Compound_ID;SMILES;Slope of the fluorescent signal at 10 µM;DV EC50 (µM);I/I0;Maximal currents EC50 (µM);Seizures score (Luttjohann's scale) ;Latency to maximal seizures (s);Survival rate in PTZ seizure model
RET;FC1=CC=C(C=C1)CNC2=CC=C(C(N)=C2)NC(OCC)=O;0.0270±0.0052;2.5±1.8 ;0.99±0.15;;7.3±0.3 (at 3 mg/Kg);1041.4±223.2 (at 3 mg/Kg);40% (at 3 mg/Kg)
RL-81;FC1=CC=C(C=C1)CNC2=CC=C(C(N)=C2F)NC(OCC)=O;0.0272±0.0014;0.24±0.06 ;1.6±0.2;0.27±0.04;;;
2;CCCCCCC(NC1=CC=C(NCC2=CC=C(C(F)(F)F)C=C2)C=C1)=O;0.0326±0.0063;;;;;;
13;CCCCCCC(NC1=CC=C(NCC2=CC=C(C(F)(F)F)C=C2)C=C1N)=O;0.0443±0.0049;;;;;;
14;CCCCCCCC(NC1=CC=C(NCC2=CC=C(C(F)(F)F)C=C2)C=C1N)=O;0.0563±0.0039;;;;;;
15;CCCCCCCCCC(NC1=CC=C(NCC2=CC=C(C(F)(F)F)C=C2)C=C1N)=O;0.0261±0.0030;;;;;;
16;CCCCCCCCCCCC(NC1=CC=C(NCC2=CC=C(C(F)(F)F)C=C2)C=C1N)=O;0.0084±0.0004;;;;;;
17;CC(C)(C)CC(NC1=CC=C(NCC2=CC=C(C(F)(F)F)C=C2)C=C1N)=O;0.0512±0.0040;;;;;;
18;O=C(C1CC1)NC2=CC=C(NCC3=CC=C(C(F)(F)F)C=C3)C=C2N;0.0346±0.0078;;;;;;
19;O=C(NC1=CC=C(NCC2=CC=C(C(F)(F)F)C=C2)C=C1N)CCC3CCCCC3;0.0452±0.0077;;;;;;
20;O=C(NC1=CC=C(NCC2=CC=C(C(F)(F)F)C=C2)C=C1N)COCCOC;0.0062±0.0005;;;;;;
23;CC(C)(C)CC(NC1=CC=C(NCC2=CC=C(C(F)(F)F)C=C2)C=C1N3CCCC3)=O;0.0772±0.0036;;;;;;
24;CC(C)(C)CC(NC1=CC=C(NCC2=CC=C(C(F)(F)F)C=C2)C=C1N3CCCCC3)=O;0.0591±0.0043;;;;;;
25;CCCCCCC(NC1=CC=C(N(C)CC2=CC=C(C(F)(F)F)C=C2)C=C1N)=O;0.0637±0.0033;;;;;;
26;CC(C)(C)CC(NC1=CC=C(N(C)CC2=CC=C(C(F)(F)F)C=C2)C=C1N)=O;0.0721±0.0034;;;;;;
27;CCCCCCC(NC1=CC=C(N(CCC)CC2=CC=C(C(F)(F)F)C=C2)C=C1N)=O;0.0363±0.0052;;;;;;
28;CCCCCCC(NC1=CC=C(N(CC2=CC=C(C(F)(F)F)C=C2)C(C)=O)C=C1N)=O;0.0138±0.0024;;;;;;
31;CCCCCCC(NC1=CC=C(OCC2=CC=C(C(F)(F)F)C=C2)C=C1N)=O;0.0057±0.0005;;;;;;
41;CCCCCCC(NC1=CC=C(NCC2=CC=CC=C2)C=C1N)=O;0.0476±0.0030;;;;;;
42;CCCCCCC(NC1=CC=C(NCCC2=CC=C(F)C=C2)C=C1N)=O;0.0098±0.0010;;;;;;
43;CC(C)(C)CC(NC1=CC=C(NCC2=C(F)C=CC=C2F)C=C1N)=O;0.0534±0.0028;;;;;;
47;CCCCCCC(NC1=CC=C(NCC2=NC=CC=C2)C=C1N)=O;0.0071±0.0004;;;;;;
51;CCCCCCC(NC1=CC=C(NCC2=CC=NC=C2)C=C1N)=O;0.0063±0.0002;;;;;;
52;CCCCCCC(NC1=CC=C(NCC2=CC=CC=C2F)C=C1N)=O;0.0448±0.0035;;;;;;
57;CCCCCCC(NC1=CC=C(NCC2=CC=C(O)C=C2)C=C1N)=O;0.0068±0.0003;;;;;;
59;CCCCCCC(NC1=CC=C(NCC2=CC=C(C(F)(F)F)C=C2)C(F)=C1N)=O;0.0345±0.0026;;;;;;
60;CC(C)(C)CC(NC1=CC=C(NCC2=CC=C(C(F)(F)F)C=C2)C(F)=C1N)=O;0.0594±0.0026;0.15±0.03;2.1±0.3;0.06±0.01;6.0±0.4 (at 0.3 mg/Kg);1159.7±169.4 (at 0.3 mg/Kg);87%  (at 0.3 mg/Kg)
67;CCCCCCC(NC1=CC=C(CCC2=CC=C(C(F)(F)F)C=C2)C=C1N)=O;0.0087±0.0002;;;;;;
68;CC(C)(C)CC(NC1=CC=C(CCC2=CC=C(C(F)(F)F)C=C2)C=C1N)=O;0.0073±0.0005;;;;;;
71;O=C(NCCCCCC)C1=CC=C(NCC2=CC=C(C(F)(F)F)C=C2)C=C1N;0.0066±0.0006;;;;;;