rxns type rxnEq subSys 1 3ISPVShc AdrenalGland-TM pravastatin[c] => 3-alpha-iso-pravastatin[c] Drug metabolism 2 C10CRNtr AdrenalGland-TM Decanoyl Carnitine[s] <=> Decanoyl Carnitine[c] Transport reactions 3 DCMPtm AdrenalGland-TM dCMP[m] <=> dCMP[c] Transport reactions 4 DCMPtr AdrenalGland-TM dCMP[s] <=> dCMP[c] Transport reactions 5 EX_c10crn[e] AdrenalGland-TM Decanoyl Carnitine[s] <=> Decanoyl Carnitine[x] Exchange/demand reactions 6 EX_dcmp[e] AdrenalGland-TM dCMP[s] <=> dCMP[x] Exchange/demand reactions 7 HMR_5232 AdrenalGland-TM HDL remnant[s] => HDL remnant[l] Transport reactions 8 HMR_5233 AdrenalGland-TM HDL remnant[l] => 2 apoA1[l] + 30 H+[l] + 90 PC-LD pool[l] + 25 PE-LD pool[l] + 30 PS-LD pool[l] + 75 SM pool[l] Pool reactions 9 HMR_7736 AdrenalGland-TM ATP[c] + 3 beta-alanine[c] + H2O[c] => ADP[c] + 3 beta-alanine[s] + H+[c] + Pi[c] Transport reactions 10 HMR_8902 AdrenalGland-TM GQ1b[c] <=> GQ1b[g] Transport reactions 11 TMDOATtev AdrenalGland-TM chloride[s] + Torasemide[c] <=> chloride[c] + Torasemide[s] Drug metabolism 12 TRPGLYVALr AdrenalGland-TM 2 H2O[c] + Tryptophanyl-Glycyl-Valine[c] <=> glycine[c] + tryptophan[c] + valine[c] Peptide metabolism 13 5HOXINDOAtr Liver-TM sulfate[c] + 5-hydroxyindoleacetate[s] <=> 5-hydroxyindoleacetate[c] + sulfate[s] Transport reactions 14 CRVSATPthc Liver-TM ATP[c] + H2O[c] + cerivastatin[s] => ADP[c] + H+[c] + Pi[c] + cerivastatin[c] Drug metabolism 15 DDECCRNtr Liver-TM Lauroyl Carnitine[s] <=> Lauroyl Carnitine[c] Transport reactions 16 EX_5hoxindoa[e] Liver-TM 5-hydroxyindoleacetate[s] <=> 5-hydroxyindoleacetate[x] Exchange/demand reactions 17 EX_ddecrn[e] Liver-TM Lauroyl Carnitine[s] <=> Lauroyl Carnitine[x] Exchange/demand reactions 18 FOLOATPtc Liver-TM folate[s] + HCO3-[c] <=> folate[c] + HCO3-[s] Transport reactions 19 HC02195c Liver-TM taurine[c] + Ursodeoxycholyl Coenzyme A[c] => CoA[c] + tauroursodeoxycholate[c] Bile acid biosynthesis 20 HC02196c Liver-TM glycine[c] + Ursodeoxycholyl Coenzyme A[c] => CoA[c] + glycoursodeoxycholate[c] Bile acid biosynthesis 21 HMR_0020 Liver-TM cholesterol-ester pool[c] <=> cholesterol-ester pool[r] Transport reactions 22 HMR_10038 Liver-TM cholesterol-ester pool[r] <=> 0.0004 cholesterol-ester-10,13,16,19-docosa[r] + 0.0004 cholesterol-ester-10,13,16-docosa[r] + 0.0004 cholesterol-ester-10-hepta[r] + 0.0004 cholesterol-ester-11,14,17-eico[r] + 0.0004 cholesterol-ester-11,14-eicosa[r] + 0.0004 cholesterol-ester-11-docose[r] + 0.0004 cholesterol-ester-11-eico[r] + 0.0004 cholesterol-ester-12,15,18,21-tetracosa[r] + 0.0004 cholesterol-ester-13,16,19-doco[r] + 0.0004 cholesterol-ester-13,16-docosa[r] + 0.0004 cholesterol-ester-13-docose[r] + 0.0004 cholesterol-ester-13-eicose[r] + 0.0004 cholesterol-ester-13-octade[r] + 0.0004 cholesterol-ester-15-tetra[r] + 0.0278 cholesterol-ester-4,7,10,13,16,19-doco[r] + 0.0038 cholesterol-ester-4,7,10,13,16-docosa[r] + 0.0116 cholesterol-ester-5,8,11,14,17-eico[r] + 0.0004 cholesterol-ester-5,8,11-eico[r] + 0.0004 cholesterol-ester-5-tetra[r] + 0.0004 cholesterol-ester-6,9,12,15,18,21-tetra[r] + 0.0004 cholesterol-ester-6,9,12,15,18-tetraco[r] + 0.0025 cholesterol-ester-6,9,12,15-octa[r] + 0.0004 cholesterol-ester-6,9-octa[r] + 0.0059 cholesterol-ester-7,10,13,16,19-docosa[r] + 0.0014 cholesterol-ester-7,10,13,16-docosa[r] + 0.0004 cholesterol-ester-7-hexa[r] + 0.0004 cholesterol-ester-7-octade[r] + 0.0004 cholesterol-ester-7-tetrade[r] + 0.0115 cholesterol-ester-8,11,14,17-eico[r] + 0.0004 cholesterol-ester-8,11-eico[r] + 0.0004 cholesterol-ester-9,12,15,18,21-tetra[r] + 0.0004 cholesterol-ester-9,12,15,18-tetraco[r] + 0.0004 cholesterol-ester-9-eicose[r] + 0.0004 cholesterol-ester-9-heptade[r] + 0.0004 cholesterol-ester-9-octa[r] + 0.0004 cholesterol-ester-9-tetrade[r] + 0.1083 cholesterol-ester-arach[r] + 0.025 cholesterol-ester-cis-vac[r] + 0.0215 cholesterol-ester-dihomo-gamma[r] + 0.0004 cholesterol-ester-docosa[r] + 0.0004 cholesterol-ester-eico[r] + 0.0029 cholesterol-ester-gamma-lin[r] + 0.0004 cholesterol-ester-heneico[r] + 0.0004 cholesterol-ester-hepta[r] + 0.0004 cholesterol-ester-hexacosa[r] + 0.0004 cholesterol-ester-hexecose[r] + 0.0004 cholesterol-ester-laur[r] + 0.1915 cholesterol-ester-lin[r] + 0.0084 cholesterol-ester-linolen[r] + 0.0133 cholesterol-ester-myrist[r] + 0.0004 cholesterol-ester-nanode[r] + 0.1545 cholesterol-ester-ol[r] + 0.222 cholesterol-ester-palm[r] + 0.0219 cholesterol-ester-palmn[r] + 0.0004 cholesterol-ester-penta[r] + 0.1498 cholesterol-ester-stea[r] + 0.0004 cholesterol-ester-tetraco[r] + 0.0004 cholesterol-ester-trico[r] + 0.0004 cholesterol-ester-tridec[r] Pool reactions 23 HMR_1668 Liver-TM choloyl-CoA[c] + taurine[c] => CoA[c] + taurocholate[c] Bile acid biosynthesis 24 HMR_1670 Liver-TM choloyl-CoA[c] + glycine[c] => CoA[c] + glycocholate[c] Bile acid biosynthesis 25 HMR_1722 Liver-TM chenodeoxycholoyl-CoA[c] + glycine[c] => CoA[c] + glycochenodeoxycholate[c] Bile acid biosynthesis 26 HMR_1723 Liver-TM chenodeoxycholoyl-CoA[c] + taurine[c] => CoA[c] + taurochenodeoxycholate[c] Bile acid biosynthesis 27 HMR_3520 Liver-TM 4,8-dimethylnonanoylcarnitine[c] + L-carnitine[m] <=> 4,8-dimethylnonanoylcarnitine[m] + L-carnitine[c] Carnitine shuttle (mitochondrial) 28 HMR_3950 Liver-TM 5,10-methylene-THF[c] <=> 5,10-methylene-THF[m] Transport reactions 29 HMR_4873 Liver-TM NH3[c] <=> NH3[s] Transport reactions 30 HMR_5159 Liver-TM 297 ATP[c] + 3 glycyl-tRNA(gly)[c] + 298 H2O[c] + 15 L-alanyl-tRNA(ala)[c] + 4 L-arginyl-tRNA(arg)[c] + 7 L-aspartyl-tRNA(asp)[c] + 6 L-glutaminyl-tRNA(gln)[c] + 5 L-glutamyl-tRNA(glu)[c] + L-histidyl-tRNA(his)[c] + 11 L-leucyl-tRNA(leu)[c] + 6 L-lysyl-tRNA(lys)[c] + 3 L-methionyl-tRNA(met)[c] + 4 L-phenylalanyl-tRNA(phe)[c] + 3 L-prolyl-tRNA(pro)[c] + 12 L-seryl-tRNA(ser)[c] + 5 L-threonyl-tRNA(thr)[c] + 3 L-tryptophanyl-tRNA(trp)[c] + 2 L-tyrosyl-tRNA(tyr)[c] + 9 L-valyl-tRNA(val)[c] => 297 ADP[c] + apoC3[c] + 394 H+[c] + 297 Pi[c] + 15 tRNA(ala)[c] + 4 tRNA(arg)[c] + 7 tRNA(asp)[c] + 6 tRNA(gln)[c] + 5 tRNA(glu)[c] + 3 tRNA(gly)[c] + tRNA(his)[c] + 11 tRNA(leu)[c] + 6 tRNA(lys)[c] + 3 tRNA(met)[c] + 4 tRNA(phe)[c] + 3 tRNA(pro)[c] + 12 tRNA(ser)[c] + 5 tRNA(thr)[c] + 3 tRNA(trp)[c] + 2 tRNA(tyr)[c] + 9 tRNA(val)[c] Protein assembly 31 HMR_5268 Liver-TM apoC1[c] + 82 ATP[c] + 164 H2O[c] => 82 ADP[c] + 5 alanine[c] + 4 arginine[c] + asparagine[c] + 4 aspartate[c] + 8 glutamate[c] + 3 glutamine[c] + 3 glycine[c] + 81 H+[c] + 4 isoleucine[c] + 12 leucine[c] + 9 lysine[c] + 2 methionine[c] + 4 phenylalanine[c] + 82 Pi[c] + 4 proline[c] + 9 serine[c] + 3 threonine[c] + tryptophan[c] + 7 valine[c] Protein degradation 32 HMR_7787 Liver-TM CTP[c] => CTP[s] Transport reactions 33 HMR_8094 Liver-TM noradrenaline[c] + PAPS[c] => H+[c] + norepinephrine sulfate[c] + PAP[c] Tyrosine metabolism 34 HMR_8545 Liver-TM arachidonate[c] + O2[c] => 12(R)-HPETE[c] Eicosanoid metabolism 35 HMR_8659 Liver-TM cholate[s] + HCO3-[c] => cholate[c] + HCO3-[s] Transport reactions 36 HMR_8879 Liver-TM glycocholate[s] + HCO3-[c] => glycocholate[c] + HCO3-[s] Transport reactions 37 LACROX Liver-TM leukoaminochrome[c] + O2[c] => H2O2[c] + 2,3-Dihydro-1H-Indole-5,6-Dione[c] Tyrosine metabolism 38 METHISLYSr Liver-TM 2 H2O[c] + Methionyl-Histidyl-Lysine[c] <=> histidine[c] + lysine[c] + methionine[c] Peptide metabolism 39 PEHSFABPe Liver-TM 2 PE-LD pool[c] <=> 2 PE-LD pool[r] Transport reactions 40 PROPROARGr Liver-TM 2 H2O[c] + Prolyl-Prolyl-Arginine[c] <=> arginine[c] + 2 proline[c] Peptide metabolism 41 PROTRPTHRr Liver-TM 2 H2O[c] + Prolyl-Tryptophanyl-Threonine[c] <=> proline[c] + threonine[c] + tryptophan[c] Peptide metabolism 42 SMVACIDitr Liver-TM simvastatin dihydroxy acid form[c] <=> simvastatin dihydroxy acid form[r] Drug metabolism 43 TRPMETVALr Liver-TM 2 H2O[c] + Tryptophanyl-Methionyl-Valine[c] <=> methionine[c] + tryptophan[c] + valine[c] Peptide metabolism 44 URSCHOLCOAc Liver-TM ATP[c] + CoA[c] + ursodeoxycholate[c] => AMP[c] + PPi[c] + Ursodeoxycholyl Coenzyme A[c] Bile acid biosynthesis 45 AMETt Lung-TM SAM[c] <=> SAM[s] Transport reactions 46 CRVSM24itr Lung-TM cerivastatin-M24[r] <=> cerivastatin-M24[c] Drug metabolism 47 GLYPROt Lung-TM Glycylproline[c] <=> Glycylproline[s] Transport reactions 48 HMR_0018 Lung-TM cholesterol[c] <=> cholesterol[s] Transport reactions 49 HMR_7736 Lung-TM ATP[c] + 3 beta-alanine[c] + H2O[c] => ADP[c] + 3 beta-alanine[s] + H+[c] + Pi[c] Transport reactions 50 HMR_8919 Lung-TM mannose[r] => mannose[c] Transport reactions 51 PEHSFABPe Lung-TM 2 PE-LD pool[c] <=> 2 PE-LD pool[r] Transport reactions 52 3HPVSTETCOAitm LymphNode-TM 3'-S-hydroxy-pravastatin-tetranor-CoA[m] <=> 3'-S-hydroxy-pravastatin-tetranor-CoA[c] Drug metabolism 53 3HPVSTEThc LymphNode-TM H2O[c] + 3'-S-hydroxy-pravastatin-tetranor-CoA[c] => CoA[c] + H+[c] + 3'-S-hydroxy-pravastatin-tetranor[c] Drug metabolism 54 ARGHISTHRr LymphNode-TM 2 H2O[c] + Arginyl-Histidyl-Threonine[c] <=> arginine[c] + histidine[c] + threonine[c] Peptide metabolism 55 BALAVECSEC LymphNode-TM ATP[c] + beta-alanine[c] + H2O[c] => ADP[c] + beta-alanine[s] + H+[c] + Pi[c] Transport reactions 56 BUTSMCT1 LymphNode-TM butyrate[s] + Na+[s] <=> butyrate[c] + Na+[c] Transport reactions 57 CRVSM24itr LymphNode-TM cerivastatin-M24[r] <=> cerivastatin-M24[c] Drug metabolism 58 EX_nfdac[e] LymphNode-TM acid metabolite of nifedipine[s] <=> acid metabolite of nifedipine[x] Exchange/demand reactions 59 GABAVESSEC LymphNode-TM 4-aminobutyrate[c] + ATP[c] + H2O[c] => 4-aminobutyrate[s] + ADP[c] + H+[c] + Pi[c] Transport reactions 60 GLYVESSEC LymphNode-TM ATP[c] + glycine[c] + H2O[c] => ADP[c] + glycine[s] + H+[c] + Pi[c] Transport reactions 61 HMR_0018 LymphNode-TM cholesterol[c] <=> cholesterol[s] Transport reactions 62 HMR_0440 LymphNode-TM phytanic acid[s] => phytanic acid[c] Transport reactions 63 HMR_10127 LymphNode-TM 2 Na+[s] + tauro-hyodeoxycholic acid[s] => 2 Na+[c] + tauro-hyodeoxycholic acid[c] Transport reactions 64 HMR_1629 LymphNode-TM 25(R)THCA-CoA[c] <=> 25(R)THCA-CoA[p] Transport reactions 65 HMR_1631 LymphNode-TM 25(R)THCA-CoA[c] <=> 25(R)THCA-CoA[r] Transport reactions 66 HMR_1767 LymphNode-TM 4-cholesten-7alpha,27-diol-3-one[c] + H+[c] + NADPH[c] + O2[c] => 4-cholesten-7alpha,12alpha,27-triol-3-one[c] + H2O[c] + NADP+[c] Bile acid biosynthesis 67 HMR_1839 LymphNode-TM H+[c] + lithocholate[c] + NADPH[c] + O2[c] => 3alpha,12alpha-dihydroxy-5beta-cholanate[c] + H2O[c] + NADP+[c] Bile acid biosynthesis 68 HMR_1867 LymphNode-TM glycochenodeoxycholate[s] + 2 Na+[s] => glycochenodeoxycholate[c] + 2 Na+[c] Bile acid recycling 69 HMR_2140 LymphNode-TM (24R)-24,25-dihydroxycalciol[m] + H+[m] + NADH[m] + O2[m] => calcitetrol[m] + H2O[m] + NAD+[m] Vitamin D metabolism 70 HMR_4171 LymphNode-TM GDP[c] + H+[c] + PEP[c] => GTP[c] + pyruvate[c] Purine metabolism 71 HMR_4193 LymphNode-TM CDP[c] + H+[c] + PEP[c] => CTP[c] + pyruvate[c] Pyruvate metabolism 72 HMR_4210 LymphNode-TM H+[c] + PEP[c] + UDP[c] => pyruvate[c] + UTP[c] Pyrimidine metabolism 73 HMR_4421 LymphNode-TM dADP[c] + H+[c] + PEP[c] => dATP[c] + pyruvate[c] Purine metabolism 74 HMR_4545 LymphNode-TM 5-hydroxy-L-tryptophan[c] + H+[c] => CO2[c] + serotonin[c] Serotonin and melatonin biosynthesis 75 HMR_4573 LymphNode-TM dGDP[c] + H+[c] + PEP[c] => dGTP[c] + pyruvate[c] Purine metabolism 76 HMR_5170 LymphNode-TM 579 ATP[c] + 13 glycyl-tRNA(gly)[c] + 580 H2O[c] + 10 L-alanyl-tRNA(ala)[c] + 4 L-arginyl-tRNA(arg)[c] + 3 L-asparaginyl-tRNA(asn)[c] + 9 L-aspartyl-tRNA(asp)[c] + 8 L-cysteinyl-tRNA(cys)[c] + 4 L-glutaminyl-tRNA(gln)[c] + 11 L-glutamyl-tRNA(glu)[c] + 3 L-histidyl-tRNA(his)[c] + 12 L-isoleucyl-tRNA(ile)[c] + 28 L-leucyl-tRNA(leu)[c] + 11 L-lysyl-tRNA(lys)[c] + 4 L-methionyl-tRNA(met)[c] + 5 L-phenylalanyl-tRNA(phe)[c] + 19 L-prolyl-tRNA(pro)[c] + 20 L-seryl-tRNA(ser)[c] + 10 L-threonyl-tRNA(thr)[c] + 3 L-tryptophanyl-tRNA(trp)[c] + 4 L-tyrosyl-tRNA(tyr)[c] + 12 L-valyl-tRNA(val)[c] => 579 ADP[c] + GM2A[c] + 767 H+[c] + 579 Pi[c] + 10 tRNA(ala)[c] + 4 tRNA(arg)[c] + 3 tRNA(asn)[c] + 9 tRNA(asp)[c] + 8 tRNA(cys)[c] + 4 tRNA(gln)[c] + 11 tRNA(glu)[c] + 13 tRNA(gly)[c] + 3 tRNA(his)[c] + 12 tRNA(ile)[c] + 28 tRNA(leu)[c] + 11 tRNA(lys)[c] + 4 tRNA(met)[c] + 5 tRNA(phe)[c] + 19 tRNA(pro)[c] + 20 tRNA(ser)[c] + 10 tRNA(thr)[c] + 3 tRNA(trp)[c] + 4 tRNA(tyr)[c] + 12 tRNA(val)[c] Protein assembly 77 HMR_5226 LymphNode-TM GM2A[c] => GM2A[l] Transport reactions 78 HMR_5286 LymphNode-TM 192 ATP[l] + GM2A[l] + 384 H2O[l] => 192 ADP[l] + 10 alanine[l] + 4 arginine[l] + 3 asparagine[l] + 9 aspartate[l] + 8 cysteine[l] + 11 glutamate[l] + 4 glutamine[l] + 13 glycine[l] + 197 H+[l] + 3 histidine[l] + 12 isoleucine[l] + 28 leucine[l] + 11 lysine[l] + 4 methionine[l] + 5 phenylalanine[l] + 192 Pi[l] + 19 proline[l] + 20 serine[l] + 10 threonine[l] + 3 tryptophan[l] + 4 tyrosine[l] + 12 valine[l] Protein degradation 79 HMR_6242 LymphNode-TM 2 Na+[s] + noradrenaline[s] => 2 Na+[c] + noradrenaline[c] Transport reactions 80 HMR_6627 LymphNode-TM dTDP[c] + H+[c] + PEP[c] <=> dTTP[c] + pyruvate[c] Pyrimidine metabolism 81 HMR_6707 LymphNode-TM H+[c] + tryptophan[c] => CO2[c] + tryptamine[c] Phenylalanine, tyrosine and tryptophan biosynthesis 82 HMR_6733 LymphNode-TM dopamine[s] + 2 Na+[s] => dopamine[c] + 2 Na+[c] Transport reactions 83 HMR_6741 LymphNode-TM ascorbate[c] + dopamine[c] + O2[c] => dehydroascorbic acid[c] + H2O[c] + noradrenaline[c] Phenylalanine, tyrosine and tryptophan biosynthesis 84 HMR_6787 LymphNode-TM H+[c] + tyrosine[c] => CO2[c] + tyramine[c] Phenylalanine, tyrosine and tryptophan biosynthesis 85 HMR_7736 LymphNode-TM ATP[c] + 3 beta-alanine[c] + H2O[c] => ADP[c] + 3 beta-alanine[s] + H+[c] + Pi[c] Transport reactions 86 HMR_7737 LymphNode-TM ATP[c] + 3 glycine[c] + H2O[c] => ADP[c] + 3 glycine[s] + H+[c] + Pi[c] Transport reactions 87 HMR_7738 LymphNode-TM 3 4-aminobutyrate[c] + ATP[c] + H2O[c] => 3 4-aminobutyrate[s] + ADP[c] + H+[c] + Pi[c] Transport reactions 88 HMR_7739 LymphNode-TM iodide[c] => iodide[s] Transport reactions 89 HMR_8515 LymphNode-TM L-lactate[s] + Na+[s] => L-lactate[c] + Na+[c] Transport reactions 90 HMR_8537 LymphNode-TM O2[c] + tetrahydrobiopterin[c] + tyrosine[c] => 4alpha-hydroxytetrahydrobiopterin[c] + L-dopa[c] Tyrosine metabolism 91 HMR_9037 LymphNode-TM phytanic acid[s] <=> phytanic acid[x] Exchange/demand reactions 92 HMR_9142 LymphNode-TM nicotinate[s] <=> nicotinate[x] Exchange/demand reactions 93 HMR_9614 LymphNode-TM dopamine[s] + Na+[s] => dopamine[c] + Na+[c] Transport reactions 94 HMR_9615 LymphNode-TM Na+[s] + noradrenaline[s] => Na+[c] + noradrenaline[c] Transport reactions 95 HXCOAtx LymphNode-TM hexanoyl-CoA[p] <=> hexanoyl-CoA[c] Transport reactions 96 IBUP_Rtdhep LymphNode-TM urate[c] + ibuprofen-R[s] <=> urate[s] + ibuprofen-R[c] Drug metabolism 97 ILESERARGr LymphNode-TM 2 H2O[c] + Isolecyl-Seryl-Arginine[c] <=> arginine[c] + isoleucine[c] + serine[c] Peptide metabolism 98 LYSVALTRPr LymphNode-TM 2 H2O[c] + Lysyl-Valyl-Tryptophan[c] <=> lysine[c] + tryptophan[c] + valine[c] Peptide metabolism 99 METGLNTYRr LymphNode-TM 2 H2O[c] + Methionyl-Glutaminyl-Tyrosine[c] <=> glutamine[c] + methionine[c] + tyrosine[c] Peptide metabolism 100 NACSMCTte LymphNode-TM Na+[s] + nicotinate[s] <=> Na+[c] + nicotinate[c] Transport reactions 101 NFDACitr LymphNode-TM acid metabolite of nifedipine[r] <=> acid metabolite of nifedipine[c] Drug metabolism 102 NFDACtep LymphNode-TM acid metabolite of nifedipine[c] <=> acid metabolite of nifedipine[s] Drug metabolism 103 PPASMCT1 LymphNode-TM Na+[s] + propanoate[s] <=> Na+[c] + propanoate[c] Transport reactions 104 PYRSMCT1 LymphNode-TM Na+[s] + pyruvate[s] <=> Na+[c] + pyruvate[c] Transport reactions 105 4OHPROIMINOtc Skin-TM chloride[s] + 2 Na+[s] + trans-4-hydroxy-L-proline[s] => chloride[c] + 2 Na+[c] + trans-4-hydroxy-L-proline[c] Transport reactions 106 C10CRNtr Skin-TM Decanoyl Carnitine[s] <=> Decanoyl Carnitine[c] Transport reactions 107 EX_c10crn[e] Skin-TM Decanoyl Carnitine[s] <=> Decanoyl Carnitine[x] Exchange/demand reactions 108 HMR_0640 Skin-TM acetyl-CoA[c] + choline[c] => acetylcholine[c] + CoA[c] Glycerophospholipid metabolism 109 HMR_10127 Skin-TM 2 Na+[s] + tauro-hyodeoxycholic acid[s] => 2 Na+[c] + tauro-hyodeoxycholic acid[c] Transport reactions 110 HMR_3851 Skin-TM 3-sulfinylpyruvic acid[c] + H2O[c] => H+[c] + pyruvate[c] + sulfite[c] Sulfur metabolism 111 HMR_4249 Skin-TM xanthurenate[c] <=> xanthurenate[s] Transport reactions 112 HMR_4545 Skin-TM 5-hydroxy-L-tryptophan[c] + H+[c] => CO2[c] + serotonin[c] Serotonin and melatonin biosynthesis 113 HMR_6617 Skin-TM thioredoxin[c] <=> thioredoxin[n] Transport reactions 114 HMR_6653 Skin-TM 9-cis-retinal[c] + H+[c] + NADPH[c] + O2[c] => 4-OH-9-cis-retinal[c] + H2O[c] + NADP+[c] Retinol metabolism 115 HMR_6707 Skin-TM H+[c] + tryptophan[c] => CO2[c] + tryptamine[c] Phenylalanine, tyrosine and tryptophan biosynthesis 116 HMR_6728 Skin-TM O2[c] + tetrahydrobiopterin[c] + tyrosine[c] => dihydrobiopterin[c] + H2O[c] + L-dopa[c] Phenylalanine, tyrosine and tryptophan biosynthesis 117 HMR_6787 Skin-TM H+[c] + tyrosine[c] => CO2[c] + tyramine[c] Phenylalanine, tyrosine and tryptophan biosynthesis 118 HMR_8537 Skin-TM O2[c] + tetrahydrobiopterin[c] + tyrosine[c] => 4alpha-hydroxytetrahydrobiopterin[c] + L-dopa[c] Tyrosine metabolism 119 HMR_9693 Skin-TM xanthurenate[s] <=> xanthurenate[x] Exchange/demand reactions 120 HMR_9780 Skin-TM linolenate[l] => linolenate[c] Transport reactions 121 ILETRPTYRr Skin-TM 2 H2O[c] + Isolecyl-Tryptophanyl-Tyrosine[c] <=> isoleucine[c] + tryptophan[c] + tyrosine[c] Peptide metabolism 122 METTRPPHEr Skin-TM 2 H2O[c] + Methionyl-Tryptophanyl-Phenylalanine[c] <=> methionine[c] + phenylalanine[c] + tryptophan[c] Peptide metabolism 123 PROIMINOtc Skin-TM chloride[s] + 2 Na+[s] + proline[s] => chloride[c] + 2 Na+[c] + proline[c] Transport reactions 124 PROTEIN_BS Skin-TM 0.6 alanine[c] + 0.377 arginine[c] + 0.2881 asparagine[c] + 0.359 aspartate[c] + 0.145 cysteine[c] + 0.386 glutamate[c] + 0.322 glutamine[c] + 0.538 glycine[c] + 0.143 histidine[c] + 0.324 isoleucine[c] + 0.564 leucine[c] + 0.57 lysine[c] + 0.138 methionine[c] + 0.219 phenylalanine[c] + 0.313 proline[c] + 0.43 serine[c] + 0.386 threonine[c] + 0.044 tryptophan[c] + 0.182 tyrosine[c] + 0.416 valine[c] => [protein][c] Protein assembly 125 4HATVLAChc Brain-TM ATP[c] + 4-hydroxy-atorvastatin-acid / para-hydroxy-atorvastatin acid[c] => AMP[c] + PPi[c] + 4-hydroxy-atorvastatin-lactone / para-hydroxy-atorvastatin lactone[c] Drug metabolism 126 4OHPROIMINOtc Brain-TM chloride[s] + 2 Na+[s] + trans-4-hydroxy-L-proline[s] => chloride[c] + 2 Na+[c] + trans-4-hydroxy-L-proline[c] Transport reactions 127 ASPHISCYSr Brain-TM 2 H2O[c] + Aspartyl-Histidyl-Cysteine[c] <=> aspartate[c] + cysteine[c] + histidine[c] Peptide metabolism 128 ASPMETASPr Brain-TM 2 H2O[c] + Aspartyl-Methionyl-Aspartate[c] <=> 2 aspartate[c] + methionine[c] Peptide metabolism 129 C06315t Brain-TM H+[c] + lipoxin B4[c] <=> H+[s] + lipoxin B4[s] Transport reactions 130 CDCA3GSr Brain-TM UDP-glucuronate[r] + Chenodeoxycholate[r] => UDP[r] + Chenodeoxycholic acid-3glucuronide, CDCA-3G[r] Bile acid biosynthesis 131 CDCA3Gtr Brain-TM Chenodeoxycholic acid-3glucuronide, CDCA-3G[c] <=> Chenodeoxycholic acid-3glucuronide, CDCA-3G[r] Transport reactions 132 DCA24GSr Brain-TM 3alpha,12alpha-dihydroxy-5beta-cholanate[r] + UDP-glucuronate[r] => UDP[r] + Deoxycholic acid-24glucuronide, CDA-24G[r] Bile acid biosynthesis 133 DCA3GSr Brain-TM 3alpha,12alpha-dihydroxy-5beta-cholanate[r] + UDP-glucuronate[r] => UDP[r] + Deoxycholic acid-3glucuronide, CDA-3G[r] Bile acid biosynthesis 134 DCMPtr Brain-TM dCMP[s] <=> dCMP[c] Transport reactions 135 EX_C06315[e] Brain-TM lipoxin B4[s] <=> lipoxin B4[x] Exchange/demand reactions 136 EX_HC00002[e] Brain-TM antichymotrypsin[s] <=> antichymotrypsin[x] Exchange/demand reactions 137 EX_dcmp[e] Brain-TM dCMP[s] <=> dCMP[x] Exchange/demand reactions 138 HMR_1592 Brain-TM 7alpha,12alpha-dihydroxycholest-4-en-3-one[r] + ATP[r] + H2O[r] => 7alpha,12alpha-dihydroxycholest-4-en-3-one[c] + ADP[r] + H+[r] + Pi[r] Transport reactions 139 HMR_4905 Brain-TM ATP[c] + Pi[m] => ATP[m] + Pi[c] Transport reactions 140 HMR_5200 Brain-TM antichymotrypsin[c] <=> antichymotrypsin[s] Transport reactions 141 HMR_5253 Brain-TM PS-LD pool[l] => PS-LD pool[r] Transport reactions 142 HMR_5260 Brain-TM antichymotrypsin[c] + 422 ATP[c] + 844 H2O[c] => 422 ADP[c] + 34 alanine[c] + 16 arginine[c] + 19 asparagine[c] + 25 aspartate[c] + 3 cysteine[c] + 29 glutamate[c] + 17 glutamine[c] + 16 glycine[c] + 434 H+[c] + 9 histidine[c] + 20 isoleucine[c] + 59 leucine[c] + 26 lysine[c] + 14 methionine[c] + 25 phenylalanine[c] + 422 Pi[c] + 16 proline[c] + 30 serine[c] + 29 threonine[c] + 3 tryptophan[c] + 9 tyrosine[c] + 24 valine[c] Protein degradation 143 HMR_6617 Brain-TM thioredoxin[c] <=> thioredoxin[n] Transport reactions 144 HMR_6619 Brain-TM oxidized thioredoxin[c] <=> oxidized thioredoxin[n] Transport reactions 145 HMR_6622 Brain-TM thioredoxin[n] + UTP[n] => dUTP[n] + H2O[n] + oxidized thioredoxin[n] Pyrimidine metabolism 146 HMR_6989 Brain-TM iodide[s] + Na+[s] => iodide[c] + Na+[c] Transport reactions 147 HMR_8062 Brain-TM dehydroalanine[c] + NADPH[c] + PAPS[c] => L-cysteate[c] + NADP+[c] + PAP[c] Cysteine and methionine metabolism 148 HMR_8533 Brain-TM 2 2-carboxy-2,3-dihydro-5,6-dihydroxyindole[c] + O2[c] => 2 H2O[c] + 2 L-dopachrome[c] Tyrosine metabolism 149 HMR_8924 Brain-TM iodide[s] + 2 Na+[s] => iodide[c] + 2 Na+[c] Transport reactions 150 PROIMINOtc Brain-TM chloride[s] + 2 Na+[s] + proline[s] => chloride[c] + 2 Na+[c] + proline[c] Transport reactions 151 PROLYSPROr Brain-TM 2 H2O[c] + Prolyl-Lysyl-Proline[c] <=> lysine[c] + 2 proline[c] Peptide metabolism 152 r0994 Brain-TM Chenodeoxycholate[c] <=> Chenodeoxycholate[r] Transport reactions 153 r1078 Brain-TM tyrosine[c] => tyrosine[m] Transport reactions