smiles,Target,Label,Value (nM),Measurement,Source,Detailed_label
CC[C@](C)(N)c1cnc(OC)c2cnc(Nc3ccc4c(n3)CC(C)(C)OC4=O)cc12,HPK1,active,0.15,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@](C)(N)c1cnc(OC)c2cnc(Nc3ccc4c(n3)CC(C)(C)OC4=O)cc12,HPK1,active,0.15,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CCOc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)[C@H](C)[C@H](C)OC4=O)ncc12,HPK1,active,3.35,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CCOc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)[C@@H](C)[C@@H](C)OC4=O)ncc12,HPK1,active,3.35,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CCOc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)[C@H](C)[C@@H](C)OC4=O)ncc12,HPK1,active,0.39,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CCOc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)[C@@H](C)[C@H](C)OC4=O)ncc12,HPK1,active,0.16,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)[C@@H](C)C(C)(C)OC4=O)ncc12,HPK1,active,0.1,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)[C@H](C)C(C)(C)OC4=O)ncc12,HPK1,active,0.18,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CCOc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)CC(C)(C)OC4=O)ncc12,HPK1,active,0.25,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CCNc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)CC(C)(C)OC4=O)ncc12,HPK1,active,0.36,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)[C@@H]3CCC[C@@H]3OC4=O)ncc12,HPK1,active,0.26,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)[C@H]3CCC[C@H]3OC4=O)ncc12,HPK1,active,0.26,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3cnc(C#N)c(N4CCC[C@@H]4C)n3)ncc12,HPK1,active,1.01,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1cnc(C(C)(C)N)c2cc(Nc3ccc4c(n3)CC(C)(C)OC4=O)ncc12,HPK1,active,0.94,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CCOc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)C(C)(C)OC4=O)ncc12,HPK1,active,1.03,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CCOc1ncc(C(C)(C)N)c2c1=CNC(Nc1ccc3c(n1)[C@H](C)COC3=O)C=2,HPK1,active,0.23,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CCOc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)[C@@H](C)COC4=O)ncc12,HPK1,active,0.23,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CCOc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)C[C@@H](C)OC4=O)ncc12,HPK1,active,0.57,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CCOc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)C[C@H](C)OC4=O)ncc12,HPK1,active,0.57,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)[C@H](C)[C@H](C)OC4=O)ncc12,HPK1,active,0.85,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)[C@@H](C)[C@@H](C)OC4=O)ncc12,HPK1,active,0.85,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)[C@H](C)[C@@H](C)OC4=O)ncc12,HPK1,active,0.2,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)[C@@H](C)[C@H](C)OC4=O)ncc12,HPK1,active,0.14,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)CC(C)(C)OC4=O)ncc12,HPK1,active,0.17,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CNc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)CC(C)(C)OC4=O)ncc12,HPK1,active,0.41,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)CC(C)(C)CC4=O)ncc12,HPK1,active,0.24,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)CC3(CC3)OC4=O)ncc12,HPK1,active,0.13,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H](F)c1nc(Nc2cc3c(C(C)(C)N)cnc(OC)c3cn2)cnc1C#N,HPK1,active,3.57,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](F)c1nc(Nc2cc3c(C(C)(C)N)cnc(OC)c3cn2)cnc1C#N,HPK1,active,3.57,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3cnc(C#N)c(C(C)(C)F)n3)ncc12,HPK1,active,3.98,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3ccc(C#N)c(C(C)(C)F)n3)ncc12,HPK1,active,0.67,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3ccnc(N4CCC[C@@H]4C)n3)ncc12,HPK1,active,0.3,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)C(C)(C)OC4=O)ncc12,HPK1,active,0.55,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)C[C@H](C)OC4=O)ncc12,HPK1,active,0.47,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)C[C@@H](C)OC4=O)ncc12,HPK1,active,0.47,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)[C@H](C)COC4=O)ncc12,HPK1,active,0.5,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)[C@@H](C)COC4=O)ncc12,HPK1,active,0.5,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H](C)c1nc(Nc2cc3c(C(C)(C)N)cnc(OC)c3cn2)cnc1C#N,HPK1,active,0.73,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](C)c1nc(Nc2cc3c(C(C)(C)N)cnc(OC)c3cn2)cnc1C#N,HPK1,active,0.73,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](C)c1nc(Nc2cc3c(C(C)(C)N)cnc(OC)c3cn2)ccc1C#N,HPK1,active,0.4,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H](C)c1nc(Nc2cc3c(C(C)(C)N)cnc(OC)c3cn2)ccc1C#N,HPK1,active,0.4,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CNC(C)(C)c1cnc(OC)c2cnc(Nc3ccnc(C(C)(C)F)n3)cc12,HPK1,active,4.02,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CCOc1ncc(C(C)(C)N)c2cc(Nc3ccnc(C(C)(C)F)n3)ncc12,HPK1,active,2.5,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H](C)n1nc(Nc2cc3c(C(C)(C)N)cnc(OC)c3cn2)ccc1=O,HPK1,active,0.64,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](C)n1nc(Nc2cc3c(C(C)(C)N)cnc(OC)c3cn2)ccc1=O,HPK1,active,0.64,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3ccnc(N4CC[C@@H]4C)n3)ncc12,HPK1,active,0.29,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)CCOC4=O)ncc12,HPK1,active,0.31,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)CCNC4=O)ncc12,HPK1,active,0.33,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3cnc(C#N)c(C(C)C)n3)ncc12,HPK1,active,2.73,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)CCCC4=O)ncc12,HPK1,active,0.55,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3ccnc(C(C)(C)F)n3)ncc12,HPK1,active,0.91,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CNc1ncc(C(C)(C)N)c2cc(Nc3ccnc(C(C)(C)F)n3)ncc12,HPK1,active,3.31,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(C(C)(C)N)c2cc(Nc3ccnc(C(C)(C)F)n3)ncc12,HPK1,active,0.37,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3ccnc(OC(C)C)n3)ncc12,HPK1,active,0.42,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CNc1ncc(C(C)(C)N)c2cc(Nc3ccnc(C(C)(C)C)n3)ncc12,HPK1,active,1.6,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(-c4cnc5c(c4C)NCCO5)cc32)c1C,HPK1,active,0.05,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3c(F)cc(-c4cnc5c(c4C)NCCO5)cc32)c1C,HPK1,active,0.09,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)/C(=C/c2c[nH]c4ccccc24)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.42,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)/C(=C/c2ncc[nH]2)C(=O)N3)cnc2c1NCC1(CC1)O2,HPK1,active,2.13,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)/C(=C/c2cn[nH]c2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.26,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1n[nH]cc1/C=C1\C(=O)Nc2ccc(-c3cnc4c(c3C)NCCO4)cc21,HPK1,active,0.32,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3c(c2C)NCCO3)cc2c1NC(=O)/C2=C\c1cn[nH]c1,HPK1,active,4.33,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(Cl)c3c(c2)/C(=C/c2cn[nH]c2)C(=O)N3)cnc2c1NCCO2,HPK1,active,6.9,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(F)c3c(c2C)/C(=C/c2cn[nH]c2)C(=O)N3)cnc2c1NCCO2,HPK1,active,1.03,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(F)c3c(c2C)/C(=C/c2cc4ncccc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.31,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(F)c3c(c2C)/C(=C/c2cc4ccncc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.41,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)/C(=C/c2cc4ccccc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.05,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)/C(=C/c2cc4cccnc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,1.1,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)/C(=C/c2cc4cnccc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.06,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)/C(=C/c2nc4ccccc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.28,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)/C(=C/c2cc4ccncc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.11,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)/C(=C/c2cc4ncccc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.05,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cnc3c(c2)/C(=C/c2cc4ccccc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,1.24,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(F)c3c(c2C)/C(=C/c2cc4ccccc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.51,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(F)c3c(c2C)/C(=C/c2cc4cnccc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.27,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(F)c3c(c2)/C(=C/c2cc4ccccc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.16,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc3c(cc2F)NC(=O)/C3=C\c2cc3ccccc3[nH]2)cnc2c1NCCO2,HPK1,active,0.16,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(F)c3c(c2)/C(=C/c2cc4cnccc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.1,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc3c(cc2Cl)NC(=O)/C3=C\c2cc3ccccc3[nH]2)cnc2c1NCCO2,HPK1,active,0.19,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc3c(cc2F)NC(=O)/C3=C\c2cc3cnccc3[nH]2)cnc2c1NCCO2,HPK1,active,0.16,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc3c(cc2Cl)NC(=O)/C3=C\c2cc3cnccc3[nH]2)cnc2c1NCCO2,HPK1,active,0.16,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cnc3c(c2)/C(=C/c2cc4cnccc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,1.13,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(F)c3c(c2)/C(=C/c2cc4ncccc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.05,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(F)c3c(c2)/C(=C/c2cc4ccncc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.17,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc3c(cc2F)NC(=O)/C3=C\c2cc3ncccc3[nH]2)cnc2c1NCCO2,HPK1,active,0.05,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc3c(cc2F)NC(=O)/C3=C\c2cc3ccncc3[nH]2)cnc2c1NCCO2,HPK1,active,0.13,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(cc1-c1cnc3c(c1)NCCO3)/C(=C/c1cc3cnccc3[nH]1)C(=O)N2,HPK1,active,5.73,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cnc3c(c2)NCCO3)cc(F)c2c1/C(=C/c1cc3cnccc3[nH]1)C(=O)N2,HPK1,active,9.3,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(cc1-c1cnc3c(c1C)NCCO3)/C(=C/c1cc3cnccc3[nH]1)C(=O)N2,HPK1,active,0.07,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)/C(=C/c2cc4cnccc4[nH]2)C(=O)N3)ccc2c1NC(=O)CO2,HPK1,active,7.03,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(cc1-c1cnc3c(c1C)NCCO3)/C(=C/c1cc3ccncc3[nH]1)C(=O)N2,HPK1,active,0.69,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(cc1-c1cnc3c(c1C)NCCO3)/C(=C/c1cc3ncccc3[nH]1)C(=O)N2,HPK1,active,0.11,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CC/C(=C1/C(=O)Nc2ccc(-c3cnc4c(c3C)NCCO4)cc21)c1cnc[nH]1,HPK1,active,1,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(F)c3c(c2)/C(=C/c2cnc(C4CC4)[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.05,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)/C(=C/c2cnc(C4CC4)[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.13,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)/C(=C/c2ncc[nH]2)C(=O)N3)cnc2c1NC(=O)C1(CC1)O2,HPK1,active,5.66,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)/C(=C/c2cnc[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.26,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)/C(=C/c2ccn[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.97,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)/C(=C/c2ncc[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.77,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)/C(=C/c2ccc[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.05,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c[nH]c(/C=C2\C(=O)Nc3ccc(-c4cnc5c(c4C)NCCO5)cc32)c1,HPK1,active,0.05,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)/C(=C/c2cnn[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,1.64,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c[nH]c(/C=C2\C(=O)Nc3c(C)cc(-c4cnc5c(c4C)NCCO5)cc32)c1,HPK1,active,2.93,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(F)c3c(c2)/C(=C/c2ccc[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.05,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c[nH]c(/C=C2\C(=O)Nc3c(F)cc(-c4cnc5c(c4C)NCCO5)cc32)c1,HPK1,active,0.05,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)/C(=C/c2cc(C#N)c[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.07,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(Cl)c3c(c2)/C(=C/c2ccc[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,1.98,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c[nH]c(/C=C2\C(=O)Nc3c(Cl)cc(-c4cnc5c(c4C)NCCO5)cc32)c1,HPK1,active,2.61,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)/C(=C/c2cc(Br)c[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.16,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)/C(=C/c2cccs2)C(=O)N3)cnc2c1NCCO2,HPK1,active,1.88,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)/C(=C/c2ccns2)C(=O)N3)cnc2c1NCCO2,HPK1,active,3.02,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(/C=C2\C(=O)Nc3ccc(-c4cnc5c(c4C)NCCO5)cc32)[nH]1,HPK1,active,0.05,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ncc(/C=C2\C(=O)Nc3ccc(-c4cnc5c(c4C)NCCO5)cc32)[nH]1,HPK1,active,0.07,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(F)c3c(c2C)/C(=C/c2ccc[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.29,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
C/C(=C1/C(=O)Nc2ccc(-c3cnc4c(c3C)NCCO4)cc21)c1cnc[nH]1,HPK1,active,0.44,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c[nH]c(/C=C2\C(=O)Nc3c(F)cc(-c4cnc5c(c4C)NCCO5)c(C)c32)c1,HPK1,active,0.51,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(F)c3c(c2C)/C(=C/c2cc(C#N)c[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.67,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ncc(/C=C2\C(=O)Nc3c(F)cc(-c4cnc5c(c4C)NCCO5)cc32)[nH]1,HPK1,active,0.22,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ncc(/C=C2\C(=O)Nc3cc(Cl)c(-c4cnc5c(c4C)NCCO5)cc32)[nH]1,HPK1,active,0.29,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ncc(/C=C2\C(=O)Nc3cc(F)c(-c4cnc5c(c4C)NCCO5)cc32)[nH]1,HPK1,active,0.18,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CCc1nc(C)c(/C=C2\C(=O)Nc3ccc(-c4cnc5c(c4C)NCCO5)cc32)[nH]1,HPK1,active,0.12,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ncc(/C=C2\C(=O)Nc3c(F)cc(-c4cnc5c(c4)NCCO5)c(C)c32)[nH]1,HPK1,active,7.43,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ncc(/C=C2\C(=O)Nc3cc(C)c(-c4cnc5c(c4C)NCCO5)cc32)[nH]1,HPK1,active,0.19,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ncc(/C=C2\C(=O)Nc3c(F)cc(-c4cnc5c(c4C)NCCO5)c(C)c32)[nH]1,HPK1,active,0.15,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ncc(/C=C2\C(=O)Nc3ccc(-c4ccc5c(c4C)NCCO5)cc32)[nH]1,HPK1,active,1.95,ic50,WO2020237025A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3cc(F)c(-c4cnc5c(c4C)NCCO5)cc32)c1C,HPK1,active,0.05,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOCCN(C)C(=O)c1cnn(-c2nc(-c3cc(C)c4c(c3)CN(C)CC4)cnc2N)c1,HPK1,active,5.3,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc(N)c(Oc3cnn(C(C)C)c3)n2)cc2c1CCN(C)C2,HPK1,active,8.4,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc(N)c(Oc3cnn(CC4(F)CCOCC4)c3)n2)cc2c1CCN(C)C2,HPK1,active,4.5,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc(N)c(Oc3cnn(C(C)(C)CC#N)c3)n2)cc2c1CCN(C)C2,HPK1,active,8.3,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc(N)c(Oc3cnn([C@H]4CC[C@@](C)(O)CC4)c3)n2)cc2c1CCN(C)C2,HPK1,active,7.7,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc(N)c(-n3cc(C(=O)NC4CCOC4)cn3)n2)cc2c1CCN(C)C2,HPK1,active,8.9,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc(N)c(-n3cc(C(=O)NCc4ccc(F)cc4Cl)cn3)n2)cc2c1CCN(C)C2,HPK1,active,7.5,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc(N)c(-n3cc(C(=O)NC4CC4)cn3)n2)cc2c1CCN(C)C2,HPK1,active,4.2,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc(N)c(-n3cc(C(=O)NCC4CC4)cn3)n2)cc2c1CCN(C)C2,HPK1,active,6.6,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc(N)c(-n3cc(C(=O)NCCN4CCOCC4)cn3)n2)cc2c1CCN(C)C2,HPK1,active,8.9,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc(N)c(-n3cc(C(=O)N(C)C4CC4)cn3)n2)cc2c1CCN(C)C2,HPK1,active,5.9,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CNc1cc(-c2cnc(N)c(-n3cc(C(=O)N(C)C)cn3)n2)cc2c1CCN(C)C2,HPK1,active,9.7,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc(N)c(-n3cc(C(=O)N(C)c4ccccc4Cl)cn3)n2)cc2c1CCN(C)C2,HPK1,active,3.6,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc(N)c(OCc3ccnc(N)c3O[C@H]3CCOC3)n2)cc2c1CCN(C)C2,HPK1,active,6.6,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
COCCN(C)C(=O)c1cnn(-c2nc(-c3cc(C)c4c(c3)CN(C)CC4)cnc2N)c1,HPK1,active,6.3,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc(N)c(Oc3cnn(CCC#N)c3)n2)cc2c1CCN(C)C2,HPK1,active,6.5,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
[2H]C([2H])(Oc1nc(-c2cc(C)c3c(c2)CN(C)CC3)cnc1N)c1ccnc(N)c1,HPK1,active,5.1,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc(N)c(OCc3ccnc(N)c3OC3CCOCC3)n2)cc2c1CCN(C)C2,HPK1,active,8,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc(N)c(OCc3cc(N)nc(N)c3)n2)cc2c1CCN(C)C2,HPK1,active,4,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CNc1cc(-c2cnc(N)c(OCc3ccnc(N)c3)n2)cc2c1CCN(C)C2,HPK1,active,7,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
COc1cnc2[nH]ccc2c1COc1nc(-c2cc(C)c3c(c2)CN(C)CC3)cnc1N,HPK1,active,8.1,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc(N)c(OCc3ccnc(N)c3)n2)cc2c1CCN(C)C2,HPK1,active,7.2,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc(N)c(OCc3cc(N)ncc3OC3CC3)n2)cc2c1CCN(C)C2,HPK1,active,2.8,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc(N)c(OCc3ccncc3OC3CCOCC3)n2)cc2c1CCN(C)C2,HPK1,active,6.9,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc(N)c(Oc3cnn(C4CCN(C)CC4)c3)n2)cc2c1CCN(C)C2,HPK1,active,5.9,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CCOc1c(COc2nc(-c3cc(C)c4c(c3)CN(C)CC4)cnc2N)ccnc1N,HPK1,active,8.9,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc(N)c(OCc3ccncc3OCC3CCOCC3)n2)cc2c1CCN(C)C2,HPK1,active,9.3,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc(N)c(OCc3ccncc3OCc3ccccc3)n2)cc2c1CCN(C)C2,HPK1,active,8.2,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cnc(N)cc1COc1nc(-c2cc(C)c3c(c2)CN(C)CC3)cnc1N,HPK1,active,5.1,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc(N)c(OCc3ccncc3OC(C)C)n2)cc2c1CCN(C)C2,HPK1,active,7.6,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc(N)c(OCc3ccnc(C#CC(C)(C)O)c3)n2)cc2c1CCN(C)C2,HPK1,active,9.4,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc(N)c(OCc3ccnc(N)c3)n2)cc2c1CCN(C)C2,HPK1,active,5.2,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(-c4nnc(C5CC5)o4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
Cc1nnc(-c2cnc(Nc3ccc4c(c3)C(C)(C)OC4=O)nc2N[C@H](CO)c2ccccc2)o1,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(-c4nc(C56CCN(CC5)CC6)no4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2noc(-c3cnc(Nc4ccc5c(c4)C(C)(C)OC5=O)nc3N[C@H](CO)c3ccccc3)n2)CC1,HPK1,active,0.22,ic50,"BMS-Discovery of Orally Active Isofuranones as Potent, Selective Inhibitors of Hematopoetic Progenitor Kinase 1", not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(-c4nc(-c5ccncc5)no4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,1.2,ic50,"BMS-Discovery of Orally Active Isofuranones as Potent, Selective Inhibitors of Hematopoetic Progenitor Kinase 1", not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(-c4nc(C5CC5)no4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1noc(-c2cnc(Nc3ccc4c(c3)C(C)(C)OC4=O)nc2N[C@H](CO)c2ccccc2)n1,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1noc(-c2cnc(Nc3ccc4c(c3)C(C)(C)OC4=O)nc2N[C@H](CO)c2ccccc2)n1,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CCc1noc(-c2cnc(Nc3ccc4c(c3)C(C)(C)OC4=O)nc2N[C@H](CO)c2ccccc2)n1,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
Cc1noc(-c2cnc(Nc3ccc4c(c3)C(C)(C)OC4=O)nc2N[C@H](CO)c2ccccc2)n1,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)c1cnc(Nc2ccc3c(c2)C(C)(C)OC3=O)nc1N[C@H](CO)c1ccccc1,HPK1,active,7.3,ic50,"BMS-Discovery of Orally Active Isofuranones as Potent, Selective Inhibitors of Hematopoetic Progenitor Kinase 1", not Ki or Kd; not used in NCI fingerprint analysis
CCCNC(=O)c1cnc(Nc2ccc3c(c2)C(C)(C)OC3=O)nc1N[C@H](CO)c1ccccc1,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cnc(Nc2ccc3c(c2)C(C)(C)OC3=O)nc1N[C@H](CO)c1ccccc1,HPK1,active,5.1,ic50,"BMS-Discovery of Orally Active Isofuranones as Potent, Selective Inhibitors of Hematopoetic Progenitor Kinase 1", not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1cc2c(cnn2-c2cccc(N3CCN(C)CC3)n2)cc1C#N,HPK1,active,2,ic50,Merck-Identification of Potent Reverse Indazole Inhibitors for HPK1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1cc2c(cn1)cnn2-c1cccc(N2CC3CCC(C2)N3C)n1,HPK1,active,1.1,ic50,Merck-Identification of Potent Reverse Indazole Inhibitors for HPK1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1cc2c(cn1)cnn2-c1cccc(N2C[C@@H]3C[C@H]2CN3C)n1,HPK1,active,1.9,ic50,Merck-Identification of Potent Reverse Indazole Inhibitors for HPK1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1cc2c(cn1)cnn2-c1cccc(N2CC[C@H](N(C)C)C2)n1,HPK1,active,1.2,ic50,Merck-Identification of Potent Reverse Indazole Inhibitors for HPK1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1cc2c(cn1)cnn2-c1cc(Cl)cc(N2CCN(C)CC2)n1,HPK1,active,1.8,ic50,Merck-Identification of Potent Reverse Indazole Inhibitors for HPK1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1cc2c(cn1)cnn2-c1cccc(N2CCNCC2)n1,HPK1,active,3.8,ic50,Merck-Identification of Potent Reverse Indazole Inhibitors for HPK1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1cc2c(cn1)cnn2-c1ccnc(N2CCN(C)CC2)n1,HPK1,active,6.7,ic50,Merck-Identification of Potent Reverse Indazole Inhibitors for HPK1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1cc2c(cn1)cnn2-c1cccc(N2CCN(C)CC2)n1,HPK1,active,2.6,ic50,Merck-Identification of Potent Reverse Indazole Inhibitors for HPK1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2cc(-c3n[nH]c4ccc(-c5cnn6c5CCC6)cc34)ccn2)CC1,HPK1,active,9.1,ic50,Merck-Identification of Potent Reverse Indazole Inhibitors for HPK1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C(N)=O)c(NC3CCCC3)n1)CN(C)CC2,HPK1,medium,165,ec50,Merck-Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotheray Tool Compounds, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C(N)=O)c(Nc3ccccc3CO)n1)CN(C)CC2,HPK1,active,19,ec50,Merck-Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotheray Tool Compounds, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C(N)=O)c(Nc3ccccc3[C@H](C)OC)n1)CN(C)CC2,HPK1,active,12,ec50,Merck-Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotheray Tool Compounds, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C(N)=O)c(Nc3ccccc3C(C)OC)n1)CN(C)CC2,HPK1,active,60,ec50,Merck-Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotheray Tool Compounds, not Ki or Kd; not used in NCI fingerprint analysis
COCc1ccccc1Nc1nc(Nc2cc3c(cc2OC)CCN(C)C3)ncc1C(N)=O,HPK1,active,37,ec50,Merck-Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotheray Tool c(cc2OCompouds, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C(N)=O)c(Nc3ccccc3OC)n1)CN(C)CC2,HPK1,medium,180,ec50,Merck-Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotheray Tool Compounds, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C(N)=O)c(Nc3ccccc3C(C)(F)F)n1)CN(C)CC2,HPK1,medium,165,ec50,Merck-Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotheray Tool Compounds, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C(N)=O)c(Nc3ccccc3C(F)(F)F)n1)CN(C)CC2,HPK1,medium,167,ec50,Merck-Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotheray Tool Compounds, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C(N)=O)c(Nc3c(F)cccc3C(F)(F)F)n1)CN(C)CC2,HPK1,medium,108,ec50,Merck-Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotheray Tool Compounds, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C(N)=O)c(Nc3c(F)cccc3F)n1)CN(C)CC2,HPK1,active,65,ec50,Merck-Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotheray Tool Compounds, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C(N)=O)c(Nc3ccccc3S(N)(=O)=O)n1)CN(C)CC2,HPK1,active,0.052,ic50,Merck-Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotheray Tool Compounds, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C(N)=O)c(Nc3c(C)cccc3F)n1)CN(C)CC2,HPK1,medium,169,ec50,Merck-Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotheray Tool Compounds, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C(N)=O)c(Nc3ccccc3Br)n1)CN(C)CC2,HPK1,medium,146,ec50,Merck-Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotheray Tool Compounds, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C(N)=O)c(Nc3ccccc3)n1)CN(C)CC2,HPK1,medium,226,ec50,Merck-Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotheray Tool Compounds, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@]3(I)C[C@H](N5CCCCC5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC4(C(F)F)CC4)c(Cl)c(F)c3F)c21,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(F)c(Nc2nc(-c3ccc4c(c3)N([C@]3(C)C[C@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)NC1(C(F)F)CC1,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC4(C(F)F)CC4)cc(F)c3F)c21,HPK1,active,0.05,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC4(C(F)F)CC4)cc(F)c3F)c21,HPK1,active,0.07,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC4(CF)CC4)c(Cl)c(F)c3F)c21,HPK1,active,0.07,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)cc1Cl,HPK1,active,0.07,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NCC(F)F)c(Cl)cc3F)c21,HPK1,active,0.07,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c(F)c1Cl,HPK1,active,0.08,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c(F)c1Cl,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCC6(CC6)C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c(F)c1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCC6(CC6)C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c(F)c1Cl,HPK1,active,0.09,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c(F)c1Cl,HPK1,active,0.07,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC4(C(F)F)CC4)c(F)c(F)c3F)c21,HPK1,active,0.05,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1cc(Nc2nc(-c3cc4c(nc3F)C(C)(C)C(=O)N4[C@H]3C[C@@](C)(N4CCCC5(CC5)C4)C3)cc3ncn(C(C)C)c23)c(F)c(F)c1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c(F)c1F,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NCC(F)F)cc(Nc2nc(-c3cc4c(nc3F)C(C)(C)C(=O)N4[C@H]3C[C@@](C)(N4CCCC5(CC5)C4)C3)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.07,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.06,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C43CC3)nc(Nc3cc(C(=O)NCC(F)F)c(Cl)c(F)c3F)c21,HPK1,active,0.06,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cc4c(nc3F)C(C)(C)C(=O)N4[C@H]3C[C@@](C)(N4CCCCC4)C3)nc(Nc3cc(C(=O)NCC(F)F)c(Cl)c(F)c3F)c21,HPK1,active,0.09,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1cc(Nc2nc(-c3cc4c(nc3F)C(C)(C)C(=O)N4[C@H]3C[C@@](C)(N4CCCCC4)C3)cc3ncn(C(C)C)c23)c(F)c(F)c1C,HPK1,active,0.06,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1cc(Nc2nc(-c3cc4c(nc3F)C(C)(C)C(=O)N4[C@H]3C[C@@](C)(N4CCCC5(CC5)C4)C3)cc3ncn(C(C)C)c23)c(F)c(F)c1Cl,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NCC(F)F)cc(Nc2nc(-c3cc4c(nc3F)C(C)(C)C(=O)N4[C@H]3C[C@@](C)(N4CCCCC4)C3)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.07,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NCC(F)F)cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.03,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)NC(=O)c1cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c(F)c1Cl,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(F)c(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)NCC(F)F,HPK1,active,0.06,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC4CC4)c(Cl)c(F)c3F)c21,HPK1,active,0.06,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(F)c(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc(C(=O)NC2(C(F)F)CC2)c1Cl,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5C[C@H]6CC[C@@H]5C6)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC4(C(F)F)CC4)c(Cl)c(F)c3F)c21,HPK1,active,0.05,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1ccc(F)c(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c1,HPK1,active,0.09,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c(F)c1C,HPK1,active,0.04,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NC2(C(F)F)CC2)cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)CC4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.3,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NC2(C(F)F)CC2)cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.07,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)NC(=O)c1cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCC6CC6C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c(F)c1Cl,HPK1,active,0.05,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCC6CC6C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c(F)c1Cl,HPK1,active,0.04,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NCC(F)F)c(Cl)c(F)c3F)c21,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c(F)c1Cl,HPK1,active,0.05,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NC2(C(F)F)CC2)cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCC6CC6C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NC2(C(F)F)CC2)cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CC6CCC(C6)C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NC2(C(F)F)CC2)cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CC6CCC(C5)O6)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.3,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCC6CC6C5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC4(CF)CC4)c(Cl)c(F)c3F)c21,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCCC5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC4(C(F)F)CC4)c(Cl)c(F)c3F)c21,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCC6CC6C5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC4(C(F)F)CC4)c(Cl)c(F)c3F)c21,HPK1,active,0.08,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NC2(C(F)F)CC2)cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.04,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC4(C(F)F)CC4)c(Cl)c(F)c3F)c21,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1ccc(F)c(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c1,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c(F)c1C,HPK1,active,0.06,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NC2CC2)cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.07,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NC(C)C)cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.09,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(F)c(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)CC4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)NC1(C(F)F)CC1,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC4(C(F)F)CC4)ccc3F)c21,HPK1,active,0.06,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NCC(F)F)cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.06,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(F)c(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)NC1(C(F)F)CC1,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(F)c(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCOCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)NC1(C(F)F)CC1,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC4(CF)CC4)c(Cl)c(F)c3F)c21,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NC2(C(F)F)CC2)cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CC6CCC6C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.08,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NC2(C(F)F)CC2)cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCOCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.09,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC4(C(F)F)CC4)c(Cl)c(F)c3F)c21,HPK1,active,0.08,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(F)c(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C43CCOCC3)cc3ncn(C(C)C)c23)cc1C(=O)NC1(C(F)F)CC1,HPK1,active,0.07,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CC6CCC6C5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC4(C(F)F)CC4)c(Cl)c(F)c3F)c21,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC4(C(F)F)CC4)c(Cl)cc3F)c21,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCC[C@@H](F)C5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC4(C(F)F)CC4)c(Cl)c(F)c3F)c21,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CC[C@@H](F)C5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC4(C(F)F)CC4)c(Cl)c(F)c3F)c21,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCOCC5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC4(C(F)F)CC4)c(Cl)c(F)c3F)c21,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCOCC5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC4(C(F)F)CC4)c(Cl)c(F)c3F)c21,HPK1,active,0.01,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NC2(C(F)F)CC2)cc(Nc2nc(-c3cc4c(nc3F)C(C)(C)C(=O)N4[C@H]3C[C@@](C)(N4CCCCC4)C3)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.07,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NC2(C(F)F)CC2)cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCC6(CC6)C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.06,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NC2(C(F)F)CC2)cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5C[C@H]6COC[C@H]6C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NC2(C(F)F)CC2)cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)N[C@H](C)C(F)F,HPK1,active,0.07,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)N[C@@H](C)C(F)F,HPK1,active,0.07,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC[C@@H](C(F)F)C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(F)F)cc3ncn(C4CC4)c23)cc1C(N)=O,HPK1,active,0.9,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Oc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(C)=O)CC3)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CC2(C1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4cc(C(=O)NC(C)C)c(C)cc4F)n3)ccc12,HPK1,active,1.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CN(C(C)=O)C3)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.3,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C4COC4)CC3)cc3ncn(C(C)C)c23)cc1C(=O)NC1(CF)CC1,HPK1,active,0.09,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC[C@@H](F)C5)C3)C(=O)C43CCN(C4COC4)CC3)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](NC5CC(F)(F)C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.3,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](NC5CCC(F)(F)CC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C4CC4)c23)ccc1C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CC4CCC(C3)O4)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4cc(C(=O)NC(C)C)c(C)cc4F)n3)ccc12,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3C4CCC3COC4)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4cc(C(=O)NC(C)C)c(C)cc4F)n3)ccc12,HPK1,active,0.06,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(F)c(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)NC1(C(F)F)CC1,HPK1,active,0.3,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(F)c(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5C[C@H]6CC[C@@H]5C6)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)NC1(C(F)F)CC1,HPK1,active,0.09,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(F)c(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)NC1(C(F)F)CC1,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NC2(C(F)F)CC2)cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@H](N5C[C@H]6CC[C@@H]5C6)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)O)cc3ncn(C(C)C)c23)ccc1Cl,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCC(CC(F)F)CC3)cc3ncn(C(C)C)c23)cc1C(=O)NC(C)C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCC(CC(F)F)CC3)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCC(C(=O)CC)CC3)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)C1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4cc(C(=O)NC(C)(C)C)c(C)cc4F)n3)ccc12,HPK1,active,0.3,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCC(C(C)=O)CC3)cc3ncn(C4CC4)c23)ccc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)CC4(C)C)cc3ncn(C4CC4)c23)ccc1C,HPK1,active,0.6,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)CC4(C)C)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(F)c(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C(C)(C)O)CC3)cc3ncn(C(C)C)c23)cc1C(=O)NC(C)C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCn1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(C)=O)CC3)nc(Nc3cc(C(=O)NC(C)C)c(C)cc3F)c21,HPK1,active,0.4,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4cc(C(=O)NC(C)C)c(C)cc4F)n3)ccc12,HPK1,active,0.08,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCn1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(C)=O)CC3)nc(Nc3ccc(C)c(C(=O)NC)c3)c21,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(C)=O)CC3)nc(Nc3ccc(C)c(C(=O)NC)c3)c21,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(C)=O)CC3)cc3ncn(C4CC4)c23)ccc1Cl,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(C)=O)CC3)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCC1(CC)C(=O)N([C@H]2C[C@@H](N3CCCCC3)C2)c2cc(-c3cc4ncn(C(C)C)c4c(Nc4ccc(C)c(C(=O)NC)c4)n3)ccc21,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5C[C@H]6CC[C@@H]5C6)C3)C(=O)C43CCN(C(C)=O)CC3)cc3ncn(C4CC4)c23)ccc1C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5C[C@H]6CC[C@@H]5C6)C3)C(=O)C43CCN(C(=O)C4CCC4)CC3)cc3ncn(C4CC4)c23)ccc1C,HPK1,active,0.08,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5C[C@H]6CC[C@@H]5C6)C3)C(=O)C43CCN(C(=O)C4COC4)CC3)cc3ncn(C4CC4)c23)ccc1C,HPK1,active,0.06,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C4CC4)c23)ccc1Cl,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCOCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Oc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCOCC3)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)NC(CF)CF,HPK1,active,0.08,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)NCC(C)(F)F,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)NC1CC1,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)NCCC(F)F,HPK1,active,0.07,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCCNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.08,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCOCC3)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.07,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)NC(C)C(F)F,HPK1,active,0.05,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)NCC(F)F,HPK1,active,0.05,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)NC1(C(F)F)CC1,HPK1,active,0.3,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.4,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](NCC(C)(C)O)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](NC(C)C)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.3,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC6CCC(C5)O6)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC6C(C5)C6(F)F)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.4,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)C1=C(C)CCC(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC[C@@H](F)C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)=C1,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)NC1CCC1,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4cc(C(=O)NC5CCC5)c(C)cc4F)n3)ccc12,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4cc(C(=O)NCC(C)C)c(C)cc4F)n3)ccc12,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(C)=O)CC3)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C4COC4)CC3)cc3ncn(C(C)C)c23)cc1C(=O)NC(C)C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC[C@H](F)C5)C3)C(=O)C43CCN(C4COC4)CC3)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC[C@@H](F)C5)C3)C(=O)C43CCN(C4COC4)CC3)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC6C(C5)C6(F)F)C3)C(=O)C43CCN(C4COC4)CC3)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.7,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C4COC4)CC3)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C4(O)CCC4)CC3)cc3ncn(C4CC4)c23)ccc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C4(O)CC4)CC3)cc3ncn(C4CC4)c23)ccc1C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccc(C)c(C(=O)NC(C)C)c4)n3)ccc12,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4cc(C(=O)NC5CC5)c(C)cc4F)n3)ccc12,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
COCC1(NC(=O)c2cc(Nc3nc(-c4ccc5c(c4)N([C@H]4C[C@@H](N6CCCCC6)C4)C(=O)C54CCN(C(C)=O)CC4)cc4ncn(C(C)C)c34)c(F)cc2C)CC1,HPK1,active,0.3,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4cc(C(=O)NC(C)C)c(Cl)cc4F)n3)ccc12,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](C)NC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(C)=O)CC3)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(C)=O)CC3)cc3ncn(C4CC4)c23)cc(C)c1C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(C)=O)CC3)cc3ncn(C4CC4)c23)c(F)cc1C,HPK1,active,0.3,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccc(C)c(C(=O)NC5CC5)c4)n3)ccc12,HPK1,active,0.06,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(C)=O)CC3)cc3ncn(C4CC4)c23)c(F)cc1Cl,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1ccc(F)c(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C(C)(C)C)CC3)cc3ncn(C4CC4)c23)c1,HPK1,active,0.09,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(F)c(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C4COC4)CC3)cc3ncn(C(C)C)c23)cc1C(=O)NC(C)C,HPK1,active,0.3,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC[C@@H](F)C5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC)c(C)cc3F)c21,HPK1,active,0.3,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC[C@@H](F)C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC[C@@H](F)C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC[C@@H](F)C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.07,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCC(C(F)F)C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.3,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)nc(Nc3ccc(Cl)c(C(=O)NC)c3)c21,HPK1,active,0.05,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC[C@@H](F)C5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC)c(C)cc3F)c21,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC(C)(C)C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC(C)(C)C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)NC1CC1,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC(C)(C)C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1Cl,HPK1,active,0.07,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)cc1Cl,HPK1,active,0.09,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)NC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)cc1Cl,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)nc(Nc3ccc(C)c(C(=O)NC)c3)c21,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCOCC3)cc3ncn(C4CC4)c23)ccc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCOCC3)cc3ncn(C4CC4)c23)cc1C(N)=O,HPK1,active,0.07,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(F)c(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCOCC3)cc3ncn(C(C)C)c23)cc1C(=O)NC(C)C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCOCC3)cc3ncn(C(C)C)c23)cc1C(=O)NC(C)C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccc(C)c(C(=O)NCCO)c4)n3)ccc12,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
COCCNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(C)=O)CC3)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(F)c(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)NC1(CF)CC1,HPK1,active,0.3,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1CC(F)(F)F,HPK1,active,0.3,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)NCC(C)C,HPK1,active,0.06,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
COCCNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)NC(C)C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1C1CC1,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NC2(C(F)F)CC2)cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.07,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NC2(C(F)F)CC2)cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5C[C@H]6CC[C@@H]5C6)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.07,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
C=C(N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccc(C)c(C(=O)NC)c4)n3)ccc12)C(C)(C)O,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)C1CC(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CC[SH](C(=O)C4(C)CC4)CC3)cc3ncn(C4CC4)c23)=CC=C1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)C1CC(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CC[SH](C(=O)C4(C)CCC4)CC3)cc3ncn(C4CC4)c23)=CC=C1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)C1CC(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CC[SH](C(=O)C45CC(O)(C4)C5)CC3)cc3ncn(C(C)C)c23)=CC=C1C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C4COC4)CC3)cc3ncn(C4CC4)c23)ccc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C4(C)CC4)CC3)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C45CC(C4)C5)CC3)cc3ncn(C4CC4)c23)ccc1C,HPK1,active,0.06,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C4CCC4)CC3)cc3ncn(C4CC4)c23)ccc1C,HPK1,active,0.06,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(C)=O)CC3)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC6(C5)CC6(F)F)C3)C(=O)C43CCN(C(C)=O)CC3)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCC6(C5)CC6(F)F)C3)C(=O)C43CCN(C(C)=O)CC3)cc3ncn(C4CC4)c23)ccc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC[C@@H](F)C5)C3)C(=O)C43CCN(C(C)=O)CC3)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCC(C)(C)C5)C3)C(=O)C43CCN(C(C)=O)CC3)cc3ncn(C4CC4)c23)ccc1C,HPK1,active,0.06,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC(C)(C)CC(C)(C)C5)C3)C(=O)C43CCN(C(C)=O)CC3)cc3ncn(C4CC4)c23)ccc1C,HPK1,active,0.08,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@]3(I)C[C@H](N5CCCCC5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC4(C(F)F)CC4)c(Cl)c(F)c3F)c21,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC4(C(F)F)CC4)c(Cl)cc3F)c21,HPK1,active,0.08,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC4(CF)CC4)c(Cl)cc3F)c21,HPK1,active,0.05,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cc4c(nc3F)C(C)(C)C(=O)N4[C@H]3C[C@@](C)(N4CCCCC4)C3)nc(Nc3cc(C(=O)NC4(C(F)F)CC4)c(Cl)c(F)c3F)c21,HPK1,active,0.08,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NCC(F)F)c(Cl)c(F)c3F)c21,HPK1,active,0.08,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NCC(F)F)cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCC6(CC6)C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCC6(CC6)C5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NCC(F)F)c(Cl)c(F)c3F)c21,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NCC(F)F)c(F)c(F)c3F)c21,HPK1,active,0.04,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1cc(Nc2nc(-c3cc4c(nc3F)C(C)(C)C(=O)N4[C@H]3C[C@@](C)(N4CCCCC4)C3)cc3ncn(C(C)C)c23)c(F)c(F)c1Cl,HPK1,active,0.07,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC4(C(F)F)CC4)c(Cl)c(F)c3F)c21,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC4(C(F)F)CC4)ccc3F)c21,HPK1,active,0.02,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(F)c(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)NC1(C(F)F)CC1,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCC6CC6C5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NCC(F)F)c(Cl)c(F)c3F)c21,HPK1,active,0.05,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1cc(Nc2nc(-c3cc4c(nc3F)C(C)(C)C(=O)N4[C@H]3C[C@@](C)(N4CCC5CC5C4)C3)cc3ncn(C(C)C)c23)c(F)c(F)c1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCCC5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC4(CF)CC4)c(Cl)c(F)c3F)c21,HPK1,active,0.04,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@H](N5CCCCCC5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NCC(F)F)c(Cl)c(F)c3F)c21,HPK1,active,0.05,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CC6CC6C5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC4(C(F)F)CC4)c(Cl)c(F)c3F)c21,HPK1,active,0.3,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NC2(C(F)F)CC2)cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.08,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NC2(C(F)F)CC2)cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CC6CCC5CO6)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.06,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NC2(C(F)F)CC2)cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)CC4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@]1(N2CCCCC2)C[C@@H](N2C(=O)C(C)(C)c3ncc(-c4cc5ncn(C(C)C)c5c(Nc5cc(C(=O)NC6(C(F)F)CC6)c(C)cc5F)n4)cc32)C1,HPK1,active,0.3,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(F)c(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5C6CCC5COC6)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)NC1(C(F)F)CC1,HPK1,active,0.3,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C43CCOCC3)nc(Nc3cc(C(=O)NC4(C(F)F)CC4)c(Cl)c(F)c3F)c21,HPK1,active,0.08,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCC6(CC6)C5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC4(C(F)F)CC4)c(Cl)c(F)c3F)c21,HPK1,active,0.07,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NC2(C(F)F)CC2)cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@H](N5CCC(F)CC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NC2(C(F)F)CC2)cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCC[C@@H](F)C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NC2(C(F)F)CC2)cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCOC6(CC6)C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NC2(C(F)F)CC2)cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCC6CC5CO6)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.07,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NC2(C(F)F)CC2)cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCOC(C)(C)C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.4,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NC2(C(F)F)CC2)cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCC(F)C6(CC6)C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)NC2(CF)CC2)cc(Nc2nc(-c3cnc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)c1F,HPK1,active,0.07,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC[C@H](C(F)F)C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.09,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC[C@@H](C(F)F)C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC[C@H](C(F)F)C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@](C)(N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C4CC4)c23)cc1C(N)=O,HPK1,active,0.05,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)cc1F,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4cc(C(=O)NC(C)C)c(F)cc4F)n3)ccc12,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CN(C(C)=O)C3)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.4,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(F)c(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)NC(C)C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C4COC4)CC3)cc3ncn(C4CC4)c23)ccc1C,HPK1,active,0.08,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(F)c(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC[C@@H](F)C5)C3)C(=O)C43CCN(C4COC4)CC3)cc3ncn(C(C)C)c23)cc1C(=O)NC(C)C,HPK1,active,0.3,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC[C@@H](F)C5)C3)C(=O)C43CCN(C4COC4)CC3)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.8,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)OC)CC3)nc(Nc3ccc(C)c(C(=O)NC)c3)c21,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(S(C)(=O)=O)CC3)cc3ncn(C4CC4)c23)ccc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(S(=O)(=O)C4CC4)CC3)cc3ncn(C4CC4)c23)ccc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCC6(CC6)C5)C3)C(=O)C43CCN(C(C)=O)CC3)cc3ncn(C4CC4)c23)ccc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(C)=O)CC3)cc3ncn(C4CC4)c23)ccc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC6(C5)CC6(F)F)C3)C(=O)C43CCN(C(C)=O)CC3)nc(Nc3ccc(C)c(C(=O)NC)c3)c21,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC[C@@H](F)C5)C3)C(=O)C43CCN(C(C)=O)CC3)nc(Nc3ccc(C)c(C(=O)NC)c3)c21,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C45CC(F)(C4)C5)CC3)cc3ncn(C4CC4)c23)ccc1C,HPK1,active,0.06,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)[C@@H](C)O)CC3)cc3ncn(C4CC4)c23)ccc1C,HPK1,active,0.05,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)C1CC(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CC[SH](C(=O)[C@@H](C)O)CC3)cc3ncn(C(C)C)c23)=CC=C1C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)NC,HPK1,active,0.06,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1C(F)(F)F,HPK1,active,0.07,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](NC(=O)C(C)(C)C)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.6,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](NC(=O)C(C)(C)C)C3)C(=O)C4(C)C)cc3ncn(C)c23)cc1C(N)=O,HPK1,active,0.9,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(C)=O)CC3)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4cc(C(=O)NC(C)C)c(C)cc4F)n3)ccc12,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCOCC3)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
COCCNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)NC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1Cl,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C4CC4)c23)cc1C(N)=O,HPK1,active,0.09,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(F)c(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC[C@@H](F)C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)NC(C)C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C(F)F)C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCn1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)nc(Nc3ccc(C)c(C(=O)NC)c3)c21,HPK1,active,0.09,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCn1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)nc(Nc3cc(C(=O)NC)c(C)cc3F)c21,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(F)c(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C4COC4)CC3)cc3ncn(C(C)C)c23)cc1C(=O)NC(C)C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1ccc(F)c(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(C)=O)CC3)cc3ncn(C4CC4)c23)c1,HPK1,active,0.4,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(C)=O)CC3)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.08,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H](C)NC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(C)=O)CC3)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.3,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
COCCNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(C)=O)CC3)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](NCC(C)(C)F)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.08,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C4COC4)CC3)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(C)=O)CC3)cc3ncn(CC)c23)c(F)cc1C,HPK1,active,0.3,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C(C)C)CC3)cc3ncn(C4CC4)c23)ccc1C,HPK1,active,0.09,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C4CC4)CC3)cc3ncn(C4CC4)c23)ccc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)OC)CC3)cc3ncn(C4CC4)c23)ccc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C45CC(C4)C5)CC3)cc3ncn(C4CC4)c23)ccc1Cl,HPK1,active,0.07,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCC(C)(C)C5)C3)C(=O)C4(C)C)cc3ncn(C4CC4)c23)ccc1C,HPK1,active,0.07,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC[C@@H](O)C5)C3)C(=O)C4(C)C)cc3ncn(C4CC4)c23)cc1C(N)=O,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC[C@H](O)C5)C3)C(=O)C4(C)C)cc3ncn(C4CC4)c23)cc1C(N)=O,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Oc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C4CC4)c23)ccc1C,HPK1,active,0.6,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Oc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C4CC4)c23)cc1C(N)=O,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCOCC3)cc3ncn(C(C)C)c23)cc1C(=O)NC1(C(F)F)CC1,HPK1,active,0.08,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)N[C@H](C)CF,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)N[C@@H](C)CF,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)NC1(C(F)F)CC1,HPK1,active,0.07,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCOCC3)cc3ncn(C(C)C)c23)cc1C(=O)NC1CCC1,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC[C@@H](F)C5)C3)C(=O)C4(C)C)cc3ncn(C4CC4)c23)cc1C(N)=O,HPK1,active,0.04,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCOC(C)(C)C5)C3)C(=O)C4(C)C)cc3ncn(C4CC4)c23)cc1C(N)=O,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N[C@@H]5CCOC[C@H]5C)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N[C@@H]5CCOC[C@@H]5C)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.09,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](NC(C)C)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5C6COCC5C6)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5C6CCC5COC6)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)cc1C,HPK1,active,0.08,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5C6COCC5C6)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC[C@H](F)C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.2,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)C1=C(C)CCC(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)=C1,HPK1,active,0.1,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ccc1C,HPK1,active,0.08,ic50,WO2020092621A1_Original_document_20201118034207, not Ki or Kd; not used in NCI fingerprint analysis
[2H]C1([2H])N([C@H]2C[C@@H](N3C(=O)C(C)(C)c4ccc(-c5cc6ncn(C(C)C)c6c(Nc6ccncc6F)n5)cc43)C2)C([2H])([2H])C([2H])([2H])C([2H])([2H])C1([2H])[2H],HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C4(C)CCO4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5C[C@@H](C)[C@@H](C)C5)C3)C(=O)C43CCN(C(=O)C(C)(C)CO)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.05,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5C[C@@H](C)[C@@H](C)C5)C3)C(=O)C43CCN(C(=O)[C@@H]4CCCO4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5C[C@@H](C)[C@@H](C)C5)C3)C(=O)C43CCN(C(=O)C4(C)COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC6CC(C6)C5)C3)C(=O)C43CCN(C(=O)C4(C)COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5C6CCC5COC6)C3)C(=O)C43CCN(C(=O)C4(C)COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.5,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC6(CC6)C5)C3)C(=O)C43CCN(C(=O)C4(C)COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.5,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)C(C)(C)O)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.4,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C(C)(C)O)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.6,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)[C@H](C)O)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.5,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C4(C)CCOCC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.6,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)[C@@H]4CCCO4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)[C@H]4CCCO4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)C4(C)CCOC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)[C@H]4CCOC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)[C@@H]4CCOC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C4(C)CC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.5,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)C4(C)CCOCC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)C4CCCOC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)C4CCCCO4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.09,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)C4CCOCC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C4CCO4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCC(C)(C)C3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.4,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3C[C@@H](C)[C@@H](C)C3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCC[C@@H](C)C3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.6,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4cc(C)ncc4F)n3)ccc12,HPK1,active,1.1,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCC6(CC6)C5)C3)C(=O)C43CCN(C(=O)[C@H](C)O)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCC6(CC6)C5)C3)C(=O)C43CCN(C(=O)C4(C)COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](O)C(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCC(C)(C)C3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](O)C(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.4,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5C[C@H]6CC[C@H]6C5)C3)C(=O)C43CCN(C(=O)[C@H](C)O)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.07,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5C[C@H]6CC[C@H]6C5)C3)C(=O)C43CCN(C(=O)C(C)(C)CO)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.08,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5C[C@H]6CC[C@H]6C5)C3)C(=O)C43CCN(C(=O)[C@H]4CCCO4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.08,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5C[C@H]6CC[C@H]6C5)C3)C(=O)C43CCN(C(=O)C4(C)COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C(C)(C)CO)CC3)nc(Nc3ccnc(F)c3F)c21,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)O)nc(Nc3ccnc(F)c3F)c21,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC(C)(C)C5)C3)C(=O)C4(C)C)nc(Nc3cc(CO)ncc3F)c21,HPK1,active,3.1,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4cc(N(C)C)ncc4F)n3)ccc12,HPK1,active,1.6,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4cc(CO)ncc4F)n3)ccc12,HPK1,active,1,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(F)c(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(C)=O)CC3)cc3ncn(C(C)C)c23)cn1,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C4COC4)CC3)nc(Nc3cc(F)ncc3F)c21,HPK1,active,1.9,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C4COC4)CC3)nc(Nc3ccnc(F)c3F)c21,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H](C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C4COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H](C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C4COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.5,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CCn1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C4COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.7,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)CN[C@H]1C[C@@H](N2C(=O)C(C)(C)c3ccc(-c4cc5ncn(C(C)C)c5c(Nc5ccncc5F)n4)cc32)C1,HPK1,active,1.7,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCC(C)(C)C5)C3)C(=O)C4(C)C)nc(Nc3ccncc3F)c21,HPK1,active,0.8,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCC(C)(C)C5)C3)C(=O)C4(C)C)nc(Nc3ccc(=O)[nH]c3)c21,HPK1,active,0.1,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCC(C)(F)C5)C3)C(=O)C43CCN(C4COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.4,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC[C@H](F)C5)C3)C(=O)C43CCN(C4COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.4,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)C4(C)COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.4,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4cc(C(=O)N(C)C)cnc4F)n3)ccc12,HPK1,active,6.6,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CCn1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C(C)C)CC3)nc(Nc3ccc(F)nc3F)c21,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H](C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(C)=O)CC3)nc(Nc3cccnc3F)c21,HPK1,active,0.7,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCOCC3)nc(Nc3cccnc3F)c21,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccc(F)nc4F)n3)ccc12,HPK1,active,0.1,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ncc(F)cc4F)n3)ccc12,HPK1,active,5.6,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccc(F)nc4F)n3)ccc12,HPK1,active,0.1,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.5,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](NCC(C)(C)F)C3)C(=O)C4(C)C)nc(Nc3ccncc3F)c21,HPK1,active,1.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC6CCC(C6)C5)C3)C(=O)C4(C)C)nc(Nc3ccncc3F)c21,HPK1,active,0.05,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC6CC6C5)C3)C(=O)C4(C)C)nc(Nc3ccncc3F)c21,HPK1,active,0.8,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC6C(C5)C6(C)C)C3)C(=O)C4(C)C)nc(Nc3ccncc3F)c21,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCCC5)C3)C(=O)C4(C)C)nc(Nc3ccncc3F)c21,HPK1,active,0.09,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5C[C@@H](C)[C@@H](C)C5)C3)C(=O)C4(C)C)nc(Nc3ccncc3F)c21,HPK1,active,0.4,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)cn1,HPK1,active,1.5,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](NCC(C)(C)O)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)cn1,HPK1,active,2.1,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC6CCC(C6)C5)C3)C(=O)C43CCN(C(=O)C4CCO4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.04,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC6CCC(C6)C5)C3)C(=O)C43CCN(C(=O)C4COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.07,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CCC1(C(=O)N2CCC3(CC2)C(=O)N([C@H]2C[C@@H](N4CCCCC4)C2)c2cc(-c4cc5ncn(C(C)C)c5c(Nc5ccncc5F)n4)ccc23)COC1,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C4(C(C)C)COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.08,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@H]1C[C@@H](C(=O)N2CCC3(CC2)C(=O)N([C@H]2C[C@@H](N4CCCCC4)C2)c2cc(-c4cc5ncn(C(C)C)c5c(Nc5ccncc5F)n4)ccc23)C1,HPK1,active,0.5,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)C4(CO)CC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.4,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C4(CO)CC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)C4CCO4)CC3)cc3ncn(C(C)C)c23)c(F)cn1,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C4(F)CC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.5,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C4(F)CCC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.5,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CCn1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C(C)C)CC3)nc(Nc3ccncc3F)c21,HPK1,active,1.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@H](C)C(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H](C)C(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.5,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)c4cnco4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.4,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)C4(C)COC4)CC3)nc(Nc3ccc(F)nc3F)c21,HPK1,active,0.06,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)C(C)(C)CO)CC3)nc(Nc3ccc(F)nc3F)c21,HPK1,active,0.08,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CCC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.4,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.5,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C(C)(C)C)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C4COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.5,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCC(C)(C)C3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4cc(C)ncc4F)n3)ccc12,HPK1,active,0.4,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC[C@@H](C)C5)C3)C(=O)C43CCN(C4COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,1.6,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC[C@@H](F)C5)C3)C(=O)C43CCN(C4COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,1.1,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCC(C)(C)C5)C3)C(=O)C43CCN(C4COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC[C@H](C)C5)C3)C(=O)C43CCN(C4COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,1.1,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(F)CC5)C3)C(=O)C43CCN(C4COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,1.1,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC[C@H](C)C5)C3)C(=O)C43CCN(C4COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.6,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5C[C@H](O)C(C)(C)C5)C3)C(=O)C43CCN(C4COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.6,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCC6(CC6)C5)C3)C(=O)C43CCN(C(=O)C(C)(C)CO)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCC6(CC6)C5)C3)C(=O)C43CCN(C(=O)CO)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CCn1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC(C)(C)C5)C3)C(=O)C43CCN(C4COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.8,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N(C1CC(N3CCCC4(CC4)C3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3C4CCCC3CC4)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.1,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCC[C@@H]3C)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.7,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCC4CC4C3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.4,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCC4(CCC4)C3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)[C@H]4CC[C@@H](C)O4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.05,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)[C@@H]4OCC[C@@H]4C)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.1,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)[C@H]4OCC[C@H]4C)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)[C@@]4(C)CCCO4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)[C@@H]4CCO4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)[C@H]4CCO4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)[C@@]4(C)O)nc(Nc3ccncc3F)c21,HPK1,active,2.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cnc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)cc1C(=O)NC1(CF)CC1,HPK1,active,6,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)ncc1C,HPK1,active,9.6,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CC4CCC3CC4)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC[C@H](C)C5)C3)C(=O)C4(C)C)nc(Nc3ccncc3F)c21,HPK1,active,1.1,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC[C@H](C)C5)C3)C(=O)C4(C)C)nc(Nc3ccncc3F)c21,HPK1,active,0.9,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5C6COCC5C6)C3)C(=O)C4(C)C)nc(Nc3ccncc3F)c21,HPK1,active,2.1,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C4(C)C)nc(Nc3ccncc3F)c21,HPK1,active,0.6,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C4(C)COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.4,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
COC1(C(=O)N2CCC3(CC2)C(=O)N([C@H]2C[C@@H](N4CCCCC4)C2)c2cc(-c4cc5ncn(C(C)C)c5c(Nc5ccncc5F)n4)ccc23)CC1,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
COC(C)(C)C(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.4,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C4COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C(C)(C)C#N)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
COCC(C)(C)C(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C(C)(C)CO)CC3)cc3ncn(C(C)C)c23)c(F)cn1,HPK1,active,0.8,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)C(C)(C)CO)CC3)cc3ncn(C(C)C)c23)c(F)cn1,HPK1,active,0.6,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)C4(C)COC4)CC3)nc(Nc3cc(Cl)ncc3F)c21,HPK1,active,1,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C4(C)COC4)CC3)cc3ncn(C(C)C)c23)c(F)cn1,HPK1,active,0.6,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC6CCC(C6)C5)C3)C(=O)C43CCN(C(=O)CO)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.07,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)[C@@H]4CC[C@H](C)O4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.1,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)[C@]4(C)CCCO4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)[C@]4(C)O)nc(Nc3ccncc3F)c21,HPK1,active,1.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCC5)C3)C(=O)C4(C)C)nc(Nc3ccncc3F)c21,HPK1,active,3.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CC4CC4(C)C3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CC4CCC(C4)C3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.1,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CC4CC4C3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,1.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
COC(C)(C)CN(C)[C@H]1C[C@@H](N2C(=O)C3(CCN(C(C)=O)CC3)c3ccc(-c4cc5ncn(C(C)C)c5c(Nc5ccncc5F)n4)cc32)C1,HPK1,active,4.5,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCC4(CC4)C3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.8,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC(C)(C)C5)C3)C(=O)C43CCN(C4COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.8,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3C[C@H]4CC[C@H]4C3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.1,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CCn1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C(C)(C)C)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.8,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CCC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(CC)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,2.6,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CC4CCC(C4)C3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4cc(C)ncc4F)n3)ccc12,HPK1,active,0.1,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5C[C@@H]6CC[C@H]5C6)C3)C(=O)C43CCN(C(=O)C4(C)COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)c4nccs4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.1,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)c4cnnn4C)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.4,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)c4ncon4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.4,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)c4ncco4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.4,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@H]1C[C@H](C(=O)N2CCC3(CC2)C(=O)N([C@H]2C[C@@H](N4CCC(C)(C)C4)C2)c2cc(-c4cc5ncn(C(C)C)c5c(Nc5ccncc5F)n4)ccc23)C1,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@H]1C[C@@H](C(=O)N2CCC3(CC2)C(=O)N([C@H]2C[C@@H](N4CCC(C)(C)C4)C2)c2cc(-c4cc5ncn(C(C)C)c5c(Nc5ccncc5F)n4)ccc23)C1,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)c4ccon4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)c4cocn4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CCn1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C45CC(F)(C4)C5)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C4CC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C4(C#N)CC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C(C)(C)CF)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.5,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC6CCC(C6)C5)C3)C(=O)C43CCN(C(=O)C(C)(C)CO)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.07,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC6CCC(C6)C5)C3)C(=O)C43CCN(C(=O)[C@H](C)O)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.1,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC6CCC(C6)C5)C3)C(=O)C43CCN(C(=O)C4(C)COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.1,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)[C@H](C)O)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.5,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)[C@@H](O)C(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCC(C)(C)C3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)[C@H](O)C(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCC(C)(C)C3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H](O)C(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCC(C)(C)C3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.4,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H](O)C(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.4,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)[C@H]4CCC[C@H]4O)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)C4CCO4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
COC1(C(=O)N2CCC3(CC2)C(=O)N([C@H]2C[C@@H](N4CCCCC4)C2)c2cc(-c4cc5ncn(C(C)C)c5c(Nc5ccncc5F)n4)ccc23)CCC1,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C(C)(C)CO)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4cc5ccncc5cc4F)n3)ccc12,HPK1,active,0.4,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1ccc(F)c(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)n1,HPK1,active,1.4,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)[C@H](C)O)CC3)nc(Nc3ccnc(F)c3F)c21,HPK1,active,0.1,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C4(C)COC4)CC3)nc(Nc3ccc(F)nc3F)c21,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)nc(Nc3ccnc(F)c3F)c21,HPK1,active,2.5,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)nc(Nc3ccnc(F)c3F)c21,HPK1,active,0.3,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C4COC4)CC3)nc(Nc3ccnc(F)c3F)c21,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(Nc2nc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)cc3ncn(C(C)C)c23)c(F)cn1,HPK1,active,8.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC[C@@](C)(F)C5)C3)C(=O)C43CCN(C4COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.6,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CCn1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC(C)(C)C5)C3)C(=O)C4(C)C)nc(Nc3ccncc3F)c21,HPK1,active,2.5,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCC(C)(C)C5)C3)C(=O)C4(C)C)nc(Nc3ccc(=O)n(C)c3)c21,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)C4CCO4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.7,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)C4COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.5,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C4COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.4,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5C[C@@H]6CC[C@H]5C6)C3)C(=O)C4(C)C)nc(Nc3ccncc3F)c21,HPK1,active,0.7,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)nc(Nc3c(F)cncc3F)c21,HPK1,active,0.7,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC6CCC5CC6)C3)C(=O)C4(C)C)nc(Nc3ccncc3F)c21,HPK1,active,0.7,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC6(CC6)C5)C3)C(=O)C4(C)C)nc(Nc3ccncc3F)c21,HPK1,active,0.8,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)O)nc(Nc3ccncc3F)c21,HPK1,active,0.9,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](NCC(C)(C)O)C3)C(=O)C4(C)C)nc(Nc3ccncc3F)c21,HPK1,active,1.6,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5C6CCC5COC6)C3)C(=O)C43CCN(C4COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.5,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC(F)C6(CC6)C5)C3)C(=O)C43CCN(C4COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.5,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C(F)F)C5)C3)C(=O)C43CCN(C4COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,1.5,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC[C@H](F)C5)C3)C(=O)C43CCN(C4COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.6,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC(C)(C)C[C@H]5CO)C3)C(=O)C43CCN(C4COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.6,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC(C)(C)C[C@@H]5CO)C3)C(=O)C43CCN(C4COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,1.4,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CC(O)C(C)(C)C5)C3)C(=O)C43CCN(C4COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CC4CCC(C3)O4)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)N1CCC2(CC1)C(=O)N([C@H]1C[C@@H](N3CCCCC3)C1)c1cc(-c3cc4ncn(C(C)C)c4c(Nc4ccncc4F)n3)ccc12,HPK1,active,0.6,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C43CCN(C(=O)C45CC(F)(C4)C5)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.1,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)CC4COC4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.4,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)C4(C)CCCO4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3ccc4c(c3)N([C@H]3C[C@@H](N5CCC(C)(C)C5)C3)C(=O)C43CCN(C(=O)C4(C)CCO4)CC3)nc(Nc3ccncc3F)c21,HPK1,active,0.1,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(F)c3c(c2C)C(=Cc2cc4cnccc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.27,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)C(=Cc2c[nH]c4ccccc24)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.42,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)C(=Cc2ncc[nH]2)C(=O)N3)cnc2c1NCC1(CC1)O2,HPK1,active,2.13,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)C(=Cc2cn[nH]c2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.26,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1n[nH]cc1C=C1C(=O)Nc2ccc(-c3cnc4c(c3C)NCCO4)cc21,HPK1,active,0.32,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3c(c2C)NCCO3)cc2c1NC(=O)C2=Cc1cn[nH]c1,HPK1,active,4.33,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(Cl)c3c(c2)C(=Cc2cn[nH]c2)C(=O)N3)cnc2c1NCCO2,HPK1,active,6.9,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(F)c3c(c2C)C(=Cc2cn[nH]c2)C(=O)N3)cnc2c1NCCO2,HPK1,active,1.03,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(F)c3c(c2C)C(=Cc2cc4ncccc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.31,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(F)c3c(c2C)C(=Cc2cc4ccncc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.41,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)C(=Cc2cc4ccccc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.05,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)C(=Cc2cc4cccnc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,1.1,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)C(=Cc2cc4cnccc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.06,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)C(=Cc2nc4ccccc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.28,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)C(=Cc2cc4ncccc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.05,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)C(=Cc2cc4ccncc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.11,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cnc3c(c2)C(=Cc2cc4ccccc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,1.24,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(F)c3c(c2C)C(=Cc2cc4ccccc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.51,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(F)c3c(c2)C(=Cc2cc4ccccc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.16,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc3c(cc2F)NC(=O)C3=Cc2cc3ccccc3[nH]2)cnc2c1NCCO2,HPK1,active,0.16,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(F)c3c(c2)C(=Cc2cc4cnccc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.1,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc3c(cc2Cl)NC(=O)C3=Cc2cc3ccccc3[nH]2)cnc2c1NCCO2,HPK1,active,0.19,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc3c(cc2F)NC(=O)C3=Cc2cc3cnccc3[nH]2)cnc2c1NCCO2,HPK1,active,0.16,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cnc3c(c2)C(=Cc2cc4cnccc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,1.13,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc3c(cc2Cl)NC(=O)C3=Cc2cc3cnccc3[nH]2)cnc2c1NCCO2,HPK1,active,0.16,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(F)c3c(c2)C(=Cc2cc4ncccc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.05,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(F)c3c(c2)C(=Cc2cc4ccncc4[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.17,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc3c(cc2F)NC(=O)C3=Cc2cc3ncccc3[nH]2)cnc2c1NCCO2,HPK1,active,0.05,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc3c(cc2F)NC(=O)C3=Cc2cc3ccncc3[nH]2)cnc2c1NCCO2,HPK1,active,0.13,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(cc1-c1cnc3c(c1)NCCO3)C(=Cc1cc3cnccc3[nH]1)C(=O)N2,HPK1,active,5.73,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cnc3c(c2)NCCO3)cc(F)c2c1C(=Cc1cc3cnccc3[nH]1)C(=O)N2,HPK1,active,9.3,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(cc1-c1cnc3c(c1C)NCCO3)C(=Cc1cc3cnccc3[nH]1)C(=O)N2,HPK1,active,0.07,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)C(=Cc2cc4cnccc4[nH]2)C(=O)N3)ccc2c1NC(=O)CO2,HPK1,active,7.03,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(cc1-c1cnc3c(c1C)NCCO3)C(=Cc1cc3ncccc3[nH]1)C(=O)N2,HPK1,active,0.11,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(cc1-c1cnc3c(c1C)NCCO3)C(=Cc1cc3ccncc3[nH]1)C(=O)N2,HPK1,active,0.69,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
CCC(=C1C(=O)Nc2ccc(-c3cnc4c(c3C)NCCO4)cc21)c1cnc[nH]1,HPK1,active,1,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(F)c3c(c2)C(=Cc2cnc(C4CC4)[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.05,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)C(=Cc2cnc(C4CC4)[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.13,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)C(=Cc2ncc[nH]2)C(=O)N3)cnc2c1NC(=O)C1(CC1)O2,HPK1,active,5.66,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)C(=Cc2cnc[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.97,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)C(=Cc2ccc[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.05,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c[nH]c(C=C2C(=O)Nc3ccc(-c4cnc5c(c4C)NCCO5)cc32)c1,HPK1,active,0.05,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)C(=Cc2cnn[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,1.64,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(F)c3c(c2)C(=Cc2ccc[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.05,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c[nH]c(C=C2C(=O)Nc3c(F)cc(-c4cnc5c(c4C)NCCO5)cc32)c1,HPK1,active,0.05,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c[nH]c(C=C2C(=O)Nc3c(C)cc(-c4cnc5c(c4C)NCCO5)cc32)c1,HPK1,active,2.93,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(Cl)c3c(c2)C(=Cc2ccc[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,1.98,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c[nH]c(C=C2C(=O)Nc3c(Cl)cc(-c4cnc5c(c4C)NCCO5)cc32)c1,HPK1,active,2.61,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)C(=Cc2cc(C#N)c[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.07,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)C(=Cc2cc(Br)c[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.16,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)C(=Cc2cccs2)C(=O)N3)cnc2c1NCCO2,HPK1,active,1.88,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccc3c(c2)C(=Cc2ccns2)C(=O)N3)cnc2c1NCCO2,HPK1,active,3.02,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C=C2C(=O)Nc3ccc(-c4cnc5c(c4C)NCCO5)cc32)[nH]1,HPK1,active,0.05,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN(CC)CCNC(=O)c1c(C)[nH]c(C=C2C(=O)Nc3ccc(-c4cnc5c(c4C)NCCO5)cc32)c1C,HPK1,active,0.05,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ncc(C=C2C(=O)Nc3ccc(-c4cnc5c(c4C)NCCO5)cc32)[nH]1,HPK1,active,0.07,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(F)c3c(c2C)C(=Cc2ccc[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.29,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(=C1C(=O)Nc2ccc(-c3cnc4c(c3C)NCCO4)cc21)c1cnc[nH]1,HPK1,active,0.44,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c[nH]c(C=C2C(=O)Nc3c(F)cc(-c4cnc5c(c4C)NCCO5)c(C)c32)c1,HPK1,active,0.51,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(F)c3c(c2C)C(=Cc2cc(C#N)c[nH]2)C(=O)N3)cnc2c1NCCO2,HPK1,active,0.67,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ncc(C=C2C(=O)Nc3c(F)cc(-c4cnc5c(c4C)NCCO5)cc32)[nH]1,HPK1,active,0.22,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ncc(C=C2C(=O)Nc3cc(F)c(-c4cnc5c(c4C)NCCO5)cc32)[nH]1,HPK1,active,0.18,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ncc(C=C2C(=O)Nc3cc(Cl)c(-c4cnc5c(c4C)NCCO5)cc32)[nH]1,HPK1,active,0.29,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1nc(C)c(C=C2C(=O)Nc3ccc(-c4cnc5c(c4C)NCCO5)cc32)[nH]1,HPK1,active,0.12,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ncc(C=C2C(=O)Nc3c(F)cc(-c4cnc5c(c4)NCCO5)c(C)c32)[nH]1,HPK1,active,7.43,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ncc(C=C2C(=O)Nc3cc(C)c(-c4cnc5c(c4C)NCCO5)cc32)[nH]1,HPK1,active,0.19,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ncc(C=C2C(=O)Nc3c(F)cc(-c4cnc5c(c4C)NCCO5)c(C)c32)[nH]1,HPK1,active,0.15,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ncc(C=C2C(=O)Nc3ccc(-c4ccc5c(c4C)NCCO5)cc32)[nH]1,HPK1,active,1.95,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc([C@@H](O)C5CN(C)C5)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,6.7,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(NC(=O)CN6CCCC6)cc5)c4c3)cc2)CC1,HPK1,active,2.4,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc([C@H](O)C5CN(C)C5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,6.2,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN[C@@H]1CCN(C(=O)c2ccc(-c3c[nH]c4ncc(-c5ccc(N6CCN(C)CC6)c(C)c5)cc34)cc2)C1,HPK1,active,8.3,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN[C@H]1CCN(C(=O)c2ccc(-c3c[nH]c4ncc(-c5ccc(N6CCN(C)CC6)c(C)c5)cc34)cc2)C1,HPK1,active,7.1,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(O)C5CCN(C)C5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,4.5,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc5c(c4)CCN(C)C5=O)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,8.8,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC(O)C5)cc4)c3c2)cc(C)c1N1CCN(CCO)CC1,HPK1,active,8.6,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(O)C5CN(C)C5)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,4.7,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)C5CN(C)C5)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,6.2,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(O)C5CNC5)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,5.9,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)C5CNC5)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,8.4,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC(N(C)C)C5)cc4)c3c2)cc(C)c1N1CCN(CCO)CC1,HPK1,active,8.5,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)CC5CN(C)C5)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,9.5,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(OCCCCN)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,9.8,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC6(COC6)C5)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,1.6,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC(O)C5)cc4)c3n2)cc(OC)c1N1CCN(C2CCN(C)CC2)CC1,HPK1,active,6,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)CCN(C)C)cc4)c3n2)cc(C)c1N1CCN(C)CC1,HPK1,active,9.6,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)CCN(C)C)cc4)c3n2)cc(OC)c1N1CCN(C)CC1,HPK1,active,7.2,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3n2)cc(C)c1N1CCN(CCO)CC1,HPK1,active,8.3,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC(O)C5)cc4)c3n2)cc(C)c1N1CCN(C2CCN(C)CC2)CC1,HPK1,active,9.2,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC(N(C)C)C5)cc4)c3c2)cc(C)c1N1CCN(C2CCN(C)CC2)CC1,HPK1,active,4.8,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(OCCCN)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,5.3,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC(N(C)C)C5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,9.4,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC6(COC6)C5)cc4)c3c2)cc(C)c1CN1CCN(CC2CC2)CC1,HPK1,active,5.8,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)CCCCO)cc5)c4c3)cc2)CC1,HPK1,active,3,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)CCN(C)C)cc4)c3n2)cc(C)c1N1CCN(C2CCN(C)CC2)CC1,HPK1,active,6,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)CCCN(C)C)cc4)c3n2)cc(C)c1N1CCN(C)CC1,HPK1,active,9.6,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(OC5CCNCC5)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,6.2,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(OC5CCNC5)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,7.3,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc(C)c1CN1CCN(C)CC1,HPK1,active,6.7,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(Cc2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2)CC1,HPK1,active,8.5,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(CCO)CC5)cc4)cc23)cc1,HPK1,active,5,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(CCc2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2)CC1,HPK1,active,4,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(N2CCN(c3ccc(-c4cnc5[nH]cc(-c6ccc(C(=O)N(C)C)cc6)c5c4)cc3)CC2)CC1,HPK1,active,3.2,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(CC6CC6)CC5)cc4)cc23)cc1,HPK1,active,5.7,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2C#N)CC1,HPK1,active,5.2,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,2.2,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(NS(=O)(=O)C5CC5)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,7.2,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CCN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4cc(C)c(N5CCN(C)CC5)c(C)c4)cc23)cc1,HPK1,active,2.3,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)CCN(C)C)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,1.4,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COCCCN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4cc(C)c(N5CCN(C)CC5)c(C)c4)cc23)cc1,HPK1,active,2,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,1.9,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COCCCN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)c(C)c4)cc23)cc1,HPK1,active,2.1,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC6(COC6)C5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,2.1,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,1.3,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(OCCN)cc5)c4c3)cc2)CC1,HPK1,active,1.4,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(OCCC(=O)N(C)C)cc5)c4c3)cc2)CC1,HPK1,active,5.7,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(OCC(=O)N(C)C)cc5)c4c3)cc2)CC1,HPK1,active,7.7,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCOc1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,active,5,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(OCCCN)cc5)c4c3)cc2)CC1,HPK1,active,1.6,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCNC(=O)Nc1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,medium,168,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)N(C)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,active,9.6,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5cnc(C(=O)N(C)C)nc5)c4c3)cc2)CC1,HPK1,active,7.5,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5c(F)cc(C(=O)N(C)C)cc5F)c4c3)cc2)CC1,HPK1,medium,161,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COCCN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,active,2.1,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COCCCN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,active,35,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C6CC6)cc5)c4c3)cc2)CC1,HPK1,active,86,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CCN(CC)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,medium,178,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(CCO)CC5)cc4)nc23)cc1,HPK1,active,6.7,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(N2CCN(c3ccc(-c4cnc5[nH]cc(-c6ccc(C(=O)N(C)C)cc6)c5n4)cc3)CC2)CC1,HPK1,active,7.1,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(CC6CC6)CC5)cc4)nc23)cc1,HPK1,active,7.3,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CCN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4cc(C)c(N5CCN(C)CC5)c(C)c4)nc23)cc1,HPK1,active,31,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)O)cc4)c3n2)cc(C)c1N1CCN(C)CC1,HPK1,active,7.6,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3n2)cc(C)c1N1CCN(C)CC1,HPK1,active,28,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3n2)ccc1N1CCN(C)CC1,HPK1,active,68,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4n3)cc2Cl)CC1,HPK1,active,5.1,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(OCCN)nc5)c4n3)cc2)CC1,HPK1,active,5.6,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(=O)n(CCN)c5)c4n3)cc2)CC1,HPK1,active,5.3,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(OCC(=O)N(C)C)cc5)c4n3)cc2)CC1,HPK1,active,5.6,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)Nc1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)nc23)cc1,HPK1,active,7.4,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(OCCN)cc5)c4n3)cc2)CC1,HPK1,active,62,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCOc1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)nc23)cc1,HPK1,active,6,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COCCN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)nc23)cc1,HPK1,active,8.2,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C6CC6)cc5)c4n3)cc2)CC1,HPK1,active,5.6,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)nc5)c4n3)cc2)CC1,HPK1,active,9.8,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CC(O)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,active,8.9,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2C)ccc1N1CCN(C)CC1,HPK1,medium,117,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(CCc2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC7(COC7)C6)cc5)c4n3)cc2)CC1,HPK1,active,7.4,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(CCc2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4n3)cc2)CC1,HPK1,active,7.6,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(CCc2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C6CC6)cc5)c4c3)cc2)CC1,HPK1,active,5.8,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(CCc2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC7(COC7)C6)cc5)c4c3)cc2)CC1,HPK1,medium,164,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(-c2c[nH]c3ncc(-c4cnn(C5CCN(C)CC5)c4)cc23)cc1,HPK1,medium,129,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(-c2c[nH]c3ncc(-c4cnn(C)c4)cc23)cc1,HPK1,active,5.9,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC(N(C)C)C6)cc5)c4n3)cc2)CC1,HPK1,active,5.5,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CCC(N(C)C)CC6)cc5)c4n3)cc2)CC1,HPK1,active,7.6,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC7(COC7)C6)cc5)c4n3)cc2)CC1,HPK1,active,4,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCCN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)nc23)cc1,HPK1,active,7.5,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)nc23)cc1,HPK1,active,6.8,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCNC(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)nc23)cc1,HPK1,active,9.2,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)nc23)c(F)c1,HPK1,active,7.6,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(NC(=O)CCCN6CCCC6)cc5)c4c3)cc2)CC1,HPK1,active,8.6,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)CCCN6CCCC6)cc5)c4c3)cc2)CC1,HPK1,active,95,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CCN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,medium,109,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COCCOC1CN(C(=O)c2ccc(-c3c[nH]c4ncc(-c5ccc(N6CCN(C)CC6)cc5)cc34)cc2)C1,HPK1,active,7,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)CCCN6CCCCC6)cc5)c4c3)cc2)CC1,HPK1,active,5.2,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CCC(N(C)C)CC6)cc5)c4c3)cc2)CC1,HPK1,medium,144,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC7(CCOCC7)C6)cc5)c4c3)cc2)CC1,HPK1,active,8.9,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,active,79,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC7(COC7)C6)cc5)c4c3)cc2)CC1,HPK1,active,66,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CCN(CC7CC7)CC6)cc5)c4c3)cc2)CC1,HPK1,active,50,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC(O)C6)cc5)c4c3)cc2)CC1,HPK1,active,55,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)NCC6CCCO6)cc5)c4c3)cc2)CC1,HPK1,active,6,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CCC(O)CC6)cc5)c4c3)cc2)CC1,HPK1,active,6.3,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COCCNC(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,active,5.7,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCNC(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,medium,110,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)NCCCN6CCCCC6)cc5)c4c3)cc2)CC1,HPK1,active,8.4,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCCN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,active,5,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(C(=O)c2ccc(-c3c[nH]c4ncc(-c5ccc(N6CCN(C)CC6)cc5)cc34)cc2)CC1,HPK1,active,44,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CCC6)cc5)c4c3)cc2)CC1,HPK1,medium,123,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CCCC6)cc5)c4c3)cc2)CC1,HPK1,medium,123,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,active,5.6,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CCOCC6)cc5)c4c3)cc2)CC1,HPK1,active,5.9,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)c(C)c4)cc23)cc1,HPK1,active,44,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)c1ccc(-c2c[nH]c3c2C=C(c2ccc(N4CCN(C)CC4)cc2)CN3)cc1,HPK1,active,6.6,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COC1CN(Cc2ccc(-c3c[nH]c4ncc(-c5ccc(N6CCN(C)CC6)cc5)cc34)cc2)C1,HPK1,active,5.2,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(Cc2ccc(-c3c[nH]c4ncc(-c5ccc(N6CCN(C)CC6)cc5)cc34)cc2)CC1,HPK1,medium,103,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5F)c4c3)cc2)CC1,HPK1,active,92,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)nc5)c4c3)cc2)CC1,HPK1,active,7.8,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)Cc1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,active,6.4,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cn1,HPK1,active,7.3,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccncc5)c4c3)cc2)CC1,HPK1,active,7.8,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(N)cc5)c4c3)cc2)CC1,HPK1,medium,113,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2)CC1,HPK1,active,2.4,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,active,98,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN[C@H]1CCN(C(=O)c2ccc(-c3c[nH]c4ncc(-c5cc6c(c(OC)c5)CCN(C)C6)nc34)cc2)C1,HPK1,active,7,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(N2CCc3cc(-c4cnc5[nH]cc(-c6ccc(C(=O)C7CN(C)C7)cc6)c5c4)ccc3C2)CC1,HPK1,active,8.2,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc2c1CCN(C)C2,HPK1,active,7.3,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3P(C)(C)=O)n1)CN(C)CC2(C)C,HPK1,active,5,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3P(C)(C)=O)n1)CNCC2,HPK1,active,5,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3P(C)(C)=O)n1)CNCC2(C)C,HPK1,active,5,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
CCc1cnc(Nc2cc3c(cc2OC)CCN(C)C3)nc1Nc1ccccc1P(C)(C)=O,HPK1,active,5,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
C=Cc1cnc(Nc2cc3c(cc2OC)CCN(C)C3)nc1Nc1ccccc1P(C)(C)=O,HPK1,active,5,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3P(C)(C)=O)n1)CCNC2,HPK1,active,5,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1ccccc1Nc1nc(Nc2cc3c(cc2OC)CCN(C)C3)ncc1Cl,HPK1,active,5,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3S(=O)(=O)N(C)C)n1)CN(C)CC2,HPK1,active,5,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n1)CN(C)CC2,HPK1,active,5,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3P(C)(C)=O)n1)C(C)N(C)CC2,HPK1,active,5,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C(F)(F)F)c(Nc3ccccc3P(C)(C)=O)n1)CN(C)CC2,HPK1,active,5,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCc2c(Br)cc(Nc3ncc(Cl)c(Nc4ccccc4P(C)(C)=O)n3)cc2C1,HPK1,active,5,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(OC)c(Nc3ccccc3P(C)(C)=O)n1)CN(C)CC2,HPK1,active,5,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Br)c(Nc3ccccc3P(C)(C)=O)n1)CN(C)CC2,HPK1,active,5,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCc2cc(Nc3ncc(Cl)c(Nc4ccccc4P(C)(C)=O)n3)c(Cl)cc2C1,HPK1,active,5,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
CCP(=O)(CC)c1ccccc1Nc1nc(Nc2cc3c(cc2Cl)CCN(C)C3)ncc1Cl,HPK1,active,5,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
CCP(=O)(CC)c1ccccc1Nc1nc(Nc2cc3c(cc2OC)CCN(C)C3)ncc1Cl,HPK1,active,5,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3P(C)(C)=O)n1)CCN(C)C2,HPK1,active,5,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3P(C)(C)=O)n1)[C@H](N(C)C)CC2,HPK1,active,5,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCc2cc(OC)c(Nc3ncc(Cl)c(Nc4ccccc4P(C)(C)=O)n3)cc2C1,HPK1,active,5,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3P(C)(C)=O)n1)CN(C(C)C)CC2,HPK1,active,5,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3P(C)(C)=O)n1)CN1CCCCC1C2,HPK1,active,5,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
C=Cc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3P(C)(C)=O)n1)CN(C)CC2,HPK1,active,5,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
CCc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3P(C)(C)=O)n1)CN(C)CC2,HPK1,active,5,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCc2cc(Cl)c(Nc3ncc(Cl)c(Nc4ccccc4P(C)(C)=O)n3)cc2C1,HPK1,active,5,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCc2cc(F)c(Nc3ncc(Cl)c(Nc4ccccc4P(C)(C)=O)n3)cc2C1,HPK1,active,5,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3P(C)(C)=O)n1)CCCN(C)C2,HPK1,active,5,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3P(C)(C)=O)n1)CN(C)CC2,HPK1,active,5,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N)c5ccsc5[nH]c4=O)[nH]c3n2)CC1,HPK1,active,7,ic50,CN109721620A_Original_document_20201120095431, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ccc3nc(-c4c(N)c5ccsc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,5,ic50,CN109721620A_Original_document_20201120095431, not Ki or Kd; not used in NCI fingerprint analysis
Nc1c(-c2nc3ccc(C4CCCNCC4)nc3[nH]2)c(=O)[nH]c2sccc12,HPK1,active,6,ic50,CN109721620A_Original_document_20201120095431, not Ki or Kd; not used in NCI fingerprint analysis
Nc1c(-c2nc3ccc(C4CCNCC4)nc3[nH]2)c(=O)[nH]c2sccc12,HPK1,active,7,ic50,CN109721620A_Original_document_20201120095431, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1COC(=O)N1c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)nnc2c(N)c1Cl,HPK1,active,6.5,ic50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1COC(=O)N1c1cc(N)c2nnc(NC(=O)[C@@H]3C[C@H]3c3cnn(C)c3)cc2c1,HPK1,active,1.2,ic50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1COC(=O)N1c1cc(N)c2nnc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)cc2c1,HPK1,active,1.2,ic50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
COCCn1cc([C@H]2C[C@@H]2C(=O)Nc2cc3cc(N4C(=O)OC[C@@H]4C)cc(N)c3nn2)cn1,HPK1,active,1.2,ic50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1cc([C@H]2C[C@@H]2C(=O)Nc2cc3cc(-c4cncn4C)cc(N)c3nn2)cn1,HPK1,active,2.2,ic50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccnc(F)c1-c1cc(N)c2nnc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)cc2c1,HPK1,active,1,ic50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(N)c3nnc(NC(=O)[C@H]4C[C@@H]4c4cnn(C)c4)cc3c2)cnc2c1NC(=O)CO2,HPK1,active,3.2,ic50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc3cc(NC(=O)[C@H]4C[C@@H]4c4cnn(C)c4)nnc3c(N)c2F)cnn1C,HPK1,active,4.9,ic50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc3cc(NC(=O)[C@@H]4C[C@H]4c4cnn(C)c4)nnc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.84,ic50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc3cc(NC(=O)[C@H]4C[C@@H]4c4cnn(C)c4)nnc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.75,ic50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(N)cncc1-c1cc(N)c2nnc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)cc2c1,HPK1,active,0.97,ic50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2nnc(Nc3ccc4c(n3)CCN(C(C)C)C4=O)cc2c1,HPK1,active,2.9,ic50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(N)c3nnc(Nc4cc5n(n4)CC(=O)N(C(C)C)CC5)cc3c2)cnc2c1NCCO2,HPK1,active,0.84,ic50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(N)c3nnc(NC(=O)[C@@H]4C[C@H]4c4cnn(C)c4)cc3c2)cnc2c1NCCO2,HPK1,active,0.74,ic50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2nnc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)cc2c1,HPK1,active,0.59,ic50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2nnc(NC(=O)[C@@H]3C[C@H]3C#N)cc2c1,HPK1,active,6,ic50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
CNC1CCN(c2cccc(-n3ncc4cnc(-c5c(F)cccc5OC)cc43)n2)CC1,HPK1,active,17,ic50,Merck-Identification of Potent Reverse Indazole Inhibitors for HPK1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1cc2c(cn1)cnn2-c1cccc(N2CCCCC2)n1,HPK1,active,40,ic50,Merck-Identification of Potent Reverse Indazole Inhibitors for HPK1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1cc2c(cn1)cnn2-c1cccc(N2CC3(CCCNC3)C2)n1,HPK1,active,13,ic50,Merck-Identification of Potent Reverse Indazole Inhibitors for HPK1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1cc2c(cn1)cnn2-c1cccc(N2CC(N)C2)n1,HPK1,active,32,ic50,Merck-Identification of Potent Reverse Indazole Inhibitors for HPK1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1cc2c(cn1)cnn2-c1cccc(N2CCOCC2)n1,HPK1,active,34,ic50,Merck-Identification of Potent Reverse Indazole Inhibitors for HPK1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1cc2c(cn1)cnn2-c1ccnc(N2CCN(C)CC2)c1,HPK1,active,60,ic50,Merck-Identification of Potent Reverse Indazole Inhibitors for HPK1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1cc2c(cn1)cnn2-c1ccc(N2CCN(C)CC2)cc1,HPK1,active,89,ic50,Merck-Identification of Potent Reverse Indazole Inhibitors for HPK1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2cc(-c3n[nH]c4cnc(-c5cnn6c5CCC6)cc34)ccn2)CC1,HPK1,active,15,ic50,Merck-Identification of Potent Reverse Indazole Inhibitors for HPK1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1nccc(Nc3ccccc3)n1)CN(C)CC2,HPK1,active,64,ic50,Merck-Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotheray Tool Nc3ccccc3ompounds, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C(N)=O)c(Nc3ccccc3C(C)(C)O)n1)CN(C)CC2,HPK1,active,11.4,ic50,Merck-Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotheray Tool Compounds, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C(N)=O)c(Nc3c(C)cccc3C)n1)CN(C)CC2,HPK1,active,14,ic50,Merck-Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotheray Tool Compounds, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(NC5CCCOC5)c5ccsc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CN(c2ccc3nc(-c4c(N)c5ccsc5[nH]c4=O)[nH]c3c2)C[C@@H](C)O1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N[C@@H]5CCC[C@H]5O)c5cscc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
COCCNc1c(-c2nc3ccc(N4CCN(C)CC4)cc3[nH]2)c(=O)[nH]c2sccc12,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
O=c1[nH]c2sccc2c(N[C@H]2CCCC[C@H]2O)c1-c1nc2ccc(N3CCOCC3)cc2[nH]1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N[C@@H]5CCOC5)c5cscc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2cc3[nH]c(-c4c(N)c5sccc5[nH]c4=O)nc3cc2F)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N[C@@H]5CCC[C@H]5O)c5ccsc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N[C@H]5CCC[C@@H]5O)c5ccsc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
Nc1c(-c2nc3ccc(N4CCN(C5COC5)CC4)cc3[nH]2)c(=O)[nH]c2sccc12,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)OC(=O)N1CCN(c2ccc([N+](=O)O)c(N)c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2[nH]c(-c3c(N)c4ccsc4[nH]c3=O)nc2cc1N1CCN(C)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N[C@H]5CCC[C@H]5O)c5ccsc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(NC5CCCC[C@H]5O)c5ccsc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
Nc1c(-c2nc3cc(F)c(N4CCOCC4)cc3[nH]2)c(=O)[nH]c2sccc12,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N[C@H]5CCNC[C@H]5F)c5ccsc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N[C@H]5CCNC[C@@H]5F)c5ccsc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(NCc5ccccn5)c5sccc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(NCc5cccnc5)c5sccc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CN(c2ccc3nc(-c4c(NC5CCOCC5)c5sccc5[nH]c4=O)[nH]c3c2)C[C@@H](C)N1C,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CN(c2ccc3nc(-c4c(NC5CCCC5)c5sccc5[nH]c4=O)[nH]c3c2)C[C@@H](C)N1C,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N[C@@H]5CCCC[C@@H]5O)c5sccc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(Nc2c(-c3nc4ccc(N5CCOCC5)cc4[nH]3)c(=O)[nH]c3ccsc23)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N[C@H]5CCCC[C@H]5O)c5sccc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
O=c1[nH]c2ccsc2c(NC2CCNCC2)c1-c1nc2ccc(N3CCOCC3)cc2[nH]1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N[C@H]5CCC[C@@H]5O)c5sccc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N[C@H]5CCCC[C@@H]5O)c5sccc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N[C@H]5CC[C@@H](O)CC5)c5sccc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(NC5CCNCC5)c5sccc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(NCC5CCOCC5)c5sccc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N[C@H]5CC[C@H](O)CC5)c5sccc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N[C@@H]5CC[C@H](O)C5)c5sccc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(NC5CCOCC5)c5sccc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(NC5CCCC5)c5sccc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CN(c2ccc3nc(-c4c(N)c5sccc5[nH]c4=O)[nH]c3c2)C[C@@H](C)N1C,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
Nc1c(-c2nc3ccc(N4CCOCC4)cc3[nH]2)c(=O)[nH]c2ccsc12,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N)c5sccc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(O)c5sccc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(NCc5ccccn5)c5cscc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(NC5CCC5)c5cscc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(NCCN5CCOCC5)c5cscc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(NC5CCOCC5)c5cscc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(NC5CCCC5)c5cscc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N)c5cscc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(NCc5ccncc5)c5sccc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N)c5c(N6CCNCC6)csc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(Nc2c(-c3nc4ccc(N5CCOCC5)cc4[nH]3)c(=O)[nH]c3sccc23)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(NC5CCN(C=O)CC5)c5ccsc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)[C@H](CO)Nc1c(-c2nc3ccc(N4CCN(C)CC4)cc3[nH]2)c(=O)[nH]c2sccc12,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(NC5CCNCC5(F)F)c5ccsc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N[C@@H]5CCNC[C@H]5F)c5ccsc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N[C@@H]5CC[C@H](O)C5)c5ccsc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N[C@H]5C[C@@H](O)C5)c5ccsc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N[C@H]5CCOC5)c5ccsc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N[C@@H]5CCOC5)c5ccsc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N[C@@H]5CC[C@@H](O)C5)c5ccsc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N[C@H]5C[C@H](O)C5)c5ccsc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(NC5CCOCC5)c5ccsc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
Nc1c(-c2nc3ccc(N4CCOCC4)cc3[nH]2)c(=O)[nH]c2sccc12,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
Cc1csc2[nH]c(=O)c(-c3nc4ccc(N5CCN(C)CC5)cc4[nH]3)c(N)c12,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N)c5ccsc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cnc2cc(-c3cnc4c(c3)N([C@H]3C[C@@H](N5CCCCC5)C3)C(=O)C4(C)C)nc(Nc3ccncc3F)c21,HPK1,active,13.2,ic50,WO2020092528A1_Original_document_20201118034406, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(/C=C3/C(=O)Nc4ccc(-c5ccccc5F)cc43)cc2)CC1,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc2c(cn1)NC(=O)/C2=C\c1[nH]c(C)c(C(=O)NCC(C)(C)O)c1C,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccncc1-c1cc2c(cn1)NC(=O)/C2=C\c1[nH]c(C)c(-c2cnn(C)c2)c1C,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc2c(cn1)NC(=O)/C2=C\c1[nH]c(C)c(/C(C=N)=C/NC2COC2)c1C,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc2c(cn1)NC(=O)/C2=C\c1[nH]c(C)c(C(=O)N2CCOCC2)c1C,HPK1,medium,100,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
CCn1cc(-c2c(C)[nH]c(/C=C3\C(=O)Nc4cnc(-c5cnccc5C)cc43)c2C)cn1,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc2c(cn1)NC(=O)C2=Cc1[nH]c(C)c(C(=O)N2CC[C@@H](F)C2)c1C,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc2c(cn1)NC(=O)/C2=C\c1[nH]c(C)c(C(=O)N2CCC(F)CC2)c1C,HPK1,active,50.01,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc2c(cn1)NC(=O)/C2=C\c1[nH]c(C)c(-c2ccn(C)n2)c1C,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc2c(cn1)NC(=O)/C2=C\c1[nH]c(C)c(C(=O)N2CC[C@H](F)C2)c1C,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc2c(cn1)NC(=O)/C2=C\c1[nH]c(C)c(C(=O)N2CCC(O)CC2)c1C,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc2c(cn1)NC(=O)/C2=C\c1[nH]c(C)c(C(=O)NCCN2CCOCC2)c1C,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1nc(C)c(/C=C2\C(=O)Nc3cnc(-c4cnccc4C)cc32)[nH]1,HPK1,active,50.01,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(C)c(C=C2C(=O)Nc3cnc(-c4cnccc4C)cc32)[nH]1,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1cc2c(cn1)NC(=O)/C2=C\c1[nH]c(C)c(C(=O)NCC(C)(C)O)c1C,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc2c(cn1)NC(=O)/C2=C\c1[nH]c(C)c(C(=O)N2CC[C@@H](O)C2)c1C,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc2c(cn1)NC(=O)/C2=C\c1[nH]c(C)c(C(=O)NC(C)(C)CO)c1C,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc2c(cn1)NC(=O)/C2=C\c1[nH]c(C)c(-c2cnn(C)c2)c1C,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3cnc(-c4cnccc4C)cc32)c1C,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3cnc(-c4c(F)cccc4OC)cc32)c1C,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1cc2c(cn1)NC(=O)/C2=C\c1[nH]c(C)c(-c2cnn(C)c2)c1C,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN(CC)CCNC(=O)c1c(C)[nH]c(C=C2C(=O)Nc3ccc(-c4c(O)cccc4F)cc32)c1C,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1ccc2c(c1)/C(=C/c1[nH]c(C)c(-c3cnn(C)c3)c1C)C(=O)N2,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1Nc2ccc(-c3c(F)cccc3F)cc2C1=Cc1ccc(N2CCN(C3COC3)CC2)nc1,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1ccc2c(c1)C(=Cc1ccc(N3CCN(C4COC4)CC3)cn1)C(=O)N2,HPK1,active,50.01,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1ccc2c(c1)C(=Cc1ccc(N3CCN(C(C)=O)CC3)nc1)C(=O)N2,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1ccc2c(c1)C(=Cc1ccc(N3CCN(CC(F)(F)F)CC3)nc1)C(=O)N2,HPK1,active,50.01,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1ccc2c(c1)C(=Cc1[nH]c(C)c(-c3cn(C4CCN(C)CC4)nn3)c1C)C(=O)N2,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1ccc2c(c1)C(=Cc1cnc(N3CCN(C4COC4)CC3)nc1)C(=O)N2,HPK1,active,50.01,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1ccc2c(c1)C(=Cc1ccc(N3CCOCC3)nc1)C(=O)N2,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1ccc2c(c1)/C(=C/c1ccc(N3CCN(C4COC4)CC3)nc1)C(=O)N2,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1ccc2c(c1)/C(=C/c1ccc(N3CCN(C)CC3)nc1)C(=O)N2,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1ccc2c(c1)C(=Cc1ccc(N3CCC(O)CC3)cc1)C(=O)N2,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1ccc2c(c1)C(=Cc1ccc(N3CCN(C4COC4)CC3)nc1)C(=O)N2,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1ccc2c(c1)C(=Cc1cnn(C3CCN(C)CC3)c1)C(=O)N2,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1ccc2c(c1)C(=Cc1ccc(N3CCN(C)CC3)nc1)C(=O)N2,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN(CC)CCOc1ccc(/C=C2/C(=O)Nc3ccc(-c4c(F)cccc4OC)cc32)cc1,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1ccc2c(c1)C(=Cc1ccc(N3CCOCC3)cc1)C(=O)N2,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1ccc2c(c1)C(=Cc1ccc(N3CCN(C)CC3)cc1)C(=O)N2,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(/C=C3\C(=O)Nc4ccc(-c5ccccc5F)cc43)cc2)CC1,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c(C=C2C(=O)Nc3ccc(F)cc32)c(C)c1-c1cn(C2CCN(C)CC2)nn1,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c(C=C2C(=O)Nc3ccc(F)cc32)c(C)c1-c1ccc(C(=O)N2CCN(C)CC2)cc1,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c(C=C2C(=O)Nc3ccc(F)cc32)c(C)c1-c1ccc(C(=O)N2CCOCC2)cc1,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c(/C=C2/C(=O)Nc3ccc(F)cc32)c(C)c1-c1ccc(CN2CCN(C)CC2)cc1,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c(/C=C2/C(=O)Nc3ccc(F)cc32)c(C)c1-c1cn(C2CCNCC2)nn1,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c(/C=C2/C(=O)Nc3ccc(F)cc32)c(C)c1-c1cnn(C2CCNCC2)c1,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN(CC)CCOc1ccc(-c2c(C)[nH]c(/C=C3/C(=O)Nc4ccc(F)cc43)c2C)cc1,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c(/C=C2/C(=O)Nc3ccc(F)cc32)c(C)c1-c1ccc(N2CCN(C)CC2)cc1,HPK1,active,50,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c(-c2cc3cc(NC(=O)O[C@@H]4COC[C@H]4C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
CO[C@H]1COC[C@@H]1OC(=O)Nc1cc2cc(-c3cnc4c(c3C)NCCO4)c(F)c(N)c2cn1,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
CNc1cncc(-c2cc3cc(NC(=O)OC4CC(C)(O)C4)ncc3c(N)c2F)c1C,HPK1,active,64,ic50,WO2020072695A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CCO[C@H]4C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4COC[C@@H]4F)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.02,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@H](C#N)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.015,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4COC[C@@H]4C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N4CC(C)(F)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.09,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N4CC(C)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.044,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@H](C(C)(C)O)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.02,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CCC[C@H]4C#N)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CCOC4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CCOCC4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.019,Ki,WO2020072695A1,Below 1 nM
CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc4c3OCCN4)cc2)n(-c2cccc(C#N)c2)n1,HPK1,active,50,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc4c3OCCCN4)cc2F)n(-c2ccc(C#N)cc2)n1,HPK1,active,50,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc4c3OCCCN4)cc2F)n(-c2cccc(C#N)c2)n1,HPK1,active,50,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc4c3OCCCN4)cc2F)n(-c2cccc(C(N)=O)c2)n1,HPK1,active,50,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)COc2c(ncnc2Oc2ccc(NC(=O)Nc3cc(C(C)(C)C)nn3-c3cccc(C#N)c3)cc2Cl)N1,HPK1,active,50,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4ncnc5c4OCC(C)(C)N5)c(C)c3)cc2C(F)(F)F)CC1,HPK1,active,50,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4ncnc5c4OCC(C)(C)N5)c(Cl)c3)cc2C(F)(F)F)CC1,HPK1,active,50,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)COc2c(ncnc2Oc2ccc(NC(=O)Nc3cc(C(C)(C)C)nn3-c3ccc(C#N)cc3)cc2Cl)N1,HPK1,active,50,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4ncnc5c4OCC(C)(C)N5)c(F)c3)cc2C(F)(F)F)CC1,HPK1,active,50,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4ncnc5c4OCC(C)(C)N5)cc3)cc2C(F)(F)F)CC1,HPK1,active,50,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4ccnc5c4OCCCN5)cc3F)cc2C(F)(F)F)CC1,HPK1,active,50,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4ncnc5c4OC[C@@H](C)N5)c(F)c3)cc2C(F)(F)F)CC1,HPK1,active,50,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OC[C@@H](COC)N5)c3)cc2C(F)(F)F)CC1,HPK1,active,50,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4ncnc5c4OC[C@@H](C)N5)cc3)cc2C(F)(F)F)CC1,HPK1,active,50,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4ccnc5c4OCCCN5)cc3)cc2C(F)(F)F)CC1,HPK1,active,50,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4ncnc5c4OCCN5)cc3Cl)cc2C(F)(F)F)CC1,HPK1,active,50,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4ncnc5c4OCCN5)cc3F)cc2C(F)(F)F)CC1,HPK1,active,50,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4ccnc5c4OCCN5)cc3)cc2C(F)(F)F)CC1,HPK1,active,50,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4ncnc5c4OC[C@@H](C)N5)c(Cl)c3)cc2C(F)(F)F)CC1,HPK1,active,50,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1COc2c(ncnc2Oc2cc(C(=O)Nc3ccc(CN4CCN(CC)CC4)c(C(F)(F)F)c3)ccc2Cl)N1,HPK1,active,50,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4ncnc5c4OCCN5)c(Cl)c3)cc2C(F)(F)F)CC1,HPK1,active,50,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCC(C)(C)N5)c3)cc2C(F)(F)F)CC1,HPK1,active,50,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OC[C@H](C)N5)c3)cc2C(F)(F)F)CC1,HPK1,active,50,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OC[C@@H](C)N5)c3)cc2C(F)(F)F)CC1,HPK1,active,50,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1Nc2ccc(-c3cnc4c(c3)NCCO4)cc2C1=Cc1cnc[nH]1,HPK1,active,66.7,ic50,WO_2020237025_A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)c1cnc(NC2=CC3C(C=C2)C(=O)OC3(C)C)nc1N[C@H](CO)c1ccccc1,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
C#[N+]C1(c2nnc(-c3cnc(Nc4ccc5c(n4)C(C)(C)OC5=O)cc3N[C@H](CO)c3ccccc3)o2)CC1,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
O=C1OC2(CCCC2)c2nc(Nc3cc(N[C@H](CO)c4ccccc4)c(-c4nc(C5CC5)no4)cn3)ccc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3cc(N[C@H](CO)c4ccccc4)c(-c4nnc(C5CC5)o4)cn3)nc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3cc(NCc4cccnc4)c(-c4nc(C56CCN(CC5)CC6)no4)cn3)nc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3cc(NCc4nccs4)c(-c4nc(C56CCN(CC5)CC6)no4)cn3)nc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3cc(N[C@H](CO)c4ccccc4)c(-c4nc(C5CN6CCC5(F)CC6)no4)cn3)nc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3cc(N[C@H](CO)c4ccc(F)cc4)c(-c4nc(C56CCN(CC5)CC6)no4)cn3)nc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3cc(N[C@H](CO)c4ccccc4)c(-c4nc(C56CCN(CC5)CC6)no4)cn3)nc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(CN)CNc1nc(Nc2ccc3c(c2)C(C)(C)OC3=O)ncc1-c1nc(C2CCOCC2)no1,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)c1cnc(Nc2ccc3c(c2)C(C)(C)OC3=O)nc1NCc1ccccc1C(C)(C)O,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(-c4nnc(C5CCS(=O)(=O)CC5)o4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(-c4nnc(C5(C(F)(F)F)CC5)o4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(-c4nnc(-c5cccnn5)o4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(-c4nnc(C(C)(O)C(F)(F)F)o4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(C(=O)NNC(=O)C4CC4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)c1nnc(-c2cnc(Nc3ccc4c(c3)C(C)(C)OC4=O)nc2N[C@H](CO)c2ccccc2)o1,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC/N=C(\NCCCN(C)C)NNC(=O)c1cnc(Nc2ccc3c(c2)C(C)(C)OC3=O)nc1N[C@H](CO)c1ccccc1,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(C(=O)NNC(=O)c4cnccn4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(-c4nnc(-c5cccnc5)o4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(C(=O)NNC(=O)c4cccnc4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CCn1nc(-c2cnc(Nc3ccc4c(c3)C(C)(C)OC4=O)nc2N[C@H](CO)c2ccccc2)oc1=O,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(-c4n[nH]c(=O)o4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(C(=O)NN)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)NC12CC(c3noc(-c4cnc(Nc5ccc6c(c5)C(C)(C)OC6=O)nc4N[C@H](CO)c4ccccc4)n3)(C1)C2,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)NC12CC(c3noc(-c4cnc(Nc5ccc6c(c5)C(C)(C)OC6=O)nc4N[C@H](CO)c4ccccc4)n3)(C1)C2,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)C12CC(c3noc(-c4cnc(Nc5ccc6c(c5)C(C)(C)OC6=O)nc4N[C@H](CO)c4ccccc4)n3)(C1)C2,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(-c4nc(C56CC(N)(C5)C6)no4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3cc(N[C@H](CO)c4ccccc4)c(-c4nc(C56CCN(CC5)CC6)no4)cn3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(-c4nc(-c5ccc(F)cc5)no4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(-c4nc(-c5cccnc5)no4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(-c4nc(-c5ccccn5)no4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(CO)c1noc(-c2cnc(Nc3ccc4c(c3)C(C)(C)OC4=O)nc2N[C@H](CO)c2ccccc2)n1,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(-c4nc(C5CC(F)(F)C5)no4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(-c4nc(C5(CO)CC5)no4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(CCCO)c1noc(-c2cnc(Nc3ccc4c(c3)C(C)(C)OC4=O)nc2N[C@H](CO)c2ccccc2)n1,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CCCCc1noc(-c2cnc(Nc3ccc4c(c3)C(C)(C)OC4=O)nc2N[C@H](CO)c2ccccc2)n1,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CCCc1noc(-c2cnc(Nc3ccc4c(c3)C(C)(C)OC4=O)nc2N[C@H](CO)c2ccccc2)n1,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(-c4nc(C5CCOCC5)no4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(-c4nc(CN5CCOCC5)no4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(-c4nc(N5CCOCC5)no4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(C4=NCC5(CCOCC5)O4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(C(=O)NCC4(CN5CCOCC5)CC4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(C(=O)NCC4CN5CCC4CC5)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(C(=O)NC[C@@]4(O)CN5CCC4CC5)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(CNC(=O)c2cnc(Nc3ccc4c(c3)C(C)(C)OC4=O)nc2N[C@H](CO)c2ccccc2)COC1,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(C(=O)NC4CCN(Cc5ccccc5)C4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
C#CCNC(=O)c1cnc(Nc2ccc3c(c2)C(C)(C)OC3=O)nc1N[C@H](CO)c1ccccc1,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cnc(CNC(=O)c2cnc(Nc3ccc4c(c3)C(C)(C)OC4=O)nc2N[C@H](CO)c2ccccc2)cn1,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(C(=O)NCCCn4ccnc4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1cnc(Nc2ccc3c(c2)C(C)(C)OC3=O)nc1N[C@H](CO)c1ccccc1,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)NC(=O)c1cnc(Nc2ccc3c(c2)C(C)(C)OC3=O)nc1N[C@H](CO)c1ccccc1,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)CNC(=O)c1cnc(Nc2ccc3c(c2)C(C)(C)OC3=O)nc1N[C@H](CO)c1ccccc1,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)NC(=O)c1cnc(Nc2ccc3c(c2)C(C)(C)OC3=O)nc1N[C@H](CO)c1ccccc1,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(C(=O)NCc4ccccc4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCNC(=O)c1cnc(Nc2ccc3c(c2)C(C)(C)OC3=O)nc1N[C@H](CO)c1ccccc1,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
COCCNC(=O)c1cnc(Nc2ccc3c(c2)C(C)(C)OC3=O)nc1N[C@H](CO)c1ccccc1,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(C(=O)NCCCN4CCOCC4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(C(=O)NCc4ccccn4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCCNC(=O)c1cnc(Nc2ccc3c(c2)C(C)(C)OC3=O)nc1N[C@H](CO)c1ccccc1,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(C(=O)NCC4CC(F)(F)C4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
O=C1OCc2cc(Nc3ncc(-c4ncccn4)c(N[C@H](CO)c4ccccc4)n3)ccc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(O)N(C)Cc5ccn(C)n5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,79,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(O)N(C)CCN5CCN(C)CC5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,46,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(O)N(C)C5CC5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,44,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC[C@](C)(O)C5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,55,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C5CCC(C)(C)CC5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,53,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CC2CN(c3ccc(-c4cnc5[nH]cc(-c6ccc(C(=O)N(C)C)cc6)c5c4)cc3)CC2C1,HPK1,active,59,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ccc(-c3cnc4[nH]cc(-c5ccc(OCCN)cc5)c4c3)cc2F)CC1,HPK1,active,45,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@H](C)O)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,10,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CCn1cc(-c2cnc3[nH]cc(-c4ccc(OC)cc4)c3c2)cn1,HPK1,active,19,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@@H](C)O)cc4)c3c2)ccc1[C@@H]1CCCN(C)C1,HPK1,active,49,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@@H](C)O)cc4)c3c2)ccc1[C@H]1CCCN(C)C1,HPK1,active,37,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4ccc([C@@H]5CCCN(C)C5)c(C)c4)cc23)ccc1C(=O)N(C)C,HPK1,active,77,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4ccc([C@H]5CCCN(C)C5)c(C)c4)cc23)ccc1C(=O)N(C)C,HPK1,active,82,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)ccc1[C@H]1CCCN(C)C1,HPK1,active,14,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)ccc1[C@@H]1CCCN(C)C1,HPK1,active,11,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC[C@@](C)(O)C5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,99,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc([C@@H](O)C5CN(C)C5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,16,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc([C@H](O)C5CN(C)C5)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,10,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@H](C)O)cc4)c3c2)ccc1[C@@H]1CCCN(C)C1,HPK1,active,15,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@H](C)O)cc4)c3c2)ccc1[C@H]1CCCN(C)C1,HPK1,active,19,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC[C@@H](O)C5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,56,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c(N5CCN(C)CC5)c(C)c4)nc23)ccc1C(=O)N(C)C,HPK1,active,21,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c(N5CCN(C)CC5)c(C)c4)cc23)ccc1C(=O)NC[C@@H](C)O,HPK1,active,53,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)c(C5CC5)c4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,56,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CCOc1cc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)c(C)c4)cc23)ccc1C(=O)N(C)C,HPK1,active,86,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)c(C)c4)cc23)ccc1C(=O)N(C)C,HPK1,active,75,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)CC(C)(C)O)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,51,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC[C@H](O)C5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,86,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(N(C)C(=O)c2ccc(-c3c[nH]c4ncc(-c5ccc(N6CCN(C)CC6)c(C)c5)cc34)cc2)cn1,HPK1,active,57,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C5CCOC5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,92,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)c5c(C)cccc5Cl)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,48,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)c5ccn(C)n5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,66,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)c5ccc(F)cc5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,68,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C5=CCCC=C5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,63,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)CC5CCOC5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,19,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)[C@H]5CC[C@](C)(O)CC5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,51,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C5CCN(C)CC5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,54,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C(C)C)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,65,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc(C)c1C1CCN(C)CC1,HPK1,active,16,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@H](C)O)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,14,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CNC1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc6c(c5)CCN(C)C6=O)c4c3)cc2C)CC1,HPK1,active,27,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc5c(c4)CCN(C)C5=O)c3c2)ccc1N1CCN(C)CC1,HPK1,active,19,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC6(CCOC6)C5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,85,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)ccc1C1CCCN(C)C1,HPK1,active,22,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN[C@H]1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2C)C1,HPK1,active,32,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN[C@@H]1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2C)C1,HPK1,active,33,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN[C@H]1CCCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2C)C1,HPK1,active,37,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN[C@@H]1CCCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2C)C1,HPK1,active,26,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(C)(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2)CC1,HPK1,active,83,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2C(F)(F)F)CC1,HPK1,active,41,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCCC2(C1)CN(c1ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc1)C2,HPK1,active,98,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2NCc2ccccc2)CC1,HPK1,active,43,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2NC2CC2)CC1,HPK1,active,17,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CCNc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,58,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CNC1CN(C(=O)c2ccc(-c3c[nH]c4ncc(-c5ccc(N6CCN(C)CC6)c(C(F)(F)F)c5)cc34)cc2)C1,HPK1,active,38,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)c(C(F)(F)F)c4)cc23)cc1,HPK1,active,33,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC(N(C)C)C6)cc5)c4c3)cc2OC(F)(F)F)CC1,HPK1,active,15,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC7(COC7)C6)cc5)c4c3)cc2OC(F)(F)F)CC1,HPK1,active,52,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC7(COC7)C6)cc5)c4c3)cc2F)CC1,HPK1,active,43,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(O)C6CN(C)C6)cc5)c4c3)cc2F)CC1,HPK1,active,16,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC(O)C5)cc4)c3c2)ccc1C1CCN(C)CC1,HPK1,active,18,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(O)C5CN(CCN(C)C)C5)cc4)c3c2)ccc1C1CCN(C)CC1,HPK1,active,64,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(O)C5CN(C)C5)cc4)c3c2)ccc1C1CCN(C)CC1,HPK1,active,11,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)ccc1N1CC2CN(C)CC2C1,HPK1,active,19,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(C5CCCCN5)cc4)cc23)cc1,HPK1,active,59,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)C5CNC5)cc4)c3c2)ccc1C1CCN(C)CC1,HPK1,active,12,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)C5CNC5)cc4)c3c2)ccc1C1CCN(C)CC1,HPK1,active,11,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc5c(c4)OCCN(C)C5=O)c3c2)ccc1C1CCN(C)CC1,HPK1,active,17,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc5c(c4)OCCN(C)C5=O)c3c2)ccc1C1CCN(C)CC1,HPK1,active,21,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc5c(c4)CCN(C)C5=O)c3c2)ccc1C1CCN(C)CC1,HPK1,active,16,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc5c(c4)CCN(C)C5=O)c3c2)ccc1C1CCN(C)CC1,HPK1,active,21,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2F)CC1,HPK1,active,41,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CNC1CN(C(=O)c2ccc(-c3c[nH]c4ncc(-c5ccc(C6CCN(C)CC6)c(C)c5)cc34)cc2)C1,HPK1,active,13,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)CCN(C)C)cc4)c3c2)ccc1C1CCN(C)CC1,HPK1,active,19,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)ccc1C1CCN(C)CC1,HPK1,active,21,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(C5CCN(C)CC5)cc4)cc23)cc1,HPK1,active,23,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC(N(C)C)C6)cc5)c4c3)cc2)CC1,HPK1,active,19,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC(O)C6)cc5)c4c3)cc2)CC1,HPK1,active,23,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ccc(-c3cnc4[nH]cc(-c5ccc6c(c5)CCN(C)C6=O)c4c3)cc2)CC1,HPK1,active,17,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc6c(c5)CCCN(C)C6=O)c4c3)cc2)CC1,HPK1,active,34,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc6c(c5)CCN(C)C6=O)c4c3)cc2F)CC1,HPK1,active,32,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc5c(c4)CCN(C)C5=O)c3c2)ccc1N1CCN(C)CC1,HPK1,active,25,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc6c(c5)CCN(C)C6=O)c4c3)cc2C#N)CC1,HPK1,active,34,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC(N(C)C)C6)cc5)c4c3)cc2F)CC1,HPK1,active,30,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCCC(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2)C1,HPK1,active,41,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2C2CCOC2)CC1,HPK1,active,92,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2C2CNC(=O)C2)CC1,HPK1,active,76,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2-c2cn[nH]c2)CC1,HPK1,active,36,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4ccc(C5CCN(C)CC5)c(C#N)c4)cc23)ccc1C(=O)N(C)C,HPK1,active,22,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC(O)C5)cc4)c3c2)cc(F)c1N1CCN(C)CC1,HPK1,active,26,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC6(COC6)C5)cc4)c3c2)cc(F)c1N1CCN(C)CC1,HPK1,active,50,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc(F)c1N1CCN(C)CC1,HPK1,active,35,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC7(COC7)C6)cc5)c4c3)cc2C(F)(F)F)CC1,HPK1,active,39,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC(O)C6)cc5)c4c3)cc2C(F)(F)F)CC1,HPK1,active,49,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC(O)C6)cc5)c4c3)cc2F)CC1,HPK1,active,30,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC7(COC7)C6)cc5)c4c3)cc2F)CC1,HPK1,active,54,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc5c(c4)OCCN(C)C5=O)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,13,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc5c(c4)CN(C)C5=O)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,56,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)ccc1C1CCN(C)CC1,HPK1,active,19,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC(O)C6)cc5)c4c3)cc2C#N)CC1,HPK1,active,30,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2OC(F)(F)F)CC1,HPK1,active,68,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
N#Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC(O)C5)cc4)c3c2)ccc1N1CCN(CCO)CC1,HPK1,active,53,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC(O)C5)cc4)c3c2)ccc1N1CCN(CCO)CC1,HPK1,active,29,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC(O)C5)cc4)c3c2)cc(C#N)c1N1CCN(CCO)CC1,HPK1,active,17,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC(O)C5)cc4)c3c2)cc(C)c1N1CCN(C2CCN(CCO)CC2)CC1,HPK1,active,14,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC6(CC(O)C6)C5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,87,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC6(CC(O)C6)C5)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,30,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC6(CC(O)C6)C5)cc4)c3c2)cc(C)c1N1CCN(C2CCN(C)CC2)CC1,HPK1,active,17,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c(N5CCN(C6CCN(C)CC6)CC5)c(C)c4)cc23)ccc1C(=O)N1CC2(CC(O)C2)C1,HPK1,active,36,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC(O)C5)cc4)c3c2)cc(C#N)c1N1CCN(C2CCN(C)CC2)CC1,HPK1,active,12,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c(N5CCN(C6CCN(C)CC6)CC5)c(C)c4)cc23)ccc1C(=O)N1CC(O)C1,HPK1,active,25,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)CCN(C)C)cc4)c3c2C)cc(C)c1N1CCN(C2CCN(C)CC2)CC1,HPK1,active,20,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)CCN(C)C)cc4)c3c2)cc(OC)c1N1CCN(C2CCN(C)CC2)CC1,HPK1,active,13,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC6(COC6)C5)cc4)c3c2)cc(OC)c1N1CCN(C2CCN(C)CC2)CC1,HPK1,active,28,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(O)C5CC5)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,25,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CNC1(c2ccc(-c3c[nH]c4ncc(-c5cc(C)c(N6CCN(C)CC6)c(C)c5)cc34)cc2)CC1,HPK1,active,80,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc(C)c1N1CCN(CCO)CC1,HPK1,active,12,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC6(COC6)C5)cc4)c3c2)cc(C)c1N1CCN(CCO)CC1,HPK1,active,11,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(OCCC(=O)N(C)C)cc4)c3c2)cc(C)c1N1CCN(C2CCN(C)CC2)CC1,HPK1,active,10,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC6(CN(C)C6)C5)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,15,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2C#N)CC1,HPK1,active,37,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COC1CC(N(C)C(=O)c2ccc(-c3c[nH]c4ncc(-c5cc(C)c(N6CCN(C)CC6)c(C)c5)cc34)cc2)C1,HPK1,active,44,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC6(COC6)C5)cc4F)c3c2)cc(C)c1N1CCN(C2CCN(C)CC2)CC1,HPK1,active,54,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC(O)C5)cc4F)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,14,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC(O)C5)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,10,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(OCCN)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,25,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(CCC(O)c2ccc(-c3c[nH]c4ncc(-c5cc(C)c(N6CCN(C)CC6)c(C)c5)cc34)cc2)cc1,HPK1,active,58,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2F)CC1,HPK1,active,70,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(N2CCN(c3c(Cl)cc(-c4cnc5[nH]cc(-c6ccc(C(=O)N7CC(O)C7)cc6)c5n4)cc3Cl)CC2)CC1,HPK1,active,33,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4cc(Cl)c(N5CCN(C6CCN(C)CC6)CC5)c(Cl)c4)nc23)cc1,HPK1,active,27,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(N2CCN(c3c(Cl)cc(-c4cnc5[nH]cc(-c6ccc(C(=O)N(C)C)cc6)c5n4)cc3Cl)CC2)CC1,HPK1,active,44,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c(N5CCN(C6CCN(C)CC6)CC5)c(C)c4)nc23)ccc1C(=O)N1CC2(COC2)C1,HPK1,active,11,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c(N5CCN(C6CCN(C)CC6)CC5)c(C)c4)nc23)ccc1C(=O)N(C)CCN(C)C,HPK1,active,11,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC(N(C)C)C5)cc4)c3n2)cc(OC)c1N1CCN(C2CCN(C)CC2)CC1,HPK1,active,13,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC6(COC6)C5)cc4)c3n2)cc(C)c1N1CCN(CCO)CC1,HPK1,active,13,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(OCCC(=O)N(C)C)cc4)c3n2)ccc1N1CCN(C)CC1,HPK1,active,42,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(OCCC(=O)N(C)C)cc4)c3n2)cc(C)c1N1CCN(C)CC1,HPK1,active,14,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC(N(C)C)C5)cc4)c3n2)ccc1N1CCN(C)CC1,HPK1,active,44,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(OCCC(=O)N(C)C)cc4)c3n2)cc(C)c1N1CCN(C2CCN(C)CC2)CC1,HPK1,active,14,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC6(COC6)C5)cc4)c3n2)ccc1N1CCN(C)CC1,HPK1,active,25,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(OCCC(=O)N(C)C)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,19,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COC1CN(C(=O)c2ccc(-c3c[nH]c4ncc(-c5cc(C)c(N6CCN(C)CC6)c(C)c5)cc34)cc2)C1,HPK1,active,42,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(-c5ccn[nH]5)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,72,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC6(COC6)C5)cc4)c3n2)cc(C)c1N1CCN(C2CCN(C)CC2)CC1,HPK1,active,11,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)CCOc1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)c(C#N)c4)cc23)cc1,HPK1,active,59,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4F)c3c2)cc(C)c1N1CCN(C2CCN(C)CC2)CC1,HPK1,active,10,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(OCC(=O)N(C)C)nc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,64,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC(N(C)C)C6)cc5)c4n3)cc2C#N)CC1,HPK1,active,46,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)CCN(C)C)cc4)c3c2)cc(OC)c1N1CCN(C)CC1,HPK1,active,22,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC(N(C)C)C6)cc5)c4c3)cc2C#N)CC1,HPK1,active,26,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC(N(C)C)C5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,18,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(OCCC(=O)N(C)C)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,16,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CCOc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,23,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(OCC(=O)N(C)C)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,32,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)Oc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,62,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN[C@H]1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C[C@H](C)O)cc5)c4c3)cc2C)C1,HPK1,active,25,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(CN(C)C(=O)c2ccc(-c3c[nH]c4ncc(-c5cc(C)c(N6CCN(C)CC6)c(C)c5)cc34)cc2)cc1,HPK1,active,63,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=N)N(C)C)cc4)c3c2)cc(O)c1N1CCN(C)CC1,HPK1,active,14,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CNCCc1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,active,53,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)CCN(C)C)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,29,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC6(COC6)C5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,64,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COCCCN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)c(C)c4)cc23)cn1,HPK1,active,53,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(N5CCCC5=O)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,81,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)CCCN(C)C)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,22,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(OCCN)nc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,35,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)CCN(C)C)cc4)c3c2)cc(C)c1N1CCN(C2CCN(C)CC2)CC1,HPK1,active,10,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC6(COC6)C5)cc4)c3c2)cc(C)c1N1CCN(C2CCN(C)CC2)CC1,HPK1,active,13,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc(C)c1N1CCN(C2CCN(C)CC2)CC1,HPK1,active,11,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2C2CC2)CC1,HPK1,active,35,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc(C)c1CN1CCN(CC2CC2)CC1,HPK1,active,12.5,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc(OCc2ccccc2)c1N1CCN(C)CC1,HPK1,active,96,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC6(COC6)C5)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,27,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC6(COC6)C5)cc4)c3c2)cc(OC)c1N1CCN(C)CC1,HPK1,active,31,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc(OC)c1N1CCN(C)CC1,HPK1,active,35,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,17,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)CC(C)(C)O)cc4)c3n2)cc(C)c1N1CCN(C)CC1,HPK1,active,61,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(S(=O)(=O)CCCN)cc5)c4c3)cc2)CC1,HPK1,active,45,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(OCCC(=O)O)cc5)c4c3)cc2)CC1,HPK1,active,15,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c(N5CCN(C)CC5)c(C)c4)nc23)ccc1C(=O)N1CC2(COC2)C1,HPK1,active,38,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC6(COC6)C5)cc4)c3n2)cc(C)c1N1CCN(C)CC1,HPK1,active,22,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CNC1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C[C@@H](C)O)cc5)c4c3)cc2C)C1,HPK1,active,69,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)CCN5CCN(C)CC5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,46,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)Cc5ccn(C)n5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,79,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C5CCN(C)C5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,65,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C5CC5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,44,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CNC1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2C)CC1,HPK1,active,27,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)ccc1C1CCNCC1,HPK1,active,29,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2O)CC1,HPK1,active,46,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CCCNc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,87,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc5c(c4)OCC(c4ccccc4)N(C)C5=O)c3c2)ccc1N1CCN(C)CC1,HPK1,active,44,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)c(C#N)c4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,26,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)c(C(C)C)c4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,71,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc5c(c4)OCC(c4ccccc4)NC5=O)c3c2)ccc1N1CCN(C)CC1,HPK1,active,45,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CC1=CNNN1c1ccc(-c2c[nH]c3ncc(-c4ccc(C5CCN(C)CC5)c(C#N)c4)cc23)cc1,HPK1,active,35,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)c(-c5ccccc5)c4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,76,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4cnc5c(c4)N(C)CCO5)c3c2)ccc1N1CCN(C)CC1,HPK1,active,12,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4cnc5c(c4)NCCO5)c3c2)ccc1N1CCN(C)CC1,HPK1,active,18,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2Cc2cnn(C)c2)CC1,HPK1,active,30,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4cc(F)c(C(=O)N(C)C)c(F)c4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,50,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)Nc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,91,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COCCN(C)c1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,59,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2F)CC1,HPK1,active,52,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)ccc1N(C)CCN(C)C,HPK1,active,84,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)ccc1N1CCCN(C)CC1,HPK1,active,31,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2[N+](=O)[O-])CC1,HPK1,active,60,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)ccc1N1CCCN(C)CC1,HPK1,active,19,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2C#N)CC1,HPK1,active,40,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CNC1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2)CC1,HPK1,active,76,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2c(F)cc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2F)CC1,HPK1,active,71,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(-c2c[nH]c3ncc(-c4ccc(CN5CCN(C)CC5)cc4)cc23)cc1,HPK1,active,16,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CC1=CNNN1c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)c(C)c4)cc23)cc1,HPK1,active,28,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cnnn1-c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)c(F)c4)cc23)cc1,HPK1,active,74,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cn4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,50,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2N2CC[C@@H](O)C2)CC1,HPK1,active,58,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2NCC2CCCO2)CC1,HPK1,active,72,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CNc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC6(COC6)C5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,32,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CNc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,12,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4cccc(C(=O)N(C)CCN(C)C)c4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,21,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4cccc(C(=O)N5CC(O)C5)c4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,60,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(OC5CNC5)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,27,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C5CC5)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,11,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CCNCC5)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,11,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4cccc(C(=O)N(C)C)c4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,89,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c(N5CCN(C)CC5)c(C)c4)cc23)ccc1C(=O)N(C)C,HPK1,active,35,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)c(Cl)c4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,36,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)c(F)c4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,32,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(-n5nncc5C)cc4)c3c2)cc(OC)c1N1CCN(C)CC1,HPK1,active,38,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCCN(C)CC5)c(C#N)c4)cc23)cc1,HPK1,active,23,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC(N(C)C)C6)cc5)c4c3)cc2C#N)CC1,HPK1,active,24,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC(O)C6)cc5)c4c3)cc2C#N)CC1,HPK1,active,35,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC7(COC7)C6)cc5)c4c3)cc2C#N)CC1,HPK1,active,32,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCN(C)C(=O)c1coc(-c2c[nH]c3ncc(-c4ccc(C5CCN(C)CC5)c(F)c4)cc23)n1,HPK1,active,32,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4nc(C(=O)N(C)CCN(C)C)co4)c3c2)ccc1C1CCN(C)CC1,HPK1,active,29,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4nc(C(=O)N(C)C)co4)c3c2)ccc1C1CCN(C)CC1,HPK1,active,92,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4nc(C(=O)N(C)C)co4)c3c2)cc(C)c1N1CCN(C2CCN(C)CC2)CC1,HPK1,active,24,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4nc(C(=O)N(C)C)co4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,49,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4nc(C(=O)N(C)CCN(C)C)co4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,45,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@@H](C)O)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,active,20,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4nc(C(=O)N(C)CCN(C)C)co4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,12,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4nc(C(=O)N5CC6(COC6)C5)co4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,58,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4nc(C(=O)N5CC(O)C5)co4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,55,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4nc(C(=O)N(C)C)co4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,19,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(CC(=O)N(C)c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC7(COC7)C6)cc5)c4c3)cc2)CC1,HPK1,active,27,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(CC(=O)N(C)c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2)CC1,HPK1,active,25,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ncc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cn2)CC1,HPK1,active,20,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1CN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2)C[C@@H](C)O1,HPK1,active,58,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2)C[C@@H](C)O1,HPK1,active,56,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(-c5ccccn5)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,active,55,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(Cc5ccc(C(=O)N(C)C)cc5)c4c3)cc2)CC1,HPK1,active,88,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(S(=O)(=O)N(C)C)cc5)c4c3)cc2)CC1,HPK1,active,47,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(S(=O)(=O)C6CC6)cc5)c4c3)cc2)CC1,HPK1,active,16,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc([C+2](=O)(=O)CO)cc5)c4c3)cc2)CC1,HPK1,active,12,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CCS(=O)(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,active,16,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CCS(=O)(=O)NC(C)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,active,46,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(NS(=O)(=O)C6CCCC6)cc5)c4c3)cc2)CC1,HPK1,active,69,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CCCS(=O)(=O)Nc1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,active,66,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(NS(=O)(=O)C6CC6)cc5)c4c3)cc2)CC1,HPK1,active,23,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(NS(C)(=O)=O)cc5)c4c3)cc2)CC1,HPK1,active,12,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(NC(=O)N(C)C)cc5)c4c3)cc2)CC1,HPK1,active,16,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)Nc1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,active,10,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CC(=O)N(C)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,active,63,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(-c6ncco6)cc5)c4c3)cc2)CC1,HPK1,active,53,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(C(=O)N(C)C)ccc1-c1c[nH]c2ncc(-c3ccc(N4CCN(C)CC4)cc3)cc12,HPK1,active,17,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C6CCCCN6)cc5)c4c3)cc2)CC1,HPK1,active,10,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(Cc2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4n3)cc2)CC1,HPK1,active,43,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4n3)cc2)C[C@@H](C)O1,HPK1,active,54,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5c(F)cc(C(=O)N(C)C)cc5F)c4n3)cc2)CC1,HPK1,active,23,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(OCC(=O)N(C)C)nc5)c4n3)cc2)CC1,HPK1,active,36,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(=O)n(CCC(=O)N(C)C)c5)c4n3)cc2)CC1,HPK1,active,11,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(=O)n(CC(=O)N(C)C)c5)c4n3)cc2)CC1,HPK1,active,40,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCOc1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)nc23)cn1,HPK1,active,31,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(OCCC(=O)N(C)C)cc5)c4n3)cc2)CC1,HPK1,active,38,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)N(C)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)nc23)cc1,HPK1,active,48,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCNC(=O)Nc1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)nc23)cc1,HPK1,active,14,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(NC(=O)N(C)C)cc5)c4n3)cc2)CC1,HPK1,active,37,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CC(=O)Nc1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)nc23)cc1,HPK1,active,18,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(S(=O)(=O)N(C)C)cc5)c4n3)cc2)CC1,HPK1,active,88,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(-c6ncco6)cc5)c4n3)cc2)CC1,HPK1,active,47,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(NS(C)(=O)=O)cc5)c4n3)cc2)CC1,HPK1,active,19,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CCN(CC)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)nc23)cc1,HPK1,active,22,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(S(C)(=O)=O)cc5)c4n3)cc2)CC1,HPK1,active,12,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5cnc(C(=O)N(C)C)nc5)c4n3)cc2)CC1,HPK1,active,49,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC7(COC7)C6)cc5)c4c3)cc2C#N)CC1,HPK1,active,97,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)c(C)c1N1CCN(C)CC1,HPK1,active,89,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(CCc5ccc(C(=O)N(C)C)cc5)c4c3)cc2)CC1,HPK1,active,46,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]c(Cl)c(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2)CC1,HPK1,active,43,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CCn1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3n2)cn1,HPK1,active,65,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(-c2c[nH]c3ncc(-c4cnc(N5CCN(C)CC5)nc4)cc23)cc1,HPK1,active,10,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)Cc1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)nc23)cc1,HPK1,active,10,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCC(=O)Nc1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)nc23)cc1,HPK1,active,12,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(NC(=O)CCCN6CCCC6)cc5)c4n3)cc2)CC1,HPK1,active,22,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)CCCN6CCCC6)cc5)c4n3)cc2)CC1,HPK1,active,12,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COC1CN(C(=O)c2ccc(-c3c[nH]c4ncc(-c5ccc(N6CCN(C)CC6)cc5)nc34)cc2)C1,HPK1,active,12,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCN1CCN(C(=O)c2ccc(-c3c[nH]c4ncc(-c5ccc(N6CCN(C)CC6)cc5)nc34)cc2)CC1,HPK1,active,16,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)Nc1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,active,12,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC(N(C)C)C6)cc5)c4c3)cc2)CC1,HPK1,active,22,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC(C)(C)C6)cc5)c4c3)cc2)CC1,HPK1,active,19,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(CNC(=O)c2ccc(-c3c[nH]c4ncc(-c5ccc(N6CCN(C)CC6)cc5)cc34)cc2)CC1,HPK1,active,21,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)NC6CCOCC6)cc5)c4c3)cc2)CC1,HPK1,active,30,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)NC6CCC(O)C6)cc5)c4c3)cc2)CC1,HPK1,active,27,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCN1CCN(C(=O)c2ccc(-c3c[nH]c4ncc(-c5ccc(N6CCN(C)CC6)cc5)cc34)cc2)CC1,HPK1,active,32,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CCCCC6)cc5)c4c3)cc2)CC1,HPK1,active,15,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CNC(C)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,active,20,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CC(c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1)N1CCCC1,HPK1,active,36,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C6CCCN6C)cc5)c4c3)cc2)CC1,HPK1,active,21,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,active,57,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CC(c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1)N(C)C,HPK1,active,32,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5cnn(C)c5)c4n3)cc2)CC1,HPK1,active,11,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(N(C)C)cc5)c4c3)cc2)CC1,HPK1,active,17,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1Cl,HPK1,active,51,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CCOc1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,active,38,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)c1,HPK1,active,26,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(O)cc5F)c4c3)cc2)CC1,HPK1,active,14,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccccc5F)c4c3)cc2)CC1,HPK1,active,37,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(Cl)cc5)c4c3)cc2)CC1,HPK1,active,41,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccccc5)c4c3)cc2)CC1,HPK1,active,19,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(CCC(=O)NCC(C)(C)O)CC5)nc23)ccc1C(=O)N(C)C,HPK1,active,49,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)Nc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(C)CC5)nc23)ccc1C(=O)N(C)C,HPK1,active,75,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(CCC(=O)NCCO)CC5)nc23)ccc1C(=O)N(C)C,HPK1,active,52,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3n2)cc2c1CCN(CCC(=O)NC1CC1)C2,HPK1,active,22,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(CCC(=O)NCCCO)CC5)nc23)ccc1C(=O)N(C)C,HPK1,active,65,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3n2)cc2c1CN(CC(C)(C)O)CC2,HPK1,active,21,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@@H]5CCOC5)cc4)c3n2)cc2c1CN(C)CC2,HPK1,active,14,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
COCCCNC(=O)CCN1CCc2c(C)cc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)c(C)c5)c4n3)cc2C1,HPK1,active,82,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(CCC(=O)NC4CC4)CC5)nc23)ccc1C(=O)N(C)C,HPK1,active,37,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(CCC(=O)NCCN4CCN(C)CC4)CC5)nc23)ccc1C(=O)N(C)C,HPK1,active,85,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(CCC(=O)N[C@H]4CC[C@@H](O)CC4)CC5)nc23)ccc1C(=O)N(C)C,HPK1,active,54,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
COCCCN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(C)CC5)nc23)cc1,HPK1,active,17,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3n2)cc2c1CCN(CCN1CCC(C)(O)CC1)C2,HPK1,active,35,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@@H]5CCOC5)cc4)c3n2)cc2c1CCN(CCN1CCC(C)(O)CC1)C2,HPK1,active,39,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(CCC(=O)N[C@@H]4CCOC4)CC5)nc23)ccc1C(=O)N(C)C,HPK1,active,42,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3n2)cc2c1CN(C)CC2,HPK1,active,11,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)NCC(C)(C)O)cc4)c3n2)cc2c1CCN(C)C2,HPK1,active,65,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC6(COC6)C5)cc4)c3n2)cc2c1CCN(C)C2,HPK1,active,13,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@H](C)O)cc4)c3n2)cc2c1CCN(CCN1CCOCC1)C2,HPK1,active,45,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)CCC#N)cc4)c3n2)cc2c1CCN(C)C2,HPK1,active,16,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(CCC(=O)NCC4CC4)CC5)nc23)ccc1C(=O)N(C)C,HPK1,active,89,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(CCC(=O)N[C@H]4CC[C@H](O)C4)CC5)nc23)ccc1C(=O)N(C)C,HPK1,active,93,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(CCC(=O)N[C@H]4CCC[C@H]4O)CC5)nc23)ccc1C(=O)N(C)C,HPK1,active,68,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
COCCCNC(=O)CN1CCc2c(C)cc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)c(C)c5)c4n3)cc2C1,HPK1,active,74,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@@H]5CCOC5)cc4)c3n2)cc2c1CCN(CCN1CCOCC1)C2,HPK1,active,36,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(CCC(=O)N[C@@H]4CCCOC4)CC5)nc23)ccc1C(=O)N(C)C,HPK1,active,78,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3n2)cc2c1CCN(CCC(=O)NCCN1CCN(C)CC1)C2,HPK1,active,67,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3n2)cc2c1CCN(CCC(=O)N[C@H]1CC[C@H](O)CC1)C2,HPK1,active,65,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@@H]5CCOC5)cc4)c3n2)cc2c1CCN(C)C2,HPK1,active,19,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(CCC(=O)NCC4(O)CC4)CC5)nc23)ccc1C(=O)N(C)C,HPK1,active,71,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(CCC(=O)NC4(CO)CC4)CC5)nc23)ccc1C(=O)N(C)C,HPK1,active,53,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(CCC(=O)NC4CCOCC4)CC5)nc23)ccc1C(=O)N(C)C,HPK1,active,67,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(CCC(=O)NC[C@@H](C)O)CC5)nc23)ccc1C(=O)N(C)C,HPK1,active,46,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(CCC(=O)NC[C@H](C)O)CC5)nc23)ccc1C(=O)N(C)C,HPK1,active,63,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(NC(=O)CCN2CCc3c(C)cc(-c4cnc5c(n4)C(c4ccc(C(=O)N(C)C)c(C)c4)CN5)cc3C2)cc1,HPK1,active,26,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(CCC(=O)N(C)C)CC5)nc23)ccc1C(=O)N(C)C,HPK1,active,63,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)CCN1CCc2c(C)cc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)c(C)c5)c4n3)cc2C1,HPK1,active,49,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(CCC(=O)N4CCN(C)CC4)CC5)nc23)ccc1C(=O)N(C)C,HPK1,active,75,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@H](C)O)c(C)c4)c3n2)cc2c1CCN(C)C2,HPK1,active,52,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@@H](C)O)cc4)c3n2)cc2c1CCN(CCN1CCOCC1)C2,HPK1,active,62,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(C)CC5)nc23)ccc1C(=O)N1CC(O)C1,HPK1,active,24,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
CN[C@H]1CCN(C(=O)c2ccc(-c3c[nH]c4ncc(-c5cc(C)c6c(c5)CN(C)CC6)nc34)cc2)C1,HPK1,active,12,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(C)CC5)nc23)ccc1C(=O)N(C)C[C@H](C)O,HPK1,active,74,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4cc(F)c(C(=O)N(C)C[C@@H]5CCOC5)c(F)c4)c3n2)cc2c1CN(C)CC2,HPK1,active,31,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4cc(F)c(C(=O)N(C)C[C@H]5CCOC5)c(F)c4)c3n2)cc2c1CN(C)CC2,HPK1,active,34,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@@H](C)O)cc4)c3n2)cc2c1CCN(C)C2,HPK1,active,36,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@H](C)O)cc4)c3n2)cc2c1CCN(C)C2,HPK1,active,21,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(C)CC5)nc23)ccc1C(=O)N(C)C[C@@H](C)O,HPK1,active,92,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc2c1C(C)(C)CN(C)C2,HPK1,active,36,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)CCN(C)C)cc4)c3c2)cc2c1CCN(C)C2,HPK1,active,14,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(-n5nncc5C)cc4)c3c2)cc2c1CN(C)CC2,HPK1,active,56,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@H](C)O)cc4)c3c2)cc2c1CCN(C)C2,HPK1,active,19,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)CC5CCOC5)cc4)c3c2)cc2c1CN(C)CC2,HPK1,active,52,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@@H](C)O)cc4)c3c2)cc2c1CN(C)CC2,HPK1,active,37,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
C=C(c1ccc(-c2c[nH]c3ncc(-c4cc5c(c(C(C)C)c4)CCN(C)C5)cc23)cc1)N(C)C,HPK1,active,17,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@H](C)O)cc4)c3c2)cc2c1CN(C)CC2,HPK1,active,15,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)CC5CCOC5)cc4)c3c2)cc2c1CCN(C)C2,HPK1,active,41,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc2c1CCN(CCN(C)C)C2,HPK1,active,49,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc2c1CCN(C)C2,HPK1,active,15,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc2c1CCN(C1CCCOC1)C2,HPK1,active,73,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc2c1CCN(C1CCC(C)(O)CC1)C2,HPK1,active,43,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc2c1CCN([C@H]1CC[C@](C)(O)CC1)C2,HPK1,active,45,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(C)CC5)cc23)ccc1C(=O)N(C)C,HPK1,active,15,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc2c1CCN(CCN1CCOCC1)C2,HPK1,active,35,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC2(CC1)COc1cc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)ccc12,HPK1,active,30,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(N2CCc3cc(-c4cnc5[nH]cc(-c6ccc(C(O)C7CN(C)C7)cc6)c5c4)ccc3C2)CC1,HPK1,active,21,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(n2c(=O)[nH]c3cc(-c4cnc5[nH]cc(-c6ccc(C(=O)N(C)C)cc6)c5c4)ccc32)CC1,HPK1,active,52,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(C2=CC=C(c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)C3C=NNC23)CC1,HPK1,active,47,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc2c1CN(C)CC2,HPK1,active,37,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC(O)C5)cc4)c3c2)cc2c1CN(C)CCO2,HPK1,active,45,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCc2cc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC(N(C)C)C6)cc5)c4c3)ccc2C1,HPK1,active,81,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCc2cc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)ccc2C1,HPK1,active,72,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCc2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC(N(C)C)C6)cc5)c4c3)cc2C1,HPK1,active,16,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCc2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC(O)C6)cc5)c4c3)cc2C1,HPK1,active,29,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)OCCN1CCc2c(C)cc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2C1,HPK1,active,63,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@@H](C)O)cc4)c3c2)cc2c1CCN(C)C2,HPK1,active,36,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc2c1CCN(CCNC(=O)C1CC1)C2,HPK1,active,27,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@@H](C)O)cc4)c3c2)cc2c1CCN(C)C2,HPK1,active,25,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@@H]5CCOC5)cc4)c3c2)cc2c1CN(C)CC2,HPK1,active,14,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@@H]5CCOC5)cc4)c3c2)cc2c1CCN(C)C2,HPK1,active,12,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc2c1CN(C1CCN(C)CC1)CC2,HPK1,active,18,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc2c1CCN(C1CCOCC1)C2,HPK1,active,37,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc2c1CCNC2,HPK1,active,21,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc2c1CN(C)C2,HPK1,active,52,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc5c(c4)CN(CCc4ncc[nH]4)CC5)cc23)cc1,HPK1,active,26,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc2c1CN(C)CC2,HPK1,active,36,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc2c1CN(C)CCO2,HPK1,active,38,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCc2cc(-c3cnc4[nH]cc(-c5ccc(C(O)C6CN(C)C6)cc5)c4c3)ccc2C1,HPK1,active,42,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)CCN1CCc2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2C1,HPK1,active,63,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCc2cc(-c3cnc4[nH]cc(-c5ccc6c(c5)CCN(C)C6=O)c4c3)ccc2C1,HPK1,active,43,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(N2CCc3cc(-c4cnc5[nH]cc(-c6ccc(C(=O)N(C)C)cc6)c5c4)ccc3C2)CC1,HPK1,active,67,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc5c(c4)CCN(C)C5)cc23)cc1,HPK1,active,53,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCc2cc(-c3cnc4[nH]cc(-c5ccc(C(=O)C6CC(O)C6)cc5)c4c3)ccc2C1,HPK1,active,91,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc5c(c4)CN(C)CC5)cc23)cc1,HPK1,active,50,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCc2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC7(COC7)C6)cc5)c4c3)cc2C1,HPK1,active,73,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCc2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2C1,HPK1,active,78,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CC[C@H]4CN(C)CCN54)nc23)ccc1C(=O)N(C)CC(C)(C)O,HPK1,active,96,ic50,WO_2021013083_A1, not Ki or Kd; not used in NCI fingerprint analysis
C=C(c1ccc(-c2c[nH]c3ncc(C4=CC5CCC6CN(C)CCN6C5C(C)=C4)nc23)cc1)N(C)CC(C)(C)O,HPK1,active,52,ic50,WO_2021013083_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)CC(C)(C)O)cc4)c3n2)cc2c1N1CCN(C)C[C@H]1CC2,HPK1,active,52,ic50,WO_2021013083_A1, not Ki or Kd; not used in NCI fingerprint analysis
C=C(c1ccc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CC[C@H]4CN(C)CCN54)nc23)cc1C)N(C)C[C@@H]1CCOC1,HPK1,active,53,ic50,WO_2021013083_A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1=CC(c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@@H]5CCOC5)c(C)c4)c3n2)=CC2CC[C@@H]3CN(C)CCN3C12,HPK1,active,52,ic50,WO_2021013083_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@H]5CCOC5)cc4)c3n2)cc2c1N1CCN(C)C[C@H]1CC2,HPK1,active,17,ic50,WO_2021013083_A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1=CC(c2cnc3[nH]cc(-c4ccc(C(=O)N(C)CC5CCOC5)cc4)c3n2)=CC2CCC3CN(C)CCN3C12,HPK1,active,17,ic50,WO_2021013083_A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1=CC(c2cnc3[nH]cc(-c4ccc(C(=O)N5CC6(COC6)C5)cc4)c3n2)=CC2CC[C@H]3CN(C)CCN3C12,HPK1,active,21,ic50,WO_2021013083_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@@H]5CCOC5)cc4)c3c2)cc2c1N1CCN(C)C[C@H]1CC2,HPK1,active,14,ic50,WO_2021013083_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@@H](C)O)cc4)c3c2)cc2c1N1CCN(C)C[C@@H]1CC2,HPK1,active,18,ic50,WO_2021013083_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@@H](C)O)cc4)c3c2)cc2c1N1CCN(C)C[C@H]1CC2,HPK1,active,21,ic50,WO_2021013083_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@H](C)O)cc4)c3c2)cc2c1N1CCN(C)C[C@@H]1CC2,HPK1,active,19,ic50,WO_2021013083_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@H](C)O)cc4)c3c2)cc2c1N1CCN(C)C[C@H]1CC2,HPK1,active,14,ic50,WO_2021013083_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc2c1N1CCN(C)CC1CC2,HPK1,active,31,ic50,WO_2021013083_A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1=CC(c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3n2)=CC2CC[C@@H]3CN(C)CCN3C12,HPK1,active,23,ic50,WO_2021013083_A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1=CC(c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3n2)=CC2CC[C@H]3CN(C)CCN3C12,HPK1,active,22,ic50,WO_2021013083_A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1=CC(c2cnc3[nH]cc(-c4ccc(C(=O)N5CC6(COC6)C5)c(C)c4)c3n2)=CC2CC[C@@H]3CN(C)CCN3C12,HPK1,active,58,ic50,WO_2021013083_A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1=CC(c2cnc3[nH]cc(-c4ccc(C(=O)N5CC6(COC6)C5)c(C)c4)c3n2)=CC2CC[C@H]3CN(N)CCN3C12,HPK1,active,61,ic50,WO_2021013083_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@@H]5CCOC5)cc4)c3c2)cc2c1N1CCN(C)C[C@@H]1CC2,HPK1,active,15,ic50,WO_2021013083_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@H]5CCOC5)cc4)c3c2)cc2c1N1CCN(C)C[C@H]1CC2,HPK1,active,32,ic50,WO_2021013083_A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@H]5CCOC5)cc4)c3c2)cc2c1N1CCN(C)C[C@@H]1CC2,HPK1,active,27,ic50,WO_2021013083_A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1=CC(c2cnc3[nH]cc(-c4ccc(C(=O)N5CC6(COC6)C5)cc4)c3n2)=CC2CC[C@@H]3CN(C)CCN3C12,HPK1,active,17,ic50,WO_2021013083_A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1=CC(c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)c(C)c4)c3n2)=CC2CC[C@@H]3CN(C)CCN3C12,HPK1,active,36,ic50,WO_2021013083_A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1=CC(c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)c(C)c4)c3n2)=CC2CC[C@H]3CN(C)CCN3C12,HPK1,active,47,ic50,WO_2021013083_A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3P(C)(C)=O)n1)CN(C1COC1)CC2,HPK1,active,10,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
CP(C)(=O)c1ccccc1Nc1nc(Nc2cc3c(cc2C(F)(F)F)CCNC3)ncc1Cl,HPK1,active,10,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
CCOc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3P(C)(C)=O)n1)CN(C)CC2,HPK1,active,10,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3P(C)(C)=O)n1)C(C)(C)N(C)CC2,HPK1,active,10,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(F)c(Nc3ccccc3P(C)(C)=O)n1)CN(C)CC2,HPK1,active,10,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3P(C)(C)=O)n1)CC(N(C)C)C2,HPK1,active,10,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3P(C)(C)=O)n1)[C@H](N(C)C)CCC2,HPK1,active,10,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
COc1c(Nc2ncc(Cl)c(Nc3ccccc3P(C)(C)=O)n2)cc2c(c1N)CC1CCCCN1C2,HPK1,active,10,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3P(C)(C)=O)n1)CCN(C)CC2,HPK1,active,10,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3P(C)(C)=O)n1)CN(C)C2,HPK1,active,10,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
Nc1c(-c2nc3ccc(N4CC5CCC4CN5)nc3[nH]2)c(=O)[nH]c2sccc12,HPK1,active,33,ic50,CN109721620A_Original_document_20201120095431, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N)c5ncsc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,32,ic50,CN109721620A_Original_document_20201120095431, not Ki or Kd; not used in NCI fingerprint analysis
CN1C2CCC1CC(c1ccc3nc(-c4c(N)c5ccsc5[nH]c4=O)[nH]c3n1)C2,HPK1,active,21,ic50,CN109721620A_Original_document_20201120095431, not Ki or Kd; not used in NCI fingerprint analysis
Nc1c(-c2nc3ccc(N4CCC5(CCC5)CC4)nc3[nH]2)c(=O)[nH]c2sccc12,HPK1,active,75,ic50,CN109721620A_Original_document_20201120095431, not Ki or Kd; not used in NCI fingerprint analysis
Nc1c(-c2nc3ccc(N4CC5(CNC5)C4)nc3[nH]2)c(=O)[nH]c2sccc12,HPK1,active,42,ic50,CN109721620A_Original_document_20201120095431, not Ki or Kd; not used in NCI fingerprint analysis
CN1CC2CCC1CN2c1ccc2nc(-c3c(N)c4ccsc4[nH]c3=O)[nH]c2c1,HPK1,active,30,ic50,CN109721620A_Original_document_20201120095431, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ccc3nc(-c4c(N)c5ccsc5[nH]c4=O)[nH]c3n2)CC1,HPK1,active,14,ic50,CN109721620A_Original_document_20201120095431, not Ki or Kd; not used in NCI fingerprint analysis
Nc1c(-c2nc3ccc(C4CCN(C5CC5)CC4)nc3[nH]2)c(=O)[nH]c2sccc12,HPK1,active,13,ic50,CN109721620A_Original_document_20201120095431, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)Nc1c(-c2nc3c([nH]2)C=C(N2CCN(C)CC2)CC3)c(=O)[nH]c2sccc12,HPK1,active,21,ic50,CN109721620A_Original_document_20201120095431, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(NS(C)(=O)=O)c5ccsc5[nH]c4=O)[nH]c3c2)CC1,HPK1,active,13,ic50,CN109721620A_Original_document_20201120095431, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(C(=O)C(C)(C)O)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3C4CC3CN(C(=O)N(C)C)C4)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC4(CC3)NC(=O)N(C)C4=O)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC(C(=O)NCCO)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC(C(=O)N4CCOCC4)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NC3(C#N)CN(S(=O)(=O)Cc4ccccc4)C3)cc2c1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NC3(C#N)CN(S(=O)(=O)C4CC4)C3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NC3(C#N)CN(Cc4ccccc4)C3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CC(C#N)C3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
CCn1cc(NC(=O)C(=O)Nc2cc3cc(-c4cnccc4C)cc(N)c3cn2)cn1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NCCCc3ccccc3)cc2c1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NCCC#N)cc2c1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3ccc(-c4ccccc4)nc3)cc2c1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)N3CCCCC3)cc2c1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NC(C)(C)C#N)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)N3CCNC(=O)C3)cc2c1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(C)c2cnc(NC(=O)C(=O)NCc3ccccn3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(C)c2cnc(NC(=O)C(=O)Nc3cccnc3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc2cc(NC(=O)C=C3CC4(C3)CN(C(=O)c3ccc(Cl)c(C(F)(F)F)c3)C4)ncc2c(N)n1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc2cc(NC(=O)C=C3CC4(C3)CN(C(=O)c3ccccc3)C4)ncc2c(N)n1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc2cc(NC(=O)C=C3CCC(C#N)(C#N)CC3)ncc2c(N)n1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc2cc(NC(=O)C=C3CC4(C3)CC(C#N)C4)ncc2c(N)n1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CC4(C3)CC(C#N)C4)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC(C#N)(C#N)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)C1CCC(=CC(=O)Nc2cc3cc(-c4cncc(N)c4C)ccc3cn2)CC1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(N)cncc1-c1ccc2cnc(NC(=O)C=C3CCC(C#N)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(N)cncc1-c1cc2cc(NC(=O)C=C3CCC(C#N)CC3)ncc2cc1F,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1ccc2cnc(NC(=O)C=C3CCC(C#N)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(N)cncc1-c1cc(Cl)c2cnc(NC(=O)C=C3CCC(C#N)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCOCC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CC(C)(C)OC(C)(C)C3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(C(=O)C(=O)N(C)C)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)C(=O)N1CCC(=CC(=O)Nc2cc3cc(-c4cnccc4C)cc(N)c3cn2)CC1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)C1CCCN1C(=O)N1CCC(=CC(=O)Nc2cc3cc(-c4cnccc4C)cc(N)c3cn2)CC1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(C(=O)N4CCC(N)C4)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(C(=O)N4CCCC(N)C4)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3C(C)(C)CNCC3(C)C)cc2c1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3C(C)(C)CN(C(=O)[C@H](C)N)CC3(C)C)cc2c1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(N)cncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(S(=O)(=O)N(C)C)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1=C(N)CNC=C1c1cc(N)c2cnc(NC(=O)C=C3CCN(C(=O)c4cccnc4)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC(OC(=O)NO)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(N)cncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC(C(=O)N4CCOCC4)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(N)cncc1-c1cc(N)c2cnc(NC(=O)C=C3CC(C#N)C3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(C(=O)NOC(C)(C)C)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(N)cncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC4(CC3)C(=O)N(C)C(=O)N4C)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(C(=O)[C@@H]4CCCN4C)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(C(=O)[C@@H]4CCCN4)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(N)cncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC(C#N)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(C(=O)NO)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(C(=N)N)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(c4ncccn4)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(C(=O)c4ccccn4)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(C(=O)c4ccncc4)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(C(=O)c4cccnc4)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3C4CC3CN(S(=O)(=O)N(C)C)C4)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3C4CC3CN(S(C)(=O)=O)C4)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(c4nccs4)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(C(=O)C(C)(C)N)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(S(N)(=O)=O)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(C(=O)[C@@H](N)CC(C)C)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(C(=O)N4CCN(C)CC4)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(C(=O)NC4CC4)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC4(CC3)C(=O)NC(=O)N4C)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(C(=O)[C@@H](N)Cc4ccccc4)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(C(=O)CN)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(S(=O)(=O)N(C)C)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
CNS(=O)(=O)N1CCC(=CC(=O)Nc2cc3cc(-c4cnccc4C)cc(N)c3cn2)CC1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(C(=O)NCC(F)(F)F)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(S(C)(=O)=O)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC(O)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(S(=O)(=O)c4cccc(C#N)c4)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(C(=O)Nc4ccccc4)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(C(=O)c4ccccc4)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCC(=CC(=O)Nc2cc3cc(-c4cnccc4C)cc(N)c3cn2)CC1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC(CO)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC(C(=O)NCC(C)(C)O)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(C(=O)C(C)N)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc2cc(NC(=O)C=C3CCC(C#N)CC3)ncc2c(N)n1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(C(=O)N4CCOCC4)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC(C(=O)N4CCCCC4)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC(C(=O)Nc4ccccc4)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC(C(=O)NCCC#N)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(C(=O)OC(C)(C)C)CC3)cc2c1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC(CCC#N)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC(CC#N)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc2cc(NC(=O)C=C3CC(C#N)C3)ncc2c(N)n1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC(C(=O)N4CCN(C)CC4)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC(C(=O)N4CCNCC4)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(C(=O)N(C)C)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC(C(=O)NC4CC4)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC(C(=O)O)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC4(CC3)C(=O)N(C)C(=O)N4C)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC(c4cnn(C)c4)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC(C(=O)NC4CCC4)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC(C(=O)N4CCCC4)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(C(N)=O)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)N1CCC(=CC(=O)Nc2cc3cc(-c4cnccc4C)cc(N)c3cn2)CC1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)N1CCC(=CC(=O)Nc2cc3cc(-c4cnccc4C)cc(N)c3cn2)CC1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC(F)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC(C(=O)N(C)C)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)C1CCC(=CC(=O)Nc2cc3cc(-c4cnccc4C)cc(N)c3cn2)CC1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC(C(N)=O)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(F)=C3CC(C#N)C3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(F)=C3CCC(C#N)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C(=O)Nc1cc2cc(-c3cnccc3C)cc(N)c2cn1)=C1CC(C#N)C1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
CCSC1CCC(=CC(=O)Nc2cc3cc(-c4cnccc4C)cc(N)c3cn2)CC1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CC(C)(C#N)C3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOC1CCC(=CC(=O)Nc2cc3cc(-c4cnccc4C)cc(N)c3cn2)CC1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCS(=O)(=O)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCSCC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC(C#N)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC(F)(F)CC3)cc2c1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
CCS(=O)(=O)N1CC(CC#N)(NC(=O)C(=O)Nc2cc3cc(-c4cnccc4C)cc(N)c3cn2)C1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NC3(C#N)CN(CC4CC4)C3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)/C=C/CN(C)C)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCCC3)cc2c1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
CCS(=O)(=O)N1CC/C(=C/C(=O)Nc2cc3cc(-c4cnccc4C)cc(N)c3cn2)C1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
CCS(=O)(=O)N1CCC(=CC(=O)Nc2cc3cc(-c4cnccc4C)cc(N)c3cn2)CC1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCCCC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCN(C)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3CCNCC3)cc2c1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)/C=C/c3ccc4c(c3)OCO4)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)/C=C/c3ccccc3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)N[C@H]3CC[C@H](C(N)=O)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)/C=C/C(=O)N3CCCC3)cc2c1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)/C=C/C(=O)NCC3CC3)cc2c1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3cnn(CC(C)(C)O)c3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)N[C@H]3CC[C@@H](C(N)=O)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)/C=C/C(=O)NCc3ccccc3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NC3(C#N)CN(Cc4ccc(C#N)cc4)C3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
CCS(=O)(=O)N1CC(C#N)(NC(=O)C(=O)Nc2cc3cc(-c4cnccc4C)cc(N)c3cn2)C1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)/C=C/C(=O)Nc3ccccc3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3ccc(C(C)(C)C)cc3Br)cc2c1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3ccc(C(C)C)cc3)cc2c1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NC3(C#N)CNC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
CCS(=O)(=O)NCCn1cc(NC(=O)C(=O)Nc2cc3cc(-c4cnccc4C)cc(N)c3cn2)cn1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)/C=C/C(=O)N3CCOCC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NCc3ccccc3C(F)(F)F)cc2c1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(C)cc1NC(=O)C(=O)Nc1cc2cc(-c3cnccc3C)cc(N)c2cn1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3c(C)cccc3C)cc2c1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3ccc(F)c(C(F)(F)F)c3)cc2c1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3ccccc3C#N)cc2c1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)/C=C/C(=O)Nc3ccc(CC#N)cc3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)/C=C/C(=O)N3CCCCC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)/C=C/C(=O)Nc3cnn(C)c3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NCC#N)cc2c1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3cnn(S(=O)(=O)CC(C)C)c3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3cnn(S(=O)(=O)c4cccnc4)c3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3cnn(S(=O)(=O)c4cccc(C#N)c4)c3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(S(=O)(=O)n2cc(NC(=O)C(=O)Nc3cc4cc(-c5cnccc5C)cc(N)c4cn3)cn2)cc1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3cnn(S(=O)(=O)C4CC4)c3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3cnn(CC4CC4)c3)cc2c1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NC3CCN(C)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NC3CCOCC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NC3(C#N)CCOC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NC3(C#N)CCCC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3cnn(C(C)C)c3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NC3CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3cnn(CCC#N)c3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3cnn(CC#N)c3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NC3(C#N)CCOCC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NC3(C#N)COC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NC3(C#N)CCC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3ccc(C#N)cc3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3ccc4ncccc4c3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3ccc(CC#N)cc3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)N3CCC(C#N)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NC(C)(C)CC#N)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)c1ccc(C2(NC(=O)C(=O)Nc3cc4cc(-c5cnccc5C)cc(N)c4cn3)CC2)cc1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NCc3cccc(C#N)c3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3cccc(C#N)c3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NCCc3c[nH]c4ccccc34)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)N3CCn4c(nnc4C(F)(F)F)C3)cc2c1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NC3(C#N)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NCc3ccc(C#N)cc3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NCc3cc4ccccc4[nH]3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3cnn(Cc4ccccc4)c3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3cncc(-c4ccccc4)c3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)N(C)c3ccccc3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NCc3cccc(C(F)(F)F)c3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(CNC(=O)C(=O)Nc2cc3cc(-c4cnccc4C)cc(N)c3cn2)c(OC)c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NCc3ccccc3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3cnn(CCOCCN)c3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3cccc(-c4ccccc4)c3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NN3CCCCC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)NOCc3ccccc3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)NN3CCCCC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)NNc3ccccc3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3nc4c(s3)CCC4)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)N3CCN(C)CC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)NN3CCOCC3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc2cc(NC(=O)C(=O)Nc3ccccc3)ncc2c(N)n1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3cn[nH]c3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
CCS(=O)(=O)n1cc(NC(=O)C(=O)Nc2cc3cc(-c4cnccc4C)cc(N)c3cn2)cn1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
COCCn1cc(NC(=O)C(=O)Nc2cc3cc(-c4cnccc4C)cc(N)c3cn2)cn1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NCc3cccnc3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3ccncc3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(NC(=O)C(=O)Nc2cc3cc(-c4cnccc4C)cc(N)c3cn2)on1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3cnn(C)c3)cc2c1,HPK1,active,10,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(N)c3nnc(Nc4cc5n(n4)CS(=O)(=O)N(C)C5)cc3c2)cnc2c1NCCO2,HPK1,active,90,ec50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)[C@H]1COC(=O)N1c1cc(N)c2nnc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)cc2c1,HPK1,active,44,ec50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c([C@H]2C[C@@H]2C(=O)Nc2cc3cc(N4C(=O)OC[C@@H]4C)cc(N)c3nn2)cnn1C,HPK1,active,44,ec50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1COC(=O)N1c1cc(N)c2nnc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)cc2c1,HPK1,medium,132,ec50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2nnc(NC(=O)N3CC(c4cnn(C)c4)C3)cc2c1,HPK1,active,53,ic50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1cc([C@H]2C[C@@H]2C(=O)Nc2cc3cc(-c4c(F)cccc4Cl)cc(N)c3nn2)cn1,HPK1,active,38,ec50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(N)cncc1-c1cc(N)c2nnc(NC(=O)OC3CCOCC3)cc2c1,HPK1,active,35,ic50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc2cc(NC(=O)C3CC3)nnc2c(N)n1,HPK1,active,53,ec50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnn4ccccc34)ncc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4ccc(N5CCO[C@H](C(C)(C)O)C5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc2c(-c3ccc(Nc4ccc(CN5CCOCC5)cn4)c4c3CNC4=O)cnn2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccn2c(-c3ccc(Nc4ccc(CN5CCOCC5)cn4)c4c3CNC4=O)cnc2c1F,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccn2c(-c3ccc(Nc4ccc(N5CCO[C@@H](C(C)(C)O)C5)cn4)c4c3CNC4=O)cnc2c1F,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)[C@@H]1CN(c2ccc(Nc3cnc(-c4cnc5c(F)cccn45)c4c3C(=O)NC4)nc2)CCO1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)[C@@H]1CN(c2ccc(Nc3cnc(-c4cnc5c(Cl)cccn45)c4c3C(=O)NC4)nc2)CCO1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)[C@@H]1CCCN(c2ccc(Nc3cnc(-c4cnc5c(O)cccn45)c4c3C(=O)NC4)nc2)C1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccn2c(-c3ccc(Nc4ccc(N5CCO[C@H](CO)C5)cn4)c4c3CNC4=O)cnc2c1F,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)[C@H]1CN(c2ccc(Nc3ccc(-c4cnc5cnccn45)c4c3C(=O)NC4)nc2)CCO1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccn2c(-c3ccc(Nc4ccc(C(C)(C)C(=O)NCCN(C)C)cn4)c4c3CNC4=O)cnc2c1F,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccn2c(-c3ccc(Nc4ccc(N5CCO[C@@H](CO)C5)cn4)c4c3CNC4=O)cnc2n1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2cccc(Nc3cnc(-c4cnc5ccccn45)c4c3C(=O)NC4)n2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3ccc(N4CCO[C@@H](CO)C4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CNC1CCN(c2ccc(Nc3cnc(-c4ccnc5c4ccn5C)c4c3C(=O)NC4)nc2)CC1(F)F,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3ccc(N4CCO[C@H](CO)C4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CNC1CN(c2cccc(Nc3cnc(-c4ccnc5c4ccn5C)c4c3C(=O)NC4)n2)C1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(Cl)ccn34)ccc(Nc3ccc(N4CCC(O)(CN5CCOCC5)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnn4c3CCCC4)ccc(Nc3ccc(N4CCC[C@@]5(CCNC5=O)C4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccn2c(-c3ccc(Nc4ccc(N5CCC(O)(CN6CCN(C)CC6)CC5)cn4)c4c3CNC4=O)cnc2c1F,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccn2c(-c3ccc(Nc4ccc(N5CCC(O)(CN6CCOCC6)CC5)cn4)c4c3CNC4=O)cnc2c1F,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
COCC1(O)CCN(c2ccc(Nc3ccc(-c4cnc5cc(F)ccn45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(CC2(O)CCN(c3ccc(Nc4ccc(-c5cnc6cc(Cl)ccn56)c5c4C(=O)NC5)nc3)CC2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(CO)CCN(c2ccc(Nc3ccc(-c4cnc5cc(F)ccn45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(N2CCOCC2)CCN(c2ccc(Nc3ccc(-c4cnc5cc(F)ccn45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3ccc(N4CCC(CN5CCOCC5)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4ccc(C5(O)CCOCC5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cnc-2n1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1cc(-c2ccc(Nc3ccc(N4CCC(O)CC4)cn3)c3c2CNC3=O)c2cnncc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4ncc(N5CCC(O)CC5)cc4F)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4cccc(C5CNC5)n4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
COC[C@H]1CN(c2ccc(Nc3cnc(-c4ccnc5c4ccn5C)c4c3C(=O)NC4)nc2)CC[C@@H]1O,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(CC2(O)CCN(c3ccc(Nc4ccc(-c5cnc6cnccn56)c5c4C(=O)NC5)nc3)CC2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CC(c2ccn3c(-c4ccc(Nc5ccc(N6CCC(O)CC6)cn5)c5c4CNC5=O)cnc3c2)C1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1nc(Nc2ccc(-c3cnc4cc(F)ccn34)c3c2C(=O)NC3)cc1C1CCOCC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(O)(c2cccc(Nc3cnc(-c4ccnc5c4ccn5C)c4c3C(=O)NC4)n2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCN1CCC(c2ccc(Nc3ccc(-c4cnc5cc(F)ccn45)c4c3C(=O)NC4)nc2)CC1=O,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(CC2(O)CCN(c3ccc(Nc4ccc(-c5cnc6ccccn56)c5c4C(=O)NC5)nc3)CC2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cccn2c(-c3ccc(Nc4ccc(N5CCC(O)(CN6CCN(C)CC6)CC5)cn4)c4c3CNC4=O)cnc12,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(CC2(O)CCN(c3ccc(Nc4cnc(-c5ccnc6c5ccn6C)c5c4C(=O)NC5)nc3)CC2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(O)CCN(c2ccc(Nc3ccc(-c4cnc5cc(F)ccn45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ccc(Nc3cnc(-c4ccnc5c4ccn5C)c4c3C(=O)NC4)nc2)CC1=O,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3ccc(N4CC(O)CCC45CC5)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
COC[C@@]1(O)CCCN(c2ccc(Nc3ccc(-c4cnc5cc(F)ccn45)c4c3C(=O)NC4)nc2)C1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCN1CCC(c2ccc(Nc3cnc(-c4ccnc5c4ccn5C)c4c3C(=O)NC4)nc2)CC1=O,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CC1(O)CCCN(c2ccc(Nc3ccc(-c4cnc5cc(F)ccn45)c4c3C(=O)NC4)nc2)C1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(Nc2ccc(N3CCC(O)CC3)cn2)c2c(c1-c1cnc3cc(F)ccn13)CNC2=O,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3ccc(N4CCC(O)(CN5CCCC5)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CC1CN(c2ccc(Nc3ccc(-c4cnc5cc(F)ccn45)c4c3C(=O)NC4)nc2)CCO1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3cc(C4CCOCC4)[nH]n3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(Nc2ccc(-c3cnc4cc(F)ccn34)c3c2C(=O)NC3)ncc1N1CCC(O)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3ccc(C4(O)CCOCC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1cc(-c2ccc(Nc3ccc(N4CCC(O)CC4)cn3)c3c2CNC3=O)c2ccnnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1csc2c(-c3ncc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)ccnc12,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3ccc4cnccn34)ccc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnn4c3CCCC4)ncc(Nc3ccc(N4CCOCC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CC1(O)CCN(c2ccc(Nc3ccc(-c4cnc5cc(F)ccn45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(CC2(O)CCN(c3ccc(Nc4ccc(-c5cnc6cc(F)ccn56)c5c4C(=O)NC5)nc3)CC2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cnc-2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1csc2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)ccnc12,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)[C@@H]1CN(c2ccc(Nc3ccc(-c4cnc5cc(F)ccn45)c4c3C(=O)NC4)nc2)CCO1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3ccc(N4CCC(O)(CN5CCOCC5)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)[C@H]1CN(c2ccc(Nc3ccc(-c4cnc5cc(F)ccn45)c4c3C(=O)NC4)nc2)CCO1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4ccc(N5CCC(O)(CN6CCOCC6)CC5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4cnc5cnccn45)c4c3C(=O)NC4)nc2)CC1=O,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3ccc(C4CCOCC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CC[C@@H](c2ccc(Nc3ccc(-c4cnc5cc(F)ccn45)c4c3C(=O)NC4)nc2)C1=O,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1C[C@H](c2ccc(Nc3ccc(-c4cnc5cnccn45)c4c3C(=O)NC4)nc2)CC1=O,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1C[C@@H](c2ccc(Nc3ccc(-c4cnc5cnccn45)c4c3C(=O)NC4)nc2)CC1=O,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3ccc(N4CCOCC45CC5)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
COC[C@H]1CN(c2ccc(Nc3ccc(-c4cnc5cnccn45)c4c3C(=O)NC4)nc2)CCO1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
COC[C@@H]1CN(c2ccc(Nc3ccc(-c4cnc5cnccn45)c4c3C(=O)NC4)nc2)CCO1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cnccn34)ccc(Nc3ccc(N4CCC[C@H](O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cnccn34)ccc(Nc3ccc(N4CCC[C@@H](O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2cccc(Nc3cnc(-c4ccnc5c4ccn5C)c4c3C(=O)NC4)n2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1C[C@H](c2ccc(Nc3ccc(-c4cnc5cnccn45)c4c3C(=O)NC4)nc2)CCC1=O,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1C[C@@H](c2ccc(Nc3ccc(-c4cnc5cnccn45)c4c3C(=O)NC4)nc2)CCC1=O,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1NC(=O)c2c(Nc3ccc(N4CCC(O)CC4)cn3)ccc(-c3cnc4ccccn34)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3ccc(S(=O)(=O)CC4CCC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)N1CCN(c2ccc(Nc3cnc(-c4ccnc5c4ccn5C)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cnccn34)ccc(Nc3ccc(N4CC(O)C4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1COCCN1c1ccc(Nc2ccc(-c3cnc4cnccn34)c3c2C(=O)NC3)nc1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(O)CCN(c2ccc(Nc3ccc(-c4cnc5cnccn45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cnccn34)ccc(Nc3ccc(N4CC5(COC5)C4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)[C@H]1CCCN(c2ccc(Nc3ccc(-c4cnc5cnccn45)c4c3C(=O)NC4)nc2)C1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)[C@@H]1CCCN(c2ccc(Nc3ccc(-c4cnc5cnccn45)c4c3C(=O)NC4)nc2)C1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cnccn34)ccc(Nc3ccc(N4CCCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cnccn34)ccc(Nc3ccc(N4CCCOCC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4ccc(N5CCC6(CC5)COC6)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
COCC1(O)CCN(c2ccc(Nc3ccc(-c4ccnc5c4ccn5C)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1CCn2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cnc2C1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCc2cc(Nc3ccc(-c4ccnc5c4ccn5C)c4c3C(=O)NC4)nn2CC1=O,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4ccc(CS(C)(=O)=O)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4ccc(N5CC6(CC(O)C6)C5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(Nc2ccc(N3CCC(O)CC3)cn2)c2c(c1-c1cccc3c1ccn3C)CNC2=O,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(Nc2ccc(-c3ccnc4c3ccn4C)c3c2C(=O)NC3)ncc1N1CCC(O)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4ccc(N5CCC(O)(CN6CCOCC6)CC5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4ccc(N5CC[C@@H](O)C5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnn4c3CCCC4)ccc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cccc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4ccc(N5CC[C@H](O)C5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4ccc(N5CCCC(C(C)(C)O)C5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4ccc(N5CCOCC5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(C)(c2ccc(Nc3ccc(-c4ccnc5c4ccn5C)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4ccnc5c4ccn5CC(N)=O)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(O)(c2ccc(Nc3ccc(-c4ccnc5c4ccn5C)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4ccc(C5(C)CCNCC5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ccc(Nc3ccc(-c4ccnc5c4ccn5C)c4c3C(=O)NC4)nc2)CC1=O,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1CCn2ncc(-c3ccc(Nc4ccc(N5CCN(C)CC5)cn4)c4c3CNC4=O)c2C1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4ccc(N5CC6CCC(C5)N6)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4ccc(N5CCNCC5)cn4)c4c3CNC4=O)cccc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4ccnc5c4ccn5C4CC4)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1COc2c(-c3ccc(Nc4ccc(N5CCN(C)CC5)cn4)c4c3CNC4=O)cnn2C1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3cnc(-c4cnn5c4CCCC5)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4ccc(N5CCNCC5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4ccn5ncccc45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3cnc(-c4cccc5c4ccn5C)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2cccc(Nc3ccc(-c4ccnc5c4ccn5C)c4c3C(=O)NC4)n2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCN(C)c1cccc(Nc2cnc(-c3ccnc4c3ccn4C)c3c2C(=O)NC3)n1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN[C@@H]1CCN(c2cccc(Nc3cnc(-c4ccnc5c4ccn5C)c4c3C(=O)NC4)n2)C1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CNC1(C)CCN(c2ccc(Nc3cnc(-c4ccnc5c4ccn5C)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)[C@H]1CCCN(c2ccc(Nc3cnc(-c4cnc5c(F)cccn45)c4c3C(=O)NC4)nc2)C1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4c(O)c(F)ccn34)ccc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cccn2c(-c3ncc(Nc4ccc(N5CCC[C@@H](C(C)(C)O)C5)cn4)c4c3CNC4=O)cnc12,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3ccc(CN4CCOCC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4cccc(N5CCNCC5)n4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4cccc(N5CCC[C@H](N)C5)n4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2cccc(Nc3ccc(-c4cnc5cc(Cl)ccn45)c4c3C(=O)NC4)n2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
COCCN(C)c1ccc(Nc2ccc(-c3cnc4cc(F)ccn34)c3c2C(=O)NC3)nc1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccn2c(-c3ccc(Nc4ccc(N5CCC[C@H](C(C)(C)O)C5)cn4)c4c3CNC4=O)cnc2n1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2cccc(Nc3ccc(-c4cnc5cc(F)ccn45)c4c3C(=O)NC4)n2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(-c3ncc(Nc4ccc(N5CCC[C@@H](C(C)(C)O)C5)cn4)c4c3CNC4=O)ccnc2n1C,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)C1CCN(c2ccc(Nc3ccc(-c4cnc5cc(F)ccn45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCNC(=O)C(C)(C)c1ccc(Nc2ccc(-c3cnc4cc(F)ccn34)c3c2C(=O)NC3)nc1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4ccc(N5CCC[C@H](C(C)(C)O)C5)cn4)c4c3CNC4=O)cccc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3ccc([C@H]4CCOC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccn2c(-c3ccc(Nc4ccc(N5CCC[C@@H](C(C)(C)O)C5)cn4)c4c3CNC4=O)cnc2n1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4ccc(N5CCOCC5)cn4)c4c3CNC4=O)cccc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4ccc(N5CCC[C@@H](C(C)(C)O)C5)cn4)c4c3CNC4=O)cccc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)[C@H]1CCCN(c2ccc(Nc3cnc(-c4cnc5ccccn45)c4c3C(=O)NC4)nc2)C1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H](O)C1CCN(c2ccc(Nc3ccc(-c4cnc5cc(F)ccn45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4ccc([C@H]5CCOC5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3ccc([C@@H]4CCOC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4ccc([C@@H]5CCOC5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)[C@H]1CCCN(c2ccc(Nc3ccc(-c4cnc5cc(F)ccn45)c4c3C(=O)NC4)nc2)C1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4ccc(N5CCC[C@H](C(C)(C)O)C5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4ccc(N5CCC[C@@H](C(C)(C)O)C5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)[C@@H]1CCCN(c2ccc(Nc3cnc(-c4cnc5ccccn45)c4c3C(=O)NC4)nc2)C1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(F)ccn2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cnc12,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)[C@@H]1CCCN(c2ccc(Nc3ccc(-c4cnc5cc(F)ccn45)c4c3C(=O)NC4)nc2)C1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(OCCO)ccn34)ccc(Nc3ccc(N4CCOCC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3ccnc4c3ccn4C(F)F)ncc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c1c(Nc1ccc(N3CCC(O)CC3)cn1)cc(F)c2-c1ccnc2[nH]ccc12,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(C(F)F)ccn34)ccc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(CO)ccn34)ccc(Nc3ccc(N4CCOCC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3ccnc4[nH]ccc34)ncc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
N#Cc1ccn2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cnc2c1F,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccn2c(-c3ccc(Nc4ccc([C@H]5CCOC5)cn4)c4c3CNC4=O)cnc2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccn2c(-c3ccc(Nc4ccc([C@@H]5CCOC5)cn4)c4c3CNC4=O)cnc2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3c(Cl)cc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(Cl)ccn34)ccc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cnc2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cnn2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
N#Cc1ccn2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cnc2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cnn2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cnc2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1ccn2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cnc2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
N#Cc1ccn2c(-c3ccc(Nc4ccc(N5CCOCC5)cn4)c4c3CNC4=O)cnc2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3ccnc4[nH]ccc34)ncc(Nc3ccc(N4CCC[C@@H](O)C4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3ccc(N4CCC[C@@H](O)C4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4ccc(N5CCC[C@H](O)C5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3ccc(N4CCC[C@H](O)C4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(CO)ccn34)ccc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1cnc2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cccc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccn2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cnc2c1C,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccn2c(-c3ccc(Nc4ccc(N5CCC[C@H](O)C5)cn4)c4c3CNC4=O)cnc2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cnccn34)ccc(Nc3ccc(N4CCC[C@H](O)C4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(F)ccn34)ncc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccn2c(-c3ccc(Nc4ccc(N5CCC[C@@H](O)C5)cn4)c4c3CNC4=O)cnc2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cnccn34)ccc(Nc3ccc(N4CCC[C@@H](O)C4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4c(O)cccn34)ccc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccn2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cnc2c1=O,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4ccccn34)ncc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccn2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cnc2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3ccc(N4CCOCC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cccnn34)ccc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1nccn2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cnc12,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cccc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnn4cccnc34)ccc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1cnc2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccn2c(-c3ccc(Nc4ccc(C5CCOC5)cn4)c4c3CNC4=O)cnc2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccn2c(-c3ncc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cnc2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cnccn34)ccc(Nc3ccc(N4CCOCC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccn2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cnc2c1F,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4c(C(F)(F)F)cccn34)ccc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccn2c(-c3ccc(Nc4ccc(S(C)(=O)=O)cn4)c4c3CNC4=O)cnc2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)C(C)(C)c1ccc(Nc2ccc(-c3ccnc4c3ccn4C)c3c2C(=O)NC3)nc1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccn2c(-c3ccc(Nc4ccc(N5CCOCC5)cn4)c4c3CNC4=O)cnc2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)ncnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4n3CCOC4)ccc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc2ncc(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)n2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cnn2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3cnc(-c4c(-c5ccccc5)[nH]c5ccccc45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(C(F)(F)F)ccn34)ccc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cccc2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cnn12,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cccn2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cnc12,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4c(F)cccn34)ccc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc2ncc(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)n2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cnccn34)ccc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1nc(Nc2ccc(-c3ccnc4c3ccn4C)c3c2C(=O)NC3)cc1C1CCOCC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3cnc(-c4c(F)cnc5c4ccn5C)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnn4ccccc34)ccc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1cnc2c(-c3ccc(Nc4ccc(N5CCNCC5)cn4)c4c3CNC4=O)cccc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccn2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cnc2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4ccc(N5CCC[C@H](O)C5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4ccccn34)ccc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
N#Cc1ccn2c(-c3ccc(Nc4ccc(N5CCNCC5)cn4)c4c3CNC4=O)cnc2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccn2c(-c3ncc(Nc4ccc(N5CCNCC5)cn4)c4c3CNC4=O)cnc2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3ccnc4c3ccn4C(F)F)ccc(Nc3ccc(N4CCNCC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnn4cccnc34)ccc(Nc3ccc(N4CCNCC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4cnn5ccncc45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4cnn5cccnc45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4ccc(N5CCC[C@@H](O)C5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4cc(C5CCNCC5)n[nH]4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cnc2c(-c3ccc(Nc4ccc(N5CCN(C)CC5)cn4)c4c3CNC4=O)cnn2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4ccc(S(C)(=O)=O)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4ccc(N5CCOCC5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1ccc(Nc2ccc(-c3ccnc4c3ccn4C)c3c2C(=O)NC3)nc1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCOc2c(-c3ccc(Nc4ccc(N5CCNCC5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4ccccn34)ccc(Nc3ccc(N4CCCNCC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4ccc(C5CCOC5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3ccnc4ccsc34)ccc(Nc3ccc(N4CCNCC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cn(C)c2nccc(-c3ccc(Nc4ccc(N5CCNCC5)cn4)c4c3CNC4=O)c12,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4ccc(N5CCNCC5)cn4)c4c3CNC4=O)cccc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4ccccn34)ccc(Nc3ccc(N4CC5CCC(C4)N5)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN[C@@H]1CCCN(c2ccc(Nc3ccc(-c4ccnc5c4ccn5C)c4c3C(=O)NC4)nc2)C1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN[C@H]1CCCN(c2ccc(Nc3ccc(-c4ccnc5c4ccn5C)c4c3C(=O)NC4)nc2)C1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4ccc(C5CCNCC5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4ccc(N5CCC[C@H](N)C5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnn4ccccc34)ccc(Nc3ccc(N4CCNCC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4ccc(N5CCC[C@@H](N)C5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc2c(-c3ccc(Nc4ccc(N5CCNCC5)cn4)c4c3CNC4=O)cnn2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4ccc(N5CCNCC5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4cnc5n4CCNC5)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4c(F)cccn34)ccc(Nc3ccc(N4CCNCC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CNC1CCN(c2ccc(Nc3ccc(-c4cnc5cccnn45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4ncccn34)ccc(Nc3ccc(N4CCNCC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc2ncc(-c3ccc(Nc4ccc(N5CCNCC5)cn4)c4c3CNC4=O)n2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cccnn34)ccc(Nc3ccc(N4CCNCC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4nnc5ccccn45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4ccnc5cc[nH]c45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cccc2c(-c3ccc(Nc4ccc(N5CCNCC5)cn4)c4c3CNC4=O)cnn12,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4n3CCCC4)ccc(Nc3ccc(N4CCNCC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4ncnc5c4ccn5C)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4ccc(N5CCCNCC5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4cnc5c(C#N)cccn45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccn2c(-c3ncc(Nc4ccc(N5CCN(C)CC5)cn4)c4c3CNC4=O)cnc2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccn2c(-c3ccc(Nc4ccc(N5CCNCC5)cn4)c4c3CNC4=O)cnc2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4cnc5cnccn45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CNC1CCN(c2ccc(Nc3ccc(-c4cnc5cc(C)ccn45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4ccc(N5CC6CCC(C5)N6)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cccc2c(-c3ccc(Nc4ccc(N5CCN(C)CC5)cn4)c4c3CNC4=O)cnn12,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc2c(-c3ccc(Nc4ccc(N5CCN(C)CC5)cn4)c4c3CNC4=O)cnn2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4ccnc5c4CCN5)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccn2c(-c3ccc(Nc4ccc(N5CCN(C)CC5)cn4)c4c3CNC4=O)cnc2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4c(F)cnc5c4ccn5C)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4ccccn34)ncc(Nc3ccc(N4CCNCC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CNC1CCN(c2ccc(Nc3ccc(-c4cnc5ccccn45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CNC1CCN(c2ccc(Nc3ccc(-c4ccnc5c4ccn5C)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CNC1CCN(c2ccc(Nc3ccc(-c4ccnc5[nH]ccc45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4ccccn34)ccc(Nc3ccc(N4CCNCC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4cnc5cccnn45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3cnc(-c4cnc5ccccn45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cccn2c(-c3ccc(Nc4ccc(N5CCN(C)CC5)cn4)c4c3CNC4=O)cnc12,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc2ncc(-c3ccc(Nc4ccc(N5CCN(C)CC5)cn4)c4c3CNC4=O)n2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
COCCn1ccc2c(-c3ccc(Nc4ccc(N5CCN(C)CC5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4c[nH]c5ccccc45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4cnc5[nH]ccc5c4)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4cccc5[nH]ccc45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4c(-c5ccccc5)[nH]c5ccccc45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4cnc5ccccn45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(-c3ccc(Nc4ccc(N5CCN(C)CC5)cn4)c4c3CNC4=O)ccnc2[nH]1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1[nH]c2ccccc2c1-c1ccc(Nc2ccc(N3CCN(C)CC3)cn2)c2c1CNC2=O,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4ccnc5c4ccn5C)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2[nH]cc(-c3ccc(Nc4ccc(N5CCN(C)CC5)cn4)c4c3CNC4=O)c2cn1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4c[nH]c5cc(F)ccc45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4ccnc5[nH]ccc45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc2c(-c3ccc(Nc4ccc(N5CCN(C)CC5)cn4)c4c3CNC4=O)c[nH]c2n1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4c[nH]c5ccncc45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc2c(-c3ccc(Nc4ccc(N5CCN(C)CC5)cn4)c4c3CNC4=O)c[nH]c2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4c[nH]c5ncccc45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3cnc(-c4ccnc5[nH]ccc45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3cnc(-c4ccnc5c4ccn5C)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c[nH]c2nccc(-c3ncc(Nc4ccc(N5CCN(C)CC5)cn4)c4c3CNC4=O)c12,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3cnc(-c4c[nH]c5ncccc45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CCC(C)(O)C#Cc1cccc(COc2cc(-c3cnc(C4CCN(C)CC4)s3)cnc2N)c1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)Cc1cc(C#CC(C)(C)O)cc(COc2cc(-c3cnc(C4CCOCC4)s3)cnc2N)c1,HPK1,medium,100,ic50,WO2019206049A1_Original_document_20201120093115, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ncc(-c3cnc(N)c(OCc4cc(C#CC(C)(C)O)ccc4OC(F)F)c3)s2)CC1,HPK1,medium,100,ic50,WO2019206049A1_Original_document_20201120093115, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ncc(-c3cnc(N)c(OCc4cccc(C#CC(C)(C)O)c4)c3)s2)C1,HPK1,medium,100,ic50,WO2019206049A1_Original_document_20201120093115, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)c1ncc(-c2cnc(N)c(OCc3cc(C#CC(C)(C)O)cc(CN)c3)c2)s1,HPK1,medium,100,ic50,WO2019206049A1_Original_document_20201120093115, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2cnc(-c3cnc(N)c(OCc4cccc(C#CC(C)(C)O)c4)c3)s2)CC1,HPK1,medium,100,ic50,WO2019206049A1_Original_document_20201120093115, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ncc(-c3cnc(N)c(OCc4cccc(C#CC5(O)CCCC5=O)c4)c3)s2)CC1,HPK1,medium,100,ic50,WO2019206049A1_Original_document_20201120093115, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)C#Cc1ccc(CN)c(COc2cc(-c3cnc(C4CCOCC4)s3)cnc2N)c1,HPK1,medium,100,ic50,WO2019206049A1_Original_document_20201120093115, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ncc(-c3cnc(N)c(OCc4cc(C#CC(C)(C)O)cc(CN)c4)c3)s2)CC1,HPK1,medium,100,ic50,WO2019206049A1_Original_document_20201120093115, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)C#Cc1cc(CN)cc(COc2cc(-c3cnc(C4CCOCC4)s3)cnc2N)c1,HPK1,medium,100,ic50,WO2019206049A1_Original_document_20201120093115, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)C#Cc1cccc(COc2cc(-c3cnn(C4CCOCC4)c3)cnc2N)c1,HPK1,medium,100,ic50,WO2019206049A1_Original_document_20201120093115, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)C#Cc1cccc(COc2cc(-c3cnn(C4CCNCC4)c3)cnc2N)c1,HPK1,medium,100,ic50,WO2019206049A1_Original_document_20201120093115, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ncc(-c3cnc(N)c(OCc4cc(C#CC(C)(C)O)ccc4C(F)(F)F)c3)s2)CC1,HPK1,medium,100,ic50,WO2019206049A1_Original_document_20201120093115, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ncc(-c3cnc(N)c(OCc4ccc(F)c(C#CC(C)(C)O)c4)c3)s2)CC1,HPK1,medium,100,ic50,WO2019206049A1_Original_document_20201120093115, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(n2cc(-c3cnc(N)c(OCc4cc(C#CC(C)(C)O)ccc4F)c3)cn2)CC1,HPK1,medium,100,ic50,WO2019206049A1_Original_document_20201120093115, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(C2CCN(c3ncc(-c4cnc(N)c(OCc5cccc(C#CC(C)(C)O)c5)c4)s3)CC2)CC1,HPK1,medium,100,ic50,WO2019206049A1_Original_document_20201120093115, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1ncc(-c2cnc(N)c(OCc3cc(C#CC(C)(C)O)ccc3CN)c2)s1,HPK1,medium,100,ic50,WO2019206049A1_Original_document_20201120093115, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ncc(-c3cnc(N)c(OCc4cccc(C#CC(C)(O)CF)c4)c3)s2)CC1,HPK1,medium,100,ic50,WO2019206049A1_Original_document_20201120093115, not Ki or Kd; not used in NCI fingerprint analysis
CC1CC(O)(C#Cc2cccc(COc3cc(-c4cnc(C5CCN(C)CC5)s4)cnc3N)c2)C1,HPK1,medium,100,ic50,WO2019206049A1_Original_document_20201120093115, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1c[nH]c2ncc(-c3ccc(N)c(P(C)(C)=O)c3)cc12,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c[nH]c2ncc(-c3ccc(N)c(P(C)(C)=O)n3)cc12,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c[nH]c2ncc(-c3ccc(N)c(P(C)(C)=O)c3)cc12,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c(Cl)[nH]c2ncc(-c3ccc(N)c(P(C)(C)=O)c3)cc12,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c[nH]c2ncc(-c3ccc(C)c(P(C)(C)=O)n3)cc12,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c[nH]c2ncc(-c3ccc(C)c(P(C)(C)=O)c3F)cc12,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c[nH]c2ncc(-c3ccc(F)c(P(C)(C)=O)c3N)cc12,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c[nH]c2ncc(-c3ccc(NC(C)=O)c(P(C)(C)=O)c3)cc12,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c[nH]c2ncc(-c3cc(N)cc(P(C)(C)=O)c3)cc12,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c[nH]c2ncc(-c3ccc(O)c(P(C)(C)=O)c3)cc12,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c[nH]c2ncc(-c3ccc(Cl)c(P(C)(C)=O)c3)cc12,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c[nH]c2ncc(-c3ccc(F)c(P(C)(C)=O)c3)cc12,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c[nH]c2ncc(-c3ccc(C)c(P(C)(C)=O)c3)cc12,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc3ccc(=O)n(-c4ccccc4)c3n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc3cc(C(=O)O)n(-c4ccccc4)c3n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc3cc(C#N)n(-c4ccccc4)c3n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc3ccn(-c4cccnc4C)c3n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc3ccn(-c4cccnc4)c3n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc3ccn(-c4ccccn4)c3n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc3ccn(-c4ccccc4)c3n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(C(=O)O)C4(CCCC4)C3)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(C(=O)O)C4(CCOCC4)C3)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(C(=O)O)C4(CCCCC4)C3)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-c3nn(CC(=O)O)c4ccccc34)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-c3cn(CC(=O)O)c4ccccc34)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(C)(CC(=O)O)c4ccccc43)n1)CN(C)C2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(C)(CC(=O)O)c4ccccc43)n1)CN(C(C)C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCc2cc(OC)c(Nc3ncc(Cl)c(N4CC(C)(CC(=O)O)c5ccccc54)n3)cc2C1,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCc2cc(F)c(Nc3ncc(Cl)c(N4CC(C)(CC(=O)O)c5ccccc54)n3)cc2C1,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1nc2c(cc1Nc1ncc(Cl)c(N3CC(C)(CC(=O)O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(C)(CC(=O)O)c4cc(F)c(F)cc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3C[C@@](C)(CC(=O)O)c4ccc(F)cc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3C[C@](C)(CC(=O)O)c4ccc(F)cc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(C)(CC(=O)O)c4ccc(F)cc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(C)(CC(=O)O)c4cc(F)ccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)CC1(C)CN(c2nc(Nc3cc4c(cc3OC)CCN(C)C4)ncc2Cl)c2ccccc21,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3C[C@@](C)(CC(=O)O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3C[C@](C)(CC(=O)O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(C)(CC(=O)O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)CC1(C)CN(c2nc(Nc3cc4c(cc3OC)CCN(C)C4)ncc2Cl)c2ccccc21,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-n3cc(C(C(=O)O)C(F)(F)F)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-n3cc(C4(C(=O)O)CC4)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-n3cc(C(C)C(=O)O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-n3nc(CC(=O)O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-n3cc(CC(=O)O)c4cc(F)c(F)cc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-n3cc(CC(=O)O)c4ccc(F)cc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-n3cc(CC(=O)O)c4cc(F)ccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-n3cc(CC(=O)NCC#N)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)Cc1cn(-c2nc(Nc3cc4c(cc3OC)CCN(C)C4)ncc2Cl)c2ccccc12,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-n3cc(Cc4nn[nH]n4)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-n3cc(CC#N)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-n3cc(CC(N)=O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)Cc1cn(-c2nc(Nc3cc4c(cc3OC)CCN(C)C4)ncc2Cl)c2ccccc12,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-n3cc(CC(=O)OC(C)C)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-n3cc(CC(=O)O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(CC(=O)O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(C)(C(=O)O)c4ccccc43)n1)CNCC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(C)(C(=O)O)c4ccc(F)cc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(C)(C(=O)O)c4cc(F)ccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(CO)(C(=O)O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(C)(CO)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)C1(C)CN(c2nc(Nc3cc4c(cc3OC)CCN(C)C4)ncc2Cl)c2ccccc21,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(C)(C#N)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(C)(C(N)=O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3C[C@](C)(C(=O)O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3C[C@@](C)(C(=O)O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(C)(C(=O)O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)C1(C)CN(c2nc(Nc3cc4c(cc3OC)CCN(C)C4)ncc2Cl)c2ccccc21,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-n3cc(C(=O)O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)c1cn(-c2nc(Nc3cc4c(cc3OC)CCN(C)C4)ncc2Cl)c2ccccc12,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-n3cc(C(N)=O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-n3nc(C(=O)O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)C1CN(c2nc(Nc3cc4c(cc3OC)CCN(C)C4)ncc2C(F)F)c2ccccc21,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)Oc1cc2c(cc1Nc1ncc(Cl)c(N3CC(C(=O)O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C#N)c(N3CC(C(=O)O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(F)c(N3CC(C(=O)O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(C(=O)O)c4c(OC)cccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc2c(c1)N(c1nc(Nc3cc4c(cc3OC)CCN(C)C4)ncc1Cl)CC2C(=O)O,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc2c(c1)C(C(=O)O)CN2c1nc(Nc2cc3c(cc2OC)CCN(C)C3)ncc1Cl,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(C(=O)O)c4ccc(F)cc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(C(=O)O)c4cc(F)ccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1nccc(N3CC(C(=O)O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CONC(=O)C1CN(c2nc(Nc3cc4c(cc3OC)CCN(C)C4)ncc2Cl)c2ccccc21,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(C(=O)N(C)O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(C(=O)NO)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(c4nn[nH]n4)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(C#N)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(C(=O)NS(C)(=O)=O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)C1CN(c2nc(Nc3cc4c(cc3OC)CCN(C)C4)ncc2Cl)c2ccccc21,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(C(N)=O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3C[C@@H](C(=O)O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3C[C@H](C(=O)O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)C1CN(c2nc(Nc3cc4c(cc3OC)CCN(C)C4)ncc2Cl)c2ccccc21,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(C(=O)O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-n3cc(NS(C)(=O)=O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-c3cncc4ccccc34)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CCc4c(C(F)F)cccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CCc4ccc(C(F)F)cc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CCc4cc(C(F)F)ccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CCc4c(OC)cccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(P(C)(C)=O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(CO)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CCc4cc(P(C)(C)=O)ccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CCc4cc(Br)ccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC4(CC4)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(C)(C)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-n3ncc4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CCc4ccc(F)cc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CCc4cc(F)ccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1nc2c(cc1Nc1ncc(Cl)c(N3CCc4ncccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CCc4ncccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CCc4ccc(Cl)cc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CCc4cc(Cl)ccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CCc4ccccc43)n1)CN(CCO)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CCc4ccccc43)n1)CN(C(=O)CN(C)C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CCc4ccccc43)n1)CNCC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CCc4ccccc43)n1)CN(C(C)C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1nc2c(cc1Nc1ncc(Cl)c(N3CCc4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCc2cc(Cl)c(Nc3ncc(Cl)c(N4CCc5ccccc54)n3)cc2C1,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCc2ccc(Nc3ncc(Cl)c(N4CCc5ccccc54)n3)cc2C1,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-n3cc(S(N)(=O)=O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-n3cc(CS(C)(=O)=O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CC(S(C)(=O)=O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-n3cc(S(C)(=O)=O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-n3cc(F)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C(F)(F)F)c(-n3ccc4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-n3cnc4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-n3cc(C(=O)N(C)C)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CCOc4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CCCc4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CCc4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C(F)(F)F)c(N3CCc4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-n3ccc4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-n3cc(P(C)(C)=O)c4ccccc43)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H](N)c1nc(N2CCC[C@H]2C)cc2c1CN(c1cccc(-c3nnc4n3[C@@H](CF)CC4)n1)C2=O,HPK1,active,0.05,Ki,WO2021220185A1（HPK1）,Below 1 nM
CC[C@@H](N)c1nc(N2CCC[C@H]2C)cc2c1CN(c1cccc(-c3nnc4n3[C@@H](CO)CC4)n1)C2=O,HPK1,active,0.05,Ki,WO2021220185A1（HPK1）,Below 1 nM
C[C@@H](N)c1nc(N2CCC[C@H]2C)cc2c1CN(c1cccc(-c3nnc4n3[C@H](C)CC4)n1)C2=O,HPK1,active,0.05,Ki,WO2021220185A1（HPK1）,Below 1 nM
CNCc1nc(N(C)C(C)C)cc2c1CN(c1cccc(-c3nnc4n3[C@@H](C)C[C@@H]4C)n1)C2=O,HPK1,active,0.05,Ki,WO2021220185A1（HPK1）,Below 1 nM
CNCc1nc(N(C)C(C)C)cc2c1CN(c1cccc(-c3nnc4n3[C@@H](C)CC4)n1)C2=O,HPK1,active,0.05,Ki,WO2021220185A1（HPK1）,Below 1 nM
CNCc1nc(N(C)C(C)C)cc2c1CN(c1cccc(-c3nnc4n3[C@@H](CF)CC4)n1)C2=O,HPK1,active,0.05,Ki,WO2021220185A1（HPK1）,Below 1 nM
CNCc1nc(N2CCC[C@H]2C)cc2c1CN(c1cccc(-c3nnc4n3[C@@H](CF)CC4)n1)C2=O,HPK1,active,0.06,Ki,WO2021220185A1（HPK1）,Below 1 nM
CC[C@H]1CCc2nnc(-c3cccc(N4Cc5c(cc(N(C)C(C)C)nc5CNC)C4=O)n3)n21,HPK1,active,0.05,Ki,WO2021220185A1（HPK1）,Below 1 nM
CC[C@H]1CCc2nnc(-c3cccc(N4Cc5c(cc(N6CCC[C@H]6C)nc5CNC)C4=O)n3)n21,HPK1,active,0.05,Ki,WO2021220185A1（HPK1）,Below 1 nM
CC[C@@H](N)c1nc(N2CCC[C@H]2C)cc2c1CN(c1cccc(-c3nncn3CC)n1)C2=O,HPK1,active,0.07,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCn1cnnc1-c1cccc(N2Cc3c(cc(N4CCC[C@H]4C)nc3[C@@H](C)NC)C2=O)n1,HPK1,active,0.09,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCn1cnnc1-c1cccc(N2Cc3c(cc(N4CCC[C@H]4C)nc3C(C)(C)N)C2=O)n1,HPK1,active,0.05,Ki,WO2021220185A1（HPK1）,Below 1 nM
CC[C@@H](N)c1nc(C2(C)CC2)cc2c1CN(c1cccc(-c3nnc4n3[C@@H](C)CC4)n1)C2=O,HPK1,active,0.05,Ki,WO2021220185A1（HPK1）,Below 1 nM
CC[C@@H](N)c1nc(C2(C)CC2)cc2c1CN(c1cccc(-c3nnc4n3[C@@H](CO)CC4)n1)C2=O,HPK1,active,0.074,Ki,WO2021220185A1（HPK1）,Below 1 nM
CC[C@@H](N)c1nc(N2CCC[C@H]2C)cc2c1CN(c1cccc(-c3nnc4n3[C@@H](CF)CC4)n1)C2=O,HPK1,active,0.06,Ki,WO2021220185A1（HPK1）,Below 1 nM
C[C@@H](N)c1nc(N2CCC[C@H]2C)cc2c1CN(c1cccc(-c3nnc4n3[C@@H](CO)CC4)n1)C2=O,HPK1,active,0.05,Ki,WO2021220185A1（HPK1）,Below 1 nM
CC[C@@H](N)c1nc(N(C)C)cc2c1CN(c1cccc(-c3nnc4n3[C@@H](C)CC4)n1)C2=O,HPK1,active,0.045,Ki,WO2021220185A1（HPK1）,Below 1 nM
C[C@H](N)c1nc(N2CCC[C@H]2C)cc2c1CN(c1cccc(-c3nnc4n3[C@H](C)CC4)n1)C2=O,HPK1,active,0.05,Ki,WO2021220185A1（HPK1）,Below 1 nM
C[C@H]1CCc2nnc(-c3cccc(N4Cc5c(cc(N(C)C)nc5C(C)(C)N)C4=O)n3)n21,HPK1,active,0.08,Ki,WO2021220185A1（HPK1）,Below 1 nM
CC(C)N(C)c1cc2c(c([C@@H](C)N)n1)CN(c1cccc(-c3nnc4n3[C@@H](C)CC4)n1)C2=O,HPK1,active,0.064,Ki,WO2021220185A1（HPK1）,Below 1 nM
CC[C@@H](N)c1nc(N(C)C(C)C)cc2c1CN(c1cccc(-c3nnc4n3[C@@H](CO)CC4)n1)C2=O,HPK1,active,0.05,Ki,WO2021220185A1（HPK1）,Below 1 nM
C[C@@H]1CCCN1c1cc2c(c(C(C)(C)N)n1)CN(c1cccc(-c3nnc4n3[C@@H](N)CC4)n1)C2=O,HPK1,active,0.05,Ki,WO2021220185A1（HPK1）,Below 1 nM
CC[C@H](N)c1nc(N2CCC[C@H]2C)cc2c1CN(c1cccc(-c3nnc4n3[C@H](CC)CC4)n1)C2=O,HPK1,active,0.093,Ki,WO2021220185A1（HPK1）,Below 1 nM
CC[C@@H](N)c1nc(N2CCC[C@H]2C)cc2c1CN(c1cccc(-c3nnc4n3[C@H](CC)CC4)n1)C2=O,HPK1,active,0.07,Ki,WO2021220185A1（HPK1）,Below 1 nM
CC[C@@H](N)c1nc(N(C)C(C)C)cc2c1CN(c1cccc(-c3nnc4n3[C@@H](C)CC4)n1)C2=O,HPK1,active,0.05,Ki,WO2021220185A1（HPK1）,Below 1 nM
CC[C@H]1CCc2nnc(-c3cccc(N4Cc5c(cc(N(C)C(C)C)nc5[C@@H](C)N)C4=O)n3)n21,HPK1,active,0.05,Ki,WO2021220185A1（HPK1）,Below 1 nM
CC[C@H]1CCc2nnc(-c3cccc(N4Cc5c(cc(N6CCC[C@H]6C)nc5[C@H](C)N)C4=O)n3)n21,HPK1,active,0.05,Ki,WO2021220185A1（HPK1）,Below 1 nM
CC[C@H]1CCc2nnc(-c3cccc(N4Cc5c(cc(N6CCC[C@H]6C)nc5[C@@H](C)N)C4=O)n3)n21,HPK1,active,0.05,Ki,WO2021220185A1（HPK1）,Below 1 nM
CC[C@@H](N)c1nc(N2CCC[C@H]2C)cc2c1CN(c1cccc(-c3nnc4n3[C@@H](C)CC4)n1)C2=O,HPK1,active,0.05,Ki,WO2021220185A1（HPK1）,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC4)ncc2c(N)c1F,HPK1,active,0.013,Ki,WO2018183964A1(1),Below 1 nM
Cc1cnsc1-c1cc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3C#N)cc2c1,HPK1,active,0.082,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3C#N)cc2c1,HPK1,active,0.0816,Ki,WO2018183964A1(1),Below 1 nM
C[C@H]1COC(=O)N1c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3C#N)cc2c1,HPK1,active,0.052,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC43CC3)ncc2c(N)c1F,HPK1,active,0.015,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3CC#N)ncc2c(N)c1Cl,HPK1,active,0.0405,Ki,US2018282282A1（HPK1）,Below 1 nM
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)[C@@H]3[C@@H](C)[C@H]3c3cnn(C)c3)cc2c1,HPK1,active,0.0564,Ki,WO2018183964A1(1),Below 1 nM
CC[C@H](C)C1C=NN=C1c1cccc(N2Cc3c(cc(N(C)CC)nc3CNC)C2=O)n1,HPK1,active,0.06,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CCC(CC)n1cnnc1-c1cccc(N2Cc3c(cc(N(C)C(C)C)nc3CN)C2=O)n1,HPK1,active,0.06,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCC(CC)n1cnnc1-c1cccc(N2Cc3c(cc(N4CCC[C@H]4C)nc3CNC)C2=O)n1,HPK1,active,0.09,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N4CCC[C@H]4C)nc3CNC)C2=O)n1,HPK1,active,0.09,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CNCc1nc(N2CCCC2(C)C)cc2c1CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,0.06,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CC(C)n1cnnc1-c1cccc(N2Cc3c(cc(N4CCC[C@H]4C)nc3CN)C2=O)n1,HPK1,active,0.04,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CC(C)N(C)c1cc2c(c(CN)n1)CN(c1cccc(N3C(=O)OC[C@@H]3C)n1)C2=O,HPK1,active,0.05,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CCn1cnnc1-c1cccc(N2Cc3c(cc(N(C)C(C)C)nc3CN)C2=O)n1,HPK1,active,0.08,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CC(C)N(C)c1cc2c(c(CN)n1)CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,0.05,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(N(C)C(C)C)cc2c1CN(c1cccc(N3C(=O)OC[C@@H]3C)n1)C2=O,HPK1,active,0.06,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
C[C@@H]1CCCN1c1cc2c(c(CN)n1)CN(c1cccc(N3C(=O)OC[C@@H]3CF)n1)C2=O,HPK1,active,0.07,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(N(C)C(C)C)nc3CNC)C2=O)n1,HPK1,active,0.09,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N4CCC[C@H]4C)nc3CNC)C2=O)n1,HPK1,active,0.09,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(N4CCC[C@H]4C)nc3CNC)C2=O)n1,HPK1,active,0.06,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CC[C@@H](CC(F)(F)F)C1C=NN=C1c1cccc(N2Cc3c(cc(N(C)C)nc3CNC)C2=O)n1,HPK1,active,0.05,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CNCc1nc(N(C)C)cc2c1CN(c1cccc(-c3nncn3[C@@H](C)CC(F)(F)F)n1)C2=O,HPK1,active,0.05,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CNCc1nc(N2CCCC2)cc2c1CN(c1cccc(-c3nncn3[C@@H](C)CC(F)(F)F)n1)C2=O,HPK1,active,0.07,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
C[C@@H](CC(F)(F)F)n1cnnc1-c1cccc(N2Cc3c(cc(N(C)C)nc3CN)C2=O)n1,HPK1,active,0.08,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CC(C)c1[nH]ncc1-c1cccc(N2Cc3c(cc(N(C)C)nc3CN)C2=O)n1,HPK1,active,0.09,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C#N)ncc2c(N)c1Cl,HPK1,active,0.0405,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)Cc4nccn4CC5)ncc3cc2F)cnc2c1NCC[C@H]2O,HPK1,active,0.02,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N([C@H](C)C#N)CC4)ncc2cc1F,HPK1,active,0.032,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N([C@@H](C)C#N)CC4)ncc2cc1F,HPK1,active,0.014,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N([C@@H](C)CO)CC4)ncc2cc1F,HPK1,active,0.019,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N([C@H](C)CO)CC5)ncc3cc2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N([C@@H](C)CO)CC5)ncc3cc2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N([C@H](C)C#N)CC5)ncc3cc2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N([C@@H](C)C#N)CC5)ncc3cc2F)cnc2c1NCCO2,HPK1,active,0.014,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)Cc4nccn4CC5)ncc3cc2F)cnc2c1NCC[C@@H]2O,HPK1,active,0.013,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC5)ncc3cc2F)cnc2c1NCC[C@@H]2O,HPK1,active,0.062,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC5)ncc3cc2F)cnc2c1NCCC2O,HPK1,active,0.076,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC54CC4)ncc3cc2F)cnc2c1NCC[C@@]2(C)O,HPK1,active,0.016,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC54CC4)ncc3cc2F)cnc2c1NCC[C@]2(C)O,HPK1,active,0.09,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC54CC4)ncc3cc2F)cnc2c1NCCC2O,HPK1,active,0.013,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC54CC4)ncc3cc2F)cnc2c1NCC[C@H]2O,HPK1,active,0.013,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)OC5)ncc3cc2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020023560A1,Below 1 nM
Cc1cc2cnc(Nc3cc4n(n3)CC(=O)N(C)CC4)cc2cc1-c1cnc2c(c1C)NCC(C)(C)C2=O,HPK1,active,0.014,Ki,WO2020023560A1,Below 1 nM
Cc1cc2cnc(Nc3cc4n(n3)CC(=O)NCC4)cc2cc1-c1cncc(NCC(F)(F)F)c1C,HPK1,active,0.062,Ki,WO2020023560A1,Below 1 nM
Cc1c(CC#N)cncc1-c1cc(F)c2cnc(Nc3cc4n(n3)CC(=O)NCC4)cc2c1,HPK1,active,0.076,Ki,WO2020023560A1,Below 1 nM
CN1CCc2cc(Nc3cc4cc(-c5cncc(N)c5C(F)(F)F)c(F)cc4cn3)nn2CC1=O,HPK1,active,0.029,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1cc(F)c2cnc(Nc3cc4n(n3)CC(=O)NCC43CC3)cc2c1,HPK1,active,0.013,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)NCC43CC3)ncc2cc1F,HPK1,active,0.013,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2c(F)cc3cnc(Nc4cc5n(n4)CC(=O)N(C)CC5)cc3c2F)cnc2c1NCCO2,HPK1,active,0.04,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC5)ncc3cc2F)cnc2c1NCCC2(F)F,HPK1,active,0.02,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)NCC5)ncc3cc2F)cnc2c1NCCC2,HPK1,active,0.018,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)NCC5)ncc3cc2F)cnc2c1NCC(C)O2,HPK1,active,0.018,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)Cc4nccn4CC5)ncc3cc2F)cnc2c1NCCCO2,HPK1,active,0.013,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)NCC5)ncc3cc2F)cnc2c1NC(C)CO2,HPK1,active,0.073,Ki,WO2020023560A1,Below 1 nM
CNc1cncc(-c2cc3cc(Nc4cc5n(n4)CC(=O)NCC5)ncc3cc2F)c1C,HPK1,active,0.026,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2ccc3cnc(Nc4cc5n(n4)CC(=O)N(C)CC5)cc3c2F)cnc2c1NCCO2,HPK1,active,0.026,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)Cc3nccn3CC4O)ncc2c(F)c1F,HPK1,active,0.035,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1cc(F)c2cnc(Nc3cc4n(n3)Cc3nccn3CC4)cc2c1,HPK1,active,0.028,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(CCN3CC(O)C3)CC4)ncc2cc1F,HPK1,active,0.013,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(CCN3CC(F)C3)CC4)ncc2cc1F,HPK1,active,0.013,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)Cc3ncc(C)n3CC4)ncc2cc1F,HPK1,active,0.013,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)Cc4nccn4CC5)ncc3c(F)c2F)cnc2c1NCCO2,HPK1,active,0.014,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)NCC5)ncc3cc2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(CCO)CC4)ncc2cc1F,HPK1,active,0.015,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(CC(C)(C)O)CC4)ncc2cc1F,HPK1,active,0.023,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)Cc3nccn3CC4)ncc2c(F)c1F,HPK1,active,0.014,Ki,WO2020023560A1,Below 1 nM
COCCN1CCc2cc(Nc3cc4cc(-c5cncc(N)c5C)c(F)cc4cn3)nn2CC1=O,HPK1,active,0.017,Ki,WO2020023560A1,Below 1 nM
COCCN1CCc2cc(Nc3cc4cc(-c5cnc6c(c5C)NCCO6)c(F)cc4cn3)nn2CC1=O,HPK1,active,0.013,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1ccc2cnc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)cc2c1Cl,HPK1,active,0.028,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)Cc4nncn4CC5)ncc3cc2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2ccc3cnc(Nc4cc5n(n4)CC(=O)N(CCO)CC5)cc3c2F)cnc2c1NCCO2,HPK1,active,0.034,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(CCO)CC5)ncc3cc2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)NCC4)ncc2cc1F,HPK1,active,0.062,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)Cc4nccn4CC5)ncc3cc2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)ncc2cc1Cl,HPK1,active,0.086,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)Cc3nncn3CC4)ncc2cc1F,HPK1,active,0.076,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC5)ncc3c(F)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(CCN3CCOCC3)CC4)ncc2cc1F,HPK1,active,0.028,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C(C)C)CC5)ncc3c(F)c2F)cnc2c1NCCO2,HPK1,active,0.038,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(CCN4CCOCC4)CC5)ncc3cc2F)cnc2c1NCCO2,HPK1,active,0.02,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)ncc2c(C)c1C#N,HPK1,active,0.068,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1ccc2cnc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)cc2c1,HPK1,active,0.04,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC5)ncc3cc2F)cnc2c1NCCO2,HPK1,active,0.01,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC4(F)F)ncc2cc1F,HPK1,active,0.04,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)Cc3nccn3CC4)ncc2cc1F,HPK1,active,0.03,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)ncc2c(C)c1F,HPK1,active,0.08,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)C(C)(C)C4)ncc2cc1F,HPK1,active,0.04,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)ncc2cc1F,HPK1,active,0.05,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)ncc2c(F)c1F,HPK1,active,0.065,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C(C)C)CC5)ncc3cc2F)cnc2c1NCCO2,HPK1,active,0.014,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC43CC3)ncc2cc1F,HPK1,active,0.01,Ki,WO2020023560A1,Below 1 nM
CC[C@@H](C)C1C=NN=C1c1cccc(N2Cc3c(cc(N(C)CC)nc3CNC)C2=O)n1,HPK1,active,0.06,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N4CCC[C@@H]4C)nc3CNC)C2=O)n1,HPK1,active,0.09,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CC(C)n1cnnc1-c1cccc(N2Cc3c(cc(N4CCC[C@@H]4C)nc3CN)C2=O)n1,HPK1,active,0.04,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CC(C)N(C)c1cc2c(c(CN)n1)CN(c1cccc(N3C(=O)OC[C@H]3C)n1)C2=O,HPK1,active,0.05,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(N(C)C(C)C)cc2c1CN(c1cccc(N3C(=O)OC[C@H]3C)n1)C2=O,HPK1,active,0.06,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
C[C@H]1CCCN1c1cc2c(c(CN)n1)CN(c1cccc(N3C(=O)OC[C@H]3CF)n1)C2=O,HPK1,active,0.07,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N4CCC[C@@H]4C)nc3CNC)C2=O)n1,HPK1,active,0.09,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(N4CCC[C@@H]4C)nc3CNC)C2=O)n1,HPK1,active,0.06,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(N(C)C)cc2c1CN(c1cccc(-c3nncn3[C@H](C)CC(F)(F)F)n1)C2=O,HPK1,active,0.05,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(N2CCCC2)cc2c1CN(c1cccc(-c3nncn3[C@H](C)CC(F)(F)F)n1)C2=O,HPK1,active,0.07,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
C[C@H](CC(F)(F)F)n1cnnc1-c1cccc(N2Cc3c(cc(N(C)C)nc3CN)C2=O)n1,HPK1,active,0.08,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N[C@H]4C[C@@H](F)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N[C@@H]4CCOC[C@@H]4F)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N[C@H]4CCOC[C@H]4F)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)NC4CC5(CCOC5)C4)ncc3c(N)c2F)cnc2c1NCCC2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N[C@H]4C[C@H]4F)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
CO[C@H]1C[C@H](NC(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)c(N)c3cn2)C1,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N[C@H]4CC[C@@H](C#N)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.016,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N[C@@H]4CC[C@H](C#N)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N[C@@H]4CCCOC4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N[C@H]4CCCOC4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N[C@H]4CCN(C)C[C@H]4F)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.03,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N[C@H]4CCN(C)C[C@@H]4F)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N[C@@H]4CCN(C)C[C@H]4F)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.022,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CCN([C@@H]5CCOC5)C[C@H]4F)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.031,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CCN([C@H]5CCOC5)C[C@H]4F)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.029,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CC[C@@H]4C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CC[C@H]4C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CC[C@@H]4C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.025,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc(N)c3cnc(NC(=O)O[C@H]4C[C@@H](C#N)C4)cc3c2)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc(N)c3cnc(NC(=O)O[C@@H]4COC[C@H]4C)cc3c2)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc(N)c3cnc(NC(=O)O[C@H]4COC[C@@H]4C)cc3c2)cnc2c1NCCO2,HPK1,active,0.032,Ki,WO2020072695A1,Below 1 nM
CCc1c(-c2cc3cc(NC(=O)O[C@H]4COC[C@@H]4C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@H](N5CCOCC5)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@H](C(C)(C)C#N)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@@H](C(C)(C)C#N)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
CO[C@@H]1COC[C@H]1OC(=O)Nc1cc2cc(-c3cnc4c(c3C)NCCO4)c(F)c(N)c2cn1,HPK1,active,0.051,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CN(C(=O)[C@@H]5C[C@H]5F)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.018,Ki,WO2020072695A1,Below 1 nM
CC(=O)O[C@]1(C)C[C@H](OC(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)c(N)c3cn2)C1,HPK1,active,0.019,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4[C@@H]5CN(S(C)(=O)=O)C[C@@H]54)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
CNC(=O)[C@H]1C[C@@H](OC(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)c(N)c3cn2)C1,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@@H](C(=O)N(C)C)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CCOC4)ncc3c(N)c2F)cnc2c1NC[C@H](F)O2,HPK1,active,0.044,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CCOC4)ncc3c(N)c2F)cnc2c1NC[C@@H](F)O2,HPK1,active,0.069,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@@H](C(=O)N5CCC5)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4COC[C@@H]4C4CC4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4COC[C@H]4C4CC4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.031,Ki,WO2020072695A1,Below 1 nM
CC[C@H]1COC[C@@H]1OC(=O)Nc1cc2cc(-c3cnc4c(c3C)NCCO4)c(F)c(N)c2cn1,HPK1,active,0.017,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@H](n5ccnc5)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@@H](N5CC(F)(F)C5)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.022,Ki,WO2020072695A1,Below 1 nM
CC[C@]1(O)C[C@@H](OC(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)c(N)c3cn2)C1,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
CC[C@]1(O)C[C@H](OC(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)c(N)c3cn2)C1,HPK1,active,0.015,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CCO[C@@H]4C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.016,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4[C@@H]5CN(C6COC6)C[C@@H]54)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4[C@@H]5CN(C(C)C)C[C@@H]54)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@](C)(O)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.018,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CC(=O)N(C)C4)ncc3c(N)c2F)cnc2c1NCCC2,HPK1,active,0.018,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CCN(C5COC5)C[C@H]4F)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CCN(C5COC5)C[C@@H]4F)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.015,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CCN(C)CC4F)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CCOC4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.023,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4C[C@@](C)(O)[C@H]4C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.018,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@](C)(O)[C@@H]4C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.015,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@@](C)(O)[C@H]4C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.016,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4[C@@H]5COC[C@@H]54)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.083,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CC[C@@H]4O)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.078,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4COC[C@@H]4C#N)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.016,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@](C)(C#N)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@H](CC#N)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CC[C@H]4C#N)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.029,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CC[C@H]4O)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.014,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CC[C@](C)(O)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.015,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CC[C@@](C)(O)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.014,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CC[C@@](C)(O)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.059,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@@H](CO)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CN(C)C[C@@H]4F)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N[C@@H]4COC[C@@H]4F)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.019,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4COC[C@@H]4F)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.017,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CO[C@@H]5COC[C@@H]54)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.025,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@@H](C(C)(C)O)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@@H]([C@H](C)O)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@H]([C@@H](C)O)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.017,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@H]([C@H](C)O)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.019,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CN(C)C[C@H]4F)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.036,Ki,WO2020072695A1,Below 1 nM
CO[C@@H]1COCC[C@@H]1OC(=O)Nc1cc2cc(-c3cnc4c(c3C)NCCO4)c(F)c(N)c2cn1,HPK1,active,0.099,Ki,WO2020072695A1,Below 1 nM
CO[C@H]1COCC[C@H]1OC(=O)Nc1cc2cc(-c3cnc4c(c3C)NCCO4)c(F)c(N)c2cn1,HPK1,active,0.021,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N[C@H]4C[C@H](F)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.018,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CC[C@H](O)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.02,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@H](C(F)F)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
CO[C@@H]1CC[C@H](NC(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)c(N)c3cn2)C1,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
CO[C@H]1CC[C@H](NC(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)c(N)c3cn2)C1,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
CO[C@H]1CC[C@@H](NC(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)c(N)c3cn2)C1,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N[C@H]4CCC[C@H]4F)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
CO[C@H]1CCC[C@H]1NC(=O)Nc1cc2cc(-c3cnc4c(c3C)NCCO4)c(F)c(N)c2cn1,HPK1,active,0.015,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC[C@]4(F)CCN(C)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
CO[C@H]1COC[C@H]1NC(=O)Nc1cc2cc(-c3cnc4c(c3C)NCCO4)c(F)c(N)c2cn1,HPK1,active,0.029,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CC(=O)N(C(C)C)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N[C@@H]4C[C@@H]4C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CCC[C@@H]4C#N)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CO[C@@]5(CCN(C)C5)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CO[C@]5(CCN(C)C5)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.027,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CO[C@]5(CCN(C)C5)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.064,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N[C@@H]4CCOC4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CO[C@H]5OCC[C@@H]45)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.018,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@H](O)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CCC5(CCN(C6COC6)CC5)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
CCN1C[C@@H](OC(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)c(N)c3cn2)CC1=O,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
CCc1c(-c2cc3cc(NC(=O)O[C@H]4CC(=O)N(C)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CN(C)C[C@@H]4C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.046,Ki,WO2020072695A1,Below 1 nM
CO[C@H]1COCC[C@H]1NC(=O)Nc1cc2cc(-c3cnc4c(c3C)NCCO4)c(F)c(N)c2cn1,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4COCCN(C)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.084,Ki,WO2020072695A1,Below 1 nM
CC(=O)N1CC[C@@H](OC(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)c(N)c3cn2)[C@@H](F)C1,HPK1,active,0.054,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CCCN(C)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.075,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CCCNC4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.069,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CCOC4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.064,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4C[C@](C)(O)[C@@H]4C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.015,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N4CCC4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.02,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N4CC5(CCOCC5)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.039,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)NC(C)C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)NC4CC5(C4)CN(CC(F)F)C5)ncc3c(N)c2F)cnc2c1NCCC2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N[C@H]4C[C@H]4C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N[C@H]4C[C@H](F)C4)ncc3c(N)c2F)cnc2c1NCCC2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
CO[C@@H]1CC[C@@H](NC(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)c(N)c3cn2)C1,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N[C@H]4CCC[C@H]4O)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N[C@@H]4CCC[C@@H]4F)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)NC4CC(=O)N(C)C4)ncc3c(N)c2F)cnc2c1NCCC2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N[C@H]4COC[C@H]4F)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.019,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N[C@H]4CCOC4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)NC4CN(CC(F)(F)F)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
CCNC(=O)Nc1cc2cc(-c3cnc4c(c3C)NCCO4)c(F)c(N)c2cn1,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N[C@H]4CCOC4)ncc3c(N)c2F)cnc2c1NCCC2,HPK1,active,0.016,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)NC4CC(F)(F)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)NC4CCC4C#N)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
CC(=O)N1CC[C@H](NC(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)c(N)c3cn2)[C@H](F)C1,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
CC(=O)N1CC2(CC(NC(=O)Nc3cc4cc(-c5cnc6c(c5C)NCCO6)c(F)c(N)c4cn3)C2)C1,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)NC4CC5(C4)CN(CC(F)(F)F)C5)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)NC4CCC4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)NC4CCCC4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
CNC(=O)Nc1cc2cc(-c3cnc4c(c3C)NCCO4)c(F)c(N)c2cn1,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)NC4CC4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)NC4CCOCC4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)SC4CCOCC4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CC[C@@H](O)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.02,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CC5(CCNCC5)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4Cc5ncnn5C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.028,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@@H](C(F)F)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.015,Ki,WO2020072695A1,Below 1 nM
CO[C@H]1C[C@H](OC(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)c(N)c3cn2)C1,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@@H]([C@@H](C)O)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.015,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@@H](S(C)(=O)=O)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@H](CO)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.014,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CCOC4)ncc3c(N)c2F)cnc2c1C(C#N)CCO2,HPK1,active,0.068,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@@H](O)C4)ncc3c(N)c2F)cnc2c1NC[C@@H](C)C2,HPK1,active,0.019,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@@H](O)C4)ncc3c(N)c2F)cnc2c1NCCC2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CN(S(C)(=O)=O)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.014,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@@H](N5CCOCC5)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.054,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CN(C(=O)[C@H]5C[C@@H]5F)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.021,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4[C@@H]5COC[C@@H]54)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CC[C@@H]4O)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.021,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@@H](F)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.014,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CN(C5CC5)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.021,Ki,WO2020072695A1,Below 1 nM
CN[C@H]1C[C@H](OC(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)c(N)c3cn2)C1,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4COC[C@H]4C#N)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.058,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@@](C)(C#N)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.015,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@@H](CC#N)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CC[C@](C)(O)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.035,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CC5(C4)CN(CC(F)F)C5)ncc3c(N)c2F)cnc2c1NCCC2,HPK1,active,0.014,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CN(C(=O)[C@H]5C[C@@H]5F)C4)ncc3c(N)c2F)cnc2c1NCCC2,HPK1,active,0.055,Ki,WO2020072695A1,Below 1 nM
CO[C@]1(C)C[C@H](OC(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)c(N)c3cn2)C1,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@@H](N5CC(F)C5)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CN(S(=O)(=O)C5CC5)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.02,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CCC5(CCN(C6COC6)CC5)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.017,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4Cc5nccn5C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CC5(C4)CN(CC(F)F)C5)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CN(S(C)(=O)=O)C4)ncc3c(N)c2F)cnc2c1NCCC2,HPK1,active,0.064,Ki,WO2020072695A1,Below 1 nM
CCC(=O)N1CC(OC(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCC5)c(F)c(N)c3cn2)C1,HPK1,active,0.055,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CCC4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CC(C)(O)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@@H](O)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@@H](C#N)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@@H](C#N)C4)ncc3c(N)c2F)cnc2c1NCCC2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CN(C)C(=O)C4(C)C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.034,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CC(=O)N(C(C)C)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.021,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4COC[C@H]4F)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.034,Ki,WO2020072695A1,Below 1 nM
COCCN1CC(OC(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)c(N)c3cn2)C1,HPK1,active,0.06,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CO[C@@]5(CCN(C)C5)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.031,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CN(C)C[C@@H]4F)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.03,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@H](N(C)C)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
CCc1c(-c2cc3cc(NC(=O)O[C@@H]4CC(=O)N(C)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CC5(C4)CN(C4COC4)C5)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4COC[C@H]4C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
CC(=O)N1CC[C@H](OC(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)c(N)c3cn2)[C@H](F)C1,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC(C)C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.014,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CN(CC(F)F)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4[C@@H]5CN(C)C[C@@H]54)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CC5(CCN(C6COC6)CC5)C4)ncc3c(N)c2F)cnc2c1NCCC2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
CC(=O)N1CC(OC(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCC5)c(F)c(N)c3cn2)C1,HPK1,active,0.028,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CC5(CCN(C)C5)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CC5(CCN(C)CC5)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
CC(=O)N1CC(OC(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)c(N)c3cn2)C1,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CC5(C4)CN(C)C5)ncc3c(N)c2F)cnc2c1NCCC2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
CC(=O)N1CC2(CC(OC(=O)Nc3cc4cc(-c5cnc6c(c5C)NCCO6)c(F)c(N)c4cn3)C2)C1,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CC5(CCN(C)CC5)C4)ncc3c(N)c2F)cnc2c1NCCC2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CCN(CC(F)(F)F)CC4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.023,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CCN(C5COC5)CC4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CN(CC(F)(F)F)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CN(C(C)C)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.061,Ki,WO2020072695A1,Below 1 nM
CC(=O)N1CC[C@@H](OC(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)c(N)c3cn2)C1,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CC5(C4)CN(C)C5)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CCCN(C)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.075,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@]4(C)CC(=O)N(C)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.029,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CCCNC4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.089,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CCN(C)CC4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.03,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CCNCC4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.03,Ki,WO2020072695A1,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,0.027,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1cccc(F)c1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC4)ncc2c(N)n1,HPK1,active,0.02,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC43CC3)ncc2c(N)n1,HPK1,active,0.013,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3ccc(CC#N)cn3)ncc2c(N)n1,HPK1,active,0.033,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cn1cc([C@H]2C[C@@H]2C(=O)Nc2cc3cc(-c4c(Cl)cccc4Cl)nc(N)c3cn2)cn1,HPK1,active,0.049,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1cccc(F)c1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3CC#N)ncc2c(N)n1,HPK1,active,0.099,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1cccc(F)c1-c1cc2cc(NC(=O)[C@@H]3[C@@H](C)[C@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,0.083,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
COCCn1cc([C@@H]2C[C@H]2C(=O)Nc2cc3cc(-c4cnccc4C)nc(N)c3cn2)cn1,HPK1,active,0.02,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccnc(-c2ccccc2)c1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,0.02,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccnc(-c2ccccc2)c1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,0.032,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1nc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3CC#N)cc2c1C1CC1,HPK1,active,0.02,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@]34CCNC(=O)C4)ncc2c(N)n1,HPK1,active,0.02,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
N#CC[C@H]1C[C@@H]1C(=O)Nc1cc2cc(-c3c(Cl)cccc3Cl)nc(N)c2cn1,HPK1,active,0.0675,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cn1cc([C@H]2C[C@@H]2C(=O)Nc2cc3cc(-c4c(F)cccc4Cl)nc(N)c3cn2)cn1,HPK1,active,0.027,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccc(C#N)cc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,0.0692,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccccc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,0.0359,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
NCCOCCn1cc(C2CC2C(=O)Nc2cc3cc(-c4c(Cl)cccc4Cl)nc(N)c3cn2)cn1,HPK1,active,0.026,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnn(CCOCCN)c3)ncc2c(N)n1,HPK1,active,0.0417,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccc(O)cc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,0.078,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3cnn([C@H](C)C#N)c3)ncc2c(N)n1,HPK1,active,0.0675,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
CNC(=O)c1cc(Nc2cc3cc(-c4cnccc4C)nc(N)c3cn2)nn1C,HPK1,active,0.021,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Nc1nc(-c2cnccc2CCO)cc2cc(NC(=O)[C@@H]3C[C@H]3c3cccnc3)ncc12,HPK1,active,0.0892,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3CC#N)ncc2c(N)n1,HPK1,active,0.0219,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Nc1nc(-c2cnccc2CCO)cc2cc(NC(=O)[C@@H]3C[C@H]3c3cnsc3)ncc12,HPK1,active,0.0455,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1nc(N)c2cnc(NC(=O)C3CC3c3cnn(C)c3)cc2c1Cl,HPK1,active,0.078,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3cc(C(C)O)n(C)n3)ncc2c(N)n1,HPK1,active,0.026,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
CC(=O)N1CCC(n2cc(Nc3cc4cc(-c5cnccc5C)nc(N)c4cn3)cn2)C1,HPK1,active,0.02,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3cnn(C(C)C#N)c3)ncc2c(N)n1,HPK1,active,0.0614,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cn1cc([C@@H]2C[C@H]2C(=O)Nc2cc3cc(-c4cnccc4CCO)nc(N)c3cn2)cn1,HPK1,active,0.039,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccnc(-c2ccccc2)c1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3CC#N)ncc2c(N)n1,HPK1,active,0.0509,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1nc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3CC#N)cc2c1C,HPK1,active,0.0881,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1nc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3c3cn[nH]c3)cc2c1Cl,HPK1,active,0.047,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
CC(=O)N1CC(n2cc(Nc3cc4cc(-c5cnccc5C)nc(N)c4cn3)cn2)C1,HPK1,active,0.02,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
CCS(=O)(=O)n1cc([C@H]2C[C@@H]2C(=O)Nc2cc3cc(-c4cnccc4C)nc(N)c3cn2)cn1,HPK1,active,0.02,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cn[nH]c3)ncc2c(N)n1,HPK1,active,0.0629,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
CC[C@@H]1[C@H](C(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)cc3cn2)[C@H]1c1cnn(C)c1,HPK1,active,0.06,Ki,WO2020072627A1_Original_document_20201119122058,Below 1 nM
Cc1c(N)cncc1-c1cc(N)c2nnc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)cc2c1,HPK1,active,0.098,Ki,WO2020069402A1_Original_document_20201120091428,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC54CC4)ncc3c(C)n2)cnc2c1NCCO2,HPK1,active,0.03,Ki,WO2020023551A1_Original_document_20201120101107,Below 1 nM
CNCc1cc(OC)cc2c1CN(c1cccc(-c3nncn3[C@@H](C)CC(F)(F)F)n1)C2=O,HPK1,active,0.5,Ki,WO2021224818A1（HPK1）,Below 1 nM
CC(C)N(C)c1cc2c(c([C@@H](C)N)n1)CN(c1cccc(-c3nnc4n3[C@@H](CF)CC4)n1)C2=O,HPK1,active,0.2,Ki,WO2021220185A1（HPK1）,Below 1 nM
CNCc1nc(N(C)C(C)C)cc2c1CN(c1cccc(-c3nnc4n3[C@@H](C)C[C@H]4C)n1)C2=O,HPK1,active,0.32,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(N(C)C)nc3CNC)C2=O)n1,HPK1,active,0.14,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(N(C)C)cc2c1CN(c1cccc(-c3nnc4n3[C@@H](C)CC4)n1)C2=O,HPK1,active,0.6,Ki,WO2021220185A1（HPK1）,Below 1 nM
CC[C@H]1CCc2nnc(-c3cccc(N4Cc5c(cc(N(C)C)nc5CNC)C4=O)n3)n21,HPK1,active,0.12,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N4CCC[C@H]4C)nc3[C@H](C)N)C2=O)n1,HPK1,active,0.24,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N4CCC[C@H]4C)nc3[C@@H](C)N)C2=O)n1,HPK1,active,0.25,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCn1cnnc1-c1cccc(N2Cc3c(cc(N4CCC[C@H]4C)nc3[C@@H](C)N)C2=O)n1,HPK1,active,0.12,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCn1cnnc1-c1cccc(N2Cc3c(cc(N4CCC[C@H]4C)nc3[C@H](C)N)C2=O)n1,HPK1,active,0.11,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N(C)C(C)C)nc3[C@H](C)N)C2=O)n1,HPK1,active,0.6,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N(C)C(C)C)nc3[C@@H](C)N)C2=O)n1,HPK1,active,0.4,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(N4CCC[C@H]4C)nc3[C@@H](N)CC)C2=O)n1,HPK1,active,0.46,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(N4CCC[C@H]4C)nc3[C@H](N)CC)C2=O)n1,HPK1,active,0.11,Ki,WO2021220185A1（HPK1）,Below 1 nM
CC[C@H](N)c1nc(N2CCC[C@H]2C)cc2c1CN(c1cccc(-c3nncn3CC)n1)C2=O,HPK1,active,0.44,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N(C)C(C)C)nc3C(C)(C)N)C2=O)n1,HPK1,active,0.27,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(N(C)C)nc3[C@@H](C)N)C2=O)n1,HPK1,active,0.96,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(N(C)C)nc3C(N)N)C2=O)n1,HPK1,active,0.75,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N4CCC[C@H]4C)nc3[C@H](C)N)C2=O)n1,HPK1,active,0.22,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N4CCC[C@H]4C)nc3[C@@H](C)N)C2=O)n1,HPK1,active,0.37,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N4CCC[C@H]4C)nc3C(C)(C)N)C2=O)n1,HPK1,active,0.22,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N4CCC[C@H]4C)nc3C(C)(C)N)C2=O)n1,HPK1,active,0.12,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCn1cnnc1-c1cccc(N2Cc3c(cc(N(C)C)nc3C(C)(C)N)C2=O)n1,HPK1,active,0.38,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCN(C)c1cc2c(c([C@H](C)N)n1)CN(c1cccc(-c3nncn3CC)n1)C2=O,HPK1,active,0.4,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCN(C)c1cc2c(c([C@@H](C)N)n1)CN(c1cccc(-c3nncn3CC)n1)C2=O,HPK1,active,0.28,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCN(C)c1cc2c(c(C(C)(C)N)n1)CN(c1cccc(-c3nncn3CC)n1)C2=O,HPK1,active,0.37,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCN(C)c1cc2c(c(C(C)(C)N)n1)CN(c1cccc(-c3nnc(C)n3CC)n1)C2=O,HPK1,active,0.97,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(C4(C)CC4)nc3[C@@H](N)CC)C2=O)n1,HPK1,active,0.78,Ki,WO2021220185A1（HPK1）,Below 1 nM
CC[C@@H](N)c1nc(C2(C)CC2)cc2c1CN(c1cccc(-c3nncn3CC)n1)C2=O,HPK1,active,0.9,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCn1cnnc1-c1cccc(N2Cc3c(cc(C4(C)CC4)nc3[C@H](C)N)C2=O)n1,HPK1,active,0.64,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCn1cnnc1-c1cccc(N2Cc3c(cc(C4(C)CC4)nc3[C@@H](C)N)C2=O)n1,HPK1,active,0.56,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCn1cnnc1-c1cccc(N2Cc3c(cc(C4(C)CC4)nc3C(C)(C)N)C2=O)n1,HPK1,active,0.41,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(C4(C)CC4)nc3[C@H](C)NC)C2=O)n1,HPK1,active,0.67,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCn1cnnc1-c1cccc(N2Cc3c(cc(C4(C)CC4)nc3[C@H](C)NC)C2=O)n1,HPK1,active,0.77,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCn1cnnc1-c1cccc(N2Cc3c(cc(N4CCC[C@H]4C)nc3[C@H](C)NC)C2=O)n1,HPK1,active,0.31,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N4CCC[C@H]4C)nc3[C@H](C)NC)C2=O)n1,HPK1,active,0.61,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(N4CCC[C@H]4C)nc3[C@H](C)N)C2=O)n1,HPK1,active,0.11,Ki,WO2021220185A1（HPK1）,Below 1 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(N4CCC[C@H]4C)nc3[C@@H](C)N)C2=O)n1,HPK1,active,0.17,Ki,WO2021220185A1（HPK1）,Below 1 nM
COC[C@@H](N)c1nc(C2(C)CC2)cc2c1CN(c1cccc(-c3nnc4n3[C@@H](CO)CC4)n1)C2=O,HPK1,active,0.18,Ki,WO2021220185A1（HPK1）,Below 1 nM
COC[C@@H](N)c1nc(C2(C)CC2)cc2c1CN(c1cccc(-c3nnc4n3[C@@H](CF)CC4)n1)C2=O,HPK1,active,0.3,Ki,WO2021220185A1（HPK1）,Below 1 nM
CC[C@@H](N)c1nc(N(C)C)cc2c1CN(c1cccc(-c3nnc4n3[C@@H](CF)CC4)n1)C2=O,HPK1,active,0.21,Ki,WO2021220185A1（HPK1）,Below 1 nM
CC[C@@H](N)c1nc(N(C)C(C)C)cc2c1CN(c1cccc(-c3nnc4n3[C@@H](CF)CC4)n1)C2=O,HPK1,active,0.15,Ki,WO2021220185A1（HPK1）,Below 1 nM
C[C@H](N)c1nc(N2CCC[C@H]2C)cc2c1CN(c1cccc(-c3nnc4n3[C@@H](C)CC4)n1)C2=O,HPK1,active,0.72,Ki,WO2021220185A1（HPK1）,Below 1 nM
C[C@H](N)c1nc(N2CCC[C@H]2C)cc2c1CN(c1cccc(-c3nnc4n3[C@@H](CF)CC4)n1)C2=O,HPK1,active,0.15,Ki,WO2021220185A1（HPK1）,Below 1 nM
CC[C@H]1CCc2nnc(-c3cccc(N4Cc5c(cc(N6CCC[C@H]6C)nc5[C@H](N)CC)C4=O)n3)n21,HPK1,active,0.93,Ki,WO2021220185A1（HPK1）,Below 1 nM
CC[C@H](N)c1nc(N2CCC[C@H]2C)cc2c1CN(c1cccc(-c3nnc4n3[C@@H](C)CC4)n1)C2=O,HPK1,active,0.13,Ki,WO2021220185A1（HPK1）,Below 1 nM
CC[C@@H](N)c1nc(N2CCC[C@H]2C)cc2c1CN(c1cccc(-c3nnc4n3[C@H](C)CC4)n1)C2=O,HPK1,active,0.49,Ki,WO2021220185A1（HPK1）,Below 1 nM
COC[C@@H](N)c1nc(C2(C)CC2)cc2c1CN(c1cccc(-c3nnc4n3[C@@H](C)CC4)n1)C2=O,HPK1,active,0.19,Ki,WO2021220185A1（HPK1）,Below 1 nM
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)[C@@H]3[C@H]4CC(O)C[C@H]43)cc2c1Cl,HPK1,active,0.583,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)[C@@H]3[C@H](C)[C@H]3c3cnn(C)c3)cc2c1,HPK1,active,0.101,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1c(Cl)c(N)c2cnc(Nc3cnn(C(C)C#N)c3)cc2c1Cl,HPK1,active,0.668,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cccc1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3C#N)cc2c1,HPK1,active,0.37,Ki,US2018282282A1（HPK1）,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)C3CC3C#N)ncc2c(N)c1F,HPK1,active,0.333,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C#N)ncc2c(N)c1F,HPK1,active,0.533,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC4)ncc2c(N)c1F,HPK1,active,0.15,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)[C@@H]3[C@@H](c4cnn(C)c4)[C@H]3C)cc2c1,HPK1,active,0.939,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccnc(-c2ccccc2)c1-c1cc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)cc2c1,HPK1,active,0.137,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccnc(-c2ccccc2)c1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3c3cnn(C)c3)cc2c1,HPK1,active,0.584,Ki,WO2018183964A1(1),Below 1 nM
C[C@H]1COC(=O)N1c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@@H]3F)cc2c1,HPK1,active,0.25,Ki,WO2018183964A1(1),Below 1 nM
CCc1ccncc1-c1cc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3C#N)cc2c1,HPK1,active,0.823,Ki,WO2018183964A1(1),Below 1 nM
N#C[C@@H]1C[C@H]1C(=O)Nc1cc2cc(-c3cnccc3CCO)cc(N)c2cn1,HPK1,active,0.738,Ki,WO2018183964A1(1),Below 1 nM
Cc1cc2[nH]c(=O)oc2cc1-c1cc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3C#N)cc2c1,HPK1,active,0.624,Ki,WO2018183964A1(1),Below 1 nM
CC1COC(=O)N1c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@@H]3F)cc2c1,HPK1,active,0.351,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)C3CC3)ncc2c(N)c1F,HPK1,active,0.333,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C3CC3)cc2c1,HPK1,active,0.391,Ki,WO2018183964A1(1),Below 1 nM
Cn1cc([C@H]2C[C@@H]2C(=O)Nc2cc3cc(-c4c(F)cccc4F)cc(N)c3cn2)cn1,HPK1,active,0.844,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc(N)c2cnc(Nc3cnn(C(C)C#N)c3)cc2c1Cl,HPK1,active,0.363,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc(N)c2cnc(Nc3cnn([C@H](C)C#N)c3)cc2c1,HPK1,active,0.253,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3cnn([C@H](C)C#N)c3)ncc2c(N)c1Cl,HPK1,active,0.485,Ki,US2018282282A1（HPK1）,Below 1 nM
Cc1ccncc1-c1cc(N)c2cnc(Nc3cnn([C@@H](C)C#N)c3)cc2c1,HPK1,active,0.299,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@H](C)[C@H]3c3cnn(C)c3)ncc2c(N)c1F,HPK1,active,0.273,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3cnn([C@H](C)C#N)c3)ncc2c(N)c1F,HPK1,active,0.79,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3cnn([C@@H](C)C#N)c3)ncc2c(N)c1F,HPK1,active,0.148,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@@H](c4cnn(C)c4)[C@H]3C)ncc2c(N)c1F,HPK1,active,0.21,Ki,WO2018183964A1(1),Below 1 nM
Nc1cc(-c2cncc3c2CCN3)cc2cc(NC(=O)C3CC3)ncc12,HPK1,active,0.312,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(-c2cc(N)c3cnc(NC(=O)[C@H]4C[C@@H]4c4cnn(C)c4)cc3c2)ccnc1N,HPK1,active,0.541,Ki,WO2018183964A1(1),Below 1 nM
CC(C)[C@H]1COC(=O)N1c1cc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3C#N)cc2c1,HPK1,active,0.204,Ki,US2018282282A1（HPK1）,Below 1 nM
Cc1c(N)cncc1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3C#N)cc2c1,HPK1,active,0.37,Ki,WO2018183964A1(1),Below 1 nM
CC(C)NC(=O)Nc1cc2cc(N3C(=O)OCC3C)cc(N)c2cn1,HPK1,active,0.26,Ki,WO2018183964A1(1),Below 1 nM
CC1COC(=O)N1c1cc(N)c2cnc(NC(=O)C3CC3F)cc2c1,HPK1,active,0.191,Ki,US2018282282A1（HPK1）,Below 1 nM
CC(C)C1COC(=O)N1c1cc(N)c2cnc(NC(=O)C3CC3C#N)cc2c1,HPK1,active,0.204,Ki,WO2018183964A1(1),Below 1 nM
Cc1cc2[nH]c(=O)oc2cc1-c1cc(N)c2cnc(NC(=O)C3CC3C#N)cc2c1,HPK1,active,0.205,Ki,WO2018183964A1(1),Below 1 nM
CC(C)c1[nH]ncc1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@@H]3F)cc2c1,HPK1,active,0.366,Ki,WO2018183964A1(1),Below 1 nM
CCc1c(N)cncc1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@@H]3F)cc2c1,HPK1,active,0.167,Ki,WO2018183964A1(1),Below 1 nM
CC(C)c1[nH]ncc1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3F)cc2c1,HPK1,active,0.627,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)C3CC3)ncc2c(N)c1C#N,HPK1,active,0.209,Ki,WO2018183964A1(1),Below 1 nM
CCN(C)c1cc2c(c(CNC)n1)CN(c1cccc(-c3nncn3CC)n1)C2=O,HPK1,active,0.11,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCc1nnc(-c2cccc(N3Cc4c(cc(N5CCC[C@H]5C)nc4CN)C3=O)n2)n1CC,HPK1,active,0.79,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CCCn1c(CC)nnc1-c1cccc(N2Cc3c(cc(N4CCC[C@H]4C)nc3CNC)C2=O)n1,HPK1,active,0.94,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
C[C@H]1COC(=O)N1c1cccc(N2Cc3c(cc(N4[C@H](C)CC[C@H]4C)nc3CN)C2=O)n1,HPK1,active,0.28,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CCn1cnnc1-c1cccc(N2Cc3c(cc(C4(C)CC4)nc3CNC)C2=O)n1,HPK1,active,0.51,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(N2[C@@H](C)CC[C@H]2C)cc2c1CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,0.19,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(N(C)C)cc2c1CN(c1cccc(-c3nncn3[C@H](C)C(C)C)n1)C2=O,HPK1,active,0.37,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CNCc1nc(C2(C)CC2)cc2c1CN(c1cccc(-c3nncn3C3CCCC3)n1)C2=O,HPK1,active,0.47,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(N(C)C)cc2c1CN(c1cccc(C3=NN=CC3[C@@H](C)C(C)C)n1)C2=O,HPK1,active,0.17,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CNCc1nc(N(C)C)cc2c1CN(c1cccc(-c3nncn3CC(C)C)n1)C2=O,HPK1,active,0.26,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CN(C)c1cc2c(c(CN)n1)CN(c1cccc(N3C(=O)OC[C@@H]3CF)n1)C2=O,HPK1,active,0.37,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CCCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N(C)C(C)C)nc3CN)C2=O)n1,HPK1,active,0.55,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCN(C)c1cc2c(c(CN)n1)CN(c1cccc(-c3nnc(C)n3CC)n1)C2=O,HPK1,active,0.34,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N(CC)CC)nc3CN)C2=O)n1,HPK1,active,0.36,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
Cc1nnc(-c2cccc(N3Cc4c(cc(N5[C@H](C)CC[C@H]5C)nc4CN)C3=O)n2)n1C(C)C,HPK1,active,0.95,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N4[C@H](C)CC[C@H]4C)nc3CN)C2=O)n1,HPK1,active,0.76,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CCN(c1cc2c(c(CN)n1)CN(c1cccc(-c3nnc(C)n3CC)n1)C2=O)C(C)C,HPK1,active,0.7,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCC(CC)n1cnnc1-c1cccc(N2Cc3c(cc(N(CC)C(C)C)nc3CN)C2=O)n1,HPK1,active,0.5,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
Cc1nnc(-c2cccc(N3Cc4c(cc(N(C)C(C)C)nc4CN)C3=O)n2)n1C(C)C,HPK1,active,0.28,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
Cc1nnc(-c2cccc(N3Cc4c(cc(N5CCCC5(C)C)nc4CN)C3=O)n2)n1C(C)C,HPK1,active,0.1,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCN(CC)c1cc2c(c(CN)n1)CN(c1cccc(-c3nnc(C)n3CC)n1)C2=O,HPK1,active,0.88,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
Cc1nnc(-c2cccc(N3Cc4c(cc(N5CCC[C@@H]5C)nc4CN)C3=O)n2)n1C(C)C,HPK1,active,0.19,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N(C)CC)nc3CN)C2=O)n1,HPK1,active,0.68,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCN(C)c1cc2c(c(CN)n1)CN(c1cccc(-c3nnc(C)n3C(C)C)n1)C2=O,HPK1,active,0.48,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N(C)C(C)C)nc3CN)C2=O)n1,HPK1,active,0.38,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N4CCC[C@@H]4C)nc3CN)C2=O)n1,HPK1,active,0.18,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
Cc1nnc(-c2cccc(N3Cc4c(cc(N5CCC[C@H]5C)nc4CN)C3=O)n2)n1C(C)C,HPK1,active,0.76,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N4CCCC4(C)C)nc3CN)C2=O)n1,HPK1,active,0.16,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N4CCCC4(C)C)nc3CN)C2=O)n1,HPK1,active,0.15,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCC(CC)n1cnnc1-c1cccc(N2Cc3c(cc(N(C)CC)nc3CN)C2=O)n1,HPK1,active,0.14,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCC(CC)n1cnnc1-c1cccc(N2Cc3c(cc(N4CCCC4(C)C)nc3CN)C2=O)n1,HPK1,active,0.1,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(N(CC)C(C)C)nc3CN)C2=O)n1,HPK1,active,0.91,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCN(c1cc2c(c(CN)n1)CN(c1cccc(-c3nncn3C(C)C)n1)C2=O)C(C)C,HPK1,active,0.47,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCC(CC)n1cnnc1-c1cccc(N2Cc3c(cc(C4CC4)nc3CNC)C2=O)n1,HPK1,active,0.52,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCN(c1cc2c(c(CN)n1)CN(c1cccc(-c3nncn3CC)n1)C2=O)C(C)C,HPK1,active,0.74,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CC[C@@H](C)n1cnnc1-c1cccc(N2Cc3c(cc(C4(C)CC4)nc3CNC)C2=O)n1,HPK1,active,0.16,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(N4[C@H](C)CC[C@H]4C)nc3CN)C2=O)n1,HPK1,active,0.73,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CCCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N4CCC[C@@H]4C)nc3CN)C2=O)n1,HPK1,active,0.47,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N4CCC[C@H]4C)nc3CN)C2=O)n1,HPK1,active,0.28,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
C[C@H]1CCCN1c1cc2c(c(CN)n1)CN(c1cccc(N3C(=O)OC[C@@H]3C)n1)C2=O,HPK1,active,0.2,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CCCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N(C)CC)nc3CNC)C2=O)n1,HPK1,active,0.78,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCC(CC)n1cnnc1-c1cccc(N2Cc3c(cc(C4CC4)nc3CN)C2=O)n1,HPK1,active,0.31,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCC(CC)n1cnnc1-c1cccc(N2Cc3c(cc(C4(C)CC4)nc3CN)C2=O)n1,HPK1,active,0.8,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
C[C@H]1COC(=O)N1c1cccc(N2Cc3c(cc(N4CCC[C@H]4C)nc3CN)C2=O)n1,HPK1,active,0.1,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CCC(CC)n1cnnc1-c1cccc(N2Cc3c(cc(N(CC)CC)nc3CN)C2=O)n1,HPK1,active,0.41,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCC(CC)n1cnnc1-c1cccc(N2Cc3c(cc(N4[C@H](C)CC[C@H]4C)nc3CN)C2=O)n1,HPK1,active,0.52,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CNCc1nc(N2[C@H](C)CC[C@H]2C)cc2c1CN(c1cccc(N3C(=O)OC[C@@H]3CF)n1)C2=O,HPK1,active,0.89,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CCC(CC)n1cnnc1-c1cccc(N2Cc3c(cc(N(C)C)nc3CN)C2=O)n1,HPK1,active,0.46,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCn1cnnc1-c1cccc(N2Cc3c(cc(N4[C@H](C)CC[C@H]4C)nc3CN)C2=O)n1,HPK1,active,0.32,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CCn1cnnc1-c1cccc(N2Cc3c(cc(N4[C@H](C)CC[C@H]4C)nc3CNC)C2=O)n1,HPK1,active,0.26,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(N4[C@H](C)CC[C@H]4C)nc3CNC)C2=O)n1,HPK1,active,0.21,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CNCc1nc(N2CCC[C@H]2C)cc2c1CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,0.13,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
[2H]C([2H])([2H])C([2H])([2H])N(c1cc2c(c(CNC)n1)CN(c1cccc(-c3nncn3CC)n1)C2=O)C([2H])([2H])C([2H])([2H])[2H],HPK1,active,0.29,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CCn1cnnc1-c1cccc(N2Cc3c(cc(C4CCC4)nc3CNC)C2=O)n1,HPK1,active,0.94,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(N(CC)C(C)C)nc3CNC)C2=O)n1,HPK1,active,0.83,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCN(CC)c1cc2c(c(CNC)n1)CN(c1cccc(-c3nnc(C)n3CC)n1)C2=O,HPK1,active,0.34,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCN(CC)c1cc2c(c(CNC)n1)CN(c1cccc(-c3cnc(C)n3CC)n1)C2=O,HPK1,active,0.4,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(C4(C)CC4)nc3CNC)C2=O)n1,HPK1,active,0.34,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCn1cnnc1-c1cccc(N2Cc3c(cc(N4CCC4)nc3CNC)C2=O)n1,HPK1,active,0.43,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(C2(C)CC2)cc2c1CN(c1cccc(N3C(=O)OC[C@@H]3CF)n1)C2=O,HPK1,active,0.33,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCN(c1cc2c(c(CNC)n1)CN(c1cccc(-c3nncn3CC)n1)C2=O)C(C)C,HPK1,active,0.14,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(N(C)C(C)C)nc3CN)C2=O)n1,HPK1,active,0.12,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(N(CC)CC)nc3CNC)C2=O)n1,HPK1,active,0.16,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(NC(C)C)cc2c1CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,0.73,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCNc1cc2c(c(CNC)n1)CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,0.68,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCN(CC)c1cc2c(c(CN)n1)CN(c1cccc(-c3nncn3CC)n1)C2=O,HPK1,active,0.52,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCn1cnnc1-c1cccc(N2Cc3c(cc(N(C)C(C)C)nc3CNC)C2=O)n1,HPK1,active,0.18,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCN(c1cc2c(c(CNC)n1)CN(c1cccc(-c3nncn3C(C)C)n1)C2=O)C(C)C,HPK1,active,0.16,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(C2CCC2)cc2c1CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,0.53,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCc1nnc(-c2cccc(N3Cc4c(cc(N5CCC[C@H]5C)nc4CNC)C3=O)n2)n1CC,HPK1,active,0.52,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CNCc1nc(C2(C)CC2)cc2c1CN(c1cccc(-c3nncn3C3CCC3)n1)C2=O,HPK1,active,0.35,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N(C)C(C)C)nc3CNC)C2=O)n1,HPK1,active,0.17,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(N(C)C(C)C)cc2c1CN(c1cccc(-c3nncn3C)n1)C2=O,HPK1,active,0.58,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N4CCC[C@H]4C)nc3CN)C2=O)n1,HPK1,active,0.23,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCN(C)c1cc2c(c(CN)n1)CN(c1cccc(-c3nncn3CC)n1)C2=O,HPK1,active,0.17,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(N(C)CC)nc3CNC)C2=O)n1,HPK1,active,0.19,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CC[C@H](C)n1cnnc1-c1cccc(N2Cc3c(cc(C4(C)CC4)nc3CNC)C2=O)n1,HPK1,active,0.46,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCC(CC)n1cnnc1-c1cccc(N2Cc3c(cc(C4(C)CC4)nc3CNC)C2=O)n1,HPK1,active,0.21,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(N(C)CC)nc3CN)C2=O)n1,HPK1,active,0.34,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1cc(N2[C@@H](C)C[C@H]2C)cc2c1CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,0.61,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(N)cc2c1CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,0.14,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCN(C)c1cc2c(c(CNC)n1)CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,0.14,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(N(C)C)cc2c1CN(c1cccc(N3C(=O)OC[C@@H]3CF)n1)C2=O,HPK1,active,0.17,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
C[C@H]1COC(=O)N1c1cccc(N2Cc3c(cc(N4CCC4)nc3CN)C2=O)n1,HPK1,active,0.4,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
C[C@H]1COC(=O)N1c1cccc(N2Cc3c(cc(C4(C)CC4)nc3CN)C2=O)n1,HPK1,active,0.33,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(C2CC2)cc2c1CN(c1cccc(N3C(=O)OC[C@@H]3C)n1)C2=O,HPK1,active,0.81,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCN(CC)c1cc2c(c(CN)n1)CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,0.38,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CC(C)c1cnnn1-c1cccc(N2Cc3c(cc(N(C)C)nc3CN)C2=O)n1,HPK1,active,0.12,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(N2CCC2)cc2c1CN(c1cccc(N3C(=O)OC[C@@H]3C)n1)C2=O,HPK1,active,0.28,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
C[C@H]1COC(=O)N1c1cccc(N2Cc3c(cc(N(C)C)nc3CN)C2=O)n1,HPK1,active,0.34,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CC(C)n1cnnc1-c1cccc(N2Cc3c(cc(C4CC4)nc3CN)C2=O)n1,HPK1,active,0.66,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
C[C@H]1COC(=O)N1c1cccc(N2Cc3c(cc(C4CC4)nc3CN)C2=O)n1,HPK1,active,0.9,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(NC)cc2c1CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,0.72,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(N(C)C)cc2c1CN(c1ccc(F)c(-c3cn[nH]c3C(C)C)n1)C2=O,HPK1,active,0.4,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(N(C)C)cc2c1CN(c1cccc(-c3nncn3CC3CC3)n1)C2=O,HPK1,active,0.62,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CN(C)c1cc2c(c(CN)n1)CN(c1cccc(-c3nncn3CC3CC3)n1)C2=O,HPK1,active,0.56,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CC[C@H](C)C1C=NN=C1c1cccc(N2Cc3c(cc(N(C)C)nc3CNC)C2=O)n1,HPK1,active,0.17,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CC(C)n1cnnc1-c1cccc(N2Cc3c(cc(N(C)C)nc3CN)C2=O)n1,HPK1,active,0.2,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(N(C)C)cc2c1CN(c1cccc(N3C(=O)OC[C@@H]3C)n1)C2=O,HPK1,active,0.26,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CCN(CC)c1cc2c(c(CNC)n1)CN(c1cccc(-c3nncn3CC)n1)C2=O,HPK1,active,0.27,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(N2[C@H](C)CC[C@H]2C)cc2c1CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,0.25,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CNCc1nc(N(C)C(C)C)cc2c1CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,0.13,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(C2CC2)cc2c1CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,0.39,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCN(CC)c1cc2c(c(CNC)n1)CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,0.39,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(N2[C@H](C)C[C@H]2C)cc2c1CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,0.41,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(N2CCC2)cc2c1CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,0.28,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(N(C)C)cc2c1CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,0.15,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3cnn(C(C)C)c3)ncc2c(N)c1Cl,HPK1,active,0.485,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3C=N)cc2c1,HPK1,active,0.68,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)[C@@H]3[C@@H](CC#N)[C@H]3C)cc2c1,HPK1,active,0.187,Ki,WO2018183964A1(1),Below 1 nM
CC(C)C1COC(=O)N1c1cc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3C#N)cc2c1,HPK1,active,0.204,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc(N)c2cnc(NC(=O)C3CC3C#N)cc2c1,HPK1,active,0.37,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CS(=O)(=O)N(C)C5)ncc3cc2F)cnc2c1NCC[C@@H]2O,HPK1,active,0.457,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC5)ncc3cc2F)cnc2c1NCC(C)(C)[C@@H]2O,HPK1,active,0.11,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc(F)c3cnc(Nc4cc5n(n4)CC(=O)N(C)CC54CC4)cc3c2)cnc2c1NCC[C@H]2O,HPK1,active,0.319,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc(S)c3cnc(Nc4cc5n(n4)CC(=O)N(C)CC54CC4)cc3c2)cnc2c1NCC[C@@H]2O,HPK1,active,0.332,Ki,WO2020023560A1,Below 1 nM
COC1CCNc2c1ncc(-c1cc(F)c3cnc(Nc4cc5n(n4)CC(=O)N(C)CC5)cc3c1)c2C,HPK1,active,0.46,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc(F)c3cnc(Nc4cc5n(n4)CC(=O)N(C)CC5)cc3c2)cnc2c1NCC[C@]2(C)O,HPK1,active,0.38,Ki,WO2020023560A1,Below 1 nM
Cc1ncc(-c2cc(F)c3cnc(Nc4cc5n(n4)CC(=O)NCC5)cc3c2)c(C)c1N,HPK1,active,0.155,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)NCC5)ncc3cc2F)cnc2c1NCCOC2,HPK1,active,0.793,Ki,WO2020023560A1,Below 1 nM
Cc1c(CS(C)(=O)=O)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC4)ncc2cc1F,HPK1,active,0.18,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)NCC5)ncc3cc2F)cnc2c1NCCC2O,HPK1,active,0.11,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)NCC5)ncc3cc2F)cnc2c1NCCC2=O,HPK1,active,0.1,Ki,WO2020023560A1,Below 1 nM
Cc1c[nH]c2c(C)c(-c3cc4cc(Nc5cc6n(n5)CC(=O)N(C)CC6)ncc4cc3F)cnc12,HPK1,active,0.26,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC5)ncc3cc2F)cnnc1N,HPK1,active,0.83,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC5)ncc3cc2F)cnc2c1CCCO2,HPK1,active,0.24,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)Cc4nccn4CC5)ncc3cc2F)cnc2c1NCCS2=O,HPK1,active,0.48,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC5)ncc3cc2F)cnc2c1NCN(C)C2=O,HPK1,active,0.25,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC5)ncc3cc2F)cnc2cn[nH]c12,HPK1,active,0.12,Ki,WO2020023560A1,Below 1 nM
Cc1c(NC2CNC2)cncc1-c1cc2cc(Nc3cc4n(n3)Cc3nccn3CC4)ncc2cc1F,HPK1,active,0.5,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC5)ncc3cc2F)cnc2c1NCCS2(=O)=O,HPK1,active,0.277,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)NCC5)ncc3cc2F)cnc2c1NCC(F)(F)O2,HPK1,active,0.161,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC5)ncc3cc2F)cnc2nc[nH]c12,HPK1,active,0.14,Ki,WO2020023560A1,Below 1 nM
Cc1c(NS(C)(=O)=O)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC4)ncc2cc1F,HPK1,active,0.46,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)ncc2cc1C#N,HPK1,active,0.39,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC3=NOC(C)(C)N3CC4)ncc2cc1F,HPK1,active,0.12,Ki,WO2020023560A1,Below 1 nM
Cc1ncc(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C(C)C)CC5F)ncc3cc2F)c(C)c1N,HPK1,active,0.15,Ki,WO2020023560A1,Below 1 nM
Cc1ncc(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C(C)C)CC5)ncc3cc2F)c(C)c1N,HPK1,active,0.148,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C(C)C)CC5)ncc3cc2F)cnc2c1NC(=O)CO2,HPK1,active,0.11,Ki,WO2020023560A1,Below 1 nM
Cc1c(N)cncc1-c1cc(Cl)c2cnc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)cc2c1,HPK1,active,0.64,Ki,WO2020023560A1,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C(C)C)CC5)ncc3c(Cl)c2F)cnc2c1NCCO2,HPK1,active,0.2,Ki,WO2020023560A1,Below 1 nM
[2H]C([2H])([2H])C([2H])([2H])C(c1cc2c(c(CNC)n1)CN(c1cccc(-c3nncn3CC)n1)C2=O)C([2H])([2H])C([2H])([2H])[2H],HPK1,active,0.29,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(N2CCC[C@@H]2C)cc2c1CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,0.13,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCc1nnc(-c2cccc(N3Cc4c(cc(N5CCC[C@@H]5C)nc4CN)C3=O)n2)n1CC,HPK1,active,0.79,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CC[C@@H](CO)n1cnnc1-c1cccc(N2Cc3c(cc(C4(C)CC4)nc3CNC)C2=O)n1,HPK1,active,0.35,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(N(C)C)cc2c1CN(c1cccc(-c3nncn3[C@@H](C)C(C)C)n1)C2=O,HPK1,active,0.37,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CC[C@@H](CC(F)(F)F)n1cnnc1-c1cccc(N2Cc3c(cc(C4(C)CC4)nc3CNC)C2=O)n1,HPK1,active,0.13,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(N(C)C)cc2c1CN(c1cccc(C3=NN=CC3[C@H](C)C(C)C)n1)C2=O,HPK1,active,0.17,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCc1nc(N2CCC[C@@H]2C)cc2c1CN(c1cccc(-c3nnc(CC)n3CC(C)C)n1)C2=O,HPK1,active,0.22,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCCn1c(CC)nnc1-c1cccc(N2Cc3c(cc(N4CCC[C@@H]4C)nc3CNC)C2=O)n1,HPK1,active,0.94,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CN(C)c1cc2c(c(CN)n1)CN(c1cccc(N3C(=O)OC[C@H]3CF)n1)C2=O,HPK1,active,0.37,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
Cc1nnc(-c2cccc(N3Cc4c(cc(N5[C@@H](C)CC[C@@H]5C)nc4CN)C3=O)n2)n1C(C)C,HPK1,active,0.95,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N4[C@@H](C)CC[C@@H]4C)nc3CN)C2=O)n1,HPK1,active,0.76,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
C[C@H]1CC[C@H](C)N1c1cc2c(c(CN)n1)CN(c1cccc(N3C(=O)OC[C@H]3C)n1)C2=O,HPK1,active,0.28,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(N4[C@@H](C)CC[C@@H]4C)nc3CN)C2=O)n1,HPK1,active,0.73,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCC(CC)n1c(C)nnc1-c1cccc(N2Cc3c(cc(N4CCC[C@H]4C)nc3CNC)C2=O)n1,HPK1,active,0.8,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
C[C@@H]1CCCN1c1cc2c(c(CN)n1)CN(c1cccc(N3C(=O)OC[C@H]3C)n1)C2=O,HPK1,active,0.2,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
C[C@H]1CCCN1c1cc2c(c(CN)n1)CN(c1cccc(N3C(=O)OC[C@H]3C)n1)C2=O,HPK1,active,0.1,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCC(CC)n1cnnc1-c1cccc(N2Cc3c(cc(N4[C@@H](C)CC[C@@H]4C)nc3CN)C2=O)n1,HPK1,active,0.52,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(N2[C@@H](C)CC[C@@H]2C)cc2c1CN(c1cccc(N3C(=O)OC[C@H]3CF)n1)C2=O,HPK1,active,0.89,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCn1cnnc1-c1cccc(N2Cc3c(cc(N4[C@@H](C)CC[C@@H]4C)nc3CN)C2=O)n1,HPK1,active,0.32,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCn1cnnc1-c1cccc(N2Cc3c(cc(N4[C@@H](C)CC[C@@H]4C)nc3CNC)C2=O)n1,HPK1,active,0.26,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(N4[C@@H](C)CC[C@@H]4C)nc3CNC)C2=O)n1,HPK1,active,0.21,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCN(c1cc2c(c(CNC)n1)CN(c1cccc(N3C(=O)OC[C@H]3CF)n1)C2=O)C(C)C,HPK1,active,0.96,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCc1nnc(-c2cccc(N3Cc4c(cc(N5CCC[C@@H]5C)nc4CNC)C3=O)n2)n1CC,HPK1,active,0.52,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CC[C@@H](C)n1cnnc1-c1cccc(N2Cc3c(cc(N(C)C)nc3CNC)C2=O)n1,HPK1,active,0.17,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(N(C)C)cc2c1CN(c1cccc(N3C(=O)OC[C@H]3C)n1)C2=O,HPK1,active,0.26,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(N2[C@@H](C)CC[C@@H]2C)cc2c1CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,0.25,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CNCc1nc(N2[C@@H](C)C[C@@H]2C)cc2c1CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,0.77,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CCN([C@@H]5CCOC5)C[C@@H]4F)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.254,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CCN([C@H]5CCOC5)C[C@@H]4F)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.277,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CC[C@H]4C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.14,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4COC[C@@H]4C)ncc3c(N)c2F)cnc2c1NC(=O)CO2,HPK1,active,0.9,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@]4(C)C[C@H](O)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.253,Ki,WO2020072695A1,Below 1 nM
CC[C@@H]1COC[C@H]1OC(=O)Nc1cc2cc(-c3cnc4c(c3C)NCCO4)c(F)c(N)c2cn1,HPK1,active,0.105,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CCO[C@@H]4C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.308,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CCO[C@H]4C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.395,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CC(=O)N(C)C4)ncc3c(N)c2F)cnc2c1NCCC2,HPK1,active,0.184,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4COC[C@H]4F)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.15,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CCOCC4)ncc3c(N)c2F)cnc2c1NCC[C@H]2C,HPK1,active,0.891,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4COC[C@@H]4C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.32,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4COC[C@H]4C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.16,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4COC[C@@H]4C)ncc3c(N)c2F)cnc2c1NC[C@@H](F)O2,HPK1,active,0.119,Ki,WO2020072695A1,Below 1 nM
CNc1cncc(-c2cc3cc(NC(=O)O[C@H]4C[C@@](C)(O)C4)ncc3c(N)c2F)c1C,HPK1,active,0.216,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CC[C@H]4O)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.33,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CCN(CC(F)F)C[C@H]4F)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.149,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CN(C)C[C@H]4F)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.17,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@@H](O)C4)ncc3c(N)c2F)cnc2c1NC[C@H](C)C2,HPK1,active,0.32,Ki,WO2020072695A1,Below 1 nM
CO[C@@H]1COCC[C@H]1OC(=O)Nc1cc2cc(-c3cnc4c(c3C)NCCO4)c(F)c(N)c2cn1,HPK1,active,0.72,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4Cc5ncnn5C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.15,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CN(C(=O)[C@@H]5C[C@H]5F)C4)ncc3c(N)c2F)cnc2c1NCCC2,HPK1,active,0.152,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H](C)CO)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.11,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CN(C)C(=O)C4(C)C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.28,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CN(C)C[C@H]4C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.154,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CN(C)C[C@H]4C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.201,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CCOCC4)ncc3c(N)c2F)cnc2c1[C@@H](O)CCO2,HPK1,active,0.29,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CCN(C)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.25,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N4CC(C)(O)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.205,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N(C)C4CCC4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.52,Ki,WO2020072695A1,Below 1 nM
CO[C@@H]1COCC[C@@H]1NC(=O)Nc1cc2cc(-c3cnc4c(c3C)NCCO4)c(F)c(N)c2cn1,HPK1,active,0.96,Ki,WO2020072695A1,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(NC(=O)NC3CCCC3)ncc2c(N)c1F,HPK1,active,0.102,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N4CCCC4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.29,Ki,WO2020072695A1,Below 1 nM
CO[C@@H]1COC[C@@H]1NC(=O)Nc1cc2cc(-c3cnc4c(c3C)NCCO4)c(F)c(N)c2cn1,HPK1,active,0.469,Ki,WO2020072695A1,Below 1 nM
CNC(=O)Nc1cc2cc(-c3cnc4c(c3C)NCCC4)c(F)c(N)c2cn1,HPK1,active,0.15,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@@H](O)C4)ncc3c(N)c2F)cnc2c1NC[C@@H]1C[C@H]21,HPK1,active,0.14,Ki,WO2020072695A1,Below 1 nM
CO[C@H]1COCC[C@@H]1OC(=O)Nc1cc2cc(-c3cnc4c(c3C)NCCO4)c(F)c(N)c2cn1,HPK1,active,0.12,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CCOC4)ncc3c(N)c2F)cnc2c1NCC(CO)C2,HPK1,active,0.43,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CCS(=O)(=O)CC4)ncc3c(N)c2F)cnc2c1NCCC2,HPK1,active,0.85,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CO[C@@H]5OCC[C@@H]54)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.185,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4COC[C@@H]4C)ncc3c(N)c2F)cnc2c1NC[C@H](F)O2,HPK1,active,0.33,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CCN(CC(F)F)C[C@@H]4F)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.293,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CO[C@H]5COC[C@@H]45)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.219,Ki,WO2020072695A1,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(NC(=O)O[C@H]3COC[C@@H]3C)ncc2c(N)c1F,HPK1,active,0.138,Ki,WO2020072695A1,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(NC(=O)O[C@H]3C[C@@H](C#N)C3)ncc2c(N)c1F,HPK1,active,0.14,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H](C)CO)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.26,Ki,WO2020072695A1,Below 1 nM
CNc1cncc(-c2cc3cc(NC(=O)O[C@H]4C[C@](C)(O)C4)ncc3c(N)c2F)c1C,HPK1,active,0.538,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H](C)CN(C)C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.85,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CN(CCF)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.11,Ki,WO2020072695A1,Below 1 nM
CCN1C[C@H](OC(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)c(N)c3cn2)CC1=O,HPK1,active,0.25,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CN(C)CCN(C)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.46,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC[C@@]4(F)CCN(C)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.14,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OCC4(F)CN(C)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.13,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4COCCN(C)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.277,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CCN(C)CC4(C)C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.187,Ki,WO2020072695A1,Below 1 nM
CC(=O)N[C@H]1CCCC[C@@H]1OC(=O)Nc1cc2cc(-c3cnc4c(c3C)NCCO4)c(F)c(N)c2cn1,HPK1,active,0.59,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CCOCC4)ncc3c(N)c2F)cnc2c1NCCC2O,HPK1,active,0.65,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CCN(C)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.2,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CC5COCC(C4)N5C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.4,Ki,WO2020072695A1,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CN(C)C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.11,Ki,WO2020072695A1,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3C)ncc2c(N)n1,HPK1,active,0.48,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1cccc(F)c1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,0.47,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1cccc(Cl)c1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3CC#N)ncc2c(N)n1,HPK1,active,0.41,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1cccc(F)c1-c1cc2cc(NC(=O)[C@@H]3[C@H](C)[C@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,0.3,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@H](C)[C@H]3CC#N)ncc2c(N)n1,HPK1,active,0.188,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C#N)ncc2c(N)n1,HPK1,active,0.4,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C#N)ncc2c(N)n1,HPK1,active,0.343,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,0.55,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1nc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3c3cn[nH]c3)cc2c1F,HPK1,active,0.2,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3CC#N)ncc2c(N)n1,HPK1,active,0.57,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccnc(Cc2ccccc2)c1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,0.78,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3cc4n(n3)[C@H](C#N)COC4)ncc2c(N)n1,HPK1,active,0.27,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3cc4n(n3)[C@@H](C#N)COC4)ncc2c(N)n1,HPK1,active,0.97,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC4)ncc2c(N)n1,HPK1,active,0.21,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1nc2c(=O)n(C)ncc2cc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,0.74,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccnc(Cc2ccccc2)c1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,0.25,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
COc1cc(C)c(-c2cc3cc(NC(=O)[C@H]4C[C@@H]4c4cnn(C)c4)ncc3c(N)n2)cn1,HPK1,active,0.29,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1cc(-c2ncco2)ccc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,0.69,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cn1cc([C@@H]2C[C@H]2C(=O)Nc2cc3cc(-c4c(Cl)cccc4Cl)nc(N)c3cn2)cn1,HPK1,active,0.66,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccc(C#N)cc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3CC#N)ncc2c(N)n1,HPK1,active,0.46,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccccc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3CC#N)ncc2c(N)n1,HPK1,active,0.22,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1c(N)cccc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3CC#N)ncc2c(N)n1,HPK1,active,0.53,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1c(N)ccc(Cl)c1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3CC#N)ncc2c(N)n1,HPK1,active,0.17,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1cc(C(N)=O)cc(F)c1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,0.33,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
COC(=O)c1cc(C)c(-c2cc3cc(NC(=O)[C@H]4C[C@@H]4c4cnn(C)c4)ncc3c(N)n2)cn1,HPK1,active,0.509,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cn1cc([C@@H]2C[C@H]2C(=O)Nc2cc3c(Cl)c(-c4cnccc4CCO)nc(N)c3cn2)cn1,HPK1,active,0.432,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C3CCOCC3)ncc2c(N)n1,HPK1,active,0.48,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1nc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3CC#N)cc2c1C1CC1,HPK1,active,0.522,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1cc(-c2ncco2)ncc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,0.184,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cn1cc([C@H]2C[C@@H]2C(=O)Nc2cc3cc(-c4c(F)cccc4F)nc(N)c3cn2)cn1,HPK1,active,0.112,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cn1cc([C@H]2C[C@@H]2C(=O)Nc2cc3cc(-c4ccccc4Cl)nc(N)c3cn2)cn1,HPK1,active,0.152,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cn1cc([C@@H]2C[C@H]2C(=O)Nc2cc3cc(-c4c(F)cccc4Cl)nc(N)c3cn2)cn1,HPK1,active,0.65,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccccc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,0.932,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)C3C4CC(N5CCOCC5)CC43)ncc2c(N)n1,HPK1,active,0.972,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
NCCOCCn1cc([C@H]2C[C@@H]2C(=O)Nc2cc3cc(-c4c(Cl)cccc4Cl)nc(N)c3cn2)cn1,HPK1,active,0.287,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cnn(CCOCCN)c3)ncc2c(N)n1,HPK1,active,0.668,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3[C@@H](C)[C@@H]3CC#N)ncc2c(N)n1,HPK1,active,0.763,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@@H](C)[C@H]3CC#N)ncc2c(N)n1,HPK1,active,0.837,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
C=Cc1c(-c2cnccc2C)nc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3CC#N)cc12,HPK1,active,0.225,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3cnn([C@@H](C)C#N)c3)ncc2c(N)n1,HPK1,active,0.297,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
CCc1c(-c2cnccc2C)nc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3CC#N)cc12,HPK1,active,0.139,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
CCc1c(-c2cnccc2C)nc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3CC#N)cc12,HPK1,active,0.768,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1nc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3CC#N)cc2c1Cl,HPK1,active,0.116,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccc(O)cc1-c1cc2cc(NC(=O)C3CC3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,0.147,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccc(F)cc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,0.113,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3cnn(C(C)(C)CO)c3)ncc2c(N)n1,HPK1,active,0.118,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3ccc(N4CCNCC4=O)cc3)ncc2c(N)n1,HPK1,active,0.249,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3ccc(CS(N)(=O)=O)cc3)ncc2c(N)n1,HPK1,active,0.134,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3cc(C)n(CCO)n3)ncc2c(N)n1,HPK1,active,0.439,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3cnn(CC(C)(C)O)c3)ncc2c(N)n1,HPK1,active,0.73,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1nc(N)c2cnc(NC(=O)C3CC3)cc2c1-c1cn[nH]c1,HPK1,active,0.695,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3cnn([C@H]4CCCN(C)C4=O)c3)ncc2c(N)n1,HPK1,active,0.569,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3cnn([C@@H]4CCCN(C)C4=O)c3)ncc2c(N)n1,HPK1,active,0.512,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3cnn([C@H]4CCN(C)C4=O)c3)ncc2c(N)n1,HPK1,active,0.184,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3cnn([C@@H]4CCN(C)C4=O)c3)ncc2c(N)n1,HPK1,active,0.433,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
N#C[C@@H]1C[C@H]1C(=O)Nc1cc2cc(-c3cnccc3-c3cn[nH]c3)nc(N)c2cn1,HPK1,active,0.706,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1nc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)cc2c1Cl,HPK1,active,0.694,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C3CNC(=O)O3)ncc2c(N)n1,HPK1,active,0.173,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)C3[C@@H]4CCC(C#N)[C@H]34)ncc2c(N)n1,HPK1,active,0.295,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Nc1nc(-c2cncc3c2OCCN3)cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc12,HPK1,active,0.135,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3cnn([C@H]4CCN(C5COC5)C[C@@H]4O)c3)ncc2c(N)n1,HPK1,active,0.592,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3cnn([C@H]4CN(C5COC5)CC[C@@H]4O)c3)ncc2c(N)n1,HPK1,active,0.567,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)C3CC3CC#N)ncc2c(N)n1,HPK1,active,0.685,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Nc1nc(-c2cncc3c2CCN3)cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc12,HPK1,active,0.154,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1nc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3CC#N)cc2c1Br,HPK1,active,0.258,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1nc(N)c2cnc(NC(=O)C3CC3)cc2c1C1=CC(O)CC1,HPK1,active,0.99,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3CC#N)ncc2c(N)n1,HPK1,active,0.967,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
N#CC[C@H]1C[C@@H]1C(=O)Nc1cc2cc(-c3cnccc3CCO)nc(N)c2cn1,HPK1,active,0.501,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3cnn(C(C)(C)C(=O)N(C)C)c3)ncc2c(N)n1,HPK1,active,0.98,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)Nc3cnn(C(C)C#N)c3)ncc2c(N)n1,HPK1,active,0.25,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3cnn(CCO)c3)ncc2c(N)n1,HPK1,active,0.48,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cnsc3)ncc2c(N)n1,HPK1,active,0.15,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)C3CC34CN(c3ncccc3C#N)C4)ncc2c(N)n1,HPK1,active,0.77,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@]34CCN(S(C)(=O)=O)C4)ncc2c(N)n1,HPK1,active,0.78,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1cc2[nH]c(=O)oc2cc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3C#N)ncc2c(N)n1,HPK1,active,0.25,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cccnc3)ncc2c(N)n1,HPK1,active,0.31,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
CCOc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C#N)ncc2c(N)n1,HPK1,active,0.98,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cc[nH]n3)ncc2c(N)n1,HPK1,active,0.58,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)C3CC3C)ncc2c(N)n1,HPK1,active,0.476,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
CCc1ccncc1-c1cc2cc(Nc3cccc(CO)n3)ncc2c(N)n1,HPK1,active,0.3,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
CCc1ccncc1-c1cc2cc(Nc3cc(C(O)CC)ccn3)ncc2c(N)n1,HPK1,active,0.4,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
CCc1ccncc1-c1cc2cc(Nc3cc(C(=O)N(C)CC)ccn3)ncc2c(N)n1,HPK1,active,0.3,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
CCc1ccncc1-c1cc2cc(Nc3cc(C)ncn3)ncc2c(N)n1,HPK1,active,0.3,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
CCc1ccncc1-c1cc2cc(Nc3cnn(C4CCNCC4)c3)ncc2c(N)n1,HPK1,active,0.1,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
CCc1ccncc1-c1cc2cc(Nc3cc[nH]n3)ncc2c(N)n1,HPK1,active,0.6,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
CCc1ccncc1-c1cc2cc(Nc3cn[nH]c3)ncc2c(N)n1,HPK1,active,0.8,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
CCc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3COC)ncc2c(N)n1,HPK1,active,0.736,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
CCc1ccncc1-c1cc2cc(NC(=O)C3CC3)ncc2c(N)n1,HPK1,active,0.21,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)C3CC3)ncc2c(N)n1,HPK1,active,0.68,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc2c(N)n1,HPK1,active,0.38,Ki,WO2018183956A1_Original_document_20201230132016,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)NC4CCOCC4)ncc3cc2F)cnc2c1NCCO2,HPK1,active,0.83,Ki,WO2020072627A1_Original_document_20201119122058,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)NCC4CC4)ncc3cc2F)cnc2c1NCCO2,HPK1,active,0.5,Ki,WO2020072627A1_Original_document_20201119122058,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N[C@@H]4CCOC4)ncc3cc2F)cnc2c1NCCO2,HPK1,active,0.88,Ki,WO2020072627A1_Original_document_20201119122058,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4[C@@H]5CNC[C@@H]54)ncc3cc2F)cnc2c1NCCO2,HPK1,active,0.58,Ki,WO2020072627A1_Original_document_20201119122058,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CCC[C@@H]4C#N)ncc3cc2F)cnc2c1NCCO2,HPK1,active,0.78,Ki,WO2020072627A1_Original_document_20201119122058,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CCC[C@H]4C#N)ncc3c(Cl)c2F)cnc2c1NCCO2,HPK1,active,0.805,Ki,WO2020072627A1_Original_document_20201119122058,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CCCC[C@H]4C#N)ncc3c(Cl)c2F)cnc2c1NCCO2,HPK1,active,0.945,Ki,WO2020072627A1_Original_document_20201119122058,Below 1 nM
CC[C@@H]1[C@@H](C(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)cc3cn2)[C@@H]1c1cnn(C)c1,HPK1,active,0.9,Ki,WO2020072627A1_Original_document_20201119122058,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N[C@H](C)c4cnn(C)c4)ncc3cc2F)cnc2c1NCCO2,HPK1,active,0.95,Ki,WO2020072627A1_Original_document_20201119122058,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)NC4CC4)ncc3cc2F)cnc2c1NCCO2,HPK1,active,0.2,Ki,WO2020072627A1_Original_document_20201119122058,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)NC4CNC4)ncc3cc2F)cnc2c1NCCO2,HPK1,active,0.76,Ki,WO2020072627A1_Original_document_20201119122058,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CC5(CCNC5)C4)ncc3cc2F)cnc2c1NCCO2,HPK1,active,0.47,Ki,WO2020072627A1_Original_document_20201119122058,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CC5(CNC5)C4)ncc3cc2F)cnc2c1NCCO2,HPK1,active,0.34,Ki,WO2020072627A1_Original_document_20201119122058,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OCCC4C5CNCC45)ncc3cc2F)cnc2c1NCCO2,HPK1,active,0.44,Ki,WO2020072627A1_Original_document_20201119122058,Below 1 nM
Cc1c(-c2cc3cc(NC(=O)OC4CC5(CCNCC5)C4)ncc3cc2F)cnc2c1NCCO2,HPK1,active,0.27,Ki,WO2020072627A1_Original_document_20201119122058,Below 1 nM
CNC(=O)N1CC(OC(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)cc3cn2)C1,HPK1,active,0.91,Ki,WO2020072627A1_Original_document_20201119122058,Below 1 nM
Cc1c(N)cncc1-c1cc(N)c2nnc(NC(=O)[C@@H]3C[C@H]3C#N)cc2c1,HPK1,active,0.7,Ki,WO2020069402A1_Original_document_20201120091428,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC5)ncc3c(C)n2)cnc2c1NCCO2,HPK1,active,0.66,Ki,WO2020023551A1_Original_document_20201120101107,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)Cc3nccn3CC4)ncc2c(C)n1,HPK1,active,0.85,Ki,WO2020023551A1_Original_document_20201120101107,Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C(C)C)CC5)ncc3cn2)cnc2c1NCCO2,HPK1,active,0.39,Ki,WO2020023551A1_Original_document_20201120101107,Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC43CC3)ncc2c(C)n1,HPK1,active,0.27,Ki,WO2020023551A1_Original_document_20201120101107,Below 1 nM
CCc1c(Cl)[nH]c2ncc(-c3ccc(N)c(C(=O)N(C)C)c3)cc12,HPK1,active,0.9,Ki,WO2018167147A1_Original_document_20201120072807,Below 1 nM
CNCc1cc(OC)cc2c1CN(c1cccc(N3C(=O)OC[C@@H]3C)n1)C2=O,HPK1,active,3,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CCn1cnnc1-c1cccc(N2Cc3c(CNC)cc(OC)cc3C2=O)n1,HPK1,active,3,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CNCc1cc(OC)cc2c1CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,2,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CNCc1nc(N(C)C)cc2c1CN(c1cccc(-c3nnc4n3[C@H](C)CC4)n1)C2=O,HPK1,active,2.11,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
CC[C@@H]1CCc2nnc(-c3cccc(N4Cc5c(cc(N(C)C)nc5CNC)C4=O)n3)n21,HPK1,active,2.68,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
CC[C@@H]1CCc2nnc(-c3cccc(N4Cc5c(cc(N(C)C(C)C)nc5CNC)C4=O)n3)n21,HPK1,active,1.29,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
CC[C@@H]1CCc2nnc(-c3cccc(N4Cc5c(cc(N6CCC[C@H]6C)nc5CNC)C4=O)n3)n21,HPK1,active,1.04,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
CCn1cnnc1-c1cccc(N2Cc3c(cc(N(C)C)nc3[C@@H](C)N)C2=O)n1,HPK1,active,1.25,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
CCn1cnnc1-c1cccc(N2Cc3c(cc(N(C)C)nc3[C@H](C)N)C2=O)n1,HPK1,active,1.53,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
CC[C@H](N)c1nc(N(C)C)cc2c1CN(c1cccc(-c3nncn3CC)n1)C2=O,HPK1,active,1,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
CC[C@@H](N)c1nc(N(C)C)cc2c1CN(c1cccc(-c3nncn3CC)n1)C2=O,HPK1,active,3.14,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(N(C)C)nc3[C@@H](N)CC)C2=O)n1,HPK1,active,3.73,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(N(C)C)nc3[C@H](N)CC)C2=O)n1,HPK1,active,1.54,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(N(C)C)nc3C(C)(C)N)C2=O)n1,HPK1,active,1.02,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
CCN(C)c1cc2c(c([C@H](C)N)n1)CN(c1cccc(-c3nnc(C)n3CC)n1)C2=O,HPK1,active,1.03,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
CCN(C)c1cc2c(c([C@@H](C)N)n1)CN(c1cccc(-c3nnc(C)n3CC)n1)C2=O,HPK1,active,1.41,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
CCC(CC)n1cnnc1-c1cccc(N2Cc3c(cc(C4(C)CC4)nc3[C@@H](C)N)C2=O)n1,HPK1,active,1.78,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
CCC(CC)n1cnnc1-c1cccc(N2Cc3c(cc(C4(C)CC4)nc3[C@H](C)N)C2=O)n1,HPK1,active,1.42,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(C4(C)CC4)nc3[C@H](N)CC)C2=O)n1,HPK1,active,4.12,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
CC[C@H](N)c1nc(C2(C)CC2)cc2c1CN(c1cccc(-c3nncn3CC)n1)C2=O,HPK1,active,2.97,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(C4(C)CC4)nc3[C@H](C)N)C2=O)n1,HPK1,active,1.5,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(C4(C)CC4)nc3[C@@H](C)N)C2=O)n1,HPK1,active,1.02,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
CCn1cnnc1-c1cccc(N2Cc3c(cc(C4(C)CC4)nc3[C@@H](C)NC)C2=O)n1,HPK1,active,3.42,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
CCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N4CCC[C@H]4C)nc3[C@@H](C)NC)C2=O)n1,HPK1,active,1.02,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
CC[C@@H](N)c1nc(C2(C)CC2)cc2c1CN(c1cccc(-c3nncn3C3CCC3)n1)C2=O,HPK1,active,2.01,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
C[C@H](N)c1nc(C2(C)CC2)cc2c1CN(c1cccc(-c3nncn3C3CCC3)n1)C2=O,HPK1,active,2.36,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
C[C@@H](N)c1nc(C2(C)CC2)cc2c1CN(c1cccc(-c3nncn3C3CCC3)n1)C2=O,HPK1,active,1.38,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
C[C@H]1CCc2nnc(-c3cccc(N4Cc5c(cc(N6CCC[C@H]6C)nc5[C@@H](C)N)C4=O)n3)n21,HPK1,active,1.76,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
C[C@@H]1CCc2nnc(-c3cccc(N4Cc5c(cc(N(C)C)nc5C(C)(C)N)C4=O)n3)n21,HPK1,active,5,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
CC[C@H](N)c1nc(N2CCC[C@H]2C)cc2c1CN(c1cccc(-c3nnc4n3[C@@H](CC)CC4)n1)C2=O,HPK1,active,8.47,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
CC[C@@H]1CCc2nnc(-c3cccc(N4Cc5c(cc(N(C)C(C)C)nc5[C@@H](C)N)C4=O)n3)n21,HPK1,active,1.98,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
CC[C@H](N)c1nc(N2CCC[C@H]2C)cc2c1CN(c1cccc(-c3nnc4n3[C@H](C)CC4)n1)C2=O,HPK1,active,9.72,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
CC[C@@H]1CCc2nnc(-c3cccc(N4Cc5c(cc(N6CCC[C@H]6C)nc5[C@H](C)N)C4=O)n3)n21,HPK1,active,5.6,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
CC[C@@H]1CCc2nnc(-c3cccc(N4Cc5c(cc(N6CCC[C@H]6C)nc5[C@@H](C)N)C4=O)n3)n21,HPK1,active,2.8,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
COC[C@H](N)c1nc(C2(C)CC2)cc2c1CN(c1cccc(-c3nnc4n3[C@@H](C)CC4)n1)C2=O,HPK1,active,6.1,Ki,WO2021220185A1（HPK1）,1 nM to 10 nM
Cc1ccncc1-c1c(Cl)c(N)c2cnc(NC(=O)[C@@H]3[C@H]4CC(O)C[C@H]43)cc2c1Cl,HPK1,active,2.27,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@H]4CC(O)C[C@H]43)ncc2c(N)c1Cl,HPK1,active,1.29,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccnc(-c2ccn(C)n2)c1-c1cc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)cc2c1,HPK1,active,3.26,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1cccc(C#N)c1-c1cc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3C#N)cc2c1,HPK1,active,3.26,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc2cc(Nc3cnn([C@@H](C)C#N)c3)ncc2c(N)c1Cl,HPK1,active,1.02,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc(N)c2cnc(Nc3ccn([C@H](C)C#N)n3)cc2c1,HPK1,active,1.17,Ki,WO2018183964A1(1),1 nM to 10 nM
C[C@@H]1Cc2c(cncc2-c2cc(N)c3ccc(NC(=O)C4CC4)cc3c2)N1,HPK1,active,1.05,Ki,US2018282282A1（HPK1）,1 nM to 10 nM
Cc1c(NC(C)C)cncc1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3C#N)cc2c1,HPK1,active,6.96,Ki,US2018282282A1（HPK1）,1 nM to 10 nM
N#C[C@H]1C[C@@H]1C(=O)NC1=CC2C=C(N3CCOC3=O)C=C(N)C2C=N1,HPK1,active,2.71,Ki,US2018282282A1（HPK1）,1 nM to 10 nM
CC(C)[C@@H]1COC(=O)N1c1cc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3C#N)cc2c1,HPK1,active,1.04,Ki,WO2018183964A1(1),1 nM to 10 nM
C[C@H]1COC(=O)N1c1cc2cc(NC(=O)[C@@H]3C[C@H]3C#N)ncc2c(N)c1F,HPK1,active,1.7,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3CC3CC#N)ncc2c(N)c1C(F)(F)F,HPK1,active,7,Ki,US2018282282A1（HPK1）,1 nM to 10 nM
N#C[C@H]1C[C@@H]1C(=O)Nc1ccc2c(N)cc(-c3cn[nH]c3)cc2c1,HPK1,active,5.5,Ki,US2018282282A1（HPK1）,1 nM to 10 nM
Cc1[nH]nc(CO)c1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3C#N)cc2c1,HPK1,active,2.8,Ki,US2018282282A1（HPK1）,1 nM to 10 nM
Cc1csnc1-c1cc(N)c2cnc(NC(=O)C3CC3C#N)cc2c1,HPK1,active,4.32,Ki,WO2018183964A1(1),1 nM to 10 nM
N#CC1CC1C(=O)Nc1cc2cc(-c3c[nH]nc3C(F)(F)F)cc(N)c2cn1,HPK1,active,3.16,Ki,WO2018183964A1(1),1 nM to 10 nM
C=C(Nc1cc2cc(-c3cnccc3CC)cc(N)c2cn1)[C@@H]1C[C@@H]1F,HPK1,active,1.04,Ki,US2018282282A1（HPK1）,1 nM to 10 nM
Cc1cnsc1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3C#N)cc2c1,HPK1,active,1.83,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1cnccc1-c1cc(N)c2cnc(NC(=O)[C@H]3C[C@H]3F)cc2c1,HPK1,active,8.4,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1c(-c2cc(N)c3cnc(NC(=O)[C@@H]4C[C@@H]4F)cc3c2)cnc2[nH]cnc12,HPK1,active,1.66,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)[C@H]3[C@@H](C)[C@@H]3c3cnn(C)c3)cc2c1,HPK1,active,3.76,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@@H](C)[C@H]3c3cnn(C)c3)ncc2c(N)c1F,HPK1,active,2.23,Ki,WO2018183964A1(1),1 nM to 10 nM
CNC(=O)Nc1cc2c(C#N)c(-c3cnccc3C)cc(N)c2cn1,HPK1,active,1.19,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3CO)cc2c1,HPK1,active,2.52,Ki,WO2018183964A1(1),1 nM to 10 nM
CCc1ccncc1-c1cc(N)c2cnc(NC(=O)[C@H]3C[C@H]3C#N)cc2c1,HPK1,active,1.6,Ki,WO2018183964A1(1),1 nM to 10 nM
CCc1cc(CO)ncc1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@@H]3F)cc2c1,HPK1,active,5.27,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc(N)c2cnc(Nc3ccn([C@@H](C)C#N)n3)cc2c1,HPK1,active,2.12,Ki,WO2018183964A1(1),1 nM to 10 nM
CNC(=O)Nc1cc2cc(-c3cnccc3C)c(C#N)c(N)c2cn1,HPK1,active,3.8,Ki,WO2018183964A1(1),1 nM to 10 nM
CC(C)c1c(-c2cc(N)c3cnc(NC(=O)[C@@H]4C[C@H]4C#N)cc3c2)cnn1C,HPK1,active,1.2,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1csnc1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3C#N)cc2c1,HPK1,active,2.8,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1c(F)c(N)c2cnc(NC(=O)[C@H]3C[C@@H]3C#N)cc2c1F,HPK1,active,5.8,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)C3CC3C#N)ncc2c(N)c1Cl,HPK1,active,2.53,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1c(-c2cc(N)c3cnc(NC(=O)[C@@H]4C[C@H]4C#N)cc3c2)cnc2nccnc12,HPK1,active,5.67,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1cc2[nH]c(=O)oc2cc1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3C#N)cc2c1,HPK1,active,2.53,Ki,WO2018183964A1(1),1 nM to 10 nM
COc1ccncc1-c1cc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3F)cc2c1,HPK1,active,2.51,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1c[nH]c(=O)cc1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@@H]3F)cc2c1,HPK1,active,5.41,Ki,WO2018183964A1(1),1 nM to 10 nM
Cn1cc(-c2cc3cc(NC(=O)C4CC4)ncc3c(N)c2C#N)cn1,HPK1,active,6.54,Ki,WO2018183964A1(1),1 nM to 10 nM
Cn1cc([C@H]2C[C@@H]2C(=O)Nc2cc3cc(-c4c(Cl)cccc4Cl)cc(N)c3cn2)cn1,HPK1,active,1.45,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3[C@@H](C)[C@@H]3c3cnn(C)c3)ncc2c(N)c1F,HPK1,active,4.6,Ki,WO2018183964A1(1),1 nM to 10 nM
C[C@H]1Cc2c(cncc2-c2cc(N)c3cnc(NC(=O)C4CC4)cc3c2)N1,HPK1,active,5.44,Ki,WO2018183964A1(1),1 nM to 10 nM
N#C[C@H]1C[C@@H]1C(=O)Nc1cc2cc(N3C(=O)OC4CCCC43)cc(N)c2cn1,HPK1,active,8.96,Ki,WO2018183964A1(1),1 nM to 10 nM
CNC(=O)Nc1cc2c(Cl)c(-c3cnccc3C)cc(N)c2cn1,HPK1,active,3.8,Ki,WO2018183964A1(1),1 nM to 10 nM
CNC(=O)Nc1cc2cc(-c3cnccc3C)c(Cl)c(N)c2cn1,HPK1,active,4.8,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C#N)ncc2c(N)c1Cl,HPK1,active,2.5,Ki,WO2018183964A1(1),1 nM to 10 nM
CNC(=O)Nc1cc2cc(-c3cnccc3C)c(F)c(N)c2cn1,HPK1,active,3.2,Ki,WO2018183964A1(1),1 nM to 10 nM
N#C[C@@H]1C[C@H]1C(=O)Nc1cc2cc(-c3c[nH]nc3C(F)(F)F)cc(N)c2cn1,HPK1,active,3.2,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1[nH]nc(CO)c1-c1cc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3C#N)cc2c1,HPK1,active,2.8,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1c(-c2cc(N)c3cnc(NC(=O)C4CC4C#N)cc3c2)cnc2nccnc12,HPK1,active,5.67,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1c(F)c(N)c2cnc(NC(=O)C3CC3C#N)cc2c1F,HPK1,active,5.81,Ki,WO2018183964A1(1),1 nM to 10 nM
Cn1cc2c(-c3cc(N)c4cnc(NC(=O)C5CC5C#N)cc4c3)cncc2n1,HPK1,active,8.82,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C3CC3CO)cc2c1,HPK1,active,1.03,Ki,WO2018183964A1(1),1 nM to 10 nM
N#CC1CC1C(=O)Nc1cc2cc(-c3cn[nH]c3)cc(N)c2cn1,HPK1,active,5.53,Ki,WO2018183964A1(1),1 nM to 10 nM
N#C[C@H]1C[C@@H]1C(=O)Nc1cc2cc(-c3cnccc3CCO)cc(N)c2cn1,HPK1,active,3.45,Ki,WO2018183964A1(1),1 nM to 10 nM
Nc1cc(-c2cccnc2)cc2cc(NC(=O)[C@H]3C[C@H]3F)ncc12,HPK1,active,6.71,Ki,WO2018183964A1(1),1 nM to 10 nM
COc1ccncc1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@@H]3F)cc2c1,HPK1,active,7.19,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3C#N)cc2c1,HPK1,active,1.2,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1[nH]ncc1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@@H]3F)cc2c1,HPK1,active,1.94,Ki,WO2018183964A1(1),1 nM to 10 nM
CCCn1c(CC)nnc1-c1cccc(N2Cc3c(cc(N4CCC[C@H]4C)nc3CN)C2=O)n1,HPK1,active,1.91,Ki,AU2019378184A1（HPK1）Ki,1 nM to 10 nM
CC[C@@H](CO)C1C=NN=C1c1cccc(N2Cc3c(cc(C4(C)CC4)nc3CNC)C2=O)n1,HPK1,active,1.15,Ki,AU2019378184A1（HPK1）Ki,1 nM to 10 nM
CCN(c1cc2c(c(CN)n1)CN(c1cccc(-c3nncs3)n1)C2=O)C(C)C,HPK1,active,2.07,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
CCn1c(C)nnc1-c1cccc(N2Cc3c(cc(C4(C)CC4)nc3CN)C2=O)n1,HPK1,active,1.52,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
C[C@@H]1CC[C@@H](C)N1c1cc2c(c(CN)n1)CN(c1cccc(N3C(=O)OC[C@@H]3CF)n1)C2=O,HPK1,active,1.5,Ki,AU2019378184A1（HPK1）Ki,1 nM to 10 nM
CCN(c1cc2c(c(CN)n1)CN(c1cccc(N3C(=O)OC[C@@H]3CF)n1)C2=O)C(C)C,HPK1,active,1.03,Ki,AU2019378184A1（HPK1）Ki,1 nM to 10 nM
CNCc1nc(N2[C@H](C)CC[C@H]2C)cc2c1CN(c1cccc(-c3nnc(C)n3C(C)C)n1)C2=O,HPK1,active,1.04,Ki,AU2019378184A1（HPK1）Ki,1 nM to 10 nM
CNCc1nc(N2C[C@H](C)O[C@H](C)C2)cc2c1CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,1.49,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
CCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N4[C@H](C)CC[C@H]4C)nc3CNC)C2=O)n1,HPK1,active,1.01,Ki,AU2019378184A1（HPK1）Ki,1 nM to 10 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(C4CCC4)nc3CNC)C2=O)n1,HPK1,active,1.15,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
CNCc1nc(C2CC2)cc2c1CN(c1cccc(N3C(=O)OC[C@@H]3CF)n1)C2=O,HPK1,active,1.44,Ki,AU2019378184A1（HPK1）Ki,1 nM to 10 nM
CC1(c2cc3c(c(CN)n2)CN(c2cccc(N4C(=O)OC[C@@H]4CF)n2)C3=O)CC1,HPK1,active,1.11,Ki,AU2019378184A1（HPK1）Ki,1 nM to 10 nM
CCc1nnc(-c2cccc(N3Cc4c(cc(N(C)C(C)C)nc4CNC)C3=O)n2)n1CC,HPK1,active,1.29,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
CC(C)c1cc2c(c(CN)n1)CN(c1cccc(N3C(=O)OC[C@@H]3C)n1)C2=O,HPK1,active,4.6,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
CNCc1nc(N(C)C)cc2c1CN(c1cccc(N3C(=O)OC[C@@H]3C(F)F)n1)C2=O,HPK1,active,1.5,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
CC[C@@H]1C[C@H](C)N1c1cc2c(c(CN)n1)CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,1.32,Ki,AU2019378184A1（HPK1）Ki,1 nM to 10 nM
CNCc1nc(C(C)(C)C)cc2c1CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,3.2,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
CNCc1nc(N2[C@H]3CC[C@@H]2CC3)cc2c1CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,1,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
CCn1cnnc1-c1cccc(N2Cc3c(cc(N(C)C)nc3CNC)C2=O)n1,HPK1,active,2.8,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
Cc1cnsc1-c1cc(N)c2cnc(NC(=O)C3CC3C#N)cc2c1,HPK1,active,1.67,Ki,WO2018183964A1(1),1 nM to 10 nM
C[C@@H]1Cc2c(cncc2-c2cc(N)c3cnc(NC(=O)C4CC4)cc3c2)N1,HPK1,active,1.05,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1c(NC(C)C)cncc1-c1cc(N)c2cnc(NC(=O)[C@@H]3CC3C#N)cc2c1,HPK1,active,6.96,Ki,WO2018183964A1(1),1 nM to 10 nM
N#C[C@H]1C[C@@H]1C(=O)Nc1cc2cc(N3CCOC3=O)cc(N)c2cn1,HPK1,active,2.71,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C#N)ncc2c(N)c1C(F)(F)F,HPK1,active,7,Ki,WO2018183964A1(1),1 nM to 10 nM
CCc1ccncc1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@@H]3F)cc2c1,HPK1,active,1.04,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1c(-c2cc(F)c3cnc(Nc4cc5n(n4)CC(=O)N(C)CC5)cc3c2)cnc2c1NCC[C@@]2(C)O,HPK1,active,1.3,Ki,WO2020023560A1,1 nM to 10 nM
CN[C@@H]1CCN(c2cc(C)c(-c3cc4cc(Nc5cc6n(n5)CC(=O)N(C)CC6)ncc4cc3F)cn2)C1,HPK1,active,6.7,Ki,WO2020023560A1,1 nM to 10 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CS(=O)(=O)N(C)C5)ncc3cc2F)cnc2c1NCC[C@H]2O,HPK1,active,1.7,Ki,WO2020023560A1,1 nM to 10 nM
CO[C@@H]1CCNc2c1ncc(-c1cc(F)c3cnc(Nc4cc5n(n4)CC(=O)N(C)CC5)cc3c1)c2C,HPK1,active,2.1,Ki,WO2020023560A1,1 nM to 10 nM
CN[C@H]1CCN(c2cc(C)c(-c3cc4cc(Nc5cc6n(n5)CC(=O)N(C)CC6)ncc4cc3F)cn2)C1,HPK1,active,6.2,Ki,WO2020023560A1,1 nM to 10 nM
[C-]#[N+][C@H](C)n1ccc(Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)cc3cn2)n1,HPK1,active,1.19,Ki,WO2020023560A1,1 nM to 10 nM
[C-]#[N+][C@@H](C)n1ccc(Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)cc3cn2)n1,HPK1,active,2.17,Ki,WO2020023560A1,1 nM to 10 nM
CNCc1cc(C)c(-c2ccc3cnc(Nc4cc5n(n4)CC(=O)N(C)CC5)cc3c2)c(F)c1,HPK1,active,5.2,Ki,WO2020023560A1,1 nM to 10 nM
CNCc1ccc(F)c(-c2ccc3cnc(Nc4cc5n(n4)CC(=O)N(C)CC5)cc3c2)c1C,HPK1,active,7,Ki,WO2020023560A1,1 nM to 10 nM
Cc1cc(C2CCCCO2)ncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC4)ncc2cc1F,HPK1,active,9,Ki,WO2020023560A1,1 nM to 10 nM
Cc1c(N)cnnc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC4)ncc2cc1F,HPK1,active,2.3,Ki,WO2020023560A1,1 nM to 10 nM
CN1CCc2cc(Nc3cc4cc(-c5cncc6c5CCC6O)c(F)cc4cn3)nn2CC1=O,HPK1,active,9,Ki,WO2020023560A1,1 nM to 10 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC5)ncc3cc2F)cnc2c(=O)n(C)[nH]c12,HPK1,active,1.9,Ki,WO2020023560A1,1 nM to 10 nM
CNC1CCN(c2cc(C)c(-c3cc4cc(Nc5cc6n(n5)CC(=O)N(C)CC6)ncc4cc3F)cn2)CC1,HPK1,active,5,Ki,WO2020023560A1,1 nM to 10 nM
Cc1cc(N2CCNCC2)ncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC4)ncc2cc1F,HPK1,active,4.2,Ki,WO2020023560A1,1 nM to 10 nM
Cc1c(NS(=O)(=O)C2CC2)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC4)ncc2cc1F,HPK1,active,4.1,Ki,WO2020023560A1,1 nM to 10 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CS(=O)CC4)ncc2cc1F,HPK1,active,2.6,Ki,WO2020023560A1,1 nM to 10 nM
CC(=O)Nc1cncc(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC5)ncc3cc2F)c1C,HPK1,active,1.78,Ki,WO2020023560A1,1 nM to 10 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C(C)C)CC5)ncc3cc2F)cnc2oc(=O)[nH]c12,HPK1,active,1.9,Ki,WO2020023560A1,1 nM to 10 nM
COc1cc(C)c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC5)ncc3cc2F)cn1,HPK1,active,2.2,Ki,WO2020023560A1,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(Nc3cc4n(n3)CC3=NOC(C)(C)N3CC4)ncc2cc1F,HPK1,active,3.4,Ki,WO2020023560A1,1 nM to 10 nM
Cc1ncc(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C(C)C)CC5)ncc3c(O)c2F)c(C)c1N,HPK1,active,3.7,Ki,WO2020023560A1,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)ncc2cc1F,HPK1,active,2.5,Ki,WO2020023560A1,1 nM to 10 nM
Cc1ccncc1-c1ccc2cnc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)cc2c1,HPK1,active,1,Ki,WO2020023560A1,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC4)ncc2c(Cl)c1F,HPK1,active,4.6,Ki,WO2020023560A1,1 nM to 10 nM
Cc1ccnc(Nc2cc3cc(-c4cnccc4C)ccc3cn2)c1,HPK1,active,4.4,Ki,WO2020023560A1,1 nM to 10 nM
Cc1cc(Nc2cc3cc(-c4cnccc4C)ccc3cn2)ncn1,HPK1,active,9,Ki,WO2020023560A1,1 nM to 10 nM
Cc1ccncc1-c1ccc2cnc(Nc3cc(C(F)F)ccn3)cc2c1,HPK1,active,6.6,Ki,WO2020023560A1,1 nM to 10 nM
CCc1ccnc(Nc2cc3cc(-c4cnccc4C)ccc3cn2)c1,HPK1,active,6,Ki,WO2020023560A1,1 nM to 10 nM
CCCn1c(CC)nnc1-c1cccc(N2Cc3c(cc(N4CCC[C@@H]4C)nc3CN)C2=O)n1,HPK1,active,1.91,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
C[C@H]1CC[C@H](C)N1c1cc2c(c(CN)n1)CN(c1cccc(N3C(=O)OC[C@H]3CF)n1)C2=O,HPK1,active,1.5,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
CCN(c1cc2c(c(CN)n1)CN(c1cccc(N3C(=O)OC[C@H]3CF)n1)C2=O)C(C)C,HPK1,active,1.03,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
CNCc1nc(N2[C@@H](C)CC[C@@H]2C)cc2c1CN(c1cccc(-c3nnc(C)n3C(C)C)n1)C2=O,HPK1,active,1.04,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
CCn1c(C)nnc1-c1cccc(N2Cc3c(cc(N4[C@@H](C)CC[C@@H]4C)nc3CNC)C2=O)n1,HPK1,active,1.01,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
CNCc1nc(C2CC2)cc2c1CN(c1cccc(N3C(=O)OC[C@H]3CF)n1)C2=O,HPK1,active,1.44,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
NCc1nc(C2CC2)cc2c1CN(c1cccc(N3C(=O)OC[C@H]3CF)n1)C2=O,HPK1,active,3.04,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
CC1(c2cc3c(c(CN)n2)CN(c2cccc(N4C(=O)OC[C@H]4CF)n2)C3=O)CC1,HPK1,active,1.11,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
CC[C@@H](CC(F)(F)F)n1cnnc1-c1cccc(N2Cc3c(cc(C(C)(C)C)nc3CNC)C2=O)n1,HPK1,active,7.1,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
CNCc1nc(C2(C)CC2)cc2c1CN(c1cccc(N3C(=O)OC[C@H]3C)n1)C2=O,HPK1,active,1.46,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
C[C@H]1C[C@H](C)N1c1cc2c(c(CN)n1)CN(c1cccc(N3C(=O)OC[C@H]3C)n1)C2=O,HPK1,active,1.92,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
CC(C)n1cnnc1-c1cccc(N2Cc3c(cc(N4[C@@H](C)C[C@H]4C)nc3CN)C2=O)n1,HPK1,active,1.32,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
CC[C@@H](CC(F)(F)F)n1cnnc1-c1cccc(N2Cc3c(cc(N(C)C)nc3CNC)C2=O)n1,HPK1,active,6.9,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
CCc1cnn(C2CCC3(CNc4ncc(-c5ccc(N)c(C(=O)N(C)C)c5F)c(Cl)c43)C2)c1,HPK1,active,5.54,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(CO)C2)CN3)c1F,HPK1,active,6.1,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
Cc1c(CC#N)ccnc1-c1cccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)c1F,HPK1,active,5.94,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
Cc1c(CC#N)ccnc1-c1cccc(-c2cnc3c(c2)C2(CC2)CN3)c1F,HPK1,active,3.15,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
Cc1c(CC#N)ccnc1-c1cccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)c1,HPK1,active,4.3,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(CO)CC2)CN3)c1F,HPK1,active,6.01,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
N#CC1CCCCN1C(=O)c1cccc(-c2cnc3c(c2)C2(CC2)CN3)c1F,HPK1,active,8.25,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
CC1CC12CNc1ncc(-c3ccc(N)c(C(=O)N(C)C)c3F)c(Cl)c12,HPK1,active,4.76,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CN3)CC2c2ccccc2)c1F,HPK1,active,3.58,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCCCC2)CN3)c1F,HPK1,active,4.76,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
CCCC1CC12CNc1ncc(-c3ccc(N)c(C(=O)N(C)C)c3F)c(Cl)c12,HPK1,active,5.13,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
CN(C)C(=O)c1cccc(-c2cnc3c(c2Cl)C2(CCC(C)(C(N)=O)C2)CN3)c1F,HPK1,active,6.23,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
CC(C)C1CC12CNc1ncc(-c3ccc(N)c(C(=O)N(C)C)c3F)c(Cl)c12,HPK1,active,3.64,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(Oc4ccccn4)C2)CN3)c1F,HPK1,active,6.75,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(n4cc(Cl)cn4)C2)CN3)c1F,HPK1,active,6.58,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
CN(Cc1cnn(C)c1)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CC2)CN3)c1F,HPK1,active,4.39,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
COc1c(-c2ccc(N)c(C(=O)N(C)C)c2F)cnc2c1C1(CN2)CC1C,HPK1,active,6.41,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(n4cc(C(F)(F)F)cn4)C2)CN3)c1F,HPK1,active,6.65,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
Cc1noc(C2(C)CCC3(CNc4ncc(-c5ccc(N)c(C(=O)N(C)C)c5F)c(Cl)c43)C2)n1,HPK1,active,2.63,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
CCC1(C(N)=O)CCC2(CNc3ncc(-c4ccc(N)c(C(=O)N(C)C)c4F)c(Cl)c32)C1,HPK1,active,7.16,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
CCC1(C#N)CCC2(CNc3ncc(-c4ccc(N)c(C(=O)N(C)C)c4F)c(Cl)c32)C1,HPK1,active,4.35,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
CCC1CC12CNc1ncc(-c3ccc(N)c(C(=O)N(C)C)c3F)c(Cl)c12,HPK1,active,3.3,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
Cc1cnn(C2CCC3(CC2)CNc2ncc(-c4ccc(N)c(C(=O)N(C)C)c4F)c(Cl)c23)c1,HPK1,active,2.21,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(CC#N)C2)CN3)c1F,HPK1,active,4,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
Cc1cnn(C2CCC3(CNc4ncc(-c5ccc(N)c(C(=O)N(C)C)c5F)c(Cl)c43)C2)c1,HPK1,active,3.56,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(n4ncnc4N)C2)CN3)c1F,HPK1,active,8.49,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
Cc1cnn(C2CCC3(CNc4ncc(-c5ccc(N)c(C(=O)N(C)C)c5F)c(Cl)c43)C2)n1,HPK1,active,2.84,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(C=C(c4cccnc4)CC2)CN3)c1F,HPK1,active,6.6,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
Cc1noc(C2CCC3(CNc4ncc(-c5ccc(N)c(C(=O)N(C)C)c5F)c(Cl)c43)C2)n1,HPK1,active,8.27,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(C(=O)O)C2)CN3)c1F,HPK1,active,9.85,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
CC1CC12CNc1ncc(-c3ccc(N)c(C(=O)N(C)C)c3F)cc12,HPK1,active,7.9,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(C)(O)C2)CN3)c1F,HPK1,active,8.12,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
Cn1cccc(-c2cccc(-c3cnc4c(c3Cl)C3(CC3)CN4)c2)c1=O,HPK1,active,9.06,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
CN(CCO)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC2)CN3)c1F,HPK1,active,4.4,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC2)CN3)c1F,HPK1,active,2.2,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
CN(CCO)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CC2)CN3)c1F,HPK1,active,4.7,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
Nc1cc(-c2cnc3c(c2Cl)C2(CC2)CN3)cc(-c2ncccc2CO)c1,HPK1,active,6.15,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)c1F,HPK1,active,6.95,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCCC2)CN3)c1F,HPK1,active,6.71,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CC2)CN3)c1F,HPK1,active,7.71,Ki,WO2020061377A1_Original_document_20201118034029,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4COC[C@H]4C)ncc3c(N)c2F)cnc2c1NC(=O)CO2,HPK1,active,3.75,Ki,WO2020072695A1,1 nM to 10 nM
Cc1c(N)cncc1-c1cc2cc(NC(=O)O[C@@H]3COC[C@H]3C)ncc2c(N)c1F,HPK1,active,2.7,Ki,WO2020072695A1,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4C[C@@H](O)C4)ncc3c(N)c2F)cnc2c1NC[C@H]1C[C@@H]21,HPK1,active,2.1,Ki,WO2020072695A1,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4Cc5nccn5C4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,5.76,Ki,WO2020072695A1,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H](C)CN(C)C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,8.75,Ki,WO2020072695A1,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)N(C)C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,1.12,Ki,WO2020072695A1,1 nM to 10 nM
CO[C@@H]1CCC[C@@H]1NC(=O)Nc1cc2cc(-c3cnc4c(c3C)NCCO4)c(F)c(N)c2cn1,HPK1,active,1.37,Ki,WO2020072695A1,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CCOC4)ncc3c(N)c2F)cnc2c1[C@@H](O)CC2,HPK1,active,1.7,Ki,WO2020072695A1,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)OC4CCOCC4)ncc3c(N)c2F)cnc2c1NCC[C@@H]2C,HPK1,active,1.01,Ki,WO2020072695A1,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)OC4C5CC4CN(C)C5)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,2.3,Ki,WO2020072695A1,1 nM to 10 nM
CN[C@H]1CCCC[C@@H]1OC(=O)Nc1cc2cc(-c3cnc4c(c3C)NCCO4)c(F)c(N)c2cn1,HPK1,active,3,Ki,WO2020072695A1,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3C(F)(F)F)ncc2c(N)n1,HPK1,active,1.4,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)N[C@H]3CCC[C@@H]3O)ncc2c(N)n1,HPK1,active,5.6,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1c(N)cccc1-c1cc2cc(NC(=O)[C@@H]3[C@H](C)[C@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,1,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
COC(=O)c1cc(C)c(-c2cc3cc(NC(=O)[C@@H]4C[C@H]4c4cnn(C)c4)ncc3c(N)n2)cn1,HPK1,active,7.6,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1cc(-n2cccn2)ncc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,3.6,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)N[C@H](C)CO)ncc2c(N)n1,HPK1,active,8.5,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
CCc1ccncc1-c1cc2cc(NC(=O)N[C@@H]3CCN(C)C3=O)ncc2c(N)n1,HPK1,active,5.5,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
CCc1ccncc1-c1cc2cc(Nc3cnn(CCO)c3)ncc2c(N)n1,HPK1,active,2,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
COCc1cccc(C)c1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,8,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1c(N)cccc1-c1cc2cc(NC(=O)[C@@H]3[C@@H](C)[C@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,8,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1c(N)cccc1-c1cc2cc(NC(=O)[C@H]3[C@@H](C)[C@@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,9.4,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccc2c(c1-c1cc3cc(NC(=O)[C@H]4C[C@@H]4CC#N)ncc3c(N)n1)CC[C@]2(C)O,HPK1,active,8,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
CC1=CN(C)C(=O)Cc2nc(Nc3cc4cc(-c5cnccc5C)nc(N)c4cn3)ccc21,HPK1,active,1.4,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1nc2c(=O)n(C)ncc2c(C)c1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,6.3,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)[C@H]4C[C@@H]4c4cnn(C)c4)ncc3c(N)n2)cnc2c(=O)n(C)ncc12,HPK1,active,9.9,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1nc2c(=O)n(C)ncc2cc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,6.3,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
COc1cc(C)c(-c2cc3cc(NC(=O)[C@@H]4C[C@H]4c4cnn(C)c4)ncc3c(N)n2)cn1,HPK1,active,5.6,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
COc1cncc(-c2cc3cc(NC(=O)[C@H]4C[C@@H]4c4cnn(C)c4)ncc3c(N)n2)c1C,HPK1,active,1.7,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1C#Cc1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,9.3,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
COCc1cc(C)c(-c2cc3cc(NC(=O)[C@@H]4C[C@H]4c4cnn(C)c4)ncc3c(N)n2)cn1,HPK1,active,1.6,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
COC(=O)[C@@H]1COC(c2cc(C)c(-c3cc4cc(NC(=O)[C@H]5C[C@@H]5c5cnn(C)c5)ncc4c(N)n3)cn2)=N1,HPK1,active,2.9,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1cc(C2=N[C@@H](C(C)C)CO2)ncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,1.8,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1cccc(CC#N)c1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,8.1,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccc(C#N)cc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3CC#N)ncc2c(N)n1,HPK1,active,1.8,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccccc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3CC#N)ncc2c(N)n1,HPK1,active,3.7,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cn1cc([C@H]2C[C@@H]2C(=O)Nc2cc3cc(-c4cc(C#N)ccc4Cl)nc(N)c3cn2)cn1,HPK1,active,1.4,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1c(N)cccc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3CC#N)ncc2c(N)n1,HPK1,active,7.3,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1c(N)ccc(Cl)c1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3CC#N)ncc2c(N)n1,HPK1,active,2.1,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1cccc(Cl)c1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3CC#N)ncc2c(N)n1,HPK1,active,2.3,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1cccc(F)c1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3CC#N)ncc2c(N)n1,HPK1,active,1.1,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1cccc(F)c1-c1cc2cc(NC(=O)[C@@H]3[C@@H](c4cnn(C)c4)[C@H]3C)ncc2c(N)n1,HPK1,active,2.7,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1cccc(F)c1-c1cc2cc(NC(=O)[C@H]3[C@@H](C)[C@@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,1.8,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1cc(C(N)=O)cc(F)c1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,5,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1cc(-c2ncco2)cc(F)c1-c1cc2cc(NC(=O)[C@@H]3[C@@H](c4cnn(C)c4)[C@H]3C)ncc2c(N)n1,HPK1,active,6.2,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1cc(C(=O)OCc2ccccc2)ncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,1.17,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
CNC(=O)c1cc(C)c(-c2cc3cc(NC(=O)[C@H]4C[C@@H]4c4cnn(C)c4)ncc3c(N)n2)cn1,HPK1,active,2.44,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1cc(-c2ccn(C)n2)ncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,2.26,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1cc(N2CCC2=O)ncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,1.73,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1cc(C(=O)O)ncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,1.43,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1cc(C(=O)N(C)C)ncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,6.14,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cn1cc([C@H]2C[C@@H]2C(=O)Nc2cc3cc(-c4cnc5c(=O)n(C)ncc5c4)nc(N)c3cn2)cn1,HPK1,active,3.14,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1cc(-c2ccccc2)ncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3CC#N)ncc2c(N)n1,HPK1,active,4.41,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cn1cc([C@H]2C[C@@H]2C(=O)Nc2cc3c(Cl)c(-c4cnccc4CCO)nc(N)c3cn2)cn1,HPK1,active,5.62,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
COCCn1cc([C@H]2C[C@@H]2C(=O)Nc2cc3cc(-c4cnccc4C)nc(N)c3cn2)cn1,HPK1,active,1.12,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3C3CCOCC3)ncc2c(N)n1,HPK1,active,3.43,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3CC[C@@H]3C)ncc2c(N)n1,HPK1,active,7.82,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@@]34CCNC(=O)C4)ncc2c(N)n1,HPK1,active,5.77,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
N#CC[C@@H]1C[C@H]1C(=O)Nc1cc2cc(-c3c(Cl)cccc3Cl)nc(N)c2cn1,HPK1,active,1.15,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1cc(-c2ncco2)ncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,3.04,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cn1cc([C@@H]2C[C@H]2C(=O)Nc2cc3cc(-c4c(F)cccc4F)nc(N)c3cn2)cn1,HPK1,active,3.25,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cn1cc([C@@H]2C[C@H]2C(=O)Nc2cc3cc(-c4ccccc4Cl)nc(N)c3cn2)cn1,HPK1,active,3.02,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccc(C#N)cc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,1.36,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
COC1CN(C2CC3C(C2)C3C(=O)Nc2cc3cc(-c4cnccc4C)nc(N)c3cn2)C1,HPK1,active,2.14,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccc(C(=O)N(C)C)cc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,3.36,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
COc1ccc(C)c(-c2cc3cc(NC(=O)[C@@H]4C[C@H]4c4cnn(C)c4)ncc3c(N)n2)c1,HPK1,active,7.39,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
COc1ccc(C)c(-c2cc3cc(NC(=O)[C@H]4C[C@@H]4c4cnn(C)c4)ncc3c(N)n2)c1,HPK1,active,6.19,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccc(O)cc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,1.82,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@@H](CC#N)[C@H]3C)ncc2c(N)n1,HPK1,active,6.01,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1nc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3CC#N)cc2c1Cl,HPK1,active,2.3,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(Nc3cnn(CC(F)F)c3)ncc2c(N)n1,HPK1,active,1.01,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Nc1nc(-c2cnccc2CCO)cc2cc(NC(=O)[C@H]3C[C@@H]3c3cccnc3)ncc12,HPK1,active,4.55,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1c(N)cncc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3CC#N)ncc2c(N)n1,HPK1,active,1.03,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Nc1nc(-c2cnccc2CCO)cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnsc3)ncc12,HPK1,active,5.42,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
N#C[C@H]1C[C@@H]1C(=O)Nc1cc2cc(-c3cnccc3-c3cc[nH]n3)nc(N)c2cn1,HPK1,active,3.56,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
N#C[C@@H]1C[C@H]1C(=O)Nc1cc2cc(-c3cnccc3-c3cc[nH]n3)nc(N)c2cn1,HPK1,active,1.37,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3C(C)(C)O)ncc2c(N)n1,HPK1,active,2.19,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
COC(C)(C)[C@@H]1C[C@H]1C(=O)Nc1cc2cc(-c3cnccc3C)nc(N)c2cn1,HPK1,active,5.28,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1cc(-c2cnn(C)c2)ncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3CC#N)ncc2c(N)n1,HPK1,active,1.94,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
CC(O)Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C#N)ncc2c(N)n1,HPK1,active,7.28,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Nc1nc(-c2cncc3c2OCC(=O)N3)cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc12,HPK1,active,1.77,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
CNc1cncc(-c2cc3cc(NC(=O)[C@@H]4C[C@@H]4F)ncc3c(N)n2)c1C,HPK1,active,3.53,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cn1cc([C@H]2C[C@@H]2C(=O)Nc2cc3cc(-c4cnccc4CCO)nc(N)c3cn2)cn1,HPK1,active,1.19,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(Nc3cnn(C(C)CO)c3)ncc2c(N)n1,HPK1,active,9.57,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
N#C[C@@H]1C[C@H]1C(=O)Nc1cc2cc(-c3cnccc3C(F)(F)F)nc(N)c2cn1,HPK1,active,6.49,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
N#C[C@H]1C[C@@H]1C(=O)Nc1cc2cc(-c3cnccc3CCO)nc(N)c2cn1,HPK1,active,2.7,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1c(N)cncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C(F)(F)F)ncc2c(N)n1,HPK1,active,1.1,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
C[C@H]1COC(=O)N1c1cc2cc(NC(=O)[C@@H]3C[C@H]3C#N)ncc2c(N)n1,HPK1,active,4,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
CNC(=O)Cn1cc(Nc2cc3cc(-c4cnccc4C)nc(N)c3cn2)cn1,HPK1,active,2.5,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
CNC(=O)C(C)(C)n1cc(Nc2cc3cc(-c4cnccc4C)nc(N)c3cn2)cn1,HPK1,active,1.2,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ncc(N)c(C)c1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3C)ncc2c(N)n1,HPK1,active,3.2,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1cc(N2CC[C@H](N)C2)ncc1-c1cc2cc(NC(=O)[C@H]3C[C@H]3F)ncc2c(N)n1,HPK1,active,2.9,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)NC3CNC3)ncc2c(N)n1,HPK1,active,3.4,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
COCCN1CC(NC(=O)Nc2cc3cc(-c4cnccc4C)nc(N)c3cn2)C1,HPK1,active,2.5,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(Nc3ccn(C)c(=O)c3)ncc2c(N)n1,HPK1,active,3,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1cc(-c2ccc[nH]c2=O)ncc1-c1cc2cc(NC(=O)[C@H]3C[C@H]3F)ncc2c(N)n1,HPK1,active,9.4,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
CC(=O)N1CCC([C@@H]2C[C@H]2C(=O)Nc2cc3cc(-c4cnccc4C)nc(N)c3cn2)CC1,HPK1,active,1.5,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1cc(C(=O)NCC(F)(F)F)ccc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3C#N)ncc2c(N)n1,HPK1,active,8.1,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1nc(N)c2cnc(NC(=O)Nc3cnn(C)c3)cc2c1Cl,HPK1,active,1.2,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1nc(N)c2cnc(NC(=O)Nc3cnn(C)c3)cc2c1F,HPK1,active,3.2,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1cc2c(cc1-c1cc3cc(NC(=O)[C@H]4C[C@@H]4C#N)ncc3c(N)n1)C(O)C(=O)N2,HPK1,active,1.2,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@H]4C(=O)NC[C@H]43)ncc2c(N)n1,HPK1,active,3.6,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3CN)ncc2c(N)n1,HPK1,active,2.4,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3CO)ncc2c(N)n1,HPK1,active,1.1,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1nc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3C#N)cc2c1F,HPK1,active,4.4,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@]34CCN(S(C)(=O)=O)C4)ncc2c(N)n1,HPK1,active,2.8,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
COc1ccc(Cn2cncc2[C@@H]2C[C@H]2C(=O)Nc2cc3cc(-c4cnccc4C)nc(N)c3cn2)cc1,HPK1,active,2,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1cc2[nH]c(=O)oc2cc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cn[nH]c3)ncc2c(N)n1,HPK1,active,1.1,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
CC(=O)N1C[C@@H]2C(C(=O)Nc3cc4cc(-c5cnccc5C)nc(N)c4cn3)[C@@H]2C1,HPK1,active,5.9,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1cc2c(cc1-c1cc3cc(NC(=O)[C@H]4C[C@@H]4C#N)ncc3c(N)n1)oc(=O)n2C,HPK1,active,1.4,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@@H]3C)ncc2c(N)n1,HPK1,active,2.3,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
N#C[C@H]1C[C@@H]1C(=O)Nc1cc2cc(-c3cn[nH]c3C(F)(F)F)nc(N)c2cn1,HPK1,active,6.5,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
CNC(=O)Nc1cc2cc(-c3cnccc3C)nc(N)c2cn1,HPK1,active,2.6,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
COCCN1CC[C@]2(C[C@@H]2C(=O)Nc2cc3cc(-c4cnccc4C)nc(N)c3cn2)C1,HPK1,active,2.5,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
COCCN1CC[C@]2(C[C@H]2C(=O)Nc2cc3cc(-c4cnccc4C)nc(N)c3cn2)C1,HPK1,active,5.3,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@]34CCNC4)ncc2c(N)n1,HPK1,active,7,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@]34CCNC4)ncc2c(N)n1,HPK1,active,6.8,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
COCCN1C[C@@H]2C(C(=O)Nc3cc4cc(-c5cnccc5C)nc(N)c4cn3)[C@@H]2C1,HPK1,active,1.1,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)C3[C@H]4COC[C@@H]34)ncc2c(N)n1,HPK1,active,4.9,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)C3CC3C(F)(F)F)ncc2c(N)n1,HPK1,active,1.42,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)NC(C)CO)ncc2c(N)n1,HPK1,active,8.47,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)C3C4COCC43)ncc2c(N)n1,HPK1,active,4.89,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
CC(C)c1[nH]ncc1-c1cc2cc(NC(=O)C3CC3C#N)ncc2c(N)n1,HPK1,active,2.24,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)C3CC34CNC4)ncc2c(N)n1,HPK1,active,3.53,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
N#CC1CC1C(=O)Nc1cc2cc(-c3cn[nH]c3)nc(N)c2cn1,HPK1,active,1.87,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)C3C4CNCC43)ncc2c(N)n1,HPK1,active,2.38,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
N#CC1CC1C(=O)Nc1cc2cc(-c3cnccc3C(F)(F)F)nc(N)c2cn1,HPK1,active,6.49,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
CCc1ccncc1-c1cc2cc(NC(=O)N[C@H]3C[C@@H](O)C3)ncc2c(N)n1,HPK1,active,1.3,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Nc1nc(-c2cccnc2)cc2cc(NC(=O)C3CC3F)ncc12,HPK1,active,4.97,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1n[nH]c(C)c1-c1cc2cc(NC(=O)C3CC3F)ncc2c(N)n1,HPK1,active,3.82,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
CCc1cc(OC)ncc1-c1cc2cc(NC(=O)C3CC3F)ncc2c(N)n1,HPK1,active,4.88,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
CCc1ccncc1-c1cc2cc(NC(=O)c3cnn(C4CCNCC4)c3)ncc2c(N)n1,HPK1,active,1.8,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
CCc1ccncc1-c1cc2cc(Nc3ccn(C)n3)ncc2c(N)n1,HPK1,active,1.3,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
CCc1ccncc1-c1cc2cc(Nc3cnn(C)c3)ncc2c(N)n1,HPK1,active,1.3,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
CCc1cc(N)ncc1-c1cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc2c(N)n1,HPK1,active,5.76,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
CCc1cc(OC)ncc1-c1cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc2c(N)n1,HPK1,active,4.88,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccnc(C)c1-c1cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc2c(N)n1,HPK1,active,5.03,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1cc2c(cc1-c1cc3cc(NC(=O)[C@@H]4C[C@@H]4F)ncc3c(N)n1)CC(=O)N2,HPK1,active,2.81,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
CCc1ccncc1-c1cc2cc(NC(=O)OCc3ccccc3)ncc2c(N)n1,HPK1,active,5.24,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1c[nH]c(=O)cc1-c1cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc2c(N)n1,HPK1,active,6.5,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
COc1cc(-c2cc3cc(NC(=O)[C@@H]4C[C@@H]4F)ncc3c(N)n2)c(C)cn1,HPK1,active,6.4,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)[C@@H]4C[C@@H]4F)ncc3c(N)n2)cnc2nc[nH]c12,HPK1,active,2.98,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3F)ncc2c(N)n1,HPK1,active,1.3,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
CC(C)c1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C#N)ncc2c(N)n1,HPK1,active,5.9,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
CNC(=O)c1ccc(-c2cc3cc(NC(=O)[C@@H]4C[C@@H]4F)ncc3c(N)n2)c(C)c1,HPK1,active,6.82,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
CC1CC1C(=O)Nc1cc2cc(-c3cnn(C)c3)nc(N)c2cn1,HPK1,active,1.85,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Nc1nc(-c2cnccc2C2CC2)cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc12,HPK1,active,1.52,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
CCc1ccncc1-c1cc2cc(NC(=O)NC(C)C)ncc2c(N)n1,HPK1,active,3.9,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
CCc1ccncc1-c1cc2cc(NC(=O)NCc3cncs3)ncc2c(N)n1,HPK1,active,1.75,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cn1cc(-c2cc3cc(NC(=O)C4CC4)ncc3c(N)n2)cn1,HPK1,active,1.08,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1cc(CO)ncc1-c1cc2cc(NC(=O)C3CC3)ncc2c(N)n1,HPK1,active,1.54,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1cnccc1-c1cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc2c(N)n1,HPK1,active,4.91,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
N#C[C@@H]1C[C@@H]1C(=O)Nc1cc2cc(-c3cncc4[nH]ccc34)nc(N)c2cn1,HPK1,active,2.76,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
CCc1ccncc1-c1cc2cc(NC(=O)C3CCC3)ncc2c(N)n1,HPK1,active,3.22,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1cc2[nH]cnc2cc1-c1cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc2c(N)n1,HPK1,active,7.9,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1cc(N)ncc1-c1cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc2c(N)n1,HPK1,active,7.21,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Nc1nc(-c2cnccc2C(F)F)cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc12,HPK1,active,9.46,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)C3CC3(F)F)ncc2c(N)n1,HPK1,active,3.65,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
COc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc2c(N)n1,HPK1,active,1.73,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
CNC(=O)Nc1cc2cc(-c3cnn(C)c3)nc(N)c2cn1,HPK1,active,7.16,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cn1cc(-c2cc3cc(NC(=O)[C@H]4C[C@@H]4F)ncc3c(N)n2)cn1,HPK1,active,1.64,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
CCc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C#N)ncc2c(N)n1,HPK1,active,1.31,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cn1cc(-c2cc3cc(NC(=O)[C@@H]4C[C@@H]4F)ncc3c(N)n2)cn1,HPK1,active,2.87,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1nn(C)c(C)c1-c1cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc2c(N)n1,HPK1,active,5.14,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)[C@@H]4C[C@@H]4F)ncc3c(N)n2)cnn1C,HPK1,active,1.56,Ki,WO2018183956A1_Original_document_20201230132016,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)OC4CCOCC4)ncc3cc2F)cnc2c1NCCO2,HPK1,active,5,Ki,WO2020072627A1_Original_document_20201119122058,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)OCC4CC4)ncc3cc2F)cnc2c1NCCO2,HPK1,active,2.7,Ki,WO2020072627A1_Original_document_20201119122058,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)N[C@H]4CCOC4)ncc3cc2F)cnc2c1NCCO2,HPK1,active,2.5,Ki,WO2020072627A1_Original_document_20201119122058,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CCC[C@H]4C#N)ncc3cc2F)cnc2c1NCCO2,HPK1,active,2.5,Ki,WO2020072627A1_Original_document_20201119122058,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CCC[C@@H]4C#N)ncc3c(Cl)c2F)cnc2c1NCCO2,HPK1,active,3.75,Ki,WO2020072627A1_Original_document_20201119122058,1 nM to 10 nM
CC[C@H]1[C@@H](C(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)cc3cn2)[C@@H]1c1cnn(C)c1,HPK1,active,1.8,Ki,WO2020072627A1_Original_document_20201119122058,1 nM to 10 nM
CC[C@H]1[C@H](C(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)cc3cn2)[C@H]1c1cnn(C)c1,HPK1,active,8,Ki,WO2020072627A1_Original_document_20201119122058,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)N[C@H](C)CC#N)ncc3cc2F)cnc2c1NCCO2,HPK1,active,4,Ki,WO2020072627A1_Original_document_20201119122058,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)N[C@@H](C)CC#N)ncc3cc2F)cnc2c1NCCO2,HPK1,active,1.1,Ki,WO2020072627A1_Original_document_20201119122058,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)OC4CC5(CCN(C)CC5)C4)ncc3cc2F)cnc2c1NCCC2,HPK1,active,1.07,Ki,WO2020072627A1_Original_document_20201119122058,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)OC4CC5(C4)CN(C)C5)ncc3cc2F)cnc2c1NCCC2,HPK1,active,1.15,Ki,WO2020072627A1_Original_document_20201119122058,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)OC4CS(=O)(=O)C4)ncc3cc2F)cnc2c1NCCO2,HPK1,active,4.1,Ki,WO2020072627A1_Original_document_20201119122058,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)OC4CCC45CCNC5)ncc3cc2F)cnc2c1NCCO2,HPK1,active,7.5,Ki,WO2020072627A1_Original_document_20201119122058,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)OC4CC5CC4CN5)ncc3cc2F)cnc2c1NCCO2,HPK1,active,8.7,Ki,WO2020072627A1_Original_document_20201119122058,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)OCC(C)(C)C)ncc3cc2F)cnc2c1NCCO2,HPK1,active,4.3,Ki,WO2020072627A1_Original_document_20201119122058,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)OCCc4ccccn4)ncc3cc2F)cnc2c1NCCO2,HPK1,active,9.5,Ki,WO2020072627A1_Original_document_20201119122058,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)OCCS(C)(=O)=O)ncc3cc2F)cnc2c1NCCO2,HPK1,active,6.2,Ki,WO2020072627A1_Original_document_20201119122058,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)OCC4CCCCO4)ncc3cc2F)cnc2c1NCCO2,HPK1,active,7.5,Ki,WO2020072627A1_Original_document_20201119122058,1 nM to 10 nM
COC(C)CCOC(=O)Nc1cc2cc(-c3cnc4c(c3C)NCCO4)c(F)cc2cn1,HPK1,active,1.5,Ki,WO2020072627A1_Original_document_20201119122058,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)OCC4(F)CCNCC4)ncc3cc2F)cnc2c1NCCO2,HPK1,active,4,Ki,WO2020072627A1_Original_document_20201119122058,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)OC4COC5(CCNC5)C4)ncc3cc2F)cnc2c1NCCO2,HPK1,active,4,Ki,WO2020072627A1_Original_document_20201119122058,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)OCC4CCNC4)ncc3cc2F)cnc2c1NCCO2,HPK1,active,2.1,Ki,WO2020072627A1_Original_document_20201119122058,1 nM to 10 nM
Cc1c(-c2cc3cc(NC(=O)OCC4(F)CCNC4)ncc3cc2F)cnc2c1NCCO2,HPK1,active,2.4,Ki,WO2020072627A1_Original_document_20201119122058,1 nM to 10 nM
CC(=O)N1CC(OC(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)cc3cn2)C1,HPK1,active,2.9,Ki,WO2020072627A1_Original_document_20201119122058,1 nM to 10 nM
Cc1c(N)cncc1-c1cc(N)c2nnc(NC(=O)[C@H]3C[C@@H]3C#N)cc2c1,HPK1,active,4,Ki,WO2020069402A1_Original_document_20201120091428,1 nM to 10 nM
CCc1ccncc1-c1cc(N)c2nnc(NC(=O)C3CC3F)cc2c1,HPK1,active,4,Ki,WO2020069402A1_Original_document_20201120091428,1 nM to 10 nM
Cc1cnsc1-c1cc(N)c2nnc(NC(=O)C3CC3F)cc2c1,HPK1,active,3,Ki,WO2020069402A1_Original_document_20201120091428,1 nM to 10 nM
CCc1ccncc1-c1cc(N)c2nnc(NC(=O)NC(C)C)cc2c1,HPK1,active,8,Ki,WO2020069402A1_Original_document_20201120091428,1 nM to 10 nM
Cc1cc(Nc2cc3cc(-c4cnccc4C)ncc3cn2)nc(N)n1,HPK1,active,3.9,Ki,WO2020023551A1_Original_document_20201120101107,1 nM to 10 nM
COc1nc(-c2cnc3c(c2C)NCCO3)cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC4)ncc12,HPK1,active,2.1,Ki,WO2020023551A1_Original_document_20201120101107,1 nM to 10 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)ncc2c(C)n1,HPK1,active,2.5,Ki,WO2020023551A1_Original_document_20201120101107,1 nM to 10 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)ncc2cn1,HPK1,active,2.3,Ki,WO2020023551A1_Original_document_20201120101107,1 nM to 10 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(CC(F)F)CC4)ncc2cn1,HPK1,active,4,Ki,WO2020023551A1_Original_document_20201120101107,1 nM to 10 nM
CCc1c(Cl)[nH]c2ncc(-c3ccc(N)c(C(=O)N(C)C)c3F)cc12,HPK1,active,2.7,Ki,WO2018167147A1_Original_document_20201120072807,1 nM to 10 nM
CN(C)C(=O)c1cc(-c2cnc3[nH]c(Cl)c(CCO)c3c2Cl)ccc1N,HPK1,active,9.4,Ki,WO2018167147A1_Original_document_20201120072807,1 nM to 10 nM
CCc1c(F)[nH]c2ncc(-c3ccc(N)c(C(=O)N(C)C)c3F)cc12,HPK1,active,1,Ki,WO2018167147A1_Original_document_20201120072807,1 nM to 10 nM
CCc1c(F)[nH]c2ncc(-c3cccc(N4CCOCC4=O)c3)cc12,HPK1,active,4,Ki,WO2018167147A1_Original_document_20201120072807,1 nM to 10 nM
CCc1c(Cl)[nH]c2ncc(-c3cccc(N4CCOCC4=O)n3)cc12,HPK1,active,2,Ki,WO2018167147A1_Original_document_20201120072807,1 nM to 10 nM
C=C(c1nc(-c2cnc3[nH]c(Cl)c(CC)c3c2)ccc1N)N(C)C,HPK1,active,3,Ki,WO2018167147A1_Original_document_20201120072807,1 nM to 10 nM
CCc1c(Cl)[nH]c2ncc(-c3cccc(N4CCOCC4=O)c3)cc12,HPK1,active,2,Ki,WO2018167147A1_Original_document_20201120072807,1 nM to 10 nM
CC(C)n1cnnc1-c1cccc(N2Cc3c(CNC[C@@H]4CCCO4)cccc3C2=O)n1,HPK1,active,30,Ki,WO2021224818A1（HPK1）,10 nM to 100 nM
CC[C@H](N)c1nc(C2(C)CC2)cc2c1CN(c1cccc(-c3nncn3C3CCC3)n1)C2=O,HPK1,active,10.5,Ki,WO2021220185A1（HPK1）,10 nM to 100 nM
Cc1ccnc(-c2cnn(C)c2)c1-c1cc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3CC#N)cc2c1,HPK1,active,49.7,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1ccnc(-c2ccnn2C)c1C1C=c2cc(NC(=O)[C@@H]3C[C@H]3c3cnn(C)c3)ncc2=C(N)C1,HPK1,active,57.1,Ki,US2018282282A1（HPK1）,10 nM to 100 nM
Cc1ccnc(-c2ccnn2C)c1-c1cc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)cc2c1,HPK1,active,16.1,Ki,US2018282282A1（HPK1）,10 nM to 100 nM
CN(C)S(=O)(=O)c1cc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3C#N)cc2c1,HPK1,active,10.1,Ki,WO2018183964A1(1),10 nM to 100 nM
CN(C)S(=O)(=O)c1cc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3C(N)=O)cc2c1,HPK1,active,68.5,Ki,WO2018183964A1(1),10 nM to 100 nM
CC1(C)CN(c2cc(N)c3cnc(NC(=O)[C@H]4C[C@@H]4C#N)cc3c2)C(=O)O1,HPK1,active,14.8,Ki,WO2018183964A1(1),10 nM to 100 nM
Cn1ncc2c(-c3cc(N)c4cnc(NC(=O)[C@H]5C[C@@H]5C#N)cc4c3)cccc21,HPK1,active,47.2,Ki,US2018282282A1（HPK1）,10 nM to 100 nM
Cc1coc(=O)n1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3C#N)cc2c1,HPK1,active,14,Ki,US2018282282A1（HPK1）,10 nM to 100 nM
Cc1cc(C(=O)NCC(F)(F)F)ccc1-c1cc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3C#N)cc2c1,HPK1,active,19,Ki,WO2018183964A1(1),10 nM to 100 nM
C#C[C@H]1C[C@@H]1C(=O)Nc1cc2cc(C3CNC(=O)O3)cc(N)c2cn1,HPK1,active,34,Ki,US2018282282A1（HPK1）,10 nM to 100 nM
CC1CNC(=O)N1c1cc(N)c2cnc(NC(=O)C3C[C@H]3C#N)cc2c1,HPK1,active,13,Ki,US2018282282A1（HPK1）,10 nM to 100 nM
CNC(=O)c1cc(-c2cc(N)c3cnc(NC(=O)[C@@H]4C[C@H]4C#N)cc3c2)n(C)n1,HPK1,active,24,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1cn2ccnc2cc1-c1cc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3C#N)cc2c1,HPK1,active,46,Ki,US2018282282A1（HPK1）,10 nM to 100 nM
CC1COC(=O)N1c1cc(N)c2cnc(NC(=O)C3CC3C#N)cc2c1,HPK1,active,13.7,Ki,WO2018183964A1(1),10 nM to 100 nM
CNC(=O)c1ccc(C)c(-c2cc(N)c3cnc(NC(=O)C4CC4C#N)cc3c2)c1,HPK1,active,45.3,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1cc(C(=O)NCC(F)(F)F)ccc1-c1cc(N)c2cnc(NC(=O)C3CC3C#N)cc2c1,HPK1,active,19,Ki,WO2018183964A1(1),10 nM to 100 nM
CN(C)c1ccncc1-c1cc(N)c2cnc(NC(=O)C3CC3C#N)cc2c1,HPK1,active,43.9,Ki,WO2018183964A1(1),10 nM to 100 nM
CCc1ccncc1-c1cc(N)c2cnc(NC(=O)Cc3ccn[nH]3)cc2c1,HPK1,active,12.9,Ki,WO2018183964A1(1),10 nM to 100 nM
Cn1ccc2c(-c3cc(N)c4cnc(NC(=O)C5CC5C#N)cc4c3)cncc21,HPK1,active,23.2,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1ncc(-c2cc(N)c3cnc(NC(=O)[C@H]4C[C@@H]4C#N)cc3c2)n1C,HPK1,active,33.8,Ki,WO2018183964A1(1),10 nM to 100 nM
CCC1CCC(=O)N1c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@@H]3F)cc2c1,HPK1,active,43.5,Ki,WO2018183964A1(1),10 nM to 100 nM
Nc1cc(C2CNC(=O)C2)cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc12,HPK1,active,75.7,Ki,WO2018183964A1(1),10 nM to 100 nM
N#C[C@H]1C[C@@H]1C(=O)Nc1cc2cc(-c3ccnc4[nH]ccc34)cc(N)c2cn1,HPK1,active,24,Ki,WO2018183964A1(1),10 nM to 100 nM
CC(C)NC(=O)Nc1cc2cc(-c3cnn(C)c3)cc(N)c2cn1,HPK1,active,27,Ki,WO2018183964A1(1),10 nM to 100 nM
CCn1cc(C)c(-c2cc(N)c3cnc(NC(=O)[C@@H]4C[C@@H]4C)cc3c2)cc1=O,HPK1,active,27.3,Ki,US2018282282A1（HPK1）,10 nM to 100 nM
Cc1cc2[nH]cnc2cc1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@@H]3F)cc2c1,HPK1,active,12,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1cc(C#N)ccc1-c1cc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3C#N)cc2c1,HPK1,active,57.5,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1cccc(C#N)c1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3C#N)cc2c1,HPK1,active,23.8,Ki,WO2018183964A1(1),10 nM to 100 nM
C[C@@H]1COC(=O)N1c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3F)cc2c1,HPK1,active,14.8,Ki,WO2018183964A1(1),10 nM to 100 nM
C[C@@H]1COC(=O)N1c1cc2cc(NC(=O)[C@@H]3C[C@H]3C#N)ncc2c(N)c1F,HPK1,active,86,Ki,WO2018183964A1(1),10 nM to 100 nM
C[C@@H]1COC(=O)N1c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3C#N)cc2c1,HPK1,active,14,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)CCN)cc2c1,HPK1,active,21.9,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1ccnc(N2CCCCC2)c1-c1cc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)cc2c1,HPK1,active,25.6,Ki,WO2018183964A1(1),10 nM to 100 nM
CNC(=O)c1ccc(C)c(-c2cc(N)c3cnc(NC(=O)[C@H]4C[C@@H]4C#N)cc3c2)c1,HPK1,active,45,Ki,WO2018183964A1(1),10 nM to 100 nM
CNC(=O)c1cc(-c2cc(N)c3cnc(NC(=O)C4CC4C#N)cc3c2)n(C)n1,HPK1,active,24.1,Ki,WO2018183964A1(1),10 nM to 100 nM
Cn1ncc2c(-c3cc(N)c4cnc(NC(=O)C5CC5C#N)cc4c3)cncc21,HPK1,active,47.2,Ki,WO2018183964A1(1),10 nM to 100 nM
N#CC1CC1C(=O)Nc1cc2cc(-c3cnccc3CCO)cc(N)c2cn1,HPK1,active,11.8,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)CC3COCCN3)cc2c1,HPK1,active,83.7,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1c(F)cncc1-c1cc(N)c2cnc(NC(=O)[C@H]3C[C@H]3F)cc2c1,HPK1,active,14.6,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1[nH]c(=O)ccc1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@@H]3F)cc2c1,HPK1,active,86.4,Ki,WO2018183964A1(1),10 nM to 100 nM
CCc1ccc(=O)n(C)c1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3C#N)cc2c1,HPK1,active,83,Ki,WO2018183964A1(1),10 nM to 100 nM
N#Cc1ccc2cc(NC(=O)C3CC3)ncc2c1N,HPK1,active,19.6,Ki,WO2018183964A1(1),10 nM to 100 nM
Nc1c(Cl)ccc2cc(NC(=O)C3CC3)ncc12,HPK1,active,92.5,Ki,WO2018183964A1(1),10 nM to 100 nM
Cn1cc([C@@H]2C[C@H]2C(=O)Nc2cc3cc(-c4c(F)cccc4F)cc(N)c3cn2)cn1,HPK1,active,18.5,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1ccnc(-c2cnn(C)c2)c1-c1cc(N)c2cnc(NC(=O)[C@H]3CC3Cc3cnn(C)c3)cc2c1,HPK1,active,23.5,Ki,US2018282282A1（HPK1）,10 nM to 100 nM
Cn1cc([C@@H]2C[C@H]2C(=O)Nc2cc3cc(-c4c(Cl)cccc4Cl)cc(N)c3cn2)cn1,HPK1,active,11.8,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1ccnc(N2CCCC2)c1-c1cc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)cc2c1,HPK1,active,81.5,Ki,WO2018183964A1(1),10 nM to 100 nM
Cn1cc2c(-c3cc(N)c4cnc(NC(=O)[C@H]5C[C@@H]5C#N)cc4c3)cncc2n1,HPK1,active,10.2,Ki,WO2018183964A1(1),10 nM to 100 nM
Cn1ccc2c(-c3cc(N)c4cnc(NC(=O)[C@H]5C[C@@H]5C#N)cc4c3)cncc21,HPK1,active,23,Ki,WO2018183964A1(1),10 nM to 100 nM
C[C@@H]1COC(=O)N1c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@@H]3F)cc2c1,HPK1,active,10.5,Ki,WO2018183964A1(1),10 nM to 100 nM
N#C[C@@H]1C[C@H]1C(=O)Nc1cc2cc(-n3c(=O)oc4ccccc43)cc(N)c2cn1,HPK1,active,75,Ki,US2018282282A1（HPK1）,10 nM to 100 nM
N#C[C@H]1C[C@@H]1C(=O)Nc1cc2cc(N3CC[C@H](O)C3=O)cc(N)c2cn1,HPK1,active,24,Ki,WO2018183964A1(1),10 nM to 100 nM
CC1CCC(=O)N1c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@@H]3F)cc2c1,HPK1,active,16,Ki,WO2018183964A1(1),10 nM to 100 nM
N#C[C@H]1C[C@@H]1C(=O)Nc1cc2cc(N3CC[C@@H](O)C3=O)cc(N)c2cn1,HPK1,active,91,Ki,WO2018183964A1(1),10 nM to 100 nM
Cn1ccc(=O)cc1-c1cc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3C#N)cc2c1,HPK1,active,65,Ki,WO2018183964A1(1),10 nM to 100 nM
CN(C)c1ccncc1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3C#N)cc2c1,HPK1,active,44,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3C#N)ncc2c(N)c1C,HPK1,active,15,Ki,WO2018183964A1(1),10 nM to 100 nM
CC1(C)CN(c2cc(N)c3cnc(NC(=O)C4CC4C#N)cc3c2)C(=O)O1,HPK1,active,14.8,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)C3CC3C#N)ncc2c(N)c1C,HPK1,active,15,Ki,WO2018183964A1(1),10 nM to 100 nM
Cn1ccc(=O)cc1-c1cc(N)c2cnc(NC(=O)C3CC3C#N)cc2c1,HPK1,active,65.3,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1cn2ccnc2cc1-c1cc(N)c2cnc(NC(=O)C3CC3C#N)cc2c1,HPK1,active,46.3,Ki,WO2018183964A1(1),10 nM to 100 nM
CCc1cc(OC(F)F)ncc1-c1cc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3C#N)cc2c1,HPK1,active,45.7,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1cc(C#N)ncc1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3C#N)cc2c1,HPK1,active,16.7,Ki,WO2018183964A1(1),10 nM to 100 nM
CC(F)(F)c1ccncc1-c1cc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3C#N)cc2c1,HPK1,active,11.5,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1cnccc1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3C#N)cc2c1,HPK1,active,15.8,Ki,WO2018183964A1(1),10 nM to 100 nM
CCOc1cc(CC)c(-c2cc(N)c3cnc(NC(=O)[C@H]4C[C@@H]4C#N)cc3c2)cn1,HPK1,active,13.4,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1cc2[nH]ncc2cc1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3C(N)=O)cc2c1,HPK1,active,13.8,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1cc2[nH]ncc2cc1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3C#N)cc2c1,HPK1,active,15.3,Ki,WO2018183964A1(1),10 nM to 100 nM
CNC(=O)c1ncc(-c2cc(N)c3cnc(NC(=O)[C@@H]4C[C@@H]4F)cc3c2)c(C)n1,HPK1,active,81.5,Ki,WO2018183964A1(1),10 nM to 100 nM
Nc1cc(-c2cnncc2C2CC2)cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc12,HPK1,active,19.5,Ki,WO2018183964A1(1),10 nM to 100 nM
Nc1cc(-c2cnccc2CO)cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc12,HPK1,active,15.8,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1nnc(-c2cccc(N3Cc4c(cc(C5(C)CC5)nc4CN)C3=O)n2)n1C1CCC1,HPK1,active,41,Ki,WO2020100027A1_Original_document_20201118034955,10 nM to 100 nM
CNCc1nc(C2(C)CC2)cc2c1CN(c1cccc(-c3nnc(C)n3C3CCC3)n1)C2=O,HPK1,active,26,Ki,WO2020100027A1_Original_document_20201118034955,10 nM to 100 nM
CC[C@@H](CC(F)(F)F)C1C=NN=C1c1cccc(N2Cc3c(cc(C4(C)CC4)nc3CNC)C2=O)n1,HPK1,active,25.09,Ki,AU2019378184A1（HPK1）Ki,10 nM to 100 nM
CNCc1nc(C(F)(F)F)cc2c1CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,89.9,Ki,WO2020100027A1_Original_document_20201118034955,10 nM to 100 nM
Cc1cn2ccnc2cc1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3C#N)cc2c1,HPK1,active,46,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1ccnc(-c2cnn(C)c2)c1-c1cc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)cc2c1,HPK1,active,23.5,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1coc(=O)n1-c1cc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3C#N)cc2c1,HPK1,active,14,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1ccnc(-c2ccnn2C)c1-c1cc(N)c2cnc(NC(=O)[C@H]3CC3c3cnn(C)c3)cc2c1,HPK1,active,16.1,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1ccnc(-c2ccnn2C)c1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3c3cnn(C)c3)cc2c1,HPK1,active,57.1,Ki,WO2018183964A1(1),10 nM to 100 nM
Cn1ncc2c(-c3cc(N)c4cnc(NC(=O)[C@H]5C[C@@H]5C#N)cc4c3)cncc21,HPK1,active,47.2,Ki,WO2018183964A1(1),10 nM to 100 nM
N#C[C@H]1C[C@@H]1C(=O)Nc1cc2cc(C3CNC(=O)O3)cc(N)c2cn1,HPK1,active,34,Ki,WO2018183964A1(1),10 nM to 100 nM
CC1CNC(=O)N1c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3C#N)cc2c1,HPK1,active,13,Ki,WO2018183964A1(1),10 nM to 100 nM
N#C[C@H]1C[C@@H]1C(=O)Nc1cc2cc(-n3c(=O)oc4ccccc43)cc(N)c2cn1,HPK1,active,75,Ki,WO2018183964A1(1),10 nM to 100 nM
CCn1cc(C)c(-c2cc(N)c3cnc(NC(=O)[C@@H]4C[C@@H]4F)cc3c2)cc1=O,HPK1,active,27.3,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC5)ncc3cc2F)cnc2c1[C@](C)(O)CCO2,HPK1,active,18,Ki,WO2020023560A1,10 nM to 100 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC5)ncc3cc2F)cnc2c1CNCCO2,HPK1,active,11,Ki,WO2020023560A1,10 nM to 100 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC5)ncc3cc2F)ccc2c1CNC2,HPK1,active,97,Ki,WO2020023560A1,10 nM to 100 nM
CNCc1cccc(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC5)ncc3cc2F)c1C,HPK1,active,64,Ki,WO2020023560A1,10 nM to 100 nM
Cc1cc(CN)ccc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC4)ncc2cc1F,HPK1,active,25,Ki,WO2020023560A1,10 nM to 100 nM
Cc1cc(CN)ncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC4)ncc2cc1F,HPK1,active,50,Ki,WO2020023560A1,10 nM to 100 nM
Cc1c(CN)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC4)ncc2cc1F,HPK1,active,19,Ki,WO2020023560A1,10 nM to 100 nM
CNCc1cncc(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC5)ncc3cc2F)c1C,HPK1,active,37,Ki,WO2020023560A1,10 nM to 100 nM
Cc1c(CN)cccc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC4)ncc2cc1F,HPK1,active,22,Ki,WO2020023560A1,10 nM to 100 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC5)ncc3cc2F)cnc(=O)n1C,HPK1,active,97,Ki,WO2020023560A1,10 nM to 100 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC5)ncc3cc2F)cnc2c1NS(=O)(=O)CO2,HPK1,active,23,Ki,WO2020023560A1,10 nM to 100 nM
Cc1cc(S(C)(=N)=O)ncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC4)ncc2cc1F,HPK1,active,23.7,Ki,WO2020023560A1,10 nM to 100 nM
CC(C)N1CCc2cc(Nc3cc4cc(C(=O)N5CCN(C)CC5)c(F)cc4cn3)nn2CC1=O,HPK1,active,63,Ki,WO2020023560A1,10 nM to 100 nM
Cc1ccncc1-c1cc2cc(Nc3cn4c(n3)CC(=O)N(C)CC4)ncc2c(Cl)c1F,HPK1,active,75,Ki,WO2020023560A1,10 nM to 100 nM
Fc1cccc(Cl)c1-c1ccc2cnc(Nc3ccncn3)cc2c1,HPK1,active,57,Ki,WO2020023560A1,10 nM to 100 nM
CN1CCC(CN2C=C(Nc3cc4cc(-c5c(Cl)cccc5Cl)ccc4cn3)C=[SH]2)C1,HPK1,active,68,Ki,WO2020023560A1,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2)C2(CN3)CC(CC(N)=O)C2)c1F,HPK1,active,67,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
Cn1cc(Nc2ccc3c(-c4cnc5c(c4)C4(CC4)CN5)c[nH]c3c2)cn1,HPK1,active,94,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(c1ccc2c(-c3cnc4c(c3)C3(CC3)CN4)c[nH]c2c1)c1cnn(C)c1,HPK1,active,74,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
N#CCc1ccc2[nH]cc(-c3cnc4c(c3)C3(CC3)CN4)c2c1,HPK1,active,73.4,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(c1cc(C#N)cc2c(-c3cnc4c(c3)C3(CC3)CN4)cn(C)c12)S(C)(=O)=O,HPK1,active,12.419,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(c1cc(C#N)cc2c(-c3cnc4c(c3)C3(CC3)CN4)c[nH]c12)S(C)(=O)=O,HPK1,active,14.7735,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
Fc1ccc2[nH]cc(-c3cnc4c(c3)C3(CC3)CN4)c2c1,HPK1,active,79.7,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CC1(C(N)=O)CCC2(CNc3ncc(-c4c[nH]c5ccc(C#N)cc45)c(Cl)c32)C1,HPK1,active,28.4,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
Cc1cc2[nH]cc(-c3cnc4c(c3)C3(CC3)CN4)c2cc1-c1cnn(C)c1,HPK1,active,46.62,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
c1nnc(-c2ccc3[nH]cc(-c4cnc5c(c4)C4(CC4)CN5)c3c2)o1,HPK1,active,48,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
c1cc2c(-c3cnc4c(c3)C3(CC3)CN4)c[nH]c2cn1,HPK1,active,42.277,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CC1(C#N)CCC2(CNc3ncc(-c4c[nH]c5ccc(C#N)cc45)c(Cl)c32)C1,HPK1,active,73.9,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
c1cc2[nH]cc(-c3cnc4c(c3)C3(CC3)CN4)c2cn1,HPK1,active,90,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
Cc1n[nH]cc1-c1ccc2[nH]cc(-c3cnc4c(c3)C3(CC3)CN4)c2c1,HPK1,active,76,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN1CCN(c2cc(C#N)cc3c(-c4cnc5c(c4)C4(CC4)CN5)c[nH]c23)C(=O)C1,HPK1,active,30.4,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
N#Cc1ccc2[nH]nc(-c3cnc4c(c3)C3(CC3)CN4)c2c1,HPK1,active,37.3,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
COc1c(-c2c[nH]c3ccc(C#N)cc23)cnc2c1C1(CC1)CN2,HPK1,active,34.4,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
Cc1ccc2[nH]cc(-c3cnc4c(c3)C3(CC3)CN4)c2c1,HPK1,active,73.1,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
Clc1ccc2[nH]cc(-c3cnc4c(c3)C3(CC3)CN4)c2c1,HPK1,active,45.9,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN1CCN(c2cc(Cl)cc3c(-c4cnc5c(c4)C4(CC4)CN5)c[nH]c23)C(=O)C1,HPK1,active,10.6,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
COc1c(-c2ccc(N)c(C(=O)N(C)C)n2)cnc2c1C1(CC1)CN2,HPK1,active,29,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
N#Cc1ccc2[nH]cc(-c3cnc4c(c3)C3(CC3)CN4)c2c1,HPK1,active,17.2,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CC1CC12CNc1ncc(-c3c[nH]c4c(N5CCNCC5=O)cccc34)cc12,HPK1,active,43.2,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
NC(=O)C1CCC2(CNc3ncc(-c4c[nH]c5c(N6CCNCC6=O)cccc45)c(Cl)c32)C1,HPK1,active,38.6,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN1CCN(c2cccc3c(-c4cnc5c(c4Cl)C4(CCC(C(N)=O)C4)CN5)c[nH]c23)C(=O)C1,HPK1,active,43.9,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
O=C1CNCCN1c1cccc2c(-c3cnc4c(c3)C3(CC3)CN4)c[nH]c12,HPK1,active,32.6,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
O=C1COCCN1c1cccc2c(-c3cnc4c(c3Cl)C3(CC3)CN4)c[nH]c12,HPK1,active,46.3,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)Cc1cccc2c(-c3cnc4c(c3Cl)C3(CC3)CN4)c[nH]c12,HPK1,active,68.2,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
O=C1CCCCN1c1cccc2c(-c3cnc4c(c3)C3(CC3)CN4)c[nH]c12,HPK1,active,88.9,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1cccc2c(-c3cnc4c(c3Cl)C3(CC3)CN4)c[nH]c12,HPK1,active,52.3,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1cccc2c(-c3cnc4c(c3)C3(CC3)CN4)c[nH]c12,HPK1,active,57.6,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
Cn1cccc(-c2cc(-c3cnc4c(c3Cl)C3(CC3)CN4)cc(N)n2)c1=O,HPK1,active,11.4,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
Nc1cc(-c2cnc3c(c2)C2(CC2)CN3)nc(N2CCCOC2=O)c1,HPK1,active,47.4,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1nc(-c2cnc3c(c2Cl)C2(CCC(C)(C#N)C2)CN3)ccc1N,HPK1,active,16,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
O=C1NCCC1c1nc2ccc(-c3cnc4c(c3Cl)C3(CC3)CN4)cc2[nH]1,HPK1,active,74.23,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CC1(C#N)C(=O)Nc2ccc(-c3cnc4c(c3)C3(CC3)CN4)cc21,HPK1,active,41.8,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)CCCN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(C)(C#N)C2)CN3)c1F,HPK1,active,41,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(S(C)(=O)=O)CC2)CN3)c1F,HPK1,active,44.8,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(CCN1CCOCC1)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(C)(C#N)C2)CN3)c1F,HPK1,active,30.8,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)CCN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(C)(C#N)C2)CN3)c1F,HPK1,active,24.9,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
N#CC1CCCCN1C(=O)c1cccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)c1F,HPK1,active,11.53,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(Cc1cnn(CCO)c1)C(=O)c1cccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)c1F,HPK1,active,12,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(Cc1cnn(C2CCNC2)c1)C(=O)c1cccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)c1F,HPK1,active,38,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
Cc1cc(CC#N)nn1-c1cccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)c1,HPK1,active,53.2,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(C(C)(C)O)CC2)CN3)c1F,HPK1,active,19.89,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
Cn1cc(C2CCCCN2C(=O)c2c(N)ccc(-c3cnc4c(c3)C3(CCC(O)CC3)CN4)c2F)cn1,HPK1,active,23.07,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
Cn1cc(C2CCCCN2C(=O)c2cccc(-c3cnc4c(c3)C3(CCC(O)CC3)CN4)c2F)cn1,HPK1,active,42.04,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
Cc1c(CC#N)ccnc1-c1cccc(-c2cnc3c(c2)C2(CC2)CN3)c1,HPK1,active,11.7,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(C#N)CC2)CN3)c1F,HPK1,active,44.8,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
Cc1cc(C)n(-c2cccc(-c3cnc4c(c3Cl)C3(CC=CC3)CN4)c2)n1,HPK1,active,22.89,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
NC(=O)C1(c2cccc(-c3cnc4c(c3Cl)C3(CC=CC3)CN4)c2)CC1,HPK1,active,33.16,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(C(N)=O)CC2)CN3)c1F,HPK1,active,46.73,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
Cc1c(-c2ccc(N)c(C(=O)N(C)C)c2F)cnc2c1C1(CCCCC1)CN2,HPK1,active,26.06,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
O=C(c1cccc(-c2cnc3c(c2)C2(CC2)CN3)c1F)N1CCCCC1,HPK1,active,33.7,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CC(c1cnn(C)c1)N(C)C(=O)c1cccc(-c2cnc3c(c2)C2(CC2)CN3)c1F,HPK1,active,11,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1cccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)c1F,HPK1,active,11.17,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1cccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)c1,HPK1,active,13.96,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CS(=O)(=O)Nc1cccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)c1,HPK1,active,70.85,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
O=S(=O)(Nc1ccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)cc1)C1CC1,HPK1,active,86.96,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CC1(C(N)=O)CCC2(CNc3ncc(-c4cccc(N5CCOCC5=O)c4F)c(Cl)c32)C1,HPK1,active,21.89,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CN3)CC2c2ccncc2)c1F,HPK1,active,15.24,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(n4ccccc4=O)C2)CN3)c1F,HPK1,active,97.61,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CC1(C#N)CCCN1C(=O)c1cccc(-c2cnc3c(c2)C2(CC2)CN3)c1F,HPK1,active,34.7,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CNS(=O)(=O)c1cccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)c1,HPK1,active,75.81,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CCS(=O)(=O)c1cccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)c1,HPK1,active,50.26,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CS(=O)(=O)c1cccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)c1,HPK1,active,30.28,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(n4cc(C(N)=O)cn4)C2)CN3)c1F,HPK1,active,46.13,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
Cc1cnn(C2CCC3(CNc4ncc(-c5ccc(N)c(C(=O)N(C)C)c5F)c(Cl)c43)C2)c1N,HPK1,active,15.91,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
Cc1cn(C2CCC3(CNc4ncc(-c5ccc(N)c(C(=O)N(C)C)c5F)c(Cl)c43)C2)nc1N,HPK1,active,14.72,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(n4nccc4C(F)(F)F)C2)CN3)c1F,HPK1,active,54.02,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(n4ccc(C(F)(F)F)n4)C2)CN3)c1F,HPK1,active,26.31,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
Cc1cc(C)n(C2CCC3(CNc4ncc(-c5ccc(N)c(C(=O)N(C)C)c5F)c(Cl)c43)C2)n1,HPK1,active,69.3,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
Cc1cc(C#N)n(C2CCC3(CNc4ncc(-c5ccc(N)c(C(=O)N(C)C)c5F)c(Cl)c43)C2)n1,HPK1,active,51.04,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
Cc1ccnn1C1CCC2(CNc3ncc(-c4ccc(N)c(C(=O)N(C)C)c4F)c(Cl)c32)C1,HPK1,active,56.54,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
Cc1ccn(C2CCC3(CNc4ncc(-c5ccc(N)c(C(=O)N(C)C)c5F)c(Cl)c43)C2)n1,HPK1,active,32.19,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
N#CC1CCCN1C(=O)c1cccc(-c2cnc3c(c2)C2(CC2)CN3)c1F,HPK1,active,14.2,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1cccc(-c2cnc3c(c2)C2(CC2)CN3)c1F,HPK1,active,33.5,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(CCC#N)C(=O)c1cccc(-c2cnc3c(c2)C2(CC2)CN3)c1F,HPK1,active,38.6,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CCN(C(=O)c1cccc(-c2cnc3c(c2)C2(CC2)CN3)c1F)C1CCC1,HPK1,active,34.1,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(Cc1cnn(C)c1)C(=O)c1cccc(-c2cnc3c(c2)C2(CC2)CN3)c1F,HPK1,active,15.9,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(n4nccc4N)C2)CN3)c1F,HPK1,active,16.07,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(n4ccc(N)n4)C2)CN3)c1F,HPK1,active,34,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(Cn4cncn4)C2)CN3)c1F,HPK1,active,23.43,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(n4cccn4)C2)CN3)c1F,HPK1,active,18.47,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(N4CCOC4=O)C2)CN3)c1F,HPK1,active,35.05,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(n4cnc(N)n4)C2)CN3)c1F,HPK1,active,76.77,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(N4CCNC4=O)C2)CN3)c1F,HPK1,active,22.98,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
COc1c(-c2ccc(N)c(C(=O)N(C)C)c2F)cnc2c1C1(CCC(O)CC1)CN2,HPK1,active,38.95,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(O)(CC#N)C2)CN3)c1F,HPK1,active,25.26,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(C(=O)N(C)C)C2)CN3)c1F,HPK1,active,50.1,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(C(=O)NCCO)C2)CN3)c1F,HPK1,active,23.57,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CC/C(=C\C#N)C2)CN3)c1F,HPK1,active,13.09,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2)C2(CN3)CC(=CC(N)=O)C2)c1F,HPK1,active,55.84,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(c4ncn[nH]4)C2)CN3)c1F,HPK1,active,14.54,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CNC(=O)C1CCC2(CNc3ncc(-c4ccc(N)c(C(=O)N(C)C)c4F)c(Cl)c32)C1,HPK1,active,75.61,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2)C2(CN3)CC(C(N)=O)C2)c1F,HPK1,active,50.68,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2)C2(CN3)CC(=CC#N)C2)c1F,HPK1,active,73.61,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
O=C1NCCC1c1cccc(-c2cnc3c(c2)C2(CC2)CN3)c1F,HPK1,active,28.4,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(C#N)C2)CN3)c1F,HPK1,active,80.43,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(n4ccnn4)C2)CN3)c1F,HPK1,active,51.79,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
COC1CCC2(CNc3ncc(-c4ccc(N)c(C(=O)N(C)C)c4F)c(Cl)c32)C1,HPK1,active,39.6,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
N#Cc1cc2c(-c3cnc4c(c3)C3(CC3)CN4)c[nH]c2cc1F,HPK1,active,31,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
O=C1NCCC1c1cccc(-c2cnc3c(c2Cl)C2(CC2)CN3)c1,HPK1,active,26.07,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CC1CNC(=O)N1c1cccc(-c2cnc3c(c2Cl)C2(CC2)CN3)c1,HPK1,active,35.62,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
O=C1NCCCN1c1cccc(-c2cnc3c(c2)C2(CC2)CN3)c1,HPK1,active,27.5,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2)C2(CCC2)CN3)c1F,HPK1,active,53.13,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CC(=O)Nc1ccc(-c2cnc3c(c2)C2(CC2)CN3)cc1C(F)(F)F,HPK1,active,89.1,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CS(=O)(=O)c1cccc(-c2cnc3c(c2)C2(CC2)CN3)c1,HPK1,active,84.9,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
NS(=O)(=O)c1cccc(-c2cnc3c(c2)C2(CC2)CN3)c1,HPK1,active,66.4,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
Nc1cc(-c2cnc3c(c2Cl)C2(CCC(O)C2)CN3)cc(-c2ncccc2CO)c1,HPK1,active,12.84,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
O=C1CCCCN1c1cccc(-c2cnc3c(c2Cl)C2(CC2)CN3)c1,HPK1,active,16.01,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
O=C1NCCCN1c1cccc(-c2cnc3c(c2Cl)C2(CC2)CN3)c1,HPK1,active,14.25,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
O=C1NCCCC1c1cccc(-c2cnc3c(c2Cl)C2(CC2)CN3)c1,HPK1,active,43.71,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
N#Cc1cc2c(-c3cnc4c(c3)C3(CC3)CN4)c[nH]c2cn1,HPK1,active,35.314,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
O=C1NCCN1c1cccc(-c2cnc3c(c2Cl)C2(CC2)CN3)c1,HPK1,active,84.71,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CC(=O)Nc1cc(C#N)cc2c(-c3cnc4c(c3)C3(CC3)CN4)cn(C)c12,HPK1,active,64.37,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
Cc1c(-c2ccc(N)c(C(=O)N(C)C)c2F)cnc2c1C1(CCC1)CN2,HPK1,active,28.86,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
COc1c(-c2ccc(N)c(C(=O)N(C)CCO)c2F)cnc2c1C1(CCC1)CN2,HPK1,active,19,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
NC1CN(C(=O)c2cccc(-c3cnc4c(c3Cl)C3(CC3)CN4)c2F)C1,HPK1,active,68.211,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
O=C(c1cccc(-c2cnc3c(c2Cl)C2(CC2)CN3)c1F)N1CC(O)C1,HPK1,active,55.29,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
O=C(c1cccc(-c2cnc3c(c2Cl)C2(CC2)CN3)c1F)N(CCO)CCO,HPK1,active,88.47,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CCN(CCO)C(=O)c1cccc(-c2cnc3c(c2Cl)C2(CC2)CN3)c1F,HPK1,active,38.64,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(CCO)C(=O)c1cccc(-c2cnc3c(c2Cl)C2(CC2)CN3)c1F,HPK1,active,43.69,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
OCc1cccnc1-c1cccc(-c2cnc3c(c2)C2(CC2)CN3)c1,HPK1,active,81.5,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CN3)Cc3ccncc3C2)c1F,HPK1,active,15.32,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CN3)CC2CO)c1F,HPK1,active,17.23,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(CC(C)(C)O)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CC2)CN3)c1F,HPK1,active,22.8,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
Nc1ccc(-c2cnc3c(c2Cl)C2(CC2)CN3)cc1C(=O)N1C2CCC1CC2,HPK1,active,12.79,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
COc1c(-c2ccc(N)c(C(=O)N(C)C)c2F)cnc2c1C1(CC1)CN2,HPK1,active,28.57,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
Cc1c(-c2ccc(N)c(C(=O)N(C)C)c2F)cnc2c1C1(CC1)CN2,HPK1,active,53.86,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(CC(C)(C)O)C(=O)c1c(N)ccc(-c2cnc3c(c2)C2(CC2)CN3)c1F,HPK1,active,30,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CC1CNC(=O)N1c1c(N)ccc(-c2cnc3c(c2Cl)C2(CC2)CN3)c1F,HPK1,active,43.9,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2)C2(CN3)CC2(C)C)c1F,HPK1,active,88.66,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C(=O)c1c(N)ccc(-c2cnc3c(c2)C2(CC2)CN3)c1F)C(C)(C)CO,HPK1,active,20.8,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
Nc1ccc(-c2cnc3c(c2)C2(CC2)CN3)c(F)c1C(=O)N1CCCC1CO,HPK1,active,32.8,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CC1(C)C(=O)Nc2ccc(-c3cnc4c(c3)C3(CC3)CN4)cc21,HPK1,active,21.6,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(CCO)C(=O)c1cccc(-c2cnc3c(c2)C2(CC2)CN3)c1F,HPK1,active,37.6,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
NS(=O)(=O)Cc1ccc(-c2cnc3c(c2)C2(CC2)CN3)cc1,HPK1,active,91.2,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
Nc1cc(-c2cnc3c(c2)C2(CC2)CN3)cc(-c2ncccc2CO)c1,HPK1,active,12.7,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
O=C1COCCN1c1cccc(-c2cnc3c(c2)C2(CC2)CN3)c1F,HPK1,active,38.9,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(CCO)C(=O)c1c(N)ccc(-c2cnc3c(c2)C2(CC2)CN3)c1F,HPK1,active,21.6,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2)C2(CC2)CN3)c1F,HPK1,active,22.67,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
O=C1COCCN1c1cccc(-c2cnc3c(c2)C2(CCC2)CN3)c1,HPK1,active,98.72,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1cc(-c2cnc3c(c2)C2(CCC2)CN3)ccc1N,HPK1,active,71.66,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1cc(-c2cnc3c(c2)C2(CC2)CN3)ccc1N,HPK1,active,35.56,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
CN(C)C(=O)c1cc(-c2cnc3c(c2)C2(CCCC2)CN3)ccc1N,HPK1,active,28.79,Ki,WO2020061377A1_Original_document_20201118034029,10 nM to 100 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CCOC4)ncc3c(N)c2F)cnc2c1[C@H](O)CC2,HPK1,active,93,Ki,WO2020072695A1,10 nM to 100 nM
CN[C@@H]1CCCC[C@H]1OC(=O)Nc1cc2cc(-c3cnc4c(c3C)NCCO4)c(F)c(N)c2cn1,HPK1,active,16,Ki,WO2020072695A1,10 nM to 100 nM
Cc1c(-c2cc3cc(NC(=O)O[C@@H]4CCCC[C@H]4NC(C)O)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,21,Ki,WO2020072695A1,10 nM to 100 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CC[C@@H]4C#N)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,13,Ki,WO2020072695A1,10 nM to 100 nM
Cc1c(-c2cc3cc(NC(=O)OC4CCOCC4)ncc3c(N)c2F)cnc2c1[C@H](O)CCO2,HPK1,active,41,Ki,WO2020072695A1,10 nM to 100 nM
Cc1cc(-c2ccn(C)n2)ncc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,20,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1cc(N2CCC2=O)ncc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,21,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
COCc1cccc(C)c1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,51,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)C3C4CC(NS(C)(=O)=O)CC43)ncc2c(N)n1,HPK1,active,96,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1nc2c(=O)n(C)ncc2c(C)c1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,33,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1c(-c2cc3cc(NC(=O)[C@@H]4C[C@H]4c4cnn(C)c4)ncc3c(N)n2)cnc2c(=O)n(C)ncc12,HPK1,active,20,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
COc1cncc(-c2cc3cc(NC(=O)[C@@H]4C[C@H]4c4cnn(C)c4)ncc3c(N)n2)c1C,HPK1,active,34,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
COCc1cc(C)c(-c2cc3cc(NC(=O)[C@H]4C[C@@H]4c4cnn(C)c4)ncc3c(N)n2)cn1,HPK1,active,19,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
COC(=O)[C@@H]1COC(c2cc(C)c(-c3cc4cc(NC(=O)[C@@H]5C[C@H]5c5cnn(C)c5)ncc4c(N)n3)cn2)=N1,HPK1,active,20,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1cccc(CC#N)c1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,14,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1cc(-c2ncco2)ccc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,22,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1cc(-c2nc(C(C)C)co2)ccc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,15,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1cc(-c2nc(C(C)C)co2)ccc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,96,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1cc(-c2nc(-c3ccccc3)co2)ccc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,12,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1cc(-c2nc(-c3ccccc3)co2)ccc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,75,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1cc(-c2ncco2)cc(F)c1-c1cc2cc(NC(=O)[C@H]3[C@@H](C)[C@@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,39.7,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cn1cc([C@H]2C[C@@H]2C(=O)Nc2cc3cc(-c4cnc(N)c(C(F)(F)F)c4)nc(N)c3cn2)cn1,HPK1,active,11.8,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NCC3CC3(F)F)ncc2c(N)n1,HPK1,active,61.3,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1cc(-c2ccccc2)ncc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3CC#N)ncc2c(N)n1,HPK1,active,20.4,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3CC[C@@H]3C)ncc2c(N)n1,HPK1,active,76.3,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3CC[C@H]3C)ncc2c(N)n1,HPK1,active,14.8,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3CC[C@H]3C)ncc2c(N)n1,HPK1,active,57.4,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@]34CCNC(=O)C4)ncc2c(N)n1,HPK1,active,12.2,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@]34CCNC(=O)C4)ncc2c(N)n1,HPK1,active,13.1,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1ccc(C(=O)N(C)C)cc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,active,63.8,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1cc(Nc2cc3cc(-c4cnccc4C)nc(N)c3cn2)n(CCO)n1,HPK1,active,36.7,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)C3[C@H]4CN(C5COC5)C[C@@H]34)ncc2c(N)n1,HPK1,active,33.9,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C(C)(C)O)ncc2c(N)n1,HPK1,active,31.2,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
COC(C)(C)[C@H]1C[C@@H]1C(=O)Nc1cc2cc(-c3cnccc3C)nc(N)c2cn1,HPK1,active,47,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1cc(-c2cnn(C)c2)ncc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3CC#N)ncc2c(N)n1,HPK1,active,10.2,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
N#C[C@H]1C[C@@H]1C(=O)Nc1cc2cc(-c3cnccc3-c3cn[nH]c3)nc(N)c2cn1,HPK1,active,23.3,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
COCCc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C#N)ncc2c(N)n1,HPK1,active,21.2,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
COCc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C#N)ncc2c(N)n1,HPK1,active,11,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
N#CCc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C#N)ncc2c(N)n1,HPK1,active,38.7,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
CNC(=O)c1cncc(-c2cc3cc(NC(=O)[C@@H]4C[C@@H]4F)ncc3c(N)n2)c1C,HPK1,active,58.6,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
CC(C)(O)Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C=N)ncc2c(N)n1,HPK1,active,84.2,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
N#Cc1ccccc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C#N)ncc2c(N)n1,HPK1,active,15.2,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)C3CC3(C)CO)ncc2c(N)n1,HPK1,active,30.7,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
CC(=O)OC[C@@]1(C)C[C@@H]1C(=O)Nc1cc2cc(-c3cnccc3C)nc(N)c2cn1,HPK1,active,17.1,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3ncccn3)ncc2c(N)n1,HPK1,active,10,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1nn(C)c(C)c1-c1cc2cc(NC(=O)C3CC3C(F)(F)F)ncc2c(N)n1,HPK1,active,12,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1[nH]ncc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3C(F)(F)F)ncc2c(N)n1,HPK1,active,16,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1cc(C)c(-c2cc3cc(NC(=O)[C@@H]4C[C@H]4C#N)ncc3c(N)n2)cc1C(N)=O,HPK1,active,89,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
CNC(=O)c1c(C)c(-c2cc3cc(NC(=O)[C@H]4C[C@@H]4C#N)ncc3c(N)n2)c(C)n1C,HPK1,active,44,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
CC(=O)Nc1cc2c(F)c(-c3cnccc3C)nc(N)c2cn1,HPK1,active,21,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)C3C4CN(S(C)(=O)=O)CC43)ncc2c(N)n1,HPK1,active,15,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1c(-c2cc3cc(NC(=O)[C@H]4C[C@@H]4C#N)ncc3c(N)n2)cncc1C(F)F,HPK1,active,39,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C(=O)N(C)C)ncc2c(N)n1,HPK1,active,32,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)O[C@@H]3CCNC3=O)ncc2c(N)n1,HPK1,active,15,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
CCc1ccncc1-c1cc2cc(NCc3ccn[nH]3)ncc2c(N)n1,HPK1,active,40.2,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1ncc(-c2cc3cc(NC(=O)C4CC4C#N)ncc3c(N)n2)n1C,HPK1,active,18.9,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
CCc1ccncc1-c1cc2cc(NC(=O)Cc3ccn[nH]3)ncc2c(N)n1,HPK1,active,21.5,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1cnc(C#N)cc1-c1cc2cc(NC(=O)C3CC3F)ncc2c(N)n1,HPK1,active,22.5,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1cnc(CO)cc1-c1cc2cc(NC(=O)C3CC3F)ncc2c(N)n1,HPK1,active,18.3,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
N#CC1CC1C(=O)Nc1cc2cc(-c3cncc4c3CCCC4O)nc(N)c2cn1,HPK1,active,70.7,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1c(F)cncc1-c1cc2cc(NC(=O)C3CC3F)ncc2c(N)n1,HPK1,active,16.1,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
CCc1ccncc1-c1cc2cc(NC(=O)c3cnn(C)c3)ncc2c(N)n1,HPK1,active,13.4,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
CCc1ccncc1-c1cc2cc(NC(=O)c3ccnn3C)ncc2c(N)n1,HPK1,active,14.1,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
CCc1ccncc1-c1cc2cc(NC(=O)c3cc[nH]n3)ncc2c(N)n1,HPK1,active,10,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
CCc1ccncc1-c1cc2cc(NC(=O)c3cc(C)[nH]n3)ncc2c(N)n1,HPK1,active,27.6,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
CCc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@@H]3C(N)=O)ncc2c(N)n1,HPK1,active,25.8,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
CCc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@@H]3C#N)ncc2c(N)n1,HPK1,active,10.6,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1cc(C(C)(C)O)ncc1-c1cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc2c(N)n1,HPK1,active,41.7,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Nc1nc(N2CCCC2CCO)cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc12,HPK1,active,48.9,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1cc(C(N)=O)ccc1-c1cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc2c(N)n1,HPK1,active,10.3,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
CCC1CCCN1c1cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc2c(N)n1,HPK1,active,11.7,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Nc1nc(-c2cnccc2CO)cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc12,HPK1,active,48,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Nc1nc(-c2ccc[nH]c2=O)cc2cc(NC(=O)C3CC3)ncc12,HPK1,active,40.5,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Nc1nc(N2CCOC2=O)cc2cc(NC(=O)C3CC3)ncc12,HPK1,active,98,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H](C)C#N)ncc2c(N)n1,HPK1,active,48.4,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)C(C)C)ncc2c(N)n1,HPK1,active,29.8,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
CCc1ccncc1-c1cc2cc(NC(=O)N[C@H](C)C(N)=O)ncc2c(N)n1,HPK1,active,34,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
CCc1ccncc1-c1cc2cc(NC(=O)N(C)C)ncc2c(N)n1,HPK1,active,34.1,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
CCc1ccncc1-c1cc2cc(NC(=O)CC#N)ncc2c(N)n1,HPK1,active,26.4,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
CCc1ccncc1-c1cc2cc(NC(=O)CCC(N)=O)ncc2c(N)n1,HPK1,active,14,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
CCc1ccncc1-c1cc2cc(NC(=O)CCC#N)ncc2c(N)n1,HPK1,active,14.9,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cn1nccc1-c1cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc2c(N)n1,HPK1,active,47.5,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1c(F)cncc1-c1cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc2c(N)n1,HPK1,active,16.1,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
N#Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc2c(N)n1,HPK1,active,22.6,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
CCc1ncncc1-c1cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc2c(N)n1,HPK1,active,15.6,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1ncncc1-c1cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc2c(N)n1,HPK1,active,49.3,Ki,WO2018183956A1_Original_document_20201230132016,10 nM to 100 nM
Cc1c(-c2cc3cc(NC(=O)OCC(C)N)ncc3cc2F)cnc2c1NCCO2,HPK1,active,29,Ki,WO2020072627A1_Original_document_20201119122058,10 nM to 100 nM
Cc1c(N)cncc1-c1cc2cc(NC(=O)OCC3CC3)ncc2cc1F,HPK1,active,45,Ki,WO2020072627A1_Original_document_20201119122058,10 nM to 100 nM
Cc1c(-c2cc3cc(NC(=O)OC[C@H]4CCCN4)ncc3cc2F)cnc2c1NCCO2,HPK1,active,25,Ki,WO2020072627A1_Original_document_20201119122058,10 nM to 100 nM
Cc1c(-c2cc3cc(NC(=O)N[C@@H](C)c4cnn(C)c4)ncc3cc2F)cnc2c1NCCO2,HPK1,active,10,Ki,WO2020072627A1_Original_document_20201119122058,10 nM to 100 nM
Cc1c(-c2cc3cc(NC(=O)OCC45CC4CCN5)ncc3cc2F)cnc2c1NCCO2,HPK1,active,24,Ki,WO2020072627A1_Original_document_20201119122058,10 nM to 100 nM
Cc1c(-c2cc3cc(NC(=O)OC45CC6CC(CC(C6)C4)C5)ncc3cc2F)cnc2c1NCCO2,HPK1,active,35,Ki,WO2020072627A1_Original_document_20201119122058,10 nM to 100 nM
Cc1c(-c2cc3cc(NC(=O)OCCN)ncc3cc2F)cnc2c1NCCO2,HPK1,active,32,Ki,WO2020072627A1_Original_document_20201119122058,10 nM to 100 nM
Cc1c(N)cncc1-c1ccc2nnc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)cc2c1,HPK1,active,40,Ki,WO2020069402A1_Original_document_20201120091428,10 nM to 100 nM
Nc1cc(-c2cnccc2C2CC2)cc2cc(NC(=O)C3CC3F)nnc12,HPK1,active,31,Ki,WO2020069402A1_Original_document_20201120091428,10 nM to 100 nM
CCc1ccncc1-c1cc(N)c2nnc(NC(=O)C3CC3C#N)cc2c1,HPK1,active,13,Ki,WO2020069402A1_Original_document_20201120091428,10 nM to 100 nM
Cn1cc(-c2cc(N)c3nnc(NC(=O)C4CC4C#N)cc3c2)cn1,HPK1,active,14,Ki,WO2020069402A1_Original_document_20201120091428,10 nM to 100 nM
Cn1cc(-c2cc(N)c3nnc(NC(=O)[C@@H]4C[C@@H]4F)cc3c2)cn1,HPK1,active,15,Ki,WO2020069402A1_Original_document_20201120091428,10 nM to 100 nM
Cc1ccncc1-c1cc(N)c2nnc(NC(=O)[C@@H]3C[C@@H]3F)cc2c1,HPK1,active,53,Ki,WO2020069402A1_Original_document_20201120091428,10 nM to 100 nM
CCc1ccncc1-c1cc(N)c2nnc(NC(=O)NCC(F)(F)F)cc2c1,HPK1,active,22,Ki,WO2020069402A1_Original_document_20201120091428,10 nM to 100 nM
CCc1ccncc1-c1cc(N)c2nnc(NC(=O)N3CCCC3)cc2c1,HPK1,active,31,Ki,WO2020069402A1_Original_document_20201120091428,10 nM to 100 nM
CCc1ccncc1-c1cc(N)c2nnc(NC(=O)NC3CCOC3)cc2c1,HPK1,active,11,Ki,WO2020069402A1_Original_document_20201120091428,10 nM to 100 nM
Cn1cc(-c2cc(N)c3nnc(NC(=O)N4CCCC4)cc3c2)cn1,HPK1,active,65,Ki,WO2020069402A1_Original_document_20201120091428,10 nM to 100 nM
CC(C)OC(=O)Nc1cc2cc(-c3cnn(C)c3)cc(N)c2nn1,HPK1,active,28,Ki,WO2020069402A1_Original_document_20201120091428,10 nM to 100 nM
CC(C)NC(=O)Nc1cc2cc(-c3cnn(C)c3)cc(N)c2nn1,HPK1,active,21,Ki,WO2020069402A1_Original_document_20201120091428,10 nM to 100 nM
Cc1cc(N)ncc1-c1cc(N)c2nnc(NC(=O)[C@@H]3C[C@@H]3F)cc2c1,HPK1,active,15,Ki,WO2020069402A1_Original_document_20201120091428,10 nM to 100 nM
COc1ccncc1-c1cc(N)c2nnc(NC(=O)[C@@H]3C[C@@H]3F)cc2c1,HPK1,active,58,Ki,WO2020069402A1_Original_document_20201120091428,10 nM to 100 nM
CCn1cc(-c2cc(N)c3nnc(NC(=O)[C@@H]4C[C@@H]4F)cc3c2)cn1,HPK1,active,84,Ki,WO2020069402A1_Original_document_20201120091428,10 nM to 100 nM
Cc1ccncc1-c1cc2cc(Nc3ccc(CCO)cn3)ncc2cn1,HPK1,active,28,Ki,WO2020023551A1_Original_document_20201120101107,10 nM to 100 nM
CNS(=O)(=O)c1ccc(Nc2cc3cc(-c4cnccc4C)ncc3cn2)nc1,HPK1,active,11,Ki,WO2020023551A1_Original_document_20201120101107,10 nM to 100 nM
Cc1ccncc1-c1cc2cc(Nc3ccc(C(=O)N(C)C)cn3)ncc2cn1,HPK1,active,24,Ki,WO2020023551A1_Original_document_20201120101107,10 nM to 100 nM
CNCc1cc(C)c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC5)ncc3cn2)c(F)c1,HPK1,active,13,Ki,WO2020023551A1_Original_document_20201120101107,10 nM to 100 nM
CCC1=C(C)NC2N=CC(c3ccc(N)c(C(=O)N(C)C)c3)=CC12,HPK1,active,15,Ki,WO2018167147A1_Original_document_20201120072807,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3[nH]c(Cl)c(CCO)c3c2Cl)c1F,HPK1,active,12,Ki,WO2018167147A1_Original_document_20201120072807,10 nM to 100 nM
CCc1c(Cl)[nH]c2ncc(-c3cccc(C4NCCNC4=O)c3)cc12,HPK1,active,31,Ki,WO2018167147A1_Original_document_20201120072807,10 nM to 100 nM
CCc1c(Cl)[nH]c2ncc(-c3ccc(C4NCCNC4=O)cc3)cc12,HPK1,active,32,Ki,WO2018167147A1_Original_document_20201120072807,10 nM to 100 nM
O=C1COCCN1c1cccc(-c2cnc3[nH]c(Cl)c(CCO)c3c2)c1,HPK1,active,89,Ki,WO2018167147A1_Original_document_20201120072807,10 nM to 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3[nH]c(Cl)c(CCO)c3c2)c1F,HPK1,active,17,Ki,WO2018167147A1_Original_document_20201120072807,10 nM to 100 nM
Cc1[nH]c2ncc(-c3cccc(N4CCNCC4=O)n3)cc2c1C(F)(F)F,HPK1,active,82,Ki,WO2018167147A1_Original_document_20201120072807,10 nM to 100 nM
Cc1[nH]c2ncc(-c3cccc(N4CCOCC4CO)n3)cc2c1C(F)(F)F,HPK1,active,75,Ki,WO2018167147A1_Original_document_20201120072807,10 nM to 100 nM
O=C1COCCN1c1cccc(-c2cnc3[nH]c(Cl)c(CCF)c3c2)c1,HPK1,active,17,Ki,WO2018167147A1_Original_document_20201120072807,10 nM to 100 nM
Cc1[nH]c2ncc(-c3ccc(N)c(N4CCOCC4=O)n3)cc2c1C(F)(F)F,HPK1,active,13,Ki,WO2018167147A1_Original_document_20201120072807,10 nM to 100 nM
CCc1c(Cl)[nH]c2ncc(-c3ccnc(N4CCOC4=O)n3)cc12,HPK1,active,33,Ki,WO2018167147A1_Original_document_20201120072807,10 nM to 100 nM
Cc1[nH]c2ncc(-c3cc(N)cc(-c4ncccc4CO)c3)cc2c1C(F)(F)F,HPK1,active,24,Ki,WO2018167147A1_Original_document_20201120072807,10 nM to 100 nM
Cc1[nH]c2ncc(-c3ccc(N)c(C(=O)N(C)C)c3)cc2c1C(F)(F)F,HPK1,active,32,Ki,WO2018167147A1_Original_document_20201120072807,10 nM to 100 nM
Cc1[nH]c2ncc(-c3ccc(N)c(C(=O)N(C)C)n3)cc2c1C(F)(F)F,HPK1,active,76,Ki,WO2018167147A1_Original_document_20201120072807,10 nM to 100 nM
Cc1[nH]c2ncc(-c3cccc(N4CCOCC4=O)c3)cc2c1C(F)(F)F,HPK1,active,68,Ki,WO2018167147A1_Original_document_20201120072807,10 nM to 100 nM
CCc1c(Cl)[nH]c2ncc(C3=CC(C(=O)N4CC(O)C4)C(N)C=C3)cc12,HPK1,active,15,Ki,WO2018167147A1_Original_document_20201120072807,10 nM to 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2N2C[C@H]3C[C@]2(CO)CN3)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COC[C@H]1CCN1c1ccc(NC(=O)c2ccnc(-c3c(F)cccc3OC)n2)c(N2C[C@H]3C[C@@H]2CN3)c1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(CO)ccc2N2C[C@@H]3C[C@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1ccc(N2C[C@@H]3C[C@H]2CN3)c(NC(=O)c2ccnc(-c3c(F)cccc3OC)n2)c1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CCCNC(=O)N1C[C@@H]2C[C@H]1CN2c1ccc(F)cc1NC(=O)c1ccnc(-c2c(F)cccc2OC)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CCN1C[C@@H]2C[C@H]1CN2c1ccc(F)cc1NC(=O)c1ccnc(-c2c(F)cccc2OC)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c(CNC3CCC3)cc2N2C[C@H]3C[C@@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c(N3CCC3)cc2N2C[C@H]3C[C@@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c(N3CCOCC3)cc2N2C[C@H]3C[C@@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2N2C[C@H]3C[C@@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1ccncc1-c1ccc(NC(=O)c2ccnc(-c3c(F)cccc3OC)n2)c(N2C[C@H]3C[C@@H]2CN3)c1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c(-c3cccnc3C)cc2N2C[C@H]3C[C@@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c(-c3ccc(=O)n(C)c3)cc2N2C[C@H]3C[C@@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CNC(=O)c1ccc(-c2cc(N3C[C@H]4C[C@@H]3CN4)c(NC(=O)c3ccnc(-c4c(F)cccc4OC)n3)cc2F)cn1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c(-c3ccc(CO)nc3)cc2N2C[C@H]3C[C@@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c(-c3cnn(C)c3)cc2N2C[C@H]3C[C@@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c(Br)cc2N2C[C@H]3C[C@@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c(CO)cc2N2C[C@H]3C[C@@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)cc(-c3cnn(C)c3)c2N2C[C@@H]3C[C@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)cc(-c3cccnc3)c2N2C[C@@H]3C[C@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cccc(C#N)c2N2C[C@@H]3C[C@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)ccc2N2CCNC[C@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)ccc2N2C[C@@H]3C[C@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
Cc1cc2c(c(F)c1-c1cc3c(-c4cnn(C)c4)n[nH]c3cn1)CCC2N,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COCCn1ncc2c(N3C[C@@H](N)C[C@H]3CO)c(NC(=O)c3cccc(-c4c(F)cccc4OC)n3)cc(F)c21,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3c(cnn3C)c2N(C)[C@@H]2CCCNC2)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COCCn1ncc2c(N3C[C@@H](N)C[C@H]3CO)c(NC(=O)c3ccnc(-c4c(OC)ccc(-c5cnn(C)c5)c4F)n3)cc(F)c21,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
CNC(=O)c1ccc(OC)c(-c2nccc(C(=O)Nc3cc(F)c4c(cnn4CCOC)c3N3C[C@@H](N)C[C@H]3CO)n2)c1F,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COCCn1ncc2c(N3C[C@@H](N)C[C@H]3CO)c(NC(=O)c3ccnc(-c4c(F)cc(N)cc4OC)n3)cc(F)c21,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3c(cnn3CCF)c2N2C[C@@H]3C[C@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3c(cnn3C)c2N2C[C@@H](O)C[C@H]2CN)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3c(cnn3-c3ccncc3C#N)c2N2C[C@@H](N)C[C@H]2CO)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3nn(C)cc3c2N2CCN[C@@H](CO)C2)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3c(cnn3C3CCOC3)c2N2C[C@@H](N)C[C@H]2CO)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COCCn1ncc2c(N3C[C@@H](N)C[C@H]3CO)c(NC(=O)c3ccnc(-c4c(F)cccc4OC)n3)cc(F)c21,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(c(-c4cnn(C)c4)nn3C)c2N2CCC(N(C)C)CC2)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(c(C)nn3C)c2N2CCC(N(C)C)CC2)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(c(I)nn3C)c2N2CCC(N(C)C)CC2)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COCCn1ncc2c(N3C[C@@H]4C[C@H]3CN4)c(NC(=O)c3ccnc(-c4c(F)cccc4OC)n3)cc(F)c21,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3c(cnn3CCO)c2N2C[C@H]3C[C@@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3c(cnn3C)c2-c2cccc(CN(C)C)c2)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3c(cnn3C)c2-c2ccccc2CO)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3c(cnn3C)c2-c2cccc(CO)c2)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3c(cnn3C)c2-c2cccnc2)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(C)c3nn(C)cc3c2N2CC[C@@H](N)C2)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(C)c3nn(C)cc3c2N2CCNCC2)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(C)c3c(cnn3C)c2N2CCNCC2)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3c(cnn3CCO)c2N2CC[C@@H](N)C2)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
CNC(=O)c1cc(NC(=O)c2ccnc(-c3c(F)cccc3OC)n2)c(N2CCC[C@@H](N)C2)c2cn(C)nc12,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(C#N)c3nn(C)cc3c2N2CCC[C@@H](N)C2)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(C#N)c3c(cnn3C)c2N2CCC[C@@H](N)C2)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3nn(C)cc3c2-c2ccccc2C)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3c(cnn3C)c2-c2ccccc2C)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3c(cnn3C)c2-n2cccn2)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3c(cnn3C)c2N2CCCC2=O)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3c(cnn3C)c2C2CCNC2)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3nn(C)cc3c2N2CCC[C@@H]2CN)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3c(cnn3C)c2N2CCC[C@@H]2CN)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3c(cnn3C)c2N2CC(N)C2)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3c(cnn3C)c2N2CCC3(CCNC3=O)C2)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3nn(C)cc3c2N2CCC3(CCNC3=O)C2)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3nn(C)cc3c2N2CCOCC2)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3c(cnn3C)c2N2CCOCC2)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3nn(C)cc3c2N2CCC[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3c(cnn3C)c2N2CCC[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3nn(C)cc3c2N2C[C@@H]3CC[C@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3c(cnn3C)c2N2C[C@@H]3CC[C@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3nn(C)cc3c2N2CC[C@@H](N)C2)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3c(cnn3C)c2N2CC[C@@H](N)C2)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3nn(C)cc3c2N2C[C@@H](N)C[C@H]2CO)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3c(cnn3C)c2N2C[C@@H](N)C[C@H]2CO)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
CCNC(=O)N1C[C@@H]2C[C@H]1CN2c1c(NC(=O)c2ccnc(-c3c(F)cccc3OC)n2)cc(F)c2c1cnn2C,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3nn(C)cc3c2N2C[C@@H]3C[C@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c3c(cnn3C)c2N2C[C@@H]3C[C@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
CNCc1cc(F)c(C2=NC=C3NN=C(c4ccc(N5CCCC(C)(CO)C5)nc4)C3N2)c(F)c1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CCN1CCN(c2ccc(C3=NNC4=CN=C(c5c(F)cc(CNC)cc5F)NC43)cc2)CC1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
O=C1CNCCN1c1cccc(-c2cnc3c(c2)C2(CC2)CN3)c1,HPK1,medium,100,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
COc1ncc([C@H](C)N)c2cc(Nc3ccnc(C(C)(C)F)n3)ncc12,HPK1,active,21.5,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc([C@@H](C)N)c2cc(Nc3ccnc(C(C)(C)F)n3)ncc12,HPK1,active,21.5,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CNc1ncc(C(C)(C)N)c2cc(Nc3cnc(C#N)c(C(C)C)n3)ncc12,HPK1,active,11.14,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CCOc1ncc(C(C)(C)NC)c2cc(Nc3ccnc(C(C)(C)F)n3)ncc12,HPK1,active,11.46,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3cnc4c(n3)CC(C)(C)OC4=O)ncc12,HPK1,active,13.58,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C2CCCN2)c2cc(Nc3ccc4c(n3)CC(C)(C)OC4=O)ncc12,HPK1,active,52.56,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)N)c2cc(Nc3cnc(C#N)c(C(C)C(F)(F)F)n3)ncc12,HPK1,active,6.46,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)Cc2nc(Nc3cc4c(C(C)(C)N)cnc(OC5CC5)c4cn3)ccc2C(=O)O1,HPK1,active,0.44,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1c2nc(Nc3cc4c(C(C)(C)N)cnc(OC5CC5)c4cn3)ccc2C(=O)O[C@@H]1C,HPK1,active,0.56,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c(C(C)(C)N)cnc(OC5CC5)c4cn3)nc2[C@H]1C,HPK1,active,0.18,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CCOc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)[C@@H](C)C(C)(C)OC4=O)ncc12,HPK1,active,0.12,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CCOc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)[C@H](C)C(C)(C)OC4=O)ncc12,HPK1,active,0.27,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)Oc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)CC(C)(C)OC4=O)ncc12,HPK1,active,0.88,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1c2nc(Nc3cc4c(C(C)(C)N)cnc(OC5CC5)c4cn3)ccc2C(=O)OC1(C)C,HPK1,active,0.35,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1c2nc(Nc3cc4c(C(C)(C)N)cnc(OC5CC5)c4cn3)ccc2C(=O)OC1(C)C,HPK1,active,0.11,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)Cc2nc(Nc3cc4c(C(C)(C)N)cnc(OC5CCC5)c4cn3)ccc2C(=O)O1,HPK1,active,0.41,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)Cc2nc(Nc3cc4c(C(C)(C)N)cnc(OCC(F)F)c4cn3)ccc2C(=O)O1,HPK1,active,0.22,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)Cc2nc(Nc3cc4c([C@](C)(N)C5CC5)cnc(OC5CC5)c4cn3)ccc2C(=O)O1,HPK1,active,0.12,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c([C@](C)(N)C5CC5)cnc(OC5CC5)c4cn3)nc2[C@H]1C,HPK1,active,0.09,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1c2nc(Nc3cc4c([C@](C)(N)C5CC5)cnc(OC5CC5)c4cn3)ccc2C(=O)OC1(C)C,HPK1,active,0.12,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c(C(C)(C)N)cnc(OCC(F)(F)F)c4cn3)nc2[C@H]1C,HPK1,active,0.19,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1c2nc(Nc3cc4c(C(C)(C)N)cnc(OCC(F)(F)F)c4cn3)ccc2C(=O)OC1(C)C,HPK1,active,0.26,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)[C@@H](C)[C@H](C)OC4=O)cc12,HPK1,active,0.08,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c(C(C)(C)N)cnc(OC5(C)CC5)c4cn3)nc2[C@H]1C,HPK1,active,0.16,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1c2nc(Nc3cc4c(C(C)(C)N)cnc(OC5(C)CC5)c4cn3)ccc2C(=O)OC1(C)C,HPK1,active,0.19,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@](C)(N)c1cnc(OC2(C)CC2)c2cnc(Nc3ccc4c(n3)[C@@H](C)[C@H](C)OC4=O)cc12,HPK1,active,1.32,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@](C)(N)c1cnc(OC2(C)CC2)c2cnc(Nc3ccc4c(n3)[C@@H](C)[C@H](C)OC4=O)cc12,HPK1,active,1.32,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@](C)(N)c1cnc(OC2(C)CC2)c2cnc(Nc3ccc4c(n3)[C@@H](C)C(C)(C)OC4=O)cc12,HPK1,active,2.03,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@](C)(N)c1cnc(OC2(C)CC2)c2cnc(Nc3ccc4c(n3)[C@@H](C)C(C)(C)OC4=O)cc12,HPK1,active,2.03,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c([C@@](C)(N)C5CC5)cnc(OC5(C)CC5)c4cn3)nc2[C@H]1C,HPK1,active,0.16,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c([C@](C)(N)C5CC5)cnc(OC5(C)CC5)c4cn3)nc2[C@H]1C,HPK1,active,0.16,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1c2nc(Nc3cc4c([C@@](C)(N)C5CC5)cnc(OC5(C)CC5)c4cn3)ccc2C(=O)OC1(C)C,HPK1,active,3.42,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1c2nc(Nc3cc4c([C@](C)(N)C5CC5)cnc(OC5(C)CC5)c4cn3)ccc2C(=O)OC1(C)C,HPK1,active,3.42,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@](C)(N)c1cnc(OC2(C)CC2)c2cnc(Nc3ccc4c(n3)[C@@H](C)[C@@H](C)OC4=O)cc12,HPK1,active,0.25,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@](C)(N)c1cnc(OC2(C)CC2)c2cnc(Nc3ccc4c(n3)[C@H](C)[C@H](C)OC4=O)cc12,HPK1,active,0.25,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@](C)(N)c1cnc(OC2(C)CC2)c2cnc(Nc3ccc4c(n3)[C@@H](C)[C@@H](C)OC4=O)cc12,HPK1,active,0.25,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@](C)(N)c1cnc(OC2(C)CC2)c2cnc(Nc3ccc4c(n3)[C@H](C)[C@H](C)OC4=O)cc12,HPK1,active,0.25,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1OC(=O)c2ccc(Nc3cc4c([C@@](C)(N)C5CC5)cnc(OC5(C)CC5)c4cn3)nc2[C@H]1C,HPK1,active,0.14,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@](N)(c1cnc(OC2(C)CC2)c2cnc(Nc3ccc4c(n3)[C@H](C)[C@H](C)OC4=O)cc12)C1CC1,HPK1,active,0.14,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1OC(=O)c2ccc(Nc3cc4c([C@](C)(N)C5CC5)cnc(OC5(C)CC5)c4cn3)nc2[C@H]1C,HPK1,active,0.14,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c([C@](C)(N)C5CC5)cnc(OC5(C)CC5)c4cn3)nc2[C@@H]1C,HPK1,active,0.14,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)[C@@H](C)[C@@H](C)OC4=O)cc12,HPK1,active,0.14,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)[C@H](C)[C@H](C)OC4=O)cc12,HPK1,active,0.14,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)[C@@H](C)[C@@H](C)OC4=O)cc12,HPK1,active,0.14,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)[C@H](C)[C@H](C)OC4=O)cc12,HPK1,active,0.14,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc([C@](C)(N)C2CC2)c2cc(Nc3ccc4c(n3)C(C)(C)OC4=O)ncc12,HPK1,active,0.36,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc([C@@](C)(N)C2CC2)c2cc(Nc3ccc4c(n3)C(C)(C)OC4=O)ncc12,HPK1,active,0.36,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc([C@](C)(N)C2CC2)c2cc(Nc3ccc4c(n3)[C@@H](C)[C@H](C)OC4=O)ncc12,HPK1,active,0.13,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc([C@@](C)(N)C2CC2)c2cc(Nc3ccc4c(n3)[C@@H](C)[C@H](C)OC4=O)ncc12,HPK1,active,0.13,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc([C@](C)(N)C2CC2)c2cc(Nc3ccc4c(n3)[C@@H](C)C(C)(C)OC4=O)ncc12,HPK1,active,0.11,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc([C@@](C)(N)C2CC2)c2cc(Nc3ccc4c(n3)[C@@H](C)C(C)(C)OC4=O)ncc12,HPK1,active,0.11,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(C(C)(C)N)c2cc(Nc3ccc4c(n3)CC(C)(C)OC4=O)ncc12,HPK1,active,0.11,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)Cc2nc(Nc3cc4c(C(C)(C)N)ccc(Cl)c4cn3)ccc2C(=O)O1,HPK1,active,0.13,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)C(C)(C)OC4=O)cc12,HPK1,active,2.09,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@](N)(c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)CCNC4=O)cc12)C1CC1,HPK1,active,0.61,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)C3(CC3)COC4=O)cc12,HPK1,active,0.62,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@](N)(c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)CCOC4=O)cc12)C1CC1,HPK1,active,0.98,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c(C(C)(C)N)cnc(NC5CC5)c4cn3)nc2[C@H]1C,HPK1,active,0.21,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)[C@@](C)(CC)OC4=O)cc12,HPK1,active,0.11,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)C(C)(C)COC4=O)cc12,HPK1,active,0.23,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@]1(C)OC(=O)c2ccc(Nc3cc4c(C(C)(C)N)cnc(OC5CC5)c4cn3)nc21,HPK1,active,0.58,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@]1(C)OC(=O)c2ccc(Nc3cc4c(C(C)(C)N)cnc(OC5CC5)c4cn3)nc21,HPK1,active,0.58,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(N)c1cnc(OCC(F)F)c2cnc(Nc3ccc4c(n3)C(C)(C)OC4=O)cc12,HPK1,active,2.14,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1COC(=O)c2ccc(Nc3cc4c([C@](C)(N)C5CC5)cnc(OC5CC5)c4cn3)nc21,HPK1,active,0.24,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1COC(=O)c2ccc(Nc3cc4c([C@](C)(N)C5CC5)cnc(OC5CC5)c4cn3)nc21,HPK1,active,0.24,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1OC(=O)c2ccc(Nc3cc4c(C(C)(C)N)cnc(OC5CC5)c4cn3)nc2C12CC2,HPK1,active,0.12,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c(C(C)(C)N)cnc(OC5CC5)c4cn3)nc2C12CC2,HPK1,active,0.12,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@](C)(N)c1cnc(NC2CC2)c2cnc(Nc3ccc4c(n3)[C@@H](C)[C@H](C)OC4=O)cc12,HPK1,active,0.9,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1c2nc(Nc3cc4c(C(C)(C)N)cnc(NC5CC5)c4cn3)ccc2C(=O)OC1(C)C,HPK1,active,0.2,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c(C(C)(C)N)cnc(NC5CCC5)c4cn3)nc2[C@H]1C,HPK1,active,0.24,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)CCc2nc(Nc3cc4c(C(C)(C)N)cnc(OC5CC5)c4cn3)ccc2C(=O)O1,HPK1,active,1.84,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1OC(=O)c2ccc(Nc3cc4c(C(C)(C)N)cnc(OC5CC5)c4cn3)nc2C1(C)C,HPK1,active,0.17,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c(C(C)(C)N)cnc(OC5CC5)c4cn3)nc2C1(C)C,HPK1,active,0.17,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1c2nc(Nc3cc4c(C(C)(C)N)cnc(OC5CC5)c4cn3)ccc2C(=O)O[C@H]1C,HPK1,active,1.09,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1c2nc(Nc3cc4c(C(C)(C)N)cnc(OC5CC5)c4cn3)ccc2C(=O)O[C@@H]1C,HPK1,active,1.09,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@]1(C)OC(=O)c2ccc(Nc3cc4c([C@](C)(N)CC)cnc(OC5CC5)c4cn3)nc21,HPK1,active,0.11,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)[C@@](C)(CC)OC4=O)cc12,HPK1,active,0.11,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1OC(=O)c2ccc(Nc3cc4c(C(C)(C)N)cnc(OC5CC5)c4cn3)nc2[C@@H]1C,HPK1,active,0.46,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)CC(C)(C)OC4=O)cc12,HPK1,active,0.18,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)CC(C)(C)OC4=O)cc12,HPK1,active,0.18,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)Cc2nc(Nc3cc4c(C(C)(C)N)cnc(OC5(C)CC5)c4cn3)ccc2C(=O)O1,HPK1,active,0.54,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)C(C)(C)COC4=O)cc12,HPK1,active,0.39,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c([C@](C)(N)CO)cnc(OC5CC5)c4cn3)nc2[C@H]1C,HPK1,active,2.25,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c([C@@](C)(N)CO)cnc(OC5CC5)c4cn3)nc2[C@H]1C,HPK1,active,2.25,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c(C(C)(C)N)cnc(OC5COC5)c4cn3)nc2[C@H]1C,HPK1,active,0.42,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CCCOc1ncc([C@](C)(N)CC)c2cc(Nc3ccc4c(n3)[C@@H](C)[C@H](C)OC4=O)ncc12,HPK1,active,0.2,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CCCOc1ncc([C@@](C)(N)CC)c2cc(Nc3ccc4c(n3)[C@@H](C)[C@H](C)OC4=O)ncc12,HPK1,active,0.2,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CCCOc1ncc([C@](C)(N)CC)c2cc(Nc3ccc4c(n3)CC(C)(C)OC4=O)ncc12,HPK1,active,0.31,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CCCOc1ncc([C@@](C)(N)CC)c2cc(Nc3ccc4c(n3)CC(C)(C)OC4=O)ncc12,HPK1,active,0.31,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@](N)(c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)C3(CC3)COC4=O)cc12)C1CC1,HPK1,active,0.25,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@](N)(c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)CC3(CC3)OC4=O)cc12)C1CC1,HPK1,active,0.27,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)Cc2nc(Nc3cc4c([C@](C)(N)C5CC5)cnc(OC5CC5)c4cn3)ccc2C(=O)N1,HPK1,active,0.11,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c([C@](C)(N)C5CC5)cnc(NC5CC5)c4cn3)nc2[C@H]1C,HPK1,active,0.2,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c([C@@](C)(N)C5CC5)cnc(NC5CC5)c4cn3)nc2[C@H]1C,HPK1,active,0.2,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)COC(=O)c2ccc(Nc3cc4c([C@](C)(N)C5CC5)cnc(OC5CC5)c4cn3)nc21,HPK1,active,0.22,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@]1(C)OC(=O)c2ccc(Nc3cc4c([C@](C)(N)C5CC5)cnc(OC5CC5)c4cn3)nc21,HPK1,active,0.42,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@]1(C)OC(=O)c2ccc(Nc3cc4c([C@](C)(N)C5CC5)cnc(OC5CC5)c4cn3)nc21,HPK1,active,0.42,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)Cc2nc(Nc3cc4c([C@@](C)(N)C5CC5)cnc(OC5CC5)c4cn3)ccc2C(=O)O1,HPK1,active,2.61,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1OC(=O)c2ccc(Nc3cc4c([C@](C)(N)C5CC5)cnc(OC5CC5)c4cn3)nc2[C@H]1C,HPK1,active,0.08,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c([C@](C)(N)C5CC5)cnc(OC5CC5)c4cn3)nc2[C@@H]1C,HPK1,active,0.08,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)[C@@H](C)C(C)(C)OC4=O)cc12,HPK1,active,0.1,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)[C@@H](C)C(C)(C)OC4=O)cc12,HPK1,active,0.1,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)C(C)(C)[C@@H](C)OC4=O)cc12,HPK1,active,0.14,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)C(C)(C)[C@H](C)OC4=O)cc12,HPK1,active,0.14,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)C(C)(C)[C@@H](C)OC4=O)cc12,HPK1,active,0.14,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncc(C(C)(C)NC2CCC2)c2cc(Nc3ccc4c(n3)CC(C)(C)OC4=O)ncc12,HPK1,active,6.46,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c(C(C)(C)N)cnc(O[C@H]5CCOC5)c4cn3)nc2[C@H]1C,HPK1,active,0.39,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c(C(C)(C)N)cnc(O[C@@H]5CCOC5)c4cn3)nc2[C@H]1C,HPK1,active,1.25,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c(C(C)(C)N)cnc(O[C@H]5C[C@H](F)C5)c4cn3)nc2[C@H]1C,HPK1,active,1.37,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c(C(C)(C)N)cnc(OCC5(F)CC5)c4cn3)nc2[C@H]1C,HPK1,active,0.24,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c(C(C)(C)N)cnc(O[C@H]5C[C@@H](F)C5)c4cn3)nc2[C@H]1C,HPK1,active,0.25,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](Oc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)CC(C)(C)OC4=O)ncc12)C(F)F,HPK1,active,7.35,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H](Oc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)CC(C)(C)OC4=O)ncc12)C(F)F,HPK1,active,7.35,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c(C(C)(C)N)cnc(OCC(C)(F)F)c4cn3)nc2[C@H]1C,HPK1,active,0.25,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1OC(=O)c2ccc(Nc3cc4c([C@](C)(N)C5CC5)cnc(OC5CC5)c4cn3)nc2C12CC2,HPK1,active,0.05,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c([C@](C)(N)C5CC5)cnc(OC5CC5)c4cn3)nc2C12CC2,HPK1,active,0.05,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)Cc2nc(Nc3cc4c([C@](C)(N)C5CCC5)cnc(OC5CC5)c4cn3)ccc2C(=O)O1,HPK1,active,0.15,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)Cc2nc(Nc3cc4c([C@@](C)(N)C5CCC5)cnc(OC5CC5)c4cn3)ccc2C(=O)O1,HPK1,active,0.15,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c([C@](C)(N)C5CCC5)cnc(OC5CC5)c4cn3)nc2[C@H]1C,HPK1,active,0.07,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c([C@@](C)(N)C5CCC5)cnc(OC5CC5)c4cn3)nc2[C@H]1C,HPK1,active,0.07,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1OC(=O)c2ccc(Nc3cc4c([C@](C)(N)C5CC5)cnc(OC5CC5)c4cn3)nc2C1(C)C,HPK1,active,0.07,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c([C@](C)(N)C5CC5)cnc(OC5CC5)c4cn3)nc2C1(C)C,HPK1,active,0.07,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@]1(C)OC(=O)c2ccc(Nc3cc4c(C(C)(C)N)cnc(OCC(F)(F)F)c4cn3)nc21,HPK1,active,4.47,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@]1(C)OC(=O)c2ccc(Nc3cc4c(C(C)(C)N)cnc(OCC(F)(F)F)c4cn3)nc21,HPK1,active,4.47,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@](C)(N)c1cnc(OCC(F)(F)F)c2cnc(Nc3ccc4c(n3)C(C)(C)OC4=O)cc12,HPK1,active,1.72,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@](C)(N)c1cnc(OCC(F)(F)F)c2cnc(Nc3ccc4c(n3)C(C)(C)OC4=O)cc12,HPK1,active,1.72,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(N)c1cnc(OCC(F)(F)F)c2cnc(Nc3ccnc([C@H]4CCC[C@H](O)C4)n3)cc12,HPK1,active,0.8,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(N)c1cnc(OCC(F)(F)F)c2cnc(Nc3ccnc([C@@H]4CCC[C@@H](O)C4)n3)cc12,HPK1,active,0.8,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)Cc2nc(Nc3cc4c(C(C)(C)NCCO)cnc(OC5CC5)c4cn3)ccc2C(=O)O1,HPK1,active,6.52,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c(C(C)(C)N)cnc(OC5CC(F)(F)C5)c4cn3)nc2[C@H]1C,HPK1,active,0.29,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H](Oc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)CC(C)(C)OC4=O)ncc12)C(F)(F)F,HPK1,active,2.12,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](Oc1ncc(C(C)(C)N)c2cc(Nc3ccc4c(n3)CC(C)(C)OC4=O)ncc12)C(F)(F)F,HPK1,active,2.12,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@](C)(N)c1cnc(OCC(F)(F)F)c2cnc(Nc3ccc4c(n3)[C@@H](C)[C@H](C)OC4=O)cc12,HPK1,active,0.18,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@](C)(N)c1cnc(OCC(F)(F)F)c2cnc(Nc3ccc4c(n3)[C@@H](C)[C@H](C)OC4=O)cc12,HPK1,active,0.18,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)Cc2nc(Nc3cc4c(C(C)(C)NC5COC5)cnc(OC5CC5)c4cn3)ccc2C(=O)O1,HPK1,active,26.35,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COC[C@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)[C@H](C)[C@@H](C)OC4=O)cc12,HPK1,active,0.27,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COC[C@@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)[C@H](C)[C@@H](C)OC4=O)cc12,HPK1,active,0.27,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC1(Oc2ncc([C@](C)(N)C3CC3)c3cc(Nc4ccc5c(n4)C(C)(C)COC5=O)ncc23)CC1,HPK1,active,0.35,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC1(Oc2ncc([C@@](C)(N)C3CC3)c3cc(Nc4ccc5c(n4)C(C)(C)COC5=O)ncc23)CC1,HPK1,active,0.35,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c(C(C)(C)N)cnc(OC5(C)CC5)c4cn3)nc2C1(C)C,HPK1,active,0.4,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1OC(=O)c2ccc(Nc3cc4c(C(C)(C)N)cnc(OC5(C)CC5)c4cn3)nc2C1(C)C,HPK1,active,0.4,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)C3(CC3)[C@@H](C)OC4=O)cc12,HPK1,active,0.06,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)C3(CC3)[C@H](C)OC4=O)cc12,HPK1,active,0.06,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COC[C@@](C)(N)c1cnc(OC)c2cnc(Nc3ccc4c(n3)[C@@H](C)[C@H](C)OC4=O)cc12,HPK1,active,0.09,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COC[C@](C)(N)c1cnc(OC)c2cnc(Nc3ccc4c(n3)[C@@H](C)[C@H](C)OC4=O)cc12,HPK1,active,0.09,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COC[C@@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)[C@@H](C)C(C)(C)OC4=O)cc12,HPK1,active,0.16,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COC[C@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)[C@@H](C)C(C)(C)OC4=O)cc12,HPK1,active,0.16,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COC[C@@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)[C@@H](C)[C@@H](C)OC4=O)cc12,HPK1,active,0.19,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COC[C@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)[C@@H](C)[C@@H](C)OC4=O)cc12,HPK1,active,0.19,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COC[C@@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)[C@H](C)[C@H](C)OC4=O)cc12,HPK1,active,0.19,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COC[C@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)[C@H](C)[C@H](C)OC4=O)cc12,HPK1,active,0.19,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H](N)c1cnc(OC2(C)CC2)c2cnc(Nc3ccc4c(n3)[C@@H](CC)C(C)(C)OC4=O)cc12,HPK1,active,0.53,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](N)c1cnc(OC2(C)CC2)c2cnc(Nc3ccc4c(n3)[C@@H](C)C(C)(C)OC4=O)cc12,HPK1,active,0.53,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COC[C@@](C)(N)c1cnc(OC)c2cnc(Nc3ccc4c(n3)[C@@H](C)[C@@H](C)OC4=O)cc12,HPK1,active,0.19,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COC[C@](C)(N)c1cnc(OC)c2cnc(Nc3ccc4c(n3)[C@@H](C)[C@@H](C)OC4=O)cc12,HPK1,active,0.19,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COC[C@@](C)(N)c1cnc(OC)c2cnc(Nc3ccc4c(n3)[C@H](C)[C@H](C)OC4=O)cc12,HPK1,active,0.19,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COC[C@](C)(N)c1cnc(OC)c2cnc(Nc3ccc4c(n3)[C@H](C)[C@H](C)OC4=O)cc12,HPK1,active,0.19,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c([C@@](C)(N)C5CC5)cnc(O[C@H]5C[C@H](O)C5)c4cn3)nc2[C@H]1C,HPK1,active,0.1,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c([C@](C)(N)C5CC5)cnc(O[C@H]5C[C@H](O)C5)c4cn3)nc2[C@H]1C,HPK1,active,0.1,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H](N)c1cnc(OC)c2cnc(Nc3ccc4c(n3)[C@@H](C)[C@H](C)OC4=O)cc12,HPK1,active,0.33,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](N)c1cnc(OC)c2cnc(Nc3ccc4c(n3)[C@@H](CC)[C@H](C)OC4=O)cc12,HPK1,active,0.33,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)C3(CC3)C(C)(C)OC4=O)cc12,HPK1,active,0.1,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)C3(CC3)C(C)(C)OC4=O)cc12,HPK1,active,0.1,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OC(=O)c2ccc(Nc3cc4c(C(C)(C)N)cnc(OC5(C)COC5)c4cn3)nc2[C@H]1C,HPK1,active,0.34,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1c2nc(Nc3cc4c(C(C)(C)N)cnc(OC5(C)COC5)c4cn3)ccc2C(=O)OC1(C)C,HPK1,active,0.27,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC1(Oc2ncc(C(C)(C)N)c3cc(Nc4ccc5c(n4)C4(CC4)C(C)(C)OC5=O)ncc23)CC1,HPK1,active,0.36,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COC[C@@](C)(N)c1cnc(OC)c2cnc(Nc3ccc4c(n3)[C@@H](C)C(C)(C)OC4=O)cc12,HPK1,active,0.14,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COC[C@](C)(N)c1cnc(OC)c2cnc(Nc3ccc4c(n3)[C@@H](C)C(C)(C)OC4=O)cc12,HPK1,active,0.14,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H](N)c1cnc(C)c2cnc(Nc3ccc4c(n3)[C@@H](C)[C@H](C)OC4=O)cc12,HPK1,active,0.62,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](N)c1cnc(C)c2cnc(Nc3ccc4c(n3)[C@@H](C)[C@H](C)OC4=O)cc12,HPK1,active,0.62,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H](N)c1cnc(OC)c2cnc(Nc3ccc4c(n3)[C@@H](C)C(C)(C)OC4=O)cc12,HPK1,active,0.22,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](N)c1cnc(OC)c2cnc(Nc3ccc4c(n3)[C@@H](C)C(C)(C)OC4=O)cc12,HPK1,active,0.22,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COC[C@@](C)(N)c1cnc(C)c2cnc(Nc3ccc4c(n3)[C@@H](C)C(C)(C)OC4=O)cc12,HPK1,active,0.19,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H](N)c1ccc(OC)c2cnc(Nc3ccc4c(n3)C3(CC3)C(C)(C)OC4=O)cc12,HPK1,active,0.22,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](N)c1ccc(OC)c2cnc(Nc3ccc4c(n3)C3(CC3)C(C)(C)OC4=O)cc12,HPK1,active,0.22,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1c2nc(Nc3cc4c([C@H](N)COC)cnc(OC)c4cn3)ccc2C(=O)OC1(C)C,HPK1,active,0.7,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COC[C@H](N)c1cnc(OC)c2cnc(Nc3ccc4c(n3)[C@@H](C)C(C)(C)OC4=O)cc12,HPK1,active,0.7,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H](N)c1ccc(Cl)c2cnc(Nc3ccc4c(n3)[C@@H](C)C(C)(C)OC4=O)cc12,HPK1,active,0.39,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](N)c1ccc(Cl)c2cnc(Nc3ccc4c(n3)[C@@H](CC)C(C)(C)OC4=O)cc12,HPK1,active,0.39,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)Cc2nc(Nc3cc4c(C(C)(C)N)cnc(OCC(F)(F)F)c4cn3)ccc2C(=O)O1,HPK1,active,0.65,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)[C@@H](C)[C@H](C)OC4=O)cc12,HPK1,active,0.08,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@](C)(N)c1cnc(NC2CC2)c2cnc(Nc3ccc4c(n3)[C@@H](C)[C@H](C)OC4=O)cc12,HPK1,active,0.9,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)[C@](C)(CC)OC4=O)cc12,HPK1,active,0.11,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1OC(=O)c2ccc(Nc3cc4c(C(C)(C)N)cnc(OC5CC5)c4cn3)nc2[C@H]1C,HPK1,active,0.46,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)C(C)(C)COC4=O)cc12,HPK1,active,0.39,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)C(C)(C)[C@H](C)OC4=O)cc12,HPK1,active,0.14,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)C3(CC3)[C@@H](C)OC4=O)cc12,HPK1,active,0.06,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)C3(CC3)[C@H](C)OC4=O)cc12,HPK1,active,0.06,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)C3(CC3)C(C)(C)OC4=O)cc12,HPK1,active,0.27,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COC[C@@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)CC(C)(C)OC4=O)cc12,HPK1,active,0.48,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
COC[C@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4c(n3)CC(C)(C)OC4=O)cc12,HPK1,active,0.48,ic50,WO2021146370A1_Blueprint, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc2cc(NC(=O)C3CC3C#N)ncc2c(N)c1C#N,HPK1,active,1.39,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)[C@H]3[C@@H](C)[C@@H]3CC#N)cc2c1,HPK1,active,2.2,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC4C)ncc2c(N)c1F,HPK1,active,0.079,Ki,WO2018183964A1(1),Below 1 nM
CC[C@H]1[C@H](C(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)c(N)c3cn2)[C@H]1c1cnn(C)c1,HPK1,active,0.228,Ki,WO2018183964A1(1),Below 1 nM
CC[C@H]1[C@@H](C(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)c(N)c3cn2)[C@@H]1c1cnn(C)c1,HPK1,active,0.054,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(-c2cc3cc(NC(=O)[C@@H]4[C@@H](C)[C@H]4c4cnn(C)c4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.014,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3C#N)ncc2c(N)c1F,HPK1,active,0.26,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(N)ncc2c(N)c1C#N,HPK1,active,15,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1c(-c2cc3cc(NC(=O)N[C@@H](C)c4cnn(C)c4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.168,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc2cc(NC(=O)[C@H]3[C@H](c4cnn(C)c4)C3(C)C)ncc2c(N)c1F,HPK1,active,27,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1c(N)cncc1-c1cc2cc(NC(=O)[C@@H]3[C@H]4COC[C@H]43)ncc2c(N)c1F,HPK1,active,0.78,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc2cc(NC(=O)[C@@H]3[C@@H](CC#N)[C@H]3C)ncc2c(N)c1F,HPK1,active,0.11,Ki,WO2018183964A1(1),Below 1 nM
CCS(=O)(=O)Nc1cc(N)c2cnc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)cc2c1,HPK1,active,30.6,Ki,WO2018183964A1(1),10 nM to 100 nM
CC(C)N1CCc2cc(Nc3cc4cc(-c5cncc(N)c5Cl)c(F)c(N)c4cn3)nn2CC1=O,HPK1,active,0.016,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)Cc3nccn3CC4)ncc2c(N)c1F,HPK1,active,0.13,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(F)(F)CCC4C)ncc2c(N)c1F,HPK1,active,0.31,Ki,WO2018183964A1(1),Below 1 nM
CO[C@@H]1CC[C@@H](C)c2cc(Nc3cc4cc(-c5cncc(N)c5C)c(F)c(N)c4cn3)nn2C1,HPK1,active,2.6,Ki,WO2018183964A1(1),1 nM to 10 nM
CC(C)N1CCc2cc(Nc3cc4cc(-c5cnc6n5CCNC6)c(F)c(N)c4cn3)nn2CC1=O,HPK1,active,22,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CS(=O)(=O)CCC4)ncc2c(N)c1F,HPK1,active,0.17,Ki,WO2018183964A1(1),Below 1 nM
Cc1c[nH]c(=O)cc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)ncc2c(N)c1F,HPK1,active,1.9,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(CC3COC3)CC4)ncc2c(N)c1F,HPK1,active,0.013,Ki,WO2018183964A1(1),Below 1 nM
COc1ncc(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(CC(F)F)CC5)ncc3c(N)c2F)c(C)c1N,HPK1,active,0.96,Ki,WO2018183964A1(1),Below 1 nM
CC[C@@H]1[C@H](C(=O)Nc2cc3cc(-c4cncc(N)c4C)c(F)c(N)c3cn2)[C@H]1c1cnn(C)c1,HPK1,active,1.8,Ki,WO2018183964A1(1),1 nM to 10 nM
CC[C@H]1[C@H](C(=O)Nc2cc3cc(-c4cncc(N)c4C)c(F)c(N)c3cn2)[C@H]1c1cnn(C)c1,HPK1,active,0.91,Ki,WO2018183964A1(1),Below 1 nM
CCc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)ncc2c(N)c1F,HPK1,active,0.013,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CS(=O)(=O)N(C)CC4C)ncc2c(N)c1F,HPK1,active,0.2,Ki,WO2018183964A1(1),Below 1 nM
CCN1CCc2cc(Nc3cc4cc(-c5cncc(N)c5C)c(F)c(N)c4cn3)nn2CC1=O,HPK1,active,0.017,Ki,WO2018183964A1(1),Below 1 nM
Cc1ncc(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC5)ncc3c(N)c2F)c(C)c1N,HPK1,active,0.017,Ki,WO2018183964A1(1),Below 1 nM
Cc1[nH]ncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC4)ncc2c(N)c1F,HPK1,active,2.8,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)C4)ncc2c(N)c1F,HPK1,active,0.365,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)C/C4=C\c3cnn(C)c3)ncc2c(N)c1F,HPK1,active,0.024,Ki,WO2018183964A1(1),Below 1 nM
Cc1n[nH]c(C)c1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC4)ncc2c(N)c1F,HPK1,active,2.1,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(CC(F)(F)F)CC4)ncc2c(N)c1F,HPK1,active,0.019,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC4F)ncc2c(N)c1F,HPK1,active,0.013,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(CC(F)F)CC4)ncc2c(N)c1F,HPK1,active,0.015,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)ncc2c(N)c1F,HPK1,active,0.013,Ki,WO2018183964A1(1),Below 1 nM
Cc1cc(-c2ncco2)ncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC4C)ncc2c(N)c1F,HPK1,active,0.013,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@@H](c4cnc[nH]4)[C@H]3C)ncc2c(N)c1F,HPK1,active,0.99,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3[C@@H](C)[C@@H]3c3cnc[nH]3)ncc2c(N)c1F,HPK1,active,0.86,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3[C@@H](C)[C@@H]3c3ccn[nH]3)ncc2c(N)c1F,HPK1,active,50.12,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@@H](c4ccn[nH]4)[C@H]3C)ncc2c(N)c1F,HPK1,active,1.3,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@H](C)[C@H]3c3ccn[nH]3)ncc2c(N)c1F,HPK1,active,4.6,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)C3CC3c3cnc[nH]3)ncc2c(N)c1F,HPK1,active,0.83,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cnc[nH]3)ncc2c(N)c1F,HPK1,active,9.4,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnc[nH]3)ncc2c(N)c1F,HPK1,active,0.22,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)N3CC4CC3C4)ncc2c(N)c1F,HPK1,active,18,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@H]3CN(C)C)ncc2c(N)c1F,HPK1,active,5,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@H](C)[C@H]3c3cnn(CCN4CCOCC4)c3)ncc2c(N)c1F,HPK1,active,7.2,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@@H](c4cnn(CCN5CCOCC5)c4)[C@H]3C)ncc2c(N)c1F,HPK1,active,0.22,Ki,WO2018183964A1(1),Below 1 nM
Cc1cc(-c2ncco2)ncc1-c1cc2cc(NC(=O)[C@@H]3[C@@H](c4cnn(C)c4)[C@H]3C)ncc2c(N)c1F,HPK1,active,1.6,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1cc(-c2ncco2)ncc1-c1cc2cc(NC(=O)[C@@H]3[C@H](C)[C@H]3c3cnn(C)c3)ncc2c(N)c1F,HPK1,active,16,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cn(C)nn3)ncc2c(N)c1F,HPK1,active,0.84,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cn(C)nn3)ncc2c(N)c1F,HPK1,active,2.2,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1c(N)cncc1-c1cc2cc(NC(=O)[C@@H]3[C@H](C)[C@H]3c3cnn(C)c3)ncc2c(N)c1F,HPK1,active,0.026,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc2cc(NC(=O)[C@@H]3[C@@H](c4cnn(C)c4)[C@H]3C)ncc2c(N)c1F,HPK1,active,0.21,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc2cc(NC(=O)[C@@H]3[C@@H](C)[C@H]3c3cnn(C)c3)ncc2c(N)c1F,HPK1,active,1.2,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)C[C@H]4C)ncc2c(N)c1F,HPK1,active,0.034,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@H](C)[C@H]3c3cnn(CCO)c3)ncc2c(N)c1F,HPK1,active,3.6,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C(c4c[nH]cn4)[C@H]3c3cnn(C)c3)ncc2c(N)c1F,HPK1,active,25.6,Ki,WO2018183964A1(1),10 nM to 100 nM
CC[C@H]1[C@@H](C(=O)Nc2cc3cc(-c4cncc(N)c4C)c(F)c(N)c3cn2)[C@@H]1c1cncn1C,HPK1,active,12,Ki,WO2018183964A1(1),10 nM to 100 nM
CC[C@@H]1[C@H](C(=O)Nc2cc3cc(-c4cncc(N)c4C)c(F)c(N)c3cn2)[C@H]1c1cncn1C,HPK1,active,22,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@H](C)[C@H]3c3cnn(CCN4CC(O)C4)c3)ncc2c(N)c1F,HPK1,active,5.8,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@@H](CC#N)[C@H]3C)ncc2c(N)c1F,HPK1,active,0.55,Ki,US2018282282A1（HPK1）,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@H](C)[C@H]3CC#N)ncc2c(N)c1F,HPK1,active,3.7,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(CC(F)(F)F)CC4)ncc2c(N)c1F,HPK1,active,0.168,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cccc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC4)ncc2c(N)c1F,HPK1,active,0.5,Ki,WO2018183964A1(1),Below 1 nM
Cc1cc2[nH]c(=O)oc2cc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC4)ncc2c(N)c1F,HPK1,active,0.038,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(-c2cc3cc(NC(=O)NCC4CC4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.014,Ki,WO2018183964A1(1),Below 1 nM
CC[C@@H]1[C@H](C(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)c(N)c3cn2)[C@H]1c1cnn(C)c1,HPK1,active,0.016,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(-c2cc3cc(NC(=O)[C@@H]4[C@@H](c5cnn(C)c5)[C@H]4C)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(-c2cc3cc(NC(=O)N[C@H](C)c4cnn(C)c4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc2cc(NC(=O)[C@@H]3[C@H](C)[C@H]3CC#N)ncc2c(N)c1F,HPK1,active,1.66,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1c(N)cncc1-c1cc2cc(NC(=O)[C@@H]3[C@@H](C)[C@H]3CC#N)ncc2c(N)c1F,HPK1,active,0.1,Ki,WO2018183964A1(1),Below 1 nM
CC(C)N1CCc2cc(Nc3cc4cc(Cc5ccc[nH]c5=O)c(F)c(N)c4cn3)nn2CC1=O,HPK1,active,9,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1nc(C(=O)N(C)C)ncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)ncc2c(N)c1F,HPK1,active,16.6,Ki,WO2018183964A1(1),10 nM to 100 nM
COc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)ncc2c(N)c1F,HPK1,active,0.035,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3cn4c(n3)CC(=O)N(C)CC4)ncc2c(N)c1F,HPK1,active,16,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CS(=O)(=O)CC4)ncc2c(N)c1F,HPK1,active,0.2,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3ccc4c(n3)CS(=O)(=O)N4C)ncc2c(N)c1F,HPK1,active,1.43,Ki,WO2018183964A1(1),1 nM to 10 nM
CO[C@H]1CC[C@@H](C)c2cc(Nc3cc4cc(-c5cncc(N)c5C)c(F)c(N)c4cn3)nn2C1,HPK1,active,5.8,Ki,WO2018183964A1(1),1 nM to 10 nM
CO[C@H]1CC[C@H](C)c2cc(Nc3cc4cc(-c5cncc(N)c5C)c(F)c(N)c4cn3)nn2C1,HPK1,active,2.2,Ki,WO2018183964A1(1),1 nM to 10 nM
CCn1nc(C#N)cc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)ncc2c(N)c1F,HPK1,active,8.8,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(CC(C)(C)O)CC4)ncc2c(N)c1F,HPK1,active,0.14,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CS(=O)(=O)N(C)C4)ncc2c(N)c1F,HPK1,active,0.21,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc2cc(NC(=O)[C@@H]3[C@@H](c4cnn(C)c4)C3(C)C)ncc2c(N)c1F,HPK1,active,8.7,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C3CC3)CC4)ncc2c(N)c1F,HPK1,active,0.013,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(CC3CC3)CC4)ncc2c(N)c1F,HPK1,active,0.013,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(O)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC4)ncc2c(N)c1F,HPK1,active,0.24,Ki,WO2018183964A1(1),Below 1 nM
Cc1nn(C)c(C)c1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC43CC3)ncc2c(N)c1F,HPK1,active,0.39,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@@H](C)[C@H]3c3cnn(CC(F)F)c3)ncc2c(N)c1F,HPK1,active,0.58,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@H](C)[C@H]3c3cnn(CC(F)F)c3)ncc2c(N)c1F,HPK1,active,2.8,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3[C@@H](C)[C@@H]3c3cnn(CC(F)F)c3)ncc2c(N)c1F,HPK1,active,0.02,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@@H](c4cnn(CC(F)F)c4)[C@H]3C)ncc2c(N)c1F,HPK1,active,0.02,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3[C@@H](C)[C@@H]3c3cnn(CCN4CCOCC4)c3)ncc2c(N)c1F,HPK1,active,0.32,Ki,WO2018183964A1(1),Below 1 nM
Cc1cc(-c2ncco2)ncc1-c1cc2cc(NC(=O)[C@H]3[C@@H](C)[C@@H]3c3cnn(C)c3)ncc2c(N)c1F,HPK1,active,0.72,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc2cc(NC(=O)[C@H]3[C@@H](C)[C@@H]3c3cnn(C)c3)ncc2c(N)c1F,HPK1,active,0.026,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@@H](C)[C@H]3c3cnn(CCO)c3)ncc2c(N)c1F,HPK1,active,0.73,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@@H](c4cnn(CCO)c4)[C@H]3C)ncc2c(N)c1F,HPK1,active,0.12,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3CO)cc2c1,HPK1,active,4.1,Ki,US2018282282A1（HPK1）,1 nM to 10 nM
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C3[C@@H](CC#N)[C@H]3C)cc2c1,HPK1,active,0.19,Ki,US2018282282A1（HPK1）,Below 1 nM
CC[C@@H]1[C@@H](C(=O)Nc2cc3cc(-c4cnc5c(c4C)NCCO5)c(F)c(N)c3cn2)[C@@H]1c1cnn(C)c1,HPK1,active,0.016,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(-c2cc3cc(NC(=O)[C@H]4[C@@H](C)[C@@H]4c4cnn(C)c4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.013,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(-c2cc3cc(NC(=O)[C@@H]4[C@H](C)[C@H]4c4cnn(C)c4)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.025,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc2cc(NC(=O)OC3CCOCC3)ncc2c(N)c1F,HPK1,active,0.02,Ki,WO2018183964A1(1),Below 1 nM
COCCOC(=O)Nc1cc2cc(-c3cncc(N)c3C)c(F)c(N)c2cn1,HPK1,active,5.5,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1c(N)cncc1-c1cc2cc(NC(=O)C3CC3)ncc2c(N)c1F,HPK1,active,0.13,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C#N)ncc2c(N)c1F,HPK1,active,1.4,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1c(N)cncc1-c1cc2cc(NC(=O)OCC3CC3)ncc2c(N)c1F,HPK1,active,0.79,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc2cc(NC(=O)OC(C)C)ncc2c(N)c1F,HPK1,active,1.33,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc2cc(Nc3cccc(C4COCCN4)c3)ncc2c(N)c1F,HPK1,active,5.6,Ki,WO2018183964A1(1),1 nM to 10 nM
Nc1c(F)c(-c2c(Cl)cccc2Cl)cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc12,HPK1,active,2.1,Ki,WO2018183964A1(1),1 nM to 10 nM
[2H]C([2H])([2H])N1CCc2cc(Nc3cc4cc(-c5cnccc5C)c(F)c(N)c4cn3)nn2CC1=O,HPK1,active,0.128,Ki,WO2018183964A1(1),Below 1 nM
CC(=O)N1CC=C(c2cc3cc(Nc4cc5n(n4)CC(=O)N(C(C)C)CC5)ncc3c(N)c2F)CC1,HPK1,active,70,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C(C)C)CC5)ncc3c(N)c2F)cnc2c1NCCO2,HPK1,active,0.018,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)NC(C)(C)C4)ncc2c(N)c1F,HPK1,active,0.021,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)C(C)(C)C4)ncc2c(N)c1F,HPK1,active,0.024,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc2cc(NC(=O)[C@H]3[C@@H](C)[C@@H]3CC#N)ncc2c(N)c1F,HPK1,active,1.49,Ki,WO2018183964A1(1),1 nM to 10 nM
CCc1[nH]c(=O)oc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)ncc2c(N)c1F,HPK1,active,0.22,Ki,WO2018183964A1(1),Below 1 nM
CC(C)=Cc1cc2cc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)ncc2c(N)c1F,HPK1,active,86,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1c(N)nn(C)c1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)ncc2c(N)c1F,HPK1,active,1.6,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1nc(OC(C)C)ncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)ncc2c(N)c1F,HPK1,active,0.796,Ki,WO2018183964A1(1),Below 1 nM
CO[C@@H]1CC[C@H](C)c2cc(Nc3cc4cc(-c5cncc(N)c5C)c(F)c(N)c4cn3)nn2C1,HPK1,active,9.9,Ki,WO2018183964A1(1),1 nM to 10 nM
CC(C)N1CCc2cc(Nc3cc4cc(-c5cncc6c5CC[C@H]6O)c(F)c(N)c4cn3)nn2CC1=O,HPK1,active,5.1,Ki,WO2018183964A1(1),1 nM to 10 nM
CC(C)N1CCc2cc(Nc3cc4cc(-c5cncc6c5CC[C@@H]6O)c(F)c(N)c4cn3)nn2CC1=O,HPK1,active,0.15,Ki,WO2018183964A1(1),Below 1 nM
CC[C@H]1[C@@H](C(=O)Nc2cc3cc(-c4cncc(N)c4C)c(F)c(N)c3cn2)[C@@H]1c1cnn(C)c1,HPK1,active,0.026,Ki,WO2018183964A1(1),Below 1 nM
CCCC1[C@@H](C(=O)Nc2cc3cc(-c4cncc(N)c4C)c(F)c(N)c3cn2)[C@@H]1c1cnn(C)c1,HPK1,active,8.5,Ki,US2018282282A1（HPK1）,1 nM to 10 nM
CC(C)N1CCc2cc(Nc3cc4cc(-c5cncc6c5OCCN6)c(F)c(N)c4cn3)nn2CC1=O,HPK1,active,1.1,Ki,WO2018183964A1(1),1 nM to 10 nM
CC1COC(=O)N1c1cc(N)c2cnc(Nc3cc4n(n3)CC(=O)N(C)CC4)cc2c1,HPK1,active,2,Ki,WO2018183964A1(1),1 nM to 10 nM
CCC1c2cc(Nc3cc4cc(-c5cncc(N)c5C)c(F)c(N)c4cn3)nn2CS1(=O)=O,HPK1,active,0.27,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(CO)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)ncc2c(N)c1F,HPK1,active,0.13,Ki,WO2018183964A1(1),Below 1 nM
COCCN1CCc2cc(Nc3cc4cc(-c5cncc(N)c5C)c(F)c(N)c4cn3)nn2CC1=O,HPK1,active,0.013,Ki,WO2018183964A1(1),Below 1 nM
CN1CCc2cc(Nc3cc4cc(-c5cnn6c5CNCC6)c(F)c(N)c4cn3)nn2CC1=O,HPK1,active,15,Ki,WO2018183964A1(1),10 nM to 100 nM
COc1ncc(-c2cc3cc(NC(=O)[C@H]4[C@@H](C)[C@@H]4c4cnn(C)c4)ncc3c(N)c2F)c(C)c1N,HPK1,active,23,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(CC(F)F)CC5)ncc3c(N)c2F)ccnc1N,HPK1,active,0.87,Ki,WO2018183964A1(1),Below 1 nM
CN1CCc2cc(Nc3cc4cc(-c5cncc(N)c5Cl)c(F)c(N)c4cn3)nn2CC1=O,HPK1,active,0.013,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(-c2cc3cc(Nc4cc5n(n4)CC(=O)N(C)CC5)ncc3c(N)c2F)ccc2c1NCCO2,HPK1,active,0.084,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)C[C@H]4F)ncc2c(N)c1F,HPK1,active,0.017,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)C[C@@H]4F)ncc2c(N)c1F,HPK1,active,0.013,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC4(C)O)ncc2c(N)c1F,HPK1,active,0.154,Ki,WO2018183964A1(1),Below 1 nM
COCC1(O)CN(C)C(=O)Cn2nc(Nc3cc4cc(-c5cnccc5C)c(F)c(N)c4cn3)cc21,HPK1,active,0.15,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC43CC3)ncc2c(N)c1F,HPK1,active,0.013,Ki,WO2018183964A1(1),Below 1 nM
C=C1CN(C)C(=O)Cn2nc(Nc3cc4cc(-c5cnccc5C)c(F)c(N)c4cn3)cc21,HPK1,active,0.043,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@H](C)[C@H]3c3cnc[nH]3)ncc2c(N)c1F,HPK1,active,10.4,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@@H](C)[C@H]3c3cnc[nH]3)ncc2c(N)c1F,HPK1,active,42,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3[C@@H](CO)[C@@H]3c3cnn(C)c3)ncc2c(N)c1F,HPK1,active,7.5,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@@H](C)[C@H]3c3ccn[nH]3)ncc2c(N)c1F,HPK1,active,37.9,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@@H]3CN(C)C)ncc2c(N)c1F,HPK1,active,2.1,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@@H](C)[C@H]3c3cnn(CCN4CCOCC4)c3)ncc2c(N)c1F,HPK1,active,2.9,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1cc(-c2ncco2)ncc1-c1cc2cc(NC(=O)[C@@H]3[C@@H](C)[C@H]3c3cnn(C)c3)ncc2c(N)c1F,HPK1,active,2.4,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)ncc2c(N)c1F,HPK1,active,1.3,Ki,US2018282282A1（HPK1）,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)C[C@@H]4C)ncc2c(N)c1F,HPK1,active,0.033,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3ccn[nH]3)ncc2c(N)c1F,HPK1,active,0.13,Ki,US2018282282A1（HPK1）,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@H]3c3ccn[nH]3)ncc2c(N)c1F,HPK1,active,5.9,Ki,US2018282282A1（HPK1）,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3[C@@H](C)[C@@H]3c3cnn(CCO)c3)ncc2c(N)c1F,HPK1,active,0.082,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3[C@H]4[C@H](O)CCC[C@H]43)ncc2c(N)c1F,HPK1,active,0.87,Ki,US2018282282A1（HPK1）,Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@H]4CCC[C@@H](O)[C@H]43)ncc2c(N)c1F,HPK1,active,95,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@H]4CCC[C@H](O)[C@H]43)ncc2c(N)c1F,HPK1,active,0.95,Ki,WO2018183964A1(1),Below 1 nM
CC[C@@H]1[C@H](C(=O)Nc2cc3cc(-c4cncc(N)c4C)c(F)c(N)c3cn2)[C@@H]1c1cncn1C,HPK1,active,0.33,Ki,US2018282282A1（HPK1）,Below 1 nM
CC[C@H]1[C@H](C(=O)Nc2cc3cc(-c4cncc(N)c4C)c(F)c(N)c3cn2)[C@H]1c1cncn1C,HPK1,active,0.39,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@@H](c4cnn(CCN5CC(O)C5)c4)[C@H]3C)ncc2c(N)c1F,HPK1,active,0.21,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3[C@@H](C)[C@@H]3c3cnn(CCN4CC(O)C4)c3)ncc2c(N)c1F,HPK1,active,0.15,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@@H](C)[C@H]3c3cnn(CCN4CC(O)C4)c3)ncc2c(N)c1F,HPK1,active,2.7,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@@H](C)[C@H]3CC#N)ncc2c(N)c1F,HPK1,active,0.17,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3[C@@H](C)[C@@H]3CC#N)ncc2c(N)c1F,HPK1,active,8.3,Ki,WO2018183964A1(1),1 nM to 10 nM
Cc1c(N)cccc1-c1cc2cc(Nc3cc4n(n3)CC(=O)N(C)CC4O)ncc2c(N)c1F,HPK1,active,1.4,Ki,WO2018183964A1(1),1 nM to 10 nM
CC[C@H](C)n1cnnc1-c1cccc(N2Cc3c(CNC)cc(OC)cc3C2=O)n1,HPK1,active,1,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CNCc1cc(OC)cc2c1CN(c1cccc(-c3nncn3[C@@H](C)C3CC3)n1)C2=O,HPK1,active,0.2,Ki,WO2021224818A1（HPK1）,Below 1 nM
CCCn1cnnc1-c1cccc(N2Cc3c(CNC)cc(OC)cc3C2=O)n1,HPK1,active,5,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
COc1cc(CN)c2c(c1)C(=O)N(c1cccc(-c3nncn3[C@@H](C)CC(F)(F)F)n1)C2,HPK1,active,0.3,Ki,WO2021224818A1（HPK1）,Below 1 nM
CNCc1cc(C(C)(C)C)cc2c1CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,1,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CC[C@H](C)n1cnnc1-c1cccc(N2Cc3c(CNC)cc(N(C)C)cc3C2=O)n1,HPK1,active,0.4,Ki,WO2021224818A1（HPK1）,Below 1 nM
COc1cc2c(c(S(N)(=O)=O)c1)CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,0.4,Ki,WO2021224818A1（HPK1）,Below 1 nM
CNCc1cc([C@@H]2CCOC2)cc2c1CN(c1cccc(-c3nncn3[C@@H](C)CC(F)(F)F)n1)C2=O,HPK1,active,0.05,Ki,WO2021224818A1（HPK1）,Below 1 nM
CNCc1cc(COC)cc2c1CN(c1cccc(-c3nncn3[C@@H](C)CC(F)(F)F)n1)C2=O,HPK1,active,1,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CC[C@H](C)n1cnnc1-c1cccc(N2Cc3c(CNC)cccc3C2=O)n1,HPK1,active,4,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CC[C@H](C)n1cnnc1-c1cccc(N2Cc3c(ccc(OC)c3CN)C2=O)n1,HPK1,active,14,Ki,WO2021224818A1（HPK1）,10 nM to 100 nM
CCNCc1cc(OC)cc2c1CN(c1cccc(-c3nncn3[C@@H](C)CC)n1)C2=O,HPK1,active,18,Ki,WO2021224818A1（HPK1）,10 nM to 100 nM
CCNCc1cc(OC)cc2c1CN(c1cccc(-c3nncn3[C@H](CC)CO)n1)C2=O,HPK1,active,8,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CC[C@H](C)N1C=NN=C1C1=NC(N2CC3=C(C=C(OC)C=C3CO)C2=O)=CC=C1,HPK1,active,5,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CC[C@H](C)N1C=NN=C1C1=NC(N2CC3=C(C=C(OC)C=C3CNCCOC)C2=O)=CC=C1,HPK1,active,20,Ki,WO2021224818A1（HPK1）,10 nM to 100 nM
CC[C@H](C)n1cnnc1-c1cccc(N2Cc3c(CNCCO)cc(OC)cc3C2=O)n1,HPK1,active,5,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CC[C@H](C)n1cnnc1-c1cccc(N2Cc3c(CNC)cc(OC(C)C)cc3C2=O)n1,HPK1,active,2,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CCOc1cc(CNC)c2c(c1)C(=O)N(c1cccc(-c3nncn3[C@@H](C)CC)n1)C2,HPK1,active,1,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CC[C@H](C)n1cnnc1-c1cccc(N2Cc3c(C[C@H](C)O)cc(OC)cc3C2=O)n1,HPK1,active,22,Ki,WO2021224818A1（HPK1）,10 nM to 100 nM
CC[C@H](CO)n1cnnc1-c1cccc(N2Cc3c(CNC)cc(Cl)cc3C2=O)n1,HPK1,active,14,Ki,WO2021224818A1（HPK1）,10 nM to 100 nM
CC[C@H](C)n1cnnc1-c1cccc(N2Cc3c(CN)cc(OC)cc3C2=O)n1,HPK1,active,1,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CNCc1cc(OC(C)C)cc2c1CN(c1cccc(-c3nncn3[C@@H](C)CC(F)(F)F)n1)C2=O,HPK1,active,1,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CC(C)Oc1cc(CN)c2c(c1)C(=O)N(c1cccc(-c3nncn3[C@@H](C)CC(F)(F)F)n1)C2,HPK1,active,1,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CNCc1cc(OC)cc2c1CN(c1cccc(-c3nncn3[C@H](C)C3CC3)n1)C2=O,HPK1,active,7,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CCC(CC)n1cnnc1-c1cccc(N2Cc3c(CNC)cc(OC)cc3C2=O)n1,HPK1,active,1,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CCOc1cc(CN)c2c(c1)C(=O)N(c1cccc(-c3nncn3[C@@H](C)CC(F)(F)F)n1)C2,HPK1,active,0.5,Ki,WO2021224818A1（HPK1）,Below 1 nM
CCOc1cc(CNC)c2c(c1)C(=O)N(c1cccc(-c3nncn3[C@@H](C)CC(F)(F)F)n1)C2,HPK1,active,0.4,Ki,WO2021224818A1（HPK1）,Below 1 nM
CC[C@H](C)n1cnnc1-c1cccc(N2Cc3c(CNC)cc(OC(F)F)cc3C2=O)n1,HPK1,active,4,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CNCc1cc(OC)cc2c1CN(c1cccc(-c3nncn3[C@@H](CO)C3CC3)n1)C2=O,HPK1,active,2,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CC[C@@H](CC(F)(F)F)n1cnnc1-c1cccc(N2Cc3c(CNC)cc(OC)cc3C2=O)n1,HPK1,active,1,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CC[C@H](C)n1cnnc1-c1cccc(N2Cc3c(CN)cc(OC4CC4)cc3C2=O)n1,HPK1,active,4,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
C[C@@H](CC(F)(F)F)n1cnnc1-c1cccc(N2Cc3c(CN)cc(OC(F)F)cc3C2=O)n1,HPK1,active,1,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CC[C@H](C)n1cnnc1-c1cccc(N2Cc3c(CNC)cc(N4CCCC4)cc3C2=O)n1,HPK1,active,0.3,Ki,WO2021224818A1（HPK1）,Below 1 nM
C[C@@H](CC(F)(F)F)n1cnnc1-c1cccc(N2Cc3c(CN)cc(OC4CC4)cc3C2=O)n1,HPK1,active,1,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CNCc1cc(OC2CC2)cc2c1CN(c1cccc(-c3nncn3[C@@H](C)CC(F)(F)F)n1)C2=O,HPK1,active,1,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CC[C@H](C)n1cnnc1-c1cccc(N2Cc3c(CNC)cc(N4CCOCC4)cc3C2=O)n1,HPK1,active,1,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CNCc1cc(S(C)(=O)=O)cc2c1CN(c1cccc(-c3nncn3[C@@H](C)CC(F)(F)F)n1)C2=O,HPK1,active,1,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
COc1ccc2c(c1CN)CN(c1cccc(-c3nncn3[C@@H](C)CC(F)(F)F)n1)C2=O,HPK1,active,3,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CNCc1cc(OC)cc2c1CN(c1cccc(-c3nncn3C3CCCC3)n1)C2=O,HPK1,active,5,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
C[C@@H](CC(F)(F)F)n1cnnc1-c1cccc(N2Cc3c(CN)cc(OCCO)cc3C2=O)n1,HPK1,active,1,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CNCc1cc(-n2cnc(C3CC3)c2)cc2c1CN(c1cccc(-c3nncn3[C@@H](C)CC(F)(F)F)n1)C2=O,HPK1,active,5,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CNCc1cc(OC)cc2c1CN(c1cccc(-c3nncn3[C@H](C(F)F)C3CC3)n1)C2=O,HPK1,active,2,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CNCc1cc(OC)cc2c1CN(c1cccc(-c3nncn3[C@@H](C)[C@@H]3CC3(F)F)n1)C2=O,HPK1,active,0.2,Ki,WO2021224818A1（HPK1）,Below 1 nM
CNCc1cc(OC)cc2c1CN(c1cccc(-c3nncn3[C@@H](C)[C@H]3CC3(F)F)n1)C2=O,HPK1,active,1,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
COc1cc2c(c(S(N)(=O)=O)c1)CN(c1cccc(-c3nncn3[C@H]3CCOC3)n1)C2=O,HPK1,active,2,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CC(C)n1cnnc1-c1cccc(N2Cc3c(cc(OCCN(C)C)cc3S(N)(=O)=O)C2=O)n1,HPK1,active,1,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CNCc1cc(OC)cc2c1CN(c1cccc(-c3cn[nH]c3C(C)C)n1)C2=O,HPK1,active,0.5,Ki,WO2021224818A1（HPK1）,Below 1 nM
CC(C)n1cnnc1-c1cccc(N2Cc3c(cc(OCCO)cc3S(N)(=O)=O)C2=O)n1,HPK1,active,1,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CNCc1cc(C(C)C)cc2c1CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,0.5,Ki,WO2021224818A1（HPK1）,Below 1 nM
CC(C)c1cc(CN)c2c(c1)C(=O)N(c1cccc(-c3nncn3C(C)C)n1)C2,HPK1,active,1,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CNCc1cc(CC#N)cc2c1CN(c1cccc(-c3nncn3[C@@H](C)CC(F)(F)F)n1)C2=O,HPK1,active,0.2,Ki,WO2021224818A1（HPK1）,Below 1 nM
CNCc1cc([C@H](C)O)cc2c1CN(c1cccc(-c3nncn3[C@@H](C)CC(F)(F)F)n1)C2=O,HPK1,active,1,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CNCc1cc([C@@H](C)O)cc2c1CN(c1cccc(-c3nncn3[C@@H](C)CC(F)(F)F)n1)C2=O,HPK1,active,1,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CNCc1cccc2c1CN(c1cccc(-c3cncn3C(C)C)n1)C2=O,HPK1,active,24,Ki,WO2021224818A1（HPK1）,10 nM to 100 nM
CNCc1cc(OC)cc2c1CN(c1cccc(-n3nncc3C(C)C)n1)C2=O,HPK1,active,1,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CCOCc1cc(CNC)c2c(c1)C(=O)N(c1cccc(-c3nncn3[C@@H](C)CC(F)(F)F)n1)C2,HPK1,active,0.33,Ki,WO2021224818A1（HPK1）,Below 1 nM
CNCc1cc(COC(C)C)cc2c1CN(c1cccc(-c3nncn3[C@@H](C)CC(F)(F)F)n1)C2=O,HPK1,active,0.1,Ki,WO2021224818A1（HPK1）,Below 1 nM
CC[C@H]1COC(=O)N1c1cccc(N2Cc3c(CNC)cc(OC)cc3C2=O)n1,HPK1,active,2,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CNCc1cc(OC)cc2c1CN(c1cccc(N3C(=O)OC[C@@H]3C3CC3)n1)C2=O,HPK1,active,3,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CNCc1cc(OC)cc2c1CN(c1cccc(N3C(=O)OC[C@H]3C(F)(F)F)n1)C2=O,HPK1,active,6,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CNCc1cc(C(C)C)cc2c1CN(c1cccc(N3C(=O)OC[C@@H]3C)n1)C2=O,HPK1,active,2,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
CNCc1cc(OC)cc2c1CN(c1cccc(-c3oncc3C(C)C)n1)C2=O,HPK1,active,1,Ki,WO2021224818A1（HPK1）,1 nM to 10 nM
COc1cc2c(cc1Nc1ncc(C(F)(F)F)c(Nc3ccccc3)n1)CN(C)CC2,HPK1,not active,1490,ec50,Merck-Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotheray Tool Compounds, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C)c(Nc3ccccc3)n1)CN(C)CC2,HPK1,medium,780,ec50,Merck-Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotheray Tool Compounds, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C(N)=O)c(Nc3c(C)cccc3Br)n1)CN(C)CC2,HPK1,not active,1770,ec50,Merck-Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotheray Tool Compounds, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C(N)=O)c(Nc3ccccc3C(C)(C)C)n1)CN(C)CC2,HPK1,medium,265,ec50,Merck-Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotheray Tool Compounds, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C(N)=O)c(Nc3ccccc3C)n1)CN(C)CC2,HPK1,medium,322,ec50,Merck-Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotheray Tool Compounds, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C(N)=O)c(Nc3ccccc3Cl)n1)CN(C)CC2,HPK1,medium,252,ec50,Merck-Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotheray Tool Compounds, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C(N)=O)c(Nc3c(F)cccc3CO)n1)CN(C)CC2,HPK1,medium,339,ec50,Merck-Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotheray Tool Compounds, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C(N)=O)c(Nc3ccccc3C3CCCO3)n1)CN(C)CC2,HPK1,medium,386,ec50,Merck-Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotheray Tool Compounds, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C(N)=O)c(Nc3ccccc3C3CCCOC3)n1)CN(C)CC2,HPK1,active,0.069,ic50,Merck-Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotheray Tool Compounds, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C(N)=O)c(Nc3ccccc3N3CCOC3=O)n1)CN(C)CC2,HPK1,medium,274,ec50,Merck-Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotheray Tool Compounds, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(C(N)=O)c(Nc3ccccc3F)n1)CN(C)CC2,HPK1,medium,560,ec50,Merck-Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotheray Tool Compounds, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CC(=O)Nc1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,active,7,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCC(=O)Nc1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,active,3.7,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCOc1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cn1,HPK1,active,4.6,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COCCCN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)nc23)cc1,HPK1,medium,280,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4n3)cc2)CC1,HPK1,medium,211,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)NCCCN6CCCC6)cc5)c4c3)cc2)CC1,HPK1,medium,204,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C6CCCN6)cc5)c4c3)cc2)CC1,HPK1,medium,305,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2nnc(Nc3ccc(CC#N)cn3)cc2c1,HPK1,active,5,ic50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1COC(=O)N1c1cc(N)c2nnc(NC(=O)[C@@H]3C[C@H]3c3cnn(C)c3)cc2c1,HPK1,active,1.9,ic50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc3cc(NC(=O)[C@H]4C[C@@H]4c4cnn(C)c4)nnc3c(N)c2F)cnc2c1NCC(C)O2,HPK1,active,0.82,ic50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CN(c2ccc3nc(-c4c(N[C@H]5CCCC[C@H]5O)c5ccsc5[nH]c4=O)[nH]c3c2)C[C@@H](C)O1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
Nc1c(-c2nc3cc(C(=O)N4CCOCC4)ccc3[nH]2)c(=O)[nH]c2sccc12,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(C(=O)c2ccc3[nH]c(-c4c(N)c5ccsc5[nH]c4=O)nc3c2)CC1,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
Cc1csc2[nH]c(=O)c(-c3nc4ccc(N5CCN(C)CC5)cc4[nH]3)c(NC3CCCC3)c12,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CCOc1csc2[nH]c(=O)c(-c3nc4ccc(N5CCN(C)CC5)cc4[nH]3)c(N)c12,HPK1,active,50,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN([C@@H](C)c2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OC[C@@H](C)N5)c3)cc2C(F)(F)F)CC1,HPK1,active,50,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(C(C)c2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OC[C@@H](C)N5)c3)cc2C(F)(F)F)CC1,HPK1,active,50,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3cc(N[C@H](CO)C4CC4)c(-c4nc(C5CC5)no4)cn3)cc21,HPK1,medium,250,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3cc(N[C@H](CO)c4ccccc4)c(-c4nc(C5CC5)no4)cn3)cc21,HPK1,medium,250,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)c1cnc(Nc2ccc3c(c2)C(C)(C)OC3=O)nc1NCCC(C)(C)N,HPK1,medium,250,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(-c4nc(C5CC5)no4)c(Nc4ccc5[nH]ncc5c4)n3)cc21,HPK1,medium,250,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
Cc1noc(-c2cnc(Nc3ccc4c(c3)C(C)(C)OC4=O)nc2Nc2ccc3[nH]ncc3c2)n1,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)c1ccccc1CNc1nc(Nc2ccc3c(c2)C(C)(C)OC3=O)ncc1-c1nc(C2CC2)no1,HPK1,medium,250,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
Cc1noc(-c2cnc(Nc3ccc4c(c3)C(C)(C)OC4=O)nc2NCc2ccccc2C(C)(C)O)n1,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(-c4nnc(C5(OC(=O)N6CC(F)(F)C6)CC5)o4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,medium,250,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(-c4nnc(-c5ccccn5)o4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,medium,250,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(C(=O)NNC(=O)C(C)(O)C(F)(F)F)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,medium,250,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)C(=O)NNC(=O)c1cnc(Nc2ccc3c(c2)C(C)(C)OC3=O)nc1N[C@H](CO)c1ccccc1,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(-c4nc(-c5cccc(F)c5)no4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,active,50,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(C(=O)N[C@H]4C[C@@H]4c4ccccc4)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,medium,250,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccccc1CNC(=O)c1cnc(Nc2ccc3c(c2)C(C)(C)OC3=O)nc1N[C@H](CO)c1ccccc1,HPK1,medium,250,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
CC(NC(=O)c1cnc(Nc2ccc3c(c2)C(C)(C)OC3=O)nc1N[C@H](CO)c1ccccc1)c1ccccc1,HPK1,medium,250,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)nc23)cc1,HPK1,medium,228,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC6(COC6)C5)cc4)c3n2)cc2c1CN(C)CC2,HPK1,active,17,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@@H](C)O)cc4)c3n2)cc2c1CN(C)CC2,HPK1,active,11,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@H](C)O)cc4)c3n2)cc2c1CN(C)CC2,HPK1,active,12,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1[C@H](C(=O)Nc2cc3cc(N4C(=O)OC[C@@H]4C)cc(N)c3nn2)[C@H]1c1cnn(C)c1,HPK1,medium,183,ec50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1COC(=O)N1c1cc(N)c2nnc(NC(=O)[C@@H]3[C@H](C)[C@H]3c3cnn(C)c3)cc2c1,HPK1,medium,438,ec50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(N)c3nnc(NC(=O)[C@H]4C[C@@H]4c4cnn(CCO)c4)cc3c2)cnc2c1NCCO2,HPK1,medium,222,ec50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1cc([C@H]2C[C@@H]2C(=O)Nc2cc3cc(N4C(=O)OC[C@@H]4CF)cc(N)c3nn2)cn1,HPK1,medium,339,ec50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1COC(=O)N1c1cc(N)c2nnc(NC(=O)[C@H]3C[C@@H]3c3cnn(C4CC4)c3)cc2c1,HPK1,medium,376,ec50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1cc([C@H]2C[C@@H]2C(=O)Nc2cc3cc(N4C(=O)OC[C@@H]4C)cc(N)c3nn2)cn1,HPK1,medium,384,ec50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
CCn1cc([C@H]2C[C@@H]2C(=O)Nc2cc3cc(N4C(=O)OC[C@@H]4C)cc(N)c3nn2)cn1,HPK1,medium,544,ec50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1[C@@H](C(=O)Nc2cc3cc(N4C(=O)OC[C@@H]4C)cc(N)c3nn2)[C@@H]1c1cnn(C)c1,HPK1,medium,375,ec50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2nnc(Nc3ccc4c(n3)CCN(S(C)(=O)=O)C4)cc2c1,HPK1,active,28,ic50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N1CCc2nc(Nc3cc4cc(-c5cnccc5C)cc(N)c4nn3)ccc2C1,HPK1,active,12,ic50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc2cc(Nc3ccc4c(n3)CCN(S(C)(=O)=O)C4)nnc2c(N)c1F,HPK1,active,28,ic50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
COC1CCN(c2ccc(Nc3cnc(-c4cnc5c(F)cccn45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1cc2ncc(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)c-2cn1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnn4c3CCCC4)ccc(Nc3ccc(N4CCC[C@]5(CCNC5=O)C4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1cc2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cnc-2cn1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3ncc4cnccn34)ccc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4cccc(C5CCNCC5)n4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)Cc1ccn2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cnc2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3cnn(C4CCOCC4)c3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(CN5CC(F)C5)ccn34)ccc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3ccc(S(=O)(=O)CC4COC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cncc4nccn34)ncc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cccn4nccc34)ncc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3cccc(O[C@@H]4CCC[C@@H]4O)n3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnn4c3CCCC4)ncc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cnccn34)ccc(Nc3ccc(S(=O)(=O)N4CCC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CCn2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cnc2C1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4n3CCCC4)ccc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4n3CCCCC4)ccc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnn4c3CCCCC4)ccc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4ccnc5ocnc45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3cnc(-c4cnc5n4CCC5)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1COc2c(-c3ccc(Nc4ccc(N5CCN(C)CC5)cn4)c4c3CNC4=O)cnn2C1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2ccnc3c2ccn3Cc2ccccc2)ccc(Nc2ccc(N3CCN(C)CC3)cn2)c1C(N)=O,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3cnc(-c4cnn5c4CCC5)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3cnc(-c4cccc5[nH]ccc45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3cnc(-c4c[nH]c5cc(O)ccc45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCOc1ccn2c(-c3ccc(Nc4ccc(N5CCC(F)C(O)C5)cn4)c4c3CNC4=O)cnc2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4cccc(N5CCCNCC5)n4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN[C@H]1CCCN(c2cccc(Nc3cnc(-c4ccnc5c4ccn5C)c4c3C(=O)NC4)n2)C1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(-c3ncc(Nc4ccc(N5CCC[C@H](C(C)(C)O)C5)cn4)c4c3CNC4=O)ccnc2n1C,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2cccc(Nc3ccc(-c4cnc5cnccn45)c4c3C(=O)NC4)n2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CNC1CCN(c2cccc(Nc3cnc(-c4ccnc5c4ccn5C)c4c3C(=O)NC4)n2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)[C@@H]1CCCN(c2ccc(Nc3cnc(-c4cnc5cc(F)ccn45)c4c3C(=O)NC4)nc2)C1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cnc2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cccn12,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cnccn34)ncc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)c1ccn2c(-c3ccc(Nc4ccc(N5CCOCC5)cn4)c4c3CNC4=O)cnc2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
COCCNc1ccn2c(-c3ccc(Nc4ccc(N5CCOCC5)cn4)c4c3CNC4=O)cnc2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
COCCNc1ccn2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cnc2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(C3=CNC4C=CC=NN34)ncc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1ccn2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cnc2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
C/C=C\n1c(-c2ncc(Nc3ccc(N4CCOCC4)cn3)c3c2CNC3=O)cnc1C,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
N#Cc1ccn2c(-c3ncc(Nc4ccc(N5CCOCC5)cn4)c4c3CNC4=O)cnc2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOc1c(C#N)ccn2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cnc12,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ncc2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cccn12,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccn2c(-c3ncc(Nc4ccc(N5CCOCC5)cn4)c4c3CNC4=O)cnc2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnn4c3CCC(C(=O)NC3CC3)C4)ccc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4cccc(N5CCC(O)CC5)n4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCCc2c(-c3ccc(Nc4ccc(N5CCNCC5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2ccc(Nc3ccc(N4CCNCC4)cn3)c3c2CNC3=O)c2ccn(C)c2n1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cnc2c(ccn2C)c1-c1ccc(Nc2ccc(N3CCNCC3)cn2)c2c1CNC2=O,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cnc2[nH]ccc2c1-c1ccc(Nc2ccc(N3CCN(C)CC3)cn2)c2c1CNC2=O,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2ccc(Nc3ccc(N4CCN(C)CC4)cn3)c3c2CNC3=O)c2cc[nH]c2n1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4ccnc5ccn(C)c45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4ccnc5c4cnn5C)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1nc2ccccn2c1-c1ccc(Nc2ccc(N3CCN(C)CC3)cn2)c2c1CNC2=O,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)n1ccc2c(-c3ccc(Nc4ccc(N5CCN(C)CC5)cn4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4cnc5c(ccn5C)c4)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4ccn5ncnc5c4)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4ccn5ccnc5c4)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cnc2[nH]cc(-c3ccc(Nc4ccc(N5CCN(C)CC5)cn4)c4c3CNC4=O)c2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4c[nH]c5cccnc45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4cccc5nccn45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ncccc2c1-c1ccc(Nc2ccc(N3CCN(C)CC3)cn2)c2c1CNC2=O,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc2c(-c3ccc(Nc4ccc(N5CCN(C)CC5)cn4)c4c3CNC4=O)c[nH]c2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3ccc(-c4cn(C)c5ncccc45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ncccc2c1-c1ncc(Nc2ccc(N3CCN(C)CC3)cn2)c2c1CNC2=O,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc2[nH]cc(-c3ncc(Nc4ccc(N5CCN(C)CC5)cn4)c4c3CNC4=O)c2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3cnc(-c4c[nH]c5ccncc45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc2c(-c3ncc(Nc4ccc(N5CCN(C)CC5)cn4)c4c3CNC4=O)c[nH]c2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ccccc2c1-c1ncc(Nc2ccc(N3CCN(C)CC3)cn2)c2c1CNC2=O,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2c(-c3ncc(Nc4ccc(N5CCN(C)CC5)cn4)c4c3CNC4=O)c[nH]c12,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cccc2c(-c3ncc(Nc4ccc(N5CCN(C)CC5)cn4)c4c3CNC4=O)c[nH]c12,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3c[nH]c4ccccc34)ncc(Nc3ccc(N4CCOCC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3cnc(-c4c[nH]c5ccccc45)c4c3C(=O)NC4)nc2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3c[nH]c4ccccc34)ncc(Nc3ccc(N4CCNCC4)cn3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc2c(-c3ncc(Nc4ccc(N5CCN(C)CC5)cn4)c4c3CNC4=O)c[nH]c2c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1Nc2ccc(-c3ccc(F)cc3F)cc2C1=Cc1ccc(N2CCN(C3COC3)CC2)nc1,HPK1,medium,500,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1ccc2c(c1)/C(=C\c1cn(C3CCN(C)CC3)nn1)C(=O)N2,HPK1,medium,500,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1ccc2c(c1)/C(=C\c1ccc(-c3cnn(C)c3)nc1)C(=O)N2,HPK1,medium,100.01,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1ccc2c(c1)C(=Cc1ccc(-c3cn[nH]c3)nc1)C(=O)N2,HPK1,medium,100.01,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1ccc2c(c1)C(=Cc1ccc(C(=O)N3CCNCC3)cc1)C(=O)N2,HPK1,medium,500,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1ccc2c(c1)C(=Cc1ccc(CN3CCN(C)CC3)cc1)C(=O)N2,HPK1,medium,100.01,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1ccc2c(c1)/C(=C\C1=CN(C3CCNCC3)NN1)C(=O)N2,HPK1,medium,100.01,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc4c3OCCN4)cc2)n(-c2ccc(C#N)cc2)n1,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1CNc2ncnc(Oc3cc(C(=O)Nc4cc(N5CCN(C)CC5)cc(C(F)(F)F)c4)ccc3Cl)c2O1,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)COc2c(ncnc2Oc2ccc(NC(=O)Nc3cc(C(C)(C)C)nn3-c3cccc(C#N)c3)cc2)N1,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1nc(C(C)(C)C)cc1NC(=O)Nc1ccc(Cl)c(Oc2ncnc3c2OCC(C)(C)N3)c1,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1COc2c(ncnc2Oc2cc(C(=O)Nc3cc(C(C)(C)C)on3)ccc2Cl)N1,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(Oc4ncnc5c4OCC(C)(C)N5)c3)cc2C(F)(F)F)CC1,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)COc2c(ncnc2Oc2ccc(NC(=O)Nc3cc(C(C)(C)C)on3)cc2Cl)N1,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)COc2c(ncnc2Oc2cc(C(=O)N/C(=C/C(=N)C(C)(C)C)Nc3cccc(C#N)c3)ccc2Cl)N1,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)Nc2cc(C(C)(C)C)on2)cc1Oc1ccnc2c1OCCN2,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc4c3OCCN4)cc2)no1,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1COc2c(ncnc2Oc2ccc(NC(=O)Nc3cc(C(C)(C)C)on3)cc2Cl)N1,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4ccnc5c4OCCN5)c3)cc2C(F)(F)F)CC1,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OC[C@H](CO)N5)c3)cc2C(F)(F)F)CC1,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc2C(F)(F)F)CC1,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)Nc2cc(N3CCN(C4COC4)CC3)cc(C(F)(F)F)c2)cc1Oc1ccnc2c1OCCN2,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4ncnc5c4OCCN5)c(C)c3)cc2C(F)(F)F)CC1,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4ncnc5c4OCCN5)cc3)cc2C(F)(F)F)CC1,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1COc2c(ncnc2Oc2cc(C(=O)Nc3cc(N4CCN(C)CC4)cc(C(F)(F)F)c3)ccc2Cl)N1,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4O[C@H](C)CN5)c3)cc2C(F)(F)F)CC1,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1COc2c(ncnc2Oc2cc(C(=O)Nc3cc(N4CCN(C)CC4)cc(C(F)(F)F)c3)ccc2Cl)N1,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1COc2c(ncnc2Oc2cc(C(=O)Nc3cc(N4CCN(C)CC4)cc(C(F)(F)F)c3)ccc2Cl)N1,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4CCCN5)c3)cc2C(F)(F)F)CC1,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(Oc4ccnc5c4OCC(=O)N5)c3)cc2C(F)(F)F)CC1,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCC(Oc2ccc(NC(=O)c3ccc(C)c(Oc4ccnc5c4OCCN5)c3)cc2C(F)(F)F)CC1,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(Oc4ccnc5c4OCCN5)c3)cc2C(F)(F)F)CC1,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(Oc4ncnc5c4O[C@@H](C)CN5)c3)cc2C(F)(F)F)CC1,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)Nc2cc(N3CCN(C)CC3)cc(C(F)(F)F)c2)cc1Oc1ncnc2c1OCCN2,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2cc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCC(C)(C)N5)c3)cc(C(F)(F)F)c2)CC1,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc2C(F)(F)F)CC1,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2cc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc(C(F)(F)F)c2)CC1,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)N1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc2C(F)(F)F)CC1,HPK1,medium,100,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OC(=O)c2ccc(Nc3ncc(C(=O)O)c(N[C@H](CO)c4ccccc4)n3)cc21,HPK1,medium,250,ic50,WO2019090198A1_Original_document_20201120095019, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc5c(c4)NCCO5)c3c2)ccc1N1CCN(C)CC1,HPK1,medium,117,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccnc(C(=O)N(C)C)n4)c3c2)ccc1N1CCN(C)CC1,HPK1,medium,142,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC2(CC1)CN(c1ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc1)C2,HPK1,medium,173,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2C(F)(F)F)CC1,HPK1,medium,106,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2)C1,HPK1,medium,276,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2OC2COC2)CC1,HPK1,medium,263,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC7(COC7)C6)cc5)c4n3)cc2C#N)CC1,HPK1,medium,105,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)nc2)CC1,HPK1,medium,178,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2OCCN2CCOCC2)CC1,HPK1,medium,470,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC6(COC6)C5)nc4)c3c2)ccc1N1CCN(C)CC1,HPK1,medium,107,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cn2)CC1,HPK1,medium,173,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C5CCOCC5)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,medium,168,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)c(C)c4)cc23)ccc1C(=O)N(C)C,HPK1,medium,135,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4Cl)c3c2)ccc1N1CCN(C)CC1,HPK1,medium,122,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)Nc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,medium,126,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2Cl)cc(C)c1N1CCN(C)CC1,HPK1,medium,275,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2)CC1,HPK1,medium,113,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCC(N(C)C)CC5)cc4)cc23)cc1,HPK1,medium,200,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CN(C)CCN1c1ccc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc1,HPK1,medium,128,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1CN(C)CCN1c1ccc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc1,HPK1,medium,141,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cn4)c3c2)ccc1N1CCN(C)CC1,HPK1,medium,203,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2N2CC[C@H](O)C2)CC1,HPK1,medium,141,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(NC(=O)c2cc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)ccc2N2CCN(C)CC2)cc1,HPK1,medium,197,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4cccc(C(=O)N5CC(N(C)C)C5)c4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,medium,310,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(OC5CCOC5)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,medium,286,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4nc(C(=O)N5CC(N(C)C)C5)co4)c3c2)ccc1N1CCN(C)CC1,HPK1,medium,173,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(-c5ccncc5)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,medium,130,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(-c5cccnc5)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,medium,136,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CC(c1ccc(C(=O)N(C)C)cc1)c1c[nH]c2ncc(-c3ccc(N4CCN(C)CC4)cc3)cc12,HPK1,medium,214,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)CC1,HPK1,medium,127,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(S(=O)(=O)Nc2ccc(-c3c[nH]c4ncc(-c5ccc(N6CCN(C)CC6)cc5)cc34)cc2)cc1,HPK1,medium,108,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccccc1-c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,medium,380,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(Cc5ccc(C(=O)N(C)C)cc5)c4n3)cc2)CC1,HPK1,medium,115,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1CN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4n3)cc2)C[C@@H](C)O1,HPK1,medium,168,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(S(=O)(=O)C6CC6)cc5)c4n3)cc2)CC1,HPK1,medium,122,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)nc23)CC1,HPK1,medium,288,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CC(=O)N(C)c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)nc23)cc1,HPK1,medium,235,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)c1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)ccc1N1CCN(C)CC1,HPK1,medium,256,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccnn5C)c4n3)cc2)CC1,HPK1,medium,197,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(-c6ccnn6C)cc5)c4n3)cc2)CC1,HPK1,medium,345,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(NC(=O)CC6CCCC6)cc5)c4c3)cc2)CC1,HPK1,medium,313,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COC1CN(C(=O)c2ccc(-c3c[nH]c4ncc(-c5ccc(N6CCN(C)CC6)cc5)cc34)cc2)C1,HPK1,medium,300,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(NC(=O)c2ccc(-c3c[nH]c4ncc(-c5ccc(N6CCN(C)CC6)cc5)cc34)cc2)cc1,HPK1,medium,330,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(-c6cnn(C)c6)cc5)c4n3)cc2)CC1,HPK1,medium,300,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C6CNC(=O)C6)cc5)c4c3)cc2)CC1,HPK1,medium,112,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(CCC6COC6)cc5)c4c3)cc2)CC1,HPK1,medium,173,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(N6CCCCC6)cc5)c4c3)cc2)CC1,HPK1,medium,112,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,medium,110,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(OCC6CC6)cc5)c4c3)cc2)CC1,HPK1,medium,110,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(OCc6ccccc6)cc5)c4c3)cc2)CC1,HPK1,medium,140,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)Oc1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,medium,130,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)C#Cc1cccc(COc2cc(-c3cnc(C4CCNCC4)s3)cnc2N)c1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ncc(-c3cnc(N)c(OCc4cccc(C#CC5(O)CCC5)c4)c3)s2)CC1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
C#Cc1cc(COc2cc(-c3cnc(C4CCN(C)CC4)s3)cnc2N)ccn1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
Nc1ncc(-c2cnc(C3CCCCC3)s2)cc1OCc1ccncc1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)C#Cc1ccc(F)c(COc2cc(-c3cnc(C4CCNCC4)s3)cnc2N)c1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)C#Cc1cccc(COc2cc(-c3cnc(C4CCCCC4)s3)cnc2N)c1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)C#Cc1cccc(COc2cc(-c3cnc(N4CCCCC4)s3)cnc2N)c1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ncc(-c3cnc(N)c(OCc4cccc(C#CC5(O)CC5)c4)c3)s2)CC1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CC1CN(c2ncc(-c3cnc(N)c(OCc4cccc(C#CC(C)(C)O)c4)c3)s2)CC(C)N1C,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ncc(-c3cnc(N)c(OCc4cccc(C#CC(C)(C)O)c4)c3)s2)CC1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCCN(c2ncc(-c3cnc(N)c(OCc4cccc(C#CC(C)(C)O)c4)c3)s2)CC1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)C#Cc1cccc(COc2cc(-c3cnc(C4CCOCC4)s3)cnc2N)c1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CC1CN(c2ncc(-c3cnc(N)c(OCc4cccc(C#CC(C)(C)O)c4)c3)s2)CCN1C,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1ncc(-c2cnc(N)c(OCc3cc(C#CC(C)(C)O)ccc3F)c2)s1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ncc(-c3cnc(N)c(OCc4cc(C#CC(C)(C)O)ccc4F)c3)s2)CC1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)C#Cc1cccc(COc2cc(-c3cnc(Oc4ccccc4)s3)cnc2N)c1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
Cc1nc(C2CCN(C)CC2)sc1-c1cnc(N)c(OCc2ccncc2)n1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(n2cc(-c3cnc(N)c(OCc4ccncc4)n3)c(N)n2)CC1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
Nc1ncc(-c2cnc(C3CCOCC3)s2)cc1OCc1ccncc1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ncc(-c3cnc(N)c(OCc4ccncc4)c3)s2)CC1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ncc(-c3cnc(N)c(OCc4ccnc(C#CC(C)(C)O)c4)c3)s2)CC1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
Nc1ncc(-c2cnc(C3CCNCC3)s2)cc1OCc1ccncc1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ncc(-c3cnc(N)c(OCc4cccc(C#CC(C)(C)O)c4)c3)s2)CC1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ncc(-c3cnc(N)c(OCc4ccncc4)c3)s2)CC1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ncc(-c3cnc(N)c(OCc4cccc(C#CCCCCO)c4)c3)s2)CC1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(n2cc(-c3cnc(N)c(OCc4cccc(C#CC(C)(C)O)c4)c3)cn2)CC1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(C)CC5)nc23)ccc1C(=O)N(C)CC(C)(C)O,HPK1,medium,186,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(CCC(=O)N[C@H]4CC[C@H](O)CC4)CC5)nc23)ccc1C(=O)N(C)C,HPK1,medium,122,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(CCN4CCOCC4)CC5)nc23)ccc1C(=O)N(C)C[C@@H]1CCOC1,HPK1,medium,137,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C1CCN(C)CC1)n1c(=O)[nH]c2cc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)ccc21,HPK1,medium,105,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CC(C1CCN(C)CC1)n1ncc2cc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)ccc21,HPK1,medium,117,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(n2cnc3cc(-c4cnc5[nH]cc(-c6ccc(C(=O)N(C)C)cc6)c5c4)ccc32)CC1,HPK1,medium,118,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(CN2N=CC3C=C(c4cnc5[nH]cc(-c6ccc(C(=O)N(C)C)cc6)c5c4)C=CC32)CC1,HPK1,medium,202,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(Cn2cc3cc(-c4cnc5[nH]cc(-c6ccc(C(=O)N(C)C)cc6)c5c4)ccc3n2)CC1,HPK1,medium,106,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(C2N=NC3C(c4cnc5[nH]cc(-c6ccc(C(=O)N(C)C)cc6)c5c4)=CC=CC32)CC1,HPK1,medium,306,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc5c(c4)CCN(CCO)C5)cc23)cc1,HPK1,medium,115,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCc2cc(-c3cnc4[nH]cc(-c5ccc(C(=O)N6CC7(COC7)C6)cc5)c4c3)ccc2C1,HPK1,medium,125,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc5c(c4)CCNC5)cc23)cc1,HPK1,medium,160,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCOc2cc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)ccc2C1,HPK1,medium,119,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc5c(c4)CNCC5)cc23)cc1,HPK1,medium,107,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(C#CC(C)(C)O)cc(COc2cc(-c3cnc(C4CCN(C)CC4)s3)cnc2N)c1,HPK1,not active,1000,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
C=CC(C)(O)C#Cc1cccc(COc2cc(-c3cnc(C4CCN(C)CC4)s3)cnc2N)c1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CC1CN(C)CCC1c1ncc(-c2cnc(N)c(OCc3cccc(C#CC(C)(C)O)c3)c2)s1,HPK1,medium,100,ic50,WO2019206049A1_Original_document_20201120093115, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ncc(-c3cnc(N)c(OCc4cccc(C#CC5(O)CCCCC5=O)c4)c3)s2)CC1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C#CC(C)(C)O)cc1COc1cc(-c2cnc(C3CCN(C)CC3)s2)cnc1N,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(C#CC(C)(C)O)cc1COc1cc(-c2cnc(C3CCN(C)CC3)s2)cnc1N,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ccnc(-c3cnc(N)c(OCc4cccc(C#CC(C)(C)O)c4)c3)c2)CC1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)C#Cc1cccc(COc2cc(-c3cnc(C4CCCNC4)s3)cnc2N)c1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ncc(-c3cnc(N)c(OCc4cc(C#CC(C)(C)O)ccc4Cl)c3)s2)CC1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
Nc1ncc(-c2cnn(C3CCNCC3)c2)cc1OCc1cccc(C#CC2(O)CC2)c1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
Nc1ncc(-c2cnc(C3CCNCC3)s2)cc1OCc1cc(C#CC2(O)CC2)ccc1F,HPK1,medium,100,ic50,WO2019206049A1_Original_document_20201120093115, not Ki or Kd; not used in NCI fingerprint analysis
Nc1ncc(-c2cnc(C3CCNCC3)s2)cc1OCc1cccc(C#CC2(O)CC2)c1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
Nc1ncc(-c2cnn(C3CCOCC3)c2)cc1OCc1cc(C#CC2(O)CC2)ccc1F,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
Nc1ncc(-c2cnc(C3CCOCC3)s2)cc1OCc1cccc(C#CC2(O)CC2)c1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)C#Cc1cccc(COc2cc(-c3cnc(C4CCCCN4)s3)cnc2N)c1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
Nc1ncc(-c2cnn(C3CCOCC3)c2)cc1OCc1cccc(C#CC2(O)CC2)c1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ncc(-c3cnc(N)c(OCc4cccc(C#CC5(O)CCCC5)c4)c3)s2)CC1,HPK1,medium,100,ic50,WO2019206049A1_Original_document_20201120093115, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ncc(-c3cnc(N)c(OCc4cc(F)cc(C#CC(C)(C)O)c4)c3)s2)CC1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ncc(-c3cnc(N)c(OCc4cc(C#CC5(O)CC5)ccc4F)c3)s2)CC1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
Nc1ncc(-c2cnc(C3CCOCC3)s2)cc1OCc1cc(C#CC2(O)CC2)ccc1F,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
Cc1nc(C2CCN(C)CC2)sc1-c1cnc(N)c(OCc2cccc(C#CC(C)(C)O)c2)c1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
Nc1ncc(C2CN=C(C3CCCCC3)S2)cc1OCc1ccncc1,HPK1,medium,100,ic50,WO2019206049A1_Original_document_20201120093115, not Ki or Kd; not used in NCI fingerprint analysis
CC1=CC(c2cnc3[nH]cc(-c4ccc(C(=O)N(C)CC(C)(C)O)c(C)c4)c3n2)=CC2CC[C@@H]3CN(C)CCN3C12,HPK1,medium,101,ic50,WO_2021013083_A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c[nH]c2ncc(-c3ccc(CF)c(P(C)(C)=O)c3)cc12,HPK1,medium,500,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c[nH]c2ncc(-c3ccc(CO)c(P(C)(C)=O)c3)cc12,HPK1,medium,500,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c[nH]c2ncc(-c3ccc(C(=O)OC)c(P(C)(C)=O)c3)cc12,HPK1,medium,500,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c[nH]c2ncc(-c3ccc(NC)c(P(C)(C)=O)c3)cc12,HPK1,medium,500,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c[nH]c2ncc(-c3ccc(C(N)=O)c(P(C)(C)=O)c3)cc12,HPK1,medium,500,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c[nH]c2ncc(-c3ccc(N4CCCC4=O)c(P(C)(C)=O)c3)cc12,HPK1,medium,500,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c[nH]c2ncc(-c3ccc(-c4ncco4)c(P(C)(C)=O)c3)cc12,HPK1,medium,500,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c[nH]c2ncc(-c3ccc(C(F)F)c(P(C)(C)=O)c3)cc12,HPK1,medium,500,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c[nH]c2ncc(-c3ccc(N4CCCC4)c(P(C)(C)=O)c3)cc12,HPK1,medium,500,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c[nH]c2ncc(-c3ccc(OC)c(P(C)(C)=O)c3)cc12,HPK1,medium,500,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c[nH]c2ncc(-c3cccc(P(C)(C)=O)c3)cc12,HPK1,medium,500,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc3ccc(P(C)(C)=O)cc3n1)CN(C)CC2,HPK1,medium,500,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc3c(n1)N(c1ccccc1P(C)(C)=O)CCO3)CN(C)CC2,HPK1,medium,500,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc3c(n1)N(c1ccccc1)CCO3)CN(C)CC2,HPK1,medium,500,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc3c(n1)n(-c1ccccc1)c(=O)n3C)CN(C)CC2,HPK1,medium,500,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc3ccn(-c4ccccc4C(=O)N(C)C)c3n1)CN(C)CC2,HPK1,medium,500,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CCC4(COC4)C3)n1)CN(C)CC2,HPK1,medium,500,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)COC(=O)Cc1cn(-c2nc(Nc3cc4c(cc3OC)CCN(C)C4)ncc2Cl)c2ccccc12,HPK1,medium,500,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-n3cc(C4(O)COC4)c4ccccc43)n1)CN(C)CC2,HPK1,medium,500,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-c3ccnc4ccccc34)n1)CN(C)CC2,HPK1,medium,500,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CCn4c3cccc4=O)n1)CN(C)CC2,HPK1,medium,500,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CCc4cccnc43)n1)CN(C)CC2,HPK1,medium,500,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CCc4c(Cl)cccc43)n1)CN(C)CC2,HPK1,medium,500,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(N3CCc4ccccc4C3)n1)CN(C)CC2,HPK1,medium,500,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1CN(C)CCN1c1ncc(-c2cnc(N)c(OCc3cccc(C#CC(C)(C)O)c3)c2)s1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
NC1=C(OCc2cc(C#CC3(O)CC3)ccc2F)C=C(c2cnc(C3CCNCC3)s2)CN1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)NCCc3ccccc3)cc2c1,HPK1,not active,1000,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3C(C)(C)CN(C(=O)c4cccnc4)CC3(C)C)cc2c1,HPK1,not active,1000,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3C(C)(C)CN(S(=O)(=O)N(C)C)CC3(C)C)cc2c1,HPK1,not active,1000,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3C(C)(C)CN(S(C)(=O)=O)CC3(C)C)cc2c1,HPK1,not active,1000,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C=C3C(C)(C)CN(C(=O)N(C)C)CC3(C)C)cc2c1,HPK1,not active,1000,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)/C=C3/CCNC3)cc2c1,HPK1,not active,1000,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(NC(=O)C(=O)Nc2cc3cc(-c4cnccc4C)cc(N)c3cn2)c(C#N)c1,HPK1,not active,1000,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3ccc(C4CC4)cc3)cc2c1,HPK1,not active,1000,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3ccc(Cl)cc3F)cc2c1,HPK1,not active,1000,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3ccccc3C(C)C)cc2c1,HPK1,not active,1000,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3c(C)cccc3C(C)C)cc2c1,HPK1,not active,1000,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)N3CCn4c(nnc4-c4ccccc4)C3)cc2c1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)N(C)c3cnn(C)c3)cc2c1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NS(=O)(=O)N(C)C)cc2c1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc2cc(NC(=O)C(=O)N(C)C)ncc2c(N)n1,HPK1,medium,100,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(N)cncc1-c1cc(N)c2nnc(Nc3cc4n(n3)CS(=O)(=O)N(C)C4)cc2c1,HPK1,medium,294,ec50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1COC(=O)N1c1cc(N)c2nnc(NC(=O)[C@@H]3[C@@H](c4cnn(C)c4)[C@H]3C)cc2c1,HPK1,medium,769,ec50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1COC(=O)N1c1cc(N)c2nnc(NC(=O)[C@H]3C[C@@H]3C#N)cc2c1,HPK1,medium,228,ec50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2nnc(Nc3ccc(C(=O)N4CCOCC4)cn3)cc2c1,HPK1,medium,260,ec50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(N)c3nnc(NC(=O)[C@H]4C[C@@H]4c4cnn(CCCS(C)(=O)=O)c4)cc3c2)cnc2c1NCCO2,HPK1,not active,1318,ec50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1COC(=O)N1c1cc(N)c2nnc(NC(=O)[C@H]3C[C@@H]3c3cnn(CC(F)(F)F)c3)cc2c1,HPK1,medium,959,ec50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2nnc(NC(=O)N3CC(C#N)C3)cc2c1,HPK1,medium,113,ec50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(-c2cc(N)c3nnc(NC(=O)[C@H]4C[C@@H]4c4cnn(C)c4)cc3c2)cnc2c1NCCS2,HPK1,medium,113,ec50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C#N)cc1-c1cc(N)c2nnc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)cc2c1,HPK1,medium,107,ic50,WO2021004535A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cccc(F)c1-c1cc2c(-c3ccc(N4CCNCC4)cn3)cnc(N)c2cc1C#N,HPK1,active,50,ic50,WO2021175271A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cccc(F)c1-c1cc2c(-c3cccc(N4CCNCC4)n3)cnc(N)c2cc1C#N,HPK1,active,50,ic50,WO2021175271A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
N#Cc1cnc2[nH]cc(-c3ccc(F)cc3)c2c1Oc1c(F)cc(NC2=NCC(F)(CO)CO2)cc1F,HPK1,active,50,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CC1(CN)CN=C(Nc2cc(F)c(Oc3ncnc4[nH]cc(-c5ccc(F)cc5)c34)c(F)c2)OC1,HPK1,active,50,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CNCc1cc(C)c(-c2c[nH]c3ncnc(Oc4c(F)cc(NC5=NCC(F)(CO)CO5)cc4F)c23)c(F)c1,HPK1,active,50,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
COCCCN(C)C(=O)c1ccc(-c2c[nH]c3nnc(-c4cc(C)c(N5CCN(C)CC5)c(C)c4)cc23)cc1,HPK1,medium,500,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
N#Cc1cnc2[nH]cc(-c3ccc(F)cc3)c2c1Oc1ccc(NC2CCCOC2)cc1F,HPK1,medium,500,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(Nc2cc(F)c(Oc3ncnc4[nH]cc(-c5ccc(F)cc5)c34)c(F)c2)CC1,HPK1,active,50,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
N#Cc1cnc2[nH]cc(-c3ccc(F)cc3)c2c1Oc1ccc(NC(=O)C2CCC(O)CC2)cc1F,HPK1,active,50,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
N#Cc1cnc2[nH]cc(-c3ccc(F)cc3)c2c1Oc1ccc(NC2CCOCC2)cc1F,HPK1,medium,500,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Fc1ccc(-c2c[nH]c3ncnc(Oc4c(F)cc(NC5CCC6(CCNC6)CC5)cc4F)c23)cc1,HPK1,active,50,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
OCC1(F)CN=C(Nc2ccc(Oc3c(Cl)cnc4[nH]cc(-c5ccc(F)cc5)c34)c(F)c2)OC1,HPK1,active,50,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Fc1cc(NC2=NCC3(COC3)CO2)cc(F)c1Oc1ncnc2[nH]cc(C3(C(F)(F)F)CC3)c12,HPK1,active,50,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
N#Cc1cnc2[nH]cc(-c3ccc(F)cc3)c2c1Oc1ccc(NC2=NCC3(COC3)CO2)cc1F,HPK1,active,50,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2cc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OC(C)(C)C(=O)N5)c3)cc(C(F)(F)F)c2)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CNc2ncnc(Oc3cc(C(=O)Nc4cc(N5CCN(C)CC5)cc(C(F)(F)F)c4)ccc3Cl)c2O1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4ccnc5c4OCCN5)cc3)cc2S(C)(=O)=O)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2cc(NC(=O)Nc3ccc(Oc4ccnc5c4OCCN5)cc3)cc(S(C)(=O)=O)c2)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)Nc2cc(N3CCN(C)CC3)cc(S(C)(=O)=O)c2)cc1Oc1ncnc2c1OCC(C)(C)N2,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)Nc2ccc(C#CCCO)c(C(F)(F)F)c2)cc1Oc1ncnc2c1OCC(C)(C)N2,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)Nc2cc(N3CCN(C)CC3)cc(C(F)(F)F)c2)cc1Oc1ccnc2c1OCCCN2,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)Nc2ccc(C#CC(C)O)c(C(F)(F)F)c2)cc1Oc1ncnc2c1OCC(C)(C)N2,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc2S(C)(=O)=O)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)COc2c(ncnc2Oc2cc(C(=O)Nc3cc(C(C)(C)C)on3)ccc2Cl)N1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
NS(=O)(=O)c1cccc(NC(=O)Nc2ccc(Oc3ccnc4c3OCCN4)cc2)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(O)C#Cc1cc(NC(=O)c2ccc(Cl)c(Oc3ncnc4c3OCCN4)c2)cc(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCS(=O)(=O)c1cccc(NC(=O)Nc2ccc(Oc3ccnc4c3OCCN4)cc2)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1cccc(NC(=O)Nc2ccc(Oc3ccnc4c3OCCN4)cc2)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)Nc2cccc(C(F)F)c2)cc1Oc1ncnc2c1OCCN2,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)Nc2cc(C#CC(C)(C)O)cc(C(F)(F)F)c2)cc1Oc1ncnc2c1OCCN2,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)Nc2cccc(S(C)(=O)=O)c2)cc1Oc1ncnc2c1OCCN2,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)COc2c(ncnc2Oc2cc(C(=O)Nc3cc(C(C)(C)C)nn3-c3cccc(C#N)c3)ccc2Cl)N1,HPK1,medium,100.01,ic50,AU2018272986A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4nc(Cl)nc5c4OCCN5)c3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)Nc2cc(C#CCO)cc(C(F)(F)F)c2)cc1Oc1ncnc2c1OCCN2,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1COc2c(ncnc2Oc2cc(C(=O)Nc3cc(C(F)(F)F)ccc3N3CCN(C)CC3)ccc2Cl)N1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1COc2c(ncnc2Oc2cc(C(=O)Nc3cccc(N4CCN(C)CC4)c3)ccc2Cl)N1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)Nc2cc(C(C)(C)C)nn2-c2ccc(C#N)cc2)cc1Oc1ccnc2c1OCCN2,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)Nc2cc(C(C)(C)C)nn2-c2cccc(C#N)c2)cc1Oc1ccnc2c1OCCN2,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OC[C@@H](CN(C)C)N5)c3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)Nc2cc(/C=C/C#N)cc(C(F)(F)F)c2)cc1Oc1ncnc2c1OCCN2,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)Nc2cc(C#CC(N)=O)cc(C(F)(F)F)c2)cc1Oc1ncnc2c1OCCN2,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)Nc2cc(/C=C/C(N)=O)cc(C(F)(F)F)c2)cc1Oc1ncnc2c1OCCN2,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4ccnc5c4OCCN5)cc3)cc2)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)C1CN(c2cc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc(C(F)(F)F)c2)C1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2cc(NC(=O)c3cccc(Oc4ncnc5c4OCCN5)c3)cc(C(F)(F)F)c2)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)N1CC(C(=O)Nc2cc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc(C(F)(F)F)c2)C1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CC(=O)Nc1cc(NC(=O)c2ccc(Cl)c(Oc3ncnc4c3OCCN4)c2)cc(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2cc(NC(=O)Nc3ccc(Oc4ccnc5c4OCCN5)cc3)cc(C(F)(F)F)c2)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2cc(NC(=O)Nc3ccc(Oc4ncnc5c4OCCN5)cc3F)cc(C(F)(F)F)c2)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
N#Cc1cc(NC(=O)Nc2ccc(Oc3ncnc4c3OCCN4)cc2)cc(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Nc1cccc(C(F)(F)F)c1)c1ccc(Cl)c(Oc2ncnc3c2OC[C@@H](CN2CCOCC2)N3)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C#N)c1ccc(NC(=O)c2ccc(Cl)c(Oc3ncnc4c3OCCN4)c2)cc1C(F)(F)F,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
N#Cc1ccc(NC(=O)Nc2ccc(Oc3ncnc4c3OCCN4)cc2)cc1C(F)(F)F,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Nc1cccc(C(F)(F)F)c1)Nc1ccc(Oc2ncnc3c2OCCN3)c(Cl)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2cc(NC(=O)c3ccc(Cl)c(Oc4ccnc5c4OCCN5)c3)cc(C(F)(F)F)c2)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Nc1cc(N2CCN(C3COC3)CC2)cc(C(F)(F)F)c1)c1ccc(Cl)c(Oc2ccnc3c2OCCN3)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(Oc4ncnc5c4OCCN5)c3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCC(=O)Nc1cc(NC(=O)c2ccc(Cl)c(Oc3ncnc4c3OCCN4)c2)cc(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)[C@H]1COc2c(ncnc2Oc2cc(C(=O)Nc3cc(N4CCN(C)CC4)cc(C(F)(F)F)c3)ccc2Cl)N1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)[C@@H]1COc2c(ncnc2Oc2cc(C(=O)Nc3cc(N4CCN(C)CC4)cc(C(F)(F)F)c3)ccc2Cl)N1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Nc1cc(-c2cn[nH]c2)cc(C(F)(F)F)c1)c1ccc(Cl)c(Oc2ncnc3c2OCCN3)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2cc(NC(=O)Nc3ccc(Oc4ncnc5c4OCCN5)c(Cl)c3)cc(C(F)(F)F)c2)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(NC(=O)Nc2cc(N3CCN(C)CC3)cc(C(F)(F)F)c2)ccc1Oc1ncnc2c1OCCN2,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(Oc4ncnc5c4OCCN5)c(Cl)c3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2cc(NC(=O)c3ccc(Oc4ncnc5c4OCCN5)c(Cl)c3)cc(C(F)(F)F)c2)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1Oc2c(ncnc2Oc2cc(C(=O)Nc3cc(N4CCN(C)CC4)cc(C(F)(F)F)c3)ccc2Cl)NC1=O,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1COc2c(ncnc2Oc2cc(C(=O)Nc3cc(N4CCN(C)CC4)cc(C(F)(F)F)c3)ccc2C)N1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1COc2c(ncnc2Oc2cc(C(=O)Nc3cc(N4CCN(C)CC4)cc(C(F)(F)F)c3)ccc2C)N1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1COc2c(ncnc2Oc2cc(C(=O)Nc3cc(N4CCN(C)CC4)cc(C(F)(F)F)c3)ccc2Cl)N1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)[C@H]1CCN(Cc2cc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc(C(F)(F)F)c2)C1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)[C@@H]1CCN(Cc2cc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc(C(F)(F)F)c2)C1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2cc(NC(=O)Nc3ccc(Oc4ncnc5c4OCCN5)cc3)cc(C(F)(F)F)c2)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1cc(-c2cc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc(C(F)(F)F)c2)cn1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)Nc2cc(N3CCN(C)CC3)cc(C(F)(F)F)c2)cc1Oc1ncnc2c1OCC(C)(C)N2,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)Nc2cc(N3CCN(C)CC3)cc(C(F)(F)F)c2)cc1Oc1ncnc2c1OC[C@@H](C)N2,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CC(Oc2cc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc(C(F)(F)F)c2)C1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1CN(C)CCN1c1cc(NC(=O)c2ccc(Cl)c(Oc3ncnc4c3OCCN4)c2)cc(C(F)(F)F)c1,HPK1,medium,500,ic50,AU2018272986A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CN(C)CCN1c1cc(NC(=O)c2ccc(Cl)c(Oc3ncnc4c3OCCN4)c2)cc(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)Nc2cc(N3CC[C@H](N(C)C)C3)cc(C(F)(F)F)c2)cc1Oc1ccnc2c1OCCN2,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)Nc2cc(N3CCOCC3)cc(C(F)(F)F)c2)cc1Oc1ccnc2c1OCCN2,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CN(c2cc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc(C(F)(F)F)c2)CCN1C,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1CN(c2cc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc(C(F)(F)F)c2)CCN1C,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1C[C@@H]2C[C@H]1CN2c1cc(NC(=O)c2ccc(Cl)c(Oc3ncnc4c3OCCN4)c2)cc(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Nc1cc(N2CCOCC2=O)cc(C(F)(F)F)c1)c1ccc(Cl)c(Oc2ncnc3c2OCCN3)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1CNCCN1c1cc(NC(=O)c2ccc(Cl)c(Oc3ncnc4c3OCCN4)c2)cc(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CNCCN1c1cc(NC(=O)c2ccc(Cl)c(Oc3ncnc4c3OCCN4)c2)cc(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CN(c2cc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc(C(F)(F)F)c2)C[C@@H](C)O1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3cc(Cl)cc(Oc4ncnc5c4OCCN5)c3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3cc(Oc4ncnc5c4OCCN5)ccc3F)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(C(F)(F)F)c(Oc4ncnc5c4OCCN5)c3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(OC)c(Oc4ncnc5c4OCCN5)c3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(Oc4ncnc5c4CCCN5)c3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4C(O)CCN5)c3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4C(=O)CCN5)c3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)Nc2cc(N3CCN(C)CC3)cc(C(F)(F)F)c2)cc1Oc1ccnc2c1OCCN2,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(c2cc(NC(=O)c3ccc(C)c(Oc4ccnc5c4OCCN5)c3)cc(C(F)(F)F)c2)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2cc(NC(=O)c3ccc(C)c(Oc4ccnc5c4OCCN5)c3)cc(C(F)(F)F)c2)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(Sc4ncnc5c4OCCN5)c3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(Oc4ncnc5c4OCC(=O)N5)c3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)Nc2cc(N3CC[C@@H](N(C)C)C3)cc(C(F)(F)F)c2)cc1Oc1ncnc2c1OCCN2,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)Nc2cc(N3CCOCC3)cc(C(F)(F)F)c2)cc1Oc1ncnc2c1OCCN2,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)Nc2cc(N3CCN(CC4CC4)CC3)cc(C(F)(F)F)c2)cc1Oc1ncnc2c1OCCN2,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCN1CCN(c2cc(NC(=O)c3ccc(C)c(Oc4ncnc5c4OCCN5)c3)cc(C(F)(F)F)c2)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)Nc2cc(N3CCN(C(C)C)CC3)cc(C(F)(F)F)c2)cc1Oc1ncnc2c1OCCN2,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)Nc2ccc(CN3CCN(C(C)C)CC3)c(C(F)(F)F)c2)cc1Oc1ncnc2c1OCCN2,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(c2cc(NC(=O)c3ccc(C)c(Oc4ncnc5c4OCCN5)c3)cc(C(F)(F)F)c2)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)cc1Oc1ncnc2c1OCCN2,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4O[C@@H](C)CN5)c3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCC(=O)N5)c3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2cc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCC(=O)N5)c3)cc(C(F)(F)F)c2)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCCN(c2cc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc(C(F)(F)F)c2)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Nc1cc(N2CCC(F)CC2)cc(C(F)(F)F)c1)c1ccc(Cl)c(Oc2ncnc3c2OCCN3)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
C#CCN1CCN(c2cc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc(C(F)(F)F)c2)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)NCc1cc(NC(=O)c2ccc(Cl)c(Oc3ncnc4c3OCCN4)c2)cc(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Nc1cc(N2CC[C@H](O)C2)cc(C(F)(F)F)c1)c1ccc(Cl)c(Oc2ncnc3c2OCCN3)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Nc1cc(N2CCN(C3COC3)CC2)cc(C(F)(F)F)c1)c1ccc(Cl)c(Oc2ncnc3c2OCCN3)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
C=CC(=O)Nc1cc(NC(=O)c2ccc(Cl)c(Oc3ncnc4c3OCCN4)c2)cc(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Nc1cc(N2CCN(C3CC3)CC2)cc(C(F)(F)F)c1)c1ccc(Cl)c(Oc2ncnc3c2OCCN3)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
N#CCC(=O)N1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Nc1cc(N2CC[C@@H](O)C2)cc(C(F)(F)F)c1)c1ccc(Cl)c(Oc2ncnc3c2OCCN3)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Nc1cc(N2CCC(F)(F)CC2)cc(C(F)(F)F)c1)c1ccc(Cl)c(Oc2ncnc3c2OCCN3)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)[C@H]1CCN(c2cc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc(C(F)(F)F)c2)C1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)[C@@H]1CCN(c2cc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc(C(F)(F)F)c2)C1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Nc1cc(N2CCOCC2)cc(C(F)(F)F)c1)c1ccc(Cl)c(Oc2ncnc3c2OCCN3)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Nc1cc(F)cc(C(F)(F)F)c1)c1ccc(Cl)c(Oc2ncnc3c2OCCN3)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
N#Cc1cc(NC(=O)c2ccc(Cl)c(Oc3ncnc4c3OCCN4)c2)cc(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ncc(NC(=O)c2ccc(Cl)c(Oc3ncnc4c3OCCN4)c2)cc1C(F)(F)F,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN[C@H]1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc2C(F)(F)F)C1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN[C@@H]1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc2C(F)(F)F)C1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)[C@@H]1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc2C(F)(F)F)C1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)[C@H]1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc2C(F)(F)F)C1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)C1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc2C(F)(F)F)C1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)Cc1cc(NC(=O)c2ccc(Cl)c(Oc3ncnc4c3OCCN4)c2)cc(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Nc1cc(N2CCS(=O)(=O)CC2)cc(C(F)(F)F)c1)c1ccc(Cl)c(Oc2ncnc3c2OCCN3)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2cc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc(C(F)(F)F)c2)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Nc1cc(C2CCNCC2)cc(C(F)(F)F)c1)c1ccc(Cl)c(Oc2ncnc3c2OCCN3)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Nc1cc(N2CCNCC2)cc(C(F)(F)F)c1)c1ccc(Cl)c(Oc2ncnc3c2OCCN3)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
N#CC1(c2cccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)c2)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C#N)c1cccc(NC(=O)c2ccc(Cl)c(Oc3ncnc4c3OCCN4)c2)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCN(C)c1cc(NC(=O)c2ccc(Cl)c(Oc3ncnc4c3OCCN4)c2)cc(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)C1CCN(c2cc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc(C(F)(F)F)c2)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2cc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc(C(F)(F)F)c2)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Nc1cc(N2CCN(CC3CC3)CC2)cc(C(F)(F)F)c1)c1ccc(Cl)c(Oc2ncnc3c2OCCN3)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCN1CCN(c2cc(NC(=O)c3ccc(Cl)c(Cc4ncnc5c4OCCN5)c3)cc(C(F)(F)F)c2)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)N1CCN(c2cc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc(C(F)(F)F)c2)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(c2cc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc(C(F)(F)F)c2)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCC(Oc2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Nc1cccc(C(F)(F)F)c1)c1ccc(Cl)c(Oc2ncnc3c2OCCN3)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCNC(=O)c1ccc(NC(=O)c2ccc(Cl)c(Oc3ncnc4c3OCCN4)c2)cc1C(F)(F)F,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc2Br)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(C(=O)c2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc2C)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc2Cl)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Nc1ccc(N2CCOCC2)c(C(F)(F)F)c1)c1ccc(Cl)c(Oc2ncnc3c2OCCN3)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Nc1ccc(CN2CCNCC2)c(C(F)(F)F)c1)c1ccc(Cl)c(Oc2ncnc3c2OCCN3)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Oc4ncnc5c4OCCN5)c3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(F)c(Oc4ncnc5c4OCCN5)c3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3cccc(Oc4ncnc5c4OCCN5)c3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4c(C#N)cnc5c4OCCN5)cc3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Nc1ccc(F)cc1)C1(C(=O)Nc2ccc(Oc3ncnc4c3OCCN4)c(F)c2)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Nc1ccc(Oc2ncnc3c2OCCN3)cc1)Nc1cccc(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1Oc2c(ncnc2Oc2cc(C(=O)Nc3cc(N4CCN(C)CC4)cc(C(F)(F)F)c3)ccc2Cl)NC1=O,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(NC(=O)c2ccc(Cl)c(Oc3ncnc4c3OCCN4)c2)cc(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Nc1cc(O)cc(C(F)(F)F)c1)c1ccc(Cl)c(Oc2ncnc3c2OCCN3)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(Nc4ncnc5c4OCCN5)c3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCN(C)Cc1ccc(NC(=O)c2ccc(Cl)c(Oc3ncnc4c3OCCN4)c2)cc1C(F)(F)F,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1cc2c(cn1)cnn2-c1cccc(N)n1,HPK1,medium,518,ic50,Merck-Identification of Potent Reverse Indazole Inhibitors for HPK1, not Ki or Kd; not used in NCI fingerprint analysis
CCOc1cccc(F)c1-c1cc2c(cn1)cnn2-c1ccc(N2CCN(C)CC2)cc1,HPK1,medium,557,ic50,Merck-Identification of Potent Reverse Indazole Inhibitors for HPK1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-n3ncc4cnc(-c5ccccc5)cc43)cc2)CC1,HPK1,medium,826,ic50,Merck-Identification of Potent Reverse Indazole Inhibitors for HPK1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]ccc56)cnc4C[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C#N)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5CC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(CO)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C#N)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2cnc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]ccc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1c2cc(Oc3ccnc4[nH]c(CO)cc34)ccc2CCN1C(=O)Nc1cnc(OC2CCN(CCO)CC2)c(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]ccc56)cnc4[C@@H](C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3ccc4c(c3)[C@H](C)N(C(=O)Nc3cnc5c(N6CCN(C)CC6)cccc5c3)CC4)ccnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Nc5ccnc6[nH]ccc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]ccc56)cnc4C(C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]c(C)cc56)cnc4C(C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc6[nH]c(C7CC7)cc56)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc(C(=O)NC)c5)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc6[nH]c(C#N)cc56)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ncnn6cc(C#N)cc56)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnn6cc(-c7cnn(C)c7)cc56)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]c(C)cc56)ccc4C(C(C)C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]c(C)cc56)c(F)cc4C(C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4c(C)cc(Oc5ccnc6[nH]ccc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc6[nH]c(C)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnn6cc(Br)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5cc(NC6=NC=CC6)ncn5)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5cc(Nc6ncc[nH]6)ncn5)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc(NC(C)=O)c5)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc(NC)c5)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc6[nH]c(=O)ccc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5cc(NC(=O)C6CC6)ncn5)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5cc(NC(C)=O)ncn5)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ncnn6cc(F)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ncnc6[nH]cnc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ncnc6[nH]ncc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ncnc6[nH]ccc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ncnn6cc(-c7cnn(C)c7)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]ccc56)cnc4C[C@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1Cc2ncc(Oc3ccnc4[nH]ccc34)cc2CN1C(=O)Nc1ccc(CN2CCN(CC)CC2)c(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]ccc56)ccc4C(C(F)(F)F)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]ccc56)ccc4C(C(F)(F)F)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]c(C7(O)CC7)cc56)ccc4C(C(F)(F)F)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc6[nH]c(C7(O)CC7)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Nc1ccc(CN2CCNCC2)c(C(F)(F)F)c1)N1CCc2ccc(Oc3ccnc4[nH]c(C5(O)CC5)cc34)cc2C1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc6[nH]c(C(=O)N(C)C)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)C(=O)c1cc2c(Oc3ccc4c(c3)CN(C(=O)Nc3ccc(CN5CCNCC5)c(C(F)(F)F)c3)CC4)ccnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5c(F)cnc6[nH]c(C7(O)CC7)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Nc1ccc(CN2CCNCC2)c(C(F)(F)F)c1)N1CCc2ccc(Oc3c(F)cnc4[nH]c(C5(O)CC5)cc34)cc2C1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5c(F)cnc6[nH]c(C(=O)N(C)C)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)C(=O)c1cc2c(Oc3ccc4c(c3)CN(C(=O)Nc3ccc(CN5CCNCC5)c(C(F)(F)F)c3)CC4)c(F)cnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]c(C)cc56)c(C)nc4C(C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]c(C)cc56)ccc4C(C#N)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)C3CCc4ncc(Oc5ccnc6[nH]ccc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)C3Cc4cc(Oc5ccnc6[nH]ccc56)cnc4C(C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(Cc2ncc(NC(=O)N3CCc4cc(F)c(Nc5c(F)cnc6[nH]c(-c7cnn(C)c7)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(Cc2ccc(NC(=O)N3CCc4cc(F)c(Nc5c(F)cnc6[nH]c(-c7cnn(C)c7)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(Cc2ncc(NC(=O)N3CCc4ccc(Nc5c(F)cnc6[nH]c(-c7cnn(C)c7)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCC1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Nc3c(F)cnc4[nH]c(-c5cnn(C)c5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Nc5c(F)cnc6[nH]c(-c7cnn(C)c7)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1Cc2ccc(Oc3ccnc4[nH]c(C(=O)N(C)C)cc34)cc2CN1C(=O)Nc1cnc(CN2CCN(C)CC2)c(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1Cc2ccc(Oc3c(F)cnc4[nH]c(C5(O)CC5)cc34)cc2CN1C(=O)Nc1ccc(CN2CCN(C)CC2)c(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1Cc2ccc(Oc3c(F)cnc4[nH]c(C5(O)CC5)cc34)cc2CN1C(=O)Nc1cnc(CN2CCN(C)CC2)c(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1Cc2ccc(Oc3ccnc4[nH]c(C(=O)N(C)C)cc34)cc2CN1C(=O)Nc1cnc(OC2CCN(C)CC2)c(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1Cc2ccc(Oc3ccnc4[nH]c(C(=O)N(C)C)cc34)cc2CN1C(=O)Nc1cnc(O[C@@H]2CCN(C)C[C@@H]2O)c(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1Cc2ccc(Oc3c(F)cnc4[nH]c(-c5cnn(C)c5)cc34)cc2CN1C(=O)Nc1cnc(CN2CCN(C)CC2)c(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1Cc2ccc(Oc3c(F)cnc4[nH]c(-c5cnn(C)c5)cc34)cc2CN1C(=O)Nc1ccc(CN2CCN(C)CC2)c(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1Cc2ccc(Oc3ccnc4[nH]c(C5(O)CC5)cc34)cc2CN1C(=O)Nc1cnc(CN2CCN(C)CC2)c(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1Cc2ccc(Oc3ccnc4[nH]c(C(=O)N(C)C)cc34)cc2CN1C(=O)Nc1ccc(CN2CCN(C)CC2)c(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(CCO)CC3)c(C(F)F)c2)Cc2cc(Oc3ncnc4[nH]c(C5CC5)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(CCO)CC3)c(C(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C(N)=O)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCC1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5CCN(C(=O)C6CC6)CC5)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3c(F)cnc4[nH]c(C(=O)N(C)C)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3c(F)cnc4[nH]c(CO)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(CCO)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C#N)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CN(C(=O)Nc2ccc(CN3CCN(CCO)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C#N)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C#N)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5(O)COC5)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5(O)COC5)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C(N)=O)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C(N)=O)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C#N)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C#N)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(CCO)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5CC5)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(CCO)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5CC5)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(CCO)CC3)c(C(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5CC5)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(CCO)CC3)c(C(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5CC5)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(CCO)CC3)c(C(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(CO)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(CCO)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(CO)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(CCO)CC3)c(C(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C#N)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(CCO)CC3)c(C(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C#N)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C#N)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C#N)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCNCC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C#N)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCNCC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C#N)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5(O)COC5)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5(O)COC5)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5(O)COC5)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5(O)COC5)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCNCC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5(O)COC5)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCNCC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5(O)COC5)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(CO)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(CO)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(CCO)CC3)c(C(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(CO)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(CCO)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(CO)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCNCC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(CO)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCNCC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(CO)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)F)c2)Cc2cc(Oc3ncnc4[nH]c(C5CC5)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(CCO)CC3)c(C(F)F)c2)Cc2cc(Oc3ncnc4[nH]c(C5CC5)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)F)c2)Cc2cc(Oc3ncnc4[nH]c(C5CC5)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCC1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5=CCN(C(=O)C6CC6)CC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C(C)=O)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C(C)C)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C=C(C)c1cc2c(Oc3cnc4c(c3)CN(C(=O)Nc3ccc(CN5CCN(C)CC5)c(C(F)(F)F)c3)C[C@@H]4CC)ccnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5=CCOC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(CS(C)(=O)=O)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(-c5cn[nH]c5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(-c5cc[nH]n5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCNCC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(-c5n[nH]c(C)n5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCNCC3)c(C(F)(F)F)c2)Cc2cc(Oc3ncnn4cc(C(=O)N(C)C)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCNCC3)c(C(F)(F)F)c2)Cc2cc(Oc3c(F)cnc4[nH]c(C(=O)N(C)C)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ncnn4cc(C(=O)N(C)C)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3c(F)cnc4[nH]c(C(=O)N(C)C)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(-c5n[nH]c(C)n5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(CCF)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C(=O)N(C)C)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2cc(C(F)(F)F)c(CN3CCN(C)CC3)cc2F)Cc2cc(Oc3ccnc4[nH]c(C(=O)N(C)C)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCNCC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(-c5noc(C)n5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCNCC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(-c5noc(=O)[nH]5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ncnc4[nH]c(C(=O)N(C)C)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(-c5noc(C)n5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(-c5noc(=O)[nH]5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C(=O)N(C)C)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCNCC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(-c5n[nH]c(=O)o5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCNCC3)c(C(F)(F)F)c2)Cc2cc(Oc3ncnc4[nH]c(C(=O)NC)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCNCC3)c(C(F)(F)F)c2)Cc2cc(Oc3ncnc4[nH]c(C(=O)N(C)C)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCNCC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnn4cc(C(=O)NC)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCNCC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnn4cc(C(=O)N(C)C)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCNCC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C#N)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCNCC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C(=O)N(C)C)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ncnc4[nH]c(C(=O)NC)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnn4cc(C(=O)NC)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnn4cc(C(=O)N(C)C)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(-c5n[nH]c(=O)o5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCNCC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(-c5nnc(C)o5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(-c5nnc(C)o5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C(=O)N(C)CCCO)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C(=O)N5CC[C@@H](O)C5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C(=O)N5CC[C@H](O)C5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C(=O)NCCCO)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C(=O)NCCO)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C(=O)N(C)CCO)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C(=O)N5CC(F)C5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C(=O)N5CC(C#N)C5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C(=O)N5CCCC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5(O)CC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5(O)CC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3c(F)cnc4[nH]c(CO)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5c(F)cnc6[nH]c(CO)cc56)cnc4[C@@H](C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3cnc4c(c3)CN(C(=O)Nc3ccc(CN5CCNC6(CC6)C5)c(C(F)(F)F)c3)C[C@H]4C)ccnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3cnc4c(c3)CN(C(=O)Nc3ccc(CN5CCN(C)CC5)c(OC(F)F)c3)C[C@H]4C)ccnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCC1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3cc(NC(=O)c4cnn(C)c4)ncc3F)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3cnc4c(c3)CN(C(=O)Nc3ccc(CN5CCN(C)CC5)c(C(F)(F)F)c3)C[C@H]4C)ccnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3cnc4c(c3)CN(C(=O)Nc3ccc(CN5CCN(C)CC5)c(C(F)(F)F)c3)C[C@@H]4C)ccnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3cnc4c(c3)CN(C(=O)Nc3ccc(CN5CCN(C)CC5)c(OC(F)(F)F)c3)C[C@H]4C)ccnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3c(F)cnc4[nH]c(C5(O)COC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCC1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3cc(NC(=O)OC)ncc3F)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C(N)=O)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C(=O)NC)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C(N)=O)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C(=O)O)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5CC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2cnc(OC3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5(O)CC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5(O)CC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(CO)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2cnc(OC3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5(O)CC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5(O)CC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]c(CO)cc56)cnc4[C@@H](C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5CC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5CC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCC1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5CCOCC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2cnc(O[C@@H]3CCN[C@H](C)C3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5CC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(CCO)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5CC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCNCC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5CC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCC1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5CCOC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCC1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5=CCOC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCC1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5=CCOCC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(CCO)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5CC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5CC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCNCC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5CC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(CO)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(CO)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCNCC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(CO)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCC1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(-c5cnn(C)c5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5(O)COC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5(O)COC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5(O)COC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5(O)COC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCNCC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5(O)COC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCNCC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5(O)COC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(CO)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(CO)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCNCC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(CO)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C#N)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1CN(C(=O)Nc2cnc(OC3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5CC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2cnc(OC3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C#N)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCC1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C(C)O)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3c(F)cnc4[nH]c(-c5cnn(C)c5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ncnc4[nH]c(C5CC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ncnc4[nH]c(C5CC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2cnc(OC3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5CC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2cnc(OC3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(CCOC)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2cnc(OC3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(CCOC)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2cnc(OC3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C#N)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1Cc2ncc(Oc3ccnc4[nH]ccc34)cc2CN1C(=O)Nc1ccc(CN2CCN(CC)CC2)c(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5CC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]c(-c7cnn(C)c7)nc56)cnc4C(C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(CO)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2cnc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(CCOC)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2cnc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C#N)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2cnc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5CC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C5CC5)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(CCOC)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(CCOC)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C#N)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]c(C7CC7)nc56)cnc4C(C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]c(CO)cc56)cnc4[C@H](C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]c(=O)[nH]c56)cnc4C(C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc(NC)c5)cnc4C(C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2cnc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]ccc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]ccc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]ccc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]c(=O)ccc56)cnc4C(C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6c5CCC(=O)N6)cnc4C(C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C(=O)N(C)C)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C#N)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5cc(NC(=O)c6cnn(C)c6)ncc5F)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5c(F)cnc6[nH]c(C7(O)COC7)cc56)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5cc(NC(=O)C6CC6)ncc5F)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5cc(NC(=O)c6ccnnc6)ncc5F)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5cc(NC(=O)OC)ncc5F)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1c2cc(Oc3ccnc4[nH]c(CO)cc34)ccc2CCN1C(=O)Nc1ccc(CN2CCN(CCO)CC2)c(C(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1c2cc(Oc3ccnc4[nH]c(C5(O)COC5)cc34)ccc2CCN1C(=O)Nc1ccc(CN2CCN(CCO)CC2)c(C(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1c2cc(Oc3ccnc4[nH]c(C5(O)COC5)cc34)ccc2CCN1C(=O)Nc1ccc(CN2CCN(C)CC2)c(C(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1c2cc(Oc3ccnc4[nH]c(CO)cc34)ccc2CCN1C(=O)Nc1ccc(CN2CCN(C)CC2)c(C(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1c2cc(Oc3ccnc4[nH]c(CO)cc34)ccc2CCN1C(=O)Nc1ccc(CN2CCNCC2)c(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1c2cc(Oc3ccnc4[nH]c(C5(O)COC5)cc34)ccc2CCN1C(=O)Nc1ccc(CN2CCNCC2)c(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1c2cc(Oc3ccnc4[nH]c(C5(O)COC5)cc34)ccc2CCN1C(=O)Nc1cnc(OC2CCN(C)CC2)c(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1c2cc(Oc3ccnc4[nH]c(CO)cc34)ccc2CCN1C(=O)Nc1cnc(OC2CCN(C)CC2)c(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc6[nH]c(CO)cc56)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C)CCC1Oc1ncc(NC(=O)N2CCc3ccc(Oc4ccnc5[nH]c(C)cc45)cc3[C@@H]2C)cc1C(F)(F)F,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(Cc2cc(F)c(NC(=O)N3CCc4ccc(Oc5c(F)cnc6[nH]c(-c7cnn(C)c7)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5c(F)cnc6[nH]c(-c7cnn(C)c7)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cn1cc(-c2cc3c(Oc4ccc5c(c4)CN(C(=O)Nc4ccc(CN6CCN(CCO)CC6)c(C(F)(F)F)c4)CC5)c(F)cnc3[nH]2)cn1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(Oc2ncc(NC(=O)N3CCc4ccc(Oc5c(F)cnc6[nH]c(-c7cnn(C)c7)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3c(F)cnc4[nH]c(-c5cnn(C)c5)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CN(C(=O)Nc2cnc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3c(F)cnc4[nH]c(-c5cnn(C)c5)cc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(Cc2ncc(NC(=O)N3CCc4ccc(Oc5c(F)cnc6[nH]c(-c7ccncc7)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5c(F)cnc6[nH]c(-c7cn[nH]c7)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(Cc2ncc(NC(=O)N3CCc4ccc(Oc5c(F)cnc6[nH]c(-c7cn[nH]c7)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5c(F)cnc6[nH]c(-c7cccnc7)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(Cc2ncc(NC(=O)N3CCc4ccc(Oc5c(F)cnc6[nH]c(-c7cccnc7)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5c(F)cnc6[nH]c(-c7ccncc7)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(Oc2ncc(NC(=O)N3CCc4ccc(Oc5c(F)cnc6[nH]c(-c7cnn(C)c7)cc56)cc4C3)cc2C(F)(F)F)[C@@H](O)C1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1c2cc(Oc3c(F)cnc4[nH]c(-c5cnn(C)c5)cc34)ccc2CCN1C(=O)Nc1ccc(CN2CCN(C)CC2)c(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5c(F)cnc6[nH]c(-c7cnn(C)c7)cc56)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(Cc2ncc(NC(=O)N3CCc4ccc(Oc5c(F)cnc6[nH]c(-c7cnn(C)c7)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5c(F)cnc6[nH]c(-c7cnn(C)c7)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]ccc56)cnc4[C@H](C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ncnc6[nH]c(C)cc56)cnc4[C@@H](C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ncnc6[nH]c(C)cc56)cnc4[C@H](C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ncc(Oc5ccnc6[nH]ccc56)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3ccc4c(c3)[C@H](C)N(C(=O)Nc3ccc5c(N6CCN(C)CC6)cccc5c3)CC4)ccnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4nc(C)c(Oc5ccnc6[nH]ccc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4cc(Oc5ccnc6[nH]ccc56)ccc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]c(C)cc56)ccc4C(O)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CC(=O)c4ccc(Oc5ccnc6[nH]c(C)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)C3CCc4ccc(Oc5ccnc6[nH]c(C)cc56)cc4N3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)C3CCc4ccc(Oc5ccnc6[nH]c(C)cc56)cc4N3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)C3CCc4ccc(Oc5ncnn6cccc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ncc(Oc5ccnc6[nH]ccc56)cc4C3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCC1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Nc5ccnc6[nH]c(C)cc56)cnc4C(C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3cnc4c(c3)CN(C(=O)Nc3cnc(OC5CCN(C)CC5O)c(C(F)(F)F)c3)CC4C)ccnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ncnc6[nH]c(C)cc56)cnc4C(C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]ncc56)cnc4C(C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3cnc4c(c3)CN(C(=O)Nc3cnc(OC5CCN(C)CC5)c(C(F)(F)F)c3)CC4C)ncnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC1CN(C(=O)Nc2cnc(OC3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]ncc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3cnc4c(c3)CN(C(=O)Nc3cnc(OC5CCN(C)CC5)c(C(F)(F)F)c3)CC4C)ccnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ncc(Oc5ccnc6[nH]ccc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ncc(Oc5ncnn6cccc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3ccc4c(c3)[C@H](C)N(C(=O)Nc3cnc(OC5CCN(CCO)CC5)c(C(F)(F)F)c3)CC4)ccnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3ccc4c(c3)[C@H](C)N(C(=O)Nc3cnc(NC5CCN(C)CC5)c(C(F)(F)F)c3)CC4)ccnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCC(Oc2ncc(NC(=O)N3CCc4ccc(Oc5ccnc6[nH]c(C)cc56)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3ccc4c(c3)[C@H](C)N(C(=O)Nc3cnc(OC5CCN(C)CC5)c(C(F)(F)F)c3)CC4)ccnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3ccc4c(c3)[C@H](C)N(C(=O)Nc3cnc(OC5CCNCC5)c(C(F)(F)F)c3)CC4)ccnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1c2cc(Oc3ccnc4[nH]ccc34)ccc2CCN1C(=O)Nc1cnc(OC2CCN(C)CC2)c(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ncc(NC(=O)N3CCc4ccc(Oc5ccnc6[nH]c(C)cc56)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ncnc6[nH]c(C)cc56)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc6[nH]c(-c7cnn(C)c7)cc56)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc6[nH]c(CCOC)cc56)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc6[nH]c(CCO)cc56)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc6[nH]c(C7(O)COC7)cc56)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCc1cc2c(Oc3ccc4c(c3)[C@H](C)N(C(=O)Nc3ccc(CN5CCN(CC)CC5)c(C(F)(F)F)c3)CC4)cccc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1c2cc(Oc3ccnc4[nH]ccc34)ccc2CCN1C(=O)Nc1ccc(CN2CCN(CCO)CC2)c(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1c2cc(Oc3ccnc4[nH]ccc34)ccc2CCN1C(=O)Nc1ccc(CN2CCN(CCO)CC2)c(C(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1c2cc(Oc3ccnc4[nH]ccc34)ccc2CCN1C(=O)Nc1ccc(OC2CCN(CCO)CC2)c(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnn6cc(C#N)cc56)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnn6cncc56)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc6[nH]ncc56)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc6[nH]ccc56)cc4[C@@H]3C)cc2C(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc6[nH]ccc56)cc4[C@@H]3C)cc2Cl)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1c2cc(Oc3ccnc4[nH]ccc34)ccc2CCN1C(=O)Nc1ccc(CN2CCN(C)CC2)c(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1c2cc(Oc3ccnc4[nH]ccc34)ccc2CCN1C(=O)Nc1ccc(CN2CCNCC2)c(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc6[nH]ccc56)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]ccc56)ccc4CC3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3ccc4c(c3)CN(C(=O)Nc3cnc(OC5CCN(C)CC5O)c(C(F)(F)F)c3)CC4C)ccnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3ccc4c(c3)CN(C(=O)Nc3cnc(OC5CCN(C)CC5)c(C(F)(F)F)c3)CC4C)ccnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4cc(F)c(Oc5ccnc6[nH]c(C)cc56)cc4C3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]ccc56)ccc4C4(CC4)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCC1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]ccc34)ccc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]c(C)cc56)ccc4C(C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4c(F)cc(Oc5ccnc6[nH]ccc56)cc4C3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4cc(Br)c(Oc5ccnc6[nH]ccc56)cc4C3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1c2cc(Oc3ccnc4[nH]ccc34)ccc2CCN1C(=O)Nc1cc(C(F)(F)F)c(OC2CCN(C)CC2)cn1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]ccc56)ccc4C(C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]ccc56)c(F)cc4C(C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4cc(F)c(Oc5ccnc6[nH]ccc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc6[nH]c(C)cc56)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(Oc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc6[nH]ccc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5c(F)cnc6[nH]ccc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc6c5CCN6)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc6[nH]ccc56)c(F)c4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc6[nH]ccc56)c(C)c4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4cc(C)c(Oc5ccnc6[nH]ccc56)cc4C3)cc2C(C)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc6[nH]ccc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnn6cc(-c7cnn(C)c7)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnn6cc(-c7c[nH]cn7)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnn6cc(Cl)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnn6cc(F)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc6[nH]cnc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnn6cccc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc(NC(=O)C6CC6)c5)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc6c5CCC(=O)N6)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ncnn6cc(C)cc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc6[nH]ncc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5cc(NC)ncn5)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ncnn6cccc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N5CCC(O)CC5)c5sccc5[nH]c4=O)[nH]c3c2)CC1,HPK1,medium,500,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc3nc(-c4c(N5CCOCC5)c5sccc5[nH]c4=O)[nH]c3c2)CC1,HPK1,medium,500,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2[nH]c(=O)c(-c3nc4ccc(N5CCN(C)CC5)cc4[nH]3)c(N)c2s1,HPK1,medium,500,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
Cc1csc2[nH]c(=O)c(-c3nc4ccc(N5CCN(C)CC5)cc4[nH]3)c(NC3CCOCC3)c12,HPK1,medium,500,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
COc1csc2[nH]c(=O)c(-c3nc4ccc(N5CCN(C)CC5)cc4[nH]3)c(N)c12,HPK1,medium,500,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(N)c(-c3nc4ccc(N5CCN(C)CC5)cc4[nH]3)c(=O)[nH]c2s1,HPK1,medium,500,ic50,WO2016205942A1_Original_document_20201120110713, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1ccc2c(c1)C(=C(C)c1ccc(N3CCN(C4COC4)CC3)nc1)C(=O)N2,HPK1,medium,500,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1ccc2c(c1)C(=Cc1ccc(N3CCN(C4COC4)CC3)cc1)C(=O)N2,HPK1,medium,500,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c(C=C2C(=O)Nc3ccc(-c4ccccc4F)cc32)c(C)c1-c1ccc(N2CCN(C)CC2)cc1,HPK1,medium,500,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1ccc2c(c1)C(=Cc1ccccc1)C(=O)N2,HPK1,medium,500,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1-c1ccccc1,HPK1,medium,500,ic50,WO2020070332A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1CN(C)CCN1c1cc(NC(=O)c2ccc(Cl)c(Oc3ncnc4c3OCCN4)c2)cc(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2018215668A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc(C5CC(=O)NC5=O)cc4)cc23)cc1,HPK1,medium,910,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccnc(C(=O)N(C)C)c4)c3c2)ccc1N1CCN(C)CC1,HPK1,medium,752,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)ccc1-n1nccn1,HPK1,medium,523,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5nc(C(=O)N6CC(N(C)C)C6)co5)c4c3)cc2C#N)CC1,HPK1,medium,728,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccccc1-c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)cc23)cc1,HPK1,medium,539,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CC(c1ccc(C(=O)N(C)C)cc1)c1c[nH]c2ncc(-c3ccc(N4CCN(C)CC4)cc3)nc12,HPK1,medium,703,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccccc1-c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)nc23)cc1,HPK1,medium,864,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N5CC(O)C5)cc4)c3c2)cc2c1C(=O)N(C)CC2,HPK1,medium,827,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)C(=O)c1ccc(-c2c[nH]c3ncc(C4=CC5OCCNC(=O)C5C=C4)cc23)cc1,HPK1,medium,726,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc2c1C(=O)N(C)CC2,HPK1,medium,516,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)C(=O)c1ccc(-c2c[nH]c3ncc(-c4ccc5c(c4)OCCN(C)C5=O)cc23)cc1,HPK1,medium,594,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c[nH]c2ncc(-c3ccc(C(F)(F)F)c(P(C)(C)=O)c3)cc12,HPK1,not active,1000,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c[nH]c2ncc(-c3ccc(NC4COC4)c(P(C)(C)=O)c3)cc12,HPK1,not active,1000,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c[nH]c2ncc(-c3cc(NC(C)=O)cc(P(C)(C)=O)c3)cc12,HPK1,not active,1000,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c[nH]c2ncc(-c3ccc(CN(C)C)c(P(C)(C)=O)c3)cc12,HPK1,not active,1000,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
CCc1c[nH]c2ncc(-c3cc(C)cc(P(C)(C)=O)c3)cc12,HPK1,not active,1000,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc3ccn(-c4ccccc4P(C)(C)=O)c3n1)CN(C)CC2,HPK1,not active,1000,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cccc(F)c1-c1cc2c(-c3cnn(C4CCNCC4)c3)cnc(N)c2cc1C#N,HPK1,active,50,ic50,WO2021175271A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(-c2c[nH]c3ncc(C#N)c(Oc4ccc(NC5=NCC(F)(CO)CO5)cc4F)c23)c(F)c1,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Fc1cc(NC2=NCC3(COC3)CO2)cc(F)c1Oc1ncnc2[nH]cc(C3CC3)c12,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CC1(CO)CN=C(Nc2cc(F)c(Oc3ncnc4[nH]cc(C5CC5)c34)c(F)c2)OC1,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CN1CC(C(=O)c2ccc(-c3c[nH]c4ncnc(Oc5c(F)cc(NC6=NCC(C)(CO)CO6)cc5F)c34)cc2)C1,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)C1CN(C(=O)c2ccc(-c3c[nH]c4ncnc(Oc5c(F)cc(NC6=NCC(C)(CO)CO6)cc5F)c34)cc2)C1,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1c[nH]c2ncc(C#N)c(Oc3ccc(NC4=NCC(F)(CO)CO4)cc3F)c12,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CC1(CO)CN=C(Nc2cc(F)c(Oc3ncnc4[nH]cc(Cl)c34)c(F)c2)OC1,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CC1(CO)CN=C(Nc2cc(F)c(Oc3ncnc4[nH]cc(I)c34)c(F)c2)OC1,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(-c2c[nH]c3nccc(Oc4c(F)cc(NC5=NCC6(CC6)CO5)cc4F)c23)c(F)c1,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(-c2c[nH]c3ncnc(Oc4c(F)cc(NC5=NCC(F)(CO)CO5)cc4F)c23)c(F)c1,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(-c2c[nH]c3ncnc(Oc4c(F)cc(NC5=NCC(C)(CO)CO5)cc4F)c23)c(F)c1,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(-c2c[nH]c3ncc(C#N)c(Oc4ccc(NC5=NCC(C)(CO)CO5)cc4F)c23)c(F)c1,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
N#Cc1cnc2[nH]cc(-c3ccc(F)cc3)c2c1Oc1ccc(NC2=NCC(F)(CO)CO2)cc1F,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1c[nH]c2ncnc(Oc3c(F)cc(NC4=NCC(F)(CO)CO4)cc3F)c12,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Fc1ccc(-c2c[nH]c3ncnc(Oc4c(F)cc(NC5=NCC6(CC6)CO5)cc4F)c23)cc1,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CC1(CO)CN=C(Nc2cc(F)c(Oc3ncnc4[nH]cc(C5(C(F)(F)F)CC5)c34)c(F)c2)OC1,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1c[nH]c2ncnc(Oc3c(F)cc(NC4=NCC(C)(CO)CO4)cc3F)c12,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
O=C(c1ccc(-c2c[nH]c3ncnc(Oc4c(F)cc(NC5=NCC6(CC6)CO5)cc4F)c23)cc1)N1CC2(COC2)C1,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2c[nH]c3ncnc(Oc4c(F)cc(NC5=NCC(C)(CO)CO5)cc4F)c23)ccc1F,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)C(=O)c1ccc(-c2c[nH]c3ncnc(Oc4c(F)cc(NC5=NCC(C)(CO)CO5)cc4F)c23)cc1,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CC1(CO)CN=C(Nc2cc(F)c(Oc3ncnc4[nH]cc(-c5ccc(C#N)cc5F)c34)c(F)c2)OC1,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
COCCCN(C)C(=O)c1ccc(-c2c[nH]c3ncnc(Oc4c(F)cc(NC5=NCC(C)(CO)CO5)cc4F)c23)cc1,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CC1(CO)CN=C(Nc2cc(F)c(Oc3ncnc4[nH]cc(-c5ccc(F)cc5)c34)c(F)c2)OC1,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Nc1ncc(-c2cccc(N3CCOCC3=O)c2)cc1OCc1ccncc1,HPK1,not active,1000,ic50,WO2019206049A1_Original_document_20201120093115, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)C#Cc1cccc(COC2=C(N)NCC(c3cnc(C4CCCCC4)s3)=C2)c1,HPK1,medium,100,ic50,CA3097949A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
C#CC1=CC(COc2cc(-c3cnc(C4CCN(C)CC4)s3)cnc2N)CC=N1,HPK1,medium,100,ic50,CA3097949A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CC(Oc1cc(-c2cnc(C3CCN(C)CC3)s2)cnc1N)c1ccnc(C#CC(C)(C)O)c1,HPK1,medium,100,ic50,CA3097949A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(COc2cc(-c3cnc(C4CCN(C)CC4)s3)cnc2N)cc1,HPK1,not active,1000,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ncc(-c3cnc(N)c(OC(C)(C)c4ccncc4)c3)s2)CC1,HPK1,not active,1000,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ncc(-c3cnc(N)c(OCc4cccc(C#CC5(O)CCCCC5)c4)c3)s2)CC1,HPK1,not active,1000,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ncc(-c3cnc(N)c(OCc4cccc(C#CC(C)(O)C(F)(F)F)c4)c3)s2)CC1,HPK1,not active,1000,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3ccc([C@H]4CCOC4)c(N4CCNCC4)n3)c21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4cccc(N5C[C@H](N6CCC6)CC5=O)n4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4cccc(N5C[C@H](CN6CCC6)CCC5=O)n4)c4c3CNC4=O)ccnc21,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4ccnc(N5CC[C@H]6CNC[C@H]65)n4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(Nc2cnc(-c3ccnc4c3ccn4C)c3c2C(=O)NC3)nc(N2CC[C@@H]3CNC[C@@H]32)c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4cccc(N5CC6(CCN6)C5)n4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4cncc(N5CC[C@H]6CNC[C@H]65)n4)c4c3CNC4=O)ccnc21,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(Nc2cnc(-c3ccnc4c3ccn4C)c3c2C(=O)NC3)nc1N(C)C1CNC1,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)Cc1cc(Nc2ccc(-c3cnc4cc(F)ccn34)c3c2C(=O)NC3)ncc1C1(O)CCOCC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(Nc2cnc(-c3ccnc4c3ccn4C)c3c2C(=O)NC3)nc(N2CC[C@H]3CN(C)C[C@H]32)c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(Nc2cnc(-c3ccnc4c3ccn4C)c3c2C(=O)NC3)nc(N2CC[C@@H]3CNC[C@@H]32)c1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cncn4ccnc34)ncc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1C[C@@H]2CCN(c3cccc(Nc4cnc(-c5ccnc6c5ccn6C)c5c4C(=O)NC5)n3)[C@@H]2C1,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CC[C@@]12CCN(c1cccc(Nc3cnc(-c4ccnc5c4ccn5C)c4c3C(=O)NC4)n1)C2,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3ccnn4cccc34)ncc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3ccnc4cnccc34)ncc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(C)(c2cccc(Nc3cnc(-c4ccnc5c4ccn5C)c4c3C(=O)NC4)n2)CC1,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3ccnn4ccnc34)ncc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccn2c(-c3ncc(Nc4cccc(N5CC[C@H]6CNC[C@H]65)n4)c4c3CNC4=O)cnc2c1F,HPK1,medium,100,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)[C@@H]1CN(c2ccc(Nc3cnc(-c4cnc5ccccn45)c4c3C(=O)NC4)nc2)CCO1,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CC(c2cccc(Nc3cnc(-c4ccnc5c4ccn5C)c4c3C(=O)NC4)n2)C1,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4cccc(C5(C)CCNCC5)n4)c4c3CNC4=O)ccnc21,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCc2ccc(Nc3cnc(-c4ccnc5c4ccn5C)c4c3C(=O)NC4)nc2C1,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ncc(Nc4ccc5c(n4)CNCC5)c4c3CNC4=O)ccnc21,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ncc(Nc2ccc(-c3cnc4cc(F)ccn34)c3c2C(=O)NC3)c1C1CCOCC1,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cccn4ccnc34)ncc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3ccn(C4CCOCC4)n3)c21,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1nccc2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)cnc1-2,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cccc4ccnn34)ncc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3cccc(N4CCCC4=O)n3)c21,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cnccn34)ccc(Nc3cc(N4CCC(O)CC4)ccn3)c21,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3cccc(N4CC(O)C4)n3)c21,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1NC(=O)c2c(Nc3ccc(N4CCC(O)CC4)cn3)ccc(-c3cnc4ccccn34)c21,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(-n4ccc(N5CCC(O)CC5)n4)c4c3CNC4=O)ccnc21,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(-n4ccc(N5CC=C[C@@](C)(O)C5)n4)c4c3CNC4=O)ccnc21,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(-n4ccc(N5CCC[C@](C)(O)C5)n4)c4c3CNC4=O)ccnc21,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCc2cc(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)nn2CC1=O,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1NC(=O)c2c(Nc3ccc(N4CCC(O)CC4)cn3)ccc(-c3ccnc4c3ccn4C)c21,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3C(C)(C)NC4=O)ccnc21,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1NC(=O)c2c(Nc3ccc(N4CCNCC4)cn3)ccc(-c3ccnc4c3ccn4C)c21,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(N2CCC(O)CC2)cnc1Nc1ccc(-c2ccnc3c2ccn3C)c2c1C(=O)NC2,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3cnc(-c4c[nH]c5cc(OCc6ccccc6)ccc45)c4c3C(=O)NC4)nc2)CC1,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3cnc(-c4c[nH]c5nc(C(F)(F)F)ccc45)c4c3C(=O)NC4)nc2)CC1,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1nc2ccccn2c1-c1ncc(Nc2ccc(N3CCC(O)CC3)cn2)c2c1CNC2=O,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cnn2c(-c3ccc(Nc4ccc(N5CCC(O)CC5)cn4)c4c3CNC4=O)ccnc12,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3cnc4ccc(C(F)(F)F)cn34)ccc(Nc3ccc(N4CCC(O)CC4)cn3)c21,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3ccnc4ccnn34)ccc(Nc3ccc(N4CCNCC4)cn3)c21,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1cnc2nccc(-c3ccc(Nc4ccc(N5CCNCC5)cn4)c4c3CNC4=O)c21,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc2c(-c3ncc(Nc4ccc(N5CCN(C)CC5)cn4)c4c3CNC4=O)c(C)[nH]c2n1,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3c[nH]c4ccccc34)ncc(Nc3ccc(N4CC5CCC(C4)O5)cn3)c21,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(Nc3cnc(-c4cn(C)c5ncccc45)c4c3C(=O)NC4)nc2)CC1,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1NCc2c(-c3c[nH]c4ccccc34)ncc(Nc3ccc(N4CCC(F)(F)CC4)cn3)c21,HPK1,not active,1000,ic50,WO2021050964A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3n[nH]c4ccn(-c5ccc(C(=O)N(C)C)cc5)c(=O)c34)cc2)CC1,HPK1,not active,1000,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc3ncn(-c4ccccc4P(C)(C)=O)c3n1)CN(C)CC2,HPK1,not active,1000,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc3ncn(-c4ccccc4C(=O)N(C)C)c3n1)CN(C)CC2,HPK1,not active,1000,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc3ncn(-c4ccccc4)c3n1)CN(C)CC2,HPK1,not active,1000,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(-n3c(C(=O)N(C)C)cc4ccccc43)n1)CN(C)CC2,HPK1,not active,1000,ic50,WO2021000935A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(N(C)C(=O)C=C3CCC(C#N)CC3)cc2c1,HPK1,not active,1000,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3n[nH]c4ccccc34)cc2c1,HPK1,not active,1000,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C3(C(=O)Nc4ccccc4)CC3)cc2c1,HPK1,not active,1000,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(C#N)ccc1NC(=O)C(=O)Nc1cc2cc(-c3cnccc3C)cc(N)c2cn1,HPK1,not active,1000,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(NC(=O)C(=O)Nc3ccc(C(C)C)cc3Br)cc2c1,HPK1,not active,1000,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc(N)c2cnc(Nc3c(Nc4ccccc4)c(=O)c3=O)cc2c1,HPK1,not active,1000,ic50,WO2021004547A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccccc2C2CCNCC2)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1ccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2N2C[C@H](N)C[C@@H]2CO)nc1-c1c(F)cccc1OC,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(C#N)ccc2N2C[C@@H]3C[C@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COC[C@@H]1CCCN1c1ccc(F)cc1NC(=O)c1ccnc(-c2c(F)cccc2OC)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(c(-c4ccccc4)nn3C)c2N2CCC(N(C)C)CC2)n1,HPK1,medium,100,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
Fc1ccccc1-c1ccc2[nH]nc(-c3cnn(C4CCNCC4)c3)c2n1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
Cn1cc(-c2n[nH]c3ccc(-c4ccccc4F)nc23)cn1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CNC(=O)c1ccc(-c2n[nH]c3ccc(-c4ccccc4F)nc23)cc1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CCc1cn2cccc(-c3ccc4[nH]nc(-c5ccc(N6CCN(C)CC6)cc5)c4n3)c2n1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5cccc6c5ccn6C)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5cccc6c5CC(=O)N6)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5cccc6ncccc56)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5ccncc5)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5ccccc5-c5ccccc5)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CNC(=O)c1cccc(-c2ccc3[nH]nc(-c4ccc(N5CCN(C)CC5)cc4)c3n2)c1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5cccc6c5OCCO6)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5cccc6c5OCC6)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5ccccc5O)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
COc1ccccc1-c1ccc2[nH]nc(-c3ccc(N4CCN(C)CC4)cc3)c2n1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5ccccc5)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CC1OCCCC1n1cc2c(-c3ccc(N4CCN(C)CC4)cc3)n[nH]c2cc1=O,HPK1,medium,100,Ki,WO2018049191A1_Original_document_20200804051932,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cc(=O)n(Cc5ccccc5)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049191A1_Original_document_20200804051932,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cc(=O)n(C5CCCCC5)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049191A1_Original_document_20200804051932,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cc(=O)n(-c5ccccc5)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049191A1_Original_document_20200804051932,Over 100 nM
CNC(=O)c1cccc(-c2ncc3[nH]nc(-c4ccc(N5CCN(C)CC5)cc4)c3n2)c1F,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3ccc(C4(N5CCOCC5)CC4)cc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3cccc(N4CCCC4)c3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3ccc(C(=O)N(C)C)cc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3ccc(C(F)(F)F)cc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3cncnc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3ccccc3F)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(C(N)=O)c1-c1nccc(C(=O)Nc2ccc3sc(C)nc3c2N2C[C@H](N)C[C@H]2CO)n1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
CCC1(O)C(=O)NC2C=CC(c3cnc4c(c3)C3(CC3)CN4)=CC21,HPK1,medium,280.7,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
COCCn1cc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)cn1,HPK1,medium,396.96,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
N#Cc1ccc2ccn(-c3cnc4c(c3)C3(CC3)CN4)c2c1,HPK1,medium,590,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)C(=O)c1ccc2[nH]cc(-c3cnc4c(c3)C3(CC3)CN4)c2c1,HPK1,medium,373.4,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
Cn1cnnc1-c1ccc2[nH]cc(-c3cnc4c(c3)C3(CC3)CN4)c2c1,HPK1,medium,130,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
c1ccc2c(c1)nnn2-c1cnc2c(c1)C1(CC1)CN2,HPK1,medium,570,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CS(=N)(=O)c1ccc2[nH]cc(-c3cnc4c(c3)C3(CC3)CN4)c2c1,HPK1,medium,243.2,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
c1nc2c(cc1-c1c[nH]c3ccc(C4CC4)cc13)C1(CC1)CN2,HPK1,medium,289.3,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
Clc1c(-c2cnn(Cc3ccccc3)c2)cnc2c1C1(CC=CC1)CN2,HPK1,medium,603.35,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
Cc1[nH]ncc1-c1cnc2c(c1)C1(CC1)CN2,HPK1,medium,320.96,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CC(C)(O)Cn1cc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)cn1,HPK1,medium,337.3,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)C(=O)Cn1cc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)cn1,HPK1,medium,305.74,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
NC(=O)Cn1cc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)cn1,HPK1,medium,235.56,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
OCCn1cc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)cn1,HPK1,medium,208.77,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
Fc1cccc2[nH]cc(-c3cnc4c(c3)C3(CC3)CN4)c12,HPK1,medium,492.4,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
c1ccc2c(-c3cnc4c(c3)C3(CC3)CN4)c[nH]c2c1,HPK1,medium,125,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
NC(=O)CCn1cc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)cn1,HPK1,medium,160.59,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
Cc1n[nH]cc1-c1cnc2c(c1Cl)C1(CC=CC1)CN2,HPK1,medium,186.4,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
Nc1cc(-c2cnc3c(c2)C2(CC2)CN3)nc(-c2ncccn2)c1,HPK1,medium,386.6,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)C(=O)c1cc(N)cc(-c2cnc3c(c2)C2(CC2)CN3)n1,HPK1,medium,308.7,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
Nc1cc(-c2cnc3c(c2)C2(CC2)CN3)nc(N2CCOC2=O)c1,HPK1,medium,126.9,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)C(=O)CNc1ccc(-c2cnc3c(c2)C2(CC2)CN3)cn1,HPK1,medium,236.2,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
Nc1ccc(-c2cnc3c(c2)C2(CC2)CN3)nc1C(=O)N1CCC(O)C1,HPK1,medium,558.7,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
Nc1cc(-c2cnc3c(c2)C2(CC2)CN3)nc(N2CCCOC2=O)n1,HPK1,medium,215.2,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
Clc1c(-c2ccc3[nH]ccc3c2)cnc2c1C1(CC=CC1)CN2,HPK1,medium,638.25,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
Clc1c(-c2cccc3[nH]ncc23)cnc2c1C1(CC=CC1)CN2,HPK1,medium,119.83,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
Clc1c(-c2ccc3[nH]ncc3c2)cnc2c1C1(CC=CC1)CN2,HPK1,medium,375.39,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
Clc1c(-c2cccc3[nH]ccc23)cnc2c1C1(CC=CC1)CN2,HPK1,medium,629.32,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CC1(C#N)C(=O)Nc2ccc(-c3cnc4c(c3Cl)C3(CC3)CN4)cc21,HPK1,medium,216.6,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CC1(C(N)=O)C(=O)Nc2ccc(-c3cnc4c(c3Cl)C3(CC3)CN4)cc21,HPK1,medium,143.6,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
O=C1Nc2ccc(-c3cnc4c(c3Cl)C3(CC3)CN4)cc2C1(O)C1CC1,HPK1,medium,178.9,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
O=C1OCc2ccc(-c3cnc4c(c3)C3(CC3)CN4)cc21,HPK1,medium,342.3,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
Clc1c(-c2ccc3[nH]nnc3c2)cnc2c1C1(CC=CC1)CN2,HPK1,medium,251.58,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(CC#N)C(=O)C1(c2cccc(-c3cnc4c(c3Cl)C3(CC=CC3)CN4)c2)CC1,HPK1,medium,331.4,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
N#CCNC(=O)c1ccnc(-c2cccc(-c3cnc4c(c3Cl)C3(CC=CC3)CN4)c2F)c1,HPK1,medium,191.1,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
O=C(N1CCOCC1)C1(c2cccc(-c3cnc4c(c3Cl)C3(CC=CC3)CN4)c2)CC1,HPK1,medium,484.2,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
NC(=O)C1(c2cccc(-c3cnc4c(c3Cl)C3(CC=CC3)CN4)c2F)CC1,HPK1,medium,108.179,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)C(=O)C1(c2cccc(-c3cnc4c(c3Cl)C3(CC=CC3)CN4)c2)CC1,HPK1,medium,283.239,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(CN)CC2)CN3)c1F,HPK1,medium,190,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CC(C)(C)c1nnc(-c2cccc(-c3cnc4c(c3Cl)C3(CC=CC3)CN4)c2)o1,HPK1,medium,253.07,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
Clc1c(-c2ccc(Oc3ncccn3)cc2)cnc2c1C1(CC=CC1)CN2,HPK1,medium,282.59,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
O=C(c1ccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)cc1)N1CCOCC1,HPK1,medium,447.03,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
O=C(c1ccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)cc1Cl)N1CCC(O)CC1,HPK1,medium,172.72,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
Nc1ccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)c(F)c1,HPK1,medium,363.15,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
Nc1ccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)cc1,HPK1,medium,125.85,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
COCCc1ccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)cc1,HPK1,medium,435.64,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CC(=O)Nc1cccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)c1,HPK1,medium,274.94,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
N#CCCNC(=O)c1ccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)cc1,HPK1,medium,302.83,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
Clc1c(-c2ccc(COC3CCOCC3)cc2)cnc2c1C1(CC=CC1)CN2,HPK1,medium,308.42,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
OCc1cccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)c1F,HPK1,medium,477.82,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)S(=O)(=O)Nc1cccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)c1,HPK1,medium,229.83,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
OCc1ccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)c(F)c1,HPK1,medium,330.32,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
Clc1c(-c2ccc(-n3cccn3)cc2)cnc2c1C1(CC=CC1)CN2,HPK1,medium,676.4,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
O=C(NCCO)c1ccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)cc1,HPK1,medium,339.92,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CC(=O)NCCc1ccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)cc1,HPK1,medium,286,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CC(=O)NCc1ccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)cc1,HPK1,medium,112.17,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CC(=O)NCc1cccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)c1,HPK1,medium,145.22,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
O=S(=O)(Nc1cccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)c1)C1CC1,HPK1,medium,198.71,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
O=S1(=O)CCCN1c1ccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)cc1,HPK1,medium,201.36,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)C(=O)c1ccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)c(F)c1,HPK1,medium,436.23,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)C(=O)c1ccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)cc1F,HPK1,medium,267.39,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
OCC1(c2ccc(-c3cnc4c(c3Cl)C3(CC=CC3)CN4)cc2)CC1,HPK1,medium,284.98,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
O=S(=O)(c1ccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)cc1)n1cccn1,HPK1,medium,884.67,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)C(=O)c1cccc(-c2cnc3c(c2)C2(CCC(C)(C(N)=O)C2)CN3)c1F,HPK1,medium,940.95,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)C(=O)c1ccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)cc1Cl,HPK1,medium,163.1,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
N#Cc1cccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)c1,HPK1,medium,358.83,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CCNS(=O)(=O)c1ccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)cc1,HPK1,medium,315.13,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CNS(=O)(=O)c1ccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)cc1,HPK1,medium,210.17,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CCS(=O)(=O)c1ccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)cc1,HPK1,medium,299.52,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CS(=O)(=O)c1ccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)cc1,HPK1,medium,276.4,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CC(C)(O)c1ccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)cc1,HPK1,medium,829.29,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
OCc1ccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)cc1,HPK1,medium,197.73,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
O=C(c1cccc(-c2cnc3c(c2)C2(CC2)CN3)c1F)N1CCc2ccncc21,HPK1,medium,127,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
O=C(c1cccc(-c2cnc3c(c2)C2(CC2)CN3)c1F)N1CCc2ccccc21,HPK1,medium,319,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
Cc1nccn1C1CCC2(CNc3ncc(-c4ccc(N)c(C(=O)N(C)C)c4F)c(Cl)c32)C1,HPK1,medium,162.58,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
Cc1cc(C#N)nn1C1CCC2(CNc3ncc(-c4ccc(N)c(C(=O)N(C)C)c4F)c(Cl)c32)C1,HPK1,medium,103.46,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
Cc1nc(N)n(C2CCC3(CNc4ncc(-c5ccc(N)c(C(=O)N(C)C)c5F)c(Cl)c43)C2)n1,HPK1,medium,132.42,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
Cc1nc(N)nn1C1CCC2(CNc3ncc(-c4ccc(N)c(C(=O)N(C)C)c4F)c(Cl)c32)C1,HPK1,medium,109.03,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(N4CCCC4=O)C2)CN3)c1F,HPK1,medium,157.19,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CC1CN(C(=O)c2cccc(-c3cnc4c(c3)C3(CC3)CN4)c2F)C1,HPK1,medium,115.7,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C(=O)c1cccc(-c2cnc3c(c2)C2(CC2)CN3)c1F)c1cnn(C)c1,HPK1,medium,125.5,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CC(C)C1CN(C(=O)c2cccc(-c3cnc4c(c3)C3(CC3)CN4)c2F)C1,HPK1,medium,120.2,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(CN)C2)CN3)c1F,HPK1,medium,164.6,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(N4CCCC4)C2)CN3)c1F,HPK1,medium,381.43,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(N4CCOCC4)C2)CN3)c1F,HPK1,medium,479.49,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(O)(Cn4ccnc4)C2)CN3)c1F,HPK1,medium,246.86,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(O)(Cn4cncn4)C2)CN3)c1F,HPK1,medium,153.33,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2)C2(CN3)CC(C#N)C2)c1F,HPK1,medium,123.97,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2)C2(CN3)CC(CC#N)C2)c1F,HPK1,medium,120,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CC(=O)N1CC2(CNc3ncc(-c4ccc(N)c(C(=O)N(C)C)c4F)cc32)C1,HPK1,medium,915.73,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2)C2(CN3)CC(n3cncn3)C2)c1F,HPK1,medium,125.75,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2)C2(CN3)CC(O)(C(F)(F)F)C2)c1F,HPK1,medium,358.33,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CC(=O)NC1CCC2(CNc3ncc(-c4ccc(N)c(C(=O)N(C)C)c4F)c(Cl)c32)C1,HPK1,medium,207.61,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2)C2(CNC(=O)C2)CN3)c1F,HPK1,medium,658.91,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2)C2(CN3)CC(C)(O)C2)c1F,HPK1,medium,926.98,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2)C2(CN3)CC(O)C2)c1F,HPK1,medium,159.68,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(NCC(N)=O)C2)CN3)c1F,HPK1,medium,490,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)C2(CCC(N(C)CC(N)=O)C2)CN3)c1F,HPK1,medium,251.07,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
c1cc(-c2cnc3c(c2)C2(CC2)CN3)cc(-c2nnn3c2CNCC3)c1,HPK1,medium,278.559,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
O=C1NCCN1c1cccc(-c2cnc3c(c2)C2(CC2)CN3)n1,HPK1,medium,114.8,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
O=C1NCCCN1c1cccc(-c2cnc3c(c2)C2(CC2)CN3)n1,HPK1,medium,101.7,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
NS(=O)(=O)c1ccc(-c2cnc3c(c2)C2(CC2)CN3)cc1,HPK1,medium,134.67,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CC(=O)NC1CN(C(=O)c2cccc(-c3cnc4c(c3Cl)C3(CC3)CN4)c2F)C1,HPK1,medium,139.24,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
O=C(c1cccc(-c2cnc3c(c2Cl)C2(CC2)CN3)c1F)N1CCNCC1,HPK1,medium,151.364,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CC(=O)Nc1cc(C(=O)N(C)C)cc(-c2cnc3c(c2Cl)C2(CC2)CN3)c1,HPK1,medium,770.9,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
O=C1Nc2ccc(-c3cnc4c(c3)C3(CC3)CN4)cc2C1(O)C1CC1,HPK1,medium,183.8,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CNS(=O)(=O)c1cccc(-c2cnc3c(c2)C2(CC2)CN3)c1F,HPK1,medium,868.7,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)S(=O)(=O)c1cccc(-c2cnc3c(c2)C2(CC2)CN3)c1F,HPK1,medium,296.6,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CC1(O)C(=O)Nc2ccc(-c3cnc4c(c3)C3(CC3)CN4)cc21,HPK1,medium,212.4,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)C(=O)c1cc(-c2cnc3c(c2)C2(CC2)CN3)ccc1CO,HPK1,medium,258.9,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)C(=O)c1cc(CO)cc(-c2cnc3c(c2)C2(CC2)CN3)c1,HPK1,medium,521,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2)C2(CC2)CN3)c1Cl,HPK1,medium,863.1,Ki,WO2020061377A1_Original_document_20201118034029,Over 100 nM
Cn1ccc2cncc(-c3cc4cc(NC(=O)[C@@H]5C[C@@H]5F)ncc4c(N)n3)c21,HPK1,medium,101,Ki,WO2018183956A1_Original_document_20201230132016,Over 100 nM
CCc1ccncc1-c1cc2cc(NC(=O)C3=CC3)ncc2c(N)n1,HPK1,medium,545,Ki,WO2018183956A1_Original_document_20201230132016,Over 100 nM
CC(Oc1ccccn1)c1cc2cc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)ncc2c(N)n1,HPK1,medium,511,Ki,WO2018183956A1_Original_document_20201230132016,Over 100 nM
Cc1ccncc1C#Cc1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cnn(C)c3)ncc2c(N)n1,HPK1,medium,170,Ki,WO2018183956A1_Original_document_20201230132016,Over 100 nM
Cc1ccncc1-c1cc2cc(NCC(F)F)ncc2c(N)n1,HPK1,medium,345,Ki,WO2018183956A1_Original_document_20201230132016,Over 100 nM
Cc1ccncc1-c1cc2cc(Nc3cc(C4CC4)n(CCO)n3)ncc2c(N)n1,HPK1,medium,146,Ki,WO2018183956A1_Original_document_20201230132016,Over 100 nM
CCNC(=O)[C@H]1C[C@H]1C(=O)Nc1cc2cc(-c3cnccc3C)nc(N)c2cn1,HPK1,medium,110,Ki,WO2018183956A1_Original_document_20201230132016,Over 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@@H]3C(=O)N(C)C)ncc2c(N)n1,HPK1,medium,130,Ki,WO2018183956A1_Original_document_20201230132016,Over 100 nM
CCc1ccncc1-c1cc2cc(NC(=O)C3C[C@H]3C(=O)C3CC(O)C3)ncc2c(N)n1,HPK1,medium,163,Ki,WO2018183956A1_Original_document_20201230132016,Over 100 nM
CCc1ccncc1-c1cc2cc(NS(=O)(=O)C3CC3)ncc2c(N)n1,HPK1,medium,839,Ki,WO2018183956A1_Original_document_20201230132016,Over 100 nM
CCc1cc(=O)n(C)cc1-c1cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc2c(N)n1,HPK1,medium,440,Ki,WO2018183956A1_Original_document_20201230132016,Over 100 nM
Cc1c(-c2cc3cc(NC(=O)O[C@H]4CCCC[C@@H]4C#N)ncc3c(Cl)c2F)cnc2c1NCCO2,HPK1,medium,492,Ki,WO2020072627A1_Original_document_20201119122058,Over 100 nM
Cc1c(-c2cc3cc(NC(=O)OCC(F)(F)F)ncc3cc2F)cnc2c1NCCO2,HPK1,medium,205,Ki,WO2020072627A1_Original_document_20201119122058,Over 100 nM
Cc1ccncc1-c1ccc2nnc(NC(=O)C3CC3)cc2c1,HPK1,medium,510,Ki,WO2020069402A1_Original_document_20201120091428,Over 100 nM
Cc1ccncc1-c1cc(C)c2nnc(NC(=O)C3CC3)cc2c1,HPK1,medium,260,Ki,WO2020069402A1_Original_document_20201120091428,Over 100 nM
CCc1ccncc1-c1cc(N)c2nnc(NC(C)C)cc2c1,HPK1,medium,400,Ki,WO2020069402A1_Original_document_20201120091428,Over 100 nM
Nc1cc(C2CC2)cc2cc(NC(=O)C3CC3F)nnc12,HPK1,medium,600,Ki,WO2020069402A1_Original_document_20201120091428,Over 100 nM
CCc1cc(N)c2nnc(NC(=O)[C@@H]3C[C@@H]3F)cc2c1,HPK1,medium,440,Ki,WO2020069402A1_Original_document_20201120091428,Over 100 nM
N#Cc1ccncc1-c1cc(N)c2nnc(NC(=O)[C@@H]3C[C@@H]3F)cc2c1,HPK1,medium,600,Ki,WO2020069402A1_Original_document_20201120091428,Over 100 nM
Cc1ccncc1-c1cc2cc(Nc3ccc(CO)cn3)ncc2cn1,HPK1,medium,577,Ki,WO2020023551A1_Original_document_20201120101107,Over 100 nM
Cc1ccncc1-c1cc2cc(Nc3ccc(S(C)(=O)=O)cn3)ncc2cn1,HPK1,medium,291,Ki,WO2020023551A1_Original_document_20201120101107,Over 100 nM
Cc1ccncc1-c1cc2cc(Nc3cc(C(=O)N(C)C)c(N)cn3)ncc2cn1,HPK1,medium,463,Ki,WO2020023551A1_Original_document_20201120101107,Over 100 nM
COCc1c(Cl)[nH]c2ncc(-c3ccc(N)c(C(=O)N(C)C)c3F)cc12,HPK1,medium,160,Ki,WO2018167147A1_Original_document_20201120072807,Over 100 nM
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(C)CC5)nc23)ccc1C(=O)N1CC2(COC2)C1,HPK1,active,88,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCc2c(C)cc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)c(C)c5)c4n3)cc2C1,HPK1,active,86,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CCN(C)C5)nc23)ccc1C(=O)N(C)C,HPK1,active,43,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCc2c(cc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4n3)cc2C(F)F)C1,HPK1,active,71,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)CC(C)(C)O)cc4)c3n2)cc2c1CCN(C)C2,HPK1,active,65,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C[C@H](C)O)c(C)c4)c3n2)cc2c1CN(C)CC2,HPK1,active,32,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2c[nH]c3ncc(-c4cc(C)c5c(c4)CN(C)CC5)nc23)ccc1C(=O)N(C)C,HPK1,active,26,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3n2)cc2c1CCN(C)C2,HPK1,active,24,ic50,WO2021000925A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ccc(-c3cnc(N)c(OCc4ccncc4)c3)nc2)CC1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1ncc(-c2cnc(N)c(OCc3cccc(C#CC(C)(C)O)c3)c2)s1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1ncc(-c2cnc(N)c(OCc3ccncc3)c2)s1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ncc(-c2cnc(N)c(OCc3ccncc3)c2)s1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)C#Cc1cccc(COc2cc(-c3cnc(C4CCN(CC(F)(F)F)CC4)s3)cnc2N)c1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CCC(C)c1ncc(-c2cnc(N)c(OCc3cccc(C#CC(C)(C)O)c3)c2)s1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CSc1ncc(-c2cnc(N)c(OCc3cccc(C#CC(C)(C)O)c3)c2)s1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ncc(-c3cnc(N)c(OCc4ccnc(C#N)c4)c3)s2)CC1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ncc(-c3cnc(N)c(OCc4ccnc(Cl)c4)c3)s2)CC1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ncc(-c3cnc(N)c(OCc4ccc(F)cc4)c3)s2)CC1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CC(Oc1cc(-c2cnc(C3CCN(C)CC3)s2)cnc1N)c1ccncc1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ncc(-c3cnc(N)c(OCc4ccccc4)c3)s2)CC1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1ncc(-c2cnc(N)c(OCc3cncc(C#CC(C)(C)O)c3)c2)s1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(c2ncc(-c3cnc(N)c(OCc4cncc(C#CC(C)(C)O)c4)c3)s2)CC1,HPK1,medium,100,ic50,CN110396087A, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(-c3cnn(C)c3)c(Nc3ccccc3P(C)(C)=O)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCc2cc(C(F)(F)F)c(Nc3ncc(Cl)c(Nc4ccccc4P(C)(C)=O)n3)cc2C1,HPK1,medium,100,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3P(C)(C)=O)n1)CN(C)CCC2,HPK1,medium,100,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3P(C)(C)=O)n1)C(=O)N(C)CCC2,HPK1,medium,100,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1nccc(Nc3ccccc3P(C)(C)=O)n1)CN(C)CC2,HPK1,medium,100,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3P(C)(C)=O)n1)[C@@H](N(C)C)CC2,HPK1,not active,10000,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3P(C)(C)=O)n1)[C@@H](N(C)C)CCC2,HPK1,medium,100,ic50,WO2018102366A1_Original_document_20201120110353, not Ki or Kd; not used in NCI fingerprint analysis
COc1nn(C2CCNCC2)cc1-c1cnc(N)c2cc(C#N)c(-c3c(C)cccc3F)cc12,HPK1,active,50,ic50,WO2021175271A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cccc(F)c1-c1cc2c(-c3cn(C4CCNCC4)nc3C)cnc(N)c2cc1C#N,HPK1,medium,500,ic50,WO2021175271A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cccc(F)c1-c1ccc2c(N)ncc(-c3ccc(N4CCN(C)CC4)nc3)c2n1,HPK1,active,50,ic50,WO2021175271A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cccc(F)c1-c1cc2c(-c3ccc(N4CCN(C)CC4)nc3)cnc(N)c2cc1C#N,HPK1,active,50,ic50,WO2021175271A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)Oc1ccc(-c2c[nH]c3ncnc(Oc4c(F)cc(NC5=NCC(C)(CO)CO5)cc4F)c23)cc1C#N,HPK1,active,50,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(-c2c[nH]c3ncnc(Oc4c(F)cc(NC(=S)NCC5(CO)CC5)cc4F)c23)c(F)c1,HPK1,active,50,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
N#Cc1cnc2[nH]cc(C(F)(F)F)c2c1Oc1ccc(NC2=NCC(F)(CO)CO2)cc1F,HPK1,active,50,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3ccc4c(c3)[C@H](C)N(C(=O)Nc3cnc(OCCCN(C)C)c(C(F)(F)F)c3)CC4)ccnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1c2cc(Oc3ccnc4[nH]ccc34)ccc2CCN1C(=O)Nc1ccc(CN2CCNCC2)c(C(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4c(C#N)cc(Oc5ccnc6[nH]ccc56)cc4C3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc6[nH]ccc56)cc4C3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnn6cccc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4cnc(Nc5ccnc6[nH]ccc56)nc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(CC(F)F)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C(=O)N(C)C)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCNCC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnn4cc(C(=O)NC)nc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnn4cc(C(=O)NC)nc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnn4cc(C(=O)N(C)C)nc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3cnc4c(c3)CN(C(=O)Nc3ccc(CN5CC6CCC(C5)N6)c(C(F)(F)F)c3)C[C@H]4C)ccnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3cnc4c(c3)CN(C(=O)Nc3ccc(CN5C[C@H]6C[C@@H]5CN6C)c(C(F)(F)F)c3)C[C@H]4C)ccnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2cnc(O[C@H]3CCN[C@@H](C)C3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2cnc(O[C@@H]3CCN(C)C3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C)cc34)cnc21,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc(NCCO)c5)cnc4C(C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6ncc(=O)[nH]c56)cnc4C(C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]c(=O)cnc56)cnc4C(C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ncc(Oc5ncnc6[nH]c(C)cc56)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ncc(Oc5ccnc6[nH]ccc56)cc4[C@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4c(cc(F)cc4Oc4ncnn5cccc45)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(-c5ccc6cc(NC)ncc6c5)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc6[nH]ccc56)cc4C3=O)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CC4CCC3c3cc(Oc5ccnc6[nH]ccc56)ccc34)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)C3CCc4ccc(Oc5cc(NC)ncn5)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Nc5ccnc(NC)c5)cnc4C(C)C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Nc5ncnn6cccc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ncc(Oc5ncnc6[nH]c(C)cc56)cc4C3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ncc(Oc5ccnc6[nH]ncc56)cc4C3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ncc(Oc5ccnc6[nH]c(C)cc56)cc4C3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ncc(Oc5ncnc6[nH]ccc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3ccc4c(c3)[C@H](C)N(C(=O)Nc3cnc(OCCC5C=CN=C5)c(C(F)(F)F)c3)CC4)cccc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3ccc4c(c3)[C@H](C)N(C(=O)Nc3cnc(OCCN(C)C)c(C(F)(F)F)c3)CC4)ccnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3ccc4c(c3)[C@H](C)N(C(=O)Nc3cnc(OC5CCCN(C)CC5)c(C(F)(F)F)c3)CC4)ccnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3ccc4c(c3)[C@H](C)N(C(=O)Nc3cnc(OC5CN(C)C5)c(C(F)(F)F)c3)CC4)ccnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3ccc4c(c3)[C@H](C)N(C(=O)Nc3cnc(OC5CCN(C)CC5F)c(C(F)(F)F)c3)CC4)ccnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3ccc4c(c3)[C@H](C)N(C(=O)Nc3cnc(OC5CCN(C)CC5O)c(C(F)(F)F)c3)CC4)ccnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3ccc4c(c3)[C@H](C)N(C(=O)Nc3cnc(OC5CCCN(C)C5)c(C(F)(F)F)c3)CC4)ccnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3ccc4c(c3)[C@H](C)N(C(=O)Nc3cnc(OC5CCN(C)CC5C)c(C(F)(F)F)c3)CC4)ccnc2[nH]1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1c2cc(Oc3ccnc4[nH]ccc34)ccc2CCN1C(=O)Nc1ccc(CN2CCN(C3COC3)CC2)c(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc6[nH]ccc56)cc4[C@@H]3C)cc2C(F)(F)F)C(=O)C1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCC(Oc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc6[nH]ccc56)cc4[C@@H]3C)cc2C(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1c2cc(Oc3ccnc4[nH]ccc34)ccc2CCN1C(=O)Nc1ccc(OC2CCN(C)CC2)c(C(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc(C(N)=O)c5)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5ccnc(C#N)c5)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4cc(F)c(Oc5ncnn6cccc56)cc4C3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4cc(F)c(Oc5ccnn6cccc56)cc4C3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCC1c2cc(Oc3ccnc4[nH]ccc34)ccc2CCN1C(=O)Nc1ccc(CN2CCN(CC)CC2)c(C(F)(F)F)c1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C#Cc1cc2c(cc1Oc1ccnc3[nH]ccc13)C(C)N(C(=O)Nc1ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c1)CC2,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4nc(C)c(Oc5ccnc6[nH]ccc56)cc4C3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4cc(F)c(Oc5ccnc6[nH]ccc56)cc4C3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4c(C)cc(Oc5ccnc6[nH]ccc56)cc4C3C)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5cc(C)nc6[nH]ccc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(CC2CC=C(NC(=O)N3CCc4ccc(Oc5c(Cl)cnc6[nH]ccc56)cc4C3)C=C2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5c(C)cnc6[nH]ccc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Oc5cn[nH]c5)cc4C3)cc2C(F)(F)F)CC1,HPK1,medium,500,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN2c3ccc(-c4cnc5[nH]cc(-c6ccc(C(=O)N7CC(N(C)C)C7)cc6)c5n4)cc3OCC2C1,HPK1,not active,35600,ic50,WO2021213317A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(F)c(F)c1-c1cc2c(-c3ccc4c(c3)OCC3CN(C)CCN43)n[nH]c2cn1,HPK1,active,10,ic50,WO2021213317A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN2c3ccc(-c4n[nH]c5cnc(-c6cccc(F)c6F)cc45)cc3OCC2C1,HPK1,active,10,ic50,WO2021213317A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1-c1cc2c(-c3ccc4c(c3)OCC3CN(C)CCN43)n[nH]c2cc1C#N,HPK1,not active,17400,ic50,WO2021213317A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN2c3ccc(-c4n[nH]c5cc(C#N)c(-c6c(F)cc(C(=O)N7CC(N(C)C)C7)cc6F)cc45)cc3OCC2C1,HPK1,not active,31800,ic50,WO2021213317A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CNCc1cc(F)c(-c2cc3c(-c4ccc5c(c4)OCC4CN(C)CCN54)n[nH]c3cc2C#N)c(F)c1,HPK1,not active,11800,ic50,WO2021213317A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(F)c(F)c1-c1cc2c(-c3ccc4c(c3)OCC3CN(C)CCN43)n[nH]c2cc1C#N,HPK1,not active,23600,ic50,WO2021213317A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1cc2c(-c3ccc4c(c3)OCC3CN(C)CCN43)n[nH]c2cc1C#N,HPK1,not active,17800,ic50,WO2021213317A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cccc(F)c1-c1cc2c(-c3cnc(C4CCNCC4)s3)cnc(N)c2cc1C#N,HPK1,active,50,ic50,WO2021175271A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
O=C(c1ccc(-c2c[nH]c3ncnc(Oc4c(F)cc(NC5=NCC6(CC6)CO5)cc4F)c23)cc1)N(CCO)CCO,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1nnc(-c2c[nH]c3ncnc(Oc4c(F)cc(NC5=NCC(C)(CO)CO5)cc4F)c23)o1,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CNCc1ccc(-c2c[nH]c3ncnc(Oc4c(F)cc(NC5=NCC(C)(CO)CO5)cc4F)c23)c(F)c1,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCN(C)C(=O)c1ccc(-c2c[nH]c3ncnc(Oc4c(F)cc(NC5=NCC(C)(CO)CO5)cc4F)c23)cc1,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
OCC1(F)CN=C(Nc2cc(F)c(Oc3ncnc4[nH]cc(C5CC5)c34)c(F)c2)OC1,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Fc1cc(NC2=NCC3(CC3)CO2)cc(F)c1Oc1ncnc2[nH]cc(C(F)(F)F)c12,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
OCC1(F)CN=C(Nc2cc(F)c(Oc3ncnc4[nH]cc(C(F)(F)F)c34)c(F)c2)OC1,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCCC(Nc2cc(F)c(Oc3ncnc4[nH]cc(-c5ccc(F)cc5)c34)c(F)c2)C1,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(C(=O)Nc2cc(F)c(Oc3ncnc4[nH]cc(-c5ccc(F)cc5)c34)c(F)c2)CC1,HPK1,not active,1000,ic50,WO2021175270A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc(N)c(O[C@@H](C)c3c(Cl)ccc(C(=O)NC4CC4)c3Cl)n2)cc2c1CCN(C)C2,HPK1,not active,2680,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc(N)c(OCC3CCN(C)CC3)n2)cc2c1CCN(C)C2,HPK1,not active,3270,ic50,WO2021032148A1（HPK1）, not Ki or Kd; not used in NCI fingerprint analysis
CCCN(C)C(=O)c1cnc(Nc2ccc3c(c2)C(C)(C)OC3=O)nc1N[C@H](CO)c1ccccc1,HPK1,not active,2000,ic50,"BMS-Discovery of Orally Active Isofuranones as Potent, Selective Inhibitors of Hematopoetic Progenitor Kinase 1", not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1cc2c(cn1)cnn2-c1ccccc1,HPK1,not active,1050,ic50,Merck-Identification of Potent Reverse Indazole Inhibitors for HPK1, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccncc1-c1ccc2cnn(-c3ccnc(N4CCOCC4)c3)c2c1,HPK1,not active,2302,ic50,Merck-Identification of Potent Reverse Indazole Inhibitors for HPK1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cccc(F)c1-c1ccc2cnn(-c3ccc(N4CCN(C)CC4)cc3)c2c1,HPK1,not active,1470,ic50,Merck-Identification of Potent Reverse Indazole Inhibitors for HPK1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(F)c1-c1cc2c(cn1)cnn2-c1cnn(C)c1,HPK1,not active,1090,ic50,Merck-Identification of Potent Reverse Indazole Inhibitors for HPK1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CN(c2cc(-n3ncc4ccc(-c5cnn6c5OCCC6)cc43)ccn2)C[C@@H](C)N1C,HPK1,not active,1460,ic50,Merck-Identification of Potent Reverse Indazole Inhibitors for HPK1, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CC(C)c4ccc(Oc5ccnc6[nH]ccc56)cc4[C@@H]3C)cc2C(F)(F)F)CC1,HPK1,not active,10000,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCN(CC(F)(F)F)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C(=O)N(C)C)cc34)cnc21,HPK1,not active,10000,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1CN(C(=O)Nc2ccc(CN3CCNCC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnn4cc(C(=O)N(C)C)nc34)cnc21,HPK1,not active,5000,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCNCC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnn4cc(C(=O)N(C)C)nc34)cnc21,HPK1,not active,5000,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnn4cc(C(=O)N(C)C)nc34)cnc21,HPK1,not active,5000,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3cnc4c(c3)CN(C(=O)Nc3ccc(CN5C[C@@H]6C[C@H]5CN6C)c(C(F)(F)F)c3)C[C@H]4C)ccnc2[nH]1,HPK1,not active,5000,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1CN(C(=O)Nc2cnc(O[C@H]3CCN(C)C3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C)cc34)cnc21,HPK1,not active,10000,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCC1CN(C(=O)Nc2ccc(CN3CCN(CC)CC3)c(C(F)(F)F)c2)Cc2cc(Oc3ccnc4[nH]c(C(C)OC)cc34)cnc21,HPK1,not active,5000,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]c(C)nc56)cnc4C(C)C3)cc2C(F)(F)F)CC1,HPK1,not active,5000,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5cc(N)ncc5F)cnc4C(C)C3)cc2C(F)(F)F)CC1,HPK1,not active,5000,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3Cc4cc(Oc5ccnc6[nH]nnc56)cnc4C(C)C3)cc2C(F)(F)F)CC1,HPK1,not active,10000,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ncc(Oc5cccc6[nH]ccc56)cc4C3C)cc2C(F)(F)F)CC1,HPK1,not active,10000,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ncc(Oc5ncnc6[nH]c(C)cc56)cc4[C@H]3C)cc2C(F)(F)F)CC1,HPK1,not active,5000,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2c(Oc3ccc4c(c3)[C@H](C)N(C(=O)Nc3cnc5c(c3)CCCN5C3CCN(C)CC3)CC4)ccnc2[nH]1,HPK1,not active,5000,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
CCN1CCN(Cc2ccc(NC(=O)N3CCc4ccc(Sc5ncnn6cccc56)cc4C3)cc2C(F)(F)F)CC1,HPK1,not active,5000,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1c2cc(Oc3ccnc4[nH]ccc34)ccc2CCN1C(=O)Nc1cnc(Oc2ccncc2)c(C(F)(F)F)c1,HPK1,not active,5000,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1c2cc(Oc3ccnc4[nH]ccc34)ccc2CCN1C(=O)Nc1ccc(OC2CCN(C)CC2)c(C(F)(F)F)n1,HPK1,not active,5000,ic50,WO2019200120A1_Original_document_20201127092731, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccccc1-c1c[nH]c2ncc(-c3cc(N)c(N4CCN(C)CC4)c(C(=O)N(C)C)c3)cc12,HPK1,not active,1880,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(-n2cnc3[nH]nc(-c4ccc(N5CCN(C)CC5)cc4)c3c2=O)cc1,HPK1,not active,6365,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)ccc1N1CCC(O)CC1,HPK1,not active,9582,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(=O)N(C)C)cc4)c3c2)cc(C)c1C1(O)CCN(C)CC1,HPK1,not active,2716,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc3[nH]cc(C(=O)Nc4ccc(C(=O)N(C)C)cc4)c3c2)cc(C)c1N1CCN(C)CC1,HPK1,not active,1797,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cnc(N)c(C(=O)Nc3ccc(C(=O)N(C)C)cc3)c2)cc(C)c1N1CCN(C)CC1,HPK1,not active,5908,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2C(=O)N(C)C)CC1,HPK1,not active,1756,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(CCc2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4c3)cc2)cc1,HPK1,not active,2584,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(CCc2ccc(-c3cnc4[nH]cc(-c5ccc(C(=O)N(C)C)cc5)c4n3)cc2)cc1,HPK1,not active,7703,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccccc1-c1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCN(C)CC5)cc4)nc23)cc1,HPK1,not active,1162,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(c2ccc(-c3cnc4[nH]cc(-c5ccc(-c6ccccc6F)cc5)c4n3)cc2)CC1,HPK1,not active,5212,ic50,WO2019238067A1_Original_document_20201119102351, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(n2cc3c(-c4cnc5[nH]cc(-c6ccc(C(=O)N(C)C)cc6)c5c4)cccc3n2)CC1,HPK1,not active,6036,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCCc2c(cccc2-c2ccc3[nH]cc(-c4cccc5c4CCCN(C)C5=O)c3c2)C1=O,HPK1,not active,1437,ic50,WO2020103896A1_Original_document_20201118034443, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(NC(=O)c2ccnc(-c3c(F)cccc3OC)n2)c(N2CCC[C@@H](N)C2)c2cnn(C)c12,HPK1,medium,500,Ki,WO2019164847A1_Original_document_20201120080910,Over 100 nM
COc1cccc(F)c1C1=NC=C2NN=C(c3ccccc3C)C2N1,HPK1,medium,500,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CC(C)N1CCc2cc(Nc3cc4cc(C(C)n5ccccc5=O)nc(N)c4cn3)nn2CC1=O,HPK1,not active,1644,Ki,WO2018183956A1_Original_document_20201230132016,Over 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)Nc3ccccc3C#N)ncc2c(N)n1,HPK1,not active,1500,Ki,WO2018183956A1_Original_document_20201230132016,Over 100 nM
Cc1ccncc1-c1cc2cc(NC3CCNC3)ncc2c(N)n1,HPK1,not active,2400,Ki,WO2018183956A1_Original_document_20201230132016,Over 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)C(C)(C)O)ncc2c(N)n1,HPK1,not active,2030,Ki,WO2018183956A1_Original_document_20201230132016,Over 100 nM
COC(C)(C)C(=O)Nc1cc2cc(-c3cnccc3C)nc(N)c2cn1,HPK1,not active,4080,Ki,WO2018183956A1_Original_document_20201230132016,Over 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)C(C)(C)C#N)ncc2c(N)n1,HPK1,not active,5540,Ki,WO2018183956A1_Original_document_20201230132016,Over 100 nM
CC[C@H]1[C@H](C(=O)Nc2cc3cc(-c4c[n+]([O-])ccc4C)c(F)cc3cn2)[C@H]1c1cnn(C)c1,HPK1,not active,2000,Ki,WO2020072627A1_Original_document_20201119122058,Over 100 nM
CC[C@@H]1[C@H](C(=O)Nc2cc3cc(-c4c[n+]([O-])ccc4C)c(F)cc3cn2)[C@H]1c1cnn(C)c1,HPK1,not active,1284,Ki,WO2020072627A1_Original_document_20201119122058,Over 100 nM
CCc1ccncc1-c1cc(N)c2nnc(NC3CCOC3)cc2c1,HPK1,not active,2600,Ki,WO2020069402A1_Original_document_20201120091428,Over 100 nM
Cc1cc(Nc2cc3cc(C4CC4)ncc3cn2)ncn1,HPK1,not active,2000,Ki,WO2020023551A1_Original_document_20201120101107,Over 100 nM
Cc1cc2cc(-c3ccc(N)c(C(=O)N(C)C)c3)cnc2[nH]1,HPK1,not active,1300,Ki,WO2018167147A1_Original_document_20201120072807,Over 100 nM
O=C1COCCN1c1cccc(-c2cnc3[nH]c(CO)c(C(F)(F)F)c3c2)c1,HPK1,not active,1700,Ki,WO2018167147A1_Original_document_20201120072807,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5cccc6c5CCC6NCc5ccccc5)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5cccc(NS(C)(=O)=O)c5F)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CNC(C)c1cc(C)c(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1ccc(-c2n[nH]c3cnc(-c4c(F)cccc4OC)nc23)cc1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
Cn1cc(C(=O)Nc2cc(F)c(-c3cc4c(-c5cnn(C)c5)n[nH]c4cn3)c(F)c2)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CC(C)NCc1cccc(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c1C(F)(F)F,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(S(C)(=O)=O)cc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
CNCCc1cc(F)c(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(nc(C)n3[C@H]3CCOC3)c2N2CCC[C@H]2CN)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
Cn1cc(-c2n[nH]c3cnc(-c4c(F)cc(CNCCO)cc4F)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNC(C)c1cc(F)c(-c2ncc3[nH]nc(-c4cnn(C)c4)c3n2)c(F)c1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(ccn3C)c2N2CCC[C@@H]2CN)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
Cc1ccncc1-c1cc2c(NC(=O)c3ccc(N4CCN(C)CC4)cc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018152220A1_Original_document_20201120090908,Over 100 nM
CC(=O)Nc1ccccc1-c1ccc2[nH]nc(-c3ccc(N4CCN(C)CC4)cc3)c2n1,HPK1,medium,500,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CNC1CCCc2c1cc(F)c(-c1ncc3[nH]nc(-c4ccc(N5CCOCC5)nc4)c3n1)c2F,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(ccn3Cc3ccncc3)c2N2C[C@@H]3C[C@H]2CN3)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3ccc(N4CCN(C)CC4)cc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4cnoc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(N5CCC(O)C5)nc4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cc1ccccc1-c1ncc2[nH]nc(-c3ccc(N4CCN(C)CC4)cc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
Cn1cc(-c2n[nH]c3cnc(-c4c(F)cc(OCC5CCN5)cc4F)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(F)c(-c2ccc3[nH]nc(-c4ccc(N5CCN(C)CC5)cc4)c3n2)c(F)c1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
Cc1cc(CNC(C)C)cc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
NC1CCc2cc(F)c(-c3ncc4[nH]nc(-c5ccc(N6CCOCC6)nc5)c4n3)c(F)c21,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COC1CN(Cc2cc(C)c(-c3cc4c(-c5cnn(C)c5)n[nH]c4cn3)c(F)c2)C1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CC(C)NCc1cc(F)c(-c2cc3c(NC(=O)c4ccc(F)c(N5CCN(C)CC5)c4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cc1cc(CNC2CC2)cc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cc1c(-c2cc3c(NC(=O)c4ccc(N5CCN(C)CC5)cc4)n[nH]c3cn2)cnn1C,HPK1,medium,100,Ki,WO2018152220A1_Original_document_20201120090908,Over 100 nM
COc1ccncc1-c1ncc2[nH]nc(-c3ccc(N4CCN(C)CC4)nc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(ncn3[C@@H]3CCOC3)c2N2CCC[C@H]2CN)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
CNC1CCCc2c1ccc(F)c2-c1ncc2[nH]nc(-c3ccc(N4CCN(C)CC4)nc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CNC1CCc2c(-c3ccc4[nH]nc(-c5ccc(N6CCN(C)CC6)cc5)c4n3)cccc21,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3cnn(-c4ccccc4)c3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CN(C)CC(=O)Nc1cc(F)c(-c2ncc3[nH]nc(-c4cnn(C)c4)c3n2)c(F)c1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2N2CC3(CC3)NC[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(N5CC(CO)C5)nc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
CCN1CCN(c2ccc(-c3n[nH]c4cnc(-c5c(F)cccc5OC)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cc(NC(=O)CN2CCCC2)cc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cn1cc(-c2n[nH]c3cnc(-c4c(F)cc(C5CCCN5)cc4C(F)(F)F)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cn1cc(-c2n[nH]c3cnc(-c4c(F)cc(CNc5ccccn5)cc4F)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cc(=O)n(-c5cccc6c5OCCO6)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049191A1_Original_document_20200804051932,Over 100 nM
CN1CCN(c2ncc(-c3n[nH]c4cnc(-c5c(F)cc(CC#N)cc5F)nc34)cn2)CC1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
Cc1cc(C2CCCCN2)cc(F)c1-c1cc2c(-c3cnn(C4CC4)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cc(=O)n(C5CCOC5)cc34)cc2)CC1,HPK1,medium,500,Ki,WO2018049191A1_Original_document_20200804051932,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3ccn(C)n3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cc1cc(C2CCCN2)cc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5cccc6[nH]ncc56)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cnc(-c5cccc(C(N)=O)c5F)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
Cn1c(-c2ccccc2C#N)nc2c(N3C[C@H](N)C[C@H]3CO)c(NC(=O)c3ccnc(-c4c(F)cccc4F)n3)ccc21,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3ccc(C(=O)NC4CCCC4)cc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CNC1CCc2cc(F)c(-c3cc4c(-c5cnn(C)c5)n[nH]c4cn3)c(F)c2C1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1cc2c(-c3cccc(C4CCN(C)CC4)n3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cnc(-c5c(F)cc6c(c5F)CCCC6N)cc34)cn2)CC1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5cncnc5)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CNCc1ccc(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c(C)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNC(C)c1cc(C)c(-c2cc3c(-c4cnn(C5CC5)c4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(nc(C)n3C)c2N2C[C@H](N)C[C@H]2CO)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4cnn(C(C)C)c4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3cccc(N4CCNC(=O)C4)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1cc2c(-c3ccc(N4CCN(C)CC4)cc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(F)c(-c2cc3c(-c4ccc(N5CCC(O)CC5)nc4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3cccc(C#N)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3ccc(N4CCN(S(C)(=O)=O)CC4)cc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cn1c(-c2ncccc2F)nc2c(N3C[C@H](N)C[C@H]3CO)c(NC(=O)c3ccnc(-c4c(F)cccc4F)n3)ccc21,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3cc(F)cc(F)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CCc1ccc(C(=O)Nc2n[nH]c3cnc(-c4c(F)cccc4OC)cc23)cc1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cc1cccc(F)c1-c1nc2c(-c3cnn(C)c3)n[nH]c2cc1C#N,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CNCc1ccc(F)c(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c1F,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3ccc(CN)cc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
Cc1c(-c2cc3c(NC(=O)c4ccc(N5CCC(F)(F)C5)cc4)n[nH]c3cn2)cnn1C,HPK1,medium,100,Ki,WO2018152220A1_Original_document_20201120090908,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3cccc(F)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CCNCc1cc(C)c(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCCc1ccc(F)c(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c1F,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(nc(C)n3C)c2N2CCC[C@H]2CN)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3ccc(N4CCN(C)C(=O)C4)cc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
NC1CCCc2c1cc(F)c(-c1ncc3[nH]nc(-c4ccc(N5CCOCC5)nc4)c3n1)c2F,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CC(C)NCc1cc(F)c(-c2cc3c(C(=O)Nc4ccc(N5CCN(C)CC5)cc4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3sc(C)nc3c2N2C[C@H](NC(C)=O)C[C@H]2CO)n1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
N#Cc1ccccc1-c1nc2c(N3C[C@H](N)C[C@H]3CO)c(NC(=O)c3ccnc(-c4c(F)cccc4F)n3)ccc2n1C1CC1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3ccc(C)cc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3ccccc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4cnn(C)c4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3ccsc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CCN(C)c1cccc(-c2n[nH]c3cnc(-c4c(C)cc(CNC)cc4F)cc23)n1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(F)c(-c2ncc3[nH]nc(-c4cnc(N5CCOCC5)c(C#N)c4)c3n2)c(F)c1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5cccnc5)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
Cc1cc(CNCc2cn(C)cn2)cc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3cccc(N4CCOCC4)c3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(Cl)c1-c1cc2c(-c3ccc(N4CCN(C)CC4)cc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cc1cc(CNCC(F)(F)F)cc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNC1CCc2c1cc(F)c(-c1ncc3[nH]nc(-c4cnc(N5CCN(C)CC5)nc4)c3n1)c2F,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CNCc1cc(C)c(-c2ncc3[nH]nc(-c4ccc(N5CCN(C)CC5)cc4)c3n2)cn1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3ccc(F)cc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3ccc(F)c(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ccc(C(=O)Nc3n[nH]c4cnc(-c5c(F)cc(NC(=O)CN6CCCC6)cc5F)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cc1cc(C2CCCCN2)cc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(S(C)(=O)=O)cc2N2C[C@H](N)C[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CNC(=O)c1cncc(-c2ncc3[nH]nc(-c4ccc(N5CCN(C)CC5)cc4)c3n2)c1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2N2C[C@H](C)NC[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
Cn1cc(-c2n[nH]c3cnc(-c4c(F)cc(NC(=O)Cc5cccnc5)cc4F)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cc1cc2c(c(F)c1-c1ncc3[nH]nc(-c4ccc(N5CCN(C)CC5)nc4)c3n1)CNCC2,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
Cn1cc(-c2n[nH]c3cnc(-c4c(F)cc(OC(=O)N5CCOCC5)cc4F)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CCN1CCN(c2ccc(-c3n[nH]c4cnc(-c5c(F)cc(CNC)cc5C(F)(F)F)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
Cn1c(-c2ccncc2F)nc2c(N3C[C@H](N)C[C@H]3CO)c(NC(=O)c3ccnc(-c4c(F)cccc4F)n3)ccc21,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5cccc(F)c5F)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CNCc1cccc(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c1C,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(C3CCOCC3)cc2N2C[C@H](N)C[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
Cn1cc(-c2n[nH]c3cnc(-c4c(F)cc(OCc5ccncc5)cc4F)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3c(C)nn(C)c3C)nc2N2C[C@H](N)C[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccnc1-c1nc2c(N3C[C@H](N)C[C@H]3CO)c(NC(=O)c3ccnc(-c4c(F)cccc4F)n3)ccc2n1C,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3ccc(N4CCCCC4)cc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CN(C)C(=O)Oc1cc(F)c(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2N2C[C@H](N)C[C@@H]2CO)ccc1C#N,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CNCc1ccc(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c(C(F)(F)F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN(C)c1ncc(-c2n[nH]c3cnc(-c4c(F)cc5c(c4F)CNCC5)nc23)cn1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(Cl)cc2N2C[C@H](N)C[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cnc(-c5c(F)ccc6c5CCNC6)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CNCc1cc(F)c(-c2cc3c(-c4ccnc(N5CCN(C)CC5)c4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5cccn6ccnc56)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CN1CCN(Cc2ccc(-c3n[nH]c4cnc(-c5c(F)ccc6c5CCNC6)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
Cc1cc(C2CCCN2C)cc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(cnn3C)c2C(C)CCO)n1,HPK1,medium,100,Ki,US2019256500A1_Original_document_20201126122546,Over 100 nM
CNCc1cc(F)c(-c2cc3c(-c4ccc(N5CCOCC5)nc4)n[nH]c3cn2)c(C(F)(F)F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3cnn(C)c3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5ccccc5F)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(ccn3CC3CCCCO3)c2N2C[C@@H]3C[C@H]2CN3)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2N2C[C@@]3(CO)C[C@@H]2CN3C)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3sc(C)nc3c2N2CCC(c3ccccn3)C2)n1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
CNCc1ccc(F)c(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c1C(F)(F)F,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(nc(C)n3Cc3cnn(C)c3)c2N2CC[C@H](N)C2)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
CCNCc1ccc(F)c(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c1C,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cc1ccncc1-c1cc2c(NC(=O)c3ccc(N4CCCC(N)C4)cc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018152220A1_Original_document_20201120090908,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3ccc(N4CCOCC4)cc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
Fc1cc2c(c(F)c1-c1ncc3[nH]nc(-c4ccc(OC(F)F)nc4)c3n1)CNCC2,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3ncccc3C#N)cc2N2C[C@H](N)C[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccccc2N2C[C@H](N)C[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4cnn(C5CCOCC5)c4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3cccc(CN4CCN(C)CC4)c3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2N2C[C@@H](C)NC[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CN1CCN(c2ncc(-c3n[nH]c4cnc(-c5c(F)cc6c(c5F)CNCC6)nc34)cn2)CC1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5cncc(-c6ncco6)c5)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
Cc1cccc(F)c1-c1ncc2[nH]nc(-c3ccc(N4CCC(C#N)CC4)cc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
Cc1c(CN2CC(C)(C)C2)ccc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5cccc(C(=O)NCc6ccncc6)c5F)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cnc(-c5c(F)cc(F)cc5F)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ccc(C(=O)Nc3n[nH]c4cnc(-c5c(F)cccc5C(F)(F)F)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(F)c(-c2ncc3[nH]nc(-c4ccnc(N5CCOCC5)c4F)c3n2)c(F)c1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3ccc(N4CCN(C(C)=O)CC4)nc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3cccnc3C)cc2N2C[C@H](N)C[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CNC(=O)c1ccc(-c2n[nH]c3cc(C#N)c(-c4c(C)cccc4F)nc23)cn1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3ccc(N4CCN(C)CC4)cc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cn1cc(-c2n[nH]c3cnc(-c4c(F)cc(NC(=O)CN5CCC5)c(F)c4F)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1cc2c(-c3cnc(N4CCOCC4)s3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cnc(-c5c(Cl)cccc5C(F)(F)F)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cc1ccccc1-c1ccc2[nH]nc(-c3ccc(N4CCN(C)CC4)cc3)c2n1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
Cc1cccc(F)c1-c1cc2c(NC(=O)c3ccc(N4CCN(C)CC4)cc3NC3CCC(C#N)C3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(C(C)(C)O)nc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
Cc1c(CNCC2(C)CC2)ccc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3ccc(N4CCNCC4)nc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
Cc1cccc(F)c1-c1ncc2[nH]nc(-c3ccc(N4CCNCC4)cc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cnc(-c5cccc6c5CCNC6)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3ccc(CN4CCOCC4)cc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(C(=O)N(C)C)c(F)c4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
Cc1cccc(F)c1-c1cc2c(NC(=O)c3ccc(N4CCN(C)CC4)cc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
N#Cc1cnc(N2CCCC2)cc1-c1ccc(NC(=O)c2ccnc(-c3c(F)cccc3F)n2)c(N2C[C@H](N)C[C@@H]2CO)c1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
Cc1cccc(F)c1-c1nc2c(-c3cnc(N4CCOCC4)nc3)n[nH]c2cc1C#N,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
Cc1cccc(C)c1-c1cc2c(-c3ccc(N4CCN(C)CC4)cc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CC(C)NCc1cc(F)c(-c2cc3c(NC(=O)c4cccc(N5CCN(C)CC5)c4F)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ncc(-c3n[nH]c4cnc(-c5c(F)cc(CC#N)cc5F)cc34)cn2)CC1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4cccc(N5CCOCC5)n4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNC1CCc2c1cc(F)c(-c1ncc3[nH]nc(-c4ccc(N5CCOCC5)nc4)c3n1)c2F,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5cccc(N(C)C)c5)nc34)cc2)CC1,HPK1,medium,500,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cnc(-c5c(F)ccc6c5CCCC6N)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(ccn3C)c2N2CCNC[C@H]2C)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
Cc1nc2c(N3CCC[C@H]3CN)c(NC(=O)c3ccnc(-c4c(F)cccc4F)n3)ccc2n1C,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3ccc(Br)cc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3ccc(C4CCOCC4)cc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(nc(C)n3C)c2N2C[C@H]3C[C@@H]2CN3)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5cccc6c5CCC6N)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
O=C(Nc1ccccc1)c1ccc(-c2n[nH]c3ccc(-c4ccccc4F)nc23)cc1,HPK1,medium,500,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CNC1CCc2c1cc(C)c(-c1cc3c(-c4cnn(C)c4)n[nH]c3cn1)c2F,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3ccc(C(=O)N4CCOCC4)cc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(OCc3ccccc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(nc(C(C)C)n3C)c2N2C[C@@H]3C[C@H]2CN3)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
CNC(=O)c1ccc(-c2n[nH]c3cnc(-c4c(F)ccc5c4CCCC5NC)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4cccc(OC)c4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
Cc1cc(CNCc2cocn2)cc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2N2C[C@H](N)C[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3ccc(C4CC4)cc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CN(c1c(NC(=O)c2ccnc(-c3c(F)cccc3F)n2)ccc2c1nc(-c1c(F)cncc1F)n2C)[C@@H]1CCCNC1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
CCOc1cccc(F)c1-c1cc2c(-c3ccc(N4CCN(C)CC4)cc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNC(=O)c1cn(-c2n[nH]c3cnc(-c4c(F)cccc4OC)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3cccc(Br)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cn1cc(-c2n[nH]c3cnc(-c4c(F)cc(NC(=O)CN5C6CCC5CC6)cc4F)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)ccc2N2CCOCC2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(NC(C)=O)cc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3ccc(N4CCOCC4)nc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cnc(-c5c(F)cccc5Cl)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1cccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2N2C[C@H](N)C[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COCc1nc2c(N3CCC[C@H]3CN)c(NC(=O)c3ccnc(-c4c(F)cccc4OC)n3)ccc2n1C,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3cccc(N4CCNCC4)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(nc(-c4ccnn4C)n3C)c2N2CCC[C@H]2CN)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(/C=C/c3ccc(N4CCN(C)CC4)cc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CNCc1cc(F)c(-c2ncc3[nH]nc(-c4ccc(N5CCCCC5)nc4)c3n2)c(C(F)(F)F)c1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
Cn1cc(-c2n[nH]c3cnc(-c4c(F)cc(NC(=O)CN5CCCC5)cc4F)nc23)cn1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3sc(C)nc3c2N2C[C@H](NC3CCOCC3)C[C@H]2CO)n1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
Cc1c(CNC(C)C)ccc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(C(=O)c2ccc(-c3n[nH]c4ccc(-c5ccccc5F)nc34)cc2)CC1,HPK1,medium,500,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CO[C@H]1C[C@H](NCc2ccc(F)c(-c3cc4c(-c5cnn(C)c5)n[nH]c4cn3)c2C)C1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5cnc6cnn(C)c6c5)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
Cn1cc(-c2n[nH]c3cnc(-c4c(F)ccc(NC(=O)C5CCC5)c4F)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cnc(-c5c(F)cc6c(c5F)C(O)CC6)cc34)cn2)CC1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
N#CC1(c2ccc(NC(=O)c3ccnc(-c4c(F)cccc4F)n3)c(N3C[C@H](N)C[C@@H]3CO)c2)CC1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3ccc(N4CCN(C5CC5)C(=O)C4)cc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1ccc(-c2ncc3[nH]nc(-c4ccc(N5CCN(C)CC5)cc4)c3n2)c2c1CNCC2,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CNC(=O)c1cccc(-c2ccc3[nH]nc(-c4ccc(N5CCN(C)CC5)cc4)c3n2)c1F,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(nc(-c4ccncc4F)n3C)c2N2C[C@@H]3C[C@H]2CO3)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(N3CCC3)cc2N2C[C@H]3C[C@@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1cc2c(NCc3ccc(N4CCN(C)CC4)cc3)n[nH]c2cn1,HPK1,medium,500,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(F)c(-c2cc3c(-c4ccc(N5CCN(C)CC5)nc4)n[nH]c3cn2)c(C(F)(F)F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CS(=O)(=O)N1CCC(n2cc(-c3n[nH]c4ccc(-c5ccccc5F)nc34)cn2)CC1,HPK1,medium,500,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CC(C)N1CC(NCCc2cc(F)c(-c3cc4c(-c5cnn(C)c5)n[nH]c4cn3)c(F)c2)C1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cn1cc(-c2n[nH]c3cnc(-c4c(F)cc(NC(=O)CN5CCCC5)cc4Cl)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(nc(C)n3Cc3ccncc3)c2N2CC[C@H](N)C2)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)ccc2N2C[C@H](N)C[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
Cc1cc(NC(=O)CN2C[C@H]3CC[C@@H]2C3)ccc1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(nc(-c4ccncc4F)n3C)c2N2CCC[C@H]2CN)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
Cn1cc(-c2n[nH]c3cnc(-c4c(F)cc(NC(=O)CC5CCCC5)cc4F)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COCCn1c(C)nc2c(N3CCC[C@H]3CN)c(NC(=O)c3ccnc(-c4c(F)cccc4OC)n3)ccc21,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
Cn1cc(-c2n[nH]c3cnc(-c4c(F)cc(NC(=O)CN5CCCC5)cc4F)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5cnn6ccccc56)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CC(c1ccccc1)n1cc2c(-c3ccc(N4CCN(C)CC4)cc3)n[nH]c2cc1=O,HPK1,medium,100,Ki,WO2018049191A1_Original_document_20200804051932,Over 100 nM
CC(C)NCc1ccc(F)c(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c1F,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3ccc(N4CCNC(=O)C4)cc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3sc(C(C)C)nc3c2N2C[C@@H](N)C[C@H]2CO)n1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
Cc1cccc(F)c1-c1cc2c(NC(=O)c3ccc(N4CCN(C)CC4)cc3NCc3ccnn3C)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cc1c(CNC2CC(C)(C)C2)ccc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cc1ccncc1-c1cc2c(C(=O)Nc3ccc(N4CCN(C)CC4)cc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018152220A1_Original_document_20201120090908,Over 100 nM
Cc1nc2c(N3CC[C@@H](N)C3)c(NC(=O)c3ccnc(-c4c(F)cccc4F)n3)ccc2s1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(cnn3C)c2N(C)[C@H]2CCN(S(C)(=O)=O)C2)n1,HPK1,medium,100,Ki,US2019256500A1_Original_document_20201126122546,Over 100 nM
COc1cccc(C(=O)Nc2n[nH]c3cnc(-c4c(F)cccc4OC)cc23)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3cccc(N4CCN(S(C)(=O)=O)CC4)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cnc(-c5c(F)cccc5F)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cc1cc(NC(=O)CN2C[C@H]3CC[C@@H]2C3)cc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cnc(-c5cccc(F)c5F)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(cnn3C)c2N(C)[C@H]2CCN(C(C)=O)C2)n1,HPK1,medium,100,Ki,US2019256500A1_Original_document_20201126122546,Over 100 nM
CN(C)c1ccc(F)c(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c1F,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3ccc4c(c3)OCO4)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3ccncc3C#N)cc2N2C[C@H](O)C[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CCN1CCN(c2ccc(C(=O)Nc3n[nH]c4cnc(-c5c(F)cccc5OC)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)ccc2N2CCC[C@H]2CN)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3nn(C)cc3c2N(C)CCO)n1,HPK1,medium,100,Ki,US2019256500A1_Original_document_20201126122546,Over 100 nM
CNCc1cc(F)c(-c2cc3c(-c4cncc(N5CCN(C)CC5)c4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3ccc(N4CCN(C(C)C)CC4)cc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(nc(C)n3CC(C)(C)OC)c2N2CCC[C@H]2CN)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3c(F)cccc3C#N)cc2N2C[C@H](N)C[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(C)ccc2N2C[C@H](N)C[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(F)cc2N2C[C@H](N)C[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1cc2c(-c3cc(C)no3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(C5CCOCC5)cc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3cccc(N4CCN(CC(F)(F)F)C(=O)C4)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cnc(-c5c(F)cccc5C(F)(F)F)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cn1cc(-c2n[nH]c3cnc(-c4c(F)cc(OC5CCOCC5)cc4F)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cc1cc(CN2CCC2)cc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1cc2c(N3CCc4ccc(C#N)cc4C3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COC1CCCN(Cc2ccc(F)c(-c3cc4c(-c5cnn(C)c5)n[nH]c4cn3)c2F)C1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CCN1CCN(c2ccc(-c3n[nH]c4cc(C#N)c(-c5c(C)cc(CNC)cc5F)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
COc1cc(NC(=O)CN2CC(C)(C)C2)cc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1c(-c2cc3c(-c4ccc(N5CCN(C)CC5)cc4)n[nH]c3cn2)c(F)cc2c1C(N)CC2,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3cccc(N4CCN(C)CC4)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cn1c(-c2ccncc2F)nc2c(N3CCNC[C@@H]3CO)c(NC(=O)c3ccnc(-c4c(F)cccc4F)n3)ccc21,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3ccc(F)c(F)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3ccnc(N4CCN(C)CC4)c3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CNCc1cc(F)c(-c2cc3c(-c4cnn(-c5ccccc5C#N)c4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2cc(-c3n[nH]c4cnc(-c5c(F)cc6c(c5F)CNCC6)nc34)ccn2)CC1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3sc(C)nc3c2N(C)[C@@H]2CCCNC2)n1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
CC(=O)N1CCN(c2ccc(-c3n[nH]c4cnc(-c5c(F)cc6c(c5C)CNCC6)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CNCc1ccc(C)c(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cn1cc(-c2n[nH]c3cnc(-c4c(F)ccc(NC(=O)Cc5ccccc5)c4F)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1ccncc1-c1ncc2[nH]nc(-c3ccc(N4CCN(C)CC4)cc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CCOc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2N2C[C@H](N)C[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
Cc1nc2c(N3CC[C@@H](N)C3)c(NC(=O)c3ccnc(-c4c(C)cccc4F)n3)ccc2s1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
Cc1cncc(-c2ncc3[nH]nc(-c4ccc(N5CCN(C)CC5)cc4)c3n2)c1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3cc(C)n[nH]3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
Cc1c2c(cc(F)c1-c1ncc3[nH]nc(-c4ccnc(N5CCN(C)CC5)c4)c3n1)CCNC2,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COCCc1nc2c(N3CCC[C@H]3CN)c(NC(=O)c3ccnc(-c4c(F)cccc4OC)n3)ccc2n1C,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
CC(C(=O)Nc1cc(F)c(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c(F)c1)N1CCCC1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(C(C)(C)C#N)cc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
Cc1cc(CN2CCC(O)C2)cc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cc1cc(NC(=O)CN2CCCC2)cc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CCNCc1ccc(F)c(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c1OC,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3cccc(N4CCOCC4)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(cnn3C)c2N(C)CC2(O)COC2)n1,HPK1,medium,500,Ki,US2019256500A1_Original_document_20201126122546,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cnc(-c5ccccc5F)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1cc2c(/C=C/c3ccc(Br)cc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cn1cc(-c2n[nH]c3cnc(-c4cccc(CNC5CCOCC5)c4C(F)(F)F)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cn1cc(-c2n[nH]c3cnc(-c4c(F)cc(CNc5ccn(C)n5)cc4F)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2N2C[C@H](N)C[C@@H]2C(C)(C)O)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3sc(C)nc3c2N2CCC3CCNCC32)n1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
Cn1cc(-c2n[nH]c3cnc(-c4c(F)ccc(CNC5CC5)c4F)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
O=S(=O)(c1ccc(-c2n[nH]c3cnc(-c4c(F)cc5c(c4F)CNCC5)nc23)cc1)N1CCC1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
Cc1c(CN2CCC2)ccc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(cnn3C)c2N(C)CC2CCCO2)n1,HPK1,medium,100,Ki,US2019256500A1_Original_document_20201126122546,Over 100 nM
Cc1nc2c(N3C[C@@H]4CC[C@H]3CN4)c(NC(=O)c3ccnc(-c4c(F)cccc4F)n3)ccc2s1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5cccc6c5CCC6NCCO)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3sc(C)nc3c2N2CCOC[C@@H]2CN)n1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
Cc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2N2C[C@H](N)C[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
N[C@@H]1C[C@H](CO)N(c2ccc(F)cc2NC(=O)c2ccnc(-c3c(F)cccc3F)n2)C1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5cnc6c(c5)ncn6C)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
COC1CCN(c2ccc(C(=O)Nc3n[nH]c4cnc(-c5cnccc5C)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018152220A1_Original_document_20201120090908,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2N2CCN3C(=O)OC[C@@H]3C2)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CC(C)NCc1cc(F)c(-c2cc3c(NC(=O)c4ccc(N5CCN(C)CC5)cc4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c(CN3CCOCC3)cc2N2C[C@H]3C[C@@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(cnn3C)c2N(C)[C@H]2CCNC2)n1,HPK1,medium,100,Ki,US2019256500A1_Original_document_20201126122546,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3c(C#N)cnn3C)cc2N2C[C@H](N)C[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1ccccc1-c1ncc2[nH]nc(-c3ccc(N4CCN(C)CC4)cc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5cncc6oc(C(C)(C)C)nc56)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
Cc1cc(NC(=O)CN2C3CCC2CC3)cc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COC1CCN(c2ccc(C(=O)Nc3n[nH]c4cnc(-c5cnn(C)c5C)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018152220A1_Original_document_20201120090908,Over 100 nM
COc1ccc(F)c(F)c1-c1nccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2N2C[C@H](N)C[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)ccc2N2CCN[C@@H](CO)C2)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
Cc1c(F)ccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2N2C[C@H](N)C[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(CC#N)cc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(cnn3C)c2N(C)CC(C)(C)O)n1,HPK1,medium,100,Ki,US2019256500A1_Original_document_20201126122546,Over 100 nM
Cc1cc(NC(=O)CN(C)C)cc(Cl)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2N2CCO[C@@H](CO)C2)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1cc2c(-n3cnc(C(=O)NC(C)C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cnc(-c5ccc6c(c5)C(=O)NC6)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CN1CCC(NC(=O)c2ccc(-c3n[nH]c4ccc(-c5ccccc5F)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2N2CCN(CCO)CC2)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cc(N2CCN(C)CC2)ccc1C(=O)Nc1n[nH]c2cnc(-c3c(F)cc(CNC(C)C)cc3F)cc12,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3c(C)nn(C)c3C)cc2N2C[C@H]3C[C@@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)ccc2N2C[C@@H]3C[C@H]2CN3CCO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(C(F)(F)F)cc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3cccc(N4CCN(C)C(=O)C4)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CCN1CCN(c2cccc(C(=O)Nc3n[nH]c4cnc(-c5c(F)cccc5OC)cc34)c2)CC1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(N5CCN(C(C)=O)CC5)nc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)ccc2N2CCC[C@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5ccc(=O)n(C)c5)nc34)cc2)CC1,HPK1,medium,500,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3sc(C)nc3c2N2C[C@@H](N)C[C@H]2CO)n1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccccc2C2CCC(N)C2)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3ccn(C)c(=O)c3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)ccc2N2CC[C@@H](N)C2)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COCCNC(=O)c1cc(F)c(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3cccnc3C)cc2N2C[C@H]3C[C@@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CNCc1cc(F)c(-c2ncc3[nH]nc(-c4ccc(C5CCOCC5)cc4)c3n2)c(F)c1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CCCNc1ccc(C(=O)Nc2n[nH]c3cnc(-c4cnn(C)c4C)cc23)cc1,HPK1,medium,100,Ki,WO2018152220A1_Original_document_20201120090908,Over 100 nM
N#Cc1ccncc1-c1ccc(NC(=O)c2ccnc(-c3c(F)cccc3Cl)n2)c(N2C[C@H](N)C[C@@H]2CO)c1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cc(C)cc(F)c1-c1nccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2N2C[C@H](N)C[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1ccncc1-c1cc2c(NC(=O)c3ccc(N4CCN(C)CC4)cc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018152220A1_Original_document_20201120090908,Over 100 nM
COc1c(F)ccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2N2C[C@H](N)C[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3c(C)nn(C)c3C)cc2[C@H]2CC[C@@H](N)CC2)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CNCc1cc(C)c(-c2nccc(C(=O)Nc3ccc4sc(C)nc4c3N3CC[C@@H](N)C3)n2)c(F)c1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2N2C[C@H](N)C[C@@H]2C2(O)CC2)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CNC1CCc2cc(F)c(-c3ncc4[nH]nc(-c5cnn(C)c5)c4c3OC)c(F)c2C1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COCc1nc2c(N3CCC[C@H]3CN)c(NC(=O)c3ccnc(-c4c(F)cccc4OC)n3)ccc2s1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(ncn3C)c2N2CCC[C@H]2CN)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(N5CCC(O)CC5)nc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccccc2[C@H]2CC[C@H](N)CC2)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CC(=O)N1CCC(n2cc(-c3n[nH]c4ccc(-c5ccccc5F)nc34)cn2)CC1,HPK1,not active,10000,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(N5CCOCC5)nc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
CCOC(=O)c1cccc(-c2ccc3[nH]nc(-c4ccc(N5CCN(C)CC5)cc4)c3n2)c1F,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
COc1c(-c2ncc3[nH]nc(-c4ccc(N5CCOCC5)nc4)c3n2)c(F)cc2c1C(N)CC2,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COCCc1nc2c(N3CCC[C@H]3CN)c(NC(=O)c3ccnc(-c4c(F)cccc4OC)n3)ccc2s1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3c(C#N)cnn3C)cc2[C@H]2CC[C@@H](N)CC2)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4cnn(C5CC5)c4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)c(C(C)C)cc2N2CCN[C@@H](CO)C2)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COCCNc1ccc(C(=O)Nc2n[nH]c3cnc(-c4cnn(C)c4C)cc23)cc1,HPK1,medium,100,Ki,WO2018152220A1_Original_document_20201120090908,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccccc2C2CCCC(N)C2)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccccc2[C@H]2CC[C@@H](N)CC2)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cnc(-c5ccc6cccnc6c5F)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2N2CCO[C@H](CN(C)C)C2)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COC1CCCN(c2ccc(C(=O)Nc3n[nH]c4cnc(-c5cnn(C)c5C)cc34)cc2)C1,HPK1,medium,100,Ki,WO2018152220A1_Original_document_20201120090908,Over 100 nM
Cn1cc(-c2n[nH]c3cnc(-c4cccc(CN5CCC5)c4C(F)(F)F)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)ccc2N2C[C@H](NC(C)C)C[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2N2[C@H](CO)[C@H]3C[C@@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(nc(-c4ccncc4F)n3C)c2N2C[C@@H]3C[C@H]2CN3)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3ccncc3C#N)cc2N2C[C@H](N)C[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(S(=O)(=O)C(C)C)cc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)ccc2N2C[C@H](O)C[C@H]2C)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
N#Cc1ccncc1-c1ccc(NC(=O)c2ccnc(-c3c(F)cccc3OC(F)F)n2)c(N2C[C@H](N)C[C@@H]2CO)c1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(C)cc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5cnc6nccnc6c5)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CNCc1cc(C)c(-c2nc3c(-c4cnn(C)c4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3ccc(F)cc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
Cc1c(-c2cc3c(NC(=O)c4ccc(N5CCOCC5)cc4)n[nH]c3cn2)cnn1C,HPK1,medium,100,Ki,WO2018152220A1_Original_document_20201120090908,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2N2CC[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1ccc(-c2cnn(C)c2)c(F)c1-c1nccc(C(=O)Nc2ccc3sc(C)nc3c2N2C[C@H](N)C[C@H]2CO)n1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
CNCc1cc(F)c(-c2ncc3[nH]nc(-c4ccc(NC5CCN(S(C)(=O)=O)CC5)cc4)c3n2)c(F)c1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CNC(=O)c1ccc(-c2n[nH]c3cnc(-c4c(F)cccc4OC)cc23)cc1C,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)ccc2N2CCC3CNCC32)n1,HPK1,medium,500,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CNCc1cc(F)c(-c2cc3c(-c4ccc(N5CCN(C(C)=O)CC5)cn4)n[nH]c3cn2)c(OC(F)F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNC1CCc2cc(F)c(-c3cc4c(-c5ccc(N6CCN(C)CC6)cc5)n[nH]c4cn3)c(F)c2C1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)cc(Br)c2N2C[C@@H]3C[C@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2[C@H]2CC[C@@H](N)CC2)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CNCc1cc(C)c(-c2nc3c(-c4ccc(N5CCN(C)CC5)nc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(cnn3C)c2N(C)Cc2cccnc2)n1,HPK1,medium,100,Ki,US2019256500A1_Original_document_20201126122546,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3[nH]ccc3c2N2C[C@@H]3C[C@H]2CN3)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3ccc(C#N)cc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COCC1CN(c2cc(-c3cnccc3C#N)ccc2NC(=O)c2ccnc(-c3c(F)cccc3OC)n2)C1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CCn1cc(-c2n[nH]c3cnc(-c4c(C)cc(CNC)cc4F)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2N2CCN(C)CC2)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CNCc1cc(F)c(C2=NC=C3NN=C(c4cccc(C#N)c4)C3N2)c(F)c1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
N#Cc1ccncc1-c1ccc(NC(=O)c2ccnc(-c3c(F)cccc3F)n2)c(N2C[C@H](N)C[C@@H]2CO)c1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(Br)c3sc(C)nc3c2N2CC[C@H](N)C2)n1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
COc1cccc(F)c1-c1cc2c(N3CCN(c4ccc(C#N)cc4)CC3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(ccn3CCN3CCOCC3)c2N2C[C@@H]3C[C@H]2CN3)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
CC(C)NC1CC(c2cc(F)c(-c3cc4c(-c5cnn(C)c5)n[nH]c4cn3)c(F)c2)C1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cc1cccc(F)c1-c1cc2c(NC(=O)c3ccc(N4CCN(C)CC4)cc3N)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1ccc(C#N)c(F)c1-c1nccc(C(=O)Nc2cc(F)ccc2N2C[C@H](N)C[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2N2CC[C@@H](N)C[C@H]2C)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
Cc1nc2c(N3CC[C@@H](N)C3)c(NC(=O)c3ccnc(-c4c(F)cccc4C(F)(F)F)n3)ccc2s1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(C5CC5)cc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
COc1ccc(-n2ccc3c(N4C[C@@H](N)C[C@H]4CO)c(NC(=O)c4ccnc(-c5c(F)cccc5OC)n4)ccc32)c(F)c1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3ccncc3C#N)c(F)c2N2C[C@H]3C[C@@H]2CN3)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
Cc1ccncc1-c1cc2c(NC(=O)c3ccc(N4CCOCC4)cc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018152220A1_Original_document_20201120090908,Over 100 nM
CCOC(=O)N1CCN(c2ccc(C(=O)Nc3n[nH]c4cnc(-c5cnccc5C)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018152220A1_Original_document_20201120090908,Over 100 nM
CNC(=O)c1ccc(-c2n[nH]c3cnc(-c4c(F)cccc4OC)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CCOC(=O)N1CCN(c2ccc(C(=O)Nc3n[nH]c4cnc(-c5cnn(C)c5C)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018152220A1_Original_document_20201120090908,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(cnn3C)c2N(C)Cc2ccccc2)n1,HPK1,medium,100,Ki,US2019256500A1_Original_document_20201126122546,Over 100 nM
CNC(=O)c1ccc(-c2n[nH]c3cnc(-c4c(F)cc5c(c4F)CCCC5NC)cc23)cc1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cc1ccncc1-c1cc(Cl)c2nnc(NC(=O)C3CC3)cc2c1,HPK1,not active,1000,Ki,WO2020069402A1_Original_document_20201120091428,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(Cl)c3sc(C)nc3c2N2CC[C@H](N)C2)n1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
CNC(=O)c1ccc(-c2n[nH]c3cnc(-c4c(F)cccc4OC)cc23)cc1F,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cnc(-c5cncc(C(=O)N6CCOCC6)c5)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CNCc1ccccc1-c1c(NC(=O)c2ccnc(-c3c(F)cccc3OC)n2)ccc2c1cnn2C,HPK1,medium,100,Ki,US2019256500A1_Original_document_20201126122546,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3sc(C)nc3c2N2C[C@H]3C[C@@H]2CN3C(=O)N2CCOCC2)n1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3c(C#N)cnn3C)cc2[C@H]2CC[C@H](N)CC2)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2N2CC[C@H]2CN(C)C)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(OC)cc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(ccn3C)c2N2C[C@@H]3C[C@H]2CN3)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)ccc2N2CCNC[C@@H]2C)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
Cn1cc(-c2n[nH]c3cnc(-c4c(F)cc(NC(=O)CN5CC6(CCOCC6)C5)cc4F)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2N2CCO[C@@H](CC#N)C2)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3sc(C)nc3c2N(C)CC2CCN(C)C2)n1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5ccccc5C#N)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(cnn3C)c2N(C)C2CCOCC2)n1,HPK1,medium,100,Ki,US2019256500A1_Original_document_20201126122546,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4cccc(N5CCC(O)CC5)n4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
CNCc1cc(F)c(-c2cc3c(-c4cnc(N5CCC(O)CC5)nc4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)ccc2N2C[C@H](N(C)C)C[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(C(=O)NC(C)C)cc4Cl)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
COC(=O)N1CCN(c2ccc(C(=O)Nc3n[nH]c4cnc(-c5c(F)cc(CNC(C)C)cc5F)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1c(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c(F)cc2c1C(N)CC2,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(F)c(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c(C(F)(F)F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(F)c(-c2ncc3[nH]nc(-c4ccc(N5CCN(CCO)CC5)cc4)c3n2)c(F)c1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cnc(-c5cc(F)cc(C6(CN)CC6)c5)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(NC(C)=O)nc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
COc1cc(-n2ccc3c(N4C[C@@H]5C[C@H]4CN5)c(NC(=O)c4ccnc(-c5c(F)cccc5OC)n4)ccc32)ccn1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(cnn3C)c2N(C)C2CCN(C)CC2)n1,HPK1,medium,100,Ki,US2019256500A1_Original_document_20201126122546,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(cnn3C)c2N(C)C2CC2)n1,HPK1,medium,100,Ki,US2019256500A1_Original_document_20201126122546,Over 100 nM
CNCc1cc(F)c(-c2cc3c(-c4ccc(N5CCN(C)CC5)cc4)n[nH]c3cn2)c(C(F)(F)F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1cc2c(N3CCN(c4ccc(Br)cc4)C(=O)C3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(F)c(-c2ncc3[nH]nc(-c4ccc(N5CCC(C)(O)CC5)nc4)c3n2)c(F)c1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3ccc(CN4CCN(C)CC4)cc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cc1C#N,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(cnn3C)c2N(C)[C@H]2CCN(C(=O)N(C)C)C2)n1,HPK1,medium,100,Ki,US2019256500A1_Original_document_20201126122546,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(C#N)c3sc(C)nc3c2N2CC[C@H](N)C2)n1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3sc(C)nc3c2N2CC(F)(F)C[C@H]2CO)n1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
CCN1CCN(c2ccc(-c3n[nH]c4cc(C#N)c(-c5c(F)ccc6c5CCNC6)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
Cc1cc(CNC2CC(O)C2)cc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(F)c(-c2ncc3[nH]nc(-c4ccc(N5CCO[C@H](COC)C5)nc4)c3n2)c(C(F)(F)F)c1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
Cn1cc(-c2n[nH]c3cnc(-c4c(F)cc(NC(=O)CN5CCC5)cc4OC(F)F)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1ccncc1-c1cc2c(C(=O)Nc3ccc(N4CCN(C)CC4)cc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018152220A1_Original_document_20201120090908,Over 100 nM
CNCc1cc(F)c(-c2ncc3[nH]nc(-c4ccc(N5CCN(C(C)=O)CC5)nc4)c3n2)c(C(F)(F)F)c1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(cnn3C)c2N(C)C)n1,HPK1,medium,100,Ki,US2019256500A1_Original_document_20201126122546,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(-c3cnccc3C#N)cc2[C@H]2CC[C@H](N)CC2)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccnc(C)c4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(F)ccc2N2CCCC2c2ccccn2)n1,HPK1,medium,500,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CNCc1cc(F)c(-c2cc3c(-c4ccc(N5CCC(F)C5)cn4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cnc(-c5c(F)cc(O)cc5F)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cc(=O)n(-c5ncccc5F)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049191A1_Original_document_20200804051932,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(C)nc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
Cn1cc(-c2n[nH]c3cc(C#N)c(-c4c(F)ccc5c4CCNC5)nc23)cn1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CNCc1cc(C)c(-c2ncc3[nH]nc(-c4cnn(-c5ccccc5C#N)c4)c3n2)c(F)c1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CNC1CCc2cc(F)c(-c3ncc4[nH]nc(-c5ccc(N6CCOCC6)nc5)c4n3)c(F)c2C1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1ccccc1-n1cc2c(-c3ccc(N4CCN(C)CC4)cc3)n[nH]c2cc1=O,HPK1,medium,100,Ki,WO2018049191A1_Original_document_20200804051932,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2cc(C)c3sc(C)nc3c2N2CC[C@H](N)C2)n1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
Cc1c(N)cccc1-c1ccc2[nH]nc(-c3ccc(N4CCN(C)CC4)cc3)c2n1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3sc(C)nc3c2N2C[C@H](N)C[C@H]2CO)n1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
CNCc1cc(F)c(-c2cc3c(NC(=O)c4cccc(N5CCN(C)CC5)c4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(ccn3Cc3cnc(C)s3)c2N2C[C@@H]3C[C@H]2CN3)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
CNc1ccc(F)c(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c1F,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cnc(-c5c(F)cccc5CO)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4cnc(N5CCN(C)CC5)nc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4cnc(C)o4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
Cc1cc(CNCCO)cc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5ccccc5C(F)(F)F)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3sc(C)nc3c2N2C[C@H]3C[C@@H]2CO3)n1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
COc1cccc(F)c1-n1cc2c(-c3ccc(N4CCN(C)CC4)cc3)n[nH]c2cc1=O,HPK1,medium,100,Ki,WO2018049191A1_Original_document_20200804051932,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3cccc(N4CCNCC4)c3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CCN1CCN(c2ccc(NC(=O)c3n[nH]c4cnc(-c5c(F)cccc5OC)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(S(C)(=O)=O)c(F)c4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
COC1CN(C(=O)c2cc(F)c(-c3cc4c(-c5cnn(C)c5)n[nH]c4cn3)c(F)c2)C1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CCNCc1cc(F)c(-c2ncc3[nH]nc(-c4cnn(C)c4)c3n2)c(OC)c1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COC1CN(Cc2cc(F)c(-c3cc4c(NC(=O)c5ccc(N6CCN(C)CC6)cc5)n[nH]c4cn3)c(F)c2)C1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cc1c2c(cc(F)c1-c1ncc3[nH]nc(-c4ccc(N5CCOCC5)nc4)c3n1)CCNC2,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COC(=O)N1CCN(c2ccc(C(=O)Nc3n[nH]c4cnc(-c5c(F)cc(CNC(C)C)cc5F)cc34)c(F)c2)CC1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(C(=O)N(C)C)cc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(nc(C4CCOCC4)n3C)c2N2CCC[C@H]2CN)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
CCc1nc2c(N3C[C@@H](N)C[C@H]3CO)c(NC(=O)c3ccnc(-c4c(F)cccc4OC)n3)ccc2s1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
CNCc1cc(F)c(-c2ncc3[nH]nc(-c4cnn(C)c4)c3n2)c(OC)c1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5cccc(C(N)=O)c5F)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(ccn3-c3cccc(F)c3C#N)c2N2C[C@@H](N)C[C@H]2CO)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
Cc1cc(CNCC#N)cc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4cnc(OC)nc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
CNCc1cc(F)c(-c2ncc3[nH]nc(-c4ccc(C5CCNCC5)cc4)c3n2)c(F)c1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4cnsc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3ccc(CC#N)cc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(nc(C)n3C)c2N2CCC[C@@H]2CO)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
CNCc1cc(C)c(-c2nc3c(-c4ccc(C(=O)NC)nc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(C(=O)NC)cc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
Fc1cc2c(c(F)c1-c1ncc3[nH]nc(-c4ccc(N5CCOCC5)nc4)c3n1)CNCC2,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3sc(CN(C)C)nc3c2N2C[C@H](N)C[C@H]2CO)n1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
CNCc1cc(F)c(-c2cc3c(NC(=O)c4cnn(C)c4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNC1CCCc2c1ccc(F)c2-c1cc2c(-c3ccc(N4CCN(C)CC4)nc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
N#Cc1ccncc1-c1ccc(NC(=O)c2ccnc(-c3c(F)cccc3C3CC3)n2)c(N2C[C@H](N)C[C@@H]2CO)c1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CNCc1cc(F)c(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cc(=O)n(-c5ccccc5F)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049191A1_Original_document_20200804051932,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(ccn3-c3ccnn3C)c2N2C[C@@H](N)C[C@H]2CO)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
CNCc1cc(F)c(-c2ncc3[nH]nc(-c4ccc(N5CCN(S(C)(=O)=O)CC5)nc4)c3n2)c(F)c1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(nc(-c4ccncc4F)n3C)c2N2CCOC[C@@H]2CN)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
COCCNC(=O)Nc1cc(F)c(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(nc(C)n3C)c2N2CCC[C@@H]2CN)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
Cc1cc(NC(=O)CC#N)cc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(N5CC[C@H](F)C5)nc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
Cc1ccccc1-n1cc2c(-c3ccc(N4CCN(C)CC4)cc3)n[nH]c2cc1=O,HPK1,medium,100,Ki,WO2018049191A1_Original_document_20200804051932,Over 100 nM
CNCc1cc(F)c(-c2ncc3[nH]nc(-c4cnn(C)c4)c3n2)c(F)c1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5cncc6ccccc56)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CC(=O)NCc1cc(C)c(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(ccn3C)c2N2C[C@@H](N)C[C@H]2CO)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(C5CCOCC5)nc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
CNCc1cc(F)c(-c2ncc3[nH]nc(-c4ccc(N5CCN(CCOC)CC5)cc4)c3n2)c(F)c1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3sc(C)nc3c2N2C[C@H](NS(C)(=O)=O)C[C@H]2CO)n1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
CNCc1cc(F)c(-c2cc3c(-c4ccc(OC)cc4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cn1cc(-c2n[nH]c3cnc(-c4c(F)cc5c(c4F)C(N)CC5)c(F)c23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cc1cc(C2CCCCN2)cc(F)c1-c1ncc2[nH]nc(-c3ccc(N4CCN(C)CC4)cc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(nc(-c4ncccc4F)n3C)c2N2C[C@H](N)C[C@H]2CO)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(CO)cc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
Cc1cccc(F)c1-c1ccc2[nH]nc(-c3ccc(N4CCN(C)CC4)cc3)c2n1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CNCc1cc(F)c(-c2ncc3[nH]nc(-c4ccc(N5CCN(CC(C)(C)O)CC5)nc4)c3n2)c(F)c1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CNCc1cc(F)c(-c2ncc3[nH]nc(-c4cnn(C)c4)c3c2OC)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COC[C@@H](C)n1c(C)nc2c(N3CCC[C@H]3CN)c(NC(=O)c3ccnc(-c4c(F)cccc4OC)n3)ccc21,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
CNCc1cc(C)c(-c2nc3c(-c4cnc(N5CCOCC5)nc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CCN1CCN(c2ccc(-c3n[nH]c4cc(C#N)c(-c5c(C)cccc5F)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CNC(=O)c1ccc(-c2n[nH]c3cnc(-c4c(F)cccc4OC)cc23)cc1OC,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CS(=O)(=O)NCc1ccc(-c2n[nH]c3cnc(-c4c(F)cc5c(c4F)CNCC5)nc23)cc1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CNC1CCc2cc(F)c(-c3cc4c(-c5ccc(N6CCN(C)CC6)cc5)n[nH]c4cn3)c(F)c21,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(C)c(-c2nc3c(-c4cccnc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CN1CCN(c2ccc(C(=O)Nc3n[nH]c4cnc(-c5c(F)cc(CN6CCCC6)cc5F)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cc(=O)n(-c5cccc6c5CCNC6)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049191A1_Original_document_20200804051932,Over 100 nM
CCn1cc(-c2n[nH]c3cc(C#N)c(-c4c(C)cc(CNC)cc4F)cc23)cn1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cnc(-c5c(F)ccc6c5CCCC6N)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cc1c2c(cc(F)c1-c1ncc3[nH]nc(-c4ccc(N5CCN(C)CC5)cc4)c3n1)CCNC2,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CCN(C)C(=O)N1CCN(c2ccc(-c3n[nH]c4cnc(-c5c(F)cc(CNC)cc5F)nc34)cn2)CC1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CNCc1cc(C)c(-c2nc3c(-c4ccc(C(C)(C)O)nc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CCN1CCN(c2ccc(-c3n[nH]c4cnc(-c5c(C)cc(C6CCCCN6)cc5F)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CCNCc1cc(F)c(-c2cc3c(NC(=O)c4ccc(N5CCN(C)CC5)cc4)n[nH]c3cn2)c(C(F)(F)F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1cc2c(C(=O)Nc3ccc(N4CCN(C)CC4)cc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3cccc(N(C)C)c3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5cccc(C(=O)NCc6ccccc6)c5F)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4cnn(C5CC5)c4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(C(=O)NC)cc4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cc(NC(=O)OC2CCN(C)CC2)cc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1ccc(F)c(F)c1-c1ccc2[nH]nc(-c3ccc(N4CCN(C)CC4)cc3)c2n1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
Fc1ccccc1-c1ccc2[nH]nc(-c3ccccc3)c2n1,HPK1,medium,500,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CNC1(c2cc(F)c(-c3cc4c(-c5cnn(C)c5)n[nH]c4cn3)c(F)c2)CC1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CC(c1ccccc1C(F)(F)F)n1cc2c(-c3ccc(N4CCN(C)CC4)cc3)n[nH]c2cc1=O,HPK1,medium,100,Ki,WO2018049191A1_Original_document_20200804051932,Over 100 nM
Cn1cc(-c2n[nH]c3cnc(-c4c(F)ccc5c4CCCC5N)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cn1cc(-c2n[nH]c3cnc(-c4c(F)cc5c(c4F)C(O)CC5)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cc1n[nH]cc1-c1ccc2[nH]nc(-c3ccc(N4CCN(C)CC4)cc3)c2n1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cnc(-c5c(F)cc6c(c5F)CNCC6)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CNCc1cc(F)c(-c2ncc3[nH]nc(-c4ccc(C(=O)NC)nc4)c3n2)c(F)c1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cnc(-c5c(F)cccc5Cl)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1ccc(F)c(F)c1-c1ncc2[nH]nc(-c3ccc(N4CCN(C)CC4)cc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3ccnc(N4CCNCC4)c3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CNC1CCCc2c1cc(F)c(-c1cc3c(-c4cnn(C)c4)n[nH]c3cn1)c2F,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CCNCc1cccc(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c1C(F)(F)F,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1ccc(F)c(F)c1-c1nccc(C(=O)Nc2ccc3sc(C)nc3c2N2C[C@H](N)C[C@H]2CO)n1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
COc1cccc(F)c1-c1nc(C(=O)Nc2ccc3c(nc(C)n3C)c2N2CCC[C@H]2CN)ccc1F,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cnc(-c5c(F)cccc5CN)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cc1c2c(cc(F)c1-c1ncc3[nH]nc(-c4ccc(N5CCN(C)CC5)nc4)c3n1)CCNC2,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
OCCNc1ncc(-c2n[nH]c3cnc(-c4c(F)cc5c(c4F)CNCC5)nc23)cn1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(C5(C#N)CC5)cc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cnc(-c5cccnc5)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
Cc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(nc(C)n3C)c2N2CCC[C@H]2CN)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
COc1cccc(C(=O)Nc2n[nH]c3cnc(-c4c(F)cc(CNC(C)C)cc4F)cc23)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1cc2c(-c3cnc(C)s3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNC(=O)c1ccc(-c2n[nH]c3cnc(-c4c(C)cc(C5CCCN5)cc4F)cc23)cc1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cc1cc(CNCC(C)(C)O)cc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(F)c(-c2ncc3[nH]nc(-c4ccc(C(=O)NC)c(F)c4)c3n2)c(F)c1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
Cc1cc(C2CCCN2)cc(F)c1-c1ncc2[nH]nc(-c3ccc(N4CCN(C)CC4)cc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
COC(=O)c1ccccc1-c1ccc2[nH]nc(-c3ccc(N4CCN(C)CC4)cc3)c2n1,HPK1,medium,500,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
COc1ccc(F)c(F)c1-c1nccc(C(=O)Nc2cc(F)ccc2N2C[C@H](N)C[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4cnco4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
CC(C)NCc1cc(F)c(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4cnn(CC(F)(F)F)c4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
CNc1ncc(-c2n[nH]c3cnc(-c4c(F)cc5c(c4F)CNCC5)nc23)cn1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4cccc(N5CCN(C)CC5)n4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
CNCc1ccc(F)c(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c1OC,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc(C(C)C)cc2N2C[C@H](N)C[C@@H]2CO)n1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CNCc1cccc(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c1C(F)(F)F,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4cnn(-c5ccccc5C#N)c4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3ccc(N4CCN(CC(F)(F)F)C(=O)C4)cc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3ccccc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(N5CCCC(OC)C5)nc4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1cc2c(C(=O)Nc3ccc(N4CCOCC4)cc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cc(=O)n(C5CCN(C)C5=O)cc34)cc2)CC1,HPK1,medium,500,Ki,WO2018049191A1_Original_document_20200804051932,Over 100 nM
CNCc1cc(F)c(-c2ncc3[nH]nc(-c4ccc(OC)cc4)c3n2)c(F)c1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CNC(=O)c1ccc(-c2n[nH]c3cnc(-c4c(F)cc5c(c4F)C(NC)CC5)cc23)cc1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cn1cc(-c2n[nH]c3cc(C#N)c(-c4ccccc4F)cc23)cn1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
COc1cccc(F)c1-c1cc2c(N3CCN(c4ccncc4)CC3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cc1cccc(F)c1-c1cc2c(NC(=O)c3ccc(N4CCN(C)CC4)cc3NCC(C)O)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNC1CCc2c1cc(F)c(-c1cc3c(-c4cnn(C)c4)n[nH]c3cn1)c2F,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ccc(C(=O)Nc3n[nH]c4cnc(-c5c(F)cc(CN6CCC6)cc5F)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(-c2n[nH]c3cnc(-c4c(F)cccc4OC)nc23)c1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CNCc1cc(F)c(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c(C(F)F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(S(C)(=O)=O)cc4Cl)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
CNC(=O)c1ccc(-c2n[nH]c3cnc(-c4c(F)cccc4OC)nc23)cc1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4cnn(-c5ccccc5Cl)c4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
Cc1cccc(F)c1-c1cc2c(-c3ccc(N4CCN(C)CC4)cc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3ccc(N4CCOCC4)cc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cc(C#N)c(-c5c(F)ccc6c5CCNC6)nc34)cn2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
Cc1cccc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cc1C#N,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
CNCc1ccc(F)c(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c1C,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5cnc6c(c5)CC(=O)N6)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3c(nc(C)n3C)c2-c2ccccc2N)n1,HPK1,medium,100,Ki,US2019315717A1_Original_document_20201120073543,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3ccc(C(C)(C)C#N)cc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
Cn1cc(-c2n[nH]c3cnc(-c4c(F)ccc(CCNC5CCOCC5)c4F)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cc1cccc(F)c1-c1nc2c(-c3ccc(N4CCN(C)CC4)nc3)n[nH]c2cc1C#N,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
Cc1cccc(F)c1-c1ncc2[nH]nc(-c3ccc(N4CCCC(O)C4)cc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
Cc1ccccc1-c1cc2c(-c3cnn(C)c3)n[nH]c2cc1C#N,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
COc1cccc(F)c1-c1cc2c(NC(=O)c3ccc(N4CCNCC4)cc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cc1cc(NC(=O)CN(C)C)cc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Cc1cc(C2COCCN2)cc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(F)c(-c2cc3c(-c4cnn(C5CNC5)c4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(C)c(-c2ncc3[nH]nc(-c4cnn(C)c4)c3n2)c(F)c1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4ccc(C(=O)NC)c(F)c4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
Cc1cc(NC(=O)CCN(C)C)cc(F)c1-c1cc2c(-c3cnn(C)c3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNC1CCCc2c1ccc(F)c2-c1cc2c(-c3ccc(N4CCN(C)CC4)cc3)n[nH]c2cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1nccc(C(=O)Nc2ccc3sc(C)nc3c2N2C[C@H](NC(C)C)C[C@H]2CO)n1,HPK1,medium,100,Ki,US2020048241A1_Original_document_20200804052025,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4cn[nH]c4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
CNCc1cc(F)c(-c2cc3c(-c4ccc(C5CC5)nc4)n[nH]c3cn2)c(C(F)(F)F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CN(C)c1cc(F)c(-c2cc3c(-c4cnn(C)c4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cnccc1-c1ccc(NC(=O)c2ccnc(-c3c(F)cccc3OC)n2)c(N2C[C@H](N)C[C@@H]2CO)c1,HPK1,medium,100,Ki,WO2019164846A1_Original_document_20201126121419,Over 100 nM
CNC1CCc2c1cc(F)c(-c1cc3c(-c4ccc(N5CCN(C)CC5)cc4)n[nH]c3cn1)c2F,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
COc1cccc(F)c1-c1ncc2[nH]nc(-c3ccncc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4cnc(-c5c(F)cccc5CC#N)cc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(F)c(-c2cc3c(-c4cnn(CCO)c4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CNCc1cc(C)c(-c2nc3c(-c4cnc(N5CCN(C)CC5)nc4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CNCc1cc(F)c(-c2cc3c(-c4cnc(N5CCN(C)CC5)nc4)n[nH]c3cn2)c(F)c1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
CC[C@@H](C)Nc1ccc(-c2n[nH]c3cc(C#N)c(-c4c(C)cc(CNC)cc4F)cc23)cn1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
Cc1cccc(F)c1-c1ncc2[nH]nc(-c3ccc(N4CCC(O)C4)cc3)c2n1,HPK1,medium,100,Ki,WO2018049152A1_Original_document_20201230133552,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5c(F)cccc5CO)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
COc1cccc(F)c1-c1ccc2[nH]nc(-c3ccc(N4CCN(C)CC4)cc3)c2n1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CN1CCN(c2ccc(-c3n[nH]c4ccc(-c5cccc6c5CCNC6)nc34)cc2)CC1,HPK1,medium,100,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CNCc1cc(C)c(-c2cc3c(-c4cccc(N5CC[C@H](N(C)C)C5)n4)n[nH]c3cc2C#N)c(F)c1,HPK1,medium,100,Ki,WO2019051199A1_Original_document_20201120074819,Over 100 nM
CCn1cc(-c2n[nH]c3cnc(-c4c(C)cc(C5CCCCN5)cc4F)cc23)cn1,HPK1,medium,100,Ki,WO2018049200A1_Original_document_20201120080113,Over 100 nM
Fc1ccccc1-c1ccc2[nH]nc(-c3ccncc3)c2n1,HPK1,medium,500,Ki,WO2018049214A9_Original_document_20201120081540,Over 100 nM
CC[C@@H]1[C@@H](C(=O)Nc2cc3cc(-c4cncc(N)c4C)c(F)c(N)c3cn2)[C@@H]1c1cncn1C,HPK1,active,0.33,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(NC[C@H]3C[C@@H]3c3ccn[nH]3)ncc2c(N)c1F,HPK1,active,0.13,Ki,WO2018183964A1(1),Below 1 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@@H](C#N)[C@H]3C)ncc2c(N)c1F,HPK1,active,0.55,Ki,WO2018183964A1(1),Below 1 nM
Cc1c(N)cncc1-c1cc2cc(Nc3cc4n(n3)CS(=O)(=O)N(C(C)C)C4)ncc2c(N)c1F,HPK1,active,0.51,Ki,WO2018183964A1(1),Below 1 nM
CCc1nnc(-c2cccc(N3Cc4c(cc(N5CCC[C@H]5C)nc4CNC)C3=O)n2)n1CC(C)C,HPK1,active,0.22,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CCNc1cc2c(c(CNC)n1)CN(c1cccc(-c3nncn3CC)n1)C2=O,HPK1,active,0.64,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(N4CCC4)nc3CNC)C2=O)n1,HPK1,active,0.42,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCCn1c(C)nnc1-c1cccc(N2Cc3c(cc(C4(C)CC4)nc3CN)C2=O)n1,HPK1,active,0.63,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
CCC(CC)n1c(C)nnc1-c1cccc(N2Cc3c(cc(N4CCC[C@@H]4C)nc3CNC)C2=O)n1,HPK1,active,0.8,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CCN(c1cc2c(c(CNC)n1)CN(c1cccc(N3C(=O)OC[C@@H]3CF)n1)C2=O)C(C)C,HPK1,active,0.96,Ki,AU2019378184A1（HPK1）Ki,Below 1 nM
CCC(CC)n1cnnc1-c1cccc(N2Cc3c(cc(N4CCC[C@@H]4C)nc3CNC)C2=O)n1,HPK1,active,0.05,Ki,WO2020100027A1_Original_document_20201118034955,Below 1 nM
NCc1nc(C2CC2)cc2c1CN(c1cccc(N3C(=O)OC[C@@H]3CF)n1)C2=O,HPK1,active,3.04,Ki,AU2019378184A1（HPK1）Ki,1 nM to 10 nM
N#C[C@H]1C[C@@H]1C(=O)Nc1cc2cc(-c3cn[nH]c3)cc(N)c2cn1,HPK1,active,5.5,Ki,WO2018183964A1(1),1 nM to 10 nM
CCN(CC)c1cc2c(c(CN(C)C)n1)CN(c1cccc(-c3nncn3CC)n1)C2=O,HPK1,active,2.52,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC[C@@H]3C[C@H]3c3ccn[nH]3)ncc2c(N)c1F,HPK1,active,5.9,Ki,WO2018183964A1(1),1 nM to 10 nM
CNCc1nc(C(C)C)cc2c1CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,2.1,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C3=CN(C)NN3)ncc2c(N)c1F,HPK1,active,1.3,Ki,WO2018183964A1(1),1 nM to 10 nM
C[C@H]1COC(=O)N1c1cccc(N2Cc3c(cc(N4[C@H](C)C[C@H]4C)nc3CN)C2=O)n1,HPK1,active,1.92,Ki,AU2019378184A1（HPK1）Ki,1 nM to 10 nM
CCCn1cnnc1-c1cccc(N2Cc3c(cc(C4(C)CC4)nc3CN)C2=O)n1,HPK1,active,1.46,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
Cc1ccncc1-c1cc(N)c2nnc(NC(=O)C3CC3)cc2c1,HPK1,active,1.9,Ki,WO2021004535A1,1 nM to 10 nM
CNCc1nc(C2(C)CC2)cc2c1CN(c1cccc(N3C(=O)OC[C@@H]3C)n1)C2=O,HPK1,active,1.46,Ki,AU2019378184A1（HPK1）Ki,1 nM to 10 nM
CNCc1nc(C)cc2c1CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,7.1,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
C[C@H]1COC(=O)N1c1cccc(N2Cc3c(cc(C(C)(C)C)nc3CN)C2=O)n1,HPK1,active,5.1,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
CNCc1nc(C2(C)CC2)cc2c1CN(c1cccc(-c3nncn3C(C)C)n1)C2=O,HPK1,active,1.46,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
CCN(c1cc2c(c(CNC)n1)CN(c1cccc(-c3nncn3C)n1)C2=O)C(C)C,HPK1,active,3.7,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
CC[C@@H]1[C@@H](C(=O)Nc2cc3cc(-c4cncc(N)c4C)c(F)c(N)c3cn2)[C@@H]1c1cnn(C)c1,HPK1,active,8.5,Ki,WO2018183964A1(1),1 nM to 10 nM
CNCc1nc(C(C)(C)C)cc2c1CN(c1cccc(N3C(=O)OC[C@@H]3C)n1)C2=O,HPK1,active,1.8,Ki,WO2020100027A1_Original_document_20201118034955,1 nM to 10 nM
CC[C@H](CC(F)(F)F)n1cnnc1-c1cccc(N2Cc3c(cc(C(C)(C)C)nc3CNC)C2=O)n1,HPK1,active,7.1,Ki,AU2019378184A1（HPK1）Ki,1 nM to 10 nM
CNCc1nc(C2(C)CC2)cc2c1CN(c1ccc(F)c(-c3nncn3C(C)C)n1)C2=O,HPK1,active,35.2,Ki,WO2020100027A1_Original_document_20201118034955,10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3C[C@@H]3CO)ncc2c(N)c1F,HPK1,active,70,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@H]3CO)ncc2c(N)c1F,HPK1,active,70,Ki,WO2018183964A1(1),10 nM to 100 nM
Cc1ccncc1-c1cc2cc(NC(=O)[C@@H]3[C@@H](CC#N)[C@@H]3CN(C)C)ncc2c(N)c1F,HPK1,active,82,Ki,WO2018183964A1(1),10 nM to 100 nM
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3c(C)cccc3Cl)cc12,3CL,active,9,Ki,WO2021205290A1,1 nM to 10 nM
CC(C)C[C@H](NC(=O)c1cc2ccccc2[nH]1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)CO,3CL,active,38,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)CO)cc12,3CL,active,83,ic50,WO2021151265A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3c(C)ccnc3CN(C)C)cc12,3CL,active,14,Ki,WO2021205290A1,10 nM to 100 nM
COc1ccc(OCC(=O)N2CC3C([C@H]2C(=O)N[C@H](C=O)C[C@@H]2CCNC2=O)C3(C)C)cc1OC,3CL,active,14.5,ic50,CN113321650A, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)C2CN(C(=O)Oc3ccc(OC(F)(F)F)cc3)[C@H](C(=O)N[C@H](C=O)C[C@@H]3CCNC3=O)C21,3CL,active,15.2,ic50,CN113321650A, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)[C@@H]3CCCN3C)cc12,3CL,active,2,Ki,WO2021205290A1,1 nM to 10 nM
COc1ccc(C)c2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C#N)C[C@@H]3CCNC3=O)cc12,3CL,active,29,Ki,WO2021205290A1,10 nM to 100 nM
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3ccccc3Cl)cc12,3CL,active,11,Ki,WO2021205290A1,10 nM to 100 nM
O=C(Oc1cncc(Br)c1)c1ccco1,3CL,active,50,ic50,WO2021205290A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@H](C=O)CC1CCNC1=O,3CL,active,42,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)C2CN(C(=O)COc3cc(F)cc(F)c3)[C@H](C(=O)N[C@H](C=O)C[C@@H]3CCNC3=O)C21,3CL,active,18.5,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(OC(C)(C)C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC1CCCCC1)C(=O)N[C@H](C=O)C[C@@H]1CCNC1=O,3CL,active,53,Ki,WO2021188620A1,10 nM to 100 nM
O=C(/C=C/c1ccccc1)N[C@@H](CC1CCCCC1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)C(=O)NCc1ccccc1,3CL,active,0.4,ec50,WO2021160220A1, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)N[C@H](C(=O)N1C[C@H](C(F)(F)F)C[C@H]1C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O)C(C)(C)C,3CL,active,3,Ki,WO2018042343A2,1 nM to 10 nM
O=C(N[C@H]1CCOC1)[C@H](c1cnccn1)N(C(=O)CCl)c1ccc(-c2ccno2)cc1,3CL,active,71,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)[C@H]2CN(C(=O)[C@H](Cc3ccccn3)NC(=O)C(F)(F)F)[C@H](C(=O)N[C@H](C#N)C[C@@H]3CCNC3=O)[C@H]21,3CL,active,15,Ki,WO2021212039A1,10 nM to 100 nM
O=C(N[C@H]1CCC(F)(F)C1)[C@@H](c1cncnc1)N(C(=O)CCl)c1ccc(-c2cncs2)cc1,3CL,active,60,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc2c(c1)OCO2,3CL,active,78,ic50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
COc1c(F)ccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C#N)C[C@@H]3CCNC3=O)cc12,3CL,active,18,Ki,CN113197895A,10 nM to 100 nM
CC(C)C[C@H](NC(=O)[C@@H](NC(=O)COc1ccc(O)cc1)C(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)c1nc2ccccc2s1,3CL,active,11,Ki,CN113181339A,10 nM to 100 nM
Nc1ccccc1C(=O)On1nnc2ccccc21,3CL,active,19.5,Ki,WO2005113580A1,10 nM to 100 nM
CC1(C)[C@H]2CN(C(=O)[C@H](CC3CCC3)NC(=O)C(F)(F)F)[C@H](C(=O)N[C@H](C#N)C[C@@H]3CCNC3=O)[C@H]21,3CL,active,6,Ki,WO2021212039A1,1 nM to 10 nM
COc1ccc(F)c2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C#N)C[C@@H]3CCNC3=O)cc12,3CL,active,2,Ki,WO2021212039A1,1 nM to 10 nM
CC1(C)C2CN(C(=O)COc3ccc(Br)c(Cl)c3)[C@H](C(=O)N[C@H](C=O)C[C@@H]3CCNC3=O)C21,3CL,active,50.8,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)C3CCN(C)CC3)cc12,3CL,active,6,Ki,WO2021205290A1,1 nM to 10 nM
CC(C)C[C@H](NC(=O)c1cc2c(Cl)cc(Cl)cc2[nH]1)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,active,41,Ki,WO2005113580A1,10 nM to 100 nM
CC(C)C[C@H](NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(=O)N[C@H](C=O)C[C@@H]1CCNC1=O,3CL,active,8.5,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C#N)C[C@@H]3CCNC3=O)cc12,3CL,active,26,Ki,CN113181339A,10 nM to 100 nM
CC(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CC1CCCCC1)C(=O)N[C@H](C=O)Cc1c[nH]cn1)C(C)C,3CL,active,65,ic50,CN113321650A, not Ki or Kd; not used in NCI fingerprint analysis
O=c1c2ccccc2[se]n1Cc1ccco1,3CL,active,31,Ki,WO2021188620A1,10 nM to 100 nM
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3ccccc3C)cc12,3CL,active,71,Ki,WO2021205290A1,10 nM to 100 nM
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3ccccc3CN(C)C)cc12,3CL,active,14,Ki,WO2021205290A1,10 nM to 100 nM
CC(C)C[C@H](NC(=O)c1cc2c(O)cccc2[nH]1)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,active,68,Ki,WO2021205290A1,10 nM to 100 nM
CC(C)C[C@H](NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)OC(C)(C)C)C(=O)N[C@H](/C=C/C(=O)OC1CC1)C[C@@H]1CCNC1=O,3CL,active,99,Ki,WO2021212039A1,10 nM to 100 nM
Cn1ccc(CN(C(=O)Cn2nnc3ccccc32)c2ccc(-c3ccccc3)cc2)c1,3CL,active,51,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)[C@H]2CN(C(=O)[C@@H](CC3CCC3)NC(=O)C(F)(F)F)[C@H](C(=O)N[C@H](C#N)C[C@@H]3CCNC3=O)[C@H]21,3CL,active,7,Ki,WO2021212039A1,1 nM to 10 nM
CCOC(=O)/C=C/[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)OC(C)(C)C,3CL,active,50,Ki,WO2021212039A1,10 nM to 100 nM
CC(C)[C@H](NC(=O)[C@H](C)NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)[C@@H](O)[C@H](O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)OCc1ccccc1)C(C)C,3CL,active,73,Ki,WO2021219089A1,10 nM to 100 nM
O=C(Oc1cncc(Cl)c1)c1ccco1,3CL,active,60,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)C(=O)NC1CC1,3CL,active,13,Ki,CN113321650A,10 nM to 100 nM
CCCC[C@H](NC(=O)c1cc2c(OC)cccc2[nH]1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)CO,3CL,active,10,Ki,WO2021219089A1,10 nM to 100 nM
CC(C)C[C@H](NC(=O)OCC1CCC(F)(F)CC1)C(=O)N[C@H](C=O)C[C@@H]1CCNC1=O,3CL,active,7,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)C[C@H](NC(=O)C1CCCO1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)CO,3CL,active,91,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3ccc(C#N)cc3)cc12,3CL,active,2,Ki,WO2021188620A1,1 nM to 10 nM
O=C[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@@H]1C2CCCC2CN1C(=O)CCc1cc(F)cc(F)c1,3CL,active,7.6,ic50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)C[C@H](NC(=O)[C@H]1CCCO1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)COC(=O)c1c(Cl)cccc1Cl,3CL,active,3,Ki,WO2021212039A1,1 nM to 10 nM
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(C)=O)cc12,3CL,active,19,Ki,WO2021212039A1,10 nM to 100 nM
CC(C)[C@H](NC(=O)C(F)(F)F)C(=O)N1C[C@H]2[C@@H]([C@H]1C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)c1nc3ccccc3s1)C2(C)C,3CL,active,12,Ki,WO2021212039A1,10 nM to 100 nM
O=C(NC1CCC(F)(F)CC1)C(c1cnccn1)N(C(=O)CCl)c1ccc(-c2cncs2)cc1,3CL,active,80,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CC1CCCCC1)C(=O)NC(C=O)Cc1c[nH]cn1)C(C)C)C(C)O,3CL,active,98,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(C(=O)OCC(=O)[C@H](C[C@@H]2CCNC2=O)NC(=O)[C@H](CC(C)C)NC(=O)c2cc3c(OC)cccc3[nH]2)cc1,3CL,active,33,Ki,WO2021219089A1,10 nM to 100 nM
O=C(On1nnc2ccccc21)c1ccc2[nH]ccc2c1,3CL,active,7.5,Ki,WO2021219089A1,1 nM to 10 nM
CC(C)(C)[C@H](NC(=O)C(F)(F)F)C(=O)N1C[C@H]2[C@@H]([C@H]1C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O)C2(C)C,3CL,active,3,Ki,CN105837487A,1 nM to 10 nM
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3c(C)ccnc3C)cc12,3CL,active,4,Ki,WO2021205290A1,1 nM to 10 nM
CC(C)[C@H](NC(=O)c1ccc2ccccc2n1)C(=O)N[C@@H](CC1CCCCC1)C(=O)N[C@H](C=O)C[C@@H]1CCNC1=O,3CL,active,74,ic50,CN113181339A, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(OCC(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]2CCNC2=O)C(=O)c2nc3ccccc3s2)C(C)C)cc1,3CL,active,14,Ki,WO2021219089A1,10 nM to 100 nM
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3c(C)cc(F)cc3C)cc12,3CL,active,44,Ki,WO2021205290A1,10 nM to 100 nM
CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC1CCNC1=O)C(O)S(=O)(=O)O,3CL,active,30,ic50,WO2021205290A1, not Ki or Kd; not used in NCI fingerprint analysis
COCC(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC(C)C)NC(=O)c1cc2c(OC)cccc2[nH]1,3CL,active,51,ic50,US20150133368A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)c1cc2cc(Cl)ccc2[nH]1)C(=O)C[C@@H](C[C@@H]1CCNC1=O)C(=O)c1nc2ccccc2s1,3CL,active,28,Ki,WO2021205290A1,10 nM to 100 nM
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)CO)cc12,3CL,active,0,Ki,WO2021219089A1,Below 1 nM
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3ccccc3)cc12,3CL,active,74,Ki,WO2021205290A1,10 nM to 100 nM
O=C(NCc1ccccc1)C(=O)[C@H](C[C@@H]1CCCNC1=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)c1cnc2ccccc2n1,3CL,active,0.2,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NCc1ccccc1)C(=O)[C@H](C[C@@H]1CCCNC1=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)c1cc2ccccc2[nH]1,3CL,active,0.1,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)CO)cc12,3CL,active,7,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)C[C@@H](C[C@@H]3CCNC3=O)C(=O)c3nc4ccccc4s3)cc12,3CL,active,6.3,Ki,CN113197895A,1 nM to 10 nM
CNc1ccc(C(=O)On2nnc3ccccc32)cc1,3CL,active,12.1,Ki,CN113197895A,10 nM to 100 nM
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COP(=O)(O)O)cc12,3CL,active,58,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3ccc(Cl)cc3)cc12,3CL,active,19,Ki,WO2021188620A1,10 nM to 100 nM
CC1(C)C2CN(C(=O)COc3ccc(Cl)cc3)[C@H](C(=O)N[C@H](C=O)C[C@@H]3CCNC3=O)C21,3CL,active,19,ic50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)[C@H](NS(C)(=O)=O)C(=O)N1C[C@H]2[C@@H]([C@H]1C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)c1nc3ccccc3s1)C2(C)C,3CL,active,8,Ki,WO2021219089A1,1 nM to 10 nM
CC(C)C[C@H](NC(=O)[C@H](CN(C)C)NC(=O)OCc1ccccc1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)C(=O)NC(C)(C)C,3CL,active,7,ic50,WO2013049382A3, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)[C@@H](NC(=O)COc1ccccc1)C(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)c1nc2ccccc2s1,3CL,active,22,Ki,WO2021212039A1,10 nM to 100 nM
CC(C)C[C@@H](NC(=O)[C@H](NC(=O)OCc1ccccc1)C(C)C)C(=O)N[C@H](C[C@H]1CCNC1=O)C(=O)c1nc2ccccc2s1,3CL,active,4.1,Ki,WO2018042343A2,1 nM to 10 nM
CC(=O)/C=C/[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CNC(=O)C(C)(C)C)NC(=O)OCc1ccccc1,3CL,active,38,Ki,WO2021212039A1,10 nM to 100 nM
O=C(NC1CCC(F)(F)CC1)C(c1cnccn1)N(C(=O)CCl)c1ccc(-c2ccns2)cc1,3CL,active,62,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)[C@H](NC(=O)C(F)(F)F)C(=O)N1C[C@H](C(F)(F)F)C[C@H]1C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,active,37,Ki,WO2021212039A1,10 nM to 100 nM
O=C(Oc1cncc(Cl)c1)c1ccc(-c2ccc([N+](=O)[O-])cc2)o1,3CL,active,60,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3c(C)nc(C)nc3C)cc12,3CL,active,6,Ki,WO2021205290A1,1 nM to 10 nM
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3ccc(C)cc3C#N)cc12,3CL,active,17,ic50,WO2021151265A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)OC(C)(C)C)C(=O)N[C@H](/C=C/C(=O)C1CC1)C[C@@H]1CCNC1=O,3CL,active,99,Ki,CN113321650A,10 nM to 100 nM
CC(C)[C@H](NC(=O)c1cc2ccccc2[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C=O)C[C@@H]1CCNC1=O,3CL,active,50,ic50,WO2021205298A1, not Ki or Kd; not used in NCI fingerprint analysis
CCC(=O)OCC(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC(C)C)NC(=O)c1cc2c(OC)cccc2[nH]1,3CL,active,34,Ki,WO2021205290A1,10 nM to 100 nM
O=C(Nc1ccc(NC(=O)c2cc(B(O)O)cc([N+](=O)[O-])c2)cc1)c1cc(B(O)O)cc([N+](=O)[O-])c1,3CL,active,22,Ki,WO2018042343A2,10 nM to 100 nM
O=C(On1nnc2ccccc21)c1cc2cc(F)ccc2[nH]1,3CL,active,13.8,Ki,WO2021188620A1,10 nM to 100 nM
O=C[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@@H]1C2CCCC2CN1C(=O)COc1ccc(Cl)cc1F,3CL,active,34.7,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Oc1cncc(Cl)c1)c1cc2ccccc2[nH]1,3CL,active,65,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN(CC)c1ccc(C(=O)On2nnc3ccccc32)cc1,3CL,active,11.1,Ki,WO2021212039A1,10 nM to 100 nM
O=C[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@@H]1C2CCCC2CN1C(=O)CCc1cccc(F)c1,3CL,active,7.6,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3c(C)cc(C#N)cc3C)cc12,3CL,active,8,Ki,WO2021205290A1,1 nM to 10 nM
Cc1cc(-c2ccc(N/N=C3\C=Cc4c(S(=O)(=O)[O-])cc(S(=O)(=O)[O-])c(N)c4C3=O)c(C)c2)ccc1N/N=C1\C=Cc2c(S(=O)(=O)[O-])cc(S(=O)(=O)[O-])c(N)c2C1=O,3CL,active,73,Ki,WO2021205290A1,10 nM to 100 nM
CN(C)c1ccc(C(=O)On2nnc3ccccc32)cc1,3CL,active,17.4,Ki,WO2021188620A1,10 nM to 100 nM
CC(C)C[C@H](NC(=O)[C@H](CN1CCC(F)CC1)NC(=O)OCc1ccccc1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)C(=O)NC(C)C,3CL,active,7,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)[C@H](NC(=O)C(F)(F)F)C(=O)N1C[C@H]2[C@@H]([C@H]1C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O)[C@@]2(C)CO,3CL,active,92,Ki,WO2018042343A2,10 nM to 100 nM
CC1(C)C2CN(C(=O)COc3ccc(Cl)cc3Cl)[C@H](C(=O)N[C@H](C=O)C[C@@H]3CCNC3=O)C21,3CL,active,13,ic50,WO2018042343A2, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)(C)C)C(=O)N[C@H](C#N)C[C@@H]3CCNC3=O)cc12,3CL,active,56,Ki,WO2018042343A2,10 nM to 100 nM
CC(C)(C)C[C@H](NC(=O)c1cc2cccc(C(F)(F)F)c2[nH]1)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,active,52,Ki,WO2018042343A2,10 nM to 100 nM
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3ccc(F)cc3)cc12,3CL,active,16,Ki,WO2018042343A2,10 nM to 100 nM
CC(C)(C)C[C@H](NC(=O)[C@H]1CCCO1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)CO,3CL,active,91,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)c1cc2c(O)cccc2[nH]1)C(=O)C[C@@H](C[C@@H]1CCNC1=O)C(=O)c1nc2ccccc2s1,3CL,active,26,Ki,WO2021219089A1,10 nM to 100 nM
O=C[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H]1C2CCCC2CN1C(=O)COc1ccc(Cl)c(Cl)c1,3CL,active,30,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3cn(C)nc3C)cc12,3CL,active,92,Ki,WO2021205290A1,10 nM to 100 nM
O=C(Oc1cncc(Cl)c1)c1cc2ccccc2s1,3CL,active,95,ic50,WO2021151265A1, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)N[C@H](C(=O)N1C[C@H]2[C@@H]([C@H]1C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O)C2(C)C)C(C)(C)C,3CL,active,1,Ki,WO2021212039A1,1 nM to 10 nM
O=C[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cc2ccccc2[nH]1,3CL,active,8,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCCCC1)C(=O)[C@H](C[C@@H]1CCCNC1=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)c1cc2ccccc2o1,3CL,active,0.1,ic50,CN113181339A, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)C(C)(C)C)cc12,3CL,active,94,Ki,WO2021212039A1,10 nM to 100 nM
COc1ccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)C[C@@H](C[C@@H]3CCNC3=O)C(=O)c3nc4ccccc4s3)cc2c1,3CL,active,67,Ki,WO2021212039A1,10 nM to 100 nM
CC(C)C[C@H](NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)c1ncc(-c2ccccc2)s1,3CL,active,60,Ki,WO2021219089A1,10 nM to 100 nM
O=C(Oc1cncc(Cl)c1)c1ccc(-c2ccc(Cl)cc2)o1,3CL,active,63,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](Cc1cccc(F)c1)NC(=O)c1cc2ccccc2[nH]1,3CL,active,40,ic50,US20150133368A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)[C@H](NC(=O)c1cncc(F)c1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C=O)C[C@@H]1CCNC1=O,3CL,active,35,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(O)CC1N[Zn]2(NC(CC(=O)O)C(=O)O2)OC1=O,3CL,active,50,Ki,WO2021151265A1,10 nM to 100 nM
CC(C)C[C@H](NC(=O)[C@H](CN1CCOCC1)NC(=O)OCc1ccccc1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)C(=O)NC(C)C,3CL,active,7,ic50,WO2018042343A2, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3ccccn3)cc12,3CL,active,4,Ki,WO2021205290A1,1 nM to 10 nM
O=C(NC1CCC(F)(F)CC1)[C@@H](c1cncnc1)N(C(=O)[C@@H](F)Cl)c1ccc(-c2cncs2)cc1,3CL,active,60,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)C2CN(C(=O)COc3ccc(Br)cc3Cl)[C@H](C(=O)N[C@H](C=O)C[C@@H]3CCNC3=O)C21,3CL,active,13.3,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3cnn(C)c3)cc12,3CL,active,91,Ki,WO2021205290A1,10 nM to 100 nM
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3ccncc3)cc12,3CL,active,1,Ki,WO2021205290A1,1 nM to 10 nM
CC(C)(C)[C@H](NC(=O)C(F)(F)F)C(=O)N1C[C@H]2[C@@H]([C@H]1C(=O)N[C@H](C#N)C[C@@H]1CC(=O)NC1=O)C2(C)C,3CL,active,4,Ki,WO2021205290A1,1 nM to 10 nM
COc1c(O)ccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C#N)C[C@@H]3CCNC3=O)cc12,3CL,active,74,Ki,CN113181339A,10 nM to 100 nM
COc1cccc(OC)c1C(=O)OCC(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC(C)C)NC(=O)c1cc2c(OC)cccc2[nH]1,3CL,active,16,Ki,WO2021212039A1,10 nM to 100 nM
O=c1c2ccccc2sn1Cc1ccco1,3CL,active,78,Ki,WO2021219089A1,10 nM to 100 nM
CC(C)(C)C[C@H](NC(=O)c1cc2ccccc2[nH]1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)CO,3CL,active,20,ic50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)C[C@H](NC(=O)c1cc2cccc(Cl)c2[nH]1)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,active,32,Ki,WO2021205290A1,10 nM to 100 nM
CC1(C)C2CN(C(=O)COc3ccc(F)c(F)c3)[C@H](C(=O)N[C@H](C=O)C[C@@H]3CCNC3=O)C21,3CL,active,13.2,ic50,WO2021151265A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@@H]1C2CCCC2CN1C(=O)CCc1ccc(F)c(F)c1,3CL,active,17.4,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)[C@H](NC(=O)[C@H](C)NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)[C@@H](O)[C@H](O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@@H](C)NC(=O)OCc1ccccc1)C(C)C,3CL,active,73,Ki,WO2018042343A2,10 nM to 100 nM
COc1ccc(OCC(=O)N2CC3C([C@H]2C(=O)N[C@H](C=O)C[C@@H]2CCNC2=O)C3(C)C)cc1F,3CL,active,37.2,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(Cl)ccc1OCC(=O)N1CC2CCCC2[C@H]1C(=O)N[C@H](C=O)C[C@@H]1CCNC1=O,3CL,active,19.7,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(CO)[C@H](NC(=O)C(F)(F)F)C(=O)N1C[C@H]2[C@@H]([C@H]1C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O)C2(C)C,3CL,active,3,Ki,WO2021212039A1,1 nM to 10 nM
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3c(C)ncnc3C)cc12,3CL,active,1,Ki,WO2021205290A1,1 nM to 10 nM
O=C(Oc1cncc(Cl)c1)c1cccc2[nH]ccc12,3CL,active,30,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3c(C)cccc3C)cc12,3CL,active,3,Ki,CN113181339A,1 nM to 10 nM
CC(C)C[C@H](NC(=O)c1cc2cccc(C(F)(F)F)c2[nH]1)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,active,73,Ki,WO2021219089A1,10 nM to 100 nM
COc1ccc(F)c2[nH]c(C(=O)N[C@@H](CC(C)(C)C)C(=O)N[C@H](C#N)C[C@@H]3CCNC3=O)cc12,3CL,active,5,Ki,WO2021219089A1,1 nM to 10 nM
Cc1c(C(=O)N[C@@H](CC(C)(C)C)C(=O)N[C@H](C#N)C[C@@H]2CCNC2=O)sc2ncc(C(F)(F)F)n12,3CL,active,83,Ki,WO2021219089A1,10 nM to 100 nM
O=C(NC1CCC(F)(F)CC1)C(c1cncnc1)N(C(=O)CCl)c1ccc(-c2cncs2)cc1,3CL,active,78,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3c(C)cccc3F)cc12,3CL,active,9,Ki,WO2021205290A1,1 nM to 10 nM
CC1(C)C2CN(C(=O)[C@@H](NC(=O)C(F)(F)F)C(C)(C)C)[C@H](C(=O)N[C@H](C#N)C[C@@H]3CCNC3=O)C21,3CL,active,3.11,Ki,WO2021219089A1,1 nM to 10 nM
Cc1ccc(CC(=O)N[C@H](C(=O)N2C[C@H](C(F)(F)F)C[C@H]2C(=O)N[C@H](C#N)C[C@@H]2CCNC2=O)C(C)(C)C)cc1,3CL,active,4,Ki,WO2021219089A1,1 nM to 10 nM
O=C[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@@H]1C2CCCC2CN1C(=O)COc1ccc(Cl)cc1,3CL,active,9.2,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(O)S(=O)(=O)O,3CL,active,30,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCCNC(=O)C(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CN1CCC(F)(F)CC1)NC(=O)OCc1ccccc1,3CL,active,60,ec50,WO2021191827A1, not Ki or Kd; not used in NCI fingerprint analysis
COCC(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC(C)(C)C)NC(=O)c1cc2c(OC)cccc2[nH]1,3CL,active,35,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(N[C@H]1CCC(F)(F)C1)C(c1cncnc1)N(C(=O)CCl)c1ccc(-c2cncs2)cc1,3CL,active,90,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)c1nc2ccccc2[nH]1)C(=O)C[C@@H](C[C@@H]1CCNC1=O)C(=O)c1nc2ccccc2s1,3CL,active,22,Ki,WO2021151265A1,10 nM to 100 nM
CC(C)C[C@H](NC(=O)[C@@H](NC(=O)COc1cccc(N(C)C)c1)C(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)c1nc2ccccc2s1,3CL,active,3,Ki,WO2021188620A1,1 nM to 10 nM
CC(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C=O)Cc1c[nH]cn1)C(C)C,3CL,active,98,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COCc3ccccc3)cc12,3CL,active,32,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3ccc(C)cc3)cc12,3CL,active,18,Ki,WO2021212039A1,10 nM to 100 nM
CC(C)C[C@H](NC(=O)c1nc2ccccc2[nH]1)C(=O)N[C@H](C=O)C[C@@H]1CCNC1=O,3CL,active,30,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)c1cc2c(OC(F)(F)F)cccc2[nH]1)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,active,83,Ki,WO2021212039A1,10 nM to 100 nM
CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@H](C=O)C[C@@H]1CCNC1=O,3CL,active,70,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(On1nnc2ccccc21)c1cc2ccccc2[nH]1,3CL,active,12.3,Ki,WO2005113580A1,10 nM to 100 nM
CC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CC1CCCCC1)C(=O)N[C@H](C=O)Cc1c[nH]cn1)C(C)C,3CL,active,65,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3c(C)nc(C4CCOCC4)nc3C)cc12,3CL,active,6,Ki,WO2021205290A1,1 nM to 10 nM
CC(C)(C)[C@H](NC(=O)COc1ccc(F)cc1)C(=O)N1C[C@H]2[C@@H]([C@H]1C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O)C2(C)C,3CL,active,7,Ki,WO2021219089A1,1 nM to 10 nM
COc1cccc2[nH]c(C(=O)N[C@@H](CCC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)CO)cc12,3CL,active,33,Ki,WO2021219089A1,10 nM to 100 nM
O=C[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@@H]1C2CCCC2CN1C(=O)COc1ccc2c(c1)OCCO2,3CL,active,93.5,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)C[C@H](NC(=O)c1cc2ccc(Cl)cc2[nH]1)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,active,49,Ki,WO2005113580A1,10 nM to 100 nM
COC(=O)/C=C/[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)NC(=O)C(C)(C)C,3CL,active,38,Ki,WO2005113580A1,10 nM to 100 nM
COc1ccc(OCC(=O)N2CC3CCCC3[C@H]2C(=O)N[C@H](C=O)C[C@@H]2CCNC2=O)cc1,3CL,active,36.2,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Cn1nnc2ccccc21)N(Cc1ccsc1)c1ccc(-c2ccccc2)cc1,3CL,active,51,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCCC1CCC(OC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C=O)C[C@@H]2CCNC2=O)CC1,3CL,active,10,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)c1cc2cccc(Cl)c2[nH]1)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,active,34,Ki,WO2021188620A1,10 nM to 100 nM
CC(C)C[C@H](NC(=O)c1cc2ccccc2[nH]1)C(=O)C[C@@H](C[C@@H]1CCNC1=O)C(=O)c1nc2ccccc2s1,3CL,active,65,Ki,WO2021212039A1,10 nM to 100 nM
CC(C)C[C@H](NC(=O)c1cc2c(Cl)cccc2[nH]1)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,active,38,Ki,WO2021188620A1,10 nM to 100 nM
CC(C)[C@H](NS(=O)(=O)C(F)(F)F)C(=O)N1CC[C@@H](C(C)(C)C)C[C@H]1C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,active,17,Ki,WO2021212039A1,10 nM to 100 nM
O=C(NC1CCC(F)(F)CC1)[C@@H](c1cncnc1)N(C(=O)CCl)c1ccc(-c2cncs2)cc1,3CL,active,50,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)Oc3c(Cl)cccc3Cl)cc12,3CL,active,0,Ki,WO2021212039A1,Below 1 nM
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3c(F)cccc3F)cc12,3CL,active,1,Ki,WO2021212039A1,1 nM to 10 nM
O=C(On1nnc2ccccc21)c1ccc2[nH]cnc2c1,3CL,active,22.9,Ki,WO2021212039A1,10 nM to 100 nM
CC(C)[C@H](NC(=O)C(F)(F)F)C(=O)N1C[C@H]2[C@@H]([C@H]1C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O)C2(C)C,3CL,active,13,Ki,WO2005113580A1,10 nM to 100 nM
CC(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CC1CCCCC1)C(=O)NC(C=O)Cc1c[nH]cn1)C(C)C,3CL,active,65,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)c1cc2ccccc2[nH]1)C(=O)N[C@H](C=O)C[C@@H]1CCNC1=O,3CL,active,20,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)N[C@H](C(=O)N1C[C@H]2[C@@H]([C@H]1C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O)C2(C)C)C(C)(C)C,3CL,active,5,Ki,WO2021212039A1,1 nM to 10 nM
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3ccnn3C)cc12,3CL,active,5,Ki,WO2021205290A1,1 nM to 10 nM
CC(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1ccc2cc(Br)ccc2c1,3CL,active,47,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(OC(C)C(=O)N2CC3CCCC3[C@H]2C(=O)N[C@H](C=O)C[C@@H]2CCNC2=O)cc1,3CL,active,69.1,ic50,WO2021205290A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC3CCCCC3)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)CO)cc12,3CL,active,25,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)c1ccc(C(=O)N[C@@H](Cc2ccccc2)C(=O)Nc2ccc([N+](=O)[O-])cc2Cl)cc1,3CL,active,30,Ki,WO2021205290A1,10 nM to 100 nM
O=C(NC1CCC(F)(F)CC1)[C@@H](c1cncnc1)N(C(=O)CCl)c1ccc(-c2ccno2)cc1,3CL,active,63,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)[C@H](NC(=O)C(F)(F)F)C(=O)N1C[C@H](C(F)(F)F)C[C@H]1C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,active,4,Ki,WO2021219089A1,1 nM to 10 nM
CCC(C)(C)NC(=O)[C@@H](c1ccn(C)c1)N(C(=O)Cn1nnc2ccccc21)c1ccc(NC(C)=O)cc1,3CL,active,30,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)[C@H]2CN(C(=O)[C@H](Cn3cccn3)NC(=O)C(F)(F)F)[C@H](C(=O)N[C@H](C#N)C[C@@H]3CCNC3=O)[C@H]21,3CL,active,14,Ki,WO2021219089A1,10 nM to 100 nM
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)[C@H]3CCCN3C)cc12,3CL,active,0,Ki,WO2021205290A1,Below 1 nM
O=C(Oc1cncc(Cl)c1)c1cccc2cc[nH]c12,3CL,active,80,ic50,WO2013049382A3, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)[C@H](NC(=O)C(F)(F)F)C(=O)N1C[C@H]2[C@@H]([C@H]1C(=O)N[C@H](C#N)C[C@@H]1CC(O)NC1=O)C2(C)C,3CL,active,30,Ki,WO2021219089A1,10 nM to 100 nM
CC[C@@H](C)C(=O)OCC(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC(C)C)NC(=O)c1cc2c(OC)cccc2[nH]1,3CL,active,65,Ki,WO2021205290A1,10 nM to 100 nM
N#Cc1cc(OC(F)(F)F)ccc1N(C(=O)CCl)[C@@H](C(=O)NC1CCCCC1)c1cccnc1,3CL,active,80,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](C)C(=O)OCC(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC(C)C)NC(=O)c1cc2c(OC)cccc2[nH]1,3CL,active,66,Ki,WO2021205290A1,10 nM to 100 nM
COc1cccc(C)c1C(=O)OCC(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC(C)C)NC(=O)c1cc2c(OC)cccc2[nH]1,3CL,active,40,Ki,WO2021205290A1,10 nM to 100 nM
CC1(C)[C@H]2CN(C(=O)[C@H](CC(F)F)NC(=O)C(F)(F)F)[C@H](C(=O)N[C@H](C#N)C[C@@H]3CCNC3=O)[C@H]21,3CL,active,11,Ki,WO2018042343A2,10 nM to 100 nM
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)c3nc4ccccc4s3)cc12,3CL,active,6,Ki,WO2021219089A1,1 nM to 10 nM
O=C(N[C@H]1CCOC1)[C@@H](c1cnccn1)N(C(=O)CCl)c1ccc(-c2ccno2)cc1,3CL,active,39,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)C2CN(C(=O)COc3ccc4ccccc4c3)[C@H](C(=O)N[C@H](C=O)C[C@@H]3CCNC3=O)C21,3CL,active,52.1,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)C(C)C)cc12,3CL,active,64,Ki,WO2021205290A1,10 nM to 100 nM
COCC(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CCC(C)C)NC(=O)c1cc2c(OC)cccc2[nH]1,3CL,active,36,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)[C@H]2CN(C(=O)C(CCC(F)(F)F)NC(=O)C(F)(F)F)[C@H](C(=O)N[C@H](C#N)C[C@@H]3CCNC3=O)[C@H]21,3CL,active,18,Ki,CN113197895A,10 nM to 100 nM
O=C[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@@H]1C2CCCC2CN1C(=O)COc1ccc(Cl)cc1Cl,3CL,active,17.2,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)[C@H]3CCCCN3C)cc12,3CL,active,1,Ki,WO2021205290A1,1 nM to 10 nM
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C=O)CCC(=O)N(C)C)cc12,3CL,active,50,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CC1CCCCC1)C(=O)N[C@H](C=O)Cc1c[nH]cn1)C(C)C)C(C)O,3CL,active,98,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3cncn3C)cc12,3CL,active,41,Ki,WO2021205290A1,10 nM to 100 nM
CC1(C)C2CN(C(=O)COc3ccc(Cl)c(Cl)c3)[C@H](C(=O)N[C@H](C=O)C[C@@H]3CCNC3=O)C21,3CL,active,12.4,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCC(F)(F)CC1)[C@@H](c1cnccn1)N(C(=O)CCl)c1ccc(-c2cncs2)cc1,3CL,active,60,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3ccc(C#N)cc3F)cc12,3CL,active,0,Ki,WO2021212039A1,Below 1 nM
CC(=O)c1ccc2c(c1)C(=O)C(=O)N2CCc1cc2ccccc2s1,3CL,active,53,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
COC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)C(=O)NC(C)C,3CL,active,6.8,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)CN(C)C)cc12,3CL,active,3,Ki,WO2021205290A1,1 nM to 10 nM
CC(C)(C)NC(=O)C(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1cccc2ccccc12)NC(=O)OCc1ccc(OCCCN2CCOCC2)cc1,3CL,active,6.6,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)[C@H]2CN(C(=O)[C@@H](NS(=O)(=O)C(F)(F)F)C3CCCCC3)[C@H](C(=O)N[C@H](C#N)C[C@@H]3CCNC3=O)[C@H]21,3CL,active,21,Ki,WO2021212039A1,10 nM to 100 nM
CC(C)C[C@H](NC(=O)c1cc2c(OC(C)C)cccc2[nH]1)C(=O)C[C@@H](C[C@@H]1CCNC1=O)C(=O)c1nc2ccccc2s1,3CL,active,48,Ki,CN113197895A,10 nM to 100 nM
CC(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1ccc2ccccc2c1,3CL,active,45,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC(CCF)CCF)[C@@H](c1cnccn1)N(C(=O)CCl)c1ccc(-c2ccns2)cc1,3CL,active,50,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CCC(C(NC(=O)C(F)(F)F)C(=O)N1C[C@H]2[C@@H]([C@H]1C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O)C2(C)C)C(F)(F)F,3CL,active,11,Ki,WO2021188620A1,10 nM to 100 nM
CC1(C)C2CN(C(=O)CCc3cccc(F)c3)[C@H](C(=O)N[C@H](C=O)C[C@@H]3CCNC3=O)C21,3CL,active,16.5,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C#N)C[C@@H]3CCNC3=O)c(F)c12,3CL,active,53,Ki,WO2021212039A1,10 nM to 100 nM
CC1(C)C2CN(C(=O)COc3cccc(C(F)(F)F)c3)[C@H](C(=O)N[C@H](C=O)C[C@@H]3CCNC3=O)C21,3CL,active,43.3,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)C[C@@H](C[C@@H]3CCNC3=O)C(=O)c3nc4ccccc4s3)cc12,3CL,active,30,Ki,US20150133368A1,10 nM to 100 nM
O=C(N[C@@H]1CCOC1)[C@H](c1cncnc1)N(C(=O)CCl)c1ccc(-c2cnco2)cc1,3CL,medium,450,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)c1c[nH]c2ccccc12)C(=O)C[C@@H](C[C@@H]1CCNC1=O)C(=O)c1nc2ccccc2s1,3CL,medium,680,Ki,WO2005113580A1,Over 100 nM
COc1ccc(OCC(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]2CCNC2=O)C(=O)c2ncc(-c3ccccc3OC)s2)C(C)C)cc1,3CL,medium,470,Ki,WO2021205290A1,Over 100 nM
Cc1nn(C)c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C#N)C[C@@H]2CCNC2=O)c1Cl,3CL,medium,226,Ki,WO2021212039A1,Over 100 nM
O=[N+]([O-])c1ccccc1SSc1ncccn1,3CL,medium,883,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cccc(S(=O)(=O)n2ccc3cc(C(=O)Oc4cncc(Cl)c4)ccc32)c1,3CL,medium,370,ic50,WO2021160220A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)C[C@H](NC(=O)c1cc2ccc(C(F)(F)F)cc2[nH]1)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,medium,227,Ki,WO2021160220A1,Over 100 nM
CC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)Cn1[nH]c(=O)c2c([N+](=O)[O-])cccc2c1=O)C(C)OCc1ccccc1)C(C)C,3CL,medium,600,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(N[C@H]1CCOC1)C(c1cnccn1)N(C(=O)CCl)c1ccc(-c2ccno2)cc1,3CL,medium,150,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CCn1nc(C)c(Br)c1C(=O)N[C@@H](CC(C)(C)C)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,medium,297,Ki,WO2021212039A1,Over 100 nM
CCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C(=O)C(=O)NCc1ccccn1,3CL,medium,130,Ki,WO2021219089A1,Over 100 nM
CSCC[C@@H](C=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O,3CL,medium,400,Ki,WO2021205290A1,Over 100 nM
CC(=O)N1Cc2ccccc2CC1C(=O)Oc1cncc(Cl)c1,3CL,medium,140,ic50,US20150133368A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C(=O)Nc1ccc(N(C(=O)CN2N=NC3=CC=CC32)C(C(=O)NCc2ccccc2)c2ccc(Cl)c(F)c2)cc1,3CL,medium,800,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=[N+]([O-])O[Hg]c1ccccc1,3CL,medium,300,Ki,WO2021212039A1,Over 100 nM
CC(C)C[C@H](NC(=O)OC1CCCCC1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(O)S(=O)(=O)O,3CL,medium,650,ic50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)OC1CCN(S(C)(=O)=O)CC1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(O)S(=O)(=O)O,3CL,medium,500,ic50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Oc1cncc(Cl)c1)c1cscn1,3CL,medium,270,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@@H]1C2CCCC2CN1C(=O)c1cccnc1,3CL,medium,748.5,ic50,WO2021205290A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)Oc1ccccc1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)c1ncc(-c2ccccc2)s1,3CL,medium,660,Ki,WO2021205290A1,Over 100 nM
CC(C)(C)OC(=O)Nc1cccn([C@@H](CC2CC2)C(=O)N[C@@H](C[C@@H]2CCNC2=O)C(=O)C(=O)NCc2ccccc2)c1=O,3CL,medium,472,ic50,WO2021205290A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(N[C@H]1CCOC1)[C@@H](c1cncnc1)N(C(=O)CCl)c1ccc(-c2cnco2)cc1,3CL,medium,340,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1sc2ccccc2c1=O,3CL,medium,780,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCC(F)(F)CC1)C(c1cnccn1)N(C(=O)CCl)c1ccc(-c2cnco2)cc1,3CL,medium,240,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Oc1cncc(Cl)c1)c1ccccc1[N+](=O)[O-],3CL,medium,333,ic50,CN113321650A, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCCCC1)C(c1cccnc1)N(CCc1ccc(Cl)cc1)C(=O)CCl,3CL,medium,940,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COCC(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC(C)C)NC(=O)c1cc2ccccc2[nH]1,3CL,medium,131,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CCS(=O)(=O)N1CCC(NC(=O)C(c2cncnc2)N(C(=O)CCl)c2ccc(-c3cnco3)cc2)CC1,3CL,medium,630,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Oc1cncc(Cl)c1)c1ccc(-c2ccc(Cl)cc2[N+](=O)[O-])o1,3CL,medium,122,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)C1Cc2ccccc2N1)C(=O)C[C@@H](C[C@@H]1CCNC1=O)C(=O)c1nc2ccccc2s1,3CL,medium,120,Ki,WO2021212039A1,Over 100 nM
COC(=O)c1ccc(-n2sc3ccccc3c2=O)cc1,3CL,medium,360,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(/C=C/C(=O)N2CC3CCCC3[C@H]2C(=O)N[C@H](C=O)C[C@@H]2CCNC2=O)c(OC)c1,3CL,medium,195.6,ic50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCCCC1)C(c1cncnc1)N(C(=O)CCl)c1ccc(-c2cnco2)cc1,3CL,medium,290,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)C[C@H](NC(=O)c1cc2c(Cl)cccc2[nH]1)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,medium,104,Ki,WO2021219089A1,Over 100 nM
CC(=O)N[C@@H](C(=O)NC(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N(C)C)C(=O)Cn1[nH]c(=O)c2c([N+](=O)[O-])cccc2c1=O)[C@H](C)OCc1ccccc1)C(C)C,3CL,medium,600,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1,3CL,medium,400,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCCC1CCC(OC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]2CCNC2=O)C(O)S(=O)(=O)O)CC1,3CL,medium,200,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C(=O)N[C@@H](CC(C)(C)C)C(=O)N[C@H](C#N)C[C@@H]2CCNC2=O)sc2nccn12,3CL,medium,798,Ki,WO2021212039A1,Over 100 nM
O=C(Oc1ccc(S(=O)(=O)c2ccc(OC(=O)C(Cl)=C(Cl)Cl)cc2)cc1)C(Cl)=C(Cl)Cl,3CL,medium,900,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N3C[C@H]4[C@@H]([C@H]3C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)c3nc5ccccc5s3)C4(C)C)cc12,3CL,medium,230,Ki,WO2021212039A1,Over 100 nM
O=C(N[C@@H]1CCOC1)[C@@H](c1cncnc1)N(C(=O)CCl)c1ccc(-c2cnco2)cc1,3CL,medium,160,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCC(F)(F)CC1)[C@H](c1cnccn1)N(C(=O)CCl)c1ccc(-c2ccns2)cc1,3CL,medium,210,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(N[C@H]1CCOC1)[C@H](c1cncnc1)N(C(=O)CCl)c1ccc(-c2cncs2)cc1,3CL,medium,440,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Oc1cncc(Cl)c1)c1ccc2[nH]ccc2c1,3CL,medium,310,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COC(C(=O)N[C@@H](CC(C)(C)C)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O)C1CCCCC1,3CL,medium,917,Ki,CN105837487A,Over 100 nM
Cc1cc(-c2cnco2)ccc1N(C(=O)CCl)C(C(=O)NC1CCCCC1)c1cncnc1,3CL,medium,260,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(OC1CCCCC1)C(=O)N[C@@H](CC(C)(C)C)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,medium,690,Ki,WO2021219089A1,Over 100 nM
O=C(Oc1cncc(Cl)c1)c1cccs1,3CL,medium,500,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)n1ccc2c(C(=O)Oc3cncc(Cl)c3)cccc21,3CL,not active,1000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1nc(-c2ccc(C(F)(F)F)cc2)nc2c(=O)n(C)c(=O)nc1-2,3CL,medium,260,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(N[C@H]1CCC(F)(F)C1)[C@H](c1cncnc1)N(C(=O)CCl)c1ccc(-c2cncs2)cc1,3CL,medium,980,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
N#Cc1cc(OC(F)(F)F)ccc1N(C(=O)CCl)C(C(=O)NC1CCCCC1)c1cccnc1,3CL,medium,240,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(C)nc(SSc2ccccc2[N+](=O)[O-])n1,3CL,medium,921,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
[O-][n+]1ccccc1S[Zn]Sc1cccc[n+]1[O-],3CL,medium,170,Ki,WO2021212039A1,Over 100 nM
O=c1[nH]sc2ccccc12,3CL,medium,660,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCS(=O)(=O)CC1)C(c1cncnc1)N(C(=O)CCl)c1ccc(-c2cnco2)cc1,3CL,medium,600,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NCCc1ccccc1)C(c1cncnc1)N(C(=O)CCl)c1ccc(-c2cnco2)cc1,3CL,medium,600,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(N[C@@H](CC1CCCCC1)C(=O)N[C@@H](CC1CCNC1=O)C(O)P(=O)(OCc1ccccc1)OCc1ccccc1)OCc1ccccc1,3CL,medium,600,ec50,US20150133368A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(N[C@@H](Cc1ccc2ccccc2c1)C(=O)CCl)OCc1ccccc1,3CL,medium,370,Ki,WO2021151265A1,Over 100 nM
CC(=O)O[Hg]c1ccccc1,3CL,medium,110,Ki,CN113321650A,Over 100 nM
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)C3CC3)cc12,3CL,medium,180,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)[C@@H](C(=O)N[C@@H](CC(C)(C)C)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O)c1ccccc1,3CL,medium,241,Ki,WO2021205298A1,Over 100 nM
COc1cccc(C(=O)Oc2cncc(Cl)c2)c1,3CL,medium,340,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCOC1)C(c1cncnc1)N(C(=O)CCl)c1ccc(-c2cnco2)cc1,3CL,medium,220,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN(C(=S)S[Zn]SC(=S)N(CC)c1ccccc1)c1ccccc1,3CL,not active,1000,Ki,CN113181339A,Over 100 nM
Brc1ccc(SSc2ncccn2)cc1,3CL,medium,697,ic50,WO2021151265A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CCC(F)(F)F)C(=O)N[C@H](C#N)C[C@@H]3CCNC3=O)cc12,3CL,medium,302,Ki,WO2018042343A2,Over 100 nM
O=C[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)/C=C/c1ccc(Cl)cc1F,3CL,medium,200,ic50,WO2018042343A2, not Ki or Kd; not used in NCI fingerprint analysis
CSCCC(C=O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(C)=O,3CL,medium,970,ic50,WO2018042343A2, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3cn(C)cn3)cc12,3CL,medium,152,Ki,WO2021205290A1,Over 100 nM
Cc1nc(C(F)(F)F)sc1C(=O)N[C@@H](CC(C)(C)C)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,medium,254,Ki,WO2018042343A2,Over 100 nM
CC(C)Cn1sc2ccccc2c1=O,3CL,medium,480,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)[C@H](CN1CCC(C(F)(F)F)CC1)NC(=O)OCc1ccccc1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)C(=O)NC(C)C,3CL,medium,140,ec50,WO2021191827A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)OC1CCC(F)(F)CC1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(O)S(=O)(=O)O,3CL,medium,410,ic50,WO2018042343A2, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCCCC1)C(c1cccnc1)N(C(=O)CCl)c1ccc(-c2cnco2)cc1,3CL,medium,680,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)[C@H](NC(=O)C(F)(F)F)C(=O)N1C[C@H]2[C@@H]([C@H]1C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O)[C@]2(C)CO,3CL,medium,139,Ki,CN113321650A,Over 100 nM
O=C(NC1CCC(F)(F)CC1)C(c1ccnnc1)N(C(=O)CCl)c1ccc(-c2cncs2)cc1,3CL,medium,130,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(O)CCn1[se]c2ccccc2c1=O,3CL,medium,350,ic50,WO2021151265A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(/C=C/c1ccccc1)N[C@@H](CC1CC1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)C(=O)NCc1ccccc1,3CL,medium,240,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)c1ccc(/C=C/C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](C=O)C[C@@H]2CCNC2=O)cc1,3CL,medium,500,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)C[C@H](NC(=O)CC1CC(F)(F)C1)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,medium,539,Ki,CN113181339A,Over 100 nM
CCOCC(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC(C)(C)C)NC(=O)c1cc2ccccc2[nH]1,3CL,medium,112,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)[C@@H](NC(=O)COc1ccc(N(C)C)cc1)C(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)c1nc2ccccc2s1,3CL,medium,650,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1C(=O)N(CCc2cc3ccccc3s2)c2ccc(I)cc21,3CL,medium,950,ic50,US20150133368A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)/C=C/c1ccccc1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)C(=O)NCc1ccccc1,3CL,medium,330,ic50,US20150133368A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCOCC1)C(c1cncnc1)N(C(=O)CCl)c1ccc(-c2cnco2)cc1,3CL,medium,430,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CC2(C1)CS(=O)(=O)C2)C(c1cncnc1)N(C(=O)CCl)c1ccc(-c2cnco2)cc1,3CL,medium,660,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=c1c2ccccc2[se]n1CCO,3CL,medium,650,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=c1c2ccccc2sn1-c1ccccc1,3CL,medium,490,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1nn(C)c(C(=O)N[C@@H](CC(C)(C)C)C(=O)N[C@H](C#N)C[C@@H]2CCNC2=O)c1Cl,3CL,medium,176,Ki,WO2021212039A1,Over 100 nM
CCOP(=O)(OCC)C(O)[C@H](CC1CCNC1=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1ccccc1,3CL,medium,250,ec50,US20150133368A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@@H]1C2CCCC2CN1C(=O)c1cc2ccccn2n1,3CL,medium,298.8,ic50,US20150133368A1, not Ki or Kd; not used in NCI fingerprint analysis
CCC[C@H](NC(=O)[C@@H](NC(=O)c1cc(C)on1)C(C)OC(C)(C)C)C(=O)N[C@H](/C=C/C(=O)OCC)C[C@@H]1CCNC1=O,3CL,medium,880,Ki,US20150133368A1,Over 100 nM
COCC(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC(C)(C)C)NC(=O)c1cc2ccccc2[nH]1,3CL,medium,105,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)C3(C)CC3)cc12,3CL,medium,104,Ki,WO2021205290A1,Over 100 nM
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)CN=[N+]=[N-])cc12,3CL,medium,101,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CC(F)(F)C1)C(c1cncnc1)N(C(=O)CCl)c1ccc(-c2cnco2)cc1,3CL,medium,520,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=c1c2ccccc2sn1CCO,3CL,medium,410,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=c1c2ccccc2sn1CCCCc1ccccc1,3CL,medium,410,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)OC1(Cc2ccccc2)CCN(C(=O)OC(C)(C)C)CC1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(O)S(=O)(=O)O,3CL,medium,600,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)[C@H](NC(=O)C(F)(F)F)C(=O)N1C[C@H]2[C@@H]([C@H]1C(=O)N[C@@H](C#N)C[C@@H]1CCNC1=O)C2(C)C,3CL,medium,844,Ki,WO2021212039A1,Over 100 nM
CCCC1CCC(OC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]2CCNC2=O)C(O)S(=O)(=O)O)CC1,3CL,medium,230,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3c(C)nn(C)c3C)cc12,3CL,medium,255,Ki,WO2021205290A1,Over 100 nM
Cc1cccc(CCN(C(=O)CCl)C(C(=O)NC2CCCCC2)c2cccnc2)c1,3CL,not active,1000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCCCC1)C(c1cccnc1)N(CCc1ccccc1)C(=O)CCl,3CL,medium,980,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)c1ccc(/C=C/C(=O)N2CC3CCCC3[C@H]2C(=O)N[C@H](C=O)C[C@@H]2CCNC2=O)cc1,3CL,medium,375,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
COC(C(=O)N[C@@H](CC(C)(C)C)C(=O)N[C@@H](C#N)C[C@@H]1CCNC1=O)C1CCCCC1,3CL,medium,254,Ki,WO2021188620A1,Over 100 nM
O=C(Oc1cncc(Cl)c1)c1ccc(Cl)cc1,3CL,medium,434,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)/C=C/[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)/C=C/c1ccc(N(C)C)cc1,3CL,medium,180,ec50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CC2(C1)CC(F)(F)C2)C(c1cncnc1)N(C(=O)CCl)c1ccc(-c2cnco2)cc1,3CL,medium,530,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=c1c2ccccc2[se]n1-c1ccccc1,3CL,medium,520,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)[C@H](Cc1cccc2ccccc12)NC(=O)OCc1ccccc1)C(=O)N[C@H](C=O)CC1CCNC1=O,3CL,medium,230,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)=O,3CL,medium,970,ic50,CN113181339A, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)OC1CCCCC1)C(=O)N[C@H](C=O)C[C@@H]1CCNC1=O,3CL,medium,820,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@@H]1C2CCCC2CN1C(=O)c1cc2ccccc2[nH]1,3CL,medium,153.1,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=c1c2ccccc2[se]n1-c1ccc([N+](=O)[O-])cc1,3CL,medium,260,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)/C=C/c1cccc(Br)c1,3CL,medium,700,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(-n2sc3ccccc3c2=O)cc1,3CL,medium,330,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCCOP(=O)(OCCCC)C(O)[C@H](CC1CCNC1=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1ccccc1,3CL,medium,500,ec50,US20150133368A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCOCC1)C(c1cccnc1)N(C(=O)CCl)c1ccc(-c2cnco2)cc1,3CL,medium,840,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)[C@H](Cc1cccc2ccccc12)NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC1CCNC1=O)C(=O)C(=O)NC(C)C,3CL,medium,610,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)CCl)C(C(=O)NC2CCCCC2)c2cnccn2)cc1,3CL,medium,280,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Oc1cncc(Cl)c1)c1ccc2cc[nH]c2c1,3CL,medium,230,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCOCC1)C(c1cnccn1)N(C(=O)CCl)c1ccc(-c2cnco2)cc1,3CL,medium,410,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CCn1nc(C)c(Br)c1C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,medium,173,Ki,WO2021212039A1,Over 100 nM
CCOC(=O)/C=C/[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)/C=C\c1ccc(N(C)C)cc1,3CL,medium,520,Ki,WO2021188620A1,Over 100 nM
O=C(N[C@H]1CCOC1)C(c1cncnc1)N(C(=O)CCl)c1ccc(-c2cnco2)cc1,3CL,medium,270,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)/C=C\c1ccccc1)C(=O)N[C@H](C=O)C[C@@H]1CCCNC1=O,3CL,medium,508,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
Clc1ccc(SSc2ncccn2)cc1,3CL,medium,684,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)/C=C/[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C,3CL,medium,660,Ki,WO2021188620A1,Over 100 nM
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)C3(C)CCCCC3)cc12,3CL,medium,139,Ki,WO2021205290A1,Over 100 nM
O=C(O)Cn1[se]c2ccccc2c1=O,3CL,medium,410,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)[C@@H](NC(=O)COc1cccc(N(C)C)c1)C(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)c1ncc(-c2ccccc2)s1,3CL,medium,170,Ki,WO2021205290A1,Over 100 nM
O=C(N[C@H]1CCOC1)C(c1cncnc1)N(C(=O)CCl)c1ccc(-c2cncs2)cc1,3CL,medium,120,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cnc(C(=O)[C@H](C[C@@H]2CCNC2=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)COc2cccc(N(C)C)c2)C(C)C)s1,3CL,medium,330,Ki,WO2018042343A2,Over 100 nM
O=C(NC1CCCCC1)C(c1cccnc1)N(CCc1cccc(Cl)c1)C(=O)CCl,3CL,medium,660,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1C[N+]23CC(=O)O[Zn]2(O1)OC(=O)C3,3CL,medium,320,Ki,WO2005113580A1,Over 100 nM
CC(C)(C)C[C@H](NC(=O)c1c(Cl)cccc1Cl)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,medium,439,Ki,WO2021212039A1,Over 100 nM
COc1ccc(OCC(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]2CCNC2=O)C(=O)c2ncc(-c3ccccc3)s2)C(C)C)cc1,3CL,medium,270,Ki,WO2021212039A1,Over 100 nM
NC(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1ccc2ccccc2c1,3CL,medium,370,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NCc1ccccc1)C(=O)[C@H](C[C@@H]1CCCNC1=O)NC(=O)[C@H](Cc1ccc(F)cc1)NC(=O)c1cc2ccccc2o1,3CL,medium,297,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCC(F)(F)CC1)[C@H](c1cncnc1)N(C(=O)CCl)c1ccc(-c2ccno2)cc1,3CL,medium,530,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(C)c(C(=O)OCC(=O)[C@H](C[C@@H]2CCNC2=O)NC(=O)[C@H](CC(C)C)NC(=O)c2cc3c(OC)cccc3[nH]2)c(C)c1,3CL,medium,117,Ki,WO2021205290A1,Over 100 nM
Nc1ccccc1-n1sc2ccccc2c1=O,3CL,medium,130,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COCc3ccccc3)cc12,3CL,medium,927,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC3CCCCC3)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COCc3ccccc3)cc12,3CL,medium,133,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCCCC1)C(c1cnccn1)N(C(=O)CCl)c1ccc(-c2cnco2)cc1,3CL,medium,400,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)OC1CCC(c2ccccc2)CC1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(O)S(=O)(=O)O,3CL,medium,600,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NCc1ccccc1)C(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)c1ccc2ccccc2n1,3CL,medium,581,ec50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCn1sc2ccccc2c1=O,3CL,medium,730,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1C(=O)N(Cc2cc3ccccc3s2)c2ccc(I)cc21,3CL,medium,950,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCC(F)(F)CC1)[C@H](c1cncnc1)N(C(=O)CCl)c1ccc(-c2cncs2)cc1,3CL,medium,430,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1c(F)ccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C#N)C[C@@H]3CCNC3=O)c(F)c12,3CL,medium,208,Ki,WO2021219089A1,Over 100 nM
CC(C)C[C@H](NC(=O)OC1CCC(F)(F)CC1)C(=O)N[C@H](C=O)C[C@@H]1CCNC1=O,3CL,medium,430,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(C(F)(F)F)c(C(F)(F)F)c2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C#N)C[C@@H]3CCNC3=O)c(C(F)(F)F)c12,3CL,medium,359,Ki,WO2005113580A1,Over 100 nM
COc1cccc(OCC(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]2CCNC2=O)C(=O)c2nc3ccccc3s2)C(C)C)c1,3CL,medium,750,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)CCl)C(C(=O)NC2CCCCC2)c2cncnc2)cc1,3CL,medium,620,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C#N)C[C@@H]3CCNC3=O)c(C(C)=O)c12,3CL,medium,356,Ki,CN113197895A,Over 100 nM
O=C(NCc1ccco1)c1ccc(-n2sc3ccccc3c2=O)cc1,3CL,medium,380,ic50,WO2021151265A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(N[C@@H]1CCOC1)C(c1cncnc1)N(C(=O)CCl)c1ccc(-c2cnco2)cc1,3CL,medium,200,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)c1cc2ccc(C(F)(F)F)cc2[nH]1)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,medium,302,Ki,WO2021219089A1,Over 100 nM
CC(C)(C)c1ccc(N(C(=O)CCl)C(C)(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,medium,900,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)c1ccc(NC(=O)[C@H](c2cncnc2)N(C(=O)CCl)c2ccc(-c3cncs3)cc2)[nH]1,3CL,medium,170,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(O)c1ccc(-n2[se]c3ccccc3c2=O)cc1,3CL,medium,130,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCC(F)(F)CC1)[C@@H](c1cncnc1)N(C(=O)CCl)c1ccc(-c2ccccc2)cc1,3CL,medium,300,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)[C@@H](C(=O)N[C@@H](CC(C)(C)C)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O)c1cccc(C(F)(F)F)c1,3CL,medium,333,ec50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3ncn(C)c3C)cc12,3CL,medium,306,Ki,WO2021205290A1,Over 100 nM
O=C(NC1CCCCC1)C(c1cccnc1)N(C(=O)CCl)c1ccc(N2CCCC2)cc1,3CL,medium,980,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Oc1cncc(Cl)c1)c1ccncc1,3CL,medium,164,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)OC(=O)C[C@H](NC(=O)OCc1ccccc1)C(=O)CBr,3CL,medium,400,Ki,WO2021212039A1,Over 100 nM
O=C(N[C@H]1CCOC1)[C@@H](c1cncnc1)N(C(=O)CCl)c1ccc(-c2cncs2)cc1,3CL,medium,140,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Oc1cncc(Cl)c1)c1ccc(-c2cccc([N+](=O)[O-])c2)o1,3CL,medium,500,ic50,WO2013049382A3, not Ki or Kd; not used in NCI fingerprint analysis
CC1(NC(=O)C(c2cncnc2)N(C(=O)CCl)c2ccc(-c3cnco3)cc2)COC1,3CL,medium,570,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1C(=O)N(Cc2cc3ccccc3s2)c2c(Br)cccc21,3CL,medium,980,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)OCCc1cccc(Cl)c1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(O)S(=O)(=O)O,3CL,medium,700,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCS(=O)(=O)N1CCC(NC(=O)C(c2cnccn2)N(C(=O)CCl)c2ccc(-c3cnco3)cc2)CC1,3CL,medium,570,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=c1c2ccccc2sn1Cc1ccccc1,3CL,medium,170,ic50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
O=c1cc(-c2ccccc2)oc2cc(O)c(O)c(O)c12,3CL,medium,940,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)C[C@H](NC(=O)c1cc2cc(C(F)(F)F)ccc2[nH]1)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,medium,192,Ki,WO2021212039A1,Over 100 nM
O=C(NC1CCC(F)(F)CC1)C(c1cnccn1)N(C(=O)CCl)c1ccc(-c2ccno2)cc1,3CL,medium,100,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC[Hg]Sc1ccccc1C(=O)[O-],3CL,medium,600,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc2cc(C(=O)N[C@@H](CC(C)C)C(=O)C[C@@H](C[C@@H]3CCNC3=O)C(=O)c3nc4ccccc4s3)[nH]c2c1,3CL,medium,330,Ki,WO2021188620A1,Over 100 nM
O=C(Oc1cncc(Cl)c1)c1cccnc1,3CL,medium,697,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)C2CN(C(=O)c3ccc4ccccc4c3)[C@H](C(=O)N[C@H](C=O)C[C@@H]3CCNC3=O)C21,3CL,medium,453,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOCCN(C)C(=O)CC[C@@H](C=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,medium,980,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@@H](C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)CO)N(C)C(=O)c1cc2ccccc2[nH]1,3CL,medium,152,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Oc1cncc(Cl)c1)c1cc2ccccc2oc1=O,3CL,medium,108,ic50,WO2021205290A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)C[C@H](NC(=O)c1cc2cc(Cl)ccc2[nH]1)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,medium,151,Ki,WO2021212039A1,Over 100 nM
O=C1C(=O)N(CCc2cc3ccccc3s2)c2c(Br)cccc21,3CL,medium,980,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@](C(=O)NC1CCC(F)(F)CC1)(c1cnccn1)N(C(=O)CCl)c1ccc(-c2ccns2)cc1,3CL,medium,130,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3c(Cl)cccc3Cl)cc12,3CL,medium,350,ec50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCS(=O)(=O)CC1)C(c1cnccn1)N(C(=O)CCl)c1ccc(-c2cnco2)cc1,3CL,medium,450,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(NC(=O)C(c2cncnc2)N(C(=O)CCl)c2ccc(-c3cnco3)cc2)CC1,3CL,medium,500,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCC(F)(F)CC1)C(c1cncnc1)N(C(=O)C(F)Cl)c1ccc(-c2cncs2)cc1,3CL,medium,330,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CC1CCCCC1)C(=O)NC(C=O)Cc1c[nH]cn1)C(C)C,3CL,medium,270,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)OCC1CCC(F)(F)CC1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(O)S(=O)(=O)O,3CL,medium,450,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CC2(COC2)C1)C(c1cncnc1)N(C(=O)CCl)c1ccc(-c2cnco2)cc1,3CL,medium,990,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCS(=O)(=O)CC1)C(c1cncnc1)N(CCc1cccc(F)c1)C(=O)CCl,3CL,medium,470,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C(=O)NC1CCC(F)(F)CC1)(c1cnccn1)N(C(=O)CCl)c1ccc(-c2ccns2)cc1,3CL,medium,120,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)n1ccc2cc(C(=O)Oc3cncc(Cl)c3)ccc21,3CL,medium,400,ic50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCN(S(=O)(=O)C2CC2)CC1)C(c1cnccn1)N(C(=O)CCl)c1ccc(-c2cnco2)cc1,3CL,medium,480,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCCNC(=O)c1ccc(-n2sc3ccccc3c2=O)cc1,3CL,medium,910,ic50,WO2021205290A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCC(NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1)C(=O)C(=O)NCc1ccccn1,3CL,medium,450,ic50,WO2021205290A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCCCC1)C(c1cccnc1)N(CCc1cccc(F)c1)C(=O)CCl,3CL,medium,330,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCC(F)(F)CC1)C(c1cncnc1)N(C(=O)CCl)c1ccc(-c2ccno2)cc1,3CL,medium,110,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)CCl)C(C(=O)NC2CCCCC2)c2ccnnc2)cc1,3CL,medium,420,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC(CCF)CCF)[C@H](c1ccnnc1)N(C(=O)CCl)c1ccc(-c2ccns2)cc1,3CL,medium,530,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)C[C@H](NC(=O)[C@H]1CC[C@H](C#N)CC1)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,medium,606,Ki,WO2021188620A1,Over 100 nM
O=c1c2ccccc2[se]n1CCN1CCOCC1,3CL,medium,240,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
Clc1ccc(SSc2nnco2)cc1,3CL,medium,240,Ki,WO2021219089A1,Over 100 nM
O=C(Oc1cncc(Cl)c1)c1cccc([N+](=O)[O-])c1,3CL,medium,684,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)c1cc2cc(O)ccc2[nH]1)C(=O)C[C@@H](C[C@@H]1CCNC1=O)C(=O)c1nc2ccccc2s1,3CL,medium,160,Ki,WO2005113580A1,Over 100 nM
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)C3(C)CCC3)cc12,3CL,medium,348,Ki,WO2021205290A1,Over 100 nM
CC(C)C[C@H](NC(=O)OC1CCN(C(=O)OC(C)(C)C)CC1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(O)S(=O)(=O)O,3CL,medium,300,ic50,WO2021205290A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(N[C@@H](CC1CCCCC1)C(=O)N[C@@H](CC1CCNC1=O)C(O)P(=O)(OCC(F)(F)F)OCC(F)(F)F)OCc1ccccc1,3CL,medium,250,ec50,US20150133368A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)c1cc2cc(Cl)ccc2[nH]1)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,medium,117,Ki,US20150133368A1,Over 100 nM
O=C[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cc2cc(F)ccc2[nH]1,3CL,medium,111,ic50,WO2018042343A2, not Ki or Kd; not used in NCI fingerprint analysis
O=C(N[C@H]1CCOC1)[C@H](c1cncnc1)N(C(=O)CCl)c1ccc(-c2cnco2)cc1,3CL,medium,310,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C#N)C[C@@H]3CCNC3=O)c(C(F)(F)F)c12,3CL,medium,351,Ki,WO2021219089A1,Over 100 nM
CCOC(=O)/C=C/[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)/C=C/c1ccc(OC)cc1OC,3CL,medium,110,ec50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(N[C@@H](Cc1ccc(F)cc1)C(=O)CCl)OCc1ccccc1,3CL,medium,380,Ki,WO2021151265A1,Over 100 nM
CC(C)C[C@H](NC(=O)c1nc2ccccc2s1)C(=O)C[C@@H](C[C@@H]1CCNC1=O)C(=O)c1nc2ccccc2s1,3CL,medium,800,Ki,WO2021219089A1,Over 100 nM
CC(C)(C)OC(=O)NCn1[se]c2ccccc2c1=O,3CL,medium,330,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCC(F)(F)CC1)[C@H](c1cnccn1)N(C(=O)CCl)c1ccc(-c2cncs2)cc1,3CL,medium,270,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(N[C@@H](Cc1c[nH]c2ccccc12)[C@@H](O)[C@H](O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OCc1ccccc1)OCc1ccccc1,3CL,medium,340,Ki,WO2021219089A1,Over 100 nM
O=C[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@@H]1C2CCCC2CN1C(=O)/C=C/c1ccccc1,3CL,medium,525.9,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)CCl)[C@@](C)(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,medium,230,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
C=CCn1sc2ccccc2c1=O,3CL,medium,630,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3ccn(C)n3)cc12,3CL,medium,118,Ki,WO2021205290A1,Over 100 nM
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N(C)C)C(=O)CO)cc12,3CL,medium,190,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)CCl)C(C(=O)NC2CCCCC2)c2cncc(C#N)c2)cc1,3CL,medium,800,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCC1CCC(OC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C=O)C[C@@H]2CCNC2=O)CC1,3CL,medium,250,ec50,CN113181339A, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](CC1CCCCC1)C(=O)NC(C=O)Cc1c[nH]cn1)C(C)C,3CL,medium,340,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Oc1cncc(Cl)c1)c1cc2ccccc2o1,3CL,medium,170,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NCCc1ccccc1)C(c1cnccn1)N(C(=O)CCl)c1ccc(-c2cnco2)cc1,3CL,medium,560,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccccc1C(=O)OCC(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC(C)C)NC(=O)c1cc2c(OC)cccc2[nH]1,3CL,medium,147,Ki,WO2021205290A1,Over 100 nM
O=C(Oc1cncc(Cl)c1)c1cccc2ccccc12,3CL,medium,124,ic50,WO2021205290A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Oc1cncc(Cl)c1)c1ccc(-c2ccccc2[N+](=O)[O-])o1,3CL,medium,208,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)CNS(C)(=O)=O)cc12,3CL,medium,107,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCC(F)(F)CC1)C(c1cncnc1)N(C(=O)CCl)c1ccc(-c2ccncn2)cc1,3CL,medium,450,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCNC(=O)c1ccc(-n2sc3ccccc3c2=O)cc1,3CL,medium,230,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=c1c2ccccc2sn1-c1ccc(Cl)cc1,3CL,medium,390,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)[C@@H](C(=O)N[C@@H](CC(C)(C)C)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O)c1ccc(C(F)(F)F)cc1,3CL,medium,333,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCN(S(=O)(=O)C2CC2)CC1)C(c1cncnc1)N(C(=O)CCl)c1ccc(-c2cnco2)cc1,3CL,medium,720,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC1CCNC1=O)C(O)P(=O)(O)O,3CL,medium,800,ec50,US20150133368A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)c1ccc(CCC(=O)N2CC3CCCC3[C@H]2C(=O)N[C@H](C=O)C[C@@H]2CCNC2=O)cc1,3CL,medium,378.2,ic50,US20150133368A1, not Ki or Kd; not used in NCI fingerprint analysis
O=c1c2ccccc2[se]n1-c1cccc([N+](=O)[O-])c1,3CL,medium,150,ic50,CN113321650A, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncccc1-c1ccc(N(Cc2ccsc2)C(=O)Cn2nnc3ccccc32)cc1,3CL,medium,700,ic50,CN113321650A, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)c1cc2cc(C(F)(F)F)ccc2[nH]1)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,medium,261,Ki,WO2021219089A1,Over 100 nM
CC(C)C[C@H](NC(=O)c1cc2ccc(Cl)cc2[nH]1)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,medium,122,Ki,WO2021219089A1,Over 100 nM
O=C(NC1CCC(F)(F)CC1)C(c1ccnnc1)N(C(=O)CCl)c1ccc(-c2ccno2)cc1,3CL,medium,360,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOCCOCCN(C)C(=O)CC[C@@H](C=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCCCCC(=O)N[C@@H](CC(C)C)C1=NC(CCC(=O)NC)CO1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H]1C[C@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)NC2CCC(F)(F)CC2)c2cnccc2C)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NCc1cc(F)cc(F)c1)C(=O)[C@H](C[C@@H]1CCCNC1=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)c1cc2ccccc2o1,3CL,not active,7600,ic50,WO2021205290A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(NC(=O)C(c2cccnc2)N(C(=O)[C@H]2C[C@@H](OC)CN2C#N)c2ccc(S(F)(F)(F)(F)F)cc2)cn1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
N#Cc1c(-c2ccc(Cl)cc2)nc(SCc2ccc([N+](=O)[O-])cc2)[nH]c1=O,3CL,not active,6100,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2C[C@H](Oc3ccccc3)CN2C#N)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(CC(=O)N[C@@H](CC(C)(C)C)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O)C(F)(F)F,3CL,not active,2230,Ki,WO2021212039A1,Over 100 nM
C=C([C@@H]1CC(C(=O)NC)C/C=C/CCC(CCCCCCC)OC(=O)N[C@@H](CC(C)C)C(=O)N1)N(C)OC,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H]1C[C@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)N(C)CC(=O)NC2CC2)c2cccnc2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN(CC)C(=S)SSC(=S)N(CC)CC,3CL,not active,9350,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C[C@H](Cc1c[nH]cn1)NC[C@@H]1C[C@@H]2CCCC[C@H]2CN1C(=O)c1ccc(Br)cc1,3CL,not active,63000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@H]1C[C@H](C(=O)N(c2ccc(C(C)(C)C)cc2)C(C(=O)NC2CCCCC2)c2cccnc2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)c2cnc[nH]2)C(C(=O)NC2CCCCC2)c2nccnc2C#N)cc1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOP(=O)(OCC)C(O)[C@H](CCC(=O)N1CCOC(c2ccccc2)C1)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,19000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
N#CN1C[C@@H](F)C[C@@H]1C(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)NC1CCC(F)(F)CC1)c1cncc(F)c1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1C(=O)N(Cc2ccc3ccccc3c2)c2ccc(C(=O)N3CCCCC3)cc21,3CL,not active,87760,ic50,WO2021160220A1, not Ki or Kd; not used in NCI fingerprint analysis
CSc1sc(-c2nc(C)cs2)c(C)c1-c1ccnc(SCC(=O)Nc2ccccc2Cl)n1,3CL,not active,12000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@@H]1NC(=O)OC(Cc2ccccc2)CCCCCC(C(=O)N(C)C)C[C@@H](C=O)NC1=O,3CL,not active,185400,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCC1CCCC/C=C/CC(C(=O)N(C)Cc2ccc(OC)cc2OC)C[C@@H](C(O)P(=O)(OCC)OCC)NC(=O)[C@H](CC(C)C)NC1=O,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(N[C@@H](Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)F)OCc1ccccc1,3CL,not active,20000,ic50,CN113181339A, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H]1C[C@H](C(=O)N(c2ccc(C(C)(C)C)cc2F)C(C(=O)NC2CCC(F)(F)CC2)c2cncc(F)c2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2CCCN2C#N)C(C(=O)N2CC(O)C2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCCCC1CCCCCC(C(=O)N(C)C)C[C@@H](C(=O)N(C)OC)NC(=O)[C@H](CC(C)C)NC1=O,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOP(=O)(OCC)C(O)[C@H](CCC(=O)N1CCCCc2ccccc21)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOP(=O)(OCC)C(O)[C@H](CCC(=O)N1CCCC(c2ccccc2)C1)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCCCC1CCCCCCC(C(=O)N(C)C)C[C@@H](C(=O)N(C)OC)NC(=O)[C@H](CC(C)C)NC(=O)O1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)NC(=O)CC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnc2ccccc2n1)C(=O)C(=O)NCc1ccccc1,3CL,not active,4500,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCC(F)(F)CC1)C(c1cncnc1)N(C(=O)C1CO1)c1ccc(-c2ccno2)cc1,3CL,not active,1990,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H]1C[C@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)NCCc2cc(F)cc(F)c2)c2cccnc2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)[C@H](Cc1cccc2ccccc12)NC(=O)OCc1ccccc1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)C(=O)NC(C)C,3CL,not active,5000,ec50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NCc1ccccc1)C(=O)[C@H](C[C@@H]1CCCNC1=O)NC(=O)[C@H](Cc1cccc(F)c1)NC(=O)c1cc2c(Cl)cc(Cl)cc2[nH]1,3CL,not active,6800,ic50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)CF,3CL,not active,100000,ec50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
Nc1ncnc2[nH]c(C(F)(F)F)nc12,3CL,not active,13900,ic50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2CCCN2C#N)C(C(=O)N2CCC(N)CC2)c2cccnc2)cc1,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)c2cnc[nH]2)C(C(=O)NC2CCCCC2)c2ccc(C(F)(F)F)nc2Cl)cc1,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)CNC(C)=O)cc12,3CL,not active,2650,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)c2cnc[nH]2)C(C(=O)NC2CCCCC2)c2ccccn2)cn1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOP(=O)(OCC)C(O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cccc2ccccc12)NC(=O)OCc1ccccc1,3CL,not active,150000,CC50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)/C=C/[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C,3CL,not active,2260,Ki,WO2021205290A1,Over 100 nM
COP(=O)(OC)C(O)[C@H](CC1CCNC1=O)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1,3CL,not active,3500,ec50,US20150133368A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1CC[C@H](C(=O)N(c2ccc(C(C)(C)C)cc2)C(C(=O)NC2CCCCC2)c2cccnc2)N1C#N,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOP(=O)(OCC)[C@H](O)[C@@H]1CC(C(=O)N(C)Cc2ccc(OC)cc2OC)C/C=C/CCC(Cc2ccccc2)OC(=O)N[C@@H](CC(C)C)C(=O)N1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C[C@H](Cc1c[nH]cn1)NC[C@H]1C[C@@H]2CCCC[C@H]2CN1C(=O)c1ccc(-c2ccccc2)cc1,3CL,not active,240000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2CCCN2C#N)C(C(=O)N2CCCC2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2C[C@@H](O)CN2C#N)C(C(=O)NC2CCCCC2)c2cncc(F)c2)cc1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@@H]1NC(=O)OC(Cc2ccccc2)CC/C=C/CC(C(=O)N(C)C)C[C@@H](C(=O)C(=O)NC(C)C)NC1=O,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
N#CN1C[C@H](F)C[C@@H]1C(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)NC1CCC(F)(F)CC1)c1cncc(F)c1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CC[C@H](C(=O)N(c2ccc(C(C)(C)C)cc2)C(C(=O)NC2CCCCC2)c2cccnc2)N1C#N,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCC(F)(F)CC1)C(c1cncc(F)c1)N(C(=O)c1cnc[nH]1)c1ccc(C2CC2)cc1F,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H]1C[C@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)NC2CC3CCC(C2)O3)c2cccnc2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)NCCN(C)C(=O)CC[C@@H](C=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2C[C@@H](O)CN2C#N)C(C(=O)NC2CCCC2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)COC(=O)c1c(Cl)cccc1Cl,3CL,not active,1280,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2CCCN2C#N)C(C(=O)NC2CC2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)NC(=O)C(=O)[C@H](C[C@@H]1CCCNC1=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)c1cc2ccccc2[nH]1,3CL,not active,25300,ic50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NCc1ccccc1)C(=O)[C@H](C[C@@H]1CCCNC1=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)c1cccnn1,3CL,not active,5600,ic50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
N#CN1CCC(F)(F)C1C(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)NC1CCOCC1)c1cncc(F)c1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)O)C(C)C)C(=O)N[C@H](C#N)CCC(N)=O,3CL,not active,39000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)C2NCC[C@H]2F)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(CCc1ccccc1Cl)C(=O)CC[C@@H](C=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
N#CN1C[C@H](O)C[C@@H]1C(=O)N(c1ccc(C2(C(F)(F)F)CC2)cc1)C(C(=O)NC1CCCCC1)c1cccnc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)CN(C)C)cc12,3CL,not active,100000,ec50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)/C=C/[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)c1cc(C)on1)C(C)C,3CL,not active,13200,Ki,WO2021205290A1,Over 100 nM
CCOP(=O)(OCC)C(O)[C@@H]1CC(C(=O)N(C)C)CCCCCC(Cc2ccccc2)OC(=O)N[C@@H](CC(C)C)C(=O)N1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2CSCCN2C#N)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=c1c([C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12,3CL,not active,42700,ic50,WO2021205290A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)C=O)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,50000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
C=C(CC)C(=O)c1ccc(OCC(=O)NC(=O)OC(C)(C)C)c(Cl)c1Cl,3CL,not active,45800,Ki,CN113321650A,Over 100 nM
CC(C)(C)c1ccc(N(C(=O)[C@H]2CCC(C)(C)N2C#N)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)C2CS(=O)(=O)CCN2C#N)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCS(=O)(=O)NCCN(C)C(=O)CC[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1)C(=O)NOC,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1C(=O)N(Cc2cc3ccccc3s2)c2ccc(F)cc21,3CL,not active,4820,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc2cc(CN(CCc3ccccc3C)C(=O)NCc3ccccc3)c(=O)[nH]c2cc1C,3CL,not active,17200,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)C2CC(O)CN2C#N)C(C(=O)NC2CCCCC2)c2cncc3ccccc23)cc1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H]1C[C@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)N2CCC3(COC3)C2)c2cccnc2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@@H]2CCCN2)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1cc2c(cc1O)[C@@]1(C)CCC[C@@](C)(C=O)C1CC2,3CL,not active,163200,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)C[C@H](NC(=O)CN1CCCC1)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,not active,1080,Ki,CN113321650A,Over 100 nM
CC(C)(C)NC(=O)C(c1cccnc1)N(C(=O)c1ncco1)c1ccc(C(C)(C)C)cc1,3CL,not active,47000,ic50,CN113181339A, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)CCNc2cc(N(C(=O)[C@H]3C[C@@](C)(O)CN3C#N)C(C(=O)NC3CCC(F)(F)CC3)c3cncc(F)c3)ccc21,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C(=O)CC[C@@H](C=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1)c1ccccc1,3CL,not active,40300,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)C1=NOC(C)C1)C(C)C)C(=O)N[C@H](C#N)CCC(N)=O,3CL,not active,49000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CCC(=O)N(C)C)C(=O)CF,3CL,not active,2400,ec50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)Cn1[nH]c(=O)c2ccccc2c1=O)C(C)O)C(C)C,3CL,not active,2900,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(-c2cccnc2)cc(F)c1NC(=O)C(c1cncnc1)N(C(=O)CCl)c1ccc(-c2cnco2)cc1,3CL,not active,1390,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)Nc1cnc(SSc2ccccc2[N+](=O)[O-])s1,3CL,not active,1900,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NCc1ccccc1)C(=O)[C@H](C[C@@H]1CCCNC1=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)c1cc2ccccc2o1,3CL,not active,2400,ic50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@](C(=O)NC1CCC(F)(F)CC1)(c1cnccn1)N(C(=O)CCl)c1ccc(-c2ccns2)cc1,3CL,not active,3490,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
C=C(C)[C@@H]1CC[C@]2(C(=O)O)CC[C@]3(C)C(CCC4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]43C)C12,3CL,not active,10000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(N[C@@H](Cc1ccccc1)C(=O)Nc1ccc([N+](=O)[O-])cc1Cl)c1ccc([N+](=O)[O-])cc1,3CL,not active,10000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)C(=O)CC[C@H](NC(=O)CNC(=O)OCc1ccccc1)C(=O)CF,3CL,not active,100000,ec50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C(=O)Nc1ccc(N(C(=O)Cn2nnc3ccccc32)C(C(=O)NCc2ccccc2)c2cccc(F)c2)cc1,3CL,not active,1600,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)c2nccnc2C#N)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,10000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)NC(=O)C(c1cccnc1)N(C(=O)c1cnco1)c1ccc(C(C)(C)C)cc1,3CL,not active,39000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2CCCN2C#N)C(C(=O)NCc2ccccn2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)CCl)[C@@H](C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,1980,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COCCCNC(=O)C(c1cccnc1)N(C(=O)[C@H]1C[C@@H](O)CN1C#N)c1ccc(C(C)(C)C)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2CCCN2C#N)C(C(=O)NC2CCCCC2)c2cncc(F)c2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)C(=O)CC[C@@H](C=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@]1(O)C[C@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)NC2CCOCC2)c2cnccn2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(OC)c2cc(C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)C(=O)NC(C)(C)C)[nH]c2c1,3CL,not active,5800,ic50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
CN1CC(C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)NC2CCOCC2)c2cccnc2)N(C#N)CC1=O,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)NC(=O)C(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cc2ccccc2o1,3CL,not active,15200,ic50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
N#Cc1c(-c2cccc([N+](=O)[O-])c2)nc(SCc2ccc([N+](=O)[O-])cc2)[nH]c1=O,3CL,not active,10600,ic50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
O=c1sn(-c2cccc3ccccc23)c(=O)n1Cc1ccccc1,3CL,not active,1550,ic50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCC(CCN(C(=O)CCl)C(C(=O)NC2CCCCC2)c2cccnc2)CC1,3CL,not active,25000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)c2cnc[nH]2)C(C(=O)NC2CCCCC2)c2cccnc2)c(C#N)n1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1CCN(S(=O)(=O)c2ccc3c(c2)C(=O)C(=O)N3Cc2ccccc2)CC1,3CL,not active,1040,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H](NC(=O)C(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)c1ccc2ccccc2n1)c1ccccc1,3CL,not active,26400,ic50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H]1C[C@H](C(=O)N(c2ccc(C(C)(C)C)cc2)C(C(=O)NC2CCCCC2)c2cccnc2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)COC(=O)c3ccc(Cl)cc3O)cc12,3CL,not active,32000,ec50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2CCCN2C#N)C(C(=O)NCc2ccncc2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@@H]2CCN2)[C@H](C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2CCCN2C#N)C(C(=O)N[C@H]2C[C@@](C)(O)C2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)c2cnc[nH]2)C(C(=O)NC2CCCCC2)c2cncnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C(=O)Nc1ccc(N(Cc2ccn(C)c2)C(=O)Cn2nnc3ccccc32)cc1,3CL,not active,3600,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
N#CN1CC(=O)NCC1C(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)NC1CCC(F)(F)CC1)c1cncc(F)c1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
N#CN1C[C@H](O)C[C@@H]1C(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)NC1CCC(F)(F)CC1)c1cncc(F)c1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)OC(=O)NC1CCN(C(=O)C(c2cccnc2)N(C(=O)[C@H]2CCCN2C#N)c2ccc(C(C)(C)C)cc2)CC1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN(CCc1ccccc1)C(=O)CC[C@@H](C=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
N#CN1C[C@H](O)C[C@@H]1C(=O)N(c1ccc(C2(C(F)(F)F)CC2)cc1)C(C(=O)NC1CCC(F)(F)CC1)c1cncc(F)c1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)NC(=O)N[C@@H](C(=O)N1C[C@@H]2[C@H]([C@@H]1C(=O)NC(CC1CCC1)C(=O)C(N)=O)C2(C)C)C(C)(C)C,3CL,not active,4130,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)NC(=O)C(c1cccnc1)N(C(=O)c1ccc(Cl)o1)c1ccc(C(C)(C)C)cc1,3CL,not active,5200,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2COCCN2C#N)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CC(C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)NC2CCC(F)(F)CC2)c2cncc(F)c2)N(C#N)CC1=O,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC1CCNC1=O)C(=O)C(=O)NC(C)C,3CL,not active,4700,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)OCCN(C)C(=O)CC[C@@H](CO)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C=O)CC1CCCCC1)C(C)C,3CL,not active,62000,ic50,WO2018042343A2, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H]1C[C@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)N2CCN(C(=O)OC(C)(C)C)CC2)c2cccnc2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCCCC1)C(=O)[C@H](C[C@@H]1CCCNC1=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1nc2ccccc2[nH]1,3CL,not active,5600,ic50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2Cc3ccccc3CN2C#N)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@]1(O)C[C@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)NC2CCC(F)(F)CC2)c2cncc(F)c2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
C=C(F)C(=O)N(c1ccc(-c2cncs2)cc1)C(C(=O)NC1CCC(F)(F)CC1)c1cncnc1,3CL,not active,8360,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(=O)N[C@@H](CCC(=O)N1CCOCC1)C(=O)C(F)(F)F,3CL,not active,21000,Ki,WO2021219089A1,Over 100 nM
O=C(N[C@@H](Cc1ccccc1)C(=O)Nc1ccc([N+](=O)[O-])cc1)c1ccccc1,3CL,not active,10000,ic50,CN113181339A, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ncoc1-c1ccc(N(C(=O)CCl)C(C(=O)NC2CCCCC2)c2cncnc2)cc1,3CL,not active,25000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2CCCN2C#N)C(C(=O)NCC2COC2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
N#CN1C[C@H](O)C[C@@H]1C(=O)N(c1ccc2c(c1)NCCC2)C(C(=O)NC1CCCCC1)c1cccnc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)C2CCC(F)(F)CN2C#N)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC1CCCCC1)c1cccnc1,3CL,not active,50000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(OCc1ccccc1COC(=O)c1cc(B(O)O)cc([N+](=O)[O-])c1)c1cc(B(O)O)cc([N+](=O)[O-])c1,3CL,not active,6000,Ki,WO2021205290A1,Over 100 nM
CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)OCc1ccccc1)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)C(F)(F)F,3CL,not active,10000,ic50,WO2021205290A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@H](NC(=O)/C=C/c1ccccc1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)C(=O)NCc1ccccc1,3CL,not active,50000,ic50,WO2021205290A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(O)c1cc(O)cc(B(O)O)c1,3CL,not active,3500,Ki,WO2018042343A2,Over 100 nM
CC(C)(C)c1ccc(N(C(=O)[C@H]2CCCN2C#N)C(C(=O)N2CCOCC2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(CN(C)C(=O)C(=O)[C@H](C[C@@H]2CCCNC2=O)NC(=O)[C@H](CC2CCCCC2)NC(=O)c2cc3ccccc3o2)cc1,3CL,not active,4800,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(Cl)C(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC1CCCCC1)c1cccnc1,3CL,not active,25000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)NC(=O)C(c1ccncc1)N(C(=O)c1ccco1)c1ccc(C(C)(C)C)cc1,3CL,not active,45000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
N#CN1C[C@H](O)C[C@@H]1C(=O)N(c1ccc(C2CC2)c(F)c1)C(C(=O)NC1CCCCC1)c1cccnc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
Nc1nc2nc3nc(N)sc3cc2s1,3CL,not active,2600,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)=CC[C@@H](O)C1=CC(=O)c2c(O)ccc(O)c2C1=O,3CL,not active,15750,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@@H](C=O)NC(=O)[C@@H](NS(=O)(=O)c1ccc(F)cc1)C(C)C,3CL,not active,20000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCCCC1)C(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cc2ccccc2o1,3CL,not active,24100,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2C[C@H](O)CN2C#N)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)OCc1ccccc1)C(C)C)C(=O)N[C@H](C#N)CCC(N)=O,3CL,not active,4600,ic50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C=O)Cc1cccs1)C(C)C,3CL,not active,48000,ic50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)/C=C/[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](Cc1ccc(F)cc1)NC(=O)[C@@H](NC(=O)c1cc(C)on1)C(C)C,3CL,not active,10000,Ki,CN113197895A,Over 100 nM
CCOP(=O)(OCC)C(O)[C@H](CCC(=O)N(C)CC(C)c1ccccc1)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CNC(=O)c1cc(C)c(NC(=O)C(c2cncnc2)N(C(=O)CCl)c2ccc(-c3cnco3)cc2)c(Cl)c1,3CL,not active,1090,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)F,3CL,not active,15000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCC(F)(F)CC1)[C@H](c1cncnc1)N(C(=O)[C@@H](F)Cl)c1ccc(-c2cncs2)cc1,3CL,not active,1700,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1CN(C#N)[C@H]1C(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)NC1CCC(F)(F)CC1)c1cncc(F)c1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1CCCCC1C(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)NC1CCC(F)(F)CC1)c1cncc(F)c1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NCc1ccccc1)C(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](Cc1cccc(F)c1)NC(=O)c1ccc2ccccc2n1,3CL,not active,8500,ic50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2C[C@@H](O)CN2C#N)C(C(=O)NC2CCC(F)(F)CC2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CCC(=O)N(C)C)C(=O)CF,3CL,not active,5300,ec50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)NC(=O)N[C@H](C(=O)N1C[C@H]2[C@@H]([C@H]1C(=O)NC(CC1CCC1)C(=O)C(N)=O)C2(C)C)C(C)(C)C,3CL,not active,1180,Ki,WO2021219089A1,Over 100 nM
CN(CCc1ccc(Cl)cc1)C(=O)CC[C@@H](C=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,31000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
N#CC1(C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)NC2CCC(F)(F)CC2)c2cncc(F)c2)CC1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H]1C[C@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)N[C@H]2C[C@@](C)(O)C2)c2cccnc2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@@H]2CCN2C#N)[C@@H](C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H]1C[C@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)N2CCCC3(COC3)C2)c2cccnc2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)OC(C)(C)C)C(C)C)C(=O)N[C@H](C#N)CCC(N)=O,3CL,not active,49000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](/C=C/C(=O)OCc2ccccc2)C[C@@H]2CCNC2=O)C(C)C)no1,3CL,not active,2700,ic50,WO2021151265A1, not Ki or Kd; not used in NCI fingerprint analysis
CON(C)C(=O)[C@H](CCC(=O)N1CCCC(c2ccccc2)C1)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,185400,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
N#CC1(Nc2ccc(S(F)(F)(F)(F)F)cc2)CCCc2ccncc21,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1=C(C(=O)OCCc2ccccc2)C(c2ccccc2[N+](=O)[O-])C2C(=O)CCCC2N1,3CL,not active,2500,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cncc(C(C(=O)NC2CCCCC2)N(C(=O)[C@H]2C[C@@H](O)CN2C#N)c2ccc(C(C)(C)C)cc2)c1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2[C@H](F)CCN2C#N)C(C(=O)NC2CCC(F)(F)CC2)c2cncc(F)c2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)/C=C/[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@@H](CC(=O)[C@@H](NC(=O)c1cc(C)on1)C(C)C)Cc1ccc(F)cc1,3CL,not active,20000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H](NC(=O)[C@H](N)CCC(=O)NCC(=O)C(F)(F)F)C(=O)O,3CL,not active,50000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(O)c1ccc(/C=C2\C(=O)N(c3ccc([N+](=O)[O-])cc3)NC2c2ccccc2)cc1,3CL,not active,8400,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
[2H]C(C(=O)NC1CCOCC1)(c1cnccn1)N(C(=O)[C@H]1C[C@@](C)(O)CN1C#N)c1ccc(S(F)(F)(F)(F)F)cc1,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c[nH]c2cc(N(C(=O)[C@H]3C[C@@H](O)CN3C#N)C(C(=O)NC3CCC(F)(F)CC3)c3cncc(F)c3)ccc12,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCCNC(=O)n1cc(F)c(=O)[nH]c1=O,3CL,not active,1820,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCC(F)(F)CC1)[C@H](c1cncnc1)N(CCc1cccc(F)c1)C(=O)C1CO1,3CL,not active,22560,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C(=O)C(c1cccnc1)N(C(=O)[C@H]1CCCN1C#N)c1ccc(C(C)(C)C)cc1)C1CCCCC1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CSc1sc(-c2nc(C)cs2)c(C)c1-c1ccnc(SCC(=O)Nc2ccc(Cl)cc2)n1,3CL,not active,11000,ic50,CN113321650A, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Oc1c(Cl)cc(Cl)cc1[N+](=O)[O-])c1cc(B(O)O)cc([N+](=O)[O-])c1,3CL,not active,6900,Ki,CN113321650A,Over 100 nM
NC(=O)c1nc(C2CC2)ccc1N(C(=O)c1cnc[nH]1)[C@H](C(=O)NC1CCCCC1)c1cccnc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CCC(=O)N(C)C)C(=O)CF,3CL,not active,100000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](NC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)C(=O)NCC(=O)C(F)(F)F,3CL,not active,40000,ic50,WO2021151265A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(/C=C/c1ccccc1)N[C@H](COC(=O)c1ccccc1)C(=O)NC1CCCCC1,3CL,not active,30000,ic50,CN113321650A, not Ki or Kd; not used in NCI fingerprint analysis
Cc1oc2ccc(N(C(=O)CCl)C(C(=O)NC3CCCCC3)c3cccnc3)cc2c1C,3CL,not active,25000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)/C=C/[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@@H](CC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)OC(C)(C)C)C(C)C)Cc1ccccc1,3CL,not active,15000,ic50,CN113181339A, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CCC(=O)N(C)C)C(=O)CF,3CL,not active,6600,ec50,WO2021151265A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1C(=O)N(Cc2ccc3ccccc3c2)c2ccc(C(=O)N3CCCC3)cc21,3CL,not active,70350,ic50,WO2021151265A1, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H]1C[C@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)N2CCN(C)C(=O)C2)c2cccnc2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)CNc2cc(N(C(=O)[C@H]3C[C@@](C)(O)CN3C#N)C(C(=O)NC3CCC(F)(F)CC3)c3cncc(F)c3)ccc21,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCCSc1ccccc1CNC(=O)/C=C/c1ccccc1,3CL,not active,4920,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)N/C(=C\c2ccc(-c3cccc([N+](=O)[O-])c3)o2)C(=O)NCCCN(C)C)cc1,3CL,not active,9110,Ki,WO2021212039A1,Over 100 nM
CC(C)(C)c1ccc(N(C(=O)[C@H]2C[C@@H](O)CN2C#N)C(C(=O)NC2CCCCC2)c2cncc(Cl)c2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(/C=C/C(=O)N[C@H](COC(=O)c2ccccc2)C(=O)NC2CCCCC2)cc(OC)c1OC,3CL,not active,65000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCCCC1CCCCCCCC(C(=O)N(C)C)C[C@@H](C=O)NC(=O)[C@H](CC(C)C)NC1=O,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
COCC(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC(C)(C)C)NC(=O)[C@H]1CCCO1,3CL,not active,1080,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)CC[C@H](NC(=O)OCc1ccccc1)C(=O)NC(CCC(=O)N(C)C)C(=O)CC(F)F,3CL,not active,2500,ec50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2C[C@@H](Oc3ccccc3)CN2C#N)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)OCCC12CC3CC(CC(C3)C1)C2)C(=O)N[C@H](C=O)C[C@@H]1CCNC1=O,3CL,not active,100000,CC50,WO2021205290A1, not Ki or Kd; not used in NCI fingerprint analysis
N#CN1CC[C@@H](F)[C@@H]1C(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)NC1CCC(F)(F)CC1)c1cncc(F)c1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)NCCN(C)C(=O)CC[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1)C(O)P(=O)(OCC)OCC,3CL,not active,46000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(SSc2nccs2)cc1,3CL,not active,1300,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)/C=C/[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)/C=C/c1ccc([N+](=O)[O-])cc1,3CL,not active,2480,Ki,WO2018042343A2,Over 100 nM
O=C(Nc1ccc([N+](=O)[O-])cc1Cl)c1cc(Cl)ccc1O,3CL,not active,50000,ic50,WO2018042343A2, not Ki or Kd; not used in NCI fingerprint analysis
CCC(C)SSc1ncc[nH]1,3CL,not active,21390,ic50,WO2018042343A2, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCCCCC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CO)CCC(=O)NC,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(CN(C)C(=O)CC[C@@H](C=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1)c1ccccc1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NCc1ccccc1)C(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)c1cc2ccccc2o1,3CL,not active,4891,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H]1C[C@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)NC2CCC(F)(F)CC2)c2cccnc2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)c2nccnc2C(N)=O)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)c2c[nH]cn2)C(C(=O)NC2CCCCC2)c2cccnc2C#N)cc1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)CCl)[C@H](C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,2150,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
N#CCC(=O)N(c1ccc(-c2cncs2)cc1)[C@H](C(=O)NC1CCC(F)(F)CC1)c1cncnc1,3CL,not active,23200,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)C2CCCN2C#N)C(C(=O)NC2CCC(F)(F)CC2)c2cccnc2)cc1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCCCC1CCCC/C=C/CC2CC(NC(=O)[C@H](CC(C)C)NC1=O)C(O)N(C)C2=O,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
C=C(CC)C(=O)c1ccc(OCC(=O)NC(C)(C)C)c(Cl)c1Cl,3CL,not active,35300,Ki,WO2021191827A1,Over 100 nM
CC1(C(=O)N(c2ccc(C(C)(C)C)cc2)C(C(=O)NC2CCCCC2)c2cccnc2)CNC1,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)C2CO2)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,1440,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)C(F)(F)F,3CL,not active,15000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)OC(=O)N[C@@H](CCC(=O)NCC(=O)C(F)(F)F)C(=O)OC(C)(C)C,3CL,not active,40000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(S(=O)(=O)Nc2ccccc2/N=C/c2cc([N+](=O)[O-])ccc2O)cc1,3CL,not active,98700,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1C[C@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)NC2CCOCC2)c2cccnc2)N(C#N)CC1=O,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)OCC12CC3CC(CC(O)(C3)C1)C2)C(=O)N[C@H](C=O)C[C@@H]1CCNC1=O,3CL,not active,100000,CC50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(-c2cc(=O)c3c(O)cc(O)cc3o2)cc1-c1c(O)cc(O)c2c(=O)cc(-c3ccc(O)cc3)oc12,3CL,not active,72300,ic50,WO2021151265A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1cnc(C(=O)N(c2ccc(C(C)(C)C)cc2)C(C(=O)NC(C)(C)C)c2cccnc2)c1,3CL,not active,75000,ic50,WO2021151265A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(C)=O)cc12,3CL,not active,2300,ic50,WO2021151265A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(/C=C/c1ccccc1)N[C@@H](Cc1ccc(F)cc1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)C(=O)NCc1ccccc1,3CL,not active,50000,ic50,WO2021151265A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(c1ccc(-c2ccc(Cl)cc2)o1)C(F)c1cncc(Br)c1,3CL,not active,28000,ic50,WO2021151265A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCCCC1)C(c1cccnc1)N(Cc1ccc(F)cc1)C(=O)CCl,3CL,not active,16330,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCCCC1CC/C=C\CC(C(=O)NC)C[C@@H](CO)NC(=O)[C@H](CC(C)C)NC1=O,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
N#CN1CC[C@H]2C[C@]21C(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)NC1CCC(F)(F)CC1)c1cncc(F)c1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](NC(=O)C(c1cnccc1C(F)(F)F)N(C(=O)[C@H]1C[C@@](C)(O)CN1C#N)c1ccc(-c2ccccc2)cc1)c1ccccc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOP(=O)(OCC)C(O)[C@@H]1CC2(C/C=C/CCCC(Cc3ccccc3)C(=O)N[C@@H](CC(C)C)C(=O)N1)CCNC2=O,3CL,not active,46500,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NCc1ccccc1)C(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](Cc1ccc(F)cc1)NC(=O)c1ccc2ccccc2n1,3CL,not active,6700,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
N#C[C@H]1C[C@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)NC2CCC(F)(F)CC2)c2cncc(F)c2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(O)c2c(=O)cc(-c3ccc(OC)c(-c4c(O)cc(O)c5c(=O)cc(-c6ccc(O)cc6)oc45)c3)oc2c1,3CL,not active,32700,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
Clc1ccc(-c2c(-n3ccnc3)c(-c3ccc(Br)cc3)nn2-c2ccc(Cl)c(Cl)c2)cc1,3CL,not active,2500,ic50,WO2018042343A2, not Ki or Kd; not used in NCI fingerprint analysis
C=CS(=O)(=O)N(c1ccc(C(C)(C)C)cc1)[C@H](C(=O)NC1CCCCC1)c1cccnc1,3CL,not active,50000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Nc1ccc(N(Cc2ccsc2)C(=O)Cn2nnc3ccccc32)cc1)C1CC1,3CL,not active,4110,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1cc2c(cc1O)[C@@]1(C)CCC(O)C(C)(C)C1CC2,3CL,not active,49600,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)C(F)(F)F)OCc1ccccc1,3CL,not active,20000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COP(=O)(OC)C(O)[C@H](CC1CCNC1=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1ccccc1,3CL,not active,2800,ec50,US20150133368A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)Cn1[nH]c(=O)c2ccccc2c1=O)C(C)OCc1ccccc1)C(C)C,3CL,not active,2700,ic50,US20150133368A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1,3CL,not active,150000,CC50,US20150133368A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)c2cnc[nH]2)C(C(=O)NC2CCCCC2)c2cncnc2C#N)cc1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)c2nsnc2C#N)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,30000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c[nH]c2cc(N(C(=O)[C@H]3C[C@@H](O)CN3C#N)C(C(=O)NC3CCCCC3)c3cccnc3)ccc12,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCC(F)(F)CC1)[C@@H](c1cncnc1)N(CCc1cccc(F)c1)C(=O)C1CO1,3CL,not active,2220,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)NC(C)C(=O)C(F)(F)F,3CL,not active,40000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)OC(=O)N1CC(C(=O)N(c2ccc(C(C)(C)C)cc2)C(C(=O)NC2CCCCC2)c2cccnc2)C1,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)NC(=O)C(c1cccnc1)N(C(=O)[C@H]1CCCN1C#N)c1ccc(C(C)(C)C)cc1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
COCCNC(=O)C(c1cccnc1)N(C(=O)[C@H]1C[C@@H](O)CN1C#N)c1ccc(C(C)(C)C)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CON(C)C(=O)[C@@H]1CC(C(=O)N(C)C)CCCCCC(Cc2ccccc2)OC(=O)N[C@@H](CC(C)C)C(=O)N1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1OC[C@H](Cc2ccc3c(c2)OCO3)/C1=C\c1ccc2c(c1)OCO2,3CL,not active,25000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)NC(=O)[C@@H](c1cccnc1)N(C(=O)c1ccco1)c1ccc(C(C)(C)C)cc1,3CL,not active,1500,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H]1C[C@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)N2CCNCC2)c2cccnc2)N(C#N)C1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2CCCN2C#N)C(C(=O)N2CC[C@H](O)C2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCCCC1)C(c1cccnc1)N(CCc1ccc(F)cc1)C(=O)CCl,3CL,not active,1080,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCC(F)(F)CC1)C(c1cncnc1)N(CCc1cccc(F)c1)C(=O)C1CO1,3CL,not active,6980,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C#N)C(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)NC1CCC(F)(F)CC1)c1cncc(F)c1,3CL,not active,10000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(Cc1ccccc1)C(=O)CC[C@@H](C=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H]1C[C@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)NC2C[C@H](C)O[C@H](C)C2)c2cccnc2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2C[C@@H](O)CN2)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)NC(=O)C(c1cccnc1)N(C(=O)[C@H]1C[C@@H](O)CN1C#N)c1ccc(C(C)(C)C)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)CN(C)C(=O)CC[C@@H](C=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,136900,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)OCCN(C)C(=O)CC[C@@H](C=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(C(=O)C(c2cccnc2)N(C(=O)[C@H]2CCCN2C#N)c2ccc(C(C)(C)C)cc2)CC1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](NC(=O)C(c1cncc(F)c1)N(C(=O)[C@H]1C[C@@](C)(O)CN1C#N)c1ccc(S(F)(F)(F)(F)F)cc1)c1ccccc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)OCCN(C)C(=O)CC[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1)C(=O)N(C)OC,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Nc1ccc(N(C(=O)Cn2nnc3ccccc32)C(C(=O)NCc2ccccc2)c2ccsc2)cc1)C1CC1,3CL,not active,2000,ic50,CN113181339A, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)NC(=O)C(c1ccnnc1)N(C(=O)c1ccco1)c1ccc(C(C)(C)C)cc1,3CL,not active,10000,ic50,CN113181339A, not Ki or Kd; not used in NCI fingerprint analysis
N#CN1C[C@H]2C[C@H]2[C@@H]1C(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)NC1CCC(F)(F)CC1)c1cncc(F)c1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cc(F)cc(F)c1NC(=O)C(c1cncnc1)N(C(=O)CCl)c1ccc(-c2cnco2)cc1,3CL,not active,1060,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CCC(C)c1ccc(N(C(=O)c2ccco2)C(C(=O)NC2CCCC2)c2cccnc2)cc1,3CL,not active,2200,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C([O-])c1ccc(/N=C/c2c(O)ccc3c2C2CCCCC2O3)cc1,3CL,not active,23000,ec50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2[C@H](F)CCN2C#N)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)OCC1CC2C=CC1C2)C(=O)N[C@H](C=O)C[C@@H]1CCNC1=O,3CL,not active,100000,CC50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
N#CN1C[C@H](O)C[C@@H]1C(=O)N(c1ccc(C2CC2)cc1)C(C(=O)NC1CCCCC1)c1cccnc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H]1C[C@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)NC2CCC(F)(F)CC2)c2cnccc2C#N)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCCCC1)C(c1cccnc1)N(Cc1ccccc1C(F)(F)F)C(=O)CCl,3CL,not active,4970,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)C[C@H](NC(=O)C1CCCCC1)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,not active,37000,ec50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCCCC1CC/C=C\CC(C(=O)N(C)C)C[C@@H](C=O)NC(=O)[C@H](CC(C)C)NC1=O,3CL,not active,105300,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H]1C[C@H](C(=O)N(c2ccc(C(C)(C)C)cc2)C(C)(C(=O)NC2CCC(F)(F)CC2)c2cnccn2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2C[C@@H](O)CN2C#N)C(C(=O)NC2CCCCC2)c2cncc3ccccc23)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1c(C(=O)N[C@@H](CC2CCCCC2)C(=O)N[C@@H](C[C@@H]2CCCNC2=O)C(=O)C(=O)NC(C)(C)C)cc2ccccc21,3CL,not active,15200,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(/C=C/c1ccccc1)N[C@H](C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)C(=O)NCc1ccccc1)C1CC1,3CL,not active,30000,ic50,WO2021205290A1, not Ki or Kd; not used in NCI fingerprint analysis
N#Cc1ccc(N2NC(c3ccccc3)/C(=C/c3ccc(C(=O)O)cc3)C2=O)cc1,3CL,not active,5500,ic50,WO2021205290A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)/C=C/[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)OC(C)(C)C)C(C)C,3CL,not active,100000,ic50,WO2021205290A1, not Ki or Kd; not used in NCI fingerprint analysis
N#CN1C[C@H](O)C[C@@H]1C(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)NC1CCCCC1)c1cccnc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
[2H]C([2H])(OC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C=O)C[C@@H]1CCNC1=O)C1CC2CCCC(C2)C1,3CL,not active,100000,CC50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(CCc1ccccc1)C(=O)CC[C@@H](CO)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,14700,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2CCCN2C#N)C(C(=O)N2CCNC(=O)C2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)c2scnc2Cl)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
N#CN1C[C@@H]2CC[C@@H]2[C@@H]1C(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)NC1CCC(F)(F)CC1)c1cncc(F)c1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)CCl)C(C(=O)NC2CCCCC2)c2ccc(C#N)nc2)cc1,3CL,not active,25000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)C(=O)CNC(=O)C(c1cccnc1)N(C(=O)[C@H]1CCCN1C#N)c1ccc(C(C)(C)C)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCC(C)(C)NC(=O)C(c1ccn(C)c1)N(C(=O)Cn1nnc2ccccc21)c1ccc(NC(C)=O)cc1,3CL,not active,6200,ic50,WO2021205290A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N(C)C)C(=O)Cn1[nH]c(=O)c2c([N+](=O)[O-])cccc2c1=O)C(C)Cc1ccccc1)C(C)C,3CL,not active,70000,ic50,WO2021205290A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1noc(C)c1CN1C(=O)C(=O)c2cc(C#N)ccc21,3CL,not active,7200,ic50,WO2021205290A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(O)C[C@H](C(=O)N(c2ccc(C(C)(C)C)cc2)C(C(=O)NC2CCCCC2)c2cccnc2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1C(=O)CCC(NC(=O)[C@H](CC2CCCCC2)NC(=O)OCc2cccc(Cl)c2)C1C#N,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CCN(CCc1ccccc1)C(=O)CC[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1)C(=O)N(C)OC,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C=O)CCC(=O)N(C)C)C(C)C,3CL,not active,37000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccccc1CCN(C(=O)CCl)C(C(=O)NC1CCCCC1)c1cccnc1,3CL,not active,2630,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H]1C[C@H](C(=O)N(c2ccc(C(C)(C)C)cc2)C(C(=O)NC2CCOCC2)c2cccnc2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOP(=O)(OCC)C(O)[C@H](CCC(=O)N(C)CCNS(=O)(=O)CC)NC(=O)[C@H](CC1CCCCC1)NC(=O)NCc1cccc(Cl)c1,3CL,not active,2300,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1cc2c(cc1O)[C@@]1(C)CCC[C@@](C)(CO)C1CC2,3CL,not active,128900,ic50,CN113181339A, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCCCCC(=O)N[C@@H](CC(C)C)C(=O)NC1(C)CCC(=O)N(C)C1(O)C(=O)NC(C)C,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc2nc(-c3ccc(N)cc3)sc2c1S(=O)(=O)O,3CL,not active,4300,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCC(F)(F)CC1)C(c1cncc(F)c1)N(C(=O)c1cnc[nH]1)c1ccc(S(F)(F)(F)(F)F)cc1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2C[C@@H](O)CN2C#N)C(C(=O)NCc2cccnc2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2CCCN2C#N)C(C(=O)NC2CCC(F)(F)CC2)c2cccnc2)cc1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)Oc1ccc(N(C(=O)c2ccco2)C(C(=O)NC(C)(C)C)c2cccnc2)cc1,3CL,not active,28100,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NCc1ccccc1)C(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)c1cc2ccccc2s1,3CL,not active,12500,ic50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C#N)c1ccc(N(C(=O)[C@H]2C[C@@H](O)CN2C#N)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2C[C@@H](O)CN2C#N)C(C(=O)Nc2c(Cl)cccc2Cl)c2cccnc2)cc1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCC(=O)Nc1ccc(N(C(=O)Cn2nnc3ccccc32)C(C(=O)NC(C)(C)C)c2ccn(C)c2)cc1,3CL,not active,6900,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)/C=C/[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@@H](CC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)OC(C)(C)C)C(C)C)CC(C)C,3CL,not active,10000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C[C@H](Cc1c[nH]cn1)NCC1CC2CCCCC2CN1C(=O)c1ccc(F)cc1,3CL,not active,57000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)c2cnc[nH]2)C(C(=O)NC2CCCCC2)c2cccnc2Br)cc1,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2C[C@H](O)CN2)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H]1C[C@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)NCC(C)(C)OC)c2cccnc2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)Cn1[nH]c(=O)c2c([N+](=O)[O-])cccc2c1=O)C(C)O)C(C)C,3CL,not active,3400,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)NC(=O)C(c1cccnc1)N(C(=O)CCl)c1ccc(C(C)(C)C)cc1,3CL,not active,1280,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)C(F)(F)F,3CL,not active,116000,Ki,WO2021219089A1,Over 100 nM
CCOc1ccc2oc(C(=O)N[C@@H](CC3CCCCC3)C(=O)N[C@@H](C[C@@H]3CCCNC3=O)C(=O)C(=O)NCc3ccccc3)cc2c1,3CL,not active,9500,ic50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
N#CN1C[C@H](O)C[C@@H]1C(=O)N(c1ccc(C(F)(C(F)(F)F)C(F)(F)F)cc1)C(C(=O)NC1CCCCC1)c1cccnc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccccc1CCN(C(=O)CCl)C(C(=O)NC1CCCCC1)c1cccnc1,3CL,not active,4340,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCC(F)(F)CC1)C(c1cncnc1)N(C(=O)CCl)c1ccc(-c2cnc[nH]2)cc1,3CL,not active,1180,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1CCC(C(=O)N(c2ccc(C(C)(C)C)cc2)C(C(=O)NC2CCCCC2)c2cccnc2)N1C(=O)OC(C)(C)C,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2CCCN2C#N)C(C(=O)N2CCNCC2)c2cccnc2)cc1,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
N#CN1C[C@@H]2C[C@@H]2[C@@H]1C(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)NC1CCC(F)(F)CC1)c1cncc(F)c1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2Cc3ccccc3CN2)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,30000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
N#CN1CCC[C@@H]1C(=O)N(c1ccc(C2CC2)cc1)C(C(=O)NC1CCCCC1)c1cccnc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc(C(C(=O)NC(C)(C)C)N(C(=O)Cn2nnc3ccccc32)c2ccc(NC(=O)C3CCC3)cc2)c1,3CL,not active,3800,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=c1c(O[C@@H]2OC[C@@H](O)[C@@H](O)[C@@H]2O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12,3CL,not active,31620,ic50,WO2021151265A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1noc(NC(=O)c2ccc(-c3cc(C(F)(F)F)nn3C)s2)c1[N+](=O)[O-],3CL,not active,5000,ic50,WO2021151265A1, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)COC(=O)[C@H](C)NP(=O)(CC[C@H]1O[C@@](C#N)(c2ccc3c(N)ncnn23)[C@H](O)[C@@H]1O)Oc1ccccc1,3CL,not active,7860,ec50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1C(=O)N(Cc2ccccc2)c2ccc(C(=O)N3CCCC3)cc21,3CL,not active,22930,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(S(=O)(=O)C(C)NC(=O)C(c2cccnc2)N(C(=O)CCl)c2ccc(C(C)(C)C)cc2)cc1,3CL,not active,12720,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(CSc1nccc(-c2cc(-c3ccccc3)no2)n1)Nc1ccc(Cl)cc1,3CL,not active,15000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOCCN(C)C(=O)CC[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1)C(O)P(=O)(OCC)OCC,3CL,not active,5400,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)C2N(C#N)CC2(C)C)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,2000,CC50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)OC(=O)N1CCC[C@@H]1C(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC1CCCCC1)c1cccnc1,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2CCCN2C#N)C(C(=O)NC2CCCCC2)c2cncc3ccccc23)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)[C@H](C(=O)N[C@@H](CC(C)(C)C)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O)c1ccccc1,3CL,not active,9370,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
C=C(CC)C(=O)c1ccc(OCC(=O)NC(=O)OC(C)(C)C(N)=O)c(Cl)c1Cl,3CL,not active,35300,Ki,WO2021212039A1,Over 100 nM
O=C[C@H](CCC(=O)N1CCCC(c2ccccc2)C1)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,16700,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOP(=O)(OCC)C(O)[C@H](CC(C)C(=O)N(C)CCc1ccccc1)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)c1nccs1,3CL,not active,2200,Ki,WO2021188620A1,Over 100 nM
CCNC(=O)NCCN(C)C(=O)CC[C@@H](CO)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H]1C[C@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)NC2CCC(F)(F)CC2)c2cnccc2C(F)(F)F)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2C[C@@](C)(O)CN2C#N)C(C(=O)NC2CCC(F)(F)CC2)c2cnccn2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](NC(=O)C(c1cnccc1C(F)(F)F)N(C(=O)[C@H]1C[C@@](C)(O)CN1C#N)c1ccc(S(F)(F)(F)(F)F)cc1)c1ccccc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C[C@H](Cc1c[nH]cn1)NC[C@@H]1C[C@H]2CCCC[C@@H]2CN1C(=O)c1ccc(-c2ccccc2)cc1,3CL,not active,108000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](C)C(=O)C(F)(F)F,3CL,not active,40000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1C(=O)C(=O)c2cc(C(=O)N3CCOCC3)ccc21,3CL,not active,36420,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)OCC12CC3CC(CC(C3)C1)C2)C(=O)N[C@H](C=O)C[C@@H]1CCNC1=O,3CL,not active,100000,CC50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@@H]1NC(=O)C(Cc2ccccc2)CCCCCCCC2CC(NC1=O)C(O)N(C)C2=O,3CL,not active,188340,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
C#CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC1CCCCC1)c1cccnc1,3CL,not active,6280,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(C#N)C(C(=O)N(c2ccc(C(C)(C)C)cc2)C(C(=O)NC2CCCCC2)c2cccnc2)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(C(=O)N/C(=C\c2ccc(-c3ccccc3[N+](=O)[O-])o2)C(=O)NCCCN(C)C)cc1,3CL,not active,9930,Ki,WO2021212039A1,Over 100 nM
CC(C)(C)c1ccc(N(C(=O)[C@H]2CCCN2C#N)C(C(=O)N2CC(=O)C2)c2cccnc2)cc1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](NC(=O)C(c1cnccn1)N(C(=O)c1ccco1)c1ccc(-c2ccccc2)cc1)c1ccccc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(OCc1cccc(B(O)O)c1)c1cc(B(O)O)cc([N+](=O)[O-])c1,3CL,not active,4500,Ki,WO2021212039A1,Over 100 nM
C[C@@H]1C[C@H](C(=O)N(c2ccc(C(C)(C)C)cc2)C(C(=O)NC2CCCCC2)c2cccnc2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1sc(C(F)(F)F)nc1C(=O)N[C@@H](CC(C)(C)C)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,not active,4090,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)/C=C/[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC=C(C)C)CC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)OC(C)(C)C)C(C)C,3CL,not active,80000,ic50,WO2021205290A1, not Ki or Kd; not used in NCI fingerprint analysis
[2H]C([2H])(OC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C=O)C[C@@H]1CCNC1=O)C1CC2C=CCC(C2)C1,3CL,not active,100000,CC50,WO2018042343A2, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H]1O[C@@H](Oc2c(-c3ccc(O)c(O)c3)oc3cc(O)cc(O)c3c2=O)[C@H](O)[C@@H](O)[C@H]1O,3CL,not active,24140,ic50,WO2018042343A2, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N(C)C)C(=O)Cn1[nH]c(=O)c2ccccc2c1=O)C(C)O)C(C)C,3CL,not active,28000,ic50,WO2021151265A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(NC(=O)C(c2cccnc2)N(C(=O)[C@H]2CCCN2C#N)c2ccc(C(C)(C)C)cc2)cn1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2C[C@@H](O)CN2C#N)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)OC(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)C(=O)NCc1ccccc1,3CL,not active,50000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOP(=O)(OCC)C(O)[C@H](CCC(=O)N(C)CCc1ccncc1)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)NC(=O)C(c1cnccn1)N(C(=O)c1ccco1)c1ccc(C(C)(C)C)cc1,3CL,not active,5500,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)OCC1CC2CCC1C2)C(=O)N[C@H](C=O)C[C@@H]1CCNC1=O,3CL,not active,100000,CC50,CN113321650A, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)/C=C/[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)/C=C/c1ccc(-c2ccccc2)cc1,3CL,not active,6440,Ki,CN113321650A,Over 100 nM
O=C1NN(c2ccc(Cl)c(Cl)c2)C(=O)/C1=C\c1ccc(-c2ccc(Br)cc2C(=O)O)o1,3CL,not active,9190,ic50,CN113321650A, not Ki or Kd; not used in NCI fingerprint analysis
Cc1nnsc1C(C(=O)NC1CCCCC1)N(C(=O)c1cnc[nH]1)c1ccc(C(C)(C)C)cc1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2c3ccccc3CN2C#N)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2C[C@@H](O)CN2C#N)C(C(=O)NC2CCOCC2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)NC(=O)C(=O)[C@H](C[C@@H]1CCCNC1=O)NC(=O)[C@H](Cc1cccc(F)c1)NC(=O)c1cc2c(Cl)cc(Cl)cc2[nH]1,3CL,not active,5900,ic50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)CNC(=O)C(c1cccnc1)N(C(=O)[C@H]1CCCN1C#N)c1ccc(C(C)(C)C)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCC(F)(F)CC1)[C@H](c1cncnc1)N(C(=O)[C@H](F)Cl)c1ccc(-c2cncs2)cc1,3CL,not active,25000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
C=C(C)[C@@H]1CC[C@]2(C(=O)O)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]43C)[C@@H]12,3CL,not active,10000,ic50,CN113181339A, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc(CN(C(=O)Cn2nnc3ccccc32)c2ccc(NC(=O)C3CCC3)cc2)c1,3CL,not active,8100,ic50,CN113181339A, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)CCl)C(C(=O)NC2CCCCC2)c2cncc(O)c2)cc1,3CL,not active,1040,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)OC1CC2CCC(C1)N2C(=O)OCc1ccccc1)C(=O)N[C@H](C=O)C[C@@H]1CCNC1=O,3CL,not active,100000,CC50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)CN(C#N)[C@@H](C(=O)N(c2ccc(C(C)(C)C)cc2)C(C(=O)NC2CCCCC2)c2cccnc2)CO1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
C=CS(=O)(=O)N(c1ccc(C(C)(C)C)cc1)[C@@H](C(=O)NC1CCCCC1)c1cccnc1,3CL,not active,35960,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCCCC1)C(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC1CC1)NC(=O)c1cc2ccccc2[nH]1,3CL,not active,4900,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@@]2(C)CCCN2)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H]1C[C@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)Nc2ccc3c(c2)OCCO3)c2cccnc2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(CC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnc2ccccc2n1)C(=O)C(=O)NCc1ccccc1)NC1CCCCC1,3CL,not active,3800,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(O)c1cccc(N2N=C(c3ccccc3)/C(=C/c3ccc(OCc4ccccc4)cc3)C2=O)c1,3CL,not active,15700,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C[C@H](Cc1c[nH]cn1)NC[C@@H]1C[C@H]2CCCC[C@@H]2CN1C(=O)c1ccc(Br)cc1,3CL,not active,63000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C(=O)Nc1ccc(N(C(=O)Cn2nnc3ccccc32)C(C(=O)NC(C)(C)C)c2ccn(C)c2)cc1,3CL,not active,4100,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)c1c[nH]c(SSc2ccccc2[N+](=O)[O-])n1,3CL,not active,2000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CN1CN(C(=O)C(c2cccnc2)N(C(=O)[C@H]2CCCN2C#N)c2ccc(C(C)(C)C)cc2)CC1=O,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Oc1ccc(OC(=O)c2cc(B(O)O)cc([N+](=O)[O-])c2)cc1)c1cc(B(O)O)cc([N+](=O)[O-])c1,3CL,not active,6700,Ki,WO2021212039A1,Over 100 nM
CCOC(=O)NCCN(C)C(=O)CC[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1)C(=O)N(C)OC,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCC(F)(F)CC1)C(c1cncnc1)N(C(=O)CS)c1ccc(-c2cncs2)cc1,3CL,not active,25000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)OC(=O)Nc1cccn([C@@H](CC2CCCCC2)C(=O)N[C@@H](C[C@@H]2CCNC2=O)C(=O)C(=O)NC2CC2)c1=O,3CL,not active,2390,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N[C@H](C(=O)NCC(=O)NC1C(CN[C@H](C=O)Cc2c[nH]cn2)NC[C@H]2CCCC[C@H]12)C(C)O,3CL,not active,26000,ic50,WO2018042343A2, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H]1C[C@H](C(=O)N(c2ccc(C(C)(C)C)cc2)C(C(=O)NC2CCC(F)(F)CC2)c2cccnc2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2NCC2(C)C)[C@H](C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H]1C[C@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)NC2CCC(F)(F)CC2)c2ccnnc2)N(C#N)C1,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)C2c3ccccc3CN2C#N)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C[C@H](Cc1c[nH]cn1)NC[C@H]1C[C@@H]2CCCC[C@H]2CN1C(=O)c1ccc(Br)cc1,3CL,not active,175000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)C2CC(O)CN2C#N)C(C(=O)NC2CCCCC2)c2cncc(Cl)c2)cc1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)OC1CC2CCC(C1)N2C(=O)OC(C)(C)C)C(=O)N[C@H](C=O)C[C@@H]1CCNC1=O,3CL,not active,100000,CC50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@H](C=O)Cc1ccccc1,3CL,not active,20000,ic50,WO2021151265A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2CCCN2C#N)C(C(=O)NCCN2CCOCC2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
N#CN1C[C@H]2C[C@H]2[C@@H]1C(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)NC1CCC(F)(F)CC1)c1cnccc1C(F)(F)F,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCCCC1)C(c1cccnc1)N(CCc1ccccc1F)C(=O)CCl,3CL,not active,2300,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)NC(=O)C(c1cccnc1)N(C(=O)C1CCCN1C#N)c1ccc(C(C)(C)C)cc1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc(CN(C(=O)Cn2nnc3ccccc32)c2ccc(NC(=O)C3CC3)cc2)c1,3CL,not active,4100,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@@H]1NC(=O)OC(Cc2ccccc2)CC/C=C/CC(C(=O)N(C)C)C[C@@H](C=O)NC1=O,3CL,not active,136900,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)c2cnc[nH]2)C(C(=O)NC2CCCCC2)c2ncc(Cl)nc2C#N)cc1,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1cc(F)c(NC(=O)[C@@H](c2cncnc2)N(C(=O)CCl)c2ccc(-c3ccns3)cc2)c(F)c1,3CL,not active,3060,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)C(F)(F)F,3CL,not active,116000,Ki,WO2021219089A1,Over 100 nM
CC(C)C[C@H](NC(=O)c1cc2ccccc2[nH]1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)C(=O)NCc1ccccc1,3CL,not active,25200,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CCC(=O)Nc1ccc(N(Cc2ccn(C)c2)C(=O)Cn2nnc3ccccc32)cc1,3CL,not active,2900,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(CCc1ccccc1)C(=O)CC[C@@H](C=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCCCC1CCCCCC(C(=O)N(C)C)C[C@@H](C=O)NC(=O)[C@H](CC(C)C)NC1=O,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
C=CC(=O)N(c1ccc(-c2cncs2)cc1)C(C(=O)NC1CCC(F)(F)CC1)c1cncnc1,3CL,not active,25000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCCCC1)C(c1cccnc1)N(C(=O)CCl)c1ccc2ccoc2c1,3CL,not active,4670,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(c1ccc(-c2ccc(Cl)cc2)o1)C(F)(F)c1cncc(Br)c1,3CL,not active,57000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CON(C)C(=O)[C@H](CC(C)C(=O)N(C)CCc1ccccc1)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H]1C[C@H](C(=O)N(c2ccc(C(C)(C)C)cc2)C(C)(C(=O)NC2CCCCC2)c2cccnc2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1CN(C#N)[C@H]1C(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)NC1CCC(F)(F)CC1)c1cncc(F)c1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H]1C[C@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)NC2CCC(F)(F)CC2)c2cncc(F)c2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2CCN2C#N)[C@@H](C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCCCCC(=O)N[C@@H](CC(C)C)C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)F,3CL,not active,50000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccncc1C(C(=O)NC1CCC(F)(F)CC1)N(C(=O)[C@H]1C[C@@](C)(O)CN1C#N)c1ccc(S(F)(F)(F)(F)F)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1ccc(C(C(=O)NC(C)(C)C)N(C(=O)Cn2nnc3ccccc32)c2ccc(NC(=O)C3CC3)cc2)c1,3CL,not active,9100,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)CN(C)C(=O)CC[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1)C(O)P(=O)(OCC)OCC,3CL,not active,169000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](NC(=O)C(c1cccnc1)N(C(=O)c1ccco1)c1ccc(-c2ccccc2)cc1)c1ccccc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCCCC1CC/C=C/CC(C(=O)NC)C[C@@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)O1,3CL,not active,30000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOCCOCCN(C)C(=O)CC[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1)C(=O)N(C)OC,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCC(F)(F)CC1)[C@H](c1cncnc1)N(C(=O)[C@H]1CO1)c1ccc(-c2cnco2)cc1,3CL,not active,25000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2COCCN2)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2CCCN2C#N)C(C(=O)NCC(=O)N2CCOCC2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1CCN(C(=O)c2ccc3c(c2)C(=O)C(=O)N3Cc2ccc3ccccc3c2)CC1,3CL,not active,19730,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2NCC2(C)C)[C@@H](C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1OCCN(C#N)[C@H]1C(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)NC1CCOCC1)c1cncc(F)c1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(-c2cc(=O)c3c(O)cc(O)c(-c4cc(-c5cc(=O)c6c(O)cc(OC)cc6o5)ccc4OC)c3o2)cc1,3CL,not active,38400,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)c1cc2c(Cl)cc(Cl)cc2[nH]1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)C(=O)NC(C)(C)C,3CL,not active,6500,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(S(=O)(=O)CNC(=O)C(c2cncnc2)N(C(=O)CCl)c2ccc(-c3cnco3)cc2)cc1,3CL,not active,2510,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccnc(C)c1C(C(=O)NC1CCC(F)(F)CC1)N(C(=O)[C@H]1C[C@@](C)(O)CN1C#N)c1ccc(S(F)(F)(F)(F)F)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
NC(=O)c1nc(C2CC2)ccc1N(C(=O)c1cnc[nH]1)C(C(=O)NC1CCCCC1)c1cccnc1,3CL,not active,10000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NCc1ccccc1)C(=O)[C@H](C[C@@H]1CCCNC1=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)c1cc2c(F)c(F)ccc2[nH]1,3CL,not active,8800,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
N#CN1C[C@@H](OC(F)F)C[C@@H]1C(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)NC1CCC(F)(F)CC1)c1cncc(F)c1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCCCC1CCCCCCCC(C(=O)N(C)C)C[C@@H](C(=O)N(C)OC)NC(=O)[C@H](CC(C)C)NC1=O,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
C=C(Cl)/C=C1\CSC(C(=O)CC2OC(=O)C(Cl)=C2Cl)=C1C,3CL,not active,7000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)/C=C/c1ccccc1,3CL,not active,2240,Ki,WO2021188620A1,Over 100 nM
CC1(C)CN[C@@H](C(=O)N(c2ccc(C(C)(C)C)cc2)C(C(=O)NC2CCCCC2)c2cccnc2)CO1,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=c1c(O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12,3CL,not active,49730,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCCCC1CC/C=C/CC(C(=O)NC)C[C@@H](C(=O)N(C)OC)NC(=O)[C@H](CC(C)C)NC(=O)O1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2C[C@@](C)(O)CN2C#N)C(C(=O)NC2CCOCC2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1cnc2cc(NC(=O)c3ccc(Cl)cc3)ccc21,3CL,not active,18200,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@]1(O)C[C@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)NC2CCC(F)(F)CC2)c2cccnc2F)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCCCC1CCCC/C=C/CC(C(=O)NC)C[C@@H](CO)NC(=O)[C@H](CC(C)C)NC1=O,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCCCC1CCC/C=C/CC2(CCNC2=O)C[C@@H](C(O)P(=O)(OCC)OCC)NC(=O)[C@H](CC(C)C)NC1=O,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCCCC1CC/C=C/CC(C(=O)N(C)C)C[C@@H](C=O)NC(=O)[C@H](CC(C)C)NC(=O)O1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
[2H]C([2H])(OC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C=O)C[C@@H]1CCNC1=O)C12CC3CC(CC(C3)C1)C2,3CL,not active,100000,CC50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
Fc1ccc(SSc2nccs2)cc1,3CL,not active,2200,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOP(=O)(OCC)C(O)[C@H](CCC(=O)N(CC)CCc1ccccc1)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,9700,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)CCl)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,1140,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
[2H]C([2H])(OC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C=O)C[C@@H]1CCNC1=O)C12CC3CC(CC(O)(C3)C1)C2,3CL,not active,100000,CC50,WO2021205290A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2CC(F)(F)CN2C#N)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCNC(=O)NCCN(C)C(=O)CC[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1)C(O)P(=O)(OCC)OCC,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
N#CN1C[C@H](OC(F)F)C[C@@H]1C(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)NC1CCC(F)(F)CC1)c1cncc(F)c1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H]1C[C@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)NCC(=O)N2CCCC2)c2cccnc2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
N#CN1CC(=O)NC[C@@H]1C(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)NC1CCOCC1)c1cccnc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2COCCN2C#N)[C@@H](C(=O)NC2CCC(F)(F)CC2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](NC(=O)C(c1cncc(F)c1)N(C(=O)[C@H]1C[C@@](C)(O)CN1C#N)c1ccc(-c2ccccc2)cc1)c1ccccc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@]1(O)C[C@H](C(=O)N(c2ccc(-c3ccccc3)cc2)C(C(=O)NC2CCC(F)(F)CC2)c2cnccc2C(F)(F)F)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCCNC(=O)C(c1cccnc1)N(C(=O)[C@H]1CCCN1C#N)c1ccc(C(C)(C)C)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)c1ccc(C(=O)N[C@@H](Cc2ccccc2)C(=O)Nc2ccccc2)cc1,3CL,not active,10000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H]1C[C@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)NCCc2cccc(F)c2)c2cccnc2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)OCC1CC2C=CCC(C2)C1)C(=O)N[C@H](C=O)C[C@@H]1CCNC1=O,3CL,not active,100000,CC50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccccc1CN(C(=O)CCl)C(C(=O)NC1CCCCC1)c1cccnc1,3CL,not active,8650,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2CC(=O)CN2C#N)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
NC(=O)c1nc(C2CC2)ccc1N(C(=O)c1cnc[nH]1)[C@@H](C(=O)NC1CCCCC1)c1cccnc1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)c2nsnc2C(N)=O)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)CCN(C#N)[C@H]1C(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)NC1CCC(F)(F)CC1)c1cncc(F)c1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(N(C(=O)CCl)C(C(=O)NC2CCCCC2)c2cccnc2)c1,3CL,not active,25000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(O)CN(C(=O)C(c2cccnc2)N(C(=O)[C@H]2CCCN2C#N)c2ccc(C(C)(C)C)cc2)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N(C)C)C(=O)Cn1[nH]c(=O)c2ccccc2c1=O)C(C)OCc1ccccc1)C(C)C,3CL,not active,64000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)CCl)C(C(=O)NC2CCCCC2)c2c[nH]c3ncccc23)cc1,3CL,not active,2490,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)c1cc2c(O)cc(C(F)(F)F)cc2o1,3CL,not active,4300,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=c1cc(-c2ccc(O)c(-c3c(O)cc(O)c4c(=O)cc(-c5ccc(O)cc5)oc34)c2)oc2cc(O)cc(O)c12,3CL,not active,8300,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
N#CN1CCOC[C@@H]1C(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)NC1CCC(F)(F)CC1)c1cccnc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)OCC1CC2CCCC(C2)C1)C(=O)N[C@H](C=O)C[C@@H]1CCNC1=O,3CL,not active,100000,CC50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CONC(=O)[C@H](CCC(=O)N(C)CCc1ccccc1)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCC(F)(F)CC1)[C@@H](c1cncnc1)N(C(=O)[C@H](F)Cl)c1ccc(-c2cncs2)cc1,3CL,not active,6940,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)CCNC(=O)C(c1cccnc1)N(C(=O)[C@H]1CCCN1C#N)c1ccc(C(C)(C)C)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCC(F)(F)CC1)C(c1cncc(F)c1)N(C(=O)C1CCC1(O)O)c1ccc(S(F)(F)(F)(F)F)cc1,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N(C)C)C(=O)Cn1[nH]c(=O)c2c([N+](=O)[O-])cccc2c1=O)C(C)O)C(C)C,3CL,not active,53000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1C(=O)N(Cc2ccc(F)cc2Cl)c2ccc(I)cc21,3CL,not active,9400,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCCCC1)C(c1cccnc1)N(Cc1cccc(C(F)(F)F)c1)C(=O)CCl,3CL,not active,1270,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@H](NC(=O)c1cc2c(OC)cccc2[nH]1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)CCl,3CL,not active,42000,ec50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)CCl)C(C(=O)NC2CCCCC2)c2cccnc2)c(Br)c1,3CL,not active,25000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)OCc2cc(N(C(=O)CCl)C(C(=O)Nc3cncc4ccccc34)c3ccno3)cnc21,3CL,not active,19390,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)[C@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)CCl,3CL,not active,2000000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CCS(=O)(=O)NCCN(C)C(=O)CC[C@@H](C=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,36000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](C(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC1CCCCC1)c1cccnc1)N(C)C#N,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(CCN(C(=O)CCl)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,1380,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(O)c1cccc(N2N=C(c3ccccc3)/C(=C/c3ccc(-c4ccccc4)cc3)C2=O)c1,3CL,not active,6700,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1nc(-c2nc(-c3ccnc(SCC(=O)Nc4ccc(Cl)cc4)n3)cs2)cs1,3CL,not active,14000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
N#Cc1c(-c2cccc([N+](=O)[O-])c2)nc(SCc2ccccc2)[nH]c1=O,3CL,not active,50000,ic50,WO2021205290A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)NC(=O)CC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cc2ccccc2[nH]1)C(=O)C(=O)NCC1CCCCC1,3CL,not active,10300,ic50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCCCC1CC/C=C\CC(C(=O)N(C)C)C[C@@H](C(=O)N(C)OC)NC(=O)[C@H](CC(C)C)NC1=O,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CON(C)C(=O)[C@H](CCC(=O)N(C)CCc1cccc(Cl)c1)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)c2nsnc2Cl)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCN(C)C(=O)CC[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1)C(=O)N(C)OC,3CL,not active,89800,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCCCCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]1CCC(=O)N(C)C1(O)C(=O)NC(C)C,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CON(C)C(=O)[C@H](CCC(=O)N(C)CCc1ccncc1)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCCCCCC(=O)N[C@@H](CC(C)C)C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)F,3CL,not active,50000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C1C(=O)N(Cc2cc3ccccc3s2)c2c1cccc2[N+](=O)[O-],3CL,not active,2000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H]1O[C@H](c2c(-c3ccc(O)c(O)c3)oc3cc(O)cc(O)c3c2=O)[C@@H](O)[C@H](O)[C@@H]1O,3CL,not active,24140,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Cc1cncc(Br)c1)c1ccc(-c2ccc(Cl)cc2)o1,3CL,not active,13000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
Nc1cc(B(O)O)cc(C(=O)OCc2cccc(B(O)O)c2)c1,3CL,not active,3500,Ki,WO2018042343A2,Over 100 nM
CC(C)(C)c1ccc(N(C(=O)c2c[nH]cn2)C(C(=O)NC2CCCC2)c2cccnc2)cc1,3CL,not active,1700,ic50,WO2018042343A2, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(=O)c1nc2ccccc2[nH]1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)COC(=O)c1c(Cl)cccc1Cl,3CL,not active,10000,ec50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)C[C@H](NC(=O)COC1CCCCC1)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,not active,1790,Ki,CN113321650A,Over 100 nM
CCOP(=O)(OCC)C(O)[C@H](CCC(=O)N(C)c1ccccc1)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)C(=O)C1CCCC(NC(=O)C(c2cncnc2)N(C(=O)CCl)c2ccc(-c3cnco3)cc2)C1,3CL,not active,1150,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)/C=C/[C@H](Cc1ccccc1)NC(=O)[C@@H](CC(=O)[C@@H](NC(=O)c1cc(C)on1)C(C)C)Cc1ccccc1,3CL,not active,13000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(CSc1nc(C2CCCCC2)nc2ccccc12)NCc1ccco1,3CL,not active,18200,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
OC[C@H]1O[C@@H](n2cnc3c(Cl)ncnc32)[C@H](O)[C@@H]1O,3CL,not active,48700,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H]1C[C@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)N2CC3(COC3)C2)c2cccnc2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)C1CN(C(=O)C(c2cccnc2)N(C(=O)[C@H]2CCCN2C#N)c2ccc(C(C)(C)C)cc2)C1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C(=O)N(c2ccc(C(C)(C)C)cc2)C(C(=O)NC2CCCCC2)c2cccnc2)CN(C#N)C1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOP(=O)(OCC)C(O)[C@@H]1CC(C(=O)NC)C/C=C/CCC(Cc2ccccc2)OC(=O)N[C@@H](CC(C)C)C(=O)N1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
N#Cc1cc(OC(F)(F)F)ccc1N(C(=O)CCl)[C@H](C(=O)NC1CCCCC1)c1cccnc1,3CL,not active,1940,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(CSc1nccc(-c2csc(-c3ccccc3)n2)n1)Nc1cc(Cl)cc(Cl)c1,3CL,not active,3000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOP(=O)(OCC)C(O)[C@H](CCC(=O)N(C)Cc1ccccc1)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)OCC(=O)N[C@@H](CC(C)(C)C)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,not active,4500,Ki,WO2021188620A1,Over 100 nM
CC(=O)c1ccc(NC(=O)[C@@H](c2cnccn2)N(C(=O)CCl)c2ccc(-c3ccns3)cc2)[nH]1,3CL,not active,1150,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NCc1ccccc1)C(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cn2cc(Br)ccc2n1,3CL,not active,4700,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)C2CNC2)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2CCCN2C#N)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)CCl)[C@](C)(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,9600,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)c1cc2c(O)cc(C(F)(F)F)nc2o1,3CL,not active,7000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1cnnc1C(C(=O)NC1CCCCC1)N(C(=O)[C@H]1C[C@@H](O)CN1C#N)c1ccc(C(C)(C)C)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(CCc1cccc(Cl)c1)C(=O)CC[C@@H](C=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)NC(=O)C(c1cccnc1)N(C(=O)c1cccs1)c1ccc(C(C)(C)C)cc1,3CL,not active,50000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(O)c1ccc(/C=C2\C(=O)N(c3ccc(F)cc3)NC2c2ccccc2)cc1,3CL,not active,6800,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCCCCC(=O)N[C@@H](CC(C)C)C(=O)NC(C)(C=O)CCC(=O)N(C)C,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(C(C(=O)NCc2ccccc2)N(C(=O)CN2N=NC3=CC=CC32)c2ccc(NC(=O)C(C)C)cc2)cc1,3CL,not active,1100,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCC(F)(F)CC1)C(c1cncnc1)N(C(=O)CF)c1ccc(-c2cncs2)cc1,3CL,not active,11410,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@@H]1NC(=O)[C@@H](NC(=O)OCc2ccccc2)Cc2cn(nn2)CCCNC(=O)CC[C@@H](C=O)NC1=O,3CL,not active,15500,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)CN(C#N)[C@@H](C(=O)N(c2ccc(C(C)(C)C)cc2)C(C(=O)NC2CCOCC2)c2cccnc2)CO1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCC(F)(F)CC1)C(c1cncnc1)N(C(=O)[C@@H]1CO1)c1ccc(-c2cnco2)cc1,3CL,not active,6450,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCCCC1)C(c1cccnc1)N(CCc1ccccc1Cl)C(=O)CCl,3CL,not active,2650,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCCCC1)C(c1cccnc1)N(CCc1c[nH]c2ccncc12)C(=O)CCl,3CL,not active,1180,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CON(C)C(=O)[C@H](CCC(=O)N(C)CC(C)c1ccccc1)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(Cc1cncc(Br)c1)c1cnc(-c2ccc(Cl)cc2)o1,3CL,not active,75000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
Nc1ncc(S(=O)(=O)c2ccc(Cl)cc2)c(N)n1,3CL,not active,6000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(=O)Nc1ccc(N(C(=O)Cn2cc(-c3ccccc3)nn2)C(C(=O)NC(C)(C)C)c2ccn(C)c2)cc1,3CL,not active,11000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(CCc1cccc(Cl)c1)C(=O)CC[C@@H](CO)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@]1(O)C[C@H](C(=O)N(c2ccc(-c3ccccc3)cc2)C(C(=O)NC2CCC(F)(F)CC2)c2cncc(F)c2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)C2CN(C#N)C2)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CON(C)C(=O)[C@H](CCC(=O)N(C)CCc1ccc(Cl)cc1)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,30000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CO[C@@H]1C[C@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)NCC2(C)COC2)c2cccnc2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2C[C@@H](F)CN2C#N)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2N(C#N)CC2(C)C)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
Cn1nc(-c2ccc(-c3ccnc(SCC(=O)Nc4ccc(Cl)cc4)n3)s2)cc1C(F)(F)F,3CL,not active,10000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2C[C@@H](O)CN2C#N)C(C(=O)NCCN2CCOCC2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2C[C@@H](O)CN2C#N)C(C(=O)NC2CCCCC2)c2cncc(C(F)(F)F)c2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(CN(C(=O)CCl)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,4820,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1oc(C(C)(C)C)cc1-c1cc(NS(=O)(=O)c2cccs2)[nH]n1,3CL,not active,10000,ic50,WO2021205290A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOP(=O)(OCC)C(O)[C@H](CC1CCNC1=O)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1,3CL,not active,1100,ec50,US20150133368A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)/C=C/[C@H](CCC(=O)N(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(C)=O)C(C)C,3CL,not active,330000,Ki,US20150133368A1,Over 100 nM
O=C(NC1CCCCC1)C(c1cccnc1)N(C(=O)CCl)c1ccc(Br)cc1F,3CL,not active,2130,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)c1ccc(C(=O)N[C@@H](Cc2ccccc2)C(=O)Nc2ccccc2Cl)cc1,3CL,not active,10000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCC1CCCC/C=C/CC(C(=O)NC)C[C@@H](C(O)P(=O)(OCC)OCC)NC(=O)[C@H](CC(C)C)NC1=O,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)O[C@@H]1C[C@H](C(=O)N(c2ccc(C(C)(C)C)cc2)C(C(=O)NC2CCCCC2)c2cccnc2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)OC(=O)N1CC(C)(C(=O)N(c2ccc(C(C)(C)C)cc2)C(C(=O)NC2CCCCC2)c2cccnc2)C1,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)CNC(=O)c3ccccc3C#N)cc12,3CL,not active,100000,ec50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1nc2ccc(N(C(=O)[C@H]3C[C@@H](O)CN3C#N)C(C(=O)NC3CCCCC3)c3cccnc3)cc2[nH]1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)C[C@H](C(=O)N(c2ccc(C(C)(C)C)cc2)C(C(=O)NC2CCCCC2)c2cccnc2)N(C#N)C1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)CN(C#N)[C@@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)NC2CCC(F)(F)CC2)c2cncc(F)c2)CO1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc2c(c1)N[Zn]S2,3CL,not active,1400,Ki,WO2021212039A1,Over 100 nM
CC(C)(C)C[C@H](NC(=O)C1CCCCC1)C(=O)N[C@@H](C#N)C[C@@H]1CCNC1=O,3CL,not active,37000,ec50,CN113197895A, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)C[C@H](NC(=O)c1csc(C(F)(F)F)n1)C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,not active,1930,Ki,CN113197895A,Over 100 nM
N#CN1CC(=O)NCC1C(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)NC1CCOCC1)c1cccnc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCCCCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)NC)CSSC[C@H](CCC(=O)NC)NC(=O)[C@H](CC(C)C)NC(=O)CCCCCCCC,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(N(C(=O)CCl)C(C(=O)NC2CCCCC2)c2cccnc2)cc1C,3CL,not active,25000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
COC(C)(C)CNC(=O)C(c1cccnc1)N(C(=O)[C@H]1CCCN1C#N)c1ccc(C(C)(C)C)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C[C@H](CCC(=O)N1CCOC(c2ccccc2)C1)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCCC1CCC/C=C\CC(C(=O)N(C)C)C[C@@H](C(=O)N(C)OC)NC(=O)[C@H](CC(C)C)NC(=O)O1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)/C=C/[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(F)cc1)NC(=O)[C@@H](NC(=O)c1cc(C)on1)C(C)C,3CL,not active,39000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
OCC1C(COCc2ccccc2)CC1n1cnc2c(Cl)ncnc21,3CL,not active,14500,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCN(C)C(=O)CC[C@@H](C=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,3200,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)NC(=O)C(c1cccnc1)N(C(=O)c1ccco1)c1ccc(C(C)(C)C)cc1,3CL,not active,4200,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
O=[N+]([O-])c1ccccc1SSc1nccs1,3CL,not active,2000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)c2cnc[nH]2)C(C(=O)NC2CCCCC2)c2nccnc2Cl)cc1,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)/C=C/[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)c1cc(C)on1)C(C)C,3CL,not active,9100,Ki,WO2021212039A1,Over 100 nM
CON(C)C(=O)[C@H](CCC(=O)N(C)C)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(S(=O)(=O)CNC(=O)C(c2cnccn2)N(C(=O)CCl)c2ccc(-c3cnco3)cc2)cc1,3CL,not active,1500,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)NC(=O)C(c1cccnc1)N(C(=O)c1c[nH]cn1)c1ccc(C(C)(C)C)cc1,3CL,not active,6000,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@H]2CCCN2C#N)C(C(=O)N2CC(F)C2)c2cccnc2)cc1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)CCl)cc12,3CL,not active,10000,ec50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)[C@@H]2CCCN2C#N)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)[C@H](NS(=O)(=O)C(F)(F)F)C(=O)N1CC[C@H](C(C)(C)C)C[C@@H]1C(=O)N[C@H](C#N)C[C@@H]1CCNC1=O,3CL,not active,8160,Ki,WO2021212039A1,Over 100 nM
CC(C)(C)c1ccc(N(C(=O)c2scnc2C#N)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,30000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(C)c1ccc(N(C(=O)C2CCN2C#N)C(C(=O)NC2CCCCC2)c2cccnc2)cc1,3CL,not active,2000,ec50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(N[C@@H](Cc1ccccc1)C(=O)Nc1ccc([N+](=O)[O-])cc1Cl)c1ccccc1,3CL,not active,10000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc2[nH]c(C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)CCl)cc12,3CL,not active,7500,ec50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)c1ccc(C(=O)N[C@@H](Cc2ccccc2)C(=O)Nc2ccc([N+](=O)[O-])cc2)cc1,3CL,not active,10000,ic50,WO2005113580A1, not Ki or Kd; not used in NCI fingerprint analysis
CCOCCOCCN(C)C(=O)CC[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1cccc(Cl)c1)C(O)P(=O)(OCC)OCC,3CL,not active,200000,ic50,WO2021188620A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C[C@H](Cc1c[nH]cn1)NCC1CC2CCCCC2CN1C(=O)c1ccccc1,3CL,not active,68000,ic50,US20150133368A1, not Ki or Kd; not used in NCI fingerprint analysis
CC1(C)CN(C#N)[C@@H](C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(C(=O)NC2CCC(F)(F)CC2)c2cccnc2)CO1,3CL,not active,2000,ic50,WO2021212039A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(NC1CCC(F)(F)CC1)C(c1ccnnc1)N(C(=O)C1CO1)c1ccc(-c2ccno2)cc1,3CL,not active,25000,ic50,WO2021219089A1, not Ki or Kd; not used in NCI fingerprint analysis
O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1cc2ccccc2[nH]1,VDR,active,0.029,Ki,US9550741,Below 1 nM
O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1cc2ccccc2s1,VDR,active,0.035,Ki,US9550741,Below 1 nM
O=S(=O)(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1cccs1,VDR,active,0.043,Ki,US9550741,Below 1 nM
O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1cccs1,VDR,active,0.056,Ki,US9550741,Below 1 nM
CCOC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1,VDR,active,0.058,Ki,US9550741,Below 1 nM
O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)OCc1ccccc1,VDR,active,0.061,Ki,US9550741,Below 1 nM
O=S(=O)(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1ccco1,VDR,active,0.062,Ki,US9550741,Below 1 nM
O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)Nc1cccnc1,VDR,active,0.068,Ki,US9550741,Below 1 nM
O=C(N[C@@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1cc2ccccc2[nH]1,VDR,active,0.071,Ki,US9550741,Below 1 nM
O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1cc2ccccc2o1,VDR,active,0.078,Ki,US9550741,Below 1 nM
O=S(=O)(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1cc2ccccc2o1,VDR,active,0.085,Ki,US9550741,Below 1 nM
COC(=O)N[C@@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1,VDR,active,0.087,Ki,US9550741,Below 1 nM
CN(C)C(=O)NC1CCC(CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1,VDR,active,0.09,Ki,US9550741,Below 1 nM
O=S(=O)(N[C@@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1ccc[nH]1,VDR,active,0.093,Ki,US9550741,Below 1 nM
CC(C)COC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1,VDR,active,0.093,Ki,US9550741,Below 1 nM
O=C(Cc1cccs1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1,VDR,active,0.1,Ki,US9550741,Below 1 nM
COC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1,VDR,active,0.1,Ki,US9550741,Below 1 nM
C[C@@H](CCCCO)C1CCC2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(C)[C@H](O)C1,VDR,active,0.1,Ki,10.1016/j.bioorg.2013.01.001,Below 1 nM
CN(C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1ccccc1,VDR,active,0.13,Ki,US9550741,Below 1 nM
O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1ccco1,VDR,active,0.13,Ki,US9550741,Below 1 nM
O=C(NCc1ccccc1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1,VDR,active,0.18,Ki,US9550741,Below 1 nM
O=C(Cc1coc2ccccc12)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1,VDR,active,0.18,Ki,US9550741,Below 1 nM
O=C(N[C@@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1cccs1,VDR,active,0.19,Ki,US9550741,Below 1 nM
CCCC[C@H](C)C1CCC2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(C)[C@H](O)C1,VDR,active,0.2,Ki,10.1016/j.bioorg.2013.01.001,Below 1 nM
C[C@H](CCCCO)C1CCC2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,0.2,Ki,10.1016/j.bioorg.2013.01.001,Below 1 nM
O=S(=O)(N[C@@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1cccs1,VDR,active,0.23,Ki,US9550741,Below 1 nM
O=C(N[C@@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1ccco1,VDR,active,0.25,Ki,US9550741,Below 1 nM
CC(C)c1onc(c1COc1ccc(cc1)-c1nc2ccc(cc2n1C1CC1)C(O)=O)-c1c(Cl)cccc1Cl,VDR,not active,3198,IC50,PMID:32616182, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1CCOCC(O)C(O)COCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)C(C)(C)NC1=O)C(O)=O,VDR,not active,3200,IC50,10.1016/j.bmcl.2013.06.002, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ccccc2c1C(Nc1ccc(Cl)cc1)c1cccnc1,VDR,not active,3200,IC50,10.1021/ml400462j, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(cc1)C(Nc1ccc(OC)c(OC)c1)c1c(C)[nH]c2ccccc12,VDR,not active,3200,IC50,10.1021/ml400462j, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)c1ccccc1OCc1oc(nc1C)-c1ccccc1OC,VDR,not active,3250,IC50,10.1016/j.bmcl.2017.12.041, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](C[C@H]1C[C@@](C)(O)C(=O)N1CCc1ccccc1)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,not active,3300,IC50,10.1016/j.bmcl.2010.01.079, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)c1ccc2c(c1)C(C)(C)C(\C=C\c1ccc(OC)cc1)=[N+]2C,VDR,not active,3300,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(c1)-c1nc(C)c(COc2ccc(CCC(O)=O)cc2)o1,VDR,not active,3350,IC50,10.1016/j.bmcl.2017.12.041, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2cc(C)ccc2c1C(NCc1ccc(C)cc1)c1ccccc1Cl,VDR,not active,3400,IC50,10.1021/ml400462j, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1onc(c1COc1ccc(-c2nc3ccc(cc3n2C)C(O)=O)c(Cl)c1)-c1c(Cl)cccc1Cl,VDR,not active,3519,IC50,PMID:32616182, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1)C(=O)NCCCN1CCOCC1,VDR,not active,3521,IC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1onc(c1COc1ccc(cc1)-c1nc2ccc(cc2n1C(C)C)C(O)=O)-c1c(Cl)cccc1Cl,VDR,not active,3552,IC50,PMID:32616182, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(c1)-c1nc(C)c(COc2ccc(CC(O)=O)cc2)o1,VDR,not active,3600,IC50,10.1016/j.bmcl.2017.12.041, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ccccc2c1C(Nc1ccc(Cl)cc1)c1ccncc1,VDR,not active,3700,IC50,10.1021/ml400462j, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ccccc2c1C(Nc1ccc(Cl)cc1)c1nccs1,VDR,not active,3800,IC50,10.1021/ml400462j, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)Cc1ccc(OCc2oc(nc2C)-c2ccccc2OC)cc1,VDR,not active,3820,IC50,10.1016/j.bmcl.2017.12.041, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(\C=C\C2=[N+](C)c3ccc(OC)cc3C2(C)C)cc1,VDR,not active,3900,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ccccc2c1C(Nc1ccc(Cl)cc1)c1ccccc1Cl,VDR,not active,4200,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1)C(=O)N[C@@H](C)CO,VDR,not active,4300,IC50,10.1016/j.ejmech.2018.08.085, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(NC(c2c(C)[nH]c3ccccc23)c2ccc(cc2)C(F)(F)F)cc1OC,VDR,not active,4400,IC50,10.1021/ml400462j, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ccccc2c1C(Nc1ccc(cc1)[N+]([O-])=O)c1ccccc1Cl,VDR,not active,4400,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1onc(c1COc1ccc(cc1)-c1nc2cc(ccc2n1C)C(O)=O)-c1c(Cl)cccc1Cl,VDR,not active,4408,IC50,PMID:32616182, not Ki or Kd; not used in NCI fingerprint analysis
CCOc1ccc(NC(=O)c2ccc(n2CC)C(CC)(CC)c2ccc(OCCC(O)(CC)CC)c(C)c2)cc1,VDR,not active,4543,IC50,10.1021/acs.jmedchem.8b00106, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)c1ccc(OCc2oc(nc2C)-c2ccccc2OC)cc1,VDR,not active,4850,IC50,10.1016/j.bmcl.2017.12.041, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2cc(C)ccc2c1C(Nc1ccc(OC(F)(F)F)cc1)c1ccccc1Cl,VDR,not active,5000,IC50,10.1021/ml400462j, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2cc(C)ccc2c1C(Nc1ccc(Cl)cc1)c1ccccc1Cl,VDR,not active,5200,IC50,10.1021/ml400462j, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1)C(=O)NCC(OC)OC,VDR,not active,5235,IC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCS(=O)(=O)c1oc(nc1S(=O)(=O)c1ccccc1)-c1cccs1,VDR,not active,5300,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ccccc2c1C(NCc1ccccc1)c1ccccc1Cl,VDR,not active,5400,IC50,10.1021/ml400462j, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncccc1NC(c1c(C)[nH]c2cc(C)ccc12)c1cccnc1,VDR,not active,5400,IC50,10.1021/ml400462j, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)c1cccc(OCc2oc(nc2C)-c2cccc(OC)c2)c1,VDR,not active,5560,IC50,10.1016/j.bmcl.2017.12.041, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)c1ccc(OCc2oc(nc2C)-c2cccc(OC)c2)cc1,VDR,not active,5670,IC50,10.1016/j.bmcl.2017.12.041, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)n1c(nc2ccc(cc12)C(O)=O)-c1ccc(OCc2c(onc2-c2c(Cl)cccc2Cl)C(C)C)cc1,VDR,not active,5688,IC50,PMID:32616182, not Ki or Kd; not used in NCI fingerprint analysis
CCOc1ccc(\C=C\C2=[N+](C)c3ccc(cc3C2(C)C)C(=O)OC)cc1,VDR,not active,5700,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(nc2ccc(cc12)C(O)=O)-c1ccc(OCc2c(onc2-c2c(Cl)cccc2Cl)C(C)C)cc1,VDR,not active,5761,IC50,PMID:32616182, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2cc(C)ccc2c1C(Nc1ccc(cc1)C(F)(F)F)c1ccccc1Cl,VDR,not active,5800,IC50,10.1021/ml400462j, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2cc(C)ccc2c1C(NCc1ccccc1)c1ccccc1Cl,VDR,not active,5800,IC50,10.1021/ml400462j, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(NC(c2c(C)[nH]c3ccccc23)c2ccccc2Cl)cc1,VDR,not active,5800,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ccccc2c1C(Nc1ccc(Cl)cc1)c1ncc[nH]1,VDR,not active,6100,IC50,10.1021/ml400462j, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)CS(=O)(=O)c1oc(nc1S(=O)(=O)c1ccc(F)cc1)-c1cccs1,VDR,not active,6200,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,not active,6430,IC50,10.1016/j.ejmech.2018.08.085, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)CCc1ccc(OCc2oc(nc2C)-c2cccc(OC)c2)cc1,VDR,not active,6700,IC50,10.1016/j.bmcl.2017.12.041, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2cc(C)ccc2c1C(Nc1cccnc1)c1ccccc1Cl,VDR,not active,6700,IC50,10.1021/ml400462j, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)c1ccccc1OCc1oc(nc1C)-c1cccc(OC)c1,VDR,not active,6750,IC50,10.1016/j.bmcl.2017.12.041, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)c1ccc2c(c1)C(C)(C)C(\C=C\c1ccc(O)cc1)=[N+]2C,VDR,not active,6800,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCCCC(=O)N1CCN(CC1)c1ccc(cc1)C(F)(F)F,VDR,not active,7000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CCCS(=O)(=O)c1oc(nc1S(=O)(=O)c1ccc(F)cc1)-c1cccs1,VDR,not active,7100,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1onc(c1COc1ccc(cc1)-c1nc2ccc(cc2n1C)C(O)=O)-c1c(Cl)cccc1Cl,VDR,not active,7151,IC50,PMID:32616182, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(NC(c2c(C)[nH]c3ccccc23)c2ccccc2Cl)cc1OC,VDR,not active,7200,IC50,10.1021/ml400462j, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc2c(C(Nc3ccc(Cl)cc3)c3ccccc3Cl)c(C)[nH]c2c1,VDR,not active,7300,IC50,10.1021/ml400462j, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)c1cccc(OCc2oc(nc2C)-c2ccccc2OC)c1,VDR,not active,7330,IC50,10.1016/j.bmcl.2017.12.041, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(cc1)C(Nc1ccc(cc1)C(F)(F)F)c1c(C)[nH]c2ccccc12,VDR,not active,8100,IC50,10.1021/ml400462j, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ccccc2c1C(Nc1ccccc1)c1ccc(Cl)cc1,VDR,not active,8100,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ccccc2c1C(Nc1ccc(C)cc1)c1ccccc1Cl,VDR,not active,8200,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ccccc2c1C(Nc1ccccc1)c1ccccc1Cl,VDR,not active,8500,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(NC(c2nccs2)c2c(C)[nH]c3ccccc23)cc1OC,VDR,not active,8500,IC50,10.1021/ml400462j, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccccc1NC(c1c(C)[nH]c2ccccc12)c1ccccc1Cl,VDR,not active,8600,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)c1ccc(\C=C\C2=[N+](C)c3ccc(OC)cc3C2(C)C)cc1,VDR,not active,8600,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)c1ccc(NC(c2c(C)[nH]c3ccccc23)c2ccccc2Cl)cc1,VDR,not active,8700,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2cc(C)ccc2c1C(NCc1ccc(cc1)C(F)(F)F)c1ccccc1Cl,VDR,not active,9100,IC50,10.1021/ml400462j, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1ccc(cc1)C(Nc1ccccn1)c1c(C)[nH]c2ccccc12,VDR,not active,9100,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
CCOc1ccc(NC(=O)c2ccc(n2CC)C(CC)(CC)c2ccc(OCC(O)C(C)(C)C)c(C)c2)cc1,VDR,not active,9245,IC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(NC(c2c(C)[nH]c3cc(C)ccc23)c2ccccc2Cl)cc1OC,VDR,not active,9300,IC50,10.1021/ml400462j, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(cc1)C(Nc1ccccn1)c1c(C)[nH]c2ccccc12,VDR,not active,9500,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1onc(c1COc1ccc(\C=C\c2cccc(c2)C(O)=O)c(Cl)c1)-c1c(Cl)cccc1Cl,VDR,not active,10000,IC50,PMID:32616182, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1)C(=O)NCC#C,VDR,not active,10000,IC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1)C(=O)N(CCC#N)CCC#N,VDR,not active,10000,IC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(nc(C2CC2)n1-c1c(Cl)ccc(N2CC3(CC(C3)C(O)=O)C2)c1Cl)C1(CC1)C(F)(F)F,VDR,not active,10000,IC50,10.1021/acs.jmedchem.9b01291, not Ki or Kd; not used in NCI fingerprint analysis
CCCC(CCC)n1c(nc2ccc(cc12)C(O)=O)-c1ccc(OCc2c(onc2-c2c(Cl)cccc2Cl)C(C)C)cc1,VDR,not active,10000,IC50,PMID:32616182, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)n1c(nc2ccc(cc12)C(O)=O)-c1ccc(OCc2c(noc2C(C)C)-c2c(Cl)cccc2Cl)cc1F,VDR,not active,10000,IC50,PMID:32616182, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1onc(c1COc1ccc(cc1)-c1nc2ccc(cc2n1CC1CCC(CC1)C(C)=O)C(O)=O)-c1c(Cl)cccc1Cl,VDR,not active,10000,IC50,PMID:32616182, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1onc(c1COc1ccc(cc1)-c1nc2ccc(cc2n1C1CCN(CC1)C(C)=O)C(O)=O)-c1c(Cl)cccc1Cl,VDR,not active,10000,IC50,PMID:32616182, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)CCc1ccc(OCc2oc(nc2C)-c2ccccc2OC)cc1,VDR,not active,10100,IC50,10.1016/j.bmcl.2017.12.041, not Ki or Kd; not used in NCI fingerprint analysis
CCCCNC(=O)Cn1sc2nc(C)cc(C)c2c1=O,VDR,not active,10500,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
CCc1ccc(cc1)S(=O)(=O)ON1C(=O)c2ccccc2C1=O,VDR,not active,10500,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ccccc2c1C(Nc1ccccc1)c1ccccc1,VDR,not active,10900,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@@H](CC[C@]4(C)[C@H]3CC[C@]12C)OC(C)=O,VDR,not active,11000,IC50,10.1016/j.ejmech.2016.01.002, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(cc1)C(Nc1ccccc1)c1c(C)[nH]c2ccccc12,VDR,not active,12100,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncccc1NC(c1c(C)[nH]c2cc(C)ccc12)c1ccccc1Cl,VDR,not active,12200,IC50,10.1021/ml400462j, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ccccc2c1C(Nc1ccccc1)c1ccc(cc1)[N+]([O-])=O,VDR,not active,12200,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ccccc2c1C(Nc1ccc(C)c(C)c1)c1ccccc1Cl,VDR,not active,12800,IC50,10.1021/ml400462j, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)CCN1Cc2cc(CC(C)C)c(NCCNC(=O)OC(C)(C)C)cc2N[C@@H](CC(C)C)C1=O,VDR,not active,13000,IC50,10.1016/j.bmcl.2010.01.079, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ccccc2c1C(Nc1ccccc1)c1ccc(CCCO)cc1,VDR,not active,13100,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)c1ccc(cc1)C(Nc1ccccc1)c1c(C)[nH]c2ccccc12,VDR,not active,13500,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C,VDR,not active,13600,IC50,10.1016/j.ejmech.2016.01.002, not Ki or Kd; not used in NCI fingerprint analysis
COCC(=O)Oc1c(Sc2ccc(Cl)cc2)c(C)nn1-c1ccccc1,VDR,not active,13700,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)Cc1ccc(OCc2oc(nc2C)-c2cccc(OC)c2)cc1,VDR,not active,13900,IC50,10.1016/j.bmcl.2017.12.041, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)c1ccc(cc1)-c1cc2CN(CCC(C)C)C(=O)[C@H](CC(C)C)Nc2cc1N,VDR,not active,14000,IC50,10.1016/j.bmc.2012.11.042, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ccccc2c1C(Nc1ccccn1)c1cccc(Br)c1,VDR,not active,14100,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
COc1ncccc1C(Nc1ccc(Cl)cc1)c1c(C)[nH]c2ccccc12,VDR,not active,14100,IC50,10.1021/ml400462j, not Ki or Kd; not used in NCI fingerprint analysis
Clc1ccc(Cn2c(C=O)nc3ccccc23)c(Cl)c1,VDR,not active,14200,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCC(=O)NCCS(O)(=O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C,VDR,not active,14500,IC50,10.1016/j.ejmech.2016.01.002, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ccccc2c1C(Nc1ccccc1)c1ccc(C)cc1,VDR,not active,14600,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ccccc2c1C(Nc1ccccc1)c1ccc2ccccc2c1,VDR,not active,15000,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
COC(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C,VDR,not active,15100,IC50,10.1016/j.ejmech.2016.01.002, not Ki or Kd; not used in NCI fingerprint analysis
Cc1nc2cc(NC(c3c(C)[nH]c4ccccc34)c3ccccc3Cl)ccc2s1,VDR,not active,15800,IC50,10.1021/ml400462j, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)CCN1Cc2cc(C=C(C)C)c(N)cc2N[C@@H](CC(C)C)C1=O,VDR,not active,17000,IC50,10.1016/j.bmcl.2010.01.079, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ccccc2c1C(Nc1ccccn1)c1ccc(Br)cc1,VDR,not active,17200,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)c1ccc(c(OCCO)c1)-c1cc2CN(CCC(C)C)C(=O)[C@H](CC(C)C)Nc2cc1N,VDR,not active,20000,IC50,10.1016/j.bmc.2012.11.042, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1CCOCCCCOCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)C(CO)(CO)NC1=O)C(N)=O,VDR,not active,20000,IC50,10.1016/j.bmc.2015.01.007, not Ki or Kd; not used in NCI fingerprint analysis
CC(Nc1ccccc1)c1c(C)[nH]c2ccccc12,VDR,not active,20100,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
Clc1ccccc1C(Nc1ccccc1)c1c[nH]c2ccccc12,VDR,not active,20300,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
Cc1c(C=O)c(C(O)=O)c(C)n1Cc1ccc(Cl)cc1,VDR,not active,20500,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(cc1)S(=O)(=O)ON1C(=O)c2ccccc2C1=O,VDR,not active,21600,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ccccc2c1C(Nc1ccccn1)c1cccc(F)c1,VDR,not active,22100,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)S(=O)(=O)c1oc(nc1S(=O)(=O)c1ccccc1)-c1cccs1,VDR,not active,22300,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(NC(c2c(C)[nH]c3ccccc23)c2ccc(OC(F)(F)F)cc2)cc1OC,VDR,not active,22800,IC50,10.1021/ml400462j, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@@H](CC[C@]4(C)[C@H]3CC[C@]12C)OS(O)(=O)=O,VDR,not active,23300,IC50,10.1016/j.ejmech.2016.01.002, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)CCN1Cc2cc(c(N)cc2N[C@@H](CC(C)C)C1=O)-c1ccccc1,VDR,not active,24000,IC50,10.1016/j.bmc.2012.11.042, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ccccc2c1C(Nc1ccc(cc1)C(F)(F)F)c1ccccc1Cl,VDR,not active,24000,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ccccc2c1C(Nc1ccc2cccnc2c1)c1ccccc1Cl,VDR,not active,25000,IC50,10.1021/ml400462j, not Ki or Kd; not used in NCI fingerprint analysis
CCCCc1cc2CN(CCC(C)C)C(=O)[C@H](CC(C)C)Nc2cc1N,VDR,not active,25000,IC50,10.1016/j.bmc.2012.11.042, not Ki or Kd; not used in NCI fingerprint analysis
Cc1cccc(c1)N1COc2ccc3ccccc3c2C1,VDR,not active,25000,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ccccc2c1C(Nc1ccccn1)c1cccc(Cl)c1,VDR,not active,25100,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ccccc2c1C(Nc1ccccn1)c1ccc(C)cc1,VDR,not active,27700,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)CCN1Cc2cc(CC(C)C)c(NCCN)cc2N[C@@H](CC(C)C)C1=O,VDR,not active,28000,IC50,10.1016/j.bmcl.2010.01.079, not Ki or Kd; not used in NCI fingerprint analysis
O=Cc1nc2ccccc2n1Cc1ccc2ccccc2c1,VDR,not active,28000,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ccccc2c1C(Nc1ccccn1)c1ccc(F)cc1,VDR,not active,28900,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)CCN1Cc2cc(CC(C)C)c(N)cc2N[C@@H](CC(C)C)C1=O,VDR,not active,30000,IC50,10.1016/j.bmcl.2010.01.079, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)CCN1Cc2ccccc2N[C@@H](CC(C)C)C1=O,VDR,not active,30000,IC50,10.1016/j.bmc.2012.11.042, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)CCN1Cc2cc(I)ccc2N[C@@H](CC(C)C)C1=O,VDR,not active,30000,IC50,10.1016/j.bmc.2012.11.042, not Ki or Kd; not used in NCI fingerprint analysis
CCC(=C)c1ccc2N[C@@H](CC(C)C)C(=O)N(CCC(C)C)Cc2c1,VDR,not active,30000,IC50,10.1016/j.bmc.2012.11.042, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)CCN1Cc2cc(CC(C)C)ccc2N[C@@H](CC(C)C)C1=O,VDR,not active,30000,IC50,10.1016/j.bmc.2012.11.042, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)CCN1Cc2cc(\C=C\CO)ccc2N[C@@H](CC(C)C)C1=O,VDR,not active,30000,IC50,10.1016/j.bmc.2012.11.042, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)CCN1Cc2cc(\C=C\CCO)ccc2N[C@@H](CC(C)C)C1=O,VDR,not active,30000,IC50,10.1016/j.bmc.2012.11.042, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)CCN1Cc2cc(CCCO)ccc2N[C@@H](CC(C)C)C1=O,VDR,not active,30000,IC50,10.1016/j.bmc.2012.11.042, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)CCN1Cc2ccc(N)cc2N[C@@H](CC(C)C)C1=O,VDR,not active,30000,IC50,10.1016/j.bmc.2012.11.042, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)CCN1Cc2cc(I)c(N)cc2N[C@@H](CC(C)C)C1=O,VDR,not active,30000,IC50,10.1016/j.bmc.2012.11.042, not Ki or Kd; not used in NCI fingerprint analysis
CC\C=C\c1cc2CN(CCC(C)C)C(=O)[C@H](CC(C)C)Nc2cc1N,VDR,not active,30000,IC50,10.1016/j.bmc.2012.11.042, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCc1cc2CN(CCC(C)C)C(=O)[C@H](CC(C)C)Nc2cc1N,VDR,not active,30000,IC50,10.1016/j.bmc.2012.11.042, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)CCN1Cc2cc(c(N)cc2N[C@@H](CC(C)C)C1=O)-c1ccc(cc1)C(O)=O,VDR,not active,30000,IC50,10.1016/j.bmc.2012.11.042, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)CCN1Cc2cc(CC(C)C)c(cc2N[C@@H](CC(C)C)C1=O)N=C(N)N,VDR,not active,30000,IC50,10.1016/j.bmcl.2010.01.079, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)CCN1Cc2cc(CC(C)C)c(NCCNC(C)=O)cc2N[C@@H](CC(C)C)C1=O,VDR,not active,30000,IC50,10.1016/j.bmcl.2010.01.079, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(c1)C(Nc1ccccn1)c1c(C)[nH]c2ccccc12,VDR,not active,30300,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@@H](CC[C@]4(C)[C@H]3CC[C@]12C)O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O,VDR,not active,31500,IC50,10.1016/j.ejmech.2016.01.002, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(c1)-c1nc(C)c(COc2ccccc2C(O)=O)o1,VDR,not active,33000,IC50,10.1016/j.bmcl.2017.12.041, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(c1)-c1nc(C)c(COc2cccc(c2)C(O)=O)o1,VDR,not active,33140,IC50,10.1016/j.bmcl.2017.12.041, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCC(=O)N1CCC(CC1)c1ccccc1,VDR,not active,37000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(OC)c(c1)S(=O)(=O)ON1C(=O)c2ccccc2C1=O,VDR,not active,37600,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCCC(=O)N(Cc1ccccc1)Cc1ccccc1,VDR,not active,38000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CCCN(C(=O)CCNC(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O)c1ccccc1,VDR,not active,40000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCC(=O)NCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C,VDR,not active,40100,IC50,10.1016/j.ejmech.2016.01.002, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCCC(=O)NC12CC3CC(CC(C3)C1)C2,VDR,not active,44000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCC(=O)N1CCc2ccccc2C1,VDR,not active,50000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3C[C@H](O)[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C,VDR,not active,50000,IC50,10.1016/j.ejmech.2016.01.002, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3[C@@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C,VDR,not active,50000,IC50,10.1016/j.ejmech.2016.01.002, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C,VDR,not active,50000,IC50,10.1016/j.ejmech.2016.01.002, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C,VDR,not active,50000,IC50,10.1016/j.ejmech.2016.01.002, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCC(=O)N1CCN(CC1)c1ccc(F)cc1,VDR,not active,51000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CC1Cc2ccccc2N1C(=O)CCNC(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,55000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCCC(=O)N1CCc2ccccc2C1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(CC1)C(=O)CNC(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CC1CCN(CC1)C(=O)CNC(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCC(=O)N1CCCCC1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCC(=O)N1CCN(CC1)c1ccc(cc1)C(F)(F)F,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCC(=O)N1CCN(CC1)c1ccccc1F,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCC(=O)N1CCN(CC1)c1ccccc1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)N(C(C)C)C(=O)CNC(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCC(=O)N(Cc1ccccc1)Cc1ccccc1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(Cc1cccc(F)c1)C(=O)CNC(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(Cc1ccccc1F)C(=O)CNC(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(Cc1ccccc1)C(=O)CNC(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCC(=O)N(Cc1ccccc1)c1ccccc1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CCCN(C(=O)CNC(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O)c1ccccc1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(Cc1ccccc1)C(=O)C1CCN(CC1)C(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)N1CCC(CC1)C(=O)N(Cc1ccccc1)c1ccccc1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)N1CCC(CC1)C(=O)N1CCc2ccccc2C1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)N1CCC(CC1)C(=O)NC12CC3CC(CC(C3)C1)C2,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CC1Cc2ccccc2N1C(=O)CN(C)C(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(CC(=O)N1Cc2ccccc2C1)C(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(CC(=O)N1CCc2ccccc12)C(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CC1CCN(CC1)C(=O)CN(C)C(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(CC(=O)N1CCCCC1)C(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(CC(=O)N1CCN(CC1)c1ccc(cc1)C(F)(F)F)C(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(C(=O)CNC(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O)c1ccccc1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCC(=O)NC12CC3CC(CC(C3)C1)C2,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CC1Cc2ccccc2N1C(=O)C1CCN(CC1)C(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)N1CCC(CC1)C(=O)N1Cc2ccccc2C1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)N1CCC(CC1)C(=O)N1CCc2ccccc12,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN1CCN(CC1)C(=O)C1CCN(CC1)C(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CC1CCN(CC1)C(=O)C1CCN(CC1)C(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)N1CCC(CC1)C(=O)N1CCCCC1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)N1CCC(CC1)C(=O)N1CCN(CC1)c1ccc(F)cc1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)N1CCC(CC1)C(=O)N1CCN(CC1)c1ccccc1F,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(cc1)N1CCN(CC1)C(=O)C1CCN(CC1)C(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)N1CCC(CC1)C(=O)N1CCN(CC1)c1ccccc1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)N(C(C)C)C(=O)C1CCN(CC1)C(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)N1CCC(CC1)C(=O)N1CCC(CC1)c1ccccc1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)N1CCC(CC1)C(=O)N(Cc1ccccc1)Cc1ccccc1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(Cc1cccc(F)c1)C(=O)C1CCN(CC1)C(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(Cc1ccccc1F)C(=O)C1CCN(CC1)C(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(CC(=O)N1CCN(CC1)c1ccccc1F)C(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(CC(=O)N1CCN(CC1)c1ccc(C)cc1)C(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(CC(=O)N1CCN(CC1)c1ccccc1)C(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(CC(=O)N1CCC(CC1)c1ccccc1)C(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(CC(=O)N(Cc1ccccc1)Cc1ccccc1)C(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(CC(=O)N(C)Cc1cccc(F)c1)C(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(CC(=O)N(C)Cc1ccccc1F)C(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(CC(=O)N(C)Cc1ccccc1)C(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CCCN(C(=O)CN(C)C(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O)c1ccccc1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(CC(=O)N1CCc2ccccc2C1)C(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(CC(=O)NC12CC3CC(CC(C3)C1)C2)C(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CC1Cc2ccccc2N1C(=O)CCCNC(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCCCC(=O)N1Cc2ccccc2C1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCCCC(=O)N1CCc2ccccc12,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CC1CCN(CC1)C(=O)CCCNC(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCCCC(=O)N1CCCCC1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCCCC(=O)N1CCN(CC1)c1ccccc1F,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(cc1)N1CCN(CC1)C(=O)CCCNC(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(CC(=O)N1CCN(CC1)c1ccc(F)cc1)C(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCCCC(=O)N1CCN(CC1)c1ccccc1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCCCC(=O)N1CCC(CC1)c1ccccc1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCCCC(=O)N(Cc1ccccc1)Cc1ccccc1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(Cc1cccc(F)c1)C(=O)CCCNC(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(Cc1ccccc1F)C(=O)CCCNC(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(Cc1ccccc1)C(=O)CCCNC(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CCCN(C(=O)CCCNC(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O)c1ccccc1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(C(=O)CCCNC(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O)c1ccccc1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCCCC(=O)N1CCc2ccccc2C1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCCCC(=O)NC12CC3CC(CC(C3)C1)C2,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCCC(=O)N1CCCc2ccccc12,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCCC(=O)N1Cc2ccccc2C1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCCC(=O)N1CCc2ccccc12,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CC1CCN(CC1)C(=O)CCNC(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCCC(=O)N1CCCCC1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCCC(=O)N1CCN(CC1)c1ccc(cc1)C(F)(F)F,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCCC(=O)N1CCN(CC1)c1ccc(F)cc1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
Cc1ccc(cc1)N1CCN(CC1)C(=O)CCNC(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCCC(=O)N1CCN(CC1)c1ccccc1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)N(C(C)C)C(=O)CCNC(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCCC(=O)N1CCC(CC1)c1ccccc1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(Cc1cccc(F)c1)C(=O)CCNC(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(Cc1ccccc1F)C(=O)CCNC(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(Cc1ccccc1)C(=O)CCNC(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CN(C(=O)CCNC(=O)c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O)c1ccccc1,VDR,not active,60000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCCCC(=O)N1CCN(CC1)c1ccc(F)cc1,VDR,not active,65000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)NCCC(=O)N1CCN(CC1)c1ccccc1F,VDR,not active,66000,IC50,10.1016/j.bmcl.2012.12.055, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ccccc2c1C(Nc1ccc(Cl)cc1)c1nccn1C,VDR,not active,66800,IC50,10.1021/ml400462j, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1CCOCC(O)C(O)COCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)C(C)(C)NC1=O)C(N)=O,VDR,not active,67000,IC50,10.1016/j.bmc.2015.01.007, not Ki or Kd; not used in NCI fingerprint analysis
Cn1cc(C(Nc2ccccc2)c2ccccc2Cl)c2ccccc12,VDR,not active,70000,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ccccc2c1C(Sc1ccccc1)c1ccccc1Cl,VDR,not active,70000,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
Cc1[nH]c2ccccc2c1C(c1c(C)[nH]c2ccccc12)c1ccccc1Cl,VDR,not active,75000,IC50,10.1021/ml400462j, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccccc1-c1nc(C)c(COc2ccc(CCC(O)=O)cc2)o1,VDR,not active,80000,IC50,10.1016/j.bmcl.2017.12.041, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(c1)-c1nc(C)c(COc2ccc(cc2)C(O)=O)o1,VDR,not active,80000,IC50,10.1016/j.bmcl.2017.12.041, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccccc1-c1nc(C)c(COc2ccc(CC(O)=O)cc2)o1,VDR,not active,80000,IC50,10.1016/j.bmcl.2017.12.041, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccccc1-c1nc(C)c(COc2ccccc2C(O)=O)o1,VDR,not active,80000,IC50,10.1016/j.bmcl.2017.12.041, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccccc1-c1nc(C)c(COc2ccc(cc2)C(O)=O)o1,VDR,not active,80000,IC50,10.1016/j.bmcl.2017.12.041, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccccc1-c1nc(C)c(COc2cccc(c2)C(O)=O)o1,VDR,not active,100000,IC50,10.1016/j.bmcl.2017.12.041, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CC(O)=O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,not active,100000,IC50,10.1016/j.ejmech.2016.01.002, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C,VDR,not active,150000,IC50,10.1016/j.ejmech.2016.01.002, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCC(=O)O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C,VDR,not active,150000,IC50,10.1016/j.ejmech.2016.01.002, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1CCOCCCCOCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)C(C)(C)NC1=O)C(O)=O,VDR,not active,220000,IC50,10.1016/j.bmcl.2013.06.002, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1COCCCCOC[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)C(C)(C)NC1=O)C(O)=O,VDR,not active,430000,IC50,10.1016/j.bmcl.2013.06.002, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCOCC=C)C(=O)NC(C)(C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCOCC=C)C(O)=O,VDR,not active,500000,IC50,10.1016/j.bmc.2015.01.007, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1CCOCCCCOC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)C(C)(C)NC1=O)C(O)=O,VDR,not active,520000,IC50,10.1016/j.bmcl.2013.06.002, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]1COCCCCOC[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)C(C)(C)NC1=O)C(O)=O,VDR,not active,600000,IC50,10.1016/j.bmcl.2013.06.002, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1COCCCCOC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)C(C)(C)NC1=O)C(O)=O,VDR,not active,610000,IC50,10.1016/j.bmcl.2013.06.002, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]1COCCCCOC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)C(C)(C)NC1=O)C(O)=O,VDR,not active,610000,IC50,10.1016/j.bmcl.2013.06.002, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@@H](CC(C)(C)O)CC[C@]4(C)[C@H]3CC[C@]12C,VDR,active,3.6,EC50,PMID:33369416, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](CC(C)(C)O)CC[C@]4(C)[C@H]3CC[C@]12C,VDR,active,5.3,EC50,PMID:33369416, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1[C@@H](O)[C@H]2[C@@H]3CC[C@H]([C@H](C)CCC(O)=O)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]2(C)CC[C@@H](O)C[C@@H]12,VDR,not active,100000,EC50,PMID:27652492, not Ki or Kd; not used in NCI fingerprint analysis
CCN(CC)CCNC(=O)c1ccc(n1CC)C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1,VDR,active,91,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)c1ccc(OC(=O)c2ccc(n2CC)C(CC)(CC)c2ccc(OCC(=O)C(C)(C)C)c(C)c2)cc1,VDR,not active,45600,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1)C(=O)Nc1ccc(OC(F)(F)F)cc1,VDR,not active,50000,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1)C(=O)Nc1cccc(c1)C(F)(F)F,VDR,not active,50000,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1)C(=O)Oc1ccc(CCO)cc1,VDR,not active,5100,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1)C(=O)OCc1ccc(F)cc1,VDR,not active,50000,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1)C(=O)NCCCN1CCOCC1,VDR,active,18,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1)C(=O)NCCN,VDR,active,10,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1)C(=O)N(C)c1ccccc1,VDR,not active,6400,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1)C(=O)OC(C)C#C,VDR,medium,200,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1)C(=O)OCCC#C,VDR,not active,1030,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H](C)[C@H](NC(=O)c1ccc(n1CC)C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1)C(O)=O,VDR,active,10,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1)C(=O)N(C)CC(O)=O,VDR,medium,740,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1)C(=O)Nc1ccc(OC(F)(F)F)cc1,VDR,not active,50000,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)CN(C)C(=O)c1ccc(n1CC)C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1,VDR,not active,50000,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCN(CC)CCCNC(=O)c1ccc(n1CC)C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1,VDR,active,22,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1)C(=O)NCC(OC)OC,VDR,medium,130,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1)C(=O)N(C)CCC#N,VDR,not active,9800,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1)C(=O)N(C)c1ccccc1,VDR,not active,18500,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)CN(C)C(=O)c1ccc(n1CC)C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1,VDR,medium,210,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1)C(=O)NCCCN(C)C,VDR,active,37,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1)C(=O)OCc1ccccn1,VDR,not active,50000,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1)C(=O)NCCN(C)C,VDR,active,77,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1)C(=O)OC(C)CCO,VDR,medium,380,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1)C(=O)NCCBr,VDR,not active,1900,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1)C(=O)NCCCN(C)C,VDR,active,96,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H](C)[C@H](NC(=O)c1ccc(n1CC)C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1)C(=O)OC,VDR,active,26,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1)C(=O)OCc1ccc(F)cc1,VDR,not active,9500,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1)C(=O)N(C)CC=C,VDR,not active,3950,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H](C)[C@H](NC(=O)c1ccc(n1CC)C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1)C(=O)OC,VDR,medium,590,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1)C(=O)NCC#C,VDR,not active,2200,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1)C(=O)NCCN,VDR,medium,120,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1)C(=O)N(CCC#N)CCC#N,VDR,medium,870,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1)C(=O)NCCN(C)C,VDR,active,14,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H](C)[C@H](NC(=O)c1ccc(n1CC)C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1)C(O)=O,VDR,active,2.3,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCN(CC)CCCNC(=O)c1ccc(n1CC)C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1,VDR,active,66,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1)C(=O)NCCBr,VDR,medium,130,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1)C(=O)N(C)CC(O)=O,VDR,not active,1390,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1)C(=O)Nc1cccc(c1)C(F)(F)F,VDR,not active,50000,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1)C(=O)Oc1ccc(CC(=O)OC)cc1,VDR,not active,2320,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)c1ccc(OC(=O)c2ccc(n2CC)C(CC)(CC)c2ccc(OCC(O)C(C)(C)C)c(C)c2)cc1,VDR,not active,50000,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1ccc(OCC(=O)C(C)(C)C)c(C)c1,VDR,medium,590,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1)C(=O)OC(C)C#C,VDR,medium,210,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1)C(=O)OCCC#C,VDR,not active,28800,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1)C(=O)OCc1ccccn1,VDR,not active,50000,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)CC(C)OC(=O)c1ccc(n1CC)C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1,VDR,not active,50000,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCOc1ccc(NC(=O)c2ccc(n2CC)C(CC)(CC)c2ccc(OCC(=O)C(C)(C)C)c(C)c2)cc1,VDR,not active,50000,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1)C(=O)N(C)CCC#N,VDR,not active,1960,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OCCC(C)(C)O)c(C)c1)c1ccc(OCC(CO)CO)c(C)c1,VDR,active,77,EC50,10.1016/j.bmc.2018.11.008, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OCCC(C)(C)O)c(C)c1)c1ccc(OC[C@@H](O)CO)c(C)c1,VDR,active,42,EC50,10.1016/j.bmc.2018.11.008, not Ki or Kd; not used in NCI fingerprint analysis
CCC(O)(CC)COc1ccc(cc1C)C(CC)(CC)c1ccc(OC(CO)CO)c(C)c1,VDR,active,17,EC50,10.1016/j.bmc.2018.11.008, not Ki or Kd; not used in NCI fingerprint analysis
CCC(O)(CC)COc1ccc(cc1C)C(CC)(CC)c1ccc(OC[C@@H](O)CO)c(C)c1,VDR,active,18,EC50,10.1016/j.bmc.2018.11.008, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OC[C@@H](O)CO)c(C)c1)c1ccc(OCC(C)(C)O)c(C)c1,VDR,medium,163,EC50,10.1016/j.bmc.2018.11.008, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OC[C@@H](O)CO)c(C)c1)c1ccc(OC[C@H](O)C(C)(C)C)c(C)c1,VDR,active,0.04,EC50,10.1016/j.bmc.2018.11.008, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OCC(CO)CO)c(C)c1)c1ccc(OCC(C)(C)O)c(C)c1,VDR,active,77,EC50,10.1016/j.bmc.2018.11.008, not Ki or Kd; not used in NCI fingerprint analysis
CCC(O)(CC)COc1ccc(cc1C)C(CC)(CC)c1ccc(OCC(CO)CO)c(C)c1,VDR,active,9.3,EC50,10.1016/j.bmc.2018.11.008, not Ki or Kd; not used in NCI fingerprint analysis
CCCCC(=O)c1cc(cn1CC)C(CC)(CC)c1ccc(C#CC(O)(CC)CC)c(C)c1,VDR,active,50,EC50,10.1016/j.bmcl.2017.01.084, not Ki or Kd; not used in NCI fingerprint analysis
CCn1cc(cc1C(=O)N[C@@H](C(C)C)C(O)=O)C(CC)(CC)c1ccc(C#CC(O)(CC)CC)c(C)c1,VDR,active,13,EC50,10.1016/j.bmcl.2017.01.084, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)CCC[C@@H]1C[C@@H]2C[C@H]3[C@@H]4CCc5cc(O)ccc5[C@H]4CC[C@]3(C)[C@]12O,VDR,not active,4100,EC50,10.1016/j.bmcl.2017.05.089, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)CCC[C@@H]1C[C@@]11CC[C@H]2[C@@H]3CCc4cc(O)ccc4[C@H]3CC[C@]12C,VDR,not active,3700,EC50,10.1016/j.bmcl.2017.05.089, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2[C@@H]3CCc4cc(O)ccc4[C@H]3CC[C@]12C,VDR,medium,850,EC50,10.1016/j.bmcl.2017.05.089, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CCNC(=S)Nc1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(N)=O,VDR,medium,142,Kd,10.1021/acs.jmedchem.7b00732,Over 100 nM
CC[C@H](C)[C@@H]1NC(=O)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NCCC(=O)NC(=S)Nc2ccc3c(c2)C(=O)OC32c3ccc(O)cc3Oc3cc(O)ccc23)C(=O)NCC(NC(=O)[C@H](CC(C)C)NC1=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(N)=O,VDR,medium,197,Kd,10.1021/acs.jmedchem.7b00732,Over 100 nM
CC[C@H](C)[C@@H]1NC(=O)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCNC(=S)Nc2ccc3c(c2)C(=O)OC32c3ccc(O)cc3Oc3cc(O)ccc23)C(=O)NCC(NC(=O)C(CC(C)(C)C)NC1=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC(CC(C)(C)C)C(=O)NC(CC(C)(C)C)C(=O)N[C@@H](CCC(N)=O)C(N)=O,VDR,not active,2000,Kd,10.1021/acs.jmedchem.7b00732,Over 100 nM
CCn1c(ccc1C(CC)(CC)c1ccc(OCCC(O)(CC)CC)c(C)c1)C(=O)N(CCC#N)CCC#N,VDR,not active,10000,EC50,10.1021/acs.jmedchem.8b00106, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCCC(O)(CC)CC)c(C)c1)C(=O)N(C)CC=C,VDR,not active,10000,EC50,10.1021/acs.jmedchem.8b00106, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCCC(O)(CC)CC)c(C)c1)C(=O)OCCC#C,VDR,not active,6033,EC50,10.1021/acs.jmedchem.8b00106, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCCC(O)(CC)CC)c(C)c1)C(=O)Oc1ccc(CC(=O)OC)cc1,VDR,not active,10000,EC50,10.1021/acs.jmedchem.8b00106, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCCC(O)(CC)CC)c(C)c1)C(=O)Nc1ccc(OC(F)(F)F)cc1,VDR,not active,10000,EC50,10.1021/acs.jmedchem.8b00106, not Ki or Kd; not used in NCI fingerprint analysis
CCC(C)C(NC(=O)c1ccc(n1CC)C(CC)(CC)c1ccc(OCCC(O)(CC)CC)c(C)c1)C(=O)OC,VDR,not active,10000,EC50,10.1021/acs.jmedchem.8b00106, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)C(CC(=O)OC)NC(=O)c1ccc(n1CC)C(CC)(CC)c1ccc(OCCC(O)(CC)CC)c(C)c1,VDR,active,21,EC50,10.1021/acs.jmedchem.8b00106, not Ki or Kd; not used in NCI fingerprint analysis
CCC(C)C(NC(=O)c1ccc(n1CC)C(CC)(CC)c1ccc(OCCC(O)(CC)CC)c(C)c1)C(O)=O,VDR,medium,860,EC50,10.1021/acs.jmedchem.8b00106, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCCC(O)(CC)CC)c(C)c1)C(=O)NC(C)C(O)=O,VDR,active,66,EC50,10.1021/acs.jmedchem.8b00106, not Ki or Kd; not used in NCI fingerprint analysis
CCC(C)C(CO)NC(=O)c1ccc(n1CC)C(CC)(CC)c1ccc(OCCC(O)(CC)CC)c(C)c1,VDR,medium,450,EC50,10.1021/acs.jmedchem.8b00106, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCCC(O)(CC)CC)c(C)c1)C(=O)N(C)CCO,VDR,active,53,EC50,10.1021/acs.jmedchem.8b00106, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCCC(O)(CC)CC)c(C)c1)C(=O)NC(C)CO,VDR,active,96,EC50,10.1021/acs.jmedchem.8b00106, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCCC(O)(CC)CC)c(C)c1)C(=O)NCCCN(C)C,VDR,active,5,EC50,10.1021/acs.jmedchem.8b00106, not Ki or Kd; not used in NCI fingerprint analysis
CCN(CC)CCNC(=O)c1ccc(n1CC)C(CC)(CC)c1ccc(OCCC(O)(CC)CC)c(C)c1,VDR,active,2.3,EC50,10.1021/acs.jmedchem.8b00106, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCCC(O)(CC)CC)c(C)c1)C(=O)NCC#N,VDR,not active,1080,EC50,10.1021/acs.jmedchem.8b00106, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCCC(O)(CC)CC)c(C)c1)C(=O)NCCCN1CCOCC1,VDR,medium,238,EC50,10.1021/acs.jmedchem.8b00106, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCCC(O)(CC)CC)c(C)c1)C(=O)NCCN(C)C,VDR,active,82,EC50,10.1021/acs.jmedchem.8b00106, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCCC(O)(CC)CC)c(C)c1)C(=O)NCCN,VDR,medium,156,EC50,10.1021/acs.jmedchem.8b00106, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCCC(O)(CC)CC)c(C)c1)C(=O)OC(C)C#C,VDR,not active,2653,EC50,10.1021/acs.jmedchem.8b00106, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCCC(O)(CC)CC)c(C)c1)C(=O)Nc1cccc(c1)C(F)(F)F,VDR,not active,5900,EC50,10.1021/acs.jmedchem.8b00106, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)CN(C)C(=O)c1ccc(n1CC)C(CC)(CC)c1ccc(OCCC(O)(CC)CC)c(C)c1,VDR,medium,520,EC50,10.1021/acs.jmedchem.8b00106, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCCC(O)(CC)CC)c(C)c1)C(=O)NC(CC(O)=O)C(=O)OC,VDR,active,26,EC50,10.1021/acs.jmedchem.8b00106, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCCC(O)(CC)CC)c(C)c1)C(=O)NC(CO)CCO,VDR,not active,2494,EC50,10.1021/acs.jmedchem.8b00106, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1)C(=O)NC(C)CO,VDR,active,8.5,EC50,10.1021/acs.jmedchem.8b00106, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CC#C[C@@H](O)C12CC3CC(CC(C3)C1)C2)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,0.14,EC50,10.1021/acs.jmedchem.8b00427, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CC#C[C@H](O)C12CC3CC(CC(C3)C1)C2)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,3.2,EC50,10.1021/acs.jmedchem.8b00427, not Ki or Kd; not used in NCI fingerprint analysis
CCc1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccc(OCC2CCOCC2)c(c1)[S@@](C)(=N)=O,VDR,not active,10000,Kd,10.1016/j.bmcl.2018.03.041,Over 100 nM
CC\C(=C/C=C1/C[C@@H](O)C[C@H](O)C1=C)c1cccc(CCCCCC(C)(C)O)c1,VDR,active,5.6,EC50,10.1021/acs.jmedchem.8b00337, not Ki or Kd; not used in NCI fingerprint analysis
CCCC\C(=C/C=C1/C[C@@H](O)C[C@H](O)C1=C)c1cccc(CCCCCC(C)(C)O)c1,VDR,active,9,EC50,10.1021/acs.jmedchem.8b00337, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCCC\C(=C/C=C1/C[C@@H](O)C[C@H](O)C1=C)c1cccc(CCCCCC(C)(C)O)c1,VDR,active,2.9,EC50,10.1021/acs.jmedchem.8b00337, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCC\C(=C/C=C1/C[C@@H](O)C[C@H](O)C1=C)c1cccc(CCCCCC(C)(C)O)c1,VDR,active,1,EC50,10.1021/acs.jmedchem.8b00337, not Ki or Kd; not used in NCI fingerprint analysis
CCC\C(=C/C=C1/C[C@@H](O)C[C@H](O)C1=C)c1cccc(CCCCCC(C)(C)O)c1,VDR,active,8.6,EC50,10.1021/acs.jmedchem.8b00337, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCCC(O)(CC)CC)c(C)c1)C(=O)N(C)CC(O)=O,VDR,active,89,EC50,10.1021/acs.jmedchem.8b00106, not Ki or Kd; not used in NCI fingerprint analysis
CCN(CC)CCCNC(=O)c1ccc(n1CC)C(CC)(CC)c1ccc(OCCC(O)(CC)CC)c(C)c1,VDR,active,11,EC50,10.1021/acs.jmedchem.8b00106, not Ki or Kd; not used in NCI fingerprint analysis
CCN(CC)CCNC(=O)c1ccc(n1CC)C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1,VDR,medium,110,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1)C(=O)N(C)CC=C,VDR,not active,21600,EC50,10.1016/j.ejmech.2015.10.042, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OC[C@H](O)CO)c(C)c1)c1ccc(OC[C@@H](O)C(C)(C)C)c(C)c1,VDR,active,83.2,EC50,10.1016/j.bmcl.2007.11.007, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OC[C@H](O)CO)c(C)c1)c1ccc(OC[C@H](O)C(C)(C)C)c(C)c1,VDR,active,16.8,EC50,10.1016/j.bmcl.2007.11.007, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OC[C@@H](O)CO)c(C)c1)c1ccc(OC[C@@H](O)C(C)(C)C)c(C)c1,VDR,active,9.9,EC50,10.1016/j.bmcl.2007.11.007, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H](CCCCO)C1CCC2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,0.3,Ki,10.1016/j.bioorg.2013.01.001,Below 1 nM
CCCC[C@@H](C)C1CCC2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,0.3,Ki,10.1016/j.bioorg.2013.01.001,Below 1 nM
CCCC[C@H](C)C1CCC2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,0.3,Ki,10.1016/j.bioorg.2013.01.001,Below 1 nM
O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1ccc[nH]1,VDR,active,0.31,Ki,US9550741,Below 1 nM
Cc1ccsc1C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1,VDR,active,0.37,Ki,US9550741,Below 1 nM
CCOC(=O)N[C@@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1,VDR,active,0.46,Ki,US9550741,Below 1 nM
CC(CCCC(C)(C)O)C1CCC2CC(CCC12C)\C=C\C=C1\C[C@@H](C)C[C@H](C)C1=C,VDR,active,0.5,Ki,10.1016/S1074-5521(99)80072-6,Below 1 nM
O=S(=O)(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1cc[nH]c1,VDR,active,0.57,Ki,US9550741,Below 1 nM
O=C(NCc1ccccc1)N[C@@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1,VDR,active,0.67,Ki,US9550741,Below 1 nM
O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)Oc1ccccc1,VDR,active,0.74,Ki,US9550741,Below 1 nM
O=C(N[C@@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1ccc[nH]1,VDR,active,0.84,Ki,US9550741,Below 1 nM
Cc1ccc2sc(cc2c1)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1,VDR,active,0.85,Ki,US9550741,Below 1 nM
O=S(=O)(N[C@@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1cc2ccccc2[nH]1,VDR,active,0.92,Ki,US9550741,Below 1 nM
O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)OCc1cccs1,VDR,active,0.95,Ki,US9550741,Below 1 nM
C[C@H](CCCCO)C1CCC2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(C)[C@H](O)C1,VDR,active,1,Ki,10.1016/j.bioorg.2013.01.001,1 nM to 10 nM
Brc1ccsc1C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1,VDR,active,1.02,Ki,US9550741,1 nM to 10 nM
O=S(=O)(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1cc2ccccc2s1,VDR,active,1.03,Ki,US9550741,1 nM to 10 nM
O=C(N[C@@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)OCc1ccccc1,VDR,active,1.03,Ki,US9550741,1 nM to 10 nM
O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)Nc1ccco1,VDR,active,1.04,Ki,US9550741,1 nM to 10 nM
O=C(N[C@@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1cc2ccccc2o1,VDR,active,1.04,Ki,US9550741,1 nM to 10 nM
COc1cccc(OC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3nsc4ccccc34)CC2)c1,VDR,active,1.05,Ki,US9550741,1 nM to 10 nM
CCc1c(sc2ccccc12)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1,VDR,active,1.42,Ki,US9550741,1 nM to 10 nM
O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)Nc1ccccc1,VDR,active,1.42,Ki,US9550741,1 nM to 10 nM
Cc1ccc([nH]1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1,VDR,active,1.43,Ki,US9550741,1 nM to 10 nM
Cc1ccc(o1)S(=O)(=O)N[C@@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1,VDR,active,1.44,Ki,US9550741,1 nM to 10 nM
O=S(=O)(N[C@@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1cc2ccccc2s1,VDR,active,1.7,Ki,US9550741,1 nM to 10 nM
Cc1ccc(o1)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1,VDR,active,1.73,Ki,US9550741,1 nM to 10 nM
O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)OC1CC1,VDR,active,1.81,Ki,US9550741,1 nM to 10 nM
C[C@H](C[C@H]1CC(=C)C(=O)O1)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,1,EC50,10.1016/j.bmc.2007.09.017, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](C[C@@H]1CC(=C)C(=O)O1)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,medium,200,EC50,10.1016/j.bmc.2007.09.017, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H](C[C@H]1CC(=C)C(=O)O1)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,15,EC50,10.1016/j.bmc.2007.09.017, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H](C[C@@H]1CC(=C)C(=O)O1)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,6,EC50,10.1016/j.bmc.2007.09.017, not Ki or Kd; not used in NCI fingerprint analysis
CCCCOC(=O)C1(CC1)[C@H](O)\C=C\[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,0.4,EC50,10.1021/jm0310582, not Ki or Kd; not used in NCI fingerprint analysis
CCOC(=O)\C=C\C1(CC1)[C@H](O)\C=C\[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,0.35,EC50,10.1021/jm0310582, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OC[C@@H](O)CO)c(C)c1)c1ccc(OCC(=O)C(C)(C)CCCc2ccccc2)c(C)c1,VDR,not active,30000,EC50,10.1016/j.bmcl.2010.09.011, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OC[C@@H](O)CO)c(C)c1)c1ccc(OCC(=O)C(C)(C)CCCCc2ccccc2)c(C)c1,VDR,not active,30000,EC50,10.1016/j.bmcl.2010.09.011, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OC[C@@H](O)CO)c(C)c1)c1ccc(OCC(=O)C23CC4CC(CC(C4)C2)C3)c(C)c1,VDR,not active,30000,EC50,10.1016/j.bmcl.2010.09.011, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OC[C@@H](O)CO)c(C)c1)c1ccc(OCC(=O)C(C)(C)Cc2ccc3ccccc3c2)c(C)c1,VDR,not active,30000,EC50,10.1016/j.bmcl.2010.09.011, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OC[C@@H](O)CO)c(C)c1)c1ccc(OCC(O)C(C)(C)Cc2ccccc2)c(C)c1,VDR,not active,11000,EC50,10.1016/j.bmcl.2010.09.011, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OC[C@@H](O)CO)c(C)c1)c1ccc(OCC(O)C(C)(C)CCc2ccccc2)c(C)c1,VDR,not active,7100,EC50,10.1016/j.bmcl.2010.09.011, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OC[C@@H](O)CO)c(C)c1)c1ccc(OCC(O)C(C)(C)CCCc2ccccc2)c(C)c1,VDR,not active,3600,EC50,10.1016/j.bmcl.2010.09.011, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OC[C@@H](O)CO)c(C)c1)c1ccc(OCC(O)C(C)(C)CCCCc2ccccc2)c(C)c1,VDR,not active,30000,EC50,10.1016/j.bmcl.2010.09.011, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OC[C@@H](O)CO)c(C)c1)c1ccc(OCC(O)C23CC4CC(CC(C4)C2)C3)c(C)c1,VDR,not active,22000,EC50,10.1016/j.bmcl.2010.09.011, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OC[C@@H](O)CO)c(C)c1)c1ccc(OCC(O)C(C)(C)Cc2ccc3ccccc3c2)c(C)c1,VDR,not active,30000,EC50,10.1016/j.bmcl.2010.09.011, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OC[C@@H](O)CO)c(C)c1)c1ccc(O[C@@H]2CN(Cc3ccccc3)C[C@@H]2O)c(C)c1,VDR,not active,30000,EC50,10.1016/j.bmcl.2010.09.011, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OC[C@@H](O)CO)c(C)c1)c1ccc(O[C@@H]2CN(C[C@@H]2O)C(=O)OCc2ccccc2)c(C)c1,VDR,not active,30000,EC50,10.1016/j.bmcl.2010.09.011, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OCC(O)CO)c(C)c1)c1ccc(OCC(=O)C(C)(C)C)c(C)c1,VDR,active,90,EC50,10.1016/j.bmcl.2010.09.011, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OC[C@@H](O)CO)c(C)c1)c1ccc(OCC(=O)C(C)(C)Cc2ccccc2)c(C)c1,VDR,not active,21000,EC50,10.1016/j.bmcl.2010.09.011, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OC[C@@H](O)CO)c(C)c1)c1ccc(OCC(=O)C(C)(C)CCc2ccccc2)c(C)c1,VDR,not active,23000,EC50,10.1016/j.bmcl.2010.09.011, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(C#CC(O)(CC)CC)c(C)c1)C(=O)NCCCO,VDR,medium,137,EC50,10.1016/j.bmcl.2017.01.084, not Ki or Kd; not used in NCI fingerprint analysis
CCn1cc(cc1C(=O)N[C@@H](C)CO)C(CC)(CC)c1ccc(C#CC(O)(CC)CC)c(C)c1,VDR,active,7.3,EC50,10.1016/j.bmcl.2017.01.084, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(C#CC(O)(CC)CC)c(C)c1)C(=O)NCCC(=O)OC,VDR,active,50,EC50,10.1016/j.bmcl.2017.01.084, not Ki or Kd; not used in NCI fingerprint analysis
CCN(CC)CCCNC(=O)c1ccc(n1CC)C(CC)(CC)c1ccc(C#CC(O)(CC)CC)c(C)c1,VDR,active,69,EC50,10.1016/j.bmcl.2017.01.084, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(C#CC(O)(CC)CC)c(C)c1)C(=O)NCc1ccc(OC)cc1,VDR,active,50,EC50,10.1016/j.bmcl.2017.01.084, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(C#CC(O)(CC)CC)c(C)c1)C(=O)OCCC#C,VDR,active,50,EC50,10.1016/j.bmcl.2017.01.084, not Ki or Kd; not used in NCI fingerprint analysis
CCCCC(=O)c1ccc(n1CC)C(CC)(CC)c1ccc(C#CC(O)(CC)CC)c(C)c1,VDR,active,50,EC50,10.1016/j.bmcl.2017.01.084, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(C#CC(O)(CC)CC)c(C)c1)C(=O)NCC(O)=O,VDR,active,9.4,EC50,10.1016/j.bmcl.2017.01.084, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(C#CC(O)(CC)CC)c(C)c1)C(=O)N[C@@H](C(C)C)C(O)=O,VDR,active,18,EC50,10.1016/j.bmcl.2017.01.084, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(C#CC(O)(CC)CC)c(C)c1)C(=O)NCCC(O)=O,VDR,medium,293,EC50,10.1016/j.bmcl.2017.01.084, not Ki or Kd; not used in NCI fingerprint analysis
CCn1cc(cc1C(=O)NCC(=O)OC)C(CC)(CC)c1ccc(C#CC(O)(CC)CC)c(C)c1,VDR,medium,288,EC50,10.1016/j.bmcl.2017.01.084, not Ki or Kd; not used in NCI fingerprint analysis
CCn1cc(cc1C(=O)NCCN(C)C)C(CC)(CC)c1ccc(C#CC(O)(CC)CC)c(C)c1,VDR,active,19,EC50,10.1016/j.bmcl.2017.01.084, not Ki or Kd; not used in NCI fingerprint analysis
CCn1cc(cc1C(=O)NCCCN(C)C)C(CC)(CC)c1ccc(C#CC(O)(CC)CC)c(C)c1,VDR,medium,142,EC50,10.1016/j.bmcl.2017.01.084, not Ki or Kd; not used in NCI fingerprint analysis
CCn1cc(cc1C(=O)OCCO)C(CC)(CC)c1ccc(C#CC(O)(CC)CC)c(C)c1,VDR,active,13,EC50,10.1016/j.bmcl.2017.01.084, not Ki or Kd; not used in NCI fingerprint analysis
CCn1cc(cc1C(=O)NCC(O)=O)C(CC)(CC)c1ccc(C#CC(O)(CC)CC)c(C)c1,VDR,active,54,EC50,10.1016/j.bmcl.2017.01.084, not Ki or Kd; not used in NCI fingerprint analysis
CCn1cc(cc1C(=O)NCCC(O)=O)C(CC)(CC)c1ccc(C#CC(O)(CC)CC)c(C)c1,VDR,active,50,EC50,10.1016/j.bmcl.2017.01.084, not Ki or Kd; not used in NCI fingerprint analysis
CCn1cc(cc1C(=O)N[C@H](C(C)C)C(O)=O)C(CC)(CC)c1ccc(C#CC(O)(CC)CC)c(C)c1,VDR,active,68,EC50,10.1016/j.bmcl.2017.01.084, not Ki or Kd; not used in NCI fingerprint analysis
CC(CCCC(C)(C)O)C1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,8.1,EC50,10.1016/j.bmcl.2017.01.084, not Ki or Kd; not used in NCI fingerprint analysis
CCN(CC)CCNC(=O)c1ccc(n1CC)C(CC)(CC)c1ccc(C#CC(O)(CC)CC)c(C)c1,VDR,active,10,EC50,10.1016/j.bmcl.2017.01.084, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(C#CC(O)(CC)CC)c(C)c1)C(=O)On1nnc2ccccc12,VDR,active,50,EC50,10.1016/j.bmcl.2017.01.084, not Ki or Kd; not used in NCI fingerprint analysis
CCN(CC)CCNC(=O)c1cc(cn1CC)C(CC)(CC)c1ccc(C#CC(O)(CC)CC)c(C)c1,VDR,active,7,EC50,10.1016/j.bmcl.2017.01.084, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H](O)C[C@](C)(O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,medium,175,EC50,10.1021/acs.jmedchem.6b00182, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@@H](O)C[C@](C)(O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,medium,117,EC50,10.1021/acs.jmedchem.6b00182, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@@H](O)C[C@](C)(O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)CCC1=C,VDR,medium,653,EC50,10.1021/acs.jmedchem.6b00182, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H](\C=C\C[C@@H](O)CC12CC3CC(CC(C3)C1)C2)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,24,EC50,10.1021/jm8004477, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H](\C=C\C[C@@H](O)C12CC3CC(CC(C3)C1)C2)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,1,EC50,10.1021/jm8004477, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](\C=C\[C@@H](O)C12CC3CC(CC(C3)C1)C2)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,0.02,EC50,10.1021/jm8004477, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1onc(c1COc1ccc(N(C)Cc2ccc(cc2)C(O)=O)c(n1)C(F)(F)F)-c1c(Cl)cccc1Cl,VDR,not active,10000,EC50,10.1016/j.bmcl.2010.06.084, not Ki or Kd; not used in NCI fingerprint analysis
CN(Cc1cccc(c1)C(O)=O)c1ccc(OCc2c(onc2-c2c(Cl)cccc2Cl)C2CC2)nc1C(F)(F)F,VDR,not active,10000,EC50,10.1016/j.bmcl.2010.06.084, not Ki or Kd; not used in NCI fingerprint analysis
CN(Cc1ccc(cc1)C(O)=O)c1ccc(OCc2c(onc2-c2c(Cl)cccc2Cl)C2CC2)nc1C(F)(F)F,VDR,not active,10000,EC50,10.1016/j.bmcl.2010.06.084, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OC[C@H](O)C(C)(C)C)c(C)c1)c1ccc(OC(CCO)CCO)c(C)c1,VDR,active,19.4,EC50,10.1016/j.bmcl.2011.08.047, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OCC(CO)CO)c(C)c1)c1ccc(OC[C@H](O)C(C)(C)C)c(C)c1,VDR,active,1.11,EC50,10.1016/j.bmcl.2011.08.047, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OC[C@H](O)C(C)(C)C)c(C)c1)c1ccc(O[C@@H](CO)[C@@H](O)CO)c(C)c1,VDR,active,0.92,EC50,10.1016/j.bmcl.2011.08.047, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OC[C@H](O)C(C)(C)C)c(C)c1)c1ccc(O[C@H](CO)[C@H](O)CO)c(C)c1,VDR,active,1.25,EC50,10.1016/j.bmcl.2011.08.047, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OC[C@H](O)C(C)(C)C)c(C)c1)c1ccc(O[C@@H](CO)CCO)c(C)c1,VDR,active,0.06,EC50,10.1016/j.bmcl.2011.08.047, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OC[C@H](O)C(C)(C)C)c(C)c1)c1ccc(O[C@H](CO)CCO)c(C)c1,VDR,active,1.29,EC50,10.1016/j.bmcl.2011.08.047, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](\C=C\[C@@H](O)C1CC1)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,0.31,Kd,10.1021/jm0000214,Below 1 nM
C[C@@H](COc1ccc(cc1)C(C)(C)O)C1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,0.073,Kd,10.1021/jm0000214,Below 1 nM
C[C@@H](CSc1ccc(cc1)C(C)(C)O)C1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,0.089,Kd,10.1021/jm0000214,Below 1 nM
CC\C(=C/C=C/C(O)(C(F)(F)F)C(F)(F)F)c1cccc(OCc2ccc(CO)c(CO)c2)c1,VDR,active,5,EC50,10.1021/jm300858s, not Ki or Kd; not used in NCI fingerprint analysis
CC\C(=C/C=C/C(O)(CC)CC)c1cccc(OCc2ccc(CO)c(CO)c2)c1,VDR,active,49,EC50,10.1021/jm300858s, not Ki or Kd; not used in NCI fingerprint analysis
CC\C(=C/C=C/C(O)(C(F)(F)F)C(F)(F)F)c1cccc(CCc2ccc(CO)c(CO)c2)c1,VDR,active,2.8,EC50,10.1021/jm300858s, not Ki or Kd; not used in NCI fingerprint analysis
CCCc1cc(ccc1-c1cc(OCc2ccc(CO)c(CO)c2)ccc1CC)C(O)(CC)CC,VDR,active,2.2,EC50,10.1021/jm300858s, not Ki or Kd; not used in NCI fingerprint analysis
CCCc1cc(ccc1-c1cc(CCc2ccc(CO)c(CO)c2)ccc1C)C(O)(CC)CC,VDR,active,0.5,EC50,10.1021/jm300858s, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCCO)[C@H]1CC[C@H]2\C(CC[C@@H](CCCCCCC(C)(C)O)[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,5.74,EC50,10.1021/jm3008272, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCO)[C@H]1CC[C@H]2\C(CC[C@@H](CCCCCCC(C)(C)O)[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,9.04,EC50,10.1021/jm3008272, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CO)[C@H]1CC[C@H]2\C(CC[C@@H](CCCCCCC(C)(C)O)[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,8.19,EC50,10.1021/jm3008272, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCC(C)(C)O)[C@H](C)[C@H]1CCC2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,0.003,EC50,10.1021/jm060889f, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](CCC(C)(C)O)[C@H](C)[C@H]1CCC2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,0.002,EC50,10.1021/jm060889f, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@H](CCC(C)(C)O)[C@H](C)[C@H]1CCC2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,0.2,EC50,10.1021/jm060889f, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)[C@H](O)CC[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,7.1,EC50,10.1016/j.ejmech.2013.09.015, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1)C(=O)N[C@@H](C)C(O)=O,VDR,active,4.1,EC50,10.1016/j.ejmech.2013.09.015, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1)C(=O)NCCC(O)=O,VDR,not active,33220,EC50,10.1016/j.ejmech.2013.09.015, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(C(=O)NCCC(O)=O)n1C)c1ccc(OCC(O)C(C)(C)C)c(C)c1,VDR,not active,1600,EC50,10.1016/j.ejmech.2013.09.015, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(C(=O)NCC(O)=O)n1C)c1ccc(OCC(O)C(C)(C)C)c(C)c1,VDR,not active,4950,EC50,10.1016/j.ejmech.2013.09.015, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(C(=O)N[C@@H](CC(O)=O)C(O)=O)n1C)c1ccc(OCC(=O)C(C)(C)C)c(C)c1,VDR,medium,410,EC50,10.1016/j.ejmech.2013.09.015, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(C(=O)N[C@@H](C)C(O)=O)n1C)c1ccc(OCC(=O)C(C)(C)C)c(C)c1,VDR,not active,2630,EC50,10.1016/j.ejmech.2013.09.015, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1)C(=O)N[C@H](CO)CCO,VDR,medium,110,EC50,10.1016/j.ejmech.2013.09.015, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1)C(=O)NCCO,VDR,not active,5640,EC50,10.1016/j.ejmech.2013.09.015, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(C(=O)N[C@H](CO)CCO)n1C)c1ccc(OCC(O)C(C)(C)C)c(C)c1,VDR,medium,200,EC50,10.1016/j.ejmech.2013.09.015, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(C(=O)N[C@@H](C)CO)n1C)c1ccc(OCC(O)C(C)(C)C)c(C)c1,VDR,medium,570,EC50,10.1016/j.ejmech.2013.09.015, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(C(=O)NCCCO)n1C)c1ccc(OCC(O)C(C)(C)C)c(C)c1,VDR,medium,150,EC50,10.1016/j.ejmech.2013.09.015, not Ki or Kd; not used in NCI fingerprint analysis
CCn1c(ccc1C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1)C(=O)NCC(=O)OC,VDR,not active,1830,EC50,10.1016/j.ejmech.2013.09.015, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(C(=O)NCCC(=O)OC)n1C)c1ccc(OCC(=O)C(C)(C)C)c(C)c1,VDR,medium,790,EC50,10.1016/j.ejmech.2013.09.015, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(C(=O)NCC(=O)OC)n1C)c1ccc(OCC(=O)C(C)(C)C)c(C)c1,VDR,active,23,EC50,10.1016/j.ejmech.2013.09.015, not Ki or Kd; not used in NCI fingerprint analysis
CN(C)C(=O)c1ccc2n(nc(Oc3c(Cl)cccc3C(F)(F)F)c2c1)-c1ccc(cc1)C(O)=O,VDR,not active,10000,Kd,10.1016/j.bmcl.2016.10.023,Over 100 nM
CC[Si](CC)(c1ccc(OCC2CO2)c(C)c1)c1ccc(OCC(=O)C(C)(C)C)c(C)c1,VDR,active,40,EC50,10.1016/j.bmc.2013.01.060, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(C=CC(=O)CC(=O)C=Cc2ccc(O)c(OC)c2)ccc1O,VDR,not active,20000,EC50,10.1016/j.bmc.2012.11.033, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCCOC(C)(C)[C@H](O)COc1ccc(cc1C)C(CC)(CC)c1ccc(OC[C@@H](O)CO)c(C)c1,VDR,not active,10000,EC50,10.1016/j.bmcl.2015.09.030, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OC[C@@H](O)CO)c(C)c1)c1ccc(OC[C@H](O)C(C)(C)OCCCCCCCCO)c(C)c1,VDR,not active,1200,EC50,10.1016/j.bmcl.2015.09.030, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)(c1ccc(OC[C@@H](O)CO)c(C)c1)c1ccc(OC[C@@H](O)C(C)(C)OCCCCCCCCO)c(C)c1,VDR,not active,3000,EC50,10.1016/j.bmcl.2015.09.030, not Ki or Kd; not used in NCI fingerprint analysis
C[C@]12CCC\C(=C/C=C3C[C@@H](O)C(=C)[C@H](O)C3)[C@@H]1CC[C@@H]2C#CC#C[C@H](O)C12CC3CC(CC(C3)C1)C2,VDR,active,7,EC50,10.1021/acs.jmedchem.5b00792, not Ki or Kd; not used in NCI fingerprint analysis
C[C@]12CCC\C(=C/C=C3C[C@@H](O)C(=C)[C@H](O)C3)[C@@H]1CC[C@@H]2C#CC#C[C@@H](O)C12CC3CC(CC(C3)C1)C2,VDR,active,1.5,EC50,10.1021/acs.jmedchem.5b00792, not Ki or Kd; not used in NCI fingerprint analysis
C[C@]12CCC\C(=C/C=C3C[C@@H](O)C(=C)[C@H](O)C3)[C@@H]1CC[C@@H]2C#CC#C[C@H](O)CC12CC3CC(CC(C3)C1)C2,VDR,active,30,EC50,10.1021/acs.jmedchem.5b00792, not Ki or Kd; not used in NCI fingerprint analysis
C[C@]12CCC\C(=C/C=C3C[C@@H](O)C(=C)[C@H](O)C3)[C@@H]1CC[C@@H]2C#CC#C[C@@H](O)CC12CC3CC(CC(C3)C1)C2,VDR,active,20,EC50,10.1021/acs.jmedchem.5b00792, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H]1C[C@H](C1)c1nnc([C@H]2CN(C[C@@H]2C(=O)Nc2ccc(C)cc2C)C(C)=O)n1C1CC1,VDR,not active,20000,EC50,10.1021/acsmedchemlett.5b00253, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)CCCC1(CC1)C1=CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,0.68,EC50,10.1021/jm801365a, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)(O)C(=O)CCC1(CC1)C1=CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,0.69,EC50,10.1021/jm801365a, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(c1)-c1nc(SC)c2ccccc2n1,VDR,not active,3000,EC50,10.1021/acs.jmedchem.5b01891, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(c1)-c1nc(OC)c2ccccc2n1,VDR,not active,1950,EC50,10.1021/acs.jmedchem.5b01891, not Ki or Kd; not used in NCI fingerprint analysis
COc1cccc(c1)-c1nc2ccccc2c(=S)[nH]1,VDR,medium,510,EC50,10.1021/acs.jmedchem.5b01891, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](OCCC(C)(C)O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,0.855,EC50,10.1021/acs.jmedchem.6b00182, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)[C@H](CCn2ccnc2)[C@H](O)C1=C,VDR,active,0.68,EC50,10.1021/ml400098w, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)[C@H](CCn2ccnn2)[C@H](O)C1=C,VDR,active,0.21,EC50,10.1021/ml400098w, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)[C@H](CCn2nccn2)[C@H](O)C1=C,VDR,active,0.044,EC50,10.1021/ml400098w, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)[C@H](CCn2cncn2)[C@H](O)C1=C,VDR,active,0.15,EC50,10.1021/ml400098w, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)[C@H](CCn2cnnn2)[C@H](O)C1=C,VDR,active,0.29,EC50,10.1021/ml400098w, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)[C@H](CCn2ncnn2)[C@H](O)C1=C,VDR,active,0.01,EC50,10.1021/ml400098w, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CC#C[C@H](O)C12CC3CC(CC(C3)C1)C2)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,6.6,EC50,10.1021/jm401989c, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CC#C[C@@H](O)CC12CC3CC(CC(C3)C1)C2)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,1.1,EC50,10.1021/jm401989c, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CC#C[C@H](O)CC12CC3CC(CC(C3)C1)C2)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,1.5,EC50,10.1021/jm401989c, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CC#C[C@@H](O)C12CC3CC(CC(C3)C1)C2)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,0.07,EC50,10.1021/jm401989c, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)CCC1=C,VDR,active,0.21,EC50,10.1016/j.bmcl.2014.09.053, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCCC(C)(C)O)C1CC[C@@]2(C)\C(CCC[C@]12C)=C/C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,0.18,EC50,10.1021/jm0310582, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCCC(C)(C)O)C1CCC2\C(CCCC12C)=C\C=C1C[C@@H](O)C(=CCF)[C@H](O)C1,VDR,active,2.2,EC50,10.1016/j.bmc.2006.10.069, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H](CCCC(C)(C)O)C1CCC2\C(CCCC12C)=C\C=C1C[C@@H](O)C(=CCF)[C@H](O)C1,VDR,active,1.1,EC50,10.1016/j.bmc.2006.10.069, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)[C@@H](O)CC[C@](C)(O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,medium,271,EC50,10.1021/acs.jmedchem.5b00881, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)[C@H](O)CC[C@](C)(O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,65,EC50,10.1021/acs.jmedchem.5b00881, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCCOC(C)(C)[C@@H](O)COc1ccc(cc1C)C(CC)(CC)c1ccc(OC[C@@H](O)CO)c(C)c1,VDR,not active,1500,EC50,10.1016/j.bmcl.2015.09.030, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc2oc(cc2c1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1,VDR,active,1.87,Ki,US9550741,1 nM to 10 nM
O=S(=O)(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1cc2cc(ccc2s1)[N+]#[C-],VDR,active,1.99,Ki,US9550741,1 nM to 10 nM
CCCC[C@@H](C)C1CCC2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(C)[C@H](O)C1,VDR,active,2,Ki,10.1016/j.bioorg.2013.01.001,1 nM to 10 nM
O=S(=O)(N[C@@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1cc2ccccc2o1,VDR,active,2.01,Ki,US9550741,1 nM to 10 nM
O=C(N[C@@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)Nc1ccccc1,VDR,active,2.05,Ki,US9550741,1 nM to 10 nM
COc1ccc2sc(cc2c1)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1,VDR,active,2.18,Ki,US9550741,1 nM to 10 nM
O=C(N[C@@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)Nc1ccco1,VDR,active,2.3,Ki,US9550741,1 nM to 10 nM
COc1cccc(NC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3nsc4ccccc34)CC2)c1,VDR,active,2.71,Ki,US9550741,1 nM to 10 nM
O=S(=O)(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1c[nH]c2ccccc12,VDR,active,2.76,Ki,US9550741,1 nM to 10 nM
CC(C)(C)c1ccoc1C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1,VDR,active,2.78,Ki,US9550741,1 nM to 10 nM
Clc1c(sc2ccccc12)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1,VDR,active,2.86,Ki,US9550741,1 nM to 10 nM
O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1ccc(o1)C#N,VDR,active,3.21,Ki,US9550741,1 nM to 10 nM
Clc1ccc2sc(cc2c1)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1,VDR,active,3.6,Ki,US9550741,1 nM to 10 nM
O=C(N[C@@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1cc2ccccc2s1,VDR,active,3.8,Ki,US9550741,1 nM to 10 nM
O=C(NCCc1ccccc1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1,VDR,active,3.81,Ki,US9550741,1 nM to 10 nM
[O-][N+](=O)c1ccc2[nH]c(cc2c1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1,VDR,active,4.03,Ki,US9550741,1 nM to 10 nM
[O-][N+](=O)c1cccc(NC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3nsc4ccccc34)CC2)c1,VDR,active,4.15,Ki,US9550741,1 nM to 10 nM
Clc1ccc(o1)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1,VDR,active,4.51,Ki,US9550741,1 nM to 10 nM
O=S(=O)(N[C@@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1ccco1,VDR,active,5.37,Ki,US9550741,1 nM to 10 nM
CN(C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1cccs1,VDR,active,5.8,Ki,US9550741,1 nM to 10 nM
O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)OCc1cc2ccccc2o1,VDR,active,6.53,Ki,US9550741,1 nM to 10 nM
CC(=O)c1ccc(o1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1,VDR,active,6.98,Ki,US9550741,1 nM to 10 nM
CC(C)(C)c1ccc(s1)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1,VDR,active,7.09,Ki,US9550741,1 nM to 10 nM
[O-][N+](=O)c1ccc(OC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3nsc4ccccc34)CC2)cc1,VDR,active,7.12,Ki,US9550741,1 nM to 10 nM
O=S(=O)(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1ccc(o1)[N+]#[C-],VDR,active,8.19,Ki,US9550741,1 nM to 10 nM
CCCCN(C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1ccccc1,VDR,active,8.22,Ki,US9550741,1 nM to 10 nM
Cc1ccccc1OC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1,VDR,active,8.49,Ki,US9550741,1 nM to 10 nM
[O-][N+](=O)c1ccc2sc(cc2c1)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1,VDR,active,9.37,Ki,US9550741,1 nM to 10 nM
O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)Nc1cc2ccccc2s1,VDR,active,10,Ki,US9550741,10 nM to 100 nM
Clc1ccc(OC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3nsc4ccccc34)CC2)cc1,VDR,active,11.6,Ki,US9550741,10 nM to 100 nM
CCC(CC)(c1ccc(OCC2CO2)c(C)c1)c1ccc(OCC(=O)C(C)(C)C)c(C)c1,VDR,not active,1000,Ki,10.1016/S1074-5521(99)80072-6,Over 100 nM
Cc1cc(ccc1OCC(=O)C(C)(C)C)C1(CCCCC1)c1ccc(OCC(=O)C(C)(C)C)c(C)c1,VDR,not active,1000,Ki,10.1016/S1074-5521(99)80072-6,Over 100 nM
CC(C)(C)C(=O)COc1ccc(cc1Cl)C(C)(C)c1ccc(OCC(=O)C(C)(C)C)c(Cl)c1,VDR,not active,1000,Ki,10.1016/S1074-5521(99)80072-6,Over 100 nM
Cc1ccc(cc1)-c1csc(=N)n1CC(=O)N1CCN(CC1)c1ccccc1,VDR,not active,1030,Ki,10.1016/j.ejmech.2013.08.021,Over 100 nM
N=c1scc(-c2ccccc2)n1CC(=O)N1CCN(CC1)c1ccccc1,VDR,not active,1600,Ki,10.1016/j.ejmech.2013.08.021,Over 100 nM
CC(=O)N1CCN(CC1)C(=O)Cn1c(csc1=N)-c1ccc(Cl)cc1,VDR,not active,2280,Ki,10.1016/j.ejmech.2013.08.021,Over 100 nM
CC(=O)N1CCN(CC1)C(=O)Cn1c(csc1=N)-c1ccc(C)cc1,VDR,not active,2840,Ki,10.1016/j.ejmech.2013.08.021,Over 100 nM
Clc1ccc(cc1)-c1csc(=N)n1CC(=O)N1CCN(CC1)c1ccccc1,VDR,not active,3070,Ki,10.1016/j.ejmech.2013.08.021,Over 100 nM
CN1CCN(CC1)C(=O)Cn1c(csc1=N)-c1ccc(Cl)cc1,VDR,not active,3660,Ki,10.1016/j.ejmech.2013.08.021,Over 100 nM
Clc1ccc(cc1)-c1csc(=N)n1CC(=O)N1CCOCC1,VDR,not active,4130,Ki,10.1016/j.ejmech.2013.08.021,Over 100 nM
CC(=O)N1CCN(CC1)C(=O)Cn1c(csc1=N)-c1ccccc1,VDR,not active,4660,Ki,10.1016/j.ejmech.2013.08.021,Over 100 nM
Cc1ccc(cc1)-c1csc(=N)n1CC(=O)N1CCOCC1,VDR,not active,13680,Ki,10.1016/j.ejmech.2013.08.021,Over 100 nM
CN1CCN(CC1)C(=O)Cn1c(csc1=N)-c1ccc(C)cc1,VDR,not active,17080,Ki,10.1016/j.ejmech.2013.08.021,Over 100 nM
N=c1scc(-c2ccccc2)n1CC(=O)N1CCOCC1,VDR,not active,24440,Ki,10.1016/j.ejmech.2013.08.021,Over 100 nM
CN1CCN(CC1)C(=O)Cn1c(csc1=N)-c1ccccc1,VDR,not active,28250,Ki,10.1016/j.ejmech.2013.08.021,Over 100 nM
CCC(O)(CC)CC[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,0.029,IC50,10.1021/jm300230a, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@H](CC(C)(C)O)[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,0.12,IC50,10.1021/jm500392t, not Ki or Kd; not used in NCI fingerprint analysis
CCCCCC[C@@H](CCO)[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,0.21,IC50,10.1016/j.bmc.2015.10.026, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@H](CCO)[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,0.26,IC50,10.1021/jm500392t, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@H](CCC(C)(C)O)[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,0.29,IC50,10.1021/jm500392t, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H](CC(O)(CC)CC)[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,0.38,IC50,10.1021/jm300230a, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@@H](CC(O)(CC)CC)[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,0.41,IC50,10.1021/jm300230a, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@H](CCCO)[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,0.89,IC50,10.1021/jm500392t, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCC(=O)C=C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,1.1,IC50,10.1021/acs.jmedchem.8b00774, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@@H](CC[C@]4(C)[C@H]3CC[C@]12C)OS(C)(=O)=O,VDR,active,1.2,IC50,10.1016/j.bmc.2019.07.003, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](CC(O)(CC)CC)[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,1.6,IC50,10.1021/jm500392t, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](CC(C)(C)O)[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,1.6,IC50,10.1021/jm500392t, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@H](CC(O)(CC)CC)[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,1.8,IC50,10.1021/jm500392t, not Ki or Kd; not used in NCI fingerprint analysis
C\C=C\C(=O)CC[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,1.8,IC50,10.1021/acs.jmedchem.8b00774, not Ki or Kd; not used in NCI fingerprint analysis
C\C=C\C#CC(=O)CC[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,1.9,IC50,10.1021/acs.jmedchem.8b00774, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](\C=C\[C@@H](O)C1CC1)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1/C[C@@H](O)C[C@H](O)C1=C,VDR,active,1.9,IC50,PMID:33381963, not Ki or Kd; not used in NCI fingerprint analysis
C\C=C\C=C\C(=O)[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,2.3,IC50,10.1021/acs.jmedchem.8b00774, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](CCC(C)(C)O)[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,2.4,IC50,10.1021/jm500392t, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](CCO)[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,2.9,IC50,10.1021/jm500392t, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](\C=C\C[C@H](O)CC12CC3CC(CC(C3)C1)C2)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,3,IC50,10.1016/j.ejmech.2011.01.047, not Ki or Kd; not used in NCI fingerprint analysis
CCC[C@@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)C[C@H](O)C2=C)OC(=O)C1=C,VDR,active,6,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCC[C@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)C[C@H](O)C2=C)OC(=O)C1=C,VDR,active,6,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCC[C@@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)C[C@H](O)C2=C)OC(=O)C1=C,VDR,active,6,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCC[C@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)C[C@H](O)C2=C)OC(=O)C1=C,VDR,active,6,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](C[C@H]1OC(=O)C(=C)C1(C)C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,6,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](C[C@@H]1CC(=C)C(=O)O1)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,6,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](C[C@H]1OC(=O)C(=C)C11CCCC1)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,6,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](C[C@@H]1OC(=O)C(=C)[C@@H]1C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)[C@H](OCCCO)[C@H](O)C1=C,VDR,active,6.1,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](C[C@H]1OC(=O)C(=C)[C@@H]1C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)[C@H](OCCCO)[C@H](O)C1=C,VDR,active,6.1,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](C[C@@H]1OC(=O)C(=C)[C@H]1C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)[C@H](OCCCO)[C@H](O)C1=C,VDR,active,6.1,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](C[C@H]1OC(=O)C(=C)[C@H]1C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)[C@H](OCCCO)[C@H](O)C1=C,VDR,active,6.1,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](C[C@@H]1OC(=O)C(=C)[C@H]1C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)[C@H](CCCO)[C@H](O)C1=C,VDR,active,6.2,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](C[C@H]1OC(=O)C(=C)[C@H]1C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)[C@H](CCCO)[C@H](O)C1=C,VDR,active,6.2,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](C[C@H]1OC(=O)C(=C)[C@@H]1C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)[C@H](CCCO)[C@H](O)C1=C,VDR,active,6.2,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](C[C@@H]1OC(=O)C(=C)[C@@H]1C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)[C@H](CCCO)[C@H](O)C1=C,VDR,active,6.2,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCC[C@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](C)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,6.3,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCC[C@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](CCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,6.3,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCC[C@@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](C)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,6.3,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCC[C@@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](OCCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,6.3,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCC[C@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](C)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,6.3,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCC[C@@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](OCCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,6.3,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCC[C@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](OCCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,6.3,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCC[C@@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](CCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,6.3,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCC[C@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](OCCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,6.3,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](C[C@H]1CC(=C)C(=O)O1)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,6.3,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCC[C@@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](CCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,6.3,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCC[C@@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](C)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,6.3,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCC[C@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](CCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,6.3,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](C)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,6.7,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](C)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,6.7,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](C)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,6.7,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](C)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,6.7,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](C)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,6.7,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](C)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,6.7,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](C)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,6.7,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](C)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,6.7,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](C[C@@H]1OC(=O)C(=C)[C@H]1C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)[C@H](C)[C@H](O)C1=C,VDR,active,6.8,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](C[C@@H]1OC(=O)C(=C)[C@@H]1C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)[C@H](C)[C@H](O)C1=C,VDR,active,6.8,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H](CCCO)[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,7.2,IC50,10.1021/jm500392t, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](C[C@@H]1OC(=O)C(=C)[C@@H]1C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,7.7,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](C[C@@H]1OC(=O)C(=C)[C@H]1C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,7.7,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](C[C@H]1OC(=O)C(=C)[C@H]1C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)[C@H](C)[C@H](O)C1=C,VDR,active,8.1,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](C[C@H]1OC(=O)C(=C)[C@@H]1C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)[C@H](C)[C@H](O)C1=C,VDR,active,8.1,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)C[C@H](O)C2=C)OC(=O)C1=C,VDR,active,8.2,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)C[C@H](O)C2=C)OC(=O)C1=C,VDR,active,8.2,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)C[C@H](O)C2=C)OC(=O)C1=C,VDR,active,8.2,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)C[C@H](O)C2=C)OC(=O)C1=C,VDR,active,8.2,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](OCCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,8.4,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](CCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,8.4,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](OCCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,8.4,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](CCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,8.4,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](CCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,8.4,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](OCCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,8.4,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](OCCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,8.4,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](CCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,8.4,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)C[C@H](O)C2=C)OC(=O)C1=C,VDR,active,8.6,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)C[C@H](O)C2=C)OC(=O)C1=C,VDR,active,8.6,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)C[C@H](O)C2=C)OC(=O)C1=C,VDR,active,8.6,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC[C@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)C[C@H](O)C2=C)OC(=O)C1=C,VDR,active,8.6,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](CCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,8.8,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](OCCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,8.8,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](OCCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,8.8,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](OCCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,8.8,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](OCCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,8.8,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](CCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,8.8,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](CCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,8.8,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](CCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,8.8,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](C[C@H]1OC(=O)C(=C)[C@H]1C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,9.2,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](OCCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,9.3,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](CCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,9.3,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](OCCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,9.3,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)C[C@H](O)C2=C)OC(=O)C1=C,VDR,active,9.3,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](OCCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,9.3,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](CCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,9.3,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](CCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,9.3,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](OCCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,9.3,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](CCCO)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,9.3,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)C[C@H](O)C2=C)OC(=O)C1=C,VDR,active,9.5,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)C[C@H](O)C2=C)OC(=O)C1=C,VDR,active,10,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)C[C@H](O)C2=C)OC(=O)C1=C,VDR,active,10,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](C)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,11,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](C)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,11,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@H]1[C@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](C)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,11,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](C[C@H]1OC(=O)C(=C)[C@@H]1C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,11,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)C[C@@H]1[C@@H](C[C@@H](C)[C@H]2CC[C@H]3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)[C@H](C)[C@H](O)C2=C)OC(=O)C1=C,VDR,active,11,IC50,10.1021/jm060797q, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCCCNS(=O)(=O)C(F)(F)F)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C[C@H](O)C1,VDR,active,14,IC50,10.1016/j.bmc.2010.03.078, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCCCNS(=O)(=O)c1ccccc1)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C[C@H](O)C1,VDR,active,15,IC50,10.1016/j.bmc.2010.03.078, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@@H](CCC(O)c1ccc(O)cc1)[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,17,IC50,10.1021/acs.jmedchem.7b00819, not Ki or Kd; not used in NCI fingerprint analysis
CCC(O)(CC)CCCO[C@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](C(F)F)C1=C,VDR,active,20,IC50,10.1021/jm0609925, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@@H](CCC(=O)c1ccc(O)cc1)[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,20,IC50,10.1021/acs.jmedchem.7b00819, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@@H](CCC(OC)c1ccc(O)cc1)[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,23,IC50,10.1021/acs.jmedchem.7b00819, not Ki or Kd; not used in NCI fingerprint analysis
CCCCS(=O)(=O)NCCCC[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C[C@H](O)C1,VDR,active,29,IC50,10.1016/j.bmc.2010.03.078, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](C(F)F)C1=C,VDR,active,30,IC50,10.1021/jm0609925, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCCCNC(=O)CS)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C[C@H](O)C1,VDR,active,36,IC50,10.1016/j.bmc.2010.03.078, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCCC(O)c1ccc(O)cc1)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,36,IC50,10.1021/acs.jmedchem.7b00819, not Ki or Kd; not used in NCI fingerprint analysis
C[C@@H](CO[C@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1)C(C)(C)O,VDR,active,38,IC50,10.1016/j.bmcl.2013.08.076, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](COCC#CC(C)(C)C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,47,IC50,10.1021/jm070882d, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](\C=C\C[C@H](O)C12CC3CC(CC(C3)C1)C2)C1CCC2\C(CCCC12C)=C\C=C1C[C@@H](O)C[C@H](O)C1,VDR,active,50,IC50,10.1021/jm050795q, not Ki or Kd; not used in NCI fingerprint analysis
CCC(O)(CC)C(F)(F)CC[C@@H](C)C1=CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](C(F)F)C1=C,VDR,active,50,IC50,10.1021/jm0609925, not Ki or Kd; not used in NCI fingerprint analysis
CCn1cc(cc1C(=O)NCCN1CCN(C)CC1)C(CC)(CC)c1ccc(OCC(C)O)c(C)c1,VDR,active,57,IC50,PMID:33381963, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](COCc1ccccc1)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,63,IC50,10.1021/jm070882d, not Ki or Kd; not used in NCI fingerprint analysis
CCn1cc(cc1C(=O)NC(O)CO)C(CC)(CC)c1ccc(OCC(C)O)c(C)c1,VDR,active,82,IC50,PMID:33381963, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCCC(=O)c1ccc(O)cc1)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,active,84,IC50,10.1021/acs.jmedchem.7b00819, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](COCC(=C)C(C)(C)C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,active,85,IC50,10.1021/jm070882d, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](\C=C(/C)\C=C\C(=O)NO)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1/C[C@@H](O)C[C@@H](O)C1,VDR,active,87,IC50,10.1016/j.bmc.2010.03.078, not Ki or Kd; not used in NCI fingerprint analysis
CCN(CC)CCNC(=O)c1ccc(n1CC)C(CC)(CC)c1ccc(OCSC)c(C)c1,VDR,active,89,IC50,10.1016/j.ejmech.2018.08.085, not Ki or Kd; not used in NCI fingerprint analysis
CCOc1cc(CN2[C@@H](C[C@@H](C)[C@H]3CC[C@H]4\C(CCC[C@]34C)=C\C=C3\C[C@@H](O)C[C@H](O)C3=C)C[C@](C)(O)C2=O)cc(OCC)c1,VDR,active,90,IC50,10.1016/j.bmcl.2008.06.095, not Ki or Kd; not used in NCI fingerprint analysis
CCN(CC)CCCNC(=O)c1ccc(n1CC)C(CC)(CC)c1ccc(OCCC(C)(C)O)c(C)c1,VDR,active,93,IC50,PMID:33381963, not Ki or Kd; not used in NCI fingerprint analysis
COC(CCC[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1)c1ccc(O)cc1,VDR,medium,102,IC50,10.1021/acs.jmedchem.7b00819, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](\C=C(/C)\C=C\C(=O)Nc1ccccc1N)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C[C@H](O)C1,VDR,medium,107,IC50,10.1021/jm1007159, not Ki or Kd; not used in NCI fingerprint analysis
CCN(CC)CCNC(=O)c1cc(cn1CC)C(CC)(CC)c1ccc(OCS(=O)(=O)c2ccccc2)c(C)c1,VDR,medium,125,IC50,10.1016/j.ejmech.2018.08.085, not Ki or Kd; not used in NCI fingerprint analysis
CCCC[C@@H](CCC(O)(c1ccc(O)cc1)c1ccc(O)cc1)[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,medium,130,IC50,10.1021/acs.jmedchem.7b00819, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1onc(c1COc1ccc(-c2nc3ccc(cc3n2CC2CCCCC2)C(O)=O)c(Cl)c1)-c1c(Cl)cccc1Cl,VDR,medium,160,IC50,PMID:32616182, not Ki or Kd; not used in NCI fingerprint analysis
CCCOc1cc(CN2[C@@H](C[C@@H](C)[C@H]3CC[C@H]4\C(CCC[C@]34C)=C\C=C3\C[C@@H](O)C[C@H](O)C3=C)C[C@](C)(O)C2=O)cc(OCCC)c1,VDR,medium,180,IC50,10.1016/j.bmcl.2008.06.095, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCCCC(=O)Nc1ccccc1N)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C[C@H](O)C1,VDR,medium,185,IC50,10.1016/j.bmc.2010.03.078, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](C[C@H]1C[C@](C)(O)C(=O)N1CCc1ccccc1)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,medium,194,IC50,10.1016/j.bmcl.2008.06.095, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCCCCNS(N)(=O)=O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C[C@H](O)C1,VDR,medium,196,IC50,10.1016/j.bmc.2010.03.078, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](COCC(=C)C1(C)CCCCC1)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,medium,198,IC50,10.1021/jm070882d, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCCNS(C)(=O)=O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C[C@H](O)C1,VDR,medium,213,IC50,10.1016/j.bmc.2010.03.078, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCCCC(=O)NO)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C[C@H](O)C1,VDR,medium,248,IC50,10.1016/j.bmc.2010.03.078, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCCCNS(N)(=O)=O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C[C@H](O)C1,VDR,medium,280,IC50,10.1016/j.bmc.2010.03.078, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](COCC(=C)C1=CCCCC1(C)C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,medium,300,IC50,10.1021/jm070882d, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](C[C@H]1CC(=C)C(=O)O1)C1CCC2\C(CCCC12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,medium,300,IC50,10.1021/jm050795q, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(CN2[C@@H](C[C@@H](C)[C@H]3CC[C@H]4\C(CCC[C@]34C)=C\C=C3\C[C@@H](O)C[C@H](O)C3=C)C[C@](C)(O)C2=O)cc(OC)c1,VDR,medium,300,IC50,10.1016/j.bmcl.2008.06.095, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCCCNS(C)(=O)=O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C[C@H](O)C1,VDR,medium,321,IC50,10.1016/j.bmc.2010.03.078, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1onc(c1COc1ccc(cc1)-c1nc2ccc(cc2n1CC1CCCCC1)C(O)=O)-c1c(Cl)cccc1Cl,VDR,medium,346,IC50,PMID:32616182, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](C[C@H]1C[C@](C)(O)C(=O)N1CCCCc1ccccc1)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,medium,390,IC50,10.1016/j.bmcl.2008.06.095, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCCC(O)(c1ccc(O)cc1)c1ccc(O)cc1)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C(=C)[C@H](O)C1,VDR,medium,520,IC50,10.1021/acs.jmedchem.7b00819, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](CCCC(=O)Nc1ccccc1N)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1C[C@@H](O)C[C@H](O)C1,VDR,medium,524,IC50,10.1016/j.bmc.2010.03.078, not Ki or Kd; not used in NCI fingerprint analysis
CCCCOc1cc(CN2[C@@H](C[C@@H](C)[C@H]3CC[C@H]4\C(CCC[C@]34C)=C\C=C3\C[C@@H](O)C[C@H](O)C3=C)C[C@](C)(O)C2=O)cc(OCCCC)c1,VDR,medium,540,IC50,10.1016/j.bmcl.2008.06.095, not Ki or Kd; not used in NCI fingerprint analysis
COc1ccc(CN2[C@@H](C[C@@H](C)[C@H]3CCC4\C(CCC[C@]34C)=C\C=C3\C[C@@H](O)C[C@H](O)C3=C)C[C@](C)(O)C2=O)cc1,VDR,medium,660,IC50,10.1021/jm050738x, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](C[C@H]1C[C@](C)(O)C(=O)N1Cc1ccccc1)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,medium,700,IC50,10.1016/j.bmcl.2008.06.095, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(CCCN2[C@@H](C[C@@H](C)[C@H]3CC[C@H]4\C(CCC[C@]34C)=C\C=C3\C[C@@H](O)C[C@H](O)C3=C)C[C@](C)(O)C2=O)cc(OC)c1,VDR,medium,780,IC50,10.1016/j.bmcl.2008.06.095, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1onc(c1COc1ccc(-c2nc3ccc(cc3n2CC2CCCCC2)C(O)=O)c(F)c1)-c1c(Cl)cccc1Cl,VDR,medium,840,IC50,PMID:32616182, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(CCN2[C@@H](C[C@@H](C)[C@H]3CC[C@H]4\C(CCC[C@]34C)=C\C=C3\C[C@@H](O)C[C@H](O)C3=C)C[C@](C)(O)C2=O)cc(OC)c1,VDR,medium,860,IC50,10.1016/j.bmcl.2008.06.095, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1onc(c1COc1ccc(cc1)-c1nc2ccc(cc2n1CC(C)(C)C)C(O)=O)-c1c(Cl)cccc1Cl,VDR,medium,861,IC50,PMID:32616182, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1onc(c1COc1ccc(cc1)-c1nc2ccc(cc2n1C1CCCCCC1)C(O)=O)-c1c(Cl)cccc1Cl,VDR,medium,921,IC50,PMID:32616182, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1onc(c1COc1ccc(cc1)-c1nc2ccc(cc2n1C1CCCC1)C(O)=O)-c1c(Cl)cccc1Cl,VDR,medium,929,IC50,PMID:32616182, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)N1[C@@H](C[C@@H](C)[C@H]2CCC3\C(CCC[C@]23C)=C\C=C2\C[C@@H](O)C[C@H](O)C2=C)C[C@](C)(O)C1=O,VDR,not active,1000,IC50,10.1021/jm050738x, not Ki or Kd; not used in NCI fingerprint analysis
CCC(CC)n1c(nc2ccc(cc12)C(O)=O)-c1ccc(OCc2c(onc2-c2c(Cl)cccc2Cl)C(C)C)cc1Cl,VDR,not active,1013,IC50,PMID:32616182, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1onc(c1COc1ccc(cc1)-c1nc2ccc(cc2n1C1CCC1)C(O)=O)-c1c(Cl)cccc1Cl,VDR,not active,1104,IC50,PMID:32616182, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1onc(c1COc1ccc(cc1)-c1nc2ccc(cc2n1Cc1ccc(F)cc1)C(O)=O)-c1c(Cl)cccc1Cl,VDR,not active,1142,IC50,PMID:32616182, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)Cn1c(nc2ccc(cc12)C(O)=O)-c1ccc(OCc2c(onc2-c2c(Cl)cccc2Cl)C(C)C)cc1,VDR,not active,1183,IC50,PMID:32616182, not Ki or Kd; not used in NCI fingerprint analysis
CCCn1c(nc2ccc(cc12)C(O)=O)-c1ccc(OCc2c(onc2-c2c(Cl)cccc2Cl)C(C)C)cc1,VDR,not active,1401,IC50,PMID:32616182, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1onc(c1COc1ccc(cc1)-c1nc2ccc(cc2n1C1CCCCC1)C(O)=O)-c1c(Cl)cccc1Cl,VDR,not active,1449,IC50,PMID:32616182, not Ki or Kd; not used in NCI fingerprint analysis
Nc1nc2ccc(cc2s1)S(=O)(=O)N1CCCCC1,VDR,not active,2000,IC50,10.1021/jm300460c, not Ki or Kd; not used in NCI fingerprint analysis
C[C@H](C[C@H]1C[C@](C)(O)C(=O)N1CCCc1ccccc1)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C,VDR,not active,2200,IC50,10.1016/j.bmcl.2008.06.095, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1onc(c1COc1ccc(cc1)-c1nc2ccc(cc2n1-c1ccc(F)cc1)C(O)=O)-c1c(Cl)cccc1Cl,VDR,not active,2414,IC50,PMID:32616182, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1onc(c1COc1ccc(cc1Cl)-c1nc2ccc(cc2n1C)C(O)=O)-c1c(Cl)cccc1Cl,VDR,not active,2454,IC50,PMID:32616182, not Ki or Kd; not used in NCI fingerprint analysis
CC(C)c1onc(c1COc1ccc(cc1)-c1nc2ccc(cc2n1CC1CC1)C(O)=O)-c1c(Cl)cccc1Cl,VDR,not active,2653,IC50,PMID:32616182, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(CN2[C@H](C[C@@H](C)[C@H]3CC[C@H]4\C(CCC[C@]34C)=C\C=C3\C[C@@H](O)C[C@H](O)C3=C)C[C@](C)(O)C2=O)cc(OC)c1,VDR,not active,3000,IC50,10.1016/j.bmcl.2008.06.095, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(CN2[C@H](C[C@@H](C)[C@H]3CC[C@H]4\C(CCC[C@]34C)=C\C=C3\C[C@@H](O)C[C@H](O)C3=C)C[C@@](C)(O)C2=O)cc(OC)c1,VDR,not active,3000,IC50,10.1016/j.bmcl.2008.06.095, not Ki or Kd; not used in NCI fingerprint analysis
COc1cc(CN2[C@@H](C[C@@H](C)[C@H]3CC[C@H]4\C(CCC[C@]34C)=C\C=C3\C[C@@H](O)C[C@H](O)C3=C)C[C@@](C)(O)C2=O)cc(OC)c1,VDR,not active,3000,IC50,10.1016/j.bmcl.2008.06.095, not Ki or Kd; not used in NCI fingerprint analysis