motif_id sequence_name start stop strand score p-value matched_sequence ID Target_Enhancers Observations Is_mosaic_MF Closest_Gene TFBS driver_targeted Enhancer_ID Class_alteration HIC1_HUMAN.H11MO.0.C 7_101460362_T_G_WT 12 20 + 15.2809 4.06e-06 GGGGTGCCC 7_101460362_T_G {'PRKRIP1', 'SRRT', 'LRWD1', 'ENSG00000259294', 'POLR2J3', 'ENSG00000213385', 'TRIP6', 'POLR2J2', 'CUX1'} 1.0 not_mos CUX1 HIC1 CUX1 {'GH07J101813'} Disruption RARA_HUMAN.H11MO.1.A 4_106068136_G_C_WT 14 23 + 14.5606 2.72e-06 GAGGTCAGAG 4_106068136_G_C {'TET2-AS1', 'TET2', 'PPA2', 'ENSG00000250740', 'RN7SL89P', 'EEF1A1P9'} 1.0 mosaic TET2 RARA TET2 {'GH04J105144'} Disruption RORA_HUMAN.H11MO.0.C 4_106068136_G_C_WT 11 23 + 14.4141 1.54e-06 AACGAGGTCAGAG 4_106068136_G_C {'TET2-AS1', 'TET2', 'PPA2', 'ENSG00000250740', 'RN7SL89P', 'EEF1A1P9'} 1.0 mosaic TET2 RORA TET2 {'GH04J105144'} Disruption RARA_HUMAN.H11MO.0.A 4_106068136_G_C_WT 4 23 + 14.2879 6.22e-06 GGACGAGAACGAGGTCAGAG 4_106068136_G_C {'TET2-AS1', 'TET2', 'PPA2', 'ENSG00000250740', 'RN7SL89P', 'EEF1A1P9'} 1.0 mosaic TET2 RARA TET2 {'GH04J105144'} Disruption NFYB_HUMAN.H11MO.0.A 2_25525626_ATTG_A_WT 11 23 - 13.7541 1.32e-05 GATCCAATCAGAA 2_25525626_ATTG_A {'POMC', 'MIR1301', 'DNAJC27', 'DNMT3A'} 1.0 not_mos DNMT3A NFYB DNMT3A {'GH02J025301'} Disruption E2F4_HUMAN.H11MO.0.A 17_58677295_T_G_MUT 12 24 + 13.5303 1.34e-05 CCGCGCGGGAAAG 17_58677295_T_G {'NDUFB8P2', 'HEATR6', 'DHX40P1', 'RPS6KB1', 'NACA2', 'RPS29P21', 'KRT18P61', 'TBC1D3P1-DHX40P1', 'PPM1D', 'TBC1D3P1', 'TUBD1'} 1.0 not_mos PPM1D E2F4 PPM1D {'GH17J060598'} Creation SMAD2_HUMAN.H11MO.0.A 18_61034619_GGGTGTC_G_WT 19 30 + 13.3485 1.06e-05 TGTCTCCCACTC 18_61034619_GGGTGTC_G {'ENSG00000267390', 'KDSR'} 6.0 not_mos KDSR SMAD2 KDSR {'GH18J063365'} Disruption SMAD2_HUMAN.H11MO.0.A 18_61034625_C_CAT_WT 13 24 + 13.3485 1.06e-05 TGTCTCCCACTC 18_61034625_C_CAT {'ENSG00000267390', 'KDSR'} 2.0 not_mos KDSR SMAD2 KDSR {'GH18J063365'} Disruption MITF_HUMAN.H11MO.0.A 7_101615908_C_T_MUT 11 20 + 13.1515 2.1e-05 TCACGTGCCC 7_101615908_C_T {'CUX1'} 1.0 not_mos CUX1 MITF CUX1 {'GH07J101972'} Creation NFYA_HUMAN.H11MO.0.A 2_25525626_ATTG_A_WT 11 24 - 13.0303 2.15e-05 AGATCCAATCAGAA 2_25525626_ATTG_A {'POMC', 'MIR1301', 'DNAJC27', 'DNMT3A'} 1.0 not_mos DNMT3A NFYA DNMT3A {'GH02J025301'} Disruption E2F3_HUMAN.H11MO.0.A 17_58677295_T_G_MUT 13 23 + 12.7364 1.59e-05 CGCGCGGGAAA 17_58677295_T_G {'NDUFB8P2', 'HEATR6', 'DHX40P1', 'RPS6KB1', 'NACA2', 'RPS29P21', 'KRT18P61', 'TBC1D3P1-DHX40P1', 'PPM1D', 'TBC1D3P1', 'TUBD1'} 1.0 not_mos PPM1D E2F3 PPM1D {'GH17J060598'} Creation KLF8_HUMAN.H11MO.0.C 19_10872103_A_G_MUT 12 20 + 12.7236 3.5e-05 CATGGGGTG 19_10872103_A_G {'MIR199A1', 'SLC44A2', 'CDKN2D', 'MIR4748', 'SMARCA4', 'DNM2', 'MIR638', 'KRI1'} 1.0 mosaic DNM2 KLF8 DNM2 {'GH19J010757'} Creation NFYC_HUMAN.H11MO.0.A 2_25525626_ATTG_A_WT 11 24 - 12.6972 1.92e-05 AGATCCAATCAGAA 2_25525626_ATTG_A {'POMC', 'MIR1301', 'DNAJC27', 'DNMT3A'} 1.0 not_mos DNMT3A NFYC DNMT3A {'GH02J025301'} Disruption NR1H3_HUMAN.H11MO.1.B 4_106068136_G_C_WT 13 22 + 12.5303 1.75e-05 CGAGGTCAGA 4_106068136_G_C {'TET2-AS1', 'TET2', 'PPA2', 'ENSG00000250740', 'RN7SL89P', 'EEF1A1P9'} 1.0 mosaic TET2 NR1H3 TET2 {'GH04J105144'} Disruption SNAI1_HUMAN.H11MO.0.C 7_101500165_G_A_MUT 14 21 - 12.4228 6.59e-05 GCAGGTGT 7_101500165_G_A {'PRKRIP1', 'SPDYE2B', 'ENSG00000259294', 'SPDYE2', 'CUX1', 'SH2B2'} 1.0 not_mos CUX1 SNAI1 CUX1 {'GH07J101855'} Creation NFIC_HUMAN.H11MO.1.A 2_100626006_T_C_WT 15 23 - 12.303 1.21e-05 TCCTGGCAC 2_100626006_T_C {'AFF3', 'ENSG00000230393'} 1.0 mosaic AFF3 NFIC AFF3 {'GH02J100008'} Disruption SALL4_HUMAN.H11MO.0.B 20_57465938_A_C_MUT 11 20 - 12.2959 3.5700000000000014e-05 GGAGGGTGGA 20_57465938_A_C {'ENSG00000227282', 'ANKRD60', 'PIEZO1P2', 'ENSG00000270279', 'LOC101927932', 'ENSG00000270951', 'GNAS', 'PPP4R1L', 'NELFCD'} 1.0 not_mos GNAS SALL4 GNAS {'GH20J058887'} Creation ESR1_HUMAN.H11MO.1.A 4_106068136_G_C_WT 13 22 + 12.2879 3.2899999999999987e-05 CGAGGTCAGA 4_106068136_G_C {'TET2-AS1', 'TET2', 'PPA2', 'ENSG00000250740', 'RN7SL89P', 'EEF1A1P9'} 1.0 mosaic TET2 ESR1 TET2 {'GH04J105144'} Disruption SMAD4_HUMAN.H11MO.0.B 18_61034619_GGGTGTC_G_WT 18 30 + 12.2245 3.03e-05 GTGTCTCCCACTC 18_61034619_GGGTGTC_G {'ENSG00000267390', 'KDSR'} 6.0 not_mos KDSR SMAD4 KDSR {'GH18J063365'} Disruption SMAD4_HUMAN.H11MO.0.B 18_61034625_C_CAT_WT 12 24 + 12.2245 3.03e-05 GTGTCTCCCACTC 18_61034625_C_CAT {'ENSG00000267390', 'KDSR'} 2.0 not_mos KDSR SMAD4 KDSR {'GH18J063365'} Disruption RARA_HUMAN.H11MO.1.A 17_58678199_A_C_MUT 9 18 - 12.197 3.65e-05 GAGGGCAGCG 17_58678199_A_C {'NDUFB8P2', 'HEATR6', 'DHX40P1', 'RPS6KB1', 'NACA2', 'RPS29P21', 'KRT18P61', 'TBC1D3P1-DHX40P1', 'PPM1D', 'TBC1D3P1', 'TUBD1'} 1.0 not_mos PPM1D RARA PPM1D {'GH17J060598'} Creation TAL1_HUMAN.H11MO.1.A 7_101500165_G_A_MUT 13 27 - 12.1364 3.01e-05 CGGCTGGCAGGTGTG 7_101500165_G_A {'PRKRIP1', 'SPDYE2B', 'ENSG00000259294', 'SPDYE2', 'CUX1', 'SH2B2'} 1.0 not_mos CUX1 TAL1 CUX1 {'GH07J101855'} Creation WT1_HUMAN.H11MO.1.B 7_101382908_C_A_MUT 11 21 + 12.0921 3.71e-05 GAGGGAGGGTC 7_101382908_C_A {'PRKRIP1', 'SRRT', 'POLR2J3', 'POLR2J2', 'CLDN15', 'CUX1'} 1.0 not_mos CUX1 WT1 CUX1 {'GH07J101739'} Creation VDR_HUMAN.H11MO.0.A 18_61034619_GGGTGTC_G_WT 7 22 + 12.0244 3.04e-05 GGGGTCGCCGGGTGTC 18_61034619_GGGTGTC_G {'ENSG00000267390', 'KDSR'} 6.0 not_mos KDSR VDR KDSR {'GH18J063365'} Disruption NFKB1_HUMAN.H11MO.1.B 18_61034625_C_CAT_WT 10 20 - 11.9697 3.21e-05 GGGAGACACCC 18_61034625_C_CAT {'ENSG00000267390', 'KDSR'} 2.0 not_mos KDSR NFKB1 KDSR {'GH18J063365'} Disruption NFKB1_HUMAN.H11MO.1.B 18_61034619_GGGTGTC_G_WT 16 26 - 11.9697 3.21e-05 GGGAGACACCC 18_61034619_GGGTGTC_G {'ENSG00000267390', 'KDSR'} 6.0 not_mos KDSR NFKB1 KDSR {'GH18J063365'} Disruption MBD2_HUMAN.H11MO.0.B 9_139424788_G_C_WT 10 20 + 11.9474 5.320000000000001e-05 GGCTCCGGGGA 9_139424788_G_C {'DNLZ', 'ENTR1', 'INPP5E', 'ENSG00000227512', 'NOTCH1', 'PTGDS', 'ANAPC2', 'LCNL1', 'SEC16A', 'MIR4673', 'EXD3', 'AJM1', 'SNHG7', 'CARD9', 'NALT1', 'MAN1B1', 'NACC2', 'NDOR1'} 1.0 mosaic NOTCH1 MBD2 NOTCH1 {'GH09J136524'} Disruption RXRB_HUMAN.H11MO.0.C 4_106068136_G_C_WT 13 22 + 11.8681 3.76e-05 CGAGGTCAGA 4_106068136_G_C {'TET2-AS1', 'TET2', 'PPA2', 'ENSG00000250740', 'RN7SL89P', 'EEF1A1P9'} 1.0 mosaic TET2 RXRB TET2 {'GH04J105144'} Disruption VDR_HUMAN.H11MO.1.A 19_10829445_A_C_MUT 11 19 - 11.8485 5.36e-05 CGGGTTCAC 19_10829445_A_C {'TYK2', 'S1PR5', 'SLC44A2', 'C19orf38', 'PRKCSH', 'CDKN2D', 'SMARCA4', 'TIMM29', 'DNMT1', 'DNM2', 'S1PR2', 'PPAN', 'ZNF846', 'SWSAP1', 'KRI1', 'QTRT1', 'CARM1', 'ZNF627', 'UBE2L4', 'EIF3G', 'MIR638', 'LOC100419831', 'HNRNPA1P10', 'ILF3-DT', 'ICAM3', 'ATG4D', 'RAVER1', 'DOCK6', 'FBXL12', 'ILF3'} 1.0 not_mos DNM2 VDR DNM2 {'GH19J010717'} Creation FLI1_HUMAN.H11MO.0.A 20_57465938_A_C_MUT 10 27 - 11.8333 3.14e-05 GAGAGCAGGAGGGTGGAA 20_57465938_A_C {'ENSG00000227282', 'ANKRD60', 'PIEZO1P2', 'ENSG00000270279', 'LOC101927932', 'ENSG00000270951', 'GNAS', 'PPP4R1L', 'NELFCD'} 1.0 not_mos GNAS FLI1 GNAS {'GH20J058887'} Creation KLF5_HUMAN.H11MO.0.A 7_101501582_T_G_MUT 13 26 + 11.8333 3.47e-05 GGGGTGGTGGTGGG 7_101501582_T_G {'PRKRIP1', 'SPDYE2B', 'ENSG00000259294', 'SPDYE2', 'CUX1', 'SH2B2'} 1.0 not_mos CUX1 KLF5 CUX1 {'GH07J101855'} Creation RXRA_HUMAN.H11MO.1.A 4_106068136_G_C_WT 12 21 + 11.6735 4.5e-05 ACGAGGTCAG 4_106068136_G_C {'TET2-AS1', 'TET2', 'PPA2', 'ENSG00000250740', 'RN7SL89P', 'EEF1A1P9'} 1.0 mosaic TET2 RXRA TET2 {'GH04J105144'} Disruption VDR_HUMAN.H11MO.1.A 4_106068136_G_C_WT 13 21 + 11.6364 6.59e-05 CGAGGTCAG 4_106068136_G_C {'TET2-AS1', 'TET2', 'PPA2', 'ENSG00000250740', 'RN7SL89P', 'EEF1A1P9'} 1.0 mosaic TET2 VDR TET2 {'GH04J105144'} Disruption SALL4_HUMAN.H11MO.0.B 19_10872103_A_G_MUT 13 22 + 11.6122 5.600000000000001e-05 ATGGGGTGGG 19_10872103_A_G {'MIR199A1', 'SLC44A2', 'CDKN2D', 'MIR4748', 'SMARCA4', 'DNM2', 'MIR638', 'KRI1'} 1.0 mosaic DNM2 SALL4 DNM2 {'GH19J010757'} Creation IKZF1_HUMAN.H11MO.0.C 7_101387142_T_C_MUT 12 19 - 11.5488 5.86e-05 GTGGGAGG 7_101387142_T_C {'PRKRIP1', 'SRRT', 'POLR2J3', 'POLR2J2', 'CLDN15', 'CUX1'} 1.0 not_mos CUX1 IKZF1 CUX1 {'GH07J101739'} Creation PPARA_HUMAN.H11MO.1.B 4_106068136_G_C_WT 13 21 + 11.5354 5.45e-05 CGAGGTCAG 4_106068136_G_C {'TET2-AS1', 'TET2', 'PPA2', 'ENSG00000250740', 'RN7SL89P', 'EEF1A1P9'} 1.0 mosaic TET2 PPARA TET2 {'GH04J105144'} Disruption ZFX_HUMAN.H11MO.0.A 9_4985447_C_T_WT 11 20 - 11.3333 8.06e-05 CCAGGCCTCT 9_4985447_C_T {'MIR101-2', 'CSNK1G2P1', 'ENSG00000228165', 'MTCO1P11', 'MTND6P5', 'JAK2'} 1.0 mosaic JAK2 ZFX JAK2 {'GH09J004983'} Disruption KLF6_HUMAN.H11MO.0.A 7_101501582_T_G_MUT 10 28 + 11.0758 5.3799999999999986e-05 TTGGGGGTGGTGGTGGGGA 7_101501582_T_G {'PRKRIP1', 'SPDYE2B', 'ENSG00000259294', 'SPDYE2', 'CUX1', 'SH2B2'} 1.0 not_mos CUX1 KLF6 CUX1 {'GH07J101855'} Creation FOXO1_HUMAN.H11MO.0.A 17_58679430_T_A_WT 12 23 + 11.0273 6.440000000000001e-05 AGTCTGTTTTCC 17_58679430_T_A {'NDUFB8P2', 'HEATR6', 'DHX40P1', 'RPS6KB1', 'NACA2', 'RPS29P21', 'KRT18P61', 'TBC1D3P1-DHX40P1', 'PPM1D', 'TBC1D3P1', 'TUBD1'} 1.0 not_mos PPM1D FOXO1 PPM1D {'GH17J060598'} Disruption FOXO1_HUMAN.H11MO.0.A 17_58679431_G_T_WT 11 22 + 11.0273 6.440000000000001e-05 AGTCTGTTTTCC 17_58679431_G_T {'NDUFB8P2', 'HEATR6', 'DHX40P1', 'RPS6KB1', 'NACA2', 'RPS29P21', 'KRT18P61', 'TBC1D3P1-DHX40P1', 'PPM1D', 'TBC1D3P1', 'TUBD1'} 1.0 not_mos PPM1D FOXO1 PPM1D {'GH17J060598'} Disruption E2F4_HUMAN.H11MO.0.A 12_46122593_C_T_WT 11 23 + 10.9697 7.37e-05 CGGGCCGGGGACG 12_46122593_C_T {'SCAF11', 'LINC00938', 'ARID2', 'KNOP1P2'} 1.0 mosaic ARID2 E2F4 ARID2 {'GH12J045725'} Disruption SALL4_HUMAN.H11MO.0.B 15_52821533_A_C_WT 13 22 - 10.9592 9.24e-05 CCGGGGTGTG 15_52821533_A_C {'ENSG00000259935', 'ENSG00000259712', 'ENSG00000260618', 'MYO5A', 'EEF1B2P1', 'ARPP19'} 1.0 not_mos MYO5A SALL4 MYO5A {'GH15J052527'} Disruption ATF3_HUMAN.H11MO.0.A 7_101525872_C_T_WT 9 19 - 10.9495 8.27e-05 GGTGACGAGAG 7_101525872_C_T {'FAM185A', 'ENSG00000213385', 'ENSG00000272219', 'CUX1', 'SH2B2'} 1.0 not_mos CUX1 ATF3 CUX1 {'GH07J101879'} Disruption HSF1_HUMAN.H11MO.0.A 3_38180709_G_A_WT 14 28 + 10.9091 5.21e-05 GAGAAAGGTCCGGAT 3_38180709_G_A {'ENSG00000201965', 'OXSR1', 'ACAA1', 'MYD88'} 1.0 not_mos MYD88 HSF1 MYD88 {'GH03J038129'} Disruption E2F5_HUMAN.H11MO.0.B 9_139424788_G_C_MUT 14 23 + 10.8624 6.03e-05 CCCGGGAAAC 9_139424788_G_C {'DNLZ', 'ENTR1', 'INPP5E', 'ENSG00000227512', 'NOTCH1', 'PTGDS', 'ANAPC2', 'LCNL1', 'SEC16A', 'MIR4673', 'EXD3', 'AJM1', 'SNHG7', 'CARD9', 'NALT1', 'MAN1B1', 'NACC2', 'NDOR1'} 1.0 mosaic NOTCH1 E2F5 NOTCH1 {'GH09J136524'} Creation CLOCK_HUMAN.H11MO.0.C 19_10929298_C_T_MUT 16 29 - 10.8403 4.49e-05 CTGGCAAGTGGGGA 19_10929298_C_T {'TYK2', 'S1PR5', 'MIR199A1', 'SLC44A2', 'C19orf38', 'ILF3', 'CDKN2D', 'SMARCA4', 'TIMM29', 'DNM2', 'PDE4A', 'KRI1', 'CARM1', 'ZNF627', 'EIF3G', 'ILF3-DT', 'ICAM3', 'ATG4D', 'ZNF441', 'FBXL12', 'PPAN'} 2.0 mosaic DNM2 CLOCK DNM2 {'GH19J010808'} Creation IRF7_HUMAN.H11MO.0.C 20_57483545_A_G_WT 8 17 + 10.8261 9.89e-05 AAAAGTAAAA 20_57483545_A_G {'GNAS', 'LOC101927932', 'NELFCD'} 1.0 mosaic GNAS IRF7 GNAS {'GH20J058904'} Disruption RXRB_HUMAN.H11MO.0.C 7_101615908_C_T_MUT 14 23 - 10.8242 8.22e-05 TGAGGGCACG 7_101615908_C_T {'CUX1'} 1.0 not_mos CUX1 RXRB CUX1 {'GH07J101972'} Creation NFKB2_HUMAN.H11MO.0.B 18_61034625_C_CAT_WT 10 20 - 10.8182 6.91e-05 GGGAGACACCC 18_61034625_C_CAT {'ENSG00000267390', 'KDSR'} 2.0 not_mos KDSR NFKB2 KDSR {'GH18J063365'} Disruption NFKB2_HUMAN.H11MO.0.B 18_61034619_GGGTGTC_G_WT 16 26 - 10.8182 6.91e-05 GGGAGACACCC 18_61034619_GGGTGTC_G {'ENSG00000267390', 'KDSR'} 6.0 not_mos KDSR NFKB2 KDSR {'GH18J063365'} Disruption TBX3_HUMAN.H11MO.0.C 2_96931282_T_C_WT 11 21 + 10.7576 8.68e-05 GGGGGTGGGAC 2_96931282_T_C {'TMEM127', 'LMAN2L', 'STARD7-AS1', 'KCNIP3', 'NCAPH', 'CNNM3', 'SNRNP200', 'KANSL3', 'CIAO1', 'ANKRD36', 'ENSG00000230747', 'DUSP2', 'ASTL', 'ITPRIPL1'} 1.0 not_mos TMEM127 TBX3 TMEM127 {'GH02J096263'} Disruption PBX3_HUMAN.H11MO.0.A 9_4986098_GGAAGCGTGTGAAGA_G_WT 28 38 + 10.7258 7.87e-05 AGAGAGGCAGG 9_4986098_GGAAGCGTGTGAAGA_G {'MIR101-2', 'CSNK1G2P1', 'ENSG00000228165', 'MTCO1P11', 'MTND6P5', 'JAK2'} 1.0 not_mos JAK2 PBX3 JAK2 {'GH09J004983'} Disruption TBX3_HUMAN.H11MO.0.C 20_57465938_A_C_MUT 9 19 - 10.6818 9.49e-05 GAGGGTGGAAA 20_57465938_A_C {'ENSG00000227282', 'ANKRD60', 'PIEZO1P2', 'ENSG00000270279', 'LOC101927932', 'ENSG00000270951', 'GNAS', 'PPP4R1L', 'NELFCD'} 1.0 not_mos GNAS TBX3 GNAS {'GH20J058887'} Creation E2F4_HUMAN.H11MO.1.A 9_139440038_A_G_MUT 7 20 - 10.6667 9.29e-05 GGCGCGGGGTTCTG 9_139440038_A_G {'C9orf163', 'INPP5E', 'ENSG00000227512', 'NOTCH1', 'ENTR1', 'ANAPC2', 'MIR4674', 'SEC16A', 'ABCA2', 'EXD3', 'FUT7', 'SNHG7', 'CARD9', 'NALT1', 'MAN1B1', 'NACC2', 'SNAPC4'} 1.0 mosaic NOTCH1 E2F4 NOTCH1 {'GH09J136537'} Creation PBX3_HUMAN.H11MO.0.A 2_96930284_G_A_WT 13 23 - 10.5806 8.8e-05 AGATAGACAGC 2_96930284_G_A {'TMEM127', 'LMAN2L', 'STARD7-AS1', 'KCNIP3', 'NCAPH', 'CNNM3', 'SNRNP200', 'KANSL3', 'CIAO1', 'ANKRD36', 'ENSG00000230747', 'DUSP2', 'ASTL', 'ITPRIPL1'} 1.0 not_mos TMEM127 PBX3 TMEM127 {'GH02J096263'} Disruption PATZ1_HUMAN.H11MO.1.C 7_101382908_C_A_MUT 12 20 + 10.5606 9.33e-05 AGGGAGGGT 7_101382908_C_A {'PRKRIP1', 'SRRT', 'POLR2J3', 'POLR2J2', 'CLDN15', 'CUX1'} 1.0 not_mos CUX1 PATZ1 CUX1 {'GH07J101739'} Creation NR1D1_HUMAN.H11MO.0.B 4_106068136_G_C_WT 7 25 + 10.5495 8.329999999999999e-05 CGAGAACGAGGTCAGAGCG 4_106068136_G_C {'TET2-AS1', 'TET2', 'PPA2', 'ENSG00000250740', 'RN7SL89P', 'EEF1A1P9'} 1.0 mosaic TET2 NR1D1 TET2 {'GH04J105144'} Disruption E2F1_HUMAN.H11MO.0.A 7_101461128_T_G_MUT 12 25 + 10.4472 9.12e-05 GGTGGGCGTGAAGA 7_101461128_T_G {'PRKRIP1', 'SRRT', 'LRWD1', 'ENSG00000259294', 'POLR2J3', 'ENSG00000213385', 'TRIP6', 'POLR2J2', 'CUX1'} 1.0 not_mos CUX1 E2F1 CUX1 {'GH07J101813'} Creation LYL1_HUMAN.H11MO.0.A 2_25525521_G_A_WT 13 26 + 10.1791 8.94e-05 CCTGCTGCTTCTGA 2_25525521_G_A {'POMC', 'MIR1301', 'DNAJC27', 'DNMT3A'} 1.0 mosaic DNMT3A LYL1 DNMT3A {'GH02J025301'} Disruption KLF6_HUMAN.H11MO.0.A 6_79788283_T_G_MUT 5 23 + 10.1061 9.74e-05 CCGGGGACGGTGCCGCGGA 6_79788283_T_G {'PHIP', 'ENSG00000233835', 'LCA5', 'IRAK1BP1', 'LOC100419073'} 5.0 not_mos PHIP KLF6 PHIP {'GH06J079075'} Creation KLF5_HUMAN.H11MO.0.A 10_43617228_A_G_MUT 9 22 + 10.0909 9.31e-05 AGGCTGGGGCTCCA 10_43617228_A_G {'CSGALNACT2', 'RET', 'HNRNPF'} 1.0 not_mos RET KLF5 RET {'GH10J043120'} Creation SP3_HUMAN.H11MO.0.B 7_101501582_T_G_MUT 8 27 + 10.0275 8.87e-05 TTTTGGGGGTGGTGGTGGGG 7_101501582_T_G {'PRKRIP1', 'SPDYE2B', 'ENSG00000259294', 'SPDYE2', 'CUX1', 'SH2B2'} 1.0 not_mos CUX1 SP3 CUX1 {'GH07J101855'} Creation IRF3_HUMAN.H11MO.0.B 4_106068731_GT_G_WT 13 32 - 10.0234 8.35e-05 TTAAGGAAAAAAAAAACCCA 4_106068731_GT_G {'TET2-AS1', 'TET2', 'PPA2', 'ENSG00000250740', 'RN7SL89P', 'EEF1A1P9'} 1.0 not_mos TET2 IRF3 TET2 {'GH04J105144'} Disruption SP4_HUMAN.H11MO.0.A 20_57465938_A_C_MUT 5 24 - 9.97581 9.18e-05 AGCAGGAGGGTGGAAAAAGC 20_57465938_A_C {'ENSG00000227282', 'ANKRD60', 'PIEZO1P2', 'ENSG00000270279', 'LOC101927932', 'ENSG00000270951', 'GNAS', 'PPP4R1L', 'NELFCD'} 1.0 not_mos GNAS SP4 GNAS {'GH20J058887'} Creation THAP1_HUMAN.H11MO.0.C 20_57465938_A_C_MUT 10 31 + 9.93662 8.49e-05 TTCCACCCTCCTGCTCTCTGGC 20_57465938_A_C {'ENSG00000227282', 'ANKRD60', 'PIEZO1P2', 'ENSG00000270279', 'LOC101927932', 'ENSG00000270951', 'GNAS', 'PPP4R1L', 'NELFCD'} 1.0 not_mos GNAS THAP1 GNAS {'GH20J058887'} Creation VEZF1_HUMAN.H11MO.0.C 7_101501582_T_G_MUT 6 27 + 9.79167 9.76e-05 GGTTTTGGGGGTGGTGGTGGGG 7_101501582_T_G {'PRKRIP1', 'SPDYE2B', 'ENSG00000259294', 'SPDYE2', 'CUX1', 'SH2B2'} 1.0 not_mos CUX1 VEZF1 CUX1 {'GH07J101855'} Creation USF2_HUMAN.H11MO.0.A 8_101734762_C_A_WT 7 25 - 9.75758 5.83e-05 CGCGCACGTGGGGGGTGGT 8_101734762_C_A {'ENSG00000271882', 'SNX31', 'PABPC1'} 1.0 not_mos PABPC1 USF2 PABPC1 {'GH08J100718'} Disruption NR1I3_HUMAN.H11MO.0.C 7_101525872_C_T_WT 4 21 - 9.61111 9.37e-05 AAGGTGACGAGAGGTGCT 7_101525872_C_T {'FAM185A', 'ENSG00000213385', 'ENSG00000272219', 'CUX1', 'SH2B2'} 1.0 not_mos CUX1 NR1I3 CUX1 {'GH07J101879'} Disruption SP2_HUMAN.H11MO.0.A 8_101733971_A_G_MUT 7 28 + 9.5935 7.290000000000001e-05 GGCCGCAGAGCGGGGTCGATCC 8_101733971_A_G {'ENSG00000271882', 'SNX31', 'PABPC1'} 1.0 not_mos PABPC1 SP2 PABPC1 {'GH08J100718'} Creation RFX1_HUMAN.H11MO.0.B 20_57464449_T_G_WT 9 30 + 9.24242 7.159999999999999e-05 GTGCGAGTCGCCCGGCGCAGGC 20_57464449_T_G {'ENSG00000227282', 'ANKRD60', 'PIEZO1P2', 'ENSG00000270279', 'LOC101927932', 'ENSG00000270951', 'GNAS', 'PPP4R1L', 'NELFCD'} 1.0 not_mos GNAS RFX1 GNAS {'GH20J058887'} Disruption USF2_HUMAN.H11MO.0.A 8_101734762_C_A_WT 12 30 + 9.10606 7.609999999999999e-05 CCCCCACGTGCGCGGCCGC 8_101734762_C_A {'ENSG00000271882', 'SNX31', 'PABPC1'} 1.0 not_mos PABPC1 USF2 PABPC1 {'GH08J100718'} Disruption KLF9_HUMAN.H11MO.0.C 15_52821465_C_T_WT 11 25 - 8.957139999999997 5.39e-05 GGCGGCGGCGGGGCC 15_52821465_C_T {'ENSG00000259935', 'ENSG00000259712', 'ENSG00000260618', 'MYO5A', 'EEF1B2P1', 'ARPP19'} 1.0 not_mos MYO5A KLF9 MYO5A {'GH15J052527'} Disruption ZNF76_HUMAN.H11MO.0.C 4_106068206_G_A_WT 6 27 + 8.52846 9.02e-05 CGGGCTTCCAGGGACTGGGGAG 4_106068206_G_A {'TET2-AS1', 'TET2', 'PPA2', 'ENSG00000250740', 'RN7SL89P', 'EEF1A1P9'} 1.0 not_mos TET2 ZNF76 TET2 {'GH04J105144'} Disruption USF2_HUMAN.H11MO.0.A 7_101615908_C_T_MUT 3 21 - 8.42424 9.95e-05 AGGGCACGTGAATACAGCA 7_101615908_C_T {'CUX1'} 1.0 not_mos CUX1 USF2 CUX1 {'GH07J101972'} Creation CTCF_HUMAN.H11MO.0.A 15_52821533_A_C_MUT 7 25 - 8.393939999999999 6.25e-05 CGCCCGGGGGGTGCCGCGC 15_52821533_A_C {'ENSG00000259935', 'ENSG00000259712', 'ENSG00000260618', 'MYO5A', 'EEF1B2P1', 'ARPP19'} 1.0 not_mos MYO5A CTCF MYO5A {'GH15J052527'} Creation WT1_HUMAN.H11MO.0.C 18_61034625_C_CAT_WT 7 26 - 8.25758 9.9e-05 GGGAGTGGGAGACACCCGGC 18_61034625_C_CAT {'ENSG00000267390', 'KDSR'} 2.0 not_mos KDSR WT1 KDSR {'GH18J063365'} Disruption ZIM3_HUMAN.H11MO.0.C 7_101796764_T_G_WT 10 28 + 8.121210000000001 8.41e-05 GTGTCCTCCTGTTGCTGCT 7_101796764_T_G {'ENSG00000213385', 'CRYZP1', 'ENSG00000252824', 'POLR2J2', 'CUX1'} 1.0 mosaic CUX1 ZIM3 CUX1 {'GH07J102150'} Disruption KLF9_HUMAN.H11MO.0.C 20_57465829_A_C_MUT 9 23 - 7.342860000000001 9.81e-05 GCGATGGGGGTGTCT 20_57465829_A_C {'ENSG00000227282', 'ANKRD60', 'PIEZO1P2', 'ENSG00000270279', 'LOC101927932', 'ENSG00000270951', 'GNAS', 'PPP4R1L', 'NELFCD'} 1.0 not_mos GNAS KLF9 GNAS {'GH20J058887'} Creation