morphogenesis; GO:0035799|ureter maturation; GO:0042572|retinol metabolic process; GO:0042574|retinal metabolic process; GO:0042904|9-cis-retinoic acid biosynthetic process; GO:0043065|positive regulation of apoptotic process; GO:0048384|retinoic acid receptor signaling pathway; GO:0048566|embryonic digestive tract development; GO:0048738|cardiac muscle tissue development; GO:0060324|face development; GO:0071300|cellular response to retinoic acid	GO:0005737|cytoplasm	GO:0001758|retinal dehydrogenase activity; GO:0004028|3-chloroallyl aldehyde dehydrogenase activity; GO:0004029|aldehyde dehydrogenase (NAD) activity; GO:0004745|retinol dehydrogenase activity	ko:K07249|ALDH1A	ko00830|Retinol metabolism; ko01100|Metabolic pathways	3495	PKK25360.1	"PKK25360.1 aldehyde dehydrogenase 1 family, member A2, partial [Columba livia]"	sp|O93344|AL1A2_CHICK	sp|O93344|AL1A2_CHICK Retinal dehydrogenase 2 OS=Gallus gallus GN=ALDH1A2 PE=2 SV=2	9031.ENSGALP00000033786	Retinal dehydrogenase 2 (RALDH 2)(RalDH2)(EC 1.2.1.36)(Aldehyde dehydrogenase family 1 membe [...] 	COG1012	KOG2450	_	PF00171.19|Aldedh|Aldehyde dehydrogenase family|ENSGALT00000084591|m.5436:63-526
ENSGALG00000004285	14.52089588	6.75123052	1.103765912	2.30E-21	2.34E-20	up	yes	12.87371474	14.76412901	15.92484387	6.460137078	7.243006821	6.550547661	20	5418333	5446344	-	HNF4A	protein_coding	"GO:0006355|regulation of transcription, DNA-templated; GO:0006357|regulation of transcription by RNA polymerase II; GO:0006591|ornithine metabolic process; GO:0006629|lipid metabolic process; GO:0006637|acyl-CoA metabolic process; GO:0006805|xenobiotic metabolic process; GO:0007164|establishment of tissue polarity; GO:0007548|sex differentiation; GO:0007568|aging; GO:0007596|blood coagulation; GO:0008285|negative regulation of cell population proliferation; GO:0009749|response to glucose; GO:0010470|regulation of gastrulation; GO:0019216|regulation of lipid metabolic process; GO:0023019|signal transduction involved in regulation of gene expression; GO:0030154|cell differentiation; GO:0030308|negative regulation of cell growth; GO:0030336|negative regulation of cell migration; GO:0031667|response to nutrient levels; GO:0032496|response to lipopolysaccharide; GO:0032534|regulation of microvillus assembly; GO:0042493|response to drug; GO:0042532|negative regulation of tyrosine phosphorylation of STAT protein; GO:0042593|glucose homeostasis; GO:0042632|cholesterol homeostasis; GO:0043433|negative regulation of DNA-binding transcription factor activity; GO:0045216|cell-cell junction organization; GO:0045722|positive regulation of gluconeogenesis; GO:0045723|positive regulation of fatty acid biosynthetic process; GO:0045893|positive regulation of transcription, DNA-templated; GO:0045930|negative regulation of mitotic cell cycle; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0050796|regulation of insulin secretion; GO:0051591|response to cAMP; GO:0055088|lipid homeostasis; GO:0055091|phospholipid homeostasis; GO:0060395|SMAD protein signal transduction; GO:0070328|triglyceride homeostasis; GO:0070365|hepatocyte differentiation; GO:0071456|cellular response to hypoxia; GO:0071548|response to dexamethasone; GO:1902569|negative regulation of activation of Janus kinase activity"	GO:0005634|nucleus; GO:0005667|transcription factor complex; GO:0005737|cytoplasm	"GO:0000062|fatty-acyl-CoA binding; GO:0000979|RNA polymerase II core promoter sequence-specific DNA binding; GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0000987|proximal promoter sequence-specific DNA binding; GO:0001102|RNA polymerase II activating transcription factor binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity; GO:0003707|steroid hormone receptor activity; GO:0004879|nuclear receptor activity; GO:0005102|signaling receptor binding; GO:0005504|fatty acid binding; GO:0008134|transcription factor binding; GO:0008270|zinc ion binding; GO:0016290|palmitoyl-CoA hydrolase activity; GO:0036042|long-chain fatty acyl-CoA binding; GO:0042803|protein homodimerization activity; GO:0043565|sequence-specific DNA binding; GO:0044212|transcription regulatory region DNA binding; GO:0050544|arachidonic acid binding; GO:0070491|repressing transcription factor binding; GO:0070540|stearic acid binding"	"ko:K07292|NR2A1,HNF4A"	ko04152|AMPK signaling pathway; ko04950|Maturity onset diabetes of the young	1801	XP_015736953.1	XP_015736953.1 PREDICTED: hepatocyte nuclear factor 4-alpha isoform X2 [Coturnix japonica]	sp|P22449|HNF4A_RAT	sp|P22449|HNF4A_RAT Hepatocyte nuclear factor 4-alpha OS=Rattus norvegicus GN=Hnf4a PE=1 SV=3	9031.ENSGALP00000006799	hepatocyte nuclear factor 4 alpha 	_	KOG4215	_	"PF00104.27|Hormone_recep|Ligand-binding domain of nuclear hormone receptor|ENSGALT00000006810|m.3044:181-363;PF00105.15|zf-C4|Zinc finger, C4 type (two domains)|ENSGALT00000006810|m.3044:61-129"
ENSGALG00000004297	0.243032832	0.740996144	-1.56948091	1.51E-15	1.05E-14	down	yes	0.235572587	0.276950834	0.216575075	0.623326936	0.801566904	0.798094593	12	3442270	3511826	+	DNAH1	protein_coding	GO:0003351|epithelial cilium movement involved in extracellular fluid movement; GO:0030317|flagellated sperm motility; GO:0036159|inner dynein arm assembly; GO:0060294|cilium movement involved in cell motility	GO:0036126|sperm flagellum; GO:0036156|inner dynein arm	"GO:0003777|microtubule motor activity; GO:0005524|ATP binding; GO:0008569|ATP-dependent microtubule motor activity, minus-end-directed; GO:0045503|dynein light chain binding; GO:0045505|dynein intermediate chain binding; GO:0051959|dynein light intermediate chain binding"	ko:K10408|DNAH	ko05016|Huntington's disease	12973	XP_025010454.1	"XP_025010454.1 dynein heavy chain 1, axonemal [Gallus gallus]"	sp|E9Q8T7|DYH1_MOUSE	"sp|E9Q8T7|DYH1_MOUSE Dynein heavy chain 1, axonemal OS=Mus musculus GN=Dnah1 PE=2 SV=1"	9031.ENSGALP00000006832	"dynein, axonemal, heavy chain 1"	COG5245	KOG3595	_	"PF03028.12|Dynein_heavy|Dynein heavy chain and region D6 of dynein motor|ENSGALT00000006843|m.7345:3608-4306;PF08393.10|DHC_N2|Dynein heavy chain, N-terminal region 2|ENSGALT00000006843|m.7345:1061-1462;PF12774.4|AAA_6|Hydrolytic ATP binding site of dynein motor region D1|ENSGALT00000006843|m.7345:1590-1820;PF12781.4|AAA_9|ATP-binding dynein motor region D5|ENSGALT00000006843|m.7345:3246-3470;PF12780.4|AAA_8|P-loop containing dynein motor region D4|ENSGALT00000006843|m.7345:2599-2862;PF12777.4|MT|Microtubule-binding stalk of dynein motor|ENSGALT00000006843|m.7345:2876-3219;PF12775.4|AAA_7|P-loop containing dynein motor region D3|ENSGALT00000006843|m.7345:2234-2516;PF07728.11|AAA_5|AAA domain (dynein-related subfamily)|ENSGALT00000006843|m.7345:1905-2049"
ENSGALG00000004306	0.331975745	0.717251711	-1.088560782	0.023582513	0.038574185	down	yes	0.145958696	0.198745936	0.651222604	0.564707303	0.725699928	0.861347904	5	1709027	1716094	-	SYT12	protein_coding	GO:0006906|vesicle fusion; GO:0017158|regulation of calcium ion-dependent exocytosis; GO:0046928|regulation of neurotransmitter secretion; GO:0048791|calcium ion-regulated exocytosis of neurotransmitter; GO:0048792|spontaneous exocytosis of neurotransmitter; GO:0060291|long-term synaptic potentiation	GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0030054|cell junction; GO:0030672|synaptic vesicle membrane	GO:0005509|calcium ion binding; GO:0005544|calcium-dependent phospholipid binding; GO:0019905|syntaxin binding; GO:0030276|clathrin binding	ko:K19912|SYT12	--	2527	NP_001186441.1	NP_001186441.1 synaptotagmin-12 [Gallus gallus]	sp|P97610|SYT12_RAT	sp|P97610|SYT12_RAT Synaptotagmin-12 OS=Rattus norvegicus GN=Syt12 PE=1 SV=1	9031.ENSGALP00000006848	synaptotagmin XII	_	KOG1028	_	PF00168.27|C2|C2 domain|ENSGALT00000006859|m.2224:165-258;PF00168.27|C2|C2 domain|ENSGALT00000006859|m.2224:295-398
ENSGALG00000004322	1.619049423	9.155811148	-2.492232187	4.47E-62	2.34E-60	down	yes	2.0202801	1.561339834	1.275528336	8.968480688	8.846733902	9.652218853	7	6622423	6635326	+	AHR1B	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0007049|cell cycle; GO:0009410|response to xenobiotic stimulus; GO:0032922|circadian regulation of gene expression; GO:0045892|negative regulation of transcription, DNA-templated; GO:0045893|positive regulation of transcription, DNA-templated"	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0034751|aryl hydrocarbon receptor complex	GO:0003700|DNA-binding transcription factor activity; GO:0046983|protein dimerization activity; GO:0070888|E-box binding	ko:K09093|AHR	ko04659|Th17 cell differentiation	2895	NP_001305922.1	NP_001305922.1 aryl hydrocarbon receptor 1 beta [Gallus gallus]	sp|Q95LD9|AHR_DELLE	sp|Q95LD9|AHR_DELLE Aryl hydrocarbon receptor OS=Delphinapterus leucas GN=AHR PE=2 SV=1	9031.ENSGALP00000006877	annotation not avaliable	_	KOG3560	_	PF08447.9|PAS_3|PAS fold|ENSGALT00000006888|m.5763:289-372;PF14598.3|PAS_11|PAS domain|ENSGALT00000006888|m.5763:277-374;PF00989.22|PAS|PAS fold|ENSGALT00000006888|m.5763:106-173
ENSGALG00000004339	1.013418107	8.379887731	-3.035255842	6.51E-73	4.52E-71	down	yes	0.802995262	1.380902368	0.85635669	7.737849184	9.365772784	8.036041227	Z	23210259	23289222	-	ENSGALG00000004339	protein_coding	GO:0006198|cAMP catabolic process; GO:0007165|signal transduction; GO:0009187|cyclic nucleotide metabolic process; GO:0046676|negative regulation of insulin secretion	GO:0005829|cytosol	"GO:0004114|3',5'-cyclic-nucleotide phosphodiesterase activity; GO:0004115|3',5'-cyclic-AMP phosphodiesterase activity; GO:0046872|metal ion binding"	ko:K18437|PDE8	ko00230|Purine metabolism; ko05032|Morphine addiction	3609	XP_004937385.1	"XP_004937385.1 high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1 [Gallus gallus]"	sp|O95263|PDE8B_HUMAN	"sp|O95263|PDE8B_HUMAN High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B OS=Homo sapiens GN=PDE8B PE=1 SV=2"	_	_	_	_	_	PF00233.16|PDEase_I|3'5'-cyclic nucleotide phosphodiesterase|ENSGALT00000038586|m.10969:598-850;PF08629.7|PDE8|PDE8 phosphodiesterase|ENSGALT00000038586|m.10969:1-46;PF13426.4|PAS_9|PAS domain|ENSGALT00000038586|m.10969:261-356;PF00989.22|PAS|PAS fold|ENSGALT00000038586|m.10969:255-356;PF08447.9|PAS_3|PAS fold|ENSGALT00000038586|m.10969:274-356;PF08448.7|PAS_4|PAS fold|ENSGALT00000038586|m.10969:256-351
ENSGALG00000004360	0.060545689	0.541298368	-2.966203506	2.95E-06	8.89E-06	down	yes	0.073080567	0.071443647	0.037112852	0.522293338	0.539524483	0.562077284	13	13729635	13735808	-	ENSGALG00000004360	protein_coding	--	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0015171|amino acid transmembrane transporter activity	"ko:K13864|SLC7A2,ATRC2"	--	2163	XP_015149405.1	XP_015149405.1 cationic amino acid transporter 2 isoform X1 [Gallus gallus]	sp|Q6DCE8|CTR2_XENLA	sp|Q6DCE8|CTR2_XENLA Cationic amino acid transporter 2 OS=Xenopus laevis GN=slc7a2 PE=2 SV=1	_	_	_	_	_	PF13520.3|AA_permease_2|Amino acid permease|ENSGALT00000006953|m.8855:33-426;PF00324.18|AA_permease|Amino acid permease|ENSGALT00000006953|m.8855:38-434;PF13906.3|AA_permease_C|C-terminus of AA_permease|ENSGALT00000006953|m.8855:535-585
ENSGALG00000004365	3.993411167	10.890863	-1.445140655	5.65E-32	9.94E-31	down	yes	3.809227359	3.501793988	4.669212154	11.16446773	10.95870745	10.5494138	15	5996365	6006391	+	ENSGALG00000004365	protein_coding	GO:0003341|cilium movement	GO:0005737|cytoplasm; GO:0005930|axoneme; GO:0031514|motile cilium	--	--	--	2725	XP_025011449.1	XP_025011449.1 cilia- and flagella-associated protein 251 [Gallus gallus]	sp|Q8TBY9|CF251_HUMAN	sp|Q8TBY9|CF251_HUMAN Cilia- and flagella-associated protein 251 OS=Homo sapiens GN=WDR66 PE=2 SV=2	9031.ENSGALP00000006952	WD repeat domain 66	_	KOG2106	NOG129377	_
ENSGALG00000004394	1.212684569	2.479051965	-1.025544088	6.10E-05	0.000154246	down	yes	1.570088009	1.034119733	1.033845966	2.462442321	2.904848864	2.06986471	7	6712367	6730379	+	ENSGALG00000004394	protein_coding	GO:0016071|mRNA metabolic process	GO:0005634|nucleus; GO:0005829|cytosol; GO:0070062|extracellular exosome; GO:1990904|ribonucleoprotein complex	"GO:0001227|DNA-binding transcription repressor activity, RNA polymerase II-specific; GO:0003690|double-stranded DNA binding; GO:0003723|RNA binding; GO:1990829|C-rich single-stranded DNA binding"	ko:K21444|PCBP3_4	--	1688	XP_013057433.1	XP_013057433.1 PREDICTED: poly(rC)-binding protein 3 isoform X5 [Anser cygnoides domesticus]	sp|P57721|PCBP3_HUMAN	sp|P57721|PCBP3_HUMAN Poly(rC)-binding protein 3 OS=Homo sapiens GN=PCBP3 PE=2 SV=2	_	_	_	_	_	PF00013.26|KH_1|KH domain|ENSGALT00000100323|m.5767:1-44;PF00013.26|KH_1|KH domain|ENSGALT00000100323|m.5767:68-131;PF07650.14|KH_2|KH domain|ENSGALT00000100323|m.5767:47-101
ENSGALG00000004397	54.01424681	116.8588106	-1.113211003	5.89E-82	5.01E-80	down	yes	54.64261092	55.24861991	52.1515096	114.640915	119.7029421	116.2325747	15	6029841	6070325	+	MLXIP	protein_coding	GO:0045944|positive regulation of transcription by RNA polymerase II; GO:1900402|regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter	GO:0005634|nucleus; GO:0005741|mitochondrial outer membrane	"GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003700|DNA-binding transcription factor activity; GO:0046983|protein dimerization activity"	ko:K09113|MLX	ko04931|Insulin resistance; ko04932|Non-alcoholic fatty liver disease (NAFLD)	2646	XP_015131065.1	XP_015131065.1 MLX-interacting protein isoform X1 [Gallus gallus]	sp|Q9HAP2|MLXIP_HUMAN	sp|Q9HAP2|MLXIP_HUMAN MLX-interacting protein OS=Homo sapiens GN=MLXIP PE=1 SV=2	9031.ENSGALP00000006999	MLX interacting protein	_	KOG3582	_	PF00010.23|HLH|Helix-loop-helix DNA-binding domain|ENSGALT00000007010|m.10539:682-732
ENSGALG00000004398	0.124063999	0.352417423	-1.434730441	0.002445004	0.004832812	down	yes	0.201591924	0.055427765	0.115172308	0.284356638	0.463424051	0.309471579	14	3830739	3870033	-	CARD11	protein_coding	GO:0001819|positive regulation of cytokine production; GO:0002223|stimulatory C-type lectin receptor signaling pathway; GO:0002377|immunoglobulin production; GO:0030183|B cell differentiation; GO:0030890|positive regulation of B cell proliferation; GO:0031295|T cell costimulation; GO:0038095|Fc-epsilon receptor signaling pathway; GO:0042100|B cell proliferation; GO:0042102|positive regulation of T cell proliferation; GO:0042981|regulation of apoptotic process; GO:0043123|positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0045061|thymic T cell selection; GO:0045086|positive regulation of interleukin-2 biosynthetic process; GO:0045577|regulation of B cell differentiation; GO:0045580|regulation of T cell differentiation; GO:0048872|homeostasis of number of cells; GO:0050852|T cell receptor signaling pathway; GO:0051092|positive regulation of NF-kappaB transcription factor activity; GO:0070970|interleukin-2 secretion	GO:0001772|immunological synapse; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0045121|membrane raft; GO:0070062|extracellular exosome	GO:0004385|guanylate kinase activity; GO:0050700|CARD domain binding	ko:K07367|CARD11	ko04064|NF-kappa B signaling pathway; ko04660|T cell receptor signaling pathway; ko04662|B cell receptor signaling pathway	4172	NP_001006161.2	NP_001006161.2 caspase recruitment domain-containing protein 11 [Gallus gallus]	sp|Q9BXL7|CAR11_HUMAN	sp|Q9BXL7|CAR11_HUMAN Caspase recruitment domain-containing protein 11 OS=Homo sapiens GN=CARD11 PE=1 SV=3	9031.ENSGALP00000007002	Putative uncharacterized protein 	_	KOG0708	NOG47732	PF00619.18|CARD|Caspase recruitment domain|ENSGALT00000007013|m.9328:25-110
ENSGALG00000004413	5.626578083	2.598805088	1.111430421	2.04E-09	8.55E-09	up	yes	5.412920829	5.608983066	5.857830352	1.758074262	2.812256028	3.226084975	18	8903444	8963934	-	SLC39A11	protein_coding	GO:0071577|zinc ion transmembrane transport	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005794|Golgi apparatus; GO:0005886|plasma membrane; GO:0016020|membrane; GO:0016021|integral component of membrane	GO:0005385|zinc ion transmembrane transporter activity	"ko:K14717|SLC39A11,ZIP11"	--	2310	XP_021270558.1	XP_021270558.1 zinc transporter ZIP11 isoform X1 [Numida meleagris]	sp|Q8N1S5|S39AB_HUMAN	sp|Q8N1S5|S39AB_HUMAN Zinc transporter ZIP11 OS=Homo sapiens GN=SLC39A11 PE=2 SV=3	9031.ENSGALP00000007021	"solute carrier family 39 (metal ion transporter), member 11"	COG0428	KOG2474	_	PF02535.19|Zip|ZIP Zinc transporter|ENSGALT00000007033|m.12901:48-355
ENSGALG00000004436	3.768542842	11.23543468	-1.573437542	3.30E-41	8.86E-40	down	yes	3.585488312	4.157635842	3.562504373	10.77473995	11.07464288	11.85692121	14	4288119	4299512	+	CYP3A4	protein_coding	GO:0008202|steroid metabolic process; GO:0042445|hormone metabolic process; GO:0042448|progesterone metabolic process; GO:1901615|organic hydroxy compound metabolic process	GO:0005789|endoplasmic reticulum membrane; GO:0031090|organelle membrane	GO:0004497|monooxygenase activity; GO:0005506|iron ion binding; GO:0008395|steroid hydroxylase activity; GO:0020037|heme binding; GO:0050649|testosterone 6-beta-hydroxylase activity; GO:0070330|aromatase activity	ko:K07424|CYP3A	ko00140|Steroid hormone biosynthesis; ko00591|Linoleic acid metabolism; ko00830|Retinol metabolism; ko01100|Metabolic pathways; ko05204|Chemical carcinogenesis	2704	NP_001316437.1	NP_001316437.1 cytochrome P450 3A80 [Gallus gallus]	sp|P24463|CP3AC_CANLF	sp|P24463|CP3AC_CANLF Cytochrome P450 3A12 OS=Canis lupus familiaris GN=CYP3A12 PE=2 SV=1	9031.ENSGALP00000007048	cytochrome P450 3A80	COG2124	KOG0158	_	PF00067.19|p450|Cytochrome P450|ENSGALT00000007060|m.9330:73-534
ENSGALG00000004437	2.517023149	5.643119577	-1.161608334	2.67E-10	1.22E-09	down	yes	2.941992691	1.919793721	2.689283033	5.544192356	5.724652994	5.660513382	Z	22593889	22715686	+	LHFPL2	protein_coding	GO:0002576|platelet degranulation; GO:0007338|single fertilization; GO:0046545|development of primary female sexual characteristics; GO:0046546|development of primary male sexual characteristics; GO:1905516|positive regulation of fertilization	GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0031092|platelet alpha granule membrane	--	--	--	1729	XP_025000869.1	XP_025000869.1 LHFPL tetraspan subfamily member 2 protein [Gallus gallus]	sp|Q6ZUX7|LHPL2_HUMAN	sp|Q6ZUX7|LHPL2_HUMAN LHFPL tetraspan subfamily member 2 protein OS=Homo sapiens GN=LHFPL2 PE=2 SV=2	9031.ENSGALP00000007049	lipoma HMGIC fusion partner-like 2	_	KOG4026	_	PF10242.6|L_HMGIC_fpl|Lipoma HMGIC fusion partner-like protein|ENSGALT00000007061|m.10951:9-204
ENSGALG00000004491	0.64591881	1.824819582	-1.484049056	7.05E-08	2.55E-07	down	yes	0.408156721	0.641273277	0.888326432	1.820396447	1.860225092	1.793837206	Z	22452215	22497335	+	DMGDH	protein_coding	GO:0006579|amino-acid betaine catabolic process; GO:0019695|choline metabolic process; GO:0042426|choline catabolic process	GO:0005739|mitochondrion; GO:0005759|mitochondrial matrix	GO:0003723|RNA binding; GO:0009055|electron transfer activity; GO:0047865|dimethylglycine dehydrogenase activity	ko:K00315|DMGDH	"ko00260|Glycine, serine and threonine metabolism; ko01100|Metabolic pathways"	2711	XP_003643002.1	"XP_003643002.1 dimethylglycine dehydrogenase, mitochondrial [Gallus gallus]"	sp|Q9UI17|M2GD_HUMAN	"sp|Q9UI17|M2GD_HUMAN Dimethylglycine dehydrogenase, mitochondrial OS=Homo sapiens GN=DMGDH PE=1 SV=2"	9031.ENSGALP00000007139	annotation not avaliable	COG0404;COG0665	KOG2844	_	"PF01571.18|GCV_T|Aminomethyltransferase folate-binding domain|ENSGALT00000007151|m.10947:481-746;PF01266.21|DAO|FAD dependent oxidoreductase|ENSGALT00000007151|m.10947:53-416;PF08669.8|GCV_T_C|Glycine cleavage T-protein C-terminal barrel domain|ENSGALT00000007151|m.10947:755-846;PF16350.2|FAO_M|FAD dependent oxidoreductase central domain|ENSGALT00000007151|m.10947:419-472;PF04268.9|SoxG|Sarcosine oxidase, gamma subunit family|ENSGALT00000007151|m.10947:575-703;PF00890.21|FAD_binding_2|FAD binding domain|ENSGALT00000007151|m.10947:53-97"
ENSGALG00000004518	2.460239124	5.177681319	-1.070439153	3.10E-08	1.17E-07	down	yes	1.955142453	2.819240551	2.606334368	5.393104137	5.167898822	4.972040998	Z	22436116	22452194	-	ENSGALG00000004518	protein_coding	GO:0006577|amino-acid betaine metabolic process; GO:0006579|amino-acid betaine catabolic process; GO:0009086|methionine biosynthetic process; GO:0071267|L-methionine salvage	GO:0005829|cytosol; GO:0070062|extracellular exosome	GO:0008270|zinc ion binding; GO:0047150|betaine-homocysteine S-methyltransferase activity	ko:K00544|BHMT	"ko00260|Glycine, serine and threonine metabolism; ko00270|Cysteine and methionine metabolism; ko01100|Metabolic pathways"	1617	XP_414685.1	XP_414685.1 betaine--homocysteine S-methyltransferase 1 [Gallus gallus]	sp|O35490|BHMT1_MOUSE	sp|O35490|BHMT1_MOUSE Betaine--homocysteine S-methyltransferase 1 OS=Mus musculus GN=Bhmt PE=1 SV=1	9031.ENSGALP00000007182	betaine--homocysteine S-methyltransferase	COG0646	KOG1579	_	PF02574.13|S-methyl_trans|Homocysteine S-methyltransferase|ENSGALT00000007194|m.10943:25-315
ENSGALG00000004526	0.362785881	0.844308993	-1.196410748	0.000114736	0.000278551	down	yes	0.208048772	0.313111583	0.567197288	0.848472462	0.853139907	0.83131461	8	7387437	7436311	+	TNR	protein_coding	GO:0007155|cell adhesion; GO:0050767|regulation of neurogenesis	GO:0031012|extracellular matrix	--	ko:K06252|TN	ko04151|PI3K-Akt signaling pathway; ko04510|Focal adhesion; ko04512|ECM-receptor interaction; ko05206|MicroRNAs in cancer	4812	NP_990607.2	NP_990607.2 tenascin-R precursor [Gallus gallus]	sp|Q00546|TENR_CHICK	sp|Q00546|TENR_CHICK Tenascin-R OS=Gallus gallus GN=TNR PE=1 SV=1	9031.ENSGALP00000007195	Tenascin-R Precursor (TN-R)(Restrictin); Neural extracellular matrix (ECM) protein involved  [...] 	_	KOG1225;KOG2579	_	"PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000084303|m.7249:327-399;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000084303|m.7249:416-493;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000084303|m.7249:506-583;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000084303|m.7249:594-670;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000084303|m.7249:687-759;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000084303|m.7249:775-849;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000084303|m.7249:863-937;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000084303|m.7249:951-1022;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000084303|m.7249:1037-1110;PF00147.15|Fibrinogen_C|Fibrinogen beta and gamma chains, C-terminal globular domain|ENSGALT00000084303|m.7249:1130-1338"
ENSGALG00000004545	0.074409221	0.489180374	-2.564088703	2.35E-06	7.16E-06	down	yes	0	0.083037404	0.140190258	0.420675163	0.419918051	0.626947907	10	8767591	8861883	+	WDR72	protein_coding	GO:0070166|enamel mineralization	GO:0005737|cytoplasm; GO:0005768|endosome	--	--	--	3722	XP_004943847.3	XP_004943847.3 WD repeat-containing protein 72 isoform X1 [Gallus gallus]	sp|Q3MJ13|WDR72_HUMAN	sp|Q3MJ13|WDR72_HUMAN WD repeat-containing protein 72 OS=Homo sapiens GN=WDR72 PE=2 SV=2	9031.ENSGALP00000007225	WD repeat domain 72	_	KOG4155	_	"PF00400.29|WD40|WD domain, G-beta repeat|ENSGALT00000007237|m.5477:440-480"
ENSGALG00000004562	3.4824984	1.702563503	1.028101969	5.67E-16	4.07E-15	up	yes	3.952669113	3.254222937	3.240603151	1.700987788	1.589762224	1.816940498	15	6282908	6293393	-	HVCN1	protein_coding	GO:0009268|response to pH; GO:0010043|response to zinc ion; GO:0071294|cellular response to zinc ion; GO:0071467|cellular response to pH; GO:1902600|proton transmembrane transport	GO:0005887|integral component of plasma membrane; GO:0016021|integral component of membrane	GO:0030171|voltage-gated proton channel activity	--	--	5951	XP_015130783.1	XP_015130783.1 voltage-gated hydrogen channel 1 isoform X1 [Gallus gallus]	sp|Q5F4C0|HVCN1_CHICK	sp|Q5F4C0|HVCN1_CHICK Voltage-gated hydrogen channel 1 OS=Gallus gallus GN=HVCN1 PE=2 SV=1	9031.ENSGALP00000007248	Voltage-gated hydrogen channel 1 (Hydrogen voltage-gated channel 1)(HV1); Mediates the volta [...] 	_	_	NOG46709	"PF16799.2|VGPC1_C|C-terminal membrane-localisation domain of ion-channel, VCN1|ENSGALT00000007260|m.10567:188-235;PF00520.28|Ion_trans|Ion transport protein|ENSGALT00000007260|m.10567:62-177"
ENSGALG00000004591	2.304483249	0.900867853	1.345376451	5.09E-07	1.68E-06	up	yes	2.547762544	1.806438577	2.559248625	1.032054439	0.94119358	0.729355538	8	7765201	7771303	+	SERPINC1	protein_coding	"GO:0007596|blood coagulation; GO:2000266|regulation of blood coagulation, intrinsic pathway"	GO:0005615|extracellular space	GO:0004867|serine-type endopeptidase inhibitor activity; GO:0008201|heparin binding	"ko:K03911|SERPINC1,AT3"	ko04610|Complement and coagulation cascades	1882	NP_001340874.1	NP_001340874.1 antithrombin-III precursor [Gallus gallus]	sp|P32262|ANT3_SHEEP	sp|P32262|ANT3_SHEEP Antithrombin-III OS=Ovis aries GN=SERPINC1 PE=2 SV=1	_	_	_	_	_	PF00079.17|Serpin|Serpin (serine protease inhibitor)|ENSGALT00000007304|m.7273:135-511
ENSGALG00000004593	6.560445556	13.50234249	-1.04021469	3.69E-17	2.87E-16	down	yes	7.294761764	5.834755267	6.551819637	12.44964769	15.66511497	12.39226481	20	5918672	5975454	-	SULF2	protein_coding	GO:0001822|kidney development; GO:0002063|chondrocyte development; GO:0003094|glomerular filtration; GO:0009611|response to wounding; GO:0010575|positive regulation of vascular endothelial growth factor production; GO:0014846|esophagus smooth muscle contraction; GO:0030177|positive regulation of Wnt signaling pathway; GO:0030201|heparan sulfate proteoglycan metabolic process; GO:0032836|glomerular basement membrane development; GO:0035860|glial cell-derived neurotrophic factor receptor signaling pathway; GO:0040037|negative regulation of fibroblast growth factor receptor signaling pathway; GO:0048706|embryonic skeletal system development; GO:0051216|cartilage development; GO:0060348|bone development; GO:0060384|innervation; GO:0090263|positive regulation of canonical Wnt signaling pathway; GO:0097421|liver regeneration; GO:2000345|regulation of hepatocyte proliferation	GO:0005615|extracellular space; GO:0005783|endoplasmic reticulum; GO:0005795|Golgi stack; GO:0005886|plasma membrane; GO:0009986|cell surface	GO:0004065|arylsulfatase activity; GO:0005509|calcium ion binding; GO:0008449|N-acetylglucosamine-6-sulfatase activity	ko:K14607|SULF	--	2622	XP_417386.2	XP_417386.2 extracellular sulfatase Sulf-2 isoform X1 [Gallus gallus]	sp|Q8IWU5|SULF2_HUMAN	sp|Q8IWU5|SULF2_HUMAN Extracellular sulfatase Sulf-2 OS=Homo sapiens GN=SULF2 PE=1 SV=1	9031.ENSGALP00000007297	sulfatase 2	COG3119	KOG3731	_	PF12548.5|DUF3740|Sulfatase protein|ENSGALT00000007309|m.3077:526-667;PF00884.20|Sulfatase|Sulfatase|ENSGALT00000007309|m.3077:44-374
ENSGALG00000004611	11.9858953	3.894405171	1.619366157	2.01E-50	7.32E-49	up	yes	12.2705276	11.31599586	12.37116245	3.944766682	3.946169453	3.792279378	14	4550654	4569107	-	FBXL18	protein_coding	GO:0000209|protein polyubiquitination; GO:0031146|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0043687|post-translational protein modification	GO:0005829|cytosol	GO:0004842|ubiquitin-protein transferase activity	ko:K10284|FBXL18	--	2482	NP_001012804.1	NP_001012804.1 F-box/LRR-repeat protein 18 [Gallus gallus]	sp|Q96ME1|FXL18_HUMAN	sp|Q96ME1|FXL18_HUMAN F-box/LRR-repeat protein 18 OS=Homo sapiens GN=FBXL18 PE=1 SV=2	9031.ENSGALP00000007325	F-box and leucine-rich repeat protein 18 	_	_	NOG72426	PF00646.30|F-box|F-box domain|ENSGALT00000007337|m.9342:42-82;PF12937.4|F-box-like|F-box-like|ENSGALT00000007337|m.9342:45-86
ENSGALG00000004618	97.17340022	36.84238868	1.398951776	1.95E-121	4.62E-119	up	yes	97.92973688	96.83901213	96.75145164	36.69374197	36.72753302	37.10589106	19	6788637	6792217	+	TAX1BP3	protein_coding	GO:0007266|Rho protein signal transduction; GO:0008285|negative regulation of cell population proliferation; GO:0016055|Wnt signaling pathway; GO:0030178|negative regulation of Wnt signaling pathway; GO:0090630|activation of GTPase activity; GO:2000009|negative regulation of protein localization to cell surface	GO:0001650|fibrillar center; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0015629|actin cytoskeleton; GO:0043231|intracellular membrane-bounded organelle; GO:0070062|extracellular exosome	GO:0008013|beta-catenin binding; GO:0008022|protein C-terminus binding	--	--	1810	XP_415850.1	XP_415850.1 tax1-binding protein 3 [Gallus gallus]	sp|O14907|TX1B3_HUMAN	sp|O14907|TX1B3_HUMAN Tax1-binding protein 3 OS=Homo sapiens GN=TAX1BP3 PE=1 SV=2	_	_	_	_	_	PF00595.21|PDZ|PDZ domain (Also known as DHR or GLGF)|ENSGALT00000007351|m.14052:46-129;PF13180.3|PDZ_2|PDZ domain|ENSGALT00000007351|m.14052:67-138
ENSGALG00000004621	16.61913286	34.02126158	-1.033147695	3.03E-53	1.22E-51	down	yes	16.61311881	17.60516917	15.63911059	33.18036686	34.90715351	33.97626436	20	6185927	6338401	-	PREX1	protein_coding	GO:0006469|negative regulation of protein kinase activity; GO:0006801|superoxide metabolic process; GO:0007186|G protein-coupled receptor signaling pathway; GO:0030041|actin filament polymerization; GO:0030217|T cell differentiation; GO:0030335|positive regulation of cell migration; GO:0030593|neutrophil chemotaxis; GO:0030833|regulation of actin filament polymerization; GO:0032007|negative regulation of TOR signaling; GO:0035023|regulation of Rho protein signal transduction; GO:0035556|intracellular signal transduction; GO:0042119|neutrophil activation; GO:0043065|positive regulation of apoptotic process; GO:0050773|regulation of dendrite development; GO:0051056|regulation of small GTPase mediated signal transduction; GO:1900026|positive regulation of substrate adhesion-dependent cell spreading	GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0030426|growth cone; GO:0043198|dendritic shaft; GO:0048471|perinuclear region of cytoplasm	GO:0005085|guanyl-nucleotide exchange factor activity; GO:0005089|Rho guanyl-nucleotide exchange factor activity; GO:0005096|GTPase activator activity; GO:0005543|phospholipid binding; GO:0019899|enzyme binding; GO:0030676|Rac guanyl-nucleotide exchange factor activity	ko:K12365|PREX1	ko04062|Chemokine signaling pathway	5043	XP_015152178.1	"XP_015152178.1 phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein isoform X2 [Gallus gallus]"	sp|Q8TCU6|PREX1_HUMAN	"sp|Q8TCU6|PREX1_HUMAN Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein OS=Homo sapiens GN=PREX1 PE=1 SV=3"	9031.ENSGALP00000007346	"phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1"	COG5422	KOG2378;KOG3519;KOG4428	_	"PF00621.17|RhoGEF|RhoGEF domain|ENSGALT00000093591|m.3079:35-220;PF00610.18|DEP|Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)|ENSGALT00000093591|m.3079:409-475;PF00610.18|DEP|Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)|ENSGALT00000093591|m.3079:510-576"
ENSGALG00000004637	4.70394362	9.735631437	-1.04782116	1.74E-12	9.50E-12	down	yes	4.571233872	4.781662574	4.758934413	11.30259254	9.352901867	8.551399908	19	6800175	6808318	+	ENSGALG00000004637	protein_coding	"GO:0005975|carbohydrate metabolic process; GO:0009052|pentose-phosphate shunt, non-oxidative branch; GO:0016310|phosphorylation; GO:0035963|cellular response to interleukin-13; GO:0043030|regulation of macrophage activation; GO:0050727|regulation of inflammatory response; GO:0071222|cellular response to lipopolysaccharide; GO:0071353|cellular response to interleukin-4"	GO:0005737|cytoplasm	GO:0005524|ATP binding; GO:0050277|sedoheptulokinase activity	ko:K11214|SHPK	ko00710|Carbon fixation in photosynthetic organisms	1729	XP_415852.4	XP_415852.4 sedoheptulokinase isoform X1 [Gallus gallus]	sp|Q9D5J6|SHPK_MOUSE	sp|Q9D5J6|SHPK_MOUSE Sedoheptulokinase OS=Mus musculus GN=Shpk PE=1 SV=1	9031.ENSGALP00000007376	carbohydrate kinase-like	COG1070	KOG2517	_	"PF00370.18|FGGY_N|FGGY family of carbohydrate kinases, N-terminal domain|ENSGALT00000007388|m.14055:10-100;PF00370.18|FGGY_N|FGGY family of carbohydrate kinases, N-terminal domain|ENSGALT00000007388|m.14055:142-261"
ENSGALG00000004655	43.93262394	104.8548788	-1.254838649	6.30E-71	4.23E-69	down	yes	42.41667384	45.45376153	43.92743644	98.94161138	114.0889916	101.5340334	14	4669726	4684664	-	SMURF1	protein_coding	"GO:0000209|protein polyubiquitination; GO:0006511|ubiquitin-dependent protein catabolic process; GO:0006611|protein export from nucleus; GO:0007179|transforming growth factor beta receptor signaling pathway; GO:0007398|ectoderm development; GO:0016567|protein ubiquitination; GO:0030154|cell differentiation; GO:0030279|negative regulation of ossification; GO:0030509|BMP signaling pathway; GO:0030512|negative regulation of transforming growth factor beta receptor signaling pathway; GO:0030514|negative regulation of BMP signaling pathway; GO:0030579|ubiquitin-dependent SMAD protein catabolic process; GO:0032801|receptor catabolic process; GO:0034394|protein localization to cell surface; GO:0043161|proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0060071|Wnt signaling pathway, planar cell polarity pathway; GO:0061734|parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization; GO:0061736|engulfment of target by autophagosome; GO:0061753|substrate localization to autophagosome; GO:0071211|protein targeting to vacuole involved in autophagy; GO:0072659|protein localization to plasma membrane; GO:1903861|positive regulation of dendrite extension; GO:2000060|positive regulation of ubiquitin-dependent protein catabolic process"	GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0030424|axon; GO:0043025|neuronal cell body; GO:0070062|extracellular exosome	GO:0004842|ubiquitin-protein transferase activity; GO:0005543|phospholipid binding; GO:0048185|activin binding; GO:0061630|ubiquitin protein ligase activity; GO:0070411|I-SMAD binding; GO:0070412|R-SMAD binding	ko:K04678|SMURF	ko04120|Ubiquitin mediated proteolysis; ko04144|Endocytosis; ko04340|Hedgehog signaling pathway; ko04341|Hedgehog signaling pathway - fly; ko04350|TGF-beta signaling pathway	2235	EOB00968.1	"EOB00968.1 E3 ubiquitin-protein ligase SMURF1, partial [Anas platyrhynchos]"	sp|Q9HCE7|SMUF1_HUMAN	sp|Q9HCE7|SMUF1_HUMAN E3 ubiquitin-protein ligase SMURF1 OS=Homo sapiens GN=SMURF1 PE=1 SV=2	59729.ENSTGUP00000007875	E3 ubiquitin-protein ligase SMURF1 (hSMURF1)(EC 6.3.2.-)(SMAD ubiquitination regulatory fact [...] 	COG5021	KOG0940	_	PF00632.22|HECT|HECT-domain (ubiquitin-transferase)|ENSGALT00000007417|m.9356:436-743;PF00397.23|WW|WW domain|ENSGALT00000007417|m.9356:237-266;PF00397.23|WW|WW domain|ENSGALT00000007417|m.9356:293-322;PF00168.27|C2|C2 domain|ENSGALT00000007417|m.9356:17-104
ENSGALG00000004661	65.56619208	28.11869675	1.221129417	5.28E-30	8.29E-29	up	yes	68.87478076	62.45692954	65.36686595	27.88908977	28.03359579	28.43340469	12	3654065	3659153	-	SHISA5	protein_coding	GO:0006915|apoptotic process	GO:0005789|endoplasmic reticulum membrane; GO:0016021|integral component of membrane; GO:0031965|nuclear membrane	--	ko:K10135|SCOTIN	ko04115|p53 signaling pathway	420	NP_001025762.1	NP_001025762.1 protein shisa-5 [Gallus gallus]	sp|Q5ZIS9|SHSA5_CHICK	sp|Q5ZIS9|SHSA5_CHICK Protein shisa-5 OS=Gallus gallus GN=Shisa5 PE=2 SV=1	9031.ENSGALP00000007414	Protein shisa-5 (Scotin); Can induce apoptosis in a caspase-depenent manner and plays a role [...] 	_	_	NOG42686	PF13908.3|Shisa|Wnt and FGF inhibitory regulator|ENSGALT00000071108|m.7408:3-94
ENSGALG00000004662	1.11464614	3.378570907	-1.591205819	6.60E-21	6.49E-20	down	yes	1.219883318	1.13485486	0.989200243	3.207064353	3.83373647	3.094911896	21	5722669	5738134	-	DISP3	protein_coding	GO:0008203|cholesterol metabolic process; GO:0009725|response to hormone; GO:0042632|cholesterol homeostasis; GO:0045665|negative regulation of neuron differentiation; GO:0045834|positive regulation of lipid metabolic process; GO:2000179|positive regulation of neural precursor cell proliferation	GO:0005783|endoplasmic reticulum; GO:0005789|endoplasmic reticulum membrane; GO:0016021|integral component of membrane; GO:0030659|cytoplasmic vesicle membrane; GO:0031965|nuclear membrane	--	--	--	4017	XP_015152406.1	XP_015152406.1 protein dispatched homolog 3 isoform X1 [Gallus gallus]	sp|B9U3F2|DISP3_CHICK	sp|B9U3F2|DISP3_CHICK Protein dispatched homolog 3 OS=Gallus gallus GN=DISP3 PE=1 SV=1	9031.ENSGALP00000007415	Disp3 	_	KOG3664	_	PF02460.15|Patched|Patched family|ENSGALT00000007427|m.4293:356-641;PF03176.12|MMPL|MMPL family|ENSGALT00000007427|m.4293:377-558;PF03176.12|MMPL|MMPL family|ENSGALT00000007427|m.4293:1131-1293;PF12349.5|Sterol-sensing|Sterol-sensing domain of SREBP cleavage-activation|ENSGALT00000007427|m.4293:429-557
ENSGALG00000004675	8.60007977	3.585416616	1.259867652	6.48E-36	1.34E-34	up	yes	9.093641994	7.939190008	8.767407306	3.439197598	3.670000172	3.647052079	11	9900952	9905204	+	RGS9BP	protein_coding	GO:0009968|negative regulation of signal transduction; GO:0050908|detection of light stimulus involved in visual perception	GO:0001750|photoreceptor outer segment; GO:0016021|integral component of membrane	--	--	--	4253	NP_989836.1	NP_989836.1 regulator of G-protein signaling 9-binding protein [Gallus gallus]	sp|Q6XK22|R9BP_CHICK	sp|Q6XK22|R9BP_CHICK Regulator of G-protein signaling 9-binding protein OS=Gallus gallus GN=RGS9BP PE=2 SV=1	9031.ENSGALP00000007438	Regulator of G-protein signaling 9-binding protein (RGS9-anchor protein); Regulator of G pro [...] 	_	_	NOG40375	_
ENSGALG00000004676	3.551605619	1.451922936	1.284660511	9.33E-07	2.99E-06	up	yes	2.927282728	3.661311819	4.066222312	1.21443981	1.379060282	1.762268716	12	3703348	3704648	+	ENSGALG00000004676	protein_coding	GO:0008285|negative regulation of cell population proliferation; GO:0045603|positive regulation of endothelial cell differentiation; GO:0045663|positive regulation of myoblast differentiation; GO:0045766|positive regulation of angiogenesis; GO:2000271|positive regulation of fibroblast apoptotic process	GO:0005634|nucleus; GO:0005737|cytoplasm	GO:0019899|enzyme binding	--	--	1165	XP_015148972.1	XP_015148972.1 protein BTG1 [Gallus gallus]	sp|P34743|BTG1_CHICK	sp|P34743|BTG1_CHICK Protein BTG1 OS=Gallus gallus GN=BTG1 PE=2 SV=1	9031.ENSGALP00000007439	hypothetical LOC415950	_	KOG4006	_	PF07742.9|BTG|BTG family|ENSGALT00000007451|m.7424:15-127
ENSGALG00000004749	21.60836615	10.34095183	1.062494054	4.87E-21	4.83E-20	up	yes	20.01765081	22.47030287	22.33714477	11.37218978	9.568989714	10.081676	14	4924362	4932502	+	TMEM11	protein_coding	GO:0007005|mitochondrion organization	GO:0031305|integral component of mitochondrial inner membrane	--	--	--	1274	NP_001026637.1	"NP_001026637.1 transmembrane protein 11, mitochondrial [Gallus gallus]"	sp|Q5ZLD4|TMM11_CHICK	"sp|Q5ZLD4|TMM11_CHICK Transmembrane protein 11, mitochondrial OS=Gallus gallus GN=TMEM11 PE=2 SV=1"	10141.ENSCPOP00000007629	transmembrane protein 11	_	_	NOG73433	PF14972.3|Mito_morph_reg|Mitochondrial morphogenesis regulator|ENSGALT00000007570|m.9381:131-293
ENSGALG00000004756	6.672534571	16.22389187	-1.280541608	1.09E-29	1.68E-28	down	yes	6.470835504	6.89070845	6.656059758	14.66191052	18.47144551	15.53831956	11	9962507	9982421	-	CEP89	protein_coding	GO:0007005|mitochondrion organization; GO:0007268|chemical synaptic transmission; GO:0060271|cilium assembly; GO:0097711|ciliary basal body-plasma membrane docking; GO:1905515|non-motile cilium assembly	GO:0000922|spindle pole; GO:0005758|mitochondrial intermembrane space; GO:0005813|centrosome; GO:0005814|centriole; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0031514|motile cilium; GO:0097539|ciliary transition fiber; GO:0097730|non-motile cilium	--	ko:K16543|CEP89	--	2394	XP_021264086.1	XP_021264086.1 centrosomal protein of 89 kDa isoform X2 [Numida meleagris]	sp|Q96ST8|CEP89_HUMAN	sp|Q96ST8|CEP89_HUMAN Centrosomal protein of 89 kDa OS=Homo sapiens GN=CEP89 PE=1 SV=3	9031.ENSGALP00000007576	coiled-coil domain containing 123	_	_	NOG75458	_
ENSGALG00000004760	0.509841976	1.301193324	-1.334735377	4.00E-05	0.000104033	down	yes	0.653677667	0.342340738	0.533507522	1.238179768	1.440365428	1.225034777	15	6543749	6557011	-	TMEM116	protein_coding	--	GO:0016021|integral component of membrane	--	--	--	2064	XP_015131033.1	XP_015131033.1 transmembrane protein 116 isoform X2 [Gallus gallus]	sp|A2BGS3|TM116_DANRE	sp|A2BGS3|TM116_DANRE Transmembrane protein 116 OS=Danio rerio GN=tmem116 PE=2 SV=1	_	_	_	_	_	_
ENSGALG00000004781	1.165484986	5.939545654	-2.339523387	2.32E-34	4.52E-33	down	yes	0.869977484	1.588652992	1.037824483	5.050616823	6.738635581	6.02938456	21	6175387	6201927	-	ZBTB40	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated; GO:0006974|cellular response to DNA damage stimulus; GO:0030282|bone mineralization"	GO:0005634|nucleus	GO:0003677|DNA binding; GO:0046872|metal ion binding	ko:K10512|ZBTB40	--	3210	XP_024998352.1	XP_024998352.1 zinc finger and BTB domain-containing protein 40 isoform X4 [Gallus gallus]	sp|Q9NUA8|ZBT40_HUMAN	sp|Q9NUA8|ZBT40_HUMAN Zinc finger and BTB domain-containing protein 40 OS=Homo sapiens GN=ZBTB40 PE=1 SV=4	9031.ENSGALP00000007623	zinc finger and BTB domain containing 40	COG5048	KOG1721	_	"PF00096.23|zf-C2H2|Zinc finger, C2H2 type|ENSGALT00000039248|m.4308:809-831;PF00651.28|BTB|BTB/POZ domain|ENSGALT00000039248|m.4308:18-114"
ENSGALG00000004812	5.772164719	13.49305449	-1.223604179	1.41E-05	3.90E-05	down	yes	3.654873233	6.172371846	7.489249078	12.76248479	13.30331714	14.41336153	8	8332878	8393131	-	FAM129A	protein_coding	GO:0001933|negative regulation of protein phosphorylation; GO:0001934|positive regulation of protein phosphorylation; GO:0034976|response to endoplasmic reticulum stress; GO:0045727|positive regulation of translation	GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0016020|membrane; GO:0070062|extracellular exosome	--	--	--	4173	XP_015145793.1	XP_015145793.1 protein Niban isoform X1 [Gallus gallus]	sp|Q9BZQ8|NIBAN_HUMAN	sp|Q9BZQ8|NIBAN_HUMAN Protein Niban OS=Homo sapiens GN=FAM129A PE=1 SV=1	9031.ENSGALP00000007671	hypothetical protein LOC424451 	_	_	NOG46977	_
ENSGALG00000004820	9.283273883	3.89654923	1.250292131	0.00036449	0.000822298	up	yes	10.62677427	8.116208465	9.10683891	3.331034908	4.815766065	3.542846717	19	7085977	7086290	-	ENSGALG00000004820	protein_coding	--	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	--	--	--	238	XP_015151606.1	XP_015151606.1 protein FAM57A isoform X1 [Gallus gallus]	sp|Q5ND56|FA57A_MOUSE	sp|Q5ND56|FA57A_MOUSE Protein FAM57A OS=Mus musculus GN=Fam57a PE=3 SV=1	59729.ENSTGUP00000007487	Protein FAM57A (CT120 protein) [Taeniopygia guttata]	_	KOG4561	_	_
ENSGALG00000004832	1.063797653	2.305921347	-1.108864101	3.16E-05	8.35E-05	down	yes	0.697235584	1.223261438	1.270895936	2.566439608	1.969672321	2.381652111	4	1893812	1898775	-	RBM41	protein_coding	"GO:0000398|mRNA splicing, via spliceosome; GO:0032502|developmental process"	GO:0005689|U12-type spliceosomal complex	GO:0030626|U12 snRNA binding; GO:0097157|pre-mRNA intronic binding	--	--	2116	XP_426256.3	XP_426256.3 RNA-binding protein 41 isoform X1 [Gallus gallus]	sp|Q96IZ5|RBM41_HUMAN	sp|Q96IZ5|RBM41_HUMAN RNA-binding protein 41 OS=Homo sapiens GN=RBM41 PE=1 SV=2	9031.ENSGALP00000007706	RNA binding motif protein 41	_	KOG4206	_	"PF00076.19|RRM_1|RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)|ENSGALT00000007718|m.16079:300-368"
ENSGALG00000004833	45.3432372	19.73160622	1.199966155	4.46E-62	2.34E-60	up	yes	47.19940994	43.90130943	44.92899225	20.056256	18.93509849	20.20346415	21	6377332	6383361	+	P3H1	protein_coding	GO:0032963|collagen metabolic process; GO:0050708|regulation of protein secretion; GO:0050821|protein stabilization; GO:0060348|bone development; GO:0061077|chaperone-mediated protein folding; GO:1901874|negative regulation of post-translational protein modification	GO:0005783|endoplasmic reticulum; GO:0016020|membrane; GO:0032991|protein-containing complex; GO:0070062|extracellular exosome	GO:0005506|iron ion binding; GO:0019797|procollagen-proline 3-dioxygenase activity; GO:0031418|L-ascorbic acid binding; GO:0044877|protein-containing complex binding	ko:K08134|LEPRE	--	2178	NP_001001529.1	NP_001001529.1 prolyl 3-hydroxylase 1 precursor [Gallus gallus]	sp|Q6JHU8|P3H1_CHICK	sp|Q6JHU8|P3H1_CHICK Prolyl 3-hydroxylase 1 OS=Gallus gallus GN=P3H1 PE=1 SV=1	9031.ENSGALP00000007707	leucine proline-enriched proteoglycan (leprecan) 1 (EC:1.14.11.7); Has prolyl 3-hydroxylase  [...] 	_	KOG4459	_	PF13640.3|2OG-FeII_Oxy_3|2OG-Fe(II) oxygenase superfamily|ENSGALT00000007719|m.4318:577-669;PF03171.17|2OG-FeII_Oxy|2OG-Fe(II) oxygenase superfamily|ENSGALT00000007719|m.4318:595-670
ENSGALG00000004860	35.27034962	75.99784543	-1.107283482	9.28E-33	1.69E-31	down	yes	41.04716144	31.59041468	33.17347273	79.09274891	70.76266024	78.13812714	14	5183631	5185545	-	RASD1	protein_coding	"GO:0007263|nitric oxide mediated signal transduction; GO:0045892|negative regulation of transcription, DNA-templated"	GO:0005634|nucleus; GO:0005886|plasma membrane; GO:0016529|sarcoplasmic reticulum; GO:0048471|perinuclear region of cytoplasm	GO:0003924|GTPase activity; GO:0005525|GTP binding	ko:K07843|RASD1	ko04713|Circadian entrainment	1706	NP_001038101.1	NP_001038101.1 dexamethasone-induced Ras-related protein 1 [Gallus gallus]	sp|O35626|RASD1_MOUSE	sp|O35626|RASD1_MOUSE Dexamethasone-induced Ras-related protein 1 OS=Mus musculus GN=Rasd1 PE=1 SV=1	9031.ENSGALP00000007751	"RAS, dexamethasone-induced 1 "	COG1100	KOG0395	_	"PF00071.19|Ras|Ras family|ENSGALT00000007764|m.9398:78-244;PF08477.10|Roc|Ras of Complex, Roc, domain of DAPkinase|ENSGALT00000007764|m.9398:78-200;PF00025.18|Arf|ADP-ribosylation factor family|ENSGALT00000007764|m.9398:75-238"
ENSGALG00000004917	2.945622899	9.095967031	-1.623350025	6.50E-35	1.29E-33	down	yes	3.184518919	2.750302277	2.9020475	9.626900849	8.136302266	9.524697979	19	7178655	7196511	+	DOC2B	protein_coding	GO:0006906|vesicle fusion; GO:0008104|protein localization; GO:0017158|regulation of calcium ion-dependent exocytosis; GO:0031340|positive regulation of vesicle fusion; GO:0032024|positive regulation of insulin secretion; GO:0045956|positive regulation of calcium ion-dependent exocytosis; GO:0048791|calcium ion-regulated exocytosis of neurotransmitter	GO:0005737|cytoplasm; GO:0005886|plasma membrane; GO:0070382|exocytic vesicle; GO:0098793|presynapse	GO:0005509|calcium ion binding; GO:0005544|calcium-dependent phospholipid binding; GO:0019905|syntaxin binding; GO:0030276|clathrin binding	ko:K19917|DOC2B	--	2697	XP_415868.2	XP_415868.2 double C2-like domain-containing protein beta isoform X2 [Gallus gallus]	sp|Q14184|DOC2B_HUMAN	sp|Q14184|DOC2B_HUMAN Double C2-like domain-containing protein beta OS=Homo sapiens GN=DOC2B PE=1 SV=1	13616.ENSMODP00000012714	"double C2-like domains, beta"	_	KOG1013	_	PF00168.27|C2|C2 domain|ENSGALT00000007864|m.14087:128-231;PF00168.27|C2|C2 domain|ENSGALT00000007864|m.14087:269-372
ENSGALG00000004969	3.451976736	15.28392341	-2.143290619	1.53E-96	1.76E-94	down	yes	3.364765014	3.824961953	3.166203243	16.10247479	14.3754793	15.37381614	12	5131077	5237794	-	TIMP4	protein_coding	GO:0007219|Notch signaling pathway; GO:0007417|central nervous system development; GO:0009725|response to hormone; GO:0032496|response to lipopolysaccharide; GO:0034097|response to cytokine; GO:0042493|response to drug; GO:0042698|ovulation cycle; GO:0043086|negative regulation of catalytic activity; GO:0043434|response to peptide hormone; GO:0051045|negative regulation of membrane protein ectodomain proteolysis	GO:0005615|extracellular space; GO:0030017|sarcomere; GO:0031012|extracellular matrix	GO:0002020|protease binding; GO:0008191|metalloendopeptidase inhibitor activity; GO:0046872|metal ion binding	--	--	3250	XP_001232059.1	XP_001232059.1 metalloproteinase inhibitor 4 isoform X1 [Gallus gallus]	sp|Q99727|TIMP4_HUMAN	sp|Q99727|TIMP4_HUMAN Metalloproteinase inhibitor 4 OS=Homo sapiens GN=TIMP4 PE=2 SV=1	_	_	_	_	_	PF00965.14|TIMP|Tissue inhibitor of metalloproteinase|ENSGALT00000046299|m.7456:25-204
ENSGALG00000004974	7.700052958	24.29933211	-1.656697582	1.45E-45	4.53E-44	down	yes	7.419957289	6.593804514	9.086397072	25.67546566	21.60992106	25.61260961	12	5238244	5289513	+	PPARG	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006351|transcription, DNA-templated; GO:0006919|activation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0008217|regulation of blood pressure; GO:0010629|negative regulation of gene expression; GO:0010742|macrophage derived foam cell differentiation; GO:0010745|negative regulation of macrophage derived foam cell differentiation; GO:0010871|negative regulation of receptor biosynthetic process; GO:0010875|positive regulation of cholesterol efflux; GO:0010887|negative regulation of cholesterol storage; GO:0010891|negative regulation of sequestering of triglyceride; GO:0030224|monocyte differentiation; GO:0031394|positive regulation of prostaglandin biosynthetic process; GO:0032385|positive regulation of intracellular cholesterol transport; GO:0032526|response to retinoic acid; GO:0032869|cellular response to insulin stimulus; GO:0035357|peroxisome proliferator activated receptor signaling pathway; GO:0042593|glucose homeostasis; GO:0042752|regulation of circadian rhythm; GO:0042953|lipoprotein transport; GO:0043388|positive regulation of DNA binding; GO:0045600|positive regulation of fat cell differentiation; GO:0045713|low-density lipoprotein particle receptor biosynthetic process; GO:0045893|positive regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0048469|cell maturation; GO:0048511|rhythmic process; GO:0048662|negative regulation of smooth muscle cell proliferation; GO:0050714|positive regulation of protein secretion; GO:0050872|white fat cell differentiation; GO:0051091|positive regulation of DNA-binding transcription factor activity; GO:0060336|negative regulation of interferon-gamma-mediated signaling pathway; GO:0060850|regulation of transcription involved in cell fate commitment; GO:0071404|cellular response to low-density lipoprotein particle stimulus; GO:1903076|regulation of protein localization to plasma membrane"	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0090575|RNA polymerase II transcription factor complex	GO:0001046|core promoter sequence-specific DNA binding; GO:0003677|DNA binding; GO:0003682|chromatin binding; GO:0003700|DNA-binding transcription factor activity; GO:0003707|steroid hormone receptor activity; GO:0004879|nuclear receptor activity; GO:0008022|protein C-terminus binding; GO:0008144|drug binding; GO:0008270|zinc ion binding; GO:0019899|enzyme binding; GO:0030374|nuclear receptor transcription coactivator activity; GO:0033613|activating transcription factor binding; GO:0042277|peptide binding; GO:0042802|identical protein binding; GO:0043621|protein self-association; GO:0044212|transcription regulatory region DNA binding; GO:0046965|retinoid X receptor binding; GO:0046982|protein heterodimerization activity; GO:0050692|DBD domain binding; GO:0050693|LBD domain binding; GO:0051393|alpha-actinin binding	"ko:K08530|NR1C3,PPARG"	ko03320|PPAR signaling pathway; ko04152|AMPK signaling pathway; ko04211|Longevity regulating pathway; ko04380|Osteoclast differentiation; ko05016|Huntington's disease; ko05200|Pathways in cancer; ko05202|Transcriptional misregulation in cancer; ko05216|Thyroid cancer	2090	XP_003210088.2	XP_003210088.2 PREDICTED: peroxisome proliferator-activated receptor gamma isoform X1 [Meleagris gallopavo]	sp|O62807|PPARG_PIG	sp|O62807|PPARG_PIG Peroxisome proliferator-activated receptor gamma OS=Sus scrofa GN=PPARG PE=2 SV=1	9031.ENSGALP00000007962	peroxisome proliferative activated receptor gamma 	_	KOG3575	_	"PF12577.5|PPARgamma_N|PPAR gamma N-terminal region|ENSGALT00000007976|m.7467:3-80;PF00105.15|zf-C4|Zinc finger, C4 type (two domains)|ENSGALT00000007976|m.7467:110-176;PF00104.27|Hormone_recep|Ligand-binding domain of nuclear hormone receptor|ENSGALT00000007976|m.7467:290-457"
ENSGALG00000005014	0.490131151	0.144539221	1.694333435	0.000305492	0.000696333	up	yes	0.743833497	0.291714545	0.434845412	0.175683112	0.116305077	0.141629475	4	2050685	2055056	+	ENSGALG00000005014	protein_coding	"GO:0001895|retina homeostasis; GO:0007601|visual perception; GO:0007603|phototransduction, visible light; GO:0018343|protein farnesylation; GO:0043066|negative regulation of apoptotic process"	GO:0001917|photoreceptor inner segment; GO:0005634|nucleus; GO:0005737|cytoplasm	GO:0001918|farnesylated protein binding; GO:0051082|unfolded protein binding	"ko:K17767|AIP,XAP2"	--	3046	OXB57177.1	OXB57177.1 hypothetical protein ASZ78_000578 [Callipepla squamata]	sp|Q9NZN9|AIPL1_HUMAN	sp|Q9NZN9|AIPL1_HUMAN Aryl-hydrocarbon-interacting protein-like 1 OS=Homo sapiens GN=AIPL1 PE=1 SV=2	_	_	_	_	_	PF00254.25|FKBP_C|FKBP-type peptidyl-prolyl cis-trans isomerase|ENSGALT00000008029|m.16106:27-89
ENSGALG00000005016	1.260390136	4.150519715	-1.711492139	1.92E-38	4.50E-37	down	yes	1.187728604	1.229013207	1.364428597	3.937990523	4.428457854	4.085110767	Z	79844243	79926708	+	ZNF608	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006351|transcription, DNA-templated; GO:0033085|negative regulation of T cell differentiation in thymus"	--	GO:0003676|nucleic acid binding; GO:0046872|metal ion binding	--	--	5501	XP_004949752.1	XP_004949752.1 zinc finger protein 608 isoform X2 [Gallus gallus]	sp|Q56A10|ZN608_MOUSE	sp|Q56A10|ZN608_MOUSE Zinc finger protein 608 OS=Mus musculus GN=Znf608 PE=1 SV=1	59729.ENSTGUP00000001133	Zinc finger protein 608 (Renal carcinoma antigen NY-REN-36) [Taeniopygia guttata]	_	_	NOG86608	_
ENSGALG00000005024	5.760702441	13.52813372	-1.230210025	3.58E-26	4.73E-25	down	yes	5.406369057	5.730276178	6.145462089	13.39223017	13.13940028	14.05277073	12	5546824	5591184	-	ENSGALG00000005024	protein_coding	--	--	GO:0005509|calcium ion binding	--	--	1881	XP_004944581.1	XP_004944581.1 EF-hand and coiled-coil domain-containing protein 1 isoform X1 [Gallus gallus]	sp|Q9HA90|EFCC1_HUMAN	sp|Q9HA90|EFCC1_HUMAN EF-hand and coiled-coil domain-containing protein 1 OS=Homo sapiens GN=EFCC1 PE=2 SV=2	13616.ENSMODP00000010463	annotation not avaliable	_	_	NOG45785	PF15799.2|CCD48|Coiled-coil domain-containing protein 48|ENSGALT00000036273|m.7493:8-237;PF15799.2|CCD48|Coiled-coil domain-containing protein 48|ENSGALT00000036273|m.7493:250-626
ENSGALG00000005030	2.889434266	7.113757856	-1.296867048	1.01E-36	2.22E-35	down	yes	2.618377696	3.155528076	2.894397027	6.605609179	7.757763835	6.977900555	9	8661263	8781136	-	DOCK10	protein_coding	GO:0001782|B cell homeostasis; GO:0002315|marginal zone B cell differentiation; GO:0007264|small GTPase mediated signal transduction; GO:0030334|regulation of cell migration; GO:0043547|positive regulation of GTPase activity; GO:0060997|dendritic spine morphogenesis	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0016020|membrane; GO:0043197|dendritic spine; GO:0070062|extracellular exosome	GO:0005085|guanyl-nucleotide exchange factor activity	--	--	6639	XP_015132496.1	XP_015132496.1 dedicator of cytokinesis protein 10 isoform X4 [Gallus gallus]	sp|Q96BY6|DOC10_HUMAN	sp|Q96BY6|DOC10_HUMAN Dedicator of cytokinesis protein 10 OS=Homo sapiens GN=DOCK10 PE=1 SV=3	9031.ENSGALP00000008043	Putative uncharacterized protein 	_	KOG1997	_	PF06920.10|DHR-2|Dock homology region 2|ENSGALT00000094155|m.8694:1609-2159;PF14429.3|DOCK-C2|C2 domain in Dock180 and Zizimin proteins|ENSGALT00000094155|m.8694:686-875;PF11878.5|DUF3398|Domain of unknown function (DUF3398)|ENSGALT00000094155|m.8694:76-167;PF00169.26|PH|PH domain|ENSGALT00000094155|m.8694:199-306
ENSGALG00000005031	0.179477032	0.485433493	-1.386668421	0.005518381	0.010253513	down	yes	0.050486511	0.30847295	0.179471635	0.411458879	0.512492256	0.532349343	4	2056879	2068479	-	DRP2	protein_coding	GO:0007417|central nervous system development; GO:0050808|synapse organization	GO:0014069|postsynaptic density; GO:0030054|cell junction; GO:0030425|dendrite; GO:0043204|perikaryon; GO:0045211|postsynaptic membrane	GO:0008270|zinc ion binding	--	--	3131	XP_025006058.1	XP_025006058.1 dystrophin-related protein 2 isoform X3 [Gallus gallus]	sp|Q13474|DRP2_HUMAN	sp|Q13474|DRP2_HUMAN Dystrophin-related protein 2 OS=Homo sapiens GN=DRP2 PE=2 SV=2	_	_	_	_	_	"PF09068.8|EF-hand_2|EF hand|ENSGALT00000008061|m.16107:374-491;PF09069.8|EF-hand_3|EF-hand|ENSGALT00000008061|m.16107:496-585;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000008061|m.16107:220-324;PF00569.14|ZZ|Zinc finger, ZZ type|ENSGALT00000008061|m.16107:592-632;PF00397.23|WW|WW domain|ENSGALT00000008061|m.16107:344-370"
ENSGALG00000005036	1.122088326	3.149792428	-1.480843267	9.45E-14	5.73E-13	down	yes	1.422693688	1.055687961	0.887883328	3.397839821	2.881142352	3.170395112	17	5276316	5295621	+	SH2D3C	protein_coding	GO:0007165|signal transduction; GO:0007254|JNK cascade; GO:0007264|small GTPase mediated signal transduction	GO:0005737|cytoplasm; GO:0016020|membrane	GO:0005068|transmembrane receptor protein tyrosine kinase adaptor activity; GO:0005070|SH3/SH2 adaptor activity; GO:0005085|guanyl-nucleotide exchange factor activity	--	--	2778	XP_415508.4	XP_415508.4 SH2 domain-containing protein 3C isoform X1 [Gallus gallus]	sp|Q9QZS8|SH2D3_MOUSE	sp|Q9QZS8|SH2D3_MOUSE SH2 domain-containing protein 3C OS=Mus musculus GN=Sh2d3c PE=1 SV=1	_	_	_	_	_	PF00017.21|SH2|SH2 domain|ENSGALT00000095589|m.11941:273-353;PF00617.16|RasGEF|RasGEF domain|ENSGALT00000095589|m.11941:697-806
ENSGALG00000005043	4.296457562	12.89317334	-1.583152399	1.30E-40	3.38E-39	down	yes	4.051625412	3.79014638	5.047600893	13.00289664	12.69292656	12.98369681	15	6963505	6970903	+	ENSGALG00000005043	protein_coding	GO:0006084|acetyl-CoA metabolic process; GO:0006633|fatty acid biosynthetic process; GO:0006768|biotin metabolic process; GO:0006853|carnitine shuttle; GO:0010629|negative regulation of gene expression; GO:0010884|positive regulation of lipid storage; GO:0010906|regulation of glucose metabolic process; GO:0014070|response to organic cyclic compound; GO:0031325|positive regulation of cellular metabolic process; GO:0031667|response to nutrient levels; GO:0031999|negative regulation of fatty acid beta-oxidation; GO:0042493|response to drug; GO:0043086|negative regulation of catalytic activity; GO:0045540|regulation of cholesterol biosynthetic process; GO:0051289|protein homotetramerization; GO:0060421|positive regulation of heart growth; GO:0097009|energy homeostasis; GO:2001295|malonyl-CoA biosynthetic process	GO:0005634|nucleus; GO:0005739|mitochondrion; GO:0005741|mitochondrial outer membrane; GO:0005829|cytosol; GO:0012505|endomembrane system	GO:0003989|acetyl-CoA carboxylase activity; GO:0004075|biotin carboxylase activity; GO:0005524|ATP binding; GO:0009374|biotin binding; GO:0042802|identical protein binding; GO:0046872|metal ion binding	ko:K01946|ACACB	ko00061|Fatty acid biosynthesis; ko00254|Aflatoxin biosynthesis; ko00620|Pyruvate metabolism; ko00640|Propanoate metabolism; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko04152|AMPK signaling pathway; ko04910|Insulin signaling pathway; ko04920|Adipocytokine signaling pathway; ko04922|Glucagon signaling pathway; ko04931|Insulin resistance	2640	XP_025011460.1	XP_025011460.1 LOW QUALITY PROTEIN: acetyl-CoA carboxylase 2 [Gallus gallus]	sp|O00763|ACACB_HUMAN	sp|O00763|ACACB_HUMAN Acetyl-CoA carboxylase 2 OS=Homo sapiens GN=ACACB PE=1 SV=3	9031.ENSGALP00000021884	Acetyl-CoA carboxylase beta Fragment (EC 6.3.4.14)(EC 6.4.1.2)	COG0439;COG0511;COG4799	KOG0368	_	"PF08326.9|ACC_central|Acetyl-CoA carboxylase, central region|ENSGALT00000061031|m.10655:28-354;PF01039.19|Carboxyl_trans|Carboxyl transferase domain|ENSGALT00000061031|m.10655:432-818"
ENSGALG00000005062	0.278235528	0.933296725	-1.710463483	1.44E-05	3.97E-05	down	yes	0.232678434	0.263654592	0.338373559	1.177562963	0.945332014	0.676995198	15	6973568	6988195	-	FOXN4	protein_coding	"GO:0001947|heart looping; GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated; GO:0008016|regulation of heart contraction; GO:0010842|retina layer formation; GO:0035881|amacrine cell differentiation; GO:0036302|atrioventricular canal development; GO:0045893|positive regulation of transcription, DNA-templated; GO:0060579|ventral spinal cord interneuron fate commitment"	GO:0005634|nucleus	GO:0001158|enhancer sequence-specific DNA binding; GO:0003682|chromatin binding; GO:0003700|DNA-binding transcription factor activity; GO:0043565|sequence-specific DNA binding	ko:K09407|FOXN	--	2491	NP_001076828.1	NP_001076828.1 forkhead box protein N4 [Gallus gallus]	sp|Q3BJS1|FOXN4_XENLA	sp|Q3BJS1|FOXN4_XENLA Forkhead box protein N4 OS=Xenopus laevis GN=foxn4 PE=2 SV=1	_	_	_	_	_	PF00250.15|Forkhead|Forkhead domain|ENSGALT00000008117|m.10656:264-349
ENSGALG00000005086	0.898350784	3.555601493	-1.972824024	1.11E-18	9.65E-18	down	yes	0.607390076	1.12925229	0.958409987	3.533104893	3.508935965	3.62476362	6	16341344	16349555	-	PLAU	protein_coding	--	GO:0005576|extracellular region	GO:0004252|serine-type endopeptidase activity	ko:K01348|PLAU	ko04064|NF-kappa B signaling pathway; ko04610|Complement and coagulation cascades; ko05202|Transcriptional misregulation in cancer; ko05205|Proteoglycans in cancer; ko05206|MicroRNAs in cancer	2429	NP_990774.2	NP_990774.2 urokinase-type plasminogen activator preproprotein [Gallus gallus]	sp|P15120|UROK_CHICK	sp|P15120|UROK_CHICK Urokinase-type plasminogen activator OS=Gallus gallus GN=PLAU PE=2 SV=1	9031.ENSGALP00000008143	Urokinase-type plasminogen activator Precursor (U-plasminogen activator)(uPA)(EC 3.4.21.73)  [...] 	COG5640	KOG1217;KOG3627	_	PF00089.23|Trypsin|Trypsin|ENSGALT00000008157|m.4716:173-416;PF00051.15|Kringle|Kringle domain|ENSGALT00000008157|m.4716:79-158
ENSGALG00000005093	44.48119869	19.40396408	1.19642524	1.99E-69	1.27E-67	up	yes	44.75070721	44.65696263	44.03592622	19.40530946	18.9240386	19.88254419	19	7348128	7352660	+	ENSGALG00000005093	protein_coding	"GO:0000184|nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0045859|regulation of protein kinase activity"	--	--	ko:K18734|SMG8	--	2296	XP_415875.5	XP_415875.5 protein SMG8 [Gallus gallus]	sp|A1A4J7|SMG8_BOVIN	sp|A1A4J7|SMG8_BOVIN Protein SMG8 OS=Bos taurus GN=SMG8 PE=2 SV=2	9031.ENSGALP00000008152	chromosome 17 open reading frame 71	_	KOG3692	_	PF10220.6|DUF2146|Uncharacterized conserved protein (DUF2146)|ENSGALT00000072898|m.14101:1-688
ENSGALG00000005099	14.99000603	7.401951388	1.017037756	6.11E-08	2.22E-07	up	yes	12.70289479	17.0118924	15.2552309	9.19066538	5.562228653	7.452960131	17	5160792	5162562	+	ORM1	protein_coding	--	--	--	"ko:K17308|ORM1,AGP1"	--	813	NP_989872.1	NP_989872.1 orosomucoid 1 (ovoglycoprotein) precursor [Gallus gallus]	_	_	_	_	_	_	_	PF11032.5|ApoM|ApoM domain|ENSGALT00000008177|m.11910:57-197;PF00061.20|Lipocalin|Lipocalin / cytosolic fatty-acid binding protein family|ENSGALT00000008177|m.11910:61-197
ENSGALG00000005102	1.940934168	4.715752618	-1.276379013	6.29E-17	4.81E-16	down	yes	1.80000615	1.972983623	2.04981273	4.595862656	4.537437205	5.013957992	20	7236310	7648851	+	CDH4	protein_coding	GO:0007156|homophilic cell adhesion via plasma membrane adhesion molecules	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0005509|calcium ion binding	ko:K06797|CDH4	ko04514|Cell adhesion molecules (CAMs)	2785	XP_015151860.1	XP_015151860.1 cadherin-4 isoform X1 [Gallus gallus]	sp|P24503|CADH4_CHICK	sp|P24503|CADH4_CHICK Cadherin-4 OS=Gallus gallus GN=CDH4 PE=2 SV=1	9031.ENSGALP00000008166	Cadherin-4 Precursor (Retinal cadherin)(R-cadherin)(R-CAD); Cadherins are calcium dependent  [...] 	_	KOG3594	_	PF00028.14|Cadherin|Cadherin domain|ENSGALT00000097753|m.3109:123-214;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000097753|m.3109:229-330;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000097753|m.3109:344-446;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000097753|m.3109:461-551;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000097753|m.3109:566-658;PF01049.14|Cadherin_C|Cadherin cytoplasmic region|ENSGALT00000097753|m.3109:709-859;PF08758.8|Cadherin_pro|Cadherin prodomain like|ENSGALT00000097753|m.3109:6-65
ENSGALG00000005118	0.993599792	0.270340095	1.839934073	0.000112002	0.000272681	up	yes	1.136536374	0.810161971	1.03410103	0.166252371	0.174803993	0.469963921	9	8549021	8551673	-	FAM124B	protein_coding	--	GO:0005654|nucleoplasm; GO:0005739|mitochondrion	--	--	--	1669	XP_001234634.2	XP_001234634.2 protein FAM124B [Gallus gallus]	sp|A6QLD5|F124B_BOVIN	sp|A6QLD5|F124B_BOVIN Protein FAM124B OS=Bos taurus GN=FAM124B PE=2 SV=1	9031.ENSGALP00000008206	family with sequence similarity 124B	_	_	NOG44601	PF15067.3|FAM124|FAM124 family|ENSGALT00000040805|m.8684:10-244
ENSGALG00000005122	0.271521753	0.739003704	-1.411726448	0.000860187	0.001827614	down	yes	0.076831568	0.292931455	0.444802237	0.826541572	0.595577442	0.794892097	15	7006773	7029577	+	MYO1H	protein_coding	--	GO:0016459|myosin complex	GO:0003774|motor activity; GO:0003779|actin binding; GO:0005524|ATP binding	ko:K10356|MYO1	--	3429	XP_003642232.2	XP_003642232.2 unconventional myosin-Ih isoform X1 [Gallus gallus]	sp|Q8N1T3|MYO1H_HUMAN	sp|Q8N1T3|MYO1H_HUMAN Unconventional myosin-Ih OS=Homo sapiens GN=MYO1H PE=1 SV=2	9031.ENSGALP00000008212	myosin IH	COG5022	KOG0164	_	"PF00063.18|Myosin_head|Myosin head (motor domain)|ENSGALT00000008227|m.10657:36-699;PF06017.10|Myosin_TH1|Unconventional myosin tail, actin- and lipid-binding|ENSGALT00000008227|m.10657:855-1019"
ENSGALG00000005128	2.19785731	7.020789232	-1.67103971	3.82E-28	5.49E-27	down	yes	1.990847195	2.530130881	2.072593854	6.956017565	6.771405987	7.334944145	12	6506037	6514868	-	PTPDC1	protein_coding	GO:0060271|cilium assembly	GO:0005634|nucleus; GO:0005737|cytoplasm	GO:0004725|protein tyrosine phosphatase activity; GO:0008138|protein tyrosine/serine/threonine phosphatase activity	ko:K18078|PTPDC1	--	2382	XP_414322.2	XP_414322.2 protein tyrosine phosphatase domain-containing protein 1 isoform X3 [Gallus gallus]	sp|A7E379|PTPC1_BOVIN	sp|A7E379|PTPC1_BOVIN Protein tyrosine phosphatase domain-containing protein 1 OS=Bos taurus GN=PTPDC1 PE=2 SV=2	59729.ENSTGUP00000003857	Protein tyrosine phosphatase domain-containing protein 1 (EC 3.1.3.-) [Taeniopygia guttata]	_	KOG1720	_	"PF00782.17|DSPc|Dual specificity phosphatase, catalytic domain|ENSGALT00000099251|m.7511:101-233;PF00102.24|Y_phosphatase|Protein-tyrosine phosphatase|ENSGALT00000099251|m.7511:151-231"
ENSGALG00000005173	7.157754322	16.30257543	-1.186391479	1.16E-26	1.57E-25	down	yes	7.840249582	6.826317391	6.806695992	16.36097564	15.64074983	16.90600083	19	7521816	7528589	-	TUBD1	protein_coding	GO:0007017|microtubule-based process; GO:0007275|multicellular organism development; GO:0007283|spermatogenesis; GO:0030154|cell differentiation	GO:0005654|nucleoplasm; GO:0005814|centriole; GO:0005829|cytosol; GO:0005874|microtubule	GO:0003924|GTPase activity; GO:0005200|structural constituent of cytoskeleton; GO:0005525|GTP binding	ko:K10390|TUBD	--	1828	XP_415881.1	XP_415881.1 tubulin delta chain isoform X2 [Gallus gallus]	sp|Q8HZV4|TBD_CANLF	sp|Q8HZV4|TBD_CANLF Tubulin delta chain OS=Canis lupus familiaris GN=TUBD1 PE=2 SV=1	9031.ENSGALP00000008290	"tubulin, delta 1"	COG5023	KOG1374	_	"PF00091.22|Tubulin|Tubulin/FtsZ family, GTPase domain|ENSGALT00000066374|m.14114:3-213"
ENSGALG00000005180	0.541505371	1.104547995	-1.015011901	0.002528613	0.004987468	down	yes	0.395133777	0.506996749	0.722385589	0.839753026	1.05484926	1.419041699	8	11693571	11741165	+	ENSGALG00000005180	protein_coding	GO:0001502|cartilage condensation; GO:0001503|ossification; GO:0002063|chondrocyte development; GO:0003007|heart morphogenesis; GO:0006029|proteoglycan metabolic process; GO:0007601|visual perception; GO:0007605|sensory perception of sound; GO:0030199|collagen fibril organization; GO:0035987|endodermal cell differentiation; GO:0035989|tendon development; GO:0042472|inner ear morphogenesis; GO:0048704|embryonic skeletal system morphogenesis; GO:0048705|skeletal system morphogenesis; GO:0050910|detection of mechanical stimulus involved in sensory perception of sound; GO:0051216|cartilage development; GO:0055010|ventricular cardiac muscle tissue morphogenesis	GO:0005581|collagen trimer; GO:0005592|collagen type XI trimer; GO:0005615|extracellular space; GO:0031012|extracellular matrix	GO:0005201|extracellular matrix structural constituent; GO:0046872|metal ion binding	ko:K19721|COL5AS	ko04974|Protein digestion and absorption	2667	XP_422303.3	XP_422303.3 collagen alpha-1(XI) chain isoform X1 [Gallus gallus]	sp|Q61245|COBA1_MOUSE	sp|Q61245|COBA1_MOUSE Collagen alpha-1(XI) chain OS=Mus musculus GN=Col11a1 PE=1 SV=2	9031.ENSGALP00000008307	Alpha-1 type XI collagen Fragment 	_	KOG3544	_	PF01410.15|COLFI|Fibrillar collagen C-terminal domain|ENSGALT00000083237|m.7375:658-886;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000083237|m.7375:1-59;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000083237|m.7375:43-101;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000083237|m.7375:91-149;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000083237|m.7375:148-206;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000083237|m.7375:526-578;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000083237|m.7375:568-623
ENSGALG00000005229	7.14284786	14.78136664	-1.048165694	3.71E-11	1.82E-10	down	yes	5.977415354	7.397298669	8.053829558	18.00014814	11.92954967	14.41440211	8	12119346	12137301	+	DPH5	protein_coding	GO:0017183|peptidyl-diphthamide biosynthetic process from peptidyl-histidine	GO:0005829|cytosol	GO:0004164|diphthine synthase activity	ko:K00586|DPH5	--	1525	XP_422306.1	XP_422306.1 diphthine methyl ester synthase isoform X1 [Gallus gallus]	sp|Q9H2P9|DPH5_HUMAN	sp|Q9H2P9|DPH5_HUMAN Diphthine methyl ester synthase OS=Homo sapiens GN=DPH5 PE=1 SV=2	9031.ENSGALP00000008387	DPH5 homolog (S. cerevisiae)	COG1798	KOG3123	_	PF00590.17|TP_methylase|Tetrapyrrole (Corrin/Porphyrin) Methylases|ENSGALT00000008401|m.7388:1-239
ENSGALG00000005242	0.063583494	2.230229935	-4.928120817	1.00E-32	1.83E-31	down	yes	0.109285222	0.04578744	0.035677822	2.243291627	2.210491754	2.236906423	2	1572974	1597843	-	ENSGALG00000005242	protein_coding	GO:0007166|cell surface receptor signaling pathway	GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0043235|receptor complex	GO:0004999|vasoactive intestinal polypeptide receptor activity	--	--	3308	XP_425958.3	XP_425958.3 vasoactive intestinal polypeptide receptor 1 [Gallus gallus]	sp|P97751|VIPR1_MOUSE	sp|P97751|VIPR1_MOUSE Vasoactive intestinal polypeptide receptor 1 OS=Mus musculus GN=Vipr1 PE=1 SV=3	_	_	_	_	_	PF00002.21|7tm_2|7 transmembrane receptor (Secretin family)|ENSGALT00000090040|m.14524:138-378;PF02793.19|HRM|Hormone receptor domain|ENSGALT00000090040|m.14524:56-118
ENSGALG00000005259	12.58525526	81.35727802	-2.691568368	2.33E-246	2.56E-243	down	yes	12.22410094	12.42462567	13.10703918	78.31979086	87.41208684	78.33995637	2	1815087	1919770	+	VIPR1	protein_coding	GO:0007166|cell surface receptor signaling pathway	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0004999|vasoactive intestinal polypeptide receptor activity	ko:K04589|VIPR1	ko04080|Neuroactive ligand-receptor interaction	1818	NP_001090992.1	NP_001090992.1 vasoactive intestinal polypeptide receptor 1 precursor [Gallus gallus]	sp|Q91085|VIPR_MELGA	sp|Q91085|VIPR_MELGA Vasoactive intestinal polypeptide receptor OS=Meleagris gallopavo GN=VIPR1 PE=2 SV=2	9031.ENSGALP00000008429	Vasoactive intestinal peptide receptor Fragment 	_	KOG4564	_	PF00002.21|7tm_2|7 transmembrane receptor (Secretin family)|ENSGALT00000008443|m.14526:129-373;PF02793.19|HRM|Hormone receptor domain|ENSGALT00000008443|m.14526:51-114
ENSGALG00000005263	2.047395026	4.295715635	-1.06543422	6.92E-06	1.99E-05	down	yes	2.54798819	2.275356149	1.318840739	4.927267662	4.069638527	3.890240718	14	6145956	6149345	-	SOX8	protein_coding	"GO:0003170|heart valve development; GO:0006351|transcription, DNA-templated; GO:0048709|oligodendrocyte differentiation"	GO:0005634|nucleus	"GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0003677|DNA binding"	ko:K09270|SOX7S	--	1613	NP_990062.1	NP_990062.1 transcription factor SOX-8 [Gallus gallus]	sp|P57074|SOX8_CHICK	sp|P57074|SOX8_CHICK Transcription factor SOX-8 OS=Gallus gallus GN=SOX8 PE=2 SV=1	9031.ENSGALP00000008435	"Transcription factor SOX-8 ; May play a role in central nervous system, limb and facial deve [...] "	_	KOG0527	_	PF00505.16|HMG_box|HMG (high mobility group) box|ENSGALT00000008449|m.9483:109-177;PF12444.5|Sox_N|Sox developmental protein N terminal|ENSGALT00000008449|m.9483:22-98;PF09011.7|HMG_box_2|HMG-box domain|ENSGALT00000008449|m.9483:109-176
ENSGALG00000005294	1.334235153	4.446435345	-1.729104637	4.70E-36	9.75E-35	down	yes	1.233983351	1.316011149	1.452710959	4.772414916	4.316899416	4.249991701	5	7591669	7664920	+	PPFIBP2	protein_coding	--	GO:0005615|extracellular space; GO:0005622|intracellular; GO:0005829|cytosol	GO:0042802|identical protein binding	--	--	4267	XP_025006798.1	XP_025006798.1 liprin-beta-2 isoform X4 [Gallus gallus]	sp|Q8ND30|LIPB2_HUMAN	sp|Q8ND30|LIPB2_HUMAN Liprin-beta-2 OS=Homo sapiens GN=PPFIBP2 PE=1 SV=3	9031.ENSGALP00000008476	annotation not avaliable	_	KOG1899	_	PF00536.27|SAM_1|SAM domain (Sterile alpha motif)|ENSGALT00000099079|m.2397:536-597;PF00536.27|SAM_1|SAM domain (Sterile alpha motif)|ENSGALT00000099079|m.2397:613-669;PF07647.14|SAM_2|SAM domain (Sterile alpha motif)|ENSGALT00000099079|m.2397:537-598;PF07647.14|SAM_2|SAM domain (Sterile alpha motif)|ENSGALT00000099079|m.2397:614-666;PF07647.14|SAM_2|SAM domain (Sterile alpha motif)|ENSGALT00000099079|m.2397:694-763
ENSGALG00000005298	9.235084013	4.258631166	1.114912919	6.08E-10	2.68E-09	up	yes	9.947580244	8.167283917	9.590387879	4.423856734	3.647360572	4.704676191	17	5241069	5246953	+	ENSGALG00000005298	protein_coding	GO:0001574|ganglioside biosynthetic process; GO:0006677|glycosylceramide metabolic process; GO:0006687|glycosphingolipid metabolic process; GO:0009100|glycoprotein metabolic process; GO:0009311|oligosaccharide metabolic process; GO:0009312|oligosaccharide biosynthetic process; GO:0009988|cell-cell recognition; GO:0018279|protein N-linked glycosylation via asparagine	GO:0000139|Golgi membrane; GO:0005737|cytoplasm; GO:0005886|plasma membrane; GO:0016021|integral component of membrane	"GO:0001665|alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity; GO:0008373|sialyltransferase activity"	"ko:K03376|SIAT7F,ST6GalNAcVI"	ko00604|Glycosphingolipid biosynthesis - ganglio series; ko01100|Metabolic pathways	993	POI21119.1	POI21119.1 hypothetical protein CIB84_015134 [Bambusicola thoracicus]	sp|Q969X2|SIA7F_HUMAN	"sp|Q969X2|SIA7F_HUMAN Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 OS=Homo sapiens GN=ST6GALNAC6 PE=1 SV=1"	_	_	_	_	_	PF00777.15|Glyco_transf_29|Glycosyltransferase family 29 (sialyltransferase)|ENSGALT00000096871|m.11923:102-313
ENSGALG00000005318	2.994720135	7.360498288	-1.294531535	1.89E-22	2.05E-21	down	yes	2.938092487	2.69633153	3.349736387	7.172549686	7.349103457	7.559841721	5	7676131	7692468	-	OVCH2	protein_coding	--	GO:0005576|extracellular region	GO:0004252|serine-type endopeptidase activity; GO:0046872|metal ion binding	ko:K20111|OVCH2	--	2708	XP_025006819.1	XP_025006819.1 ovochymase-2 isoform X4 [Gallus gallus]	sp|P79953|OVCH2_XENLA	sp|P79953|OVCH2_XENLA Ovochymase-2 OS=Xenopus laevis GN=ovch2 PE=1 SV=1	9031.ENSGALP00000008508	ovochymase 2	COG5640	KOG3627	_	PF00089.23|Trypsin|Trypsin|ENSGALT00000008522|m.2401:53-297;PF00089.23|Trypsin|Trypsin|ENSGALT00000008522|m.2401:597-830;PF00431.17|CUB|CUB domain|ENSGALT00000008522|m.2401:319-424;PF00431.17|CUB|CUB domain|ENSGALT00000008522|m.2401:443-545;PF09342.8|DUF1986|Domain of unknown function (DUF1986)|ENSGALT00000008522|m.2401:65-179;PF09342.8|DUF1986|Domain of unknown function (DUF1986)|ENSGALT00000008522|m.2401:608-722
ENSGALG00000005319	0.137893458	0.33902224	-1.238760728	0.010218898	0.018047383	down	yes	0.162752399	0.188939484	0.061988493	0.260180835	0.423755861	0.333130024	11	12824211	12973016	+	CDH8	protein_coding	"GO:0007155|cell adhesion; GO:0007156|homophilic cell adhesion via plasma membrane adhesion molecules; GO:0009409|response to cold; GO:0034332|adherens junction organization; GO:0035249|synaptic transmission, glutamatergic"	GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0043083|synaptic cleft; GO:0043679|axon terminus	GO:0005509|calcium ion binding; GO:0042802|identical protein binding	ko:K06800|CDH8	--	3650	XP_015147997.2	XP_015147997.2 cadherin-8 isoform X1 [Gallus gallus]	sp|P55286|CADH8_HUMAN	sp|P55286|CADH8_HUMAN Cadherin-8 OS=Homo sapiens GN=CDH8 PE=2 SV=2	_	_	_	_	_	PF00028.14|Cadherin|Cadherin domain|ENSGALT00000008525|m.6715:75-158;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000008525|m.6715:172-266;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000008525|m.6715:281-382;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000008525|m.6715:397-487;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000008525|m.6715:502-597;PF01049.14|Cadherin_C|Cadherin cytoplasmic region|ENSGALT00000008525|m.6715:645-791
ENSGALG00000005331	0.308766566	0.97645066	-1.629746572	3.90E-07	1.31E-06	down	yes	0.270782501	0.3036463	0.351870897	0.874749101	1.165429152	0.889173728	2	2396097	2402774	-	GJC2	protein_coding	GO:0001570|vasculogenesis; GO:0007268|chemical synaptic transmission; GO:0007601|visual perception; GO:0016264|gap junction assembly; GO:0048468|cell development; GO:0048738|cardiac muscle tissue development	GO:0005922|connexin complex; GO:0016021|integral component of membrane	GO:0005216|ion channel activity; GO:0086077|gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling	"ko:K07619|GJA12,CX47"	--	3308	NP_001186510.1	NP_001186510.1 gap junction gamma-2 protein [Gallus gallus]	sp|P18861|CXG1_CHICK	sp|P18861|CXG1_CHICK Gap junction gamma-1 protein OS=Gallus gallus GN=GJC1 PE=2 SV=1	9031.ENSGALP00000038397	"gap junction protein, gamma 12, 47kDa"	_	_	NOG44555	PF00029.16|Connexin|Connexin|ENSGALT00000008553|m.14546:5-258
ENSGALG00000005332	0.607040732	1.318413674	-1.106266845	1.02E-09	4.40E-09	down	yes	0.617164057	0.759710603	0.444247537	1.26082499	1.345832691	1.348583339	12	7450925	7616503	+	CACNA1D	protein_coding	GO:0007188|adenylate cyclase-modulating G protein-coupled receptor signaling pathway; GO:0007605|sensory perception of sound; GO:0051928|positive regulation of calcium ion transport; GO:0060372|regulation of atrial cardiac muscle cell membrane repolarization; GO:0070509|calcium ion import; GO:0086002|cardiac muscle cell action potential involved in contraction; GO:0086010|membrane depolarization during action potential; GO:0086091|regulation of heart rate by cardiac conduction; GO:1901016|regulation of potassium ion transmembrane transporter activity	GO:0005886|plasma membrane; GO:0030018|Z disc; GO:1990454|L-type voltage-gated calcium channel complex	GO:0008331|high voltage-gated calcium channel activity; GO:0030506|ankyrin binding; GO:0046872|metal ion binding; GO:0051393|alpha-actinin binding; GO:0086059|voltage-gated calcium channel activity involved SA node cell action potential	ko:K04851|CACNA1D	ko04010|MAPK signaling pathway; ko04020|Calcium signaling pathway; ko04022|cGMP-PKG signaling pathway; ko04024|cAMP signaling pathway; ko04260|Cardiac muscle contraction; ko04261|Adrenergic signaling in cardiomyocytes; ko04270|Vascular smooth muscle contraction; ko04530|Tight junction; ko04713|Circadian entrainment; ko04723|Retrograde endocannabinoid signaling; ko04724|Glutamatergic synapse; ko04725|Cholinergic synapse; ko04726|Serotonergic synapse; ko04727|GABAergic synapse; ko04728|Dopaminergic synapse; ko04911|Insulin secretion; ko04912|GnRH signaling pathway; ko04921|Oxytocin signaling pathway; ko04924|Renin secretion; ko04925|Aldosterone synthesis and secretion; ko04930|Type II diabetes mellitus; ko04973|Carbohydrate digestion and absorption; ko05010|Alzheimer's disease; ko05031|Amphetamine addiction; ko05410|Hypertrophic cardiomyopathy (HCM); ko05412|Arrhythmogenic right ventricular cardiomyopathy (ARVC); ko05414|Dilated cardiomyopathy	8718	NP_990365.1	NP_990365.1 voltage-dependent L-type calcium channel subunit alpha-1D [Gallus gallus]	sp|O73700|CAC1D_CHICK	sp|O73700|CAC1D_CHICK Voltage-dependent L-type calcium channel subunit alpha-1D OS=Gallus gallus GN=CACNA1D PE=2 SV=1	_	_	_	_	_	"PF00520.28|Ion_trans|Ion transport protein|ENSGALT00000036264|m.7593:121-411;PF00520.28|Ion_trans|Ion transport protein|ENSGALT00000036264|m.7593:545-780;PF00520.28|Ion_trans|Ion transport protein|ENSGALT00000036264|m.7593:906-1183;PF00520.28|Ion_trans|Ion transport protein|ENSGALT00000036264|m.7593:1228-1503;PF16885.2|CAC1F_C|Voltage-gated calcium channel subunit alpha, C-term|ENSGALT00000036264|m.7593:1671-2189;PF16905.2|GPHH|Voltage-dependent L-type calcium channel, IQ-associated|ENSGALT00000036264|m.7593:1505-1575;PF08763.8|Ca_chan_IQ|Voltage gated calcium channel IQ domain|ENSGALT00000036264|m.7593:1576-1650;PF08016.9|PKD_channel|Polycystin cation channel|ENSGALT00000036264|m.7593:1270-1497"
ENSGALG00000005345	2.187890699	6.217879478	-1.502621383	4.28E-14	2.67E-13	down	yes	2.126710625	2.258305353	2.178656119	6.68930688	5.26416516	6.700166393	20	7941683	7956242	-	CABLES2	protein_coding	GO:0007049|cell cycle; GO:0051301|cell division; GO:0051726|regulation of cell cycle	--	--	--	--	1437	XP_015152141.1	XP_015152141.1 CDK5 and ABL1 enzyme substrate 2 isoform X1 [Gallus gallus]	sp|Q8K3M5|CABL2_MOUSE	sp|Q8K3M5|CABL2_MOUSE CDK5 and ABL1 enzyme substrate 2 OS=Mus musculus GN=Cables2 PE=1 SV=2	9031.ENSGALP00000008556	Cdk5 and Abl enzyme substrate 2	_	KOG4164	_	"PF00134.20|Cyclin_N|Cyclin, N-terminal domain|ENSGALT00000066890|m.3159:362-460"
ENSGALG00000005347	0.815980598	2.409232098	-1.550369387	1.32E-16	9.85E-16	down	yes	0.798544983	0.727145619	0.922251193	2.55800031	2.210751354	2.458944632	11	13794910	13862852	-	ADAMTS18	protein_coding	GO:0001654|eye development; GO:0090331|negative regulation of platelet aggregation	GO:0031012|extracellular matrix	GO:0004222|metalloendopeptidase activity; GO:0008270|zinc ion binding	ko:K08632|ADAMTS18	--	4091	XP_004944310.3	XP_004944310.3 A disintegrin and metalloproteinase with thrombospondin motifs 18 isoform X2 [Gallus gallus]	sp|Q8TE60|ATS18_HUMAN	sp|Q8TE60|ATS18_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 18 OS=Homo sapiens GN=ADAMTS18 PE=1 SV=3	9031.ENSGALP00000008559	similar to ADAMTS18 protein	_	KOG3538	_	PF01562.16|Pep_M12B_propep|Reprolysin family propeptide|ENSGALT00000094853|m.6720:24-163;PF05986.11|ADAM_spacer1|ADAM-TS Spacer 1|ENSGALT00000094853|m.6720:713-821;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000094853|m.6720:555-605;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000094853|m.6720:899-952;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000094853|m.6720:960-985;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000094853|m.6720:1024-1079;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000094853|m.6720:1094-1141;PF01421.16|Reprolysin|Reprolysin (M12B) family zinc metalloprotease|ENSGALT00000094853|m.6720:257-460;PF13688.3|Reprolysin_5|Metallo-peptidase family M12|ENSGALT00000094853|m.6720:257-435;PF08686.8|PLAC|PLAC (protease and lacunin) domain|ENSGALT00000094853|m.6720:1152-1182;PF13574.3|Reprolysin_2|Metallo-peptidase family M12B Reprolysin-like|ENSGALT00000094853|m.6720:275-445;PF13582.3|Reprolysin_3|Metallo-peptidase family M12B Reprolysin-like|ENSGALT00000094853|m.6720:278-409
ENSGALG00000005350	14.48133079	37.36840816	-1.367015041	7.29E-95	8.00E-93	down	yes	14.36849658	14.62265903	14.45283676	36.06350796	39.71615285	36.32556365	19	8169952	8266166	+	ENSGALG00000005350	protein_coding	GO:0006511|ubiquitin-dependent protein catabolic process; GO:0016579|protein deubiquitination	GO:0005794|Golgi apparatus; GO:0005829|cytosol; GO:0016020|membrane	GO:0004843|thiol-dependent ubiquitin-specific protease activity; GO:0005509|calcium ion binding	ko:K11837|USP6_32	--	5125	XP_004946798.2	XP_004946798.2 ubiquitin carboxyl-terminal hydrolase 32 isoform X3 [Gallus gallus]	sp|Q8NFA0|UBP32_HUMAN	sp|Q8NFA0|UBP32_HUMAN Ubiquitin carboxyl-terminal hydrolase 32 OS=Homo sapiens GN=USP32 PE=1 SV=1	9031.ENSGALP00000008566	ubiquitin specific peptidase 32	COG5126;COG5560	KOG0044;KOG1870	_	PF00443.26|UCH|Ubiquitin carboxyl-terminal hydrolase|ENSGALT00000080001|m.14141:737-1574;PF06337.9|DUSP|DUSP domain|ENSGALT00000080001|m.14141:445-588;PF13423.3|UCH_1|Ubiquitin carboxyl-terminal hydrolase|ENSGALT00000080001|m.14141:1225-1555;PF13202.3|EF-hand_5|EF hand|ENSGALT00000080001|m.14141:288-304;PF13202.3|EF-hand_5|EF hand|ENSGALT00000080001|m.14141:324-345;PF14836.3|Ubiquitin_3|Ubiquitin-like domain|ENSGALT00000080001|m.14141:644-713
ENSGALG00000005352	5.167940709	12.96104607	-1.324844482	2.12E-24	2.56E-23	down	yes	4.974038811	5.006856537	5.52292678	13.75219982	11.33648844	13.79444995	20	8019682	8030097	-	GATA5	protein_coding	GO:0030154|cell differentiation	GO:0005634|nucleus; GO:0005667|transcription factor complex	"GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding; GO:0001085|RNA polymerase II transcription factor binding; GO:0001158|enhancer sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003682|chromatin binding; GO:0008270|zinc ion binding"	ko:K17896|GATA5	--	1875	NP_990752.2	NP_990752.2 transcription factor GATA-5 [Gallus gallus]	sp|P43692|GATA5_CHICK	sp|P43692|GATA5_CHICK Transcription factor GATA-5 OS=Gallus gallus GN=GATA5 PE=1 SV=1	9031.ENSGALP00000008569	Transcription factor GATA-5 (GATA-binding factor 5)	COG5641	KOG1601	_	"PF05349.9|GATA-N|GATA-type transcription activator, N-terminal|ENSGALT00000008583|m.3161:1-172;PF00320.24|GATA|GATA zinc finger|ENSGALT00000008583|m.3161:186-218;PF00320.24|GATA|GATA zinc finger|ENSGALT00000008583|m.3161:239-272"
ENSGALG00000005378	15.55494703	31.65491814	-1.024584683	2.73E-31	4.65E-30	down	yes	15.98867592	15.7972631	14.87890207	29.27576847	35.68380773	30.00517822	5	7820343	7864789	-	ARNTL	protein_coding	"GO:0007283|spermatogenesis; GO:0007623|circadian rhythm; GO:0032007|negative regulation of TOR signaling; GO:0032922|circadian regulation of gene expression; GO:0042176|regulation of protein catabolic process; GO:0042634|regulation of hair cycle; GO:0042753|positive regulation of circadian rhythm; GO:0043161|proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0045599|negative regulation of fat cell differentiation; GO:0045893|positive regulation of transcription, DNA-templated; GO:0050767|regulation of neurogenesis; GO:0050796|regulation of insulin secretion; GO:0051726|regulation of cell cycle; GO:0051775|response to redox state; GO:0060137|maternal process involved in parturition; GO:0090263|positive regulation of canonical Wnt signaling pathway; GO:0090403|oxidative stress-induced premature senescence; GO:2000074|regulation of type B pancreatic cell development; GO:2000323|negative regulation of glucocorticoid receptor signaling pathway; GO:2000772|regulation of cellular senescence; GO:2001016|positive regulation of skeletal muscle cell differentiation"	GO:0005667|transcription factor complex; GO:0016605|PML body; GO:0033391|chromatoid body	"GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0001046|core promoter sequence-specific DNA binding; GO:0003677|DNA binding; GO:0017162|aryl hydrocarbon receptor binding; GO:0043425|bHLH transcription factor binding; GO:0046982|protein heterodimerization activity; GO:0051879|Hsp90 protein binding; GO:0070491|repressing transcription factor binding; GO:0070888|E-box binding"	"ko:K02296|ARNTL,BMAL1,CYC"	ko04710|Circadian rhythm; ko04711|Circadian rhythm - fly; ko04728|Dopaminergic synapse; ko05168|Herpes simplex infection	2527	NP_001001463.1	NP_001001463.1 aryl hydrocarbon receptor nuclear translocator-like protein 1 [Gallus gallus]	sp|Q9I8T7|BMAL1_CHICK	sp|Q9I8T7|BMAL1_CHICK Aryl hydrocarbon receptor nuclear translocator-like protein 1 OS=Gallus gallus GN=ARNTL PE=1 SV=1	9031.ENSGALP00000032095	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) [...] 	_	KOG3561	_	PF14598.3|PAS_11|PAS domain|ENSGALT00000008634|m.2415:346-449;PF00989.22|PAS|PAS fold|ENSGALT00000008634|m.2415:156-259;PF00989.22|PAS|PAS fold|ENSGALT00000008634|m.2415:354-442;PF08447.9|PAS_3|PAS fold|ENSGALT00000008634|m.2415:358-444;PF00010.23|HLH|Helix-loop-helix DNA-binding domain|ENSGALT00000008634|m.2415:81-132;PF13426.4|PAS_9|PAS domain|ENSGALT00000008634|m.2415:166-241;PF13426.4|PAS_9|PAS domain|ENSGALT00000008634|m.2415:354-397
ENSGALG00000005401	1.406878188	4.4621642	-1.658257427	1.93E-10	8.91E-10	down	yes	1.540299803	0.847011865	1.833322896	5.335133194	3.680480277	4.370879129	2	2665702	2717022	+	WNT9A	protein_coding	GO:0016055|Wnt signaling pathway; GO:0030182|neuron differentiation; GO:0032331|negative regulation of chondrocyte differentiation; GO:0045165|cell fate commitment; GO:0061072|iris morphogenesis; GO:0061303|cornea development in camera-type eye; GO:0072498|embryonic skeletal joint development; GO:1902764|positive regulation of embryonic skeletal joint development	GO:0005615|extracellular space; GO:0031012|extracellular matrix	GO:0005109|frizzled binding	ko:K01064|WNT9	ko04150|mTOR signaling pathway; ko04310|Wnt signaling pathway; ko04390|Hippo signaling pathway; ko04550|Signaling pathways regulating pluripotency of stem cells; ko04916|Melanogenesis; ko05166|HTLV-I infection; ko05200|Pathways in cancer; ko05205|Proteoglycans in cancer; ko05217|Basal cell carcinoma; ko05224|Breast cancer	1642	NP_990312.2	NP_990312.2 protein Wnt-9a precursor [Gallus gallus]	sp|O42280|WNT9A_CHICK	sp|O42280|WNT9A_CHICK Protein Wnt-9a OS=Gallus gallus GN=WNT9A PE=2 SV=1	9031.ENSGALP00000008661	Protein Wnt-9a Precursor (Wnt-14); Ligand for members of the frizzled family of seven transm [...] 	_	KOG3913	_	PF00110.16|wnt|wnt family|ENSGALT00000008675|m.14565:204-502
ENSGALG00000005408	0.402490965	0.937448281	-1.199684673	0.00010737	0.000262357	down	yes	0.509913766	0.373869216	0.323689913	0.971802571	0.961289046	0.879253226	11	15458803	15472631	+	BCO1	protein_coding	GO:0001523|retinoid metabolic process; GO:0032526|response to retinoic acid; GO:0042572|retinol metabolic process; GO:0042574|retinal metabolic process; GO:1901810|beta-carotene metabolic process	--	"GO:0003834|beta-carotene 15,15'-monooxygenase activity; GO:0004497|monooxygenase activity; GO:0046872|metal ion binding"	"ko:K00515|BCMO1,BCDO1"	ko00830|Retinol metabolism; ko01100|Metabolic pathways	3100	NP_001351831.1	"NP_001351831.1 beta,beta-carotene 15,15'-dioxygenase [Gallus gallus]"	sp|Q9I993|BCDO1_CHICK	"sp|Q9I993|BCDO1_CHICK Beta,beta-carotene 15,15'-dioxygenase OS=Gallus gallus GN=BCO1 PE=1 SV=1"	9031.ENSGALP00000008671	"Beta,beta-carotene 15,15'-monooxygenase (EC 1.14.99.36)(Beta-carotene dioxygenase 1); Symmet [...] "	COG3670	KOG1285	_	PF03055.12|RPE65|Retinal pigment epithelial membrane protein|ENSGALT00000008685|m.6741:6-517
ENSGALG00000005421	1.210208974	2.612666563	-1.103906153	6.69E-05	0.000168262	down	yes	0.890374469	1.165755953	1.574496501	2.751068963	2.175721204	2.911209521	14	6525004	6528361	+	ENSGALG00000005421	protein_coding	GO:0006665|sphingolipid metabolic process; GO:0007165|signal transduction	GO:0005783|endoplasmic reticulum; GO:0016021|integral component of membrane	GO:0008289|lipid binding	--	--	1515	XP_414842.3	XP_414842.3 testis-expressed protein 2 isoform X1 [Gallus gallus]	sp|Q8IWB9|TEX2_HUMAN	sp|Q8IWB9|TEX2_HUMAN Testis-expressed protein 2 OS=Homo sapiens GN=TEX2 PE=1 SV=2	9031.ENSGALP00000008694	similar to KIAA1738 protein	_	KOG2238	_	PF10296.6|MMM1|Maintenance of mitochondrial morphology protein 1|ENSGALT00000008708|m.9513:191-285
ENSGALG00000005430	2.900712466	5.812159155	-1.000181947	5.86E-17	4.50E-16	down	yes	3.007213008	2.550756474	3.144167915	5.433992992	6.081967241	5.920517231	2	3313209	3355141	-	ALS2CL	protein_coding	--	GO:0005737|cytoplasm	GO:0005096|GTPase activator activity	--	--	3675	XP_004939151.1	XP_004939151.1 ALS2 C-terminal-like protein isoform X1 [Gallus gallus]	sp|A6QP75|AL2CL_BOVIN	sp|A6QP75|AL2CL_BOVIN ALS2 C-terminal-like protein OS=Bos taurus GN=ALS2CL PE=2 SV=1	_	_	_	_	_	PF02204.15|VPS9|Vacuolar sorting protein 9 (VPS9) domain|ENSGALT00000099765|m.14574:865-966;PF02493.17|MORN|MORN repeat|ENSGALT00000099765|m.14574:390-410;PF02493.17|MORN|MORN repeat|ENSGALT00000099765|m.14574:414-428;PF02493.17|MORN|MORN repeat|ENSGALT00000099765|m.14574:444-460;PF02493.17|MORN|MORN repeat|ENSGALT00000099765|m.14574:464-479;PF02493.17|MORN|MORN repeat|ENSGALT00000099765|m.14574:490-507;PF02493.17|MORN|MORN repeat|ENSGALT00000099765|m.14574:514-528;PF02493.17|MORN|MORN repeat|ENSGALT00000099765|m.14574:560-581
ENSGALG00000005474	2.001170868	0.96606937	1.042980067	0.000124632	0.000301247	up	yes	1.342292682	2.039916332	2.621303588	0.862921642	1.090700346	0.944586123	11	15793378	15797891	+	PNAT10	protein_coding	GO:0008152|metabolic process	--	GO:0004060|arylamine N-acetyltransferase activity	ko:K00622|nat	ko00232|Caffeine metabolism; ko00633|Nitrotoluene degradation; ko00983|Drug metabolism - other enzymes; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko01120|Microbial metabolism in diverse environments; ko05204|Chemical carcinogenesis	2159	POI34081.1	POI34081.1 hypothetical protein CIB84_002166 [Bambusicola thoracicus]	sp|P13913|ARY1_CHICK	"sp|P13913|ARY1_CHICK Arylamine N-acetyltransferase, pineal gland isozyme NAT-10 OS=Gallus gallus PE=2 SV=1"	9031.ENSGALP00000008780	"Arylamine N-acetyltransferase, pineal gland isozyme NAT-10 (Arylamine acetylase)(EC 2.3.1.5)"	COG2162	_	_	PF00797.14|Acetyltransf_2|N-acetyltransferase|ENSGALT00000008794|m.6753:20-280
ENSGALG00000005481	2.813631969	12.19348734	-2.111669514	3.10E-62	1.64E-60	down	yes	2.201468035	3.314707173	2.9247207	11.36143024	13.4954247	11.72360708	12	8830149	8941812	-	ARHGEF3	protein_coding	GO:0035023|regulation of Rho protein signal transduction; GO:0035556|intracellular signal transduction	GO:0005737|cytoplasm	GO:0005089|Rho guanyl-nucleotide exchange factor activity	ko:K20683|ARHGEF3_8	--	3729	NP_001025766.1	NP_001025766.1 rho guanine nucleotide exchange factor 3 [Gallus gallus]	sp|Q5ZLX4|ARHG3_CHICK	sp|Q5ZLX4|ARHG3_CHICK Rho guanine nucleotide exchange factor 3 OS=Gallus gallus GN=Arhgef3 PE=2 SV=1	9031.ENSGALP00000008791	Rho guanine nucleotide exchange factor 3 ; Acts as guanine nucleotide exchange factor (GEF)  [...] 	COG5422	KOG4305	_	PF00621.17|RhoGEF|RhoGEF domain|ENSGALT00000008805|m.7618:187-362
ENSGALG00000005504	2.116361603	4.268557086	-1.008737381	8.25E-06	2.35E-05	down	yes	2.641157349	2.299592399	1.408335062	4.408507822	4.256614918	4.140548519	19	8792517	8809163	-	HNF1B	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0001714|endodermal cell fate specification; GO:0001822|kidney development; GO:0001826|inner cell mass cell differentiation; GO:0006351|transcription, DNA-templated; GO:0007219|Notch signaling pathway; GO:0009749|response to glucose; GO:0009952|anterior/posterior pattern specification; GO:0030073|insulin secretion; GO:0030111|regulation of Wnt signaling pathway; GO:0030902|hindbrain development; GO:0031018|endocrine pancreas development; GO:0035565|regulation of pronephros size; GO:0039020|pronephric nephron tubule development; GO:0042663|regulation of endodermal cell fate specification; GO:0045893|positive regulation of transcription, DNA-templated; GO:0048557|embryonic digestive tract morphogenesis; GO:0048754|branching morphogenesis of an epithelial tube; GO:0048806|genitalia development; GO:0050673|epithelial cell proliferation; GO:0060261|positive regulation of transcription initiation from RNA polymerase II promoter; GO:0060677|ureteric bud elongation; GO:0061017|hepatoblast differentiation; GO:0061296|negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis; GO:0072095|regulation of branch elongation involved in ureteric bud branching; GO:0072181|mesonephric duct formation; GO:1900212|negative regulation of mesenchymal cell apoptotic process involved in metanephros development"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005667|transcription factor complex	"GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0003700|DNA-binding transcription factor activity; GO:0042803|protein homodimerization activity; GO:0044212|transcription regulatory region DNA binding; GO:0046982|protein heterodimerization activity"	"ko:K08034|TCF2,HNF1B"	ko04950|Maturity onset diabetes of the young	1596	XP_003642462.1	XP_003642462.1 hepatocyte nuclear factor 1-beta isoform X2 [Gallus gallus]	sp|Q5RER5|HNF1B_PONAB	sp|Q5RER5|HNF1B_PONAB Hepatocyte nuclear factor 1-beta OS=Pongo abelii GN=HNF1B PE=2 SV=1	9031.ENSGALP00000008820	"PREDICTED: Gallus gallus hypothetical LOC427838 (LOC427838), mRNA"	_	_	NOG79356	"PF04812.10|HNF-1B_C|Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus|ENSGALT00000008834|m.14182:286-524;PF04814.10|HNF-1_N|Hepatocyte nuclear factor 1 (HNF-1), N terminus|ENSGALT00000008834|m.14182:8-172;PF00046.26|Homeobox|Homeobox domain|ENSGALT00000008834|m.14182:204-277"
ENSGALG00000005517	0.375706105	0.860620947	-1.174542751	0.005918453	0.010927974	down	yes	0.28005894	0.161338146	0.685721229	0.812651113	0.838628745	0.930582983	2	4025276	4046080	-	KIF9	protein_coding	GO:0007018|microtubule-based movement; GO:0022617|extracellular matrix disassembly; GO:0071801|regulation of podosome assembly; GO:1903008|organelle disassembly	GO:0002102|podosome; GO:0005737|cytoplasm; GO:0005871|kinesin complex; GO:0005874|microtubule; GO:0031982|vesicle	GO:0003777|microtubule motor activity; GO:0005524|ATP binding; GO:0008017|microtubule binding; GO:0016887|ATPase activity; GO:0046983|protein dimerization activity	ko:K10397|KIF6_9	--	2537	XP_418511.3	XP_418511.3 kinesin-like protein KIF9 isoform X1 [Gallus gallus]	sp|Q9HAQ2|KIF9_HUMAN	sp|Q9HAQ2|KIF9_HUMAN Kinesin-like protein KIF9 OS=Homo sapiens GN=KIF9 PE=1 SV=4	9031.ENSGALP00000008837	annotation not avaliable	COG5059	KOG4280	_	PF00225.20|Kinesin|Kinesin motor domain|ENSGALT00000093902|m.14612:94-352;PF16796.2|Microtub_bd|Microtubule binding|ENSGALT00000093902|m.14612:101-166
ENSGALG00000005519	1.720213536	4.051428488	-1.231037142	4.66E-12	2.46E-11	down	yes	1.273771647	1.959938608	1.926930353	3.839763443	4.221751524	4.092770497	6	17425485	17478708	-	TLL2	protein_coding	GO:0007275|multicellular organism development; GO:0022617|extracellular matrix disassembly; GO:0030154|cell differentiation; GO:0048632|negative regulation of skeletal muscle tissue growth	GO:0005576|extracellular region	GO:0004222|metalloendopeptidase activity; GO:0004252|serine-type endopeptidase activity; GO:0005509|calcium ion binding; GO:0008270|zinc ion binding	ko:K13047|TLL2	--	2937	XP_015144007.1	XP_015144007.1 tolloid-like protein 2 isoform X1 [Gallus gallus]	sp|Q9Y6L7|TLL2_HUMAN	sp|Q9Y6L7|TLL2_HUMAN Tolloid-like protein 2 OS=Homo sapiens GN=TLL2 PE=1 SV=1	9031.ENSGALP00000008841	"PREDICTED: Gallus gallus similar to tolloid-like 2 protein (LOC423754), mRNA"	_	KOG3714	_	PF00431.17|CUB|CUB domain|ENSGALT00000061149|m.4759:314-423;PF00431.17|CUB|CUB domain|ENSGALT00000061149|m.4759:427-536;PF00431.17|CUB|CUB domain|ENSGALT00000061149|m.4759:583-692;PF00431.17|CUB|CUB domain|ENSGALT00000061149|m.4759:739-847;PF00431.17|CUB|CUB domain|ENSGALT00000061149|m.4759:860-965;PF01400.21|Astacin|Astacin (Peptidase family M12A)|ENSGALT00000061149|m.4759:121-312;PF14670.3|FXa_inhibition|Coagulation Factor Xa inhibitory site|ENSGALT00000061149|m.4759:699-734;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000061149|m.4759:540-579;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000061149|m.4759:695-734;PF12662.4|cEGF|Complement Clr-like EGF-like|ENSGALT00000061149|m.4759:561-580
ENSGALG00000005522	11.55830683	2.097543304	2.456543543	4.39E-89	4.24E-87	up	yes	11.13828795	12.24990359	11.28672895	2.017523659	1.942493301	2.332612952	19	8838677	8845322	-	DYNLL2	protein_coding	"GO:0010970|transport along microtubule; GO:0060271|cilium assembly; GO:2000582|positive regulation of ATP-dependent microtubule motor activity, plus-end-directed"	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005813|centrosome; GO:0005868|cytoplasmic dynein complex; GO:0005874|microtubule; GO:0016020|membrane; GO:0016459|myosin complex; GO:0031475|myosin V complex	GO:0003774|motor activity; GO:0008092|cytoskeletal protein binding; GO:0045505|dynein intermediate chain binding; GO:0051959|dynein light intermediate chain binding	ko:K10418|DYNLL	ko04962|Vasopressin-regulated water reabsorption	2085	KQK76746.1	"KQK76746.1 dynein light chain 2, cytoplasmic isoform X3 [Amazona aestiva]"	sp|Q3MHR3|DYL2_BOVIN	"sp|Q3MHR3|DYL2_BOVIN Dynein light chain 2, cytoplasmic OS=Bos taurus GN=DYNLL2 PE=3 SV=1"	_	_	_	_	_	_
ENSGALG00000005524	0.663107281	1.438605669	-1.105756559	0.002824185	0.005519106	down	yes	0.932255646	0.574165745	0.482900451	1.346558485	1.401074062	1.56818446	20	8227321	8272370	+	NTSR1	protein_coding	GO:0001659|temperature homeostasis; GO:0003085|negative regulation of systemic arterial blood pressure; GO:0003254|regulation of membrane depolarization; GO:0007186|G protein-coupled receptor signaling pathway; GO:0007218|neuropeptide signaling pathway; GO:0007268|chemical synaptic transmission; GO:0007612|learning; GO:0008344|adult locomotory behavior; GO:0014049|positive regulation of glutamate secretion; GO:0014054|positive regulation of gamma-aminobutyric acid secretion; GO:0033993|response to lipid; GO:0043065|positive regulation of apoptotic process; GO:0043066|negative regulation of apoptotic process; GO:0043576|regulation of respiratory gaseous exchange; GO:0050965|detection of temperature stimulus involved in sensory perception of pain; GO:0051280|negative regulation of release of sequestered calcium ion into cytosol; GO:0051281|positive regulation of release of sequestered calcium ion into cytosol; GO:0051930|regulation of sensory perception of pain; GO:0060732|positive regulation of inositol phosphate biosynthetic process; GO:0070779|D-aspartate import across plasma membrane; GO:0071545|inositol phosphate catabolic process; GO:0090238|positive regulation of arachidonic acid secretion; GO:0097151|positive regulation of inhibitory postsynaptic potential; GO:0098712|L-glutamate import across plasma membrane; GO:0098900|regulation of action potential; GO:2001259|positive regulation of cation channel activity	GO:0005739|mitochondrion; GO:0005783|endoplasmic reticulum; GO:0005794|Golgi apparatus; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0009898|cytoplasmic side of plasma membrane; GO:0009986|cell surface; GO:0032280|symmetric synapse; GO:0043195|terminal bouton; GO:0043197|dendritic spine; GO:0043198|dendritic shaft; GO:0043204|perikaryon; GO:0045121|membrane raft	GO:0004930|G protein-coupled receptor activity; GO:0016492|G protein-coupled neurotensin receptor activity; GO:0042802|identical protein binding; GO:0042803|protein homodimerization activity; GO:0046982|protein heterodimerization activity; GO:0047485|protein N-terminus binding	ko:K04211|NTSR1	ko04020|Calcium signaling pathway; ko04080|Neuroactive ligand-receptor interaction	1413	XP_021272551.1	XP_021272551.1 neurotensin receptor type 1 [Numida meleagris]	sp|P30989|NTR1_HUMAN	sp|P30989|NTR1_HUMAN Neurotensin receptor type 1 OS=Homo sapiens GN=NTSR1 PE=1 SV=2	_	_	_	_	_	PF00001.18|7tm_1|7 transmembrane receptor (rhodopsin family)|ENSGALT00000008861|m.3165:88-370
ENSGALG00000005537	2.185425292	5.805092114	-1.405301603	9.35E-13	5.23E-12	down	yes	1.989885931	2.178486084	2.387903862	5.331723748	7.244644325	4.838908268	12	9038049	9047098	-	ASB14	protein_coding	GO:0035556|intracellular signal transduction	GO:0000151|ubiquitin ligase complex; GO:0005634|nucleus; GO:0005737|cytoplasm	GO:0004842|ubiquitin-protein transferase activity; GO:0031625|ubiquitin protein ligase binding	ko:K10336|ASB14	--	1933	XP_414345.3	XP_414345.3 ankyrin repeat and SOCS box protein 14 [Gallus gallus]	sp|P0C927|ASB14_RAT	sp|P0C927|ASB14_RAT Ankyrin repeat and SOCS box protein 14 OS=Rattus norvegicus GN=Asb14 PE=3 SV=1	_	_	_	_	_	PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000008882|m.7625:56-149;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000008882|m.7625:123-212;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000008882|m.7625:186-245;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000008882|m.7625:255-343;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000008882|m.7625:357-415;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000008882|m.7625:121-172;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000008882|m.7625:186-238;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000008882|m.7625:252-299;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000008882|m.7625:318-378;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000008882|m.7625:119-147;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000008882|m.7625:151-179;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000008882|m.7625:185-212;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000008882|m.7625:217-244;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000008882|m.7625:119-149;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000008882|m.7625:186-212;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000008882|m.7625:217-245;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000008882|m.7625:316-343;PF07525.13|SOCS_box|SOCS box|ENSGALT00000008882|m.7625:533-574
ENSGALG00000005547	2.914626784	7.225543979	-1.306848953	1.06E-23	1.23E-22	down	yes	2.604310845	3.387792373	2.751777134	7.147969663	7.256483866	7.272178409	6	17555230	17600114	-	PIK3AP1	protein_coding	GO:0014068|positive regulation of phosphatidylinositol 3-kinase signaling; GO:0031929|TOR signaling; GO:0032869|cellular response to insulin stimulus; GO:0034134|toll-like receptor 2 signaling pathway; GO:0034142|toll-like receptor 4 signaling pathway; GO:0034154|toll-like receptor 7 signaling pathway; GO:0034162|toll-like receptor 9 signaling pathway; GO:0042325|regulation of phosphorylation; GO:0043549|regulation of kinase activity; GO:0050727|regulation of inflammatory response	GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0016020|membrane	GO:0036312|phosphatidylinositol 3-kinase regulatory subunit binding; GO:0042802|identical protein binding	"ko:K12230|PIK3AP1,BCAP"	ko04151|PI3K-Akt signaling pathway; ko04662|B cell receptor signaling pathway	3070	NP_989681.1	NP_989681.1 phosphoinositide 3-kinase adapter protein 1 [Gallus gallus]	sp|Q9DDT2|BCAP_CHICK	sp|Q9DDT2|BCAP_CHICK Phosphoinositide 3-kinase adapter protein 1 OS=Gallus gallus GN=PIK3AP1 PE=1 SV=1	9031.ENSGALP00000008883	Phosphoinositide 3-kinase adapter protein 1 (B-cell phosphoinositide 3-kinase adapter protei [...] 	_	_	NOG70048	"PF14545.3|DBB|Dof, BCAP, and BANK (DBB) motif,|ENSGALT00000088192|m.4763:16-154"
ENSGALG00000005589	4.011961204	1.333226789	1.582196257	0.00296019	0.00575881	up	yes	4.864965969	1.710816874	5.460100769	1.554595438	1.519959929	0.925124999	14	6572269	6596578	+	SYNGR3	protein_coding	GO:0021762|substantia nigra development; GO:0032411|positive regulation of transporter activity; GO:0045055|regulated exocytosis	GO:0008021|synaptic vesicle; GO:0016021|integral component of membrane; GO:0030054|cell junction; GO:0030672|synaptic vesicle membrane; GO:0031594|neuromuscular junction; GO:0045202|synapse	GO:0042169|SH2 domain binding; GO:0047485|protein N-terminus binding	--	--	3194	NP_001007835.1	NP_001007835.1 synaptogyrin-3 [Gallus gallus]	sp|Q8R191|SNG3_MOUSE	sp|Q8R191|SNG3_MOUSE Synaptogyrin-3 OS=Mus musculus GN=Syngr3 PE=1 SV=1	9031.ENSGALP00000008955	synaptogyrin 3 	_	KOG4016	_	PF01284.20|MARVEL|Membrane-associating domain|ENSGALT00000008969|m.9529:39-184
ENSGALG00000005601	3.732107987	13.08137852	-1.806693924	1.13E-80	9.39E-79	down	yes	3.822082055	3.536537824	3.837704083	11.20373117	14.93762925	13.10277514	12	9048747	9114490	-	ENSGALG00000005601	protein_coding	GO:0007018|microtubule-based movement	GO:0005737|cytoplasm; GO:0005874|microtubule; GO:0005929|cilium; GO:0030286|dynein complex	GO:0003777|microtubule motor activity; GO:0005524|ATP binding; GO:0016887|ATPase activity	ko:K10408|DNAH	ko05016|Huntington's disease	11787	XP_015148869.1	"XP_015148869.1 dynein heavy chain 12, axonemal isoform X1 [Gallus gallus]"	sp|Q6ZR08|DYH12_HUMAN	"sp|Q6ZR08|DYH12_HUMAN Dynein heavy chain 12, axonemal OS=Homo sapiens GN=DNAH12 PE=2 SV=2"	9031.ENSGALP00000008972	"dynein, axonemal, heavy chain 12"	COG5245	KOG3595	_	"PF03028.12|Dynein_heavy|Dynein heavy chain and region D6 of dynein motor|ENSGALT00000008986|m.7628:3231-3924;PF08393.10|DHC_N2|Dynein heavy chain, N-terminal region 2|ENSGALT00000008986|m.7628:644-1087;PF12774.4|AAA_6|Hydrolytic ATP binding site of dynein motor region D1|ENSGALT00000008986|m.7628:1216-1443;PF12781.4|AAA_9|ATP-binding dynein motor region D5|ENSGALT00000008986|m.7628:2868-3092;PF12780.4|AAA_8|P-loop containing dynein motor region D4|ENSGALT00000008986|m.7628:2215-2484;PF12775.4|AAA_7|P-loop containing dynein motor region D3|ENSGALT00000008986|m.7628:1854-2122;PF12777.4|MT|Microtubule-binding stalk of dynein motor|ENSGALT00000008986|m.7628:2499-2840;PF07728.11|AAA_5|AAA domain (dynein-related subfamily)|ENSGALT00000008986|m.7628:1531-1673"
ENSGALG00000005673	9.681315771	32.90576637	-1.764014332	1.99E-95	2.22E-93	down	yes	8.870874885	10.75629765	9.416774774	33.4752727	33.13739059	32.10463583	10	11034282	11039009	+	DTWD1	protein_coding	--	--	--	--	--	2541	XP_015147498.1	XP_015147498.1 DTW domain-containing protein 1 isoform X1 [Gallus gallus]	sp|Q8N5C7|DTWD1_HUMAN	sp|Q8N5C7|DTWD1_HUMAN DTW domain-containing protein 1 OS=Homo sapiens GN=DTWD1 PE=1 SV=1	9031.ENSGALP00000009081	DTW domain containing 1	_	KOG3795	_	PF03942.12|DTW|DTW domain|ENSGALT00000095031|m.5548:71-296
ENSGALG00000005683	10.03595484	22.93522342	-1.19157916	1.54E-63	8.40E-62	down	yes	9.436771212	10.12350969	10.54758362	22.24136407	23.62181822	22.94248798	8	13997576	14048208	+	ARHGAP29	protein_coding	GO:0035556|intracellular signal transduction	GO:0005622|intracellular	GO:0005096|GTPase activator activity; GO:0046872|metal ion binding	ko:K20644|ARHGAP29_45	--	5310	NP_001231811.1	NP_001231811.1 rho GTPase-activating protein 29 [Gallus gallus]	sp|Q6PCS4|RHG29_DANRE	sp|Q6PCS4|RHG29_DANRE Rho GTPase-activating protein 29 OS=Danio rerio GN=arhgap29 PE=2 SV=1	9031.ENSGALP00000009099	Rho GTPase activating protein 29	_	KOG1453	_	PF00620.24|RhoGAP|RhoGAP domain|ENSGALT00000044091|m.7447:754-925;PF00130.19|C1_1|Phorbol esters/diacylglycerol binding domain (C1 domain)|ENSGALT00000044091|m.7447:685-728
ENSGALG00000005685	1.246209208	2.566466023	-1.036316818	7.38E-05	0.000184473	down	yes	1.235701613	1.443965384	1.058960626	1.960904207	2.023587499	3.714906364	19	9302652	9331188	+	ENSGALG00000005685	protein_coding	GO:0000165|MAPK cascade; GO:0006468|protein phosphorylation; GO:0007265|Ras protein signal transduction; GO:0019933|cAMP-mediated signaling; GO:0043410|positive regulation of MAPK cascade	GO:0005783|endoplasmic reticulum; GO:0005789|endoplasmic reticulum membrane; GO:0005829|cytosol; GO:0016020|membrane; GO:0032587|ruffle membrane; GO:0032991|protein-containing complex	GO:0004672|protein kinase activity; GO:0005078|MAP-kinase scaffold activity; GO:0005524|ATP binding; GO:0008022|protein C-terminus binding; GO:0046872|metal ion binding	ko:K14958|KSR1	ko04014|Ras signaling pathway; ko05152|Tuberculosis	2729	XP_004946837.1	XP_004946837.1 kinase suppressor of Ras 1 isoform X2 [Gallus gallus]	sp|Q8IVT5|KSR1_HUMAN	sp|Q8IVT5|KSR1_HUMAN Kinase suppressor of Ras 1 OS=Homo sapiens GN=KSR1 PE=1 SV=3	9031.ENSGALP00000009104	kinase suppressor of ras 1	COG0515	KOG0193	_	PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000009118|m.14207:254-517;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000009118|m.14207:257-515
ENSGALG00000005696	1.427249982	7.300034956	-2.346567293	3.83E-40	9.63E-39	down	yes	1.703425336	1.333341648	1.244982961	6.329475658	8.066173864	7.504455345	12	9340653	9350933	+	ABHD6	protein_coding	GO:0009395|phospholipid catabolic process; GO:0030336|negative regulation of cell migration; GO:0046464|acylglycerol catabolic process; GO:0046889|positive regulation of lipid biosynthetic process; GO:0060292|long-term synaptic depression; GO:2000124|regulation of endocannabinoid signaling pathway	GO:0005739|mitochondrion; GO:0016021|integral component of membrane; GO:0032281|AMPA glutamate receptor complex; GO:0070062|extracellular exosome	GO:0004620|phospholipase activity; GO:0047372|acylglycerol lipase activity	ko:K13700|ABHD6	ko04723|Retrograde endocannabinoid signaling	2289	XP_414352.1	XP_414352.1 monoacylglycerol lipase ABHD6 [Gallus gallus]	sp|Q5XI64|ABHD6_RAT	sp|Q5XI64|ABHD6_RAT Monoacylglycerol lipase ABHD6 OS=Rattus norvegicus GN=Abhd6 PE=1 SV=1	9031.ENSGALP00000009124	abhydrolase domain containing 6	COG0596	KOG1454	_	"PF00561.17|Abhydrolase_1|alpha/beta hydrolase fold|ENSGALT00000009138|m.7650:135-241;PF12697.4|Abhydrolase_6|Alpha/beta hydrolase family|ENSGALT00000009138|m.7650:137-381;PF12146.5|Hydrolase_4|Serine aminopeptidase, S33|ENSGALT00000009138|m.7650:135-375"
ENSGALG00000005757	21.99966187	48.97350784	-1.154159111	2.14E-44	6.47E-43	down	yes	20.65600371	24.10802522	21.23495668	49.14518766	52.17916515	45.5961707	11	17590414	17597150	-	IRF8	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006351|transcription, DNA-templated; GO:0006909|phagocytosis; GO:0030099|myeloid cell differentiation; GO:0032729|positive regulation of interferon-gamma production; GO:0032735|positive regulation of interleukin-12 production; GO:0042742|defense response to bacterium; GO:0042832|defense response to protozoan; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0060261|positive regulation of transcription initiation from RNA polymerase II promoter; GO:0071222|cellular response to lipopolysaccharide; GO:0071346|cellular response to interferon-gamma"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0001227|DNA-binding transcription repressor activity, RNA polymerase II-specific"	ko:K10155|IRF8	ko05133|Pertussis	2306	NP_990747.1	NP_990747.1 interferon regulatory factor 8 [Gallus gallus]	sp|Q90871|IRF8_CHICK	sp|Q90871|IRF8_CHICK Interferon regulatory factor 8 OS=Gallus gallus GN=IRF8 PE=2 SV=1	9031.ENSGALP00000009229	Interferon regulatory factor 8 (IRF-8)(Interferon consensus sequence-binding protein)(ICSBP) [...] 	_	_	NOG42878	PF10401.6|IRF-3|Interferon-regulatory factor 3|ENSGALT00000009243|m.6792:206-383;PF00605.14|IRF|Interferon regulatory factor transcription factor|ENSGALT00000009243|m.6792:9-113
ENSGALG00000005795	4.192184644	12.69273293	-1.595927459	7.37E-31	1.21E-29	down	yes	3.65910341	4.346229633	4.571220889	11.2219636	14.65492744	12.20130776	6	18406321	18414396	-	CYP2C23b	protein_coding	GO:0019373|epoxygenase P450 pathway	GO:0005623|cell; GO:0005789|endoplasmic reticulum membrane; GO:0031090|organelle membrane	GO:0005506|iron ion binding; GO:0008392|arachidonic acid epoxygenase activity; GO:0008395|steroid hydroxylase activity; GO:0020037|heme binding; GO:0070330|aromatase activity	ko:K17853|CYP2H	--	2160	NP_001001757.1	NP_001001757.1 cytochrome P450 2H2 precursor [Gallus gallus]	sp|P20678|CP2H2_CHICK	sp|P20678|CP2H2_CHICK Cytochrome P450 2H2 OS=Gallus gallus GN=CYP2H2 PE=1 SV=1	_	_	_	_	_	PF00067.19|p450|Cytochrome P450|ENSGALT00000009308|m.4799:33-487
ENSGALG00000005802	0.298464623	0.788164441	-1.371580968	6.42E-10	2.82E-09	down	yes	0.293692415	0.347473247	0.254228207	0.770792363	0.823639415	0.770061544	13	14053033	14099309	+	FLT4	protein_coding	GO:0001525|angiogenesis; GO:0030154|cell differentiation; GO:0038084|vascular endothelial growth factor signaling pathway; GO:0046777|protein autophosphorylation; GO:0048010|vascular endothelial growth factor receptor signaling pathway	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005887|integral component of plasma membrane	GO:0005524|ATP binding; GO:0036328|VEGF-C-activated receptor activity; GO:0042803|protein homodimerization activity	"ko:K05097|FLT4,VEGFR3"	ko04014|Ras signaling pathway; ko04015|Rap1 signaling pathway; ko04060|Cytokine-cytokine receptor interaction; ko04151|PI3K-Akt signaling pathway; ko04510|Focal adhesion; ko05224|Breast cancer	7894	NP_001280022.1	NP_001280022.1 vascular endothelial growth factor receptor 3 precursor [Gallus gallus]	sp|P79701|VGFR3_COTCO	sp|P79701|VGFR3_COTCO Vascular endothelial growth factor receptor 3 OS=Coturnix coturnix GN=FLT4 PE=2 SV=1	9031.ENSGALP00000009174	Tyrosine kinase VEGFR-3 Fragment 	COG0515	KOG0200	_	PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000009188|m.8902:893-1216;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000009188|m.8902:280-360;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000009188|m.8902:389-448;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000009188|m.8902:609-705;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000009188|m.8902:729-800;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000009188|m.8902:896-996;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000009188|m.8902:1053-1213;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000009188|m.8902:284-373;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000009188|m.8902:395-460;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000009188|m.8902:726-813;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000009188|m.8902:289-373;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000009188|m.8902:406-451;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000009188|m.8902:737-813;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000009188|m.8902:286-360;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000009188|m.8902:734-810
ENSGALG00000005806	1.846178059	4.77605166	-1.366500858	7.09E-18	5.78E-17	down	yes	1.296250267	2.357891924	1.884391984	4.481289742	5.052266836	4.794598402	Z	7583295	7612042	-	KIF24	protein_coding	GO:0007018|microtubule-based movement; GO:0007019|microtubule depolymerization; GO:0060271|cilium assembly; GO:0097711|ciliary basal body-plasma membrane docking	GO:0005814|centriole; GO:0005829|cytosol; GO:0005871|kinesin complex; GO:0005874|microtubule; GO:0032991|protein-containing complex	GO:0003777|microtubule motor activity; GO:0005524|ATP binding; GO:0008017|microtubule binding; GO:0016887|ATPase activity; GO:0042802|identical protein binding	"ko:K10393|KIF2_24,MCAK"	--	5028	XP_424972.3	XP_424972.3 kinesin-like protein KIF24 [Gallus gallus]	sp|Q5T7B8|KIF24_HUMAN	sp|Q5T7B8|KIF24_HUMAN Kinesin-like protein KIF24 OS=Homo sapiens GN=KIF24 PE=1 SV=2	9031.ENSGALP00000009309	kinesin family member 24	COG5059	KOG0246	_	PF00225.20|Kinesin|Kinesin motor domain|ENSGALT00000044796|m.10399:231-547;PF16796.2|Microtub_bd|Microtubule binding|ENSGALT00000044796|m.10399:225-373
ENSGALG00000005842	0.38572134	1.848403871	-2.231507293	1.45E-12	8.00E-12	down	yes	0.282351261	0.477738899	0.397073859	2.230324218	1.79529218	1.519595214	4	2531208	2539175	-	GDPD2	protein_coding	GO:0006629|lipid metabolic process; GO:0045669|positive regulation of osteoblast differentiation; GO:0090527|actin filament reorganization	GO:0005737|cytoplasm; GO:0005884|actin filament; GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0030027|lamellipodium	GO:0008889|glycerophosphodiester phosphodiesterase activity; GO:0046872|metal ion binding; GO:0047394|glycerophosphoinositol inositolphosphodiesterase activity	ko:K01124|GDPD2	--	2426	XP_420208.5	XP_420208.5 glycerophosphoinositol inositolphosphodiesterase GDPD2 [Gallus gallus]	sp|Q9HCC8|GDPD2_HUMAN	sp|Q9HCC8|GDPD2_HUMAN Glycerophosphoinositol inositolphosphodiesterase GDPD2 OS=Homo sapiens GN=GDPD2 PE=2 SV=1	9031.ENSGALP00000009370	glycerophosphodiester phosphodiesterase domain containing 2	COG0584	KOG2258	_	PF03009.14|GDPD|Glycerophosphoryl diester phosphodiesterase family|ENSGALT00000050305|m.16204:232-373
ENSGALG00000005848	0.712422691	1.569819918	-1.128845003	0.001124729	0.002350416	down	yes	0.640770962	1.102255515	0.394241597	1.835496831	1.608258639	1.265704283	Z	8328565	8349086	+	IL11RA	protein_coding	GO:0032502|developmental process; GO:0060322|head development	GO:0016021|integral component of membrane	GO:0004896|cytokine receptor activity	ko:K05056|IL11RA	ko04060|Cytokine-cytokine receptor interaction; ko04630|Jak-STAT signaling pathway; ko04640|Hematopoietic cell lineage	1838	XP_015132847.1	XP_015132847.1 interleukin-11 receptor subunit alpha isoform X3 [Gallus gallus]	sp|Q5RF19|I11RA_PONAB	sp|Q5RF19|I11RA_PONAB Interleukin-11 receptor subunit alpha OS=Pongo abelii GN=IL11RA PE=2 SV=1	59729.ENSTGUP00000001807	Interleukin-11 receptor alpha chain Precursor (IL-11R-alpha)(IL-11RA) [Taeniopygia guttata]	_	_	NOG28915	_
ENSGALG00000005884	15.63038716	45.82480694	-1.551167371	4.83E-121	1.12E-118	down	yes	15.56975016	15.60464149	15.71676983	44.37879877	48.00383249	45.09178955	2	4797808	4866093	-	MAPKKK3L	protein_coding	GO:0000165|MAPK cascade; GO:0001568|blood vessel development; GO:0007346|regulation of mitotic cell cycle; GO:0031098|stress-activated protein kinase signaling cascade; GO:0032147|activation of protein kinase activity; GO:0035556|intracellular signal transduction; GO:0042981|regulation of apoptotic process; GO:0043123|positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0046777|protein autophosphorylation; GO:1900745|positive regulation of p38MAPK cascade	GO:0005737|cytoplasm; GO:0005829|cytosol	GO:0004672|protein kinase activity; GO:0004674|protein serine/threonine kinase activity; GO:0004709|MAP kinase kinase kinase activity; GO:0005524|ATP binding; GO:0046872|metal ion binding	"ko:K04421|MAP3K3,MEKK3"	ko04010|MAPK signaling pathway; ko04722|Neurotrophin signaling pathway; ko04912|GnRH signaling pathway; ko05166|HTLV-I infection	3726	NP_001073194.1	NP_001073194.1 mitogen-activated protein kinase kinase kinase 3-like [Gallus gallus]	sp|Q99759|M3K3_HUMAN	sp|Q99759|M3K3_HUMAN Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens GN=MAP3K3 PE=1 SV=2	9031.ENSGALP00000009443	"PREDICTED: Gallus gallus hypothetical LOC420419 (LOC420419), mRNA"	COG0515	KOG0198	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000009457|m.14679:359-617;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000009457|m.14679:359-612;PF00564.21|PB1|PB1 domain|ENSGALT00000009457|m.14679:42-118
ENSGALG00000005886	1.048374943	2.655195834	-1.332390732	1.41E-10	6.62E-10	down	yes	0.924060145	1.037905584	1.183159102	2.773272999	2.558236869	2.634077635	19	9783481	9807365	+	WSCD1	protein_coding	--	GO:0016021|integral component of membrane	GO:0008146|sulfotransferase activity	--	--	2680	XP_425416.2	XP_425416.2 WSC domain-containing protein 1 isoform X1 [Gallus gallus]	sp|Q658N2|WSCD1_HUMAN	sp|Q658N2|WSCD1_HUMAN WSC domain-containing protein 1 OS=Homo sapiens GN=WSCD1 PE=2 SV=1	_	_	_	_	_	PF01822.16|WSC|WSC domain|ENSGALT00000009462|m.14253:140-219;PF01822.16|WSC|WSC domain|ENSGALT00000009462|m.14253:243-314;PF00685.24|Sulfotransfer_1|Sulfotransferase domain|ENSGALT00000009462|m.14253:422-518
ENSGALG00000005888	66.85377325	31.40573692	1.089737349	5.74E-76	4.21E-74	up	yes	65.48001303	67.12129442	67.96001229	31.68291528	30.45499645	32.07929904	14	6892250	6895546	-	PGP	protein_coding	GO:0006114|glycerol biosynthetic process; GO:0006650|glycerophospholipid metabolic process; GO:0045721|negative regulation of gluconeogenesis	GO:0005829|cytosol	"GO:0000121|glycerol-1-phosphatase activity; GO:0004721|phosphoprotein phosphatase activity; GO:0004725|protein tyrosine phosphatase activity; GO:0043136|glycerol-3-phosphatase activity; GO:0046872|metal ion binding; GO:0098519|nucleotide phosphatase activity, acting on free nucleotides"	"ko:K19269|PGP,PGLP"	ko00630|Glyoxylate and dicarboxylate metabolism; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko01130|Biosynthesis of antibiotics; ko01200|Carbon metabolism	2917	NP_001025809.1	NP_001025809.1 glycerol-3-phosphate phosphatase [Gallus gallus]	sp|Q5F4B1|PGP_CHICK	sp|Q5F4B1|PGP_CHICK Glycerol-3-phosphate phosphatase OS=Gallus gallus GN=PGP PE=2 SV=1	28377.ENSACAP00000013517	phosphoglycolate phosphatase	COG0647	KOG2882	_	PF13344.3|Hydrolase_6|Haloacid dehalogenase-like hydrolase|ENSGALT00000009467|m.9568:30-131;PF13242.3|Hydrolase_like|HAD-hyrolase-like|ENSGALT00000009467|m.9568:227-309;PF00702.23|Hydrolase|haloacid dehalogenase-like hydrolase|ENSGALT00000009467|m.9568:27-265
ENSGALG00000005889	2.91745923	7.829770966	-1.421162428	1.79E-33	3.37E-32	down	yes	2.687489862	2.766619356	3.298268474	7.571497263	8.32062246	7.597193175	8	14351493	14378262	-	CCDC18	protein_coding	--	--	--	--	--	3882	NP_001238963.1	NP_001238963.1 coiled-coil domain-containing protein 18 [Gallus gallus]	sp|Q640L5|CCD18_MOUSE	sp|Q640L5|CCD18_MOUSE Coiled-coil domain-containing protein 18 OS=Mus musculus GN=Ccdc18 PE=1 SV=1	9031.ENSGALP00000009454	coiled-coil domain containing 18	_	_	NOG122048	_
ENSGALG00000005905	8.697918055	4.256479184	1.029281822	1.65E-09	7.01E-09	up	yes	7.311655158	9.511295328	9.270803681	4.063295984	4.440209213	4.265932356	14	6905008	6910974	-	ZDHHC4	protein_coding	--	GO:0016021|integral component of membrane	GO:0019706|protein-cysteine S-palmitoyltransferase activity	"ko:K20003|ZDHHC4,SWF1"	--	1117	XP_015149964.1	XP_015149964.1 probable palmitoyltransferase ZDHHC4 [Gallus gallus]	sp|Q58DT3|ZDHC4_BOVIN	sp|Q58DT3|ZDHC4_BOVIN Probable palmitoyltransferase ZDHHC4 OS=Bos taurus GN=ZDHHC4 PE=2 SV=1	9031.ENSGALP00000009484	"zinc finger, DHHC-type containing 4"	COG5273	KOG1312	_	PF01529.17|zf-DHHC|DHHC palmitoyltransferase|ENSGALT00000009498|m.9571:177-322
ENSGALG00000005909	1.879053992	8.674861066	-2.200838833	1.70E-11	8.57E-11	down	yes	2.355965799	2.193919223	1.087276955	9.043042255	8.936886738	8.044654205	12	9596109	9612130	+	GATA2	protein_coding	GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0001655|urogenital system development; GO:0001709|cell fate determination; GO:0010725|regulation of primitive erythrocyte differentiation; GO:0021514|ventral spinal cord interneuron differentiation; GO:0021533|cell differentiation in hindbrain; GO:0021902|commitment of neuronal cell to specific neuron type in forebrain; GO:0021954|central nervous system neuron development; GO:0021983|pituitary gland development; GO:0030154|cell differentiation; GO:0035019|somatic stem cell population maintenance; GO:0035065|regulation of histone acetylation; GO:0035854|eosinophil fate commitment; GO:0042472|inner ear morphogenesis; GO:0045599|negative regulation of fat cell differentiation; GO:0045648|positive regulation of erythrocyte differentiation; GO:0045650|negative regulation of macrophage differentiation; GO:0045654|positive regulation of megakaryocyte differentiation; GO:0045746|negative regulation of Notch signaling pathway; GO:0045766|positive regulation of angiogenesis; GO:0048469|cell maturation; GO:0048873|homeostasis of number of cells within a tissue; GO:0060216|definitive hemopoiesis; GO:0060872|semicircular canal development; GO:0070345|negative regulation of fat cell proliferation; GO:0097154|GABAergic neuron differentiation; GO:2000178|negative regulation of neural precursor cell proliferation; GO:2000977|regulation of forebrain neuron differentiation	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005667|transcription factor complex	"GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding; GO:0000979|RNA polymerase II core promoter sequence-specific DNA binding; GO:0000980|RNA polymerase II distal enhancer sequence-specific DNA binding; GO:0001085|RNA polymerase II transcription factor binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003682|chromatin binding; GO:0008270|zinc ion binding; GO:0070742|C2H2 zinc finger domain binding"	ko:K17894|GATA2	--	2808	NP_001003797.1	NP_001003797.1 GATA-binding factor 2 [Gallus gallus]	sp|P23824|GATA2_CHICK	sp|P23824|GATA2_CHICK GATA-binding factor 2 OS=Gallus gallus GN=GATA2 PE=2 SV=1	_	_	_	_	_	PF00320.24|GATA|GATA zinc finger|ENSGALT00000030746|m.7678:417-450;PF00320.24|GATA|GATA zinc finger|ENSGALT00000030746|m.7678:471-504
ENSGALG00000005936	0.600720432	0.25141837	1.224151585	0.002921896	0.005692562	up	yes	0.468554551	0.749551863	0.58405488	0.208290663	0.252697653	0.293266795	4	2997857	3013197	+	AGTR2	protein_coding	"GO:0001974|blood vessel remodeling; GO:0001991|regulation of systemic arterial blood pressure by circulatory renin-angiotensin; GO:0002018|renin-angiotensin regulation of aldosterone production; GO:0002033|angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure; GO:0002035|brain renin-angiotensin system; GO:0006883|cellular sodium ion homeostasis; GO:0006954|inflammatory response; GO:0007166|cell surface receptor signaling pathway; GO:0007186|G protein-coupled receptor signaling pathway; GO:0007199|G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger; GO:0007263|nitric oxide mediated signal transduction; GO:0007420|brain development; GO:0008217|regulation of blood pressure; GO:0008284|positive regulation of cell population proliferation; GO:0010459|negative regulation of heart rate; GO:0010700|negative regulation of norepinephrine secretion; GO:0021695|cerebellar cortex development; GO:0030308|negative regulation of cell growth; GO:0032304|negative regulation of icosanoid secretion; GO:0032516|positive regulation of phosphoprotein phosphatase activity; GO:0035556|intracellular signal transduction; GO:0035566|regulation of metanephros size; GO:0035640|exploration behavior; GO:0035815|positive regulation of renal sodium excretion; GO:0035932|aldosterone secretion; GO:0042311|vasodilation; GO:0042416|dopamine biosynthetic process; GO:0043537|negative regulation of blood vessel endothelial cell migration; GO:0045429|positive regulation of nitric oxide biosynthetic process; GO:0045893|positive regulation of transcription, DNA-templated; GO:0048147|negative regulation of fibroblast proliferation; GO:0050715|positive regulation of cytokine secretion; GO:0051000|positive regulation of nitric-oxide synthase activity; GO:0051387|negative regulation of neurotrophin TRK receptor signaling pathway; GO:0061049|cell growth involved in cardiac muscle cell development; GO:0071549|cellular response to dexamethasone stimulus; GO:0072300|positive regulation of metanephric glomerulus development; GO:0090190|positive regulation of branching involved in ureteric bud morphogenesis; GO:2001238|positive regulation of extrinsic apoptotic signaling pathway"	GO:0005576|extracellular region; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0048471|perinuclear region of cytoplasm	GO:0004945|angiotensin type II receptor activity; GO:0008134|transcription factor binding; GO:0017046|peptide hormone binding; GO:0048019|receptor antagonist activity	ko:K04167|AGTR2	ko04080|Neuroactive ligand-receptor interaction; ko04261|Adrenergic signaling in cardiomyocytes; ko04614|Renin-angiotensin system	2224	XP_004940717.1	XP_004940717.1 type-2 angiotensin II receptor [Gallus gallus]	sp|P50052|AGTR2_HUMAN	sp|P50052|AGTR2_HUMAN Type-2 angiotensin II receptor OS=Homo sapiens GN=AGTR2 PE=1 SV=1	9031.ENSGALP00000009540	"angiotensin II receptor, type 2"	_	KOG3656	_	PF00001.18|7tm_1|7 transmembrane receptor (rhodopsin family)|ENSGALT00000099352|m.16225:61-318;PF10320.6|7TM_GPCR_Srsx|Serpentine type 7TM GPCR chemoreceptor Srsx|ENSGALT00000099352|m.16225:56-332;PF10323.6|7TM_GPCR_Srv|Serpentine type 7TM GPCR chemoreceptor Srv|ENSGALT00000099352|m.16225:94-280
ENSGALG00000005957	0.624511363	1.717824372	-1.445238673	2.34E-07	8.02E-07	down	yes	0.597277666	0.451609644	0.824646779	1.628820612	1.461618266	2.063034237	4	3042069	3056203	+	ENSGALG00000005957	protein_coding	GO:0006520|cellular amino acid metabolic process; GO:0006810|transport; GO:0006865|amino acid transport; GO:0009636|response to toxic substance	GO:0005887|integral component of plasma membrane; GO:0031526|brush border membrane; GO:0031982|vesicle; GO:0070062|extracellular exosome	GO:0005215|transporter activity; GO:0005275|amine transmembrane transporter activity; GO:0005328|neurotransmitter:sodium symporter activity	ko:K05038|SLC6A5S	--	2823	XP_003641183.1	XP_003641183.1 sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) isoform X1 [Gallus gallus]	sp|Q9JMA9|S6A14_MOUSE	sp|Q9JMA9|S6A14_MOUSE Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) OS=Mus musculus GN=Slc6a14 PE=1 SV=1	9031.ENSGALP00000009566	annotation not avaliable	COG0733	KOG3660	_	PF00209.15|SNF|Sodium:neurotransmitter symporter family|ENSGALT00000009580|m.16226:37-584
ENSGALG00000006008	7.156508429	15.2424655	-1.089700163	1.19E-14	7.71E-14	down	yes	7.176889723	6.161321702	8.131313861	15.20646151	14.46163982	16.05929516	10	11559419	11588865	-	HOMER2	protein_coding	GO:0007605|sensory perception of sound; GO:0008277|regulation of G protein-coupled receptor signaling pathway; GO:0035584|calcium-mediated signaling using intracellular calcium source; GO:0048148|behavioral response to cocaine; GO:0048875|chemical homeostasis within a tissue	GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0014069|postsynaptic density; GO:0030054|cell junction; GO:0030425|dendrite; GO:0032426|stereocilium tip; GO:0043025|neuronal cell body; GO:0045177|apical part of cell; GO:0045211|postsynaptic membrane	GO:0003779|actin binding; GO:0019904|protein domain specific binding; GO:0030160|GKAP/Homer scaffold activity; GO:0035254|glutamate receptor binding; GO:0035256|G protein-coupled glutamate receptor binding; GO:0042803|protein homodimerization activity; GO:0046982|protein heterodimerization activity	ko:K15010|HOMER	ko04068|FoxO signaling pathway; ko04724|Glutamatergic synapse	1111	XP_010715755.1	XP_010715755.1 PREDICTED: homer protein homolog 2 isoform X2 [Meleagris gallopavo]	sp|O88801|HOME2_RAT	sp|O88801|HOME2_RAT Homer protein homolog 2 OS=Rattus norvegicus GN=Homer2 PE=1 SV=1	9031.ENSGALP00000009653	homer homolog 2 (Drosophila)	_	_	NOG78582	PF00568.20|WH1|WH1 domain|ENSGALT00000101573|m.5578:1-91;PF08826.7|DMPK_coil|DMPK coiled coil domain like|ENSGALT00000101573|m.5578:272-302
ENSGALG00000006011	6.314742592	12.68889266	-1.00562403	8.15E-21	7.98E-20	down	yes	5.500552941	7.26162218	6.182052654	12.21628075	13.54008709	12.31031015	19	9953043	9974603	+	KIAA0753	protein_coding	GO:0007099|centriole replication; GO:0071539|protein localization to centrosome	GO:0005813|centrosome; GO:0005814|centriole; GO:0005829|cytosol; GO:0034451|centriolar satellite	--	--	--	3178	XP_024997791.1	XP_024997791.1 protein moonraker isoform X5 [Gallus gallus]	sp|Q2KHM9|MOONR_HUMAN	sp|Q2KHM9|MOONR_HUMAN Protein moonraker OS=Homo sapiens GN=KIAA0753 PE=1 SV=3	9031.ENSGALP00000009657	KIAA0753	_	_	NOG74655	PF15718.2|DUF4673|Domain of unknown function (DUF4673)|ENSGALT00000091052|m.14261:2-567;PF15718.2|DUF4673|Domain of unknown function (DUF4673)|ENSGALT00000091052|m.14261:564-884
ENSGALG00000006053	1.703260337	4.288385031	-1.327050327	3.39E-16	2.47E-15	down	yes	1.900387616	1.464820509	1.744572887	3.891837841	4.760110255	4.213206997	15	8308323	8317487	+	SLC2A11	protein_coding	GO:0008645|hexose transmembrane transport	GO:0005634|nucleus; GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0030054|cell junction	GO:0051119|sugar transmembrane transporter activity	"ko:K08148|SLC2A11,GLUT11"	--	3244	NP_001334638.1	"NP_001334638.1 solute carrier family 2, facilitated glucose transporter member 11 [Gallus gallus]"	sp|Q9BYW1|GTR11_HUMAN	"sp|Q9BYW1|GTR11_HUMAN Solute carrier family 2, facilitated glucose transporter member 11 OS=Homo sapiens GN=SLC2A11 PE=2 SV=1"	9031.ENSGALP00000009743	"solute carrier family 2 (facilitated glucose transporter), member 11"	COG0477	KOG0569	_	PF00083.21|Sugar_tr|Sugar (and other) transporter|ENSGALT00000009757|m.10794:20-471;PF07690.13|MFS_1|Major Facilitator Superfamily|ENSGALT00000009757|m.10794:68-388
ENSGALG00000006076	2.139443836	5.258964054	-1.293555924	2.90E-14	1.83E-13	down	yes	2.066734995	2.452650591	1.898945922	4.600276394	5.848102875	5.328512892	13	14754116	14817923	+	RASGEF1C	protein_coding	GO:0007264|small GTPase mediated signal transduction	GO:0005622|intracellular	GO:0005085|guanyl-nucleotide exchange factor activity	--	--	2473	XP_025010619.1	XP_025010619.1 ras-GEF domain-containing family member 1C isoform X1 [Gallus gallus]	sp|Q8N431|RGF1C_HUMAN	sp|Q8N431|RGF1C_HUMAN Ras-GEF domain-containing family member 1C OS=Homo sapiens GN=RASGEF1C PE=2 SV=2	9031.ENSGALP00000009792	"RasGEF domain family, member 1C"	_	KOG3541	_	PF00617.16|RasGEF|RasGEF domain|ENSGALT00000009806|m.8932:246-438;PF00618.17|RasGEF_N|RasGEF N-terminal motif|ENSGALT00000009806|m.8932:76-170
ENSGALG00000006091	0.625912979	1.620406722	-1.358330644	4.33E-05	0.000112281	down	yes	0.378489096	0.63430522	0.864944623	1.728754135	1.422065013	1.710401018	8	14942815	14955149	+	ENSGALG00000006091	protein_coding	GO:0010501|RNA secondary structure unwinding; GO:0051321|meiotic cell cycle	GO:0005730|nucleolus; GO:0005737|cytoplasm	GO:0003676|nucleic acid binding; GO:0003724|RNA helicase activity; GO:0005524|ATP binding	"ko:K15271|HFM1,MER3"	--	1949	XP_019473991.1	XP_019473991.1 PREDICTED: probable ATP-dependent DNA helicase HFM1 isoform X6 [Meleagris gallopavo]	sp|A2RUV5|HFM1_XENTR	sp|A2RUV5|HFM1_XENTR Probable ATP-dependent DNA helicase HFM1 OS=Xenopus tropicalis GN=hfm1 PE=2 SV=1	_	_	_	_	_	PF02889.13|Sec63|Sec63 Brl domain|ENSGALT00000009827|m.7506:160-207
ENSGALG00000006104	0.351757299	1.142492106	-1.671662838	4.87E-05	0.00012518	down	yes	0.298702319	0.4380176	0.318551978	0.977500125	1.015966809	1.434009385	10	12079844	12100380	+	ENSGALG00000006104	protein_coding	--	GO:0031012|extracellular matrix; GO:0043231|intracellular membrane-bounded organelle	GO:0004222|metalloendopeptidase activity; GO:0008270|zinc ion binding	--	--	1764	XP_413844.3	XP_413844.3 ADAMTS-like protein 3 isoform X1 [Gallus gallus]	sp|P82987|ATL3_HUMAN	sp|P82987|ATL3_HUMAN ADAMTS-like protein 3 OS=Homo sapiens GN=ADAMTSL3 PE=1 SV=4	_	_	_	_	_	PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000048789|m.5596:258-330;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000048789|m.5596:373-434;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000048789|m.5596:270-336;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000048789|m.5596:372-445;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000048789|m.5596:374-435;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000048789|m.5596:371-441
ENSGALG00000006160	60.72593346	27.42534123	1.146514797	1.03E-27	1.47E-26	up	yes	67.40353606	54.43762369	60.33664062	29.68658686	24.10934344	28.48009337	13	15180801	15181724	+	HNRNPA0	protein_coding	"GO:0000398|mRNA splicing, via spliceosome; GO:0006397|mRNA processing; GO:0006954|inflammatory response; GO:0016070|RNA metabolic process; GO:0032496|response to lipopolysaccharide; GO:0070935|3'-UTR-mediated mRNA stabilization"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:1990904|ribonucleoprotein complex	GO:0003723|RNA binding; GO:0017091|AU-rich element binding; GO:0019901|protein kinase binding	ko:K12894|HNRNPA0	--	924	XP_025010791.1	XP_025010791.1 heterogeneous nuclear ribonucleoprotein A0 [Gallus gallus]	sp|Q13151|ROA0_HUMAN	sp|Q13151|ROA0_HUMAN Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens GN=HNRNPA0 PE=1 SV=1	9031.ENSGALP00000009933	heterogeneous nuclear ribonucleoprotein A0	_	KOG0118	_	"PF00076.19|RRM_1|RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)|ENSGALT00000009947|m.8964:9-69;PF00076.19|RRM_1|RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)|ENSGALT00000009947|m.8964:100-157"
ENSGALG00000006172	0.553295394	1.718698433	-1.617722636	1.89E-14	1.20E-13	down	yes	0.675526783	0.511274141	0.473085258	1.618851281	1.947743628	1.589500391	5	12070315	12134884	-	ABCC8	protein_coding	GO:0001678|cellular glucose homeostasis; GO:0007565|female pregnancy; GO:0007613|memory; GO:0008542|visual learning; GO:0009268|response to pH; GO:0010043|response to zinc ion; GO:0010989|negative regulation of low-density lipoprotein particle clearance; GO:0016525|negative regulation of angiogenesis; GO:0032496|response to lipopolysaccharide; GO:0032760|positive regulation of tumor necrosis factor production; GO:0032868|response to insulin; GO:0042493|response to drug; GO:0043268|positive regulation of potassium ion transport; GO:0046676|negative regulation of insulin secretion; GO:0050768|negative regulation of neurogenesis; GO:0060253|negative regulation of glial cell proliferation; GO:0061045|negative regulation of wound healing; GO:0061855|negative regulation of neuroblast migration; GO:0071310|cellular response to organic substance; GO:1900721|positive regulation of uterine smooth muscle relaxation; GO:1903818|positive regulation of voltage-gated potassium channel activity; GO:1905075|positive regulation of tight junction disassembly; GO:1905604|negative regulation of maintenance of permeability of blood-brain barrier	GO:0005886|plasma membrane; GO:0008076|voltage-gated potassium channel complex; GO:0008282|inward rectifying potassium channel; GO:0030672|synaptic vesicle membrane; GO:0042383|sarcolemma	GO:0005267|potassium channel activity; GO:0005524|ATP binding; GO:0008281|sulfonylurea receptor activity; GO:0019905|syntaxin binding; GO:0042626|ATPase-coupled transmembrane transporter activity; GO:0044325|ion channel binding	"ko:K05032|ABCC8,SUR1"	ko02010|ABC transporters; ko04911|Insulin secretion; ko04930|Type II diabetes mellitus	4836	XP_421005.2	XP_421005.2 ATP-binding cassette sub-family C member 8 [Gallus gallus]	sp|Q09429|ABCC8_RAT	sp|Q09429|ABCC8_RAT ATP-binding cassette sub-family C member 8 OS=Rattus norvegicus GN=Abcc8 PE=1 SV=4	9031.ENSGALP00000009950	"ATP-binding cassette, sub-family C (CFTR/MRP), member 8"	COG1132	KOG0054	_	PF00664.20|ABC_membrane|ABC transporter transmembrane region|ENSGALT00000009964|m.2521:319-606;PF00664.20|ABC_membrane|ABC transporter transmembrane region|ENSGALT00000009964|m.2521:1028-1306;PF00005.24|ABC_tran|ABC transporter|ENSGALT00000009964|m.2521:709-870;PF00005.24|ABC_tran|ABC transporter|ENSGALT00000009964|m.2521:1375-1523
ENSGALG00000006202	1.274432639	2.612505524	-1.02981458	9.18E-08	3.28E-07	down	yes	1.264734931	1.240951945	1.317611042	2.71444659	2.714309966	2.408760016	14	7361816	7370915	-	SCNN1B	protein_coding	GO:0035725|sodium ion transmembrane transport; GO:0050891|multicellular organismal water homeostasis; GO:0055078|sodium ion homeostasis	GO:0005887|integral component of plasma membrane; GO:0009897|external side of plasma membrane; GO:0016324|apical plasma membrane; GO:0030659|cytoplasmic vesicle membrane; GO:0034706|sodium channel complex; GO:0070062|extracellular exosome	GO:0015280|ligand-gated sodium channel activity; GO:0050699|WW domain binding	ko:K04825|SCNN1B	ko04742|Taste transduction; ko04960|Aldosterone-regulated sodium reabsorption	2833	XP_015149983.1	XP_015149983.1 amiloride-sensitive sodium channel subunit beta isoform X2 [Gallus gallus]	sp|K7FQW8|SCNNB_PELSI	sp|K7FQW8|SCNNB_PELSI Amiloride-sensitive sodium channel subunit beta OS=Pelodiscus sinensis GN=SCNN1B PE=3 SV=1	9031.ENSGALP00000009996	"sodium channel, nonvoltage-gated 1, beta (Liddle syndrome)"	_	KOG4294	_	PF00858.21|ASC|Amiloride-sensitive sodium channel|ENSGALT00000010010|m.9629:29-557
ENSGALG00000006211	6.238331679	2.698378111	1.206041873	1.43E-19	1.31E-18	up	yes	6.163803918	6.190988595	6.360202525	2.247529074	2.904170452	2.943434808	20	10015064	10033228	-	BCL2L1	protein_coding	GO:0000910|cytokinesis; GO:0001541|ovarian follicle development; GO:0001836|release of cytochrome c from mitochondria; GO:0007093|mitotic cell cycle checkpoint; GO:0007281|germ cell development; GO:0007283|spermatogenesis; GO:0008283|cell population proliferation; GO:0008284|positive regulation of cell population proliferation; GO:0008584|male gonad development; GO:0008630|intrinsic apoptotic signaling pathway in response to DNA damage; GO:0009566|fertilization; GO:0019050|suppression by virus of host apoptotic process; GO:0034097|response to cytokine; GO:0040007|growth; GO:0043065|positive regulation of apoptotic process; GO:0043524|negative regulation of neuron apoptotic process; GO:0046898|response to cycloheximide; GO:0046902|regulation of mitochondrial membrane permeability; GO:0051402|neuron apoptotic process; GO:0051881|regulation of mitochondrial membrane potential; GO:0060154|cellular process regulating host cell cycle in response to virus; GO:0070584|mitochondrion morphogenesis; GO:0071230|cellular response to amino acid stimulus; GO:0071312|cellular response to alkaloid; GO:0071480|cellular response to gamma radiation; GO:0071839|apoptotic process in bone marrow cell; GO:0097192|extrinsic apoptotic signaling pathway in absence of ligand; GO:0097284|hepatocyte apoptotic process; GO:1900118|negative regulation of execution phase of apoptosis; GO:1902042|negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; GO:1902230|negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; GO:1903077|negative regulation of protein localization to plasma membrane; GO:2001243|negative regulation of intrinsic apoptotic signaling pathway	GO:0005741|mitochondrial outer membrane; GO:0005759|mitochondrial matrix; GO:0005783|endoplasmic reticulum; GO:0005813|centrosome; GO:0005829|cytosol; GO:0016021|integral component of membrane; GO:0030054|cell junction; GO:0030672|synaptic vesicle membrane; GO:0031965|nuclear membrane; GO:0097136|Bcl-2 family protein complex	GO:0019901|protein kinase binding; GO:0042803|protein homodimerization activity; GO:0046982|protein heterodimerization activity; GO:0051434|BH3 domain binding	"ko:K04570|BCL2L1,bcl-xL"	ko01521|EGFR tyrosine kinase inhibitor resistance; ko01524|Platinum drug resistance; ko04014|Ras signaling pathway; ko04064|NF-kappa B signaling pathway; ko04137|Mitophagy - animal; ko04140|Autophagy - animal; ko04151|PI3K-Akt signaling pathway; ko04210|Apoptosis; ko04215|Apoptosis - multiple species; ko04621|NOD-like receptor signaling pathway; ko04630|Jak-STAT signaling pathway; ko05014|Amyotrophic lateral sclerosis (ALS); ko05145|Toxoplasmosis; ko05166|HTLV-I infection; ko05200|Pathways in cancer; ko05202|Transcriptional misregulation in cancer; ko05212|Pancreatic cancer; ko05220|Chronic myeloid leukemia; ko05222|Small cell lung cancer	2416	NP_001020475.1	NP_001020475.1 bcl-2-like protein 1 [Gallus gallus]	sp|Q07816|B2CL1_CHICK	sp|Q07816|B2CL1_CHICK Bcl-2-like protein 1 OS=Gallus gallus GN=BCL2L1 PE=2 SV=2	9031.ENSGALP00000010059	Bcl-2-like protein 1 (Bcl2-L-1)(Apoptosis regulator Bcl-X); Dominant regulator of apoptotic  [...] 	_	KOG4728	_	"PF00452.16|Bcl-2|Apoptosis regulator proteins, Bcl-2 family|ENSGALT00000078202|m.3402:86-184;PF02180.14|BH4|Bcl-2 homology region 4|ENSGALT00000078202|m.3402:1-25"
ENSGALG00000006221	7.942208353	2.613673263	1.599767491	8.36E-69	5.32E-67	up	yes	8.544684074	7.472255794	7.809685191	2.480006037	2.55933284	2.801680912	9	5010321	5043013	-	KIF1A	protein_coding	GO:0008089|anterograde axonal transport; GO:0022027|interkinetic nuclear migration; GO:0098840|protein transport along microtubule	GO:0005829|cytosol; GO:0005871|kinesin complex; GO:0005874|microtubule; GO:0008021|synaptic vesicle; GO:0030425|dendrite; GO:0043025|neuronal cell body; GO:0098794|postsynapse; GO:1904115|axon cytoplasm	GO:0003774|motor activity; GO:0003777|microtubule motor activity; GO:0005524|ATP binding; GO:0008017|microtubule binding; GO:0016887|ATPase activity; GO:0042802|identical protein binding; GO:0042803|protein homodimerization activity	ko:K10392|KIF1	--	7776	XP_025009324.1	XP_025009324.1 kinesin-like protein KIF1A isoform X14 [Gallus gallus]	sp|Q12756|KIF1A_HUMAN	sp|Q12756|KIF1A_HUMAN Kinesin-like protein KIF1A OS=Homo sapiens GN=KIF1A PE=1 SV=2	13616.ENSMODP00000034712	kinesin family member 1A	COG5059	KOG0245	_	PF00225.20|Kinesin|Kinesin motor domain|ENSGALT00000093733|m.8547:11-354;PF16183.2|Kinesin_assoc|Kinesin-associated|ENSGALT00000093733|m.8547:358-524;PF12473.5|DUF3694|Kinesin protein|ENSGALT00000093733|m.8547:1244-1406;PF16796.2|Microtub_bd|Microtubule binding|ENSGALT00000093733|m.8547:6-158;PF12423.5|KIF1B|Kinesin protein 1B|ENSGALT00000093733|m.8547:814-861;PF00169.26|PH|PH domain|ENSGALT00000093733|m.8547:1690-1783;PF00498.23|FHA|FHA domain|ENSGALT00000093733|m.8547:526-596
ENSGALG00000006241	0.795579332	0.202827274	1.920343621	0.000292222	0.000668229	up	yes	0.926663023	0.773795429	0.686279543	0.242057373	0.040721315	0.325703135	9	24085087	24091634	-	ENSGALG00000006241	protein_coding	GO:0007017|microtubule-based process	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005874|microtubule; GO:0015630|microtubule cytoskeleton; GO:0036064|ciliary basal body	GO:0003924|GTPase activity; GO:0005200|structural constituent of cytoskeleton; GO:0005525|GTP binding	ko:K07374|TUBA	ko04145|Phagosome; ko04210|Apoptosis; ko04530|Tight junction; ko04540|Gap junction; ko05130|Pathogenic Escherichia coli infection	2047	XP_422851.1	XP_422851.1 tubulin alpha-3 chain [Gallus gallus]	sp|Q13748|TBA3C_HUMAN	sp|Q13748|TBA3C_HUMAN Tubulin alpha-3C/D chain OS=Homo sapiens GN=TUBA3C PE=1 SV=3	9031.ENSGALP00000016978	Tubulin alpha-1 chain Fragment ; Tubulin is the major constituent of microtubules. It binds  [...] 	COG5023	KOG1376	_	"PF00091.22|Tubulin|Tubulin/FtsZ family, GTPase domain|ENSGALT00000010094|m.9412:3-213;PF03953.14|Tubulin_C|Tubulin C-terminal domain|ENSGALT00000010094|m.9412:263-391"
ENSGALG00000006270	3.432797046	7.842343131	-1.189542081	1.31E-17	1.05E-16	down	yes	3.670254356	3.447886905	3.180249877	8.637125538	7.548175352	7.341728503	14	7379189	7388599	-	SCNN1G	protein_coding	GO:0035725|sodium ion transmembrane transport; GO:0050891|multicellular organismal water homeostasis; GO:0055078|sodium ion homeostasis	GO:0005654|nucleoplasm; GO:0005730|nucleolus; GO:0005887|integral component of plasma membrane; GO:0009897|external side of plasma membrane; GO:0016324|apical plasma membrane; GO:0034706|sodium channel complex; GO:0070062|extracellular exosome	GO:0015280|ligand-gated sodium channel activity; GO:0050699|WW domain binding	ko:K04827|SCNN1G	ko04742|Taste transduction; ko04960|Aldosterone-regulated sodium reabsorption	2297	XP_015149986.1	XP_015149986.1 amiloride-sensitive sodium channel subunit gamma [Gallus gallus]	sp|K7FSQ4|SCNNG_PELSI	sp|K7FSQ4|SCNNG_PELSI Amiloride-sensitive sodium channel subunit gamma OS=Pelodiscus sinensis GN=SCNN1G PE=3 SV=1	9031.ENSGALP00000010120	"sodium channel, nonvoltage-gated 1, gamma"	_	KOG4294	_	PF00858.21|ASC|Amiloride-sensitive sodium channel|ENSGALT00000047552|m.9630:31-549
ENSGALG00000006300	896.1057299	331.2565367	1.435692588	1.76E-104	2.42E-102	up	yes	987.6201573	849.4656684	851.2313641	325.1916014	337.3711273	331.2068813	5	12754029	12780561	+	LDHA	protein_coding	GO:0005975|carbohydrate metabolic process; GO:0006090|pyruvate metabolic process	GO:0005829|cytosol	GO:0004459|L-lactate dehydrogenase activity	"ko:K00016|LDH,ldh"	ko00010|Glycolysis / Gluconeogenesis; ko00270|Cysteine and methionine metabolism; ko00620|Pyruvate metabolism; ko00640|Propanoate metabolism; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko01120|Microbial metabolism in diverse environments; ko01130|Biosynthesis of antibiotics; ko04922|Glucagon signaling pathway	1786	XP_015142066.1	XP_015142066.1 L-lactate dehydrogenase A chain isoform X1 [Gallus gallus]	sp|P00340|LDHA_CHICK	sp|P00340|LDHA_CHICK L-lactate dehydrogenase A chain OS=Gallus gallus GN=LDHA PE=1 SV=3	9031.ENSGALP00000010167	L-lactate dehydrogenase A chain (LDH-A)(EC 1.1.1.27)	COG0039	KOG1495	_	"PF00056.20|Ldh_1_N|lactate/malate dehydrogenase, NAD binding domain|ENSGALT00000039415|m.2542:76-214;PF02866.15|Ldh_1_C|lactate/malate dehydrogenase, alpha/beta C-terminal domain|ENSGALT00000039415|m.2542:218-378"
ENSGALG00000006306	0.313125049	0.857327378	-1.424484057	0.004534557	0.008565118	down	yes	0.218069691	0.139902776	0.58140268	0.727985358	1.164317838	0.679678939	12	11080285	11103940	-	UROC1	protein_coding	GO:0006548|histidine catabolic process; GO:0019556|histidine catabolic process to glutamate and formamide; GO:0019557|histidine catabolic process to glutamate and formate	GO:0005829|cytosol	GO:0016153|urocanate hydratase activity	"ko:K01712|hutU,UROC1"	ko00340|Histidine metabolism; ko01100|Metabolic pathways	1933	XP_015148842.1	XP_015148842.1 urocanate hydratase isoform X1 [Gallus gallus]	sp|Q8VC12|HUTU_MOUSE	sp|Q8VC12|HUTU_MOUSE Urocanate hydratase OS=Mus musculus GN=Uroc1 PE=1 SV=2	9031.ENSGALP00000010182	urocanase domain containing 1	COG2987	_	_	PF01175.15|Urocanase|Urocanase|ENSGALT00000010196|m.7729:16-526
ENSGALG00000006318	0.521876903	1.670885899	-1.660057501	4.35E-09	1.77E-08	down	yes	0.439441172	0.552340541	0.573848997	1.881214532	1.597280659	1.534162506	14	7710463	7723251	+	IL21R	protein_coding	GO:0030101|natural killer cell activation	GO:0016021|integral component of membrane	GO:0001532|interleukin-21 receptor activity	"ko:K05075|IL21R,CD360"	ko04060|Cytokine-cytokine receptor interaction; ko04630|Jak-STAT signaling pathway; ko04659|Th17 cell differentiation; ko05321|Inflammatory bowel disease (IBD)	2456	XP_025010868.1	XP_025010868.1 interleukin-21 receptor isoform X1 [Gallus gallus]	sp|Q9HBE5|IL21R_HUMAN	sp|Q9HBE5|IL21R_HUMAN Interleukin-21 receptor OS=Homo sapiens GN=IL21R PE=1 SV=1	9031.ENSGALP00000010200	interleukin 21 receptor 	_	_	NOG40447	_
ENSGALG00000006320	0.569889361	5.416219111	-3.226097729	1.01E-47	3.42E-46	down	yes	0.544916839	0.677469847	0.487281399	5.748057203	5.219153402	5.281446729	15	8345049	8354558	+	ENSGALG00000006320	protein_coding	GO:0008645|hexose transmembrane transport	GO:0005634|nucleus; GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0030054|cell junction	GO:0051119|sugar transmembrane transporter activity	--	--	2224	XP_004934389.1	"XP_004934389.1 solute carrier family 2, facilitated glucose transporter member 11 [Gallus gallus]"	sp|Q9BYW1|GTR11_HUMAN	"sp|Q9BYW1|GTR11_HUMAN Solute carrier family 2, facilitated glucose transporter member 11 OS=Homo sapiens GN=SLC2A11 PE=2 SV=1"	9031.ENSGALP00000010202	hypothetical protein LOC769577	COG0477	KOG0569	_	PF00083.21|Sugar_tr|Sugar (and other) transporter|ENSGALT00000047153|m.10798:40-493;PF07690.13|MFS_1|Major Facilitator Superfamily|ENSGALT00000047153|m.10798:73-408
ENSGALG00000006376	0.102646199	0.414291006	-1.913255459	0.000232165	0.000538641	down	yes	0.169623055	0.067836966	0.070478576	0.609032502	0.335426492	0.298414024	10	12525266	12542521	+	TMC3	protein_coding	GO:0006811|ion transport	GO:0016021|integral component of membrane	--	--	--	3417	NP_001005820.1	NP_001005820.1 transmembrane channel-like protein 3 [Gallus gallus]	sp|Q5YCC7|TMC3_CHICK	sp|Q5YCC7|TMC3_CHICK Transmembrane channel-like protein 3 OS=Gallus gallus GN=Tmc3 PE=2 SV=1	9031.ENSGALP00000010288	transmembrane channel-like 3	_	_	NOG78939	PF07810.10|TMC|TMC domain|ENSGALT00000010302|m.5603:499-614
ENSGALG00000006399	60.31351471	22.05437646	1.451001511	7.57E-60	3.73E-58	up	yes	63.34771387	59.86691671	57.72591356	21.28571853	24.01963756	20.8577733	10	12666066	12667133	-	TLNRD1	protein_coding	--	--	GO:0003779|actin binding	--	--	1068	XP_003209561.1	XP_003209561.1 PREDICTED: mesoderm development candidate 1 [Meleagris gallopavo]	sp|Q9ERE8|TLRN1_MOUSE	sp|Q9ERE8|TLRN1_MOUSE Talin rod domain-containing protein 1 OS=Mus musculus GN=Tlnrd1 PE=1 SV=1	9031.ENSGALP00000010316	mesoderm development candidate 1	_	KOG4261	_	_
ENSGALG00000006413	1.648844905	7.303818767	-2.140445871	3.99E-55	1.67E-53	down	yes	1.836557352	1.602602538	1.507374825	6.523849038	8.230281111	7.157326153	10	12689664	12736649	-	CEMIP	protein_coding	GO:0007605|sensory perception of sound; GO:0010800|positive regulation of peptidyl-threonine phosphorylation; GO:0030213|hyaluronan biosynthetic process; GO:0030214|hyaluronan catabolic process; GO:0030335|positive regulation of cell migration; GO:0051281|positive regulation of release of sequestered calcium ion into cytosol; GO:0090314|positive regulation of protein targeting to membrane; GO:1900020|positive regulation of protein kinase C activity	GO:0005576|extracellular region; GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005783|endoplasmic reticulum; GO:0005886|plasma membrane; GO:0005905|clathrin-coated pit; GO:0030665|clathrin-coated vesicle membrane; GO:0045334|clathrin-coated endocytic vesicle	GO:0004415|hyalurononglucosaminidase activity; GO:0005540|hyaluronic acid binding; GO:0032050|clathrin heavy chain binding; GO:0046923|ER retention sequence binding	"ko:K19031|CEMIP,KIAA1199"	--	4074	XP_004943891.1	XP_004943891.1 cell migration-inducing and hyaluronan-binding protein isoform X1 [Gallus gallus]	sp|Q8WUJ3|CEMIP_HUMAN	sp|Q8WUJ3|CEMIP_HUMAN Cell migration-inducing and hyaluronan-binding protein OS=Homo sapiens GN=CEMIP PE=1 SV=2	9031.ENSGALP00000010338	KIAA1199	_	_	NOG81482	PF15711.2|ILEI|Interleukin-like EMT inducer|ENSGALT00000010352|m.5610:180-270;PF15711.2|ILEI|Interleukin-like EMT inducer|ENSGALT00000010352|m.5610:1241-1326;PF10162.6|G8|G8 domain|ENSGALT00000010352|m.5610:44-158;PF13330.3|Mucin2_WxxW|Mucin-2 protein WxxW repeating region|ENSGALT00000010352|m.5610:317-399;PF13330.3|Mucin2_WxxW|Mucin-2 protein WxxW repeating region|ENSGALT00000010352|m.5610:441-511
ENSGALG00000006436	0.918166527	0.251705754	1.826438026	6.74E-05	0.000169554	up	yes	0.871791679	0.7670381	1.115669801	0.222987545	0.220665871	0.311463846	9	4800305	4802155	-	AQP12A	protein_coding	--	GO:0005737|cytoplasm; GO:0016021|integral component of membrane	GO:0005215|transporter activity	ko:K09871|AQP12	--	1511	NP_001103149.1	NP_001103149.1 aquaporin 12A precursor [Gallus gallus]	sp|Q8CHJ2|AQP12_MOUSE	sp|Q8CHJ2|AQP12_MOUSE Aquaporin-12 OS=Mus musculus GN=Aqp12 PE=1 SV=1	9031.ENSGALP00000010373	aquaporin 12	_	_	NOG46671	PF00230.17|MIP|Major intrinsic protein|ENSGALT00000010387|m.8461:79-249
ENSGALG00000006460	0.23311384	1.264469773	-2.390193225	1.15E-11	5.88E-11	down	yes	0.179343394	0.32873683	0.191261297	1.538080993	1.120688577	1.13463975	20	10075293	10086559	+	TTLL9	protein_coding	GO:0006464|cellular protein modification process	GO:0005737|cytoplasm; GO:0005874|microtubule; GO:0005929|cilium	GO:0005524|ATP binding; GO:0016874|ligase activity	ko:K16603|TTLL9	--	2272	XP_015151942.1	XP_015151942.1 probable tubulin polyglutamylase TTLL9 isoform X3 [Gallus gallus]	sp|Q3SZH6|TTLL9_BOVIN	sp|Q3SZH6|TTLL9_BOVIN Probable tubulin polyglutamylase TTLL9 OS=Bos taurus GN=TTLL9 PE=2 SV=1	_	_	_	_	_	PF03133.12|TTL|Tubulin-tyrosine ligase family|ENSGALT00000094172|m.3427:1-218
ENSGALG00000006491	0.024130639	0.264195331	-3.006064694	0.000196853	0.000461859	down	yes	0	0.072391916	0	0.309488721	0.299375429	0.183721842	6	20474784	20483465	-	ANKRD1	protein_coding	GO:0006357|regulation of transcription by RNA polymerase II; GO:0007519|skeletal muscle tissue development; GO:0009791|post-embryonic development; GO:0010628|positive regulation of gene expression; GO:0010629|negative regulation of gene expression; GO:0014866|skeletal myofibril assembly; GO:0035914|skeletal muscle cell differentiation; GO:0043066|negative regulation of apoptotic process; GO:0045445|myoblast differentiation; GO:0051726|regulation of cell cycle; GO:0071363|cellular response to growth factor stimulus; GO:2000288|positive regulation of myoblast proliferation	GO:0005623|cell; GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0031674|I band	GO:0003712|transcription coregulator activity; GO:0031432|titin binding; GO:0061629|RNA polymerase II-specific DNA-binding transcription factor binding	ko:K21433|--	--	3202	NP_989736.1	NP_989736.1 ankyrin repeat domain-containing protein 1 [Gallus gallus]	sp|Q7ZT11|ANKR1_CHICK	sp|Q7ZT11|ANKR1_CHICK Ankyrin repeat domain-containing protein 1 OS=Gallus gallus GN=ANKRD1 PE=2 SV=1	9031.ENSGALP00000010477	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein); May act as a nu [...] 	COG0666	KOG0504	_	PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000010491|m.4887:126-183;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000010491|m.4887:125-216;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000010491|m.4887:186-249;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000010491|m.4887:220-282;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000010491|m.4887:188-217;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000010491|m.4887:205-256;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000010491|m.4887:238-291;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000010491|m.4887:125-172;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000010491|m.4887:187-238;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000010491|m.4887:253-297;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000010491|m.4887:154-181;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000010491|m.4887:188-217;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000010491|m.4887:221-249;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000010491|m.4887:252-282;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000010491|m.4887:153-177;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000010491|m.4887:188-213;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000010491|m.4887:221-247;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000010491|m.4887:251-279
ENSGALG00000006508	0.672011101	0.168038912	1.937602632	1.31E-06	4.12E-06	up	yes	0.727734701	0.840097934	0.448200668	0.227142712	0.104103809	0.172870214	4	4750152	4964186	-	FGF13	protein_coding	GO:0000165|MAPK cascade; GO:0001764|neuron migration; GO:0006814|sodium ion transport; GO:0007026|negative regulation of microtubule depolymerization; GO:0007612|learning; GO:0007613|memory; GO:0021766|hippocampus development; GO:0021795|cerebral cortex cell migration; GO:0045200|establishment of neuroblast polarity; GO:0046785|microtubule polymerization; GO:0048671|negative regulation of collateral sprouting; GO:0072659|protein localization to plasma membrane; GO:0098909|regulation of cardiac muscle cell action potential involved in regulation of contraction; GO:1990834|response to odorant	GO:0005576|extracellular region; GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005874|microtubule; GO:0005886|plasma membrane; GO:0014704|intercalated disc; GO:0016328|lateral plasma membrane; GO:0030175|filopodium; GO:0030424|axon; GO:0030425|dendrite; GO:0030426|growth cone; GO:0043005|neuron projection	GO:0008017|microtubule binding; GO:0008083|growth factor activity; GO:0017080|sodium channel regulator activity; GO:0030295|protein kinase activator activity; GO:0044325|ion channel binding; GO:0048487|beta-tubulin binding	ko:K04358|FGF	ko04010|MAPK signaling pathway; ko04014|Ras signaling pathway; ko04015|Rap1 signaling pathway; ko04151|PI3K-Akt signaling pathway; ko04810|Regulation of actin cytoskeleton; ko05200|Pathways in cancer; ko05218|Melanoma; ko05224|Breast cancer	2572	XP_002190404.1	XP_002190404.1 PREDICTED: fibroblast growth factor 13 isoform X1 [Taeniopygia guttata]	sp|P70377|FGF13_MOUSE	sp|P70377|FGF13_MOUSE Fibroblast growth factor 13 OS=Mus musculus GN=Fgf13 PE=1 SV=2	9031.ENSGALP00000010505	fibroblast growth factor 13 	_	KOG3885	_	PF00167.15|FGF|Fibroblast growth factor|ENSGALT00000010519|m.16300:71-195
ENSGALG00000006512	946.9767341	410.5509954	1.205747642	1.07E-75	7.75E-74	up	yes	969.6520777	917.2793101	953.9988144	398.1365223	451.5041248	382.0123391	24	3102875	3110564	+	HSPA8	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006397|mRNA processing; GO:0008380|RNA splicing; GO:0045892|negative regulation of transcription, DNA-templated"	GO:0000974|Prp19 complex; GO:0005634|nucleus; GO:0005681|spliceosomal complex; GO:0005730|nucleolus; GO:0005886|plasma membrane; GO:0042470|melanosome; GO:1990904|ribonucleoprotein complex	GO:0005524|ATP binding	ko:K03283|HSPA1_8	ko03040|Spliceosome; ko04010|MAPK signaling pathway; ko04141|Protein processing in endoplasmic reticulum; ko04144|Endocytosis; ko04213|Longevity regulating pathway - multiple species; ko04612|Antigen processing and presentation; ko04915|Estrogen signaling pathway; ko05134|Legionellosis; ko05145|Toxoplasmosis; ko05162|Measles; ko05164|Influenza A; ko05169|Epstein-Barr virus infection	2880	EOA96319.1	"EOA96319.1 Heat shock cognate 71 kDa protein, partial [Anas platyrhynchos]"	sp|P19120|HSP7C_BOVIN	sp|P19120|HSP7C_BOVIN Heat shock cognate 71 kDa protein OS=Bos taurus GN=HSPA8 PE=1 SV=2	9031.ENSGALP00000040138	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8); Chaperone. May play a role  [...] 	COG0443	KOG0101	_	PF00012.17|HSP70|Hsp70 protein|ENSGALT00000060234|m.6167:7-613;PF06723.10|MreB_Mbl|MreB/Mbl protein|ENSGALT00000060234|m.6167:138-375
ENSGALG00000006520	0.145558797	0.617028431	-2.011070881	1.49E-10	6.94E-10	down	yes	0.124250505	0.136650867	0.175775018	0.691034048	0.572137225	0.587914021	14	7970779	8020491	-	MYH11	protein_coding	GO:0006939|smooth muscle contraction; GO:0030239|myofibril assembly; GO:0030241|skeletal muscle myosin thick filament assembly; GO:0048251|elastic fiber assembly; GO:0048739|cardiac muscle fiber development	GO:0005859|muscle myosin complex; GO:0030016|myofibril; GO:0032982|myosin filament	GO:0000146|microfilament motor activity; GO:0000287|magnesium ion binding; GO:0003779|actin binding; GO:0005516|calmodulin binding; GO:0005524|ATP binding; GO:0008307|structural constituent of muscle; GO:0030898|actin-dependent ATPase activity; GO:0032027|myosin light chain binding; GO:0043531|ADP binding; GO:0045159|myosin II binding; GO:0046982|protein heterodimerization activity; GO:0051015|actin filament binding	ko:K10352|MYH	ko04530|Tight junction	5937	P10587.4	"P10587.4 RecName: Full=Myosin-11; AltName: Full=Myosin heavy chain 11; AltName: Full=Myosin heavy chain, gizzard smooth muscle"	sp|P10587|MYH11_CHICK	sp|P10587|MYH11_CHICK Myosin-11 OS=Gallus gallus GN=MYH11 PE=1 SV=4	9031.ENSGALP00000032964	"Myosin-11 (Myosin heavy chain 11)(Myosin heavy chain, gizzard smooth muscle); Muscle contraction"	COG5022	KOG0161	_	PF01576.16|Myosin_tail_1|Myosin tail|ENSGALT00000082579|m.9671:854-1933;PF00063.18|Myosin_head|Myosin head (motor domain)|ENSGALT00000082579|m.9671:86-777;PF02736.16|Myosin_N|Myosin N-terminal SH3-like domain|ENSGALT00000082579|m.9671:32-72
ENSGALG00000006521	0.432870483	1.683055588	-1.93467259	6.04E-11	2.92E-10	down	yes	0.283031813	0.680201726	0.335377911	1.5318685	1.890509245	1.626789019	5	13772652	13806760	+	TRPM5	protein_coding	GO:0050909|sensory perception of taste; GO:0070588|calcium ion transmembrane transport	GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0030425|dendrite; GO:0043025|neuronal cell body	GO:0005216|ion channel activity; GO:0005227|calcium activated cation channel activity; GO:0005244|voltage-gated ion channel activity; GO:0005267|potassium channel activity; GO:0005272|sodium channel activity	ko:K04980|TRPM5	ko04742|Taste transduction	3351	XP_003641369.2	XP_003641369.2 transient receptor potential cation channel subfamily M member 5 [Gallus gallus]	sp|Q9NZQ8|TRPM5_HUMAN	sp|Q9NZQ8|TRPM5_HUMAN Transient receptor potential cation channel subfamily M member 5 OS=Homo sapiens GN=TRPM5 PE=2 SV=1	9031.ENSGALP00000010522	annotation not avaliable	_	KOG3614	_	PF00520.28|Ion_trans|Ion transport protein|ENSGALT00000010536|m.2574:717-963
ENSGALG00000006522	2.095754377	10.26763597	-2.287099389	3.52E-35	7.08E-34	down	yes	2.774893918	1.520069552	1.992299661	10.78563697	10.73492876	9.282342186	20	10105874	10112326	+	HCK	protein_coding	GO:0002522|leukocyte migration involved in immune response; GO:0002758|innate immune response-activating signal transduction; GO:0006468|protein phosphorylation; GO:0006954|inflammatory response; GO:0007155|cell adhesion; GO:0007169|transmembrane receptor protein tyrosine kinase signaling pathway; GO:0007229|integrin-mediated signaling pathway; GO:0007498|mesoderm development; GO:0008284|positive regulation of cell population proliferation; GO:0008360|regulation of cell shape; GO:0018108|peptidyl-tyrosine phosphorylation; GO:0019221|cytokine-mediated signaling pathway; GO:0030154|cell differentiation; GO:0030838|positive regulation of actin filament polymerization; GO:0031663|lipopolysaccharide-mediated signaling pathway; GO:0038083|peptidyl-tyrosine autophosphorylation; GO:0038096|Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0043066|negative regulation of apoptotic process; GO:0043299|leukocyte degranulation; GO:0045728|respiratory burst after phagocytosis; GO:0046777|protein autophosphorylation; GO:0050690|regulation of defense response to virus by virus; GO:0050727|regulation of inflammatory response; GO:0050764|regulation of phagocytosis; GO:0051090|regulation of DNA-binding transcription factor activity; GO:0060333|interferon-gamma-mediated signaling pathway; GO:0071801|regulation of podosome assembly; GO:2000251|positive regulation of actin cytoskeleton reorganization	GO:0005654|nucleoplasm; GO:0005764|lysosome; GO:0005794|Golgi apparatus; GO:0005829|cytosol; GO:0005856|cytoskeleton; GO:0005886|plasma membrane; GO:0005901|caveola; GO:0005925|focal adhesion; GO:0030133|transport vesicle; GO:0031234|extrinsic component of cytoplasmic side of plasma membrane; GO:0042995|cell projection	GO:0001784|phosphotyrosine residue binding; GO:0004713|protein tyrosine kinase activity; GO:0004715|non-membrane spanning protein tyrosine kinase activity; GO:0005102|signaling receptor binding; GO:0005524|ATP binding	ko:K08893|HCK	ko04062|Chemokine signaling pathway; ko04666|Fc gamma R-mediated phagocytosis	1545	XP_019477882.1	XP_019477882.1 PREDICTED: tyrosine-protein kinase HCK isoform X1 [Meleagris gallopavo]	sp|P08631|HCK_HUMAN	sp|P08631|HCK_HUMAN Tyrosine-protein kinase HCK OS=Homo sapiens GN=HCK PE=1 SV=5	9031.ENSGALP00000010524	hypothetical LOC431409	COG0515	KOG0197	_	PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000098249|m.3440:249-498;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000098249|m.3440:251-495;PF00017.21|SH2|SH2 domain|ENSGALT00000098249|m.3440:132-214;PF00018.25|SH3_1|SH3 domain|ENSGALT00000098249|m.3440:73-118;PF14604.3|SH3_9|Variant SH3 domain|ENSGALT00000098249|m.3440:73-122;PF07653.14|SH3_2|Variant SH3 domain|ENSGALT00000098249|m.3440:73-122
ENSGALG00000006532	5.103108574	10.76927648	-1.07598778	1.61E-10	7.49E-10	down	yes	4.882571963	4.847789381	5.578964377	11.88031606	9.695426815	10.73208658	14	8032206	8037255	-	FOPNL	protein_coding	GO:0034453|microtubule anchoring; GO:0060271|cilium assembly	GO:0031514|motile cilium; GO:0034451|centriolar satellite; GO:0036064|ciliary basal body	--	"ko:K16535|FOPNL,FOR20"	--	1036	NP_001006170.1	NP_001006170.1 lisH domain-containing protein FOPNL [Gallus gallus]	sp|Q5ZJ24|FOPNL_CHICK	sp|Q5ZJ24|FOPNL_CHICK LisH domain-containing protein FOPNL OS=Gallus gallus GN=FOPNL PE=2 SV=1	9031.ENSGALP00000010542	LisH domain-containing protein C16orf63 homolog 	_	_	NOG41150	PF09398.7|FOP_dimer|FOP N terminal dimerisation domain|ENSGALT00000010556|m.9672:61-131
ENSGALG00000006558	2.446174511	11.0452898	-2.170251871	8.32E-70	5.40E-68	down	yes	2.101492853	2.542973384	2.694057295	10.66174194	11.69667299	10.77745448	2	9627521	9652688	+	WDR60	protein_coding	GO:0007018|microtubule-based movement; GO:0035735|intraciliary transport involved in cilium assembly; GO:0048704|embryonic skeletal system morphogenesis; GO:0060271|cilium assembly	GO:0000242|pericentriolar material; GO:0005615|extracellular space; GO:0005868|cytoplasmic dynein complex; GO:0005929|cilium; GO:0070062|extracellular exosome; GO:0097542|ciliary tip; GO:0097546|ciliary base	GO:0045503|dynein light chain binding; GO:0045504|dynein heavy chain binding	--	--	3084	XP_015137633.1	XP_015137633.1 WD repeat-containing protein 60 isoform X3 [Gallus gallus]	sp|Q8WVS4|WDR60_HUMAN	sp|Q8WVS4|WDR60_HUMAN WD repeat-containing protein 60 OS=Homo sapiens GN=WDR60 PE=1 SV=3	9031.ENSGALP00000010575	WD repeat domain 60	_	KOG1587	_	"PF00400.29|WD40|WD domain, G-beta repeat|ENSGALT00000010589|m.14780:661-696"
ENSGALG00000006563	3.010313982	12.97723613	-2.104323996	2.70E-77	2.07E-75	down	yes	3.249753446	2.933640442	2.847548059	12.64783861	13.35784721	12.92602257	1	8841295	8982974	+	SEMA3D	protein_coding	GO:0007399|nervous system development; GO:0030154|cell differentiation; GO:0050919|negative chemotaxis	GO:0005615|extracellular space	GO:0038191|neuropilin binding	ko:K06840|SEMA3	ko04360|Axon guidance	2708	OPJ77821.1	OPJ77821.1 semaphorin-3D isoform B [Patagioenas fasciata monilis]	sp|Q90663|SEM3D_CHICK	sp|Q90663|SEM3D_CHICK Semaphorin-3D OS=Gallus gallus GN=SEMA3D PE=2 SV=1	9031.ENSGALP00000010582	Semaphorin-3D Precursor (Collapsin-2)(COLL-2); Induces the collapse and paralysis of neurona [...] 	_	KOG3611	_	PF01403.16|Sema|Sema domain|ENSGALT00000010596|m.359:60-500
ENSGALG00000006597	2.775021259	5.994569313	-1.10837243	2.07E-06	6.37E-06	down	yes	1.700905332	2.765320375	3.85883807	5.619046815	6.653898656	5.710762467	9	4285878	4290793	+	DZIP1L	protein_coding	GO:0032880|regulation of protein localization; GO:0060271|cilium assembly	GO:0005814|centriole; GO:0036064|ciliary basal body	GO:0003676|nucleic acid binding; GO:0046872|metal ion binding	ko:K16470|DZIP1	--	1425	XP_422684.3	XP_422684.3 zinc finger protein DZIP1L isoform X1 [Gallus gallus]	sp|Q8IYY4|DZI1L_HUMAN	sp|Q8IYY4|DZI1L_HUMAN Zinc finger protein DZIP1L OS=Homo sapiens GN=DZIP1L PE=1 SV=2	9031.ENSGALP00000010634	hypothetical LOC424872	_	_	NOG79110	PF13815.3|Dzip-like_N|Iguana/Dzip1-like DAZ-interacting protein N-terminal|ENSGALT00000041193|m.8406:21-141
ENSGALG00000006647	5.421286104	13.67343165	-1.33306432	3.61E-18	3.02E-17	down	yes	6.538496757	4.063690765	5.661670789	13.75751325	11.78830266	15.47447903	5	14360355	14381768	+	DUSP8	protein_coding	GO:0000188|inactivation of MAPK activity; GO:0016311|dephosphorylation	GO:0005634|nucleus; GO:0005737|cytoplasm	GO:0004725|protein tyrosine phosphatase activity; GO:0016791|phosphatase activity; GO:0017017|MAP kinase tyrosine/serine/threonine phosphatase activity	"ko:K04459|DUSP,MKP"	ko04010|MAPK signaling pathway	2063	XP_001232893.1	XP_001232893.1 dual specificity protein phosphatase 8 isoform X1 [Gallus gallus]	sp|Q13202|DUS8_HUMAN	sp|Q13202|DUS8_HUMAN Dual specificity protein phosphatase 8 OS=Homo sapiens GN=DUSP8 PE=1 SV=2	9031.ENSGALP00000010737	dual specificity phosphatase 8	COG2453	KOG1716	_	"PF00782.17|DSPc|Dual specificity phosphatase, catalytic domain|ENSGALT00000010751|m.2604:168-298;PF00581.17|Rhodanese|Rhodanese-like domain|ENSGALT00000010751|m.2604:14-131"
ENSGALG00000006670	1.92293118	5.344876916	-1.470063142	3.71E-19	3.32E-18	down	yes	1.931809477	2.110153474	1.72683059	5.575900708	5.800342337	4.658387704	6	20695689	20699934	-	PPP1R3C	protein_coding	GO:0005977|glycogen metabolic process; GO:0005978|glycogen biosynthetic process; GO:0006605|protein targeting	GO:0005622|intracellular	GO:0019888|protein phosphatase regulator activity; GO:0019903|protein phosphatase binding	ko:K07189|PPP1R3	ko04910|Insulin signaling pathway; ko04931|Insulin resistance	2673	XP_423102.2	XP_423102.2 protein phosphatase 1 regulatory subunit 3C [Gallus gallus]	sp|Q7TMB3|PPR3C_MOUSE	sp|Q7TMB3|PPR3C_MOUSE Protein phosphatase 1 regulatory subunit 3C OS=Mus musculus GN=Ppp1r3c PE=1 SV=1	9031.ENSGALP00000010774	"protein phosphatase 1, regulatory (inhibitor) subunit 3C"	_	KOG3986	_	PF03370.10|CBM_21|Carbohydrate/starch-binding module (family 21)|ENSGALT00000010788|m.4895:192-296;PF16760.2|CBM53|Starch/carbohydrate-binding module (family 53)|ENSGALT00000010788|m.4895:217-296
ENSGALG00000006705	2.360362826	5.09557056	-1.106964289	6.81E-17	5.20E-16	down	yes	2.170364222	2.383464304	2.527259952	4.743627021	6.031286043	4.511798616	6	21390657	21454748	+	ENSGALG00000006705	protein_coding	GO:0001778|plasma membrane repair; GO:0007520|myoblast fusion; GO:0030947|regulation of vascular endothelial growth factor receptor signaling pathway; GO:0034605|cellular response to heat	GO:0005886|plasma membrane; GO:0005901|caveola; GO:0016021|integral component of membrane; GO:0030659|cytoplasmic vesicle membrane; GO:0031410|cytoplasmic vesicle; GO:0031965|nuclear membrane; GO:0043231|intracellular membrane-bounded organelle; GO:0070062|extracellular exosome	GO:0005543|phospholipid binding	--	--	5511	XP_025007649.1	XP_025007649.1 myoferlin isoform X1 [Gallus gallus]	sp|Q69ZN7|MYOF_MOUSE	sp|Q69ZN7|MYOF_MOUSE Myoferlin OS=Mus musculus GN=Myof PE=1 SV=2	9031.ENSGALP00000038965	"fer-1-like 3, myoferlin (C. elegans)"	_	KOG1326	_	PF00168.27|C2|C2 domain|ENSGALT00000039756|m.4919:2-98;PF00168.27|C2|C2 domain|ENSGALT00000039756|m.4919:198-284;PF00168.27|C2|C2 domain|ENSGALT00000039756|m.4919:359-472;PF00168.27|C2|C2 domain|ENSGALT00000039756|m.4919:1138-1231;PF00168.27|C2|C2 domain|ENSGALT00000039756|m.4919:1323-1396;PF00168.27|C2|C2 domain|ENSGALT00000039756|m.4919:1571-1660;PF08150.9|FerB|FerB (NUC096) domain|ENSGALT00000039756|m.4919:766-839;PF08165.8|FerA|FerA (NUC095) domain|ENSGALT00000039756|m.4919:676-739;PF08151.9|FerI|FerI (NUC094) domain|ENSGALT00000039756|m.4919:301-351
ENSGALG00000006707	0.503555486	0.117798426	2.006650088	0.000163549	0.00038855	up	yes	0.611866153	0.396856857	0.501943448	0.079668119	0.18614679	0.087580369	4	5146544	5150926	+	NOX1	protein_coding	GO:0001525|angiogenesis; GO:0003081|regulation of systemic arterial blood pressure by renin-angiotensin; GO:0006739|NADP metabolic process; GO:0006801|superoxide metabolic process; GO:0006954|inflammatory response; GO:0007165|signal transduction; GO:0008217|regulation of blood pressure; GO:0008284|positive regulation of cell population proliferation; GO:0010575|positive regulation of vascular endothelial growth factor production; GO:0016477|cell migration; GO:0030198|extracellular matrix organization; GO:0042554|superoxide anion generation; GO:0042743|hydrogen peroxide metabolic process; GO:0045726|positive regulation of integrin biosynthetic process; GO:0045730|respiratory burst; GO:0046330|positive regulation of JNK cascade; GO:0048661|positive regulation of smooth muscle cell proliferation; GO:0051454|intracellular pH elevation; GO:0055114|oxidation-reduction process; GO:0071455|cellular response to hyperoxia; GO:0072592|oxygen metabolic process; GO:1902177|positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; GO:1902600|proton transmembrane transport; GO:1990451|cellular stress response to acidic pH	GO:0005769|early endosome; GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0030054|cell junction; GO:0043020|NADPH oxidase complex; GO:0071438|invadopodium membrane	GO:0016175|superoxide-generating NADPH oxidase activity; GO:0030171|voltage-gated proton channel activity; GO:0046872|metal ion binding; GO:0048365|Rac GTPase binding; GO:0050661|NADP binding	"ko:K08008|NOX1,MOX1"	ko04380|Osteoclast differentiation; ko04933|AGE-RAGE signaling pathway in diabetic complications; ko05418|Fluid shear stress and atherosclerosis	2155	XP_015133759.1	XP_015133759.1 NADPH oxidase 1 isoform X5 [Gallus gallus]	sp|Q9Y5S8|NOX1_HUMAN	sp|Q9Y5S8|NOX1_HUMAN NADPH oxidase 1 OS=Homo sapiens GN=NOX1 PE=1 SV=2	9031.ENSGALP00000010835	NADPH oxidase 1	_	KOG0039	_	PF08030.9|NAD_binding_6|Ferric reductase NAD binding domain|ENSGALT00000096142|m.16317:407-556;PF01794.16|Ferric_reduct|Ferric reductase like transmembrane component|ENSGALT00000096142|m.16317:67-229;PF08022.9|FAD_binding_8|FAD-binding domain|ENSGALT00000096142|m.16317:307-400
ENSGALG00000006728	0.098812903	0.285383805	-1.440741089	0.007834096	0.014126157	down	yes	0.193513968	0.06080769	0.042117051	0.233967628	0.344403302	0.277780485	15	9054070	9080058	-	SLC5A1	protein_coding	GO:0001656|metanephros development; GO:0001951|intestinal D-glucose absorption; GO:0006814|sodium ion transport; GO:0050892|intestinal absorption; GO:1904659|glucose transmembrane transport	GO:0005887|integral component of plasma membrane; GO:0005903|brush border; GO:0016324|apical plasma membrane; GO:0070062|extracellular exosome	GO:0005355|glucose transmembrane transporter activity; GO:0005412|glucose:sodium symporter activity	"ko:K14158|SLC5A1,SGLT1"	ko04973|Carbohydrate digestion and absorption; ko04976|Bile secretion; ko04978|Mineral absorption	3812	NP_001280169.1	NP_001280169.1 sodium/glucose cotransporter 1 [Gallus gallus]	sp|Q8C3K6|SC5A1_MOUSE	sp|Q8C3K6|SC5A1_MOUSE Sodium/glucose cotransporter 1 OS=Mus musculus GN=Slc5a1 PE=1 SV=1	9031.ENSGALP00000010870	SGLT-1 Fragment 	COG4146	KOG2349	_	PF00474.14|SSF|Sodium:solute symporter family|ENSGALT00000010884|m.10850:43-477
ENSGALG00000006756	0.23931956	0.891008215	-1.853544187	0.00038938	0.000873375	down	yes	0.364392041	0.187020793	0.166545848	1.165055951	0.734990173	0.772978522	20	10341499	10348637	-	ENSGALG00000006756	protein_coding	GO:0019730|antimicrobial humoral response; GO:0019731|antibacterial humoral response; GO:0032715|negative regulation of interleukin-6 production; GO:0032717|negative regulation of interleukin-8 production; GO:0032720|negative regulation of tumor necrosis factor production; GO:0043031|negative regulation of macrophage activation; GO:0043312|neutrophil degranulation; GO:0050829|defense response to Gram-negative bacterium; GO:0061844|antimicrobial humoral immune response mediated by antimicrobial peptide; GO:0071222|cellular response to lipopolysaccharide	GO:0005576|extracellular region; GO:0005887|integral component of plasma membrane; GO:0010494|cytoplasmic stress granule; GO:0035578|azurophil granule lumen; GO:0035580|specific granule lumen; GO:0070062|extracellular exosome	GO:0001530|lipopolysaccharide binding	--	--	1446	XP_004947243.2	XP_004947243.2 bactericidal permeability-increasing protein isoform X2 [Gallus gallus]	sp|P17213|BPI_HUMAN	sp|P17213|BPI_HUMAN Bactericidal permeability-increasing protein OS=Homo sapiens GN=BPI PE=1 SV=4	_	_	_	_	_	"PF02886.14|LBP_BPI_CETP_C|LBP / BPI / CETP family, C-terminal domain|ENSGALT00000010917|m.3486:238-475;PF01273.22|LBP_BPI_CETP|LBP / BPI / CETP family, N-terminal domain|ENSGALT00000010917|m.3486:35-201"
ENSGALG00000006785	3.157794056	30.46419663	-3.266037737	4.85E-132	1.47E-129	down	yes	3.313467784	3.176956675	2.982957707	27.62898633	37.16953565	26.5940679	13	17591206	17597339	-	IRF1	protein_coding	"GO:0006915|apoptotic process; GO:0007050|cell cycle arrest; GO:0008285|negative regulation of cell population proliferation; GO:0032728|positive regulation of interferon-beta production; GO:0034124|regulation of MyD88-dependent toll-like receptor signaling pathway; GO:0035458|cellular response to interferon-beta; GO:0043374|CD8-positive, alpha-beta T cell differentiation; GO:0045084|positive regulation of interleukin-12 biosynthetic process; GO:0045590|negative regulation of regulatory T cell differentiation; GO:0045892|negative regulation of transcription, DNA-templated; GO:0051607|defense response to virus; GO:0060333|interferon-gamma-mediated signaling pathway; GO:0071260|cellular response to mechanical stimulus; GO:2000564|regulation of CD8-positive, alpha-beta T cell proliferation"	GO:0000790|nuclear chromatin; GO:0005737|cytoplasm	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific"	ko:K09444|IRF1	ko04917|Prolactin signaling pathway; ko05133|Pertussis; ko05160|Hepatitis C	2118	XP_015149500.1	XP_015149500.1 interferon regulatory factor 1 isoform X1 [Gallus gallus]	sp|Q90876|IRF1_CHICK	sp|Q90876|IRF1_CHICK Interferon regulatory factor 1 OS=Gallus gallus GN=IRF1 PE=2 SV=1	9031.ENSGALP00000002242	Interferon regulatory factor 1 (IRF-1); Specifically binds to the upstream regulatory region [...] 	_	_	NOG42582	PF00605.14|IRF|Interferon regulatory factor transcription factor|ENSGALT00000094481|m.9073:108-212
ENSGALG00000006796	0.594854212	1.561823866	-1.377780205	0.000110985	0.000270424	down	yes	0.765024887	0.631031526	0.388506224	1.750556579	1.689318719	1.245596301	4	5171035	5178153	-	SRPX2	protein_coding	GO:0001525|angiogenesis; GO:0042325|regulation of phosphorylation; GO:0048870|cell motility; GO:0051965|positive regulation of synapse assembly; GO:0090050|positive regulation of cell migration involved in sprouting angiogenesis; GO:0098609|cell-cell adhesion	GO:0005615|extracellular space; GO:0005737|cytoplasm; GO:0009986|cell surface; GO:0015630|microtubule cytoskeleton; GO:0030054|cell junction; GO:0060076|excitatory synapse; GO:0097060|synaptic membrane	GO:0005102|signaling receptor binding; GO:0036458|hepatocyte growth factor binding; GO:0042802|identical protein binding	ko:K19408|SRPX2	--	1416	XP_015133979.1	XP_015133979.1 sushi repeat-containing protein SRPX2 [Gallus gallus]	sp|Q5EA25|SRPX2_BOVIN	sp|Q5EA25|SRPX2_BOVIN Sushi repeat-containing protein SRPX2 OS=Bos taurus GN=SRPX2 PE=2 SV=1	9031.ENSGALP00000010977	"sushi-repeat-containing protein, X-linked 2"	_	KOG4297	_	PF13778.3|DUF4174|Domain of unknown function (DUF4174)|ENSGALT00000107253|m.16327:341-459;PF02494.13|HYR|HYR domain|ENSGALT00000107253|m.16327:183-265;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000107253|m.16327:87-119;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000107253|m.16327:128-182;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000107253|m.16327:270-325
ENSGALG00000006804	0.529072739	2.588077463	-2.268892586	3.61E-18	3.02E-17	down	yes	0.516799595	0.642512981	0.427905643	2.704601478	2.559347697	2.500283216	8	16385301	16404071	+	ODF2L	protein_coding	--	GO:0005813|centrosome	--	--	--	2253	XP_025008738.1	XP_025008738.1 outer dense fiber protein 2-like isoform X4 [Gallus gallus]	sp|Q9ULJ1|ODF2L_HUMAN	sp|Q9ULJ1|ODF2L_HUMAN Outer dense fiber protein 2-like OS=Homo sapiens GN=ODF2L PE=2 SV=2	9031.ENSGALP00000038048	outer dense fiber of sperm tails 2-like	_	_	NOG146747	_
ENSGALG00000006807	0.570308687	2.95920567	-2.355184598	1.77E-18	1.52E-17	down	yes	0.561629826	0.449222701	0.700073534	3.293673737	2.695759957	2.888183316	9	11740248	11751391	-	PLSCR5	protein_coding	--	GO:0005886|plasma membrane	GO:0017128|phospholipid scramblase activity	--	--	1788	XP_004943368.2	XP_004943368.2 phospholipid scramblase family member 5 isoform X1 [Gallus gallus]	sp|A0PG75|PLS5_HUMAN	sp|A0PG75|PLS5_HUMAN Phospholipid scramblase family member 5 OS=Homo sapiens GN=PLSCR5 PE=2 SV=2	_	_	_	_	_	PF03803.12|Scramblase|Scramblase|ENSGALT00000011010|m.8786:43-258
ENSGALG00000006851	0.38935042	0.13673096	1.444481926	0.000904291	0.00191761	up	yes	0.282663731	0.386237319	0.49915021	0.096657682	0.208340517	0.10519468	4	6565250	6989919	-	ENSGALG00000006851	protein_coding	GO:0007156|homophilic cell adhesion via plasma membrane adhesion molecules; GO:0010923|negative regulation of phosphatase activity	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0005509|calcium ion binding	ko:K16498|PCDHD1	--	3782	XP_019473708.1	XP_019473708.1 PREDICTED: protocadherin-11 X-linked isoform X1 [Meleagris gallopavo]	sp|Q6KEQ9|PC11X_PIG	sp|Q6KEQ9|PC11X_PIG Protocadherin-11 X-linked OS=Sus scrofa GN=PCDH11X PE=2 SV=1	9031.ENSGALP00000011069	Cadherin Fragment 	_	KOG3594	_	PF00028.14|Cadherin|Cadherin domain|ENSGALT00000061091|m.16348:159-270;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000061091|m.16348:285-376;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000061091|m.16348:400-486;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000061091|m.16348:504-591;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000061091|m.16348:605-693;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000061091|m.16348:718-798;PF08374.8|Protocadherin|Protocadherin|ENSGALT00000061091|m.16348:805-1026;PF08266.9|Cadherin_2|Cadherin-like|ENSGALT00000061091|m.16348:41-127
ENSGALG00000006855	13.7483628	5.71240272	1.265615867	2.31E-40	5.95E-39	up	yes	12.4261526	14.99771762	13.82121819	5.481312341	5.864159372	5.791736448	9	12619518	12636112	-	MELTF	protein_coding	GO:0006501|C-terminal protein lipidation; GO:0006826|iron ion transport; GO:0010756|positive regulation of plasminogen activation; GO:0043687|post-translational protein modification; GO:0044267|cellular protein metabolic process; GO:0055072|iron ion homeostasis; GO:0090091|positive regulation of extracellular matrix disassembly; GO:1900025|negative regulation of substrate adhesion-dependent cell spreading	GO:0005576|extracellular region; GO:0005788|endoplasmic reticulum lumen; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0009986|cell surface; GO:0046658|anchored component of plasma membrane; GO:0070062|extracellular exosome	GO:0005506|iron ion binding	"ko:K06569|MFI2,CD228"	--	3511	NP_990538.2	NP_990538.2 melanotransferrin precursor [Gallus gallus]	sp|P08582|TRFM_HUMAN	sp|P08582|TRFM_HUMAN Melanotransferrin OS=Homo sapiens GN=MELTF PE=1 SV=2	9031.ENSGALP00000032783	melanotransferrin/EOS47 	_	_	NOG87503	"PF00405.14|Transferrin|Transferrin|ENSGALT00000033424|m.8802:22-355;PF00405.14|Transferrin|Transferrin|ENSGALT00000033424|m.8802:366-704;PF12974.4|Phosphonate-bd|ABC transporter, phosphonate, periplasmic substrate-binding protein|ENSGALT00000033424|m.8802:393-511"
ENSGALG00000006864	8.587067169	19.219435	-1.161399891	5.13E-50	1.85E-48	down	yes	8.901384808	7.931213999	8.9286027	18.8218379	20.22907462	18.60739248	8	16434266	16549728	+	ENSGALG00000006864	protein_coding	GO:0002244|hematopoietic progenitor cell differentiation	GO:0005576|extracellular region; GO:0005581|collagen trimer; GO:0005788|endoplasmic reticulum lumen; GO:0031012|extracellular matrix	GO:0005201|extracellular matrix structural constituent	ko:K19721|COL5AS	ko04974|Protein digestion and absorption	5363	XP_015146330.1	XP_015146330.1 collagen alpha-1(XXIV) chain isoform X2 [Gallus gallus]	sp|Q17RW2|COOA1_HUMAN	sp|Q17RW2|COOA1_HUMAN Collagen alpha-1(XXIV) chain OS=Homo sapiens GN=COL24A1 PE=1 SV=2	9031.ENSGALP00000013825	similar to alpha 1 type XXIV collagen	_	KOG3544	_	PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000011110|m.7556:462-514;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000011110|m.7556:523-580;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000011110|m.7556:559-613;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000011110|m.7556:578-628;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000011110|m.7556:1175-1233;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000011110|m.7556:1226-1283;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000011110|m.7556:1280-1335;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000011110|m.7556:1328-1386;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000011110|m.7556:1394-1452;PF01410.15|COLFI|Fibrillar collagen C-terminal domain|ENSGALT00000011110|m.7556:1488-1565;PF01410.15|COLFI|Fibrillar collagen C-terminal domain|ENSGALT00000011110|m.7556:1574-1687
ENSGALG00000006912	2.538599685	5.181731767	-1.026511064	3.17E-13	1.85E-12	down	yes	2.500594059	2.46204496	2.653160036	5.05905161	4.902494376	5.583649315	6	21812767	21889131	+	CPEB3	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0007616|long-term memory; GO:0017148|negative regulation of translation; GO:0045727|positive regulation of translation; GO:0048167|regulation of synaptic plasticity; GO:0050955|thermoception; GO:0060213|positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; GO:0060998|regulation of dendritic spine development; GO:0060999|positive regulation of dendritic spine development; GO:0061158|3'-UTR-mediated mRNA destabilization; GO:0071230|cellular response to amino acid stimulus; GO:1900153|positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:1900248|negative regulation of cytoplasmic translational elongation; GO:1900273|positive regulation of long-term synaptic potentiation; GO:1900365|positive regulation of mRNA polyadenylation"	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0014069|postsynaptic density; GO:0030014|CCR4-NOT complex; GO:0030054|cell junction; GO:0030425|dendrite; GO:0043005|neuron projection; GO:0045202|synapse; GO:0045211|postsynaptic membrane; GO:0097440|apical dendrite; GO:1990124|messenger ribonucleoprotein complex	"GO:0000900|translation repressor activity, mRNA regulatory element binding; GO:0003723|RNA binding; GO:0003730|mRNA 3'-UTR binding; GO:0008135|translation factor activity, RNA binding; GO:0035613|RNA stem-loop binding; GO:0035925|mRNA 3'-UTR AU-rich region binding; GO:0043022|ribosome binding"	"ko:K02602|CPEB,ORB"	ko04114|Oocyte meiosis; ko04320|Dorso-ventral axis formation; ko04914|Progesterone-mediated oocyte maturation	2950	XP_018766313.1	XP_018766313.1 PREDICTED: cytoplasmic polyadenylation element-binding protein 3 isoform X1 [Serinus canaria]	sp|Q7TN99|CPEB3_MOUSE	sp|Q7TN99|CPEB3_MOUSE Cytoplasmic polyadenylation element-binding protein 3 OS=Mus musculus GN=Cpeb3 PE=1 SV=1	59729.ENSTGUP00000009273	Cytoplasmic polyadenylation element-binding protein 3 (CPE-binding protein 3)(CPE-BP3)(hCPEB [...] 	_	KOG0129	_	"PF16367.2|RRM_7|RNA recognition motif|ENSGALT00000064922|m.4942:422-511;PF16366.2|CEBP_ZZ|Cytoplasmic polyadenylation element-binding protein ZZ domain|ENSGALT00000064922|m.4942:604-666;PF00076.19|RRM_1|RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)|ENSGALT00000064922|m.4942:425-486"
ENSGALG00000006963	5.230034432	11.76752276	-1.168387924	2.41E-11	1.20E-10	down	yes	5.790229572	5.342130034	4.55774369	14.04799914	10.83940259	10.41516655	18	9480639	9489310	-	ENDOV	protein_coding	GO:0006281|DNA repair	GO:0005730|nucleolus; GO:0005737|cytoplasm	"GO:0000287|magnesium ion binding; GO:0003677|DNA binding; GO:0003727|single-stranded RNA binding; GO:0016888|endodeoxyribonuclease activity, producing 5'-phosphomonoesters; GO:0016891|endoribonuclease activity, producing 5'-phosphomonoesters"	--	--	1078	XP_015735196.1	XP_015735196.1 PREDICTED: LOW QUALITY PROTEIN: endonuclease V [Coturnix japonica]	sp|Q8C9A2|ENDOV_MOUSE	sp|Q8C9A2|ENDOV_MOUSE Endonuclease V OS=Mus musculus GN=Endov PE=1 SV=2	9031.ENSGALP00000011266	similar to hypothetical protein FLJ35220	COG1515	KOG4417	_	PF04493.11|Endonuclease_5|Endonuclease V|ENSGALT00000107708|m.13061:39-241
ENSGALG00000006966	10.07016183	3.80513331	1.401713425	2.23E-50	8.09E-49	up	yes	9.19786046	10.65482786	10.35779716	3.794159002	3.935228908	3.686012021	6	22042154	22046776	+	ZNF518A	protein_coding	"GO:0006351|transcription, DNA-templated"	GO:0005634|nucleus	"GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0003677|DNA binding; GO:0046872|metal ion binding"	--	--	4623	XP_004942218.1	XP_004942218.1 zinc finger protein 518A isoform X1 [Gallus gallus]	sp|Q6AHZ1|Z518A_HUMAN	sp|Q6AHZ1|Z518A_HUMAN Zinc finger protein 518A OS=Homo sapiens GN=ZNF518A PE=1 SV=2	_	_	_	_	_	_
ENSGALG00000006997	1.65063028	4.058521898	-1.292773845	3.82E-14	2.39E-13	down	yes	1.667319612	1.639234797	1.645336432	4.454256046	3.589336491	4.131973156	17	4358151	4436723	-	BRINP1	protein_coding	GO:0001662|behavioral fear response; GO:0007050|cell cycle arrest; GO:0007614|short-term memory; GO:0008219|cell death; GO:0035176|social behavior; GO:0035640|exploration behavior; GO:0042711|maternal behavior; GO:0045666|positive regulation of neuron differentiation; GO:0045786|negative regulation of cell cycle; GO:0045930|negative regulation of mitotic cell cycle; GO:0050768|negative regulation of neurogenesis; GO:0071300|cellular response to retinoic acid; GO:0071625|vocalization behavior	GO:0005737|cytoplasm; GO:0005783|endoplasmic reticulum; GO:0030425|dendrite; GO:0043025|neuronal cell body	--	--	--	2781	NP_989780.1	NP_989780.1 BMP/retinoic acid-inducible neural-specific protein 1 precursor [Gallus gallus]	sp|Q7ZZR3|BRNP1_CHICK	sp|Q7ZZR3|BRNP1_CHICK BMP/retinoic acid-inducible neural-specific protein 1 OS=Gallus gallus GN=BRINP1 PE=2 SV=1	9031.ENSGALP00000011314	Deleted in bladder cancer protein 1 homolog Precursor (Protein FAM5A)(BMP/retinoic acid-indu [...] 	_	_	NOG38997	PF01823.16|MACPF|MAC/Perforin domain|ENSGALT00000011328|m.11899:70-159
ENSGALG00000007014	1.639750112	0.814461244	1.000723932	0.000570583	0.001246267	up	yes	1.522416384	1.608138073	1.788695878	0.66000819	1.091962413	0.69141313	6	23205808	23212431	+	PYROXD2	protein_coding	--	--	GO:0016491|oxidoreductase activity	--	--	1785	XP_025007580.1	XP_025007580.1 pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 isoform X7 [Gallus gallus]	sp|Q5RAP5|PYRD2_PONAB	sp|Q5RAP5|PYRD2_PONAB Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 OS=Pongo abelii GN=PYROXD2 PE=2 SV=1	9031.ENSGALP00000011335	chromosome 10 open reading frame 33	COG1233	KOG4254	_	PF01593.21|Amino_oxidase|Flavin containing amine oxidoreductase|ENSGALT00000011349|m.5011:288-394;PF13450.3|NAD_binding_8|NAD(P)-binding Rossmann-like domain|ENSGALT00000011349|m.5011:53-101
ENSGALG00000007025	10.42059213	33.2074332	-1.671119536	2.30E-79	1.86E-77	down	yes	10.4052617	10.58544134	10.27107336	29.28917052	36.8371402	33.49598889	1	15633800	15729892	+	CPNE8	protein_coding	--	GO:0070062|extracellular exosome	--	--	--	3646	NP_001186389.1	NP_001186389.1 copine-8 [Gallus gallus]	sp|Q86YQ8|CPNE8_HUMAN	sp|Q86YQ8|CPNE8_HUMAN Copine-8 OS=Homo sapiens GN=CPNE8 PE=1 SV=2	_	_	_	_	_	PF07002.13|Copine|Copine|ENSGALT00000011366|m.530:387-605;PF00168.27|C2|C2 domain|ENSGALT00000011366|m.530:89-187;PF00168.27|C2|C2 domain|ENSGALT00000011366|m.530:224-320
ENSGALG00000007028	0.567475768	2.932508181	-2.349214111	2.15E-29	3.25E-28	down	yes	0.506270627	0.770949824	0.425206854	2.832077228	2.931545955	3.03390136	4	8732666	8906442	-	ENSGALG00000007028	protein_coding	GO:0009966|regulation of signal transduction	GO:0005737|cytoplasm; GO:0014069|postsynaptic density; GO:0043005|neuron projection; GO:0043025|neuronal cell body; GO:0045211|postsynaptic membrane; GO:0070062|extracellular exosome	GO:0042802|identical protein binding	"ko:K17536|CNKSR2,KSR2"	ko04013|MAPK signaling pathway - fly	3366	XP_015133995.1	XP_015133995.1 connector enhancer of kinase suppressor of ras 2-like [Gallus gallus]	sp|Q9Z1T4|CNKR2_RAT	sp|Q9Z1T4|CNKR2_RAT Connector enhancer of kinase suppressor of ras 2 OS=Rattus norvegicus GN=Cnksr2 PE=1 SV=1	9031.ENSGALP00000011357	annotation not avaliable	_	KOG1738	_	PF06663.10|DUF1170|Protein of unknown function (DUF1170)|ENSGALT00000011371|m.16365:398-575;PF10534.6|CRIC_ras_sig|Connector enhancer of kinase suppressor of ras|ENSGALT00000011371|m.16365:143-235;PF00536.27|SAM_1|SAM domain (Sterile alpha motif)|ENSGALT00000011371|m.16365:68-130;PF00169.26|PH|PH domain|ENSGALT00000011371|m.16365:671-762;PF07647.14|SAM_2|SAM domain (Sterile alpha motif)|ENSGALT00000011371|m.16365:70-131;PF00595.21|PDZ|PDZ domain (Also known as DHR or GLGF)|ENSGALT00000011371|m.16365:282-349
ENSGALG00000007042	0.413655865	1.198617542	-1.512393038	4.40E-07	1.46E-06	down	yes	0.455018041	0.467067472	0.318882084	1.211771818	1.144532702	1.239548105	18	9551560	9562020	-	CCDC40	protein_coding	GO:0001947|heart looping; GO:0003341|cilium movement; GO:0003351|epithelial cilium movement involved in extracellular fluid movement; GO:0003356|regulation of cilium beat frequency; GO:0030317|flagellated sperm motility; GO:0030324|lung development; GO:0035469|determination of pancreatic left/right asymmetry; GO:0036159|inner dynein arm assembly; GO:0044458|motile cilium assembly; GO:0060287|epithelial cilium movement involved in determination of left/right asymmetry; GO:0070286|axonemal dynein complex assembly; GO:0071907|determination of digestive tract left/right asymmetry; GO:0071910|determination of liver left/right asymmetry	GO:0005737|cytoplasm; GO:0005929|cilium; GO:0005930|axoneme	--	--	--	2895	XP_024997485.1	XP_024997485.1 coiled-coil domain-containing protein 40 [Gallus gallus]	sp|Q4G0X9|CCD40_HUMAN	sp|Q4G0X9|CCD40_HUMAN Coiled-coil domain-containing protein 40 OS=Homo sapiens GN=CCDC40 PE=2 SV=2	9031.ENSGALP00000011394	coiled-coil domain containing 40	_	_	NOG138528	PF08647.8|BRE1|BRE1 E3 ubiquitin ligase|ENSGALT00000011408|m.13073:570-668
ENSGALG00000007048	6.680280106	36.68120573	-2.455295795	3.10E-265	4.17E-262	down	yes	6.27029418	7.229543749	6.54100239	35.95549135	38.77388258	35.31424327	10	17303559	17324081	+	SYNM	protein_coding	GO:0031443|fast-twitch skeletal muscle fiber contraction; GO:0045104|intermediate filament cytoskeleton organization	GO:0005882|intermediate filament; GO:0005912|adherens junction; GO:0042383|sarcolemma; GO:0043034|costamere; GO:0045111|intermediate filament cytoskeleton; GO:0060053|neurofilament cytoskeleton	GO:0005200|structural constituent of cytoskeleton; GO:0008307|structural constituent of muscle; GO:0017166|vinculin binding; GO:0019215|intermediate filament binding	ko:K10376|DMN	--	8689	NP_990140.2	NP_990140.2 synemin [Gallus gallus]	sp|O15061|SYNEM_HUMAN	sp|O15061|SYNEM_HUMAN Synemin OS=Homo sapiens GN=SYNM PE=1 SV=2	9031.ENSGALP00000033263	desmuslin 	_	_	NOG139727	PF00038.18|Filament|Intermediate filament protein|ENSGALT00000033905|m.5720:10-311
ENSGALG00000007052	3.380223497	10.88162614	-1.683767078	6.03E-46	1.92E-44	down	yes	3.710900109	3.18107596	3.248694422	11.22928749	11.28117054	10.1344204	12	12191823	12223412	+	PXK	protein_coding	GO:0006954|inflammatory response; GO:0032780|negative regulation of ATPase activity; GO:0043271|negative regulation of ion transport; GO:0050804|modulation of chemical synaptic transmission	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005815|microtubule organizing center; GO:0005829|cytosol; GO:0005886|plasma membrane	GO:0003779|actin binding; GO:0008022|protein C-terminus binding; GO:0035091|phosphatidylinositol binding	ko:K17543|PXK	--	2162	XP_015148793.1	XP_015148793.1 PX domain-containing protein kinase-like protein isoform X1 [Gallus gallus]	sp|Q7Z7A4|PXK_HUMAN	sp|Q7Z7A4|PXK_HUMAN PX domain-containing protein kinase-like protein OS=Homo sapiens GN=PXK PE=1 SV=1	9031.ENSGALP00000011409	PX domain containing serine/threonine kinase	_	_	NOG226511	PF00787.21|PX|PX domain|ENSGALT00000101401|m.7929:30-121;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000101401|m.7929:193-307;PF02205.17|WH2|WH2 motif|ENSGALT00000101401|m.7929:545-566;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000101401|m.7929:192-305
ENSGALG00000007070	1.208119509	0.383578044	1.629934034	1.06E-06	3.37E-06	up	yes	0.901488605	1.335433686	1.387436235	0.235289233	0.545717523	0.369727378	14	9166630	9185734	+	ENSGALG00000007070	protein_coding	GO:0006501|C-terminal protein lipidation; GO:0007160|cell-matrix adhesion; GO:0007605|sensory perception of sound; GO:0019226|transmission of nerve impulse	GO:0005576|extracellular region; GO:0005886|plasma membrane; GO:0009986|cell surface; GO:0016324|apical plasma membrane; GO:0031012|extracellular matrix; GO:0031225|anchored component of membrane	--	--	--	2864	XP_004945360.1	XP_004945360.1 otoancorin isoform X1 [Gallus gallus]	sp|Q7RTW8|OTOAN_HUMAN	sp|Q7RTW8|OTOAN_HUMAN Otoancorin OS=Homo sapiens GN=OTOA PE=1 SV=1	9031.ENSGALP00000011435	otoancorin	_	_	NOG27847	PF06060.9|Mesothelin|Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)|ENSGALT00000048461|m.9726:6-477
ENSGALG00000007079	2.320917424	14.26257057	-2.614275395	2.64E-162	1.22E-159	down	yes	2.438526366	2.250325248	2.273900657	13.84964311	15.16896008	13.76910853	17	3365148	3582266	+	PAPPA	protein_coding	GO:0007565|female pregnancy; GO:0032354|response to follicle-stimulating hormone; GO:0051384|response to glucocorticoid	GO:0005576|extracellular region; GO:0005615|extracellular space	GO:0004175|endopeptidase activity; GO:0004222|metalloendopeptidase activity; GO:0008237|metallopeptidase activity; GO:0046872|metal ion binding	ko:K07762|PAPPA	--	5013	XP_415522.5	XP_415522.5 pappalysin-1 isoform X1 [Gallus gallus]	sp|Q8R4K8|PAPP1_MOUSE	sp|Q8R4K8|PAPP1_MOUSE Pappalysin-1 OS=Mus musculus GN=Pappa PE=2 SV=2	9031.ENSGALP00000011455	"pregnancy-associated plasma protein A, pappalysin 1"	_	KOG4297	_	PF13385.3|Laminin_G_3|Concanavalin A-like lectin/glucanases superfamily|ENSGALT00000011469|m.11890:138-305;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000011469|m.11890:1328-1383;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000011469|m.11890:1389-1451;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000011469|m.11890:1458-1514;PF05572.10|Peptidase_M43|Pregnancy-associated plasma protein-A|ENSGALT00000011469|m.11890:552-698;PF00066.14|Notch|LNR domain|ENSGALT00000011469|m.11890:456-480
ENSGALG00000007093	12.37705875	28.24727666	-1.189788763	6.65E-46	2.10E-44	down	yes	12.70878667	11.11950509	13.30288449	28.97486356	28.27718672	27.48977969	18	9776820	9792219	+	CYTH1	protein_coding	GO:0032012|regulation of ARF protein signal transduction	GO:0005829|cytosol; GO:0031234|extrinsic component of cytoplasmic side of plasma membrane	GO:0005086|ARF guanyl-nucleotide exchange factor activity; GO:0008289|lipid binding	ko:K18441|CYTH	ko04072|Phospholipase D signaling pathway; ko04144|Endocytosis	2897	NP_001026276.1	NP_001026276.1 cytohesin-1 [Gallus gallus]	sp|Q76MZ1|CYH1_CHLAE	sp|Q76MZ1|CYH1_CHLAE Cytohesin-1 OS=Chlorocebus aethiops GN=CYTH1 PE=2 SV=1	9606.ENSP00000354398	cytohesin 1; Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation  [...] 	COG5307	KOG0930	_	PF01369.17|Sec7|Sec7 domain|ENSGALT00000067931|m.13112:286-467;PF00169.26|PH|PH domain|ENSGALT00000067931|m.13112:485-599
ENSGALG00000007098	29.1843622	62.46631513	-1.097619572	7.30E-50	2.62E-48	down	yes	28.84858341	28.14710971	30.55739348	57.45537558	69.33700486	60.60656495	1	15477557	15560977	+	KIF21A	protein_coding	GO:0007018|microtubule-based movement	GO:0005737|cytoplasm; GO:0005871|kinesin complex; GO:0005874|microtubule; GO:0030424|axon; GO:0030425|dendrite	GO:0003777|microtubule motor activity; GO:0005524|ATP binding; GO:0008017|microtubule binding; GO:0016887|ATPase activity	ko:K10395|KIF4_21_27	--	5311	XP_015131286.1	XP_015131286.1 kinesin-like protein KIF21A isoform X7 [Gallus gallus]	sp|Q9QXL2|KI21A_MOUSE	sp|Q9QXL2|KI21A_MOUSE Kinesin-like protein KIF21A OS=Mus musculus GN=Kif21a PE=1 SV=2	9031.ENSGALP00000011479	kinesin family member 21A	COG2319;COG5059	KOG0244	_	"PF00225.20|Kinesin|Kinesin motor domain|ENSGALT00000054153|m.526:15-371;PF00400.29|WD40|WD domain, G-beta repeat|ENSGALT00000054153|m.526:1333-1368;PF00400.29|WD40|WD domain, G-beta repeat|ENSGALT00000054153|m.526:1478-1518;PF00400.29|WD40|WD domain, G-beta repeat|ENSGALT00000054153|m.526:1613-1647;PF16796.2|Microtub_bd|Microtubule binding|ENSGALT00000054153|m.526:9-159"
ENSGALG00000007112	0.634877353	1.464668309	-1.193293781	1.21E-05	3.38E-05	down	yes	0.454653465	0.881002548	0.568976045	1.325382349	1.618324054	1.450298523	10	17767527	17779753	-	LINS1	protein_coding	GO:0050890|cognition	--	--	ko:K04710|CERS	ko00600|Sphingolipid metabolism; ko01100|Metabolic pathways; ko04071|Sphingolipid signaling pathway	2906	XP_025009670.1	XP_025009670.1 protein Lines homolog 1 isoform X1 [Gallus gallus]	sp|Q8NG48|LINES_HUMAN	sp|Q8NG48|LINES_HUMAN Protein Lines homolog 1 OS=Homo sapiens GN=LINS1 PE=1 SV=2	9031.ENSGALP00000011505	lines homolog 1 (Drosophila)	_	_	NOG48095	PF14694.3|LINES_N|Lines N-terminus|ENSGALT00000099141|m.5743:188-541;PF14695.3|LINES_C|Lines C-terminus|ENSGALT00000099141|m.5743:719-752
ENSGALG00000007116	0.254080788	1.177211339	-2.168525521	1.59E-12	8.71E-12	down	yes	0.257293933	0.278007778	0.226940654	0.90158813	1.440690521	1.189355366	15	9490219	9517591	-	CABP1	protein_coding	GO:0042308|negative regulation of protein import into nucleus	GO:0000139|Golgi membrane; GO:0005886|plasma membrane	GO:0005509|calcium ion binding; GO:0008139|nuclear localization sequence binding; GO:0048306|calcium-dependent protein binding	--	--	3642	XP_015130898.1	XP_015130898.1 calcium-binding protein 1 isoform X1 [Gallus gallus]	sp|Q9JLK7|CABP1_MOUSE	sp|Q9JLK7|CABP1_MOUSE Calcium-binding protein 1 OS=Mus musculus GN=Cabp1 PE=1 SV=3	_	_	_	_	_	PF00036.29|EF-hand_1|EF hand|ENSGALT00000091288|m.10899:270-298;PF00036.29|EF-hand_1|EF hand|ENSGALT00000091288|m.10899:347-375;PF00036.29|EF-hand_1|EF hand|ENSGALT00000091288|m.10899:384-410;PF13499.3|EF-hand_7|EF-hand domain pair|ENSGALT00000091288|m.10899:269-331;PF13499.3|EF-hand_7|EF-hand domain pair|ENSGALT00000091288|m.10899:347-409;PF13405.3|EF-hand_6|EF-hand domain|ENSGALT00000091288|m.10899:270-298;PF13405.3|EF-hand_6|EF-hand domain|ENSGALT00000091288|m.10899:347-375;PF13833.3|EF-hand_8|EF-hand domain pair|ENSGALT00000091288|m.10899:320-365;PF13833.3|EF-hand_8|EF-hand domain pair|ENSGALT00000091288|m.10899:360-409;PF13202.3|EF-hand_5|EF hand|ENSGALT00000091288|m.10899:271-287;PF13202.3|EF-hand_5|EF hand|ENSGALT00000091288|m.10899:348-370;PF13202.3|EF-hand_5|EF hand|ENSGALT00000091288|m.10899:387-409
ENSGALG00000007139	0.598393167	1.78123442	-1.5578783	0.002687778	0.005275571	down	yes	1.077916384	0.185959819	0.5313033	1.383321476	2.332177357	1.628204427	12	12255792	12269886	-	FAM107A	protein_coding	GO:0001558|regulation of cell growth	GO:0005634|nucleus; GO:0016607|nuclear speck; GO:0043005|neuron projection	--	--	--	831	XP_004944702.1	XP_004944702.1 protein FAM107A isoform X1 [Gallus gallus]	sp|O95990|F107A_HUMAN	sp|O95990|F107A_HUMAN Protein FAM107A OS=Homo sapiens GN=FAM107A PE=1 SV=1	9031.ENSGALP00000011549	"family with sequence similarity 107, member A"	_	_	NOG79877	PF06625.8|DUF1151|Protein of unknown function (DUF1151)|ENSGALT00000011563|m.7939:55-164
ENSGALG00000007149	9.853643535	20.41571207	-1.050193806	2.52E-22	2.72E-21	down	yes	9.827428935	9.516670947	10.21683072	22.272413	20.42357273	18.55115048	14	9258448	9306090	+	CYTH3	protein_coding	GO:0032012|regulation of ARF protein signal transduction; GO:0045785|positive regulation of cell adhesion; GO:0048193|Golgi vesicle transport; GO:0090162|establishment of epithelial cell polarity	GO:0001726|ruffle; GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0005912|adherens junction; GO:0005923|bicellular tight junction; GO:0031234|extrinsic component of cytoplasmic side of plasma membrane	"GO:0005085|guanyl-nucleotide exchange factor activity; GO:0005086|ARF guanyl-nucleotide exchange factor activity; GO:0005547|phosphatidylinositol-3,4,5-trisphosphate binding"	ko:K18441|CYTH	ko04072|Phospholipase D signaling pathway; ko04144|Endocytosis	1408	KQL61539.1	KQL61539.1 cytohesin-3 isoform X2 [Amazona aestiva]	sp|O08967|CYH3_MOUSE	sp|O08967|CYH3_MOUSE Cytohesin-3 OS=Mus musculus GN=Cyth3 PE=1 SV=1	_	_	_	_	_	PF01369.17|Sec7|Sec7 domain|ENSGALT00000098983|m.9734:57-238;PF00169.26|PH|PH domain|ENSGALT00000098983|m.9734:256-369
ENSGALG00000007157	0.525495639	1.341510721	-1.335626227	0.000570193	0.00124564	down	yes	0.349642263	0.640895028	0.585949624	1.249414387	1.382822373	1.392295404	4	9484216	9496535	-	TENT5D	protein_coding	--	--	GO:0016779|nucleotidyltransferase activity	--	--	1507	OXB57213.1	OXB57213.1 hypothetical protein ASZ78_015952 [Callipepla squamata]	sp|Q5SSF7|FA46C_MOUSE	sp|Q5SSF7|FA46C_MOUSE Putative nucleotidyltransferase FAM46C OS=Mus musculus GN=Fam46c PE=1 SV=1	9031.ENSGALP00000011580	"family with sequence similarity 46, member D"	_	KOG3852	_	PF07984.9|NTP_transf_7|Nucleotidyltransferase|ENSGALT00000011594|m.16383:12-330
ENSGALG00000007158	1.576525358	4.095056832	-1.371531615	5.47E-05	0.000139436	down	yes	2.416540477	1.232563184	1.080472413	5.59218657	2.763314765	3.929669161	14	9342202	9344743	+	SOCS1	protein_coding	GO:0001932|regulation of protein phosphorylation; GO:0007259|receptor signaling pathway via JAK-STAT; GO:0010533|regulation of activation of Janus kinase activity; GO:0016567|protein ubiquitination; GO:0019221|cytokine-mediated signaling pathway; GO:0040008|regulation of growth; GO:0042532|negative regulation of tyrosine phosphorylation of STAT protein; GO:0045444|fat cell differentiation; GO:0045591|positive regulation of regulatory T cell differentiation; GO:0046426|negative regulation of receptor signaling pathway via JAK-STAT; GO:0046627|negative regulation of insulin receptor signaling pathway; GO:0050707|regulation of cytokine secretion; GO:0060334|regulation of interferon-gamma-mediated signaling pathway; GO:0071230|cellular response to amino acid stimulus	GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0031410|cytoplasmic vesicle; GO:0036464|cytoplasmic ribonucleoprotein granule	GO:0004860|protein kinase inhibitor activity; GO:0005159|insulin-like growth factor receptor binding; GO:0019210|kinase inhibitor activity; GO:0019901|protein kinase binding	"ko:K04694|SOCS1,JAB"	ko04120|Ubiquitin mediated proteolysis; ko04380|Osteoclast differentiation; ko04630|Jak-STAT signaling pathway; ko04910|Insulin signaling pathway; ko04917|Prolactin signaling pathway; ko04930|Type II diabetes mellitus; ko05145|Toxoplasmosis; ko05206|MicroRNAs in cancer	1003	NP_001131120.1	NP_001131120.1 suppressor of cytokine signaling 1 [Gallus gallus]	sp|O15524|SOCS1_HUMAN	sp|O15524|SOCS1_HUMAN Suppressor of cytokine signaling 1 OS=Homo sapiens GN=SOCS1 PE=1 SV=1	9031.ENSGALP00000011581	Suppressor of cytokine signaling 1 	_	KOG4566	_	PF00017.21|SH2|SH2 domain|ENSGALT00000011595|m.9737:75-150;PF07525.13|SOCS_box|SOCS box|ENSGALT00000011595|m.9737:167-201
ENSGALG00000007178	69.23200132	26.83255992	1.367125159	5.26E-76	3.90E-74	up	yes	69.21583148	71.36593278	67.1142397	23.90790428	29.09083478	27.49894069	5	16940926	16958072	+	FADS2	protein_coding	GO:0006636|unsaturated fatty acid biosynthetic process	GO:0005789|endoplasmic reticulum membrane; GO:0016021|integral component of membrane	GO:0004768|stearoyl-CoA 9-desaturase activity	ko:K10226|FADS2	ko00592|alpha-Linolenic acid metabolism; ko01040|Biosynthesis of unsaturated fatty acids; ko01110|Biosynthesis of secondary metabolites; ko01212|Fatty acid metabolism; ko03320|PPAR signaling pathway	3286	NP_001153900.1	NP_001153900.1 fatty acid desaturase 2 [Gallus gallus]	sp|A4FV48|FADS2_BOVIN	sp|A4FV48|FADS2_BOVIN Fatty acid desaturase 2 OS=Bos taurus GN=FADS2 PE=2 SV=1	9031.ENSGALP00000011607	Delta-6 fatty acid desaturase Fragment 	COG5274	KOG4232	_	PF00487.21|FA_desaturase|Fatty acid desaturase|ENSGALT00000098036|m.2689:158-416;PF00173.25|Cyt-b5|Cytochrome b5-like Heme/Steroid binding domain|ENSGALT00000098036|m.2689:22-95
ENSGALG00000007199	23.17484415	10.42953414	1.151124695	4.11E-30	6.48E-29	up	yes	19.72127452	25.3480461	24.45521182	10.91954025	9.734632045	10.63443011	15	9578709	9581330	+	TRIAP1	protein_coding	GO:0006915|apoptotic process; GO:0015914|phospholipid transport; GO:0048793|pronephros development; GO:1902166|negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	GO:0005739|mitochondrion; GO:0005758|mitochondrial intermembrane space; GO:0048471|perinuclear region of cytoplasm	--	"ko:K17968|TRIAP1,MDM35"	--	2434	NP_001264437.1	NP_001264437.1 TP53-regulated inhibitor of apoptosis 1 [Gallus gallus]	sp|A9ULB4|TRIA1_XENTR	sp|A9ULB4|TRIA1_XENTR TP53-regulated inhibitor of apoptosis 1 OS=Xenopus tropicalis GN=triap1 PE=2 SV=1	9031.ENSGALP00000011638	TP53 regulated inhibitor of apoptosis 1	_	KOG3481	_	_
ENSGALG00000007217	0.143664251	0.51271897	-1.766253945	0.000749026	0.001606976	down	yes	0.206451808	0.067275842	0.157265104	0.534966817	0.508050264	0.495139829	5	16987346	16994543	+	BEST1	protein_coding	GO:0006821|chloride transport; GO:0007601|visual perception; GO:0030321|transepithelial chloride transport; GO:0034220|ion transmembrane transport; GO:0050908|detection of light stimulus involved in visual perception; GO:0051924|regulation of calcium ion transport	GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0016020|membrane; GO:0016021|integral component of membrane; GO:0016323|basolateral plasma membrane; GO:0034707|chloride channel complex	GO:0005229|intracellular calcium activated chloride channel activity; GO:0005254|chloride channel activity; GO:0015106|bicarbonate transmembrane transporter activity; GO:0042802|identical protein binding	"ko:K13878|BEST1,VMD2"	--	2297	XP_004941545.1	XP_004941545.1 bestrophin-1 isoform X1 [Gallus gallus]	sp|O76090|BEST1_HUMAN	sp|O76090|BEST1_HUMAN Bestrophin-1 OS=Homo sapiens GN=BEST1 PE=1 SV=1	_	_	_	_	_	"PF01062.18|Bestrophin|Bestrophin, RFP-TM, chloride channel|ENSGALT00000011683|m.2695:11-318"
ENSGALG00000007248	5.14935919	16.60996919	-1.687653913	1.34E-47	4.46E-46	down	yes	5.022207108	5.040001231	5.385869231	17.8989028	16.11204544	15.81895932	10	18048568	18125749	+	ENSGALG00000007248	protein_coding	GO:0043312|neutrophil degranulation	GO:0005576|extracellular region; GO:1904813|ficolin-1-rich granule lumen	--	--	--	1719	XP_003641871.1	XP_003641871.1 pleckstrin homology domain-containing family O member 2 isoform X1 [Gallus gallus]	sp|Q8TD55|PKHO2_HUMAN	sp|Q8TD55|PKHO2_HUMAN Pleckstrin homology domain-containing family O member 2 OS=Homo sapiens GN=PLEKHO2 PE=1 SV=1	_	_	_	_	_	PF00169.26|PH|PH domain|ENSGALT00000011730|m.5767:21-118
ENSGALG00000007278	11.64222806	26.27237136	-1.173489607	1.96E-54	8.12E-53	down	yes	11.46078743	10.90479998	12.56109676	25.15468741	26.65547063	27.00695603	14	9652802	9801024	+	GRIN2A	protein_coding	GO:0001964|startle response; GO:0001975|response to amphetamine; GO:0006816|calcium ion transport; GO:0007268|chemical synaptic transmission; GO:0007611|learning or memory; GO:0007612|learning; GO:0007613|memory; GO:0007626|locomotory behavior; GO:0008104|protein localization; GO:0008542|visual learning; GO:0009611|response to wounding; GO:0019233|sensory perception of pain; GO:0022008|neurogenesis; GO:0030431|sleep; GO:0033058|directional locomotion; GO:0040011|locomotion; GO:0042177|negative regulation of protein catabolic process; GO:0042391|regulation of membrane potential; GO:0042417|dopamine metabolic process; GO:0042428|serotonin metabolic process; GO:0042493|response to drug; GO:0043065|positive regulation of apoptotic process; GO:0045471|response to ethanol; GO:0048167|regulation of synaptic plasticity; GO:0050804|modulation of chemical synaptic transmission; GO:0051930|regulation of sensory perception of pain; GO:0060078|regulation of postsynaptic membrane potential; GO:0060079|excitatory postsynaptic potential; GO:0060291|long-term synaptic potentiation; GO:0097553|calcium ion transmembrane import into cytosol; GO:1900273|positive regulation of long-term synaptic potentiation	GO:0005783|endoplasmic reticulum; GO:0008021|synaptic vesicle; GO:0009986|cell surface; GO:0014069|postsynaptic density; GO:0016020|membrane; GO:0017146|NMDA selective glutamate receptor complex; GO:0030054|cell junction; GO:0042734|presynaptic membrane; GO:0043005|neuron projection; GO:0043197|dendritic spine; GO:0045202|synapse; GO:0045211|postsynaptic membrane; GO:0098839|postsynaptic density membrane; GO:0099061|integral component of postsynaptic density membrane	GO:0004972|NMDA glutamate receptor activity; GO:0005234|extracellularly glutamate-gated ion channel activity; GO:0005261|cation channel activity; GO:0005262|calcium channel activity; GO:0008270|zinc ion binding; GO:0022849|glutamate-gated calcium ion channel activity	ko:K05209|GRIN2A	ko04014|Ras signaling pathway; ko04015|Rap1 signaling pathway; ko04020|Calcium signaling pathway; ko04024|cAMP signaling pathway; ko04080|Neuroactive ligand-receptor interaction; ko04713|Circadian entrainment; ko04720|Long-term potentiation; ko04724|Glutamatergic synapse; ko04728|Dopaminergic synapse; ko05010|Alzheimer's disease; ko05014|Amyotrophic lateral sclerosis (ALS); ko05030|Cocaine addiction; ko05031|Amphetamine addiction; ko05033|Nicotine addiction; ko05034|Alcoholism; ko05322|Systemic lupus erythematosus	4377	XP_015150065.1	"XP_015150065.1 glutamate receptor ionotropic, NMDA 2A isoform X2 [Gallus gallus]"	sp|P35436|NMDE1_MOUSE	"sp|P35436|NMDE1_MOUSE Glutamate receptor ionotropic, NMDA 2A OS=Mus musculus GN=Grin2a PE=1 SV=2"	9031.ENSGALP00000011779	"glutamate receptor, ionotropic, N-methyl D-aspartate 2A"	_	KOG1053	_	"PF10565.6|NMDAR2_C|N-methyl D-aspartate receptor 2B3 C-terminus|ENSGALT00000011793|m.9747:836-1458;PF00060.23|Lig_chan|Ligand-gated ion channel|ENSGALT00000011793|m.9747:552-825;PF10613.6|Lig_chan-Glu_bd|Ligated ion channel L-glutamate- and glycine-binding site|ENSGALT00000011793|m.9747:436-536;PF00497.17|SBP_bac_3|Bacterial extracellular solute-binding proteins, family 3|ENSGALT00000011793|m.9747:454-794;PF01094.25|ANF_receptor|Receptor family ligand binding region|ENSGALT00000011793|m.9747:73-314"
ENSGALG00000007286	9.101650747	20.20846924	-1.14988942	8.77E-06	2.49E-05	down	yes	7.588495992	11.44187437	8.274581876	25.17165586	18.40669078	17.04706109	18	9947357	9961503	-	SIRT7	protein_coding	GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0007072|positive regulation of transcription involved in exit from mitosis; GO:0009303|rRNA transcription; GO:0070932|histone H3 deacetylation	GO:0005730|nucleolus; GO:0005731|nucleolus organizer region; GO:0005737|cytoplasm	GO:0003682|chromatin binding; GO:0046872|metal ion binding; GO:0070403|NAD+ binding; GO:0097372|NAD-dependent histone deacetylase activity (H3-K18 specific)	"ko:K11417|SIRT7,SIR2L7"	--	3444	NP_001278900.1	NP_001278900.1 NAD-dependent protein deacetylase sirtuin-7 [Gallus gallus]	sp|Q0P595|SIR7_BOVIN	sp|Q0P595|SIR7_BOVIN NAD-dependent protein deacetylase sirtuin-7 OS=Bos taurus GN=SIRT7 PE=2 SV=1	59729.ENSTGUP00000003659	NAD-dependent deacetylase sirtuin-7 (EC 3.5.1.-)(SIR2-like protein 7) [Taeniopygia guttata]	COG0846	KOG1905	_	PF02146.14|SIR2|Sir2 family|ENSGALT00000031439|m.13178:108-134;PF02146.14|SIR2|Sir2 family|ENSGALT00000031439|m.13178:141-275;PF01467.23|CTP_transf_like|Cytidylyltransferase-like|ENSGALT00000031439|m.13179:66-156;PF01467.23|CTP_transf_like|Cytidylyltransferase-like|ENSGALT00000031439|m.13180:1-82
ENSGALG00000007302	5.555687529	17.07961808	-1.618488336	1.72E-64	9.73E-63	down	yes	5.74406601	5.607024381	5.315972194	18.22660354	16.47871577	16.53353492	12	13943984	14003991	+	ENSGALG00000007302	protein_coding	"GO:0000226|microtubule cytoskeleton organization; GO:0006351|transcription, DNA-templated; GO:0006997|nucleus organization; GO:0007601|visual perception; GO:0016578|histone deubiquitination; GO:0016579|protein deubiquitination; GO:0042326|negative regulation of phosphorylation; GO:0043569|negative regulation of insulin-like growth factor receptor signaling pathway; GO:0045944|positive regulation of transcription by RNA polymerase II"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005730|nucleolus; GO:0005829|cytosol; GO:0015630|microtubule cytoskeleton; GO:0016363|nuclear matrix	GO:0003682|chromatin binding; GO:0036459|thiol-dependent ubiquitinyl hydrolase activity	"ko:K11318|ATXN7,SCA7"	--	2962	XP_414415.4	XP_414415.4 ataxin-7 isoform X1 [Gallus gallus]	sp|O15265|ATX7_HUMAN	sp|O15265|ATX7_HUMAN Ataxin-7 OS=Homo sapiens GN=ATXN7 PE=1 SV=1	9031.ENSGALP00000011806	ataxin 7	_	KOG4140	_	"PF08313.9|SCA7|SCA7, zinc-binding domain|ENSGALT00000091945|m.7969:311-372"
ENSGALG00000007319	0.151916199	1.015784009	-2.663407751	1.08E-08	4.23E-08	down	yes	0.104442198	0.172298499	0.179007901	0.933036413	1.084295828	1.030019787	15	9789578	9831110	-	BICDL1	protein_coding	GO:0031175|neuron projection development; GO:0055107|Golgi to secretory granule transport	GO:0005737|cytoplasm; GO:0005813|centrosome	GO:0017137|Rab GTPase binding; GO:0034452|dynactin binding	ko:K16756|CCDC64	--	1815	XP_025011327.1	XP_025011327.1 BICD family-like cargo adapter 1 isoform X2 [Gallus gallus]	sp|A0JNT9|BICL1_MOUSE	sp|A0JNT9|BICL1_MOUSE BICD family-like cargo adapter 1 OS=Mus musculus GN=Bicdl1 PE=1 SV=1	_	_	_	_	_	PF04849.10|HAP1_N|HAP1 N-terminal conserved region|ENSGALT00000086722|m.10949:71-127
ENSGALG00000007332	2.470336749	6.141624691	-1.310431483	3.57E-21	3.59E-20	down	yes	2.59449244	2.447792053	2.368725753	6.393669447	6.209488264	5.82171636	12	14033841	14122269	-	PRICKLE2	protein_coding	GO:0001825|blastocyst formation; GO:0001830|trophectodermal cell fate commitment; GO:0030010|establishment of cell polarity; GO:0031175|neuron projection development; GO:0045197|establishment or maintenance of epithelial cell apical/basal polarity	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0016327|apicolateral plasma membrane; GO:0016328|lateral plasma membrane; GO:0031965|nuclear membrane	GO:0008270|zinc ion binding	ko:K04511|PRICKLE	ko04310|Wnt signaling pathway	2762	XP_015148774.1	XP_015148774.1 prickle-like protein 2 isoform X1 [Gallus gallus]	sp|Q80Y24|PRIC2_MOUSE	sp|Q80Y24|PRIC2_MOUSE Prickle-like protein 2 OS=Mus musculus GN=Prickle2 PE=1 SV=3	9031.ENSGALP00000011851	prickle homolog 2 (Drosophila)	_	KOG1704	_	PF06297.11|PET|PET Domain|ENSGALT00000011865|m.7978:118-202;PF00412.19|LIM|LIM domain|ENSGALT00000011865|m.7978:213-272;PF00412.19|LIM|LIM domain|ENSGALT00000011865|m.7978:278-332;PF00412.19|LIM|LIM domain|ENSGALT00000011865|m.7978:338-391
ENSGALG00000007356	2.850209729	11.74727299	-2.039360633	7.38E-09	2.95E-08	down	yes	3.404892015	1.671844017	3.473893153	11.03410183	14.08774148	10.11997566	2	15014348	15032488	+	MAP3K8	protein_coding	GO:0006468|protein phosphorylation; GO:0007049|cell cycle; GO:0007346|regulation of mitotic cell cycle; GO:0023014|signal transduction by protein phosphorylation; GO:0031098|stress-activated protein kinase signaling cascade; GO:0031295|T cell costimulation; GO:0032147|activation of protein kinase activity; GO:0042981|regulation of apoptotic process; GO:0051403|stress-activated MAPK cascade	GO:0005737|cytoplasm; GO:0005829|cytosol	GO:0000287|magnesium ion binding; GO:0004674|protein serine/threonine kinase activity; GO:0004709|MAP kinase kinase kinase activity; GO:0005524|ATP binding	"ko:K04415|MAP3K8,COT"	ko04010|MAPK signaling pathway; ko04620|Toll-like receptor signaling pathway; ko04660|T cell receptor signaling pathway; ko04668|TNF signaling pathway	2808	OXB84632.1	OXB84632.1 hypothetical protein H355_001109 [Colinus virginianus]	sp|P41279|M3K8_HUMAN	sp|P41279|M3K8_HUMAN Mitogen-activated protein kinase kinase kinase 8 OS=Homo sapiens GN=MAP3K8 PE=1 SV=2	9031.ENSGALP00000011883	mitogen-activated protein kinase kinase kinase 8	COG0515	KOG0201	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000095753|m.14897:164-405;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000095753|m.14897:163-403
ENSGALG00000007357	10.34804328	41.16895086	-1.991155582	1.40E-106	2.06E-104	down	yes	11.2145409	8.842361969	10.98722698	42.45586139	42.33332747	38.71766373	9	14938213	14954449	+	BCL6	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0000902|cell morphogenesis; GO:0001953|negative regulation of cell-matrix adhesion; GO:0002467|germinal center formation; GO:0002829|negative regulation of type 2 immune response; GO:0006351|transcription, DNA-templated; GO:0006954|inflammatory response; GO:0006974|cellular response to DNA damage stimulus; GO:0007266|Rho protein signal transduction; GO:0007283|spermatogenesis; GO:0008104|protein localization; GO:0008285|negative regulation of cell population proliferation; GO:0030036|actin cytoskeleton organization; GO:0030183|B cell differentiation; GO:0030308|negative regulation of cell growth; GO:0030890|positive regulation of B cell proliferation; GO:0032764|negative regulation of mast cell cytokine production; GO:0035024|negative regulation of Rho protein signal transduction; GO:0042092|type 2 immune response; GO:0042127|regulation of cell population proliferation; GO:0043065|positive regulation of apoptotic process; GO:0043066|negative regulation of apoptotic process; GO:0043087|regulation of GTPase activity; GO:0043380|regulation of memory T cell differentiation; GO:0045595|regulation of cell differentiation; GO:0045892|negative regulation of transcription, DNA-templated; GO:0048294|negative regulation of isotype switching to IgE isotypes; GO:0048821|erythrocyte development; GO:0050727|regulation of inflammatory response; GO:0051272|positive regulation of cellular component movement"	GO:0005634|nucleus	GO:0003682|chromatin binding; GO:0043565|sequence-specific DNA binding; GO:0046872|metal ion binding	ko:K15618|BCL6	ko04068|FoxO signaling pathway; ko05202|Transcriptional misregulation in cancer	2619	XP_015146892.1	XP_015146892.1 B-cell lymphoma 6 protein homolog isoform X1 [Gallus gallus]	sp|Q5ZM39|BCL6_CHICK	sp|Q5ZM39|BCL6_CHICK B-cell lymphoma 6 protein homolog OS=Gallus gallus GN=BCL6 PE=2 SV=1	9031.ENSGALP00000011884	B-cell lymphoma 6 protein homolog ; Transcriptional repressor which is required for germinal [...] 	COG5048	KOG1721	_	PF00651.28|BTB|BTB/POZ domain|ENSGALT00000011898|m.8914:22-128;PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000011898|m.8914:576-596;PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000011898|m.8914:634-653
ENSGALG00000007403	80.53254081	38.93954445	1.04814453	1.75E-51	6.61E-50	up	yes	78.52005435	79.0969605	83.98060758	39.93078096	38.0858994	38.80195299	15	10177078	10179073	-	PEBP1	protein_coding	--	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0070062|extracellular exosome	GO:0003723|RNA binding; GO:0004867|serine-type endopeptidase inhibitor activity; GO:0005524|ATP binding; GO:0008289|lipid binding; GO:0019901|protein kinase binding	--	--	1224	NP_001185571.1	NP_001185571.1 phosphatidylethanolamine-binding protein 1 [Gallus gallus]	sp|P13696|PEBP1_BOVIN	sp|P13696|PEBP1_BOVIN Phosphatidylethanolamine-binding protein 1 OS=Bos taurus GN=PEBP1 PE=1 SV=2	9031.ENSGALP00000011961	phosphatidylethanolamine binding protein 1	COG1881	KOG3346	_	PF01161.17|PBP|Phosphatidylethanolamine-binding protein|ENSGALT00000084750|m.10973:57-169
ENSGALG00000007426	12.12283694	49.30529288	-2.023118176	1.62E-83	1.42E-81	down	yes	11.22869901	11.40316963	13.73664218	55.28575002	45.19122451	47.43890412	2	15687491	15728548	+	MKX	protein_coding	"GO:0006355|regulation of transcription, DNA-templated; GO:0007517|muscle organ development"	GO:0005634|nucleus	GO:0043565|sequence-specific DNA binding	--	--	1572	XP_015137550.2	XP_015137550.2 homeobox protein Mohawk isoform X1 [Gallus gallus]	sp|Q8IYA7|MKX_HUMAN	sp|Q8IYA7|MKX_HUMAN Homeobox protein Mohawk OS=Homo sapiens GN=MKX PE=2 SV=2	9031.ENSGALP00000012003	mohawk homeobox	_	KOG0773	_	PF05920.8|Homeobox_KN|Homeobox KN domain|ENSGALT00000087293|m.14914:259-298;PF00046.26|Homeobox|Homeobox domain|ENSGALT00000087293|m.14914:264-300
ENSGALG00000007431	4.980870805	14.77964708	-1.567224163	3.54E-78	2.77E-76	down	yes	4.939789603	4.993773947	5.009048864	14.92909282	15.43905746	13.97079096	12	14398620	14690794	-	MAGI1	protein_coding	GO:0007155|cell adhesion; GO:0007166|cell surface receptor signaling pathway; GO:0065003|protein-containing complex assembly; GO:0070997|neuron death	GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005886|plasma membrane; GO:0005911|cell-cell junction; GO:0005912|adherens junction; GO:0005923|bicellular tight junction; GO:0030054|cell junction; GO:0042995|cell projection	GO:0005524|ATP binding; GO:0008022|protein C-terminus binding; GO:0051393|alpha-actinin binding; GO:0060090|molecular adaptor activity	"ko:K05631|AIP3,WWP3,BAIAP1"	ko04015|Rap1 signaling pathway; ko04530|Tight junction	4725	XP_015148756.1	"XP_015148756.1 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 isoform X10 [Gallus gallus]"	sp|Q96QZ7|MAGI1_HUMAN	"sp|Q96QZ7|MAGI1_HUMAN Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 OS=Homo sapiens GN=MAGI1 PE=1 SV=3"	9031.ENSGALP00000012015	annotation not avaliable	COG0194;COG5021	KOG3209	_	PF00595.21|PDZ|PDZ domain (Also known as DHR or GLGF)|ENSGALT00000095590|m.7982:456-522;PF00595.21|PDZ|PDZ domain (Also known as DHR or GLGF)|ENSGALT00000095590|m.7982:625-701;PF00595.21|PDZ|PDZ domain (Also known as DHR or GLGF)|ENSGALT00000095590|m.7982:800-874;PF00595.21|PDZ|PDZ domain (Also known as DHR or GLGF)|ENSGALT00000095590|m.7982:952-1031;PF00595.21|PDZ|PDZ domain (Also known as DHR or GLGF)|ENSGALT00000095590|m.7982:1095-1170;PF16666.2|MAGI_u5|Unstructured region on MAGI|ENSGALT00000095590|m.7982:703-793;PF16663.2|MAGI_u1|Unstructured region on MAGI|ENSGALT00000095590|m.7982:195-253;PF00397.23|WW|WW domain|ENSGALT00000095590|m.7982:297-326;PF00397.23|WW|WW domain|ENSGALT00000095590|m.7982:356-385;PF00625.18|Guanylate_kin|Guanylate kinase|ENSGALT00000095590|m.7982:131-182
ENSGALG00000007441	3.13542754	1.453687295	1.103648761	4.29E-15	2.89E-14	up	yes	3.106243244	3.320395979	2.979643396	1.321835051	1.638010466	1.401216368	1	196900378	196929712	-	MAP6	protein_coding	GO:0000226|microtubule cytoskeleton organization; GO:0006810|transport; GO:0032418|lysosome localization; GO:0048813|dendrite morphogenesis	GO:0005737|cytoplasm; GO:0005874|microtubule	GO:0005516|calmodulin binding; GO:0008017|microtubule binding	ko:K10432|MAP6	--	5038	XP_025000052.1	XP_025000052.1 microtubule-associated protein 6 homolog isoform X2 [Gallus gallus]	sp|O73737|MAP6_CHICK	sp|O73737|MAP6_CHICK Microtubule-associated protein 6 homolog OS=Gallus gallus GN=MAP6 PE=2 SV=1	_	_	_	_	_	_
ENSGALG00000007447	3.689152793	1.312234408	1.484216929	6.71E-20	6.28E-19	up	yes	3.593741056	3.575981944	3.897735379	1.364653275	1.387470704	1.184579246	20	10887341	10892358	-	TUBB1	protein_coding	GO:0051225|spindle assembly	GO:0005737|cytoplasm; GO:0005874|microtubule; GO:0070062|extracellular exosome	GO:0003924|GTPase activity; GO:0005200|structural constituent of cytoskeleton; GO:0005525|GTP binding	ko:K07375|TUBB	ko04145|Phagosome; ko04540|Gap junction; ko05130|Pathogenic Escherichia coli infection	3079	NP_990776.1	NP_990776.1 tubulin beta-6 chain [Gallus gallus]	sp|P09207|TBB6_CHICK	sp|P09207|TBB6_CHICK Tubulin beta-6 chain OS=Gallus gallus PE=1 SV=1	9031.ENSGALP00000012034	Tubulin beta-6 chain (Beta-tubulin class-VI); Tubulin is the major constituent of microtubul [...] 	COG5023	KOG1375	_	"PF00091.22|Tubulin|Tubulin/FtsZ family, GTPase domain|ENSGALT00000012048|m.3575:3-211;PF03953.14|Tubulin_C|Tubulin C-terminal domain|ENSGALT00000012048|m.3575:261-381"
ENSGALG00000007483	10.13788124	23.65271265	-1.22143693	6.65E-57	2.93E-55	down	yes	10.83747188	9.914612067	9.661559763	23.94349306	23.63759424	23.37705064	12	14847918	14926384	-	LRIG1	protein_coding	GO:0007605|sensory perception of sound; GO:0022405|hair cycle process; GO:0032474|otolith morphogenesis; GO:0060384|innervation	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	--	--	--	3768	XP_425165.5	XP_425165.5 leucine-rich repeats and immunoglobulin-like domains protein 1 isoform X2 [Gallus gallus]	sp|Q96JA1|LRIG1_HUMAN	sp|Q96JA1|LRIG1_HUMAN Leucine-rich repeats and immunoglobulin-like domains protein 1 OS=Homo sapiens GN=LRIG1 PE=1 SV=2	9031.ENSGALP00000035449	leucine-rich repeats and immunoglobulin-like domains 1	COG4886	KOG4194	_	PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000036226|m.7999:173-232;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000036226|m.7999:220-264;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000036226|m.7999:246-305;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000036226|m.7999:294-352;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000036226|m.7999:316-376;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000036226|m.7999:341-400;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000036226|m.7999:366-422;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000036226|m.7999:413-472;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000036226|m.7999:488-545;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000036226|m.7999:600-700;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000036226|m.7999:704-794;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000036226|m.7999:799-885;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000036226|m.7999:599-686;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000036226|m.7999:704-781;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000036226|m.7999:798-872;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000036226|m.7999:602-700;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000036226|m.7999:710-789;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000036226|m.7999:805-875;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000036226|m.7999:607-693;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000036226|m.7999:709-788;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000036226|m.7999:805-875;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000036226|m.7999:176-290;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000036226|m.7999:309-429;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000036226|m.7999:446-544;PF01463.21|LRRCT|Leucine rich repeat C-terminal domain|ENSGALT00000036226|m.7999:571-595
ENSGALG00000007493	63.55610282	30.60891506	1.053834477	2.91E-29	4.37E-28	up	yes	63.88031652	67.10192861	59.68606334	27.79999423	35.67825114	28.3484998	4	11273078	11283634	-	NSDHL	protein_coding	GO:0001942|hair follicle development; GO:0006695|cholesterol biosynthetic process; GO:0007224|smoothened signaling pathway; GO:0008203|cholesterol metabolic process; GO:0060716|labyrinthine layer blood vessel development	GO:0005783|endoplasmic reticulum; GO:0005789|endoplasmic reticulum membrane; GO:0005811|lipid droplet; GO:0016021|integral component of membrane	GO:0003854|3-beta-hydroxy-delta5-steroid dehydrogenase activity; GO:0047012|sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity; GO:0103066|4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-oxidoreductase (decarboxylating) activity; GO:0103067|4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-dehydrogenase (decarboxylating) activity	"ko:K07748|E1.1.1.170,NSDHL,ERG26"	ko00100|Steroid biosynthesis; ko01100|Metabolic pathways; ko01130|Biosynthesis of antibiotics	1813	XP_420279.1	"XP_420279.1 sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating [Gallus gallus]"	sp|Q9R1J0|NSDHL_MOUSE	"sp|Q9R1J0|NSDHL_MOUSE Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating OS=Mus musculus GN=Nsdhl PE=1 SV=1"	9031.ENSGALP00000031700	NAD(P) dependent steroid dehydrogenase-like	COG0451	KOG1430	_	"PF01073.16|3Beta_HSD|3-beta hydroxysteroid dehydrogenase/isomerase family|ENSGALT00000032336|m.16438:13-264;PF01370.18|Epimerase|NAD dependent epimerase/dehydratase family|ENSGALT00000032336|m.16438:13-228;PF16363.2|GDP_Man_Dehyd|GDP-mannose 4,6 dehydratase|ENSGALT00000032336|m.16438:14-232;PF13460.3|NAD_binding_10|NAD(P)H-binding|ENSGALT00000032336|m.16438:16-174;PF04321.14|RmlD_sub_bind|RmlD substrate binding domain|ENSGALT00000032336|m.16438:11-260;PF07993.9|NAD_binding_4|Male sterility protein|ENSGALT00000032336|m.16438:47-216;PF02719.12|Polysacc_synt_2|Polysaccharide biosynthesis protein|ENSGALT00000032336|m.16438:16-117;PF05368.10|NmrA|NmrA-like family|ENSGALT00000032336|m.16438:13-116"
ENSGALG00000007515	1.213760061	0.368854514	1.691604879	0.00020531	0.000480302	up	yes	1.03919606	1.693198786	0.908885338	0.506711483	0.2131102	0.386741859	6	23251548	23253727	+	SFRP5	protein_coding	GO:0008285|negative regulation of cell population proliferation; GO:0030154|cell differentiation; GO:0030178|negative regulation of Wnt signaling pathway; GO:0030510|regulation of BMP signaling pathway; GO:0036342|post-anal tail morphogenesis; GO:0043433|negative regulation of DNA-binding transcription factor activity; GO:0043508|negative regulation of JUN kinase activity; GO:0048546|digestive tract morphogenesis; GO:0051898|negative regulation of protein kinase B signaling; GO:0060028|convergent extension involved in axis elongation; GO:0060070|canonical Wnt signaling pathway; GO:0090090|negative regulation of canonical Wnt signaling pathway; GO:0090175|regulation of establishment of planar polarity; GO:0090179|planar cell polarity pathway involved in neural tube closure; GO:2000041|negative regulation of planar cell polarity pathway involved in axis elongation; GO:2000057|negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis	GO:0005576|extracellular region; GO:0016021|integral component of membrane	GO:0004930|G protein-coupled receptor activity; GO:0017147|Wnt-protein binding; GO:0042813|Wnt-activated receptor activity	ko:K02222|SFRP5	ko04310|Wnt signaling pathway	1369	NP_001305376.1	NP_001305376.1 secreted frizzled-related protein 5 precursor [Gallus gallus]	sp|Q9WU66|SFRP5_MOUSE	sp|Q9WU66|SFRP5_MOUSE Secreted frizzled-related protein 5 OS=Mus musculus GN=Sfrp5 PE=2 SV=1	9031.ENSGALP00000012135	secreted frizzled-related protein 5	_	KOG3577	_	PF01392.19|Fz|Fz domain|ENSGALT00000012149|m.5031:50-156;PF01759.18|NTR|UNC-6/NTR/C345C module|ENSGALT00000012149|m.5031:193-268
ENSGALG00000007570	1.080274079	0.212005975	2.296020443	4.56E-09	1.86E-08	up	yes	1.034198528	0.913818902	1.292804808	0.179543955	0.209754737	0.246719233	4	11440335	11449639	-	ENSGALG00000007570	protein_coding	GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0001525|angiogenesis; GO:0006366|transcription by RNA polymerase II; GO:0008284|positive regulation of cell population proliferation; GO:0030033|microvillus assembly; GO:0032534|regulation of microvillus assembly; GO:0035914|skeletal muscle cell differentiation; GO:0045600|positive regulation of fat cell differentiation; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0060576|intestinal epithelial cell development; GO:0071407|cellular response to organic cyclic compound; GO:1901653|cellular response to peptide; GO:1990830|cellular response to leukemia inhibitory factor	GO:0005654|nucleoplasm; GO:0005794|Golgi apparatus; GO:0043231|intracellular membrane-bounded organelle	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0008134|transcription factor binding; GO:0046872|metal ion binding"	ko:K09206|KLF5	--	1987	XP_004940833.2	XP_004940833.2 Krueppel-like factor 5 isoform X4 [Gallus gallus]	sp|Q13887|KLF5_HUMAN	sp|Q13887|KLF5_HUMAN Krueppel-like factor 5 OS=Homo sapiens GN=KLF5 PE=1 SV=2	9031.ENSGALP00000012227	similar to Zinc finger protein 534	COG5048	KOG1721	_	_
ENSGALG00000007596	3.535892352	7.48466724	-1.079715686	5.83E-23	6.49E-22	down	yes	3.155951936	3.331525672	4.120199447	7.036818755	7.793527517	7.623655448	12	15030285	15057873	+	ENSGALG00000007596	protein_coding	GO:0035873|lactate transmembrane transport; GO:1901475|pyruvate transmembrane transport	GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane	GO:0005477|pyruvate secondary active transmembrane transporter activity; GO:0008028|monocarboxylic acid transmembrane transporter activity; GO:0015129|lactate transmembrane transporter activity; GO:0015293|symporter activity; GO:0050833|pyruvate transmembrane transporter activity	ko:K08184|SLC16A7	--	5472	XP_025010337.1	XP_025010337.1 monocarboxylate transporter 2-like isoform X3 [Gallus gallus]	sp|O60669|MOT2_HUMAN	sp|O60669|MOT2_HUMAN Monocarboxylate transporter 2 OS=Homo sapiens GN=SLC16A7 PE=1 SV=2	9031.ENSGALP00000012273	hypothetical LOC416086	COG0477	KOG2504	_	PF07690.13|MFS_1|Major Facilitator Superfamily|ENSGALT00000099766|m.8002:33-409
ENSGALG00000007599	7.954490337	2.792348893	1.506945461	1.41E-42	3.98E-41	up	yes	8.301054261	7.467637259	8.09477949	2.812398356	2.869746549	2.694901774	4	11668128	11671967	+	AMER1	protein_coding	GO:0016055|Wnt signaling pathway; GO:0031398|positive regulation of protein ubiquitination; GO:0043161|proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0048856|anatomical structure development; GO:0060348|bone development; GO:0060612|adipose tissue development; GO:0060828|regulation of canonical Wnt signaling pathway; GO:0072161|mesenchymal cell differentiation involved in kidney development; GO:0090090|negative regulation of canonical Wnt signaling pathway; GO:0090263|positive regulation of canonical Wnt signaling pathway; GO:1903364|positive regulation of cellular protein catabolic process; GO:1904885|beta-catenin destruction complex assembly; GO:1904886|beta-catenin destruction complex disassembly	GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0016604|nuclear body; GO:0043231|intracellular membrane-bounded organelle	"GO:0005546|phosphatidylinositol-4,5-bisphosphate binding; GO:0008013|beta-catenin binding; GO:1904713|beta-catenin destruction complex binding"	ko:K19407|AMER1	--	3580	XP_004940836.1	XP_004940836.1 APC membrane recruitment protein 1 [Gallus gallus]	sp|Q5JTC6|AMER1_HUMAN	sp|Q5JTC6|AMER1_HUMAN APC membrane recruitment protein 1 OS=Homo sapiens GN=AMER1 PE=1 SV=2	_	_	_	_	_	PF09422.7|WTX|WTX protein|ENSGALT00000012291|m.16472:95-534
ENSGALG00000007636	0.139343419	1.702282296	-3.519214997	1.15E-20	1.11E-19	down	yes	0.248002954	0.111899065	0.058128239	1.679145511	1.659887507	1.76781387	20	11554555	11562277	-	PCK1	protein_coding	GO:0006089|lactate metabolic process; GO:0006090|pyruvate metabolic process; GO:0006094|gluconeogenesis; GO:0006111|regulation of gluconeogenesis; GO:0006522|alanine metabolic process; GO:0006531|aspartate metabolic process; GO:0006536|glutamate metabolic process; GO:0006541|glutamine metabolic process; GO:0006544|glycine metabolic process; GO:0006560|proline metabolic process; GO:0006735|NADH regeneration; GO:0007296|vitellogenesis; GO:0007568|aging; GO:0007586|digestion; GO:0008343|adult feeding behavior; GO:0009069|serine family amino acid metabolic process; GO:0009792|embryo development ending in birth or egg hatching; GO:0015743|malate transport; GO:0016042|lipid catabolic process; GO:0018991|oviposition; GO:0019543|propionate catabolic process; GO:0019563|glycerol catabolic process; GO:0019953|sexual reproduction; GO:0030703|eggshell formation; GO:0032496|response to lipopolysaccharide; GO:0032869|cellular response to insulin stimulus; GO:0033993|response to lipid; GO:0042149|cellular response to glucose starvation; GO:0042594|response to starvation; GO:0043950|positive regulation of cAMP-mediated signaling; GO:0045722|positive regulation of gluconeogenesis; GO:0045912|negative regulation of carbohydrate metabolic process; GO:0045913|positive regulation of carbohydrate metabolic process; GO:0046015|regulation of transcription by glucose; GO:0046898|response to cycloheximide; GO:0048562|embryonic organ morphogenesis; GO:0048589|developmental growth; GO:0050892|intestinal absorption; GO:0051384|response to glucocorticoid; GO:0051591|response to cAMP; GO:0060259|regulation of feeding behavior; GO:0070365|hepatocyte differentiation; GO:0070741|response to interleukin-6; GO:0071300|cellular response to retinoic acid; GO:0071320|cellular response to cAMP; GO:0071332|cellular response to fructose stimulus; GO:0071333|cellular response to glucose stimulus; GO:0071347|cellular response to interleukin-1; GO:0071356|cellular response to tumor necrosis factor; GO:0071361|cellular response to ethanol; GO:0071374|cellular response to parathyroid hormone stimulus; GO:0071377|cellular response to glucagon stimulus; GO:0071456|cellular response to hypoxia; GO:0071549|cellular response to dexamethasone stimulus; GO:0072071|kidney interstitial fibroblast differentiation; GO:1904640|response to methionine	GO:0005829|cytosol	GO:0003729|mRNA binding; GO:0004550|nucleoside diphosphate kinase activity; GO:0004613|phosphoenolpyruvate carboxykinase (GTP) activity; GO:0005525|GTP binding; GO:0008906|inosine kinase activity; GO:0019157|malate oxidase activity; GO:0030145|manganese ion binding; GO:0043565|sequence-specific DNA binding; GO:0047134|protein-disulfide reductase activity; GO:0050692|DBD domain binding; GO:0051379|epinephrine binding	"ko:K01596|E4.1.1.32,pckA,PCK"	ko00010|Glycolysis / Gluconeogenesis; ko00020|Citrate cycle (TCA cycle); ko00620|Pyruvate metabolism; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko01120|Microbial metabolism in diverse environments; ko01130|Biosynthesis of antibiotics; ko03320|PPAR signaling pathway; ko04068|FoxO signaling pathway; ko04151|PI3K-Akt signaling pathway; ko04152|AMPK signaling pathway; ko04910|Insulin signaling pathway; ko04920|Adipocytokine signaling pathway; ko04922|Glucagon signaling pathway; ko04931|Insulin resistance; ko04964|Proximal tubule bicarbonate reclamation	2762	POI33385.1	POI33385.1 hypothetical protein CIB84_002863 [Bambusicola thoracicus]	sp|P05153|PCKGC_CHICK	"sp|P05153|PCKGC_CHICK Phosphoenolpyruvate carboxykinase, cytosolic [GTP] OS=Gallus gallus GN=PCK1 PE=2 SV=1"	9031.ENSGALP00000012342	"Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (PEPCK-C)(EC 4.1.1.32)(Phosphoenolpyruvat [...] "	COG1274	KOG3749	_	PF00821.15|PEPCK|Phosphoenolpyruvate carboxykinase|ENSGALT00000012356|m.3597:29-619
ENSGALG00000007645	2.711241092	0.912716869	1.560304842	3.03E-10	1.38E-09	up	yes	3.432712839	2.455104402	2.245906034	0.665408172	1.124413659	0.948328776	6	23492176	23498630	+	ENSGALG00000007645	protein_coding	--	GO:0005783|endoplasmic reticulum; GO:0005793|endoplasmic reticulum-Golgi intermediate compartment; GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0016324|apical plasma membrane; GO:0031528|microvillus membrane	--	--	--	2502	XP_004942263.1	XP_004942263.1 prominin-1-A [Gallus gallus]	sp|Q9W735|PRM1A_DANRE	sp|Q9W735|PRM1A_DANRE Prominin-1-A OS=Danio rerio GN=prom1a PE=2 SV=2	9031.ENSGALP00000038609	Prominin-like protein Fragment 	_	KOG4331	_	PF05478.8|Prominin|Prominin|ENSGALT00000096552|m.5104:19-759
ENSGALG00000007646	0.115894818	0.270058962	-1.153511693	0.010592879	0.018644393	down	yes	0.099940949	0.154695446	0.093048059	0.304917811	0.228374062	0.276885014	4	11924118	12042777	+	ENSGALG00000007646	protein_coding	GO:0001525|angiogenesis; GO:0001568|blood vessel development; GO:0002040|sprouting angiogenesis; GO:0007169|transmembrane receptor protein tyrosine kinase signaling pathway; GO:0018108|peptidyl-tyrosine phosphorylation; GO:0030154|cell differentiation; GO:0030878|thyroid gland development; GO:0035050|embryonic heart tube development; GO:0048844|artery morphogenesis	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0004713|protein tyrosine kinase activity; GO:0004714|transmembrane receptor protein tyrosine kinase activity; GO:0005524|ATP binding	"ko:K05096|FLT1,VEGFR1"	ko04014|Ras signaling pathway; ko04015|Rap1 signaling pathway; ko04060|Cytokine-cytokine receptor interaction; ko04066|HIF-1 signaling pathway; ko04144|Endocytosis; ko04151|PI3K-Akt signaling pathway; ko04510|Focal adhesion; ko05202|Transcriptional misregulation in cancer; ko05323|Rheumatoid arthritis	4745	XP_420292.4	XP_420292.4 vascular endothelial growth factor receptor kdr-like isoform X2 [Gallus gallus]	sp|Q8AXB3|VGFR4_DANRE	sp|Q8AXB3|VGFR4_DANRE Vascular endothelial growth factor receptor kdr-like OS=Danio rerio GN=kdrl PE=1 SV=1	9031.ENSGALP00000012356	similar to receptor tyrosine kinase flk-1/VEGFR-2	COG0515	KOG0200	_	PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000012370|m.16487:807-1137;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000012370|m.16487:232-306;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000012370|m.16487:341-401;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000012370|m.16487:549-619;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000012370|m.16487:647-714;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000012370|m.16487:341-403;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000012370|m.16487:439-537;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000012370|m.16487:642-727;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000012370|m.16487:38-117;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000012370|m.16487:235-309;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000012370|m.16487:547-626;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000012370|m.16487:649-723;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000012370|m.16487:810-904;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000012370|m.16487:975-1135;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000012370|m.16487:651-721
ENSGALG00000007661	2.121391367	0.870223835	1.275853183	1.98E-10	9.16E-10	up	yes	1.633165894	2.214811341	2.516196866	1.020774727	0.767323011	0.822573766	18	10324832	10337709	-	MYCBPAP	protein_coding	GO:0007268|chemical synaptic transmission; GO:0007275|multicellular organism development; GO:0007283|spermatogenesis; GO:0030154|cell differentiation	GO:0005737|cytoplasm; GO:0016020|membrane	--	--	--	3435	XP_015150978.1	"XP_015150978.1 radical S-adenosyl methionine domain-containing protein 1, mitochondrial isoform X5 [Gallus gallus]"	sp|Q8TBZ2|MYBPP_HUMAN	sp|Q8TBZ2|MYBPP_HUMAN MYCBP-associated protein OS=Homo sapiens GN=MYCBPAP PE=1 SV=2	9031.ENSGALP00000012396	MYCBP associated protein	_	_	NOG84836	PF14646.3|MYCBPAP|MYCBP-associated protein family|ENSGALT00000100535|m.13247:249-665
ENSGALG00000007690	3.447357731	11.16512364	-1.692549002	6.85E-27	9.39E-26	down	yes	3.481445382	3.642472414	3.218155398	11.35915052	10.25712345	11.87909696	20	11939844	11947261	-	TFAP2C	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006357|regulation of transcription by RNA polymerase II; GO:0007267|cell-cell signaling; GO:0008584|male gonad development; GO:0040029|regulation of gene expression, epigenetic; GO:0042127|regulation of cell population proliferation; GO:0045944|positive regulation of transcription by RNA polymerase II"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005739|mitochondrion; GO:0005829|cytosol	"GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding; GO:0001047|core promoter binding; GO:0001227|DNA-binding transcription repressor activity, RNA polymerase II-specific; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity; GO:0046983|protein dimerization activity"	ko:K09177|TFAP2C	--	1347	XP_417497.2	XP_417497.2 transcription factor AP-2 gamma [Gallus gallus]	sp|Q92754|AP2C_HUMAN	sp|Q92754|AP2C_HUMAN Transcription factor AP-2 gamma OS=Homo sapiens GN=TFAP2C PE=1 SV=1	9031.ENSGALP00000012451	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	_	KOG3811	_	PF03299.11|TF_AP-2|Transcription factor AP-2|ENSGALT00000012465|m.3609:223-417
ENSGALG00000007717	0.870818608	3.722058921	-2.08305491	4.53E-33	8.38E-32	down	yes	0.764365383	1.074929564	0.773160878	3.836670956	3.929948298	3.399557509	20	11976791	11984112	+	GCNT7	protein_coding	GO:0006486|protein glycosylation	GO:0000139|Golgi membrane; GO:0016021|integral component of membrane	GO:0008375|acetylglucosaminyltransferase activity	--	--	4138	XP_001231953.2	"XP_001231953.2 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7 [Gallus gallus]"	sp|Q6ZNI0|GCNT7_HUMAN	"sp|Q6ZNI0|GCNT7_HUMAN Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7 OS=Homo sapiens GN=GCNT7 PE=2 SV=2"	9031.ENSGALP00000012494	annotation not avaliable	_	KOG0799	_	PF02485.18|Branch|Core-2/I-Branching enzyme|ENSGALT00000012508|m.3612:113-375
ENSGALG00000007720	2.130656331	4.349884322	-1.026236659	5.43E-12	2.85E-11	down	yes	2.253851994	2.243325776	1.894791222	4.682569839	4.803346294	3.563736832	15	10329429	10349666	+	AIFM3	protein_coding	GO:0097194|execution phase of apoptosis	GO:0005739|mitochondrion; GO:0005743|mitochondrial inner membrane; GO:0005783|endoplasmic reticulum; GO:0005829|cytosol	"GO:0016491|oxidoreductase activity; GO:0046872|metal ion binding; GO:0050660|flavin adenine dinucleotide binding; GO:0051537|2 iron, 2 sulfur cluster binding"	--	--	4297	XP_003642264.1	XP_003642264.1 apoptosis-inducing factor 3 isoform X5 [Gallus gallus]	sp|Q96NN9|AIFM3_HUMAN	sp|Q96NN9|AIFM3_HUMAN Apoptosis-inducing factor 3 OS=Homo sapiens GN=AIFM3 PE=1 SV=1	_	_	_	_	_	PF07992.11|Pyr_redox_2|Pyridine nucleotide-disulphide oxidoreductase|ENSGALT00000104108|m.11014:236-533;PF00070.24|Pyr_redox|Pyridine nucleotide-disulphide oxidoreductase|ENSGALT00000104108|m.11014:374-454;PF00355.23|Rieske|Rieske [2Fe-2S] domain|ENSGALT00000104108|m.11014:111-194;PF13738.3|Pyr_redox_3|Pyridine nucleotide-disulphide oxidoreductase|ENSGALT00000104108|m.11014:295-506;PF14759.3|Reductase_C|Reductase C-terminal|ENSGALT00000104108|m.11014:552-623;PF13806.3|Rieske_2|Rieske-like [2Fe-2S] domain|ENSGALT00000104108|m.11014:111-206
ENSGALG00000007744	0.933297392	4.174525084	-2.149279312	2.12E-25	2.71E-24	down	yes	1.194409675	0.90445507	0.701027431	3.984554001	4.669638533	3.869382717	20	11992062	12008045	-	CASS4	protein_coding	GO:0007155|cell adhesion	GO:0005737|cytoplasm; GO:0005856|cytoskeleton; GO:0005925|focal adhesion	--	--	--	2613	XP_015737319.1	XP_015737319.1 PREDICTED: cas scaffolding protein family member 4 isoform X1 [Coturnix japonica]	sp|Q9NQ75|CASS4_HUMAN	sp|Q9NQ75|CASS4_HUMAN Cas scaffolding protein family member 4 OS=Homo sapiens GN=CASS4 PE=1 SV=2	9031.ENSGALP00000012540	chromosome 20 open reading frame 32	_	_	NOG72030	PF08824.7|Serine_rich|Serine rich protein interaction domain|ENSGALT00000071291|m.3617:461-617;PF12026.5|DUF3513|Domain of unknown function (DUF3513)|ENSGALT00000071291|m.3617:684-817;PF14604.3|SH3_9|Variant SH3 domain|ENSGALT00000071291|m.3617:14-62;PF00018.25|SH3_1|SH3 domain|ENSGALT00000071291|m.3617:13-61;PF07653.14|SH3_2|Variant SH3 domain|ENSGALT00000071291|m.3617:12-64
ENSGALG00000007748	2.147610911	0.920450455	1.213433486	3.08E-07	1.04E-06	up	yes	2.157925319	2.25808087	2.026826544	1.158445202	0.73744845	0.865457715	4	12310289	12331702	+	SLC16A2	protein_coding	GO:0006810|transport; GO:0015718|monocarboxylic acid transport; GO:0043252|sodium-independent organic anion transport; GO:0070327|thyroid hormone transport	GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane	GO:0005215|transporter activity; GO:0008028|monocarboxylic acid transmembrane transporter activity; GO:0015293|symporter activity; GO:0015349|thyroid hormone transmembrane transporter activity	ko:K08231|SLC16A2	ko04919|Thyroid hormone signaling pathway	2515	NP_001308666.1	NP_001308666.1 monocarboxylate transporter 8 [Gallus gallus]	sp|P36021|MOT8_HUMAN	sp|P36021|MOT8_HUMAN Monocarboxylate transporter 8 OS=Homo sapiens GN=SLC16A2 PE=1 SV=2	9031.ENSGALP00000012547	"solute carrier family 16, member 2 (monocarboxylic acid transporter 8)"	_	KOG2504	_	PF07690.13|MFS_1|Major Facilitator Superfamily|ENSGALT00000012561|m.16505:105-439
ENSGALG00000007781	1.548950719	0.50223079	1.605709441	1.20E-05	3.34E-05	up	yes	1.480311539	1.642715663	1.523824953	0.436423746	0.474695516	0.595573109	15	11080655	11083506	+	GAL3ST1	protein_coding	GO:0006487|protein N-linked glycosylation; GO:0006682|galactosylceramide biosynthetic process; GO:0007283|spermatogenesis; GO:0042552|myelination	GO:0000139|Golgi membrane; GO:0005887|integral component of plasma membrane; GO:0016020|membrane	GO:0001733|galactosylceramide sulfotransferase activity; GO:0008146|sulfotransferase activity	ko:K01019|GAL3ST1	ko00565|Ether lipid metabolism; ko00600|Sphingolipid metabolism; ko01100|Metabolic pathways	1317	XP_004934501.1	XP_004934501.1 galactosylceramide sulfotransferase isoform X1 [Gallus gallus]	sp|Q99999|G3ST1_HUMAN	sp|Q99999|G3ST1_HUMAN Galactosylceramide sulfotransferase OS=Homo sapiens GN=GAL3ST1 PE=1 SV=1	9031.ENSGALP00000012608	galactose-3-O-sulfotransferase 1	_	_	NOG45565	PF06990.8|Gal-3-0_sulfotr|Galactose-3-O-sulfotransferase|ENSGALT00000012622|m.11057:20-422
ENSGALG00000007785	68.92452097	16.39678247	2.070934295	1.04E-76	7.78E-75	up	yes	68.69078758	70.31715342	67.76562192	19.90790195	13.60203437	15.6804111	12	16703105	16707773	-	PROK2	protein_coding	--	GO:0005576|extracellular region	GO:0090729|toxin activity	--	--	1123	XP_015148719.1	XP_015148719.1 prokineticin-2 [Gallus gallus]	sp|Q2XXR8|VAR1_VARVA	sp|Q2XXR8|VAR1_VARVA AVIToxin-VAR1 OS=Varanus varius PE=2 SV=1	9031.ENSGALP00000012612	prokineticin 2	_	_	NOG39081	PF06607.8|Prokineticin|Prokineticin|ENSGALT00000012626|m.8039:8-99
ENSGALG00000007803	0.605801911	0.27753367	1.09873544	0.01642688	0.027768046	up	yes	0.342320919	0.752969985	0.722114829	0.24762191	0.281187704	0.303791396	6	23783093	23787154	-	ENSGALG00000007803	protein_coding	GO:0008645|hexose transmembrane transport; GO:0046415|urate metabolic process; GO:1904659|glucose transmembrane transport	GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0016323|basolateral plasma membrane; GO:0016324|apical plasma membrane	GO:0005351|carbohydrate:proton symporter activity; GO:0005355|glucose transmembrane transporter activity; GO:0015143|urate transmembrane transporter activity; GO:0022857|transmembrane transporter activity	"ko:K08146|SLC2A9,GLUT9"	--	2001	XP_019473292.1	"XP_019473292.1 PREDICTED: solute carrier family 2, facilitated glucose transporter member 5-like isoform X1 [Meleagris gallopavo]"	sp|Q9NRM0|GTR9_HUMAN	"sp|Q9NRM0|GTR9_HUMAN Solute carrier family 2, facilitated glucose transporter member 9 OS=Homo sapiens GN=SLC2A9 PE=1 SV=2"	_	_	_	_	_	PF00083.21|Sugar_tr|Sugar (and other) transporter|ENSGALT00000012658|m.5128:168-291;PF00083.21|Sugar_tr|Sugar (and other) transporter|ENSGALT00000012658|m.5128:373-618;PF00083.21|Sugar_tr|Sugar (and other) transporter|ENSGALT00000012658|m.5129:41-119
ENSGALG00000007819	0.36878888	1.275651772	-1.763034046	1.40E-08	5.42E-08	down	yes	0.332817674	0.554595927	0.218953039	1.26326845	1.370129627	1.193557238	12	17007247	17127236	-	PDZRN3	protein_coding	GO:0007528|neuromuscular junction development; GO:0016567|protein ubiquitination	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005829|cytosol; GO:0031594|neuromuscular junction	GO:0004842|ubiquitin-protein transferase activity; GO:0008270|zinc ion binding; GO:0061630|ubiquitin protein ligase activity	"ko:K15682|PDZRN3_4,LNX3_4"	--	3483	XP_414432.2	XP_414432.2 E3 ubiquitin-protein ligase PDZRN3 isoform X1 [Gallus gallus]	sp|Q9UPQ7|PZRN3_HUMAN	sp|Q9UPQ7|PZRN3_HUMAN E3 ubiquitin-protein ligase PDZRN3 OS=Homo sapiens GN=PDZRN3 PE=1 SV=2	9031.ENSGALP00000012678	PDZ domain containing RING finger 3	_	KOG0297;KOG0312	_	"PF00595.21|PDZ|PDZ domain (Also known as DHR or GLGF)|ENSGALT00000065944|m.8050:250-333;PF00595.21|PDZ|PDZ domain (Also known as DHR or GLGF)|ENSGALT00000065944|m.8050:433-513;PF13180.3|PDZ_2|PDZ domain|ENSGALT00000065944|m.8050:272-337;PF13180.3|PDZ_2|PDZ domain|ENSGALT00000065944|m.8050:453-515;PF13923.3|zf-C3HC4_2|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000065944|m.8050:17-53;PF00097.22|zf-C3HC4|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000065944|m.8050:18-53;PF13445.3|zf-RING_UBOX|RING-type zinc-finger|ENSGALT00000065944|m.8050:18-53"
ENSGALG00000007845	7.900728806	23.13975867	-1.549114634	1.12E-89	1.10E-87	down	yes	7.947036275	7.591219516	8.163930627	22.59314671	23.6501474	23.17598189	3	2054433	2088375	+	REL	protein_coding	GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006309|apoptotic DNA fragmentation; GO:0006954|inflammatory response; GO:0007249|I-kappaB kinase/NF-kappaB signaling; GO:0034097|response to cytokine; GO:0038061|NIK/NF-kappaB signaling; GO:0045087|innate immune response; GO:0045944|positive regulation of transcription by RNA polymerase II	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0033256|I-kappaB/NF-kappaB complex	"GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding; GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0003677|DNA binding; GO:0003682|chromatin binding; GO:0003700|DNA-binding transcription factor activity; GO:0042803|protein homodimerization activity; GO:0046982|protein heterodimerization activity"	ko:K09254|REL	ko04014|Ras signaling pathway; ko04624|Toll and Imd signaling pathway; ko05202|Transcriptional misregulation in cancer; ko05203|Viral carcinogenesis	3766	NP_001161198.1	NP_001161198.1 proto-oncogene c-Rel [Gallus gallus]	sp|P16236|REL_CHICK	sp|P16236|REL_CHICK Proto-oncogene c-Rel OS=Gallus gallus GN=REL PE=1 SV=2	9031.ENSGALP00000012728	C-Rel proto-oncogene protein (C-Rel protein)(p68); Proto-oncogene that may play a role in di [...] 	_	_	NOG119056	PF00554.19|RHD_DNA_bind|Rel homology DNA-binding domain|ENSGALT00000040305|m.10554:46-214;PF16179.2|RHD_dimer|Rel homology dimerisation domain|ENSGALT00000040305|m.10554:223-318
ENSGALG00000007912	19.57030814	53.66037583	-1.454722522	8.56E-110	1.34E-107	down	yes	20.56594499	19.04837315	19.09660629	53.1051859	53.6827901	54.19315151	20	13107712	13155856	+	ATP9A	protein_coding	"GO:0006890|retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; GO:0006897|endocytosis; GO:0045332|phospholipid translocation"	GO:0005769|early endosome; GO:0005802|trans-Golgi network; GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0031901|early endosome membrane; GO:0048471|perinuclear region of cytoplasm; GO:0055037|recycling endosome	GO:0000287|magnesium ion binding; GO:0005524|ATP binding; GO:0140326|ATPase-coupled intramembrane lipid transporter activity	ko:K01530|E3.6.3.1	--	3241	XP_015152004.1	XP_015152004.1 probable phospholipid-transporting ATPase IIA isoform X1 [Gallus gallus]	sp|O75110|ATP9A_HUMAN	sp|O75110|ATP9A_HUMAN Probable phospholipid-transporting ATPase IIA OS=Homo sapiens GN=ATP9A PE=1 SV=3	9031.ENSGALP00000012834	"ATPase, class II, type 9A"	COG0474	KOG0210	_	PF16212.2|PhoLip_ATPase_C|Phospholipid-translocating P-type ATPase C-terminal|ENSGALT00000012849|m.3648:844-1071;PF16209.2|PhoLip_ATPase_N|Phospholipid-translocating ATPase N-terminal|ENSGALT00000012849|m.3648:79-137;PF00702.23|Hydrolase|haloacid dehalogenase-like hydrolase|ENSGALT00000012849|m.3648:420-724;PF00122.17|E1-E2_ATPase|E1-E2 ATPase|ENSGALT00000012849|m.3648:171-381;PF13246.3|Cation_ATPase|Cation transport ATPase (P-type)|ENSGALT00000012849|m.3648:522-603
ENSGALG00000007919	23.70375098	11.42793903	1.051896762	1.47E-25	1.89E-24	up	yes	23.33773135	22.95670123	24.81682035	12.22712033	10.62021848	11.43647829	9	15767947	15786451	-	EIF4E2	protein_coding	GO:0001701|in utero embryonic development; GO:0017148|negative regulation of translation	GO:0005737|cytoplasm; GO:0005845|mRNA cap binding complex	GO:0003723|RNA binding; GO:0003743|translation initiation factor activity; GO:0031625|ubiquitin protein ligase binding	ko:K03259|EIF4E	ko01521|EGFR tyrosine kinase inhibitor resistance; ko03013|RNA transport; ko04066|HIF-1 signaling pathway; ko04150|mTOR signaling pathway; ko04151|PI3K-Akt signaling pathway; ko04211|Longevity regulating pathway; ko04910|Insulin signaling pathway	1295	XP_003641810.1	XP_003641810.1 eukaryotic translation initiation factor 4E type 2 isoform X3 [Gallus gallus]	sp|Q8BMB3|IF4E2_MOUSE	sp|Q8BMB3|IF4E2_MOUSE Eukaryotic translation initiation factor 4E type 2 OS=Mus musculus GN=Eif4e2 PE=1 SV=1	_	_	_	_	_	PF01652.15|IF4E|Eukaryotic initiation factor 4E|ENSGALT00000050326|m.9054:55-215
ENSGALG00000007920	0.555389234	1.96120357	-1.801760457	4.87E-14	3.03E-13	down	yes	0.419491184	0.516280397	0.73039612	2.096364136	1.913858405	1.873388169	5	19671101	19710796	+	PRR5L	protein_coding	GO:0001933|negative regulation of protein phosphorylation; GO:0009968|negative regulation of signal transduction; GO:0010762|regulation of fibroblast migration; GO:0034599|cellular response to oxidative stress; GO:0038203|TORC2 signaling; GO:0061014|positive regulation of mRNA catabolic process; GO:0090316|positive regulation of intracellular protein transport	GO:0031932|TORC2 complex	--	--	--	3517	XP_004941606.2	XP_004941606.2 proline-rich protein 5-like [Gallus gallus]	sp|Q5E9R0|PRR5L_BOVIN	sp|Q5E9R0|PRR5L_BOVIN Proline-rich protein 5-like OS=Bos taurus GN=PRR5L PE=2 SV=1	9031.ENSGALP00000012846	proline rich 5 like	_	_	NOG84751	PF08539.8|HbrB|HbrB-like|ENSGALT00000012861|m.2890:51-150
ENSGALG00000007929	0.363821709	1.498983822	-2.013155081	1.19E-14	7.73E-14	down	yes	0.241536049	0.380753048	0.469176029	1.262861527	1.643057943	1.591031995	24	6196567	6228780	-	DIXDC1	protein_coding	GO:0007049|cell cycle; GO:0021799|cerebral cortex radially oriented cell migration; GO:0021869|forebrain ventricular zone progenitor cell division; GO:0032956|regulation of actin cytoskeleton organization; GO:0045665|negative regulation of neuron differentiation; GO:0060070|canonical Wnt signaling pathway; GO:0070507|regulation of microtubule cytoskeleton organization; GO:0090263|positive regulation of canonical Wnt signaling pathway	GO:0005829|cytosol; GO:0005925|focal adhesion	GO:0003779|actin binding; GO:0019904|protein domain specific binding; GO:0043015|gamma-tubulin binding	--	--	3490	XP_004948207.1	XP_004948207.1 dixin isoform X5 [Gallus gallus]	sp|Q155Q3|DIXC1_HUMAN	sp|Q155Q3|DIXC1_HUMAN Dixin OS=Homo sapiens GN=DIXDC1 PE=1 SV=2	9031.ENSGALP00000012864	DIX domain containing 1	_	KOG3571	_	PF00778.14|DIX|DIX domain|ENSGALT00000096549|m.6469:389-467
ENSGALG00000007955	7.867423905	70.06661784	-3.153137329	1.09E-272	2.20E-269	down	yes	8.47123619	6.935748134	8.195287391	70.79207856	66.40379729	73.00397768	18	10639258	10647713	+	SLC16A5	protein_coding	GO:0015718|monocarboxylic acid transport	GO:0005887|integral component of plasma membrane; GO:0016020|membrane	GO:0008028|monocarboxylic acid transmembrane transporter activity; GO:0015293|symporter activity	ko:K08182|SLC16A5	--	1866	XP_420120.4	XP_420120.4 monocarboxylate transporter 6 [Gallus gallus]	sp|O15375|MOT6_HUMAN	sp|O15375|MOT6_HUMAN Monocarboxylate transporter 6 OS=Homo sapiens GN=SLC16A5 PE=2 SV=1	9031.ENSGALP00000012905	"solute carrier family 16, member 5 (monocarboxylic acid transporter 6)"	_	KOG2504	_	PF07690.13|MFS_1|Major Facilitator Superfamily|ENSGALT00000012920|m.13317:39-400;PF07690.13|MFS_1|Major Facilitator Superfamily|ENSGALT00000012920|m.13317:328-454
ENSGALG00000007965	86.87525363	32.008495	1.440205844	4.20E-114	7.47E-112	up	yes	88.14082363	87.53850354	84.94643373	32.14262303	33.3015691	30.58129286	18	10646850	10667777	-	JPT1	protein_coding	--	GO:0005730|nucleolus; GO:0005737|cytoplasm; GO:0031965|nuclear membrane	--	--	--	1421	DAA05619.1	DAA05619.1 TPA_inf: HN1 [Gallus gallus]	sp|Q3T0T5|JUPI1_BOVIN	sp|Q3T0T5|JUPI1_BOVIN Jupiter microtubule associated homolog 1 OS=Bos taurus GN=JPT1 PE=2 SV=3	9031.ENSGALP00000012919	hematological and neurological expressed 1 	_	_	NOG85721	_
ENSGALG00000007972	0.935680171	1.895960882	-1.011094258	1.07E-05	3.00E-05	down	yes	0.760489946	0.929319815	1.117230753	1.995587528	1.933527818	1.758767301	4	13079135	13140422	+	TRPC5	protein_coding	--	GO:0005886|plasma membrane; GO:0034704|calcium channel complex	"GO:0005262|calcium channel activity; GO:0070679|inositol 1,4,5 trisphosphate binding"	ko:K04968|TRPC5	ko04360|Axon guidance	2910	XP_420310.2	XP_420310.2 short transient receptor potential channel 5 [Gallus gallus]	sp|O62852|TRPC5_RABIT	sp|O62852|TRPC5_RABIT Short transient receptor potential channel 5 OS=Oryctolagus cuniculus GN=TRPC5 PE=2 SV=1	_	_	_	_	_	PF00520.28|Ion_trans|Ion transport protein|ENSGALT00000012944|m.16525:379-635;PF08344.8|TRP_2|Transient receptor ion channel II|ENSGALT00000012944|m.16525:176-238
ENSGALG00000007986	16.56873224	5.41046499	1.612845167	9.42E-39	2.22E-37	up	yes	16.10317577	15.43129466	18.17172629	5.564154082	5.524517887	5.142723002	20	13383258	13384664	-	MOCS3	protein_coding	GO:0002098|tRNA wobble uridine modification; GO:0002143|tRNA wobble position uridine thiolation; GO:0006777|Mo-molybdopterin cofactor biosynthetic process; GO:0018192|enzyme active site formation via cysteine modification to L-cysteine persulfide; GO:0032324|molybdopterin cofactor biosynthetic process; GO:0032447|protein urmylation; GO:0034227|tRNA thio-modification	GO:0005829|cytosol	GO:0004792|thiosulfate sulfurtransferase activity; GO:0005524|ATP binding; GO:0016779|nucleotidyltransferase activity; GO:0016783|sulfurtransferase activity; GO:0042292|URM1 activating enzyme activity; GO:0046872|metal ion binding; GO:0061604|molybdopterin-synthase sulfurtransferase activity; GO:0061605|molybdopterin-synthase adenylyltransferase activity	"ko:K11996|MOCS3,UBA4"	ko04122|Sulfur relay system	1407	XP_001232656.1	XP_001232656.1 adenylyltransferase and sulfurtransferase MOCS3 [Gallus gallus]	sp|O95396|MOCS3_HUMAN	sp|O95396|MOCS3_HUMAN Adenylyltransferase and sulfurtransferase MOCS3 OS=Homo sapiens GN=MOCS3 PE=1 SV=1	9031.ENSGALP00000012949	molybdenum cofactor synthesis 3	COG0476;COG0607	KOG2017	_	PF00899.18|ThiF|ThiF family|ENSGALT00000012964|m.3653:72-307;PF00581.17|Rhodanese|Rhodanese-like domain|ENSGALT00000012964|m.3653:346-459
ENSGALG00000008006	1.588185589	3.465407457	-1.120747179	1.08E-06	3.43E-06	down	yes	1.50620166	1.161469832	2.096885275	3.887739658	3.183899102	3.324583612	4	13332487	13379286	+	CAPN6	protein_coding	GO:0006508|proteolysis	GO:0005737|cytoplasm; GO:0005925|focal adhesion; GO:0009986|cell surface; GO:0070062|extracellular exosome	GO:0004198|calcium-dependent cysteine-type endopeptidase activity	ko:K08575|CAPN6	--	2029	XP_420313.2	XP_420313.2 calpain-6 [Gallus gallus]	sp|O08688|CAN5_MOUSE	sp|O08688|CAN5_MOUSE Calpain-5 OS=Mus musculus GN=Capn5 PE=1 SV=1	9031.ENSGALP00000012981	calpain 6	_	KOG0045	_	"PF00648.18|Peptidase_C2|Calpain family cysteine protease|ENSGALT00000012996|m.16532:27-341;PF01067.19|Calpain_III|Calpain large subunit, domain III|ENSGALT00000012996|m.16532:361-493;PF00168.27|C2|C2 domain|ENSGALT00000012996|m.16532:522-611"
ENSGALG00000008018	6.001758675	13.91246452	-1.211555613	3.29E-20	3.14E-19	down	yes	6.271319831	6.248186362	5.485769832	15.60967346	12.24714431	13.88057577	20	13790217	13793622	-	SNAI1	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0001755|neural crest cell migration; GO:0014029|neural crest formation; GO:0014036|neural crest cell fate specification; GO:0045892|negative regulation of transcription, DNA-templated"	GO:0005634|nucleus	GO:0003677|DNA binding; GO:0046872|metal ion binding	"ko:K05706|SNAI2,SLUG"	ko04390|Hippo signaling pathway; ko04520|Adherens junction	1756	XP_015737508.1	XP_015737508.1 PREDICTED: zinc finger protein SNAI1 isoform X1 [Coturnix japonica]	sp|P19382|SNAI1_XENLA	sp|P19382|SNAI1_XENLA Protein snail homolog Sna OS=Xenopus laevis GN=snai1 PE=1 SV=1	9031.ENSGALP00000012995	snail like protein 	COG5048	KOG2462	_	"PF00096.23|zf-C2H2|Zinc finger, C2H2 type|ENSGALT00000013010|m.3674:190-211;PF00096.23|zf-C2H2|Zinc finger, C2H2 type|ENSGALT00000013010|m.3674:217-239;PF13894.3|zf-C2H2_4|C2H2-type zinc finger|ENSGALT00000013010|m.3674:217-239;PF13912.3|zf-C2H2_6|C2H2-type zinc finger|ENSGALT00000013010|m.3674:163-185;PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000013010|m.3674:217-237"
ENSGALG00000008050	13.6591019	27.54282757	-1.011281925	5.17E-37	1.14E-35	down	yes	13.57636774	14.31808228	13.08285567	26.56521858	27.23933942	28.82392472	1	14682620	14697934	+	HBP1	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated; GO:0007050|cell cycle arrest; GO:0016055|Wnt signaling pathway"	GO:0005654|nucleoplasm; GO:0016607|nuclear speck	GO:0003677|DNA binding; GO:0003723|RNA binding	--	--	2709	XP_015131198.1	XP_015131198.1 HMG box-containing protein 1 isoform X1 [Gallus gallus]	sp|O60381|HBP1_HUMAN	sp|O60381|HBP1_HUMAN HMG box-containing protein 1 OS=Homo sapiens GN=HBP1 PE=1 SV=2	9031.ENSGALP00000013047	HMG-box transcription factor 1	_	KOG2746	_	PF08517.9|AXH|Ataxin-1 and HBP1 module (AXH)|ENSGALT00000013062|m.471:239-363;PF00505.16|HMG_box|HMG (high mobility group) box|ENSGALT00000013062|m.471:463-527;PF09011.7|HMG_box_2|HMG-box domain|ENSGALT00000013062|m.471:459-524
ENSGALG00000008056	38.23892256	13.2972726	1.523204196	4.38E-107	6.53E-105	up	yes	39.17558633	39.36517187	36.17600948	13.04308356	13.666841	13.18189323	20	13861021	13896307	+	B4GALT5	protein_coding	GO:0005975|carbohydrate metabolic process; GO:0016266|O-glycan processing; GO:0018146|keratan sulfate biosynthetic process	GO:0000139|Golgi membrane; GO:0016021|integral component of membrane; GO:0032580|Golgi cisterna membrane; GO:0070062|extracellular exosome	"GO:0003831|beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; GO:0008378|galactosyltransferase activity; GO:0046872|metal ion binding"	ko:K09905|B4GALT5	ko00512|Mucin type O-glycan biosynthesis	2698	XP_014731553.1	"XP_014731553.1 PREDICTED: LOW QUALITY PROTEIN: beta-1,4-galactosyltransferase 5 [Sturnus vulgaris]"	sp|O43286|B4GT5_HUMAN	"sp|O43286|B4GT5_HUMAN Beta-1,4-galactosyltransferase 5 OS=Homo sapiens GN=B4GALT5 PE=2 SV=1"	9031.ENSGALP00000013056	"UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5"	_	KOG3916	_	PF13733.3|Glyco_transf_7N|N-terminal region of glycosyl transferase group 7|ENSGALT00000095886|m.3684:316-450;PF02709.11|Glyco_transf_7C|N-terminal domain of galactosyltransferase|ENSGALT00000095886|m.3684:455-531
ENSGALG00000008077	1.438516107	6.358835623	-2.13645391	3.32E-23	3.75E-22	down	yes	1.606658296	1.151230456	1.55765957	6.812578116	6.556456308	5.707472446	10	19767468	19773275	+	ENSGALG00000008077	protein_coding	GO:0007275|multicellular organism development; GO:0048477|oogenesis; GO:0048545|response to steroid hormone	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0003707|steroid hormone receptor activity; GO:0005496|steroid binding	--	--	1443	XP_015147701.2	XP_015147701.2 membrane progestin receptor gamma [Gallus gallus]	sp|Q6DC77|MPRGB_DANRE	sp|Q6DC77|MPRGB_DANRE Membrane progestin receptor gamma-B OS=Danio rerio GN=paqr5b PE=2 SV=1	_	_	_	_	_	PF03006.17|HlyIII|Haemolysin-III related|ENSGALT00000013111|m.5892:15-203
ENSGALG00000008113	1.308819575	4.082285027	-1.633659426	4.56E-21	4.55E-20	down	yes	1.217118516	1.189856471	1.519483739	4.272957965	3.677100813	4.296796302	7	10323371	10366305	-	PLCL1	protein_coding	"GO:0006629|lipid metabolic process; GO:0007214|gamma-aminobutyric acid signaling pathway; GO:0032228|regulation of synaptic transmission, GABAergic; GO:0033135|regulation of peptidyl-serine phosphorylation; GO:0035556|intracellular signal transduction; GO:1900122|positive regulation of receptor binding"	GO:0005737|cytoplasm; GO:0005886|plasma membrane	"GO:0004435|phosphatidylinositol phospholipase C activity; GO:0004629|phospholipase C activity; GO:0050811|GABA receptor binding; GO:0070679|inositol 1,4,5 trisphosphate binding"	"ko:K15375|PLCL1,PRIP"	ko04727|GABAergic synapse	3117	XP_421916.3	XP_421916.3 inactive phospholipase C-like protein 1 [Gallus gallus]	sp|Q15111|PLCL1_HUMAN	sp|Q15111|PLCL1_HUMAN Inactive phospholipase C-like protein 1 OS=Homo sapiens GN=PLCL1 PE=1 SV=3	9031.ENSGALP00000013154	phospholipase C-like 1	_	KOG0169	_	"PF00388.16|PI-PLC-X|Phosphatidylinositol-specific phospholipase C, X domain|ENSGALT00000013169|m.5839:348-491;PF00387.16|PI-PLC-Y|Phosphatidylinositol-specific phospholipase C, Y domain|ENSGALT00000013169|m.5839:533-648;PF16457.2|PH_12|Pleckstrin homology domain|ENSGALT00000013169|m.5839:57-170;PF00168.27|C2|C2 domain|ENSGALT00000013169|m.5839:670-770;PF09279.8|EF-hand_like|Phosphoinositide-specific phospholipase C, efhand-like|ENSGALT00000013169|m.5839:258-339"
ENSGALG00000008123	7.270755074	16.84055559	-1.210636177	1.47E-31	2.53E-30	down	yes	6.17393975	8.305254819	7.333070654	16.82559708	16.25156414	17.44450554	1	14138452	14150312	+	RINT1	protein_coding	"GO:0006890|retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; GO:0007049|cell cycle; GO:0015031|protein transport; GO:0060628|regulation of ER to Golgi vesicle-mediated transport; GO:1902504|regulation of signal transduction involved in mitotic G2 DNA damage checkpoint"	GO:0005783|endoplasmic reticulum; GO:0005789|endoplasmic reticulum membrane; GO:0005829|cytosol; GO:0070939|Dsl1/NZR complex	--	"ko:K20474|RINT1,TIP20"	--	3098	NP_001265046.1	NP_001265046.1 RAD50-interacting protein 1 [Gallus gallus]	sp|Q6NUQ1|RINT1_HUMAN	sp|Q6NUQ1|RINT1_HUMAN RAD50-interacting protein 1 OS=Homo sapiens GN=RINT1 PE=1 SV=1	9031.ENSGALP00000013171	RAD50 interactor 1	_	KOG2218	_	PF04437.10|RINT1_TIP1|RINT-1 / TIP-1 family|ENSGALT00000013186|m.455:272-760
ENSGALG00000008135	0.898929457	2.744061833	-1.599320715	6.93E-18	5.65E-17	down	yes	0.950727291	0.784208335	0.961852745	2.749160302	2.79069305	2.692332148	7	10794292	10924557	-	SATB2	protein_coding	GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0001764|neuron migration; GO:0002076|osteoblast development; GO:0006338|chromatin remodeling; GO:0006357|regulation of transcription by RNA polymerase II; GO:0009880|embryonic pattern specification; GO:0016569|covalent chromatin modification; GO:0021902|commitment of neuronal cell to specific neuron type in forebrain; GO:0048704|embryonic skeletal system morphogenesis; GO:0051216|cartilage development; GO:0060021|roof of mouth development; GO:0071310|cellular response to organic substance	GO:0000118|histone deacetylase complex; GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005667|transcription factor complex; GO:0016363|nuclear matrix	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003682|chromatin binding; GO:0043565|sequence-specific DNA binding"	--	--	2907	XP_002191597.2	XP_002191597.2 PREDICTED: DNA-binding protein SATB2 [Taeniopygia guttata]	sp|Q9UPW6|SATB2_HUMAN	sp|Q9UPW6|SATB2_HUMAN DNA-binding protein SATB2 OS=Homo sapiens GN=SATB2 PE=1 SV=2	59729.ENSTGUP00000010818	DNA-binding protein SATB2 (Special AT-rich sequence-binding protein 2) [Taeniopygia guttata]	_	KOG3755	_	PF02376.12|CUT|CUT domain|ENSGALT00000045425|m.5840:356-434;PF02376.12|CUT|CUT domain|ENSGALT00000045425|m.5840:481-556;PF16557.2|CUTL|CUT1-like DNA-binding domain of SATB|ENSGALT00000045425|m.5840:163-233;PF16534.2|ULD|Ubiquitin-like oligomerisation domain of SATB|ENSGALT00000045425|m.5840:59-156;PF00046.26|Homeobox|Homeobox domain|ENSGALT00000045425|m.5840:614-669
ENSGALG00000008152	12.98541225	30.66981179	-1.239287232	2.08E-60	1.04E-58	down	yes	13.33273046	12.79319024	12.83031604	29.5115809	32.19909383	30.29876064	7	11092899	11169151	+	SPATS2L	protein_coding	--	GO:0005634|nucleus; GO:0005730|nucleolus; GO:0005829|cytosol; GO:0032991|protein-containing complex	GO:0003723|RNA binding	--	--	2875	XP_015144900.1	XP_015144900.1 SPATS2-like protein isoform X1 [Gallus gallus]	sp|Q9NUQ6|SPS2L_HUMAN	sp|Q9NUQ6|SPS2L_HUMAN SPATS2-like protein OS=Homo sapiens GN=SPATS2L PE=1 SV=2	9031.ENSGALP00000013227	hypothetical protein LOC424067 	_	_	NOG83093	PF07139.8|DUF1387|Protein of unknown function (DUF1387)|ENSGALT00000013241|m.5856:59-364
ENSGALG00000008164	0.453712016	1.748581514	-1.923111193	1.30E-23	1.50E-22	down	yes	0.560375573	0.434015342	0.366745133	1.617991829	1.944694421	1.683058293	10	20114123	20157777	+	ADAMTS7	protein_coding	GO:0032331|negative regulation of chondrocyte differentiation; GO:0036066|protein O-linked fucosylation; GO:0051603|proteolysis involved in cellular protein catabolic process; GO:0071347|cellular response to interleukin-1; GO:0071356|cellular response to tumor necrosis factor; GO:0071773|cellular response to BMP stimulus	GO:0005615|extracellular space; GO:0005788|endoplasmic reticulum lumen; GO:0009986|cell surface; GO:0031012|extracellular matrix	GO:0004222|metalloendopeptidase activity; GO:0008237|metallopeptidase activity; GO:0008270|zinc ion binding	ko:K08622|ADAMTS7	--	6051	XP_003641878.2	XP_003641878.2 A disintegrin and metalloproteinase with thrombospondin motifs 7 [Gallus gallus]	sp|Q9UKP4|ATS7_HUMAN	sp|Q9UKP4|ATS7_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 7 OS=Homo sapiens GN=ADAMTS7 PE=1 SV=2	9031.ENSGALP00000013251	annotation not avaliable	_	KOG3538	_	PF05986.11|ADAM_spacer1|ADAM-TS Spacer 1|ENSGALT00000100125|m.5923:681-791;PF01562.16|Pep_M12B_propep|Reprolysin family propeptide|ENSGALT00000100125|m.5923:24-164;PF01421.16|Reprolysin|Reprolysin (M12B) family zinc metalloprotease|ENSGALT00000100125|m.5923:224-434;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000100125|m.5923:524-574;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000100125|m.5923:809-861;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000100125|m.5923:868-924;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000100125|m.5923:931-976;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000100125|m.5923:1530-1575;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000100125|m.5923:1581-1604;PF13688.3|Reprolysin_5|Metallo-peptidase family M12|ENSGALT00000100125|m.5923:223-400;PF13582.3|Reprolysin_3|Metallo-peptidase family M12B Reprolysin-like|ENSGALT00000100125|m.5923:249-381
ENSGALG00000008178	0.286394551	0.821186816	-1.487653844	0.002226466	0.004437583	down	yes	0.323258215	0.289682805	0.246242634	0.837640612	0.823905742	0.802014095	9	15837337	15842611	-	CYP2AB2	protein_coding	GO:0006690|icosanoid metabolic process; GO:0006805|xenobiotic metabolic process; GO:0008016|regulation of heart contraction; GO:0019373|epoxygenase P450 pathway; GO:0043651|linoleic acid metabolic process	GO:0005789|endoplasmic reticulum membrane; GO:0031090|organelle membrane; GO:0070062|extracellular exosome	"GO:0004497|monooxygenase activity; GO:0005506|iron ion binding; GO:0008392|arachidonic acid epoxygenase activity; GO:0008404|arachidonic acid 14,15-epoxygenase activity; GO:0008405|arachidonic acid 11,12-epoxygenase activity; GO:0020037|heme binding; GO:0070330|aromatase activity; GO:0071614|linoleic acid epoxygenase activity"	ko:K17857|CYP2P	--	1467	NP_001316414.1	"NP_001316414.1 cytochrome P450, family 2, subfamily AB, polypeptide 2 precursor [Gallus gallus]"	sp|P51589|CP2J2_HUMAN	sp|P51589|CP2J2_HUMAN Cytochrome P450 2J2 OS=Homo sapiens GN=CYP2J2 PE=1 SV=2	9031.ENSGALP00000013290	hypothetical protein LOC770119	COG2124	KOG0156	_	PF00067.19|p450|Cytochrome P450|ENSGALT00000013305|m.9061:29-484
ENSGALG00000008182	5.645251085	2.623606267	1.102551406	4.27E-16	3.09E-15	up	yes	5.027186294	6.327735462	5.580831501	2.478263939	2.761812828	2.630742033	3	3044379	3055276	-	CHAC2	protein_coding	GO:0006751|glutathione catabolic process	GO:0005737|cytoplasm; GO:0005829|cytosol	GO:0003839|gamma-glutamylcyclotransferase activity; GO:0016829|lyase activity	--	--	3071	NP_001026203.2	NP_001026203.2 putative glutathione-specific gamma-glutamylcyclotransferase 2 [Gallus gallus]	sp|Q5ZI66|CHAC2_CHICK	sp|Q5ZI66|CHAC2_CHICK Putative glutathione-specific gamma-glutamylcyclotransferase 2 OS=Gallus gallus GN=chac2 PE=2 SV=1	_	_	_	_	_	PF04752.9|ChaC|ChaC-like protein|ENSGALT00000013322|m.10606:19-191
ENSGALG00000008185	5.786487305	13.46411243	-1.216939451	7.54E-39	1.78E-37	down	yes	5.602957166	5.388907295	6.367597453	12.7766703	13.75628436	13.85938261	7	11196756	11233011	+	AOX1	protein_coding	GO:0009115|xanthine catabolic process; GO:0017144|drug metabolic process; GO:0042816|vitamin B6 metabolic process; GO:0055114|oxidation-reduction process	GO:0005829|cytosol; GO:0016604|nuclear body; GO:0070062|extracellular exosome	"GO:0004031|aldehyde oxidase activity; GO:0005506|iron ion binding; GO:0009055|electron transfer activity; GO:0016614|oxidoreductase activity, acting on CH-OH group of donors; GO:0016903|oxidoreductase activity, acting on the aldehyde or oxo group of donors; GO:0042802|identical protein binding; GO:0042803|protein homodimerization activity; GO:0043546|molybdopterin cofactor binding; GO:0050660|flavin adenine dinucleotide binding; GO:0051287|NAD binding; GO:0051537|2 iron, 2 sulfur cluster binding; GO:0102797|geranial:oxygen oxidoreductase activity; GO:0102798|heptaldehyde:oxygen oxidoreductase activity"	ko:K00157|AOX	"ko00280|Valine, leucine and isoleucine degradation; ko00350|Tyrosine metabolism; ko00380|Tryptophan metabolism; ko00750|Vitamin B6 metabolism; ko00760|Nicotinate and nicotinamide metabolism; ko00830|Retinol metabolism; ko00982|Drug metabolism - cytochrome P450; ko01100|Metabolic pathways; ko01120|Microbial metabolism in diverse environments; ko04630|Jak-STAT signaling pathway"	4072	XP_015144903.1	XP_015144903.1 aldehyde oxidase isoform X2 [Gallus gallus]	sp|Q06278|AOXA_HUMAN	sp|Q06278|AOXA_HUMAN Aldehyde oxidase OS=Homo sapiens GN=AOX1 PE=1 SV=2	9031.ENSGALP00000013312	aldehyde oxidase 1 	COG4630;COG4631	KOG0430	_	"PF02738.15|Ald_Xan_dh_C2|Molybdopterin-binding domain of aldehyde dehydrogenase|ENSGALT00000013327|m.5862:720-1247;PF00941.18|FAD_binding_5|FAD binding domain in molybdopterin dehydrogenase|ENSGALT00000013327|m.5862:243-420;PF01315.19|Ald_Xan_dh_C|Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain|ENSGALT00000013327|m.5862:596-702;PF01799.17|Fer2_2|[2Fe-2S] binding domain|ENSGALT00000013327|m.5862:93-167;PF03450.14|CO_deh_flav_C|CO dehydrogenase flavoprotein C-terminal domain|ENSGALT00000013327|m.5862:428-532;PF00111.24|Fer2|2Fe-2S iron-sulfur cluster binding domain|ENSGALT00000013327|m.5862:15-82"
ENSGALG00000008269	41.43118435	95.15442768	-1.199357163	9.40E-71	6.28E-69	down	yes	44.92505172	40.78104024	38.58746108	95.378405	98.61653218	91.46834588	3	3236158	3265532	+	ZC3H6	protein_coding	--	--	GO:0046872|metal ion binding	--	--	5360	NP_001186379.1	NP_001186379.1 zinc finger CCCH domain-containing protein 6 [Gallus gallus]	sp|P61129|ZC3H6_HUMAN	sp|P61129|ZC3H6_HUMAN Zinc finger CCCH domain-containing protein 6 OS=Homo sapiens GN=ZC3H6 PE=1 SV=2	9031.ENSGALP00000013443	zinc finger CCCH-type containing 6	_	KOG1040	_	"PF00642.21|zf-CCCH|Zinc finger C-x8-C-x5-C-x3-H type (and similar)|ENSGALT00000013458|m.10628:283-306;PF14608.3|zf-CCCH_2|RNA-binding, Nab2-type zinc finger|ENSGALT00000013458|m.10628:286-305;PF14608.3|zf-CCCH_2|RNA-binding, Nab2-type zinc finger|ENSGALT00000013458|m.10628:315-334;PF14608.3|zf-CCCH_2|RNA-binding, Nab2-type zinc finger|ENSGALT00000013458|m.10628:338-358"
ENSGALG00000008288	4.548747812	9.730190544	-1.095312393	3.23E-11	1.59E-10	down	yes	3.601857395	5.009513758	5.034872283	8.701653805	10.45628105	10.03263678	1	13055479	13063032	+	ARMC10	protein_coding	GO:0040010|positive regulation of growth rate; GO:0043066|negative regulation of apoptotic process; GO:1902254|negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator	GO:0005739|mitochondrion; GO:0005783|endoplasmic reticulum; GO:0005789|endoplasmic reticulum membrane; GO:0016021|integral component of membrane	GO:0002039|p53 binding; GO:0050692|DBD domain binding	--	--	1419	XP_415964.3	XP_415964.3 armadillo repeat-containing protein 10 isoform X1 [Gallus gallus]	sp|B1WBW4|ARM10_RAT	sp|B1WBW4|ARM10_RAT Armadillo repeat-containing protein 10 OS=Rattus norvegicus GN=Armc10 PE=1 SV=1	9031.ENSGALP00000013472	armadillo repeat containing 10	_	_	NOG18524	PF04826.10|Arm_2|Armadillo-like|ENSGALT00000013487|m.432:49-295
ENSGALG00000008308	11.21514241	26.41138054	-1.234972103	6.97E-32	1.21E-30	down	yes	13.04404812	10.01134167	10.59003743	27.37307774	23.61466736	28.24639652	12	18986975	18991321	+	BHLHE40	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0045892|negative regulation of transcription, DNA-templated; GO:0048511|rhythmic process"	GO:0005634|nucleus; GO:0005737|cytoplasm	GO:0003714|transcription corepressor activity; GO:0046983|protein dimerization activity; GO:0070888|E-box binding	"ko:K03729|BHLHB2,DEC1"	ko04710|Circadian rhythm	2763	NP_001264073.1	NP_001264073.1 class E basic helix-loop-helix protein 40 [Gallus gallus]	sp|B3F209|BHE40_SHEEP	sp|B3F209|BHE40_SHEEP Class E basic helix-loop-helix protein 40 OS=Ovis aries GN=BHLHE40 PE=2 SV=1	9031.ENSGALP00000013509	"basic helix-loop-helix domain containing, class B, 2"	_	KOG4304	_	PF00010.23|HLH|Helix-loop-helix DNA-binding domain|ENSGALT00000073347|m.8085:57-107;PF07527.10|Hairy_orange|Hairy Orange|ENSGALT00000073347|m.8085:141-178
ENSGALG00000008326	2.817016804	9.246413147	-1.7111728	2.52E-49	8.86E-48	down	yes	2.957711862	2.811144138	2.682194412	8.817893448	9.067220098	9.854125896	4	14162384	14186992	+	ENSGALG00000008326	protein_coding	GO:0006886|intracellular protein transport; GO:0006887|exocytosis; GO:0006904|vesicle docking involved in exocytosis; GO:0006906|vesicle fusion; GO:0010923|negative regulation of phosphatase activity; GO:0016192|vesicle-mediated transport; GO:0070257|positive regulation of mucus secretion; GO:0072659|protein localization to plasma membrane	GO:0005737|cytoplasm; GO:0005886|plasma membrane; GO:0016020|membrane; GO:0019897|extrinsic component of plasma membrane; GO:0042470|melanosome; GO:0070382|exocytic vesicle	"GO:0001786|phosphatidylserine binding; GO:0005509|calcium ion binding; GO:0005544|calcium-dependent phospholipid binding; GO:0005546|phosphatidylinositol-4,5-bisphosphate binding; GO:0017137|Rab GTPase binding; GO:0019902|phosphatase binding; GO:0019905|syntaxin binding; GO:0030276|clathrin binding; GO:0042043|neurexin family protein binding"	ko:K17598|SYTL	--	3367	XP_004940873.1	XP_004940873.1 synaptotagmin-like protein 2 [Gallus gallus]	sp|Q9HCH5|SYTL2_HUMAN	sp|Q9HCH5|SYTL2_HUMAN Synaptotagmin-like protein 2 OS=Homo sapiens GN=SYTL2 PE=1 SV=3	_	_	_	_	_	PF00168.27|C2|C2 domain|ENSGALT00000052692|m.16560:682-789;PF00168.27|C2|C2 domain|ENSGALT00000052692|m.16560:827-930;PF02318.13|FYVE_2|FYVE-type zinc finger|ENSGALT00000052692|m.16560:6-52
ENSGALG00000008349	1.107501312	3.015554211	-1.436922909	3.84E-08	1.43E-07	down	yes	1.456449023	0.830565313	1.0354896	2.860945676	2.969704479	3.216012477	12	19629856	19651438	+	LMCD1	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006351|transcription, DNA-templated; GO:0010611|regulation of cardiac muscle hypertrophy; GO:0044267|cellular protein metabolic process; GO:0070886|positive regulation of calcineurin-NFAT signaling cascade"	GO:0005615|extracellular space; GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm	GO:0003714|transcription corepressor activity; GO:0008270|zinc ion binding	--	--	1628	XP_414443.4	XP_414443.4 LIM and cysteine-rich domains protein 1 [Gallus gallus]	sp|Q9NZU5|LMCD1_HUMAN	sp|Q9NZU5|LMCD1_HUMAN LIM and cysteine-rich domains protein 1 OS=Homo sapiens GN=LMCD1 PE=1 SV=1	9031.ENSGALP00000013575	LIM and cysteine-rich domains 1	_	KOG1704	_	PF06297.11|PET|PET Domain|ENSGALT00000013590|m.8097:120-203;PF00412.19|LIM|LIM domain|ENSGALT00000013590|m.8097:246-305;PF00412.19|LIM|LIM domain|ENSGALT00000013590|m.8097:311-364
ENSGALG00000008354	11.37446587	27.74307451	-1.285580998	9.61E-22	9.96E-21	down	yes	11.95803759	9.114647907	13.05071213	32.3760636	23.6468008	27.20635915	5	23739312	23743460	+	HARBI1	protein_coding	--	GO:0005634|nucleus; GO:0005815|microtubule organizing center; GO:0005829|cytosol; GO:0005886|plasma membrane	GO:0004518|nuclease activity; GO:0046872|metal ion binding	--	--	1670	XP_015142731.1	XP_015142731.1 putative nuclease HARBI1 [Gallus gallus]	sp|Q17QR8|HARB1_BOVIN	sp|Q17QR8|HARB1_BOVIN Putative nuclease HARBI1 OS=Bos taurus GN=HARBI1 PE=2 SV=1	9031.ENSGALP00000013590	chromosome 11 open reading frame 77	_	KOG4585	_	PF13359.3|DDE_Tnp_4|DDE superfamily endonuclease|ENSGALT00000013605|m.3003:219-371;PF04827.11|Plant_tran|Plant transposon protein|ENSGALT00000013605|m.3003:209-374
ENSGALG00000008411	1.44650607	0.70475823	1.026984482	0.020680396	0.034300785	up	yes	1.705607509	1.473865926	1.160044777	0.549909578	0.770927469	0.793437643	12	19849378	19852107	-	GHRL	protein_coding	GO:0001696|gastric acid secretion; GO:0007204|positive regulation of cytosolic calcium ion concentration; GO:0009755|hormone-mediated signaling pathway; GO:0016358|dendrite development; GO:0032024|positive regulation of insulin secretion; GO:0032095|regulation of response to food; GO:0032097|positive regulation of response to food; GO:0046676|negative regulation of insulin secretion; GO:0050728|negative regulation of inflammatory response; GO:0051965|positive regulation of synapse assembly; GO:0060124|positive regulation of growth hormone secretion; GO:0061098|positive regulation of protein tyrosine kinase activity	GO:0005576|extracellular region; GO:0005623|cell	GO:0005179|hormone activity; GO:0016608|growth hormone-releasing hormone activity; GO:0031768|ghrelin receptor binding	ko:K05254|GHRL	ko04024|cAMP signaling pathway	865	BAC24980.1	BAC24980.1 ghrelin [Gallus gallus]	sp|Q6BEG6|GHRL_FELCA	sp|Q6BEG6|GHRL_FELCA Appetite-regulating hormone OS=Felis catus GN=GHRL PE=1 SV=1	9031.ENSGALP00000013685	ghrelin preproprotein 	_	_	NOG45924	PF04643.9|Motilin_assoc|Motilin/ghrelin-associated peptide|ENSGALT00000013700|m.8125:56-114
ENSGALG00000008415	2.149584296	5.562818923	-1.367653646	1.08E-22	1.18E-21	down	yes	1.764421561	2.564249495	2.120081833	4.953926801	6.176557903	5.557972064	7	11545922	11578947	-	ALS2	protein_coding	"GO:0001662|behavioral fear response; GO:0001701|in utero embryonic development; GO:0001881|receptor recycling; GO:0006979|response to oxidative stress; GO:0007032|endosome organization; GO:0007409|axonogenesis; GO:0007528|neuromuscular junction development; GO:0007626|locomotory behavior; GO:0008104|protein localization; GO:0008219|cell death; GO:0016197|endosomal transport; GO:0016601|Rac protein signal transduction; GO:0035022|positive regulation of Rac protein signal transduction; GO:0035023|regulation of Rho protein signal transduction; GO:0035249|synaptic transmission, glutamatergic; GO:0043547|positive regulation of GTPase activity; GO:0045860|positive regulation of protein kinase activity; GO:0048812|neuron projection morphogenesis; GO:0051036|regulation of endosome size; GO:0061024|membrane organization"	GO:0001726|ruffle; GO:0005769|early endosome; GO:0005813|centrosome; GO:0005829|cytosol; GO:0014069|postsynaptic density; GO:0016020|membrane; GO:0030027|lamellipodium; GO:0030424|axon; GO:0030425|dendrite; GO:0030426|growth cone; GO:0031982|vesicle; GO:0032991|protein-containing complex; GO:0043025|neuronal cell body; GO:0043197|dendritic spine; GO:0043231|intracellular membrane-bounded organelle	GO:0017112|Rab guanyl-nucleotide exchange factor activity; GO:0017137|Rab GTPase binding; GO:0030676|Rac guanyl-nucleotide exchange factor activity; GO:0042803|protein homodimerization activity; GO:0043539|protein serine/threonine kinase activator activity	ko:K04575|ALS2	ko05014|Amyotrophic lateral sclerosis (ALS)	5017	XP_421940.2	XP_421940.2 alsin isoform X1 [Gallus gallus]	sp|Q96Q42|ALS2_HUMAN	sp|Q96Q42|ALS2_HUMAN Alsin OS=Homo sapiens GN=ALS2 PE=1 SV=2	9031.ENSGALP00000013692	amyotrophic lateral sclerosis 2 (juvenile)	COG4642;COG5184	KOG0231;KOG1426	_	PF00415.15|RCC1|Regulator of chromosome condensation (RCC1) repeat|ENSGALT00000013707|m.5897:110-165;PF00415.15|RCC1|Regulator of chromosome condensation (RCC1) repeat|ENSGALT00000013707|m.5897:171-216;PF00415.15|RCC1|Regulator of chromosome condensation (RCC1) repeat|ENSGALT00000013707|m.5897:522-569;PF00415.15|RCC1|Regulator of chromosome condensation (RCC1) repeat|ENSGALT00000013707|m.5897:574-619;PF13540.3|RCC1_2|Regulator of chromosome condensation (RCC1) repeat|ENSGALT00000013707|m.5897:93-122;PF13540.3|RCC1_2|Regulator of chromosome condensation (RCC1) repeat|ENSGALT00000013707|m.5897:556-585;PF02493.17|MORN|MORN repeat|ENSGALT00000013707|m.5897:1041-1061;PF02493.17|MORN|MORN repeat|ENSGALT00000013707|m.5897:1064-1080;PF02493.17|MORN|MORN repeat|ENSGALT00000013707|m.5897:1092-1113;PF02493.17|MORN|MORN repeat|ENSGALT00000013707|m.5897:1115-1131;PF02493.17|MORN|MORN repeat|ENSGALT00000013707|m.5897:1143-1158;PF02493.17|MORN|MORN repeat|ENSGALT00000013707|m.5897:1167-1181;PF02493.17|MORN|MORN repeat|ENSGALT00000013707|m.5897:1213-1235;PF02204.15|VPS9|Vacuolar sorting protein 9 (VPS9) domain|ENSGALT00000013707|m.5897:1546-1645;PF00621.17|RhoGEF|RhoGEF domain|ENSGALT00000013707|m.5897:687-872
ENSGALG00000008440	0.328673231	2.03767916	-2.596023821	7.67E-14	4.69E-13	down	yes	0.346126406	0.234258629	0.405634657	2.303446828	1.590050079	2.219540573	5	24229253	24231231	+	CHST1	protein_coding	GO:0005976|polysaccharide metabolic process; GO:0006012|galactose metabolic process; GO:0006790|sulfur compound metabolic process; GO:0006954|inflammatory response; GO:0018146|keratan sulfate biosynthetic process; GO:0042339|keratan sulfate metabolic process	GO:0000139|Golgi membrane; GO:0016021|integral component of membrane	GO:0001517|N-acetylglucosamine 6-O-sulfotransferase activity; GO:0008146|sulfotransferase activity; GO:0045130|keratan sulfotransferase activity	ko:K01022|CHST1	ko00533|Glycosaminoglycan biosynthesis - keratan sulfate	1979	XP_015142632.1	XP_015142632.1 carbohydrate sulfotransferase 1 [Gallus gallus]	sp|O43916|CHST1_HUMAN	sp|O43916|CHST1_HUMAN Carbohydrate sulfotransferase 1 OS=Homo sapiens GN=CHST1 PE=1 SV=1	9031.ENSGALP00000013735	carbohydrate (keratan sulfate Gal-6) sulfotransferase 1	_	_	NOG80862	PF00685.24|Sulfotransfer_1|Sulfotransferase domain|ENSGALT00000013750|m.3042:67-391;PF13469.3|Sulfotransfer_3|Sulfotransferase family|ENSGALT00000013750|m.3042:235-332
ENSGALG00000008442	0.08737674	0.400260362	-2.074890668	4.77E-10	2.13E-09	down	yes	0.083493925	0.061217818	0.117418477	0.386536474	0.391178267	0.423066345	4	15290397	15521568	+	TENM1	protein_coding	"GO:0000902|cell morphogenesis; GO:0006351|transcription, DNA-templated; GO:0006359|regulation of transcription by RNA polymerase III; GO:0007157|heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; GO:0007218|neuropeptide signaling pathway; GO:0030838|positive regulation of actin filament polymerization; GO:0033138|positive regulation of peptidyl-serine phosphorylation; GO:0043406|positive regulation of MAP kinase activity; GO:0048666|neuron development; GO:0051491|positive regulation of filopodium assembly; GO:0090316|positive regulation of intracellular protein transport"	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005783|endoplasmic reticulum; GO:0005794|Golgi apparatus; GO:0005856|cytoskeleton; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0016363|nuclear matrix; GO:0016607|nuclear speck; GO:0043005|neuron projection; GO:0048471|perinuclear region of cytoplasm	GO:0042803|protein homodimerization activity; GO:0046982|protein heterodimerization activity; GO:0050839|cell adhesion molecule binding	--	--	8204	XP_015133675.1	XP_015133675.1 teneurin-1 isoform X1 [Gallus gallus]	sp|Q9W6V6|TEN1_CHICK	sp|Q9W6V6|TEN1_CHICK Teneurin-1 OS=Gallus gallus GN=TENM1 PE=1 SV=1	9031.ENSGALP00000031671	Teneurin-1 (Ten-1)(Tenascin-M1)(Ten-m1)(Protein Odd Oz/ten-m homolog 1); May function as a c [...] 	_	KOG4659	_	PF06484.9|Ten_N|Teneurin Intracellular Region|ENSGALT00000076797|m.16574:17-162;PF06484.9|Ten_N|Teneurin Intracellular Region|ENSGALT00000076797|m.16574:161-298;PF15636.3|Tox-GHH|GHH signature containing HNH/Endo VII superfamily nuclease toxin|ENSGALT00000076797|m.16574:2629-2706;PF12661.4|hEGF|Human growth factor-like EGF|ENSGALT00000076797|m.16574:721-733
ENSGALG00000008447	1.370378167	0.377962675	1.831073796	2.04E-05	5.51E-05	up	yes	1.462446555	0.977655283	1.671032663	0.307406936	0.442299969	0.384181119	4	15530219	15544105	-	SH2D1A	protein_coding	GO:0002250|adaptive immune response; GO:0006959|humoral immune response; GO:0006968|cellular defense response; GO:0007267|cell-cell signaling; GO:0045087|innate immune response; GO:0045954|positive regulation of natural killer cell mediated cytotoxicity	GO:0005737|cytoplasm	GO:0005070|SH3/SH2 adaptor activity	"ko:K07990|SH2D1A,SAP"	ko04650|Natural killer cell mediated cytotoxicity; ko05162|Measles	1225	XP_021262032.1	XP_021262032.1 SH2 domain-containing protein 1A [Numida meleagris]	sp|Q3ZBB1|SH21A_BOVIN	sp|Q3ZBB1|SH21A_BOVIN SH2 domain-containing protein 1A OS=Bos taurus GN=SH2D1A PE=2 SV=1	9031.ENSGALP00000013748	stromal antigen 2	_	KOG0565	_	PF00017.21|SH2|SH2 domain|ENSGALT00000013763|m.16581:49-127
ENSGALG00000008457	18.39568845	79.93408325	-2.118839549	3.37E-187	2.55E-184	down	yes	18.50791883	17.76207596	18.91707055	75.72259724	86.80681126	77.27284125	3	4154797	4182140	+	RIN2	protein_coding	GO:0006897|endocytosis; GO:0007264|small GTPase mediated signal transduction; GO:0061024|membrane organization	GO:0005829|cytosol	GO:0005096|GTPase activator activity; GO:0017112|Rab guanyl-nucleotide exchange factor activity; GO:0030695|GTPase regulator activity	--	--	2410	XP_004940217.1	XP_004940217.1 ras and Rab interactor 2 isoform X2 [Gallus gallus]	sp|Q8WYP3|RIN2_HUMAN	sp|Q8WYP3|RIN2_HUMAN Ras and Rab interactor 2 OS=Homo sapiens GN=RIN2 PE=1 SV=1	_	_	_	_	_	_
ENSGALG00000008475	7.506123938	18.07034659	-1.266361573	4.06E-37	9.05E-36	down	yes	8.386694505	7.096149868	7.035527441	16.95119818	19.36261969	17.89722192	17	2324755	2351466	+	ARRDC1	protein_coding	GO:0006511|ubiquitin-dependent protein catabolic process; GO:0006858|extracellular transport; GO:0008104|protein localization; GO:0015031|protein transport; GO:0016567|protein ubiquitination; GO:0045746|negative regulation of Notch signaling pathway	GO:0005886|plasma membrane; GO:0031410|cytoplasmic vesicle; GO:0070062|extracellular exosome; GO:1903561|extracellular vesicle	"GO:0031625|ubiquitin protein ligase binding; GO:0042802|identical protein binding; GO:1990756|protein binding, bridging involved in substrate recognition for ubiquitination; GO:1990763|arrestin family protein binding"	--	--	2978	NP_001026646.1	NP_001026646.1 arrestin domain-containing protein 1 [Gallus gallus]	sp|Q99KN1|ARRD1_MOUSE	sp|Q99KN1|ARRD1_MOUSE Arrestin domain-containing protein 1 OS=Mus musculus GN=Arrdc1 PE=1 SV=2	9031.ENSGALP00000013796	arrestin domain containing 1 	_	KOG3780	_	"PF02752.19|Arrestin_C|Arrestin (or S-antigen), C-terminal domain|ENSGALT00000013811|m.11806:186-307;PF00339.26|Arrestin_N|Arrestin (or S-antigen), N-terminal domain|ENSGALT00000013811|m.11806:30-162;PF03643.12|Vps26|Vacuolar protein sorting-associated protein 26|ENSGALT00000013811|m.11806:36-155"
ENSGALG00000008490	0.115191107	0.590948853	-2.263110125	1.78E-05	4.86E-05	down	yes	0.131563269	0.080385252	0.1336248	0.758805039	0.589704975	0.424336546	12	20107152	20111710	+	TRH	protein_coding	GO:0001692|histamine metabolic process; GO:0007165|signal transduction; GO:0009755|hormone-mediated signaling pathway; GO:0014050|negative regulation of glutamate secretion; GO:0014054|positive regulation of gamma-aminobutyric acid secretion; GO:0032024|positive regulation of insulin secretion; GO:0042755|eating behavior	GO:0005576|extracellular region; GO:0005634|nucleus; GO:0005886|plasma membrane; GO:0030141|secretory granule	GO:0008437|thyrotropin-releasing hormone activity	ko:K05253|TRH	--	2403	NP_001025554.1	NP_001025554.1 thyrotropin releasing hormone preproprotein [Gallus gallus]	sp|Q6ZXC3|TRH_CHICK	sp|Q6ZXC3|TRH_CHICK Pro-thyrotropin-releasing hormone OS=Gallus gallus GN=TRH PE=2 SV=2	9031.ENSGALP00000013820	Prothyroliberin Precursor [Contains Thyroliberin(Thyrotropin-releasing hormone)(TRH)(Thyrotr [...] 	_	_	NOG45849	PF05438.9|TRH|Thyrotropin-releasing hormone (TRH)|ENSGALT00000013835|m.8159:8-226
ENSGALG00000008501	1.9993548	8.483420878	-2.079613413	1.96E-53	8.02E-52	down	yes	2.219151334	1.976704973	1.802208095	8.650835628	8.711381454	8.088045552	7	12266170	12321029	+	KLF7	protein_coding	"GO:0007409|axonogenesis; GO:0007411|axon guidance; GO:0045893|positive regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0048813|dendrite morphogenesis"	GO:0005634|nucleus	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity; GO:0046872|metal ion binding"	ko:K09207|KLF6_7	--	2873	NP_001305919.1	NP_001305919.1 Krueppel-like factor 7 [Gallus gallus]	sp|Q99JB0|KLF7_MOUSE	sp|Q99JB0|KLF7_MOUSE Krueppel-like factor 7 OS=Mus musculus GN=Klf7 PE=2 SV=1	59729.ENSTGUP00000010334	Krueppel-like factor 7 (Ubiquitous krueppel-like factor) [Taeniopygia guttata]	COG5048	KOG1721	_	_
ENSGALG00000008513	25.67435604	11.50540482	1.157324773	5.41E-27	7.44E-26	up	yes	26.87136753	24.46145913	25.69024145	12.98576334	11.05779192	10.4726592	4	16382396	16384100	+	C1GALT1C1	protein_coding	"GO:0006493|protein O-linked glycosylation; GO:0016266|O-glycan processing; GO:0016267|O-glycan processing, core 1; GO:0030168|platelet activation; GO:0036344|platelet morphogenesis"	GO:0000139|Golgi membrane; GO:0016021|integral component of membrane; GO:0070062|extracellular exosome	GO:0016263|glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity	"ko:K09653|C1GALT2,C1GALT1C1"	ko00512|Mucin type O-glycan biosynthesis; ko01100|Metabolic pathways	1453	NP_001264718.1	NP_001264718.1 C1GALT1-specific chaperone 1 [Gallus gallus]	sp|Q96EU7|C1GLC_HUMAN	sp|Q96EU7|C1GLC_HUMAN C1GALT1-specific chaperone 1 OS=Homo sapiens GN=C1GALT1C1 PE=1 SV=1	9031.ENSGALP00000013850	C1GALT1-specific chaperone 1	_	KOG2246	_	_
ENSGALG00000008525	29.04989475	14.45102482	1.006859681	5.19E-31	8.62E-30	up	yes	28.34636602	30.29762309	28.50569514	15.44258045	12.58824027	15.32225374	3	4209087	4236900	-	ABHD12	protein_coding	GO:0006660|phosphatidylserine catabolic process; GO:0007628|adult walking behavior; GO:0010996|response to auditory stimulus; GO:0046464|acylglycerol catabolic process; GO:0052651|monoacylglycerol catabolic process	GO:0016021|integral component of membrane; GO:0032281|AMPA glutamate receptor complex	GO:0004622|lysophospholipase activity; GO:0047372|acylglycerol lipase activity	ko:K13704|ABHD12	--	3147	NP_001012889.1	NP_001012889.1 monoacylglycerol lipase ABHD12 [Gallus gallus]	sp|Q5ZIN0|ABD12_CHICK	sp|Q5ZIN0|ABD12_CHICK Monoacylglycerol lipase ABHD12 OS=Gallus gallus GN=ABHD12 PE=2 SV=1	9031.ENSGALP00000013877	Monoacylglycerol lipase ABHD12 (EC 3.1.1.23)(2-arachidonoylglycerol hydrolase)(Abhydrolase d [...] 	COG1073	KOG1552	_	"PF12146.5|Hydrolase_4|Serine aminopeptidase, S33|ENSGALT00000013893|m.10663:189-307;PF00561.17|Abhydrolase_1|alpha/beta hydrolase fold|ENSGALT00000013893|m.10663:189-278;PF12697.4|Abhydrolase_6|Alpha/beta hydrolase family|ENSGALT00000013893|m.10663:192-307"
ENSGALG00000008548	0.466607424	0.979834213	-1.054385485	0.013273755	0.022902582	down	yes	0.61880316	0.521763067	0.259256043	0.896132497	1.260382099	0.782988041	7	12390869	12399996	+	MDH1B	protein_coding	GO:0005975|carbohydrate metabolic process; GO:0006099|tricarboxylic acid cycle; GO:0006107|oxaloacetate metabolic process; GO:0006108|malate metabolic process; GO:0006734|NADH metabolic process	GO:0005737|cytoplasm	GO:0030060|L-malate dehydrogenase activity	--	--	1703	XP_421952.1	XP_421952.1 putative malate dehydrogenase 1B isoform X1 [Gallus gallus]	sp|Q5I0G3|MDH1B_HUMAN	sp|Q5I0G3|MDH1B_HUMAN Putative malate dehydrogenase 1B OS=Homo sapiens GN=MDH1B PE=2 SV=1	9031.ENSGALP00000013910	"malate dehydrogenase 1B, NAD (soluble)"	COG0039	KOG1496	_	"PF02866.15|Ldh_1_C|lactate/malate dehydrogenase, alpha/beta C-terminal domain|ENSGALT00000013926|m.5929:391-470"
ENSGALG00000008586	221.0400671	70.74242889	1.643521591	3.37E-140	1.13E-137	up	yes	223.7228676	225.3391089	214.0582247	75.59065287	70.63883132	65.99780247	17	2241348	2243444	-	TUBB4B	protein_coding	GO:0007017|microtubule-based process	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005874|microtubule; GO:0031012|extracellular matrix; GO:0043209|myelin sheath; GO:0070062|extracellular exosome	GO:0003725|double-stranded RNA binding; GO:0003924|GTPase activity; GO:0005200|structural constituent of cytoskeleton; GO:0005525|GTP binding	ko:K07375|TUBB	ko04145|Phagosome; ko04540|Gap junction; ko05130|Pathogenic Escherichia coli infection	1537	XP_007945164.1	XP_007945164.1 PREDICTED: tubulin beta-4B chain isoform X1 [Orycteropus afer afer]	sp|Q3MHM5|TBB4B_BOVIN	sp|Q3MHM5|TBB4B_BOVIN Tubulin beta-4B chain OS=Bos taurus GN=TUBB4B PE=2 SV=1	_	_	_	_	_	"PF00091.22|Tubulin|Tubulin/FtsZ family, GTPase domain|ENSGALT00000013980|m.11797:3-211;PF03953.14|Tubulin_C|Tubulin C-terminal domain|ENSGALT00000013980|m.11797:261-381"
ENSGALG00000008591	7.277001798	15.08367154	-1.050546532	2.82E-25	3.58E-24	down	yes	7.346691443	6.426842717	8.057471234	14.53054084	14.21127769	16.50919608	2	19119896	19343839	-	CACNB2	protein_coding	GO:0007268|chemical synaptic transmission; GO:0007528|neuromuscular junction development; GO:0007601|visual perception; GO:0051928|positive regulation of calcium ion transport; GO:0061337|cardiac conduction; GO:0070509|calcium ion import; GO:0072659|protein localization to plasma membrane; GO:0086045|membrane depolarization during AV node cell action potential; GO:0086091|regulation of heart rate by cardiac conduction; GO:0098912|membrane depolarization during atrial cardiac muscle cell action potential; GO:1901385|regulation of voltage-gated calcium channel activity; GO:1901843|positive regulation of high voltage-gated calcium channel activity; GO:1904879|positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0005891|voltage-gated calcium channel complex; GO:1990454|L-type voltage-gated calcium channel complex	GO:0005245|voltage-gated calcium channel activity; GO:0005262|calcium channel activity; GO:0051015|actin filament binding	ko:K04863|CACNB2	ko04010|MAPK signaling pathway; ko04260|Cardiac muscle contraction; ko04261|Adrenergic signaling in cardiomyocytes; ko04921|Oxytocin signaling pathway; ko05410|Hypertrophic cardiomyopathy (HCM); ko05412|Arrhythmogenic right ventricular cardiomyopathy (ARVC); ko05414|Dilated cardiomyopathy	3421	XP_015137498.1	XP_015137498.1 voltage-dependent L-type calcium channel subunit beta-2 isoform X2 [Gallus gallus]	sp|Q08289|CACB2_HUMAN	sp|Q08289|CACB2_HUMAN Voltage-dependent L-type calcium channel subunit beta-2 OS=Homo sapiens GN=CACNB2 PE=1 SV=3	9031.ENSGALP00000013972	"calcium channel, voltage-dependent, beta 2 subunit"	_	KOG3812	_	PF00625.18|Guanylate_kin|Guanylate kinase|ENSGALT00000013988|m.15010:272-452;PF12052.5|VGCC_beta4Aa_N|Voltage gated calcium channel subunit beta domain 4Aa N terminal|ENSGALT00000013988|m.15010:64-105
ENSGALG00000008599	0.563412236	1.681736585	-1.560860354	0.000211997	0.000494796	down	yes	0.580495049	0.327399596	0.782342062	2.082743691	1.483463716	1.479002348	5	24874554	24881577	+	ENSGALG00000008599	protein_coding	GO:0006790|sulfur compound metabolic process; GO:0016051|carbohydrate biosynthetic process	GO:0000139|Golgi membrane; GO:0016021|integral component of membrane	GO:0001537|N-acetylgalactosamine 4-O-sulfotransferase activity	--	--	1180	XP_004941676.1	XP_004941676.1 carbohydrate sulfotransferase 9 [Gallus gallus]	sp|Q76EC5|CHST9_MOUSE	sp|Q76EC5|CHST9_MOUSE Carbohydrate sulfotransferase 9 OS=Mus musculus GN=Chst9 PE=2 SV=1	_	_	_	_	_	PF03567.11|Sulfotransfer_2|Sulfotransferase family|ENSGALT00000014001|m.3078:77-304
ENSGALG00000008608	5.691289413	15.82930768	-1.474149134	6.28E-20	5.89E-19	down	yes	4.026860451	6.796315184	6.250692604	17.13321527	16.06130738	14.29340037	9	16303131	16310398	+	FETUB	protein_coding	GO:0007338|single fertilization; GO:0007339|binding of sperm to zona pellucida; GO:0010951|negative regulation of endopeptidase activity	GO:0005576|extracellular region; GO:0070062|extracellular exosome	GO:0004869|cysteine-type endopeptidase inhibitor activity; GO:0008191|metalloendopeptidase inhibitor activity	--	--	1387	NP_001264337.1	NP_001264337.1 fetuin-B precursor [Gallus gallus]	sp|Q58D62|FETUB_BOVIN	sp|Q58D62|FETUB_BOVIN Fetuin-B OS=Bos taurus GN=FETUB PE=1 SV=1	9031.ENSGALP00000014003	Apo AI promoter B-region binding protein Fragment 	_	_	NOG87310	PF00031.18|Cystatin|Cystatin domain|ENSGALT00000039765|m.9150:37-122;PF00031.18|Cystatin|Cystatin domain|ENSGALT00000039765|m.9150:157-243;PF00666.14|Cathelicidins|Cathelicidin|ENSGALT00000039765|m.9150:162-259
ENSGALG00000008661	3.94582864	17.30192695	-2.12971448	4.87E-45	1.50E-43	down	yes	3.273101486	4.735400254	3.828984179	20.3473025	16.52798692	15.03049144	8	16587842	16590293	-	CYR61	protein_coding	"GO:0001558|regulation of cell growth; GO:0001649|osteoblast differentiation; GO:0002041|intussusceptive angiogenesis; GO:0003181|atrioventricular valve morphogenesis; GO:0003278|apoptotic process involved in heart morphogenesis; GO:0003281|ventricular septum development; GO:0007155|cell adhesion; GO:0007165|signal transduction; GO:0007267|cell-cell signaling; GO:0010518|positive regulation of phospholipase activity; GO:0010811|positive regulation of cell-substrate adhesion; GO:0030198|extracellular matrix organization; GO:0030335|positive regulation of cell migration; GO:0030513|positive regulation of BMP signaling pathway; GO:0033690|positive regulation of osteoblast proliferation; GO:0043066|negative regulation of apoptotic process; GO:0043280|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0044319|wound healing, spreading of cells; GO:0045669|positive regulation of osteoblast differentiation; GO:0045860|positive regulation of protein kinase activity; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0060413|atrial septum morphogenesis; GO:0060548|negative regulation of cell death; GO:0060591|chondroblast differentiation; GO:0061036|positive regulation of cartilage development; GO:0070372|regulation of ERK1 and ERK2 cascade; GO:0072593|reactive oxygen species metabolic process; GO:0098609|cell-cell adhesion; GO:2000304|positive regulation of ceramide biosynthetic process"	GO:0005615|extracellular space; GO:0031012|extracellular matrix	GO:0005178|integrin binding; GO:0005520|insulin-like growth factor binding; GO:0008201|heparin binding; GO:0050840|extracellular matrix binding	ko:K06829|CYR61	--	1803	NP_001026734.1	NP_001026734.1 protein CYR61 precursor [Gallus gallus]	sp|P19336|CYR61_CHICK	sp|P19336|CYR61_CHICK Protein CYR61 OS=Gallus gallus GN=CYR61 PE=2 SV=1	_	_	_	_	_	PF00007.19|Cys_knot|Cystine-knot domain|ENSGALT00000014106|m.7562:279-367;PF00093.15|VWC|von Willebrand factor type C domain|ENSGALT00000014106|m.7562:100-163;PF00219.15|IGFBP|Insulin-like growth factor binding protein|ENSGALT00000014106|m.7562:26-78;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000014106|m.7562:228-267
ENSGALG00000008684	371.5532608	152.4576326	1.285104854	3.67E-71	2.51E-69	up	yes	373.7356686	372.1297585	368.7943553	170.9701364	137.2252026	149.1775586	9	16355099	16361974	+	EIF4A2	protein_coding	GO:0006413|translational initiation; GO:0010468|regulation of gene expression; GO:0010501|RNA secondary structure unwinding	GO:0005730|nucleolus; GO:0005737|cytoplasm	GO:0003724|RNA helicase activity; GO:0003743|translation initiation factor activity; GO:0005524|ATP binding	ko:K03257|EIF4A	ko03013|RNA transport	2061	NP_989880.1	NP_989880.1 eukaryotic initiation factor 4A-II [Gallus gallus]	sp|Q8JFP1|IF4A2_CHICK	sp|Q8JFP1|IF4A2_CHICK Eukaryotic initiation factor 4A-II OS=Gallus gallus GN=EIF4A2 PE=2 SV=1	_	_	_	_	_	"PF00270.26|DEAD|DEAD/DEAH box helicase|ENSGALT00000055728|m.9161:118-282;PF00271.28|Helicase_C|Helicase conserved C-terminal domain|ENSGALT00000055728|m.9161:320-428;PF04851.12|ResIII|Type III restriction enzyme, res subunit|ENSGALT00000055728|m.9161:133-278"
ENSGALG00000008709	0.860652483	0.347316078	1.284896159	0.000116663	0.000282946	up	yes	0.705441976	0.994674364	0.88184111	0.251742992	0.386307309	0.403897932	8	16765732	16781321	+	MCOLN3	protein_coding	GO:0007626|locomotory behavior; GO:0042491|inner ear auditory receptor cell differentiation; GO:0070588|calcium ion transmembrane transport	GO:0000421|autophagosome membrane; GO:0005765|lysosomal membrane; GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0031901|early endosome membrane; GO:0031902|late endosome membrane	GO:0005262|calcium channel activity	ko:K04994|MCOLN3	--	2402	XP_019474215.1	XP_019474215.1 PREDICTED: mucolipin-3 [Meleagris gallopavo]	sp|Q8TDD5|MCLN3_HUMAN	sp|Q8TDD5|MCLN3_HUMAN Mucolipin-3 OS=Homo sapiens GN=MCOLN3 PE=1 SV=1	_	_	_	_	_	PF08016.9|PKD_channel|Polycystin cation channel|ENSGALT00000014171|m.7580:371-508
ENSGALG00000008725	7.979623868	16.73276039	-1.067337914	3.76E-64	2.11E-62	down	yes	7.826033241	7.951783983	8.16105438	16.43197673	17.15484148	16.61146296	3	5496073	5630444	-	KIF16B	protein_coding	GO:0001704|formation of primary germ layer; GO:0001919|regulation of receptor recycling; GO:0006895|Golgi to endosome transport; GO:0007018|microtubule-based movement; GO:0007173|epidermal growth factor receptor signaling pathway; GO:0007492|endoderm development; GO:0008543|fibroblast growth factor receptor signaling pathway; GO:0032801|receptor catabolic process; GO:0045022|early endosome to late endosome transport	GO:0005768|endosome; GO:0005769|early endosome; GO:0005829|cytosol; GO:0005871|kinesin complex; GO:0005874|microtubule; GO:0031901|early endosome membrane	"GO:0005524|ATP binding; GO:0005547|phosphatidylinositol-3,4,5-trisphosphate binding; GO:0008017|microtubule binding; GO:0008574|ATP-dependent microtubule motor activity, plus-end-directed; GO:0017137|Rab GTPase binding; GO:0032266|phosphatidylinositol-3-phosphate binding; GO:0043325|phosphatidylinositol-3,4-bisphosphate binding; GO:0080025|phosphatidylinositol-3,5-bisphosphate binding"	"ko:K17916|KIF16B,SNX23"	--	6548	XP_015712215.1	XP_015712215.1 PREDICTED: kinesin-like protein KIF16B isoform X1 [Coturnix japonica]	sp|Q96L93|KI16B_HUMAN	sp|Q96L93|KI16B_HUMAN Kinesin-like protein KIF16B OS=Homo sapiens GN=KIF16B PE=1 SV=2	_	_	_	_	_	PF00225.20|Kinesin|Kinesin motor domain|ENSGALT00000093775|m.10705:162-511;PF16796.2|Microtub_bd|Microtubule binding|ENSGALT00000093775|m.10705:156-315
ENSGALG00000008731	0.419458845	1.237390517	-1.538321405	6.56E-07	2.14E-06	down	yes	0.468455759	0.433073605	0.356847172	1.218138993	1.159967211	1.334065347	3	15499040	15539871	+	DZANK1	protein_coding	--	--	GO:0046872|metal ion binding	--	--	2446	NP_001186325.1	NP_001186325.1 double zinc ribbon and ankyrin repeat-containing protein 1 [Gallus gallus]	sp|Q9NVP4|DZAN1_HUMAN	sp|Q9NVP4|DZAN1_HUMAN Double zinc ribbon and ankyrin repeat-containing protein 1 OS=Homo sapiens GN=DZANK1 PE=1 SV=3	9031.ENSGALP00000014193	annotation not avaliable	_	_	NOG72667	PF12773.4|DZR|Double zinc ribbon|ENSGALT00000014209|m.10959:350-398;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000014209|m.10959:640-726;PF13287.3|Fn3_assoc|Fn3 associated|ENSGALT00000014209|m.10959:41-93;PF13290.3|CHB_HEX_C_1|Chitobiase/beta-hexosaminidase C-terminal domain|ENSGALT00000014209|m.10959:41-90
ENSGALG00000008740	11.21719345	25.78217541	-1.19993613	8.64E-47	2.80E-45	down	yes	11.0289619	11.29103772	11.33158073	23.15578248	28.12752268	26.06322108	1	21884126	21946881	+	POT1	protein_coding	GO:0000723|telomere maintenance; GO:0007004|telomere maintenance via telomerase; GO:0016233|telomere capping; GO:0032210|regulation of telomere maintenance via telomerase; GO:0051974|negative regulation of telomerase activity	"GO:0000781|chromosome, telomeric region; GO:0000783|nuclear telomere cap complex; GO:0005654|nucleoplasm"	GO:0010521|telomerase inhibitor activity; GO:0043047|single-stranded telomeric DNA binding; GO:0098505|G-rich strand telomeric DNA binding	ko:K11109|POT1	--	4123	XP_015136397.2	XP_015136397.2 protection of telomeres protein 1 isoform X1 [Gallus gallus]	sp|P62597|POTE1_CHICK	sp|P62597|POTE1_CHICK Protection of telomeres protein 1 OS=Gallus gallus GN=POT1 PE=1 SV=1	9031.ENSGALP00000014206	Protection of telomeres protein 1 (cPot1)(POT1-like telomere end-binding protein); Component [...] 	_	KOG4757	_	PF16686.2|POT1PC|ssDNA-binding domain of telomere protection protein|ENSGALT00000030716|m.605:367-510;PF02765.14|POT1|Telomeric single stranded DNA binding POT1/CDC13|ENSGALT00000030716|m.605:225-354
ENSGALG00000008744	0.717918586	1.775441341	-1.294431729	7.38E-18	6.01E-17	down	yes	0.727530995	0.699493053	0.726731711	1.768459753	1.856710574	1.701153695	9	16375392	16527556	+	MCF2L2	protein_coding	GO:0007266|Rho protein signal transduction; GO:0035025|positive regulation of Rho protein signal transduction; GO:0045944|positive regulation of transcription by RNA polymerase II	GO:0005615|extracellular space; GO:0005737|cytoplasm; GO:0012505|endomembrane system; GO:0016020|membrane; GO:0019898|extrinsic component of membrane; GO:0030027|lamellipodium; GO:0031234|extrinsic component of cytoplasmic side of plasma membrane	GO:0005089|Rho guanyl-nucleotide exchange factor activity; GO:0005545|1-phosphatidylinositol binding; GO:0035091|phosphatidylinositol binding	"ko:K20685|MCF2,ARHGEF14_21_22"	--	7574	XP_025009203.1	XP_025009203.1 probable guanine nucleotide exchange factor MCF2L2 isoform X6 [Gallus gallus]	sp|Q64096|MCF2L_MOUSE	sp|Q64096|MCF2L_MOUSE Guanine nucleotide exchange factor DBS OS=Mus musculus GN=Mcf2l PE=1 SV=2	13616.ENSMODP00000026612	MCF.2 cell line derived transforming sequence-like 2	_	KOG4240	_	PF00621.17|RhoGEF|RhoGEF domain|ENSGALT00000061761|m.9163:613-787;PF00169.26|PH|PH domain|ENSGALT00000061761|m.9163:821-922;PF13716.3|CRAL_TRIO_2|Divergent CRAL/TRIO domain|ENSGALT00000061761|m.9163:62-181
ENSGALG00000008745	5.924359976	15.11281797	-1.349562647	1.07E-39	2.60E-38	down	yes	5.766113467	6.0576278	5.949338663	15.52229623	14.2104338	15.60572387	3	11969797	11992290	+	APLF	protein_coding	GO:0000012|single strand break repair; GO:0006302|double-strand break repair; GO:0006974|cellular response to DNA damage stimulus; GO:0045191|regulation of isotype switching; GO:0051106|positive regulation of DNA ligation	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005829|cytosol; GO:0035861|site of double-strand break	GO:0000166|nucleotide binding; GO:0003906|DNA-(apurinic or apyrimidinic site) endonuclease activity; GO:0004520|endodeoxyribonuclease activity; GO:0008408|3'-5' exonuclease activity; GO:0046872|metal ion binding; GO:0140078|class I DNA-(apurinic or apyrimidinic site) endonuclease activity; GO:0140080|class III/IV DNA-(apurinic or apyrimidinic site) endonuclease activity	ko:K13295|APLF	--	2385	XP_419335.3	XP_419335.3 aprataxin and PNK-like factor isoform X1 [Gallus gallus]	sp|Q8IW19|APLF_HUMAN	sp|Q8IW19|APLF_HUMAN Aprataxin and PNK-like factor OS=Homo sapiens GN=APLF PE=1 SV=1	9031.ENSGALP00000014218	chromosome 2 open reading frame 13	_	_	NOG85452	PF10283.6|zf-CCHH|Zinc-finger (CX5CX6HX5H) motif|ENSGALT00000014234|m.10882:386-409;PF10283.6|zf-CCHH|Zinc-finger (CX5CX6HX5H) motif|ENSGALT00000014234|m.10882:427-449
ENSGALG00000008747	0.870041562	2.931932206	-1.741120436	7.03E-15	4.65E-14	down	yes	0.788863739	1.239419097	0.58184185	2.599917075	3.441824511	2.754055031	2	20336331	20435530	+	ITGA8	protein_coding	GO:0007155|cell adhesion; GO:0007229|integrin-mediated signaling pathway; GO:0007399|nervous system development; GO:0030154|cell differentiation	GO:0008305|integrin complex	GO:0046872|metal ion binding	ko:K06584|ITGA8	ko04151|PI3K-Akt signaling pathway; ko04510|Focal adhesion; ko04512|ECM-receptor interaction; ko04514|Cell adhesion molecules (CAMs); ko04810|Regulation of actin cytoskeleton; ko05410|Hypertrophic cardiomyopathy (HCM); ko05412|Arrhythmogenic right ventricular cardiomyopathy (ARVC); ko05414|Dilated cardiomyopathy	3823	NP_990619.1	NP_990619.1 integrin alpha-8 precursor [Gallus gallus]	sp|P26009|ITA8_CHICK	sp|P26009|ITA8_CHICK Integrin alpha-8 OS=Gallus gallus GN=ITGA8 PE=1 SV=1	9031.ENSGALP00000014220	Integrin alpha-8 Precursor [Contains Integrin alpha-8 heavy chain;Integrin alpha-8 light cha [...] 	_	KOG3637	_	"PF08441.9|Integrin_alpha2|Integrin alpha|ENSGALT00000014236|m.15055:490-940;PF01839.20|FG-GAP|FG-GAP repeat|ENSGALT00000014236|m.15055:328-370;PF01839.20|FG-GAP|FG-GAP repeat|ENSGALT00000014236|m.15055:399-429;PF13517.3|VCBS|Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella|ENSGALT00000014236|m.15055:336-413;PF00357.17|Integrin_alpha|Integrin alpha cytoplasmic region|ENSGALT00000014236|m.15055:1041-1055"
ENSGALG00000008771	11.49125247	24.73863786	-1.105558146	7.94E-06	2.26E-05	down	yes	11.4978837	11.68287767	11.29299604	29.37617221	16.89151386	27.94822751	6	27122877	27178543	+	SHOC2	protein_coding	GO:0007265|Ras protein signal transduction; GO:0046579|positive regulation of Ras protein signal transduction	GO:0000164|protein phosphatase type 1 complex; GO:0005634|nucleus; GO:0005737|cytoplasm	GO:0019888|protein phosphatase regulator activity; GO:0019903|protein phosphatase binding	"ko:K19613|SHOC2,SUR8"	ko04014|Ras signaling pathway	4656	XP_015144138.1	XP_015144138.1 leucine-rich repeat protein SHOC-2 isoform X1 [Gallus gallus]	sp|Q5F4C4|SHOC2_CHICK	sp|Q5F4C4|SHOC2_CHICK Leucine-rich repeat protein SHOC-2 OS=Gallus gallus GN=SHOC2 PE=2 SV=1	9031.ENSGALP00000014251	soc-2 suppressor of clear homolog ; Regulatory subunit of protein phosphatase 1 (PP1c) that  [...] 	COG4886	KOG0619	_	PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000014266|m.5286:124-181;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000014266|m.5286:217-273;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000014266|m.5286:284-341;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000014266|m.5286:404-460;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000014266|m.5286:448-506;PF12799.4|LRR_4|Leucine Rich repeats (2 copies)|ENSGALT00000014266|m.5286:426-464;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000014266|m.5286:259-342;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000014266|m.5286:303-389
ENSGALG00000008814	0.52575631	1.075555033	-1.018784025	0.009680087	0.017162801	down	yes	0.596824634	0.395916879	0.584527417	1.30420617	0.674405604	1.248053325	1	22434929	22445383	-	ASB15	protein_coding	GO:0035556|intracellular signal transduction	GO:0000151|ubiquitin ligase complex; GO:0005634|nucleus; GO:0005737|cytoplasm	GO:0004842|ubiquitin-protein transferase activity; GO:0031625|ubiquitin protein ligase binding	ko:K10337|ASB15	--	1854	XP_415996.2	XP_415996.2 ankyrin repeat and SOCS box protein 15 [Gallus gallus]	sp|Q8HXA6|ASB15_BOVIN	sp|Q8HXA6|ASB15_BOVIN Ankyrin repeat and SOCS box protein 15 OS=Bos taurus GN=ASB15 PE=2 SV=2	9031.ENSGALP00000014312	ankyrin repeat and SOCS box-containing 15	COG0666	KOG0504	_	PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000014328|m.622:105-173;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000014328|m.622:144-209;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000014328|m.622:176-239;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000014328|m.622:217-298;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000014328|m.622:249-338;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000014328|m.622:315-409;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000014328|m.622:115-166;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000014328|m.622:180-231;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000014328|m.622:246-298;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000014328|m.622:146-172;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000014328|m.622:180-206;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000014328|m.622:211-239;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000014328|m.622:181-209;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000014328|m.622:386-409;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000014328|m.622:198-246;PF07525.13|SOCS_box|SOCS box|ENSGALT00000014328|m.622:536-577
ENSGALG00000008819	5.275376542	11.36231338	-1.105447599	4.27E-20	4.03E-19	down	yes	5.229019759	4.728503589	5.868606278	10.88343757	12.87021555	10.33328702	17	1900196	1925313	-	LRSAM1	protein_coding	GO:0000209|protein polyubiquitination; GO:0006914|autophagy; GO:0007165|signal transduction; GO:0030163|protein catabolic process; GO:0045806|negative regulation of endocytosis; GO:0046755|viral budding; GO:0051865|protein autoubiquitination; GO:0070086|ubiquitin-dependent endocytosis; GO:1904417|positive regulation of xenophagy; GO:2000786|positive regulation of autophagosome assembly	GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0016020|membrane	GO:0004842|ubiquitin-protein transferase activity; GO:0046872|metal ion binding; GO:0061630|ubiquitin protein ligase activity	ko:K10641|LRSAM1	--	3023	XP_415540.3	XP_415540.3 E3 ubiquitin-protein ligase LRSAM1 isoform X1 [Gallus gallus]	sp|Q80ZI6|LRSM1_MOUSE	sp|Q80ZI6|LRSM1_MOUSE E3 ubiquitin-protein ligase LRSAM1 OS=Mus musculus GN=Lrsam1 PE=1 SV=1	9031.ENSGALP00000014318	leucine rich repeat and sterile alpha motif containing 1	COG4886	KOG0619	_	"PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000076180|m.11760:83-139;PF13920.3|zf-C3HC4_3|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000076180|m.11760:677-720;PF00536.27|SAM_1|SAM domain (Sterile alpha motif)|ENSGALT00000076180|m.11760:573-627;PF07647.14|SAM_2|SAM domain (Sterile alpha motif)|ENSGALT00000076180|m.11760:575-629"
ENSGALG00000008881	0.059535987	0.357223385	-2.400826212	0.00039218	0.000879494	down	yes	0	0.058029519	0.120578443	0.364687656	0.375620875	0.331361625	17	1734410	1747726	-	RGS3	protein_coding	GO:0000188|inactivation of MAPK activity; GO:0008277|regulation of G protein-coupled receptor signaling pathway	GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005886|plasma membrane	GO:0005096|GTPase activator activity	ko:K07524|RGS3	ko04360|Axon guidance	2234	AAM94022.1	"AAM94022.1 regulator of G protein signaling 3, partial [Gallus gallus]"	sp|P49796|RGS3_HUMAN	sp|P49796|RGS3_HUMAN Regulator of G-protein signaling 3 OS=Homo sapiens GN=RGS3 PE=1 SV=2	9031.ENSGALP00000014417	regulator of G-protein signalling 3 RGS3L isoform 	_	KOG3589	_	PF00615.16|RGS|Regulator of G protein signaling domain|ENSGALT00000056621|m.11735:316-430
ENSGALG00000008883	11.81826653	25.20875538	-1.092258419	4.68E-42	1.29E-40	down	yes	11.64105457	11.43022206	12.38352295	25.35584633	26.97240774	23.29801208	6	28006744	28178462	+	TCF7L2	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0001568|blood vessel development; GO:0006351|transcription, DNA-templated; GO:0006357|regulation of transcription by RNA polymerase II; GO:0007050|cell cycle arrest; GO:0007223|Wnt signaling pathway, calcium modulating pathway; GO:0008283|cell population proliferation; GO:0009749|response to glucose; GO:0010909|positive regulation of heparan sulfate proteoglycan biosynthetic process; GO:0031016|pancreas development; GO:0032024|positive regulation of insulin secretion; GO:0032092|positive regulation of protein binding; GO:0032350|regulation of hormone metabolic process; GO:0042593|glucose homeostasis; GO:0043433|negative regulation of DNA-binding transcription factor activity; GO:0043570|maintenance of DNA repeat elements; GO:0044334|canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition; GO:0045444|fat cell differentiation; GO:0045892|negative regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0046827|positive regulation of protein export from nucleus; GO:0048625|myoblast fate commitment; GO:0048660|regulation of smooth muscle cell proliferation; GO:0051897|positive regulation of protein kinase B signaling; GO:0060070|canonical Wnt signaling pathway; GO:0090090|negative regulation of canonical Wnt signaling pathway; GO:1904837|beta-catenin-TCF complex assembly; GO:2000675|negative regulation of type B pancreatic cell apoptotic process; GO:2001237|negative regulation of extrinsic apoptotic signaling pathway"	GO:0000790|nuclear chromatin; GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0016605|PML body; GO:0032993|protein-DNA complex; GO:0070369|beta-catenin-TCF7L2 complex	GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0001103|RNA polymerase II repressing transcription factor binding; GO:0003700|DNA-binding transcription factor activity; GO:0008013|beta-catenin binding; GO:0008134|transcription factor binding; GO:0019901|protein kinase binding; GO:0035257|nuclear hormone receptor binding; GO:0043565|sequence-specific DNA binding; GO:0044212|transcription regulatory region DNA binding; GO:0045295|gamma-catenin binding; GO:0070016|armadillo repeat domain binding	ko:K04491|TCF7L2	ko04310|Wnt signaling pathway; ko04390|Hippo signaling pathway; ko04520|Adherens junction; ko04916|Melanogenesis; ko05200|Pathways in cancer; ko05210|Colorectal cancer; ko05213|Endometrial cancer; ko05215|Prostate cancer; ko05216|Thyroid cancer; ko05217|Basal cell carcinoma; ko05221|Acute myeloid leukemia; ko05224|Breast cancer; ko05412|Arrhythmogenic right ventricular cardiomyopathy (ARVC)	3797	NP_001193439.1	NP_001193439.1 transcription factor 7-like 2 [Gallus gallus]	sp|Q9NQB0|TF7L2_HUMAN	sp|Q9NQB0|TF7L2_HUMAN Transcription factor 7-like 2 OS=Homo sapiens GN=TCF7L2 PE=1 SV=2	_	_	_	_	_	PF08347.8|CTNNB1_binding|N-terminal CTNNB1 binding|ENSGALT00000014436|m.5298:1-236;PF00505.16|HMG_box|HMG (high mobility group) box|ENSGALT00000014436|m.5298:327-394;PF09011.7|HMG_box_2|HMG-box domain|ENSGALT00000014436|m.5298:328-385
ENSGALG00000008912	3.626367243	7.652387549	-1.075296089	1.46E-16	1.09E-15	down	yes	3.496476592	3.676508835	3.706116303	6.973583266	9.154639771	6.828939612	2	20665075	20706383	-	ABCB1	protein_coding	GO:0032376|positive regulation of cholesterol transport; GO:0032782|bile acid secretion; GO:0055088|lipid homeostasis; GO:0061092|positive regulation of phospholipid translocation; GO:1901557|response to fenofibrate; GO:1903413|cellular response to bile acid; GO:2001140|positive regulation of phospholipid transport	GO:0005737|cytoplasm; GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0016324|apical plasma membrane; GO:0030136|clathrin-coated vesicle; GO:0045121|membrane raft	GO:0005524|ATP binding; GO:0008525|phosphatidylcholine transporter activity; GO:0008559|ATPase-coupled xenobiotic transmembrane transporter activity; GO:0042626|ATPase-coupled transmembrane transporter activity; GO:0090554|phosphatidylcholine floppase activity	ko:K05659|ABCB4	ko02010|ABC transporters; ko04976|Bile secretion	3888	XP_025004168.1	XP_025004168.1 multidrug resistance protein 1 isoform X1 [Gallus gallus]	sp|P23174|MDR3_CRIGR	sp|P23174|MDR3_CRIGR Phosphatidylcholine translocator ABCB4 OS=Cricetulus griseus GN=ABCB4 PE=2 SV=1	9031.ENSGALP00000037453	"ATP-binding cassette, sub-family B (MDR/TAP), member 1"	COG1132	KOG0055	_	PF00664.20|ABC_membrane|ABC transporter transmembrane region|ENSGALT00000070008|m.15067:64-362;PF00664.20|ABC_membrane|ABC transporter transmembrane region|ENSGALT00000070008|m.15067:728-1001;PF00005.24|ABC_tran|ABC transporter|ENSGALT00000070008|m.15067:429-578;PF00005.24|ABC_tran|ABC transporter|ENSGALT00000070008|m.15067:1068-1219
ENSGALG00000008914	0.316305381	0.68036648	-1.081139639	6.81E-05	0.000170927	down	yes	0.313456872	0.296550776	0.338908495	0.638975723	0.739827218	0.662296498	6	28407511	28452857	-	NRAP	protein_coding	--	GO:0005916|fascia adherens; GO:0005927|muscle tendon junction	GO:0003779|actin binding; GO:0046872|metal ion binding; GO:0051371|muscle alpha-actinin binding	--	--	5211	XP_003641574.1	XP_003641574.1 nebulin-related-anchoring protein isoform X1 [Gallus gallus]	sp|Q86VF7|NRAP_HUMAN	sp|Q86VF7|NRAP_HUMAN Nebulin-related-anchoring protein OS=Homo sapiens GN=NRAP PE=1 SV=2	_	_	_	_	_	PF00880.15|Nebulin|Nebulin repeat|ENSGALT00000014498|m.5305:210-238;PF00880.15|Nebulin|Nebulin repeat|ENSGALT00000014498|m.5305:247-275;PF00880.15|Nebulin|Nebulin repeat|ENSGALT00000014498|m.5305:317-344;PF00880.15|Nebulin|Nebulin repeat|ENSGALT00000014498|m.5305:495-522;PF00880.15|Nebulin|Nebulin repeat|ENSGALT00000014498|m.5305:529-557;PF00880.15|Nebulin|Nebulin repeat|ENSGALT00000014498|m.5305:568-593;PF00880.15|Nebulin|Nebulin repeat|ENSGALT00000014498|m.5305:603-627;PF00880.15|Nebulin|Nebulin repeat|ENSGALT00000014498|m.5305:768-795;PF00880.15|Nebulin|Nebulin repeat|ENSGALT00000014498|m.5305:808-832;PF00880.15|Nebulin|Nebulin repeat|ENSGALT00000014498|m.5305:846-869;PF00880.15|Nebulin|Nebulin repeat|ENSGALT00000014498|m.5305:1011-1038;PF00880.15|Nebulin|Nebulin repeat|ENSGALT00000014498|m.5305:1047-1075;PF00880.15|Nebulin|Nebulin repeat|ENSGALT00000014498|m.5305:1089-1113;PF00880.15|Nebulin|Nebulin repeat|ENSGALT00000014498|m.5305:1256-1277;PF00880.15|Nebulin|Nebulin repeat|ENSGALT00000014498|m.5305:1497-1525;PF00880.15|Nebulin|Nebulin repeat|ENSGALT00000014498|m.5305:1608-1627;PF00880.15|Nebulin|Nebulin repeat|ENSGALT00000014498|m.5305:1636-1665;PF00412.19|LIM|LIM domain|ENSGALT00000014498|m.5305:6-57
ENSGALG00000008918	3.327148729	1.249476524	1.405791755	4.08E-09	1.67E-08	up	yes	3.865731304	2.439265285	3.6764496	1.242584142	0.945127426	1.560718002	3	14045653	14055302	-	LAMP5	protein_coding	--	GO:0005886|plasma membrane; GO:0010008|endosome membrane; GO:0016021|integral component of membrane; GO:0030054|cell junction; GO:0030659|cytoplasmic vesicle membrane; GO:0030672|synaptic vesicle membrane; GO:0031901|early endosome membrane; GO:0032584|growth cone membrane; GO:0032590|dendrite membrane; GO:0033116|endoplasmic reticulum-Golgi intermediate compartment membrane; GO:0055038|recycling endosome membrane	--	--	--	2051	XP_015139017.1	XP_015139017.1 lysosome-associated membrane glycoprotein 5 [Gallus gallus]	sp|Q9UJQ1|LAMP5_HUMAN	sp|Q9UJQ1|LAMP5_HUMAN Lysosome-associated membrane glycoprotein 5 OS=Homo sapiens GN=LAMP5 PE=1 SV=1	9031.ENSGALP00000014483	chromosome 20 open reading frame 103	_	_	NOG41798	PF01299.14|Lamp|Lysosome-associated membrane glycoprotein (Lamp)|ENSGALT00000087622|m.10928:104-326
ENSGALG00000008925	26.74759005	10.39688043	1.362410513	2.26E-11	1.13E-10	up	yes	31.40953	22.46550705	26.3677331	13.55066622	8.670296276	8.969678803	17	1312991	1313401	-	TMEM203	protein_coding	GO:0006874|cellular calcium ion homeostasis; GO:0007283|spermatogenesis	GO:0005783|endoplasmic reticulum; GO:0005789|endoplasmic reticulum membrane; GO:0016021|integral component of membrane	--	--	--	411	XP_003211219.1	XP_003211219.1 PREDICTED: transmembrane protein 203 [Meleagris gallopavo]	sp|Q8R235|TM203_MOUSE	sp|Q8R235|TM203_MOUSE Transmembrane protein 203 OS=Mus musculus GN=Tmem203 PE=2 SV=1	9031.ENSGALP00000039603	transmembrane protein 203	_	KOG3631	_	PF10269.6|Tmemb_185A|Transmembrane Fragile-X-F protein|ENSGALT00000014506|m.11712:14-124
ENSGALG00000008937	11.66600882	30.78897242	-1.399335011	8.40E-91	8.60E-89	down	yes	12.14769966	11.08370626	11.76662055	31.19202838	31.15152172	30.02336715	3	9563168	9592601	+	PPP1R21	protein_coding	--	--	GO:0019902|phosphatase binding	"ko:K17562|PPP1R21,CCDC128,KLRAQ1"	--	3570	NP_001012891.1	NP_001012891.1 protein phosphatase 1 regulatory subunit 21 [Gallus gallus]	sp|Q5ZL12|PPR21_CHICK	sp|Q5ZL12|PPR21_CHICK Protein phosphatase 1 regulatory subunit 21 OS=Gallus gallus GN=PPP1R21 PE=2 SV=1	_	_	_	_	_	PF10212.6|TTKRSYEDQ|Predicted coiled-coil domain-containing protein|ENSGALT00000014523|m.10805:280-794;PF10205.6|KLRAQ|Predicted coiled-coil domain-containing protein|ENSGALT00000014523|m.10805:36-136
ENSGALG00000008940	1.174279247	2.979435827	-1.33586394	1.52E-30	2.47E-29	down	yes	1.121367695	1.2993791	1.102090946	2.742529834	3.323617381	2.872160266	5	25427166	25520280	-	ENSGALG00000008940	protein_coding	GO:0000165|MAPK cascade; GO:0006888|endoplasmic reticulum to Golgi vesicle-mediated transport; GO:0007030|Golgi organization; GO:0007041|lysosomal transport; GO:0007411|axon guidance; GO:0030036|actin cytoskeleton organization; GO:0051260|protein homooligomerization; GO:0051693|actin filament capping	GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0008091|spectrin; GO:0016020|membrane; GO:0032391|photoreceptor connecting cilium; GO:0070062|extracellular exosome; GO:0097381|photoreceptor disc membrane	GO:0003779|actin binding; GO:0005088|Ras guanyl-nucleotide exchange factor activity; GO:0019894|kinesin binding; GO:0030507|spectrin binding; GO:0032029|myosin tail binding; GO:0034452|dynactin binding; GO:0043621|protein self-association; GO:0045505|dynein intermediate chain binding	ko:K06115|SPTB	--	11982	XP_025007067.1	"XP_025007067.1 spectrin beta chain, non-erythrocytic 5, partial [Gallus gallus]"	sp|Q9NRC6|SPTN5_HUMAN	"sp|Q9NRC6|SPTN5_HUMAN Spectrin beta chain, non-erythrocytic 5 OS=Homo sapiens GN=SPTBN5 PE=1 SV=2"	9031.ENSGALP00000014517	similar to beta chain spectrin	COG5069	KOG0517	_	PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:393-495;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:502-603;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:606-708;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:713-801;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:860-958;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:964-1066;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:1069-1174;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:1177-1279;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:1283-1385;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:1389-1489;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:1493-1595;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:1600-1702;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:1706-1807;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:1813-1914;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:1916-2019;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:2024-2125;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:2129-2234;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:2237-2343;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:2350-2449;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:2452-2554;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:2559-2662;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:2665-2767;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:2771-2872;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:2876-2977;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:2982-3085;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:3088-3191;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:3195-3297;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:3301-3403;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000100733|m.3119:3408-3487;PF00307.28|CH|Calponin homology (CH) domain|ENSGALT00000100733|m.3119:21-125;PF00307.28|CH|Calponin homology (CH) domain|ENSGALT00000100733|m.3119:147-248;PF00169.26|PH|PH domain|ENSGALT00000100733|m.3119:3683-3788;PF15410.3|PH_9|Pleckstrin homology domain|ENSGALT00000100733|m.3119:3700-3783;PF11971.5|CAMSAP_CH|CAMSAP CH domain|ENSGALT00000100733|m.3119:158-226
ENSGALG00000008952	0.551278497	1.505320484	-1.432834254	6.16E-05	0.000155763	down	yes	0.614945143	0.545800063	0.493090286	1.874832485	1.280045034	1.361083932	17	1265985	1279220	+	NOXA1	protein_coding	GO:0006801|superoxide metabolic process; GO:0010310|regulation of hydrogen peroxide metabolic process; GO:0060263|regulation of respiratory burst	GO:0005829|cytosol; GO:0043020|NADPH oxidase complex	GO:0016176|superoxide-generating NADPH oxidase activator activity; GO:0017124|SH3 domain binding; GO:0019899|enzyme binding; GO:0048365|Rac GTPase binding	ko:K21432|--	--	1533	XP_004945813.2	XP_004945813.2 NADPH oxidase activator 1 isoform X1 [Gallus gallus]	sp|Q86UR1|NOXA1_HUMAN	sp|Q86UR1|NOXA1_HUMAN NADPH oxidase activator 1 OS=Homo sapiens GN=NOXA1 PE=1 SV=1	9031.ENSGALP00000014542	NADPH oxidase activator 1	_	KOG4225	_	PF00564.21|PB1|PB1 domain|ENSGALT00000100492|m.11703:377-437
ENSGALG00000008969	1.132966368	0.541122721	1.052337441	0.006411345	0.011748299	up	yes	0.85260662	1.325279658	1.221012826	0.39767598	0.553012595	0.672679589	3	9260060	9446795	+	EPCAM	protein_coding	--	GO:0005887|integral component of plasma membrane; GO:0005923|bicellular tight junction; GO:0016328|lateral plasma membrane	GO:0098641|cadherin binding involved in cell-cell adhesion	"ko:K06737|EPCAM,TACSTD1,CD326"	--	1521	NP_001012582.1	NP_001012582.1 epithelial cell adhesion molecule precursor [Gallus gallus]	sp|Q5F381|EPCAM_CHICK	sp|Q5F381|EPCAM_CHICK Epithelial cell adhesion molecule OS=Gallus gallus GN=EPCAM PE=2 SV=1	9031.ENSGALP00000014571	tumor-associated calcium signal transducer 1 	_	_	NOG46689	PF00086.15|Thyroglobulin_1|Thyroglobulin type-1 repeat|ENSGALT00000062333|m.10785:119-165
ENSGALG00000008998	0.895427382	0.242141097	1.844367654	5.84E-09	2.35E-08	up	yes	0.960764844	0.795003655	0.930513645	0.247810255	0.320268001	0.158345033	3	9164062	9211550	-	TOGARAM2	protein_coding	--	--	--	--	--	3714	NP_001264726.1	NP_001264726.1 TOG array regulator of axonemal microtubules protein 2 [Gallus gallus]	sp|Q6ZUX3|TGRM2_HUMAN	sp|Q6ZUX3|TGRM2_HUMAN TOG array regulator of axonemal microtubules protein 2 OS=Homo sapiens GN=TOGARAM2 PE=2 SV=2	_	_	_	_	_	PF12348.5|CLASP_N|CLASP N terminal|ENSGALT00000105313|m.10777:485-660
ENSGALG00000009013	17.67102352	8.489363866	1.05677502	6.30E-31	1.04E-29	up	yes	16.95017976	18.67321334	17.38967745	7.492077485	9.034241045	8.941773067	3	13717148	13724622	+	MKKS	protein_coding	GO:0001947|heart looping; GO:0006457|protein folding; GO:0006458|'de novo' protein folding; GO:0007286|spermatid development; GO:0007368|determination of left/right symmetry; GO:0007507|heart development; GO:0007601|visual perception; GO:0007608|sensory perception of smell; GO:0008406|gonad development; GO:0010629|negative regulation of gene expression; GO:0014824|artery smooth muscle contraction; GO:0021756|striatum development; GO:0021766|hippocampus development; GO:0021987|cerebral cortex development; GO:0030837|negative regulation of actin filament polymerization; GO:0032402|melanosome transport; GO:0034260|negative regulation of GTPase activity; GO:0035176|social behavior; GO:0038108|negative regulation of appetite by leptin-mediated signaling pathway; GO:0040018|positive regulation of multicellular organism growth; GO:0042311|vasodilation; GO:0045444|fat cell differentiation; GO:0045494|photoreceptor cell maintenance; GO:0045776|negative regulation of blood pressure; GO:0046907|intracellular transport; GO:0048854|brain morphogenesis; GO:0050910|detection of mechanical stimulus involved in sensory perception of sound; GO:0051131|chaperone-mediated protein complex assembly; GO:0051216|cartilage development; GO:0051492|regulation of stress fiber assembly; GO:0051877|pigment granule aggregation in cell center; GO:0060027|convergent extension involved in gastrulation; GO:0060271|cilium assembly; GO:0060296|regulation of cilium beat frequency involved in ciliary motility; GO:0060324|face development; GO:0061077|chaperone-mediated protein folding; GO:1905515|non-motile cilium assembly	GO:0005622|intracellular; GO:0005813|centrosome; GO:0005829|cytosol; GO:0031514|motile cilium; GO:0036064|ciliary basal body; GO:1902636|kinociliary basal body	GO:0001103|RNA polymerase II repressing transcription factor binding; GO:0005524|ATP binding; GO:0044183|protein folding chaperone; GO:0051082|unfolded protein binding	ko:K09492|MKKS	--	3693	NP_001186339.1	NP_001186339.1 McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin [Gallus gallus]	sp|Q9NPJ1|MKKS_HUMAN	sp|Q9NPJ1|MKKS_HUMAN McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin OS=Homo sapiens GN=MKKS PE=1 SV=1	9031.ENSGALP00000014647	McKusick-Kaufman syndrome	COG0459	KOG0360	_	PF00118.21|Cpn60_TCP1|TCP-1/cpn60 chaperonin family|ENSGALT00000014663|m.10919:29-569
ENSGALG00000009020	6.162560438	15.2094938	-1.301979413	6.89E-49	2.41E-47	down	yes	6.53767827	6.211355902	5.738647143	15.27052783	15.31399459	15.04395896	3	13599642	13633726	+	JAG1	protein_coding	GO:0001525|angiogenesis; GO:0001709|cell fate determination; GO:0001974|blood vessel remodeling; GO:0002011|morphogenesis of an epithelial sheet; GO:0002456|T cell mediated immunity; GO:0003184|pulmonary valve morphogenesis; GO:0003215|cardiac right ventricle morphogenesis; GO:0007219|Notch signaling pathway; GO:0007220|Notch receptor processing; GO:0007399|nervous system development; GO:0030097|hemopoiesis; GO:0030216|keratinocyte differentiation; GO:0030334|regulation of cell migration; GO:0032495|response to muramyl dipeptide; GO:0035909|aorta morphogenesis; GO:0042127|regulation of cell population proliferation; GO:0042491|inner ear auditory receptor cell differentiation; GO:0045445|myoblast differentiation; GO:0045446|endothelial cell differentiation; GO:0045599|negative regulation of fat cell differentiation; GO:0045602|negative regulation of endothelial cell differentiation; GO:0045639|positive regulation of myeloid cell differentiation; GO:0045665|negative regulation of neuron differentiation; GO:0045669|positive regulation of osteoblast differentiation; GO:0045747|positive regulation of Notch signaling pathway; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0060411|cardiac septum morphogenesis; GO:0061073|ciliary body morphogenesis; GO:0061156|pulmonary artery morphogenesis; GO:0061309|cardiac neural crest cell development involved in outflow tract morphogenesis; GO:0061314|Notch signaling involved in heart development; GO:0061444|endocardial cushion cell development; GO:0072006|nephron development; GO:0072015|glomerular visceral epithelial cell development; GO:0072017|distal tubule development; GO:0072070|loop of Henle development; GO:0097150|neuronal stem cell population maintenance; GO:2000737|negative regulation of stem cell differentiation	GO:0005576|extracellular region; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0005912|adherens junction; GO:0016020|membrane; GO:0016324|apical plasma membrane	GO:0005112|Notch binding; GO:0005198|structural molecule activity; GO:0005509|calcium ion binding; GO:0005543|phospholipid binding; GO:0008083|growth factor activity	"ko:K06052|JAGGED,CD339"	ko01522|Endocrine resistance; ko04330|Notch signaling pathway; ko04371|Apelin signaling pathway; ko04658|Th1 and Th2 cell differentiation; ko05224|Breast cancer	3651	XP_415035.4	XP_415035.4 protein jagged-1 [Gallus gallus]	sp|P78504|JAG1_HUMAN	sp|P78504|JAG1_HUMAN Protein jagged-1 OS=Homo sapiens GN=JAG1 PE=1 SV=3	9031.ENSGALP00000038500	C-Serate-1 protein Fragment 	_	KOG1217	_	PF00008.24|EGF|EGF-like domain|ENSGALT00000014678|m.10916:297-328;PF00008.24|EGF|EGF-like domain|ENSGALT00000014678|m.10916:337-367;PF00008.24|EGF|EGF-like domain|ENSGALT00000014678|m.10916:375-405;PF00008.24|EGF|EGF-like domain|ENSGALT00000014678|m.10916:453-480;PF00008.24|EGF|EGF-like domain|ENSGALT00000014678|m.10916:488-517;PF00008.24|EGF|EGF-like domain|ENSGALT00000014678|m.10916:526-556;PF00008.24|EGF|EGF-like domain|ENSGALT00000014678|m.10916:630-659;PF00008.24|EGF|EGF-like domain|ENSGALT00000014678|m.10916:668-698;PF00008.24|EGF|EGF-like domain|ENSGALT00000014678|m.10916:706-735;PF00008.24|EGF|EGF-like domain|ENSGALT00000014678|m.10916:745-775;PF00008.24|EGF|EGF-like domain|ENSGALT00000014678|m.10916:783-812;PF00008.24|EGF|EGF-like domain|ENSGALT00000014678|m.10916:821-850;PF07657.10|MNNL|N terminus of Notch ligand|ENSGALT00000014678|m.10916:29-104;PF01414.16|DSL|Delta serrate ligand|ENSGALT00000014678|m.10916:164-226;PF12661.4|hEGF|Human growth factor-like EGF|ENSGALT00000014678|m.10916:318-330;PF12661.4|hEGF|Human growth factor-like EGF|ENSGALT00000014678|m.10916:470-481;PF12661.4|hEGF|Human growth factor-like EGF|ENSGALT00000014678|m.10916:507-519;PF12661.4|hEGF|Human growth factor-like EGF|ENSGALT00000014678|m.10916:725-737;PF12661.4|hEGF|Human growth factor-like EGF|ENSGALT00000014678|m.10916:764-776;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000014678|m.10916:409-442;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000014678|m.10916:484-515
ENSGALG00000009023	15.55825789	33.00818603	-1.084653349	3.51E-36	7.37E-35	down	yes	15.4235821	15.51097618	15.7402154	30.55299241	35.89934703	32.57221865	1	23568700	23587086	-	ING3	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated; GO:0040008|regulation of growth; GO:0043065|positive regulation of apoptotic process; GO:0043967|histone H4 acetylation; GO:0043968|histone H2A acetylation"	GO:0000812|Swr1 complex	GO:0046872|metal ion binding	ko:K11319|ING3	--	2142	NP_001025904.2	NP_001025904.2 inhibitor of growth protein 3 [Gallus gallus]	sp|Q5ZK36|ING3_CHICK	sp|Q5ZK36|ING3_CHICK Inhibitor of growth protein 3 OS=Gallus gallus GN=ING3 PE=2 SV=1	_	_	_	_	_	PF12998.4|ING|Inhibitor of growth proteins N-terminal histone-binding|ENSGALT00000014681|m.655:3-104
ENSGALG00000009032	1.563255293	0.417963306	1.878193787	1.82E-09	7.70E-09	up	yes	1.688816958	1.714489007	1.286459912	0.439785304	0.359649734	0.45445488	8	19953424	19965159	-	PIF1	protein_coding	GO:0000723|telomere maintenance; GO:0006281|DNA repair; GO:0006310|DNA recombination	GO:0005634|nucleus; GO:0005739|mitochondrion	GO:0003677|DNA binding; GO:0003678|DNA helicase activity; GO:0005524|ATP binding	ko:K15255|PIF1	--	1854	XP_426648.4	XP_426648.4 ATP-dependent DNA helicase PIF1 isoform X2 [Gallus gallus]	sp|Q0R4F1|PIF1_XENLA	sp|Q0R4F1|PIF1_XENLA ATP-dependent DNA helicase PIF1 OS=Xenopus laevis GN=pif1 PE=2 SV=1	9031.ENSGALP00000014682	PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)	COG0507	KOG0987	_	PF05970.11|PIF1|PIF1-like helicase|ENSGALT00000014698|m.7663:186-483;PF13604.3|AAA_30|AAA domain|ENSGALT00000014698|m.7663:186-382
ENSGALG00000009037	0.302288198	0.994603006	-1.685675543	0.000239806	0.000555197	down	yes	0.400692693	0.065286273	0.440885628	0.937812278	1.258975936	0.787020802	3	12892857	12984138	-	SPTLC3	protein_coding	GO:0030148|sphingolipid biosynthetic process; GO:0046520|sphingoid biosynthetic process	GO:0005789|endoplasmic reticulum membrane; GO:0016021|integral component of membrane; GO:0017059|serine C-palmitoyltransferase complex	GO:0004758|serine C-palmitoyltransferase activity; GO:0030170|pyridoxal phosphate binding	ko:K00654|SPT	ko00600|Sphingolipid metabolism; ko01100|Metabolic pathways; ko04071|Sphingolipid signaling pathway; ko04138|Autophagy - yeast	2367	XP_001231526.2	XP_001231526.2 serine palmitoyltransferase 3 [Gallus gallus]	sp|Q9NUV7|SPTC3_HUMAN	sp|Q9NUV7|SPTC3_HUMAN Serine palmitoyltransferase 3 OS=Homo sapiens GN=SPTLC3 PE=1 SV=3	9031.ENSGALP00000014693	"serine palmitoyltransferase, long chain base subunit 3"	COG0156	KOG1357	_	PF00155.18|Aminotran_1_2|Aminotransferase class I and II|ENSGALT00000014709|m.10912:162-522
ENSGALG00000009042	0.866511572	4.288472434	-2.293979012	3.85E-19	3.43E-18	down	yes	0.538634104	0.998932982	1.06196763	4.159386974	4.66154993	4.044480399	3	12825298	12864186	-	ISM1	protein_coding	--	GO:0005576|extracellular region	--	--	--	1663	XP_021247874.1	XP_021247874.1 isthmin-1 isoform X1 [Numida meleagris]	sp|B1AKI9|ISM1_HUMAN	sp|B1AKI9|ISM1_HUMAN Isthmin-1 OS=Homo sapiens GN=ISM1 PE=2 SV=2	9031.ENSGALP00000014704	chromosome 20 open reading frame 82	_	_	NOG41256	PF03782.14|AMOP|AMOP domain|ENSGALT00000014720|m.10911:296-457;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000014720|m.10911:223-263
ENSGALG00000009057	3.860620958	9.211213706	-1.252391618	2.72E-29	4.09E-28	down	yes	3.837596259	3.991568919	3.752697696	9.446564495	8.993582533	9.193494089	3	12725381	12798093	+	TASP1	protein_coding	"GO:0006508|proteolysis; GO:0045893|positive regulation of transcription, DNA-templated"	--	GO:0004298|threonine-type endopeptidase activity; GO:0042802|identical protein binding	ko:K08657|TASP1	--	2937	NP_001012808.1	NP_001012808.1 threonine aspartase 1 [Gallus gallus]	sp|Q9H6P5|TASP1_HUMAN	sp|Q9H6P5|TASP1_HUMAN Threonine aspartase 1 OS=Homo sapiens GN=TASP1 PE=1 SV=1	9031.ENSGALP00000014727	taspase 1 	COG1446	KOG1592	_	PF01112.15|Asparaginase_2|Asparaginase|ENSGALT00000014743|m.10909:44-351
ENSGALG00000009063	1.969923019	4.949535597	-1.324760697	1.81E-18	1.55E-17	down	yes	1.654788557	1.94607297	2.30890753	4.954914426	5.02186822	4.871824145	4	17406321	17430410	-	ENSGALG00000009063	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006974|cellular response to DNA damage stimulus; GO:0007417|central nervous system development; GO:0007623|circadian rhythm; GO:0019216|regulation of lipid metabolic process; GO:0032922|circadian regulation of gene expression; GO:0045739|positive regulation of DNA repair; GO:0045893|positive regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0051775|response to redox state; GO:0060548|negative regulation of cell death; GO:2001020|regulation of response to DNA damage stimulus"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005667|transcription factor complex; GO:0005829|cytosol	GO:0001047|core promoter binding; GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity; GO:0046872|metal ion binding; GO:0046983|protein dimerization activity; GO:0051879|Hsp90 protein binding	ko:K09026|NPAS2	ko04710|Circadian rhythm	3216	XP_015134129.1	XP_015134129.1 circadian clock protein PASD1 isoform X2 [Gallus gallus]	sp|Q99743|NPAS2_HUMAN	sp|Q99743|NPAS2_HUMAN Neuronal PAS domain-containing protein 2 OS=Homo sapiens GN=NPAS2 PE=1 SV=3	_	_	_	_	_	PF14598.3|PAS_11|PAS domain|ENSGALT00000014751|m.16668:251-355;PF08447.9|PAS_3|PAS fold|ENSGALT00000014751|m.16668:264-350;PF00989.22|PAS|PAS fold|ENSGALT00000014751|m.16668:87-155;PF00010.23|HLH|Helix-loop-helix DNA-binding domain|ENSGALT00000014751|m.16668:10-60
ENSGALG00000009065	28.70002464	12.21094431	1.232198803	1.13E-48	3.92E-47	up	yes	26.6247679	30.66084967	28.81445635	11.540873	13.35575367	11.73620625	4	17503248	17509318	-	VMA21	protein_coding	GO:0070072|vacuolar proton-transporting V-type ATPase complex assembly	GO:0005789|endoplasmic reticulum membrane; GO:0012507|ER to Golgi transport vesicle membrane; GO:0016021|integral component of membrane; GO:0033116|endoplasmic reticulum-Golgi intermediate compartment membrane	--	--	--	3208	XP_015716316.1	XP_015716316.1 PREDICTED: vacuolar ATPase assembly integral membrane protein VMA21 [Coturnix japonica]	sp|Q5ZLL0|VMA21_CHICK	sp|Q5ZLL0|VMA21_CHICK Vacuolar ATPase assembly integral membrane protein VMA21 OS=Gallus gallus GN=VMA21 PE=3 SV=1	9031.ENSGALP00000014737	Vacuolar ATPase assembly integral membrane protein VMA21 homolog ; Required for the assembly [...] 	_	KOG4783	_	PF09446.7|VMA21|VMA21-like domain|ENSGALT00000014753|m.16669:27-89
ENSGALG00000009104	1.845046178	4.93633746	-1.414905569	3.36E-30	5.33E-29	down	yes	2.00303407	1.730102816	1.802001648	4.473675698	5.9003073	4.43502938	1	24435899	24484038	+	ANKRD26	protein_coding	GO:0045599|negative regulation of fat cell differentiation	GO:0005813|centrosome	--	--	--	8865	NP_001274116.1	NP_001274116.1 ankyrin repeat domain-containing protein 26 [Gallus gallus]	sp|Q9UPS8|ANR26_HUMAN	sp|Q9UPS8|ANR26_HUMAN Ankyrin repeat domain-containing protein 26 OS=Homo sapiens GN=ANKRD26 PE=1 SV=3	_	_	_	_	_	PF14915.3|CCDC144C|CCDC144C protein coiled-coil region|ENSGALT00000014827|m.658:1578-1882;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000014827|m.658:39-130;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000014827|m.658:123-196;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000014827|m.658:101-141;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000014827|m.658:137-186;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000014827|m.658:168-219;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000014827|m.658:199-244;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000014827|m.658:68-98;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000014827|m.658:132-164;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000014827|m.658:166-196;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000014827|m.658:200-229;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000014827|m.658:119-173;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000014827|m.658:185-239;PF12001.5|DUF3496|Domain of unknown function (DUF3496)|ENSGALT00000014827|m.658:2294-2408;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000014827|m.658:67-94;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000014827|m.658:199-226
ENSGALG00000009110	21.35608267	8.662821143	1.300749161	3.29E-15	2.22E-14	up	yes	22.72303218	20.52386216	20.82135368	10.52919315	8.075164097	7.384106176	1	24490276	24495990	-	LSM8	protein_coding	"GO:0000398|mRNA splicing, via spliceosome"	GO:0005688|U6 snRNP; GO:0046540|U4/U6 x U5 tri-snRNP complex; GO:0071011|precatalytic spliceosome	GO:0003723|RNA binding	ko:K12627|LSM8	ko03018|RNA degradation; ko03040|Spliceosome	640	NP_001264284.1	"NP_001264284.1 LSM8 homolog, U6 small nuclear RNA associated [Gallus gallus]"	sp|Q3ZCE0|LSM8_BOVIN	sp|Q3ZCE0|LSM8_BOVIN U6 snRNA-associated Sm-like protein LSm8 OS=Bos taurus GN=LSM8 PE=3 SV=3	9031.ENSGALP00000014820	"LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae)"	_	KOG1784	_	PF01423.19|LSM|LSM domain|ENSGALT00000014836|m.662:64-130
ENSGALG00000009128	14.03447487	6.282410551	1.158317974	1.14E-12	6.32E-12	up	yes	12.84127205	14.42986616	14.83228642	5.775264496	6.293142198	6.77882496	4	18042924	18045047	-	ENSGALG00000009128	protein_coding	--	--	--	--	--	755	XP_001234388.2	XP_001234388.2 uncharacterized protein CXorf40 homolog [Gallus gallus]	sp|Q8TE69|CX04A_HUMAN	sp|Q8TE69|CX04A_HUMAN Protein CXorf40A OS=Homo sapiens GN=CXorf40A PE=1 SV=2	9031.ENSGALP00000014845	hypothetical protein LOC772269	_	_	NOG45203	_
ENSGALG00000009129	0.270190713	5.827598137	-4.380893857	3.68E-34	7.13E-33	down	yes	0.073131283	0.375339439	0.362101416	5.529148089	7.245250319	4.708396001	2	24451494	24453892	-	DLX5	protein_coding	GO:0001649|osteoblast differentiation; GO:0001958|endochondral ossification; GO:0008283|cell population proliferation; GO:0021889|olfactory bulb interneuron differentiation; GO:0030326|embryonic limb morphogenesis; GO:0030509|BMP signaling pathway; GO:0030855|epithelial cell differentiation; GO:0042472|inner ear morphogenesis; GO:0048646|anatomical structure formation involved in morphogenesis; GO:0050679|positive regulation of epithelial cell proliferation; GO:0060021|roof of mouth development; GO:0060166|olfactory pit development; GO:0060325|face morphogenesis; GO:0090263|positive regulation of canonical Wnt signaling pathway; GO:0097376|interneuron axon guidance; GO:1901522|positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus	GO:0000790|nuclear chromatin; GO:0005737|cytoplasm	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0071837|HMG box domain binding"	ko:K18489|DLX5	ko04550|Signaling pathways regulating pluripotency of stem cells	1441	NP_989490.1	NP_989490.1 homeobox protein DLX-5 [Gallus gallus]	sp|P50577|DLX5_CHICK	sp|P50577|DLX5_CHICK Homeobox protein DLX-5 OS=Gallus gallus GN=DLX5 PE=2 SV=1	9031.ENSGALP00000015233	"Homeobox protein DLX-5 (cDlx); Could be involved in apical ectodermal ridge activity, patter [...] "	_	KOG0850	_	PF12413.5|DLL_N|Homeobox protein distal-less-like N terminal|ENSGALT00000014862|m.67:32-116;PF00046.26|Homeobox|Homeobox domain|ENSGALT00000014862|m.67:137-193
ENSGALG00000009130	11.07654792	48.09051597	-2.117242155	1.92E-146	7.04E-144	down	yes	10.73480706	11.32252917	11.17230753	45.10747821	49.27938361	49.88468611	3	16861604	16894451	-	GPCPD1	protein_coding	GO:0007519|skeletal muscle tissue development; GO:0030643|cellular phosphate ion homeostasis; GO:0046475|glycerophospholipid catabolic process	GO:0005829|cytosol	GO:0008889|glycerophosphodiester phosphodiesterase activity; GO:0047389|glycerophosphocholine phosphodiesterase activity; GO:2001070|starch binding	ko:K18695|GPCPD1	ko00564|Glycerophospholipid metabolism; ko05231|Choline metabolism in cancer	2037	XP_419376.3	XP_419376.3 glycerophosphocholine phosphodiesterase GPCPD1 isoform X1 [Gallus gallus]	sp|Q9NPB8|GPCP1_HUMAN	sp|Q9NPB8|GPCP1_HUMAN Glycerophosphocholine phosphodiesterase GPCPD1 OS=Homo sapiens GN=GPCPD1 PE=1 SV=2	9031.ENSGALP00000014847	glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)	COG0584	KOG2421	_	PF03009.14|GDPD|Glycerophosphoryl diester phosphodiesterase family|ENSGALT00000014863|m.11049:324-612;PF00686.16|CBM_20|Starch binding domain|ENSGALT00000014863|m.11049:5-88
ENSGALG00000009205	4.607259625	11.74231543	-1.347836262	5.94E-32	1.04E-30	down	yes	4.07883901	4.474439535	5.26850033	11.63046237	10.19883927	13.39764466	14	14438034	14559559	-	ENSGALG00000009205	protein_coding	--	--	--	--	--	4254	XP_019476119.1	XP_019476119.1 PREDICTED: ankyrin repeat and fibronectin type-III domain-containing protein 1-like isoform X1 [Meleagris gallopavo]	sp|Q8N957|ANKF1_HUMAN	sp|Q8N957|ANKF1_HUMAN Ankyrin repeat and fibronectin type-III domain-containing protein 1 OS=Homo sapiens GN=ANKFN1 PE=2 SV=2	9031.ENSGALP00000014972	similar to ankyrin-repeat and fibronectin type III domain containing 1	_	KOG4485	_	PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000105903|m.10081:508-594
ENSGALG00000009224	2.131403985	0.996135451	1.089732451	8.84E-05	0.000218939	up	yes	1.986713196	2.279989316	2.127509442	1.061380576	1.241237986	0.68578779	7	15680124	15682118	+	TTC30B	protein_coding	GO:0035735|intraciliary transport involved in cilium assembly; GO:0042073|intraciliary transport; GO:0060271|cilium assembly	GO:0005929|cilium; GO:0030992|intraciliary transport particle B; GO:0097542|ciliary tip	--	"ko:K19683|TTC30,DYF1"	--	1830	NP_001269324.1	NP_001269324.1 tetratricopeptide repeat protein 30A [Gallus gallus]	sp|Q8N4P2|TT30B_HUMAN	sp|Q8N4P2|TT30B_HUMAN Tetratricopeptide repeat protein 30B OS=Homo sapiens GN=TTC30B PE=1 SV=2	9031.ENSGALP00000014995	tetratricopeptide repeat domain 30A	_	KOG4340	_	PF07719.14|TPR_2|Tetratricopeptide repeat|ENSGALT00000015011|m.6050:45-74;PF13432.3|TPR_16|Tetratricopeptide repeat|ENSGALT00000015011|m.6050:51-98;PF13432.3|TPR_16|Tetratricopeptide repeat|ENSGALT00000015011|m.6050:81-141;PF13181.3|TPR_8|Tetratricopeptide repeat|ENSGALT00000015011|m.6050:47-71
ENSGALG00000009254	0.759983269	1.934073159	-1.336183508	2.45E-07	8.37E-07	down	yes	0.634042151	0.929760512	0.716147145	1.809263359	2.032031656	1.960924462	6	29917122	29935121	+	ENO4	protein_coding	GO:0006096|glycolytic process	GO:0000015|phosphopyruvate hydratase complex	GO:0000287|magnesium ion binding; GO:0004634|phosphopyruvate hydratase activity	--	--	2410	XP_421780.4	XP_421780.4 enolase 4 isoform X1 [Gallus gallus]	sp|A6NNW6|ENO4_HUMAN	sp|A6NNW6|ENO4_HUMAN Enolase 4 OS=Homo sapiens GN=ENO4 PE=2 SV=2	9031.ENSGALP00000015047	enolase family member 4	COG0148	KOG2670	_	"PF00113.19|Enolase_C|Enolase, C-terminal TIM barrel domain|ENSGALT00000107236|m.5351:358-563;PF03952.13|Enolase_N|Enolase, N-terminal domain|ENSGALT00000107236|m.5351:59-153"
ENSGALG00000009270	0.969699984	0.362086174	1.396703235	0.006193519	0.011387141	up	yes	1.074414731	1.050349085	0.784336137	0.303104366	0.566569466	0.21658469	7	16302455	16304988	-	HOXD10	protein_coding	GO:0007338|single fertilization; GO:0007519|skeletal muscle tissue development; GO:0008344|adult locomotory behavior; GO:0009952|anterior/posterior pattern specification; GO:0009954|proximal/distal pattern formation; GO:0021520|spinal cord motor neuron cell fate specification; GO:0030326|embryonic limb morphogenesis; GO:0035136|forelimb morphogenesis; GO:0035137|hindlimb morphogenesis; GO:0048704|embryonic skeletal system morphogenesis; GO:0048935|peripheral nervous system neuron development; GO:0050905|neuromuscular process	GO:0005654|nucleoplasm; GO:0005829|cytosol; GO:0036464|cytoplasmic ribonucleoprotein granule	"GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003682|chromatin binding"	ko:K09295|HOXD10	ko05205|Proteoglycans in cancer; ko05206|MicroRNAs in cancer	1177	XP_001234539.2	XP_001234539.2 homeobox protein Hox-D10 [Gallus gallus]	sp|P28358|HXD10_HUMAN	sp|P28358|HXD10_HUMAN Homeobox protein Hox-D10 OS=Homo sapiens GN=HOXD10 PE=1 SV=2	9615.ENSCAFP00000019805	homeobox D10	_	KOG0487	_	PF00046.26|Homeobox|Homeobox domain|ENSGALT00000038688|m.6078:318-374
ENSGALG00000009279	0.798653866	1.98535386	-1.303050407	1.60E-07	5.59E-07	down	yes	0.81063214	0.761995114	0.823334344	1.720049189	1.915391726	2.320620665	1	4524285	4616058	-	SFMBT2	protein_coding	"GO:0006355|regulation of transcription, DNA-templated; GO:0010629|negative regulation of gene expression"	GO:0005634|nucleus; GO:0016235|aggresome; GO:0016607|nuclear speck; GO:0043231|intracellular membrane-bounded organelle	GO:0042393|histone binding	--	--	2535	XP_025009086.1	XP_025009086.1 scm-like with four MBT domains protein 2 [Gallus gallus]	sp|Q5VUG0|SMBT2_HUMAN	sp|Q5VUG0|SMBT2_HUMAN Scm-like with four MBT domains protein 2 OS=Homo sapiens GN=SFMBT2 PE=1 SV=1	59729.ENSTGUP00000002135	Scm-like with four MBT domains protein 2 [Taeniopygia guttata]	_	KOG3766	_	PF02820.15|MBT|mbt repeat|ENSGALT00000015096|m.283:50-119;PF02820.15|MBT|mbt repeat|ENSGALT00000015096|m.283:164-231;PF02820.15|MBT|mbt repeat|ENSGALT00000015096|m.283:276-347;PF02820.15|MBT|mbt repeat|ENSGALT00000015096|m.283:384-452;PF12140.5|DUF3588|Protein of unknown function (DUF3588)|ENSGALT00000015096|m.283:490-602;PF00536.27|SAM_1|SAM domain (Sterile alpha motif)|ENSGALT00000015096|m.283:773-835;PF02198.13|SAM_PNT|Sterile alpha motif (SAM)/Pointed domain|ENSGALT00000015096|m.283:760-818;PF07647.14|SAM_2|SAM domain (Sterile alpha motif)|ENSGALT00000015096|m.283:773-835
ENSGALG00000009282	11.75630057	33.70190034	-1.518597159	2.42E-99	2.96E-97	down	yes	11.83123317	11.4790271	11.95864144	32.04321149	34.9162724	34.14621713	5	26349055	26370948	+	ELMSAN1	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006357|regulation of transcription by RNA polymerase II"	GO:0000118|histone deacetylase complex; GO:0005654|nucleoplasm; GO:0005667|transcription factor complex	GO:0003700|DNA-binding transcription factor activity; GO:0008134|transcription factor binding; GO:0044212|transcription regulatory region DNA binding	--	--	3692	XP_004941715.1	XP_004941715.1 ELM2 and SANT domain-containing protein 1 isoform X1 [Gallus gallus]	sp|Q6PJG2|EMSA1_HUMAN	sp|Q6PJG2|EMSA1_HUMAN ELM2 and SANT domain-containing protein 1 OS=Homo sapiens GN=ELMSAN1 PE=1 SV=2	9031.ENSGALP00000015086	chromosome 14 open reading frame 43	_	KOG4167	_	PF01448.21|ELM2|ELM2 domain|ENSGALT00000015102|m.3151:733-788
ENSGALG00000009330	29.1061826	8.365979136	1.797491464	2.56E-127	6.87E-125	up	yes	27.60769344	29.75135654	29.95949782	8.147232641	8.835976062	8.114728706	3	17705163	17711133	-	DEGS1	protein_coding	GO:0006633|fatty acid biosynthetic process; GO:0046513|ceramide biosynthetic process	GO:0005739|mitochondrion; GO:0005789|endoplasmic reticulum membrane; GO:0016021|integral component of membrane	GO:0042284|sphingolipid delta-4 desaturase activity	ko:K04712|DEGS	ko00600|Sphingolipid metabolism; ko01100|Metabolic pathways; ko04071|Sphingolipid signaling pathway	3632	NP_001012583.1	NP_001012583.1 sphingolipid delta(4)-desaturase DES1 [Gallus gallus]	sp|Q5F3C1|DEGS1_CHICK	sp|Q5F3C1|DEGS1_CHICK Sphingolipid delta(4)-desaturase DES1 OS=Gallus gallus GN=DEGS1 PE=2 SV=1	9031.ENSGALP00000015178	Sphingolipid delta(4)-desaturase DES1 (EC 1.14.-.-)(Degenerative spermatocyte homolog 1); Ha [...] 	_	KOG2987	_	PF00487.21|FA_desaturase|Fatty acid desaturase|ENSGALT00000015194|m.11094:80-298;PF08557.7|Lipid_DES|Sphingolipid Delta4-desaturase (DES)|ENSGALT00000015194|m.11094:20-54
ENSGALG00000009349	1.047492851	0.142083944	2.797708155	9.59E-12	4.93E-11	up	yes	1.092043297	0.750644151	1.299791103	0.171154212	0.161962175	0.093135445	9	19920957	19930995	+	SLC7A14	protein_coding	GO:0010923|negative regulation of phosphatase activity	GO:0005765|lysosomal membrane; GO:0016021|integral component of membrane	GO:0015171|amino acid transmembrane transporter activity	ko:K13871|SLC7A14	--	2316	XP_422796.3	XP_422796.3 probable cationic amino acid transporter [Gallus gallus]	sp|Q8TBB6|S7A14_HUMAN	sp|Q8TBB6|S7A14_HUMAN Probable cationic amino acid transporter OS=Homo sapiens GN=SLC7A14 PE=2 SV=3	_	_	_	_	_	PF13520.3|AA_permease_2|Amino acid permease|ENSGALT00000015226|m.9253:53-433;PF00324.18|AA_permease|Amino acid permease|ENSGALT00000015226|m.9253:58-430;PF13906.3|AA_permease_C|C-terminus of AA_permease|ENSGALT00000015226|m.9253:627-677
ENSGALG00000009352	2.25741642	5.653609308	-1.320672375	2.16E-23	2.47E-22	down	yes	2.262995121	2.051615459	2.457638681	5.797508695	5.666357448	5.496961782	5	26716366	26875132	+	DPF3	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated; GO:0007399|nervous system development; GO:0016569|covalent chromatin modification"	GO:0005634|nucleus	GO:0003676|nucleic acid binding; GO:0046872|metal ion binding	--	--	2302	XP_021257263.1	XP_021257263.1 zinc finger protein DPF3 isoform X3 [Numida meleagris]	sp|P58270|DPF3_CHICK	sp|P58270|DPF3_CHICK Zinc finger protein DPF3 OS=Gallus gallus GN=DPF3 PE=2 SV=1	_	_	_	_	_	PF14051.3|Requiem_N|N-terminal domain of DPF2/REQ.|ENSGALT00000015230|m.3173:23-93
ENSGALG00000009356	16.76387938	36.26104839	-1.112602059	5.25E-55	2.19E-53	down	yes	17.1095124	16.66726505	16.5148607	34.55951443	37.5854742	36.63815655	9	19949891	19961418	-	SKIL	protein_coding	GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0030512|negative regulation of transforming growth factor beta receptor signaling pathway	--	GO:0046332|SMAD binding	ko:K18499|SKIL	ko04550|Signaling pathways regulating pluripotency of stem cells	3055	NP_990505.1	NP_990505.1 ski-like protein [Gallus gallus]	sp|Q5R431|SKIL_PONAB	sp|Q5R431|SKIL_PONAB Ski-like protein OS=Pongo abelii GN=SKIL PE=2 SV=1	9031.ENSGALP00000015220	SKI-like 	_	_	NOG82850	PF02437.14|Ski_Sno|SKI/SNO/DAC family|ENSGALT00000079331|m.9257:133-237;PF08782.7|c-SKI_SMAD_bind|c-SKI Smad4 binding domain|ENSGALT00000079331|m.9257:264-358
ENSGALG00000009360	7.288283881	2.559263344	1.506202498	2.99E-21	3.02E-20	up	yes	7.82812879	6.696189299	7.340533555	2.557097453	3.05073322	2.069959358	3	17779866	17799623	-	CAPN2	protein_coding	GO:0006508|proteolysis; GO:0051493|regulation of cytoskeleton organization; GO:0071230|cellular response to amino acid stimulus	GO:0005737|cytoplasm; GO:0005886|plasma membrane; GO:0030425|dendrite	GO:0004198|calcium-dependent cysteine-type endopeptidase activity; GO:0005509|calcium ion binding; GO:1990782|protein tyrosine kinase binding	ko:K03853|CAPN2	ko04141|Protein processing in endoplasmic reticulum; ko04210|Apoptosis; ko04510|Focal adhesion; ko05010|Alzheimer's disease	2302	ACI95286.1	ACI95286.1 CAPN2 [Gallus gallus]	sp|Q92178|CAN2_CHICK	sp|Q92178|CAN2_CHICK Calpain-2 catalytic subunit OS=Gallus gallus GN=CAPN2 PE=2 SV=3	9031.ENSGALP00000015225	Calpain-2 catalytic subunit Precursor (EC 3.4.22.53)(Calpain-2 large subunit)(Calcium-activa [...] 	_	KOG0045	_	"PF00648.18|Peptidase_C2|Calpain family cysteine protease|ENSGALT00000015245|m.11098:46-342;PF01067.19|Calpain_III|Calpain large subunit, domain III|ENSGALT00000015245|m.11098:363-506;PF13833.3|EF-hand_8|EF-hand domain pair|ENSGALT00000015245|m.11098:545-603"
ENSGALG00000009365	310.8768225	118.3707193	1.392955339	2.54E-89	2.47E-87	up	yes	314.1546461	311.8759042	306.5999172	110.0754384	132.3255228	112.7111967	2	22493952	22507735	-	CYP51A1	protein_coding	"GO:0033488|cholesterol biosynthetic process via 24,25-dihydrolanosterol"	GO:0005783|endoplasmic reticulum; GO:0005789|endoplasmic reticulum membrane; GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0031090|organelle membrane	GO:0005506|iron ion binding; GO:0008398|sterol 14-demethylase activity; GO:0020037|heme binding	ko:K05917|CYP51	ko00100|Steroid biosynthesis; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko01130|Biosynthesis of antibiotics	2525	XP_015136878.1	XP_015136878.1 lanosterol 14-alpha demethylase isoform X2 [Gallus gallus]	sp|O46420|CP51A_PIG	sp|O46420|CP51A_PIG Lanosterol 14-alpha demethylase OS=Sus scrofa GN=CYP51A1 PE=2 SV=1	_	_	_	_	_	PF00067.19|p450|Cytochrome P450|ENSGALT00000015253|m.15120:93-523
ENSGALG00000009368	0.805211189	1.822555638	-1.168611242	5.04E-07	1.66E-06	down	yes	0.862656993	0.619850839	0.933125736	1.771698282	1.808241744	1.887726888	5	26908701	27134788	-	RGS6	protein_coding	GO:0007186|G protein-coupled receptor signaling pathway; GO:0008277|regulation of G protein-coupled receptor signaling pathway; GO:0009968|negative regulation of signal transduction; GO:0035556|intracellular signal transduction; GO:0043547|positive regulation of GTPase activity	GO:0005634|nucleus; GO:0005829|cytosol; GO:0005834|heterotrimeric G-protein complex; GO:0005886|plasma membrane; GO:0019898|extrinsic component of membrane	GO:0005096|GTPase activator activity	ko:K16449|RGS	--	3054	NP_001186381.1	NP_001186381.1 regulator of G-protein signaling 6 [Gallus gallus]	sp|P49758|RGS6_HUMAN	sp|P49758|RGS6_HUMAN Regulator of G-protein signaling 6 OS=Homo sapiens GN=RGS6 PE=1 SV=5	9031.ENSGALP00000015245	Regulator of G-protein signalling 6 Fragment 	_	KOG3589	_	"PF00615.16|RGS|Regulator of G protein signaling domain|ENSGALT00000044464|m.3174:336-450;PF00610.18|DEP|Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)|ENSGALT00000044464|m.3174:43-113;PF00631.19|G-gamma|GGL domain|ENSGALT00000044464|m.3174:256-317"
ENSGALG00000009388	1.276866091	4.283938041	-1.738439437	1.71E-17	1.37E-16	down	yes	1.341133937	1.153510666	1.335953671	4.520783402	4.549316391	3.781714331	3	17861903	17932443	+	SUSD4	protein_coding	"GO:0030449|regulation of complement activation; GO:0045957|negative regulation of complement activation, alternative pathway; GO:0045959|negative regulation of complement activation, classical pathway"	GO:0016021|integral component of membrane	--	--	--	1714	XP_015139422.1	XP_015139422.1 sushi domain-containing protein 4 [Gallus gallus]	sp|Q8BH32|SUSD4_MOUSE	sp|Q8BH32|SUSD4_MOUSE Sushi domain-containing protein 4 OS=Mus musculus GN=Susd4 PE=2 SV=1	_	_	_	_	_	PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000015298|m.11102:9-69;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000015298|m.11102:81-131;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000015298|m.11102:134-191;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000015298|m.11102:197-251
ENSGALG00000009392	0.371235695	0.868500444	-1.204359809	0.000980289	0.002067522	down	yes	0.305632767	0.373483684	0.434590634	0.812406696	1.087889782	0.705204853	3	17958137	17960722	+	TLR5	protein_coding	GO:0002755|MyD88-dependent toll-like receptor signaling pathway; GO:0006954|inflammatory response; GO:0008584|male gonad development; GO:0032757|positive regulation of interleukin-8 production; GO:0034123|positive regulation of toll-like receptor signaling pathway; GO:0034146|toll-like receptor 5 signaling pathway; GO:0042742|defense response to bacterium; GO:0045087|innate immune response; GO:0045429|positive regulation of nitric oxide biosynthetic process; GO:0050707|regulation of cytokine secretion; GO:0071222|cellular response to lipopolysaccharide; GO:0071260|cellular response to mechanical stimulus	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0004888|transmembrane signaling receptor activity; GO:0005149|interleukin-1 receptor binding	ko:K10168|TLR5	ko04620|Toll-like receptor signaling pathway; ko05130|Pathogenic Escherichia coli infection; ko05132|Salmonella infection; ko05134|Legionellosis; ko05321|Inflammatory bowel disease (IBD)	2586	XP_015139227.1	XP_015139227.1 toll-like receptor 5 isoform X1 [Gallus gallus]	sp|O60602|TLR5_HUMAN	sp|O60602|TLR5_HUMAN Toll-like receptor 5 OS=Homo sapiens GN=TLR5 PE=1 SV=4	9031.ENSGALP00000015286	toll-like receptor 5 	_	KOG4641	_	PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000015302|m.11104:88-133;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000015302|m.11104:292-350;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000015302|m.11104:314-374;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000015302|m.11104:339-398;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000015302|m.11104:364-416;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000015302|m.11104:504-562;PF01582.17|TIR|TIR domain|ENSGALT00000015302|m.11104:697-844;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000015302|m.11104:88-188;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000015302|m.11104:307-396;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000015302|m.11104:500-558
ENSGALG00000009421	18.6203111	7.916972411	1.232809905	7.59E-38	1.74E-36	up	yes	19.62106645	18.34810606	17.8917608	8.392188699	7.636582979	7.722145556	5	28087093	28091730	-	SRSF5	protein_coding	"GO:0000398|mRNA splicing, via spliceosome; GO:0006369|termination of RNA polymerase II transcription; GO:0006376|mRNA splice site selection; GO:0006397|mRNA processing; GO:0006405|RNA export from nucleus; GO:0006406|mRNA export from nucleus; GO:0031124|mRNA 3'-end processing; GO:0032869|cellular response to insulin stimulus; GO:0033120|positive regulation of RNA splicing; GO:0051726|regulation of cell cycle; GO:0097421|liver regeneration"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005730|nucleolus; GO:0005829|cytosol; GO:0016607|nuclear speck	GO:0003723|RNA binding; GO:0043422|protein kinase B binding	ko:K12893|SFRS4_5_6	ko03040|Spliceosome; ko05168|Herpes simplex infection	1655	OPJ83050.1	OPJ83050.1 serine/arginine-rich splicing factor 5 isoform B [Patagioenas fasciata monilis]	sp|Q13243|SRSF5_HUMAN	sp|Q13243|SRSF5_HUMAN Serine/arginine-rich splicing factor 5 OS=Homo sapiens GN=SRSF5 PE=1 SV=1	59729.ENSTGUP00000011783	"Splicing factor, arginine/serine-rich 5 (Pre-mRNA-splicing factor SRP40)(Delayed-early prote [...] "	COG0724	KOG0106	_	"PF00076.19|RRM_1|RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)|ENSGALT00000015342|m.3206:65-126;PF00076.19|RRM_1|RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)|ENSGALT00000015342|m.3206:168-233"
ENSGALG00000009424	14.8791611	45.087318	-1.598779167	2.87E-109	4.44E-107	down	yes	14.35694484	14.65906023	15.62147823	43.37535541	46.82633091	45.06026768	1	26049718	26110344	-	FOXP2	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0021757|caudate nucleus development; GO:0021758|putamen development"	GO:0005634|nucleus	GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity; GO:0042803|protein homodimerization activity; GO:0043565|sequence-specific DNA binding; GO:0046872|metal ion binding	ko:K09409|FOXP	--	2870	AAR28756.1	AAR28756.1 forkhead box P2 [Taeniopygia guttata]	sp|Q8MJ99|FOXP2_GORGO	sp|Q8MJ99|FOXP2_GORGO Forkhead box protein P2 OS=Gorilla gorilla gorilla GN=FOXP2 PE=2 SV=1	9031.ENSGALP00000012590	FoxP2 Fragment 	COG5025	KOG4385	_	PF16159.2|FOXP-CC|FOXP coiled-coil domain|ENSGALT00000015345|m.684:140-208;PF00250.15|Forkhead|Forkhead domain|ENSGALT00000015345|m.684:302-377
ENSGALG00000009433	33.0547796	76.95092193	-1.218830796	4.42E-08	1.64E-07	down	yes	37.03750295	29.51285905	32.61397682	68.71165151	97.91260264	64.22851166	6	31229092	31246998	+	BAG3	protein_coding	GO:0007420|brain development; GO:0008625|extrinsic apoptotic signaling pathway via death domain receptors; GO:0010664|negative regulation of striated muscle cell apoptotic process; GO:0021510|spinal cord development; GO:0034605|cellular response to heat; GO:0046827|positive regulation of protein export from nucleus; GO:0050821|protein stabilization; GO:0071260|cellular response to mechanical stimulus; GO:0097192|extrinsic apoptotic signaling pathway in absence of ligand; GO:0097201|negative regulation of transcription from RNA polymerase II promoter in response to stress	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0030018|Z disc; GO:0043005|neuron projection	GO:0000774|adenyl-nucleotide exchange factor activity; GO:0044877|protein-containing complex binding; GO:0045296|cadherin binding; GO:0051087|chaperone binding	ko:K09557|BAG3	--	2262	XP_015144392.1	XP_015144392.1 BAG family molecular chaperone regulator 3 isoform X1 [Gallus gallus]	sp|Q9JLV1|BAG3_MOUSE	sp|Q9JLV1|BAG3_MOUSE BAG family molecular chaperone regulator 3 OS=Mus musculus GN=Bag3 PE=1 SV=2	_	_	_	_	_	PF02179.13|BAG|BAG domain|ENSGALT00000015358|m.5398:419-489;PF00397.23|WW|WW domain|ENSGALT00000015358|m.5398:28-58
ENSGALG00000009473	3.176259193	0.723566498	2.118863973	1.31E-08	5.11E-08	up	yes	4.000272482	3.528769545	1.999735551	0.681815034	0.791046573	0.697837887	2	22678104	22683834	-	EFCAB1	protein_coding	--	--	GO:0005509|calcium ion binding	--	--	843	XP_021244845.1	XP_021244845.1 EF-hand calcium-binding domain-containing protein 1 isoform X3 [Numida meleagris]	sp|Q3KQ77|EFCB1_XENLA	sp|Q3KQ77|EFCB1_XENLA EF-hand calcium-binding domain-containing protein 1 OS=Xenopus laevis GN=efcab1 PE=2 SV=1	9031.ENSGALP00000015408	annotation not avaliable	COG5126	KOG0044	_	PF00036.29|EF-hand_1|EF hand|ENSGALT00000015424|m.15135:131-157;PF13405.3|EF-hand_6|EF-hand domain|ENSGALT00000015424|m.15135:130-157;PF13499.3|EF-hand_7|EF-hand domain pair|ENSGALT00000015424|m.15135:128-200;PF13202.3|EF-hand_5|EF hand|ENSGALT00000015424|m.15135:134-151;PF13202.3|EF-hand_5|EF hand|ENSGALT00000015424|m.15135:176-198;PF13833.3|EF-hand_8|EF-hand domain pair|ENSGALT00000015424|m.15135:174-196
ENSGALG00000009476	47.27690426	23.3545584	1.017118926	3.61E-57	1.62E-55	up	yes	46.40079769	48.26619654	47.16371854	21.59389523	25.33948176	23.13029821	2	22703461	22836675	-	CDK6	protein_coding	GO:0000082|G1/S transition of mitotic cell cycle; GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0001954|positive regulation of cell-matrix adhesion; GO:0003323|type B pancreatic cell development; GO:0006468|protein phosphorylation; GO:0007050|cell cycle arrest; GO:0007165|signal transduction; GO:0007219|Notch signaling pathway; GO:0008285|negative regulation of cell population proliferation; GO:0009615|response to virus; GO:0010389|regulation of G2/M transition of mitotic cell cycle; GO:0010468|regulation of gene expression; GO:0010628|positive regulation of gene expression; GO:0014002|astrocyte development; GO:0021542|dentate gyrus development; GO:0021670|lateral ventricle development; GO:0033077|T cell differentiation in thymus; GO:0042063|gliogenesis; GO:0043697|cell dedifferentiation; GO:0045596|negative regulation of cell differentiation; GO:0045638|negative regulation of myeloid cell differentiation; GO:0045646|regulation of erythrocyte differentiation; GO:0045656|negative regulation of monocyte differentiation; GO:0045668|negative regulation of osteoblast differentiation; GO:0045786|negative regulation of cell cycle; GO:0048146|positive regulation of fibroblast proliferation; GO:0048699|generation of neurons; GO:0050680|negative regulation of epithelial cell proliferation; GO:0051301|cell division; GO:0060218|hematopoietic stem cell differentiation; GO:1902036|regulation of hematopoietic stem cell differentiation; GO:1904628|cellular response to phorbol 13-acetate 12-myristate; GO:2000145|regulation of cell motility; GO:2000773|negative regulation of cellular senescence	GO:0000307|cyclin-dependent protein kinase holoenzyme complex; GO:0001726|ruffle; GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005813|centrosome; GO:0005829|cytosol; GO:0097132|cyclin D2-CDK6 complex	GO:0004693|cyclin-dependent protein serine/threonine kinase activity; GO:0005524|ATP binding; GO:0030332|cyclin binding; GO:0098770|FBXO family protein binding	ko:K02091|CDK6	ko04110|Cell cycle; ko04115|p53 signaling pathway; ko04151|PI3K-Akt signaling pathway; ko05161|Hepatitis B; ko05162|Measles; ko05200|Pathways in cancer; ko05203|Viral carcinogenesis; ko05206|MicroRNAs in cancer; ko05212|Pancreatic cancer; ko05214|Glioma; ko05218|Melanoma; ko05220|Chronic myeloid leukemia; ko05222|Small cell lung cancer; ko05223|Non-small cell lung cancer; ko05224|Breast cancer	14621	NP_001007893.1	NP_001007893.1 cyclin-dependent kinase 6 [Gallus gallus]	sp|Q00534|CDK6_HUMAN	sp|Q00534|CDK6_HUMAN Cyclin-dependent kinase 6 OS=Homo sapiens GN=CDK6 PE=1 SV=1	9031.ENSGALP00000015412	cyclin-dependent kinase 6 	COG0515	KOG0594	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000015428|m.15141:13-300;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000015428|m.15141:16-214;PF06293.11|Kdo|Lipopolysaccharide kinase (Kdo/WaaP) family|ENSGALT00000015428|m.15141:56-164
ENSGALG00000009512	6.440599985	14.5707739	-1.176562035	7.20E-23	7.97E-22	down	yes	7.057290771	6.352925425	5.911583758	16.12590834	13.22063214	14.36578121	2	23301645	23311143	-	TFPI2	protein_coding	GO:0007596|blood coagulation	GO:0031012|extracellular matrix	GO:0004867|serine-type endopeptidase inhibitor activity	--	--	1805	XP_015137423.1	XP_015137423.1 tissue factor pathway inhibitor 2 isoform X1 [Gallus gallus]	sp|Q7YRQ8|TFPI2_BOVIN	sp|Q7YRQ8|TFPI2_BOVIN Tissue factor pathway inhibitor 2 OS=Bos taurus GN=TFPI2 PE=2 SV=1	9031.ENSGALP00000015469	tissue factor pathway inhibitor 2	_	KOG4295	_	PF00014.20|Kunitz_BPTI|Kunitz/Bovine pancreatic trypsin inhibitor domain|ENSGALT00000102159|m.6:71-122;PF00014.20|Kunitz_BPTI|Kunitz/Bovine pancreatic trypsin inhibitor domain|ENSGALT00000102159|m.6:132-182;PF00014.20|Kunitz_BPTI|Kunitz/Bovine pancreatic trypsin inhibitor domain|ENSGALT00000102159|m.6:192-243
ENSGALG00000009514	3.671550014	7.861862137	-1.096391654	2.69E-39	6.50E-38	down	yes	3.469704183	3.815985181	3.728960677	7.570218926	8.135133782	7.880233703	1	28704251	28843445	+	NRCAM	protein_coding	GO:0007156|homophilic cell adhesion via plasma membrane adhesion molecules; GO:0007158|neuron cell-cell adhesion; GO:0016338|calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules; GO:0016339|calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; GO:0045162|clustering of voltage-gated sodium channels	GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0005911|cell-cell junction	GO:0030246|carbohydrate binding; GO:0030247|polysaccharide binding; GO:0030506|ankyrin binding; GO:0046982|protein heterodimerization activity; GO:0050839|cell adhesion molecule binding	ko:K06756|NRCAM	ko04514|Cell adhesion molecules (CAMs)	7257	XP_021240621.1	XP_021240621.1 neuronal cell adhesion molecule isoform X1 [Numida meleagris]	sp|P35331|NRCAM_CHICK	sp|P35331|NRCAM_CHICK Neuronal cell adhesion molecule OS=Gallus gallus PE=1 SV=1	9031.ENSGALP00000015476	Neuronal cell adhesion molecule Precursor (Nr-CAM)(NgCAM-related cell adhesion molecule)(Ng- [...] 	_	KOG3513	_	PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000105834|m.721:40-122;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000105834|m.721:149-216;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000105834|m.721:243-320;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000105834|m.721:340-412;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000105834|m.721:429-505;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000105834|m.721:525-594;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000105834|m.721:42-127;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000105834|m.721:260-333;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000105834|m.721:340-425;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000105834|m.721:440-518;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000105834|m.721:524-609;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000105834|m.721:625-709;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000105834|m.721:725-806;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000105834|m.721:824-916;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000105834|m.721:929-1013;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000105834|m.721:1069-1136;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000105834|m.721:42-130;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000105834|m.721:261-325;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000105834|m.721:340-415;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000105834|m.721:260-325;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000105834|m.721:436-515;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000105834|m.721:532-605;PF11560.5|LAP2alpha|Lamina-associated polypeptide 2 alpha|ENSGALT00000105834|m.721:1563-1765;PF13882.3|Bravo_FIGEY|Bravo-like intracellular region|ENSGALT00000105834|m.721:1189-1248
ENSGALG00000009556	3.348501702	15.98341622	-2.251588469	6.61E-89	6.34E-87	down	yes	3.600799015	2.985047825	3.459658265	15.15740993	17.31823566	15.47460307	1	29774813	29833578	-	PRICKLE1	protein_coding	"GO:0001843|neural tube closure; GO:0006606|protein import into nucleus; GO:0031398|positive regulation of protein ubiquitination; GO:0032436|positive regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0035904|aorta development; GO:0045892|negative regulation of transcription, DNA-templated; GO:0060071|Wnt signaling pathway, planar cell polarity pathway; GO:0060976|coronary vasculature development; GO:0090090|negative regulation of canonical Wnt signaling pathway; GO:2000691|negative regulation of cardiac muscle cell myoblast differentiation"	GO:0005634|nucleus; GO:0005829|cytosol; GO:0031965|nuclear membrane	GO:0008270|zinc ion binding	ko:K04511|PRICKLE	ko04310|Wnt signaling pathway	2762	XP_416036.2	XP_416036.2 prickle-like protein 1 [Gallus gallus]	sp|Q96MT3|PRIC1_HUMAN	sp|Q96MT3|PRIC1_HUMAN Prickle-like protein 1 OS=Homo sapiens GN=PRICKLE1 PE=1 SV=2	9031.ENSGALP00000015542	prickle homolog 1 (Drosophila)	_	KOG1704	_	PF06297.11|PET|PET Domain|ENSGALT00000015558|m.742:27-111;PF00412.19|LIM|LIM domain|ENSGALT00000015558|m.742:122-181;PF00412.19|LIM|LIM domain|ENSGALT00000015558|m.742:187-241;PF00412.19|LIM|LIM domain|ENSGALT00000015558|m.742:247-300
ENSGALG00000009560	151.3994112	31.04574967	2.285522583	0	0	up	yes	150.1823313	154.9058764	149.110026	31.73485718	30.96227621	30.44011564	4	23878783	23885142	+	MSMO1	protein_coding	GO:0016126|sterol biosynthetic process	GO:0005789|endoplasmic reticulum membrane; GO:0016021|integral component of membrane	GO:0000254|C-4 methylsterol oxidase activity; GO:0005506|iron ion binding	"ko:K07750|E1.14.13.72,SC4MOL,ERG25"	ko00100|Steroid biosynthesis; ko01100|Metabolic pathways; ko01130|Biosynthesis of antibiotics	1863	XP_021250588.1	XP_021250588.1 methylsterol monooxygenase 1 [Numida meleagris]	sp|Q5ZLL6|MSMO1_CHICK	sp|Q5ZLL6|MSMO1_CHICK Methylsterol monooxygenase 1 OS=Gallus gallus GN=MSMO1 PE=2 SV=1	9031.ENSGALP00000015550	C-4 methylsterol oxidase (EC 1.14.13.72)(Methylsterol monooxygenase)	COG3000	KOG0873	_	PF04116.10|FA_hydroxylase|Fatty acid hydroxylase superfamily|ENSGALT00000015566|m.16801:145-274
ENSGALG00000009562	1.153910853	0.464015256	1.295975164	0.000732601	0.001573413	up	yes	0.893069307	1.269913583	1.298749668	0.254489698	0.503050466	0.634505604	5	29157311	29169648	-	PLEK2	protein_coding	GO:0030036|actin cytoskeleton organization; GO:0031346|positive regulation of cell projection organization; GO:0035556|intracellular signal transduction	GO:0005737|cytoplasm; GO:0005856|cytoskeleton; GO:0005886|plasma membrane; GO:0016020|membrane; GO:0031258|lamellipodium membrane	"GO:0043325|phosphatidylinositol-3,4-bisphosphate binding; GO:0080025|phosphatidylinositol-3,5-bisphosphate binding"	ko:K19993|PLEK	--	1947	NP_001264366.1	NP_001264366.1 pleckstrin-2 [Gallus gallus]	sp|Q9WV52|PLEK2_MOUSE	sp|Q9WV52|PLEK2_MOUSE Pleckstrin-2 OS=Mus musculus GN=Plek2 PE=1 SV=1	9031.ENSGALP00000015553	pleckstrin 2	_	_	NOG44162	"PF00169.26|PH|PH domain|ENSGALT00000015569|m.3266:7-105;PF00169.26|PH|PH domain|ENSGALT00000015569|m.3266:251-352;PF00610.18|DEP|Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)|ENSGALT00000015569|m.3266:146-225"
ENSGALG00000009577	5.437334889	11.45206881	-1.073244994	7.10E-17	5.40E-16	down	yes	5.892224709	5.275977256	5.143802702	10.6600534	12.85818854	10.83796449	1	30181037	30190843	-	PUS7L	protein_coding	GO:0001522|pseudouridine synthesis; GO:0008033|tRNA processing	--	GO:0003723|RNA binding; GO:0009982|pseudouridine synthase activity	"ko:K06176|truD,PUS7"	--	2021	XP_416038.1	XP_416038.1 pseudouridylate synthase 7 homolog-like protein [Gallus gallus]	sp|Q9H0K6|PUS7L_HUMAN	sp|Q9H0K6|PUS7L_HUMAN Pseudouridylate synthase 7 homolog-like protein OS=Homo sapiens GN=PUS7L PE=1 SV=1	9031.ENSGALP00000015589	pseudouridylate synthase 7 homolog (S. cerevisiae)-like	COG0585	KOG2339	_	PF01142.15|TruD|tRNA pseudouridine synthase D (TruD)|ENSGALT00000015605|m.746:268-667
ENSGALG00000009581	8.685821367	17.94588189	-1.046062303	4.74E-38	1.10E-36	down	yes	9.51824847	8.292347458	8.246868175	17.46312769	17.86149314	18.51302485	5	29189427	29237604	-	MPP5	protein_coding	GO:0002011|morphogenesis of an epithelial sheet; GO:0032287|peripheral nervous system myelin maintenance; GO:0032288|myelin assembly; GO:0035750|protein localization to myelin sheath abaxonal region; GO:0070830|bicellular tight junction assembly; GO:0072659|protein localization to plasma membrane; GO:0090162|establishment of epithelial cell polarity	GO:0005737|cytoplasm; GO:0005886|plasma membrane; GO:0005923|bicellular tight junction; GO:0012505|endomembrane system; GO:0032991|protein-containing complex; GO:0035749|myelin sheath adaxonal region; GO:0043219|lateral loop; GO:0043220|Schmidt-Lanterman incisure; GO:0070062|extracellular exosome	GO:0019904|protein domain specific binding	"ko:K06091|MPP5,PALS1"	ko04390|Hippo signaling pathway; ko04391|Hippo signaling pathway - fly; ko04530|Tight junction	4794	NP_001186634.1	NP_001186634.1 MAGUK p55 subfamily member 5 [Gallus gallus]	sp|Q8N3R9|MPP5_HUMAN	sp|Q8N3R9|MPP5_HUMAN MAGUK p55 subfamily member 5 OS=Homo sapiens GN=MPP5 PE=1 SV=3	9031.ENSGALP00000015593	"membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)"	COG0194	KOG0609	_	PF00625.18|Guanylate_kin|Guanylate kinase|ENSGALT00000015609|m.3274:479-661;PF09060.7|L27_N|L27_N|ENSGALT00000015609|m.3274:123-170;PF07653.14|SH3_2|Variant SH3 domain|ENSGALT00000015609|m.3274:349-411;PF00595.21|PDZ|PDZ domain (Also known as DHR or GLGF)|ENSGALT00000015609|m.3274:258-331;PF02828.13|L27|L27 domain|ENSGALT00000015609|m.3274:186-235;PF00018.25|SH3_1|SH3 domain|ENSGALT00000015609|m.3274:370-397
ENSGALG00000009596	0.222759983	1.091833056	-2.242990701	8.83E-10	3.84E-09	down	yes	0.150117063	0.275164902	0.242997983	1.11520866	1.224521713	0.935768796	1	30234476	30430729	+	TMEM117	protein_coding	GO:0070059|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	GO:0005783|endoplasmic reticulum; GO:0005886|plasma membrane; GO:0016021|integral component of membrane	--	--	--	2682	XP_416041.3	XP_416041.3 transmembrane protein 117 isoform X1 [Gallus gallus]	sp|Q9H0C3|TM117_HUMAN	sp|Q9H0C3|TM117_HUMAN Transmembrane protein 117 OS=Homo sapiens GN=TMEM117 PE=1 SV=1	9031.ENSGALP00000015620	transmembrane protein 117	_	_	NOG46585	PF15113.3|TMEM117|TMEM117 protein family|ENSGALT00000106807|m.753:4-416
ENSGALG00000009601	0.908623688	0.431220025	1.057975716	0.000511352	0.00112544	up	yes	1.023280786	0.623301531	1.079288746	0.438199782	0.398477598	0.456982695	1	30463434	30606675	-	NELL2	protein_coding	--	GO:0005623|cell	GO:0005509|calcium ion binding	--	--	3061	NP_001025911.1	NP_001025911.1 protein NEL precursor [Gallus gallus]	sp|Q90827|NEL_CHICK	sp|Q90827|NEL_CHICK Protein NEL OS=Gallus gallus GN=NEL PE=2 SV=1	9031.ENSGALP00000037995	Protein NEL Precursor (93 kDa protein)	_	KOG1217	_	PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000038787|m.756:440-473;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000038787|m.756:484-521;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000038787|m.756:555-590;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000038787|m.756:602-633;PF00093.15|VWC|von Willebrand factor type C domain|ENSGALT00000038787|m.756:274-330;PF00093.15|VWC|von Willebrand factor type C domain|ENSGALT00000038787|m.756:705-755;PF12947.4|EGF_3|EGF domain|ENSGALT00000038787|m.756:486-521;PF12662.4|cEGF|Complement Clr-like EGF-like|ENSGALT00000038787|m.756:578-605;PF02210.21|Laminin_G_2|Laminin G domain|ENSGALT00000038787|m.756:100-210;PF00054.20|Laminin_G_1|Laminin G domain|ENSGALT00000038787|m.756:99-210
ENSGALG00000009602	0.218066034	0.490083983	-1.132718798	0.004408797	0.008347147	down	yes	0.177273333	0.289948607	0.186976161	0.35905177	0.598639695	0.512560483	7	18273898	18440953	-	MYO3B	protein_coding	GO:0007601|visual perception; GO:0007605|sensory perception of sound; GO:0050896|response to stimulus; GO:0090103|cochlea morphogenesis	GO:0005737|cytoplasm; GO:0016459|myosin complex; GO:0032426|stereocilium tip	GO:0003774|motor activity; GO:0003779|actin binding; GO:0004674|protein serine/threonine kinase activity; GO:0005524|ATP binding	"ko:K08834|MYO3,DFNB30"	ko04745|Phototransduction - fly	3864	XP_015145166.2	XP_015145166.2 myosin-IIIb isoform X3 [Gallus gallus]	sp|Q8WXR4|MYO3B_HUMAN	sp|Q8WXR4|MYO3B_HUMAN Myosin-IIIb OS=Homo sapiens GN=MYO3B PE=2 SV=4	9031.ENSGALP00000015632	myosin IIIB	COG0515;COG5022	KOG0587;KOG4229	_	PF00063.18|Myosin_head|Myosin head (motor domain)|ENSGALT00000015648|m.6167:345-1045;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000015648|m.6167:27-292;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000015648|m.6167:28-288;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000015648|m.6167:1089-1107
ENSGALG00000009610	2.201889042	4.762707872	-1.109529019	0.000219991	0.000512168	down	yes	1.892639695	1.887251693	2.825775739	5.239679623	4.850487889	4.197956103	6	32384001	32386306	+	PSTK	protein_coding	GO:0001514|selenocysteine incorporation; GO:0016259|selenocysteine metabolic process; GO:0097056|selenocysteinyl-tRNA(Sec) biosynthetic process	GO:0005739|mitochondrion; GO:0005829|cytosol	GO:0000049|tRNA binding; GO:0005524|ATP binding; GO:0016301|kinase activity; GO:0098620|seryl-selenocysteinyl-tRNA kinase activity	ko:K10837|PSTK	ko00450|Selenocompound metabolism; ko00970|Aminoacyl-tRNA biosynthesis	696	XP_001235013.3	XP_001235013.3 L-seryl-tRNA(Sec) kinase isoform X2 [Gallus gallus]	sp|Q8BP74|PSTK_MOUSE	sp|Q8BP74|PSTK_MOUSE L-seryl-tRNA(Sec) kinase OS=Mus musculus GN=Pstk PE=1 SV=2	9031.ENSGALP00000028635	phosphoseryl-tRNA kinase	COG4088	KOG4622	_	PF08433.7|KTI12|Chromatin associated protein KTI12|ENSGALT00000029296|m.5446:11-169
ENSGALG00000009626	5.969445756	17.18863189	-1.524210137	1.40E-43	4.05E-42	down	yes	5.89851865	5.588078585	6.421740032	14.56549753	20.62010323	16.38029493	5	29833567	29849200	-	THBS1	protein_coding	GO:0000187|activation of MAPK activity; GO:0001666|response to hypoxia; GO:0001937|negative regulation of endothelial cell proliferation; GO:0001953|negative regulation of cell-matrix adhesion; GO:0002040|sprouting angiogenesis; GO:0002544|chronic inflammatory response; GO:0002576|platelet degranulation; GO:0002581|negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0002605|negative regulation of dendritic cell antigen processing and presentation; GO:0006954|inflammatory response; GO:0006955|immune response; GO:0006986|response to unfolded protein; GO:0007050|cell cycle arrest; GO:0007155|cell adhesion; GO:0008284|positive regulation of cell population proliferation; GO:0009612|response to mechanical stimulus; GO:0009749|response to glucose; GO:0010595|positive regulation of endothelial cell migration; GO:0010596|negative regulation of endothelial cell migration; GO:0010748|negative regulation of long-chain fatty acid import across plasma membrane; GO:0010751|negative regulation of nitric oxide mediated signal transduction; GO:0010754|negative regulation of cGMP-mediated signaling; GO:0010757|negative regulation of plasminogen activation; GO:0010759|positive regulation of macrophage chemotaxis; GO:0010763|positive regulation of fibroblast migration; GO:0016477|cell migration; GO:0016525|negative regulation of angiogenesis; GO:0018149|peptide cross-linking; GO:0030194|positive regulation of blood coagulation; GO:0030198|extracellular matrix organization; GO:0030335|positive regulation of cell migration; GO:0030511|positive regulation of transforming growth factor beta receptor signaling pathway; GO:0032026|response to magnesium ion; GO:0032570|response to progesterone; GO:0032695|negative regulation of interleukin-12 production; GO:0032914|positive regulation of transforming growth factor beta1 production; GO:0033574|response to testosterone; GO:0034605|cellular response to heat; GO:0034976|response to endoplasmic reticulum stress; GO:0036066|protein O-linked fucosylation; GO:0040037|negative regulation of fibroblast growth factor receptor signaling pathway; GO:0042327|positive regulation of phosphorylation; GO:0042493|response to drug; GO:0042535|positive regulation of tumor necrosis factor biosynthetic process; GO:0043032|positive regulation of macrophage activation; GO:0043066|negative regulation of apoptotic process; GO:0043154|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0043536|positive regulation of blood vessel endothelial cell migration; GO:0043537|negative regulation of blood vessel endothelial cell migration; GO:0043652|engulfment of apoptotic cell; GO:0045652|regulation of megakaryocyte differentiation; GO:0045727|positive regulation of translation; GO:0045766|positive regulation of angiogenesis; GO:0048266|behavioral response to pain; GO:0048661|positive regulation of smooth muscle cell proliferation; GO:0050921|positive regulation of chemotaxis; GO:0051592|response to calcium ion; GO:0051895|negative regulation of focal adhesion assembly; GO:0051897|positive regulation of protein kinase B signaling; GO:0051918|negative regulation of fibrinolysis; GO:0071356|cellular response to tumor necrosis factor; GO:0071363|cellular response to growth factor stimulus; GO:1902043|positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; GO:2000353|positive regulation of endothelial cell apoptotic process; GO:2000379|positive regulation of reactive oxygen species metabolic process; GO:2001027|negative regulation of endothelial cell chemotaxis; GO:2001237|negative regulation of extrinsic apoptotic signaling pathway	GO:0005576|extracellular region; GO:0005577|fibrinogen complex; GO:0005615|extracellular space; GO:0005783|endoplasmic reticulum; GO:0005788|endoplasmic reticulum lumen; GO:0009897|external side of plasma membrane; GO:0009986|cell surface; GO:0016529|sarcoplasmic reticulum; GO:0030141|secretory granule; GO:0031012|extracellular matrix; GO:0031091|platelet alpha granule; GO:0031093|platelet alpha granule lumen; GO:0070062|extracellular exosome	GO:0001786|phosphatidylserine binding; GO:0001968|fibronectin binding; GO:0005178|integrin binding; GO:0005509|calcium ion binding; GO:0008201|heparin binding; GO:0017134|fibroblast growth factor binding; GO:0030169|low-density lipoprotein particle binding; GO:0042802|identical protein binding; GO:0043236|laminin binding; GO:0043394|proteoglycan binding; GO:0050431|transforming growth factor beta binding; GO:0070051|fibrinogen binding; GO:0070052|collagen V binding	ko:K16857|THBS1	ko04015|Rap1 signaling pathway; ko04115|p53 signaling pathway; ko04145|Phagosome; ko04151|PI3K-Akt signaling pathway; ko04350|TGF-beta signaling pathway; ko04510|Focal adhesion; ko04512|ECM-receptor interaction; ko05144|Malaria; ko05205|Proteoglycans in cancer; ko05206|MicroRNAs in cancer; ko05219|Bladder cancer	5994	NP_001186382.1	NP_001186382.1 thrombospondin-1 precursor [Gallus gallus]	sp|P07996|TSP1_HUMAN	sp|P07996|TSP1_HUMAN Thrombospondin-1 OS=Homo sapiens GN=THBS1 PE=1 SV=2	_	_	_	_	_	PF05735.9|TSP_C|Thrombospondin C-terminal region|ENSGALT00000015678|m.3297:980-1177;PF02412.15|TSP_3|Thrombospondin type 3 repeat|ENSGALT00000015678|m.3297:735-770;PF02412.15|TSP_3|Thrombospondin type 3 repeat|ENSGALT00000015678|m.3297:771-793;PF02412.15|TSP_3|Thrombospondin type 3 repeat|ENSGALT00000015678|m.3297:795-829;PF02412.15|TSP_3|Thrombospondin type 3 repeat|ENSGALT00000015678|m.3297:830-852;PF02412.15|TSP_3|Thrombospondin type 3 repeat|ENSGALT00000015678|m.3297:853-890;PF02412.15|TSP_3|Thrombospondin type 3 repeat|ENSGALT00000015678|m.3297:892-926;PF02412.15|TSP_3|Thrombospondin type 3 repeat|ENSGALT00000015678|m.3297:928-960;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000015678|m.3297:391-436;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000015678|m.3297:447-497;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000015678|m.3297:504-554;PF00093.15|VWC|von Willebrand factor type C domain|ENSGALT00000015678|m.3297:326-380
ENSGALG00000009686	11.50037007	44.72885547	-1.958594131	8.48E-105	1.18E-102	down	yes	11.28102417	12.29144061	10.92864542	40.12008756	42.13248542	51.93399343	2	23715866	23846194	+	PPP1R9A	protein_coding	GO:0007015|actin filament organization; GO:0007568|aging; GO:0019722|calcium-mediated signaling; GO:0030833|regulation of actin filament polymerization; GO:0031175|neuron projection development; GO:0045860|positive regulation of protein kinase activity; GO:0051489|regulation of filopodium assembly; GO:0051497|negative regulation of stress fiber assembly; GO:0051823|regulation of synapse structural plasticity; GO:0051963|regulation of synapse assembly; GO:0060079|excitatory postsynaptic potential; GO:0060999|positive regulation of dendritic spine development; GO:0061001|regulation of dendritic spine morphogenesis; GO:0097237|cellular response to toxic substance; GO:1900272|negative regulation of long-term synaptic potentiation; GO:1900454|positive regulation of long-term synaptic depression; GO:1904049|negative regulation of spontaneous neurotransmitter secretion	GO:0005829|cytosol; GO:0014069|postsynaptic density; GO:0030054|cell junction; GO:0030175|filopodium; GO:0030864|cortical actin cytoskeleton; GO:0031594|neuromuscular junction; GO:0043025|neuronal cell body; GO:0044326|dendritic spine neck; GO:1990761|growth cone lamellipodium	GO:0008022|protein C-terminus binding; GO:0008157|protein phosphatase 1 binding; GO:0019901|protein kinase binding; GO:0019904|protein domain specific binding; GO:0042803|protein homodimerization activity; GO:0044325|ion channel binding; GO:0051015|actin filament binding; GO:0051020|GTPase binding	ko:K17551|PPP1R9	--	4922	XP_015137405.1	XP_015137405.1 neurabin-1 isoform X1 [Gallus gallus]	sp|Q9ULJ8|NEB1_HUMAN	sp|Q9ULJ8|NEB1_HUMAN Neurabin-1 OS=Homo sapiens GN=PPP1R9A PE=1 SV=2	_	_	_	_	_	PF07647.14|SAM_2|SAM domain (Sterile alpha motif)|ENSGALT00000095167|m.31:1230-1293;PF00595.21|PDZ|PDZ domain (Also known as DHR or GLGF)|ENSGALT00000095167|m.31:529-610;PF00536.27|SAM_1|SAM domain (Sterile alpha motif)|ENSGALT00000095167|m.31:1231-1289
ENSGALG00000009700	10.37648774	76.84895799	-2.887505538	5.45E-53	2.19E-51	down	yes	9.804615045	9.213464854	12.11138332	70.65933552	92.13235603	67.75518243	2	23905072	23914501	-	PDK4	protein_coding	GO:0006006|glucose metabolic process; GO:0006885|regulation of pH; GO:0008286|insulin receptor signaling pathway; GO:0009267|cellular response to starvation; GO:0010510|regulation of acetyl-CoA biosynthetic process from pyruvate; GO:0010565|regulation of cellular ketone metabolic process; GO:0010906|regulation of glucose metabolic process; GO:0042304|regulation of fatty acid biosynthetic process; GO:0042593|glucose homeostasis; GO:0042594|response to starvation; GO:0045124|regulation of bone resorption; GO:0046320|regulation of fatty acid oxidation; GO:0071398|cellular response to fatty acid; GO:0072593|reactive oxygen species metabolic process; GO:2000811|negative regulation of anoikis	GO:0005739|mitochondrion; GO:0005743|mitochondrial inner membrane; GO:0005759|mitochondrial matrix	GO:0004672|protein kinase activity; GO:0004712|protein serine/threonine/tyrosine kinase activity; GO:0004740|pyruvate dehydrogenase (acetyl-transferring) kinase activity; GO:0005524|ATP binding	ko:K00898|PDK2_3_4	--	3729	NP_001186838.1	"NP_001186838.1 pyruvate dehydrogenase kinase, isozyme 4 [Gallus gallus]"	sp|O70571|PDK4_MOUSE	"sp|O70571|PDK4_MOUSE [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial OS=Mus musculus GN=Pdk4 PE=1 SV=1"	_	_	_	_	_	"PF10436.6|BCDHK_Adom3|Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase|ENSGALT00000015790|m.50:66-228;PF02518.23|HATPase_c|Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase|ENSGALT00000015790|m.50:278-398"
ENSGALG00000009719	0.551782889	0	5.811940778	3.40E-14	2.14E-13	up	yes	0.4317029	0.530393145	0.693252622	0	0	0	4	26882271	26914396	+	PCDH10	protein_coding	GO:0007155|cell adhesion; GO:0007156|homophilic cell adhesion via plasma membrane adhesion molecules; GO:0007267|cell-cell signaling; GO:0007399|nervous system development	GO:0005887|integral component of plasma membrane	GO:0005509|calcium ion binding	ko:K16499|PCDHD2	--	4516	NP_999837.1	NP_999837.1 protocadherin-10 precursor [Gallus gallus]	sp|Q9P2E7|PCD10_HUMAN	sp|Q9P2E7|PCD10_HUMAN Protocadherin-10 OS=Homo sapiens GN=PCDH10 PE=2 SV=2	28377.ENSACAP00000013606	protocadherin 10	_	KOG3594	_	PF00028.14|Cadherin|Cadherin domain|ENSGALT00000015818|m.9:128-223;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000015818|m.9:237-330;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000015818|m.9:349-438;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000015818|m.9:453-550;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000015818|m.9:580-663;PF08266.9|Cadherin_2|Cadherin-like|ENSGALT00000015818|m.9:19-101;PF16492.2|Cadherin_C_2|Cadherin cytoplasmic C-terminal|ENSGALT00000015818|m.9:707-828
ENSGALG00000009730	6.524044769	13.89504493	-1.089560161	2.14E-22	2.31E-21	down	yes	6.004369868	7.322022616	6.245741823	13.1384104	15.80450771	12.74221667	1	31222996	31253936	-	SLC38A4	protein_coding	GO:0006814|sodium ion transport; GO:0006865|amino acid transport	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0015293|symporter activity	"ko:K14991|SLC38A4,SNAT4"	--	3027	NP_001186478.1	NP_001186478.1 sodium-coupled neutral amino acid transporter 4 [Gallus gallus]	sp|Q5RE87|S38A4_PONAB	sp|Q5RE87|S38A4_PONAB Sodium-coupled neutral amino acid transporter 4 OS=Pongo abelii GN=SLC38A4 PE=2 SV=1	9031.ENSGALP00000015821	"solute carrier family 38, member 4"	_	KOG1305	_	PF01490.15|Aa_trans|Transmembrane amino acid transporter protein|ENSGALT00000015837|m.781:82-253;PF01490.15|Aa_trans|Transmembrane amino acid transporter protein|ENSGALT00000015837|m.781:333-542
ENSGALG00000009752	37.21527911	17.17749679	1.114923222	1.95E-75	1.39E-73	up	yes	36.55530672	37.69791359	37.39261701	16.6569889	17.03453047	17.840971	2	24691867	24702573	+	C1GALT1	protein_coding	"GO:0001525|angiogenesis; GO:0001822|kidney development; GO:0016267|O-glycan processing, core 1; GO:0060576|intestinal epithelial cell development"	GO:0016021|integral component of membrane	GO:0016263|glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity; GO:0046872|metal ion binding	ko:K00731|C1GALT1	ko00512|Mucin type O-glycan biosynthesis; ko01100|Metabolic pathways	4956	XP_015136884.1	XP_015136884.1 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 isoform X1 [Gallus gallus]	sp|Q5F3G7|C1GLT_CHICK	sp|Q5F3G7|C1GLT_CHICK Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 OS=Gallus gallus GN=C1GALT1 PE=2 SV=1	9031.ENSGALP00000015853	Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 (EC 2.4.1.122)(Core 1 beta [...] 	_	KOG2246	_	PF02434.13|Fringe|Fringe-like|ENSGALT00000015869|m.76:100-261;PF01762.18|Galactosyl_T|Galactosyltransferase|ENSGALT00000015869|m.76:123-202
ENSGALG00000009755	1.897595117	3.954885556	-1.055524229	1.55E-13	9.23E-13	down	yes	2.158950385	1.666747231	1.867087734	4.12730399	3.691675794	4.045676884	1	31842742	31886512	-	LRIG3	protein_coding	GO:0032474|otolith morphogenesis	GO:0005615|extracellular space; GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0030659|cytoplasmic vesicle membrane	--	--	--	4073	NP_001186484.1	NP_001186484.1 leucine-rich repeats and immunoglobulin-like domains protein 3 precursor [Gallus gallus]	sp|Q6UXM1|LRIG3_HUMAN	sp|Q6UXM1|LRIG3_HUMAN Leucine-rich repeats and immunoglobulin-like domains protein 3 OS=Homo sapiens GN=LRIG3 PE=2 SV=1	9031.ENSGALP00000015856	leucine-rich repeats and immunoglobulin-like domains 3	COG4886	KOG2408;KOG4194	_	PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000015872|m.790:100-158;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000015872|m.790:124-170;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000015872|m.790:147-206;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000015872|m.790:172-230;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000015872|m.790:194-254;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000015872|m.790:218-278;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000015872|m.790:243-302;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000015872|m.790:291-350;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000015872|m.790:366-422;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000015872|m.790:478-578;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000015872|m.790:582-672;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000015872|m.790:676-763;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000015872|m.790:477-564;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000015872|m.790:582-659;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000015872|m.790:679-750;PF12799.4|LRR_4|Leucine Rich repeats (2 copies)|ENSGALT00000015872|m.790:172-212;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000015872|m.790:62-169;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000015872|m.790:104-218;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000015872|m.790:208-319;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000015872|m.790:317-422;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000015872|m.790:592-669;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000015872|m.790:685-753;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000015872|m.790:485-570;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000015872|m.790:591-667;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000015872|m.790:686-753
ENSGALG00000009787	4.835691412	1.109964669	2.113249311	2.65E-15	1.80E-14	up	yes	5.049562706	5.151086973	4.306424557	1.21808313	1.17220124	0.939609638	6	34219436	34227592	-	CLRN3	protein_coding	--	GO:0016021|integral component of membrane; GO:0070062|extracellular exosome	--	--	--	960	XP_004942413.1	XP_004942413.1 clarin-3 [Gallus gallus]	sp|Q8BHH8|CLRN3_MOUSE	sp|Q8BHH8|CLRN3_MOUSE Clarin-3 OS=Mus musculus GN=Clrn3 PE=1 SV=1	_	_	_	_	_	_
ENSGALG00000009905	4.439352462	10.32220483	-1.215480856	2.09E-33	3.93E-32	down	yes	4.255122316	4.580219087	4.482715984	10.4774021	10.62843532	9.860777075	1	35233248	35257392	-	MDM1	protein_coding	GO:0046600|negative regulation of centriole replication; GO:0060041|retina development in camera-type eye	GO:0005634|nucleus; GO:0005813|centrosome; GO:0005814|centriole; GO:0005874|microtubule	GO:0008017|microtubule binding	ko:K17886|MDM1	--	3351	NP_001025913.1	NP_001025913.1 nuclear protein MDM1 [Gallus gallus]	sp|Q5ZMW6|MDM1_CHICK	sp|Q5ZMW6|MDM1_CHICK Nuclear protein MDM1 OS=Gallus gallus GN=MDM1 PE=2 SV=1	9031.ENSGALP00000016088	Nuclear protein MDM1 	_	_	NOG72701	PF15501.3|MDM1|Nuclear protein MDM1|ENSGALT00000081470|m.862:9-514
ENSGALG00000009945	0.225762729	0.609257119	-1.393202881	0.007349395	0.013329742	down	yes	0.14357245	0.336855824	0.196859915	0.594049686	0.624606171	0.6091155	1	35432767	35464430	-	CPM	protein_coding	GO:0006501|C-terminal protein lipidation; GO:0006518|peptide metabolic process; GO:0009653|anatomical structure morphogenesis; GO:0016485|protein processing	GO:0005576|extracellular region; GO:0005615|extracellular space; GO:0005886|plasma membrane; GO:0009986|cell surface; GO:0031225|anchored component of membrane; GO:0070062|extracellular exosome	GO:0004180|carboxypeptidase activity; GO:0004181|metallocarboxypeptidase activity; GO:0004185|serine-type carboxypeptidase activity; GO:0008270|zinc ion binding	ko:K01296|CPM	--	1835	NP_001186554.1	NP_001186554.1 carboxypeptidase M precursor [Gallus gallus]	sp|P14384|CBPM_HUMAN	sp|P14384|CBPM_HUMAN Carboxypeptidase M OS=Homo sapiens GN=CPM PE=1 SV=2	9031.ENSGALP00000016151	carboxypeptidase M	COG2866	KOG2649	_	PF00246.21|Peptidase_M14|Zinc carboxypeptidase|ENSGALT00000016170|m.871:32-304;PF13620.3|CarboxypepD_reg|Carboxypeptidase regulatory-like domain|ENSGALT00000016170|m.871:318-385;PF04952.11|AstE_AspA|Succinylglutamate desuccinylase / Aspartoacylase family|ENSGALT00000016170|m.871:82-167
ENSGALG00000009954	1.357513539	3.326108767	-1.286611209	7.36E-10	3.21E-09	down	yes	1.555226951	1.474779918	1.042533747	3.853172336	3.100036337	3.025117627	3	25309379	25331245	+	DYNC2LI1	protein_coding	GO:0007368|determination of left/right symmetry; GO:0035721|intraciliary retrograde transport; GO:0035735|intraciliary transport involved in cilium assembly; GO:1902017|regulation of cilium assembly	GO:0005737|cytoplasm; GO:0005813|centrosome; GO:0005868|cytoplasmic dynein complex; GO:0005874|microtubule; GO:0005930|axoneme; GO:0030990|intraciliary transport particle; GO:0031514|motile cilium; GO:0035869|ciliary transition zone; GO:0036064|ciliary basal body; GO:0045177|apical part of cell	"GO:0008569|ATP-dependent microtubule motor activity, minus-end-directed; GO:0045504|dynein heavy chain binding"	ko:K10417|DYNC2LI	ko04962|Vasopressin-regulated water reabsorption	2541	XP_419456.3	XP_419456.3 cytoplasmic dynein 2 light intermediate chain 1 [Gallus gallus]	sp|Q32KV4|DC2L1_BOVIN	sp|Q32KV4|DC2L1_BOVIN Cytoplasmic dynein 2 light intermediate chain 1 OS=Bos taurus GN=DYNC2LI1 PE=2 SV=1	9031.ENSGALP00000016162	"dynein, cytoplasmic 2, light intermediate chain 1"	_	KOG3929	_	PF05783.8|DLIC|Dynein light intermediate chain (DLIC)|ENSGALT00000016181|m.11291:50-187;PF05783.8|DLIC|Dynein light intermediate chain (DLIC)|ENSGALT00000016181|m.11291:200-288
ENSGALG00000009955	0.989447616	0.282792217	1.77125375	6.87E-06	1.98E-05	up	yes	0.723702228	1.163280339	1.081360281	0.261749309	0.286221586	0.300405755	3	25331747	25347053	-	ABCG5	protein_coding	GO:0006855|drug transmembrane transport; GO:0007584|response to nutrient; GO:0007588|excretion; GO:0010212|response to ionizing radiation; GO:0010949|negative regulation of intestinal phytosterol absorption; GO:0030299|intestinal cholesterol absorption; GO:0033344|cholesterol efflux; GO:0042632|cholesterol homeostasis; GO:0045796|negative regulation of intestinal cholesterol absorption; GO:0055085|transmembrane transport	GO:0005886|plasma membrane; GO:0016324|apical plasma membrane; GO:0043190|ATP-binding cassette (ABC) transporter complex; GO:0043235|receptor complex	GO:0005524|ATP binding; GO:0042626|ATPase-coupled transmembrane transporter activity; GO:0046982|protein heterodimerization activity; GO:0120020|cholesterol transfer activity	ko:K05683|ABCG5	ko02010|ABC transporters; ko04975|Fat digestion and absorption; ko04976|Bile secretion	1893	XP_419457.3	XP_419457.3 ATP-binding cassette sub-family G member 5 [Gallus gallus]	sp|Q9H222|ABCG5_HUMAN	sp|Q9H222|ABCG5_HUMAN ATP-binding cassette sub-family G member 5 OS=Homo sapiens GN=ABCG5 PE=1 SV=1	9031.ENSGALP00000016163	"ATP-binding cassette, sub-family G (WHITE), member 5 (sterolin 1)"	COG1131	KOG0061	_	PF00005.24|ABC_tran|ABC transporter|ENSGALT00000016182|m.11293:60-211;PF01061.21|ABC2_membrane|ABC-2 type transporter|ENSGALT00000016182|m.11293:359-477
ENSGALG00000009993	5.089862743	11.89785015	-1.223382647	1.08E-26	1.46E-25	down	yes	5.188192152	5.07779915	5.003596928	12.61332326	11.53964645	11.54058073	8	20059234	20069284	-	MED8	protein_coding	GO:0006367|transcription initiation from RNA polymerase II promoter; GO:0016567|protein ubiquitination	GO:0005654|nucleoplasm; GO:0016592|mediator complex	GO:0003712|transcription coregulator activity	ko:K15129|MED8	ko05168|Herpes simplex infection	2214	NP_001264497.1	NP_001264497.1 mediator of RNA polymerase II transcription subunit 8 [Gallus gallus]	sp|Q96G25|MED8_HUMAN	sp|Q96G25|MED8_HUMAN Mediator of RNA polymerase II transcription subunit 8 OS=Homo sapiens GN=MED8 PE=1 SV=2	9031.ENSGALP00000016218	"mediator of RNA polymerase II transcription, subunit 8 homolog (S. cerevisiae)"	_	KOG3583	_	PF10232.6|Med8|Mediator of RNA polymerase II transcription complex subunit 8|ENSGALT00000016237|m.7682:1-265
ENSGALG00000010020	18.31674792	9.09852555	1.008661362	1.41E-32	2.55E-31	up	yes	17.88781751	17.95795902	19.10446722	9.019600494	9.570618604	8.705357551	3	27055515	27213152	+	TTC7A	protein_coding	GO:0006879|cellular iron ion homeostasis; GO:0030097|hemopoiesis; GO:0072659|protein localization to plasma membrane	GO:0005737|cytoplasm; GO:0005886|plasma membrane	--	--	--	2650	NP_001026226.1	NP_001026226.1 tetratricopeptide repeat protein 7A [Gallus gallus]	sp|Q9ULT0|TTC7A_HUMAN	sp|Q9ULT0|TTC7A_HUMAN Tetratricopeptide repeat protein 7A OS=Homo sapiens GN=TTC7A PE=1 SV=3	_	_	_	_	_	PF13432.3|TPR_16|Tetratricopeptide repeat|ENSGALT00000068038|m.11316:740-801
ENSGALG00000010032	9.775315974	30.91444426	-1.660057327	2.16E-100	2.69E-98	down	yes	9.064320038	10.44049291	9.821134974	30.61175162	29.93007033	32.20151083	3	27415048	27479318	-	ENSGALG00000010032	protein_coding	GO:0016042|lipid catabolic process	GO:0016021|integral component of membrane; GO:0016324|apical plasma membrane	"GO:0004622|lysophospholipase activity; GO:0004623|phospholipase A2 activity; GO:0102567|phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine); GO:0102568|phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)"	"ko:K14621|PLB1,PLB"	ko00564|Glycerophospholipid metabolism; ko00565|Ether lipid metabolism; ko00590|Arachidonic acid metabolism; ko00591|Linoleic acid metabolism; ko00592|alpha-Linolenic acid metabolism; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko04977|Vitamin digestion and absorption	3482	XP_010705095.1	"XP_010705095.1 PREDICTED: phospholipase B1, membrane-associated [Meleagris gallopavo]"	sp|Q06HQ7|PLB1_MONDO	"sp|Q06HQ7|PLB1_MONDO Phospholipase B1, membrane-associated OS=Monodelphis domestica GN=PLB1 PE=2 SV=1"	9031.ENSGALP00000016277	phospholipase B1	_	KOG3670	_	PF00657.19|Lipase_GDSL|GDSL-like Lipase/Acylhydrolase|ENSGALT00000016296|m.11322:419-691;PF00657.19|Lipase_GDSL|GDSL-like Lipase/Acylhydrolase|ENSGALT00000016296|m.11322:773-1045;PF13472.3|Lipase_GDSL_2|GDSL-like Lipase/Acylhydrolase family|ENSGALT00000016296|m.11322:421-642;PF13472.3|Lipase_GDSL_2|GDSL-like Lipase/Acylhydrolase family|ENSGALT00000016296|m.11322:775-1038
ENSGALG00000010050	0.184310662	0.596716161	-1.642656672	0.000282007	0.00064597	down	yes	0.209091623	0.168636776	0.175203588	0.621330539	0.686368275	0.482449669	3	28348991	28495437	+	LRFN2	protein_coding	GO:0007409|axonogenesis	GO:0005615|extracellular space; GO:0009986|cell surface; GO:0016021|integral component of membrane; GO:0030054|cell junction; GO:0031012|extracellular matrix; GO:0045211|postsynaptic membrane	--	"ko:K16355|LRFN2,SALM1"	--	2520	XP_004935432.1	XP_004935432.1 leucine-rich repeat and fibronectin type-III domain-containing protein 2 [Gallus gallus]	sp|Q460M5|LRFN2_RAT	sp|Q460M5|LRFN2_RAT Leucine-rich repeat and fibronectin type-III domain-containing protein 2 OS=Rattus norvegicus GN=Lrfn2 PE=1 SV=1	_	_	_	_	_	PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000016331|m.11341:54-111;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000016331|m.11341:100-146;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000016331|m.11341:124-184;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000016331|m.11341:173-214;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000016331|m.11341:289-375;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000016331|m.11341:287-362;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000016331|m.11341:65-198;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000016331|m.11341:295-370;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000016331|m.11341:412-485
ENSGALG00000010078	0.600956805	2.015818597	-1.729362703	2.47E-17	1.94E-16	down	yes	0.48719399	0.605705704	0.709970721	1.868426023	2.354089012	1.824940755	3	29410438	29492850	-	GLP1R	protein_coding	GO:0006950|response to stress; GO:0007166|cell surface receptor signaling pathway; GO:0007189|adenylate cyclase-activating G protein-coupled receptor signaling pathway; GO:0007204|positive regulation of cytosolic calcium ion concentration; GO:0007218|neuropeptide signaling pathway; GO:0007611|learning or memory; GO:0008016|regulation of heart contraction; GO:0019933|cAMP-mediated signaling; GO:0045777|positive regulation of blood pressure	GO:0005622|intracellular; GO:0005887|integral component of plasma membrane	GO:0004967|glucagon receptor activity; GO:0038023|signaling receptor activity; GO:0044508|glucagon-like peptide 1 receptor activity	ko:K04581|GLP1R	ko04024|cAMP signaling pathway; ko04080|Neuroactive ligand-receptor interaction; ko04911|Insulin secretion	4523	NP_001129023.1	NP_001129023.1 glucagon-like peptide 1 receptor precursor [Gallus gallus]	sp|O35659|GLP1R_MOUSE	sp|O35659|GLP1R_MOUSE Glucagon-like peptide 1 receptor OS=Mus musculus GN=Glp1r PE=1 SV=2	_	_	_	_	_	PF00002.21|7tm_2|7 transmembrane receptor (Secretin family)|ENSGALT00000077114|m.11367:138-394;PF02793.19|HRM|Hormone receptor domain|ENSGALT00000077114|m.11367:59-126;PF05462.8|Dicty_CAR|Slime mold cyclic AMP receptor|ENSGALT00000077114|m.11367:143-311
ENSGALG00000010110	3.983159295	1.388719372	1.513424084	2.10E-11	1.05E-10	up	yes	4.259673644	3.490631288	4.199172953	1.211799724	1.528958139	1.425400254	8	21085109	21088405	-	TMEM53	protein_coding	--	GO:0016021|integral component of membrane	--	--	--	1472	NP_001264509.1	NP_001264509.1 transmembrane protein 53 [Gallus gallus]	sp|Q5PPS7|TM53A_XENLA	sp|Q5PPS7|TM53A_XENLA Transmembrane protein 53-A OS=Xenopus laevis GN=tmem53-a PE=2 SV=1	9031.ENSGALP00000016422	transmembrane protein 53	_	KOG2521	_	PF05705.11|DUF829|Eukaryotic protein of unknown function (DUF829)|ENSGALT00000083555|m.7787:57-293
ENSGALG00000010116	0.056084738	0.425228513	-2.719384045	3.76E-22	4.00E-21	down	yes	0.045179926	0.080054406	0.043019881	0.422026295	0.433311022	0.420348223	3	29501011	29619293	-	DNAH8	protein_coding	GO:0003341|cilium movement; GO:0036158|outer dynein arm assembly	GO:0005737|cytoplasm; GO:0005874|microtubule; GO:0030286|dynein complex; GO:0036157|outer dynein arm; GO:0097228|sperm principal piece	"GO:0005524|ATP binding; GO:0008569|ATP-dependent microtubule motor activity, minus-end-directed; GO:0045503|dynein light chain binding; GO:0045505|dynein intermediate chain binding; GO:0051959|dynein light intermediate chain binding"	ko:K10408|DNAH	ko05016|Huntington's disease	13995	XP_025004702.1	"XP_025004702.1 dynein heavy chain 8, axonemal [Gallus gallus]"	sp|Q91XQ0|DYH8_MOUSE	"sp|Q91XQ0|DYH8_MOUSE Dynein heavy chain 8, axonemal OS=Mus musculus GN=Dnah8 PE=1 SV=2"	9031.ENSGALP00000016434	annotation not avaliable	COG5245	KOG3595	_	"PF03028.12|Dynein_heavy|Dynein heavy chain and region D6 of dynein motor|ENSGALT00000038200|m.11373:3975-4661;PF08385.9|DHC_N1|Dynein heavy chain, N-terminal region 1|ENSGALT00000038200|m.11373:329-882;PF08393.10|DHC_N2|Dynein heavy chain, N-terminal region 2|ENSGALT00000038200|m.11373:1445-1849;PF12774.4|AAA_6|Hydrolytic ATP binding site of dynein motor region D1|ENSGALT00000038200|m.11373:1985-2216;PF12781.4|AAA_9|ATP-binding dynein motor region D5|ENSGALT00000038200|m.11373:3612-3835;PF12780.4|AAA_8|P-loop containing dynein motor region D4|ENSGALT00000038200|m.11373:2965-3227;PF12775.4|AAA_7|P-loop containing dynein motor region D3|ENSGALT00000038200|m.11373:2604-2868;PF12777.4|MT|Microtubule-binding stalk of dynein motor|ENSGALT00000038200|m.11373:3241-3587;PF07728.11|AAA_5|AAA domain (dynein-related subfamily)|ENSGALT00000038200|m.11373:2302-2436;PF07728.11|AAA_5|AAA domain (dynein-related subfamily)|ENSGALT00000038200|m.11373:2629-2767"
ENSGALG00000010119	1.318618349	4.017442591	-1.59993728	4.69E-12	2.47E-11	down	yes	1.588244641	1.337604051	1.030006356	3.350369836	5.339232079	3.362725859	4	34029543	34062799	-	CDKL2	protein_coding	--	GO:0005634|nucleus; GO:0005737|cytoplasm	GO:0004693|cyclin-dependent protein serine/threonine kinase activity; GO:0005524|ATP binding	ko:K08824|CDKL	--	2455	XP_025006172.1	XP_025006172.1 cyclin-dependent kinase-like 2 isoform X9 [Gallus gallus]	sp|Q4R7T5|CDKL2_MACFA	sp|Q4R7T5|CDKL2_MACFA Cyclin-dependent kinase-like 2 OS=Macaca fascicularis GN=CDKL2 PE=2 SV=1	9031.ENSGALP00000016441	cyclin-dependent kinase-like 2 (CDC2-related kinase)	COG0515	KOG0593	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000016460|m.149:4-287;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000016460|m.149:9-283;PF14531.3|Kinase-like|Kinase-like|ENSGALT00000016460|m.149:102-192
ENSGALG00000010145	5.17271867	1.938338069	1.411465052	3.40E-30	5.39E-29	up	yes	5.705338239	4.824373098	4.988444673	1.805347204	2.157618212	1.85204879	3	30006735	30187312	+	MDGA1	protein_coding	GO:0001764|neuron migration	GO:0046658|anchored component of plasma membrane	--	--	--	4039	XP_015139196.1	XP_015139196.1 MAM domain-containing glycosylphosphatidylinositol anchor protein 1 isoform X1 [Gallus gallus]	sp|Q0WYX8|MDGA1_CHICK	sp|Q0WYX8|MDGA1_CHICK MAM domain-containing glycosylphosphatidylinositol anchor protein 1 OS=Gallus gallus GN=MDGA1 PE=1 SV=1	_	_	_	_	_	"PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000098708|m.11379:67-132;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000098708|m.11379:152-237;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000098708|m.11379:259-332;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000098708|m.11379:362-438;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000098708|m.11379:459-534;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000098708|m.11379:557-633;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000098708|m.11379:68-135;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000098708|m.11379:169-238;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000098708|m.11379:268-344;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000098708|m.11379:364-438;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000098708|m.11379:469-535;PF00629.20|MAM|MAM domain, meprin/A5/mu|ENSGALT00000098708|m.11379:767-931;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000098708|m.11379:68-137;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000098708|m.11379:167-239;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000098708|m.11379:266-341;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000098708|m.11379:362-441;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000098708|m.11379:467-535;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000098708|m.11379:152-241;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000098708|m.11379:265-344;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000098708|m.11379:460-537"
ENSGALG00000010152	8.652393477	1.354344558	2.666557671	3.58E-36	7.49E-35	up	yes	8.939511527	9.883705928	7.133962976	1.22760896	1.515233201	1.320191514	1	36249788	36266933	-	TSPAN8	protein_coding	GO:0007166|cell surface receptor signaling pathway; GO:0007283|spermatogenesis; GO:0010468|regulation of gene expression; GO:0030195|negative regulation of blood coagulation	GO:0005887|integral component of plasma membrane; GO:0009986|cell surface; GO:0070062|extracellular exosome	GO:0005178|integrin binding	ko:K17349|TSPAN8	--	1114	NP_001186579.1	NP_001186579.1 tetraspanin-8 [Gallus gallus]	sp|Q8R3G9|TSN8_MOUSE	sp|Q8R3G9|TSN8_MOUSE Tetraspanin-8 OS=Mus musculus GN=Tspan8 PE=1 SV=1	9031.ENSGALP00000016483	tetraspanin 8	_	KOG3882	_	PF00335.17|Tetraspannin|Tetraspanin family|ENSGALT00000016502|m.897:8-237
ENSGALG00000010189	37.11236661	81.65954223	-1.137509454	9.85E-79	7.78E-77	down	yes	36.9664063	37.58502947	36.78566406	81.80754856	85.99344709	77.17763105	5	37829239	37858026	+	ENSGALG00000010189	protein_coding	GO:0006888|endoplasmic reticulum to Golgi vesicle-mediated transport; GO:0035459|vesicle cargo loading; GO:0042953|lipoprotein transport	GO:0005789|endoplasmic reticulum membrane; GO:0016021|integral component of membrane; GO:0070971|endoplasmic reticulum exit site	--	--	--	4214	XP_004941833.1	XP_004941833.1 endoplasmic reticulum export factor CTAGE5 isoform X1 [Gallus gallus]	sp|Q96PC5|MIA2_HUMAN	sp|Q96PC5|MIA2_HUMAN Melanoma inhibitory activity protein 2 OS=Homo sapiens GN=MIA2 PE=1 SV=4	9031.ENSGALP00000016543	"CTAGE family, member 5"	_	_	NOG133684	PF07653.14|SH3_2|Variant SH3 domain|ENSGALT00000106900|m.3445:43-98
ENSGALG00000010218	4.006505556	9.402608139	-1.228653662	1.61E-10	7.49E-10	down	yes	3.051756627	3.965279561	5.002480481	10.57823373	7.623700472	10.00589022	9	22947045	22955401	-	ENSGALG00000010218	protein_coding	--	--	--	--	--	1364	XP_025009469.1	"XP_025009469.1 leucine-, glutamate- and lysine-rich protein 1 isoform X1 [Gallus gallus]"	sp|Q6ZMV7|LEKR1_HUMAN	"sp|Q6ZMV7|LEKR1_HUMAN Leucine-, glutamate- and lysine-rich protein 1 OS=Homo sapiens GN=LEKR1 PE=2 SV=2"	9031.ENSGALP00000016592	"leucine, glutamate and lysine rich 1"	_	KOG4674	_	_
ENSGALG00000010230	4.625763225	10.23134837	-1.143526886	5.29E-19	4.69E-18	down	yes	5.030175571	4.53639879	4.310715315	9.403694395	10.40464596	10.88570477	8	21400454	21458320	-	TESK2	protein_coding	GO:0006468|protein phosphorylation; GO:0007283|spermatogenesis; GO:0030036|actin cytoskeleton organization; GO:0035556|intracellular signal transduction; GO:0048041|focal adhesion assembly	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0016604|nuclear body	GO:0004672|protein kinase activity; GO:0004674|protein serine/threonine kinase activity; GO:0004712|protein serine/threonine/tyrosine kinase activity; GO:0004713|protein tyrosine kinase activity; GO:0005524|ATP binding; GO:0046872|metal ion binding	ko:K08842|TESK2	--	2095	XP_003641736.2	XP_003641736.2 dual specificity testis-specific protein kinase 2 isoform X1 [Gallus gallus]	sp|Q96S53|TESK2_HUMAN	sp|Q96S53|TESK2_HUMAN Dual specificity testis-specific protein kinase 2 OS=Homo sapiens GN=TESK2 PE=1 SV=1	_	_	_	_	_	PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000016630|m.7856:62-306;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000016630|m.7856:62-304
ENSGALG00000010303	28.93854405	66.76933189	-1.205910869	1.99E-53	8.14E-52	down	yes	26.52558244	29.54688128	30.74316843	71.1069724	65.44864427	63.752379	3	30966869	30977586	+	ENSGALG00000010303	protein_coding	GO:0001889|liver development; GO:0006725|cellular aromatic compound metabolic process; GO:0009636|response to toxic substance; GO:0014070|response to organic cyclic compound; GO:0019439|aromatic compound catabolic process; GO:0034312|diol biosynthetic process; GO:0071310|cellular response to organic substance; GO:0071385|cellular response to glucocorticoid stimulus; GO:0097176|epoxide metabolic process	GO:0005789|endoplasmic reticulum membrane; GO:0005886|plasma membrane; GO:0016020|membrane; GO:0016021|integral component of membrane; GO:0031090|organelle membrane; GO:0043231|intracellular membrane-bounded organelle	GO:0004301|epoxide hydrolase activity; GO:0019899|enzyme binding; GO:0033961|cis-stilbene-oxide hydrolase activity	ko:K01253|EPHX1	ko00980|Metabolism of xenobiotics by cytochrome P450; ko04976|Bile secretion; ko05204|Chemical carcinogenesis	1756	XP_019468323.1	XP_019468323.1 PREDICTED: epoxide hydrolase 1-like isoform X1 [Meleagris gallopavo]	sp|P07687|HYEP_RAT	sp|P07687|HYEP_RAT Epoxide hydrolase 1 OS=Rattus norvegicus GN=Ephx1 PE=1 SV=1	9031.ENSGALP00000016743	similar to Ephx1 protein	COG0596	KOG2565	_	PF06441.9|EHN|Epoxide hydrolase N terminus|ENSGALT00000016762|m.11446:76-185;PF00561.17|Abhydrolase_1|alpha/beta hydrolase fold|ENSGALT00000016762|m.11446:171-278
ENSGALG00000010322	19.09604091	39.98817388	-1.065905276	1.21E-33	2.29E-32	down	yes	20.76894066	18.4950007	18.02418137	42.70734353	36.70037248	40.55680563	5	38459491	38481098	+	JDP2	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0031065|positive regulation of histone deacetylation; GO:0045599|negative regulation of fat cell differentiation"	GO:0005634|nucleus	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0001227|DNA-binding transcription repressor activity, RNA polymerase II-specific; GO:0003682|chromatin binding; GO:0046982|protein heterodimerization activity"	ko:K09033|JDP2	--	1644	XP_019407786.1	XP_019407786.1 PREDICTED: jun dimerization protein 2 isoform X1 [Crocodylus porosus]	sp|Q8WYK2|JDP2_HUMAN	sp|Q8WYK2|JDP2_HUMAN Jun dimerization protein 2 OS=Homo sapiens GN=JDP2 PE=1 SV=1	9031.ENSGALP00000016784	Jun dimerization protein 2	_	KOG1414	_	PF00170.18|bZIP_1|bZIP transcription factor|ENSGALT00000097372|m.3564:96-154;PF07716.12|bZIP_2|Basic region leucine zipper|ENSGALT00000097372|m.3564:97-150;PF03131.14|bZIP_Maf|bZIP Maf transcription factor|ENSGALT00000097372|m.3564:100-156
ENSGALG00000010323	1.631837308	5.639181134	-1.782730584	2.57E-23	2.92E-22	down	yes	1.831452158	1.20390966	1.860150106	5.511179289	5.303446991	6.102917122	5	38487611	38497586	+	BATF	protein_coding	"GO:0001816|cytokine production; GO:0002320|lymphoid progenitor cell differentiation; GO:0006974|cellular response to DNA damage stimulus; GO:0030330|DNA damage response, signal transduction by p53 class mediator; GO:0042832|defense response to protozoan; GO:0043011|myeloid dendritic cell differentiation; GO:0045064|T-helper 2 cell differentiation; GO:0045190|isotype switching; GO:0060218|hematopoietic stem cell differentiation; GO:0072539|T-helper 17 cell differentiation; GO:0072540|T-helper 17 cell lineage commitment"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003700|DNA-binding transcription factor activity; GO:0043565|sequence-specific DNA binding"	ko:K09034|BATF	--	1898	XP_021257139.1	XP_021257139.1 basic leucine zipper transcriptional factor ATF-like isoform X2 [Numida meleagris]	sp|E1BD44|BATF_BOVIN	sp|E1BD44|BATF_BOVIN Basic leucine zipper transcriptional factor ATF-like OS=Bos taurus GN=BATF PE=3 SV=1	9031.ENSGALP00000016785	"basic leucine zipper transcription factor, ATF-like"	_	KOG1414	_	PF00170.18|bZIP_1|bZIP transcription factor|ENSGALT00000055740|m.3568:149-203;PF07716.12|bZIP_2|Basic region leucine zipper|ENSGALT00000055740|m.3568:148-200;PF03131.14|bZIP_Maf|bZIP Maf transcription factor|ENSGALT00000055740|m.3568:144-202
ENSGALG00000010371	9.933964504	34.21401588	-1.783116005	2.65E-112	4.50E-110	down	yes	10.61044451	9.746549192	9.444899812	32.7244283	35.22384811	34.69377124	4	35094094	35205619	-	FAM13A	protein_coding	GO:0007165|signal transduction; GO:0051056|regulation of small GTPase mediated signal transduction	GO:0005829|cytosol	GO:0005096|GTPase activator activity	--	--	2952	XP_025006028.1	XP_025006028.1 protein FAM13A isoform X5 [Gallus gallus]	sp|O94988|FA13A_HUMAN	sp|O94988|FA13A_HUMAN Protein FAM13A OS=Homo sapiens GN=FAM13A PE=1 SV=2	9031.ENSGALP00000016878	"family with sequence similarity 13, member A1"	_	KOG4270	NOG119761	PF00620.24|RhoGAP|RhoGAP domain|ENSGALT00000016897|m.242:39-186
ENSGALG00000010397	0.387276481	1.027108236	-1.384351174	6.95E-05	0.000174244	down	yes	0.549655246	0.222349078	0.389825119	0.869783539	1.019468385	1.192072784	4	36748697	37032793	+	GRID2	protein_coding	"GO:0006810|transport; GO:0007157|heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; GO:0007215|glutamate receptor signaling pathway; GO:0010975|regulation of neuron projection development; GO:0021707|cerebellar granule cell differentiation; GO:0034613|cellular protein localization; GO:0035249|synaptic transmission, glutamatergic; GO:0043523|regulation of neuron apoptotic process; GO:0051965|positive regulation of synapse assembly; GO:0060079|excitatory postsynaptic potential; GO:0060134|prepulse inhibition; GO:1900454|positive regulation of long-term synaptic depression; GO:1904861|excitatory synapse assembly"	GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0008328|ionotropic glutamate receptor complex; GO:0030054|cell junction; GO:0043197|dendritic spine; GO:0045202|synapse; GO:0045211|postsynaptic membrane	GO:0004970|ionotropic glutamate receptor activity; GO:0005234|extracellularly glutamate-gated ion channel activity; GO:0008066|glutamate receptor activity; GO:0030165|PDZ domain binding; GO:0097110|scaffold protein binding	ko:K05207|GRID2	ko04080|Neuroactive ligand-receptor interaction; ko04730|Long-term depression	2780	XP_420483.3	"XP_420483.3 glutamate receptor ionotropic, delta-2 isoform X2 [Gallus gallus]"	sp|O43424|GRID2_HUMAN	"sp|O43424|GRID2_HUMAN Glutamate receptor ionotropic, delta-2 OS=Homo sapiens GN=GRID2 PE=1 SV=2"	9031.ENSGALP00000016913	"glutamate receptor, ionotropic, delta 2"	_	KOG1052	_	"PF00060.23|Lig_chan|Ligand-gated ion channel|ENSGALT00000016932|m.259:485-760;PF01094.25|ANF_receptor|Receptor family ligand binding region|ENSGALT00000016932|m.259:2-322;PF10613.6|Lig_chan-Glu_bd|Ligated ion channel L-glutamate- and glycine-binding site|ENSGALT00000016932|m.259:361-470;PF00497.17|SBP_bac_3|Bacterial extracellular solute-binding proteins, family 3|ENSGALT00000016932|m.259:368-723"
ENSGALG00000010417	0.17658048	0.585846578	-1.675142841	0.000472631	0.001047084	down	yes	0.265001286	0.113341184	0.15139897	0.697758276	0.550236961	0.509544495	8	21968378	21979987	-	VDHAP	protein_coding	--	GO:0005739|mitochondrion; GO:0005743|mitochondrial inner membrane	GO:0004040|amidase activity	ko:K15528|FAAH	ko04723|Retrograde endocannabinoid signaling	2045	Q90578.3	Q90578.3 RecName: Full=Vitamin D3 hydroxylase-associated protein; Short=VDHAP	sp|Q90578|VDHAP_CHICK	sp|Q90578|VDHAP_CHICK Vitamin D3 hydroxylase-associated protein OS=Gallus gallus PE=1 SV=3	9031.ENSGALP00000016930	Vitamin D3 hydroxylase-associated protein (VDHAP); May have a vitamin D3 hydroxylase regulat [...] 	COG0154	KOG1212	_	PF01425.18|Amidase|Amidase|ENSGALT00000016958|m.7908:101-442;PF01425.18|Amidase|Amidase|ENSGALT00000016958|m.7909:4-114
ENSGALG00000010427	7.143035766	3.441904803	1.051162977	1.31E-07	4.62E-07	up	yes	7.666965114	6.941894553	6.82024763	4.045223105	2.910152384	3.370338919	9	23998508	24002932	-	TM4SF4	protein_coding	GO:0042246|tissue regeneration	GO:0016021|integral component of membrane	--	--	--	1024	XP_001234023.1	XP_001234023.1 transmembrane 4 L6 family member 4 [Gallus gallus]	sp|P48230|T4S4_HUMAN	sp|P48230|T4S4_HUMAN Transmembrane 4 L6 family member 4 OS=Homo sapiens GN=TM4SF4 PE=1 SV=1	9031.ENSGALP00000016960	transmembrane 4 L six family member 4	_	_	NOG46575	PF05805.9|L6_membrane|L6 membrane protein|ENSGALT00000016979|m.9403:1-190
ENSGALG00000010461	0.438933988	1.278652599	-1.521288159	5.49E-06	1.59E-05	down	yes	0.581004405	0.308477642	0.427319916	1.017358855	1.141001967	1.677596973	6	35112704	35230061	-	EBF3	protein_coding	"GO:0007275|multicellular organism development; GO:0045893|positive regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II"	GO:0005634|nucleus	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0046872|metal ion binding"	"ko:K09103|EBF,COE"	--	2473	XP_002194626.1	XP_002194626.1 PREDICTED: transcription factor COE3 isoform X3 [Taeniopygia guttata]	sp|O08791|COE3_MOUSE	sp|O08791|COE3_MOUSE Transcription factor COE3 OS=Mus musculus GN=Ebf3 PE=1 SV=1	9544.ENSMMUP00000015017	early B-cell factor 3	_	KOG3836	_	PF16422.2|COE1_DBD|Transcription factor COE1 DNA-binding domain|ENSGALT00000080706|m.5508:17-247;PF16423.2|COE1_HLH|Transcription factor COE1 helix-loop-helix domain|ENSGALT00000080706|m.5508:348-391;PF01833.21|TIG|IPT/TIG domain|ENSGALT00000080706|m.5508:263-345
ENSGALG00000010470	0.154814458	0.894555723	-2.456366571	1.16E-07	4.11E-07	down	yes	0.1230621	0.060152826	0.28122845	0.987511166	0.932853372	0.763302632	6	35538901	35604326	-	TCERG1L	protein_coding	--	--	--	--	--	2569	XP_421827.4	XP_421827.4 transcription elongation regulator 1-like protein [Gallus gallus]	sp|Q5VWI1|TCRGL_HUMAN	sp|Q5VWI1|TCRGL_HUMAN Transcription elongation regulator 1-like protein OS=Homo sapiens GN=TCERG1L PE=2 SV=2	9031.ENSGALP00000017032	transcription elongation regulator 1-like	_	KOG0155	_	PF01846.16|FF|FF domain|ENSGALT00000017051|m.5513:445-491;PF01846.16|FF|FF domain|ENSGALT00000017051|m.5513:510-558
ENSGALG00000010486	0.108224755	1.057994081	-3.1752996	1.26E-13	7.58E-13	down	yes	0.153060535	0.084168088	0.087445641	1.079502054	1.104761598	0.989718592	6	35793460	35816831	+	JAKMIP3	protein_coding	--	GO:0005794|Golgi apparatus	GO:0008017|microtubule binding; GO:0019900|kinase binding	--	--	2669	XP_015144499.1	XP_015144499.1 janus kinase and microtubule-interacting protein 3 isoform X5 [Gallus gallus]	sp|Q5VZ66|JKIP3_HUMAN	sp|Q5VZ66|JKIP3_HUMAN Janus kinase and microtubule-interacting protein 3 OS=Homo sapiens GN=JAKMIP3 PE=2 SV=2	9031.ENSGALP00000017056	chromosome 10 open reading frame 39	_	_	NOG127074	PF16034.2|JAKMIP_CC3|JAKMIP CC3 domain|ENSGALT00000093513|m.5517:423-619
ENSGALG00000010579	8.980356674	21.41845182	-1.253077363	2.75E-42	7.67E-41	down	yes	8.693841116	9.886436611	8.360792296	20.33749414	21.95045414	21.96740718	5	41075417	41130702	-	STON2	protein_coding	GO:0002244|hematopoietic progenitor cell differentiation; GO:0030100|regulation of endocytosis; GO:0048488|synaptic vesicle endocytosis	GO:0005730|nucleolus; GO:0005829|cytosol; GO:0008021|synaptic vesicle; GO:0016020|membrane; GO:0030054|cell junction; GO:0030136|clathrin-coated vesicle; GO:0043005|neuron projection	--	ko:K20067|STON1_2	--	2794	XP_421302.2	XP_421302.2 stonin-2 [Gallus gallus]	sp|D4AB66|STON2_RAT	sp|D4AB66|STON2_RAT Stonin-2 OS=Rattus norvegicus GN=Ston2 PE=1 SV=1	9031.ENSGALP00000017195	stonin 2	_	KOG2677	_	PF12016.5|Stonin2_N|Stonin 2|ENSGALT00000017215|m.3667:1-327;PF00928.18|Adap_comp_sub|Adaptor complexes medium subunit family|ENSGALT00000017215|m.3667:549-863
ENSGALG00000010592	10.92820031	24.84530085	-1.184178178	4.38E-07	1.46E-06	down	yes	13.70586871	11.25457603	7.824156191	26.32212186	23.59772709	24.6160536	4	38804855	38872224	-	TET2	protein_coding	GO:0006211|5-methylcytosine catabolic process; GO:0006493|protein O-linked glycosylation; GO:0007049|cell cycle; GO:0014070|response to organic cyclic compound; GO:0030099|myeloid cell differentiation; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0080111|DNA demethylation; GO:0080182|histone H3-K4 trimethylation	--	GO:0003677|DNA binding; GO:0008198|ferrous iron binding; GO:0008270|zinc ion binding; GO:0070579|methylcytosine dioxygenase activity	--	--	6291	XP_015131710.1	XP_015131710.1 methylcytosine dioxygenase TET2 isoform X2 [Gallus gallus]	sp|Q6N021|TET2_HUMAN	sp|Q6N021|TET2_HUMAN Methylcytosine dioxygenase TET2 OS=Homo sapiens GN=TET2 PE=1 SV=3	_	_	_	_	_	PF12851.4|Tet_JBP|Oxygenase domain of the 2OGFeDO superfamily|ENSGALT00000108375|m.324:1404-1999
ENSGALG00000010628	39.40644098	101.0701379	-1.358630115	5.46E-106	7.76E-104	down	yes	39.15847852	39.86602032	39.19482409	94.49377268	106.6003858	102.1162552	4	39432686	39469690	+	ACSL1	protein_coding	GO:0001676|long-chain fatty acid metabolic process; GO:0006641|triglyceride metabolic process; GO:0007584|response to nutrient; GO:0008610|lipid biosynthetic process; GO:0014070|response to organic cyclic compound; GO:0019216|regulation of lipid metabolic process; GO:0033211|adiponectin-activated signaling pathway; GO:0034201|response to oleic acid; GO:0035338|long-chain fatty-acyl-CoA biosynthetic process; GO:0036109|alpha-linolenic acid metabolic process; GO:0042178|xenobiotic catabolic process; GO:0042493|response to drug; GO:0043651|linoleic acid metabolic process; GO:0044539|long-chain fatty acid import into cell; GO:0071902|positive regulation of protein serine/threonine kinase activity	GO:0005739|mitochondrion; GO:0005741|mitochondrial outer membrane; GO:0005778|peroxisomal membrane; GO:0005789|endoplasmic reticulum membrane; GO:0005886|plasma membrane; GO:0016020|membrane; GO:0016021|integral component of membrane	GO:0004467|long-chain fatty acid-CoA ligase activity; GO:0005524|ATP binding; GO:0102391|decanoate-CoA ligase activity	"ko:K01897|ACSL,fadD"	ko00061|Fatty acid biosynthesis; ko00071|Fatty acid degradation; ko01100|Metabolic pathways; ko01212|Fatty acid metabolism; ko02024|Quorum sensing; ko03320|PPAR signaling pathway; ko04146|Peroxisome; ko04216|Ferroptosis; ko04920|Adipocytokine signaling pathway	3862	NP_001012596.1	NP_001012596.1 long-chain-fatty-acid--CoA ligase 1 [Gallus gallus]	sp|P33121|ACSL1_HUMAN	sp|P33121|ACSL1_HUMAN Long-chain-fatty-acid--CoA ligase 1 OS=Homo sapiens GN=ACSL1 PE=1 SV=1	9031.ENSGALP00000017274	acyl-CoA synthetase long-chain family member 1 	COG1022	KOG1256	_	PF00501.25|AMP-binding|AMP-binding enzyme|ENSGALT00000088260|m.346:117-563
ENSGALG00000010635	1.867405956	0.399935532	2.195271692	1.86E-16	1.38E-15	up	yes	1.548702686	2.283923833	1.769591351	0.377328153	0.508101777	0.314376667	3	33929665	33952049	+	ENSGALG00000010635	protein_coding	GO:0007005|mitochondrion organization; GO:0007018|microtubule-based movement; GO:0072384|organelle transport along microtubule	GO:0005622|intracellular; GO:0005871|kinesin complex; GO:0031966|mitochondrial membrane	GO:0003777|microtubule motor activity; GO:0005524|ATP binding; GO:0008017|microtubule binding; GO:0016887|ATPase activity	--	--	2994	XP_025005037.1	XP_025005037.1 kinesin-like protein KIF28P isoform X2 [Gallus gallus]	sp|D3YXS5|KIF28_MOUSE	sp|D3YXS5|KIF28_MOUSE Kinesin-like protein KIF28P OS=Mus musculus GN=Kif28p PE=3 SV=1	_	_	_	_	_	PF00225.20|Kinesin|Kinesin motor domain|ENSGALT00000017305|m.11555:12-344;PF16796.2|Microtub_bd|Microtubule binding|ENSGALT00000017305|m.11555:80-158;PF00498.23|FHA|FHA domain|ENSGALT00000017305|m.11555:439-502;PF12423.5|KIF1B|Kinesin protein 1B|ENSGALT00000017305|m.11555:630-667
ENSGALG00000010642	10.87273452	23.29178147	-1.098399147	2.86E-39	6.90E-38	down	yes	11.01032998	11.43541308	10.17246049	23.85335444	24.05336105	21.96862893	4	39520122	39561578	+	IRF2	protein_coding	GO:0008283|cell population proliferation; GO:0051607|defense response to virus	GO:0005654|nucleoplasm; GO:0005829|cytosol; GO:0005925|focal adhesion	"GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific"	ko:K10153|IRF2	--	2275	XP_013035269.1	XP_013035269.1 PREDICTED: interferon regulatory factor 2 isoform X1 [Anser cygnoides domesticus]	sp|Q98925|IRF2_CHICK	sp|Q98925|IRF2_CHICK Interferon regulatory factor 2 OS=Gallus gallus GN=IRF2 PE=2 SV=1	_	_	_	_	_	PF00605.14|IRF|Interferon regulatory factor transcription factor|ENSGALT00000038252|m.359:7-111
ENSGALG00000010645	0.627977942	1.3155493	-1.05501188	0.004786339	0.008998495	down	yes	0.449759789	0.393180473	1.040993563	0.722252792	1.511965997	1.71242911	4	39577144	39603215	+	ENPP6	protein_coding	GO:0006629|lipid metabolic process; GO:0016042|lipid catabolic process; GO:0019695|choline metabolic process	GO:0005576|extracellular region; GO:0005886|plasma membrane; GO:0031225|anchored component of membrane; GO:0070062|extracellular exosome	GO:0008081|phosphoric diester hydrolase activity; GO:0008889|glycerophosphodiester phosphodiesterase activity; GO:0047390|glycerophosphocholine cholinephosphodiesterase activity	ko:K08743|ENPP6	ko00565|Ether lipid metabolism	3019	XP_420512.1	XP_420512.1 ectonucleotide pyrophosphatase/phosphodiesterase family member 6 [Gallus gallus]	sp|Q8BGN3|ENPP6_MOUSE	sp|Q8BGN3|ENPP6_MOUSE Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 OS=Mus musculus GN=Enpp6 PE=1 SV=1	9031.ENSGALP00000017297	ectonucleotide pyrophosphatase/phosphodiesterase 6	COG1524	KOG2645	_	PF01663.19|Phosphodiest|Type I phosphodiesterase / nucleotide pyrophosphatase|ENSGALT00000098782|m.362:22-353
ENSGALG00000010664	0.061868699	0.171382435	-1.335599281	0.004740093	0.008921268	down	yes	0.06284907	0.074881613	0.047875413	0.162528876	0.211280909	0.140337519	3	34279395	34717416	-	KIF26B	protein_coding	GO:0022409|positive regulation of cell-cell adhesion; GO:0030010|establishment of cell polarity; GO:0072092|ureteric bud invasion	GO:0005737|cytoplasm; GO:0005871|kinesin complex; GO:0005874|microtubule	GO:0003777|microtubule motor activity; GO:0005524|ATP binding; GO:0008017|microtubule binding	ko:K10404|KIF26	--	6360	XP_003641032.1	XP_003641032.1 kinesin-like protein KIF26B isoform X1 [Gallus gallus]	sp|Q2KJY2|KI26B_HUMAN	sp|Q2KJY2|KI26B_HUMAN Kinesin-like protein KIF26B OS=Homo sapiens GN=KIF26B PE=2 SV=1	9031.ENSGALP00000017330	annotation not avaliable	COG5059	KOG4280	_	PF00225.20|Kinesin|Kinesin motor domain|ENSGALT00000017350|m.11570:495-798;PF16796.2|Microtub_bd|Microtubule binding|ENSGALT00000017350|m.11570:449-611
ENSGALG00000010711	0.941608191	0.421642626	1.140530347	0.012680406	0.021969794	up	yes	1.055277337	0.827090968	0.942456267	0.588567183	0.446141663	0.230219032	2	25087512	25222398	+	NXPH1	protein_coding	--	GO:0005576|extracellular region	--	ko:K16656|NXPH1	--	1248	XP_019353662.1	XP_019353662.1 PREDICTED: neurexophilin-1 isoform X1 [Alligator mississippiensis]	sp|Q5R530|NXPH1_PONAB	sp|Q5R530|NXPH1_PONAB Neurexophilin-1 OS=Pongo abelii GN=NXPH1 PE=2 SV=1	59729.ENSTGUP00000001742	Neurexophilin-1 Precursor [Taeniopygia guttata]	_	_	NOG46541	PF06312.9|Neurexophilin|Neurexophilin|ENSGALT00000071259|m.91:66-271
ENSGALG00000010713	3.982262461	8.566922906	-1.103253583	1.09E-23	1.27E-22	down	yes	4.331183628	3.975009717	3.640594038	8.673909153	8.795201039	8.231658525	3	35221764	35325431	-	ENSGALG00000010713	protein_coding	GO:0001764|neuron migration; GO:0007098|centrosome cycle; GO:0030010|establishment of cell polarity; GO:0031023|microtubule organizing center organization; GO:0035148|tube formation	GO:0005737|cytoplasm; GO:0005813|centrosome; GO:0005814|centriole; GO:0005911|cell-cell junction; GO:0034451|centriolar satellite	--	ko:K16488|SDCCAG8	--	3196	XP_419545.3	XP_419545.3 serologically defined colon cancer antigen 8 isoform X2 [Gallus gallus]	sp|Q80UF4|SDCG8_MOUSE	sp|Q80UF4|SDCG8_MOUSE Serologically defined colon cancer antigen 8 homolog OS=Mus musculus GN=Sdccag8 PE=1 SV=1	9031.ENSGALP00000017409	serologically defined colon cancer antigen 8	_	_	NOG69678	PF15964.2|CCCAP|Centrosomal colon cancer autoantigen protein family|ENSGALT00000017430|m.11592:6-713
ENSGALG00000010738	0.295092277	0.851965611	-1.498384653	0.004619634	0.008710836	down	yes	0.436447274	0.116364917	0.33246464	0.895466462	0.863066509	0.797363862	5	44630721	44653557	-	TC2N	protein_coding	GO:0010468|regulation of gene expression; GO:0030193|regulation of blood coagulation	GO:0005634|nucleus; GO:0005886|plasma membrane	--	ko:K17287|TC2N	--	1328	XP_004941929.2	XP_004941929.2 tandem C2 domains nuclear protein isoform X1 [Gallus gallus]	sp|Q8N9U0|TAC2N_HUMAN	sp|Q8N9U0|TAC2N_HUMAN Tandem C2 domains nuclear protein OS=Homo sapiens GN=TC2N PE=1 SV=2	9031.ENSGALP00000017454	"tandem C2 domains, nuclear"	_	KOG1028	_	PF00168.27|C2|C2 domain|ENSGALT00000070131|m.3747:241-340
ENSGALG00000010768	4.042419284	1.333620395	1.592657851	1.37E-12	7.58E-12	up	yes	4.34312243	3.685069996	4.099065426	0.934986444	1.652870592	1.413004148	3	35970274	35972202	-	PIGM	protein_coding	GO:0006506|GPI anchor biosynthetic process	GO:0005789|endoplasmic reticulum membrane; GO:0016021|integral component of membrane	"GO:0016758|transferase activity, transferring hexosyl groups"	ko:K05284|PIGM	ko00563|Glycosylphosphatidylinositol (GPI)-anchor biosynthesis; ko01100|Metabolic pathways	1929	NP_001026693.2	NP_001026693.2 GPI mannosyltransferase 1 [Gallus gallus]	sp|Q5F380|PIGM_CHICK	sp|Q5F380|PIGM_CHICK GPI mannosyltransferase 1 OS=Gallus gallus GN=PIGM PE=2 SV=2	9031.ENSGALP00000037081	GPI mannosyltransferase 1 (EC 2.4.1.-)(GPI mannosyltransferase I)(GPI-MT-I)(Phosphatidylinos [...] 	_	KOG3893	_	PF05007.10|Mannosyl_trans|Mannosyltransferase (PIG-M)|ENSGALT00000017511|m.11620:136-407;PF06728.10|PIG-U|GPI transamidase subunit PIG-U|ENSGALT00000017511|m.11620:46-363;PF09594.7|DUF2029|Protein of unknown function (DUF2029)|ENSGALT00000017511|m.11620:69-255
ENSGALG00000010798	93.66292771	18.85447605	2.311960126	2.06E-296	4.98E-293	up	yes	89.47016719	96.48565824	95.03295771	17.76681369	19.69643102	19.10018343	8	25608221	25616427	-	DHCR24	protein_coding	GO:0006695|cholesterol biosynthetic process; GO:0006915|apoptotic process; GO:0006979|response to oxidative stress; GO:0007050|cell cycle arrest; GO:0007265|Ras protein signal transduction; GO:0008104|protein localization; GO:0008285|negative regulation of cell population proliferation; GO:0009725|response to hormone; GO:0009888|tissue development; GO:0030539|male genitalia development; GO:0031639|plasminogen activation; GO:0033489|cholesterol biosynthetic process via desmosterol; GO:0033490|cholesterol biosynthetic process via lathosterol; GO:0042987|amyloid precursor protein catabolic process; GO:0043066|negative regulation of apoptotic process; GO:0043154|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0043588|skin development; GO:0055114|oxidation-reduction process; GO:0061024|membrane organization; GO:1901214|regulation of neuron death	GO:0000139|Golgi membrane; GO:0005634|nucleus; GO:0005783|endoplasmic reticulum; GO:0005789|endoplasmic reticulum membrane; GO:0005829|cytosol; GO:0005856|cytoskeleton; GO:0016020|membrane; GO:0016021|integral component of membrane	"GO:0000246|delta24(24-1) sterol reductase activity; GO:0016614|oxidoreductase activity, acting on CH-OH group of donors; GO:0016628|oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; GO:0019899|enzyme binding; GO:0042605|peptide antigen binding; GO:0050614|delta24-sterol reductase activity; GO:0050660|flavin adenine dinucleotide binding"	"ko:K09828|DHCR24,DWF1"	ko00100|Steroid biosynthesis; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites	3775	NP_001026459.1	NP_001026459.1 delta(24)-sterol reductase [Gallus gallus]	sp|Q15392|DHC24_HUMAN	sp|Q15392|DHC24_HUMAN Delta(24)-sterol reductase OS=Homo sapiens GN=DHCR24 PE=1 SV=2	9031.ENSGALP00000017539	24-dehydrocholesterol reductase 	COG0277	KOG1262	_	PF01565.20|FAD_binding_4|FAD binding domain|ENSGALT00000017560|m.8046:150-241
ENSGALG00000010822	0.595419148	2.267667394	-1.911550876	9.06E-06	2.56E-05	down	yes	0.736080407	0.629643926	0.420533112	2.676461343	1.843741699	2.282799141	4	44348398	44355142	-	SPATA4	protein_coding	--	GO:0005737|cytoplasm	--	--	--	859	NP_001026309.1	NP_001026309.1 spermatogenesis-associated protein 4 precursor [Gallus gallus]	sp|Q8NEY3|SPAT4_HUMAN	sp|Q8NEY3|SPAT4_HUMAN Spermatogenesis-associated protein 4 OS=Homo sapiens GN=SPATA4 PE=1 SV=1	9031.ENSGALP00000031560	spermatogenesis associated 4 	_	_	NOG74411	PF06294.8|CH_2|CH-like domain in sperm protein|ENSGALT00000032196|m.459:18-112;PF11971.5|CAMSAP_CH|CAMSAP CH domain|ENSGALT00000032196|m.459:29-99
ENSGALG00000010847	0.93666688	5.858007213	-2.63194189	1.10E-36	2.39E-35	down	yes	0.66872717	0.946808109	1.194465361	6.687508135	5.462862477	5.423651028	4	44468359	44536888	-	VEGFC	protein_coding	GO:0001525|angiogenesis; GO:0001666|response to hypoxia; GO:0001938|positive regulation of endothelial cell proliferation; GO:0001954|positive regulation of cell-matrix adhesion; GO:0002052|positive regulation of neuroblast proliferation; GO:0002576|platelet degranulation; GO:0006929|substrate-dependent cell migration; GO:0007165|signal transduction; GO:0008284|positive regulation of cell population proliferation; GO:0008285|negative regulation of cell population proliferation; GO:0009887|animal organ morphogenesis; GO:0016331|morphogenesis of embryonic epithelium; GO:0030947|regulation of vascular endothelial growth factor receptor signaling pathway; GO:0031954|positive regulation of protein autophosphorylation; GO:0042493|response to drug; GO:0043536|positive regulation of blood vessel endothelial cell migration; GO:0045766|positive regulation of angiogenesis; GO:0045776|negative regulation of blood pressure; GO:0048010|vascular endothelial growth factor receptor signaling pathway; GO:0050714|positive regulation of protein secretion; GO:0050731|positive regulation of peptidyl-tyrosine phosphorylation; GO:0050930|induction of positive chemotaxis; GO:0051781|positive regulation of cell division; GO:0060754|positive regulation of mast cell chemotaxis; GO:1901492|positive regulation of lymphangiogenesis; GO:1990830|cellular response to leukemia inhibitory factor	GO:0005576|extracellular region; GO:0005615|extracellular space; GO:0016020|membrane; GO:0031093|platelet alpha granule lumen	GO:0008083|growth factor activity; GO:0042056|chemoattractant activity; GO:0043185|vascular endothelial growth factor receptor 3 binding	ko:K05449|VEGFC_D	ko04014|Ras signaling pathway; ko04015|Rap1 signaling pathway; ko04060|Cytokine-cytokine receptor interaction; ko04151|PI3K-Akt signaling pathway; ko04510|Focal adhesion; ko04933|AGE-RAGE signaling pathway in diabetic complications; ko05200|Pathways in cancer	2162	XP_420532.3	XP_420532.3 vascular endothelial growth factor C [Gallus gallus]	sp|P49767|VEGFC_HUMAN	sp|P49767|VEGFC_HUMAN Vascular endothelial growth factor C OS=Homo sapiens GN=VEGFC PE=1 SV=1	9031.ENSGALP00000017608	vascular endothelial growth factor C	_	_	NOG79308	PF00341.14|PDGF|PDGF/VEGF domain|ENSGALT00000017629|m.467:298-378;PF03128.11|CXCXC|CXCXC repeat|ENSGALT00000017629|m.467:450-462;PF03128.11|CXCXC|CXCXC repeat|ENSGALT00000017629|m.467:498-510
ENSGALG00000010853	0.160811201	0.346934548	-1.063256963	0.012539395	0.021750432	down	yes	0.155087827	0.189517549	0.137828229	0.398629368	0.368020012	0.274154266	8	26178921	26194902	-	C8B	protein_coding	"GO:0006955|immune response; GO:0006956|complement activation; GO:0006957|complement activation, alternative pathway; GO:0006958|complement activation, classical pathway; GO:0019835|cytolysis; GO:0030449|regulation of complement activation"	GO:0005576|extracellular region; GO:0005579|membrane attack complex; GO:0016020|membrane; GO:0070062|extracellular exosome; GO:1903561|extracellular vesicle	GO:0044877|protein-containing complex binding	ko:K03998|C8B	ko04610|Complement and coagulation cascades; ko05020|Prion diseases; ko05146|Amoebiasis; ko05322|Systemic lupus erythematosus	4077	NP_001308472.1	NP_001308472.1 complement component C8 beta chain precursor [Gallus gallus]	sp|P07358|CO8B_HUMAN	sp|P07358|CO8B_HUMAN Complement component C8 beta chain OS=Homo sapiens GN=C8B PE=1 SV=3	9031.ENSGALP00000017617	"complement component 8, beta polypeptide"	_	_	NOG145238	PF01823.16|MACPF|MAC/Perforin domain|ENSGALT00000017638|m.8064:272-489;PF00057.15|Ldl_recept_a|Low-density lipoprotein receptor domain class A|ENSGALT00000017638|m.8064:115-149;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000017638|m.8064:62-110;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000017638|m.8064:545-584
ENSGALG00000010854	2.326107055	4.892608075	-1.069443045	9.25E-13	5.18E-12	down	yes	2.178538372	2.423032327	2.376750465	5.34033524	4.54167513	4.795813855	2	29076224	29386193	+	ENSGALG00000010854	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006351|transcription, DNA-templated; GO:0007507|heart development; GO:0045892|negative regulation of transcription, DNA-templated; GO:0048742|regulation of skeletal muscle fiber development; GO:0051153|regulation of striated muscle cell differentiation"	GO:0035097|histone methyltransferase complex	GO:0003714|transcription corepressor activity; GO:0032041|NAD-dependent histone deacetylase activity (H3-K14 specific)	ko:K11409|HDAC9	ko05034|Alcoholism; ko05203|Viral carcinogenesis	2336	XP_015136911.1	XP_015136911.1 histone deacetylase 9 isoform X5 [Gallus gallus]	sp|Q5ZKH6|HDAC9_CHICK	sp|Q5ZKH6|HDAC9_CHICK Histone deacetylase 9 OS=Gallus gallus GN=hdac9 PE=2 SV=1	9031.ENSGALP00000017619	"Histone deacetylase 9 (EC 3.5.1.98); Devoided of intrinsic deacetylase activity, promotes th [...] "	COG0123	KOG1343	_	PF12203.5|HDAC4_Gln|Glutamine rich N terminal domain of histone deacetylase 4|ENSGALT00000067701|m.145:58-148
ENSGALG00000010857	2.025938108	4.238924417	-1.061403976	9.46E-09	3.73E-08	down	yes	1.433449659	2.44849874	2.195865924	3.57287103	4.747210602	4.396691618	8	26201306	26289893	-	DAB1	protein_coding	GO:0007399|nervous system development; GO:0030154|cell differentiation	--	--	ko:K20054|DAB1	--	3288	XP_015146405.1	XP_015146405.1 disabled homolog 1 isoform X2 [Gallus gallus]	sp|Q9BGX5|DAB1_MACFA	sp|Q9BGX5|DAB1_MACFA Disabled homolog 1 OS=Macaca fascicularis GN=DAB1 PE=2 SV=1	9031.ENSGALP00000032354	disabled homolog 1 	_	KOG3535	_	PF00640.20|PID|Phosphotyrosine interaction domain (PTB/PID)|ENSGALT00000032993|m.8068:64-167
ENSGALG00000010864	0.55769134	1.741147304	-1.625121807	0.000583539	0.001273647	down	yes	0.718012745	0.323967734	0.631093542	1.911329674	1.092197754	2.219914485	4	44723699	44731614	+	EREG	protein_coding	"GO:0000165|MAPK cascade; GO:0001525|angiogenesis; GO:0001550|ovarian cumulus expansion; GO:0001556|oocyte maturation; GO:0001819|positive regulation of cytokine production; GO:0007143|female meiotic nuclear division; GO:0007173|epidermal growth factor receptor signaling pathway; GO:0007267|cell-cell signaling; GO:0008284|positive regulation of cell population proliferation; GO:0008285|negative regulation of cell population proliferation; GO:0009299|mRNA transcription; GO:0009653|anatomical structure morphogenesis; GO:0009887|animal organ morphogenesis; GO:0014066|regulation of phosphatidylinositol 3-kinase signaling; GO:0019221|cytokine-mediated signaling pathway; GO:0030216|keratinocyte differentiation; GO:0030728|ovulation; GO:0038111|interleukin-7-mediated signaling pathway; GO:0038128|ERBB2 signaling pathway; GO:0042060|wound healing; GO:0042108|positive regulation of cytokine biosynthetic process; GO:0042327|positive regulation of phosphorylation; GO:0042700|luteinizing hormone signaling pathway; GO:0043434|response to peptide hormone; GO:0043616|keratinocyte proliferation; GO:0045089|positive regulation of innate immune response; GO:0045410|positive regulation of interleukin-6 biosynthetic process; GO:0045740|positive regulation of DNA replication; GO:0045741|positive regulation of epidermal growth factor-activated receptor activity; GO:0045840|positive regulation of mitotic nuclear division; GO:0045860|positive regulation of protein kinase activity; GO:0045892|negative regulation of transcription, DNA-templated; GO:0048015|phosphatidylinositol-mediated signaling; GO:0048146|positive regulation of fibroblast proliferation; GO:0048160|primary follicle stage; GO:0048661|positive regulation of smooth muscle cell proliferation; GO:0050680|negative regulation of epithelial cell proliferation; GO:0051151|negative regulation of smooth muscle cell differentiation; GO:0051781|positive regulation of cell division; GO:1901185|negative regulation of ERBB signaling pathway; GO:2000145|regulation of cell motility"	GO:0005576|extracellular region; GO:0005615|extracellular space; GO:0005622|intracellular; GO:0005887|integral component of plasma membrane	"GO:0004713|protein tyrosine kinase activity; GO:0005088|Ras guanyl-nucleotide exchange factor activity; GO:0005154|epidermal growth factor receptor binding; GO:0008083|growth factor activity; GO:0046934|phosphatidylinositol-4,5-bisphosphate 3-kinase activity"	ko:K09784|EREG	ko04012|ErbB signaling pathway	954	NP_001001203.1	NP_001001203.1 proepiregulin precursor [Gallus gallus]	sp|O14944|EREG_HUMAN	sp|O14944|EREG_HUMAN Proepiregulin OS=Homo sapiens GN=EREG PE=1 SV=1	9031.ENSGALP00000017642	epiregulin 	_	_	NOG40865	_
ENSGALG00000010865	0.067092749	0.585931684	-2.950479877	6.49E-05	0.000163742	down	yes	0.09985677	0	0.101421476	0.600975091	0.710873778	0.445946182	2	29771902	29788849	-	TMEM196	protein_coding	--	GO:0016021|integral component of membrane	--	--	--	1507	XP_004939398.1	XP_004939398.1 transmembrane protein 196 isoform X4 [Gallus gallus]	sp|Q5HYL7|TM196_HUMAN	sp|Q5HYL7|TM196_HUMAN Transmembrane protein 196 OS=Homo sapiens GN=TMEM196 PE=2 SV=2	9685.ENSFCAP00000005030	transmembrane protein 196	_	_	NOG39881	_
ENSGALG00000010866	1.804856893	14.34512988	-2.983638686	1.95E-51	7.37E-50	down	yes	2.582255607	1.437958522	1.39435655	17.32375788	12.70773442	13.00389733	4	44741719	44748186	+	AREG	protein_coding	GO:0007173|epidermal growth factor receptor signaling pathway; GO:0007186|G protein-coupled receptor signaling pathway; GO:0007417|central nervous system development; GO:0008284|positive regulation of cell population proliferation; GO:0014009|glial cell proliferation; GO:0014070|response to organic cyclic compound; GO:0031175|neuron projection development; GO:0032355|response to estradiol; GO:0042327|positive regulation of phosphorylation; GO:0042542|response to hydrogen peroxide; GO:0043434|response to peptide hormone; GO:0045668|negative regulation of osteoblast differentiation; GO:0045740|positive regulation of DNA replication; GO:0050731|positive regulation of peptidyl-tyrosine phosphorylation; GO:0051384|response to glucocorticoid; GO:0051591|response to cAMP; GO:0060598|dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis; GO:0060744|mammary gland branching involved in thelarche; GO:0060749|mammary gland alveolus development; GO:0060750|epithelial cell proliferation involved in mammary gland duct elongation	GO:0005615|extracellular space; GO:0005622|intracellular; GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0009986|cell surface; GO:0016021|integral component of membrane	GO:0005125|cytokine activity; GO:0005154|epidermal growth factor receptor binding; GO:0008083|growth factor activity	ko:K09782|AREG	ko04012|ErbB signaling pathway; ko04390|Hippo signaling pathway	1612	NP_001026708.1	NP_001026708.1 amphiregulin precursor [Gallus gallus]	sp|P24338|AREG_RAT	sp|P24338|AREG_RAT Amphiregulin OS=Rattus norvegicus GN=Areg PE=1 SV=1	9031.ENSGALP00000017644	amphiregulin 	_	_	NOG41450	_
ENSGALG00000010867	1.219794638	0.56717845	1.091328081	0.024457247	0.039875443	up	yes	1.36270058	0.999133249	1.297550084	0.405790406	0.830870611	0.464874334	8	26673217	26674144	-	TACSTD2	protein_coding	GO:0010633|negative regulation of epithelial cell migration; GO:0050678|regulation of epithelial cell proliferation; GO:0051497|negative regulation of stress fiber assembly; GO:0060675|ureteric bud morphogenesis; GO:0090191|negative regulation of branching involved in ureteric bud morphogenesis; GO:0098609|cell-cell adhesion; GO:1900025|negative regulation of substrate adhesion-dependent cell spreading; GO:1900028|negative regulation of ruffle assembly; GO:2000146|negative regulation of cell motility; GO:2000738|positive regulation of stem cell differentiation	GO:0005615|extracellular space; GO:0005634|nucleus; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0009925|basal plasma membrane; GO:0016020|membrane; GO:0016328|lateral plasma membrane; GO:0070062|extracellular exosome	--	ko:K17288|TACSTD2	--	928	NP_001264605.1	NP_001264605.1 tumor-associated calcium signal transducer 2 precursor [Gallus gallus]	sp|Q8BGV3|TACD2_MOUSE	sp|Q8BGV3|TACD2_MOUSE Tumor-associated calcium signal transducer 2 OS=Mus musculus GN=Tacstd2 PE=1 SV=1	9031.ENSGALP00000017645	tumor-associated calcium signal transducer 2	_	_	NOG46689	PF00086.15|Thyroglobulin_1|Thyroglobulin type-1 repeat|ENSGALT00000017666|m.8070:91-129
ENSGALG00000010870	42.21263273	129.5440628	-1.617465815	1.12E-77	8.62E-76	down	yes	48.46469613	37.68315675	40.49004531	134.6065746	132.8799761	121.1456377	8	26714120	26715827	-	JUN	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006351|transcription, DNA-templated; GO:0007265|Ras protein signal transduction; GO:0009314|response to radiation; GO:0009612|response to mechanical stimulus; GO:0010941|regulation of cell death; GO:0030307|positive regulation of cell growth; GO:0032870|cellular response to hormone stimulus; GO:0034097|response to cytokine; GO:0042127|regulation of cell population proliferation; GO:0042493|response to drug; GO:0043923|positive regulation by host of viral transcription; GO:0045597|positive regulation of cell differentiation; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0051591|response to cAMP; GO:0051726|regulation of cell cycle"	GO:0000790|nuclear chromatin; GO:0005634|nucleus; GO:0005667|transcription factor complex	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0003713|transcription coactivator activity; GO:0008134|transcription factor binding; GO:0044212|transcription regulatory region DNA binding"	ko:K04448|JUN	ko01522|Endocrine resistance; ko04010|MAPK signaling pathway; ko04012|ErbB signaling pathway; ko04013|MAPK signaling pathway - fly; ko04024|cAMP signaling pathway; ko04137|Mitophagy - animal; ko04210|Apoptosis; ko04214|Apoptosis - fly; ko04310|Wnt signaling pathway; ko04380|Osteoclast differentiation; ko04510|Focal adhesion; ko04530|Tight junction; ko04620|Toll-like receptor signaling pathway; ko04621|NOD-like receptor signaling pathway; ko04624|Toll and Imd signaling pathway; ko04657|IL-17 signaling pathway; ko04658|Th1 and Th2 cell differentiation; ko04659|Th17 cell differentiation; ko04660|T cell receptor signaling pathway; ko04662|B cell receptor signaling pathway; ko04668|TNF signaling pathway; ko04722|Neurotrophin signaling pathway; ko04912|GnRH signaling pathway; ko04915|Estrogen signaling pathway; ko04921|Oxytocin signaling pathway; ko04932|Non-alcoholic fatty liver disease (NAFLD); ko04933|AGE-RAGE signaling pathway in diabetic complications; ko05030|Cocaine addiction; ko05031|Amphetamine addiction; ko05120|Epithelial cell signaling in Helicobacter pylori infection; ko05132|Salmonella infection; ko05133|Pertussis; ko05140|Leishmaniasis; ko05142|Chagas disease (American trypanosomiasis); ko05161|Hepatitis B; ko05164|Influenza A; ko05166|HTLV-I infection; ko05168|Herpes simplex infection; ko05169|Epstein-Barr virus infection; ko05200|Pathways in cancer; ko05203|Viral carcinogenesis; ko05210|Colorectal cancer; ko05211|Renal cell carcinoma; ko05224|Breast cancer; ko05231|Choline metabolism in cancer; ko05321|Inflammatory bowel disease (IBD); ko05323|Rheumatoid arthritis; ko05418|Fluid shear stress and atherosclerosis	1708	XP_015726135.1	XP_015726135.1 PREDICTED: transcription factor AP-1 [Coturnix japonica]	sp|P18870|JUN_CHICK	sp|P18870|JUN_CHICK Transcription factor AP-1 OS=Gallus gallus GN=JUN PE=1 SV=2	9031.ENSGALP00000037247	Transcription factor AP-1 (Proto-oncogene c-jun); Transcription factor that recognizes and b [...] 	_	KOG0837	_	PF03957.10|Jun|Jun-like transcription factor|ENSGALT00000038039|m.8076:5-224;PF00170.18|bZIP_1|bZIP transcription factor|ENSGALT00000038039|m.8076:233-296;PF07716.12|bZIP_2|Basic region leucine zipper|ENSGALT00000038039|m.8076:238-293;PF03131.14|bZIP_Maf|bZIP Maf transcription factor|ENSGALT00000038039|m.8076:231-295
ENSGALG00000010879	8.051787141	19.72746363	-1.291765011	1.54E-40	4.00E-39	down	yes	7.914329578	7.742271411	8.498760432	21.35227091	18.98301603	18.84710394	8	26692555	26971644	+	FGGY	protein_coding	GO:0019321|pentose metabolic process; GO:0046835|carbohydrate phosphorylation; GO:0070050|neuron cellular homeostasis	GO:0005623|cell	GO:0019150|D-ribulokinase activity	--	--	2164	XP_015146650.1	XP_015146650.1 FGGY carbohydrate kinase domain-containing protein isoform X1 [Gallus gallus]	sp|Q96C11|FGGY_HUMAN	sp|Q96C11|FGGY_HUMAN FGGY carbohydrate kinase domain-containing protein OS=Homo sapiens GN=FGGY PE=1 SV=2	_	_	_	_	_	"PF02782.13|FGGY_C|FGGY family of carbohydrate kinases, C-terminal domain|ENSGALT00000053156|m.8073:290-496;PF00370.18|FGGY_N|FGGY family of carbohydrate kinases, N-terminal domain|ENSGALT00000053156|m.8073:11-267"
ENSGALG00000010881	0.062606584	3.077364279	-5.410131519	3.11E-38	7.26E-37	down	yes	0.11362835	0	0.074191403	3.132311892	2.837614558	3.262166387	5	45556294	45580842	-	ASB2	protein_coding	GO:0000209|protein polyubiquitination; GO:0006511|ubiquitin-dependent protein catabolic process; GO:0007165|signal transduction; GO:0016567|protein ubiquitination; GO:0035556|intracellular signal transduction; GO:0035914|skeletal muscle cell differentiation; GO:0043687|post-translational protein modification; GO:0045445|myoblast differentiation	GO:0000151|ubiquitin ligase complex; GO:0005829|cytosol; GO:0031466|Cul5-RING ubiquitin ligase complex	GO:0061630|ubiquitin protein ligase activity	ko:K10324|ASB2	--	2561	XP_015143246.1	XP_015143246.1 ankyrin repeat and SOCS box protein 2 [Gallus gallus]	sp|Q96Q27|ASB2_HUMAN	sp|Q96Q27|ASB2_HUMAN Ankyrin repeat and SOCS box protein 2 OS=Homo sapiens GN=ASB2 PE=1 SV=1	9031.ENSGALP00000017666	ankyrin repeat and SOCS box-containing 2	COG0666	KOG0504	_	PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000106802|m.3783:61-151;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000106802|m.3783:155-217;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000106802|m.3783:187-250;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000106802|m.3783:225-308;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000106802|m.3783:258-348;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000106802|m.3783:323-419;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000106802|m.3783:124-175;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000106802|m.3783:169-205;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000106802|m.3783:223-274;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000106802|m.3783:270-307;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000106802|m.3783:321-381;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000106802|m.3783:188-214;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000106802|m.3783:220-248;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000106802|m.3783:256-281;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000106802|m.3783:319-346;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000106802|m.3783:141-195;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000106802|m.3783:240-294;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000106802|m.3783:256-284;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000106802|m.3783:319-346;PF07525.13|SOCS_box|SOCS box|ENSGALT00000106802|m.3783:542-580
ENSGALG00000010901	0.617016901	0.191064055	1.640849144	1.22E-05	3.39E-05	up	yes	0.515087296	0.729575193	0.606388214	0.101277966	0.171305916	0.300608282	2	30069508	30103222	+	ENSGALG00000010901	protein_coding	--	GO:0016021|integral component of membrane; GO:0016324|apical plasma membrane; GO:0046581|intercellular canaliculus	GO:0005524|ATP binding; GO:0008559|ATPase-coupled xenobiotic transmembrane transporter activity; GO:0090554|phosphatidylcholine floppase activity; GO:0090555|phosphatidylethanolamine flippase activity; GO:0099038|ceramide floppase activity	"ko:K05658|ABCB1,CD243"	ko02010|ABC transporters; ko04976|Bile secretion; ko05206|MicroRNAs in cancer	4501	XP_418707.5	XP_418707.5 ATP-binding cassette sub-family B member 5 isoform X1 [Gallus gallus]	sp|P21448|MDR1_CRIGR	sp|P21448|MDR1_CRIGR Multidrug resistance protein 1 OS=Cricetulus griseus GN=ABCB1 PE=1 SV=2	9031.ENSGALP00000017711	similar to multidrug resistance protein 1a	COG1132	KOG0055	_	PF00664.20|ABC_membrane|ABC transporter transmembrane region|ENSGALT00000017732|m.165:77-370;PF00664.20|ABC_membrane|ABC transporter transmembrane region|ENSGALT00000017732|m.165:758-1032;PF00005.24|ABC_tran|ABC transporter|ENSGALT00000017732|m.165:437-586;PF00005.24|ABC_tran|ABC transporter|ENSGALT00000017732|m.165:1099-1250
ENSGALG00000010903	0.316636577	1.880922582	-2.533332037	8.05E-28	1.15E-26	down	yes	0.331837718	0.356266137	0.261805877	1.783145092	1.949860412	1.90976224	4	45493922	45604213	+	RASGEF1B	protein_coding	GO:0007264|small GTPase mediated signal transduction; GO:0043547|positive regulation of GTPase activity	GO:0005769|early endosome; GO:0005770|late endosome; GO:0030496|midbody	GO:0005088|Ras guanyl-nucleotide exchange factor activity	--	--	3389	XP_025005559.1	XP_025005559.1 ras-GEF domain-containing family member 1B isoform X1 [Gallus gallus]	sp|Q5RC04|RGF1B_PONAB	sp|Q5RC04|RGF1B_PONAB Ras-GEF domain-containing family member 1B OS=Pongo abelii GN=RASGEF1B PE=2 SV=2	9031.ENSGALP00000017713	similar to RASGEF1B protein	_	KOG3541	_	PF00617.16|RasGEF|RasGEF domain|ENSGALT00000102274|m.500:208-401;PF00618.17|RasGEF_N|RasGEF N-terminal motif|ENSGALT00000102274|m.500:39-135
ENSGALG00000010935	0.088755733	0.228718069	-1.27337136	0.002562731	0.005047348	down	yes	0.068459622	0.128275228	0.06953235	0.197424048	0.270755303	0.217974857	1	39965497	40063282	+	PTPRQ	protein_coding	GO:0045598|regulation of fat cell differentiation	GO:0016021|integral component of membrane	GO:0004725|protein tyrosine phosphatase activity	ko:K16910|PTPRQ	--	6927	XP_015138820.1	XP_015138820.1 phosphatidylinositol phosphatase PTPRQ isoform X3 [Gallus gallus]	sp|Q9UMZ3|PTPRQ_HUMAN	sp|Q9UMZ3|PTPRQ_HUMAN Phosphatidylinositol phosphatase PTPRQ OS=Homo sapiens GN=PTPRQ PE=1 SV=2	9031.ENSGALP00000017773	"protein tyrosine phosphatase, receptor type, Q"	COG5599	KOG0196;KOG0791;KOG4228	_	PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000017794|m.974:1-76;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000017794|m.974:91-176;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000017794|m.974:340-418;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000017794|m.974:589-668;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000017794|m.974:685-764;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000017794|m.974:872-948;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000017794|m.974:966-1053;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000017794|m.974:1071-1149;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000017794|m.974:1169-1246;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000017794|m.974:1260-1339;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000017794|m.974:1358-1432;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000017794|m.974:1446-1544;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000017794|m.974:1559-1636;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000017794|m.974:1661-1750;PF00102.24|Y_phosphatase|Protein-tyrosine phosphatase|ENSGALT00000017794|m.974:2036-2266
ENSGALG00000010977	2.352900207	1.107864517	1.079813355	0.000292866	0.000669574	up	yes	2.54400512	2.149798982	2.36489652	1.200208404	0.903824924	1.219560222	2	31327774	31334403	+	FAM221A	protein_coding	--	--	--	--	--	1222	XP_418719.1	XP_418719.1 protein FAM221A [Gallus gallus]	sp|Q8C790|F221A_MOUSE	sp|Q8C790|F221A_MOUSE Protein FAM221A OS=Mus musculus GN=Fam221a PE=1 SV=1	9031.ENSGALP00000017862	chromosome 7 open reading frame 46	_	_	NOG45810	PF14753.3|DUF4475|Domain of unknown function (DUF4475)|ENSGALT00000017883|m.223:63-256
ENSGALG00000010983	0.676657757	1.89670509	-1.473418602	0.002611314	0.005138009	down	yes	0.699439236	0.797734708	0.532799327	1.461626674	2.059324368	2.169164228	2	31464055	31472130	+	NPY	protein_coding	GO:0007218|neuropeptide signaling pathway; GO:0007267|cell-cell signaling; GO:0007631|feeding behavior; GO:0008217|regulation of blood pressure; GO:0021954|central nervous system neuron development; GO:0021987|cerebral cortex development; GO:0031175|neuron projection development; GO:0032098|regulation of appetite	GO:0005615|extracellular space; GO:0005794|Golgi apparatus	GO:0001664|G protein-coupled receptor binding; GO:0005184|neuropeptide hormone activity	ko:K05232|NPY	ko04024|cAMP signaling pathway; ko04920|Adipocytokine signaling pathway; ko04923|Regulation of lipolysis in adipocytes; ko05034|Alcoholism	678	NP_990804.1	NP_990804.1 pro-neuropeptide Y precursor [Gallus gallus]	sp|P28673|NPY_CHICK	sp|P28673|NPY_CHICK Pro-neuropeptide Y OS=Gallus gallus GN=NPY PE=3 SV=1	9031.ENSGALP00000017870	Neuropeptide Y Precursor [Contains Neuropeptide Y(Neuropeptide tyrosine)(NPY);C-flanking pep [...] 	_	_	NOG45909	_
ENSGALG00000011007	2.788967247	8.741497089	-1.64463523	1.45E-37	3.28E-36	down	yes	2.578059932	2.636995596	3.151846213	7.793776602	9.132462159	9.298252506	2	31647411	31714056	-	OSBPL3	protein_coding	GO:0006699|bile acid biosynthetic process	GO:0005789|endoplasmic reticulum membrane; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0016020|membrane; GO:0031965|nuclear membrane; GO:0032433|filopodium tip; GO:0097038|perinuclear endoplasmic reticulum	GO:0015248|sterol transporter activity; GO:0015485|cholesterol binding	"ko:K20463|OSBPL3_6_7,ORP3_6_7"	--	3058	XP_015137321.1	XP_015137321.1 oxysterol-binding protein-related protein 3 isoform X2 [Gallus gallus]	sp|Q9H4L5|OSBL3_HUMAN	sp|Q9H4L5|OSBL3_HUMAN Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3 PE=1 SV=1	9031.ENSGALP00000017902	oxysterol binding protein-like 3	_	KOG1737	_	PF01237.15|Oxysterol_BP|Oxysterol-binding protein|ENSGALT00000078181|m.234:528-871;PF15409.3|PH_8|Pleckstrin homology domain|ENSGALT00000078181|m.234:55-141;PF00169.26|PH|PH domain|ENSGALT00000078181|m.234:53-141
ENSGALG00000011035	19.31043089	8.118646754	1.24904017	8.63E-22	8.96E-21	up	yes	24.37973991	15.30981758	18.24173517	8.144386296	7.90860355	8.302950416	8	28615900	28626590	+	AK4	protein_coding	GO:0001889|liver development; GO:0006165|nucleoside diphosphate phosphorylation; GO:0007420|brain development; GO:0009142|nucleoside triphosphate biosynthetic process; GO:0015949|nucleobase-containing small molecule interconversion; GO:0042493|response to drug; GO:0046033|AMP metabolic process; GO:0046034|ATP metabolic process; GO:0046039|GTP metabolic process	GO:0005739|mitochondrion; GO:0005759|mitochondrial matrix; GO:0070062|extracellular exosome	GO:0004017|adenylate kinase activity; GO:0004550|nucleoside diphosphate kinase activity; GO:0005524|ATP binding; GO:0005525|GTP binding; GO:0046899|nucleoside triphosphate adenylate kinase activity; GO:0050145|nucleoside monophosphate kinase activity	"ko:K00939|adk,AK"	ko00230|Purine metabolism; ko00730|Thiamine metabolism; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko01130|Biosynthesis of antibiotics	2801	XP_422526.4	"XP_422526.4 LOW QUALITY PROTEIN: adenylate kinase 4, mitochondrial [Gallus gallus]"	sp|P27144|KAD4_HUMAN	"sp|P27144|KAD4_HUMAN Adenylate kinase 4, mitochondrial OS=Homo sapiens GN=AK4 PE=1 SV=1"	9544.ENSMMUP00000001438	adenylate kinase 4	COG0563	KOG3078	_	"PF00406.19|ADK|Adenylate kinase|ENSGALT00000017973|m.8151:4-117;PF05191.11|ADK_lid|Adenylate kinase, active site lid|ENSGALT00000017973|m.8151:54-89"
ENSGALG00000011080	3.743432506	1.419911843	1.392284336	0.001454907	0.002990752	up	yes	2.391965088	4.664337447	4.173994982	1.46765012	1.952410737	0.839674673	5	46550123	46571687	+	BDKRB2	protein_coding	GO:0006939|smooth muscle contraction; GO:0006950|response to stress; GO:0042310|vasoconstriction	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0004947|bradykinin receptor activity	ko:K03916|BDKRB2	ko04020|Calcium signaling pathway; ko04022|cGMP-PKG signaling pathway; ko04071|Sphingolipid signaling pathway; ko04080|Neuroactive ligand-receptor interaction; ko04610|Complement and coagulation cascades; ko04750|Inflammatory mediator regulation of TRP channels; ko04810|Regulation of actin cytoskeleton; ko04961|Endocrine and other factor-regulated calcium reabsorption; ko05142|Chagas disease (American trypanosomiasis); ko05200|Pathways in cancer	2982	XP_015143038.1	XP_015143038.1 B2 bradykinin receptor isoform X1 [Gallus gallus]	sp|Q28642|BKRB2_RABIT	sp|Q28642|BKRB2_RABIT B2 bradykinin receptor OS=Oryctolagus cuniculus GN=BDKRB2 PE=3 SV=1	9031.ENSGALP00000018030	bradykinin receptor B2 	_	KOG3656	_	PF00001.18|7tm_1|7 transmembrane receptor (rhodopsin family)|ENSGALT00000091205|m.3811:69-324
ENSGALG00000011094	38.3152182	93.18975511	-1.282032158	1.42E-100	1.79E-98	down	yes	38.65940785	39.21925887	37.06698788	90.33362388	96.49366207	92.74197938	8	28854640	28875786	+	PDE4B	protein_coding	GO:0001780|neutrophil homeostasis; GO:0006198|cAMP catabolic process; GO:0030593|neutrophil chemotaxis; GO:0032729|positive regulation of interferon-gamma production; GO:0032743|positive regulation of interleukin-2 production; GO:0035690|cellular response to drug; GO:0050852|T cell receptor signaling pathway; GO:0050900|leukocyte migration; GO:0071222|cellular response to lipopolysaccharide; GO:0071872|cellular response to epinephrine stimulus; GO:0086004|regulation of cardiac muscle cell contraction; GO:1901841|regulation of high voltage-gated calcium channel activity; GO:1901898|negative regulation of relaxation of cardiac muscle	GO:0000930|gamma-tubulin complex; GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005813|centrosome; GO:0005829|cytosol; GO:0008021|synaptic vesicle; GO:0014069|postsynaptic density; GO:0016020|membrane; GO:0030018|Z disc; GO:0043197|dendritic spine; GO:0048471|perinuclear region of cytoplasm; GO:0060076|excitatory synapse; GO:0071944|cell periphery	"GO:0004115|3',5'-cyclic-AMP phosphodiesterase activity; GO:0030552|cAMP binding; GO:0043015|gamma-tubulin binding; GO:0044325|ion channel binding; GO:0046872|metal ion binding"	ko:K13293|PDE4	ko00230|Purine metabolism; ko04024|cAMP signaling pathway; ko05032|Morphine addiction	3098	NP_001026462.1	"NP_001026462.1 cAMP-specific 3',5'-cyclic phosphodiesterase 4B [Gallus gallus]"	sp|P14646|PDE4B_RAT	"sp|P14646|PDE4B_RAT cAMP-specific 3',5'-cyclic phosphodiesterase 4B OS=Rattus norvegicus GN=Pde4b PE=1 SV=4"	_	_	_	_	_	PF00233.16|PDEase_I|3'5'-cyclic nucleotide phosphodiesterase|ENSGALT00000018074|m.8160:234-475
ENSGALG00000011099	0.300010175	1.017006513	-1.728057856	1.14E-06	3.63E-06	down	yes	0.286468408	0.308057032	0.305505087	1.257136679	0.770421015	1.023461843	7	21075293	21113292	+	FAP	protein_coding	GO:0001525|angiogenesis; GO:0006508|proteolysis; GO:0007155|cell adhesion; GO:0010710|regulation of collagen catabolic process; GO:0010716|negative regulation of extracellular matrix disassembly; GO:0043542|endothelial cell migration; GO:0051603|proteolysis involved in cellular protein catabolic process; GO:0051917|regulation of fibrinolysis; GO:0060244|negative regulation of cell proliferation involved in contact inhibition; GO:0071158|positive regulation of cell cycle arrest; GO:0071850|mitotic cell cycle arrest; GO:0097325|melanocyte proliferation; GO:1900119|positive regulation of execution phase of apoptosis; GO:1902362|melanocyte apoptotic process; GO:1903054|negative regulation of extracellular matrix organization	GO:0005615|extracellular space; GO:0005737|cytoplasm; GO:0005886|plasma membrane; GO:0005925|focal adhesion; GO:0009986|cell surface; GO:0016021|integral component of membrane; GO:0030027|lamellipodium; GO:0031258|lamellipodium membrane; GO:0032587|ruffle membrane; GO:0045177|apical part of cell; GO:0045178|basal part of cell; GO:0071438|invadopodium membrane	GO:0002020|protease binding; GO:0004175|endopeptidase activity; GO:0004222|metalloendopeptidase activity; GO:0004252|serine-type endopeptidase activity; GO:0005178|integrin binding; GO:0008233|peptidase activity; GO:0008236|serine-type peptidase activity; GO:0008239|dipeptidyl-peptidase activity; GO:0042803|protein homodimerization activity; GO:0046983|protein dimerization activity	ko:K08674|FAP	--	2759	NP_001180568.1	NP_001180568.1 prolyl endopeptidase FAP [Gallus gallus]	sp|Q12884|SEPR_HUMAN	sp|Q12884|SEPR_HUMAN Prolyl endopeptidase FAP OS=Homo sapiens GN=FAP PE=1 SV=5	9031.ENSGALP00000018061	"fibroblast activation protein, alpha"	COG1506	KOG2100	_	PF00930.18|DPPIV_N|Dipeptidyl peptidase IV (DPP IV) N-terminal region|ENSGALT00000018083|m.6253:105-471;PF00326.18|Peptidase_S9|Prolyl oligopeptidase family|ENSGALT00000018083|m.6253:553-756
ENSGALG00000011109	0.036492157	0.312824848	-2.79569237	3.63E-10	1.64E-09	down	yes	0.012483082	0.073220852	0.023772536	0.258251877	0.348059438	0.332163229	4	45932534	46032124	-	MAPK10	protein_coding	GO:0006468|protein phosphorylation; GO:0007165|signal transduction; GO:0007254|JNK cascade; GO:0009416|response to light stimulus; GO:0010468|regulation of gene expression; GO:0038095|Fc-epsilon receptor signaling pathway; GO:0042752|regulation of circadian rhythm; GO:0048511|rhythmic process; GO:0048666|neuron development; GO:0051090|regulation of DNA-binding transcription factor activity	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005739|mitochondrion; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0043005|neuron projection	GO:0004705|JUN kinase activity; GO:0004708|MAP kinase kinase activity; GO:0005524|ATP binding	ko:K04440|JNK	ko01522|Endocrine resistance; ko04010|MAPK signaling pathway; ko04012|ErbB signaling pathway; ko04013|MAPK signaling pathway - fly; ko04014|Ras signaling pathway; ko04024|cAMP signaling pathway; ko04068|FoxO signaling pathway; ko04071|Sphingolipid signaling pathway; ko04137|Mitophagy - animal; ko04140|Autophagy - animal; ko04141|Protein processing in endoplasmic reticulum; ko04210|Apoptosis; ko04212|Longevity regulating pathway - worm; ko04214|Apoptosis - fly; ko04215|Apoptosis - multiple species; ko04310|Wnt signaling pathway; ko04380|Osteoclast differentiation; ko04391|Hippo signaling pathway - fly; ko04510|Focal adhesion; ko04530|Tight junction; ko04620|Toll-like receptor signaling pathway; ko04621|NOD-like receptor signaling pathway; ko04622|RIG-I-like receptor signaling pathway; ko04624|Toll and Imd signaling pathway; ko04657|IL-17 signaling pathway; ko04658|Th1 and Th2 cell differentiation; ko04659|Th17 cell differentiation; ko04664|Fc epsilon RI signaling pathway; ko04668|TNF signaling pathway; ko04722|Neurotrophin signaling pathway; ko04723|Retrograde endocannabinoid signaling; ko04728|Dopaminergic synapse; ko04750|Inflammatory mediator regulation of TRP channels; ko04910|Insulin signaling pathway; ko04912|GnRH signaling pathway; ko04914|Progesterone-mediated oocyte maturation; ko04917|Prolactin signaling pathway; ko04920|Adipocytokine signaling pathway; ko04930|Type II diabetes mellitus; ko04931|Insulin resistance; ko04932|Non-alcoholic fatty liver disease (NAFLD); ko04933|AGE-RAGE signaling pathway in diabetic complications; ko05120|Epithelial cell signaling in Helicobacter pylori infection; ko05131|Shigellosis; ko05132|Salmonella infection; ko05133|Pertussis; ko05142|Chagas disease (American trypanosomiasis); ko05145|Toxoplasmosis; ko05152|Tuberculosis; ko05160|Hepatitis C; ko05161|Hepatitis B; ko05164|Influenza A; ko05168|Herpes simplex infection; ko05169|Epstein-Barr virus infection; ko05200|Pathways in cancer; ko05210|Colorectal cancer; ko05212|Pancreatic cancer; ko05231|Choline metabolism in cancer; ko05418|Fluid shear stress and atherosclerosis	8442	NP_001305154.1	NP_001305154.1 mitogen-activated protein kinase 10 isoform 1x [Gallus gallus]	sp|P53779|MK10_HUMAN	sp|P53779|MK10_HUMAN Mitogen-activated protein kinase 10 OS=Homo sapiens GN=MAPK10 PE=1 SV=2	_	_	_	_	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000056342|m.528:64-359;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000056342|m.528:67-265;PF06293.11|Kdo|Lipopolysaccharide kinase (Kdo/WaaP) family|ENSGALT00000056342|m.528:86-209
ENSGALG00000011124	0.960655348	3.851467712	-1.992118276	6.45E-21	6.35E-20	down	yes	0.838548509	1.038146279	1.005271257	3.831559185	4.990953362	2.731890588	4	46061676	46215503	-	ARHGAP24	protein_coding	"GO:0001525|angiogenesis; GO:0007165|signal transduction; GO:0030154|cell differentiation; GO:0035021|negative regulation of Rac protein signal transduction; GO:0035313|wound healing, spreading of epidermal cells; GO:0090630|activation of GTPase activity; GO:1900028|negative regulation of ruffle assembly"	GO:0005737|cytoplasm; GO:0005856|cytoskeleton; GO:0005925|focal adhesion; GO:0042995|cell projection	GO:0005096|GTPase activator activity	ko:K20642|ARHGAP22_24_25	--	3119	XP_004941172.1	XP_004941172.1 rho GTPase-activating protein 24 isoform X3 [Gallus gallus]	sp|Q8C4V1|RHG24_MOUSE	sp|Q8C4V1|RHG24_MOUSE Rho GTPase-activating protein 24 OS=Mus musculus GN=Arhgap24 PE=1 SV=2	9031.ENSGALP00000018112	Rho GTPase activating protein 24	_	KOG0930;KOG4270	_	PF00620.24|RhoGAP|RhoGAP domain|ENSGALT00000095213|m.530:61-209
ENSGALG00000011131	3.644942011	12.1076396	-1.729188281	1.80E-40	4.67E-39	down	yes	2.955367359	4.276732726	3.702725947	11.18969605	12.31123697	12.82198578	7	21452859	21480464	-	TANK	protein_coding	GO:0006508|proteolysis; GO:0006974|cellular response to DNA damage stimulus; GO:0007165|signal transduction; GO:0007249|I-kappaB kinase/NF-kappaB signaling; GO:0016032|viral process; GO:0035666|TRIF-dependent toll-like receptor signaling pathway; GO:0043124|negative regulation of I-kappaB kinase/NF-kappaB signaling; GO:0071347|cellular response to interleukin-1; GO:0071356|cellular response to tumor necrosis factor; GO:0071479|cellular response to ionizing radiation; GO:1903003|positive regulation of protein deubiquitination; GO:2000158|positive regulation of ubiquitin-specific protease activity	GO:0005829|cytosol; GO:0032991|protein-containing complex	GO:0031625|ubiquitin protein ligase binding; GO:0035800|deubiquitinase activator activity; GO:0046872|metal ion binding	ko:K12650|TANK	ko04621|NOD-like receptor signaling pathway; ko04622|RIG-I-like receptor signaling pathway	2710	NP_001264800.1	NP_001264800.1 TRAF family member-associated NF-kappa-B activator [Gallus gallus]	sp|Q92844|TANK_HUMAN	sp|Q92844|TANK_HUMAN TRAF family member-associated NF-kappa-B activator OS=Homo sapiens GN=TANK PE=1 SV=2	9031.ENSGALP00000032485	annotation not avaliable	_	_	NOG44252	PF12845.4|TBD|TBD domain|ENSGALT00000033125|m.6266:192-245
ENSGALG00000011149	2.832882202	11.02022409	-1.956035875	8.62E-69	5.45E-67	down	yes	2.294298345	3.079247563	3.1251007	10.28281872	11.88061281	10.89724074	7	21828489	21864267	+	PLA2R1	protein_coding	"GO:0001816|cytokine production; GO:0006898|receptor-mediated endocytosis; GO:0043517|positive regulation of DNA damage response, signal transduction by p53 class mediator; GO:0072593|reactive oxygen species metabolic process; GO:0090238|positive regulation of arachidonic acid secretion; GO:0090399|replicative senescence; GO:0090403|oxidative stress-induced premature senescence; GO:1900138|negative regulation of phospholipase A2 activity; GO:1900139|negative regulation of arachidonic acid secretion"	GO:0005576|extracellular region; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0009986|cell surface; GO:0043235|receptor complex; GO:0070062|extracellular exosome	GO:0004888|transmembrane signaling receptor activity; GO:0030246|carbohydrate binding; GO:0038023|signaling receptor activity; GO:0043274|phospholipase binding	"ko:K06560|MRC,CD206,CD280"	ko04145|Phagosome; ko05152|Tuberculosis	5420	NP_996866.1	NP_996866.1 secretory phospholipase A2 receptor precursor [Gallus gallus]	sp|Q13018|PLA2R_HUMAN	sp|Q13018|PLA2R_HUMAN Secretory phospholipase A2 receptor OS=Homo sapiens GN=PLA2R1 PE=1 SV=2	9031.ENSGALP00000032471	"phospholipase A2 receptor 1, 180kDa "	_	KOG4297	_	PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000033111|m.6272:244-352;PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000033111|m.6272:390-497;PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000033111|m.6272:544-641;PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000033111|m.6272:686-794;PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000033111|m.6272:828-936;PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000033111|m.6272:980-1095;PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000033111|m.6272:1131-1230;PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000033111|m.6272:1268-1376;PF00040.16|fn2|Fibronectin type II domain|ENSGALT00000033111|m.6272:176-215
ENSGALG00000011153	8.928636197	19.14658896	-1.099714061	7.32E-33	1.34E-31	down	yes	7.854411282	9.598101956	9.333395353	17.36251418	21.25263514	18.82461758	7	21882268	21921613	+	LY75	protein_coding	GO:0006897|endocytosis; GO:0006954|inflammatory response; GO:0006955|immune response	GO:0005887|integral component of plasma membrane; GO:0070062|extracellular exosome	GO:0004888|transmembrane signaling receptor activity; GO:0030246|carbohydrate binding; GO:0038023|signaling receptor activity	"ko:K06559|LY75,CD205"	--	6098	NP_001032925.1	NP_001032925.1 lymphocyte antigen 75 precursor [Gallus gallus]	sp|O60449|LY75_HUMAN	sp|O60449|LY75_HUMAN Lymphocyte antigen 75 OS=Homo sapiens GN=LY75 PE=1 SV=3	9031.ENSGALP00000037534	hypothetical protein LOC424192 	_	KOG4297	_	PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000098677|m.6275:236-341;PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000098677|m.6275:378-485;PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000098677|m.6275:529-624;PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000098677|m.6275:667-793;PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000098677|m.6275:833-930;PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000098677|m.6275:970-1089;PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000098677|m.6275:1123-1223;PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000098677|m.6275:1268-1343;PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000098677|m.6275:1412-1514;PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000098677|m.6275:1562-1668;PF00040.16|fn2|Fibronectin type II domain|ENSGALT00000098677|m.6275:167-208
ENSGALG00000011170	4.190601118	9.682516551	-1.206275497	1.05E-15	7.38E-15	down	yes	3.790725835	4.377497472	4.403580046	10.7059422	9.794892322	8.54671513	2	33838517	33863336	+	WIPF3	protein_coding	GO:0007275|multicellular organism development; GO:0007283|spermatogenesis; GO:0030154|cell differentiation	GO:0005737|cytoplasm	GO:0003779|actin binding; GO:0017124|SH3 domain binding	ko:K19475|WIPF	ko04144|Endocytosis	1647	XP_004939443.1	XP_004939443.1 WAS/WASL-interacting protein family member 3 isoform X1 [Gallus gallus]	sp|Q9Z0G8|WIPF3_RAT	sp|Q9Z0G8|WIPF3_RAT WAS/WASL-interacting protein family member 3 OS=Rattus norvegicus GN=Wipf3 PE=1 SV=1	9031.ENSGALP00000018190	annotation not avaliable	_	KOG4462	_	PF02205.17|WH2|WH2 motif|ENSGALT00000069084|m.313:43-67
ENSGALG00000011172	7.571147679	3.164477968	1.255896904	4.18E-41	1.11E-39	up	yes	8.00651384	7.53520493	7.171724269	3.148528206	2.941259034	3.403646663	7	21930914	21996451	-	ENSGALG00000011172	protein_coding	GO:0008360|regulation of cell shape; GO:0022409|positive regulation of cell-cell adhesion; GO:0030705|cytoskeleton-dependent intracellular transport; GO:0048870|cell motility; GO:0051489|regulation of filopodium assembly	GO:0001726|ruffle; GO:0005730|nucleolus; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0005938|cell cortex; GO:0016459|myosin complex; GO:0030027|lamellipodium; GO:0030175|filopodium; GO:0031527|filopodium membrane; GO:0032433|filopodium tip; GO:0043005|neuron projection; GO:0043025|neuronal cell body	"GO:0003774|motor activity; GO:0005516|calmodulin binding; GO:0005524|ATP binding; GO:0005547|phosphatidylinositol-3,4,5-trisphosphate binding; GO:0030507|spectrin binding; GO:0030898|actin-dependent ATPase activity; GO:0051015|actin filament binding; GO:0060002|plus-end directed microfilament motor activity"	ko:K12559|MYO10	ko04666|Fc gamma R-mediated phagocytosis	6660	XP_015145197.1	XP_015145197.1 unconventional myosin-X isoform X1 [Gallus gallus]	sp|F8VQB6|MYO10_MOUSE	sp|F8VQB6|MYO10_MOUSE Unconventional myosin-X OS=Mus musculus GN=Myo10 PE=1 SV=1	_	_	_	_	_	PF00063.18|Myosin_head|Myosin head (motor domain)|ENSGALT00000018214|m.6284:227-889;PF00169.26|PH|PH domain|ENSGALT00000018214|m.6284:1371-1465;PF00169.26|PH|PH domain|ENSGALT00000018214|m.6284:1553-1653;PF00784.14|MyTH4|MyTH4 domain|ENSGALT00000018214|m.6284:1745-1850;PF16735.2|MYO10_CC|Unconventional myosin-X coiled coil domain|ENSGALT00000018214|m.6284:1052-1103;PF00373.15|FERM_M|FERM central domain|ENSGALT00000018214|m.6284:1953-2115;PF15409.3|PH_8|Pleckstrin homology domain|ENSGALT00000018214|m.6284:1388-1465;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000018214|m.6284:905-925;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000018214|m.6284:952-971;PF14593.3|PH_3|PH domain|ENSGALT00000018214|m.6284:1367-1468
ENSGALG00000011177	1.947385755	4.890121427	-1.323889395	1.37E-13	8.17E-13	down	yes	1.930593971	1.795285004	2.11627829	4.596247698	5.605521966	4.468594618	1	42869836	42885028	-	ENSGALG00000011177	protein_coding	"GO:0000086|G2/M transition of mitotic cell cycle; GO:0010389|regulation of G2/M transition of mitotic cell cycle; GO:0015031|protein transport; GO:0030902|hindbrain development; GO:0030916|otic vesicle formation; GO:0042462|eye photoreceptor cell development; GO:0043312|neutrophil degranulation; GO:0045893|positive regulation of transcription, DNA-templated; GO:0048793|pronephros development; GO:0060271|cilium assembly; GO:0070201|regulation of establishment of protein localization; GO:0090316|positive regulation of intracellular protein transport; GO:0097711|ciliary basal body-plasma membrane docking"	GO:0005576|extracellular region; GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005813|centrosome; GO:0005814|centriole; GO:0005829|cytosol; GO:0016020|membrane; GO:0032391|photoreceptor connecting cilium; GO:0032991|protein-containing complex; GO:0034451|centriolar satellite; GO:0035580|specific granule lumen; GO:0035869|ciliary transition zone; GO:0036038|MKS complex; GO:0036064|ciliary basal body	GO:0042802|identical protein binding	"ko:K16533|CEP290,NPHP6"	--	2238	XP_004937659.1	XP_004937659.1 centrosomal protein of 290 kDa [Gallus gallus]	sp|O15078|CE290_HUMAN	sp|O15078|CE290_HUMAN Centrosomal protein of 290 kDa OS=Homo sapiens GN=CEP290 PE=1 SV=2	9031.ENSGALP00000018199	centrosomal protein 290kDa	_	_	NOG136455	_
ENSGALG00000011181	16.37337833	8.148301874	1.005892082	6.19E-24	7.27E-23	up	yes	15.74097668	16.90934325	16.46981505	8.339230705	8.731985885	7.373689031	2	33912328	33919576	-	FKBP14	protein_coding	GO:0036498|IRE1-mediated unfolded protein response; GO:0061077|chaperone-mediated protein folding	GO:0005737|cytoplasm; GO:0005788|endoplasmic reticulum lumen	GO:0003755|peptidyl-prolyl cis-trans isomerase activity; GO:0005509|calcium ion binding; GO:0005528|FK506 binding	ko:K09577|FKBP14	--	2303	XP_418735.1	XP_418735.1 peptidyl-prolyl cis-trans isomerase FKBP14 [Gallus gallus]	sp|Q9NWM8|FKB14_HUMAN	sp|Q9NWM8|FKB14_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP14 OS=Homo sapiens GN=FKBP14 PE=1 SV=1	9031.ENSGALP00000018209	"FK506 binding protein 14, 22 kDa"	COG0545	KOG0549	_	PF00254.25|FKBP_C|FKBP-type peptidyl-prolyl cis-trans isomerase|ENSGALT00000018231|m.321:41-131;PF13499.3|EF-hand_7|EF-hand domain pair|ENSGALT00000018231|m.321:140-205
ENSGALG00000011213	4.699668933	2.033912578	1.204292158	1.20E-12	6.66E-12	up	yes	4.640190525	4.653410993	4.80540528	1.565089418	2.388765263	2.147883053	5	48671881	48687922	-	DEGS2	protein_coding	GO:0006667|sphinganine metabolic process; GO:0030148|sphingolipid biosynthetic process; GO:0046513|ceramide biosynthetic process	GO:0005789|endoplasmic reticulum membrane; GO:0016021|integral component of membrane	GO:0000170|sphingosine hydroxylase activity; GO:0042284|sphingolipid delta-4 desaturase activity	ko:K04712|DEGS	ko00600|Sphingolipid metabolism; ko01100|Metabolic pathways; ko04071|Sphingolipid signaling pathway	2748	XP_421364.2	XP_421364.2 sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 isoform X1 [Gallus gallus]	sp|Q8R2F2|DEGS2_MOUSE	sp|Q8R2F2|DEGS2_MOUSE Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 OS=Mus musculus GN=Degs2 PE=1 SV=1	9031.ENSGALP00000018264	"degenerative spermatocyte homolog 2, lipid desaturase (Drosophila)"	_	KOG2987	_	PF00487.21|FA_desaturase|Fatty acid desaturase|ENSGALT00000018286|m.3847:71-296;PF08557.7|Lipid_DES|Sphingolipid Delta4-desaturase (DES)|ENSGALT00000018286|m.3847:11-46
ENSGALG00000011220	1.442671867	2.928336257	-1.016290644	1.56E-05	4.26E-05	down	yes	1.171826796	1.793735904	1.362452901	3.162793601	3.479964491	2.14225068	5	48730241	48739091	-	SLC25A29	protein_coding	GO:0006839|mitochondrial transport; GO:0006844|acyl carnitine transport; GO:0006865|amino acid transport; GO:0015822|ornithine transport; GO:0089709|L-histidine transmembrane transport; GO:1903400|L-arginine transmembrane transport; GO:1903401|L-lysine transmembrane transport; GO:1990575|mitochondrial L-ornithine transmembrane transport	GO:0005739|mitochondrion; GO:0005743|mitochondrial inner membrane; GO:0016021|integral component of membrane	GO:0005289|high-affinity arginine transmembrane transporter activity; GO:0005292|high-affinity lysine transmembrane transporter activity; GO:0015171|amino acid transmembrane transporter activity; GO:0015174|basic amino acid transmembrane transporter activity; GO:0015227|acyl carnitine transmembrane transporter activity	"ko:K15109|SLC25A20_29,CACT,CACL,CRC1"	--	2563	XP_421366.1	XP_421366.1 mitochondrial basic amino acids transporter [Gallus gallus]	sp|Q5HZE0|MCATL_RAT	sp|Q5HZE0|MCATL_RAT Mitochondrial basic amino acids transporter OS=Rattus norvegicus GN=Slc25a29 PE=2 SV=1	9031.ENSGALP00000018274	"solute carrier family 25, member 29"	_	KOG0762	_	PF00153.24|Mito_carr|Mitochondrial carrier protein|ENSGALT00000018296|m.3850:4-89;PF00153.24|Mito_carr|Mitochondrial carrier protein|ENSGALT00000018296|m.3850:91-183;PF00153.24|Mito_carr|Mitochondrial carrier protein|ENSGALT00000018296|m.3850:194-279
ENSGALG00000011225	1.616587609	0.594268699	1.42858641	0.002466738	0.00487338	up	yes	1.810690347	1.062079788	1.97699269	0.635682034	0.787733556	0.359390508	5	48749877	48755650	+	SLC25A47	protein_coding	GO:0006839|mitochondrial transport	GO:0005739|mitochondrion; GO:0005743|mitochondrial inner membrane; GO:0016021|integral component of membrane	GO:0022857|transmembrane transporter activity	ko:K15123|SLC25A45_47	--	873	XP_421367.3	XP_421367.3 solute carrier family 25 member 47 isoform X5 [Gallus gallus]	sp|Q6J329|S2547_RAT	sp|Q6J329|S2547_RAT Solute carrier family 25 member 47 OS=Rattus norvegicus GN=Slc25a47 PE=2 SV=1	9031.ENSGALP00000031875	chromosome 14 open reading frame 68	_	KOG0762	_	PF00153.24|Mito_carr|Mitochondrial carrier protein|ENSGALT00000032511|m.3852:25-72;PF00153.24|Mito_carr|Mitochondrial carrier protein|ENSGALT00000032511|m.3852:94-187;PF00153.24|Mito_carr|Mitochondrial carrier protein|ENSGALT00000032511|m.3852:196-282
ENSGALG00000011228	62.92154517	128.8812971	-1.034299583	7.22E-44	2.12E-42	down	yes	56.3413754	67.74377559	64.67948452	133.663294	120.4213161	132.5592811	5	48761498	48777907	-	WARS	protein_coding	GO:0001525|angiogenesis; GO:0006436|tryptophanyl-tRNA aminoacylation	GO:0005737|cytoplasm	GO:0004830|tryptophan-tRNA ligase activity; GO:0005524|ATP binding	"ko:K01867|WARS,trpS"	ko00970|Aminoacyl-tRNA biosynthesis	1992	XP_421368.1	"XP_421368.1 tryptophan--tRNA ligase, cytoplasmic [Gallus gallus]"	sp|Q5R4J1|SYWC_PONAB	"sp|Q5R4J1|SYWC_PONAB Tryptophan--tRNA ligase, cytoplasmic OS=Pongo abelii GN=WARS PE=2 SV=2"	9031.ENSGALP00000018294	tryptophanyl-tRNA synthetase	COG0180	KOG2145	_	PF00579.22|tRNA-synt_1b|tRNA synthetases class I (W and Y)|ENSGALT00000018316|m.3853:155-442;PF00458.17|WHEP-TRS|WHEP-TRS domain|ENSGALT00000018316|m.3853:17-68
ENSGALG00000011237	12.50069414	5.151094843	1.27741279	8.48E-21	8.29E-20	up	yes	11.85697347	13.54978686	12.09532209	6.017079022	4.385339469	5.050866038	2	34293909	34296747	-	DPH3P1	protein_coding	GO:0017183|peptidyl-diphthamide biosynthetic process from peptidyl-histidine; GO:0050709|negative regulation of protein secretion; GO:0051099|positive regulation of binding	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005829|cytosol	GO:0046872|metal ion binding	"ko:K15455|DPH3,KTI11"	--	1782	NP_001289035.1	NP_001289035.1 DPH3 homolog [Gallus gallus]	sp|Q8K0W9|DPH3_MOUSE	sp|Q8K0W9|DPH3_MOUSE DPH3 homolog OS=Mus musculus GN=Dph3 PE=1 SV=1	9031.ENSGALP00000018305	"DPH3, KTI11 homolog (S. cerevisiae)"	COG5216	KOG2923	_	_
ENSGALG00000011254	2.782582437	8.938716909	-1.68008097	3.12E-31	5.28E-30	down	yes	3.520861214	2.831609082	1.995277016	8.729814549	9.227038148	8.85929803	2	35150112	35241163	-	SATB1	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006325|chromatin organization; GO:0006338|chromatin remodeling; GO:0006351|transcription, DNA-templated; GO:0008544|epidermis development; GO:0016032|viral process; GO:0016571|histone methylation; GO:0043367|CD4-positive, alpha-beta T cell differentiation; GO:0043374|CD8-positive, alpha-beta T cell differentiation; GO:0050798|activated T cell proliferation; GO:0060004|reflex; GO:0097194|execution phase of apoptosis"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005720|nuclear heterochromatin; GO:0016363|nuclear matrix; GO:0016604|nuclear body; GO:0016605|PML body	"GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding; GO:0001227|DNA-binding transcription repressor activity, RNA polymerase II-specific; GO:0003682|chromatin binding; GO:0003690|double-stranded DNA binding"	--	--	3429	NP_001186573.1	NP_001186573.1 DNA-binding protein SATB1 [Gallus gallus]	sp|Q01826|SATB1_HUMAN	sp|Q01826|SATB1_HUMAN DNA-binding protein SATB1 OS=Homo sapiens GN=SATB1 PE=1 SV=1	9031.ENSGALP00000018340	SATB homeobox 1	_	KOG3755	_	PF02376.12|CUT|CUT domain|ENSGALT00000018362|m.349:368-445;PF02376.12|CUT|CUT domain|ENSGALT00000018362|m.349:493-567;PF16557.2|CUTL|CUT1-like DNA-binding domain of SATB|ENSGALT00000018362|m.349:177-247;PF16534.2|ULD|Ubiquitin-like oligomerisation domain of SATB|ENSGALT00000018362|m.349:73-170;PF00046.26|Homeobox|Homeobox domain|ENSGALT00000018362|m.349:637-692
ENSGALG00000011288	3.363876056	10.82897973	-1.683750082	1.03E-45	3.24E-44	down	yes	3.08872496	3.216079275	3.786823934	11.17132978	10.2424737	11.0731357	3	41973928	41987008	+	DACT2	protein_coding	GO:0002244|hematopoietic progenitor cell differentiation; GO:0003382|epithelial cell morphogenesis; GO:0007162|negative regulation of cell adhesion; GO:0043588|skin development; GO:0072061|inner medullary collecting duct development; GO:1900108|negative regulation of nodal signaling pathway	GO:0005739|mitochondrion	GO:0005080|protein kinase C binding; GO:0008013|beta-catenin binding; GO:0008134|transcription factor binding; GO:0051018|protein kinase A binding; GO:0070097|delta-catenin binding	--	--	2883	XP_015139850.1	XP_015139850.1 dapper homolog 2 [Gallus gallus]	sp|Q7TN08|DACT2_MOUSE	sp|Q7TN08|DACT2_MOUSE Dapper homolog 2 OS=Mus musculus GN=Dact2 PE=1 SV=2	9031.ENSGALP00000018395	Dapper-like protein 2 Fragment 	_	_	NOG83484	PF15268.3|Dapper|Dapper|ENSGALT00000057441|m.11805:164-960
ENSGALG00000011291	19.45316974	49.69427323	-1.352623205	2.36E-51	8.89E-50	down	yes	20.01583559	19.93780542	18.40586822	55.63452157	43.53115934	49.91713878	2	37152397	37175363	+	NR1D2	protein_coding	"GO:0006355|regulation of transcription, DNA-templated; GO:0006367|transcription initiation from RNA polymerase II promoter; GO:0019216|regulation of lipid metabolic process; GO:0042752|regulation of circadian rhythm; GO:0045892|negative regulation of transcription, DNA-templated; GO:0045893|positive regulation of transcription, DNA-templated; GO:0048511|rhythmic process; GO:0050727|regulation of inflammatory response; GO:0055088|lipid homeostasis; GO:0097009|energy homeostasis; GO:2001014|regulation of skeletal muscle cell differentiation"	GO:0005634|nucleus; GO:0005654|nucleoplasm	"GO:0000980|RNA polymerase II distal enhancer sequence-specific DNA binding; GO:0001046|core promoter sequence-specific DNA binding; GO:0001227|DNA-binding transcription repressor activity, RNA polymerase II-specific; GO:0003707|steroid hormone receptor activity; GO:0004879|nuclear receptor activity; GO:0008270|zinc ion binding"	ko:K08531|NR1D2	--	2606	NP_990536.2	NP_990536.2 nuclear receptor subfamily 1 group D member 2 precursor [Gallus gallus]	sp|Q14995|NR1D2_HUMAN	sp|Q14995|NR1D2_HUMAN Nuclear receptor subfamily 1 group D member 2 OS=Homo sapiens GN=NR1D2 PE=1 SV=3	9031.ENSGALP00000018398	"nuclear receptor subfamily 1, group D, member 2 "	_	KOG4846	_	"PF00105.15|zf-C4|Zinc finger, C4 type (two domains)|ENSGALT00000031164|m.379:115-184;PF00104.27|Hormone_recep|Ligand-binding domain of nuclear hormone receptor|ENSGALT00000031164|m.379:412-585"
ENSGALG00000011298	1.728570545	4.488773047	-1.37162998	1.87E-19	1.70E-18	down	yes	1.75240939	1.600640752	1.832661494	4.804088395	4.710536863	3.951693884	2	37462364	37785654	+	RARB	protein_coding	"GO:0006351|transcription, DNA-templated"	GO:0005634|nucleus	GO:0003707|steroid hormone receptor activity; GO:0004879|nuclear receptor activity; GO:0008270|zinc ion binding; GO:0043565|sequence-specific DNA binding	"ko:K08528|RARB,NR1B2"	ko05200|Pathways in cancer; ko05222|Small cell lung cancer; ko05223|Non-small cell lung cancer	2881	XP_003207239.1	XP_003207239.1 PREDICTED: retinoic acid receptor beta isoform X3 [Meleagris gallopavo]	sp|Q9W6B3|RARB_COTJA	sp|Q9W6B3|RARB_COTJA Retinoic acid receptor beta OS=Coturnix japonica GN=RARB PE=2 SV=1	59729.ENSTGUP00000003501	Retinoic acid receptor beta (RAR-beta)(Nuclear receptor subfamily 1 group B member 2)(RAR-ep [...] 	_	KOG3575	_	"PF00105.15|zf-C4|Zinc finger, C4 type (two domains)|ENSGALT00000054548|m.386:66-134;PF00104.27|Hormone_recep|Ligand-binding domain of nuclear hormone receptor|ENSGALT00000054548|m.386:206-378"
ENSGALG00000011299	0.673346929	1.371291817	-1.015328029	0.003881403	0.007405494	down	yes	0.818502355	0.500105531	0.7014329	1.475249602	1.267882535	1.370743313	3	42171065	42196994	-	KIF25	protein_coding	GO:0007018|microtubule-based movement; GO:0046603|negative regulation of mitotic centrosome separation; GO:0051289|protein homotetramerization; GO:0051294|establishment of spindle orientation; GO:0051647|nucleus localization	GO:0005737|cytoplasm; GO:0005813|centrosome; GO:0005874|microtubule	"GO:0005524|ATP binding; GO:0008017|microtubule binding; GO:0008569|ATP-dependent microtubule motor activity, minus-end-directed"	ko:K18627|KIF25	--	1545	XP_004935583.2	XP_004935583.2 kinesin-like protein KIF25 [Gallus gallus]	sp|Q4R918|KIF25_MACFA	sp|Q4R918|KIF25_MACFA Kinesin-like protein KIF25 OS=Macaca fascicularis GN=KIF25 PE=1 SV=1	9031.ENSGALP00000018409	kinesin family member 25	COG5059	KOG0239	_	PF00225.20|Kinesin|Kinesin motor domain|ENSGALT00000018431|m.11808:110-485;PF16796.2|Microtub_bd|Microtubule binding|ENSGALT00000018431|m.11808:67-252
ENSGALG00000011306	0.297255603	1.10174781	-1.855318337	9.32E-06	2.64E-05	down	yes	0.125335607	0.422722409	0.343708795	1.065471608	1.278900179	0.960871644	7	22170600	22175002	-	DES	protein_coding	GO:0045107|intermediate filament polymerization; GO:0045109|intermediate filament organization	GO:0005737|cytoplasm; GO:0005882|intermediate filament; GO:0014704|intercalated disc; GO:0030018|Z disc; GO:0042383|sarcolemma; GO:0045098|type III intermediate filament; GO:0097433|dense body	GO:0005198|structural molecule activity	ko:K07610|DES	ko05410|Hypertrophic cardiomyopathy (HCM); ko05412|Arrhythmogenic right ventricular cardiomyopathy (ARVC); ko05414|Dilated cardiomyopathy	2102	XP_010711942.1	XP_010711942.1 PREDICTED: desmin [Meleagris gallopavo]	sp|P02542|DESM_CHICK	sp|P02542|DESM_CHICK Desmin OS=Gallus gallus GN=DES PE=1 SV=1	28377.ENSACAP00000013655	desmin	_	KOG0977	_	PF00038.18|Filament|Intermediate filament protein|ENSGALT00000018446|m.6353:99-407;PF04732.11|Filament_head|Intermediate filament head (DNA binding) region|ENSGALT00000018446|m.6353:9-98
ENSGALG00000011319	0.473345205	1.323734631	-1.464345813	4.74E-11	2.30E-10	down	yes	0.41523463	0.488722997	0.516077987	1.282400084	1.253286731	1.435517078	4	47983446	48374220	+	ADGRL3	protein_coding	GO:0001764|neuron migration; GO:0007166|cell surface receptor signaling pathway; GO:0007416|synapse assembly; GO:0098742|cell-cell adhesion via plasma-membrane adhesion molecules	GO:0005887|integral component of plasma membrane; GO:0005911|cell-cell junction; GO:0030424|axon	GO:0004930|G protein-coupled receptor activity; GO:0005509|calcium ion binding; GO:0030246|carbohydrate binding	ko:K04594|LPHN3	--	4822	XP_015131935.1	XP_015131935.1 adhesion G protein-coupled receptor L3 isoform X1 [Gallus gallus]	sp|O97827|AGRL3_BOVIN	sp|O97827|AGRL3_BOVIN Adhesion G protein-coupled receptor L3 OS=Bos taurus GN=ADGRL3 PE=2 SV=1	_	_	_	_	_	"PF02354.13|Latrophilin|Latrophilin Cytoplasmic C-terminal region|ENSGALT00000077690|m.604:1141-1519;PF02191.13|OLF|Olfactomedin-like domain|ENSGALT00000077690|m.604:140-391;PF00002.21|7tm_2|7 transmembrane receptor (Secretin family)|ENSGALT00000077690|m.604:877-1120;PF16489.2|GAIN|GPCR-Autoproteolysis INducing (GAIN) domain|ENSGALT00000077690|m.604:569-789;PF02140.15|Gal_Lectin|Galactose binding lectin domain|ENSGALT00000077690|m.604:43-123;PF01825.18|GPS|GPCR proteolysis site, GPS, motif|ENSGALT00000077690|m.604:817-861;PF02793.19|HRM|Hormone receptor domain|ENSGALT00000077690|m.604:497-553"
ENSGALG00000011320	3.020525137	8.761012897	-1.533175649	2.88E-35	5.81E-34	down	yes	2.681687138	3.396190131	2.983698141	9.384076056	8.291943791	8.607018843	1	45195312	45317916	-	TMCC3	protein_coding	--	GO:0016021|integral component of membrane	--	--	--	2932	XP_004937688.1	XP_004937688.1 transmembrane and coiled-coil domain protein 3 isoform X3 [Gallus gallus]	sp|Q9ULS5|TMCC3_HUMAN	sp|Q9ULS5|TMCC3_HUMAN Transmembrane and coiled-coil domain protein 3 OS=Homo sapiens GN=TMCC3 PE=2 SV=3	9031.ENSGALP00000018449	transmembrane and coiled-coil domain family 3	_	KOG3850	_	PF10267.6|Tmemb_cc2|Predicted transmembrane and coiled-coil 2 protein|ENSGALT00000090409|m.1078:36-428
ENSGALG00000011322	3.529504919	1.490716699	1.237895926	1.43E-18	1.23E-17	up	yes	3.534985	3.471096604	3.582433153	1.415970004	1.744498976	1.311681116	2	38299506	38378275	-	NEK10	protein_coding	GO:0006468|protein phosphorylation; GO:0031954|positive regulation of protein autophosphorylation; GO:0043406|positive regulation of MAP kinase activity; GO:0070372|regulation of ERK1 and ERK2 cascade; GO:1902749|regulation of cell cycle G2/M phase transition	GO:1902911|protein kinase complex	GO:0004672|protein kinase activity; GO:0004674|protein serine/threonine kinase activity; GO:0005524|ATP binding; GO:0046872|metal ion binding	ko:K20879|NEK10	--	3662	XP_015137277.2	XP_015137277.2 serine/threonine-protein kinase Nek10 [Gallus gallus]	sp|Q6ZWH5|NEK10_HUMAN	sp|Q6ZWH5|NEK10_HUMAN Serine/threonine-protein kinase Nek10 OS=Homo sapiens GN=NEK10 PE=2 SV=3	9031.ENSGALP00000018451	annotation not avaliable	COG0515	KOG0589	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000099675|m.401:520-780;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000099675|m.401:522-783;PF01163.19|RIO1|RIO1 family|ENSGALT00000099675|m.401:602-683
ENSGALG00000011342	17.4488176	35.88071252	-1.039654708	8.06E-40	1.99E-38	down	yes	15.9347064	18.05035707	18.36138935	33.46582835	38.94621817	35.23009104	1	45405227	45469802	-	FGD6	protein_coding	GO:0007010|cytoskeleton organization; GO:0008360|regulation of cell shape; GO:0030036|actin cytoskeleton organization; GO:0035023|regulation of Rho protein signal transduction; GO:0043087|regulation of GTPase activity; GO:0046847|filopodium assembly	GO:0001726|ruffle; GO:0005737|cytoplasm; GO:0005794|Golgi apparatus; GO:0005856|cytoskeleton; GO:0030027|lamellipodium	GO:0005085|guanyl-nucleotide exchange factor activity; GO:0005089|Rho guanyl-nucleotide exchange factor activity; GO:0031267|small GTPase binding; GO:0046872|metal ion binding	ko:K05724|FGD5_6	--	4302	XP_015139476.1	"XP_015139476.1 FYVE, RhoGEF and PH domain-containing protein 6 [Gallus gallus]"	sp|Q6ZV73|FGD6_HUMAN	"sp|Q6ZV73|FGD6_HUMAN FYVE, RhoGEF and PH domain-containing protein 6 OS=Homo sapiens GN=FGD6 PE=1 SV=2"	9031.ENSGALP00000018485	"FYVE, RhoGEF and PH domain containing 6"	_	KOG1729	_	PF00621.17|RhoGEF|RhoGEF domain|ENSGALT00000018508|m.1087:878-1061;PF00169.26|PH|PH domain|ENSGALT00000018508|m.1087:1094-1185;PF00169.26|PH|PH domain|ENSGALT00000018508|m.1087:1339-1429;PF01363.18|FYVE|FYVE zinc finger|ENSGALT00000018508|m.1087:1221-1284
ENSGALG00000011349	5.757148852	12.64939941	-1.134278797	7.29E-14	4.46E-13	down	yes	5.225958792	5.800245795	6.24524197	13.6158704	12.30627608	12.02605175	7	22316359	22322097	+	ENSGALG00000011349	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006357|regulation of transcription by RNA polymerase II; GO:0006959|humoral immune response; GO:0009653|anatomical structure morphogenesis; GO:0021520|spinal cord motor neuron cell fate specification; GO:0031018|endocrine pancreas development; GO:0048812|neuron projection morphogenesis"	GO:0005634|nucleus; GO:0005730|nucleolus; GO:0005829|cytosol	GO:0003700|DNA-binding transcription factor activity; GO:0043565|sequence-specific DNA binding	"ko:K08025|HLXB9,HB9"	ko04950|Maturity onset diabetes of the young	1099	XP_015145563.1	XP_015145563.1 motor neuron and pancreas homeobox protein 1 [Gallus gallus]	sp|P50219|MNX1_HUMAN	sp|P50219|MNX1_HUMAN Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens GN=MNX1 PE=1 SV=3	_	_	_	_	_	PF00046.26|Homeobox|Homeobox domain|ENSGALT00000018518|m.6407:154-210
ENSGALG00000011353	0.408588361	2.384141473	-2.515904303	1.54E-24	1.87E-23	down	yes	0.571747969	0.275793492	0.378223622	2.280788708	2.279094231	2.592541478	8	29915375	29960430	+	TNNI3K	protein_coding	GO:0002027|regulation of heart rate; GO:0006468|protein phosphorylation; GO:0035556|intracellular signal transduction; GO:0055117|regulation of cardiac muscle contraction; GO:0086069|bundle of His cell to Purkinje myocyte communication; GO:1903779|regulation of cardiac conduction	GO:0005634|nucleus; GO:0005737|cytoplasm	GO:0004672|protein kinase activity; GO:0004674|protein serine/threonine kinase activity; GO:0005524|ATP binding; GO:0008022|protein C-terminus binding; GO:0031013|troponin I binding; GO:0046872|metal ion binding	ko:K17535|TNNI3K	--	3502	NP_001191745.1	NP_001191745.1 serine/threonine-protein kinase TNNI3K [Gallus gallus]	sp|Q59H18|TNI3K_HUMAN	sp|Q59H18|TNI3K_HUMAN Serine/threonine-protein kinase TNNI3K OS=Homo sapiens GN=TNNI3K PE=1 SV=3	_	_	_	_	_	PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000018524|m.8219:463-719;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000018524|m.8219:57-129;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000018524|m.8219:135-195;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000018524|m.8219:169-232;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000018524|m.8219:204-291;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000018524|m.8219:274-368;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000018524|m.8219:100-130;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000018524|m.8219:136-164;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000018524|m.8219:168-195;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000018524|m.8219:202-233;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000018524|m.8219:269-291;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000018524|m.8219:339-369;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000018524|m.8219:68-121;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000018524|m.8219:135-187;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000018524|m.8219:169-219;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000018524|m.8219:224-255;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000018524|m.8219:238-287;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000018524|m.8219:307-360;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000018524|m.8219:344-394;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000018524|m.8219:464-716;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000018524|m.8219:169-195;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000018524|m.8219:269-291;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000018524|m.8219:339-365
ENSGALG00000011389	14.91349189	46.51049971	-1.640281448	3.33E-90	3.38E-88	down	yes	15.72518027	13.81845046	15.19684494	45.95158946	49.23419254	44.34571711	5	50027923	50071113	+	TRAF3	protein_coding	GO:0001817|regulation of cytokine production; GO:0002224|toll-like receptor signaling pathway; GO:0006915|apoptotic process; GO:0008063|Toll signaling pathway; GO:0030162|regulation of proteolysis; GO:0032088|negative regulation of NF-kappaB transcription factor activity; GO:0032648|regulation of interferon-beta production; GO:0033209|tumor necrosis factor-mediated signaling pathway; GO:0042981|regulation of apoptotic process; GO:0045087|innate immune response; GO:0050688|regulation of defense response to virus	GO:0005768|endosome; GO:0009898|cytoplasmic side of plasma membrane; GO:0035631|CD40 receptor complex	GO:0005164|tumor necrosis factor receptor binding; GO:0008270|zinc ion binding; GO:0016740|transferase activity; GO:0019901|protein kinase binding; GO:0019903|protein phosphatase binding; GO:0031625|ubiquitin protein ligase binding; GO:0031996|thioesterase binding	ko:K03174|TRAF3	ko04064|NF-kappa B signaling pathway; ko04620|Toll-like receptor signaling pathway; ko04621|NOD-like receptor signaling pathway; ko04622|RIG-I-like receptor signaling pathway; ko04657|IL-17 signaling pathway; ko04668|TNF signaling pathway; ko05160|Hepatitis C; ko05168|Herpes simplex infection; ko05169|Epstein-Barr virus infection; ko05200|Pathways in cancer; ko05203|Viral carcinogenesis; ko05222|Small cell lung cancer	2103	XP_004936398.1	XP_004936398.1 TNF receptor-associated factor 3 isoform X1 [Gallus gallus]	sp|Q60803|TRAF3_MOUSE	sp|Q60803|TRAF3_MOUSE TNF receptor-associated factor 3 OS=Mus musculus GN=Traf3 PE=1 SV=2	_	_	_	_	_	PF02176.15|zf-TRAF|TRAF-type zinc finger|ENSGALT00000097128|m.3888:135-191;PF02176.15|zf-TRAF|TRAF-type zinc finger|ENSGALT00000097128|m.3888:191-250
ENSGALG00000011406	0.164047184	0.63531666	-1.890528801	0.001253374	0.002604388	down	yes	0.1120491	0.102693121	0.27739933	0.558448622	0.398835084	0.948666273	1	45630400	45665253	-	NTN4	protein_coding	GO:0016322|neuron remodeling; GO:0030198|extracellular matrix organization; GO:0060668|regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling	GO:0005604|basement membrane; GO:0005886|plasma membrane	GO:0043237|laminin-1 binding	ko:K06845|NTN4	ko04360|Axon guidance	1881	XP_015139402.1	XP_015139402.1 netrin-4 isoform X2 [Gallus gallus]	sp|Q9JI33|NET4_MOUSE	sp|Q9JI33|NET4_MOUSE Netrin-4 OS=Mus musculus GN=Ntn4 PE=1 SV=2	9031.ENSGALP00000018590	netrin 4	_	KOG0994	_	PF00055.14|Laminin_N|Laminin N-terminal (Domain VI)|ENSGALT00000018613|m.1092:34-258;PF00053.21|Laminin_EGF|Laminin EGF domain|ENSGALT00000018613|m.1092:260-316;PF00053.21|Laminin_EGF|Laminin EGF domain|ENSGALT00000018613|m.1092:330-381;PF00053.21|Laminin_EGF|Laminin EGF domain|ENSGALT00000018613|m.1092:393-444;PF01759.18|NTR|UNC-6/NTR/C345C module|ENSGALT00000018613|m.1092:517-618
ENSGALG00000011446	0.15672698	1.759883381	-3.408094814	0.000147534	0.000353139	down	yes	0.337330916	0.019786506	0.113063519	1.832239803	2.001197166	1.446213175	5	50330268	50347510	+	TNFAIP2	protein_coding	GO:0001525|angiogenesis; GO:0006887|exocytosis; GO:0030154|cell differentiation; GO:0051601|exocyst localization	GO:0000145|exocyst	GO:0000149|SNARE binding	"ko:K19989|TNFAIP2,EXOC3L3"	--	3905	XP_015143422.1	XP_015143422.1 tumor necrosis factor alpha-induced protein 2 [Gallus gallus]	sp|Q61333|TNAP2_MOUSE	sp|Q61333|TNAP2_MOUSE Tumor necrosis factor alpha-induced protein 2 OS=Mus musculus GN=Tnfaip2 PE=1 SV=2	_	_	_	_	_	PF06046.10|Sec6|Exocyst complex component Sec6|ENSGALT00000018666|m.3898:164-698
ENSGALG00000011447	3.015966682	6.950344939	-1.201762702	4.11E-10	1.85E-09	down	yes	2.847239841	2.490027394	3.71063281	6.516228607	6.240886231	8.093919979	2	39825774	39907578	-	GADL1	protein_coding	GO:0008652|cellular amino acid biosynthetic process	GO:0005829|cytosol	GO:0004068|aspartate 1-decarboxylase activity; GO:0004782|sulfinoalanine decarboxylase activity; GO:0016831|carboxy-lyase activity; GO:0030170|pyridoxal phosphate binding	"ko:K18966|GADL1,CSADC,ADC"	ko00410|beta-Alanine metabolism; ko00430|Taurine and hypotaurine metabolism; ko00770|Pantothenate and CoA biosynthesis; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites	1536	XP_004939481.1	XP_004939481.1 acidic amino acid decarboxylase GADL1 isoform X1 [Gallus gallus]	sp|Q6ZQY3|GADL1_HUMAN	sp|Q6ZQY3|GADL1_HUMAN Acidic amino acid decarboxylase GADL1 OS=Homo sapiens GN=GADL1 PE=1 SV=4	_	_	_	_	_	PF00282.16|Pyridoxal_deC|Pyridoxal-dependent decarboxylase conserved domain|ENSGALT00000018667|m.425:67-434;PF00266.16|Aminotran_5|Aminotransferase class-V|ENSGALT00000018667|m.425:222-293
ENSGALG00000011468	1.182946831	5.147350861	-2.112100453	2.54E-12	1.37E-11	down	yes	1.170913091	1.287771743	1.090155659	5.016086209	4.785282428	5.640683945	7	23232312	23248990	+	IGFBP5	protein_coding	GO:0001558|regulation of cell growth; GO:0043567|regulation of insulin-like growth factor receptor signaling pathway; GO:0060416|response to growth hormone	GO:0005615|extracellular space	GO:0001968|fibronectin binding; GO:0031994|insulin-like growth factor I binding; GO:0031995|insulin-like growth factor II binding	--	--	810	XP_011579367.1	XP_011579367.1 PREDICTED: insulin-like growth factor-binding protein 5 [Aquila chrysaetos canadensis]	sp|Q28985|IBP5_PIG	sp|Q28985|IBP5_PIG Insulin-like growth factor-binding protein 5 OS=Sus scrofa GN=IGFBP5 PE=2 SV=2	_	_	_	_	_	PF00086.15|Thyroglobulin_1|Thyroglobulin type-1 repeat|ENSGALT00000038163|m.6469:189-260;PF00219.15|IGFBP|Insulin-like growth factor binding protein|ENSGALT00000038163|m.6469:25-78
ENSGALG00000011473	0.312948375	0.718364606	-1.173357256	0.003783646	0.007234973	down	yes	0.327855666	0.343405798	0.267583662	0.67827273	0.657590424	0.819230664	3	42691591	42928349	+	RPS6KA2	protein_coding	GO:0001556|oocyte maturation; GO:0002035|brain renin-angiotensin system; GO:0006468|protein phosphorylation; GO:0007507|heart development; GO:0008285|negative regulation of cell population proliferation; GO:0010628|positive regulation of gene expression; GO:0010659|cardiac muscle cell apoptotic process; GO:0018105|peptidyl-serine phosphorylation; GO:0035556|intracellular signal transduction; GO:0043065|positive regulation of apoptotic process; GO:0045786|negative regulation of cell cycle; GO:0045835|negative regulation of meiotic nuclear division; GO:0060047|heart contraction; GO:0070613|regulation of protein processing; GO:0071322|cellular response to carbohydrate stimulus	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005819|spindle	GO:0000287|magnesium ion binding; GO:0004672|protein kinase activity; GO:0004674|protein serine/threonine kinase activity; GO:0004711|ribosomal protein S6 kinase activity; GO:0004712|protein serine/threonine/tyrosine kinase activity; GO:0005524|ATP binding	"ko:K04373|RPS6KA,RSK2"	ko04010|MAPK signaling pathway; ko04114|Oocyte meiosis; ko04150|mTOR signaling pathway; ko04720|Long-term potentiation; ko04722|Neurotrophin signaling pathway; ko04914|Progesterone-mediated oocyte maturation; ko04931|Insulin resistance	2202	XP_010705389.1	XP_010705389.1 PREDICTED: ribosomal protein S6 kinase alpha-2 [Meleagris gallopavo]	sp|Q9WUT3|KS6A2_MOUSE	sp|Q9WUT3|KS6A2_MOUSE Ribosomal protein S6 kinase alpha-2 OS=Mus musculus GN=Rps6ka2 PE=1 SV=1	_	_	_	_	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000093334|m.11822:59-318;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000093334|m.11822:415-672;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000093334|m.11822:60-301;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000093334|m.11822:416-667;PF14531.3|Kinase-like|Kinase-like|ENSGALT00000093334|m.11822:172-297;PF06293.11|Kdo|Lipopolysaccharide kinase (Kdo/WaaP) family|ENSGALT00000093334|m.11822:483-555;PF00433.21|Pkinase_C|Protein kinase C terminal domain|ENSGALT00000093334|m.11822:342-378
ENSGALG00000011493	21.30301598	9.391920601	1.180707359	1.59E-22	1.73E-21	up	yes	20.62184585	21.78606784	21.50113424	8.207670013	10.77097157	9.19712022	7	23551701	23559373	-	TMEM169	protein_coding	--	GO:0016021|integral component of membrane	--	--	--	1275	XP_015145533.1	XP_015145533.1 transmembrane protein 169 [Gallus gallus]	sp|Q8BG50|TM169_MOUSE	sp|Q8BG50|TM169_MOUSE Transmembrane protein 169 OS=Mus musculus GN=Tmem169 PE=2 SV=1	9031.ENSGALP00000018707	transmembrane protein 169	_	_	NOG84759	PF15052.3|TMEM169|TMEM169 protein family|ENSGALT00000038136|m.6482:157-286
ENSGALG00000011511	0.510187364	1.777699516	-1.781001004	4.26E-09	1.74E-08	down	yes	0.37681351	0.675351093	0.478397488	2.204808962	1.523401073	1.604888515	5	50513973	50524885	-	CKB	protein_coding	GO:0006754|ATP biosynthetic process; GO:0021762|substantia nigra development	GO:0005615|extracellular space; GO:0005739|mitochondrion; GO:0005829|cytosol; GO:0043209|myelin sheath; GO:0065010|extracellular membrane-bounded organelle; GO:0070062|extracellular exosome	GO:0004111|creatine kinase activity; GO:0005524|ATP binding; GO:0031625|ubiquitin protein ligase binding	ko:K00933|E2.7.3.2	ko00330|Arginine and proline metabolism; ko01100|Metabolic pathways	1891	NP_990641.1	NP_990641.1 creatine kinase B-type [Gallus gallus]	sp|P05122|KCRB_CHICK	sp|P05122|KCRB_CHICK Creatine kinase B-type OS=Gallus gallus GN=CKB PE=1 SV=1	9031.ENSGALP00000018743	Creatine kinase B-type (EC 2.7.3.2)(Creatine kinase B chain)(B-CK); Reversibly catalyzes the [...] 	COG3869	KOG3581	_	"PF00217.16|ATP-gua_Ptrans|ATP:guanido phosphotransferase, C-terminal catalytic domain|ENSGALT00000087830|m.3912:52-297;PF02807.12|ATP-gua_PtransN|ATP:guanido phosphotransferase, N-terminal domain|ENSGALT00000087830|m.3912:1-30"
ENSGALG00000011529	0.528921409	1.136021305	-1.08848706	0.016939496	0.028530797	down	yes	0.680512221	0.498952151	0.407299854	1.18844811	1.134233262	1.085382543	4	49974752	49982898	-	NAAA	protein_coding	GO:0006629|lipid metabolic process; GO:0007269|neurotransmitter secretion	GO:0005737|cytoplasm; GO:0043202|lysosomal lumen; GO:0070062|extracellular exosome; GO:0098793|presynapse	"GO:0008134|transcription factor binding; GO:0016810|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"	ko:K13720|NAAA	--	1084	XP_015131911.1	XP_015131911.1 N-acylethanolamine-hydrolyzing acid amidase isoform X1 [Gallus gallus]	sp|Q02083|NAAA_HUMAN	sp|Q02083|NAAA_HUMAN N-acylethanolamine-hydrolyzing acid amidase OS=Homo sapiens GN=NAAA PE=1 SV=3	9031.ENSGALP00000037111	N-acylsphingosine amidohydrolase (acid ceramidase)-like	_	_	NOG77305	"PF15508.3|NAAA-beta|beta subunit of N-acylethanolamine-hydrolyzing acid amidase|ENSGALT00000037904|m.666:33-119;PF02275.15|CBAH|Linear amide C-N hydrolases, choloylglycine hydrolase family|ENSGALT00000037904|m.666:124-251"
ENSGALG00000011581	1.502182216	10.23861012	-2.760724371	1.29E-136	4.11E-134	down	yes	1.331543768	1.74669401	1.42830887	9.652585572	10.35687364	10.70637114	5	50931834	50997535	+	KIF26A	protein_coding	GO:0001560|regulation of cell growth by extracellular stimulus; GO:0009968|negative regulation of signal transduction; GO:0048484|enteric nervous system development	GO:0005737|cytoplasm; GO:0005871|kinesin complex; GO:0005874|microtubule	GO:0005524|ATP binding; GO:0008017|microtubule binding	ko:K10404|KIF26	--	5817	XP_421394.4	XP_421394.4 kinesin-like protein KIF26A [Gallus gallus]	sp|Q52KG5|KI26A_MOUSE	sp|Q52KG5|KI26A_MOUSE Kinesin-like protein KIF26A OS=Mus musculus GN=Kif26a PE=1 SV=2	_	_	_	_	_	PF00225.20|Kinesin|Kinesin motor domain|ENSGALT00000018906|m.3944:333-634;PF16796.2|Microtub_bd|Microtubule binding|ENSGALT00000018906|m.3944:283-446
ENSGALG00000011592	2.713308033	9.462890231	-1.798444492	7.37E-41	1.96E-39	down	yes	2.52692612	3.465318279	2.147679701	9.592995958	9.378535281	9.417139455	7	25228579	25265411	+	MRAS	protein_coding	GO:0007265|Ras protein signal transduction; GO:0007275|multicellular organism development; GO:0007517|muscle organ development; GO:0030036|actin cytoskeleton organization; GO:1990830|cellular response to leukemia inhibitory factor	GO:0005622|intracellular; GO:0005886|plasma membrane; GO:0070062|extracellular exosome	GO:0003924|GTPase activity; GO:0005525|GTP binding; GO:0030742|GTP-dependent protein binding	ko:K07831|MRAS	ko04010|MAPK signaling pathway; ko04014|Ras signaling pathway; ko04015|Rap1 signaling pathway; ko04072|Phospholipase D signaling pathway; ko04137|Mitophagy - animal; ko04140|Autophagy - animal; ko04371|Apelin signaling pathway; ko04810|Regulation of actin cytoskeleton; ko05166|HTLV-I infection; ko05205|Proteoglycans in cancer	3659	XP_014436402.1	XP_014436402.1 ras-related protein M-Ras isoform X1 [Pelodiscus sinensis]	sp|O14807|RASM_HUMAN	sp|O14807|RASM_HUMAN Ras-related protein M-Ras OS=Homo sapiens GN=MRAS PE=1 SV=2	9031.ENSGALP00000018902	muscle RAS oncogene homolog 	COG1100	KOG0395	_	"PF00071.19|Ras|Ras family|ENSGALT00000094705|m.6498:15-176;PF08477.10|Roc|Ras of Complex, Roc, domain of DAPkinase|ENSGALT00000094705|m.6498:15-129;PF00009.24|GTP_EFTU|Elongation factor Tu GTP binding domain|ENSGALT00000094705|m.6498:53-146;PF00025.18|Arf|ADP-ribosylation factor family|ENSGALT00000094705|m.6498:14-133"
ENSGALG00000011614	0.088727969	0.78243352	-3.004759155	1.04E-08	4.09E-08	down	yes	0	0.197713164	0.068470743	0.797925489	0.746540082	0.802834989	1	47510012	47607135	+	ANO4	protein_coding	GO:0061589|calcium activated phosphatidylserine scrambling; GO:0061590|calcium activated phosphatidylcholine scrambling; GO:0061591|calcium activated galactosylceramide scrambling	GO:0005622|intracellular; GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0005229|intracellular calcium activated chloride channel activity; GO:0017128|phospholipid scramblase activity; GO:0046983|protein dimerization activity	"ko:K19499|ANO4,TMEM16D"	--	2682	XP_015145116.1	XP_015145116.1 anoctamin-4 isoform X3 [Gallus gallus]	sp|A6QLE6|ANO4_BOVIN	sp|A6QLE6|ANO4_BOVIN Anoctamin-4 OS=Bos taurus GN=ANO4 PE=2 SV=1	9031.ENSGALP00000018946	transmembrane protein 16D	_	KOG2514	_	"PF04547.9|Anoctamin|Calcium-activated chloride channel|ENSGALT00000018969|m.1132:288-858;PF16178.2|Anoct_dimer|Dimerisation domain of Ca+-activated chloride-channel, anoctamin|ENSGALT00000018969|m.1132:70-285"
ENSGALG00000011624	0.781165649	0.197783887	1.928896007	6.54E-05	0.000164845	up	yes	0.890986346	0.563165485	0.889345115	0.219576383	0.133662079	0.240113199	3	45677747	45688264	-	PNLDC1	protein_coding	"GO:0000184|nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0000289|nuclear-transcribed mRNA poly(A) tail shortening"	GO:0005783|endoplasmic reticulum; GO:0005789|endoplasmic reticulum membrane; GO:0016021|integral component of membrane	GO:0003723|RNA binding; GO:0004535|poly(A)-specific ribonuclease activity; GO:0046872|metal ion binding	--	--	1715	XP_004935630.1	XP_004935630.1 poly(A)-specific ribonuclease PNLDC1 isoform X3 [Gallus gallus]	sp|B2RXZ1|PNDC1_MOUSE	sp|B2RXZ1|PNDC1_MOUSE Poly(A)-specific ribonuclease PNLDC1 OS=Mus musculus GN=Pnldc1 PE=1 SV=1	9031.ENSGALP00000018968	poly(A)-specific ribonuclease (PARN)-like domain containing 1	_	KOG1990	_	PF04857.17|CAF1|CAF1 family ribonuclease|ENSGALT00000018991|m.11862:5-371
ENSGALG00000011630	0.117994391	0.327405669	-1.398403622	3.61E-05	9.45E-05	down	yes	0.154416406	0.092633108	0.10693366	0.337940081	0.29425178	0.350025147	7	25779538	25958144	+	GLI2	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0001501|skeletal system development; GO:0001649|osteoblast differentiation; GO:0001701|in utero embryonic development; GO:0001822|kidney development; GO:0002062|chondrocyte differentiation; GO:0002076|osteoblast development; GO:0007224|smoothened signaling pathway; GO:0007389|pattern specification process; GO:0007411|axon guidance; GO:0007418|ventral midline development; GO:0007442|hindgut morphogenesis; GO:0007507|heart development; GO:0008283|cell population proliferation; GO:0008589|regulation of smoothened signaling pathway; GO:0009612|response to mechanical stimulus; GO:0009913|epidermal cell differentiation; GO:0009952|anterior/posterior pattern specification; GO:0009954|proximal/distal pattern formation; GO:0021508|floor plate formation; GO:0021513|spinal cord dorsal/ventral patterning; GO:0021517|ventral spinal cord development; GO:0021696|cerebellar cortex morphogenesis; GO:0021775|smoothened signaling pathway involved in ventral spinal cord interneuron specification; GO:0021776|smoothened signaling pathway involved in spinal cord motor neuron cell fate specification; GO:0021938|smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation; GO:0021965|spinal cord ventral commissure morphogenesis; GO:0021983|pituitary gland development; GO:0030324|lung development; GO:0030879|mammary gland development; GO:0030902|hindbrain development; GO:0032331|negative regulation of chondrocyte differentiation; GO:0033089|positive regulation of T cell differentiation in thymus; GO:0035295|tube development; GO:0042475|odontogenesis of dentin-containing tooth; GO:0042733|embryonic digit morphogenesis; GO:0043066|negative regulation of apoptotic process; GO:0045666|positive regulation of neuron differentiation; GO:0045740|positive regulation of DNA replication; GO:0045893|positive regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0048566|embryonic digestive tract development; GO:0048589|developmental growth; GO:0048666|neuron development; GO:0048754|branching morphogenesis of an epithelial tube; GO:0060032|notochord regression; GO:0060513|prostatic bud formation; GO:0060603|mammary gland duct morphogenesis; GO:0060831|smoothened signaling pathway involved in dorsal/ventral neural tube patterning; GO:0071407|cellular response to organic cyclic compound; GO:0090103|cochlea morphogenesis; GO:0098586|cellular response to virus"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005730|nucleolus; GO:0005829|cytosol; GO:0005929|cilium; GO:0005930|axoneme; GO:0016020|membrane; GO:0016607|nuclear speck; GO:0031514|motile cilium; GO:0097542|ciliary tip; GO:0097546|ciliary base	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003700|DNA-binding transcription factor activity; GO:0008134|transcription factor binding; GO:0008270|zinc ion binding; GO:0043565|sequence-specific DNA binding; GO:1990841|promoter-specific chromatin binding"	ko:K16798|GLI2	ko04340|Hedgehog signaling pathway; ko04390|Hippo signaling pathway; ko05200|Pathways in cancer; ko05217|Basal cell carcinoma	7455	NP_001258830.1	NP_001258830.1 zinc finger protein GLI2 isoform 1 [Gallus gallus]	sp|P10070|GLI2_HUMAN	sp|P10070|GLI2_HUMAN Zinc finger protein GLI2 OS=Homo sapiens GN=GLI2 PE=1 SV=4	59729.ENSTGUP00000004751	Zinc finger protein GLI2 (Tax helper protein) [Taeniopygia guttata]	COG5048	KOG1721	_	_
ENSGALG00000011635	26.88961427	58.89632166	-1.130836983	6.20E-39	1.47E-37	down	yes	26.64073273	26.56705571	27.46105437	65.0662152	57.62866725	53.99408252	7	26038309	26066954	-	TFCP2L1	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0000902|cell morphogenesis; GO:0002070|epithelial cell maturation; GO:0006351|transcription, DNA-templated; GO:0006357|regulation of transcription by RNA polymerase II; GO:0006694|steroid biosynthetic process; GO:0007028|cytoplasm organization; GO:0007431|salivary gland development; GO:0007565|female pregnancy; GO:0008340|determination of adult lifespan; GO:0045927|positive regulation of growth"	GO:0001650|fibrillar center; GO:0005634|nucleus; GO:0005739|mitochondrion; GO:0016020|membrane	GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding; GO:0003700|DNA-binding transcription factor activity; GO:0003714|transcription corepressor activity; GO:0043565|sequence-specific DNA binding	ko:K09275|TFCP2	--	1428	XP_015724314.1	XP_015724314.1 PREDICTED: transcription factor CP2-like protein 1 [Coturnix japonica]	sp|Q9NZI6|TF2L1_HUMAN	sp|Q9NZI6|TF2L1_HUMAN Transcription factor CP2-like protein 1 OS=Homo sapiens GN=TFCP2L1 PE=1 SV=1	9031.ENSGALP00000018984	transcription factor CP2-like 1	_	KOG4091	_	PF04516.12|CP2|CP2 transcription factor|ENSGALT00000029195|m.6526:34-238
ENSGALG00000011655	2.69897171	6.314812961	-1.223277489	2.29E-12	1.24E-11	down	yes	2.028380688	3.180342416	2.888192026	5.663597774	7.886411659	5.394429449	7	26299421	26318288	-	IQCB1	protein_coding	GO:0045494|photoreceptor cell maintenance; GO:0048496|maintenance of animal organ identity; GO:0060271|cilium assembly	GO:0001750|photoreceptor outer segment; GO:0005737|cytoplasm; GO:0005813|centrosome; GO:0032391|photoreceptor connecting cilium; GO:0070062|extracellular exosome	GO:0005516|calmodulin binding; GO:0019899|enzyme binding	"ko:K16774|IQCB1,NPHP5"	--	3377	XP_422091.4	XP_422091.4 IQ calmodulin-binding motif-containing protein 1 isoform X1 [Gallus gallus]	sp|Q8BP00|IQCB1_MOUSE	sp|Q8BP00|IQCB1_MOUSE IQ calmodulin-binding motif-containing protein 1 OS=Mus musculus GN=Iqcb1 PE=1 SV=2	9031.ENSGALP00000019025	IQ motif containing B1	_	KOG0160	_	PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000019048|m.6540:295-315;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000019048|m.6540:389-408
ENSGALG00000011663	0.156997294	0.472429534	-1.530493503	5.65E-05	0.000143417	down	yes	0.117877157	0.155569741	0.197544985	0.434524934	0.522143828	0.46061984	3	45891575	45929214	-	FNDC1	protein_coding	--	GO:0005576|extracellular region; GO:0016607|nuclear speck	--	--	--	4470	XP_015139799.1	XP_015139799.1 fibronectin type III domain-containing protein 1 [Gallus gallus]	sp|Q4ZHG4|FNDC1_HUMAN	sp|Q4ZHG4|FNDC1_HUMAN Fibronectin type III domain-containing protein 1 OS=Homo sapiens GN=FNDC1 PE=2 SV=4	9031.ENSGALP00000019042	fibronectin type III domain containing 1	_	KOG4221	_	PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000019065|m.11873:144-227;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000019065|m.11873:241-327;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000019065|m.11873:1253-1335
ENSGALG00000011668	2.268565777	46.89523535	-4.363551035	6.88E-10	3.01E-09	down	yes	4.678853541	1.002773079	1.12407071	50.84879394	43.14440751	46.6925046	4	50925077	50928369	+	IL8L1	protein_coding	GO:0001525|angiogenesis; GO:0002232|leukocyte chemotaxis involved in inflammatory response; GO:0002269|leukocyte activation involved in inflammatory response; GO:0002548|monocyte chemotaxis; GO:0006955|immune response; GO:0007186|G protein-coupled receptor signaling pathway; GO:0010628|positive regulation of gene expression; GO:0030097|hemopoiesis; GO:0030593|neutrophil chemotaxis; GO:0030595|leukocyte chemotaxis; GO:0032496|response to lipopolysaccharide; GO:0036446|myofibroblast differentiation; GO:0042060|wound healing; GO:0042119|neutrophil activation; GO:0048147|negative regulation of fibroblast proliferation; GO:0048246|macrophage chemotaxis; GO:0048247|lymphocyte chemotaxis; GO:0050729|positive regulation of inflammatory response; GO:0070098|chemokine-mediated signaling pathway; GO:0090023|positive regulation of neutrophil chemotaxis	GO:0005615|extracellular space	GO:0005125|cytokine activity; GO:0005153|interleukin-8 receptor binding; GO:0008009|chemokine activity; GO:0008083|growth factor activity; GO:0045236|CXCR chemokine receptor binding	"ko:K10030|IL8,CXCL8"	ko04060|Cytokine-cytokine receptor interaction; ko04062|Chemokine signaling pathway; ko04064|NF-kappa B signaling pathway; ko04072|Phospholipase D signaling pathway; ko04620|Toll-like receptor signaling pathway; ko04621|NOD-like receptor signaling pathway; ko04622|RIG-I-like receptor signaling pathway; ko04657|IL-17 signaling pathway; ko04932|Non-alcoholic fatty liver disease (NAFLD); ko04933|AGE-RAGE signaling pathway in diabetic complications; ko05120|Epithelial cell signaling in Helicobacter pylori infection; ko05131|Shigellosis; ko05132|Salmonella infection; ko05133|Pertussis; ko05134|Legionellosis; ko05142|Chagas disease (American trypanosomiasis); ko05144|Malaria; ko05146|Amoebiasis; ko05160|Hepatitis C; ko05161|Hepatitis B; ko05164|Influenza A; ko05200|Pathways in cancer; ko05202|Transcriptional misregulation in cancer; ko05219|Bladder cancer; ko05323|Rheumatoid arthritis	1464	NP_990349.1	NP_990349.1 interleukin-8 precursor [Gallus gallus]	sp|P08317|IL8_CHICK	sp|P08317|IL8_CHICK Interleukin-8 OS=Gallus gallus GN=CXCL8 PE=2 SV=1	9031.ENSGALP00000019049	K60 protein 	_	_	NOG73311	"PF00048.17|IL8|Small cytokines (intecrine/chemokine), interleukin-8 like|ENSGALT00000019072|m.707:33-91"
ENSGALG00000011671	0.690297167	2.130100838	-1.611639619	3.74E-08	1.40E-07	down	yes	0.763638973	0.507410062	0.799842467	1.920926969	2.746461842	1.722913703	7	26391057	26427532	+	SLC15A2	protein_coding	GO:0015031|protein transport	GO:0016021|integral component of membrane	GO:0015293|symporter activity; GO:0035673|oligopeptide transmembrane transporter activity	"ko:K14637|SLC15A2,PEPT2"	--	2208	NP_001305957.1	NP_001305957.1 solute carrier family 15 member 2 [Gallus gallus]	sp|P46029|S15A2_RABIT	sp|P46029|S15A2_RABIT Solute carrier family 15 member 2 OS=Oryctolagus cuniculus GN=SLC15A2 PE=2 SV=1	9031.ENSGALP00000019052	"solute carrier family 15 (H+/peptide transporter), member 2"	COG3104	KOG1237	_	PF00854.18|PTR2|POT family|ENSGALT00000019075|m.6543:120-449;PF00854.18|PTR2|POT family|ENSGALT00000019075|m.6543:609-671
ENSGALG00000011680	1.551143859	5.197967091	-1.738116845	1.40E-24	1.71E-23	down	yes	1.78634458	1.015724023	1.851362974	5.092043054	5.147304338	5.354553881	4	51053219	51252071	-	EPHA5	protein_coding	GO:0007411|axon guidance; GO:0021766|hippocampus development; GO:0032956|regulation of actin cytoskeleton organization; GO:0043087|regulation of GTPase activity; GO:0048013|ephrin receptor signaling pathway	GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0030424|axon; GO:0030425|dendrite	GO:0005004|GPI-linked ephrin receptor activity; GO:0005524|ATP binding	"ko:K05106|EPHA5,EHK1,TYRO4"	ko04360|Axon guidance	4125	NP_990436.2	NP_990436.2 ephrin type-A receptor 5 precursor [Gallus gallus]	sp|P54755|EPHA5_CHICK	sp|P54755|EPHA5_CHICK Ephrin type-A receptor 5 OS=Gallus gallus GN=EPHA5 PE=2 SV=1	9031.ENSGALP00000019068	Ephrin type-A receptor 5 Precursor (EC 2.7.10.1)(Tyrosine-protein kinase receptor CEK7); Rec [...] 	COG0515	KOG0196	_	PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000019091|m.715:680-936;PF01404.16|Ephrin_lbd|Ephrin receptor ligand binding domain|ENSGALT00000019091|m.715:66-237;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000019091|m.715:681-934;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000019091|m.715:368-452;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000019091|m.715:475-556;PF14575.3|EphA2_TM|Ephrin type-A receptor 2 transmembrane domain|ENSGALT00000019091|m.715:578-676;PF00536.27|SAM_1|SAM domain (Sterile alpha motif)|ENSGALT00000019091|m.715:971-1031;PF07647.14|SAM_2|SAM domain (Sterile alpha motif)|ENSGALT00000019091|m.715:973-1031
ENSGALG00000011687	4.890566172	1.75829609	1.470588571	4.78E-42	1.32E-40	up	yes	4.94127794	5.243818954	4.486601621	1.981070034	1.82711291	1.466705326	5	52000607	52016763	-	ENSGALG00000011687	protein_coding	--	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0030018|Z disc; GO:0030315|T-tubule; GO:0030659|cytoplasmic vesicle membrane; GO:0042383|sarcolemma; GO:0043034|costamere	--	--	--	13276	XP_025006644.1	XP_025006644.1 protein AHNAK2 isoform X1 [Gallus gallus]	sp|Q8IVF2|AHNK2_HUMAN	sp|Q8IVF2|AHNK2_HUMAN Protein AHNAK2 OS=Homo sapiens GN=AHNAK2 PE=1 SV=2	9031.ENSGALP00000019027	annotation not avaliable	_	_	NOG137551	_
ENSGALG00000011692	18.21762512	7.743594017	1.233189503	8.93E-40	2.20E-38	up	yes	18.15800015	20.06537903	16.42949619	7.813268477	7.564797022	7.852716553	5	52134885	52142967	-	CDCA4	protein_coding	--	GO:0005654|nucleoplasm; GO:0005829|cytosol; GO:0005886|plasma membrane	--	--	--	2200	POI26925.1	POI26925.1 hypothetical protein CIB84_009325 [Bambusicola thoracicus]	sp|Q9BXL8|CDCA4_HUMAN	sp|Q9BXL8|CDCA4_HUMAN Cell division cycle-associated protein 4 OS=Homo sapiens GN=CDCA4 PE=1 SV=1	9031.ENSGALP00000036643	cell division cycle associated 4 	_	_	NOG42395	PF06031.10|SERTA|SERTA motif|ENSGALT00000019114|m.3969:52-87
ENSGALG00000011721	0.588890631	0.074332105	2.82813869	2.08E-06	6.40E-06	up	yes	0.706078246	0.388272887	0.672320758	0.055331261	0.058177368	0.109487686	5	53102807	53104597	-	ENSGALG00000011721	protein_coding	GO:0006605|protein targeting; GO:0007165|signal transduction; GO:0007268|chemical synaptic transmission; GO:0010739|positive regulation of protein kinase A signaling	GO:0005829|cytosol; GO:0005886|plasma membrane	GO:0005516|calmodulin binding; GO:0008179|adenylate cyclase binding; GO:0017124|SH3 domain binding; GO:0030346|protein phosphatase 2B binding; GO:0034237|protein kinase A regulatory subunit binding; GO:0035254|glutamate receptor binding; GO:0051018|protein kinase A binding; GO:0097110|scaffold protein binding	ko:K16522|AKAP5	--	1791	XP_015143367.1	XP_015143367.1 A-kinase anchor protein 5 [Gallus gallus]	sp|P24588|AKAP5_HUMAN	sp|P24588|AKAP5_HUMAN A-kinase anchor protein 5 OS=Homo sapiens GN=AKAP5 PE=1 SV=3	9031.ENSGALP00000019127	A kinase (PRKA) anchor protein 5	_	_	NOG25796	_
ENSGALG00000011740	2.554375151	0.64481871	1.969439885	3.98E-06	1.18E-05	up	yes	2.491650945	3.385102357	1.786372151	0.606442934	0.782554374	0.545458821	1	48028649	48034022	+	MGP	protein_coding	GO:0001503|ossification; GO:0030154|cell differentiation; GO:0051216|cartilage development	GO:0031012|extracellular matrix; GO:0070062|extracellular exosome	GO:0005201|extracellular matrix structural constituent; GO:0005509|calcium ion binding	ko:K19481|MGP	--	719	OXB75392.1	OXB75392.1 hypothetical protein H355_010594 [Colinus virginianus]	sp|O42413|MGP_CHICK	sp|O42413|MGP_CHICK Matrix Gla protein OS=Gallus gallus GN=MGP PE=2 SV=1	9031.ENSGALP00000019149	Matrix Gla protein Precursor (MGP); Associates with the organic matrix of bone and cartilage [...] 	_	_	NOG42431	_
ENSGALG00000011783	44.85292478	15.86975598	1.498334935	1.21E-41	3.29E-40	up	yes	43.04642138	45.75662721	45.75572575	17.87236966	14.64068305	15.09621524	1	48176543	48177285	-	HIST1H111R	protein_coding	GO:0006334|nucleosome assembly	GO:0000786|nucleosome; GO:0005634|nucleus	GO:0003677|DNA binding	ko:K11275|H1_5	--	743	NP_001075172.1	NP_001075172.1 histone H1.11R [Gallus gallus]	sp|P08288|H11R_CHICK	sp|P08288|H11R_CHICK Histone H1.11R OS=Gallus gallus PE=3 SV=2	9031.ENSGALP00000019205	Histone H1.11R ; Histones H1 are necessary for the condensation of nucleosome chains into hi [...] 	_	KOG4012	_	PF00538.16|Linker_histone|linker histone H1 and H5 family|ENSGALT00000019229|m.1217:47-117
ENSGALG00000011800	5.485098664	11.52163573	-1.069379879	3.44E-29	5.14E-28	down	yes	5.335638063	5.707170225	5.412487705	10.66557843	11.69306916	12.20625959	1	48265083	48286901	+	FAM234B	protein_coding	--	GO:0016021|integral component of membrane	--	--	--	3960	NP_001012830.1	NP_001012830.1 protein FAM234B [Gallus gallus]	sp|Q5F3L3|F234B_CHICK	sp|Q5F3L3|F234B_CHICK Protein FAM234B OS=Gallus gallus GN=FAM234B PE=2 SV=1	9031.ENSGALP00000019233	Uncharacterized protein KIAA1467 homolog 	_	_	NOG69883	_
ENSGALG00000011801	0.241402715	0.782094	-1.655671416	1.18E-05	3.29E-05	down	yes	0.345269245	0.25315171	0.125787191	0.892166928	0.878687096	0.575427976	5	53184725	53226447	+	ESR2	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0030520|intracellular estrogen receptor signaling pathway"	GO:0005634|nucleus	GO:0003700|DNA-binding transcription factor activity; GO:0005496|steroid binding; GO:0008270|zinc ion binding; GO:0030284|estrogen receptor activity; GO:0043565|sequence-specific DNA binding	"ko:K08551|ESR2,NR3A2"	ko01522|Endocrine resistance; ko04915|Estrogen signaling pathway; ko04917|Prolactin signaling pathway; ko05224|Breast cancer	3510	XP_015720954.1	XP_015720954.1 PREDICTED: estrogen receptor beta isoform X2 [Coturnix japonica]	sp|Q9PVE2|ESR2_STUVU	sp|Q9PVE2|ESR2_STUVU Estrogen receptor beta OS=Sturnus vulgaris GN=ESR2 PE=2 SV=1	_	_	_	_	_	"PF12497.5|ERbeta_N|Estrogen receptor beta|ENSGALT00000019259|m.3991:36-149;PF00105.15|zf-C4|Zinc finger, C4 type (two domains)|ENSGALT00000019259|m.3991:173-241;PF00104.27|Hormone_recep|Ligand-binding domain of nuclear hormone receptor|ENSGALT00000019259|m.3991:307-500"
ENSGALG00000011803	2.145053848	0.537081268	1.977896853	2.34E-10	1.08E-09	up	yes	2.62274031	1.472564101	2.339857132	0.337734077	0.570039068	0.703470659	1	48327303	48341580	+	EMP1	protein_coding	GO:0007275|multicellular organism development; GO:0008219|cell death; GO:0008283|cell population proliferation; GO:0008544|epidermis development; GO:0016049|cell growth; GO:0032060|bleb assembly	GO:0005886|plasma membrane; GO:0016020|membrane; GO:0016021|integral component of membrane	--	--	--	2230	NP_001264299.1	NP_001264299.1 epithelial membrane protein 1 [Gallus gallus]	sp|P54849|EMP1_HUMAN	sp|P54849|EMP1_HUMAN Epithelial membrane protein 1 OS=Homo sapiens GN=EMP1 PE=1 SV=3	9031.ENSGALP00000029983	epithelial membrane protein 1	_	_	NOG45937	PF00822.17|PMP22_Claudin|PMP-22/EMP/MP20/Claudin family|ENSGALT00000030620|m.1232:1-159
ENSGALG00000011811	25.38591983	58.17724887	-1.196106307	1.39E-84	1.25E-82	down	yes	24.17121485	26.36170499	25.62483966	56.25454642	62.43299432	55.84420588	5	53231805	53388473	-	SYNE2	protein_coding	GO:0006998|nuclear envelope organization; GO:0007097|nuclear migration; GO:0007163|establishment or maintenance of cell polarity; GO:0010761|fibroblast migration; GO:0021817|nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration; GO:0030335|positive regulation of cell migration; GO:0031022|nuclear migration along microfilament; GO:0034504|protein localization to nucleus; GO:0051642|centrosome localization; GO:0090286|cytoskeletal anchoring at nuclear membrane; GO:1902017|regulation of cilium assembly	GO:0005634|nucleus; GO:0005635|nuclear envelope; GO:0005640|nuclear outer membrane; GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005739|mitochondrion; GO:0005925|focal adhesion; GO:0016021|integral component of membrane; GO:0016235|aggresome; GO:0016529|sarcoplasmic reticulum; GO:0030018|Z disc; GO:0031258|lamellipodium membrane; GO:0031527|filopodium membrane; GO:0031965|nuclear membrane; GO:0031981|nuclear lumen; GO:0033017|sarcoplasmic reticulum membrane; GO:0034993|meiotic nuclear membrane microtubule tethering complex; GO:0045111|intermediate filament cytoskeleton; GO:0070062|extracellular exosome	GO:0003779|actin binding; GO:0051015|actin filament binding	ko:K19346|SYNE2	--	20986	XP_015143371.1	XP_015143371.1 nesprin-2 isoform X4 [Gallus gallus]	sp|Q8WXH0|SYNE2_HUMAN	sp|Q8WXH0|SYNE2_HUMAN Nesprin-2 OS=Homo sapiens GN=SYNE2 PE=1 SV=3	9031.ENSGALP00000019252	annotation not avaliable	COG5069	KOG0516	_	PF00307.28|CH|Calponin homology (CH) domain|ENSGALT00000019277|m.3994:32-136;PF00307.28|CH|Calponin homology (CH) domain|ENSGALT00000019277|m.3994:183-285;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000019277|m.3994:1990-2088;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000019277|m.3994:6196-6297;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000019277|m.3994:6643-6748;PF10541.6|KASH|Nuclear envelope localisation domain|ENSGALT00000019277|m.3994:6925-6982
ENSGALG00000011838	4.314671469	14.03654513	-1.699552885	2.60E-66	1.53E-64	down	yes	4.206775365	4.572609824	4.164629219	14.05046874	14.46244904	13.59671761	1	48945372	48990389	-	GUCY2C	protein_coding	GO:0006182|cGMP biosynthetic process; GO:0007165|signal transduction; GO:0035556|intracellular signal transduction	"GO:0005789|endoplasmic reticulum membrane; GO:0005886|plasma membrane; GO:0008074|guanylate cyclase complex, soluble; GO:0016021|integral component of membrane"	GO:0004383|guanylate cyclase activity; GO:0004672|protein kinase activity; GO:0005524|ATP binding; GO:0005525|GTP binding	ko:K12320|GUCY2C	ko00230|Purine metabolism	3219	XP_416207.3	XP_416207.3 heat-stable enterotoxin receptor isoform X1 [Gallus gallus]	sp|P55204|GUC2C_PIG	sp|P55204|GUC2C_PIG Heat-stable enterotoxin receptor OS=Sus scrofa GN=GUCY2C PE=2 SV=2	9031.ENSGALP00000019294	guanylate cyclase 2C (heat stable enterotoxin receptor)	COG0515;COG2114	KOG1023	_	PF00211.17|Guanylate_cyc|Adenylate and Guanylate cyclase catalytic domain|ENSGALT00000019319|m.1238:817-1000;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000019319|m.1238:505-743;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000019319|m.1238:508-740;PF01094.25|ANF_receptor|Receptor family ligand binding region|ENSGALT00000019319|m.1238:115-379
ENSGALG00000011889	1.516689677	3.601002058	-1.241992401	1.07E-11	5.46E-11	down	yes	1.536446852	1.815691892	1.197930287	3.678365289	3.545869655	3.57877123	5	54228533	54333650	-	ENSGALG00000011889	protein_coding	GO:0006468|protein phosphorylation; GO:0007165|signal transduction; GO:0010744|positive regulation of macrophage derived foam cell differentiation; GO:0018105|peptidyl-serine phosphorylation; GO:0030168|platelet activation; GO:0034351|negative regulation of glial cell apoptotic process; GO:0035556|intracellular signal transduction; GO:0045618|positive regulation of keratinocyte differentiation; GO:0050861|positive regulation of B cell receptor signaling pathway; GO:0051092|positive regulation of NF-kappaB transcription factor activity; GO:0060252|positive regulation of glial cell proliferation; GO:0070528|protein kinase C signaling; GO:1903078|positive regulation of protein localization to plasma membrane; GO:2000810|regulation of bicellular tight junction assembly	GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0005911|cell-cell junction; GO:0070062|extracellular exosome	GO:0004697|protein kinase C activity; GO:0004699|calcium-independent protein kinase C activity; GO:0005524|ATP binding; GO:0017160|Ral GTPase binding; GO:0019899|enzyme binding; GO:0046872|metal ion binding	ko:K18051|PRKCH	ko04270|Vascular smooth muscle contraction; ko04750|Inflammatory mediator regulation of TRP channels	2915	XP_421417.4	XP_421417.4 protein kinase C eta type isoform X1 [Gallus gallus]	sp|P24723|KPCL_HUMAN	sp|P24723|KPCL_HUMAN Protein kinase C eta type OS=Homo sapiens GN=PRKCH PE=1 SV=4	9031.ENSGALP00000019373	"protein kinase C, eta"	COG0515	KOG0694	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000019399|m.4012:356-613;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000019399|m.4012:354-596;PF00130.19|C1_1|Phorbol esters/diacylglycerol binding domain (C1 domain)|ENSGALT00000019399|m.4012:171-224;PF00130.19|C1_1|Phorbol esters/diacylglycerol binding domain (C1 domain)|ENSGALT00000019399|m.4012:245-296;PF00168.27|C2|C2 domain|ENSGALT00000019399|m.4012:9-115;PF00433.21|Pkinase_C|Protein kinase C terminal domain|ENSGALT00000019399|m.4012:634-675
ENSGALG00000011894	6.032472314	38.39499571	-2.668083126	6.23E-111	1.03E-108	down	yes	5.035831425	6.827995645	6.233589873	35.09179732	45.80801722	34.2851726	1	49408394	49417609	+	CYP2D6	protein_coding	--	GO:0005789|endoplasmic reticulum membrane; GO:0031090|organelle membrane	"GO:0005506|iron ion binding; GO:0016712|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; GO:0020037|heme binding"	ko:K07414|CYP2D	ko00140|Steroid hormone biosynthesis; ko04726|Serotonergic synapse	2846	NP_001182486.1	NP_001182486.1 cytochrome P450 2D49 [Gallus gallus]	sp|Q9QYG5|CP2DK_MESAU	sp|Q9QYG5|CP2DK_MESAU Cytochrome P450 2D20 OS=Mesocricetus auratus GN=CYP2D20 PE=2 SV=1	9031.ENSGALP00000019386	similar to cytochrome P450 2D20	COG2124	KOG0156	_	PF00067.19|p450|Cytochrome P450|ENSGALT00000019412|m.1259:40-497
ENSGALG00000011962	2.256004164	5.042905101	-1.156962573	5.49E-10	2.43E-09	down	yes	1.551613354	2.836318563	2.380080574	4.892953011	4.959696878	5.276065413	4	54187801	54205828	+	NDNF	protein_coding	GO:0001525|angiogenesis; GO:0001764|neuron migration; GO:0002931|response to ischemia; GO:0007263|nitric oxide mediated signal transduction; GO:0010811|positive regulation of cell-substrate adhesion; GO:0010976|positive regulation of neuron projection development; GO:0016049|cell growth; GO:0019800|peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan; GO:0030198|extracellular matrix organization; GO:0043524|negative regulation of neuron apoptotic process; GO:0061042|vascular wound healing; GO:0071456|cellular response to hypoxia; GO:2000352|negative regulation of endothelial cell apoptotic process	GO:0005576|extracellular region; GO:0005622|intracellular; GO:0031012|extracellular matrix	GO:0005539|glycosaminoglycan binding; GO:0008201|heparin binding	--	--	2479	XP_015717402.1	XP_015717402.1 PREDICTED: protein NDNF isoform X1 [Coturnix japonica]	sp|Q8TB73|NDNF_HUMAN	sp|Q8TB73|NDNF_HUMAN Protein NDNF OS=Homo sapiens GN=NDNF PE=1 SV=2	_	_	_	_	_	PF10179.6|DUF2369|Uncharacterised conserved protein (DUF2369)|ENSGALT00000019508|m.787:166-260;PF10179.6|DUF2369|Uncharacterised conserved protein (DUF2369)|ENSGALT00000019508|m.787:329-608
ENSGALG00000011970	7.55576302	2.244307403	1.74680133	3.20E-40	8.11E-39	up	yes	7.263320269	7.055916009	8.348052782	2.15401141	2.134563986	2.444346812	1	49754389	49758184	+	CHADL	protein_coding	GO:0032331|negative regulation of chondrocyte differentiation; GO:1904027|negative regulation of collagen fibril organization	GO:0031012|extracellular matrix	GO:0005518|collagen binding; GO:0098633|collagen fibril binding	--	--	2880	XP_019470121.1	XP_019470121.1 PREDICTED: chondroadherin-like protein isoform X1 [Meleagris gallopavo]	sp|Q6NUI6|CHADL_HUMAN	sp|Q6NUI6|CHADL_HUMAN Chondroadherin-like protein OS=Homo sapiens GN=CHADL PE=1 SV=2	_	_	_	_	_	PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000019527|m.1311:54-111;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000019527|m.1311:75-135;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000019527|m.1311:101-159;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000019527|m.1311:124-183;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000019527|m.1311:148-207;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000019527|m.1311:172-231;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000019527|m.1311:195-251;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000019527|m.1311:243-300;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000019527|m.1311:403-459;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000019527|m.1311:424-482;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000019527|m.1311:471-531;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000019527|m.1311:545-587;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000019527|m.1311:68-157;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000019527|m.1311:157-265;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000019527|m.1311:414-505;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000019527|m.1311:485-614;PF00560.30|LRR_1|Leucine Rich Repeat|ENSGALT00000019527|m.1311:77-96;PF00560.30|LRR_1|Leucine Rich Repeat|ENSGALT00000019527|m.1311:448-469;PF01463.21|LRRCT|Leucine rich repeat C-terminal domain|ENSGALT00000019527|m.1311:323-345;PF01463.21|LRRCT|Leucine rich repeat C-terminal domain|ENSGALT00000019527|m.1311:673-686
ENSGALG00000011982	3.101088628	8.047954421	-1.37299415	3.46E-25	4.38E-24	down	yes	3.232910891	3.090652184	2.97970281	7.202262053	7.848229469	9.093371741	4	54643508	54703347	+	PDE5A	protein_coding	GO:0007165|signal transduction; GO:0010613|positive regulation of cardiac muscle hypertrophy; GO:0042130|negative regulation of T cell proliferation; GO:0043406|positive regulation of MAP kinase activity; GO:0046069|cGMP catabolic process; GO:0055118|negative regulation of cardiac muscle contraction; GO:0055119|relaxation of cardiac muscle; GO:0060282|positive regulation of oocyte development	GO:0005829|cytosol	"GO:0004114|3',5'-cyclic-nucleotide phosphodiesterase activity; GO:0030553|cGMP binding; GO:0046872|metal ion binding; GO:0047555|3',5'-cyclic-GMP phosphodiesterase activity"	ko:K13762|PDE5	ko00230|Purine metabolism; ko04022|cGMP-PKG signaling pathway	2649	XP_420631.3	"XP_420631.3 cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1 [Gallus gallus]"	sp|O76074|PDE5A_HUMAN	"sp|O76074|PDE5A_HUMAN cGMP-specific 3',5'-cyclic phosphodiesterase OS=Homo sapiens GN=PDE5A PE=1 SV=2"	9031.ENSGALP00000019524	"phosphodiesterase 5A, cGMP-specific"	_	KOG3689	_	PF00233.16|PDEase_I|3'5'-cyclic nucleotide phosphodiesterase|ENSGALT00000019550|m.793:593-814;PF01590.23|GAF|GAF domain|ENSGALT00000019550|m.793:146-286;PF01590.23|GAF|GAF domain|ENSGALT00000019550|m.793:328-482
ENSGALG00000011990	14.38161065	47.30698149	-1.717129981	2.10E-128	5.78E-126	down	yes	15.16565539	13.869935	14.10924156	45.05142802	50.32626255	46.54325391	4	54729233	54752851	-	USP53	protein_coding	GO:0001508|action potential; GO:0007605|sensory perception of sound; GO:0010996|response to auditory stimulus; GO:0016579|protein deubiquitination; GO:0051402|neuron apoptotic process	GO:0005923|bicellular tight junction	--	--	--	4270	XP_015717387.1	XP_015717387.1 PREDICTED: inactive ubiquitin carboxyl-terminal hydrolase 53 isoform X1 [Coturnix japonica]	sp|Q70EK8|UBP53_HUMAN	sp|Q70EK8|UBP53_HUMAN Inactive ubiquitin carboxyl-terminal hydrolase 53 OS=Homo sapiens GN=USP53 PE=1 SV=2	9031.ENSGALP00000019532	ubiquitin specific peptidase 53	_	KOG1887	_	PF00443.26|UCH|Ubiquitin carboxyl-terminal hydrolase|ENSGALT00000019558|m.797:39-348;PF13423.3|UCH_1|Ubiquitin carboxyl-terminal hydrolase|ENSGALT00000019558|m.797:39-321
ENSGALG00000012049	10.45295512	23.71627366	-1.181195156	0.000233756	0.000542229	down	yes	8.308317154	7.638253967	15.41229425	24.14306343	22.95879988	24.04695766	7	28037739	28054010	-	ZNF148	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006366|transcription by RNA polymerase II; GO:0006968|cellular defense response; GO:0007276|gamete generation; GO:0010629|negative regulation of gene expression; GO:0021762|substantia nigra development; GO:0045892|negative regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0065003|protein-containing complex assembly"	GO:0005634|nucleus; GO:0005794|Golgi apparatus	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0001227|DNA-binding transcription repressor activity, RNA polymerase II-specific; GO:0043565|sequence-specific DNA binding; GO:0046872|metal ion binding"	--	--	2325	XP_015145453.1	XP_015145453.1 zinc finger protein 148 isoform X1 [Gallus gallus]	sp|Q9UQR1|ZN148_HUMAN	sp|Q9UQR1|ZN148_HUMAN Zinc finger protein 148 OS=Homo sapiens GN=ZNF148 PE=1 SV=2	9031.ENSGALP00000019655	"solute carrier family 12 (potassium/chloride transporters), member 8"	COG5048	KOG1721	_	_
ENSGALG00000012061	2.339838288	10.36118474	-2.141947326	6.28E-57	2.78E-55	down	yes	1.970354357	2.132046704	2.917113804	10.71074385	10.63323682	9.739573548	7	28185901	28203831	+	ENSGALG00000012061	protein_coding	GO:0005975|carbohydrate metabolic process; GO:0046168|glycerol-3-phosphate catabolic process	GO:0009331|glycerol-3-phosphate dehydrogenase complex	GO:0004367|glycerol-3-phosphate dehydrogenase [NAD+] activity; GO:0042803|protein homodimerization activity; GO:0051287|NAD binding	ko:K00006|GPD1	ko00564|Glycerophospholipid metabolism; ko01110|Biosynthesis of secondary metabolites; ko04011|MAPK signaling pathway - yeast	3279	XP_422110.3	XP_422110.3 glycerol-3-phosphate dehydrogenase 1-like protein [Gallus gallus]	sp|Q6P824|GPD1L_XENTR	sp|Q6P824|GPD1L_XENTR Glycerol-3-phosphate dehydrogenase 1-like protein OS=Xenopus tropicalis GN=gpd1l PE=2 SV=1	9031.ENSGALP00000019678	glycerol-3-phosphate dehydrogenase 1 (soluble)	COG0240	KOG2711	_	PF01210.20|NAD_Gly3P_dh_N|NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus|ENSGALT00000095271|m.6610:6-172;PF07479.11|NAD_Gly3P_dh_C|NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus|ENSGALT00000095271|m.6610:193-339
ENSGALG00000012075	5.56081803	2.587918537	1.100532998	7.70E-15	5.08E-14	up	yes	5.004089687	5.358675295	6.319689107	2.278548589	2.636628843	2.848578178	7	28256073	28261454	-	DTX3L	protein_coding	"GO:0000209|protein polyubiquitination; GO:0002230|positive regulation of defense response to virus by host; GO:0006302|double-strand break repair; GO:0006511|ubiquitin-dependent protein catabolic process; GO:0006974|cellular response to DNA damage stimulus; GO:0008333|endosome to lysosome transport; GO:0010390|histone monoubiquitination; GO:0032092|positive regulation of protein binding; GO:0033522|histone H2A ubiquitination; GO:0033523|histone H2B ubiquitination; GO:0035563|positive regulation of chromatin binding; GO:0045893|positive regulation of transcription, DNA-templated; GO:0051444|negative regulation of ubiquitin-protein transferase activity; GO:0051865|protein autoubiquitination; GO:0070936|protein K48-linked ubiquitination; GO:1900182|positive regulation of protein localization to nucleus; GO:1901666|positive regulation of NAD+ ADP-ribosyltransferase activity; GO:1902966|positive regulation of protein localization to early endosome; GO:2000646|positive regulation of receptor catabolic process; GO:2001034|positive regulation of double-strand break repair via nonhomologous end joining"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005764|lysosome; GO:0005829|cytosol; GO:0032991|protein-containing complex	GO:0003723|RNA binding; GO:0004842|ubiquitin-protein transferase activity; GO:0004857|enzyme inhibitor activity; GO:0008047|enzyme activator activity; GO:0019899|enzyme binding; GO:0042393|histone binding; GO:0044389|ubiquitin-like protein ligase binding; GO:0046872|metal ion binding; GO:0097677|STAT family protein binding	ko:K06058|DTX	ko04330|Notch signaling pathway	3201	XP_422114.4	XP_422114.4 E3 ubiquitin-protein ligase DTX3L isoform X1 [Gallus gallus]	sp|Q8TDB6|DTX3L_HUMAN	sp|Q8TDB6|DTX3L_HUMAN E3 ubiquitin-protein ligase DTX3L OS=Homo sapiens GN=DTX3L PE=1 SV=1	9031.ENSGALP00000019701	deltex 3-like (Drosophila)	_	_	NOG84763	"PF13923.3|zf-C3HC4_2|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000019727|m.6620:560-598;PF13639.3|zf-RING_2|Ring finger domain|ENSGALT00000019727|m.6620:558-599;PF13920.3|zf-C3HC4_3|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000019727|m.6620:557-601;PF00097.22|zf-C3HC4|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000019727|m.6620:560-598;PF14634.3|zf-RING_5|zinc-RING finger domain|ENSGALT00000019727|m.6620:560-599;PF13445.3|zf-RING_UBOX|RING-type zinc-finger|ENSGALT00000019727|m.6620:560-596"
ENSGALG00000012076	0.222442301	1.001414257	-2.121429476	2.42E-06	7.38E-06	down	yes	0.251976515	0.287387955	0.127962431	0.979398601	1.118359431	0.906484741	4	57171233	57177054	+	TIFA	protein_coding	GO:0007249|I-kappaB kinase/NF-kappaB signaling	GO:0005622|intracellular	--	--	--	1882	XP_420645.2	XP_420645.2 TRAF-interacting protein with FHA domain-containing protein A isoform X2 [Gallus gallus]	sp|Q96CG3|TIFA_HUMAN	sp|Q96CG3|TIFA_HUMAN TRAF-interacting protein with FHA domain-containing protein A OS=Homo sapiens GN=TIFA PE=1 SV=1	9031.ENSGALP00000019702	TRAF-interacting protein with forkhead-associated domain	_	_	NOG46924	_
ENSGALG00000012087	6.262826983	13.50265441	-1.107123428	6.84E-24	8.01E-23	down	yes	5.906520964	6.189243922	6.692716062	13.67287923	13.95764453	12.87743948	7	28275428	28285479	+	CEP70	protein_coding	--	GO:0005737|cytoplasm; GO:0005815|microtubule organizing center	--	ko:K16802|CEP70	--	2141	XP_426601.2	XP_426601.2 centrosomal protein of 70 kDa [Gallus gallus]	sp|Q5RDE3|CEP70_PONAB	sp|Q5RDE3|CEP70_PONAB Centrosomal protein of 70 kDa OS=Pongo abelii GN=CEP70 PE=2 SV=1	9031.ENSGALP00000019716	centrosomal protein 70kDa	_	_	NOG68751	_
ENSGALG00000012089	4.307934527	1.446830992	1.567507849	1.06E-16	7.93E-16	up	yes	4.709106997	3.658018285	4.556678299	1.484080649	1.369141115	1.48727121	5	55503452	55514773	+	ENSGALG00000012089	protein_coding	--	--	--	--	--	2070	XP_004936522.2	XP_004936522.2 uncharacterized protein C14orf37 homolog isoform X1 [Gallus gallus]	_	_	9031.ENSGALP00000019719	chromosome 14 open reading frame 37	_	_	NOG84792	PF15767.2|DUF4696|Domain of unknown function (DUF4696)|ENSGALT00000019746|m.4073:34-598
ENSGALG00000012092	1.492065215	3.916195748	-1.386184652	1.42E-12	7.82E-12	down	yes	1.625031476	1.681121541	1.170042628	3.742875789	4.261149323	3.744562132	7	28286840	28313799	-	ESYT3	protein_coding	GO:0006687|glycosphingolipid metabolic process; GO:0006869|lipid transport	GO:0005789|endoplasmic reticulum membrane; GO:0005887|integral component of plasma membrane; GO:0031227|intrinsic component of endoplasmic reticulum membrane; GO:0031234|extrinsic component of cytoplasmic side of plasma membrane; GO:0044232|organelle membrane contact site	GO:0008289|lipid binding; GO:0046872|metal ion binding	--	--	2367	XP_422118.3	XP_422118.3 extended synaptotagmin-3 [Gallus gallus]	sp|A0FGR9|ESYT3_HUMAN	sp|A0FGR9|ESYT3_HUMAN Extended synaptotagmin-3 OS=Homo sapiens GN=ESYT3 PE=1 SV=1	_	_	_	_	_	PF17047.2|SMP_LBD|Synaptotagmin-like mitochondrial-lipid-binding domain|ENSGALT00000019750|m.6629:35-211;PF00168.27|C2|C2 domain|ENSGALT00000019750|m.6629:228-332;PF00168.27|C2|C2 domain|ENSGALT00000019750|m.6629:395-476;PF00168.27|C2|C2 domain|ENSGALT00000019750|m.6629:672-780
ENSGALG00000012100	0.005673003	0.427619194	-4.803322454	5.07E-06	1.48E-05	down	yes	0	0.01701901	0	0.454018591	0.431471039	0.397367953	7	28330072	28344049	-	CFAP221	protein_coding	GO:0003341|cilium movement; GO:0044458|motile cilium assembly; GO:0060271|cilium assembly	GO:0005737|cytoplasm; GO:0005929|cilium; GO:0005930|axoneme	GO:0005516|calmodulin binding	--	--	2270	XP_004943023.1	XP_004943023.1 cilia- and flagella-associated protein 221 [Gallus gallus]	sp|Q4G0U5|PCDP1_HUMAN	sp|Q4G0U5|PCDP1_HUMAN Cilia- and flagella-associated protein 221 OS=Homo sapiens GN=CFAP221 PE=1 SV=2	_	_	_	_	_	_
ENSGALG00000012123	3.937446046	13.14019979	-1.736093266	8.92E-64	4.90E-62	down	yes	4.037028717	3.741585562	4.033723857	13.50234724	12.89745355	13.02079858	5	5444151	5461448	-	PAX6	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated; GO:0007275|multicellular organism development"	GO:0005634|nucleus	GO:0043565|sequence-specific DNA binding	ko:K08031|PAX6	ko04550|Signaling pathways regulating pluripotency of stem cells; ko04950|Maturity onset diabetes of the young	2834	XP_013814720.1	XP_013814720.1 PREDICTED: paired box protein Pax-6 isoform X7 [Apteryx australis mantelli]	sp|P47238|PAX6_COTJA	sp|P47238|PAX6_COTJA Paired box protein Pax-6 OS=Coturnix japonica GN=PAX6 PE=2 SV=1	9823.ENSSSCP00000014151	paired box 6	_	KOG0849	_	PF00292.15|PAX|'Paired box' domain|ENSGALT00000019805|m.2336:82-206;PF00046.26|Homeobox|Homeobox domain|ENSGALT00000019805|m.2336:290-345
ENSGALG00000012136	15.62047335	36.84760076	-1.237600693	4.35E-44	1.28E-42	down	yes	15.53411368	16.28315826	15.0441481	37.02605683	36.24465529	37.27209014	5	4822409	4942957	-	MPPED2	protein_coding	GO:0007399|nervous system development	--	GO:0016787|hydrolase activity; GO:0046872|metal ion binding	--	--	1165	ERE72160.1	ERE72160.1 metallophosphoesterase MPPED2-like protein [Cricetulus griseus]	sp|Q15777|MPPD2_HUMAN	sp|Q15777|MPPD2_HUMAN Metallophosphoesterase MPPED2 OS=Homo sapiens GN=MPPED2 PE=1 SV=1	9796.ENSECAP00000017094	metallophosphoesterase domain containing 2	_	KOG3947	_	PF00149.25|Metallophos|Calcineurin-like phosphoesterase|ENSGALT00000101526|m.2316:59-255
ENSGALG00000012177	0.426364199	1.37223322	-1.663396411	3.66E-14	2.30E-13	down	yes	0.584655647	0.340587146	0.353849804	1.229126059	1.555253744	1.332319858	7	29785117	30106820	-	ENSGALG00000012177	protein_coding	--	--	--	--	--	6579	XP_025008410.1	XP_025008410.1 nck-associated protein 5 isoform X3 [Gallus gallus]	sp|O14513|NCKP5_HUMAN	sp|O14513|NCKP5_HUMAN Nck-associated protein 5 OS=Homo sapiens GN=NCKAP5 PE=1 SV=2	9031.ENSGALP00000019857	NCK-associated protein 5	_	_	NOG85857	"PF15246.3|NCKAP5|Nck-associated protein 5, Peripheral clock protein|ENSGALT00000019884|m.6661:1493-1779"
ENSGALG00000012178	0.375709184	1.650485289	-2.106019537	6.00E-08	2.19E-07	down	yes	0.369263697	0.541488927	0.216374929	1.805672319	1.179573575	1.966209972	1	50720146	50737226	+	PDGFB	protein_coding	"GO:0001568|blood vessel development; GO:0001892|embryonic placenta development; GO:0001938|positive regulation of endothelial cell proliferation; GO:0002548|monocyte chemotaxis; GO:0003104|positive regulation of glomerular filtration; GO:0006468|protein phosphorylation; GO:0006929|substrate-dependent cell migration; GO:0007179|transforming growth factor beta receptor signaling pathway; GO:0007416|synapse assembly; GO:0007507|heart development; GO:0007596|blood coagulation; GO:0008284|positive regulation of cell population proliferation; GO:0009611|response to wounding; GO:0010512|negative regulation of phosphatidylinositol biosynthetic process; GO:0010544|negative regulation of platelet activation; GO:0010628|positive regulation of gene expression; GO:0010629|negative regulation of gene expression; GO:0014068|positive regulation of phosphatidylinositol 3-kinase signaling; GO:0014911|positive regulation of smooth muscle cell migration; GO:0016322|neuron remodeling; GO:0018105|peptidyl-serine phosphorylation; GO:0018108|peptidyl-tyrosine phosphorylation; GO:0021782|glial cell development; GO:0030031|cell projection assembly; GO:0030036|actin cytoskeleton organization; GO:0030335|positive regulation of cell migration; GO:0030336|negative regulation of cell migration; GO:0031954|positive regulation of protein autophosphorylation; GO:0032091|negative regulation of protein binding; GO:0032147|activation of protein kinase activity; GO:0032148|activation of protein kinase B activity; GO:0035655|interleukin-18-mediated signaling pathway; GO:0035793|positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway; GO:0038001|paracrine signaling; GO:0038033|positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway; GO:0042462|eye photoreceptor cell development; GO:0043406|positive regulation of MAP kinase activity; GO:0043410|positive regulation of MAPK cascade; GO:0043536|positive regulation of blood vessel endothelial cell migration; GO:0043552|positive regulation of phosphatidylinositol 3-kinase activity; GO:0045737|positive regulation of cyclin-dependent protein serine/threonine kinase activity; GO:0045740|positive regulation of DNA replication; GO:0045743|positive regulation of fibroblast growth factor receptor signaling pathway; GO:0045840|positive regulation of mitotic nuclear division; GO:0045892|negative regulation of transcription, DNA-templated; GO:0045893|positive regulation of transcription, DNA-templated; GO:0045907|positive regulation of vasoconstriction; GO:0045977|positive regulation of mitotic cell cycle, embryonic; GO:0048008|platelet-derived growth factor receptor signaling pathway; GO:0048146|positive regulation of fibroblast proliferation; GO:0048514|blood vessel morphogenesis; GO:0048661|positive regulation of smooth muscle cell proliferation; GO:0050730|regulation of peptidyl-tyrosine phosphorylation; GO:0050731|positive regulation of peptidyl-tyrosine phosphorylation; GO:0050921|positive regulation of chemotaxis; GO:0051781|positive regulation of cell division; GO:0060041|retina development in camera-type eye; GO:0060326|cell chemotaxis; GO:0060445|branching involved in salivary gland morphogenesis; GO:0060664|epithelial cell proliferation involved in salivary gland morphogenesis; GO:0060947|cardiac vascular smooth muscle cell differentiation; GO:0061098|positive regulation of protein tyrosine kinase activity; GO:0061298|retina vasculature development in camera-type eye; GO:0070374|positive regulation of ERK1 and ERK2 cascade; GO:0070528|protein kinase C signaling; GO:0071363|cellular response to growth factor stimulus; GO:0071506|cellular response to mycophenolic acid; GO:0072126|positive regulation of glomerular mesangial cell proliferation; GO:0072255|metanephric glomerular mesangial cell development; GO:0072262|metanephric glomerular mesangial cell proliferation involved in metanephros development; GO:0072264|metanephric glomerular endothelium development; GO:0072593|reactive oxygen species metabolic process; GO:0090280|positive regulation of calcium ion import; GO:0097756|negative regulation of blood vessel diameter; GO:1900127|positive regulation of hyaluronan biosynthetic process; GO:1902894|negative regulation of pri-miRNA transcription by RNA polymerase II; GO:1902895|positive regulation of pri-miRNA transcription by RNA polymerase II; GO:1904707|positive regulation of vascular smooth muscle cell proliferation; GO:1904754|positive regulation of vascular associated smooth muscle cell migration; GO:1905064|negative regulation of vascular smooth muscle cell differentiation; GO:1905176|positive regulation of vascular smooth muscle cell dedifferentiation; GO:2000379|positive regulation of reactive oxygen species metabolic process; GO:2000573|positive regulation of DNA biosynthetic process; GO:2000591|positive regulation of metanephric mesenchymal cell migration"	GO:0005615|extracellular space; GO:0005737|cytoplasm; GO:0009986|cell surface; GO:0016323|basolateral plasma membrane; GO:0031012|extracellular matrix	GO:0005161|platelet-derived growth factor receptor binding; GO:0005518|collagen binding; GO:0008083|growth factor activity; GO:0016176|superoxide-generating NADPH oxidase activator activity; GO:0042056|chemoattractant activity; GO:0042802|identical protein binding; GO:0042803|protein homodimerization activity; GO:0046982|protein heterodimerization activity; GO:0048407|platelet-derived growth factor binding	ko:K17386|PDGFB	ko01521|EGFR tyrosine kinase inhibitor resistance; ko04010|MAPK signaling pathway; ko04014|Ras signaling pathway; ko04015|Rap1 signaling pathway; ko04060|Cytokine-cytokine receptor interaction; ko04072|Phospholipase D signaling pathway; ko04151|PI3K-Akt signaling pathway; ko04510|Focal adhesion; ko04540|Gap junction; ko04810|Regulation of actin cytoskeleton; ko05166|HTLV-I infection; ko05200|Pathways in cancer; ko05206|MicroRNAs in cancer; ko05211|Renal cell carcinoma; ko05214|Glioma; ko05215|Prostate cancer; ko05218|Melanoma; ko05231|Choline metabolism in cancer; ko05418|Fluid shear stress and atherosclerosis	1855	XP_015139855.2	XP_015139855.2 platelet-derived growth factor subunit B isoform X1 [Gallus gallus]	sp|P31240|PDGFB_MOUSE	sp|P31240|PDGFB_MOUSE Platelet-derived growth factor subunit B OS=Mus musculus GN=Pdgfb PE=2 SV=1	_	_	_	_	_	"PF00341.14|PDGF|PDGF/VEGF domain|ENSGALT00000019885|m.1352:104-187;PF04692.10|PDGF_N|Platelet-derived growth factor, N terminal region|ENSGALT00000019885|m.1352:30-100"
ENSGALG00000012197	0.36304985	1.330900013	-1.845761332	2.76E-05	7.35E-05	down	yes	0.493149142	0.278136446	0.317863961	1.05590689	1.680333271	1.256459878	7	30420994	30458182	+	ACMSD	protein_coding	GO:0051259|protein complex oligomerization; GO:1904985|negative regulation of quinolinate biosynthetic process	GO:0005829|cytosol; GO:0070062|extracellular exosome	GO:0001760|aminocarboxymuconate-semialdehyde decarboxylase activity; GO:0008270|zinc ion binding; GO:0016787|hydrolase activity; GO:0016831|carboxy-lyase activity	ko:K03392|ACMSD	ko00380|Tryptophan metabolism; ko01100|Metabolic pathways	1322	XP_422133.2	XP_422133.2 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase isoform X1 [Gallus gallus]	sp|Q0II68|ACMSD_BOVIN	sp|Q0II68|ACMSD_BOVIN 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase OS=Bos taurus GN=ACMSD PE=2 SV=1	9031.ENSGALP00000019890	aminocarboxymuconate semialdehyde decarboxylase	COG2159	KOG4245	_	PF04909.11|Amidohydro_2|Amidohydrolase|ENSGALT00000104747|m.6663:110-395
ENSGALG00000012230	3335.261661	1475.341609	1.176745453	3.45E-07	1.16E-06	up	yes	3515.103984	3337.929526	3152.751472	1068.346261	1485.808321	1871.870245	5	57738424	57745588	+	LRR1	protein_coding	GO:0007165|signal transduction; GO:0016567|protein ubiquitination; GO:0043687|post-translational protein modification	GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005886|plasma membrane	--	"ko:K10348|LRR1,PPIL5"	--	2763	XP_421455.3	XP_421455.3 leucine-rich repeat protein 1 isoform X1 [Gallus gallus]	sp|Q96L50|LLR1_HUMAN	sp|Q96L50|LLR1_HUMAN Leucine-rich repeat protein 1 OS=Homo sapiens GN=LRR1 PE=1 SV=2	9031.ENSGALP00000019946	peptidylprolyl isomerase (cyclophilin)-like 5	COG4886	KOG0619	_	_
ENSGALG00000012285	1.595492774	5.519945305	-1.78424904	1.60E-19	1.46E-18	down	yes	1.915519788	1.215801863	1.655156671	5.237207434	5.619668572	5.70295991	1	50999516	51007562	+	BAIAP2L2	protein_coding	GO:0007009|plasma membrane organization; GO:0008286|insulin receptor signaling pathway; GO:0030838|positive regulation of actin filament polymerization; GO:0051017|actin filament bundle assembly; GO:0051764|actin crosslink formation; GO:0061024|membrane organization; GO:2000251|positive regulation of actin cytoskeleton reorganization	GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0012506|vesicle membrane; GO:0015629|actin cytoskeleton; GO:0030659|cytoplasmic vesicle membrane; GO:0044291|cell-cell contact zone; GO:0071439|clathrin complex	GO:0005543|phospholipid binding; GO:0042802|identical protein binding	ko:K20127|BAIAP2L	--	1843	XP_416266.3	XP_416266.3 brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 [Gallus gallus]	sp|Q80Y61|BI2L2_MOUSE	sp|Q80Y61|BI2L2_MOUSE Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 OS=Mus musculus GN=Baiap2l2 PE=1 SV=1	9031.ENSGALP00000020051	BAI1-associated protein 2-like 2	_	_	NOG25242	PF08397.8|IMD|IRSp53/MIM homology domain|ENSGALT00000020078|m.1393:12-222;PF14604.3|SH3_9|Variant SH3 domain|ENSGALT00000020078|m.1393:330-381
ENSGALG00000012295	0.643266582	0.244381201	1.360679783	0.003675517	0.007046054	up	yes	0.378921136	0.941519093	0.609359517	0.38008133	0.141536262	0.211526011	5	57938576	57947538	-	CDKL1	protein_coding	GO:0006468|protein phosphorylation; GO:0007507|heart development	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0043231|intracellular membrane-bounded organelle; GO:0070062|extracellular exosome	GO:0004693|cyclin-dependent protein serine/threonine kinase activity; GO:0005524|ATP binding	ko:K08824|CDKL	--	2503	XP_421464.3	XP_421464.3 cyclin-dependent kinase-like 1 [Gallus gallus]	sp|Q8CEQ0|CDKL1_MOUSE	sp|Q8CEQ0|CDKL1_MOUSE Cyclin-dependent kinase-like 1 OS=Mus musculus GN=Cdkl1 PE=2 SV=1	9031.ENSGALP00000020061	cyclin-dependent kinase-like 1 (CDC2-related kinase)	COG0515	KOG0593	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000020088|m.4162:4-287;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000020088|m.4162:8-206
ENSGALG00000012304	9.399871903	24.60397879	-1.387230896	2.54E-67	1.52E-65	down	yes	10.09798545	9.28216876	8.819461499	24.9371242	25.60011519	23.274697	4	60786295	60843850	+	NFKB1	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006351|transcription, DNA-templated; GO:0006954|inflammatory response; GO:0007249|I-kappaB kinase/NF-kappaB signaling; GO:0034097|response to cytokine; GO:0038061|NIK/NF-kappaB signaling; GO:0045087|innate immune response; GO:0045944|positive regulation of transcription by RNA polymerase II"	GO:0005634|nucleus; GO:0005829|cytosol; GO:0033256|I-kappaB/NF-kappaB complex	"GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding; GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0003682|chromatin binding; GO:0051059|NF-kappaB binding"	ko:K02580|NFKB1	ko01523|Antifolate resistance; ko04010|MAPK signaling pathway; ko04014|Ras signaling pathway; ko04024|cAMP signaling pathway; ko04062|Chemokine signaling pathway; ko04064|NF-kappa B signaling pathway; ko04066|HIF-1 signaling pathway; ko04071|Sphingolipid signaling pathway; ko04151|PI3K-Akt signaling pathway; ko04210|Apoptosis; ko04211|Longevity regulating pathway; ko04380|Osteoclast differentiation; ko04620|Toll-like receptor signaling pathway; ko04621|NOD-like receptor signaling pathway; ko04622|RIG-I-like receptor signaling pathway; ko04623|Cytosolic DNA-sensing pathway; ko04624|Toll and Imd signaling pathway; ko04657|IL-17 signaling pathway; ko04658|Th1 and Th2 cell differentiation; ko04659|Th17 cell differentiation; ko04660|T cell receptor signaling pathway; ko04662|B cell receptor signaling pathway; ko04668|TNF signaling pathway; ko04722|Neurotrophin signaling pathway; ko04917|Prolactin signaling pathway; ko04920|Adipocytokine signaling pathway; ko04931|Insulin resistance; ko04932|Non-alcoholic fatty liver disease (NAFLD); ko04933|AGE-RAGE signaling pathway in diabetic complications; ko05030|Cocaine addiction; ko05120|Epithelial cell signaling in Helicobacter pylori infection; ko05131|Shigellosis; ko05132|Salmonella infection; ko05133|Pertussis; ko05134|Legionellosis; ko05140|Leishmaniasis; ko05142|Chagas disease (American trypanosomiasis); ko05145|Toxoplasmosis; ko05146|Amoebiasis; ko05152|Tuberculosis; ko05160|Hepatitis C; ko05161|Hepatitis B; ko05162|Measles; ko05164|Influenza A; ko05166|HTLV-I infection; ko05168|Herpes simplex infection; ko05169|Epstein-Barr virus infection; ko05200|Pathways in cancer; ko05202|Transcriptional misregulation in cancer; ko05203|Viral carcinogenesis; ko05206|MicroRNAs in cancer; ko05212|Pancreatic cancer; ko05215|Prostate cancer; ko05220|Chronic myeloid leukemia; ko05221|Acute myeloid leukemia; ko05222|Small cell lung cancer; ko05321|Inflammatory bowel disease (IBD); ko05418|Fluid shear stress and atherosclerosis	4013	XP_015140901.1	XP_015140901.1 nuclear factor NF-kappa-B p105 subunit isoform X1 [Gallus gallus]	sp|Q04861|NFKB1_CHICK	sp|Q04861|NFKB1_CHICK Nuclear factor NF-kappa-B p105 subunit OS=Gallus gallus GN=NFKB1 PE=2 SV=2	9031.ENSGALP00000020084	Nuclear factor NF-kappa-B p105 subunit [Contains Nuclear factor NF-kappa-B p50 subunit]; P10 [...] 	COG0666	KOG0504	NOG119056	PF00554.19|RHD_DNA_bind|Rel homology DNA-binding domain|ENSGALT00000037607|m.949:49-247;PF16179.2|RHD_dimer|Rel homology dimerisation domain|ENSGALT00000037607|m.949:256-357;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000037607|m.949:524-609;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000037607|m.949:584-678;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000037607|m.949:617-713;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000037607|m.949:654-746;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000037607|m.949:614-669;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000037607|m.949:650-703;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000037607|m.949:582-610;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000037607|m.949:612-638;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000037607|m.949:576-620;PF00531.19|Death|Death domain|ENSGALT00000037607|m.949:815-890
ENSGALG00000012322	0.715537562	1.785539965	-1.307295554	4.51E-06	1.33E-05	down	yes	0.745738545	0.495515885	0.905358254	1.604156285	1.861788986	1.890674625	13	18270817	18306102	+	KCTD16	protein_coding	GO:0008277|regulation of G protein-coupled receptor signaling pathway; GO:0051260|protein homooligomerization	GO:0030054|cell junction; GO:0042734|presynaptic membrane; GO:0043235|receptor complex; GO:0045211|postsynaptic membrane	--	--	--	2261	XP_425217.2	XP_425217.2 BTB/POZ domain-containing protein KCTD16 [Gallus gallus]	sp|Q68DU8|KCD16_HUMAN	sp|Q68DU8|KCD16_HUMAN BTB/POZ domain-containing protein KCTD16 OS=Homo sapiens GN=KCTD16 PE=1 SV=1	9031.ENSGALP00000020111	potassium channel tetramerisation domain containing 16	_	KOG2723	_	PF02214.19|BTB_2|BTB/POZ domain|ENSGALT00000020138|m.9125:27-118
ENSGALG00000012345	11.57686852	31.3329407	-1.43564983	1.59E-80	1.31E-78	down	yes	10.97087192	12.18536703	11.5743666	30.51413576	32.02938778	31.45529855	3	47909859	48062234	+	UST	protein_coding	GO:0030010|establishment of cell polarity; GO:0050770|regulation of axonogenesis	GO:0000139|Golgi membrane; GO:0016021|integral component of membrane	GO:0008146|sulfotransferase activity	ko:K03193|UST	ko00532|Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	3069	XP_025004672.1	XP_025004672.1 uronyl 2-sulfotransferase isoform X2 [Gallus gallus]	sp|Q8BUB6|UST_MOUSE	sp|Q8BUB6|UST_MOUSE Uronyl 2-sulfotransferase OS=Mus musculus GN=Ust PE=2 SV=3	_	_	_	_	_	PF03567.11|Sulfotransfer_2|Sulfotransferase family|ENSGALT00000020168|m.11925:107-359;PF06990.8|Gal-3-0_sulfotr|Galactose-3-O-sulfotransferase|ENSGALT00000020168|m.11925:93-315
ENSGALG00000012374	1.465816272	3.790475262	-1.364666716	2.34E-23	2.66E-22	down	yes	1.568568266	1.455197717	1.373682832	3.784920456	3.528050895	4.058454435	5	58189492	58216673	+	FRMD6	protein_coding	GO:0003383|apical constriction; GO:0031032|actomyosin structure organization; GO:0032970|regulation of actin filament-based process; GO:0034613|cellular protein localization	GO:0005737|cytoplasm; GO:0005856|cytoskeleton; GO:0005886|plasma membrane; GO:0043296|apical junction complex	GO:0005200|structural constituent of cytoskeleton	ko:K16822|FRMD6	ko04390|Hippo signaling pathway; ko04392|Hippo signaling pathway -multiple species	3784	XP_004936575.2	XP_004936575.2 FERM domain-containing protein 6 isoform X2 [Gallus gallus]	sp|Q96NE9|FRMD6_HUMAN	sp|Q96NE9|FRMD6_HUMAN FERM domain-containing protein 6 OS=Homo sapiens GN=FRMD6 PE=1 SV=1	9031.ENSGALP00000020178	FERM domain containing 6	_	KOG4371	_	PF09380.7|FERM_C|FERM C-terminal PH-like domain|ENSGALT00000020205|m.4192:237-321;PF00373.15|FERM_M|FERM central domain|ENSGALT00000020205|m.4192:115-226;PF09379.7|FERM_N|FERM N-terminal domain|ENSGALT00000020205|m.4192:20-81
ENSGALG00000012392	0.118115444	0.592337388	-2.233127407	0.00027373	0.000628441	down	yes	0.228099953	0.104526927	0.021719453	0.707844918	0.496169837	0.572997408	3	48530510	48546549	+	IYD	protein_coding	GO:0006570|tyrosine metabolic process; GO:0006590|thyroid hormone generation; GO:0042403|thyroid hormone metabolic process; GO:0055114|oxidation-reduction process	GO:0005654|nucleoplasm; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0030659|cytoplasmic vesicle membrane	GO:0004447|iodide peroxidase activity; GO:0010181|FMN binding; GO:0016491|oxidoreductase activity	"ko:K17231|IYD,DEHAL1"	ko04918|Thyroid hormone synthesis	1848	XP_419670.2	XP_419670.2 iodotyrosine deiodinase 1 [Gallus gallus]	sp|Q6PHW0|IYD1_HUMAN	sp|Q6PHW0|IYD1_HUMAN Iodotyrosine deiodinase 1 OS=Homo sapiens GN=IYD PE=1 SV=2	9031.ENSGALP00000020208	iodotyrosine deiodinase	COG0778	KOG3936	_	PF00881.21|Nitroreductase|Nitroreductase family|ENSGALT00000020235|m.11941:90-259
ENSGALG00000012395	4.347804734	10.65456738	-1.291151984	7.55E-45	2.31E-43	down	yes	4.47141683	4.48797073	4.08402664	10.36092508	11.19432735	10.40844972	3	48624389	48741485	+	PLEKHG1	protein_coding	GO:0035023|regulation of Rho protein signal transduction	GO:0005634|nucleus; GO:0005654|nucleoplasm	GO:0005089|Rho guanyl-nucleotide exchange factor activity	--	--	4855	XP_004935669.1	XP_004935669.1 pleckstrin homology domain-containing family G member 1 isoform X1 [Gallus gallus]	sp|Q9ULL1|PKHG1_HUMAN	sp|Q9ULL1|PKHG1_HUMAN Pleckstrin homology domain-containing family G member 1 OS=Homo sapiens GN=PLEKHG1 PE=1 SV=2	9031.ENSGALP00000036794	"pleckstrin homology domain containing, family G (with RhoGef domain) member 1"	COG5422	KOG3518	_	PF00621.17|RhoGEF|RhoGEF domain|ENSGALT00000037587|m.11942:176-350
ENSGALG00000012418	1.188156498	4.326034048	-1.855559726	4.13E-07	1.38E-06	down	yes	0.666515617	1.439413678	1.458540199	4.726997479	4.855115429	3.395989236	7	32639735	32697227	+	KYNU	protein_coding	GO:0006569|tryptophan catabolic process; GO:0009435|NAD biosynthetic process; GO:0019441|tryptophan catabolic process to kynurenine; GO:0019442|tryptophan catabolic process to acetyl-CoA; GO:0019805|quinolinate biosynthetic process; GO:0034341|response to interferon-gamma; GO:0034516|response to vitamin B6; GO:0043420|anthranilate metabolic process; GO:0097053|L-kynurenine catabolic process	GO:0005739|mitochondrion; GO:0005829|cytosol	GO:0030170|pyridoxal phosphate binding; GO:0030429|kynureninase activity; GO:0042803|protein homodimerization activity	"ko:K01556|KYNU,kynU"	ko00380|Tryptophan metabolism; ko01100|Metabolic pathways	4042	XP_004943069.1	XP_004943069.1 kynureninase isoform X2 [Gallus gallus]	sp|Q16719|KYNU_HUMAN	sp|Q16719|KYNU_HUMAN Kynureninase OS=Homo sapiens GN=KYNU PE=1 SV=1	9031.ENSGALP00000020272	kynureninase (L-kynurenine hydrolase)	COG3844	KOG3846	_	PF00266.16|Aminotran_5|Aminotransferase class-V|ENSGALT00000057444|m.6716:70-374
ENSGALG00000012420	3.939022703	1.209201541	1.69555903	0.000106237	0.000259692	up	yes	4.713579856	3.641143747	3.462344506	2.184594859	0.565918951	0.877090814	1	51166508	51169768	-	CG-1B	protein_coding	--	--	GO:0030246|carbohydrate binding	--	--	626	NP_990826.1	NP_990826.1 beta-galactoside-binding lectin [Gallus gallus]	sp|P07583|LEG4_CHICK	sp|P07583|LEG4_CHICK Beta-galactoside-binding lectin OS=Gallus gallus PE=1 SV=2	9031.ENSGALP00000020275	Beta-galactoside-binding lectin (14 kDa lectin)(C-14); This protein binds beta-galactoside.  [...] 	_	KOG3587	_	PF00337.19|Gal-bind_lectin|Galactoside-binding lectin|ENSGALT00000020302|m.1429:61-185
ENSGALG00000012421	0.362108203	1.943372998	-2.392173361	2.01E-18	1.72E-17	down	yes	0.231973348	0.425207651	0.429143609	1.969500577	2.097019688	1.76359873	7	32698930	33027332	+	ARHGAP15	protein_coding	GO:0007165|signal transduction; GO:0008360|regulation of cell shape	GO:0005737|cytoplasm; GO:0016020|membrane	GO:0005096|GTPase activator activity	ko:K20637|ARHGAP15	--	2939	NP_001008476.1	NP_001008476.1 rho GTPase-activating protein 15 [Gallus gallus]	sp|Q5ZMM3|RHG15_CHICK	sp|Q5ZMM3|RHG15_CHICK Rho GTPase-activating protein 15 OS=Gallus gallus GN=ARHGAP15 PE=2 SV=1	9031.ENSGALP00000037032	Rho GTPase-activating protein 15 (Rho-type GTPase-activating protein 15)(ArhGAP15); GTPase a [...] 	_	KOG1450;KOG4269	_	PF00620.24|RhoGAP|RhoGAP domain|ENSGALT00000075184|m.6718:295-444;PF00169.26|PH|PH domain|ENSGALT00000075184|m.6718:81-189
ENSGALG00000012446	0.563361598	0.134127683	1.992097813	7.58E-05	0.000189133	up	yes	0.521049089	0.557132398	0.611903306	0.228656949	0.068691003	0.105035097	1	51333318	51335744	+	ELFN2	protein_coding	GO:0010923|negative regulation of phosphatase activity	GO:0005615|extracellular space; GO:0016021|integral component of membrane	GO:0004864|protein phosphatase inhibitor activity; GO:0019902|phosphatase binding	ko:K17568|ELFN2	--	2427	XP_004937804.1	XP_004937804.1 protein phosphatase 1 regulatory subunit 29 [Gallus gallus]	sp|Q5R3F8|PPR29_HUMAN	sp|Q5R3F8|PPR29_HUMAN Protein phosphatase 1 regulatory subunit 29 OS=Homo sapiens GN=ELFN2 PE=1 SV=1	9031.ENSGALP00000020319	extracellular leucine-rich repeat and fibronectin type III containing 2	_	KOG4237	_	PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000020346|m.1450:87-146;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000020346|m.1450:139-193;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000020346|m.1450:87-184
ENSGALG00000012453	21.89799407	45.51485549	-1.055197043	2.30E-49	8.12E-48	down	yes	22.74368716	21.83494584	21.11534921	45.4986152	47.75083964	43.29511162	7	34721338	34761957	+	EPC2	protein_coding	"GO:0006281|DNA repair; GO:0006351|transcription, DNA-templated; GO:0006357|regulation of transcription by RNA polymerase II; GO:0016573|histone acetylation"	GO:0032777|Piccolo NuA4 histone acetyltransferase complex	--	ko:K11322|EPC	--	2838	XP_422154.3	XP_422154.3 enhancer of polycomb homolog 2 [Gallus gallus]	sp|Q52LR7|EPC2_HUMAN	sp|Q52LR7|EPC2_HUMAN Enhancer of polycomb homolog 2 OS=Homo sapiens GN=EPC2 PE=1 SV=2	9031.ENSGALP00000020328	enhancer of polycomb homolog 2 (Drosophila)	_	KOG2261	_	PF06752.9|E_Pc_C|Enhancer of Polycomb C-terminus|ENSGALT00000020355|m.6733:578-807;PF10513.6|EPL1|Enhancer of polycomb-like|ENSGALT00000020355|m.6733:7-148
ENSGALG00000012454	1.786895217	13.69986025	-2.931635677	3.04E-110	4.90E-108	down	yes	1.690020677	1.610862017	2.059802956	14.51510926	12.68468975	13.89978173	1	51385635	51405059	-	CYTH4	protein_coding	GO:0032012|regulation of ARF protein signal transduction	GO:0000139|Golgi membrane; GO:0005829|cytosol; GO:0005886|plasma membrane	GO:0005086|ARF guanyl-nucleotide exchange factor activity; GO:0008289|lipid binding	ko:K18441|CYTH	ko04072|Phospholipase D signaling pathway; ko04144|Endocytosis	2595	XP_015718032.1	XP_015718032.1 PREDICTED: cytohesin-4 isoform X1 [Coturnix japonica]	sp|Q9UIA0|CYH4_HUMAN	sp|Q9UIA0|CYH4_HUMAN Cytohesin-4 OS=Homo sapiens GN=CYTH4 PE=1 SV=1	9031.ENSGALP00000020330	"pleckstrin homology, Sec7 and coiled-coil domains 4 "	COG5307	KOG0930	_	PF01369.17|Sec7|Sec7 domain|ENSGALT00000020357|m.1454:74-255;PF00169.26|PH|PH domain|ENSGALT00000020357|m.1454:273-386
ENSGALG00000012472	1.255818104	3.226642516	-1.354427923	3.79E-13	2.19E-12	down	yes	1.382754731	1.133111907	1.251587674	2.759699174	3.699444756	3.220783617	1	51457537	51470895	+	IL2RB	protein_coding	--	GO:0016021|integral component of membrane	GO:0004896|cytokine receptor activity	"ko:K05069|IL2RB,CD122"	ko04060|Cytokine-cytokine receptor interaction; ko04144|Endocytosis; ko04151|PI3K-Akt signaling pathway; ko04630|Jak-STAT signaling pathway; ko04658|Th1 and Th2 cell differentiation; ko04659|Th17 cell differentiation; ko05162|Measles; ko05166|HTLV-I infection; ko05202|Transcriptional misregulation in cancer	3239	NP_001305918.1	NP_001305918.1 interleukin-2 receptor subunit beta precursor [Gallus gallus]	sp|Q38J84|IL2RB_PANTR	sp|Q38J84|IL2RB_PANTR Interleukin-2 receptor subunit beta OS=Pan troglodytes GN=IL2RB PE=2 SV=1	_	_	_	_	_	_
ENSGALG00000012537	0.86341147	2.193126989	-1.334819272	0.000124306	0.000300517	down	yes	0.414346703	0.860764861	1.315122846	1.935209042	2.266904393	2.377267532	7	35735910	35765494	+	KCNJ3	protein_coding	GO:1990573|potassium ion import across plasma membrane	GO:0005887|integral component of plasma membrane	GO:0005242|inward rectifier potassium channel activity; GO:0015467|G-protein activated inward rectifier potassium channel activity	ko:K04997|KCNJ3	ko04713|Circadian entrainment; ko04723|Retrograde endocannabinoid signaling; ko04724|Glutamatergic synapse; ko04725|Cholinergic synapse; ko04726|Serotonergic synapse; ko04728|Dopaminergic synapse; ko04915|Estrogen signaling pathway; ko04921|Oxytocin signaling pathway; ko05032|Morphine addiction	1526	XP_015724701.1	XP_015724701.1 PREDICTED: G protein-activated inward rectifier potassium channel 1 [Coturnix japonica]	sp|Q90854|KCNJ3_CHICK	sp|Q90854|KCNJ3_CHICK G protein-activated inward rectifier potassium channel 1 OS=Gallus gallus GN=KCNJ3 PE=2 SV=1	9031.ENSGALP00000020449	"G protein-activated inward rectifier potassium channel 1 (GIRK1)(Potassium channel, inwardly [...] "	_	KOG3827	_	PF01007.17|IRK|Inward rectifier potassium channel|ENSGALT00000020476|m.6784:52-369
ENSGALG00000012538	3.850713236	18.74653244	-2.280453834	1.20E-68	7.53E-67	down	yes	4.300588048	2.892600273	4.358951388	19.53222253	19.86921734	16.83815744	7	36032926	36038300	-	NR4A2	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0001666|response to hypoxia; GO:0001764|neuron migration; GO:0001975|response to amphetamine; GO:0006351|transcription, DNA-templated; GO:0008344|adult locomotory behavior; GO:0009791|post-embryonic development; GO:0021952|central nervous system projection neuron axonogenesis; GO:0021986|habenula development; GO:0031668|cellular response to extracellular stimulus; GO:0034599|cellular response to oxidative stress; GO:0042053|regulation of dopamine metabolic process; GO:0042416|dopamine biosynthetic process; GO:0042551|neuron maturation; GO:0043085|positive regulation of catalytic activity; GO:0043524|negative regulation of neuron apoptotic process; GO:0043576|regulation of respiratory gaseous exchange; GO:0045444|fat cell differentiation; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0051866|general adaptation syndrome; GO:0071376|cellular response to corticotropin-releasing hormone stimulus; GO:0071542|dopaminergic neuron differentiation; GO:2001234|negative regulation of apoptotic signaling pathway"	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0016607|nuclear speck	"GO:0000979|RNA polymerase II core promoter sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003707|steroid hormone receptor activity; GO:0004879|nuclear receptor activity; GO:0008270|zinc ion binding; GO:0035259|glucocorticoid receptor binding; GO:0046982|protein heterodimerization activity"	"ko:K08558|NR4A2,NURR1"	ko04925|Aldosterone synthesis and secretion	2849	XP_015145687.1	XP_015145687.1 nuclear receptor subfamily 4 group A member 2 isoform X1 [Gallus gallus]	sp|Q08E53|NR4A2_BOVIN	sp|Q08E53|NR4A2_BOVIN Nuclear receptor subfamily 4 group A member 2 OS=Bos taurus GN=NR4A2 PE=2 SV=1	9031.ENSGALP00000020451	"nuclear receptor subfamily 4, group A, member 2"	_	KOG4217	_	"PF00104.27|Hormone_recep|Ligand-binding domain of nuclear hormone receptor|ENSGALT00000073703|m.6785:399-578;PF00105.15|zf-C4|Zinc finger, C4 type (two domains)|ENSGALT00000073703|m.6785:262-330"
ENSGALG00000012550	5.668153519	12.01029735	-1.081978824	2.36E-15	1.62E-14	down	yes	6.255227058	5.395691661	5.353541837	11.41844805	11.91847071	12.6939733	1	52103308	52109433	-	HMOX1	protein_coding	GO:0006788|heme oxidation; GO:0006979|response to oxidative stress; GO:0042167|heme catabolic process; GO:0055072|iron ion homeostasis	GO:0005783|endoplasmic reticulum; GO:0016020|membrane	GO:0004392|heme oxygenase (decyclizing) activity; GO:0020037|heme binding; GO:0046872|metal ion binding	ko:K00510|HMOX1	ko00860|Porphyrin and chlorophyll metabolism; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko04066|HIF-1 signaling pathway; ko04216|Ferroptosis; ko04978|Mineral absorption; ko05206|MicroRNAs in cancer; ko05418|Fluid shear stress and atherosclerosis	1432	NP_990675.1	NP_990675.1 heme oxygenase 1 [Gallus gallus]	sp|P14791|HMOX1_CHICK	sp|P14791|HMOX1_CHICK Heme oxygenase 1 OS=Gallus gallus GN=HMOX1 PE=1 SV=2	9031.ENSGALP00000036970	Heme oxygenase 1 (HO-1)(EC 1.14.99.3); Heme oxygenase cleaves the heme ring at the alpha met [...] 	COG5398	KOG4480	_	PF01126.17|Heme_oxygenase|Heme oxygenase|ENSGALT00000037765|m.1498:44-247
ENSGALG00000012555	0.244682361	0.92195544	-1.871561934	9.44E-05	0.000232672	down	yes	0.114670488	0.35732513	0.262051464	1.110677227	0.929711055	0.725478038	7	36314871	36353560	-	CCDC148	protein_coding	--	--	--	--	--	1838	XP_015145672.1	XP_015145672.1 coiled-coil domain-containing protein 148 isoform X1 [Gallus gallus]	sp|Q8HZY8|CC148_MACFA	sp|Q8HZY8|CC148_MACFA Coiled-coil domain-containing protein 148 OS=Macaca fascicularis GN=CCDC148 PE=2 SV=1	9031.ENSGALP00000020475	coiled-coil domain containing 148	_	_	NOG79436	_
ENSGALG00000012576	5.958364479	14.23665851	-1.255216035	1.77E-29	2.68E-28	down	yes	6.666848098	5.832055277	5.376190064	13.69735506	14.51101942	14.50160106	Z	39728943	39767984	-	RASEF	protein_coding	GO:0051260|protein homooligomerization	GO:0005829|cytosol; GO:0048471|perinuclear region of cytoplasm	GO:0003924|GTPase activity; GO:0005509|calcium ion binding; GO:0005525|GTP binding; GO:0019003|GDP binding; GO:0042802|identical protein binding	"ko:K17199|RASEF,RAB45"	--	2270	XP_003643075.3	XP_003643075.3 ras and EF-hand domain-containing protein isoform X1 [Gallus gallus]	sp|Q8IZ41|RASEF_HUMAN	sp|Q8IZ41|RASEF_HUMAN Ras and EF-hand domain-containing protein OS=Homo sapiens GN=RASEF PE=1 SV=1	59729.ENSTGUP00000003320	RAS and EF-hand domain-containing protein (Ras-related protein Rab-45) [Taeniopygia guttata]	COG1100	KOG0078	_	"PF00071.19|Ras|Ras family|ENSGALT00000020539|m.11312:557-723;PF08477.10|Roc|Ras of Complex, Roc, domain of DAPkinase|ENSGALT00000020539|m.11312:557-671;PF00025.18|Arf|ADP-ribosylation factor family|ENSGALT00000020539|m.11312:548-720;PF13499.3|EF-hand_7|EF-hand domain pair|ENSGALT00000020539|m.11312:45-105;PF13202.3|EF-hand_5|EF hand|ENSGALT00000020539|m.11312:47-70;PF13202.3|EF-hand_5|EF hand|ENSGALT00000020539|m.11312:83-103;PF01926.20|MMR_HSR1|50S ribosome-binding GTPase|ENSGALT00000020539|m.11312:557-669;PF13833.3|EF-hand_8|EF-hand domain pair|ENSGALT00000020539|m.11312:59-103"
ENSGALG00000012577	1.620354558	5.544797609	-1.768548602	3.57E-26	4.73E-25	down	yes	2.095931009	1.344646131	1.420486535	5.01433282	6.12557146	5.494488547	Z	39821677	39963817	-	FRMD3	protein_coding	GO:0031032|actomyosin structure organization	GO:0005856|cytoskeleton; GO:0016021|integral component of membrane	GO:0005200|structural constituent of cytoskeleton; GO:0008092|cytoskeletal protein binding	--	--	3379	XP_003643086.1	XP_003643086.1 FERM domain-containing protein 3 isoform X1 [Gallus gallus]	sp|A2A2Y4|FRMD3_HUMAN	sp|A2A2Y4|FRMD3_HUMAN FERM domain-containing protein 3 OS=Homo sapiens GN=FRMD3 PE=2 SV=1	59729.ENSTGUP00000003307	FERM domain-containing protein 3 (Band 4.1-like protein 4O)(Ovary type protein 4.1)(4.1O) [T [...] 	_	KOG3530	_	PF09380.7|FERM_C|FERM C-terminal PH-like domain|ENSGALT00000058547|m.11315:222-308;PF09379.7|FERM_N|FERM N-terminal domain|ENSGALT00000058547|m.11315:29-91;PF00373.15|FERM_M|FERM central domain|ENSGALT00000058547|m.11315:110-217;PF08736.8|FA|FERM adjacent (FA)|ENSGALT00000058547|m.11315:316-358
ENSGALG00000012583	4.572885633	1.685476868	1.434565182	1.39E-22	1.52E-21	up	yes	4.323948435	4.949946298	4.444762167	1.632491635	1.557531307	1.866407663	Z	39979314	39991612	+	IDNK	protein_coding	GO:0046177|D-gluconate catabolic process	--	GO:0005524|ATP binding; GO:0046316|gluconokinase activity	"ko:K00851|E2.7.1.12,gntK,idnK"	ko00030|Pentose phosphate pathway; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko01120|Microbial metabolism in diverse environments; ko01130|Biosynthesis of antibiotics; ko01200|Carbon metabolism	2372	XP_425027.2	XP_425027.2 probable gluconokinase isoform X3 [Gallus gallus]	sp|Q32PY9|GNTK_RAT	sp|Q32PY9|GNTK_RAT Probable gluconokinase OS=Rattus norvegicus GN=Idnk PE=2 SV=1	9031.ENSGALP00000020517	chromosome 9 open reading frame 103	COG3265	KOG3354	_	PF01202.19|SKI|Shikimate kinase|ENSGALT00000098396|m.11318:30-155;PF13671.3|AAA_33|AAA domain|ENSGALT00000098396|m.11318:23-171;PF13238.3|AAA_18|AAA domain|ENSGALT00000098396|m.11318:24-154
ENSGALG00000012586	4.237914023	12.93431181	-1.607491795	3.42E-35	6.89E-34	down	yes	4.586581849	4.383761841	3.743398377	13.41164402	13.44286051	11.94843092	Z	40025493	40048181	-	GKAP1	protein_coding	GO:0007165|signal transduction	GO:0005794|Golgi apparatus	GO:0042802|identical protein binding	--	--	1669	XP_015135856.1	XP_015135856.1 G kinase-anchoring protein 1 isoform X3 [Gallus gallus]	sp|Q5VSY0|GKAP1_HUMAN	sp|Q5VSY0|GKAP1_HUMAN G kinase-anchoring protein 1 OS=Homo sapiens GN=GKAP1 PE=1 SV=2	9031.ENSGALP00000020523	G kinase anchoring protein 1	_	_	NOG39546	_
ENSGALG00000012588	1.510867802	3.074500093	-1.020141934	3.22E-10	1.46E-09	down	yes	1.735040533	1.335288776	1.462274098	2.675329788	3.328810621	3.219359871	Z	40053080	40077364	-	KIF27	protein_coding	GO:0003351|epithelial cilium movement involved in extracellular fluid movement; GO:0007018|microtubule-based movement; GO:0021591|ventricular system development; GO:0060271|cilium assembly	GO:0005737|cytoplasm; GO:0005871|kinesin complex; GO:0005874|microtubule; GO:0005929|cilium; GO:0070062|extracellular exosome	"GO:0005524|ATP binding; GO:0008017|microtubule binding; GO:0008574|ATP-dependent microtubule motor activity, plus-end-directed"	ko:K10395|KIF4_21_27	--	4282	XP_004949261.1	XP_004949261.1 kinesin-like protein KIF27 isoform X1 [Gallus gallus]	sp|Q7M6Z5|KIF27_RAT	sp|Q7M6Z5|KIF27_RAT Kinesin-like protein KIF27 OS=Rattus norvegicus GN=Kif27 PE=1 SV=1	9031.ENSGALP00000020526	"PREDICTED: Gallus gallus hypothetical LOC427456 (LOC427456), mRNA"	COG5059	KOG0244	_	PF00225.20|Kinesin|Kinesin motor domain|ENSGALT00000102472|m.11330:15-350;PF16796.2|Microtub_bd|Microtubule binding|ENSGALT00000102472|m.11330:11-151
ENSGALG00000012606	4.224826708	1.934753873	1.122715354	1.48E-13	8.83E-13	up	yes	3.827108936	4.747718781	4.099652406	1.97296852	1.783894667	2.047398433	Z	40832093	40839365	-	ISCA1	protein_coding	GO:0016226|iron-sulfur cluster assembly; GO:0097428|protein maturation by iron-sulfur cluster transfer	GO:0005759|mitochondrial matrix	"GO:0005198|structural molecule activity; GO:0008198|ferrous iron binding; GO:0051537|2 iron, 2 sulfur cluster binding"	"ko:K13628|iscA,ISCA1"	--	3084	NP_001258865.1	"NP_001258865.1 iron-sulfur cluster assembly 1 homolog, mitochondrial [Gallus gallus]"	sp|Q5ZJ74|ISCA1_CHICK	"sp|Q5ZJ74|ISCA1_CHICK Iron-sulfur cluster assembly 1 homolog, mitochondrial OS=Gallus gallus GN=ISCA1 PE=2 SV=1"	9031.ENSGALP00000020553	"Iron-sulfur cluster assembly 1 homolog, mitochondrial Precursor (HESB-like domain-containing [...] "	COG0316	KOG1120	_	PF01521.17|Fe-S_biosyn|Iron-sulphur cluster biosynthesis|ENSGALT00000020582|m.11356:171-271
ENSGALG00000012704	22.79037458	45.69910353	-1.003423998	5.78E-40	1.44E-38	down	yes	22.21798014	21.99182715	24.16131646	44.07730492	49.26095344	43.75905224	2	61479711	61493929	+	MYLIP	protein_coding	GO:0000209|protein polyubiquitination; GO:0006511|ubiquitin-dependent protein catabolic process; GO:0006928|movement of cell or subcellular component; GO:0007399|nervous system development; GO:0010989|negative regulation of low-density lipoprotein particle clearance; GO:0016567|protein ubiquitination; GO:0031648|protein destabilization; GO:0032802|low-density lipoprotein particle receptor catabolic process; GO:0032803|regulation of low-density lipoprotein particle receptor catabolic process; GO:0042632|cholesterol homeostasis; GO:0045732|positive regulation of protein catabolic process	GO:0005622|intracellular; GO:0005829|cytosol; GO:0005886|plasma membrane	GO:0004842|ubiquitin-protein transferase activity; GO:0008092|cytoskeletal protein binding; GO:0046872|metal ion binding; GO:0061630|ubiquitin protein ligase activity	"ko:K10637|MYLIP,MIR"	--	2751	NP_001012579.1	NP_001012579.1 E3 ubiquitin-protein ligase MYLIP [Gallus gallus]	sp|Q8WY64|MYLIP_HUMAN	sp|Q8WY64|MYLIP_HUMAN E3 ubiquitin-protein ligase MYLIP OS=Homo sapiens GN=MYLIP PE=1 SV=2	28377.ENSACAP00000003730	myosin regulatory light chain interacting protein	_	KOG0792	_	"PF09379.7|FERM_N|FERM N-terminal domain|ENSGALT00000020742|m.889:5-67;PF00373.15|FERM_M|FERM central domain|ENSGALT00000020742|m.889:86-190;PF13920.3|zf-C3HC4_3|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000020742|m.889:385-427;PF09380.7|FERM_C|FERM C-terminal PH-like domain|ENSGALT00000020742|m.889:194-278"
ENSGALG00000012732	0.33835024	0.154993932	1.078125589	0.018757002	0.031334281	up	yes	0.321198105	0.460300789	0.233551825	0.197702321	0.109710039	0.157569436	2	62237702	62532964	-	PHACTR1	protein_coding	GO:0031032|actomyosin structure organization; GO:0031532|actin cytoskeleton reorganization; GO:0043149|stress fiber assembly	GO:0005634|nucleus; GO:0005829|cytosol; GO:0030054|cell junction; GO:0045202|synapse	GO:0003779|actin binding; GO:0004864|protein phosphatase inhibitor activity; GO:0008157|protein phosphatase 1 binding	--	--	2376	XP_015131307.1	XP_015131307.1 phosphatase and actin regulator 1 isoform X1 [Gallus gallus]	sp|Q801X6|PHAR1_CHICK	sp|Q801X6|PHAR1_CHICK Phosphatase and actin regulator 1 OS=Gallus gallus GN=PHACTR1 PE=2 SV=1	9031.ENSGALP00000020751	Phosphatase and actin regulator 1 	_	KOG4339	_	PF02755.12|RPEL|RPEL repeat|ENSGALT00000020780|m.918:344-365;PF02755.12|RPEL|RPEL repeat|ENSGALT00000020780|m.918:382-404;PF02755.12|RPEL|RPEL repeat|ENSGALT00000020780|m.918:421-440
ENSGALG00000012735	3.686093194	25.07476226	-2.762738226	2.25E-42	6.31E-41	down	yes	3.152458322	4.886928666	3.018892595	27.84916005	24.04515364	23.32997308	2	62675250	62679088	-	EDN1	protein_coding	GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0001501|skeletal system development; GO:0001516|prostaglandin biosynthetic process; GO:0001569|branching involved in blood vessel morphogenesis; GO:0001666|response to hypoxia; GO:0001701|in utero embryonic development; GO:0001821|histamine secretion; GO:0003100|regulation of systemic arterial blood pressure by endothelin; GO:0006885|regulation of pH; GO:0007166|cell surface receptor signaling pathway; GO:0007186|G protein-coupled receptor signaling pathway; GO:0007204|positive regulation of cytosolic calcium ion concentration; GO:0007205|protein kinase C-activating G protein-coupled receptor signaling pathway; GO:0007267|cell-cell signaling; GO:0007507|heart development; GO:0007585|respiratory gaseous exchange by respiratory system; GO:0007589|body fluid secretion; GO:0008217|regulation of blood pressure; GO:0008284|positive regulation of cell population proliferation; GO:0009953|dorsal/ventral pattern formation; GO:0010193|response to ozone; GO:0010259|multicellular organism aging; GO:0010460|positive regulation of heart rate; GO:0010613|positive regulation of cardiac muscle hypertrophy; GO:0010870|positive regulation of receptor biosynthetic process; GO:0014032|neural crest cell development; GO:0014065|phosphatidylinositol 3-kinase signaling; GO:0014823|response to activity; GO:0014824|artery smooth muscle contraction; GO:0014826|vein smooth muscle contraction; GO:0016049|cell growth; GO:0019229|regulation of vasoconstriction; GO:0019233|sensory perception of pain; GO:0019722|calcium-mediated signaling; GO:0030072|peptide hormone secretion; GO:0030185|nitric oxide transport; GO:0030335|positive regulation of cell migration; GO:0031583|phospholipase D-activating G protein-coupled receptor signaling pathway; GO:0032269|negative regulation of cellular protein metabolic process; GO:0032308|positive regulation of prostaglandin secretion; GO:0032496|response to lipopolysaccharide; GO:0033574|response to testosterone; GO:0034392|negative regulation of smooth muscle cell apoptotic process; GO:0034696|response to prostaglandin F; GO:0035094|response to nicotine; GO:0035690|cellular response to drug; GO:0035810|positive regulation of urine volume; GO:0035815|positive regulation of renal sodium excretion; GO:0035994|response to muscle stretch; GO:0042045|epithelial fluid transport; GO:0042310|vasoconstriction; GO:0042313|protein kinase C deactivation; GO:0042474|middle ear morphogenesis; GO:0042482|positive regulation of odontogenesis; GO:0042554|superoxide anion generation; GO:0043179|rhythmic excitation; GO:0043200|response to amino acid; GO:0043406|positive regulation of MAP kinase activity; GO:0043507|positive regulation of JUN kinase activity; GO:0044321|response to leptin; GO:0045793|positive regulation of cell size; GO:0045840|positive regulation of mitotic nuclear division; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0045987|positive regulation of smooth muscle contraction; GO:0046887|positive regulation of hormone secretion; GO:0046888|negative regulation of hormone secretion; GO:0048016|inositol phosphate-mediated signaling; GO:0048514|blood vessel morphogenesis; GO:0048661|positive regulation of smooth muscle cell proliferation; GO:0051091|positive regulation of DNA-binding transcription factor activity; GO:0051216|cartilage development; GO:0051482|positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway; GO:0051771|negative regulation of nitric-oxide synthase biosynthetic process; GO:0051899|membrane depolarization; GO:0051930|regulation of sensory perception of pain; GO:0060137|maternal process involved in parturition; GO:0060298|positive regulation of sarcomere organization; GO:0060585|positive regulation of prostaglandin-endoperoxide synthase activity; GO:0061051|positive regulation of cell growth involved in cardiac muscle cell development; GO:0071277|cellular response to calcium ion; GO:0071346|cellular response to interferon-gamma; GO:0071347|cellular response to interleukin-1; GO:0071356|cellular response to tumor necrosis factor; GO:0071375|cellular response to peptide hormone stimulus; GO:0071385|cellular response to glucocorticoid stimulus; GO:0071389|cellular response to mineralocorticoid stimulus; GO:0071398|cellular response to fatty acid; GO:0071456|cellular response to hypoxia; GO:0071548|response to dexamethasone; GO:0071560|cellular response to transforming growth factor beta stimulus; GO:0090023|positive regulation of neutrophil chemotaxis; GO:1902074|response to salt; GO:1904659|glucose transmembrane transport	GO:0005615|extracellular space; GO:0005737|cytoplasm; GO:0033093|Weibel-Palade body; GO:0045178|basal part of cell; GO:0048237|rough endoplasmic reticulum lumen	GO:0005102|signaling receptor binding; GO:0005125|cytokine activity; GO:0005179|hormone activity; GO:0031707|endothelin A receptor binding; GO:0031708|endothelin B receptor binding	ko:K16366|EDN1	ko04066|HIF-1 signaling pathway; ko04668|TNF signaling pathway; ko04916|Melanogenesis; ko04933|AGE-RAGE signaling pathway in diabetic complications; ko05418|Fluid shear stress and atherosclerosis	585	XP_418943.2	XP_418943.2 endothelin-1 [Gallus gallus]	sp|P22387|EDN1_MOUSE	sp|P22387|EDN1_MOUSE Endothelin-1 OS=Mus musculus GN=Edn1 PE=1 SV=3	9031.ENSGALP00000020756	endothelin 1	_	_	NOG46593	PF00322.14|Endothelin|Endothelin family|ENSGALT00000020785|m.922:31-59
ENSGALG00000012747	14.97302644	65.66884489	-2.132099689	7.32E-133	2.27E-130	down	yes	14.04900177	15.37584408	15.49423346	67.2036988	72.84706719	56.95576867	2	63027555	63115283	+	NEDD9	protein_coding	GO:0007010|cytoskeleton organization; GO:0007049|cell cycle; GO:0007155|cell adhesion; GO:0007165|signal transduction; GO:0007229|integrin-mediated signaling pathway; GO:0040008|regulation of growth; GO:0051017|actin filament bundle assembly; GO:0051301|cell division	GO:0000922|spindle pole; GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005794|Golgi apparatus; GO:0005819|spindle; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0005925|focal adhesion; GO:0005938|cell cortex; GO:0030027|lamellipodium	--	"ko:K16832|NEDD9,HEF1,CASL"	--	3293	XP_418946.4	XP_418946.4 enhancer of filamentation 1 isoform X1 [Gallus gallus]	sp|Q14511|CASL_HUMAN	sp|Q14511|CASL_HUMAN Enhancer of filamentation 1 OS=Homo sapiens GN=NEDD9 PE=1 SV=1	9031.ENSGALP00000020772	Enhancer of filamentation 1 homolog Fragment 	_	_	NOG82196	PF12026.5|DUF3513|Domain of unknown function (DUF3513)|ENSGALT00000102872|m.928:612-820;PF08824.7|Serine_rich|Serine rich protein interaction domain|ENSGALT00000102872|m.928:400-555;PF14604.3|SH3_9|Variant SH3 domain|ENSGALT00000102872|m.928:10-60;PF00018.25|SH3_1|SH3 domain|ENSGALT00000102872|m.928:9-56;PF07653.14|SH3_2|Variant SH3 domain|ENSGALT00000102872|m.928:8-61
ENSGALG00000012770	0.123585291	0.980440072	-2.890308527	1.42E-07	4.99E-07	down	yes	0.115360896	0.211456772	0.043938204	1.160757183	1.072183096	0.708379937	2	63228311	63243379	+	ENSGALG00000012770	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated; GO:0006468|protein phosphorylation; GO:0007275|multicellular organism development; GO:0007283|spermatogenesis; GO:0010468|regulation of gene expression; GO:0030154|cell differentiation; GO:0035556|intracellular signal transduction; GO:0042073|intraciliary transport; GO:0045494|photoreceptor cell maintenance; GO:0046777|protein autophosphorylation; GO:0060271|cilium assembly"	GO:0001750|photoreceptor outer segment; GO:0001917|photoreceptor inner segment; GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005813|centrosome; GO:0005929|cilium; GO:0030496|midbody; GO:0072686|mitotic spindle	GO:0003713|transcription coactivator activity; GO:0004672|protein kinase activity; GO:0004674|protein serine/threonine kinase activity; GO:0005524|ATP binding; GO:0046872|metal ion binding	ko:K08829|MAK	--	1827	XP_015131470.1	XP_015131470.1 serine/threonine-protein kinase MAK isoform X2 [Gallus gallus]	sp|P20794|MAK_HUMAN	sp|P20794|MAK_HUMAN Serine/threonine-protein kinase MAK OS=Homo sapiens GN=MAK PE=1 SV=2	9031.ENSGALP00000020807	male germ cell-associated kinase	COG0515	KOG0661	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000020836|m.934:1-180;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000020836|m.934:1-173
ENSGALG00000012821	100.7886918	49.79966803	1.016979214	2.05E-41	5.53E-40	up	yes	105.5686482	98.3407087	98.45671843	54.15836698	44.84943875	50.39119838	2	66278012	66281874	+	TUBB2B	protein_coding	GO:0007017|microtubule-based process; GO:0031115|negative regulation of microtubule polymerization	GO:0005737|cytoplasm; GO:0005874|microtubule	GO:0003924|GTPase activity; GO:0005200|structural constituent of cytoskeleton; GO:0005509|calcium ion binding; GO:0005525|GTP binding	ko:K07375|TUBB	ko04145|Phagosome; ko04540|Gap junction; ko05130|Pathogenic Escherichia coli infection	1978	XP_015507719.1	XP_015507719.1 PREDICTED: tubulin beta-1 chain-like [Parus major]	sp|P32882|TBB2_CHICK	sp|P32882|TBB2_CHICK Tubulin beta-2 chain OS=Gallus gallus PE=1 SV=1	28377.ENSACAP00000017398	"tubulin, beta 2B"	COG5023	KOG1375	_	"PF00091.22|Tubulin|Tubulin/FtsZ family, GTPase domain|ENSGALT00000020914|m.1003:3-211;PF03953.14|Tubulin_C|Tubulin C-terminal domain|ENSGALT00000020914|m.1003:261-381"
ENSGALG00000012823	17.34817776	37.93283293	-1.128211896	1.67E-51	6.38E-50	down	yes	17.39800112	18.13483021	16.51170194	35.76377342	40.48677785	37.54794753	1	56379268	56436811	-	TRIM24	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006468|protein phosphorylation; GO:0008285|negative regulation of cell population proliferation; GO:0010628|positive regulation of gene expression; GO:0016567|protein ubiquitination; GO:0030163|protein catabolic process; GO:0031647|regulation of protein stability; GO:0042981|regulation of apoptotic process; GO:0045892|negative regulation of transcription, DNA-templated; GO:0045893|positive regulation of transcription, DNA-templated; GO:0046777|protein autophosphorylation; GO:0055074|calcium ion homeostasis; GO:0070562|regulation of vitamin D receptor signaling pathway; GO:0071391|cellular response to estrogen stimulus; GO:1901796|regulation of signal transduction by p53 class mediator"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005719|nuclear euchromatin; GO:0005726|perichromatin fibrils; GO:0005737|cytoplasm	GO:0002039|p53 binding; GO:0003682|chromatin binding; GO:0003713|transcription coactivator activity; GO:0004672|protein kinase activity; GO:0004842|ubiquitin-protein transferase activity; GO:0008270|zinc ion binding; GO:0016922|nuclear receptor binding; GO:0034056|estrogen response element binding; GO:0043565|sequence-specific DNA binding; GO:0061630|ubiquitin protein ligase activity; GO:0070577|lysine-acetylated histone binding	"ko:K08881|TRIM24,TIF1A"	--	3498	XP_015143032.1	XP_015143032.1 transcription intermediary factor 1-alpha isoform X1 [Gallus gallus]	sp|Q64127|TIF1A_MOUSE	sp|Q64127|TIF1A_MOUSE Transcription intermediary factor 1-alpha OS=Mus musculus GN=Trim24 PE=1 SV=1	9031.ENSGALP00000020886	tripartite motif-containing 24	COG5076	KOG2177	_	PF00439.22|Bromodomain|Bromodomain|ENSGALT00000020916|m.1645:1023-1104;PF00643.21|zf-B_box|B-box zinc finger|ENSGALT00000020916|m.1645:341-378;PF00628.26|PHD|PHD-finger|ENSGALT00000020916|m.1645:944-986
ENSGALG00000012875	0.37177765	0.904898184	-1.260878553	0.00013274	0.000319948	down	yes	0.407453062	0.298744939	0.409134949	0.863844483	0.996176488	0.854673579	1	57325922	57338604	+	WEE2	protein_coding	GO:0000278|mitotic cell cycle; GO:0051321|meiotic cell cycle	GO:0005634|nucleus	GO:0000287|magnesium ion binding; GO:0004715|non-membrane spanning protein tyrosine kinase activity; GO:0005524|ATP binding	ko:K06632|WEE1	ko04110|Cell cycle	2845	XP_015142823.1	XP_015142823.1 wee1-like protein kinase 2 [Gallus gallus]	sp|E1BTE1|WEE2_CHICK	sp|E1BTE1|WEE2_CHICK Wee1-like protein kinase 2 OS=Gallus gallus GN=WEE2 PE=3 SV=1	9031.ENSGALP00000020972	annotation not avaliable	COG0515	KOG0601	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000021002|m.1678:209-478;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000021002|m.1678:211-475
ENSGALG00000012913	3.804508984	34.48385915	-3.17677028	1.09E-266	1.65E-263	down	yes	3.462761276	3.926133363	4.024632312	33.58330889	35.91079619	33.95747239	1	58821965	58864004	+	PKP2	protein_coding	GO:0002159|desmosome assembly; GO:0007507|heart development; GO:0008285|negative regulation of cell population proliferation; GO:0010765|positive regulation of sodium ion transport; GO:0016264|gap junction assembly; GO:0030336|negative regulation of cell migration; GO:0031424|keratinization; GO:0034334|adherens junction maintenance; GO:0045110|intermediate filament bundle assembly; GO:0048496|maintenance of animal organ identity; GO:0055010|ventricular cardiac muscle tissue morphogenesis; GO:0055088|lipid homeostasis; GO:0070268|cornification; GO:0072659|protein localization to plasma membrane; GO:0086001|cardiac muscle cell action potential; GO:0086002|cardiac muscle cell action potential involved in contraction; GO:0086005|ventricular cardiac muscle cell action potential; GO:0086019|cell-cell signaling involved in cardiac conduction; GO:0086064|cell communication by electrical coupling involved in cardiac conduction; GO:0086073|bundle of His cell-Purkinje myocyte adhesion involved in cell communication; GO:0086091|regulation of heart rate by cardiac conduction; GO:0098609|cell-cell adhesion; GO:0098911|regulation of ventricular cardiac muscle cell action potential; GO:2000810|regulation of bicellular tight junction assembly	GO:0001533|cornified envelope; GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005882|intermediate filament; GO:0005886|plasma membrane; GO:0005911|cell-cell junction; GO:0005912|adherens junction; GO:0014704|intercalated disc; GO:0016021|integral component of membrane; GO:0030054|cell junction; GO:0030057|desmosome	GO:0005080|protein kinase C binding; GO:0017080|sodium channel regulator activity; GO:0019215|intermediate filament binding; GO:0044325|ion channel binding; GO:0045294|alpha-catenin binding; GO:0045296|cadherin binding; GO:0060090|molecular adaptor activity; GO:0086083|cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication	ko:K12642|PKP2	ko05412|Arrhythmogenic right ventricular cardiomyopathy (ARVC)	2952	XP_416362.5	XP_416362.5 plakophilin-2 [Gallus gallus]	sp|Q99959|PKP2_HUMAN	sp|Q99959|PKP2_HUMAN Plakophilin-2 OS=Homo sapiens GN=PKP2 PE=1 SV=2	9031.ENSGALP00000021029	plakophilin 2	_	KOG1048	_	PF00514.20|Arm|Armadillo/beta-catenin-like repeat|ENSGALT00000021059|m.1705:533-570;PF00514.20|Arm|Armadillo/beta-catenin-like repeat|ENSGALT00000021059|m.1705:573-614
ENSGALG00000012917	0.630059471	1.272489893	-1.002669592	0.000601637	0.001311488	down	yes	0.747391335	0.663353865	0.479433213	1.472232879	1.042345593	1.302891206	2	69267185	69363889	-	CDH6	protein_coding	GO:0007156|homophilic cell adhesion via plasma membrane adhesion molecules; GO:0007219|Notch signaling pathway	GO:0005623|cell; GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0070062|extracellular exosome	GO:0005509|calcium ion binding	ko:K06798|CDH6	--	2679	NP_001001758.1	NP_001001758.1 cadherin-6 precursor [Gallus gallus]	sp|Q90762|CADH6_CHICK	sp|Q90762|CADH6_CHICK Cadherin-6 OS=Gallus gallus GN=CDH6 PE=2 SV=1	9031.ENSGALP00000030382	Cadherin-6 Precursor (Cadherin-6B)(c-cad6B); Cadherins are calcium dependent cell adhesion p [...] 	_	KOG3594	_	PF00028.14|Cadherin|Cadherin domain|ENSGALT00000031019|m.1079:67-149;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000031019|m.1079:164-258;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000031019|m.1079:273-357;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000031019|m.1079:388-479;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000031019|m.1079:492-589;PF01049.14|Cadherin_C|Cadherin cytoplasmic region|ENSGALT00000031019|m.1079:637-783
ENSGALG00000012932	0.200156106	1.600835726	-2.938276096	4.92E-21	4.88E-20	down	yes	0.186390247	0.304860249	0.109217821	1.688041595	1.599084503	1.515381081	1	58965081	59072088	-	FGD4	protein_coding	GO:0007010|cytoskeleton organization; GO:0008360|regulation of cell shape; GO:0030036|actin cytoskeleton organization; GO:0035023|regulation of Rho protein signal transduction; GO:0043065|positive regulation of apoptotic process; GO:0043087|regulation of GTPase activity; GO:0046847|filopodium assembly; GO:0051056|regulation of small GTPase mediated signal transduction	GO:0001726|ruffle; GO:0005737|cytoplasm; GO:0005794|Golgi apparatus; GO:0005829|cytosol; GO:0005856|cytoskeleton; GO:0030027|lamellipodium; GO:0030175|filopodium	GO:0003779|actin binding; GO:0005085|guanyl-nucleotide exchange factor activity; GO:0005089|Rho guanyl-nucleotide exchange factor activity; GO:0031267|small GTPase binding; GO:0046872|metal ion binding	ko:K05723|FGD4	--	3461	XP_015142740.1	"XP_015142740.1 FYVE, RhoGEF and PH domain-containing protein 4 isoform X4 [Gallus gallus]"	sp|Q96M96|FGD4_HUMAN	"sp|Q96M96|FGD4_HUMAN FYVE, RhoGEF and PH domain-containing protein 4 OS=Homo sapiens GN=FGD4 PE=1 SV=2"	_	_	_	_	_	PF00621.17|RhoGEF|RhoGEF domain|ENSGALT00000100566|m.1713:288-469;PF00169.26|PH|PH domain|ENSGALT00000100566|m.1713:502-598;PF00169.26|PH|PH domain|ENSGALT00000100566|m.1713:736-818;PF01363.18|FYVE|FYVE zinc finger|ENSGALT00000100566|m.1713:634-696;PF16453.2|IQ_SEC7_PH|PH domain|ENSGALT00000100566|m.1713:514-604
ENSGALG00000012941	5.563784968	12.1766896	-1.128577034	4.22E-33	7.81E-32	down	yes	5.498456285	5.335772987	5.857125633	11.95041303	11.81504424	12.76461152	2	73025298	73384586	+	ENSGALG00000012941	protein_coding	GO:0007156|homophilic cell adhesion via plasma membrane adhesion molecules; GO:0034332|adherens junction organization	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0005509|calcium ion binding	ko:K06804|CDH12	--	3029	XP_025003454.1	XP_025003454.1 cadherin-12 isoform X1 [Gallus gallus]	sp|P55289|CAD12_HUMAN	sp|P55289|CAD12_HUMAN Cadherin-12 OS=Homo sapiens GN=CDH12 PE=2 SV=2	9031.ENSGALP00000021076	"cadherin 12, type 2 (N-cadherin 2)"	_	KOG3594	_	PF00028.14|Cadherin|Cadherin domain|ENSGALT00000075300|m.1089:23-109;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000075300|m.1089:123-217;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000075300|m.1089:233-334;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000075300|m.1089:347-438;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000075300|m.1089:451-548;PF01049.14|Cadherin_C|Cadherin cytoplasmic region|ENSGALT00000075300|m.1089:596-742
ENSGALG00000012944	3.236866144	11.3686145	-1.809205087	2.24E-79	1.83E-77	down	yes	3.25577042	3.100529978	3.354298033	11.45354746	11.20892768	11.44336837	1	59422545	59528716	+	DENND5B	protein_coding	GO:0050982|detection of mechanical stimulus; GO:0061024|membrane organization	GO:0005829|cytosol; GO:0016020|membrane; GO:0016021|integral component of membrane	GO:0005262|calcium channel activity; GO:0017112|Rab guanyl-nucleotide exchange factor activity	ko:K20164|DENND5	--	4008	XP_015142554.1	XP_015142554.1 DENN domain-containing protein 5B isoform X2 [Gallus gallus]	sp|Q6ZUT9|DEN5B_HUMAN	sp|Q6ZUT9|DEN5B_HUMAN DENN domain-containing protein 5B OS=Homo sapiens GN=DENND5B PE=1 SV=2	9031.ENSGALP00000021082	Putative uncharacterized protein 	_	KOG2080	_	PF02141.18|DENN|DENN (AEX-3) domain|ENSGALT00000101695|m.1731:182-369;PF02759.16|RUN|RUN domain|ENSGALT00000101695|m.1731:841-985;PF02759.16|RUN|RUN domain|ENSGALT00000101695|m.1731:1188-1323;PF03455.16|dDENN|dDENN domain|ENSGALT00000101695|m.1731:536-587;PF03456.15|uDENN|uDENN domain|ENSGALT00000101695|m.1731:53-114;PF01477.20|PLAT|PLAT/LH2 domain|ENSGALT00000101695|m.1731:999-1103
ENSGALG00000012952	6.165011323	0.781453688	2.963864944	1.77E-09	7.51E-09	up	yes	6.688062768	6.547093391	5.259877812	0.448746967	1.343998982	0.551615114	2	75358894	75406459	-	BASP1	protein_coding	"GO:0007275|multicellular organism development; GO:0045892|negative regulation of transcription, DNA-templated"	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0030426|growth cone; GO:0030863|cortical cytoskeleton; GO:0031234|extrinsic component of cytoplasmic side of plasma membrane	--	ko:K17272|BASP1	--	2346	OXB63942.1	OXB63942.1 hypothetical protein ASZ78_003559 [Callipepla squamata]	sp|P23614|BASP1_CHICK	sp|P23614|BASP1_CHICK Brain acid soluble protein 1 homolog OS=Gallus gallus GN=BASP1 PE=2 SV=4	9031.ENSGALP00000036341	"brain abundant, membrane attached signal protein 1 ; May play a specific role in the develop [...] "	_	_	NOG250087	PF05466.9|BASP1|Brain acid soluble protein 1 (BASP1 protein)|ENSGALT00000103560|m.1092:2-244
ENSGALG00000012956	5.985275787	12.22456119	-1.029064333	5.67E-25	7.06E-24	down	yes	6.243634679	5.841158751	5.87103393	11.76356618	12.24408984	12.66602755	1	59699833	59845195	+	TMTC1	protein_coding	GO:0006396|RNA processing	GO:0005739|mitochondrion; GO:0016021|integral component of membrane; GO:0042597|periplasmic space	"GO:0004553|hydrolase activity, hydrolyzing O-glycosyl compounds"	--	--	2844	XP_015142512.1	XP_015142512.1 transmembrane and TPR repeat-containing protein 1 [Gallus gallus]	sp|Q3UV71|TMTC1_MOUSE	sp|Q3UV71|TMTC1_MOUSE Transmembrane and TPR repeat-containing protein 1 OS=Mus musculus GN=Tmtc1 PE=2 SV=2	9031.ENSGALP00000021103	transmembrane and tetratricopeptide repeat containing 1	COG0457	KOG1124	_	"PF07719.14|TPR_2|Tetratricopeptide repeat|ENSGALT00000021134|m.1745:754-781;PF13414.3|TPR_11|TPR repeat|ENSGALT00000021134|m.1745:755-796;PF13414.3|TPR_11|TPR repeat|ENSGALT00000021134|m.1745:861-895;PF13181.3|TPR_8|Tetratricopeptide repeat|ENSGALT00000021134|m.1745:548-580;PF13181.3|TPR_8|Tetratricopeptide repeat|ENSGALT00000021134|m.1745:614-642;PF13181.3|TPR_8|Tetratricopeptide repeat|ENSGALT00000021134|m.1745:647-678;PF13181.3|TPR_8|Tetratricopeptide repeat|ENSGALT00000021134|m.1745:717-746;PF13181.3|TPR_8|Tetratricopeptide repeat|ENSGALT00000021134|m.1745:754-781;PF13181.3|TPR_8|Tetratricopeptide repeat|ENSGALT00000021134|m.1745:821-849;PF13181.3|TPR_8|Tetratricopeptide repeat|ENSGALT00000021134|m.1745:888-917;PF13428.3|TPR_14|Tetratricopeptide repeat|ENSGALT00000021134|m.1745:754-790;PF13432.3|TPR_16|Tetratricopeptide repeat|ENSGALT00000021134|m.1745:594-638;PF13432.3|TPR_16|Tetratricopeptide repeat|ENSGALT00000021134|m.1745:626-680;PF13432.3|TPR_16|Tetratricopeptide repeat|ENSGALT00000021134|m.1745:692-744;PF13432.3|TPR_16|Tetratricopeptide repeat|ENSGALT00000021134|m.1745:754-802;PF13432.3|TPR_16|Tetratricopeptide repeat|ENSGALT00000021134|m.1745:860-921;PF14559.3|TPR_19|Tetratricopeptide repeat|ENSGALT00000021134|m.1745:594-654;PF14559.3|TPR_19|Tetratricopeptide repeat|ENSGALT00000021134|m.1745:762-821;PF08409.8|DUF1736|Domain of unknown function (DUF1736)|ENSGALT00000021134|m.1745:358-431;PF13374.3|TPR_10|Tetratricopeptide repeat|ENSGALT00000021134|m.1745:615-640;PF13374.3|TPR_10|Tetratricopeptide repeat|ENSGALT00000021134|m.1745:717-748;PF13374.3|TPR_10|Tetratricopeptide repeat|ENSGALT00000021134|m.1745:748-777;PF13176.3|TPR_7|Tetratricopeptide repeat|ENSGALT00000021134|m.1745:718-745;PF13429.3|TPR_15|Tetratricopeptide repeat|ENSGALT00000021134|m.1745:647-810;PF12895.4|ANAPC3|Anaphase-promoting complex, cyclosome, subunit 3|ENSGALT00000021134|m.1745:730-804;PF12688.4|TPR_5|Tetratrico peptide repeat|ENSGALT00000021134|m.1745:597-666;PF07720.9|TPR_3|Tetratricopeptide repeat|ENSGALT00000021134|m.1745:754-781"
ENSGALG00000012978	11.74016838	25.7971709	-1.135090564	2.25E-30	3.62E-29	down	yes	10.64885528	12.19327182	12.37837806	25.08669272	26.39076574	25.91405424	11	15268801	15320700	+	CDYL2	protein_coding	GO:0008152|metabolic process	GO:0005634|nucleus	GO:0003824|catalytic activity; GO:0035064|methylated histone binding	ko:K00653|CDY	--	1524	XP_015148029.1	XP_015148029.1 chromodomain Y-like protein 2 [Gallus gallus]	sp|Q8N8U2|CDYL2_HUMAN	sp|Q8N8U2|CDYL2_HUMAN Chromodomain Y-like protein 2 OS=Homo sapiens GN=CDYL2 PE=1 SV=2	9031.ENSGALP00000021146	"chromodomain protein, Y-like 2"	COG1024	KOG0016;KOG1911	_	PF00378.17|ECH_1|Enoyl-CoA hydratase/isomerase|ENSGALT00000021177|m.6734:272-499;PF00385.21|Chromo|Chromo (CHRromatin Organisation MOdifier) domain|ENSGALT00000021177|m.6734:7-56;PF16113.2|ECH_2|Enoyl-CoA hydratase/isomerase|ENSGALT00000021177|m.6734:272-457
ENSGALG00000012984	0.288822165	0.1342263	1.050952903	0.009838123	0.017427656	up	yes	0.323196253	0.273993988	0.269276255	0.087378211	0.183745472	0.131555216	28	1291895	1303396	-	ENSGALG00000012984	protein_coding	GO:0015031|protein transport; GO:0016192|vesicle-mediated transport; GO:0016197|endosomal transport; GO:0032880|regulation of protein localization; GO:0045773|positive regulation of axon extension; GO:0050775|positive regulation of dendrite morphogenesis; GO:0060997|dendritic spine morphogenesis; GO:1903078|positive regulation of protein localization to plasma membrane; GO:1903543|positive regulation of exosomal secretion; GO:1905430|cellular response to glycine	GO:0005903|brush border; GO:0016459|myosin complex; GO:0032991|protein-containing complex; GO:0043005|neuron projection; GO:0043025|neuronal cell body; GO:0043197|dendritic spine; GO:0045179|apical cortex; GO:0048471|perinuclear region of cytoplasm; GO:0070062|extracellular exosome	GO:0003774|motor activity; GO:0003779|actin binding; GO:0005516|calmodulin binding; GO:0005524|ATP binding; GO:0016887|ATPase activity; GO:0017137|Rab GTPase binding; GO:0035255|ionotropic glutamate receptor binding	ko:K10357|MYO5	--	5217	XP_004948778.2	XP_004948778.2 unconventional myosin-Va [Gallus gallus]	sp|P70569|MYO5B_RAT	sp|P70569|MYO5B_RAT Unconventional myosin-Vb OS=Rattus norvegicus GN=Myo5b PE=1 SV=1	_	_	_	_	_	PF00063.18|Myosin_head|Myosin head (motor domain)|ENSGALT00000021187|m.9683:69-740;PF01843.16|DIL|DIL domain|ENSGALT00000021187|m.9683:1514-1616;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000021187|m.9683:756-775;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000021187|m.9683:779-796;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000021187|m.9683:805-823;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000021187|m.9683:827-847;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000021187|m.9683:852-871
ENSGALG00000012988	9.065948675	23.80689858	-1.391865203	6.18E-53	2.47E-51	down	yes	9.004486589	9.286466655	8.90689278	22.13970527	26.46798195	22.81300853	1	60296873	60354263	+	B4GALNT3	protein_coding	--	GO:0005794|Golgi apparatus; GO:0016021|integral component of membrane; GO:0032580|Golgi cisterna membrane; GO:0043231|intracellular membrane-bounded organelle	GO:0008376|acetylgalactosaminyltransferase activity; GO:0033842|N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity	ko:K09656|B4GALNT3	ko00513|Various types of N-glycan biosynthesis; ko01100|Metabolic pathways	3195	XP_416381.4	"XP_416381.4 beta-1,4-N-acetylgalactosaminyltransferase 3 isoform X1 [Gallus gallus]"	sp|Q6L8S8|B4GN3_MOUSE	"sp|Q6L8S8|B4GN3_MOUSE Beta-1,4-N-acetylgalactosaminyltransferase 3 OS=Mus musculus GN=B4galnt3 PE=2 SV=1"	_	_	_	_	_	PF05679.13|CHGN|Chondroitin N-acetylgalactosaminyltransferase|ENSGALT00000021202|m.1775:740-1051;PF07691.9|PA14|PA14 domain|ENSGALT00000021202|m.1775:124-269;PF02709.11|Glyco_transf_7C|N-terminal domain of galactosyltransferase|ENSGALT00000021202|m.1775:975-1050
ENSGALG00000012997	0.160006643	0.560157506	-1.745769398	6.93E-17	5.28E-16	down	yes	0.138424474	0.156353996	0.185241459	0.534753616	0.540065578	0.605653324	2	76621805	76732534	+	DNAH5	protein_coding	GO:0003341|cilium movement; GO:0007368|determination of left/right symmetry; GO:0007507|heart development; GO:0021670|lateral ventricle development; GO:0030317|flagellated sperm motility; GO:0036158|outer dynein arm assembly; GO:0060271|cilium assembly	GO:0005737|cytoplasm; GO:0005874|microtubule; GO:0005930|axoneme; GO:0036157|outer dynein arm	"GO:0003777|microtubule motor activity; GO:0005524|ATP binding; GO:0008569|ATP-dependent microtubule motor activity, minus-end-directed; GO:0045503|dynein light chain binding; GO:0045505|dynein intermediate chain binding; GO:0051959|dynein light intermediate chain binding"	ko:K10408|DNAH	ko05016|Huntington's disease	12636	XP_025003476.1	"XP_025003476.1 LOW QUALITY PROTEIN: dynein heavy chain 5, axonemal [Gallus gallus]"	sp|Q8TE73|DYH5_HUMAN	"sp|Q8TE73|DYH5_HUMAN Dynein heavy chain 5, axonemal OS=Homo sapiens GN=DNAH5 PE=1 SV=3"	9031.ENSGALP00000021191	hypothetical protein LOC776808	COG5245	KOG3595	_	"PF03028.12|Dynein_heavy|Dynein heavy chain and region D6 of dynein motor|ENSGALT00000021223|m.1119:3530-4208;PF08385.9|DHC_N1|Dynein heavy chain, N-terminal region 1|ENSGALT00000021223|m.1119:103-569;PF08393.10|DHC_N2|Dynein heavy chain, N-terminal region 2|ENSGALT00000021223|m.1119:1007-1410;PF12774.4|AAA_6|Hydrolytic ATP binding site of dynein motor region D1|ENSGALT00000021223|m.1119:1545-1776;PF12781.4|AAA_9|ATP-binding dynein motor region D5|ENSGALT00000021223|m.1119:3168-3391;PF12780.4|AAA_8|P-loop containing dynein motor region D4|ENSGALT00000021223|m.1119:2526-2789;PF12775.4|AAA_7|P-loop containing dynein motor region D3|ENSGALT00000021223|m.1119:2165-2429;PF12777.4|MT|Microtubule-binding stalk of dynein motor|ENSGALT00000021223|m.1119:2799-3140;PF07728.11|AAA_5|AAA domain (dynein-related subfamily)|ENSGALT00000021223|m.1119:1862-1995;PF07728.11|AAA_5|AAA domain (dynein-related subfamily)|ENSGALT00000021223|m.1119:2190-2328"
ENSGALG00000013001	1.1728771	3.110638729	-1.399541161	2.21E-15	1.52E-14	down	yes	1.200483227	1.018057266	1.300090808	3.422060032	3.094694218	2.815161937	2	77878228	78042678	+	CTNND2	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated; GO:0007155|cell adhesion; GO:0007165|signal transduction; GO:0016055|Wnt signaling pathway; GO:0050808|synapse organization; GO:0060828|regulation of canonical Wnt signaling pathway; GO:0060997|dendritic spine morphogenesis"	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005912|adherens junction; GO:0030425|dendrite; GO:0043204|perikaryon	GO:0008013|beta-catenin binding	--	--	2433	XP_008489561.1	XP_008489561.1 PREDICTED: catenin delta-2 [Calypte anna]	sp|Q9UQB3|CTND2_HUMAN	sp|Q9UQB3|CTND2_HUMAN Catenin delta-2 OS=Homo sapiens GN=CTNND2 PE=1 SV=3	9031.ENSGALP00000036312	PREDICTED: Gallus gallus similar to neural plakophilin-related arm-repeat protein (NPRAP) (L [...] 	_	KOG1048	_	PF00514.20|Arm|Armadillo/beta-catenin-like repeat|ENSGALT00000023413|m.1129:28-68;PF00514.20|Arm|Armadillo/beta-catenin-like repeat|ENSGALT00000023413|m.1129:78-113
ENSGALG00000013091	4.987790489	20.60079872	-2.044038085	3.97E-84	3.53E-82	down	yes	4.916063429	4.495139838	5.552168199	22.35423209	19.69057863	19.75758544	1	62935249	63064741	-	EPS8	protein_coding	GO:0008344|adult locomotory behavior; GO:0008360|regulation of cell shape; GO:0010458|exit from mitosis; GO:0016601|Rac protein signal transduction; GO:0030832|regulation of actin filament length; GO:0031532|actin cytoskeleton reorganization; GO:0036336|dendritic cell migration; GO:0048149|behavioral response to ethanol; GO:0051016|barbed-end actin filament capping; GO:0051017|actin filament bundle assembly; GO:0051764|actin crosslink formation; GO:0070358|actin polymerization-dependent cell motility; GO:1990830|cellular response to leukemia inhibitory factor	GO:0005903|brush border; GO:0005938|cell cortex; GO:0014069|postsynaptic density; GO:0017146|NMDA selective glutamate receptor complex; GO:0030054|cell junction; GO:0030426|growth cone; GO:0031982|vesicle; GO:0032420|stereocilium; GO:0032587|ruffle membrane; GO:0045202|synapse; GO:0070062|extracellular exosome	GO:0003779|actin binding; GO:0035591|signaling adaptor activity; GO:0048365|Rac GTPase binding	ko:K17277|EPS8	--	2722	XP_416405.3	XP_416405.3 epidermal growth factor receptor kinase substrate 8 isoform X1 [Gallus gallus]	sp|F1M3L7|EPS8_RAT	sp|F1M3L7|EPS8_RAT Epidermal growth factor receptor kinase substrate 8 OS=Rattus norvegicus GN=Eps8 PE=1 SV=2	_	_	_	_	_	PF08416.10|PTB|Phosphotyrosine-binding domain|ENSGALT00000100866|m.1935:64-194;PF00018.25|SH3_1|SH3 domain|ENSGALT00000100866|m.1935:540-582;PF00640.20|PID|Phosphotyrosine interaction domain (PTB/PID)|ENSGALT00000100866|m.1935:100-185;PF07653.14|SH3_2|Variant SH3 domain|ENSGALT00000100866|m.1935:537-587
ENSGALG00000013232	2.234233402	0.764322204	1.535216807	1.43E-10	6.70E-10	up	yes	2.540142094	2.159105354	2.003452758	0.744082712	0.871260686	0.677623214	25	2675996	2680461	+	RHBG	protein_coding	GO:0015695|organic cation transport; GO:0015696|ammonium transport; GO:0070634|transepithelial ammonium transport; GO:0072488|ammonium transmembrane transport	GO:0005887|integral component of plasma membrane; GO:0014731|spectrin-associated cytoskeleton; GO:0016323|basolateral plasma membrane; GO:0030659|cytoplasmic vesicle membrane; GO:0046658|anchored component of plasma membrane	GO:0008519|ammonium transmembrane transporter activity; GO:0030506|ankyrin binding	--	--	1947	NP_989698.2	NP_989698.2 ammonium transporter Rh type B [Gallus gallus]	sp|Q95M77|RHBG_BOVIN	sp|Q95M77|RHBG_BOVIN Ammonium transporter Rh type B OS=Bos taurus GN=RHBG PE=2 SV=2	9031.ENSGALP00000021577	"Rhesus blood group, B glycoprotein "	_	KOG3796	_	PF00909.18|Ammonium_transp|Ammonium Transporter Family|ENSGALT00000021610|m.6995:119-478
ENSGALG00000013234	0.688973669	0.225682874	1.568391181	0.000631852	0.001375183	up	yes	0.954644795	0.486073884	0.626202329	0.209467948	0.230730211	0.236850463	25	2672117	2674826	-	HAPLN2	protein_coding	GO:0001501|skeletal system development; GO:0007155|cell adhesion; GO:0007417|central nervous system development; GO:0008065|establishment of blood-nerve barrier; GO:0085029|extracellular matrix assembly	GO:0031012|extracellular matrix	GO:0005201|extracellular matrix structural constituent; GO:0005540|hyaluronic acid binding	ko:K06851|HAPLN2	--	1987	XP_015153905.1	XP_015153905.1 hyaluronan and proteoglycan link protein 2 isoform X1 [Gallus gallus]	sp|Q9GZV7|HPLN2_HUMAN	sp|Q9GZV7|HPLN2_HUMAN Hyaluronan and proteoglycan link protein 2 OS=Homo sapiens GN=HAPLN2 PE=2 SV=1	_	_	_	_	_	PF00193.14|Xlink|Extracellular link domain|ENSGALT00000021612|m.6993:182-275;PF00193.14|Xlink|Extracellular link domain|ENSGALT00000021612|m.6993:289-371;PF07686.14|V-set|Immunoglobulin V-set domain|ENSGALT00000021612|m.6993:77-165;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000021612|m.6993:78-165;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000021612|m.6993:77-177;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000021612|m.6993:78-170
ENSGALG00000013268	1.534842299	3.891221471	-1.33646633	3.01E-52	1.18E-50	down	yes	1.565901776	1.493108686	1.545516435	3.907862213	4.02550479	3.740297409	2	88754376	88902355	-	ENSGALG00000013268	protein_coding	GO:0003341|cilium movement; GO:0007368|determination of left/right symmetry; GO:0007507|heart development; GO:0021670|lateral ventricle development; GO:0030317|flagellated sperm motility; GO:0036158|outer dynein arm assembly; GO:0060271|cilium assembly	GO:0005737|cytoplasm; GO:0005874|microtubule; GO:0005930|axoneme; GO:0036157|outer dynein arm	"GO:0003777|microtubule motor activity; GO:0005524|ATP binding; GO:0008569|ATP-dependent microtubule motor activity, minus-end-directed; GO:0045503|dynein light chain binding; GO:0045505|dynein intermediate chain binding; GO:0051959|dynein light intermediate chain binding"	ko:K10408|DNAH	ko05016|Huntington's disease	13998	XP_015137890.2	"XP_015137890.2 dynein heavy chain 5, axonemal [Gallus gallus]"	sp|Q8TE73|DYH5_HUMAN	"sp|Q8TE73|DYH5_HUMAN Dynein heavy chain 5, axonemal OS=Homo sapiens GN=DNAH5 PE=1 SV=3"	9031.ENSGALP00000021807	annotation not avaliable	COG5245	KOG3595	_	"PF03028.12|Dynein_heavy|Dynein heavy chain and region D6 of dynein motor|ENSGALT00000021845|m.1326:3955-4654;PF08385.9|DHC_N1|Dynein heavy chain, N-terminal region 1|ENSGALT00000021845|m.1326:333-883;PF08393.10|DHC_N2|Dynein heavy chain, N-terminal region 2|ENSGALT00000021845|m.1326:1428-1833;PF12774.4|AAA_6|Hydrolytic ATP binding site of dynein motor region D1|ENSGALT00000021845|m.1326:1968-2199;PF12781.4|AAA_9|ATP-binding dynein motor region D5|ENSGALT00000021845|m.1326:3592-3816;PF12780.4|AAA_8|P-loop containing dynein motor region D4|ENSGALT00000021845|m.1326:2945-3208;PF12775.4|AAA_7|P-loop containing dynein motor region D3|ENSGALT00000021845|m.1326:2584-2848;PF12777.4|MT|Microtubule-binding stalk of dynein motor|ENSGALT00000021845|m.1326:3222-3567;PF07728.11|AAA_5|AAA domain (dynein-related subfamily)|ENSGALT00000021845|m.1326:2286-2418"
ENSGALG00000013272	5.697010048	2.307610921	1.300096715	8.07E-19	7.06E-18	up	yes	6.103053557	5.256315445	5.731661141	2.295652538	2.488131329	2.139048897	1	74873840	74925413	+	PRMT8	protein_coding	"GO:0006355|regulation of transcription, DNA-templated; GO:0016571|histone methylation; GO:0018216|peptidyl-arginine methylation; GO:0019919|peptidyl-arginine methylation, to asymmetrical-dimethyl arginine; GO:0043393|regulation of protein binding"	GO:0005829|cytosol; GO:0005886|plasma membrane	GO:0008469|histone-arginine N-methyltransferase activity; GO:0008757|S-adenosylmethionine-dependent methyltransferase activity; GO:0035241|protein-arginine omega-N monomethyltransferase activity; GO:0035242|protein-arginine omega-N asymmetric methyltransferase activity; GO:0042802|identical protein binding; GO:0042803|protein homodimerization activity; GO:0046982|protein heterodimerization activity	ko:K11439|PRMT8	--	2521	XP_015476907.1	XP_015476907.1 PREDICTED: protein arginine N-methyltransferase 8 isoform X1 [Parus major]	sp|Q9NR22|ANM8_HUMAN	sp|Q9NR22|ANM8_HUMAN Protein arginine N-methyltransferase 8 OS=Homo sapiens GN=PRMT8 PE=1 SV=2	9031.ENSGALP00000021646	protein arginine methyltransferase 8	COG0500	KOG1499	_	PF06325.10|PrmA|Ribosomal protein L11 methyltransferase (PrmA)|ENSGALT00000021680|m.2233:108-184;PF13649.3|Methyltransf_25|Methyltransferase domain|ENSGALT00000021680|m.2233:115-212;PF08241.9|Methyltransf_11|Methyltransferase domain|ENSGALT00000021680|m.2233:116-214;PF05185.13|PRMT5|PRMT5 arginine-N-methyltransferase|ENSGALT00000021680|m.2233:105-365
ENSGALG00000013420	13.12035535	6.256222202	1.067238126	3.45E-25	4.37E-24	up	yes	13.90806954	13.83360501	11.61939149	5.767002538	6.620508455	6.381155612	1	75332032	75341754	+	FOXM1	protein_coding	"GO:0000086|G2/M transition of mitotic cell cycle; GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0001570|vasculogenesis; GO:0001889|liver development; GO:0006281|DNA repair; GO:0006366|transcription by RNA polymerase II; GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; GO:0008284|positive regulation of cell population proliferation; GO:0009653|anatomical structure morphogenesis; GO:0030154|cell differentiation; GO:0032873|negative regulation of stress-activated MAPK cascade; GO:0034698|response to gonadotropin; GO:0042127|regulation of cell population proliferation; GO:0045892|negative regulation of transcription, DNA-templated; GO:0045893|positive regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0046578|regulation of Ras protein signal transduction; GO:0051591|response to cAMP; GO:0071156|regulation of cell cycle arrest; GO:0090344|negative regulation of cell aging; GO:2000377|regulation of reactive oxygen species metabolic process; GO:2000781|positive regulation of double-strand break repair"	GO:0005634|nucleus	"GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding; GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity; GO:0019901|protein kinase binding; GO:0043565|sequence-specific DNA binding; GO:0044212|transcription regulatory region DNA binding"	ko:K09406|FOXM	--	3284	XP_015148145.1	XP_015148145.1 forkhead box protein M1 isoform X2 [Gallus gallus]	sp|P97691|FOXM1_RAT	sp|P97691|FOXM1_RAT Forkhead box protein M1 OS=Rattus norvegicus GN=Foxm1 PE=2 SV=2	_	_	_	_	_	PF00250.15|Forkhead|Forkhead domain|ENSGALT00000021889|m.2248:255-335
ENSGALG00000013489	1.609371187	13.00969264	-3.007189772	5.45E-76	4.02E-74	down	yes	1.291448262	1.809613887	1.727051412	13.90398645	13.29119005	11.83390144	1	186228663	186241876	+	CCDC82	protein_coding	--	--	--	--	--	1773	XP_025002657.1	XP_025002657.1 coiled-coil domain-containing protein 82 isoform X1 [Gallus gallus]	sp|Q66H73|CCD82_RAT	sp|Q66H73|CCD82_RAT Coiled-coil domain-containing protein 82 OS=Rattus norvegicus GN=Ccdc82 PE=1 SV=1	9031.ENSGALP00000029430	coiled-coil domain containing 82	_	KOG4805	_	PF13926.3|DUF4211|Domain of unknown function (DUF4211)|ENSGALT00000101912|m.4656:235-395;PF13846.3|DUF4196|Domain of unknown function (DUF4196)|ENSGALT00000101912|m.4656:72-175
ENSGALG00000013503	3.563330339	7.74977789	-1.118746067	2.16E-19	1.95E-18	down	yes	3.002527221	4.008084862	3.679378936	7.94873234	7.56378571	7.736815622	4	61340939	61353442	+	FAM149A	protein_coding	--	--	--	--	--	3229	XP_015141055.1	XP_015141055.1 protein FAM149A isoform X2 [Gallus gallus]	sp|Q8CFV2|F149A_MOUSE	sp|Q8CFV2|F149A_MOUSE Protein FAM149A OS=Mus musculus GN=Fam149a PE=2 SV=1	9031.ENSGALP00000021955	"family with sequence similarity 149, member A"	_	_	NOG27759	PF12516.5|DUF3719|Protein of unknown function (DUF3719)|ENSGALT00000021994|m.998:102-156
ENSGALG00000013505	8.09118967	20.47505768	-1.338366265	2.21E-68	1.37E-66	down	yes	7.662229288	8.308713253	8.302626471	18.6661782	23.11336082	19.64563402	3	49258198	49530795	-	ENSGALG00000013505	protein_coding	GO:0006997|nucleus organization; GO:0007030|Golgi organization; GO:0007283|spermatogenesis; GO:0042692|muscle cell differentiation; GO:0090286|cytoskeletal anchoring at nuclear membrane; GO:0090292|nuclear matrix anchoring at nuclear membrane	GO:0000932|P-body; GO:0005634|nucleus; GO:0005635|nuclear envelope; GO:0005640|nuclear outer membrane; GO:0005654|nucleoplasm; GO:0005730|nucleolus; GO:0005737|cytoplasm; GO:0005794|Golgi apparatus; GO:0005856|cytoskeleton; GO:0016021|integral component of membrane; GO:0030017|sarcomere; GO:0031965|nuclear membrane; GO:0034993|meiotic nuclear membrane microtubule tethering complex; GO:0045211|postsynaptic membrane	GO:0003723|RNA binding; GO:0003779|actin binding; GO:0005521|lamin binding; GO:0019899|enzyme binding; GO:0042802|identical protein binding; GO:0042803|protein homodimerization activity; GO:0051015|actin filament binding	ko:K19326|SYNE1	--	25327	XP_004935689.2	XP_004935689.2 nesprin-1 isoform X1 [Gallus gallus]	sp|Q8NF91|SYNE1_HUMAN	sp|Q8NF91|SYNE1_HUMAN Nesprin-1 OS=Homo sapiens GN=SYNE1 PE=1 SV=4	9031.ENSGALP00000021957	chromosome 6 open reading frame 98	COG5069	KOG0516	_	PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000021996|m.11956:2732-2829;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000021996|m.11956:3375-3475;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000021996|m.11956:5298-5391;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000021996|m.11956:6353-6461;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000021996|m.11956:6581-6682;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000021996|m.11956:6697-6787;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000021996|m.11956:6910-7009;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000021996|m.11956:7340-7439;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000021996|m.11956:7444-7553;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000021996|m.11956:7557-7654;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000021996|m.11956:7667-7767;PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000021996|m.11956:8020-8127;PF00307.28|CH|Calponin homology (CH) domain|ENSGALT00000021996|m.11956:27-133;PF00307.28|CH|Calponin homology (CH) domain|ENSGALT00000021996|m.11956:179-282;PF10541.6|KASH|Nuclear envelope localisation domain|ENSGALT00000021996|m.11956:8320-8376
ENSGALG00000013568	42.46229052	153.3741564	-1.852555649	3.92E-103	5.20E-101	down	yes	49.38351528	39.77190242	38.23145386	155.3008659	158.1590106	146.6625927	2	89365079	89385555	-	NR4A3	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0001707|mesoderm formation; GO:0007369|gastrulation; GO:0007411|axon guidance; GO:0009444|pyruvate oxidation; GO:0010613|positive regulation of cardiac muscle hypertrophy; GO:0010828|positive regulation of glucose transmembrane transport; GO:0021766|hippocampus development; GO:0030534|adult behavior; GO:0031100|animal organ regeneration; GO:0032765|positive regulation of mast cell cytokine production; GO:0035726|common myeloid progenitor cell proliferation; GO:0038097|positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway; GO:0042472|inner ear morphogenesis; GO:0042542|response to hydrogen peroxide; GO:0043066|negative regulation of apoptotic process; GO:0043303|mast cell degranulation; GO:0043434|response to peptide hormone; GO:0043524|negative regulation of neuron apoptotic process; GO:0044320|cellular response to leptin stimulus; GO:0045333|cellular respiration; GO:0045444|fat cell differentiation; GO:0045787|positive regulation of cell cycle; GO:0045893|positive regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0046321|positive regulation of fatty acid oxidation; GO:0048660|regulation of smooth muscle cell proliferation; GO:0048661|positive regulation of smooth muscle cell proliferation; GO:0048752|semicircular canal morphogenesis; GO:0050679|positive regulation of epithelial cell proliferation; GO:0050885|neuromuscular process controlling balance; GO:0060005|vestibular reflex; GO:0061469|regulation of type B pancreatic cell proliferation; GO:0071376|cellular response to corticotropin-releasing hormone stimulus; GO:0071870|cellular response to catecholamine stimulus; GO:0097009|energy homeostasis; GO:1900625|positive regulation of monocyte aggregation; GO:1903204|negative regulation of oxidative stress-induced neuron death; GO:1903208|negative regulation of hydrogen peroxide-induced neuron death; GO:2000108|positive regulation of leukocyte apoptotic process; GO:2000253|positive regulation of feeding behavior"	GO:0005634|nucleus; GO:0005667|transcription factor complex; GO:0042629|mast cell granule	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0001046|core promoter sequence-specific DNA binding; GO:0001223|transcription coactivator binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003677|DNA binding; GO:0003707|steroid hormone receptor activity; GO:0004879|nuclear receptor activity; GO:0008270|zinc ion binding; GO:0019901|protein kinase binding; GO:0035035|histone acetyltransferase binding; GO:0035259|glucocorticoid receptor binding; GO:0042803|protein homodimerization activity; GO:0043565|sequence-specific DNA binding"	"ko:K08559|NR4A3,NOR1"	ko05202|Transcriptional misregulation in cancer	1832	XP_419081.3	XP_419081.3 nuclear receptor subfamily 4 group A member 3 isoform X2 [Gallus gallus]	sp|P51179|NR4A3_RAT	sp|P51179|NR4A3_RAT Nuclear receptor subfamily 4 group A member 3 OS=Rattus norvegicus GN=Nr4a3 PE=1 SV=1	9031.ENSGALP00000022048	"nuclear receptor subfamily 4, group A, member 3"	_	KOG4217	_	"PF00105.15|zf-C4|Zinc finger, C4 type (two domains)|ENSGALT00000022087|m.1348:269-337;PF00104.27|Hormone_recep|Ligand-binding domain of nuclear hormone receptor|ENSGALT00000022087|m.1348:411-589"
ENSGALG00000013573	68.68801162	28.13165172	1.287561335	2.93E-70	1.92E-68	up	yes	65.49174917	69.62698069	70.945305	28.26580723	28.0209813	28.10816662	2	89697618	89699292	+	ALG2	protein_coding	GO:0006488|dolichol-linked oligosaccharide biosynthetic process; GO:0033577|protein glycosylation in endoplasmic reticulum; GO:0051592|response to calcium ion	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005789|endoplasmic reticulum membrane; GO:0016020|membrane; GO:0016021|integral component of membrane; GO:0048471|perinuclear region of cytoplasm	"GO:0000033|alpha-1,3-mannosyltransferase activity; GO:0004378|GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity; GO:0046982|protein heterodimerization activity; GO:0047485|protein N-terminus binding; GO:0048306|calcium-dependent protein binding; GO:0102704|GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity"	ko:K03843|ALG2	ko00510|N-Glycan biosynthesis; ko00513|Various types of N-glycan biosynthesis; ko01100|Metabolic pathways	1239	XP_003640838.2	"XP_003640838.2 alpha-1,3/1,6-mannosyltransferase ALG2 [Gallus gallus]"	sp|Q9H553|ALG2_HUMAN	"sp|Q9H553|ALG2_HUMAN Alpha-1,3/1,6-mannosyltransferase ALG2 OS=Homo sapiens GN=ALG2 PE=1 SV=1"	9031.ENSGALP00000022055	"PREDICTED: Gallus gallus hypothetical LOC420998 (LOC420998), mRNA"	COG0438	KOG0853	_	PF00534.17|Glycos_transf_1|Glycosyl transferases group 1|ENSGALT00000022094|m.1350:217-387;PF13692.3|Glyco_trans_1_4|Glycosyl transferases group 1|ENSGALT00000022094|m.1350:223-375;PF13439.3|Glyco_transf_4|Glycosyltransferase Family 4|ENSGALT00000022094|m.1350:25-187;PF13579.3|Glyco_trans_4_4|Glycosyl transferase 4-like domain|ENSGALT00000022094|m.1350:25-178
ENSGALG00000013575	1.689688109	0.119448756	3.714817028	3.01E-18	2.53E-17	up	yes	1.897908582	1.627403851	1.543751895	0.133099044	0.165389946	0.059857279	2	89717661	89722211	+	IFI6	protein_coding	--	--	--	--	--	1638	ACD63046.1	ACD63046.1 putative ISG12(2) [Anas platyrhynchos]	_	_	9031.ENSGALP00000022057	putative ISG12-2 protein 	_	_	NOG240426	PF06140.10|Ifi-6-16|Interferon-induced 6-16 family|ENSGALT00000022096|m.1353:11-60;PF06140.10|Ifi-6-16|Interferon-induced 6-16 family|ENSGALT00000022096|m.1353:63-107
ENSGALG00000013576	0.130825682	1.419518686	-3.343547113	2.47E-07	8.45E-07	down	yes	0.247376005	0.145101041	0	1.004940391	1.780620767	1.472994901	4	61619295	61668372	-	MTNR1A	protein_coding	GO:0007623|circadian rhythm; GO:0045820|negative regulation of glycolytic process; GO:0046325|negative regulation of glucose import	GO:0005887|integral component of plasma membrane; GO:0043235|receptor complex	GO:0008502|melatonin receptor activity; GO:0042562|hormone binding; GO:1904408|melatonin binding	ko:K04285|MTNR1A	ko04080|Neuroactive ligand-receptor interaction; ko04713|Circadian entrainment	1065	NP_990693.1	NP_990693.1 melatonin receptor type 1A [Gallus gallus]	sp|P49285|MTR1A_CHICK	sp|P49285|MTR1A_CHICK Melatonin receptor type 1A OS=Gallus gallus PE=2 SV=1	9031.ENSGALP00000022058	Melatonin receptor type 1A (MEL-1A-R)(CKA); High affinity receptor for melatonin. The activi [...] 	_	KOG3656	_	PF00001.18|7tm_1|7 transmembrane receptor (rhodopsin family)|ENSGALT00000022097|m.1001:48-299;PF10328.6|7TM_GPCR_Srx|Serpentine type 7TM GPCR chemoreceptor Srx|ENSGALT00000022097|m.1001:41-312;PF10320.6|7TM_GPCR_Srsx|Serpentine type 7TM GPCR chemoreceptor Srsx|ENSGALT00000022097|m.1001:43-313
ENSGALG00000013607	11.40262352	3.383289764	1.749873938	2.04E-47	6.74E-46	up	yes	10.93225971	11.41554158	11.86006928	3.127041297	3.696499223	3.326328772	3	49696705	49702902	-	FBXO5	protein_coding	GO:0000083|regulation of transcription involved in G1/S transition of mitotic cell cycle; GO:0001556|oocyte maturation; GO:0007057|spindle assembly involved in female meiosis I; GO:0007088|regulation of mitotic nuclear division; GO:0007346|regulation of mitotic cell cycle; GO:0016050|vesicle organization; GO:0045835|negative regulation of meiotic nuclear division; GO:0046785|microtubule polymerization; GO:0051301|cell division; GO:1904668|positive regulation of ubiquitin protein ligase activity	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005819|spindle; GO:0005829|cytosol	GO:0019901|protein kinase binding; GO:0046872|metal ion binding; GO:1990948|ubiquitin ligase inhibitor activity	"ko:K10292|FBXO5,EMI1"	ko04114|Oocyte meiosis	2193	XP_015139743.1	XP_015139743.1 F-box only protein 5 [Gallus gallus]	sp|Q9UKT4|FBX5_HUMAN	sp|Q9UKT4|FBX5_HUMAN F-box only protein 5 OS=Homo sapiens GN=FBXO5 PE=1 SV=1	_	_	_	_	_	PF00646.30|F-box|F-box domain|ENSGALT00000022138|m.11967:253-284
ENSGALG00000013624	13.29372482	50.23994075	-1.917291663	1.18E-181	7.53E-179	down	yes	12.67990606	12.97747888	14.22378951	47.99251546	52.59073145	50.13657533	2	90145304	90201328	+	FAM65B	protein_coding	GO:0006935|chemotaxis; GO:0007155|cell adhesion; GO:0007162|negative regulation of cell adhesion; GO:0007605|sensory perception of sound; GO:0035024|negative regulation of Rho protein signal transduction; GO:0045663|positive regulation of myoblast differentiation; GO:0048741|skeletal muscle fiber development; GO:0051491|positive regulation of filopodium assembly; GO:0090023|positive regulation of neutrophil chemotaxis; GO:1901741|positive regulation of myoblast fusion; GO:1903904|negative regulation of establishment of T cell polarity; GO:1905872|negative regulation of protein localization to cell leading edge; GO:1990869|cellular response to chemokine; GO:2000114|regulation of establishment of cell polarity; GO:2000391|positive regulation of neutrophil extravasation; GO:2000405|negative regulation of T cell migration; GO:2001107|negative regulation of Rho guanyl-nucleotide exchange factor activity	GO:0005737|cytoplasm; GO:0005856|cytoskeleton; GO:0016324|apical plasma membrane; GO:0030175|filopodium; GO:0032420|stereocilium; GO:0060171|stereocilium membrane	GO:0071889|14-3-3 protein binding	--	--	4537	NP_001012883.1	NP_001012883.1 rho family-interacting cell polarization regulator 2 [Gallus gallus]	sp|Q5F3L9|RIPR2_CHICK	sp|Q5F3L9|RIPR2_CHICK Rho family-interacting cell polarization regulator 2 OS=Gallus gallus GN=RIPOR2 PE=2 SV=1	9031.ENSGALP00000022126	Protein FAM65B (Myogenesis-related and NCAM-associated protein)(MYONAP); May influence the f [...] 	_	_	NOG86786	"PF15903.2|PL48|Filopodia upregulated, FAM65|ENSGALT00000022165|m.1372:16-361"
ENSGALG00000013625	1.294821397	4.022963712	-1.627988079	5.83E-12	3.05E-11	down	yes	1.222381798	1.485890473	1.17619192	4.670566467	3.447744252	3.950580417	3	50167911	50232264	-	ENSGALG00000013625	protein_coding	GO:0006979|response to oxidative stress; GO:0015671|oxygen transport	GO:0005829|cytosol; GO:0005886|plasma membrane	GO:0004601|peroxidase activity; GO:0005344|oxygen carrier activity; GO:0019904|protein domain specific binding	--	--	1554	XP_419684.3	XP_419684.3 interactor protein for cytohesin exchange factors 1 isoform X1 [Gallus gallus]	sp|Q8WWN9|ICEF1_HUMAN	sp|Q8WWN9|ICEF1_HUMAN Interactor protein for cytohesin exchange factors 1 OS=Homo sapiens GN=IPCEF1 PE=1 SV=1	9031.ENSGALP00000022129	interaction protein for cytohesin exchange factors 1	_	KOG1738	_	PF00169.26|PH|PH domain|ENSGALT00000099240|m.11972:40-135
ENSGALG00000013632	90.49657381	29.30822865	1.626224643	1.84E-75	1.32E-73	up	yes	83.50847681	98.36277864	89.61846597	31.02708781	30.46030423	26.43729391	2	90236164	90240896	-	ACOT13	protein_coding	GO:0051289|protein homotetramerization	GO:0005634|nucleus; GO:0005739|mitochondrion; GO:0005819|spindle; GO:0005829|cytosol; GO:0070062|extracellular exosome	GO:0047617|acyl-CoA hydrolase activity	ko:K17362|ACOT13	--	1031	XP_015137900.1	XP_015137900.1 acyl-coenzyme A thioesterase 13 [Gallus gallus]	sp|Q9CQR4|ACO13_MOUSE	sp|Q9CQR4|ACO13_MOUSE Acyl-coenzyme A thioesterase 13 OS=Mus musculus GN=Acot13 PE=1 SV=1	59729.ENSTGUP00000009303	Thioesterase superfamily member 2 [Taeniopygia guttata]	COG2050	KOG3328	_	PF03061.19|4HBT|Thioesterase superfamily|ENSGALT00000086884|m.1378:56-130
ENSGALG00000013715	0.935955634	3.013514908	-1.676382266	2.37E-29	3.58E-28	down	yes	0.901875386	0.912820529	0.993170987	3.123209316	2.841876205	3.075459202	4	64370643	64586585	+	DLC1	protein_coding	GO:0001843|neural tube closure; GO:0003007|heart morphogenesis; GO:0006915|apoptotic process; GO:0006919|activation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0007165|signal transduction; GO:0008285|negative regulation of cell population proliferation; GO:0008360|regulation of cell shape; GO:0021575|hindbrain morphogenesis; GO:0030036|actin cytoskeleton organization; GO:0030336|negative regulation of cell migration; GO:0030900|forebrain development; GO:0032956|regulation of actin cytoskeleton organization; GO:0035024|negative regulation of Rho protein signal transduction; GO:0035307|positive regulation of protein dephosphorylation; GO:0048041|focal adhesion assembly; GO:0051056|regulation of small GTPase mediated signal transduction; GO:0051497|negative regulation of stress fiber assembly; GO:0051895|negative regulation of focal adhesion assembly; GO:1900119|positive regulation of execution phase of apoptosis	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005901|caveola; GO:0005925|focal adhesion; GO:0030864|cortical actin cytoskeleton; GO:0032587|ruffle membrane	GO:0005096|GTPase activator activity; GO:0008289|lipid binding; GO:0042169|SH2 domain binding	ko:K20632|DLC	--	5142	XP_420693.3	XP_420693.3 rho GTPase-activating protein 7 isoform X1 [Gallus gallus]	sp|Q96QB1|RHG07_HUMAN	sp|Q96QB1|RHG07_HUMAN Rho GTPase-activating protein 7 OS=Homo sapiens GN=DLC1 PE=1 SV=4	_	_	_	_	_	PF01852.16|START|START domain|ENSGALT00000050929|m.1055:1330-1523;PF00620.24|RhoGAP|RhoGAP domain|ENSGALT00000050929|m.1055:1095-1239;PF07647.14|SAM_2|SAM domain (Sterile alpha motif)|ENSGALT00000050929|m.1055:455-514
ENSGALG00000013722	1.194979888	0.586883016	1.013488958	0.000839705	0.001786924	up	yes	1.360388119	0.969340912	1.255210632	0.641436195	0.719897327	0.399315527	12	3631598	3635036	+	ENSGALG00000013722	protein_coding	GO:0007267|cell-cell signaling; GO:0007411|axon guidance; GO:0050919|negative chemotaxis	GO:0005615|extracellular space; GO:0005783|endoplasmic reticulum; GO:0070062|extracellular exosome	GO:0038191|neuropilin binding	ko:K06840|SEMA3	ko04360|Axon guidance	2750	XP_025010280.1	XP_025010280.1 semaphorin-3B isoform X1 [Gallus gallus]	sp|Q13214|SEM3B_HUMAN	sp|Q13214|SEM3B_HUMAN Semaphorin-3B OS=Homo sapiens GN=SEMA3B PE=2 SV=1	59729.ENSTGUP00000006746	Semaphorin-3B Precursor (Semaphorin V)(Sema V)(Sema A(V)) [Taeniopygia guttata]	_	KOG3611	_	PF01403.16|Sema|Sema domain|ENSGALT00000062751|m.7393:21-417
ENSGALG00000013723	2.575371518	5.560485313	-1.107431413	1.64E-09	6.98E-09	down	yes	2.84909472	2.340640497	2.536379335	5.758675789	5.634032742	5.288747408	12	3635427	3637460	-	OASL	protein_coding	GO:0009615|response to virus; GO:0045071|negative regulation of viral genome replication; GO:0045087|innate immune response; GO:0051607|defense response to virus; GO:0060700|regulation of ribonuclease activity	GO:0005615|extracellular space; GO:0005634|nucleus; GO:0005737|cytoplasm	GO:0001730|2'-5'-oligoadenylate synthetase activity; GO:0003725|double-stranded RNA binding; GO:0005524|ATP binding; GO:0046872|metal ion binding	ko:K14608|OASL	--	1535	XP_015148492.1	XP_015148492.1 59 kDa 2'-5'-oligoadenylate synthase-like protein isoform X1 [Gallus gallus]	sp|Q5MYT7|OAS3_RAT	sp|Q5MYT7|OAS3_RAT 2'-5'-oligoadenylate synthase 3 OS=Rattus norvegicus GN=Oas3 PE=2 SV=1	9031.ENSGALP00000035092	2'-5'-oligoadenylate synthetase-like 	COG5272	KOG0001	NOG124087;NOG48070	"PF10421.6|OAS1_C|2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus|ENSGALT00000029324|m.7396:170-346;PF00240.20|ubiquitin|Ubiquitin family|ENSGALT00000029324|m.7396:402-471;PF11976.5|Rad60-SLD|Ubiquitin-2 like Rad60 SUMO-like|ENSGALT00000029324|m.7396:402-464;PF01909.20|NTP_transf_2|Nucleotidyltransferase domain|ENSGALT00000029324|m.7396:44-101;PF14560.3|Ubiquitin_2|Ubiquitin-like domain|ENSGALT00000029324|m.7396:413-464"
ENSGALG00000013725	7.006966628	16.15917653	-1.2043268	2.67E-24	3.19E-23	down	yes	5.616935904	7.61634849	7.787615492	15.7001392	15.94072853	16.83666186	4	64714109	64728848	+	LONRF1	protein_coding	GO:0000209|protein polyubiquitination; GO:0032436|positive regulation of proteasomal ubiquitin-dependent protein catabolic process	GO:0005622|intracellular; GO:0005829|cytosol	GO:0004842|ubiquitin-protein transferase activity; GO:0031624|ubiquitin conjugating enzyme binding; GO:0046872|metal ion binding; GO:0061630|ubiquitin protein ligase activity	--	--	2242	XP_420695.4	XP_420695.4 LON peptidase N-terminal domain and RING finger protein 1 [Gallus gallus]	sp|Q17RB8|LONF1_HUMAN	sp|Q17RB8|LONF1_HUMAN LON peptidase N-terminal domain and RING finger protein 1 OS=Homo sapiens GN=LONRF1 PE=1 SV=2	9031.ENSGALP00000022268	LON peptidase N-terminal domain and ring finger 1	COG2802	KOG4159	_	"PF02190.13|LON_substr_bdg|ATP-dependent protease La (LON) substrate-binding domain|ENSGALT00000022307|m.1061:319-515;PF13923.3|zf-C3HC4_2|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000022307|m.1061:229-267;PF13920.3|zf-C3HC4_3|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000022307|m.1061:227-272;PF13445.3|zf-RING_UBOX|RING-type zinc-finger|ENSGALT00000022307|m.1061:230-265;PF00097.22|zf-C3HC4|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000022307|m.1061:230-267;PF13639.3|zf-RING_2|Ring finger domain|ENSGALT00000022307|m.1061:229-268"
ENSGALG00000013727	3.486625553	9.698122345	-1.473228981	6.64E-38	1.53E-36	down	yes	3.543346251	3.383421738	3.533108671	9.121647647	11.20638818	8.766331206	3	51874584	51938032	+	SYNJ2	protein_coding	GO:0006661|phosphatidylinositol biosynthetic process; GO:0046856|phosphatidylinositol dephosphorylation; GO:0061024|membrane organization	GO:0005829|cytosol; GO:0005856|cytoskeleton; GO:0005886|plasma membrane; GO:0030424|axon; GO:0045121|membrane raft	"GO:0003723|RNA binding; GO:0004438|phosphatidylinositol-3-phosphatase activity; GO:0004439|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; GO:0034596|phosphatidylinositol phosphate 4-phosphatase activity; GO:0043813|phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; GO:0052629|phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity"	ko:K20279|SYNJ	ko00562|Inositol phosphate metabolism; ko01100|Metabolic pathways; ko04070|Phosphatidylinositol signaling system	4476	XP_003640964.1	XP_003640964.1 synaptojanin-2 isoform X1 [Gallus gallus]	sp|O15056|SYNJ2_HUMAN	sp|O15056|SYNJ2_HUMAN Synaptojanin-2 OS=Homo sapiens GN=SYNJ2 PE=1 SV=3	9031.ENSGALP00000022272	annotation not avaliable	COG5329;COG5411	KOG0566	_	PF02383.15|Syja_N|SacI homology domain|ENSGALT00000022311|m.11994:59-338;PF08952.8|DUF1866|Domain of unknown function (DUF1866)|ENSGALT00000022311|m.11994:862-1007;PF03372.20|Exo_endo_phos|Endonuclease/Exonuclease/phosphatase family|ENSGALT00000022311|m.11994:533-854
ENSGALG00000013733	58.41685175	25.60703057	1.1895283	7.85E-48	2.66E-46	up	yes	53.02622677	62.74133143	59.48299704	24.48393051	26.2145986	26.12256262	3	51964607	51969192	+	GTF2H5	protein_coding	"GO:0006281|DNA repair; GO:0006289|nucleotide-excision repair; GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated"	GO:0000439|transcription factor TFIIH core complex; GO:0005654|nucleoplasm	--	"ko:K10845|TTDA,GTF2H5,TFB5"	ko03022|Basal transcription factors; ko03420|Nucleotide excision repair	1381	OPJ72950.1	OPJ72950.1 general transcription factor IIH subunit 5 [Patagioenas fasciata monilis]	sp|Q5ZKH0|TF2H5_CHICK	sp|Q5ZKH0|TF2H5_CHICK General transcription factor IIH subunit 5 OS=Gallus gallus GN=GTF2H5 PE=3 SV=1	9031.ENSGALP00000022280	General transcription factor IIH subunit 5 (General transcription factor IIH polypeptide 5)( [...] 	_	KOG3451	_	_
ENSGALG00000013741	0.732892275	0.30069391	1.25765906	0.000230575	0.000535159	up	yes	0.690972587	0.792408302	0.715295935	0.266572397	0.266270027	0.369239307	3	52171021	52200623	+	SYTL3	protein_coding	GO:0006886|intracellular protein transport; GO:0006906|vesicle fusion; GO:0017158|regulation of calcium ion-dependent exocytosis; GO:0048791|calcium ion-regulated exocytosis of neurotransmitter	GO:0005886|plasma membrane; GO:0019897|extrinsic component of plasma membrane; GO:0070382|exocytic vesicle; GO:0098793|presynapse	GO:0005509|calcium ion binding; GO:0005544|calcium-dependent phospholipid binding; GO:0017137|Rab GTPase binding; GO:0019905|syntaxin binding; GO:0030276|clathrin binding; GO:0042043|neurexin family protein binding	ko:K17598|SYTL	--	2974	XP_015139696.1	XP_015139696.1 synaptotagmin-like protein 3 [Gallus gallus]	sp|Q4VX76|SYTL3_HUMAN	sp|Q4VX76|SYTL3_HUMAN Synaptotagmin-like protein 3 OS=Homo sapiens GN=SYTL3 PE=2 SV=3	_	_	_	_	_	PF00168.27|C2|C2 domain|ENSGALT00000102724|m.12002:321-432;PF00168.27|C2|C2 domain|ENSGALT00000102724|m.12002:483-578;PF02318.13|FYVE_2|FYVE-type zinc finger|ENSGALT00000102724|m.12002:10-122
ENSGALG00000013771	2.75827252	7.415586983	-1.423519099	4.43E-36	9.22E-35	down	yes	3.034622492	2.521119323	2.719075743	7.255300427	6.9032057	8.088254823	4	64810015	64867065	-	KIAA1211	protein_coding	--	--	--	--	--	4686	XP_015717707.1	XP_015717707.1 PREDICTED: uncharacterized protein KIAA1211 homolog isoform X1 [Coturnix japonica]	sp|Q5PR69|K1211_MOUSE	sp|Q5PR69|K1211_MOUSE Uncharacterized protein KIAA1211 OS=Mus musculus GN=Kiaa1211 PE=1 SV=3	9031.ENSGALP00000022326	annotation not avaliable	_	_	NOG77421	PF15262.3|DUF4592|Domain of unknown function (DUF4592)|ENSGALT00000096194|m.1071:201-327
ENSGALG00000013826	3.61367564	1.043283496	1.782560028	3.54E-06	1.06E-05	up	yes	2.544740099	5.103527221	3.192759601	1.435799067	0.858430201	0.835621219	3	54176664	54179502	-	ABRACL	protein_coding	--	--	--	--	--	704	XP_021248249.1	XP_021248249.1 costars family protein ABRACL [Numida meleagris]	sp|Q6V289|ABRAL_COTCO	sp|Q6V289|ABRAL_COTCO Costars family protein ABRACL OS=Coturnix coturnix PE=3 SV=2	9031.ENSGALP00000022400	chromosome 6 open reading frame 115	_	KOG3376	_	_
ENSGALG00000013838	0.639311645	0.250410197	1.318125142	0.004789013	0.008999322	up	yes	0.435463546	0.48732554	0.99514585	0.155177833	0.271933012	0.324119746	5	27660750	27663048	+	ADAM20	protein_coding	GO:0007338|single fertilization; GO:0007339|binding of sperm to zona pellucida	GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0019031|viral envelope	GO:0004222|metalloendopeptidase activity; GO:0008237|metallopeptidase activity; GO:0046872|metal ion binding	ko:K08610|ADAM21	--	2299	NP_001264719.3	NP_001264719.3 disintegrin and metalloproteinase domain-containing protein 21-like precursor [Gallus gallus]	sp|O43506|ADA20_HUMAN	sp|O43506|ADA20_HUMAN Disintegrin and metalloproteinase domain-containing protein 20 OS=Homo sapiens GN=ADAM20 PE=2 SV=2	9031.ENSGALP00000022413	synaptojanin 2 binding protein	_	KOG3607	_	PF01421.16|Reprolysin|Reprolysin (M12B) family zinc metalloprotease|ENSGALT00000022453|m.3190:198-390;PF08516.9|ADAM_CR|ADAM cysteine-rich|ENSGALT00000022453|m.3190:486-594;PF01562.16|Pep_M12B_propep|Reprolysin family propeptide|ENSGALT00000022453|m.3190:43-149;PF00200.20|Disintegrin|Disintegrin|ENSGALT00000022453|m.3190:409-481;PF13688.3|Reprolysin_5|Metallo-peptidase family M12|ENSGALT00000022453|m.3190:197-368;PF13582.3|Reprolysin_3|Metallo-peptidase family M12B Reprolysin-like|ENSGALT00000022453|m.3190:224-344;PF13574.3|Reprolysin_2|Metallo-peptidase family M12B Reprolysin-like|ENSGALT00000022453|m.3190:222-378;PF13583.3|Reprolysin_4|Metallo-peptidase family M12B Reprolysin-like|ENSGALT00000022453|m.3190:198-364
ENSGALG00000013861	2.918855816	32.64170955	-3.478749451	2.76E-231	2.78E-228	down	yes	3.255464179	2.544982618	2.95612065	30.77561415	33.87638135	33.27313315	3	54664503	54683327	-	TNFAIP3	protein_coding	GO:0001922|B-1 B cell homeostasis; GO:0002237|response to molecule of bacterial origin; GO:0002315|marginal zone B cell differentiation; GO:0002632|negative regulation of granuloma formation; GO:0002634|regulation of germinal center formation; GO:0002637|regulation of immunoglobulin production; GO:0002677|negative regulation of chronic inflammatory response; GO:0006915|apoptotic process; GO:0006954|inflammatory response; GO:0009611|response to wounding; GO:0010507|negative regulation of autophagy; GO:0016579|protein deubiquitination; GO:0031397|negative regulation of protein ubiquitination; GO:0032088|negative regulation of NF-kappaB transcription factor activity; GO:0032495|response to muramyl dipeptide; GO:0032691|negative regulation of interleukin-1 beta production; GO:0032703|negative regulation of interleukin-2 production; GO:0032715|negative regulation of interleukin-6 production; GO:0032720|negative regulation of tumor necrosis factor production; GO:0034115|negative regulation of heterotypic cell-cell adhesion; GO:0034140|negative regulation of toll-like receptor 3 signaling pathway; GO:0034148|negative regulation of toll-like receptor 5 signaling pathway; GO:0035871|protein K11-linked deubiquitination; GO:0043124|negative regulation of I-kappaB kinase/NF-kappaB signaling; GO:0045088|regulation of innate immune response; GO:0045732|positive regulation of protein catabolic process; GO:0045736|negative regulation of cyclin-dependent protein serine/threonine kinase activity; GO:0045824|negative regulation of innate immune response; GO:0048662|negative regulation of smooth muscle cell proliferation; GO:0050728|negative regulation of inflammatory response; GO:0050869|negative regulation of B cell activation; GO:0060548|negative regulation of cell death; GO:0070301|cellular response to hydrogen peroxide; GO:0070429|negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway; GO:0070433|negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway; GO:0070536|protein K63-linked deubiquitination; GO:0070936|protein K48-linked ubiquitination; GO:0071108|protein K48-linked deubiquitination; GO:0071222|cellular response to lipopolysaccharide; GO:0071947|protein deubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0072573|tolerance induction to lipopolysaccharide; GO:0072666|establishment of protein localization to vacuole; GO:1902042|negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; GO:1903364|positive regulation of cellular protein catabolic process; GO:2000347|positive regulation of hepatocyte proliferation; GO:2000349|negative regulation of CD40 signaling pathway; GO:2000352|negative regulation of endothelial cell apoptotic process	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005764|lysosome; GO:0070062|extracellular exosome	GO:0002020|protease binding; GO:0003677|DNA binding; GO:0004842|ubiquitin-protein transferase activity; GO:0004843|thiol-dependent ubiquitin-specific protease activity; GO:0008270|zinc ion binding; GO:0016874|ligase activity; GO:0019900|kinase binding; GO:0036459|thiol-dependent ubiquitinyl hydrolase activity; GO:0042802|identical protein binding; GO:0043130|ubiquitin binding; GO:0043621|protein self-association; GO:0061578|Lys63-specific deubiquitinase activity; GO:0070530|K63-linked polyubiquitin modification-dependent protein binding	"ko:K11859|TNFAIP3,A20,OTUD7C"	ko04064|NF-kappa B signaling pathway; ko04621|NOD-like receptor signaling pathway; ko04657|IL-17 signaling pathway; ko04668|TNF signaling pathway; ko05162|Measles; ko05169|Epstein-Barr virus infection	2436	XP_015139672.1	XP_015139672.1 tumor necrosis factor alpha-induced protein 3 [Gallus gallus]	sp|Q60769|TNAP3_MOUSE	sp|Q60769|TNAP3_MOUSE Tumor necrosis factor alpha-induced protein 3 OS=Mus musculus GN=Tnfaip3 PE=1 SV=2	9031.ENSGALP00000022443	"PREDICTED: Gallus gallus similar to Tumor necrosis factor, alpha-induced protein 3 (Putative [...] "	_	KOG4345	_	PF01754.13|zf-A20|A20-like zinc finger|ENSGALT00000062647|m.12076:392-414;PF01754.13|zf-A20|A20-like zinc finger|ENSGALT00000062647|m.12076:481-505;PF01754.13|zf-A20|A20-like zinc finger|ENSGALT00000062647|m.12076:611-633;PF01754.13|zf-A20|A20-like zinc finger|ENSGALT00000062647|m.12076:781-805;PF02338.16|OTU|OTU-like cysteine protease|ENSGALT00000062647|m.12076:104-263
ENSGALG00000013869	4.224221905	16.49100534	-1.962385141	1.58E-47	5.27E-46	down	yes	3.358378997	5.230616819	4.083669898	15.55913746	18.37242658	15.54145199	3	54956242	54977305	+	IL20RA	protein_coding	GO:0019221|cytokine-mediated signaling pathway; GO:0045124|regulation of bone resorption; GO:2001244|positive regulation of intrinsic apoptotic signaling pathway	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0004896|cytokine receptor activity; GO:0042015|interleukin-20 binding	ko:K05136|IL20RA	ko04060|Cytokine-cytokine receptor interaction; ko04630|Jak-STAT signaling pathway	2378	XP_419723.1	XP_419723.1 interleukin-20 receptor subunit alpha isoform X1 [Gallus gallus]	sp|Q9UHF4|I20RA_HUMAN	sp|Q9UHF4|I20RA_HUMAN Interleukin-20 receptor subunit alpha OS=Homo sapiens GN=IL20RA PE=1 SV=2	9031.ENSGALP00000022453	"interleukin 20 receptor, alpha"	_	_	NOG25594	"PF01108.14|Tissue_fac|Tissue factor|ENSGALT00000092514|m.12085:117-201;PF09294.7|Interfer-bind|Interferon-alpha/beta receptor, fibronectin type III|ENSGALT00000092514|m.12085:213-317"
ENSGALG00000013882	11.46436302	4.580608427	1.321656784	2.28E-36	4.86E-35	up	yes	11.57407073	11.30513759	11.51388073	5.178556501	3.960898428	4.602370351	22	4110333	4118011	+	MXD1	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006351|transcription, DNA-templated; GO:0007275|multicellular organism development; GO:0008283|cell population proliferation"	GO:0000790|nuclear chromatin; GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005739|mitochondrion; GO:0005829|cytosol	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0001227|DNA-binding transcription repressor activity, RNA polymerase II-specific; GO:0003700|DNA-binding transcription factor activity; GO:0003712|transcription coregulator activity; GO:0003714|transcription corepressor activity; GO:0046983|protein dimerization activity"	"ko:K09114|MXD,MAD"	--	3988	NP_001034399.1	NP_001034399.1 max dimerization protein 1 [Gallus gallus]	sp|Q05195|MAD1_HUMAN	sp|Q05195|MAD1_HUMAN Max dimerization protein 1 OS=Homo sapiens GN=MXD1 PE=1 SV=1	_	_	_	_	_	PF00010.23|HLH|Helix-loop-helix DNA-binding domain|ENSGALT00000022511|m.4993:110-161
ENSGALG00000013892	23.52830383	52.32954139	-1.15289092	8.76E-77	6.62E-75	down	yes	22.44408881	23.43451183	24.70631084	50.29097034	53.4543265	53.24332733	3	55054006	55149738	+	MAP3K5	protein_coding	"GO:0000165|MAPK cascade; GO:0000186|activation of MAPKK activity; GO:0000187|activation of MAPK activity; GO:0002931|response to ischemia; GO:0006468|protein phosphorylation; GO:0007254|JNK cascade; GO:0008631|intrinsic apoptotic signaling pathway in response to oxidative stress; GO:0010666|positive regulation of cardiac muscle cell apoptotic process; GO:0010941|regulation of cell death; GO:0034198|cellular response to amino acid starvation; GO:0034976|response to endoplasmic reticulum stress; GO:0038066|p38MAPK cascade; GO:0042060|wound healing; GO:0043065|positive regulation of apoptotic process; GO:0043280|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0043507|positive regulation of JUN kinase activity; GO:0045087|innate immune response; GO:0045663|positive regulation of myoblast differentiation; GO:0045893|positive regulation of transcription, DNA-templated; GO:0046330|positive regulation of JNK cascade; GO:0051403|stress-activated MAPK cascade; GO:0070059|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; GO:0070301|cellular response to hydrogen peroxide; GO:0071356|cellular response to tumor necrosis factor; GO:0072577|endothelial cell apoptotic process; GO:0097300|programmed necrotic cell death; GO:1900745|positive regulation of p38MAPK cascade; GO:1901216|positive regulation of neuron death; GO:1902170|cellular response to reactive nitrogen species; GO:1904707|positive regulation of vascular smooth muscle cell proliferation"	GO:0005829|cytosol; GO:0009897|external side of plasma membrane; GO:0032991|protein-containing complex; GO:1902911|protein kinase complex; GO:1990604|IRE1-TRAF2-ASK1 complex	GO:0000287|magnesium ion binding; GO:0004672|protein kinase activity; GO:0004709|MAP kinase kinase kinase activity; GO:0005524|ATP binding; GO:0019901|protein kinase binding; GO:0019903|protein phosphatase binding; GO:0019904|protein domain specific binding; GO:0042803|protein homodimerization activity	"ko:K04426|MAP3K5,ASK1"	ko01524|Platinum drug resistance; ko04010|MAPK signaling pathway; ko04013|MAPK signaling pathway - fly; ko04071|Sphingolipid signaling pathway; ko04141|Protein processing in endoplasmic reticulum; ko04210|Apoptosis; ko04214|Apoptosis - fly; ko04530|Tight junction; ko04668|TNF signaling pathway; ko04722|Neurotrophin signaling pathway; ko04932|Non-alcoholic fatty liver disease (NAFLD); ko05014|Amyotrophic lateral sclerosis (ALS); ko05418|Fluid shear stress and atherosclerosis	4852	XP_015139670.1	XP_015139670.1 mitogen-activated protein kinase kinase kinase 5 [Gallus gallus]	sp|O35099|M3K5_MOUSE	sp|O35099|M3K5_MOUSE Mitogen-activated protein kinase kinase kinase 5 OS=Mus musculus GN=Map3k5 PE=1 SV=3	59729.ENSTGUP00000011202	Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25)(MAPK/ERK kinase kinase 5)(ME [...] 	COG0515	KOG4279	_	PF13281.3|DUF4071|Domain of unknown function (DUF4071)|ENSGALT00000055814|m.12093:182-562;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000055814|m.12093:702-954;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000055814|m.12093:702-949
ENSGALG00000013900	0.158585696	0.428476022	-1.379015816	0.000113013	0.000274811	down	yes	0.184091538	0.112480063	0.179185488	0.430862124	0.420665731	0.433900211	3	55160010	55257947	+	MAP7	protein_coding	GO:0000226|microtubule cytoskeleton organization	GO:0005874|microtubule; GO:0015630|microtubule cytoskeleton; GO:0048471|perinuclear region of cytoplasm	GO:0005198|structural molecule activity	ko:K10433|MAP7	--	3935	XP_015139586.1	XP_015139586.1 ensconsin isoform X4 [Gallus gallus]	sp|Q5ZIA2|MAP7_CHICK	sp|Q5ZIA2|MAP7_CHICK Ensconsin OS=Gallus gallus GN=MAP7 PE=2 SV=1	9031.ENSGALP00000022496	Ensconsin (Microtubule-associated protein 7)(MAP-7); Microtubule-stabilizing protein that ma [...] 	_	_	NOG46082	PF05672.8|MAP7|MAP7 (E-MAP-115) family|ENSGALT00000022537|m.12100:405-568
ENSGALG00000013907	0.538992828	1.472941729	-1.433602702	2.47E-11	1.23E-10	down	yes	0.41692271	0.640489337	0.559566437	1.497302701	1.303427319	1.618095166	4	65185439	65213106	+	KDR	protein_coding	GO:0001525|angiogenesis; GO:0001934|positive regulation of protein phosphorylation; GO:0030154|cell differentiation; GO:0035924|cellular response to vascular endothelial growth factor stimulus; GO:0046777|protein autophosphorylation; GO:0048010|vascular endothelial growth factor receptor signaling pathway	GO:0005769|early endosome; GO:0005783|endoplasmic reticulum; GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0030054|cell junction	GO:0005021|vascular endothelial growth factor-activated receptor activity; GO:0005524|ATP binding; GO:0019838|growth factor binding	"ko:K05098|KDR,VEGFR2,CD309"	ko01521|EGFR tyrosine kinase inhibitor resistance; ko04014|Ras signaling pathway; ko04015|Rap1 signaling pathway; ko04060|Cytokine-cytokine receptor interaction; ko04144|Endocytosis; ko04151|PI3K-Akt signaling pathway; ko04370|VEGF signaling pathway; ko04510|Focal adhesion; ko05205|Proteoglycans in cancer; ko05418|Fluid shear stress and atherosclerosis	5308	NP_001004368.1	NP_001004368.1 vascular endothelial growth factor receptor 2 precursor [Gallus gallus]	sp|P52583|VGFR2_COTJA	sp|P52583|VGFR2_COTJA Vascular endothelial growth factor receptor 2 OS=Coturnix japonica GN=KDR PE=1 SV=1	9031.ENSGALP00000022522	kinase insert domain receptor (a type III receptor tyrosine kinase) 	COG0515	KOG0200	_	PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000022562|m.1093:825-1153;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000022562|m.1093:224-302;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000022562|m.1093:331-393;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000022562|m.1093:542-636;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000022562|m.1093:658-732;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000022562|m.1093:227-303;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000022562|m.1093:329-403;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000022562|m.1093:660-744;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000022562|m.1093:828-926;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000022562|m.1093:990-1152;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000022562|m.1093:664-733;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000022562|m.1093:228-302;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000022562|m.1093:666-735
ENSGALG00000013920	14.34674424	5.657990265	1.340819433	1.21E-46	3.91E-45	up	yes	13.52578028	14.51240653	15.00204592	5.00849366	6.074406467	5.891070668	1	7983063	7992822	+	SUV39H2	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006333|chromatin assembly or disassembly; GO:0006338|chromatin remodeling; GO:0006351|transcription, DNA-templated; GO:0007049|cell cycle; GO:0030154|cell differentiation; GO:0071456|cellular response to hypoxia"	"GO:0000775|chromosome, centromeric region; GO:0000785|chromatin; GO:0005634|nucleus"	GO:0008270|zinc ion binding; GO:0046974|histone methyltransferase activity (H3-K9 specific); GO:1904047|S-adenosyl-L-methionine binding	"ko:K11419|SUV39H,CLR4"	ko00310|Lysine degradation	4254	NP_001026541.1	NP_001026541.1 histone-lysine N-methyltransferase SUV39H2 [Gallus gallus]	sp|Q5F3W5|SUV92_CHICK	sp|Q5F3W5|SUV92_CHICK Histone-lysine N-methyltransferase SUV39H2 OS=Gallus gallus GN=SUV39H2 PE=2 SV=1	9031.ENSGALP00000028525	Histone-lysine N-methyltransferase SUV39H2 (EC 2.1.1.43)(Suppressor of variegation 3-9 homol [...] 	COG2940	KOG1082	_	PF00856.25|SET|SET domain|ENSGALT00000029187|m.348:266-376;PF05033.13|Pre-SET|Pre-SET motif|ENSGALT00000029187|m.348:152-246;PF00385.21|Chromo|Chromo (CHRromatin Organisation MOdifier) domain|ENSGALT00000029187|m.348:51-99
ENSGALG00000013926	2.447887781	6.849530441	-1.480690774	1.84E-31	3.16E-30	down	yes	2.124527224	2.486138773	2.732997347	6.408973425	7.044684265	7.094933633	1	7993092	8003663	-	DCLRE1C	protein_coding	GO:0002250|adaptive immune response; GO:0006303|double-strand break repair via nonhomologous end joining; GO:0006310|DNA recombination; GO:0031848|protection from non-homologous end joining at telomere; GO:0036297|interstrand cross-link repair	"GO:0000784|nuclear chromosome, telomeric region; GO:0070419|nonhomologous end joining complex"	GO:0003684|damaged DNA binding; GO:0004519|endonuclease activity; GO:0035312|5'-3' exodeoxyribonuclease activity	"ko:K10887|DCLRE1C,ARTEMIS,SCIDA"	ko03450|Non-homologous end-joining; ko05340|Primary immunodeficiency	3636	NP_001026765.1	NP_001026765.1 protein artemis [Gallus gallus]	sp|Q5QJC2|DCR1C_CHICK	sp|Q5QJC2|DCR1C_CHICK Protein artemis OS=Gallus gallus GN=DCLRE1C PE=2 SV=1	9031.ENSGALP00000022533	Protein artemis (EC 3.1.-.-)(DNA cross-link repair 1C protein)(chSNM1C)(SNM1-like protein);  [...] 	COG1236	KOG1361	_	PF07522.11|DRMBL|DNA repair metallo-beta-lactamase|ENSGALT00000099032|m.349:170-272
ENSGALG00000013941	2.278199413	5.71384396	-1.322771557	6.91E-17	5.27E-16	down	yes	1.927482916	2.105427486	2.801687836	5.785357344	5.639556378	5.716618158	3	55353526	55514981	-	PDE7B	protein_coding	GO:0006198|cAMP catabolic process; GO:0007165|signal transduction; GO:0007268|chemical synaptic transmission	GO:0005829|cytosol	"GO:0004115|3',5'-cyclic-AMP phosphodiesterase activity; GO:0046872|metal ion binding"	ko:K18436|PDE7	ko00230|Purine metabolism; ko05032|Morphine addiction	2213	XP_015139661.1	"XP_015139661.1 cAMP-specific 3',5'-cyclic phosphodiesterase 7B isoform X1 [Gallus gallus]"	sp|Q9NP56|PDE7B_HUMAN	"sp|Q9NP56|PDE7B_HUMAN cAMP-specific 3',5'-cyclic phosphodiesterase 7B OS=Homo sapiens GN=PDE7B PE=1 SV=1"	9031.ENSGALP00000022555	phosphodiesterase 7B	_	KOG3689	_	PF00233.16|PDEase_I|3'5'-cyclic nucleotide phosphodiesterase|ENSGALT00000108093|m.12136:270-503
ENSGALG00000013971	1.503703847	14.79722535	-3.290146448	8.05E-173	4.05E-170	down	yes	1.786490701	1.347933758	1.376687083	13.86164903	16.45605508	14.07397194	3	56205535	56302921	+	SGK1	protein_coding	GO:0006915|apoptotic process; GO:0006974|cellular response to DNA damage stimulus; GO:0018105|peptidyl-serine phosphorylation; GO:0035556|intracellular signal transduction; GO:0048812|neuron projection morphogenesis	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005783|endoplasmic reticulum; GO:0005829|cytosol; GO:0016607|nuclear speck	GO:0004674|protein serine/threonine kinase activity; GO:0004712|protein serine/threonine/tyrosine kinase activity; GO:0005524|ATP binding	ko:K13302|SGK1	ko04068|FoxO signaling pathway; ko04150|mTOR signaling pathway; ko04151|PI3K-Akt signaling pathway; ko04960|Aldosterone-regulated sodium reabsorption	2831	NP_989807.1	NP_989807.1 serine/threonine-protein kinase Sgk1 [Gallus gallus]	sp|Q6U1I9|SGK1_CHICK	sp|Q6U1I9|SGK1_CHICK Serine/threonine-protein kinase Sgk1 OS=Gallus gallus GN=SGK1 PE=2 SV=1	9031.ENSGALP00000031130	serum/glucocorticoid regulated kinase ; Protein kinase that may play an important role in ce [...] 	COG0515	KOG0598	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000031766|m.12159:114-371;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000031766|m.12159:115-356;PF14531.3|Kinase-like|Kinase-like|ENSGALT00000031766|m.12159:228-355;PF00433.21|Pkinase_C|Protein kinase C terminal domain|ENSGALT00000031766|m.12159:392-439
ENSGALG00000014016	10.11268323	4.964252422	1.025040132	6.66E-25	8.25E-24	up	yes	10.83468161	9.736719648	9.766648445	4.989403389	4.75649588	5.146857998	25	723875	738551	+	MEX3A	protein_coding	--	GO:0000932|P-body; GO:0005634|nucleus; GO:0005829|cytosol	GO:0003723|RNA binding; GO:0046872|metal ion binding	"ko:K15686|MEX3,RKHD"	--	3448	XP_015153825.2	XP_015153825.2 RNA-binding protein MEX3A [Gallus gallus]	sp|A1L020|MEX3A_HUMAN	sp|A1L020|MEX3A_HUMAN RNA-binding protein MEX3A OS=Homo sapiens GN=MEX3A PE=1 SV=1	_	_	_	_	_	"PF00013.26|KH_1|KH domain|ENSGALT00000083041|m.6645:141-201;PF00013.26|KH_1|KH domain|ENSGALT00000083041|m.6645:232-292;PF13920.3|zf-C3HC4_3|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000083041|m.6645:472-518;PF00097.22|zf-C3HC4|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000083041|m.6645:475-514"
ENSGALG00000014124	2.884854573	15.22584796	-2.395907017	1.05E-122	2.60E-120	down	yes	3.000991286	2.814105518	2.839466915	15.17962393	15.57937593	14.91854402	4	66502757	66544534	+	TEC	protein_coding	GO:0002250|adaptive immune response; GO:0006468|protein phosphorylation; GO:0007169|transmembrane receptor protein tyrosine kinase signaling pathway; GO:0007229|integrin-mediated signaling pathway; GO:0010543|regulation of platelet activation; GO:0018108|peptidyl-tyrosine phosphorylation; GO:0030154|cell differentiation; GO:0035556|intracellular signal transduction; GO:0038083|peptidyl-tyrosine autophosphorylation; GO:0038095|Fc-epsilon receptor signaling pathway; GO:0042127|regulation of cell population proliferation; GO:0042246|tissue regeneration; GO:0045087|innate immune response; GO:0050731|positive regulation of peptidyl-tyrosine phosphorylation; GO:0050853|B cell receptor signaling pathway	GO:0005829|cytosol; GO:0005856|cytoskeleton; GO:0005886|plasma membrane; GO:0031234|extrinsic component of cytoplasmic side of plasma membrane	GO:0004715|non-membrane spanning protein tyrosine kinase activity; GO:0005524|ATP binding; GO:0005543|phospholipid binding; GO:0046872|metal ion binding	ko:K07364|TEC	ko04013|MAPK signaling pathway - fly; ko04380|Osteoclast differentiation; ko04660|T cell receptor signaling pathway	3336	XP_015140906.1	XP_015140906.1 tyrosine-protein kinase Tec isoform X1 [Gallus gallus]	sp|P42680|TEC_HUMAN	sp|P42680|TEC_HUMAN Tyrosine-protein kinase Tec OS=Homo sapiens GN=TEC PE=1 SV=2	9031.ENSGALP00000022818	tec protein tyrosine kinase 	COG0515	KOG0197	_	PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000022858|m.1142:371-618;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000022858|m.1142:373-618;PF00017.21|SH2|SH2 domain|ENSGALT00000022858|m.1142:248-331;PF00169.26|PH|PH domain|ENSGALT00000022858|m.1142:8-109;PF00018.25|SH3_1|SH3 domain|ENSGALT00000022858|m.1142:186-232;PF00779.16|BTK|BTK motif|ENSGALT00000022858|m.1142:118-146;PF14604.3|SH3_9|Variant SH3 domain|ENSGALT00000022858|m.1142:187-236;PF07653.14|SH3_2|Variant SH3 domain|ENSGALT00000022858|m.1142:185-235
ENSGALG00000014178	3.673910652	8.935428898	-1.279912584	3.81E-28	5.49E-27	down	yes	3.589552748	3.325028807	4.107150402	8.59574165	8.529614355	9.68093069	1	68564109	68765156	-	ENSGALG00000014178	protein_coding	GO:0030154|cell differentiation; GO:0045880|positive regulation of smoothened signaling pathway; GO:0051260|protein homooligomerization	GO:0005615|extracellular space; GO:0009897|external side of plasma membrane; GO:0009986|cell surface; GO:0019897|extrinsic component of plasma membrane	GO:0005509|calcium ion binding; GO:0042802|identical protein binding; GO:0046982|protein heterodimerization activity	--	--	3546	XP_015146758.1	"XP_015146758.1 signal peptide, CUB and EGF-like domain-containing protein 1 isoform X2 [Gallus gallus]"	sp|Q6NZL8|SCUB1_MOUSE	"sp|Q6NZL8|SCUB1_MOUSE Signal peptide, CUB and EGF-like domain-containing protein 1 OS=Mus musculus GN=Scube1 PE=2 SV=2"	59729.ENSTGUP00000012383	"Signal peptide, CUB and EGF-like domain-containing protein 1 Precursor [Taeniopygia guttata]"	_	KOG1217	_	PF14670.3|FXa_inhibition|Coagulation Factor Xa inhibitory site|ENSGALT00000059111|m.2084:156-191;PF14670.3|FXa_inhibition|Coagulation Factor Xa inhibitory site|ENSGALT00000059111|m.2084:310-345;PF14670.3|FXa_inhibition|Coagulation Factor Xa inhibitory site|ENSGALT00000059111|m.2084:351-386;PF12662.4|cEGF|Complement Clr-like EGF-like|ENSGALT00000059111|m.2084:91-112;PF12662.4|cEGF|Complement Clr-like EGF-like|ENSGALT00000059111|m.2084:133-155;PF12662.4|cEGF|Complement Clr-like EGF-like|ENSGALT00000059111|m.2084:329-350;PF12662.4|cEGF|Complement Clr-like EGF-like|ENSGALT00000059111|m.2084:368-391;PF07699.10|Ephrin_rec_like|Putative ephrin-receptor like|ENSGALT00000059111|m.2084:697-744;PF07699.10|Ephrin_rec_like|Putative ephrin-receptor like|ENSGALT00000059111|m.2084:751-798;PF07699.10|Ephrin_rec_like|Putative ephrin-receptor like|ENSGALT00000059111|m.2084:807-854;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000059111|m.2084:68-107;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000059111|m.2084:109-150;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000059111|m.2084:152-191;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000059111|m.2084:347-386;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000059111|m.2084:388-418;PF07645.12|EGF_CA|Calcium-binding EGF domain|ENSGALT00000059111|m.2084:427-463;PF12947.4|EGF_3|EGF domain|ENSGALT00000059111|m.2084:72-107;PF00431.17|CUB|CUB domain|ENSGALT00000059111|m.2084:859-968;PF00008.24|EGF|EGF-like domain|ENSGALT00000059111|m.2084:72-103
ENSGALG00000014179	1.133727573	0.218434564	2.323890592	4.47E-08	1.66E-07	up	yes	1.15695616	1.211830373	1.032396186	0.161640872	0.235322708	0.258340111	14	13338770	13350329	-	SBK1	protein_coding	GO:0018105|peptidyl-serine phosphorylation; GO:0018107|peptidyl-threonine phosphorylation	GO:0005737|cytoplasm	GO:0004674|protein serine/threonine kinase activity; GO:0005524|ATP binding	ko:K08858|SBK	--	1532	XP_021267621.1	XP_021267621.1 serine/threonine-protein kinase SBK1 isoform X1 [Numida meleagris]	sp|Q52WX2|SBK1_HUMAN	sp|Q52WX2|SBK1_HUMAN Serine/threonine-protein kinase SBK1 OS=Homo sapiens GN=SBK1 PE=2 SV=1	9031.ENSGALP00000022893	SH3-binding domain kinase 1	COG0515	KOG1345	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000103345|m.9922:111-367;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000103345|m.9922:113-366;PF14531.3|Kinase-like|Kinase-like|ENSGALT00000103345|m.9922:221-315
ENSGALG00000014182	0.423614334	1.827817974	-2.083509529	4.05E-08	1.51E-07	down	yes	0.32436375	0.369948107	0.576531145	1.803019476	1.68195466	1.998479787	19	6587381	6595618	+	ADORA2B	protein_coding	GO:0002882|positive regulation of chronic inflammatory response to non-antigenic stimulus; GO:0007189|adenylate cyclase-activating G protein-coupled receptor signaling pathway; GO:0010575|positive regulation of vascular endothelial growth factor production; GO:0031284|positive regulation of guanylate cyclase activity; GO:0031668|cellular response to extracellular stimulus; GO:0032722|positive regulation of chemokine production; GO:0032755|positive regulation of interleukin-6 production; GO:0043306|positive regulation of mast cell degranulation; GO:0060087|relaxation of vascular smooth muscle	GO:0005622|intracellular; GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0001609|G protein-coupled adenosine receptor activity	ko:K04267|ADORA2B	ko04015|Rap1 signaling pathway; ko04020|Calcium signaling pathway; ko04080|Neuroactive ligand-receptor interaction; ko04270|Vascular smooth muscle contraction; ko05034|Alcoholism	1462	POI34001.1	"POI34001.1 hypothetical protein CIB84_002247, partial [Bambusicola thoracicus]"	sp|O13076|AA2BR_CHICK	sp|O13076|AA2BR_CHICK Adenosine receptor A2b OS=Gallus gallus GN=ADORA2B PE=2 SV=1	_	_	_	_	_	PF00001.18|7tm_1|7 transmembrane receptor (rhodopsin family)|ENSGALT00000028044|m.14030:22-290;PF13853.3|7tm_4|Olfactory receptor|ENSGALT00000028044|m.14030:15-306;PF10320.6|7TM_GPCR_Srsx|Serpentine type 7TM GPCR chemoreceptor Srsx|ENSGALT00000028044|m.14030:17-118;PF10328.6|7TM_GPCR_Srx|Serpentine type 7TM GPCR chemoreceptor Srx|ENSGALT00000028044|m.14030:14-135
ENSGALG00000014210	7.31808756	15.85639397	-1.11446563	4.78E-17	3.68E-16	down	yes	7.221621349	8.84444248	5.888198852	15.31244621	16.96749725	15.28923844	4	67593017	67600493	+	GNPDA2	protein_coding	GO:0005975|carbohydrate metabolic process; GO:0006044|N-acetylglucosamine metabolic process	GO:0005634|nucleus; GO:0005737|cytoplasm	GO:0004342|glucosamine-6-phosphate deaminase activity	"ko:K02564|nagB,GNPDA"	ko00520|Amino sugar and nucleotide sugar metabolism; ko01100|Metabolic pathways	1965	XP_005045306.1	XP_005045306.1 PREDICTED: glucosamine-6-phosphate isomerase 2 isoform X4 [Ficedula albicollis]	sp|Q17QL1|GNPI2_BOVIN	sp|Q17QL1|GNPI2_BOVIN Glucosamine-6-phosphate isomerase 2 OS=Bos taurus GN=GNPDA2 PE=2 SV=1	9031.ENSGALP00000022938	glucosamine-6-phosphate deaminase 2	COG0363	KOG3148	_	PF01182.17|Glucosamine_iso|Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase|ENSGALT00000055886|m.1163:9-235
ENSGALG00000014263	6.805548596	15.9202867	-1.22487054	7.99E-49	2.78E-47	down	yes	7.110965565	6.448355558	6.857324666	16.15097475	16.21846007	15.39142529	1	75865514	75884654	+	PHC1	protein_coding	GO:0007275|multicellular organism development; GO:0016574|histone ubiquitination	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0031519|PcG protein complex; GO:0035102|PRC1 complex	GO:0003677|DNA binding; GO:0008270|zinc ion binding	"ko:K11456|PHC1,EDR1"	--	4068	NP_001006249.1	NP_001006249.1 polyhomeotic-like protein 1 [Gallus gallus]	sp|P78364|PHC1_HUMAN	sp|P78364|PHC1_HUMAN Polyhomeotic-like protein 1 OS=Homo sapiens GN=PHC1 PE=1 SV=3	9031.ENSGALP00000023027	polyhomeotic 1-like 	_	KOG3766	_	PF16616.2|PHC2_SAM_assoc|Unstructured region on Polyhomeotic-like protein 1 and 2|ENSGALT00000023070|m.2288:892-999;PF00536.27|SAM_1|SAM domain (Sterile alpha motif)|ENSGALT00000023070|m.2288:1002-1065;PF07647.14|SAM_2|SAM domain (Sterile alpha motif)|ENSGALT00000023070|m.2288:1002-1066
ENSGALG00000014297	4.551905674	18.22760246	-1.999207562	1.62E-69	1.04E-67	down	yes	4.591011269	4.642942689	4.421763064	17.46750003	17.6355208	19.57978656	5	16053125	16056590	+	IRF7	protein_coding	"GO:0002224|toll-like receptor signaling pathway; GO:0006351|transcription, DNA-templated; GO:0051607|defense response to virus"	GO:0005634|nucleus; GO:0005737|cytoplasm	GO:0003700|DNA-binding transcription factor activity; GO:0044212|transcription regulatory region DNA binding	ko:K09447|IRF7	ko04620|Toll-like receptor signaling pathway; ko04621|NOD-like receptor signaling pathway; ko04622|RIG-I-like receptor signaling pathway; ko04623|Cytosolic DNA-sensing pathway; ko05160|Hepatitis C; ko05161|Hepatitis B; ko05162|Measles; ko05164|Influenza A; ko05168|Herpes simplex infection; ko05203|Viral carcinogenesis	1997	AAK58583.1	AAK58583.1 interferon regulatory factor-3 [Gallus gallus]	sp|Q90643|IRF3_CHICK	sp|Q90643|IRF3_CHICK Interferon regulatory factor 3 OS=Gallus gallus GN=IRF3 PE=2 SV=1	9031.ENSGALP00000023072	Interferon regulatory factor 3 (IRF-3); May activate transcription by complex formation with [...] 	_	_	NOG39245	PF10401.6|IRF-3|Interferon-regulatory factor 3|ENSGALT00000039023|m.2649:299-470;PF00605.14|IRF|Interferon regulatory factor transcription factor|ENSGALT00000039023|m.2649:27-127
ENSGALG00000014347	5.515226175	11.28395214	-1.031444995	2.22E-16	1.64E-15	down	yes	5.073212583	6.058297	5.414168943	12.02594102	10.16131231	11.66460309	1	75027120	75040418	-	ENSGALG00000014347	protein_coding	GO:0006998|nuclear envelope organization; GO:0007283|spermatogenesis; GO:0015031|protein transport; GO:0030154|cell differentiation; GO:0051028|mRNA transport	GO:0005635|nuclear envelope; GO:0005643|nuclear pore	GO:0003950|NAD+ ADP-ribosyltransferase activity	ko:K15259|PARP7S	--	2098	XP_416489.2	XP_416489.2 poly [ADP-ribose] polymerase 11 isoform X1 [Gallus gallus]	sp|Q8CFF0|PAR11_MOUSE	sp|Q8CFF0|PAR11_MOUSE Poly [ADP-ribose] polymerase 11 OS=Mus musculus GN=Parp11 PE=2 SV=1	9031.ENSGALP00000023133	"poly (ADP-ribose) polymerase family, member 11"	_	_	NOG81331	PF00644.17|PARP|Poly(ADP-ribose) polymerase catalytic domain|ENSGALT00000074167|m.2235:144-342;PF02825.17|WWE|WWE domain|ENSGALT00000074167|m.2235:40-112
ENSGALG00000014365	15.48735217	36.59559432	-1.240042406	3.13E-05	8.27E-05	down	yes	20.21311731	14.22466127	12.02427791	30.31065548	33.67775267	45.79837482	4	73224322	73315382	-	RBPJ	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0007221|positive regulation of transcription of Notch receptor target; GO:0007275|multicellular organism development; GO:0061419|positive regulation of transcription from RNA polymerase II promoter in response to hypoxia"	GO:0005634|nucleus; GO:0005737|cytoplasm	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0043565|sequence-specific DNA binding"	"ko:K06053|RBPSUH,RBPJK"	ko04330|Notch signaling pathway; ko04658|Th1 and Th2 cell differentiation; ko05169|Epstein-Barr virus infection; ko05203|Viral carcinogenesis	2953	XP_420752.2	XP_420752.2 recombining binding protein suppressor of hairless isoform X4 [Gallus gallus]	sp|Q91880|SUH_XENLA	sp|Q91880|SUH_XENLA Suppressor of hairless protein homolog OS=Xenopus laevis GN=rbpj PE=1 SV=1	9031.ENSGALP00000023161	RBPJk Fragment 	_	KOG3743	_	"PF09270.7|BTD|Beta-trefoil DNA-binding domain|ENSGALT00000100430|m.1256:163-312;PF09271.8|LAG1-DNAbind|LAG1, DNA binding|ENSGALT00000100430|m.1256:32-162;PF01833.21|TIG|IPT/TIG domain|ENSGALT00000100430|m.1256:355-428"
ENSGALG00000014386	8.623190491	18.04502615	-1.064434783	1.77E-36	3.80E-35	down	yes	8.331496995	8.704383079	8.833691399	17.47160234	16.97508686	19.68838924	4	73527042	73550829	+	SEPSECS	protein_coding	GO:0001514|selenocysteine incorporation; GO:0016259|selenocysteine metabolic process; GO:0097056|selenocysteinyl-tRNA(Sec) biosynthetic process	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005829|cytosol	GO:0000049|tRNA binding; GO:0098621|phosphoseryl-selenocysteinyl-tRNA selenium transferase activity	ko:K03341|SEPSECS	ko00450|Selenocompound metabolism; ko00970|Aminoacyl-tRNA biosynthesis	4212	NP_001026329.1	NP_001026329.1 O-phosphoseryl-tRNA(Sec) selenium transferase [Gallus gallus]	sp|Q9HD40|SPCS_HUMAN	sp|Q9HD40|SPCS_HUMAN O-phosphoseryl-tRNA(Sec) selenium transferase OS=Homo sapiens GN=SEPSECS PE=1 SV=2	9031.ENSGALP00000023201	similar to SLA/LP autoantigen 	COG0076	KOG3843	_	"PF05889.10|SepSecS|O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS|ENSGALT00000023246|m.1270:93-491;PF01212.18|Beta_elim_lyase|Beta-eliminating lyase|ENSGALT00000023246|m.1270:230-386"
ENSGALG00000014537	1.376457925	5.609361976	-2.0190025	2.03E-30	3.28E-29	down	yes	1.189278599	1.389256433	1.550838744	5.428796831	5.03041049	6.368878607	5	29608119	29626791	+	BMF	protein_coding	GO:0001844|protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; GO:0010507|negative regulation of autophagy; GO:0032464|positive regulation of protein homooligomerization; GO:0034644|cellular response to UV; GO:0043065|positive regulation of apoptotic process; GO:0043276|anoikis; GO:0090200|positive regulation of release of cytochrome c from mitochondria; GO:1900740|positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; GO:2001244|positive regulation of intrinsic apoptotic signaling pathway	GO:0001669|acrosomal vesicle; GO:0005741|mitochondrial outer membrane; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0016459|myosin complex	--	ko:K17460|BMF	ko05206|MicroRNAs in cancer	2112	OPJ83083.1	OPJ83083.1 bcl-2-modifying factor isoform B [Patagioenas fasciata monilis]	sp|Q96LC9|BMF_HUMAN	sp|Q96LC9|BMF_HUMAN Bcl-2-modifying factor OS=Homo sapiens GN=BMF PE=1 SV=1	9031.ENSGALP00000023408	Bcl-2-modifying factor 	_	_	NOG40671	"PF15185.3|BMF|Bcl-2-modifying factor, apoptosis|ENSGALT00000023454|m.3289:2-193"
ENSGALG00000014624	0.542420164	2.08293016	-1.921686286	4.65E-07	1.54E-06	down	yes	0.792943403	0.290693396	0.543623692	2.490506273	1.928678238	1.829605969	10	17723587	17767097	-	CERS3	protein_coding	GO:0030148|sphingolipid biosynthetic process; GO:0030216|keratinocyte differentiation; GO:0046513|ceramide biosynthetic process	GO:0005783|endoplasmic reticulum; GO:0005789|endoplasmic reticulum membrane; GO:0016021|integral component of membrane; GO:0031965|nuclear membrane	GO:0003677|DNA binding; GO:0050291|sphingosine N-acyltransferase activity	ko:K04710|CERS	ko00600|Sphingolipid metabolism; ko01100|Metabolic pathways; ko04071|Sphingolipid signaling pathway	1329	XP_424275.2	XP_424275.2 ceramide synthase 3 isoform X2 [Gallus gallus]	sp|Q8IU89|CERS3_HUMAN	sp|Q8IU89|CERS3_HUMAN Ceramide synthase 3 OS=Homo sapiens GN=CERS3 PE=1 SV=2	59729.ENSTGUP00000009101	LAG1 longevity assurance homolog 3 [Taeniopygia guttata]	COG5058	KOG1607	_	PF03798.13|TRAM_LAG1_CLN8|TLC domain|ENSGALT00000023574|m.5742:135-329;PF00046.26|Homeobox|Homeobox domain|ENSGALT00000023574|m.5742:86-125
ENSGALG00000014651	3.962527929	1.759719856	1.16653636	3.36E-10	1.52E-09	up	yes	3.765250093	3.615182265	4.507151428	1.922110573	1.905748034	1.451300963	Z	59892416	59896505	+	LYSMD3	protein_coding	--	GO:0016021|integral component of membrane	--	--	--	2351	XP_021235531.1	XP_021235531.1 lysM and putative peptidoglycan-binding domain-containing protein 3 [Numida meleagris]	sp|Q5ZKK0|LYSM3_CHICK	sp|Q5ZKK0|LYSM3_CHICK LysM and putative peptidoglycan-binding domain-containing protein 3 OS=Gallus gallus GN=LYSMD3 PE=2 SV=1	9031.ENSGALP00000023566	LysM and putative peptidoglycan-binding domain-containing protein 3 	_	KOG2850	_	PF01476.17|LysM|LysM domain|ENSGALT00000023612|m.11740:143-177
ENSGALG00000014652	33.4990718	16.63667897	1.009317338	1.08E-40	2.83E-39	up	yes	34.14961995	32.49964152	33.84795392	17.3949848	17.15110787	15.36394424	25	3654868	3663616	-	KIAA0907	protein_coding	GO:0006376|mRNA splice site selection	GO:0005634|nucleus; GO:0005681|spliceosomal complex; GO:0005737|cytoplasm	GO:0003723|RNA binding	--	--	2910	XP_015154102.1	XP_015154102.1 KH homology domain-containing protein 4 isoform X1 [Gallus gallus]	sp|Q5ZL54|BLOM7_CHICK	sp|Q5ZL54|BLOM7_CHICK Protein BLOM7 OS=Gallus gallus GN=BLOM7 PE=2 SV=1	9031.ENSGALP00000023567	UPF0469 protein KIAA0907 homolog 	_	KOG1960	_	_
ENSGALG00000014713	2.38165127	5.332638414	-1.159545336	1.66E-14	1.06E-13	down	yes	2.377982644	2.097490454	2.669480712	5.676210079	4.758987653	5.562717509	Z	16929403	16961191	+	DDX4	protein_coding	GO:0007140|male meiotic nuclear division; GO:0007141|male meiosis I; GO:0007275|multicellular organism development; GO:0007283|spermatogenesis; GO:0010501|RNA secondary structure unwinding; GO:0010529|negative regulation of transposition; GO:0030154|cell differentiation; GO:0030317|flagellated sperm motility; GO:0031047|gene silencing by RNA; GO:0032880|regulation of protein localization; GO:0034587|piRNA metabolic process; GO:0043046|DNA methylation involved in gamete generation; GO:1990511|piRNA biosynthetic process	GO:0005634|nucleus; GO:0005730|nucleolus; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0033391|chromatoid body; GO:0048471|perinuclear region of cytoplasm; GO:0071546|pi-body; GO:0071547|piP-body; GO:1990904|ribonucleoprotein complex	GO:0003676|nucleic acid binding; GO:0003724|RNA helicase activity; GO:0005524|ATP binding; GO:0016887|ATPase activity	"ko:K13982|DDX4,VASA"	--	2947	NP_990039.2	NP_990039.2 probable ATP-dependent RNA helicase DDX4 [Gallus gallus]	sp|Q61496|DDX4_MOUSE	sp|Q61496|DDX4_MOUSE ATP-dependent RNA helicase DDX4 OS=Mus musculus GN=Ddx4 PE=1 SV=2	9031.ENSGALP00000023678	DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 	COG0513	KOG0335	_	PF00270.26|DEAD|DEAD/DEAH box helicase|ENSGALT00000023724|m.10806:281-460;PF00271.28|Helicase_C|Helicase conserved C-terminal domain|ENSGALT00000023724|m.10806:496-604
ENSGALG00000014721	6.896476577	14.10704659	-1.031416501	4.54E-32	8.04E-31	down	yes	6.817443818	6.914911642	6.95707427	12.62746204	15.08105506	14.61262269	Z	17476263	17499010	-	ENSGALG00000014721	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated"	GO:0005634|nucleus	GO:0003677|DNA binding	--	--	5072	XP_004937308.1	XP_004937308.1 mesoderm induction early response protein 3 isoform X1 [Gallus gallus]	sp|Q4R3R9|MIER3_MACFA	sp|Q4R3R9|MIER3_MACFA Mesoderm induction early response protein 3 OS=Macaca fascicularis GN=MIER3 PE=2 SV=1	9031.ENSGALP00000023697	hypothetical LOC425479	_	KOG4329	_	PF01448.21|ELM2|ELM2 domain|ENSGALT00000058578|m.10820:174-220;PF00249.28|Myb_DNA-binding|Myb-like DNA-binding domain|ENSGALT00000058578|m.10820:279-323
ENSGALG00000014727	6.086575502	12.61499366	-1.050211662	1.56E-28	2.28E-27	down	yes	5.299944954	6.874553252	6.0852283	11.97588681	12.73290853	13.13618563	Z	18250991	18507712	-	PDE4D	protein_coding	GO:0002027|regulation of heart rate; GO:0006198|cAMP catabolic process; GO:0006939|smooth muscle contraction; GO:0007568|aging; GO:0010469|regulation of signaling receptor activity; GO:0010880|regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; GO:0019933|cAMP-mediated signaling; GO:0030593|neutrophil chemotaxis; GO:0032729|positive regulation of interferon-gamma production; GO:0032743|positive regulation of interleukin-2 production; GO:0032754|positive regulation of interleukin-5 production; GO:0033137|negative regulation of peptidyl-serine phosphorylation; GO:0035264|multicellular organism growth; GO:0045822|negative regulation of heart contraction; GO:0050852|T cell receptor signaling pathway; GO:0060314|regulation of ryanodine-sensitive calcium-release channel activity; GO:0061028|establishment of endothelial barrier; GO:0071222|cellular response to lipopolysaccharide; GO:0071320|cellular response to cAMP; GO:0071872|cellular response to epinephrine stimulus; GO:0071875|adrenergic receptor signaling pathway; GO:0086004|regulation of cardiac muscle cell contraction; GO:0086024|adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate; GO:1901844|regulation of cell communication by electrical coupling involved in cardiac conduction; GO:1901898|negative regulation of relaxation of cardiac muscle	GO:0005813|centrosome; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0005891|voltage-gated calcium channel complex; GO:0016020|membrane; GO:0016324|apical plasma membrane; GO:0031965|nuclear membrane; GO:0034704|calcium channel complex	"GO:0004114|3',5'-cyclic-nucleotide phosphodiesterase activity; GO:0004115|3',5'-cyclic-AMP phosphodiesterase activity; GO:0008144|drug binding; GO:0019899|enzyme binding; GO:0030552|cAMP binding; GO:0031625|ubiquitin protein ligase binding; GO:0031698|beta-2 adrenergic receptor binding; GO:0044325|ion channel binding; GO:0046872|metal ion binding; GO:0051117|ATPase binding; GO:0097110|scaffold protein binding"	ko:K13293|PDE4	ko00230|Purine metabolism; ko04024|cAMP signaling pathway; ko05032|Morphine addiction	4837	XP_025001021.1	"XP_025001021.1 cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X10 [Gallus gallus]"	sp|Q08499|PDE4D_HUMAN	"sp|Q08499|PDE4D_HUMAN cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Homo sapiens GN=PDE4D PE=1 SV=2"	_	_	_	_	_	PF00233.16|PDEase_I|3'5'-cyclic nucleotide phosphodiesterase|ENSGALT00000091457|m.10830:237-478
ENSGALG00000014751	1.415644332	5.314685308	-1.901082158	7.52E-40	1.86E-38	down	yes	1.277359736	1.543197543	1.426375718	5.312541858	5.13228238	5.499231686	Z	20369274	20519860	-	ADAMTS6	protein_coding	--	GO:0031012|extracellular matrix	GO:0004222|metalloendopeptidase activity; GO:0008237|metallopeptidase activity; GO:0008270|zinc ion binding	ko:K08621|ADAMTS6	--	3630	XP_424749.4	XP_424749.4 A disintegrin and metalloproteinase with thrombospondin motifs 6 [Gallus gallus]	sp|Q9UKP5|ATS6_HUMAN	sp|Q9UKP5|ATS6_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 6 OS=Homo sapiens GN=ADAMTS6 PE=2 SV=2	9031.ENSGALP00000023740	"ADAM metallopeptidase with thrombospondin type 1 motif, 6"	_	KOG3538	_	PF01562.16|Pep_M12B_propep|Reprolysin family propeptide|ENSGALT00000023786|m.10864:43-191;PF05986.11|ADAM_spacer1|ADAM-TS Spacer 1|ENSGALT00000023786|m.10864:720-831;PF01421.16|Reprolysin|Reprolysin (M12B) family zinc metalloprotease|ENSGALT00000023786|m.10864:252-470;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000023786|m.10864:564-614;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000023786|m.10864:850-901;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000023786|m.10864:908-961;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000023786|m.10864:969-1005;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000023786|m.10864:1026-1073;PF13688.3|Reprolysin_5|Metallo-peptidase family M12|ENSGALT00000023786|m.10864:254-445;PF13582.3|Reprolysin_3|Metallo-peptidase family M12B Reprolysin-like|ENSGALT00000023786|m.10864:276-416;PF08686.8|PLAC|PLAC (protease and lacunin) domain|ENSGALT00000023786|m.10864:1085-1117;PF13574.3|Reprolysin_2|Metallo-peptidase family M12B Reprolysin-like|ENSGALT00000023786|m.10864:275-457;PF13583.3|Reprolysin_4|Metallo-peptidase family M12B Reprolysin-like|ENSGALT00000023786|m.10864:255-425
ENSGALG00000014793	2.962981972	6.658598412	-1.165472857	2.17E-21	2.21E-20	down	yes	2.712863929	3.065634962	3.110447024	7.064172053	6.880011052	6.031612131	2	100491423	100845080	+	DLGAP1	protein_coding	GO:0007268|chemical synaptic transmission; GO:0065003|protein-containing complex assembly	GO:0005886|plasma membrane; GO:0014069|postsynaptic density; GO:0030054|cell junction; GO:0045202|synapse; GO:0045211|postsynaptic membrane	GO:0019904|protein domain specific binding	"ko:K15008|DLGAP1,GKAP"	ko04724|Glutamatergic synapse	3392	XP_009700223.1	"XP_009700223.1 PREDICTED: disks large-associated protein 1, partial [Cariama cristata]"	sp|O14490|DLGP1_HUMAN	sp|O14490|DLGP1_HUMAN Disks large-associated protein 1 OS=Homo sapiens GN=DLGAP1 PE=1 SV=1	9031.ENSGALP00000023839	similar to guanylate kinase associated protein	_	KOG3971	_	PF03359.10|GKAP|Guanylate-kinase-associated protein (GKAP) protein|ENSGALT00000055004|m.1559:644-907
ENSGALG00000014799	11.58857958	26.06874252	-1.16892617	6.00E-32	1.05E-30	down	yes	10.12113796	12.76219173	11.88240904	25.3105919	27.30531273	25.59032292	2	101191146	101207940	+	METTL4	protein_coding	--	GO:0005634|nucleus	GO:0003676|nucleic acid binding; GO:0009007|site-specific DNA-methyltransferase (adenine-specific) activity	--	--	1895	XP_419143.3	XP_419143.3 methyltransferase-like protein 4 isoform X1 [Gallus gallus]	sp|Q8N3J2|METL4_HUMAN	sp|Q8N3J2|METL4_HUMAN Methyltransferase-like protein 4 OS=Homo sapiens GN=METTL4 PE=2 SV=3	9031.ENSGALP00000023848	methyltransferase like 4	COG4725	KOG2356	_	PF05063.11|MT-A70|MT-A70|ENSGALT00000060795|m.1593:286-459
ENSGALG00000014807	3.976462906	9.87283878	-1.309816261	1.11E-05	3.10E-05	down	yes	3.664105453	5.533782885	2.731500381	10.03057268	9.710478688	9.877464971	Z	22058070	22068952	+	MTX3	protein_coding	GO:0006626|protein targeting to mitochondrion	GO:0005741|mitochondrial outer membrane	--	ko:K17776|MTX	--	2942	XP_015704108.1	XP_015704108.1 PREDICTED: metaxin-3 isoform X3 [Coturnix japonica]	sp|Q5HYI7|MTX3_HUMAN	sp|Q5HYI7|MTX3_HUMAN Metaxin-3 OS=Homo sapiens GN=MTX3 PE=1 SV=2	9031.ENSGALP00000023859	Putative uncharacterized protein 	_	KOG3028	_	"PF10568.6|Tom37|Outer mitochondrial membrane transport complex protein|ENSGALT00000023906|m.10935:9-144;PF17171.1|GST_C_6|Glutathione S-transferase, C-terminal domain|ENSGALT00000023906|m.10935:175-238;PF17172.1|GST_N_4|Glutathione S-transferase N-terminal domain|ENSGALT00000023906|m.10935:23-119;PF13410.3|GST_C_2|Glutathione S-transferase, C-terminal domain|ENSGALT00000023906|m.10935:171-214"
ENSGALG00000014812	0.469341517	0.153126031	1.55506688	0.002921792	0.005692562	up	yes	0.53417568	0.548321302	0.325527569	0.200929214	0.067604649	0.19084423	1	80053840	80093005	-	SIDT1	protein_coding	GO:0033227|dsRNA transport	GO:0016021|integral component of membrane	GO:0003723|RNA binding; GO:0051033|RNA transmembrane transporter activity	--	--	2466	XP_004938216.2	XP_004938216.2 SID1 transmembrane family member 1 isoform X1 [Gallus gallus]	sp|Q9NXL6|SIDT1_HUMAN	sp|Q9NXL6|SIDT1_HUMAN SID1 transmembrane family member 1 OS=Homo sapiens GN=SIDT1 PE=2 SV=2	9031.ENSGALP00000036191	"SID1 transmembrane family, member 1"	_	_	NOG75860	PF13965.3|SID-1_RNA_chan|dsRNA-gated channel SID-1|ENSGALT00000103566|m.2548:170-821
ENSGALG00000014833	112.230207	45.07634337	1.315827162	3.51E-56	1.53E-54	up	yes	108.1219191	112.8145441	115.7541579	50.95694724	42.41353749	41.85854538	Z	12917710	12920908	-	RPL37	protein_coding	GO:0006412|translation	GO:0022625|cytosolic large ribosomal subunit	GO:0003723|RNA binding; GO:0003735|structural constituent of ribosome; GO:0019843|rRNA binding; GO:0046872|metal ion binding	"ko:K02922|RP-L37e,RPL37"	ko03010|Ribosome	1077	XP_010007048.1	XP_010007048.1 PREDICTED: 60S ribosomal protein L37 [Chaetura pelagica]	sp|P79244|RL37_BOVIN	sp|P79244|RL37_BOVIN 60S ribosomal protein L37 OS=Bos taurus GN=RPL37 PE=3 SV=4	9031.ENSGALP00000023898	ribosomal protein L37	COG2126	KOG3475	_	_
ENSGALG00000014857	10.15233775	32.5766473	-1.681048609	0.000722299	0.00155322	down	yes	4.143496073	13.01310134	13.30041582	35.06362488	32.48556207	30.18075496	Z	13587893	13596605	-	ENSGALG00000014857	protein_coding	GO:0001887|selenium compound metabolic process; GO:0007420|brain development; GO:0007626|locomotory behavior; GO:0009791|post-embryonic development; GO:0010269|response to selenium ion; GO:0019953|sexual reproduction; GO:0040007|growth	GO:0005615|extracellular space; GO:0070062|extracellular exosome	GO:0008430|selenium binding	--	--	2378	NP_001026780.2	NP_001026780.2 selenoprotein P precursor [Gallus gallus]	sp|P25236|SEPP1_RAT	sp|P25236|SEPP1_RAT Selenoprotein P OS=Rattus norvegicus GN=Selenop PE=1 SV=2	9031.ENSGALP00000032221	annotation not avaliable	_	_	NOG78314	_
ENSGALG00000014862	145.4060418	45.02211178	1.691160392	1.59E-74	1.12E-72	up	yes	159.2504359	140.1413378	136.8263518	39.77407753	52.57858025	42.71367757	Z	13647830	13665258	-	HMGCS1	protein_coding	GO:0006695|cholesterol biosynthetic process; GO:0008299|isoprenoid biosynthetic process	GO:0005737|cytoplasm	GO:0004421|hydroxymethylglutaryl-CoA synthase activity	ko:K01641|E2.3.3.10	"ko00072|Synthesis and degradation of ketone bodies; ko00280|Valine, leucine and isoleucine degradation; ko00650|Butanoate metabolism; ko00900|Terpenoid backbone biosynthesis; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko01130|Biosynthesis of antibiotics"	1927	XP_015132738.2	"XP_015132738.2 hydroxymethylglutaryl-CoA synthase, cytoplasmic isoform X1 [Gallus gallus]"	sp|P23228|HMCS1_CHICK	"sp|P23228|HMCS1_CHICK Hydroxymethylglutaryl-CoA synthase, cytoplasmic OS=Gallus gallus GN=HMGCS1 PE=1 SV=1"	9031.ENSGALP00000038170	"Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMG-CoA synthase)(EC 2.3.3.10)(3-hydroxy-3- [...] "	COG3425	KOG1393	_	PF08540.7|HMG_CoA_synt_C|Hydroxymethylglutaryl-coenzyme A synthase C terminal|ENSGALT00000083486|m.10734:214-497;PF01154.14|HMG_CoA_synt_N|Hydroxymethylglutaryl-coenzyme A synthase N terminal|ENSGALT00000083486|m.10734:40-213
ENSGALG00000014876	1.761072346	3.948995892	-1.160511425	4.12E-12	2.18E-11	down	yes	1.807630809	1.523170879	1.952415351	3.282979655	4.668264596	3.895743426	3	61886381	61968901	+	TBC1D32	protein_coding	GO:0002088|lens development in camera-type eye; GO:0003406|retinal pigment epithelium development; GO:0007224|smoothened signaling pathway; GO:0007368|determination of left/right symmetry; GO:0007507|heart development; GO:0021915|neural tube development; GO:0035082|axoneme assembly; GO:0042733|embryonic digit morphogenesis; GO:0043010|camera-type eye development; GO:0060041|retina development in camera-type eye; GO:0060831|smoothened signaling pathway involved in dorsal/ventral neural tube patterning; GO:0061512|protein localization to cilium; GO:1905515|non-motile cilium assembly	GO:0005737|cytoplasm; GO:0005929|cilium	--	--	--	3906	XP_004940317.1	XP_004940317.1 protein broad-minded isoform X1 [Gallus gallus]	sp|Q3URV1|BROMI_MOUSE	sp|Q3URV1|BROMI_MOUSE Protein broad-minded OS=Mus musculus GN=Tbc1d32 PE=1 SV=2	9031.ENSGALP00000023954	annotation not avaliable	_	_	NOG74284	PF14961.3|BROMI|Broad-minded protein|ENSGALT00000024000|m.12274:12-1296
ENSGALG00000014908	0.517365288	1.782621543	-1.765196421	6.76E-10	2.96E-09	down	yes	0.587831623	0.326514134	0.637750107	2.170915854	1.486496652	1.690452122	Z	16072541	16079179	+	FST	protein_coding	GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0002244|hematopoietic progenitor cell differentiation; GO:0010977|negative regulation of neuron projection development; GO:0032926|negative regulation of activin receptor signaling pathway; GO:0046670|positive regulation of retinal cell programmed cell death; GO:0051798|positive regulation of hair follicle development; GO:1901390|positive regulation of transforming growth factor beta activation; GO:1902864|negative regulation of embryonic camera-type eye development; GO:1902867|negative regulation of retina development in camera-type eye; GO:1902870|negative regulation of amacrine cell differentiation; GO:1902873|negative regulation of horizontal cell localization; GO:1902876|negative regulation of embryonic pattern specification	GO:0005615|extracellular space	GO:0048185|activin binding	ko:K04661|FST	ko04350|TGF-beta signaling pathway	2456	XP_015132736.1	XP_015132736.1 follistatin isoform X1 [Gallus gallus]	sp|Q90844|FST_CHICK	sp|Q90844|FST_CHICK Follistatin OS=Gallus gallus GN=FST PE=2 SV=1	59729.ENSTGUP00000002505	Follistatin Precursor (FS)(Activin-binding protein) [Taeniopygia guttata]	_	KOG3649	_	PF07648.12|Kazal_2|Kazal-type serine protease inhibitor domain|ENSGALT00000024043|m.10773:121-163;PF07648.12|Kazal_2|Kazal-type serine protease inhibitor domain|ENSGALT00000024043|m.10773:195-238;PF07648.12|Kazal_2|Kazal-type serine protease inhibitor domain|ENSGALT00000024043|m.10773:273-315;PF00050.18|Kazal_1|Kazal-type serine protease inhibitor domain|ENSGALT00000024043|m.10773:128-163;PF00050.18|Kazal_1|Kazal-type serine protease inhibitor domain|ENSGALT00000024043|m.10773:194-238;PF00050.18|Kazal_1|Kazal-type serine protease inhibitor domain|ENSGALT00000024043|m.10773:270-315;PF09289.7|FOLN|Follistatin/Osteonectin-like EGF domain|ENSGALT00000024043|m.10773:94-115
ENSGALG00000014944	1.020526635	2.574510259	-1.326509135	8.82E-13	4.95E-12	down	yes	1.174174688	0.91471252	0.972692698	2.622378108	2.397371029	2.703781639	Z	24089346	24107538	+	GCNT4	protein_coding	GO:0002121|inter-male aggressive behavior; GO:0005975|carbohydrate metabolic process; GO:0006493|protein O-linked glycosylation; GO:0016266|O-glycan processing; GO:0042403|thyroid hormone metabolic process; GO:0048729|tissue morphogenesis; GO:0048872|homeostasis of number of cells; GO:0060993|kidney morphogenesis	GO:0000139|Golgi membrane; GO:0016021|integral component of membrane	"GO:0003829|beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity; GO:0008109|N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity"	ko:K09663|GCNT4	ko00512|Mucin type O-glycan biosynthesis; ko01100|Metabolic pathways	3590	XP_003643009.1	"XP_003643009.1 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 [Gallus gallus]"	sp|Q9P109|GCNT4_HUMAN	"sp|Q9P109|GCNT4_HUMAN Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 OS=Homo sapiens GN=GCNT4 PE=2 SV=1"	9031.ENSGALP00000024061	"glucosaminyl (N-acetyl) transferase 4, core 2 (beta-1,6-N-acetylglucosaminyltransferase)"	_	KOG0799	_	PF02485.18|Branch|Core-2/I-Branching enzyme|ENSGALT00000024107|m.10999:134-402
ENSGALG00000014954	16.79358592	7.462721805	1.16906342	1.74E-47	5.77E-46	up	yes	16.50662205	17.05105178	16.82308392	7.46295753	7.390174072	7.535033811	4	78250796	78254035	-	ZNF518B	protein_coding	"GO:0006351|transcription, DNA-templated"	GO:0005634|nucleus	"GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0003677|DNA binding; GO:0046872|metal ion binding"	--	--	3240	XP_420787.2	XP_420787.2 zinc finger protein 518B [Gallus gallus]	sp|Q9C0D4|Z518B_HUMAN	sp|Q9C0D4|Z518B_HUMAN Zinc finger protein 518B OS=Homo sapiens GN=ZNF518B PE=1 SV=2	_	_	_	_	_	_
ENSGALG00000014958	0.677917181	0.227039461	1.537107636	0.001017494	0.002141132	up	yes	0.332516582	0.843928084	0.857306878	0.211666247	0.212437765	0.257014371	Z	23843817	23867162	-	ANKDD1B	protein_coding	GO:0007165|signal transduction	--	--	--	--	1980	XP_429150.4	XP_429150.4 ankyrin repeat and death domain-containing protein 1B isoform X1 [Gallus gallus]	sp|A6NHY2|AKD1B_HUMAN	sp|A6NHY2|AKD1B_HUMAN Ankyrin repeat and death domain-containing protein 1B OS=Homo sapiens GN=ANKDD1B PE=4 SV=3	_	_	_	_	_	PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000098780|m.10984:50-140;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000098780|m.10984:185-272;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000098780|m.10984:237-304;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000098780|m.10984:277-338;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000098780|m.10984:315-398;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000098780|m.10984:51-98;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000098780|m.10984:79-130;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000098780|m.10984:112-164;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000098780|m.10984:280-331;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000098780|m.10984:312-364;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000098780|m.10984:97-144;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000098780|m.10984:209-249;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000098780|m.10984:341-384;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000098780|m.10984:211-238;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000098780|m.10984:312-338;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000098780|m.10984:344-371;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000098780|m.10984:212-233;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000098780|m.10984:346-374
ENSGALG00000014966	0.821672855	9.174389168	-3.465095724	1.35E-45	4.20E-44	down	yes	0.558844884	1.024363887	0.881809795	9.699620361	7.751526045	10.0720211	1	80581691	80599590	+	HGD	protein_coding	GO:0006559|L-phenylalanine catabolic process; GO:0006572|tyrosine catabolic process	GO:0005829|cytosol; GO:0070062|extracellular exosome	"GO:0004411|homogentisate 1,2-dioxygenase activity; GO:0042802|identical protein binding; GO:0046872|metal ion binding"	"ko:K00451|HGD,hmgA"	ko00350|Tyrosine metabolism; ko00643|Styrene degradation; ko01100|Metabolic pathways; ko01120|Microbial metabolism in diverse environments	1320	XP_416553.1	"XP_416553.1 homogentisate 1,2-dioxygenase [Gallus gallus]"	sp|Q93099|HGD_HUMAN	"sp|Q93099|HGD_HUMAN Homogentisate 1,2-dioxygenase OS=Homo sapiens GN=HGD PE=1 SV=2"	9031.ENSGALP00000024093	"homogentisate 1,2-dioxygenase"	COG3508	KOG1417	_	"PF04209.10|HgmA|homogentisate 1,2-dioxygenase|ENSGALT00000024139|m.2574:5-434"
ENSGALG00000014973	2.153307097	4.841076816	-1.165066544	3.18E-11	1.57E-10	down	yes	1.963509053	2.293942294	2.202469944	4.73983624	4.130278643	5.653115565	1	80723913	80731661	+	GPR156	protein_coding	--	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0004965|G protein-coupled GABA receptor activity	"ko:K04617|GPR156,GABABL"	ko04080|Neuroactive ligand-receptor interaction	2076	XP_416556.3	XP_416556.3 probable G-protein coupled receptor 156 isoform X3 [Gallus gallus]	sp|Q8NFN8|GP156_HUMAN	sp|Q8NFN8|GP156_HUMAN Probable G-protein coupled receptor 156 OS=Homo sapiens GN=GPR156 PE=2 SV=2	9031.ENSGALP00000024104	G protein-coupled receptor 156	_	KOG1055	_	PF00003.19|7tm_3|7 transmembrane sweet-taste receptor of 3 GCPR|ENSGALT00000024150|m.2579:104-239
ENSGALG00000014975	4.888330121	1.300944627	1.901683259	6.59E-16	4.71E-15	up	yes	5.442815798	4.811454865	4.4107197	1.655268116	1.083940259	1.163625505	4	78488493	78491401	-	DRD5	protein_coding	GO:0007189|adenylate cyclase-activating G protein-coupled receptor signaling pathway	GO:0005622|intracellular; GO:0005887|integral component of plasma membrane	GO:0004952|dopamine neurotransmitter receptor activity	ko:K05840|DRD5	ko04020|Calcium signaling pathway; ko04024|cAMP signaling pathway; ko04080|Neuroactive ligand-receptor interaction; ko04728|Dopaminergic synapse	1278	XP_015141299.1	XP_015141299.1 D(1B) dopamine receptor [Gallus gallus]	sp|P42290|DRD5_XENLA	sp|P42290|DRD5_XENLA D(1B) dopamine receptor OS=Xenopus laevis GN=drd5 PE=2 SV=1	9031.ENSGALP00000036478	dopamine receptor D5	_	KOG3656	_	PF00001.18|7tm_1|7 transmembrane receptor (rhodopsin family)|ENSGALT00000037273|m.1372:29-316;PF10320.6|7TM_GPCR_Srsx|Serpentine type 7TM GPCR chemoreceptor Srsx|ENSGALT00000037273|m.1372:26-328;PF10328.6|7TM_GPCR_Srx|Serpentine type 7TM GPCR chemoreceptor Srx|ENSGALT00000037273|m.1372:27-217
ENSGALG00000014976	7.144114263	42.81175982	-2.581499021	1.06E-98	1.26E-96	down	yes	6.699554285	8.629398279	6.103390224	40.03094094	43.57598806	44.82835045	2	102638198	102654114	+	GATA6	protein_coding	"GO:0030154|cell differentiation; GO:0030513|positive regulation of BMP signaling pathway; GO:0045893|positive regulation of transcription, DNA-templated"	GO:0005634|nucleus; GO:0005667|transcription factor complex	"GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding; GO:0001085|RNA polymerase II transcription factor binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003682|chromatin binding; GO:0008270|zinc ion binding"	ko:K17897|GATA6	--	1164	NP_990751.1	NP_990751.1 transcription factor GATA-6 [Gallus gallus]	sp|P43693|GATA6_CHICK	sp|P43693|GATA6_CHICK Transcription factor GATA-6 OS=Gallus gallus GN=GATA6 PE=2 SV=1	59729.ENSTGUP00000010682	Transcription factor GATA-6 (GATA-binding factor 6) [Taeniopygia guttata]	COG5641	KOG1601	_	"PF05349.9|GATA-N|GATA-type transcription activator, N-terminal|ENSGALT00000031549|m.1617:1-168;PF00320.24|GATA|GATA zinc finger|ENSGALT00000031549|m.1617:181-214;PF00320.24|GATA|GATA zinc finger|ENSGALT00000031549|m.1617:235-268"
ENSGALG00000014978	13.33056181	27.44133191	-1.041056725	6.86E-56	2.95E-54	down	yes	12.91589646	14.18179008	12.89399889	27.11557002	27.2805142	27.92791151	Z	23461532	23577608	-	IQGAP2	protein_coding	GO:0007165|signal transduction; GO:0034314|Arp2/3 complex-mediated actin nucleation; GO:0043312|neutrophil degranulation; GO:0070493|thrombin-activated receptor signaling pathway	GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005874|microtubule; GO:0005886|plasma membrane; GO:0005902|microvillus; GO:0009986|cell surface; GO:0015629|actin cytoskeleton; GO:0030027|lamellipodium; GO:0030175|filopodium; GO:0030667|secretory granule membrane; GO:0070062|extracellular exosome	"GO:0003779|actin binding; GO:0005095|GTPase inhibitor activity; GO:0005516|calmodulin binding; GO:0005547|phosphatidylinositol-3,4,5-trisphosphate binding; GO:0017048|Rho GTPase binding; GO:0048365|Rac GTPase binding; GO:0051015|actin filament binding; GO:0071933|Arp2/3 complex binding"	ko:K05767|IQGAP2_3	ko04810|Regulation of actin cytoskeleton	5472	NP_001264707.1	NP_001264707.1 ras GTPase-activating-like protein IQGAP2 [Gallus gallus]	sp|Q13576|IQGA2_HUMAN	sp|Q13576|IQGA2_HUMAN Ras GTPase-activating-like protein IQGAP2 OS=Homo sapiens GN=IQGAP2 PE=1 SV=4	59729.ENSTGUP00000004223	Ras GTPase-activating-like protein IQGAP2 [Taeniopygia guttata]	COG5261	KOG2128	_	PF00616.16|RasGAP|GTPase-activator protein for Ras-like GTPase|ENSGALT00000081192|m.10976:944-1156;PF03836.12|RasGAP_C|RasGAP C-terminus|ENSGALT00000081192|m.10976:1374-1501;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000081192|m.10976:670-687;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000081192|m.10976:699-716;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000081192|m.10976:728-747;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000081192|m.10976:760-777;PF00307.28|CH|Calponin homology (CH) domain|ENSGALT00000081192|m.10976:54-164
ENSGALG00000014984	1.781368523	0.378143497	2.20640014	2.09E-21	2.13E-20	up	yes	1.966190976	1.52458346	1.853331134	0.393732797	0.419579862	0.321117831	Z	23413354	23422556	-	F2RL1	protein_coding	"GO:0002286|T cell activation involved in immune response; GO:0002690|positive regulation of leukocyte chemotaxis; GO:0002741|positive regulation of cytokine secretion involved in immune response; GO:0003104|positive regulation of glomerular filtration; GO:0006954|inflammatory response; GO:0007186|G protein-coupled receptor signaling pathway; GO:0007204|positive regulation of cytosolic calcium ion concentration; GO:0007596|blood coagulation; GO:0010804|negative regulation of tumor necrosis factor-mediated signaling pathway; GO:0014068|positive regulation of phosphatidylinositol 3-kinase signaling; GO:0030193|regulation of blood coagulation; GO:0030335|positive regulation of cell migration; GO:0030836|positive regulation of actin filament depolymerization; GO:0031274|positive regulation of pseudopodium assembly; GO:0032930|positive regulation of superoxide anion generation; GO:0034137|positive regulation of toll-like receptor 2 signaling pathway; GO:0034140|negative regulation of toll-like receptor 3 signaling pathway; GO:0034141|positive regulation of toll-like receptor 3 signaling pathway; GO:0034145|positive regulation of toll-like receptor 4 signaling pathway; GO:0035025|positive regulation of Rho protein signal transduction; GO:0035926|chemokine (C-C motif) ligand 2 secretion; GO:0042119|neutrophil activation; GO:0043122|regulation of I-kappaB kinase/NF-kappaB signaling; GO:0043123|positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0043311|positive regulation of eosinophil degranulation; GO:0043547|positive regulation of GTPase activity; GO:0045087|innate immune response; GO:0045217|cell-cell junction maintenance; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0046328|regulation of JNK cascade; GO:0046329|negative regulation of JNK cascade; GO:0046330|positive regulation of JNK cascade; GO:0050702|interleukin-1 beta secretion; GO:0050900|leukocyte migration; GO:0050921|positive regulation of chemotaxis; GO:0050927|positive regulation of positive chemotaxis; GO:0051482|positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway; GO:0051607|defense response to virus; GO:0060100|positive regulation of phagocytosis, engulfment; GO:0061028|establishment of endothelial barrier; GO:0070374|positive regulation of ERK1 and ERK2 cascade; GO:0070661|leukocyte proliferation; GO:0070963|positive regulation of neutrophil mediated killing of gram-negative bacterium; GO:0072608|interleukin-10 secretion; GO:0072643|interferon-gamma secretion; GO:0090195|chemokine secretion; GO:0090198|negative regulation of chemokine secretion; GO:0097029|mature conventional dendritic cell differentiation; GO:0097755|positive regulation of blood vessel diameter; GO:1900135|positive regulation of renin secretion into blood stream; GO:2000484|positive regulation of interleukin-8 secretion; GO:2000778|positive regulation of interleukin-6 secretion"	GO:0005769|early endosome; GO:0005794|Golgi apparatus; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0031143|pseudopodium	GO:0001965|G-protein alpha-subunit binding; GO:0004930|G protein-coupled receptor activity; GO:0005102|signaling receptor binding; GO:0015057|thrombin-activated receptor activity; GO:0031681|G-protein beta-subunit binding; GO:0038023|signaling receptor activity	"ko:K04234|F2RL1,PAR2"	ko04080|Neuroactive ligand-receptor interaction; ko04750|Inflammatory mediator regulation of TRP channels; ko05143|African trypanosomiasis	3725	NP_001012626.1	NP_001012626.1 proteinase-activated receptor 2 precursor [Gallus gallus]	sp|P55085|PAR2_HUMAN	sp|P55085|PAR2_HUMAN Proteinase-activated receptor 2 OS=Homo sapiens GN=F2RL1 PE=1 SV=1	9031.ENSGALP00000024125	coagulation factor II (thrombin) receptor-like 1 	_	KOG3656	_	PF00001.18|7tm_1|7 transmembrane receptor (rhodopsin family)|ENSGALT00000024171|m.10972:86-337
ENSGALG00000015013	6.09701682	14.06376515	-1.20446862	2.60E-15	1.78E-14	down	yes	6.021838755	4.996167064	7.273044642	15.46827421	12.86385588	13.85916537	4	78805627	78808134	+	MSX1	protein_coding	GO:0000902|cell morphogenesis; GO:0003198|epithelial to mesenchymal transition involved in endocardial cushion formation; GO:0007517|muscle organ development; GO:0008285|negative regulation of cell population proliferation; GO:0009952|anterior/posterior pattern specification; GO:0010463|mesenchymal cell proliferation; GO:0023019|signal transduction involved in regulation of gene expression; GO:0030308|negative regulation of cell growth; GO:0030513|positive regulation of BMP signaling pathway; GO:0030900|forebrain development; GO:0030901|midbrain development; GO:0034504|protein localization to nucleus; GO:0035115|embryonic forelimb morphogenesis; GO:0035116|embryonic hindlimb morphogenesis; GO:0035880|embryonic nail plate morphogenesis; GO:0042474|middle ear morphogenesis; GO:0042481|regulation of odontogenesis; GO:0043066|negative regulation of apoptotic process; GO:0048863|stem cell differentiation; GO:0050821|protein stabilization; GO:0051154|negative regulation of striated muscle cell differentiation; GO:0060021|roof of mouth development; GO:0060325|face morphogenesis; GO:0060349|bone morphogenesis; GO:0060536|cartilage morphogenesis; GO:0061312|BMP signaling pathway involved in heart development; GO:0090427|activation of meiosis; GO:1902255|positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator; GO:2000678|negative regulation of transcription regulatory region DNA binding; GO:2001055|positive regulation of mesenchymal cell apoptotic process	GO:0005654|nucleoplasm	"GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding; GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0001227|DNA-binding transcription repressor activity, RNA polymerase II-specific; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0002039|p53 binding; GO:0035326|enhancer binding"	ko:K09341|MSX	ko05166|HTLV-I infection	1330	NP_990819.1	NP_990819.1 homeobox protein MSX-1 [Gallus gallus]	sp|P50223|HMGX7_CHICK	sp|P50223|HMGX7_CHICK Homeobox protein GHOX-7 OS=Gallus gallus GN=GHOX-7 PE=2 SV=1	9031.ENSGALP00000024163	Homeobox protein GHOX-7 (CHOX-7)(Hox-7); Probably plays a role in patterning events during e [...] 	_	KOG0492	_	PF00046.26|Homeobox|Homeobox domain|ENSGALT00000024209|m.1383:190-246
ENSGALG00000015028	5.264133547	2.499924043	1.071290397	8.47E-06	2.41E-05	up	yes	5.998200526	4.397885835	5.396314279	2.392363	3.067585842	2.039823287	Z	27624861	27627531	-	RLN3	protein_coding	--	GO:0005576|extracellular region	GO:0001664|G protein-coupled receptor binding; GO:0005179|hormone activity	ko:K05255|RLN	--	1019	NP_001106671.1	NP_001106671.1 relaxin 3 precursor [Gallus gallus]	sp|Q8HY17|REL3_PIG	sp|Q8HY17|REL3_PIG Relaxin-3 OS=Sus scrofa GN=RLN3 PE=1 SV=1	9031.ENSGALP00000024190	Relaxin-like peptide locus B 	_	_	NOG45013	PF00049.15|Insulin|Insulin/IGF/Relaxin family|ENSGALT00000024236|m.11095:75-224
ENSGALG00000015057	4.836527535	13.06889365	-1.432217155	2.07E-30	3.33E-29	down	yes	5.5453122	4.206028677	4.758241728	14.11351432	11.73041528	13.36275137	3	66560138	66566914	+	DDO	protein_coding	GO:0006531|aspartate metabolic process; GO:0006533|aspartate catabolic process; GO:0007320|insemination; GO:0007625|grooming behavior; GO:0019478|D-amino acid catabolic process; GO:0034641|cellular nitrogen compound metabolic process; GO:0042445|hormone metabolic process	GO:0005777|peroxisome; GO:0005782|peroxisomal matrix	GO:0005102|signaling receptor binding; GO:0008445|D-aspartate oxidase activity; GO:0048037|cofactor binding; GO:0071949|FAD binding	ko:K00272|DDO	"ko00250|Alanine, aspartate and glutamate metabolism; ko04146|Peroxisome"	2480	XP_015140058.1	XP_015140058.1 D-aspartate oxidase [Gallus gallus]	sp|Q99489|OXDD_HUMAN	sp|Q99489|OXDD_HUMAN D-aspartate oxidase OS=Homo sapiens GN=DDO PE=2 SV=1	9031.ENSGALP00000024242	D-aspartate oxidase	COG0665	KOG3923	_	PF01266.21|DAO|FAD dependent oxidoreductase|ENSGALT00000024288|m.12381:6-325
ENSGALG00000015070	2.842519066	7.144266965	-1.326567425	6.63E-31	1.09E-29	down	yes	2.617153171	2.898762286	3.011641742	7.299498768	6.937201526	7.196100601	3	66793642	66860116	-	FIG4	protein_coding	GO:0006661|phosphatidylinositol biosynthetic process; GO:0007033|vacuole organization; GO:0007626|locomotory behavior; GO:0010976|positive regulation of neuron projection development; GO:0031642|negative regulation of myelination; GO:0032288|myelin assembly; GO:0043473|pigmentation; GO:0048666|neuron development	GO:0000139|Golgi membrane; GO:0005783|endoplasmic reticulum; GO:0005811|lipid droplet; GO:0010008|endosome membrane; GO:0031901|early endosome membrane; GO:0031902|late endosome membrane; GO:0043231|intracellular membrane-bounded organelle; GO:0055037|recycling endosome	"GO:0004438|phosphatidylinositol-3-phosphatase activity; GO:0043812|phosphatidylinositol-4-phosphate phosphatase activity; GO:0043813|phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity"	--	--	3253	NP_001108095.1	NP_001108095.1 polyphosphoinositide phosphatase precursor [Gallus gallus]	sp|Q92562|FIG4_HUMAN	sp|Q92562|FIG4_HUMAN Polyphosphoinositide phosphatase OS=Homo sapiens GN=FIG4 PE=1 SV=1	9031.ENSGALP00000024266	FIG4 homolog (S. cerevisiae)	COG5329	KOG1888	_	PF02383.15|Syja_N|SacI homology domain|ENSGALT00000024312|m.12390:88-418
ENSGALG00000015096	1.577787477	4.004650434	-1.338256551	1.13E-13	6.80E-13	down	yes	1.835635725	1.483537519	1.414189186	4.29190529	3.910431162	3.811614848	Z	32971787	33062636	+	SH3GL2	protein_coding	GO:0002090|regulation of receptor internalization; GO:0016191|synaptic vesicle uncoating; GO:0097484|dendrite extension; GO:1990416|cellular response to brain-derived neurotrophic factor stimulus	GO:0005769|early endosome; GO:0016020|membrane; GO:0045202|synapse; GO:0070062|extracellular exosome	GO:0008289|lipid binding; GO:0042802|identical protein binding	ko:K11247|SH3GL	ko04144|Endocytosis	2526	NP_989861.1	NP_989861.1 endophilin-A1 [Gallus gallus]	sp|Q8AXV1|SH3G2_CHICK	sp|Q8AXV1|SH3G2_CHICK Endophilin-A1 OS=Gallus gallus GN=SH3GL2 PE=1 SV=1	9031.ENSGALP00000024312	Endophilin-A1 (Endophilin-1)(SH3 domain-containing GRB2-like protein 1)(SH3p4); Implicated i [...] 	_	KOG1118	_	PF03114.15|BAR|BAR domain|ENSGALT00000024358|m.11177:6-241;PF00018.25|SH3_1|SH3 domain|ENSGALT00000024358|m.11177:297-341;PF07653.14|SH3_2|Variant SH3 domain|ENSGALT00000024358|m.11177:296-346;PF14604.3|SH3_9|Variant SH3 domain|ENSGALT00000024358|m.11177:298-346;PF10455.6|BAR_2|Bin/amphiphysin/Rvs domain for vesicular trafficking|ENSGALT00000024358|m.11177:109-240
ENSGALG00000015122	68.79053981	137.8465256	-1.002675772	4.94E-66	2.85E-64	down	yes	68.51667613	66.85305599	71.00188731	137.5546825	132.6418448	143.3430496	2	104150943	104221821	+	TAF4B	protein_coding	GO:0006366|transcription by RNA polymerase II; GO:0006367|transcription initiation from RNA polymerase II promoter; GO:0006368|transcription elongation from RNA polymerase II promoter; GO:0007283|spermatogenesis; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0048477|oogenesis; GO:0051123|RNA polymerase II preinitiation complex assembly; GO:1901796|regulation of signal transduction by p53 class mediator	GO:0001650|fibrillar center; GO:0005654|nucleoplasm; GO:0005669|transcription factor TFIID complex; GO:0005737|cytoplasm	GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity; GO:0003713|transcription coactivator activity; GO:0046982|protein heterodimerization activity; GO:0051059|NF-kappaB binding	ko:K03129|TAF4	ko03022|Basal transcription factors; ko05016|Huntington's disease; ko05168|Herpes simplex infection	2597	XP_025003674.1	XP_025003674.1 transcription initiation factor TFIID subunit 4B isoform X2 [Gallus gallus]	sp|Q92750|TAF4B_HUMAN	sp|Q92750|TAF4B_HUMAN Transcription initiation factor TFIID subunit 4B OS=Homo sapiens GN=TAF4B PE=1 SV=2	9031.ENSGALP00000024358	"TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa"	_	KOG2341	_	PF05236.11|TAF4|Transcription initiation factor TFIID component TAF4 family|ENSGALT00000024404|m.1665:581-829;PF07531.11|TAFH|NHR1 homology to TAF|ENSGALT00000024404|m.1665:236-327
ENSGALG00000015141	0.717671014	2.084856332	-1.525493056	5.28E-07	1.74E-06	down	yes	0.813636336	0.620421223	0.718955484	2.264753969	2.136686908	1.85312812	Z	35688721	35713819	+	GDA	protein_coding	GO:0006147|guanine catabolic process	--	GO:0008270|zinc ion binding; GO:0008892|guanine deaminase activity	"ko:K01487|E3.5.4.3,guaD"	ko00230|Purine metabolism; ko01100|Metabolic pathways	1616	XP_424835.3	XP_424835.3 guanine deaminase [Gallus gallus]	sp|Q5RAV9|GUAD_PONAB	sp|Q5RAV9|GUAD_PONAB Guanine deaminase OS=Pongo abelii GN=GDA PE=2 SV=1	9031.ENSGALP00000024386	guanine deaminase	COG0402	KOG3968	_	PF01979.17|Amidohydro_1|Amidohydrolase family|ENSGALT00000100352|m.11247:93-462;PF07969.8|Amidohydro_3|Amidohydrolase family|ENSGALT00000100352|m.11247:242-463
ENSGALG00000015143	71.10301425	12.92896404	2.458391496	6.12E-143	2.11E-140	up	yes	71.0900156	68.81530253	73.40372462	13.38365473	11.94852472	13.45471268	2	106129430	106138301	+	TTR	protein_coding	GO:0001555|oocyte growth; GO:0009615|response to virus; GO:0042572|retinol metabolic process; GO:0051262|protein tetramerization; GO:0065003|protein-containing complex assembly; GO:0070327|thyroid hormone transport	GO:0005615|extracellular space; GO:0030136|clathrin-coated vesicle; GO:0032991|protein-containing complex; GO:0060417|yolk	GO:0005179|hormone activity; GO:0019904|protein domain specific binding; GO:0036094|small molecule binding; GO:0042562|hormone binding; GO:0046982|protein heterodimerization activity; GO:0070324|thyroid hormone binding	ko:K20731|TTR	ko04918|Thyroid hormone synthesis	736	NP_001268427.1	NP_001268427.1 transthyretin isoform 2 [Gallus gallus]	sp|P27731|TTHY_CHICK	sp|P27731|TTHY_CHICK Transthyretin OS=Gallus gallus GN=TTR PE=1 SV=1	9031.ENSGALP00000024388	Transthyretin Precursor (Prealbumin)(TBPA); Thyroid hormone-binding protein. Probably transp [...] 	_	KOG3006	_	PF00576.18|Transthyretin|HIUase/Transthyretin family|ENSGALT00000024434|m.1687:65-169
ENSGALG00000015145	0.286826294	0.667075195	-1.189697168	0.011961982	0.020847631	down	yes	0.082847624	0.288533763	0.489097495	0.716748628	0.606169754	0.678307204	Z	35819526	35878296	+	TMC1	protein_coding	GO:0006811|ion transport	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	--	--	--	2544	NP_001006580.1	NP_001006580.1 transmembrane channel-like protein 1 [Gallus gallus]	sp|F1QFU0|TMC1_DANRE	sp|F1QFU0|TMC1_DANRE Transmembrane channel-like protein 1 OS=Danio rerio GN=tmc1 PE=1 SV=2	9031.ENSGALP00000024394	transmembrane channel-like 1 	_	_	NOG78939	PF07810.10|TMC|TMC domain|ENSGALT00000024440|m.11253:618-733
ENSGALG00000015152	0.135334525	0.379048769	-1.420573552	0.002500586	0.004935409	down	yes	0.149860891	0.164817203	0.091325482	0.4622332	0.379324381	0.295588727	1	84399987	84443291	-	BOC	protein_coding	GO:0007155|cell adhesion; GO:0007224|smoothened signaling pathway; GO:0007411|axon guidance; GO:0045663|positive regulation of myoblast differentiation; GO:0051149|positive regulation of muscle cell differentiation	GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0044295|axonal growth cone	--	ko:K20020|BOC	ko04340|Hedgehog signaling pathway; ko04360|Axon guidance	3516	XP_024999480.1	XP_024999480.1 brother of CDO isoform X1 [Gallus gallus]	sp|Q9BWV1|BOC_HUMAN	sp|Q9BWV1|BOC_HUMAN Brother of CDO OS=Homo sapiens GN=BOC PE=1 SV=1	9031.ENSGALP00000024403	Boc homolog (mouse)	_	KOG4221	_	PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000024449|m.2668:97-169;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000024449|m.2668:291-363;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000024449|m.2668:382-455;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000024449|m.2668:195-273;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000024449|m.2668:298-370;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000024449|m.2668:383-466;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000024449|m.2668:298-365;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000024449|m.2668:387-459;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000024449|m.2668:545-616;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000024449|m.2668:667-752;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000024449|m.2668:778-861;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000024449|m.2668:196-269;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000024449|m.2668:297-368;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000024449|m.2668:397-464;PF16625.2|ISET-FN3_linker|Unstructured linking region I-set and fnIII on Brother of CDO|ENSGALT00000024449|m.2668:469-532
ENSGALG00000015153	0.456470751	0.15915134	1.463472021	0.001603789	0.003272413	up	yes	0.439238822	0.515280457	0.414892973	0.165218887	0.083384327	0.228850804	2	106222683	106258773	-	OPN5L1	protein_coding	GO:0007601|visual perception; GO:0007602|phototransduction; GO:0018298|protein-chromophore linkage	GO:0016021|integral component of membrane	GO:0004930|G protein-coupled receptor activity; GO:0009881|photoreceptor activity	ko:K08385|OPN5	--	2999	NP_001296985.1	NP_001296985.1 opsin 5-like 1 [Gallus gallus]	sp|Q4U4D2|OPN4_PODSI	sp|Q4U4D2|OPN4_PODSI Melanopsin OS=Podarcis siculus GN=OPN4 PE=2 SV=2	_	_	_	_	_	PF00001.18|7tm_1|7 transmembrane receptor (rhodopsin family)|ENSGALT00000024454|m.1692:141-396
ENSGALG00000015166	0.311072097	0.82951612	-1.386660738	0.000423886	0.000945332	down	yes	0.363108577	0.354975366	0.215132347	0.849847497	1.053126178	0.585574686	Z	37363154	37376174	+	GCNT1	protein_coding	GO:0009101|glycoprotein biosynthetic process; GO:0016266|O-glycan processing; GO:0032868|response to insulin; GO:0048729|tissue morphogenesis; GO:0050901|leukocyte tethering or rolling; GO:0060352|cell adhesion molecule production; GO:0060993|kidney morphogenesis	GO:0000139|Golgi membrane; GO:0005615|extracellular space; GO:0005802|trans-Golgi network; GO:0016021|integral component of membrane; GO:0031985|Golgi cisterna	"GO:0003829|beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity"	ko:K00727|GCNT1	ko00512|Mucin type O-glycan biosynthesis; ko01100|Metabolic pathways	2612	XP_003643070.1	"XP_003643070.1 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase [Gallus gallus]"	sp|Q02742|GCNT1_HUMAN	"sp|Q02742|GCNT1_HUMAN Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase OS=Homo sapiens GN=GCNT1 PE=1 SV=2"	9031.ENSGALP00000024432	"glucosaminyl (N-acetyl) transferase 1, core 2 (beta-1,6-N-acetylglucosaminyltransferase)"	_	KOG0799	_	PF02485.18|Branch|Core-2/I-Branching enzyme|ENSGALT00000024478|m.11280:121-389
ENSGALG00000015182	5.859616238	12.3346517	-1.072548046	1.94E-17	1.54E-16	down	yes	6.043531257	5.566736642	5.968580814	13.47965192	11.56661973	11.95768346	1	84518158	84523562	+	NEPRO	protein_coding	GO:0045665|negative regulation of neuron differentiation; GO:0045747|positive regulation of Notch signaling pathway	GO:0005634|nucleus; GO:0005730|nucleolus	--	--	--	1644	XP_004938279.1	XP_004938279.1 nucleolus and neural progenitor protein isoform X2 [Gallus gallus]	sp|Q6NW34|NEPRO_HUMAN	sp|Q6NW34|NEPRO_HUMAN Nucleolus and neural progenitor protein OS=Homo sapiens GN=NEPRO PE=1 SV=3	9031.ENSGALP00000024454	annotation not avaliable	_	_	NOG48049	PF14780.3|DUF4477|Domain of unknown function (DUF4477)|ENSGALT00000091824|m.2671:53-215
ENSGALG00000015193	0.402403068	0.138836985	1.470321991	0.000131633	0.000317407	up	yes	0.459488052	0.426277886	0.321443267	0.070545142	0.185434536	0.160531278	1	84661651	84685255	+	CCDC80	protein_coding	--	GO:0031012|extracellular matrix	--	--	--	4206	NP_989762.1	NP_989762.1 coiled-coil domain-containing protein 80 precursor [Gallus gallus]	sp|Q8AXP2|CCD80_CHICK	sp|Q8AXP2|CCD80_CHICK Coiled-coil domain-containing protein 80 OS=Gallus gallus GN=CCDC80 PE=2 SV=1	9031.ENSGALP00000024466	Coiled-coil domain-containing protein 80 Precursor (Equarin); Promotes cell adhesion and mat [...] 	_	_	NOG42473	PF13778.3|DUF4174|Domain of unknown function (DUF4174)|ENSGALT00000024512|m.2679:142-270;PF13778.3|DUF4174|Domain of unknown function (DUF4174)|ENSGALT00000024512|m.2679:624-756;PF13778.3|DUF4174|Domain of unknown function (DUF4174)|ENSGALT00000024512|m.2679:779-910
ENSGALG00000015203	1.303462715	0.624962783	1.048631308	0.003633932	0.00697334	up	yes	1.678261852	0.905464507	1.326661785	0.512166635	0.726364016	0.636357698	28	3254654	3257628	+	ENSGALG00000015203	protein_coding	"GO:0002250|adaptive immune response; GO:0006468|protein phosphorylation; GO:0006954|inflammatory response; GO:0007165|signal transduction; GO:0007616|long-term memory; GO:0018105|peptidyl-serine phosphorylation; GO:0033081|regulation of T cell differentiation in thymus; GO:0035556|intracellular signal transduction; GO:0043011|myeloid dendritic cell differentiation; GO:0045670|regulation of osteoclast differentiation; GO:0045893|positive regulation of transcription, DNA-templated; GO:0046777|protein autophosphorylation"	GO:0001650|fibrillar center; GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0070062|extracellular exosome	GO:0004683|calmodulin-dependent protein kinase activity; GO:0005516|calmodulin binding; GO:0005524|ATP binding; GO:0009931|calcium-dependent protein serine/threonine kinase activity	ko:K05869|CAMK4	ko04020|Calcium signaling pathway; ko04024|cAMP signaling pathway; ko04211|Longevity regulating pathway; ko04371|Apelin signaling pathway; ko04380|Osteoclast differentiation; ko04720|Long-term potentiation; ko04722|Neurotrophin signaling pathway; ko04725|Cholinergic synapse; ko04921|Oxytocin signaling pathway; ko04925|Aldosterone synthesis and secretion; ko05031|Amphetamine addiction; ko05034|Alcoholism	1547	XP_015155459.1	XP_015155459.1 calcium/calmodulin-dependent protein kinase type IV isoform X2 [Gallus gallus]	sp|Q16566|KCC4_HUMAN	sp|Q16566|KCC4_HUMAN Calcium/calmodulin-dependent protein kinase type IV OS=Homo sapiens GN=CAMK4 PE=1 SV=1	9031.ENSGALP00000024483	calcium/calmodulin-dependent protein kinase IV	COG0515	KOG0032	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000101830|m.10121:2-181;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000101830|m.10121:15-172
ENSGALG00000015208	1.521832497	5.257146683	-1.781763088	4.73E-27	6.56E-26	down	yes	1.31492914	1.776711817	1.473856533	5.143925422	4.999906101	5.627608526	Z	44480987	44631748	-	ROR2	protein_coding	"GO:0001502|cartilage condensation; GO:0001756|somitogenesis; GO:0007165|signal transduction; GO:0007169|transmembrane receptor protein tyrosine kinase signaling pathway; GO:0007223|Wnt signaling pathway, calcium modulating pathway; GO:0007224|smoothened signaling pathway; GO:0007254|JNK cascade; GO:0007275|multicellular organism development; GO:0008285|negative regulation of cell population proliferation; GO:0014002|astrocyte development; GO:0030282|bone mineralization; GO:0030335|positive regulation of cell migration; GO:0030509|BMP signaling pathway; GO:0030538|embryonic genitalia morphogenesis; GO:0030539|male genitalia development; GO:0042472|inner ear morphogenesis; GO:0042733|embryonic digit morphogenesis; GO:0043507|positive regulation of JUN kinase activity; GO:0045165|cell fate commitment; GO:0045651|positive regulation of macrophage differentiation; GO:0045893|positive regulation of transcription, DNA-templated; GO:0051968|positive regulation of synaptic transmission, glutamatergic; GO:0060071|Wnt signaling pathway, planar cell polarity pathway; GO:0060395|SMAD protein signal transduction; GO:0090090|negative regulation of canonical Wnt signaling pathway; GO:0090263|positive regulation of canonical Wnt signaling pathway; GO:1900020|positive regulation of protein kinase C activity; GO:1905517|macrophage migration"	GO:0005874|microtubule; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0009986|cell surface; GO:0030425|dendrite; GO:0030669|clathrin-coated endocytic vesicle membrane; GO:0043025|neuronal cell body	"GO:0004714|transmembrane receptor protein tyrosine kinase activity; GO:0005109|frizzled binding; GO:0005524|ATP binding; GO:0017147|Wnt-protein binding; GO:0046872|metal ion binding; GO:1904929|coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway"	"ko:K05123|ROR2,NTRKR2"	--	2805	NP_001074185.1	NP_001074185.1 tyrosine-protein kinase transmembrane receptor ROR2 precursor [Gallus gallus]	sp|Q01974|ROR2_HUMAN	sp|Q01974|ROR2_HUMAN Tyrosine-protein kinase transmembrane receptor ROR2 OS=Homo sapiens GN=ROR2 PE=1 SV=2	9031.ENSGALP00000024493	Receptor tyrosine kinase-like orphan receptor 2 	COG0515	KOG1026	_	PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000024539|m.11444:466-738;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000024539|m.11444:467-735;PF00051.15|Kringle|Kringle domain|ENSGALT00000024539|m.11444:308-386;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000024539|m.11444:56-142;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000024539|m.11444:61-131;PF01392.19|Fz|Fz domain|ENSGALT00000024539|m.11444:166-283;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000024539|m.11444:61-132;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000024539|m.11444:62-131
ENSGALG00000015218	1.433410837	0.567437183	1.321746076	0.000385611	0.000865566	up	yes	1.195055629	1.725879656	1.379297226	0.38140922	0.687476558	0.633425771	1	84778681	84788885	+	SLC19A2	protein_coding	GO:0015888|thiamine transport; GO:0042723|thiamine-containing compound metabolic process	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0008517|folic acid transmembrane transporter activity; GO:0015234|thiamine transmembrane transporter activity	"ko:K14610|SLC19A2_3,THTR"	ko04977|Vitamin digestion and absorption	1449	XP_015152175.1	XP_015152175.1 thiamine transporter 1 [Gallus gallus]	sp|O60779|S19A2_HUMAN	sp|O60779|S19A2_HUMAN Thiamine transporter 1 OS=Homo sapiens GN=SLC19A2 PE=1 SV=2	_	_	_	_	_	PF01770.15|Folate_carrier|Reduced folate carrier|ENSGALT00000024560|m.2688:18-446;PF07690.13|MFS_1|Major Facilitator Superfamily|ENSGALT00000024560|m.2688:67-419
ENSGALG00000015283	0.346182893	1.292514367	-1.870609152	1.02E-06	3.25E-06	down	yes	0.356948493	0.221451107	0.46014908	1.445936466	1.205390193	1.226216443	3	67051451	67074362	-	CEP57L1	protein_coding	GO:0008608|attachment of spindle microtubules to kinetochore	GO:0000776|kinetochore; GO:0000777|condensed chromosome kinetochore; GO:0005737|cytoplasm; GO:0005813|centrosome; GO:0005876|spindle microtubule	GO:0008017|microtubule binding; GO:0042802|identical protein binding; GO:0043015|gamma-tubulin binding	ko:K16762|CEP57	--	1887	XP_004940381.1	XP_004940381.1 centrosomal protein CEP57L1 isoform X1 [Gallus gallus]	sp|Q5FWP9|CE57L_XENLA	sp|Q5FWP9|CE57L_XENLA Centrosomal protein cep57l1 OS=Xenopus laevis GN=cep57l1 PE=1 SV=1	9031.ENSGALP00000024620	chromosome 6 open reading frame 182	_	_	NOG19004	PF14073.3|Cep57_CLD|Centrosome localisation domain of Cep57|ENSGALT00000099632|m.12405:49-221;PF06657.10|Cep57_MT_bd|Centrosome microtubule-binding domain of Cep57|ENSGALT00000099632|m.12405:317-387
ENSGALG00000015289	0.924253519	4.611540648	-2.306487874	7.04E-38	1.62E-36	down	yes	1.084250755	0.769329286	0.919180518	4.755928483	4.627076031	4.45161743	3	67151293	67212997	-	ARMC2	protein_coding	--	--	--	--	--	2894	XP_004940390.1	XP_004940390.1 armadillo repeat-containing protein 2 isoform X1 [Gallus gallus]	sp|Q8NEN0|ARMC2_HUMAN	sp|Q8NEN0|ARMC2_HUMAN Armadillo repeat-containing protein 2 OS=Homo sapiens GN=ARMC2 PE=2 SV=4	9031.ENSGALP00000024631	armadillo repeat containing 2	_	KOG1048	_	_
ENSGALG00000015324	1.289729684	0.382863337	1.726112162	2.94E-06	8.85E-06	up	yes	1.009960635	1.650266089	1.208962327	0.455873835	0.273898793	0.418817382	1	86425648	86430040	+	ENSGALG00000015324	protein_coding	--	GO:0016021|integral component of membrane	--	--	--	1758	XP_003640507.1	XP_003640507.1 putative protein FAM172B [Gallus gallus]	sp|A6NC97|F172B_HUMAN	sp|A6NC97|F172B_HUMAN Putative protein FAM172B OS=Homo sapiens GN=FAM172BP PE=5 SV=3	_	_	_	_	_	PF09757.6|Arb2|Arb2 domain|ENSGALT00000106935|m.2756:163-313
ENSGALG00000015328	23.18324065	8.716295917	1.41026311	7.59E-41	2.01E-39	up	yes	24.5059953	24.20729397	20.83643268	8.67636503	9.185920261	8.286602461	1	86432580	86435687	+	TRMT10C	protein_coding	GO:0000964|mitochondrial RNA 5'-end processing; GO:0070131|positive regulation of mitochondrial translation; GO:0070901|mitochondrial tRNA methylation; GO:0090646|mitochondrial tRNA processing	GO:0005654|nucleoplasm; GO:0005739|mitochondrion; GO:0005759|mitochondrial matrix; GO:0030678|mitochondrial ribonuclease P complex; GO:0042645|mitochondrial nucleoid	GO:0003723|RNA binding; GO:0009019|tRNA (guanine-N1-)-methyltransferase activity; GO:0016429|tRNA (adenine-N1-)-methyltransferase activity	"ko:K17654|TRMT10C,MRPP1"	--	1647	XP_015152676.1	XP_015152676.1 tRNA methyltransferase 10 homolog C [Gallus gallus]	sp|Q7L0Y3|MRRP1_HUMAN	sp|Q7L0Y3|MRRP1_HUMAN Mitochondrial ribonuclease P protein 1 OS=Homo sapiens GN=TRMT10C PE=1 SV=2	9031.ENSGALP00000024696	RNA (guanine-9-) methyltransferase domain containing 1	_	KOG2967	_	PF01746.18|tRNA_m1G_MT|tRNA (Guanine-1)-methyltransferase|ENSGALT00000024742|m.2758:202-368
ENSGALG00000015334	17.27772627	35.3729926	-1.033307939	2.32E-35	4.70E-34	down	yes	16.46100323	16.76496413	18.60721144	37.22034161	34.46673304	34.43190315	1	86451332	86456704	-	ZBTB11	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated"	GO:0005654|nucleoplasm	GO:0003677|DNA binding; GO:0046872|metal ion binding	ko:K10498|ZBTB11	--	1991	XP_010718989.1	"XP_010718989.1 PREDICTED: zinc finger and BTB domain-containing protein 11, partial [Meleagris gallopavo]"	sp|O95625|ZBT11_HUMAN	sp|O95625|ZBT11_HUMAN Zinc finger and BTB domain-containing protein 11 OS=Homo sapiens GN=ZBTB11 PE=1 SV=2	9031.ENSGALP00000024702	zinc finger and BTB domain containing 11	COG5048	KOG1721	_	PF13894.3|zf-C2H2_4|C2H2-type zinc finger|ENSGALT00000024748|m.2761:162-184;PF13894.3|zf-C2H2_4|C2H2-type zinc finger|ENSGALT00000024748|m.2761:190-212;PF13894.3|zf-C2H2_4|C2H2-type zinc finger|ENSGALT00000024748|m.2761:221-243;PF13912.3|zf-C2H2_6|C2H2-type zinc finger|ENSGALT00000024748|m.2761:27-50;PF13912.3|zf-C2H2_6|C2H2-type zinc finger|ENSGALT00000024748|m.2761:55-77;PF13912.3|zf-C2H2_6|C2H2-type zinc finger|ENSGALT00000024748|m.2761:106-127;PF13912.3|zf-C2H2_6|C2H2-type zinc finger|ENSGALT00000024748|m.2761:134-157;PF13912.3|zf-C2H2_6|C2H2-type zinc finger|ENSGALT00000024748|m.2761:162-184;PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000024748|m.2761:162-182
ENSGALG00000015338	26.09729387	63.78700338	-1.289035737	3.02E-61	1.55E-59	down	yes	23.87307426	28.78351128	25.63529607	65.02873093	61.78944226	64.54283695	3	68101830	68113781	-	QRSL1	protein_coding	GO:0006412|translation	GO:0005739|mitochondrion; GO:0030956|glutamyl-tRNA(Gln) amidotransferase complex	GO:0004040|amidase activity; GO:0005524|ATP binding; GO:0050567|glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity	"ko:K02433|gatA,QRSL1"	ko00970|Aminoacyl-tRNA biosynthesis; ko01100|Metabolic pathways	1918	XP_419807.2	"XP_419807.2 glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial isoform X1 [Gallus gallus]"	sp|Q29RP9|GATA_BOVIN	"sp|Q29RP9|GATA_BOVIN Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial OS=Bos taurus GN=QRSL1 PE=2 SV=1"	9031.ENSGALP00000024707	glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1	COG0154	KOG1211	_	PF01425.18|Amidase|Amidase|ENSGALT00000024753|m.12435:69-523
ENSGALG00000015346	5.01664182	15.82070899	-1.655059073	2.94E-48	1.01E-46	down	yes	5.378232468	4.434811565	5.236881428	15.25761815	17.99070726	14.21380157	1	86521572	86537922	+	NFKBIZ	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006357|regulation of transcription by RNA polymerase II; GO:0006954|inflammatory response"	GO:0005634|nucleus; GO:0016607|nuclear speck; GO:0036464|cytoplasmic ribonucleoprotein granule	GO:0003712|transcription coregulator activity	ko:K14242|NFKBIZ	ko05202|Transcriptional misregulation in cancer	3380	XP_015151638.1	XP_015151638.1 NF-kappa-B inhibitor zeta isoform X2 [Gallus gallus]	sp|Q9BE45|IKBZ_BOVIN	sp|Q9BE45|IKBZ_BOVIN NF-kappa-B inhibitor zeta OS=Bos taurus GN=NFKBIZ PE=2 SV=2	9031.ENSGALP00000024720	"nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta "	_	KOG0504	_	PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000024766|m.2769:386-466;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000024766|m.2769:489-582;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000024766|m.2769:451-509;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000024766|m.2769:548-583
ENSGALG00000015372	12.50541999	5.720951873	1.126860019	3.29E-06	9.86E-06	up	yes	12.11289405	11.10148054	14.30188537	7.244426609	5.365477962	4.552951049	Z	53568962	53570888	+	ATP5ME	protein_coding	GO:0015986|ATP synthesis coupled proton transport	"GO:0000276|mitochondrial proton-transporting ATP synthase complex, coupling factor F(o); GO:0005739|mitochondrion; GO:0005753|mitochondrial proton-transporting ATP synthase complex"	GO:0015078|proton transmembrane transporter activity; GO:0016887|ATPase activity	"ko:K02129|ATPeF0E,ATP5I"	ko00190|Oxidative phosphorylation; ko01100|Metabolic pathways	435	NP_001091003.1	"NP_001091003.1 ATP synthase subunit e, mitochondrial [Gallus gallus]"	sp|Q06185|ATP5I_MOUSE	"sp|Q06185|ATP5I_MOUSE ATP synthase subunit e, mitochondrial OS=Mus musculus GN=Atp5i PE=1 SV=2"	9031.ENSGALP00000024757	Progesterone receptor binding proteinPutative uncharacterized protein ;	_	_	NOG81326	PF05680.9|ATP-synt_E|ATP synthase E chain|ENSGALT00000024803|m.11589:41-103
ENSGALG00000015375	2.012834366	4.180392957	-1.050707346	0.019825681	0.033000923	down	yes	0.917461777	2.215899483	2.905141839	4.574287677	4.083872458	3.883018736	1	89665094	89684871	+	PLCXD2	protein_coding	GO:0016042|lipid catabolic process	GO:0005634|nucleus	GO:0008081|phosphoric diester hydrolase activity	--	--	2656	XP_010719638.1	"XP_010719638.1 PREDICTED: PI-PLC X domain-containing protein 2, partial [Meleagris gallopavo]"	sp|B2RXA1|PLCX2_MOUSE	sp|B2RXA1|PLCX2_MOUSE PI-PLC X domain-containing protein 2 OS=Mus musculus GN=Plcxd2 PE=2 SV=1	_	_	_	_	_	_
ENSGALG00000015379	0.341202603	0.885162336	-1.349845797	0.007073995	0.012868876	down	yes	0.138660761	0.330415118	0.554531931	0.925786643	0.891147141	0.838553224	1	89826120	89837361	+	TAGLN3	protein_coding	GO:0000122|negative regulation of transcription by RNA polymerase II	GO:0005634|nucleus; GO:0043209|myelin sheath	GO:0051015|actin filament binding	ko:K20526|TAGLN	--	1443	OPJ69452.1	OPJ69452.1 transgelin-3 [Patagioenas fasciata monilis]	sp|Q3ZBY2|TAGL3_BOVIN	sp|Q3ZBY2|TAGL3_BOVIN Transgelin-3 OS=Bos taurus GN=TAGLN3 PE=2 SV=1	_	_	_	_	_	PF00307.28|CH|Calponin homology (CH) domain|ENSGALT00000024814|m.2828:26-134;PF00402.15|Calponin|Calponin family repeat|ENSGALT00000024814|m.2828:174-198
ENSGALG00000015388	3.086529228	21.80210806	-2.816405239	1.03E-120	2.35E-118	down	yes	3.603223818	2.985450591	2.670913276	21.04737032	24.84592141	19.51303244	3	68350477	68445504	-	PRDM1	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0001763|morphogenesis of a branching structure; GO:0001893|maternal placenta development; GO:0002250|adaptive immune response; GO:0003170|heart valve development; GO:0003281|ventricular septum development; GO:0006351|transcription, DNA-templated; GO:0007281|germ cell development; GO:0009791|post-embryonic development; GO:0010628|positive regulation of gene expression; GO:0030889|negative regulation of B cell proliferation; GO:0031665|negative regulation of lipopolysaccharide-mediated signaling pathway; GO:0032823|regulation of natural killer cell differentiation; GO:0033082|regulation of extrathymic T cell differentiation; GO:0035904|aorta development; GO:0042462|eye photoreceptor cell development; GO:0045087|innate immune response; GO:0045165|cell fate commitment; GO:0045579|positive regulation of B cell differentiation; GO:0048844|artery morphogenesis; GO:0051136|regulation of NK T cell differentiation; GO:0060576|intestinal epithelial cell development; GO:0060707|trophoblast giant cell differentiation; GO:0060976|coronary vasculature development; GO:1990654|sebum secreting cell proliferation"	GO:0005654|nucleoplasm; GO:0005737|cytoplasm	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0001227|DNA-binding transcription repressor activity, RNA polymerase II-specific; GO:0003700|DNA-binding transcription factor activity; GO:0008168|methyltransferase activity; GO:0042826|histone deacetylase binding; GO:0046872|metal ion binding; GO:1990841|promoter-specific chromatin binding"	--	--	2886	XP_004940410.1	XP_004940410.1 PR domain zinc finger protein 1 isoform X1 [Gallus gallus]	sp|O75626|PRDM1_HUMAN	sp|O75626|PRDM1_HUMAN PR domain zinc finger protein 1 OS=Homo sapiens GN=PRDM1 PE=1 SV=2	9031.ENSGALP00000024778	Blimp-1 Fragment 	COG5048	KOG2461	_	"PF00096.23|zf-C2H2|Zinc finger, C2H2 type|ENSGALT00000093326|m.12448:539-561;PF13912.3|zf-C2H2_6|C2H2-type zinc finger|ENSGALT00000093326|m.12448:539-563;PF13912.3|zf-C2H2_6|C2H2-type zinc finger|ENSGALT00000093326|m.12448:595-619;PF00856.25|SET|SET domain|ENSGALT00000093326|m.12448:86-164"
ENSGALG00000015433	2.935312237	8.322081132	-1.500256303	2.64E-58	1.23E-56	down	yes	2.688928918	3.047398782	3.069609013	7.769283406	8.678553332	8.518406659	Z	54811100	54902450	-	ABCA1	protein_coding	"GO:0006497|protein lipidation; GO:0006911|phagocytosis, engulfment; GO:0007040|lysosome organization; GO:0007186|G protein-coupled receptor signaling pathway; GO:0007584|response to nutrient; GO:0008203|cholesterol metabolic process; GO:0010745|negative regulation of macrophage derived foam cell differentiation; GO:0010875|positive regulation of cholesterol efflux; GO:0010887|negative regulation of cholesterol storage; GO:0016197|endosomal transport; GO:0019216|regulation of lipid metabolic process; GO:0032367|intracellular cholesterol transport; GO:0032489|regulation of Cdc42 protein signal transduction; GO:0033344|cholesterol efflux; GO:0033700|phospholipid efflux; GO:0034380|high-density lipoprotein particle assembly; GO:0034616|response to laminar fluid shear stress; GO:0042493|response to drug; GO:0042632|cholesterol homeostasis; GO:0043691|reverse cholesterol transport; GO:0045332|phospholipid translocation; GO:0050702|interleukin-1 beta secretion; GO:0055091|phospholipid homeostasis; GO:0060155|platelet dense granule organization; GO:0071222|cellular response to lipopolysaccharide; GO:0071300|cellular response to retinoic acid; GO:0071397|cellular response to cholesterol; GO:0071404|cellular response to low-density lipoprotein particle stimulus; GO:0090107|regulation of high-density lipoprotein particle assembly"	GO:0005789|endoplasmic reticulum membrane; GO:0005794|Golgi apparatus; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0009897|external side of plasma membrane; GO:0030139|endocytic vesicle; GO:0034364|high-density lipoprotein particle; GO:0043231|intracellular membrane-bounded organelle; GO:0045121|membrane raft; GO:0045335|phagocytic vesicle; GO:0048471|perinuclear region of cytoplasm	GO:0005102|signaling receptor binding; GO:0005524|ATP binding; GO:0005543|phospholipid binding; GO:0005548|phospholipid transporter activity; GO:0008509|anion transmembrane transporter activity; GO:0015485|cholesterol binding; GO:0016887|ATPase activity; GO:0019905|syntaxin binding; GO:0031267|small GTPase binding; GO:0034185|apolipoprotein binding; GO:0034186|apolipoprotein A-I binding; GO:0034188|apolipoprotein A-I receptor activity; GO:0042626|ATPase-coupled transmembrane transporter activity; GO:0051117|ATPase binding; GO:0090554|phosphatidylcholine floppase activity; GO:0090556|phosphatidylserine floppase activity; GO:0120020|cholesterol transfer activity	ko:K05641|ABCA1	ko02010|ABC transporters; ko04975|Fat digestion and absorption	7074	NP_989476.1	NP_989476.1 ATP-binding cassette sub-family A member 1 [Gallus gallus]	sp|O95477|ABCA1_HUMAN	sp|O95477|ABCA1_HUMAN ATP-binding cassette sub-family A member 1 OS=Homo sapiens GN=ABCA1 PE=1 SV=3	9031.ENSGALP00000036964	"ATP-binding cassette, sub-family A (ABC1), member 1"	COG1131	KOG0059	_	PF12698.4|ABC2_membrane_3|ABC-2 family transporter protein|ENSGALT00000024891|m.11613:611-842;PF12698.4|ABC2_membrane_3|ABC-2 family transporter protein|ENSGALT00000024891|m.11613:1539-1867;PF00005.24|ABC_tran|ABC transporter|ENSGALT00000024891|m.11613:918-1061;PF00005.24|ABC_tran|ABC transporter|ENSGALT00000024891|m.11613:1929-2071
ENSGALG00000015466	10.04486639	23.49694396	-1.225193081	6.99E-44	2.06E-42	down	yes	10.6986983	9.525215214	9.910685661	23.76490501	24.68507905	22.04084783	3	70959454	70999506	+	SIM1	protein_coding	"GO:0001657|ureteric bud development; GO:0006351|transcription, DNA-templated; GO:0006357|regulation of transcription by RNA polymerase II; GO:0007399|nervous system development; GO:0030154|cell differentiation"	GO:0005634|nucleus	"GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity; GO:0046982|protein heterodimerization activity"	ko:K09100|SIM	--	2758	XP_004940413.1	XP_004940413.1 single-minded homolog 1 isoform X1 [Gallus gallus]	sp|P81133|SIM1_HUMAN	sp|P81133|SIM1_HUMAN Single-minded homolog 1 OS=Homo sapiens GN=SIM1 PE=2 SV=2	9031.ENSGALP00000024893	SIM1 Fragment 	_	KOG3559	_	PF06621.9|SIM_C|Single-minded protein C-terminus|ENSGALT00000024939|m.12480:359-669;PF08447.9|PAS_3|PAS fold|ENSGALT00000024939|m.12480:243-329;PF14598.3|PAS_11|PAS domain|ENSGALT00000024939|m.12480:230-336;PF00989.22|PAS|PAS fold|ENSGALT00000024939|m.12480:81-142;PF00010.23|HLH|Helix-loop-helix DNA-binding domain|ENSGALT00000024939|m.12480:8-51
ENSGALG00000015478	10.95493872	40.62287491	-1.889749695	5.41E-120	1.19E-117	down	yes	9.765270026	12.25245636	10.84708976	39.24210326	43.04744902	39.57907245	3	71429787	71482168	+	USP45	protein_coding	GO:0006281|DNA repair; GO:0006511|ubiquitin-dependent protein catabolic process; GO:0016579|protein deubiquitination; GO:0070911|global genome nucleotide-excision repair	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm	GO:0004843|thiol-dependent ubiquitin-specific protease activity; GO:0008270|zinc ion binding	ko:K11844|USP16_45	--	4563	XP_025004511.1	XP_025004511.1 ubiquitin carboxyl-terminal hydrolase 45 isoform X1 [Gallus gallus]	sp|Q70EL2|UBP45_HUMAN	sp|Q70EL2|UBP45_HUMAN Ubiquitin carboxyl-terminal hydrolase 45 OS=Homo sapiens GN=USP45 PE=1 SV=3	9031.ENSGALP00000024915	hypothetical protein LOC421793 	COG5560	KOG1873	_	PF00443.26|UCH|Ubiquitin carboxyl-terminal hydrolase|ENSGALT00000024962|m.12486:261-449;PF13423.3|UCH_1|Ubiquitin carboxyl-terminal hydrolase|ENSGALT00000024962|m.12486:157-398;PF02148.16|zf-UBP|Zn-finger in ubiquitin-hydrolases and other protein|ENSGALT00000024962|m.12487:66-141;PF00443.26|UCH|Ubiquitin carboxyl-terminal hydrolase|ENSGALT00000024962|m.12488:34-113
ENSGALG00000015483	16.37732319	5.973379614	1.453547712	1.05E-57	4.76E-56	up	yes	16.15966836	17.33207684	15.64022437	5.759146737	6.397423856	5.763568251	3	71486522	71511444	+	PNISR	protein_coding	--	GO:0005829|cytosol; GO:0016607|nuclear speck	GO:0003723|RNA binding	ko:K13170|SFRS18	--	3169	NP_001026251.2	NP_001026251.2 arginine/serine-rich protein PNISR [Gallus gallus]	sp|A2AJT4|PNISR_MOUSE	sp|A2AJT4|PNISR_MOUSE Arginine/serine-rich protein PNISR OS=Mus musculus GN=Pnisr PE=1 SV=1	9031.ENSGALP00000024924	hypothetical protein LOC421796 	_	_	NOG129831	PF15996.2|PNISR|Arginine/serine-rich protein PNISR|ENSGALT00000024970|m.12490:224-392
ENSGALG00000015556	16.36788452	39.16605984	-1.258223284	2.61E-70	1.72E-68	down	yes	14.94117184	17.32670419	16.83577752	38.91168962	39.40023504	39.18625486	4	80530710	80589183	-	AFAP1	protein_coding	GO:0009966|regulation of signal transduction; GO:0018108|peptidyl-tyrosine phosphorylation; GO:0018109|peptidyl-arginine phosphorylation; GO:0051493|regulation of cytoskeleton organization	GO:0005737|cytoplasm; GO:0005856|cytoskeleton; GO:0005886|plasma membrane	GO:0003779|actin binding; GO:0017124|SH3 domain binding; GO:0042169|SH2 domain binding	ko:K18616|AFAP1	--	2945	NP_989536.1	NP_989536.1 actin filament-associated protein 1 isoform a [Gallus gallus]	sp|Q90738|AFAP1_CHICK	sp|Q90738|AFAP1_CHICK Actin filament-associated protein 1 OS=Gallus gallus GN=AFAP1 PE=1 SV=2	_	_	_	_	_	PF00169.26|PH|PH domain|ENSGALT00000025080|m.1425:161-249;PF00169.26|PH|PH domain|ENSGALT00000025080|m.1425:359-437
ENSGALG00000015590	11.64833551	4.197529259	1.470316616	7.99E-16	5.66E-15	up	yes	12.1594821	12.0417251	10.74379932	4.935085955	5.059211517	2.598290305	3	73174355	73186779	-	MANEA	protein_coding	--	GO:0000139|Golgi membrane; GO:0016021|integral component of membrane	"GO:0004569|glycoprotein endo-alpha-1,2-mannosidase activity"	ko:K15538|MANEA	--	2185	XP_419831.2	"XP_419831.2 glycoprotein endo-alpha-1,2-mannosidase [Gallus gallus]"	sp|Q6DE40|MANEA_XENLA	"sp|Q6DE40|MANEA_XENLA Glycoprotein endo-alpha-1,2-mannosidase OS=Xenopus laevis GN=manea PE=2 SV=1"	9031.ENSGALP00000031047	"mannosidase, endo-alpha"	_	_	NOG84309	PF16317.2|Glyco_hydro_99|Glycosyl hydrolase family 99|ENSGALT00000094113|m.12521:102-450
ENSGALG00000015591	0.853907621	4.742049415	-2.459600882	6.96E-31	1.14E-29	down	yes	0.518613082	0.963293824	1.079815958	3.966532546	4.984162752	5.275452948	4	80933353	80968494	-	ACOX3	protein_coding	GO:0033539|fatty acid beta-oxidation using acyl-CoA dehydrogenase; GO:0033540|fatty acid beta-oxidation using acyl-CoA oxidase	GO:0005739|mitochondrion; GO:0005777|peroxisome; GO:0005782|peroxisomal matrix; GO:0016020|membrane	GO:0003995|acyl-CoA dehydrogenase activity; GO:0005102|signaling receptor binding; GO:0016402|pristanoyl-CoA oxidase activity; GO:0050660|flavin adenine dinucleotide binding; GO:0071949|FAD binding	"ko:K00232|E1.3.3.6,ACOX1,ACOX3"	ko00071|Fatty acid degradation; ko00592|alpha-Linolenic acid metabolism; ko01040|Biosynthesis of unsaturated fatty acids; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko01212|Fatty acid metabolism; ko03320|PPAR signaling pathway; ko04024|cAMP signaling pathway; ko04146|Peroxisome	3048	XP_420814.4	XP_420814.4 peroxisomal acyl-coenzyme A oxidase 3 isoform X1 [Gallus gallus]	sp|O15254|ACOX3_HUMAN	sp|O15254|ACOX3_HUMAN Peroxisomal acyl-coenzyme A oxidase 3 OS=Homo sapiens GN=ACOX3 PE=1 SV=2	9031.ENSGALP00000025093	"acyl-Coenzyme A oxidase 3, pristanoyl"	COG1960	KOG0135	_	"PF01756.16|ACOX|Acyl-CoA oxidase|ENSGALT00000025139|m.1446:518-692;PF02770.16|Acyl-CoA_dh_M|Acyl-CoA dehydrogenase, middle domain|ENSGALT00000025139|m.1446:162-273;PF14749.3|Acyl-CoA_ox_N|Acyl-coenzyme A oxidase N-terminal|ENSGALT00000025139|m.1446:39-160;PF00441.21|Acyl-CoA_dh_1|Acyl-CoA dehydrogenase, C-terminal domain|ENSGALT00000025139|m.1446:305-467"
ENSGALG00000015598	0.956708401	3.865628344	-2.003277545	4.25E-29	6.34E-28	down	yes	0.883170458	0.804204576	1.182750168	3.520279835	4.090081284	3.986523912	Z	63986799	64109277	-	RASGRF2	protein_coding	GO:0000165|MAPK cascade; GO:0007264|small GTPase mediated signal transduction; GO:0034976|response to endoplasmic reticulum stress; GO:0035023|regulation of Rho protein signal transduction; GO:0043065|positive regulation of apoptotic process; GO:0051056|regulation of small GTPase mediated signal transduction	GO:0005783|endoplasmic reticulum; GO:0005789|endoplasmic reticulum membrane; GO:0005829|cytosol; GO:0005886|plasma membrane	GO:0005085|guanyl-nucleotide exchange factor activity; GO:0005088|Ras guanyl-nucleotide exchange factor activity; GO:0005089|Rho guanyl-nucleotide exchange factor activity; GO:0005516|calmodulin binding	ko:K12326|RASGRF2	ko04010|MAPK signaling pathway; ko04014|Ras signaling pathway	3699	XP_003643125.1	XP_003643125.1 ras-specific guanine nucleotide-releasing factor 2 isoform X4 [Gallus gallus]	sp|O14827|RGRF2_HUMAN	sp|O14827|RGRF2_HUMAN Ras-specific guanine nucleotide-releasing factor 2 OS=Homo sapiens GN=RASGRF2 PE=1 SV=2	13616.ENSMODP00000025346	Ras protein-specific guanine nucleotide-releasing factor 2	_	KOG3417	_	PF00617.16|RasGEF|RasGEF domain|ENSGALT00000025150|m.11778:1000-1178;PF00621.17|RhoGEF|RhoGEF domain|ENSGALT00000025150|m.11778:241-417;PF00618.17|RasGEF_N|RasGEF N-terminal motif|ENSGALT00000025150|m.11778:631-743;PF00169.26|PH|PH domain|ENSGALT00000025150|m.11778:25-125
ENSGALG00000015605	4.352281958	8.735255844	-1.003417569	5.06E-20	4.76E-19	down	yes	4.219211977	4.340534181	4.497099716	9.331601718	8.414559973	8.45960584	3	75307454	75404609	+	BACH2	protein_coding	GO:0006366|transcription by RNA polymerase II; GO:0016567|protein ubiquitination; GO:0051170|import into nucleus	GO:0005634|nucleus; GO:0005829|cytosol; GO:0031463|Cul3-RING ubiquitin ligase complex	"GO:0000980|RNA polymerase II distal enhancer sequence-specific DNA binding; GO:0001227|DNA-binding transcription repressor activity, RNA polymerase II-specific; GO:0003700|DNA-binding transcription factor activity"	ko:K09042|BACH	--	2963	XP_021245273.1	XP_021245273.1 transcription regulator protein BACH2 isoform X1 [Numida meleagris]	sp|Q9BYV9|BACH2_HUMAN	sp|Q9BYV9|BACH2_HUMAN Transcription regulator protein BACH2 OS=Homo sapiens GN=BACH2 PE=1 SV=1	_	_	_	_	_	PF00651.28|BTB|BTB/POZ domain|ENSGALT00000101093|m.12532:53-158;PF03131.14|bZIP_Maf|bZIP Maf transcription factor|ENSGALT00000101093|m.12532:628-711;PF00170.18|bZIP_1|bZIP transcription factor|ENSGALT00000101093|m.12532:661-714;PF07716.12|bZIP_2|Basic region leucine zipper|ENSGALT00000101093|m.12532:660-706
ENSGALG00000015624	0.092012052	0.277215567	-1.493394341	0.000380507	0.00085554	down	yes	0.02570297	0.191595308	0.058737877	0.299711897	0.260912724	0.27102208	Z	62855240	62961099	-	VCAN	protein_coding	GO:0001501|skeletal system development; GO:0007155|cell adhesion; GO:0007417|central nervous system development	GO:0031012|extracellular matrix	GO:0005201|extracellular matrix structural constituent; GO:0005509|calcium ion binding; GO:0005540|hyaluronic acid binding; GO:0030246|carbohydrate binding	"ko:K06793|VCAN,CSPG2"	ko04514|Cell adhesion molecules (CAMs)	12300	XP_015136070.1	XP_015136070.1 versican core protein isoform X1 [Gallus gallus]	sp|Q90953|CSPG2_CHICK	sp|Q90953|CSPG2_CHICK Versican core protein OS=Gallus gallus GN=VCAN PE=2 SV=1	9031.ENSGALP00000025144	versican; May play a role in intercellular signaling and in connecting cells with the extrac [...] 	_	KOG1218	_	PF00193.14|Xlink|Extracellular link domain|ENSGALT00000025190|m.11764:150-243;PF00193.14|Xlink|Extracellular link domain|ENSGALT00000025190|m.11764:251-345;PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000025190|m.11764:3349-3453;PF07686.14|V-set|Immunoglobulin V-set domain|ENSGALT00000025190|m.11764:30-146;PF00008.24|EGF|EGF-like domain|ENSGALT00000025190|m.11764:3255-3284;PF00008.24|EGF|EGF-like domain|ENSGALT00000025190|m.11764:3293-3322;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000025190|m.11764:3458-3514
ENSGALG00000015628	1.050032643	2.165469457	-1.03721807	0.000204462	0.000478503	down	yes	1.196789624	1.090930022	0.862378284	1.99534921	2.430592572	2.070466589	4	82077210	82093294	-	MSANTD1	protein_coding	--	--	--	--	--	1629	XP_015141341.1	XP_015141341.1 myb/SANT-like DNA-binding domain-containing protein 1 isoform X1 [Gallus gallus]	sp|Q6ZTZ1|MSD1_HUMAN	sp|Q6ZTZ1|MSD1_HUMAN Myb/SANT-like DNA-binding domain-containing protein 1 OS=Homo sapiens GN=MSANTD1 PE=2 SV=2	_	_	_	_	_	PF13837.3|Myb_DNA-bind_4|Myb/SANT-like DNA-binding domain|ENSGALT00000037207|m.1466:42-129
ENSGALG00000015665	1.05223383	3.020705792	-1.512552425	9.81E-17	7.39E-16	down	yes	1.099062251	0.908905111	1.148734129	2.677552593	3.57848806	2.806076722	4	82359242	82394778	-	SH3BP2	protein_coding	GO:0007165|signal transduction	--	GO:0001784|phosphotyrosine residue binding; GO:0005070|SH3/SH2 adaptor activity; GO:0017124|SH3 domain binding	ko:K07984|SH3BP2	ko04650|Natural killer cell mediated cytotoxicity	3905	XP_015141269.1	XP_015141269.1 SH3 domain-binding protein 2 isoform X5 [Gallus gallus]	sp|P78314|3BP2_HUMAN	sp|P78314|3BP2_HUMAN SH3 domain-binding protein 2 OS=Homo sapiens GN=SH3BP2 PE=1 SV=2	9031.ENSGALP00000025216	SH3-domain binding protein 2 	_	_	NOG42035	PF00169.26|PH|PH domain|ENSGALT00000025262|m.1479:46-148;PF00017.21|SH2|SH2 domain|ENSGALT00000025262|m.1479:476-535
ENSGALG00000015666	2.717500017	13.62806366	-2.321987713	7.70E-64	4.27E-62	down	yes	2.685327453	2.183972635	3.283199962	13.79312367	14.07422398	13.01684332	4	82441244	82449180	+	TNIP2	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006915|apoptotic process; GO:0006954|inflammatory response; GO:0007249|I-kappaB kinase/NF-kappaB signaling; GO:0016579|protein deubiquitination; GO:0023035|CD40 signaling pathway; GO:0034134|toll-like receptor 2 signaling pathway; GO:0034138|toll-like receptor 3 signaling pathway; GO:0034162|toll-like receptor 9 signaling pathway; GO:0043032|positive regulation of macrophage activation; GO:0043123|positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0050821|protein stabilization; GO:0050871|positive regulation of B cell activation; GO:0051403|stress-activated MAPK cascade; GO:0070498|interleukin-1-mediated signaling pathway; GO:0071222|cellular response to lipopolysaccharide; GO:2000352|negative regulation of endothelial cell apoptotic process"	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005829|cytosol	GO:0019901|protein kinase binding; GO:0031593|polyubiquitin modification-dependent protein binding; GO:0046872|metal ion binding; GO:0070530|K63-linked polyubiquitin modification-dependent protein binding	--	--	2335	NP_001026337.2	NP_001026337.2 TNFAIP3-interacting protein 2 [Gallus gallus]	sp|Q8NFZ5|TNIP2_HUMAN	sp|Q8NFZ5|TNIP2_HUMAN TNFAIP3-interacting protein 2 OS=Homo sapiens GN=TNIP2 PE=1 SV=1	_	_	_	_	_	PF12180.5|EABR|TSG101 and ALIX binding domain of CEP55|ENSGALT00000080638|m.1480:295-328
ENSGALG00000015685	0.282211879	0.643895553	-1.162045385	0.016948242	0.028541548	down	yes	0.150915558	0.268724873	0.426995205	0.600104202	0.946458175	0.385124281	4	82596511	82644224	-	CFAP99	protein_coding	--	GO:0042995|cell projection	--	--	--	2444	XP_004936279.1	XP_004936279.1 cilia- and flagella-associated protein 99 isoform X1 [Gallus gallus]	sp|D6REC4|CFA99_HUMAN	sp|D6REC4|CFA99_HUMAN Cilia- and flagella-associated protein 99 OS=Homo sapiens GN=CFAP99 PE=3 SV=1	9031.ENSGALP00000025252	hypothetical gene supported by CR390999	_	_	NOG70709	_
ENSGALG00000015699	14.87843454	31.99665567	-1.104179871	1.47E-60	7.38E-59	down	yes	14.31823073	15.36281541	14.95425749	29.96480356	33.33215863	32.69300482	4	83173167	83196460	+	NELFA	protein_coding	"GO:0006355|regulation of transcription, DNA-templated; GO:0006366|transcription by RNA polymerase II; GO:0006368|transcription elongation from RNA polymerase II promoter; GO:0007275|multicellular organism development; GO:0050434|positive regulation of viral transcription"	GO:0005654|nucleoplasm; GO:0005829|cytosol; GO:0016604|nuclear body; GO:0032021|NELF complex	--	"ko:K15179|WHSC2,NELFA"	--	5980	XP_025005481.1	XP_025005481.1 negative elongation factor A isoform X1 [Gallus gallus]	sp|Q9H3P2|NELFA_HUMAN	sp|Q9H3P2|NELFA_HUMAN Negative elongation factor A OS=Homo sapiens GN=NELFA PE=1 SV=3	9031.ENSGALP00000025273	Wolf-Hirschhorn syndrome candidate 2 	_	_	NOG71944	_
ENSGALG00000015712	11.44170188	23.71651117	-1.050937959	1.86E-27	2.63E-26	down	yes	12.56771411	10.54020148	11.21719003	23.76823367	23.94136161	23.43993823	4	83930355	83937106	+	SLBP	protein_coding	GO:0006398|mRNA 3'-end processing by stem-loop binding and cleavage; GO:0033260|nuclear DNA replication; GO:0044770|cell cycle phase transition; GO:0051028|mRNA transport	GO:0005634|nucleus; GO:0005730|nucleolus; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0071204|histone pre-mRNA 3'end processing complex; GO:1990904|ribonucleoprotein complex	GO:0003723|RNA binding; GO:0003729|mRNA binding; GO:0071207|histone pre-mRNA stem-loop binding	ko:K18710|SLBP	--	1807	NP_001004403.1	NP_001004403.1 histone RNA hairpin-binding protein [Gallus gallus]	sp|P97440|SLBP_MOUSE	sp|P97440|SLBP_MOUSE Histone RNA hairpin-binding protein OS=Mus musculus GN=Slbp PE=1 SV=1	9031.ENSGALP00000025292	stem-loop (histone) binding protein 	_	KOG3934	_	PF15247.3|SLBP_RNA_bind|Histone RNA hairpin-binding protein RNA-binding domain|ENSGALT00000025338|m.1513:158-226
ENSGALG00000015768	0.908652466	2.269016957	-1.310820573	1.66E-09	7.04E-09	down	yes	0.825403889	0.951007905	0.949545603	2.40142272	2.524946121	1.880682028	3	75547294	75651254	-	ANKRD6	protein_coding	"GO:0046330|positive regulation of JNK cascade; GO:0090090|negative regulation of canonical Wnt signaling pathway; GO:2000096|positive regulation of Wnt signaling pathway, planar cell polarity pathway"	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0043231|intracellular membrane-bounded organelle	--	ko:K21435|--	--	3128	XP_015140180.1	XP_015140180.1 ankyrin repeat domain-containing protein 6 isoform X3 [Gallus gallus]	sp|Q9Y2G4|ANKR6_HUMAN	sp|Q9Y2G4|ANKR6_HUMAN Ankyrin repeat domain-containing protein 6 OS=Homo sapiens GN=ANKRD6 PE=2 SV=3	9031.ENSGALP00000025385	ankyrin repeat domain 6	COG0666	KOG0504	_	PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000107298|m.12545:14-105;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000107298|m.12545:65-137;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000107298|m.12545:140-203;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000107298|m.12545:205-265;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000107298|m.12545:14-62;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000107298|m.12545:42-83;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000107298|m.12545:77-128;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000107298|m.12545:123-161;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000107298|m.12545:175-227;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000107298|m.12545:208-259;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000107298|m.12545:37-82;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000107298|m.12545:94-148;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000107298|m.12545:194-247;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000107298|m.12545:41-73;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000107298|m.12545:76-105;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000107298|m.12545:107-139;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000107298|m.12545:141-169;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000107298|m.12545:174-195;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000107298|m.12545:207-238;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000107298|m.12545:41-70;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000107298|m.12545:174-199;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000107298|m.12545:207-232
ENSGALG00000015795	0.236278986	0.593873847	-1.29395366	0.003760419	0.007197394	down	yes	0.32006736	0.190672354	0.198097244	0.511669219	0.830717153	0.439235168	1	104379620	104419315	-	ADAMTS5	protein_coding	GO:0006508|proteolysis; GO:0022617|extracellular matrix disassembly; GO:0036066|protein O-linked fucosylation; GO:0042742|defense response to bacterium; GO:0044691|tooth eruption	GO:0005576|extracellular region; GO:0005615|extracellular space; GO:0005788|endoplasmic reticulum lumen; GO:0031012|extracellular matrix	GO:0004222|metalloendopeptidase activity; GO:0005178|integrin binding; GO:0008201|heparin binding; GO:0008237|metallopeptidase activity; GO:0008270|zinc ion binding; GO:0050840|extracellular matrix binding	ko:K08620|ADAMTS5	--	2634	XP_425541.6	XP_425541.6 A disintegrin and metalloproteinase with thrombospondin motifs 5 [Gallus gallus]	sp|Q9UNA0|ATS5_HUMAN	sp|Q9UNA0|ATS5_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 5 OS=Homo sapiens GN=ADAMTS5 PE=1 SV=2	9031.ENSGALP00000025424	"ADAM metallopeptidase with thrombospondin type 1 motif, 5 (aggrecanase-2)"	_	KOG3538	_	PF05986.11|ADAM_spacer1|ADAM-TS Spacer 1|ENSGALT00000025470|m.3010:679-798;PF01421.16|Reprolysin|Reprolysin (M12B) family zinc metalloprotease|ENSGALT00000025470|m.3010:214-422;PF13688.3|Reprolysin_5|Metallo-peptidase family M12|ENSGALT00000025470|m.3010:212-372;PF13582.3|Reprolysin_3|Metallo-peptidase family M12B Reprolysin-like|ENSGALT00000025470|m.3010:254-367;PF01562.16|Pep_M12B_propep|Reprolysin family propeptide|ENSGALT00000025470|m.3010:100-151;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000025470|m.3010:518-567;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000025470|m.3010:828-877;PF13583.3|Reprolysin_4|Metallo-peptidase family M12B Reprolysin-like|ENSGALT00000025470|m.3010:295-404
ENSGALG00000015810	0.378867496	0.841912966	-1.131427397	0.006633457	0.012127714	down	yes	0.280122749	0.472388359	0.384091381	0.811331017	0.786591416	0.927816465	3	76468737	76481009	-	ENSGALG00000015810	protein_coding	GO:0003341|cilium movement; GO:0035082|axoneme assembly	GO:0001534|radial spoke; GO:0005737|cytoplasm; GO:0031514|motile cilium	--	--	--	1881	XP_419848.1	XP_419848.1 cilia- and flagella-associated protein 206 [Gallus gallus]	sp|Q29RL1|CF206_BOVIN	sp|Q29RL1|CF206_BOVIN Cilia- and flagella-associated protein 206 OS=Bos taurus GN=CFAP206 PE=2 SV=2	_	_	_	_	_	PF12018.5|DUF3508|Domain of unknown function (DUF3508)|ENSGALT00000025491|m.12573:214-494
ENSGALG00000015836	5.447033157	13.53923048	-1.312022203	2.30E-56	1.01E-54	down	yes	5.251119756	5.778328745	5.311650968	12.65996344	14.30043587	13.65729214	3	77469083	77515525	+	CEP162	protein_coding	GO:0060271|cilium assembly	GO:0005634|nucleus; GO:0005814|centriole; GO:0005879|axonemal microtubule	--	ko:K16809|QN1	--	5236	XP_004940457.1	XP_004940457.1 centrosomal protein of 162 kDa isoform X1 [Gallus gallus]	sp|Q91365|CE162_COTCO	sp|Q91365|CE162_COTCO Centrosomal protein of 162 kDa (Fragment) OS=Coturnix coturnix GN=CEP162 PE=1 SV=1	_	_	_	_	_	_
ENSGALG00000015842	4.973459343	10.90771728	-1.13145178	5.72E-38	1.32E-36	down	yes	5.242087839	4.968817741	4.709472448	10.59081196	11.12702843	11.00531144	1	105805720	105885857	-	TIAM1	protein_coding	"GO:0003300|cardiac muscle hypertrophy; GO:0006915|apoptotic process; GO:0007160|cell-matrix adhesion; GO:0008284|positive regulation of cell population proliferation; GO:0010717|regulation of epithelial to mesenchymal transition; GO:0010718|positive regulation of epithelial to mesenchymal transition; GO:0016477|cell migration; GO:0016601|Rac protein signal transduction; GO:0030335|positive regulation of cell migration; GO:0032092|positive regulation of protein binding; GO:0035023|regulation of Rho protein signal transduction; GO:0042220|response to cocaine; GO:0043065|positive regulation of apoptotic process; GO:0043507|positive regulation of JUN kinase activity; GO:0048013|ephrin receptor signaling pathway; GO:0050772|positive regulation of axonogenesis; GO:0051056|regulation of small GTPase mediated signal transduction; GO:0060071|Wnt signaling pathway, planar cell polarity pathway; GO:0061003|positive regulation of dendritic spine morphogenesis; GO:0061178|regulation of insulin secretion involved in cellular response to glucose stimulus; GO:0070372|regulation of ERK1 and ERK2 cascade; GO:0072657|protein localization to membrane; GO:0090630|activation of GTPase activity; GO:0098989|NMDA selective glutamate receptor signaling pathway; GO:1904268|positive regulation of Schwann cell chemotaxis; GO:1904338|regulation of dopaminergic neuron differentiation; GO:1905274|regulation of modification of postsynaptic actin cytoskeleton; GO:1990138|neuron projection extension; GO:2000050|regulation of non-canonical Wnt signaling pathway"	GO:0005634|nucleus; GO:0005829|cytosol; GO:0005874|microtubule; GO:0005886|plasma membrane; GO:0005911|cell-cell junction; GO:0014069|postsynaptic density; GO:0031234|extrinsic component of cytoplasmic side of plasma membrane; GO:0032587|ruffle membrane; GO:0043025|neuronal cell body; GO:0043197|dendritic spine; GO:0044291|cell-cell contact zone; GO:0044295|axonal growth cone; GO:0044304|main axon	GO:0005085|guanyl-nucleotide exchange factor activity; GO:0005089|Rho guanyl-nucleotide exchange factor activity; GO:0008017|microtubule binding; GO:0008289|lipid binding; GO:0019900|kinase binding; GO:0030676|Rac guanyl-nucleotide exchange factor activity; GO:0030971|receptor tyrosine kinase binding	ko:K05731|TIAM1	ko04014|Ras signaling pathway; ko04015|Rap1 signaling pathway; ko04024|cAMP signaling pathway; ko04062|Chemokine signaling pathway; ko04530|Tight junction; ko04810|Regulation of actin cytoskeleton; ko05205|Proteoglycans in cancer	4785	XP_416699.2	XP_416699.2 T-lymphoma invasion and metastasis-inducing protein 1 isoform X2 [Gallus gallus]	sp|Q13009|TIAM1_HUMAN	sp|Q13009|TIAM1_HUMAN T-lymphoma invasion and metastasis-inducing protein 1 OS=Homo sapiens GN=TIAM1 PE=1 SV=2	9031.ENSGALP00000025495	T-cell lymphoma invasion and metastasis 1	COG5422	KOG3519	_	PF00621.17|RhoGEF|RhoGEF domain|ENSGALT00000064200|m.3031:1046-1234;PF00169.26|PH|PH domain|ENSGALT00000064200|m.3031:448-548;PF00169.26|PH|PH domain|ENSGALT00000064200|m.3031:1290-1396;PF02196.12|RBD|Raf-like Ras-binding domain|ENSGALT00000064200|m.3031:769-840;PF15410.3|PH_9|Pleckstrin homology domain|ENSGALT00000064200|m.3031:447-549
ENSGALG00000015878	3.42975647	10.96560068	-1.673921566	2.89E-33	5.41E-32	down	yes	2.964016263	3.226394804	4.098858342	11.03760254	11.81274965	10.04644986	3	79409441	79421209	+	LCA5	protein_coding	GO:0015031|protein transport	GO:0005737|cytoplasm; GO:0005815|microtubule organizing center; GO:0005929|cilium	GO:0044877|protein-containing complex binding	--	--	2311	XP_419870.1	XP_419870.1 lebercilin [Gallus gallus]	sp|Q86VQ0|LCA5_HUMAN	sp|Q86VQ0|LCA5_HUMAN Lebercilin OS=Homo sapiens GN=LCA5 PE=1 SV=2	9031.ENSGALP00000025547	Leber congenital amaurosis 5	_	_	NOG71875	PF15619.3|Lebercilin|Ciliary protein causing Leber congenital amaurosis disease|ENSGALT00000025594|m.12664:103-295
ENSGALG00000015879	1.399332593	3.986479931	-1.503717726	5.51E-12	2.89E-11	down	yes	1.408284278	1.129966129	1.659747373	4.617590448	3.594041119	3.747808225	1	106074483	106129164	+	HUNK	protein_coding	--	--	GO:0004674|protein serine/threonine kinase activity; GO:0005524|ATP binding	ko:K08797|HUNK	--	1983	XP_015155202.1	XP_015155202.1 hormonally up-regulated neu tumor-associated kinase isoform X2 [Gallus gallus]	sp|Q5XHI9|HUNKA_XENLA	sp|Q5XHI9|HUNKA_XENLA Hormonally up-regulated neu tumor-associated kinase homolog A OS=Xenopus laevis GN=hunk-a PE=2 SV=1	9031.ENSGALP00000025548	annotation not avaliable	COG0515	KOG0583	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000025595|m.3036:68-324;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000025595|m.3036:69-317;PF14531.3|Kinase-like|Kinase-like|ENSGALT00000025595|m.3036:150-269;PF06293.11|Kdo|Lipopolysaccharide kinase (Kdo/WaaP) family|ENSGALT00000025595|m.3036:153-209;PF01163.19|RIO1|RIO1 family|ENSGALT00000025595|m.3036:141-210
ENSGALG00000015977	10.50321762	25.02360831	-1.251661974	4.01E-21	4.02E-20	down	yes	11.81573057	8.885439915	10.80848236	28.26224309	19.71080443	27.09777742	4	88402221	88446642	-	SMOX	protein_coding	GO:0006596|polyamine biosynthetic process; GO:0006598|polyamine catabolic process; GO:0046208|spermine catabolic process	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0031965|nuclear membrane; GO:0043231|intracellular membrane-bounded organelle	GO:0046592|polyamine oxidase activity; GO:0052894|norspermine:oxygen oxidoreductase activity; GO:0052895|N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity; GO:0052901|spermine:oxygen oxidoreductase (spermidine-forming) activity	"ko:K12259|SMOX,PAO5"	ko00330|Arginine and proline metabolism; ko00410|beta-Alanine metabolism	2087	XP_420872.3	XP_420872.3 spermine oxidase isoform X2 [Gallus gallus]	sp|Q9NWM0|SMOX_HUMAN	sp|Q9NWM0|SMOX_HUMAN Spermine oxidase OS=Homo sapiens GN=SMOX PE=1 SV=1	_	_	_	_	_	PF01593.21|Amino_oxidase|Flavin containing amine oxidoreductase|ENSGALT00000025747|m.1641:34-524;PF13450.3|NAD_binding_8|NAD(P)-binding Rossmann-like domain|ENSGALT00000025747|m.1641:29-93;PF01266.21|DAO|FAD dependent oxidoreductase|ENSGALT00000025747|m.1641:26-62;PF00890.21|FAD_binding_2|FAD binding domain|ENSGALT00000025747|m.1641:27-65
ENSGALG00000016001	1.240172361	4.20388439	-1.753023721	3.91E-16	2.84E-15	down	yes	1.323481045	1.010809846	1.386226191	3.775172896	4.372837465	4.463642809	4	88682845	88689142	-	LZTS3	protein_coding	GO:0061001|regulation of dendritic spine morphogenesis	GO:0005737|cytoplasm; GO:0005856|cytoskeleton; GO:0014069|postsynaptic density; GO:0030054|cell junction; GO:0045202|synapse; GO:0045211|postsynaptic membrane	--	--	--	1911	XP_420876.4	XP_420876.4 LOW QUALITY PROTEIN: leucine zipper putative tumor suppressor 3 [Gallus gallus]	sp|O60299|LZTS3_HUMAN	sp|O60299|LZTS3_HUMAN Leucine zipper putative tumor suppressor 3 OS=Homo sapiens GN=LZTS3 PE=2 SV=1	9031.ENSGALP00000025734	ProSAPiP1 protein	_	_	NOG137465	PF06818.12|Fez1|Fez1|ENSGALT00000077018|m.1660:397-604
ENSGALG00000016059	7.543763893	31.17506004	-2.045587441	4.79E-63	2.58E-61	down	yes	9.395044566	5.812635549	7.423611565	30.47087026	30.6004395	32.45387035	1	109131453	109144592	+	ETS2	protein_coding	"GO:0001569|branching involved in blood vessel morphogenesis; GO:0001712|ectodermal cell fate commitment; GO:0006351|transcription, DNA-templated; GO:0006357|regulation of transcription by RNA polymerase II; GO:0007498|mesoderm development; GO:0030154|cell differentiation; GO:0045893|positive regulation of transcription, DNA-templated; GO:0060982|coronary artery morphogenesis; GO:0090009|primitive streak formation"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005829|cytosol; GO:0005886|plasma membrane	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0001227|DNA-binding transcription repressor activity, RNA polymerase II-specific; GO:0019904|protein domain specific binding"	"ko:K02678|ETS,pnt"	ko04013|MAPK signaling pathway - fly; ko04014|Ras signaling pathway; ko04320|Dorso-ventral axis formation; ko05166|HTLV-I infection	1930	NP_990643.1	NP_990643.1 protein C-ets-2 [Gallus gallus]	sp|P10157|ETS2_CHICK	sp|P10157|ETS2_CHICK Protein C-ets-2 OS=Gallus gallus GN=ETS2 PE=2 SV=1	_	_	_	_	_	PF00178.19|Ets|Ets-domain|ENSGALT00000094617|m.3122:374-453;PF02198.13|SAM_PNT|Sterile alpha motif (SAM)/Pointed domain|ENSGALT00000094617|m.3122:91-172
ENSGALG00000016086	0.984817522	2.716879309	-1.454747025	1.11E-05	3.10E-05	down	yes	1.497679535	0.76534238	0.691430651	2.646035266	2.835988836	2.668613824	4	89672386	89673546	+	EGR4	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0071363|cellular response to growth factor stimulus"	GO:0005634|nucleus	GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding; GO:0043565|sequence-specific DNA binding; GO:0046872|metal ion binding	ko:K12498|EGR4	--	1161	XP_420888.1	XP_420888.1 early growth response protein 4 [Gallus gallus]	sp|Q00911|EGR4_RAT	sp|Q00911|EGR4_RAT Early growth response protein 4 OS=Rattus norvegicus GN=Egr4 PE=2 SV=1	9031.ENSGALP00000025873	early growth response 4	COG5048	KOG1721	_	PF13894.3|zf-C2H2_4|C2H2-type zinc finger|ENSGALT00000025920|m.1683:310-332
ENSGALG00000016142	1.122997334	2.8460334	-1.333868385	8.76E-11	4.16E-10	down	yes	1.014373908	1.267112303	1.087505791	3.165492567	2.904848864	2.46775877	1	110239567	110260524	+	MX1	protein_coding	GO:0000266|mitochondrial fission; GO:0003374|dynamin family protein polymerization involved in mitochondrial fission; GO:0045087|innate immune response; GO:0051607|defense response to virus; GO:0061025|membrane fusion	GO:0031966|mitochondrial membrane	GO:0003924|GTPase activity; GO:0005525|GTP binding; GO:0008017|microtubule binding	ko:K14754|MX1	ko05162|Measles; ko05164|Influenza A	2679	ABQ43211.1	"ABQ43211.1 Mx protein, partial [Gallus gallus]"	sp|Q90597|MX_CHICK	sp|Q90597|MX_CHICK Interferon-induced GTP-binding protein Mx OS=Gallus gallus GN=MX PE=2 SV=1	9031.ENSGALP00000025952	Interferon-induced GTP-binding protein Mx (Interferon-inducible Mx protein); Does not show a [...] 	COG0699	KOG0446	_	PF01031.17|Dynamin_M|Dynamin central region|ENSGALT00000025999|m.3147:304-590;PF00350.20|Dynamin_N|Dynamin family|ENSGALT00000025999|m.3147:117-292;PF02212.15|GED|Dynamin GTPase effector domain|ENSGALT00000025999|m.3147:616-701;PF01926.20|MMR_HSR1|50S ribosome-binding GTPase|ENSGALT00000025999|m.3147:117-273
ENSGALG00000016186	1.849608127	3.876281907	-1.06339192	3.73E-08	1.39E-07	down	yes	1.311460267	2.07821855	2.159145565	3.803210109	4.015569616	3.810065995	1	110824235	110867346	+	PDE9A	protein_coding	GO:0010613|positive regulation of cardiac muscle hypertrophy; GO:0019934|cGMP-mediated signaling; GO:0046068|cGMP metabolic process; GO:0046069|cGMP catabolic process	GO:0005783|endoplasmic reticulum; GO:0005794|Golgi apparatus; GO:0005829|cytosol; GO:0032587|ruffle membrane; GO:0042383|sarcolemma; GO:0043204|perikaryon; GO:0048471|perinuclear region of cytoplasm	"GO:0046872|metal ion binding; GO:0047555|3',5'-cyclic-GMP phosphodiesterase activity"	ko:K13761|PDE9	ko00230|Purine metabolism	2491	XP_416748.3	"XP_416748.3 high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform X1 [Gallus gallus]"	sp|O70628|PDE9A_MOUSE	"sp|O70628|PDE9A_MOUSE High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A OS=Mus musculus GN=Pde9a PE=1 SV=1"	9031.ENSGALP00000026036	phosphodiesterase 9A	_	KOG3689	_	PF00233.16|PDEase_I|3'5'-cyclic nucleotide phosphodiesterase|ENSGALT00000026084|m.3179:251-479
ENSGALG00000016221	0.311926743	1.026646613	-1.687119837	4.52E-06	1.33E-05	down	yes	0.18766118	0.366915574	0.381203475	1.050983036	1.113289662	0.915667141	1	112372336	112431837	+	EFHC2	protein_coding	--	GO:0005623|cell	--	--	--	2527	NP_001032918.2	NP_001032918.2 EF-hand domain-containing family member C2 [Gallus gallus]	sp|Q32TG3|EFHC2_CHICK	sp|Q32TG3|EFHC2_CHICK EF-hand domain-containing family member C2 OS=Gallus gallus GN=EFHC2 PE=2 SV=1	9031.ENSGALP00000026102	EF-hand domain-containing family member C2 	_	KOG0043	_	PF06565.9|DUF1126|Repeat of unknown function (DUF1126)|ENSGALT00000026150|m.3220:119-151;PF06565.9|DUF1126|Repeat of unknown function (DUF1126)|ENSGALT00000026150|m.3220:266-299;PF06565.9|DUF1126|Repeat of unknown function (DUF1126)|ENSGALT00000026150|m.3220:468-500
ENSGALG00000016262	1.056836904	0.448453369	1.218492731	0.000822148	0.001754507	up	yes	0.887055372	0.854797982	1.428657357	0.333664271	0.52122892	0.490466917	1	114494391	114509421	-	XK	protein_coding	GO:0006810|transport; GO:0006865|amino acid transport; GO:0006874|cellular calcium ion homeostasis; GO:0008361|regulation of cell size; GO:0010961|cellular magnesium ion homeostasis; GO:0031133|regulation of axon diameter; GO:0042552|myelination; GO:0048741|skeletal muscle fiber development	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0005215|transporter activity	ko:K19522|XK	--	2079	XP_021263585.1	XP_021263585.1 membrane transport protein XK [Numida meleagris]	sp|P51811|XK_HUMAN	sp|P51811|XK_HUMAN Membrane transport protein XK OS=Homo sapiens GN=XK PE=1 SV=5	9031.ENSGALP00000026173	membrane transport protein XK 	_	KOG4790	_	PF09815.6|XK-related|XK-related protein|ENSGALT00000026223|m.3296:30-399
ENSGALG00000016266	6.830931841	3.288064	1.052573461	1.78E-20	1.72E-19	up	yes	7.140032127	7.011404589	6.341358807	2.942639072	3.744037089	3.177515838	1	114579211	114609539	-	PRRG1	protein_coding	--	GO:0005576|extracellular region; GO:0016021|integral component of membrane	GO:0005509|calcium ion binding	--	--	4937	XP_015157319.1	XP_015157319.1 transmembrane gamma-carboxyglutamic acid protein 1 isoform X2 [Gallus gallus]	sp|A7Z070|TMG1_BOVIN	sp|A7Z070|TMG1_BOVIN Transmembrane gamma-carboxyglutamic acid protein 1 OS=Bos taurus GN=PRRG1 PE=2 SV=1	9031.ENSGALP00000026179	proline rich Gla (G-carboxyglutamic acid) 1	_	KOG3627	NOG113953	PF00594.17|Gla|Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain|ENSGALT00000026229|m.3300:147-187
ENSGALG00000016313	39.06778017	87.65100488	-1.1655867	4.04E-79	3.23E-77	down	yes	39.79901517	38.03042808	39.37389727	85.9756841	91.43685099	85.54047956	3	88184018	88215580	+	GCLC	protein_coding	"GO:0006534|cysteine metabolic process; GO:0006536|glutamate metabolic process; GO:0006750|glutathione biosynthetic process; GO:0006979|response to oxidative stress; GO:0007568|aging; GO:0007584|response to nutrient; GO:0008637|apoptotic mitochondrial changes; GO:0009408|response to heat; GO:0009410|response to xenobiotic stimulus; GO:0009725|response to hormone; GO:0014823|response to activity; GO:0019852|L-ascorbic acid metabolic process; GO:0031397|negative regulation of protein ubiquitination; GO:0032436|positive regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0032869|cellular response to insulin stimulus; GO:0035729|cellular response to hepatocyte growth factor stimulus; GO:0043066|negative regulation of apoptotic process; GO:0043524|negative regulation of neuron apoptotic process; GO:0044344|cellular response to fibroblast growth factor stimulus; GO:0044752|response to human chorionic gonadotropin; GO:0045454|cell redox homeostasis; GO:0045892|negative regulation of transcription, DNA-templated; GO:0046685|response to arsenic-containing substance; GO:0046686|response to cadmium ion; GO:0051409|response to nitrosative stress; GO:0051900|regulation of mitochondrial depolarization; GO:0070555|response to interleukin-1; GO:0071260|cellular response to mechanical stimulus; GO:0071333|cellular response to glucose stimulus; GO:0071372|cellular response to follicle-stimulating hormone stimulus; GO:0097069|cellular response to thyroxine stimulus; GO:0097746|regulation of blood vessel diameter; GO:2000490|negative regulation of hepatic stellate cell activation; GO:2001237|negative regulation of extrinsic apoptotic signaling pathway"	GO:0005829|cytosol; GO:0017109|glutamate-cysteine ligase complex	GO:0000287|magnesium ion binding; GO:0004357|glutamate-cysteine ligase activity; GO:0005524|ATP binding; GO:0016595|glutamate binding; GO:0043531|ADP binding; GO:0046982|protein heterodimerization activity; GO:0050662|coenzyme binding	ko:K11204|GCLC	ko00270|Cysteine and methionine metabolism; ko00480|Glutathione metabolism; ko01100|Metabolic pathways; ko04212|Longevity regulating pathway - worm; ko04216|Ferroptosis	2438	XP_419910.4	XP_419910.4 glutamate--cysteine ligase catalytic subunit [Gallus gallus]	sp|P48506|GSH1_HUMAN	sp|P48506|GSH1_HUMAN Glutamate--cysteine ligase catalytic subunit OS=Homo sapiens GN=GCLC PE=1 SV=2	59729.ENSTGUP00000013244	Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2)(Gamma-glutamylcysteine synthetase) [...] 	_	KOG3754	_	PF03074.13|GCS|Glutamate-cysteine ligase|ENSGALT00000026320|m.12834:269-641
ENSGALG00000016332	11.24511126	23.15520578	-1.041379179	4.33E-26	5.69E-25	down	yes	10.38790193	11.63127509	11.71615677	21.31395691	24.75642309	23.39523734	3	88558041	88679655	-	MCPH1	protein_coding	GO:0021987|cerebral cortex development	GO:0005737|cytoplasm; GO:0005815|microtubule organizing center	--	ko:K19403|MCPH1	--	1963	XP_025004230.1	XP_025004230.1 microcephalin isoform X1 [Gallus gallus]	sp|P61593|MCPH1_PANTR	sp|P61593|MCPH1_PANTR Microcephalin OS=Pan troglodytes GN=MCPH1 PE=3 SV=1	_	_	_	_	_	"PF16589.2|BRCT_2|BRCT domain, a BRCA1 C-terminus domain|ENSGALT00000086126|m.12860:517-585;PF00533.23|BRCT|BRCA1 C Terminus (BRCT) domain|ENSGALT00000086126|m.12860:99-154;PF00533.23|BRCT|BRCA1 C Terminus (BRCT) domain|ENSGALT00000086126|m.12860:428-468;PF12738.4|PTCB-BRCT|twin BRCT domain|ENSGALT00000086126|m.12860:87-150"
ENSGALG00000016342	0.131718082	0.604324344	-2.115976706	1.73E-08	6.66E-08	down	yes	0.099680456	0.211948811	0.08352498	0.742393535	0.540098608	0.530480889	3	90705369	90802601	-	MYOM2	protein_coding	GO:0006941|striated muscle contraction; GO:0007015|actin filament organization; GO:0045214|sarcomere organization; GO:0071688|striated muscle myosin thick filament assembly	GO:0005859|muscle myosin complex; GO:0030018|Z disc; GO:0031430|M band	GO:0008307|structural constituent of muscle; GO:0051015|actin filament binding; GO:0051371|muscle alpha-actinin binding; GO:0097493|structural molecule activity conferring elasticity	--	--	5214	XP_015140305.1	"XP_015140305.1 M-protein, striated muscle isoform X1 [Gallus gallus]"	sp|Q02173|MPSF_CHICK	"sp|Q02173|MPSF_CHICK M-protein, striated muscle OS=Gallus gallus PE=2 SV=1"	9031.ENSGALP00000026310	"M-protein, striated muscle ; Is a structural constituent of myofibrillar M-band in striated muscle"	_	KOG0613	_	PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000026360|m.12871:373-457;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000026360|m.12871:501-585;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000026360|m.12871:601-684;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000026360|m.12871:701-785;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000026360|m.12871:805-887;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000026360|m.12871:142-234;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000026360|m.12871:270-360;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000026360|m.12871:1337-1423;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000026360|m.12871:142-221;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000026360|m.12871:1342-1410;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000026360|m.12871:1343-1421;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000026360|m.12871:1342-1419
ENSGALG00000016421	5.371438283	11.6400593	-1.114273583	1.56E-10	7.26E-10	down	yes	4.206583851	4.918880368	6.98885063	10.18945926	11.54542477	13.18529387	3	96183941	96191112	-	ITGB1BP1	protein_coding	"GO:0002043|blood vessel endothelial cell proliferation involved in sprouting angiogenesis; GO:0006351|transcription, DNA-templated; GO:0006469|negative regulation of protein kinase activity; GO:0006933|negative regulation of cell adhesion involved in substrate-bound cell migration; GO:0007160|cell-matrix adhesion; GO:0007219|Notch signaling pathway; GO:0007229|integrin-mediated signaling pathway; GO:0008284|positive regulation of cell population proliferation; GO:0008285|negative regulation of cell population proliferation; GO:0010595|positive regulation of endothelial cell migration; GO:0010764|negative regulation of fibroblast migration; GO:0015031|protein transport; GO:0016477|cell migration; GO:0030154|cell differentiation; GO:0031214|biomineral tissue development; GO:0032091|negative regulation of protein binding; GO:0032148|activation of protein kinase B activity; GO:0033622|integrin activation; GO:0033628|regulation of cell adhesion mediated by integrin; GO:0035148|tube formation; GO:0035556|intracellular signal transduction; GO:0035924|cellular response to vascular endothelial growth factor stimulus; GO:0043087|regulation of GTPase activity; GO:0043113|receptor clustering; GO:0044344|cellular response to fibroblast growth factor stimulus; GO:0045747|positive regulation of Notch signaling pathway; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0051451|myoblast migration; GO:0051496|positive regulation of stress fiber assembly; GO:0051781|positive regulation of cell division; GO:0051894|positive regulation of focal adhesion assembly; GO:0051895|negative regulation of focal adhesion assembly; GO:0051897|positive regulation of protein kinase B signaling; GO:0070373|negative regulation of ERK1 and ERK2 cascade; GO:0090051|negative regulation of cell migration involved in sprouting angiogenesis; GO:0090314|positive regulation of protein targeting to membrane; GO:0090315|negative regulation of protein targeting to membrane; GO:0097746|regulation of blood vessel diameter; GO:1900025|negative regulation of substrate adhesion-dependent cell spreading; GO:2001044|regulation of integrin-mediated signaling pathway"	GO:0001726|ruffle; GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005856|cytoskeleton; GO:0005886|plasma membrane; GO:0016020|membrane; GO:0030027|lamellipodium; GO:0048471|perinuclear region of cytoplasm; GO:0070062|extracellular exosome; GO:0071944|cell periphery	GO:0005092|GDP-dissociation inhibitor activity; GO:0005178|integrin binding; GO:0019901|protein kinase binding; GO:0044877|protein-containing complex binding	ko:K20058|ITGB1BP1	--	1167	PKK33399.1	"PKK33399.1 integrin beta 1 binding protein 1, transcript variant X4, partial [Columba livia]"	sp|O14713|ITBP1_HUMAN	sp|O14713|ITBP1_HUMAN Integrin beta-1-binding protein 1 OS=Homo sapiens GN=ITGB1BP1 PE=1 SV=1	9031.ENSGALP00000026439	integrin beta 1 binding protein 1	_	_	NOG45114	_
ENSGALG00000016456	12.96881483	26.84533589	-1.049050118	2.55E-53	1.03E-51	down	yes	13.00169731	13.17541012	12.72933705	26.90840281	26.84188606	26.78571882	3	97402679	97470693	+	LPIN1	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006642|triglyceride mobilization; GO:0006646|phosphatidylethanolamine biosynthetic process; GO:0006656|phosphatidylcholine biosynthetic process; GO:0007077|mitotic nuclear envelope disassembly; GO:0009062|fatty acid catabolic process; GO:0019432|triglyceride biosynthetic process; GO:0031100|animal organ regeneration; GO:0032869|cellular response to insulin stimulus; GO:0045944|positive regulation of transcription by RNA polymerase II"	GO:0005634|nucleus; GO:0005635|nuclear envelope; GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005741|mitochondrial outer membrane; GO:0005789|endoplasmic reticulum membrane; GO:0005829|cytosol; GO:0031965|nuclear membrane	GO:0003713|transcription coactivator activity; GO:0008195|phosphatidate phosphatase activity	ko:K15728|LPIN	ko00561|Glycerolipid metabolism; ko00564|Glycerophospholipid metabolism; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites	3153	XP_015131579.1	XP_015131579.1 phosphatidate phosphatase LPIN1 isoform X6 [Gallus gallus]	sp|Q14693|LPIN1_HUMAN	sp|Q14693|LPIN1_HUMAN Phosphatidate phosphatase LPIN1 OS=Homo sapiens GN=LPIN1 PE=1 SV=2	9031.ENSGALP00000026501	lipin 1	COG5083	KOG2116	_	"PF08235.10|LNS2|LNS2 (Lipin/Ned1/Smp2)|ENSGALT00000071329|m.12988:638-863;PF04571.11|Lipin_N|lipin, N-terminal conserved region|ENSGALT00000071329|m.12988:1-107;PF16876.2|Lipin_mid|Lipin/Ned1/Smp2 multi-domain protein middle domain|ENSGALT00000071329|m.12988:471-564"
ENSGALG00000016462	1.641108412	6.509255256	-1.981272313	2.32E-23	2.64E-22	down	yes	1.63861626	1.404274518	1.880434457	7.340317493	4.679546863	7.507901412	3	99207484	99211831	+	MYCN	protein_coding	--	GO:0005634|nucleus	GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity; GO:0046983|protein dimerization activity	"ko:K09109|NMYC,MYCN"	ko05202|Transcriptional misregulation in cancer	2286	NP_001026262.2	NP_001026262.2 N-myc proto-oncogene protein [Gallus gallus]	sp|P18444|MYCN_CHICK	sp|P18444|MYCN_CHICK N-myc proto-oncogene protein OS=Gallus gallus GN=MYCN PE=3 SV=1	9031.ENSGALP00000036097	N-myc proto-oncogene protein 	_	_	NOG83719	PF01056.15|Myc_N|Myc amino-terminal region|ENSGALT00000107250|m.13006:1-349;PF00010.23|HLH|Helix-loop-helix DNA-binding domain|ENSGALT00000107250|m.13006:359-411
ENSGALG00000016477	1.43474112	3.024075901	-1.070446174	1.58E-12	8.67E-12	down	yes	1.447417869	1.396378999	1.460426491	2.975336566	2.907435686	3.18945545	3	101354461	101391431	-	WDR35	protein_coding	GO:0009636|response to toxic substance; GO:0010629|negative regulation of gene expression; GO:0032496|response to lipopolysaccharide; GO:0035721|intraciliary retrograde transport; GO:0043065|positive regulation of apoptotic process; GO:0043280|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0045019|negative regulation of nitric oxide biosynthetic process; GO:0060271|cilium assembly; GO:0061512|protein localization to cilium; GO:0071333|cellular response to glucose stimulus; GO:0071356|cellular response to tumor necrosis factor; GO:0090200|positive regulation of release of cytochrome c from mitochondria; GO:0097421|liver regeneration; GO:0097756|negative regulation of blood vessel diameter; GO:1901555|response to paclitaxel; GO:1905705|cellular response to paclitaxel; GO:1990830|cellular response to leukemia inhibitory factor	GO:0005737|cytoplasm; GO:0005813|centrosome; GO:0005929|cilium; GO:0005930|axoneme; GO:0030991|intraciliary transport particle A; GO:0036064|ciliary basal body	GO:0035091|phosphatidylinositol binding	"ko:K19674|WDR35,IFT121"	--	4117	XP_003641123.1	XP_003641123.1 WD repeat-containing protein 35 isoform X2 [Gallus gallus]	sp|A6N6J5|WDR35_RAT	sp|A6N6J5|WDR35_RAT WD repeat-containing protein 35 OS=Rattus norvegicus GN=Wdr35 PE=1 SV=1	9031.ENSGALP00000026532	WD repeat domain 35	_	KOG2041	_	PF12894.4|ANAPC4_WD40|Anaphase-promoting complex subunit 4 WD40 domain|ENSGALT00000063531|m.13048:121-193
ENSGALG00000016485	10.65359875	40.07360083	-1.910317715	1.87E-94	2.04E-92	down	yes	12.36604575	9.745150622	9.849599885	40.58149185	39.8665558	39.77275482	3	101681364	101683698	+	RHOB	protein_coding	GO:0000281|mitotic cytokinesis; GO:0001525|angiogenesis; GO:0006886|intracellular protein transport; GO:0006915|apoptotic process; GO:0007155|cell adhesion; GO:0007264|small GTPase mediated signal transduction; GO:0008333|endosome to lysosome transport; GO:0010595|positive regulation of endothelial cell migration; GO:0030154|cell differentiation; GO:0030336|negative regulation of cell migration; GO:0043065|positive regulation of apoptotic process; GO:0045766|positive regulation of angiogenesis; GO:0045786|negative regulation of cell cycle; GO:0061154|endothelial tube morphogenesis; GO:0070301|cellular response to hydrogen peroxide; GO:0071479|cellular response to ionizing radiation	GO:0005634|nucleus; GO:0005769|early endosome; GO:0005886|plasma membrane; GO:0005925|focal adhesion; GO:0031902|late endosome membrane; GO:0032154|cleavage furrow; GO:0070062|extracellular exosome	GO:0003924|GTPase activity; GO:0005525|GTP binding; GO:0019003|GDP binding	ko:K07856|RHOB	--	2335	OWK63298.1	OWK63298.1 Rho-related GTP-binding protein RhoB [Lonchura striata domestica]	sp|Q3ZBW5|RHOB_BOVIN	sp|Q3ZBW5|RHOB_BOVIN Rho-related GTP-binding protein RhoB OS=Bos taurus GN=RHOB PE=2 SV=1	9031.ENSGALP00000026544	"ras homolog gene family, member B "	COG1100	KOG0393	_	"PF00071.19|Ras|Ras family|ENSGALT00000026595|m.13060:7-179;PF08477.10|Roc|Ras of Complex, Roc, domain of DAPkinase|ENSGALT00000026595|m.13060:7-120;PF00025.18|Arf|ADP-ribosylation factor family|ENSGALT00000026595|m.13060:7-172"
ENSGALG00000016492	7.296263464	3.302322382	1.141290684	1.69E-29	2.57E-28	up	yes	6.853063481	7.54020044	7.495526471	2.911861791	3.598891778	3.396213578	3	102274603	102281938	+	TDRD15	protein_coding	--	--	--	ko:K18405|TDRD1_4_6_7	--	6051	XP_015140542.1	XP_015140542.1 tudor domain-containing protein 15 isoform X1 [Gallus gallus]	sp|B5MCY1|TDR15_HUMAN	sp|B5MCY1|TDR15_HUMAN Tudor domain-containing protein 15 OS=Homo sapiens GN=TDRD15 PE=2 SV=1	9031.ENSGALP00000036063	similar to tudor domain containing 6 protein	_	KOG2039	_	PF00567.21|TUDOR|Tudor domain|ENSGALT00000026603|m.13069:67-146;PF00567.21|TUDOR|Tudor domain|ENSGALT00000026603|m.13069:270-389;PF00567.21|TUDOR|Tudor domain|ENSGALT00000026603|m.13069:517-636;PF00567.21|TUDOR|Tudor domain|ENSGALT00000026603|m.13069:795-911;PF00567.21|TUDOR|Tudor domain|ENSGALT00000026603|m.13069:1006-1126;PF00567.21|TUDOR|Tudor domain|ENSGALT00000026603|m.13069:1348-1467;PF00567.21|TUDOR|Tudor domain|ENSGALT00000026603|m.13069:1593-1704;PF00567.21|TUDOR|Tudor domain|ENSGALT00000026603|m.13069:1802-1917
ENSGALG00000016508	2.51056452	5.386683705	-1.098326251	3.52E-09	1.45E-08	down	yes	2.718191105	2.504000612	2.309501843	5.374378081	5.196000793	5.589672242	3	104332544	104340810	-	ENSGALG00000016508	protein_coding	GO:0006898|receptor-mediated endocytosis; GO:0008203|cholesterol metabolic process; GO:0031623|receptor internalization; GO:0034383|low-density lipoprotein particle clearance; GO:0042632|cholesterol homeostasis; GO:0042982|amyloid precursor protein metabolic process; GO:0043393|regulation of protein binding; GO:0048260|positive regulation of receptor-mediated endocytosis; GO:0090118|receptor-mediated endocytosis involved in cholesterol transport; GO:1903076|regulation of protein localization to plasma membrane; GO:1905602|positive regulation of receptor-mediated endocytosis involved in cholesterol transport	GO:0005737|cytoplasm; GO:0005769|early endosome; GO:0005829|cytosol; GO:0005883|neurofilament; GO:0009898|cytoplasmic side of plasma membrane; GO:0009925|basal plasma membrane; GO:0030121|AP-1 adaptor complex; GO:0030122|AP-2 adaptor complex; GO:0030424|axon; GO:0055037|recycling endosome	"GO:0001540|amyloid-beta binding; GO:0001784|phosphotyrosine residue binding; GO:0005102|signaling receptor binding; GO:0005546|phosphatidylinositol-4,5-bisphosphate binding; GO:0030159|receptor signaling complex adaptor activity; GO:0030276|clathrin binding; GO:0035591|signaling adaptor activity; GO:0035612|AP-2 adaptor complex binding; GO:0035615|clathrin adaptor activity; GO:0050750|low-density lipoprotein particle receptor binding"	"ko:K12474|LDLRAP1,ARH"	ko04144|Endocytosis	1512	XP_419992.1	XP_419992.1 low density lipoprotein receptor adapter protein 1 isoform X2 [Gallus gallus]	sp|Q8C142|ARH_MOUSE	sp|Q8C142|ARH_MOUSE Low density lipoprotein receptor adapter protein 1 OS=Mus musculus GN=Ldlrap1 PE=1 SV=3	9031.ENSGALP00000026582	similar to LDL receptor adaptor protein	_	KOG3536	_	PF00640.20|PID|Phosphotyrosine interaction domain (PTB/PID)|ENSGALT00000026633|m.13101:57-178;PF14719.3|PID_2|Phosphotyrosine interaction domain (PTB/PID)|ENSGALT00000026633|m.13101:57-187;PF08416.10|PTB|Phosphotyrosine-binding domain|ENSGALT00000026633|m.13101:60-164
ENSGALG00000016543	5.597180942	11.99857662	-1.098717628	2.08E-32	3.74E-31	down	yes	5.484441652	6.123385169	5.183716004	11.78708024	12.5157133	11.69293634	1	122350876	122496961	-	NHS	protein_coding	GO:0002088|lens development in camera-type eye; GO:0030154|cell differentiation	GO:0005794|Golgi apparatus; GO:0005923|bicellular tight junction; GO:0005925|focal adhesion; GO:0016324|apical plasma membrane; GO:0016604|nuclear body; GO:0030027|lamellipodium; GO:0030054|cell junction	--	--	--	4401	XP_015128470.1	XP_015128470.1 Nance-Horan syndrome protein isoform X1 [Gallus gallus]	sp|Q6T4R5|NHS_HUMAN	sp|Q6T4R5|NHS_HUMAN Nance-Horan syndrome protein OS=Homo sapiens GN=NHS PE=1 SV=2	9031.ENSGALP00000026643	Nance-Horan syndrome (congenital cataracts and dental anomalies)	_	_	NOG43400	PF15273.3|NHS|NHS-like|ENSGALT00000036628|m.3432:259-880
ENSGALG00000016554	0.202560337	0.87672331	-2.060611584	6.82E-08	2.47E-07	down	yes	0.254710389	0.236554913	0.116415708	0.887828689	0.718590798	1.023750444	1	123308765	123331190	+	ACE2	protein_coding	GO:0001817|regulation of cytokine production; GO:0002003|angiotensin maturation; GO:0003051|angiotensin-mediated drinking behavior; GO:0003081|regulation of systemic arterial blood pressure by renin-angiotensin; GO:0015827|tryptophan transport; GO:0019229|regulation of vasoconstriction; GO:0032800|receptor biosynthetic process; GO:0042127|regulation of cell population proliferation; GO:0046718|viral entry into host cell; GO:0046813|receptor-mediated virion attachment to host cell; GO:0050727|regulation of inflammatory response; GO:0060452|positive regulation of cardiac muscle contraction; GO:0097746|regulation of blood vessel diameter; GO:1903598|positive regulation of gap junction assembly; GO:1903779|regulation of cardiac conduction; GO:2000379|positive regulation of reactive oxygen species metabolic process	GO:0005576|extracellular region; GO:0005615|extracellular space; GO:0005737|cytoplasm; GO:0005886|plasma membrane; GO:0009986|cell surface; GO:0016021|integral component of membrane; GO:0045121|membrane raft; GO:0070062|extracellular exosome	GO:0001618|virus receptor activity; GO:0004175|endopeptidase activity; GO:0004180|carboxypeptidase activity; GO:0004181|metallocarboxypeptidase activity; GO:0008270|zinc ion binding	"ko:K09708|ACE2,ACEH"	ko04614|Renin-angiotensin system; ko04974|Protein digestion and absorption	3103	XP_416822.2	XP_416822.2 angiotensin-converting enzyme 2 [Gallus gallus]	sp|Q9BYF1|ACE2_HUMAN	sp|Q9BYF1|ACE2_HUMAN Angiotensin-converting enzyme 2 OS=Homo sapiens GN=ACE2 PE=1 SV=2	9031.ENSGALP00000026662	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	_	KOG3690	NOG43361	PF01401.15|Peptidase_M2|Angiotensin-converting enzyme|ENSGALT00000026713|m.3451:21-606;PF16959.2|Collectrin|Renal amino acid transporter|ENSGALT00000026713|m.3451:617-770
ENSGALG00000016591	0.276906927	0.591044732	-1.066889565	0.016763172	0.028273229	down	yes	0.354523728	0.341167451	0.135029602	0.59175597	0.595904565	0.585473662	3	105338705	105350819	+	DRC1	protein_coding	GO:0060285|cilium-dependent cell motility; GO:0070286|axonemal dynein complex assembly	GO:0005737|cytoplasm; GO:0005930|axoneme	--	ko:K19754|DRC1	--	2378	XP_420016.3	XP_420016.3 dynein regulatory complex protein 1 [Gallus gallus]	sp|Q95JM8|DRC1_MACFA	sp|Q95JM8|DRC1_MACFA Dynein regulatory complex protein 1 OS=Macaca fascicularis GN=DRC1 PE=2 SV=2	9031.ENSGALP00000026728	UPF0407 protein C2orf39 	_	_	NOG80321	PF14772.3|NYD-SP28|Sperm tail|ENSGALT00000026779|m.13217:114-213;PF14775.3|NYD-SP28_assoc|Sperm tail C-terminal domain|ENSGALT00000026779|m.13217:675-734
ENSGALG00000016592	17.64611151	47.15529436	-1.417558025	1.78E-63	9.71E-62	down	yes	14.90932539	19.25922289	18.76978625	46.84218388	46.77667656	47.84702264	1	124459466	124485720	+	PRPS2	protein_coding	GO:0006015|5-phosphoribose 1-diphosphate biosynthetic process; GO:0009116|nucleoside metabolic process; GO:0009156|ribonucleoside monophosphate biosynthetic process; GO:0009165|nucleotide biosynthetic process	GO:0070062|extracellular exosome	GO:0000287|magnesium ion binding; GO:0004749|ribose phosphate diphosphokinase activity; GO:0005524|ATP binding; GO:0016301|kinase activity; GO:0042803|protein homodimerization activity	"ko:K00948|PRPS,prsA"	ko00030|Pentose phosphate pathway; ko00230|Purine metabolism; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko01120|Microbial metabolism in diverse environments; ko01130|Biosynthesis of antibiotics; ko01200|Carbon metabolism; ko01230|Biosynthesis of amino acids	3368	NP_001006264.1	NP_001006264.1 ribose-phosphate pyrophosphokinase 2 [Gallus gallus]	sp|Q5ZI49|PRPS2_CHICK	sp|Q5ZI49|PRPS2_CHICK Ribose-phosphate pyrophosphokinase 2 OS=Gallus gallus GN=PRPS2 PE=2 SV=1	9031.ENSGALP00000026730	Ribose-phosphate pyrophosphokinase 2 (EC 2.7.6.1)(Phosphoribosyl pyrophosphate synthetase II [...] 	COG0462	KOG1448	_	PF14572.3|Pribosyl_synth|Phosphoribosyl synthetase-associated domain|ENSGALT00000026780|m.3490:362-470;PF13793.3|Pribosyltran_N|N-terminal domain of ribose phosphate pyrophosphokinase|ENSGALT00000026780|m.3490:154-277;PF00156.24|Pribosyltran|Phosphoribosyl transferase domain|ENSGALT00000026780|m.3490:308-404
ENSGALG00000016602	7.044203314	15.01237599	-1.09055795	7.60E-34	1.45E-32	down	yes	6.754384215	7.264245445	7.113980283	14.73835893	15.42831833	14.87045071	1	125571190	125724317	+	ARHGAP6	protein_coding	GO:0007015|actin filament organization; GO:0007165|signal transduction; GO:0007202|activation of phospholipase C activity; GO:0010518|positive regulation of phospholipase activity; GO:0043087|regulation of GTPase activity; GO:0043547|positive regulation of GTPase activity; GO:0048041|focal adhesion assembly; GO:0051497|negative regulation of stress fiber assembly; GO:0051895|negative regulation of focal adhesion assembly	GO:0005737|cytoplasm; GO:0015629|actin cytoskeleton	GO:0005096|GTPase activator activity; GO:0016004|phospholipase activator activity; GO:0017124|SH3 domain binding; GO:0043274|phospholipase binding	ko:K20631|ARHGAP6	--	2510	XP_416840.4	XP_416840.4 LOW QUALITY PROTEIN: rho GTPase-activating protein 6 [Gallus gallus]	sp|O54834|RHG06_MOUSE	sp|O54834|RHG06_MOUSE Rho GTPase-activating protein 6 OS=Mus musculus GN=Arhgap6 PE=1 SV=3	9031.ENSGALP00000026744	Rho GTPase activating protein 6	_	KOG2710	_	PF00620.24|RhoGAP|RhoGAP domain|ENSGALT00000102910|m.3507:130-287
ENSGALG00000016608	1.597385179	0.773262957	1.037147049	1.33E-06	4.19E-06	up	yes	1.448070711	1.541216182	1.802868643	0.778964088	0.775925171	0.764899613	3	105444375	105456601	+	ADCY3	protein_coding	GO:0003091|renal water homeostasis; GO:0006171|cAMP biosynthetic process; GO:0006182|cGMP biosynthetic process; GO:0007165|signal transduction; GO:0007189|adenylate cyclase-activating G protein-coupled receptor signaling pathway; GO:0007190|activation of adenylate cyclase activity; GO:0007193|adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; GO:0007338|single fertilization; GO:0007340|acrosome reaction; GO:0007608|sensory perception of smell; GO:0008355|olfactory learning; GO:0030317|flagellated sperm motility; GO:0034199|activation of protein kinase A activity; GO:0071377|cellular response to glucagon stimulus; GO:1904322|cellular response to forskolin	"GO:0005737|cytoplasm; GO:0005794|Golgi apparatus; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0005929|cilium; GO:0008074|guanylate cyclase complex, soluble; GO:0016020|membrane; GO:0016021|integral component of membrane"	GO:0004016|adenylate cyclase activity; GO:0004383|guanylate cyclase activity; GO:0005516|calmodulin binding; GO:0005524|ATP binding; GO:0046872|metal ion binding	ko:K08043|ADCY3	ko00230|Purine metabolism; ko01522|Endocrine resistance; ko04015|Rap1 signaling pathway; ko04020|Calcium signaling pathway; ko04022|cGMP-PKG signaling pathway; ko04024|cAMP signaling pathway; ko04062|Chemokine signaling pathway; ko04072|Phospholipase D signaling pathway; ko04114|Oocyte meiosis; ko04211|Longevity regulating pathway; ko04213|Longevity regulating pathway - multiple species; ko04261|Adrenergic signaling in cardiomyocytes; ko04270|Vascular smooth muscle contraction; ko04371|Apelin signaling pathway; ko04540|Gap junction; ko04611|Platelet activation; ko04713|Circadian entrainment; ko04723|Retrograde endocannabinoid signaling; ko04724|Glutamatergic synapse; ko04725|Cholinergic synapse; ko04727|GABAergic synapse; ko04740|Olfactory transduction; ko04750|Inflammatory mediator regulation of TRP channels; ko04911|Insulin secretion; ko04912|GnRH signaling pathway; ko04913|Ovarian steroidogenesis; ko04914|Progesterone-mediated oocyte maturation; ko04915|Estrogen signaling pathway; ko04916|Melanogenesis; ko04918|Thyroid hormone synthesis; ko04921|Oxytocin signaling pathway; ko04923|Regulation of lipolysis in adipocytes; ko04925|Aldosterone synthesis and secretion; ko04962|Vasopressin-regulated water reabsorption; ko04970|Salivary secretion; ko04971|Gastric acid secretion; ko04972|Pancreatic secretion; ko04976|Bile secretion; ko05032|Morphine addiction; ko05110|Vibrio cholerae infection; ko05166|HTLV-I infection; ko05200|Pathways in cancer; ko05414|Dilated cardiomyopathy	3384	XP_015140679.1	XP_015140679.1 adenylate cyclase type 3 isoform X2 [Gallus gallus]	sp|O60266|ADCY3_HUMAN	sp|O60266|ADCY3_HUMAN Adenylate cyclase type 3 OS=Homo sapiens GN=ADCY3 PE=1 SV=3	9031.ENSGALP00000026753	annotation not avaliable	COG2114	KOG3619	_	PF00211.17|Guanylate_cyc|Adenylate and Guanylate cyclase catalytic domain|ENSGALT00000026804|m.13238:310-471;PF00211.17|Guanylate_cyc|Adenylate and Guanylate cyclase catalytic domain|ENSGALT00000026804|m.13238:899-1104;PF16214.2|AC_N|Adenylyl cyclase N-terminal extracellular and transmembrane region|ENSGALT00000026804|m.13238:38-297
ENSGALG00000016618	1.077285632	2.656213617	-1.294061385	2.96E-07	1.00E-06	down	yes	1.313257053	1.061134397	0.857465447	2.631195656	3.063331374	2.274113821	1	127493302	127513076	+	PNPLA4	protein_coding	GO:0019433|triglyceride catabolic process; GO:0055088|lipid homeostasis	GO:0005739|mitochondrion; GO:0005811|lipid droplet; GO:0005829|cytosol; GO:0016020|membrane	GO:0004806|triglyceride lipase activity; GO:0050253|retinyl-palmitate esterase activity	ko:K11157|PNPLA4	ko00830|Retinol metabolism	1966	XP_015129463.2	XP_015129463.2 patatin-like phospholipase domain-containing protein 4 isoform X1 [Gallus gallus]	sp|P41247|PLPL4_HUMAN	sp|P41247|PLPL4_HUMAN Patatin-like phospholipase domain-containing protein 4 OS=Homo sapiens GN=PNPLA4 PE=2 SV=3	9031.ENSGALP00000026775	PNPLA4 	_	KOG3773	_	PF01734.19|Patatin|Patatin-like phospholipase|ENSGALT00000026826|m.3528:103-272
ENSGALG00000016646	5.114750322	2.526762987	1.014492985	1.55E-06	4.85E-06	up	yes	5.710803899	4.841411126	4.792035942	2.248801128	2.840897915	2.490589917	3	106942888	106966214	-	ENSGALG00000016646	protein_coding	--	GO:0016021|integral component of membrane	--	--	--	1143	XP_002186951.2	XP_002186951.2 PREDICTED: XK-related protein 6 [Taeniopygia guttata]	sp|E9Q6C8|XKR6_MOUSE	sp|E9Q6C8|XKR6_MOUSE XK-related protein 6 OS=Mus musculus GN=Xkr6 PE=2 SV=1	9031.ENSGALP00000026821	"XK, Kell blood group complex subunit-related family, member 6"	_	KOG4790	_	PF09815.6|XK-related|XK-related protein|ENSGALT00000026872|m.13280:2-250
ENSGALG00000016651	4.460253289	18.29100524	-2.033494412	2.28E-47	7.54E-46	down	yes	3.354863351	5.043600407	4.982296111	16.41563945	19.99174197	18.46563431	3	107177930	107186837	+	ENSGALG00000016651	protein_coding	GO:0006567|threonine catabolic process; GO:0019518|L-threonine catabolic process to glycine	GO:0005739|mitochondrion	GO:0008743|L-threonine 3-dehydrogenase activity; GO:0042802|identical protein binding; GO:0050662|coenzyme binding	ko:K15789|TDH	"ko00260|Glycine, serine and threonine metabolism"	1869	XP_420039.1	"XP_420039.1 L-threonine 3-dehydrogenase, mitochondrial [Gallus gallus]"	sp|Q2KIR8|TDH_BOVIN	"sp|Q2KIR8|TDH_BOVIN L-threonine 3-dehydrogenase, mitochondrial OS=Bos taurus GN=TDH PE=2 SV=1"	9031.ENSGALP00000026827	L-threonine dehydrogenase	COG0451	KOG2774	_	"PF01370.18|Epimerase|NAD dependent epimerase/dehydratase family|ENSGALT00000026878|m.13289:58-293;PF16363.2|GDP_Man_Dehyd|GDP-mannose 4,6 dehydratase|ENSGALT00000026878|m.13289:59-359;PF04321.14|RmlD_sub_bind|RmlD substrate binding domain|ENSGALT00000026878|m.13289:57-203;PF07993.9|NAD_binding_4|Male sterility protein|ENSGALT00000026878|m.13289:119-274;PF01073.16|3Beta_HSD|3-beta hydroxysteroid dehydrogenase/isomerase family|ENSGALT00000026878|m.13289:59-180"
ENSGALG00000016665	59.96192147	21.4352605	1.483628356	3.71E-67	2.22E-65	up	yes	59.35062928	62.78072202	57.7544131	20.01701929	24.57437418	19.71438802	3	107359160	107370240	+	FDFT1	protein_coding	GO:0006694|steroid biosynthetic process; GO:0006695|cholesterol biosynthetic process; GO:0006696|ergosterol biosynthetic process; GO:0008299|isoprenoid biosynthetic process; GO:0019216|regulation of lipid metabolic process; GO:0045338|farnesyl diphosphate metabolic process; GO:0045540|regulation of cholesterol biosynthetic process	GO:0005783|endoplasmic reticulum; GO:0005789|endoplasmic reticulum membrane; GO:0016021|integral component of membrane	GO:0004310|farnesyl-diphosphate farnesyltransferase activity; GO:0016491|oxidoreductase activity; GO:0051996|squalene synthase activity	ko:K00801|FDFT1	ko00100|Steroid biosynthesis; ko00909|Sesquiterpenoid and triterpenoid biosynthesis; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko01130|Biosynthesis of antibiotics	2611	NP_001034383.1	NP_001034383.1 squalene synthase [Gallus gallus]	sp|P37268|FDFT_HUMAN	sp|P37268|FDFT_HUMAN Squalene synthase OS=Homo sapiens GN=FDFT1 PE=1 SV=1	9031.ENSGALP00000026843	farnesyl-diphosphate farnesyltransferase 1 	COG1562	KOG1459	_	PF00494.16|SQS_PSY|Squalene/phytoene synthase|ENSGALT00000026894|m.13298:49-320
ENSGALG00000016673	13.08471757	6.361439641	1.039293649	7.76E-20	7.24E-19	up	yes	13.4046484	11.81986638	14.02963793	6.520717224	5.668314089	6.895287608	3	107485825	107498655	+	TRAM2	protein_coding	GO:0015031|protein transport; GO:0032964|collagen biosynthetic process; GO:0045048|protein insertion into ER membrane	GO:0016021|integral component of membrane	--	--	--	2386	XP_015140661.1	XP_015140661.1 translocating chain-associated membrane protein 2 isoform X1 [Gallus gallus]	sp|Q15035|TRAM2_HUMAN	sp|Q15035|TRAM2_HUMAN Translocating chain-associated membrane protein 2 OS=Homo sapiens GN=TRAM2 PE=1 SV=1	9031.ENSGALP00000026854	translocation associated membrane protein 2	_	KOG1608	_	PF03798.13|TRAM_LAG1_CLN8|TLC domain|ENSGALT00000026905|m.13308:244-445;PF08390.8|TRAM1|TRAM1-like protein|ENSGALT00000026905|m.13308:180-241
ENSGALG00000016675	4.212127146	1.727628536	1.280850324	1.98E-17	1.57E-16	up	yes	3.887047557	4.486090089	4.263243792	1.753173274	1.715242859	1.714469475	3	107527254	107530181	-	PAQR8	protein_coding	GO:0007275|multicellular organism development; GO:0048477|oogenesis; GO:0048545|response to steroid hormone	GO:0005794|Golgi apparatus; GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0003707|steroid hormone receptor activity; GO:0005496|steroid binding	--	--	2928	XP_025004570.1	XP_025004570.1 membrane progestin receptor beta isoform X2 [Gallus gallus]	sp|Q8TEZ7|PAQR8_HUMAN	sp|Q8TEZ7|PAQR8_HUMAN Membrane progestin receptor beta OS=Homo sapiens GN=PAQR8 PE=2 SV=1	9031.ENSGALP00000026856	progestin and adipoQ receptor family member VIII 	COG1272	KOG0748	_	PF03006.17|HlyIII|Haemolysin-III related|ENSGALT00000026907|m.13311:79-304
ENSGALG00000016687	0.564539253	0.244571521	1.174334428	0.003270435	0.006315592	up	yes	0.594707552	0.69766415	0.401246058	0.274829178	0.168003331	0.290882055	1	130386938	130414561	+	P2RY8	protein_coding	GO:0007596|blood coagulation; GO:0035025|positive regulation of Rho protein signal transduction; GO:0051482|positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	GO:0005887|integral component of plasma membrane	GO:0004930|G protein-coupled receptor activity; GO:0015057|thrombin-activated receptor activity; GO:0045028|G protein-coupled purinergic nucleotide receptor activity	ko:K08386|P2RY8	ko04080|Neuroactive ligand-receptor interaction	3101	NP_001008679.1	NP_001008679.1 P2Y purinoceptor 8 [Gallus gallus]	sp|Q5ZI82|P2RY8_CHICK	sp|Q5ZI82|P2RY8_CHICK P2Y purinoceptor 8 OS=Gallus gallus GN=P2RY8 PE=2 SV=1	9031.ENSGALP00000026875	P2Y purinoceptor 8 (P2Y8); Probable receptor for purines coupled to G-proteins	_	KOG3656	_	PF00001.18|7tm_1|7 transmembrane receptor (rhodopsin family)|ENSGALT00000099472|m.3569:39-292
ENSGALG00000016690	0.195999784	1.10637295	-2.438104345	7.00E-07	2.28E-06	down	yes	0.121744661	0.410611138	0.055643553	1.236438905	1.049660589	1.033019356	3	108774929	108782996	+	CYP2AC1	protein_coding	--	GO:0005789|endoplasmic reticulum membrane; GO:0031090|organelle membrane	GO:0005506|iron ion binding; GO:0020037|heme binding; GO:0070330|aromatase activity	ko:K17854|CYP2K	--	2160	NP_001316427.1	NP_001316427.1 cytochrome P450 2AC1 [Gallus gallus]	sp|O93297|CP2K4_ONCMY	sp|O93297|CP2K4_ONCMY Cytochrome P450 2K4 OS=Oncorhynchus mykiss GN=cyp2k4 PE=2 SV=1	9031.ENSGALP00000026886	similar to LOC494798 protein	COG2124	KOG0156	_	PF00067.19|p450|Cytochrome P450|ENSGALT00000026937|m.13337:34-489
ENSGALG00000016713	7.067644121	18.72745282	-1.404583719	4.50E-39	1.07E-37	down	yes	8.006205904	5.971366728	7.22535973	19.03339883	17.78189506	19.36706457	3	109831301	109844348	-	PLA2G7	protein_coding	GO:0016042|lipid catabolic process	GO:0005615|extracellular space	GO:0003847|1-alkyl-2-acetylglycerophosphocholine esterase activity	"ko:K01062|PLA2G7,PAFAH"	ko00565|Ether lipid metabolism; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko01130|Biosynthesis of antibiotics	2672	XP_015140576.1	XP_015140576.1 platelet-activating factor acetylhydrolase isoform X1 [Gallus gallus]	sp|Q90678|PAFA_CHICK	sp|Q90678|PAFA_CHICK Platelet-activating factor acetylhydrolase OS=Gallus gallus GN=PLA2G7 PE=2 SV=1	9031.ENSGALP00000026919	Platelet-activating factor acetylhydrolase Precursor (PAF acetylhydrolase)(EC 3.1.1.47)(PAF  [...] 	COG4188	KOG3847	_	"PF03403.10|PAF-AH_p_II|Platelet-activating factor acetylhydrolase, isoform II|ENSGALT00000026970|m.13374:32-410;PF12740.4|Chlorophyllase2|Chlorophyllase enzyme|ENSGALT00000026970|m.13374:127-323"
ENSGALG00000016721	0.507575795	1.237576312	-1.269286011	0.000437182	0.000973548	down	yes	0.212932395	0.823189873	0.486605116	1.33247515	1.14837251	1.231881275	1	131370527	131395496	-	PLCXD1	protein_coding	GO:0006629|lipid metabolic process	GO:0005737|cytoplasm	GO:0008081|phosphoric diester hydrolase activity	--	--	2634	NP_001122109.1	NP_001122109.1 PI-PLC X domain-containing protein 1 [Gallus gallus]	sp|Q9NUJ7|PLCX1_HUMAN	sp|Q9NUJ7|PLCX1_HUMAN PI-PLC X domain-containing protein 1 OS=Homo sapiens GN=PLCXD1 PE=2 SV=1	9031.ENSGALP00000026933	Putative uncharacterized protein 	_	KOG4306	_	_
ENSGALG00000016723	0.405420691	0.132977418	1.538785776	0.007247938	0.01316351	up	yes	0.270064929	0.448132061	0.498065084	0.016039647	0.213619385	0.16927322	3	110067035	110073729	+	ADGRF2	protein_coding	GO:0007166|cell surface receptor signaling pathway; GO:0007186|G protein-coupled receptor signaling pathway	GO:0016021|integral component of membrane	GO:0004930|G protein-coupled receptor activity	ko:K08457|GPR115	--	3294	XP_015140646.1	XP_015140646.1 adhesion G protein-coupled receptor F4 isoform X1 [Gallus gallus]	sp|Q8IZF3|AGRF4_HUMAN	sp|Q8IZF3|AGRF4_HUMAN Adhesion G protein-coupled receptor F4 OS=Homo sapiens GN=ADGRF4 PE=2 SV=3	_	_	_	_	_	"PF00002.21|7tm_2|7 transmembrane receptor (Secretin family)|ENSGALT00000096569|m.13394:389-634;PF01825.18|GPS|GPCR proteolysis site, GPS, motif|ENSGALT00000096569|m.13394:336-379"
ENSGALG00000016735	4.450859899	11.81581044	-1.406545313	1.26E-41	3.41E-40	down	yes	4.720276734	4.000578479	4.631724483	11.73651155	12.18832993	11.52258984	1	131653636	131675363	+	TUBGCP5	protein_coding	GO:0007020|microtubule nucleation; GO:0031122|cytoplasmic microtubule organization; GO:0051298|centrosome duplication; GO:0051321|meiotic cell cycle; GO:0051415|microtubule nucleation by interphase microtubule organizing center; GO:0090307|mitotic spindle assembly	GO:0000922|spindle pole; GO:0000923|equatorial microtubule organizing center; GO:0005813|centrosome; GO:0005829|cytosol; GO:0005874|microtubule; GO:0008274|gamma-tubulin ring complex	GO:0005200|structural constituent of cytoskeleton; GO:0008017|microtubule binding; GO:0043015|gamma-tubulin binding	"ko:K16572|TUBGCP5,GCP5"	--	3246	XP_004938518.1	XP_004938518.1 gamma-tubulin complex component 5 isoform X1 [Gallus gallus]	sp|Q96RT8|GCP5_HUMAN	sp|Q96RT8|GCP5_HUMAN Gamma-tubulin complex component 5 OS=Homo sapiens GN=TUBGCP5 PE=1 SV=1	9031.ENSGALP00000026956	annotation not avaliable	_	KOG4344	_	PF04130.10|Spc97_Spc98|Spc97 / Spc98 family|ENSGALT00000066931|m.3602:323-987
ENSGALG00000016764	95.29851592	217.8172786	-1.192507604	2.49E-115	4.78E-113	down	yes	93.64929652	96.90939487	95.33685638	209.7345928	220.7013086	223.0159346	1	133860171	133890836	+	EIF5B	protein_coding	GO:0006446|regulation of translational initiation	GO:0005737|cytoplasm; GO:0005829|cytosol	GO:0003723|RNA binding; GO:0003743|translation initiation factor activity; GO:0003924|GTPase activity; GO:0005525|GTP binding; GO:0046872|metal ion binding	ko:K03243|EIF5B	ko03013|RNA transport	4437	NP_001033585.1	NP_001033585.1 eukaryotic translation initiation factor 5B [Gallus gallus]	sp|O60841|IF2P_HUMAN	sp|O60841|IF2P_HUMAN Eukaryotic translation initiation factor 5B OS=Homo sapiens GN=EIF5B PE=1 SV=4	9031.ENSGALP00000027015	eukaryotic translation initiation factor 5B 	COG0532	KOG1144	_	PF00009.24|GTP_EFTU|Elongation factor Tu GTP binding domain|ENSGALT00000027066|m.3652:633-843;PF11987.5|IF-2|Translation-initiation factor 2|ENSGALT00000027066|m.3652:975-1069;PF03144.22|GTP_EFTU_D2|Elongation factor Tu domain 2|ENSGALT00000027066|m.3652:870-946;PF01926.20|MMR_HSR1|50S ribosome-binding GTPase|ENSGALT00000027066|m.3652:634-757
ENSGALG00000016774	1.882889891	4.728363787	-1.323798474	1.04E-20	1.02E-19	down	yes	2.219437451	1.717698659	1.711533562	4.632832105	4.708582088	4.843677167	1	134540472	134668511	+	NPAS2	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0032922|circadian regulation of gene expression; GO:0045739|positive regulation of DNA repair; GO:0045893|positive regulation of transcription, DNA-templated; GO:0051775|response to redox state; GO:0060548|negative regulation of cell death; GO:2001020|regulation of response to DNA damage stimulus"	GO:0005634|nucleus; GO:0005667|transcription factor complex; GO:0005737|cytoplasm	GO:0001047|core promoter binding; GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity; GO:0046872|metal ion binding; GO:0046983|protein dimerization activity	ko:K09026|NPAS2	ko04710|Circadian rhythm	3731	XP_015133164.1	XP_015133164.1 neuronal PAS domain-containing protein 2 isoform X2 [Gallus gallus]	sp|Q5ZQU2|NPAS2_CHICK	sp|Q5ZQU2|NPAS2_CHICK Neuronal PAS domain-containing protein 2 OS=Gallus gallus GN=NPAS2 PE=1 SV=1	9031.ENSGALP00000035797	Neuronal PAS domain-containing protein 2 (Neuronal PAS2)(Member of PAS protein 4)(MOP4); BMA [...] 	_	KOG3561	_	PF14598.3|PAS_11|PAS domain|ENSGALT00000036585|m.3680:325-428;PF08447.9|PAS_3|PAS fold|ENSGALT00000036585|m.3680:338-424;PF00989.22|PAS|PAS fold|ENSGALT00000036585|m.3680:161-231;PF00010.23|HLH|Helix-loop-helix DNA-binding domain|ENSGALT00000036585|m.3680:86-133
ENSGALG00000016796	7.317265358	3.168845715	1.204771867	9.09E-30	1.41E-28	up	yes	7.143695734	7.243716055	7.564384285	2.963419974	3.441462615	3.101654557	1	136427099	136441778	+	C1H2ORF49	protein_coding	GO:0009952|anterior/posterior pattern specification; GO:0042981|regulation of apoptotic process; GO:0048598|embryonic morphogenesis; GO:0060027|convergent extension involved in gastrulation; GO:0060062|Spemann organizer formation at the dorsal lip of the blastopore	GO:0072669|tRNA-splicing ligase complex	--	ko:K15432|ASW	--	4160	NP_001025984.1	NP_001025984.1 ashwin [Gallus gallus]	sp|Q5ZK74|ASHWN_CHICK	sp|Q5ZK74|ASHWN_CHICK Ashwin OS=Gallus gallus GN=RCJMB04_12m8 PE=2 SV=1	9031.ENSGALP00000027066	Ashwin 	_	_	NOG42951	PF15323.3|Ashwin|Developmental protein|ENSGALT00000027117|m.3735:32-249
ENSGALG00000016803	2.055447018	4.505404268	-1.128401106	1.18E-14	7.64E-14	down	yes	2.17406378	1.958015516	2.034261756	4.430124919	4.664770222	4.421317662	1	136952979	137035946	-	ST6GAL2	protein_coding	GO:0009311|oligosaccharide metabolic process; GO:0018279|protein N-linked glycosylation via asparagine	GO:0000139|Golgi membrane; GO:0016021|integral component of membrane; GO:0032580|Golgi cisterna membrane	"GO:0003835|beta-galactoside alpha-2,6-sialyltransferase activity"	"ko:K00779|SIAT2,ST6GAL2"	ko00510|N-Glycan biosynthesis; ko00514|Other types of O-glycan biosynthesis; ko01100|Metabolic pathways	2501	XP_015133314.1	"XP_015133314.1 beta-galactoside alpha-2,6-sialyltransferase 2 isoform X1 [Gallus gallus]"	sp|Q701R0|SIAT2_CHICK	"sp|Q701R0|SIAT2_CHICK Beta-galactoside alpha-2,6-sialyltransferase 2 OS=Gallus gallus GN=ST6GAL2 PE=2 SV=1"	9031.ENSGALP00000027075	"Beta-galactoside alpha-2,6-sialyltransferase 2 (EC 2.4.99.1)(CMP-N-acetylneuraminate-beta-ga [...] "	_	KOG2692	_	PF00777.15|Glyco_transf_29|Glycosyltransferase family 29 (sialyltransferase)|ENSGALT00000036571|m.3753:318-528
ENSGALG00000016832	0.088876872	0.574473071	-2.56343154	1.33E-05	3.67E-05	down	yes	0.152580374	0.055936031	0.058114212	0.583493784	0.553162318	0.586763111	1	138904758	138912133	-	PROZ	protein_coding	GO:0007596|blood coagulation; GO:0030195|negative regulation of blood coagulation	GO:0005576|extracellular region; GO:0005615|extracellular space; GO:0070062|extracellular exosome	GO:0004252|serine-type endopeptidase activity; GO:0005509|calcium ion binding	--	--	1796	XP_416945.3	XP_416945.3 vitamin K-dependent protein Z [Gallus gallus]	sp|Q9CQW3|PROZ_MOUSE	sp|Q9CQW3|PROZ_MOUSE Vitamin K-dependent protein Z OS=Mus musculus GN=Proz PE=1 SV=1	9031.ENSGALP00000027123	"protein Z, vitamin K-dependent plasma glycoprotein"	_	KOG3627	_	PF00089.23|Trypsin|Trypsin|ENSGALT00000093588|m.3844:5-130
ENSGALG00000016844	5.807107957	16.67602903	-1.520266677	2.85E-25	3.62E-24	down	yes	4.76959094	6.072611706	6.579121226	19.43175003	16.27619146	14.32014561	1	140394688	140425482	-	RAB20	protein_coding	GO:0015031|protein transport; GO:0030100|regulation of endocytosis; GO:0090383|phagosome acidification; GO:0090385|phagosome-lysosome fusion	GO:0005769|early endosome; GO:0005794|Golgi apparatus; GO:0005886|plasma membrane; GO:0030670|phagocytic vesicle membrane; GO:0043231|intracellular membrane-bounded organelle; GO:0045335|phagocytic vesicle	GO:0003924|GTPase activity; GO:0005525|GTP binding	ko:K07911|RAB20	--	1635	XP_416953.2	XP_416953.2 ras-related protein Rab-20 [Gallus gallus]	sp|Q9NX57|RAB20_HUMAN	sp|Q9NX57|RAB20_HUMAN Ras-related protein Rab-20 OS=Homo sapiens GN=RAB20 PE=1 SV=1	9031.ENSGALP00000027160	"RAB20, member RAS oncogene family"	COG1100	KOG0092	_	PF00071.19|Ras|Ras family|ENSGALT00000027211|m.3863:1-128
ENSGALG00000016853	13.40893346	4.423006795	1.597912531	4.79E-55	2.00E-53	up	yes	12.56869544	13.6159002	14.04220474	4.544448142	4.554706988	4.169865257	1	141647287	141655299	-	ABHD13	protein_coding	--	GO:0016021|integral component of membrane	GO:0016787|hydrolase activity	ko:K06889|K06889	--	2668	XP_025928812.1	XP_025928812.1 protein ABHD13 [Apteryx rowi]	sp|Q5ZJL8|ABHDD_CHICK	sp|Q5ZJL8|ABHDD_CHICK Protein ABHD13 OS=Gallus gallus GN=ABHD13 PE=2 SV=1	_	_	_	_	_	"PF00561.17|Abhydrolase_1|alpha/beta hydrolase fold|ENSGALT00000027229|m.3910:174-281;PF12146.5|Hydrolase_4|Serine aminopeptidase, S33|ENSGALT00000027229|m.3910:175-284"
ENSGALG00000016855	19.23759049	7.516841192	1.354561416	1.56E-65	8.99E-64	up	yes	18.94827168	19.07390559	19.69059421	7.625339412	7.45470247	7.470481696	1	142495383	142506971	+	ARGLU1	protein_coding	--	--	--	--	--	3184	PNI56176.1	"PNI56176.1 ARGLU1 isoform 4, partial [Pan troglodytes]"	_	_	_	_	_	_	_	PF15346.3|ARGLU|Arginine and glutamate-rich 1|ENSGALT00000027231|m.3919:122-272
ENSGALG00000016889	43.58519796	20.96710363	1.055353735	1.18E-43	3.43E-42	up	yes	45.49285289	43.45030144	41.81243955	19.8196577	21.2221674	21.8594858	1	146713664	146744321	-	RAP2A	protein_coding	GO:0001934|positive regulation of protein phosphorylation; GO:0030033|microvillus assembly; GO:0030336|negative regulation of cell migration; GO:0031532|actin cytoskeleton reorganization; GO:0031954|positive regulation of protein autophosphorylation; GO:0032486|Rap protein signal transduction; GO:0034613|cellular protein localization; GO:0035690|cellular response to drug; GO:0045184|establishment of protein localization; GO:0046328|regulation of JNK cascade; GO:0048814|regulation of dendrite morphogenesis; GO:0072659|protein localization to plasma membrane	GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0016020|membrane; GO:0030496|midbody; GO:0055037|recycling endosome; GO:0055038|recycling endosome membrane; GO:0070062|extracellular exosome	GO:0000287|magnesium ion binding; GO:0003924|GTPase activity; GO:0005525|GTP binding; GO:0019003|GDP binding	ko:K07837|RAP2A	--	2013	XP_001233104.2	XP_001233104.2 ras-related protein Rap-2a [Gallus gallus]	sp|Q80ZJ1|RAP2A_MOUSE	sp|Q80ZJ1|RAP2A_MOUSE Ras-related protein Rap-2a OS=Mus musculus GN=Rap2a PE=1 SV=2	9031.ENSGALP00000027241	"RAP2A, member of RAS oncogene family"	COG1100	KOG0395	_	"PF00071.19|Ras|Ras family|ENSGALT00000027292|m.3994:5-164;PF08477.10|Roc|Ras of Complex, Roc, domain of DAPkinase|ENSGALT00000027292|m.3994:5-120;PF00025.18|Arf|ADP-ribosylation factor family|ENSGALT00000027292|m.3994:2-126"
ENSGALG00000016912	8.345202848	2.71152009	1.618262169	1.45E-37	3.28E-36	up	yes	7.752075746	8.089607637	9.19392516	2.850970427	2.769950328	2.513639514	1	155290926	155305744	+	EDNRB	protein_coding	GO:0008217|regulation of blood pressure; GO:0042310|vasoconstriction; GO:0048484|enteric nervous system development	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0004962|endothelin receptor activity	ko:K04198|EDNRB	ko04020|Calcium signaling pathway; ko04022|cGMP-PKG signaling pathway; ko04080|Neuroactive ligand-receptor interaction; ko04916|Melanogenesis; ko05200|Pathways in cancer	2746	XP_021272636.1	XP_021272636.1 endothelin B receptor [Numida meleagris]	sp|Q90328|EDNRB_COTJA	sp|Q90328|EDNRB_COTJA Endothelin receptor type B (Fragment) OS=Coturnix japonica GN=EDNRB PE=2 SV=1	9031.ENSGALP00000035729	Endothelin receptor type B Fragment 	_	KOG3656	_	PF00001.18|7tm_1|7 transmembrane receptor (rhodopsin family)|ENSGALT00000036512|m.4063:237-503;PF10320.6|7TM_GPCR_Srsx|Serpentine type 7TM GPCR chemoreceptor Srsx|ENSGALT00000036512|m.4063:231-519;PF10328.6|7TM_GPCR_Srx|Serpentine type 7TM GPCR chemoreceptor Srx|ENSGALT00000036512|m.4063:230-438
ENSGALG00000016975	4.888050982	2.260276878	1.109339535	0.000119586	0.000289686	up	yes	5.662325993	4.209283758	4.792543196	2.381317082	1.150817801	3.24869575	1	169017605	169018944	-	KCTD4	protein_coding	GO:0051260|protein homooligomerization	--	--	--	--	1340	NP_001186255.1	NP_001186255.1 BTB/POZ domain-containing protein KCTD4 [Gallus gallus]	sp|Q8WVF5|KCTD4_HUMAN	sp|Q8WVF5|KCTD4_HUMAN BTB/POZ domain-containing protein KCTD4 OS=Homo sapiens GN=KCTD4 PE=1 SV=2	9031.ENSGALP00000027376	potassium channel tetramerisation domain containing 4	_	KOG2723	_	PF02214.19|BTB_2|BTB/POZ domain|ENSGALT00000027428|m.4230:33-120
ENSGALG00000016979	3.921546504	14.4113445	-1.875036848	1.37E-50	5.04E-49	down	yes	4.071112692	4.315809828	3.377716991	14.6404066	14.71661224	13.87701465	1	169101305	169110752	+	SLC25A30	protein_coding	GO:0006839|mitochondrial transport	GO:0005743|mitochondrial inner membrane; GO:0016021|integral component of membrane	GO:0022857|transmembrane transporter activity	ko:K15106|SLC25A14_30	--	2032	XP_417040.3	XP_417040.3 kidney mitochondrial carrier protein 1 isoform X1 [Gallus gallus]	sp|Q5XGI1|KMCP1_XENTR	sp|Q5XGI1|KMCP1_XENTR Kidney mitochondrial carrier protein 1 OS=Xenopus tropicalis GN=slc25a30 PE=2 SV=1	9031.ENSGALP00000027380	"solute carrier family 25, member 30"	_	KOG0753	_	PF00153.24|Mito_carr|Mitochondrial carrier protein|ENSGALT00000027432|m.4232:6-99;PF00153.24|Mito_carr|Mitochondrial carrier protein|ENSGALT00000027432|m.4232:105-190;PF00153.24|Mito_carr|Mitochondrial carrier protein|ENSGALT00000027432|m.4232:199-289
ENSGALG00000016988	0.956044056	2.096568878	-1.124734198	4.98E-06	1.46E-05	down	yes	0.76907606	0.770187443	1.328868666	1.926225188	2.136586098	2.226895348	1	169433594	169458314	-	RUBCNL	protein_coding	--	--	--	--	--	2809	XP_025002572.1	XP_025002572.1 protein RUBCNL-like isoform X2 [Gallus gallus]	sp|Q9H714|RUBCL_HUMAN	sp|Q9H714|RUBCL_HUMAN Protein RUBCNL-like OS=Homo sapiens GN=RUBCNL PE=1 SV=3	9031.ENSGALP00000027394	chromosome 13 open reading frame 18	_	KOG1829	_	PF13901.3|zf-RING_9|Putative zinc-RING and/or ribbon|ENSGALT00000027446|m.4249:551-748
ENSGALG00000017034	9.326084884	22.65916222	-1.279841492	1.29E-59	6.29E-58	down	yes	8.886101968	9.604331157	9.487821528	24.76765186	21.1083538	22.10148101	1	171900251	171963536	+	FOXO1	protein_coding	"GO:0001568|blood vessel development; GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated; GO:0006357|regulation of transcription by RNA polymerase II; GO:0006914|autophagy; GO:0006915|apoptotic process; GO:0006974|cellular response to DNA damage stimulus; GO:0008286|insulin receptor signaling pathway; GO:0009267|cellular response to starvation; GO:0010508|positive regulation of autophagy; GO:0030154|cell differentiation; GO:0032868|response to insulin; GO:0032869|cellular response to insulin stimulus; GO:0032873|negative regulation of stress-activated MAPK cascade; GO:0034599|cellular response to oxidative stress; GO:0035947|regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter; GO:0042127|regulation of cell population proliferation; GO:0042593|glucose homeostasis; GO:0043065|positive regulation of apoptotic process; GO:0043066|negative regulation of apoptotic process; GO:0045599|negative regulation of fat cell differentiation; GO:0045722|positive regulation of gluconeogenesis; GO:0045732|positive regulation of protein catabolic process; GO:0045893|positive regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0070166|enamel mineralization; GO:0070301|cellular response to hydrogen peroxide; GO:0071455|cellular response to hyperoxia; GO:0071549|cellular response to dexamethasone stimulus; GO:0071732|cellular response to nitric oxide; GO:0090090|negative regulation of canonical Wnt signaling pathway; GO:0097150|neuronal stem cell population maintenance; GO:1902617|response to fluoride; GO:1903243|negative regulation of cardiac muscle hypertrophy in response to stress; GO:2000177|regulation of neural precursor cell proliferation; GO:2000377|regulation of reactive oxygen species metabolic process"	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005829|cytosol	"GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0001223|transcription coactivator binding; GO:0001227|DNA-binding transcription repressor activity, RNA polymerase II-specific; GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity; GO:0008013|beta-catenin binding; GO:0008134|transcription factor binding; GO:0031625|ubiquitin protein ligase binding; GO:0043565|sequence-specific DNA binding; GO:0051721|protein phosphatase 2A binding"	ko:K07201|FOXO1	ko04068|FoxO signaling pathway; ko04152|AMPK signaling pathway; ko04211|Longevity regulating pathway; ko04213|Longevity regulating pathway - multiple species; ko04910|Insulin signaling pathway; ko04919|Thyroid hormone signaling pathway; ko04922|Glucagon signaling pathway; ko04931|Insulin resistance; ko04933|AGE-RAGE signaling pathway in diabetic complications; ko05200|Pathways in cancer; ko05202|Transcriptional misregulation in cancer; ko05215|Prostate cancer	5728	NP_989659.1	NP_989659.1 forkhead box protein O1 [Gallus gallus]	sp|G3V7R4|FOXO1_RAT	sp|G3V7R4|FOXO1_RAT Forkhead box protein O1 OS=Rattus norvegicus GN=Foxo1 PE=1 SV=1	59729.ENSTGUP00000012368	Forkhead box protein O1 (Forkhead box protein O1A)(Forkhead in rhabdomyosarcoma) [Taeniopygi [...] 	COG5025	KOG2294	_	"PF16675.2|FOXO_KIX_bdg|KIX-binding domain of forkhead box O, CR2|ENSGALT00000080109|m.4365:497-577;PF00250.15|Forkhead|Forkhead domain|ENSGALT00000080109|m.4365:235-316;PF16676.2|FOXO-TAD|Transactivation domain of FOXO protein family|ENSGALT00000080109|m.4365:670-709"
ENSGALG00000017036	2.092805254	0.895550776	1.215447801	1.66E-05	4.53E-05	up	yes	2.668653922	1.847956075	1.761805764	0.791894033	0.879535727	1.015222569	1	172289679	172427314	+	LHFPL6	protein_coding	--	GO:0016021|integral component of membrane	--	--	--	1777	XP_417083.1	XP_417083.1 LHFPL tetraspan subfamily member 6 protein [Gallus gallus]	sp|Q5BJS2|LHPL6_RAT	sp|Q5BJS2|LHPL6_RAT LHFPL tetraspan subfamily member 6 protein OS=Rattus norvegicus GN=Lhfpl6 PE=2 SV=1	9031.ENSGALP00000027473	lipoma HMGIC fusion partner	_	KOG4026	_	PF10242.6|L_HMGIC_fpl|Lipoma HMGIC fusion partner-like protein|ENSGALT00000027525|m.4370:9-193
ENSGALG00000017050	5.783890151	11.79599536	-1.026915442	8.25E-13	4.65E-12	down	yes	5.218199646	5.225740407	6.9077304	11.58540378	10.86000719	12.9425751	1	173759258	173780357	+	SMAD9	protein_coding	"GO:0001657|ureteric bud development; GO:0006351|transcription, DNA-templated; GO:0006468|protein phosphorylation; GO:0007179|transforming growth factor beta receptor signaling pathway; GO:0030509|BMP signaling pathway; GO:0030901|midbrain development; GO:0030902|hindbrain development; GO:0051216|cartilage development; GO:0060348|bone development; GO:0060395|SMAD protein signal transduction; GO:0071407|cellular response to organic cyclic compound; GO:0071773|cellular response to BMP stimulus; GO:1901522|positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus"	GO:0005622|intracellular; GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005667|transcription factor complex; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0071141|SMAD protein complex	"GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity; GO:0030618|transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity; GO:0046872|metal ion binding"	"ko:K16791|SMAD9,SMAD8"	ko04350|TGF-beta signaling pathway; ko04550|Signaling pathways regulating pluripotency of stem cells	1656	XP_015133127.1	XP_015133127.1 mothers against decapentaplegic homolog 9 isoform X1 [Gallus gallus]	sp|O15198|SMAD9_HUMAN	sp|O15198|SMAD9_HUMAN Mothers against decapentaplegic homolog 9 OS=Homo sapiens GN=SMAD9 PE=1 SV=1	9031.ENSGALP00000027495	"MAD, mothers against decapentaplegic homolog 9 "	_	KOG3701	_	PF03166.11|MH2|MH2 domain|ENSGALT00000027547|m.4396:280-452;PF03165.13|MH1|MH1 domain|ENSGALT00000027547|m.4396:35-135
ENSGALG00000017075	2.343473578	6.536984597	-1.476038928	4.65E-49	1.63E-47	down	yes	2.094698796	2.394349472	2.541372466	5.929297933	6.976629949	6.705025909	1	175943342	176107764	-	FRY	protein_coding	GO:0000902|cell morphogenesis; GO:0031175|neuron projection development; GO:0090527|actin filament reorganization; GO:1904428|negative regulation of tubulin deacetylation	GO:0000922|spindle pole; GO:0005815|microtubule organizing center; GO:0005938|cell cortex; GO:0030427|site of polarized growth	GO:0004857|enzyme inhibitor activity	--	--	8955	XP_003640627.1	XP_003640627.1 protein furry homolog isoform X8 [Gallus gallus]	sp|Q5TBA9|FRY_HUMAN	sp|Q5TBA9|FRY_HUMAN Protein furry homolog OS=Homo sapiens GN=FRY PE=1 SV=1	9031.ENSGALP00000027526	"PREDICTED: Gallus gallus hypothetical LOC418915 (LOC418915), mRNA"	_	KOG1825	_	PF14222.3|MOR2-PAG1_N|Cell morphogenesis N-terminal|ENSGALT00000027578|m.4438:165-697;PF14225.3|MOR2-PAG1_C|Cell morphogenesis C-terminal|ENSGALT00000027578|m.4438:2017-2269;PF14228.3|MOR2-PAG1_mid|Cell morphogenesis central region|ENSGALT00000027578|m.4438:1188-1347;PF14228.3|MOR2-PAG1_mid|Cell morphogenesis central region|ENSGALT00000027578|m.4438:1391-1478;PF14228.3|MOR2-PAG1_mid|Cell morphogenesis central region|ENSGALT00000027578|m.4438:1614-1675;PF14228.3|MOR2-PAG1_mid|Cell morphogenesis central region|ENSGALT00000027578|m.4438:1762-1875
ENSGALG00000017120	9.116226758	3.69224087	1.30161974	4.49E-40	1.13E-38	up	yes	8.55732785	9.344442227	9.446910197	4.302292495	3.687601058	3.086829056	1	178932916	178982063	+	SACS	protein_coding	GO:0006457|protein folding; GO:0090084|negative regulation of inclusion body assembly	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005739|mitochondrion; GO:0030424|axon; GO:0030425|dendrite; GO:0070852|cell body fiber	GO:0030544|Hsp70 protein binding; GO:0051087|chaperone binding; GO:0070628|proteasome binding	ko:K17592|SACS	--	14404	XP_004938853.1	XP_004938853.1 sacsin isoform X1 [Gallus gallus]	sp|Q9NZJ4|SACS_HUMAN	sp|Q9NZJ4|SACS_HUMAN Sacsin OS=Homo sapiens GN=SACS PE=1 SV=2	9031.ENSGALP00000027606	spastic ataxia of Charlevoix-Saguenay (sacsin)	_	_	NOG80807	PF05168.11|HEPN|HEPN domain|ENSGALT00000099414|m.4521:4448-4569;PF00240.20|ubiquitin|Ubiquitin family|ENSGALT00000099414|m.4521:23-73
ENSGALG00000017126	27.81542122	56.72555839	-1.027849685	2.26E-33	4.24E-32	down	yes	28.0212329	28.08753033	27.33750043	59.44146458	58.26489084	52.47031974	1	179883997	179922552	+	ZDHHC20	protein_coding	GO:0018345|protein palmitoylation	GO:0005886|plasma membrane; GO:0016020|membrane; GO:0016021|integral component of membrane	GO:0016409|palmitoyltransferase activity; GO:0019706|protein-cysteine S-palmitoyltransferase activity	ko:K20028|ZDHHC2_15_20	--	1132	XP_015134738.1	XP_015134738.1 palmitoyltransferase ZDHHC20 isoform X1 [Gallus gallus]	sp|Q5W0Z9|ZDH20_HUMAN	sp|Q5W0Z9|ZDH20_HUMAN Probable palmitoyltransferase ZDHHC20 OS=Homo sapiens GN=ZDHHC20 PE=1 SV=1	9031.ENSGALP00000027614	"zinc finger, DHHC-type containing 20"	COG5273	KOG1315	_	PF01529.17|zf-DHHC|DHHC palmitoyltransferase|ENSGALT00000070093|m.4536:123-242
ENSGALG00000017155	4.551162031	9.60509479	-1.075899659	3.44E-05	9.03E-05	down	yes	4.278336295	3.714726182	5.660423615	10.54507429	8.549387961	9.720822118	1	181226287	181226754	-	C11orf87	protein_coding	--	--	--	--	--	468	XP_025002632.1	XP_025002632.1 uncharacterized protein C11orf87 homolog [Gallus gallus]	_	_	9031.ENSGALP00000027654	similar to hypothetical protein	_	_	NOG45015	_
ENSGALG00000017166	0.332712221	1.820418245	-2.417103792	0.000352722	0.000797518	down	yes	0.404693465	0.5934432	0	2.618265073	1.216416375	1.626573286	1	181732680	181742258	-	RAB39A	protein_coding	GO:0006914|autophagy; GO:0015031|protein transport; GO:0090383|phagosome acidification; GO:0090385|phagosome-lysosome fusion	GO:0005764|lysosome; GO:0005794|Golgi apparatus; GO:0005886|plasma membrane; GO:0030670|phagocytic vesicle membrane; GO:0045335|phagocytic vesicle	GO:0003924|GTPase activity; GO:0005525|GTP binding	ko:K07924|RAB39A	--	651	XP_021236063.1	XP_021236063.1 ras-related protein Rab-39A [Numida meleagris]	sp|Q8BHD0|RB39A_MOUSE	sp|Q8BHD0|RB39A_MOUSE Ras-related protein Rab-39A OS=Mus musculus GN=Rab39a PE=1 SV=1	_	_	_	_	_	"PF00071.19|Ras|Ras family|ENSGALT00000027726|m.4576:11-175;PF08477.10|Roc|Ras of Complex, Roc, domain of DAPkinase|ENSGALT00000027726|m.4576:11-129;PF00025.18|Arf|ADP-ribosylation factor family|ENSGALT00000027726|m.4576:9-172;PF04670.9|Gtr1_RagA|Gtr1/RagA G protein conserved region|ENSGALT00000027726|m.4576:13-145"
ENSGALG00000017170	6.351453392	15.57473755	-1.292705541	2.72E-41	7.32E-40	down	yes	6.444382517	6.284891495	6.325086165	15.81066383	15.18618131	15.7273675	1	181880177	181939483	+	ALKBH8	protein_coding	GO:0002098|tRNA wobble uridine modification; GO:0006974|cellular response to DNA damage stimulus; GO:0030488|tRNA methylation; GO:0055114|oxidation-reduction process	GO:0005634|nucleus; GO:0005829|cytosol	GO:0000049|tRNA binding; GO:0005506|iron ion binding; GO:0008270|zinc ion binding; GO:0016300|tRNA (uracil) methyltransferase activity; GO:0016706|2-oxoglutarate-dependent dioxygenase activity	ko:K10770|ALKBH8	--	2198	XP_417166.3	XP_417166.3 alkylated DNA repair protein alkB homolog 8 isoform X4 [Gallus gallus]	sp|Q95K79|ALKB8_MACFA	sp|Q95K79|ALKB8_MACFA Alkylated DNA repair protein alkB homolog 8 OS=Macaca fascicularis GN=ALKBH8 PE=2 SV=1	9031.ENSGALP00000027679	"alkB, alkylation repair homolog 8 (E. coli)"	COG0500;COG3145	KOG1331;KOG4176	_	"PF13532.3|2OG-FeII_Oxy_2|2OG-Fe(II) oxygenase superfamily|ENSGALT00000047290|m.4583:187-359;PF08241.9|Methyltransf_11|Methyltransferase domain|ENSGALT00000047290|m.4583:440-528;PF13649.3|Methyltransf_25|Methyltransferase domain|ENSGALT00000047290|m.4583:438-525;PF00076.19|RRM_1|RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)|ENSGALT00000047290|m.4583:74-128;PF05148.12|Methyltransf_8|Hypothetical methyltransferase|ENSGALT00000047290|m.4583:418-529"
ENSGALG00000017204	21.64354771	9.626330608	1.168047619	4.43E-25	5.58E-24	up	yes	22.26341615	21.66902367	20.99820331	8.408339632	11.17616175	9.294490445	1	186709569	186747771	+	SESN3	protein_coding	GO:0032868|response to insulin; GO:0034198|cellular response to amino acid starvation; GO:0038203|TORC2 signaling; GO:0042149|cellular response to glucose starvation; GO:0042593|glucose homeostasis; GO:0046626|regulation of insulin receptor signaling pathway; GO:0051896|regulation of protein kinase B signaling; GO:0071230|cellular response to amino acid stimulus; GO:1901031|regulation of response to reactive oxygen species; GO:1904262|negative regulation of TORC1 signaling	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0031932|TORC2 complex	GO:0016491|oxidoreductase activity	ko:K10141|SESN1_3	ko04115|p53 signaling pathway; ko04211|Longevity regulating pathway	1749	XP_015136040.1	XP_015136040.1 sestrin-3 [Gallus gallus]	sp|P58005|SESN3_HUMAN	sp|P58005|SESN3_HUMAN Sestrin-3 OS=Homo sapiens GN=SESN3 PE=1 SV=2	59729.ENSTGUP00000013196	Sestrin-3 [Taeniopygia guttata]	_	KOG3746	_	PF04636.10|PA26|PA26 p53-induced protein (sestrin)|ENSGALT00000104610|m.4670:50-490
ENSGALG00000017208	1.983479874	5.137414422	-1.3685589	2.43E-18	2.07E-17	down	yes	2.153198846	1.696153258	2.101087517	4.611869016	5.482500752	5.317873498	1	186814876	186872104	-	AMOTL1	protein_coding	GO:0003365|establishment of cell polarity involved in ameboidal cell migration; GO:0016055|Wnt signaling pathway; GO:0035329|hippo signaling; GO:0043536|positive regulation of blood vessel endothelial cell migration	GO:0005923|bicellular tight junction; GO:0008180|COP9 signalosome; GO:0016324|apical plasma membrane; GO:0030027|lamellipodium; GO:0031410|cytoplasmic vesicle	GO:0042802|identical protein binding	ko:K06104|AMOTL	ko04530|Tight junction	2961	XP_425649.3	XP_425649.3 angiomotin-like protein 1 isoform X1 [Gallus gallus]	sp|E1BEQ5|AMOL1_BOVIN	sp|E1BEQ5|AMOL1_BOVIN Angiomotin-like protein 1 OS=Bos taurus GN=AMOTL1 PE=3 SV=1	9031.ENSGALP00000027763	angiomotin like 1	_	_	NOG131728	PF12240.5|Angiomotin_C|Angiomotin C terminal|ENSGALT00000054573|m.4675:621-826
ENSGALG00000017228	0.544542265	1.25170519	-1.186005524	0.022291552	0.036706027	down	yes	1.138630092	0.345452927	0.149543775	0.900893532	1.568369932	1.285852106	1	187523990	187544411	-	MTNR1B	protein_coding	GO:0007623|circadian rhythm	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0008502|melatonin receptor activity	ko:K04286|MTNR1B	ko04080|Neuroactive ligand-receptor interaction; ko04713|Circadian entrainment	1342	NP_001280032.1	NP_001280032.1 melatonin receptor type 1B [Gallus gallus]	sp|P51050|MTR1B_CHICK	sp|P51050|MTR1B_CHICK Melatonin receptor type 1B (Fragment) OS=Gallus gallus PE=2 SV=1	_	_	_	_	_	PF00001.18|7tm_1|7 transmembrane receptor (rhodopsin family)|ENSGALT00000027844|m.4705:69-320;PF10328.6|7TM_GPCR_Srx|Serpentine type 7TM GPCR chemoreceptor Srx|ENSGALT00000027844|m.4705:61-333;PF10320.6|7TM_GPCR_Srsx|Serpentine type 7TM GPCR chemoreceptor Srsx|ENSGALT00000027844|m.4705:64-334
ENSGALG00000017296	2.208681041	5.721352532	-1.369173359	8.77E-15	5.75E-14	down	yes	2.077808367	2.011736444	2.536498311	5.751508353	6.247525764	5.165023481	1	72671873	72682871	+	KLHL42	protein_coding	GO:0000209|protein polyubiquitination; GO:0007049|cell cycle; GO:0032886|regulation of microtubule-based process; GO:0043161|proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0051301|cell division	GO:0005737|cytoplasm; GO:0005819|spindle; GO:0031463|Cul3-RING ubiquitin ligase complex	GO:0004842|ubiquitin-protein transferase activity	--	--	1978	XP_417237.1	XP_417237.1 kelch-like protein 42 [Gallus gallus]	sp|Q8BFQ9|KLH42_MOUSE	sp|Q8BFQ9|KLH42_MOUSE Kelch-like protein 42 OS=Mus musculus GN=Klhl42 PE=2 SV=1	9031.ENSGALP00000036492	kelch domain containing 5	_	KOG1072	_	PF01344.22|Kelch_1|Kelch motif|ENSGALT00000027951|m.2187:245-289;PF01344.22|Kelch_1|Kelch motif|ENSGALT00000027951|m.2187:292-332;PF13964.3|Kelch_6|Kelch motif|ENSGALT00000027951|m.2187:292-334;PF13854.3|Kelch_5|Kelch motif|ENSGALT00000027951|m.2187:331-360;PF00651.28|BTB|BTB/POZ domain|ENSGALT00000027951|m.2187:24-120
ENSGALG00000017302	0.291374465	0.723188027	-1.282626042	0.002573618	0.005067965	down	yes	0.162941134	0.46294075	0.248241511	0.635883877	0.813588113	0.720092091	1	195701721	195741913	+	SLCO2B1	protein_coding	GO:0001889|liver development; GO:0015721|bile acid and bile salt transport; GO:0043252|sodium-independent organic anion transport; GO:0071718|sodium-independent icosanoid transport	GO:0005887|integral component of plasma membrane; GO:0016324|apical plasma membrane	GO:0008514|organic anion transmembrane transporter activity; GO:0015125|bile acid transmembrane transporter activity; GO:0015347|sodium-independent organic anion transmembrane transporter activity	ko:K14352|SLCO2B	--	2523	XP_417242.3	XP_417242.3 solute carrier organic anion transporter family member 2B1 isoform X1 [Gallus gallus]	sp|Q9JHI3|SO2B1_RAT	sp|Q9JHI3|SO2B1_RAT Solute carrier organic anion transporter family member 2B1 OS=Rattus norvegicus GN=Slco2b1 PE=1 SV=1	9031.ENSGALP00000027908	annotation not avaliable	_	KOG3626	_	PF03137.17|OATP|Organic Anion Transporter Polypeptide (OATP) family|ENSGALT00000092878|m.4872:28-603;PF07690.13|MFS_1|Major Facilitator Superfamily|ENSGALT00000092878|m.4872:39-421;PF07648.12|Kazal_2|Kazal-type serine protease inhibitor domain|ENSGALT00000092878|m.4872:452-477
ENSGALG00000017326	0.312360714	0.135923359	1.143465091	0.005020724	0.009402573	up	yes	0.344659255	0.313966153	0.278456734	0.102142934	0.10739692	0.198230223	1	196400110	196613874	-	ARHGEF17	protein_coding	GO:0030036|actin cytoskeleton organization; GO:0035023|regulation of Rho protein signal transduction; GO:0043065|positive regulation of apoptotic process; GO:0051056|regulation of small GTPase mediated signal transduction	GO:0005829|cytosol	GO:0005085|guanyl-nucleotide exchange factor activity; GO:0005089|Rho guanyl-nucleotide exchange factor activity	ko:K20689|ARHGEF17	--	4302	XP_025002715.1	XP_025002715.1 rho guanine nucleotide exchange factor 17 [Gallus gallus]	sp|Q96PE2|ARHGH_HUMAN	sp|Q96PE2|ARHGH_HUMAN Rho guanine nucleotide exchange factor 17 OS=Homo sapiens GN=ARHGEF17 PE=1 SV=1	59729.ENSTGUP00000013876	Rho guanine nucleotide exchange factor 17 (164 kDa Rho-specific guanine-nucleotide exchange  [...] 	_	KOG3522	_	PF00621.17|RhoGEF|RhoGEF domain|ENSGALT00000027999|m.4926:713-895
ENSGALG00000017358	109.1230536	51.54999683	1.081764043	2.26E-46	7.23E-45	up	yes	103.7055024	112.7236615	110.939997	47.03810925	58.01678526	49.59509599	19	4382201	4400820	+	YWHAG	protein_coding	GO:0000086|G2/M transition of mitotic cell cycle; GO:0006469|negative regulation of protein kinase activity; GO:0006605|protein targeting; GO:0009966|regulation of signal transduction; GO:0010389|regulation of G2/M transition of mitotic cell cycle; GO:0032869|cellular response to insulin stimulus; GO:0045664|regulation of neuron differentiation; GO:0048167|regulation of synaptic plasticity; GO:0061024|membrane organization; GO:0097711|ciliary basal body-plasma membrane docking; GO:1900740|positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	GO:0005739|mitochondrion; GO:0005829|cytosol; GO:0005925|focal adhesion; GO:0016020|membrane; GO:0030659|cytoplasmic vesicle membrane; GO:0043209|myelin sheath; GO:0070062|extracellular exosome	GO:0003723|RNA binding; GO:0005080|protein kinase C binding; GO:0005159|insulin-like growth factor receptor binding; GO:0008426|protein kinase C inhibitor activity; GO:0019904|protein domain specific binding; GO:0030971|receptor tyrosine kinase binding; GO:0042802|identical protein binding	ko:K16198|YWHAG_H	ko04110|Cell cycle; ko04114|Oocyte meiosis; ko04151|PI3K-Akt signaling pathway; ko04390|Hippo signaling pathway; ko05169|Epstein-Barr virus infection; ko05203|Viral carcinogenesis	3341	BAE28625.1	"BAE28625.1 unnamed protein product, partial [Mus musculus]"	sp|P61981|1433G_HUMAN	sp|P61981|1433G_HUMAN 14-3-3 protein gamma OS=Homo sapiens GN=YWHAG PE=1 SV=2	_	_	_	_	_	PF00244.17|14-3-3|14-3-3 protein|ENSGALT00000028042|m.13687:63-287
ENSGALG00000017362	0.189481851	0.390031369	-1.003855637	0.01816746	0.030425144	down	yes	0.208265174	0.171787733	0.188392647	0.352523556	0.555984778	0.261585773	13	12143095	12173099	+	HAVCR1	protein_coding	--	GO:0016021|integral component of membrane	GO:0001786|phosphatidylserine binding	"ko:K20413|HAVCR1,CD365"	--	3799	NP_001292507.1	NP_001292507.1 hepatitis A virus cellular receptor 2 isoform 1 precursor [Gallus gallus]	sp|Q96H15|TIMD4_HUMAN	sp|Q96H15|TIMD4_HUMAN T-cell immunoglobulin and mucin domain-containing protein 4 OS=Homo sapiens GN=TIMD4 PE=1 SV=2	59729.ENSTGUP00000000683	Hepatitis A virus cellular receptor 2 Precursor (HAVcr-2)(T-cell immunoglobulin and mucin do [...] 	_	_	NOG41841	PF07686.14|V-set|Immunoglobulin V-set domain|ENSGALT00000089068|m.8786:25-127;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000089068|m.8786:25-116
ENSGALG00000017394	143.1036956	50.34199257	1.507040965	2.48E-111	4.17E-109	up	yes	139.59143	145.6441169	144.0755399	49.76978904	54.92547261	46.33071607	2	7910368	7918977	+	INSIG1	protein_coding	GO:0006641|triglyceride metabolic process; GO:0006695|cholesterol biosynthetic process; GO:0010894|negative regulation of steroid biosynthetic process; GO:0032933|SREBP signaling pathway; GO:0042472|inner ear morphogenesis; GO:0042474|middle ear morphogenesis; GO:0045599|negative regulation of fat cell differentiation; GO:0045717|negative regulation of fatty acid biosynthetic process; GO:0060021|roof of mouth development; GO:0060363|cranial suture morphogenesis; GO:1901303|negative regulation of cargo loading into COPII-coated vesicle	GO:0032937|SREBP-SCAP-Insig complex	--	--	--	3099	NP_001026137.1	NP_001026137.1 insulin-induced gene 1 protein [Gallus gallus]	sp|Q5ZMT9|INSI1_CHICK	sp|Q5ZMT9|INSI1_CHICK Insulin-induced gene 1 protein OS=Gallus gallus GN=INSIG1 PE=2 SV=1	_	_	_	_	_	PF07281.9|INSIG|Insulin-induced protein (INSIG)|ENSGALT00000028082|m.14745:62-242
ENSGALG00000017462	8.864321117	27.76746078	-1.646206061	3.89E-94	4.19E-92	down	yes	8.283967563	9.005416442	9.303579344	25.64973146	29.6455527	28.00709818	13	17291960	17350348	-	FNIP1	protein_coding	--	GO:0005737|cytoplasm	GO:0042030|ATPase inhibitor activity; GO:0051087|chaperone binding	ko:K20400|FNIP1	ko04150|mTOR signaling pathway	4441	XP_015731045.1	XP_015731045.1 PREDICTED: folliculin-interacting protein 1 isoform X3 [Coturnix japonica]	sp|Q5W4S4|FNIP1_CHICK	sp|Q5W4S4|FNIP1_CHICK Folliculin-interacting protein 1 OS=Gallus gallus GN=FNIP1 PE=3 SV=1	9031.ENSGALP00000039227	Folliculin-interacting protein 1 ; May be involved in energy and/or nutrient sensing (By sim [...] 	_	KOG3693	_	PF14637.3|FNIP_M|Folliculin-interacting protein middle domain|ENSGALT00000068857|m.9048:322-551;PF14638.3|FNIP_C|Folliculin-interacting protein C-terminus|ENSGALT00000068857|m.9048:980-1166;PF14636.3|FNIP_N|Folliculin-interacting protein N-terminus|ENSGALT00000068857|m.9048:40-160
ENSGALG00000017715	2.421759097	1.08085289	1.156543759	4.05E-05	0.000105244	up	yes	2.448342491	1.769843364	3.047091437	1.089562334	1.036501387	1.116494949	23	5106695	5112284	+	TINAGL1	protein_coding	GO:0006955|immune response; GO:0007155|cell adhesion	GO:0005615|extracellular space; GO:0005737|cytoplasm; GO:0031012|extracellular matrix; GO:0070062|extracellular exosome	GO:0005044|scavenger receptor activity; GO:0008234|cysteine-type peptidase activity; GO:0030247|polysaccharide binding; GO:0043236|laminin binding	--	--	1422	XP_428202.3	XP_428202.3 tubulointerstitial nephritis antigen-like [Gallus gallus]	sp|Q99JR5|TINAL_MOUSE	sp|Q99JR5|TINAL_MOUSE Tubulointerstitial nephritis antigen-like OS=Mus musculus GN=Tinagl1 PE=1 SV=1	28377.ENSACAP00000012225	tubulointerstitial nephritis antigen-like 1	_	KOG1544	_	PF00112.20|Peptidase_C1|Papain family cysteine protease|ENSGALT00000100581|m.5677:202-419
ENSGALG00000018557	17.09287814	5.643956164	1.596906525	3.68E-39	8.82E-38	up	yes	16.1875717	18.37398034	16.71708238	6.197899832	5.356588179	5.377380483	4	73665483	73667513	-	SOD3	protein_coding	GO:0001666|response to hypoxia; GO:0034599|cellular response to oxidative stress; GO:0046688|response to copper ion	GO:0005576|extracellular region; GO:0005615|extracellular space; GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005796|Golgi lumen; GO:0031012|extracellular matrix; GO:0070062|extracellular exosome	GO:0004784|superoxide dismutase activity; GO:0005507|copper ion binding; GO:0008201|heparin binding; GO:0008270|zinc ion binding	ko:K16627|SOD3	--	1455	XP_015141186.2	XP_015141186.2 extracellular superoxide dismutase [Cu-Zn] [Gallus gallus]	sp|P08294|SODE_HUMAN	sp|P08294|SODE_HUMAN Extracellular superoxide dismutase [Cu-Zn] OS=Homo sapiens GN=SOD3 PE=1 SV=2	_	_	_	_	_	PF00080.17|Sod_Cu|Copper/zinc superoxide dismutase (SODC)|ENSGALT00000023256|m.1275:156-279
ENSGALG00000018815	0.071495438	0.286212174	-1.861839735	0.000267393	0.000614475	down	yes	0.047394728	0.112937032	0.054154553	0.294152779	0.299911069	0.264572673	27	6812837	6820148	-	PCGF2	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0001701|in utero embryonic development; GO:0006351|transcription, DNA-templated; GO:0009952|anterior/posterior pattern specification; GO:0016573|histone acetylation; GO:0036353|histone H2A-K119 monoubiquitination; GO:0048704|embryonic skeletal system morphogenesis; GO:0070301|cellular response to hydrogen peroxide; GO:2001234|negative regulation of apoptotic signaling pathway"	GO:0000790|nuclear chromatin; GO:0001739|sex chromatin; GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0016604|nuclear body; GO:0031519|PcG protein complex; GO:0035102|PRC1 complex	GO:0003677|DNA binding; GO:0003682|chromatin binding; GO:0003700|DNA-binding transcription factor activity; GO:0046872|metal ion binding	"ko:K11460|PCGF2,RNF110"	ko04550|Signaling pathways regulating pluripotency of stem cells	4322	XP_015154995.1	XP_015154995.1 polycomb group RING finger protein 2 isoform X1 [Gallus gallus]	sp|P35227|PCGF2_HUMAN	sp|P35227|PCGF2_HUMAN Polycomb group RING finger protein 2 OS=Homo sapiens GN=PCGF2 PE=1 SV=1	9796.ENSECAP00000005809	polycomb group ring finger 2	_	KOG2660	_	"PF16207.2|RAWUL|RAWUL domain RING finger- and WD40-associated ubiquitin-like|ENSGALT00000094502|m.9152:516-580;PF13923.3|zf-C3HC4_2|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000094502|m.9152:370-409;PF00097.22|zf-C3HC4|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000094502|m.9152:371-409"
ENSGALG00000019077	8.763831077	18.16479089	-1.05065993	1.02E-26	1.39E-25	down	yes	7.816861482	9.639367118	8.83526463	17.08408607	20.78346316	16.62682344	1	178515945	178724914	+	ENSGALG00000019077	protein_coding	GO:0016477|cell migration; GO:0030032|lamellipodium assembly; GO:0030334|regulation of cell migration; GO:0035023|regulation of Rho protein signal transduction; GO:0035556|intracellular signal transduction; GO:0046847|filopodium assembly	GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0030027|lamellipodium; GO:0030175|filopodium; GO:0032587|ruffle membrane	GO:0005085|guanyl-nucleotide exchange factor activity; GO:0030676|Rac guanyl-nucleotide exchange factor activity; GO:0042802|identical protein binding	"ko:K05769|ARHGEF4_29,ASEF1_2"	ko04810|Regulation of actin cytoskeleton	5173	XP_015134594.1	XP_015134594.1 spermatogenesis-associated protein 13 isoform X1 [Gallus gallus]	sp|Q5DU57|SPT13_MOUSE	sp|Q5DU57|SPT13_MOUSE Spermatogenesis-associated protein 13 OS=Mus musculus GN=Spata13 PE=1 SV=2	_	_	_	_	_	PF00621.17|RhoGEF|RhoGEF domain|ENSGALT00000102304|m.4511:980-1158;PF00169.26|PH|PH domain|ENSGALT00000102304|m.4511:1193-1293;PF00018.25|SH3_1|SH3 domain|ENSGALT00000102304|m.4511:890-934;PF14604.3|SH3_9|Variant SH3 domain|ENSGALT00000102304|m.4511:890-937;PF07653.14|SH3_2|Variant SH3 domain|ENSGALT00000102304|m.4511:893-938
ENSGALG00000019114	54.09022085	24.96357282	1.115232249	1.53E-30	2.48E-29	up	yes	52.03190117	55.80702233	54.43173904	28.79553271	22.57717595	23.51800981	1	147451550	147510983	-	CLDN10	protein_coding	GO:0006811|ion transport	GO:0005737|cytoplasm; GO:0005886|plasma membrane; GO:0005923|bicellular tight junction; GO:0016021|integral component of membrane	GO:0005198|structural molecule activity	ko:K06087|CLDN	ko04514|Cell adhesion molecules (CAMs); ko04530|Tight junction; ko04670|Leukocyte transendothelial migration; ko05160|Hepatitis C	963	NP_001264696.1	NP_001264696.1 claudin-10 isoform 1 precursor [Gallus gallus]	sp|Q5E9L0|CLD10_BOVIN	sp|Q5E9L0|CLD10_BOVIN Claudin-10 OS=Bos taurus GN=CLDN10 PE=2 SV=1	9031.ENSGALP00000029552	annotation not avaliable	_	_	NOG42372	PF00822.17|PMP22_Claudin|PMP-22/EMP/MP20/Claudin family|ENSGALT00000030190|m.4015:10-181
ENSGALG00000019178	7.089885343	14.23208506	-1.004292743	1.47E-30	2.39E-29	down	yes	7.187378542	7.616918062	6.465359426	14.57870539	13.84424721	14.27330259	1	110390796	110421676	-	PRDM15	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0016604|nuclear body	GO:0003677|DNA binding; GO:0008168|methyltransferase activity; GO:0046872|metal ion binding	--	--	4078	XP_015156553.1	XP_015156553.1 PR domain zinc finger protein 15 isoform X4 [Gallus gallus]	sp|P57071|PRD15_HUMAN	sp|P57071|PRD15_HUMAN PR domain zinc finger protein 15 OS=Homo sapiens GN=PRDM15 PE=1 SV=4	9031.ENSGALP00000025970	PR domain containing 15	COG5048	KOG1721	_	"PF00096.23|zf-C2H2|Zinc finger, C2H2 type|ENSGALT00000090664|m.3152:395-417;PF00096.23|zf-C2H2|Zinc finger, C2H2 type|ENSGALT00000090664|m.3152:741-763;PF13894.3|zf-C2H2_4|C2H2-type zinc finger|ENSGALT00000090664|m.3152:395-417;PF13894.3|zf-C2H2_4|C2H2-type zinc finger|ENSGALT00000090664|m.3152:561-581;PF13894.3|zf-C2H2_4|C2H2-type zinc finger|ENSGALT00000090664|m.3152:741-763;PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000090664|m.3152:510-529"
ENSGALG00000019358	16.09744355	6.913743942	1.218103263	6.72E-22	7.04E-21	up	yes	16.15017971	16.47201185	15.6701391	6.363331882	7.225898054	7.152001889	1	34486674	34489660	-	LLPH	protein_coding	GO:0060999|positive regulation of dendritic spine development; GO:0097484|dendrite extension	GO:0005694|chromosome; GO:0005730|nucleolus	GO:0001099|basal RNA polymerase II transcription machinery binding; GO:0003723|RNA binding	--	--	1150	NP_001072969.1	NP_001072969.1 protein LLP homolog [Gallus gallus]	sp|Q5ZHK9|LLPH_CHICK	sp|Q5ZHK9|LLPH_CHICK Protein LLP homolog OS=Gallus gallus GN=LLPH PE=3 SV=1	_	_	_	_	_	PF10169.6|Laps|Learning-associated protein|ENSGALT00000057146|m.843:20-124
ENSGALG00000019552	5.422415459	27.71499384	-2.351521417	4.02E-06	1.19E-05	down	yes	9.471121152	3.256864583	3.539260643	27.35765736	24.78685654	31.00046763	2	67665297	67674062	-	SERPINB10	protein_coding	GO:0035722|interleukin-12-mediated signaling pathway; GO:0042060|wound healing; GO:0042730|fibrinolysis; GO:0043066|negative regulation of apoptotic process	GO:0005576|extracellular region; GO:0005615|extracellular space; GO:0005737|cytoplasm; GO:0005886|plasma membrane	GO:0004867|serine-type endopeptidase inhibitor activity	"ko:K19821|SERPINB2,PAI2"	ko04610|Complement and coagulation cascades	2064	XP_418982.1	XP_418982.1 serpin B10 [Gallus gallus]	sp|P05120|PAI2_HUMAN	sp|P05120|PAI2_HUMAN Plasminogen activator inhibitor 2 OS=Homo sapiens GN=SERPINB2 PE=1 SV=2	9031.ENSGALP00000020952	"serpin peptidase inhibitor, clade B (ovalbumin), member 2"	COG4826	KOG2392	_	PF00079.17|Serpin|Serpin (serine protease inhibitor)|ENSGALT00000020982|m.1034:28-433
ENSGALG00000019690	0.709711557	2.416069207	-1.753129976	7.15E-11	3.42E-10	down	yes	0.724035356	0.924729709	0.480369606	2.574095615	2.466333578	2.207778428	2	6292140	6311275	-	WDR86	protein_coding	--	--	--	--	--	2256	XP_001233535.2	XP_001233535.2 WD repeat-containing protein 86 isoform X1 [Gallus gallus]	sp|Q86TI4|WDR86_HUMAN	sp|Q86TI4|WDR86_HUMAN WD repeat-containing protein 86 OS=Homo sapiens GN=WDR86 PE=2 SV=3	_	_	_	_	_	"PF00400.29|WD40|WD domain, G-beta repeat|ENSGALT00000054972|m.14711:8-43;PF00400.29|WD40|WD domain, G-beta repeat|ENSGALT00000054972|m.14711:48-83;PF00400.29|WD40|WD domain, G-beta repeat|ENSGALT00000054972|m.14711:87-123;PF00400.29|WD40|WD domain, G-beta repeat|ENSGALT00000054972|m.14711:128-182;PF00400.29|WD40|WD domain, G-beta repeat|ENSGALT00000054972|m.14711:187-225;PF00400.29|WD40|WD domain, G-beta repeat|ENSGALT00000054972|m.14711:229-264;PF00400.29|WD40|WD domain, G-beta repeat|ENSGALT00000054972|m.14711:311-345"
ENSGALG00000019716	12.63521727	3.534643373	1.834879436	3.62E-47	1.18E-45	up	yes	13.40550677	11.85712095	12.6430241	3.301608805	3.976371697	3.325949617	27	7336035	7340414	-	KRT20	protein_coding	GO:0006915|apoptotic process; GO:0033554|cellular response to stress; GO:0045109|intermediate filament organization; GO:0050708|regulation of protein secretion	GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005882|intermediate filament	GO:0005198|structural molecule activity	ko:K07604|KRT1	--	1981	NP_001264910.1	"NP_001264910.1 keratin, type I cytoskeletal 20 [Gallus gallus]"	sp|Q9D312|K1C20_MOUSE	"sp|Q9D312|K1C20_MOUSE Keratin, type I cytoskeletal 20 OS=Mus musculus GN=Krt20 PE=1 SV=1"	9031.ENSGALP00000006089	keratin 20	_	KOG0508	_	PF00038.18|Filament|Intermediate filament protein|ENSGALT00000006099|m.9305:182-491
ENSGALG00000019845	34.23960939	14.66176028	1.223045562	1.74E-23	2.00E-22	up	yes	31.38388957	35.4748216	35.86011701	16.28973327	13.81162986	13.88391772	3	107433951	107437008	+	AvBD9	protein_coding	GO:0031640|killing of cells of other organism; GO:0050829|defense response to Gram-negative bacterium; GO:0050832|defense response to fungus	GO:0005615|extracellular space; GO:0005623|cell; GO:0005737|cytoplasm	--	--	--	685	NP_001001611.1	NP_001001611.1 gallinacin-9 preproprotein [Gallus gallus]	sp|Q6QLR1|GLL9_CHICK	sp|Q6QLR1|GLL9_CHICK Gallinacin-9 OS=Gallus gallus GN=GAL9 PE=2 SV=1	9031.ENSGALP00000035930	Gallinacin-9 Precursor (Gal-9)(Beta-defensin 9)(Gallinacin-6)(Gal-6); Has bactericidal activ [...] 	_	_	NOG254530	_
ENSGALG00000019894	11.86511475	5.309239071	1.15864967	9.81E-14	5.94E-13	up	yes	11.56763084	13.03333939	10.99437402	5.608583902	5.20453678	5.114596532	3	88430716	88436533	-	TMEM14A	protein_coding	GO:0043066|negative regulation of apoptotic process; GO:1901029|negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	GO:0005789|endoplasmic reticulum membrane; GO:0016021|integral component of membrane; GO:0031966|mitochondrial membrane	--	--	--	993	XP_015140404.1	XP_015140404.1 transmembrane protein 14A isoform X1 [Gallus gallus]	sp|P56982|TM14A_BOVIN	sp|P56982|TM14A_BOVIN Transmembrane protein 14A OS=Bos taurus GN=TMEM14A PE=3 SV=1	9031.ENSGALP00000030997	transmembrane protein 14A	_	KOG4267	_	_
ENSGALG00000019932	0.095553121	0.251439325	-1.30850693	0.000346443	0.000783762	down	yes	0.073163593	0.112163911	0.101331859	0.255188726	0.236748546	0.262380703	3	66959618	67045327	-	ENSGALG00000019932	protein_coding	--	--	--	--	--	7666	XP_025004995.1	XP_025004995.1 uncharacterized protein LOC101748060 [Gallus gallus]	sp|A2VCL2|CC162_HUMAN	sp|A2VCL2|CC162_HUMAN Coiled-coil domain-containing protein 162 OS=Homo sapiens GN=CCDC162P PE=2 SV=3	_	_	_	_	_	PF15082.3|DUF4549|Domain of unknown function (DUF4549)|ENSGALT00000097671|m.12404:15-156
ENSGALG00000020151	0.678303276	0.219954541	1.581695687	0.002226688	0.004437583	up	yes	0.755427801	0.392331893	0.887150133	0.153916099	0.236525406	0.269422118	4	65036791	65049180	+	NMU	protein_coding	"GO:0001696|gastric acid secretion; GO:0006940|regulation of smooth muscle contraction; GO:0007165|signal transduction; GO:0007186|G protein-coupled receptor signaling pathway; GO:0007218|neuropeptide signaling pathway; GO:0007586|digestion; GO:0009648|photoperiodism; GO:0019233|sensory perception of pain; GO:0042755|eating behavior; GO:0045187|regulation of circadian sleep/wake cycle, sleep; GO:0045987|positive regulation of smooth muscle contraction; GO:0046887|positive regulation of hormone secretion; GO:0050806|positive regulation of synaptic transmission; GO:2000252|negative regulation of feeding behavior; GO:2000821|regulation of grooming behavior"	GO:0005576|extracellular region; GO:0043195|terminal bouton	GO:0005102|signaling receptor binding; GO:0042922|neuromedin U receptor binding	ko:K05249|NMU	--	1674	NP_001264850.1	NP_001264850.1 neuromedin-U-25 isoform 1 precursor [Gallus gallus]	sp|P48645|NMU_HUMAN	sp|P48645|NMU_HUMAN Neuromedin-U OS=Homo sapiens GN=NMU PE=1 SV=1	9031.ENSGALP00000031462	Neuromedin-U-25; Stimulates uterine smooth muscle contraction and causes selective vasoconst [...] 	_	_	NOG47198	PF02070.12|NMU|Neuromedin U|ENSGALT00000032098|m.1082:149-173
ENSGALG00000020253	1.167874328	2.8392563	-1.274399782	6.73E-07	2.19E-06	down	yes	0.818447554	1.158787642	1.526387787	2.887491642	3.036017257	2.59426	4	20616732	20625403	-	ENSGALG00000020253	protein_coding	GO:0000910|cytokinesis; GO:0046602|regulation of mitotic centrosome separation; GO:0060236|regulation of mitotic spindle organization; GO:0090307|mitotic spindle assembly; GO:1902412|regulation of mitotic cytokinesis	GO:0000235|astral microtubule; GO:0005737|cytoplasm; GO:0005818|aster; GO:0015630|microtubule cytoskeleton; GO:0051233|spindle midzone; GO:0072686|mitotic spindle; GO:1990023|mitotic spindle midzone	GO:0008017|microtubule binding	ko:K10434|MAP9	--	1867	XP_015140834.1	XP_015140834.1 microtubule-associated protein 9 isoform X2 [Gallus gallus]	sp|Q3TRR0|MAP9_MOUSE	sp|Q3TRR0|MAP9_MOUSE Microtubule-associated protein 9 OS=Mus musculus GN=Map9 PE=1 SV=2	_	_	_	_	_	_
ENSGALG00000020316	0.618698816	5.43261311	-3.113858535	3.85E-36	8.03E-35	down	yes	0.449327082	0.790672816	0.616096549	5.487307164	5.805102471	5.005429695	4	2834589	2850667	-	IL13RA2	protein_coding	GO:0002638|negative regulation of immunoglobulin production; GO:0016064|immunoglobulin mediated immune response; GO:0043305|negative regulation of mast cell degranulation	GO:0005576|extracellular region; GO:0016021|integral component of membrane	GO:0004896|cytokine receptor activity	"ko:K05077|IL13RA2,CD213A2"	ko04630|Jak-STAT signaling pathway	1759	XP_015133714.1	XP_015133714.1 interleukin-13 receptor subunit alpha-2 isoform X1 [Gallus gallus]	sp|O88786|I13R2_MOUSE	sp|O88786|I13R2_MOUSE Interleukin-13 receptor subunit alpha-2 OS=Mus musculus GN=Il13ra2 PE=2 SV=1	_	_	_	_	_	"PF09240.7|IL6Ra-bind|Interleukin-6 receptor alpha chain, binding|ENSGALT00000053660|m.16208:149-241"
ENSGALG00000020386	1.820388199	0.592618404	1.602833017	2.35E-07	8.05E-07	up	yes	1.452345345	2.172316171	1.836503081	0.458889539	0.735228513	0.583737161	5	46575153	46577714	+	BDKRB1	protein_coding	GO:0001933|negative regulation of protein phosphorylation; GO:0002687|positive regulation of leukocyte migration; GO:0006954|inflammatory response; GO:0007204|positive regulation of cytosolic calcium ion concentration; GO:0007205|protein kinase C-activating G protein-coupled receptor signaling pathway; GO:0009612|response to mechanical stimulus; GO:0016477|cell migration; GO:0019233|sensory perception of pain; GO:0030308|negative regulation of cell growth; GO:0032496|response to lipopolysaccharide; GO:0045776|negative regulation of blood pressure; GO:0051281|positive regulation of release of sequestered calcium ion into cytosol	GO:0005783|endoplasmic reticulum; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0043005|neuron projection	GO:0004947|bradykinin receptor activity; GO:0042277|peptide binding	ko:K03915|BDKRB1	ko04020|Calcium signaling pathway; ko04080|Neuroactive ligand-receptor interaction; ko04610|Complement and coagulation cascades; ko04750|Inflammatory mediator regulation of TRP channels; ko04810|Regulation of actin cytoskeleton; ko05200|Pathways in cancer	1814	NP_001074189.1	NP_001074189.1 B1 bradykinin receptor [Gallus gallus]	sp|P46663|BKRB1_HUMAN	sp|P46663|BKRB1_HUMAN B1 bradykinin receptor OS=Homo sapiens GN=BDKRB1 PE=1 SV=3	9031.ENSGALP00000031881	Bradykinin receptor B1 	_	KOG3656	_	PF00001.18|7tm_1|7 transmembrane receptor (rhodopsin family)|ENSGALT00000032517|m.3813:48-310;PF10324.6|7TM_GPCR_Srw|Serpentine type 7TM GPCR chemoreceptor Srw|ENSGALT00000032517|m.3813:103-326
ENSGALG00000020390	25.44715108	4.832248558	2.394321934	3.78E-105	5.31E-103	up	yes	27.31881945	25.24688806	23.77574575	4.519386916	4.831493292	5.145865466	5	45766602	45774064	-	ENSGALG00000020390	protein_coding	GO:0006953|acute-phase response; GO:0030162|regulation of proteolysis	GO:0005615|extracellular space	GO:0004867|serine-type endopeptidase inhibitor activity	ko:K04525|SERPINA	--	1570	XP_421344.1	XP_421344.1 alpha-1-antitrypsin isoform X1 [Gallus gallus]	sp|O00394|A1AT_CHLAE	sp|O00394|A1AT_CHLAE Alpha-1-antitrypsin (Fragment) OS=Chlorocebus aethiops GN=SERPINA1 PE=2 SV=1	9031.ENSGALP00000017843	"serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5"	COG4826	KOG2392	_	PF00079.17|Serpin|Serpin (serine protease inhibitor)|ENSGALT00000017864|m.3793:57-419
ENSGALG00000020523	7.562942132	3.562890768	1.083762097	8.45E-19	7.39E-18	up	yes	7.669532604	7.790505763	7.228788029	3.031172923	3.888494879	3.769004501	Z	67319346	67323518	+	ENSGALG00000020523	protein_coding	"GO:0000209|protein polyubiquitination; GO:0006351|transcription, DNA-templated; GO:0006511|ubiquitin-dependent protein catabolic process; GO:0006513|protein monoubiquitination; GO:0006974|cellular response to DNA damage stimulus; GO:0008630|intrinsic apoptotic signaling pathway in response to DNA damage; GO:0010842|retina layer formation; GO:0016925|protein sumoylation; GO:0034504|protein localization to nucleus; GO:0035845|photoreceptor cell outer segment organization; GO:0042127|regulation of cell population proliferation; GO:0042771|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; GO:0043066|negative regulation of apoptotic process; GO:0043161|proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0045893|positive regulation of transcription, DNA-templated; GO:0046548|retinal rod cell development; GO:0046549|retinal cone cell development; GO:0051443|positive regulation of ubiquitin-protein transferase activity; GO:0051457|maintenance of protein location in nucleus; GO:0070936|protein K48-linked ubiquitination"	GO:0000151|ubiquitin ligase complex; GO:0000922|spindle pole; GO:0000930|gamma-tubulin complex; GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005814|centriole; GO:0016605|PML body; GO:0016607|nuclear speck; GO:0030496|midbody; GO:0032391|photoreceptor connecting cilium; GO:0036064|ciliary basal body	GO:0003677|DNA binding; GO:0003823|antigen binding; GO:0004842|ubiquitin-protein transferase activity; GO:0019789|SUMO transferase activity; GO:0044547|DNA topoisomerase binding; GO:0046872|metal ion binding; GO:0061630|ubiquitin protein ligase activity	ko:K10631|TOPORS	--	3387	XP_004949581.1	XP_004949581.1 E3 ubiquitin-protein ligase Topors isoform X1 [Gallus gallus]	sp|Q9NS56|TOPRS_HUMAN	sp|Q9NS56|TOPRS_HUMAN E3 ubiquitin-protein ligase Topors OS=Homo sapiens GN=TOPORS PE=1 SV=1	_	_	_	_	_	"PF13923.3|zf-C3HC4_2|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000032768|m.11864:99-138;PF13920.3|zf-C3HC4_3|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000032768|m.11864:97-142;PF00097.22|zf-C3HC4|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000032768|m.11864:100-138;PF13639.3|zf-RING_2|Ring finger domain|ENSGALT00000032768|m.11864:99-139;PF13445.3|zf-RING_UBOX|RING-type zinc-finger|ENSGALT00000032768|m.11864:100-136"
ENSGALG00000020534	32.74051682	15.28902017	1.098078415	3.40E-48	1.16E-46	up	yes	33.46714283	33.45643802	31.2979696	14.76449459	16.32571559	14.77685034	Z	64365002	64369042	-	AK6	protein_coding	GO:0015949|nucleobase-containing small molecule interconversion	GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0015030|Cajal body; GO:0016020|membrane	GO:0004017|adenylate kinase activity; GO:0005524|ATP binding; GO:0050145|nucleoside monophosphate kinase activity	"ko:K18532|AK6,FAP7"	ko00230|Purine metabolism; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko01130|Biosynthesis of antibiotics; ko03008|Ribosome biogenesis in eukaryotes	3015	NP_001026504.1	NP_001026504.1 adenylate kinase isoenzyme 6 [Gallus gallus]	sp|Q9Y3D8|KAD6_HUMAN	sp|Q9Y3D8|KAD6_HUMAN Adenylate kinase isoenzyme 6 OS=Homo sapiens GN=AK6 PE=1 SV=1	9031.ENSGALP00000032152	hypothetical protein LOC425215 	COG1936	KOG3347	_	PF13238.3|AAA_18|AAA domain|ENSGALT00000032789|m.11794:26-146;PF13207.3|AAA_17|AAA domain|ENSGALT00000032789|m.11794:29-100
ENSGALG00000020557	11.66771455	23.63754433	-1.017932424	3.68E-40	9.27E-39	down	yes	11.86074316	11.86870637	11.27369412	22.29821162	25.43315188	23.18126948	Z	28093889	28397186	+	KDM4C	protein_coding	"GO:0001825|blastocyst formation; GO:0006351|transcription, DNA-templated; GO:0006357|regulation of transcription by RNA polymerase II; GO:0008284|positive regulation of cell population proliferation; GO:0010628|positive regulation of gene expression; GO:0033169|histone H3-K9 demethylation; GO:0045666|positive regulation of neuron differentiation; GO:0070544|histone H3-K36 demethylation; GO:1900113|negative regulation of histone H3-K9 trimethylation; GO:2000036|regulation of stem cell population maintenance; GO:2000736|regulation of stem cell differentiation"	GO:0000790|nuclear chromatin; GO:0005654|nucleoplasm; GO:0005721|pericentric heterochromatin	GO:0003682|chromatin binding; GO:0008270|zinc ion binding; GO:0019899|enzyme binding; GO:0032452|histone demethylase activity; GO:0032454|histone demethylase activity (H3-K9 specific); GO:0050681|androgen receptor binding; GO:0051864|histone demethylase activity (H3-K36 specific)	"ko:K06709|KDM4,JMJD2,JHDM3"	--	3618	XP_003643040.1	XP_003643040.1 lysine-specific demethylase 4C isoform X1 [Gallus gallus]	sp|Q9H3R0|KDM4C_HUMAN	sp|Q9H3R0|KDM4C_HUMAN Lysine-specific demethylase 4C OS=Homo sapiens GN=KDM4C PE=1 SV=2	9031.ENSGALP00000032199	annotation not avaliable	COG5141	KOG0958	_	"PF02373.19|JmjC|JmjC domain, hydroxylase|ENSGALT00000032836|m.11121:177-293;PF13832.3|zf-HC5HC2H_2|PHD-zinc-finger like domain|ENSGALT00000032836|m.11121:767-877;PF13771.3|zf-HC5HC2H|PHD-like zinc-binding domain|ENSGALT00000032836|m.11121:788-877;PF13831.3|PHD_2|PHD-finger|ENSGALT00000032836|m.11121:725-760;PF02375.14|JmjN|jmjN domain|ENSGALT00000032836|m.11121:17-51"
ENSGALG00000020647	1.798183735	0.689566341	1.3700085	9.37E-05	0.000230998	up	yes	1.45995461	1.946254524	1.988342071	0.698929995	0.612401058	0.75736797	8	25474003	25477526	-	LDLRAD1	protein_coding	--	GO:0016021|integral component of membrane	--	--	--	1191	XP_015146685.1	XP_015146685.1 low-density lipoprotein receptor class A domain-containing protein 1 [Gallus gallus]	sp|Q5T700|LRAD1_HUMAN	sp|Q5T700|LRAD1_HUMAN Low-density lipoprotein receptor class A domain-containing protein 1 OS=Homo sapiens GN=LDLRAD1 PE=1 SV=1	9031.ENSGALP00000032390	low density lipoprotein receptor class A domain containing 1	_	_	NOG132008	PF00057.15|Ldl_recept_a|Low-density lipoprotein receptor domain class A|ENSGALT00000033030|m.8022:38-68;PF00057.15|Ldl_recept_a|Low-density lipoprotein receptor domain class A|ENSGALT00000033030|m.8022:84-111
ENSGALG00000020679	0.298053994	1.474621832	-2.268840345	4.65E-08	1.72E-07	down	yes	0.321679421	0.400954572	0.171527988	1.415689836	1.679344064	1.328831595	6	28482182	28494460	+	PLEKHS1	protein_coding	--	--	--	--	--	1638	XP_025007606.1	XP_025007606.1 pleckstrin homology domain-containing family S member 1 isoform X1 [Gallus gallus]	sp|Q5SXH7|PKHS1_HUMAN	sp|Q5SXH7|PKHS1_HUMAN Pleckstrin homology domain-containing family S member 1 OS=Homo sapiens GN=PLEKHS1 PE=1 SV=2	9031.ENSGALP00000032459	annotation not avaliable	_	_	NOG75022	PF00169.26|PH|PH domain|ENSGALT00000033099|m.5308:24-134
ENSGALG00000020754	21.10989929	5.7135514	1.883620449	3.64E-37	8.14E-36	up	yes	21.78666161	20.23138668	21.31164957	6.787059468	4.460105912	5.893488819	6	23061953	23063322	+	ATP6V0E2	protein_coding	GO:1902600|proton transmembrane transport	"GO:0016020|membrane; GO:0016021|integral component of membrane; GO:0033179|proton-transporting V-type ATPase, V0 domain"	"GO:0046961|proton-transporting ATPase activity, rotational mechanism"	"ko:K02153|ATPeV0E,ATP6H"	ko00190|Oxidative phosphorylation; ko01100|Metabolic pathways; ko04145|Phagosome; ko04721|Synaptic vesicle cycle; ko04966|Collecting duct acid secretion; ko05110|Vibrio cholerae infection; ko05120|Epithelial cell signaling in Helicobacter pylori infection; ko05323|Rheumatoid arthritis	1098	OXB75475.1	OXB75475.1 hypothetical protein H355_016536 [Colinus virginianus]	sp|Q2KIB5|VA0E2_BOVIN	sp|Q2KIB5|VA0E2_BOVIN V-type proton ATPase subunit e 2 OS=Bos taurus GN=ATP6V0E2 PE=3 SV=1	9031.ENSGALP00000032616	"ATPase, H+ transporting V0 subunit e2"	_	KOG3500	_	PF05493.10|ATP_synt_H|ATP synthase subunit H|ENSGALT00000054688|m.4991:46-107
ENSGALG00000020869	3.844967853	10.09182613	-1.389825382	2.32E-06	7.07E-06	down	yes	4.763036303	3.710528752	3.061338504	9.853841118	10.94937505	9.47226223	7	11365021	11371116	-	ENSGALG00000020869	protein_coding	--	GO:0005622|intracellular; GO:0005829|cytosol; GO:0005886|plasma membrane	--	--	--	354	XP_015144956.1	XP_015144956.1 protein FAM126B isoform X2 [Gallus gallus]	sp|Q8C729|F126B_MOUSE	sp|Q8C729|F126B_MOUSE Protein FAM126B OS=Mus musculus GN=Fam126b PE=1 SV=1	9031.ENSGALP00000032826	"family with sequence similarity 126, member B"	_	KOG4688	_	PF09790.6|Hyccin|Hyccin|ENSGALT00000033467|m.5878:23-111
ENSGALG00000020876	2.672930099	0.999369595	1.410354933	3.27E-16	2.39E-15	up	yes	2.500905165	3.272000053	2.245885078	1.005438764	0.993636003	0.999034017	7	11237134	11279715	+	AOX2	protein_coding	GO:0017144|drug metabolic process; GO:0055114|oxidation-reduction process	GO:0005829|cytosol	"GO:0004031|aldehyde oxidase activity; GO:0005506|iron ion binding; GO:0009055|electron transfer activity; GO:0016614|oxidoreductase activity, acting on CH-OH group of donors; GO:0042803|protein homodimerization activity; GO:0043546|molybdopterin cofactor binding; GO:0050250|retinal oxidase activity; GO:0050660|flavin adenine dinucleotide binding; GO:0051287|NAD binding; GO:0051537|2 iron, 2 sulfur cluster binding; GO:0102797|geranial:oxygen oxidoreductase activity; GO:0102798|heptaldehyde:oxygen oxidoreductase activity"	ko:K00157|AOX	"ko00280|Valine, leucine and isoleucine degradation; ko00350|Tyrosine metabolism; ko00380|Tryptophan metabolism; ko00750|Vitamin B6 metabolism; ko00760|Nicotinate and nicotinamide metabolism; ko00830|Retinol metabolism; ko00982|Drug metabolism - cytochrome P450; ko01100|Metabolic pathways; ko01120|Microbial metabolism in diverse environments; ko04630|Jak-STAT signaling pathway"	4593	XP_025007947.1	XP_025007947.1 aldehyde oxidase 2 isoform X1 [Gallus gallus]	sp|C4NYZ3|AOXB_MACFA	sp|C4NYZ3|AOXB_MACFA Aldehyde oxidase 2 OS=Macaca fascicularis GN=AOX2 PE=2 SV=2	9031.ENSGALP00000013314	hypothetical protein LOC424072 	COG4630;COG4631	KOG0430	_	"PF02738.15|Ald_Xan_dh_C2|Molybdopterin-binding domain of aldehyde dehydrogenase|ENSGALT00000013331|m.5863:717-1243;PF00941.18|FAD_binding_5|FAD binding domain in molybdopterin dehydrogenase|ENSGALT00000013331|m.5863:244-421;PF03450.14|CO_deh_flav_C|CO dehydrogenase flavoprotein C-terminal domain|ENSGALT00000013331|m.5863:429-533;PF01315.19|Ald_Xan_dh_C|Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain|ENSGALT00000013331|m.5863:597-699;PF01799.17|Fer2_2|[2Fe-2S] binding domain|ENSGALT00000013331|m.5863:92-164;PF00111.24|Fer2|2Fe-2S iron-sulfur cluster binding domain|ENSGALT00000013331|m.5863:14-80"
ENSGALG00000020975	0.519289601	1.101488072	-1.070363252	0.004868055	0.009140747	down	yes	0.491565025	0.549205186	0.517098591	1.690526112	0.777648683	0.836289419	15	9936603	9950264	-	TMEM233	protein_coding	GO:0009607|response to biotic stimulus	GO:0016020|membrane; GO:0016021|integral component of membrane	--	--	--	2208	XP_021268426.1	XP_021268426.1 transmembrane protein 233 isoform X3 [Numida meleagris]	sp|B4DJY2|TM233_HUMAN	sp|B4DJY2|TM233_HUMAN Transmembrane protein 233 OS=Homo sapiens GN=TMEM233 PE=3 SV=1	59729.ENSTGUP00000009520	Proline-rich transmembrane protein 2 [Taeniopygia guttata]	_	_	NOG296456	PF04505.9|CD225|Interferon-induced transmembrane protein|ENSGALT00000103938|m.10961:47-111
ENSGALG00000021079	0.836547202	1.945043347	-1.207538178	1.56E-06	4.87E-06	down	yes	0.59224937	0.840460166	1.076932069	1.940285562	1.783189059	2.111655421	20	9335909	9349311	+	RGS19	protein_coding	GO:0006914|autophagy; GO:0007186|G protein-coupled receptor signaling pathway; GO:0007264|small GTPase mediated signal transduction; GO:0009968|negative regulation of signal transduction	GO:0005794|Golgi apparatus; GO:0005903|brush border; GO:0016020|membrane; GO:0030136|clathrin-coated vesicle; GO:0031410|cytoplasmic vesicle; GO:0045121|membrane raft	GO:0001965|G-protein alpha-subunit binding; GO:0005096|GTPase activator activity	ko:K16449|RGS	--	2158	XP_003212088.2	XP_003212088.2 PREDICTED: regulator of G-protein signaling 19 [Meleagris gallopavo]	sp|P49795|RGS19_HUMAN	sp|P49795|RGS19_HUMAN Regulator of G-protein signaling 19 OS=Homo sapiens GN=RGS19 PE=1 SV=1	_	_	_	_	_	PF00615.16|RGS|Regulator of G protein signaling domain|ENSGALT00000033911|m.3237:73-187
ENSGALG00000021092	0.191500903	0.481312728	-1.285855311	0.015859877	0.026888577	down	yes	0.145326093	0.350103429	0.079073186	0.546641465	0.410542418	0.486754299	9	9675721	9683849	-	ENSGALG00000021092	protein_coding	--	GO:0016021|integral component of membrane	GO:0015234|thiamine transmembrane transporter activity	"ko:K14610|SLC19A2_3,THTR"	ko04977|Vitamin digestion and absorption	2018	XP_003641805.1	XP_003641805.1 thiamine transporter 2 [Gallus gallus]	sp|Q4R877|S19A3_MACFA	sp|Q4R877|S19A3_MACFA Thiamine transporter 2 OS=Macaca fascicularis GN=SLC19A3 PE=2 SV=1	9031.ENSGALP00000004773	hypothetical protein LOC424791 	_	KOG3810	_	PF01770.15|Folate_carrier|Reduced folate carrier|ENSGALT00000004782|m.8716:11-387
ENSGALG00000021126	0.296704117	0.762993918	-1.333609528	0.017724214	0.029757076	down	yes	0.335030046	0.044662604	0.510419702	0.927972413	0.590241344	0.770767997	15	8319427	8327320	+	SLC2A11L1	protein_coding	GO:0008645|hexose transmembrane transport	GO:0005634|nucleus; GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0030054|cell junction	GO:0051119|sugar transmembrane transporter activity	--	--	1730	NP_001334639.1	"NP_001334639.1 solute carrier family 2, facilitated glucose transporter member 11-like [Gallus gallus]"	sp|Q9BYW1|GTR11_HUMAN	"sp|Q9BYW1|GTR11_HUMAN Solute carrier family 2, facilitated glucose transporter member 11 OS=Homo sapiens GN=SLC2A11 PE=2 SV=1"	9031.ENSGALP00000009742	hypothetical LOC416935	COG0477	KOG0569	_	PF00083.21|Sugar_tr|Sugar (and other) transporter|ENSGALT00000009756|m.10795:12-466;PF07690.13|MFS_1|Major Facilitator Superfamily|ENSGALT00000009756|m.10795:20-383
ENSGALG00000021158	0.25399979	1.046796719	-2.001089207	1.00E-05	2.82E-05	down	yes	0.147099635	0.323560739	0.291338995	0.829968916	1.117005462	1.193415781	11	9941798	9954055	-	SLC7A9	protein_coding	GO:0006865|amino acid transport; GO:0015804|neutral amino acid transport; GO:0015811|L-cystine transport; GO:0050900|leukocyte migration; GO:0065003|protein-containing complex assembly	GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0016324|apical plasma membrane; GO:0031526|brush border membrane	GO:0015175|neutral amino acid transmembrane transporter activity; GO:0015184|L-cystine transmembrane transporter activity; GO:0015297|antiporter activity; GO:0042605|peptide antigen binding	"ko:K13868|SLC7A9,BAT1"	ko04974|Protein digestion and absorption	1791	NP_001186062.1	"NP_001186062.1 B(0,+)-type amino acid transporter 1 [Gallus gallus]"	sp|P82251|BAT1_HUMAN	"sp|P82251|BAT1_HUMAN b(0,+)-type amino acid transporter 1 OS=Homo sapiens GN=SLC7A9 PE=1 SV=1"	9031.ENSGALP00000007521	"solute carrier family 7 (cationic amino acid transporter, y+ system), member 9"	COG0531	KOG1287	_	PF13520.3|AA_permease_2|Amino acid permease|ENSGALT00000007533|m.6622:37-437;PF00324.18|AA_permease|Amino acid permease|ENSGALT00000007533|m.6622:43-473
ENSGALG00000021171	2.721208846	6.658331189	-1.287786123	3.97E-05	0.000103379	down	yes	2.522099997	3.136024452	2.505502089	5.15907695	9.368097855	5.447818761	10	12742813	12791419	-	ENSGALG00000021171	protein_coding	GO:0001525|angiogenesis; GO:0030214|hyaluronan catabolic process; GO:1903670|regulation of sprouting angiogenesis	GO:0005887|integral component of plasma membrane; GO:0016021|integral component of membrane; GO:0070062|extracellular exosome	GO:0004415|hyalurononglucosaminidase activity; GO:0005509|calcium ion binding; GO:0045296|cadherin binding	--	--	4053	XP_015147522.1	XP_015147522.1 cell surface hyaluronidase isoform X1 [Gallus gallus]	sp|Q9UHN6|TMEM2_HUMAN	sp|Q9UHN6|TMEM2_HUMAN Cell surface hyaluronidase OS=Homo sapiens GN=TMEM2 PE=1 SV=1	9031.ENSGALP00000033447	transmembrane protein 2	_	_	NOG81482	PF10162.6|G8|G8 domain|ENSGALT00000034089|m.5612:139-250;PF15711.2|ILEI|Interleukin-like EMT inducer|ENSGALT00000034089|m.5612:273-362
ENSGALG00000021225	2.439747378	8.676286217	-1.826106507	1.49E-23	1.72E-22	down	yes	2.138084083	3.055579446	2.125578606	8.969281134	8.671028582	8.388548935	11	7727755	7733916	-	CDCA9	protein_coding	GO:0000070|mitotic sister chromatid segregation; GO:0051301|cell division	"GO:0000775|chromosome, centromeric region; GO:0005634|nucleus; GO:0032133|chromosome passenger complex; GO:0051233|spindle midzone"	--	ko:K11514|CDCA8	--	1454	NP_001263267.1	NP_001263267.1 borealin-2 [Gallus gallus]	sp|P86345|BORE2_CHICK	sp|P86345|BORE2_CHICK Borealin-2 OS=Gallus gallus GN=CDCA9 PE=2 SV=1	9031.ENSGALP00000033552	chromosomal passenger complex protein Dasra A	_	_	NOG124073	PF10444.6|Nbl1_Borealin_N|Nbl1 / Borealin N terminal|ENSGALT00000067912|m.6560:50-103;PF10512.6|Borealin|Cell division cycle-associated protein 8|ENSGALT00000067912|m.6560:195-296
ENSGALG00000021304	0.355820925	0.88732595	-1.294494536	0.000165761	0.00039333	down	yes	0.217801004	0.466791665	0.382870104	0.787744742	1.013795667	0.860437443	Z	11028611	11066332	-	RANBP3L	protein_coding	GO:0000082|G1/S transition of mitotic cell cycle; GO:0006405|RNA export from nucleus; GO:0006511|ubiquitin-dependent protein catabolic process; GO:0006606|protein import into nucleus; GO:0007051|spindle organization; GO:0043547|positive regulation of GTPase activity; GO:0045663|positive regulation of myoblast differentiation; GO:0045668|negative regulation of osteoblast differentiation; GO:0046604|positive regulation of mitotic centrosome separation; GO:1901706|mesenchymal cell differentiation involved in bone development	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005813|centrosome	GO:0008536|Ran GTPase binding; GO:0046332|SMAD binding	--	--	3098	XP_015133003.1	XP_015133003.1 ran-binding protein 3-like isoform X1 [Gallus gallus]	sp|Q6PDH4|RNB3L_MOUSE	sp|Q6PDH4|RNB3L_MOUSE Ran-binding protein 3-like OS=Mus musculus GN=Ranbp3l PE=1 SV=1	9031.ENSGALP00000033703	RAN binding protein 3-like	_	KOG0866	_	PF00638.15|Ran_BP1|RanBP1 domain|ENSGALT00000092162|m.10672:345-451
ENSGALG00000021442	0.436501231	0.168298043	1.324373289	0.000323272	0.000733814	up	yes	0.463453422	0.357230321	0.488819951	0.196676802	0.126895939	0.181321387	11	1139950	1156764	+	CARMIL2	protein_coding	"GO:0007163|establishment or maintenance of cell polarity; GO:0010592|positive regulation of lamellipodium assembly; GO:0030011|maintenance of cell polarity; GO:0030335|positive regulation of cell migration; GO:0044319|wound healing, spreading of cells; GO:0051639|actin filament network formation; GO:0061339|establishment or maintenance of monopolar cell polarity; GO:0090091|positive regulation of extracellular matrix disassembly; GO:1900029|positive regulation of ruffle assembly; GO:1902745|positive regulation of lamellipodium organization; GO:2000813|negative regulation of barbed-end actin filament capping"	GO:0001726|ruffle; GO:0005737|cytoplasm; GO:0005886|plasma membrane; GO:0015629|actin cytoskeleton; GO:0016020|membrane; GO:0030027|lamellipodium; GO:0031234|extrinsic component of cytoplasmic side of plasma membrane; GO:0031252|cell leading edge; GO:0044354|macropinosome; GO:0045111|intermediate filament cytoskeleton	GO:0005543|phospholipid binding; GO:0044877|protein-containing complex binding	"ko:K20493|LRRC16,CARMIL"	--	4434	XP_414033.4	"XP_414033.4 capping protein, Arp2/3 and myosin-I linker protein 2 isoform X1 [Gallus gallus]"	sp|Q6F5E8|CARL2_HUMAN	"sp|Q6F5E8|CARL2_HUMAN Capping protein, Arp2/3 and myosin-I linker protein 2 OS=Homo sapiens GN=CARMIL2 PE=1 SV=2"	_	_	_	_	_	PF16000.2|CARMIL_C|CARMIL C-terminus|ENSGALT00000100580|m.6261:779-1063;PF13516.3|LRR_6|Leucine Rich repeat|ENSGALT00000100580|m.6261:276-295;PF13516.3|LRR_6|Leucine Rich repeat|ENSGALT00000100580|m.6261:569-592;PF00560.30|LRR_1|Leucine Rich Repeat|ENSGALT00000100580|m.6261:336-348
ENSGALG00000021542	1.349822955	0.536912672	1.314036434	0.000485421	0.001073648	up	yes	1.871920271	1.04207845	1.135470144	0.573726934	0.520978329	0.516032753	13	11057186	11060853	+	SNCB	protein_coding	--	--	--	--	--	1247	XP_009891914.1	XP_009891914.1 PREDICTED: beta-synuclein [Charadrius vociferus]	_	_	_	_	_	_	_	PF01387.14|Synuclein|Synuclein|ENSGALT00000086972|m.8716:42-165
ENSGALG00000021567	0.03835244	0.36605038	-2.959265364	1.34E-05	3.70E-05	down	yes	0.035022326	0	0.080034994	0.4215547	0.311652041	0.3649444	21	6118469	6146506	-	EPHA8	protein_coding	GO:0006929|substrate-dependent cell migration; GO:0007155|cell adhesion; GO:0007411|axon guidance; GO:0016322|neuron remodeling; GO:0030155|regulation of cell adhesion; GO:0031175|neuron projection development; GO:0033628|regulation of cell adhesion mediated by integrin; GO:0043410|positive regulation of MAPK cascade; GO:0043552|positive regulation of phosphatidylinositol 3-kinase activity; GO:0046777|protein autophosphorylation; GO:0048013|ephrin receptor signaling pathway; GO:0071372|cellular response to follicle-stimulating hormone stimulus	GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0031901|early endosome membrane; GO:0043005|neuron projection	GO:0005004|GPI-linked ephrin receptor activity; GO:0005524|ATP binding	"ko:K05109|EPHA8,EEK"	ko04360|Axon guidance	3009	XP_015152704.1	XP_015152704.1 ephrin type-A receptor 8 [Gallus gallus]	sp|P29322|EPHA8_HUMAN	sp|P29322|EPHA8_HUMAN Ephrin type-A receptor 8 OS=Homo sapiens GN=EPHA8 PE=1 SV=2	_	_	_	_	_	PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000007554|m.4307:638-894;PF01404.16|Ephrin_lbd|Ephrin receptor ligand binding domain|ENSGALT00000007554|m.4307:33-204;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000007554|m.4307:640-892;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000007554|m.4307:330-418;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000007554|m.4307:446-524;PF00536.27|SAM_1|SAM domain (Sterile alpha motif)|ENSGALT00000007554|m.4307:927-989;PF14575.3|EphA2_TM|Ephrin type-A receptor 2 transmembrane domain|ENSGALT00000007554|m.4307:547-635;PF07647.14|SAM_2|SAM domain (Sterile alpha motif)|ENSGALT00000007554|m.4307:931-989
ENSGALG00000021570	9.230875634	3.714471595	1.310993804	3.83E-20	3.63E-19	up	yes	8.861683167	9.031126511	9.799817224	3.616444035	3.910720443	3.616250306	17	9108573	9110112	-	ZBTB6	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated"	GO:0005634|nucleus; GO:0005739|mitochondrion	GO:0003677|DNA binding; GO:0046872|metal ion binding	ko:K10493|ZBTB6	--	1540	NP_001264570.2	NP_001264570.2 zinc finger and BTB domain-containing protein 6 [Gallus gallus]	sp|Q15916|ZBTB6_HUMAN	sp|Q15916|ZBTB6_HUMAN Zinc finger and BTB domain-containing protein 6 OS=Homo sapiens GN=ZBTB6 PE=1 SV=1	9031.ENSGALP00000001874	zinc finger and BTB domain containing 6	COG5048	KOG1721	_	"PF00651.28|BTB|BTB/POZ domain|ENSGALT00000001876|m.12364:23-125;PF00096.23|zf-C2H2|Zinc finger, C2H2 type|ENSGALT00000001876|m.12364:328-349;PF13894.3|zf-C2H2_4|C2H2-type zinc finger|ENSGALT00000001876|m.12364:327-349;PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000001876|m.12364:355-375"
ENSGALG00000021572	6.975961527	18.92395073	-1.43844487	1.14E-72	7.87E-71	down	yes	7.422814383	6.914261752	6.590808445	18.2011889	20.47294047	18.09772281	19	6233052	6271407	-	SSH2	protein_coding	GO:0006470|protein dephosphorylation; GO:0008064|regulation of actin polymerization or depolymerization; GO:0010591|regulation of lamellipodium assembly; GO:0030036|actin cytoskeleton organization; GO:0050770|regulation of axonogenesis	GO:0005615|extracellular space; GO:0005737|cytoplasm; GO:0005856|cytoskeleton	GO:0003779|actin binding; GO:0004721|phosphoprotein phosphatase activity; GO:0004725|protein tyrosine phosphatase activity; GO:0008138|protein tyrosine/serine/threonine phosphatase activity	ko:K05766|SSH	ko04360|Axon guidance; ko04810|Regulation of actin cytoskeleton	6772	XP_415832.5	XP_415832.5 protein phosphatase Slingshot homolog 2 isoform X1 [Gallus gallus]	sp|Q76I76|SSH2_HUMAN	sp|Q76I76|SSH2_HUMAN Protein phosphatase Slingshot homolog 2 OS=Homo sapiens GN=SSH2 PE=1 SV=1	9031.ENSGALP00000034265	slingshot homolog 2 (Drosophila)	COG2453	KOG1716	_	"PF00782.17|DSPc|Dual specificity phosphatase, catalytic domain|ENSGALT00000034909|m.14004:369-497;PF08766.8|DEK_C|DEK C terminal domain|ENSGALT00000034909|m.14004:304-356"
ENSGALG00000021688	9.124866073	4.294115984	1.085666622	9.01E-15	5.89E-14	up	yes	8.215454719	9.482902755	9.676240744	4.505031776	4.214802761	4.162513416	28	985592	989803	+	CD320	protein_coding	--	GO:0016021|integral component of membrane	--	--	--	1583	XP_025000034.1	XP_025000034.1 CD320 antigen isoform X1 [Gallus gallus]	sp|P98162|RSVR_COTJA	sp|P98162|RSVR_COTJA Subgroup A Rous sarcoma virus receptor pg950 OS=Coturnix japonica PE=1 SV=1	9031.ENSGALP00000034553	Tva receptor 	_	_	NOG285369	PF00057.15|Ldl_recept_a|Low-density lipoprotein receptor domain class A|ENSGALT00000048591|m.9590:33-73
ENSGALG00000021848	0.500141725	1.389312908	-1.455748599	0.001852506	0.003739989	down	yes	0.771089109	0.376908803	0.352427262	1.64358137	1.280844282	1.243513073	Z	9136599	9137711	+	ENSGALG00000021848	protein_coding	GO:0019731|antibacterial humoral response	GO:0005576|extracellular region	GO:0009374|biotin binding	--	--	1025	XP_015132977.1	XP_015132977.1 avidin isoform X1 [Gallus gallus]	sp|P02701|AVID_CHICK	sp|P02701|AVID_CHICK Avidin OS=Gallus gallus GN=AVD PE=1 SV=3	_	_	_	_	_	PF01382.14|Avidin|Avidin family|ENSGALT00000103893|m.10558:27-95
ENSGALG00000021855	0.254714625	0.630439107	-1.274623501	0.006316794	0.011592623	down	yes	0.219851554	0.35821189	0.186080432	0.505369112	0.685942723	0.700005487	9	17337013	17344782	+	ENSGALG00000021855	protein_coding	GO:0001947|heart looping; GO:0003341|cilium movement; GO:0003356|regulation of cilium beat frequency; GO:0030317|flagellated sperm motility; GO:0030324|lung development; GO:0035469|determination of pancreatic left/right asymmetry; GO:0036159|inner dynein arm assembly; GO:0044458|motile cilium assembly; GO:0060285|cilium-dependent cell motility; GO:0060287|epithelial cilium movement involved in determination of left/right asymmetry; GO:0070286|axonemal dynein complex assembly; GO:0071907|determination of digestive tract left/right asymmetry; GO:0071910|determination of liver left/right asymmetry	GO:0005737|cytoplasm; GO:0005930|axoneme	--	--	--	2157	XP_422777.4	XP_422777.4 LOW QUALITY PROTEIN: coiled-coil domain-containing protein 39 [Gallus gallus]	sp|Q9UFE4|CCD39_HUMAN	sp|Q9UFE4|CCD39_HUMAN Coiled-coil domain-containing protein 39 OS=Homo sapiens GN=CCDC39 PE=2 SV=3	_	_	_	_	_	_
ENSGALG00000022704	1.160254586	0.303452274	1.900504717	0.000178946	0.000422554	up	yes	1.260105762	1.402975416	0.81768258	0.1579955	0.387618951	0.364742371	1	197389587	197391246	+	ENSGALG00000022704	protein_coding	GO:0007608|sensory perception of smell; GO:0042391|regulation of membrane potential; GO:0050896|response to stimulus	GO:0000139|Golgi membrane; GO:0005887|integral component of plasma membrane; GO:0030660|Golgi-associated vesicle membrane; GO:0060170|ciliary membrane	GO:0005249|voltage-gated potassium channel activity; GO:0030552|cAMP binding	ko:K04951|CNGA4	ko04024|cAMP signaling pathway; ko04740|Olfactory transduction	1129	XP_015136423.1	XP_015136423.1 cyclic nucleotide-gated cation channel alpha-4 isoform X2 [Gallus gallus]	sp|Q8IV77|CNGA4_HUMAN	sp|Q8IV77|CNGA4_HUMAN Cyclic nucleotide-gated cation channel alpha-4 OS=Homo sapiens GN=CNGA4 PE=1 SV=3	9031.ENSGALP00000035597	cyclic nucleotide gated channel alpha 4	_	KOG0500	_	PF16526.2|CLZ|C-terminal leucine zipper domain of cyclic nucleotide-gated channels|ENSGALT00000036377|m.5013:90-161;PF00027.26|cNMP_binding|Cyclic nucleotide-binding domain|ENSGALT00000036377|m.5013:1-81
ENSGALG00000022871	26.12255624	7.488245279	1.801223329	2.18E-73	1.52E-71	up	yes	26.85919395	26.23931932	25.26915544	6.611236405	8.679894171	7.173605262	1	88748622	88761403	+	HHLA2	protein_coding	GO:0001819|positive regulation of cytokine production; GO:0031295|T cell costimulation; GO:0042104|positive regulation of activated T cell proliferation	GO:0016021|integral component of membrane	--	--	--	2821	XP_015152975.1	XP_015152975.1 HERV-H LTR-associating protein 2 isoform X2 [Gallus gallus]	sp|Q9UM44|HHLA2_HUMAN	sp|Q9UM44|HHLA2_HUMAN HERV-H LTR-associating protein 2 OS=Homo sapiens GN=HHLA2 PE=1 SV=1	9031.ENSGALP00000036110	annotation not avaliable	_	_	NOG68246	PF07686.14|V-set|Immunoglobulin V-set domain|ENSGALT00000094520|m.2801:27-117;PF07686.14|V-set|Immunoglobulin V-set domain|ENSGALT00000094520|m.2801:215-311;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000094520|m.2801:26-118;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000094520|m.2801:214-300;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000094520|m.2801:35-126
ENSGALG00000022909	28.002529	66.01249509	-1.236885424	3.17E-70	2.07E-68	down	yes	27.25158498	28.89424412	27.86175791	61.53689382	70.5886497	65.91194176	2	84613361	84766062	-	PTPN3	protein_coding	GO:0006470|protein dephosphorylation; GO:0042059|negative regulation of epidermal growth factor receptor signaling pathway; GO:0045930|negative regulation of mitotic cell cycle; GO:0051045|negative regulation of membrane protein ectodomain proteolysis; GO:0097421|liver regeneration; GO:0098902|regulation of membrane depolarization during action potential; GO:2000649|regulation of sodium ion transmembrane transporter activity	GO:0005737|cytoplasm; GO:0005856|cytoskeleton; GO:0005886|plasma membrane; GO:0009898|cytoplasmic side of plasma membrane	GO:0001784|phosphotyrosine residue binding; GO:0004725|protein tyrosine phosphatase activity; GO:0008092|cytoskeletal protein binding; GO:0017080|sodium channel regulator activity; GO:0051117|ATPase binding	"ko:K18027|PTPN3,PTPH1"	--	2919	XP_419047.4	XP_419047.4 tyrosine-protein phosphatase non-receptor type 3 isoform X2 [Gallus gallus]	sp|P26045|PTN3_HUMAN	sp|P26045|PTN3_HUMAN Tyrosine-protein phosphatase non-receptor type 3 OS=Homo sapiens GN=PTPN3 PE=1 SV=2	_	_	_	_	_	PF00102.24|Y_phosphatase|Protein-tyrosine phosphatase|ENSGALT00000030996|m.1262:729-958;PF09380.7|FERM_C|FERM C-terminal PH-like domain|ENSGALT00000030996|m.1262:276-362;PF00595.21|PDZ|PDZ domain (Also known as DHR or GLGF)|ENSGALT00000030996|m.1262:571-654;PF00373.15|FERM_M|FERM central domain|ENSGALT00000030996|m.1262:161-270;PF09379.7|FERM_N|FERM N-terminal domain|ENSGALT00000030996|m.1262:81-144
ENSGALG00000022920	13.55192434	6.625434009	1.031299164	3.93E-21	3.94E-20	up	yes	14.50120428	13.91864147	12.23592726	7.300774604	6.408955885	6.166571537	4	89706420	89714666	-	SMYD5	protein_coding	--	--	GO:0008168|methyltransferase activity; GO:0046872|metal ion binding	--	--	2598	NP_001012912.1	NP_001012912.1 SET and MYND domain-containing protein 5 [Gallus gallus]	sp|Q5ZIZ2|SMYD5_CHICK	sp|Q5ZIZ2|SMYD5_CHICK SET and MYND domain-containing protein 5 OS=Gallus gallus GN=SMYD5 PE=2 SV=1	9031.ENSGALP00000025878	SMYD family member 5 	_	KOG2084	_	PF00856.25|SET|SET domain|ENSGALT00000072661|m.1701:45-363
ENSGALG00000023036	0.469808725	0.226439228	1.020989974	0.004437595	0.008396407	up	yes	0.389111684	0.57059405	0.44972044	0.191786858	0.222878429	0.264652397	Z	81787829	81793027	+	ENSGALG00000023036	protein_coding	--	--	--	--	--	3927	XP_015136283.1	XP_015136283.1 FERM and PDZ domain-containing protein 1 isoform X2 [Gallus gallus]	_	_	9031.ENSGALP00000036695	annotation not avaliable	_	KOG3552	_	_
ENSGALG00000023070	6.591070318	1.669220131	1.974908599	4.82E-21	4.79E-20	up	yes	6.207645841	7.260648538	6.304916575	2.126513064	1.286005412	1.595141918	5	45754128	45759449	-	SPIA1	protein_coding	GO:0006953|acute-phase response	GO:0005615|extracellular space	GO:0004867|serine-type endopeptidase inhibitor activity	ko:K04525|SERPINA	--	1426	NP_001264422.1	NP_001264422.1 alpha-1-antitrypsin precursor [Gallus gallus]	sp|P38029|A1AT2_HORSE	sp|P38029|A1AT2_HORSE Alpha-1-antiproteinase 2 OS=Equus caballus PE=1 SV=2	9031.ENSGALP00000036785	"serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1"	COG4826	KOG2392	_	PF00079.17|Serpin|Serpin (serine protease inhibitor)|ENSGALT00000037577|m.3792:55-420
ENSGALG00000023122	4.432046768	12.8846109	-1.537471753	7.46E-19	6.56E-18	down	yes	3.593677967	4.486430589	5.216031748	13.51755456	11.27425914	13.86201901	4	51790372	51792467	-	SULT1B	protein_coding	GO:0006805|xenobiotic metabolic process; GO:0008202|steroid metabolic process; GO:0042403|thyroid hormone metabolic process; GO:0051923|sulfation	GO:0005737|cytoplasm	GO:0008146|sulfotransferase activity	ko:K01025|E2.8.2.-	--	1085	NP_001299607.1	"NP_001299607.1 sulfotransferase family, cytosolic, 1B [Gallus gallus]"	sp|Q8JG30|ST1B1_CHICK	sp|Q8JG30|ST1B1_CHICK Sulfotransferase family cytosolic 1B member 1 OS=Gallus gallus GN=SULT1B1 PE=2 SV=1	_	_	_	_	_	PF00685.24|Sulfotransfer_1|Sulfotransferase domain|ENSGALT00000019279|m.737:84-334
ENSGALG00000023131	7.726347718	2.340809677	1.718494897	4.52E-31	7.54E-30	up	yes	7.708511184	7.85183049	7.618701482	2.716027167	2.054970075	2.251431789	1	51181690	51185095	-	PDXP	protein_coding	GO:0006470|protein dephosphorylation; GO:0007088|regulation of mitotic nuclear division; GO:0030836|positive regulation of actin filament depolymerization; GO:0031247|actin rod assembly; GO:0032361|pyridoxal phosphate catabolic process; GO:0032465|regulation of cytokinesis; GO:0071318|cellular response to ATP	GO:0005829|cytosol; GO:0005856|cytoskeleton; GO:0031258|lamellipodium membrane; GO:0032587|ruffle membrane; GO:0070062|extracellular exosome	"GO:0000287|magnesium ion binding; GO:0004647|phosphoserine phosphatase activity; GO:0004721|phosphoprotein phosphatase activity; GO:0031072|heat shock protein binding; GO:0033883|pyridoxal phosphatase activity; GO:0098519|nucleotide phosphatase activity, acting on free nucleotides"	ko:K07758|PDXP	ko00750|Vitamin B6 metabolism; ko01100|Metabolic pathways	2160	XP_003640432.2	XP_003640432.2 pyridoxal phosphate phosphatase [Gallus gallus]	sp|Q96GD0|PLPP_HUMAN	sp|Q96GD0|PLPP_HUMAN Pyridoxal phosphate phosphatase OS=Homo sapiens GN=PDXP PE=1 SV=2	9031.ENSGALP00000020277	"PREDICTED: Gallus gallus similar to Pyridoxal (pyridoxine, vitamin B6) phosphatase (LOC77120 [...] "	COG0647	KOG2882	_	PF13344.3|Hydrolase_6|Haloacid dehalogenase-like hydrolase|ENSGALT00000037821|m.1430:35-144;PF13242.3|Hydrolase_like|HAD-hyrolase-like|ENSGALT00000037821|m.1430:225-306;PF00702.23|Hydrolase|haloacid dehalogenase-like hydrolase|ENSGALT00000037821|m.1430:35-265
ENSGALG00000023195	1.149132225	2.410726597	-1.062395	7.79E-07	2.53E-06	down	yes	1.269227886	1.169895871	1.008272917	2.26432428	2.882770657	2.085084854	2	24442691	24446535	+	DLX6	protein_coding	"GO:0006355|regulation of transcription, DNA-templated; GO:0033339|pectoral fin development; GO:0035141|medial fin morphogenesis"	GO:0005634|nucleus	GO:0043565|sequence-specific DNA binding	ko:K09314|DLX1_4_6	--	1988	NP_001074359.1	NP_001074359.1 homeobox protein DLX-6 [Gallus gallus]	sp|Q98877|DLX6A_DANRE	sp|Q98877|DLX6A_DANRE Homeobox protein Dlx6a OS=Danio rerio GN=dlx6a PE=2 SV=1	9031.ENSGALP00000037212	Homeodomain transcription factor DLX6 	_	KOG0850	_	PF00046.26|Homeobox|Homeobox domain|ENSGALT00000102858|m.61:142-185
ENSGALG00000023348	0.949868551	0.408550321	1.197435768	0.002680957	0.00526475	up	yes	0.994171493	0.971903202	0.883530959	0.361490612	0.432510311	0.431650039	8	21383947	21385536	+	HPDL	protein_coding	GO:0009072|aromatic amino acid family metabolic process	--	"GO:0016701|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen; GO:0046872|metal ion binding; GO:0051213|dioxygenase activity"	--	--	1590	XP_015146767.1	XP_015146767.1 4-hydroxyphenylpyruvate dioxygenase-like protein [Gallus gallus]	sp|Q8K248|HPDL_MOUSE	sp|Q8K248|HPDL_MOUSE 4-hydroxyphenylpyruvate dioxygenase-like protein OS=Mus musculus GN=Hpdl PE=2 SV=1	9031.ENSGALP00000037663	4-hydroxyphenylpyruvate dioxygenase-like	COG3185	KOG0638	_	PF00903.22|Glyoxalase|Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily|ENSGALT00000038457|m.7848:172-297
ENSGALG00000023396	0.859535711	0.333053772	1.341810552	0.000771176	0.001650977	up	yes	0.96000328	0.687878074	0.93072578	0.221586235	0.517742439	0.259832641	15	7425953	7432354	+	ASPHD2	protein_coding	GO:0018193|peptidyl-amino acid modification	GO:0016020|membrane; GO:0016021|integral component of membrane	GO:0046872|metal ion binding; GO:0051213|dioxygenase activity	--	--	2415	XP_015130976.1	XP_015130976.1 aspartate beta-hydroxylase domain-containing protein 2 [Gallus gallus]	sp|Q6ICH7|ASPH2_HUMAN	sp|Q6ICH7|ASPH2_HUMAN Aspartate beta-hydroxylase domain-containing protein 2 OS=Homo sapiens GN=ASPHD2 PE=2 SV=1	9031.ENSGALP00000037834	aspartate beta-hydroxylase domain containing 2	COG3555	KOG3696	_	PF05118.12|Asp_Arg_Hydrox|Aspartyl/Asparaginyl beta-hydroxylase|ENSGALT00000038626|m.10714:166-325
ENSGALG00000023407	10.04982107	4.437940757	1.177395168	8.28E-21	8.11E-20	up	yes	8.502518645	11.44908004	10.19786454	4.735806495	4.219560709	4.358455068	17	10555811	10564313	+	ZBTB34	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated"	GO:0005654|nucleoplasm	GO:0003677|DNA binding; GO:0046872|metal ion binding	ko:K10508|ZBTB34	--	2578	XP_009091560.2	XP_009091560.2 PREDICTED: zinc finger and BTB domain-containing protein 34 [Serinus canaria]	sp|Q8NCN2|ZBT34_HUMAN	sp|Q8NCN2|ZBT34_HUMAN Zinc finger and BTB domain-containing protein 34 OS=Homo sapiens GN=ZBTB34 PE=1 SV=4	9031.ENSGALP00000037868	zinc finger and BTB domain containing 34 	_	KOG1721	_	PF00651.28|BTB|BTB/POZ domain|ENSGALT00000038660|m.12451:55-156;PF13894.3|zf-C2H2_4|C2H2-type zinc finger|ENSGALT00000038660|m.12451:406-427;PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000038660|m.12451:433-455;PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000038660|m.12451:461-481;PF11822.5|DUF3342|Domain of unknown function (DUF3342)|ENSGALT00000038660|m.12451:72-151
ENSGALG00000023443	33.59898829	14.35887493	1.22590001	3.16E-40	8.03E-39	up	yes	31.20254439	34.00266782	35.59175268	14.49482331	15.68491383	12.89688765	Z	19017539	19020278	-	SMIM15	protein_coding	--	GO:0016021|integral component of membrane	--	--	--	1969	POI28518.1	"POI28518.1 hypothetical protein CIB84_007731, partial [Bambusicola thoracicus]"	sp|Q5F409|SIM15_CHICK	sp|Q5F409|SIM15_CHICK Small integral membrane protein 15 OS=Gallus gallus GN=SMIM15 PE=3 SV=1	9031.ENSGALP00000037976	UPF0542 protein C5orf43 homolog 	_	_	NOG39758	PF15086.3|UPF0542|Uncharacterised protein family UPF0542|ENSGALT00000087303|m.10846:34-100
ENSGALG00000023510	93.01828305	45.65878694	1.026460931	5.16E-58	2.37E-56	up	yes	89.50747157	96.81013458	92.73724299	45.42807477	47.61555386	43.93273219	15	6557193	6561304	-	ERP29	protein_coding	GO:0006457|protein folding; GO:0006886|intracellular protein transport; GO:0009306|protein secretion	GO:0005783|endoplasmic reticulum; GO:0005788|endoplasmic reticulum lumen	--	ko:K09586|ERP29	ko04141|Protein processing in endoplasmic reticulum	1955	NP_001263253.1	NP_001263253.1 endoplasmic reticulum resident protein 29 precursor [Gallus gallus]	sp|P81628|ERP29_CHICK	sp|P81628|ERP29_CHICK Endoplasmic reticulum resident protein 29 (Fragment) OS=Gallus gallus GN=ERP29 PE=1 SV=2	9031.ENSGALP00000038209	Endoplasmic reticulum protein ERp29 Fragment ; Does not seem to be a disulfide isomerase. Pl [...] 	_	_	NOG82861	"PF07912.10|ERp29_N|ERp29, N-terminal domain|ENSGALT00000038999|m.10593:24-146;PF07749.9|ERp29|Endoplasmic reticulum protein ERp29, C-terminal domain|ENSGALT00000038999|m.10593:147-242"
ENSGALG00000023521	11.39579783	22.95985948	-1.009974666	3.56E-17	2.78E-16	down	yes	13.18263952	9.549767983	11.45498597	23.70935832	22.69670383	22.4735163	6	27190992	27192326	+	ADRA2A	protein_coding	GO:0001819|positive regulation of cytokine production; GO:0006940|regulation of smooth muscle contraction; GO:0007194|negative regulation of adenylate cyclase activity; GO:0007267|cell-cell signaling; GO:0019229|regulation of vasoconstriction; GO:0030168|platelet activation; GO:0030335|positive regulation of cell migration; GO:0032148|activation of protein kinase B activity; GO:0032870|cellular response to hormone stimulus; GO:0042593|glucose homeostasis; GO:0043268|positive regulation of potassium ion transport; GO:0050995|negative regulation of lipid catabolic process; GO:0051044|positive regulation of membrane protein ectodomain proteolysis; GO:0051926|negative regulation of calcium ion transport; GO:0061179|negative regulation of insulin secretion involved in cellular response to glucose stimulus; GO:0071878|negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway; GO:0071880|adenylate cyclase-activating adrenergic receptor signaling pathway; GO:0071881|adenylate cyclase-inhibiting adrenergic receptor signaling pathway; GO:0071882|phospholipase C-activating adrenergic receptor signaling pathway; GO:0071883|activation of MAPK activity by adrenergic receptor signaling pathway; GO:0090303|positive regulation of wound healing; GO:1901020|negative regulation of calcium ion transmembrane transporter activity	GO:0005737|cytoplasm; GO:0005887|integral component of plasma membrane; GO:0043235|receptor complex	GO:0004938|alpha2-adrenergic receptor activity; GO:0019901|protein kinase binding; GO:0031692|alpha-1B adrenergic receptor binding; GO:0031696|alpha-2C adrenergic receptor binding; GO:0031996|thioesterase binding; GO:0032795|heterotrimeric G-protein binding; GO:0042803|protein homodimerization activity; GO:0046982|protein heterodimerization activity; GO:0051379|epinephrine binding; GO:0051380|norepinephrine binding	ko:K04138|ADRA2A	ko04022|cGMP-PKG signaling pathway; ko04080|Neuroactive ligand-receptor interaction	1335	XP_004942333.2	XP_004942333.2 alpha-2A adrenergic receptor [Gallus gallus]	sp|P18871|ADA2A_PIG	sp|P18871|ADA2A_PIG Alpha-2A adrenergic receptor OS=Sus scrofa GN=ADRA2A PE=1 SV=1	_	_	_	_	_	PF00001.18|7tm_1|7 transmembrane receptor (rhodopsin family)|ENSGALT00000039041|m.5288:74-420;PF10320.6|7TM_GPCR_Srsx|Serpentine type 7TM GPCR chemoreceptor Srsx|ENSGALT00000039041|m.5288:69-240;PF10328.6|7TM_GPCR_Srx|Serpentine type 7TM GPCR chemoreceptor Srx|ENSGALT00000039041|m.5288:67-198
ENSGALG00000023541	2.984661558	7.322843928	-1.291979868	2.75E-15	1.87E-14	down	yes	3.404654988	2.852909708	2.696419977	7.1452407	6.486848115	8.336442968	18	4429920	4435069	-	ENSGALG00000023541	protein_coding	GO:0001568|blood vessel development; GO:0006670|sphingosine metabolic process; GO:0006954|inflammatory response; GO:0007420|brain development; GO:0008284|positive regulation of cell population proliferation; GO:0010800|positive regulation of peptidyl-threonine phosphorylation; GO:0010803|regulation of tumor necrosis factor-mediated signaling pathway; GO:0019722|calcium-mediated signaling; GO:0030307|positive regulation of cell growth; GO:0030335|positive regulation of cell migration; GO:0031398|positive regulation of protein ubiquitination; GO:0032651|regulation of interleukin-1 beta production; GO:0043066|negative regulation of apoptotic process; GO:0045766|positive regulation of angiogenesis; GO:0045931|positive regulation of mitotic cell cycle; GO:0045987|positive regulation of smooth muscle contraction; GO:0046512|sphingosine biosynthetic process; GO:0048146|positive regulation of fibroblast proliferation; GO:0051092|positive regulation of NF-kappaB transcription factor activity; GO:1901224|positive regulation of NIK/NF-kappaB signaling	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005886|plasma membrane	GO:0000287|magnesium ion binding; GO:0003677|DNA binding; GO:0003951|NAD+ kinase activity; GO:0005516|calmodulin binding; GO:0005524|ATP binding; GO:0008481|sphinganine kinase activity; GO:0017050|D-erythro-sphingosine kinase activity; GO:0038036|sphingosine-1-phosphate receptor activity; GO:0051721|protein phosphatase 2A binding	ko:K04718|SPHK	ko00600|Sphingolipid metabolism; ko01100|Metabolic pathways; ko04020|Calcium signaling pathway; ko04071|Sphingolipid signaling pathway; ko04072|Phospholipase D signaling pathway; ko04370|VEGF signaling pathway; ko04371|Apelin signaling pathway; ko04666|Fc gamma R-mediated phagocytosis; ko05152|Tuberculosis	1950	XP_015150786.1	XP_015150786.1 sphingosine kinase 1 [Gallus gallus]	sp|Q8CI15|SPHK1_MOUSE	sp|Q8CI15|SPHK1_MOUSE Sphingosine kinase 1 OS=Mus musculus GN=Sphk1 PE=1 SV=1	_	_	_	_	_	PF00781.21|DAGK_cat|Diacylglycerol kinase catalytic domain|ENSGALT00000082303|m.12676:285-420
ENSGALG00000023554	3.499012341	1.350660329	1.36675806	1.84E-10	8.53E-10	up	yes	3.733116643	3.57288753	3.191032852	1.2326991	1.228483242	1.590798644	19	8290811	8292659	+	PIGW	protein_coding	GO:0006506|GPI anchor biosynthetic process; GO:0072659|protein localization to plasma membrane	GO:0005789|endoplasmic reticulum membrane; GO:0016021|integral component of membrane	"GO:0016746|transferase activity, transferring acyl groups"	ko:K05283|PIGW	ko00563|Glycosylphosphatidylinositol (GPI)-anchor biosynthesis; ko01100|Metabolic pathways	1849	POI32271.1	POI32271.1 hypothetical protein CIB84_003979 [Bambusicola thoracicus]	sp|Q1LZA4|PIGW_BOVIN	sp|Q1LZA4|PIGW_BOVIN Phosphatidylinositol-glycan biosynthesis class W protein OS=Bos taurus GN=PIGW PE=2 SV=1	9031.ENSGALP00000038373	"phosphatidylinositol glycan anchor biosynthesis, class W"	COG5062	KOG0411	_	PF06423.9|GWT1|GWT1|ENSGALT00000039163|m.14150:302-456
ENSGALG00000023571	11.70678908	3.82019563	1.613087276	2.70E-10	1.23E-09	up	yes	10.94549194	12.31781667	11.85705864	3.987868325	2.622509269	4.850209297	9	22301097	22314263	+	TRIM59	protein_coding	GO:0060271|cilium assembly	GO:0005783|endoplasmic reticulum; GO:0005789|endoplasmic reticulum membrane; GO:0005813|centrosome; GO:0005929|cilium; GO:0016021|integral component of membrane; GO:0030992|intraciliary transport particle B	GO:0008270|zinc ion binding	ko:K12028|TRIM59	--	3274	XP_015147162.1	XP_015147162.1 tripartite motif-containing protein 59 isoform X1 [Gallus gallus]	sp|Q5ZMD4|TRI59_CHICK	sp|Q5ZMD4|TRI59_CHICK Tripartite motif-containing protein 59 OS=Gallus gallus GN=TRIM59 PE=2 SV=1	9031.ENSGALP00000038403	Tripartite motif-containing protein 59 	_	KOG2177	_	"PF13445.3|zf-RING_UBOX|RING-type zinc-finger|ENSGALT00000039192|m.9309:49-96;PF00643.21|zf-B_box|B-box zinc finger|ENSGALT00000039192|m.9309:133-172;PF13923.3|zf-C3HC4_2|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000039192|m.9309:49-76;PF00097.22|zf-C3HC4|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000039192|m.9309:49-98;PF13639.3|zf-RING_2|Ring finger domain|ENSGALT00000039192|m.9309:48-99"
ENSGALG00000023576	24.54297349	99.92839767	-2.025141335	4.13E-114	7.45E-112	down	yes	23.14117552	24.28088707	26.20685787	112.3315663	99.98541851	87.46820818	1	19335370	19339085	-	PIM3	protein_coding	GO:0043066|negative regulation of apoptotic process	GO:0005737|cytoplasm	GO:0004674|protein serine/threonine kinase activity; GO:0005524|ATP binding	ko:K08807|PIM3	--	1965	XP_003640390.1	XP_003640390.1 serine/threonine-protein kinase pim-3 [Gallus gallus]	sp|Q9PU85|PIM3_COTJA	sp|Q9PU85|PIM3_COTJA Serine/threonine-protein kinase pim-3 OS=Coturnix japonica GN=PIM3 PE=2 SV=1	28377.ENSACAP00000008806	pim-3 oncogene	COG0515	KOG0583	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000039200|m.571:40-291;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000039200|m.571:42-286;PF14531.3|Kinase-like|Kinase-like|ENSGALT00000039200|m.571:151-270
ENSGALG00000023691	6.087630683	2.952363618	1.041500037	4.82E-11	2.34E-10	up	yes	6.804923708	6.192348045	5.265620297	3.035169633	2.818974112	3.002947108	6	23064891	23068556	-	ENTPD7	protein_coding	GO:0034656|nucleobase-containing small molecule catabolic process	GO:0016021|integral component of membrane; GO:0030666|endocytic vesicle membrane	GO:0017111|nucleoside-triphosphatase activity; GO:0046872|metal ion binding	ko:K14643|ENTPD7	--	1959	XP_427896.3	XP_427896.3 ectonucleoside triphosphate diphosphohydrolase 7 [Gallus gallus]	sp|Q9NQZ7|ENTP7_HUMAN	sp|Q9NQZ7|ENTP7_HUMAN Ectonucleoside triphosphate diphosphohydrolase 7 OS=Homo sapiens GN=ENTPD7 PE=2 SV=1	_	_	_	_	_	PF01150.14|GDA1_CD39|GDA1/CD39 (nucleoside phosphatase) family|ENSGALT00000039577|m.4993:10-464
ENSGALG00000023725	26.95398499	77.59357222	-1.525089336	1.02E-40	2.69E-39	down	yes	29.69455445	26.84676685	24.32063367	84.37351457	65.8434193	82.56378277	8	6182039	6182746	-	IER5	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0034605|cellular response to heat; GO:0042127|regulation of cell population proliferation; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:1900036|positive regulation of cellular response to heat"	GO:0000159|protein phosphatase type 2A complex; GO:0005634|nucleus; GO:0005737|cytoplasm	GO:0042802|identical protein binding	--	--	708	XP_015145976.1	XP_015145976.1 immediate early response gene 5 protein [Gallus gallus]	sp|O89113|IER5_MOUSE	sp|O89113|IER5_MOUSE Immediate early response gene 5 protein OS=Mus musculus GN=Ier5 PE=2 SV=1	9031.ENSGALP00000038885	annotation not avaliable	_	_	NOG44792	PF05760.9|IER|Immediate early response protein (IER)|ENSGALT00000039676|m.7166:1-162;PF05760.9|IER|Immediate early response protein (IER)|ENSGALT00000039676|m.7166:145-235
ENSGALG00000023742	0.231193788	0.523570801	-1.145486972	0.007318015	0.013282796	down	yes	0.254735648	0.229873721	0.208971993	0.560168831	0.441736924	0.568806649	7	6598427	6621152	+	AHR2	protein_coding	"GO:0001568|blood vessel development; GO:0006355|regulation of transcription, DNA-templated; GO:0006357|regulation of transcription by RNA polymerase II; GO:0006366|transcription by RNA polymerase II; GO:0006805|xenobiotic metabolic process; GO:0006915|apoptotic process; GO:0007049|cell cycle; GO:0009410|response to xenobiotic stimulus; GO:0009636|response to toxic substance; GO:0010468|regulation of gene expression; GO:0030888|regulation of B cell proliferation; GO:0032922|circadian regulation of gene expression; GO:0045892|negative regulation of transcription, DNA-templated; GO:0045893|positive regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005667|transcription factor complex; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0032991|protein-containing complex; GO:0034752|cytosolic aryl hydrocarbon receptor complex; GO:0034753|nuclear aryl hydrocarbon receptor complex	GO:0001094|TFIID-class transcription factor complex binding; GO:0001223|transcription coactivator binding; GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity; GO:0004879|nuclear receptor activity; GO:0008134|transcription factor binding; GO:0017025|TBP-class protein binding; GO:0035326|enhancer binding; GO:0044212|transcription regulatory region DNA binding; GO:0046982|protein heterodimerization activity; GO:0046983|protein dimerization activity; GO:0051879|Hsp90 protein binding; GO:0070888|E-box binding	--	--	2689	NP_001305937.1	NP_001305937.1 aryl hydrocarbon receptor 2 [Gallus gallus]	sp|P35869|AHR_HUMAN	sp|P35869|AHR_HUMAN Aryl hydrocarbon receptor OS=Homo sapiens GN=AHR PE=1 SV=2	9031.ENSGALP00000008817	similar to Aryl Hydrocarbon Receptor 2	_	KOG3560	_	PF08447.9|PAS_3|PAS fold|ENSGALT00000008831|m.5762:287-360;PF14598.3|PAS_11|PAS domain|ENSGALT00000008831|m.5762:268-371;PF00989.22|PAS|PAS fold|ENSGALT00000008831|m.5762:114-176;PF00010.23|HLH|Helix-loop-helix DNA-binding domain|ENSGALT00000008831|m.5762:33-74
ENSGALG00000023821	0.834623444	1.76888938	-1.074596603	0.000392263	0.000879517	down	yes	1.066831928	0.763123996	0.673914407	1.340885484	1.728876232	2.236906423	27	7642263	7646075	-	DHX58	protein_coding	GO:0009615|response to virus; GO:0016032|viral process; GO:0032480|negative regulation of type I interferon production; GO:0032481|positive regulation of type I interferon production; GO:0039534|negative regulation of MDA-5 signaling pathway; GO:0039536|negative regulation of RIG-I signaling pathway; GO:0045087|innate immune response; GO:0045088|regulation of innate immune response; GO:0045824|negative regulation of innate immune response; GO:0051607|defense response to virus; GO:1900245|positive regulation of MDA-5 signaling pathway; GO:1900246|positive regulation of RIG-I signaling pathway	GO:0005737|cytoplasm	GO:0003677|DNA binding; GO:0003725|double-stranded RNA binding; GO:0003727|single-stranded RNA binding; GO:0004386|helicase activity; GO:0005524|ATP binding; GO:0008270|zinc ion binding	"ko:K12649|DHX58,LGP2"	ko04622|RIG-I-like receptor signaling pathway	2025	NP_001305337.1	NP_001305337.1 probable ATP-dependent RNA helicase DHX58 [Gallus gallus]	sp|Q96C10|DHX58_HUMAN	sp|Q96C10|DHX58_HUMAN Probable ATP-dependent RNA helicase DHX58 OS=Homo sapiens GN=DHX58 PE=1 SV=1	_	_	_	_	_	"PF11648.5|RIG-I_C-RD|C-terminal domain of RIG-I|ENSGALT00000005325|m.9382:551-664;PF00271.28|Helicase_C|Helicase conserved C-terminal domain|ENSGALT00000005325|m.9382:365-472;PF04851.12|ResIII|Type III restriction enzyme, res subunit|ENSGALT00000005325|m.9382:2-170;PF00270.26|DEAD|DEAD/DEAH box helicase|ENSGALT00000005325|m.9382:6-169"
ENSGALG00000023881	1.299014226	0.437084369	1.549861763	2.05E-05	5.54E-05	up	yes	0.940912305	1.485890473	1.4702399	0.235948306	0.572503658	0.502801144	27	6899093	6910109	-	PLXDC1	protein_coding	GO:0001525|angiogenesis; GO:0021510|spinal cord development	GO:0005576|extracellular region; GO:0005615|extracellular space; GO:0005622|intracellular; GO:0005737|cytoplasm; GO:0005886|plasma membrane; GO:0005923|bicellular tight junction; GO:0016021|integral component of membrane; GO:0030425|dendrite; GO:0043025|neuronal cell body; GO:0043235|receptor complex	--	--	--	2184	XP_015155010.1	XP_015155010.1 plexin domain-containing protein 1 isoform X2 [Gallus gallus]	sp|Q8IUK5|PLDX1_HUMAN	sp|Q8IUK5|PLDX1_HUMAN Plexin domain-containing protein 1 OS=Homo sapiens GN=PLXDC1 PE=1 SV=2	_	_	_	_	_	PF01437.22|PSI|Plexin repeat|ENSGALT00000040133|m.9169:303-347
ENSGALG00000023886	0.76112243	0.357972213	1.067363105	0.000853541	0.00181445	up	yes	0.790013652	0.837827399	0.65552624	0.329001011	0.256653313	0.488262316	7	1828066	1959021	-	ZNF804A	protein_coding	GO:0010628|positive regulation of gene expression; GO:0010975|regulation of neuron projection development; GO:0010976|positive regulation of neuron projection development; GO:1902952|positive regulation of dendritic spine maintenance	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005886|plasma membrane; GO:0030424|axon; GO:0030426|growth cone; GO:0043025|neuronal cell body; GO:0043197|dendritic spine; GO:0043198|dendritic shaft; GO:0098793|presynapse; GO:0098794|postsynapse; GO:1901588|dendritic microtubule	GO:0003676|nucleic acid binding; GO:0046872|metal ion binding	--	--	3735	XP_421853.6	XP_421853.6 zinc finger protein 804A [Gallus gallus]	sp|Q7Z570|Z804A_HUMAN	sp|Q7Z570|Z804A_HUMAN Zinc finger protein 804A OS=Homo sapiens GN=ZNF804A PE=2 SV=3	_	_	_	_	_	PF12171.5|zf-C2H2_jaz|Zinc-finger double-stranded RNA-binding|ENSGALT00000040147|m.5617:74-101
ENSGALG00000023898	3.658860736	1.129115133	1.687418572	1.45E-30	2.35E-29	up	yes	3.26612172	3.974038994	3.736421494	1.109654242	1.240810417	1.036880742	11	1269388	1321969	-	ENSGALG00000023898	protein_coding	--	--	--	--	--	4082	XP_015134684.1	XP_015134684.1 puratrophin-1 isoform X6 [Gallus gallus]	_	_	_	_	_	_	_	_
ENSGALG00000023933	4.533809749	17.16416209	-1.918265378	0.002019864	0.004051967	down	yes	5.728931004	1.326460165	6.546038078	18.23181674	16.93365899	16.32701054	26	3140579	3141464	+	G0S2	protein_coding	GO:0007049|cell cycle; GO:0097191|extrinsic apoptotic signaling pathway; GO:2001238|positive regulation of extrinsic apoptotic signaling pathway	GO:0005739|mitochondrion	--	--	--	699	OXB54600.1	OXB54600.1 hypothetical protein ASZ78_004040 [Callipepla squamata]	sp|Q5M840|G0S2_RAT	sp|Q5M840|G0S2_RAT G0/G1 switch protein 2 OS=Rattus norvegicus GN=G0s2 PE=3 SV=1	9031.ENSGALP00000039491	G0/G1switch 2	_	_	NOG45933	PF15103.3|G0-G1_switch_2|G0/G1 switch protein 2|ENSGALT00000040292|m.8070:38-136
ENSGALG00000024049	3.341903116	1.038306479	1.67691989	0.001054307	0.002213203	up	yes	0.736470115	5.056181304	4.233057928	1.636947587	0.556063273	0.921908578	4	1567283	1571532	-	RAB33A	protein_coding	GO:0019882|antigen processing and presentation; GO:2000785|regulation of autophagosome assembly	GO:0005886|plasma membrane	GO:0003924|GTPase activity; GO:0005525|GTP binding	ko:K07919|RAB33A	--	787	XP_025006102.1	XP_025006102.1 ras-related protein Rab-33A isoform X2 [Gallus gallus]	sp|P97950|RB33A_MOUSE	sp|P97950|RB33A_MOUSE Ras-related protein Rab-33A OS=Mus musculus GN=Rab33a PE=2 SV=1	9031.ENSGALP00000039779	"RAB33A, member RAS oncogene family"	COG1100	KOG0084	_	"PF00071.19|Ras|Ras family|ENSGALT00000040577|m.15997:25-187;PF08477.10|Roc|Ras of Complex, Roc, domain of DAPkinase|ENSGALT00000040577|m.15997:25-142;PF00025.18|Arf|ADP-ribosylation factor family|ENSGALT00000040577|m.15997:21-148;PF04670.9|Gtr1_RagA|Gtr1/RagA G protein conserved region|ENSGALT00000040577|m.15997:25-110;PF01926.20|MMR_HSR1|50S ribosome-binding GTPase|ENSGALT00000040577|m.15997:25-121;PF09439.7|SRPRB|Signal recognition particle receptor beta subunit|ENSGALT00000040577|m.15997:25-107"
ENSGALG00000024083	11.61772946	40.45025509	-1.798936006	5.92E-54	2.45E-52	down	yes	9.983195405	11.36269185	13.50730112	45.57707879	36.23329444	39.54039202	22	2793540	2795001	+	TCIM	protein_coding	GO:0002264|endothelial cell activation involved in immune response; GO:0006915|apoptotic process; GO:0010739|positive regulation of protein kinase A signaling; GO:0034605|cellular response to heat; GO:0043066|negative regulation of apoptotic process; GO:0043620|regulation of DNA-templated transcription in response to stress; GO:0045746|negative regulation of Notch signaling pathway; GO:1900020|positive regulation of protein kinase C activity; GO:1901224|positive regulation of NIK/NF-kappaB signaling; GO:1902806|regulation of cell cycle G1/S phase transition; GO:1903706|regulation of hemopoiesis	GO:0005622|intracellular; GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005730|nucleolus; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0016607|nuclear speck	GO:0005112|Notch binding	--	--	1462	XP_001232955.1	XP_001232955.1 transcriptional and immune response regulator [Gallus gallus]	sp|Q9D915|TCIM_MOUSE	sp|Q9D915|TCIM_MOUSE Transcriptional and immune response regulator OS=Mus musculus GN=Tcim PE=1 SV=1	9031.ENSGALP00000039860	chromosome 8 open reading frame 4	_	_	NOG41380	PF15063.3|TC1|Thyroid cancer protein 1|ENSGALT00000040657|m.4785:11-85
ENSGALG00000024318	2.206384823	1.036689349	1.08237507	0.000447203	0.000994947	up	yes	2.098167967	1.736879037	2.784107464	1.400232721	0.803049447	0.906785878	23	2822852	2824408	-	TMEM200B	protein_coding	--	GO:0016021|integral component of membrane	--	--	--	1557	XP_425776.2	XP_425776.2 transmembrane protein 200B [Gallus gallus]	sp|Q69YZ2|T200B_HUMAN	sp|Q69YZ2|T200B_HUMAN Transmembrane protein 200B OS=Homo sapiens GN=TMEM200B PE=2 SV=1	9031.ENSGALP00000040299	annotation not avaliable	_	KOG4823	_	PF10177.6|DUF2371|Uncharacterised conserved protein (DUF2371)|ENSGALT00000041093|m.5423:146-265
ENSGALG00000025751	1.118163124	4.424953234	-1.974943205	1.53E-24	1.86E-23	down	yes	1.163729575	1.074459859	1.116299939	4.920463078	4.440567842	3.913828782	28	1567936	1574937	-	NMRK2	protein_coding	GO:0009435|NAD biosynthetic process; GO:0019674|NAD metabolic process; GO:0045662|negative regulation of myoblast differentiation	GO:0005654|nucleoplasm; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0043231|intracellular membrane-bounded organelle	GO:0005524|ATP binding; GO:0046872|metal ion binding; GO:0050262|ribosylnicotinamide kinase activity; GO:0061769|ribosylnicotinate kinase activity	ko:K10524|NRK1_2	ko00760|Nicotinate and nicotinamide metabolism; ko01100|Metabolic pathways	1888	XP_015155322.1	XP_015155322.1 nicotinamide riboside kinase 2 [Gallus gallus]	sp|Q9NPI5|NRK2_HUMAN	sp|Q9NPI5|NRK2_HUMAN Nicotinamide riboside kinase 2 OS=Homo sapiens GN=NMRK2 PE=1 SV=1	59729.ENSTGUP00000001037	Nicotinamide riboside kinase 2 (NmR-K 2)(NRK 2)(EC 2.7.1.22)(Ribosylnicotinamide kinase 2)(R [...] 	COG0572	KOG3308	_	PF13238.3|AAA_18|AAA domain|ENSGALT00000085217|m.9779:82-225
ENSGALG00000025764	43.51872241	21.75157952	1.000184402	2.14E-52	8.40E-51	up	yes	43.78257965	43.72542277	43.04816482	21.6062855	21.41521496	22.23323809	27	7499025	7504478	+	FKBP10	protein_coding	GO:0000412|histone peptidyl-prolyl isomerization; GO:0061077|chaperone-mediated protein folding	GO:0005730|nucleolus; GO:0005737|cytoplasm; GO:0005788|endoplasmic reticulum lumen	GO:0003755|peptidyl-prolyl cis-trans isomerase activity; GO:0005509|calcium ion binding; GO:0005528|FK506 binding	ko:K09575|FKBP9_10	--	2496	XP_003642878.1	XP_003642878.1 peptidyl-prolyl cis-trans isomerase FKBP10 [Gallus gallus]	sp|Q2HJ89|FKB10_BOVIN	sp|Q2HJ89|FKB10_BOVIN Peptidyl-prolyl cis-trans isomerase FKBP10 OS=Bos taurus GN=FKBP10 PE=2 SV=1	_	_	_	_	_	PF00254.25|FKBP_C|FKBP-type peptidyl-prolyl cis-trans isomerase|ENSGALT00000045048|m.9336:40-129;PF00254.25|FKBP_C|FKBP-type peptidyl-prolyl cis-trans isomerase|ENSGALT00000045048|m.9336:151-241;PF00254.25|FKBP_C|FKBP-type peptidyl-prolyl cis-trans isomerase|ENSGALT00000045048|m.9336:264-354;PF00254.25|FKBP_C|FKBP-type peptidyl-prolyl cis-trans isomerase|ENSGALT00000045048|m.9336:378-465;PF13202.3|EF-hand_5|EF hand|ENSGALT00000045048|m.9336:487-507;PF13202.3|EF-hand_5|EF hand|ENSGALT00000045048|m.9336:537-550
ENSGALG00000025817	0.147969701	0.581585286	-1.904938296	0.001520537	0.003111371	down	yes	0.231915005	0	0.211994098	0.671704949	0.632878604	0.440172304	25	2427409	2432025	+	NHLH1	protein_coding	GO:0007275|multicellular organism development; GO:0030154|cell differentiation; GO:0045944|positive regulation of transcription by RNA polymerase II	GO:0005634|nucleus	"GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding; GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0046983|protein dimerization activity"	"ko:K09075|NHLH,HEN,NSCL"	--	2272	XP_015153845.1	XP_015153845.1 helix-loop-helix protein 1 isoform X1 [Gallus gallus]	sp|Q02576|HEN1_MOUSE	sp|Q02576|HEN1_MOUSE Helix-loop-helix protein 1 OS=Mus musculus GN=Nhlh1 PE=2 SV=1	9031.ENSGALP00000039947	nescient helix loop helix 1 	_	KOG4029	_	PF00010.23|HLH|Helix-loop-helix DNA-binding domain|ENSGALT00000044008|m.6873:74-124
ENSGALG00000025898	8.901155689	33.22919636	-1.89920105	1.14E-115	2.22E-113	down	yes	8.702044743	9.311032359	8.690389964	33.53132133	31.62509302	34.53117474	10	19113380	19141564	+	SMAD6	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0007179|transforming growth factor beta receptor signaling pathway; GO:0010693|negative regulation of alkaline phosphatase activity; GO:0031589|cell-substrate adhesion; GO:0032331|negative regulation of chondrocyte differentiation; GO:0050767|regulation of neurogenesis; GO:1902832|negative regulation of cell proliferation in dorsal spinal cord; GO:1902844|positive regulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway"	GO:0005634|nucleus; GO:0005667|transcription factor complex; GO:0005768|endosome	GO:0003682|chromatin binding; GO:0003700|DNA-binding transcription factor activity; GO:0044212|transcription regulatory region DNA binding; GO:0046872|metal ion binding	ko:K04677|SMAD6	ko04350|TGF-beta signaling pathway	2531	NP_989579.2	NP_989579.2 mothers against decapentaplegic homolog 6 [Gallus gallus]	sp|Q9W734|SMAD6_CHICK	sp|Q9W734|SMAD6_CHICK Mothers against decapentaplegic homolog 6 OS=Gallus gallus GN=SMAD6 PE=2 SV=1	_	_	_	_	_	PF03166.11|MH2|MH2 domain|ENSGALT00000071414|m.5822:264-427;PF03165.13|MH1|MH1 domain|ENSGALT00000071414|m.5822:107-204
ENSGALG00000025915	17.02851201	60.90821748	-1.838074379	2.85E-123	7.18E-121	down	yes	16.50723343	19.08661691	15.49168568	61.65080869	61.45977428	59.61406947	Z	59536399	59549088	+	ARRDC3	protein_coding	GO:0001659|temperature homeostasis; GO:0009892|negative regulation of metabolic process; GO:0031651|negative regulation of heat generation; GO:0043588|skin development; GO:0051443|positive regulation of ubiquitin-protein transferase activity; GO:0060613|fat pad development; GO:0071879|positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway; GO:0090327|negative regulation of locomotion involved in locomotory behavior	GO:0005764|lysosome; GO:0005768|endosome; GO:0005769|early endosome; GO:0005886|plasma membrane	GO:0031699|beta-3 adrenergic receptor binding	--	--	3192	XP_424699.2	XP_424699.2 arrestin domain-containing protein 3 isoform X1 [Gallus gallus]	sp|Q96B67|ARRD3_HUMAN	sp|Q96B67|ARRD3_HUMAN Arrestin domain-containing protein 3 OS=Homo sapiens GN=ARRDC3 PE=1 SV=1	9031.ENSGALP00000023577	arrestin domain containing 3	_	KOG3780	_	"PF00339.26|Arrestin_N|Arrestin (or S-antigen), N-terminal domain|ENSGALT00000094498|m.11728:18-165;PF02752.19|Arrestin_C|Arrestin (or S-antigen), C-terminal domain|ENSGALT00000094498|m.11728:188-313"
ENSGALG00000025938	0.279638608	0.600983468	-1.076879422	0.014467193	0.024770737	down	yes	0.301622263	0.272184252	0.265109308	0.645818877	0.44045724	0.716674286	11	17751603	17760523	-	KIAA0513	protein_coding	--	--	--	--	--	2161	XP_001235240.2	XP_001235240.2 uncharacterized protein KIAA0513 homolog isoform X1 [Gallus gallus]	sp|Q8R0A7|K0513_MOUSE	sp|Q8R0A7|K0513_MOUSE Uncharacterized protein KIAA0513 OS=Mus musculus GN=Kiaa0513 PE=1 SV=1	_	_	_	_	_	_
ENSGALG00000026055	0.210243771	0.586985637	-1.438595004	0.000536516	0.001175044	down	yes	0.145824047	0.225716449	0.259190816	0.432717004	0.743339313	0.584900593	28	2849820	2864572	+	PALM	protein_coding	GO:0007010|cytoskeleton organization; GO:0007194|negative regulation of adenylate cyclase activity; GO:0008104|protein localization; GO:0008360|regulation of cell shape; GO:0051491|positive regulation of filopodium assembly; GO:0060074|synapse maturation; GO:0060999|positive regulation of dendritic spine development; GO:0071257|cellular response to electrical stimulus; GO:0072659|protein localization to plasma membrane	GO:0005622|intracellular; GO:0005737|cytoplasm; GO:0005886|plasma membrane; GO:0014069|postsynaptic density; GO:0016323|basolateral plasma membrane; GO:0016327|apicolateral plasma membrane; GO:0030175|filopodium; GO:0030424|axon; GO:0031527|filopodium membrane; GO:0043197|dendritic spine; GO:0044306|neuron projection terminus; GO:0044309|neuron spine; GO:0097060|synaptic membrane	GO:0031750|D3 dopamine receptor binding	ko:K16519|AKAP2	--	3122	XP_021234133.1	XP_021234133.1 paralemmin-1 isoform X1 [Numida meleagris]	sp|Q9YGL6|PALM_CHICK	sp|Q9YGL6|PALM_CHICK Paralemmin-1 OS=Gallus gallus GN=PALM PE=1 SV=1	9031.ENSGALP00000002861	Paralemmin ; May be involved in control of cell shape	_	_	NOG46471	PF03285.12|Paralemmin|Paralemmin|ENSGALT00000087515|m.10021:134-450
ENSGALG00000026098	1.880301922	89.32259058	-5.562498012	1.01E-23	1.18E-22	down	yes	3.396685841	1.338618492	0.905601434	95.68055544	96.50483339	75.7823829	4	50937659	50940883	+	IL8	protein_coding	GO:0001525|angiogenesis; GO:0002232|leukocyte chemotaxis involved in inflammatory response; GO:0002269|leukocyte activation involved in inflammatory response; GO:0002548|monocyte chemotaxis; GO:0006955|immune response; GO:0007186|G protein-coupled receptor signaling pathway; GO:0010628|positive regulation of gene expression; GO:0030097|hemopoiesis; GO:0030593|neutrophil chemotaxis; GO:0030595|leukocyte chemotaxis; GO:0032496|response to lipopolysaccharide; GO:0036446|myofibroblast differentiation; GO:0042060|wound healing; GO:0042119|neutrophil activation; GO:0048147|negative regulation of fibroblast proliferation; GO:0048246|macrophage chemotaxis; GO:0048247|lymphocyte chemotaxis; GO:0050729|positive regulation of inflammatory response; GO:0070098|chemokine-mediated signaling pathway; GO:0090023|positive regulation of neutrophil chemotaxis	GO:0005615|extracellular space	GO:0005125|cytokine activity; GO:0005153|interleukin-8 receptor binding; GO:0008009|chemokine activity; GO:0008083|growth factor activity; GO:0045236|CXCR chemokine receptor binding	"ko:K10030|IL8,CXCL8"	ko04060|Cytokine-cytokine receptor interaction; ko04062|Chemokine signaling pathway; ko04064|NF-kappa B signaling pathway; ko04072|Phospholipase D signaling pathway; ko04620|Toll-like receptor signaling pathway; ko04621|NOD-like receptor signaling pathway; ko04622|RIG-I-like receptor signaling pathway; ko04657|IL-17 signaling pathway; ko04932|Non-alcoholic fatty liver disease (NAFLD); ko04933|AGE-RAGE signaling pathway in diabetic complications; ko05120|Epithelial cell signaling in Helicobacter pylori infection; ko05131|Shigellosis; ko05132|Salmonella infection; ko05133|Pertussis; ko05134|Legionellosis; ko05142|Chagas disease (American trypanosomiasis); ko05144|Malaria; ko05146|Amoebiasis; ko05160|Hepatitis C; ko05161|Hepatitis B; ko05164|Influenza A; ko05200|Pathways in cancer; ko05202|Transcriptional misregulation in cancer; ko05219|Bladder cancer; ko05323|Rheumatoid arthritis	1241	XP_021252456.1	XP_021252456.1 interleukin-8 [Numida meleagris]	sp|P08317|IL8_CHICK	sp|P08317|IL8_CHICK Interleukin-8 OS=Gallus gallus GN=CXCL8 PE=2 SV=1	9031.ENSGALP00000019051	Interleukin-8 Precursor (IL-8)(C-X-C motif chemokine 8)(Embryo fibroblast protein 1)(EMF-1)( [...] 	_	_	NOG73311	"PF00048.17|IL8|Small cytokines (intecrine/chemokine), interleukin-8 like|ENSGALT00000042745|m.708:32-91"
ENSGALG00000026161	1.350747768	0.618693601	1.113970686	0.004809067	0.009035602	up	yes	1.368186492	2.029640247	0.654416564	0.610388009	0.641784898	0.603907896	28	991209	993646	+	ENSGALG00000026161	protein_coding	GO:0051260|protein homooligomerization; GO:0071805|potassium ion transmembrane transport	GO:0008076|voltage-gated potassium channel complex; GO:0016021|integral component of membrane	GO:0005249|voltage-gated potassium channel activity	--	--	1656	XP_021234240.1	XP_021234240.1 potassium voltage-gated channel subfamily V member 2-like [Numida meleagris]	sp|Q8CFS6|KCNV2_MOUSE	sp|Q8CFS6|KCNV2_MOUSE Potassium voltage-gated channel subfamily V member 2 OS=Mus musculus GN=Kcnv2 PE=2 SV=1	_	_	_	_	_	PF00520.28|Ion_trans|Ion transport protein|ENSGALT00000068120|m.9593:230-465;PF02214.19|BTB_2|BTB/POZ domain|ENSGALT00000068120|m.9593:69-168;PF07885.13|Ion_trans_2|Ion channel|ENSGALT00000068120|m.9593:383-460
ENSGALG00000026163	0.360904693	1.178186349	-1.679640693	0.000936207	0.001980424	down	yes	0.131399225	0.417482111	0.533832742	1.268589895	1.108648813	1.157320339	1	167840281	167860165	+	TNFSF11	protein_coding	GO:0001503|ossification; GO:0002158|osteoclast proliferation; GO:0002548|monocyte chemotaxis; GO:0006955|immune response; GO:0007257|activation of JUN kinase activity; GO:0009887|animal organ morphogenesis; GO:0019221|cytokine-mediated signaling pathway; GO:0019722|calcium-mediated signaling; GO:0030316|osteoclast differentiation; GO:0033209|tumor necrosis factor-mediated signaling pathway; GO:0033598|mammary gland epithelial cell proliferation; GO:0034112|positive regulation of homotypic cell-cell adhesion; GO:0038001|paracrine signaling; GO:0043123|positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0043406|positive regulation of MAP kinase activity; GO:0045453|bone resorption; GO:0045672|positive regulation of osteoclast differentiation; GO:0045780|positive regulation of bone resorption; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0050870|positive regulation of T cell activation; GO:0051091|positive regulation of DNA-binding transcription factor activity; GO:0051092|positive regulation of NF-kappaB transcription factor activity; GO:0051260|protein homooligomerization; GO:0051466|positive regulation of corticotropin-releasing hormone secretion; GO:0051897|positive regulation of protein kinase B signaling; GO:0055074|calcium ion homeostasis; GO:0060749|mammary gland alveolus development; GO:0070371|ERK1 and ERK2 cascade; GO:0071812|positive regulation of fever generation by positive regulation of prostaglandin secretion; GO:0071847|TNFSF11-mediated signaling pathway; GO:0071848|positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling; GO:1902533|positive regulation of intracellular signal transduction; GO:1990830|cellular response to leukemia inhibitory factor; GO:2001206|positive regulation of osteoclast development	GO:0005576|extracellular region; GO:0005615|extracellular space; GO:0005737|cytoplasm; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane	GO:0005125|cytokine activity; GO:0005164|tumor necrosis factor receptor binding; GO:0032813|tumor necrosis factor receptor superfamily binding	"ko:K05473|TNFSF11,RANKL,CD254"	ko04060|Cytokine-cytokine receptor interaction; ko04064|NF-kappa B signaling pathway; ko04380|Osteoclast differentiation; ko04917|Prolactin signaling pathway; ko05224|Breast cancer; ko05323|Rheumatoid arthritis	1203	NP_001076830.1	NP_001076830.1 tumor necrosis factor ligand superfamily member 11 [Gallus gallus]	sp|O14788|TNF11_HUMAN	sp|O14788|TNF11_HUMAN Tumor necrosis factor ligand superfamily member 11 OS=Homo sapiens GN=TNFSF11 PE=1 SV=1	9031.ENSGALP00000027360	Tumor necrosis factor ligand superfamily member 11 	_	_	NOG40842	PF00229.15|TNF|TNF(Tumour Necrosis Factor) family|ENSGALT00000045029|m.4206:269-396
ENSGALG00000026167	0.287514405	2.198252312	-2.891873593	4.37E-34	8.37E-33	down	yes	0.412520164	0.220714158	0.229308893	1.94170578	2.279693576	2.37335758	18	1984539	2033615	-	PIK3R5	protein_coding	GO:0007186|G protein-coupled receptor signaling pathway; GO:0014065|phosphatidylinositol 3-kinase signaling; GO:0043406|positive regulation of MAP kinase activity	"GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005886|plasma membrane; GO:0005942|phosphatidylinositol 3-kinase complex; GO:0005944|phosphatidylinositol 3-kinase complex, class IB"	GO:0046935|1-phosphatidylinositol-3-kinase regulator activity	ko:K21290|PIK3R5_6	ko04022|cGMP-PKG signaling pathway; ko04072|Phospholipase D signaling pathway; ko04151|PI3K-Akt signaling pathway; ko04261|Adrenergic signaling in cardiomyocytes; ko04371|Apelin signaling pathway; ko04611|Platelet activation; ko04725|Cholinergic synapse; ko04921|Oxytocin signaling pathway; ko05145|Toxoplasmosis	4726	NP_001025868.1	NP_001025868.1 phosphoinositide 3-kinase regulatory subunit 5 [Gallus gallus]	sp|Q5ZIB8|PIRK5_CHICK	sp|Q5ZIB8|PIRK5_CHICK Phosphoinositide 3-kinase regulatory subunit 5 OS=Gallus gallus GN=PIK3R5 PE=2 SV=1	_	_	_	_	_	PF10486.6|PI3K_1B_p101|Phosphoinositide 3-kinase gamma adapter protein p101 subunit|ENSGALT00000039333|m.12560:4-881
ENSGALG00000026214	0.232159925	0.83959906	-1.810822038	9.41E-05	0.000231828	down	yes	0.234704183	0.193595975	0.268179617	0.761445647	0.916643385	0.840708149	1	61004967	61014569	+	LRTM2	protein_coding	GO:0006469|negative regulation of protein kinase activity; GO:0019221|cytokine-mediated signaling pathway; GO:0046426|negative regulation of receptor signaling pathway via JAK-STAT; GO:0051965|positive regulation of synapse assembly	GO:0005737|cytoplasm; GO:0016021|integral component of membrane	GO:0004860|protein kinase inhibitor activity	--	--	1783	XP_004937998.1	XP_004937998.1 leucine-rich repeat and transmembrane domain-containing protein 2 isoform X1 [Gallus gallus]	sp|Q8N967|LRTM2_HUMAN	sp|Q8N967|LRTM2_HUMAN Leucine-rich repeat and transmembrane domain-containing protein 2 OS=Homo sapiens GN=LRTM2 PE=2 SV=1	9031.ENSGALP00000021214	annotation not avaliable	_	KOG0619	_	PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000105988|m.1815:93-152;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000105988|m.1815:142-198;PF01462.15|LRRNT|Leucine rich repeat N-terminal domain|ENSGALT00000105988|m.1815:38-67;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000105988|m.1815:75-185
ENSGALG00000026241	1.020121444	0.350012451	1.516695725	4.84E-06	1.42E-05	up	yes	1.16685176	0.876152066	1.017360507	0.555246547	0.227962769	0.266828035	28	2984284	2988778	+	GRIN3B	protein_coding	GO:0035235|ionotropic glutamate receptor signaling pathway; GO:0051205|protein insertion into membrane; GO:0051924|regulation of calcium ion transport; GO:0070588|calcium ion transmembrane transport	GO:0017146|NMDA selective glutamate receptor complex; GO:0030054|cell junction; GO:0043025|neuronal cell body; GO:0045211|postsynaptic membrane	GO:0004970|ionotropic glutamate receptor activity; GO:0005234|extracellularly glutamate-gated ion channel activity; GO:0005261|cation channel activity; GO:0016594|glycine binding; GO:0030594|neurotransmitter receptor activity; GO:0042165|neurotransmitter binding	ko:K05214|GRIN3B	ko04024|cAMP signaling pathway; ko04080|Neuroactive ligand-receptor interaction; ko04724|Glutamatergic synapse; ko05030|Cocaine addiction; ko05031|Amphetamine addiction; ko05033|Nicotine addiction; ko05034|Alcoholism	3748	XP_015155474.2	"XP_015155474.2 glutamate receptor ionotropic, NMDA 3B isoform X1 [Gallus gallus]"	sp|Q8VHN2|NMD3B_RAT	"sp|Q8VHN2|NMD3B_RAT Glutamate receptor ionotropic, NMDA 3B OS=Rattus norvegicus GN=Grin3b PE=1 SV=2"	_	_	_	_	_	"PF00060.23|Lig_chan|Ligand-gated ion channel|ENSGALT00000044002|m.10070:833-1100;PF10613.6|Lig_chan-Glu_bd|Ligated ion channel L-glutamate- and glycine-binding site|ENSGALT00000044002|m.10070:732-818;PF00497.17|SBP_bac_3|Bacterial extracellular solute-binding proteins, family 3|ENSGALT00000044002|m.10070:735-1066"
ENSGALG00000026258	0.290090277	1.082693542	-1.864420356	5.35E-12	2.81E-11	down	yes	0.269290064	0.370206953	0.230773814	1.000268074	1.082782898	1.165029653	11	14531508	14691257	-	MAF	protein_coding	"GO:0006351|transcription, DNA-templated"	GO:0042025|host cell nucleus	GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity	"ko:K09035|CMAF,MAF"	ko04658|Th1 and Th2 cell differentiation; ko05202|Transcriptional misregulation in cancer; ko05321|Inflammatory bowel disease (IBD)	2898	NP_001038136.1	NP_001038136.1 transcription factor Maf [Gallus gallus]	sp|P23091|MAF_AVIS4	sp|P23091|MAF_AVIS4 Transforming protein Maf OS=Avian musculoaponeurotic fibrosarcoma virus AS42 GN=V-MAF PE=3 SV=1	13616.ENSMODP00000028169	v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)	_	KOG4196	_	PF03131.14|bZIP_Maf|bZIP Maf transcription factor|ENSGALT00000043755|m.6733:247-337;PF08383.8|Maf_N|Maf N-terminal region|ENSGALT00000043755|m.6733:87-119
ENSGALG00000026294	0.726496121	0.105446375	2.673455049	6.93E-06	1.99E-05	up	yes	0.713299028	0.568468986	0.897720349	0.034996453	0.073593172	0.207749502	9	12617353	12619381	-	ENSGALG00000026294	protein_coding	GO:0006506|GPI anchor biosynthetic process	GO:0005783|endoplasmic reticulum; GO:0005789|endoplasmic reticulum membrane; GO:0016021|integral component of membrane	"GO:0000026|alpha-1,2-mannosyltransferase activity; GO:0000030|mannosyltransferase activity"	"ko:K08098|PIGZ,SMP3"	ko00563|Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	1699	XP_426699.2	XP_426699.2 GPI mannosyltransferase 4 isoform X2 [Gallus gallus]	sp|Q8BTP0|PIGZ_MOUSE	sp|Q8BTP0|PIGZ_MOUSE GPI mannosyltransferase 4 OS=Mus musculus GN=Pigz PE=2 SV=2	_	_	_	_	_	PF03901.14|Glyco_transf_22|Alg9-like mannosyltransferase family|ENSGALT00000044130|m.8800:12-459
ENSGALG00000026328	31.3976386	15.066435	1.05882015	2.36E-28	3.42E-27	up	yes	31.26620479	31.00319103	31.92351997	14.93116304	15.81092408	14.45721788	27	7055145	7056891	-	MIEN1	protein_coding	GO:0006915|apoptotic process; GO:0030335|positive regulation of cell migration; GO:0043066|negative regulation of apoptotic process; GO:0051491|positive regulation of filopodium assembly	GO:0005829|cytosol; GO:0031235|intrinsic component of the cytoplasmic side of the plasma membrane; GO:0070062|extracellular exosome	--	ko:K07401|K07401	--	1119	XP_015155030.1	XP_015155030.1 migration and invasion enhancer 1 [Gallus gallus]	sp|Q9CQ86|MIEN1_MOUSE	sp|Q9CQ86|MIEN1_MOUSE Migration and invasion enhancer 1 OS=Mus musculus GN=Mien1 PE=1 SV=1	10116.ENSRNOP00000009485	"similar to RIKEN cDNA 1810046J19 (RGD1306682), mRNA"	_	_	NOG85235	PF10262.6|Rdx|Rdx family|ENSGALT00000045413|m.9216:39-108
ENSGALG00000026384	1.630473105	3.327342234	-1.024587696	1.59E-08	6.14E-08	down	yes	1.535623726	1.688880975	1.666914614	3.321326974	2.953159489	3.707540239	28	3324485	3329567	+	PCSK4	protein_coding	GO:0007339|binding of sperm to zona pellucida; GO:0007340|acrosome reaction; GO:0009566|fertilization; GO:0016485|protein processing; GO:0022414|reproductive process; GO:0048240|sperm capacitation	GO:0001669|acrosomal vesicle; GO:0002080|acrosomal membrane; GO:0016021|integral component of membrane	GO:0004252|serine-type endopeptidase activity	ko:K08671|PCSK4	--	2745	XP_015155436.1	XP_015155436.1 proprotein convertase subtilisin/kexin type 4 [Gallus gallus]	sp|Q6UW60|PCSK4_HUMAN	sp|Q6UW60|PCSK4_HUMAN Proprotein convertase subtilisin/kexin type 4 OS=Homo sapiens GN=PCSK4 PE=1 SV=2	_	_	_	_	_	PF00082.19|Peptidase_S8|Subtilase family|ENSGALT00000093065|m.10152:173-456;PF01483.17|P_proprotein|Proprotein convertase P-domain|ENSGALT00000093065|m.10152:513-598
ENSGALG00000026460	1.414741539	4.114914152	-1.53366387	9.28E-26	1.20E-24	down	yes	1.23285356	1.729256054	1.282115002	4.117165924	4.205985776	4.021590758	7	26259270	26296906	-	ENSGALG00000026460	protein_coding	--	--	--	--	--	4433	XP_004942977.1	XP_004942977.1 uncharacterized protein ARHGEF1 isoform X1 [Gallus gallus]	_	_	_	_	_	_	_	PF00621.17|RhoGEF|RhoGEF domain|ENSGALT00000106024|m.6535:792-975
ENSGALG00000026492	17.26650207	4.263057206	2.015470612	0.003777887	0.007227392	up	yes	34.96899335	7.972570951	8.857941908	3.606441693	4.70953354	4.473196385	19	6786474	6788567	-	EMC6	protein_coding	GO:0000045|autophagosome assembly; GO:0034975|protein folding in endoplasmic reticulum	GO:0016021|integral component of membrane; GO:0030176|integral component of endoplasmic reticulum membrane; GO:0072546|ER membrane protein complex; GO:0097631|integral component of omegasome membrane	--	--	--	1885	RLV97139.1	RLV97139.1 hypothetical protein DV515_00012091 [Erythrura gouldiae]	sp|Q9BV81|EMC6_HUMAN	sp|Q9BV81|EMC6_HUMAN ER membrane protein complex subunit 6 OS=Homo sapiens GN=EMC6 PE=1 SV=1	9031.ENSGALP00000038679	transmembrane protein 93	_	KOG4455	_	PF07019.9|Rab5ip|Rab5-interacting protein (Rab5ip)|ENSGALT00000084902|m.14050:26-104
ENSGALG00000026536	0.601289095	2.087433326	-1.778698214	1.40E-06	4.40E-06	down	yes	0.576585992	0.585350792	0.641930502	1.835153491	2.017256156	2.409890332	26	4604661	4612635	+	IP6K3	protein_coding	GO:0006468|protein phosphorylation; GO:0032958|inositol phosphate biosynthetic process; GO:0043647|inositol phosphate metabolic process; GO:0046488|phosphatidylinositol metabolic process	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005829|cytosol	"GO:0000827|inositol-1,3,4,5,6-pentakisphosphate kinase activity; GO:0000828|inositol hexakisphosphate kinase activity; GO:0000829|inositol heptakisphosphate kinase activity; GO:0000831|inositol hexakisphosphate 6-kinase activity; GO:0000832|inositol hexakisphosphate 5-kinase activity; GO:0005524|ATP binding; GO:0008440|inositol-1,4,5-trisphosphate 3-kinase activity; GO:0052723|inositol hexakisphosphate 1-kinase activity; GO:0052724|inositol hexakisphosphate 3-kinase activity; GO:0052836|inositol 5-diphosphate pentakisphosphate 5-kinase activity; GO:0052839|inositol diphosphate tetrakisphosphate kinase activity"	"ko:K07756|IP6K,IHPK"	ko04070|Phosphatidylinositol signaling system; ko04138|Autophagy - yeast	1188	XP_418033.2	XP_418033.2 inositol hexakisphosphate kinase 3 [Gallus gallus]	sp|Q96PC2|IP6K3_HUMAN	sp|Q96PC2|IP6K3_HUMAN Inositol hexakisphosphate kinase 3 OS=Homo sapiens GN=IP6K3 PE=1 SV=2	_	_	_	_	_	PF03770.13|IPK|Inositol polyphosphate kinase|ENSGALT00000045156|m.8235:184-389
ENSGALG00000026590	1.897517659	0.586480596	1.677149302	3.02E-11	1.49E-10	up	yes	1.608728732	2.205858022	1.877966223	0.518674627	0.603194576	0.637572585	10	6022200	6048656	-	KLF13	protein_coding	GO:0006357|regulation of transcription by RNA polymerase II; GO:0006366|transcription by RNA polymerase II; GO:0008285|negative regulation of cell population proliferation; GO:0045647|negative regulation of erythrocyte differentiation; GO:0045944|positive regulation of transcription by RNA polymerase II	GO:0005634|nucleus	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003677|DNA binding; GO:0046872|metal ion binding"	"ko:K09208|KLF9S,BTEB"	--	2522	XP_425065.1	XP_425065.1 Krueppel-like factor 13 [Gallus gallus]	sp|Q9JJZ6|KLF13_MOUSE	sp|Q9JJZ6|KLF13_MOUSE Krueppel-like factor 13 OS=Mus musculus GN=Klf13 PE=1 SV=2	_	_	_	_	_	PF13894.3|zf-C2H2_4|C2H2-type zinc finger|ENSGALT00000045929|m.5378:215-237
ENSGALG00000026627	0.883223207	0.279335787	1.626275956	0.000281136	0.000644096	up	yes	1.074751147	0.497689563	1.077228912	0.234048561	0.246087455	0.357871346	4	58088312	58100247	-	LRIT3	protein_coding	GO:0007601|visual perception; GO:0040036|regulation of fibroblast growth factor receptor signaling pathway; GO:0050896|response to stimulus	GO:0005789|endoplasmic reticulum membrane; GO:0016021|integral component of membrane; GO:0030425|dendrite; GO:0043204|perikaryon	--	--	--	1863	XP_003205787.2	"XP_003205787.2 PREDICTED: leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 [Meleagris gallopavo]"	sp|Q3SXY7|LRIT3_HUMAN	"sp|Q3SXY7|LRIT3_HUMAN Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 OS=Homo sapiens GN=LRIT3 PE=1 SV=3"	9031.ENSGALP00000019835	"leucine-rich repeat, immunoglobulin-like and transmembrane domains 3"	_	KOG0619;KOG3510	_	PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000043553|m.883:61-117;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000043553|m.883:90-140;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000043553|m.883:129-171;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000043553|m.883:258-337;PF12799.4|LRR_4|Leucine Rich repeats (2 copies)|ENSGALT00000043553|m.883:129-169;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000043553|m.883:261-350;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000043553|m.883:265-350;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000043553|m.883:425-491;PF00560.30|LRR_1|Leucine Rich Repeat|ENSGALT00000043553|m.883:154-171;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000043553|m.883:266-346
ENSGALG00000026639	3.487654276	1.49521118	1.216421784	1.76E-07	6.14E-07	up	yes	2.600633153	4.352447415	3.509882259	1.786321081	1.352754888	1.34655757	1	187190153	187219427	+	SMCO4	protein_coding	--	--	--	--	--	1549	XP_015707821.1	XP_015707821.1 PREDICTED: single-pass membrane and coiled-coil domain-containing protein 4 isoform X1 [Coturnix japonica]	_	_	_	_	_	_	_	_
ENSGALG00000026663	1.123913682	4.811206702	-2.088083464	1.30E-36	2.81E-35	down	yes	1.32236324	1.097411662	0.951966144	4.274399427	5.091966899	5.06725378	11	771897	778309	+	CX3CL1	protein_coding	GO:0002548|monocyte chemotaxis; GO:0006954|inflammatory response; GO:0007186|G protein-coupled receptor signaling pathway; GO:0030593|neutrophil chemotaxis; GO:0043547|positive regulation of GTPase activity; GO:0048247|lymphocyte chemotaxis; GO:0070098|chemokine-mediated signaling pathway; GO:0070374|positive regulation of ERK1 and ERK2 cascade; GO:0071346|cellular response to interferon-gamma; GO:0071347|cellular response to interleukin-1; GO:0071356|cellular response to tumor necrosis factor	GO:0005615|extracellular space	GO:0008009|chemokine activity; GO:0048020|CCR chemokine receptor binding	"ko:K05508|CX3CL1,NTT"	ko04060|Cytokine-cytokine receptor interaction; ko04062|Chemokine signaling pathway; ko04668|TNF signaling pathway	3626	NP_001070700.1	NP_001070700.1 fractalkine precursor [Gallus gallus]	sp|Q68Y88|CCL13_CANLF	sp|Q68Y88|CCL13_CANLF C-C motif chemokine 13 OS=Canis lupus familiaris GN=CCL13 PE=3 SV=1	_	_	_	_	_	"PF00048.17|IL8|Small cytokines (intecrine/chemokine), interleukin-8 like|ENSGALT00000043370|m.6194:90-143"
ENSGALG00000026850	6.291954909	2.05326535	1.610870058	1.63E-24	1.98E-23	up	yes	6.540157347	6.108233906	6.227473474	1.932910836	2.517324175	1.709561038	28	4961810	4965486	+	TICAM1	protein_coding	GO:0006915|apoptotic process; GO:0006954|inflammatory response; GO:0045087|innate immune response; GO:0051607|defense response to virus	GO:0005776|autophagosome; GO:0031410|cytoplasmic vesicle	--	ko:K05842|TRIF	ko04064|NF-kappa B signaling pathway; ko04620|Toll-like receptor signaling pathway; ko04621|NOD-like receptor signaling pathway; ko05133|Pertussis; ko05142|Chagas disease (American trypanosomiasis); ko05160|Hepatitis C; ko05161|Hepatitis B; ko05164|Influenza A; ko05168|Herpes simplex infection	2707	XP_015155511.1	XP_015155511.1 TIR domain-containing adapter molecule 1 isoform X1 [Gallus gallus]	sp|Q4JF29|TCAM1_BOVIN	sp|Q4JF29|TCAM1_BOVIN TIR domain-containing adapter molecule 1 OS=Bos taurus GN=TICAM1 PE=2 SV=2	_	_	_	_	_	PF12721.4|RHIM|RIP homotypic interaction motif|ENSGALT00000046189|m.10492:677-716
ENSGALG00000026906	37.27521214	78.22212653	-1.069157631	7.19E-59	3.42E-57	down	yes	37.54240099	37.15600235	37.12723307	83.54860118	73.97126125	77.14651715	20	13716784	13750656	+	TMEM189	protein_coding	--	GO:0005737|cytoplasm; GO:0005783|endoplasmic reticulum; GO:0005789|endoplasmic reticulum membrane; GO:0016021|integral component of membrane	GO:0031625|ubiquitin protein ligase binding; GO:0061630|ubiquitin protein ligase activity	ko:K20656|TMEM189	--	2001	NP_001192029.1	NP_001192029.1 transmembrane protein 189 [Gallus gallus]	sp|A5PLL7|TM189_HUMAN	sp|A5PLL7|TM189_HUMAN Transmembrane protein 189 OS=Homo sapiens GN=TMEM189 PE=1 SV=3	28377.ENSACAP00000015319	transmembrane protein 189	_	KOG3011	_	"PF10520.6|TMEM189_B_dmain|B domain of TMEM189, localisation domain|ENSGALT00000038844|m.3668:135-311"
ENSGALG00000026928	1.833962339	7.303542125	-1.987761117	3.17E-31	5.35E-30	down	yes	1.995466015	1.739875845	1.766545157	7.901490968	7.476065681	6.533069727	Z	55788643	55792227	-	ENSGALG00000026928	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006351|transcription, DNA-templated; GO:0006357|regulation of transcription by RNA polymerase II; GO:0006366|transcription by RNA polymerase II; GO:0008285|negative regulation of cell population proliferation; GO:0009913|epidermal cell differentiation; GO:0010033|response to organic substance; GO:0010628|positive regulation of gene expression; GO:0010629|negative regulation of gene expression; GO:0014067|negative regulation of phosphatidylinositol 3-kinase signaling; GO:0014740|negative regulation of muscle hyperplasia; GO:0019827|stem cell population maintenance; GO:0030154|cell differentiation; GO:0030336|negative regulation of cell migration; GO:0031077|post-embryonic camera-type eye development; GO:0032088|negative regulation of NF-kappaB transcription factor activity; GO:0032270|positive regulation of cellular protein metabolic process; GO:0032526|response to retinoic acid; GO:0034115|negative regulation of heterotypic cell-cell adhesion; GO:0035166|post-embryonic hemopoiesis; GO:0042127|regulation of cell population proliferation; GO:0043154|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0043433|negative regulation of DNA-binding transcription factor activity; GO:0045415|negative regulation of interleukin-8 biosynthetic process; GO:0045429|positive regulation of nitric oxide biosynthetic process; GO:0045444|fat cell differentiation; GO:0045595|regulation of cell differentiation; GO:0045892|negative regulation of transcription, DNA-templated; GO:0045893|positive regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0046985|positive regulation of hemoglobin biosynthetic process; GO:0048662|negative regulation of smooth muscle cell proliferation; GO:0048679|regulation of axon regeneration; GO:0048730|epidermis morphogenesis; GO:0051247|positive regulation of protein metabolic process; GO:0051898|negative regulation of protein kinase B signaling; GO:0051973|positive regulation of telomerase activity; GO:0060070|canonical Wnt signaling pathway; GO:0060761|negative regulation of response to cytokine stimulus; GO:0070301|cellular response to hydrogen peroxide; GO:0070373|negative regulation of ERK1 and ERK2 cascade; GO:0071300|cellular response to retinoic acid; GO:0071363|cellular response to growth factor stimulus; GO:0071409|cellular response to cycloheximide; GO:0071499|cellular response to laminar fluid shear stress; GO:0090051|negative regulation of cell migration involved in sprouting angiogenesis; GO:1901653|cellular response to peptide; GO:1904798|positive regulation of core promoter binding; GO:1904998|negative regulation of leukocyte adhesion to arterial endothelial cell; GO:1990830|cellular response to leukemia inhibitory factor; GO:2000342|negative regulation of chemokine (C-X-C motif) ligand 2 production"	GO:0000790|nuclear chromatin; GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005719|nuclear euchromatin; GO:0005737|cytoplasm; GO:0044798|nuclear transcription factor complex	"GO:0000987|proximal promoter sequence-specific DNA binding; GO:0001010|RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity; GO:0001047|core promoter binding; GO:0001085|RNA polymerase II transcription factor binding; GO:0001221|transcription cofactor binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity; GO:0008013|beta-catenin binding; GO:0008134|transcription factor binding; GO:0035014|phosphatidylinositol 3-kinase regulator activity; GO:0042826|histone deacetylase binding; GO:0043565|sequence-specific DNA binding; GO:0044212|transcription regulatory region DNA binding; GO:0046872|metal ion binding; GO:1990841|promoter-specific chromatin binding"	ko:K17846|KLF4	ko04550|Signaling pathways regulating pluripotency of stem cells	1954	XP_004949426.1	XP_004949426.1 Krueppel-like factor 4 [Gallus gallus]	sp|Q60793|KLF4_MOUSE	sp|Q60793|KLF4_MOUSE Krueppel-like factor 4 OS=Mus musculus GN=Klf4 PE=1 SV=3	59729.ENSTGUP00000006577	Krueppel-like factor 4 (Epithelial zinc finger protein EZF)(Gut-enriched krueppel-like facto [...] 	COG5048	KOG1721	_	"PF00096.23|zf-C2H2|Zinc finger, C2H2 type|ENSGALT00000042652|m.11635:337-359"
ENSGALG00000026945	10.79660532	27.53895749	-1.350084325	2.95E-18	2.48E-17	down	yes	12.64344159	8.870987898	10.87538648	30.12770011	22.29859024	30.19058213	11	18370500	18371801	-	CIDEC	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated; GO:0006915|apoptotic process; GO:0034389|lipid droplet organization; GO:0042981|regulation of apoptotic process; GO:0097194|execution phase of apoptosis"	GO:0005634|nucleus; GO:0005783|endoplasmic reticulum; GO:0005811|lipid droplet; GO:0005829|cytosol	--	--	--	871	POI19492.1	POI19492.1 hypothetical protein CIB84_016763 [Bambusicola thoracicus]	sp|Q96AQ7|CIDEC_HUMAN	sp|Q96AQ7|CIDEC_HUMAN Cell death activator CIDE-3 OS=Homo sapiens GN=CIDEC PE=1 SV=1	_	_	_	_	_	PF02017.12|CIDE-N|CIDE-N domain|ENSGALT00000045824|m.6846:45-118
ENSGALG00000026948	1.640352859	0.418208342	1.94638971	6.90E-13	3.91E-12	up	yes	1.985404909	1.527058476	1.40859519	0.424654653	0.438799627	0.391170746	22	4084885	4104541	+	ADD2	protein_coding	GO:0030036|actin cytoskeleton organization; GO:0030097|hemopoiesis; GO:0032092|positive regulation of protein binding; GO:0050900|leukocyte migration; GO:0050901|leukocyte tethering or rolling; GO:0051016|barbed-end actin filament capping; GO:0051017|actin filament bundle assembly; GO:0055085|transmembrane transport; GO:0065003|protein-containing complex assembly	GO:0005829|cytosol; GO:0008290|F-actin capping protein complex; GO:0014069|postsynaptic density; GO:0031410|cytoplasmic vesicle; GO:0044853|plasma membrane raft	GO:0003779|actin binding; GO:0005198|structural molecule activity; GO:0005516|calmodulin binding; GO:0019901|protein kinase binding; GO:0030507|spectrin binding; GO:0042803|protein homodimerization activity; GO:0046982|protein heterodimerization activity; GO:0051015|actin filament binding	ko:K18622|ADD	--	2707	XP_015152973.2	XP_015152973.2 beta-adducin [Gallus gallus]	sp|P35612|ADDB_HUMAN	sp|P35612|ADDB_HUMAN Beta-adducin OS=Homo sapiens GN=ADD2 PE=1 SV=3	_	_	_	_	_	PF00596.18|Aldolase_II|Class II Aldolase and Adducin N-terminal domain|ENSGALT00000064031|m.4988:202-380
ENSGALG00000026955	10.53108163	4.257857086	1.304439139	5.73E-10	2.53E-09	up	yes	11.82681062	10.35394366	9.412490616	4.216242091	4.188770483	4.368558684	28	3364129	3364725	+	DIRAS1	protein_coding	GO:0007165|signal transduction	GO:0005886|plasma membrane	GO:0003924|GTPase activity; GO:0005525|GTP binding	ko:K07840|DIRAS1	--	597	XP_003214054.1	XP_003214054.1 PREDICTED: GTP-binding protein Di-Ras1 [Meleagris gallopavo]	sp|O95057|DIRA1_HUMAN	sp|O95057|DIRA1_HUMAN GTP-binding protein Di-Ras1 OS=Homo sapiens GN=DIRAS1 PE=1 SV=1	_	_	_	_	_	"PF00071.19|Ras|Ras family|ENSGALT00000046091|m.10173:9-166;PF08477.10|Roc|Ras of Complex, Roc, domain of DAPkinase|ENSGALT00000046091|m.10173:9-125;PF00025.18|Arf|ADP-ribosylation factor family|ENSGALT00000046091|m.10173:4-164"
ENSGALG00000026983	0.393869335	0.906290965	-1.181917185	1.58E-06	4.93E-06	down	yes	0.425500047	0.401113291	0.354994668	0.804066098	1.013709034	0.901097763	9	16088106	16096383	-	CHRD	protein_coding	GO:0009798|axis specification; GO:0036342|post-anal tail morphogenesis; GO:0043009|chordate embryonic development; GO:0048793|pronephros development	GO:0005576|extracellular region	GO:0008201|heparin binding; GO:0045545|syndecan binding	ko:K04657|CHRD	ko04350|TGF-beta signaling pathway	5201	XP_015146860.1	XP_015146860.1 chordin isoform X3 [Gallus gallus]	sp|Q91713|CHRD_XENLA	sp|Q91713|CHRD_XENLA Chordin OS=Xenopus laevis GN=chrd PE=1 SV=1	_	_	_	_	_	PF07452.9|CHRD|CHRD domain|ENSGALT00000048856|m.9135:677-788;PF07452.9|CHRD|CHRD domain|ENSGALT00000048856|m.9135:805-919;PF00093.15|VWC|von Willebrand factor type C domain|ENSGALT00000048856|m.9135:307-380;PF00093.15|VWC|von Willebrand factor type C domain|ENSGALT00000048856|m.9135:960-1017;PF00093.15|VWC|von Willebrand factor type C domain|ENSGALT00000048856|m.9135:1045-1105;PF00093.15|VWC|von Willebrand factor type C domain|ENSGALT00000048856|m.9135:1127-1188
ENSGALG00000026995	1.316793043	0.484957563	1.422566612	0.001315161	0.002723875	up	yes	1.660750659	1.25456273	1.03506574	0.530038601	0.437880544	0.486953543	1	197093201	197097605	-	RHOG	protein_coding	GO:0007264|small GTPase mediated signal transduction; GO:0060326|cell chemotaxis; GO:0090630|activation of GTPase activity; GO:1903078|positive regulation of protein localization to plasma membrane	GO:0005622|intracellular; GO:0005886|plasma membrane	GO:0003924|GTPase activity; GO:0005525|GTP binding	ko:K07863|RHOG	ko05100|Bacterial invasion of epithelial cells; ko05131|Shigellosis; ko05132|Salmonella infection	1047	XP_003213913.2	XP_003213913.2 PREDICTED: rho-related GTP-binding protein RhoG [Meleagris gallopavo]	sp|P84097|RHOG_CRICR	sp|P84097|RHOG_CRICR Rho-related GTP-binding protein RhoG OS=Cricetus cricetus GN=RHOG PE=2 SV=1	_	_	_	_	_	"PF00071.19|Ras|Ras family|ENSGALT00000043497|m.4969:162-334;PF08477.10|Roc|Ras of Complex, Roc, domain of DAPkinase|ENSGALT00000043497|m.4969:162-275;PF00025.18|Arf|ADP-ribosylation factor family|ENSGALT00000043497|m.4969:158-327"
ENSGALG00000027050	8.021350617	3.23043549	1.30945491	3.99E-24	4.74E-23	up	yes	7.667400445	7.533791543	8.862859864	3.278124434	3.252808855	3.160373181	10	2022414	2025732	+	SENP8	protein_coding	GO:0016926|protein desumoylation	GO:0005634|nucleus	GO:0004175|endopeptidase activity; GO:0008234|cysteine-type peptidase activity	"ko:K08597|SENP8,NEDP1,DEN1"	--	2364	NP_001280140.1	NP_001280140.1 sentrin-specific protease 8 [Gallus gallus]	sp|Q5FVJ8|SENP8_RAT	sp|Q5FVJ8|SENP8_RAT Sentrin-specific protease 8 OS=Rattus norvegicus GN=Senp8 PE=2 SV=1	_	_	_	_	_	"PF02902.16|Peptidase_C48|Ulp1 protease family, C-terminal catalytic domain|ENSGALT00000043189|m.5139:73-203"
ENSGALG00000027053	0.921207912	0.199442272	2.152550663	0.000149208	0.000356723	up	yes	1.145458459	0.571098773	1.047066503	0.13787588	0.289935766	0.170515171	2	100257486	100276143	+	AKAIN1	protein_coding	GO:0008104|protein localization; GO:0010738|regulation of protein kinase A signaling	GO:0005829|cytosol	GO:0034237|protein kinase A regulatory subunit binding; GO:0051018|protein kinase A binding	--	--	1150	NP_001138665.1	NP_001138665.1 A-kinase anchor protein inhibitor 1 [Gallus gallus]	sp|P0CW23|AKAI1_HUMAN	sp|P0CW23|AKAI1_HUMAN A-kinase anchor protein inhibitor 1 OS=Homo sapiens GN=AKAIN1 PE=1 SV=1	_	_	_	_	_	_
ENSGALG00000027064	19.02147382	4.270542956	2.152521581	4.12E-34	7.93E-33	up	yes	19.9752367	18.16650053	18.92268422	5.442579151	3.342364005	4.026685711	1	48172185	48173007	+	HIST1H3H	protein_coding	GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006334|nucleosome assembly	GO:0000786|nucleosome; GO:0005634|nucleus	GO:0031492|nucleosomal DNA binding; GO:0046982|protein heterodimerization activity	--	--	823	RMC03306.1	RMC03306.1 hypothetical protein DUI87_20501 [Hirundo rustica rustica]	sp|P84227|H32_BOVIN	sp|P84227|H32_BOVIN Histone H3.2 OS=Bos taurus PE=1 SV=2	9031.ENSGALP00000019166	Histone H3.2 (Histone H3 class I)	COG2036	KOG1745	_	PF00125.21|Histone|Core histone H2A/H2B/H3/H4|ENSGALT00000042655|m.1214:13-144
ENSGALG00000027069	9.012415121	23.95103659	-1.409104752	1.62E-22	1.76E-21	down	yes	10.86210607	7.269056391	8.906082896	26.57973586	20.15178543	25.12158849	4	1786951	1794312	+	TSC22D3	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006355|regulation of transcription, DNA-templated; GO:0006970|response to osmotic stress; GO:0034220|ion transmembrane transport; GO:0048642|negative regulation of skeletal muscle tissue development; GO:0070236|negative regulation of activation-induced cell death of T cells"	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005829|cytosol	GO:0003700|DNA-binding transcription factor activity; GO:0043426|MRF binding	--	--	1212	XP_015133803.1	XP_015133803.1 TSC22 domain family protein 3 isoform X1 [Gallus gallus]	sp|Q99576|T22D3_HUMAN	sp|Q99576|T22D3_HUMAN TSC22 domain family protein 3 OS=Homo sapiens GN=TSC22D3 PE=1 SV=2	59729.ENSTGUP00000005082	TSC22 domain family protein 3 (Glucocorticoid-induced leucine zipper protein)(Delta sleep-in [...] 	_	KOG4797	_	PF01166.15|TSC22|TSC-22/dip/bun family|ENSGALT00000042857|m.16025:119-173
ENSGALG00000027122	20.38038141	43.68249544	-1.099496744	3.88E-64	2.17E-62	down	yes	19.45242578	20.96854413	20.72017432	44.99839869	42.98402063	43.065067	1	54211821	54244951	+	APPL2	protein_coding	GO:0007049|cell cycle; GO:0007165|signal transduction; GO:0008283|cell population proliferation	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0010008|endosome membrane; GO:0031901|early endosome membrane; GO:0070062|extracellular exosome	--	"ko:K20132|APPL2,DIP13B"	--	3313	XP_003640457.1	XP_003640457.1 DCC-interacting protein 13-beta [Gallus gallus]	sp|Q8NEU8|DP13B_HUMAN	sp|Q8NEU8|DP13B_HUMAN DCC-interacting protein 13-beta OS=Homo sapiens GN=APPL2 PE=1 SV=3	9031.ENSGALP00000020645	"adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2"	_	KOG0521;KOG3536	_	PF16746.2|BAR_3|BAR domain of APPL family|ENSGALT00000105962|m.1554:2-226;PF00169.26|PH|PH domain|ENSGALT00000105962|m.1554:259-353;PF00640.20|PID|Phosphotyrosine interaction domain (PTB/PID)|ENSGALT00000105962|m.1554:469-584;PF08416.10|PTB|Phosphotyrosine-binding domain|ENSGALT00000105962|m.1554:471-584
ENSGALG00000027126	38.22584307	14.9388404	1.354892108	2.51E-67	1.52E-65	up	yes	36.88376237	37.27795795	40.5158089	14.77654061	14.78378294	15.25619764	20	5086332	5093930	-	BLCAP	protein_coding	GO:0006915|apoptotic process; GO:0007049|cell cycle	GO:0016021|integral component of membrane	--	--	--	1784	XP_003642526.2	XP_003642526.2 bladder cancer-associated protein isoform X2 [Gallus gallus]	sp|Q4G2S9|BLCAP_DIDVI	sp|Q4G2S9|BLCAP_DIDVI Bladder cancer-associated protein OS=Didelphis virginiana GN=BLCAP PE=3 SV=1	9031.ENSGALP00000006150	annotation not avaliable	_	KOG4489	_	PF06726.9|BC10|Bladder cancer-related protein BC10|ENSGALT00000045586|m.2993:55-119
ENSGALG00000027138	0.189323716	2.868219863	-3.85199152	8.40E-07	2.71E-06	down	yes	0.379072583	0.092645449	0.096253116	2.899278465	3.448201889	2.257179236	25	2538236	2543668	+	ENSGALG00000027138	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006357|regulation of transcription by RNA polymerase II; GO:0030154|cell differentiation"	GO:0005634|nucleus	"GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0001227|DNA-binding transcription repressor activity, RNA polymerase II-specific; GO:0043565|sequence-specific DNA binding"	--	--	417	XP_015153943.1	XP_015153943.1 ETS translocation variant 3-like protein [Gallus gallus]	sp|Q6ZN32|ETV3L_HUMAN	sp|Q6ZN32|ETV3L_HUMAN ETS translocation variant 3-like protein OS=Homo sapiens GN=ETV3L PE=2 SV=1	_	_	_	_	_	PF00178.19|Ets|Ets-domain|ENSGALT00000044892|m.6901:25-104
ENSGALG00000027247	4.093383876	10.29041797	-1.327816848	2.31E-34	4.49E-33	down	yes	3.686605379	4.485364458	4.108181792	10.37913025	10.49278687	9.999336775	2	38541856	38546582	-	EOMES	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0001706|endoderm formation; GO:0001707|mesoderm formation; GO:0001714|endodermal cell fate specification; GO:0001829|trophectodermal cell differentiation; GO:0002250|adaptive immune response; GO:0002302|CD8-positive, alpha-beta T cell differentiation involved in immune response; GO:0006351|transcription, DNA-templated; GO:0007420|brain development; GO:0010002|cardioblast differentiation; GO:0019827|stem cell population maintenance; GO:0021772|olfactory bulb development; GO:0021796|cerebral cortex regionalization; GO:0021895|cerebral cortex neuron differentiation; GO:0032609|interferon-gamma production; GO:0035914|skeletal muscle cell differentiation; GO:0045597|positive regulation of cell differentiation; GO:0045664|regulation of neuron differentiation; GO:0045893|positive regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0060706|cell differentiation involved in embryonic placenta development; GO:0060809|mesodermal to mesenchymal transition involved in gastrulation"	GO:0005634|nucleus	GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding; GO:0001102|RNA polymerase II activating transcription factor binding; GO:0003677|DNA binding; GO:0003682|chromatin binding; GO:0003700|DNA-binding transcription factor activity; GO:0043565|sequence-specific DNA binding	"ko:K10173|EOMES,TBR2"	--	3273	NP_001308484.1	NP_001308484.1 eomesodermin homolog [Gallus gallus]	sp|O95936|EOMES_HUMAN	sp|O95936|EOMES_HUMAN Eomesodermin homolog OS=Homo sapiens GN=EOMES PE=1 SV=3	_	_	_	_	_	PF16176.2|T-box_assoc|T-box transcription factor-associated|ENSGALT00000042658|m.415:460-680;PF00907.19|T-box|T-box|ENSGALT00000042658|m.415:248-434
ENSGALG00000027330	0.933865818	0.435160881	1.084254959	2.19E-05	5.90E-05	up	yes	1.069557805	0.973490538	0.758549111	0.43468218	0.413281922	0.45751854	13	13797199	13806846	-	SYNPO	protein_coding	GO:0008542|visual learning; GO:0032233|positive regulation of actin filament bundle assembly; GO:0048169|regulation of long-term neuronal synaptic plasticity; GO:0051492|regulation of stress fiber assembly; GO:0098886|modification of dendritic spine; GO:1905355|spine apparatus assembly	GO:0005634|nucleus; GO:0005923|bicellular tight junction; GO:0014069|postsynaptic density; GO:0015629|actin cytoskeleton; GO:0030018|Z disc; GO:0043197|dendritic spine; GO:0043204|perikaryon; GO:0045211|postsynaptic membrane; GO:0097444|spine apparatus	GO:0003779|actin binding	ko:K21112|SYNPO	ko04530|Tight junction	4286	XP_025010782.1	XP_025010782.1 synaptopodin isoform X2 [Gallus gallus]	sp|Q8N3V7|SYNPO_HUMAN	sp|Q8N3V7|SYNPO_HUMAN Synaptopodin OS=Homo sapiens GN=SYNPO PE=1 SV=2	_	_	_	_	_	_
ENSGALG00000027345	0.440924693	0.168668026	1.335605037	0.003052235	0.005923571	up	yes	0.4125281	0.467447394	0.442798586	0.126958661	0.155737294	0.223308124	Z	66053892	66060597	+	SLC46A2	protein_coding	GO:0043029|T cell homeostasis; GO:0045580|regulation of T cell differentiation; GO:0048538|thymus development; GO:0070233|negative regulation of T cell apoptotic process	GO:0005886|plasma membrane; GO:0009986|cell surface; GO:0016021|integral component of membrane	GO:0015293|symporter activity	ko:K14614|SLC46A2	--	2810	XP_429188.3	XP_429188.3 thymic stromal cotransporter homolog [Gallus gallus]	sp|Q9BY10|TSCOT_HUMAN	sp|Q9BY10|TSCOT_HUMAN Thymic stromal cotransporter homolog OS=Homo sapiens GN=SLC46A2 PE=2 SV=1	_	_	_	_	_	PF07690.13|MFS_1|Major Facilitator Superfamily|ENSGALT00000043789|m.11820:68-388
ENSGALG00000027355	9.558123576	4.402964738	1.116487803	5.63E-06	1.63E-05	up	yes	10.95788136	8.718100739	8.998388627	3.332508817	6.116500734	3.759884661	3	78230328	78231573	-	TPBG	protein_coding	GO:0051965|positive regulation of synapse assembly	GO:0005737|cytoplasm; GO:0005783|endoplasmic reticulum; GO:0005886|plasma membrane; GO:0009986|cell surface; GO:0016021|integral component of membrane	--	--	--	678	XP_001235286.3	XP_001235286.3 trophoblast glycoprotein [Gallus gallus]	sp|Q9Z0L0|TPBG_MOUSE	sp|Q9Z0L0|TPBG_MOUSE Trophoblast glycoprotein OS=Mus musculus GN=Tpbg PE=1 SV=3	_	_	_	_	_	PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000043299|m.12647:12-72;PF00560.30|LRR_1|Leucine Rich Repeat|ENSGALT00000043299|m.12647:38-59;PF00560.30|LRR_1|Leucine Rich Repeat|ENSGALT00000043299|m.12647:61-75
ENSGALG00000027423	0.302200811	0.115896027	1.310241525	0.001879835	0.003790095	up	yes	0.251995644	0.325535558	0.329071231	0.094787705	0.123392726	0.129507651	Z	53622721	53657488	+	SLC26A1	protein_coding	GO:0006821|chloride transport; GO:0008272|sulfate transport; GO:0015701|bicarbonate transport; GO:0019532|oxalate transport; GO:0042391|regulation of membrane potential; GO:0051453|regulation of intracellular pH; GO:1902476|chloride transmembrane transport	GO:0005887|integral component of plasma membrane; GO:0016323|basolateral plasma membrane	GO:0005254|chloride channel activity; GO:0008271|secondary active sulfate transmembrane transporter activity; GO:0015106|bicarbonate transmembrane transporter activity; GO:0015108|chloride transmembrane transporter activity; GO:0015116|sulfate transmembrane transporter activity; GO:0015301|anion:anion antiporter activity; GO:0019531|oxalate transmembrane transporter activity	"ko:K14700|SLC26A1,SAT1"	--	4391	XP_004949393.1	XP_004949393.1 sulfate anion transporter 1 isoform X1 [Gallus gallus]	sp|P45380|S26A1_RAT	sp|P45380|S26A1_RAT Sulfate anion transporter 1 OS=Rattus norvegicus GN=Slc26a1 PE=1 SV=1	9031.ENSGALP00000024770	annotation not avaliable	COG0659	KOG0236	_	PF00916.17|Sulfate_transp|Sulfate permease family|ENSGALT00000042951|m.11592:73-492;PF01740.18|STAS|STAS domain|ENSGALT00000042951|m.11592:543-698
ENSGALG00000027492	16.47818743	34.45014529	-1.063495974	6.98E-32	1.21E-30	down	yes	16.67637738	15.67139759	17.08678732	34.72121312	33.27139461	35.35782815	8	4306671	4368453	-	TEDC1	protein_coding	--	--	--	--	--	1346	XP_422217.3	XP_422217.3 tubulin epsilon and delta complex protein 1 isoform X1 [Gallus gallus]	sp|Q3UK37|CN080_MOUSE	sp|Q3UK37|CN080_MOUSE Uncharacterized protein C14orf80 homolog OS=Mus musculus PE=2 SV=2	9031.ENSGALP00000033336	chromosome 14 open reading frame 80	_	_	NOG43941	PF14970.3|DUF4509|Domain of unknown function (DUF4509)|ENSGALT00000045846|m.7009:42-227;PF14971.3|DUF4510|Domain of unknown function (DUF4510)|ENSGALT00000045846|m.7009:299-447
ENSGALG00000027512	3.351944825	1.203852797	1.46970257	2.21E-16	1.63E-15	up	yes	3.586867876	3.326816723	3.142149875	1.227766406	1.035572989	1.348218997	Z	50040254	50045272	-	C5orf30	protein_coding	GO:0010764|negative regulation of fibroblast migration; GO:0015031|protein transport; GO:0060271|cilium assembly; GO:1900016|negative regulation of cytokine production involved in inflammatory response	GO:0005737|cytoplasm; GO:0035869|ciliary transition zone	--	--	--	2938	XP_003643102.1	XP_003643102.1 UNC119-binding protein C5orf30 homolog [Gallus gallus]	sp|Q3ZBS1|CE030_BOVIN	sp|Q3ZBS1|CE030_BOVIN UNC119-binding protein C5orf30 homolog OS=Bos taurus PE=2 SV=1	9031.ENSGALP00000024594	chromosome 5 open reading frame 30	_	_	NOG38942	PF15435.3|UNC119_bdg|UNC119-binding protein C5orf30 homologue|ENSGALT00000043399|m.11523:3-201
ENSGALG00000027514	0.206334655	0.503103008	-1.245983691	0.002685838	0.005272621	down	yes	0.209351236	0.230244762	0.179407968	0.314988352	0.434687655	0.759633017	1	155434827	155487164	-	ENSGALG00000027514	protein_coding	GO:0008544|epidermis development; GO:0009612|response to mechanical stimulus; GO:0009790|embryo development; GO:0030216|keratinocyte differentiation; GO:0090263|positive regulation of canonical Wnt signaling pathway	GO:0005737|cytoplasm; GO:0016020|membrane; GO:0048471|perinuclear region of cytoplasm; GO:0070062|extracellular exosome	GO:0046872|metal ion binding	--	--	4027	XP_015132778.1	XP_015132778.1 sciellin isoform X1 [Gallus gallus]	sp|Q9EQG3|SCEL_MOUSE	sp|Q9EQG3|SCEL_MOUSE Sciellin OS=Mus musculus GN=Scel PE=1 SV=2	_	_	_	_	_	_
ENSGALG00000027520	2.459817055	0.909878477	1.424888994	1.57E-09	6.70E-09	up	yes	2.393071759	2.600001579	2.386377826	0.908332785	0.679723996	1.14157865	5	30262434	30276427	+	ENSGALG00000027520	protein_coding	--	--	GO:0004126|cytidine deaminase activity; GO:0047844|deoxycytidine deaminase activity	--	--	2422	XP_025006658.1	XP_025006658.1 fibrinogen-like protein 1-like protein [Gallus gallus]	sp|O93526|FGL1L_CHICK	sp|O93526|FGL1L_CHICK Fibrinogen-like protein 1-like protein OS=Gallus gallus PE=1 SV=2	_	_	_	_	_	"PF00147.15|Fibrinogen_C|Fibrinogen beta and gamma chains, C-terminal globular domain|ENSGALT00000042961|m.3306:53-267"
ENSGALG00000027562	3.983438771	1.700513372	1.223202211	1.74E-05	4.76E-05	up	yes	4.752529605	4.128444706	3.069342003	1.748793327	2.083913315	1.268833475	4	34666884	34667903	-	PURG	protein_coding	--	GO:0005634|nucleus	GO:0003677|DNA binding; GO:0003723|RNA binding	--	--	1020	XP_004941077.1	XP_004941077.1 purine-rich element-binding protein gamma isoform X1 [Gallus gallus]	sp|Q9UJV8|PURG_HUMAN	sp|Q9UJV8|PURG_HUMAN Purine-rich element-binding protein gamma OS=Homo sapiens GN=PURG PE=2 SV=1	_	_	_	_	_	PF04845.10|PurA|PurA ssDNA and RNA-binding protein|ENSGALT00000044895|m.198:48-313
ENSGALG00000027571	65.40852353	17.84876982	1.873066493	2.87E-131	8.46E-129	up	yes	62.29665073	68.47010274	65.45881711	18.17051826	17.82833555	17.54745566	1	48153914	48155235	+	ENSGALG00000027571	protein_coding	GO:0006334|nucleosome assembly; GO:0042742|defense response to bacterium	GO:0000786|nucleosome; GO:0005634|nucleus	GO:0003677|DNA binding; GO:0046982|protein heterodimerization activity	--	--	1322	XP_008691173.1	XP_008691173.1 PREDICTED: histone H2B type 1-B-like isoform X2 [Ursus maritimus]	sp|P0C1H3|H2B1_CHICK	sp|P0C1H3|H2B1_CHICK Histone H2B 1/2/3/4/6 OS=Gallus gallus GN=H2B-I PE=1 SV=2	_	_	_	_	_	PF00125.21|Histone|Core histone H2A/H2B/H3/H4|ENSGALT00000043224|m.1207:10-101;PF00808.20|CBFD_NFYB_HMF|Histone-like transcription factor (CBF/NF-Y) and archaeal histone|ENSGALT00000043224|m.1207:42-99
ENSGALG00000027587	3.51206631	1.422246847	1.29814191	8.61E-06	2.45E-05	up	yes	4.803331327	2.73918299	2.993684614	1.441761472	1.362411099	1.462567969	28	2646870	2647955	-	ENSGALG00000027587	protein_coding	--	--	GO:0019834|phospholipase A2 inhibitor activity	--	--	1086	XP_003642913.1	XP_003642913.1 leucine-rich alpha-2-glycoprotein [Gallus gallus]	sp|O93233|PLIB_GLOBS	sp|O93233|PLIB_GLOBS Phospholipase A2 inhibitor OS=Gloydius brevicaudus siniticus PE=1 SV=1	_	_	_	_	_	PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000043430|m.9952:105-165;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000043430|m.9952:155-213;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000043430|m.9952:177-237;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000043430|m.9952:203-261;PF00560.30|LRR_1|Leucine Rich Repeat|ENSGALT00000043430|m.9952:178-200;PF00560.30|LRR_1|Leucine Rich Repeat|ENSGALT00000043430|m.9952:203-220;PF00560.30|LRR_1|Leucine Rich Repeat|ENSGALT00000043430|m.9952:250-270;PF13516.3|LRR_6|Leucine Rich repeat|ENSGALT00000043430|m.9952:177-189;PF13516.3|LRR_6|Leucine Rich repeat|ENSGALT00000043430|m.9952:250-262
ENSGALG00000027629	3.540626806	1.436665147	1.295342705	1.26E-10	5.91E-10	up	yes	3.791215804	3.112623645	3.718040971	1.682237211	1.149249911	1.478508319	5	58219426	58234374	+	GNG2	protein_coding	GO:0007186|G protein-coupled receptor signaling pathway; GO:0007191|adenylate cyclase-activating dopamine receptor signaling pathway; GO:0008283|cell population proliferation; GO:0071380|cellular response to prostaglandin E stimulus; GO:0071870|cellular response to catecholamine stimulus	GO:0005834|heterotrimeric G-protein complex; GO:0016020|membrane; GO:0070062|extracellular exosome	GO:0003924|GTPase activity; GO:0031681|G-protein beta-subunit binding	ko:K07826|GNG2	ko04014|Ras signaling pathway; ko04062|Chemokine signaling pathway; ko04151|PI3K-Akt signaling pathway; ko04371|Apelin signaling pathway; ko04713|Circadian entrainment; ko04723|Retrograde endocannabinoid signaling; ko04724|Glutamatergic synapse; ko04725|Cholinergic synapse; ko04726|Serotonergic synapse; ko04727|GABAergic synapse; ko04728|Dopaminergic synapse; ko05032|Morphine addiction; ko05034|Alcoholism; ko05200|Pathways in cancer	2321	KQK76569.1	KQK76569.1 hypothetical protein AAES_134256 [Amazona aestiva]	sp|P63212|GBG2_BOVIN	sp|P63212|GBG2_BOVIN Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 OS=Bos taurus GN=GNG2 PE=1 SV=2	_	_	_	_	_	_
ENSGALG00000027645	0.492698773	1.083833138	-1.121626603	0.001272752	0.002642836	down	yes	0.704833802	0.265375956	0.50788656	1.038991456	0.851345642	1.361162316	7	25477633	25486533	-	ENSGALG00000027645	protein_coding	--	--	--	--	--	2766	XP_015145520.1	XP_015145520.1 leucine-zipper-like transcriptional regulator 1 isoform X1 [Gallus gallus]	_	_	_	_	_	_	_	"PF13964.3|Kelch_6|Kelch motif|ENSGALT00000053391|m.6510:23-61;PF13964.3|Kelch_6|Kelch motif|ENSGALT00000053391|m.6510:75-119;PF13854.3|Kelch_5|Kelch motif|ENSGALT00000053391|m.6510:20-54;PF13854.3|Kelch_5|Kelch motif|ENSGALT00000053391|m.6510:229-263;PF01344.22|Kelch_1|Kelch motif|ENSGALT00000053391|m.6510:23-61;PF01344.22|Kelch_1|Kelch motif|ENSGALT00000053391|m.6510:182-223;PF01344.22|Kelch_1|Kelch motif|ENSGALT00000053391|m.6510:233-275;PF13415.3|Kelch_3|Galactose oxidase, central domain|ENSGALT00000053391|m.6510:33-79;PF13418.3|Kelch_4|Galactose oxidase, central domain|ENSGALT00000053391|m.6510:23-69"
ENSGALG00000027707	0.092493945	0.524773396	-2.383389014	8.65E-06	2.46E-05	down	yes	0.056074235	0.16445471	0.05695289	0.569489987	0.524859331	0.479970869	Z	16626076	16634702	-	ESM1	protein_coding	GO:0001525|angiogenesis; GO:0001558|regulation of cell growth; GO:0002040|sprouting angiogenesis; GO:0008284|positive regulation of cell population proliferation; GO:1902204|positive regulation of hepatocyte growth factor receptor signaling pathway	GO:0005576|extracellular region	GO:0005171|hepatocyte growth factor receptor binding; GO:0005178|integrin binding; GO:0005520|insulin-like growth factor binding	--	--	2819	XP_428357.3	XP_428357.3 endothelial cell-specific molecule 1 [Gallus gallus]	sp|Q9QYY7|ESM1_MOUSE	sp|Q9QYY7|ESM1_MOUSE Endothelial cell-specific molecule 1 OS=Mus musculus GN=Esm1 PE=2 SV=1	59729.ENSTGUP00000002520	Endothelial cell-specific molecule 1 Precursor (ESM-1 secretory protein)(ESM-1) [Taeniopygia [...] 	_	KOG1218	_	PF00219.15|IGFBP|Insulin-like growth factor binding protein|ENSGALT00000043287|m.10788:28-83
ENSGALG00000027714	9.366517562	22.03525951	-1.23334435	0.000306409	0.000698159	down	yes	9.229989603	9.554027849	9.315535233	26.91894628	12.66912953	26.51770273	Z	63575834	63658645	-	ATG10	protein_coding	GO:0006497|protein lipidation; GO:0006914|autophagy; GO:0006983|ER overload response; GO:0015031|protein transport; GO:0016236|macroautophagy; GO:0031401|positive regulation of protein modification process; GO:0032446|protein modification by small protein conjugation	GO:0005622|intracellular; GO:0005829|cytosol	GO:0016874|ligase activity; GO:0019777|Atg12 transferase activity	"ko:K17888|ATG10L,ATG10"	ko04136|Autophagy - other; ko04138|Autophagy - yeast; ko04140|Autophagy - animal	2001	XP_424902.2	XP_424902.2 ubiquitin-like-conjugating enzyme ATG10 isoform X1 [Gallus gallus]	sp|Q9H0Y0|ATG10_HUMAN	sp|Q9H0Y0|ATG10_HUMAN Ubiquitin-like-conjugating enzyme ATG10 OS=Homo sapiens GN=ATG10 PE=1 SV=1	59729.ENSTGUP00000007145	Autophagy-related protein 10 (APG10-like) [Taeniopygia guttata]	_	KOG4741	_	"PF03987.12|Autophagy_act_C|Autophagocytosis associated protein, active-site domain|ENSGALT00000043880|m.11771:129-196"
ENSGALG00000027777	15.25234351	36.89841214	-1.273973169	8.63E-25	1.06E-23	down	yes	15.51002147	12.9477526	17.29925645	42.40140231	30.96828353	37.3255506	28	3014287	3018726	-	CNN2	protein_coding	GO:0031032|actomyosin structure organization	GO:0005856|cytoskeleton	GO:0003779|actin binding; GO:0005516|calmodulin binding	--	--	1471	NP_001135728.1	NP_001135728.1 calponin-2 [Gallus gallus]	sp|Q3SYU6|CNN2_BOVIN	sp|Q3SYU6|CNN2_BOVIN Calponin-2 OS=Bos taurus GN=CNN2 PE=2 SV=3	_	_	_	_	_	PF00402.15|Calponin|Calponin family repeat|ENSGALT00000051079|m.10083:186-209;PF00402.15|Calponin|Calponin family repeat|ENSGALT00000051079|m.10083:226-250;PF00402.15|Calponin|Calponin family repeat|ENSGALT00000051079|m.10083:265-288;PF00307.28|CH|Calponin homology (CH) domain|ENSGALT00000051079|m.10083:50-151
ENSGALG00000027786	9.338719735	30.77679284	-1.719470872	1.37E-55	5.82E-54	down	yes	10.11738089	9.489215197	8.409563113	34.84703493	28.47710865	29.00623493	18	9837554	9839601	+	SOCS3	protein_coding	GO:0006469|negative regulation of protein kinase activity; GO:0007259|receptor signaling pathway via JAK-STAT; GO:0016567|protein ubiquitination; GO:0019221|cytokine-mediated signaling pathway; GO:0040008|regulation of growth; GO:0043066|negative regulation of apoptotic process; GO:0046426|negative regulation of receptor signaling pathway via JAK-STAT; GO:0046627|negative regulation of insulin receptor signaling pathway	GO:0005737|cytoplasm	GO:0004860|protein kinase inhibitor activity	"ko:K04696|SOCS3,CIS3"	ko04120|Ubiquitin mediated proteolysis; ko04380|Osteoclast differentiation; ko04630|Jak-STAT signaling pathway; ko04668|TNF signaling pathway; ko04910|Insulin signaling pathway; ko04917|Prolactin signaling pathway; ko04920|Adipocytokine signaling pathway; ko04930|Type II diabetes mellitus; ko04931|Insulin resistance; ko04932|Non-alcoholic fatty liver disease (NAFLD); ko05160|Hepatitis C; ko05164|Influenza A; ko05168|Herpes simplex infection	1828	OWK54405.1	OWK54405.1 Suppressor of cytokine signaling 3 [Lonchura striata domestica]	sp|Q90X67|SOCS3_CHICK	sp|Q90X67|SOCS3_CHICK Suppressor of cytokine signaling 3 OS=Gallus gallus GN=SOCS3 PE=2 SV=1	9031.ENSGALP00000011628	Suppressor of cytokine signaling 3 (SOCS-3); SOCS family proteins form part of a classical n [...] 	_	KOG4566	_	PF00017.21|SH2|SH2 domain|ENSGALT00000043264|m.13124:46-127;PF07525.13|SOCS_box|SOCS box|ENSGALT00000043264|m.13124:171-203
ENSGALG00000027864	26.80388219	324.2246318	-3.595986178	0	0	down	yes	32.27367702	24.06951511	24.06845444	340.9189631	329.0780472	302.6768851	5	36403465	36406967	-	NFKBIA	protein_coding	GO:0048145|regulation of fibroblast proliferation	GO:0005737|cytoplasm	--	ko:K04734|NFKBIA	ko04024|cAMP signaling pathway; ko04062|Chemokine signaling pathway; ko04064|NF-kappa B signaling pathway; ko04210|Apoptosis; ko04380|Osteoclast differentiation; ko04620|Toll-like receptor signaling pathway; ko04621|NOD-like receptor signaling pathway; ko04622|RIG-I-like receptor signaling pathway; ko04623|Cytosolic DNA-sensing pathway; ko04624|Toll and Imd signaling pathway; ko04657|IL-17 signaling pathway; ko04658|Th1 and Th2 cell differentiation; ko04659|Th17 cell differentiation; ko04660|T cell receptor signaling pathway; ko04662|B cell receptor signaling pathway; ko04668|TNF signaling pathway; ko04722|Neurotrophin signaling pathway; ko04920|Adipocytokine signaling pathway; ko04931|Insulin resistance; ko05120|Epithelial cell signaling in Helicobacter pylori infection; ko05131|Shigellosis; ko05134|Legionellosis; ko05140|Leishmaniasis; ko05142|Chagas disease (American trypanosomiasis); ko05145|Toxoplasmosis; ko05160|Hepatitis C; ko05161|Hepatitis B; ko05162|Measles; ko05164|Influenza A; ko05166|HTLV-I infection; ko05168|Herpes simplex infection; ko05169|Epstein-Barr virus infection; ko05200|Pathways in cancer; ko05203|Viral carcinogenesis; ko05215|Prostate cancer; ko05220|Chronic myeloid leukemia; ko05222|Small cell lung cancer	1711	Q91974.1	Q91974.1 RecName: Full=NF-kappa-B inhibitor alpha; AltName: Full=I-kappa-B-alpha; Short=IkB-alpha; Short=IkappaBalpha; AltName: Full=REL-associated protein pp40	sp|Q91974|IKBA_CHICK	sp|Q91974|IKBA_CHICK NF-kappa-B inhibitor alpha OS=Gallus gallus GN=NFKBIA PE=2 SV=1	9031.ENSGALP00000016343	NF-kappa-B inhibitor alpha (I-kappa-B-alpha)(IkappaBalpha)(IkB-alpha)(REL-associated protein [...] 	COG0666	KOG0504	_	PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000045536|m.3402:94-167;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000045536|m.3402:151-238;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000045536|m.3402:139-167;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000045536|m.3402:170-190;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000045536|m.3402:208-238;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000045536|m.3402:242-273;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000045536|m.3402:134-177;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000045536|m.3402:200-250;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000045536|m.3402:208-237;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000045536|m.3402:242-270;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000045536|m.3402:139-189;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000045536|m.3402:210-251
ENSGALG00000027874	13.45484084	27.0506853	-1.007001199	2.71E-28	3.92E-27	down	yes	12.73255109	13.24848976	14.38348167	28.86842688	25.77838271	26.50524632	5	24667321	24669438	+	CHAC1	protein_coding	GO:0006750|glutathione biosynthetic process; GO:0006751|glutathione catabolic process; GO:0006986|response to unfolded protein; GO:0007219|Notch signaling pathway; GO:0010955|negative regulation of protein processing; GO:0022008|neurogenesis; GO:0045746|negative regulation of Notch signaling pathway; GO:0070059|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	GO:0005802|trans-Golgi network; GO:0005829|cytosol	GO:0003839|gamma-glutamylcyclotransferase activity; GO:0005112|Notch binding; GO:0016829|lyase activity	ko:K07232|chaC	--	1945	NP_001186585.1	NP_001186585.1 glutathione-specific gamma-glutamylcyclotransferase 1 [Gallus gallus]	sp|Q9BUX1|CHAC1_HUMAN	sp|Q9BUX1|CHAC1_HUMAN Glutathione-specific gamma-glutamylcyclotransferase 1 OS=Homo sapiens GN=CHAC1 PE=1 SV=2	9031.ENSGALP00000013867	"ChaC, cation transport regulator homolog 1 (E. coli)"	COG3703	KOG3182	_	PF04752.9|ChaC|ChaC-like protein|ENSGALT00000045646|m.3063:38-211
ENSGALG00000027905	18.28350802	77.71265176	-2.087003367	6.01E-85	5.42E-83	down	yes	20.4059993	18.23083901	16.21368575	67.02447556	89.65074887	76.46273086	2	5319910	5325537	+	CSRNP1	protein_coding	GO:0006915|apoptotic process; GO:0009791|post-embryonic development; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0048008|platelet-derived growth factor receptor signaling pathway; GO:0048705|skeletal system morphogenesis; GO:0060021|roof of mouth development; GO:0060325|face morphogenesis	GO:0005634|nucleus	"GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003700|DNA-binding transcription factor activity; GO:0043565|sequence-specific DNA binding"	ko:K17494|CSRNP	--	1619	XP_418530.3	XP_418530.3 cysteine/serine-rich nuclear protein 1 isoform X2 [Gallus gallus]	sp|Q96S65|CSRN1_HUMAN	sp|Q96S65|CSRN1_HUMAN Cysteine/serine-rich nuclear protein 1 OS=Homo sapiens GN=CSRNP1 PE=1 SV=2	9031.ENSGALP00000009690	AXIN1 up-regulated 1	_	KOG3813	_	PF16019.2|CSRNP_N|Cysteine/serine-rich nuclear protein N-terminus|ENSGALT00000044280|m.14693:1-186
ENSGALG00000027920	62.5870972	30.77198375	1.024009548	6.24E-17	4.77E-16	up	yes	71.29559711	58.09281419	58.3728803	32.05401431	28.40296667	31.85897027	13	11149867	11150817	-	ENSGALG00000027920	protein_coding	GO:0006836|neurotransmitter transport; GO:0031915|positive regulation of synaptic plasticity; GO:0043303|mast cell degranulation	GO:0005829|cytosol; GO:0042629|mast cell granule	GO:0019905|syntaxin binding	ko:K15294|CPLX1_2	ko04721|Synaptic vesicle cycle	405	NP_006641.1	NP_006641.1 complexin-2 [Homo sapiens]	sp|P84088|CPLX2_BOVIN	sp|P84088|CPLX2_BOVIN Complexin-2 OS=Bos taurus GN=CPLX2 PE=1 SV=1	8364.ENSXETP00000048290	Cplx2-prov protein	_	_	NOG128397	PF05835.9|Synaphin|Synaphin protein|ENSGALT00000046052|m.8751:1-132
ENSGALG00000027925	1.574397632	0.778072774	1.007533685	1.43E-05	3.93E-05	up	yes	1.941969308	1.29036731	1.490856279	0.701934321	0.87004731	0.76223669	2	32588887	32628505	-	HOXA3	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0007275|multicellular organism development"	GO:0005634|nucleus	GO:0003700|DNA-binding transcription factor activity; GO:0043565|sequence-specific DNA binding	ko:K09303|HOX_3	--	2547	XP_025002790.1	XP_025002790.1 homeobox protein Hox-A3 isoform X1 [Gallus gallus]	sp|O93353|HXA3_CHICK	sp|O93353|HXA3_CHICK Homeobox protein Hox-A3 OS=Gallus gallus GN=HOXA3 PE=2 SV=2	9031.ENSGALP00000017983	Homeobox protein Hox-A3 (Homeobox protein Hox-D3); Sequence-specific transcription factor wh [...] 	_	KOG0489	_	PF13293.3|DUF4074|Domain of unknown function (DUF4074)|ENSGALT00000045994|m.272:349-411;PF00046.26|Homeobox|Homeobox domain|ENSGALT00000045994|m.272:174-230
ENSGALG00000027961	0.373809879	0.16794176	1.108986716	0.02238893	0.036831237	up	yes	0.163636923	0.371934075	0.585858638	0.166189676	0.148850951	0.188784653	28	1074042	1081172	-	PCASP2	protein_coding	GO:0001923|B-1 B cell differentiation; GO:0002223|stimulatory C-type lectin receptor signaling pathway; GO:0002237|response to molecule of bacterial origin; GO:0002726|positive regulation of T cell cytokine production; GO:0006508|proteolysis; GO:0006952|defense response; GO:0007250|activation of NF-kappaB-inducing kinase activity; GO:0009620|response to fungus; GO:0031398|positive regulation of protein ubiquitination; GO:0032743|positive regulation of interleukin-2 production; GO:0038095|Fc-epsilon receptor signaling pathway; GO:0042098|T cell proliferation; GO:0042981|regulation of apoptotic process; GO:0043066|negative regulation of apoptotic process; GO:0043123|positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0045087|innate immune response; GO:0050852|T cell receptor signaling pathway; GO:0050856|regulation of T cell receptor signaling pathway; GO:0050870|positive regulation of T cell activation; GO:0051092|positive regulation of NF-kappaB transcription factor activity; GO:0051168|nuclear export; GO:0051259|protein complex oligomerization	GO:0001650|fibrillar center; GO:0005634|nucleus; GO:0005730|nucleolus; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0032449|CBM complex; GO:0032991|protein-containing complex; GO:0048471|perinuclear region of cytoplasm	GO:0002020|protease binding; GO:0004197|cysteine-type endopeptidase activity; GO:0004842|ubiquitin-protein transferase activity; GO:0008233|peptidase activity; GO:0042802|identical protein binding; GO:0043621|protein self-association	ko:K07369|MALT1	ko04064|NF-kappa B signaling pathway; ko04660|T cell receptor signaling pathway; ko04662|B cell receptor signaling pathway; ko05152|Tuberculosis	3214	NP_001026745.1	NP_001026745.1 paracaspase-2 [Gallus gallus]	sp|Q9UDY8|MALT1_HUMAN	sp|Q9UDY8|MALT1_HUMAN Mucosa-associated lymphoid tissue lymphoma translocation protein 1 OS=Homo sapiens GN=MALT1 PE=1 SV=1	_	_	_	_	_	PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000054370|m.9612:209-274;PF00656.19|Peptidase_C14|Caspase domain|ENSGALT00000054370|m.9612:320-514;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000054370|m.9612:214-272;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000054370|m.9612:208-278
ENSGALG00000027980	4.827585888	1.989297605	1.274794036	2.33E-06	7.11E-06	up	yes	5.096915809	4.191570772	5.194271082	1.787655401	2.206496452	1.973740961	6	30920353	30921117	+	NANOS1	protein_coding	"GO:0001558|regulation of cell growth; GO:0001894|tissue homeostasis; GO:0010608|posttranscriptional regulation of gene expression; GO:0010631|epithelial cell migration; GO:0016477|cell migration; GO:0017148|negative regulation of translation; GO:0098749|cerebellar neuron development; GO:1900153|positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"	GO:0005737|cytoplasm; GO:0048471|perinuclear region of cytoplasm	GO:0003723|RNA binding; GO:0008270|zinc ion binding; GO:0030371|translation repressor activity	"ko:K18741|NANOS1,NOS1"	--	765	POI27033.1	POI27033.1 hypothetical protein CIB84_009217 [Bambusicola thoracicus]	sp|Q80WY3|NANO1_MOUSE	sp|Q80WY3|NANO1_MOUSE Nanos homolog 1 OS=Mus musculus GN=Nanos1 PE=2 SV=2	13616.ENSMODP00000011646	nanos homolog 1 (Drosophila)	_	KOG4602	_	PF05741.10|zf-nanos|Nanos RNA binding domain|ENSGALT00000043482|m.5375:180-232
ENSGALG00000027981	2.968794457	6.236889138	-1.068409349	2.28E-09	9.55E-09	down	yes	2.780441835	3.171190351	2.954751184	6.998211384	5.810520515	5.901935513	1	182413608	182437196	-	AASDHPPT	protein_coding	GO:0015939|pantothenate metabolic process; GO:0019878|lysine biosynthetic process via aminoadipic acid	GO:0005829|cytosol; GO:0070062|extracellular exosome	GO:0000287|magnesium ion binding; GO:0008897|holo-[acyl-carrier-protein] synthase activity	"ko:K06133|LYS5,acpT"	ko00770|Pantothenate and CoA biosynthesis	1535	NP_001265017.1	NP_001265017.1 L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase [Gallus gallus]	sp|Q9NRN7|ADPPT_HUMAN	sp|Q9NRN7|ADPPT_HUMAN L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase OS=Homo sapiens GN=AASDHPPT PE=1 SV=2	9031.ENSGALP00000027688	aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase	COG2091	KOG0945	_	PF01648.17|ACPS|4'-phosphopantetheinyl transferase superfamily|ENSGALT00000045696|m.4590:121-239
ENSGALG00000028005	0.934366439	2.556076675	-1.442145603	3.43E-06	1.02E-05	down	yes	1.139266791	1.148553176	0.515279349	2.531023855	2.633052635	2.504153536	Z	43742056	43743702	+	GADD45G	protein_coding	GO:0000185|activation of MAPKKK activity; GO:0006915|apoptotic process; GO:0006950|response to stress; GO:0007275|multicellular organism development; GO:0030154|cell differentiation; GO:0043065|positive regulation of apoptotic process; GO:0046330|positive regulation of JNK cascade; GO:0051726|regulation of cell cycle; GO:1900745|positive regulation of p38MAPK cascade	GO:0005634|nucleus; GO:0005737|cytoplasm	--	ko:K04402|GADD45	ko04010|MAPK signaling pathway; ko04068|FoxO signaling pathway; ko04110|Cell cycle; ko04115|p53 signaling pathway; ko04210|Apoptosis	1480	NP_001038131.1	NP_001038131.1 growth arrest and DNA damage-inducible protein GADD45 gamma [Gallus gallus]	sp|Q2KIX1|GA45G_BOVIN	sp|Q2KIX1|GA45G_BOVIN Growth arrest and DNA damage-inducible protein GADD45 gamma OS=Bos taurus GN=GADD45G PE=2 SV=1	_	_	_	_	_	PF01248.23|Ribosomal_L7Ae|Ribosomal protein L7Ae/L30e/S12e/Gadd45 family|ENSGALT00000094271|m.11431:25-107
ENSGALG00000028015	11.88036129	50.84909858	-2.09671334	7.61E-52	2.93E-50	down	yes	11.24300309	12.46759904	11.93048174	63.66696838	43.62502185	45.25530552	9	13092443	13093885	-	HES1	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006351|transcription, DNA-templated; GO:0007219|Notch signaling pathway; GO:0007275|multicellular organism development; GO:0045892|negative regulation of transcription, DNA-templated; GO:0048635|negative regulation of muscle organ development"	GO:0005634|nucleus	GO:0003677|DNA binding; GO:0043425|bHLH transcription factor binding; GO:0046982|protein heterodimerization activity	ko:K06054|HES1	ko03460|Fanconi anemia pathway; ko04330|Notch signaling pathway; ko04950|Maturity onset diabetes of the young; ko05224|Breast cancer	942	XP_015147078.2	XP_015147078.2 transcription factor HES-1 [Gallus gallus]	sp|Q5PPM5|HES1_XENTR	sp|Q5PPM5|HES1_XENTR Transcription factor HES-1 OS=Xenopus tropicalis GN=hes1 PE=2 SV=1	59729.ENSTGUP00000009410	Transcription factor HES-4 (Hairy and enhancer of split 4)(bHLH factor Hes4) [Taeniopygia guttata]	_	KOG4304	_	PF07527.10|Hairy_orange|Hairy Orange|ENSGALT00000044381|m.8851:109-147;PF00010.23|HLH|Helix-loop-helix DNA-binding domain|ENSGALT00000044381|m.8851:35-92
ENSGALG00000028037	33.36969751	219.5902321	-2.717836793	2.69E-51	1.01E-49	down	yes	40.48103281	30.00783621	29.62022353	230.929042	233.8551921	193.9864622	5	38430793	38433702	+	FOS	protein_coding	GO:0007179|transforming growth factor beta receptor signaling pathway; GO:0007399|nervous system development; GO:0031668|cellular response to extracellular stimulus; GO:0034614|cellular response to reactive oxygen species; GO:0035914|skeletal muscle cell differentiation; GO:0035994|response to muscle stretch; GO:0042493|response to drug; GO:0045672|positive regulation of osteoclast differentiation; GO:0060395|SMAD protein signal transduction; GO:0071276|cellular response to cadmium ion; GO:0071277|cellular response to calcium ion	GO:0005654|nucleoplasm; GO:0005783|endoplasmic reticulum; GO:0005829|cytosol; GO:0032993|protein-DNA complex; GO:0035976|transcription factor AP-1 complex	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0000979|RNA polymerase II core promoter sequence-specific DNA binding; GO:0001102|RNA polymerase II activating transcription factor binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003682|chromatin binding; GO:0046982|protein heterodimerization activity; GO:0070412|R-SMAD binding"	ko:K04379|FOS	ko01522|Endocrine resistance; ko04010|MAPK signaling pathway; ko04024|cAMP signaling pathway; ko04210|Apoptosis; ko04380|Osteoclast differentiation; ko04620|Toll-like receptor signaling pathway; ko04657|IL-17 signaling pathway; ko04658|Th1 and Th2 cell differentiation; ko04659|Th17 cell differentiation; ko04660|T cell receptor signaling pathway; ko04662|B cell receptor signaling pathway; ko04668|TNF signaling pathway; ko04713|Circadian entrainment; ko04725|Cholinergic synapse; ko04728|Dopaminergic synapse; ko04915|Estrogen signaling pathway; ko04917|Prolactin signaling pathway; ko04921|Oxytocin signaling pathway; ko05031|Amphetamine addiction; ko05132|Salmonella infection; ko05133|Pertussis; ko05140|Leishmaniasis; ko05142|Chagas disease (American trypanosomiasis); ko05161|Hepatitis B; ko05166|HTLV-I infection; ko05168|Herpes simplex infection; ko05200|Pathways in cancer; ko05210|Colorectal cancer; ko05224|Breast cancer; ko05231|Choline metabolism in cancer; ko05323|Rheumatoid arthritis; ko05418|Fluid shear stress and atherosclerosis	2244	NP_990839.1	NP_990839.1 proto-oncogene c-Fos [Gallus gallus]	sp|P11939|FOS_CHICK	sp|P11939|FOS_CHICK Proto-oncogene c-Fos OS=Gallus gallus GN=FOS PE=1 SV=1	59729.ENSTGUP00000012581	Proto-oncogene protein c-fos (Cellular oncogene fos)(G0/G1 switch regulatory protein 7) [Tae [...] 	_	KOG1414	_	PF00170.18|bZIP_1|bZIP transcription factor|ENSGALT00000043488|m.3562:134-193;PF07716.12|bZIP_2|Basic region leucine zipper|ENSGALT00000043488|m.3562:136-188;PF03131.14|bZIP_Maf|bZIP Maf transcription factor|ENSGALT00000043488|m.3562:138-193
ENSGALG00000028148	12.02085591	34.65941137	-1.526924058	3.31E-101	4.21E-99	down	yes	11.93911856	12.16543639	11.95801279	33.96498851	35.82339986	34.18984574	21	559614	564059	-	PHF13	protein_coding	GO:0000278|mitotic cell cycle; GO:0007059|chromosome segregation; GO:0007076|mitotic chromosome condensation; GO:0016569|covalent chromatin modification; GO:0051301|cell division	GO:0005634|nucleus; GO:0005654|nucleoplasm	GO:0003682|chromatin binding; GO:0046872|metal ion binding	--	--	3067	NP_001274131.1	NP_001274131.1 PHD finger protein 13 [Gallus gallus]	sp|Q8K2W6|PHF13_MOUSE	sp|Q8K2W6|PHF13_MOUSE PHD finger protein 13 OS=Mus musculus GN=Phf13 PE=2 SV=2	_	_	_	_	_	PF00628.26|PHD|PHD-finger|ENSGALT00000076662|m.3732:623-667
ENSGALG00000028155	4.199338814	11.28053407	-1.423448187	6.92E-24	8.09E-23	down	yes	3.792938321	4.99825803	3.806820091	10.36290468	12.39604078	11.08265673	1	71872763	71904322	-	DUSP16	protein_coding	"GO:0000188|inactivation of MAPK activity; GO:0016311|dephosphorylation; GO:0045204|MAPK export from nucleus; GO:0045209|MAPK phosphatase export from nucleus, leptomycin B sensitive"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0031410|cytoplasmic vesicle	GO:0004721|phosphoprotein phosphatase activity; GO:0004725|protein tyrosine phosphatase activity; GO:0016791|phosphatase activity; GO:0017017|MAP kinase tyrosine/serine/threonine phosphatase activity	"ko:K04459|DUSP,MKP"	ko04010|MAPK signaling pathway	2056	XP_428887.4	XP_428887.4 dual specificity protein phosphatase 16 [Gallus gallus]	sp|Q9BY84|DUS16_HUMAN	sp|Q9BY84|DUS16_HUMAN Dual specificity protein phosphatase 16 OS=Homo sapiens GN=DUSP16 PE=1 SV=1	_	_	_	_	_	"PF00782.17|DSPc|Dual specificity phosphatase, catalytic domain|ENSGALT00000045814|m.2176:167-297;PF00581.17|Rhodanese|Rhodanese-like domain|ENSGALT00000045814|m.2176:13-131"
ENSGALG00000028250	14.29059901	5.402150625	1.401801682	2.20E-48	7.58E-47	up	yes	14.06231293	13.59931367	15.21017043	5.339347442	5.352004384	5.515100049	6	20008951	20032260	-	ANKRD22	protein_coding	--	--	--	--	--	2763	NP_001264334.1	NP_001264334.1 ankyrin repeat domain-containing protein 22 [Gallus gallus]	sp|Q5VYY1|ANR22_HUMAN	sp|Q5VYY1|ANR22_HUMAN Ankyrin repeat domain-containing protein 22 OS=Homo sapiens GN=ANKRD22 PE=2 SV=1	9031.ENSGALP00000010197	ankyrin repeat domain 22	COG0666	KOG0504	_	_
ENSGALG00000028253	22.62618039	6.960947532	1.699203866	3.89E-61	1.98E-59	up	yes	21.85930373	23.48180024	22.53743722	6.59699171	7.891326351	6.394524535	11	19748636	19750708	-	ATXN1L	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006351|transcription, DNA-templated; GO:0030198|extracellular matrix organization; GO:0048286|lung alveolus development; GO:1902035|positive regulation of hematopoietic stem cell proliferation"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005730|nucleolus; GO:0030425|dendrite	GO:0003677|DNA binding; GO:0003723|RNA binding	--	--	2073	XP_015148186.1	XP_015148186.1 ataxin-1-like [Gallus gallus]	sp|P0C7T5|ATX1L_HUMAN	sp|P0C7T5|ATX1L_HUMAN Ataxin-1-like OS=Homo sapiens GN=ATXN1L PE=1 SV=1	_	_	_	_	_	PF08517.9|AXH|Ataxin-1 and HBP1 module (AXH)|ENSGALT00000043828|m.7047:465-576
ENSGALG00000028340	22.76463055	6.240360368	1.865416374	6.07E-46	1.93E-44	up	yes	23.15490767	22.5471454	22.59183857	6.49225235	6.39355181	5.835276945	Z	81822686	81831505	-	ENSGALG00000028340	protein_coding	GO:0006839|mitochondrial transport	GO:0005743|mitochondrial inner membrane; GO:0016021|integral component of membrane	GO:0022857|transmembrane transporter activity	--	--	867	XP_021238090.1	XP_021238090.1 solute carrier family 25 member 51 isoform X1 [Numida meleagris]	sp|Q9H1U9|S2551_HUMAN	sp|Q9H1U9|S2551_HUMAN Solute carrier family 25 member 51 OS=Homo sapiens GN=SLC25A51 PE=2 SV=1	_	_	_	_	_	PF00153.24|Mito_carr|Mitochondrial carrier protein|ENSGALT00000044561|m.12120:21-101;PF00153.24|Mito_carr|Mitochondrial carrier protein|ENSGALT00000044561|m.12120:110-191;PF00153.24|Mito_carr|Mitochondrial carrier protein|ENSGALT00000044561|m.12120:199-287
ENSGALG00000028354	0.334087699	0.721016516	-1.087127685	0.011815612	0.020601448	down	yes	0.368653297	0.21237615	0.421233651	0.77258036	0.645690283	0.744778906	18	3085475	3106644	-	METRNL	protein_coding	GO:0009409|response to cold; GO:0014850|response to muscle activity; GO:0045444|fat cell differentiation; GO:0050728|negative regulation of inflammatory response; GO:0050873|brown fat cell differentiation; GO:0090336|positive regulation of brown fat cell differentiation; GO:0097009|energy homeostasis	GO:0005615|extracellular space; GO:0070062|extracellular exosome	GO:0005179|hormone activity	--	--	1695	XP_015150747.1	XP_015150747.1 meteorin-like protein [Gallus gallus]	sp|Q641Q3|METRL_HUMAN	sp|Q641Q3|METRL_HUMAN Meteorin-like protein OS=Homo sapiens GN=METRNL PE=2 SV=1	9031.ENSGALP00000002152	"meteorin, glial cell differentiation regulator-like"	_	_	NOG26140	_
ENSGALG00000028451	83.6269288	6.64502264	3.651624607	8.95E-167	4.32E-164	up	yes	93.61718312	70.6308395	86.63276379	6.997398235	6.164247403	6.773422282	11	2118766	2120425	-	MT4L	protein_coding	--	--	--	--	--	524	XP_010716357.1	XP_010716357.1 PREDICTED: metallothionein [Meleagris gallopavo]	_	_	_	_	_	_	_	_
ENSGALG00000028565	2.210550639	1.072774886	1.036184141	6.84E-22	7.15E-21	up	yes	2.463685916	2.145403357	2.022562643	1.034057282	1.087246698	1.097020678	13	2579691	2627833	+	PCDHGC3	protein_coding	GO:0007156|homophilic cell adhesion via plasma membrane adhesion molecules	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0005509|calcium ion binding	ko:K16497|PCDHGC	--	3938	XP_019475825.1	XP_019475825.1 PREDICTED: protocadherin gamma-C3 isoform X1 [Meleagris gallopavo]	sp|Q5DRA2|PCDGM_PANTR	sp|Q5DRA2|PCDGM_PANTR Protocadherin gamma-C5 OS=Pan troglodytes GN=PCDHGC5 PE=3 SV=1	8364.ENSXETP00000005820	annotation not avaliable	_	KOG3594	_	"PF00028.14|Cadherin|Cadherin domain|ENSGALT00000076739|m.8358:168-259;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000076739|m.8358:275-367;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000076739|m.8358:382-471;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000076739|m.8358:486-583;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000076739|m.8358:616-694;PF08266.9|Cadherin_2|Cadherin-like|ENSGALT00000076739|m.8358:56-138;PF15974.2|Cadherin_tail|Cadherin C-terminal cytoplasmic tail, catenin-binding region|ENSGALT00000076739|m.8358:835-951;PF16492.2|Cadherin_C_2|Cadherin cytoplasmic C-terminal|ENSGALT00000076739|m.8358:718-817"
ENSGALG00000028602	0.252036428	0.954875688	-1.880575694	7.14E-08	2.58E-07	down	yes	0.249298833	0.221954576	0.284855875	0.890846392	0.880328369	1.093452302	13	10211261	10285881	+	HMP19	protein_coding	GO:0007212|dopamine receptor signaling pathway; GO:0016197|endosomal transport; GO:0048268|clathrin coat assembly	GO:0005768|endosome; GO:0005769|early endosome; GO:0016021|integral component of membrane; GO:0030425|dendrite; GO:0030659|cytoplasmic vesicle membrane; GO:0032580|Golgi cisterna membrane; GO:0032585|multivesicular body membrane; GO:0032588|trans-Golgi network membrane	GO:0032051|clathrin light chain binding	--	--	2481	XP_013047340.1	XP_013047340.1 PREDICTED: neuron-specific protein family member 2 [Anser cygnoides domesticus]	sp|Q9Y328|NSG2_HUMAN	sp|Q9Y328|NSG2_HUMAN Neuron-specific protein family member 2 OS=Homo sapiens GN=NSG2 PE=2 SV=1	9031.ENSGALP00000034008	hypothetical LOC416212	_	_	NOG39845	PF06387.8|Calcyon|D1 dopamine receptor-interacting protein (calcyon)|ENSGALT00000044478|m.8620:1-180
ENSGALG00000028627	20.61440209	70.10369349	-1.76534394	1.38E-86	1.27E-84	down	yes	21.60785861	21.02584502	19.20950265	74.52643886	66.28470232	69.49993929	1	53094947	53127580	-	TIMP3	protein_coding	GO:0010033|response to organic substance; GO:0043086|negative regulation of catalytic activity; GO:0051045|negative regulation of membrane protein ectodomain proteolysis; GO:0070373|negative regulation of ERK1 and ERK2 cascade; GO:0071310|cellular response to organic substance; GO:1903984|positive regulation of TRAIL-activated apoptotic signaling pathway; GO:1904684|negative regulation of metalloendopeptidase activity	GO:0005604|basement membrane; GO:0005615|extracellular space; GO:0005634|nucleus; GO:0031012|extracellular matrix; GO:0070062|extracellular exosome	GO:0002020|protease binding; GO:0008191|metalloendopeptidase inhibitor activity; GO:0008270|zinc ion binding	ko:K16866|TIMP3	ko05205|Proteoglycans in cancer; ko05206|MicroRNAs in cancer	1051	NP_990818.1	NP_990818.1 metalloproteinase inhibitor 3 precursor [Gallus gallus]	sp|P26652|TIMP3_CHICK	sp|P26652|TIMP3_CHICK Metalloproteinase inhibitor 3 OS=Gallus gallus GN=TIMP3 PE=1 SV=2	9031.ENSGALP00000020494	Metalloproteinase inhibitor 3 Precursor (Tissue inhibitor of metalloproteinases 3)(TIMP-3)(2 [...] 	_	KOG4745	_	PF00965.14|TIMP|Tissue inhibitor of metalloproteinase|ENSGALT00000046125|m.1508:23-195
ENSGALG00000028658	0.828797026	0.147196098	2.415756344	1.30E-06	4.11E-06	up	yes	0.839921718	0.985330133	0.661139228	0.063187006	0.232530179	0.145871108	1	182437515	182450316	+	KBTBD3	protein_coding	GO:0016567|protein ubiquitination	GO:0031463|Cul3-RING ubiquitin ligase complex	--	ko:K10471|KBTBD3	--	1882	XP_417170.1	XP_417170.1 kelch repeat and BTB domain-containing protein 3 [Gallus gallus]	sp|Q8NAB2|KBTB3_HUMAN	sp|Q8NAB2|KBTB3_HUMAN Kelch repeat and BTB domain-containing protein 3 OS=Homo sapiens GN=KBTBD3 PE=2 SV=2	9031.ENSGALP00000027690	kelch repeat and BTB (POZ) domain containing 3	_	KOG4441	_	PF00651.28|BTB|BTB/POZ domain|ENSGALT00000045225|m.4591:39-145;PF07707.12|BACK|BTB And C-terminal Kelch|ENSGALT00000045225|m.4591:151-251;PF01344.22|Kelch_1|Kelch motif|ENSGALT00000045225|m.4591:389-437;PF01344.22|Kelch_1|Kelch motif|ENSGALT00000045225|m.4591:540-583
ENSGALG00000028709	0.979895436	3.957524082	-2.002890935	3.62E-09	1.49E-08	down	yes	0.386487206	1.637264808	0.915934295	3.909011544	3.872308361	4.091252341	3	95000776	95059703	+	RNF144A	protein_coding	GO:0000209|protein polyubiquitination; GO:0006511|ubiquitin-dependent protein catabolic process; GO:0032436|positive regulation of proteasomal ubiquitin-dependent protein catabolic process	GO:0000151|ubiquitin ligase complex; GO:0005794|Golgi apparatus; GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0030659|cytoplasmic vesicle membrane; GO:0043231|intracellular membrane-bounded organelle	GO:0031624|ubiquitin conjugating enzyme binding; GO:0046872|metal ion binding; GO:0061630|ubiquitin protein ligase activity	ko:K11975|RNF144	--	1227	OPJ73536.1	OPJ73536.1 E3 ubiquitin-protein ligase RNF144A [Patagioenas fasciata monilis]	sp|Q925F3|R144A_MOUSE	sp|Q925F3|R144A_MOUSE E3 ubiquitin-protein ligase RNF144A OS=Mus musculus GN=Rnf144a PE=1 SV=1	_	_	_	_	_	"PF01485.18|IBR|IBR domain, a half RING-finger domain|ENSGALT00000044995|m.12926:91-156;PF01485.18|IBR|IBR domain, a half RING-finger domain|ENSGALT00000044995|m.12926:177-218"
ENSGALG00000028774	114.298478	42.76738066	1.418012357	8.04E-46	2.53E-44	up	yes	107.7240044	110.8342214	124.3372082	47.2588727	38.99233359	42.05093568	25	464699	466723	-	S100A10	protein_coding	GO:0001765|membrane raft assembly; GO:0006900|vesicle budding from membrane; GO:0043547|positive regulation of GTPase activity; GO:0051099|positive regulation of binding; GO:0051290|protein heterotetramerization; GO:0051496|positive regulation of stress fiber assembly; GO:0051894|positive regulation of focal adhesion assembly; GO:0072659|protein localization to plasma membrane; GO:1900026|positive regulation of substrate adhesion-dependent cell spreading	GO:0019897|extrinsic component of plasma membrane; GO:0045121|membrane raft; GO:0070062|extracellular exosome	GO:0005509|calcium ion binding; GO:0042803|protein homodimerization activity; GO:0044325|ion channel binding	ko:K17274|S100A10	--	450	OXB71077.1	"OXB71077.1 hypothetical protein H355_010457, partial [Colinus virginianus]"	sp|P27003|S10AA_CHICK	sp|P27003|S10AA_CHICK Protein S100-A10 OS=Gallus gallus GN=S100A10 PE=3 SV=2	_	_	_	_	_	_
ENSGALG00000028876	8.079803941	1.972790566	2.02857244	1.38E-34	2.70E-33	up	yes	8.05719218	9.707817756	6.474401887	1.96810587	2.030479641	1.919786186	14	1313219	1317821	-	SNN	protein_coding	--	GO:0005741|mitochondrial outer membrane; GO:0016021|integral component of membrane	GO:0046872|metal ion binding	--	--	2093	XP_013795657.1	XP_013795657.1 PREDICTED: stannin isoform X1 [Apteryx australis mantelli]	sp|Q17Q87|SNN_BOVIN	sp|Q17Q87|SNN_BOVIN Stannin OS=Bos taurus GN=SNN PE=3 SV=1	9031.ENSGALP00000040319	stannin	_	_	NOG47301	_
ENSGALG00000028880	98.03766434	36.78600694	1.413934048	3.44E-61	1.76E-59	up	yes	108.6753713	85.81912596	99.61849578	37.77376028	36.43709878	36.14716176	25	3549515	3553094	+	FDPS	protein_coding	GO:0006695|cholesterol biosynthetic process; GO:0033384|geranyl diphosphate biosynthetic process; GO:0045337|farnesyl diphosphate biosynthetic process	GO:0005737|cytoplasm	GO:0004161|dimethylallyltranstransferase activity; GO:0004337|geranyltranstransferase activity; GO:0046872|metal ion binding	ko:K00787|FDPS	ko00900|Terpenoid backbone biosynthesis; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko01130|Biosynthesis of antibiotics; ko05164|Influenza A; ko05166|HTLV-I infection	1328	XP_015154133.1	XP_015154133.1 farnesyl pyrophosphate synthase isoform X1 [Gallus gallus]	sp|P08836|FPPS_CHICK	sp|P08836|FPPS_CHICK Farnesyl pyrophosphate synthase OS=Gallus gallus GN=FDPS PE=1 SV=2	_	_	_	_	_	PF00348.14|polyprenyl_synt|Polyprenyl synthetase|ENSGALT00000044496|m.7269:45-309
ENSGALG00000028942	1.509107531	4.893170663	-1.690490982	1.77E-19	1.61E-18	down	yes	1.44288557	1.435755293	1.64868173	4.77803973	4.646770033	5.254702225	5	53091329	53095078	+	ZBTB25	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated; GO:0010467|gene expression"	GO:0005654|nucleoplasm; GO:0005737|cytoplasm	GO:0003677|DNA binding; GO:0046872|metal ion binding	ko:K10504|ZBTB25	--	2045	XP_004936487.1	XP_004936487.1 zinc finger and BTB domain-containing protein 25 [Gallus gallus]	sp|A1YEX3|ZBT25_GORGO	sp|A1YEX3|ZBT25_GORGO Zinc finger and BTB domain-containing protein 25 OS=Gorilla gorilla gorilla GN=ZBTB25 PE=3 SV=1	_	_	_	_	_	PF00651.28|BTB|BTB/POZ domain|ENSGALT00000044533|m.3987:14-114
ENSGALG00000028960	2.187741146	0.930600423	1.224367586	1.18E-07	4.19E-07	up	yes	2.38401241	1.92599293	2.253218099	0.87183245	1.073822111	0.846146709	1	196009412	196013046	+	NEU3	protein_coding	GO:0005975|carbohydrate metabolic process; GO:0006687|glycosphingolipid metabolic process; GO:0006689|ganglioside catabolic process; GO:0009313|oligosaccharide catabolic process	GO:0005737|cytoplasm; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0043231|intracellular membrane-bounded organelle	GO:0004308|exo-alpha-sialidase activity; GO:0016997|alpha-sialidase activity; GO:0052794|exo-alpha-(2->3)-sialidase activity; GO:0052795|exo-alpha-(2->6)-sialidase activity; GO:0052796|exo-alpha-(2->8)-sialidase activity	ko:K12357|NEU2_3_4	ko00511|Other glycan degradation; ko00600|Sphingolipid metabolism	2387	XP_015136494.1	XP_015136494.1 sialidase-3 isoform X1 [Gallus gallus]	sp|Q9UQ49|NEUR3_HUMAN	sp|Q9UQ49|NEUR3_HUMAN Sialidase-3 OS=Homo sapiens GN=NEU3 PE=1 SV=1	9031.ENSGALP00000021857	sialidase 3 (membrane sialidase)	_	_	NOG84455	PF13088.3|BNR_2|BNR repeat-like domain|ENSGALT00000086832|m.4891:62-292
ENSGALG00000028982	1.430342418	3.421200615	-1.25230165	2.83E-08	1.07E-07	down	yes	1.54233176	1.453935839	1.294759654	3.587429082	3.161971219	3.514201544	3	94980479	94986009	-	CMPK2	protein_coding	GO:0006165|nucleoside diphosphate phosphorylation; GO:0006227|dUDP biosynthetic process; GO:0006233|dTDP biosynthetic process; GO:0006235|dTTP biosynthetic process; GO:0009142|nucleoside triphosphate biosynthetic process; GO:0071222|cellular response to lipopolysaccharide	GO:0005739|mitochondrion	GO:0004127|cytidylate kinase activity; GO:0004550|nucleoside diphosphate kinase activity; GO:0004798|thymidylate kinase activity; GO:0005524|ATP binding; GO:0033862|UMP kinase activity	ko:K13809|CMPK2	ko00240|Pyrimidine metabolism; ko01100|Metabolic pathways	1674	XP_015140431.2	"XP_015140431.2 UMP-CMP kinase 2, mitochondrial [Gallus gallus]"	sp|Q5EBM0|CMPK2_HUMAN	"sp|Q5EBM0|CMPK2_HUMAN UMP-CMP kinase 2, mitochondrial OS=Homo sapiens GN=CMPK2 PE=1 SV=3"	_	_	_	_	_	PF02223.14|Thymidylate_kin|Thymidylate kinase|ENSGALT00000043751|m.12921:30-209;PF13671.3|AAA_33|AAA domain|ENSGALT00000043751|m.12921:27-185;PF01712.16|dNK|Deoxynucleoside kinase|ENSGALT00000043751|m.12921:29-192
ENSGALG00000029001	8.608637363	4.124429095	1.059771664	5.28E-10	2.34E-09	up	yes	8.640660914	7.763897165	9.421354009	4.779660218	3.668625531	3.925001535	23	3716700	3719411	+	YRDC	protein_coding	GO:0002949|tRNA threonylcarbamoyladenosine modification; GO:0006450|regulation of translational fidelity; GO:0051051|negative regulation of transport	GO:0005737|cytoplasm; GO:0005739|mitochondrion; GO:0016020|membrane	GO:0000049|tRNA binding; GO:0003725|double-stranded RNA binding; GO:0016779|nucleotidyltransferase activity	--	--	1229	XP_015153269.1	"XP_015153269.1 yrdC domain-containing protein, mitochondrial isoform X1 [Gallus gallus]"	sp|Q86U90|YRDC_HUMAN	"sp|Q86U90|YRDC_HUMAN YrdC domain-containing protein, mitochondrial OS=Homo sapiens GN=YRDC PE=1 SV=1"	9031.ENSGALP00000002506	yrdC domain containing (E. coli)	COG0009	KOG3051	_	PF01300.15|Sua5_yciO_yrdC|Telomere recombination|ENSGALT00000100422|m.5517:116-295
ENSGALG00000029002	1.069313181	0.498118531	1.086876562	0.001068649	0.002240584	up	yes	1.114447739	1.176644232	0.916847572	0.503036998	0.352608006	0.63871059	1	129834286	129858036	-	XG	protein_coding	--	--	--	--	--	2364	XP_015133218.1	XP_015133218.1 glycoprotein Xg [Gallus gallus]	_	_	9031.ENSGALP00000026834	Xg blood group	_	_	NOG124417	PF12301.5|CD99L2|CD99 antigen like protein 2|ENSGALT00000042795|m.3554:25-161
ENSGALG00000029140	3.566050096	1.530083325	1.215358538	0.013492382	0.023233355	up	yes	3.790725835	3.057299822	3.85012463	1.283287189	2.648618842	0.658343944	25	2633647	2636309	+	CRABP2	protein_coding	GO:0048385|regulation of retinoic acid receptor signaling pathway	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005783|endoplasmic reticulum	GO:0001972|retinoic acid binding; GO:0005215|transporter activity; GO:0016918|retinal binding; GO:0019841|retinol binding	ko:K17289|CRABP2	--	417	XP_003213835.1	XP_003213835.1 PREDICTED: cellular retinoic acid-binding protein 2 [Meleagris gallopavo]	sp|Q5PXY7|RABP2_BOVIN	sp|Q5PXY7|RABP2_BOVIN Cellular retinoic acid-binding protein 2 OS=Bos taurus GN=CRABP2 PE=2 SV=3	_	_	_	_	_	PF00061.20|Lipocalin|Lipocalin / cytosolic fatty-acid binding protein family|ENSGALT00000045442|m.6976:5-137;PF14651.3|Lipocalin_7|Lipocalin / cytosolic fatty-acid binding protein family|ENSGALT00000045442|m.6976:4-95
ENSGALG00000029151	0.704159823	0.146224013	2.192630748	7.26E-07	2.36E-06	up	yes	0.69961613	0.864702574	0.548160764	0.105263736	0.229262087	0.104146216	10	3060233	3063299	-	ISLR2	protein_coding	GO:0045773|positive regulation of axon extension	GO:0005886|plasma membrane; GO:0009986|cell surface; GO:0016021|integral component of membrane	--	--	--	2636	NP_001038132.1	NP_001038132.1 immunoglobulin superfamily containing leucine-rich repeat protein 2 precursor [Gallus gallus]	sp|Q6UXK2|ISLR2_HUMAN	sp|Q6UXK2|ISLR2_HUMAN Immunoglobulin superfamily containing leucine-rich repeat protein 2 OS=Homo sapiens GN=ISLR2 PE=2 SV=1	_	_	_	_	_	PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000044983|m.5241:113-173;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000044983|m.5241:186-244;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000044983|m.5241:309-403;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000044983|m.5241:304-390;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000044983|m.5241:306-400;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000044983|m.5241:114-235
ENSGALG00000029175	2.520899303	6.39370439	-1.339256603	5.36E-14	3.32E-13	down	yes	2.77720163	2.554563975	2.230932302	5.270680415	7.558803928	6.351628827	1	142513096	142555148	+	EFNB2	protein_coding	GO:0001945|lymph vessel development; GO:0002042|cell migration involved in sprouting angiogenesis; GO:0007155|cell adhesion; GO:0007267|cell-cell signaling; GO:0007411|axon guidance; GO:0008284|positive regulation of cell population proliferation; GO:0009653|anatomical structure morphogenesis; GO:0009887|animal organ morphogenesis; GO:0010839|negative regulation of keratinocyte proliferation; GO:0010977|negative regulation of neuron projection development; GO:0031295|T cell costimulation; GO:0048013|ephrin receptor signaling pathway; GO:0048845|venous blood vessel morphogenesis; GO:0050920|regulation of chemotaxis; GO:0072178|nephric duct morphogenesis; GO:1901216|positive regulation of neuron death; GO:1903849|positive regulation of aorta morphogenesis; GO:2000727|positive regulation of cardiac muscle cell differentiation	GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0005925|focal adhesion	GO:0001618|virus receptor activity; GO:0046875|ephrin receptor binding	ko:K05463|EFNB	ko04360|Axon guidance	2087	NP_990155.1	NP_990155.1 ephrin-B2 precursor [Gallus gallus]	sp|P52799|EFNB2_HUMAN	sp|P52799|EFNB2_HUMAN Ephrin-B2 OS=Homo sapiens GN=EFNB2 PE=1 SV=1	9031.ENSGALP00000029571	ephrin-B2 	_	KOG3858	_	PF00812.14|Ephrin|Ephrin|ENSGALT00000099013|m.3922:33-166
ENSGALG00000029195	0.34809597	0.901565622	-1.348000236	0.000335624	0.000760567	down	yes	0.460184184	0.303666699	0.280437025	1.029929811	0.809905175	0.86486188	13	18677413	18699290	+	STK32A	protein_coding	GO:0018105|peptidyl-serine phosphorylation; GO:0035556|intracellular signal transduction	GO:0005622|intracellular; GO:0005886|plasma membrane	GO:0004674|protein serine/threonine kinase activity; GO:0005524|ATP binding; GO:0046872|metal ion binding	"ko:K08793|STK32,YANK"	--	2290	NP_001020782.1	NP_001020782.1 serine/threonine-protein kinase 32A [Gallus gallus]	sp|Q8BGW6|ST32A_MOUSE	sp|Q8BGW6|ST32A_MOUSE Serine/threonine-protein kinase 32A OS=Mus musculus GN=Stk32a PE=2 SV=1	_	_	_	_	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000052167|m.9142:23-280;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000052167|m.9142:24-270;PF14531.3|Kinase-like|Kinase-like|ENSGALT00000052167|m.9142:111-268
ENSGALG00000029264	10.34895505	21.7752937	-1.072476084	3.25E-22	3.47E-21	down	yes	9.627018535	10.25376147	11.16608514	21.71221148	20.76079055	22.85287906	2	118380780	118403137	+	PI15	protein_coding	GO:0007275|multicellular organism development	GO:0070062|extracellular exosome	GO:0030414|peptidase inhibitor activity	--	--	1330	NP_989665.1	NP_989665.1 peptidase inhibitor 15 precursor [Gallus gallus]	sp|Q98ST6|PI15_CHICK	sp|Q98ST6|PI15_CHICK Peptidase inhibitor 15 OS=Gallus gallus GN=PI15 PE=2 SV=1	_	_	_	_	_	PF00188.23|CAP|Cysteine-rich secretory protein family|ENSGALT00000065508|m.1953:71-211
ENSGALG00000029322	4.589310515	2.219502436	1.044695826	3.91E-07	1.31E-06	up	yes	4.491803847	4.204333382	5.071794315	1.977172625	2.78443073	1.896903953	19	10039242	10045919	+	FBXO39	protein_coding	GO:0031146|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	GO:0019005|SCF ubiquitin ligase complex	--	ko:K10314|FBXO39	--	1654	XP_024997883.1	XP_024997883.1 F-box only protein 39 isoform X4 [Gallus gallus]	sp|Q32LM4|FBX39_BOVIN	sp|Q32LM4|FBX39_BOVIN F-box only protein 39 OS=Bos taurus GN=FBXO39 PE=2 SV=1	9031.ENSGALP00000038070	"PREDICTED: Gallus gallus hypothetical protein LOC772529 (LOC776097), mRNA"	_	KOG1947	_	PF12937.4|F-box-like|F-box-like|ENSGALT00000073448|m.14272:12-57;PF00646.30|F-box|F-box domain|ENSGALT00000073448|m.14272:11-53
ENSGALG00000029324	27.30131093	13.30759661	1.036164818	1.99E-16	1.47E-15	up	yes	26.81025565	27.10086803	27.99280912	13.79577259	11.70610736	14.42090988	11	313945	323201	-	ENSGALG00000029324	protein_coding	--	GO:0005887|integral component of plasma membrane; GO:0016323|basolateral plasma membrane	GO:0015179|L-amino acid transmembrane transporter activity; GO:0015297|antiporter activity	ko:K13872|SLC7A6	--	737	XP_015729032.1	XP_015729032.1 PREDICTED: Y+L amino acid transporter 2 isoform X1 [Coturnix japonica]	sp|Q59I64|YLAT2_DANRE	sp|Q59I64|YLAT2_DANRE Y+L amino acid transporter 2 OS=Danio rerio GN=slc7a6 PE=2 SV=1	9031.ENSGALP00000001257	Putative uncharacterized protein 	COG0531	KOG1287	_	PF13520.3|AA_permease_2|Amino acid permease|ENSGALT00000089321|m.6090:48-176;PF00324.18|AA_permease|Amino acid permease|ENSGALT00000089321|m.6090:57-154
ENSGALG00000029378	9.864869696	23.58674308	-1.25675413	4.63E-38	1.08E-36	down	yes	8.2992197	11.22878591	10.06660348	21.82969664	25.75866412	23.17186847	2	48649047	48868823	-	ITGA9	protein_coding	GO:0007155|cell adhesion; GO:0007229|integrin-mediated signaling pathway; GO:0030198|extracellular matrix organization; GO:0030593|neutrophil chemotaxis; GO:0042060|wound healing	GO:0005886|plasma membrane; GO:0008305|integrin complex; GO:0009925|basal plasma membrane; GO:0034679|integrin alpha9-beta1 complex	GO:0005518|collagen binding; GO:0043236|laminin binding; GO:0046872|metal ion binding	ko:K06585|ITGA9	ko04151|PI3K-Akt signaling pathway; ko04510|Focal adhesion; ko04512|ECM-receptor interaction; ko04514|Cell adhesion molecules (CAMs); ko04810|Regulation of actin cytoskeleton; ko05410|Hypertrophic cardiomyopathy (HCM); ko05412|Arrhythmogenic right ventricular cardiomyopathy (ARVC); ko05414|Dilated cardiomyopathy	5295	NP_001012876.1	NP_001012876.1 integrin alpha-9 precursor [Gallus gallus]	sp|Q13797|ITA9_HUMAN	sp|Q13797|ITA9_HUMAN Integrin alpha-9 OS=Homo sapiens GN=ITGA9 PE=1 SV=2	9031.ENSGALP00000019958	"integrin, alpha 9 "	_	KOG3637	_	"PF08441.9|Integrin_alpha2|Integrin alpha|ENSGALT00000053949|m.684:453-892;PF01839.20|FG-GAP|FG-GAP repeat|ENSGALT00000053949|m.684:298-334;PF01839.20|FG-GAP|FG-GAP repeat|ENSGALT00000053949|m.684:361-393;PF13517.3|VCBS|Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella|ENSGALT00000053949|m.684:306-377"
ENSGALG00000029390	16.64909628	7.150878629	1.218101619	2.56E-12	1.38E-11	up	yes	16.26901499	13.91653191	19.76174192	6.340085218	7.91249423	7.200056438	15	5354761	5356086	-	C15H12ORF65	protein_coding	GO:0070126|mitochondrial translational termination; GO:0072344|rescue of stalled ribosome	GO:0005762|mitochondrial large ribosomal subunit	"GO:0004045|aminoacyl-tRNA hydrolase activity; GO:0016150|translation release factor activity, codon nonspecific"	--	--	719	NP_001239017.1	"NP_001239017.1 probable peptide chain release factor C12orf65 homolog, mitochondrial [Gallus gallus]"	sp|A5WUX7|CL065_DANRE	"sp|A5WUX7|CL065_DANRE Probable peptide chain release factor C12orf65 homolog, mitochondrial OS=Danio rerio GN=si:ch211-275j6.5 PE=3 SV=1"	9031.ENSGALP00000005389	annotation not avaliable	COG1186	KOG2726	_	PF00472.17|RF-1|RF-1 domain|ENSGALT00000083825|m.10481:79-180
ENSGALG00000029445	8.482337803	17.89430794	-1.076073091	1.44E-14	9.26E-14	down	yes	9.228382837	7.6393239	8.579306671	17.05759618	16.44368511	20.18164253	18	10523477	10528464	-	ENSGALG00000029445	protein_coding	GO:0006633|fatty acid biosynthetic process	GO:0016021|integral component of membrane	GO:0016491|oxidoreductase activity	ko:K12419|FADS6	--	1062	XP_426241.2	XP_426241.2 fatty acid desaturase 6 [Gallus gallus]	sp|A2VE15|FADS6_BOVIN	sp|A2VE15|FADS6_BOVIN Fatty acid desaturase 6 OS=Bos taurus GN=FADS6 PE=2 SV=1	9031.ENSGALP00000012595	"fatty acid desaturase domain family, member 6"	_	_	NOG74273	PF00487.21|FA_desaturase|Fatty acid desaturase|ENSGALT00000059705|m.13299:78-322
ENSGALG00000029494	3.347813021	1.591603166	1.068005165	0.01767975	0.02968655	up	yes	3.60387166	2.369014056	4.070553346	1.028378466	1.572764766	2.173666267	23	6070881	6072078	+	BGLAP	protein_coding	GO:0030500|regulation of bone mineralization; GO:0031214|biomineral tissue development	GO:0005576|extracellular region	GO:0005509|calcium ion binding	--	--	424	NP_990718.2	NP_990718.2 osteocalcin preproprotein [Gallus gallus]	sp|P02822|OSTCN_CHICK	sp|P02822|OSTCN_CHICK Osteocalcin OS=Gallus gallus GN=BGLAP PE=1 SV=2	59729.ENSTGUP00000003851	bone gamma-carboxyglutamate (gla) protein	_	_	NOG72046	_
ENSGALG00000029500	6113.259158	2084.091128	1.552518804	1.27E-13	7.61E-13	up	yes	7546.418941	5578.899196	5214.459337	2409.756402	1969.790978	1872.726006	MT	13071	14888	+	ND5	protein_coding	GO:0042773|ATP synthesis coupled electron transport	GO:0005747|mitochondrial respiratory chain complex I; GO:0016021|integral component of membrane	GO:0008137|NADH dehydrogenase (ubiquinone) activity	ko:K03883|ND5	ko00190|Oxidative phosphorylation; ko01100|Metabolic pathways; ko04723|Retrograde endocannabinoid signaling; ko05012|Parkinson's disease	1818	NP_006925.1	NP_006925.1 NADH dehydrogenase subunit 5 (mitochondrion) [Gallus gallus]	sp|P18940|NU5M_CHICK	sp|P18940|NU5M_CHICK NADH-ubiquinone oxidoreductase chain 5 OS=Gallus gallus GN=MT-ND5 PE=3 SV=1	9031.ENSGALP00000034622	NADH-ubiquinone oxidoreductase chain 5 (EC 1.6.5.3)(NADH dehydrogenase subunit 5); Core subu [...] 	COG1009	KOG4668	_	_
ENSGALG00000029596	4.460539046	1.710546119	1.377582234	9.04E-16	6.38E-15	up	yes	5.192528455	4.546687899	3.642400784	1.594846614	1.861560282	1.675231461	2	137356485	137374399	-	HAS2	protein_coding	GO:0001570|vasculogenesis; GO:0007155|cell adhesion; GO:0030213|hyaluronan biosynthetic process; GO:0035810|positive regulation of urine volume; GO:0036302|atrioventricular canal development; GO:0045226|extracellular polysaccharide biosynthetic process; GO:0070295|renal water absorption; GO:0085029|extracellular matrix assembly; GO:0090500|endocardial cushion to mesenchymal transition	GO:0005887|integral component of plasma membrane	GO:0050501|hyaluronan synthase activity	ko:K00752|hasA	--	2821	NP_990137.2	NP_990137.2 hyaluronan synthase 2 [Gallus gallus]	sp|O57424|HYAS2_CHICK	sp|O57424|HYAS2_CHICK Hyaluronan synthase 2 OS=Gallus gallus GN=HAS2 PE=2 SV=2	9031.ENSGALP00000026394	Hyaluronan synthase 2 (EC 2.4.1.212)(Hyaluronate synthase 2)(Hyaluronic acid synthase 2)(HA  [...] 	COG1215	KOG2571	_	PF13641.3|Glyco_tranf_2_3|Glycosyltransferase like family 2|ENSGALT00000074165|m.2471:85-355;PF03142.12|Chitin_synth_2|Chitin synthase|ENSGALT00000074165|m.2471:206-358
ENSGALG00000029621	7.170294811	16.28698639	-1.182490223	3.28E-29	4.91E-28	down	yes	7.344725161	6.999577564	7.166581708	18.29061339	13.96380255	16.60654322	12	3580056	3597490	+	SEMA3F	protein_coding	GO:0001755|neural crest cell migration; GO:0007411|axon guidance; GO:0021612|facial nerve structural organization; GO:0021637|trigeminal nerve structural organization; GO:0021675|nerve development; GO:0021785|branchiomotor neuron axon guidance; GO:0036486|ventral trunk neural crest cell migration; GO:0048843|negative regulation of axon extension involved in axon guidance; GO:0048846|axon extension involved in axon guidance; GO:0050919|negative chemotaxis; GO:0061549|sympathetic ganglion development; GO:0097490|sympathetic neuron projection extension; GO:0097491|sympathetic neuron projection guidance; GO:1901166|neural crest cell migration involved in autonomic nervous system development; GO:1902285|semaphorin-plexin signaling pathway involved in neuron projection guidance; GO:1902287|semaphorin-plexin signaling pathway involved in axon guidance	GO:0005615|extracellular space	GO:0038191|neuropilin binding; GO:0045499|chemorepellent activity	ko:K06840|SEMA3	ko04360|Axon guidance	3265	XP_021265284.1	XP_021265284.1 semaphorin-3F isoform X2 [Numida meleagris]	sp|O88632|SEM3F_MOUSE	sp|O88632|SEM3F_MOUSE Semaphorin-3F OS=Mus musculus GN=Sema3f PE=2 SV=2	_	_	_	_	_	PF01403.16|Sema|Sema domain|ENSGALT00000072630|m.7376:60-495
ENSGALG00000029632	2.463525579	5.075509344	-1.039823457	1.97E-07	6.81E-07	down	yes	2.879475347	1.989898548	2.521202844	5.564941579	4.463658546	5.197927907	12	10860472	10880643	+	CHST13	protein_coding	GO:0002063|chondrocyte development; GO:0007585|respiratory gaseous exchange by respiratory system; GO:0009791|post-embryonic development; GO:0016051|carbohydrate biosynthetic process; GO:0030206|chondroitin sulfate biosynthetic process; GO:0030512|negative regulation of transforming growth factor beta receptor signaling pathway; GO:0033037|polysaccharide localization; GO:0036342|post-anal tail morphogenesis; GO:0042127|regulation of cell population proliferation; GO:0042733|embryonic digit morphogenesis; GO:0043066|negative regulation of apoptotic process; GO:0048589|developmental growth; GO:0048703|embryonic viscerocranium morphogenesis	GO:0000139|Golgi membrane; GO:0016020|membrane; GO:0016021|integral component of membrane	GO:0001537|N-acetylgalactosamine 4-O-sulfotransferase activity; GO:0047756|chondroitin 4-sulfotransferase activity; GO:0050659|N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity	ko:K07779|CHST13	ko00532|Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	1448	XP_001233230.2	XP_001233230.2 carbohydrate sulfotransferase 13 isoform X2 [Gallus gallus]	sp|Q9NPF2|CHSTB_HUMAN	sp|Q9NPF2|CHSTB_HUMAN Carbohydrate sulfotransferase 11 OS=Homo sapiens GN=CHST11 PE=1 SV=1	_	_	_	_	_	PF03567.11|Sulfotransfer_2|Sulfotransferase family|ENSGALT00000091490|m.7719:74-310
ENSGALG00000029766	38.04860873	18.1030663	1.071192028	7.49E-31	1.23E-29	up	yes	43.37824545	32.87026679	37.89731396	18.36446024	17.16286083	18.78187782	7	27871850	27912771	-	ITGB5	protein_coding	"GO:0002479|antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0006936|muscle contraction; GO:0007160|cell-matrix adhesion; GO:0007179|transforming growth factor beta receptor signaling pathway; GO:0007229|integrin-mediated signaling pathway; GO:0030198|extracellular matrix organization; GO:0035987|endodermal cell differentiation; GO:0043149|stress fiber assembly; GO:0090136|epithelial cell-cell adhesion"	GO:0005886|plasma membrane; GO:0005925|focal adhesion; GO:0009986|cell surface; GO:0034684|integrin alphav-beta5 complex; GO:0043235|receptor complex; GO:0045335|phagocytic vesicle; GO:0070062|extracellular exosome	GO:0001618|virus receptor activity; GO:0038023|signaling receptor activity	ko:K06588|ITGB5	ko04145|Phagosome; ko04151|PI3K-Akt signaling pathway; ko04510|Focal adhesion; ko04512|ECM-receptor interaction; ko04810|Regulation of actin cytoskeleton; ko05205|Proteoglycans in cancer; ko05410|Hypertrophic cardiomyopathy (HCM); ko05412|Arrhythmogenic right ventricular cardiomyopathy (ARVC); ko05414|Dilated cardiomyopathy	3010	NP_989814.1	NP_989814.1 integrin beta-5 precursor [Gallus gallus]	sp|P18084|ITB5_HUMAN	sp|P18084|ITB5_HUMAN Integrin beta-5 OS=Homo sapiens GN=ITGB5 PE=1 SV=1	9031.ENSGALP00000019200	"integrin, beta 5 "	_	KOG1226	_	"PF00362.15|Integrin_beta|Integrin, beta chain|ENSGALT00000081641|m.6585:73-501;PF07965.9|Integrin_B_tail|Integrin beta tail domain|ENSGALT00000081641|m.6585:673-755;PF08725.8|Integrin_b_cyt|Integrin beta cytoplasmic domain|ENSGALT00000081641|m.6585:780-824"
ENSGALG00000029819	2.275706052	13.95712473	-2.611323273	4.31E-60	2.14E-58	down	yes	2.564857247	1.798792276	2.463468632	14.11495199	15.68999285	12.06642936	9	8387258	8389147	-	SCG2	protein_coding	--	GO:0005576|extracellular region; GO:0030141|secretory granule	--	--	--	1890	XP_015132515.1	XP_015132515.1 secretogranin-2 [Gallus gallus]	sp|Q5FZP5|SCG2_PIG	sp|Q5FZP5|SCG2_PIG Secretogranin-2 OS=Sus scrofa GN=SCG2 PE=2 SV=1	9031.ENSGALP00000040027	secretogranin II (chromogranin C)	_	_	NOG47177	PF01271.14|Granin|Granin (chromogranin or secretogranin)|ENSGALT00000064960|m.8675:31-626
ENSGALG00000029836	2.503604413	5.465613937	-1.123263113	1.12E-12	6.25E-12	down	yes	2.506257919	2.61054521	2.394010111	5.132610489	6.356368286	4.907863036	2	57826956	57848803	+	GPLD1	protein_coding	GO:0001503|ossification; GO:0002042|cell migration involved in sprouting angiogenesis; GO:0002062|chondrocyte differentiation; GO:0002430|complement receptor mediated signaling pathway; GO:0006501|C-terminal protein lipidation; GO:0006507|GPI anchor release; GO:0008285|negative regulation of cell population proliferation; GO:0008286|insulin receptor signaling pathway; GO:0009749|response to glucose; GO:0010595|positive regulation of endothelial cell migration; GO:0010694|positive regulation of alkaline phosphatase activity; GO:0010867|positive regulation of triglyceride biosynthetic process; GO:0010897|negative regulation of triglyceride catabolic process; GO:0010907|positive regulation of glucose metabolic process; GO:0010983|positive regulation of high-density lipoprotein particle clearance; GO:0032869|cellular response to insulin stimulus; GO:0035690|cellular response to drug; GO:0035701|hematopoietic stem cell migration; GO:0035774|positive regulation of insulin secretion involved in cellular response to glucose stimulus; GO:0043065|positive regulation of apoptotic process; GO:0045919|positive regulation of cytolysis; GO:0046470|phosphatidylcholine metabolic process; GO:0051044|positive regulation of membrane protein ectodomain proteolysis; GO:0051047|positive regulation of secretion; GO:0070633|transepithelial transport; GO:0071277|cellular response to calcium ion; GO:0071397|cellular response to cholesterol; GO:0071401|cellular response to triglyceride; GO:0071467|cellular response to pH; GO:0097241|hematopoietic stem cell migration to bone marrow; GO:1900076|regulation of cellular response to insulin stimulus	GO:0005576|extracellular region; GO:0005615|extracellular space; GO:0005622|intracellular; GO:0005737|cytoplasm; GO:0005765|lysosomal membrane; GO:0031012|extracellular matrix; GO:0043231|intracellular membrane-bounded organelle; GO:0070062|extracellular exosome	GO:0004621|glycosylphosphatidylinositol phospholipase D activity; GO:0004630|phospholipase D activity; GO:0017080|sodium channel regulator activity	ko:K01127|E3.1.4.50	ko00563|Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	2571	XP_418910.4	XP_418910.4 phosphatidylinositol-glycan-specific phospholipase D [Gallus gallus]	sp|P80108|PHLD_HUMAN	sp|P80108|PHLD_HUMAN Phosphatidylinositol-glycan-specific phospholipase D OS=Homo sapiens GN=GPLD1 PE=1 SV=3	9031.ENSGALP00000020646	glycosylphosphatidylinositol specific phospholipase D1	_	KOG3637	_	"PF00882.15|Zn_dep_PLPC|Zinc dependent phospholipase C|ENSGALT00000091617|m.842:28-204;PF01839.20|FG-GAP|FG-GAP repeat|ENSGALT00000091617|m.842:382-419;PF01839.20|FG-GAP|FG-GAP repeat|ENSGALT00000091617|m.842:450-488;PF01839.20|FG-GAP|FG-GAP repeat|ENSGALT00000091617|m.842:514-547;PF13517.3|VCBS|Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella|ENSGALT00000091617|m.842:458-532"
ENSGALG00000029862	8.073061764	30.11845161	-1.898152754	5.59E-78	4.36E-76	down	yes	7.344818481	8.944160107	7.930206704	30.69043966	29.08637797	30.57853721	3	27397532	27407370	-	ENSGALG00000029862	protein_coding	GO:0016042|lipid catabolic process	GO:0016021|integral component of membrane; GO:0016324|apical plasma membrane	"GO:0004622|lysophospholipase activity; GO:0004623|phospholipase A2 activity; GO:0102567|phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine); GO:0102568|phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)"	"ko:K14621|PLB1,PLB"	ko00564|Glycerophospholipid metabolism; ko00565|Ether lipid metabolism; ko00590|Arachidonic acid metabolism; ko00591|Linoleic acid metabolism; ko00592|alpha-Linolenic acid metabolism; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko04977|Vitamin digestion and absorption	1650	XP_021247623.1	"XP_021247623.1 phospholipase B1, membrane-associated [Numida meleagris]"	sp|Q06HQ7|PLB1_MONDO	"sp|Q06HQ7|PLB1_MONDO Phospholipase B1, membrane-associated OS=Monodelphis domestica GN=PLB1 PE=2 SV=1"	_	_	_	_	_	_
ENSGALG00000029935	21.67606401	61.10889736	-1.494850286	3.21E-51	1.20E-49	down	yes	23.25011504	22.46035312	19.31772389	58.25150919	67.59569127	57.47949162	2	84402769	84415948	-	ENSGALG00000029935	protein_coding	GO:0010628|positive regulation of gene expression; GO:0031032|actomyosin structure organization; GO:0042060|wound healing; GO:0045785|positive regulation of cell adhesion; GO:0051549|positive regulation of keratinocyte migration	GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005856|cytoskeleton; GO:0005886|plasma membrane; GO:0005923|bicellular tight junction; GO:0045177|apical part of cell	GO:0005200|structural constituent of cytoskeleton; GO:0008092|cytoskeletal protein binding	"ko:K21111|EPB41L4B,EHM2,LULU2"	ko04530|Tight junction	1149	XP_015137834.1	XP_015137834.1 band 4.1-like protein 4B isoform X4 [Gallus gallus]	sp|Q9JMC8|E41LB_MOUSE	sp|Q9JMC8|E41LB_MOUSE Band 4.1-like protein 4B OS=Mus musculus GN=Epb41l4b PE=1 SV=2	_	_	_	_	_	PF09380.7|FERM_C|FERM C-terminal PH-like domain|ENSGALT00000074495|m.1260:84-172;PF08736.8|FA|FERM adjacent (FA)|ENSGALT00000074495|m.1260:181-221;PF00373.15|FERM_M|FERM central domain|ENSGALT00000074495|m.1260:2-78
ENSGALG00000029968	33.2500986	113.3224497	-1.768696647	5.01E-109	7.66E-107	down	yes	35.4206641	32.7557525	31.5738792	124.5929626	106.8504966	108.52389	28	3398994	3401884	-	GADD45B	protein_coding	GO:0000185|activation of MAPKKK activity; GO:0000186|activation of MAPKK activity; GO:0006469|negative regulation of protein kinase activity; GO:0006915|apoptotic process; GO:0006950|response to stress; GO:0007275|multicellular organism development; GO:0030154|cell differentiation; GO:0043065|positive regulation of apoptotic process; GO:0046330|positive regulation of JNK cascade; GO:0051726|regulation of cell cycle; GO:1900745|positive regulation of p38MAPK cascade	GO:0005634|nucleus; GO:0005737|cytoplasm	--	ko:K04402|GADD45	ko04010|MAPK signaling pathway; ko04068|FoxO signaling pathway; ko04110|Cell cycle; ko04115|p53 signaling pathway; ko04210|Apoptosis	1617	XP_015155443.1	XP_015155443.1 growth arrest and DNA damage-inducible protein GADD45 beta [Gallus gallus]	sp|O75293|GA45B_HUMAN	sp|O75293|GA45B_HUMAN Growth arrest and DNA damage-inducible protein GADD45 beta OS=Homo sapiens GN=GADD45B PE=1 SV=1	9615.ENSCAFP00000028654	"growth arrest and DNA-damage-inducible, beta"	_	_	NOG86411	PF01248.23|Ribosomal_L7Ae|Ribosomal protein L7Ae/L30e/S12e/Gadd45 family|ENSGALT00000065904|m.10176:34-119
ENSGALG00000030007	11.39803506	5.241710522	1.11919102	1.26E-40	3.29E-39	up	yes	11.98105136	11.12497479	11.08807904	5.050970925	5.272906673	5.40125397	26	2670099	2686743	+	ENSGALG00000030007	protein_coding	"GO:0006958|complement activation, classical pathway; GO:0030449|regulation of complement activation; GO:0043312|neutrophil degranulation; GO:0045087|innate immune response; GO:0045589|regulation of regulatory T cell differentiation; GO:0045957|negative regulation of complement activation, alternative pathway; GO:0045959|negative regulation of complement activation, classical pathway; GO:1900004|negative regulation of serine-type endopeptidase activity; GO:1900005|positive regulation of serine-type endopeptidase activity"	GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0009986|cell surface; GO:0030667|secretory granule membrane; GO:0070062|extracellular exosome; GO:0101003|ficolin-1-rich granule membrane	GO:0001618|virus receptor activity; GO:0001851|complement component C3b binding; GO:0001855|complement component C4b binding; GO:0001861|complement component C4b receptor activity; GO:0004877|complement component C3b receptor activity	"ko:K04011|CR1,CD35"	ko04610|Complement and coagulation cascades; ko04640|Hematopoietic cell lineage; ko05134|Legionellosis; ko05140|Leishmaniasis; ko05144|Malaria; ko05152|Tuberculosis	4040	XP_019478767.1	XP_019478767.1 PREDICTED: complement receptor type 1 [Meleagris gallopavo]	sp|P17927|CR1_HUMAN	sp|P17927|CR1_HUMAN Complement receptor type 1 OS=Homo sapiens GN=CR1 PE=1 SV=3	_	_	_	_	_	PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000106363|m.8043:3-58;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000106363|m.8043:63-120;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000106363|m.8043:128-185;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000106363|m.8043:190-250;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000106363|m.8043:255-311;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000106363|m.8043:316-372;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000106363|m.8043:377-432;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000106363|m.8043:438-493;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000106363|m.8043:497-557;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000106363|m.8043:562-621;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000106363|m.8043:626-686;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000106363|m.8043:691-746;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000106363|m.8043:751-807;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000106363|m.8043:811-865;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000106363|m.8043:876-933;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000106363|m.8043:938-992;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000106363|m.8043:998-1053;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000106363|m.8043:1117-1173;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000106363|m.8043:1178-1233;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000106363|m.8043:1249-1292
ENSGALG00000030031	4.475016217	12.08672317	-1.431431188	2.52E-12	1.36E-11	down	yes	3.158938196	5.790340572	4.475769883	12.33381576	12.59343299	11.33292075	2	113806150	113819007	-	TTPA	protein_coding	GO:0001892|embryonic placenta development; GO:0006629|lipid metabolic process; GO:0006810|transport; GO:0007584|response to nutrient; GO:0009268|response to pH; GO:0009636|response to toxic substance; GO:0042360|vitamin E metabolic process; GO:0051180|vitamin transport; GO:0051452|intracellular pH reduction; GO:0060548|negative regulation of cell death; GO:0090212|negative regulation of establishment of blood-brain barrier; GO:0120009|intermembrane lipid transfer	GO:0005770|late endosome; GO:0005829|cytosol	"GO:0005546|phosphatidylinositol-4,5-bisphosphate binding; GO:0008431|vitamin E binding; GO:0043325|phosphatidylinositol-3,4-bisphosphate binding; GO:0120013|lipid transfer activity"	--	--	834	XP_001234376.2	XP_001234376.2 alpha-tocopherol transfer protein [Gallus gallus]	sp|P49638|TTPA_HUMAN	sp|P49638|TTPA_HUMAN Alpha-tocopherol transfer protein OS=Homo sapiens GN=TTPA PE=1 SV=1	9031.ENSGALP00000024953	hypothetical protein LOC771997	_	KOG1471	_	"PF00650.17|CRAL_TRIO|CRAL/TRIO domain|ENSGALT00000068645|m.1849:94-246;PF03765.12|CRAL_TRIO_N|CRAL/TRIO, N-terminal domain|ENSGALT00000068645|m.1849:45-69"
ENSGALG00000030034	2.009494295	5.471075411	-1.440464913	1.11E-07	3.95E-07	down	yes	1.144376817	2.079404798	2.804701271	5.932796498	5.332771563	5.147658171	27	7903742	7906398	+	G6PC	protein_coding	GO:0005977|glycogen metabolic process; GO:0005980|glycogen catabolic process; GO:0006094|gluconeogenesis; GO:0006641|triglyceride metabolic process; GO:0008202|steroid metabolic process; GO:0010468|regulation of gene expression; GO:0015760|glucose-6-phosphate transport; GO:0032094|response to food; GO:0035264|multicellular organism growth; GO:0042593|glucose homeostasis; GO:0042632|cholesterol homeostasis; GO:0046415|urate metabolic process; GO:0046838|phosphorylated carbohydrate dephosphorylation; GO:0051156|glucose 6-phosphate metabolic process	GO:0005789|endoplasmic reticulum membrane; GO:0016021|integral component of membrane; GO:0030176|integral component of endoplasmic reticulum membrane	"GO:0004346|glucose-6-phosphatase activity; GO:0016773|phosphotransferase activity, alcohol group as acceptor; GO:0042301|phosphate ion binding"	ko:K01084|G6PC	ko00010|Glycolysis / Gluconeogenesis; ko00052|Galactose metabolism; ko00500|Starch and sucrose metabolism; ko01100|Metabolic pathways; ko04068|FoxO signaling pathway; ko04151|PI3K-Akt signaling pathway; ko04152|AMPK signaling pathway; ko04910|Insulin signaling pathway; ko04920|Adipocytokine signaling pathway; ko04922|Glucagon signaling pathway; ko04931|Insulin resistance; ko04973|Carbohydrate digestion and absorption	1059	XP_003642865.1	XP_003642865.1 glucose-6-phosphatase [Gallus gallus]	sp|P35575|G6PC_HUMAN	sp|P35575|G6PC_HUMAN Glucose-6-phosphatase OS=Homo sapiens GN=G6PC PE=1 SV=2	_	_	_	_	_	PF01569.18|PAP2|PAP2 superfamily|ENSGALT00000069866|m.9493:56-187
ENSGALG00000030064	1.792240288	4.617205241	-1.360349717	1.40E-11	7.13E-11	down	yes	1.844463412	1.917528458	1.614728994	4.8254757	3.821596519	5.204543503	4	2904832	2916879	+	ENSGALG00000030064	protein_coding	--	--	--	--	--	1914	XP_015133919.1	XP_015133919.1 UAP56-interacting factor isoform X2 [Gallus gallus]	_	_	9031.ENSGALP00000009474	similar to putative 40-2-3 protein	_	_	NOG246503	PF07078.8|FYTT|Forty-two-three protein|ENSGALT00000073845|m.16217:20-303
ENSGALG00000030075	0.263537126	0.080052339	1.602901002	4.95E-06	1.45E-05	up	yes	0.347155138	0.237277876	0.206178366	0.059757762	0.088429599	0.091969656	KZ626838.1	155851	191216	+	ENSGALG00000030075	protein_coding	--	GO:0070062|extracellular exosome	--	--	--	8955	XP_025002166.1	XP_025002166.1 IgGFc-binding protein-like [Gallus gallus]	sp|Q9Y6R7|FCGBP_HUMAN	sp|Q9Y6R7|FCGBP_HUMAN IgGFc-binding protein OS=Homo sapiens GN=FCGBP PE=1 SV=3	28377.ENSACAP00000016021	annotation not avaliable	_	KOG1216	_	PF00094.22|VWD|von Willebrand factor type D domain|ENSGALT00000049432|m.9897:458-614;PF00094.22|VWD|von Willebrand factor type D domain|ENSGALT00000049432|m.9897:849-1003;PF00094.22|VWD|von Willebrand factor type D domain|ENSGALT00000049432|m.9897:1230-1385;PF00094.22|VWD|von Willebrand factor type D domain|ENSGALT00000049432|m.9897:1643-1794;PF00094.22|VWD|von Willebrand factor type D domain|ENSGALT00000049432|m.9897:2035-2189;PF00094.22|VWD|von Willebrand factor type D domain|ENSGALT00000049432|m.9897:2427-2578;PF08742.8|C8|C8 domain|ENSGALT00000049432|m.9897:659-727;PF08742.8|C8|C8 domain|ENSGALT00000049432|m.9897:1045-1112;PF08742.8|C8|C8 domain|ENSGALT00000049432|m.9897:1430-1498;PF08742.8|C8|C8 domain|ENSGALT00000049432|m.9897:1845-1914;PF08742.8|C8|C8 domain|ENSGALT00000049432|m.9897:2234-2302;PF08742.8|C8|C8 domain|ENSGALT00000049432|m.9897:2608-2642;PF01826.14|TIL|Trypsin Inhibitor like cysteine rich domain|ENSGALT00000049432|m.9897:731-785;PF01826.14|TIL|Trypsin Inhibitor like cysteine rich domain|ENSGALT00000049432|m.9897:1116-1169;PF01826.14|TIL|Trypsin Inhibitor like cysteine rich domain|ENSGALT00000049432|m.9897:1502-1555;PF01826.14|TIL|Trypsin Inhibitor like cysteine rich domain|ENSGALT00000049432|m.9897:1918-1971;PF01826.14|TIL|Trypsin Inhibitor like cysteine rich domain|ENSGALT00000049432|m.9897:2306-2361;PF12714.4|TILa|TILa domain|ENSGALT00000049432|m.9897:787-841;PF12714.4|TILa|TILa domain|ENSGALT00000049432|m.9897:1556-1609;PF12714.4|TILa|TILa domain|ENSGALT00000049432|m.9897:2362-2416
ENSGALG00000030121	0.074571631	1.937534801	-4.525331502	1.58E-14	1.01E-13	down	yes	0	0.024025592	0.1996893	2.2186184	1.59403817	1.999947834	15	8330780	8338969	+	ENSGALG00000030121	protein_coding	GO:0008645|hexose transmembrane transport	GO:0005634|nucleus; GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0030054|cell junction	GO:0051119|sugar transmembrane transporter activity	--	--	1608	XP_001232846.2	"XP_001232846.2 solute carrier family 2, facilitated glucose transporter member 11 [Gallus gallus]"	sp|Q9BYW1|GTR11_HUMAN	"sp|Q9BYW1|GTR11_HUMAN Solute carrier family 2, facilitated glucose transporter member 11 OS=Homo sapiens GN=SLC2A11 PE=2 SV=1"	59729.ENSTGUP00000010575	annotation not avaliable	COG0477	KOG0569	_	PF00083.21|Sugar_tr|Sugar (and other) transporter|ENSGALT00000056617|m.10797:20-472;PF07690.13|MFS_1|Major Facilitator Superfamily|ENSGALT00000056617|m.10797:68-297;PF07690.13|MFS_1|Major Facilitator Superfamily|ENSGALT00000056617|m.10797:285-473
ENSGALG00000030157	6.220152519	15.7187895	-1.336068257	3.07E-33	5.75E-32	down	yes	5.434591274	6.880065309	6.345800973	14.09727973	16.82302612	16.23606264	10	15422025	15517080	+	MCTP2	protein_coding	GO:0007275|multicellular organism development; GO:0019722|calcium-mediated signaling	GO:0005654|nucleoplasm; GO:0005783|endoplasmic reticulum; GO:0005829|cytosol; GO:0016020|membrane; GO:0016021|integral component of membrane	GO:0005509|calcium ion binding	--	--	2802	XP_004943920.2	XP_004943920.2 multiple C2 and transmembrane domain-containing protein 2 isoform X1 [Gallus gallus]	sp|Q6DN12|MCTP2_HUMAN	sp|Q6DN12|MCTP2_HUMAN Multiple C2 and transmembrane domain-containing protein 2 OS=Homo sapiens GN=MCTP2 PE=1 SV=3	_	_	_	_	_	PF00168.27|C2|C2 domain|ENSGALT00000067125|m.5705:213-308;PF00168.27|C2|C2 domain|ENSGALT00000067125|m.5705:373-464;PF00168.27|C2|C2 domain|ENSGALT00000067125|m.5705:528-619;PF08372.7|PRT_C|Plant phosphoribosyltransferase C-terminal|ENSGALT00000067125|m.5705:752-870
ENSGALG00000030160	0.430293948	2.438715378	-2.475486175	6.86E-18	5.59E-17	down	yes	0.545707482	0.237104118	0.508070244	2.600047156	2.038350193	2.677748785	11	510445	522708	-	DRC7	protein_coding	--	GO:0005737|cytoplasm; GO:0005856|cytoskeleton; GO:0031514|motile cilium	--	--	--	2607	XP_004944089.1	XP_004944089.1 dynein regulatory complex subunit 7 [Gallus gallus]	sp|G2HE57|DRC7_PANTR	sp|G2HE57|DRC7_PANTR Dynein regulatory complex subunit 7 OS=Pan troglodytes GN=DRC7 PE=2 SV=1	_	_	_	_	_	_
ENSGALG00000030176	1.885183105	0.747262407	1.323472028	0.000339124	0.00076778	up	yes	2.53023764	1.366969163	1.758342512	0.684588008	0.91291906	0.644280152	17	2777985	2779542	+	SLC31A2	protein_coding	GO:0006811|ion transport; GO:0006878|cellular copper ion homeostasis; GO:1902311|regulation of copper ion transmembrane transport	GO:0005770|late endosome; GO:0016020|membrane; GO:0016021|integral component of membrane; GO:0055037|recycling endosome	--	"ko:K14687|SLC31A2,CTR2"	--	1187	NP_001264614.1	NP_001264614.1 probable low affinity copper uptake protein 2 [Gallus gallus]	sp|Q9CPU9|COPT2_MOUSE	sp|Q9CPU9|COPT2_MOUSE Probable low affinity copper uptake protein 2 OS=Mus musculus GN=Slc31a2 PE=1 SV=1	9031.ENSGALP00000019683	"solute carrier family 31 (copper transporters), member 2"	_	KOG3386	_	PF04145.12|Ctr|Ctr copper transporter family|ENSGALT00000049510|m.11831:80-221
ENSGALG00000030185	21.8103998	9.127319242	1.255834669	1.03E-74	7.30E-73	up	yes	21.07015542	22.3786794	21.98236459	9.000345155	8.900305181	9.481307389	2	126738656	126768617	+	PTDSS1	protein_coding	GO:0006659|phosphatidylserine biosynthetic process	GO:0005789|endoplasmic reticulum membrane; GO:0016021|integral component of membrane	GO:0016740|transferase activity	ko:K08729|PTDSS1	ko00564|Glycerophospholipid metabolism; ko01100|Metabolic pathways	5034	XP_015711395.1	XP_015711395.1 PREDICTED: phosphatidylserine synthase 1 isoform X2 [Coturnix japonica]	sp|Q5ZM65|PTSS1_CHICK	sp|Q5ZM65|PTSS1_CHICK Phosphatidylserine synthase 1 OS=Gallus gallus GN=PTDSS1 PE=2 SV=2	9031.ENSGALP00000025730	phosphatidylserine synthase 1 	_	KOG2735	_	PF03034.12|PSS|Phosphatidyl serine synthase|ENSGALT00000059601|m.2165:96-372
ENSGALG00000030220	11.57664898	3.889120782	1.571242628	1.21E-53	5.00E-52	up	yes	12.12265678	10.93775648	11.66953367	3.642123499	3.83557316	4.189665688	11	1000784	1009243	+	ELMO3	protein_coding	GO:0006909|phagocytosis; GO:0006915|apoptotic process; GO:0016477|cell migration	GO:0005737|cytoplasm	GO:0017124|SH3 domain binding	ko:K19241|ELMO3	ko05100|Bacterial invasion of epithelial cells; ko05131|Shigellosis	3412	NP_001243730.1	NP_001243730.1 engulfment and cell motility protein 3 [Gallus gallus]	sp|Q96BJ8|ELMO3_HUMAN	sp|Q96BJ8|ELMO3_HUMAN Engulfment and cell motility protein 3 OS=Homo sapiens GN=ELMO3 PE=1 SV=3	59729.ENSTGUP00000005650	Engulfment and cell motility protein 3 [Taeniopygia guttata]	_	KOG2999	_	PF11841.5|DUF3361|Domain of unknown function (DUF3361)|ENSGALT00000064299|m.6222:132-285;PF04727.10|ELMO_CED12|ELMO/CED-12 family|ENSGALT00000064299|m.6222:311-486;PF16457.2|PH_12|Pleckstrin homology domain|ENSGALT00000064299|m.6222:553-679
ENSGALG00000030229	0.102771353	0.434515298	-1.978832444	1.46E-11	7.42E-11	down	yes	0.067614596	0.148725243	0.091974219	0.38331327	0.456512633	0.463719992	23	4766719	4994805	+	CSMD2	protein_coding	--	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	--	ko:K17495|CSMD	--	10910	XP_015153311.1	XP_015153311.1 CUB and sushi domain-containing protein 2 [Gallus gallus]	sp|Q7Z408|CSMD2_HUMAN	sp|Q7Z408|CSMD2_HUMAN CUB and sushi domain-containing protein 2 OS=Homo sapiens GN=CSMD2 PE=1 SV=2	9031.ENSGALP00000032534	CUB and Sushi multiple domains 2	_	KOG4297	_	PF00431.17|CUB|CUB domain|ENSGALT00000071991|m.5651:89-194;PF00431.17|CUB|CUB domain|ENSGALT00000071991|m.5651:265-366;PF00431.17|CUB|CUB domain|ENSGALT00000071991|m.5651:468-576;PF00431.17|CUB|CUB domain|ENSGALT00000071991|m.5651:641-746;PF00431.17|CUB|CUB domain|ENSGALT00000071991|m.5651:815-920;PF00431.17|CUB|CUB domain|ENSGALT00000071991|m.5651:987-1094;PF00431.17|CUB|CUB domain|ENSGALT00000071991|m.5651:1161-1266;PF00431.17|CUB|CUB domain|ENSGALT00000071991|m.5651:1334-1440;PF00431.17|CUB|CUB domain|ENSGALT00000071991|m.5651:1508-1613;PF00431.17|CUB|CUB domain|ENSGALT00000071991|m.5651:1682-1787;PF00431.17|CUB|CUB domain|ENSGALT00000071991|m.5651:1859-1964;PF00431.17|CUB|CUB domain|ENSGALT00000071991|m.5651:2031-2136;PF00431.17|CUB|CUB domain|ENSGALT00000071991|m.5651:2203-2298;PF00431.17|CUB|CUB domain|ENSGALT00000071991|m.5651:2382-2484;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000071991|m.5651:202-259;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000071991|m.5651:406-463;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000071991|m.5651:584-637;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000071991|m.5651:754-811;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000071991|m.5651:930-983;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000071991|m.5651:1102-1157;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000071991|m.5651:1274-1330;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000071991|m.5651:1448-1504;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000071991|m.5651:1621-1678;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000071991|m.5651:1798-1855;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000071991|m.5651:1972-2027;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000071991|m.5651:2144-2199;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000071991|m.5651:2315-2372;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000071991|m.5651:2489-2547;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000071991|m.5651:2552-2609;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000071991|m.5651:2614-2674;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000071991|m.5651:2679-2732;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000071991|m.5651:2737-2790;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000071991|m.5651:2795-2848;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000071991|m.5651:2853-2911;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000071991|m.5651:2916-2969;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000071991|m.5651:2977-3030;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000071991|m.5651:3035-3089;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000071991|m.5651:3094-3149;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000071991|m.5651:3154-3207;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000071991|m.5651:3212-3265;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000071991|m.5651:3273-3327;PF00084.17|Sushi|Sushi repeat (SCR repeat)|ENSGALT00000071991|m.5651:3332-3387
ENSGALG00000030245	4.056518377	8.828499705	-1.120007366	6.46E-14	3.97E-13	down	yes	3.901973137	4.238414953	4.029167041	9.741312837	7.590337035	9.153849243	5	54739247	54749789	+	ENSGALG00000030245	protein_coding	--	--	--	--	--	1823	XP_004936596.1	"XP_004936596.1 inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 [Gallus gallus]"	_	_	_	_	_	_	_	PF03281.11|Mab-21|Mab-21 protein|ENSGALT00000070762|m.4027:373-481
ENSGALG00000030247	0.473652744	0.078091452	2.456897652	3.59E-07	1.20E-06	up	yes	0.313146917	0.567956884	0.539854432	0.07439346	0.110811781	0.049069114	25	253773	258260	-	TMOD4	protein_coding	GO:0006936|muscle contraction; GO:0007015|actin filament organization; GO:0030239|myofibril assembly; GO:0051694|pointed-end actin filament capping	GO:0005865|striated muscle thin filament	GO:0005523|tropomyosin binding; GO:0051015|actin filament binding	ko:K10370|TMOD	--	2647	XP_010722287.1	XP_010722287.1 PREDICTED: tropomodulin-4 isoform X1 [Meleagris gallopavo]	sp|Q0VC48|TMOD4_BOVIN	sp|Q0VC48|TMOD4_BOVIN Tropomodulin-4 OS=Bos taurus GN=TMOD4 PE=2 SV=1	_	_	_	_	_	PF03250.11|Tropomodulin|Tropomodulin|ENSGALT00000105067|m.6585:37-127;PF03250.11|Tropomodulin|Tropomodulin|ENSGALT00000105067|m.6585:228-280;PF08265.8|YL1_C|YL1 nuclear protein C-terminal domain|ENSGALT00000105067|m.6588:52-80
ENSGALG00000030253	38.37541259	14.97842492	1.356709372	1.51E-59	7.34E-58	up	yes	38.18935342	38.09115635	38.845728	13.10542664	16.97828282	14.8515653	20	1079716	1091358	+	RBM12	protein_coding	--	GO:0005654|nucleoplasm	GO:0003723|RNA binding	--	--	4847	NP_996869.2	NP_996869.2 RNA-binding protein 12 [Gallus gallus]	sp|Q8R4X3|RBM12_MOUSE	sp|Q8R4X3|RBM12_MOUSE RNA-binding protein 12 OS=Mus musculus GN=Rbm12 PE=1 SV=3	_	_	_	_	_	"PF00076.19|RRM_1|RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)|ENSGALT00000058537|m.2820:433-501;PF00076.19|RRM_1|RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)|ENSGALT00000058537|m.2820:549-615;PF00076.19|RRM_1|RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)|ENSGALT00000058537|m.2820:807-876"
ENSGALG00000030356	1.257527481	0.29450488	2.057479773	3.53E-07	1.18E-06	up	yes	1.727576692	0.992217573	1.052788178	0.389894906	0.193587576	0.300032158	4	78500599	78512725	-	OTOP1	protein_coding	GO:0031214|biomineral tissue development	GO:0005615|extracellular space; GO:0016021|integral component of membrane	--	--	--	1830	XP_025005572.1	XP_025005572.1 proton channel OTOP1 [Gallus gallus]	sp|Q7RTM1|OTOP1_HUMAN	sp|Q7RTM1|OTOP1_HUMAN Otopetrin-1 OS=Homo sapiens GN=OTOP1 PE=2 SV=1	9031.ENSGALP00000024129	otopetrin 1	_	KOG4740	_	PF03189.10|Otopetrin|Otopetrin|ENSGALT00000049501|m.1374:132-455;PF03189.10|Otopetrin|Otopetrin|ENSGALT00000049501|m.1374:530-595
ENSGALG00000030376	2.814833062	13.51616377	-2.25951521	2.88E-113	5.04E-111	down	yes	2.494564147	3.071513107	2.878421931	13.42954034	14.41172173	12.70722923	21	5314485	5343907	+	DHRS3	protein_coding	GO:0001523|retinoid metabolic process; GO:0003151|outflow tract morphogenesis; GO:0030278|regulation of ossification; GO:0048387|negative regulation of retinoic acid receptor signaling pathway; GO:0060021|roof of mouth development; GO:0060349|bone morphogenesis; GO:0060411|cardiac septum morphogenesis	GO:0016021|integral component of membrane	GO:0004745|retinol dehydrogenase activity; GO:0052650|NADP-retinol dehydrogenase activity	ko:K11146|DHRS3	ko00830|Retinol metabolism; ko01100|Metabolic pathways	4798	NP_001264839.1	NP_001264839.1 short-chain dehydrogenase/reductase 3 [Gallus gallus]	sp|O88876|DHRS3_MOUSE	sp|O88876|DHRS3_MOUSE Short-chain dehydrogenase/reductase 3 OS=Mus musculus GN=Dhrs3 PE=1 SV=2	9031.ENSGALP00000006759	similar to Dhrs3 protein	COG1028	KOG1201	_	PF00106.22|adh_short|short chain dehydrogenase|ENSGALT00000084796|m.4255:40-229;PF13561.3|adh_short_C2|Enoyl-(Acyl carrier protein) reductase|ENSGALT00000084796|m.4255:48-263;PF08659.7|KR|KR domain|ENSGALT00000084796|m.4255:41-199;PF02719.12|Polysacc_synt_2|Polysaccharide biosynthesis protein|ENSGALT00000084796|m.4255:41-110
ENSGALG00000030436	2686.804363	1029.050214	1.384569245	9.93E-07	3.18E-06	up	yes	3580.442069	2692.763735	1787.207286	1022.829857	1067.545451	996.7753346	MT	10776	11126	+	ND3	protein_coding	GO:0055114|oxidation-reduction process	GO:0005747|mitochondrial respiratory chain complex I; GO:0016021|integral component of membrane	GO:0008137|NADH dehydrogenase (ubiquinone) activity	ko:K03880|ND3	ko00190|Oxidative phosphorylation; ko01100|Metabolic pathways; ko04723|Retrograde endocannabinoid signaling; ko05012|Parkinson's disease	351	NP_006922.1	NP_006922.1 NADH dehydrogenase subunit 3 (mitochondrion) [Gallus gallus]	sp|P18938|NU3M_CHICK	sp|P18938|NU3M_CHICK NADH-ubiquinone oxidoreductase chain 3 OS=Gallus gallus GN=MT-ND3 PE=3 SV=1	9031.ENSGALP00000034619	NADH-ubiquinone oxidoreductase chain 3 (EC 1.6.5.3)(NADH dehydrogenase subunit 3); Core subu [...] 	_	_	NOG297103	_
ENSGALG00000030493	0.104671396	0.267382583	-1.274371631	0.014245979	0.024416193	down	yes	0.175261404	0.110144411	0.028608374	0.263697038	0.282212067	0.256238644	2	41127304	41147533	-	ENTPD3	protein_coding	GO:0009134|nucleoside diphosphate catabolic process; GO:0009143|nucleoside triphosphate catabolic process; GO:0034656|nucleobase-containing small molecule catabolic process	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0005524|ATP binding; GO:0017110|nucleoside-diphosphatase activity; GO:0017111|nucleoside-triphosphatase activity; GO:0102485|dATP phosphohydrolase activity; GO:0102486|dCTP phosphohydrolase activity; GO:0102487|dUTP phosphohydrolase activity; GO:0102488|dTTP phosphohydrolase activity; GO:0102489|GTP phosphohydrolase activity; GO:0102490|8-oxo-dGTP phosphohydrolase activity; GO:0102491|dGTP phosphohydrolase activity	"ko:K01510|ENTPD1_3_8,CD39"	ko00230|Purine metabolism; ko00240|Pyrimidine metabolism; ko05169|Epstein-Barr virus infection	4209	NP_001308493.1	NP_001308493.1 ectonucleoside triphosphate diphosphohydrolase 3 [Gallus gallus]	sp|O75355|ENTP3_HUMAN	sp|O75355|ENTP3_HUMAN Ectonucleoside triphosphate diphosphohydrolase 3 OS=Homo sapiens GN=ENTPD3 PE=1 SV=2	9031.ENSGALP00000018774	ectonucleoside triphosphate diphosphohydrolase 3	COG5371	KOG1386	_	PF01150.14|GDA1_CD39|GDA1/CD39 (nucleoside phosphatase) family|ENSGALT00000078128|m.467:39-460
ENSGALG00000030502	0.497273673	1.142013115	-1.183320948	0.001282867	0.00266201	down	yes	0.680763425	0.479170881	0.331886712	0.942329979	1.216962298	1.266747068	25	3958394	3965648	-	ADAMTS4	protein_coding	GO:0001501|skeletal system development; GO:0006508|proteolysis; GO:0022617|extracellular matrix disassembly	GO:0005576|extracellular region; GO:0005615|extracellular space; GO:0016607|nuclear speck; GO:0031012|extracellular matrix	GO:0002020|protease binding; GO:0004222|metalloendopeptidase activity; GO:0008233|peptidase activity; GO:0008237|metallopeptidase activity; GO:0008270|zinc ion binding	ko:K07764|ADAMTS4	--	1935	XP_015135540.2	XP_015135540.2 A disintegrin and metalloproteinase with thrombospondin motifs 4 [Gallus gallus]	sp|O75173|ATS4_HUMAN	sp|O75173|ATS4_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 4 OS=Homo sapiens GN=ADAMTS4 PE=1 SV=3	_	_	_	_	_	PF05986.11|ADAM_spacer1|ADAM-TS Spacer 1|ENSGALT00000077338|m.7393:502-620;PF01421.16|Reprolysin|Reprolysin (M12B) family zinc metalloprotease|ENSGALT00000077338|m.7393:106-254;PF13688.3|Reprolysin_5|Metallo-peptidase family M12|ENSGALT00000077338|m.7393:43-217;PF13582.3|Reprolysin_3|Metallo-peptidase family M12B Reprolysin-like|ENSGALT00000077338|m.7393:88-198;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000077338|m.7393:343-393
ENSGALG00000030516	5.088167822	0.801973626	2.650474092	3.78E-16	2.75E-15	up	yes	4.688613861	5.020127134	5.55576247	0.61586507	0.765278901	1.024776908	4	89848236	89855757	-	EMX1	protein_coding	"GO:0006355|regulation of transcription, DNA-templated; GO:0007275|multicellular organism development"	GO:0005634|nucleus	GO:0043565|sequence-specific DNA binding	ko:K09317|EMX	--	708	XP_001232151.3	XP_001232151.3 homeobox protein EMX1 [Gallus gallus]	sp|Q6GLB9|EMX1_XENTR	sp|Q6GLB9|EMX1_XENTR Homeobox protein EMX1 OS=Xenopus tropicalis GN=emx1 PE=2 SV=1	9031.ENSGALP00000025888	empty spiracles homeobox 1	_	KOG0843	_	PF00046.26|Homeobox|Homeobox domain|ENSGALT00000069688|m.1722:138-194
ENSGALG00000030526	0.144355395	0.360188355	-1.262003599	0.013895123	0.02387582	down	yes	0.146465849	0.161083331	0.125517006	0.330557182	0.470654501	0.279353381	1	135138720	135153025	+	ENSGALG00000030526	protein_coding	GO:0009314|response to radiation; GO:0010286|heat acclimation; GO:0019221|cytokine-mediated signaling pathway; GO:0030728|ovulation; GO:0050727|regulation of inflammatory response; GO:0070498|interleukin-1-mediated signaling pathway; GO:0070555|response to interleukin-1; GO:0070849|response to epidermal growth factor; GO:0071333|cellular response to glucose stimulus; GO:0071559|response to transforming growth factor beta; GO:0071731|response to nitric oxide; GO:1990834|response to odorant; GO:2000391|positive regulation of neutrophil extravasation; GO:2000661|positive regulation of interleukin-1-mediated signaling pathway; GO:2001224|positive regulation of neuron migration	GO:0005615|extracellular space; GO:0005634|nucleus; GO:0005886|plasma membrane; GO:0009986|cell surface; GO:0014069|postsynaptic density; GO:0016020|membrane; GO:0016021|integral component of membrane; GO:0030424|axon; GO:0032991|protein-containing complex	"GO:0002020|protease binding; GO:0004908|interleukin-1 receptor activity; GO:0004909|interleukin-1, type I, activating receptor activity; GO:0005161|platelet-derived growth factor receptor binding; GO:0019966|interleukin-1 binding; GO:0035255|ionotropic glutamate receptor binding"	"ko:K05172|IL1RL2,IL1RRP2"	--	2878	XP_416915.6	XP_416915.6 interleukin-1 receptor type 1 isoform X3 [Gallus gallus]	sp|Q02955|IL1R1_RAT	sp|Q02955|IL1R1_RAT Interleukin-1 receptor type 1 OS=Rattus norvegicus GN=Il1r1 PE=2 SV=1	_	_	_	_	_	PF01582.17|TIR|TIR domain|ENSGALT00000066391|m.3714:424-565;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000066391|m.3714:247-338;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000066391|m.3714:155-229
ENSGALG00000030542	2.216240878	4.895854197	-1.139894657	1.45E-13	8.62E-13	down	yes	1.716721544	2.157774389	2.774226701	5.004498163	5.247368414	4.435696013	10	10215219	10367585	+	SEMA6D	protein_coding	GO:0014911|positive regulation of smooth muscle cell migration; GO:0014912|negative regulation of smooth muscle cell migration; GO:0021591|ventricular system development; GO:0030154|cell differentiation	GO:0005794|Golgi apparatus; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane	GO:0030215|semaphorin receptor binding	ko:K06842|SEMA6	ko04360|Axon guidance	4027	XP_015147423.1	XP_015147423.1 semaphorin-6D isoform X1 [Gallus gallus]	sp|Q8NFY4|SEM6D_HUMAN	sp|Q8NFY4|SEM6D_HUMAN Semaphorin-6D OS=Homo sapiens GN=SEMA6D PE=1 SV=1	9031.ENSGALP00000007721	similar to KIAA1479 protein	_	KOG3611	_	PF01403.16|Sema|Sema domain|ENSGALT00000098604|m.5507:66-474;PF01437.22|PSI|Plexin repeat|ENSGALT00000098604|m.5507:514-543
ENSGALG00000030613	2.221854932	0.603257992	1.863677221	1.98E-14	1.26E-13	up	yes	2.681979706	1.990410702	1.99317439	0.738162298	0.420404611	0.651207068	13	13957973	13973578	+	PDGFRB	protein_coding	GO:0000165|MAPK cascade; GO:0006024|glycosaminoglycan biosynthetic process; GO:0007165|signal transduction; GO:0007568|aging; GO:0008284|positive regulation of cell population proliferation; GO:0008584|male gonad development; GO:0009636|response to toxic substance; GO:0010863|positive regulation of phospholipase C activity; GO:0014066|regulation of phosphatidylinositol 3-kinase signaling; GO:0014068|positive regulation of phosphatidylinositol 3-kinase signaling; GO:0014911|positive regulation of smooth muscle cell migration; GO:0016477|cell migration; GO:0018108|peptidyl-tyrosine phosphorylation; GO:0030335|positive regulation of cell migration; GO:0032355|response to estradiol; GO:0032516|positive regulation of phosphoprotein phosphatase activity; GO:0032526|response to retinoic acid; GO:0032956|regulation of actin cytoskeleton organization; GO:0032967|positive regulation of collagen biosynthetic process; GO:0034405|response to fluid shear stress; GO:0035025|positive regulation of Rho protein signal transduction; GO:0035441|cell migration involved in vasculogenesis; GO:0035789|metanephric mesenchymal cell migration; GO:0035791|platelet-derived growth factor receptor-beta signaling pathway; GO:0035793|positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway; GO:0035909|aorta morphogenesis; GO:0038091|positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway; GO:0038111|interleukin-7-mediated signaling pathway; GO:0042060|wound healing; GO:0042542|response to hydrogen peroxide; GO:0043065|positive regulation of apoptotic process; GO:0043066|negative regulation of apoptotic process; GO:0043406|positive regulation of MAP kinase activity; GO:0043552|positive regulation of phosphatidylinositol 3-kinase activity; GO:0043627|response to estrogen; GO:0045840|positive regulation of mitotic nuclear division; GO:0046488|phosphatidylinositol metabolic process; GO:0046777|protein autophosphorylation; GO:0048008|platelet-derived growth factor receptor signaling pathway; GO:0048015|phosphatidylinositol-mediated signaling; GO:0048146|positive regulation of fibroblast proliferation; GO:0048661|positive regulation of smooth muscle cell proliferation; GO:0048839|inner ear development; GO:0050921|positive regulation of chemotaxis; GO:0055003|cardiac myofibril assembly; GO:0055093|response to hyperoxia; GO:0060326|cell chemotaxis; GO:0060437|lung growth; GO:0060981|cell migration involved in coronary angiogenesis; GO:0061298|retina vasculature development in camera-type eye; GO:0070374|positive regulation of ERK1 and ERK2 cascade; GO:0071670|smooth muscle cell chemotaxis; GO:0072075|metanephric mesenchyme development; GO:0072262|metanephric glomerular mesangial cell proliferation involved in metanephros development; GO:0072277|metanephric glomerular capillary formation; GO:0072278|metanephric comma-shaped body morphogenesis; GO:0072284|metanephric S-shaped body morphogenesis; GO:0090280|positive regulation of calcium ion import; GO:2000379|positive regulation of reactive oxygen species metabolic process; GO:2000491|positive regulation of hepatic stellate cell activation; GO:2000573|positive regulation of DNA biosynthetic process; GO:2000587|negative regulation of platelet-derived growth factor receptor-beta signaling pathway	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005886|plasma membrane; GO:0005925|focal adhesion; GO:0009986|cell surface; GO:0016020|membrane; GO:0016021|integral component of membrane; GO:0016324|apical plasma membrane; GO:0031226|intrinsic component of plasma membrane; GO:0031410|cytoplasmic vesicle; GO:0043202|lysosomal lumen; GO:0070062|extracellular exosome	"GO:0004713|protein tyrosine kinase activity; GO:0004992|platelet activating factor receptor activity; GO:0005017|platelet-derived growth factor-activated receptor activity; GO:0005019|platelet-derived growth factor beta-receptor activity; GO:0005088|Ras guanyl-nucleotide exchange factor activity; GO:0005102|signaling receptor binding; GO:0005161|platelet-derived growth factor receptor binding; GO:0005524|ATP binding; GO:0019899|enzyme binding; GO:0019901|protein kinase binding; GO:0038085|vascular endothelial growth factor binding; GO:0043548|phosphatidylinositol 3-kinase binding; GO:0046934|phosphatidylinositol-4,5-bisphosphate 3-kinase activity; GO:0048407|platelet-derived growth factor binding"	"ko:K05089|PDGFRB,CD140B"	ko01521|EGFR tyrosine kinase inhibitor resistance; ko04010|MAPK signaling pathway; ko04014|Ras signaling pathway; ko04015|Rap1 signaling pathway; ko04020|Calcium signaling pathway; ko04060|Cytokine-cytokine receptor interaction; ko04072|Phospholipase D signaling pathway; ko04151|PI3K-Akt signaling pathway; ko04510|Focal adhesion; ko04540|Gap junction; ko04810|Regulation of actin cytoskeleton; ko05166|HTLV-I infection; ko05200|Pathways in cancer; ko05206|MicroRNAs in cancer; ko05214|Glioma; ko05215|Prostate cancer; ko05218|Melanoma; ko05230|Central carbon metabolism in cancer; ko05231|Choline metabolism in cancer	3222	XP_025010809.1	XP_025010809.1 platelet-derived growth factor receptor beta [Gallus gallus]	sp|P09619|PGFRB_HUMAN	sp|P09619|PGFRB_HUMAN Platelet-derived growth factor receptor beta OS=Homo sapiens GN=PDGFRB PE=1 SV=1	_	_	_	_	_	PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000067683|m.8896:588-935;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000067683|m.8896:590-685;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000067683|m.8896:777-934;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000067683|m.8896:217-294;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000067683|m.8896:219-304;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000067683|m.8896:318-413;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000067683|m.8896:221-300;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000067683|m.8896:218-310
ENSGALG00000030677	11.39024303	25.66817637	-1.171478168	3.69E-45	1.14E-43	down	yes	11.80586861	10.86477614	11.50008434	26.17295181	23.83484463	26.99673268	6	18374424	18392107	+	ABCG2	protein_coding	GO:0006810|transport; GO:0006879|cellular iron ion homeostasis; GO:0033344|cholesterol efflux; GO:0042493|response to drug; GO:0046415|urate metabolic process	GO:0005634|nucleus; GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0016324|apical plasma membrane; GO:0031966|mitochondrial membrane; GO:0043235|receptor complex	GO:0005215|transporter activity; GO:0005524|ATP binding; GO:0008559|ATPase-coupled xenobiotic transmembrane transporter activity; GO:0015232|heme transporter activity; GO:0042626|ATPase-coupled transmembrane transporter activity; GO:0042802|identical protein binding; GO:0042803|protein homodimerization activity	"ko:K05681|ABCG2,CD338"	ko01523|Antifolate resistance; ko02010|ABC transporters; ko04976|Bile secretion	2937	NP_001315419.1	NP_001315419.1 ATP-binding cassette sub-family G member 2 [Gallus gallus]	sp|Q9UNQ0|ABCG2_HUMAN	sp|Q9UNQ0|ABCG2_HUMAN ATP-binding cassette sub-family G member 2 OS=Homo sapiens GN=ABCG2 PE=1 SV=3	9031.ENSGALP00000039306	"ATP-binding cassette, sub-family G (WHITE), member 2"	COG0842;COG1131	KOG0061	_	PF01061.21|ABC2_membrane|ABC-2 type transporter|ENSGALT00000055859|m.4797:412-623;PF00005.24|ABC_tran|ABC transporter|ENSGALT00000055859|m.4797:103-240
ENSGALG00000030718	17.29349509	6.209919055	1.476095763	0.022743498	0.037356933	up	yes	17.7925095	17.31345022	16.77452554	3.511559989	12.20593312	2.912264052	4	13177222	13181501	-	ENSGALG00000030718	protein_coding	GO:0006488|dolichol-linked oligosaccharide biosynthetic process	GO:0043541|UDP-N-acetylglucosamine transferase complex	GO:0003723|RNA binding; GO:0004577|N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity	ko:K07432|ALG13	ko00510|N-Glycan biosynthesis; ko00513|Various types of N-glycan biosynthesis; ko01100|Metabolic pathways	1850	XP_015134150.1	XP_015134150.1 putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 [Gallus gallus]	sp|Q5I0K7|ALG13_RAT	sp|Q5I0K7|ALG13_RAT UDP-N-acetylglucosamine transferase subunit ALG13 homolog OS=Rattus norvegicus GN=Alg13 PE=1 SV=1	9031.ENSGALP00000012955	asparagine-linked glycosylation 13 homolog (S. cerevisiae)	COG5017	KOG3349	_	PF04101.13|Glyco_tran_28_C|Glycosyltransferase family 28 C-terminal domain|ENSGALT00000089579|m.16527:3-229
ENSGALG00000030773	1.089497453	2.758880825	-1.332458697	0.000906455	0.001921863	down	yes	1.061464325	1.463141143	0.743886892	2.323739078	3.879000611	2.073902785	9	24039075	24062914	+	CP	protein_coding	GO:0006825|copper ion transport; GO:0006879|cellular iron ion homeostasis; GO:0043687|post-translational protein modification; GO:0044267|cellular protein metabolic process	GO:0005576|extracellular region; GO:0005615|extracellular space; GO:0005765|lysosomal membrane; GO:0005788|endoplasmic reticulum lumen; GO:0070062|extracellular exosome; GO:0072562|blood microparticle	GO:0004322|ferroxidase activity; GO:0005507|copper ion binding; GO:0051087|chaperone binding	ko:K13624|CP	ko00860|Porphyrin and chlorophyll metabolism; ko04216|Ferroptosis	4359	XP_015147339.1	XP_015147339.1 ceruloplasmin [Gallus gallus]	sp|P00450|CERU_HUMAN	sp|P00450|CERU_HUMAN Ceruloplasmin OS=Homo sapiens GN=CP PE=1 SV=1	9031.ENSGALP00000016972	Putative uncharacterized protein 	_	KOG1263	_	PF05805.9|L6_membrane|L6 membrane protein|ENSGALT00000104594|m.9407:2-103;PF07732.12|Cu-oxidase_3|Multicopper oxidase|ENSGALT00000104594|m.9407:207-317;PF07732.12|Cu-oxidase_3|Multicopper oxidase|ENSGALT00000104594|m.9407:561-669;PF07732.12|Cu-oxidase_3|Multicopper oxidase|ENSGALT00000104594|m.9407:915-1011;PF07731.11|Cu-oxidase_2|Multicopper oxidase|ENSGALT00000104594|m.9407:421-469;PF07731.11|Cu-oxidase_2|Multicopper oxidase|ENSGALT00000104594|m.9407:1064-1168;PF00394.19|Cu-oxidase|Multicopper oxidase|ENSGALT00000104594|m.9407:343-472
ENSGALG00000030781	8.952827658	18.71155585	-1.062674473	9.47E-20	8.75E-19	down	yes	8.117842608	9.202553048	9.538087319	20.4055714	16.43199414	19.29710201	2	122766240	122822370	+	CA2	protein_coding	GO:0006730|one-carbon metabolic process; GO:0071244|cellular response to carbon dioxide	GO:0005623|cell; GO:0005737|cytoplasm; GO:0005886|plasma membrane	GO:0004089|carbonate dehydratase activity; GO:0008270|zinc ion binding	ko:K18245|CA2	ko00910|Nitrogen metabolism; ko04964|Proximal tubule bicarbonate reclamation; ko04966|Collecting duct acid secretion; ko04971|Gastric acid secretion; ko04972|Pancreatic secretion; ko04976|Bile secretion	1759	NP_990648.1	NP_990648.1 carbonic anhydrase 2 [Gallus gallus]	sp|P07630|CAH2_CHICK	sp|P07630|CAH2_CHICK Carbonic anhydrase 2 OS=Gallus gallus GN=CA2 PE=2 SV=3	9031.ENSGALP00000025525	Carbonic anhydrase 2 (EC 4.2.1.1)(Carbonic anhydrase II)(CA-II)(Carbonate dehydratase II); E [...] 	COG3338	KOG0382	_	PF00194.18|Carb_anhydrase|Eukaryotic-type carbonic anhydrase|ENSGALT00000052439|m.2056:4-258
ENSGALG00000030853	0.133973254	0.363284236	-1.374473759	0.003526747	0.006782379	down	yes	0.066012389	0.154881092	0.181026281	0.283067023	0.349842626	0.456943059	1	45996281	46037126	+	ENSGALG00000030853	protein_coding	GO:0007283|spermatogenesis; GO:0030154|cell differentiation; GO:0060271|cilium assembly; GO:0060294|cilium movement involved in cell motility	GO:0005737|cytoplasm; GO:0005930|axoneme	--	--	--	3745	XP_003640413.2	XP_003640413.2 cilia- and flagella-associated protein 54 isoform X1 [Gallus gallus]	sp|Q96N23|CFA54_HUMAN	sp|Q96N23|CFA54_HUMAN Cilia- and flagella-associated protein 54 OS=Homo sapiens GN=CFAP54 PE=2 SV=3	9031.ENSGALP00000018667	annotation not avaliable	_	_	NOG43692	_
ENSGALG00000030858	3.24455634	16.8448502	-2.372631011	6.88E-77	5.23E-75	down	yes	3.174161994	3.152431376	3.40707565	17.83335028	15.66929344	17.03190688	10	20298566	20337526	+	FRMD5	protein_coding	GO:0030334|regulation of cell migration; GO:0031032|actomyosin structure organization; GO:0045785|positive regulation of cell adhesion; GO:2000146|negative regulation of cell motility	GO:0005856|cytoskeleton; GO:0005912|adherens junction; GO:0016021|integral component of membrane	GO:0005178|integrin binding; GO:0005200|structural constituent of cytoskeleton; GO:0008092|cytoskeletal protein binding; GO:0019901|protein kinase binding	--	--	1826	XP_413944.3	XP_413944.3 FERM domain-containing protein 5 isoform X1 [Gallus gallus]	sp|Q7Z6J6|FRMD5_HUMAN	sp|Q7Z6J6|FRMD5_HUMAN FERM domain-containing protein 5 OS=Homo sapiens GN=FRMD5 PE=1 SV=1	9544.ENSMMUP00000029990	FERM domain containing 5	_	KOG3530	_	PF09379.7|FERM_N|FERM N-terminal domain|ENSGALT00000046841|m.5950:21-82;PF00373.15|FERM_M|FERM central domain|ENSGALT00000046841|m.5950:102-209;PF09380.7|FERM_C|FERM C-terminal PH-like domain|ENSGALT00000046841|m.5950:216-301;PF08736.8|FA|FERM adjacent (FA)|ENSGALT00000046841|m.5950:309-344
ENSGALG00000030863	0.215737282	0.56691351	-1.353710338	0.004838967	0.009088953	down	yes	0.287275361	0.122867817	0.237068669	0.585314744	0.48286951	0.632556278	10	1337596	1344427	+	ENSGALG00000030863	protein_coding	--	GO:0005887|integral component of plasma membrane	GO:0005415|nucleoside:sodium symporter activity	ko:K11536|SLC28A	--	2201	XP_413724.2	XP_413724.2 sodium/nucleoside cotransporter 1 [Gallus gallus]	sp|Q9MZT2|S28A1_RABIT	sp|Q9MZT2|S28A1_RABIT Sodium/nucleoside cotransporter 1 OS=Oryctolagus cuniculus GN=SLC28A1 PE=2 SV=1	9031.ENSGALP00000003966	"solute carrier family 28 (sodium-coupled nucleoside transporter), member 2"	COG1972	KOG3747	_	PF07662.10|Nucleos_tra2_C|Na+ dependent nucleoside transporter C-terminus|ENSGALT00000046776|m.5082:366-589;PF01773.17|Nucleos_tra2_N|Na+ dependent nucleoside transporter N-terminus|ENSGALT00000046776|m.5082:183-254;PF07670.11|Gate|Nucleoside recognition|ENSGALT00000046776|m.5082:264-359
ENSGALG00000030886	6.024316536	1.516338312	1.983115607	8.20E-15	5.39E-14	up	yes	7.550919673	4.728115919	5.793914016	1.471962026	1.395088412	1.681964496	17	872551	874786	-	PTGDS	protein_coding	GO:0006629|lipid metabolic process	GO:0005576|extracellular region	GO:0005215|transporter activity; GO:0036094|small molecule binding	ko:K01830|PTGDS	ko00590|Arachidonic acid metabolism; ko01100|Metabolic pathways	956	POI30188.1	POI30188.1 hypothetical protein CIB84_006064 [Bambusicola thoracicus]	sp|Q01584|LIPO_RHIMB	sp|Q01584|LIPO_RHIMB Lipocalin OS=Rhinella marina PE=1 SV=1	_	_	_	_	_	PF00061.20|Lipocalin|Lipocalin / cytosolic fatty-acid binding protein family|ENSGALT00000053882|m.11672:35-178
ENSGALG00000030889	6.485840994	17.8357695	-1.457993888	1.47E-29	2.24E-28	down	yes	5.626938494	7.109781786	6.720802703	15.06252887	19.09983796	19.34494168	3	3366094	3369593	+	FOXA2	protein_coding	"GO:0000432|positive regulation of transcription from RNA polymerase II promoter by glucose; GO:0000433|carbon catabolite repression of transcription from RNA polymerase II promoter by glucose; GO:0001708|cell fate specification; GO:0006351|transcription, DNA-templated; GO:0006357|regulation of transcription by RNA polymerase II; GO:0008344|adult locomotory behavior; GO:0009653|anatomical structure morphogenesis; GO:0010719|negative regulation of epithelial to mesenchymal transition; GO:0016569|covalent chromatin modification; GO:0030193|regulation of blood coagulation; GO:0031018|endocrine pancreas development; GO:0033132|negative regulation of glucokinase activity; GO:0040019|positive regulation of embryonic development; GO:0043433|negative regulation of DNA-binding transcription factor activity; GO:0045893|positive regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0061178|regulation of insulin secretion involved in cellular response to glucose stimulus; GO:0070741|response to interleukin-6; GO:0071542|dopaminergic neuron differentiation; GO:0090009|primitive streak formation; GO:2000049|positive regulation of cell-cell adhesion mediated by cadherin; GO:2000543|positive regulation of gastrulation; GO:2000971|negative regulation of detection of glucose"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0030054|cell junction	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity; GO:0008134|transcription factor binding; GO:0019904|protein domain specific binding; GO:0044212|transcription regulatory region DNA binding"	"ko:K08035|FOXA2,HNF3B"	ko04212|Longevity regulating pathway - worm; ko04213|Longevity regulating pathway - multiple species; ko04950|Maturity onset diabetes of the young	1929	BAB21581.1	BAB21581.1 transcription factor Foxa2 [Gallus gallus]	sp|Q9Y261|FOXA2_HUMAN	sp|Q9Y261|FOXA2_HUMAN Hepatocyte nuclear factor 3-beta OS=Homo sapiens GN=FOXA2 PE=1 SV=1	59729.ENSTGUP00000007741	Hepatocyte nuclear factor 3-beta (HNF-3-beta)(HNF-3B)(Forkhead box protein A2) [Taeniopygia  [...] 	COG5025	KOG3563	_	PF00250.15|Forkhead|Forkhead domain|ENSGALT00000049347|m.10638:151-235;PF09354.7|HNF_C|HNF3 C-terminal domain|ENSGALT00000049347|m.10638:351-427;PF08430.9|Forkhead_N|Forkhead N-terminal region|ENSGALT00000049347|m.10638:17-150
ENSGALG00000030943	57.31266253	26.57074689	1.108723978	2.95E-26	3.93E-25	up	yes	59.34142074	58.94993951	53.64662734	25.2716671	31.30928015	23.13129341	1	67188237	67209122	-	KRAS	protein_coding	GO:0007165|signal transduction; GO:0008284|positive regulation of cell population proliferation	GO:0005737|cytoplasm; GO:0031234|extrinsic component of cytoplasmic side of plasma membrane	GO:0003924|GTPase activity; GO:0005525|GTP binding	"ko:K07827|KRAS,KRAS2"	ko01521|EGFR tyrosine kinase inhibitor resistance; ko01522|Endocrine resistance; ko04010|MAPK signaling pathway; ko04012|ErbB signaling pathway; ko04013|MAPK signaling pathway - fly; ko04014|Ras signaling pathway; ko04015|Rap1 signaling pathway; ko04062|Chemokine signaling pathway; ko04068|FoxO signaling pathway; ko04071|Sphingolipid signaling pathway; ko04072|Phospholipase D signaling pathway; ko04137|Mitophagy - animal; ko04138|Autophagy - yeast; ko04140|Autophagy - animal; ko04150|mTOR signaling pathway; ko04151|PI3K-Akt signaling pathway; ko04210|Apoptosis; ko04211|Longevity regulating pathway; ko04213|Longevity regulating pathway - multiple species; ko04214|Apoptosis - fly; ko04320|Dorso-ventral axis formation; ko04360|Axon guidance; ko04370|VEGF signaling pathway; ko04371|Apelin signaling pathway; ko04540|Gap junction; ko04550|Signaling pathways regulating pluripotency of stem cells; ko04650|Natural killer cell mediated cytotoxicity; ko04660|T cell receptor signaling pathway; ko04662|B cell receptor signaling pathway; ko04664|Fc epsilon RI signaling pathway; ko04720|Long-term potentiation; ko04722|Neurotrophin signaling pathway; ko04725|Cholinergic synapse; ko04726|Serotonergic synapse; ko04730|Long-term depression; ko04810|Regulation of actin cytoskeleton; ko04910|Insulin signaling pathway; ko04912|GnRH signaling pathway; ko04914|Progesterone-mediated oocyte maturation; ko04915|Estrogen signaling pathway; ko04916|Melanogenesis; ko04917|Prolactin signaling pathway; ko04919|Thyroid hormone signaling pathway; ko04921|Oxytocin signaling pathway; ko04933|AGE-RAGE signaling pathway in diabetic complications; ko04960|Aldosterone-regulated sodium reabsorption; ko05034|Alcoholism; ko05160|Hepatitis C; ko05161|Hepatitis B; ko05166|HTLV-I infection; ko05200|Pathways in cancer; ko05203|Viral carcinogenesis; ko05205|Proteoglycans in cancer; ko05206|MicroRNAs in cancer; ko05210|Colorectal cancer; ko05211|Renal cell carcinoma; ko05212|Pancreatic cancer; ko05213|Endometrial cancer; ko05214|Glioma; ko05215|Prostate cancer; ko05216|Thyroid cancer; ko05218|Melanoma; ko05219|Bladder cancer; ko05220|Chronic myeloid leukemia; ko05221|Acute myeloid leukemia; ko05223|Non-small cell lung cancer; ko05224|Breast cancer; ko05230|Central carbon metabolism in cancer; ko05231|Choline metabolism in cancer	1112	EPQ11217.1	EPQ11217.1 GTPase KRas [Myotis brandtii]	sp|P79800|RASK_MELGA	sp|P79800|RASK_MELGA GTPase KRas OS=Meleagris gallopavo GN=KRAS PE=2 SV=1	9031.ENSGALP00000022686	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	COG1100	KOG0395	_	"PF00071.19|Ras|Ras family|ENSGALT00000063299|m.2016:5-164;PF08477.10|Roc|Ras of Complex, Roc, domain of DAPkinase|ENSGALT00000063299|m.2016:5-120;PF00025.18|Arf|ADP-ribosylation factor family|ENSGALT00000063299|m.2016:3-162;PF00009.24|GTP_EFTU|Elongation factor Tu GTP binding domain|ENSGALT00000063299|m.2016:45-160;PF01926.20|MMR_HSR1|50S ribosome-binding GTPase|ENSGALT00000063299|m.2016:6-117"
ENSGALG00000030996	2.73179799	9.739881654	-1.830262427	1.13E-11	5.79E-11	down	yes	2.960173545	2.604482177	2.630738248	7.868478339	10.84883711	10.50232951	15	6953787	6954986	+	ENSGALG00000030996	protein_coding	GO:0006084|acetyl-CoA metabolic process; GO:0006633|fatty acid biosynthetic process; GO:0006768|biotin metabolic process; GO:0006853|carnitine shuttle; GO:0010629|negative regulation of gene expression; GO:0010884|positive regulation of lipid storage; GO:0010906|regulation of glucose metabolic process; GO:0014070|response to organic cyclic compound; GO:0031325|positive regulation of cellular metabolic process; GO:0031667|response to nutrient levels; GO:0031999|negative regulation of fatty acid beta-oxidation; GO:0042493|response to drug; GO:0043086|negative regulation of catalytic activity; GO:0045540|regulation of cholesterol biosynthetic process; GO:0051289|protein homotetramerization; GO:0060421|positive regulation of heart growth; GO:0097009|energy homeostasis; GO:2001295|malonyl-CoA biosynthetic process	GO:0005634|nucleus; GO:0005739|mitochondrion; GO:0005741|mitochondrial outer membrane; GO:0005829|cytosol; GO:0012505|endomembrane system	GO:0003989|acetyl-CoA carboxylase activity; GO:0004075|biotin carboxylase activity; GO:0005524|ATP binding; GO:0009374|biotin binding; GO:0042802|identical protein binding; GO:0046872|metal ion binding	ko:K01946|ACACB	ko00061|Fatty acid biosynthesis; ko00254|Aflatoxin biosynthesis; ko00620|Pyruvate metabolism; ko00640|Propanoate metabolism; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko04152|AMPK signaling pathway; ko04910|Insulin signaling pathway; ko04920|Adipocytokine signaling pathway; ko04922|Glucagon signaling pathway; ko04931|Insulin resistance	534	XP_025011460.1	XP_025011460.1 LOW QUALITY PROTEIN: acetyl-CoA carboxylase 2 [Gallus gallus]	sp|O00763|ACACB_HUMAN	sp|O00763|ACACB_HUMAN Acetyl-CoA carboxylase 2 OS=Homo sapiens GN=ACACB PE=1 SV=3	_	_	_	_	_	"PF00289.19|Biotin_carb_N|Biotin carboxylase, N-terminal domain|ENSGALT00000074835|m.10654:55-168"
ENSGALG00000031035	3.949355748	8.717345211	-1.140277165	1.01E-16	7.62E-16	down	yes	4.033379027	4.24736429	3.567323927	10.73204173	7.622636941	7.797356966	2	109465995	109509669	-	PCMTD1	protein_coding	--	GO:0005737|cytoplasm	GO:0004719|protein-L-isoaspartate (D-aspartate) O-methyltransferase activity	--	--	3757	NP_001026190.1	NP_001026190.1 protein-L-isoaspartate O-methyltransferase domain-containing protein 1 [Gallus gallus]	sp|Q5ZMR3|PCMD1_CHICK	sp|Q5ZMR3|PCMD1_CHICK Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 OS=Gallus gallus GN=PCMTD1 PE=2 SV=1	_	_	_	_	_	PF01135.16|PCMT|Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)|ENSGALT00000102538|m.1757:10-221;PF08123.10|DOT1|Histone methylation protein DOT1|ENSGALT00000102538|m.1757:68-136
ENSGALG00000031067	4.28077326	2.039330063	1.066085304	1.42E-13	8.48E-13	up	yes	4.508328479	4.255844584	4.078146717	1.743493953	2.072769394	2.301726841	5	277276	281735	+	TMEM132A	protein_coding	--	GO:0000139|Golgi membrane; GO:0005783|endoplasmic reticulum; GO:0005789|endoplasmic reticulum membrane; GO:0005794|Golgi apparatus; GO:0016021|integral component of membrane; GO:0070062|extracellular exosome	--	ko:K17599|TMEM132	--	3740	XP_025006791.1	XP_025006791.1 LOW QUALITY PROTEIN: transmembrane protein 132A [Gallus gallus]	sp|Q922P8|T132A_MOUSE	sp|Q922P8|T132A_MOUSE Transmembrane protein 132A OS=Mus musculus GN=Tmem132a PE=1 SV=2	_	_	_	_	_	"PF16070.2|TMEM132|Transmembrane protein family 132|ENSGALT00000094889|m.2062:390-454;PF15705.2|TMEM132D_N|Mature oligodendrocyte transmembrane protein, TMEM132D, N-term|ENSGALT00000094889|m.2062:89-162;PF15706.2|TMEM132D_C|Mature oligodendrocyte transmembrane protein, TMEM132D, C-term|ENSGALT00000094889|m.2063:141-215;PF16070.2|TMEM132|Transmembrane protein family 132|ENSGALT00000094889|m.2064:6-72"
ENSGALG00000031122	1.080617138	0.520154229	1.040660706	0.001071599	0.002246379	up	yes	0.896488117	1.150285266	1.19507803	0.649133834	0.460925106	0.450403747	8	1215190	1359430	+	NTNG1	protein_coding	GO:0006501|C-terminal protein lipidation; GO:0007409|axonogenesis	GO:0005576|extracellular region; GO:0005886|plasma membrane; GO:0046658|anchored component of plasma membrane	--	ko:K07522|NTNG1	ko04360|Axon guidance; ko04514|Cell adhesion molecules (CAMs)	2351	XP_015145834.1	XP_015145834.1 netrin-G1 isoform X6 [Gallus gallus]	sp|Q9Y2I2|NTNG1_HUMAN	sp|Q9Y2I2|NTNG1_HUMAN Netrin-G1 OS=Homo sapiens GN=NTNG1 PE=1 SV=3	9031.ENSGALP00000002928	annotation not avaliable	_	KOG1836;KOG3512	_	PF00055.14|Laminin_N|Laminin N-terminal (Domain VI)|ENSGALT00000070081|m.6868:50-295;PF00053.21|Laminin_EGF|Laminin EGF domain|ENSGALT00000070081|m.6868:297-341;PF00053.21|Laminin_EGF|Laminin EGF domain|ENSGALT00000070081|m.6868:364-405
ENSGALG00000031167	9.78541901	20.78349317	-1.08595303	3.88E-26	5.12E-25	down	yes	9.257748509	10.58240878	9.516099742	19.20711113	23.1771392	19.96622917	2	115326115	115356284	+	ENSGALG00000031167	protein_coding	GO:0032467|positive regulation of cytokinesis; GO:0051781|positive regulation of cell division	GO:0000922|spindle pole; GO:0005737|cytoplasm; GO:0005813|centrosome; GO:0005819|spindle; GO:0005874|microtubule	--	ko:K16771|CSPP1	--	2334	XP_015711162.1	XP_015711162.1 PREDICTED: centrosome and spindle pole-associated protein 1 isoform X3 [Coturnix japonica]	sp|Q1MSJ5|CSPP1_HUMAN	sp|Q1MSJ5|CSPP1_HUMAN Centrosome and spindle pole-associated protein 1 OS=Homo sapiens GN=CSPP1 PE=1 SV=4	_	_	_	_	_	_
ENSGALG00000031186	0.424594902	1.496993427	-1.793929969	0.000484077	0.001070872	down	yes	0.421528713	0.103021739	0.749234253	1.761747351	1.352228196	1.377004733	1	49517079	49526710	-	ENSGALG00000031186	protein_coding	GO:0007141|male meiosis I; GO:0007276|gamete generation; GO:0007286|spermatid development; GO:0045141|meiotic telomere clustering; GO:0051321|meiotic cell cycle	GO:0005623|cell	--	--	--	1125	XP_015716456.1	XP_015716456.1 PREDICTED: meiosis inhibitor protein 1 isoform X1 [Coturnix japonica]	sp|Q9D4I2|MEII1_MOUSE	sp|Q9D4I2|MEII1_MOUSE Meiosis inhibitor protein 1 OS=Mus musculus GN=Mei1 PE=2 SV=3	9031.ENSGALP00000019421	meiosis inhibitor 1	_	_	NOG73841	_
ENSGALG00000031212	19.60681998	7.784326862	1.331594851	5.39E-28	7.72E-27	up	yes	20.35042064	17.71694319	20.75309611	8.744372292	7.062392377	7.546215917	5	57745609	57747045	+	MGAT2	protein_coding	GO:0006486|protein glycosylation; GO:0009312|oligosaccharide biosynthetic process	GO:0000139|Golgi membrane; GO:0005795|Golgi stack; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0016021|integral component of membrane	"GO:0008455|alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity"	ko:K00736|MGAT2	ko00510|N-Glycan biosynthesis; ko00513|Various types of N-glycan biosynthesis; ko01100|Metabolic pathways	1437	XP_015132222.1	"XP_015132222.1 alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase [Gallus gallus]"	sp|O19071|MGAT2_PIG	"sp|O19071|MGAT2_PIG Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Sus scrofa GN=MGAT2 PE=3 SV=1"	9258.ENSOANP00000022065	"mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase"	_	KOG2791	_	PF05060.11|MGAT2|N-acetylglucosaminyltransferase II (MGAT2)|ENSGALT00000059615|m.4134:121-471
ENSGALG00000031275	94.40760647	41.28564762	1.193066174	8.01E-45	2.44E-43	up	yes	101.5802805	89.98697669	91.6555622	37.6956193	46.80333767	39.35798589	2	97238238	97246235	-	TUBB6	protein_coding	GO:0007017|microtubule-based process	GO:0005737|cytoplasm; GO:0005874|microtubule	GO:0003924|GTPase activity; GO:0005200|structural constituent of cytoskeleton; GO:0005525|GTP binding	ko:K07375|TUBB	ko04145|Phagosome; ko04540|Gap junction; ko05130|Pathogenic Escherichia coli infection	1968	NP_001026183.1	NP_001026183.1 tubulin beta-5 chain [Gallus gallus]	sp|P09653|TBB5_CHICK	sp|P09653|TBB5_CHICK Tubulin beta-5 chain OS=Gallus gallus PE=3 SV=1	_	_	_	_	_	"PF00091.22|Tubulin|Tubulin/FtsZ family, GTPase domain|ENSGALT00000074135|m.1484:20-228;PF03953.14|Tubulin_C|Tubulin C-terminal domain|ENSGALT00000074135|m.1484:278-398;PF10644.6|Misat_Tub_SegII|Misato Segment II tubulin-like domain|ENSGALT00000074135|m.1484:19-88"
ENSGALG00000031305	1.287642522	3.303044185	-1.352264444	5.13E-16	3.69E-15	down	yes	1.331599666	1.32826295	1.20306495	3.47120658	3.245589354	3.19233662	6	1278454	1365241	+	FAM13C	protein_coding	--	--	--	--	--	2708	XP_421488.4	XP_421488.4 protein FAM13C isoform X4 [Gallus gallus]	sp|Q9DBR2|FA13C_MOUSE	sp|Q9DBR2|FA13C_MOUSE Protein FAM13C OS=Mus musculus GN=Fam13c PE=1 SV=2	9031.ENSGALP00000002817	"family with sequence similarity 13, member C1"	_	_	NOG119761	_
ENSGALG00000031313	0.942612486	1.953270585	-1.04329766	0.000201098	0.000471087	down	yes	0.71358463	0.983617637	1.130635191	2.039943101	1.907807965	1.912060689	10	2064918	2075635	-	ENSGALG00000031313	protein_coding	"GO:0000381|regulation of alternative mRNA splicing, via spliceosome; GO:0006397|mRNA processing"	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005829|cytosol	GO:0003723|RNA binding	"ko:K13207|CUGBP,BRUNOL,CELF"	--	1398	XP_425051.5	XP_425051.5 CUGBP Elav-like family member 6 isoform X2 [Gallus gallus]	sp|Q96J87|CELF6_HUMAN	sp|Q96J87|CELF6_HUMAN CUGBP Elav-like family member 6 OS=Homo sapiens GN=CELF6 PE=1 SV=1	9031.ENSGALP00000039322	CUG-BP and ETR-3-like factor 6 Fragment 	_	KOG0146	_	"PF00076.19|RRM_1|RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)|ENSGALT00000048878|m.5161:44-111;PF00076.19|RRM_1|RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)|ENSGALT00000048878|m.5161:133-172;PF00076.19|RRM_1|RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)|ENSGALT00000048878|m.5161:382-452"
ENSGALG00000031325	6.680061309	3.099711354	1.105238758	6.85E-09	2.74E-08	up	yes	5.846545503	6.853415373	7.340223051	2.619995847	2.797582259	3.881555955	32	208994	283021	+	TGFB1	protein_coding	GO:0007179|transforming growth factor beta receptor signaling pathway; GO:0010862|positive regulation of pathway-restricted SMAD protein phosphorylation; GO:0016049|cell growth; GO:0030509|BMP signaling pathway; GO:0033686|positive regulation of luteinizing hormone secretion; GO:0042327|positive regulation of phosphorylation; GO:0042701|progesterone secretion; GO:0042981|regulation of apoptotic process; GO:0043408|regulation of MAPK cascade; GO:0046881|positive regulation of follicle-stimulating hormone secretion; GO:0048468|cell development; GO:0050708|regulation of protein secretion; GO:0051781|positive regulation of cell division; GO:0060395|SMAD protein signal transduction	GO:0005615|extracellular space	GO:0005114|type II transforming growth factor beta receptor binding; GO:0005125|cytokine activity; GO:0008083|growth factor activity	ko:K13375|TGFB1	ko04010|MAPK signaling pathway; ko04060|Cytokine-cytokine receptor interaction; ko04068|FoxO signaling pathway; ko04110|Cell cycle; ko04144|Endocytosis; ko04350|TGF-beta signaling pathway; ko04380|Osteoclast differentiation; ko04390|Hippo signaling pathway; ko04659|Th17 cell differentiation; ko04672|Intestinal immune network for IgA production; ko04932|Non-alcoholic fatty liver disease (NAFLD); ko04933|AGE-RAGE signaling pathway in diabetic complications; ko05140|Leishmaniasis; ko05142|Chagas disease (American trypanosomiasis); ko05144|Malaria; ko05145|Toxoplasmosis; ko05146|Amoebiasis; ko05152|Tuberculosis; ko05161|Hepatitis B; ko05166|HTLV-I infection; ko05200|Pathways in cancer; ko05205|Proteoglycans in cancer; ko05210|Colorectal cancer; ko05211|Renal cell carcinoma; ko05212|Pancreatic cancer; ko05220|Chronic myeloid leukemia; ko05321|Inflammatory bowel disease (IBD); ko05323|Rheumatoid arthritis; ko05410|Hypertrophic cardiomyopathy (HCM); ko05414|Dilated cardiomyopathy	1460	NP_001305385.1	NP_001305385.1 transforming growth factor beta-1 proprotein precursor [Gallus gallus]	sp|P09531|TGFB1_CHICK	sp|P09531|TGFB1_CHICK Transforming growth factor beta-1 (Fragment) OS=Gallus gallus GN=TGFB1 PE=2 SV=2	_	_	_	_	_	PF00688.15|TGFb_propeptide|TGF-beta propeptide|ENSGALT00000057396|m.14354:71-309;PF00019.17|TGF_beta|Transforming growth factor beta like domain|ENSGALT00000057396|m.14354:343-441
ENSGALG00000031450	4.249286002	17.36864754	-2.028632299	9.34E-130	2.69E-127	down	yes	4.444212006	4.260664702	4.042981298	17.42037268	16.0371545	18.64841543	1	194597369	194675601	-	MYO7A	protein_coding	GO:0001845|phagolysosome assembly; GO:0006886|intracellular protein transport; GO:0007040|lysosome organization; GO:0007601|visual perception; GO:0007605|sensory perception of sound; GO:0030048|actin filament-based movement; GO:0042462|eye photoreceptor cell development; GO:0048563|post-embryonic animal organ morphogenesis; GO:0050953|sensory perception of light stimulus; GO:0050957|equilibrioception; GO:0051904|pigment granule transport; GO:0060088|auditory receptor cell stereocilium organization	GO:0001750|photoreceptor outer segment; GO:0001917|photoreceptor inner segment; GO:0005737|cytoplasm; GO:0005765|lysosomal membrane; GO:0005829|cytosol; GO:0005902|microvillus; GO:0005938|cell cortex; GO:0016324|apical plasma membrane; GO:0031477|myosin VII complex; GO:0032391|photoreceptor connecting cilium; GO:0032420|stereocilium; GO:0042470|melanosome; GO:0045202|synapse; GO:1990435|upper tip-link density	GO:0000146|microfilament motor activity; GO:0005516|calmodulin binding; GO:0005524|ATP binding; GO:0019904|protein domain specific binding; GO:0030507|spectrin binding; GO:0030898|actin-dependent ATPase activity; GO:0042803|protein homodimerization activity; GO:0043531|ADP binding; GO:0047485|protein N-terminus binding; GO:0051015|actin filament binding	ko:K10359|MYO7	--	6592	XP_015707985.1	XP_015707985.1 PREDICTED: unconventional myosin-VIIa isoform X2 [Coturnix japonica]	sp|Q13402|MYO7A_HUMAN	sp|Q13402|MYO7A_HUMAN Unconventional myosin-VIIa OS=Homo sapiens GN=MYO7A PE=1 SV=2	9031.ENSGALP00000001044	myosin VIIA	COG5022	KOG4229	_	PF00063.18|Myosin_head|Myosin head (motor domain)|ENSGALT00000092359|m.4821:67-735;PF00784.14|MyTH4|MyTH4 domain|ENSGALT00000092359|m.4821:1160-1257;PF00784.14|MyTH4|MyTH4 domain|ENSGALT00000092359|m.4821:1762-1863;PF00373.15|FERM_M|FERM central domain|ENSGALT00000092359|m.4821:1362-1447;PF00373.15|FERM_M|FERM central domain|ENSGALT00000092359|m.4821:1982-2083;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000092359|m.4821:752-770;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000092359|m.4821:774-793;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000092359|m.4821:820-840;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000092359|m.4821:844-863
ENSGALG00000031487	27.14060304	64.86414852	-1.256659456	2.55E-62	1.35E-60	down	yes	24.67624229	29.05072789	27.69483894	60.12666275	70.65444622	63.8113366	13	16943722	17130245	+	FSTL4	protein_coding	GO:0031549|negative regulation of brain-derived neurotrophic factor receptor signaling pathway; GO:0048671|negative regulation of collateral sprouting; GO:0061000|negative regulation of dendritic spine development	GO:0005576|extracellular region; GO:0030141|secretory granule	GO:0005509|calcium ion binding; GO:0048403|brain-derived neurotrophic factor binding	--	--	5134	XP_025010566.1	XP_025010566.1 follistatin-related protein 4 isoform X1 [Gallus gallus]	sp|Q6MZW2|FSTL4_HUMAN	sp|Q6MZW2|FSTL4_HUMAN Follistatin-related protein 4 OS=Homo sapiens GN=FSTL4 PE=2 SV=3	_	_	_	_	_	PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000051204|m.9032:342-419;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000051204|m.9032:257-326;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000051204|m.9032:343-431;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000051204|m.9032:343-422;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000051204|m.9032:355-424;PF13202.3|EF-hand_5|EF hand|ENSGALT00000051204|m.9032:183-206;PF13202.3|EF-hand_5|EF hand|ENSGALT00000051204|m.9032:228-242;PF07648.12|Kazal_2|Kazal-type serine protease inhibitor domain|ENSGALT00000051204|m.9032:99-134;PF00050.18|Kazal_1|Kazal-type serine protease inhibitor domain|ENSGALT00000051204|m.9032:96-137
ENSGALG00000031496	85.70028795	39.78225639	1.106980675	1.81E-60	9.06E-59	up	yes	85.87487465	81.76529857	89.46069064	40.2593974	41.05043611	38.03693568	13	11260862	11270908	+	SPIK5	protein_coding	GO:0045071|negative regulation of viral genome replication; GO:0051412|response to corticosterone	GO:0005576|extracellular region; GO:0005615|extracellular space; GO:0032991|protein-containing complex	GO:0002020|protease binding; GO:0004867|serine-type endopeptidase inhibitor activity; GO:0008200|ion channel inhibitor activity; GO:0019870|potassium channel inhibitor activity; GO:0030414|peptidase inhibitor activity	--	--	1701	NP_001025783.2	NP_001025783.2 ovoinhibitor precursor [Gallus gallus]	sp|P10184|IOV7_CHICK	sp|P10184|IOV7_CHICK Ovoinhibitor OS=Gallus gallus GN=OIH PE=1 SV=2	9031.ENSGALP00000033955	Ovoinhibitor Precursor ; Seems to have at least five active inhibitory domains; two for tryp [...] 	_	KOG3649	_	PF00050.18|Kazal_1|Kazal-type serine protease inhibitor domain|ENSGALT00000005545|m.8756:73-130;PF00050.18|Kazal_1|Kazal-type serine protease inhibitor domain|ENSGALT00000005545|m.8756:144-195;PF00050.18|Kazal_1|Kazal-type serine protease inhibitor domain|ENSGALT00000005545|m.8756:204-261;PF00050.18|Kazal_1|Kazal-type serine protease inhibitor domain|ENSGALT00000005545|m.8756:270-327;PF00050.18|Kazal_1|Kazal-type serine protease inhibitor domain|ENSGALT00000005545|m.8756:336-392;PF00050.18|Kazal_1|Kazal-type serine protease inhibitor domain|ENSGALT00000005545|m.8756:401-458;PF00050.18|Kazal_1|Kazal-type serine protease inhibitor domain|ENSGALT00000005545|m.8756:467-517;PF07648.12|Kazal_2|Kazal-type serine protease inhibitor domain|ENSGALT00000005545|m.8756:90-130;PF07648.12|Kazal_2|Kazal-type serine protease inhibitor domain|ENSGALT00000005545|m.8756:155-195;PF07648.12|Kazal_2|Kazal-type serine protease inhibitor domain|ENSGALT00000005545|m.8756:221-261;PF07648.12|Kazal_2|Kazal-type serine protease inhibitor domain|ENSGALT00000005545|m.8756:287-327;PF07648.12|Kazal_2|Kazal-type serine protease inhibitor domain|ENSGALT00000005545|m.8756:352-392;PF07648.12|Kazal_2|Kazal-type serine protease inhibitor domain|ENSGALT00000005545|m.8756:418-458;PF07648.12|Kazal_2|Kazal-type serine protease inhibitor domain|ENSGALT00000005545|m.8756:477-505
ENSGALG00000031518	48.75888395	155.0413361	-1.668713096	1.91E-11	9.64E-11	down	yes	58.01211042	43.62881854	44.63572289	186.9442837	112.9984031	165.1813217	33	4132597	4133942	-	ENSGALG00000031518	protein_coding	--	--	--	"ko:K04452|DDIT3,GADD153"	ko04010|MAPK signaling pathway; ko04141|Protein processing in endoplasmic reticulum; ko04210|Apoptosis; ko04932|Non-alcoholic fatty liver disease (NAFLD); ko05202|Transcriptional misregulation in cancer	812	XP_015128659.1	XP_015128659.1 uncharacterized protein DDIT3 [Gallus gallus]	_	_	_	_	_	_	_	PF15358.3|TSKS|Testis-specific serine kinase substrate|ENSGALT00000050399|m.14948:57-147
ENSGALG00000031534	59.05498601	127.5267493	-1.110537963	4.46E-85	4.05E-83	down	yes	57.07290717	62.09986799	57.99218286	130.1142854	128.9545612	123.5114014	6	8972573	9078848	-	ARID5B	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006357|regulation of transcription by RNA polymerase II; GO:0051091|positive regulation of DNA-binding transcription factor activity; GO:0060612|adipose tissue development"	GO:0005634|nucleus	GO:0003713|transcription coactivator activity; GO:0044212|transcription regulatory region DNA binding	--	--	4354	XP_015143606.1	XP_015143606.1 AT-rich interactive domain-containing protein 5B isoform X1 [Gallus gallus]	sp|Q5ZJ69|ARI5B_CHICK	sp|Q5ZJ69|ARI5B_CHICK AT-rich interactive domain-containing protein 5B OS=Gallus gallus GN=ARID5B PE=2 SV=1	9031.ENSGALP00000004725	AT-rich interactive domain-containing protein 5B (ARID domain-containing protein 5B); DNA-bi [...] 	_	KOG2744	_	PF01388.18|ARID|ARID/BRIGHT DNA binding domain|ENSGALT00000053154|m.4431:327-412
ENSGALG00000031571	339.6474426	111.0900161	1.612221441	8.39E-118	1.78E-115	up	yes	338.457176	344.7399761	335.7451756	119.2304183	105.0404955	108.9991345	1	48086441	48086884	-	H2A-VII	protein_coding	GO:0006342|chromatin silencing	GO:0000786|nucleosome; GO:0000790|nuclear chromatin	GO:0003677|DNA binding; GO:0046982|protein heterodimerization activity	--	--	444	EOB06731.1	"EOB06731.1 Histone H2A-IV, partial [Anas platyrhynchos]"	sp|P02263|H2A4_CHICK	sp|P02263|H2A4_CHICK Histone H2A-IV OS=Gallus gallus PE=1 SV=2	9031.ENSGALP00000037316	Histone H2A-IV 	COG5262	KOG1756	_	PF16211.2|Histone_H2A_C|C-terminus of histone H2A|ENSGALT00000058977|m.1171:95-128;PF00125.21|Histone|Core histone H2A/H2B/H3/H4|ENSGALT00000058977|m.1171:8-92;PF00808.20|CBFD_NFYB_HMF|Histone-like transcription factor (CBF/NF-Y) and archaeal histone|ENSGALT00000058977|m.1171:28-91
ENSGALG00000031593	60.43590339	27.46892166	1.137319176	3.24E-33	6.04E-32	up	yes	59.17858055	58.06574392	64.0633857	28.09272804	28.28615071	26.02788625	4	1985097	1986199	+	TMSB15B	protein_coding	GO:0007015|actin filament organization	GO:0005737|cytoplasm; GO:0005856|cytoskeleton	GO:0003785|actin monomer binding	--	--	666	OPJ89424.1	OPJ89424.1 thymosin beta-15B [Patagioenas fasciata monilis]	sp|Q9DET5|TB15A_COTJA	sp|Q9DET5|TB15A_COTJA Thymosin beta-15A homolog OS=Coturnix japonica PE=3 SV=3	_	_	_	_	_	_
ENSGALG00000031631	4.640786901	1.743865669	1.406936584	3.95E-13	2.28E-12	up	yes	4.787138503	4.2978785	4.837343701	1.727176598	1.880416218	1.62400419	3	82667795	82674292	-	SDHAF4	protein_coding	GO:0003407|neural retina development; GO:0034553|mitochondrial respiratory chain complex II assembly; GO:0045087|innate immune response; GO:0045333|cellular respiration	"GO:0005749|mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone); GO:0005759|mitochondrial matrix"	GO:0008177|succinate dehydrogenase (ubiquinone) activity	--	--	1616	XP_419887.1	"XP_419887.1 succinate dehydrogenase assembly factor 4, mitochondrial isoform X1 [Gallus gallus]"	sp|Q5VUM1|SDHF4_HUMAN	"sp|Q5VUM1|SDHF4_HUMAN Succinate dehydrogenase assembly factor 4, mitochondrial OS=Homo sapiens GN=SDHAF4 PE=3 SV=1"	9031.ENSGALP00000025678	chromosome 6 open reading frame 57	_	KOG3245	_	PF07896.9|DUF1674|Protein of unknown function (DUF1674)|ENSGALT00000092936|m.12734:64-107
ENSGALG00000031648	6.238479322	16.30693783	-1.384793303	1.15E-24	1.42E-23	down	yes	5.910859355	6.166445463	6.638133148	15.08072673	18.98231296	14.85777381	2	115362443	115376865	+	ENSGALG00000031648	protein_coding	GO:0032467|positive regulation of cytokinesis; GO:0051781|positive regulation of cell division	GO:0000922|spindle pole; GO:0005737|cytoplasm; GO:0005813|centrosome; GO:0005819|spindle; GO:0005874|microtubule	--	ko:K16771|CSPP1	--	1560	XP_025003511.1	XP_025003511.1 centrosome and spindle pole-associated protein 1 [Gallus gallus]	sp|Q1MSJ5|CSPP1_HUMAN	sp|Q1MSJ5|CSPP1_HUMAN Centrosome and spindle pole-associated protein 1 OS=Homo sapiens GN=CSPP1 PE=1 SV=4	_	_	_	_	_	_
ENSGALG00000031656	0.0918815	1.10273707	-3.449148721	7.77E-19	6.83E-18	down	yes	0.040866925	0.099878884	0.134898692	0.958189243	1.249916983	1.100104985	3	56480470	56633286	-	EYA4	protein_coding	"GO:0006281|DNA repair; GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated; GO:0007275|multicellular organism development; GO:0007601|visual perception; GO:0007605|sensory perception of sound; GO:0009653|anatomical structure morphogenesis; GO:0016576|histone dephosphorylation; GO:0030154|cell differentiation; GO:0045739|positive regulation of DNA repair; GO:2001240|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand"	GO:0005634|nucleus; GO:0005737|cytoplasm	GO:0004725|protein tyrosine phosphatase activity; GO:0046872|metal ion binding	ko:K17622|EYA4	--	2861	XP_015139523.1	XP_015139523.1 eyes absent homolog 4 isoform X13 [Gallus gallus]	sp|O95677|EYA4_HUMAN	sp|O95677|EYA4_HUMAN Eyes absent homolog 4 OS=Homo sapiens GN=EYA4 PE=1 SV=2	_	_	_	_	_	PF00702.23|Hydrolase|haloacid dehalogenase-like hydrolase|ENSGALT00000074069|m.12166:376-620
ENSGALG00000031734	0.56566399	2.32655242	-2.021082531	2.64E-12	1.42E-11	down	yes	0.36305298	0.780826229	0.55311276	2.28513279	2.469681375	2.224843096	1	194448531	194462713	-	AQP11	protein_coding	GO:0048388|endosomal lumen acidification; GO:0051260|protein homooligomerization; GO:0072014|proximal tubule development	GO:0005783|endoplasmic reticulum; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0009986|cell surface; GO:0016021|integral component of membrane; GO:0030425|dendrite	GO:0005215|transporter activity	ko:K09870|AQP11	--	2177	XP_015136362.2	XP_015136362.2 aquaporin-11 [Gallus gallus]	sp|Q8NBQ7|AQP11_HUMAN	sp|Q8NBQ7|AQP11_HUMAN Aquaporin-11 OS=Homo sapiens GN=AQP11 PE=2 SV=1	_	_	_	_	_	PF00230.17|MIP|Major intrinsic protein|ENSGALT00000062691|m.4816:111-278
ENSGALG00000031786	0.192603422	0.426200558	-1.10633307	0.020669265	0.03428703	down	yes	0.220530717	0.069297134	0.287982416	0.432536626	0.330186564	0.515878483	2	51589935	51620997	+	BLVRA	protein_coding	GO:0042167|heme catabolic process; GO:0055114|oxidation-reduction process	GO:0005829|cytosol; GO:0070062|extracellular exosome	GO:0004074|biliverdin reductase activity; GO:0008270|zinc ion binding	"ko:K00214|BLVRA,bvdR"	ko00860|Porphyrin and chlorophyll metabolism; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites	3325	XP_025003498.1	XP_025003498.1 biliverdin reductase A [Gallus gallus]	sp|P53004|BIEA_HUMAN	sp|P53004|BIEA_HUMAN Biliverdin reductase A OS=Homo sapiens GN=BLVRA PE=1 SV=2	9031.ENSGALP00000020151	biliverdin reductase A	COG0673	_	_	"PF09166.7|Biliv-reduc_cat|Biliverdin reductase, catalytic|ENSGALT00000056614|m.745:128-240;PF01408.19|GFO_IDH_MocA|Oxidoreductase family, NAD-binding Rossmann fold|ENSGALT00000056614|m.745:4-120"
ENSGALG00000031869	0.129742768	0.511248828	-1.899198616	7.89E-08	2.84E-07	down	yes	0.099145053	0.132169525	0.157913724	0.383103202	0.57034918	0.580294102	2	110575597	110697739	+	ENSGALG00000031869	protein_coding	GO:0007601|visual perception; GO:0035082|axoneme assembly; GO:0035556|intracellular signal transduction; GO:0035845|photoreceptor cell outer segment organization; GO:0042461|photoreceptor cell development; GO:0045494|photoreceptor cell maintenance; GO:0046548|retinal rod cell development; GO:0046549|retinal cone cell development	GO:0001750|photoreceptor outer segment; GO:0001917|photoreceptor inner segment; GO:0005737|cytoplasm; GO:0005875|microtubule associated complex	GO:0008017|microtubule binding	ko:K19538|RP1	--	5787	XP_021244709.1	XP_021244709.1 lipoxygenase homology domain-containing protein 1 isoform X1 [Numida meleagris]	sp|Q8MJ06|RP1_PAPHA	sp|Q8MJ06|RP1_PAPHA Oxygen-regulated protein 1 OS=Papio hamadryas GN=RP1 PE=2 SV=1	_	_	_	_	_	PF01477.20|PLAT|PLAT/LH2 domain|ENSGALT00000100606|m.1780:279-381;PF01477.20|PLAT|PLAT/LH2 domain|ENSGALT00000100606|m.1780:406-513;PF01477.20|PLAT|PLAT/LH2 domain|ENSGALT00000100606|m.1780:871-975;PF01477.20|PLAT|PLAT/LH2 domain|ENSGALT00000100606|m.1780:996-1097;PF01477.20|PLAT|PLAT/LH2 domain|ENSGALT00000100606|m.1780:1134-1207;PF01477.20|PLAT|PLAT/LH2 domain|ENSGALT00000100606|m.1780:1235-1350;PF01477.20|PLAT|PLAT/LH2 domain|ENSGALT00000100606|m.1780:1371-1475;PF01477.20|PLAT|PLAT/LH2 domain|ENSGALT00000100606|m.1780:1500-1605;PF01477.20|PLAT|PLAT/LH2 domain|ENSGALT00000100606|m.1780:1757-1860;PF03607.14|DCX|Doublecortin|ENSGALT00000100606|m.1780:59-115;PF03607.14|DCX|Doublecortin|ENSGALT00000100606|m.1780:184-239
ENSGALG00000031874	38.52005395	16.29721185	1.24047407	2.01E-27	2.83E-26	up	yes	40.45213326	36.30234371	38.80568489	17.42814546	15.93580771	15.52768239	1	48151569	48152313	+	HIST1H101	protein_coding	GO:0006334|nucleosome assembly	GO:0000786|nucleosome; GO:0005634|nucleus	GO:0003677|DNA binding	ko:K11275|H1_5	--	663	NP_001035732.1	NP_001035732.1 histone H1.01 [Gallus gallus]	sp|P08284|H101_CHICK	sp|P08284|H101_CHICK Histone H1.01 OS=Gallus gallus PE=1 SV=2	9031.ENSGALP00000019193	Histone H1.01 ; Histones H1 are necessary for the condensation of nucleosome chains into hig [...] 	_	KOG4012	_	PF00538.16|Linker_histone|linker histone H1 and H5 family|ENSGALT00000051001|m.1203:39-109
ENSGALG00000031920	0.951972259	0.412103665	1.188397935	0.013288775	0.022925225	up	yes	0.722377834	0.903517271	1.230021671	0.255737519	0.537784081	0.442789395	2	66892969	66897037	+	FOXF2	protein_coding	"GO:0030154|cell differentiation; GO:0030198|extracellular matrix organization; GO:0042249|establishment of planar polarity of embryonic epithelium; GO:0045892|negative regulation of transcription, DNA-templated; GO:0045893|positive regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0048566|embryonic digestive tract development; GO:0048596|embryonic camera-type eye morphogenesis; GO:0048806|genitalia development; GO:0060021|roof of mouth development"	GO:0005634|nucleus; GO:0005667|transcription factor complex	"GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding; GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity; GO:0008134|transcription factor binding; GO:0043565|sequence-specific DNA binding"	ko:K09399|FOXF	--	1240	XP_015137672.2	XP_015137672.2 forkhead box protein F2 [Gallus gallus]	sp|O54743|FOXF2_MOUSE	sp|O54743|FOXF2_MOUSE Forkhead box protein F2 OS=Mus musculus GN=Foxf2 PE=2 SV=2	59729.ENSTGUP00000002195	Forkhead box protein F2 (Forkhead-related transcription factor 2)(Forkhead-related activator [...] 	_	KOG2294	_	PF00250.15|Forkhead|Forkhead domain|ENSGALT00000048076|m.1015:97-181
ENSGALG00000031947	4.273058443	15.48481132	-1.855071919	1.09E-44	3.30E-43	down	yes	4.647403303	3.881368104	4.290403923	17.09908553	14.72859294	14.62675548	2	75831410	75998658	-	FBXL7	protein_coding	GO:0000086|G2/M transition of mitotic cell cycle; GO:0000278|mitotic cell cycle; GO:0008283|cell population proliferation; GO:0016567|protein ubiquitination; GO:0031146|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0051301|cell division	GO:0005737|cytoplasm; GO:0005813|centrosome; GO:0019005|SCF ubiquitin ligase complex	GO:0004842|ubiquitin-protein transferase activity	--	--	1585	XP_426048.4	XP_426048.4 F-box/LRR-repeat protein 7 isoform X1 [Gallus gallus]	sp|Q5BJ29|FBXL7_MOUSE	sp|Q5BJ29|FBXL7_MOUSE F-box/LRR-repeat protein 7 OS=Mus musculus GN=Fbxl7 PE=1 SV=1	_	_	_	_	_	PF13516.3|LRR_6|Leucine Rich repeat|ENSGALT00000095357|m.1104:249-272;PF13516.3|LRR_6|Leucine Rich repeat|ENSGALT00000095357|m.1104:304-325;PF13516.3|LRR_6|Leucine Rich repeat|ENSGALT00000095357|m.1104:327-351;PF13516.3|LRR_6|Leucine Rich repeat|ENSGALT00000095357|m.1104:353-377;PF13516.3|LRR_6|Leucine Rich repeat|ENSGALT00000095357|m.1104:379-399;PF12937.4|F-box-like|F-box-like|ENSGALT00000095357|m.1104:68-112;PF00646.30|F-box|F-box domain|ENSGALT00000095357|m.1104:68-110
ENSGALG00000031973	39.85430829	18.15463897	1.133964944	4.31E-66	2.50E-64	up	yes	40.46655141	39.54448882	39.55188464	18.30137167	17.06356063	19.0989846	33	6965630	6981019	+	ANKRD52	protein_coding	--	--	--	ko:K15504|ANKRD52	--	4112	XP_015742376.1	XP_015742376.1 PREDICTED: serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C [Coturnix japonica]	sp|Q5ZLC8|ANR52_CHICK	sp|Q5ZLC8|ANR52_CHICK Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C OS=Gallus gallus GN=ANKRD52 PE=2 SV=1	9031.ENSGALP00000023054	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (Serine/threonine [...] 	COG0666	KOG0504;KOG4177	_	PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000068724|m.15594:17-86;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000068724|m.15594:93-182;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000068724|m.15594:126-218;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000068724|m.15594:192-283;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000068724|m.15594:225-316;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000068724|m.15594:291-380;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000068724|m.15594:325-410;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000068724|m.15594:386-468;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000068724|m.15594:442-515;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000068724|m.15594:546-627;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000068724|m.15594:603-695;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000068724|m.15594:699-760;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000068724|m.15594:767-828;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000068724|m.15594:837-902;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000068724|m.15594:904-960;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000068724|m.15594:26-76;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000068724|m.15594:90-140;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000068724|m.15594:155-208;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000068724|m.15594:189-240;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000068724|m.15594:222-266;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000068724|m.15594:425-458;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000068724|m.15594:438-489;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000068724|m.15594:542-584;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000068724|m.15594:601-651;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000068724|m.15594:667-722;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000068724|m.15594:735-788;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000068724|m.15594:806-856;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000068724|m.15594:839-892;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000068724|m.15594:872-925;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000068724|m.15594:905-957;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000068724|m.15594:57-86;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000068724|m.15594:91-120;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000068724|m.15594:155-185;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000068724|m.15594:191-218;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000068724|m.15594:254-284;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000068724|m.15594:287-317;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000068724|m.15594:353-381;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000068724|m.15594:438-468;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000068724|m.15594:471-501;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000068724|m.15594:504-562;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000068724|m.15594:667-695;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000068724|m.15594:701-729;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000068724|m.15594:805-827;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000068724|m.15594:905-936;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000068724|m.15594:978-1005;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000068724|m.15594:43-96;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000068724|m.15594:207-261;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000068724|m.15594:273-328;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000068724|m.15594:426-475;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000068724|m.15594:458-511;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000068724|m.15594:891-946;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000068724|m.15594:155-181;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000068724|m.15594:221-248;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000068724|m.15594:254-281;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000068724|m.15594:287-315;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000068724|m.15594:353-379;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000068724|m.15594:701-726
ENSGALG00000031991	2.680923576	1.266864598	1.075495872	1.70E-06	5.30E-06	up	yes	2.737199434	2.634078566	2.671492727	1.147566761	1.262977767	1.390049267	Z	20606613	20610669	+	SHLD3	protein_coding	--	--	--	--	--	1848	POI33386.1	POI33386.1 hypothetical protein CIB84_002862 [Bambusicola thoracicus]	sp|Q6ZNX1|YE028_HUMAN	sp|Q6ZNX1|YE028_HUMAN Uncharacterized protein FLJ26957 OS=Homo sapiens PE=2 SV=1	9031.ENSGALP00000032231	annotation not avaliable	_	_	NOG74505	_
ENSGALG00000032061	10.78786249	5.276972874	1.030231919	2.85E-20	2.72E-19	up	yes	11.24920664	10.30098377	10.81339705	5.266313854	5.200153375	5.364451392	Z	1753936	1756904	+	IER3IP1	protein_coding	GO:0006888|endoplasmic reticulum to Golgi vesicle-mediated transport; GO:2000269|regulation of fibroblast apoptotic process	GO:0005783|endoplasmic reticulum; GO:0005789|endoplasmic reticulum membrane; GO:0005794|Golgi apparatus; GO:0016020|membrane; GO:0030134|COPII-coated ER to Golgi transport vesicle; GO:0030173|integral component of Golgi membrane	--	--	--	1634	NP_001289095.1	NP_001289095.1 immediate early response 3-interacting protein 1 precursor [Gallus gallus]	sp|Q9CR20|IR3IP_MOUSE	sp|Q9CR20|IR3IP_MOUSE Immediate early response 3-interacting protein 1 OS=Mus musculus GN=Ier3ip1 PE=3 SV=1	_	_	_	_	_	_
ENSGALG00000032079	6431.21682	1626.665758	1.983167262	6.20E-18	5.08E-17	up	yes	8373.642065	5900.461968	5019.546428	1614.773232	1636.026924	1629.197118	MT	14893	16035	+	CYTB	protein_coding	"GO:0006122|mitochondrial electron transport, ubiquinol to cytochrome c; GO:0006979|response to oxidative stress; GO:0022904|respiratory electron transport chain"	GO:0005737|cytoplasm; GO:0005739|mitochondrion; GO:0005750|mitochondrial respiratory chain complex III; GO:0031305|integral component of mitochondrial inner membrane	GO:0008121|ubiquinol-cytochrome-c reductase activity; GO:0020037|heme binding; GO:0046872|metal ion binding	"ko:K00412|CYTB,petB"	ko00190|Oxidative phosphorylation; ko01100|Metabolic pathways; ko02020|Two-component system; ko04260|Cardiac muscle contraction; ko04932|Non-alcoholic fatty liver disease (NAFLD); ko05010|Alzheimer's disease; ko05012|Parkinson's disease; ko05016|Huntington's disease	1143	NP_006926.1	NP_006926.1 cytochrome b (mitochondrion) [Gallus gallus]	sp|P18946|CYB_CHICK	sp|P18946|CYB_CHICK Cytochrome b OS=Gallus gallus GN=MT-CYB PE=1 SV=1	9031.ENSGALP00000034623	Cytochrome b (Ubiquinol-cytochrome-c reductase complex cytochrome b subunit)(Cytochrome b-c1 [...] 	COG1290	KOG4663	_	_
ENSGALG00000032087	12.2030408	5.457390065	1.159498235	2.62E-11	1.30E-10	up	yes	14.33111421	11.77165581	10.50635237	4.701595692	6.136677248	5.533897254	2	96558292	96559269	-	MC5R	protein_coding	--	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0004977|melanocortin receptor activity	ko:K04203|MC5R	ko04080|Neuroactive ligand-receptor interaction	978	XP_015137951.1	XP_015137951.1 melanocortin receptor 5 isoform X1 [Gallus gallus]	sp|Q9TT23|MC5R_PANTR	sp|Q9TT23|MC5R_PANTR Melanocortin receptor 5 OS=Pan troglodytes GN=MC5R PE=3 SV=1	9031.ENSGALP00000030308	melanocortin 5-receptor 	_	KOG3656	_	PF00001.18|7tm_1|7 transmembrane receptor (rhodopsin family)|ENSGALT00000077234|m.1462:53-295;PF13853.3|7tm_4|Olfactory receptor|ENSGALT00000077234|m.1462:46-213;PF10320.6|7TM_GPCR_Srsx|Serpentine type 7TM GPCR chemoreceptor Srsx|ENSGALT00000077234|m.1462:48-309
ENSGALG00000032108	5.539519768	2.633778602	1.069761566	1.12E-10	5.30E-10	up	yes	5.732179062	4.944516079	5.941864162	2.807221142	2.11591881	2.978195855	24	3817531	3820521	-	TMEM136-1	protein_coding	--	GO:0016021|integral component of membrane	--	--	--	2344	XP_019478575.1	XP_019478575.1 PREDICTED: transmembrane protein 136-like isoform X1 [Meleagris gallopavo]	sp|Q6ZRR5|TM136_HUMAN	sp|Q6ZRR5|TM136_HUMAN Transmembrane protein 136 OS=Homo sapiens GN=TMEM136 PE=2 SV=2	9031.ENSGALP00000040050	transmembrane protein 136	_	KOG4474	_	PF03798.13|TRAM_LAG1_CLN8|TLC domain|ENSGALT00000057703|m.6219:32-188
ENSGALG00000032142	10550.92021	1608.089257	2.713941836	8.31E-30	1.30E-28	up	yes	13691.20766	9508.372476	8453.180491	1644.813932	1750.271793	1429.182045	MT	6645	8192	+	COX1	protein_coding	"GO:0006123|mitochondrial electron transport, cytochrome c to oxygen; GO:0009060|aerobic respiration; GO:0015990|electron transport coupled proton transport"	GO:0005739|mitochondrion; GO:0005750|mitochondrial respiratory chain complex III; GO:0005751|mitochondrial respiratory chain complex IV; GO:0045277|respiratory chain complex IV	GO:0004129|cytochrome-c oxidase activity; GO:0005506|iron ion binding; GO:0020037|heme binding	ko:K02256|COX1	ko00190|Oxidative phosphorylation; ko01100|Metabolic pathways; ko04260|Cardiac muscle contraction; ko04932|Non-alcoholic fatty liver disease (NAFLD); ko05010|Alzheimer's disease; ko05012|Parkinson's disease; ko05016|Huntington's disease	1548	NP_006917.1	NP_006917.1 cytochrome c oxidase subunit I (mitochondrion) [Gallus gallus]	sp|P18943|COX1_CHICK	sp|P18943|COX1_CHICK Cytochrome c oxidase subunit 1 OS=Gallus gallus GN=MT-CO1 PE=3 SV=1	9031.ENSGALP00000034614	Cytochrome c oxidase subunit 1 (EC 1.9.3.1)(Cytochrome c oxidase polypeptide I); Cytochrome  [...] 	COG0843	KOG4769	_	_
ENSGALG00000032239	45.86080226	21.10750966	1.119136429	2.11E-37	4.76E-36	up	yes	42.36774629	48.56543436	46.64922615	21.08474224	20.5250682	21.71271855	5	1225084	1232835	+	GCHFR	protein_coding	GO:0009890|negative regulation of biosynthetic process; GO:0043105|negative regulation of GTP cyclohydrolase I activity; GO:0051291|protein heterooligomerization	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0030425|dendrite; GO:0031965|nuclear membrane; GO:0032991|protein-containing complex; GO:0042470|melanosome	GO:0004857|enzyme inhibitor activity; GO:0016597|amino acid binding; GO:0030742|GTP-dependent protein binding; GO:0044549|GTP cyclohydrolase binding	--	--	1128	NP_001186451.1	NP_001186451.1 GTP cyclohydrolase 1 feedback regulatory protein [Gallus gallus]	sp|P99025|GFRP_MOUSE	sp|P99025|GFRP_MOUSE GTP cyclohydrolase 1 feedback regulatory protein OS=Mus musculus GN=Gchfr PE=1 SV=3	9031.ENSGALP00000007089	GTP cyclohydrolase I feedback regulator	_	_	NOG41956	PF06399.10|GFRP|GTP cyclohydrolase I feedback regulatory protein (GFRP)|ENSGALT00000077588|m.2208:34-116
ENSGALG00000032352	24.23972013	8.256282031	1.552657605	5.81E-11	2.81E-10	up	yes	25.29172277	23.52329718	23.90414045	6.606552568	9.447073697	8.71521983	20	12553717	12553941	-	ENSGALG00000032352	protein_coding	--	--	--	--	--	225	EOB08063.1	"EOB08063.1 hypothetical protein Anapl_00298, partial [Anas platyrhynchos]"	_	_	_	_	_	_	_	_
ENSGALG00000032398	18.15575808	8.86940535	1.032686604	6.59E-43	1.86E-41	up	yes	16.1122229	19.47398343	18.88106791	8.634903961	9.365517082	8.607795007	8	2987284	3025151	+	ASPM	protein_coding	GO:0007051|spindle organization; GO:0051301|cell division	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005819|spindle	GO:0005516|calmodulin binding	"ko:K16743|ASPM,ASP"	--	10911	XP_422197.5	XP_422197.5 abnormal spindle-like microcephaly-associated protein isoform X2 [Gallus gallus]	sp|P62292|ASPM_MACMU	sp|P62292|ASPM_MACMU Abnormal spindle-like microcephaly-associated protein homolog OS=Macaca mulatta GN=ASPM PE=3 SV=1	_	_	_	_	_	"PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:1193-1213;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:1242-1261;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:1275-1293;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:1392-1410;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:1464-1484;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:1510-1529;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:1561-1578;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:1582-1601;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:1604-1623;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:1656-1674;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:1728-1744;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:1750-1770;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:1800-1820;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:1898-1916;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:1947-1966;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:1970-1988;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:2020-2038;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:2092-2112;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:2115-2135;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:2165-2184;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:2193-2207;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:2240-2258;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:2334-2354;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:2407-2426;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:2459-2475;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:2481-2500;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:2531-2550;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:2553-2573;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:2603-2623;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:2649-2668;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:2698-2716;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:2744-2762;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:2767-2784;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:2817-2835;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:2867-2883;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:2889-2907;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000103738|m.6958:3003-3019;PF15780.2|ASH|Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin|ENSGALT00000103738|m.6958:40-136;PF00307.28|CH|Calponin homology (CH) domain|ENSGALT00000103738|m.6958:1035-1182;PF11971.5|CAMSAP_CH|CAMSAP CH domain|ENSGALT00000103738|m.6958:1052-1092"
ENSGALG00000032405	0.609529487	1.535055183	-1.31841351	5.90E-07	1.93E-06	down	yes	0.755545542	0.397410856	0.675632064	1.414807236	1.649981241	1.540377071	16	1729257	1745689	+	ZNF226L	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated"	GO:0016607|nuclear speck	GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity; GO:0046872|metal ion binding	ko:K09228|KRAB	--	2193	XP_015128418.1	XP_015128418.1 zinc finger protein 501 isoform X3 [Gallus gallus]	sp|Q6ZSS3|ZN621_HUMAN	sp|Q6ZSS3|ZN621_HUMAN Zinc finger protein 621 OS=Homo sapiens GN=ZNF621 PE=2 SV=1	9031.ENSGALP00000022429	hypothetical LOC430731	COG5048	KOG1721	_	"PF00096.23|zf-C2H2|Zinc finger, C2H2 type|ENSGALT00000103613|m.11313:191-212;PF00096.23|zf-C2H2|Zinc finger, C2H2 type|ENSGALT00000103613|m.11313:274-296;PF00096.23|zf-C2H2|Zinc finger, C2H2 type|ENSGALT00000103613|m.11313:302-324;PF00096.23|zf-C2H2|Zinc finger, C2H2 type|ENSGALT00000103613|m.11313:386-408;PF13894.3|zf-C2H2_4|C2H2-type zinc finger|ENSGALT00000103613|m.11313:302-324;PF13894.3|zf-C2H2_4|C2H2-type zinc finger|ENSGALT00000103613|m.11313:386-408;PF01352.24|KRAB|KRAB box|ENSGALT00000103613|m.11313:38-78;PF13912.3|zf-C2H2_6|C2H2-type zinc finger|ENSGALT00000103613|m.11313:442-460"
ENSGALG00000032456	13985.13671	4011.215448	1.801780429	5.81E-14	3.59E-13	up	yes	18375.24699	12616.03995	10964.12318	4208.605794	3805.030728	4020.00982	MT	8331	9014	+	COII	protein_coding	GO:0006979|response to oxidative stress; GO:0022904|respiratory electron transport chain; GO:0042773|ATP synthesis coupled electron transport	GO:0005739|mitochondrion; GO:0005751|mitochondrial respiratory chain complex IV; GO:0016021|integral component of membrane; GO:0045277|respiratory chain complex IV; GO:0070062|extracellular exosome	GO:0004129|cytochrome-c oxidase activity; GO:0005507|copper ion binding	ko:K02261|COX2	ko00190|Oxidative phosphorylation; ko01100|Metabolic pathways; ko04260|Cardiac muscle contraction; ko04932|Non-alcoholic fatty liver disease (NAFLD); ko05010|Alzheimer's disease; ko05012|Parkinson's disease; ko05016|Huntington's disease	684	AMP87944.1	AMP87944.1 cytochrome c oxidase subunit II (mitochondrion) [Gallus gallus]	sp|P18944|COX2_CHICK	sp|P18944|COX2_CHICK Cytochrome c oxidase subunit 2 OS=Gallus gallus GN=MT-CO2 PE=3 SV=1	9031.ENSGALP00000034615	Cytochrome c oxidase subunit 2 (EC 1.9.3.1)(Cytochrome c oxidase polypeptide II); Cytochrome [...] 	COG1622	KOG4767	_	_
ENSGALG00000032465	7824.741342	2178.762551	1.844529309	1.28E-29	1.97E-28	up	yes	9187.09056	7999.403928	6287.729536	2088.751684	2278.159296	2169.376674	MT	9085	9249	+	ATP8	protein_coding	GO:0015986|ATP synthesis coupled proton transport	"GO:0000276|mitochondrial proton-transporting ATP synthase complex, coupling factor F(o); GO:0016021|integral component of membrane"	GO:0015078|proton transmembrane transporter activity	"ko:K02125|ATPeF08,MTATP8,ATP8"	ko00190|Oxidative phosphorylation; ko01100|Metabolic pathways; ko05010|Alzheimer's disease; ko05012|Parkinson's disease; ko05016|Huntington's disease	165	NP_006919.1	NP_006919.1 ATP synthase F0 subunit 8 (mitochondrion) [Gallus gallus]	sp|P14093|ATP8_CHICK	sp|P14093|ATP8_CHICK ATP synthase protein 8 OS=Gallus gallus GN=MT-ATP8 PE=3 SV=1	9031.ENSGALP00000034616	ATP synthase protein 8 (F-ATPase subunit 8)(A6L); Mitochondrial membrane ATP synthase (F(1)F [...] 	_	_	NOG115960	_
ENSGALG00000032467	5.491566959	2.676500557	1.034114449	3.87E-11	1.90E-10	up	yes	6.311251508	5.253186523	4.910262848	2.906207268	2.540491084	2.582803319	24	6229478	6236297	-	C11orf52	protein_coding	--	--	--	--	--	2207	XP_001234251.1	XP_001234251.1 uncharacterized protein C11orf52 homolog [Gallus gallus]	_	_	_	_	_	_	_	PF15147.3|DUF4578|Domain of unknown function (DUF4578)|ENSGALT00000071922|m.6476:12-129
ENSGALG00000032499	49.55911724	22.32844725	1.149912659	1.00E-20	9.75E-20	up	yes	52.76437295	42.8242314	53.08874736	23.56857766	24.46207007	18.95469403	1	195634141	195636411	-	ANAPC15	protein_coding	GO:0007049|cell cycle; GO:0051301|cell division; GO:0090266|regulation of mitotic cell cycle spindle assembly checkpoint	GO:0005680|anaphase-promoting complex	--	--	--	719	NP_001269050.1	NP_001269050.1 anaphase-promoting complex subunit 15 [Meleagris gallopavo]	sp|P60007|APC15_MOUSE	sp|P60007|APC15_MOUSE Anaphase-promoting complex subunit 15 OS=Mus musculus GN=Anapc15 PE=2 SV=1	_	_	_	_	_	PF15243.3|ANAPC15|Anaphase-promoting complex subunit 15|ENSGALT00000055189|m.4870:2-93
ENSGALG00000032506	0.208115538	1.614137343	-2.896509181	6.31E-12	3.28E-11	down	yes	0.314573666	0.249866159	0.05990679	1.272007882	1.814352389	1.756051757	2	125926904	125935308	-	GEM	protein_coding	GO:0000278|mitotic cell cycle; GO:0007165|signal transduction; GO:0051276|chromosome organization; GO:0051310|metaphase plate congression; GO:1901842|negative regulation of high voltage-gated calcium channel activity	GO:0005634|nucleus; GO:0009898|cytoplasmic side of plasma membrane; GO:0030496|midbody; GO:0051233|spindle midzone; GO:0072686|mitotic spindle	GO:0000287|magnesium ion binding; GO:0003924|GTPase activity; GO:0005525|GTP binding; GO:0019003|GDP binding	ko:K07846|GEM	--	2010	OXB69397.1	OXB69397.1 hypothetical protein ASZ78_004887 [Callipepla squamata]	sp|P55041|GEM_MOUSE	sp|P55041|GEM_MOUSE GTP-binding protein GEM OS=Mus musculus GN=Gem PE=1 SV=2	9031.ENSGALP00000025664	GTP binding protein overexpressed in skeletal muscle 	COG1100	KOG0395	_	"PF00071.19|Ras|Ras family|ENSGALT00000061235|m.2126:78-240;PF08477.10|Roc|Ras of Complex, Roc, domain of DAPkinase|ENSGALT00000061235|m.2126:78-195"
ENSGALG00000032526	7.653861206	3.198180399	1.256316165	3.17E-36	6.69E-35	up	yes	7.581534437	8.106213833	7.273835348	3.059497379	3.28967102	3.245372799	9	16457646	16473512	-	B3GNT5	protein_coding	GO:0006486|protein glycosylation; GO:0007417|central nervous system development	GO:0000139|Golgi membrane; GO:0005622|intracellular; GO:0016021|integral component of membrane	"GO:0008378|galactosyltransferase activity; GO:0008457|beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity; GO:0047256|lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity"	ko:K03766|B3GNT5	ko00601|Glycosphingolipid biosynthesis - lacto and neolacto series; ko01100|Metabolic pathways	4580	NP_001107233.1	"NP_001107233.1 lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase [Gallus gallus]"	sp|Q864U8|B3GN5_PIG	"sp|Q864U8|B3GN5_PIG Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase OS=Sus scrofa GN=B3GNT5 PE=2 SV=1"	9031.ENSGALP00000014231	"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 (EC:2.4.1.-)"	_	KOG2287	_	PF01762.18|Galactosyl_T|Galactosyltransferase|ENSGALT00000058942|m.9167:102-293
ENSGALG00000032588	2.685175842	0.642222112	2.046944144	7.67E-13	4.33E-12	up	yes	3.232767508	2.037987392	2.784772627	0.761420336	0.501859858	0.663386142	14	4766374	4772041	+	ARPC1B	protein_coding	GO:0034314|Arp2/3 complex-mediated actin nucleation	GO:0005737|cytoplasm; GO:0005885|Arp2/3 protein complex; GO:0036195|muscle cell projection membrane; GO:0070062|extracellular exosome	GO:0051015|actin filament binding	ko:K05757|ARPC1A_B	ko04144|Endocytosis; ko04666|Fc gamma R-mediated phagocytosis; ko04810|Regulation of actin cytoskeleton; ko05100|Bacterial invasion of epithelial cells; ko05130|Pathogenic Escherichia coli infection; ko05131|Shigellosis; ko05132|Salmonella infection	1529	POI21500.1	POI21500.1 hypothetical protein CIB84_014753 [Bambusicola thoracicus]	sp|Q9R0Q6|ARC1A_MOUSE	sp|Q9R0Q6|ARC1A_MOUSE Actin-related protein 2/3 complex subunit 1A OS=Mus musculus GN=Arpc1a PE=1 SV=1	9544.ENSMMUP00000001943	"actin related protein 2/3 complex, subunit 1B, 41kDa"	COG2319	KOG1523	_	_
ENSGALG00000032598	0.91725181	0.297922226	1.590395171	1.93E-10	8.94E-10	up	yes	0.933871213	0.814050275	1.003833942	0.339564833	0.295474121	0.258727725	33	6846579	6855524	+	MYO1A	protein_coding	GO:0016197|endosomal transport; GO:0030048|actin filament-based movement; GO:0045056|transcytosis	GO:0005737|cytoplasm; GO:0005884|actin filament; GO:0005902|microvillus; GO:0016328|lateral plasma membrane; GO:0016459|myosin complex; GO:0030027|lamellipodium	GO:0000146|microfilament motor activity; GO:0003779|actin binding; GO:0005516|calmodulin binding; GO:0005524|ATP binding; GO:0016887|ATPase activity	ko:K10356|MYO1	--	4794	XP_015155878.1	XP_015155878.1 unconventional myosin-Ia isoform X1 [Gallus gallus]	sp|P47807|MYO1A_CHICK	sp|P47807|MYO1A_CHICK Unconventional myosin-Ia OS=Gallus gallus GN=MYO1A PE=1 SV=2	28377.ENSACAP00000007334	myosin IA	COG5022	KOG0164	_	"PF00063.18|Myosin_head|Myosin head (motor domain)|ENSGALT00000099992|m.15487:20-690;PF06017.10|Myosin_TH1|Unconventional myosin tail, actin- and lipid-binding|ENSGALT00000099992|m.15487:885-1071;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000099992|m.15487:710-727;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000099992|m.15487:734-750;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000099992|m.15487:754-772"
ENSGALG00000032645	93.71985649	24.64317681	1.926735109	1.67E-67	1.01E-65	up	yes	95.1141711	94.10639662	91.93900175	29.23823008	23.43957199	21.25172835	1	48169497	48170081	-	H2A-VII	protein_coding	GO:0006342|chromatin silencing	GO:0000786|nucleosome; GO:0000790|nuclear chromatin	GO:0003677|DNA binding; GO:0046982|protein heterodimerization activity	--	--	585	XP_025002825.1	XP_025002825.1 histone H2A-IV isoform X1 [Gallus gallus]	sp|P02263|H2A4_CHICK	sp|P02263|H2A4_CHICK Histone H2A-IV OS=Gallus gallus PE=1 SV=2	9031.ENSGALP00000037265	Histone H2A-IV 	COG5262	KOG1756	_	PF16211.2|Histone_H2A_C|C-terminus of histone H2A|ENSGALT00000046827|m.1211:104-137;PF00125.21|Histone|Core histone H2A/H2B/H3/H4|ENSGALT00000046827|m.1211:16-101;PF00808.20|CBFD_NFYB_HMF|Histone-like transcription factor (CBF/NF-Y) and archaeal histone|ENSGALT00000046827|m.1211:37-100
ENSGALG00000032687	19.02167177	7.076860711	1.425183697	5.13E-23	5.74E-22	up	yes	21.89098388	17.91682425	17.25720717	7.00869055	7.91283027	6.309061312	5	13345327	13346837	+	PHLDA2	protein_coding	GO:0001890|placenta development; GO:0006915|apoptotic process; GO:0009887|animal organ morphogenesis; GO:0010468|regulation of gene expression; GO:0030334|regulation of cell migration; GO:0060721|regulation of spongiotrophoblast cell proliferation; GO:0070873|regulation of glycogen metabolic process; GO:1903547|regulation of growth hormone activity	GO:0005737|cytoplasm; GO:0016020|membrane	--	--	--	1035	XP_015719408.1	XP_015719408.1 PREDICTED: pleckstrin homology-like domain family A member 2 [Coturnix japonica]	sp|Q53GA4|PHLA2_HUMAN	sp|Q53GA4|PHLA2_HUMAN Pleckstrin homology-like domain family A member 2 OS=Homo sapiens GN=PHLDA2 PE=1 SV=2	9031.ENSGALP00000010391	"pleckstrin homology-like domain, family A, member 2"	_	_	NOG47789	_
ENSGALG00000032746	0.733518685	1.593112764	-1.108435007	3.65E-05	9.57E-05	down	yes	0.492440085	0.688265856	1.019850113	1.910188973	1.357221581	1.511927739	2	136526177	136595461	-	ENPP2	protein_coding	GO:0006796|phosphate-containing compound metabolic process; GO:0006935|chemotaxis; GO:0006955|immune response; GO:0007186|G protein-coupled receptor signaling pathway; GO:0009395|phospholipid catabolic process; GO:0010634|positive regulation of epithelial cell migration; GO:0030334|regulation of cell migration; GO:0034638|phosphatidylcholine catabolic process; GO:0045765|regulation of angiogenesis; GO:0048870|cell motility; GO:0050731|positive regulation of peptidyl-tyrosine phosphorylation; GO:2000394|positive regulation of lamellipodium morphogenesis	GO:0005615|extracellular space; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane	GO:0003676|nucleic acid binding; GO:0004528|phosphodiesterase I activity; GO:0004551|nucleotide diphosphatase activity; GO:0004622|lysophospholipase activity; GO:0005044|scavenger receptor activity; GO:0005509|calcium ion binding; GO:0008134|transcription factor binding; GO:0008270|zinc ion binding; GO:0016787|hydrolase activity; GO:0030247|polysaccharide binding; GO:0047391|alkylglycerophosphoethanolamine phosphodiesterase activity	ko:K01122|ENPP2	ko00565|Ether lipid metabolism	3188	NP_001185591.1	NP_001185591.1 ectonucleotide pyrophosphatase/phosphodiesterase family member 2 [Gallus gallus]	sp|Q13822|ENPP2_HUMAN	sp|Q13822|ENPP2_HUMAN Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 OS=Homo sapiens GN=ENPP2 PE=1 SV=3	9031.ENSGALP00000026451	similar to autotaxin-t	COG1524	KOG2645	_	PF01663.19|Phosphodiest|Type I phosphodiesterase / nucleotide pyrophosphatase|ENSGALT00000080987|m.2457:166-479;PF01033.14|Somatomedin_B|Somatomedin B domain|ENSGALT00000080987|m.2457:58-96;PF01033.14|Somatomedin_B|Somatomedin B domain|ENSGALT00000080987|m.2457:101-140;PF01223.20|Endonuclease_NS|DNA/RNA non-specific endonuclease|ENSGALT00000080987|m.2457:608-840
ENSGALG00000032750	1.335505841	0.316917078	2.041152006	5.73E-25	7.13E-24	up	yes	1.65161446	1.114256134	1.24064693	0.252383538	0.36969729	0.328670404	26	1165982	1185894	+	CELSR2	protein_coding	"GO:0006355|regulation of transcription, DNA-templated; GO:0007156|homophilic cell adhesion via plasma membrane adhesion molecules; GO:0007186|G protein-coupled receptor signaling pathway; GO:0016055|Wnt signaling pathway; GO:0021999|neural plate anterior/posterior regionalization; GO:0022407|regulation of cell-cell adhesion; GO:0048813|dendrite morphogenesis; GO:0060071|Wnt signaling pathway, planar cell polarity pathway"	GO:0005737|cytoplasm; GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0004930|G protein-coupled receptor activity; GO:0005509|calcium ion binding	ko:K04601|CELSR2	--	9188	XP_015154265.2	XP_015154265.2 cadherin EGF LAG seven-pass G-type receptor 2 isoform X1 [Gallus gallus]	sp|Q9HCU4|CELR2_HUMAN	sp|Q9HCU4|CELR2_HUMAN Cadherin EGF LAG seven-pass G-type receptor 2 OS=Homo sapiens GN=CELSR2 PE=1 SV=1	28377.ENSACAP00000010383	"cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)"	_	KOG4289	_	"PF00028.14|Cadherin|Cadherin domain|ENSGALT00000073474|m.7710:2-86;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000073474|m.7710:102-195;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000073474|m.7710:209-300;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000073474|m.7710:316-406;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000073474|m.7710:420-508;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000073474|m.7710:522-610;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000073474|m.7710:625-717;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000073474|m.7710:733-817;PF16489.2|GAIN|GPCR-Autoproteolysis INducing (GAIN) domain|ENSGALT00000073474|m.7710:1859-2123;PF02210.21|Laminin_G_2|Laminin G domain|ENSGALT00000073474|m.7710:1199-1357;PF02210.21|Laminin_G_2|Laminin G domain|ENSGALT00000073474|m.7710:1448-1576;PF00002.21|7tm_2|7 transmembrane receptor (Secretin family)|ENSGALT00000073474|m.7710:2212-2436;PF00054.20|Laminin_G_1|Laminin G domain|ENSGALT00000073474|m.7710:1199-1361;PF00054.20|Laminin_G_1|Laminin G domain|ENSGALT00000073474|m.7710:1448-1575;PF00008.24|EGF|EGF-like domain|ENSGALT00000073474|m.7710:1382-1412;PF00008.24|EGF|EGF-like domain|ENSGALT00000073474|m.7710:1639-1672;PF01825.18|GPS|GPCR proteolysis site, GPS, motif|ENSGALT00000073474|m.7710:2152-2197;PF00053.21|Laminin_EGF|Laminin EGF domain|ENSGALT00000073474|m.7710:1731-1770;PF02793.19|HRM|Hormone receptor domain|ENSGALT00000073474|m.7710:1781-1834"
ENSGALG00000032803	1.388772319	0.523371202	1.390949315	0.000711719	0.001532923	up	yes	1.982358507	1.308120281	0.875838171	0.477222759	0.517450259	0.575440587	5	120674	122219	+	ENSGALG00000032803	protein_coding	GO:0001933|negative regulation of protein phosphorylation; GO:0007186|G protein-coupled receptor signaling pathway; GO:0007250|activation of NF-kappaB-inducing kinase activity; GO:0007283|spermatogenesis; GO:0008284|positive regulation of cell population proliferation; GO:0008584|male gonad development; GO:0014823|response to activity; GO:0021766|hippocampus development; GO:0034698|response to gonadotropin; GO:0042493|response to drug; GO:0045740|positive regulation of DNA replication; GO:0050727|regulation of inflammatory response; GO:0060732|positive regulation of inositol phosphate biosynthetic process; GO:0070528|protein kinase C signaling	GO:0005622|intracellular; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0009986|cell surface	GO:0001595|angiotensin receptor activity; GO:0004930|G protein-coupled receptor activity; GO:0017046|peptide hormone binding; GO:0042277|peptide binding	--	--	1329	XP_001236025.2	XP_001236025.2 proto-oncogene Mas isoform X1 [Gallus gallus]	sp|P30554|MAS_MOUSE	sp|P30554|MAS_MOUSE Proto-oncogene Mas OS=Mus musculus GN=Mas1 PE=1 SV=2	_	_	_	_	_	PF00001.18|7tm_1|7 transmembrane receptor (rhodopsin family)|ENSGALT00000065126|m.1983:65-292
ENSGALG00000032937	0.522125923	1.246492937	-1.239562968	6.37E-05	0.000160859	down	yes	0.304182041	0.644298884	0.617896846	1.411149458	0.982473564	1.345855788	3	91025897	91114765	-	DLGAP2	protein_coding	GO:0007270|neuron-neuron synaptic transmission; GO:0065003|protein-containing complex assembly	GO:0014069|postsynaptic density; GO:0030054|cell junction; GO:0045202|synapse; GO:0045211|postsynaptic membrane	GO:0019904|protein domain specific binding	--	--	3096	XP_025004843.1	XP_025004843.1 disks large-associated protein 2 isoform X6 [Gallus gallus]	sp|Q8BJ42|DLGP2_MOUSE	sp|Q8BJ42|DLGP2_MOUSE Disks large-associated protein 2 OS=Mus musculus GN=Dlgap2 PE=1 SV=2	9031.ENSGALP00000026331	annotation not avaliable	_	KOG3971	_	PF03359.10|GKAP|Guanylate-kinase-associated protein (GKAP) protein|ENSGALT00000056309|m.12883:711-1031
ENSGALG00000032957	20.82714944	67.58220494	-1.69769895	6.70E-111	1.09E-108	down	yes	21.71527819	19.5625845	21.20358563	71.31240059	64.37519279	67.05902145	4	29195831	29198493	+	NOCT	protein_coding	GO:0000290|deadenylation-dependent decapping of nuclear-transcribed mRNA; GO:0006397|mRNA processing; GO:0007623|circadian rhythm; GO:0009991|response to extracellular stimulus; GO:0010629|negative regulation of gene expression; GO:0032496|response to lipopolysaccharide; GO:0032922|circadian regulation of gene expression; GO:0033962|cytoplasmic mRNA processing body assembly; GO:0042752|regulation of circadian rhythm; GO:0045600|positive regulation of fat cell differentiation; GO:0045668|negative regulation of osteoblast differentiation; GO:0045995|regulation of embryonic development; GO:0048255|mRNA stabilization	GO:0000932|P-body; GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0048471|perinuclear region of cytoplasm	GO:0003729|mRNA binding; GO:0004535|poly(A)-specific ribonuclease activity; GO:0046872|metal ion binding	ko:K18764|CCRN4L	--	1963	XP_010707866.1	XP_010707866.1 PREDICTED: nocturnin [Meleagris gallopavo]	sp|Q9ET55|NOCT_RAT	sp|Q9ET55|NOCT_RAT Nocturnin OS=Rattus norvegicus GN=Noct PE=2 SV=2	_	_	_	_	_	PF03372.20|Exo_endo_phos|Endonuclease/Exonuclease/phosphatase family|ENSGALT00000053885|m.19:101-369
ENSGALG00000032958	0.461216393	2.161996661	-2.204560251	2.34E-18	1.99E-17	down	yes	0.362024972	0.482612771	0.539011436	1.813603906	2.381987113	2.290398965	2	49138836	49243786	-	AMPH	protein_coding	--	GO:0005856|cytoskeleton; GO:0008021|synaptic vesicle; GO:0030054|cell junction; GO:0030672|synaptic vesicle membrane; GO:0044306|neuron projection terminus	--	ko:K12562|AMPH	ko04144|Endocytosis; ko04666|Fc gamma R-mediated phagocytosis	3202	NP_001004398.1	NP_001004398.1 amphiphysin [Gallus gallus]	sp|P50478|AMPH_CHICK	sp|P50478|AMPH_CHICK Amphiphysin OS=Gallus gallus GN=AMPH PE=2 SV=1	_	_	_	_	_	PF03114.15|BAR|BAR domain|ENSGALT00000059785|m.702:46-264;PF14604.3|SH3_9|Variant SH3 domain|ENSGALT00000059785|m.702:648-710;PF00018.25|SH3_1|SH3 domain|ENSGALT00000059785|m.702:648-687
ENSGALG00000032974	2.397760383	5.428169776	-1.175429368	1.78E-18	1.52E-17	down	yes	2.423097785	2.626303984	2.143879381	5.151639106	5.565435447	5.567434776	13	14367414	14532703	+	ADAMTS2	protein_coding	GO:0007283|spermatogenesis; GO:0016485|protein processing; GO:0030199|collagen fibril organization; GO:0030324|lung development; GO:0030574|collagen catabolic process; GO:0032964|collagen biosynthetic process; GO:0043588|skin development; GO:0097435|supramolecular fiber organization	GO:0005615|extracellular space; GO:0031012|extracellular matrix	GO:0004222|metalloendopeptidase activity; GO:0008270|zinc ion binding	ko:K08618|ADAMTS2	--	3501	XP_414611.6	XP_414611.6 A disintegrin and metalloproteinase with thrombospondin motifs 2 [Gallus gallus]	sp|P79331|ATS2_BOVIN	sp|P79331|ATS2_BOVIN A disintegrin and metalloproteinase with thrombospondin motifs 2 OS=Bos taurus GN=ADAMTS2 PE=1 SV=1	59729.ENSTGUP00000001149	A disintegrin and metalloproteinase with thrombospondin motifs 2 Precursor (ADAMTS-2)(ADAM-T [...] 	_	KOG3538	_	PF01562.16|Pep_M12B_propep|Reprolysin family propeptide|ENSGALT00000067480|m.8925:32-175;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000067480|m.8925:516-565;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000067480|m.8925:865-906;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000067480|m.8925:927-973;PF05986.11|ADAM_spacer1|ADAM-TS Spacer 1|ENSGALT00000067480|m.8925:673-782;PF01421.16|Reprolysin|Reprolysin (M12B) family zinc metalloprotease|ENSGALT00000067480|m.8925:226-420;PF13688.3|Reprolysin_5|Metallo-peptidase family M12|ENSGALT00000067480|m.8925:221-390;PF13582.3|Reprolysin_3|Metallo-peptidase family M12B Reprolysin-like|ENSGALT00000067480|m.8925:243-369;PF13574.3|Reprolysin_2|Metallo-peptidase family M12B Reprolysin-like|ENSGALT00000067480|m.8925:239-379;PF13583.3|Reprolysin_4|Metallo-peptidase family M12B Reprolysin-like|ENSGALT00000067480|m.8925:222-387
ENSGALG00000032980	0.412745901	0.871175807	-1.05963912	0.001147383	0.002394443	down	yes	0.526009161	0.231402224	0.480826318	0.819694914	1.016398109	0.777434399	23	4578052	4585150	+	DLGAP3	protein_coding	GO:0023052|signaling; GO:0065003|protein-containing complex assembly	GO:0014069|postsynaptic density; GO:0030054|cell junction; GO:0045202|synapse; GO:0045211|postsynaptic membrane	GO:0001540|amyloid-beta binding; GO:0019904|protein domain specific binding	--	--	3506	XP_004947837.1	XP_004947837.1 disks large-associated protein 3 isoform X1 [Gallus gallus]	sp|Q6PFD5|DLGP3_MOUSE	sp|Q6PFD5|DLGP3_MOUSE Disks large-associated protein 3 OS=Mus musculus GN=Dlgap3 PE=1 SV=1	_	_	_	_	_	PF03359.10|GKAP|Guanylate-kinase-associated protein (GKAP) protein|ENSGALT00000062290|m.5643:629-960
ENSGALG00000032997	1.574200327	0.58332374	1.416863366	8.47E-11	4.03E-10	up	yes	1.853995486	1.497256285	1.37134921	0.581147536	0.573846604	0.59497708	2	101038793	101069808	-	EMILIN2	protein_coding	GO:0007155|cell adhesion	GO:0005576|extracellular region; GO:0005581|collagen trimer; GO:0005615|extracellular space; GO:0031012|extracellular matrix	GO:0030023|extracellular matrix constituent conferring elasticity	--	--	3567	XP_015133436.2	XP_015133436.2 EMILIN-2 isoform X1 [Gallus gallus]	sp|Q9BXX0|EMIL2_HUMAN	sp|Q9BXX0|EMIL2_HUMAN EMILIN-2 OS=Homo sapiens GN=EMILIN2 PE=1 SV=3	9031.ENSGALP00000023875	elastin microfibril interfacer 2	_	_	NOG73178	PF07546.10|EMI|EMI domain|ENSGALT00000068452|m.1586:24-94;PF00386.18|C1q|C1q domain|ENSGALT00000068452|m.1586:903-1041
ENSGALG00000033012	1.405811236	3.961019138	-1.487880384	8.56E-09	3.40E-08	down	yes	1.630041426	1.314662568	1.272729714	4.291959905	3.223377131	4.367720379	13	17915699	17926509	-	SPRY4	protein_coding	GO:0007275|multicellular organism development; GO:0043407|negative regulation of MAP kinase activity; GO:0070373|negative regulation of ERK1 and ERK2 cascade; GO:1990830|cellular response to leukemia inhibitory factor	GO:0005737|cytoplasm; GO:0032587|ruffle membrane	--	ko:K17385|SPRY4	--	1293	NP_001073203.1	NP_001073203.1 protein sprouty homolog 4 [Gallus gallus]	sp|A2VDU1|SPY4_BOVIN	sp|A2VDU1|SPY4_BOVIN Protein sprouty homolog 4 OS=Bos taurus GN=SPRY4 PE=2 SV=1	9031.ENSGALP00000011856	Sprouty-like protein 4 	_	_	NOG68509	PF05210.10|Sprouty|Sprouty protein (Spry)|ENSGALT00000075192|m.9105:296-405
ENSGALG00000033025	15.87890014	37.06897728	-1.222582189	3.48E-17	2.72E-16	down	yes	18.86755156	12.87771743	15.89143144	40.59135137	31.91087057	38.7047099	12	16797267	16828199	-	RYBP	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006351|transcription, DNA-templated; GO:0006915|apoptotic process; GO:0007275|multicellular organism development; GO:0032435|negative regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0035518|histone H2A monoubiquitination; GO:0043065|positive regulation of apoptotic process; GO:0045893|positive regulation of transcription, DNA-templated"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm	GO:0003677|DNA binding; GO:0003714|transcription corepressor activity; GO:0046872|metal ion binding	ko:K11469|RYBP	--	687	XP_005522035.1	XP_005522035.1 PREDICTED: RING1 and YY1-binding protein isoform X2 [Pseudopodoces humilis]	sp|Q8N488|RYBP_HUMAN	sp|Q8N488|RYBP_HUMAN RING1 and YY1-binding protein OS=Homo sapiens GN=RYBP PE=1 SV=2	9258.ENSOANP00000018545	RING1 and YY1 binding protein	_	KOG4477	_	PF00641.15|zf-RanBP|Zn-finger in Ran binding protein and others|ENSGALT00000049841|m.8040:22-45
ENSGALG00000033091	0.499200833	1.41187391	-1.481486849	1.65E-05	4.51E-05	down	yes	0.450853813	0.34493886	0.701809827	1.327209221	1.938163426	0.970249083	2	124950602	125056942	-	RUNX1T1	protein_coding	"GO:0006091|generation of precursor metabolites and energy; GO:0006351|transcription, DNA-templated; GO:0045599|negative regulation of fat cell differentiation; GO:0045892|negative regulation of transcription, DNA-templated"	GO:0005654|nucleoplasm; GO:0016363|nuclear matrix	GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity; GO:0003714|transcription corepressor activity; GO:0046872|metal ion binding	"ko:K10053|RUNX1T1,CBFA2T1"	ko05200|Pathways in cancer; ko05202|Transcriptional misregulation in cancer; ko05221|Acute myeloid leukemia	2539	NP_990075.2	NP_990075.2 protein CBFA2T1 isoform 1 [Gallus gallus]	sp|Q06455|MTG8_HUMAN	sp|Q06455|MTG8_HUMAN Protein CBFA2T1 OS=Homo sapiens GN=RUNX1T1 PE=1 SV=2	9031.ENSGALP00000025624	"runt-related transcription factor 1; translocated to, 1 (cyclin D-related) "	_	_	NOG79810	PF08788.8|NHR2|NHR2 domain like|ENSGALT00000050192|m.2112:337-403;PF07531.11|TAFH|NHR1 homology to TAF|ENSGALT00000050192|m.2112:123-211;PF01753.15|zf-MYND|MYND finger|ENSGALT00000050192|m.2112:515-551
ENSGALG00000033110	21.95139848	10.22821429	1.101005819	8.79E-36	1.81E-34	up	yes	21.97519649	21.28987212	22.58912684	10.23489353	9.726230844	10.72351849	10	3153960	3157345	+	SNX33	protein_coding	GO:0000281|mitotic cytokinesis; GO:0006886|intracellular protein transport; GO:0006897|endocytosis; GO:0007032|endosome organization; GO:0016197|endosomal transport; GO:0017038|protein import; GO:0036089|cleavage furrow formation; GO:0044351|macropinocytosis; GO:0045806|negative regulation of endocytosis; GO:0051044|positive regulation of membrane protein ectodomain proteolysis; GO:0097320|plasma membrane tubulation; GO:2000009|negative regulation of protein localization to cell surface; GO:2000010|positive regulation of protein localization to cell surface	GO:0005829|cytosol; GO:0016020|membrane; GO:0019898|extrinsic component of membrane; GO:0030659|cytoplasmic vesicle membrane; GO:0031410|cytoplasmic vesicle	GO:0035091|phosphatidylinositol binding; GO:0042802|identical protein binding	ko:K17923|SNX9_18_33	--	2134	XP_015134518.1	XP_015134518.1 sorting nexin-33 [Gallus gallus]	sp|Q8WV41|SNX33_HUMAN	sp|Q8WV41|SNX33_HUMAN Sorting nexin-33 OS=Homo sapiens GN=SNX33 PE=1 SV=1	59729.ENSTGUP00000003827	Sorting nexin-33 (SH3 and PX domain-containing protein 3) [Taeniopygia guttata]	COG5391	KOG2528	_	PF10456.6|BAR_3_WASP_bdg|WASP-binding domain of Sorting nexin protein|ENSGALT00000057059|m.5265:317-552;PF00787.21|PX|PX domain|ENSGALT00000057059|m.5265:211-314;PF14604.3|SH3_9|Variant SH3 domain|ENSGALT00000057059|m.5265:7-57;PF07653.14|SH3_2|Variant SH3 domain|ENSGALT00000057059|m.5265:4-58;PF00018.25|SH3_1|SH3 domain|ENSGALT00000057059|m.5265:6-53
ENSGALG00000033126	73.91784894	34.94952052	1.080432538	9.00E-68	5.52E-66	up	yes	69.61235497	77.59040822	74.55078363	34.17228231	35.41254037	35.26373889	15	1582715	1593688	+	DGCR8	protein_coding	GO:0031053|primary miRNA processing; GO:0072091|regulation of stem cell proliferation	GO:0005634|nucleus; GO:0005730|nucleolus; GO:0005737|cytoplasm; GO:0014069|postsynaptic density; GO:0070877|microprocessor complex	GO:0003725|double-stranded RNA binding; GO:0004525|ribonuclease III activity; GO:0020037|heme binding; GO:0042803|protein homodimerization activity; GO:0046872|metal ion binding; GO:0070878|primary miRNA binding	ko:K18419|DCGR8	--	2980	XP_021267962.1	XP_021267962.1 microprocessor complex subunit DGCR8 isoform X1 [Numida meleagris]	sp|Q9EQM6|DGCR8_MOUSE	sp|Q9EQM6|DGCR8_MOUSE Microprocessor complex subunit DGCR8 OS=Mus musculus GN=Dgcr8 PE=1 SV=2	9031.ENSGALP00000003222	DiGeorge syndrome critical region gene 8	_	KOG4334	_	PF00035.23|dsrm|Double-stranded RNA binding motif|ENSGALT00000073023|m.10355:516-578;PF00035.23|dsrm|Double-stranded RNA binding motif|ENSGALT00000073023|m.10355:622-686
ENSGALG00000033171	2.260690686	5.178677147	-1.192235575	9.34E-13	5.22E-12	down	yes	1.755672941	2.574521851	2.451877266	5.463967514	4.992795091	5.079268836	2	43102691	43113228	-	TGM4	protein_coding	GO:0018149|peptide cross-linking	GO:0005737|cytoplasm; GO:0005794|Golgi apparatus; GO:0031012|extracellular matrix; GO:0070062|extracellular exosome	GO:0003810|protein-glutamine gamma-glutamyltransferase activity; GO:0046872|metal ion binding	ko:K05621|TGM4	--	2489	XP_025002990.1	XP_025002990.1 protein-glutamine gamma-glutamyltransferase 4 isoform X1 [Gallus gallus]	sp|P49221|TGM4_HUMAN	sp|P49221|TGM4_HUMAN Protein-glutamine gamma-glutamyltransferase 4 OS=Homo sapiens GN=TGM4 PE=1 SV=2	9031.ENSGALP00000019372	transglutaminase 4 (prostate) 	_	_	NOG80379	"PF00927.19|Transglut_C|Transglutaminase family, C-terminal ig like domain|ENSGALT00000097384|m.549:547-640;PF01841.16|Transglut_core|Transglutaminase-like superfamily|ENSGALT00000097384|m.549:189-283;PF00868.17|Transglut_N|Transglutaminase family|ENSGALT00000097384|m.549:3-54;PF00868.17|Transglut_N|Transglutaminase family|ENSGALT00000097384|m.550:36-108"
ENSGALG00000033178	27.27171798	108.4672882	-1.991386617	1.47E-207	1.37E-204	down	yes	29.24073148	27.10963291	25.46478954	111.1244202	107.0154139	107.2620305	2	11821968	11830930	-	KLF6	protein_coding	"GO:0030183|B cell differentiation; GO:0045893|positive regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II"	GO:0001650|fibrillar center; GO:0005634|nucleus; GO:0005730|nucleolus; GO:0005829|cytosol; GO:0043231|intracellular membrane-bounded organelle	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0046872|metal ion binding"	ko:K09207|KLF6_7	--	4013	NP_001026140.1	NP_001026140.1 Krueppel-like factor 6 [Gallus gallus]	sp|Q99612|KLF6_HUMAN	sp|Q99612|KLF6_HUMAN Krueppel-like factor 6 OS=Homo sapiens GN=KLF6 PE=1 SV=3	9031.ENSGALP00000011416	Kruppel-like factor 6 	COG5048	KOG1721	_	_
ENSGALG00000033198	1.505645969	0.405603348	1.866653619	7.68E-21	7.53E-20	up	yes	1.229518143	1.50247295	1.784946814	0.395454787	0.433414504	0.387940754	10	9286269	9316180	+	MYO5C	protein_coding	--	GO:0016459|myosin complex; GO:0070062|extracellular exosome	GO:0003774|motor activity; GO:0003779|actin binding; GO:0005516|calmodulin binding; GO:0005524|ATP binding	ko:K10357|MYO5	--	5914	XP_015147454.1	XP_015147454.1 unconventional myosin-Vc isoform X1 [Gallus gallus]	sp|Q9NQX4|MYO5C_HUMAN	sp|Q9NQX4|MYO5C_HUMAN Unconventional myosin-Vc OS=Homo sapiens GN=MYO5C PE=1 SV=2	_	_	_	_	_	PF00063.18|Myosin_head|Myosin head (motor domain)|ENSGALT00000058969|m.5483:70-741;PF01843.16|DIL|DIL domain|ENSGALT00000058969|m.5483:1569-1670;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000058969|m.5483:757-776;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000058969|m.5483:809-827;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000058969|m.5483:832-851;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000058969|m.5483:858-876;PF02736.16|Myosin_N|Myosin N-terminal SH3-like domain|ENSGALT00000058969|m.5483:12-48
ENSGALG00000033256	7.232124184	3.149281939	1.196816225	1.12E-37	2.56E-36	up	yes	7.540362546	6.613595809	7.542414197	3.217801795	3.074248895	3.155795126	Z	37074185	37334639	+	PCSK5	protein_coding	GO:0001822|kidney development; GO:0002001|renin secretion into blood stream; GO:0003279|cardiac septum development; GO:0006465|signal peptide processing; GO:0007267|cell-cell signaling; GO:0007368|determination of left/right symmetry; GO:0007507|heart development; GO:0007566|embryo implantation; GO:0009952|anterior/posterior pattern specification; GO:0016485|protein processing; GO:0016486|peptide hormone processing; GO:0019058|viral life cycle; GO:0030323|respiratory tube development; GO:0032455|nerve growth factor processing; GO:0035108|limb morphogenesis; GO:0042089|cytokine biosynthetic process; GO:0043043|peptide biosynthetic process; GO:0048566|embryonic digestive tract development; GO:0048706|embryonic skeletal system development; GO:0051004|regulation of lipoprotein lipase activity; GO:0060976|coronary vasculature development	GO:0005576|extracellular region; GO:0005615|extracellular space; GO:0005794|Golgi apparatus; GO:0005796|Golgi lumen; GO:0016021|integral component of membrane; GO:0030141|secretory granule	GO:0004175|endopeptidase activity; GO:0004252|serine-type endopeptidase activity; GO:0008233|peptidase activity; GO:0042277|peptide binding	ko:K08654|PCSK5	--	6222	XP_015135840.1	XP_015135840.1 proprotein convertase subtilisin/kexin type 5 isoform X1 [Gallus gallus]	sp|Q92824|PCSK5_HUMAN	sp|Q92824|PCSK5_HUMAN Proprotein convertase subtilisin/kexin type 5 OS=Homo sapiens GN=PCSK5 PE=1 SV=4	9031.ENSGALP00000037337	Proprotein convertase PC6 Fragment 	COG1404;COG4935	KOG3525	_	PF00082.19|Peptidase_S8|Subtilase family|ENSGALT00000024476|m.11275:164-447;PF14843.3|GF_recep_IV|Growth factor receptor domain IV|ENSGALT00000024476|m.11275:638-751;PF01483.17|P_proprotein|Proprotein convertase P-domain|ENSGALT00000024476|m.11275:507-596;PF16470.2|S8_pro-domain|Peptidase S8 pro-domain|ENSGALT00000024476|m.11275:40-116
ENSGALG00000033271	0.332612122	0.689938454	-1.030651875	0.019539952	0.032552218	down	yes	0.333638737	0.192204738	0.471992891	0.71712918	0.829418235	0.523267948	33	7260322	7265353	-	PFKM	protein_coding	GO:0005980|glycogen catabolic process; GO:0006002|fructose 6-phosphate metabolic process; GO:0032024|positive regulation of insulin secretion; GO:0042593|glucose homeostasis; GO:0046716|muscle cell cellular homeostasis; GO:0051259|protein complex oligomerization; GO:0061621|canonical glycolysis; GO:0093001|glycolysis from storage polysaccharide through glucose-1-phosphate	GO:0005945|6-phosphofructokinase complex; GO:0016324|apical plasma membrane; GO:0070062|extracellular exosome; GO:0097228|sperm principal piece	GO:0003872|6-phosphofructokinase activity; GO:0005524|ATP binding; GO:0008022|protein C-terminus binding; GO:0019900|kinase binding; GO:0042803|protein homodimerization activity; GO:0046872|metal ion binding; GO:0070061|fructose binding	"ko:K00850|pfkA,PFK"	ko00010|Glycolysis / Gluconeogenesis; ko00030|Pentose phosphate pathway; ko00051|Fructose and mannose metabolism; ko00052|Galactose metabolism; ko00680|Methane metabolism; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko01120|Microbial metabolism in diverse environments; ko01130|Biosynthesis of antibiotics; ko01200|Carbon metabolism; ko01230|Biosynthesis of amino acids; ko03018|RNA degradation; ko04152|AMPK signaling pathway; ko05230|Central carbon metabolism in cancer	2211	NP_989554.3	"NP_989554.3 ATP-dependent 6-phosphofructokinase, muscle type [Gallus gallus]"	sp|Q0IIG5|PFKAM_BOVIN	"sp|Q0IIG5|PFKAM_BOVIN ATP-dependent 6-phosphofructokinase, muscle type OS=Bos taurus GN=PFKM PE=2 SV=1"	_	_	_	_	_	PF00365.17|PFK|Phosphofructokinase|ENSGALT00000073033|m.15726:216-305;PF00365.17|PFK|Phosphofructokinase|ENSGALT00000073033|m.15726:384-549;PF00365.17|PFK|Phosphofructokinase|ENSGALT00000073033|m.15726:543-642;PF00365.17|PFK|Phosphofructokinase|ENSGALT00000073033|m.15727:2-149
ENSGALG00000033303	0.960880497	0.301304494	1.640967327	3.87E-06	1.15E-05	up	yes	0.761187483	0.945675076	1.175778931	0.222692783	0.342858932	0.338361765	12	2905813	2909869	-	ENSGALG00000033303	protein_coding	GO:0006508|proteolysis; GO:0050435|amyloid-beta metabolic process	GO:0005737|cytoplasm; GO:0070062|extracellular exosome	GO:0003723|RNA binding; GO:0004252|serine-type endopeptidase activity; GO:0008242|omega peptidase activity; GO:0042802|identical protein binding	ko:K01303|APEH	--	2492	XP_015148377.1	XP_015148377.1 acylamino-acid-releasing enzyme isoform X2 [Gallus gallus]	sp|P13676|ACPH_RAT	sp|P13676|ACPH_RAT Acylamino-acid-releasing enzyme OS=Rattus norvegicus GN=Apeh PE=1 SV=1	59729.ENSTGUP00000005278	Acylamino-acid-releasing enzyme (AARE)(EC 3.4.19.1)(Acyl-peptide hydrolase)(APH)(Acylaminoac [...] 	COG1506	KOG2100	_	PF00326.18|Peptidase_S9|Prolyl oligopeptidase family|ENSGALT00000065209|m.7263:563-769;PF00561.17|Abhydrolase_1|alpha/beta hydrolase fold|ENSGALT00000065209|m.7263:539-668
ENSGALG00000033405	3.149893888	1.546002023	1.022032176	1.38E-07	4.88E-07	up	yes	3.22211696	3.213639017	3.013925687	1.755608169	1.480477985	1.401919916	13	10862418	10871777	-	DBN1	protein_coding	GO:0007015|actin filament organization; GO:0007399|nervous system development; GO:0030154|cell differentiation	GO:0005938|cell cortex; GO:0030054|cell junction; GO:0030426|growth cone	GO:0003779|actin binding	--	--	2086	NP_990830.1	NP_990830.1 drebrin [Gallus gallus]	sp|P18302|DREB_CHICK	sp|P18302|DREB_CHICK Drebrin OS=Gallus gallus GN=DBN1 PE=2 SV=4	_	_	_	_	_	PF00241.17|Cofilin_ADF|Cofilin/tropomyosin-type actin-binding protein|ENSGALT00000078180|m.8658:30-145
ENSGALG00000033461	6.985056799	2.958155711	1.236768993	2.51E-08	9.50E-08	up	yes	6.905849655	7.256175147	6.793145594	2.495354221	3.849540593	2.529572319	7	31212705	31221718	+	ENSGALG00000033461	protein_coding	GO:0007420|brain development; GO:0035498|carnosine metabolic process	GO:0043005|neuron projection	GO:0030735|carnosine N-methyltransferase activity; GO:0046539|histamine N-methyltransferase activity	--	--	969	NP_001305361.1	NP_001305361.1 carnosine N-methyltransferase 2 [Gallus gallus]	sp|U3NEE3|HNMTL_CHICK	sp|U3NEE3|HNMTL_CHICK Carnosine N-methyltransferase 2 OS=Gallus gallus PE=1 SV=1	59729.ENSTGUP00000012192	Histamine N-methyltransferase (HMT)(EC 2.1.1.8) [Taeniopygia guttata]	_	_	NOG39680	PF13489.3|Methyltransf_23|Methyltransferase domain|ENSGALT00000062046|m.6689:78-245
ENSGALG00000033522	1.079078262	0.504353926	1.08227431	0.000422507	0.000942433	up	yes	0.878664963	1.140617946	1.217951878	0.595998455	0.279146398	0.637916924	27	7896286	7900911	+	ENSGALG00000033522	protein_coding	GO:0002523|leukocyte migration involved in inflammatory response; GO:0002675|positive regulation of acute inflammatory response; GO:0002687|positive regulation of leukocyte migration; GO:0007155|cell adhesion; GO:0007568|aging; GO:0008217|regulation of blood pressure; GO:0009308|amine metabolic process; GO:0010828|positive regulation of glucose transmembrane transport; GO:0035902|response to immobilization stress; GO:0042755|eating behavior; GO:0046677|response to antibiotic; GO:1902283|negative regulation of primary amine oxidase activity	GO:0005615|extracellular space; GO:0005737|cytoplasm; GO:0005769|early endosome; GO:0005783|endoplasmic reticulum; GO:0005794|Golgi apparatus; GO:0005886|plasma membrane; GO:0005902|microvillus; GO:0009986|cell surface; GO:0016021|integral component of membrane; GO:0043231|intracellular membrane-bounded organelle	GO:0005507|copper ion binding; GO:0005509|calcium ion binding; GO:0008131|primary amine oxidase activity; GO:0042803|protein homodimerization activity; GO:0046982|protein heterodimerization activity; GO:0048038|quinone binding; GO:0052593|tryptamine:oxygen oxidoreductase (deaminating) activity; GO:0052594|aminoacetone:oxygen oxidoreductase(deaminating) activity; GO:0052595|aliphatic-amine oxidase activity; GO:0052596|phenethylamine:oxygen oxidoreductase (deaminating) activity	"ko:K00276|AOC3,AOC2,tynA"	"ko00260|Glycine, serine and threonine metabolism; ko00350|Tyrosine metabolism; ko00360|Phenylalanine metabolism; ko00410|beta-Alanine metabolism; ko00950|Isoquinoline alkaloid biosynthesis; ko00960|Tropane, piperidine and pyridine alkaloid biosynthesis; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites"	3658	XP_004948681.1	XP_004948681.1 membrane primary amine oxidase isoform X1 [Gallus gallus]	sp|O08590|AOC3_RAT	sp|O08590|AOC3_RAT Membrane primary amine oxidase OS=Rattus norvegicus GN=Aoc3 PE=1 SV=4	_	_	_	_	_	"PF01179.17|Cu_amine_oxid|Copper amine oxidase, enzyme domain|ENSGALT00000056820|m.9488:306-710;PF02728.13|Cu_amine_oxidN3|Copper amine oxidase, N3 domain|ENSGALT00000056820|m.9488:161-257;PF02727.13|Cu_amine_oxidN2|Copper amine oxidase, N2 domain|ENSGALT00000056820|m.9488:75-143"
ENSGALG00000033541	3.866877563	8.161039245	-1.075624408	9.83E-27	1.34E-25	down	yes	4.035658415	3.67892973	3.886044543	7.788224584	8.160415097	8.534478055	1	124929946	125232394	-	FRMPD4	protein_coding	GO:0051835|positive regulation of synapse structural plasticity	GO:0005856|cytoskeleton; GO:0032991|protein-containing complex; GO:0043197|dendritic spine	"GO:0005546|phosphatidylinositol-4,5-bisphosphate binding"	--	--	4400	XP_416838.4	XP_416838.4 FERM and PDZ domain-containing protein 4 isoform X3 [Gallus gallus]	sp|Q14CM0|FRPD4_HUMAN	sp|Q14CM0|FRPD4_HUMAN FERM and PDZ domain-containing protein 4 OS=Homo sapiens GN=FRMPD4 PE=1 SV=1	9031.ENSGALP00000026733	FERM and PDZ domain containing 4	_	KOG3552	_	PF00373.15|FERM_M|FERM central domain|ENSGALT00000049598|m.3501:299-424;PF00595.21|PDZ|PDZ domain (Also known as DHR or GLGF)|ENSGALT00000049598|m.3501:86-151
ENSGALG00000033568	94.11545032	43.36402287	1.117753605	2.79E-61	1.44E-59	up	yes	88.67983119	98.96838747	94.69813229	45.56842389	43.73152018	40.79212456	2	118027530	118031704	+	TMEM70	protein_coding	GO:0033615|mitochondrial proton-transporting ATP synthase complex assembly	GO:0005743|mitochondrial inner membrane; GO:0032592|integral component of mitochondrial membrane	--	ko:K17966|TMEM70	--	2243	NP_001012866.1	"NP_001012866.1 transmembrane protein 70, mitochondrial precursor [Gallus gallus]"	sp|Q5ZLJ4|TMM70_CHICK	"sp|Q5ZLJ4|TMM70_CHICK Transmembrane protein 70, mitochondrial OS=Gallus gallus GN=TMEM70 PE=2 SV=1"	9031.ENSGALP00000030240	"Transmembrane protein 70, mitochondrial Precursor ; Involved in biogenesis of mitochondrial  [...] "	_	KOG4478	_	"PF06979.9|TMEM70|Assembly, mitochondrial proton-transport ATP synth complex|ENSGALT00000068732|m.1946:130-261"
ENSGALG00000033589	0.150083613	0.447731586	-1.515676214	0.007154691	0.01300393	down	yes	0.085157316	0.202921608	0.162171916	0.38438124	0.673588142	0.285225376	1	53021721	53223751	+	SYN3	protein_coding	"GO:0007269|neurotransmitter secretion; GO:0032228|regulation of synaptic transmission, GABAergic"	GO:0008021|synaptic vesicle; GO:0014069|postsynaptic density; GO:0030054|cell junction; GO:0030672|synaptic vesicle membrane	GO:0003824|catalytic activity; GO:0005524|ATP binding	ko:K19941|SYN	--	2475	XP_003640437.1	XP_003640437.1 synapsin-3 [Gallus gallus]	sp|O14994|SYN3_HUMAN	sp|O14994|SYN3_HUMAN Synapsin-3 OS=Homo sapiens GN=SYN3 PE=1 SV=2	_	_	_	_	_	"PF02750.11|Synapsin_C|Synapsin, ATP binding domain|ENSGALT00000063535|m.1507:194-396;PF02078.13|Synapsin|Synapsin, N-terminal domain|ENSGALT00000063535|m.1507:92-190;PF10581.6|Synapsin_N|Synapsin N-terminal|ENSGALT00000063535|m.1507:1-30"
ENSGALG00000033622	89.00395644	12.10003273	2.877828789	2.07E-106	3.02E-104	up	yes	98.65800156	92.865046	75.48882174	13.97327332	11.29149683	11.03532804	2	148900799	148901276	-	ENSGALG00000033622	protein_coding	--	GO:0005882|intermediate filament	GO:0005200|structural constituent of cytoskeleton	--	--	478	XP_025003985.1	XP_025003985.1 feather keratin 1-like isoform X2 [Gallus gallus]	sp|P02451|KRFT_LARNO	sp|P02451|KRFT_LARNO Feather keratin OS=Larus novaehollandiae PE=1 SV=1	9031.ENSGALP00000023460	annotation not avaliable	_	_	NOG231326	PF02422.13|Keratin|Keratin|ENSGALT00000053032|m.2677:7-95
ENSGALG00000033631	12.1235435	53.64971976	-2.144838581	4.81E-103	6.32E-101	down	yes	12.34162595	11.29357698	12.73542757	62.00502991	51.10932203	47.83480734	2	139734098	139738744	+	MYC	protein_coding	--	GO:0042025|host cell nucleus	GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity; GO:0046983|protein dimerization activity	ko:K04377|MYC	ko04010|MAPK signaling pathway; ko04012|ErbB signaling pathway; ko04110|Cell cycle; ko04151|PI3K-Akt signaling pathway; ko04310|Wnt signaling pathway; ko04350|TGF-beta signaling pathway; ko04390|Hippo signaling pathway; ko04391|Hippo signaling pathway - fly; ko04550|Signaling pathways regulating pluripotency of stem cells; ko04630|Jak-STAT signaling pathway; ko04919|Thyroid hormone signaling pathway; ko05161|Hepatitis B; ko05166|HTLV-I infection; ko05169|Epstein-Barr virus infection; ko05200|Pathways in cancer; ko05202|Transcriptional misregulation in cancer; ko05205|Proteoglycans in cancer; ko05206|MicroRNAs in cancer; ko05210|Colorectal cancer; ko05213|Endometrial cancer; ko05216|Thyroid cancer; ko05219|Bladder cancer; ko05220|Chronic myeloid leukemia; ko05221|Acute myeloid leukemia; ko05222|Small cell lung cancer; ko05224|Breast cancer; ko05230|Central carbon metabolism in cancer	2199	NP_001026123.1	NP_001026123.1 myc proto-oncogene protein [Gallus gallus]	sp|P10395|MYC_AVIM2	sp|P10395|MYC_AVIM2 Viral myc transforming protein OS=Avian myelocytomatosis virus CMII GN=MYC PE=3 SV=2	9031.ENSGALP00000026259	Myc proto-oncogene protein (c-myc); Participates in the regulation of gene transcription. Bi [...] 	_	_	NOG42590	PF01056.15|Myc_N|Myc amino-terminal region|ENSGALT00000080250|m.2526:1-322;PF02344.12|Myc-LZ|Myc leucine zipper domain|ENSGALT00000080250|m.2526:385-415;PF00010.23|HLH|Helix-loop-helix DNA-binding domain|ENSGALT00000080250|m.2526:332-384
ENSGALG00000033635	2.412835665	6.983593799	-1.52933745	0.005971992	0.011016729	down	yes	4.338415492	1.704069646	1.196021856	6.414870588	7.181963553	7.353947256	8	10713267	10722126	+	PTGS2	protein_coding	GO:0001516|prostaglandin biosynthetic process; GO:0006954|inflammatory response; GO:0006979|response to oxidative stress; GO:0008217|regulation of blood pressure; GO:0019371|cyclooxygenase pathway; GO:0031394|positive regulation of prostaglandin biosynthetic process; GO:0031622|positive regulation of fever generation; GO:0033138|positive regulation of peptidyl-serine phosphorylation; GO:0042127|regulation of cell population proliferation; GO:0043154|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0071456|cellular response to hypoxia; GO:0071471|cellular response to non-ionic osmotic stress; GO:0071498|cellular response to fluid shear stress; GO:0090336|positive regulation of brown fat cell differentiation; GO:1902219|negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005789|endoplasmic reticulum membrane; GO:0031090|organelle membrane; GO:0043005|neuron projection	GO:0004601|peroxidase activity; GO:0004666|prostaglandin-endoperoxide synthase activity; GO:0019899|enzyme binding; GO:0020037|heme binding; GO:0042803|protein homodimerization activity; GO:0046872|metal ion binding; GO:0051213|dioxygenase activity	"ko:K11987|PTGS2,COX2"	ko00590|Arachidonic acid metabolism; ko01100|Metabolic pathways; ko04064|NF-kappa B signaling pathway; ko04370|VEGF signaling pathway; ko04657|IL-17 signaling pathway; ko04668|TNF signaling pathway; ko04723|Retrograde endocannabinoid signaling; ko04726|Serotonergic synapse; ko04913|Ovarian steroidogenesis; ko04921|Oxytocin signaling pathway; ko04923|Regulation of lipolysis in adipocytes; ko05140|Leishmaniasis; ko05200|Pathways in cancer; ko05204|Chemical carcinogenesis; ko05206|MicroRNAs in cancer; ko05222|Small cell lung cancer	4665	NP_001161191.1	NP_001161191.1 prostaglandin G/H synthase 2 isoform 1 precursor [Gallus gallus]	sp|P27607|PGH2_CHICK	sp|P27607|PGH2_CHICK Prostaglandin G/H synthase 2 OS=Gallus gallus GN=PTGS2 PE=2 SV=1	9031.ENSGALP00000008111	Prostaglandin G/H synthase 2 Precursor (EC 1.14.99.1)(Cyclooxygenase-2)(COX-2)(Prostaglandin [...] 	_	KOG2408	_	PF03098.12|An_peroxidase|Animal haem peroxidase|ENSGALT00000047966|m.7332:211-559;PF00008.24|EGF|EGF-like domain|ENSGALT00000047966|m.7332:22-53
ENSGALG00000033653	1.033239733	0.471451762	1.115607558	0.000192342	0.000451889	up	yes	1.081098735	1.195091201	0.823529262	0.387884715	0.611754856	0.414715716	25	3540966	3548428	+	ENSGALG00000033653	protein_coding	GO:0002027|regulation of heart rate; GO:0003254|regulation of membrane depolarization; GO:0006812|cation transport; GO:0006936|muscle contraction; GO:0008015|blood circulation; GO:0035725|sodium ion transmembrane transport; GO:0042391|regulation of membrane potential; GO:0055117|regulation of cardiac muscle contraction; GO:0071320|cellular response to cAMP; GO:0071321|cellular response to cGMP; GO:0071805|potassium ion transmembrane transport; GO:0086012|membrane depolarization during cardiac muscle cell action potential; GO:0086015|SA node cell action potential; GO:0086046|membrane depolarization during SA node cell action potential; GO:0086091|regulation of heart rate by cardiac conduction; GO:0098719|sodium ion import across plasma membrane; GO:0098909|regulation of cardiac muscle cell action potential involved in regulation of contraction; GO:1990573|potassium ion import across plasma membrane	GO:0005886|plasma membrane; GO:0031226|intrinsic component of plasma membrane; GO:0048471|perinuclear region of cytoplasm; GO:0098855|HCN channel complex	GO:0005222|intracellular cAMP-activated cation channel activity; GO:0005248|voltage-gated sodium channel activity; GO:0005249|voltage-gated potassium channel activity; GO:0030552|cAMP binding; GO:0042802|identical protein binding; GO:0086041|voltage-gated potassium channel activity involved in SA node cell action potential depolarization	ko:K04956|HCN3	--	2466	XP_015154132.1	XP_015154132.1 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 [Gallus gallus]	sp|Q9Y3Q4|HCN4_HUMAN	sp|Q9Y3Q4|HCN4_HUMAN Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 OS=Homo sapiens GN=HCN4 PE=1 SV=1	8364.ENSXETP00000014338	hyperpolarization activated cyclic nucleotide-gated potassium channel 3	COG0664	KOG0498	_	PF00520.28|Ion_trans|Ion transport protein|ENSGALT00000067932|m.7266:128-389;PF08412.7|Ion_trans_N|Ion transport protein N-terminal|ENSGALT00000067932|m.7266:84-126;PF00027.26|cNMP_binding|Cyclic nucleotide-binding domain|ENSGALT00000067932|m.7266:481-563
ENSGALG00000033683	9.938549877	27.13544931	-1.448152208	4.10E-57	1.83E-55	down	yes	9.844343396	9.713932532	10.2573737	29.50926814	25.17847528	26.7186045	27	6034509	6040276	+	PHOSPHO1	protein_coding	GO:0030500|regulation of bone mineralization; GO:0035630|bone mineralization involved in bone maturation	GO:0031012|extracellular matrix; GO:0065010|extracellular membrane-bounded organelle	GO:0016791|phosphatase activity; GO:0046872|metal ion binding; GO:0052731|phosphocholine phosphatase activity; GO:0052732|phosphoethanolamine phosphatase activity	ko:K06124|PHOSPHO1	ko00564|Glycerophospholipid metabolism; ko01100|Metabolic pathways	2430	XP_015154919.2	XP_015154919.2 phosphoethanolamine/phosphocholine phosphatase isoform X1 [Gallus gallus]	sp|O73884|PHOP1_CHICK	sp|O73884|PHOP1_CHICK Phosphoethanolamine/phosphocholine phosphatase OS=Gallus gallus GN=PHOSPHO1 PE=2 SV=1	9031.ENSGALP00000001955	Phosphoethanolamine/phosphocholine phosphatase (EC 3.1.3.75)(3X11A); Phosphatase that has a  [...] 	_	KOG3120	_	PF06888.9|Put_Phosphatase|Putative Phosphatase|ENSGALT00000048733|m.9018:27-263;PF12710.4|HAD|haloacid dehalogenase-like hydrolase|ENSGALT00000048733|m.9018:30-208
ENSGALG00000033696	2.436435648	5.677890475	-1.217212351	4.47E-14	2.79E-13	down	yes	2.111482623	2.448877413	2.748946908	4.909787701	5.587468853	6.536414872	20	1689083	1801951	-	RALY	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated; GO:0006397|mRNA processing; GO:0008380|RNA splicing; GO:0042632|cholesterol homeostasis; GO:1903506|regulation of nucleic acid-templated transcription"	GO:0005634|nucleus; GO:0071013|catalytic step 2 spliceosome	GO:0003712|transcription coregulator activity; GO:0003723|RNA binding	"ko:K12895|RALY,HNRNPCL2"	--	2728	XP_004947021.1	XP_004947021.1 RNA-binding protein Raly isoform X1 [Gallus gallus]	sp|Q64012|RALY_MOUSE	sp|Q64012|RALY_MOUSE RNA-binding protein Raly OS=Mus musculus GN=Raly PE=1 SV=3	9031.ENSGALP00000039622	"RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))"	_	KOG0118	_	"PF00076.19|RRM_1|RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)|ENSGALT00000094326|m.2849:23-85"
ENSGALG00000033730	1.464736293	3.303673899	-1.167974633	6.86E-10	3.00E-09	down	yes	1.384211121	1.442233131	1.567764628	3.822802972	2.780471966	3.307746759	5	21936956	21959269	+	ENSGALG00000033730	protein_coding	GO:0009058|biosynthetic process	--	GO:0003824|catalytic activity; GO:0030170|pyridoxal phosphate binding	--	--	2631	XP_015142682.1	XP_015142682.1 probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2 isoform X1 [Gallus gallus]	sp|Q5E9H2|1A1L1_BOVIN	sp|Q5E9H2|1A1L1_BOVIN 1-aminocyclopropane-1-carboxylate synthase-like protein 1 OS=Bos taurus GN=ACCS PE=2 SV=1	9031.ENSGALP00000012970	similar to RGD1309314_predicted protein	COG0436	KOG0256	_	PF00155.18|Aminotran_1_2|Aminotransferase class I and II|ENSGALT00000096789|m.2912:426-790;PF13837.3|Myb_DNA-bind_4|Myb/SANT-like DNA-binding domain|ENSGALT00000096789|m.2912:12-99
ENSGALG00000033811	1.235953407	0.522433113	1.226577916	1.46E-06	4.57E-06	up	yes	1.56483396	1.046371908	1.096654352	0.583900583	0.4010382	0.582360555	7	22183985	22193854	+	PTPRN	protein_coding	"GO:0000302|response to reactive oxygen species; GO:0001553|luteinization; GO:0006351|transcription, DNA-templated; GO:0009749|response to glucose; GO:0019221|cytokine-mediated signaling pathway; GO:0019932|second-messenger-mediated signaling; GO:0030073|insulin secretion; GO:0032868|response to insulin; GO:0035773|insulin secretion involved in cellular response to glucose stimulus; GO:0043627|response to estrogen; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0051591|response to cAMP; GO:1904692|positive regulation of type B pancreatic cell proliferation; GO:1990502|dense core granule maturation"	GO:0005634|nucleus; GO:0005768|endosome; GO:0005886|plasma membrane; GO:0016020|membrane; GO:0016021|integral component of membrane; GO:0030054|cell junction; GO:0030141|secretory granule; GO:0030424|axon; GO:0030658|transport vesicle membrane; GO:0043025|neuronal cell body; GO:0043204|perikaryon; GO:0043679|axon terminus; GO:0045202|synapse	GO:0008134|transcription factor binding; GO:0030507|spectrin binding; GO:0044389|ubiquitin-like protein ligase binding; GO:0051020|GTPase binding	ko:K07817|PTPRN	ko04940|Type I diabetes mellitus	4209	XP_015145574.1	XP_015145574.1 receptor-type tyrosine-protein phosphatase-like N isoform X1 [Gallus gallus]	sp|Q63259|PTPRN_RAT	sp|Q63259|PTPRN_RAT Receptor-type tyrosine-protein phosphatase-like N OS=Rattus norvegicus GN=Ptprn PE=1 SV=2	59729.ENSTGUP00000006162	Receptor-type tyrosine-protein phosphatase-like N Precursor (R-PTP-N)(PTP IA-2)(Islet cell a [...] 	COG5599	KOG0793	_	PF00102.24|Y_phosphatase|Protein-tyrosine phosphatase|ENSGALT00000072293|m.6366:701-934;PF11548.5|Receptor_IA-2|Protein-tyrosine phosphatase receptor IA-2|ENSGALT00000072293|m.6366:435-523;PF14948.3|RESP18|RESP18 domain|ENSGALT00000072293|m.6366:52-123
ENSGALG00000033813	11.96132186	27.16023416	-1.182444538	4.44E-39	1.06E-37	down	yes	12.77430763	10.86127769	12.24838025	25.9912593	28.42205616	27.06738703	5	52935364	52938063	+	BTBD6	protein_coding	--	GO:0000932|P-body	--	ko:K10478|BTBD3_6	--	2248	XP_004936479.1	XP_004936479.1 BTB/POZ domain-containing protein 6 isoform X1 [Gallus gallus]	sp|Q2LE78|BTBD6_XENLA	sp|Q2LE78|BTBD6_XENLA BTB/POZ domain-containing protein 6 OS=Xenopus laevis GN=btbd6 PE=1 SV=1	9031.ENSGALP00000019114	annotation not avaliable	_	KOG2075	_	PF08005.9|PHR|PHR domain|ENSGALT00000057576|m.3977:384-529;PF00651.28|BTB|BTB/POZ domain|ENSGALT00000057576|m.3977:122-227;PF07707.12|BACK|BTB And C-terminal Kelch|ENSGALT00000057576|m.3977:238-307
ENSGALG00000033816	0.640274832	2.243044965	-1.792754613	4.44E-06	1.30E-05	down	yes	0.592640061	0.671537412	0.656647023	2.168408358	2.535640946	2.025085589	1	155899968	155900945	+	KCTD12	protein_coding	GO:0008277|regulation of G protein-coupled receptor signaling pathway; GO:0051260|protein homooligomerization	GO:0030054|cell junction; GO:0042734|presynaptic membrane; GO:0043235|receptor complex; GO:0045211|postsynaptic membrane; GO:0070062|extracellular exosome	GO:0003723|RNA binding; GO:0042802|identical protein binding	--	--	978	XP_015132653.2	XP_015132653.2 BTB/POZ domain-containing protein KCTD12 [Gallus gallus]	sp|Q6WVG3|KCD12_MOUSE	sp|Q6WVG3|KCD12_MOUSE BTB/POZ domain-containing protein KCTD12 OS=Mus musculus GN=Kctd12 PE=1 SV=1	_	_	_	_	_	PF02214.19|BTB_2|BTB/POZ domain|ENSGALT00000070720|m.4093:38-127
ENSGALG00000033855	11.85448124	3.846376032	1.621331382	1.37E-55	5.82E-54	up	yes	11.00218597	11.93137821	12.62987954	4.029376833	3.656461693	3.85328957	1	65337341	65349940	+	GOLT1B	protein_coding	GO:0015031|protein transport; GO:0016192|vesicle-mediated transport; GO:0043123|positive regulation of I-kappaB kinase/NF-kappaB signaling	GO:0000139|Golgi membrane; GO:0005783|endoplasmic reticulum; GO:0016021|integral component of membrane	--	--	--	3055	XP_003202556.1	XP_003202556.1 PREDICTED: vesicle transport protein GOT1B [Meleagris gallopavo]	sp|Q2YDE3|GOT1B_BOVIN	sp|Q2YDE3|GOT1B_BOVIN Vesicle transport protein GOT1B OS=Bos taurus GN=GOLT1B PE=2 SV=1	_	_	_	_	_	PF04178.9|Got1|Got1/Sft2-like family|ENSGALT00000060053|m.1974:59-154
ENSGALG00000033883	0.290445395	0.641604848	-1.116894528	0.001774116	0.003592534	down	yes	0.351093879	0.376232647	0.144009659	0.645078557	0.6515567	0.628179287	4	71575850	71827560	-	PCDH7	protein_coding	GO:0002576|platelet degranulation; GO:0007156|homophilic cell adhesion via plasma membrane adhesion molecules	GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0031092|platelet alpha granule membrane	GO:0005509|calcium ion binding	ko:K16498|PCDHD1	--	3846	XP_025005551.1	XP_025005551.1 protocadherin-7 isoform X1 [Gallus gallus]	sp|O60245|PCDH7_HUMAN	sp|O60245|PCDH7_HUMAN Protocadherin-7 OS=Homo sapiens GN=PCDH7 PE=1 SV=2	_	_	_	_	_	PF00028.14|Cadherin|Cadherin domain|ENSGALT00000065137|m.1248:312-404;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000065137|m.1248:429-525;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000065137|m.1248:541-635;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000065137|m.1248:650-743;PF00028.14|Cadherin|Cadherin domain|ENSGALT00000065137|m.1248:769-850;PF08374.8|Protocadherin|Protocadherin|ENSGALT00000065137|m.1248:853-1064;PF08266.9|Cadherin_2|Cadherin-like|ENSGALT00000065137|m.1248:37-117
ENSGALG00000033885	0.309915984	1.295951702	-2.02933656	2.70E-18	2.28E-17	down	yes	0.312053132	0.296091047	0.321603774	1.077117785	1.441061812	1.369675508	19	9665263	9716788	+	RAP1GAP2	protein_coding	GO:0051056|regulation of small GTPase mediated signal transduction	GO:0005737|cytoplasm	GO:0005096|GTPase activator activity	ko:K17708|RAP1GAP2	--	5116	XP_015151302.1	XP_015151302.1 rap1 GTPase-activating protein 2 isoform X2 [Gallus gallus]	sp|Q5ZMV8|RPGP2_CHICK	sp|Q5ZMV8|RPGP2_CHICK Rap1 GTPase-activating protein 2 OS=Gallus gallus GN=RAP1GAP2 PE=2 SV=2	9031.ENSGALP00000009417	Rap1 GTPase-activating protein 2 (Rap1GAP2)(GTPase-activating Rap/Ran-GAP domain-like protei [...] 	_	KOG3686	_	PF02145.12|Rap_GAP|Rap/ran-GAP|ENSGALT00000095391|m.14232:434-613
ENSGALG00000033908	6.121467091	2.007498717	1.603664556	6.54E-15	4.34E-14	up	yes	6.689477399	6.718809095	4.956114779	2.022179569	1.52216277	2.478153812	4	66445833	66452314	-	SLC10A4	protein_coding	GO:0015721|bile acid and bile salt transport; GO:0030534|adult behavior; GO:0042493|response to drug	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0008508|bile acid:sodium symporter activity	ko:K14344|SLC10A4	--	1281	XP_001233594.2	XP_001233594.2 sodium/bile acid cotransporter 4 [Gallus gallus]	sp|Q3UEZ8|NTCP4_MOUSE	sp|Q3UEZ8|NTCP4_MOUSE Sodium/bile acid cotransporter 4 OS=Mus musculus GN=Slc10a4 PE=2 SV=1	59729.ENSTGUP00000008315	Sodium/bile acid cotransporter 4 (Na(+)/bile acid cotransporter 4)(Solute carrier family 10  [...] 	COG0385	KOG2718	_	PF01758.13|SBF|Sodium Bile acid symporter family|ENSGALT00000106946|m.1136:99-272
ENSGALG00000033920	0.560525626	1.799493083	-1.665221999	8.80E-06	2.50E-05	down	yes	0.23950495	0.448768941	0.993302987	1.691677854	1.726069615	1.980731779	17	608979	632013	-	ENSGALG00000033920	protein_coding	--	--	GO:0046872|metal ion binding	--	--	1980	XP_004945810.1	XP_004945810.1 ankyrin repeat and MYND domain-containing protein 1 isoform X3 [Gallus gallus]	sp|Q9P2S6|ANKY1_HUMAN	sp|Q9P2S6|ANKY1_HUMAN Ankyrin repeat and MYND domain-containing protein 1 OS=Homo sapiens GN=ANKMY1 PE=2 SV=2	_	_	_	_	_	PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000082335|m.11583:39-124;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000082335|m.11583:175-241;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000082335|m.11583:93-124;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000082335|m.11583:176-208;PF01753.15|zf-MYND|MYND finger|ENSGALT00000082335|m.11583:394-434;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000082335|m.11584:35-117;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000082335|m.11584:75-128;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000082335|m.11584:90-126;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000082335|m.11584:89-118
ENSGALG00000033966	1.040510501	2.72265641	-1.379213492	2.81E-23	3.19E-22	down	yes	0.81883514	1.089044409	1.213651954	2.695626255	2.784074047	2.688268928	1	193461898	193803700	+	TENM4	protein_coding	GO:0000902|cell morphogenesis; GO:0001702|gastrulation with mouth forming second; GO:0007157|heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; GO:0007165|signal transduction; GO:0031641|regulation of myelination; GO:0031643|positive regulation of myelination; GO:0032289|central nervous system myelin formation; GO:0048666|neuron development; GO:0048714|positive regulation of oligodendrocyte differentiation; GO:0060038|cardiac muscle cell proliferation; GO:0060912|cardiac cell fate specification; GO:0097264|self proteolysis; GO:2000543|positive regulation of gastrulation	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0043005|neuron projection	GO:0042803|protein homodimerization activity; GO:0046982|protein heterodimerization activity; GO:0050839|cell adhesion molecule binding	--	--	8301	NP_001341660.1	NP_001341660.1 teneurin-4 [Gallus gallus]	sp|Q6N022|TEN4_HUMAN	sp|Q6N022|TEN4_HUMAN Teneurin-4 OS=Homo sapiens GN=TENM4 PE=1 SV=2	10141.ENSCPOP00000002664	"odz, odd Oz/ten-m homolog 4 (Drosophila)"	_	KOG4659	_	PF06484.9|Ten_N|Teneurin Intracellular Region|ENSGALT00000070488|m.4781:11-165;PF06484.9|Ten_N|Teneurin Intracellular Region|ENSGALT00000070488|m.4781:165-337;PF15636.3|Tox-GHH|GHH signature containing HNH/Endo VII superfamily nuclease toxin|ENSGALT00000070488|m.4781:2682-2759;PF12661.4|hEGF|Human growth factor-like EGF|ENSGALT00000070488|m.4781:771-783
ENSGALG00000033989	10.43601779	4.343297399	1.262772579	1.37E-41	3.72E-40	up	yes	10.15906501	10.98080921	10.16817915	3.955542268	4.467733732	4.606616196	22	1592652	1603593	-	SLC39A14	protein_coding	GO:0071577|zinc ion transmembrane transport	GO:0005737|cytoplasm; GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0030027|lamellipodium	GO:0005384|manganese ion transmembrane transporter activity	"ko:K14720|SLC39A14,ZIP14"	ko04216|Ferroptosis	4370	XP_024998710.1	XP_024998710.1 zinc transporter ZIP14 isoform X2 [Gallus gallus]	sp|Q5RAB7|S39AE_PONAB	sp|Q5RAB7|S39AE_PONAB Zinc transporter ZIP14 OS=Pongo abelii GN=SLC39A14 PE=2 SV=2	_	_	_	_	_	PF02535.19|Zip|ZIP Zinc transporter|ENSGALT00000080515|m.4574:285-614
ENSGALG00000034030	12.47756553	26.33911169	-1.077262077	1.62E-41	4.38E-40	down	yes	12.85493059	12.31052574	12.26724026	25.27746463	26.5377701	27.20210035	3	57964558	58039567	-	L3MBTL3	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0016569|covalent chromatin modification; GO:0030225|macrophage differentiation; GO:0030851|granulocyte differentiation; GO:0043249|erythrocyte maturation"	GO:0005634|nucleus; GO:0005730|nucleolus	GO:0003700|DNA-binding transcription factor activity; GO:0008270|zinc ion binding	--	--	2611	XP_419742.5	XP_419742.5 lethal(3)malignant brain tumor-like protein 3 isoform X2 [Gallus gallus]	sp|Q96JM7|LMBL3_HUMAN	sp|Q96JM7|LMBL3_HUMAN Lethal(3)malignant brain tumor-like protein 3 OS=Homo sapiens GN=L3MBTL3 PE=1 SV=2	_	_	_	_	_	"PF02820.15|MBT|mbt repeat|ENSGALT00000065371|m.12213:245-313;PF02820.15|MBT|mbt repeat|ENSGALT00000065371|m.12213:352-419;PF02820.15|MBT|mbt repeat|ENSGALT00000065371|m.12213:456-520;PF00536.27|SAM_1|SAM domain (Sterile alpha motif)|ENSGALT00000065371|m.12213:739-803;PF01530.15|zf-C2HC|Zinc finger, C2HC type|ENSGALT00000065371|m.12213:534-563;PF07647.14|SAM_2|SAM domain (Sterile alpha motif)|ENSGALT00000065371|m.12213:739-800"
ENSGALG00000034065	10.94643955	24.474721	-1.160102706	1.36E-52	5.40E-51	down	yes	10.73337	11.09520852	11.01074013	25.28157216	24.18804595	23.9545449	4	83916252	83928157	+	ENSGALG00000034065	protein_coding	GO:0006369|termination of RNA polymerase II transcription; GO:0006398|mRNA 3'-end processing by stem-loop binding and cleavage; GO:0006406|mRNA export from nucleus; GO:0008334|histone mRNA metabolic process; GO:0033260|nuclear DNA replication; GO:0044770|cell cycle phase transition; GO:0051028|mRNA transport	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005730|nucleolus; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0071204|histone pre-mRNA 3'end processing complex; GO:1990904|ribonucleoprotein complex	GO:0003723|RNA binding; GO:0003729|mRNA binding; GO:0071207|histone pre-mRNA stem-loop binding; GO:0071208|histone pre-mRNA DCP binding	ko:K18710|SLBP	--	3186	XP_015141480.2	XP_015141480.2 uncharacterized protein LOC422901 [Gallus gallus]	sp|Q14493|SLBP_HUMAN	sp|Q14493|SLBP_HUMAN Histone RNA hairpin-binding protein OS=Homo sapiens GN=SLBP PE=1 SV=1	9031.ENSGALP00000031392	similar to Slbp protein	_	KOG3934	_	PF15247.3|SLBP_RNA_bind|Histone RNA hairpin-binding protein RNA-binding domain|ENSGALT00000055193|m.1512:119-187
ENSGALG00000034069	0.650735127	1.687975139	-1.361671385	7.20E-06	2.07E-05	down	yes	0.446136672	0.826377589	0.67969112	1.863613091	1.810887239	1.389425087	33	7312520	7316977	-	TMEM106C	protein_coding	--	GO:0005789|endoplasmic reticulum membrane; GO:0016020|membrane; GO:0016021|integral component of membrane	--	--	--	2241	XP_015128097.1	XP_015128097.1 transmembrane protein 106C [Gallus gallus]	sp|Q9BVX2|T106C_HUMAN	sp|Q9BVX2|T106C_HUMAN Transmembrane protein 106C OS=Homo sapiens GN=TMEM106C PE=1 SV=1	9031.ENSGALP00000022073	transmembrane protein 106C	_	_	NOG41095	PF07092.9|DUF1356|Protein of unknown function (DUF1356)|ENSGALT00000105176|m.15739:59-177;PF07092.9|DUF1356|Protein of unknown function (DUF1356)|ENSGALT00000105176|m.15741:1-87
ENSGALG00000034077	1.08193368	2.390343799	-1.136355822	8.13E-08	2.92E-07	down	yes	1.099776739	0.979148101	1.166876199	2.39342866	2.190322605	2.587280132	3	29310781	29341097	+	KCNK5	protein_coding	GO:0006813|potassium ion transport; GO:0007588|excretion; GO:0030322|stabilization of membrane potential	GO:0005887|integral component of plasma membrane	GO:0005249|voltage-gated potassium channel activity; GO:0005267|potassium channel activity; GO:0022841|potassium ion leak channel activity	ko:K04916|KCNK5	ko04742|Taste transduction; ko04974|Protein digestion and absorption	2683	XP_419478.2	XP_419478.2 potassium channel subfamily K member 5 isoform X1 [Gallus gallus]	sp|O95279|KCNK5_HUMAN	sp|O95279|KCNK5_HUMAN Potassium channel subfamily K member 5 OS=Homo sapiens GN=KCNK5 PE=1 SV=1	9031.ENSGALP00000016345	"potassium channel, subfamily K, member 5"	_	KOG1418	_	PF07885.13|Ion_trans_2|Ion channel|ENSGALT00000056821|m.11357:261-320;PF07885.13|Ion_trans_2|Ion channel|ENSGALT00000056821|m.11357:355-430
ENSGALG00000034107	0.067390778	1.517038203	-4.302430678	2.63E-20	2.51E-19	down	yes	0	0.11944293	0.082729404	1.307239532	1.775371014	1.468504063	23	3365953	3371497	+	TRIM63	protein_coding	GO:0006936|muscle contraction; GO:0010468|regulation of gene expression; GO:0010614|negative regulation of cardiac muscle hypertrophy; GO:0014732|skeletal muscle atrophy; GO:0014878|response to electrical stimulus involved in regulation of muscle adaptation; GO:0014894|response to denervation involved in regulation of muscle adaptation; GO:0043161|proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0051384|response to glucocorticoid; GO:0070555|response to interleukin-1; GO:0071549|cellular response to dexamethasone stimulus	GO:0000151|ubiquitin ligase complex; GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0030018|Z disc; GO:0031430|M band; GO:0043292|contractile fiber	GO:0004842|ubiquitin-protein transferase activity; GO:0008270|zinc ion binding; GO:0031432|titin binding; GO:0061630|ubiquitin protein ligase activity	"ko:K10655|TRIM63,MURF1"	--	2148	XP_021230879.1	XP_021230879.1 E3 ubiquitin-protein ligase TRIM63 isoform X1 [Numida meleagris]	sp|Q91Z63|TRI63_RAT	sp|Q91Z63|TRI63_RAT E3 ubiquitin-protein ligase TRIM63 OS=Rattus norvegicus GN=Trim63 PE=2 SV=1	_	_	_	_	_	"PF13445.3|zf-RING_UBOX|RING-type zinc-finger|ENSGALT00000103552|m.5451:48-100;PF13923.3|zf-C3HC4_2|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000103552|m.5451:48-78;PF00097.22|zf-C3HC4|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000103552|m.5451:48-102;PF14634.3|zf-RING_5|zinc-RING finger domain|ENSGALT00000103552|m.5451:48-103;PF13639.3|zf-RING_2|Ring finger domain|ENSGALT00000103552|m.5451:48-103;PF13920.3|zf-C3HC4_3|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000103552|m.5451:45-106;PF00643.21|zf-B_box|B-box zinc finger|ENSGALT00000103552|m.5451:143-176"
ENSGALG00000034109	10.93006295	3.392681928	1.684876836	9.69E-52	3.70E-50	up	yes	10.68271836	10.4055993	11.7018712	3.067096883	3.660285223	3.450663679	4	15743145	15884846	-	GRIA3	protein_coding	GO:0006810|transport; GO:0007215|glutamate receptor signaling pathway	GO:0005886|plasma membrane; GO:0030054|cell junction; GO:0030666|endocytic vesicle membrane; GO:0032281|AMPA glutamate receptor complex; GO:0045211|postsynaptic membrane	GO:0001540|amyloid-beta binding; GO:0004971|AMPA glutamate receptor activity; GO:0005231|excitatory extracellular ligand-gated ion channel activity; GO:0005234|extracellularly glutamate-gated ion channel activity	ko:K05199|GRIA3	ko04024|cAMP signaling pathway; ko04080|Neuroactive ligand-receptor interaction; ko04713|Circadian entrainment; ko04723|Retrograde endocannabinoid signaling; ko04724|Glutamatergic synapse; ko04728|Dopaminergic synapse; ko04730|Long-term depression; ko05031|Amphetamine addiction; ko05033|Nicotine addiction; ko05202|Transcriptional misregulation in cancer	2948	NP_990546.2	NP_990546.2 glutamate receptor 3 isoform 2 precursor [Gallus gallus]	sp|P42263|GRIA3_HUMAN	sp|P42263|GRIA3_HUMAN Glutamate receptor 3 OS=Homo sapiens GN=GRIA3 PE=1 SV=2	_	_	_	_	_	"PF00060.23|Lig_chan|Ligand-gated ion channel|ENSGALT00000049874|m.16590:585-867;PF01094.25|ANF_receptor|Receptor family ligand binding region|ENSGALT00000049874|m.16590:79-423;PF10613.6|Lig_chan-Glu_bd|Ligated ion channel L-glutamate- and glycine-binding site|ENSGALT00000049874|m.16590:456-570;PF00497.17|SBP_bac_3|Bacterial extracellular solute-binding proteins, family 3|ENSGALT00000049874|m.16590:479-830"
ENSGALG00000034166	14.08184702	33.34547175	-1.243062728	2.31E-70	1.53E-68	down	yes	14.8847683	13.43761819	13.92315458	33.1228169	34.4788478	32.43475056	11	17808079	17849306	-	ZCCHC14	protein_coding	--	--	GO:0003676|nucleic acid binding; GO:0008270|zinc ion binding; GO:0035091|phosphatidylinositol binding	--	--	4255	XP_015148137.1	XP_015148137.1 zinc finger CCHC domain-containing protein 14 [Gallus gallus]	sp|Q8WYQ9|ZCH14_HUMAN	sp|Q8WYQ9|ZCH14_HUMAN Zinc finger CCHC domain-containing protein 14 OS=Homo sapiens GN=ZCCHC14 PE=1 SV=1	9031.ENSGALP00000009255	similar to M-BDG29	_	KOG3791;KOG4400	_	PF00098.20|zf-CCHC|Zinc knuckle|ENSGALT00000054303|m.6823:1042-1058
ENSGALG00000034213	3.402599973	7.814767699	-1.197176611	9.92E-17	7.47E-16	down	yes	3.625700806	3.473243291	3.108855822	8.840718685	6.405943767	8.197640644	21	5453941	5467117	-	TNFRSF1B	protein_coding	GO:0006954|inflammatory response; GO:0006955|immune response; GO:0007275|multicellular organism development; GO:0032496|response to lipopolysaccharide; GO:0033209|tumor necrosis factor-mediated signaling pathway; GO:0042127|regulation of cell population proliferation; GO:0043066|negative regulation of apoptotic process; GO:0043154|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0097190|apoptotic signaling pathway	GO:0005576|extracellular region; GO:0005615|extracellular space; GO:0005887|integral component of plasma membrane	GO:0005031|tumor necrosis factor-activated receptor activity; GO:0038023|signaling receptor activity	"ko:K05141|TNFRSF1B,TNFR2,CD120b"	ko04060|Cytokine-cytokine receptor interaction; ko04668|TNF signaling pathway; ko04920|Adipocytokine signaling pathway; ko05014|Amyotrophic lateral sclerosis (ALS)	2892	BAC55966.1	BAC55966.1 tumor necrosis factor receptor-II [Gallus gallus]	sp|O95407|TNF6B_HUMAN	sp|O95407|TNF6B_HUMAN Tumor necrosis factor receptor superfamily member 6B OS=Homo sapiens GN=TNFRSF6B PE=1 SV=1	9031.ENSGALP00000007029	"tumor necrosis factor receptor superfamily, member 1B "	_	_	NOG42764	PF00020.15|TNFR_c6|TNFR/NGFR cysteine-rich region|ENSGALT00000061967|m.4264:82-122
ENSGALG00000034229	7.105047776	16.66068197	-1.228367774	5.86E-22	6.16E-21	down	yes	7.745302169	5.80552835	7.76431281	17.29617123	15.13399342	17.55188125	22	2479921	2481932	+	ZNF703	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0017015|regulation of transforming growth factor beta receptor signaling pathway; GO:0030335|positive regulation of cell migration; GO:0034111|negative regulation of homotypic cell-cell adhesion; GO:0034333|adherens junction assembly; GO:0045892|negative regulation of transcription, DNA-templated; GO:0051726|regulation of cell cycle; GO:0060828|regulation of canonical Wnt signaling pathway"	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0016363|nuclear matrix	GO:0003676|nucleic acid binding; GO:0046872|metal ion binding	--	--	1830	XP_015152915.2	XP_015152915.2 zinc finger protein 703 [Gallus gallus]	sp|Q7ZWN6|Z703A_XENLA	sp|Q7ZWN6|Z703A_XENLA Zinc finger protein 703-A OS=Xenopus laevis GN=znf703-a PE=2 SV=2	8364.ENSXETP00000052626	Zfp503_predicted-prov protein; May function as a transcriptional repressor (By similarity)	_	_	NOG72624	PF12402.5|nlz1|NocA-like zinc-finger protein 1|ENSGALT00000048218|m.4703:340-393
ENSGALG00000034303	0.545402304	1.105780943	-1.00644875	0.008603265	0.015379976	down	yes	0.569147637	0.724783414	0.342275861	1.23943283	1.018854719	1.059055281	3	18739694	18743264	-	C1orf115	protein_coding	--	GO:0016021|integral component of membrane	--	--	--	1759	XP_429841.2	XP_429841.2 uncharacterized protein C1orf115 homolog [Gallus gallus]	sp|Q3ZCQ0|CA115_RAT	sp|Q3ZCQ0|CA115_RAT Uncharacterized protein C1orf115 homolog OS=Rattus norvegicus PE=2 SV=2	_	_	_	_	_	PF15828.2|DUF4710|Domain of unknown function (DUF4710)|ENSGALT00000070936|m.11129:61-127
ENSGALG00000034337	7.962805695	16.11806277	-1.016413744	1.42E-19	1.30E-18	down	yes	8.1981212	7.133152196	8.55714369	14.75495935	17.17612452	16.42310443	2	148431659	148455296	+	RHPN1	protein_coding	GO:0007165|signal transduction	GO:0005829|cytosol	GO:0030695|GTPase regulator activity	--	--	2031	XP_418410.3	XP_418410.3 rhophilin-1 isoform X2 [Gallus gallus]	sp|Q61085|RHPN1_MOUSE	sp|Q61085|RHPN1_MOUSE Rhophilin-1 OS=Mus musculus GN=Rhpn1 PE=1 SV=2	_	_	_	_	_	PF03097.15|BRO1|BRO1-like domain|ENSGALT00000063538|m.2646:123-522;PF02185.13|HR1|Hr1 repeat|ENSGALT00000063538|m.2646:50-112;PF00595.21|PDZ|PDZ domain (Also known as DHR or GLGF)|ENSGALT00000063538|m.2646:528-596
ENSGALG00000034373	3.34116969	7.784746121	-1.217837294	2.06E-20	1.98E-19	down	yes	3.658649708	2.694500703	3.670358659	7.66736913	8.106978335	7.579890898	11	491168	508560	-	KATNB1	protein_coding	GO:0007026|negative regulation of microtubule depolymerization; GO:0007049|cell cycle; GO:0031117|positive regulation of microtubule depolymerization; GO:0051301|cell division	GO:0000922|spindle pole; GO:0005634|nucleus; GO:0005813|centrosome; GO:0005829|cytosol; GO:0005874|microtubule; GO:0005886|plasma membrane; GO:0008352|katanin complex; GO:0030424|axon	GO:0008017|microtubule binding; GO:0008568|microtubule-severing ATPase activity; GO:0046982|protein heterodimerization activity; GO:0070840|dynein complex binding	ko:K18643|KATNB1	--	3226	NP_001025730.2	NP_001025730.2 katanin p80 WD40 repeat-containing subunit B1 [Gallus gallus]	sp|Q5ZIU8|KTNB1_CHICK	sp|Q5ZIU8|KTNB1_CHICK Katanin p80 WD40 repeat-containing subunit B1 OS=Gallus gallus GN=KATNB1 PE=2 SV=2	_	_	_	_	_	"PF13925.3|Katanin_con80|con80 domain of Katanin|ENSGALT00000073460|m.6145:495-653;PF00400.29|WD40|WD domain, G-beta repeat|ENSGALT00000073460|m.6145:12-49;PF00400.29|WD40|WD domain, G-beta repeat|ENSGALT00000073460|m.6145:54-91;PF00400.29|WD40|WD domain, G-beta repeat|ENSGALT00000073460|m.6145:96-133;PF00400.29|WD40|WD domain, G-beta repeat|ENSGALT00000073460|m.6145:139-175;PF00400.29|WD40|WD domain, G-beta repeat|ENSGALT00000073460|m.6145:180-217;PF12894.4|ANAPC4_WD40|Anaphase-promoting complex subunit 4 WD40 domain|ENSGALT00000073460|m.6145:72-153;PF12894.4|ANAPC4_WD40|Anaphase-promoting complex subunit 4 WD40 domain|ENSGALT00000073460|m.6145:144-190"
ENSGALG00000034456	0.116199875	0.801618219	-2.685090769	6.23E-08	2.27E-07	down	yes	0.264021205	0.041481552	0.043096868	0.829957033	0.760770072	0.81412755	26	5152468	5174115	+	PRELP	protein_coding	--	GO:0005615|extracellular space; GO:0031012|extracellular matrix; GO:0070062|extracellular exosome	GO:0005201|extracellular matrix structural constituent; GO:0008201|heparin binding	ko:K08125|PRELP	--	2794	POI34642.1	"POI34642.1 hypothetical protein CIB84_001606, partial [Bambusicola thoracicus]"	sp|Q9GKN8|PRELP_BOVIN	sp|Q9GKN8|PRELP_BOVIN Prolargin OS=Bos taurus GN=PRELP PE=2 SV=1	9031.ENSGALP00000005607	proline/arginine-rich end leucine-rich repeat protein	COG4886	KOG0619	_	PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000080130|m.8319:150-209;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000080130|m.8319:218-278;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000080130|m.8319:292-350;PF00560.30|LRR_1|Leucine Rich Repeat|ENSGALT00000080130|m.8319:359-377;PF01462.15|LRRNT|Leucine rich repeat N-terminal domain|ENSGALT00000080130|m.8319:119-148
ENSGALG00000034478	14.18418878	32.77671267	-1.20781086	0.000432783	0.000963929	down	yes	15.47278013	10.8336353	16.24615089	40.84527341	20.75643818	36.72842643	19	576608	578177	+	CCL4	protein_coding	GO:0002548|monocyte chemotaxis; GO:0006954|inflammatory response; GO:0007186|G protein-coupled receptor signaling pathway; GO:0030593|neutrophil chemotaxis; GO:0043547|positive regulation of GTPase activity; GO:0048247|lymphocyte chemotaxis; GO:0070098|chemokine-mediated signaling pathway; GO:0070374|positive regulation of ERK1 and ERK2 cascade; GO:0071346|cellular response to interferon-gamma; GO:0071347|cellular response to interleukin-1; GO:0071356|cellular response to tumor necrosis factor	GO:0005615|extracellular space	GO:0008009|chemokine activity; GO:0048020|CCR chemokine receptor binding	--	--	756	POI33106.1	"POI33106.1 hypothetical protein CIB84_003142, partial [Bambusicola thoracicus]"	sp|Q711P4|CCL4_PIG	sp|Q711P4|CCL4_PIG C-C motif chemokine 4 OS=Sus scrofa GN=CCL4 PE=3 SV=1	9031.ENSGALP00000001408	chemokine K203 	_	_	NOG42742	"PF00048.17|IL8|Small cytokines (intecrine/chemokine), interleukin-8 like|ENSGALT00000053861|m.13507:47-101"
ENSGALG00000034500	34.44961425	75.93934121	-1.140130899	6.20E-56	2.68E-54	down	yes	31.66427426	36.17736628	35.50720221	75.04406004	74.07152744	78.70243616	2	97261548	97270754	-	CIDEA	protein_coding	"GO:0001659|temperature homeostasis; GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated; GO:0006629|lipid metabolic process; GO:0006915|apoptotic process; GO:0008219|cell death; GO:0010890|positive regulation of sequestering of triglyceride; GO:0019915|lipid storage; GO:0030512|negative regulation of transforming growth factor beta receptor signaling pathway; GO:0032720|negative regulation of tumor necrosis factor production; GO:0034389|lipid droplet organization; GO:0035634|response to stilbenoid; GO:0042981|regulation of apoptotic process; GO:0050710|negative regulation of cytokine secretion; GO:0050995|negative regulation of lipid catabolic process; GO:1900118|negative regulation of execution phase of apoptosis; GO:1902510|regulation of apoptotic DNA fragmentation"	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005739|mitochondrion; GO:0005740|mitochondrial envelope; GO:0005811|lipid droplet; GO:0005829|cytosol	GO:0042803|protein homodimerization activity	--	--	1699	NP_001182052.1	NP_001182052.1 cell death activator CIDE-A [Gallus gallus]	sp|O60543|CIDEA_HUMAN	sp|O60543|CIDEA_HUMAN Cell death activator CIDE-A OS=Homo sapiens GN=CIDEA PE=1 SV=1	_	_	_	_	_	PF02017.12|CIDE-N|CIDE-N domain|ENSGALT00000048459|m.1485:54-128
ENSGALG00000034511	2.731310299	10.14125766	-1.888720931	2.21E-43	6.33E-42	down	yes	2.151388463	2.99705979	3.045482643	11.00567587	9.309895145	10.10820197	1	56624328	56633715	-	ENSGALG00000034511	protein_coding	--	GO:0005634|nucleus	GO:0003723|RNA binding; GO:0003950|NAD+ ADP-ribosyltransferase activity; GO:0046872|metal ion binding	ko:K15259|PARP7S	--	2298	XP_416342.1	XP_416342.1 poly [ADP-ribose] polymerase 12 [Gallus gallus]	sp|Q8BZ20|PAR12_MOUSE	sp|Q8BZ20|PAR12_MOUSE Poly [ADP-ribose] polymerase 12 OS=Mus musculus GN=Parp12 PE=1 SV=3	9031.ENSGALP00000020914	hypothetical LOC418108	_	KOG4177	_	PF00644.17|PARP|Poly(ADP-ribose) polymerase catalytic domain|ENSGALT00000091540|m.1648:54-234
ENSGALG00000034512	2.336847297	1.021122952	1.186507601	9.12E-08	3.26E-07	up	yes	2.153702954	2.501539606	2.35529933	1.211156743	0.995150835	0.857061278	9	648810	655576	+	ENSGALG00000034512	protein_coding	GO:0001754|eye photoreceptor cell differentiation; GO:0006470|protein dephosphorylation; GO:0007525|somatic muscle development; GO:0045732|positive regulation of protein catabolic process; GO:0061053|somite development; GO:0090090|negative regulation of canonical Wnt signaling pathway; GO:0090244|Wnt signaling pathway involved in somitogenesis; GO:0090249|regulation of cell motility involved in somitogenic axis elongation; GO:0090263|positive regulation of canonical Wnt signaling pathway	GO:0000159|protein phosphatase type 2A complex	"GO:0005509|calcium ion binding; GO:0019888|protein phosphatase regulator activity; GO:0030674|protein binding, bridging"	ko:K11583|PPP2R3	ko03015|mRNA surveillance pathway; ko04071|Sphingolipid signaling pathway; ko04151|PI3K-Akt signaling pathway; ko04152|AMPK signaling pathway; ko04261|Adrenergic signaling in cardiomyocytes; ko04728|Dopaminergic synapse	2471	XP_422556.4	XP_422556.4 serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X1 [Gallus gallus]	sp|Q06190|P2R3A_HUMAN	sp|Q06190|P2R3A_HUMAN Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha OS=Homo sapiens GN=PPP2R3A PE=1 SV=1	9031.ENSGALP00000001832	"protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha"	_	KOG2562	_	_
ENSGALG00000034615	3.759969138	1.833816287	1.031857797	2.48E-09	1.03E-08	up	yes	3.751160491	4.102223109	3.426523814	1.590355641	1.621869187	2.289224032	28	3514797	3523166	-	ANO8	protein_coding	GO:0006821|chloride transport; GO:0034220|ion transmembrane transport; GO:0043687|post-translational protein modification; GO:0044267|cellular protein metabolic process	GO:0005788|endoplasmic reticulum lumen; GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0005229|intracellular calcium activated chloride channel activity	"ko:K19502|ANO8,TMEM16H"	--	3315	XP_025000159.1	XP_025000159.1 anoctamin-8 [Gallus gallus]	sp|Q9HCE9|ANO8_HUMAN	sp|Q9HCE9|ANO8_HUMAN Anoctamin-8 OS=Homo sapiens GN=ANO8 PE=1 SV=3	_	_	_	_	_	PF04547.9|Anoctamin|Calcium-activated chloride channel|ENSGALT00000046530|m.10249:235-489;PF04547.9|Anoctamin|Calcium-activated chloride channel|ENSGALT00000046530|m.10249:510-871
ENSGALG00000034649	1.911823998	5.726773155	-1.577763252	2.36E-26	3.16E-25	down	yes	1.82918616	2.141997954	1.76428788	6.697301916	4.939145196	5.543872354	11	5223979	5345307	+	TOX3	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006915|apoptotic process; GO:0042981|regulation of apoptotic process; GO:0043524|negative regulation of neuron apoptotic process; GO:0045893|positive regulation of transcription, DNA-templated"	GO:0005634|nucleus	GO:0003682|chromatin binding; GO:0034056|estrogen response element binding; GO:0042803|protein homodimerization activity; GO:0051219|phosphoprotein binding	--	--	3888	NP_001264067.1	NP_001264067.1 TOX high mobility group box family member 3 isoform 2 [Gallus gallus]	sp|O15405|TOX3_HUMAN	sp|O15405|TOX3_HUMAN TOX high mobility group box family member 3 OS=Homo sapiens GN=TOX3 PE=1 SV=2	9031.ENSGALP00000005919	TOX high mobility group box family member 3	_	KOG0381	_	PF00505.16|HMG_box|HMG (high mobility group) box|ENSGALT00000065574|m.6491:245-313;PF09011.7|HMG_box_2|HMG-box domain|ENSGALT00000065574|m.6491:242-307
ENSGALG00000034661	2.787568815	15.69458457	-2.488940256	5.20E-36	1.08E-34	down	yes	3.299257881	2.845904405	2.217544159	13.06710397	19.55347761	14.46317213	20	10006753	10007982	+	ID1	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0001525|angiogenesis; GO:0001886|endothelial cell morphogenesis; GO:0006351|transcription, DNA-templated; GO:0007179|transforming growth factor beta receptor signaling pathway; GO:0007420|brain development; GO:0007507|heart development; GO:0007623|circadian rhythm; GO:0010621|negative regulation of transcription by transcription factor localization; GO:0010628|positive regulation of gene expression; GO:0030182|neuron differentiation; GO:0030509|BMP signaling pathway; GO:0031648|protein destabilization; GO:0032233|positive regulation of actin filament bundle assembly; GO:0032963|collagen metabolic process; GO:0036164|cell-abiotic substrate adhesion; GO:0043066|negative regulation of apoptotic process; GO:0043408|regulation of MAPK cascade; GO:0043433|negative regulation of DNA-binding transcription factor activity; GO:0043534|blood vessel endothelial cell migration; GO:0045602|negative regulation of endothelial cell differentiation; GO:0045668|negative regulation of osteoblast differentiation; GO:0045765|regulation of angiogenesis; GO:0045892|negative regulation of transcription, DNA-templated; GO:0046677|response to antibiotic; GO:0048514|blood vessel morphogenesis; GO:0050679|positive regulation of epithelial cell proliferation; GO:0050774|negative regulation of dendrite morphogenesis; GO:0060425|lung morphogenesis; GO:0060426|lung vasculature development; GO:0071364|cellular response to epidermal growth factor stimulus; GO:0090074|negative regulation of protein homodimerization activity; GO:1901653|cellular response to peptide; GO:1903026|negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding; GO:1903351|cellular response to dopamine; GO:1990090|cellular response to nerve growth factor stimulus"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005794|Golgi apparatus; GO:0005813|centrosome	GO:0003700|DNA-binding transcription factor activity; GO:0008022|protein C-terminus binding; GO:0008134|transcription factor binding; GO:0042803|protein homodimerization activity; GO:0043621|protein self-association; GO:0047485|protein N-terminus binding; GO:0070628|proteasome binding	ko:K04680|ID1	ko04015|Rap1 signaling pathway; ko04350|TGF-beta signaling pathway; ko04390|Hippo signaling pathway; ko04550|Signaling pathways regulating pluripotency of stem cells	1086	NP_989921.1	NP_989921.1 DNA-binding protein inhibitor ID-1 [Gallus gallus]	sp|P41134|ID1_HUMAN	sp|P41134|ID1_HUMAN DNA-binding protein inhibitor ID-1 OS=Homo sapiens GN=ID1 PE=1 SV=3	9031.ENSGALP00000010011	"inhibitor of DNA binding 1, dominant negative helix-loop-helix protein "	_	_	NOG77422	PF00010.23|HLH|Helix-loop-helix DNA-binding domain|ENSGALT00000052019|m.3392:49-87
ENSGALG00000034737	11.9496198	5.666717662	1.075042632	0.000293766	0.00067125	up	yes	12.07609171	7.708145697	16.06462199	5.457518186	5.284564867	6.258069933	14	13089512	13093771	+	ENSGALG00000034737	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0007399|nervous system development; GO:0043433|negative regulation of DNA-binding transcription factor activity; GO:0045879|negative regulation of smoothened signaling pathway; GO:0045892|negative regulation of transcription, DNA-templated; GO:0045893|positive regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0060994|regulation of transcription from RNA polymerase II promoter involved in kidney development; GO:0061005|cell differentiation involved in kidney development; GO:1900182|positive regulation of protein localization to nucleus"	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0016607|nuclear speck; GO:0097730|non-motile cilium	"GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0044212|transcription regulatory region DNA binding; GO:0046872|metal ion binding"	ko:K09233|GLIS2	--	4147	XP_025011119.1	XP_025011119.1 LOW QUALITY PROTEIN: zinc finger protein GLIS2 [Gallus gallus]	sp|Q9BZE0|GLIS2_HUMAN	sp|Q9BZE0|GLIS2_HUMAN Zinc finger protein GLIS2 OS=Homo sapiens GN=GLIS2 PE=1 SV=2	_	_	_	_	_	PF13912.3|zf-C2H2_6|C2H2-type zinc finger|ENSGALT00000101111|m.9889:14-37
ENSGALG00000034751	1.079464301	2.44629407	-1.172864369	6.80E-10	2.98E-09	down	yes	1.137321322	0.960551054	1.140520526	2.106515532	2.687451052	2.544915627	2	117290673	117324784	-	TRPA1	protein_coding	GO:0006816|calcium ion transport; GO:0007166|cell surface receptor signaling pathway; GO:0009409|response to cold; GO:0010033|response to organic substance; GO:0014070|response to organic cyclic compound; GO:0019233|sensory perception of pain; GO:0042493|response to drug; GO:0042542|response to hydrogen peroxide; GO:0048265|response to pain; GO:0050955|thermoception; GO:0050966|detection of mechanical stimulus involved in sensory perception of pain; GO:0050968|detection of chemical stimulus involved in sensory perception of pain; GO:0051289|protein homotetramerization; GO:0070588|calcium ion transmembrane transport	GO:0005887|integral component of plasma membrane; GO:0016021|integral component of membrane; GO:0032421|stereocilium bundle	GO:0005216|ion channel activity; GO:0005262|calcium channel activity; GO:0015267|channel activity; GO:0015278|calcium-release channel activity; GO:0042802|identical protein binding; GO:0097604|temperature-gated cation channel activity	"ko:K04984|TRPA1,ANKTM1"	ko04750|Inflammatory mediator regulation of TRP channels	3573	NP_001305389.1	NP_001305389.1 transient receptor potential cation channel subfamily A member 1 [Gallus gallus]	sp|Q8BLA8|TRPA1_MOUSE	sp|Q8BLA8|TRPA1_MOUSE Transient receptor potential cation channel subfamily A member 1 OS=Mus musculus GN=Trpa1 PE=1 SV=1	9031.ENSGALP00000025157	"transient receptor potential cation channel, subfamily A, member 1"	COG0666	KOG0510	_	PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000064071|m.1926:67-131;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000064071|m.1926:140-228;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000064071|m.1926:207-299;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000064071|m.1926:407-472;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000064071|m.1926:480-546;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000064071|m.1926:551-605;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000064071|m.1926:70-123;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000064071|m.1926:137-190;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000064071|m.1926:246-295;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000064071|m.1926:453-507;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000064071|m.1926:487-533;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000064071|m.1926:520-573;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000064071|m.1926:103-133;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000064071|m.1926:347-377;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000064071|m.1926:418-438;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000064071|m.1926:487-511;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000064071|m.1926:553-578;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000064071|m.1926:103-131;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000064071|m.1926:245-271;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000064071|m.1926:487-511;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000064071|m.1926:552-579;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000064071|m.1926:480-526;PF00520.28|Ion_trans|Ion transport protein|ENSGALT00000064071|m.1926:774-971
ENSGALG00000034860	4.720736793	1.826584217	1.365039842	1.48E-19	1.36E-18	up	yes	5.358810742	3.638674083	5.164725553	1.800990342	1.948917383	1.729844926	9	21107790	21154158	+	BCHE	protein_coding	--	GO:0005641|nuclear envelope lumen; GO:0005783|endoplasmic reticulum; GO:0072562|blood microparticle	GO:0003990|acetylcholinesterase activity; GO:0004104|cholinesterase activity; GO:0042802|identical protein binding; GO:0052689|carboxylic ester hydrolase activity	ko:K01050|BCHE	--	4324	XP_015147122.1	XP_015147122.1 cholinesterase isoform X1 [Gallus gallus]	sp|P32749|CHLE_BOVIN	sp|P32749|CHLE_BOVIN Cholinesterase OS=Bos taurus GN=BCHE PE=2 SV=2	9031.ENSGALP00000015414	butyrylcholinesterase 	COG2272	KOG4389	_	PF00135.25|COesterase|Carboxylesterase family|ENSGALT00000093801|m.9292:31-550;PF08674.7|AChE_tetra|Acetylcholinesterase tetramerisation domain|ENSGALT00000093801|m.9292:565-601
ENSGALG00000034876	26.58830675	12.1309149	1.131457264	4.60E-49	1.62E-47	up	yes	28.16424525	27.0732567	24.52741829	12.53061004	11.56941666	12.292718	2	125806946	125814561	+	PDP1	protein_coding	GO:0010510|regulation of acetyl-CoA biosynthetic process from pyruvate; GO:0035970|peptidyl-threonine dephosphorylation	GO:0005759|mitochondrial matrix	GO:0004722|protein serine/threonine phosphatase activity; GO:0004741|[pyruvate dehydrogenase (lipoamide)] phosphatase activity; GO:0046872|metal ion binding	ko:K01102|PDP	--	4072	NP_001186839.1	NP_001186839.1 pyruvate dehyrogenase phosphatase catalytic subunit 1 [Gallus gallus]	sp|Q9P0J1|PDP1_HUMAN	"sp|Q9P0J1|PDP1_HUMAN [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial OS=Homo sapiens GN=PDP1 PE=1 SV=3"	9031.ENSGALP00000025645	"protein phosphatase 2C, magnesium-dependent, catalytic subunit"	COG0631	KOG0700	_	PF00481.18|PP2C|Protein phosphatase 2C|ENSGALT00000104051|m.2122:251-482
ENSGALG00000034907	2.220246759	0.382432079	2.50668846	1.76E-17	1.41E-16	up	yes	2.138437058	2.11144393	2.410859291	0.42899692	0.304467855	0.413831461	27	6226468	6229290	+	HOXB5	protein_coding	"GO:0006355|regulation of transcription, DNA-templated; GO:0009952|anterior/posterior pattern specification; GO:0045446|endothelial cell differentiation; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0048704|embryonic skeletal system morphogenesis; GO:0048706|embryonic skeletal system development"	GO:0001650|fibrillar center; GO:0005634|nucleus; GO:0005829|cytosol	"GO:0000980|RNA polymerase II distal enhancer sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity"	ko:K09305|HOX_5	--	1848	NP_001020526.1	NP_001020526.1 homeobox protein Hox-B5 [Gallus gallus]	sp|P09079|HXB5_MOUSE	sp|P09079|HXB5_MOUSE Homeobox protein Hox-B5 OS=Mus musculus GN=Hoxb5 PE=2 SV=3	_	_	_	_	_	PF00046.26|Homeobox|Homeobox domain|ENSGALT00000058059|m.9044:190-246
ENSGALG00000034965	30.29952958	61.14433888	-1.0126834	1.95E-50	7.14E-49	down	yes	30.10494826	30.94138537	29.85225511	55.60980853	64.5272651	63.295943	33	5645989	5704717	-	DIP2B	protein_coding	GO:0008152|metabolic process	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0016020|membrane; GO:0070062|extracellular exosome	GO:0003824|catalytic activity	--	--	5122	XP_004949780.1	XP_004949780.1 disco-interacting protein 2 homolog B isoform X1 [Gallus gallus]	sp|Q3UH60|DIP2B_MOUSE	sp|Q3UH60|DIP2B_MOUSE Disco-interacting protein 2 homolog B OS=Mus musculus GN=Dip2b PE=1 SV=1	9031.ENSGALP00000009895	DIP2 disco-interacting protein 2 homolog B (Drosophila)	COG0318	KOG3628	_	PF00501.25|AMP-binding|AMP-binding enzyme|ENSGALT00000091790|m.15188:353-812;PF00501.25|AMP-binding|AMP-binding enzyme|ENSGALT00000091790|m.15188:991-1465;PF06464.8|DMAP_binding|DMAP1-binding Domain|ENSGALT00000091790|m.15188:10-131
ENSGALG00000034973	4.264195009	9.349522803	-1.130782243	3.35E-20	3.19E-19	down	yes	4.355202288	3.696110242	4.741272498	8.47479018	9.778727631	9.795050598	7	11682384	11685456	+	FZD7	protein_coding	GO:0007275|multicellular organism development; GO:0035567|non-canonical Wnt signaling pathway; GO:0060070|canonical Wnt signaling pathway	GO:0005886|plasma membrane; GO:0010008|endosome membrane; GO:0016021|integral component of membrane	GO:0004930|G protein-coupled receptor activity; GO:0017147|Wnt-protein binding; GO:0042813|Wnt-activated receptor activity	"ko:K02432|FZD1_7,fz"	ko04150|mTOR signaling pathway; ko04310|Wnt signaling pathway; ko04390|Hippo signaling pathway; ko04550|Signaling pathways regulating pluripotency of stem cells; ko04916|Melanogenesis; ko05166|HTLV-I infection; ko05200|Pathways in cancer; ko05205|Proteoglycans in cancer; ko05217|Basal cell carcinoma; ko05224|Breast cancer	3073	NP_989552.1	NP_989552.1 frizzled-7 precursor [Gallus gallus]	sp|O57329|FZD7_CHICK	sp|O57329|FZD7_CHICK Frizzled-7 OS=Gallus gallus GN=FZD7 PE=2 SV=1	9031.ENSGALP00000030969	Frizzled-7 Precursor (Fz-7)(cFz-7); Receptor for Wnt proteins. Most of frizzled receptors ar [...] 	_	KOG3577	_	PF01534.14|Frizzled|Frizzled/Smoothened family membrane region|ENSGALT00000048401|m.5900:356-674;PF01392.19|Fz|Fz domain|ENSGALT00000048401|m.5900:165-269
ENSGALG00000034992	0.763119805	1.845143967	-1.26276725	2.82E-06	8.52E-06	down	yes	0.728679821	0.718499256	0.842180338	1.795772515	1.888142727	1.851516659	1	7410004	7438493	-	FRMD4A	protein_coding	GO:0090162|establishment of epithelial cell polarity	GO:0005737|cytoplasm; GO:0005856|cytoskeleton; GO:0005912|adherens junction; GO:0005923|bicellular tight junction	"GO:0030674|protein binding, bridging"	--	--	2097	XP_015154200.1	XP_015154200.1 FERM domain-containing protein 4A isoform X1 [Gallus gallus]	sp|Q8BIE6|FRM4A_MOUSE	sp|Q8BIE6|FRM4A_MOUSE FERM domain-containing protein 4A OS=Mus musculus GN=Frmd4a PE=1 SV=2	9031.ENSGALP00000010751	"PREDICTED: Gallus gallus hypothetical LOC419035 (LOC419035), mRNA"	_	KOG3529	_	PF11819.5|DUF3338|Domain of unknown function (DUF3338)|ENSGALT00000059565|m.338:48-182
ENSGALG00000035016	10.66985535	56.77814928	-2.410697788	6.41E-95	7.11E-93	down	yes	9.910292925	11.40979109	10.68948203	54.96104043	68.41282263	46.96058478	3	95853920	95856597	+	ID2	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0007275|multicellular organism development; GO:0010628|positive regulation of gene expression; GO:0010629|negative regulation of gene expression; GO:0019216|regulation of lipid metabolic process; GO:0032922|circadian regulation of gene expression; GO:0033598|mammary gland epithelial cell proliferation; GO:0042752|regulation of circadian rhythm; GO:0043153|entrainment of circadian clock by photoperiod; GO:0043433|negative regulation of DNA-binding transcription factor activity; GO:0045475|locomotor rhythm; GO:0045665|negative regulation of neuron differentiation; GO:0045777|positive regulation of blood pressure; GO:0045892|negative regulation of transcription, DNA-templated; GO:0045893|positive regulation of transcription, DNA-templated; GO:0048557|embryonic digestive tract morphogenesis; GO:0048661|positive regulation of smooth muscle cell proliferation; GO:0048663|neuron fate commitment; GO:0060749|mammary gland alveolus development; GO:0061030|epithelial cell differentiation involved in mammary gland alveolus development; GO:0061031|endodermal digestive tract morphogenesis; GO:0071158|positive regulation of cell cycle arrest; GO:0071931|positive regulation of transcription involved in G1/S transition of mitotic cell cycle; GO:0090398|cellular senescence; GO:2000045|regulation of G1/S transition of mitotic cell cycle; GO:2000178|negative regulation of neural precursor cell proliferation"	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0032991|protein-containing complex	GO:0044325|ion channel binding; GO:0046983|protein dimerization activity	ko:K17693|ID2	ko04350|TGF-beta signaling pathway; ko04390|Hippo signaling pathway; ko04550|Signaling pathways regulating pluripotency of stem cells; ko05202|Transcriptional misregulation in cancer	1930	NP_990333.1	NP_990333.1 DNA-binding protein inhibitor ID-2 [Gallus gallus]	sp|Q02363|ID2_HUMAN	sp|Q02363|ID2_HUMAN DNA-binding protein inhibitor ID-2 OS=Homo sapiens GN=ID2 PE=1 SV=1	_	_	_	_	_	PF00010.23|HLH|Helix-loop-helix DNA-binding domain|ENSGALT00000079911|m.12929:66-105
ENSGALG00000035017	15.6644407	53.00269943	-1.757924039	1.93E-120	4.32E-118	down	yes	16.26437629	15.27614618	15.45279964	56.40780934	48.08362633	54.51666262	21	2682333	2709511	-	ENSGALG00000035017	protein_coding	GO:0000077|DNA damage checkpoint; GO:0000187|activation of MAPK activity; GO:0006641|triglyceride metabolic process; GO:0007173|epidermal growth factor receptor signaling pathway; GO:0007229|integrin-mediated signaling pathway; GO:0007409|axonogenesis; GO:0009755|hormone-mediated signaling pathway; GO:0021697|cerebellar cortex formation; GO:0030220|platelet formation; GO:0032528|microvillus organization; GO:0033277|abortive mitotic cell cycle; GO:0033629|negative regulation of cell adhesion mediated by integrin; GO:0035264|multicellular organism growth; GO:0035265|organ growth; GO:0035855|megakaryocyte development; GO:0036302|atrioventricular canal development; GO:0040014|regulation of multicellular organism growth; GO:0042445|hormone metabolic process; GO:0042593|glucose homeostasis; GO:0043254|regulation of protein complex assembly; GO:0045931|positive regulation of mitotic cell cycle; GO:0046676|negative regulation of insulin secretion; GO:0046825|regulation of protein export from nucleus; GO:0046887|positive regulation of hormone secretion; GO:0048008|platelet-derived growth factor receptor signaling pathway; GO:0048011|neurotrophin TRK receptor signaling pathway; GO:0048013|ephrin receptor signaling pathway; GO:0048609|multicellular organismal reproductive process; GO:0048806|genitalia development; GO:0048839|inner ear development; GO:0048873|homeostasis of number of cells within a tissue; GO:0051463|negative regulation of cortisol secretion; GO:0060020|Bergmann glial cell differentiation; GO:0060125|negative regulation of growth hormone secretion; GO:0060325|face morphogenesis; GO:0061582|intestinal epithelial cell migration; GO:0070374|positive regulation of ERK1 and ERK2 cascade; GO:0071364|cellular response to epidermal growth factor stimulus	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0032991|protein-containing complex	GO:0004725|protein tyrosine phosphatase activity; GO:0004726|non-membrane spanning protein tyrosine phosphatase activity; GO:0005070|SH3/SH2 adaptor activity; GO:0005158|insulin receptor binding; GO:0030971|receptor tyrosine kinase binding; GO:0050839|cell adhesion molecule binding; GO:0051428|peptide hormone receptor binding	ko:K07293|PTPN11	ko04013|MAPK signaling pathway - fly; ko04014|Ras signaling pathway; ko04072|Phospholipase D signaling pathway; ko04360|Axon guidance; ko04630|Jak-STAT signaling pathway; ko04650|Natural killer cell mediated cytotoxicity; ko04670|Leukocyte transendothelial migration; ko04722|Neurotrophin signaling pathway; ko04920|Adipocytokine signaling pathway; ko04931|Insulin resistance; ko05120|Epithelial cell signaling in Helicobacter pylori infection; ko05168|Herpes simplex infection; ko05205|Proteoglycans in cancer; ko05211|Renal cell carcinoma; ko05220|Chronic myeloid leukemia	3492	XP_015152367.1	"XP_015152367.1 protein tyrosine phosphatase, non-receptor type 11-like isoform X1 [Gallus gallus]"	sp|Q90687|PTN11_CHICK	sp|Q90687|PTN11_CHICK Tyrosine-protein phosphatase non-receptor type 11 OS=Gallus gallus GN=PTPN11 PE=2 SV=1	9031.ENSGALP00000003116	hypothetical protein LOC419429 	COG5599	KOG0790	_	PF00102.24|Y_phosphatase|Protein-tyrosine phosphatase|ENSGALT00000092686|m.3946:282-492;PF00017.21|SH2|SH2 domain|ENSGALT00000092686|m.3946:14-89;PF00017.21|SH2|SH2 domain|ENSGALT00000092686|m.3946:120-206
ENSGALG00000035028	8.670359965	4.22959376	1.033828839	1.65E-10	7.66E-10	up	yes	10.04288977	7.296817898	8.671372223	4.281866541	3.324915596	5.081999144	33	6827441	6840335	-	NAB2	protein_coding	"GO:0001958|endochondral ossification; GO:0006351|transcription, DNA-templated; GO:0007399|nervous system development; GO:0008283|cell population proliferation; GO:0014037|Schwann cell differentiation; GO:0016480|negative regulation of transcription by RNA polymerase III; GO:0042552|myelination; GO:0045682|regulation of epidermis development; GO:1902949|positive regulation of tau-protein kinase activity"	GO:0005634|nucleus	GO:0003714|transcription corepressor activity; GO:0008134|transcription factor binding; GO:0042802|identical protein binding	--	--	2319	XP_025001290.1	XP_025001290.1 NGFI-A-binding protein 2 [Gallus gallus]	sp|Q15742|NAB2_HUMAN	sp|Q15742|NAB2_HUMAN NGFI-A-binding protein 2 OS=Homo sapiens GN=NAB2 PE=1 SV=1	_	_	_	_	_	PF04905.10|NCD2|NAB conserved region 2 (NCD2)|ENSGALT00000100584|m.15471:235-370;PF04904.10|NCD1|NAB conserved region 1 (NCD1)|ENSGALT00000100584|m.15471:65-141
ENSGALG00000035086	129.1639817	59.73329849	1.112466713	2.07E-82	1.79E-80	up	yes	130.8237895	129.4198552	127.2483003	58.84076794	60.1123841	60.24674344	33	7016255	7020910	-	MYL6	protein_coding	GO:0030239|myofibril assembly; GO:0031032|actomyosin structure organization	GO:0005829|cytosol; GO:0005859|muscle myosin complex; GO:0016460|myosin II complex; GO:0042641|actomyosin; GO:0097513|myosin II filament	GO:0000287|magnesium ion binding; GO:0005509|calcium ion binding; GO:0008307|structural constituent of muscle; GO:0016887|ATPase activity; GO:0030898|actin-dependent ATPase activity; GO:0032036|myosin heavy chain binding; GO:0043531|ADP binding; GO:0045159|myosin II binding; GO:0046982|protein heterodimerization activity	ko:K12751|MYL6	ko04270|Vascular smooth muscle contraction; ko04530|Tight junction; ko04921|Oxytocin signaling pathway	1487	NP_001290154.1	NP_001290154.1 myosin light polypeptide 6 [Meleagris gallopavo]	sp|P02607|MYL6_CHICK	sp|P02607|MYL6_CHICK Myosin light polypeptide 6 OS=Gallus gallus GN=MYL6 PE=1 SV=3	_	_	_	_	_	PF13405.3|EF-hand_6|EF-hand domain|ENSGALT00000061061|m.15608:135-164
ENSGALG00000035108	19.74400017	45.70743251	-1.210599557	8.28E-60	4.07E-58	down	yes	20.86878603	19.50054354	18.86267094	42.6854894	47.19430615	47.24250197	1	56677151	56731558	-	KDM7A	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0030901|midbrain development; GO:0033169|histone H3-K9 demethylation; GO:0035574|histone H4-K20 demethylation; GO:0045893|positive regulation of transcription, DNA-templated; GO:0070544|histone H3-K36 demethylation; GO:0071557|histone H3-K27 demethylation"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005730|nucleolus	GO:0005506|iron ion binding; GO:0008270|zinc ion binding; GO:0016706|2-oxoglutarate-dependent dioxygenase activity; GO:0032452|histone demethylase activity; GO:0032454|histone demethylase activity (H3-K9 specific); GO:0035064|methylated histone binding; GO:0035575|histone demethylase activity (H4-K20 specific); GO:0051864|histone demethylase activity (H3-K36 specific); GO:0071558|histone demethylase activity (H3-K27 specific)	"ko:K11445|KDM7A,JHDM1D"	--	3045	XP_015142945.1	XP_015142945.1 lysine-specific demethylase 7A isoform X1 [Gallus gallus]	sp|Q6ZMT4|KDM7A_HUMAN	sp|Q6ZMT4|KDM7A_HUMAN Lysine-specific demethylase 7A OS=Homo sapiens GN=KDM7A PE=1 SV=2	9031.ENSGALP00000020923	jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)	_	KOG1633	_	"PF02373.19|JmjC|JmjC domain, hydroxylase|ENSGALT00000060010|m.1652:339-439;PF13621.3|Cupin_8|Cupin-like domain|ENSGALT00000060010|m.1652:267-433;PF00628.26|PHD|PHD-finger|ENSGALT00000060010|m.1652:109-156"
ENSGALG00000035129	30.02863193	12.92950627	1.215036539	1.21E-30	1.97E-29	up	yes	29.94186237	31.49427177	28.64976164	10.64988207	15.14981094	12.9888258	2	125747442	125753939	-	RBM12B	protein_coding	--	--	GO:0003723|RNA binding	--	--	2879	NP_001026115.1	NP_001026115.1 RNA-binding protein 12B [Gallus gallus]	sp|Q66JV4|R12BB_MOUSE	sp|Q66JV4|R12BB_MOUSE RNA-binding protein 12B-B OS=Mus musculus GN=Rbm12b2 PE=2 SV=2	_	_	_	_	_	"PF00076.19|RRM_1|RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)|ENSGALT00000078323|m.2118:311-377;PF00076.19|RRM_1|RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)|ENSGALT00000078323|m.2118:426-493;PF00076.19|RRM_1|RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)|ENSGALT00000078323|m.2118:625-693"
ENSGALG00000035182	0.801298653	0.300759254	1.384435742	5.74E-05	0.000145554	up	yes	0.944347432	0.833440059	0.626108469	0.309168242	0.235157825	0.357951694	15	6777719	6785231	-	CMKLR1	protein_coding	GO:0006935|chemotaxis; GO:0007186|G protein-coupled receptor signaling pathway; GO:0010759|positive regulation of macrophage chemotaxis; GO:0032088|negative regulation of NF-kappaB transcription factor activity; GO:0032695|negative regulation of interleukin-12 production; GO:0045600|positive regulation of fat cell differentiation; GO:0050848|regulation of calcium-mediated signaling	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0004930|G protein-coupled receptor activity	ko:K04245|CMKLR1	--	2521	XP_021268727.1	XP_021268727.1 chemokine-like receptor 1 isoform X1 [Numida meleagris]	sp|B1PHQ8|CML1_PIG	sp|B1PHQ8|CML1_PIG Chemokine-like receptor 1 OS=Sus scrofa GN=CMLKR1 PE=2 SV=1	9031.ENSGALP00000015767	similar to orphan G-protein coupled receptor Dez	_	KOG3656	_	PF00001.18|7tm_1|7 transmembrane receptor (rhodopsin family)|ENSGALT00000099777|m.10606:59-310
ENSGALG00000035184	6.496109468	1.342152265	2.266537474	5.43E-22	5.73E-21	up	yes	9.169282663	5.32152735	4.997518389	1.739077808	1.13389401	1.153484977	23	549584	568556	-	SDC3	protein_coding	GO:0003419|growth plate cartilage chondrocyte proliferation; GO:0016477|cell migration; GO:0030154|cell differentiation; GO:0035988|chondrocyte proliferation; GO:1900026|positive regulation of substrate adhesion-dependent cell spreading	GO:0009986|cell surface; GO:0016021|integral component of membrane	GO:0019838|growth factor binding	ko:K16337|SDC3	ko04514|Cell adhesion molecules (CAMs)	2040	NP_990714.1	NP_990714.1 syndecan-3 precursor [Gallus gallus]	sp|P26261|SDC3_CHICK	sp|P26261|SDC3_CHICK Syndecan-3 OS=Gallus gallus GN=SDC3 PE=2 SV=2	9031.ENSGALP00000000792	Syndecan-3 Precursor ; Cell surface proteoglycan that may bear both heparan sulfate and chon [...] 	_	_	NOG85596	PF01034.17|Syndecan|Syndecan domain|ENSGALT00000062640|m.5161:353-415
ENSGALG00000035194	0.13600717	0.339520884	-1.259339446	0.00788037	0.014207477	down	yes	0.208870596	0.061257641	0.137893272	0.293314173	0.346951741	0.378296738	22	437194	453936	-	ARHGAP25	protein_coding	"GO:0006911|phagocytosis, engulfment; GO:0007015|actin filament organization; GO:0007165|signal transduction; GO:0051058|negative regulation of small GTPase mediated signal transduction"	GO:0001891|phagocytic cup	GO:0005096|GTPase activator activity	ko:K20642|ARHGAP22_24_25	--	3719	NP_001026054.1	NP_001026054.1 rho GTPase-activating protein 25 [Gallus gallus]	sp|Q8BYW1|RHG25_MOUSE	sp|Q8BYW1|RHG25_MOUSE Rho GTPase-activating protein 25 OS=Mus musculus GN=Arhgap25 PE=1 SV=2	9031.ENSGALP00000000183	Rho GTPase activating protein 25 	_	KOG4270	_	PF00620.24|RhoGAP|RhoGAP domain|ENSGALT00000049938|m.4499:177-324;PF00169.26|PH|PH domain|ENSGALT00000049938|m.4499:46-149
ENSGALG00000035244	71.03882705	18.73819199	1.922059358	3.44E-96	3.88E-94	up	yes	62.91342363	70.8971421	79.30591542	19.67113404	17.75056887	18.79287307	1	48117646	48118846	+	ENSGALG00000035244	protein_coding	GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006334|nucleosome assembly	GO:0000786|nucleosome; GO:0005634|nucleus	GO:0031492|nucleosomal DNA binding; GO:0046982|protein heterodimerization activity	ko:K11253|H3	ko05034|Alcoholism; ko05202|Transcriptional misregulation in cancer; ko05322|Systemic lupus erythematosus	1201	XP_015714064.1	XP_015714064.1 PREDICTED: uncharacterized protein LOC107311753 [Coturnix japonica]	sp|P84227|H32_BOVIN	sp|P84227|H32_BOVIN Histone H3.2 OS=Bos taurus PE=1 SV=2	59729.ENSTGUP00000009617	annotation not avaliable	COG2036	KOG1745	_	PF00125.21|Histone|Core histone H2A/H2B/H3/H4|ENSGALT00000056622|m.1188:1-132
ENSGALG00000035266	0.343866475	0.717527791	-1.03979727	0.012935796	0.022386598	down	yes	0.546223804	0.128729497	0.356646125	0.667748556	0.802395353	0.682439465	1	127043815	127168755	+	ANOS1	protein_coding	GO:0007155|cell adhesion	GO:0005576|extracellular region; GO:0009986|cell surface	GO:0004867|serine-type endopeptidase inhibitor activity	--	--	2568	P33005.2	P33005.2 RecName: Full=Anosmin-1; AltName: Full=Kallmann syndrome protein homolog; Flags: Precursor	sp|P33005|KALM_CHICK	sp|P33005|KALM_CHICK Anosmin-1 OS=Gallus gallus GN=ANOS1 PE=2 SV=2	_	_	_	_	_	PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000076296|m.3527:182-266;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000076296|m.3527:293-372;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000076296|m.3527:545-640;PF00095.18|WAP|WAP-type (Whey Acidic Protein) 'four-disulfide core'|ENSGALT00000076296|m.3527:124-169
ENSGALG00000035334	13676.25747	3591.449805	1.929032269	2.27E-30	3.64E-29	up	yes	16630.42337	12697.74148	11700.60757	3763.257506	3592.730349	3418.361558	MT	9923	10706	+	COX3	protein_coding	GO:0019646|aerobic electron transport chain	GO:0005743|mitochondrial inner membrane; GO:0016021|integral component of membrane; GO:0045277|respiratory chain complex IV	GO:0004129|cytochrome-c oxidase activity	ko:K02262|COX3	ko00190|Oxidative phosphorylation; ko01100|Metabolic pathways; ko04260|Cardiac muscle contraction; ko04932|Non-alcoholic fatty liver disease (NAFLD); ko05010|Alzheimer's disease; ko05012|Parkinson's disease; ko05016|Huntington's disease	784	YP_002456301.1	YP_002456301.1 cytochrome c oxidase subunit III (mitochondrion) [Francolinus pintadeanus]	sp|Q8SEW8|COX3_COTJA	sp|Q8SEW8|COX3_COTJA Cytochrome c oxidase subunit 3 OS=Coturnix japonica GN=MT-CO3 PE=3 SV=1	_	_	_	_	_	_
ENSGALG00000035362	0.464871683	0.159107232	1.489599371	0.000163266	0.000388031	up	yes	0.44740129	0.431131734	0.516082026	0.091356986	0.171889987	0.214074723	21	4404710	4414378	+	ENSGALG00000035362	protein_coding	--	--	--	ko:K16469|CROCC	--	3886	XP_015152498.1	XP_015152498.1 rootletin isoform X1 [Gallus gallus]	_	_	_	_	_	_	_	_
ENSGALG00000035490	75.63347227	29.50586104	1.35772516	2.30E-56	1.01E-54	up	yes	77.36263536	76.1850439	73.35273755	33.3126168	27.83805533	27.36691098	5	56465775	56474283	-	MAPK1IP1L	protein_coding	--	--	--	--	--	1322	XP_004936539.2	XP_004936539.2 MAPK-interacting and spindle-stabilizing protein-like isoform X1 [Gallus gallus]	_	_	_	_	_	_	_	PF15822.2|MISS|MAPK-interacting and spindle-stabilising protein-like|ENSGALT00000069158|m.4105:45-285
ENSGALG00000035498	0.373027606	1.810696748	-2.248970369	3.34E-17	2.62E-16	down	yes	0.291195664	0.325875921	0.502011233	1.954294346	1.618396903	1.859398995	9	1294733	1337979	+	INPP5D	protein_coding	GO:0006661|phosphatidylinositol biosynthetic process; GO:0006796|phosphate-containing compound metabolic process; GO:0006915|apoptotic process; GO:0007165|signal transduction; GO:0008340|determination of adult lifespan; GO:0009968|negative regulation of signal transduction; GO:0016064|immunoglobulin mediated immune response; GO:0030889|negative regulation of B cell proliferation; GO:0035556|intracellular signal transduction; GO:0043065|positive regulation of apoptotic process; GO:0043647|inositol phosphate metabolic process; GO:0045409|negative regulation of interleukin-6 biosynthetic process; GO:0045579|positive regulation of B cell differentiation; GO:0045648|positive regulation of erythrocyte differentiation; GO:0045656|negative regulation of monocyte differentiation; GO:0045659|negative regulation of neutrophil differentiation; GO:0045671|negative regulation of osteoclast differentiation; GO:0045779|negative regulation of bone resorption; GO:0046856|phosphatidylinositol dephosphorylation; GO:0050777|negative regulation of immune response; GO:0050852|T cell receptor signaling pathway; GO:0050900|leukocyte migration	GO:0005829|cytosol; GO:0005856|cytoskeleton; GO:0005886|plasma membrane; GO:0045121|membrane raft	"GO:0004445|inositol-polyphosphate 5-phosphatase activity; GO:0016314|phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; GO:0017124|SH3 domain binding; GO:0034485|phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity; GO:0051425|PTB domain binding; GO:0052659|inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity"	"ko:K03084|SHIP1,INPP5D"	ko00562|Inositol phosphate metabolism; ko04070|Phosphatidylinositol signaling system; ko04662|B cell receptor signaling pathway; ko04664|Fc epsilon RI signaling pathway; ko04666|Fc gamma R-mediated phagocytosis	3438	XP_025009298.1	"XP_025009298.1 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X2 [Gallus gallus]"	sp|Q92835|SHIP1_HUMAN	"sp|Q92835|SHIP1_HUMAN Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 OS=Homo sapiens GN=INPP5D PE=1 SV=2"	9031.ENSGALP00000040503	"inositol polyphosphate-5-phosphatase, 145kDa"	COG5411	KOG0565	_	PF03372.20|Exo_endo_phos|Endonuclease/Exonuclease/phosphatase family|ENSGALT00000082983|m.8268:408-700;PF00017.21|SH2|SH2 domain|ENSGALT00000082983|m.8268:5-86
ENSGALG00000035563	12.43756967	26.71827833	-1.102502821	5.14E-48	1.75E-46	down	yes	13.17546554	12.37745853	11.75978493	24.89310106	27.75426567	27.50746827	1	6569105	6679372	-	USP6NL	protein_coding	"GO:0006886|intracellular protein transport; GO:0007030|Golgi organization; GO:0019068|virion assembly; GO:0031338|regulation of vesicle fusion; GO:0035526|retrograde transport, plasma membrane to Golgi; GO:0043547|positive regulation of GTPase activity; GO:0048227|plasma membrane to endosome transport; GO:0090630|activation of GTPase activity; GO:1903358|regulation of Golgi organization"	GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0012505|endomembrane system; GO:0031410|cytoplasmic vesicle; GO:0032588|trans-Golgi network membrane	GO:0005096|GTPase activator activity; GO:0017137|Rab GTPase binding	ko:K20133|USP6NL	--	4834	XP_015151455.1	XP_015151455.1 USP6 N-terminal-like protein isoform X6 [Gallus gallus]	sp|Q92738|US6NL_HUMAN	sp|Q92738|US6NL_HUMAN USP6 N-terminal-like protein OS=Homo sapiens GN=USP6NL PE=1 SV=3	9031.ENSGALP00000010831	hypothetical protein LOC419104 	COG5210	KOG1102	_	PF00566.15|RabGAP-TBC|Rab-GTPase-TBC domain|ENSGALT00000071983|m.306:106-314
ENSGALG00000035569	0.505334943	0.014514597	4.393797478	2.93E-07	9.93E-07	up	yes	0.145475122	0.661307411	0.709222295	0.021888081	0	0.021655709	2	96511484	96522203	+	MC2R	protein_coding	GO:0001890|placenta development	GO:0005737|cytoplasm; GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0004978|corticotropin receptor activity	ko:K04200|MC2R	ko04024|cAMP signaling pathway; ko04080|Neuroactive ligand-receptor interaction; ko04925|Aldosterone synthesis and secretion	1811	XP_015137955.1	XP_015137955.1 adrenocorticotropic hormone receptor isoform X1 [Gallus gallus]	sp|Q64326|ACTHR_MOUSE	sp|Q64326|ACTHR_MOUSE Adrenocorticotropic hormone receptor OS=Mus musculus GN=Mc2r PE=3 SV=1	9031.ENSGALP00000022481	melanocortin 2 receptor 	_	KOG3656	_	PF00001.18|7tm_1|7 transmembrane receptor (rhodopsin family)|ENSGALT00000092949|m.1460:56-297;PF10320.6|7TM_GPCR_Srsx|Serpentine type 7TM GPCR chemoreceptor Srsx|ENSGALT00000092949|m.1460:53-312
ENSGALG00000035580	2.697998244	8.274119401	-1.613121544	5.53E-26	7.23E-25	down	yes	3.177235567	2.125503537	2.791255627	8.391950137	7.851363548	8.57904452	27	8012005	8018369	-	MPP2	protein_coding	GO:0051260|protein homooligomerization; GO:0060079|excitatory postsynaptic potential; GO:0060291|long-term synaptic potentiation	GO:0005737|cytoplasm; GO:0005856|cytoskeleton; GO:0014069|postsynaptic density; GO:0030054|cell junction; GO:0032590|dendrite membrane; GO:0032591|dendritic spine membrane; GO:0043197|dendritic spine; GO:0043198|dendritic shaft; GO:0045211|postsynaptic membrane	GO:0030165|PDZ domain binding; GO:0044325|ion channel binding	--	--	2272	XP_015155105.1	XP_015155105.1 MAGUK p55 subfamily member 2 isoform X4 [Gallus gallus]	sp|D3ZAA9|MPP2_RAT	sp|D3ZAA9|MPP2_RAT MAGUK p55 subfamily member 2 OS=Rattus norvegicus GN=Mpp2 PE=1 SV=2	_	_	_	_	_	PF00625.18|Guanylate_kin|Guanylate kinase|ENSGALT00000074108|m.9518:370-558;PF02828.13|L27|L27 domain|ENSGALT00000074108|m.9518:32-82;PF02828.13|L27|L27 domain|ENSGALT00000074108|m.9518:87-139;PF07653.14|SH3_2|Variant SH3 domain|ENSGALT00000074108|m.9518:248-309;PF00595.21|PDZ|PDZ domain (Also known as DHR or GLGF)|ENSGALT00000074108|m.9518:166-213;PF00018.25|SH3_1|SH3 domain|ENSGALT00000074108|m.9518:270-304
ENSGALG00000035599	11.92242578	4.713177929	1.337057573	1.74E-24	2.12E-23	up	yes	13.58281966	10.84208603	11.34237166	4.453639036	5.260462114	4.425432637	3	68013742	68017684	+	CD24	protein_coding	--	--	--	ko:K06469|CD24	ko04640|Hematopoietic cell lineage	2056	NP_001264664.1	NP_001264664.1 signal transducer CD24 precursor [Gallus gallus]	_	_	_	_	_	_	_	_
ENSGALG00000035669	38.27610042	18.18891012	1.07296867	3.77E-58	1.74E-56	up	yes	37.4564916	38.70513954	38.66667013	18.15776094	17.40261772	19.00635169	2	56051752	56063679	-	ADNP2	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated; GO:0030182|neuron differentiation; GO:0030307|positive regulation of cell growth; GO:0034599|cellular response to oxidative stress; GO:0060548|negative regulation of cell death; GO:0071300|cellular response to retinoic acid"	GO:0005634|nucleus	GO:0003677|DNA binding; GO:0046872|metal ion binding	--	--	3180	XP_418898.1	XP_418898.1 activity-dependent neuroprotector homeobox protein 2 isoform X1 [Gallus gallus]	sp|Q6IQ32|ADNP2_HUMAN	sp|Q6IQ32|ADNP2_HUMAN Activity-dependent neuroprotector homeobox protein 2 OS=Homo sapiens GN=ADNP2 PE=1 SV=1	_	_	_	_	_	_
ENSGALG00000035717	18.41702247	7.694172256	1.258111106	4.56E-33	8.42E-32	up	yes	18.94530908	17.7517668	18.55399153	5.975617666	8.14746037	8.959438732	21	6542875	6568734	+	HSPG2	protein_coding	GO:0001523|retinoid metabolic process; GO:0001525|angiogenesis; GO:0006024|glycosaminoglycan biosynthetic process; GO:0006027|glycosaminoglycan catabolic process; GO:0006629|lipid metabolic process; GO:0006898|receptor-mediated endocytosis; GO:0006954|inflammatory response; GO:0007420|brain development; GO:0016049|cell growth; GO:0016525|negative regulation of angiogenesis; GO:0022617|extracellular matrix disassembly; GO:0030154|cell differentiation; GO:0030198|extracellular matrix organization; GO:0030203|glycosaminoglycan metabolic process; GO:0044267|cellular protein metabolic process; GO:0060548|negative regulation of cell death; GO:0072358|cardiovascular system development; GO:1905907|negative regulation of amyloid fibril formation	GO:0005576|extracellular region; GO:0005604|basement membrane; GO:0005615|extracellular space; GO:0005796|Golgi lumen; GO:0005886|plasma membrane; GO:0005925|focal adhesion; GO:0031012|extracellular matrix; GO:0043202|lysosomal lumen; GO:0070062|extracellular exosome; GO:0098797|plasma membrane protein complex	GO:0005178|integrin binding; GO:0005509|calcium ion binding; GO:0008022|protein C-terminus binding; GO:0050750|low-density lipoprotein particle receptor binding	ko:K06255|HSPG2	ko04512|ECM-receptor interaction; ko05161|Hepatitis B; ko05205|Proteoglycans in cancer	11847	XP_015152746.2	XP_015152746.2 LOW QUALITY PROTEIN: basement membrane-specific heparan sulfate proteoglycan core protein [Gallus gallus]	sp|P98160|PGBM_HUMAN	sp|P98160|PGBM_HUMAN Basement membrane-specific heparan sulfate proteoglycan core protein OS=Homo sapiens GN=HSPG2 PE=1 SV=4	9796.ENSECAP00000012479	heparan sulfate proteoglycan 2	_	KOG3509	_	PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000080452|m.4360:120-200;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000080452|m.4360:1390-1471;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000080452|m.4360:1487-1565;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000080452|m.4360:1595-1671;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000080452|m.4360:1679-1765;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000080452|m.4360:1774-1854;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000080452|m.4360:1877-1954;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000080452|m.4360:1973-2051;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000080452|m.4360:2069-2148;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000080452|m.4360:2164-2243;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000080452|m.4360:2261-2342;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000080452|m.4360:2361-2438;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000080452|m.4360:2454-2536;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000080452|m.4360:2550-2636;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000080452|m.4360:2646-2729;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000080452|m.4360:2742-2821;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000080452|m.4360:2826-2908;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000080452|m.4360:2926-3002;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000080452|m.4360:3016-3091;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000080452|m.4360:3095-3178;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000080452|m.4360:119-197;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000080452|m.4360:1388-1458;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000080452|m.4360:1481-1552;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000080452|m.4360:1593-1659;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000080452|m.4360:1679-1750;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000080452|m.4360:1772-1840;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000080452|m.4360:1875-1940;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000080452|m.4360:1973-2037;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000080452|m.4360:2069-2134;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000080452|m.4360:2162-2231;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000080452|m.4360:2259-2328;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000080452|m.4360:2361-2425;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000080452|m.4360:2453-2521;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000080452|m.4360:2549-2623;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000080452|m.4360:2640-2715;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000080452|m.4360:2739-2807;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000080452|m.4360:2824-2895;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000080452|m.4360:3016-3078;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000080452|m.4360:3095-3165;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000080452|m.4360:124-200;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000080452|m.4360:1391-1466;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000080452|m.4360:1486-1552;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000080452|m.4360:1681-1765;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000080452|m.4360:1775-1854;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000080452|m.4360:1875-1954;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000080452|m.4360:1971-2051;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000080452|m.4360:2069-2148;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000080452|m.4360:2166-2244;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000080452|m.4360:2263-2342;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000080452|m.4360:2360-2439;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000080452|m.4360:2457-2533;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000080452|m.4360:2739-2811;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000080452|m.4360:2831-2903;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000080452|m.4360:3014-3087;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000080452|m.4360:3101-3171;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000080452|m.4360:127-200;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000080452|m.4360:1391-1467;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000080452|m.4360:1487-1554;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000080452|m.4360:1685-1753;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000080452|m.4360:1777-1851;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000080452|m.4360:1878-1940;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000080452|m.4360:1974-2037;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000080452|m.4360:2070-2134;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000080452|m.4360:2168-2238;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000080452|m.4360:2265-2328;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000080452|m.4360:2362-2430;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000080452|m.4360:2462-2522;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000080452|m.4360:2647-2725;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000080452|m.4360:2743-2818;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000080452|m.4360:2834-2903;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000080452|m.4360:3017-3087;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000080452|m.4360:3105-3173;PF00052.15|Laminin_B|Laminin B (Domain IV)|ENSGALT00000080452|m.4360:309-442;PF00052.15|Laminin_B|Laminin B (Domain IV)|ENSGALT00000080452|m.4360:703-837;PF00052.15|Laminin_B|Laminin B (Domain IV)|ENSGALT00000080452|m.4360:1104-1236;PF00054.20|Laminin_G_1|Laminin G domain|ENSGALT00000080452|m.4360:3212-3340;PF00054.20|Laminin_G_1|Laminin G domain|ENSGALT00000080452|m.4360:3471-3595;PF00054.20|Laminin_G_1|Laminin G domain|ENSGALT00000080452|m.4360:3798-3920;PF02210.21|Laminin_G_2|Laminin G domain|ENSGALT00000080452|m.4360:3212-3338;PF02210.21|Laminin_G_2|Laminin G domain|ENSGALT00000080452|m.4360:3468-3592;PF02210.21|Laminin_G_2|Laminin G domain|ENSGALT00000080452|m.4360:3797-3921;PF00053.21|Laminin_EGF|Laminin EGF domain|ENSGALT00000080452|m.4360:477-519;PF00053.21|Laminin_EGF|Laminin EGF domain|ENSGALT00000080452|m.4360:527-582;PF00053.21|Laminin_EGF|Laminin EGF domain|ENSGALT00000080452|m.4360:582-634;PF00053.21|Laminin_EGF|Laminin EGF domain|ENSGALT00000080452|m.4360:872-919;PF00053.21|Laminin_EGF|Laminin EGF domain|ENSGALT00000080452|m.4360:922-968;PF00053.21|Laminin_EGF|Laminin EGF domain|ENSGALT00000080452|m.4360:983-1030;PF00053.21|Laminin_EGF|Laminin EGF domain|ENSGALT00000080452|m.4360:1237-1258;PF00053.21|Laminin_EGF|Laminin EGF domain|ENSGALT00000080452|m.4360:1271-1318;PF00053.21|Laminin_EGF|Laminin EGF domain|ENSGALT00000080452|m.4360:1321-1376;PF00057.15|Ldl_recept_a|Low-density lipoprotein receptor domain class A|ENSGALT00000080452|m.4360:38-73;PF00057.15|Ldl_recept_a|Low-density lipoprotein receptor domain class A|ENSGALT00000080452|m.4360:81-117;PF00008.24|EGF|EGF-like domain|ENSGALT00000080452|m.4360:3359-3390;PF00008.24|EGF|EGF-like domain|ENSGALT00000080452|m.4360:3615-3648;PF00008.24|EGF|EGF-like domain|ENSGALT00000080452|m.4360:3711-3738
ENSGALG00000035725	1.629304827	9.597939159	-2.551142869	2.51E-37	5.64E-36	down	yes	1.85881942	1.416863776	1.612231284	7.621880241	13.48029151	7.691645723	2	30161118	30163980	-	SP8	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006357|regulation of transcription by RNA polymerase II; GO:0030326|embryonic limb morphogenesis"	GO:0005634|nucleus	"GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0003677|DNA binding; GO:0046872|metal ion binding"	ko:K09198|SP8	--	2863	NP_001185595.1	NP_001185595.1 transcription factor Sp8 [Gallus gallus]	sp|Q64HY5|SP8_CHICK	sp|Q64HY5|SP8_CHICK Transcription factor Sp8 OS=Gallus gallus GN=SP8 PE=2 SV=1	_	_	_	_	_	"PF00096.23|zf-C2H2|Zinc finger, C2H2 type|ENSGALT00000048259|m.166:372-396;PF13894.3|zf-C2H2_4|C2H2-type zinc finger|ENSGALT00000048259|m.166:372-396;PF13894.3|zf-C2H2_4|C2H2-type zinc finger|ENSGALT00000048259|m.166:402-424"
ENSGALG00000035749	2.093050144	0.904411957	1.201567075	0.001034858	0.002175399	up	yes	2.172828417	1.991399603	2.114922413	0.998928911	0.883216411	0.831090551	10	1298372	1306712	-	ENSGALG00000035749	protein_coding	--	GO:0005654|nucleoplasm; GO:0005813|centrosome; GO:0005815|microtubule organizing center; GO:0005819|spindle; GO:0005829|cytosol; GO:0008274|gamma-tubulin ring complex	--	ko:K16574|MZT2A_B	--	613	XP_025009736.1	XP_025009736.1 mitotic-spindle organizing protein 2 isoform X1 [Gallus gallus]	sp|Q9CQ25|MZT2_MOUSE	sp|Q9CQ25|MZT2_MOUSE Mitotic-spindle organizing protein 2 OS=Mus musculus GN=Mzt2 PE=1 SV=1	9031.ENSGALP00000004000	similar to LOC653784 protein	_	_	NOG42386	PF12926.4|MOZART2|Mitotic-spindle organizing gamma-tubulin ring associated|ENSGALT00000106745|m.5076:20-89
ENSGALG00000035752	26.16020533	6.600132987	1.985174042	2.70E-114	4.95E-112	up	yes	24.01494307	26.2492323	28.21644062	6.453221882	6.995443958	6.35173312	2	119484870	119507975	-	PEX2	protein_coding	GO:0000038|very long-chain fatty acid metabolic process; GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006635|fatty acid beta-oxidation; GO:0007031|peroxisome organization; GO:0016558|protein import into peroxisome matrix; GO:0016567|protein ubiquitination; GO:0031648|protein destabilization; GO:0048147|negative regulation of fibroblast proliferation; GO:0050680|negative regulation of epithelial cell proliferation	GO:0005778|peroxisomal membrane; GO:0005779|integral component of peroxisomal membrane; GO:0016020|membrane; GO:0016593|Cdc73/Paf1 complex	GO:0046872|metal ion binding; GO:0061630|ubiquitin protein ligase activity	"ko:K06664|PEX2,PXMP3"	ko04146|Peroxisome	2973	NP_001008454.1	NP_001008454.1 peroxisome biogenesis factor 2 [Gallus gallus]	sp|P28328|PEX2_HUMAN	sp|P28328|PEX2_HUMAN Peroxisome biogenesis factor 2 OS=Homo sapiens GN=PEX2 PE=1 SV=2	9031.ENSGALP00000025244	peroxisomal membrane protein 3 	_	KOG2879	_	"PF04757.11|Pex2_Pex12|Pex2 / Pex12 amino terminal region|ENSGALT00000073047|m.1965:28-224;PF00097.22|zf-C3HC4|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000073047|m.1965:244-283"
ENSGALG00000035760	7.398874694	1.203913995	2.609588222	2.50E-53	1.02E-51	up	yes	7.818253869	6.470972724	7.907397487	1.05441238	1.074003537	1.483326068	KZ626836.1	51829	59253	+	LENG8	protein_coding	--	--	--	--	--	2406	XP_025002064.1	XP_025002064.1 LOW QUALITY PROTEIN: leukocyte receptor cluster member 8 homolog [Gallus gallus]	sp|Q32NW2|LENG8_XENLA	sp|Q32NW2|LENG8_XENLA Leukocyte receptor cluster member 8 homolog OS=Xenopus laevis GN=leng8 PE=2 SV=1	_	_	_	_	_	PF03399.13|SAC3_GANP|SAC3/GANP family|ENSGALT00000052231|m.9736:569-777
ENSGALG00000035761	0.793567532	0.177232281	2.101590083	2.05E-06	6.30E-06	up	yes	0.913718308	0.558282548	0.908701742	0.143205619	0.180686126	0.207805097	2	22635251	22646949	-	ENSGALG00000035761	protein_coding	GO:0009058|biosynthetic process	--	GO:0003824|catalytic activity; GO:0030170|pyridoxal phosphate binding; GO:0042802|identical protein binding	--	--	1949	XP_015137431.1	XP_015137431.1 1-aminocyclopropane-1-carboxylate synthase-like protein 1 isoform X4 [Gallus gallus]	sp|A2AIG8|1A1L1_MOUSE	sp|A2AIG8|1A1L1_MOUSE 1-aminocyclopropane-1-carboxylate synthase-like protein 1 OS=Mus musculus GN=Accs PE=2 SV=1	9031.ENSGALP00000015308	similar to 1-aminocyclopropane-1-carboxylate synthase	COG0436	KOG0256	_	PF00155.18|Aminotran_1_2|Aminotransferase class I and II|ENSGALT00000063330|m.15129:12-317
ENSGALG00000035854	0.585543375	1.269100119	-1.1028507	0.00094113	0.001989447	down	yes	0.409795617	0.85394606	0.492888448	1.362956404	1.023616856	1.420727097	2	41532339	41538738	+	ENSGALG00000035854	protein_coding	GO:0007155|cell adhesion	GO:0005576|extracellular region; GO:0005581|collagen trimer; GO:0031012|extracellular matrix	--	ko:K06238|COL6A	ko04151|PI3K-Akt signaling pathway; ko04510|Focal adhesion; ko04512|ECM-receptor interaction; ko04974|Protein digestion and absorption	2443	XP_015137249.1	XP_015137249.1 collagen alpha-6(VI) chain isoform X2 [Gallus gallus]	sp|Q8C6K9|CO6A6_MOUSE	sp|Q8C6K9|CO6A6_MOUSE Collagen alpha-6(VI) chain OS=Mus musculus GN=Col6a6 PE=1 SV=2	_	_	_	_	_	PF00092.25|VWA|von Willebrand factor type A domain|ENSGALT00000072280|m.487:117-296;PF00014.20|Kunitz_BPTI|Kunitz/Bovine pancreatic trypsin inhibitor domain|ENSGALT00000072280|m.487:442-493;PF13519.3|VWA_2|von Willebrand factor type A domain|ENSGALT00000072280|m.487:121-238
ENSGALG00000035879	8.693500828	3.179019126	1.448483066	3.99E-39	9.54E-38	up	yes	9.472878861	8.338849812	8.268773811	3.189556936	2.972138663	3.375361778	33	5470014	5483465	-	ITGA7	protein_coding	GO:0007160|cell-matrix adhesion; GO:0007229|integrin-mediated signaling pathway; GO:0007517|muscle organ development; GO:0008360|regulation of cell shape; GO:0030198|extracellular matrix organization; GO:0034113|heterotypic cell-cell adhesion; GO:0035987|endodermal cell differentiation	GO:0005886|plasma membrane; GO:0008305|integrin complex; GO:0009986|cell surface	GO:0046872|metal ion binding	ko:K06583|ITGA7	ko04151|PI3K-Akt signaling pathway; ko04510|Focal adhesion; ko04512|ECM-receptor interaction; ko04810|Regulation of actin cytoskeleton; ko05410|Hypertrophic cardiomyopathy (HCM); ko05412|Arrhythmogenic right ventricular cardiomyopathy (ARVC); ko05414|Dilated cardiomyopathy	3543	XP_015128074.1	XP_015128074.1 integrin alpha-7 isoform X1 [Gallus gallus]	sp|Q13683|ITA7_HUMAN	sp|Q13683|ITA7_HUMAN Integrin alpha-7 OS=Homo sapiens GN=ITGA7 PE=1 SV=3	9685.ENSFCAP00000012943	"integrin, alpha 7"	_	KOG3637	_	"PF08441.9|Integrin_alpha2|Integrin alpha|ENSGALT00000055830|m.15130:540-1021;PF01839.20|FG-GAP|FG-GAP repeat|ENSGALT00000055830|m.15130:389-427;PF01839.20|FG-GAP|FG-GAP repeat|ENSGALT00000055830|m.15130:450-483;PF13517.3|VCBS|Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella|ENSGALT00000055830|m.15130:397-470"
ENSGALG00000035911	14.95858869	44.7516061	-1.5803236	5.71E-91	5.90E-89	down	yes	14.12750186	15.53744495	15.21081924	43.52625917	46.78192895	43.94663017	18	9601368	9605211	+	CBX4	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006351|transcription, DNA-templated; GO:0016569|covalent chromatin modification; GO:0016925|protein sumoylation; GO:0045892|negative regulation of transcription, DNA-templated"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0016604|nuclear body; GO:0016607|nuclear speck; GO:0031519|PcG protein complex; GO:0035102|PRC1 complex	GO:0003682|chromatin binding; GO:0003727|single-stranded RNA binding; GO:0016874|ligase activity; GO:0019789|SUMO transferase activity; GO:0019899|enzyme binding; GO:0032183|SUMO binding; GO:0035064|methylated histone binding; GO:0044212|transcription regulatory region DNA binding; GO:0051219|phosphoprotein binding	"ko:K11452|CBX4,PC2"	--	2111	NP_989973.1	NP_989973.1 E3 SUMO-protein ligase CBX4 [Gallus gallus]	sp|O55187|CBX4_MOUSE	sp|O55187|CBX4_MOUSE E3 SUMO-protein ligase CBX4 OS=Mus musculus GN=Cbx4 PE=1 SV=2	59729.ENSTGUP00000003246	E3 SUMO-protein ligase CBX4 (Chromobox protein homolog 4)(Polycomb 2 homolog)(Pc2)(hPc2) [Ta [...] 	_	KOG2748	_	PF00385.21|Chromo|Chromo (CHRromatin Organisation MOdifier) domain|ENSGALT00000051639|m.13078:46-94
ENSGALG00000035935	0.024370097	0.507293739	-3.911757915	3.00E-08	1.13E-07	down	yes	0	0	0.07311029	0.385081388	0.702229441	0.434570388	10	8592962	8676758	-	ENSGALG00000035935	protein_coding	GO:0007268|chemical synaptic transmission; GO:0016082|synaptic vesicle priming; GO:0031914|negative regulation of synaptic plasticity; GO:0035556|intracellular signal transduction; GO:0046928|regulation of neurotransmitter secretion	GO:0005886|plasma membrane; GO:0030054|cell junction; GO:0030672|synaptic vesicle membrane; GO:0042734|presynaptic membrane; GO:0043195|terminal bouton; GO:0044305|calyx of Held; GO:0048786|presynaptic active zone; GO:0098793|presynapse	GO:0005516|calmodulin binding; GO:0017075|syntaxin-1 binding; GO:0019905|syntaxin binding; GO:0019992|diacylglycerol binding; GO:0046872|metal ion binding	"ko:K15293|UNC13A_B_C,MUNC13"	ko04721|Synaptic vesicle cycle	3294	XP_413798.5	XP_413798.5 LOW QUALITY PROTEIN: protein unc-13 homolog C [Gallus gallus]	sp|Q62770|UN13C_RAT	sp|Q62770|UN13C_RAT Protein unc-13 homolog C OS=Rattus norvegicus GN=Unc13c PE=1 SV=3	9031.ENSGALP00000007197	similar to Munc13-3	_	KOG1011	_	PF10540.6|Membr_traf_MHD|Munc13 (mammalian uncoordinated) homology domain|ENSGALT00000051879|m.5474:792-918;PF00168.27|C2|C2 domain|ENSGALT00000051879|m.5474:157-265;PF00168.27|C2|C2 domain|ENSGALT00000051879|m.5474:953-1054;PF06292.14|DUF1041|Domain of Unknown Function (DUF1041)|ENSGALT00000051879|m.5474:520-550;PF00130.19|C1_1|Phorbol esters/diacylglycerol binding domain (C1 domain)|ENSGALT00000051879|m.5474:34-83
ENSGALG00000035960	0.755254723	0.334310495	1.152229888	1.50E-06	4.70E-06	up	yes	0.60875456	0.781093901	0.875915709	0.343472887	0.297606362	0.361852235	KZ626838.1	225080	242676	+	ENSGALG00000035960	protein_coding	GO:0002026|regulation of the force of heart contraction; GO:0002027|regulation of heart rate; GO:0003009|skeletal muscle contraction; GO:0006936|muscle contraction; GO:0006941|striated muscle contraction; GO:0007512|adult heart development; GO:0014728|regulation of the force of skeletal muscle contraction; GO:0014883|transition between fast and slow fiber; GO:0014898|cardiac muscle hypertrophy in response to stress; GO:0030049|muscle filament sliding; GO:0031449|regulation of slow-twitch skeletal muscle fiber contraction; GO:0046034|ATP metabolic process; GO:0055010|ventricular cardiac muscle tissue morphogenesis; GO:0060048|cardiac muscle contraction	GO:0001725|stress fiber; GO:0005737|cytoplasm; GO:0016459|myosin complex; GO:0030016|myofibril; GO:0030017|sarcomere; GO:0030018|Z disc; GO:0032982|myosin filament	GO:0000146|microfilament motor activity; GO:0005516|calmodulin binding; GO:0005524|ATP binding; GO:0016887|ATPase activity; GO:0030898|actin-dependent ATPase activity; GO:0051015|actin filament binding	ko:K17751|MYH6_7	ko04260|Cardiac muscle contraction; ko04261|Adrenergic signaling in cardiomyocytes; ko05416|Viral myocarditis	6232	XP_025002170.1	XP_025002170.1 myosin-7 [Gallus gallus]	sp|Q91Z83|MYH7_MOUSE	sp|Q91Z83|MYH7_MOUSE Myosin-7 OS=Mus musculus GN=Myh7 PE=2 SV=1	59729.ENSTGUP00000008077	"Myosin-7 (Myosin heavy chain 7)(Myosin heavy chain, cardiac muscle beta isoform)(MyHC-beta)( [...] "	COG5022	KOG0161	_	PF00063.18|Myosin_head|Myosin head (motor domain)|ENSGALT00000047986|m.9914:12-608;PF00063.18|Myosin_head|Myosin head (motor domain)|ENSGALT00000047986|m.9914:697-745;PF01576.16|Myosin_tail_1|Myosin tail|ENSGALT00000047986|m.9914:825-1262;PF01576.16|Myosin_tail_1|Myosin tail|ENSGALT00000047986|m.9914:1303-1667
ENSGALG00000035993	2.46107571	1.035358952	1.241140799	0.000157888	0.000375914	up	yes	2.984680429	1.571137639	2.827409063	0.892388364	0.832354629	1.381333862	33	7079848	7081224	-	SUOX	protein_coding	GO:0006790|sulfur compound metabolic process; GO:0042128|nitrate assimilation	GO:0005758|mitochondrial intermembrane space	GO:0008482|sulfite oxidase activity; GO:0020037|heme binding; GO:0030151|molybdenum ion binding; GO:0043546|molybdopterin cofactor binding	ko:K00387|SUOX	ko00920|Sulfur metabolism; ko01100|Metabolic pathways; ko01120|Microbial metabolism in diverse environments	1377	XP_015155797.2	XP_015155797.2 sulfite oxidase isoform X2 [Gallus gallus]	sp|P07850|SUOX_CHICK	sp|P07850|SUOX_CHICK Sulfite oxidase OS=Gallus gallus GN=SUOX PE=1 SV=3	_	_	_	_	_	PF00174.16|Oxidored_molyb|Oxidoreductase molybdopterin binding domain|ENSGALT00000078009|m.15623:140-317;PF03404.13|Mo-co_dimer|Mo-co oxidoreductase dimerisation domain|ENSGALT00000078009|m.15623:341-459;PF00173.25|Cyt-b5|Cytochrome b5-like Heme/Steroid binding domain|ENSGALT00000078009|m.15623:8-82
ENSGALG00000036086	148.1275186	70.19545652	1.077282007	1.35E-31	2.34E-30	up	yes	150.5828674	143.6117998	150.1878886	78.92239513	60.37219458	71.29177986	25	3881435	3885725	+	TAGLN2	protein_coding	GO:0030855|epithelial cell differentiation	GO:0031982|vesicle; GO:0070062|extracellular exosome	GO:0045296|cadherin binding	--	--	612	XP_024999415.1	XP_024999415.1 protein turtle homolog A isoform X1 [Gallus gallus]	sp|Q9WVA4|TAGL2_MOUSE	sp|Q9WVA4|TAGL2_MOUSE Transgelin-2 OS=Mus musculus GN=Tagln2 PE=1 SV=4	_	_	_	_	_	PF00307.28|CH|Calponin homology (CH) domain|ENSGALT00000051520|m.7359:45-153
ENSGALG00000036133	3.601846542	7.488515461	-1.053868405	3.41E-13	1.98E-12	down	yes	2.774953909	4.44462912	3.585956596	7.909223905	7.39495258	7.161369899	12	11023383	11032726	-	KLF15	protein_coding	GO:0010001|glial cell differentiation; GO:0014898|cardiac muscle hypertrophy in response to stress; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0072112|glomerular visceral epithelial cell differentiation; GO:1901653|cellular response to peptide; GO:1904659|glucose transmembrane transport; GO:2000757|negative regulation of peptidyl-lysine acetylation	GO:0005634|nucleus	"GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0044212|transcription regulatory region DNA binding; GO:0046872|metal ion binding"	ko:K09210|KLF15	--	3190	XP_003210198.2	XP_003210198.2 PREDICTED: Krueppel-like factor 15 isoform X1 [Meleagris gallopavo]	sp|Q9UIH9|KLF15_HUMAN	sp|Q9UIH9|KLF15_HUMAN Krueppel-like factor 15 OS=Homo sapiens GN=KLF15 PE=1 SV=1	9031.ENSGALP00000010084	Kruppel-like factor 15	COG5048	KOG1721	_	"PF00096.23|zf-C2H2|Zinc finger, C2H2 type|ENSGALT00000079434|m.7725:368-390;PF13894.3|zf-C2H2_4|C2H2-type zinc finger|ENSGALT00000079434|m.7725:368-390"
ENSGALG00000036189	0.129053086	1.216042518	-3.14030134	0.004297781	0.008145897	down	yes	0	0.290972047	0.096187212	1.472394975	1.148613638	1.027118941	3	88592498	88638346	+	angiopoietin-2	protein_coding	GO:0001525|angiogenesis; GO:0001666|response to hypoxia; GO:0007165|signal transduction; GO:0007281|germ cell development; GO:0009314|response to radiation; GO:0009612|response to mechanical stimulus; GO:0009749|response to glucose; GO:0010812|negative regulation of cell-substrate adhesion; GO:0014070|response to organic cyclic compound; GO:0014823|response to activity; GO:0016525|negative regulation of angiogenesis; GO:0031100|animal organ regeneration; GO:0043537|negative regulation of blood vessel endothelial cell migration; GO:0045766|positive regulation of angiogenesis; GO:0048014|Tie signaling pathway; GO:0050900|leukocyte migration; GO:0050928|negative regulation of positive chemotaxis; GO:0060135|maternal process involved in female pregnancy; GO:0071363|cellular response to growth factor stimulus; GO:0072012|glomerulus vasculature development	GO:0005576|extracellular region; GO:0005615|extracellular space; GO:0005634|nucleus; GO:0005886|plasma membrane; GO:0042995|cell projection	GO:0005102|signaling receptor binding; GO:0030971|receptor tyrosine kinase binding; GO:0046872|metal ion binding	ko:K05466|ANGPT2	ko04014|Ras signaling pathway; ko04015|Rap1 signaling pathway; ko04066|HIF-1 signaling pathway; ko04151|PI3K-Akt signaling pathway	2581	CAC08175.1	CAC08175.1 angiopoietin-2B [Gallus gallus]	sp|O15123|ANGP2_HUMAN	sp|O15123|ANGP2_HUMAN Angiopoietin-2 OS=Homo sapiens GN=ANGPT2 PE=1 SV=1	9031.ENSGALP00000026291	Angiopoietin-2B (Ang-2B) 	_	KOG2579	_	"PF00147.15|Fibrinogen_C|Fibrinogen beta and gamma chains, C-terminal globular domain|ENSGALT00000060832|m.12859:193-404"
ENSGALG00000036229	3760.588684	1572.639782	1.257764928	5.60E-07	1.84E-06	up	yes	5004.621056	3420.155405	2856.989592	1545.933301	1562.647655	1609.33839	MT	11486	12863	+	ND4	protein_coding	"GO:0006120|mitochondrial electron transport, NADH to ubiquinone"	GO:0016021|integral component of membrane; GO:0031966|mitochondrial membrane; GO:0070469|respirasome	GO:0008137|NADH dehydrogenase (ubiquinone) activity	ko:K03881|ND4	ko00190|Oxidative phosphorylation; ko01100|Metabolic pathways; ko04723|Retrograde endocannabinoid signaling; ko05012|Parkinson's disease	1378	AMP87950.1	AMP87950.1 NADH dehydrogenase subunit 4 (mitochondrion) [Gallus gallus]	sp|P18939|NU4M_CHICK	sp|P18939|NU4M_CHICK NADH-ubiquinone oxidoreductase chain 4 OS=Gallus gallus GN=MT-ND4 PE=3 SV=1	9031.ENSGALP00000034621	NADH-ubiquinone oxidoreductase chain 4 (EC 1.6.5.3)(NADH dehydrogenase subunit 4); Core subu [...] 	COG1008	KOG4845	_	_
ENSGALG00000036244	1.724712394	0.381432085	2.147862571	3.76E-07	1.26E-06	up	yes	1.583993837	1.673761682	1.916381663	0.403052279	0.221104861	0.520139115	2	105465974	105467104	+	ENSGALG00000036244	protein_coding	--	GO:0016020|membrane; GO:0016021|integral component of membrane	--	--	--	1131	XP_025000011.1	"XP_025000011.1 inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 [Gallus gallus]"	sp|Q66H52|IPIL1_RAT	"sp|Q66H52|IPIL1_RAT Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 OS=Rattus norvegicus GN=Itpripl1 PE=2 SV=1"	9031.ENSGALP00000031820	"inositol 1,4,5-triphosphate receptor interacting protein-like 1"	_	_	NOG267113	_
ENSGALG00000036355	46.57414693	20.2213565	1.203246019	2.28E-27	3.20E-26	up	yes	44.62437514	50.77679789	44.32126776	21.43363634	19.14213534	20.08829782	1	58399989	58406158	-	STMP1	protein_coding	--	GO:0016021|integral component of membrane; GO:0031966|mitochondrial membrane	--	--	--	614	NP_001289062.1	NP_001289062.1 short transmembrane mitochondrial protein 1 [Gallus gallus]	sp|E0CX11|STMP1_HUMAN	sp|E0CX11|STMP1_HUMAN Short transmembrane mitochondrial protein 1 OS=Homo sapiens GN=STMP1 PE=1 SV=1	_	_	_	_	_	_
ENSGALG00000036391	95.67181959	47.39311855	1.013262851	3.87E-05	0.000100956	up	yes	92.16173607	97.39065071	97.46307199	54.2590026	31.22937244	56.69098062	22	254899	283905	+	GFPT1	protein_coding	GO:0006002|fructose 6-phosphate metabolic process; GO:0006047|UDP-N-acetylglucosamine metabolic process; GO:0006048|UDP-N-acetylglucosamine biosynthetic process; GO:0006112|energy reserve metabolic process; GO:0006487|protein N-linked glycosylation; GO:0006541|glutamine metabolic process; GO:0032922|circadian regulation of gene expression; GO:0036498|IRE1-mediated unfolded protein response	GO:0005829|cytosol; GO:0070062|extracellular exosome	GO:0004360|glutamine-fructose-6-phosphate transaminase (isomerizing) activity; GO:0097367|carbohydrate derivative binding	"ko:K00820|glmS,GFPT"	"ko00250|Alanine, aspartate and glutamate metabolism; ko00520|Amino sugar and nucleotide sugar metabolism; ko01100|Metabolic pathways; ko01130|Biosynthesis of antibiotics; ko04931|Insulin resistance"	4944	NP_001026053.1	NP_001026053.1 glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 [Gallus gallus]	sp|Q06210|GFPT1_HUMAN	sp|Q06210|GFPT1_HUMAN Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens GN=GFPT1 PE=1 SV=3	9031.ENSGALP00000000114	glucosamine-fructose-6-phosphate aminotransferase 	COG0449	KOG1268	_	PF01380.19|SIS|SIS domain|ENSGALT00000056244|m.4491:381-509;PF01380.19|SIS|SIS domain|ENSGALT00000056244|m.4491:551-681;PF13522.3|GATase_6|Glutamine amidotransferase domain|ENSGALT00000056244|m.4491:86-191;PF13537.3|GATase_7|Glutamine amidotransferase domain|ENSGALT00000056244|m.4491:109-189
ENSGALG00000036412	0.190622097	1.678646483	-3.073314914	0.007713801	0.013927953	down	yes	0.357747453	0	0.214118837	2.201116205	1.46540946	1.369413785	2	42447408	42553652	+	TMEM108	protein_coding	GO:0006898|receptor-mediated endocytosis; GO:0008090|retrograde axonal transport; GO:0021542|dentate gyrus development; GO:0031175|neuron projection development; GO:0051388|positive regulation of neurotrophin TRK receptor signaling pathway; GO:0097106|postsynaptic density organization; GO:0097484|dendrite extension; GO:0098815|modulation of excitatory postsynaptic potential; GO:1990416|cellular response to brain-derived neurotrophic factor stimulus	GO:0005769|early endosome; GO:0010008|endosome membrane; GO:0014069|postsynaptic density; GO:0016021|integral component of membrane; GO:0030054|cell junction; GO:0030424|axon; GO:0030425|dendrite; GO:0036477|somatodendritic compartment; GO:0045211|postsynaptic membrane; GO:1904115|axon cytoplasm	--	--	--	1865	XP_004939508.1	XP_004939508.1 transmembrane protein 108 isoform X1 [Gallus gallus]	sp|Q6UXF1|TM108_HUMAN	sp|Q6UXF1|TM108_HUMAN Transmembrane protein 108 OS=Homo sapiens GN=TMEM108 PE=2 SV=2	_	_	_	_	_	PF15759.2|TMEM108|TMEM108 family|ENSGALT00000085237|m.504:49-476
ENSGALG00000036447	2.851879257	1.047357353	1.436499762	1.94E-11	9.78E-11	up	yes	2.315428065	3.203436778	3.036772929	1.189027994	0.844076467	1.108967598	1	75760373	75776389	+	ENSGALG00000036447	protein_coding	GO:0052548|regulation of endopeptidase activity	GO:0005615|extracellular space; GO:0070062|extracellular exosome	GO:0004867|serine-type endopeptidase inhibitor activity; GO:0030414|peptidase inhibitor activity	--	--	2617	XP_025007673.1	XP_025007673.1 alpha-2-macroglobulin-like protein 1 [Gallus gallus]	sp|A8K2U0|A2ML1_HUMAN	sp|A8K2U0|A2ML1_HUMAN Alpha-2-macroglobulin-like protein 1 OS=Homo sapiens GN=A2ML1 PE=1 SV=3	59729.ENSTGUP00000013496	alpha-2-macroglobulin-like 1	_	KOG1366	_	PF00207.19|A2M|Alpha-2-macroglobulin family|ENSGALT00000069178|m.2275:707-796;PF07703.11|A2M_N_2|Alpha-2-macroglobulin family N-terminal region|ENSGALT00000069178|m.2275:432-576;PF01835.16|A2M_N|MG2 domain|ENSGALT00000069178|m.2275:101-182;PF05326.8|SVA|Seminal vesicle autoantigen (SVA)|ENSGALT00000069178|m.2275:758-832
ENSGALG00000036456	40.33464507	110.8132578	-1.457811579	5.09E-99	6.15E-97	down	yes	40.25994744	40.46296201	40.28102576	114.5785216	109.9315487	107.9297029	2	138859505	138862431	+	TRIB1	protein_coding	GO:0006469|negative regulation of protein kinase activity; GO:0007254|JNK cascade; GO:0014912|negative regulation of smooth muscle cell migration; GO:0031665|negative regulation of lipopolysaccharide-mediated signaling pathway; GO:0032436|positive regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0032496|response to lipopolysaccharide; GO:0043405|regulation of MAP kinase activity; GO:0043433|negative regulation of DNA-binding transcription factor activity; GO:0045645|positive regulation of eosinophil differentiation; GO:0045651|positive regulation of macrophage differentiation; GO:0045659|negative regulation of neutrophil differentiation; GO:0048662|negative regulation of smooth muscle cell proliferation	GO:0005634|nucleus; GO:0005737|cytoplasm	GO:0004860|protein kinase inhibitor activity; GO:0008134|transcription factor binding; GO:0031434|mitogen-activated protein kinase kinase binding; GO:0031625|ubiquitin protein ligase binding; GO:0055106|ubiquitin-protein transferase regulator activity	ko:K08814|TRIB1_2	--	1119	XP_015138631.1	XP_015138631.1 tribbles homolog 1 [Gallus gallus]	sp|Q96RU8|TRIB1_HUMAN	sp|Q96RU8|TRIB1_HUMAN Tribbles homolog 1 OS=Homo sapiens GN=TRIB1 PE=1 SV=2	13616.ENSMODP00000002132	tribbles homolog 1 (Drosophila)	COG0515	KOG0583	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000060923|m.2522:134-337;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000060923|m.2522:135-331;PF14531.3|Kinase-like|Kinase-like|ENSGALT00000060923|m.2522:163-325
ENSGALG00000036477	21.69672307	9.264111816	1.226860921	2.33E-44	7.04E-43	up	yes	21.79546116	22.21729867	21.07740936	10.11810731	8.302645801	9.371582334	2	154470	159009	-	CHPF2	protein_coding	GO:0030206|chondroitin sulfate biosynthetic process	GO:0000139|Golgi membrane; GO:0016020|membrane; GO:0016021|integral component of membrane; GO:0032580|Golgi cisterna membrane	GO:0008376|acetylgalactosaminyltransferase activity; GO:0050510|N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity	ko:K03419|CHPF2	ko00532|Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate; ko01100|Metabolic pathways	3283	XP_423717.3	XP_423717.3 chondroitin sulfate glucuronyltransferase [Gallus gallus]	sp|Q9P2E5|CHPF2_HUMAN	sp|Q9P2E5|CHPF2_HUMAN Chondroitin sulfate glucuronyltransferase OS=Homo sapiens GN=CHPF2 PE=2 SV=2	59729.ENSTGUP00000000042	microRNA 671	_	KOG3708	_	PF05679.13|CHGN|Chondroitin N-acetylgalactosaminyltransferase|ENSGALT00000085507|m.14298:245-747;PF02434.13|Fringe|Fringe-like|ENSGALT00000085507|m.14298:105-276
ENSGALG00000036550	0.189782105	0.513899444	-1.390862572	0.001505983	0.003085247	down	yes	0.166802604	0.176655287	0.225888424	0.529825531	0.5497485	0.462124302	33	3160563	3165510	-	ENSGALG00000036550	protein_coding	--	GO:0016021|integral component of membrane	GO:0004252|serine-type endopeptidase activity	--	--	2843	XP_424480.2	XP_424480.2 transmembrane protease serine 12 isoform X1 [Gallus gallus]	sp|Q86WS5|TMPSC_HUMAN	sp|Q86WS5|TMPSC_HUMAN Transmembrane protease serine 12 OS=Homo sapiens GN=TMPRSS12 PE=1 SV=2	9031.ENSGALP00000009799	"transmembrane protease, serine 12"	COG5640	KOG3627	_	PF00089.23|Trypsin|Trypsin|ENSGALT00000080658|m.14743:9-246;PF09342.8|DUF1986|Domain of unknown function (DUF1986)|ENSGALT00000080658|m.14743:20-139
ENSGALG00000036566	2.099629331	4.979487441	-1.241902084	2.30E-18	1.96E-17	down	yes	2.409805734	2.224610428	1.66447183	4.748263966	5.115957808	5.07424055	4	200826	216542	-	ENSGALG00000036566	protein_coding	GO:0007165|signal transduction; GO:0051056|regulation of small GTPase mediated signal transduction	GO:0005829|cytosol	GO:0005096|GTPase activator activity	ko:K20641|ARHGAP20	--	4220	XP_025006291.1	XP_025006291.1 rho GTPase-activating protein 20 isoform X1 [Gallus gallus]	sp|Q9P2F6|RHG20_HUMAN	sp|Q9P2F6|RHG20_HUMAN Rho GTPase-activating protein 20 OS=Homo sapiens GN=ARHGAP20 PE=1 SV=2	_	_	_	_	_	PF00620.24|RhoGAP|RhoGAP domain|ENSGALT00000064921|m.15864:343-487;PF00788.20|RA|Ras association (RalGDS/AF-6) domain|ENSGALT00000064921|m.15864:166-241
ENSGALG00000036587	2.264486383	4.878139404	-1.103744632	2.37E-07	8.10E-07	down	yes	2.368138836	2.170401814	2.254918498	4.985843979	3.78538561	5.863188621	8	6358451	6366057	-	LHX4	protein_coding	"GO:0001890|placenta development; GO:0006351|transcription, DNA-templated; GO:0008045|motor neuron axon guidance; GO:0009887|animal organ morphogenesis; GO:0021526|medial motor column neuron differentiation; GO:0043066|negative regulation of apoptotic process; GO:0045944|positive regulation of transcription by RNA polymerase II"	GO:0005622|intracellular; GO:0005634|nucleus	GO:0043565|sequence-specific DNA binding; GO:0046872|metal ion binding	ko:K09374|LHX3_4	--	1602	XP_015145978.2	XP_015145978.2 LIM/homeobox protein Lhx4 isoform X2 [Gallus gallus]	sp|P53776|LHX4_MOUSE	sp|P53776|LHX4_MOUSE LIM/homeobox protein Lhx4 OS=Mus musculus GN=Lhx4 PE=1 SV=4	_	_	_	_	_	PF00412.19|LIM|LIM domain|ENSGALT00000066312|m.7176:175-230;PF00412.19|LIM|LIM domain|ENSGALT00000066312|m.7176:234-291;PF00046.26|Homeobox|Homeobox domain|ENSGALT00000066312|m.7176:303-359
ENSGALG00000036598	1.63657872	6.282985217	-1.934273068	3.38E-18	2.84E-17	down	yes	1.482358005	1.613831596	1.813546557	6.403793921	6.360110545	6.085051186	1	69294587	69354684	-	SHISAL1	protein_coding	--	GO:0016021|integral component of membrane	--	--	--	1173	XP_015146583.1	XP_015146583.1 protein shisa-like-1 isoform X1 [Gallus gallus]	sp|Q3SXP7|K1644_HUMAN	sp|Q3SXP7|K1644_HUMAN Uncharacterized protein KIAA1644 OS=Homo sapiens GN=KIAA1644 PE=2 SV=2	9031.ENSGALP00000022931	annotation not avaliable	_	_	NOG26016	PF13908.3|Shisa|Wnt and FGF inhibitory regulator|ENSGALT00000090723|m.2122:31-75
ENSGALG00000036616	6.325866885	16.0799043	-1.344541815	4.27E-30	6.72E-29	down	yes	6.055825531	6.105187741	6.816587382	16.85026825	14.29549565	17.093949	26	2075202	2083441	-	NUAK2	protein_coding	GO:0006468|protein phosphorylation; GO:0006915|apoptotic process; GO:0030036|actin cytoskeleton organization; GO:0035556|intracellular signal transduction; GO:0042149|cellular response to glucose starvation; GO:0043066|negative regulation of apoptotic process	GO:0005634|nucleus; GO:0005737|cytoplasm	GO:0000287|magnesium ion binding; GO:0004674|protein serine/threonine kinase activity; GO:0005524|ATP binding	ko:K08800|NUAK	--	1949	XP_417962.3	XP_417962.3 NUAK family SNF1-like kinase 2 [Gallus gallus]	sp|Q9H093|NUAK2_HUMAN	sp|Q9H093|NUAK2_HUMAN NUAK family SNF1-like kinase 2 OS=Homo sapiens GN=NUAK2 PE=1 SV=1	9031.ENSGALP00000000960	"NUAK family, SNF1-like kinase, 2"	COG0515	KOG0611	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000054640|m.7945:48-298;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000054640|m.7945:49-293;PF14531.3|Kinase-like|Kinase-like|ENSGALT00000054640|m.7945:58-250;PF01163.19|RIO1|RIO1 family|ENSGALT00000054640|m.7945:89-190;PF06293.11|Kdo|Lipopolysaccharide kinase (Kdo/WaaP) family|ENSGALT00000054640|m.7945:78-186
ENSGALG00000036621	5.338299146	12.0373008	-1.17155788	5.88E-18	4.82E-17	down	yes	5.911186012	5.03152596	5.072185465	12.17803597	11.15182496	12.78204146	4	73496003	73506423	-	ZCCHC4	protein_coding	--	--	"GO:0003676|nucleic acid binding; GO:0008168|methyltransferase activity; GO:0008270|zinc ion binding; GO:0016746|transferase activity, transferring acyl groups"	--	--	1539	XP_420756.4	XP_420756.4 zinc finger CCHC domain-containing protein 4 [Gallus gallus]	sp|Q9H5U6|ZCHC4_HUMAN	sp|Q9H5U6|ZCHC4_HUMAN Zinc finger CCHC domain-containing protein 4 OS=Homo sapiens GN=ZCCHC4 PE=1 SV=3	9031.ENSGALP00000023186	"zinc finger, CCHC domain containing 4"	_	KOG4399	_	PF10237.6|N6-adenineMlase|Probable N6-adenine methyltransferase|ENSGALT00000078101|m.1267:164-296;PF06839.9|zf-GRF|GRF zinc finger|ENSGALT00000078101|m.1267:35-79
ENSGALG00000036678	25.99369323	10.72771032	1.27603015	4.63E-31	7.70E-30	up	yes	27.68514851	27.06503325	23.23089795	10.09023377	12.04823706	10.04466014	27	5959008	5971321	+	ETV4	protein_coding	GO:0030154|cell differentiation; GO:0045944|positive regulation of transcription by RNA polymerase II	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005730|nucleolus	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific"	ko:K15592|ETV4	ko05202|Transcriptional misregulation in cancer	1593	OXB71987.1	OXB71987.1 hypothetical protein H355_003251 [Colinus virginianus]	sp|P43268|ETV4_HUMAN	sp|P43268|ETV4_HUMAN ETS translocation variant 4 OS=Homo sapiens GN=ETV4 PE=1 SV=3	9031.ENSGALP00000030743	Ets domain protein Fragment 	_	KOG3806	_	PF04621.10|ETS_PEA3_N|PEA3 subfamily ETS-domain transcription factor N terminal domain|ENSGALT00000067966|m.9008:135-342;PF04621.10|ETS_PEA3_N|PEA3 subfamily ETS-domain transcription factor N terminal domain|ENSGALT00000067966|m.9008:342-386;PF00178.19|Ets|Ets-domain|ENSGALT00000067966|m.9008:389-468
ENSGALG00000036683	10.76930146	3.093852704	1.796131689	1.18E-26	1.59E-25	up	yes	11.85002917	10.9647619	9.493113313	2.779686433	3.458777287	3.043094393	27	6498559	6500829	-	PNPO	protein_coding	GO:0008615|pyridoxine biosynthetic process; GO:0042823|pyridoxal phosphate biosynthetic process	GO:0005654|nucleoplasm; GO:0005829|cytosol	GO:0004733|pyridoxamine-phosphate oxidase activity; GO:0010181|FMN binding	"ko:K00275|pdxH,PNPO"	ko00750|Vitamin B6 metabolism; ko01100|Metabolic pathways; ko01120|Microbial metabolism in diverse environments	1205	XP_015154965.1	"XP_015154965.1 pyridoxine-5'-phosphate oxidase, partial [Gallus gallus]"	sp|Q5E9K3|PNPO_BOVIN	sp|Q5E9K3|PNPO_BOVIN Pyridoxine-5'-phosphate oxidase OS=Bos taurus GN=PNPO PE=2 SV=1	_	_	_	_	_	PF10590.6|PNPOx_C|Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region|ENSGALT00000071072|m.9072:162-216;PF01243.17|Pyridox_oxidase|Pyridoxamine 5'-phosphate oxidase|ENSGALT00000071072|m.9072:79-109
ENSGALG00000036728	0.068683138	0.693021203	-3.159441797	8.40E-11	4.00E-10	down	yes	0	0.132131276	0.073918139	0.776934753	0.646939677	0.655189178	21	1044071	1242675	-	PRDM16	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006351|transcription, DNA-templated; GO:0022008|neurogenesis; GO:0030512|negative regulation of transforming growth factor beta receptor signaling pathway; GO:0030853|negative regulation of granulocyte differentiation; GO:0035019|somatic stem cell population maintenance; GO:0043457|regulation of cellular respiration; GO:0043586|tongue development; GO:0045892|negative regulation of transcription, DNA-templated; GO:0045893|positive regulation of transcription, DNA-templated; GO:0050872|white fat cell differentiation; GO:0050873|brown fat cell differentiation; GO:0060021|roof of mouth development; GO:0090336|positive regulation of brown fat cell differentiation"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005829|cytosol; GO:0016235|aggresome; GO:0017053|transcriptional repressor complex	GO:0003713|transcription coactivator activity; GO:0018024|histone-lysine N-methyltransferase activity; GO:0033613|activating transcription factor binding; GO:0043565|sequence-specific DNA binding; GO:0046332|SMAD binding; GO:0046872|metal ion binding	--	--	3801	XP_417551.3	XP_417551.3 PR domain zinc finger protein 16 isoform X3 [Gallus gallus]	sp|Q9HAZ2|PRD16_HUMAN	sp|Q9HAZ2|PRD16_HUMAN PR domain zinc finger protein 16 OS=Homo sapiens GN=PRDM16 PE=1 SV=3	9031.ENSGALP00000001588	PR domain containing 16	COG5048	KOG1721	NOG40641	"PF00096.23|zf-C2H2|Zinc finger, C2H2 type|ENSGALT00000105090|m.3841:334-357;PF00096.23|zf-C2H2|Zinc finger, C2H2 type|ENSGALT00000105090|m.3841:943-965;PF00096.23|zf-C2H2|Zinc finger, C2H2 type|ENSGALT00000105090|m.3841:971-994;PF13894.3|zf-C2H2_4|C2H2-type zinc finger|ENSGALT00000105090|m.3841:943-965;PF13912.3|zf-C2H2_6|C2H2-type zinc finger|ENSGALT00000105090|m.3841:943-966"
ENSGALG00000036738	18.73535099	9.160068155	1.031528477	9.10E-33	1.66E-31	up	yes	16.67420445	19.38842607	20.14342244	9.090389499	9.379100558	9.010714408	1	93596025	93648691	+	IGSF3	protein_coding	GO:0007166|cell surface receptor signaling pathway; GO:0032808|lacrimal gland development	GO:0005886|plasma membrane; GO:0009986|cell surface; GO:0016021|integral component of membrane	--	"ko:K06522|IGSF2_3,CD101"	--	3495	XP_025000390.1	XP_025000390.1 immunoglobulin superfamily member 3 isoform X3 [Gallus gallus]	sp|O75054|IGSF3_HUMAN	sp|O75054|IGSF3_HUMAN Immunoglobulin superfamily member 3 OS=Homo sapiens GN=IGSF3 PE=2 SV=3	9031.ENSGALP00000024898	"immunoglobulin superfamily, member 3"	_	KOG3509	_	PF07686.14|V-set|Immunoglobulin V-set domain|ENSGALT00000052654|m.2900:19-132;PF07686.14|V-set|Immunoglobulin V-set domain|ENSGALT00000052654|m.2900:143-243;PF07686.14|V-set|Immunoglobulin V-set domain|ENSGALT00000052654|m.2900:677-775;PF07686.14|V-set|Immunoglobulin V-set domain|ENSGALT00000052654|m.2900:812-917;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000052654|m.2900:139-239;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000052654|m.2900:810-912;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000052654|m.2900:813-912
ENSGALG00000036743	10.21031493	4.677185191	1.12464595	2.29E-28	3.33E-27	up	yes	11.05327424	9.333098235	10.24457231	4.010059526	5.040839191	4.980656856	1	50628618	50645593	-	MGAT3	protein_coding	GO:0006487|protein N-linked glycosylation	GO:0000139|Golgi membrane; GO:0016021|integral component of membrane	"GO:0003830|beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity"	ko:K00737|MGAT3	ko00510|N-Glycan biosynthesis; ko01100|Metabolic pathways	6445	XP_015140665.1	"XP_015140665.1 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase isoform X1 [Gallus gallus]"	sp|Q09327|MGAT3_HUMAN	"sp|Q09327|MGAT3_HUMAN Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase OS=Homo sapiens GN=MGAT3 PE=2 SV=3"	28377.ENSACAP00000007442	"mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase"	_	_	NOG85038	PF04724.10|Glyco_transf_17|Glycosyltransferase family 17|ENSGALT00000072351|m.1343:179-332
ENSGALG00000036751	11.86081952	3.305193853	1.840254399	6.12E-12	3.19E-11	up	yes	12.85458937	11.38464874	11.34322045	2.585172744	3.020164225	4.31024459	14	16007197	16010781	+	ENSGALG00000036751	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006351|transcription, DNA-templated; GO:0007049|cell cycle; GO:0030154|cell differentiation"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005829|cytosol	"GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0001227|DNA-binding transcription repressor activity, RNA polymerase II-specific; GO:0003714|transcription corepressor activity; GO:0043565|sequence-specific DNA binding"	--	--	414	XP_025011104.1	XP_025011104.1 ETS translocation variant 3-like protein [Gallus gallus]	sp|P50548|ERF_HUMAN	sp|P50548|ERF_HUMAN ETS domain-containing transcription factor ERF OS=Homo sapiens GN=ERF PE=1 SV=2	_	_	_	_	_	PF00178.19|Ets|Ets-domain|ENSGALT00000056250|m.10172:21-99;PF00447.14|HSF_DNA-bind|HSF-type DNA-binding|ENSGALT00000056250|m.10172:27-90
ENSGALG00000036775	3.074957468	22.45464177	-2.864333552	6.96E-271	1.20E-267	down	yes	3.12074345	2.936900888	3.167228066	23.16230131	22.69802297	21.50360104	Z	2630793	2878710	-	SETBP1	protein_coding	--	GO:0005634|nucleus; GO:0005829|cytosol; GO:0016604|nuclear body	GO:0003677|DNA binding	--	--	5538	XP_001233854.3	XP_001233854.3 SET-binding protein isoform X1 [Gallus gallus]	sp|Q9Y6X0|SETBP_HUMAN	sp|Q9Y6X0|SETBP_HUMAN SET-binding protein OS=Homo sapiens GN=SETBP1 PE=1 SV=3	9031.ENSGALP00000002563	SET binding protein 1	_	KOG1083	_	_
ENSGALG00000036787	167.7496708	65.35091206	1.359895915	5.18E-116	1.04E-113	up	yes	162.1841732	172.6042228	168.4606164	61.65069916	68.59665812	65.8053789	5	21812534	21884849	+	HSD17B12	protein_coding	GO:0006633|fatty acid biosynthetic process; GO:0006703|estrogen biosynthetic process	GO:0005789|endoplasmic reticulum membrane; GO:0016021|integral component of membrane	GO:0004303|estradiol 17-beta-dehydrogenase activity; GO:0102339|3-oxo-arachidoyl-CoA reductase activity; GO:0102340|3-oxo-behenoyl-CoA reductase activity; GO:0102341|3-oxo-lignoceroyl-CoA reductase activity; GO:0102342|3-oxo-cerotoyl-CoA reductase activity	"ko:K10251|HSD17B12,KAR,IFA38"	ko00062|Fatty acid elongation; ko00140|Steroid hormone biosynthesis; ko01040|Biosynthesis of unsaturated fatty acids; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko01212|Fatty acid metabolism	2948	XP_015142684.1	XP_015142684.1 very-long-chain 3-oxoacyl-CoA reductase [Gallus gallus]	sp|O57314|DHB12_ANAPL	sp|O57314|DHB12_ANAPL Very-long-chain 3-oxoacyl-CoA reductase OS=Anas platyrhynchos GN=HSD17B12 PE=2 SV=1	59729.ENSTGUP00000010538	Estradiol 17-beta-dehydrogenase 12 (EC 1.1.1.62)(17-beta-hydroxysteroid dehydrogenase 12)(17 [...] 	COG0300	KOG1014	_	PF00106.22|adh_short|short chain dehydrogenase|ENSGALT00000052146|m.2903:140-330;PF13561.3|adh_short_C2|Enoyl-(Acyl carrier protein) reductase|ENSGALT00000052146|m.2903:145-331
ENSGALG00000036792	0.842689525	0.362071127	1.196442094	0.002805547	0.005486231	up	yes	0.737306594	0.888118444	0.902643537	0.425909686	0.229115907	0.431187788	2	148883622	148885622	+	TIGD5	protein_coding	--	GO:0005634|nucleus	GO:0003677|DNA binding	--	--	2001	XP_004940149.2	XP_004940149.2 tigger transposable element-derived protein 5 [Gallus gallus]	sp|G3MY25|TIGD5_BOVIN	sp|G3MY25|TIGD5_BOVIN Tigger transposable element-derived protein 5 OS=Bos taurus GN=TIGD5 PE=3 SV=2	9031.ENSGALP00000030167	tigger transposable element derived 5	_	KOG3105	_	PF03184.16|DDE_1|DDE superfamily endonuclease|ENSGALT00000062186|m.2668:318-508;PF03221.13|HTH_Tnp_Tc5|Tc5 transposase DNA-binding domain|ENSGALT00000062186|m.2668:197-258;PF04218.10|CENP-B_N|CENP-B N-terminal DNA-binding domain|ENSGALT00000062186|m.2668:133-174
ENSGALG00000036806	5.085977372	2.140230413	1.244867608	1.29E-10	6.07E-10	up	yes	5.777807148	4.098153223	5.381971744	2.149688738	2.272682579	1.998319922	33	5499569	5507669	+	GDF11	protein_coding	GO:0001501|skeletal system development; GO:0001656|metanephros development; GO:0001657|ureteric bud development; GO:0008285|negative regulation of cell population proliferation; GO:0009887|animal organ morphogenesis; GO:0009952|anterior/posterior pattern specification; GO:0010862|positive regulation of pathway-restricted SMAD protein phosphorylation; GO:0021512|spinal cord anterior/posterior patterning; GO:0031016|pancreas development; GO:0042981|regulation of apoptotic process; GO:0043408|regulation of MAPK cascade; GO:0045596|negative regulation of cell differentiation; GO:0045665|negative regulation of neuron differentiation; GO:0048469|cell maturation; GO:0048593|camera-type eye morphogenesis; GO:0060021|roof of mouth development; GO:0060395|SMAD protein signal transduction	GO:0005615|extracellular space; GO:0032991|protein-containing complex	GO:0005125|cytokine activity; GO:0005160|transforming growth factor beta receptor binding; GO:0008083|growth factor activity	ko:K05497|GDF8_11	--	1678	XP_010725179.2	XP_010725179.2 PREDICTED: growth/differentiation factor 11 [Meleagris gallopavo]	sp|Q9Z217|GDF11_RAT	sp|Q9Z217|GDF11_RAT Growth/differentiation factor 11 OS=Rattus norvegicus GN=Gdf11 PE=2 SV=2	28377.ENSACAP00000015165	growth differentiation factor 11	_	KOG3900	_	PF00688.15|TGFb_propeptide|TGF-beta propeptide|ENSGALT00000074363|m.15157:33-250;PF00019.17|TGF_beta|Transforming growth factor beta like domain|ENSGALT00000074363|m.15157:273-367
ENSGALG00000036873	14.2170898	30.53699082	-1.102389683	6.64E-52	2.57E-50	down	yes	14.16997848	14.90607586	13.57521508	30.69142965	29.76382907	31.15571375	24	89438	130728	+	SIK2	protein_coding	GO:0006468|protein phosphorylation; GO:0008286|insulin receptor signaling pathway; GO:0035556|intracellular signal transduction; GO:0046626|regulation of insulin receptor signaling pathway; GO:0046777|protein autophosphorylation	GO:0005634|nucleus; GO:0005737|cytoplasm	GO:0000287|magnesium ion binding; GO:0004674|protein serine/threonine kinase activity; GO:0005524|ATP binding	ko:K16311|SIK2	ko04922|Glucagon signaling pathway	3135	XP_015153557.1	XP_015153557.1 serine/threonine-protein kinase SIK2 isoform X2 [Gallus gallus]	sp|Q8CFH6|SIK2_MOUSE	sp|Q8CFH6|SIK2_MOUSE Serine/threonine-protein kinase SIK2 OS=Mus musculus GN=Sik2 PE=1 SV=1	9031.ENSGALP00000000416	hypothetical LOC419703	COG0515	KOG0586	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000078547|m.5976:25-276;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000078547|m.5976:28-272;PF14531.3|Kinase-like|Kinase-like|ENSGALT00000078547|m.5976:112-264
ENSGALG00000036896	0.927412393	1.973704566	-1.081441407	4.55E-08	1.68E-07	down	yes	0.686745328	1.007044542	1.08844731	1.716564846	2.093988995	2.110559858	6	25152751	25192289	-	ENSGALG00000036896	protein_coding	--	GO:0042995|cell projection	--	--	--	4757	XP_015144200.1	XP_015144200.1 cilia- and flagella-associated protein 43 isoform X1 [Gallus gallus]	sp|Q8NDM7|CFA43_HUMAN	sp|Q8NDM7|CFA43_HUMAN Cilia- and flagella-associated protein 43 OS=Homo sapiens GN=CFAP43 PE=2 SV=3	_	_	_	_	_	_
ENSGALG00000036915	70.50112426	22.73084738	1.63256487	3.60E-152	1.45E-149	up	yes	69.50957609	68.89002361	73.10377308	22.38101479	23.11854009	22.69298725	2	138683095	138697225	+	SQLE	protein_coding	GO:0006695|cholesterol biosynthetic process; GO:0006725|cellular aromatic compound metabolic process; GO:0008203|cholesterol metabolic process; GO:0010033|response to organic substance; GO:0016126|sterol biosynthetic process; GO:0045540|regulation of cholesterol biosynthetic process	GO:0005783|endoplasmic reticulum; GO:0005789|endoplasmic reticulum membrane; GO:0016021|integral component of membrane; GO:0031090|organelle membrane	GO:0004506|squalene monooxygenase activity; GO:0050660|flavin adenine dinucleotide binding	"ko:K00511|SQLE,ERG1"	ko00100|Steroid biosynthesis; ko00909|Sesquiterpenoid and triterpenoid biosynthesis; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko01130|Biosynthesis of antibiotics	2569	NP_001181856.1	NP_001181856.1 squalene monooxygenase [Gallus gallus]	sp|Q14534|ERG1_HUMAN	sp|Q14534|ERG1_HUMAN Squalene monooxygenase OS=Homo sapiens GN=SQLE PE=1 SV=3	_	_	_	_	_	PF08491.7|SE|Squalene epoxidase|ENSGALT00000074439|m.2517:276-546;PF01494.16|FAD_binding_3|FAD binding domain|ENSGALT00000074439|m.2517:124-427
ENSGALG00000036962	211.0879787	97.65558698	1.11199055	4.96E-108	7.49E-106	up	yes	211.8172757	208.7050454	212.741615	95.52248958	97.83625003	99.60802133	27	6572282	6591811	-	KPNB1	protein_coding	GO:0006309|apoptotic DNA fragmentation; GO:0006606|protein import into nucleus; GO:0006607|NLS-bearing protein import into nucleus; GO:0006610|ribosomal protein import into nucleus; GO:0007079|mitotic chromosome movement towards spindle pole; GO:0007080|mitotic metaphase plate congression; GO:0019054|modulation by virus of host cellular process; GO:0030953|astral microtubule organization; GO:0031291|Ran protein signal transduction; GO:0040001|establishment of mitotic spindle localization; GO:0043312|neutrophil degranulation; GO:0045184|establishment of protein localization; GO:0045540|regulation of cholesterol biosynthetic process; GO:0075733|intracellular transport of virus; GO:0090307|mitotic spindle assembly	GO:0005576|extracellular region; GO:0005635|nuclear envelope; GO:0005643|nuclear pore; GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0016020|membrane; GO:0031965|nuclear membrane; GO:0034399|nuclear periphery; GO:0035580|specific granule lumen; GO:0043657|host cell; GO:0070062|extracellular exosome; GO:0071782|endoplasmic reticulum tubular network; GO:1904813|ficolin-1-rich granule lumen	GO:0003723|RNA binding; GO:0008139|nuclear localization sequence binding; GO:0008270|zinc ion binding; GO:0008536|Ran GTPase binding; GO:0019899|enzyme binding; GO:0019904|protein domain specific binding; GO:0051879|Hsp90 protein binding	"ko:K14293|KPNB1,IPO1"	ko03013|RNA transport	3503	XP_015154959.1	XP_015154959.1 importin subunit beta-1 [Gallus gallus]	sp|Q14974|IMB1_HUMAN	sp|Q14974|IMB1_HUMAN Importin subunit beta-1 OS=Homo sapiens GN=KPNB1 PE=1 SV=2	13616.ENSMODP00000015652	karyopherin (importin) beta 1	COG5215	KOG1241	_	PF02985.19|HEAT|HEAT repeat|ENSGALT00000075084|m.9105:410-437;PF13513.3|HEAT_EZ|HEAT-like repeat|ENSGALT00000075084|m.9105:380-435;PF03810.16|IBN_N|Importin-beta N-terminal domain|ENSGALT00000075084|m.9105:21-101
ENSGALG00000037065	12.72611555	4.157078703	1.611817076	3.27E-42	9.09E-41	up	yes	12.07730462	12.98392541	13.11711662	4.740371739	4.253761201	3.477103169	24	3559479	3564721	-	SC5D	protein_coding	GO:0033490|cholesterol biosynthetic process via lathosterol	GO:0005789|endoplasmic reticulum membrane; GO:0016021|integral component of membrane	GO:0000248|C-5 sterol desaturase activity; GO:0005506|iron ion binding; GO:0050046|lathosterol oxidase activity	"ko:K00227|SC5DL,ERG3"	ko00100|Steroid biosynthesis; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko01130|Biosynthesis of antibiotics	2897	XP_015153662.1	XP_015153662.1 lathosterol oxidase [Gallus gallus]	sp|O88822|SC5D_MOUSE	sp|O88822|SC5D_MOUSE Lathosterol oxidase OS=Mus musculus GN=Sc5d PE=2 SV=2	_	_	_	_	_	PF04116.10|FA_hydroxylase|Fatty acid hydroxylase superfamily|ENSGALT00000097483|m.6181:278-406
ENSGALG00000037160	2.611681189	12.12640026	-2.21077641	3.08E-34	5.98E-33	down	yes	1.838061248	2.554954113	3.442028208	12.28645932	11.97947262	12.11326884	Z	1243251	1267913	+	ENSGALG00000037160	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0001657|ureteric bud development; GO:0002725|negative regulation of T cell cytokine production; GO:0006351|transcription, DNA-templated; GO:0007179|transforming growth factor beta receptor signaling pathway; GO:0010717|regulation of epithelial to mesenchymal transition; GO:0010801|negative regulation of peptidyl-threonine phosphorylation; GO:0010944|negative regulation of transcription by competitive promoter binding; GO:0017015|regulation of transforming growth factor beta receptor signaling pathway; GO:0022409|positive regulation of cell-cell adhesion; GO:0030512|negative regulation of transforming growth factor beta receptor signaling pathway; GO:0030514|negative regulation of BMP signaling pathway; GO:0031397|negative regulation of protein ubiquitination; GO:0031398|positive regulation of protein ubiquitination; GO:0032436|positive regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0032925|regulation of activin receptor signaling pathway; GO:0033137|negative regulation of peptidyl-serine phosphorylation; GO:0034333|adherens junction assembly; GO:0034616|response to laminar fluid shear stress; GO:0034629|cellular protein-containing complex localization; GO:0043433|negative regulation of DNA-binding transcription factor activity; GO:0048844|artery morphogenesis; GO:0050821|protein stabilization; GO:0051444|negative regulation of ubiquitin-protein transferase activity; GO:0055010|ventricular cardiac muscle tissue morphogenesis; GO:0055117|regulation of cardiac muscle contraction; GO:0060373|regulation of ventricular cardiac muscle cell membrane depolarization; GO:0060389|pathway-restricted SMAD protein phosphorylation; GO:0060394|negative regulation of pathway-restricted SMAD protein phosphorylation; GO:0060412|ventricular septum morphogenesis; GO:0071560|cellular response to transforming growth factor beta stimulus; GO:1990830|cellular response to leukemia inhibitory factor; GO:2000317|negative regulation of T-helper 17 type immune response; GO:2000320|negative regulation of T-helper 17 cell differentiation"	GO:0001650|fibrillar center; GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005667|transcription factor complex; GO:0005737|cytoplasm; GO:0005813|centrosome; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0005913|cell-cell adherens junction; GO:0016342|catenin complex; GO:0032991|protein-containing complex	"GO:0003700|DNA-binding transcription factor activity; GO:0005518|collagen binding; GO:0008013|beta-catenin binding; GO:0030617|transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity; GO:0031625|ubiquitin protein ligase binding; GO:0034713|type I transforming growth factor beta receptor binding; GO:0044212|transcription regulatory region DNA binding; GO:0046872|metal ion binding; GO:0048185|activin binding; GO:0070411|I-SMAD binding"	ko:K19631|SMAD7	ko04350|TGF-beta signaling pathway; ko04390|Hippo signaling pathway	1376	XP_427238.2	XP_427238.2 mothers against decapentaplegic homolog 7 isoform X1 [Gallus gallus]	sp|O35253|SMAD7_MOUSE	sp|O35253|SMAD7_MOUSE Mothers against decapentaplegic homolog 7 OS=Mus musculus GN=Smad7 PE=1 SV=1	_	_	_	_	_	PF03166.11|MH2|MH2 domain|ENSGALT00000050099|m.10267:222-386;PF03165.13|MH1|MH1 domain|ENSGALT00000050099|m.10267:66-164
ENSGALG00000037166	0.551829066	0.207527774	1.368931647	0.00645777	0.011826195	up	yes	0.294500731	0.575808511	0.785177955	0.193857854	0.145592453	0.283133015	5	115674	120614	-	ENSGALG00000037166	protein_coding	--	--	--	--	--	2147	NP_001305928.1	NP_001305928.1 uncharacterized protein LOC101752158 [Gallus gallus]	_	_	9031.ENSGALP00000035128	annotation not avaliable	_	_	NOG119851	_
ENSGALG00000037167	74.78233794	24.32648653	1.619769581	6.42E-37	1.41E-35	up	yes	72.51545926	75.18984096	76.6417136	28.98659981	18.39267198	25.60018781	1	48129573	48130279	-	HIST1H103	protein_coding	GO:0006334|nucleosome assembly	GO:0000786|nucleosome; GO:0005634|nucleus	GO:0003677|DNA binding	--	--	707	NP_001292314.1	NP_001292314.1 histone H1.03 [Gallus gallus]	sp|P08285|H103_CHICK	sp|P08285|H103_CHICK Histone H1.03 OS=Gallus gallus PE=3 SV=2	59729.ENSTGUP00000009627	similar to Histone H1.2 (H1d)	_	KOG4012	_	PF00538.16|Linker_histone|linker histone H1 and H5 family|ENSGALT00000079743|m.1194:49-119
ENSGALG00000037214	1.605985045	3.315723012	-1.041254169	7.04E-05	0.000176314	down	yes	2.112614422	1.025054159	1.680286556	3.552580154	3.73531632	2.65927256	4	82748685	82786006	+	ENSGALG00000037214	protein_coding	GO:0007175|negative regulation of epidermal growth factor-activated receptor activity; GO:0042059|negative regulation of epidermal growth factor receptor signaling pathway	GO:0005829|cytosol; GO:0031901|early endosome membrane	GO:0032266|phosphatidylinositol-3-phosphate binding; GO:0046872|metal ion binding	--	--	1696	XP_420832.4	XP_420832.4 lateral signaling target protein 2 homolog isoform X3 [Gallus gallus]	sp|Q0P4S0|LST2_XENTR	sp|Q0P4S0|LST2_XENTR Lateral signaling target protein 2 homolog OS=Xenopus tropicalis GN=zfyve28 PE=2 SV=1	9031.ENSGALP00000025254	"zinc finger, FYVE domain containing 28"	_	KOG1819	_	PF01363.18|FYVE|FYVE zinc finger|ENSGALT00000071151|m.1488:320-380
ENSGALG00000037272	2.183492774	0.973444836	1.157313918	0.000275682	0.000632802	up	yes	1.669913141	2.552966234	2.327598946	1.202811324	1.096056902	0.621466283	7	16290965	16292885	-	HOXD8	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0008595|anterior/posterior axis specification, embryo; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0048705|skeletal system morphogenesis"	GO:0005634|nucleus	"GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific"	ko:K09308|HOX_8	--	1318	XP_015144874.1	XP_015144874.1 homeobox protein Hox-D8 isoform X1 [Gallus gallus]	sp|P13378|HXD8_HUMAN	sp|P13378|HXD8_HUMAN Homeobox protein Hox-D8 OS=Homo sapiens GN=HOXD8 PE=2 SV=2	_	_	_	_	_	PF00046.26|Homeobox|Homeobox domain|ENSGALT00000100823|m.6073:176-232
ENSGALG00000037322	134.6950687	64.55325171	1.061018991	4.30E-21	4.30E-20	up	yes	135.1322166	126.0377792	142.9152102	75.77177289	52.15997742	65.72800482	1	48095104	48095606	+	HIST1H46	protein_coding	"GO:0006334|nucleosome assembly; GO:0006335|DNA replication-dependent nucleosome assembly; GO:0006336|DNA replication-independent nucleosome assembly; GO:0006352|DNA-templated transcription, initiation; GO:0045653|negative regulation of megakaryocyte differentiation; GO:0051290|protein heterotetramerization"	"GO:0000784|nuclear chromosome, telomeric region; GO:0000788|nuclear nucleosome; GO:0005654|nucleoplasm; GO:0016020|membrane; GO:0031012|extracellular matrix; GO:0032991|protein-containing complex; GO:0070062|extracellular exosome"	GO:0003677|DNA binding; GO:0003723|RNA binding; GO:0019904|protein domain specific binding; GO:0042393|histone binding; GO:0046982|protein heterodimerization activity	ko:K11254|H4	ko05034|Alcoholism; ko05203|Viral carcinogenesis; ko05322|Systemic lupus erythematosus	503	XP_008257822.2	XP_008257822.2 PREDICTED: LOW QUALITY PROTEIN: histone H4 [Oryctolagus cuniculus]	sp|P62803|H4_BOVIN	sp|P62803|H4_BOVIN Histone H4 OS=Bos taurus PE=1 SV=2	9031.ENSGALP00000037292	"Histone H4 ; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin,  [...] "	COG2036	KOG3467	_	PF15511.3|CENP-T_C|Centromere kinetochore component CENP-T histone fold|ENSGALT00000070686|m.1176:34-96;PF02969.14|TAF|TATA box binding protein associated factor (TAF)|ENSGALT00000070686|m.1176:59-92
ENSGALG00000037402	0.942466862	2.69435044	-1.505541309	4.38E-10	1.96E-09	down	yes	0.758719737	0.775883695	1.292797153	3.101750145	2.440050074	2.541251102	3	57245588	57248925	+	CTGF	protein_coding	GO:0001558|regulation of cell growth; GO:0007155|cell adhesion; GO:0007165|signal transduction; GO:0007267|cell-cell signaling; GO:0060548|negative regulation of cell death; GO:0071897|DNA biosynthetic process	GO:0031012|extracellular matrix	GO:0005178|integrin binding; GO:0005520|insulin-like growth factor binding; GO:0008201|heparin binding	ko:K06827|CTGF	ko04371|Apelin signaling pathway; ko04390|Hippo signaling pathway	2272	NP_989605.1	NP_989605.1 connective tissue growth factor precursor [Gallus gallus]	sp|O19113|CTGF_PIG	sp|O19113|CTGF_PIG Connective tissue growth factor OS=Sus scrofa GN=CTGF PE=2 SV=1	59729.ENSTGUP00000011980	Connective tissue growth factor Precursor (Hypertrophic chondrocyte-specific protein 24) [Ta [...] 	_	_	NOG72934	PF00007.19|Cys_knot|Cystine-knot domain|ENSGALT00000059653|m.12191:249-339;PF00093.15|VWC|von Willebrand factor type C domain|ENSGALT00000059653|m.12191:98-161;PF00219.15|IGFBP|Insulin-like growth factor binding protein|ENSGALT00000059653|m.12191:24-77;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000059653|m.12191:198-237
ENSGALG00000037407	5.095686466	11.86701128	-1.217994992	5.37E-17	4.14E-16	down	yes	3.957038312	5.8680508	5.461970285	11.95222723	11.03732744	12.61147917	24	437306	446379	-	FAM118B	protein_coding	GO:0030576|Cajal body organization	GO:0015030|Cajal body	--	--	--	1702	XP_021231800.1	XP_021231800.1 protein FAM118B isoform X2 [Numida meleagris]	sp|Q4R836|F118B_MACFA	sp|Q4R836|F118B_MACFA Protein FAM118B OS=Macaca fascicularis GN=FAM118B PE=2 SV=1	9031.ENSGALP00000001598	hypothetical protein LOC419714 	_	_	NOG46711	PF13289.3|SIR2_2|SIR2-like domain|ENSGALT00000061538|m.6054:234-375
ENSGALG00000037467	0.534482205	0.160188522	1.677751157	0.000494439	0.001091795	up	yes	0.652640084	0.365924211	0.584882321	0.093863588	0.258116768	0.128585211	9	1255143	1289866	+	NEU2	protein_coding	GO:0006689|ganglioside catabolic process; GO:0009313|oligosaccharide catabolic process; GO:0051692|cellular oligosaccharide catabolic process	GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0016020|membrane; GO:0043231|intracellular membrane-bounded organelle; GO:1902494|catalytic complex	GO:0004308|exo-alpha-sialidase activity; GO:0052794|exo-alpha-(2->3)-sialidase activity; GO:0052795|exo-alpha-(2->6)-sialidase activity; GO:0052796|exo-alpha-(2->8)-sialidase activity	ko:K12357|NEU2_3_4	ko00511|Other glycan degradation; ko00600|Sphingolipid metabolism	2097	XP_015157234.1	XP_015157234.1 sialidase-2 isoform X1 [Gallus gallus]	sp|Q9JMH3|NEUR2_MOUSE	sp|Q9JMH3|NEUR2_MOUSE Sialidase-2 OS=Mus musculus GN=Neu2 PE=1 SV=1	9031.ENSGALP00000002307	sialidase 2 (cytosolic sialidase)	COG4409	_	_	PF13088.3|BNR_2|BNR repeat-like domain|ENSGALT00000095623|m.8262:36-338
ENSGALG00000037522	19.69089831	39.41801178	-1.000959548	3.44E-50	1.24E-48	down	yes	19.49725499	19.55838896	20.01705099	37.08888449	42.31126649	38.85388435	28	3038438	3080297	-	SBNO2	protein_coding	"GO:0002281|macrophage activation involved in immune response; GO:0006351|transcription, DNA-templated; GO:0030282|bone mineralization; GO:0045892|negative regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0050727|regulation of inflammatory response; GO:0061430|bone trabecula morphogenesis; GO:0071222|cellular response to lipopolysaccharide; GO:0071348|cellular response to interleukin-11; GO:0071354|cellular response to interleukin-6; GO:0072675|osteoclast fusion; GO:1990830|cellular response to leukemia inhibitory factor"	--	--	--	--	5258	XP_015155465.1	XP_015155465.1 protein strawberry notch homolog 2 isoform X1 [Gallus gallus]	sp|A0JND4|SBNO2_BOVIN	sp|A0JND4|SBNO2_BOVIN Protein strawberry notch homolog 2 OS=Bos taurus GN=SBNO2 PE=2 SV=1	_	_	_	_	_	"PF13872.3|AAA_34|P-loop containing NTP hydrolase pore-1|ENSGALT00000058343|m.10097:234-527;PF13871.3|Helicase_C_4|C-terminal domain on Strawberry notch homologue|ENSGALT00000058343|m.10097:759-1037;PF04851.12|ResIII|Type III restriction enzyme, res subunit|ENSGALT00000058343|m.10097:286-444"
ENSGALG00000037525	9.97762207	24.75380921	-1.310020114	9.19E-63	4.91E-61	down	yes	10.06668143	9.905644878	9.960539898	26.18505263	24.2070119	23.86936311	4	85064209	85229240	-	FGFRL1	protein_coding	GO:0008285|negative regulation of cell population proliferation	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0008201|heparin binding	--	--	3397	XP_025005238.1	XP_025005238.1 fibroblast growth factor receptor-like 1 isoform X1 [Gallus gallus]	sp|Q7T2H2|FGRL1_CHICK	sp|Q7T2H2|FGRL1_CHICK Fibroblast growth factor receptor-like 1 OS=Gallus gallus GN=FGFRL1 PE=1 SV=1	9031.ENSGALP00000025315	Fibroblast growth factor receptor-like 1 Precursor ; Has a negative effect on cell proliferation	_	KOG0200	_	PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000047764|m.1535:28-110;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000047764|m.1535:154-232;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000047764|m.1535:246-349;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000047764|m.1535:22-97;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000047764|m.1535:156-219;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000047764|m.1535:239-336;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000047764|m.1535:34-106;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000047764|m.1535:156-227;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000047764|m.1535:247-337;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000047764|m.1535:33-106;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000047764|m.1535:157-227
ENSGALG00000037558	0.524835029	2.507392113	-2.234764088	4.93E-15	3.30E-14	down	yes	0.583687795	0.505771379	0.485045913	2.884129444	2.297970877	2.340076019	28	3688008	3697772	+	ENSGALG00000037558	protein_coding	"GO:0006355|regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II"	GO:0005634|nucleus; GO:0005667|transcription factor complex	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0000980|RNA polymerase II distal enhancer sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003700|DNA-binding transcription factor activity; GO:0042826|histone deacetylase binding; GO:0046983|protein dimerization activity"	ko:K09261|MEF2B	ko04022|cGMP-PKG signaling pathway; ko04371|Apelin signaling pathway	1878	XP_430389.3	XP_430389.3 myocyte-specific enhancer factor 2B isoform X1 [Gallus gallus]	sp|O55087|MEF2B_MOUSE	sp|O55087|MEF2B_MOUSE Myocyte-specific enhancer factor 2B OS=Mus musculus GN=Mef2b PE=1 SV=1	_	_	_	_	_	PF00319.15|SRF-TF|SRF-type transcription factor (DNA-binding and dimerisation domain)|ENSGALT00000100156|m.10294:10-57
ENSGALG00000037597	47.10488962	18.53857814	1.344874464	4.06E-90	4.06E-88	up	yes	45.0692045	49.22283577	47.02262859	18.97404986	17.60547456	19.03621	26	2615310	2619004	-	YOD1	protein_coding	GO:0016236|macroautophagy; GO:0016579|protein deubiquitination; GO:0030433|ubiquitin-dependent ERAD pathway; GO:0030968|endoplasmic reticulum unfolded protein response; GO:0035523|protein K29-linked deubiquitination; GO:0035871|protein K11-linked deubiquitination; GO:0070536|protein K63-linked deubiquitination; GO:0071108|protein K48-linked deubiquitination; GO:1990167|protein K27-linked deubiquitination; GO:1990168|protein K33-linked deubiquitination	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005829|cytosol	GO:0003676|nucleic acid binding; GO:0004843|thiol-dependent ubiquitin-specific protease activity; GO:0031625|ubiquitin protein ligase binding; GO:0046872|metal ion binding; GO:0101005|ubiquitinyl hydrolase activity; GO:1990380|Lys48-specific deubiquitinase activity	"ko:K13719|OTU1,YOD1"	ko04141|Protein processing in endoplasmic reticulum	3422	NP_001026670.1	NP_001026670.1 ubiquitin thioesterase OTU1 [Gallus gallus]	sp|Q5F3A6|OTU1_CHICK	sp|Q5F3A6|OTU1_CHICK Ubiquitin thioesterase OTU1 OS=Gallus gallus GN=YOD1 PE=2 SV=1	9031.ENSGALP00000039556	Ubiquitin thioesterase OTU1 (EC 3.1.2.-); Hydrolase that can remove conjugated ubiquitin fro [...] 	COG5539	KOG3288	_	PF02338.16|OTU|OTU-like cysteine protease|ENSGALT00000064315|m.8030:154-242
ENSGALG00000037619	20.19749373	7.388327987	1.449619235	2.34E-23	2.66E-22	up	yes	17.03466937	20.82932006	22.72849176	7.959701889	7.84605917	6.359222903	27	6221058	6223348	+	HOXB6	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0009952|anterior/posterior pattern specification; GO:0034101|erythrocyte homeostasis; GO:0048704|embryonic skeletal system morphogenesis; GO:0048706|embryonic skeletal system development"	GO:0005634|nucleus	GO:0003700|DNA-binding transcription factor activity; GO:0003723|RNA binding; GO:0043565|sequence-specific DNA binding	ko:K09306|HOX_6	--	996	XP_015154927.1	XP_015154927.1 homeobox protein Hox-B6 isoform X2 [Gallus gallus]	sp|P09023|HXB6_MOUSE	sp|P09023|HXB6_MOUSE Homeobox protein Hox-B6 OS=Mus musculus GN=Hoxb6 PE=1 SV=2	_	_	_	_	_	PF00046.26|Homeobox|Homeobox domain|ENSGALT00000067697|m.9043:145-201
ENSGALG00000037642	0.239380309	0.712085018	-1.533821153	0.005324055	0.009913785	down	yes	0.125904633	0.184626773	0.407609521	0.663023197	0.946101625	0.527130232	13	3188490	3191561	+	SLC23A1	protein_coding	GO:0006814|sodium ion transport; GO:0007420|brain development; GO:0009636|response to toxic substance; GO:0015882|L-ascorbic acid transmembrane transport; GO:0030324|lung development; GO:0070837|dehydroascorbic acid transport; GO:0070904|transepithelial L-ascorbic acid transport	GO:0005737|cytoplasm; GO:0005886|plasma membrane; GO:0009925|basal plasma membrane; GO:0016021|integral component of membrane; GO:0016324|apical plasma membrane; GO:0043229|intracellular organelle; GO:0070062|extracellular exosome	GO:0008520|L-ascorbate:sodium symporter activity; GO:0015081|sodium ion transmembrane transporter activity; GO:0015229|L-ascorbic acid transmembrane transporter activity; GO:0033300|dehydroascorbic acid transmembrane transporter activity; GO:0070890|sodium-dependent L-ascorbate transmembrane transporter activity	"ko:K14611|SLC23A1_2,SVCT1_2"	--	1674	XP_004944825.1	XP_004944825.1 solute carrier family 23 member 1 [Gallus gallus]	sp|Q9Z2J0|S23A1_MOUSE	sp|Q9Z2J0|S23A1_MOUSE Solute carrier family 23 member 1 OS=Mus musculus GN=Slc23a1 PE=1 SV=2	13616.ENSMODP00000014899	"solute carrier family 23 (nucleobase transporters), member 1"	COG2233	KOG1292	_	PF00860.17|Xan_ur_permease|Permease family|ENSGALT00000069134|m.8397:16-433
ENSGALG00000037671	0.115260484	0.664572649	-2.429042469	3.71E-06	1.10E-05	down	yes	0.234942027	0.078299863	0.032539562	0.698950231	0.658878146	0.63588957	1	56805534	56829441	+	ENSGALG00000037671	protein_coding	--	--	"GO:0004730|pseudouridylate synthase activity; GO:0016798|hydrolase activity, acting on glycosyl bonds; GO:0046872|metal ion binding"	ko:K16330|K16330	ko00240|Pyrimidine metabolism	2467	XP_015142900.1	XP_015142900.1 pseudouridine-metabolizing bifunctional protein C1861.05 isoform X1 [Gallus gallus]	sp|Q8RCT3|PSUG_CALS4	sp|Q8RCT3|PSUG_CALS4 Pseudouridine-5'-phosphate glycosidase OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) GN=psuG PE=3 SV=1	9031.ENSGALP00000020933	annotation not avaliable	COG0524;COG2313	KOG3009	_	PF04227.9|Indigoidine_A|Indigoidine synthase A like protein|ENSGALT00000067177|m.1658:1-268;PF00294.21|PfkB|pfkB family carbohydrate kinase|ENSGALT00000067177|m.1658:293-617
ENSGALG00000037726	26.17894028	10.78250224	1.278928291	5.02E-35	1.00E-33	up	yes	26.13918258	25.15021577	27.24742248	10.4704371	10.95460089	10.92246872	3	64899435	64901566	-	MARCKS	protein_coding	--	GO:0005737|cytoplasm; GO:0005856|cytoskeleton; GO:0016020|membrane	GO:0003779|actin binding; GO:0005516|calmodulin binding	ko:K12561|MARCKS	ko04666|Fc gamma R-mediated phagocytosis; ko05206|MicroRNAs in cancer	1149	XP_017496873.1	XP_017496873.1 PREDICTED: fibrous sheath CABYR-binding protein-like [Manis javanica]	sp|P16527|MARCS_CHICK	sp|P16527|MARCS_CHICK Myristoylated alanine-rich C-kinase substrate OS=Gallus gallus GN=MARCKS PE=1 SV=2	_	_	_	_	_	PF02063.14|MARCKS|MARCKS family|ENSGALT00000047609|m.12347:2-277
ENSGALG00000037780	16.47149029	40.11263044	-1.283569492	2.61E-42	7.30E-41	down	yes	17.35208557	15.2981077	16.76427761	41.62924088	37.96237269	40.74627777	20	11499475	11529472	+	PMEPA1	protein_coding	GO:0010991|negative regulation of SMAD protein complex assembly; GO:0030512|negative regulation of transforming growth factor beta receptor signaling pathway; GO:0060394|negative regulation of pathway-restricted SMAD protein phosphorylation	GO:0000139|Golgi membrane; GO:0010008|endosome membrane; GO:0016021|integral component of membrane; GO:0031901|early endosome membrane	--	--	--	1245	NP_001026663.1	NP_001026663.1 protein TMEPAI [Gallus gallus]	sp|D2KUZ7|PMEPA_XENLA	sp|D2KUZ7|PMEPA_XENLA Protein TMEPAI OS=Xenopus laevis GN=pmepa1 PE=2 SV=1	13616.ENSMODP00000020623	"prostate transmembrane protein, androgen induced 1"	_	_	NOG27420	_
ENSGALG00000037791	2.719200772	16.28200678	-2.577613885	1.22E-121	2.94E-119	down	yes	2.584396755	2.892188233	2.681017328	15.24047896	17.36258206	16.24295932	12	15745789	15810437	-	FRMD4B	protein_coding	GO:0090162|establishment of epithelial cell polarity	GO:0001726|ruffle; GO:0005615|extracellular space; GO:0005737|cytoplasm; GO:0005856|cytoskeleton; GO:0005912|adherens junction; GO:0005923|bicellular tight junction	--	--	--	3099	XP_423748.2	XP_423748.2 FERM domain-containing protein 4B isoform X4 [Gallus gallus]	sp|Q9Y2L6|FRM4B_HUMAN	sp|Q9Y2L6|FRM4B_HUMAN FERM domain-containing protein 4B OS=Homo sapiens GN=FRMD4B PE=1 SV=4	_	_	_	_	_	PF11819.5|DUF3338|Domain of unknown function (DUF3338)|ENSGALT00000069260|m.8022:392-525;PF09380.7|FERM_C|FERM C-terminal PH-like domain|ENSGALT00000069260|m.8022:261-361;PF00373.15|FERM_M|FERM central domain|ENSGALT00000069260|m.8022:148-257;PF09379.7|FERM_N|FERM N-terminal domain|ENSGALT00000069260|m.8022:63-122
ENSGALG00000037838	1544.782421	297.9839941	2.374057832	6.43E-148	2.43E-145	up	yes	1542.778938	1635.544124	1456.024201	244.6702572	307.3971749	341.8845503	MT	16184	16705	-	ND6	protein_coding	--	GO:0005739|mitochondrion; GO:0016021|integral component of membrane; GO:0031966|mitochondrial membrane; GO:0070469|respirasome	GO:0008137|NADH dehydrogenase (ubiquinone) activity	ko:K03884|ND6	ko00190|Oxidative phosphorylation; ko01100|Metabolic pathways; ko04723|Retrograde endocannabinoid signaling; ko05012|Parkinson's disease	522	NP_006927.1	NP_006927.1 NADH dehydrogenase subunit 6 (mitochondrion) [Gallus gallus]	sp|P18941|NU6M_CHICK	sp|P18941|NU6M_CHICK NADH-ubiquinone oxidoreductase chain 6 OS=Gallus gallus GN=MT-ND6 PE=3 SV=1	9031.ENSGALP00000034624	NADH-ubiquinone oxidoreductase chain 6 (EC 1.6.5.3)(NADH dehydrogenase subunit 6); Core subu [...] 	_	_	NOG70008	_
ENSGALG00000037860	15.92703084	7.86504637	1.017022548	5.00E-11	2.43E-10	up	yes	17.02534552	14.50593458	16.24981241	6.986239497	8.569860633	8.039038981	22	3850881	3853124	+	ENSGALG00000037860	protein_coding	GO:0006493|protein O-linked glycosylation; GO:0035511|oxidative DNA demethylation; GO:0044727|DNA demethylation of male pronucleus; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0080111|DNA demethylation; GO:0080182|histone H3-K4 trimethylation	GO:0001939|female pronucleus; GO:0001940|male pronucleus; GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm	GO:0003677|DNA binding; GO:0046872|metal ion binding; GO:0070579|methylcytosine dioxygenase activity	--	--	783	XP_021230778.1	XP_021230778.1 methylcytosine dioxygenase TET3 isoform X1 [Numida meleagris]	sp|Q8BG87|TET3_MOUSE	sp|Q8BG87|TET3_MOUSE Methylcytosine dioxygenase TET3 OS=Mus musculus GN=Tet3 PE=1 SV=3	_	_	_	_	_	PF12851.4|Tet_JBP|Oxygenase domain of the 2OGFeDO superfamily|ENSGALT00000084862|m.4930:1-188
ENSGALG00000037863	105.5138035	41.14821672	1.35831609	6.42E-36	1.33E-34	up	yes	106.2777775	101.562508	108.7011249	46.82604681	37.90006653	38.71853682	2	52114901	52118653	+	SEC61G	protein_coding	GO:0045047|protein targeting to ER	GO:0005789|endoplasmic reticulum membrane; GO:0016021|integral component of membrane	GO:0015450|P-P-bond-hydrolysis-driven protein transmembrane transporter activity	"ko:K07342|SEC61G,SSS1,secE"	ko03060|Protein export; ko04141|Protein processing in endoplasmic reticulum; ko04145|Phagosome; ko05110|Vibrio cholerae infection	353	XP_001236152.2	XP_001236152.2 protein transport protein Sec61 subunit gamma isoform X1 [Gallus gallus]	sp|Q3T104|SC61G_BOVIN	sp|Q3T104|SC61G_BOVIN Protein transport protein Sec61 subunit gamma OS=Bos taurus GN=SEC61G PE=3 SV=1	_	_	_	_	_	_
ENSGALG00000037869	0.755498265	0.308633094	1.264502989	0.00082289	0.001755485	up	yes	0.636400747	1.145314424	0.484779623	0.190416695	0.331778678	0.403703911	25	3351408	3362735	+	ENSGALG00000037869	protein_coding	GO:0006182|cGMP biosynthetic process; GO:0007166|cell surface receptor signaling pathway; GO:0007168|receptor guanylyl cyclase signaling pathway; GO:0035556|intracellular signal transduction; GO:0042417|dopamine metabolic process; GO:0048662|negative regulation of smooth muscle cell proliferation; GO:0097746|regulation of blood vessel diameter	"GO:0005886|plasma membrane; GO:0008074|guanylate cyclase complex, soluble; GO:0016021|integral component of membrane; GO:0043235|receptor complex"	GO:0004383|guanylate cyclase activity; GO:0004672|protein kinase activity; GO:0005524|ATP binding; GO:0005525|GTP binding; GO:0016941|natriuretic peptide receptor activity; GO:0017046|peptide hormone binding; GO:0019901|protein kinase binding; GO:0042562|hormone binding	ko:K13140|INTS3	--	3580	XP_015153964.2	XP_015153964.2 atrial natriuretic peptide receptor 1 [Gallus gallus]	sp|P18910|ANPRA_RAT	sp|P18910|ANPRA_RAT Atrial natriuretic peptide receptor 1 OS=Rattus norvegicus GN=Npr1 PE=1 SV=1	_	_	_	_	_	PF00211.17|Guanylate_cyc|Adenylate and Guanylate cyclase catalytic domain|ENSGALT00000107299|m.7200:897-1071;PF01094.25|ANF_receptor|Receptor family ligand binding region|ENSGALT00000107299|m.7200:58-419;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000107299|m.7200:587-831;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000107299|m.7200:580-828
ENSGALG00000037946	28.0326011	8.8854927	1.656473753	3.60E-79	2.90E-77	up	yes	29.89868746	26.6441542	27.55496165	9.261689391	8.487928389	8.90686032	33	6353086	6357287	-	RBM4	protein_coding	GO:0006397|mRNA processing; GO:0006417|regulation of translation; GO:0007623|circadian rhythm; GO:0008380|RNA splicing; GO:0010628|positive regulation of gene expression; GO:0032922|circadian regulation of gene expression; GO:0043153|entrainment of circadian clock by photoperiod	GO:0005654|nucleoplasm; GO:0005730|nucleolus; GO:0005829|cytosol; GO:0032991|protein-containing complex	GO:0003723|RNA binding; GO:0008270|zinc ion binding	ko:K13187|RBM4	--	2217	XP_015128487.1	XP_015128487.1 RNA-binding protein 4B isoform X1 [Gallus gallus]	sp|Q06AT9|RBM4B_PIG	sp|Q06AT9|RBM4B_PIG RNA-binding protein 4B OS=Sus scrofa GN=RBM4B PE=2 SV=1	_	_	_	_	_	"PF00076.19|RRM_1|RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)|ENSGALT00000095444|m.15355:6-64;PF00076.19|RRM_1|RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)|ENSGALT00000095444|m.15355:83-143;PF13893.3|RRM_5|RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)|ENSGALT00000095444|m.15355:14-75;PF13893.3|RRM_5|RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)|ENSGALT00000095444|m.15355:113-149;PF00098.20|zf-CCHC|Zinc knuckle|ENSGALT00000095444|m.15355:163-178"
ENSGALG00000037953	198.2307858	40.36900603	2.295576509	6.95E-256	8.40E-253	up	yes	208.0135475	192.277367	194.4014428	37.53293786	41.40628259	42.16779762	33	7117397	7121192	+	TUBA1A	protein_coding	GO:0007017|microtubule-based process	GO:0005737|cytoplasm; GO:0005874|microtubule	GO:0003924|GTPase activity; GO:0005200|structural constituent of cytoskeleton; GO:0005525|GTP binding	ko:K07374|TUBA	ko04145|Phagosome; ko04210|Apoptosis; ko04530|Tight junction; ko04540|Gap junction; ko05130|Pathogenic Escherichia coli infection	1609	NP_035783.1	NP_035783.1 tubulin alpha-1A chain [Mus musculus]	sp|P68362|TBA1A_CRIGR	sp|P68362|TBA1A_CRIGR Tubulin alpha-1A chain OS=Cricetulus griseus GN=TUBA1A PE=2 SV=1	8364.ENSXETP00000024445	annotation not avaliable	COG5023	KOG1376	_	"PF00091.22|Tubulin|Tubulin/FtsZ family, GTPase domain|ENSGALT00000056511|m.15637:21-231;PF03953.14|Tubulin_C|Tubulin C-terminal domain|ENSGALT00000056511|m.15637:281-409"
ENSGALG00000037989	14.80822998	33.53010656	-1.178514143	1.17E-45	3.67E-44	down	yes	15.12990753	14.95850919	14.33627323	32.55024324	35.42339893	32.61667751	1	106593970	106604799	+	IL10R2	protein_coding	GO:0051607|defense response to virus	GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0070062|extracellular exosome	GO:0004920|interleukin-10 receptor activity	"ko:K05135|IL10RB,CD210B"	ko04060|Cytokine-cytokine receptor interaction; ko04630|Jak-STAT signaling pathway; ko05145|Toxoplasmosis; ko05152|Tuberculosis; ko05169|Epstein-Barr virus infection	1926	XP_015154738.1	XP_015154738.1 interleukin-10 receptor subunit beta isoform X1 [Gallus gallus]	sp|Q61190|I10R2_MOUSE	sp|Q61190|I10R2_MOUSE Interleukin-10 receptor subunit beta OS=Mus musculus GN=Il10rb PE=1 SV=1	9031.ENSGALP00000029730	"interleukin 10 receptor, beta "	_	_	NOG47180	"PF09294.7|Interfer-bind|Interferon-alpha/beta receptor, fibronectin type III|ENSGALT00000073701|m.3050:114-217;PF01108.14|Tissue_fac|Tissue factor|ENSGALT00000073701|m.3050:9-103"
ENSGALG00000038043	1.590114486	3.370858068	-1.07921432	8.47E-08	3.04E-07	down	yes	1.911997326	1.4018781	1.456468033	3.018943642	3.83369707	3.259933493	6	20620876	20653897	+	HECTD2	protein_coding	--	GO:0005737|cytoplasm	GO:0004842|ubiquitin-protein transferase activity; GO:0061630|ubiquitin protein ligase activity	ko:K12232|HECTD2	--	2370	XP_004942207.2	XP_004942207.2 LOW QUALITY PROTEIN: probable E3 ubiquitin-protein ligase HECTD2 [Gallus gallus]	sp|Q8CDU6|HECD2_MOUSE	sp|Q8CDU6|HECD2_MOUSE Probable E3 ubiquitin-protein ligase HECTD2 OS=Mus musculus GN=Hectd2 PE=1 SV=2	9031.ENSGALP00000002755	hypothetical LOC425640	COG5021	KOG0941	_	PF00632.22|HECT|HECT-domain (ubiquitin-transferase)|ENSGALT00000079673|m.4892:480-789
ENSGALG00000038096	3.624827192	8.679141005	-1.257326785	4.61E-37	1.02E-35	down	yes	3.649856578	3.547764663	3.676860335	8.237321636	8.929041936	8.871059444	19	9342031	9361245	-	NOS2	protein_coding	GO:0006809|nitric oxide biosynthetic process; GO:0006954|inflammatory response; GO:0007263|nitric oxide mediated signal transduction; GO:0018119|peptidyl-cysteine S-nitrosylation; GO:0031284|positive regulation of guanylate cyclase activity; GO:0032310|prostaglandin secretion; GO:0042742|defense response to bacterium; GO:0045776|negative regulation of blood pressure; GO:0072604|interleukin-6 secretion; GO:0072606|interleukin-8 secretion; GO:0097755|positive regulation of blood vessel diameter; GO:1900015|regulation of cytokine production involved in inflammatory response	GO:0005622|intracellular	GO:0003958|NADPH-hemoprotein reductase activity; GO:0004517|nitric-oxide synthase activity; GO:0005506|iron ion binding; GO:0005516|calmodulin binding; GO:0010181|FMN binding; GO:0020037|heme binding; GO:0050660|flavin adenine dinucleotide binding; GO:0050661|NADP binding	ko:K13241|NOS2	ko00220|Arginine biosynthesis; ko00330|Arginine and proline metabolism; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko04020|Calcium signaling pathway; ko04066|HIF-1 signaling pathway; ko04146|Peroxisome; ko04371|Apelin signaling pathway; ko05132|Salmonella infection; ko05133|Pertussis; ko05140|Leishmaniasis; ko05142|Chagas disease (American trypanosomiasis); ko05145|Toxoplasmosis; ko05146|Amoebiasis; ko05152|Tuberculosis; ko05200|Pathways in cancer; ko05222|Small cell lung cancer	4432	NP_990292.1	"NP_990292.1 nitric oxide synthase, inducible [Gallus gallus]"	sp|Q90703|NOS2_CHICK	"sp|Q90703|NOS2_CHICK Nitric oxide synthase, inducible OS=Gallus gallus GN=NOS2 PE=2 SV=1"	9031.ENSGALP00000034026	"Nitric oxide synthase, inducible (EC 1.14.13.39)(Inducible NO synthase)(Inducible NOS)(iNOS) [...] "	COG0369;COG4362	KOG1158	_	"PF02898.12|NO_synthase|Nitric oxide synthase, oxygenase domain|ENSGALT00000072375|m.14209:134-494;PF00667.17|FAD_binding_1|FAD binding domain|ENSGALT00000072375|m.14209:725-944;PF00258.22|Flavodoxin_1|Flavodoxin|ENSGALT00000072375|m.14209:538-669;PF00175.18|NAD_binding_1|Oxidoreductase NAD-binding domain|ENSGALT00000072375|m.14209:976-1089"
ENSGALG00000038162	0.357447138	0.0880632	1.905752962	3.27E-06	9.79E-06	up	yes	0.420871742	0.338689237	0.312780435	0.07722446	0.060897525	0.126067616	3	63853190	63861087	-	CALHM5	protein_coding	GO:0034220|ion transmembrane transport	GO:0005887|integral component of plasma membrane; GO:0070062|extracellular exosome	GO:0005261|cation channel activity	--	--	5133	NP_001072960.1	NP_001072960.1 calcium homeostasis modulator protein 5 [Gallus gallus]	sp|Q8N5C1|CAHM5_HUMAN	sp|Q8N5C1|CAHM5_HUMAN Calcium homeostasis modulator protein 5 OS=Homo sapiens GN=CALHM5 PE=2 SV=1	9031.ENSGALP00000024082	Putative uncharacterized protein 	_	_	NOG72034	PF14798.3|Ca_hom_mod|Calcium homeostasis modulator|ENSGALT00000067847|m.12327:1-250
ENSGALG00000038223	0.10032801	1.934267163	-4.139355467	2.36E-27	3.31E-26	down	yes	0.088885103	0.117307143	0.094791783	2.099653346	1.764717416	1.938430726	17	2832458	2858968	-	WHRN	protein_coding	GO:0001895|retina homeostasis; GO:0007605|sensory perception of sound; GO:0010628|positive regulation of gene expression; GO:0021694|cerebellar Purkinje cell layer formation; GO:0045184|establishment of protein localization; GO:0050953|sensory perception of light stimulus; GO:0060088|auditory receptor cell stereocilium organization; GO:0060122|inner ear receptor cell stereocilium organization; GO:1990227|paranodal junction maintenance	GO:0001917|photoreceptor inner segment; GO:0002141|stereocilia ankle link; GO:0002142|stereocilia ankle link complex; GO:0005737|cytoplasm; GO:0005884|actin filament; GO:0005929|cilium; GO:0030426|growth cone; GO:0032391|photoreceptor connecting cilium; GO:0032420|stereocilium; GO:0032421|stereocilium bundle; GO:0032426|stereocilium tip; GO:0036064|ciliary basal body; GO:1990075|periciliary membrane compartment; GO:1990696|USH2 complex	GO:0042803|protein homodimerization activity; GO:0046982|protein heterodimerization activity	--	--	2781	XP_427028.5	XP_427028.5 whirlin isoform X1 [Gallus gallus]	sp|Q80VW5|WHRN_MOUSE	sp|Q80VW5|WHRN_MOUSE Whirlin OS=Mus musculus GN=Whrn PE=1 SV=3	59729.ENSTGUP00000003274	Whirlin (Autosomal recessive deafness type 31 protein) [Taeniopygia guttata]	_	KOG3528	_	PF00595.21|PDZ|PDZ domain (Also known as DHR or GLGF)|ENSGALT00000094849|m.11862:127-205;PF00595.21|PDZ|PDZ domain (Also known as DHR or GLGF)|ENSGALT00000094849|m.11862:267-341
ENSGALG00000038254	0.030673404	1.003921179	-4.639715958	4.44E-12	2.34E-11	down	yes	0	0.092020212	0	1.140869538	0.835550793	1.035343205	6	32353434	32362063	+	ENSGALG00000038254	protein_coding	"GO:0006931|substrate-dependent cell migration, cell attachment to substrate; GO:0007049|cell cycle; GO:0008283|cell population proliferation; GO:0032023|trypsinogen activation; GO:0051301|cell division"	GO:0016021|integral component of membrane; GO:0030658|transport vesicle membrane; GO:0042589|zymogen granule membrane	--	ko:K13912|DMBT1	ko04970|Salivary secretion	2435	XP_015144377.2	XP_015144377.2 LOW QUALITY PROTEIN: CUB and zona pellucida-like domain-containing protein 1 [Gallus gallus]	sp|Q86UP6|CUZD1_HUMAN	sp|Q86UP6|CUZD1_HUMAN CUB and zona pellucida-like domain-containing protein 1 OS=Homo sapiens GN=CUZD1 PE=2 SV=1	9031.ENSGALP00000037902	CUB and zona pellucida-like domains 1	_	KOG4292	NOG27919	PF00100.20|Zona_pellucida|Zona pellucida-like domain|ENSGALT00000100675|m.5440:50-287;PF00431.17|CUB|CUB domain|ENSGALT00000100675|m.5441:39-128;PF00431.17|CUB|CUB domain|ENSGALT00000100675|m.5441:140-220
ENSGALG00000038265	4.977928601	11.44716887	-1.19973787	9.71E-17	7.33E-16	down	yes	6.151867608	4.426715367	4.355202829	11.81093317	12.58126485	9.949308575	2	33231086	33475464	+	CREB5	protein_coding	"GO:0006366|transcription by RNA polymerase II; GO:0045893|positive regulation of transcription, DNA-templated"	GO:0005634|nucleus; GO:0070062|extracellular exosome	GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity; GO:0046872|metal ion binding	"ko:K09047|CREB5,CREBPA"	ko04022|cGMP-PKG signaling pathway; ko04024|cAMP signaling pathway; ko04151|PI3K-Akt signaling pathway; ko04152|AMPK signaling pathway; ko04211|Longevity regulating pathway; ko04261|Adrenergic signaling in cardiomyocytes; ko04668|TNF signaling pathway; ko04725|Cholinergic synapse; ko04728|Dopaminergic synapse; ko04911|Insulin secretion; ko04915|Estrogen signaling pathway; ko04918|Thyroid hormone synthesis; ko04922|Glucagon signaling pathway; ko04925|Aldosterone synthesis and secretion; ko04931|Insulin resistance; ko04962|Vasopressin-regulated water reabsorption; ko05016|Huntington's disease; ko05030|Cocaine addiction; ko05031|Amphetamine addiction; ko05034|Alcoholism; ko05161|Hepatitis B; ko05203|Viral carcinogenesis; ko05215|Prostate cancer	2015	XP_013027367.1	XP_013027367.1 PREDICTED: cyclic AMP-responsive element-binding protein 5 isoform X1 [Anser cygnoides domesticus]	sp|Q02930|CREB5_HUMAN	sp|Q02930|CREB5_HUMAN Cyclic AMP-responsive element-binding protein 5 OS=Homo sapiens GN=CREB5 PE=1 SV=3	9031.ENSGALP00000018139	cAMP responsive element binding protein 5	_	KOG1414	_	PF00170.18|bZIP_1|bZIP transcription factor|ENSGALT00000054279|m.301:539-596;PF07716.12|bZIP_2|Basic region leucine zipper|ENSGALT00000054279|m.301:537-589;PF03131.14|bZIP_Maf|bZIP Maf transcription factor|ENSGALT00000054279|m.301:539-595
ENSGALG00000038399	5.217715956	15.05318739	-1.526774418	9.12E-79	7.25E-77	down	yes	5.550664348	4.764427772	5.338055747	15.16313083	15.19718973	14.79924161	26	1736524	1776457	-	PLEKHA6	protein_coding	--	--	--	--	--	5063	XP_015154585.1	XP_015154585.1 pleckstrin homology domain-containing family A member 6 isoform X13 [Gallus gallus]	sp|Q7TQG1|PKHA6_MOUSE	sp|Q7TQG1|PKHA6_MOUSE Pleckstrin homology domain-containing family A member 6 OS=Mus musculus GN=Plekha6 PE=1 SV=1	9031.ENSGALP00000000818	"pleckstrin homology domain containing, family A member 6"	_	KOG1738	_	PF00169.26|PH|PH domain|ENSGALT00000099172|m.7887:126-222;PF15413.3|PH_11|Pleckstrin homology domain|ENSGALT00000099172|m.7887:130-221
ENSGALG00000038432	0.156317145	0.375266815	-1.211921029	0.016172599	0.02736884	down	yes	0.110502109	0.162040485	0.196408839	0.360231458	0.313206126	0.452362861	3	9011945	9069715	+	ENSGALG00000038432	protein_coding	GO:0000187|activation of MAPK activity; GO:0007165|signal transduction; GO:0007169|transmembrane receptor protein tyrosine kinase signaling pathway; GO:0008283|cell population proliferation; GO:0016310|phosphorylation; GO:0021766|hippocampus development; GO:0030534|adult behavior; GO:0036269|swimming behavior; GO:0042127|regulation of cell population proliferation; GO:0042981|regulation of apoptotic process; GO:0046777|protein autophosphorylation; GO:0048666|neuron development; GO:0051092|positive regulation of NF-kappaB transcription factor activity; GO:0060159|regulation of dopamine receptor signaling pathway; GO:0090648|response to environmental enrichment	GO:0005622|intracellular; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0032991|protein-containing complex; GO:0070062|extracellular exosome	GO:0004704|NF-kappaB-inducing kinase activity; GO:0004713|protein tyrosine kinase activity; GO:0004714|transmembrane receptor protein tyrosine kinase activity; GO:0005524|ATP binding; GO:0042802|identical protein binding	"ko:K05119|ALK,CD246"	ko05223|Non-small cell lung cancer	2861	XP_025004685.1	XP_025004685.1 ALK tyrosine kinase receptor isoform X2 [Gallus gallus]	sp|Q9UM73|ALK_HUMAN	sp|Q9UM73|ALK_HUMAN ALK tyrosine kinase receptor OS=Homo sapiens GN=ALK PE=1 SV=3	9031.ENSGALP00000014686	anaplastic lymphoma kinase (Ki-1)	COG0515	KOG1095	_	"PF00629.20|MAM|MAM domain, meprin/A5/mu|ENSGALT00000078898|m.10765:95-216"
ENSGALG00000038440	1.935478089	4.405284336	-1.182381616	0.000421226	0.000939922	down	yes	1.627854785	1.633271479	2.545308002	4.576246169	3.761209399	4.878397441	7	10211054	10219664	+	COQ10B	protein_coding	GO:0006744|ubiquinone biosynthetic process; GO:0045333|cellular respiration	GO:0005739|mitochondrion; GO:0005743|mitochondrial inner membrane	GO:0048039|ubiquinone binding	ko:K18588|COQ10	--	615	OXB57079.1	OXB57079.1 hypothetical protein ASZ78_002367 [Callipepla squamata]	sp|Q9H8M1|CQ10B_HUMAN	"sp|Q9H8M1|CQ10B_HUMAN Coenzyme Q-binding protein COQ10 homolog B, mitochondrial OS=Homo sapiens GN=COQ10B PE=2 SV=1"	9031.ENSGALP00000013042	coenzyme Q10 homolog B (S. cerevisiae)	COG2867	KOG3177	_	PF03364.17|Polyketide_cyc|Polyketide cyclase / dehydrase and lipid transport|ENSGALT00000063468|m.5830:50-179
ENSGALG00000038494	25.14465208	53.41806767	-1.086772605	1.24E-47	4.16E-46	down	yes	26.94984879	22.91560019	25.56850724	53.79621377	54.41655334	52.04143592	11	15556046	15651941	+	CMIP	protein_coding	--	GO:0005654|nucleoplasm; GO:0005829|cytosol	--	--	--	2389	XP_005018326.2	XP_005018326.2 C-Maf-inducing protein isoform X1 [Anas platyrhynchos]	sp|Q8IY22|CMIP_HUMAN	sp|Q8IY22|CMIP_HUMAN C-Maf-inducing protein OS=Homo sapiens GN=CMIP PE=1 SV=3	9031.ENSGALP00000019575	c-Maf-inducing protein	_	_	NOG43637	_
ENSGALG00000038515	6.658373951	18.02210642	-1.43516102	1.47E-49	5.23E-48	down	yes	6.971554918	6.255294761	6.748272173	18.72580964	16.74899627	18.59151335	14	3626463	3636842	+	LFNG	protein_coding	GO:0007389|pattern specification process; GO:0008593|regulation of Notch signaling pathway; GO:0036066|protein O-linked fucosylation	GO:0030173|integral component of Golgi membrane	GO:0033829|O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity; GO:0046872|metal ion binding	ko:K05948|FNG	ko00514|Other types of O-glycan biosynthesis; ko04330|Notch signaling pathway	2736	NP_990279.1	"NP_990279.1 beta-1,3-N-acetylglucosaminyltransferase lunatic fringe precursor [Gallus gallus]"	sp|O12971|LFNG_CHICK	"sp|O12971|LFNG_CHICK Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe OS=Gallus gallus GN=LFNG PE=2 SV=1"	9258.ENSOANP00000006848	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	_	_	NOG70217	PF02434.13|Fringe|Fringe-like|ENSGALT00000073543|m.9309:113-362
ENSGALG00000038574	0.736188889	0.268325681	1.422766848	0.002935532	0.005714521	up	yes	1.105249729	0.347301455	0.756015483	0.40725324	0.19625896	0.201464842	18	4814672	4820273	-	ENSGALG00000038574	protein_coding	GO:0007605|sensory perception of sound; GO:0007626|locomotory behavior; GO:0042472|inner ear morphogenesis	GO:0005737|cytoplasm; GO:0016459|myosin complex; GO:0032420|stereocilium; GO:0070062|extracellular exosome	GO:0003774|motor activity; GO:0003779|actin binding; GO:0005516|calmodulin binding; GO:0005524|ATP binding	ko:K10361|MYO15	--	2336	XP_015150815.1	XP_015150815.1 myosin XVB isoform X3 [Gallus gallus]	sp|Q9UKN7|MYO15_HUMAN	sp|Q9UKN7|MYO15_HUMAN Unconventional myosin-XV OS=Homo sapiens GN=MYO15A PE=1 SV=2	9031.ENSGALP00000003843	similar to Myo15b protein	_	KOG4229	_	PF00784.14|MyTH4|MyTH4 domain|ENSGALT00000068836|m.12719:33-107;PF00373.15|FERM_M|FERM central domain|ENSGALT00000068836|m.12719:208-322
ENSGALG00000038671	7.022981927	2.171942311	1.688523552	2.58E-08	9.79E-08	up	yes	8.911432777	3.683524169	8.473988836	1.642264486	2.247125596	2.62643685	18	9873216	9874223	+	ENSGALG00000038671	protein_coding	--	--	--	--	--	881	NP_001006423.1	NP_001006423.1 uncharacterized protein LOC422090 [Gallus gallus]	sp|Q77MQ0|VG87_GAHVM	sp|Q77MQ0|VG87_GAHVM Uncharacterized gene 87 protein OS=Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987) GN=MDV087 PE=4 SV=1	9031.ENSGALP00000037574	hypothetical protein LOC422090 	_	_	NOG113035	PF02393.13|US22|US22 like|ENSGALT00000047977|m.13136:7-100
ENSGALG00000038678	14.66219992	40.00647628	-1.447508932	2.44E-86	2.24E-84	down	yes	13.63395674	15.63957429	14.71306872	37.96202001	42.39335829	39.66405055	2	100148458	100212328	+	EPB41L3	protein_coding	GO:0001558|regulation of cell growth; GO:0002175|protein localization to paranode region of axon; GO:0006915|apoptotic process; GO:0007016|cytoskeletal anchoring at plasma membrane; GO:0008360|regulation of cell shape; GO:0030865|cortical cytoskeleton organization; GO:0030866|cortical actin cytoskeleton organization; GO:0030913|paranodal junction assembly; GO:0031032|actomyosin structure organization; GO:0043217|myelin maintenance; GO:0048812|neuron projection morphogenesis; GO:0071205|protein localization to juxtaparanode region of axon; GO:0072659|protein localization to plasma membrane	GO:0005829|cytosol; GO:0005856|cytoskeleton; GO:0005886|plasma membrane; GO:0005911|cell-cell junction; GO:0014069|postsynaptic density; GO:0030673|axolemma; GO:0033270|paranode region of axon; GO:0044224|juxtaparanode region of axon	GO:0003779|actin binding; GO:0005200|structural constituent of cytoskeleton	"ko:K06107|EPB41,4.1R"	--	4121	XP_015138050.1	XP_015138050.1 band 4.1-like protein 3 isoform X2 [Gallus gallus]	sp|Q9Y2J2|E41L3_HUMAN	sp|Q9Y2J2|E41L3_HUMAN Band 4.1-like protein 3 OS=Homo sapiens GN=EPB41L3 PE=1 SV=2	9031.ENSGALP00000023785	erythrocyte membrane protein band 4.1-like 3	_	KOG3527	_	PF05902.10|4_1_CTD|4.1 protein C-terminal domain (CTD)|ENSGALT00000094561|m.1551:1253-1359;PF04382.10|SAB|SAB domain|ENSGALT00000094561|m.1551:735-783;PF09380.7|FERM_C|FERM C-terminal PH-like domain|ENSGALT00000094561|m.1551:311-395;PF09379.7|FERM_N|FERM N-terminal domain|ENSGALT00000094561|m.1551:120-181;PF08736.8|FA|FERM adjacent (FA)|ENSGALT00000094561|m.1551:404-445;PF00373.15|FERM_M|FERM central domain|ENSGALT00000094561|m.1551:199-307
ENSGALG00000038708	1.423901885	0.677379495	1.06076759	0.001385161	0.002858565	up	yes	1.403224743	0.908813614	1.959667297	0.589399497	0.554970257	0.887768731	23	5088088	5103045	+	KCNQ4	protein_coding	GO:0006813|potassium ion transport; GO:0007605|sensory perception of sound; GO:0042472|inner ear morphogenesis	GO:0005886|plasma membrane; GO:0008076|voltage-gated potassium channel complex; GO:0009925|basal plasma membrane; GO:0016021|integral component of membrane	GO:0005249|voltage-gated potassium channel activity; GO:0005267|potassium channel activity	ko:K04929|KCNQ4	ko04725|Cholinergic synapse	2004	XP_024998830.1	XP_024998830.1 potassium voltage-gated channel subfamily KQT member 4 isoform X3 [Gallus gallus]	sp|P56696|KCNQ4_HUMAN	sp|P56696|KCNQ4_HUMAN Potassium voltage-gated channel subfamily KQT member 4 OS=Homo sapiens GN=KCNQ4 PE=1 SV=2	9598.ENSPTRP00000001033	"potassium voltage-gated channel, KQT-like subfamily, member 4"	COG1226	KOG1419	_	PF03520.11|KCNQ_channel|KCNQ voltage-gated potassium channel|ENSGALT00000055144|m.5674:433-618;PF00520.28|Ion_trans|Ion transport protein|ENSGALT00000055144|m.5674:79-301;PF07885.13|Ion_trans_2|Ion channel|ENSGALT00000055144|m.5674:223-297
ENSGALG00000038710	15.37392574	6.812535415	1.173043821	9.00E-25	1.11E-23	up	yes	14.51626398	15.90494205	15.7005712	7.25981243	6.324314042	6.853479773	1	71797826	71804003	-	MANSC1	protein_coding	--	--	--	--	--	1608	NP_001026552.1	NP_001026552.1 MANSC domain-containing protein 1 precursor [Gallus gallus]	_	_	9031.ENSGALP00000022848	MANSC domain containing 1 	_	_	NOG42583	PF07502.11|MANEC|MANEC domain|ENSGALT00000058240|m.2171:39-126
ENSGALG00000038748	19.53060591	6.569222569	1.570486179	1.82E-46	5.83E-45	up	yes	17.72107716	19.96276985	20.90797071	7.009102366	6.361288556	6.337276785	23	2551024	2555961	+	RSRP1	protein_coding	--	--	--	--	--	1674	XP_417739.2	XP_417739.2 arginine/serine-rich protein 1 [Gallus gallus]	sp|Q9BUV0|RSRP1_HUMAN	sp|Q9BUV0|RSRP1_HUMAN Arginine/serine-rich protein 1 OS=Homo sapiens GN=RSRP1 PE=1 SV=2	_	_	_	_	_	PF17069.2|RSRP|Arginine/Serine-Rich protein 1|ENSGALT00000068027|m.5376:97-375
ENSGALG00000038768	4.323765623	20.60276833	-2.249845237	3.49E-66	2.05E-64	down	yes	4.91909629	3.560446112	4.491754466	22.0376565	20.68948049	19.08116801	14	2130706	2182145	+	FAM20C	protein_coding	GO:0006468|protein phosphorylation; GO:0030501|positive regulation of bone mineralization; GO:0031214|biomineral tissue development; GO:0036179|osteoclast maturation; GO:0040036|regulation of fibroblast growth factor receptor signaling pathway; GO:0043687|post-translational protein modification; GO:0044267|cellular protein metabolic process; GO:0045669|positive regulation of osteoblast differentiation; GO:0046034|ATP metabolic process; GO:0051174|regulation of phosphorus metabolic process; GO:0070166|enamel mineralization; GO:0071895|odontoblast differentiation; GO:0097187|dentinogenesis	GO:0005615|extracellular space; GO:0005788|endoplasmic reticulum lumen; GO:0005794|Golgi apparatus; GO:0070062|extracellular exosome	GO:0004674|protein serine/threonine kinase activity; GO:0005509|calcium ion binding; GO:0005524|ATP binding; GO:0030145|manganese ion binding	--	--	1671	XP_015149804.2	XP_015149804.2 extracellular serine/threonine protein kinase FAM20C [Gallus gallus]	sp|Q8IXL6|FA20C_HUMAN	sp|Q8IXL6|FA20C_HUMAN Extracellular serine/threonine protein kinase FAM20C OS=Homo sapiens GN=FAM20C PE=1 SV=2	9031.ENSGALP00000005755	"family with sequence similarity 20, member C"	_	KOG3829	_	"PF06702.9|Fam20C|Golgi casein kinase, C-terminal, Fam20|ENSGALT00000080528|m.9225:324-541"
ENSGALG00000038769	0.350196888	1.773099248	-2.307529385	1.83E-07	6.36E-07	down	yes	0.19174341	0.449876592	0.408970662	1.254956492	2.366015118	1.698326135	18	10539931	10546076	-	USH1G	protein_coding	GO:0007605|sensory perception of sound; GO:0042472|inner ear morphogenesis; GO:0045494|photoreceptor cell maintenance; GO:0050953|sensory perception of light stimulus; GO:0050957|equilibrioception; GO:0060113|inner ear receptor cell differentiation; GO:0060122|inner ear receptor cell stereocilium organization	GO:0001917|photoreceptor inner segment; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0015629|actin cytoskeleton; GO:0016020|membrane; GO:0032391|photoreceptor connecting cilium; GO:0036064|ciliary basal body	GO:0030507|spectrin binding; GO:0042803|protein homodimerization activity	ko:K21414|--	--	1374	XP_426242.2	XP_426242.2 Usher syndrome type-1G protein [Gallus gallus]	sp|Q80T11|USH1G_MOUSE	sp|Q80T11|USH1G_MOUSE Usher syndrome type-1G protein homolog OS=Mus musculus GN=Ush1g PE=1 SV=1	9031.ENSGALP00000012601	Usher syndrome 1G (autosomal recessive)	COG0666	KOG0504	_	PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000067050|m.13300:6-91;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000067050|m.13300:38-117;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000067050|m.13300:5-50;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000067050|m.13300:38-85;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000067050|m.13300:80-117;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000067050|m.13300:65-94;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000067050|m.13300:60-105;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000067050|m.13300:65-91;PF00536.27|SAM_1|SAM domain (Sterile alpha motif)|ENSGALT00000067050|m.13300:390-441
ENSGALG00000038789	3.632714065	1.06783928	1.756871686	1.65E-13	9.80E-13	up	yes	3.697620288	3.571350786	3.629171122	0.976271938	0.970243042	1.25700286	17	778807	781437	-	CLIC3	protein_coding	GO:0006821|chloride transport; GO:1902476|chloride transmembrane transport	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0016604|nuclear body; GO:0034707|chloride channel complex; GO:0070062|extracellular exosome	GO:0005244|voltage-gated ion channel activity; GO:0005254|chloride channel activity	ko:K05023|CLIC3	--	1482	XP_003642297.3	XP_003642297.3 chloride intracellular channel protein 3 [Gallus gallus]	sp|Q9D7P7|CLIC3_MOUSE	sp|Q9D7P7|CLIC3_MOUSE Chloride intracellular channel protein 3 OS=Mus musculus GN=Clic3 PE=1 SV=2	28377.ENSACAP00000007060	chloride intracellular channel 3	_	KOG1422	_	"PF13417.3|GST_N_3|Glutathione S-transferase, N-terminal domain|ENSGALT00000073089|m.11626:50-114;PF13410.3|GST_C_2|Glutathione S-transferase, C-terminal domain|ENSGALT00000073089|m.11626:157-235"
ENSGALG00000038848	2.029199916	7.541331924	-1.888727914	9.37E-26	1.21E-24	down	yes	2.429723144	1.677900984	1.979975621	7.927863081	8.145698697	6.550433993	13	10514513	10519859	+	MSX2	protein_coding	"GO:0002063|chondrocyte development; GO:0002076|osteoblast development; GO:0003148|outflow tract septum morphogenesis; GO:0003198|epithelial to mesenchymal transition involved in endocardial cushion formation; GO:0003416|endochondral bone growth; GO:0006351|transcription, DNA-templated; GO:0008285|negative regulation of cell population proliferation; GO:0009952|anterior/posterior pattern specification; GO:0023019|signal transduction involved in regulation of gene expression; GO:0030513|positive regulation of BMP signaling pathway; GO:0032792|negative regulation of CREB transcription factor activity; GO:0035115|embryonic forelimb morphogenesis; GO:0035116|embryonic hindlimb morphogenesis; GO:0035313|wound healing, spreading of epidermal cells; GO:0035880|embryonic nail plate morphogenesis; GO:0043066|negative regulation of apoptotic process; GO:0045599|negative regulation of fat cell differentiation; GO:0045617|negative regulation of keratinocyte differentiation; GO:0045669|positive regulation of osteoblast differentiation; GO:0048863|stem cell differentiation; GO:0051795|positive regulation of timing of catagen; GO:0060346|bone trabecula formation; GO:0060364|frontal suture morphogenesis; GO:0061312|BMP signaling pathway involved in heart development; GO:0071392|cellular response to estradiol stimulus; GO:0090427|activation of meiosis; GO:2000678|negative regulation of transcription regulatory region DNA binding; GO:2001055|positive regulation of mesenchymal cell apoptotic process"	GO:0005829|cytosol; GO:0016607|nuclear speck	"GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding; GO:0001227|DNA-binding transcription repressor activity, RNA polymerase II-specific; GO:0003712|transcription coregulator activity; GO:0008134|transcription factor binding"	ko:K09341|MSX	ko05166|HTLV-I infection	1865	NP_989890.1	NP_989890.1 homeobox protein MSX-2 [Gallus gallus]	sp|P28362|MSX2_CHICK	sp|P28362|MSX2_CHICK Homeobox protein MSX-2 OS=Gallus gallus GN=MSX2 PE=2 SV=2	9031.ENSGALP00000004650	Homeobox protein MSX-2 (CHOX-8)(GHox-8); Morphogenetic role	_	KOG0492	_	PF00046.26|Homeobox|Homeobox domain|ENSGALT00000065242|m.8621:135-191
ENSGALG00000038896	2.248459434	0.814671827	1.453446973	1.12E-10	5.27E-10	up	yes	2.012115109	2.785116618	1.948146574	0.877101197	0.818095877	0.748818406	23	5366529	5372344	+	ENSGALG00000038896	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated"	GO:0005634|nucleus	GO:0003677|DNA binding; GO:0046872|metal ion binding	ko:K10495|ZBTB8	--	2559	XP_015153342.1	XP_015153342.1 zinc finger and BTB domain-containing protein 8A [Gallus gallus]	sp|Q0VCJ6|ZBT8A_BOVIN	sp|Q0VCJ6|ZBT8A_BOVIN Zinc finger and BTB domain-containing protein 8A OS=Bos taurus GN=ZBTB8A PE=2 SV=1	59729.ENSTGUP00000017991	similar to Zbtb8a protein	COG5048	KOG1721	_	PF00651.28|BTB|BTB/POZ domain|ENSGALT00000053140|m.5760:14-121;PF11822.5|DUF3342|Domain of unknown function (DUF3342)|ENSGALT00000053140|m.5760:31-114
ENSGALG00000038902	6.240827997	41.39283114	-2.727610213	1.16E-190	9.32E-188	down	yes	6.583221128	5.755058727	6.384204137	39.9821831	40.42651636	43.76979397	26	238271	241790	-	PIM1	protein_coding	GO:0006468|protein phosphorylation; GO:0006915|apoptotic process; GO:0007049|cell cycle; GO:0007275|multicellular organism development; GO:0007346|regulation of mitotic cell cycle; GO:0008283|cell population proliferation; GO:0030212|hyaluronan metabolic process; GO:0043066|negative regulation of apoptotic process; GO:0043433|negative regulation of DNA-binding transcription factor activity; GO:0046777|protein autophosphorylation; GO:0060045|positive regulation of cardiac muscle cell proliferation; GO:0070561|vitamin D receptor signaling pathway; GO:1905062|positive regulation of cardioblast proliferation	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005730|nucleolus; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005886|plasma membrane	GO:0004674|protein serine/threonine kinase activity; GO:0005524|ATP binding; GO:0008134|transcription factor binding; GO:0030145|manganese ion binding; GO:0043024|ribosomal small subunit binding	ko:K04702|PIM1	ko04630|Jak-STAT signaling pathway; ko04933|AGE-RAGE signaling pathway in diabetic complications; ko05206|MicroRNAs in cancer; ko05221|Acute myeloid leukemia	2081	XP_003642760.1	XP_003642760.1 serine/threonine-protein kinase pim-1 isoform X1 [Gallus gallus]	sp|P11309|PIM1_HUMAN	sp|P11309|PIM1_HUMAN Serine/threonine-protein kinase pim-1 OS=Homo sapiens GN=PIM1 PE=1 SV=3	28377.ENSACAP00000016506	pim-1 oncogene	COG0515	KOG0583	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000067485|m.7461:74-326;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000067485|m.7461:78-322;PF14531.3|Kinase-like|Kinase-like|ENSGALT00000067485|m.7461:163-292;PF06293.11|Kdo|Lipopolysaccharide kinase (Kdo/WaaP) family|ENSGALT00000067485|m.7461:153-226
ENSGALG00000038913	3.31272725	6.873984882	-1.050876057	6.68E-10	2.93E-09	down	yes	3.124104916	3.943604177	2.870472656	6.917496668	6.572733929	7.131724051	5	19507937	19608245	+	LDLRAD3	protein_coding	--	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	--	--	--	1336	KFW91017.1	"KFW91017.1 Low-density lipoprotein receptor class A domain-containing protein 3, partial [Phalacrocorax carbo]"	sp|A4IHY6|LRAD3_XENTR	sp|A4IHY6|LRAD3_XENTR Low-density lipoprotein receptor class A domain-containing protein 3 OS=Xenopus tropicalis GN=ldlrad3 PE=2 SV=1	_	_	_	_	_	PF00057.15|Ldl_recept_a|Low-density lipoprotein receptor domain class A|ENSGALT00000098828|m.2887:47-83;PF00057.15|Ldl_recept_a|Low-density lipoprotein receptor domain class A|ENSGALT00000098828|m.2887:90-124
ENSGALG00000038969	73.47222931	22.79015738	1.688351613	5.52E-42	1.52E-40	up	yes	73.28179527	71.84682431	75.28806837	27.2470645	18.95985261	22.16355504	1	48088780	48089278	+	HIST2H3L	protein_coding	GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006334|nucleosome assembly	GO:0000786|nucleosome; GO:0005634|nucleus	GO:0031492|nucleosomal DNA binding; GO:0046982|protein heterodimerization activity	ko:K11253|H3	ko05034|Alcoholism; ko05202|Transcriptional misregulation in cancer; ko05322|Systemic lupus erythematosus	499	XP_015714064.1	XP_015714064.1 PREDICTED: uncharacterized protein LOC107311753 [Coturnix japonica]	sp|P84227|H32_BOVIN	sp|P84227|H32_BOVIN Histone H3.2 OS=Bos taurus PE=1 SV=2	9258.ENSOANP00000000374	annotation not avaliable	COG2036	KOG1745	_	PF00125.21|Histone|Core histone H2A/H2B/H3/H4|ENSGALT00000058115|m.1173:13-144
ENSGALG00000039040	3.345939078	6.761105289	-1.012674827	8.16E-07	2.64E-06	down	yes	3.002692822	4.40315397	2.631970444	7.13260125	6.507145403	6.643569215	3	3491748	3495862	-	PAX1	protein_coding	"GO:0001501|skeletal system development; GO:0001756|somitogenesis; GO:0006355|regulation of transcription, DNA-templated; GO:0007389|pattern specification process; GO:0008283|cell population proliferation; GO:0009887|animal organ morphogenesis; GO:0043367|CD4-positive, alpha-beta T cell differentiation; GO:0043374|CD8-positive, alpha-beta T cell differentiation; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0048538|thymus development; GO:0060017|parathyroid gland development; GO:0060349|bone morphogenesis; GO:0061056|sclerotome development"	GO:0005634|nucleus; GO:0005667|transcription factor complex	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003700|DNA-binding transcription factor activity"	ko:K09382|PAX1_9	--	1281	XP_015138914.2	XP_015138914.2 paired box protein Pax-1 [Gallus gallus]	sp|P09084|PAX1_MOUSE	sp|P09084|PAX1_MOUSE Paired box protein Pax-1 OS=Mus musculus GN=Pax1 PE=1 SV=4	_	_	_	_	_	PF00292.15|PAX|'Paired box' domain|ENSGALT00000079315|m.10640:78-201;PF13384.3|HTH_23|Homeodomain-like domain|ENSGALT00000079315|m.10640:98-137
ENSGALG00000039092	5.735907735	1.593225163	1.841557769	5.09E-15	3.41E-14	up	yes	7.191091565	4.505603369	5.51102827	1.786883945	1.516826896	1.475964649	2	45701178	45771546	+	STAC	protein_coding	GO:0035556|intracellular signal transduction	GO:0005737|cytoplasm	GO:0046872|metal ion binding	--	--	1209	XP_426020.3	XP_426020.3 SH3 and cysteine-rich domain-containing protein isoform X1 [Gallus gallus]	sp|A0JNJ1|STAC_BOVIN	sp|A0JNJ1|STAC_BOVIN SH3 and cysteine-rich domain-containing protein OS=Bos taurus GN=STAC PE=2 SV=1	9031.ENSGALP00000019662	SH3 and cysteine rich domain	_	KOG1843	_	PF16664.2|STAC2_u1|Unstructured on SH3 and cysteine-rich domain-containing protein 2|ENSGALT00000057423|m.613:168-267;PF14604.3|SH3_9|Variant SH3 domain|ENSGALT00000057423|m.613:292-340;PF00018.25|SH3_1|SH3 domain|ENSGALT00000057423|m.613:291-336;PF07653.14|SH3_2|Variant SH3 domain|ENSGALT00000057423|m.613:290-340;PF07653.14|SH3_2|Variant SH3 domain|ENSGALT00000057423|m.613:349-400;PF00130.19|C1_1|Phorbol esters/diacylglycerol binding domain (C1 domain)|ENSGALT00000057423|m.613:110-156
ENSGALG00000039169	17.10209403	41.77340729	-1.287913828	8.02E-67	4.77E-65	down	yes	16.74523697	16.85132042	17.70972472	40.6793898	43.88291012	40.75792196	2	45962364	45978539	+	MLH1	protein_coding	GO:0000289|nuclear-transcribed mRNA poly(A) tail shortening; GO:0000712|resolution of meiotic recombination intermediates; GO:0006298|mismatch repair; GO:0006303|double-strand break repair via nonhomologous end joining; GO:0007060|male meiosis chromosome segregation; GO:0007129|synapsis; GO:0007283|spermatogenesis; GO:0008630|intrinsic apoptotic signaling pathway in response to DNA damage; GO:0016321|female meiosis chromosome segregation; GO:0016446|somatic hypermutation of immunoglobulin genes; GO:0043060|meiotic metaphase I plate congression; GO:0045141|meiotic telomere clustering; GO:0045190|isotype switching; GO:0045950|negative regulation of mitotic recombination; GO:0048298|positive regulation of isotype switching to IgA isotypes; GO:0048304|positive regulation of isotype switching to IgG isotypes; GO:0048477|oogenesis; GO:0051257|meiotic spindle midzone assembly	GO:0000795|synaptonemal complex; GO:0001673|male germ cell nucleus; GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005712|chiasma; GO:0005715|late recombination nodule; GO:0016020|membrane; GO:0032389|MutLalpha complex	GO:0003682|chromatin binding; GO:0005524|ATP binding; GO:0016887|ATPase activity; GO:0032137|guanine/thymine mispair binding	ko:K08734|MLH1	ko01524|Platinum drug resistance; ko03430|Mismatch repair; ko03460|Fanconi anemia pathway; ko05200|Pathways in cancer; ko05210|Colorectal cancer; ko05213|Endometrial cancer	2382	XP_418828.1	XP_418828.1 DNA mismatch repair protein Mlh1 isoform X1 [Gallus gallus]	sp|P40692|MLH1_HUMAN	sp|P40692|MLH1_HUMAN DNA mismatch repair protein Mlh1 OS=Homo sapiens GN=MLH1 PE=1 SV=1	9031.ENSGALP00000019676	"mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)"	COG0323	KOG1979	_	"PF16413.2|Mlh1_C|DNA mismatch repair protein Mlh1 C-terminus|ENSGALT00000068346|m.620:503-757;PF01119.16|DNA_mis_repair|DNA mismatch repair protein, C-terminal domain|ENSGALT00000068346|m.620:216-334;PF13589.3|HATPase_c_3|Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase|ENSGALT00000068346|m.620:29-131;PF02518.23|HATPase_c|Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase|ENSGALT00000068346|m.620:30-92"
ENSGALG00000039173	1.94362738	4.705620342	-1.271292246	5.84E-10	2.57E-09	down	yes	2.038832952	1.70509076	2.086958426	5.40427184	4.397132691	4.315456494	10	15117634	15137240	-	RGMA	protein_coding	GO:0030509|BMP signaling pathway; GO:0048681|negative regulation of axon regeneration	GO:0005886|plasma membrane; GO:0031225|anchored component of membrane	GO:0015026|coreceptor activity	ko:K06847|RGM	--	1640	NP_989868.2	NP_989868.2 repulsive guidance molecule A precursor [Gallus gallus]	sp|Q8JG54|RGMA_CHICK	sp|Q8JG54|RGMA_CHICK Repulsive guidance molecule A OS=Gallus gallus GN=RGMA PE=1 SV=1	9031.ENSGALP00000011271	Repulsive guidance molecule A Precursor ; Acts as an axon-specific repulsive guidance molecu [...] 	_	_	NOG87951	PF06534.10|RGM_C|Repulsive guidance molecule (RGM) C-terminus|ENSGALT00000077053|m.5703:209-388;PF06535.9|RGM_N|Repulsive guidance molecule (RGM) N-terminus|ENSGALT00000077053|m.5703:32-204
ENSGALG00000039206	3.653326616	10.5451292	-1.526717998	4.07E-34	7.85E-33	down	yes	3.706589652	3.127668788	4.125721408	11.81487175	9.926706545	9.893809291	22	3788778	3793564	-	ARID5A	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0002062|chondrocyte differentiation; GO:0006351|transcription, DNA-templated; GO:0035066|positive regulation of histone acetylation; GO:0045087|innate immune response; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0071222|cellular response to lipopolysaccharide; GO:0071391|cellular response to estrogen stimulus; GO:1902715|positive regulation of interferon-gamma secretion; GO:1904469|positive regulation of tumor necrosis factor secretion; GO:1905078|positive regulation of interleukin-17 secretion; GO:2000318|positive regulation of T-helper 17 type immune response; GO:2000556|positive regulation of T-helper 1 cell cytokine production; GO:2000778|positive regulation of interleukin-6 secretion"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005667|transcription factor complex; GO:0005730|nucleolus	GO:0003682|chromatin binding; GO:0003714|transcription corepressor activity; GO:0008134|transcription factor binding; GO:0030331|estrogen receptor binding; GO:0035613|RNA stem-loop binding; GO:0043565|sequence-specific DNA binding; GO:0044212|transcription regulatory region DNA binding; GO:0046965|retinoid X receptor binding; GO:0046966|thyroid hormone receptor binding; GO:0050681|androgen receptor binding	--	--	2587	XP_015152937.2	XP_015152937.2 AT-rich interactive domain-containing protein 5A [Gallus gallus]	sp|Q3U108|ARI5A_MOUSE	sp|Q3U108|ARI5A_MOUSE AT-rich interactive domain-containing protein 5A OS=Mus musculus GN=Arid5a PE=1 SV=1	9031.ENSGALP00000029146	AT rich interactive domain 5A (MRF1-like)	_	KOG2744	_	PF01388.18|ARID|ARID/BRIGHT DNA binding domain|ENSGALT00000102471|m.4916:63-148
ENSGALG00000039209	3.082179909	1.098278981	1.480303172	4.12E-08	1.53E-07	up	yes	3.432094432	3.671490181	2.142955113	1.301557874	0.778825051	1.214454018	1	34002232	34044011	-	WIF1	protein_coding	GO:0007165|signal transduction; GO:0007275|multicellular organism development; GO:0016055|Wnt signaling pathway; GO:0030178|negative regulation of Wnt signaling pathway; GO:0045600|positive regulation of fat cell differentiation	GO:0005576|extracellular region	GO:0017147|Wnt-protein binding	ko:K01691|WIF1	ko04310|Wnt signaling pathway	1873	NP_001186536.2	NP_001186536.2 wnt inhibitory factor 1 precursor [Gallus gallus]	sp|Q9Y5W5|WIF1_HUMAN	sp|Q9Y5W5|WIF1_HUMAN Wnt inhibitory factor 1 OS=Homo sapiens GN=WIF1 PE=1 SV=3	9031.ENSGALP00000016025	WNT inhibitory factor 1	_	KOG1225	_	PF02019.15|WIF|WIF domain|ENSGALT00000063712|m.833:47-181;PF12661.4|hEGF|Human growth factor-like EGF|ENSGALT00000063712|m.833:206-218;PF12661.4|hEGF|Human growth factor-like EGF|ENSGALT00000063712|m.833:239-250;PF12661.4|hEGF|Human growth factor-like EGF|ENSGALT00000063712|m.833:270-282;PF12661.4|hEGF|Human growth factor-like EGF|ENSGALT00000063712|m.833:334-346
ENSGALG00000039228	39.6863117	100.5031218	-1.340306981	1.63E-66	9.67E-65	down	yes	42.43207237	37.80002825	38.82683448	108.977588	93.82103879	98.71073846	5	28553320	28555369	+	ZFP36L1	protein_coding	"GO:0000165|MAPK cascade; GO:0000288|nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0001570|vasculogenesis; GO:0003342|proepicardium development; GO:0006397|mRNA processing; GO:0006915|apoptotic process; GO:0007507|heart development; GO:0008283|cell population proliferation; GO:0009611|response to wounding; GO:0010468|regulation of gene expression; GO:0010837|regulation of keratinocyte proliferation; GO:0014065|phosphatidylinositol 3-kinase signaling; GO:0021915|neural tube development; GO:0031086|nuclear-transcribed mRNA catabolic process, deadenylation-independent decay; GO:0031440|regulation of mRNA 3'-end processing; GO:0032869|cellular response to insulin stimulus; GO:0033077|T cell differentiation in thymus; GO:0035264|multicellular organism growth; GO:0038066|p38MAPK cascade; GO:0043488|regulation of mRNA stability; GO:0043491|protein kinase B signaling; GO:0044344|cellular response to fibroblast growth factor stimulus; GO:0045577|regulation of B cell differentiation; GO:0045600|positive regulation of fat cell differentiation; GO:0045616|regulation of keratinocyte differentiation; GO:0045647|negative regulation of erythrocyte differentiation; GO:0045657|positive regulation of monocyte differentiation; GO:0045661|regulation of myoblast differentiation; GO:0048382|mesendoderm development; GO:0051028|mRNA transport; GO:0060710|chorio-allantoic fusion; GO:0060712|spongiotrophoblast layer development; GO:0061158|3'-UTR-mediated mRNA destabilization; GO:0070371|ERK1 and ERK2 cascade; GO:0071320|cellular response to cAMP; GO:0071356|cellular response to tumor necrosis factor; GO:0071364|cellular response to epidermal growth factor stimulus; GO:0071375|cellular response to peptide hormone stimulus; GO:0071385|cellular response to glucocorticoid stimulus; GO:0071456|cellular response to hypoxia; GO:0071472|cellular response to salt stress; GO:0071560|cellular response to transforming growth factor beta stimulus; GO:0072091|regulation of stem cell proliferation; GO:0097403|cellular response to raffinose; GO:1900153|positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:1901991|negative regulation of mitotic cell cycle phase transition; GO:1902172|regulation of keratinocyte apoptotic process; GO:1904582|positive regulation of intracellular mRNA localization; GO:1904628|cellular response to phorbol 13-acetate 12-myristate"	GO:0000932|P-body; GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:1990904|ribonucleoprotein complex	GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity; GO:0003723|RNA binding; GO:0003729|mRNA binding; GO:0035925|mRNA 3'-UTR AU-rich region binding; GO:0046872|metal ion binding; GO:0071889|14-3-3 protein binding	ko:K18753|ZFP36L	--	1623	NP_001305960.1	NP_001305960.1 mRNA decay activator protein ZFP36L1 [Gallus gallus]	sp|Q07352|TISB_HUMAN	sp|Q07352|TISB_HUMAN mRNA decay activator protein ZFP36L1 OS=Homo sapiens GN=ZFP36L1 PE=1 SV=1	_	_	_	_	_	"PF04553.9|Tis11B_N|Tis11B like protein, N terminus|ENSGALT00000060504|m.3234:28-130;PF00642.21|zf-CCCH|Zinc finger C-x8-C-x5-C-x3-H type (and similar)|ENSGALT00000060504|m.3234:140-165;PF00642.21|zf-CCCH|Zinc finger C-x8-C-x5-C-x3-H type (and similar)|ENSGALT00000060504|m.3234:178-202"
ENSGALG00000039239	3.056767581	1.224237082	1.313099288	1.67E-07	5.82E-07	up	yes	2.267209172	4.061110236	2.841983336	1.165862218	1.396085718	1.110763312	15	409259	417626	-	SERPIND1	protein_coding	GO:0007596|blood coagulation	GO:0005615|extracellular space; GO:0070062|extracellular exosome	GO:0004867|serine-type endopeptidase inhibitor activity; GO:0008201|heparin binding	"ko:K03912|SERPIND1,HCF2"	ko04610|Complement and coagulation cascades	1836	XP_001232767.1	XP_001232767.1 heparin cofactor 2 [Gallus gallus]	sp|P49182|HEP2_MOUSE	sp|P49182|HEP2_MOUSE Heparin cofactor 2 OS=Mus musculus GN=Serpind1 PE=1 SV=1	_	_	_	_	_	PF00079.17|Serpin|Serpin (serine protease inhibitor)|ENSGALT00000063276|m.10263:119-485
ENSGALG00000039264	0.271729038	1.431858952	-2.355549863	3.60E-13	2.09E-12	down	yes	0.17735136	0.27307176	0.364763995	1.614391506	1.255538484	1.425646865	2	141829134	141867820	-	SLA	protein_coding	GO:0007169|transmembrane receptor protein tyrosine kinase signaling pathway; GO:0016477|cell migration; GO:0030154|cell differentiation; GO:0038083|peptidyl-tyrosine autophosphorylation; GO:0042127|regulation of cell population proliferation; GO:0045087|innate immune response	GO:0005768|endosome; GO:0031234|extrinsic component of cytoplasmic side of plasma membrane	GO:0004715|non-membrane spanning protein tyrosine kinase activity; GO:0005070|SH3/SH2 adaptor activity; GO:0005102|signaling receptor binding	--	--	2621	XP_015138563.1	XP_015138563.1 src-like-adapter isoform X1 [Gallus gallus]	sp|Q13239|SLAP1_HUMAN	sp|Q13239|SLAP1_HUMAN Src-like-adapter OS=Homo sapiens GN=SLA PE=1 SV=3	9031.ENSGALP00000026128	Src-like-adaptor 	_	KOG0197	_	PF00017.21|SH2|SH2 domain|ENSGALT00000099487|m.2571:88-164;PF00018.25|SH3_1|SH3 domain|ENSGALT00000099487|m.2571:33-77
ENSGALG00000039307	0.550798877	0.087867942	2.518575186	1.24E-07	4.40E-07	up	yes	0.463557969	0.704938589	0.483900073	0.038748109	0.129013858	0.09584186	10	9323769	9344819	+	GNB5	protein_coding	GO:0006457|protein folding; GO:0007165|signal transduction; GO:0007212|dopamine receptor signaling pathway; GO:0043547|positive regulation of GTPase activity; GO:1901386|negative regulation of voltage-gated calcium channel activity	GO:0001750|photoreceptor outer segment; GO:0001917|photoreceptor inner segment; GO:0005634|nucleus; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0043209|myelin sheath; GO:1902773|GTPase activator complex	GO:0003924|GTPase activity; GO:0005096|GTPase activator activity; GO:0031682|G-protein gamma-subunit binding; GO:0051087|chaperone binding	ko:K04539|GNB5	ko04014|Ras signaling pathway; ko04062|Chemokine signaling pathway; ko04151|PI3K-Akt signaling pathway; ko04371|Apelin signaling pathway; ko04713|Circadian entrainment; ko04723|Retrograde endocannabinoid signaling; ko04724|Glutamatergic synapse; ko04725|Cholinergic synapse; ko04726|Serotonergic synapse; ko04727|GABAergic synapse; ko04728|Dopaminergic synapse; ko05032|Morphine addiction; ko05034|Alcoholism; ko05200|Pathways in cancer	3069	NP_001280171.1	NP_001280171.1 guanine nucleotide-binding protein subunit beta-5 [Gallus gallus]	sp|O14775|GNB5_HUMAN	sp|O14775|GNB5_HUMAN Guanine nucleotide-binding protein subunit beta-5 OS=Homo sapiens GN=GNB5 PE=1 SV=2	_	_	_	_	_	"PF00400.29|WD40|WD domain, G-beta repeat|ENSGALT00000051268|m.5484:63-99;PF00400.29|WD40|WD domain, G-beta repeat|ENSGALT00000051268|m.5484:193-233;PF00400.29|WD40|WD domain, G-beta repeat|ENSGALT00000051268|m.5484:237-275;PF00400.29|WD40|WD domain, G-beta repeat|ENSGALT00000051268|m.5484:295-319;PF00400.29|WD40|WD domain, G-beta repeat|ENSGALT00000051268|m.5484:326-360"
ENSGALG00000039334	0.668935015	2.814401471	-2.056599776	5.75E-15	3.82E-14	down	yes	0.851573157	0.526815713	0.628416175	2.772750093	2.946948123	2.723506197	5	939736	975245	-	ENSGALG00000039334	protein_coding	--	--	GO:0003723|RNA binding	--	--	1980	XP_004941352.2	XP_004941352.2 coiled-coil domain-containing protein 9B isoform X1 [Gallus gallus]	sp|Q6ZUT6|CO052_HUMAN	sp|Q6ZUT6|CO052_HUMAN Uncharacterized protein C15orf52 OS=Homo sapiens GN=C15orf52 PE=1 SV=1	9031.ENSGALP00000007594	chromosome 15 open reading frame 52	_	_	NOG47494	PF15266.3|DUF4594|Domain of unknown function (DUF4594)|ENSGALT00000052081|m.2186:135-293
ENSGALG00000039356	0.906971798	4.977796165	-2.443453239	1.33E-05	3.68E-05	down	yes	0.301206683	1.104225008	1.315483703	5.279703024	4.153531494	5.500153978	24	269631	274676	+	HEPACAM	protein_coding	GO:0007050|cell cycle arrest; GO:0007155|cell adhesion; GO:0034613|cellular protein localization; GO:0040008|regulation of growth	GO:0005737|cytoplasm; GO:0005911|cell-cell junction; GO:0016021|integral component of membrane; GO:0030424|axon	--	--	--	2460	XP_024999011.1	XP_024999011.1 hepatocyte cell adhesion molecule isoform X5 [Gallus gallus]	sp|A4FUY1|HECAM_BOVIN	sp|A4FUY1|HECAM_BOVIN Hepatocyte cell adhesion molecule OS=Bos taurus GN=HEPACAM PE=2 SV=1	9031.ENSGALP00000000573	hepatocyte cell adhesion molecule	_	_	NOG80335	PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000107965|m.5989:159-233;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000107965|m.5989:174-247;PF07686.14|V-set|Immunoglobulin V-set domain|ENSGALT00000107965|m.5989:55-153;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000107965|m.5989:162-247
ENSGALG00000039380	5.992662783	12.31481534	-1.037891503	3.63E-35	7.28E-34	down	yes	5.60468737	6.183365489	6.189935491	11.48271266	13.02532681	12.43640656	4	69696354	69792663	-	TBC1D1	protein_coding	GO:0006886|intracellular protein transport; GO:0031338|regulation of vesicle fusion; GO:0032880|regulation of protein localization; GO:0061024|membrane organization; GO:0090630|activation of GTPase activity	GO:0005622|intracellular; GO:0005634|nucleus; GO:0005829|cytosol; GO:0012505|endomembrane system	GO:0005096|GTPase activator activity; GO:0017137|Rab GTPase binding	ko:K18341|TBC1D1	ko04152|AMPK signaling pathway	5674	NP_001254502.1	NP_001254502.1 TBC1 domain family member 1 [Gallus gallus]	sp|Q86TI0|TBCD1_HUMAN	sp|Q86TI0|TBCD1_HUMAN TBC1 domain family member 1 OS=Homo sapiens GN=TBC1D1 PE=1 SV=2	_	_	_	_	_	PF00566.15|RabGAP-TBC|Rab-GTPase-TBC domain|ENSGALT00000079545|m.1233:816-1026;PF11830.5|DUF3350|Domain of unknown function (DUF3350)|ENSGALT00000079545|m.1233:702-757;PF00640.20|PID|Phosphotyrosine interaction domain (PTB/PID)|ENSGALT00000079545|m.1233:309-402
ENSGALG00000039403	0.245170271	0.867318143	-1.781639846	3.98E-07	1.33E-06	down	yes	0.204962345	0.254317579	0.27623089	1.061555574	0.84803175	0.692367105	1	21072336	21395611	+	GRM8	protein_coding	"GO:0007196|adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway; GO:0007601|visual perception; GO:0051966|regulation of synaptic transmission, glutamatergic"	GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0042734|presynaptic membrane	GO:0004930|G protein-coupled receptor activity; GO:0008066|glutamate receptor activity	ko:K04608|GRM6_7_8	ko04072|Phospholipase D signaling pathway; ko04080|Neuroactive ligand-receptor interaction; ko04724|Glutamatergic synapse	3342	XP_004937573.1	XP_004937573.1 metabotropic glutamate receptor 8 isoform X1 [Gallus gallus]	sp|O00222|GRM8_HUMAN	sp|O00222|GRM8_HUMAN Metabotropic glutamate receptor 8 OS=Homo sapiens GN=GRM8 PE=2 SV=2	9031.ENSGALP00000014160	"glutamate receptor, metabotropic 8"	_	KOG1056	_	PF01094.25|ANF_receptor|Receptor family ligand binding region|ENSGALT00000065046|m.603:75-478;PF00003.19|7tm_3|7 transmembrane sweet-taste receptor of 3 GCPR|ENSGALT00000065046|m.603:595-840;PF07562.11|NCD3G|Nine Cysteines Domain of family 3 GPCR|ENSGALT00000065046|m.603:512-562
ENSGALG00000039447	1.458362237	0.261162049	2.436980736	1.98E-11	9.95E-11	up	yes	1.280789616	1.528728468	1.565568626	0.313708545	0.259163895	0.210613707	27	7349549	7359237	-	KRT23	protein_coding	--	GO:0005882|intermediate filament	GO:0005198|structural molecule activity	ko:K07604|KRT1	--	1769	XP_418167.4	"XP_418167.4 keratin, type I cytoskeletal 23 [Gallus gallus]"	sp|Q99PS0|K1C23_MOUSE	"sp|Q99PS0|K1C23_MOUSE Keratin, type I cytoskeletal 23 OS=Mus musculus GN=Krt23 PE=1 SV=1"	9031.ENSGALP00000030684	keratin 23 (histone deacetylase inducible)	_	KOG0508	_	PF00038.18|Filament|Intermediate filament protein|ENSGALT00000057873|m.9307:96-404
ENSGALG00000039535	2.408436388	5.424855901	-1.168167193	3.93E-18	3.28E-17	down	yes	2.349539317	2.750422041	2.125347808	5.769644464	5.00519337	5.499729869	9	4934110	4943942	-	D2HGDH	protein_coding	GO:0006103|2-oxoglutarate metabolic process; GO:0010042|response to manganese ion; GO:0010043|response to zinc ion; GO:0019516|lactate oxidation; GO:0022904|respiratory electron transport chain; GO:0032025|response to cobalt ion; GO:0044267|cellular protein metabolic process	GO:0005739|mitochondrion; GO:0005759|mitochondrial matrix	GO:0004458|D-lactate dehydrogenase (cytochrome) activity; GO:0051990|(R)-2-hydroxyglutarate dehydrogenase activity; GO:0071949|FAD binding	--	--	3947	XP_015132607.1	"XP_015132607.1 D-2-hydroxyglutarate dehydrogenase, mitochondrial [Gallus gallus]"	sp|Q8N465|D2HDH_HUMAN	"sp|Q8N465|D2HDH_HUMAN D-2-hydroxyglutarate dehydrogenase, mitochondrial OS=Homo sapiens GN=D2HGDH PE=1 SV=3"	9031.ENSGALP00000010244	D-2-hydroxyglutarate dehydrogenase	COG0277	KOG1232	_	"PF02913.16|FAD-oxidase_C|FAD linked oxidases, C-terminal domain|ENSGALT00000059515|m.8500:295-535;PF01565.20|FAD_binding_4|FAD binding domain|ENSGALT00000059515|m.8500:122-258"
ENSGALG00000039536	3.055380265	11.3571655	-1.890734592	2.05E-18	1.75E-17	down	yes	2.296791063	4.193513112	2.675836618	13.23004501	11.7910309	9.050420592	2	108494837	108497336	+	C2H8ORF22	protein_coding	GO:0001708|cell fate specification; GO:0031017|exocrine pancreas development	--	--	--	--	1170	XP_021244373.1	XP_021244373.1 pancreatic progenitor cell differentiation and proliferation factor-like protein [Numida meleagris]	sp|Q8WWR9|PDPFL_HUMAN	sp|Q8WWR9|PDPFL_HUMAN Pancreatic progenitor cell differentiation and proliferation factor-like protein OS=Homo sapiens GN=PPDPFL PE=3 SV=1	9031.ENSGALP00000040605	chromosome 8 open reading frame 22	_	_	NOG72558	PF15060.3|PPDFL|Differentiation and proliferation regulator|ENSGALT00000078058|m.1750:29-103
ENSGALG00000039571	4.201386242	1.865620319	1.166927383	0.000528177	0.001158041	up	yes	5.170265597	2.452898558	4.98099457	1.916186243	1.954608449	1.726066265	33	5425817	5426967	+	PRPH	protein_coding	--	GO:0005882|intermediate filament; GO:0016020|membrane; GO:0045098|type III intermediate filament; GO:0070062|extracellular exosome	GO:0005198|structural molecule activity	--	--	693	POI19481.1	POI19481.1 hypothetical protein CIB84_016774 [Bambusicola thoracicus]	sp|P41219|PERI_HUMAN	sp|P41219|PERI_HUMAN Peripherin OS=Homo sapiens GN=PRPH PE=1 SV=2	_	_	_	_	_	PF00038.18|Filament|Intermediate filament protein|ENSGALT00000061082|m.15121:5-228
ENSGALG00000039583	5.250635909	15.09085821	-1.521321434	2.29E-49	8.10E-48	down	yes	4.985935566	4.916715063	5.849257098	14.1737018	15.56923038	15.52964246	12	15882966	15968266	+	cmi9	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006355|regulation of transcription, DNA-templated; GO:0007275|multicellular organism development; GO:0010628|positive regulation of gene expression; GO:0016925|protein sumoylation; GO:0030318|melanocyte differentiation; GO:0045893|positive regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0065003|protein-containing complex assembly; GO:2000144|positive regulation of DNA-templated transcription, initiation; GO:2001141|regulation of RNA biosynthetic process"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0032991|protein-containing complex	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0001227|DNA-binding transcription repressor activity, RNA polymerase II-specific; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0046983|protein dimerization activity; GO:0070888|E-box binding"	ko:K09455|MITF	ko04137|Mitophagy - animal; ko04380|Osteoclast differentiation; ko04916|Melanogenesis; ko05200|Pathways in cancer; ko05218|Melanoma	2863	XP_015148453.2	XP_015148453.2 microphthalmia-associated transcription factor isoform X2 [Gallus gallus]	sp|O75030|MITF_HUMAN	sp|O75030|MITF_HUMAN Microphthalmia-associated transcription factor OS=Homo sapiens GN=MITF PE=1 SV=2	9031.ENSGALP00000012434	microphthalmia-associated transcription factor 	_	KOG1318	_	PF15951.2|MITF_TFEB_C_3_N|MITF/TFEB/TFEC/TFE3 N-terminus|ENSGALT00000060140|m.8026:4-142;PF11851.5|DUF3371|Domain of unknown function (DUF3371)|ENSGALT00000060140|m.8026:339-463;PF00010.23|HLH|Helix-loop-helix DNA-binding domain|ENSGALT00000060140|m.8026:254-307
ENSGALG00000039606	12.8180791	4.461644998	1.520427592	1.91E-48	6.60E-47	up	yes	14.05313082	12.27208221	12.12902427	4.051419304	4.216829543	5.116686147	3	90980907	90987501	-	CLN8	protein_coding	GO:0001306|age-dependent response to oxidative stress; GO:0006644|phospholipid metabolic process; GO:0006672|ceramide metabolic process; GO:0007006|mitochondrial membrane organization; GO:0007040|lysosome organization; GO:0007399|nervous system development; GO:0007601|visual perception; GO:0007628|adult walking behavior; GO:0008203|cholesterol metabolic process; GO:0008306|associative learning; GO:0008344|adult locomotory behavior; GO:0008361|regulation of cell size; GO:0021522|spinal cord motor neuron differentiation; GO:0021523|somatic motor neuron differentiation; GO:0035176|social behavior; GO:0043066|negative regulation of apoptotic process; GO:0044257|cellular protein catabolic process; GO:0044265|cellular macromolecule catabolic process; GO:0044267|cellular protein metabolic process; GO:0045494|photoreceptor cell maintenance; GO:0050881|musculoskeletal movement; GO:0050884|neuromuscular process controlling posture; GO:0050885|neuromuscular process controlling balance; GO:0051935|glutamate reuptake; GO:0060041|retina development in camera-type eye; GO:0060052|neurofilament cytoskeleton organization	GO:0005739|mitochondrion; GO:0005783|endoplasmic reticulum; GO:0005789|endoplasmic reticulum membrane; GO:0005793|endoplasmic reticulum-Golgi intermediate compartment; GO:0016021|integral component of membrane; GO:0033116|endoplasmic reticulum-Golgi intermediate compartment membrane; GO:0098793|presynapse	--	ko:K12360|CLN8	--	4732	NP_001026258.2	NP_001026258.2 protein CLN8 [Gallus gallus]	sp|Q9QUK3|CLN8_MOUSE	sp|Q9QUK3|CLN8_MOUSE Protein CLN8 OS=Mus musculus GN=Cln8 PE=1 SV=1	_	_	_	_	_	_
ENSGALG00000039652	1.019441888	3.726457437	-1.859808696	2.49E-30	3.99E-29	down	yes	0.968435756	1.03008405	1.059805857	3.458050554	3.792366194	3.928955561	13	9145396	9152907	-	ENSGALG00000039652	protein_coding	GO:0007264|small GTPase mediated signal transduction; GO:0035023|regulation of Rho protein signal transduction; GO:0043547|positive regulation of GTPase activity	GO:0005737|cytoplasm	GO:0005089|Rho guanyl-nucleotide exchange factor activity	ko:K20710|ARHGEF37	--	3188	XP_025010778.1	XP_025010778.1 rho guanine nucleotide exchange factor 37 [Gallus gallus]	sp|A1IGU5|ARH37_HUMAN	sp|A1IGU5|ARH37_HUMAN Rho guanine nucleotide exchange factor 37 OS=Homo sapiens GN=ARHGEF37 PE=2 SV=2	9031.ENSGALP00000001903	Rho guanine nucleotide exchange factor (GEF) 37	_	KOG3519	_	PF00621.17|RhoGEF|RhoGEF domain|ENSGALT00000068368|m.8546:187-245;PF07653.14|SH3_2|Variant SH3 domain|ENSGALT00000068368|m.8547:200-255
ENSGALG00000039682	1.756058317	0.833771417	1.065608862	0.000100179	0.000245729	up	yes	1.935506985	1.419115403	1.913552564	0.650586654	0.716625134	1.134102463	1	359020	371025	+	HCLS1	protein_coding	GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0008284|positive regulation of cell population proliferation; GO:0009725|response to hormone; GO:0014068|positive regulation of phosphatidylinositol 3-kinase signaling; GO:0030041|actin filament polymerization; GO:0030218|erythrocyte differentiation; GO:0030833|regulation of actin filament polymerization; GO:0030854|positive regulation of granulocyte differentiation; GO:0033138|positive regulation of peptidyl-serine phosphorylation; GO:0042531|positive regulation of tyrosine phosphorylation of STAT protein; GO:0045651|positive regulation of macrophage differentiation; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0050731|positive regulation of peptidyl-tyrosine phosphorylation; GO:0051897|positive regulation of protein kinase B signaling; GO:0071345|cellular response to cytokine stimulus; GO:2000107|negative regulation of leukocyte apoptotic process	GO:0005634|nucleus; GO:0005667|transcription factor complex; GO:0005737|cytoplasm; GO:0005739|mitochondrion; GO:0005829|cytosol; GO:0005886|plasma membrane	GO:0001085|RNA polymerase II transcription factor binding; GO:0003779|actin binding; GO:0017124|SH3 domain binding; GO:0019901|protein kinase binding; GO:0044877|protein-containing complex binding	"ko:K06106|CTTN,EMS1"	ko04530|Tight junction; ko05100|Bacterial invasion of epithelial cells; ko05130|Pathogenic Escherichia coli infection; ko05131|Shigellosis; ko05205|Proteoglycans in cancer	2559	NP_001026572.1	NP_001026572.1 hematopoietic lineage cell-specific protein [Gallus gallus]	sp|P49710|HCLS1_MOUSE	sp|P49710|HCLS1_MOUSE Hematopoietic lineage cell-specific protein OS=Mus musculus GN=Hcls1 PE=1 SV=2	9031.ENSGALP00000015886	hematopoietic cell-specific Lyn substrate 1 	_	KOG3655	_	PF02218.12|HS1_rep|Repeat in HS1/Cortactin|ENSGALT00000053187|m.63:104-139;PF02218.12|HS1_rep|Repeat in HS1/Cortactin|ENSGALT00000053187|m.63:141-176;PF02218.12|HS1_rep|Repeat in HS1/Cortactin|ENSGALT00000053187|m.63:178-213;PF02218.12|HS1_rep|Repeat in HS1/Cortactin|ENSGALT00000053187|m.63:215-250;PF02218.12|HS1_rep|Repeat in HS1/Cortactin|ENSGALT00000053187|m.63:252-275;PF14604.3|SH3_9|Variant SH3 domain|ENSGALT00000053187|m.63:486-534;PF00018.25|SH3_1|SH3 domain|ENSGALT00000053187|m.63:485-530;PF07653.14|SH3_2|Variant SH3 domain|ENSGALT00000053187|m.63:485-534
ENSGALG00000039687	2.837615591	0.605780036	2.209267404	5.29E-10	2.35E-09	up	yes	4.006763113	2.274396537	2.231687122	0.59961352	0.800849761	0.416876828	13	12058552	12067941	-	NIPAL4	protein_coding	GO:0015693|magnesium ion transport	GO:0016020|membrane; GO:0016021|integral component of membrane	GO:0015095|magnesium ion transmembrane transporter activity	--	--	1197	XP_414566.3	XP_414566.3 magnesium transporter NIPA4 isoform X1 [Gallus gallus]	sp|Q0D2K0|NIPA4_HUMAN	sp|Q0D2K0|NIPA4_HUMAN Magnesium transporter NIPA4 OS=Homo sapiens GN=NIPAL4 PE=1 SV=3	_	_	_	_	_	PF05653.11|Mg_trans_NIPA|Magnesium transporter NIPA|ENSGALT00000051501|m.8780:58-350;PF00892.17|EamA|EamA-like transporter family|ENSGALT00000051501|m.8780:104-175
ENSGALG00000039710	9.439918325	19.3996856	-1.038402984	8.06E-35	1.59E-33	down	yes	9.825048292	8.698717336	9.795989347	19.62345879	17.63224711	20.94335089	33	5847783	5910234	+	HDAC7	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0001570|vasculogenesis; GO:0006351|transcription, DNA-templated; GO:0007043|cell-cell junction assembly; GO:0032703|negative regulation of interleukin-2 production; GO:0045668|negative regulation of osteoblast differentiation; GO:0090050|positive regulation of cell migration involved in sprouting angiogenesis; GO:1901223|negative regulation of NIK/NF-kappaB signaling"	GO:0000118|histone deacetylase complex; GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005829|cytosol	GO:0003682|chromatin binding; GO:0003714|transcription corepressor activity; GO:0005080|protein kinase C binding; GO:0019789|SUMO transferase activity; GO:0019901|protein kinase binding; GO:0032041|NAD-dependent histone deacetylase activity (H3-K14 specific); GO:0033613|activating transcription factor binding; GO:0046872|metal ion binding; GO:0070491|repressing transcription factor binding; GO:0071889|14-3-3 protein binding	ko:K11408|HDAC7	ko05034|Alcoholism; ko05203|Viral carcinogenesis	5113	XP_015155723.1	XP_015155723.1 histone deacetylase 7 isoform X3 [Gallus gallus]	sp|Q8WUI4|HDAC7_HUMAN	sp|Q8WUI4|HDAC7_HUMAN Histone deacetylase 7 OS=Homo sapiens GN=HDAC7 PE=1 SV=2	9031.ENSGALP00000010190	histone deacetylase 7	COG0123	KOG1343	_	PF00850.16|Hist_deacetyl|Histone deacetylase domain|ENSGALT00000097050|m.15223:839-1157
ENSGALG00000039738	0.109896801	0.352521089	-1.596271759	0.015283539	0.026010001	down	yes	0.190220538	0.139469864	0	0.373655801	0.392875755	0.291031709	2	55720265	55781809	+	SLC9A3	protein_coding	GO:0006885|regulation of pH; GO:0098719|sodium ion import across plasma membrane	GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0016324|apical plasma membrane; GO:0031526|brush border membrane	GO:0015385|sodium:proton antiporter activity; GO:0030165|PDZ domain binding	"ko:K12040|SLC9A3,NHE3"	ko04964|Proximal tubule bicarbonate reclamation; ko04974|Protein digestion and absorption; ko04976|Bile secretion; ko04978|Mineral absorption	2493	XP_004935132.1	XP_004935132.1 sodium/hydrogen exchanger 3 isoform X1 [Gallus gallus]	sp|Q28362|SL9A3_DIDVI	sp|Q28362|SL9A3_DIDVI Sodium/hydrogen exchanger 3 OS=Didelphis virginiana GN=SLC9A3 PE=1 SV=1	_	_	_	_	_	PF00999.18|Na_H_Exchanger|Sodium/hydrogen exchanger family|ENSGALT00000048319|m.787:53-457
ENSGALG00000039741	2.927229731	10.44359029	-1.831470509	1.46E-31	2.52E-30	down	yes	2.308049843	3.343253564	3.130385787	10.48154975	9.473345253	11.37587588	21	5470172	5483241	-	TNFRSF8	protein_coding	GO:0006954|inflammatory response; GO:0006955|immune response; GO:0007411|axon guidance; GO:0010977|negative regulation of neuron projection development; GO:0032496|response to lipopolysaccharide; GO:0042127|regulation of cell population proliferation; GO:0042535|positive regulation of tumor necrosis factor biosynthetic process; GO:0042981|regulation of apoptotic process; GO:0043065|positive regulation of apoptotic process; GO:0045556|positive regulation of TRAIL biosynthetic process; GO:0071260|cellular response to mechanical stimulus; GO:0097190|apoptotic signaling pathway	GO:0005634|nucleus; GO:0005887|integral component of plasma membrane; GO:0043005|neuron projection; GO:0070062|extracellular exosome	GO:0005031|tumor necrosis factor-activated receptor activity; GO:0048406|nerve growth factor binding	"ko:K05145|TNFRSF8,CD30"	ko04060|Cytokine-cytokine receptor interaction	1872	XP_015152299.2	XP_015152299.2 tumor necrosis factor receptor superfamily member 8 isoform X1 [Gallus gallus]	sp|Q60846|TNR8_MOUSE	sp|Q60846|TNR8_MOUSE Tumor necrosis factor receptor superfamily member 8 OS=Mus musculus GN=Tnfrsf8 PE=2 SV=1	_	_	_	_	_	PF00020.15|TNFR_c6|TNFR/NGFR cysteine-rich region|ENSGALT00000067560|m.4266:159-199
ENSGALG00000039772	0.290246412	0.798698261	-1.429454503	5.71E-05	0.000144953	down	yes	0.255239911	0.42106978	0.194429545	0.774064742	0.826499075	0.795530965	3	35972263	36229904	+	RGS7	protein_coding	GO:0007186|G protein-coupled receptor signaling pathway; GO:0008277|regulation of G protein-coupled receptor signaling pathway; GO:0009968|negative regulation of signal transduction; GO:0035556|intracellular signal transduction; GO:0043547|positive regulation of GTPase activity	GO:0005634|nucleus; GO:0005829|cytosol; GO:0005834|heterotrimeric G-protein complex; GO:0005886|plasma membrane; GO:0032991|protein-containing complex; GO:0044292|dendrite terminus	GO:0005096|GTPase activator activity; GO:0031681|G-protein beta-subunit binding	ko:K16449|RGS	--	2324	XP_015139429.2	XP_015139429.2 regulator of G-protein signaling 7 isoform X5 [Gallus gallus]	sp|P49803|RGS7_RAT	sp|P49803|RGS7_RAT Regulator of G-protein signaling 7 OS=Rattus norvegicus GN=Rgs7 PE=1 SV=2	_	_	_	_	_	"PF00615.16|RGS|Regulator of G protein signaling domain|ENSGALT00000099798|m.11624:335-447;PF00610.18|DEP|Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)|ENSGALT00000099798|m.11624:40-110;PF00631.19|G-gamma|GGL domain|ENSGALT00000099798|m.11624:255-315"
ENSGALG00000039837	1.077528499	0.522491204	1.030223607	0.021464491	0.035479541	up	yes	1.272370049	0.905464507	1.05475094	0.633440765	0.251608852	0.682423996	1	197392646	197395026	+	CCKBR	protein_coding	--	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0004930|G protein-coupled receptor activity	ko:K04195|CCKBR	ko04020|Calcium signaling pathway; ko04080|Neuroactive ligand-receptor interaction; ko04971|Gastric acid secretion	1408	NP_001001742.1	NP_001001742.1 gastrin/cholecystokinin type B receptor [Gallus gallus]	sp|P70031|CCKAR_XENLA	sp|P70031|CCKAR_XENLA Cholecystokinin receptor OS=Xenopus laevis GN=cckar PE=2 SV=1	9031.ENSGALP00000027969	cholecystokinin receptor 	_	KOG3656	_	PF00001.18|7tm_1|7 transmembrane receptor (rhodopsin family)|ENSGALT00000074982|m.5015:89-400;PF10320.6|7TM_GPCR_Srsx|Serpentine type 7TM GPCR chemoreceptor Srsx|ENSGALT00000074982|m.5015:83-214;PF13853.3|7tm_4|Olfactory receptor|ENSGALT00000074982|m.5015:80-210
ENSGALG00000039869	7.721496054	2.759201845	1.48127739	0.001012829	0.00213243	up	yes	4.746944964	3.712495115	14.70504808	3.094961563	3.003839013	2.178804957	4	35039467	35039990	-	PYURF	protein_coding	GO:0006506|GPI anchor biosynthetic process; GO:0009893|positive regulation of metabolic process	GO:0000506|glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex; GO:0005739|mitochondrion; GO:0005789|endoplasmic reticulum membrane; GO:0005886|plasma membrane	--	--	--	333	POI19571.1	"POI19571.1 hypothetical protein CIB84_016684, partial [Bambusicola thoracicus]"	sp|Q9D1C3|PREY_MOUSE	"sp|Q9D1C3|PREY_MOUSE Protein preY, mitochondrial OS=Mus musculus GN=Pyurf PE=1 SV=1"	9031.ENSGALP00000037578	annotation not avaliable	_	_	NOG77141	PF03966.13|Trm112p|Trm112p-like protein|ENSGALT00000051420|m.239:48-86
ENSGALG00000039878	3.986647149	16.5653902	-2.05218072	4.28E-66	2.50E-64	down	yes	4.544904462	3.135665924	4.279371062	15.20665479	16.93768911	17.5518267	26	4925640	4939940	-	TFEB	protein_coding	"GO:0001892|embryonic placenta development; GO:0002250|adaptive immune response; GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated; GO:0006914|autophagy; GO:0006959|humoral immune response; GO:0007040|lysosome organization; GO:0010508|positive regulation of autophagy; GO:0045944|positive regulation of transcription by RNA polymerase II"	GO:0005634|nucleus; GO:0005737|cytoplasm	GO:0003700|DNA-binding transcription factor activity; GO:0044212|transcription regulatory region DNA binding; GO:0046983|protein dimerization activity	ko:K15590|TFEB	ko04137|Mitophagy - animal	3251	XP_015154434.1	XP_015154434.1 transcription factor EB isoform X1 [Gallus gallus]	sp|P19484|TFEB_HUMAN	sp|P19484|TFEB_HUMAN Transcription factor EB OS=Homo sapiens GN=TFEB PE=1 SV=3	9031.ENSGALP00000005375	transcription factor EB 	_	KOG1318	_	PF15951.2|MITF_TFEB_C_3_N|MITF/TFEB/TFEC/TFE3 N-terminus|ENSGALT00000075702|m.8271:70-222;PF11851.5|DUF3371|Domain of unknown function (DUF3371)|ENSGALT00000075702|m.8271:381-517;PF00010.23|HLH|Helix-loop-helix DNA-binding domain|ENSGALT00000075702|m.8271:296-349
ENSGALG00000039887	1.136088462	0.496162593	1.179045608	0.011805397	0.020586609	up	yes	0.955537885	1.100944755	1.351782747	0.325193002	0.773819279	0.389475498	25	3862075	3863720	+	ENSGALG00000039887	protein_coding	GO:0006953|acute-phase response	GO:0005576|extracellular region	GO:0030246|carbohydrate binding; GO:0046872|metal ion binding	--	--	1158	NP_001300649.1	"NP_001300649.1 C-reactive protein, pentraxin-related precursor [Gallus gallus]"	sp|P07629|SAMP_MESAU	sp|P07629|SAMP_MESAU Serum amyloid P-component OS=Mesocricetus auratus GN=APCS PE=1 SV=2	9031.ENSGALP00000034910	"C-reactive protein, pentraxin-related"	_	_	NOG44770	PF00354.14|Pentaxin|Pentaxin family|ENSGALT00000065594|m.7350:117-308;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000065594|m.7350:31-101;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000065594|m.7350:43-97;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000065594|m.7350:43-106
ENSGALG00000039935	0.464692377	3.192827091	-2.754281127	1.45E-25	1.86E-24	down	yes	0.282742525	0.695959432	0.415375175	3.152609408	3.05118776	3.374684106	2	48126705	48416766	+	PDE1C	protein_coding	GO:0006198|cAMP catabolic process; GO:0007165|signal transduction; GO:0007608|sensory perception of smell; GO:0046069|cGMP catabolic process; GO:0046676|negative regulation of insulin secretion; GO:0051592|response to calcium ion	GO:0005929|cilium; GO:0043025|neuronal cell body	"GO:0004115|3',5'-cyclic-AMP phosphodiesterase activity; GO:0004117|calmodulin-dependent cyclic-nucleotide phosphodiesterase activity; GO:0005516|calmodulin binding; GO:0030552|cAMP binding; GO:0046872|metal ion binding; GO:0048101|calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity"	ko:K13755|PDE1	ko00230|Purine metabolism; ko04020|Calcium signaling pathway; ko04740|Olfactory transduction; ko04742|Taste transduction; ko04924|Renin secretion; ko05032|Morphine addiction	2304	XP_025003321.1	"XP_025003321.1 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform X5 [Gallus gallus]"	sp|Q63421|PDE1C_RAT	"sp|Q63421|PDE1C_RAT Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C OS=Rattus norvegicus GN=Pde1c PE=1 SV=1"	9544.ENSMMUP00000002179	"phosphodiesterase 1C, calmodulin-dependent 70kDa"	_	KOG3688	_	PF00233.16|PDEase_I|3'5'-cyclic nucleotide phosphodiesterase|ENSGALT00000093214|m.672:287-514;PF08499.9|PDEase_I_N|3'5'-cyclic nucleotide phosphodiesterase N-terminal|ENSGALT00000093214|m.672:142-202
ENSGALG00000039958	9.535554265	3.858752621	1.302960489	1.24E-18	1.07E-17	up	yes	7.946093964	10.70943412	9.951134714	4.372125565	3.854578558	3.349553741	1	177480164	177499171	-	ENSGALG00000039958	protein_coding	--	--	--	--	--	2049	XP_417121.1	XP_417121.1 protein POLR1D isoform X1 [Gallus gallus]	sp|P0DPB5|RPC22_HUMAN	"sp|P0DPB5|RPC22_HUMAN Protein POLR1D, isoform 2 OS=Homo sapiens GN=POLR1D PE=1 SV=1"	9031.ENSGALP00000027563	RNA polymerase 1-3	_	_	NOG70655	_
ENSGALG00000039989	0.499360291	0.206768546	1.232531062	0.023749694	0.038821368	up	yes	0.673727298	0.24698872	0.577364854	0.242862082	0.199842513	0.177601043	9	20022139	20024015	-	GPR160	protein_coding	--	GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0043235|receptor complex	GO:0004930|G protein-coupled receptor activity	ko:K08438|GPR160	--	1877	XP_015147151.1	XP_015147151.1 probable G-protein coupled receptor 160 isoform X1 [Gallus gallus]	sp|Q9UJ42|GP160_HUMAN	sp|Q9UJ42|GP160_HUMAN Probable G-protein coupled receptor 160 OS=Homo sapiens GN=GPR160 PE=2 SV=1	9031.ENSGALP00000015255	G protein-coupled receptor 160	_	_	NOG44522	_
ENSGALG00000040026	0.295915445	1.060370164	-1.806904955	9.52E-05	0.000234382	down	yes	0.193859783	0.383773036	0.310113515	0.46668804	1.863101309	0.851321142	5	53031545	53041637	-	ENSGALG00000040026	protein_coding	--	--	--	ko:K17575|PPP1R36	--	2718	XP_001235694.3	XP_001235694.3 protein phosphatase 1 regulatory subunit 36 isoform X2 [Gallus gallus]	_	_	9031.ENSGALP00000036625	chromosome 14 open reading frame 50	_	_	NOG18076	PF14895.3|PPPI_inhib|Protein phosphatase 1 inhibitor|ENSGALT00000061754|m.3982:40-234
ENSGALG00000040031	5.623000278	2.103286605	1.414415103	5.14E-15	3.44E-14	up	yes	5.906972052	6.274182022	4.68784676	2.534483082	2.078583614	1.696793119	9	892848	898559	+	SLC35G2	protein_coding	--	GO:0016021|integral component of membrane	--	--	--	2346	XP_019474555.1	XP_019474555.1 PREDICTED: LOW QUALITY PROTEIN: solute carrier family 35 member G2 [Meleagris gallopavo]	sp|Q5ZJZ4|S35G2_CHICK	sp|Q5ZJZ4|S35G2_CHICK Solute carrier family 35 member G2 OS=Gallus gallus GN=SLC35G2 PE=2 SV=1	9031.ENSGALP00000001962	Transmembrane protein 22 	_	_	NOG48006	PF00892.17|EamA|EamA-like transporter family|ENSGALT00000051737|m.8252:217-350;PF00892.17|EamA|EamA-like transporter family|ENSGALT00000051737|m.8252:369-501
ENSGALG00000040079	7.914683066	21.83172508	-1.462661663	5.16E-68	3.18E-66	down	yes	7.377343845	7.728798425	8.637906928	22.17755189	22.18981771	21.12780565	2	130175913	130483288	+	ZFPM2	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0001570|vasculogenesis; GO:0001701|in utero embryonic development; GO:0003148|outflow tract septum morphogenesis; GO:0003151|outflow tract morphogenesis; GO:0003181|atrioventricular valve morphogenesis; GO:0003192|mitral valve formation; GO:0003195|tricuspid valve formation; GO:0003221|right ventricular cardiac muscle tissue morphogenesis; GO:0006351|transcription, DNA-templated; GO:0007507|heart development; GO:0030324|lung development; GO:0045599|negative regulation of fat cell differentiation; GO:0045892|negative regulation of transcription, DNA-templated; GO:0045893|positive regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0048568|embryonic organ development; GO:0048738|cardiac muscle tissue development; GO:0055008|cardiac muscle tissue morphogenesis; GO:0060045|positive regulation of cardiac muscle cell proliferation; GO:0060412|ventricular septum morphogenesis; GO:0060548|negative regulation of cell death; GO:0060979|vasculogenesis involved in coronary vascular morphogenesis; GO:2000020|positive regulation of male gonad development; GO:2000195|negative regulation of female gonad development"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm	"GO:0001085|RNA polymerase II transcription factor binding; GO:0001227|DNA-binding transcription repressor activity, RNA polymerase II-specific; GO:0003677|DNA binding; GO:0003714|transcription corepressor activity; GO:0008134|transcription factor binding; GO:0046872|metal ion binding"	"ko:K17442|ZFPM2,FOG2"	ko05206|MicroRNAs in cancer	3505	XP_418380.4	XP_418380.4 zinc finger protein ZFPM2 isoform X1 [Gallus gallus]	sp|Q8CCH7|FOG2_MOUSE	sp|Q8CCH7|FOG2_MOUSE Zinc finger protein ZFPM2 OS=Mus musculus GN=Zfpm2 PE=1 SV=2	59729.ENSTGUP00000012555	Zinc finger protein ZFPM2 (Zinc finger protein multitype 2)(Friend of GATA protein 2)(FOG-2) [...] 	_	KOG1721	_	PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000095082|m.2272:624-643;PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000095082|m.2272:1056-1074
ENSGALG00000040120	2.402019979	0.943608378	1.338773041	0.000112518	0.000273829	up	yes	3.247069917	2.27253837	1.68645165	1.036321971	0.933966752	0.860536412	5	178109	184568	-	ENSGALG00000040120	protein_coding	--	GO:0005739|mitochondrion	GO:0047961|glycine N-acyltransferase activity	--	--	989	XP_025007096.1	XP_025007096.1 glycine N-acyltransferase-like protein 3 isoform X3 [Gallus gallus]	sp|Q5SZD4|GLYL3_HUMAN	sp|Q5SZD4|GLYL3_HUMAN Glycine N-acyltransferase-like protein 3 OS=Homo sapiens GN=GLYATL3 PE=2 SV=3	_	_	_	_	_	"PF06021.8|Gly_acyl_tr_N|Aralkyl acyl-CoA:amino acid N-acyltransferase|ENSGALT00000060579|m.2010:1-185;PF08444.7|Gly_acyl_tr_C|Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region|ENSGALT00000060579|m.2010:188-265"
ENSGALG00000040161	7.802291131	3.702194664	1.073473347	2.39E-15	1.63E-14	up	yes	7.819184736	7.850510067	7.737178588	3.192428086	4.390048558	3.524107347	2	51141125	51145397	-	C7orf25	protein_coding	--	--	--	--	--	1938	XP_004939643.1	XP_004939643.1 UPF0415 protein C7orf25 homolog isoform X1 [Gallus gallus]	sp|Q1LZE8|CG025_BOVIN	sp|Q1LZE8|CG025_BOVIN UPF0415 protein C7orf25 homolog OS=Bos taurus PE=2 SV=1	9031.ENSGALP00000020125	chromosome 7 open reading frame 25	_	KOG4529	_	PF07000.8|DUF1308|Protein of unknown function (DUF1308)|ENSGALT00000104337|m.724:59-422
ENSGALG00000040180	13.15595615	35.83498579	-1.444959022	3.83E-28	5.50E-27	down	yes	14.37556666	13.30272461	11.78957718	30.87418626	41.40316224	35.22760887	2	107911432	107912427	-	CEBPD	protein_coding	"GO:0002244|hematopoietic progenitor cell differentiation; GO:0006357|regulation of transcription by RNA polymerase II; GO:0045444|fat cell differentiation; GO:0045669|positive regulation of osteoblast differentiation; GO:0045892|negative regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0048839|inner ear development"	GO:0005634|nucleus; GO:0005654|nucleoplasm	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003677|DNA binding; GO:0042803|protein homodimerization activity; GO:0044212|transcription regulatory region DNA binding; GO:0046982|protein heterodimerization activity"	ko:K10050|CEBPD	--	909	XP_015138136.1	XP_015138136.1 CCAAT/enhancer-binding protein delta [Gallus gallus]	sp|Q00322|CEBPD_MOUSE	sp|Q00322|CEBPD_MOUSE CCAAT/enhancer-binding protein delta OS=Mus musculus GN=Cebpd PE=1 SV=2	59729.ENSTGUP00000011171	CCAAT/enhancer-binding protein delta (C/EBP delta)(Nuclear factor NF-IL6-beta)(NF-IL6-beta)  [...] 	_	KOG3119	_	PF07716.12|bZIP_2|Basic region leucine zipper|ENSGALT00000066024|m.1741:223-274
ENSGALG00000040184	11.02031004	5.384451247	1.031925229	5.40E-25	6.74E-24	up	yes	11.12621728	10.45534693	11.47936591	5.224761085	5.667575806	5.261016848	1	75676381	75723185	+	RIMKLB	protein_coding	GO:0006464|cellular protein modification process; GO:0008652|cellular amino acid biosynthetic process	GO:0005737|cytoplasm; GO:0005829|cytosol	GO:0005524|ATP binding; GO:0046872|metal ion binding; GO:0072590|N-acetyl-L-aspartate-L-glutamate ligase activity; GO:0072591|citrate-L-glutamate ligase activity	"ko:K18310|RIMKLB,NAAGS-I"	"ko00250|Alanine, aspartate and glutamate metabolism; ko01100|Metabolic pathways"	2474	EOB06558.1	"EOB06558.1 Ribosomal protein S6 modification-like protein B, partial [Anas platyrhynchos]"	sp|Q9ULI2|RIMKB_HUMAN	sp|Q9ULI2|RIMKB_HUMAN Beta-citrylglutamate synthase B OS=Homo sapiens GN=RIMKLB PE=2 SV=2	9031.ENSGALP00000023045	ribosomal modification protein rimK-like family member B	COG0189	_	_	"PF08443.8|RimK|RimK-like ATP-grasp domain|ENSGALT00000096028|m.2272:114-302;PF02955.13|GSH-S_ATP|Prokaryotic glutathione synthetase, ATP-grasp domain|ENSGALT00000096028|m.2272:155-266;PF02655.11|ATP-grasp_3|ATP-grasp domain|ENSGALT00000096028|m.2272:112-280"
ENSGALG00000040189	0.572583789	1.391010021	-1.265929811	0.00046226	0.001025612	down	yes	1.043590503	0.300063319	0.374097547	1.577875662	1.26248729	1.33266711	1	110342171	110362181	-	RIPK4	protein_coding	GO:0002009|morphogenesis of an epithelium; GO:0051092|positive regulation of NF-kappaB transcription factor activity	GO:0005737|cytoplasm; GO:0016020|membrane	GO:0004674|protein serine/threonine kinase activity; GO:0005524|ATP binding	ko:K08848|RIPK4	--	2575	XP_004934622.2	XP_004934622.2 receptor-interacting serine/threonine-protein kinase 4 [Gallus gallus]	sp|Q9ERK0|RIPK4_MOUSE	sp|Q9ERK0|RIPK4_MOUSE Receptor-interacting serine/threonine-protein kinase 4 OS=Mus musculus GN=Ripk4 PE=1 SV=2	9031.ENSGALP00000025962	receptor-interacting serine-threonine kinase 4	COG0515;COG0666	KOG0192;KOG0504	_	PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000070155|m.3151:478-566;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000070155|m.3151:568-631;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000070155|m.3151:635-697;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000070155|m.3151:673-762;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000070155|m.3151:768-824;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000070155|m.3151:504-555;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000070155|m.3151:551-581;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000070155|m.3151:603-654;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000070155|m.3151:638-689;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000070155|m.3151:670-722;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000070155|m.3151:704-754;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000070155|m.3151:768-820;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000070155|m.3151:506-534;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000070155|m.3151:536-566;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000070155|m.3151:602-631;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000070155|m.3151:638-666;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000070155|m.3151:668-699;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000070155|m.3151:704-732;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000070155|m.3151:735-764;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000070155|m.3151:769-797;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000070155|m.3151:800-824;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000070155|m.3151:502-543;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000070155|m.3151:527-576;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000070155|m.3151:637-675;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000070155|m.3151:653-699;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000070155|m.3151:694-742;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000070155|m.3151:92-346;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000070155|m.3151:601-630;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000070155|m.3151:668-696;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000070155|m.3151:768-795;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000070155|m.3151:92-347
ENSGALG00000040212	11.09190197	22.23149053	-1.002446615	8.06E-44	2.36E-42	down	yes	11.27222304	11.07266424	10.93081863	21.29873664	22.01564489	23.38009006	2	42699453	42723188	+	FYCO1	protein_coding	GO:0006458|'de novo' protein folding; GO:0061077|chaperone-mediated protein folding; GO:0072383|plus-end-directed vesicle transport along microtubule; GO:1901098|positive regulation of autophagosome maturation	GO:0005764|lysosome; GO:0005770|late endosome; GO:0005776|autophagosome; GO:0005794|Golgi apparatus; GO:0016020|membrane; GO:0016021|integral component of membrane; GO:0043231|intracellular membrane-bounded organelle	GO:0005524|ATP binding; GO:0044183|protein folding chaperone; GO:0046872|metal ion binding; GO:0051082|unfolded protein binding	--	--	4623	NP_001039304.2	NP_001039304.2 FYVE and coiled-coil domain-containing protein 1 [Gallus gallus]	sp|Q9BQS8|FYCO1_HUMAN	sp|Q9BQS8|FYCO1_HUMAN FYVE and coiled-coil domain-containing protein 1 OS=Homo sapiens GN=FYCO1 PE=1 SV=3	9031.ENSGALP00000019146	FYVE and coiled-coil domain containing 1 	_	KOG1729	_	PF01363.18|FYVE|FYVE zinc finger|ENSGALT00000061252|m.519:1238-1298;PF02759.16|RUN|RUN domain|ENSGALT00000061252|m.519:61-165
ENSGALG00000040241	0.166812082	0.812018488	-2.216953982	6.02E-08	2.19E-07	down	yes	0.169722395	0.260193998	0.070519852	0.824126323	0.945846454	0.666082687	10	13669102	13847266	+	NTRK3	protein_coding	GO:0007169|transmembrane receptor protein tyrosine kinase signaling pathway; GO:0007399|nervous system development; GO:0007507|heart development; GO:0030154|cell differentiation	GO:0005887|integral component of plasma membrane	GO:0004714|transmembrane receptor protein tyrosine kinase activity; GO:0005030|neurotrophin receptor activity; GO:0005524|ATP binding	"ko:K05101|NTRK3,TRKC"	ko04722|Neurotrophin signaling pathway; ko05230|Central carbon metabolism in cancer	3149	NP_990500.1	NP_990500.1 NT-3 growth factor receptor precursor [Gallus gallus]	sp|Q91044|NTRK3_CHICK	sp|Q91044|NTRK3_CHICK NT-3 growth factor receptor OS=Gallus gallus GN=NTRK3 PE=1 SV=2	13616.ENSMODP00000035165	"neurotrophic tyrosine kinase, receptor, type 3"	COG0515	KOG1026	_	PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000072944|m.5678:541-726;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000072944|m.5678:738-836;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000072944|m.5678:542-834;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000072944|m.5678:210-301;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000072944|m.5678:323-391;PF16920.2|TPKR_C2|Tyrosine-protein kinase receptor C2 Ig-like domain|ENSGALT00000072944|m.5678:163-208;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000072944|m.5678:210-288;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000072944|m.5678:216-297;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000072944|m.5678:104-161;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000072944|m.5678:210-301
ENSGALG00000040260	273.6541506	67.73782366	2.01415995	1.69E-183	1.20E-180	up	yes	287.3897029	266.8961504	266.6765985	71.29701951	61.42952607	70.4869254	33	7109678	7113350	-	TUBA1C	protein_coding	GO:0007017|microtubule-based process	GO:0005737|cytoplasm; GO:0005874|microtubule	GO:0003924|GTPase activity; GO:0005200|structural constituent of cytoskeleton; GO:0005525|GTP binding	ko:K07374|TUBA	ko04145|Phagosome; ko04210|Apoptosis; ko04530|Tight junction; ko04540|Gap junction; ko05130|Pathogenic Escherichia coli infection	1475	XP_015155800.2	XP_015155800.2 tubulin alpha-1C chain [Gallus gallus]	sp|P68365|TBA1C_CRIGR	sp|P68365|TBA1C_CRIGR Tubulin alpha-1C chain OS=Cricetulus griseus GN=TUBA1C PE=2 SV=1	_	_	_	_	_	"PF00091.22|Tubulin|Tubulin/FtsZ family, GTPase domain|ENSGALT00000058579|m.15636:3-213;PF03953.14|Tubulin_C|Tubulin C-terminal domain|ENSGALT00000058579|m.15636:263-391"
ENSGALG00000040272	25.35646896	12.29020618	1.04424021	1.15E-32	2.09E-31	up	yes	23.69137803	26.34340013	26.03462873	11.88195856	12.98955397	11.99910601	1	15818747	15825318	-	ALG10	protein_coding	GO:0006488|dolichol-linked oligosaccharide biosynthetic process; GO:0007605|sensory perception of sound; GO:0060117|auditory receptor cell development	GO:0005789|endoplasmic reticulum membrane; GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0004583|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity; GO:0015459|potassium channel regulator activity	ko:K03850|ALG10	ko00510|N-Glycan biosynthesis; ko01100|Metabolic pathways	2015	NP_001026565.1	"NP_001026565.1 dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase [Gallus gallus]"	sp|O88788|AG10B_RAT	"sp|O88788|AG10B_RAT Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase OS=Rattus norvegicus GN=Alg10b PE=1 SV=1"	9031.ENSGALP00000021221	asparagine-linked glycosylation 10 homolog B 	_	KOG2642	_	PF04922.9|DIE2_ALG10|DIE2/ALG10 family|ENSGALT00000070013|m.532:52-446
ENSGALG00000040320	4.789116342	0.774976809	2.61204685	1.11E-15	7.82E-15	up	yes	4.082602546	5.425479015	4.859267466	0.527884346	1.084845915	0.712200168	27	6203738	6205370	+	HOXB8	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006351|transcription, DNA-templated; GO:0007625|grooming behavior; GO:0008344|adult locomotory behavior; GO:0009952|anterior/posterior pattern specification; GO:0019233|sensory perception of pain; GO:0021516|dorsal spinal cord development; GO:0045638|negative regulation of myeloid cell differentiation; GO:0048704|embryonic skeletal system morphogenesis"	GO:0005654|nucleoplasm	GO:0003700|DNA-binding transcription factor activity; GO:0043565|sequence-specific DNA binding	ko:K09308|HOX_8	--	826	NP_990242.1	NP_990242.1 homeobox protein Hox-B8 [Gallus gallus]	sp|P17481|HXB8_HUMAN	sp|P17481|HXB8_HUMAN Homeobox protein Hox-B8 OS=Homo sapiens GN=HOXB8 PE=2 SV=2	9031.ENSGALP00000027984	Homeobox protein Hox-B8 Fragment (Chox-2.4); Sequence-specific transcription factor which is [...] 	_	KOG0489	_	PF00046.26|Homeobox|Homeobox domain|ENSGALT00000075818|m.9040:145-201
ENSGALG00000040360	6.340516243	35.60489963	-2.487535144	5.69E-143	2.02E-140	down	yes	6.260049478	6.709860228	6.051639021	36.05973951	37.29283339	33.462126	13	9770031	9772644	-	DUSP1	protein_coding	GO:0000188|inactivation of MAPK activity; GO:0001706|endoderm formation; GO:0006979|response to oxidative stress; GO:0009416|response to light stimulus; GO:0032355|response to estradiol; GO:0032526|response to retinoic acid; GO:0032870|cellular response to hormone stimulus; GO:0033574|response to testosterone; GO:0035335|peptidyl-tyrosine dephosphorylation; GO:0035556|intracellular signal transduction; GO:0035970|peptidyl-threonine dephosphorylation; GO:0042542|response to hydrogen peroxide; GO:0042981|regulation of apoptotic process; GO:0043065|positive regulation of apoptotic process; GO:0043066|negative regulation of apoptotic process; GO:0043407|negative regulation of MAP kinase activity; GO:0043409|negative regulation of MAPK cascade; GO:0051384|response to glucocorticoid; GO:0051447|negative regulation of meiotic cell cycle; GO:0051591|response to cAMP; GO:0051592|response to calcium ion; GO:0070373|negative regulation of ERK1 and ERK2 cascade; GO:0071850|mitotic cell cycle arrest; GO:0090266|regulation of mitotic cell cycle spindle assembly checkpoint; GO:2000279|negative regulation of DNA biosynthetic process	GO:0005634|nucleus; GO:0005737|cytoplasm	GO:0004726|non-membrane spanning protein tyrosine phosphatase activity; GO:0008138|protein tyrosine/serine/threonine phosphatase activity; GO:0008330|protein tyrosine/threonine phosphatase activity; GO:0017017|MAP kinase tyrosine/serine/threonine phosphatase activity; GO:0019838|growth factor binding	ko:K21278|DUSP1	ko04010|MAPK signaling pathway; ko04726|Serotonergic synapse; ko05418|Fluid shear stress and atherosclerosis	1877	NP_001078828.1	NP_001078828.1 dual specificity protein phosphatase 1 [Gallus gallus]	sp|P28562|DUS1_HUMAN	sp|P28562|DUS1_HUMAN Dual specificity protein phosphatase 1 OS=Homo sapiens GN=DUSP1 PE=1 SV=3	9031.ENSGALP00000005877	MAP kinase phosphatase-1 Fragment 	COG2453	KOG1716	_	"PF00782.17|DSPc|Dual specificity phosphatase, catalytic domain|ENSGALT00000082972|m.8603:216-345;PF00581.17|Rhodanese|Rhodanese-like domain|ENSGALT00000082972|m.8603:53-164;PF00102.24|Y_phosphatase|Protein-tyrosine phosphatase|ENSGALT00000082972|m.8603:251-309"
ENSGALG00000040369	133.2276159	598.3409427	-2.166990452	3.38E-183	2.27E-180	down	yes	149.6169468	129.146039	120.919862	582.2337524	630.6076187	582.1814571	1	4138801	4175957	+	PFKFB3	protein_coding	"GO:0006000|fructose metabolic process; GO:0006003|fructose 2,6-bisphosphate metabolic process"	--	"GO:0003873|6-phosphofructo-2-kinase activity; GO:0004331|fructose-2,6-bisphosphate 2-phosphatase activity; GO:0005524|ATP binding"	ko:K01103|PFKFB3	ko00051|Fructose and mannose metabolism; ko04066|HIF-1 signaling pathway; ko04152|AMPK signaling pathway	2216	XP_008636616.2	"XP_008636616.2 PREDICTED: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X4 [Corvus brachyrhynchos]"	sp|Q5R9C1|F263_PONAB	"sp|Q5R9C1|F263_PONAB 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 OS=Pongo abelii GN=PFKFB3 PE=2 SV=2"	59729.ENSTGUP00000002094	"6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (6PF-2-K/Fru-2,6-P2ASE brain/placenta- [...] "	COG0406	KOG0234	_	PF01591.15|6PF2K|6-phosphofructo-2-kinase|ENSGALT00000049952|m.280:39-260;PF00300.19|His_Phos_1|Histidine phosphatase superfamily (branch 1)|ENSGALT00000049952|m.280:263-446;PF13671.3|AAA_33|AAA domain|ENSGALT00000049952|m.280:51-164
ENSGALG00000040371	27.01132432	10.51949981	1.359661478	1.87E-55	7.91E-54	up	yes	26.04366852	28.19012832	26.80017613	10.47757946	10.91883748	10.1620825	5	18622009	18627613	-	ENSGALG00000040371	protein_coding	--	--	--	ko:K04008|CD59	ko04610|Complement and coagulation cascades; ko04640|Hematopoietic cell lineage	1868	XP_003206417.1	XP_003206417.1 PREDICTED: CD59 glycoprotein [Meleagris gallopavo]	_	_	9031.ENSGALP00000040586	"CD59 molecule, complement regulatory protein"	_	_	NOG83475	_
ENSGALG00000040444	0.335849833	1.054997815	-1.622632807	1.92E-06	5.94E-06	down	yes	0.283285425	0.40057416	0.323689913	1.07318423	1.120383503	0.971425713	1	11192619	11310904	+	SEMA3C	protein_coding	GO:0007399|nervous system development; GO:0030154|cell differentiation; GO:0050919|negative chemotaxis	GO:0005615|extracellular space	GO:0038191|neuropilin binding	ko:K06840|SEMA3	ko04360|Axon guidance	2510	XP_015156278.1	XP_015156278.1 semaphorin-3C isoform X1 [Gallus gallus]	sp|O42236|SEM3C_CHICK	sp|O42236|SEM3C_CHICK Semaphorin-3C OS=Gallus gallus GN=SEMA3C PE=2 SV=1	59729.ENSTGUP00000002688	Semaphorin-3C Precursor (Semaphorin-E)(Sema E) [Taeniopygia guttata]	_	KOG3611	_	PF01403.16|Sema|Sema domain|ENSGALT00000101757|m.386:57-492;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000101757|m.386:587-661
ENSGALG00000040465	10.76907346	30.5351485	-1.502710081	5.19E-71	3.50E-69	down	yes	12.03698658	10.86020837	9.41002544	30.70725633	30.50386002	30.39432916	7	33308256	33416501	-	ZEB2	protein_coding	GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0001755|neural crest cell migration; GO:0001756|somitogenesis; GO:0001843|neural tube closure; GO:0007399|nervous system development; GO:0021540|corpus callosum morphogenesis; GO:0021766|hippocampus development; GO:0021846|cell proliferation in forebrain; GO:0021957|corticospinal tract morphogenesis; GO:0030177|positive regulation of Wnt signaling pathway; GO:0043507|positive regulation of JUN kinase activity; GO:0045636|positive regulation of melanocyte differentiation; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0048023|positive regulation of melanin biosynthetic process; GO:0048066|developmental pigmentation; GO:0048668|collateral sprouting; GO:0050772|positive regulation of axonogenesis; GO:0061373|mammillary axonal complex development; GO:0097324|melanocyte migration; GO:1902748|positive regulation of lens fiber cell differentiation; GO:1903056|regulation of melanosome organization	GO:0000790|nuclear chromatin; GO:0005634|nucleus; GO:0005730|nucleolus; GO:0005829|cytosol	"GO:0001227|DNA-binding transcription repressor activity, RNA polymerase II-specific; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0019208|phosphatase regulator activity; GO:0043565|sequence-specific DNA binding; GO:0046872|metal ion binding; GO:0070412|R-SMAD binding"	ko:K09299|ZEB1_2	ko05206|MicroRNAs in cancer	4215	NP_001305395.1	NP_001305395.1 zinc finger E-box-binding homeobox 2 [Gallus gallus]	sp|O60315|ZEB2_HUMAN	sp|O60315|ZEB2_HUMAN Zinc finger E-box-binding homeobox 2 OS=Homo sapiens GN=ZEB2 PE=1 SV=1	9031.ENSGALP00000020312	zinc finger E-box binding homeobox 2	COG5048	KOG3623	_	"PF05605.9|zf-Di19|Drought induced 19 protein (Di19), zinc-binding|ENSGALT00000100475|m.6726:211-262;PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000100475|m.6726:310-333"
ENSGALG00000040478	2.533171197	11.81352049	-2.216959179	3.97E-55	1.67E-53	down	yes	1.956352318	3.060051667	2.583109606	10.6316905	12.67443742	12.13443355	1	194700308	194747859	-	CAPN5	protein_coding	GO:0006508|proteolysis	GO:0005737|cytoplasm; GO:0005925|focal adhesion; GO:0009986|cell surface; GO:0070062|extracellular exosome	GO:0004198|calcium-dependent cysteine-type endopeptidase activity	ko:K08574|CAPN5	--	2828	XP_417278.2	XP_417278.2 calpain-5 [Gallus gallus]	sp|O08688|CAN5_MOUSE	sp|O08688|CAN5_MOUSE Calpain-5 OS=Mus musculus GN=Capn5 PE=1 SV=1	9031.ENSGALP00000001091	calpain 5	_	KOG0045	_	"PF00648.18|Peptidase_C2|Calpain family cysteine protease|ENSGALT00000047372|m.4823:27-339;PF01067.19|Calpain_III|Calpain large subunit, domain III|ENSGALT00000047372|m.4823:360-490;PF00168.27|C2|C2 domain|ENSGALT00000047372|m.4823:519-604"
ENSGALG00000040586	108.919035	42.90108938	1.343966123	1.21E-98	1.42E-96	up	yes	110.1523066	110.6072442	105.9975542	44.65620315	41.03286135	43.01420365	26	526440	534597	+	TUBA3E	protein_coding	GO:0007017|microtubule-based process; GO:0030705|cytoskeleton-dependent intracellular transport; GO:0051301|cell division	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005874|microtubule; GO:0015630|microtubule cytoskeleton; GO:0031982|vesicle	GO:0003924|GTPase activity; GO:0005198|structural molecule activity; GO:0005200|structural constituent of cytoskeleton; GO:0005525|GTP binding	ko:K07374|TUBA	ko04145|Phagosome; ko04210|Apoptosis; ko04530|Tight junction; ko04540|Gap junction; ko05130|Pathogenic Escherichia coli infection	1679	NP_001292069.1	NP_001292069.1 tubulin alpha-8 chain [Gallus gallus]	sp|Q9BQE3|TBA1C_HUMAN	sp|Q9BQE3|TBA1C_HUMAN Tubulin alpha-1C chain OS=Homo sapiens GN=TUBA1C PE=1 SV=1	9031.ENSGALP00000000588	Tubulin alpha-8 chain Fragment ; Tubulin is the major constituent of microtubules. It binds  [...] 	COG5023	KOG1376	_	"PF00091.22|Tubulin|Tubulin/FtsZ family, GTPase domain|ENSGALT00000046954|m.7542:3-213;PF03953.14|Tubulin_C|Tubulin C-terminal domain|ENSGALT00000046954|m.7542:263-391"
ENSGALG00000040619	1.826725298	0.615349941	1.55440023	2.05E-05	5.54E-05	up	yes	1.927722772	1.790316814	1.762136309	0.805677142	0.609925848	0.430446833	5	261217	263311	+	BAAT	protein_coding	GO:0006631|fatty acid metabolic process; GO:0006637|acyl-CoA metabolic process	GO:0005777|peroxisome	GO:0016410|N-acyltransferase activity; GO:0047617|acyl-CoA hydrolase activity	ko:K00659|BAAT	ko00120|Primary bile acid biosynthesis; ko00430|Taurine and hypotaurine metabolism; ko01040|Biosynthesis of unsaturated fatty acids; ko01100|Metabolic pathways; ko04146|Peroxisome; ko04976|Bile secretion	1230	XP_004941333.2	XP_004941333.2 LOW QUALITY PROTEIN: acyl-coenzyme A amino acid N-acyltransferase 2 [Gallus gallus]	sp|Q5FVR5|ACNT2_RAT	sp|Q5FVR5|ACNT2_RAT Acyl-coenzyme A amino acid N-acyltransferase 2 OS=Rattus norvegicus GN=Acnat2 PE=2 SV=1	_	_	_	_	_	PF08840.8|BAAT_C|BAAT / Acyl-CoA thioester hydrolase C terminal|ENSGALT00000064530|m.2060:206-402;PF04775.11|Bile_Hydr_Trans|Acyl-CoA thioester hydrolase/BAAT N-terminal region|ENSGALT00000064530|m.2060:14-143
ENSGALG00000040759	1.477527462	0.587032702	1.317034442	3.62E-09	1.49E-08	up	yes	1.747111439	1.143031542	1.542439404	0.454965786	0.549237483	0.756894836	4	91069174	91078804	-	CPXM1	protein_coding	--	GO:0005615|extracellular space	GO:0004180|carboxypeptidase activity; GO:0008237|metallopeptidase activity; GO:0008270|zinc ion binding	ko:K08638|CPXM1	--	4865	XP_015156815.1	XP_015156815.1 probable carboxypeptidase X1 [Gallus gallus]	sp|Q96SM3|CPXM1_HUMAN	sp|Q96SM3|CPXM1_HUMAN Probable carboxypeptidase X1 OS=Homo sapiens GN=CPXM1 PE=2 SV=2	28377.ENSACAP00000000285	"carboxypeptidase X (M14 family), member 1"	_	KOG2649	_	PF00246.21|Peptidase_M14|Zinc carboxypeptidase|ENSGALT00000095259|m.1883:377-683;PF00754.22|F5_F8_type_C|F5/8 type C domain|ENSGALT00000095259|m.1883:226-342;PF13620.3|CarboxypepD_reg|Carboxypeptidase regulatory-like domain|ENSGALT00000095259|m.1883:695-759;PF00583.22|Acetyltransf_1|Acetyltransferase (GNAT) family|ENSGALT00000095259|m.1884:191-270;PF13508.4|Acetyltransf_7|Acetyltransferase (GNAT) domain|ENSGALT00000095259|m.1884:185-270;PF13673.4|Acetyltransf_10|Acetyltransferase (GNAT) domain|ENSGALT00000095259|m.1884:179-272;PF13302.4|Acetyltransf_3|Acetyltransferase (GNAT) domain|ENSGALT00000095259|m.1884:180-270
ENSGALG00000040784	28.19537952	12.3379213	1.191702156	7.60E-48	2.58E-46	up	yes	28.26489021	28.23419796	28.08705039	11.399343	13.33608636	12.27833453	4	14195244	14202404	+	RAB39B	protein_coding	GO:0006914|autophagy; GO:0010506|regulation of autophagy; GO:0015031|protein transport; GO:0016192|vesicle-mediated transport; GO:0050808|synapse organization	GO:0005794|Golgi apparatus; GO:0005886|plasma membrane; GO:0030659|cytoplasmic vesicle membrane; GO:0043005|neuron projection	GO:0003924|GTPase activity; GO:0005525|GTP binding; GO:0031489|myosin V binding	ko:K07925|RAB39B	--	1884	XP_025891751.1	XP_025891751.1 ras-related protein Rab-39B isoform X2 [Nothoprocta perdicaria]	sp|Q17QU4|RB39B_BOVIN	sp|Q17QU4|RB39B_BOVIN Ras-related protein Rab-39B OS=Bos taurus GN=RAB39B PE=2 SV=1	_	_	_	_	_	"PF00071.19|Ras|Ras family|ENSGALT00000091854|m.16562:10-145;PF08477.10|Roc|Ras of Complex, Roc, domain of DAPkinase|ENSGALT00000091854|m.16562:10-126;PF00025.18|Arf|ADP-ribosylation factor family|ENSGALT00000091854|m.16562:8-133;PF01926.20|MMR_HSR1|50S ribosome-binding GTPase|ENSGALT00000091854|m.16562:11-114;PF04670.9|Gtr1_RagA|Gtr1/RagA G protein conserved region|ENSGALT00000091854|m.16562:11-133"
ENSGALG00000040833	16.41623963	35.94414624	-1.130155903	7.88E-64	4.35E-62	down	yes	16.26105555	15.82886101	17.15880231	36.28098452	35.43231501	36.11913918	7	17331574	17339738	-	ENSGALG00000040833	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated; GO:0006915|apoptotic process; GO:0042127|regulation of cell population proliferation"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005829|cytosol	--	--	--	3600	XP_025008340.1	XP_025008340.1 LOW QUALITY PROTEIN: cell division cycle-associated protein 7 [Gallus gallus]	sp|Q9BWT1|CDCA7_HUMAN	sp|Q9BWT1|CDCA7_HUMAN Cell division cycle-associated protein 7 OS=Homo sapiens GN=CDCA7 PE=1 SV=1	9031.ENSGALP00000015183	cell division cycle associated 7	_	_	NOG68453	_
ENSGALG00000040855	0.359175855	1.421864761	-1.955515133	2.28E-12	1.23E-11	down	yes	0.363045399	0.375079148	0.339403016	1.49594034	1.455410803	1.314243141	1	36025156	36168865	-	PTPRR	protein_coding	GO:0001701|in utero embryonic development; GO:0006470|protein dephosphorylation; GO:0010633|negative regulation of epithelial cell migration; GO:0038128|ERBB2 signaling pathway; GO:0070373|negative regulation of ERK1 and ERK2 cascade	GO:0005615|extracellular space; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0030054|cell junction; GO:0048471|perinuclear region of cytoplasm	GO:0004725|protein tyrosine phosphatase activity; GO:0005001|transmembrane receptor protein tyrosine phosphatase activity; GO:0019901|protein kinase binding	ko:K04458|PTPRR	ko04010|MAPK signaling pathway	3193	XP_001235188.3	XP_001235188.3 receptor-type tyrosine-protein phosphatase R isoform X1 [Gallus gallus]	sp|Q15256|PTPRR_HUMAN	sp|Q15256|PTPRR_HUMAN Receptor-type tyrosine-protein phosphatase R OS=Homo sapiens GN=PTPRR PE=1 SV=2	13616.ENSMODP00000025509	"protein tyrosine phosphatase, receptor type, R"	COG5599	KOG0789	_	PF00102.24|Y_phosphatase|Protein-tyrosine phosphatase|ENSGALT00000079691|m.896:448-675
ENSGALG00000040880	1.214375767	5.613403043	-2.199397056	7.55E-08	2.72E-07	down	yes	0.693303804	1.101383728	1.848439769	5.128771072	6.078080503	5.633357554	20	10803308	10815864	-	EDN3	protein_coding	GO:0001755|neural crest cell migration; GO:0002690|positive regulation of leukocyte chemotaxis; GO:0003100|regulation of systemic arterial blood pressure by endothelin; GO:0006874|cellular calcium ion homeostasis; GO:0007166|cell surface receptor signaling pathway; GO:0008284|positive regulation of cell population proliferation; GO:0010460|positive regulation of heart rate; GO:0010468|regulation of gene expression; GO:0010961|cellular magnesium ion homeostasis; GO:0014826|vein smooth muscle contraction; GO:0019229|regulation of vasoconstriction; GO:0030072|peptide hormone secretion; GO:0030182|neuron differentiation; GO:0030318|melanocyte differentiation; GO:0030593|neutrophil chemotaxis; GO:0043406|positive regulation of MAP kinase activity; GO:0045597|positive regulation of cell differentiation; GO:0045840|positive regulation of mitotic nuclear division; GO:0046887|positive regulation of hormone secretion; GO:0048016|inositol phosphate-mediated signaling; GO:0048070|regulation of developmental pigmentation; GO:1901381|positive regulation of potassium ion transmembrane transport	GO:0005615|extracellular space; GO:0005622|intracellular	GO:0005179|hormone activity; GO:0031708|endothelin B receptor binding	ko:K05227|EDN3	--	456	XP_015152038.1	XP_015152038.1 endothelin-3 isoform X1 [Gallus gallus]	sp|A5A752|EDN3_PIG	sp|A5A752|EDN3_PIG Endothelin-3 OS=Sus scrofa GN=EDN3 PE=2 SV=1	9031.ENSGALP00000038270	Endothelin 3 Fragment 	_	_	NOG41573	PF00322.14|Endothelin|Endothelin family|ENSGALT00000069693|m.3570:67-95
ENSGALG00000040942	2.221307351	4.628763112	-1.055850923	4.25E-15	2.86E-14	down	yes	2.239636333	2.263964911	2.160320811	5.01971713	4.161537154	4.705035051	19	6306821	6333842	+	EFCAB5	protein_coding	--	--	GO:0005509|calcium ion binding	--	--	3875	XP_015151592.1	XP_015151592.1 EF-hand calcium-binding domain-containing protein 5 isoform X1 [Gallus gallus]	sp|A4FU69|EFCB5_HUMAN	sp|A4FU69|EFCB5_HUMAN EF-hand calcium-binding domain-containing protein 5 OS=Homo sapiens GN=EFCAB5 PE=1 SV=3	9031.ENSGALP00000006625	EF-hand calcium binding domain 5	_	_	NOG41426	_
ENSGALG00000040954	6.937180057	25.09428249	-1.853434097	1.21E-60	6.13E-59	down	yes	6.825159403	8.198726006	5.787654762	23.87239423	24.54858374	26.86186951	1	21985328	21998153	+	GPR37	protein_coding	GO:0007186|G protein-coupled receptor signaling pathway; GO:0007193|adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; GO:0031987|locomotion involved in locomotory behavior; GO:0042416|dopamine biosynthetic process; GO:0043410|positive regulation of MAPK cascade; GO:0045964|positive regulation of dopamine metabolic process; GO:1903206|negative regulation of hydrogen peroxide-induced cell death	GO:0000151|ubiquitin ligase complex; GO:0005783|endoplasmic reticulum; GO:0005789|endoplasmic reticulum membrane; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0043235|receptor complex	GO:0004930|G protein-coupled receptor activity; GO:0008528|G protein-coupled peptide receptor activity; GO:0030544|Hsp70 protein binding; GO:0031072|heat shock protein binding; GO:0031625|ubiquitin protein ligase binding; GO:0036505|prosaposin receptor activity; GO:0042277|peptide binding	ko:K04243|GPR37	ko05012|Parkinson's disease	2455	NP_001075168.1	NP_001075168.1 prosaposin receptor GPR37 precursor [Gallus gallus]	sp|O15354|GPR37_HUMAN	sp|O15354|GPR37_HUMAN Prosaposin receptor GPR37 OS=Homo sapiens GN=GPR37 PE=1 SV=2	59729.ENSTGUP00000004370	Probable G-protein coupled receptor 37 Precursor (Endothelin B receptor-like protein 1)(ETBR [...] 	_	KOG3656	_	PF00001.18|7tm_1|7 transmembrane receptor (rhodopsin family)|ENSGALT00000046405|m.606:144-414
ENSGALG00000040971	4.488200538	2.182556014	1.03673428	3.19E-08	1.20E-07	up	yes	5.541687866	4.096204262	3.826709486	2.389544024	1.84424992	2.313874098	6	8758662	8761245	+	KROX20	protein_coding	"GO:0006355|regulation of transcription, DNA-templated; GO:0006366|transcription by RNA polymerase II; GO:0006611|protein export from nucleus; GO:0007611|learning or memory; GO:0007622|rhythmic behavior; GO:0008045|motor neuron axon guidance; GO:0014037|Schwann cell differentiation; GO:0016925|protein sumoylation; GO:0021569|rhombomere 3 development; GO:0021612|facial nerve structural organization; GO:0021660|rhombomere 3 formation; GO:0021666|rhombomere 5 formation; GO:0030278|regulation of ossification; GO:0032868|response to insulin; GO:0035284|brain segmentation; GO:0035914|skeletal muscle cell differentiation; GO:0042552|myelination; GO:0045444|fat cell differentiation; GO:0045893|positive regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0048168|regulation of neuronal synaptic plasticity; GO:0071310|cellular response to organic substance"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0043231|intracellular membrane-bounded organelle	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0001102|RNA polymerase II activating transcription factor binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003677|DNA binding; GO:0003682|chromatin binding; GO:0003700|DNA-binding transcription factor activity; GO:0016874|ligase activity; GO:0031625|ubiquitin protein ligase binding; GO:0044212|transcription regulatory region DNA binding; GO:0046872|metal ion binding; GO:0071837|HMG box domain binding"	ko:K12496|EGR2	ko05161|Hepatitis B; ko05166|HTLV-I infection; ko05203|Viral carcinogenesis	2339	XP_025007817.1	XP_025007817.1 E3 SUMO-protein ligase EGR2 [Gallus gallus]	sp|P08152|EGR2_MOUSE	sp|P08152|EGR2_MOUSE E3 SUMO-protein ligase EGR2 OS=Mus musculus GN=Egr2 PE=1 SV=3	9796.ENSECAP00000008689	early growth response 2	COG5048	KOG1721	_	"PF11928.5|DUF3446|Domain of unknown function (DUF3446)|ENSGALT00000056002|m.4417:97-194;PF00096.23|zf-C2H2|Zinc finger, C2H2 type|ENSGALT00000056002|m.4417:346-370"
ENSGALG00000041080	62.69672097	158.311976	-1.336169538	5.06E-155	2.18E-152	down	yes	64.02840849	62.19693716	61.86481725	156.1708819	161.5925209	157.172525	2	112915343	113003232	+	CHD7	protein_coding	"GO:0001501|skeletal system development; GO:0001974|blood vessel remodeling; GO:0003222|ventricular trabecula myocardium morphogenesis; GO:0003226|right ventricular compact myocardium morphogenesis; GO:0006338|chromatin remodeling; GO:0006351|transcription, DNA-templated; GO:0006364|rRNA processing; GO:0007512|adult heart development; GO:0007605|sensory perception of sound; GO:0007628|adult walking behavior; GO:0008015|blood circulation; GO:0010880|regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; GO:0016569|covalent chromatin modification; GO:0021553|olfactory nerve development; GO:0021772|olfactory bulb development; GO:0030217|T cell differentiation; GO:0030540|female genitalia development; GO:0035116|embryonic hindlimb morphogenesis; GO:0035909|aorta morphogenesis; GO:0036302|atrioventricular canal development; GO:0040018|positive regulation of multicellular organism growth; GO:0042048|olfactory behavior; GO:0043584|nose development; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0048752|semicircular canal morphogenesis; GO:0050767|regulation of neurogenesis; GO:0050890|cognition; GO:0060021|roof of mouth development; GO:0060041|retina development in camera-type eye; GO:0060123|regulation of growth hormone secretion; GO:0060324|face development; GO:0060384|innervation; GO:0060411|cardiac septum morphogenesis; GO:0060429|epithelium development"	GO:0005634|nucleus	GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0004386|helicase activity; GO:0005524|ATP binding; GO:1990841|promoter-specific chromatin binding	ko:K14437|CHD7	--	9983	NP_001071054.1	NP_001071054.1 chromodomain-helicase-DNA-binding protein 7 [Gallus gallus]	sp|Q06A37|CHD7_CHICK	sp|Q06A37|CHD7_CHICK Chromodomain-helicase-DNA-binding protein 7 OS=Gallus gallus GN=CHD7 PE=2 SV=1	_	_	_	_	_	"PF00176.20|SNF2_N|SNF2 family N-terminal domain|ENSGALT00000047494|m.1830:976-1258;PF07533.13|BRK|BRK domain|ENSGALT00000047494|m.1830:2563-2605;PF07533.13|BRK|BRK domain|ENSGALT00000047494|m.1830:2641-2684;PF00385.21|Chromo|Chromo (CHRromatin Organisation MOdifier) domain|ENSGALT00000047494|m.1830:801-861;PF00385.21|Chromo|Chromo (CHRromatin Organisation MOdifier) domain|ENSGALT00000047494|m.1830:883-934;PF00271.28|Helicase_C|Helicase conserved C-terminal domain|ENSGALT00000047494|m.1830:1292-1404;PF04851.12|ResIII|Type III restriction enzyme, res subunit|ENSGALT00000047494|m.1830:967-1136"
ENSGALG00000041091	2756.397589	708.9798901	1.958952274	3.75E-24	4.46E-23	up	yes	3435.397383	2566.845379	2266.950005	752.7413272	682.0550788	692.1432643	MT	9240	9923	+	ATP6	protein_coding	GO:0015986|ATP synthesis coupled proton transport	"GO:0005753|mitochondrial proton-transporting ATP synthase complex; GO:0016021|integral component of membrane; GO:0045263|proton-transporting ATP synthase complex, coupling factor F(o); GO:0070062|extracellular exosome"	GO:0015078|proton transmembrane transporter activity; GO:0016887|ATPase activity	"ko:K02126|ATPeF0A,MTATP6,ATP6"	ko00190|Oxidative phosphorylation; ko01100|Metabolic pathways; ko05010|Alzheimer's disease; ko05012|Parkinson's disease; ko05016|Huntington's disease	684	NP_006920.1	NP_006920.1 ATP synthase F0 subunit 6 (mitochondrion) [Gallus gallus]	sp|P14092|ATP6_CHICK	sp|P14092|ATP6_CHICK ATP synthase subunit a OS=Gallus gallus GN=MT-ATP6 PE=3 SV=1	9031.ENSGALP00000034617	ATP synthase subunit a (F-ATPase protein 6); Mitochondrial membrane ATP synthase (F(1)F(0) A [...] 	COG0356	KOG4665	_	_
ENSGALG00000041103	3.735308256	1.54601045	1.267232715	2.23E-08	8.51E-08	up	yes	3.929163432	3.644172428	3.632588908	1.717956308	1.195361366	1.724713676	6	3686230	3687798	-	SLC18A3	protein_coding	--	GO:0005887|integral component of plasma membrane; GO:0030121|AP-1 adaptor complex; GO:0030122|AP-2 adaptor complex	GO:0005277|acetylcholine transmembrane transporter activity; GO:0042166|acetylcholine binding; GO:0042910|xenobiotic transmembrane transporter activity	"ko:K14636|SLC18A3,VACHT"	ko04721|Synaptic vesicle cycle; ko04725|Cholinergic synapse	1569	NP_996865.1	NP_996865.1 vesicular acetylcholine transporter [Gallus gallus]	sp|Q08C75|VACHA_DANRE	sp|Q08C75|VACHA_DANRE Probable vesicular acetylcholine transporter-A OS=Danio rerio GN=slc18a3a PE=2 SV=1	9031.ENSGALP00000033646	vesicular acetylcholine transporter 	_	KOG3764	_	PF07690.13|MFS_1|Major Facilitator Superfamily|ENSGALT00000076533|m.4324:44-417
ENSGALG00000041120	0.213131399	0.789222972	-1.840704507	0.000618661	0.001347383	down	yes	0.24556433	0.18004798	0.213781887	0.646580045	1.068317745	0.652771126	3	66578513	66621450	+	METTL24	protein_coding	--	GO:0005576|extracellular region	GO:0008168|methyltransferase activity	--	--	1502	XP_004940364.3	XP_004940364.3 methyltransferase-like protein 24 [Gallus gallus]	sp|Q5JXM2|MET24_HUMAN	sp|Q5JXM2|MET24_HUMAN Methyltransferase-like protein 24 OS=Homo sapiens GN=METTL24 PE=2 SV=1	_	_	_	_	_	PF13383.3|Methyltransf_22|Methyltransferase domain|ENSGALT00000076010|m.12384:29-155;PF05050.9|Methyltransf_21|Methyltransferase FkbM domain|ENSGALT00000076010|m.12384:33-162
ENSGALG00000041122	0.543661669	1.356972975	-1.303908172	0.000140965	0.000338221	down	yes	0.593622785	0.455970682	0.58139154	1.116450675	1.576350738	1.378117513	1	47293203	47318899	+	SLC17A8	protein_coding	GO:0003407|neural retina development; GO:0006811|ion transport; GO:0006814|sodium ion transport; GO:0006836|neurotransmitter transport; GO:0007420|brain development; GO:0007605|sensory perception of sound; GO:0090102|cochlea development	GO:0005771|multivesicular body; GO:0016021|integral component of membrane; GO:0030054|cell junction; GO:0030672|synaptic vesicle membrane; GO:0043204|perikaryon; GO:0043679|axon terminus; GO:0060076|excitatory synapse; GO:0097440|apical dendrite; GO:0097441|basal dendrite; GO:0097451|glial limiting end-foot; GO:1990030|pericellular basket	GO:0005313|L-glutamate transmembrane transporter activity; GO:0015293|symporter activity	ko:K12302|SLC17A6_7_8	ko04721|Synaptic vesicle cycle; ko04723|Retrograde endocannabinoid signaling; ko04724|Glutamatergic synapse; ko05033|Nicotine addiction	1864	XP_005024594.2	XP_005024594.2 vesicular glutamate transporter 3 [Anas platyrhynchos]	sp|Q8NDX2|VGLU3_HUMAN	sp|Q8NDX2|VGLU3_HUMAN Vesicular glutamate transporter 3 OS=Homo sapiens GN=SLC17A8 PE=1 SV=1	9031.ENSGALP00000018888	"solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8"	COG0477	KOG2532	_	PF07690.13|MFS_1|Major Facilitator Superfamily|ENSGALT00000055202|m.1129:111-476
ENSGALG00000041154	11.35706132	27.27055422	-1.263013625	4.89E-27	6.77E-26	down	yes	12.10130276	10.00817821	11.96170299	28.61183668	23.64522285	29.55460313	2	8624610	8627626	-	MNX1	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006357|regulation of transcription by RNA polymerase II; GO:0006959|humoral immune response; GO:0009653|anatomical structure morphogenesis; GO:0021520|spinal cord motor neuron cell fate specification; GO:0031018|endocrine pancreas development; GO:0048812|neuron projection morphogenesis"	GO:0005634|nucleus; GO:0005730|nucleolus; GO:0005829|cytosol	GO:0003700|DNA-binding transcription factor activity; GO:0043565|sequence-specific DNA binding	"ko:K08025|HLXB9,HB9"	ko04950|Maturity onset diabetes of the young	1463	NP_990259.1	NP_990259.1 motor neuron and pancreas homeobox protein 1 [Gallus gallus]	sp|P50219|MNX1_HUMAN	sp|P50219|MNX1_HUMAN Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens GN=MNX1 PE=1 SV=3	9031.ENSGALP00000010375	homeo box HB9 	_	KOG0489	_	PF00046.26|Homeobox|Homeobox domain|ENSGALT00000075435|m.14761:191-247
ENSGALG00000041182	0.422813157	1.294735179	-1.591940751	9.28E-07	2.98E-06	down	yes	0.330697212	0.501099465	0.436642795	1.160984133	1.377649807	1.345571597	15	1219854	1227550	+	TBX1	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0007275|multicellular organism development; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0050793|regulation of developmental process; GO:0060788|ectodermal placode formation; GO:0071300|cellular response to retinoic acid"	GO:0005634|nucleus	GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity	ko:K10175|TBX1	--	2060	XP_025011482.1	XP_025011482.1 T-box transcription factor TBX1 isoform X2 [Gallus gallus]	sp|Q3SA49|TBX1_XENTR	sp|Q3SA49|TBX1_XENTR T-box transcription factor TBX1 OS=Xenopus tropicalis GN=tbx1 PE=2 SV=1	8364.ENSXETP00000013817	T-box transcription factor 1	_	KOG3586	_	PF00907.19|T-box|T-box|ENSGALT00000082478|m.10316:132-317
ENSGALG00000041192	2.80533725	6.795406301	-1.273373544	1.56E-21	1.61E-20	down	yes	2.250755164	2.775863535	3.389393049	6.689746193	7.121323527	6.575149183	7	21044187	21071090	+	IFIH1	protein_coding	GO:0009597|detection of virus; GO:0009615|response to virus; GO:0016032|viral process; GO:0016579|protein deubiquitination; GO:0016925|protein sumoylation; GO:0032480|negative regulation of type I interferon production; GO:0032727|positive regulation of interferon-alpha production; GO:0032728|positive regulation of interferon-beta production; GO:0034344|regulation of type III interferon production; GO:0035549|positive regulation of interferon-beta secretion; GO:0039528|cytoplasmic pattern recognition receptor signaling pathway in response to virus; GO:0039530|MDA-5 signaling pathway; GO:0045087|innate immune response; GO:0051607|defense response to virus; GO:0060760|positive regulation of response to cytokine stimulus; GO:0071360|cellular response to exogenous dsRNA; GO:1902741|positive regulation of interferon-alpha secretion; GO:1904469|positive regulation of tumor necrosis factor secretion; GO:2000778|positive regulation of interleukin-6 secretion	GO:0005634|nucleus; GO:0005829|cytosol	GO:0003677|DNA binding; GO:0003725|double-stranded RNA binding; GO:0003727|single-stranded RNA binding; GO:0004386|helicase activity; GO:0005524|ATP binding; GO:0008270|zinc ion binding; GO:0042802|identical protein binding; GO:0043021|ribonucleoprotein complex binding	"ko:K12647|IFIH1,MDA5"	ko04622|RIG-I-like receptor signaling pathway; ko05161|Hepatitis B; ko05162|Measles; ko05164|Influenza A; ko05168|Herpes simplex infection	4050	AEM00325.1	AEM00325.1 interferon-induced helicase C domain-containing protein 1 [Gallus gallus]	sp|Q9BYX4|IFIH1_HUMAN	sp|Q9BYX4|IFIH1_HUMAN Interferon-induced helicase C domain-containing protein 1 OS=Homo sapiens GN=IFIH1 PE=1 SV=3	_	_	_	_	_	"PF16739.2|CARD_2|Caspase recruitment domain|ENSGALT00000053962|m.6252:108-198;PF16739.2|CARD_2|Caspase recruitment domain|ENSGALT00000053962|m.6252:209-299;PF11648.5|RIG-I_C-RD|C-terminal domain of RIG-I|ENSGALT00000053962|m.6252:979-1094;PF04851.12|ResIII|Type III restriction enzyme, res subunit|ENSGALT00000053962|m.6252:400-584;PF00271.28|Helicase_C|Helicase conserved C-terminal domain|ENSGALT00000053962|m.6252:783-899;PF00270.26|DEAD|DEAD/DEAH box helicase|ENSGALT00000053962|m.6252:404-582;PF00619.18|CARD|Caspase recruitment domain|ENSGALT00000053962|m.6252:217-298"
ENSGALG00000041202	1.664872435	9.901313842	-2.565025095	3.20E-100	3.94E-98	down	yes	1.964791653	1.550749478	1.479076174	9.590297191	9.493941558	10.61970278	2	138061819	138086470	-	FBXO32	protein_coding	GO:0014894|response to denervation involved in regulation of muscle adaptation; GO:0016567|protein ubiquitination; GO:0071549|cellular response to dexamethasone stimulus	GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0019005|SCF ubiquitin ligase complex; GO:0030018|Z disc	--	ko:K10305|FBXO25_32	ko04068|FoxO signaling pathway	4559	NP_001026127.1	NP_001026127.1 F-box only protein 32 [Gallus gallus]	sp|Q1A730|FBX32_PIG	sp|Q1A730|FBX32_PIG F-box only protein 32 OS=Sus scrofa GN=FBXO32 PE=2 SV=1	9031.ENSGALP00000026354	F-box only protein 32 	_	KOG3926	_	_
ENSGALG00000041280	3.130119963	1.163910374	1.419497411	4.58E-05	0.00011825	up	yes	4.541391896	2.848342485	2.000625509	1.008476872	1.363307776	1.119946473	32	549342	554130	+	FOSB	protein_coding	GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0007565|female pregnancy; GO:0009612|response to mechanical stimulus; GO:0032570|response to progesterone; GO:0032870|cellular response to hormone stimulus; GO:0042493|response to drug; GO:0043278|response to morphine; GO:0051412|response to corticosterone; GO:0051591|response to cAMP; GO:0071277|cellular response to calcium ion	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0043231|intracellular membrane-bounded organelle	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003677|DNA binding; GO:0008134|transcription factor binding"	ko:K09029|FOSB	ko04380|Osteoclast differentiation; ko04657|IL-17 signaling pathway; ko05030|Cocaine addiction; ko05031|Amphetamine addiction; ko05034|Alcoholism	963	XP_015128804.2	XP_015128804.2 protein fosB isoform X1 [Gallus gallus]	sp|P53539|FOSB_HUMAN	sp|P53539|FOSB_HUMAN Protein fosB OS=Homo sapiens GN=FOSB PE=1 SV=1	_	_	_	_	_	PF00170.18|bZIP_1|bZIP transcription factor|ENSGALT00000052563|m.14454:153-211;PF07716.12|bZIP_2|Basic region leucine zipper|ENSGALT00000052563|m.14454:155-207
ENSGALG00000041295	9.827592955	3.085957384	1.66791975	7.80E-30	1.22E-28	up	yes	10.17303205	8.861399619	10.44834719	2.812690697	3.79987494	2.645306514	2	7960618	7964289	+	EN2	protein_coding	"GO:0006355|regulation of transcription, DNA-templated; GO:0007411|axon guidance; GO:0042327|positive regulation of phosphorylation; GO:0045727|positive regulation of translation; GO:1901215|negative regulation of neuron death"	GO:0005623|cell; GO:0005634|nucleus; GO:0030027|lamellipodium; GO:0030175|filopodium; GO:0030426|growth cone; GO:0043005|neuron projection	GO:0043565|sequence-specific DNA binding	ko:K09319|EN	ko04341|Hedgehog signaling pathway - fly	2424	NP_001254648.1	NP_001254648.1 homeobox protein engrailed-2 [Gallus gallus]	sp|Q05917|HME2_CHICK	sp|Q05917|HME2_CHICK Homeobox protein engrailed-2 OS=Gallus gallus GN=EN2 PE=1 SV=2	59729.ENSTGUP00000000705	Homeobox protein engrailed-1 (Hu-En-1) [Taeniopygia guttata]	_	KOG0493	_	PF00046.26|Homeobox|Homeobox domain|ENSGALT00000075534|m.14747:201-257;PF10525.6|Engrail_1_C_sig|Engrailed homeobox C-terminal signature domain|ENSGALT00000075534|m.14747:258-288
ENSGALG00000041346	0.457058687	1.007890241	-1.123906259	0.002253855	0.004485067	down	yes	0.461250523	0.517230669	0.392694869	1.000168102	1.094537375	0.928965244	6	19850341	19864037	-	CXCL12	protein_coding	GO:0006952|defense response; GO:0006955|immune response; GO:0007411|axon guidance; GO:0030335|positive regulation of cell migration; GO:0050930|induction of positive chemotaxis; GO:0070098|chemokine-mediated signaling pathway	GO:0005615|extracellular space; GO:0009897|external side of plasma membrane	GO:0008009|chemokine activity; GO:0008083|growth factor activity; GO:0042056|chemoattractant activity; GO:0042379|chemokine receptor binding; GO:0045236|CXCR chemokine receptor binding	ko:K10031|CXCL12	ko04060|Cytokine-cytokine receptor interaction; ko04062|Chemokine signaling pathway; ko04064|NF-kappa B signaling pathway; ko04360|Axon guidance; ko04670|Leukocyte transendothelial migration; ko04672|Intestinal immune network for IgA production; ko05200|Pathways in cancer; ko05323|Rheumatoid arthritis	1363	RMC11569.1	RMC11569.1 hypothetical protein DUI87_11689 [Hirundo rustica rustica]	sp|O62657|SDF1_FELCA	sp|O62657|SDF1_FELCA Stromal cell-derived factor 1 OS=Felis catus GN=CXCL12 PE=3 SV=1	9031.ENSGALP00000010112	stromal cell derived factor 1 	_	_	NOG26489	"PF00048.17|IL8|Small cytokines (intecrine/chemokine), interleukin-8 like|ENSGALT00000066398|m.4853:29-85"
ENSGALG00000041365	3.350866217	9.357829724	-1.478881737	1.05E-42	2.96E-41	down	yes	3.19903196	2.933709485	3.919857207	8.993546867	9.785029288	9.294913017	20	13087625	13101795	+	SALL4	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0001833|inner cell mass cell proliferation; GO:0001843|neural tube closure; GO:0003281|ventricular septum development; GO:0006355|regulation of transcription, DNA-templated; GO:0006366|transcription by RNA polymerase II; GO:0007165|signal transduction; GO:0022008|neurogenesis; GO:0030326|embryonic limb morphogenesis; GO:0035019|somatic stem cell population maintenance; GO:0045944|positive regulation of transcription by RNA polymerase II"	GO:0000792|heterochromatin; GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0032991|protein-containing complex; GO:0043231|intracellular membrane-bounded organelle	GO:0003700|DNA-binding transcription factor activity; GO:0008134|transcription factor binding; GO:0043565|sequence-specific DNA binding; GO:0044212|transcription regulatory region DNA binding; GO:0046872|metal ion binding	ko:K19871|SALL	--	5165	NP_001074341.1	NP_001074341.1 sal-like protein 4 [Gallus gallus]	sp|Q9UJQ4|SALL4_HUMAN	sp|Q9UJQ4|SALL4_HUMAN Sal-like protein 4 OS=Homo sapiens GN=SALL4 PE=1 SV=1	_	_	_	_	_	PF13894.3|zf-C2H2_4|C2H2-type zinc finger|ENSGALT00000077429|m.3646:398-420;PF13894.3|zf-C2H2_4|C2H2-type zinc finger|ENSGALT00000077429|m.3646:597-619;PF13894.3|zf-C2H2_4|C2H2-type zinc finger|ENSGALT00000077429|m.3646:952-974;PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000077429|m.3646:371-392;PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000077429|m.3646:597-616;PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000077429|m.3646:630-649;PF13912.3|zf-C2H2_6|C2H2-type zinc finger|ENSGALT00000077429|m.3646:924-946
ENSGALG00000041449	0.346136263	0.898510573	-1.351073963	0.000224895	0.000522578	down	yes	0.229182278	0.412453583	0.396772927	0.909086712	0.840486984	0.945958024	5	24740037	24756678	-	EXD1	protein_coding	GO:0031047|gene silencing by RNA; GO:0034587|piRNA metabolic process; GO:0051321|meiotic cell cycle	GO:0043186|P granule; GO:1990923|PET complex	GO:0003723|RNA binding; GO:0042803|protein homodimerization activity	"ko:K18740|EXD1,EGL"	--	2457	XP_010709626.1	XP_010709626.1 PREDICTED: piRNA biogenesis protein EXD1 isoform X2 [Meleagris gallopavo]	sp|Q8CDF7|EXD1_MOUSE	sp|Q8CDF7|EXD1_MOUSE piRNA biogenesis protein EXD1 OS=Mus musculus GN=Exd1 PE=1 SV=1	_	_	_	_	_	PF01612.17|DNA_pol_A_exo1|3'-5' exonuclease|ENSGALT00000057381|m.3067:173-262
ENSGALG00000041510	0.12901925	0.381759384	-1.494683161	0.000615983	0.001342518	down	yes	0.101307371	0.148557304	0.137193076	0.372597709	0.244852024	0.527828417	10	1504415	1521465	+	DUOX2	protein_coding	GO:0006590|thyroid hormone generation; GO:0006979|response to oxidative stress; GO:0009566|fertilization; GO:0009615|response to virus; GO:0019221|cytokine-mediated signaling pathway; GO:0030282|bone mineralization; GO:0030878|thyroid gland development; GO:0035264|multicellular organism growth; GO:0042335|cuticle development; GO:0042446|hormone biosynthetic process; GO:0042744|hydrogen peroxide catabolic process; GO:0048839|inner ear development; GO:0048855|adenohypophysis morphogenesis; GO:0050665|hydrogen peroxide biosynthetic process; GO:0051591|response to cAMP; GO:0055114|oxidation-reduction process	GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0016324|apical plasma membrane; GO:0030054|cell junction; GO:0070062|extracellular exosome	GO:0004601|peroxidase activity; GO:0005509|calcium ion binding; GO:0016174|NAD(P)H oxidase activity; GO:0020037|heme binding	"ko:K13411|DUOX,THOX"	ko04013|MAPK signaling pathway - fly; ko04624|Toll and Imd signaling pathway	4681	XP_015134571.1	XP_015134571.1 dual oxidase 2 [Gallus gallus]	sp|Q9NRD8|DUOX2_HUMAN	sp|Q9NRD8|DUOX2_HUMAN Dual oxidase 2 OS=Homo sapiens GN=DUOX2 PE=1 SV=2	9031.ENSGALP00000003834	dual oxidase 2	_	KOG0039	_	PF03098.12|An_peroxidase|Animal haem peroxidase|ENSGALT00000067778|m.5097:41-559;PF08030.9|NAD_binding_6|Ferric reductase NAD binding domain|ENSGALT00000067778|m.5097:1371-1525;PF01794.16|Ferric_reduct|Ferric reductase like transmembrane component|ENSGALT00000067778|m.5097:1078-1227;PF08022.9|FAD_binding_8|FAD-binding domain|ENSGALT00000067778|m.5097:1265-1363;PF00036.29|EF-hand_1|EF hand|ENSGALT00000067778|m.5097:823-847;PF13499.3|EF-hand_7|EF-hand domain pair|ENSGALT00000067778|m.5097:858-927;PF13833.3|EF-hand_8|EF-hand domain pair|ENSGALT00000067778|m.5097:805-846;PF13833.3|EF-hand_8|EF-hand domain pair|ENSGALT00000067778|m.5097:842-883;PF13202.3|EF-hand_5|EF hand|ENSGALT00000067778|m.5097:824-844;PF13202.3|EF-hand_5|EF hand|ENSGALT00000067778|m.5097:862-882
ENSGALG00000041555	0.567297527	1.32904039	-1.213812527	1.92E-06	5.94E-06	down	yes	0.77309255	0.487121361	0.441678671	1.585754365	1.079698325	1.321668482	27	5538288	5555467	+	COL1A1	protein_coding	--	GO:0005581|collagen trimer; GO:0031012|extracellular matrix	GO:0005201|extracellular matrix structural constituent; GO:0046872|metal ion binding	ko:K06236|COL1A	ko04151|PI3K-Akt signaling pathway; ko04510|Focal adhesion; ko04512|ECM-receptor interaction; ko04611|Platelet activation; ko04933|AGE-RAGE signaling pathway in diabetic complications; ko04974|Protein digestion and absorption; ko05146|Amoebiasis	4362	CAA23695.1	"CAA23695.1 collagen, partial [Gallus gallus]"	sp|P02457|CO1A1_CHICK	sp|P02457|CO1A1_CHICK Collagen alpha-1(I) chain OS=Gallus gallus GN=COL1A1 PE=1 SV=3	9544.ENSMMUP00000001955	Collagen type I alpha 1 Fragment 	_	KOG3544	_	PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000070776|m.8947:101-148;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000070776|m.8947:168-225;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000070776|m.8947:225-284;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000070776|m.8947:285-342;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000070776|m.8947:345-393;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000070776|m.8947:537-593;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000070776|m.8947:552-610;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000070776|m.8947:672-729;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000070776|m.8947:705-763;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000070776|m.8947:768-826;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000070776|m.8947:822-878;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000070776|m.8947:1068-1126;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000070776|m.8947:1122-1180;PF01410.15|COLFI|Fibrillar collagen C-terminal domain|ENSGALT00000070776|m.8947:1217-1452;PF00093.15|VWC|von Willebrand factor type C domain|ENSGALT00000070776|m.8947:33-88
ENSGALG00000041565	19.06823926	40.10074886	-1.072060871	4.13E-10	1.85E-09	down	yes	15.75300602	19.38295613	22.06875561	40.59283846	43.25373342	36.4556747	5	51927665	51942266	+	ENSGALG00000041565	protein_coding	--	GO:0005737|cytoplasm; GO:0005874|microtubule	--	ko:K16463|CEP170	--	291	OXB59488.1	OXB59488.1 hypothetical protein ASZ78_008313 [Callipepla squamata]	sp|Q80U49|C170B_MOUSE	sp|Q80U49|C170B_MOUSE Centrosomal protein of 170 kDa protein B OS=Mus musculus GN=Cep170b PE=1 SV=2	59729.ENSTGUP00000013291	K0284_HUMAN Isoform 3 of Q9Y4F5 - Homo sapiens (Human) [Taeniopygia guttata]	_	_	NOG274968	_
ENSGALG00000041621	11.1292535	5.180985442	1.101572206	9.38E-14	5.69E-13	up	yes	10.66569626	12.49346296	10.22860127	4.906963641	5.512286834	5.123705852	2	148338397	148344678	-	LY6E	protein_coding	GO:0002320|lymphoid progenitor cell differentiation; GO:0008283|cell population proliferation	GO:0005886|plasma membrane; GO:0009986|cell surface; GO:0031225|anchored component of membrane	--	ko:K06846|LY6D_E_G6_H	--	1240	NP_990106.1	NP_990106.1 lymphocyte antigen 6E precursor [Gallus gallus]	sp|Q90986|LY6E_CHICK	sp|Q90986|LY6E_CHICK Lymphocyte antigen 6E OS=Gallus gallus GN=LY6E PE=2 SV=1	9031.ENSGALP00000025978	Lymphocyte antigen 6E Precursor (Ly-6E)(Stem cell antigen 2)(SCA-2)	_	_	NOG39378	PF00021.18|UPAR_LY6|u-PAR/Ly-6 domain|ENSGALT00000059872|m.2633:34-107;PF00087.18|Toxin_1|Snake toxin|ENSGALT00000059872|m.2633:32-107
ENSGALG00000041708	0.452896709	2.456797963	-2.41387735	1.14E-11	5.84E-11	down	yes	0.293135405	0.591049618	0.474505103	2.75655879	2.159270403	2.454564695	21	6313309	6325046	+	WNT4	protein_coding	"GO:0001658|branching involved in ureteric bud morphogenesis; GO:0001837|epithelial to mesenchymal transition; GO:0001838|embryonic epithelial tube formation; GO:0001889|liver development; GO:0006702|androgen biosynthetic process; GO:0008584|male gonad development; GO:0008585|female gonad development; GO:0009267|cellular response to starvation; GO:0014858|positive regulation of skeletal muscle cell proliferation; GO:0016055|Wnt signaling pathway; GO:0022407|regulation of cell-cell adhesion; GO:0030182|neuron differentiation; GO:0030237|female sex determination; GO:0030325|adrenal gland development; GO:0030336|negative regulation of cell migration; GO:0030501|positive regulation of bone mineralization; GO:0032349|positive regulation of aldosterone biosynthetic process; GO:0032967|positive regulation of collagen biosynthetic process; GO:0033080|immature T cell proliferation in thymus; GO:0038030|non-canonical Wnt signaling pathway via MAPK cascade; GO:0040037|negative regulation of fibroblast growth factor receptor signaling pathway; GO:0043547|positive regulation of GTPase activity; GO:0045165|cell fate commitment; GO:0045596|negative regulation of cell differentiation; GO:0045669|positive regulation of osteoblast differentiation; GO:0045836|positive regulation of meiotic nuclear division; GO:0045892|negative regulation of transcription, DNA-templated; GO:0045893|positive regulation of transcription, DNA-templated; GO:0048599|oocyte development; GO:0051145|smooth muscle cell differentiation; GO:0051496|positive regulation of stress fiber assembly; GO:0051894|positive regulation of focal adhesion assembly; GO:0060070|canonical Wnt signaling pathway; GO:0060126|somatotropin secreting cell differentiation; GO:0060129|thyroid-stimulating hormone-secreting cell differentiation; GO:0060231|mesenchymal to epithelial transition; GO:0060993|kidney morphogenesis; GO:0061036|positive regulation of cartilage development; GO:0061045|negative regulation of wound healing; GO:0061184|positive regulation of dermatome development; GO:0061205|paramesonephric duct development; GO:0061369|negative regulation of testicular blood vessel morphogenesis; GO:0071560|cellular response to transforming growth factor beta stimulus; GO:0072033|renal vesicle formation; GO:0072034|renal vesicle induction; GO:0072174|metanephric tubule formation; GO:0072273|metanephric nephron morphogenesis; GO:0072659|protein localization to plasma membrane; GO:0090090|negative regulation of canonical Wnt signaling pathway; GO:0090263|positive regulation of canonical Wnt signaling pathway; GO:1902811|positive regulation of skeletal muscle fiber differentiation; GO:2000019|negative regulation of male gonad development; GO:2000066|positive regulation of cortisol biosynthetic process; GO:2000225|negative regulation of testosterone biosynthetic process; GO:2001234|negative regulation of apoptotic signaling pathway"	GO:0005615|extracellular space; GO:0005737|cytoplasm; GO:0009986|cell surface; GO:0031012|extracellular matrix	GO:0003714|transcription corepressor activity; GO:0005109|frizzled binding	ko:K00408|WNT4	ko04150|mTOR signaling pathway; ko04310|Wnt signaling pathway; ko04360|Axon guidance; ko04390|Hippo signaling pathway; ko04550|Signaling pathways regulating pluripotency of stem cells; ko04916|Melanogenesis; ko04919|Thyroid hormone signaling pathway; ko05166|HTLV-I infection; ko05200|Pathways in cancer; ko05205|Proteoglycans in cancer; ko05217|Basal cell carcinoma; ko05224|Breast cancer	1438	NP_990114.1	NP_990114.1 protein Wnt-4 precursor [Gallus gallus]	sp|P49337|WNT4_CHICK	sp|P49337|WNT4_CHICK Protein Wnt-4 OS=Gallus gallus GN=WNT4 PE=1 SV=1	9031.ENSGALP00000007633	Protein Wnt-4 Precursor ; Ligand for members of the frizzled family of seven transmembrane r [...] 	_	KOG3913	_	PF00110.16|wnt|wnt family|ENSGALT00000080352|m.4309:110-416
ENSGALG00000041722	5.117168692	10.28906871	-1.006279618	1.04E-18	9.08E-18	down	yes	5.594613708	4.937287031	4.819605337	10.20827157	9.83220877	10.82672579	19	288961	335181	-	STX1A	protein_coding	GO:0001956|positive regulation of neurotransmitter secretion; GO:0006886|intracellular protein transport; GO:0007269|neurotransmitter secretion; GO:0009629|response to gravity; GO:0010701|positive regulation of norepinephrine secretion; GO:0010807|regulation of synaptic vesicle priming; GO:0014047|glutamate secretion; GO:0016081|synaptic vesicle docking; GO:0031629|synaptic vesicle fusion to presynaptic active zone membrane; GO:0032940|secretion by cell; GO:0033605|positive regulation of catecholamine secretion; GO:0035493|SNARE complex assembly; GO:0045956|positive regulation of calcium ion-dependent exocytosis; GO:0048278|vesicle docking; GO:0050796|regulation of insulin secretion; GO:0072657|protein localization to membrane; GO:2000463|positive regulation of excitatory postsynaptic potential	GO:0005576|extracellular region; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0008021|synaptic vesicle; GO:0008076|voltage-gated potassium channel complex; GO:0014069|postsynaptic density; GO:0016021|integral component of membrane; GO:0030054|cell junction; GO:0030141|secretory granule; GO:0030424|axon; GO:0030672|synaptic vesicle membrane; GO:0031201|SNARE complex; GO:0031965|nuclear membrane; GO:0042641|actomyosin; GO:0043005|neuron projection; GO:0048787|presynaptic active zone membrane; GO:0070032|synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex; GO:0070033|synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex; GO:0070044|synaptobrevin 2-SNAP-25-syntaxin-1a complex	"GO:0000149|SNARE binding; GO:0005484|SNAP receptor activity; GO:0017022|myosin binding; GO:0019855|calcium channel inhibitor activity; GO:0019869|chloride channel inhibitor activity; GO:0019900|kinase binding; GO:0019904|protein domain specific binding; GO:0030674|protein binding, bridging; GO:0032028|myosin head/neck binding; GO:0043008|ATP-dependent protein binding; GO:0044325|ion channel binding; GO:0046982|protein heterodimerization activity; GO:0047485|protein N-terminus binding; GO:0048306|calcium-dependent protein binding"	ko:K04560|STX1A	ko04130|SNARE interactions in vesicular transport; ko04721|Synaptic vesicle cycle; ko04911|Insulin secretion; ko05031|Amphetamine addiction	2590	XP_015151383.2	XP_015151383.2 syntaxin-1A [Gallus gallus]	sp|Q16623|STX1A_HUMAN	sp|Q16623|STX1A_HUMAN Syntaxin-1A OS=Homo sapiens GN=STX1A PE=1 SV=1	_	_	_	_	_	PF00804.22|Syntaxin|Syntaxin|ENSGALT00000047910|m.13467:149-346;PF05739.16|SNARE|SNARE domain|ENSGALT00000047910|m.13467:347-398;PF14523.3|Syntaxin_2|Syntaxin-like protein|ENSGALT00000047910|m.13467:163-265
ENSGALG00000041744	1.878591315	0.761277496	1.291988618	7.81E-07	2.53E-06	up	yes	1.99469708	1.766412568	1.874664297	0.682092448	0.840122379	0.761617662	9	5386182	5392731	+	OTOS	protein_coding	GO:0007605|sensory perception of sound	GO:0005576|extracellular region	--	--	--	2034	NP_001264635.1	NP_001264635.1 otospiralin precursor [Gallus gallus]	sp|Q8K559|OTOSP_CAVPO	sp|Q8K559|OTOSP_CAVPO Otospiralin OS=Cavia porcellus GN=OTOS PE=2 SV=1	9031.ENSGALP00000040203	annotation not avaliable	_	_	NOG40438	PF15182.3|OTOS|Otospiralin|ENSGALT00000065966|m.8609:44-108
ENSGALG00000041775	1.136472823	3.889567376	-1.766111922	8.41E-13	4.73E-12	down	yes	1.553392957	0.956717215	0.899308297	3.973280436	4.22680531	3.468616383	5	38847495	38965455	+	ESRRB	protein_coding	"GO:0006355|regulation of transcription, DNA-templated; GO:0006367|transcription initiation from RNA polymerase II promoter; GO:0008283|cell population proliferation; GO:0017145|stem cell division; GO:0019827|stem cell population maintenance; GO:0043697|cell dedifferentiation; GO:0045494|photoreceptor cell maintenance; GO:0045725|positive regulation of glycogen biosynthetic process; GO:0045821|positive regulation of glycolytic process; GO:0045893|positive regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0048839|inner ear development; GO:0071931|positive regulation of transcription involved in G1/S transition of mitotic cell cycle; GO:0090282|positive regulation of transcription involved in G2/M transition of mitotic cell cycle; GO:1902459|positive regulation of stem cell population maintenance; GO:2000035|regulation of stem cell division; GO:2000737|negative regulation of stem cell differentiation"	GO:0000793|condensed chromosome; GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm	"GO:0000980|RNA polymerase II distal enhancer sequence-specific DNA binding; GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0000993|RNA polymerase II complex binding; GO:0001047|core promoter binding; GO:0001158|enhancer sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003700|DNA-binding transcription factor activity; GO:0003707|steroid hormone receptor activity; GO:0003713|transcription coactivator activity; GO:0004879|nuclear receptor activity; GO:0005496|steroid binding; GO:0008134|transcription factor binding; GO:0008270|zinc ion binding; GO:0035326|enhancer binding; GO:0043565|sequence-specific DNA binding"	"ko:K08553|NR3B2,ESRRB"	ko04550|Signaling pathways regulating pluripotency of stem cells	1694	XP_015143195.1	XP_015143195.1 steroid hormone receptor ERR2 isoform X1 [Gallus gallus]	sp|O95718|ERR2_HUMAN	sp|O95718|ERR2_HUMAN Steroid hormone receptor ERR2 OS=Homo sapiens GN=ESRRB PE=1 SV=3	9031.ENSGALP00000016869	estrogen-related receptor beta	_	KOG3575	_	"PF00104.27|Hormone_recep|Ligand-binding domain of nuclear hormone receptor|ENSGALT00000065675|m.3596:368-545;PF00105.15|zf-C4|Zinc finger, C4 type (two domains)|ENSGALT00000065675|m.3596:232-300"
ENSGALG00000041791	0.574565718	2.246980429	-1.948956779	5.77E-11	2.79E-10	down	yes	0.901803481	0.314858617	0.507035056	2.002964593	2.292814161	2.445162532	2	7565007	7718788	+	DPP6	protein_coding	GO:0072659|protein localization to plasma membrane; GO:1901379|regulation of potassium ion transmembrane transport	GO:0005886|plasma membrane; GO:0008076|voltage-gated potassium channel complex	GO:0008236|serine-type peptidase activity; GO:0015459|potassium channel regulator activity	--	--	2394	XP_004939209.1	XP_004939209.1 dipeptidyl aminopeptidase-like protein 6 isoform X3 [Gallus gallus]	sp|Q5IS50|DPP6_PANTR	sp|Q5IS50|DPP6_PANTR Dipeptidyl aminopeptidase-like protein 6 OS=Pan troglodytes GN=DPP6 PE=2 SV=1	9031.ENSGALP00000010196	dipeptidyl-peptidase 6	COG1506	KOG2100	_	PF00930.18|DPPIV_N|Dipeptidyl peptidase IV (DPP IV) N-terminal region|ENSGALT00000056196|m.14740:129-495;PF00326.18|Peptidase_S9|Prolyl oligopeptidase family|ENSGALT00000056196|m.14740:578-780;PF07676.9|PD40|WD40-like Beta Propeller Repeat|ENSGALT00000056196|m.14740:368-384;PF01738.15|DLH|Dienelactone hydrolase family|ENSGALT00000056196|m.14740:713-763
ENSGALG00000041808	0.286337717	0.691913223	-1.244050423	3.01E-05	7.96E-05	down	yes	0.235639714	0.225353795	0.398019641	0.651277883	0.684778048	0.739683736	5	17981909	18053418	+	ANO1	protein_coding	GO:0006812|cation transport; GO:0006821|chloride transport; GO:0007200|phospholipase C-activating G protein-coupled receptor signaling pathway; GO:0007275|multicellular organism development; GO:0015705|iodide transport; GO:0034220|ion transmembrane transport; GO:0034605|cellular response to heat; GO:0035774|positive regulation of insulin secretion involved in cellular response to glucose stimulus; GO:0050965|detection of temperature stimulus involved in sensory perception of pain; GO:1902476|chloride transmembrane transport	GO:0005737|cytoplasm; GO:0005886|plasma membrane; GO:0016324|apical plasma membrane; GO:0034707|chloride channel complex; GO:0070062|extracellular exosome	GO:0005227|calcium activated cation channel activity; GO:0005229|intracellular calcium activated chloride channel activity; GO:0005247|voltage-gated chloride channel activity; GO:0005254|chloride channel activity; GO:0015111|iodide transmembrane transporter activity; GO:0046983|protein dimerization activity	"ko:K19496|ANO1,DOG1,TMEM16A"	--	4213	XP_004941586.2	XP_004941586.2 anoctamin-1 isoform X1 [Gallus gallus]	sp|Q5XXA6|ANO1_HUMAN	sp|Q5XXA6|ANO1_HUMAN Anoctamin-1 OS=Homo sapiens GN=ANO1 PE=1 SV=1	9031.ENSGALP00000012304	transmembrane protein 16A	_	KOG2514	_	"PF04547.9|Anoctamin|Calcium-activated chloride channel|ENSGALT00000104647|m.2837:382-962;PF16178.2|Anoct_dimer|Dimerisation domain of Ca+-activated chloride-channel, anoctamin|ENSGALT00000104647|m.2837:97-379"
ENSGALG00000041826	28.25635034	8.977422158	1.653106344	3.87E-24	4.60E-23	up	yes	27.92501365	28.25686199	28.58717538	9.981122584	8.34564805	8.605495839	25	3308021	3309315	-	S100A6	protein_coding	GO:0007049|cell cycle; GO:0051781|positive regulation of cell division	GO:0001726|ruffle; GO:0005623|cell; GO:0005635|nuclear envelope; GO:0005829|cytosol; GO:0031234|extrinsic component of cytoplasmic side of plasma membrane; GO:0048471|perinuclear region of cytoplasm; GO:0070062|extracellular exosome	GO:0005509|calcium ion binding; GO:0005523|tropomyosin binding; GO:0008270|zinc ion binding; GO:0019899|enzyme binding; GO:0042803|protein homodimerization activity; GO:0044548|S100 protein binding; GO:0048306|calcium-dependent protein binding	--	--	417	XP_015739966.1	XP_015739966.1 PREDICTED: protein S100-A6 [Coturnix japonica]	sp|Q98953|S10A6_CHICK	sp|Q98953|S10A6_CHICK Protein S100-A6 OS=Gallus gallus GN=S100A6 PE=3 SV=1	_	_	_	_	_	PF01023.16|S_100|S-100/ICaBP type calcium binding domain|ENSGALT00000065566|m.7173:36-71
ENSGALG00000041898	4.991939342	2.075243398	1.262271772	1.18E-08	4.61E-08	up	yes	5.370717071	5.108516006	4.49658495	2.074785104	1.990146784	2.160798305	9	12971183	12972271	-	FAM43A	protein_coding	--	--	--	--	--	1089	XP_426700.2	XP_426700.2 protein FAM43A [Gallus gallus]	sp|Q8N2R8|FA43A_HUMAN	sp|Q8N2R8|FA43A_HUMAN Protein FAM43A OS=Homo sapiens GN=FAM43A PE=2 SV=2	9031.ENSGALP00000011410	"family with sequence similarity 43, member A"	_	KOG4448	_	PF14719.3|PID_2|Phosphotyrosine interaction domain (PTB/PID)|ENSGALT00000082189|m.8830:68-254;PF00640.20|PID|Phosphotyrosine interaction domain (PTB/PID)|ENSGALT00000082189|m.8830:94-199
ENSGALG00000041926	144.4694351	51.34601715	1.492258931	1.74E-51	6.61E-50	up	yes	157.9525546	133.1582534	142.2974971	60.16276393	47.31175477	46.56353275	27	3752626	3757369	+	HEXIM1	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0002218|activation of innate immune response; GO:0006351|transcription, DNA-templated; GO:0007507|heart development; GO:0045087|innate immune response; GO:0045736|negative regulation of cyclin-dependent protein serine/threonine kinase activity; GO:0045892|negative regulation of transcription, DNA-templated; GO:1901798|positive regulation of signal transduction by p53 class mediator"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm	GO:0004861|cyclin-dependent protein serine/threonine kinase inhibitor activity; GO:0017069|snRNA binding; GO:0097322|7SK snRNA binding	ko:K15189|HEXIM1_2	--	873	XP_003642831.2	XP_003642831.2 protein HEXIM1 [Gallus gallus]	sp|Q5M9G1|HEXI1_RAT	sp|Q5M9G1|HEXI1_RAT Protein HEXIM1 OS=Rattus norvegicus GN=Hexim1 PE=1 SV=1	_	_	_	_	_	PF15313.3|HEXIM|Hexamethylene bis-acetamide-inducible protein|ENSGALT00000070961|m.8642:101-238
ENSGALG00000041939	16.05666164	7.934044846	1.016124522	8.29E-20	7.70E-19	up	yes	17.0564416	15.29519507	15.81834824	8.46688145	7.347612532	7.987640557	19	5978442	5985142	-	FAM222B	protein_coding	--	GO:0005654|nucleoplasm	--	--	--	1662	XP_015151244.1	XP_015151244.1 protein FAM222B isoform X1 [Gallus gallus]	sp|Q8WU58|F222B_HUMAN	sp|Q8WU58|F222B_HUMAN Protein FAM222B OS=Homo sapiens GN=FAM222B PE=1 SV=1	59729.ENSTGUP00000006369	Uncharacterized protein C17orf63 [Taeniopygia guttata]	_	_	NOG47137	PF15258.3|FAM222A|Protein family of FAM222A|ENSGALT00000077330|m.13915:27-553
ENSGALG00000041978	1.512269161	3.095898687	-1.028787298	2.12E-06	6.52E-06	down	yes	1.952813362	1.176125086	1.407869035	2.984098033	2.468699427	3.8348986	1	4059566	4071675	+	K123	protein_coding	--	--	--	--	--	2455	NP_990350.1	NP_990350.1 K123 protein precursor [Gallus gallus]	_	_	9031.ENSGALP00000010230	K123 protein 	_	_	NOG119192	PF01223.20|Endonuclease_NS|DNA/RNA non-specific endonuclease|ENSGALT00000102127|m.273:40-256
ENSGALG00000041988	19.43110246	166.2648147	-3.096387725	0	0	down	yes	19.90991232	19.21747769	19.16591737	162.6557228	176.8735818	159.2651395	1	111210237	111222987	-	SIK1	protein_coding	GO:0006468|protein phosphorylation; GO:0032870|cellular response to hormone stimulus; GO:0035556|intracellular signal transduction; GO:0046626|regulation of insulin receptor signaling pathway	GO:0005634|nucleus; GO:0005737|cytoplasm	GO:0000287|magnesium ion binding; GO:0004674|protein serine/threonine kinase activity; GO:0005524|ATP binding	ko:K19008|SIK1	ko04922|Glucagon signaling pathway	5068	XP_025010540.1	XP_025010540.1 serine/threonine-protein kinase SIK2 isoform X1 [Gallus gallus]	sp|Q9IA88|SIK2_CHICK	sp|Q9IA88|SIK2_CHICK Serine/threonine-protein kinase SIK2 OS=Gallus gallus GN=SIK2 PE=2 SV=1	9031.ENSGALP00000026069	Serine/threonine-protein kinase SIK2 (EC 2.7.11.1)(Salt-inducible protein kinase 2)(SIK-2)(S [...] 	COG0515	KOG0586	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000052958|m.3195:26-277;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000052958|m.3195:28-273;PF14531.3|Kinase-like|Kinase-like|ENSGALT00000052958|m.3195:125-265
ENSGALG00000042055	19.23431424	42.47070057	-1.142375296	1.28E-47	4.30E-46	down	yes	20.24703887	19.5550524	17.90085145	42.95278699	41.36739447	43.09192027	17	7577223	7651643	+	RXRA	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0001701|in utero embryonic development; GO:0001890|placenta development; GO:0001893|maternal placenta development; GO:0003007|heart morphogenesis; GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated; GO:0006357|regulation of transcription by RNA polymerase II; GO:0007507|heart development; GO:0007566|embryo implantation; GO:0010629|negative regulation of gene expression; GO:0019048|modulation by virus of host morphology or physiology; GO:0032526|response to retinoic acid; GO:0035357|peroxisome proliferator activated receptor signaling pathway; GO:0043010|camera-type eye development; GO:0045893|positive regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0045994|positive regulation of translational initiation by iron; GO:0048384|retinoic acid receptor signaling pathway; GO:0051289|protein homotetramerization; GO:0055007|cardiac muscle cell differentiation; GO:0055010|ventricular cardiac muscle tissue morphogenesis; GO:0055012|ventricular cardiac muscle cell differentiation; GO:0060038|cardiac muscle cell proliferation; GO:0060485|mesenchyme development; GO:0060528|secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development; GO:0060687|regulation of branching involved in prostate gland morphogenesis; GO:0060978|angiogenesis involved in coronary vascular morphogenesis; GO:0061032|visceral serous pericardium development; GO:1901522|positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus"	GO:0000790|nuclear chromatin; GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0032991|protein-containing complex; GO:0043235|receptor complex; GO:0090575|RNA polymerase II transcription factor complex	GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding; GO:0001972|retinoic acid binding; GO:0003677|DNA binding; GO:0003690|double-stranded DNA binding; GO:0003700|DNA-binding transcription factor activity; GO:0003707|steroid hormone receptor activity; GO:0004879|nuclear receptor activity; GO:0008134|transcription factor binding; GO:0008270|zinc ion binding; GO:0016922|nuclear receptor binding; GO:0019899|enzyme binding; GO:0031490|chromatin DNA binding; GO:0042277|peptide binding; GO:0042809|vitamin D receptor binding; GO:0043565|sequence-specific DNA binding; GO:0044323|retinoic acid-responsive element binding; GO:0046982|protein heterodimerization activity; GO:0050692|DBD domain binding; GO:0050693|LBD domain binding; GO:0070644|vitamin D response element binding	"ko:K08524|RXRA,NR2B1"	ko03320|PPAR signaling pathway; ko04151|PI3K-Akt signaling pathway; ko04659|Th17 cell differentiation; ko04919|Thyroid hormone signaling pathway; ko04920|Adipocytokine signaling pathway; ko04932|Non-alcoholic fatty liver disease (NAFLD); ko04976|Bile secretion; ko05160|Hepatitis C; ko05200|Pathways in cancer; ko05202|Transcriptional misregulation in cancer; ko05216|Thyroid cancer; ko05222|Small cell lung cancer; ko05223|Non-small cell lung cancer	1944	XP_010569111.1	XP_010569111.1 PREDICTED: retinoic acid receptor RXR-alpha isoform X1 [Haliaeetus leucocephalus]	sp|P28700|RXRA_MOUSE	sp|P28700|RXRA_MOUSE Retinoic acid receptor RXR-alpha OS=Mus musculus GN=Rxra PE=1 SV=1	10090.ENSMUSP00000076491	retinoid X receptor alpha Gene; Nuclear hormone receptor. Involved in the retinoic acid resp [...] 	_	KOG3575	_	"PF00104.27|Hormone_recep|Ligand-binding domain of nuclear hormone receptor|ENSGALT00000059924|m.12222:270-447;PF11825.5|Nuc_recep-AF1|Nuclear/hormone receptor activator site AF-1|ENSGALT00000059924|m.12222:18-132;PF00105.15|zf-C4|Zinc finger, C4 type (two domains)|ENSGALT00000059924|m.12222:139-207"
ENSGALG00000042067	9.496041556	38.66700136	-2.024559333	7.62E-58	3.47E-56	down	yes	10.63639997	8.918419215	8.933305479	43.72224696	37.36374599	34.91501112	4	53357901	53358866	-	SPRY1	protein_coding	GO:0000132|establishment of mitotic spindle orientation; GO:0001656|metanephros development; GO:0001657|ureteric bud development; GO:0001759|organ induction; GO:0008285|negative regulation of cell population proliferation; GO:0034260|negative regulation of GTPase activity; GO:0040037|negative regulation of fibroblast growth factor receptor signaling pathway; GO:0042059|negative regulation of epidermal growth factor receptor signaling pathway; GO:0043407|negative regulation of MAP kinase activity; GO:0046580|negative regulation of Ras protein signal transduction; GO:0051387|negative regulation of neurotrophin TRK receptor signaling pathway; GO:0060449|bud elongation involved in lung branching; GO:0060940|epithelial to mesenchymal transition involved in cardiac fibroblast development; GO:0070373|negative regulation of ERK1 and ERK2 cascade	GO:0005654|nucleoplasm; GO:0005794|Golgi apparatus; GO:0005829|cytosol; GO:0005886|plasma membrane	--	ko:K04704|SPRY1	--	966	NP_001090993.1	NP_001090993.1 protein sprouty homolog 1 [Gallus gallus]	sp|O43609|SPY1_HUMAN	sp|O43609|SPY1_HUMAN Protein sprouty homolog 1 OS=Homo sapiens GN=SPRY1 PE=1 SV=2	_	_	_	_	_	PF05210.10|Sprouty|Sprouty protein (Spry)|ENSGALT00000065925|m.747:188-297
ENSGALG00000042082	1.598012866	0.356715839	2.132544467	2.12E-06	6.52E-06	up	yes	2.208007543	1.324565222	1.261465834	0.415269019	0.337395489	0.317483008	2	111223762	111224811	-	MOS	protein_coding	GO:0000186|activation of MAPKK activity; GO:0035556|intracellular signal transduction; GO:0043410|positive regulation of MAPK cascade; GO:0046777|protein autophosphorylation; GO:1902103|negative regulation of metaphase/anaphase transition of meiotic cell cycle	GO:0005737|cytoplasm	GO:0004674|protein serine/threonine kinase activity; GO:0004709|MAP kinase kinase kinase activity; GO:0005524|ATP binding	ko:K04367|MOS	ko04010|MAPK signaling pathway; ko04114|Oocyte meiosis; ko04810|Regulation of actin cytoskeleton; ko04914|Progesterone-mediated oocyte maturation	1050	NP_001026687.1	NP_001026687.1 serine/threonine-protein kinase mos [Gallus gallus]	sp|P10741|MOS_CHICK	sp|P10741|MOS_CHICK Serine/threonine-protein kinase mos OS=Gallus gallus GN=MOS PE=3 SV=1	_	_	_	_	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000063000|m.1794:68-339;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000063000|m.1794:66-340
ENSGALG00000042134	10.46564625	35.91667975	-1.778016365	7.05E-152	2.75E-149	down	yes	10.43144398	10.41476601	10.55072874	36.05399709	33.14949995	38.54654221	2	97729887	98023150	+	PIEZO2	protein_coding	GO:0006812|cation transport; GO:0009612|response to mechanical stimulus; GO:0042391|regulation of membrane potential; GO:0050974|detection of mechanical stimulus involved in sensory perception; GO:0071260|cellular response to mechanical stimulus	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0005261|cation channel activity; GO:0008381|mechanosensitive ion channel activity	--	--	8502	XP_025003589.1	XP_025003589.1 piezo-type mechanosensitive ion channel component 2 isoform X4 [Gallus gallus]	sp|Q8CD54|PIEZ2_MOUSE	sp|Q8CD54|PIEZ2_MOUSE Piezo-type mechanosensitive ion channel component 2 OS=Mus musculus GN=Piezo2 PE=1 SV=2	_	_	_	_	_	"PF12166.5|Piezo_RRas_bdg|Piezo non-specific cation channel, R-Ras-binding domain|ENSGALT00000065142|m.1494:2426-2830;PF15917.2|PIEZO|Piezo|ENSGALT00000065142|m.1494:1367-1631"
ENSGALG00000042148	27.40841953	72.97569775	-1.412468369	1.18E-92	1.24E-90	down	yes	26.54959782	28.97486422	26.70079655	72.28546415	76.38923208	70.25239702	26	76711	94225	-	FKBP51	protein_coding	GO:0006457|protein folding; GO:0061077|chaperone-mediated protein folding	GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0016020|membrane; GO:0070062|extracellular exosome	GO:0003755|peptidyl-prolyl cis-trans isomerase activity; GO:0005528|FK506 binding; GO:0031072|heat shock protein binding	ko:K09571|FKBP4_5	ko04915|Estrogen signaling pathway	2270	XP_015740262.1	XP_015740262.1 PREDICTED: peptidyl-prolyl cis-trans isomerase FKBP5 isoform X1 [Coturnix japonica]	sp|Q13451|FKBP5_HUMAN	sp|Q13451|FKBP5_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP5 OS=Homo sapiens GN=FKBP5 PE=1 SV=2	9031.ENSGALP00000001396	FK506 binding protein 5 	COG0545	KOG0543	_	PF00254.25|FKBP_C|FKBP-type peptidyl-prolyl cis-trans isomerase|ENSGALT00000090967|m.7429:45-135;PF00254.25|FKBP_C|FKBP-type peptidyl-prolyl cis-trans isomerase|ENSGALT00000090967|m.7429:159-247;PF00515.25|TPR_1|Tetratricopeptide repeat|ENSGALT00000090967|m.7429:319-350;PF07719.14|TPR_2|Tetratricopeptide repeat|ENSGALT00000090967|m.7429:319-350;PF13181.3|TPR_8|Tetratricopeptide repeat|ENSGALT00000090967|m.7429:319-350
ENSGALG00000042182	9.635082602	26.8327234	-1.476665553	1.24E-74	8.74E-73	down	yes	8.694972397	10.35963713	9.850638276	25.522346	28.58527274	26.39055148	2	131316861	131581649	+	OXR1	protein_coding	GO:0006979|response to oxidative stress; GO:0007628|adult walking behavior; GO:0043524|negative regulation of neuron apoptotic process; GO:0051402|neuron apoptotic process; GO:0071447|cellular response to hydroperoxide; GO:1900408|negative regulation of cellular response to oxidative stress; GO:1902083|negative regulation of peptidyl-cysteine S-nitrosylation; GO:1903204|negative regulation of oxidative stress-induced neuron death	GO:0005730|nucleolus; GO:0005739|mitochondrion	GO:0016491|oxidoreductase activity	--	--	4103	XP_021245004.1	XP_021245004.1 oxidation resistance protein 1 isoform X4 [Numida meleagris]	sp|Q4V8B0|OXR1_RAT	sp|Q4V8B0|OXR1_RAT Oxidation resistance protein 1 OS=Rattus norvegicus GN=Oxr1 PE=1 SV=3	9031.ENSGALP00000025863	oxidation resistance 1	COG5142	KOG2372	_	PF07534.13|TLD|TLD|ENSGALT00000097956|m.2399:740-875;PF01476.17|LysM|LysM domain|ENSGALT00000097956|m.2399:117-159
ENSGALG00000042351	0.036531268	1.011835172	-4.456818189	1.47E-06	4.60E-06	down	yes	0.08524342	0	0.024350384	1.306614441	0.939762729	0.789128348	18	1955815	1973637	-	PIK3R6	protein_coding	GO:0001525|angiogenesis; GO:0006661|phosphatidylinositol biosynthetic process; GO:0007186|G protein-coupled receptor signaling pathway; GO:0014065|phosphatidylinositol 3-kinase signaling; GO:0030168|platelet activation; GO:0042269|regulation of natural killer cell mediated cytotoxicity; GO:0043406|positive regulation of MAP kinase activity; GO:0045582|positive regulation of T cell differentiation; GO:0045766|positive regulation of angiogenesis	"GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0005942|phosphatidylinositol 3-kinase complex; GO:0005944|phosphatidylinositol 3-kinase complex, class IB; GO:0016020|membrane"	"GO:0046934|phosphatidylinositol-4,5-bisphosphate 3-kinase activity; GO:0046935|1-phosphatidylinositol-3-kinase regulator activity"	ko:K21290|PIK3R5_6	ko04022|cGMP-PKG signaling pathway; ko04072|Phospholipase D signaling pathway; ko04151|PI3K-Akt signaling pathway; ko04261|Adrenergic signaling in cardiomyocytes; ko04371|Apelin signaling pathway; ko04611|Platelet activation; ko04725|Cholinergic synapse; ko04921|Oxytocin signaling pathway; ko05145|Toxoplasmosis	4554	XP_001232431.3	XP_001232431.3 phosphoinositide 3-kinase regulatory subunit 6 isoform X2 [Gallus gallus]	sp|Q5UE93|PI3R6_HUMAN	sp|Q5UE93|PI3R6_HUMAN Phosphoinositide 3-kinase regulatory subunit 6 OS=Homo sapiens GN=PIK3R6 PE=1 SV=1	9031.ENSGALP00000001859	chromosome 17 open reading frame 38	_	_	NOG28373	PF10486.6|PI3K_1B_p101|Phosphoinositide 3-kinase gamma adapter protein p101 subunit|ENSGALT00000081881|m.12556:106-370;PF10486.6|PI3K_1B_p101|Phosphoinositide 3-kinase gamma adapter protein p101 subunit|ENSGALT00000081881|m.12556:495-824
ENSGALG00000042356	0.474801855	5.173742987	-3.418527066	2.78E-22	2.99E-21	down	yes	0.540976274	0.594966411	0.28846288	5.494155626	4.792572717	5.234500616	28	2836616	2844024	+	FSTL3	protein_coding	"GO:0001503|ossification; GO:0002244|hematopoietic progenitor cell differentiation; GO:0006351|transcription, DNA-templated; GO:0022409|positive regulation of cell-cell adhesion; GO:0030514|negative regulation of BMP signaling pathway; GO:0032926|negative regulation of activin receptor signaling pathway; GO:0045671|negative regulation of osteoclast differentiation; GO:0045944|positive regulation of transcription by RNA polymerase II"	GO:0005615|extracellular space; GO:0005654|nucleoplasm	GO:0001968|fibronectin binding; GO:0048185|activin binding	--	--	974	XP_001233761.2	XP_001233761.2 follistatin-related protein 3 [Gallus gallus]	sp|Q1LZB9|FSTL3_BOVIN	sp|Q1LZB9|FSTL3_BOVIN Follistatin-related protein 3 OS=Bos taurus GN=FSTL3 PE=2 SV=1	_	_	_	_	_	PF07648.12|Kazal_2|Kazal-type serine protease inhibitor domain|ENSGALT00000099617|m.10014:113-155;PF07648.12|Kazal_2|Kazal-type serine protease inhibitor domain|ENSGALT00000099617|m.10014:194-231
ENSGALG00000042360	14.24313268	4.145876221	1.778054452	9.89E-88	9.34E-86	up	yes	14.71447451	14.05102058	13.96390294	3.846481717	4.378790695	4.212356251	24	3898255	3922124	+	TRIM29	protein_coding	GO:0000122|negative regulation of transcription by RNA polymerase II; GO:1900181|negative regulation of protein localization to nucleus	GO:0005737|cytoplasm; GO:0005913|cell-cell adherens junction	GO:0002039|p53 binding; GO:0008270|zinc ion binding; GO:0042802|identical protein binding; GO:0098641|cadherin binding involved in cell-cell adhesion	"ko:K12010|TRIM29,ATDC"	--	4050	XP_015153675.1	XP_015153675.1 tripartite motif-containing protein 29 isoform X2 [Gallus gallus]	sp|Q8R2Q0|TRI29_MOUSE	sp|Q8R2Q0|TRI29_MOUSE Tripartite motif-containing protein 29 OS=Mus musculus GN=Trim29 PE=1 SV=1	9031.ENSGALP00000040041	tripartite motif-containing 29	_	KOG2177	_	PF00643.21|zf-B_box|B-box zinc finger|ENSGALT00000049607|m.6227:240-278
ENSGALG00000042389	0.96775743	0.477783697	1.003235053	0.006770846	0.0123658	up	yes	1.08942746	0.720840461	1.093004367	0.409786165	0.420355686	0.603209239	7	28518095	28521131	+	EN1	protein_coding	"GO:0006355|regulation of transcription, DNA-templated; GO:0007275|multicellular organism development"	GO:0005634|nucleus	GO:0043565|sequence-specific DNA binding	ko:K09319|EN	ko04341|Hedgehog signaling pathway - fly	1983	XP_001234329.4	XP_001234329.4 homeobox protein engrailed-1 [Gallus gallus]	sp|Q05916|HME1_CHICK	sp|Q05916|HME1_CHICK Homeobox protein engrailed-1 OS=Gallus gallus GN=EN1 PE=3 SV=1	_	_	_	_	_	PF00046.26|Homeobox|Homeobox domain|ENSGALT00000050873|m.6648:246-302;PF10525.6|Engrail_1_C_sig|Engrailed homeobox C-terminal signature domain|ENSGALT00000050873|m.6648:303-333
ENSGALG00000042422	3.280459869	7.421925641	-1.17544684	1.81E-23	2.08E-22	down	yes	3.514882495	2.930682491	3.395814622	6.441287982	7.972017381	7.852471558	33	5544436	5553014	-	GLI1	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0007224|smoothened signaling pathway; GO:0007275|multicellular organism development; GO:0008284|positive regulation of cell population proliferation; GO:0010628|positive regulation of gene expression; GO:0030154|cell differentiation; GO:0045893|positive regulation of transcription, DNA-templated"	GO:0005634|nucleus; GO:0005737|cytoplasm	GO:0003682|chromatin binding; GO:0043565|sequence-specific DNA binding; GO:0046872|metal ion binding	ko:K16797|GLI1	ko04024|cAMP signaling pathway; ko04340|Hedgehog signaling pathway; ko05200|Pathways in cancer; ko05217|Basal cell carcinoma	4917	NP_001292174.1	NP_001292174.1 zinc finger protein GLI1 [Gallus gallus]	sp|P55878|GLI1_CHICK	sp|P55878|GLI1_CHICK Zinc finger protein GLI1 (Fragment) OS=Gallus gallus GN=GLI1 PE=2 SV=1	9031.ENSGALP00000023546	Zinc finger protein GLI1 Fragment (GLI); May regulate the transcription of specific genes du [...] 	COG5048	KOG1721	_	_
ENSGALG00000042478	4507.235297	1811.330684	1.315188048	5.69E-05	0.000144531	up	yes	6492.890502	3810.243424	3218.571964	1769.555095	1838.334305	1826.102652	MT	11196	11492	+	ND4L	protein_coding	GO:0042773|ATP synthesis coupled electron transport	GO:0005747|mitochondrial respiratory chain complex I; GO:0016021|integral component of membrane	GO:0008137|NADH dehydrogenase (ubiquinone) activity	ko:K03882|ND4L	ko00190|Oxidative phosphorylation; ko01100|Metabolic pathways; ko04723|Retrograde endocannabinoid signaling; ko05012|Parkinson's disease	297	NP_006923.1	NP_006923.1 NADH dehydrogenase subunit 4L (mitochondrion) [Gallus gallus]	sp|P18942|NU4LM_CHICK	sp|P18942|NU4LM_CHICK NADH-ubiquinone oxidoreductase chain 4L OS=Gallus gallus GN=MT-ND4L PE=3 SV=1	9031.ENSGALP00000034620	NADH-ubiquinone oxidoreductase chain 4L (EC 1.6.5.3)(NADH dehydrogenase subunit 4L); Core su [...] 	_	KOG4669	_	_
ENSGALG00000042491	251.5699167	115.2409917	1.126237594	3.53E-31	5.93E-30	up	yes	241.1178438	269.021525	244.5703814	132.5866757	96.71386746	116.422432	1	48135982	48136474	+	ENSGALG00000042491	protein_coding	"GO:0006334|nucleosome assembly; GO:0006335|DNA replication-dependent nucleosome assembly; GO:0006336|DNA replication-independent nucleosome assembly; GO:0006352|DNA-templated transcription, initiation; GO:0045653|negative regulation of megakaryocyte differentiation; GO:0051290|protein heterotetramerization"	"GO:0000784|nuclear chromosome, telomeric region; GO:0000788|nuclear nucleosome; GO:0005654|nucleoplasm; GO:0016020|membrane; GO:0031012|extracellular matrix; GO:0032991|protein-containing complex; GO:0070062|extracellular exosome"	GO:0003677|DNA binding; GO:0003723|RNA binding; GO:0019904|protein domain specific binding; GO:0042393|histone binding; GO:0046982|protein heterodimerization activity	ko:K11254|H4	ko05034|Alcoholism; ko05203|Viral carcinogenesis; ko05322|Systemic lupus erythematosus	493	XP_020834794.1	XP_020834794.1 uncharacterized protein LOC110202808 [Phascolarctos cinereus]	sp|P62803|H4_BOVIN	sp|P62803|H4_BOVIN Histone H4 OS=Bos taurus PE=1 SV=2	9031.ENSGALP00000019191	"Histone H4 ; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin,  [...] "	COG2036	KOG3467	_	PF15511.3|CENP-T_C|Centromere kinetochore component CENP-T histone fold|ENSGALT00000080967|m.1197:44-105;PF02969.14|TAF|TATA box binding protein associated factor (TAF)|ENSGALT00000080967|m.1197:68-101
ENSGALG00000042553	18.18788044	8.56654272	1.085302318	4.46E-08	1.65E-07	up	yes	18.74444906	18.5049553	17.31423694	7.938966531	8.697565378	9.063096252	9	23486507	23490259	-	RAP2B	protein_coding	GO:0030336|negative regulation of cell migration; GO:0031532|actin cytoskeleton reorganization; GO:0031954|positive regulation of protein autophosphorylation; GO:0032486|Rap protein signal transduction; GO:0034613|cellular protein localization; GO:0046328|regulation of JNK cascade; GO:0048814|regulation of dendrite morphogenesis; GO:0061097|regulation of protein tyrosine kinase activity; GO:0070527|platelet aggregation	GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0005923|bicellular tight junction; GO:0030496|midbody; GO:0044291|cell-cell contact zone; GO:0045121|membrane raft; GO:0055038|recycling endosome membrane; GO:0070062|extracellular exosome	GO:0003924|GTPase activity; GO:0005525|GTP binding; GO:0019003|GDP binding; GO:0019904|protein domain specific binding	ko:K07838|RAP2B	--	357	XP_015727679.1	XP_015727679.1 PREDICTED: ras-related protein Rap-2b [Coturnix japonica]	sp|Q06AU2|RAP2A_PIG	sp|Q06AU2|RAP2A_PIG Ras-related protein Rap-2a OS=Sus scrofa GN=RAP2A PE=2 SV=1	_	_	_	_	_	PF00071.19|Ras|Ras family|ENSGALT00000074162|m.9363:1-98
ENSGALG00000042570	0.427373265	6.349072945	-3.861879517	3.19E-33	5.96E-32	down	yes	0.607640237	0.509168399	0.165311158	6.08956534	6.07665003	6.881003465	1	176815363	176825041	-	ENSGALG00000042570	protein_coding	--	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005874|microtubule	GO:0008017|microtubule binding; GO:0042803|protein homodimerization activity	--	--	1214	KQK74104.1	KQK74104.1 microtubule-associated tumor suppressor candidate 2 [Amazona aestiva]	sp|Q5JR59|MTUS2_HUMAN	sp|Q5JR59|MTUS2_HUMAN Microtubule-associated tumor suppressor candidate 2 OS=Homo sapiens GN=MTUS2 PE=1 SV=3	9031.ENSGALP00000027552	KIAA0774	_	_	NOG119660	_
ENSGALG00000042577	0.460259872	1.079719044	-1.212426085	2.95E-06	8.88E-06	down	yes	0.329603448	0.574997306	0.476178863	0.970462101	1.029370469	1.239324563	1	84357507	84390333	+	CFAP44	protein_coding	GO:0060285|cilium-dependent cell motility	GO:0042995|cell projection	--	--	--	4493	XP_015152018.1	XP_015152018.1 cilia- and flagella-associated protein 44 isoform X1 [Gallus gallus]	sp|Q96MT7|CFA44_HUMAN	sp|Q96MT7|CFA44_HUMAN Cilia- and flagella-associated protein 44 OS=Homo sapiens GN=CFAP44 PE=1 SV=1	9031.ENSGALP00000024379	WD repeat domain 52	_	KOG2106	_	"PF00400.29|WD40|WD domain, G-beta repeat|ENSGALT00000081992|m.2663:551-582"
ENSGALG00000042679	24.69286684	57.63001381	-1.222392201	3.72E-63	2.02E-61	down	yes	26.02736165	25.41327329	22.63796559	58.03872389	58.55762859	56.29368895	2	75668730	75718107	+	RETREG1	protein_coding	GO:0019233|sensory perception of pain; GO:0043524|negative regulation of neuron apoptotic process; GO:0061709|reticulophagy	GO:0005783|endoplasmic reticulum; GO:0005794|Golgi apparatus; GO:0005801|cis-Golgi network; GO:0016604|nuclear body; GO:0030176|integral component of endoplasmic reticulum membrane	--	--	--	2234	XP_003640826.1	XP_003640826.1 reticulophagy regulator 1 isoform X1 [Gallus gallus]	sp|Q9H6L5|RETR1_HUMAN	sp|Q9H6L5|RETR1_HUMAN Reticulophagy regulator 1 OS=Homo sapiens GN=RETREG1 PE=1 SV=1	9031.ENSGALP00000021112	hypothetical protein LOC777533	_	_	NOG87326	_
ENSGALG00000042684	3.372245593	1.32900523	1.336819825	0.000965054	0.002037879	up	yes	2.171854927	4.707982717	3.236899135	1.065572995	1.26976797	1.651674726	16	1991627	1993010	-	ENSGALG00000042684	protein_coding	GO:0007166|cell surface receptor signaling pathway; GO:0050776|regulation of immune response	GO:0005783|endoplasmic reticulum; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0009986|cell surface; GO:0016020|membrane	GO:0004888|transmembrane signaling receptor activity; GO:0030246|carbohydrate binding	--	--	558	NP_001026644.1	NP_001026644.1 C-type lectin [Gallus gallus]	sp|Q9UHP7|CLC2D_HUMAN	sp|Q9UHP7|CLC2D_HUMAN C-type lectin domain family 2 member D OS=Homo sapiens GN=CLEC2D PE=1 SV=1	9031.ENSGALP00000023440	C-type lectin 	_	KOG4297	_	PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000053927|m.11365:89-160
ENSGALG00000042726	0.266631222	1.32049652	-2.265928838	3.52E-09	1.45E-08	down	yes	0.217931894	0.213050472	0.368911298	1.120320725	1.264138592	1.577030243	4	64610177	64635020	-	TRMT9B	protein_coding	GO:0002098|tRNA wobble uridine modification; GO:0006400|tRNA modification	GO:0005634|nucleus; GO:0005737|cytoplasm	GO:0000049|tRNA binding; GO:0008175|tRNA methyltransferase activity; GO:0008198|ferrous iron binding; GO:0016300|tRNA (uracil) methyltransferase activity; GO:0016706|2-oxoglutarate-dependent dioxygenase activity	--	--	2144	XP_420694.2	XP_420694.2 probable tRNA methyltransferase 9B isoform X2 [Gallus gallus]	sp|Q9P272|K1456_HUMAN	sp|Q9P272|K1456_HUMAN Probable tRNA methyltransferase 9-like protein OS=Homo sapiens GN=KIAA1456 PE=2 SV=3	9031.ENSGALP00000022260	chromosome 8 open reading frame 79	COG0500	KOG1331	_	PF08241.9|Methyltransf_11|Methyltransferase domain|ENSGALT00000101194|m.1060:50-138;PF13649.3|Methyltransf_25|Methyltransferase domain|ENSGALT00000101194|m.1060:48-135;PF13847.3|Methyltransf_31|Methyltransferase domain|ENSGALT00000101194|m.1060:48-153;PF13489.3|Methyltransf_23|Methyltransferase domain|ENSGALT00000101194|m.1060:30-153;PF01209.15|Ubie_methyltran|ubiE/COQ5 methyltransferase family|ENSGALT00000101194|m.1060:9-140;PF05148.12|Methyltransf_8|Hypothetical methyltransferase|ENSGALT00000101194|m.1060:27-139
ENSGALG00000042739	0.986421072	2.114498897	-1.092295158	0.000147584	0.000353191	down	yes	0.803972017	0.906881509	1.24840969	1.837738214	2.250235035	2.255523442	22	2694182	2712580	+	TACC1	protein_coding	GO:0000226|microtubule cytoskeleton organization; GO:0007049|cell cycle; GO:0008283|cell population proliferation; GO:0021987|cerebral cortex development; GO:0051301|cell division	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005815|microtubule organizing center; GO:0015630|microtubule cytoskeleton; GO:0016020|membrane; GO:0030496|midbody	--	ko:K14281|TACC1	--	1676	XP_024998698.1	XP_024998698.1 transforming acidic coiled-coil-containing protein 1 isoform X7 [Gallus gallus]	sp|O75410|TACC1_HUMAN	sp|O75410|TACC1_HUMAN Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens GN=TACC1 PE=1 SV=2	9031.ENSGALP00000039913	"transforming, acidic coiled-coil containing protein 1"	_	_	NOG83363	PF05010.11|TACC|Transforming acidic coiled-coil-containing protein (TACC)|ENSGALT00000107617|m.4768:1-161
ENSGALG00000042744	12.73104668	150.4097132	-3.561437946	1.98E-81	1.66E-79	down	yes	13.94443709	10.22407338	14.02462955	152.5608249	170.633867	128.0344476	8	3955424	3958244	-	RGS2	protein_coding	GO:0006417|regulation of translation; GO:0007049|cell cycle; GO:0008277|regulation of G protein-coupled receptor signaling pathway; GO:0045744|negative regulation of G protein-coupled receptor signaling pathway	GO:0005634|nucleus; GO:0005730|nucleolus; GO:0005737|cytoplasm; GO:0005886|plasma membrane	GO:0005096|GTPase activator activity	ko:K18154|RGS2	ko04022|cGMP-PKG signaling pathway; ko04740|Olfactory transduction; ko04921|Oxytocin signaling pathway	1451	NP_989726.1	NP_989726.1 regulator of G-protein signaling 2 [Gallus gallus]	sp|Q0P5H5|RGS2_BOVIN	sp|Q0P5H5|RGS2_BOVIN Regulator of G-protein signaling 2 OS=Bos taurus GN=RGS2 PE=2 SV=1	9031.ENSGALP00000003997	"regulator of G-protein signalling 2, 24kDa "	_	KOG3589	_	PF00615.16|RGS|Regulator of G protein signaling domain|ENSGALT00000066127|m.6976:98-212
ENSGALG00000042750	14751.1672	3632.837669	2.021657314	7.47E-19	6.57E-18	up	yes	19208.90132	13211.30975	11833.29053	3733.454331	3671.898009	3493.160668	MT	4050	5024	+	ND1	protein_coding	GO:0045333|cellular respiration	GO:0005747|mitochondrial respiratory chain complex I; GO:0016021|integral component of membrane	GO:0008137|NADH dehydrogenase (ubiquinone) activity	ko:K03878|ND1	ko00190|Oxidative phosphorylation; ko01100|Metabolic pathways; ko04723|Retrograde endocannabinoid signaling; ko05012|Parkinson's disease	975	NP_006915.1	NP_006915.1 NADH dehydrogenase subunit 1 (mitochondrion) [Gallus gallus]	sp|P18936|NU1M_CHICK	sp|P18936|NU1M_CHICK NADH-ubiquinone oxidoreductase chain 1 OS=Gallus gallus GN=MT-ND1 PE=3 SV=1	9031.ENSGALP00000034612	NADH-ubiquinone oxidoreductase chain 1 (EC 1.6.5.3)(NADH dehydrogenase subunit 1); Core subu [...] 	COG1005	KOG4770	_	_
ENSGALG00000042767	6.52666653	3.157629275	1.045151601	3.35E-09	1.38E-08	up	yes	6.627193983	5.840451772	7.112353836	3.155918234	3.692684066	2.624285525	30	1128565	1137195	-	LPAR2	protein_coding	--	GO:0005886|plasma membrane; GO:0009986|cell surface; GO:0016021|integral component of membrane	GO:0070915|lysophosphatidic acid receptor activity	"ko:K04291|LPAR2,EDG4"	ko04015|Rap1 signaling pathway; ko04072|Phospholipase D signaling pathway; ko04080|Neuroactive ligand-receptor interaction; ko04151|PI3K-Akt signaling pathway; ko05200|Pathways in cancer	1434	NP_001108553.2	NP_001108553.2 lysophosphatidic acid receptor 2 [Gallus gallus]	sp|Q95KH4|LPAR2_MACFA	sp|Q95KH4|LPAR2_MACFA Lysophosphatidic acid receptor 2 OS=Macaca fascicularis GN=LPAR2 PE=2 SV=1	28377.ENSACAP00000004732	lysophosphatidic acid receptor 2	_	KOG3656	_	PF00001.18|7tm_1|7 transmembrane receptor (rhodopsin family)|ENSGALT00000069872|m.13760:63-309
ENSGALG00000042794	4.402394122	8.894591179	-1.012987717	8.04E-10	3.50E-09	down	yes	4.250463377	4.379140351	4.577578637	9.992525615	9.245735016	7.445512907	2	121404192	121410278	-	ZFAND1	protein_coding	--	--	GO:0008270|zinc ion binding	--	--	1438	XP_418311.3	XP_418311.3 AN1-type zinc finger protein 1 [Gallus gallus]	sp|Q8TCF1|ZFAN1_HUMAN	sp|Q8TCF1|ZFAN1_HUMAN AN1-type zinc finger protein 1 OS=Homo sapiens GN=ZFAND1 PE=1 SV=1	9031.ENSGALP00000025403	"zinc finger, AN1-type domain 1"	_	KOG3183	_	PF01428.13|zf-AN1|AN1-like Zinc finger|ENSGALT00000076574|m.2028:18-54;PF01428.13|zf-AN1|AN1-like Zinc finger|ENSGALT00000076574|m.2028:72-110
ENSGALG00000042810	6.781546825	2.673952042	1.339381303	5.36E-20	5.03E-19	up	yes	7.245024752	6.04913832	7.050477405	2.177554498	3.064175171	2.780126457	14	15043163	15046202	+	ENSGALG00000042810	protein_coding	--	--	--	--	--	3040	ADD81836.1	ADD81836.1 unknown [Gallus gallus]	_	_	_	_	_	_	_	_
ENSGALG00000042851	13.21347975	42.2716474	-1.676929718	2.77E-82	2.37E-80	down	yes	12.43119398	13.2354318	13.97381345	40.67434198	46.97294977	39.16765045	4	73938490	74100704	+	PPARGC1A	protein_coding	"GO:0000302|response to reactive oxygen species; GO:0000422|autophagy of mitochondrion; GO:0001659|temperature homeostasis; GO:0001678|cellular glucose homeostasis; GO:0001933|negative regulation of protein phosphorylation; GO:0002021|response to dietary excess; GO:0002931|response to ischemia; GO:0006012|galactose metabolic process; GO:0006094|gluconeogenesis; GO:0006355|regulation of transcription, DNA-templated; GO:0006367|transcription initiation from RNA polymerase II promoter; GO:0006397|mRNA processing; GO:0007005|mitochondrion organization; GO:0007568|aging; GO:0007586|digestion; GO:0007623|circadian rhythm; GO:0008209|androgen metabolic process; GO:0008380|RNA splicing; GO:0009409|response to cold; GO:0010822|positive regulation of mitochondrion organization; GO:0014732|skeletal muscle atrophy; GO:0014850|response to muscle activity; GO:0014878|response to electrical stimulus involved in regulation of muscle adaptation; GO:0014912|negative regulation of smooth muscle cell migration; GO:0019395|fatty acid oxidation; GO:0021549|cerebellum development; GO:0022904|respiratory electron transport chain; GO:0030521|androgen receptor signaling pathway; GO:0030900|forebrain development; GO:0032922|circadian regulation of gene expression; GO:0034599|cellular response to oxidative stress; GO:0035066|positive regulation of histone acetylation; GO:0035865|cellular response to potassium ion; GO:0042493|response to drug; GO:0042594|response to starvation; GO:0042752|regulation of circadian rhythm; GO:0043201|response to leucine; GO:0043524|negative regulation of neuron apoptotic process; GO:0045333|cellular respiration; GO:0045722|positive regulation of gluconeogenesis; GO:0045820|negative regulation of glycolytic process; GO:0045893|positive regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0046321|positive regulation of fatty acid oxidation; GO:0048661|positive regulation of smooth muscle cell proliferation; GO:0048662|negative regulation of smooth muscle cell proliferation; GO:0050821|protein stabilization; GO:0050873|brown fat cell differentiation; GO:0051091|positive regulation of DNA-binding transcription factor activity; GO:0051552|flavone metabolic process; GO:0060612|adipose tissue development; GO:0065003|protein-containing complex assembly; GO:0071222|cellular response to lipopolysaccharide; GO:0071250|cellular response to nitrite; GO:0071313|cellular response to caffeine; GO:0071332|cellular response to fructose stimulus; GO:0071333|cellular response to glucose stimulus; GO:0071354|cellular response to interleukin-6; GO:0071356|cellular response to tumor necrosis factor; GO:0071372|cellular response to follicle-stimulating hormone stimulus; GO:0071392|cellular response to estradiol stimulus; GO:0071456|cellular response to hypoxia; GO:0071560|cellular response to transforming growth factor beta stimulus; GO:0071871|response to epinephrine; GO:0071873|response to norepinephrine; GO:0090258|negative regulation of mitochondrial fission; GO:0097009|energy homeostasis; GO:0097067|cellular response to thyroid hormone stimulus; GO:1901215|negative regulation of neuron death; GO:1901558|response to metformin; GO:1901857|positive regulation of cellular respiration; GO:1901860|positive regulation of mitochondrial DNA metabolic process; GO:1901863|positive regulation of muscle tissue development; GO:1904635|positive regulation of glomerular visceral epithelial cell apoptotic process; GO:1904637|cellular response to ionomycin; GO:1904639|cellular response to resveratrol; GO:1904640|response to methionine; GO:1990845|adaptive thermogenesis; GO:2000184|positive regulation of progesterone biosynthetic process; GO:2000272|negative regulation of signaling receptor activity; GO:2000310|regulation of NMDA receptor activity; GO:2001171|positive regulation of ATP biosynthetic process"	"GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005665|RNA polymerase II, core complex; GO:0005719|nuclear euchromatin; GO:0016605|PML body; GO:0022626|cytosolic ribosome; GO:0043025|neuronal cell body; GO:0043231|intracellular membrane-bounded organelle; GO:0097440|apical dendrite; GO:1990843|subsarcolemmal mitochondrion; GO:1990844|interfibrillar mitochondrion"	GO:0003677|DNA binding; GO:0003712|transcription coregulator activity; GO:0003713|transcription coactivator activity; GO:0003723|RNA binding; GO:0008134|transcription factor binding; GO:0016922|nuclear receptor binding; GO:0030331|estrogen receptor binding; GO:0030374|nuclear receptor transcription coactivator activity; GO:0031490|chromatin DNA binding; GO:0031625|ubiquitin protein ligase binding; GO:0042975|peroxisome proliferator activated receptor binding; GO:0043014|alpha-tubulin binding; GO:0043565|sequence-specific DNA binding; GO:0050681|androgen receptor binding; GO:1990841|promoter-specific chromatin binding	"ko:K07202|PPARGC1A,PGC1A"	ko04152|AMPK signaling pathway; ko04211|Longevity regulating pathway; ko04371|Apelin signaling pathway; ko04910|Insulin signaling pathway; ko04920|Adipocytokine signaling pathway; ko04922|Glucagon signaling pathway; ko04931|Insulin resistance; ko05016|Huntington's disease	2388	NP_001006457.1	NP_001006457.1 peroxisome proliferator-activated receptor gamma coactivator 1-alpha [Gallus gallus]	sp|Q9UBK2|PRGC1_HUMAN	sp|Q9UBK2|PRGC1_HUMAN Peroxisome proliferator-activated receptor gamma coactivator 1-alpha OS=Homo sapiens GN=PPARGC1A PE=1 SV=1	9031.ENSGALP00000023218	"peroxisome proliferator-activated receptor gamma, coactivator 1 alpha "	_	_	NOG78353	"PF00076.19|RRM_1|RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)|ENSGALT00000056953|m.1283:676-736"
ENSGALG00000043044	1.572667126	6.019549918	-1.929692461	4.18E-24	4.95E-23	down	yes	1.402424425	1.636820141	1.678756814	5.436679598	6.678483738	5.943486418	1	135111322	135129457	+	IL1R1	protein_coding	GO:0009314|response to radiation; GO:0010286|heat acclimation; GO:0019221|cytokine-mediated signaling pathway; GO:0030728|ovulation; GO:0050727|regulation of inflammatory response; GO:0070498|interleukin-1-mediated signaling pathway; GO:0070555|response to interleukin-1; GO:0070849|response to epidermal growth factor; GO:0071333|cellular response to glucose stimulus; GO:0071559|response to transforming growth factor beta; GO:0071731|response to nitric oxide; GO:1990834|response to odorant; GO:2000391|positive regulation of neutrophil extravasation; GO:2000661|positive regulation of interleukin-1-mediated signaling pathway; GO:2001224|positive regulation of neuron migration	GO:0005615|extracellular space; GO:0005634|nucleus; GO:0005886|plasma membrane; GO:0009986|cell surface; GO:0014069|postsynaptic density; GO:0016020|membrane; GO:0016021|integral component of membrane; GO:0030424|axon; GO:0032991|protein-containing complex	"GO:0002020|protease binding; GO:0004908|interleukin-1 receptor activity; GO:0004909|interleukin-1, type I, activating receptor activity; GO:0005161|platelet-derived growth factor receptor binding; GO:0019966|interleukin-1 binding; GO:0035255|ionotropic glutamate receptor binding"	"ko:K04386|IL1R1,CD121a"	ko04010|MAPK signaling pathway; ko04060|Cytokine-cytokine receptor interaction; ko04064|NF-kappa B signaling pathway; ko04380|Osteoclast differentiation; ko04640|Hematopoietic cell lineage; ko04659|Th17 cell differentiation; ko04750|Inflammatory mediator regulation of TRP channels; ko05146|Amoebiasis; ko05166|HTLV-I infection; ko05418|Fluid shear stress and atherosclerosis	1841	NP_990816.1	NP_990816.1 interleukin-1 receptor type 1 precursor [Gallus gallus]	sp|Q02955|IL1R1_RAT	sp|Q02955|IL1R1_RAT Interleukin-1 receptor type 1 OS=Rattus norvegicus GN=Il1r1 PE=2 SV=1	9031.ENSGALP00000035792	"interleukin 1 receptor, type I "	_	_	NOG40914	PF01582.17|TIR|TIR domain|ENSGALT00000079162|m.3713:389-547
ENSGALG00000043064	34.57662705	1.867024875	4.203694652	1.56E-93	1.65E-91	up	yes	43.51264132	28.31436194	31.90287787	2.634096443	1.398238612	1.568739569	17	865358	868425	-	EXFABP	protein_coding	GO:0002062|chondrocyte differentiation; GO:0003415|chondrocyte hypertrophy; GO:0006915|apoptotic process; GO:0006953|acute-phase response; GO:0006954|inflammatory response; GO:0007507|heart development; GO:0008283|cell population proliferation; GO:0008284|positive regulation of cell population proliferation; GO:0009636|response to toxic substance; GO:0009792|embryo development ending in birth or egg hatching; GO:0010831|positive regulation of myotube differentiation; GO:0015908|fatty acid transport; GO:0015909|long-chain fatty acid transport; GO:0030154|cell differentiation; GO:0032332|positive regulation of chondrocyte differentiation; GO:0032496|response to lipopolysaccharide; GO:0034097|response to cytokine; GO:0042493|response to drug; GO:0042742|defense response to bacterium; GO:0043066|negative regulation of apoptotic process; GO:0044255|cellular lipid metabolic process; GO:0045087|innate immune response; GO:0045663|positive regulation of myoblast differentiation; GO:0048747|muscle fiber development; GO:0051412|response to corticosterone; GO:0055089|fatty acid homeostasis; GO:0070543|response to linoleic acid; GO:0071399|cellular response to linoleic acid	GO:0005615|extracellular space; GO:0005623|cell	GO:0005504|fatty acid binding; GO:0015245|fatty acid transmembrane transporter activity; GO:0050544|arachidonic acid binding; GO:0070538|oleic acid binding; GO:0070539|linoleic acid binding; GO:0070540|stearic acid binding	--	--	775	P21760.2	P21760.2 RecName: Full=Extracellular fatty acid-binding protein; Short=Ex-FABP; AltName: Full=Protein Ch21; AltName: Full=Quiescence-specific protein; AltName: Full=p20K; Flags: Precursor	sp|P21760|EXFAB_CHICK	sp|P21760|EXFAB_CHICK Extracellular fatty acid-binding protein OS=Gallus gallus GN=EXFABP PE=1 SV=2	_	_	_	_	_	PF00061.20|Lipocalin|Lipocalin / cytosolic fatty-acid binding protein family|ENSGALT00000069086|m.11670:31-165
ENSGALG00000043167	1.041296388	2.286117584	-1.127027064	1.91E-06	5.91E-06	down	yes	1.245547062	0.929543977	0.948798125	2.585172744	2.278318061	1.994861947	2	136321689	136339558	-	TNFRSF11B	protein_coding	GO:0001501|skeletal system development; GO:0006954|inflammatory response; GO:0006955|immune response; GO:0007165|signal transduction; GO:0007584|response to nutrient; GO:0030198|extracellular matrix organization; GO:0032026|response to magnesium ion; GO:0032496|response to lipopolysaccharide; GO:0033209|tumor necrosis factor-mediated signaling pathway; GO:0042127|regulation of cell population proliferation; GO:0042489|negative regulation of odontogenesis of dentin-containing tooth; GO:0042493|response to drug; GO:0042981|regulation of apoptotic process; GO:0043627|response to estrogen; GO:0045779|negative regulation of bone resorption; GO:0046685|response to arsenic-containing substance; GO:0097190|apoptotic signaling pathway	GO:0005576|extracellular region; GO:0005615|extracellular space; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0031012|extracellular matrix	GO:0005031|tumor necrosis factor-activated receptor activity; GO:0005125|cytokine activity; GO:0038023|signaling receptor activity	"ko:K05148|TNFRSF11B,OPG"	ko04060|Cytokine-cytokine receptor interaction; ko04380|Osteoclast differentiation	2295	NP_001028813.1	NP_001028813.1 tumor necrosis factor receptor superfamily member 11B precursor [Gallus gallus]	sp|O00300|TR11B_HUMAN	sp|O00300|TR11B_HUMAN Tumor necrosis factor receptor superfamily member 11B OS=Homo sapiens GN=TNFRSF11B PE=1 SV=3	9031.ENSGALP00000030174	"tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) "	_	_	NOG80702	PF00020.15|TNFR_c6|TNFR/NGFR cysteine-rich region|ENSGALT00000081930|m.2447:39-62;PF00020.15|TNFR_c6|TNFR/NGFR cysteine-rich region|ENSGALT00000081930|m.2447:65-105;PF00020.15|TNFR_c6|TNFR/NGFR cysteine-rich region|ENSGALT00000081930|m.2447:107-142;PF00531.19|Death|Death domain|ENSGALT00000081930|m.2447:222-274;PF00531.19|Death|Death domain|ENSGALT00000081930|m.2447:284-364
ENSGALG00000043198	2.099665893	0.881604013	1.242539522	6.94E-26	9.05E-25	up	yes	2.184718171	1.921517229	2.192762279	0.865864573	0.845506248	0.93344122	7	22137902	22168699	-	ENSGALG00000043198	protein_coding	GO:0001701|in utero embryonic development; GO:0055013|cardiac muscle cell development; GO:0060541|respiratory system development; GO:0072358|cardiovascular system development	GO:0005634|nucleus	GO:0004674|protein serine/threonine kinase activity; GO:0005524|ATP binding	ko:K08809|SPEG	--	11239	XP_015145586.1	XP_015145586.1 striated muscle preferentially expressed protein kinase isoform X4 [Gallus gallus]	sp|Q62407|SPEG_MOUSE	sp|Q62407|SPEG_MOUSE Striated muscle-specific serine/threonine-protein kinase OS=Mus musculus GN=Speg PE=1 SV=2	59729.ENSTGUP00000006295	similar to striated muscle-specific serine/threonine protein kinase [Taeniopygia guttata]	COG0515	KOG0032;KOG4475	_	PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000107475|m.6332:54-136;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000107475|m.6332:759-848;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000107475|m.6332:918-1010;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000107475|m.6332:1022-1109;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000107475|m.6332:1115-1204;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000107475|m.6332:1241-1330;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000107475|m.6332:1443-1532;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000107475|m.6332:1537-1626;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000107475|m.6332:2707-2797;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000107475|m.6332:1652-1904;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000107475|m.6332:3099-3343;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000107475|m.6332:64-123;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000107475|m.6332:759-835;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000107475|m.6332:918-997;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000107475|m.6332:1119-1191;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000107475|m.6332:1246-1317;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000107475|m.6332:1547-1613;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000107475|m.6332:2706-2784;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000107475|m.6332:766-843;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000107475|m.6332:1562-1626;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000107475|m.6332:1654-1860;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000107475|m.6332:3098-3337;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000107475|m.6332:924-1003;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000107475|m.6332:1123-1199;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000107475|m.6332:2714-2789;PF00041.18|fn3|Fibronectin type III domain|ENSGALT00000107475|m.6332:1338-1424;PF16650.2|SPEG_u2|Unstructured region on SPEG complex protein|ENSGALT00000107475|m.6332:868-911
ENSGALG00000043372	1.006892267	2.447760241	-1.273177342	1.62E-12	8.87E-12	down	yes	0.99638322	1.138797037	0.885496545	2.755792228	2.64255971	1.944928786	23	2591781	2635428	+	RUNX3	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0001503|ossification; GO:0002062|chondrocyte differentiation; GO:0006355|regulation of transcription, DNA-templated; GO:0006357|regulation of transcription by RNA polymerase II; GO:0006366|transcription by RNA polymerase II; GO:0006468|protein phosphorylation; GO:0030097|hemopoiesis; GO:0045595|regulation of cell differentiation; GO:0045786|negative regulation of cell cycle; GO:0045893|positive regulation of transcription, DNA-templated; GO:0048935|peripheral nervous system neuron development; GO:0050680|negative regulation of epithelial cell proliferation; GO:0071559|response to transforming growth factor beta"	GO:0000790|nuclear chromatin; GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005730|nucleolus; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0043231|intracellular membrane-bounded organelle	"GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding; GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0003700|DNA-binding transcription factor activity; GO:0005524|ATP binding"	"ko:K09279|RUNX3,AML2"	ko04658|Th1 and Th2 cell differentiation	5212	XP_015153219.1	XP_015153219.1 runt-related transcription factor 3 [Gallus gallus]	sp|Q13761|RUNX3_HUMAN	sp|Q13761|RUNX3_HUMAN Runt-related transcription factor 3 OS=Homo sapiens GN=RUNX3 PE=1 SV=2	59729.ENSTGUP00000001161	Runt-related transcription factor 3 (Core-binding factor subunit alpha-3)(CBF-alpha-3)(Acute [...] 	_	KOG3982	_	PF00853.16|Runt|Runt domain|ENSGALT00000104344|m.5383:268-380;PF08504.8|RunxI|Runx inhibition domain|ENSGALT00000104344|m.5383:515-607
ENSGALG00000043386	2.458410044	5.10109597	-1.050050611	2.18E-10	1.01E-09	down	yes	2.575128415	2.668737494	2.131364223	5.187758149	5.111855031	5.003674731	9	17441931	17531426	+	PEX5L	protein_coding	"GO:0016560|protein import into peroxisome matrix, docking; GO:0043949|regulation of cAMP-mediated signaling"	GO:0005778|peroxisomal membrane; GO:0005829|cytosol; GO:0043235|receptor complex	GO:0000268|peroxisome targeting sequence binding; GO:0005052|peroxisome matrix targeting signal-1 binding; GO:0031267|small GTPase binding	"ko:K13342|PEX5,PXR1"	ko04146|Peroxisome	1818	XP_426710.4	XP_426710.4 PEX5-related protein isoform X2 [Gallus gallus]	sp|Q8IYB4|PEX5R_HUMAN	sp|Q8IYB4|PEX5R_HUMAN PEX5-related protein OS=Homo sapiens GN=PEX5L PE=1 SV=2	9031.ENSGALP00000014497	peroxisomal biogenesis factor 5-like	COG0457	KOG1125	_	PF13181.3|TPR_8|Tetratricopeptide repeat|ENSGALT00000077172|m.9197:339-372;PF13181.3|TPR_8|Tetratricopeptide repeat|ENSGALT00000077172|m.9197:488-518;PF13181.3|TPR_8|Tetratricopeptide repeat|ENSGALT00000077172|m.9197:522-553;PF13432.3|TPR_16|Tetratricopeptide repeat|ENSGALT00000077172|m.9197:466-519
ENSGALG00000043400	7.192651123	3.34891812	1.100531398	1.44E-08	5.57E-08	up	yes	7.678246942	6.843439411	7.056267017	4.239498974	2.451662724	3.355592662	33	5164024	5168544	+	BCDIN3D	protein_coding	GO:0001510|RNA methylation; GO:0010586|miRNA metabolic process; GO:2000632|negative regulation of pre-miRNA processing	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005829|cytosol	GO:0008171|O-methyltransferase activity; GO:0008173|RNA methyltransferase activity	--	--	1496	XP_428854.6	XP_428854.6 pre-miRNA 5'-monophosphate methyltransferase [Gallus gallus]	sp|Q29S19|BN3D2_BOVIN	sp|Q29S19|BN3D2_BOVIN Pre-miRNA 5'-monophosphate methyltransferase OS=Bos taurus GN=BCDIN3D PE=2 SV=1	9031.ENSGALP00000040462	BCDIN3 domain containing	_	KOG2899	_	PF06859.9|Bin3|Bicoid-interacting protein 3 (Bin3)|ENSGALT00000080067|m.15089:155-260
ENSGALG00000043451	19.98290751	7.09773504	1.492026487	2.00E-06	6.16E-06	up	yes	12.01399453	24.88303136	23.05169665	7.4448967	6.700550397	7.147758023	1	50795054	50799331	+	DNAL4	protein_coding	"GO:0007017|microtubule-based process; GO:2000582|positive regulation of ATP-dependent microtubule motor activity, plus-end-directed"	GO:0005737|cytoplasm; GO:0005874|microtubule; GO:0005929|cilium; GO:0030286|dynein complex	GO:0003774|motor activity; GO:0008092|cytoskeletal protein binding; GO:0045505|dynein intermediate chain binding; GO:0051959|dynein light intermediate chain binding	ko:K10412|DNAL4	ko05016|Huntington's disease	1915	NP_001006242.1	"NP_001006242.1 dynein light chain 4, axonemal [Gallus gallus]"	sp|Q9DCM4|DNAL4_MOUSE	"sp|Q9DCM4|DNAL4_MOUSE Dynein light chain 4, axonemal OS=Mus musculus GN=Dnal4 PE=3 SV=2"	9031.ENSGALP00000019896	"dynein light chain 4, axonemal "	_	KOG3430	_	PF01221.15|Dynein_light|Dynein light chain type 1|ENSGALT00000101497|m.1360:22-105
ENSGALG00000043493	35.74100641	116.9362736	-1.709790132	2.50E-96	2.85E-94	down	yes	32.62422844	37.87922324	36.71956755	118.9882703	126.5382728	105.2822779	2	54916522	54922765	+	IGFBP1	protein_coding	GO:0007568|aging; GO:0008286|insulin receptor signaling pathway; GO:0030307|positive regulation of cell growth; GO:0042246|tissue regeneration; GO:0043567|regulation of insulin-like growth factor receptor signaling pathway	GO:0005615|extracellular space; GO:0005794|Golgi apparatus	GO:0005520|insulin-like growth factor binding; GO:0031994|insulin-like growth factor I binding; GO:0031995|insulin-like growth factor II binding	--	--	1691	NP_001001294.1	NP_001001294.1 insulin-like growth factor-binding protein 1 precursor [Gallus gallus]	sp|P47876|IBP1_MOUSE	sp|P47876|IBP1_MOUSE Insulin-like growth factor-binding protein 1 OS=Mus musculus GN=Igfbp1 PE=2 SV=2	9031.ENSGALP00000020307	insulin-like growth factor binding protein 1 	_	_	NOG44381	PF00086.15|Thyroglobulin_1|Thyroglobulin type-1 repeat|ENSGALT00000047713|m.762:216-291;PF00219.15|IGFBP|Insulin-like growth factor binding protein|ENSGALT00000047713|m.762:64-118
ENSGALG00000043535	2.042884876	5.721126203	-1.481165941	2.08E-28	3.03E-27	down	yes	1.979804744	1.897441457	2.251408427	5.723551178	5.324437671	6.11538976	2	124171738	124191159	+	RIPK2	protein_coding	GO:0000165|MAPK cascade; GO:0002250|adaptive immune response; GO:0006915|apoptotic process; GO:0006954|inflammatory response; GO:0007249|I-kappaB kinase/NF-kappaB signaling; GO:0010800|positive regulation of peptidyl-threonine phosphorylation; GO:0032755|positive regulation of interleukin-6 production; GO:0032760|positive regulation of tumor necrosis factor production; GO:0033138|positive regulation of peptidyl-serine phosphorylation; GO:0043065|positive regulation of apoptotic process; GO:0045087|innate immune response; GO:0050731|positive regulation of peptidyl-tyrosine phosphorylation; GO:0050852|T cell receptor signaling pathway; GO:0051092|positive regulation of NF-kappaB transcription factor activity; GO:0070431|nucleotide-binding oligomerization domain containing 2 signaling pathway; GO:0071225|cellular response to muramyl dipeptide	GO:0005737|cytoplasm; GO:0005856|cytoskeleton; GO:0031982|vesicle; GO:0032991|protein-containing complex	GO:0004674|protein serine/threonine kinase activity; GO:0004715|non-membrane spanning protein tyrosine kinase activity; GO:0005524|ATP binding	ko:K08846|RIPK2	ko04621|NOD-like receptor signaling pathway; ko04722|Neurotrophin signaling pathway; ko05131|Shigellosis; ko05152|Tuberculosis	3265	NP_001026114.1	NP_001026114.1 receptor-interacting serine/threonine-protein kinase 2 [Gallus gallus]	sp|Q3SZJ2|RIPK2_BOVIN	sp|Q3SZJ2|RIPK2_BOVIN Receptor-interacting serine/threonine-protein kinase 2 OS=Bos taurus GN=RIPK2 PE=2 SV=1	9031.ENSGALP00000025574	receptor-interacting serine-threonine kinase 2 	COG0515	KOG0192	_	PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000056899|m.2079:71-332;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000056899|m.2079:71-332;PF00619.18|CARD|Caspase recruitment domain|ENSGALT00000056899|m.2079:520-599
ENSGALG00000043572	9.067283044	4.461401414	1.021533476	1.14E-16	8.59E-16	up	yes	8.222933696	9.565662818	9.413252619	4.095256212	4.587516235	4.701431796	3	40687395	40693437	-	FAM89A	protein_coding	--	--	--	--	--	2294	XP_015139869.1	XP_015139869.1 protein FAM89A [Gallus gallus]	sp|Q96GI7|FA89A_HUMAN	sp|Q96GI7|FA89A_HUMAN Protein FAM89A OS=Homo sapiens GN=FAM89A PE=1 SV=1	28377.ENSACAP00000002197	microRNA 1182	_	_	NOG43383	_
ENSGALG00000043591	0.920810779	0.449620489	1.018044806	0.001506253	0.003085279	up	yes	0.784093588	0.962954317	1.015384431	0.567750611	0.379880031	0.401230824	5	25782297	25801921	-	PLA2G4F	protein_coding	GO:0001516|prostaglandin biosynthetic process; GO:0006644|phospholipid metabolic process; GO:0009395|phospholipid catabolic process; GO:0036148|phosphatidylglycerol acyl-chain remodeling; GO:0036149|phosphatidylinositol acyl-chain remodeling; GO:0036150|phosphatidylserine acyl-chain remodeling; GO:0036151|phosphatidylcholine acyl-chain remodeling; GO:0036152|phosphatidylethanolamine acyl-chain remodeling; GO:0050482|arachidonic acid secretion; GO:0071236|cellular response to antibiotic; GO:0071407|cellular response to organic cyclic compound	GO:0005765|lysosomal membrane; GO:0005829|cytosol; GO:0031982|vesicle; GO:0032587|ruffle membrane	"GO:0004622|lysophospholipase activity; GO:0004623|phospholipase A2 activity; GO:0008970|phospholipase A1 activity; GO:0046872|metal ion binding; GO:0047498|calcium-dependent phospholipase A2 activity; GO:0102567|phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine); GO:0102568|phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)"	"ko:K16342|PLA2G4,CPLA2"	ko00564|Glycerophospholipid metabolism; ko00565|Ether lipid metabolism; ko00590|Arachidonic acid metabolism; ko00591|Linoleic acid metabolism; ko00592|alpha-Linolenic acid metabolism; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko04010|MAPK signaling pathway; ko04014|Ras signaling pathway; ko04072|Phospholipase D signaling pathway; ko04270|Vascular smooth muscle contraction; ko04370|VEGF signaling pathway; ko04611|Platelet activation; ko04664|Fc epsilon RI signaling pathway; ko04724|Glutamatergic synapse; ko04726|Serotonergic synapse; ko04730|Long-term depression; ko04750|Inflammatory mediator regulation of TRP channels; ko04912|GnRH signaling pathway; ko04913|Ovarian steroidogenesis; ko04921|Oxytocin signaling pathway; ko05231|Choline metabolism in cancer	2688	XP_426428.2	XP_426428.2 cytosolic phospholipase A2 zeta isoform X1 [Gallus gallus]	sp|Q68DD2|PA24F_HUMAN	sp|Q68DD2|PA24F_HUMAN Cytosolic phospholipase A2 zeta OS=Homo sapiens GN=PLA2G4F PE=2 SV=3	9031.ENSGALP00000014562	"phospholipase A2, group IVF"	_	KOG1028;KOG1325	_	PF01735.15|PLA2_B|Lysophospholipase catalytic domain|ENSGALT00000070336|m.3130:355-504;PF01735.15|PLA2_B|Lysophospholipase catalytic domain|ENSGALT00000070336|m.3130:555-616;PF00168.27|C2|C2 domain|ENSGALT00000070336|m.3130:45-145
ENSGALG00000043727	3.048048283	7.789292309	-1.350732038	2.05E-18	1.75E-17	down	yes	3.771283399	3.00019844	2.372663011	9.079941706	7.173830828	7.114104393	33	3308221	3313864	+	NR4A1	protein_coding	"GO:0006351|transcription, DNA-templated"	GO:0005634|nucleus	GO:0003707|steroid hormone receptor activity; GO:0004879|nuclear receptor activity; GO:0008270|zinc ion binding; GO:0043565|sequence-specific DNA binding	"ko:K04465|NR4A1,HMR"	ko04010|MAPK signaling pathway; ko04151|PI3K-Akt signaling pathway; ko04925|Aldosterone synthesis and secretion	3234	XP_015129004.2	XP_015129004.2 nuclear receptor subfamily 4 group A member 1 [Gallus gallus]	sp|Q04913|NR4A1_XENLA	sp|Q04913|NR4A1_XENLA Nuclear receptor subfamily 4 group A member 1 OS=Xenopus laevis GN=nr4a1 PE=2 SV=1	_	_	_	_	_	"PF00105.15|zf-C4|Zinc finger, C4 type (two domains)|ENSGALT00000063699|m.14772:226-294;PF00104.27|Hormone_recep|Ligand-binding domain of nuclear hormone receptor|ENSGALT00000063699|m.14772:356-475"
ENSGALG00000043768	2927.550143	1149.068594	1.349221331	4.04E-11	1.98E-10	up	yes	3679.907121	2793.076517	2309.666791	1198.164119	1118.915035	1130.126629	MT	5241	6279	+	ND2	protein_coding	"GO:0006120|mitochondrial electron transport, NADH to ubiquinone; GO:0072593|reactive oxygen species metabolic process"	GO:0005747|mitochondrial respiratory chain complex I; GO:0016021|integral component of membrane	GO:0008137|NADH dehydrogenase (ubiquinone) activity	ko:K03879|ND2	ko00190|Oxidative phosphorylation; ko01100|Metabolic pathways; ko04723|Retrograde endocannabinoid signaling; ko05012|Parkinson's disease	1039	NP_006916.1	NP_006916.1 NADH dehydrogenase subunit 2 (mitochondrion) [Gallus gallus]	sp|P18937|NU2M_CHICK	sp|P18937|NU2M_CHICK NADH-ubiquinone oxidoreductase chain 2 OS=Gallus gallus GN=MT-ND2 PE=3 SV=1	9031.ENSGALP00000034613	NADH-ubiquinone oxidoreductase chain 2 (EC 1.6.5.3)(NADH dehydrogenase subunit 2); Core subu [...] 	COG1007	KOG4668	_	_
ENSGALG00000043771	7.736412655	25.19833337	-1.702300477	1.22E-62	6.50E-61	down	yes	7.827651052	7.423067323	7.958519591	25.90303944	25.50842941	24.18353127	1	1110497	1128266	-	DENND6B	protein_coding	GO:0043547|positive regulation of GTPase activity	GO:0055037|recycling endosome	GO:0017112|Rab guanyl-nucleotide exchange factor activity	--	--	1629	XP_025008733.1	XP_025008733.1 protein DENND6B isoform X3 [Gallus gallus]	sp|Q9D9V7|DEN6B_MOUSE	sp|Q9D9V7|DEN6B_MOUSE Protein DENND6B OS=Mus musculus GN=Dennd6b PE=2 SV=3	9031.ENSGALP00000022327	"family with sequence similarity 116, member B"	_	KOG2432	_	PF08616.7|SPA|Stabilization of polarity axis|ENSGALT00000050431|m.152:223-326;PF02141.18|DENN|DENN (AEX-3) domain|ENSGALT00000050431|m.152:136-307;PF09794.6|Avl9|Transport protein Avl9|ENSGALT00000050431|m.152:31-166
ENSGALG00000043772	1.058369169	2.294018381	-1.108741978	2.06E-06	6.33E-06	down	yes	0.787639891	1.110573562	1.276894055	2.051095278	2.516031791	2.314928073	27	2264729	2273025	+	ENSGALG00000043772	protein_coding	--	--	--	--	--	2609	XP_004948510.1	XP_004948510.1 von Willebrand factor A domain-containing protein 5A isoform X1 [Gallus gallus]	sp|O00534|VMA5A_HUMAN	sp|O00534|VMA5A_HUMAN von Willebrand factor A domain-containing protein 5A OS=Homo sapiens GN=VWA5A PE=2 SV=2	9031.ENSGALP00000000252	von Willebrand factor A domain containing 5A	COG2304	_	_	PF08487.7|VIT|Vault protein inter-alpha-trypsin domain|ENSGALT00000073014|m.8445:41-150;PF13768.3|VWA_3|von Willebrand factor type A domain|ENSGALT00000073014|m.8445:292-435
ENSGALG00000043806	2.190400279	0.989227494	1.138880913	4.32E-29	6.42E-28	up	yes	2.231218757	2.16789528	2.172086802	0.972788944	0.964203303	1.030690234	15	5158427	5211083	-	DNAH10	protein_coding	GO:0007018|microtubule-based movement	GO:0005737|cytoplasm; GO:0005874|microtubule; GO:0005929|cilium; GO:0030286|dynein complex	"GO:0005524|ATP binding; GO:0008569|ATP-dependent microtubule motor activity, minus-end-directed; GO:0045503|dynein light chain binding; GO:0045505|dynein intermediate chain binding; GO:0051959|dynein light intermediate chain binding"	ko:K10408|DNAH	ko05016|Huntington's disease	13185	XP_015130844.1	"XP_015130844.1 dynein heavy chain 10, axonemal [Gallus gallus]"	sp|Q8IVF4|DYH10_HUMAN	"sp|Q8IVF4|DYH10_HUMAN Dynein heavy chain 10, axonemal OS=Homo sapiens GN=DNAH10 PE=1 SV=4"	9031.ENSGALP00000005014	"dynein, axonemal, heavy chain 10"	COG5245	KOG3595	_	"PF03028.12|Dynein_heavy|Dynein heavy chain and region D6 of dynein motor|ENSGALT00000056061|m.10459:3690-4391;PF08393.10|DHC_N2|Dynein heavy chain, N-terminal region 2|ENSGALT00000056061|m.10459:1180-1584;PF08385.9|DHC_N1|Dynein heavy chain, N-terminal region 1|ENSGALT00000056061|m.10459:179-475;PF08385.9|DHC_N1|Dynein heavy chain, N-terminal region 1|ENSGALT00000056061|m.10459:475-686;PF12774.4|AAA_6|Hydrolytic ATP binding site of dynein motor region D1|ENSGALT00000056061|m.10459:1719-1949;PF12781.4|AAA_9|ATP-binding dynein motor region D5|ENSGALT00000056061|m.10459:3326-3550;PF12780.4|AAA_8|P-loop containing dynein motor region D4|ENSGALT00000056061|m.10459:2689-2956;PF12775.4|AAA_7|P-loop containing dynein motor region D3|ENSGALT00000056061|m.10459:2348-2609;PF12777.4|MT|Microtubule-binding stalk of dynein motor|ENSGALT00000056061|m.10459:2969-3302;PF07728.11|AAA_5|AAA domain (dynein-related subfamily)|ENSGALT00000056061|m.10459:2035-2169;PF07728.11|AAA_5|AAA domain (dynein-related subfamily)|ENSGALT00000056061|m.10459:2375-2512"
ENSGALG00000043826	35.22663631	15.1810262	1.21385688	3.25E-38	7.59E-37	up	yes	38.77268821	33.57417854	33.33304218	13.22240752	17.01872322	15.30194786	6	5877972	5897241	-	ANXA11	protein_coding	GO:0032506|cytokinetic process	GO:0005635|nuclear envelope; GO:0005654|nucleoplasm; GO:0005819|spindle; GO:0030496|midbody; GO:0042470|melanosome	GO:0005509|calcium ion binding; GO:0005544|calcium-dependent phospholipid binding; GO:0044548|S100 protein binding	ko:K17095|ANXA7_11	--	2578	NP_001012921.2	NP_001012921.2 annexin A11 [Gallus gallus]	sp|P27214|ANX11_BOVIN	sp|P27214|ANX11_BOVIN Annexin A11 OS=Bos taurus GN=ANXA11 PE=1 SV=1	9031.ENSGALP00000040310	annexin A11 	_	KOG0819	_	PF00191.17|Annexin|Annexin|ENSGALT00000098459|m.4362:191-255;PF00191.17|Annexin|Annexin|ENSGALT00000098459|m.4362:263-328;PF00191.17|Annexin|Annexin|ENSGALT00000098459|m.4362:347-412;PF00191.17|Annexin|Annexin|ENSGALT00000098459|m.4362:422-487
ENSGALG00000043885	0.293139401	1.180342201	-1.973323095	0.000124721	0.0003014	down	yes	0.303071178	0.444424102	0.131922923	1.139996745	1.095895252	1.305134605	25	3891408	3894593	+	CFAP45	protein_coding	--	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005929|cilium	--	--	--	1217	XP_015154162.2	XP_015154162.2 cilia- and flagella-associated protein 45 [Gallus gallus]	sp|Q9UL16|CFA45_HUMAN	sp|Q9UL16|CFA45_HUMAN Cilia- and flagella-associated protein 45 OS=Homo sapiens GN=CFAP45 PE=1 SV=2	_	_	_	_	_	PF13868.3|TPH|Trichohyalin-plectin-homology domain|ENSGALT00000090075|m.7360:15-363
ENSGALG00000043900	0.102786159	0.883264943	-2.985498111	4.64E-05	0.000119584	down	yes	0.196242418	0	0.112116059	0.959610987	0.795534878	0.894648963	16	1459700	1461203	-	ENSGALG00000043900	protein_coding	--	GO:0005576|extracellular region; GO:0016020|membrane	GO:0005044|scavenger receptor activity	--	--	1074	XP_025011581.1	XP_025011581.1 scavenger receptor cysteine-rich type 1 protein M130-like isoform X1 [Gallus gallus]	sp|P30205|WC11_BOVIN	sp|P30205|WC11_BOVIN Antigen WC1.1 OS=Bos taurus PE=2 SV=1	9031.ENSGALP00000002137	annotation not avaliable	_	_	NOG83796	PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000084469|m.11291:13-110;PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000084469|m.11291:116-212;PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000084469|m.11291:218-315
ENSGALG00000044098	2.249792487	5.562722076	-1.302191907	9.03E-16	6.38E-15	down	yes	2.437145657	2.251515814	2.060715989	5.665378566	5.272435632	5.750352029	2	560400	565502	-	ENSGALG00000044098	protein_coding	--	--	--	ko:K09228|KRAB	--	2162	XP_418475.4	XP_418475.4 zinc finger protein 777 isoform X1 [Gallus gallus]	_	_	_	_	_	_	_	PF01352.24|KRAB|KRAB box|ENSGALT00000084052|m.14428:64-104
ENSGALG00000044138	0.914498743	0.244171295	1.862870251	0.0004598	0.001020905	up	yes	0.627690009	0.92044572	1.195360501	0.078701487	0.303415572	0.350396826	1	93224989	93234633	+	GPA33	protein_coding	--	GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0070062|extracellular exosome	--	ko:K06790|GPA33	--	1511	XP_416656.1	XP_416656.1 cell surface A33 antigen [Gallus gallus]	sp|Q9JKA5|GPA33_MOUSE	sp|Q9JKA5|GPA33_MOUSE Cell surface A33 antigen OS=Mus musculus GN=Gpa33 PE=2 SV=2	9031.ENSGALP00000024874	glycoprotein A33 (transmembrane)	_	_	NOG44728	PF07686.14|V-set|Immunoglobulin V-set domain|ENSGALT00000083307|m.2883:26-131;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000083307|m.2883:26-120;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000083307|m.2883:147-211;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000083307|m.2883:146-208;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000083307|m.2883:145-221;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000083307|m.2883:147-221
ENSGALG00000044155	0.450266558	1.329008787	-1.540623898	1.42E-05	3.92E-05	down	yes	0.463473021	0.446012204	0.44131445	1.470947658	1.168549523	1.347529179	1	47922457	47927316	-	TMEM140	protein_coding	--	GO:0016021|integral component of membrane	--	--	--	1819	XP_416181.2	XP_416181.2 transmembrane protein 140 [Gallus gallus]	sp|Q9NV12|TM140_HUMAN	sp|Q9NV12|TM140_HUMAN Transmembrane protein 140 OS=Homo sapiens GN=TMEM140 PE=1 SV=2	9031.ENSGALP00000019135	transmembrane protein 140	_	_	NOG47402	PF14985.3|TM140|TM140 protein family|ENSGALT00000090133|m.1149:34-199
ENSGALG00000044241	4.160830991	1.453899014	1.51051882	2.32E-11	1.15E-10	up	yes	4.145277989	3.939861102	4.397353883	1.051042454	1.49371409	1.816940498	11	585151	586866	+	ENSGALG00000044241	protein_coding	--	--	--	--	--	1716	XP_015128105.1	XP_015128105.1 endogenous retrovirus group K member 8 Gag polyprotein [Gallus gallus]	_	_	_	_	_	_	_	PF00607.17|Gag_p24|gag gene protein p24 (core nucleocapsid protein)|ENSGALT00000088663|m.6170:231-411;PF00098.20|zf-CCHC|Zinc knuckle|ENSGALT00000088663|m.6170:489-504
ENSGALG00000044251	0.793834559	2.198667507	-1.458205743	4.18E-06	1.23E-05	down	yes	0.77033756	0.818977644	0.792188472	2.361552782	2.28499267	1.949457067	5	16101556	16106288	-	RASSF7	protein_coding	GO:0007165|signal transduction; GO:0034334|adherens junction maintenance	--	--	ko:K09855|RASSF7_8	--	1368	XP_015142211.1	XP_015142211.1 ras association domain-containing protein 8 isoform X2 [Gallus gallus]	sp|Q8CJ96|RASF8_MOUSE	sp|Q8CJ96|RASF8_MOUSE Ras association domain-containing protein 8 OS=Mus musculus GN=Rassf8 PE=2 SV=1	9031.ENSGALP00000011120	Ras association (RalGDS/AF-6) domain family 7	_	KOG1574	_	PF00788.20|RA|Ras association (RalGDS/AF-6) domain|ENSGALT00000011134|m.2656:2-80
ENSGALG00000044279	0.503584896	0.099758518	2.226269868	1.31E-06	4.12E-06	up	yes	0.676861817	0.381750517	0.452142353	0.035252356	0.074131304	0.189891895	3	109820943	109830241	+	TDRD6	protein_coding	GO:0007275|multicellular organism development; GO:0007283|spermatogenesis; GO:0030154|cell differentiation	GO:0005737|cytoplasm; GO:0033391|chromatoid body	--	ko:K18405|TDRD1_4_6_7	--	5060	XP_025004999.1	XP_025004999.1 tudor domain-containing protein 6 [Gallus gallus]	sp|O60522|TDRD6_HUMAN	sp|O60522|TDRD6_HUMAN Tudor domain-containing protein 6 OS=Homo sapiens GN=TDRD6 PE=2 SV=2	_	_	_	_	_	PF00567.21|TUDOR|Tudor domain|ENSGALT00000084070|m.13370:187-300;PF00567.21|TUDOR|Tudor domain|ENSGALT00000084070|m.13370:397-515;PF00567.21|TUDOR|Tudor domain|ENSGALT00000084070|m.13370:708-823;PF00567.21|TUDOR|Tudor domain|ENSGALT00000084070|m.13370:924-1041;PF06003.9|SMN|Survival motor neuron protein (SMN)|ENSGALT00000084070|m.13370:974-1022
ENSGALG00000044313	1.770630076	0.673460674	1.381457596	1.58E-07	5.55E-07	up	yes	1.764688032	1.659814053	1.887388142	0.885045608	0.690877892	0.444458521	5	16056642	16063897	-	ENSGALG00000044313	protein_coding	--	--	--	--	--	2851	XP_015142206.2	XP_015142206.2 malignant fibrous histiocytoma-amplified sequence 1 homolog isoform X2 [Gallus gallus]	_	_	_	_	_	_	_	"PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000050550|m.2650:33-88;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000050550|m.2650:77-135;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000050550|m.2650:101-158;PF08477.10|Roc|Ras of Complex, Roc, domain of DAPkinase|ENSGALT00000050550|m.2650:239-355;PF16095.2|COR|C-terminal of Roc, COR, domain|ENSGALT00000050550|m.2650:491-720;PF00025.18|Arf|ADP-ribosylation factor family|ENSGALT00000050550|m.2650:232-318;PF00071.19|Ras|Ras family|ENSGALT00000050550|m.2650:239-373"
ENSGALG00000044391	0.489093133	2.139926133	-2.106906134	4.99E-11	2.42E-10	down	yes	0.357026013	0.588986512	0.521266874	2.29420092	1.988601639	2.136975839	1	99412225	99420340	+	RBM11	protein_coding	"GO:0000381|regulation of alternative mRNA splicing, via spliceosome; GO:0006397|mRNA processing; GO:0007275|multicellular organism development; GO:0008380|RNA splicing; GO:0030154|cell differentiation; GO:0034599|cellular response to oxidative stress"	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0016607|nuclear speck	GO:0008266|poly(U) RNA binding; GO:0042803|protein homodimerization activity	--	--	1771	XP_416676.3	XP_416676.3 splicing regulator RBM11 [Gallus gallus]	sp|P57052|RBM11_HUMAN	sp|P57052|RBM11_HUMAN Splicing regulator RBM11 OS=Homo sapiens GN=RBM11 PE=1 SV=1	_	_	_	_	_	"PF00076.19|RRM_1|RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)|ENSGALT00000083517|m.2966:14-83"
ENSGALG00000044404	15.18442273	7.270697629	1.061393265	1.36E-22	1.49E-21	up	yes	15.72309586	15.09643607	14.73373626	7.568785801	7.242493287	7.000813798	20	3812263	3821985	+	ENSGALG00000044404	protein_coding	GO:0008283|cell population proliferation; GO:0051301|cell division; GO:0051310|metaphase plate congression; GO:0070372|regulation of ERK1 and ERK2 cascade	GO:0005737|cytoplasm; GO:0097431|mitotic spindle pole	--	"ko:K16805|FAM83D,CHICA"	--	1689	XP_422895.3	XP_422895.3 protein FAM83D-B [Gallus gallus]	sp|Q5XGY0|F83DA_XENLA	sp|Q5XGY0|F83DA_XENLA Protein FAM83D-A OS=Xenopus laevis GN=fam83d-a PE=2 SV=1	9031.ENSGALP00000004885	"family with sequence similarity 83, member D"	_	_	NOG46243	PF07894.9|DUF1669|Protein of unknown function (DUF1669)|ENSGALT00000085976|m.2951:44-304;PF13091.3|PLDc_2|PLD-like domain|ENSGALT00000085976|m.2951:162-293
ENSGALG00000044466	3.404524839	10.67999302	-1.646504177	4.67E-39	1.11E-37	down	yes	3.23315709	3.607364154	3.373053273	11.13919401	10.65584843	10.24493661	11	2644433	2658115	+	ENSGALG00000044466	protein_coding	--	--	--	ko:K08846|RIPK2	ko04621|NOD-like receptor signaling pathway; ko04722|Neurotrophin signaling pathway; ko05131|Shigellosis; ko05152|Tuberculosis	2249	XP_004944206.1	XP_004944206.1 receptor-interacting serine/threonine-protein kinase 2 isoform X1 [Gallus gallus]	_	_	9031.ENSGALP00000033747	similar to Hypothetical protein CBG04537	_	KOG0192	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000091903|m.6429:3-186;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000091903|m.6429:2-187;PF00619.18|CARD|Caspase recruitment domain|ENSGALT00000091903|m.6429:328-399
ENSGALG00000044478	0.153256368	0.317658424	-1.005053355	0.018668341	0.031194796	down	yes	0.114636468	0.10697471	0.238157927	0.321442233	0.383314751	0.248218286	1	41786239	41885102	+	ENSGALG00000044478	protein_coding	--	--	--	--	--	5056	XP_025010326.1	XP_025010326.1 leucine-rich repeat and IQ domain-containing protein 1 isoform X1 [Gallus gallus]	sp|Q96JM4|LRIQ1_HUMAN	sp|Q96JM4|LRIQ1_HUMAN Leucine-rich repeat and IQ domain-containing protein 1 OS=Homo sapiens GN=LRRIQ1 PE=2 SV=3	9031.ENSGALP00000018114	leucine-rich repeats and IQ motif containing 1	_	KOG0531	_	PF12799.4|LRR_4|Leucine Rich repeats (2 copies)|ENSGALT00000094848|m.1006:746-783;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000094848|m.1006:294-311;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000094848|m.1006:1140-1158;PF00612.24|IQ|IQ calmodulin-binding motif|ENSGALT00000094848|m.1006:1177-1196
ENSGALG00000044525	5.913585508	12.48008859	-1.076241111	2.11E-11	1.06E-10	down	yes	6.929485672	4.915746962	5.895523889	11.086145	12.70635446	13.64776632	3	30373847	30381379	+	NFKBIE	protein_coding	GO:0042942|D-serine transport; GO:0042994|cytoplasmic sequestering of transcription factor	GO:0001650|fibrillar center; GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005794|Golgi apparatus; GO:0005829|cytosol; GO:0048471|perinuclear region of cytoplasm	--	ko:K05872|NFKBIE	ko04658|Th1 and Th2 cell differentiation; ko04659|Th17 cell differentiation; ko04660|T cell receptor signaling pathway; ko04662|B cell receptor signaling pathway; ko04722|Neurotrophin signaling pathway; ko04920|Adipocytokine signaling pathway; ko05169|Epstein-Barr virus infection	1092	XP_419490.3	XP_419490.3 NF-kappa-B inhibitor epsilon [Gallus gallus]	sp|O00221|IKBE_HUMAN	sp|O00221|IKBE_HUMAN NF-kappa-B inhibitor epsilon OS=Homo sapiens GN=NFKBIE PE=1 SV=3	_	_	_	_	_	PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000107921|m.11390:153-250;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000107921|m.11390:151-179;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000107921|m.11390:181-204;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000107921|m.11390:151-201
ENSGALG00000044581	9.873846284	33.79838292	-1.774236534	1.16E-61	6.03E-60	down	yes	11.29094767	10.16200831	8.168582873	33.62825142	34.68463432	33.08226303	21	5494887	5501078	-	MIIP	protein_coding	GO:0010972|negative regulation of G2/M transition of mitotic cell cycle; GO:0030336|negative regulation of cell migration	--	--	--	--	1764	XP_015152690.1	XP_015152690.1 migration and invasion-inhibitory protein [Gallus gallus]	sp|Q5JXC2|MIIP_HUMAN	sp|Q5JXC2|MIIP_HUMAN Migration and invasion-inhibitory protein OS=Homo sapiens GN=MIIP PE=1 SV=3	_	_	_	_	_	PF15734.2|MIIP|Migration and invasion-inhibitory|ENSGALT00000090263|m.4267:119-429
ENSGALG00000044610	0.243179536	0.64999282	-1.38228953	0.005923786	0.010936151	down	yes	0.068223249	0.366823198	0.294492161	0.607335217	0.809461366	0.533181878	12	11055336	11066489	+	CFAP100	protein_coding	GO:0003341|cilium movement; GO:0036159|inner dynein arm assembly; GO:2000574|regulation of microtubule motor activity	GO:0005737|cytoplasm; GO:0031514|motile cilium; GO:0097545|axonemal outer doublet	GO:0070840|dynein complex binding	--	--	2317	XP_425162.4	XP_425162.4 cilia- and flagella-associated protein 100 isoform X1 [Gallus gallus]	sp|Q494V2|CP100_HUMAN	sp|Q494V2|CP100_HUMAN Cilia- and flagella-associated protein 100 OS=Homo sapiens GN=CFAP100 PE=2 SV=1	9031.ENSGALP00000010107	coiled-coil domain containing 37	_	_	NOG45507	PF13863.3|DUF4200|Domain of unknown function (DUF4200)|ENSGALT00000083572|m.7726:165-283
ENSGALG00000044642	5.961444452	17.50753313	-1.552647768	5.91E-63	3.17E-61	down	yes	5.96188682	5.592283107	6.330163428	16.70012877	18.17167142	17.6507992	1	86387245	86424407	-	SENP7	protein_coding	GO:0007188|adenylate cyclase-modulating G protein-coupled receptor signaling pathway	GO:0005634|nucleus; GO:0005886|plasma membrane	GO:0004930|G protein-coupled receptor activity; GO:0008234|cysteine-type peptidase activity	ko:K08596|SENP7	--	3164	XP_004938322.1	XP_004938322.1 sentrin-specific protease 7 isoform X1 [Gallus gallus]	sp|A7MBJ2|SENP7_BOVIN	sp|A7MBJ2|SENP7_BOVIN Sentrin-specific protease 7 OS=Bos taurus GN=SENP7 PE=2 SV=1	9031.ENSGALP00000036118	SUMO1/sentrin specific peptidase 7	COG5160	KOG0779	_	"PF02902.16|Peptidase_C48|Ulp1 protease family, C-terminal catalytic domain|ENSGALT00000085681|m.2754:758-1024"
ENSGALG00000044739	3.255788821	1.05620435	1.614947531	3.56E-12	1.90E-11	up	yes	3.684691546	2.971780946	3.11089397	0.958643117	1.044385461	1.16558447	1	196312459	196314174	-	ENSGALG00000044739	protein_coding	--	--	--	--	--	1716	XP_015128105.1	XP_015128105.1 endogenous retrovirus group K member 8 Gag polyprotein [Gallus gallus]	_	_	_	_	_	_	_	PF00607.17|Gag_p24|gag gene protein p24 (core nucleocapsid protein)|ENSGALT00000086546|m.4912:231-412;PF00098.20|zf-CCHC|Zinc knuckle|ENSGALT00000086546|m.4912:489-504
ENSGALG00000044816	3.192764129	0.866935663	1.868774646	2.39E-11	1.19E-10	up	yes	4.107240794	2.821522359	2.649529235	0.862934535	0.980492922	0.757379532	4	18648264	18664987	-	ENSGALG00000044816	protein_coding	--	--	--	--	--	1424	XP_021261910.1	XP_021261910.1 fragile X mental retardation 1 neighbor protein [Numida meleagris]	_	_	_	_	_	_	_	_
ENSGALG00000044851	1.546939065	3.577752035	-1.204367701	3.74E-10	1.68E-09	down	yes	1.624915776	1.124457655	1.891443763	3.763400007	3.429864258	3.539991838	KZ626836.1	255656	259209	-	ENSGALG00000044851	protein_coding	--	--	--	--	--	2886	XP_004950828.1	XP_004950828.1 inter-alpha-trypsin inhibitor heavy chain H6 isoform X1 [Gallus gallus]	_	_	9986.ENSOCUP00000003844	inter-alpha (globulin) inhibitor H5-like	COG2304	KOG2353	_	PF06668.9|ITI_HC_C|Inter-alpha-trypsin inhibitor heavy chain C-terminus|ENSGALT00000084133|m.9755:589-762;PF13768.3|VWA_3|von Willebrand factor type A domain|ENSGALT00000084133|m.9755:20-100;PF13768.3|VWA_3|von Willebrand factor type A domain|ENSGALT00000084133|m.9755:158-243;PF00092.25|VWA|von Willebrand factor type A domain|ENSGALT00000084133|m.9755:21-68;PF13519.3|VWA_2|von Willebrand factor type A domain|ENSGALT00000084133|m.9755:22-92
ENSGALG00000044874	5.026923324	1.625951412	1.622412868	5.80E-11	2.80E-10	up	yes	4.683652365	5.682548327	4.714569279	1.698827803	1.477483515	1.701542919	2	3966061	3968522	+	ENSGALG00000044874	protein_coding	GO:0001701|in utero embryonic development; GO:0006954|inflammatory response; GO:0006955|immune response; GO:0007420|brain development; GO:0010942|positive regulation of cell death; GO:0032496|response to lipopolysaccharide; GO:0042127|regulation of cell population proliferation; GO:0042981|regulation of apoptotic process; GO:0097190|apoptotic signaling pathway	GO:0005634|nucleus; GO:0005641|nuclear envelope lumen; GO:0005887|integral component of plasma membrane; GO:0016020|membrane; GO:0030027|lamellipodium; GO:0032589|neuron projection membrane; GO:0044298|cell body membrane	GO:0005031|tumor necrosis factor-activated receptor activity; GO:0005166|neurotrophin p75 receptor binding	--	--	945	XP_418509.4	XP_418509.4 tumor necrosis factor receptor superfamily member 16-like [Gallus gallus]	sp|Q8K5A9|NRADD_RAT	sp|Q8K5A9|NRADD_RAT Death domain-containing membrane protein NRADD OS=Rattus norvegicus GN=Nradd PE=1 SV=2	8364.ENSXETP00000051462	Ngfr-prov protein	_	_	NOG250876	PF00531.19|Death|Death domain|ENSGALT00000084155|m.14604:231-304
ENSGALG00000045092	1.519707629	3.494079434	-1.195779541	1.72E-09	7.30E-09	down	yes	1.411585759	1.534619445	1.612917684	3.771685438	3.513294966	3.197257898	Z	79040637	79049732	-	CCDC112	protein_coding	--	--	--	--	--	1523	XP_015136310.1	XP_015136310.1 coiled-coil domain-containing protein 112 [Gallus gallus]	sp|Q4R8R3|CC112_MACFA	sp|Q4R8R3|CC112_MACFA Coiled-coil domain-containing protein 112 OS=Macaca fascicularis GN=CCDC112 PE=2 SV=1	9031.ENSGALP00000036717	"PREDICTED: Gallus gallus similar to mutated in bladder cancer 1 (LOC770644), mRNA"	_	_	NOG68598	_
ENSGALG00000045125	2.802592311	0.562589282	2.296327876	1.70E-19	1.55E-18	up	yes	2.972886712	2.781586965	2.653303257	0.358840118	0.693175377	0.635752352	9	13054465	13058403	+	GP5	protein_coding	--	--	--	"ko:K06260|GP5,CD42d"	ko04512|ECM-receptor interaction; ko04611|Platelet activation; ko04640|Hematopoietic cell lineage	2375	XP_004943385.1	XP_004943385.1 platelet glycoprotein V [Gallus gallus]	_	_	_	_	_	_	_	PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000062603|m.8842:51-109;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000062603|m.8842:97-157;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000062603|m.8842:146-205;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000062603|m.8842:194-253;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000062603|m.8842:218-277;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000062603|m.8842:242-301;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000062603|m.8842:267-324;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000062603|m.8842:289-350;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000062603|m.8842:314-370;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000062603|m.8842:363-421;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000062603|m.8842:50-155;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000062603|m.8842:134-253;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000062603|m.8842:207-339;PF13306.3|LRR_5|Leucine rich repeats (6 copies)|ENSGALT00000062603|m.8842:303-415
ENSGALG00000045238	3.547152509	1.705522497	1.052074784	4.74E-07	1.57E-06	up	yes	3.434597634	3.157805516	4.049054375	1.579010495	1.49852018	2.039036817	19	39927	42416	-	ENSGALG00000045238	protein_coding	--	--	GO:0004126|cytidine deaminase activity; GO:0047844|deoxycytidine deaminase activity	--	--	1933	XP_024997907.1	XP_024997907.1 fibrinogen-like protein 1-like protein [Gallus gallus]	sp|O93526|FGL1L_CHICK	sp|O93526|FGL1L_CHICK Fibrinogen-like protein 1-like protein OS=Gallus gallus PE=1 SV=2	9031.ENSGALP00000034569	similar to cytidine deaminase	_	KOG2579	_	"PF00147.15|Fibrinogen_C|Fibrinogen beta and gamma chains, C-terminal globular domain|ENSGALT00000083797|m.13388:104-283"
ENSGALG00000045251	2.679686508	5.557006282	-1.04946368	1.54E-15	1.07E-14	down	yes	2.419488785	2.936908006	2.682662732	6.148138716	5.050300127	5.472580003	24	5522180	5531915	+	ENSGALG00000045251	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006357|regulation of transcription by RNA polymerase II; GO:0006954|inflammatory response"	GO:0005634|nucleus; GO:0016607|nuclear speck; GO:0036464|cytoplasmic ribonucleoprotein granule	GO:0003712|transcription coregulator activity	--	--	3920	XP_425809.3	XP_425809.3 uncharacterized protein LOC428250 [Gallus gallus]	sp|Q9EST8|IKBZ_MOUSE	sp|Q9EST8|IKBZ_MOUSE NF-kappa-B inhibitor zeta OS=Mus musculus GN=Nfkbiz PE=1 SV=1	_	_	_	_	_	"PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000089846|m.6406:405-456;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000089846|m.6406:405-434;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000089846|m.6406:437-457;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000089846|m.6406:420-484;PF09310.7|PD-C2-AF1|POU domain, class 2, associating factor 1|ENSGALT00000089846|m.6406:85-112"
ENSGALG00000045288	6.56432022	2.066502542	1.662686091	0.000469899	0.001041605	up	yes	7.205619023	5.283166126	7.20417551	2.286883581	0.979617371	2.933006673	21	4889771	4890492	-	CAMK2N1	protein_coding	GO:0008285|negative regulation of cell population proliferation; GO:0010628|positive regulation of gene expression; GO:0045786|negative regulation of cell cycle; GO:0045861|negative regulation of proteolysis; GO:0070373|negative regulation of ERK1 and ERK2 cascade; GO:1904030|negative regulation of cyclin-dependent protein kinase activity	GO:0005622|intracellular; GO:0014069|postsynaptic density; GO:0030054|cell junction; GO:0043005|neuron projection; GO:0045211|postsynaptic membrane	GO:0008427|calcium-dependent protein kinase inhibitor activity; GO:0019901|protein kinase binding	--	--	234	XP_015738311.1	XP_015738311.1 PREDICTED: calcium/calmodulin-dependent protein kinase II inhibitor 1 [Coturnix japonica]	sp|A7MBG3|CK2N1_BOVIN	sp|A7MBG3|CK2N1_BOVIN Calcium/calmodulin-dependent protein kinase II inhibitor 1 OS=Bos taurus GN=CAMK2N1 PE=3 SV=1	_	_	_	_	_	_
ENSGALG00000045350	0.716759798	1.445049335	-1.001517549	4.58E-05	0.000118219	down	yes	0.647637086	0.718359907	0.7842824	1.305486436	1.3857728	1.64388877	4	16632507	16671022	+	ENSGALG00000045350	protein_coding	--	--	--	--	--	3108	XP_004940901.1	XP_004940901.1 acrosomal protein KIAA1210 homolog isoform X1 [Gallus gallus]	sp|Q6NV74|K121L_HUMAN	sp|Q6NV74|K121L_HUMAN Uncharacterized protein KIAA1211-like OS=Homo sapiens GN=KIAA1211L PE=1 SV=3	9031.ENSGALP00000014371	annotation not avaliable	_	_	NOG134798	PF15262.3|DUF4592|Domain of unknown function (DUF4592)|ENSGALT00000099838|m.16638:127-258
ENSGALG00000045478	2.49715694	5.488097404	-1.132880159	5.05E-18	4.17E-17	down	yes	2.424857646	2.348180024	2.718433149	5.472634862	5.736039256	5.255618094	5	50363371	50382143	-	ENSGALG00000045478	protein_coding	--	--	--	--	--	3455	XP_430056.4	XP_430056.4 exocyst complex component 3-like protein [Gallus gallus]	_	_	9031.ENSGALP00000018648	hypothetical LOC423478	_	_	NOG292787	PF06046.10|Sec6|Exocyst complex component Sec6|ENSGALT00000088698|m.3900:350-625
ENSGALG00000045520	8.919645257	3.408774071	1.385123778	2.20E-11	1.10E-10	up	yes	9.744719253	8.318631208	8.695585311	3.82254957	3.165786411	3.237986231	13	11295210	11299437	+	ENSGALG00000045520	protein_coding	GO:0048545|response to steroid hormone	GO:0005615|extracellular space; GO:0005783|endoplasmic reticulum; GO:0032991|protein-containing complex	GO:0004867|serine-type endopeptidase inhibitor activity; GO:0019863|IgE binding; GO:0019864|IgG binding; GO:0030246|carbohydrate binding	--	--	757	XP_004944966.1	"XP_004944966.1 double-headed protease inhibitor, submandibular gland [Gallus gallus]"	sp|P01005|IOVO_CHICK	sp|P01005|IOVO_CHICK Ovomucoid OS=Gallus gallus PE=1 SV=1	59729.ENSTGUP00000000581	similar to ovomucoid	_	KOG3649	_	PF00050.18|Kazal_1|Kazal-type serine protease inhibitor domain|ENSGALT00000089362|m.8761:50-97;PF00050.18|Kazal_1|Kazal-type serine protease inhibitor domain|ENSGALT00000089362|m.8761:108-150;PF00050.18|Kazal_1|Kazal-type serine protease inhibitor domain|ENSGALT00000089362|m.8761:160-210;PF07648.12|Kazal_2|Kazal-type serine protease inhibitor domain|ENSGALT00000089362|m.8761:58-97;PF07648.12|Kazal_2|Kazal-type serine protease inhibitor domain|ENSGALT00000089362|m.8761:119-143;PF07648.12|Kazal_2|Kazal-type serine protease inhibitor domain|ENSGALT00000089362|m.8761:170-210
ENSGALG00000045529	5.037696802	2.30697458	1.123383039	0.00014372	0.00034442	up	yes	5.02960396	3.424302135	6.659184311	2.25223383	1.705019985	2.963669925	5	567699	570024	+	RAB15	protein_coding	GO:0006904|vesicle docking involved in exocytosis; GO:0007269|neurotransmitter secretion; GO:0009306|protein secretion; GO:0017157|regulation of exocytosis; GO:1903307|positive regulation of regulated secretory pathway	GO:0005737|cytoplasm; GO:0005886|plasma membrane; GO:0005929|cilium; GO:0010008|endosome membrane; GO:0016020|membrane; GO:0048471|perinuclear region of cytoplasm; GO:0070062|extracellular exosome; GO:0098793|presynapse	GO:0003924|GTPase activity; GO:0005525|GTP binding	ko:K07908|RAB15	--	880	XP_025006966.1	XP_025006966.1 ras-related protein Rab-15 isoform X1 [Gallus gallus]	sp|P35289|RAB15_RAT	sp|P35289|RAB15_RAT Ras-related protein Rab-15 OS=Rattus norvegicus GN=Rab15 PE=2 SV=1	_	_	_	_	_	"PF00071.19|Ras|Ras family|ENSGALT00000087153|m.2143:25-184;PF08477.10|Roc|Ras of Complex, Roc, domain of DAPkinase|ENSGALT00000087153|m.2143:24-139;PF00025.18|Arf|ADP-ribosylation factor family|ENSGALT00000087153|m.2143:18-181;PF04670.9|Gtr1_RagA|Gtr1/RagA G protein conserved region|ENSGALT00000087153|m.2143:24-145;PF01926.20|MMR_HSR1|50S ribosome-binding GTPase|ENSGALT00000087153|m.2143:25-117"
ENSGALG00000045581	3.801661692	1.400431269	1.434283712	1.39E-09	5.96E-09	up	yes	3.341715452	4.232074979	3.831194645	1.231586673	1.788881385	1.180825749	2	505017	507099	+	ENSGALG00000045581	protein_coding	GO:0070232|regulation of T cell apoptotic process	GO:0005739|mitochondrion; GO:0005783|endoplasmic reticulum; GO:0005794|Golgi apparatus; GO:0005829|cytosol	GO:0005525|GTP binding	--	--	1561	XP_418473.2	XP_418473.2 GTPase IMAP family member 1 [Gallus gallus]	sp|Q75N62|GIMA8_MOUSE	sp|Q75N62|GIMA8_MOUSE GTPase IMAP family member 8 OS=Mus musculus GN=Gimap8 PE=1 SV=1	9031.ENSGALP00000014480	"GTPase, IMAP family member 1"	_	_	NOG70913	PF04548.13|AIG1|AIG1 family|ENSGALT00000088857|m.14418:193-380;PF01926.20|MMR_HSR1|50S ribosome-binding GTPase|ENSGALT00000088857|m.14418:194-317
ENSGALG00000045608	0.421441675	0.937780402	-1.13538729	0.000125617	0.000303445	down	yes	0.484347059	0.355123684	0.424854282	1.076555223	0.737206103	0.999579879	22	3710877	3715597	+	ENSGALG00000045608	protein_coding	--	--	--	--	--	2976	XP_024998603.1	XP_024998603.1 protein FAM178B isoform X1 [Gallus gallus]	_	_	9031.ENSGALP00000005499	"family with sequence similarity 178, member B"	_	_	NOG284955	"PF14816.3|FAM178|Family of unknown function, FAM178|ENSGALT00000093947|m.4870:101-387;PF14816.3|FAM178|Family of unknown function, FAM178|ENSGALT00000093947|m.4871:131-167"
ENSGALG00000045636	0.112275625	0.501433862	-2.064410842	9.94E-05	0.000243851	down	yes	0.12893415	0.126046174	0.081846552	0.444568178	0.475934526	0.583798881	Z	7621689	7637215	-	ENSGALG00000045636	protein_coding	--	--	--	--	--	2452	XP_004937158.1	XP_004937158.1 uncharacterized protein LOC427400 isoform X2 [Gallus gallus]	_	_	9031.ENSGALP00000009320	hypothetical LOC427400	_	_	NOG121097	PF00652.19|Ricin_B_lectin|Ricin-type beta-trefoil lectin domain|ENSGALT00000084952|m.10405:25-131;PF15048.3|OSTbeta|Organic solute transporter subunit beta protein|ENSGALT00000084952|m.10405:246-333
ENSGALG00000045684	7.253192745	1.520987849	2.246141033	1.44E-28	2.12E-27	up	yes	6.797488258	8.079529446	6.882560532	1.30225315	1.73659443	1.524115968	28	3528771	3530950	-	ENSGALG00000045684	protein_coding	--	--	--	ko:K17309|PLVAP	--	1248	XP_003643535.1	XP_003643535.1 plasmalemma vesicle-associated protein [Gallus gallus]	_	_	_	_	_	_	_	PF06637.8|PV-1|PV-1 protein (PLVAP)|ENSGALT00000086440|m.10253:15-198
ENSGALG00000045705	16.87806418	7.25322069	1.217322645	9.30E-18	7.53E-17	up	yes	16.79830593	16.43681136	17.39907526	6.750502681	7.026038013	7.983121375	24	65508	66379	+	H2AFX	protein_coding	GO:0006281|DNA repair; GO:0006310|DNA recombination; GO:0006342|chromatin silencing; GO:0006974|cellular response to DNA damage stimulus; GO:0051321|meiotic cell cycle	GO:0000786|nucleosome; GO:0000790|nuclear chromatin; GO:0005813|centrosome	GO:0003677|DNA binding; GO:0046982|protein heterodimerization activity	ko:K11251|H2A	ko05034|Alcoholism; ko05322|Systemic lupus erythematosus	872	XP_004947974.3	XP_004947974.3 histone H2A [Gallus gallus]	sp|Q7ZUY3|H2AX_DANRE	sp|Q7ZUY3|H2AX_DANRE Histone H2AX OS=Danio rerio GN=h2afx PE=2 SV=3	_	_	_	_	_	PF16211.2|Histone_H2A_C|C-terminus of histone H2A|ENSGALT00000086666|m.5966:125-158;PF00125.21|Histone|Core histone H2A/H2B/H3/H4|ENSGALT00000086666|m.5966:38-122;PF00808.20|CBFD_NFYB_HMF|Histone-like transcription factor (CBF/NF-Y) and archaeal histone|ENSGALT00000086666|m.5966:58-121
ENSGALG00000045721	16.08556591	6.859609343	1.228363338	1.06E-33	2.02E-32	up	yes	15.77713126	15.51598905	16.96357741	6.909431768	6.458738022	7.21065824	25	2626869	2630717	+	ISG20L2	protein_coding	GO:0042254|ribosome biogenesis	GO:0005730|nucleolus	GO:0000175|3'-5'-exoribonuclease activity; GO:0003723|RNA binding	ko:K18329|ISG20L2	--	2094	POI28996.1	POI28996.1 hypothetical protein CIB84_007251 [Bambusicola thoracicus]	sp|Q2YDK1|I20L2_BOVIN	sp|Q2YDK1|I20L2_BOVIN Interferon-stimulated 20 kDa exonuclease-like 2 OS=Bos taurus GN=ISG20L2 PE=2 SV=1	9031.ENSGALP00000040035	annotation not avaliable	COG0847	KOG2249	_	PF00929.21|RNase_T|Exonuclease|ENSGALT00000083319|m.6973:137-292
ENSGALG00000045816	0.7510424	3.167930844	-2.062038993	6.24E-09	2.51E-08	down	yes	0.964155336	0.848303436	0.440668427	2.955722055	3.946661082	2.601409396	24	286060	292352	-	ENSGALG00000045816	protein_coding	GO:0001656|metanephros development; GO:0001657|ureteric bud development; GO:0007156|homophilic cell adhesion via plasma membrane adhesion molecules; GO:0007411|axon guidance; GO:0007417|central nervous system development; GO:0007420|brain development; GO:0016199|axon midline choice point recognition; GO:0021510|spinal cord development; GO:0021891|olfactory bulb interneuron development; GO:0031290|retinal ganglion cell axon guidance; GO:0032870|cellular response to hormone stimulus; GO:0035385|Roundabout signaling pathway; GO:0050772|positive regulation of axonogenesis; GO:0050925|negative regulation of negative chemotaxis; GO:0051964|negative regulation of synapse assembly; GO:0061364|apoptotic process involved in luteolysis	GO:0009986|cell surface; GO:0016021|integral component of membrane; GO:0030673|axolemma; GO:0070062|extracellular exosome	GO:0008046|axon guidance receptor activity; GO:0042802|identical protein binding	ko:K06755|ROBO3	ko04360|Axon guidance	1056	XP_015153564.1	XP_015153564.1 roundabout homolog 3 isoform X1 [Gallus gallus]	sp|Q9HCK4|ROBO2_HUMAN	sp|Q9HCK4|ROBO2_HUMAN Roundabout homolog 2 OS=Homo sapiens GN=ROBO2 PE=1 SV=2	9031.ENSGALP00000001377	annotation not avaliable	_	KOG4222	_	PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000094750|m.6004:31-127;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000094750|m.6004:135-214;PF07679.13|I-set|Immunoglobulin I-set domain|ENSGALT00000094750|m.6004:225-310;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000094750|m.6004:31-114;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000094750|m.6004:137-207;PF13927.3|Ig_3|Immunoglobulin domain|ENSGALT00000094750|m.6004:230-297;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000094750|m.6004:37-122;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000094750|m.6004:138-214;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000094750|m.6004:231-305;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000094750|m.6004:37-126;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000094750|m.6004:139-221;PF13895.3|Ig_2|Immunoglobulin domain|ENSGALT00000094750|m.6004:231-303
ENSGALG00000045878	0.052944482	0.37315226	-2.605766007	1.87E-06	5.80E-06	down	yes	0.108390001	0.029801866	0.020641578	0.356743646	0.364376718	0.398336417	12	3320193	3327844	-	ENSGALG00000045878	protein_coding	--	--	--	--	--	3889	XP_015148351.1	XP_015148351.1 maestro heat-like repeat-containing protein family member 7 isoform X1 [Gallus gallus]	_	_	9031.ENSGALP00000033798	annotation not avaliable	_	KOG2032	_	_
ENSGALG00000045898	1.605893941	0.304880079	2.35945812	2.84E-17	2.23E-16	up	yes	1.786679376	1.426958698	1.604043749	0.378031618	0.340694275	0.195914342	7	11182555	11193986	+	ENSGALG00000045898	protein_coding	--	--	--	ko:K11581|SGOL2	--	3303	XP_004942657.1	XP_004942657.1 shugoshin 2 isoform X1 [Gallus gallus]	_	_	9031.ENSGALP00000013243	shugoshin-like 2 (S. pombe)	_	_	NOG289750	PF07557.8|Shugoshin_C|Shugoshin C terminus|ENSGALT00000098605|m.5860:909-929
ENSGALG00000046032	0.176655349	2.986148297	-4.004660278	2.01E-25	2.57E-24	down	yes	0.094091231	0.310444974	0.125429841	2.468609151	4.056188418	2.433647323	2	60692920	60705622	+	CD83	protein_coding	--	--	--	ko:K06510|CD83	--	2240	XP_418929.1	XP_418929.1 CD83 antigen [Gallus gallus]	_	_	_	_	_	_	_	PF07686.14|V-set|Immunoglobulin V-set domain|ENSGALT00000090207|m.885:36-129
ENSGALG00000046098	2.10962527	1.024893472	1.034326962	0.027801727	0.04474271	up	yes	2.513373927	2.106066224	1.709435659	1.48563022	0.887526966	0.701523232	5	17257123	17258502	+	ENSGALG00000046098	protein_coding	"GO:0000209|protein polyubiquitination; GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated; GO:0008283|cell population proliferation; GO:0016567|protein ubiquitination; GO:0044770|cell cycle phase transition; GO:0070979|protein K11-linked ubiquitination; GO:0071383|cellular response to steroid hormone stimulus; GO:0071385|cellular response to glucocorticoid stimulus"	GO:0005634|nucleus; GO:0005737|cytoplasm	GO:0003713|transcription coactivator activity; GO:0004842|ubiquitin-protein transferase activity; GO:0005524|ATP binding	--	--	587	XP_003641380.1	XP_003641380.1 ubiquitin-conjugating enzyme E2 L3 isoform X1 [Gallus gallus]	sp|Q3MHP1|UB2L3_BOVIN	sp|Q3MHP1|UB2L3_BOVIN Ubiquitin-conjugating enzyme E2 L3 OS=Bos taurus GN=UBE2L3 PE=2 SV=1	_	_	_	_	_	PF00179.23|UQ_con|Ubiquitin-conjugating enzyme|ENSGALT00000086955|m.2776:43-162;PF14461.3|Prok-E2_B|Prokaryotic E2 family B|ENSGALT00000086955|m.2776:67-149
ENSGALG00000046159	10.20763036	23.63426709	-1.210429773	4.88E-27	6.77E-26	down	yes	8.375179369	10.91140764	11.33630407	22.68056783	26.28147665	21.94075681	9	16326596	16343758	+	KNG1	protein_coding	GO:0006954|inflammatory response; GO:0007204|positive regulation of cytosolic calcium ion concentration; GO:0007596|blood coagulation; GO:0030195|negative regulation of blood coagulation; GO:0042311|vasodilation	GO:0005623|cell; GO:0072562|blood microparticle	GO:0004869|cysteine-type endopeptidase inhibitor activity	ko:K03898|KNG	ko04610|Complement and coagulation cascades	2397	XP_422766.2	XP_422766.2 kininogen-1 [Gallus gallus]	sp|P01044|KNG1_BOVIN	sp|P01044|KNG1_BOVIN Kininogen-1 OS=Bos taurus GN=KNG1 PE=1 SV=1	9031.ENSGALP00000014109	"Kinogen, HMW Fragments "	_	_	NOG72605	PF00031.18|Cystatin|Cystatin domain|ENSGALT00000088328|m.9156:2-75;PF00031.18|Cystatin|Cystatin domain|ENSGALT00000088328|m.9156:106-198;PF00031.18|Cystatin|Cystatin domain|ENSGALT00000088328|m.9156:227-321;PF00666.14|Cathelicidins|Cathelicidin|ENSGALT00000088328|m.9156:2-82;PF00666.14|Cathelicidins|Cathelicidin|ENSGALT00000088328|m.9156:120-201
ENSGALG00000046160	0	1.282551742	-7.014078224	2.58E-09	1.08E-08	down	yes	0	0	0	1.325843311	1.125956594	1.39585532	4	50962446	50963855	+	ENSGALG00000046160	protein_coding	GO:0006954|inflammatory response; GO:0006955|immune response; GO:0007186|G protein-coupled receptor signaling pathway; GO:0016525|negative regulation of angiogenesis; GO:0019221|cytokine-mediated signaling pathway; GO:0030168|platelet activation; GO:0030595|leukocyte chemotaxis; GO:0032496|response to lipopolysaccharide; GO:0042127|regulation of cell population proliferation; GO:0043950|positive regulation of cAMP-mediated signaling; GO:0045653|negative regulation of megakaryocyte differentiation; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0070098|chemokine-mediated signaling pathway; GO:0090023|positive regulation of neutrophil chemotaxis	GO:0005615|extracellular space	GO:0008009|chemokine activity; GO:0008201|heparin binding; GO:0045236|CXCR chemokine receptor binding; GO:0048248|CXCR3 chemokine receptor binding	--	--	1166	XP_420608.1	XP_420608.1 growth-regulated alpha protein [Gallus gallus]	sp|P30034|PLF4_PIG	sp|P30034|PLF4_PIG Platelet factor 4 OS=Sus scrofa GN=PF4 PE=1 SV=2	9031.ENSGALP00000040602	similar to K60 protein	_	_	NOG44673	_
ENSGALG00000046180	0.411100929	0.956735813	-1.19895563	6.91E-05	0.000173349	down	yes	0.530298912	0.388815623	0.314188253	0.786802179	1.118566834	0.964838427	6	28664613	28683067	+	TDRD1	protein_coding	GO:0007275|multicellular organism development; GO:0007281|germ cell development; GO:0007283|spermatogenesis; GO:0031047|gene silencing by RNA; GO:0034587|piRNA metabolic process; GO:0043046|DNA methylation involved in gamete generation; GO:0051321|meiotic cell cycle	GO:0005737|cytoplasm; GO:0033391|chromatoid body; GO:0043186|P granule; GO:0071546|pi-body	GO:0046872|metal ion binding	ko:K18405|TDRD1_4_6_7	--	3539	XP_421768.6	XP_421768.6 tudor domain-containing protein 1 [Gallus gallus]	sp|Q9BXT4|TDRD1_HUMAN	sp|Q9BXT4|TDRD1_HUMAN Tudor domain-containing protein 1 OS=Homo sapiens GN=TDRD1 PE=1 SV=2	9031.ENSGALP00000014576	annotation not avaliable	_	KOG2039	_	PF00567.21|TUDOR|Tudor domain|ENSGALT00000092521|m.5317:167-290;PF00567.21|TUDOR|Tudor domain|ENSGALT00000092521|m.5317:373-491;PF00567.21|TUDOR|Tudor domain|ENSGALT00000092521|m.5317:593-709;PF00567.21|TUDOR|Tudor domain|ENSGALT00000092521|m.5317:797-915;PF01753.15|zf-MYND|MYND finger|ENSGALT00000092521|m.5317:76-112
ENSGALG00000046217	13.30900487	1.705863832	2.956479323	7.00E-110	1.11E-107	up	yes	13.38430585	14.69187762	11.85083115	1.830063284	1.863353147	1.424175065	31	4922652	4930376	-	PIT54	protein_coding	GO:0007275|multicellular organism development; GO:0042494|detection of bacterial lipoprotein; GO:0045087|innate immune response; GO:0050829|defense response to Gram-negative bacterium; GO:0050830|defense response to Gram-positive bacterium; GO:2000483|negative regulation of interleukin-8 secretion	GO:0005615|extracellular space; GO:0005622|intracellular; GO:0005737|cytoplasm; GO:0016020|membrane; GO:0031012|extracellular matrix	GO:0001968|fibronectin binding; GO:0005044|scavenger receptor activity; GO:0043236|laminin binding; GO:0050840|extracellular matrix binding	--	--	2740	XP_021237384.1	XP_021237384.1 soluble scavenger receptor cysteine-rich domain-containing protein SSC5D-like [Numida meleagris]	sp|A1L4H1|SRCRL_HUMAN	sp|A1L4H1|SRCRL_HUMAN Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D OS=Homo sapiens GN=SSC5D PE=1 SV=3	_	_	_	_	_	PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000086453|m.14221:71-167;PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000086453|m.14221:180-277;PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000086453|m.14221:290-387;PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000086453|m.14221:401-496
ENSGALG00000046223	1.194157681	0.346425153	1.756353265	1.13E-05	3.16E-05	up	yes	1.508908623	1.062079788	1.011484632	0.431355666	0.214836424	0.393083369	17	9147825	9149878	+	GPR21	protein_coding	GO:0040018|positive regulation of multicellular organism growth; GO:0042593|glucose homeostasis; GO:0046627|negative regulation of insulin receptor signaling pathway	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	"GO:0001588|dopamine neurotransmitter receptor activity, coupled via Gs"	ko:K04318|GPR21	--	1746	XP_015135071.1	XP_015135071.1 probable G-protein coupled receptor 21 [Gallus gallus]	sp|Q99679|GPR21_HUMAN	sp|Q99679|GPR21_HUMAN Probable G-protein coupled receptor 21 OS=Homo sapiens GN=GPR21 PE=2 SV=1	59729.ENSTGUP00000018277	G protein-coupled receptor 21	_	KOG3656	_	PF00001.18|7tm_1|7 transmembrane receptor (rhodopsin family)|ENSGALT00000085108|m.12371:45-303;PF13853.3|7tm_4|Olfactory receptor|ENSGALT00000085108|m.12371:37-163
ENSGALG00000046262	0.336115009	0.88907463	-1.377189371	0.006154442	0.011322186	down	yes	0.226506563	0.415187021	0.366651444	0.596400232	1.522902799	0.54792086	15	9958937	9971701	-	ENSGALG00000046262	protein_coding	--	--	--	--	--	1861	XP_415279.4	XP_415279.4 coiled-coil domain-containing protein 60 [Gallus gallus]	sp|Q8IWA6|CCD60_HUMAN	sp|Q8IWA6|CCD60_HUMAN Coiled-coil domain-containing protein 60 OS=Homo sapiens GN=CCDC60 PE=1 SV=2	9031.ENSGALP00000011914	annotation not avaliable	_	_	NOG46618	PF15769.2|DUF4698|Domain of unknown function (DUF4698)|ENSGALT00000085721|m.10963:4-214;PF15769.2|DUF4698|Domain of unknown function (DUF4698)|ENSGALT00000085721|m.10963:218-389
ENSGALG00000046326	1.40042546	0.31327253	2.125307599	2.98E-12	1.60E-11	up	yes	1.463641364	1.276170196	1.46146482	0.245513778	0.414592364	0.279711447	1	135054624	135066732	+	IL1R2	protein_coding	--	GO:0005576|extracellular region; GO:0005886|plasma membrane; GO:0016021|integral component of membrane	"GO:0004910|interleukin-1, type II, blocking receptor activity"	"ko:K04387|IL1R2,CD121b"	ko04010|MAPK signaling pathway; ko04060|Cytokine-cytokine receptor interaction; ko04640|Hematopoietic cell lineage; ko05146|Amoebiasis; ko05166|HTLV-I infection; ko05202|Transcriptional misregulation in cancer; ko05418|Fluid shear stress and atherosclerosis	2664	XP_416914.3	XP_416914.3 interleukin-1 receptor type 2 isoform X1 [Gallus gallus]	sp|Q29612|IL1R2_CHLAE	sp|Q29612|IL1R2_CHLAE Interleukin-1 receptor type 2 OS=Chlorocebus aethiops GN=IL1R2 PE=1 SV=1	9031.ENSGALP00000029598	"interleukin 1 receptor, type II"	_	_	NOG44340	PF00047.22|ig|Immunoglobulin domain|ENSGALT00000088120|m.3712:275-370
ENSGALG00000046331	0.557613761	0.188052254	1.519028448	0.000907206	0.001923117	up	yes	0.462670826	0.600177307	0.60999315	0.073629259	0.232249711	0.258277791	31	4945555	4960499	-	ENSGALG00000046331	protein_coding	GO:0006898|receptor-mediated endocytosis; GO:0007275|multicellular organism development; GO:0015031|protein transport; GO:0016032|viral process; GO:0030855|epithelial cell differentiation; GO:0043152|induction of bacterial agglutination; GO:0044267|cellular protein metabolic process; GO:0045087|innate immune response; GO:0050829|defense response to Gram-negative bacterium; GO:0050830|defense response to Gram-positive bacterium; GO:0051607|defense response to virus; GO:0061844|antimicrobial humoral immune response mediated by antimicrobial peptide	GO:0005576|extracellular region; GO:0005615|extracellular space; GO:0005737|cytoplasm; GO:0019898|extrinsic component of membrane; GO:0030670|phagocytic vesicle membrane; GO:0042589|zymogen granule membrane; GO:0070062|extracellular exosome	GO:0001530|lipopolysaccharide binding; GO:0003677|DNA binding; GO:0005044|scavenger receptor activity; GO:0008329|signaling pattern recognition receptor activity; GO:0035375|zymogen binding; GO:0038187|pattern recognition receptor activity; GO:0048306|calcium-dependent protein binding; GO:0070891|lipoteichoic acid binding; GO:1904399|heparan sulfate binding	--	--	2961	NP_001305912.1	NP_001305912.1 deleted in malignant brain tumors 1 protein-like precursor [Gallus gallus]	sp|Q9UGM3|DMBT1_HUMAN	sp|Q9UGM3|DMBT1_HUMAN Deleted in malignant brain tumors 1 protein OS=Homo sapiens GN=DMBT1 PE=1 SV=2	9031.ENSGALP00000014870	PIT 54 protein 	_	_	NOG83796	PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000084648|m.14224:24-120;PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000084648|m.14224:131-228;PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000084648|m.14224:239-335;PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000084648|m.14224:347-444;PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000084648|m.14224:455-552;PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000084648|m.14224:564-659;PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000084648|m.14224:671-768;PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000084648|m.14224:779-876;PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000084648|m.14224:887-984
ENSGALG00000046448	1.527970648	0.66605385	1.185817897	0.010335763	0.018242335	up	yes	1.85455179	1.399751895	1.329608257	0.943793224	0.323589024	0.730779302	33	7742132	7746429	-	ZNF385A	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated; GO:0006915|apoptotic process; GO:0006974|cellular response to DNA damage stimulus; GO:0007049|cell cycle; GO:0007599|hemostasis; GO:0007611|learning or memory; GO:0007626|locomotory behavior; GO:0008298|intracellular mRNA localization; GO:0010609|mRNA localization resulting in posttranscriptional regulation of gene expression; GO:0030220|platelet formation; GO:0035855|megakaryocyte development; GO:0045600|positive regulation of fat cell differentiation; GO:0070889|platelet alpha granule organization; GO:0072332|intrinsic apoptotic signaling pathway by p53 class mediator; GO:1902164|positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; GO:1902166|negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; GO:2000765|regulation of cytoplasmic translation"	GO:0000790|nuclear chromatin; GO:0005730|nucleolus; GO:0005737|cytoplasm; GO:0030425|dendrite; GO:0043025|neuronal cell body	GO:0002039|p53 binding; GO:0003723|RNA binding; GO:0003730|mRNA 3'-UTR binding; GO:0008270|zinc ion binding	--	--	966	XP_025001297.1	XP_025001297.1 zinc finger protein 385A isoform X1 [Gallus gallus]	sp|Q8VD12|Z385A_MOUSE	sp|Q8VD12|Z385A_MOUSE Zinc finger protein 385A OS=Mus musculus GN=Znf385a PE=1 SV=2	_	_	_	_	_	PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000090197|m.15847:59-81;PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000090197|m.15847:175-199;PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000090197|m.15847:234-258;PF12171.5|zf-C2H2_jaz|Zinc-finger double-stranded RNA-binding|ENSGALT00000090197|m.15847:234-259
ENSGALG00000046517	0.594983395	0.2038685	1.500171539	0.001104133	0.002308973	up	yes	0.686600993	0.389741763	0.708607427	0.149959579	0.280307802	0.181338118	2	133816999	133819377	+	ENSGALG00000046517	protein_coding	--	--	--	--	--	2379	XP_012997796.1	XP_012997796.1 LOW QUALITY PROTEIN: uncharacterized protein LOC101788591 [Cavia porcellus]	_	_	_	_	_	_	_	PF00078.24|RVT_1|Reverse transcriptase (RNA-dependent DNA polymerase)|ENSGALT00000088981|m.2425:193-356;PF00075.21|RNase_H|RNase H|ENSGALT00000088981|m.2425:606-737;PF00077.17|RVP|Retroviral aspartyl protease|ENSGALT00000088981|m.2425:18-111
ENSGALG00000046593	1.34895474	6.595100134	-2.281083025	1.08E-06	3.44E-06	down	yes	0.823298267	0.965828807	2.257737146	8.175608803	5.665639326	5.944052275	5	9241993	9243150	-	ENSGALG00000046593	protein_coding	--	GO:0005576|extracellular region	GO:0005179|hormone activity	ko:K12333|ADM	--	320	XP_015719488.1	XP_015719488.1 PREDICTED: ADM [Coturnix japonica]	sp|O77559|ADML_CANLF	sp|O77559|ADML_CANLF ADM OS=Canis lupus familiaris GN=ADM PE=2 SV=2	9031.ENSGALP00000009074	adrenomedullin	_	_	NOG46109	PF00214.16|Calc_CGRP_IAPP|Calcitonin / CGRP / IAPP family|ENSGALT00000088854|m.2452:33-82
ENSGALG00000046721	1.790176534	0.844936807	1.0742487	0.000639721	0.001390992	up	yes	2.214776961	1.076290167	2.079462474	0.639343797	0.937048021	0.958418603	2	144074164	144076209	+	ENSGALG00000046721	protein_coding	--	--	--	--	--	2046	XP_014793918.1	XP_014793918.1 PREDICTED: uncharacterized protein LOC106885910 [Calidris pugnax]	_	_	_	_	_	_	_	PF00665.23|rve|Integrase core domain|ENSGALT00000090532|m.2586:460-571;PF00075.21|RNase_H|RNase H|ENSGALT00000090532|m.2586:234-377
ENSGALG00000046724	1.55638047	0.516877089	1.57189633	5.24E-08	1.93E-07	up	yes	1.509003336	1.742962932	1.417175141	0.629812583	0.35154285	0.569275834	4	10925877	10932243	-	PRRG3	protein_coding	--	GO:0005576|extracellular region; GO:0016021|integral component of membrane	GO:0005509|calcium ion binding	--	--	2549	XP_010713586.1	XP_010713586.1 PREDICTED: transmembrane gamma-carboxyglutamic acid protein 3 [Meleagris gallopavo]	sp|Q6PAQ9|TMG3_MOUSE	sp|Q6PAQ9|TMG3_MOUSE Transmembrane gamma-carboxyglutamic acid protein 3 OS=Mus musculus GN=Prrg3 PE=2 SV=2	_	_	_	_	_	PF00594.17|Gla|Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain|ENSGALT00000099755|m.16405:62-102
ENSGALG00000046739	1.038946175	0.301673915	1.750831329	6.46E-05	0.000162953	up	yes	1.137002491	1.25047682	0.729359214	0.416426652	0.1656717	0.322923392	16	628316	630076	+	ENSGALG00000046739	protein_coding	--	--	--	--	--	1761	XP_025011592.1	XP_025011592.1 zinc finger protein 316-like [Gallus gallus]	_	_	_	_	_	_	_	"PF00096.23|zf-C2H2|Zinc finger, C2H2 type|ENSGALT00000106725|m.11207:512-534"
ENSGALG00000046817	0.364458744	0.996534421	-1.426517827	0.002848145	0.005559633	down	yes	0.449303861	0.239585441	0.404486931	1.121577529	1.001570741	0.866454995	8	11602708	11637021	+	ENSGALG00000046817	protein_coding	GO:0001502|cartilage condensation; GO:0001503|ossification; GO:0002063|chondrocyte development; GO:0006029|proteoglycan metabolic process; GO:0007601|visual perception; GO:0007605|sensory perception of sound; GO:0030198|extracellular matrix organization; GO:0030199|collagen fibril organization; GO:0030574|collagen catabolic process; GO:0035987|endodermal cell differentiation; GO:0035989|tendon development; GO:0042472|inner ear morphogenesis; GO:0048704|embryonic skeletal system morphogenesis; GO:0050910|detection of mechanical stimulus involved in sensory perception of sound; GO:0055010|ventricular cardiac muscle tissue morphogenesis	GO:0005576|extracellular region; GO:0005592|collagen type XI trimer; GO:0005615|extracellular space; GO:0005788|endoplasmic reticulum lumen	"GO:0005201|extracellular matrix structural constituent; GO:0030674|protein binding, bridging; GO:0046872|metal ion binding; GO:0050840|extracellular matrix binding"	ko:K19721|COL5AS	ko04974|Protein digestion and absorption	1290	XP_021260222.1	XP_021260222.1 collagen alpha-1(XI) chain isoform X1 [Numida meleagris]	sp|P12107|COBA1_HUMAN	sp|P12107|COBA1_HUMAN Collagen alpha-1(XI) chain OS=Homo sapiens GN=COL11A1 PE=1 SV=4	9031.ENSGALP00000008307	Alpha-1 type XI collagen Fragment 	_	KOG3544	_	PF00054.20|Laminin_G_1|Laminin G domain|ENSGALT00000063775|m.7374:205-250
ENSGALG00000046904	128.6518047	42.53053721	1.596673674	3.49E-42	9.69E-41	up	yes	120.9943528	129.8177979	135.1432635	49.38231212	36.41585895	41.79344055	1	48172580	48173552	-	ENSGALG00000046904	protein_coding	GO:0006334|nucleosome assembly; GO:0006335|DNA replication-dependent nucleosome assembly; GO:0051290|protein heterotetramerization; GO:0060968|regulation of gene silencing	"GO:0000784|nuclear chromosome, telomeric region; GO:0000786|nucleosome; GO:0000788|nuclear nucleosome; GO:0005634|nucleus; GO:0016020|membrane; GO:0032991|protein-containing complex; GO:0070062|extracellular exosome"	GO:0031492|nucleosomal DNA binding; GO:0042393|histone binding; GO:0045296|cadherin binding; GO:0046982|protein heterodimerization activity	ko:K11253|H3	ko05034|Alcoholism; ko05202|Transcriptional misregulation in cancer; ko05322|Systemic lupus erythematosus	297	NP_001091119.1	"NP_001091119.1 histone cluster 1, H3g protein L homeolog [Xenopus laevis]"	sp|P68432|H31_BOVIN	sp|P68432|H31_BOVIN Histone H3.1 OS=Bos taurus PE=1 SV=2	_	_	_	_	_	_
ENSGALG00000046914	0.537901148	1.13792503	-1.067040893	0.029363058	0.047061126	down	yes	0.141547587	0.959991024	0.512164833	1.024925214	1.203603392	1.185246485	4	68455867	68468029	-	ENSGALG00000046914	protein_coding	GO:0031032|actomyosin structure organization	--	GO:0003779|actin binding; GO:0046872|metal ion binding	--	--	1342	XP_015140950.1	XP_015140950.1 LIM and calponin homology domains-containing protein 1 isoform X3 [Gallus gallus]	sp|Q9UPQ0|LIMC1_HUMAN	sp|Q9UPQ0|LIMC1_HUMAN LIM and calponin homology domains-containing protein 1 OS=Homo sapiens GN=LIMCH1 PE=1 SV=4	9031.ENSGALP00000023016	LIM and calponin homology domains 1	_	KOG1704	_	PF00412.19|LIM|LIM domain|ENSGALT00000098741|m.1187:145-206
ENSGALG00000047024	0.838586854	2.227415747	-1.398699123	5.42E-32	9.57E-31	down	yes	0.863580154	0.881482707	0.7706977	2.060467347	2.34057268	2.281207215	11	18321016	18333462	+	ZNF469	protein_coding	--	--	--	--	--	12447	XP_004944342.1	XP_004944342.1 zinc finger protein 469 [Gallus gallus]	_	_	_	_	_	_	_	_
ENSGALG00000047103	20.31579713	8.930748732	1.184844374	1.92E-25	2.47E-24	up	yes	22.38380853	17.81578953	20.74779333	9.077800615	9.322770095	8.391675485	4	50022591	50024186	+	UTP3	protein_coding	"GO:0000462|maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); GO:0007420|brain development; GO:0016569|covalent chromatin modification"	GO:0005634|nucleus; GO:0005730|nucleolus; GO:0032040|small-subunit processome	GO:0003723|RNA binding	"ko:K14767|UTP3,SAS10"	--	1596	XP_015131905.1	XP_015131905.1 something about silencing protein 10 [Gallus gallus]	sp|Q9JI13|SAS10_MOUSE	sp|Q9JI13|SAS10_MOUSE Something about silencing protein 10 OS=Mus musculus GN=Utp3 PE=1 SV=1	9031.ENSGALP00000018819	"UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)"	_	KOG3118	_	PF09368.7|Sas10|Sas10 C-terminal domain|ENSGALT00000095645|m.670:458-530;PF04000.12|Sas10_Utp3|Sas10/Utp3/C1D family|ENSGALT00000095645|m.670:272-349
ENSGALG00000047126	151.7888568	62.76673322	1.273859064	3.66E-40	9.26E-39	up	yes	150.0989454	157.7890435	147.4785814	69.97630105	53.33540593	64.9884927	1	48116062	48116583	+	ENSGALG00000047126	protein_coding	"GO:0006334|nucleosome assembly; GO:0006335|DNA replication-dependent nucleosome assembly; GO:0006336|DNA replication-independent nucleosome assembly; GO:0006352|DNA-templated transcription, initiation; GO:0045653|negative regulation of megakaryocyte differentiation; GO:0051290|protein heterotetramerization"	"GO:0000784|nuclear chromosome, telomeric region; GO:0000788|nuclear nucleosome; GO:0005654|nucleoplasm; GO:0016020|membrane; GO:0031012|extracellular matrix; GO:0032991|protein-containing complex; GO:0070062|extracellular exosome"	GO:0003677|DNA binding; GO:0003723|RNA binding; GO:0019904|protein domain specific binding; GO:0042393|histone binding; GO:0046982|protein heterodimerization activity	--	--	522	XP_006872880.1	XP_006872880.1 PREDICTED: histone H3.1-like [Chrysochloris asiatica]	sp|P62803|H4_BOVIN	sp|P62803|H4_BOVIN Histone H4 OS=Bos taurus PE=1 SV=2	9031.ENSGALP00000037292	"Histone H4 ; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin,  [...] "	COG2036	KOG3467	_	PF15511.3|CENP-T_C|Centromere kinetochore component CENP-T histone fold|ENSGALT00000046737|m.1187:45-106;PF02969.14|TAF|TATA box binding protein associated factor (TAF)|ENSGALT00000046737|m.1187:69-102
ENSGALG00000047182	1.152748864	0.101673254	3.380183932	1.02E-16	7.69E-16	up	yes	0.960514645	1.173750287	1.32398166	0.068818256	0.108537152	0.127664353	31	2208184	2214141	+	ACHE	protein_coding	GO:0010842|retina layer formation; GO:0042135|neurotransmitter catabolic process	GO:0005576|extracellular region; GO:0005886|plasma membrane; GO:0030054|cell junction; GO:0045202|synapse	GO:0003990|acetylcholinesterase activity; GO:0052689|carboxylic ester hydrolase activity	ko:K01049|ACHE	ko00564|Glycerophospholipid metabolism; ko04725|Cholinergic synapse	2304	XP_025001874.1	XP_025001874.1 LOW QUALITY PROTEIN: acetylcholinesterase [Gallus gallus]	sp|P36196|ACES_CHICK	sp|P36196|ACES_CHICK Acetylcholinesterase OS=Gallus gallus GN=ACHE PE=2 SV=1	13616.ENSMODP00000006010	acetylcholinesterase (Yt blood group)	COG2272	KOG4389	_	PF00135.25|COesterase|Carboxylesterase family|ENSGALT00000100625|m.13979:30-336;PF00135.25|COesterase|Carboxylesterase family|ENSGALT00000100625|m.13979:506-716;PF08674.7|AChE_tetra|Acetylcholinesterase tetramerisation domain|ENSGALT00000100625|m.13979:731-766;PF07859.10|Abhydrolase_3|alpha/beta hydrolase fold|ENSGALT00000100625|m.13979:140-231
ENSGALG00000047196	4.109434634	1.422518295	1.523892786	4.01E-15	2.71E-14	up	yes	4.364312431	4.234037398	3.729954074	1.281270801	1.599771838	1.386512246	4	77015911	77017890	-	ENSGALG00000047196	protein_coding	GO:0006310|DNA recombination; GO:0015074|DNA integration; GO:0044826|viral genome integration into host DNA; GO:0046718|viral entry into host cell; GO:0075713|establishment of integrated proviral latency	GO:0019013|viral nucleocapsid	GO:0000166|nucleotide binding; GO:0003677|DNA binding; GO:0003887|DNA-directed DNA polymerase activity; GO:0003964|RNA-directed DNA polymerase activity; GO:0004190|aspartic-type endopeptidase activity; GO:0004523|RNA-DNA hybrid ribonuclease activity; GO:0008270|zinc ion binding; GO:0039660|structural constituent of virion	--	--	1980	XP_010161201.1	"XP_010161201.1 PREDICTED: endogenous retrovirus group K member 18 Pol protein-like, partial [Antrostomus carolinensis]"	sp|P11283|POL_MMTVC	sp|P11283|POL_MMTVC Gag-Pro-Pol polyprotein OS=Mouse mammary tumor virus (strain C3H) GN=gag-pro-pol PE=1 SV=2	9031.ENSGALP00000002672	annotation not avaliable	_	_	NOG45983	PF00078.24|RVT_1|Reverse transcriptase (RNA-dependent DNA polymerase)|ENSGALT00000096012|m.1349:357-525;PF00692.16|dUTPase|dUTPase|ENSGALT00000096012|m.1349:53-176;PF00077.17|RVP|Retroviral aspartyl protease|ENSGALT00000096012|m.1349:203-288;PF06817.11|RVT_thumb|Reverse transcriptase thumb domain|ENSGALT00000096012|m.1349:532-595
ENSGALG00000047199	7.349776013	17.64659497	-1.262473385	2.28E-21	2.33E-20	down	yes	7.374559297	6.592962515	8.081806227	15.94234693	21.14272094	15.85471703	6	17399196	17404437	+	ENSGALG00000047199	protein_coding	GO:0006805|xenobiotic metabolic process; GO:0008202|steroid metabolic process; GO:0016098|monoterpenoid metabolic process; GO:0017144|drug metabolic process; GO:0019373|epoxygenase P450 pathway; GO:0019627|urea metabolic process; GO:0032787|monocarboxylic acid metabolic process; GO:0042737|drug catabolic process; GO:0042738|exogenous drug catabolic process; GO:0043603|cellular amide metabolic process; GO:0055114|oxidation-reduction process; GO:0070989|oxidative demethylation; GO:0097267|omega-hydroxylase P450 pathway	GO:0005789|endoplasmic reticulum membrane; GO:0031090|organelle membrane; GO:0043231|intracellular membrane-bounded organelle	GO:0001567|cholesterol 25-hydroxylase activity; GO:0004497|monooxygenase activity; GO:0005506|iron ion binding; GO:0008144|drug binding; GO:0008392|arachidonic acid epoxygenase activity; GO:0008395|steroid hydroxylase activity; GO:0016491|oxidoreductase activity; GO:0018675|(S)-limonene 6-monooxygenase activity; GO:0018676|(S)-limonene 7-monooxygenase activity; GO:0019825|oxygen binding; GO:0020037|heme binding; GO:0034875|caffeine oxidase activity; GO:0052741|(R)-limonene 6-monooxygenase activity	ko:K07413|CYP2C	ko00140|Steroid hormone biosynthesis; ko00590|Arachidonic acid metabolism; ko00591|Linoleic acid metabolism; ko00830|Retinol metabolism; ko01100|Metabolic pathways; ko04726|Serotonergic synapse; ko04750|Inflammatory mediator regulation of TRP channels; ko05204|Chemical carcinogenesis	1922	XP_015144012.1	XP_015144012.1 cytochrome P450 2C9-like [Gallus gallus]	sp|P11712|CP2C9_HUMAN	sp|P11712|CP2C9_HUMAN Cytochrome P450 2C9 OS=Homo sapiens GN=CYP2C9 PE=1 SV=3	59729.ENSTGUP00000007475	Cytochrome P450 2C8 (EC 1.14.14.1)(CYPIIC8)(P450 form 1)(P450 MP-12/MP-20)(P450 IIC2)(S-meph [...] 	COG2124	KOG0156	_	PF00067.19|p450|Cytochrome P450|ENSGALT00000063525|m.4757:43-499
ENSGALG00000047242	0.795085467	0.329945575	1.243838154	0.000135108	0.0003252	up	yes	0.818080914	0.905847044	0.661328442	0.282599682	0.402784259	0.304452784	30	1143449	1161104	-	MAST1	protein_coding	GO:0006468|protein phosphorylation; GO:0007010|cytoskeleton organization; GO:0018105|peptidyl-serine phosphorylation; GO:0035556|intracellular signal transduction	GO:0005622|intracellular; GO:0005737|cytoplasm; GO:0005856|cytoskeleton; GO:0005886|plasma membrane	GO:0000287|magnesium ion binding; GO:0004674|protein serine/threonine kinase activity; GO:0005524|ATP binding	--	--	2238	XP_025001506.1	XP_025001506.1 LOW QUALITY PROTEIN: microtubule-associated serine/threonine-protein kinase 1-like [Gallus gallus]	sp|Q9Y2H9|MAST1_HUMAN	sp|Q9Y2H9|MAST1_HUMAN Microtubule-associated serine/threonine-protein kinase 1 OS=Homo sapiens GN=MAST1 PE=1 SV=2	_	_	_	_	_	PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000090740|m.13763:144-417;PF08926.8|DUF1908|Domain of unknown function (DUF1908)|ENSGALT00000090740|m.13763:23-54;PF08926.8|DUF1908|Domain of unknown function (DUF1908)|ENSGALT00000090740|m.13763:50-121;PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000090740|m.13763:146-398
ENSGALG00000047265	1.86236351	3.926172817	-1.071933009	0.030824015	0.049148399	down	yes	2.187038578	0.768081507	2.631970444	3.857470875	3.605235453	4.315812122	28	2872042	2891890	-	ENSGALG00000047265	protein_coding	--	--	--	--	--	2813	XP_004948894.1	XP_004948894.1 uncharacterized protein KIAA1958 [Gallus gallus]	_	_	_	_	_	_	_	PF12012.5|DUF3504|Domain of unknown function (DUF3504)|ENSGALT00000100895|m.10034:522-667
ENSGALG00000047291	1.01409995	0.295229386	1.746390759	2.86E-05	7.60E-05	up	yes	1.22599398	0.801193346	1.015112526	0.330828884	0.158111784	0.396747488	6	36284761	36286737	+	ENSGALG00000047291	protein_coding	--	--	--	--	--	1977	RMC14216.1	RMC14216.1 hypothetical protein DUI87_09307 [Hirundo rustica rustica]	_	_	_	_	_	_	_	PF00078.24|RVT_1|Reverse transcriptase (RNA-dependent DNA polymerase)|ENSGALT00000095022|m.5541:410-632;PF14529.3|Exo_endo_phos_2|Endonuclease-reverse transcriptase|ENSGALT00000095022|m.5541:24-98
ENSGALG00000047313	1.381835238	0.290320236	2.212414843	1.28E-11	6.53E-11	up	yes	1.038816653	1.12838707	1.97830199	0.267735427	0.273898793	0.329326489	5	182102	189519	-	ENSGALG00000047313	protein_coding	--	--	--	--	--	1778	XP_015128119.1	XP_015128119.1 glycine N-acyltransferase-like protein 3 isoform X1 [Gallus gallus]	_	_	_	_	_	_	_	"PF06021.8|Gly_acyl_tr_N|Aralkyl acyl-CoA:amino acid N-acyltransferase|ENSGALT00000108378|m.2014:268-350;PF08444.7|Gly_acyl_tr_C|Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region|ENSGALT00000108378|m.2014:353-430"
ENSGALG00000047317	5.724886107	0.887712878	2.675438839	1.41E-15	9.85E-15	up	yes	7.173503217	5.447462317	4.553692786	0.867310791	0.810598372	0.98522947	2	148911953	148916500	-	ENSGALG00000047317	protein_coding	--	GO:0005882|intermediate filament	GO:0005200|structural constituent of cytoskeleton	--	--	617	XP_015138673.1	XP_015138673.1 feather keratin 1-like isoform X1 [Gallus gallus]	sp|P02451|KRFT_LARNO	sp|P02451|KRFT_LARNO Feather keratin OS=Larus novaehollandiae PE=1 SV=1	9031.ENSGALP00000034768	annotation not avaliable	_	_	NOG231326	_
ENSGALG00000047359	21.31182555	9.009993608	1.241132649	9.17E-44	2.68E-42	up	yes	22.07705014	20.27731015	21.58111636	9.394547623	8.244570389	9.390862814	2	130663345	130679919	-	MAF1	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0016480|negative regulation of transcription by RNA polymerase III"	GO:0005622|intracellular; GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005730|nucleolus; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0030424|axon; GO:0030425|dendrite; GO:0043231|intracellular membrane-bounded organelle; GO:0048471|perinuclear region of cytoplasm; GO:0060077|inhibitory synapse	GO:0000994|RNA polymerase III core binding; GO:0001030|RNA polymerase III type 1 promoter DNA binding; GO:0001031|RNA polymerase III type 2 promoter DNA binding; GO:0001032|RNA polymerase III type 3 promoter DNA binding; GO:0050811|GABA receptor binding	--	--	1843	XP_025003875.1	XP_025003875.1 repressor of RNA polymerase III transcription MAF1 homolog [Gallus gallus]	sp|Q9H063|MAF1_HUMAN	sp|Q9H063|MAF1_HUMAN Repressor of RNA polymerase III transcription MAF1 homolog OS=Homo sapiens GN=MAF1 PE=1 SV=2	28377.ENSACAP00000007148	MAF1 homolog (S. cerevisiae)	COG5046	KOG3104	_	PF09174.7|Maf1|Maf1 regulator|ENSGALT00000108046|m.2302:63-229
ENSGALG00000047380	6.218300411	1.811476638	1.773730041	2.99E-22	3.20E-21	up	yes	4.932005504	8.498562969	5.22433276	1.73648435	1.714154981	1.983790584	16	2001694	2114403	+	ENSGALG00000047380	protein_coding	GO:0002474|antigen processing and presentation of peptide antigen via MHC class I	GO:0016021|integral component of membrane; GO:0042612|MHC class I protein complex	--	ko:K06751|MHC1	ko04144|Endocytosis; ko04145|Phagosome; ko04514|Cell adhesion molecules (CAMs); ko04612|Antigen processing and presentation; ko04940|Type I diabetes mellitus; ko05166|HTLV-I infection; ko05168|Herpes simplex infection; ko05169|Epstein-Barr virus infection; ko05203|Viral carcinogenesis; ko05320|Autoimmune thyroid disease; ko05330|Allograft rejection; ko05332|Graft-versus-host disease; ko05416|Viral myocarditis	2647	XP_025011645.1	"XP_025011645.1 class I histocompatibility antigen, F10 alpha chain-like isoform X2 [Gallus gallus]"	sp|P15979|HA1F_CHICK	"sp|P15979|HA1F_CHICK Class I histocompatibility antigen, F10 alpha chain OS=Gallus gallus PE=2 SV=1"	9031.ENSGALP00000021123	"PREDICTED: Gallus gallus similar to MHC Rfp-Y class I alpha chain (LOC417080), partial mRNA"	_	_	NOG42056	"PF00129.15|MHC_I|Class I Histocompatibility antigen, domains alpha 1 and 2|ENSGALT00000091250|m.11377:117-292;PF07654.12|C1-set|Immunoglobulin C1-set domain|ENSGALT00000091250|m.11377:310-378"
ENSGALG00000047393	8.437636192	3.215508466	1.389021101	6.70E-35	1.33E-33	up	yes	9.415916645	7.903292287	7.993699644	2.866019495	3.602754268	3.177751635	4	89737708	89761162	+	ENSGALG00000047393	protein_coding	GO:0035773|insulin secretion involved in cellular response to glucose stimulus; GO:0045055|regulated exocytosis; GO:0070164|negative regulation of adiponectin secretion; GO:0071468|cellular response to acidic pH; GO:2000008|regulation of protein localization to cell surface	GO:0000139|Golgi membrane; GO:0005741|mitochondrial outer membrane; GO:0005769|early endosome; GO:0005794|Golgi apparatus; GO:0005815|microtubule organizing center; GO:0030141|secretory granule; GO:0030658|transport vesicle membrane; GO:0031901|early endosome membrane; GO:0043231|intracellular membrane-bounded organelle; GO:0055037|recycling endosome; GO:0055038|recycling endosome membrane	GO:0017137|Rab GTPase binding; GO:0043015|gamma-tubulin binding	ko:K12484|RAB11FIP1_2_5	ko04144|Endocytosis	4986	XP_015141544.1	XP_015141544.1 rab11 family-interacting protein 5 isoform X3 [Gallus gallus]	sp|Q9BXF6|RFIP5_HUMAN	sp|Q9BXF6|RFIP5_HUMAN Rab11 family-interacting protein 5 OS=Homo sapiens GN=RAB11FIP5 PE=1 SV=1	_	_	_	_	_	PF00168.27|C2|C2 domain|ENSGALT00000104400|m.1709:295-406;PF09457.7|RBD-FIP|FIP domain|ENSGALT00000104400|m.1709:1607-1654
ENSGALG00000047483	16.89214737	2.072798625	3.020611284	2.30E-206	1.98E-203	up	yes	16.26607639	17.98494731	16.4254184	1.986864889	1.980318613	2.251212373	1	51440395	51445547	+	C1QTNF6	protein_coding	GO:0007204|positive regulation of cytosolic calcium ion concentration; GO:0010544|negative regulation of platelet activation; GO:0010628|positive regulation of gene expression; GO:0010906|regulation of glucose metabolic process; GO:0043410|positive regulation of MAPK cascade; GO:0051260|protein homooligomerization; GO:0051897|positive regulation of protein kinase B signaling; GO:0070208|protein heterotrimerization; GO:0090331|negative regulation of platelet aggregation; GO:2000860|positive regulation of aldosterone secretion	GO:0005581|collagen trimer; GO:0005615|extracellular space; GO:0005887|integral component of plasma membrane	GO:0005518|collagen binding	ko:K19470|C1QTNF6	--	3641	XP_425481.4	XP_425481.4 complement C1q tumor necrosis factor-related protein 6 [Gallus gallus]	sp|Q5XIG2|C1QT1_RAT	sp|Q5XIG2|C1QT1_RAT Complement C1q tumor necrosis factor-related protein 1 OS=Rattus norvegicus GN=C1qtnf1 PE=2 SV=1	9031.ENSGALP00000020335	C1q and tumor necrosis factor related protein 6	_	_	NOG44388	PF00386.18|C1q|C1q domain|ENSGALT00000107143|m.1458:126-254;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000107143|m.1458:77-118
ENSGALG00000047526	26.83884133	11.2676312	1.25139576	4.25E-17	3.29E-16	up	yes	34.6298376	22.69104885	23.19563754	11.94045478	10.88200249	10.98043632	5	123422	124480	-	ENSGALG00000047526	protein_coding	--	GO:0005887|integral component of plasma membrane	GO:0004930|G protein-coupled receptor activity	--	--	1059	XP_015128123.1	XP_015128123.1 probable G-protein coupled receptor 152 [Gallus gallus]	sp|Q96LA9|MRGX4_HUMAN	sp|Q96LA9|MRGX4_HUMAN Mas-related G-protein coupled receptor member X4 OS=Homo sapiens GN=MRGPRX4 PE=2 SV=2	_	_	_	_	_	PF00001.18|7tm_1|7 transmembrane receptor (rhodopsin family)|ENSGALT00000096586|m.1984:92-319;PF10328.6|7TM_GPCR_Srx|Serpentine type 7TM GPCR chemoreceptor Srx|ENSGALT00000096586|m.1984:84-262
ENSGALG00000047567	1.68123521	0.549068088	1.596981415	4.18E-06	1.23E-05	up	yes	1.565081855	1.836031	1.642592775	0.693360963	0.371390492	0.58245281	33	5508183	5509697	+	ENSGALG00000047567	protein_coding	--	--	--	--	--	1515	_	_	_	_	_	_	_	_	_	_
ENSGALG00000047617	37.87313876	18.49659834	1.033516127	3.67E-25	4.62E-24	up	yes	34.33525091	40.67596284	38.60820252	17.06093396	20.46642704	17.96243403	28	3504947	3508192	+	DDA1	protein_coding	GO:0032434|regulation of proteasomal ubiquitin-dependent protein catabolic process	GO:0080008|Cul4-RING E3 ubiquitin ligase complex	--	ko:K11792|DDA1	--	1286	XP_005278994.1	XP_005278994.1 DET1- and DDB1-associated protein 1 isoform X1 [Chrysemys picta bellii]	sp|Q5ZK14|DDA1_CHICK	sp|Q5ZK14|DDA1_CHICK DET1- and DDB1-associated protein 1 OS=Gallus gallus GN=DDA1 PE=3 SV=1	9031.ENSGALP00000001589	DET1- and DDB1-associated protein 1 ; May be involved in ubiquitination and subsequent prote [...] 	_	KOG4816	_	PF10172.6|DDA1|Det1 complexing ubiquitin ligase|ENSGALT00000105028|m.10245:67-129
ENSGALG00000047627	19.55735521	8.572032978	1.189057419	2.32E-15	1.59E-14	up	yes	21.14732051	20.87576167	16.64898344	7.732332826	10.69991366	7.283852447	16	2082890	2084768	-	ENSGALG00000047627	protein_coding	GO:0002474|antigen processing and presentation of peptide antigen via MHC class I	GO:0016021|integral component of membrane; GO:0042612|MHC class I protein complex	--	--	--	1338	XP_015157570.1	"XP_015157570.1 class I histocompatibility antigen, F10 alpha chain isoform X1 [Gallus gallus]"	sp|P15979|HA1F_CHICK	"sp|P15979|HA1F_CHICK Class I histocompatibility antigen, F10 alpha chain OS=Gallus gallus PE=2 SV=1"	9031.ENSGALP00000000235	similar to MHC Rfp-Y class I alpha chain	_	_	NOG42056	PF07654.12|C1-set|Immunoglobulin C1-set domain|ENSGALT00000054691|m.11401:7-73
ENSGALG00000047665	0.867012371	0.192108222	2.117469181	1.62E-05	4.45E-05	up	yes	0.887428869	0.840440506	0.873167738	0.166902381	0.175487437	0.233934848	16	626758	628182	+	ENSGALG00000047665	protein_coding	--	--	--	--	--	1425	_	_	_	_	_	_	_	_	_	"PF00096.23|zf-C2H2|Zinc finger, C2H2 type|ENSGALT00000107223|m.11206:376-398;PF13894.3|zf-C2H2_4|C2H2-type zinc finger|ENSGALT00000107223|m.11206:404-426;PF13912.3|zf-C2H2_6|C2H2-type zinc finger|ENSGALT00000107223|m.11206:320-342"
ENSGALG00000047713	1.553795883	0.252302982	2.575746098	3.66E-09	1.50E-08	up	yes	2.393517163	1.112278857	1.15559163	0.164846801	0.253322796	0.33873935	26	5549249	5553823	-	ENSGALG00000047713	protein_coding	GO:0009435|NAD biosynthetic process; GO:0034213|quinolinate catabolic process; GO:0046874|quinolinate metabolic process; GO:0051259|protein complex oligomerization	GO:0005737|cytoplasm; GO:0070062|extracellular exosome	GO:0004514|nicotinate-nucleotide diphosphorylase (carboxylating) activity; GO:0042803|protein homodimerization activity	"ko:K00767|nadC,QPRT"	ko00760|Nicotinate and nicotinamide metabolism; ko01100|Metabolic pathways	1563	XP_024999706.1	XP_024999706.1 nicotinate-nucleotide pyrophosphorylase [carboxylating] [Gallus gallus]	sp|Q5I0M2|NADC_RAT	sp|Q5I0M2|NADC_RAT Nicotinate-nucleotide pyrophosphorylase [carboxylating] OS=Rattus norvegicus GN=Qprt PE=2 SV=1	_	_	_	_	_	"PF01729.16|QRPTase_C|Quinolinate phosphoribosyl transferase, C-terminal domain|ENSGALT00000097821|m.8383:1-117"
ENSGALG00000047782	0.690188927	0.255978999	1.396431908	0.000105251	0.00025744	up	yes	0.806346661	0.515968645	0.748251475	0.187498153	0.220335854	0.36010299	32	585791	592586	-	ENSGALG00000047782	protein_coding	--	GO:0000159|protein phosphatase type 2A complex; GO:0005737|cytoplasm; GO:0016020|membrane; GO:0032991|protein-containing complex; GO:0043197|dendritic spine	GO:0005516|calmodulin binding; GO:0044877|protein-containing complex binding; GO:0051721|protein phosphatase 2A binding; GO:0070016|armadillo repeat domain binding	--	--	3594	XP_025000232.1	XP_025000232.1 LOW QUALITY PROTEIN: striatin-4 [Gallus gallus]	sp|P58404|STRN4_MOUSE	sp|P58404|STRN4_MOUSE Striatin-4 OS=Mus musculus GN=Strn4 PE=1 SV=2	_	_	_	_	_	"PF00400.29|WD40|WD domain, G-beta repeat|ENSGALT00000093409|m.14463:23-54;PF00400.29|WD40|WD domain, G-beta repeat|ENSGALT00000093409|m.14463:74-108"
ENSGALG00000047807	3.660302435	0.790969593	2.196079568	2.09E-24	2.53E-23	up	yes	3.591298938	3.428572266	3.961036101	0.773930546	0.554822501	1.04415573	31	4903146	4920106	+	DMBT1L	protein_coding	GO:0006898|receptor-mediated endocytosis; GO:0007275|multicellular organism development; GO:0015031|protein transport; GO:0016032|viral process; GO:0030855|epithelial cell differentiation; GO:0043152|induction of bacterial agglutination; GO:0044267|cellular protein metabolic process; GO:0045087|innate immune response; GO:0050829|defense response to Gram-negative bacterium; GO:0050830|defense response to Gram-positive bacterium; GO:0051607|defense response to virus; GO:0061844|antimicrobial humoral immune response mediated by antimicrobial peptide	GO:0005576|extracellular region; GO:0005615|extracellular space; GO:0005737|cytoplasm; GO:0019898|extrinsic component of membrane; GO:0030670|phagocytic vesicle membrane; GO:0042589|zymogen granule membrane; GO:0070062|extracellular exosome	GO:0001530|lipopolysaccharide binding; GO:0003677|DNA binding; GO:0005044|scavenger receptor activity; GO:0008329|signaling pattern recognition receptor activity; GO:0035375|zymogen binding; GO:0038187|pattern recognition receptor activity; GO:0048306|calcium-dependent protein binding; GO:0070891|lipoteichoic acid binding; GO:1904399|heparan sulfate binding	--	--	2786	NP_001305912.1	NP_001305912.1 deleted in malignant brain tumors 1 protein-like precursor [Gallus gallus]	sp|Q9UGM3|DMBT1_HUMAN	sp|Q9UGM3|DMBT1_HUMAN Deleted in malignant brain tumors 1 protein OS=Homo sapiens GN=DMBT1 PE=1 SV=2	9031.ENSGALP00000014870	PIT 54 protein 	_	_	NOG83796	PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000083389|m.14218:69-166;PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000083389|m.14218:177-273;PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000083389|m.14218:285-382;PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000083389|m.14218:393-490;PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000083389|m.14218:502-597;PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000083389|m.14218:609-706;PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000083389|m.14218:717-814;PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000083389|m.14218:825-922
ENSGALG00000047859	1.993050487	0.883165034	1.165200106	0.001096166	0.002293503	up	yes	2.099450586	1.539318993	2.340381882	0.828226707	0.830325033	0.990943363	33	3687822	3693837	-	ENSGALG00000047859	protein_coding	--	--	--	ko:K17356|TSPAN13_31	--	1029	XP_025001169.1	XP_025001169.1 LOW QUALITY PROTEIN: tetraspanin-31-like [Gallus gallus]	_	_	_	_	_	_	_	_
ENSGALG00000047947	17.3319432	6.375999639	1.441281188	1.33E-29	2.03E-28	up	yes	18.45402199	15.60013811	17.94166949	7.489455906	5.809988737	5.828554276	22	10948	14283	-	ENSGALG00000047947	protein_coding	GO:0006556|S-adenosylmethionine biosynthetic process; GO:0006730|one-carbon metabolic process; GO:0032259|methylation; GO:0034214|protein hexamerization; GO:0051291|protein heterooligomerization; GO:1990830|cellular response to leukemia inhibitory factor	GO:0005829|cytosol; GO:0048269|methionine adenosyltransferase complex	GO:0004478|methionine adenosyltransferase activity; GO:0005524|ATP binding; GO:0042802|identical protein binding; GO:0046872|metal ion binding	ko:K00789|metK	ko00270|Cysteine and methionine metabolism; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko01230|Biosynthesis of amino acids	1605	XP_014814182.1	"XP_014814182.1 PREDICTED: S-adenosylmethionine synthase isoform type-2, partial [Calidris pugnax]"	sp|P31153|METK2_HUMAN	sp|P31153|METK2_HUMAN S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens GN=MAT2A PE=1 SV=1	_	_	_	_	_	"PF02773.13|S-AdoMet_synt_C|S-adenosylmethionine synthetase, C-terminal domain|ENSGALT00000096602|m.4430:64-174;PF02772.13|S-AdoMet_synt_M|S-adenosylmethionine synthetase, central domain|ENSGALT00000096602|m.4430:8-62"
ENSGALG00000047979	2.751149846	1.25393573	1.127346079	1.54E-12	8.46E-12	up	yes	2.940993654	2.374988871	2.937467013	1.369273776	1.049277196	1.343256218	4	91093743	91112944	-	EBF4	protein_coding	"GO:0007275|multicellular organism development; GO:0045893|positive regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II"	GO:0005634|nucleus	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0046872|metal ion binding"	"ko:K09103|EBF,COE"	--	5124	XP_025005949.1	XP_025005949.1 transcription factor COE4 isoform X2 [Gallus gallus]	sp|O08791|COE3_MOUSE	sp|O08791|COE3_MOUSE Transcription factor COE3 OS=Mus musculus GN=Ebf3 PE=1 SV=1	13616.ENSMODP00000006483	early B-cell factor 4	_	KOG3836	_	PF16422.2|COE1_DBD|Transcription factor COE1 DNA-binding domain|ENSGALT00000103430|m.1899:436-547;PF16423.2|COE1_HLH|Transcription factor COE1 helix-loop-helix domain|ENSGALT00000103430|m.1899:639-682;PF01833.21|TIG|IPT/TIG domain|ENSGALT00000103430|m.1899:554-636;PF16422.2|COE1_DBD|Transcription factor COE1 DNA-binding domain|ENSGALT00000103430|m.1907:1-53
ENSGALG00000048025	0.556532672	0.212684608	1.347157317	0.002090907	0.00418216	up	yes	0.661948356	0.452985035	0.554664626	0.248990675	0.191985314	0.197077835	2	131187964	131207918	+	ENSGALG00000048025	protein_coding	GO:0007158|neuron cell-cell adhesion; GO:0007165|signal transduction; GO:0007268|chemical synaptic transmission; GO:0007269|neurotransmitter secretion; GO:0007416|synapse assembly; GO:0030534|adult behavior; GO:0035176|social behavior; GO:0042297|vocal learning; GO:0071625|vocalization behavior; GO:0097104|postsynaptic membrane assembly; GO:0097116|gephyrin clustering involved in postsynaptic density assembly; GO:0097118|neuroligin clustering involved in postsynaptic membrane assembly; GO:0097119|postsynaptic density protein 95 clustering	GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0032991|protein-containing complex; GO:0098793|presynapse	GO:0004888|transmembrane signaling receptor activity; GO:0005246|calcium channel regulator activity; GO:0046872|metal ion binding; GO:0050839|cell adhesion molecule binding; GO:0097109|neuroligin family protein binding	ko:K07377|NRXN	ko04514|Cell adhesion molecules (CAMs)	2319	XP_025003522.1	"XP_025003522.1 nascent polypeptide-associated complex subunit alpha, muscle-specific form-like [Gallus gallus]"	sp|Q9P2S2|NRX2A_HUMAN	sp|Q9P2S2|NRX2A_HUMAN Neurexin-2 OS=Homo sapiens GN=NRXN2 PE=2 SV=1	9615.ENSCAFP00000021159	neurexin 2	_	KOG3514	_	PF02210.21|Laminin_G_2|Laminin G domain|ENSGALT00000090714|m.2373:139-253;PF00054.20|Laminin_G_1|Laminin G domain|ENSGALT00000090714|m.2373:139-255
ENSGALG00000048038	0.717402382	1.452712123	-1.007820304	0.008378787	0.015018674	down	yes	0.765568572	0.854175825	0.532462751	2.10341282	1.053146338	1.201577213	1	171562969	171579572	-	ENSGALG00000048038	protein_coding	--	--	GO:0016491|oxidoreductase activity	ko:K11168|DHRS12	--	1583	XP_015707348.1	XP_015707348.1 PREDICTED: dehydrogenase/reductase SDR family member 12 isoform X1 [Coturnix japonica]	sp|A0PJE2|DHR12_HUMAN	sp|A0PJE2|DHR12_HUMAN Dehydrogenase/reductase SDR family member 12 OS=Homo sapiens GN=DHRS12 PE=2 SV=2	9031.ENSGALP00000027441	dehydrogenase/reductase (SDR family) member 12	COG1028	KOG1208	_	PF00106.22|adh_short|short chain dehydrogenase|ENSGALT00000099964|m.4340:57-162;PF13561.3|adh_short_C2|Enoyl-(Acyl carrier protein) reductase|ENSGALT00000099964|m.4340:61-160;PF08659.7|KR|KR domain|ENSGALT00000099964|m.4340:56-144
ENSGALG00000048048	0.334537499	0.045779409	2.626856468	2.96E-12	1.59E-11	up	yes	0.366546707	0.171702899	0.46536289	0.030639084	0.042282299	0.064416842	9	15127190	15142216	+	ENSGALG00000048048	protein_coding	GO:0002223|stimulatory C-type lectin receptor signaling pathway; GO:0007160|cell-matrix adhesion; GO:0016266|O-glycan processing; GO:0030277|maintenance of gastrointestinal epithelium	GO:0005615|extracellular space; GO:0005796|Golgi lumen; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0016020|membrane; GO:0031012|extracellular matrix; GO:0031982|vesicle; GO:0070062|extracellular exosome	"GO:0005176|ErbB-2 class receptor binding; GO:0030197|extracellular matrix constituent, lubricant activity"	--	--	10350	XP_025009390.1	XP_025009390.1 mucin-4 isoform X4 [Gallus gallus]	sp|Q99102|MUC4_HUMAN	sp|Q99102|MUC4_HUMAN Mucin-4 OS=Homo sapiens GN=MUC4 PE=1 SV=4	9031.ENSGALP00000012104	"mucin 12, cell surface associated"	_	KOG4291	_	PF06119.11|NIDO|Nidogen-like|ENSGALT00000097228|m.8980:2264-2347;PF00094.22|VWD|von Willebrand factor type D domain|ENSGALT00000097228|m.8980:2501-2666
ENSGALG00000048064	17.46272871	8.129456412	1.102100577	4.24E-09	1.73E-08	up	yes	16.69096611	17.99681008	17.70040993	6.852759496	9.578235114	7.957374627	2	131158698	131165907	+	ENSGALG00000048064	protein_coding	GO:0005980|glycogen catabolic process	GO:0005737|cytoplasm	GO:0000166|nucleotide binding; GO:0008184|glycogen phosphorylase activity; GO:0030170|pyridoxal phosphate binding; GO:0102250|linear malto-oligosaccharide phosphorylase activity; GO:0102499|SHG alpha-glucan phosphorylase activity	"ko:K00688|PYG,glgP"	ko00500|Starch and sucrose metabolism; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko02026|Biofilm formation - Escherichia coli; ko04910|Insulin signaling pathway; ko04922|Glucagon signaling pathway; ko04931|Insulin resistance	483	XP_025003894.1	"XP_025003894.1 glycogen phosphorylase, muscle form-like [Gallus gallus]"	sp|P79334|PYGM_BOVIN	"sp|P79334|PYGM_BOVIN Glycogen phosphorylase, muscle form OS=Bos taurus GN=PYGM PE=1 SV=3"	28377.ENSACAP00000005124	annotation not avaliable	COG0058	KOG2099	_	PF00343.17|Phosphorylase|Carbohydrate phosphorylase|ENSGALT00000092695|m.2370:1-144
ENSGALG00000048205	15.34099151	4.390951474	1.802444472	2.83E-30	4.51E-29	up	yes	17.9763772	15.03207242	13.0145249	4.48922698	4.42635723	4.257270213	30	304787	306703	+	ENSGALG00000048205	protein_coding	GO:0001501|skeletal system development; GO:0006695|cholesterol biosynthetic process; GO:0008203|cholesterol metabolic process; GO:0030097|hemopoiesis; GO:0033489|cholesterol biosynthetic process via desmosterol; GO:0033490|cholesterol biosynthetic process via lathosterol	GO:0005635|nuclear envelope; GO:0005783|endoplasmic reticulum; GO:0005789|endoplasmic reticulum membrane; GO:0005887|integral component of plasma membrane; GO:0031410|cytoplasmic vesicle	GO:0000247|C-8 sterol isomerase activity; GO:0004769|steroid delta-isomerase activity; GO:0004888|transmembrane signaling receptor activity; GO:0042910|xenobiotic transmembrane transporter activity; GO:0047750|cholestenol delta-isomerase activity	ko:K01824|EBP	ko00100|Steroid biosynthesis; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites	1064	XP_015130063.1	"XP_015130063.1 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase [Gallus gallus]"	sp|Q15125|EBP_HUMAN	"sp|Q15125|EBP_HUMAN 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase OS=Homo sapiens GN=EBP PE=1 SV=3"	28377.ENSACAP00000016381	emopamil binding protein (sterol isomerase)	_	KOG4826	_	PF05241.9|EBP|Emopamil binding protein|ENSGALT00000093176|m.13480:40-206
ENSGALG00000048212	52.10600777	18.438972	1.498186144	4.15E-20	3.93E-19	up	yes	47.69219091	51.60992909	57.01590332	23.63113034	14.64082688	17.04495878	1	48140188	48140577	+	H2A-VII	protein_coding	GO:0006342|chromatin silencing	GO:0000786|nucleosome; GO:0000790|nuclear chromatin	GO:0003677|DNA binding; GO:0046982|protein heterodimerization activity	ko:K11251|H2A	ko05034|Alcoholism; ko05322|Systemic lupus erythematosus	390	EOB06730.1	"EOB06730.1 Histone H2A-IV, partial [Anas platyrhynchos]"	sp|P02263|H2A4_CHICK	sp|P02263|H2A4_CHICK Histone H2A-IV OS=Gallus gallus PE=1 SV=2	9031.ENSGALP00000019162	Histone H2A-IV 	COG5262	KOG1756	_	PF16211.2|Histone_H2A_C|C-terminus of histone H2A|ENSGALT00000093393|m.1199:92-125;PF00125.21|Histone|Core histone H2A/H2B/H3/H4|ENSGALT00000093393|m.1199:5-89;PF00808.20|CBFD_NFYB_HMF|Histone-like transcription factor (CBF/NF-Y) and archaeal histone|ENSGALT00000093393|m.1199:25-88
ENSGALG00000048231	55.44035797	14.77699604	1.906867774	8.93E-31	1.46E-29	up	yes	58.07557996	54.14281198	54.10268198	18.46941338	10.54632529	15.31524945	1	48076386	48076796	-	ENSGALG00000048231	protein_coding	GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006334|nucleosome assembly	GO:0000786|nucleosome; GO:0005634|nucleus	GO:0031492|nucleosomal DNA binding; GO:0046982|protein heterodimerization activity	ko:K11253|H3	ko05034|Alcoholism; ko05202|Transcriptional misregulation in cancer; ko05322|Systemic lupus erythematosus	411	EOB06698.1	"EOB06698.1 Histone H3, partial [Anas platyrhynchos]"	sp|P84227|H32_BOVIN	sp|P84227|H32_BOVIN Histone H3.2 OS=Bos taurus PE=1 SV=2	_	_	_	_	_	PF00125.21|Histone|Core histone H2A/H2B/H3/H4|ENSGALT00000102489|m.1166:1-132
ENSGALG00000048236	0.256424478	0.11222993	1.124129042	0.007373228	0.013370962	up	yes	0.23446682	0.234424468	0.300382145	0.096211931	0.109590911	0.130886948	33	6270021	6279764	-	ENSGALG00000048236	protein_coding	GO:0007159|leukocyte cell-cell adhesion; GO:0007229|integrin-mediated signaling pathway; GO:0030335|positive regulation of cell migration; GO:0033622|integrin activation; GO:0033632|regulation of cell-cell adhesion mediated by integrin; GO:0034446|substrate adhesion-dependent cell spreading; GO:0070527|platelet aggregation	GO:0002102|podosome; GO:0030054|cell junction; GO:0042995|cell projection	GO:0005178|integrin binding	"ko:K17084|FERMT3,KIND3"	ko04611|Platelet activation	1922	XP_025001277.1	XP_025001277.1 LOW QUALITY PROTEIN: fermitin family homolog 3 [Gallus gallus]	sp|Q32LP0|URP2_BOVIN	sp|Q32LP0|URP2_BOVIN Fermitin family homolog 3 OS=Bos taurus GN=FERMT3 PE=2 SV=1	_	_	_	_	_	PF00373.15|FERM_M|FERM central domain|ENSGALT00000094443|m.15306:89-198
ENSGALG00000048303	1.475175082	0.401011613	1.853381952	0.000249985	0.000577215	up	yes	1.065662476	1.736321451	1.623541319	0.200423505	0.561954152	0.440657182	10	11274948	11277738	+	ENSGALG00000048303	protein_coding	GO:0006511|ubiquitin-dependent protein catabolic process; GO:0016579|protein deubiquitination	--	GO:0036459|thiol-dependent ubiquitinyl hydrolase activity	--	--	890	XP_004943871.1	XP_004943871.1 inactive ubiquitin carboxyl-terminal hydrolase 50 [Gallus gallus]	sp|Q4R6D3|UBP50_MACFA	sp|Q4R6D3|UBP50_MACFA Putative ubiquitin carboxyl-terminal hydrolase 50 OS=Macaca fascicularis GN=USP50 PE=2 SV=1	13616.ENSMODP00000002684	ubiquitin specific peptidase 50	COG5533	KOG1868	_	PF00443.26|UCH|Ubiquitin carboxyl-terminal hydrolase|ENSGALT00000100221|m.5566:14-113
ENSGALG00000048349	33.52738505	15.15814064	1.144725959	5.70E-23	6.36E-22	up	yes	34.79092346	32.31764336	33.47358834	16.32653795	15.64931072	13.49857324	10	20508515	20509940	+	PRC1	protein_coding	GO:0000022|mitotic spindle elongation; GO:0000910|cytokinesis; GO:0001578|microtubule bundle formation; GO:0008284|positive regulation of cell population proliferation	GO:0000922|spindle pole; GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005819|spindle; GO:0005829|cytosol; GO:0005876|spindle microtubule; GO:0005886|plasma membrane; GO:0015630|microtubule cytoskeleton; GO:0030496|midbody; GO:0070938|contractile ring	GO:0008017|microtubule binding; GO:0019894|kinesin binding; GO:0019901|protein kinase binding; GO:0042802|identical protein binding	ko:K16732|PRC1	--	783	NP_001073221.1	NP_001073221.1 protein regulator of cytokinesis 1 [Gallus gallus]	sp|O43663|PRC1_HUMAN	sp|O43663|PRC1_HUMAN Protein regulator of cytokinesis 1 OS=Homo sapiens GN=PRC1 PE=1 SV=2	9031.ENSGALP00000028134	Putative uncharacterized protein 	_	KOG4302	_	PF03999.9|MAP65_ASE1|Microtubule associated protein (MAP65/ASE1 family)|ENSGALT00000020937|m.6016:36-259
ENSGALG00000048409	8.728727745	23.25642772	-1.412754558	3.84E-55	1.62E-53	down	yes	9.247929981	9.021713669	7.916539587	20.98408094	24.30632045	24.47888176	25	1948755	1958413	+	TXNIP	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006351|transcription, DNA-templated; GO:0006606|protein import into nucleus; GO:0006979|response to oxidative stress; GO:0007049|cell cycle; GO:0030216|keratinocyte differentiation; GO:0048008|platelet-derived growth factor receptor signaling pathway; GO:0051782|negative regulation of cell division; GO:0071228|cellular response to tumor cell"	GO:0005737|cytoplasm	GO:0004857|enzyme inhibitor activity; GO:0031625|ubiquitin protein ligase binding	ko:K20910|TXNIP	ko04621|NOD-like receptor signaling pathway	3416	XP_010725610.2	"XP_010725610.2 PREDICTED: thioredoxin-interacting protein, partial [Meleagris gallopavo]"	sp|Q2HY40|TXNIP_PIG	sp|Q2HY40|TXNIP_PIG Thioredoxin-interacting protein OS=Sus scrofa GN=TXNIP PE=2 SV=1	_	_	_	_	_	"PF02752.19|Arrestin_C|Arrestin (or S-antigen), C-terminal domain|ENSGALT00000091357|m.6773:111-218"
ENSGALG00000048467	1.286534478	0.541056624	1.234388095	0.000291721	0.000667329	up	yes	1.288564646	1.376087828	1.194950962	0.558448622	0.37667758	0.688043671	31	2778667	2783924	-	SYP	protein_coding	GO:0006897|endocytosis; GO:0016188|synaptic vesicle maturation; GO:0048168|regulation of neuronal synaptic plasticity; GO:0048169|regulation of long-term neuronal synaptic plasticity; GO:0048172|regulation of short-term neuronal synaptic plasticity; GO:0048488|synaptic vesicle endocytosis; GO:0048499|synaptic vesicle membrane organization; GO:0071310|cellular response to organic substance; GO:2000474|regulation of opioid receptor signaling pathway	GO:0008021|synaptic vesicle; GO:0030054|cell junction; GO:0030285|integral component of synaptic vesicle membrane; GO:0031594|neuromuscular junction; GO:0042734|presynaptic membrane; GO:0043005|neuron projection; GO:0043195|terminal bouton; GO:0048786|presynaptic active zone; GO:0060076|excitatory synapse	GO:0005215|transporter activity; GO:0015485|cholesterol binding; GO:0042169|SH2 domain binding; GO:0042802|identical protein binding; GO:0043621|protein self-association	--	--	1573	XP_014117715.1	XP_014117715.1 PREDICTED: synaptophysin-like [Pseudopodoces humilis]	sp|P08247|SYPH_HUMAN	sp|P08247|SYPH_HUMAN Synaptophysin OS=Homo sapiens GN=SYP PE=1 SV=3	28377.ENSACAP00000012707	synaptophysin	_	_	NOG82723	PF01284.20|MARVEL|Membrane-associating domain|ENSGALT00000097988|m.14064:195-321
ENSGALG00000048534	2.911149331	0.942090509	1.617365479	5.15E-10	2.29E-09	up	yes	2.539698255	2.557595448	3.636154289	1.127947999	0.798712421	0.899611106	11	1248882	1255087	-	ENSGALG00000048534	protein_coding	GO:0035023|regulation of Rho protein signal transduction; GO:0090630|activation of GTPase activity	--	GO:0005089|Rho guanyl-nucleotide exchange factor activity	--	--	1722	XP_004944157.2	XP_004944157.2 puratrophin-1 isoform X2 [Gallus gallus]	sp|Q58EX7|PKHG4_HUMAN	sp|Q58EX7|PKHG4_HUMAN Puratrophin-1 OS=Homo sapiens GN=PLEKHG4 PE=1 SV=1	_	_	_	_	_	PF00621.17|RhoGEF|RhoGEF domain|ENSGALT00000040176|m.6282:103-266;PF00169.26|PH|PH domain|ENSGALT00000040176|m.6282:308-393
ENSGALG00000048539	2.575546118	6.748830401	-1.386304575	2.78E-11	1.38E-10	down	yes	2.270861753	2.185309625	3.270466978	7.367307106	5.444837484	7.434346612	1	67588709	67590637	-	BHLHE41	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006351|transcription, DNA-templated; GO:0007623|circadian rhythm; GO:0010832|negative regulation of myotube differentiation; GO:0010944|negative regulation of transcription by competitive promoter binding; GO:0032922|circadian regulation of gene expression; GO:0045892|negative regulation of transcription, DNA-templated"	GO:0005654|nucleoplasm; GO:0017053|transcriptional repressor complex	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0001102|RNA polymerase II activating transcription factor binding; GO:0001227|DNA-binding transcription repressor activity, RNA polymerase II-specific; GO:0003714|transcription corepressor activity; GO:0042803|protein homodimerization activity; GO:0042826|histone deacetylase binding; GO:0043425|bHLH transcription factor binding; GO:0043426|MRF binding; GO:0046982|protein heterodimerization activity; GO:0070888|E-box binding"	"ko:K03730|BHLHB3,DEC2"	ko04710|Circadian rhythm	1485	XP_015146971.2	XP_015146971.2 class E basic helix-loop-helix protein 41 [Gallus gallus]	sp|Q99PV5|BHE41_MOUSE	sp|Q99PV5|BHE41_MOUSE Class E basic helix-loop-helix protein 41 OS=Mus musculus GN=Bhlhe41 PE=1 SV=1	_	_	_	_	_	PF00010.23|HLH|Helix-loop-helix DNA-binding domain|ENSGALT00000104406|m.2020:103-153;PF07527.10|Hairy_orange|Hairy Orange|ENSGALT00000104406|m.2020:185-224
ENSGALG00000048543	1.338040647	3.483567292	-1.373836931	0.003475856	0.006689832	down	yes	1.691318909	1.430857492	0.891945539	3.768181835	4.116371981	2.566148061	12	12187651	12189390	+	RPP14	protein_coding	GO:0001682|tRNA 5'-leader removal	GO:0005634|nucleus; GO:0030681|multimeric ribonuclease P complex	GO:0004526|ribonuclease P activity	ko:K14529|RPP14	ko03013|RNA transport	405	POI20011.1	POI20011.1 hypothetical protein CIB84_016243 [Bambusicola thoracicus]	sp|Q9CQH8|RPP14_MOUSE	sp|Q9CQH8|RPP14_MOUSE Ribonuclease P protein subunit p14 OS=Mus musculus GN=Rpp14 PE=1 SV=1	9823.ENSSSCP00000012226	ribonuclease P/MRP 14kDa subunit	_	_	NOG77977	PF01900.16|RNase_P_Rpp14|Rpp14/Pop5 family|ENSGALT00000094928|m.7921:21-109
ENSGALG00000048601	0.400052507	0.107722702	1.8004161	0.000103989	0.000254506	up	yes	0.200946676	0.452526709	0.546684136	0.09178267	0.119210514	0.112174922	4	66168833	66177082	+	ENSGALG00000048601	protein_coding	--	--	--	--	--	3671	XP_004936089.1	XP_004936089.1 leucine-rich repeat-containing protein 66 [Gallus gallus]	_	_	_	_	_	_	_	PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000108035|m.1116:90-127;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000108035|m.1116:197-248;PF00047.22|ig|Immunoglobulin domain|ENSGALT00000108035|m.1116:315-383
ENSGALG00000048671	1.206923921	0.443916619	1.422739763	0.000479806	0.001061618	up	yes	1.539362311	1.128661783	0.95274767	0.361892715	0.659546515	0.310310627	13	9077075	9083870	-	ENSGALG00000048671	protein_coding	--	--	--	--	--	1643	XP_414478.5	XP_414478.5 E3 ubiquitin/ISG15 ligase TRIM25 isoform X2 [Gallus gallus]	_	_	9031.ENSGALP00000001835	similar to Zinc finger protein 147 (Tripartite motif protein 25) (Estrogen responsive finger [...] 	_	KOG2177	_	"PF13445.3|zf-RING_UBOX|RING-type zinc-finger|ENSGALT00000096240|m.8536:37-78;PF15227.3|zf-C3HC4_4|zinc finger of C3HC4-type, RING|ENSGALT00000096240|m.8536:37-80;PF13639.3|zf-RING_2|Ring finger domain|ENSGALT00000096240|m.8536:36-81;PF00097.22|zf-C3HC4|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000096240|m.8536:37-80;PF00643.21|zf-B_box|B-box zinc finger|ENSGALT00000096240|m.8536:174-213;PF13920.3|zf-C3HC4_3|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000096240|m.8536:34-82;PF13923.3|zf-C3HC4_2|Zinc finger, C3HC4 type (RING finger)|ENSGALT00000096240|m.8536:37-80"
ENSGALG00000048700	4.713229333	2.195772471	1.098489604	9.94E-09	3.91E-08	up	yes	4.84204643	4.211719229	5.085922339	2.579270523	2.105323384	1.902723507	11	3423355	3425106	+	DDX28	protein_coding	GO:0010501|RNA secondary structure unwinding; GO:1902775|mitochondrial large ribosomal subunit assembly	GO:0005634|nucleus; GO:0005730|nucleolus; GO:0005739|mitochondrion; GO:0005829|cytosol; GO:0035770|ribonucleoprotein granule; GO:0042645|mitochondrial nucleoid	GO:0003723|RNA binding; GO:0003724|RNA helicase activity; GO:0005524|ATP binding; GO:0019843|rRNA binding	ko:K20096|DDX28	--	1752	XP_015147851.2	XP_015147851.2 probable ATP-dependent RNA helicase DDX28 [Gallus gallus]	sp|Q9NUL7|DDX28_HUMAN	sp|Q9NUL7|DDX28_HUMAN Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens GN=DDX28 PE=1 SV=2	28377.ENSACAP00000009540	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28	COG0513	KOG0330	_	PF00270.26|DEAD|DEAD/DEAH box helicase|ENSGALT00000106471|m.6442:188-382;PF00271.28|Helicase_C|Helicase conserved C-terminal domain|ENSGALT00000106471|m.6442:425-535
ENSGALG00000048716	4.150547766	11.53629986	-1.472585211	2.37E-26	3.17E-25	down	yes	2.972401142	4.406370638	5.072871517	11.44334737	11.40242335	11.76312886	1	155810119	155824758	+	FBXL3	protein_coding	GO:0000209|protein polyubiquitination; GO:0016567|protein ubiquitination; GO:0031146|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0031648|protein destabilization; GO:0042752|regulation of circadian rhythm; GO:0043153|entrainment of circadian clock by photoperiod; GO:0043687|post-translational protein modification; GO:0048511|rhythmic process	GO:0000151|ubiquitin ligase complex; GO:0005634|nucleus; GO:0005829|cytosol; GO:0016604|nuclear body; GO:0019005|SCF ubiquitin ligase complex	GO:0004842|ubiquitin-protein transferase activity	ko:K10269|FBXL3	ko04710|Circadian rhythm	3244	XP_425611.4	XP_425611.4 F-box/LRR-repeat protein 3 [Gallus gallus]	sp|Q9UKT7|FBXL3_HUMAN	sp|Q9UKT7|FBXL3_HUMAN F-box/LRR-repeat protein 3 OS=Homo sapiens GN=FBXL3 PE=1 SV=1	9031.ENSGALP00000027297	F-box and leucine-rich repeat protein 3	_	KOG1947	_	PF12937.4|F-box-like|F-box-like|ENSGALT00000105171|m.4086:47-82;PF00646.30|F-box|F-box domain|ENSGALT00000105171|m.4086:43-84
ENSGALG00000048723	2.746716222	5.776101659	-1.069640908	0.006262855	0.011502368	down	yes	2.968512062	2.539268226	2.732368378	7.304427839	2.935089177	7.08878796	30	1211156	1212606	+	ENSGALG00000048723	protein_coding	GO:0008216|spermidine metabolic process; GO:0008612|peptidyl-lysine modification to peptidyl-hypusine; GO:0042102|positive regulation of T cell proliferation; GO:0042593|glucose homeostasis	GO:0005737|cytoplasm	GO:0034038|deoxyhypusine synthase activity; GO:0042802|identical protein binding	"ko:K00809|DHPS,dys"	--	426	XP_025001593.1	XP_025001593.1 LOW QUALITY PROTEIN: deoxyhypusine synthase [Gallus gallus]	sp|Q6EWQ6|DHYS_BOVIN	sp|Q6EWQ6|DHYS_BOVIN Deoxyhypusine synthase OS=Bos taurus GN=DHPS PE=2 SV=2	_	_	_	_	_	PF01916.14|DS|Deoxyhypusine synthase|ENSGALT00000101436|m.13814:54-133
ENSGALG00000048773	2.736190671	1.346604039	1.017432103	2.68E-07	9.12E-07	up	yes	3.002895197	2.819475649	2.386201166	1.373317815	1.315796025	1.350698276	33	7754178	7761485	+	ENSGALG00000048773	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated"	GO:0005634|nucleus	GO:0003677|DNA binding; GO:0046872|metal ion binding	--	--	2439	XP_025001294.1	XP_025001294.1 zinc finger protein 646-like [Gallus gallus]	sp|O15015|ZN646_HUMAN	sp|O15015|ZN646_HUMAN Zinc finger protein 646 OS=Homo sapiens GN=ZNF646 PE=1 SV=1	9796.ENSECAP00000006158	zinc finger protein 646	_	KOG1721	_	PF13912.3|zf-C2H2_6|C2H2-type zinc finger|ENSGALT00000104270|m.15848:108-133;PF13912.3|zf-C2H2_6|C2H2-type zinc finger|ENSGALT00000104270|m.15848:175-199;PF13912.3|zf-C2H2_6|C2H2-type zinc finger|ENSGALT00000104270|m.15848:519-541
ENSGALG00000048865	5.091086492	1.997492561	1.345409921	2.35E-11	1.17E-10	up	yes	4.936764625	4.707897922	5.628596928	1.553531039	2.169413739	2.269532904	10	519307	530171	-	ENSGALG00000048865	protein_coding	--	--	--	--	--	1633	XP_025009716.1	XP_025009716.1 armadillo repeat-containing protein 5 [Gallus gallus]	_	_	_	_	_	_	_	_
ENSGALG00000048869	1.869125719	0.784458059	1.242018626	2.13E-07	7.35E-07	up	yes	1.90091866	1.655084315	2.051374183	0.662889716	0.924095345	0.766389117	2	15866607	15871487	+	ENSGALG00000048869	protein_coding	--	GO:0016021|integral component of membrane; GO:0097225|sperm midpiece	--	--	--	2661	XP_004949891.2	XP_004949891.2 patched domain-containing protein 3 [Gallus gallus]	sp|Q0EEE2|PTHD3_MOUSE	sp|Q0EEE2|PTHD3_MOUSE Patched domain-containing protein 3 OS=Mus musculus GN=Ptchd3 PE=1 SV=1	59729.ENSTGUP00000001144	Patched domain-containing protein 3 (Patched-related protein) [Taeniopygia guttata]	_	KOG1934	_	PF02460.15|Patched|Patched family|ENSGALT00000077652|m.14917:64-849;PF12349.5|Sterol-sensing|Sterol-sensing domain of SREBP cleavage-activation|ENSGALT00000077652|m.14917:296-447
ENSGALG00000048879	0.274541584	1.249774354	-2.146453933	0.000294602	0.000672908	down	yes	0	0.207545715	0.616079037	1.140809154	1.35942158	1.249092328	8	17017299	17020087	-	SAMD13	protein_coding	--	--	--	--	--	1303	OXB55474.1	OXB55474.1 hypothetical protein ASZ78_012906 [Callipepla squamata]	sp|Q5VXD3|SAM13_HUMAN	sp|Q5VXD3|SAM13_HUMAN Sterile alpha motif domain-containing protein 13 OS=Homo sapiens GN=SAMD13 PE=2 SV=1	_	_	_	_	_	_
ENSGALG00000048954	0.211414641	1.002472922	-2.193060796	1.28E-05	3.56E-05	down	yes	0.187179713	0.11436694	0.33269727	0.844887717	0.838994112	1.323536937	4	45674817	45677051	-	DMP1	protein_coding	--	--	--	--	--	1689	NP_996876.1	NP_996876.1 dentin matrix acidic phosphoprotein 1 precursor [Gallus gallus]	_	_	9031.ENSGALP00000031553	dentin matrix acidic phosphoprotein 	_	_	NOG86154	_
ENSGALG00000049027	2.244611182	0.595227003	1.897330393	3.74E-12	1.99E-11	up	yes	1.878045847	2.075174345	2.780613353	0.646725778	0.617223321	0.52173191	8	24835193	24837184	-	ENSGALG00000049027	protein_coding	GO:0046797|viral procapsid maturation	GO:0019028|viral capsid; GO:0044095|host cell nucleoplasm; GO:0044196|host cell nucleolus	GO:0003676|nucleic acid binding; GO:0004190|aspartic-type endopeptidase activity; GO:0008270|zinc ion binding; GO:0039660|structural constituent of virion	--	--	1992	XP_015146692.1	XP_015146692.1 uncharacterized protein LOC107054036 [Gallus gallus]	sp|O92954|GAG_RSVSB	sp|O92954|GAG_RSVSB Gag-Pro polyprotein OS=Rous sarcoma virus (strain Schmidt-Ruppin B) GN=gag-pro PE=1 SV=1	_	_	_	_	_	PF02813.11|Retro_M|Retroviral M domain|ENSGALT00000098403|m.7990:3-87;PF00077.17|RVP|Retroviral aspartyl protease|ENSGALT00000098403|m.7990:547-660;PF00607.17|Gag_p24|gag gene protein p24 (core nucleocapsid protein)|ENSGALT00000098403|m.7990:232-384;PF00098.20|zf-CCHC|Zinc knuckle|ENSGALT00000098403|m.7990:467-482
ENSGALG00000049137	0.181169339	0.649990055	-1.787593131	9.74E-06	2.75E-05	down	yes	0.127119636	0.186408455	0.229979926	0.788961042	0.534175609	0.626833513	3	16929944	16971787	+	SHLD1	protein_coding	--	--	--	--	--	3159	XP_021245558.1	XP_021245558.1 uncharacterized protein C20orf196 homolog [Numida meleagris]	_	_	9031.ENSGALP00000031324	annotation not avaliable	_	_	NOG44092	PF15021.3|DUF4521|Protein of unknown function (DUF4521)|ENSGALT00000093322|m.11051:1-217
ENSGALG00000049176	1.989719502	4.497783375	-1.172620538	4.28E-10	1.92E-09	down	yes	1.907780812	2.331310914	1.730066779	3.963931541	5.218765674	4.310652912	1	42836699	42851268	-	ENSGALG00000049176	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0007163|establishment or maintenance of cell polarity; GO:0007368|determination of left/right symmetry; GO:0007507|heart development; GO:0015031|protein transport; GO:0030902|hindbrain development; GO:0030916|otic vesicle formation; GO:0042462|eye photoreceptor cell development; GO:0045494|photoreceptor cell maintenance; GO:0045893|positive regulation of transcription, DNA-templated; GO:0048793|pronephros development; GO:0060041|retina development in camera-type eye; GO:0060271|cilium assembly; GO:0070201|regulation of establishment of protein localization; GO:0090316|positive regulation of intracellular protein transport; GO:1905515|non-motile cilium assembly"	GO:0001750|photoreceptor outer segment; GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005813|centrosome; GO:0005814|centriole; GO:0005829|cytosol; GO:0016020|membrane; GO:0031410|cytoplasmic vesicle; GO:0032391|photoreceptor connecting cilium; GO:0032991|protein-containing complex; GO:0034451|centriolar satellite; GO:0035869|ciliary transition zone; GO:0036038|MKS complex	GO:0042802|identical protein binding	"ko:K16533|CEP290,NPHP6"	--	2320	XP_004937659.1	XP_004937659.1 centrosomal protein of 290 kDa [Gallus gallus]	sp|Q6A078|CE290_MOUSE	sp|Q6A078|CE290_MOUSE Centrosomal protein of 290 kDa OS=Mus musculus GN=Cep290 PE=1 SV=2	9031.ENSGALP00000018199	centrosomal protein 290kDa	_	_	NOG136455	_
ENSGALG00000049232	0.747942	0.084258063	3.007399521	9.44E-07	3.03E-06	up	yes	0.800988136	1.097967977	0.344869888	0.078597453	0.096413703	0.077763032	33	6187895	6195357	+	ENSGALG00000049232	protein_coding	GO:0006366|transcription by RNA polymerase II; GO:0033120|positive regulation of RNA splicing	"GO:0005634|nucleus; GO:0005665|RNA polymerase II, core complex; GO:0005737|cytoplasm"	GO:0003677|DNA binding; GO:0003899|DNA-directed 5'-3' RNA polymerase activity; GO:0046872|metal ion binding	"ko:K03006|RPB1,POLR2A"	ko00230|Purine metabolism; ko00240|Pyrimidine metabolism; ko01100|Metabolic pathways; ko03020|RNA polymerase; ko05016|Huntington's disease; ko05168|Herpes simplex infection; ko05169|Epstein-Barr virus infection	1513	XP_025001275.1	"XP_025001275.1 LOW QUALITY PROTEIN: DNA-directed RNA polymerase II subunit RPB1-like, partial [Gallus gallus]"	sp|P11414|RPB1_CRIGR	sp|P11414|RPB1_CRIGR DNA-directed RNA polymerase II subunit RPB1 OS=Cricetulus griseus GN=POLR2A PE=2 SV=2	9685.ENSFCAP00000008916	"polymerase (RNA) II (DNA directed) polypeptide A, 220kDa"	COG0086	KOG0260	_	"PF04997.9|RNA_pol_Rpb1_1|RNA polymerase Rpb1, domain 1|ENSGALT00000100721|m.15283:39-120;PF04997.9|RNA_pol_Rpb1_1|RNA polymerase Rpb1, domain 1|ENSGALT00000100721|m.15284:22-51;PF04997.9|RNA_pol_Rpb1_1|RNA polymerase Rpb1, domain 1|ENSGALT00000100721|m.15285:22-51"
ENSGALG00000049268	65.25056772	23.11882683	1.496519448	3.74E-28	5.39E-27	up	yes	64.71546585	65.47824017	65.55799714	28.15407787	19.98419436	21.21820828	1	48067286	48067675	+	H2A-VII	protein_coding	GO:0006342|chromatin silencing	GO:0000786|nucleosome; GO:0000790|nuclear chromatin	GO:0003677|DNA binding; GO:0046982|protein heterodimerization activity	ko:K11251|H2A	ko05034|Alcoholism; ko05322|Systemic lupus erythematosus	390	EOB06730.1	"EOB06730.1 Histone H2A-IV, partial [Anas platyrhynchos]"	sp|P02263|H2A4_CHICK	sp|P02263|H2A4_CHICK Histone H2A-IV OS=Gallus gallus PE=1 SV=2	9031.ENSGALP00000019162	Histone H2A-IV 	COG5262	KOG1756	_	PF16211.2|Histone_H2A_C|C-terminus of histone H2A|ENSGALT00000094867|m.1161:92-125;PF00125.21|Histone|Core histone H2A/H2B/H3/H4|ENSGALT00000094867|m.1161:5-89;PF00808.20|CBFD_NFYB_HMF|Histone-like transcription factor (CBF/NF-Y) and archaeal histone|ENSGALT00000094867|m.1161:25-88
ENSGALG00000049299	31.00998285	14.94202215	1.052857277	3.72E-34	7.17E-33	up	yes	29.32109245	31.9925816	31.71627451	13.76592054	16.52699596	14.53314997	2	62951146	62972331	-	TMEM170B	protein_coding	--	GO:0016021|integral component of membrane	--	--	--	2426	XP_418945.1	XP_418945.1 transmembrane protein 170B isoform X1 [Gallus gallus]	sp|Q5T4T1|T170B_HUMAN	sp|Q5T4T1|T170B_HUMAN Transmembrane protein 170B OS=Homo sapiens GN=TMEM170B PE=3 SV=1	9031.ENSGALP00000020769	transmembrane protein 170B	_	KOG4349	_	PF10190.6|Tmemb_170|Putative transmembrane protein 170|ENSGALT00000098662|m.925:27-131
ENSGALG00000049343	2.584433308	0.99445247	1.369010152	3.90E-07	1.31E-06	up	yes	2.903957766	2.770504945	2.078837213	1.052837063	0.940943595	0.989576754	KZ626838.1	1607024	1608529	+	ENSGALG00000049343	protein_coding	--	--	--	--	--	1506	XP_025002136.1	XP_025002136.1 uncharacterized protein LOC107049357 [Gallus gallus]	_	_	_	_	_	_	_	PF00607.17|Gag_p24|gag gene protein p24 (core nucleocapsid protein)|ENSGALT00000093232|m.9942:231-412
ENSGALG00000049408	51.68439869	15.7656143	1.712311782	2.45E-64	1.38E-62	up	yes	46.96242828	56.58810599	51.50266179	15.41528932	16.20821468	15.67333889	1	48087185	48088021	+	HIST1H2B8	protein_coding	GO:0006334|nucleosome assembly	GO:0000786|nucleosome; GO:0005634|nucleus	GO:0003677|DNA binding; GO:0046982|protein heterodimerization activity	ko:K11252|H2B	ko05034|Alcoholism; ko05203|Viral carcinogenesis; ko05322|Systemic lupus erythematosus	837	XP_003202247.2	XP_003202247.2 PREDICTED: histone H2B 8-like [Meleagris gallopavo]	sp|Q9PSW9|H2B8_CHICK	sp|Q9PSW9|H2B8_CHICK Histone H2B 8 OS=Gallus gallus GN=H2B-VIII PE=1 SV=3	9031.ENSGALP00000019169	Histone H2B 8 (H2B VIII); Core component of nucleosome. Nucleosomes wrap and compact DNA int [...] 	_	KOG1744	_	PF00125.21|Histone|Core histone H2A/H2B/H3/H4|ENSGALT00000073766|m.1172:10-101;PF00808.20|CBFD_NFYB_HMF|Histone-like transcription factor (CBF/NF-Y) and archaeal histone|ENSGALT00000073766|m.1172:42-99
ENSGALG00000049414	13.20507632	47.53013869	-1.846961355	7.41E-104	1.01E-101	down	yes	13.19597195	13.18616575	13.23309127	44.77748662	53.39339717	44.41953228	6	18418468	18425791	-	CYP2C23a	protein_coding	GO:0019373|epoxygenase P450 pathway; GO:0042493|response to drug	GO:0005623|cell; GO:0005789|endoplasmic reticulum membrane; GO:0031090|organelle membrane	GO:0005506|iron ion binding; GO:0008392|arachidonic acid epoxygenase activity; GO:0008395|steroid hydroxylase activity; GO:0020037|heme binding; GO:0070330|aromatase activity	ko:K17853|CYP2H	--	2839	NP_001001616.1	NP_001001616.1 cytochrome P450 2H1 precursor [Gallus gallus]	sp|P05180|CP2H1_CHICK	sp|P05180|CP2H1_CHICK Cytochrome P450 2H1 OS=Gallus gallus GN=CYP2H1 PE=2 SV=1	_	_	_	_	_	PF00067.19|p450|Cytochrome P450|ENSGALT00000040063|m.4800:33-487
ENSGALG00000049422	21.95731388	46.04479586	-1.067992927	1.60E-52	6.29E-51	down	yes	22.0833596	21.99662467	21.79195738	49.55952104	43.04753919	45.52732736	3	21942839	21967759	-	ATF3	protein_coding	GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006094|gluconeogenesis; GO:0008284|positive regulation of cell population proliferation; GO:0034198|cellular response to amino acid starvation; GO:0035914|skeletal muscle cell differentiation; GO:0036499|PERK-mediated unfolded protein response; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0061394|regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance; GO:0070373|negative regulation of ERK1 and ERK2 cascade; GO:1903984|positive regulation of TRAIL-activated apoptotic signaling pathway; GO:1990440|positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005730|nucleolus; GO:1990622|CHOP-ATF3 complex	"GO:0000976|transcription regulatory region sequence-specific DNA binding; GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding; GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0001227|DNA-binding transcription repressor activity, RNA polymerase II-specific; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003700|DNA-binding transcription factor activity; GO:0003714|transcription corepressor activity; GO:0042802|identical protein binding; GO:0042803|protein homodimerization activity; GO:0044212|transcription regulatory region DNA binding; GO:0046982|protein heterodimerization activity"	"ko:K09032|ATF3,LRF1"	ko05166|HTLV-I infection	3762	PKU48900.1	PKU48900.1 cyclic amp-dependent transcription factor atf-3 [Limosa lapponica baueri]	sp|P18847|ATF3_HUMAN	sp|P18847|ATF3_HUMAN Cyclic AMP-dependent transcription factor ATF-3 OS=Homo sapiens GN=ATF3 PE=1 SV=2	9031.ENSGALP00000015949	activating transcription factor 3	_	KOG1414	_	PF00170.18|bZIP_1|bZIP transcription factor|ENSGALT00000108231|m.11204:85-142;PF07716.12|bZIP_2|Basic region leucine zipper|ENSGALT00000108231|m.11204:86-138;PF03131.14|bZIP_Maf|bZIP Maf transcription factor|ENSGALT00000108231|m.11204:88-142
ENSGALG00000049475	6.200122726	2.844524428	1.121371371	1.09E-07	3.88E-07	up	yes	7.384735973	5.780339074	5.43529313	3.096821516	2.762763865	2.673987902	30	981648	982703	+	S1PR2	protein_coding	GO:0003376|sphingosine-1-phosphate receptor signaling pathway; GO:0010800|positive regulation of peptidyl-threonine phosphorylation; GO:0031532|actin cytoskeleton reorganization; GO:0046847|filopodium assembly; GO:0090394|negative regulation of excitatory postsynaptic potential; GO:1903142|positive regulation of establishment of endothelial barrier	GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0001664|G protein-coupled receptor binding; GO:0004930|G protein-coupled receptor activity; GO:0005178|integrin binding; GO:0038036|sphingosine-1-phosphate receptor activity	"ko:K04292|S1PR2,EDG5"	ko04071|Sphingolipid signaling pathway; ko04080|Neuroactive ligand-receptor interaction	1056	XP_025001580.1	XP_025001580.1 sphingosine 1-phosphate receptor 2 [Gallus gallus]	sp|P47752|S1PR2_RAT	sp|P47752|S1PR2_RAT Sphingosine 1-phosphate receptor 2 OS=Rattus norvegicus GN=S1pr2 PE=1 SV=1	28377.ENSACAP00000004049	sphingosine-1-phosphate receptor 2	_	KOG3656	_	PF00001.18|7tm_1|7 transmembrane receptor (rhodopsin family)|ENSGALT00000094528|m.13714:50-288;PF10320.6|7TM_GPCR_Srsx|Serpentine type 7TM GPCR chemoreceptor Srsx|ENSGALT00000094528|m.13714:48-302
ENSGALG00000049484	1.933875878	0.954267575	1.011430661	2.03E-06	6.25E-06	up	yes	2.372843748	1.825053994	1.603729894	1.220680905	0.832645276	0.809476544	31	2459947	2469750	+	ENSGALG00000049484	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0001654|eye development; GO:0007165|signal transduction; GO:0021915|neural tube development; GO:0045892|negative regulation of transcription, DNA-templated; GO:0045944|positive regulation of transcription by RNA polymerase II"	GO:0005634|nucleus	"GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003700|DNA-binding transcription factor activity; GO:0043565|sequence-specific DNA binding; GO:0044212|transcription regulatory region DNA binding; GO:0046872|metal ion binding"	--	--	4530	XP_025001727.1	XP_025001727.1 uncharacterized protein LOC112531056 isoform X1 [Gallus gallus]	sp|Q9QX96|SALL2_MOUSE	sp|Q9QX96|SALL2_MOUSE Sal-like protein 2 OS=Mus musculus GN=Sall2 PE=1 SV=2	_	_	_	_	_	PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000094485|m.14039:1359-1382
ENSGALG00000049497	3.392671376	8.566264329	-1.333681546	8.86E-08	3.17E-07	down	yes	3.410426479	3.000633188	3.766954462	7.215894795	9.947482655	8.535415537	3	49427241	49428416	-	ENSGALG00000049497	protein_coding	GO:0006997|nucleus organization; GO:0007030|Golgi organization; GO:0007283|spermatogenesis; GO:0042692|muscle cell differentiation; GO:0090286|cytoskeletal anchoring at nuclear membrane; GO:0090292|nuclear matrix anchoring at nuclear membrane	GO:0000932|P-body; GO:0005634|nucleus; GO:0005635|nuclear envelope; GO:0005640|nuclear outer membrane; GO:0005654|nucleoplasm; GO:0005730|nucleolus; GO:0005737|cytoplasm; GO:0005794|Golgi apparatus; GO:0005856|cytoskeleton; GO:0016021|integral component of membrane; GO:0030017|sarcomere; GO:0031965|nuclear membrane; GO:0034993|meiotic nuclear membrane microtubule tethering complex; GO:0045211|postsynaptic membrane	GO:0003723|RNA binding; GO:0003779|actin binding; GO:0005521|lamin binding; GO:0019899|enzyme binding; GO:0042802|identical protein binding; GO:0042803|protein homodimerization activity; GO:0051015|actin filament binding	ko:K19326|SYNE1	--	618	XP_004935689.2	XP_004935689.2 nesprin-1 isoform X1 [Gallus gallus]	sp|Q8NF91|SYNE1_HUMAN	sp|Q8NF91|SYNE1_HUMAN Nesprin-1 OS=Homo sapiens GN=SYNE1 PE=1 SV=4	9031.ENSGALP00000021957	chromosome 6 open reading frame 98	COG5069	KOG0516	_	PF00435.18|Spectrin|Spectrin repeat|ENSGALT00000091764|m.11955:10-106
ENSGALG00000049511	3.432172464	0.46288574	2.863755839	2.69E-18	2.28E-17	up	yes	4.541723505	2.835699394	2.919094492	0.266931417	0.659555056	0.462170749	12	2800947	2802431	-	AMIGO3	protein_coding	GO:0007157|heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; GO:0051965|positive regulation of synapse assembly	GO:0016021|integral component of membrane	--	--	--	1485	XP_025010378.1	XP_025010378.1 amphoterin-induced protein 3 [Gallus gallus]	sp|Q86WK7|AMGO3_HUMAN	sp|Q86WK7|AMGO3_HUMAN Amphoterin-induced protein 3 OS=Homo sapiens GN=AMIGO3 PE=2 SV=1	9258.ENSOANP00000024052	adhesion molecule with Ig-like domain 3	_	KOG0619	_	PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000105582|m.7236:59-117;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000105582|m.7236:105-165;PF00560.30|LRR_1|Leucine Rich Repeat|ENSGALT00000105582|m.7236:106-126;PF00560.30|LRR_1|Leucine Rich Repeat|ENSGALT00000105582|m.7236:180-199;PF13516.3|LRR_6|Leucine Rich repeat|ENSGALT00000105582|m.7236:81-94;PF13516.3|LRR_6|Leucine Rich repeat|ENSGALT00000105582|m.7236:178-190
ENSGALG00000049622	7.67451916	19.3254116	-1.331218581	4.31E-20	4.07E-19	down	yes	7.422994077	7.226986919	8.373576484	19.23986787	22.78026873	15.9560982	2	98595195	98602179	-	ENSGALG00000049622	protein_coding	--	GO:0005654|nucleoplasm; GO:0005829|cytosol	--	ko:K21436|--	--	1299	XP_015137982.2	XP_015137982.2 LOW QUALITY PROTEIN: ankyrin repeat domain-containing protein 12 [Gallus gallus]	sp|Q6UB98|ANR12_HUMAN	sp|Q6UB98|ANR12_HUMAN Ankyrin repeat domain-containing protein 12 OS=Homo sapiens GN=ANKRD12 PE=1 SV=3	9031.ENSGALP00000013668	similar to GAC-1	COG0666	KOG0504	NOG68237	_
ENSGALG00000049663	3.135385457	1.343372301	1.216678059	3.98E-07	1.33E-06	up	yes	3.42876941	3.23225577	2.745131192	1.447650961	1.397577987	1.184887955	KZ626838.1	1593664	1595169	+	ENSGALG00000049663	protein_coding	--	--	--	--	--	1506	XP_025002144.1	XP_025002144.1 uncharacterized protein LOC112531364 [Gallus gallus]	_	_	_	_	_	_	_	PF00607.17|Gag_p24|gag gene protein p24 (core nucleocapsid protein)|ENSGALT00000092237|m.9941:231-412
ENSGALG00000049721	4.355318925	2.152438997	1.013427624	5.00E-06	1.46E-05	up	yes	5.149196124	3.671959589	4.244801061	2.560370774	1.757517254	2.139428964	26	5499800	5503029	+	ENSGALG00000049721	protein_coding	"GO:0006355|regulation of transcription, DNA-templated; GO:0007283|spermatogenesis; GO:0008584|male gonad development; GO:0030217|T cell differentiation; GO:0045892|negative regulation of transcription, DNA-templated"	GO:0005634|nucleus; GO:0005654|nucleoplasm	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003677|DNA binding; GO:0003682|chromatin binding; GO:0046872|metal ion binding"	--	--	1494	XP_024999605.1	XP_024999605.1 myc-associated zinc finger protein [Gallus gallus]	sp|Q9HBE1|PATZ1_HUMAN	"sp|Q9HBE1|PATZ1_HUMAN POZ-, AT hook-, and zinc finger-containing protein 1 OS=Homo sapiens GN=PATZ1 PE=1 SV=1"	9544.ENSMMUP00000032491	MYC-associated zinc finger protein (purine-binding transcription factor)	_	KOG1721	_	PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000100089|m.8360:21-38;PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000100089|m.8360:55-74
ENSGALG00000049723	27.51602948	1.575802364	4.117511635	4.45E-98	5.17E-96	up	yes	28.81810375	27.88088337	25.84910131	1.795956038	1.82089513	1.110555925	2	148964049	148964883	+	ENSGALG00000049723	protein_coding	--	GO:0005882|intermediate filament	GO:0005200|structural constituent of cytoskeleton	--	--	618	XP_025003985.1	XP_025003985.1 feather keratin 1-like isoform X2 [Gallus gallus]	sp|P02451|KRFT_LARNO	sp|P02451|KRFT_LARNO Feather keratin OS=Larus novaehollandiae PE=1 SV=1	9031.ENSGALP00000023460	annotation not avaliable	_	_	NOG231326	_
ENSGALG00000049751	41.65834302	10.90813061	1.93222587	1.01E-67	6.17E-66	up	yes	40.04045389	41.43329017	43.501285	12.12074197	9.69975507	10.9038948	1	48102060	48102942	+	ENSGALG00000049751	protein_coding	GO:0006334|nucleosome assembly; GO:0042742|defense response to bacterium	GO:0000786|nucleosome; GO:0005634|nucleus	GO:0003677|DNA binding; GO:0046982|protein heterodimerization activity	--	--	883	XP_019336407.1	XP_019336407.1 PREDICTED: histone H2B 8-like [Alligator mississippiensis]	sp|P0C1H3|H2B1_CHICK	sp|P0C1H3|H2B1_CHICK Histone H2B 1/2/3/4/6 OS=Gallus gallus GN=H2B-I PE=1 SV=2	_	_	_	_	_	PF00125.21|Histone|Core histone H2A/H2B/H3/H4|ENSGALT00000105242|m.1182:19-113;PF00808.20|CBFD_NFYB_HMF|Histone-like transcription factor (CBF/NF-Y) and archaeal histone|ENSGALT00000105242|m.1182:54-111
ENSGALG00000049798	0.335707403	0.700602068	-1.03949039	0.005163611	0.009656697	down	yes	0.413616058	0.237336772	0.356169379	0.886134867	0.640109892	0.575561446	10	11683975	11720024	-	HDGFL3	protein_coding	GO:0007026|negative regulation of microtubule depolymerization; GO:0008283|cell population proliferation; GO:0031175|neuron projection development; GO:0046785|microtubule polymerization	GO:0005576|extracellular region; GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005829|cytosol	GO:0008017|microtubule binding; GO:0008083|growth factor activity; GO:0015631|tubulin binding	--	--	2930	XP_004370737.1	XP_004370737.1 hepatoma-derived growth factor-related protein 3 [Trichechus manatus latirostris]	sp|Q9Y3E1|HDGR3_HUMAN	sp|Q9Y3E1|HDGR3_HUMAN Hepatoma-derived growth factor-related protein 3 OS=Homo sapiens GN=HDGFL3 PE=1 SV=1	13616.ENSMODP00000024179	similar to CGI-142 protein	_	KOG1904	_	PF00855.14|PWWP|PWWP domain|ENSGALT00000106566|m.5588:2-80
ENSGALG00000049799	0.57686407	1.40628829	-1.271016671	0.000697547	0.001504545	down	yes	0.699549784	0.403001115	0.628041311	1.014946909	1.037510185	2.166407774	18	1061028	1079459	+	ENSGALG00000049799	protein_coding	GO:0003341|cilium movement; GO:0030030|cell projection organization	GO:0005737|cytoplasm; GO:0005874|microtubule; GO:0005930|axoneme; GO:0030286|dynein complex; GO:0031514|motile cilium	"GO:0005524|ATP binding; GO:0008569|ATP-dependent microtubule motor activity, minus-end-directed; GO:0045503|dynein light chain binding; GO:0045505|dynein intermediate chain binding; GO:0051959|dynein light intermediate chain binding"	ko:K10408|DNAH	ko05016|Huntington's disease	2109	XP_415585.5	"XP_415585.5 dynein heavy chain 9, axonemal [Gallus gallus]"	sp|Q9NYC9|DYH9_HUMAN	"sp|Q9NYC9|DYH9_HUMAN Dynein heavy chain 9, axonemal OS=Homo sapiens GN=DNAH9 PE=1 SV=3"	9031.ENSGALP00000038608	"dynein, axonemal, heavy chain 9"	COG5245	KOG3595	_	"PF08385.9|DHC_N1|Dynein heavy chain, N-terminal region 1|ENSGALT00000101184|m.12527:1-512"
ENSGALG00000049810	3.836778886	1.60613631	1.251102021	6.73E-07	2.19E-06	up	yes	4.135496375	3.816941178	3.557899104	1.445755271	1.616331657	1.756322002	8	8900690	8901772	+	ENSGALG00000049810	protein_coding	GO:0006310|DNA recombination; GO:0015074|DNA integration	--	GO:0003677|DNA binding; GO:0003964|RNA-directed DNA polymerase activity; GO:0004523|RNA-DNA hybrid ribonuclease activity; GO:0008270|zinc ion binding	--	--	1083	RMB99531.1	RMB99531.1 hypothetical protein DUI87_24268 [Hirundo rustica rustica]	sp|P63133|POK8_HUMAN	sp|P63133|POK8_HUMAN Endogenous retrovirus group K member 8 Pol protein OS=Homo sapiens GN=ERVK-8 PE=3 SV=1	_	_	_	_	_	PF00078.24|RVT_1|Reverse transcriptase (RNA-dependent DNA polymerase)|ENSGALT00000102473|m.7321:19-149;PF06817.11|RVT_thumb|Reverse transcriptase thumb domain|ENSGALT00000102473|m.7321:156-219
ENSGALG00000049851	2.184301559	0.669755791	1.690673363	4.32E-09	1.76E-08	up	yes	2.191433675	2.1029667	2.258504301	0.654594199	0.802975773	0.551697402	8	21864386	21868833	+	ENSGALG00000049851	protein_coding	GO:0001819|positive regulation of cytokine production; GO:0016477|cell migration; GO:0031032|actomyosin structure organization; GO:0043123|positive regulation of I-kappaB kinase/NF-kappaB signaling	GO:0005737|cytoplasm; GO:0042641|actomyosin	--	--	--	1635	POI31440.1	POI31440.1 hypothetical protein CIB84_004810 [Bambusicola thoracicus]	sp|Q96LR2|LURA1_HUMAN	sp|Q96LR2|LURA1_HUMAN Leucine rich adaptor protein 1 OS=Homo sapiens GN=LURAP1 PE=1 SV=1	_	_	_	_	_	PF14854.3|LURAP|Leucine rich adaptor protein|ENSGALT00000097395|m.7895:32-72
ENSGALG00000049852	8.455243719	0.78386363	3.414588497	1.03E-30	1.67E-29	up	yes	7.42969976	8.828645824	9.107385572	0.706697681	0.945698101	0.699195108	2	148949834	148960922	+	ENSGALG00000049852	protein_coding	--	GO:0005882|intermediate filament	GO:0005200|structural constituent of cytoskeleton	--	--	617	XP_019469955.1	XP_019469955.1 PREDICTED: uncharacterized protein LOC100543202 [Meleagris gallopavo]	sp|P02450|KRFC_CHICK	sp|P02450|KRFC_CHICK Feather keratin 1 OS=Gallus gallus PE=3 SV=2	9031.ENSGALP00000018710	similar to feather beta keratin	_	_	NOG231326	_
ENSGALG00000049859	138.2395156	48.44319506	1.512610719	7.42E-50	2.65E-48	up	yes	125.7830871	152.0561251	136.8793347	51.07373331	43.12097553	51.13487635	1	48101375	48101764	-	H2A-IX	protein_coding	GO:0006342|chromatin silencing	GO:0000786|nucleosome; GO:0000790|nuclear chromatin; GO:0005654|nucleoplasm	GO:0003677|DNA binding; GO:0046982|protein heterodimerization activity	ko:K11251|H2A	ko05034|Alcoholism; ko05322|Systemic lupus erythematosus	390	EOB06724.1	"EOB06724.1 Histone H2A.J, partial [Anas platyrhynchos]"	sp|P70082|H2AJ_CHICK	sp|P70082|H2AJ_CHICK Histone H2A.J OS=Gallus gallus GN=H2A-IX PE=3 SV=1	9031.ENSGALP00000019172	Histone H2A.J (H2a/j)(Histone H2A-IX); Core component of nucleosome. Nucleosomes wrap and co [...] 	COG5262	KOG1756	_	PF16211.2|Histone_H2A_C|C-terminus of histone H2A|ENSGALT00000045162|m.1181:92-125;PF00125.21|Histone|Core histone H2A/H2B/H3/H4|ENSGALT00000045162|m.1181:7-89;PF00808.20|CBFD_NFYB_HMF|Histone-like transcription factor (CBF/NF-Y) and archaeal histone|ENSGALT00000045162|m.1181:25-88
ENSGALG00000049871	1.11987911	0.551405256	1.009053947	0.00216752	0.004323233	up	yes	0.881964667	1.441121893	1.03655077	0.502363395	0.607932627	0.543919745	2	7000145	7002235	-	ENSGALG00000049871	protein_coding	GO:0006310|DNA recombination; GO:0015074|DNA integration; GO:0044826|viral genome integration into host DNA; GO:0046718|viral entry into host cell; GO:0075713|establishment of integrated proviral latency	GO:0019028|viral capsid	GO:0003677|DNA binding; GO:0003887|DNA-directed DNA polymerase activity; GO:0003964|RNA-directed DNA polymerase activity; GO:0004190|aspartic-type endopeptidase activity; GO:0004523|RNA-DNA hybrid ribonuclease activity; GO:0005198|structural molecule activity; GO:0008270|zinc ion binding	--	--	2091	XP_015707163.1	XP_015707163.1 PREDICTED: LOW QUALITY PROTEIN: endogenous retrovirus group K member 18 Pol protein-like [Coturnix japonica]	sp|O92956|POL_RSVSB	sp|O92956|POL_RSVSB Gag-Pro-Pol polyprotein OS=Rous sarcoma virus (strain Schmidt-Ruppin B) GN=gag-pro-pol PE=1 SV=2	59729.ENSTGUP00000016902	similar to polymerase	_	KOG0017	_	PF00665.23|rve|Integrase core domain|ENSGALT00000090693|m.14739:480-590;PF00078.24|RVT_1|Reverse transcriptase (RNA-dependent DNA polymerase)|ENSGALT00000090693|m.14739:2-81;PF02022.16|Integrase_Zn|Integrase Zinc binding domain|ENSGALT00000090693|m.14739:429-465;PF06817.11|RVT_thumb|Reverse transcriptase thumb domain|ENSGALT00000090693|m.14739:95-146;PF00075.21|RNase_H|RNase H|ENSGALT00000090693|m.14739:297-420;PF00552.18|IN_DBD_C|Integrase DNA binding domain|ENSGALT00000090693|m.14739:654-691
ENSGALG00000049970	7.991344048	3.849828231	1.051705715	7.18E-14	4.39E-13	up	yes	7.523774427	7.99431335	8.455944369	4.472413396	3.560994195	3.516077101	W	5291751	5293886	+	ENSGALG00000049970	protein_coding	--	--	--	--	--	2136	XP_014793918.1	XP_014793918.1 PREDICTED: uncharacterized protein LOC106885910 [Calidris pugnax]	_	_	_	_	_	_	_	PF00075.21|RNase_H|RNase H|ENSGALT00000088117|m.10174:383-526;PF00078.24|RVT_1|Reverse transcriptase (RNA-dependent DNA polymerase)|ENSGALT00000088117|m.10174:9-132;PF00665.23|rve|Integrase core domain|ENSGALT00000088117|m.10174:609-711
ENSGALG00000050002	0.513405444	1.302127909	-1.325907528	7.51E-06	2.15E-05	down	yes	0.341706155	0.638875087	0.55963509	1.163215968	1.554150657	1.189017102	3	93724843	93761026	+	COLEC11	protein_coding	GO:0007275|multicellular organism development; GO:0032502|developmental process	GO:0005576|extracellular region; GO:0005581|collagen trimer	GO:0005537|mannose binding	ko:K10066|COLEC11	ko04145|Phagosome	3084	EOB06484.1	"EOB06484.1 Collectin-11, partial [Anas platyrhynchos]"	sp|Q2LK94|COL11_CHICK	sp|Q2LK94|COL11_CHICK Collectin-11 OS=Gallus gallus GN=COLEC11 PE=2 SV=1	_	_	_	_	_	PF00059.18|Lectin_C|Lectin C-type domain|ENSGALT00000106845|m.12917:160-266;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000106845|m.12917:40-87;PF01391.15|Collagen|Collagen triple helix repeat (20 copies)|ENSGALT00000106845|m.12917:58-112
ENSGALG00000050049	7.437651686	3.607547082	1.041773809	1.23E-15	8.61E-15	up	yes	7.299658369	7.811196115	7.202100575	3.173885277	4.333483335	3.315272635	9	3700823	3720928	-	C3orf70	protein_coding	--	--	--	--	--	3472	XP_015132652.1	XP_015132652.1 UPF0524 protein C3orf70 homolog [Gallus gallus]	sp|A6NLC5|CC070_HUMAN	sp|A6NLC5|CC070_HUMAN UPF0524 protein C3orf70 OS=Homo sapiens GN=C3orf70 PE=2 SV=1	9544.ENSMMUP00000000578	UPF0524 protein C3orf70 	_	_	NOG40600	PF15823.2|UPF0524|UPF0524 of C3orf70|ENSGALT00000102865|m.8371:58-293
ENSGALG00000050054	0.34726617	2.492955651	-2.808561512	9.17E-15	5.99E-14	down	yes	0.356678142	0.166419733	0.518700637	2.597899748	2.551992306	2.328974899	14	13691804	13713916	+	ENSGALG00000050054	protein_coding	GO:0006605|protein targeting; GO:0006974|cellular response to DNA damage stimulus; GO:0008286|insulin receptor signaling pathway; GO:0010838|positive regulation of keratinocyte proliferation; GO:0050821|protein stabilization; GO:0061178|regulation of insulin secretion involved in cellular response to glucose stimulus; GO:1902808|positive regulation of cell cycle G1/S phase transition; GO:1904659|glucose transmembrane transport	GO:0005737|cytoplasm; GO:0070062|extracellular exosome	GO:0019905|syntaxin binding	--	--	1625	XP_003642201.3	XP_003642201.3 syntaxin-binding protein 4 isoform X1 [Gallus gallus]	sp|Q6ZWJ1|STXB4_HUMAN	sp|Q6ZWJ1|STXB4_HUMAN Syntaxin-binding protein 4 OS=Homo sapiens GN=STXBP4 PE=1 SV=2	_	_	_	_	_	PF00595.21|PDZ|PDZ domain (Also known as DHR or GLGF)|ENSGALT00000003325|m.9993:20-96;PF00595.21|PDZ|PDZ domain (Also known as DHR or GLGF)|ENSGALT00000003325|m.9993:185-252
ENSGALG00000050173	5.446289928	24.18584207	-2.148766938	6.54E-99	7.82E-97	down	yes	5.277227722	5.516187128	5.545454932	25.02142714	23.35438549	24.18171357	23	2329424	2335100	-	TCEA3	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated"	GO:0005634|nucleus	GO:0003677|DNA binding; GO:0008270|zinc ion binding	--	--	1947	XP_024998815.1	XP_024998815.1 transcription elongation factor A protein 3 isoform X1 [Gallus gallus]	sp|O75764|TCEA3_HUMAN	sp|O75764|TCEA3_HUMAN Transcription elongation factor A protein 3 OS=Homo sapiens GN=TCEA3 PE=1 SV=2	59729.ENSTGUP00000000953	Transcription elongation factor A protein 3 (Transcription elongation factor S-II protein 3) [...] 	COG1594	KOG1105	_	"PF07500.11|TFIIS_M|Transcription factor S-II (TFIIS), central domain|ENSGALT00000108311|m.5337:266-376;PF01096.15|TFIIS_C|Transcription factor S-II (TFIIS)|ENSGALT00000108311|m.5337:389-427;PF08711.8|Med26|TFIIS helical bundle-like domain|ENSGALT00000108311|m.5337:29-78"
ENSGALG00000050224	8.899673539	4.204312	1.080075445	3.40E-05	8.94E-05	up	yes	9.224099531	8.523381322	8.951539765	3.659744948	4.297758876	4.655432175	26	1732672	1735583	-	GOLT1A	protein_coding	GO:0015031|protein transport; GO:0016192|vesicle-mediated transport	GO:0000137|Golgi cis cisterna; GO:0000139|Golgi membrane; GO:0005635|nuclear envelope; GO:0005783|endoplasmic reticulum; GO:0005802|trans-Golgi network; GO:0016021|integral component of membrane	--	--	--	417	XP_015154608.1	XP_015154608.1 vesicle transport protein GOT1A [Gallus gallus]	sp|Q9DCQ3|GOT1A_MOUSE	sp|Q9DCQ3|GOT1A_MOUSE Vesicle transport protein GOT1A OS=Mus musculus GN=Golt1a PE=2 SV=1	_	_	_	_	_	PF04178.9|Got1|Got1/Sft2-like family|ENSGALT00000095206|m.7886:18-112
ENSGALG00000050258	5.460714525	1.545406147	1.814437929	1.25E-11	6.41E-11	up	yes	6.3020817	5.315532645	4.76452923	1.17634659	1.255595253	2.204276598	15	7189366	7190553	-	ENSGALG00000050258	protein_coding	--	--	--	--	--	1112	_	_	_	_	_	_	_	_	_	_
ENSGALG00000050267	129.4472047	64.49361537	1.005023328	2.32E-57	1.05E-55	up	yes	136.5856666	126.9669981	124.7889493	64.80847986	62.36146795	66.31089829	1	813323	831335	+	CALU	protein_coding	--	GO:0005576|extracellular region; GO:0005789|endoplasmic reticulum membrane; GO:0005794|Golgi apparatus; GO:0033018|sarcoplasmic reticulum lumen; GO:0042470|melanosome	GO:0005509|calcium ion binding	--	--	1871	XP_025008752.1	XP_025008752.1 calumenin [Gallus gallus]	sp|Q28BT4|CALU_XENTR	sp|Q28BT4|CALU_XENTR Calumenin OS=Xenopus tropicalis GN=calu PE=2 SV=1	8364.ENSXETP00000049856	Hypothetical protein MGC69231; Involved in regulation of vitamin K-dependent carboxylation o [...] 	_	KOG4223	_	PF13202.3|EF-hand_5|EF hand|ENSGALT00000103461|m.96:43-62;PF13202.3|EF-hand_5|EF hand|ENSGALT00000103461|m.96:127-138;PF13833.3|EF-hand_8|EF-hand domain pair|ENSGALT00000103461|m.96:116-140
ENSGALG00000050309	65.89416755	24.06085223	1.453082478	3.79E-51	1.41E-49	up	yes	62.18155904	65.52049028	69.98045334	25.90263622	22.4606219	23.81929858	1	48160179	48160872	+	ENSGALG00000050309	protein_coding	GO:0006334|nucleosome assembly; GO:0042742|defense response to bacterium	GO:0000786|nucleosome; GO:0005634|nucleus	GO:0003677|DNA binding; GO:0046982|protein heterodimerization activity	ko:K11252|H2B	ko05034|Alcoholism; ko05203|Viral carcinogenesis; ko05322|Systemic lupus erythematosus	694	PKK29838.1	PKK29838.1 histone H2B 1/2/3/4/6 [Columba livia]	sp|P0C1H3|H2B1_CHICK	sp|P0C1H3|H2B1_CHICK Histone H2B 1/2/3/4/6 OS=Gallus gallus GN=H2B-I PE=1 SV=2	_	_	_	_	_	PF00125.21|Histone|Core histone H2A/H2B/H3/H4|ENSGALT00000042841|m.1210:27-120;PF00808.20|CBFD_NFYB_HMF|Histone-like transcription factor (CBF/NF-Y) and archaeal histone|ENSGALT00000042841|m.1210:61-118
ENSGALG00000050350	77.95174808	22.01783482	1.823438744	1.30E-61	6.75E-60	up	yes	77.99940749	77.26630459	78.58953217	22.10854206	20.78443727	23.16052514	1	48071383	48071763	-	HIST1H2B7	protein_coding	GO:0006334|nucleosome assembly; GO:0042742|defense response to bacterium	GO:0000786|nucleosome; GO:0005634|nucleus	GO:0003677|DNA binding; GO:0046982|protein heterodimerization activity	--	--	381	XP_003768757.1	XP_003768757.1 histone H2B type 2-E-like [Sarcophilus harrisii]	sp|P0C1H3|H2B1_CHICK	sp|P0C1H3|H2B1_CHICK Histone H2B 1/2/3/4/6 OS=Gallus gallus GN=H2B-I PE=1 SV=2	_	_	_	_	_	PF00125.21|Histone|Core histone H2A/H2B/H3/H4|ENSGALT00000104386|m.1165:10-101;PF00808.20|CBFD_NFYB_HMF|Histone-like transcription factor (CBF/NF-Y) and archaeal histone|ENSGALT00000104386|m.1165:42-99
ENSGALG00000050380	8.103738821	3.110390907	1.378640089	2.24E-25	2.86E-24	up	yes	8.23660794	7.485066935	8.589541587	2.923639511	3.083200678	3.324332531	2	44408018	44413032	-	TMPPE	protein_coding	--	GO:0016021|integral component of membrane	GO:0016787|hydrolase activity; GO:0046872|metal ion binding	--	--	2271	XP_011599307.1	XP_011599307.1 PREDICTED: transmembrane protein with metallophosphoesterase domain isoform X1 [Aquila chrysaetos canadensis]	sp|A5PJK1|TMPPE_BOVIN	sp|A5PJK1|TMPPE_BOVIN Transmembrane protein with metallophosphoesterase domain OS=Bos taurus GN=TMPPE PE=2 SV=1	_	_	_	_	_	PF00149.25|Metallophos|Calcineurin-like phosphoesterase|ENSGALT00000101476|m.586:285-459;PF12850.4|Metallophos_2|Calcineurin-like phosphoesterase superfamily domain|ENSGALT00000101476|m.586:286-489
ENSGALG00000050394	0.926661333	2.953816944	-1.66185693	2.06E-05	5.58E-05	down	yes	0.813761994	1.243022918	0.723199086	3.060950997	3.352498899	2.448000937	4	57115081	57118698	+	ENSGALG00000050394	protein_coding	--	GO:0016021|integral component of membrane	GO:0008270|zinc ion binding	--	--	777	XP_015131826.1	XP_015131826.1 protein ZGRF1 [Gallus gallus]	sp|Q86YA3|ZGRF1_HUMAN	sp|Q86YA3|ZGRF1_HUMAN Protein ZGRF1 OS=Homo sapiens GN=ZGRF1 PE=1 SV=3	9031.ENSGALP00000019689	prematurely terminated mRNA decay factor-like	COG1112	KOG1802	_	PF13086.3|AAA_11|AAA domain|ENSGALT00000099966|m.865:139-223
ENSGALG00000050439	0.012882528	0.331085476	-3.897814969	2.32E-08	8.83E-08	down	yes	0.022298387	0.016349197	0	0.264206186	0.401261345	0.327788896	16	782931	894180	+	ENSGALG00000050439	protein_coding	GO:0006953|acute-phase response	GO:0005576|extracellular region; GO:0005886|plasma membrane; GO:0016021|integral component of membrane	GO:0001618|virus receptor activity; GO:0005044|scavenger receptor activity	--	--	3428	XP_025011557.1	XP_025011557.1 deleted in malignant brain tumors 1 protein-like [Gallus gallus]	sp|Q2VL90|C163A_PIG	sp|Q2VL90|C163A_PIG Scavenger receptor cysteine-rich type 1 protein M130 OS=Sus scrofa GN=CD163 PE=1 SV=1	9031.ENSGALP00000003107	similar to CD163v3	_	_	NOG83796	PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000098808|m.11230:8-102;PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000098808|m.11230:227-269
ENSGALG00000050454	0.569046111	0.152828599	1.83032412	0.000110195	0.000268745	up	yes	0.531588873	0.592437364	0.583112096	0.231949182	0.084096583	0.142440034	25	494021	496498	-	ENSGALG00000050454	protein_coding	--	--	--	--	--	2478	XP_015731928.1	XP_015731928.1 PREDICTED: uncharacterized protein LOC107320518 [Coturnix japonica]	_	_	_	_	_	_	_	PF00665.23|rve|Integrase core domain|ENSGALT00000090531|m.6635:507-618;PF00075.21|RNase_H|RNase H|ENSGALT00000090531|m.6635:303-434
ENSGALG00000050532	0.417227673	1.288425404	-1.603686127	9.92E-05	0.000243553	down	yes	0.427610281	0.679302498	0.144770241	1.081234708	1.183828123	1.600213379	28	3421308	3424534	+	B3GNT3	protein_coding	"GO:0009101|glycoprotein biosynthetic process; GO:0016266|O-glycan processing; GO:0016269|O-glycan processing, core 3"	GO:0000139|Golgi membrane; GO:0016020|membrane; GO:0016021|integral component of membrane	"GO:0008378|galactosyltransferase activity; GO:0008499|UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity; GO:0047223|beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity; GO:0047224|acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity"	--	--	2218	XP_025000064.1	"XP_025000064.1 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 [Gallus gallus]"	sp|Q6ZMB0|B3GN6_HUMAN	"sp|Q6ZMB0|B3GN6_HUMAN Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase OS=Homo sapiens GN=B3GNT6 PE=1 SV=2"	_	_	_	_	_	PF01762.18|Galactosyl_T|Galactosyltransferase|ENSGALT00000105277|m.10195:133-325;PF10291.6|muHD|Muniscin C-terminal mu homology domain|ENSGALT00000105277|m.10198:55-114
ENSGALG00000050539	1.12503649	0.512557946	1.119075749	4.53E-05	0.00011701	up	yes	1.162675135	1.198406067	1.014028267	0.405646976	0.586454659	0.545572204	33	6339683	6343077	-	ENSGALG00000050539	protein_coding	--	--	--	--	--	3127	XP_021239331.1	XP_021239331.1 coiled-coil domain-containing protein 87-like [Numida meleagris]	sp|Q8CDL9|CCD87_MOUSE	sp|Q8CDL9|CCD87_MOUSE Coiled-coil domain-containing protein 87 OS=Mus musculus GN=Ccdc87 PE=2 SV=2	_	_	_	_	_	PF15140.3|DUF4573|Domain of unknown function (DUF4573)|ENSGALT00000106519|m.15343:210-313;PF15140.3|DUF4573|Domain of unknown function (DUF4573)|ENSGALT00000106519|m.15343:238-349;PF15140.3|DUF4573|Domain of unknown function (DUF4573)|ENSGALT00000106519|m.15343:291-400
ENSGALG00000050568	0.614048027	1.472736691	-1.248533455	6.58E-05	0.000165685	down	yes	0.436222524	0.723845555	0.682076001	1.459486776	1.198590665	1.760132632	8	14951227	14968630	+	ENSGALG00000050568	protein_coding	GO:0000712|resolution of meiotic recombination intermediates; GO:0010501|RNA secondary structure unwinding	GO:0005730|nucleolus; GO:0005737|cytoplasm	GO:0003676|nucleic acid binding; GO:0003724|RNA helicase activity; GO:0005524|ATP binding	"ko:K15271|HFM1,MER3"	--	2295	XP_025008937.1	XP_025008937.1 probable ATP-dependent DNA helicase HFM1 [Gallus gallus]	sp|A2PYH4|HFM1_HUMAN	sp|A2PYH4|HFM1_HUMAN Probable ATP-dependent DNA helicase HFM1 OS=Homo sapiens GN=HFM1 PE=1 SV=2	59729.ENSTGUP00000006345	Probable ATP-dependent DNA helicase HFM1 (EC 3.6.1.-)(SEC63 domain-containing protein 1) [Ta [...] 	COG1204	KOG0952	_	PF02889.13|Sec63|Sec63 Brl domain|ENSGALT00000103233|m.7507:109-418
ENSGALG00000050576	0.232082424	1.562946825	-2.699899657	5.92E-07	1.94E-06	down	yes	0.176077157	0.419574753	0.100595362	2.053164206	1.079387014	1.556289255	1	49533356	49544172	-	ENSGALG00000050576	protein_coding	GO:0007127|meiosis I; GO:0007141|male meiosis I; GO:0007286|spermatid development; GO:0045141|meiotic telomere clustering	GO:0005623|cell	--	--	--	1197	XP_025010867.1	XP_025010867.1 meiosis inhibitor protein 1 [Gallus gallus]	sp|Q5TIA1|MEI1_HUMAN	sp|Q5TIA1|MEI1_HUMAN Meiosis inhibitor protein 1 OS=Homo sapiens GN=MEI1 PE=2 SV=2	9031.ENSGALP00000019421	meiosis inhibitor 1	_	_	NOG73841	_
ENSGALG00000050627	1.804081586	0.235033885	2.888186166	2.17E-14	1.38E-13	up	yes	2.350072049	1.813763019	1.24840969	0.290781363	0.195672612	0.218647681	KZ626838.1	1756805	1758508	+	ENSGALG00000050627	protein_coding	--	--	--	--	--	1704	XP_025002190.1	XP_025002190.1 endogenous retrovirus group K member 8 Gag polyprotein-like [Gallus gallus]	_	_	_	_	_	_	_	PF00607.17|Gag_p24|gag gene protein p24 (core nucleocapsid protein)|ENSGALT00000096776|m.9943:231-412;PF00098.20|zf-CCHC|Zinc knuckle|ENSGALT00000096776|m.9943:489-504
ENSGALG00000050634	53.46952794	14.16000799	1.916146159	6.74E-115	1.25E-112	up	yes	58.66636725	49.2710805	52.47113608	14.57967504	12.86246463	15.0378843	32	594320	602481	+	ENSGALG00000050634	protein_coding	GO:0007608|sensory perception of smell; GO:0050896|response to stimulus	GO:0005789|endoplasmic reticulum membrane; GO:0031090|organelle membrane	GO:0005506|iron ion binding; GO:0020037|heme binding; GO:0070330|aromatase activity	ko:K07417|CYP2G	--	3007	XP_025000270.1	XP_025000270.1 LOW QUALITY PROTEIN: cytochrome P450 2G1-like [Gallus gallus]	sp|P24461|CP2G1_RABIT	sp|P24461|CP2G1_RABIT Cytochrome P450 2G1 OS=Oryctolagus cuniculus GN=CYP2G1 PE=1 SV=1	_	_	_	_	_	PF00067.19|p450|Cytochrome P450|ENSGALT00000105423|m.14467:74-364;PF00067.19|p450|Cytochrome P450|ENSGALT00000105423|m.14467:667-740;PF00067.19|p450|Cytochrome P450|ENSGALT00000105423|m.14468:319-430
ENSGALG00000050692	2.291965931	6.450215008	-1.488715699	3.93E-19	3.50E-18	down	yes	2.077958444	2.122102732	2.675836618	7.118327767	6.193038163	6.039279093	18	9620206	9632778	+	CBX8	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006351|transcription, DNA-templated; GO:0008284|positive regulation of cell population proliferation; GO:0016574|histone ubiquitination; GO:0032967|positive regulation of collagen biosynthetic process; GO:0045739|positive regulation of DNA repair; GO:0070301|cellular response to hydrogen peroxide"	GO:0000790|nuclear chromatin; GO:0000792|heterochromatin; GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0031519|PcG protein complex; GO:0035102|PRC1 complex	GO:0003727|single-stranded RNA binding; GO:0035064|methylated histone binding; GO:0097027|ubiquitin-protein transferase activator activity	"ko:K11455|CBX8,PC3"	--	1815	XP_015151081.1	XP_015151081.1 chromobox protein homolog 8 isoform X2 [Gallus gallus]	sp|Q9HC52|CBX8_HUMAN	sp|Q9HC52|CBX8_HUMAN Chromobox protein homolog 8 OS=Homo sapiens GN=CBX8 PE=1 SV=3	59729.ENSTGUP00000003250	Chromobox protein homolog 8 (Polycomb 3 homolog)(Pc3)(hPc3)(Rectachrome 1) [Taeniopygia guttata]	_	KOG2748	_	PF00385.21|Chromo|Chromo (CHRromatin Organisation MOdifier) domain|ENSGALT00000107498|m.13079:13-60
ENSGALG00000050720	1.482336717	0.559512832	1.389772835	8.25E-07	2.66E-06	up	yes	1.34404421	1.419722415	1.683243528	0.479853364	0.630669832	0.5680153	1	75755935	75765705	+	ENSGALG00000050720	protein_coding	GO:0052548|regulation of endopeptidase activity	GO:0005615|extracellular space; GO:0070062|extracellular exosome	GO:0004867|serine-type endopeptidase inhibitor activity; GO:0030414|peptidase inhibitor activity	--	--	2211	XP_025007673.1	XP_025007673.1 alpha-2-macroglobulin-like protein 1 [Gallus gallus]	sp|A8K2U0|A2ML1_HUMAN	sp|A8K2U0|A2ML1_HUMAN Alpha-2-macroglobulin-like protein 1 OS=Homo sapiens GN=A2ML1 PE=1 SV=3	59729.ENSTGUP00000013496	alpha-2-macroglobulin-like 1	_	KOG1366	_	_
ENSGALG00000050806	6.149256618	2.801769263	1.131278027	3.00E-16	2.19E-15	up	yes	5.941098307	6.591129023	5.915542523	2.887576819	2.71049536	2.80723561	6	5169302	5174545	+	ENSGALG00000050806	protein_coding	--	--	--	--	--	2368	XP_421513.1	XP_421513.1 uncharacterized protein LOC423629 [Gallus gallus]	_	_	9031.ENSGALP00000003918	hypothetical gene supported by CR353074; CR353078	_	_	NOG83665	_
ENSGALG00000050814	4.956044673	2.084257261	1.245658564	4.85E-14	3.01E-13	up	yes	4.350824329	5.248110871	5.26919882	1.704430229	2.22030338	2.328038174	2	15910728	15919796	+	ENSGALG00000050814	protein_coding	--	GO:0016021|integral component of membrane; GO:0097225|sperm midpiece	--	--	--	2628	XP_425978.4	XP_425978.4 patched domain-containing protein 3 [Gallus gallus]	sp|Q0EEE2|PTHD3_MOUSE	sp|Q0EEE2|PTHD3_MOUSE Patched domain-containing protein 3 OS=Mus musculus GN=Ptchd3 PE=1 SV=1	59729.ENSTGUP00000001144	Patched domain-containing protein 3 (Patched-related protein) [Taeniopygia guttata]	_	KOG1934	_	PF02460.15|Patched|Patched family|ENSGALT00000075108|m.14922:64-849;PF12349.5|Sterol-sensing|Sterol-sensing domain of SREBP cleavage-activation|ENSGALT00000075108|m.14922:296-447
ENSGALG00000050815	0.257454782	0.770400109	-1.544918982	0.00027102	0.000622455	down	yes	0.151169844	0.147783815	0.473410686	0.638120953	0.810447639	0.862631736	4	61044872	61054955	-	ENSGALG00000050815	protein_coding	--	--	--	--	--	2439	XP_004936033.2	XP_004936033.2 coiled-coil domain-containing protein 110 [Gallus gallus]	_	_	_	_	_	_	_	_
ENSGALG00000050830	2.216020053	0.86630973	1.344953807	2.67E-15	1.82E-14	up	yes	2.123599895	2.468874351	2.055585912	0.869399369	0.895558383	0.833971437	25	1854812	1880902	+	SV2A	protein_coding	GO:0006836|neurotransmitter transport; GO:0006874|cellular calcium ion homeostasis	GO:0005783|endoplasmic reticulum; GO:0005911|cell-cell junction; GO:0016021|integral component of membrane; GO:0030672|synaptic vesicle membrane; GO:0031594|neuromuscular junction; GO:0043005|neuron projection; GO:0048786|presynaptic active zone	GO:0019901|protein kinase binding; GO:0022857|transmembrane transporter activity; GO:0038023|signaling receptor activity	--	--	2855	KFM07437.1	KFM07437.1 Synaptic vesicle glycoprotein 2A [Aptenodytes forsteri]	sp|Q29397|SV2A_BOVIN	sp|Q29397|SV2A_BOVIN Synaptic vesicle glycoprotein 2A OS=Bos taurus GN=SV2A PE=2 SV=1	_	_	_	_	_	_
ENSGALG00000050840	85.2637462	35.7199086	1.254969414	3.15E-106	4.53E-104	up	yes	82.4108807	84.8820012	88.4983567	36.37367901	36.41624271	34.36980409	2	98307894	98337161	+	APCDD1	protein_coding	GO:0016055|Wnt signaling pathway; GO:0030178|negative regulation of Wnt signaling pathway; GO:0043615|astrocyte cell migration	GO:0005887|integral component of plasma membrane	GO:0017147|Wnt-protein binding; GO:0042802|identical protein binding	--	--	4388	NP_001012959.1	NP_001012959.1 protein APCDD1 precursor [Gallus gallus]	sp|Q5R2I8|APCD1_CHICK	sp|Q5R2I8|APCD1_CHICK Protein APCDD1 OS=Gallus gallus GN=APCDD1 PE=2 SV=1	9031.ENSGALP00000001313	hypothetical protein LOC426765 	_	_	NOG42984	PF14921.3|APCDDC|Adenomatosis polyposis coli down-regulated 1|ENSGALT00000102628|m.1500:51-282;PF14921.3|APCDDC|Adenomatosis polyposis coli down-regulated 1|ENSGALT00000102628|m.1500:290-466
ENSGALG00000050857	0.109816296	0.358015359	-1.618941841	0.000277135	0.000635773	down	yes	0.073402957	0.125577927	0.130468003	0.326722939	0.396751548	0.350571589	6	18988964	19006416	-	PTPN20	protein_coding	--	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005815|microtubule organizing center; GO:0005874|microtubule	GO:0004725|protein tyrosine phosphatase activity	--	--	2578	XP_015143916.1	XP_015143916.1 FERM and PDZ domain-containing protein 2 isoform X1 [Gallus gallus]	sp|A1L1L3|PTN20_RAT	sp|A1L1L3|PTN20_RAT Tyrosine-protein phosphatase non-receptor type 20 OS=Rattus norvegicus GN=Ptpn20 PE=1 SV=1	9031.ENSGALP00000039205	hypothetical protein LOC771321	COG5599	KOG0792	_	"PF00102.24|Y_phosphatase|Protein-tyrosine phosphatase|ENSGALT00000091612|m.4826:2-189;PF00782.17|DSPc|Dual specificity phosphatase, catalytic domain|ENSGALT00000091612|m.4826:102-178"
ENSGALG00000051040	49.16021124	16.35240493	1.587399744	7.18E-26	9.36E-25	up	yes	47.63487348	54.43762369	45.40813655	15.36523968	19.62877946	14.06319563	5	45246386	45246781	+	TMEM251	protein_coding	--	GO:0016021|integral component of membrane	--	--	--	396	XP_008948291.1	XP_008948291.1 PREDICTED: transmembrane protein 251 [Merops nubicus]	sp|Q5ZLR7|TM251_CHICK	sp|Q5ZLR7|TM251_CHICK Transmembrane protein 251 OS=Gallus gallus GN=TMEM251 PE=2 SV=2	9031.ENSGALP00000028021	UPF0694 transmembrane protein C14orf109 homolog 	_	_	NOG47941	PF15190.3|DUF4583|Domain of unknown function (DUF4583)|ENSGALT00000107325|m.3768:2-129
ENSGALG00000051082	86.03906228	37.18075802	1.210215317	1.63E-14	1.05E-13	up	yes	83.63664937	84.01177563	90.46876185	38.22362557	37.21273778	36.10591072	3	64898746	64898951	-	ENSGALG00000051082	protein_coding	--	--	--	--	--	126	_	_	_	_	_	_	_	_	_	_
ENSGALG00000051088	3.51418657	1.732953186	1.015756481	0.000212759	0.000496383	up	yes	3.53545707	3.372983386	3.634119255	2.339264369	1.179255716	1.680339474	16	1967655	1973720	-	ENSGALG00000051088	protein_coding	GO:0002474|antigen processing and presentation of peptide antigen via MHC class I	GO:0016021|integral component of membrane; GO:0042612|MHC class I protein complex	--	--	--	1047	XP_015150536.1	"XP_015150536.1 class I histocompatibility antigen, F10 alpha chain-like isoform X3 [Gallus gallus]"	sp|P15979|HA1F_CHICK	"sp|P15979|HA1F_CHICK Class I histocompatibility antigen, F10 alpha chain OS=Gallus gallus PE=2 SV=1"	9031.ENSGALP00000009984	similar to class I alpha chain	_	_	NOG42056	"PF00129.15|MHC_I|Class I Histocompatibility antigen, domains alpha 1 and 2|ENSGALT00000098059|m.11361:22-196;PF07654.12|C1-set|Immunoglobulin C1-set domain|ENSGALT00000098059|m.11361:213-282"
ENSGALG00000051171	1.707892288	0.354399811	2.237045465	4.17E-09	1.71E-08	up	yes	2.107643564	1.571081527	1.444951774	0.396393154	0.444568174	0.222238106	18	8993695	8996331	+	ENSGALG00000051171	protein_coding	GO:0006754|ATP biosynthetic process; GO:0042407|cristae formation; GO:0042776|mitochondrial ATP synthesis coupled proton transport; GO:1902600|proton transmembrane transport	"GO:0000276|mitochondrial proton-transporting ATP synthase complex, coupling factor F(o); GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005739|mitochondrion; GO:0005743|mitochondrial inner membrane; GO:0005753|mitochondrial proton-transporting ATP synthase complex; GO:0016021|integral component of membrane; GO:0070062|extracellular exosome"	GO:0022857|transmembrane transporter activity	--	--	1500	XP_415700.4	XP_415700.4 uncharacterized protein C17orf80 homolog [Gallus gallus]	sp|P56134|ATPK_HUMAN	"sp|P56134|ATPK_HUMAN ATP synthase subunit f, mitochondrial OS=Homo sapiens GN=ATP5J2 PE=1 SV=3"	_	_	_	_	_	"PF10206.6|WRW|Mitochondrial F1F0-ATP synthase, subunit f|ENSGALT00000103470|m.12912:133-206"
ENSGALG00000051209	5.639642533	1.663654109	1.755158188	1.44E-17	1.16E-16	up	yes	5.592571133	5.408198026	5.918158441	1.955812464	1.865120351	1.170029512	1	75781700	75789641	+	ENSGALG00000051209	protein_coding	GO:0052548|regulation of endopeptidase activity	GO:0005615|extracellular space; GO:0070062|extracellular exosome	GO:0004867|serine-type endopeptidase inhibitor activity; GO:0030414|peptidase inhibitor activity	--	--	1743	XP_025007673.1	XP_025007673.1 alpha-2-macroglobulin-like protein 1 [Gallus gallus]	sp|A8K2U0|A2ML1_HUMAN	sp|A8K2U0|A2ML1_HUMAN Alpha-2-macroglobulin-like protein 1 OS=Homo sapiens GN=A2ML1 PE=1 SV=3	9031.ENSGALP00000023009	similar to Mug1 protein	_	KOG1366	_	PF07678.11|A2M_comp|A-macroglobulin complement component|ENSGALT00000106726|m.2276:2-162;PF07677.11|A2M_recep|A-macroglobulin receptor|ENSGALT00000106726|m.2276:271-358
ENSGALG00000051213	0.203702424	0.485133819	-1.212215221	0.027016126	0.043641157	down	yes	0.074422442	0.291021863	0.245662966	0.550546047	0.470940862	0.433914547	15	11060216	11062339	+	DUSP21	protein_coding	GO:0016311|dephosphorylation; GO:0035335|peptidyl-tyrosine dephosphorylation; GO:0035970|peptidyl-threonine dephosphorylation	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0005743|mitochondrial inner membrane	GO:0004725|protein tyrosine phosphatase activity; GO:0008138|protein tyrosine/serine/threonine phosphatase activity; GO:0016791|phosphatase activity; GO:0017017|MAP kinase tyrosine/serine/threonine phosphatase activity	ko:K14165|K14165	--	2124	XP_415295.4	XP_415295.4 dual specificity protein phosphatase 18 isoform X4 [Gallus gallus]	sp|Q5BIP9|DUS18_BOVIN	sp|Q5BIP9|DUS18_BOVIN Dual specificity protein phosphatase 18 OS=Bos taurus GN=DUSP18 PE=2 SV=1	_	_	_	_	_	"PF00782.17|DSPc|Dual specificity phosphatase, catalytic domain|ENSGALT00000095212|m.11048:37-165"
ENSGALG00000051237	0.872928228	0.348164753	1.301672798	0.003637159	0.006978055	up	yes	0.75119679	1.022873686	0.844714207	0.336382514	0.268800767	0.439310979	W	4669320	4670792	+	ENSGALG00000051237	protein_coding	--	--	--	--	--	1473	XP_025002549.1	XP_025002549.1 uncharacterized protein LOC112531552 [Gallus gallus]	_	_	9031.ENSGALP00000037400	ENS-1 	_	_	NOG255036	_
ENSGALG00000051251	85.23554602	23.47323604	1.859993229	1.03E-59	5.05E-58	up	yes	88.37166913	85.47965193	81.85531701	25.54186859	20.89382904	23.98401048	1	48174968	48175348	-	ENSGALG00000051251	protein_coding	GO:0006334|nucleosome assembly; GO:0042742|defense response to bacterium	GO:0000786|nucleosome; GO:0005634|nucleus	GO:0003677|DNA binding; GO:0046982|protein heterodimerization activity	--	--	381	XP_003768757.1	XP_003768757.1 histone H2B type 2-E-like [Sarcophilus harrisii]	sp|P0C1H3|H2B1_CHICK	sp|P0C1H3|H2B1_CHICK Histone H2B 1/2/3/4/6 OS=Gallus gallus GN=H2B-I PE=1 SV=2	_	_	_	_	_	PF00125.21|Histone|Core histone H2A/H2B/H3/H4|ENSGALT00000090832|m.1215:10-101;PF00808.20|CBFD_NFYB_HMF|Histone-like transcription factor (CBF/NF-Y) and archaeal histone|ENSGALT00000090832|m.1215:42-99
ENSGALG00000051258	0.489375863	1.0615038	-1.101438972	0.001039646	0.002184704	down	yes	0.251869451	0.62788106	0.588377077	1.105302772	1.241847642	0.837360987	6	21454931	21458894	+	ENSGALG00000051258	protein_coding	GO:0001778|plasma membrane repair; GO:0006936|muscle contraction; GO:0007520|myoblast fusion; GO:0008015|blood circulation; GO:0030947|regulation of vascular endothelial growth factor receptor signaling pathway; GO:0034605|cellular response to heat	GO:0005635|nuclear envelope; GO:0005886|plasma membrane; GO:0005901|caveola; GO:0016021|integral component of membrane; GO:0030659|cytoplasmic vesicle membrane; GO:0031410|cytoplasmic vesicle; GO:0031965|nuclear membrane; GO:0043231|intracellular membrane-bounded organelle; GO:0070062|extracellular exosome	GO:0005543|phospholipid binding	--	--	3138	XP_010712855.1	XP_010712855.1 PREDICTED: myoferlin isoform X1 [Meleagris gallopavo]	sp|Q9NZM1|MYOF_HUMAN	sp|Q9NZM1|MYOF_HUMAN Myoferlin OS=Homo sapiens GN=MYOF PE=1 SV=1	9031.ENSGALP00000038965	"fer-1-like 3, myoferlin (C. elegans)"	_	KOG1326	_	PF16165.2|Ferlin_C|Ferlin C-terminus|ENSGALT00000098245|m.4922:5-100
ENSGALG00000051263	2.716155916	6.753512533	-1.310904608	2.46E-08	9.35E-08	down	yes	2.426983498	2.996996057	2.724488193	6.630576395	7.42630927	6.203651933	1	42863331	42867926	-	ENSGALG00000051263	protein_coding	"GO:0000086|G2/M transition of mitotic cell cycle; GO:0010389|regulation of G2/M transition of mitotic cell cycle; GO:0015031|protein transport; GO:0030902|hindbrain development; GO:0030916|otic vesicle formation; GO:0042462|eye photoreceptor cell development; GO:0043312|neutrophil degranulation; GO:0045893|positive regulation of transcription, DNA-templated; GO:0048793|pronephros development; GO:0060271|cilium assembly; GO:0070201|regulation of establishment of protein localization; GO:0090316|positive regulation of intracellular protein transport; GO:0097711|ciliary basal body-plasma membrane docking"	GO:0005576|extracellular region; GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005813|centrosome; GO:0005814|centriole; GO:0005829|cytosol; GO:0016020|membrane; GO:0032391|photoreceptor connecting cilium; GO:0032991|protein-containing complex; GO:0034451|centriolar satellite; GO:0035580|specific granule lumen; GO:0035869|ciliary transition zone; GO:0036038|MKS complex; GO:0036064|ciliary basal body	GO:0042802|identical protein binding	"ko:K16533|CEP290,NPHP6"	--	825	XP_004937659.1	XP_004937659.1 centrosomal protein of 290 kDa [Gallus gallus]	sp|O15078|CE290_HUMAN	sp|O15078|CE290_HUMAN Centrosomal protein of 290 kDa OS=Homo sapiens GN=CEP290 PE=1 SV=2	9031.ENSGALP00000018199	centrosomal protein 290kDa	_	_	NOG136455	_
ENSGALG00000051325	17.87969096	5.7830605	1.626730828	6.33E-35	1.26E-33	up	yes	17.64737286	16.60176435	19.38993566	7.072379047	4.755571596	5.521230857	1	48119142	48121729	-	ENSGALG00000051325	protein_coding	GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006334|nucleosome assembly	GO:0000786|nucleosome; GO:0005634|nucleus	GO:0031492|nucleosomal DNA binding; GO:0046982|protein heterodimerization activity	ko:K11253|H3	ko05034|Alcoholism; ko05202|Transcriptional misregulation in cancer; ko05322|Systemic lupus erythematosus	2099	XP_006268901.2	XP_006268901.2 PREDICTED: histone H3-like [Alligator mississippiensis]	sp|P84227|H32_BOVIN	sp|P84227|H32_BOVIN Histone H3.2 OS=Bos taurus PE=1 SV=2	9031.ENSGALP00000019185	Histone H3.2 (Histone H3 class I); Core component of nucleosome. Nucleosomes wrap and compac [...] 	COG2036	KOG1745	_	PF00125.21|Histone|Core histone H2A/H2B/H3/H4|ENSGALT00000052453|m.1189:15-146
ENSGALG00000051375	1.518988556	3.696199533	-1.277362946	0.005864881	0.010845632	down	yes	1.786138614	1.636997979	1.133829075	3.807165886	3.237718428	4.043714285	23	2355363	2360992	-	ENSGALG00000051375	protein_coding	GO:0006367|transcription initiation from RNA polymerase II promoter; GO:0007049|cell cycle; GO:0045944|positive regulation of transcription by RNA polymerase II; GO:0051726|regulation of cell cycle; GO:0072332|intrinsic apoptotic signaling pathway by p53 class mediator; GO:1990086|lens fiber cell apoptotic process	GO:0005654|nucleoplasm; GO:0090575|RNA polymerase II transcription factor complex	"GO:0001047|core promoter binding; GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific; GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity; GO:0008134|transcription factor binding; GO:0043565|sequence-specific DNA binding; GO:0046983|protein dimerization activity"	ko:K09389|E2F2	ko01522|Endocrine resistance; ko04110|Cell cycle; ko05161|Hepatitis B; ko05166|HTLV-I infection; ko05200|Pathways in cancer; ko05206|MicroRNAs in cancer; ko05212|Pancreatic cancer; ko05214|Glioma; ko05215|Prostate cancer; ko05218|Melanoma; ko05219|Bladder cancer; ko05220|Chronic myeloid leukemia; ko05222|Small cell lung cancer; ko05223|Non-small cell lung cancer; ko05224|Breast cancer	354	AAH99908.1	AAH99908.1 E2F3 protein [Homo sapiens]	sp|Q14209|E2F2_HUMAN	sp|Q14209|E2F2_HUMAN Transcription factor E2F2 OS=Homo sapiens GN=E2F2 PE=1 SV=1	_	_	_	_	_	PF02319.17|E2F_TDP|E2F/DP family winged-helix DNA-binding domain|ENSGALT00000098988|m.5341:54-103
ENSGALG00000051412	4.234201002	1.200801325	1.809530824	1.58E-21	1.62E-20	up	yes	5.14311297	3.452904243	4.106585794	1.212021404	1.168167793	1.222214776	23	6136961	6145221	-	PEA15L1	protein_coding	GO:0000077|DNA damage checkpoint; GO:0006915|apoptotic process; GO:0008643|carbohydrate transport; GO:0046325|negative regulation of glucose import; GO:1902042|negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; GO:1902043|positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	GO:0005634|nucleus; GO:0005829|cytosol	--	--	--	2551	XP_024998818.1	XP_024998818.1 astrocytic phosphoprotein PEA-15 [Gallus gallus]	sp|Q9Z297|PEA15_CRIGR	sp|Q9Z297|PEA15_CRIGR Astrocytic phosphoprotein PEA-15 OS=Cricetulus griseus GN=PEA15 PE=1 SV=1	_	_	_	_	_	PF01335.18|DED|Death effector domain|ENSGALT00000091112|m.5955:4-84
ENSGALG00000051443	2.622376976	1.164359996	1.164491379	2.78E-08	1.05E-07	up	yes	2.461757981	2.880998779	2.524374168	1.139674836	1.217020355	1.136384796	23	4394410	4396671	+	C1orf216	protein_coding	--	--	--	--	--	2226	XP_015153289.1	XP_015153289.1 UPF0500 protein C1orf216 homolog [Gallus gallus]	sp|Q8TAB5|CA216_HUMAN	sp|Q8TAB5|CA216_HUMAN UPF0500 protein C1orf216 OS=Homo sapiens GN=C1orf216 PE=1 SV=1	9031.ENSGALP00000003705	chromosome 1 open reading frame 216	_	_	NOG46130	PF15546.3|DUF4653|Domain of unknown function (DUF4653)|ENSGALT00000107801|m.5610:12-100;PF15546.3|DUF4653|Domain of unknown function (DUF4653)|ENSGALT00000107801|m.5610:100-217
ENSGALG00000051492	0.036191455	0.914539805	-4.323037542	1.70E-07	5.91E-07	down	yes	0	0.053250382	0.055323982	0.956151647	0.976609962	0.810857806	1	176859535	176878662	-	ENSGALG00000051492	protein_coding	--	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005874|microtubule; GO:0015630|microtubule cytoskeleton; GO:0045171|intercellular bridge	GO:0008017|microtubule binding; GO:0042803|protein homodimerization activity	--	--	1451	XP_417117.2	XP_417117.2 microtubule-associated tumor suppressor candidate 2 [Gallus gallus]	sp|Q3UHD3|MTUS2_MOUSE	sp|Q3UHD3|MTUS2_MOUSE Microtubule-associated tumor suppressor candidate 2 homolog OS=Mus musculus GN=Mtus2 PE=1 SV=1	9031.ENSGALP00000027552	KIAA0774	_	_	NOG119660	_
ENSGALG00000051505	1.97865663	5.901588096	-1.571751554	7.24E-26	9.43E-25	down	yes	1.948211911	2.136093563	1.851664417	6.279362379	5.259265626	6.166136282	6	15415982	15419961	+	ZNF503	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated; GO:0008285|negative regulation of cell population proliferation; GO:0010629|negative regulation of gene expression; GO:0061351|neural precursor cell proliferation; GO:0070315|G1 to G0 transition involved in cell differentiation"	GO:0005634|nucleus	GO:0003676|nucleic acid binding; GO:0046872|metal ion binding	--	--	2948	XP_015143780.2	XP_015143780.2 zinc finger protein 503 [Gallus gallus]	sp|Q96F45|ZN503_HUMAN	sp|Q96F45|ZN503_HUMAN Zinc finger protein 503 OS=Homo sapiens GN=ZNF503 PE=1 SV=1	59729.ENSTGUP00000006739	Zinc finger protein 503 [Taeniopygia guttata]	_	_	NOG72624	PF12402.5|nlz1|NocA-like zinc-finger protein 1|ENSGALT00000093238|m.4688:332-390
ENSGALG00000051529	3.816587091	0.344729528	3.431266902	0.022063116	0.036374055	up	yes	0.134932366	6.381148074	4.933680832	0.152263696	0.053365258	0.828559632	1	7249016	7265003	+	ENSGALG00000051529	protein_coding	GO:0000082|G1/S transition of mitotic cell cycle; GO:0006260|DNA replication; GO:0006270|DNA replication initiation; GO:0006974|cellular response to DNA damage stimulus; GO:0008283|cell population proliferation	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005730|nucleolus; GO:0031298|replication fork protection complex	GO:0003688|DNA replication origin binding; GO:0003697|single-stranded DNA binding; GO:0019899|enzyme binding; GO:0042802|identical protein binding; GO:0046872|metal ion binding	ko:K10736|MCM10	--	781	XP_025009949.1	XP_025009949.1 protein MCM10 homolog [Gallus gallus]	sp|Q7L590|MCM10_HUMAN	sp|Q7L590|MCM10_HUMAN Protein MCM10 homolog OS=Homo sapiens GN=MCM10 PE=1 SV=2	9031.ENSGALP00000005458	minichromosome maintenance complex component 10	_	KOG3056	_	_
ENSGALG00000051550	3.392384027	1.345305906	1.327927468	1.88E-10	8.72E-10	up	yes	3.323318571	3.143477486	3.710356023	1.23097537	1.615358901	1.189583448	5	55524724	55556323	+	ENSGALG00000051550	protein_coding	--	GO:0016021|integral component of membrane	--	--	--	2077	XP_009075154.1	XP_009075154.1 PREDICTED: uncharacterized protein C14orf37 homolog [Acanthisitta chloris]	sp|Q86TY3|CN037_HUMAN	sp|Q86TY3|CN037_HUMAN Uncharacterized protein C14orf37 OS=Homo sapiens GN=C14orf37 PE=1 SV=1	59729.ENSTGUP00000013434	Uncharacterized protein C14orf37 Precursor [Taeniopygia guttata]	_	_	NOG84792	_
ENSGALG00000051598	91.66985839	37.29876678	1.297090142	1.64E-68	1.02E-66	up	yes	92.20940593	90.3707424	92.42942684	36.31277661	37.05550086	38.52802287	Z	73243667	73249935	-	ENSGALG00000051598	protein_coding	GO:0007399|nervous system development	--	--	--	--	852	XP_021237206.1	"XP_021237206.1 vinculin-like, partial [Numida meleagris]"	sp|O75920|SERF1_HUMAN	sp|O75920|SERF1_HUMAN Small EDRK-rich factor 1 OS=Homo sapiens GN=SERF1A PE=2 SV=1	9031.ENSGALP00000033888	small EDRK-rich factor 1A (telomeric)	_	KOG4488	_	_
ENSGALG00000051608	80.75853447	8.786597215	3.198775903	6.61E-90	6.55E-88	up	yes	89.41518151	79.47762981	73.3827921	10.67725668	8.41985178	7.262683191	2	148907696	148907992	-	FK1L	protein_coding	--	GO:0005882|intermediate filament	GO:0005200|structural constituent of cytoskeleton	--	--	297	NP_001264689.2	NP_001264689.2 feather keratin 1-like [Gallus gallus]	sp|P02450|KRFC_CHICK	sp|P02450|KRFC_CHICK Feather keratin 1 OS=Gallus gallus PE=3 SV=2	9031.ENSGALP00000018710	similar to feather beta keratin	_	_	NOG231326	_
ENSGALG00000051749	0	0.397194275	-5.347645374	3.39E-08	1.27E-07	down	yes	0	0	0	0.358103614	0.499617855	0.333861357	KZ626828.1	30650	34138	+	ENSGALG00000051749	protein_coding	--	--	--	--	--	2878	_	_	_	_	_	_	_	_	_	_
ENSGALG00000051779	29.31101114	10.47609039	1.483457969	1.21E-52	4.80E-51	up	yes	28.02226974	30.55000269	29.36076098	12.06996656	10.02168337	9.336621244	3	88895	91751	+	PRORSD1P	protein_coding	--	--	GO:0002161|aminoacyl-tRNA editing activity	--	--	2514	NP_001182490.1	NP_001182490.1 PrdX-deacylase domain 1 [Gallus gallus]	sp|A1A4Q2|PRXD1_BOVIN	sp|A1A4Q2|PRXD1_BOVIN Prolyl-tRNA synthetase associated domain-containing protein 1 OS=Bos taurus GN=PRORSD1 PE=2 SV=1	9031.ENSGALP00000013150	similar to RIKEN cDNA 2010316F05	COG3760	_	_	PF04073.12|tRNA_edit|Aminoacyl-tRNA editing domain|ENSGALT00000096678|m.10517:46-175
ENSGALG00000051783	0.604066015	0.160969956	1.844650936	9.32E-05	0.000229964	up	yes	0.672542129	0.587937026	0.55171889	0.145947406	0.163684895	0.173277567	6	36299339	36301375	-	ENSGALG00000051783	protein_coding	--	--	--	--	--	2037	RMB96164.1	RMB96164.1 hypothetical protein DUI87_27225 [Hirundo rustica rustica]	_	_	_	_	_	_	_	PF00078.24|RVT_1|Reverse transcriptase (RNA-dependent DNA polymerase)|ENSGALT00000103444|m.5544:430-652;PF14529.3|Exo_endo_phos_2|Endonuclease-reverse transcriptase|ENSGALT00000103444|m.5544:44-118
ENSGALG00000051832	5.46237711	0.273759233	4.269428413	0	0	up	yes	5.797509358	5.25666088	5.332961092	0.31848282	0.263551007	0.239243871	KZ626838.1	91409	105989	-	ENSGALG00000051832	protein_coding	--	--	--	--	--	13442	XP_025002217.1	XP_025002217.1 zonadhesin-like [Gallus gallus]	_	_	_	_	_	_	_	_
ENSGALG00000051882	0.816512573	0.203258891	1.954430874	4.28E-14	2.67E-13	up	yes	0.713815751	0.848220877	0.887501089	0.160483058	0.26608672	0.183206895	9	15142821	15152169	-	ENSGALG00000051882	protein_coding	GO:0002223|stimulatory C-type lectin receptor signaling pathway; GO:0007160|cell-matrix adhesion; GO:0016266|O-glycan processing; GO:0030277|maintenance of gastrointestinal epithelium	GO:0005615|extracellular space; GO:0005796|Golgi lumen; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0016020|membrane; GO:0031012|extracellular matrix; GO:0031982|vesicle; GO:0070062|extracellular exosome	"GO:0005176|ErbB-2 class receptor binding; GO:0030197|extracellular matrix constituent, lubricant activity"	--	--	6422	OXB75648.1	OXB75648.1 hypothetical protein H355_001292 [Colinus virginianus]	sp|Q99102|MUC4_HUMAN	sp|Q99102|MUC4_HUMAN Mucin-4 OS=Homo sapiens GN=MUC4 PE=1 SV=4	_	_	_	_	_	PF06119.11|NIDO|Nidogen-like|ENSGALT00000098905|m.8990:1898-1981
ENSGALG00000051905	0.558604685	1.410641165	-1.321044305	2.30E-09	9.59E-09	down	yes	0.721496241	0.512971317	0.441346496	1.348723595	1.426745631	1.456454268	5	24465583	24473533	-	ENSGALG00000051905	protein_coding	GO:0042325|regulation of phosphorylation	GO:0005737|cytoplasm	GO:0004864|protein phosphatase inhibitor activity	"ko:K17557|PPP1R14D,GBPI"	--	4820	XP_015142630.1	XP_015142630.1 protein phosphatase 1 regulatory subunit 14D [Gallus gallus]	sp|Q9NXH3|PP14D_HUMAN	sp|Q9NXH3|PP14D_HUMAN Protein phosphatase 1 regulatory subunit 14D OS=Homo sapiens GN=PPP1R14D PE=1 SV=1	9031.ENSGALP00000040587	"protein phosphatase 1, regulatory (inhibitor) subunit 14D"	_	_	NOG81055	PF05361.9|PP1_inhibitor|PKC-activated protein phosphatase-1 inhibitor|ENSGALT00000099285|m.3047:102-184
ENSGALG00000051918	0.278506856	1.09798127	-1.941255983	1.42E-06	4.47E-06	down	yes	0.436264767	0.177705392	0.22155041	1.20340148	0.88187684	1.208665492	25	1512783	1516847	+	TTC24	protein_coding	--	--	--	--	--	2022	XP_024999300.1	XP_024999300.1 tetratricopeptide repeat protein 24 isoform X1 [Gallus gallus]	sp|A2A3L6|TTC24_HUMAN	sp|A2A3L6|TTC24_HUMAN Tetratricopeptide repeat protein 24 OS=Homo sapiens GN=TTC24 PE=4 SV=1	59729.ENSTGUP00000003720	Tetratricopeptide repeat protein 24 (TPR repeat protein 24) [Taeniopygia guttata]	_	KOG1124	_	PF13176.3|TPR_7|Tetratricopeptide repeat|ENSGALT00000094212|m.6702:464-495;PF13181.3|TPR_8|Tetratricopeptide repeat|ENSGALT00000094212|m.6702:465-491
ENSGALG00000051983	7.382656973	3.587919963	1.038929879	1.25E-08	4.88E-08	up	yes	7.513880799	8.194911093	6.439179027	3.638903286	3.751786896	3.373069707	33	4956605	4967991	+	LETMD1	protein_coding	GO:0006875|cellular metal ion homeostasis	GO:0005741|mitochondrial outer membrane; GO:0005743|mitochondrial inner membrane; GO:0016021|integral component of membrane	GO:0043022|ribosome binding	--	--	1122	XP_025001402.1	XP_025001402.1 LETM1 domain-containing protein 1 [Gallus gallus]	sp|Q28EM8|LTMD1_XENTR	sp|Q28EM8|LTMD1_XENTR LETM1 domain-containing protein 1 OS=Xenopus tropicalis GN=letmd1 PE=2 SV=1	_	_	_	_	_	PF07766.10|LETM1|LETM1-like protein|ENSGALT00000103032|m.15053:92-357
ENSGALG00000051993	6.050719174	15.55470801	-1.360717611	0.003255942	0.006292633	down	yes	7.615404227	6.900883692	3.635869603	8.97684242	18.01816144	19.66912017	2	98582916	98594266	-	ENSGALG00000051993	protein_coding	--	GO:0005654|nucleoplasm; GO:0005829|cytosol	--	ko:K21436|--	--	1894	EOB07452.1	"EOB07452.1 Ankyrin repeat domain-containing protein 12, partial [Anas platyrhynchos]"	sp|Q6UB98|ANR12_HUMAN	sp|Q6UB98|ANR12_HUMAN Ankyrin repeat domain-containing protein 12 OS=Homo sapiens GN=ANKRD12 PE=1 SV=3	9031.ENSGALP00000013667	annotation not avaliable	_	_	NOG68237	_
ENSGALG00000052012	13.00472892	27.39987404	-1.074550436	1.80E-22	1.95E-21	down	yes	13.33539909	12.87771743	12.80107024	28.22058257	27.5711165	26.40792305	2	98600320	98625150	-	ENSGALG00000052012	protein_coding	--	GO:0005654|nucleoplasm; GO:0005829|cytosol	--	ko:K21436|--	--	972	KFP66160.1	"KFP66160.1 Ankyrin repeat domain-containing protein 12, partial [Cariama cristata]"	sp|Q6UB98|ANR12_HUMAN	sp|Q6UB98|ANR12_HUMAN Ankyrin repeat domain-containing protein 12 OS=Homo sapiens GN=ANKRD12 PE=1 SV=3	9031.ENSGALP00000013668	similar to GAC-1	COG0666	KOG0504	NOG68237	PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000047118|m.1519:179-230;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000047118|m.1519:211-263;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000047118|m.1519:172-217;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000047118|m.1519:229-283;PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000047118|m.1519:172-239;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000047118|m.1519:177-207;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000047118|m.1519:210-239;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000047118|m.1519:242-271;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000047118|m.1519:177-205;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000047118|m.1519:210-237
ENSGALG00000052016	1.249967733	0.595964028	1.05608273	0.001974306	0.003968647	up	yes	1.346002899	1.203524994	1.200375305	0.592737427	0.584274761	0.610879895	22	5334110	5335714	+	ADRA2B	protein_coding	GO:0003056|regulation of vascular smooth muscle contraction; GO:0007186|G protein-coupled receptor signaling pathway; GO:0007267|cell-cell signaling; GO:0007565|female pregnancy; GO:0010700|negative regulation of norepinephrine secretion; GO:0030168|platelet activation; GO:0032148|activation of protein kinase B activity; GO:0032811|negative regulation of epinephrine secretion; GO:0045666|positive regulation of neuron differentiation; GO:0045777|positive regulation of blood pressure; GO:0070474|positive regulation of uterine smooth muscle contraction; GO:0071880|adenylate cyclase-activating adrenergic receptor signaling pathway; GO:0071883|activation of MAPK activity by adrenergic receptor signaling pathway	GO:0005622|intracellular; GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane	GO:0004938|alpha2-adrenergic receptor activity; GO:0051379|epinephrine binding	ko:K04139|ADRA2B	ko04022|cGMP-PKG signaling pathway; ko04080|Neuroactive ligand-receptor interaction	1605	XP_015128438.2	XP_015128438.2 LOW QUALITY PROTEIN: alpha-2B adrenergic receptor [Gallus gallus]	sp|P18089|ADA2B_HUMAN	sp|P18089|ADA2B_HUMAN Alpha-2B adrenergic receptor OS=Homo sapiens GN=ADRA2B PE=1 SV=4	_	_	_	_	_	PF00001.18|7tm_1|7 transmembrane receptor (rhodopsin family)|ENSGALT00000091645|m.5099:30-207;PF10320.6|7TM_GPCR_Srsx|Serpentine type 7TM GPCR chemoreceptor Srsx|ENSGALT00000091645|m.5099:25-205;PF10328.6|7TM_GPCR_Srx|Serpentine type 7TM GPCR chemoreceptor Srx|ENSGALT00000091645|m.5099:23-151;PF00001.18|7tm_1|7 transmembrane receptor (rhodopsin family)|ENSGALT00000091645|m.5101:16-84;PF10320.6|7TM_GPCR_Srsx|Serpentine type 7TM GPCR chemoreceptor Srsx|ENSGALT00000091645|m.5101:21-98
ENSGALG00000052030	107.0400356	30.92653546	1.79090173	1.11E-58	5.24E-57	up	yes	106.5981264	112.5314385	101.9905419	35.5737446	28.74731702	28.45854475	1	48159496	48159885	-	H2A-VII	protein_coding	GO:0006342|chromatin silencing	GO:0000786|nucleosome; GO:0000790|nuclear chromatin	GO:0003677|DNA binding; GO:0046982|protein heterodimerization activity	ko:K11251|H2A	ko05034|Alcoholism; ko05322|Systemic lupus erythematosus	390	EOB06730.1	"EOB06730.1 Histone H2A-IV, partial [Anas platyrhynchos]"	sp|P02263|H2A4_CHICK	sp|P02263|H2A4_CHICK Histone H2A-IV OS=Gallus gallus PE=1 SV=2	9031.ENSGALP00000019162	Histone H2A-IV 	COG5262	KOG1756	_	PF16211.2|Histone_H2A_C|C-terminus of histone H2A|ENSGALT00000095522|m.1208:92-125;PF00125.21|Histone|Core histone H2A/H2B/H3/H4|ENSGALT00000095522|m.1208:5-89;PF00808.20|CBFD_NFYB_HMF|Histone-like transcription factor (CBF/NF-Y) and archaeal histone|ENSGALT00000095522|m.1208:25-88
ENSGALG00000052087	4.163085491	1.329915173	1.638972806	7.12E-16	5.06E-15	up	yes	4.721921533	3.747232484	4.020102457	1.159716397	1.362178446	1.467850678	3	104461317	104465022	+	ENSGALG00000052087	protein_coding	GO:0007160|cell-matrix adhesion; GO:0010811|positive regulation of cell-substrate adhesion; GO:0016477|cell migration; GO:0030198|extracellular matrix organization; GO:0070207|protein homotrimerization	GO:0005576|extracellular region; GO:0005581|collagen trimer; GO:0005615|extracellular space; GO:0031012|extracellular matrix; GO:0034668|integrin alpha4-beta1 complex; GO:0070062|extracellular exosome; GO:1990971|EMILIN complex	GO:0030023|extracellular matrix constituent conferring elasticity; GO:0042802|identical protein binding; GO:0098640|integrin binding involved in cell-matrix adhesion	--	--	1897	XP_015140498.2	XP_015140498.2 LOW QUALITY PROTEIN: EMILIN-1 [Gallus gallus]	sp|Q99K41|EMIL1_MOUSE	sp|Q99K41|EMIL1_MOUSE EMILIN-1 OS=Mus musculus GN=Emilin1 PE=1 SV=1	_	_	_	_	_	PF07546.10|EMI|EMI domain|ENSGALT00000093048|m.13124:138-209
ENSGALG00000052192	426.9517742	108.6929921	1.97371526	4.72E-176	2.48E-173	up	yes	456.5637137	412.506957	411.784652	114.111601	98.74745474	113.2199205	33	7125098	7127729	+	TUBA1B	protein_coding	GO:0000226|microtubule cytoskeleton organization; GO:0018410|C-terminal protein amino acid modification; GO:0043687|post-translational protein modification; GO:0071353|cellular response to interleukin-4	GO:0005829|cytosol; GO:0005881|cytoplasmic microtubule; GO:0043209|myelin sheath; GO:0070062|extracellular exosome	GO:0003725|double-stranded RNA binding; GO:0003924|GTPase activity; GO:0005200|structural constituent of cytoskeleton; GO:0005525|GTP binding; GO:0031625|ubiquitin protein ligase binding	ko:K07374|TUBA	ko04145|Phagosome; ko04210|Apoptosis; ko04530|Tight junction; ko04540|Gap junction; ko05130|Pathogenic Escherichia coli infection	1901	XP_005061428.1	XP_005061428.1 PREDICTED: tubulin alpha-1A chain [Ficedula albicollis]	sp|P81947|TBA1B_BOVIN	sp|P81947|TBA1B_BOVIN Tubulin alpha-1B chain OS=Bos taurus PE=1 SV=2	_	_	_	_	_	"PF00091.22|Tubulin|Tubulin/FtsZ family, GTPase domain|ENSGALT00000055441|m.15638:18-228;PF03953.14|Tubulin_C|Tubulin C-terminal domain|ENSGALT00000055441|m.15638:278-406"
ENSGALG00000052240	2.891581655	7.062381396	-1.285356549	1.80E-17	1.43E-16	down	yes	3.374842484	3.033181379	2.266721102	7.343647276	6.307712825	7.535784088	16	2529852	2544064	+	ENSGALG00000052240	protein_coding	--	GO:0005615|extracellular space; GO:0016021|integral component of membrane	--	--	--	2846	XP_015150487.1	XP_015150487.1 E3 ubiquitin-protein ligase TRIM39 isoform X1 [Gallus gallus]	sp|Q62556|BT1A1_MOUSE	sp|Q62556|BT1A1_MOUSE Butyrophilin subfamily 1 member A1 OS=Mus musculus GN=Btn1a1 PE=1 SV=2	_	_	_	_	_	_
ENSGALG00000052243	4.785153819	13.92936306	-1.539515641	3.70E-34	7.16E-33	down	yes	5.238458356	4.617182665	4.499820436	14.34855177	14.77804207	12.66149533	6	17408125	17413359	+	CYP2C18	protein_coding	GO:0006805|xenobiotic metabolic process; GO:0008202|steroid metabolic process; GO:0016098|monoterpenoid metabolic process; GO:0017144|drug metabolic process; GO:0019373|epoxygenase P450 pathway; GO:0019627|urea metabolic process; GO:0032787|monocarboxylic acid metabolic process; GO:0042737|drug catabolic process; GO:0042738|exogenous drug catabolic process; GO:0043603|cellular amide metabolic process; GO:0055114|oxidation-reduction process; GO:0070989|oxidative demethylation; GO:0097267|omega-hydroxylase P450 pathway	GO:0005789|endoplasmic reticulum membrane; GO:0031090|organelle membrane; GO:0043231|intracellular membrane-bounded organelle	GO:0001567|cholesterol 25-hydroxylase activity; GO:0004497|monooxygenase activity; GO:0005506|iron ion binding; GO:0008144|drug binding; GO:0008392|arachidonic acid epoxygenase activity; GO:0008395|steroid hydroxylase activity; GO:0016491|oxidoreductase activity; GO:0018675|(S)-limonene 6-monooxygenase activity; GO:0018676|(S)-limonene 7-monooxygenase activity; GO:0019825|oxygen binding; GO:0020037|heme binding; GO:0034875|caffeine oxidase activity; GO:0052741|(R)-limonene 6-monooxygenase activity	ko:K07413|CYP2C	ko00140|Steroid hormone biosynthesis; ko00590|Arachidonic acid metabolism; ko00591|Linoleic acid metabolism; ko00830|Retinol metabolism; ko01100|Metabolic pathways; ko04726|Serotonergic synapse; ko04750|Inflammatory mediator regulation of TRP channels; ko05204|Chemical carcinogenesis	1891	NP_001001752.1	NP_001001752.1 cytochrome P450 family 2 subfamily C member 18 [Gallus gallus]	sp|P11712|CP2C9_HUMAN	sp|P11712|CP2C9_HUMAN Cytochrome P450 2C9 OS=Homo sapiens GN=CYP2C9 PE=1 SV=3	59729.ENSTGUP00000007475	Cytochrome P450 2C8 (EC 1.14.14.1)(CYPIIC8)(P450 form 1)(P450 MP-12/MP-20)(P450 IIC2)(S-meph [...] 	COG2124	KOG0156	_	PF00067.19|p450|Cytochrome P450|ENSGALT00000008787|m.4758:34-490
ENSGALG00000052284	112.172064	31.71337279	1.822223962	2.60E-71	1.79E-69	up	yes	107.5008758	119.4791021	109.536214	36.69408655	29.54639334	28.89963848	1	48175636	48176207	+	H2A-VII	protein_coding	GO:0006342|chromatin silencing	GO:0000786|nucleosome; GO:0000790|nuclear chromatin	GO:0003677|DNA binding; GO:0046982|protein heterodimerization activity	--	--	572	XP_025002825.1	XP_025002825.1 histone H2A-IV isoform X1 [Gallus gallus]	sp|P02263|H2A4_CHICK	sp|P02263|H2A4_CHICK Histone H2A-IV OS=Gallus gallus PE=1 SV=2	9031.ENSGALP00000029990	Histone H2A-IV ; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromat [...] 	COG5262	KOG1756	_	PF16211.2|Histone_H2A_C|C-terminus of histone H2A|ENSGALT00000049616|m.1216:105-138;PF00125.21|Histone|Core histone H2A/H2B/H3/H4|ENSGALT00000049616|m.1216:16-102;PF00808.20|CBFD_NFYB_HMF|Histone-like transcription factor (CBF/NF-Y) and archaeal histone|ENSGALT00000049616|m.1216:38-101
ENSGALG00000052371	1.021091973	0.253452374	1.968558941	1.22E-06	3.86E-06	up	yes	0.758521511	0.421905858	1.882848551	0.241043243	0.305164769	0.21414911	16	1926484	1964781	-	ENSGALG00000052371	protein_coding	GO:0002474|antigen processing and presentation of peptide antigen via MHC class I	GO:0016021|integral component of membrane; GO:0042612|MHC class I protein complex	--	--	--	2289	XP_015150529.1	"XP_015150529.1 class I histocompatibility antigen, F10 alpha chain isoform X2 [Gallus gallus]"	sp|P15979|HA1F_CHICK	"sp|P15979|HA1F_CHICK Class I histocompatibility antigen, F10 alpha chain OS=Gallus gallus PE=2 SV=1"	9031.ENSGALP00000023473	MHC class I antigen Fragment 	_	_	NOG42056	"PF00129.15|MHC_I|Class I Histocompatibility antigen, domains alpha 1 and 2|ENSGALT00000076221|m.11356:70-243;PF07654.12|C1-set|Immunoglobulin C1-set domain|ENSGALT00000076221|m.11356:264-331"
ENSGALG00000052375	1.489673964	4.915157363	-1.715520935	2.79E-31	4.75E-30	down	yes	1.518510768	1.511653335	1.438857788	5.707206963	4.452973158	4.58529197	4	57098783	57108321	+	ENSGALG00000052375	protein_coding	--	GO:0016021|integral component of membrane	GO:0008270|zinc ion binding	--	--	3239	XP_015131826.1	XP_015131826.1 protein ZGRF1 [Gallus gallus]	sp|Q86YA3|ZGRF1_HUMAN	sp|Q86YA3|ZGRF1_HUMAN Protein ZGRF1 OS=Homo sapiens GN=ZGRF1 PE=1 SV=3	9031.ENSGALP00000019680	annotation not avaliable	_	_	NOG75832	PF10382.6|DUF2439|Protein of unknown function (DUF2439)|ENSGALT00000107705|m.863:4-76
ENSGALG00000052399	1.156716359	0.387367536	1.55390795	2.98E-13	1.73E-12	up	yes	1.484889787	0.951257522	1.034001767	0.372359069	0.37668231	0.41306123	14	16016858	16037621	-	ENSGALG00000052399	protein_coding	GO:0006361|transcription initiation from RNA polymerase I promoter; GO:0006363|termination of RNA polymerase I transcription; GO:0008203|cholesterol metabolic process; GO:0016042|lipid catabolic process; GO:0019433|triglyceride catabolic process	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005739|mitochondrion; GO:0005811|lipid droplet; GO:0005829|cytosol; GO:0005901|caveola	GO:0016298|lipase activity; GO:0033878|hormone-sensitive lipase activity; GO:0042134|rRNA primary transcript binding	"ko:K07188|LIPE,HSL"	ko04024|cAMP signaling pathway; ko04152|AMPK signaling pathway; ko04371|Apelin signaling pathway; ko04910|Insulin signaling pathway; ko04923|Regulation of lipolysis in adipocytes; ko04925|Aldosterone synthesis and secretion	4550	XP_025011069.1	XP_025011069.1 hormone-sensitive lipase [Gallus gallus]	sp|Q9R101|LIPS_ICTTR	sp|Q9R101|LIPS_ICTTR Hormone-sensitive lipase OS=Ictidomys tridecemlineatus GN=LIPE PE=2 SV=1	_	_	_	_	_	PF06350.9|HSL_N|Hormone-sensitive lipase (HSL) N-terminus|ENSGALT00000103761|m.10180:23-221
ENSGALG00000052488	13.44466178	5.897960999	1.187373918	3.08E-23	3.49E-22	up	yes	12.7078509	14.4987948	13.12733964	6.353949087	5.68785752	5.65207639	14	10461813	10463512	+	TMEM186	protein_coding	--	GO:0016021|integral component of membrane	--	--	--	1700	XP_015150071.2	XP_015150071.2 transmembrane protein 186 [Gallus gallus]	sp|B3DI94|TM186_DANRE	sp|B3DI94|TM186_DANRE Transmembrane protein 186 OS=Danio rerio GN=tmem186 PE=2 SV=1	9031.ENSGALP00000019441	transmembrane protein 186	_	_	NOG85564	PF14640.3|TMEM223|Transmembrane protein 223|ENSGALT00000094927|m.9756:137-236
ENSGALG00000052512	2.484139959	1.159517745	1.092628673	0.000692855	0.001495225	up	yes	2.602555818	2.314860947	2.535003112	0.850560209	0.944932354	1.683060672	6	34153579	34156676	+	NPS	protein_coding	"GO:0007218|neuropeptide signaling pathway; GO:0008542|visual learning; GO:0010841|positive regulation of circadian sleep/wake cycle, wakefulness; GO:0032230|positive regulation of synaptic transmission, GABAergic; GO:0045760|positive regulation of action potential; GO:0051968|positive regulation of synaptic transmission, glutamatergic"	GO:0005576|extracellular region	--	--	--	1235	XP_010713140.2	XP_010713140.2 PREDICTED: neuropeptide S isoform X2 [Meleagris gallopavo]	sp|P0C0P6|NPS_HUMAN	sp|P0C0P6|NPS_HUMAN Neuropeptide S OS=Homo sapiens GN=NPS PE=3 SV=1	9031.ENSGALP00000040561	annotation not avaliable	_	_	NOG113114	PF14993.3|Neuropeptide_S|Neuropeptide S precursor protein|ENSGALT00000105078|m.5492:45-119
ENSGALG00000052541	2.190153068	0.906550711	1.263317288	8.11E-15	5.35E-14	up	yes	2.186891309	2.214639304	2.168928592	0.887751259	1.001922572	0.829978301	33	7394692	7400565	+	ENSGALG00000052541	protein_coding	GO:0007165|signal transduction; GO:0007179|transforming growth factor beta receptor signaling pathway; GO:0007186|G protein-coupled receptor signaling pathway; GO:0007548|sex differentiation; GO:0008584|male gonad development; GO:0008585|female gonad development; GO:1902613|negative regulation of anti-Mullerian hormone signaling pathway; GO:1990262|anti-Mullerian hormone signaling pathway	GO:0005887|integral component of plasma membrane	"GO:0005026|transforming growth factor beta receptor activity, type II; GO:0005524|ATP binding; GO:0038023|signaling receptor activity; GO:0042562|hormone binding; GO:0046872|metal ion binding; GO:1990272|anti-Mullerian hormone receptor activity"	--	--	4867	DAA79952.1	"DAA79952.1 TPA_inf: anti-Mullerian hormone type-2 receptor, partial [Gallus gallus]"	sp|Q62893|AMHR2_RAT	sp|Q62893|AMHR2_RAT Anti-Muellerian hormone type-2 receptor OS=Rattus norvegicus GN=Amhr2 PE=2 SV=1	9685.ENSFCAP00000005475	"anti-Mullerian hormone receptor, type II"	_	KOG3653	_	PF07714.14|Pkinase_Tyr|Protein tyrosine kinase|ENSGALT00000090962|m.15777:57-209;PF00069.22|Pkinase|Protein kinase domain|ENSGALT00000090962|m.15777:61-212
ENSGALG00000052546	0.928254979	0.205427476	2.122777774	1.19E-10	5.60E-10	up	yes	1.047624566	0.99530944	0.74183093	0.277508509	0.157562754	0.181211166	32	562790	573855	-	HIF3A	protein_coding	GO:0001525|angiogenesis; GO:0001666|response to hypoxia; GO:0006357|regulation of transcription by RNA polymerase II; GO:0006366|transcription by RNA polymerase II; GO:0006915|apoptotic process; GO:0045944|positive regulation of transcription by RNA polymerase II	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005739|mitochondrion; GO:0016607|nuclear speck	"GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity; GO:0003713|transcription coactivator activity; GO:0003714|transcription corepressor activity; GO:0046983|protein dimerization activity"	ko:K09096|HIF3A	--	2236	XP_025000263.1	XP_025000263.1 neuronal PAS domain-containing protein 1 isoform X2 [Gallus gallus]	sp|Q9JHS2|HIF3A_RAT	sp|Q9JHS2|HIF3A_RAT Hypoxia-inducible factor 3-alpha OS=Rattus norvegicus GN=Hif3a PE=1 SV=1	_	_	_	_	_	PF08447.9|PAS_3|PAS fold|ENSGALT00000098096|m.14459:237-322;PF14598.3|PAS_11|PAS domain|ENSGALT00000098096|m.14459:228-327;PF00989.22|PAS|PAS fold|ENSGALT00000098096|m.14459:89-148;PF00989.22|PAS|PAS fold|ENSGALT00000098096|m.14459:235-311
ENSGALG00000052635	4.549901529	1.986171046	1.191767323	2.50E-08	9.48E-08	up	yes	3.532363515	5.707442735	4.409898337	2.140670664	1.785102654	2.032739821	8	11753979	11755589	-	ENSGALG00000052635	protein_coding	--	--	--	--	--	1611	XP_019516334.1	XP_019516334.1 PREDICTED: uncharacterized protein LOC109392377 [Hipposideros armiger]	_	_	_	_	_	_	_	PF00075.21|RNase_H|RNase H|ENSGALT00000100336|m.7378:404-535;PF00078.24|RVT_1|Reverse transcriptase (RNA-dependent DNA polymerase)|ENSGALT00000100336|m.7378:1-154
ENSGALG00000052636	1.247498589	0.584971326	1.079664734	0.010582424	0.018634133	up	yes	1.233405644	1.193720998	1.315369124	0.556731958	0.702442691	0.49573933	11	12896393	12897460	-	ENSGALG00000052636	protein_coding	GO:0006310|DNA recombination; GO:0015074|DNA integration; GO:0044826|viral genome integration into host DNA; GO:0046718|viral entry into host cell; GO:0075713|establishment of integrated proviral latency	GO:0019028|viral capsid	GO:0003677|DNA binding; GO:0003887|DNA-directed DNA polymerase activity; GO:0003964|RNA-directed DNA polymerase activity; GO:0004190|aspartic-type endopeptidase activity; GO:0004523|RNA-DNA hybrid ribonuclease activity; GO:0005198|structural molecule activity; GO:0008270|zinc ion binding	--	--	1068	CAA42505.1	"CAA42505.1 pol, partial [Gallus gallus]"	sp|O92956|POL_RSVSB	sp|O92956|POL_RSVSB Gag-Pro-Pol polyprotein OS=Rous sarcoma virus (strain Schmidt-Ruppin B) GN=gag-pro-pol PE=1 SV=2	59729.ENSTGUP00000002330	similar to Pro-Pol	_	KOG0017	_	PF00665.23|rve|Integrase core domain|ENSGALT00000100264|m.6718:139-249;PF02022.16|Integrase_Zn|Integrase Zinc binding domain|ENSGALT00000100264|m.6718:88-124;PF00552.18|IN_DBD_C|Integrase DNA binding domain|ENSGALT00000100264|m.6718:312-350
ENSGALG00000052649	36.42608133	10.58637151	1.781797476	1.95E-24	2.36E-23	up	yes	33.74442452	35.1855744	40.34824507	12.53684385	10.88448162	8.33778905	1	48170395	48170775	+	H2B-V	protein_coding	GO:0042742|defense response to bacterium	GO:0000786|nucleosome; GO:0005634|nucleus	GO:0003677|DNA binding; GO:0046982|protein heterodimerization activity	ko:K11252|H2B	ko05034|Alcoholism; ko05203|Viral carcinogenesis; ko05322|Systemic lupus erythematosus	381	XP_003768757.1	XP_003768757.1 histone H2B type 2-E-like [Sarcophilus harrisii]	sp|Q5RCP8|H2B2E_PONAB	sp|Q5RCP8|H2B2E_PONAB Histone H2B type 2-E OS=Pongo abelii GN=HIST2H2BE PE=2 SV=3	9031.ENSGALP00000019169	Histone H2B 8 (H2B VIII); Core component of nucleosome. Nucleosomes wrap and compact DNA int [...] 	_	KOG1744	_	PF00125.21|Histone|Core histone H2A/H2B/H3/H4|ENSGALT00000092743|m.1213:10-101;PF00808.20|CBFD_NFYB_HMF|Histone-like transcription factor (CBF/NF-Y) and archaeal histone|ENSGALT00000092743|m.1213:42-99
ENSGALG00000052702	6.459547937	2.215353319	1.539630496	0.000110207	0.000268745	up	yes	6.586386138	7.914430505	4.877827168	1.85809291	2.677249746	2.110717303	9	12614245	12614532	+	ENSGALG00000052702	protein_coding	--	--	--	--	--	288	XP_023969843.1	XP_023969843.1 uncharacterized protein NCBP2-AS2-like [Chrysemys picta bellii]	_	_	_	_	_	_	_	_
ENSGALG00000052712	6.480013741	2.141563487	1.592836121	3.35E-33	6.23E-32	up	yes	6.478684226	5.867865584	7.093491412	2.106617706	2.011828264	2.306244493	22	4009355	4015124	-	ENSGALG00000052712	protein_coding	GO:0006556|S-adenosylmethionine biosynthetic process; GO:0006730|one-carbon metabolic process; GO:0032259|methylation; GO:0034214|protein hexamerization; GO:0051291|protein heterooligomerization; GO:1990830|cellular response to leukemia inhibitory factor	GO:0005829|cytosol; GO:0048269|methionine adenosyltransferase complex	GO:0004478|methionine adenosyltransferase activity; GO:0005524|ATP binding; GO:0042802|identical protein binding; GO:0046872|metal ion binding	ko:K00789|metK	ko00270|Cysteine and methionine metabolism; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko01230|Biosynthesis of amino acids	2064	XP_021230397.1	XP_021230397.1 S-adenosylmethionine synthase [Numida meleagris]	sp|P31153|METK2_HUMAN	sp|P31153|METK2_HUMAN S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens GN=MAT2A PE=1 SV=1	_	_	_	_	_	"PF00438.17|S-AdoMet_synt_N|S-adenosylmethionine synthetase, N-terminal domain|ENSGALT00000091604|m.4959:18-56;PF00438.17|S-AdoMet_synt_N|S-adenosylmethionine synthetase, N-terminal domain|ENSGALT00000091604|m.4959:187-240"
ENSGALG00000052743	5.506308063	2.613579799	1.072166356	4.39E-10	1.96E-09	up	yes	4.915786739	5.541548376	6.061589073	2.704256503	2.36946412	2.767018774	7	5748285	5750646	-	ARL4C	protein_coding	GO:0007264|small GTPase mediated signal transduction; GO:0032456|endocytic recycling	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0030175|filopodium	GO:0003924|GTPase activity; GO:0005525|GTP binding; GO:0043014|alpha-tubulin binding	ko:K07945|ARL4	--	1715	XP_005062049.1	XP_005062049.1 PREDICTED: ADP-ribosylation factor-like protein 4C isoform X1 [Ficedula albicollis]	sp|P56559|ARL4C_HUMAN	sp|P56559|ARL4C_HUMAN ADP-ribosylation factor-like protein 4C OS=Homo sapiens GN=ARL4C PE=1 SV=1	59729.ENSTGUP00000003188	ADP-ribosylation factor-like protein 4C (ADP-ribosylation factor-like protein 7)(ADP-ribosyl [...] 	COG1100	KOG0070	_	"PF00025.18|Arf|ADP-ribosylation factor family|ENSGALT00000104939|m.5751:31-200;PF08477.10|Roc|Ras of Complex, Roc, domain of DAPkinase|ENSGALT00000104939|m.5751:37-151;PF00071.19|Ras|Ras family|ENSGALT00000104939|m.5751:37-162;PF09439.7|SRPRB|Signal recognition particle receptor beta subunit|ENSGALT00000104939|m.5751:36-165;PF01926.20|MMR_HSR1|50S ribosome-binding GTPase|ENSGALT00000104939|m.5751:37-149"
ENSGALG00000052753	3.158322531	1.157977623	1.439706572	5.57E-09	2.24E-08	up	yes	1.960832514	3.741665036	3.772470041	1.144169171	1.113541466	1.216222233	9	16013530	16015842	+	ENSGALG00000052753	protein_coding	--	--	--	--	--	2096	XP_015147039.1	XP_015147039.1 von Willebrand factor A domain-containing protein 5B2 isoform X2 [Gallus gallus]	sp|Q8N398|VW5B2_HUMAN	sp|Q8N398|VW5B2_HUMAN von Willebrand factor A domain-containing protein 5B2 OS=Homo sapiens GN=VWA5B2 PE=2 SV=2	_	_	_	_	_	PF13757.3|VIT_2|Vault protein inter-alpha-trypsin domain|ENSGALT00000096343|m.9092:2-78;PF08487.7|VIT|Vault protein inter-alpha-trypsin domain|ENSGALT00000096343|m.9092:15-80
ENSGALG00000052768	46.88731232	22.18010979	1.079588439	2.32E-19	2.09E-18	up	yes	50.53924551	47.45993212	42.66275932	18.35396558	22.49522321	25.69114057	KZ626830.1	2805	12180	-	LDLR	protein_coding	GO:0006869|lipid transport; GO:0006897|endocytosis; GO:0008203|cholesterol metabolic process	GO:0005764|lysosome; GO:0005769|early endosome; GO:0005770|late endosome; GO:0005794|Golgi apparatus; GO:0005886|plasma membrane; GO:0005905|clathrin-coated pit; GO:0009986|cell surface; GO:0016021|integral component of membrane; GO:0034362|low-density lipoprotein particle	GO:0005509|calcium ion binding	--	--	906	NP_989783.1	NP_989783.1 low density lipoprotein receptor precursor [Gallus gallus]	sp|P35950|LDLR_CRIGR	sp|P35950|LDLR_CRIGR Low-density lipoprotein receptor OS=Cricetulus griseus GN=LDLR PE=3 SV=2	9258.ENSOANP00000028364	low density lipoprotein receptor	_	KOG1215	_	PF00058.14|Ldl_recept_b|Low-density lipoprotein receptor repeat class B|ENSGALT00000103704|m.9613:5-46
ENSGALG00000052786	1.66135162	0.743063507	1.150171841	4.55E-08	1.68E-07	up	yes	1.528641282	1.663958579	1.791455	0.636918257	0.953363601	0.638908662	4	11216793	11249616	-	ENSGALG00000052786	protein_coding	--	GO:0005737|cytoplasm; GO:0005925|focal adhesion; GO:0015629|actin cytoskeleton	GO:0046872|metal ion binding; GO:0051015|actin filament binding	--	--	4481	XP_015134034.1	XP_015134034.1 zinc finger protein 185 isoform X1 [Gallus gallus]	sp|Q62394|ZN185_MOUSE	sp|Q62394|ZN185_MOUSE Zinc finger protein 185 OS=Mus musculus GN=Znf185 PE=1 SV=1	9031.ENSGALP00000012090	similar to P1-A	_	KOG1704	_	_
ENSGALG00000052818	0.696929552	0.245471428	1.468404503	0.001513087	0.003097701	up	yes	0.704803225	0.806149245	0.579836185	0.307528129	0.156098376	0.27278778	11	12899315	12901183	-	ENSGALG00000052818	protein_coding	GO:0046797|viral procapsid maturation	GO:0019028|viral capsid; GO:0044095|host cell nucleoplasm; GO:0044196|host cell nucleolus	GO:0003676|nucleic acid binding; GO:0004190|aspartic-type endopeptidase activity; GO:0008270|zinc ion binding; GO:0039660|structural constituent of virion	--	--	1869	XP_015137376.2	XP_015137376.2 endogenous retrovirus group K member 113 Gag polyprotein-like [Gallus gallus]	sp|P0C776|GAG_RSVSA	sp|P0C776|GAG_RSVSA Gag-Pro polyprotein OS=Avian leukosis virus RSA GN=gag-pro PE=3 SV=1	_	_	_	_	_	PF02813.11|Retro_M|Retroviral M domain|ENSGALT00000095705|m.6719:2-87;PF00607.17|Gag_p24|gag gene protein p24 (core nucleocapsid protein)|ENSGALT00000095705|m.6719:308-494;PF00098.20|zf-CCHC|Zinc knuckle|ENSGALT00000095705|m.6719:544-560
ENSGALG00000052829	0.32796317	0.812404428	-1.282981995	1.86E-05	5.06E-05	down	yes	0.249602506	0.43007062	0.304216385	0.802738386	0.858836847	0.775638051	17	918451	928380	-	MAMDC4	protein_coding	GO:0015031|protein transport	GO:0016021|integral component of membrane	--	--	--	4222	XP_015135101.1	XP_015135101.1 apical endosomal glycoprotein isoform X2 [Gallus gallus]	sp|A2AJA7|AEGP_MOUSE	sp|A2AJA7|AEGP_MOUSE Apical endosomal glycoprotein OS=Mus musculus GN=Mamdc4 PE=3 SV=1	9031.ENSGALP00000014614	annotation not avaliable	_	KOG1095;KOG3627	_	"PF00629.20|MAM|MAM domain, meprin/A5/mu|ENSGALT00000095794|m.11686:179-338;PF00629.20|MAM|MAM domain, meprin/A5/mu|ENSGALT00000095794|m.11686:390-538;PF00629.20|MAM|MAM domain, meprin/A5/mu|ENSGALT00000095794|m.11686:597-744;PF00629.20|MAM|MAM domain, meprin/A5/mu|ENSGALT00000095794|m.11686:758-908;PF00629.20|MAM|MAM domain, meprin/A5/mu|ENSGALT00000095794|m.11686:914-1067;PF00629.20|MAM|MAM domain, meprin/A5/mu|ENSGALT00000095794|m.11686:1072-1233;PF00057.15|Ldl_recept_a|Low-density lipoprotein receptor domain class A|ENSGALT00000095794|m.11686:347-384;PF00057.15|Ldl_recept_a|Low-density lipoprotein receptor domain class A|ENSGALT00000095794|m.11686:558-593"
ENSGALG00000052842	22.75842978	59.14180517	-1.377387397	3.12E-59	1.50E-57	down	yes	24.83269745	22.41836087	21.02423102	51.07214155	62.55873832	63.79453563	11	18613425	18695227	-	ANKRD11	protein_coding	GO:0001701|in utero embryonic development; GO:0001894|tissue homeostasis; GO:0035264|multicellular organism growth; GO:0042475|odontogenesis of dentin-containing tooth; GO:0048705|skeletal system morphogenesis; GO:0060325|face morphogenesis; GO:0060348|bone development	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005829|cytosol; GO:0005886|plasma membrane	--	ko:K21436|--	--	9578	XP_015148160.1	XP_015148160.1 ankyrin repeat domain-containing protein 11 [Gallus gallus]	sp|Q6UB99|ANR11_HUMAN	sp|Q6UB99|ANR11_HUMAN Ankyrin repeat domain-containing protein 11 OS=Homo sapiens GN=ANKRD11 PE=1 SV=3	_	_	_	_	_	PF12796.4|Ank_2|Ankyrin repeats (3 copies)|ENSGALT00000105125|m.6898:162-230;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000105125|m.6898:168-198;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000105125|m.6898:201-229;PF00023.27|Ank|Ankyrin repeat|ENSGALT00000105125|m.6898:233-263;PF13857.3|Ank_5|Ankyrin repeats (many copies)|ENSGALT00000105125|m.6898:220-274;PF13637.3|Ank_4|Ankyrin repeats (many copies)|ENSGALT00000105125|m.6898:170-220;PF13606.3|Ank_3|Ankyrin repeat|ENSGALT00000105125|m.6898:201-228
ENSGALG00000052859	0.760807929	2.183050783	-1.508495902	0.012204523	0.021239703	down	yes	0.944500834	0.235747688	1.102175266	1.768802404	2.432026981	2.348322963	18	1079537	1093969	+	ENSGALG00000052859	protein_coding	GO:0003341|cilium movement; GO:0030030|cell projection organization	GO:0005737|cytoplasm; GO:0005874|microtubule; GO:0005930|axoneme; GO:0030286|dynein complex; GO:0031514|motile cilium	"GO:0005524|ATP binding; GO:0008569|ATP-dependent microtubule motor activity, minus-end-directed; GO:0045503|dynein light chain binding; GO:0045505|dynein intermediate chain binding; GO:0051959|dynein light intermediate chain binding"	ko:K10408|DNAH	ko05016|Huntington's disease	2622	XP_415585.5	"XP_415585.5 dynein heavy chain 9, axonemal [Gallus gallus]"	sp|Q9NYC9|DYH9_HUMAN	"sp|Q9NYC9|DYH9_HUMAN Dynein heavy chain 9, axonemal OS=Homo sapiens GN=DNAH9 PE=1 SV=3"	_	_	_	_	_	"PF08393.10|DHC_N2|Dynein heavy chain, N-terminal region 2|ENSGALT00000105274|m.12530:314-720;PF12774.4|AAA_6|Hydrolytic ATP binding site of dynein motor region D1|ENSGALT00000105274|m.12530:854-873"
ENSGALG00000052876	1.218988913	2.7837853	-1.184749255	2.53E-06	7.69E-06	down	yes	1.348978216	1.424263679	0.883724843	3.206867299	2.784953279	2.359535323	16	1714898	1717308	-	ENSGALG00000052876	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated"	GO:0016607|nuclear speck	GO:0003677|DNA binding; GO:0003700|DNA-binding transcription factor activity; GO:0046872|metal ion binding	ko:K09228|KRAB	--	1953	XP_025011594.1	XP_025011594.1 zinc finger protein 501 isoform X1 [Gallus gallus]	sp|Q6ZSS3|ZN621_HUMAN	sp|Q6ZSS3|ZN621_HUMAN Zinc finger protein 621 OS=Homo sapiens GN=ZNF621 PE=2 SV=1	_	_	_	_	_	"PF00096.23|zf-C2H2|Zinc finger, C2H2 type|ENSGALT00000095054|m.11309:333-354;PF00096.23|zf-C2H2|Zinc finger, C2H2 type|ENSGALT00000095054|m.11309:416-438;PF00096.23|zf-C2H2|Zinc finger, C2H2 type|ENSGALT00000095054|m.11309:444-466;PF00096.23|zf-C2H2|Zinc finger, C2H2 type|ENSGALT00000095054|m.11309:528-550;PF13894.3|zf-C2H2_4|C2H2-type zinc finger|ENSGALT00000095054|m.11309:444-466;PF13894.3|zf-C2H2_4|C2H2-type zinc finger|ENSGALT00000095054|m.11309:528-550;PF01352.24|KRAB|KRAB box|ENSGALT00000095054|m.11309:143-183;PF13912.3|zf-C2H2_6|C2H2-type zinc finger|ENSGALT00000095054|m.11309:584-602"
ENSGALG00000052918	0.911734368	0.197978299	2.147918042	1.75E-08	6.73E-08	up	yes	1.134044963	0.785289265	0.815868877	0.221183904	0.224255319	0.148495675	28	877381	880062	+	ENSGALG00000052918	protein_coding	--	--	--	"ko:K06261|GP1BA,CD42b"	ko04512|ECM-receptor interaction; ko04611|Platelet activation; ko04640|Hematopoietic cell lineage	2509	XP_004948723.1	XP_004948723.1 platelet glycoprotein Ib alpha chain-like [Gallus gallus]	_	_	_	_	_	_	_	PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000103555|m.9564:62-116;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000103555|m.9564:104-162;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000103555|m.9564:126-186;PF13855.3|LRR_8|Leucine rich repeat|ENSGALT00000103555|m.9564:150-210
ENSGALG00000052930	8.560546661	3.984213308	1.101475847	1.88E-17	1.49E-16	up	yes	9.348419035	8.116476992	8.216743957	4.065570811	4.335022323	3.552046792	KZ626839.1	845139	856540	-	ENSGALG00000052930	protein_coding	GO:0000165|MAPK cascade; GO:0006397|mRNA processing; GO:0043066|negative regulation of apoptotic process; GO:0071222|cellular response to lipopolysaccharide; GO:1904247|positive regulation of polynucleotide adenylyltransferase activity	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0016607|nuclear speck; GO:0042405|nuclear inclusion body; GO:0070062|extracellular exosome; GO:0097136|Bcl-2 family protein complex; GO:1990904|ribonucleoprotein complex	GO:0003723|RNA binding; GO:0042802|identical protein binding; GO:0043621|protein self-association; GO:0046982|protein heterodimerization activity; GO:0070063|RNA polymerase binding; GO:0097718|disordered domain specific binding	"ko:K14396|PABPN1,PABP2"	ko03015|mRNA surveillance pathway; ko05164|Influenza A	1779	XP_025002313.1	XP_025002313.1 polyadenylate-binding protein 2 isoform X1 [Gallus gallus]	sp|Q28165|PABP2_BOVIN	sp|Q28165|PABP2_BOVIN Polyadenylate-binding protein 2 OS=Bos taurus GN=PABPN1 PE=1 SV=3	9258.ENSOANP00000014672	"poly(A) binding protein, nuclear 1"	_	KOG4209	_	"PF00076.19|RRM_1|RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)|ENSGALT00000101557|m.10018:347-410"
ENSGALG00000052932	1.484931918	8.325983877	-2.479272704	4.59E-115	8.66E-113	down	yes	1.573524349	1.327732628	1.553538777	8.015156869	8.761197122	8.20159764	4	49738482	49832032	-	SHROOM3	protein_coding	GO:0000902|cell morphogenesis; GO:0001843|neural tube closure; GO:0002064|epithelial cell development; GO:0007389|pattern specification process; GO:0008360|regulation of cell shape; GO:0043482|cellular pigment accumulation; GO:0045176|apical protein localization	GO:0005737|cytoplasm; GO:0005856|cytoskeleton; GO:0005874|microtubule; GO:0005912|adherens junction; GO:0016324|apical plasma membrane; GO:0043296|apical junction complex	GO:0051015|actin filament binding	ko:K18625|SHROOM	--	5994	XP_420592.4	XP_420592.4 protein Shroom3 isoform X1 [Gallus gallus]	sp|Q8TF72|SHRM3_HUMAN	sp|Q8TF72|SHRM3_HUMAN Protein Shroom3 OS=Homo sapiens GN=SHROOM3 PE=1 SV=2	9031.ENSGALP00000018701	shroom family member 3	_	_	NOG72784	PF08687.8|ASD2|Apx/Shroom domain ASD2|ENSGALT00000107012|m.659:1675-1960;PF08688.7|ASD1|Apx/Shroom domain ASD1|ENSGALT00000107012|m.659:850-1031
ENSGALG00000052964	0.710368004	0.170772963	1.99455518	4.56E-06	1.34E-05	up	yes	0.439641962	0.854216551	0.8372455	0.140564948	0.199958307	0.171795635	2	40639239	40641635	-	ENSGALG00000052964	protein_coding	--	--	--	--	--	2397	POI32623.1	"POI32623.1 hypothetical protein CIB84_003625, partial [Bambusicola thoracicus]"	_	_	_	_	_	_	_	_
ENSGALG00000052994	0.723526161	0.152739377	2.172285048	6.37E-07	2.08E-06	up	yes	0.88986029	0.444218783	0.83649941	0.185163888	0.089856126	0.183198117	27	7595502	7600252	-	C17orf113	protein_coding	--	GO:0016021|integral component of membrane	--	--	--	2783	XP_004948666.1	XP_004948666.1 transmembrane protein C17orf113 homolog isoform X1 [Gallus gallus]	sp|A0A1B0GUU1|CQ113_HUMAN	sp|A0A1B0GUU1|CQ113_HUMAN Transmembrane protein C17orf113 OS=Homo sapiens GN=C17orf113 PE=3 SV=1	_	_	_	_	_	_
ENSGALG00000053000	11.54027625	35.60471949	-1.62454627	1.01E-119	2.18E-117	down	yes	10.63463335	12.4700605	11.5161349	34.85576033	36.01947882	35.93891932	4	89068635	89132168	-	C20orf194	protein_coding	--	--	--	--	--	5465	XP_420883.4	XP_420883.4 uncharacterized protein C20orf194 homolog isoform X1 [Gallus gallus]	sp|Q5TEA3|CT194_HUMAN	sp|Q5TEA3|CT194_HUMAN Uncharacterized protein C20orf194 OS=Homo sapiens GN=C20orf194 PE=1 SV=1	9031.ENSGALP00000025771	chromosome 20 open reading frame 194	_	_	NOG69297	_
ENSGALG00000053068	6.835731533	3.100151858	1.138219692	2.53E-07	8.62E-07	up	yes	6.705273974	5.578794555	8.223126069	3.82798443	2.46383253	3.008638615	33	7715050	7717518	-	SMUG1	protein_coding	GO:0006281|DNA repair; GO:0006284|base-excision repair	GO:0005730|nucleolus; GO:0031981|nuclear lumen	GO:0000702|oxidized base lesion DNA N-glycosylase activity; GO:0000703|oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity; GO:0003697|single-stranded DNA binding; GO:0004844|uracil DNA N-glycosylase activity; GO:0017065|single-strand selective uracil DNA N-glycosylase activity; GO:0019104|DNA N-glycosylase activity	ko:K10800|SMUG1	ko03410|Base excision repair	1108	XP_015155839.1	XP_015155839.1 single-strand selective monofunctional uracil DNA glycosylase isoform X1 [Gallus gallus]	sp|Q6P5C5|SMUG1_MOUSE	sp|Q6P5C5|SMUG1_MOUSE Single-strand selective monofunctional uracil DNA glycosylase OS=Mus musculus GN=Smug1 PE=1 SV=1	9031.ENSGALP00000023350	single-strand-selective monofunctional uracil-DNA glycosylase 1	_	_	NOG79853	_
ENSGALG00000053089	51.48421276	6.944291109	2.888434937	9.37E-61	4.75E-59	up	yes	58.01342134	49.94993428	46.48928266	7.474079673	5.964061677	7.394731977	2	148924533	148924829	-	ENSGALG00000053089	protein_coding	--	GO:0005882|intermediate filament	GO:0005200|structural constituent of cytoskeleton	--	--	297	XP_003643694.1	XP_003643694.1 feather keratin 1-like [Gallus gallus]	sp|P02451|KRFT_LARNO	sp|P02451|KRFT_LARNO Feather keratin OS=Larus novaehollandiae PE=1 SV=1	9031.ENSGALP00000034768	annotation not avaliable	_	_	NOG231326	_
ENSGALG00000053099	58.83320878	5.18270846	3.502316786	3.89E-87	3.61E-85	up	yes	65.81950861	59.05539105	51.62472667	5.672292609	5.122076499	4.753756271	2	148904630	148904926	-	ENSGALG00000053099	protein_coding	--	GO:0005882|intermediate filament	GO:0005200|structural constituent of cytoskeleton	--	--	297	XP_025003978.1	XP_025003978.1 feather keratin 1-like [Gallus gallus]	sp|P02451|KRFT_LARNO	sp|P02451|KRFT_LARNO Feather keratin OS=Larus novaehollandiae PE=1 SV=1	9031.ENSGALP00000034768	annotation not avaliable	_	_	NOG231326	_
ENSGALG00000053100	22.87213089	7.068895789	1.692625166	4.01E-90	4.04E-88	up	yes	21.07088337	23.45875027	24.08675902	7.617724075	6.702998309	6.885964983	20	5465776	5471265	+	FITM2	protein_coding	GO:0007010|cytoskeleton organization; GO:0008654|phospholipid biosynthetic process; GO:0010866|regulation of triglyceride biosynthetic process; GO:0010890|positive regulation of sequestering of triglyceride; GO:0022604|regulation of cell morphogenesis; GO:0030730|sequestering of triglyceride; GO:0034389|lipid droplet organization; GO:0035356|cellular triglyceride homeostasis	GO:0005739|mitochondrion; GO:0005789|endoplasmic reticulum membrane; GO:0030176|integral component of endoplasmic reticulum membrane	--	--	--	3796	XP_417378.2	XP_417378.2 fat storage-inducing transmembrane protein 2 isoform X1 [Gallus gallus]	sp|P59266|FITM2_MOUSE	sp|P59266|FITM2_MOUSE Fat storage-inducing transmembrane protein 2 OS=Mus musculus GN=Fitm2 PE=1 SV=1	9031.ENSGALP00000006842	chromosome 20 open reading frame 142	_	KOG3750	_	PF10261.6|Scs3p|Inositol phospholipid synthesis and fat-storage-inducing TM|ENSGALT00000093761|m.3049:175-307
ENSGALG00000053244	1.016916514	0.411649863	1.284201507	0.000219285	0.000510819	up	yes	1.239229594	1.030916321	0.780603627	0.457169852	0.40528391	0.372495827	33	6338302	6341663	+	ENSGALG00000053244	protein_coding	--	GO:0005634|nucleus; GO:0005737|cytoplasm	GO:0004518|nuclease activity; GO:0046872|metal ion binding	--	--	2211	XP_015128486.2	XP_015128486.2 uncharacterized protein LOC101751955 isoform X1 [Gallus gallus]	sp|B0BN95|HARB1_RAT	sp|B0BN95|HARB1_RAT Putative nuclease HARBI1 OS=Rattus norvegicus GN=Harbi1 PE=2 SV=1	9031.ENSGALP00000021804	hypothetical protein LOC772153	_	KOG4585	_	PF13359.3|DDE_Tnp_4|DDE superfamily endonuclease|ENSGALT00000093671|m.15339:184-334
ENSGALG00000053285	2.280745523	0.535936864	2.069011178	3.92E-13	2.27E-12	up	yes	2.341826182	2.518309187	1.982101199	0.362136956	0.596873937	0.648799698	25	3027026	3029971	+	ENSGALG00000053285	protein_coding	"GO:0001657|ureteric bud development; GO:0003148|outflow tract septum morphogenesis; GO:0003183|mitral valve morphogenesis; GO:0003184|pulmonary valve morphogenesis; GO:0003281|ventricular septum development; GO:0006351|transcription, DNA-templated; GO:0006955|immune response; GO:0007179|transforming growth factor beta receptor signaling pathway; GO:0007352|zygotic specification of dorsal/ventral axis; GO:0008285|negative regulation of cell population proliferation; GO:0010991|negative regulation of SMAD protein complex assembly; GO:0030279|negative regulation of ossification; GO:0030509|BMP signaling pathway; GO:0030512|negative regulation of transforming growth factor beta receptor signaling pathway; GO:0030514|negative regulation of BMP signaling pathway; GO:0031589|cell-substrate adhesion; GO:0034616|response to laminar fluid shear stress; GO:0035904|aorta development; GO:0043066|negative regulation of apoptotic process; GO:0043627|response to estrogen; GO:0045444|fat cell differentiation; GO:0060394|negative regulation of pathway-restricted SMAD protein phosphorylation; GO:0060976|coronary vasculature development; GO:1902895|positive regulation of pri-miRNA transcription by RNA polymerase II"	GO:0005634|nucleus; GO:0005667|transcription factor complex; GO:0005737|cytoplasm; GO:0005794|Golgi apparatus; GO:0005829|cytosol; GO:0016604|nuclear body; GO:0032991|protein-containing complex	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0003682|chromatin binding; GO:0003700|DNA-binding transcription factor activity; GO:0030617|transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity; GO:0031625|ubiquitin protein ligase binding; GO:0034713|type I transforming growth factor beta receptor binding; GO:0042802|identical protein binding; GO:0044212|transcription regulatory region DNA binding; GO:0046872|metal ion binding; GO:0070410|co-SMAD binding; GO:0070411|I-SMAD binding; GO:0070412|R-SMAD binding; GO:0070698|type I activin receptor binding"	ko:K04677|SMAD6	ko04350|TGF-beta signaling pathway	2025	XP_024999234.1	XP_024999234.1 mothers against decapentaplegic homolog 6-like [Gallus gallus]	sp|O43541|SMAD6_HUMAN	sp|O43541|SMAD6_HUMAN Mothers against decapentaplegic homolog 6 OS=Homo sapiens GN=SMAD6 PE=1 SV=2	59729.ENSTGUP00000004327	hypothetical protein LOC100221167	_	KOG3701	_	PF03166.11|MH2|MH2 domain|ENSGALT00000099914|m.7114:183-344;PF03165.13|MH1|MH1 domain|ENSGALT00000099914|m.7114:37-131
ENSGALG00000053299	14.16391972	4.130377155	1.775404686	4.01E-51	1.49E-49	up	yes	14.96598697	13.37525677	14.15051541	4.600457825	3.333758096	4.456915544	33	6686124	6702978	-	KCNC3	protein_coding	GO:0007420|brain development; GO:0009636|response to toxic substance; GO:0009642|response to light intensity; GO:0010996|response to auditory stimulus; GO:0014075|response to amine; GO:0021549|cerebellum development; GO:0021759|globus pallidus development; GO:0034765|regulation of ion transmembrane transport; GO:0034767|positive regulation of ion transmembrane transport; GO:0035690|cellular response to drug; GO:0035864|response to potassium ion; GO:0051260|protein homooligomerization; GO:0051262|protein tetramerization; GO:0071774|response to fibroblast growth factor; GO:0071805|potassium ion transmembrane transport; GO:1901379|regulation of potassium ion transmembrane transport; GO:1901381|positive regulation of potassium ion transmembrane transport; GO:1903818|positive regulation of voltage-gated potassium channel activity; GO:1990089|response to nerve growth factor	GO:0008076|voltage-gated potassium channel complex; GO:0009986|cell surface; GO:0016020|membrane; GO:0030425|dendrite; GO:0030673|axolemma; GO:0032589|neuron projection membrane; GO:0032590|dendrite membrane; GO:0032809|neuronal cell body membrane; GO:0043025|neuronal cell body	GO:0005251|delayed rectifier potassium channel activity; GO:0019894|kinesin binding; GO:0044325|ion channel binding	ko:K04889|KCNC3	--	2852	XP_025001249.1	XP_025001249.1 potassium voltage-gated channel subfamily C member 1-like [Gallus gallus]	sp|P25122|KCNC1_RAT	sp|P25122|KCNC1_RAT Potassium voltage-gated channel subfamily C member 1 OS=Rattus norvegicus GN=Kcnc1 PE=1 SV=1	_	_	_	_	_	PF00520.28|Ion_trans|Ion transport protein|ENSGALT00000101740|m.15426:178-433;PF02214.19|BTB_2|BTB/POZ domain|ENSGALT00000101740|m.15426:10-104;PF07885.13|Ion_trans_2|Ion channel|ENSGALT00000101740|m.15426:342-426
ENSGALG00000053318	0.518320251	3.308579688	-2.651081301	3.64E-32	6.47E-31	down	yes	0.623242504	0.456961945	0.474756304	2.746926074	4.249275544	2.929537445	24	280977	286309	-	ENSGALG00000053318	protein_coding	GO:0001764|neuron migration; GO:0007411|axon guidance; GO:0016199|axon midline choice point recognition; GO:0035385|Roundabout signaling pathway; GO:0061642|chemoattraction of axon; GO:0061643|chemorepulsion of axon; GO:0071679|commissural neuron axon guidance	GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0030424|axon	--	ko:K06755|ROBO3	ko04360|Axon guidance	1826	XP_015153567.1	XP_015153567.1 roundabout homolog 3 isoform X5 [Gallus gallus]	sp|Q9Z2I4|ROBO3_MOUSE	sp|Q9Z2I4|ROBO3_MOUSE Roundabout homolog 3 OS=Mus musculus GN=Robo3 PE=1 SV=2	9031.ENSGALP00000001377	annotation not avaliable	_	KOG4222	_	_
ENSGALG00000053332	3.077790163	6.461277416	-1.067475811	7.34E-09	2.93E-08	down	yes	2.835738614	3.624492106	2.773139768	6.601747802	6.350252212	6.431832234	14	14571954	14578596	+	ENSGALG00000053332	protein_coding	--	--	--	--	--	1375	XP_015732867.1	XP_015732867.1 PREDICTED: uncharacterized protein C16orf59 homolog isoform X1 [Coturnix japonica]	sp|Q7L2K0|CP059_HUMAN	sp|Q7L2K0|CP059_HUMAN Uncharacterized protein C16orf59 OS=Homo sapiens GN=C16orf59 PE=1 SV=1	_	_	_	_	_	PF15764.2|DUF4693|Domain of unknown function (DUF4693)|ENSGALT00000097214|m.10087:141-430
ENSGALG00000053365	4.178632175	1.625051046	1.357143523	5.23E-22	5.53E-21	up	yes	4.823191231	3.54470849	4.167996805	1.647359287	1.610623849	1.617170001	KZ626835.1	1195343	1201906	+	ENSGALG00000053365	protein_coding	GO:0022008|neurogenesis	--	GO:0046872|metal ion binding	--	--	4632	XP_025002031.1	XP_025002031.1 dentin sialophosphoprotein-like [Gallus gallus]	sp|Q9QY66|ZNHI2_MOUSE	sp|Q9QY66|ZNHI2_MOUSE Zinc finger HIT domain-containing protein 2 OS=Mus musculus GN=Znhit2 PE=2 SV=2	_	_	_	_	_	PF08017.8|Fibrinogen_BP|Fibrinogen binding protein|ENSGALT00000103964|m.9689:264-470;PF04438.13|zf-HIT|HIT zinc finger|ENSGALT00000103964|m.9689:3-31
ENSGALG00000053391	1.000063127	2.699452133	-1.423555699	1.17E-08	4.56E-08	down	yes	0.664871787	1.401518143	0.933799451	3.016714461	2.514501083	2.567140857	25	3664866	3671707	+	ENSGALG00000053391	protein_coding	--	--	GO:0005509|calcium ion binding	--	--	2536	POI34308.1	POI34308.1 hypothetical protein CIB84_001942 [Bambusicola thoracicus]	sp|Q95LL8|EFC12_MACFA	sp|Q95LL8|EFC12_MACFA EF-hand calcium-binding domain-containing protein 12 OS=Macaca fascicularis GN=EFCAB12 PE=2 SV=1	9031.ENSGALP00000030793	EF-hand domain-containing protein C3orf25 	_	_	NOG70703	PF14908.3|DUF4496|Domain of unknown function (DUF4496)|ENSGALT00000100001|m.7292:38-174
ENSGALG00000053552	21.14175257	10.50209214	1.00872738	1.54E-14	9.90E-14	up	yes	20.90916234	21.98174477	20.5343506	10.52692442	11.45007316	9.529278825	17	5837944	5838933	-	IER5L	protein_coding	--	--	--	--	--	819	XP_015135201.1	XP_015135201.1 immediate early response gene 5-like protein [Gallus gallus]	sp|Q6PBC9|IER5L_XENTR	sp|Q6PBC9|IER5L_XENTR Immediate early response gene 5-like protein OS=Xenopus tropicalis GN=ier5l PE=2 SV=1	10141.ENSCPOP00000013919	immediate early response 5-like	_	_	NOG45187	PF05760.9|IER|Immediate early response protein (IER)|ENSGALT00000099080|m.12042:1-185;PF05760.9|IER|Immediate early response protein (IER)|ENSGALT00000099080|m.12042:197-272
ENSGALG00000053560	0.365258899	0.837268183	-1.174932408	0.005334701	0.00992902	down	yes	0.239625974	0.409952601	0.446198122	0.911363745	0.926651702	0.673789103	3	105798126	105833957	-	FBXO16	protein_coding	--	--	--	ko:K10299|FBXO16	--	1699	XP_004935940.3	XP_004935940.3 F-box only protein 16 [Gallus gallus]	sp|Q8IX29|FBX16_HUMAN	sp|Q8IX29|FBX16_HUMAN F-box only protein 16 OS=Homo sapiens GN=FBXO16 PE=2 SV=1	_	_	_	_	_	PF12937.4|F-box-like|F-box-like|ENSGALT00000102996|m.13250:105-149;PF00646.30|F-box|F-box domain|ENSGALT00000102996|m.13250:105-147
ENSGALG00000053571	0.113523937	0.897900613	-2.877743732	5.09E-09	2.06E-08	down	yes	0.143247184	0.070019306	0.127305322	0.754350361	0.94422896	0.995122518	16	1614883	1617893	+	ENSGALG00000053571	protein_coding	--	--	--	--	--	2207	XP_025011582.1	XP_025011582.1 scavenger receptor cysteine-rich type 1 protein M130-like isoform X2 [Gallus gallus]	_	_	9031.ENSGALP00000002137	annotation not avaliable	_	_	NOG83796	PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000095288|m.11299:31-127;PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000095288|m.11299:133-225;PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000095288|m.11300:69-163;PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000095288|m.11301:34-131
ENSGALG00000053575	20.363993	8.750291884	1.21767791	1.63E-24	1.98E-23	up	yes	22.13911307	20.31757519	18.63529073	7.966725155	8.493260151	9.790890344	33	5023150	5027892	+	DAZAP2	protein_coding	--	GO:0005737|cytoplasm; GO:0016607|nuclear speck; GO:0032991|protein-containing complex	GO:0042802|identical protein binding; GO:0050699|WW domain binding	--	--	1161	XP_025001426.1	XP_025001426.1 DAZ-associated protein 2 [Gallus gallus]	sp|Q3T0K9|DAZP2_BOVIN	sp|Q3T0K9|DAZP2_BOVIN DAZ-associated protein 2 OS=Bos taurus GN=DAZAP2 PE=2 SV=1	_	_	_	_	_	PF11029.5|DAZAP2|DAZ associated protein 2 (DAZAP2)|ENSGALT00000094098|m.15062:74-206
ENSGALG00000053585	2.120068434	0.442632192	2.234488682	2.29E-11	1.14E-10	up	yes	2.277535393	2.324307644	1.758362264	0.254691863	0.523412807	0.549791905	14	15415290	15419040	+	ENSGALG00000053585	protein_coding	"GO:0006123|mitochondrial electron transport, cytochrome c to oxygen; GO:0009060|aerobic respiration"	GO:0005739|mitochondrion; GO:0005751|mitochondrial respiratory chain complex IV	GO:0004129|cytochrome-c oxidase activity; GO:0030234|enzyme regulator activity	ko:K02266|COX6A	ko00190|Oxidative phosphorylation; ko01100|Metabolic pathways; ko04260|Cardiac muscle contraction; ko04932|Non-alcoholic fatty liver disease (NAFLD); ko05010|Alzheimer's disease; ko05012|Parkinson's disease; ko05016|Huntington's disease	1712	XP_015733007.1	"XP_015733007.1 PREDICTED: cytochrome c oxidase subunit 6A2, mitochondrial-like [Coturnix japonica]"	sp|P10817|CX6A2_RAT	"sp|P10817|CX6A2_RAT Cytochrome c oxidase subunit 6A2, mitochondrial (Fragment) OS=Rattus norvegicus GN=Cox6a2 PE=1 SV=3"	28377.ENSACAP00000002748	annotation not avaliable	_	KOG3469	_	PF02046.12|COX6A|Cytochrome c oxidase subunit VIa|ENSGALT00000092446|m.10171:64-146
ENSGALG00000053641	3.614037139	1.470053394	1.291948517	2.39E-05	6.39E-05	up	yes	3.802449729	3.729348347	3.310313342	1.987538308	0.878876281	1.543745593	25	3742770	3744406	-	ENSGALG00000053641	protein_coding	"GO:0006351|transcription, DNA-templated; GO:0032922|circadian regulation of gene expression; GO:0045475|locomotor rhythm; GO:0045892|negative regulation of transcription, DNA-templated"	GO:0005634|nucleus; GO:0016605|PML body	GO:0001046|core promoter sequence-specific DNA binding; GO:0070888|E-box binding	ko:K21599|--	--	1067	XP_015154127.2	XP_015154127.2 circadian-associated transcriptional repressor isoform X2 [Gallus gallus]	sp|Q3TQ03|CIART_MOUSE	sp|Q3TQ03|CIART_MOUSE Circadian-associated transcriptional repressor OS=Mus musculus GN=Ciart PE=1 SV=1	_	_	_	_	_	PF15673.2|DUF4664|Domain of unknown function (DUF4664)|ENSGALT00000106655|m.7322:51-129
ENSGALG00000053652	5.73709887	0.341945077	4.029411657	0.00048585	0.001074401	up	yes	6.158698726	5.644454069	5.408143814	0.675670149	0	0.350165082	2	149009262	149020250	+	ENSGALG00000053652	protein_coding	--	GO:0005882|intermediate filament	GO:0005200|structural constituent of cytoskeleton	--	--	616	XP_025003984.1	XP_025003984.1 feather keratin 1-like isoform X2 [Gallus gallus]	sp|P02451|KRFT_LARNO	sp|P02451|KRFT_LARNO Feather keratin OS=Larus novaehollandiae PE=1 SV=1	9031.ENSGALP00000023460	annotation not avaliable	_	_	NOG231326	_
ENSGALG00000053659	1.218020857	0.394766779	1.601172273	8.18E-06	2.33E-05	up	yes	1.374324667	1.311854089	0.967883816	0.536457271	0.348686283	0.299156783	3	3292590	3299822	-	ENSGALG00000053659	protein_coding	"GO:0000122|negative regulation of transcription by RNA polymerase II; GO:0006351|transcription, DNA-templated; GO:0006355|regulation of transcription, DNA-templated; GO:0007165|signal transduction; GO:0007275|multicellular organism development; GO:0045892|negative regulation of transcription, DNA-templated"	GO:0000118|histone deacetylase complex; GO:0005654|nucleoplasm	"GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding; GO:0001227|DNA-binding transcription repressor activity, RNA polymerase II-specific; GO:0003700|DNA-binding transcription factor activity; GO:0044212|transcription regulatory region DNA binding; GO:0046872|metal ion binding"	--	--	2032	XP_025004398.1	XP_025004398.1 GDNF inducible zinc finger protein 1 isoform X1 [Gallus gallus]	sp|O75362|ZN217_HUMAN	sp|O75362|ZN217_HUMAN Zinc finger protein 217 OS=Homo sapiens GN=ZNF217 PE=1 SV=1	_	_	_	_	_	"PF00096.23|zf-C2H2|Zinc finger, C2H2 type|ENSGALT00000054581|m.10631:466-488;PF13894.3|zf-C2H2_4|C2H2-type zinc finger|ENSGALT00000054581|m.10631:466-488;PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000054581|m.10631:44-64;PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000054581|m.10631:267-285;PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000054581|m.10631:296-315;PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000054581|m.10631:354-376;PF12874.4|zf-met|Zinc-finger of C2H2 type|ENSGALT00000054581|m.10631:494-513;PF13912.3|zf-C2H2_6|C2H2-type zinc finger|ENSGALT00000054581|m.10631:266-290;PF13912.3|zf-C2H2_6|C2H2-type zinc finger|ENSGALT00000054581|m.10631:328-349"
ENSGALG00000053670	12.40993392	26.16411468	-1.075483243	3.08E-15	2.09E-14	down	yes	13.73161716	11.88262108	11.6155635	27.29707402	24.72278979	26.47248023	17	4947581	4951990	-	MEGF9	protein_coding	--	GO:0005604|basement membrane; GO:0016021|integral component of membrane	--	--	--	660	XP_019476965.1	XP_019476965.1 PREDICTED: multiple epidermal growth factor-like domains protein 9 [Meleagris gallopavo]	sp|Q8BH27|MEGF9_MOUSE	sp|Q8BH27|MEGF9_MOUSE Multiple epidermal growth factor-like domains protein 9 OS=Mus musculus GN=Megf9 PE=2 SV=1	9031.ENSGALP00000039196	multiple EGF-like-domains 9	_	KOG1836	_	PF00053.21|Laminin_EGF|Laminin EGF domain|ENSGALT00000105331|m.11905:21-67
ENSGALG00000053730	6.187514701	2.754796797	1.164516337	1.27E-07	4.50E-07	up	yes	7.218587251	5.494942255	5.849014597	3.458928046	2.273029358	2.532432987	16	1970006	1971151	+	ENSGALG00000053730	protein_coding	--	--	--	--	--	1146	PKU41653.1	PKU41653.1 rna-directed dna polymerase from mobile element jockey-like [Limosa lapponica baueri]	_	_	_	_	_	_	_	PF00078.24|RVT_1|Reverse transcriptase (RNA-dependent DNA polymerase)|ENSGALT00000104621|m.11360:48-275
ENSGALG00000053835	2.909105769	0.058002008	5.42380532	5.79E-22	6.09E-21	up	yes	3.267664441	2.620465756	2.839187109	0.057615284	0.040385917	0.076004824	KZ626838.1	70407	71438	-	ENSGALG00000053835	protein_coding	--	GO:0070062|extracellular exosome	--	--	--	1032	XP_025002217.1	XP_025002217.1 zonadhesin-like [Gallus gallus]	sp|Q9Y6R7|FCGBP_HUMAN	sp|Q9Y6R7|FCGBP_HUMAN IgGFc-binding protein OS=Homo sapiens GN=FCGBP PE=1 SV=3	9258.ENSOANP00000018670	annotation not avaliable	_	KOG1216	_	PF08742.8|C8|C8 domain|ENSGALT00000095899|m.9873:125-189;PF00094.22|VWD|von Willebrand factor type D domain|ENSGALT00000095899|m.9873:20-92
ENSGALG00000053860	0.073280216	0.199433315	-1.33044523	0.003699719	0.007089074	down	yes	0.052503576	0.104488241	0.062848832	0.166456912	0.269944643	0.16189839	2	15842529	15889404	-	ENSGALG00000053860	protein_coding	--	--	--	--	--	6324	XP_015137549.1	XP_015137549.1 uncharacterized protein LOC420486 [Gallus gallus]	_	_	9031.ENSGALP00000035178	hypothetical LOC420485	COG3321	KOG1202	_	"PF00109.23|ketoacyl-synt|Beta-ketoacyl synthase, N-terminal domain|ENSGALT00000103198|m.14919:9-256;PF08659.7|KR|KR domain|ENSGALT00000103198|m.14919:1736-1916;PF00698.18|Acyl_transf_1|Acyl transferase domain|ENSGALT00000103198|m.14919:531-832;PF02801.19|Ketoacyl-synt_C|Beta-ketoacyl synthase, C-terminal domain|ENSGALT00000103198|m.14919:265-382;PF14765.3|PS-DH|Polyketide synthase dehydratase|ENSGALT00000103198|m.14919:911-1164;PF16197.2|KAsynt_C_assoc|Ketoacyl-synthetase C-terminal extension|ENSGALT00000103198|m.14919:388-496;PF00550.22|PP-binding|Phosphopantetheine attachment site|ENSGALT00000103198|m.14919:2014-2078;PF00106.22|adh_short|short chain dehydrogenase|ENSGALT00000103198|m.14919:1737-1897"
ENSGALG00000053990	5.041253727	2.074460272	1.276967635	4.27E-07	1.42E-06	up	yes	3.948884754	5.877079096	5.297797331	2.239133588	2.097899311	1.886347916	12	18767970	18769200	+	ENSGALG00000053990	protein_coding	"GO:0000729|DNA double-strand break processing; GO:0000737|DNA catabolic process, endonucleolytic; GO:0006303|double-strand break repair via nonhomologous end joining; GO:0008283|cell population proliferation; GO:0010452|histone H3-K36 methylation; GO:0015074|DNA integration; GO:0031297|replication fork processing; GO:0044774|mitotic DNA integrity checkpoint; GO:0051568|histone H3-K4 methylation; GO:0071157|negative regulation of cell cycle arrest; GO:0090305|nucleic acid phosphodiester bond hydrolysis; GO:0097676|histone H3-K36 dimethylation; GO:2000373|positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity; GO:2001034|positive regulation of double-strand break repair via nonhomologous end joining; GO:2001251|negative regulation of chromosome organization"	GO:0005634|nucleus; GO:0005730|nucleolus; GO:0035861|site of double-strand break	GO:0000014|single-stranded DNA endodeoxyribonuclease activity; GO:0003677|DNA binding; GO:0003690|double-stranded DNA binding; GO:0003697|single-stranded DNA binding; GO:0004519|endonuclease activity; GO:0008270|zinc ion binding; GO:0042800|histone methyltransferase activity (H3-K4 specific); GO:0042803|protein homodimerization activity; GO:0044547|DNA topoisomerase binding; GO:0046975|histone methyltransferase activity (H3-K36 specific)	ko:K11433|SETMAR	ko00310|Lysine degradation	894	XP_015148665.1	XP_015148665.1 histone-lysine N-methyltransferase SETMAR [Gallus gallus]	sp|Q53H47|SETMR_HUMAN	sp|Q53H47|SETMR_HUMAN Histone-lysine N-methyltransferase SETMAR OS=Homo sapiens GN=SETMAR PE=1 SV=2	_	_	_	_	_	PF00856.25|SET|SET domain|ENSGALT00000091097|m.8075:129-241
ENSGALG00000053991	11.32218129	5.591633786	1.016506013	0.005070716	0.009493254	up	yes	13.46550055	11.80457431	8.696469008	5.505460473	4.515145517	6.754295368	10	20570775	20571216	-	ENSGALG00000053991	protein_coding	--	--	--	--	--	180	XP_015147667.1	XP_015147667.1 small EDRK-rich factor 2 [Gallus gallus]	sp|A5JSS4|SERF2_CAPHI	sp|A5JSS4|SERF2_CAPHI Small EDRK-rich factor 2 OS=Capra hircus GN=SERF2 PE=3 SV=1	9615.ENSCAFP00000007310	similar to Small EDRK-rich factor 2 (4F5rel)	_	KOG4488	_	_
ENSGALG00000054010	68.26473683	7.736502486	3.139734856	2.15E-88	2.04E-86	up	yes	76.81899523	66.07960056	61.8956147	7.407346818	8.209355485	7.592805155	2	148921130	148921426	-	ENSGALG00000054010	protein_coding	--	GO:0005882|intermediate filament	GO:0005200|structural constituent of cytoskeleton	--	--	297	XP_003643694.1	XP_003643694.1 feather keratin 1-like [Gallus gallus]	sp|P02451|KRFT_LARNO	sp|P02451|KRFT_LARNO Feather keratin OS=Larus novaehollandiae PE=1 SV=1	9031.ENSGALP00000034768	annotation not avaliable	_	_	NOG231326	_
ENSGALG00000054015	7.371987576	3.409645329	1.110162607	3.09E-06	9.28E-06	up	yes	5.060368701	7.466911788	9.588682238	3.450000441	3.57742622	3.201509325	19	7343996	7346361	+	PRR11	protein_coding	GO:0007050|cell cycle arrest; GO:0051726|regulation of cell cycle	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0016020|membrane	--	--	--	833	XP_001235261.4	XP_001235261.4 proline-rich protein 11 isoform X5 [Gallus gallus]	sp|Q96HE9|PRR11_HUMAN	sp|Q96HE9|PRR11_HUMAN Proline-rich protein 11 OS=Homo sapiens GN=PRR11 PE=1 SV=1	9031.ENSGALP00000034156	proline rich 11	_	_	NOG41738	_
ENSGALG00000054017	3.108926799	1.427108077	1.11788113	2.07E-05	5.61E-05	up	yes	3.697620288	2.277322662	3.351837448	1.265676387	1.433147403	1.582500443	12	20327306	20328730	+	ENSGALG00000054017	protein_coding	GO:0016180|snRNA processing; GO:0042795|snRNA transcription by RNA polymerase II	GO:0005634|nucleus; GO:0005654|nucleoplasm; GO:0005737|cytoplasm; GO:0016020|membrane; GO:0016021|integral component of membrane; GO:0031965|nuclear membrane; GO:0032039|integrator complex	--	ko:K13142|INTS5	--	1425	XP_015130377.2	"XP_015130377.2 LOW QUALITY PROTEIN: integrator complex subunit 5, partial [Gallus gallus]"	sp|Q6P9B9|INT5_HUMAN	sp|Q6P9B9|INT5_HUMAN Integrator complex subunit 5 OS=Homo sapiens GN=INTS5 PE=1 SV=1	_	_	_	_	_	PF14838.3|INTS5_C|Integrator complex subunit 5 C-terminus|ENSGALT00000105688|m.8172:169-465;PF14838.3|INTS5_C|Integrator complex subunit 5 C-terminus|ENSGALT00000105688|m.8173:67-169
ENSGALG00000054034	8.229010992	4.033066506	1.027021232	3.30E-31	5.56E-30	up	yes	8.282726244	8.341173861	8.063132871	3.934163152	3.834201321	4.330835046	5	17291805	17302263	+	TNKS1BP1	protein_coding	GO:0006302|double-strand break repair; GO:0010800|positive regulation of peptidyl-threonine phosphorylation; GO:0031954|positive regulation of protein autophosphorylation; GO:0033138|positive regulation of peptidyl-serine phosphorylation; GO:0071479|cellular response to ionizing radiation	GO:0005634|nucleus; GO:0005720|nuclear heterochromatin; GO:0005737|cytoplasm; GO:0005856|cytoskeleton; GO:0005913|cell-cell adherens junction; GO:0030014|CCR4-NOT complex	GO:0019899|enzyme binding; GO:0044877|protein-containing complex binding; GO:0045296|cadherin binding; GO:0071532|ankyrin repeat binding	--	--	5859	XP_421067.4	XP_421067.4 182 kDa tankyrase-1-binding protein isoform X3 [Gallus gallus]	sp|P58871|TB182_MOUSE	sp|P58871|TB182_MOUSE 182 kDa tankyrase-1-binding protein OS=Mus musculus GN=Tnks1bp1 PE=1 SV=2	_	_	_	_	_	PF15327.3|Tankyrase_bdg_C|Tankyrase binding protein C terminal domain|ENSGALT00000093213|m.2803:1498-1666
ENSGALG00000054083	81.92556366	26.36948047	1.635073629	3.18E-48	1.09E-46	up	yes	80.38768722	87.17224108	78.21676268	29.01801166	24.90009244	25.19033732	1	48153238	48153627	-	H2A-VII	protein_coding	GO:0006342|chromatin silencing	GO:0000786|nucleosome; GO:0000790|nuclear chromatin	GO:0003677|DNA binding; GO:0046982|protein heterodimerization activity	ko:K11251|H2A	ko05034|Alcoholism; ko05322|Systemic lupus erythematosus	390	EOB06730.1	"EOB06730.1 Histone H2A-IV, partial [Anas platyrhynchos]"	sp|P02263|H2A4_CHICK	sp|P02263|H2A4_CHICK Histone H2A-IV OS=Gallus gallus PE=1 SV=2	9031.ENSGALP00000019162	Histone H2A-IV 	COG5262	KOG1756	_	PF16211.2|Histone_H2A_C|C-terminus of histone H2A|ENSGALT00000108326|m.1205:92-125;PF00125.21|Histone|Core histone H2A/H2B/H3/H4|ENSGALT00000108326|m.1205:5-89;PF00808.20|CBFD_NFYB_HMF|Histone-like transcription factor (CBF/NF-Y) and archaeal histone|ENSGALT00000108326|m.1205:25-88
ENSGALG00000054145	0.091870028	0.656719907	-2.710351162	5.30E-07	1.74E-06	down	yes	0.090729383	0.133045725	0.051834975	0.648426167	0.654867292	0.666866261	10	12097214	12107184	+	ENSGALG00000054145	protein_coding	--	--	--	--	--	2323	XP_413844.3	XP_413844.3 ADAMTS-like protein 3 isoform X1 [Gallus gallus]	_	_	_	_	_	_	_	PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000091228|m.5597:95-147;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000091228|m.5597:155-182;PF00090.16|TSP_1|Thrombospondin type 1 domain|ENSGALT00000091228|m.5597:273-320;PF08686.8|PLAC|PLAC (protease and lacunin) domain|ENSGALT00000091228|m.5597:330-360
ENSGALG00000054162	0.382964174	1.423264482	-1.866835163	8.21E-07	2.65E-06	down	yes	0.423221599	0.288141698	0.437529223	1.193955283	1.410796163	1.665041998	16	1077028	1078980	+	ENSGALG00000054162	protein_coding	GO:0006953|acute-phase response	GO:0005576|extracellular region; GO:0005886|plasma membrane; GO:0009897|external side of plasma membrane; GO:0016021|integral component of membrane	GO:0005044|scavenger receptor activity	--	--	1743	XP_025011582.1	XP_025011582.1 scavenger receptor cysteine-rich type 1 protein M130-like isoform X2 [Gallus gallus]	sp|Q2VLH6|C163A_MOUSE	sp|Q2VLH6|C163A_MOUSE Scavenger receptor cysteine-rich type 1 protein M130 OS=Mus musculus GN=Cd163 PE=1 SV=2	9031.ENSGALP00000002137	annotation not avaliable	_	_	NOG83796	PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000099800|m.11252:55-151;PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000099800|m.11252:160-257;PF00530.15|SRCR|Scavenger receptor cysteine-rich domain|ENSGALT00000099800|m.11253:69-163
ENSGALG00000054173	8.3883287	3.980402647	1.073567927	5.70E-18	4.68E-17	up	yes	8.924020072	8.659984325	7.580981701	4.031395714	3.823535431	4.086276794	4	75879121	75894354	+	ENSGALG00000054173	protein_coding	--	--	--	--	--	2409	POI33702.1	POI33702.1 hypothetical protein CIB84_002546 [Bambusicola thoracicus]	sp|A8MVM7|YD021_HUMAN	sp|A8MVM7|YD021_HUMAN Putative uncharacterized protein ENSP00000382790 OS=Homo sapiens PE=5 SV=3	9031.ENSGALP00000036519	similar to chromosome 10 open reading frame 12	_	_	NOG122934	PF15090.3|DUF4553|Domain of unknown function (DUF4553)|ENSGALT00000065542|m.1308:31-349
ENSGALG00000054187	0.743057077	0.264655694	1.455135014	1.91E-07	6.61E-07	up	yes	0.727243844	0.774829235	0.727098154	0.217986315	0.301104577	0.274876192	2	131174886	131186117	+	ENSGALG00000054187	protein_coding	GO:0007158|neuron cell-cell adhesion; GO:0007165|signal transduction; GO:0007268|chemical synaptic transmission; GO:0007269|neurotransmitter secretion; GO:0007416|synapse assembly; GO:0030534|adult behavior; GO:0035176|social behavior; GO:0042297|vocal learning; GO:0071625|vocalization behavior; GO:0097104|postsynaptic membrane assembly; GO:0097116|gephyrin clustering involved in postsynaptic density assembly; GO:0097118|neuroligin clustering involved in postsynaptic membrane assembly; GO:0097119|postsynaptic density protein 95 clustering	GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0032991|protein-containing complex; GO:0098793|presynapse	GO:0004888|transmembrane signaling receptor activity; GO:0005246|calcium channel regulator activity; GO:0046872|metal ion binding; GO:0050839|cell adhesion molecule binding; GO:0097109|neuroligin family protein binding	--	--	4637	XP_025003522.1	"XP_025003522.1 nascent polypeptide-associated complex subunit alpha, muscle-specific form-like [Gallus gallus]"	sp|Q9P2S2|NRX2A_HUMAN	sp|Q9P2S2|NRX2A_HUMAN Neurexin-2 OS=Homo sapiens GN=NRXN2 PE=2 SV=1	9823.ENSSSCP00000013851	neurexin 2	_	KOG3514	_	PF02210.21|Laminin_G_2|Laminin G domain|ENSGALT00000101514|m.2371:1210-1338;PF00054.20|Laminin_G_1|Laminin G domain|ENSGALT00000101514|m.2371:1210-1340
ENSGALG00000054223	22.45690157	46.01257323	-1.034540476	2.45E-40	6.29E-39	down	yes	21.41656412	22.04287628	23.91126431	45.35318828	48.01664598	44.66788544	2	98750108	98758304	-	ENSGALG00000054223	protein_coding	GO:0001578|microtubule bundle formation; GO:0010506|regulation of autophagy; GO:0045197|establishment or maintenance of epithelial cell apical/basal polarity; GO:0090314|positive regulation of protein targeting to membrane; GO:2000576|positive regulation of microtubule motor activity	GO:0000922|spindle pole; GO:0005615|extracellular space; GO:0005737|cytoplasm; GO:0005856|cytoskeleton; GO:0016324|apical plasma membrane; GO:0016327|apicolateral plasma membrane; GO:0016328|lateral plasma membrane; GO:0030496|midbody; GO:0097427|microtubule bundle	GO:0003723|RNA binding; GO:0008017|microtubule binding; GO:0042803|protein homodimerization activity	--	--	1770	XP_021242137.1	XP_021242137.1 microtubule cross-linking factor 1 isoform X2 [Numida meleagris]	sp|Q3UHU5|MTCL1_MOUSE	sp|Q3UHU5|MTCL1_MOUSE Microtubule cross-linking factor 1 OS=Mus musculus GN=Mtcl1 PE=1 SV=1	_	_	_	_	_	_
ENSGALG00000054306	13.19801015	5.614707175	1.231563238	6.44E-16	4.61E-15	up	yes	13.7792535	12.84214363	12.97263333	6.460551406	5.526399953	4.857170168	20	9922494	9923968	+	SRXN1	protein_coding	GO:0006979|response to oxidative stress; GO:0034599|cellular response to oxidative stress	GO:0005829|cytosol	"GO:0005524|ATP binding; GO:0016667|oxidoreductase activity, acting on a sulfur group of donors; GO:0032542|sulfiredoxin activity"	ko:K12260|SRX1	--	1086	XP_015151960.1	XP_015151960.1 sulfiredoxin-1 [Gallus gallus]	sp|Q9BYN0|SRXN1_HUMAN	sp|Q9BYN0|SRXN1_HUMAN Sulfiredoxin-1 OS=Homo sapiens GN=SRXN1 PE=1 SV=2	_	_	_	_	_	PF02195.15|ParBc|ParB-like nuclease domain|ENSGALT00000097120|m.3358:64-149
ENSGALG00000054317	0.137221896	0.486220922	-1.75299031	0.008255876	0.014824752	down	yes	0	0.25111549	0.160550197	0.475671785	0.375104397	0.607886583	1	84390198	84399002	+	ENSGALG00000054317	protein_coding	GO:0060285|cilium-dependent cell motility	GO:0031514|motile cilium	--	--	--	2000	XP_004938274.1	XP_004938274.1 cilia- and flagella-associated protein 44 isoform X2 [Gallus gallus]	sp|A8J1V4|CFA44_CHLRE	sp|A8J1V4|CFA44_CHLRE Cilia- and flagella-associated protein 44 OS=Chlamydomonas reinhardtii GN=CFAP44 PE=1 SV=1	_	_	_	_	_	_
ENSGALG00000054397	3.101022611	1.504350596	1.03868963	0.00463366	0.008732749	up	yes	3.482193715	2.889087911	2.931786208	1.447696737	1.667130652	1.398224399	16	2019868	2064486	-	ENSGALG00000054397	protein_coding	GO:0002474|antigen processing and presentation of peptide antigen via MHC class I	GO:0016021|integral component of membrane; GO:0042612|MHC class I protein complex	--	--	--	575	XP_025011666.1	"XP_025011666.1 class I histocompatibility antigen, F10 alpha chain-like isoform X2 [Gallus gallus]"	sp|P15979|HA1F_CHICK	"sp|P15979|HA1F_CHICK Class I histocompatibility antigen, F10 alpha chain OS=Gallus gallus PE=2 SV=1"	9031.ENSGALP00000040364	similar to class I alpha chain	_	_	NOG42056	_
ENSGALG00000054542	1.278016533	0.25079561	2.304159622	1.25E-06	3.95E-06	up	yes	1.236770471	1.317428134	1.279850995	0.315991	0.036916091	0.39947974	22	6587	9347	-	ENSGALG00000054542	protein_coding	GO:0006556|S-adenosylmethionine biosynthetic process; GO:0006730|one-carbon metabolic process; GO:0032259|methylation; GO:0034214|protein hexamerization; GO:0051291|protein heterooligomerization; GO:1990830|cellular response to leukemia inhibitory factor	GO:0005829|cytosol; GO:0048269|methionine adenosyltransferase complex	GO:0004478|methionine adenosyltransferase activity; GO:0005524|ATP binding; GO:0042802|identical protein binding; GO:0046872|metal ion binding	ko:K00789|metK	ko00270|Cysteine and methionine metabolism; ko01100|Metabolic pathways; ko01110|Biosynthesis of secondary metabolites; ko01230|Biosynthesis of amino acids	2258	XP_001364097.1	XP_001364097.1 PREDICTED: S-adenosylmethionine synthase [Monodelphis domestica]	sp|P31153|METK2_HUMAN	sp|P31153|METK2_HUMAN S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens GN=MAT2A PE=1 SV=1	_	_	_	_	_	"PF02773.13|S-AdoMet_synt_C|S-adenosylmethionine synthetase, C-terminal domain|ENSGALT00000106066|m.4428:354-388"
ENSGALG00000054550	0.696730336	0.289588938	1.238175482	0.015295658	0.026026959	up	yes	0.711604641	0.664044361	0.714542007	0.474503776	0.15351111	0.240751929	1	171874307	171875935	-	ENSGALG00000054550	protein_coding	--	--	--	--	--	1629	PKU41653.1	PKU41653.1 rna-directed dna polymerase from mobile element jockey-like [Limosa lapponica baueri]	_	_	_	_	_	_	_	PF00078.24|RVT_1|Reverse transcriptase (RNA-dependent DNA polymerase)|ENSGALT00000107588|m.4364:208-426
ENSGALG00000054619	24.48146329	71.60258392	-1.54793415	1.93E-103	2.60E-101	down	yes	24.3836423	23.0528578	26.00788976	72.56984919	73.34004405	68.8978585	1	193942684	194025658	+	GAB2	protein_coding	GO:0007411|axon guidance; GO:0008284|positive regulation of cell population proliferation; GO:0030316|osteoclast differentiation; GO:0038095|Fc-epsilon receptor signaling pathway; GO:0043306|positive regulation of mast cell degranulation; GO:0048015|phosphatidylinositol-mediated signaling	GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005886|plasma membrane	"GO:0005068|transmembrane receptor protein tyrosine kinase adaptor activity; GO:0005547|phosphatidylinositol-3,4,5-trisphosphate binding; GO:0043325|phosphatidylinositol-3,4-bisphosphate binding"	ko:K08091|GAB2	ko04014|Ras signaling pathway; ko04071|Sphingolipid signaling pathway; ko04072|Phospholipase D signaling pathway; ko04380|Osteoclast differentiation; ko04664|Fc epsilon RI signaling pathway; ko04666|Fc gamma R-mediated phagocytosis; ko05220|Chronic myeloid leukemia	2068	XP_004938986.3	XP_004938986.3 GRB2-associated-binding protein 2 [Gallus gallus]	sp|Q9UQC2|GAB2_HUMAN	sp|Q9UQC2|GAB2_HUMAN GRB2-associated-binding protein 2 OS=Homo sapiens GN=GAB2 PE=1 SV=1	_	_	_	_	_	PF00169.26|PH|PH domain|ENSGALT00000102699|m.4787:7-116
ENSGALG00000054643	22.20641182	0.816739791	4.74804869	3.73E-46	1.19E-44	up	yes	25.01496149	21.33278443	20.27148953	0.667328542	1.122646904	0.660243926	2	148977797	148978093	+	ENSGALG00000054643	protein_coding	--	GO:0005882|intermediate filament	GO:0005200|structural constituent of cytoskeleton	--	--	297	XP_015138683.1	XP_015138683.1 feather keratin 1-like [Gallus gallus]	sp|P02450|KRFC_CHICK	sp|P02450|KRFC_CHICK Feather keratin 1 OS=Gallus gallus PE=3 SV=2	9031.ENSGALP00000018710	similar to feather beta keratin	_	_	NOG231326	_
ENSGALG00000054655	0.076479509	0.376570895	-2.160302777	0.006278779	0.01152811	down	yes	0.135769965	0.009049696	0.084618867	0.373736811	0.356349665	0.399626208	Z	765431	807123	-	ENSGALG00000054655	protein_coding	--	GO:0005737|cytoplasm	GO:0004674|protein serine/threonine kinase activity; GO:0005524|ATP binding	ko:K08868|ALPK	--	8538	XP_424461.2	XP_424461.2 alpha-protein kinase 2 [Gallus gallus]	sp|Q86TB3|ALPK2_HUMAN	sp|Q86TB3|ALPK2_HUMAN Alpha-protein kinase 2 OS=Homo sapiens GN=ALPK2 PE=2 SV=3	_	_	_	_	_	PF02816.15|Alpha_kinase|Alpha-kinase family|ENSGALT00000099826|m.10226:1556-1755
ENSGALG00000054759	4.636358997	2.187095535	1.080503024	2.62E-13	1.54E-12	up	yes	4.862370679	4.568200815	4.478505497	2.38531319	1.974233667	2.201739746	9	22252414	22257167	-	B3GALNT1	protein_coding	GO:0006486|protein glycosylation; GO:0006687|glycosphingolipid metabolic process; GO:0009312|oligosaccharide biosynthetic process	GO:0000139|Golgi membrane; GO:0016021|integral component of membrane	"GO:0008499|UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity; GO:0047273|galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity"	"ko:K00719|B3GALNT1,B3GALT3"	ko00601|Glycosphingolipid biosynthesis - lacto and neolacto series; ko00603|Glycosphingolipid biosynthesis - globo and isoglobo series; ko01100|Metabolic pathways	2850	XP_004943571.1	"XP_004943571.1 UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 isoform X1 [Gallus gallus]"	sp|O75752|B3GL1_HUMAN	"sp|O75752|B3GL1_HUMAN UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 OS=Homo sapiens GN=B3GALNT1 PE=1 SV=1"	9031.ENSGALP00000015509	"beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)"	_	KOG2287	_	PF01762.18|Galactosyl_T|Galactosyltransferase|ENSGALT00000098207|m.9303:81-269;PF02434.13|Fringe|Fringe-like|ENSGALT00000098207|m.9303:150-269
ENSGALG00000054766	2.472122791	0.515542039	2.23969641	1.74E-33	3.28E-32	up	yes	2.658443696	2.434220942	2.323703736	0.571410731	0.532970157	0.442245229	27	3941850	3960190	+	ITGA2B	protein_coding	GO:0002576|platelet degranulation; GO:0002687|positive regulation of leukocyte migration; GO:0007155|cell adhesion; GO:0007160|cell-matrix adhesion; GO:0007229|integrin-mediated signaling pathway; GO:0030198|extracellular matrix organization; GO:0045652|regulation of megakaryocyte differentiation; GO:0070527|platelet aggregation	GO:0005886|plasma membrane; GO:0005887|integral component of plasma membrane; GO:0005925|focal adhesion; GO:0008305|integrin complex; GO:0009897|external side of plasma membrane; GO:0009986|cell surface; GO:0031092|platelet alpha granule membrane; GO:0070062|extracellular exosome; GO:0072562|blood microparticle	GO:0042802|identical protein binding; GO:0046872|metal ion binding; GO:0050840|extracellular matrix binding; GO:0070051|fibrinogen binding	--	--	3380	XP_024999916.1	XP_024999916.1 integrin alpha-IIb isoform X2 [Gallus gallus]	sp|P08514|ITA2B_HUMAN	sp|P08514|ITA2B_HUMAN Integrin alpha-IIb OS=Homo sapiens GN=ITGA2B PE=1 SV=3	_	_	_	_	_	"PF08441.9|Integrin_alpha2|Integrin alpha|ENSGALT00000102542|m.8714:317-718;PF01839.20|FG-GAP|FG-GAP repeat|ENSGALT00000102542|m.8714:157-188;PF13517.3|VCBS|Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella|ENSGALT00000102542|m.8714:165-243"
ENSGALG00000054783	17.48378462	55.96827801	-1.678024671	4.29E-124	1.10E-121	down	yes	18.13743144	17.04363867	17.27028376	56.36802544	52.9432561	58.5935525	2	141967432	142007621	-	NDRG1	protein_coding	GO:0032287|peripheral nervous system myelin maintenance; GO:0042127|regulation of cell population proliferation; GO:0045576|mast cell activation	GO:0005634|nucleus; GO:0005815|microtubule organizing center; GO:0005829|cytosol; GO:0005874|microtubule; GO:0005886|plasma membrane	--	ko:K18266|NDRG1	--	2847	XP_418430.2	XP_418430.2 protein NDRG1 [Gallus gallus]	sp|Q4R4Q3|NDRG1_MACFA	sp|Q4R4Q3|NDRG1_MACFA Protein NDRG1 OS=Macaca fascicularis GN=Ndrg1 PE=2 SV=1	9031.ENSGALP00000026092	N-myc downstream regulated gene 1	_	KOG2931	_	PF03096.11|Ndr|Ndr family|ENSGALT00000096810|m.2574:57-339
ENSGALG00000054836	1.10729193	0.271624938	1.98815919	0.000173411	0.000410527	up	yes	0.605644702	1.332177665	1.384053423	0.403052279	0.221104861	0.190717675	1	88852020	88853150	+	ENSGALG00000054836	protein_coding	--	GO:0016020|membrane; GO:0016021|integral component of membrane	--	--	--	1131	XP_025000011.1	"XP_025000011.1 inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 [Gallus gallus]"	sp|Q66H52|IPIL1_RAT	"sp|Q66H52|IPIL1_RAT Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 OS=Rattus norvegicus GN=Itpripl1 PE=2 SV=1"	9031.ENSGALP00000031820	"inositol 1,4,5-triphosphate receptor interacting protein-like 1"	_	_	NOG267113	_
ENSGALG00000054937	0.374235357	1.122087935	-1.558923839	3.87E-05	0.00010103	down	yes	0.443472383	0.228812311	0.450421376	1.260352298	0.571647044	1.534264463	13	5478546	5485038	+	ENSGALG00000054937	protein_coding	GO:0001843|neural tube closure; GO:0003007|heart morphogenesis; GO:0006915|apoptotic process; GO:0006919|activation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0007165|signal transduction; GO:0008285|negative regulation of cell population proliferation; GO:0008360|regulation of cell shape; GO:0021575|hindbrain morphogenesis; GO:0030036|actin cytoskeleton organization; GO:0030336|negative regulation of cell migration; GO:0030900|forebrain development; GO:0032956|regulation of actin cytoskeleton organization; GO:0035024|negative regulation of Rho protein signal transduction; GO:0035307|positive regulation of protein dephosphorylation; GO:0048041|focal adhesion assembly; GO:0051056|regulation of small GTPase mediated signal transduction; GO:0051497|negative regulation of stress fiber assembly; GO:0051895|negative regulation of focal adhesion assembly; GO:1900119|positive regulation of execution phase of apoptosis	GO:0005634|nucleus; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005901|caveola; GO:0005925|focal adhesion; GO:0030864|cortical actin cytoskeleton; GO:0032587|ruffle membrane	GO:0005096|GTPase activator activity; GO:0008289|lipid binding; GO:0042169|SH2 domain binding	ko:K20632|DLC	--	3190	XP_004944854.1	XP_004944854.1 rho GTPase-activating protein 7-like isoform X1 [Gallus gallus]	sp|Q96QB1|RHG07_HUMAN	sp|Q96QB1|RHG07_HUMAN Rho GTPase-activating protein 7 OS=Homo sapiens GN=DLC1 PE=1 SV=4	9031.ENSGALP00000002905	similar to MGC83845 protein	_	KOG2200	_	PF00620.24|RhoGAP|RhoGAP domain|ENSGALT00000097729|m.8468:540-684
ENSGALG00000054942	0.541327774	0.187365257	1.482042233	0.001514654	0.003100384	up	yes	0.411310885	0.619019285	0.593653153	0.105856841	0.222603723	0.233635207	Z	81765424	81795194	+	ENSGALG00000054942	protein_coding	GO:0007165|signal transduction; GO:0008277|regulation of G protein-coupled receptor signaling pathway; GO:0090150|establishment of protein localization to membrane	GO:0005829|cytosol; GO:0005856|cytoskeleton; GO:0005886|plasma membrane; GO:0005938|cell cortex; GO:0032991|protein-containing complex; GO:0070062|extracellular exosome	--	--	--	1883	XP_003643153.2	XP_003643153.2 FERM and PDZ domain-containing protein 1 isoform X1 [Gallus gallus]	sp|A2AKB4|FRPD1_MOUSE	sp|A2AKB4|FRPD1_MOUSE FERM and PDZ domain-containing protein 1 OS=Mus musculus GN=Frmpd1 PE=1 SV=1	9258.ENSOANP00000001384	similar to FERM and PDZ domain containing 1	_	KOG3552	_	PF00595.21|PDZ|PDZ domain (Also known as DHR or GLGF)|ENSGALT00000106270|m.12100:76-132
ENSGALG00000054991	53.42207184	15.70099621	1.765931296	5.10E-126	1.34E-123	up	yes	52.82434932	55.20417564	52.23769058	14.89732491	16.46470713	15.7409566	22	5310476	5313689	+	ENSGALG00000054991	protein_coding	GO:0006895|Golgi to endosome transport; GO:0043687|post-translational protein modification; GO:0044267|cellular protein metabolic process; GO:0061024|membrane organization	GO:0005654|nucleoplasm; GO:0005768|endosome; GO:0005788|endoplasmic reticulum lumen; GO:0005794|Golgi apparatus; GO:0005802|trans-Golgi network; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0016021|integral component of membrane; GO:0030133|transport vesicle; GO:0030140|trans-Golgi network transport vesicle; GO:0030665|clathrin-coated vesicle membrane	--	--	--	1977	XP_015128437.1	XP_015128437.1 trans-Golgi network integral membrane protein 2 [Gallus gallus]	sp|O43493|TGON2_HUMAN	sp|O43493|TGON2_HUMAN Trans-Golgi network integral membrane protein 2 OS=Homo sapiens GN=TGOLN2 PE=1 SV=2	_	_	_	_	_	_
ENSGALG00000055014	78.70303355	26.7034554	1.55903594	1.18E-39	2.88E-38	up	yes	74.99826551	78.39427984	82.71655531	30.7662813	23.62782494	25.71625997	1	48137890	48138991	-	ENSGALG00000055014	protein_coding	GO:0006334|nucleosome assembly; GO:0006335|DNA replication-dependent nucleosome assembly; GO:0051290|protein heterotetramerization; GO:0060968|regulation of gene silencing	"GO:0000784|nuclear chromosome, telomeric region; GO:0000786|nucleosome; GO:0000788|nuclear nucleosome; GO:0005634|nucleus; GO:0016020|membrane; GO:0032991|protein-containing complex; GO:0070062|extracellular exosome"	GO:0031492|nucleosomal DNA binding; GO:0042393|histone binding; GO:0045296|cadherin binding; GO:0046982|protein heterodimerization activity	--	--	411	XP_006988932.1	XP_006988932.1 PREDICTED: histone H3.1-like [Peromyscus maniculatus bairdii]	sp|P68432|H31_BOVIN	sp|P68432|H31_BOVIN Histone H3.1 OS=Bos taurus PE=1 SV=2	_	_	_	_	_	PF00125.21|Histone|Core histone H2A/H2B/H3/H4|ENSGALT00000058129|m.1198:1-91
ENSGALG00000055023	0.81744741	2.293145634	-1.476866113	7.65E-08	2.76E-07	down	yes	0.75114013	0.938291978	0.762910123	2.668433323	2.057506811	2.153496769	33	5563234	5566047	-	INHBE	protein_coding	GO:0010862|positive regulation of pathway-restricted SMAD protein phosphorylation; GO:0042981|regulation of apoptotic process; GO:0043408|regulation of MAPK cascade; GO:0048468|cell development; GO:0060395|SMAD protein signal transduction	GO:0005615|extracellular space	GO:0005125|cytokine activity; GO:0005160|transforming growth factor beta receptor binding; GO:0005179|hormone activity; GO:0008083|growth factor activity	ko:K04667|INHB	ko04350|TGF-beta signaling pathway; ko04550|Signaling pathways regulating pluripotency of stem cells	1894	XP_015128061.1	XP_015128061.1 inhibin beta E chain [Gallus gallus]	sp|P58166|INHBE_HUMAN	sp|P58166|INHBE_HUMAN Inhibin beta E chain OS=Homo sapiens GN=INHBE PE=1 SV=1	_	_	_	_	_	PF00019.17|TGF_beta|Transforming growth factor beta like domain|ENSGALT00000103537|m.15172:270-372;PF00688.15|TGFb_propeptide|TGF-beta propeptide|ENSGALT00000103537|m.15172:60-221
ENSGALG00000055035	1.631690771	0.69528605	1.218901998	0.007079267	0.012874592	up	yes	2.107643564	1.962981792	0.824446958	0.771359651	0.720921363	0.593577134	4	18701837	18702761	+	ENSGALG00000055035	protein_coding	GO:0001701|in utero embryonic development; GO:0006816|calcium ion transport; GO:0007165|signal transduction; GO:0007173|epidermal growth factor receptor signaling pathway; GO:0007202|activation of phospholipase C activity; GO:0009306|protein secretion; GO:0009395|phospholipid catabolic process; GO:0009629|response to gravity; GO:0010243|response to organonitrogen compound; GO:0010634|positive regulation of epithelial cell migration; GO:0016477|cell migration; GO:0019722|calcium-mediated signaling; GO:0032959|inositol trisphosphate biosynthetic process; GO:0038096|Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0042542|response to hydrogen peroxide; GO:0043278|response to morphine; GO:0043536|positive regulation of blood vessel endothelial cell migration; GO:0045766|positive regulation of angiogenesis; GO:0050852|T cell receptor signaling pathway; GO:0051281|positive regulation of release of sequestered calcium ion into cytosol; GO:0071364|cellular response to epidermal growth factor stimulus; GO:1901339|regulation of store-operated calcium channel activity	GO:0001726|ruffle; GO:0005737|cytoplasm; GO:0005829|cytosol; GO:0005886|plasma membrane; GO:0005911|cell-cell junction; GO:0008180|COP9 signalosome; GO:0030027|lamellipodium; GO:0042995|cell projection	GO:0004435|phosphatidylinositol phospholipase C activity; GO:0005158|insulin receptor binding; GO:0005168|neurotrophin TRKA receptor binding; GO:0005509|calcium ion binding; GO:0019901|protein kinase binding; GO:0030971|receptor tyrosine kinase binding; GO:0035254|glutamate receptor binding; GO:0051219|phosphoprotein binding	ko:K01116|PLCG1	ko00562|Inositol phosphate metabolism; ko01100|Metabolic pathways; ko01521|EGFR tyrosine kinase inhibitor resistance; ko04012|ErbB signaling pathway; ko04014|Ras signaling pathway; ko04015|Rap1 signaling pathway; ko04020|Calcium signaling pathway; ko04064|NF-kappa B signaling pathway; ko04066|HIF-1 signaling pathway; ko04070|Phosphatidylinositol signaling system; ko04072|Phospholipase D signaling pathway; ko04360|Axon guidance; ko04370|VEGF signaling pathway; ko04650|Natural killer cell mediated cytotoxicity; ko04658|Th1 and Th2 cell differentiation; ko04659|Th17 cell differentiation; ko04660|T cell receptor signaling pathway; ko04664|Fc epsilon RI signaling pathway; ko04666|Fc gamma R-mediated phagocytosis; ko04670|Leukocyte transendothelial migration; ko04722|Neurotrophin signaling pathway; ko04750|Inflammatory mediator regulation of TRP channels; ko04919|Thyroid hormone signaling pathway; ko04933|AGE-RAGE signaling pathway in diabetic complications; ko05110|Vibrio cholerae infection; ko05120|Epithelial cell signaling in Helicobacter pylori infection; ko05169|Epstein-Barr virus infection; ko05200|Pathways in cancer; ko05205|Proteoglycans in cancer; ko05206|MicroRNAs in cancer; ko05214|Glioma; ko05223|Non-small cell lung cancer; ko05231|Choline metabolism in cancer	925	RLV98789.1	RLV98789.1 hypothetical protein DV515_00010359 [Erythrura gouldiae]	sp|P10686|PLCG1_RAT	"sp|P10686|PLCG1_RAT 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 OS=Rattus norvegicus GN=Plcg1 PE=1 SV=1"	_	_	_	_	_	PF00017.21|SH2|SH2 domain|ENSGALT00000090897|m.16699:3-64
ENSGALG00000055058	3.586411019	9.15691757	-1.349878791	2.85E-29	4.28E-28	down	yes	4.129395698	3.257779927	3.372057431	8.872248025	9.642181986	8.956322698	1	6730670	6745495	+	ENSGALG00000055058	protein_coding	--	--	--	--	--	3190	XP_015152812.2	XP_015152812.2 LOW QUALITY PROTEIN: proline and serine-rich protein 2 [Gallus gallus]	sp|Q8C5R2|PRSR2_MOUSE	sp|Q8C5R2|PRSR2_MOUSE Proline and serine-rich protein 2 OS=Mus musculus GN=Proser2 PE=1 SV=3	9031.ENSGALP00000010817	chromosome 10 open reading frame 47	_	_	NOG47684	_
ENSGALG00000055117	0.265735712	0.674856369	-1.312515324	0.001764003	0.003573851	down	yes	0.338245222	0.344446793	0.114515119	0.770450317	0.631714093	0.622404697	2	116346426	116355031	+	ENSGALG00000055117	protein_coding	GO:0001502|cartilage condensation; GO:0001822|kidney development; GO:0001937|negative regulation of endothelial cell proliferation; GO:0002063|chondrocyte development; GO:0007155|cell adhesion; GO:0014846|esophagus smooth muscle contraction; GO:0016525|negative regulation of angiogenesis; GO:0030177|positive regulation of Wnt signaling pathway; GO:0030201|heparan sulfate proteoglycan metabolic process; GO:0030336|negative regulation of cell migration; GO:0030513|positive regulation of BMP signaling pathway; GO:0035860|glial cell-derived neurotrophic factor receptor signaling pathway; GO:0036022|limb joint morphogenesis; GO:0040037|negative regulation of fibroblast growth factor receptor signaling pathway; GO:0048010|vascular endothelial growth factor receptor signaling pathway; GO:0048661|positive regulation of smooth muscle cell proliferation; GO:0048706|embryonic skeletal system development; GO:0051216|cartilage development; GO:0060070|canonical Wnt signaling pathway; GO:0060348|bone development; GO:0060384|innervation; GO:0060686|negative regulation of prostatic bud formation	GO:0005615|extracellular space; GO:0005783|endoplasmic reticulum; GO:0005794|Golgi apparatus; GO:0005795|Golgi stack; GO:0009986|cell surface; GO:0045121|membrane raft	GO:0004065|arylsulfatase activity; GO:0005509|calcium ion binding; GO:0008449|N-acetylglucosamine-6-sulfatase activity	ko:K14607|SULF	--	2804	XP_019469904.1	XP_019469904.1 PREDICTED: uncharacterized protein LOC100544547 [Meleagris gallopavo]	sp|Q90XB6|SULF1_COTCO	sp|Q90XB6|SULF1_COTCO Extracellular sulfatase Sulf-1 OS=Coturnix coturnix GN=SULF1 PE=1 SV=1	_	_	_	_	_	_