rxns type rxnEq subSys 1 ALLOP2tu AdrenalGland-TM H+[s] + allopurinol[s] => H+[c] + allopurinol[c] Drug metabolism 2 HMR_0921 AdrenalGland-TM ceramide pool[r] + UDP-galactose[r] => D-galactosyl-N-acylsphingosine[r] + H+[r] + UDP[r] Glycosphingolipid metabolism 3 HMR_1573 AdrenalGland-TM acetoacetyl-CoA[m] + acetyl-CoA[m] + H2O[m] => CoA[m] + H+[m] + HMG-CoA[m] Terpenoid backbone biosynthesis 4 HMR_4519 AdrenalGland-TM H2O[c] + hypoxanthine[c] + NAD+[c] => H+[c] + NADH[c] + xanthine[c] Purine metabolism 5 HMR_4520 AdrenalGland-TM H2O[c] + hypoxanthine[c] + O2[c] => H2O2[c] + xanthine[c] Purine metabolism 6 HMR_4646 AdrenalGland-TM H2O[c] + NAD+[c] + xanthine[c] => H+[c] + NADH[c] + urate[c] Purine metabolism 7 HMR_4649 AdrenalGland-TM H2O[c] + O2[c] + xanthine[c] => H2O2[c] + urate[c] Purine metabolism 8 HMR_5391 AdrenalGland-TM 4-methylthio-2-oxobutanoic acid[c] + glutamate[c] => AKG[c] + methionine[c] Cysteine and methionine metabolism 9 HMR_7172 AdrenalGland-TM CMP-N-acetylneuraminate[g] + sialyl-T antigen[g] => CMP[g] + disialyl-T antigen[g] + H+[g] O-glycan metabolism 10 HMR_7183 AdrenalGland-TM CMP-N-acetylneuraminate[g] + Tn-antigen[g] => CMP[g] + H+[g] + sialyl-Tn antigen[g] O-glycan metabolism 11 HMR_7622 AdrenalGland-TM [protein]-L-arginine[c] + H2O[c] => [protein]-L-citrulline[c] + NH4+[c] Protein modification 12 HMR_8147 AdrenalGland-TM glucosylceramide pool[g] + UDP-galactose[g] => H+[g] + LacCer pool[g] + UDP[g] Sphingolipid metabolism 13 HMR_8151 AdrenalGland-TM galactosylgloboside[g] + UDP-N-acetylglucosamine[g] => glcnac-gal-globoside[g] + H+[g] + UDP[g] Sphingolipid metabolism 14 HMR_8152 AdrenalGland-TM glcnac-gal-globoside[g] + UDP-galactose[g] => gal-glcnac-gal-globoside[g] + H+[g] + UDP[g] Sphingolipid metabolism 15 HMR_8249 AdrenalGland-TM globotriaosylceramide[g] + UDP-galactose[g] => galthcrm heparan sulfate[g] + H+[g] + UDP[g] Sphingolipid metabolism 16 HMR_8250 AdrenalGland-TM galthcrm heparan sulfate[g] + UDP-galactose[g] => galgalthcrm heparan sulfate[g] + H+[g] + UDP[g] Sphingolipid metabolism 17 HMR_8251 AdrenalGland-TM galgalthcrm heparan sulfate[g] + UDP-galactose[g] => galgalgalthcrm heparan sulfate[g] + H+[g] + UDP[g] Sphingolipid metabolism 18 HMR_8279 AdrenalGland-TM nLc5Cer[g] + UDP-galactose[g] => H+[g] + nLc6Cer[c] + UDP[g] Blood group biosynthesis 19 RE3434R AdrenalGland-TM H+[r] + NADPH[r] + O2[r] + 10,11-dihydro-12-epi-LTB4[r] => 20-OH-10,11-dihydro-LTB4[r] + H2O[r] + NADP+[r] Eicosanoid metabolism 20 HMR_0920 Liver-TM ceramide pool[g] + UDP-galactose[g] => D-galactosyl-N-acylsphingosine[g] + H+[g] + UDP[g] Glycosphingolipid metabolism 21 HMR_7800 Liver-TM ADP[c] + GDP[c] <=> AMP[c] + GTP[c] Nucleotide metabolism 22 HMR_7802 Liver-TM 2 dADP[c] <=> dAMP[c] + dATP[c] Nucleotide metabolism 23 HMR_8461 Liver-TM dCDP[c] + GDP[c] <=> dCMP[c] + GTP[c] Nucleotide metabolism 24 HMR_7223 Lung-TM heparan sulfate proteoglycan[g] => heparan sulfate proteoglycan[s] Transport reactions 25 HMR_7800 Lung-TM ADP[c] + GDP[c] <=> AMP[c] + GTP[c] Nucleotide metabolism 26 HMR_7802 Lung-TM 2 dADP[c] <=> dAMP[c] + dATP[c] Nucleotide metabolism 27 HMR_8461 Lung-TM dCDP[c] + GDP[c] <=> dCMP[c] + GTP[c] Nucleotide metabolism 28 12DHCHOLt2 LymphNode-TM 2 Na+[s] + 12-Dehydrocholic acid; 12-Oxodeoxycholic acid; 12oxo-3alpha,7alpha-Dihydroxy-5beta-cholan-24-oic acid[s] => 2 Na+[c] + 12-Dehydrocholic acid; 12-Oxodeoxycholic acid; 12oxo-3alpha,7alpha-Dihydroxy-5beta-cholan-24-oic acid[c] Transport reactions 29 2HATVACIDhc LymphNode-TM H2O[c] + 2-hydroxy-atorvastatin-lactone / ortho-hydroxy-atorvastatin lactone[c] => H+[c] + 2-hydroxy-atorvastatin-acid / ortho-hydroxy-atorvastatin acid[c] Drug metabolism 30 3HLVSTAChep LymphNode-TM H2O[c] + 3''-hydroxy-lovastatin lactone form[c] => H+[c] + 3''-hydroxy-lovastatin acid form[c] Drug metabolism 31 3HLVSTitr LymphNode-TM 3''-hydroxy-lovastatin lactone form[r] <=> 3''-hydroxy-lovastatin lactone form[c] Drug metabolism 32 3HSMVACIDhep LymphNode-TM H2O[c] + 3'-hydroxy-simvastatin-lactone form[c] => H+[c] + 3'-hydroxy-simvastatin-acid form[c] Drug metabolism 33 3HSMVitr LymphNode-TM 3'-hydroxy-simvastatin-lactone form[r] <=> 3'-hydroxy-simvastatin-lactone form[c] Drug metabolism 34 4HATVACIDhc LymphNode-TM H2O[c] + 4-hydroxy-atorvastatin-lactone / para-hydroxy-atorvastatin lactone[c] => H+[c] + 4-hydroxy-atorvastatin-acid / para-hydroxy-atorvastatin acid[c] Drug metabolism 35 4HATVLACitr LymphNode-TM 4-hydroxy-atorvastatin-lactone / para-hydroxy-atorvastatin lactone[r] <=> 4-hydroxy-atorvastatin-lactone / para-hydroxy-atorvastatin lactone[c] Drug metabolism 36 6CSMVACIDhep LymphNode-TM H2O[c] + 6'-beta-carboxy-simvastatin-lactone form[c] => H+[c] + 6'-beta-carboxy-simvastatin-acid form[c] Drug metabolism 37 6CSMVitr LymphNode-TM 6'-beta-carboxy-simvastatin-lactone form[c] <=> 6'-beta-carboxy-simvastatin-lactone form[r] Drug metabolism 38 6HLVSTAChep LymphNode-TM H2O[c] + 6'-beta-hydroxy-lovastatin lactone form[c] => H+[c] + 6'-beta-hydroxy-lovastatin-acid form[c] Drug metabolism 39 6HLVSTitr LymphNode-TM 6'-beta-hydroxy-lovastatin lactone form[r] <=> 6'-beta-hydroxy-lovastatin lactone form[c] Drug metabolism 40 6HMSMVACIDhep LymphNode-TM H2O[c] + 6'-beta-hydroxy-methyl-simvastatin-lactone form[c] => H+[c] + 6'-beta-hydroxy-methyl-simvastatin-acid form[c] Drug metabolism 41 6HMSMVitr LymphNode-TM 6'-beta-hydroxy-methyl-simvastatin-lactone form[c] <=> 6'-beta-hydroxy-methyl-simvastatin-lactone form[r] Drug metabolism 42 6HSMVACIDhep LymphNode-TM H2O[c] + 6'-beta-hydroxy simvastatin lactone[c] => H+[c] + 6'-beta-hydroxy simvastatin acid[c] Drug metabolism 43 6HSMVitr LymphNode-TM 6'-beta-hydroxy simvastatin lactone[r] <=> 6'-beta-hydroxy simvastatin lactone[c] Drug metabolism 44 6MELACAChep LymphNode-TM H2O[c] + 6'-exomethylene-lovastatin lactone form[c] => H+[c] + 6'-exomethylene-lovastatin-acid form[c] Drug metabolism 45 6MELVSTitr LymphNode-TM 6'-exomethylene-lovastatin lactone form[r] <=> 6'-exomethylene-lovastatin lactone form[c] Drug metabolism 46 7DHCDCHOLt2 LymphNode-TM 2 Na+[s] + 7-Dehydrochenodeoxycholic acid; 7oxo-3alpha-hydroxy-5beta-cholan-24-oic acid[s] => 2 Na+[c] + 7-Dehydrochenodeoxycholic acid; 7oxo-3alpha-hydroxy-5beta-cholan-24-oic acid[c] Transport reactions 47 7DHCHOLt2 LymphNode-TM 2 Na+[s] + 7-Dehydrocholic acid; 7-Oxodeoxycholic acid; 7oxo-3alpha,12alpha-Dihydroxy-5beta-cholan-24-oic acid[s] => 2 Na+[c] + 7-Dehydrocholic acid; 7-Oxodeoxycholic acid; 7oxo-3alpha,12alpha-Dihydroxy-5beta-cholan-24-oic acid[c] Transport reactions 48 ATVACIDhc LymphNode-TM H2O[c] + atorvastatin-lactone[c] => H+[c] + atorvastatin-acid[c] Drug metabolism 49 C05769te LymphNode-TM ATP[c] + coproporphyrin I[c] + H2O[c] => ADP[c] + coproporphyrin I[s] + H+[c] + Pi[c] Transport reactions 50 COPROSTt2 LymphNode-TM 2 Na+[s] + Coprostanol[s] => 2 Na+[c] + Coprostanol[c] Transport reactions 51 DACT LymphNode-TM 2,3-Dihydro-1H-Indole-5,6-Dione[c] <=> dopaminochrome[c] Tyrosine metabolism 52 EX_CE2915[e] LymphNode-TM beta-casomorphin[s] <=> beta-casomorphin[x] Exchange/demand reactions 53 EX_CE2916[e] LymphNode-TM neocasomorphin[s] <=> neocasomorphin[x] Exchange/demand reactions 54 EX_CE2917[e] LymphNode-TM apelin-13[s] <=> apelin-13[x] Exchange/demand reactions 55 EX_CE4722[e] LymphNode-TM beta-casomorphin (1-6)[s] <=> beta-casomorphin (1-6)[x] Exchange/demand reactions 56 EX_CE4723[e] LymphNode-TM neocasomorphin (1-5)[s] <=> neocasomorphin (1-5)[x] Exchange/demand reactions 57 EX_CE4724[e] LymphNode-TM apelin-(1-12)[s] <=> apelin-(1-12)[x] Exchange/demand reactions 58 EX_rsvlac[e] LymphNode-TM rosuvastatin-5S-lactone[s] <=> rosuvastatin-5S-lactone[x] Exchange/demand reactions 59 FACOAL40im LymphNode-TM ATP[m] + CoA[m] + butyrate[m] => AMP[m] + butyryl-CoA[m] + PPi[m] Fatty acid oxidation 60 HMR_0867 LymphNode-TM IV2Fuc-Lc4Cer[c] + UDP-N-acetyl-D-galactosamine[c] => H+[c] + type I A glycolipid[c] + UDP[c] Glycosphingolipid biosynthesis-lacto and neolacto series 61 HMR_0868 LymphNode-TM IV2Fuc-Lc4Cer[c] + UDP-galactose[c] => H+[c] + type I B glycolipid[c] + UDP[c] Glycosphingolipid biosynthesis-lacto and neolacto series 62 HMR_0887 LymphNode-TM type III H glycolipid[c] + UDP-N-acetyl-D-galactosamine[c] => H+[c] + type III A glycolipid[c] + UDP[c] Glycosphingolipid biosynthesis-lacto and neolacto series 63 HMR_0901 LymphNode-TM UDP-galactose[c] + VI2Fuc-nLc6[c] => G00083[c] + H+[c] + UDP[c] Glycosphingolipid biosynthesis-lacto and neolacto series 64 HMR_0905 LymphNode-TM G00074[c] + UDP-N-acetyl-D-galactosamine[c] => H+[c] + type IIIAb[c] + UDP[c] Glycosphingolipid biosynthesis-lacto and neolacto series 65 HMR_10036 LymphNode-TM acyl-CoA pool[c] <=> 0.0004 (10Z)-heptadecenoyl-CoA[c] + 0.0004 (11Z)-docosenoyl-CoA[c] + 0.0004 (11Z)-eicosenoyl-CoA[c] + 0.0004 (11Z,14Z)-eicosadienoyl-CoA[c] + 0.0004 (11Z,14Z,17Z)-eicosatrienoyl-CoA[c] + 0.0004 (13Z)-docosenoyl-CoA[c] + 0.0004 (13Z)-eicosenoyl-CoA[c] + 0.0004 (13Z)-octadecenoyl-CoA[c] + 0.0004 (13Z,16Z)-docosadienoyl-CoA[c] + 0.0004 (15Z)-tetracosenoyl-CoA[c] + 0.0038 (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA[c] + 0.0278 (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA[c] + 0.0004 (5Z,8Z,11Z)-eicosatrienoyl-CoA[c] + 0.0116 (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA[c] + 0.0004 (6Z,9Z)-octadecadienoyl-CoA[c] + 0.0025 (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA[c] + 0.0004 (6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA[c] + 0.0004 (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA[c] + 0.0004 (7Z)-octadecenoyl-CoA[c] + 0.0004 (7Z)-tetradecenoyl-CoA[c] + 0.0014 (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA[c] + 0.0059 (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA[c] + 0.0004 (8Z,11Z)-eicosadienoyl-CoA[c] + 0.0115 (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA[c] + 0.0004 (9E)-octadecenoyl-CoA[c] + 0.0004 (9E)-tetradecenoyl-CoA[c] + 0.0004 (9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA[c] + 0.0004 (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA[c] + 0.0004 10,13,16,19-docosatetraenoyl-CoA[c] + 0.0004 10,13,16-docosatrienoyl-CoA[c] + 0.0004 12,15,18,21-tetracosatetraenoyl-CoA[c] + 0.0004 13,16,19-docosatrienoyl-CoA[c] + 0.0004 5-tetradecenoyl-CoA[c] + 0.0004 7-hexadecenoyl-CoA[c] + 0.0004 9-eicosenoyl-CoA[c] + 0.0004 9-heptadecenoyl-CoA[c] + 0.1083 arachidonyl-CoA[c] + 0.025 cis-vaccenoyl-CoA[c] + 0.0215 dihomo-gamma-linolenoyl-CoA[c] + 0.0004 docosanoyl-CoA[c] + 0.0004 eicosanoyl-CoA[c] + 0.0029 gamma-linolenoyl-CoA[c] + 0.0004 heneicosanoyl-CoA[c] + 0.0004 heptadecanoyl-CoA[c] + 0.0004 hexacosanoyl-CoA[c] + 0.0004 hexacosenoyl-CoA[c] + 0.0004 lauroyl-CoA[c] + 0.0084 linolenoyl-CoA[c] + 0.1915 linoleoyl-CoA[c] + 0.0133 myristoyl-CoA[c] + 0.0004 nonadecanoyl-CoA[c] + 0.1545 oleoyl-CoA[c] + 0.0219 palmitoleoyl-CoA[c] + 0.222 palmitoyl-CoA[c] + 0.0004 pentadecanoyl-CoA[c] + 0.1498 stearoyl-CoA[c] + 0.0004 tetracosanoyl-CoA[c] + 0.0004 tricosanoyl-CoA[c] + 0.0004 tridecanoyl-CoA[c] Pool reactions 66 HMR_1536 LymphNode-TM 24,25-dihydrolanosterol[c] + H+[c] + NADPH[c] + O2[c] => 4,4-dimethyl-14alpha-hydroxymethyl-5alpha-cholesta-8-en-3beta-ol[c] + H2O[c] + NADP+[c] Cholesterol biosynthesis 3 (Kandustch-Russell pathway) 67 HMR_1538 LymphNode-TM 4,4-dimethyl-14alpha-hydroxymethyl-5alpha-cholesta-8-en-3beta-ol[c] + H+[c] + NADPH[c] + O2[c] => 4,4-dimethyl-14alpha-formyl-5alpha-cholesta-8-en-3beta-ol[c] + 2 H2O[c] + NADP+[c] Cholesterol biosynthesis 3 (Kandustch-Russell pathway) 68 HMR_1539 LymphNode-TM 4,4-dimethyl-14alpha-formyl-5alpha-cholesta-8-en-3beta-ol[c] + NADPH[c] + O2[c] => 4,4-dimethyl-5alpha-cholesta-8,14-dien-3-beta-ol[c] + formate[c] + H2O[c] + NADP+[c] Cholesterol biosynthesis 3 (Kandustch-Russell pathway) 69 HMR_1540 LymphNode-TM 4,4-dimethyl-5alpha-cholesta-8,14-dien-3-beta-ol[c] + H+[c] + NADPH[c] => 4,4-dimethyl-5alpha-cholesta-8-en-3-beta-ol[c] + NADP+[c] Cholesterol biosynthesis 3 (Kandustch-Russell pathway) 70 HMR_1573 LymphNode-TM acetoacetyl-CoA[m] + acetyl-CoA[m] + H2O[m] => CoA[m] + H+[m] + HMG-CoA[m] Terpenoid backbone biosynthesis 71 HMR_3873 LymphNode-TM 2 ATP[m] + CO2[m] + H2O[m] + NH3[m] => 2 ADP[m] + carbamoyl-phosphate[m] + 2 H+[m] + Pi[m] Alanine, aspartate and glutamate metabolism 72 HMR_4498 LymphNode-TM [ACP][c] + H2O[c] => apo-[ACP][c] + H+[c] + phosphopantetheine[c] Pantothenate and CoA biosynthesis 73 HMR_4596 LymphNode-TM 2-oxoadipate[c] + glutamate[c] <=> AKG[c] + L-2-aminoadipate[c] Lysine metabolism 74 HMR_5152 LymphNode-TM 1269 ATP[c] + 16 glycyl-tRNA(gly)[c] + 1270 H2O[c] + 34 L-alanyl-tRNA(ala)[c] + 16 L-arginyl-tRNA(arg)[c] + 19 L-asparaginyl-tRNA(asn)[c] + 25 L-aspartyl-tRNA(asp)[c] + 3 L-cysteinyl-tRNA(cys)[c] + 17 L-glutaminyl-tRNA(gln)[c] + 29 L-glutamyl-tRNA(glu)[c] + 9 L-histidyl-tRNA(his)[c] + 20 L-isoleucyl-tRNA(ile)[c] + 59 L-leucyl-tRNA(leu)[c] + 26 L-lysyl-tRNA(lys)[c] + 14 L-methionyl-tRNA(met)[c] + 25 L-phenylalanyl-tRNA(phe)[c] + 16 L-prolyl-tRNA(pro)[c] + 30 L-seryl-tRNA(ser)[c] + 29 L-threonyl-tRNA(thr)[c] + 3 L-tryptophanyl-tRNA(trp)[c] + 9 L-tyrosyl-tRNA(tyr)[c] + 24 L-valyl-tRNA(val)[c] => 1269 ADP[c] + antichymotrypsin[c] + 1680 H+[c] + 1269 Pi[c] + 34 tRNA(ala)[c] + 16 tRNA(arg)[c] + 19 tRNA(asn)[c] + 25 tRNA(asp)[c] + 3 tRNA(cys)[c] + 17 tRNA(gln)[c] + 29 tRNA(glu)[c] + 16 tRNA(gly)[c] + 9 tRNA(his)[c] + 20 tRNA(ile)[c] + 59 tRNA(leu)[c] + 26 tRNA(lys)[c] + 14 tRNA(met)[c] + 25 tRNA(phe)[c] + 16 tRNA(pro)[c] + 30 tRNA(ser)[c] + 29 tRNA(thr)[c] + 3 tRNA(trp)[c] + 9 tRNA(tyr)[c] + 24 tRNA(val)[c] Protein assembly 75 HMR_5288 LymphNode-TM 349 ATP[c] + glycogenin[c] + 698 H2O[c] => 349 ADP[c] + 22 alanine[c] + 12 arginine[c] + 12 asparagine[c] + 26 aspartate[c] + 6 cysteine[c] + 15 glutamate[c] + 14 glutamine[c] + 18 glycine[c] + 360 H+[c] + 9 histidine[c] + 12 isoleucine[c] + 39 leucine[c] + 18 lysine[c] + 8 methionine[c] + 20 phenylalanine[c] + 349 Pi[c] + 15 proline[c] + 31 serine[c] + 25 threonine[c] + 7 tryptophan[c] + 13 tyrosine[c] + 28 valine[c] Protein degradation 76 HMR_6673 LymphNode-TM 13-cis-retinal[r] <=> retinal[r] Retinol metabolism 77 HMR_7223 LymphNode-TM heparan sulfate proteoglycan[g] => heparan sulfate proteoglycan[s] Transport reactions 78 HMR_7858 LymphNode-TM dUDP[c] <=> dUDP[n] Transport reactions 79 HMR_8193 LymphNode-TM N-acetylgalactosamine[c] <=> N-acetylgalactosamine[g] Transport reactions 80 HMR_8194 LymphNode-TM globoside[g] + N-acetylgalactosamine[g] => beta-GalNAc-globoside[g] + H2O[g] Sphingolipid metabolism 81 HMR_8263 LymphNode-TM type I H glycolipid[g] + UDP-N-acetyl-D-galactosamine[g] => H+[g] + type I A glycolipid[g] + UDP[g] Blood group biosynthesis 82 HMR_8267 LymphNode-TM type I H glycolipid[g] + UDP-galactose[g] => H+[g] + type I B glycolipid[g] + UDP[g] Blood group biosynthesis 83 HMR_8281 LymphNode-TM type II H glycolipid[g] + UDP-galactose[g] => galfuc12gal14acglcgalgluside heparan sulfate[g] + H+[g] + UDP[g] Blood group biosynthesis 84 HMR_8288 LymphNode-TM type III H glycolipid[g] + UDP-N-acetyl-D-galactosamine[g] => H+[g] + type III A glycolipid[g] + UDP[g] Blood group biosynthesis 85 HMR_8295 LymphNode-TM fucgalacgalfucgalacglcgal14acglcgalgluside heparan sulfate[g] + UDP-N-acetyl-D-galactosamine[g] => H+[g] + type IIIAb[g] + UDP[g] Blood group biosynthesis 86 HMR_8298 LymphNode-TM UDP-galactose[g] + VI2Fuc-nLc6[g] => galfucgalacglcgal14acglcgalgluside heparan sulfate[g] + H+[g] + UDP[g] Blood group biosynthesis 87 HMR_8302 LymphNode-TM fucfucgalacglcgalacglcgal14acglcgalgluside heparan sulfate[g] + 2 UDP-galactose[g] => galgalfucfucgalacglcgalacglcgal14acglcgalgluside heparan sulfate[g] + 2 H+[g] + 2 UDP[g] Blood group biosynthesis 88 HMR_8654 LymphNode-TM 2 ATP[m] + HCO3-[m] + NH3[m] => 2 ADP[m] + carbamoyl-phosphate[m] + H+[m] + Pi[m] Alanine, aspartate and glutamate metabolism 89 HMR_9613 LymphNode-TM 4-aminobutyrate[s] + chloride[s] + 2 Na+[s] => 4-aminobutyrate[c] + chloride[c] + 2 Na+[c] Transport reactions 90 HMR_9649 LymphNode-TM coproporphyrin I[c] <=> coproporphyrin I[s] Transport reactions 91 HMR_9701 LymphNode-TM coproporphyrin I[s] <=> coproporphyrin I[x] Exchange/demand reactions 92 ICDCHOLt2 LymphNode-TM 2 Na+[s] + Isochenodeoxycholic acid; 3beta,7alpha-Dihydroxy-5beta-cholanic acid[s] => 2 Na+[c] + Isochenodeoxycholic acid; 3beta,7alpha-Dihydroxy-5beta-cholanic acid[c] Transport reactions 93 ISOCHOLt2 LymphNode-TM 2 Na+[s] + Isochenodeoxycholic acid; 3beta,7alpha,12alpha-Trihydroxy-5beta-cholanic acid[s] => 2 Na+[c] + Isochenodeoxycholic acid; 3beta,7alpha,12alpha-Trihydroxy-5beta-cholanic acid[c] Transport reactions 94 NH4t3r LymphNode-TM H+[s] + NH4+[c] <=> H+[c] + NH4+[s] Transport reactions 95 RE0936E LymphNode-TM H2O[s] + beta-casomorphin[s] <=> isoleucine[s] + beta-casomorphin (1-6)[s] Miscellaneous 96 RE0937E LymphNode-TM H2O[s] + neocasomorphin[s] <=> isoleucine[s] + neocasomorphin (1-5)[s] Miscellaneous 97 RE0938E LymphNode-TM H2O[s] + apelin-13[s] <=> phenylalanine[s] + apelin-(1-12)[s] Miscellaneous 98 RSVGLUChc LymphNode-TM 2 UDP-glucuronate[r] + rosuvastatin[r] => 2 UDP[r] + rosuvastatin-glucuronide[r] Drug metabolism 99 RSVLAChv LymphNode-TM rosuvastatin-glucuronide[r] => 2 glucuronate[r] + rosuvastatin-5S-lactone[r] Drug metabolism 100 RSVLACitr LymphNode-TM rosuvastatin-5S-lactone[c] <=> rosuvastatin-5S-lactone[r] Drug metabolism 101 RSVLACteb LymphNode-TM ATP[c] + H2O[c] + rosuvastatin-5S-lactone[c] => ADP[c] + H+[c] + Pi[c] + rosuvastatin-5S-lactone[s] Drug metabolism 102 RSVSPONhc LymphNode-TM 2 H2O[c] + rosuvastatin-5S-lactone[c] => 2 H+[c] + rosuvastatin[c] Drug metabolism 103 RSVitr LymphNode-TM rosuvastatin[c] <=> rosuvastatin[r] Drug metabolism 104 SMVHYDROhep LymphNode-TM H2O[c] + simvastatin lactone form[c] => H+[c] + simvastatin dihydroxy acid form[c] Drug metabolism 105 UCHOLt2 LymphNode-TM 2 Na+[s] + Ursocholic acid; 3alpha,7beta,12alpha-Trihydroxy-5beta-cholan-24-oic acid; 3alpha,7beta,12alpha-Trihydroxy-5beta-cholanic acid; 7beta-Hydroxyisocholic acid; 7-Epicholic acid[s] => 2 Na+[c] + Ursocholic acid; 3alpha,7beta,12alpha-Trihydroxy-5beta-cholan-24-oic acid; 3alpha,7beta,12alpha-Trihydroxy-5beta-cholanic acid; 7beta-Hydroxyisocholic acid; 7-Epicholic acid[c] Transport reactions 106 r0034 LymphNode-TM 2 ATP[m] + CO2[m] + H2O[m] + NH4+[m] => 2 ADP[m] + carbamoyl-phosphate[m] + 3 H+[m] + Pi[m] Urea cycle 107 r1317 LymphNode-TM H2O[c] + Stearoyl-ACP[c] => [ACP][c] + H+[c] + stearate[c] Fatty acid biosynthesis 108 DCSPTN1COAtxc Skin-TM (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA[c] + ATP[c] + H2O[c] => (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA[p] + ADP[c] + H+[c] + Pi[c] Transport reactions 109 DOCO13ECOAtxc Skin-TM ATP[c] + H2O[c] + 13-Docosenoyl Coenzyme A[c] => ADP[c] + H+[c] + Pi[c] + 13-Docosenoyl Coenzyme A[p] Transport reactions 110 DOCOSCOAtxc Skin-TM ATP[c] + docosanoyl-CoA[c] + H2O[c] => ADP[c] + docosanoyl-CoA[p] + H+[c] + Pi[c] Transport reactions 111 EX_CE2915[e] Skin-TM beta-casomorphin[s] <=> beta-casomorphin[x] Exchange/demand reactions 112 EX_CE2916[e] Skin-TM neocasomorphin[s] <=> neocasomorphin[x] Exchange/demand reactions 113 EX_CE2917[e] Skin-TM apelin-13[s] <=> apelin-13[x] Exchange/demand reactions 114 EX_CE4722[e] Skin-TM beta-casomorphin (1-6)[s] <=> beta-casomorphin (1-6)[x] Exchange/demand reactions 115 EX_CE4723[e] Skin-TM neocasomorphin (1-5)[s] <=> neocasomorphin (1-5)[x] Exchange/demand reactions 116 EX_CE4724[e] Skin-TM apelin-(1-12)[s] <=> apelin-(1-12)[x] Exchange/demand reactions 117 EX_HC01939[e] Skin-TM haptoglobin[s] <=> haptoglobin[x] Exchange/demand reactions 118 EX_ptvstlac[e] Skin-TM pitavastatin-lactone[s] <=> pitavastatin-lactone[x] Exchange/demand reactions 119 EX_rsvlac[e] Skin-TM rosuvastatin-5S-lactone[s] <=> rosuvastatin-5S-lactone[x] Exchange/demand reactions 120 HMR_1846 Skin-TM glycolithocholate[c] + PAPS[c] => H+[c] + PAP[c] + sulfoglycolithocholate[c] Bile acid biosynthesis 121 HMR_1875 Skin-TM cholate[s] + GSH[c] + HCO3-[c] <=> cholate[c] + GSH[s] + HCO3-[s] Bile acid recycling 122 HMR_1876 Skin-TM glycocholate[s] + GSH[c] + HCO3-[c] <=> glycocholate[c] + GSH[s] + HCO3-[s] Bile acid recycling 123 HMR_1877 Skin-TM GSH[c] + HCO3-[c] + taurocholate[s] <=> GSH[s] + HCO3-[s] + taurocholate[c] Bile acid recycling 124 HMR_1880 Skin-TM cholate[s] + glutathionyl-leukotriene C4[c] + HCO3-[c] <=> cholate[c] + glutathionyl-leukotriene C4[s] + HCO3-[s] Bile acid recycling 125 HMR_1881 Skin-TM cholate[s] + HCO3-[c] + S-glutathionyl-2-4-dinitrobenzene[c] <=> cholate[c] + HCO3-[s] + S-glutathionyl-2-4-dinitrobenzene[s] Bile acid recycling 126 HMR_1882 Skin-TM cholate[s] + HCO3-[c] + S-glutathionyl-ethacrynic acid[c] <=> cholate[c] + HCO3-[s] + S-glutathionyl-ethacrynic acid[s] Bile acid recycling 127 HMR_1883 Skin-TM glutathionyl-leukotriene C4[c] + glycocholate[s] + HCO3-[c] <=> glutathionyl-leukotriene C4[s] + glycocholate[c] + HCO3-[s] Bile acid recycling 128 HMR_1884 Skin-TM glycocholate[s] + HCO3-[c] + S-glutathionyl-2-4-dinitrobenzene[c] <=> glycocholate[c] + HCO3-[s] + S-glutathionyl-2-4-dinitrobenzene[s] Bile acid recycling 129 HMR_1886 Skin-TM chenodiol[s] + glutathionyl-leukotriene C4[c] + HCO3-[c] <=> chenodiol[c] + glutathionyl-leukotriene C4[s] + HCO3-[s] Bile acid recycling 130 HMR_1887 Skin-TM chenodiol[s] + HCO3-[c] + S-glutathionyl-2-4-dinitrobenzene[c] <=> chenodiol[c] + HCO3-[s] + S-glutathionyl-2-4-dinitrobenzene[s] Bile acid recycling 131 HMR_1888 Skin-TM chenodiol[s] + HCO3-[c] + S-glutathionyl-ethacrynic acid[c] <=> chenodiol[c] + HCO3-[s] + S-glutathionyl-ethacrynic acid[s] Bile acid recycling 132 HMR_1891 Skin-TM HCO3-[c] + S-glutathionyl-ethacrynic acid[c] + taurocholate[s] <=> HCO3-[s] + S-glutathionyl-ethacrynic acid[s] + taurocholate[c] Bile acid recycling 133 HMR_1892 Skin-TM glutathionyl-leukotriene C4[c] + HCO3-[c] + taurochenodeoxycholate[s] <=> glutathionyl-leukotriene C4[s] + HCO3-[s] + taurochenodeoxycholate[c] Bile acid recycling 134 HMR_1893 Skin-TM HCO3-[c] + S-glutathionyl-2-4-dinitrobenzene[c] + taurochenodeoxycholate[s] <=> HCO3-[s] + S-glutathionyl-2-4-dinitrobenzene[s] + taurochenodeoxycholate[c] Bile acid recycling 135 HMR_1894 Skin-TM HCO3-[c] + S-glutathionyl-ethacrynic acid[c] + taurochenodeoxycholate[s] <=> HCO3-[s] + S-glutathionyl-ethacrynic acid[s] + taurochenodeoxycholate[c] Bile acid recycling 136 HMR_1898 Skin-TM glutathionyl-leukotriene C4[c] + HCO3-[c] + noradrenaline[s] <=> glutathionyl-leukotriene C4[s] + HCO3-[s] + noradrenaline[c] Transport reactions 137 HMR_1899 Skin-TM HCO3-[c] + noradrenaline[s] + S-glutathionyl-2-4-dinitrobenzene[c] <=> HCO3-[s] + noradrenaline[c] + S-glutathionyl-2-4-dinitrobenzene[s] Transport reactions 138 HMR_1900 Skin-TM HCO3-[c] + noradrenaline[s] + S-glutathionyl-ethacrynic acid[c] <=> HCO3-[s] + noradrenaline[c] + S-glutathionyl-ethacrynic acid[s] Transport reactions 139 HMR_1903 Skin-TM HCO3-[c] + serotonin[s] + S-glutathionyl-ethacrynic acid[c] <=> HCO3-[s] + serotonin[c] + S-glutathionyl-ethacrynic acid[s] Transport reactions 140 HMR_1905 Skin-TM acetylcholine[s] + HCO3-[c] + S-glutathionyl-2-4-dinitrobenzene[c] <=> acetylcholine[c] + HCO3-[s] + S-glutathionyl-2-4-dinitrobenzene[s] Transport reactions 141 HMR_1907 Skin-TM dopamine[s] + glutathionyl-leukotriene C4[c] + HCO3-[c] <=> dopamine[c] + glutathionyl-leukotriene C4[s] + HCO3-[s] Transport reactions 142 HMR_3986 Skin-TM 2 chitin-component[s] + H2O[s] => chitobiose[s] Amino sugar and nucleotide sugar metabolism 143 HMR_4498 Skin-TM [ACP][c] + H2O[c] => apo-[ACP][c] + H+[c] + phosphopantetheine[c] Pantothenate and CoA biosynthesis 144 HMR_5214 Skin-TM haptoglobin[s] => haptoglobin[l] Transport reactions 145 HMR_5274 Skin-TM 405 ATP[l] + 810 H2O[l] + haptoglobin[l] => 405 ADP[l] + 30 alanine[l] + 9 arginine[l] + 21 asparagine[l] + 25 aspartate[l] + 12 cysteine[l] + 25 glutamate[l] + 17 glutamine[l] + 31 glycine[l] + 411 H+[l] + 13 histidine[l] + 18 isoleucine[l] + 31 leucine[l] + 35 lysine[l] + 5 methionine[l] + 8 phenylalanine[l] + 405 Pi[l] + 21 proline[l] + 18 serine[l] + 22 threonine[l] + 8 tryptophan[l] + 21 tyrosine[l] + 36 valine[l] Protein degradation 146 HMR_8048 Skin-TM paclitaxel[c] <=> paclitaxel[s] Transport reactions 147 HMR_8049 Skin-TM H+[c] + NADPH[c] + O2[c] + paclitaxel[c] => 6-hydroxypaclitaxel[c] + H2O[c] + NADP+[c] Metabolism of xenobiotics by cytochrome P450 148 HMR_9419 Skin-TM paclitaxel[s] <=> paclitaxel[x] Exchange/demand reactions 149 LGNCCOAtcx Skin-TM ATP[c] + H2O[c] + tetracosanoyl-CoA[c] => ADP[c] + H+[c] + Pi[c] + tetracosanoyl-CoA[p] Transport reactions 150 NRVNCCOAtxc Skin-TM (15Z)-tetracosenoyl-CoA[c] + ATP[c] + H2O[c] => (15Z)-tetracosenoyl-CoA[p] + ADP[c] + H+[c] + Pi[c] Transport reactions 151 PTVSTLACitr Skin-TM pitavastatin-lactone[r] <=> pitavastatin-lactone[c] Drug metabolism 152 PTVSTLACtev Skin-TM pitavastatin-lactone[c] <=> pitavastatin-lactone[s] Drug metabolism 153 RE0936E Skin-TM H2O[s] + beta-casomorphin[s] <=> isoleucine[s] + beta-casomorphin (1-6)[s] Miscellaneous 154 RE0937E Skin-TM H2O[s] + neocasomorphin[s] <=> isoleucine[s] + neocasomorphin (1-5)[s] Miscellaneous 155 RE0938E Skin-TM H2O[s] + apelin-13[s] <=> phenylalanine[s] + apelin-(1-12)[s] Miscellaneous 156 RSVLACteb Skin-TM ATP[c] + H2O[c] + rosuvastatin-5S-lactone[c] => ADP[c] + H+[c] + Pi[c] + rosuvastatin-5S-lactone[s] Drug metabolism 157 TCASULT Skin-TM PAPS[c] + taurocholate[c] => H+[c] + PAP[c] + Taurocholic acid 3-sulfate[c] Bile acid biosynthesis 158 r0946 Skin-TM citrulline[c] + ornithine[s] <=> citrulline[s] + ornithine[c] Transport reactions 159 r1317 Skin-TM H2O[c] + Stearoyl-ACP[c] => [ACP][c] + H+[c] + stearate[c] Fatty acid biosynthesis 160 3DHDCAS Brain-TM 3alpha,12alpha-dihydroxy-5beta-cholanate[c] + H+[c] + NADPH[c] + O2[c] => 2 H2O[c] + NADP+[c] + 3-dehydro-Deoxycholate[c] Bile acid biosynthesis 161 3DHDCAabc Brain-TM ATP[c] + H2O[c] + 3-dehydro-Deoxycholate[c] => ADP[c] + H+[c] + Pi[c] + 3-dehydro-Deoxycholate[s] Transport reactions 162 3DHLCAS Brain-TM H+[c] + lithocholate[c] + NADPH[c] + O2[c] => 2 H2O[c] + NADP+[c] + 3-dehydro-Lithocholate[c] Bile acid biosynthesis 163 3DHLCAabc Brain-TM ATP[c] + H2O[c] + 3-dehydro-Lithocholate[c] => ADP[c] + H+[c] + Pi[c] + 3-dehydro-Lithocholate[s] Transport reactions 164 ALLOP1tu Brain-TM Na+[s] + allopurinol[s] => Na+[c] + allopurinol[c] Drug metabolism 165 AM1CSAhr Brain-TM H+[r] + NADPH[r] + O2[r] + cyclosporine[r] => H2O[r] + NADP+[r] + AM1 (cyclosporine)[r] Drug metabolism 166 AM9CSAhr Brain-TM H+[r] + NADPH[r] + O2[r] + cyclosporine[r] => H2O[r] + NADP+[r] + AM9 (cyclosporine)[r] Drug metabolism 167 C05769te Brain-TM ATP[c] + coproporphyrin I[c] + H2O[c] => ADP[c] + coproporphyrin I[s] + H+[c] + Pi[c] Transport reactions 168 CE1273t1 Brain-TM ATP[c] + H2O[c] + 5beta-cholestane-3alpha,7alpha,12alpha,24s,25-pentol[c] => ADP[c] + H+[c] + Pi[c] + 5beta-cholestane-3alpha,7alpha,12alpha,24s,25-pentol[s] Transport reactions 169 CE1273t2 Brain-TM HCO3-[s] + 5beta-cholestane-3alpha,7alpha,12alpha,24s,25-pentol[c] <=> HCO3-[c] + 5beta-cholestane-3alpha,7alpha,12alpha,24s,25-pentol[s] Transport reactions 170 CSAitr Brain-TM cyclosporine[c] <=> cyclosporine[r] Drug metabolism 171 EX_3dhdchol[e] Brain-TM 3-dehydro-Deoxycholate[s] <=> 3-dehydro-Deoxycholate[x] Exchange/demand reactions 172 EX_3dhlchol[e] Brain-TM 3-dehydro-Lithocholate[s] <=> 3-dehydro-Lithocholate[x] Exchange/demand reactions 173 EX_CE1273[e] Brain-TM 5beta-cholestane-3alpha,7alpha,12alpha,24s,25-pentol[s] <=> 5beta-cholestane-3alpha,7alpha,12alpha,24s,25-pentol[x] Exchange/demand reactions 174 EX_thyochol[e] Brain-TM Taurohyocholic acid; N-(3alpha,6alpha,7alpha-Trihydroxy-5beta-cholan-24-oyl)taurine[s] <=> Taurohyocholic acid; N-(3alpha,6alpha,7alpha-Trihydroxy-5beta-cholan-24-oyl)taurine[x] Exchange/demand reactions 175 GDCASULT Brain-TM glycodeoxycholate[c] + PAPS[c] => H+[c] + PAP[c] + Glycodeoxycholic acid 3-sulfate[c] Bile acid biosynthesis 176 HMR_10083 Brain-TM taurohyocholic acid[s] <=> taurohyocholic acid[x] Exchange/demand reactions 177 HMR_10084 Brain-TM glycohyocholic acid[s] <=> glycohyocholic acid[x] Exchange/demand reactions 178 HMR_10085 Brain-TM glycohyodeoxycholic acid[s] <=> glycohyodeoxycholic acid[x] Exchange/demand reactions 179 HMR_10087 Brain-TM hyocholic acid[s] <=> hyocholic acid[x] Exchange/demand reactions 180 HMR_10101 Brain-TM ATP[c] + H2O[c] + taurohyocholic acid[c] => ADP[c] + H+[c] + Pi[c] + taurohyocholic acid[s] Transport reactions 181 HMR_10102 Brain-TM ATP[c] + H2O[c] + glycohyocholic acid[c] => ADP[c] + H+[c] + Pi[c] + glycohyocholic acid[s] Transport reactions 182 HMR_10103 Brain-TM ATP[c] + H2O[c] + hyocholic acid[c] => ADP[c] + H+[c] + Pi[c] + hyocholic acid[s] Transport reactions 183 HMR_10105 Brain-TM ATP[c] + CoA[c] + hyocholic acid[c] => AMP[c] + PPi[c] + hyocholoyl-CoA[c] Bile acid biosynthesis 184 HMR_10107 Brain-TM taurine[c] + hyocholoyl-CoA[c] => CoA[c] + H+[c] + taurohyocholic acid[c] Bile acid biosynthesis 185 HMR_10108 Brain-TM glycine[c] + hyocholoyl-CoA[c] => CoA[c] + H+[c] + glycohyocholic acid[c] Bile acid biosynthesis 186 HMR_10119 Brain-TM 2 Na+[s] + hyocholic acid[s] => 2 Na+[c] + hyocholic acid[c] Transport reactions 187 HMR_10121 Brain-TM ATP[c] + CoA[c] + hyodeoxycholate[c] => AMP[c] + H+[c] + PPi[c] + hyodeoxycholoyl-CoA[c] Bile acid biosynthesis 188 HMR_10123 Brain-TM taurine[c] + hyodeoxycholoyl-CoA[c] => CoA[c] + H+[c] + tauro-hyodeoxycholic acid[c] Bile acid biosynthesis 189 HMR_10124 Brain-TM glycine[c] + hyodeoxycholoyl-CoA[c] => CoA[c] + H+[c] + glycohyodeoxycholic acid[c] Bile acid biosynthesis 190 HMR_10125 Brain-TM ATP[c] + H2O[c] + tauro-hyodeoxycholic acid[c] => ADP[c] + H+[c] + Pi[c] + tauro-hyodeoxycholic acid[s] Transport reactions 191 HMR_10126 Brain-TM ATP[c] + H2O[c] + glycohyodeoxycholic acid[c] => ADP[c] + H+[c] + Pi[c] + glycohyodeoxycholic acid[s] Transport reactions 192 HMR_10132 Brain-TM tauro-hyodeoxycholic acid[s] <=> tauro-hyodeoxycholic acid[x] Exchange/demand reactions 193 HMR_1573 Brain-TM acetoacetyl-CoA[m] + acetyl-CoA[m] + H2O[m] => CoA[m] + H+[m] + HMG-CoA[m] Terpenoid backbone biosynthesis 194 HMR_1834 Brain-TM 3alpha,12alpha-dihydroxy-5beta-cholanate[c] + glycine[c] + H+[c] <=> glycodeoxycholate[c] + H2O[c] Bile acid biosynthesis 195 HMR_1838 Brain-TM 2 H+[c] + lithocholate[c] + NADPH[c] + O2[c] => H2O[c] + hyodeoxycholate[c] + NADP+[c] Bile acid biosynthesis 196 HMR_1969 Brain-TM dehydroepiandrosterone[c] + PAPS[c] => dehydroepiandrosterone sulfate[c] + H+[c] + PAP[c] Androgen metabolism 197 HMR_4910 Brain-TM 3 Na+[s] + Pi[s] => 3 Na+[c] + Pi[c] Transport reactions 198 HMR_4994 Brain-TM spermidine[c] <=> spermidine[s] Transport reactions 199 HMR_5013 Brain-TM spermine[c] <=> spermine[s] Transport reactions 200 HMR_5390 Brain-TM H2O[c] + methionine[c] + O2[c] => 4-methylthio-2-oxobutanoic acid[c] + H+[c] + H2O2[c] + NH3[c] Cysteine and methionine metabolism 201 HMR_6770 Brain-TM H2O[c] + O2[c] + tyrosine[c] => 4-hydroxyphenylpyruvate[c] + H+[c] + H2O2[c] + NH3[c] Phenylalanine, tyrosine and tryptophan biosynthesis 202 HMR_8147 Brain-TM glucosylceramide pool[g] + UDP-galactose[g] => H+[g] + LacCer pool[g] + UDP[g] Sphingolipid metabolism 203 HMR_8173 Brain-TM GM2alpha[g] + UDP-galactose[g] => GM1alpha[g] + H+[g] + UDP[g] Sphingolipid metabolism 204 HMR_8174 Brain-TM CMP-N-acetylneuraminate[g] + GM1alpha[g] => CMP[g] + GD1beta[g] + H+[g] Sphingolipid metabolism 205 HMR_8284 Brain-TM type II H glycolipid[g] + UDP-N-acetyl-D-galactosamine[g] => acgalfuc12gal14acglcgalgluside heparan sulfate[g] + H+[g] + UDP[g] Blood group biosynthesis 206 HMR_8285 Brain-TM acgalfuc12gal14acglcgalgluside heparan sulfate[g] + UDP-galactose[g] => galacgalfuc12gal14acglcgalgluside heparan sulfate[g] + H+[g] + UDP[g] Blood group biosynthesis 207 HMR_8286 Brain-TM galacgalfuc12gal14acglcgalgluside heparan sulfate[g] + GDP-L-fucose[g] => GDP[g] + H+[g] + type III H glycolipid[g] Blood group biosynthesis 208 HMR_8292 Brain-TM UDP-N-acetyl-D-galactosamine[g] + VI2Fuc-nLc6[g] => acgalfucgalacglcgal14acglcgalgluside heparan sulfate[g] + H+[g] + UDP[g] Blood group biosynthesis 209 HMR_8293 Brain-TM acgalfucgalacglcgal14acglcgalgluside heparan sulfate[g] + UDP-galactose[g] => galacgalfucgalacglcgal14acglcgalgluside heparan sulfate[g] + H+[g] + UDP[g] Blood group biosynthesis 210 HMR_8294 Brain-TM galacgalfucgalacglcgal14acglcgalgluside heparan sulfate[g] + GDP-L-fucose[g] => fucgalacgalfucgalacglcgal14acglcgalgluside heparan sulfate[g] + GDP[g] + H+[g] Blood group biosynthesis 211 HMR_8317 Brain-TM G00077[g] + UDP-galactose[g] => H+[c] + iso-nLc8Cer[c] + UDP[g] Blood group biosynthesis 212 HMR_9649 Brain-TM coproporphyrin I[c] <=> coproporphyrin I[s] Transport reactions 213 HMR_9701 Brain-TM coproporphyrin I[s] <=> coproporphyrin I[x] Exchange/demand reactions 214 NAt Brain-TM Na+[s] <=> Na+[c] Transport reactions 215 NH4t3r Brain-TM H+[s] + NH4+[c] <=> H+[c] + NH4+[s] Transport reactions 216 TCDCA6AH Brain-TM NADPH[c] + O2[c] + taurochenodeoxycholate[c] => H2O[c] + NADP+[c] + Taurohyocholic acid; N-(3alpha,6alpha,7alpha-Trihydroxy-5beta-cholan-24-oyl)taurine[c] Bile acid biosynthesis 217 THYOCHOLabc Brain-TM ATP[c] + H2O[c] + Taurohyocholic acid; N-(3alpha,6alpha,7alpha-Trihydroxy-5beta-cholan-24-oyl)taurine[c] => ADP[c] + H+[c] + Pi[c] + Taurohyocholic acid; N-(3alpha,6alpha,7alpha-Trihydroxy-5beta-cholan-24-oyl)taurine[s] Transport reactions 218 r0993 Brain-TM ATP[c] + H2O[c] + Chenodeoxycholate[c] => ADP[c] + H+[c] + Pi[c] + Chenodeoxycholate[s] Transport reactions