Table 4S. Detailed clinical information for the 133 AML PB samples from TCGA database bcr-patient-barcode birth_days_to gender race history_other_malignancy history_hematologic_disorder history_neoadjuvant_treatment history_neoadjuvant_hydroxyurea_tx hydroxyurea_tx_days total_dose history_exposure_leukemogenic_agents history_chemical_exposure_other vital_status last_contact_days_to death_days_to cells_used_for_analysis_source initial_pathologic_dx_year age_at_diagnosis percent_blasts_peripheral_blood fab_category cyto_and_immuno_test_performed percent_cellularity wbc_24hr_of_banking hemoglobin_24hr_of_banking platelet_count_preresection blast_count promyelocytes_count myelocytes_24hr_of_banking metamyelocytes_24hr_of_banking bands_24hr_of_banking segs_24hr_of_banking basophils_count basophils_count lymphocytes_count monocytes_count prolymphocytes_24hr_of_banking promonocytes_24hr_of_banking abnormal_lymphocyte_percent cytogenetics_testing_performed metaphases_count cyto_risk_group cytogenetic_abnormality_type cyto_abnormality_type_other fish_performed_indicator fish_abnormality_detected test_performed_indicator fish_performed_outcome molecular_abnormality_detected molecular_abnormality_results informed_consent_verified initial_pathologic_dx_days_to tissue_source_site TCGA-AB-2803 -22584 FEMALE WHITE No NO No NO 0 0 No Exposure [Not Available] Dead [Not Available] 792 Bone marrow aspirate 2001 61 44 M3 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Negative|CD10 Not Tested|CD14 Negative|CD15 Negative|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Negative|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Negative|Other CD Not Tested 90 1 10 90 0 0 0 0 0 9 0 0 91 0 0 0 0 YES 25 Favorable Normal t(15;17) YES YES PML-RAR 95 YES PML-RAR Positive|FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2806 -16892 MALE WHITE No NO Yes YES 3 4000 None [Not Available] Dead [Not Available] 945 Bone marrow aspirate 2002 46 90 M1 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Positive|CD19 Positive|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Positive|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Not Tested [Not Available] 29 9 90 81 13 0 0 0 0 0 0 6 0 0 0 0 YES 20 Favorable t(8;21) [Not Available] NO [Not Available] [Not Available] [Not Available] [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2808 -8521 MALE WHITE No NO No NO 0 0 No Exposure [Not Available] Alive 2861 [Not Applicable] Bone marrow aspirate 2002 23 59 M2 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Positive|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Positive|CD56 Positive|CD117 Positive|HLA-DR Positive|Other CD Not Tested 70 32 7 38 0 0 0 0 21 7 2 0 15 9 0 0 0 YES 17 Intermediate/Normal Normal [Not Available] YES NO [Not Available] [Not Available] [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2810 -27971 FEMALE BLACK OR AFRICAN AMERICAN No NO No NO 0 0 None [Not Available] Dead [Not Available] 31 Bone marrow aspirate 2002 76 48 M2 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Not Tested|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Not Tested 95 62 10 32 88 0 3 1 1 1 0 0 4 2 0 0 0 NO [Not Available] [Not Available] [Not Available] No NO [Not Available] [Not Available] [Not Available] [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Positive|IDH1 R172 Negative|Activating RAS Negative|NPMc Positive YES 0 AB TCGA-AB-2813 -28581 MALE WHITE No NO No NO [Not Available] [Not Available] [Not Available] [Not Available] Dead [Not Available] 31 Bone marrow aspirate 2005 78 40 M4 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Positive|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Positive|CD117 Positive|HLA-DR Not Tested|Other CD Not Tested 80 10 10 98 6 3 4 3 7 13 0 0 23 25 0 14 0 YES 20 Poor Complex - >= 3 distinct abnormalities|del(5q) / 5q- 21 YES YES BCR-ABL 23 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2814 -14427 FEMALE WHITE No NO No NO 0 0 None [Not Available] Dead [Not Available] 792 Bone marrow aspirate 2003 39 75 M0 Undifferentiated MPX Negative|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Positive|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Not Tested 10 2 10 215 4 0 0 0 3 8 0 0 60 9 0 0 16 YES 20 Intermediate/Normal del(5q) / 5q- [Not Available] YES NO PML-RAR 3 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2815 -17988 MALE WHITE No NO Yes YES 3 5000 None [Not Available] Dead [Not Available] 822 Bone marrow aspirate 2004 49 81 M4 MPX Positive|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Positive|Other CD Negative 95 57 8 14 48 0 0 0 0 2 1 0 11 26 0 0 11 YES 20 Favorable inv(16) [Not Available] YES YES BCR-ABL|PML-RAR|CBF-Beta 4|1|59 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2816 -20939 FEMALE WHITE No NO Yes YES 3 11000 None [Not Available] Dead [Not Available] 245 Bone marrow aspirate 2003 57 90 M4 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Positive|CD10 Not Tested|CD14 Positive|CD15 Not Tested|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Negative|CD45 Positive|CD56 Negative|CD117 Positive|HLA-DR Positive|Other CD Positive 80 88 10 56 84 0 0 0 0 0 0 0 3 3 0 0 10 YES 20 Intermediate/Normal Normal [Not Available] NO [Not Available] [Not Available] [Not Available] [Not Available] FLT3 Mutation Positive|IDH1 R132 Positive|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Positive|NPMc Positive YES 0 AB TCGA-AB-2817 -23376 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] 273 Bone marrow aspirate 2005 64 57 M2 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Negative|CD14 Negative|CD15 Not Tested|CD19 Positive|CD20 Negative|CD23 Not Tested|CD25 Not Tested|CD33 Not Tested|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Negative 90 77 13 19 70 3 0 6 7 3 1 0 8 2 0 0 0 YES 20 Poor Normal|del(7q) / 7q- t(9;22) YES YES BCR-ABL 97 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2819 -19054 FEMALE WHITE Yes NO No NO [Not Available] [Not Available] None [Not Available] Alive 2496 [Not Applicable] Bone marrow aspirate 2003 52 67 M2 MPX Positive|NSE Negative|TDT Negative|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Negative|CD14 Not Tested|CD15 Not Tested|CD19 Positive|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Negative|CD34 Positive|CD45 Positive|CD56 Positive|CD117 Positive|HLA-DR Positive|Other CD Negative 60 4 9 22 18 0 0 1 6 22 0 0 45 8 0 0 0 YES 20 Favorable Normal|t(8;21) [Not Available] NO [Not Available] [Not Available] [Not Available] [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2820 -27971 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] 0 Bone marrow aspirate 2003 76 74 M0 Undifferentiated MPX Negative|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Negative|CD20 Not Tested|CD23 Negative|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Not Tested 90 15 9 85 82 0 0 0 0 0 0 0 18 1 0 0 0 YES 17 Poor Complex - >= 3 distinct abnormalities|+8 [Not Available] NO [Not Available] [Not Available] [Not Available] [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2821 -23527 MALE WHITE No NO No NO [Not Available] [Not Available] [Not Available] [Not Available] Dead [Not Available] 822 Bone marrow aspirate 2005 64 61 M1 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Not Tested|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Not Tested 20 1 8 42 5 0 0 0 0 13 0 0 74 6 0 0 2 YES 20 Poor Normal|+8 [Not Available] YES YES 8 57 [Not Available] FLT3 Mutation Negative|IDH1 R132 Positive|IDH1 R140 Negative|IDH1 R172 Positive|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2822 -24017 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] 973 Bone marrow aspirate 2003 65 99 M0 Undifferentiated MPX Negative|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Negative|CD34 Positive|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Not Tested|Other CD Not Tested 50 3 9 16 34 0 0 0 0 1 0 0 45 4 0 0 16 YES 20 Poor 8 [Not Available] NO [Not Available] [Not Available] [Not Available] NO BCR-ABL Negative|FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2823 -22522 FEMALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] 0 Bone marrow aspirate 2006 61 73 M3 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Not Tested|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Not Tested 80 86 12 22 68 22 0 0 2 5 0 0 3 0 0 0 0 YES 20 Favorable t(15;17) and variants [Not Available] YES YES PML-RAR 99 [Not Available] FLT3 Mutation Positive|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2824 -16437 MALE WHITE No NO No NO [Not Available] [Not Available] [Not Available] [Not Available] Dead [Not Available] 30 Bone marrow aspirate 2004 45 74 M5 MPX Negative|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Not Tested|CD45 Positive|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Not Tested 90 9 8 50 5 0 1 0 0 37 0 1 33 23 0 0 0 YES [Not Available] Intermediate/Normal Normal [Not Available] NO [Not Available] [Not Available] [Not Available] [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Positive YES 0 AB TCGA-AB-2828 -20393 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 2284 [Not Applicable] Bone marrow aspirate 2003 55 35 M4 MPX Positive|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Not Tested 95 22 8 65 67 0 1 1 1 12 0 0 14 0 0 0 4 YES 20 Favorable [Not Available] [Not Available] YES YES CBF-Beta 97 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2832 -21915 FEMALE WHITE No NO No NO [Not Available] [Not Available] [Not Available] [Not Available] Dead [Not Available] 365 Bone marrow aspirate 2005 60 95 M5 MPX Negative|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Negative|CD34 Not Tested|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Not Tested 100 12 11 57 0 0 0 0 0 1 0 0 23 76 0 0 0 YES 30 Intermediate/Normal Normal [Not Available] YES YES PML-RAR|MLL 2|13 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2833 -28308 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] 456 Bone marrow aspirate 2002 77 80 M4 MPX Not Tested|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Positive|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Not Tested 70 40 10 29 2 0 0 0 0 7 0 0 20 40 0 0 0 YES 20 Intermediate/Normal Normal [Not Available] YES NO [Not Available] [Not Available] [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2834 -12266 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] 245 Bone marrow aspirate 2004 33 71 M4 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Not Tested|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Positive|Other CD Positive 90 26 10 111 14 5 1 0 5 25 3 0 10 37 0 0 0 YES 20 Intermediate/Normal [Not Available] [Not Available] YES YES BCR-ABL|MLL|AML1-ETO|TEL-AML 1 6|91|1|0 [Not Available] FLT3 Mutation Positive|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2835 -17624 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 1673 [Not Applicable] Bone marrow aspirate 2005 48 83 M5 MPX Negative|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Not Tested|CD45 Not Tested|CD56 Not Tested|CD 117 Not Tested|HLA-DR Not Tested|Other CD Positive 90 116 9 50 3 1 0 0 1 4 0 0 6 45 0 0 40 YES 20 Intermediate/Normal Normal [Not Available] NO [Not Available] [Not Available] [Not Available] [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Positive YES 0 AB TCGA-AB-2837 -24381 FEMALE WHITE No NO Yes YES 3 3000 [Not Available] [Not Available] Dead [Not Available] 0 Bone marrow aspirate 2002 66 90 M5 MPX Negative|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Positive|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Not Tested|CD45 Not Tested|CD56 Not Tested|CD 117 Not Tested|HLA-DR Not Tested|Other CD Positive 90 112 10 34 7 6 3 4 6 20 1 1 0 0 0 0 30 YES 20 Intermediate/Normal Normal [Not Available] NO [Not Available] [Not Available] [Not Available] [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Positive YES 0 AB TCGA-AB-2838 -24503 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] 365 Bone marrow aspirate 2002 67 50 M2 MPX Not Tested|NSE Not Tested|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Positive|Other CD Not Tested 60 2 9 28 17 1 0 1 1 3 0 0 53 10 0 3 8 YES 20 Poor Complex - >= 3 distinct abnormalities|del(5q) / 5q-|del(7q) / 7q-|+8 21 NO [Not Available] [Not Available] [Not Available] [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2840 -27243 MALE WHITE No YES Yes YES 3 5000 None [Not Available] Dead [Not Available] 28 Bone marrow aspirate 2003 74 51 M3 MPX Positive|NSE Negative|TDT Not Tested|CD3 Negative|CD5 Negative|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Positive|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Negative|CD45 Positive|CD56 Negative|CD117 Positive|HLA-DR Negative|Other CD Not Tested 95 32 9 42 0 71 0 1 1 0 0 0 27 0 0 0 0 YES 20 Favorable t(15;17) and variants [Not Available] YES NO BCR-ABL 0 NO BCR-ABL Negative|[Not Evaluated]|FLT3 Mutation Positive|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2841 -18809 FEMALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] 1401 Bone marrow aspirate 2004 51 93 M3 MPX Positive|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Negative|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Negative|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Negative|Other CD Negative 95 4 8 58 40 14 4 0 0 7 1 1 27 6 0 0 8 YES 20 Favorable t(15;17) and variants No YES YES PML-RAR 96 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2842 -23741 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] 0 Bone marrow aspirate 2004 65 95 M4 MPX Positive|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Negative|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Positive|Other CD Positive 70 2 12 27 0 0 0 0 0 35 2 0 57 6 0 0 0 YES 20 Intermediate/Normal [Not Available] [Not Available] NO [Not Available] [Not Available] [Not Available] [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2843 -28275 MALE WHITE No NO No NO [Not Available] [Not Available] [Not Available] [Not Available] Dead [Not Available] 215 Bone marrow aspirate 2004 77 75 M6 MPX Not Tested|NSE Not Tested|TDT Negative|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Positive|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Not Tested 95 3 9 86 8 0 0 0 1 9 0 6 62 9 1 0 4 YES 32 Intermediate/Normal [Not Available] [Not Available] YES YES MLL 7.5 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2844 -23254 MALE WHITE No NO No NO [Not Available] [Not Available] [Not Available] [Not Available] Dead [Not Available] 122 Bone marrow aspirate 2005 63 80 M2 MPX Positive|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Not Tested 75 17 12 23 71 0 0 0 0 9 0 0 20 0 0 0 0 YES 20 Intermediate/Normal [Not Available] [Not Available] YES YES PML-RAR|MLL|CBF-Beta|AML1-ETO|TEL-AML 1 2|87|1|1|2 [Not Available] FLT3 Mutation Positive|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2846 -20910 FEMALE WHITE No [Not Available] No NO [Not Available] [Not Available] [Not Available] [Not Available] Dead [Not Available] 1402 Bone marrow aspirate 2005 57 61 M4 MPX Positive|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Not Tested|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Not Tested 100 14 9 76 17 0 0 0 0 6 3 0 18 51 0 0 4 YES 20 Favorable inv(16) [Not Available] YES YES CBF-Beta 90 [Not Available] FLT3 Mutation Positive|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2847 -19481 MALE WHITE Yes NO No NO 0 0 Benzene [Not Available] Dead [Not Available] 608 Bone marrow aspirate 2004 53 72 M1 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Positive|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Not Tested 30 3 9 108 41 0 0 0 0 2 1 0 43 13 0 0 0 YES 20 Intermediate/Normal Normal|del(7q) / 7q- [Not Available] YES YES CBF-Beta|-7 or del(7q) 0|63 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2848 -22980 MALE WHITE No NO Yes YES 2 4000 [Not Available] [Not Available] Dead [Not Available] 455 Bone marrow aspirate 2005 62 65 M4 MPX Positive|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Not Tested|CD34 Not Tested|CD45 Not Tested|CD56 Not Tested|CD 117 Not Tested|HLA-DR Not Tested|Other CD Not Tested 80 119 11 52 65 5 2 0 4 5 0 0 10 0 0 0 2 YES 20 Intermediate/Normal Normal No YES NO PML-RAR|CBF-Beta|AML1-ETO|TEL-AML 1 2|2|0|2 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Positive YES 0 AB TCGA-AB-2849 -14520 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 2220 [Not Applicable] Bone marrow aspirate 2004 39 83 M0 Undifferentiated MPX Not Tested|NSE Negative|TDT Positive|CD3 Not Tested|CD5 Not Tested|CD7 Positive|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Not Tested|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Not Tested 90 5 10 175 53 1 3 1 4 16 0 0 17 1 0 0 4 YES 20 Intermediate/Normal [Not Available] [Not Available] YES YES BCR-ABL|PML-RAR|MLL|Other 0|100|0|100 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2854 -18809 FEMALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] 366 Bone marrow aspirate 2003 51 73 M4 MPX Not Tested|NSE Not Tested|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Not Tested|CD34 Positive|CD45 Positive|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Positive 40 3 11 143 2 0 0 0 2 6 3 0 42 45 0 0 0 YES 20 Intermediate/Normal [Not Available] [Not Available] NO [Not Available] [Not Available] [Not Available] [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2855 -6636 MALE WHITE No NO No NO [Not Available] [Not Available] [Not Available] [Not Available] Dead [Not Available] 212 Bone marrow aspirate 2004 18 86 M1 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Positive|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Not Tested 90 35 9 30 90 0 0 0 0 1 0 0 5 4 0 0 0 YES 20 Poor Complex - >= 3 distinct abnormalities [Not Available] YES YES TEL-AML 1|Other 0|99 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2857 -19905 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] 306 Bone marrow aspirate 2005 54 30 M6 MPX Not Tested|NSE Not Tested|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Positive|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Not Tested 100 2 9 9 0 0 0 1 21 14 1 3 55 1 0 0 4 YES 23 Poor Complex - >= 3 distinct abnormalities|del(5q) / 5q-|del(7q) / 7q- [Not Available] YES YES -5 or del(5q)|Other 56|85 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2858 -27547 FEMALE WHITE No NO No NO [Not Available] [Not Available] [Not Available] [Not Available] Dead [Not Available] 577 Bone marrow aspirate 2004 75 48 M2 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Positive|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Not Tested 35 8 9 21 54 0 0 0 0 20 0 0 22 0 0 0 4 YES 20 Favorable t(8;21) [Not Available] YES YES AML1-ETO 89 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2860 -22035 FEMALE WHITE No NO No NO [Not Available] [Not Available] [Not Available] [Not Available] Dead [Not Available] 427 Bone marrow aspirate 2003 60 58 M7 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Negative|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Positive|CD56 Positive|CD117 Positive|HLA-DR Positive|Other CD Positive 70 1 9 59 0 0 0 0 0 18 2 0 64 2 0 0 14 YES 20 Poor Complex - >= 3 distinct abnormalities|del(5q) / 5q-|del(7q) / 7q- t(4;11) NO [Not Available] [Not Available] [Not Available] [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2861 -27940 MALE WHITE No NO No NO [Not Available] [Not Available] [Not Available] [Not Available] Dead [Not Available] 0 Bone marrow aspirate 2005 76 78 M5 MPX Negative|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Positive|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Negative|CD45 Not Tested|CD56 Positive|CD 117 Not Tested|HLA-DR Positive|Other CD Positive 90 4 10 79 0 3 1 4 22 19 2 0 36 10 0 0 2 YES 20 Poor Normal|+8 [Not Available] YES YES PML-RAR|CBF-Beta 2|1 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Positive YES 0 AB TCGA-AB-2862 -12266 FEMALE BLACK OR AFRICAN AMERICAN No NO No NO [Not Available] [Not Available] [Not Available] [Not Available] Alive 1430 [Not Applicable] Bone marrow aspirate 2005 33 100 M3 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Not Tested|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Not Tested 100 1 9 38 0 0 0 0 0 10 0 0 88 0 0 0 2 YES 20 Intermediate/Normal Normal [Not Available] YES YES PML-RAR 93 [Not Available] FLT3 Mutation Positive|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2863 -23132 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] 31 Bone marrow aspirate 2003 63 81 M1 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Negative|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Negative|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Negative 95 46 8 11 97 0 0 0 0 1 0 0 2 0 0 0 0 YES 20 Poor 8 [Not Available] YES NO BCR-ABL|PML-RAR 0|0 NO BCR-ABL Negative|FLT3 Mutation Negative|IDH1 R132 Positive|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2865 -27486 MALE WHITE No NO No NO [Not Available] [Not Available] [Not Available] [Not Available] Dead [Not Available] 61 Bone marrow aspirate 2005 75 40 M1 MPX Negative|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Negative|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD 117 Not Tested|HLA-DR Not Tested|Other CD Not Tested 90 6 9 22 48 0 0 0 4 20 0 0 23 4 0 0 1 YES 19 Intermediate/Normal [Not Available] 21 YES YES PML-RAR|CBF-Beta|Other 2|1|94 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2868 -28216 MALE WHITE No NO No NO [Not Available] [Not Available] [Not Available] [Not Available] Dead [Not Available] 151 Bone marrow aspirate 2002 77 47 M7 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Positive|CD56 Positive|CD117 Positive|HLA-DR Positive|Other CD Positive 80 2 10 70 0 0 0 0 0 11 0 0 87 2 0 0 0 YES 20 Favorable Complex - >= 3 distinct abnormalities|del(5q) / 5q-|+8 21 NO [Not Available] [Not Available] [Not Available] [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2869 -23679 FEMALE BLACK OR AFRICAN AMERICAN No NO No NO 0 0 None [Not Available] Alive 243 [Not Applicable] Bone marrow aspirate 2009 64 80 M2 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Negative|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Positive|Other CD Negative 95 3 10 41 46 0 0 0 0 2 0 1 49 2 0 0 0 YES 20 Intermediate/Normal Normal [Not Available] YES NO PML-RAR|MLL|CBF-Beta|AML1-ETO|+8|-7 or del(7q)|-5 or del(5q)|del (20q) 0|0|0|0|0|0|0|0 YES PML-RAR Positive|IDH1 R132 Negative|[Not Evaluated]|[Not Evaluated]|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2870 -27787 MALE WHITE No NO Yes YES 3 6000 None [Not Available] Dead [Not Available] 153 Bone marrow aspirate 2007 76 73 M1 MPX Positive|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Not Tested 90 34 8 21 55 0 0 0 0 5 0 0 16 21 0 3 0 YES 20 Favorable Normal|inv(16) [Not Available] YES YES BCR-ABL|PML-RAR|MLL|CBF-Beta|AML1-ETO|+8|-7 or del(7q) 0|0|0|66|0|0|0 NO FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2871 -18689 MALE BLACK OR AFRICAN AMERICAN No [Not Available] No NO 0 0 None [Not Available] Alive 153 [Not Applicable] Bone marrow aspirate 2009 51 62 M1 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Not Tested 45 2 10 25 10 0 0 0 0 10 0 0 71 0 4 0 5 YES 20 Intermediate/Normal Normal [Not Available] NO [Not Available] [Not Available] [Not Available] NO FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2872 -15461 MALE BLACK OR AFRICAN AMERICAN No NO No NO [Not Available] [Not Available] None [Not Available] Alive 638 [Not Applicable] Bone marrow aspirate 2008 42 88 M3 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Negative|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Negative|Other CD Positive 90 2 9 35 2 5 0 0 2 6 0 0 79 4 0 0 2 YES 20 Favorable Complex - >= 3 distinct abnormalities|t(15;17) and variants [Not Available] YES YES PML-RAR 98 YES PML-RAR Positive|FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2873 -18689 FEMALE WHITE No NO Yes YES 3 12000 None [Not Available] Alive 273 [Not Applicable] Bone marrow aspirate 2009 51 57 M5 MPX Negative|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Positive|CD117 Positive|HLA-DR Positive|Other CD Negative 90 15 11 14 0 0 0 0 0 20 0 0 21 59 0 0 0 YES 20 Intermediate/Normal Normal [Not Available] YES NO BCR-ABL|PML-RAR|MLL|CBF-Beta|AML1-ETO|+8|-7 or del(7q)|-5 or del(5q) 0|0|0|0|0|0|0|0 YES FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2874 -21764 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 396 [Not Applicable] Bone marrow aspirate 2009 59 70 M2 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Negative|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Positive|Other CD Not Tested 80 12 11 20 48 0 0 0 2 16 0 1 14 19 0 0 0 YES 20 Poor del(7q) / 7q- [Not Available] YES YES PML-RAR|MLL|CBF-Beta|AML1-ETO|+8|-7 or del(7q)|-5 or del(5q) 0|0|0|0|0|99|0 NO FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Positive|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2875 -16010 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 212 [Not Applicable] Bone marrow aspirate 2009 43 40 M2 MPX Not Tested|NSE Not Tested|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Not Tested|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Not Tested 45 4 11 67 39 0 4 0 3 21 0 0 29 4 0 0 0 YES 20 Favorable t(8;21) [Not Available] YES YES PML-RAR|MLL|CBF-Beta|AML1-ETO|+8|-7 or del(7q)|-5 or del(5q) 0|0|0|89|0|0|0 YES FLT3 Mutation Positive|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2876 -16648 FEMALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 1219 [Not Applicable] Bone marrow aspirate 2006 45 56 M2 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Not Tested 90 29 8 116 37 0 1 1 5 36 4 1 13 2 0 0 0 YES 20 Intermediate/Normal Normal [Not Available] YES NO BCR-ABL|PML-RAR|MLL 0|0|0 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2877 -21946 FEMALE WHITE Yes NO No NO [Not Available] [Not Available] None [Not Available] Alive 638 [Not Applicable] Bone marrow aspirate 2008 60 86 M1 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Negative|CD45 Not Tested|CD56 Positive|CD117 Positive|HLA-DR Negative|Other CD Not Tested 90 12 9 45 43 0 1 0 3 4 3 0 45 0 0 0 1 YES 20 Intermediate/Normal [Not Available] [Not Available] YES NO BCR-ABL|PML-RAR|MLL|Other 1|1|0|0 [Not Available] FLT3 Mutation Positive|IDH1 R132 Negative|IDH1 R140 Positive|IDH1 R172 Negative|Activating RAS Negative|NPMc Positive YES 0 AB TCGA-AB-2878 -17501 FEMALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] 365 Bone marrow aspirate 2006 47 37 M2 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Not Tested 70 12 9 57 0 0 0 0 0 70 5 6 10 9 0 0 0 YES 20 Poor Complex - >= 3 distinct abnormalities|del(5q) / 5q-|del(7q) / 7q- [Not Available] YES YES BCR-ABL|+8 3|93 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2879 -25141 FEMALE WHITE No NO Yes YES 2 2000 None [Not Available] Alive 245 [Not Applicable] Bone marrow aspirate 2009 68 90 M1 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Negative|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Negative|CD45 Positive|CD56 Negative|CD117 Positive|HLA-DR Negative|Other CD Negative 70 60 9 8 91 1 1 0 1 2 0 0 3 1 0 0 0 YES 20 Intermediate/Normal Normal [Not Available] YES NO PML-RAR|CBF-Beta|AML1-ETO|TEL-AML 1|+8|-7 or del(7q)|-5 or del(5q) 0|0|1|0|0|0|0 YES PML-RAR Negative|FLT3 Mutation Positive|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Positive YES 0 AB TCGA-AB-2880 -8827 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Dead 424 [Not Available] Bone marrow aspirate 2009 24 77 M1 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Negative|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Negative 90 224 6 34 76 1 0 0 1 1 0 0 5 4 0 12 0 YES 20 Intermediate/Normal Normal [Not Available] YES NO BCR-ABL|PML-RAR|MLL|CBF-Beta|AML1-ETO|+8|-7 or del(7q)|-5 or del(5q) 0|0|0|0|0|0|0|0 YES FLT3 Mutation Positive|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2881 -17808 FEMALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 393 [Not Applicable] Bone marrow aspirate 2009 48 75 M1 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Negative|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Negative|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Negative 90 33 10 32 41 0 1 0 2 2 0 0 26 17 0 10 2 YES 20 Favorable Normal|inv(16) [Not Available] YES YES PML-RAR|MLL|CBF-Beta|AML1-ETO|+8|-7 or del(7q)|-5 or del(5q) 0|0|89|0|0|0|0 NO FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2882 -26844 FEMALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] 365 Bone marrow aspirate 2006 73 37 M2 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Not Tested|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Not Tested 80 2 10 60 16 0 0 0 0 20 0 0 54 8 0 0 2 YES 20 Poor Normal|del(7q) / 7q- [Not Available] NO [Not Available] [Not Available] [Not Available] [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2883 -22067 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 730 [Not Applicable] Bone marrow aspirate 2008 60 94 M5 MPX Not Tested|NSE Not Tested|TDT Not Tested|CD3 Not Tested|CD5 Negative|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Not Tested|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Positive|Other CD Negative 90 7 9 93 30 0 1 0 0 5 0 0 49 12 0 2 0 YES 20 Poor Normal|Complex - >= 3 distinct abnormalities|+8 21 YES YES MLL 82 NO BCR-ABL Negative|FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2884 -16285 FEMALE WHITE No NO Yes YES 3 10000 None [Not Available] Dead [Not Available] 731 Bone marrow aspirate 2008 44 86 M1 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Not Tested|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Not Tested 85 14 9 145 17 0 1 0 0 10 0 0 27 38 0 5 2 YES 20 Intermediate/Normal Normal [Not Available] YES NO PML-RAR|CBF-Beta|AML1-ETO 0|0|0 NO FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Positive YES 0 AB TCGA-AB-2885 -26176 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] 214 Bone marrow aspirate 2009 71 97 M0 Undifferentiated MPX Negative|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Negative|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Positive|Other CD Negative 50 5 8 48 54 0 0 0 0 4 1 0 33 0 0 0 8 YES 20 Poor Complex - >= 3 distinct abnormalities|del(5q) / 5q-|del(7q) / 7q- [Not Available] YES YES -7 or del(7q)|-5 or del(5q)|del (20q) 90|95|94 NO FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2886 -9497 MALE WHITE No NO Yes YES 3 4000 None [Not Available] Alive 181 [Not Applicable] Bone marrow aspirate 2009 26 72 M2 MPX Positive|NSE Negative|TDT Positive|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Positive|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Not Tested|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Not Tested 90 11 9 33 50 0 1 0 1 19 0 0 27 2 0 0 0 YES 20 Favorable t(8;21) Yes YES YES PML-RAR|MLL|CBF-Beta|AML1-ETO|+8|-7 or del(7q)|-5 or del(5q) 0|0|0|94|0|0|0 NO FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2887 -21946 FEMALE WHITE No NO No NO [Not Available] [Not Available] none [Not Available] Dead [Not Available] [Not Available] Bone marrow aspirate 2009 60 87 M1 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Negative|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Negative|CD34 Positive|CD45 Positive|CD56 Negative|CD117 Positive|HLA-DR Positive|Other CD Negative 80 47 9 50 65 0 0 0 0 4 0 0 31 0 0 0 0 YES 20 Intermediate/Normal del(7q) / 7q- [Not Available] YES YES PML-RAR|MLL|CBF-Beta|AML1-ETO|-7 or del(7q)|-5 or del(5q) 0|0|0|0|99|0 NO PML-RAR Negative|FLT3 Mutation Negative|[Not Evaluated]|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Positive|NPMc Negative YES 0 AB TCGA-AB-2889 -20150 MALE WHITE No NO No NO [Not Available] [Not Available] none [Not Available] Alive 304 [Not Applicable] Bone marrow aspirate 2009 55 52 M4 NA Not Tested|MPX Not Tested|NSE Not Tested|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Positive|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Not Tested 90 31 9 9 59 0 0 0 5 2 0 0 32 2 0 0 1 YES 20 Favorable inv(16) [Not Available] YES YES PML-RAR|MLL|CBF-Beta|AML1-ETO|+8|-7 or del(7q)|-5 or del(5q) 0|0|87|0|0|0|0 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2890 -25234 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] 0 Bone marrow aspirate 2009 69 60 M0 Undifferentiated MPX Negative|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Negative|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD 117 Not Tested|HLA-DR Not Tested|Other CD Not Tested 50 6 11 61 22 0 0 0 1 2 1 0 65 1 0 0 8 YES 20 Poor Normal [Not Available] YES NO -5 or del(5q) 0 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2891 -15400 MALE BLACK OR AFRICAN AMERICAN No NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] [Not Available] Bone marrow aspirate 2009 42 68 M1 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD 117 Not Tested|HLA-DR Positive|Other CD Positive 80 11 12 176 51 0 2 0 3 15 0 0 18 10 0 0 1 YES 20 Poor Complex - >= 3 distinct abnormalities [Not Available] YES YES PML-RAR|CBF-Beta|AML1-ETO|+8|-7 or del(7q)|-5 or del(5q)|Other 0|0|0|0|0|0|86 NO FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Positive|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2892 -15614 FEMALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 943 [Not Applicable] Bone marrow aspirate 2006 42 40 M4 MPX Positive|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD 117 Not Tested|HLA-DR Not Tested|Other CD Not Tested 90 38 10 12 16 0 0 0 0 12 4 2 20 34 0 8 4 YES 20 Favorable Normal|inv(16) [Not Available] YES YES BCR-ABL|PML-RAR|MLL|CBF-Beta 1|1|0|97 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Positive|NPMc Negative YES 0 AB TCGA-AB-2893 -16617 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] 212 Bone marrow aspirate 2006 45 95 M5 MPX Negative|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Positive|CD117 Positive|HLA-DR Not Tested|Other CD Positive 75 5 9 53 6 0 0 0 2 4 0 0 45 35 0 8 0 YES 20 Poor [Not Available] [Not Available] YES YES PML-RAR|MLL 0|86 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Positive|NPMc Negative YES 0 AB TCGA-AB-2894 -18323 FEMALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] 181 Bone marrow aspirate 2007 50 81 M5 MPX Negative|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Negative|CD45 Positive|CD56 Negative|CD117 Positive|HLA-DR Not Tested|Other CD Positive 90 7 10 136 10 0 3 0 5 7 2 0 64 4 0 0 5 YES 20 Poor Normal|del(7q) / 7q-|t(9;11) [Not Available] YES YES BCR-ABL|PML-RAR|MLL|CBF-Beta|TEL-AML 1|+8|-7 or del(7q) 0|0|74|0|0|0|76 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2895 -15310 FEMALE WHITE No NO Yes YES 2 6000 None [Not Available] Dead [Not Available] 153 Bone marrow aspirate 2009 41 92 M1 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Positive|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Not Tested 90 134 12 40 90 0 1 0 2 4 1 0 2 0 0 0 0 [Not Available] 0 [Not Available] [Not Available] [Not Available] YES NO PML-RAR|CBF-Beta|AML1-ETO 0|0|0 YES FLT3 Mutation Positive|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Positive YES 0 AB TCGA-AB-2897 -18413 FEMALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 243 [Not Applicable] Bone marrow aspirate 2009 50 90 M3 MPX Not Tested|NSE Not Tested|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Negative|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Negative|Other CD Not Tested 90 3 10 27 0 0 0 0 0 46 0.3 0.4 19 35 0 0 0 YES 20 Favorable Normal|t(15;17) and variants [Not Available] YES YES PML-RAR|CBF-Beta 98|0 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2898 -25326 FEMALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 393 [Not Applicable] Bone marrow aspirate 2009 69 42 M1 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD 117 Not Tested|HLA-DR Not Tested|Other CD Not Tested 90 10 7 12 32 0 0 0 0 5 0 0 22 1 0 0 40 YES 20 Poor 8 [Not Available] YES NO PML-RAR 0 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Positive|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2901 -10046 MALE BLACK OR AFRICAN AMERICAN No NO Yes YES 1 4000 None [Not Available] Alive 59 [Not Applicable] Bone marrow aspirate 2009 27 77 M2 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD 117 Not Tested|HLA-DR Not Tested|Other CD Not Tested 100 90 9 87 88 0 0 0 0 8 0 0 1 3 0 0 0 YES 20 Poor Complex - >= 3 distinct abnormalities|+8 "21, 9(9;22)" YES YES PML-RAR|MLL|CBF-Beta|AML1-ETO|+8|-7 or del(7q)|-5 or del(5q)|Other 0|0|0|0|94|0|0|97 NO FLT3 Mutation Negative|IDH1 R132 Positive|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2903 -27971 FEMALE WHITE No NO Yes YES 2 4000 [Not Available] [Not Available] Dead [Not Available] 0 Bone marrow aspirate 2006 76 99 M1 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Not Tested|CD34 Not Tested|CD45 Not Tested|CD56 Positive|CD117 Positive|HLA-DR Not Tested|Other CD Not Tested 90 297 11 40 98 0 0 0 0 1 0 0 1 0 0 0 0 YES 20 Intermediate/Normal Normal [Not Available] YES NO PML-RAR|CBF-Beta|AML1-ETO 0|0|0 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Positive YES 0 AB TCGA-AB-2904 -23833 MALE WHITE No NO No NO 0 0 None [Not Available] Dead [Not Available] 517 Bone marrow aspirate 2008 65 83 M0 Undifferentiated MPX Negative|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Negative 60 1 10 94 0 0 0 0 0 3 0 0 94 0 0 0 3 YES 20 Poor Complex - >= 3 distinct abnormalities|del(5q) / 5q-|+8 [Not Available] YES YES MLL|+8|Other 19|87|82 YES FLT3 Mutation Positive|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2908 -29769 MALE WHITE Yes NO No NO 0 0 No Exposure [Not Available] Dead [Not Available] 31 Bone marrow aspirate 2008 81 46 M2 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Negative|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Not Tested 60 2 10 39 0 0 2 0 5 20 0 4 59 5 0 0 5 YES 20 Poor Complex - >= 3 distinct abnormalities|del(5q) / 5q- 21 YES YES CBF-Beta|AML1-ETO|+8|-5 or del(5q)|Other 0|0|0|100|87 NO FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2910 -22311 FEMALE WHITE No NO Yes YES 1 2000 None [Not Available] Dead [Not Available] 0 Bone marrow aspirate 2008 61 71 M5 MPX Positive|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Positive|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Not Tested|CD45 Not Tested|CD56 Positive|CD 117 Not Tested|HLA-DR Positive|Other CD Positive 70 35 12 35 55 1 1 3 0 5 0 0 14 21 0 0 0 YES 20 Intermediate/Normal Normal Yes NO NO PML-RAR|MLL|CBF-Beta|AML1-ETO|+8 0|0|0|0|0 [Not Available] FLT3 Mutation Positive|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2911 -18689 FEMALE BLACK OR AFRICAN AMERICAN No NO Yes YES 1 2000 Benzene/other chemicals [Not Available] Alive 1186 [Not Applicable] Bone marrow aspirate 2006 51 39 M4 MPX Positive|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Not Tested|Other CD Negative 90 50 11 21 39 0 9 0 0 0 0 0 13 39 0 0 0 YES 20 Poor Normal|Complex - >= 3 distinct abnormalities [Not Available] YES YES BCR-ABL|PML-RAR|MLL 0|0|98 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Positive|NPMc Negative YES 0 AB TCGA-AB-2912 -23345 MALE WHITE No NO Yes YES 2 2000 None [Not Available] Dead [Not Available] 274 Bone marrow aspirate 2007 63 62 M4 MPX Negative|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Negative|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Negative|CD34 Positive|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Positive|Other CD Negative 90 18 8 148 9 0 3 0 0 20 0 0 20 34 0 9 1 YES 20 Poor 8 [Not Available] YES YES BCR-ABL|PML-RAR|MLL|CBF-Beta|AML1-ETO|+8|-7 or del(7q) 0|0|0|0|0|73|0 NO FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2913 -22553 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 1216 [Not Applicable] Bone marrow aspirate 2006 61 95 M0 Undifferentiated MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Positive|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Not Tested [Not Available] 62 13 25 86 0 0 0 0 3 0 0 8 1 0 0 2 YES 20 Poor Normal|+8 [Not Available] YES NO BCR-ABL|PML-RAR|MLL|CBF-Beta|-7 or del(7q) 0|0|0|0|0 [Not Available] FLT3 Mutation Positive|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Positive YES 0 AB TCGA-AB-2914 -8280 FEMALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 792 [Not Applicable] Bone marrow aspirate 2007 22 55 M2 MPX Positive|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Not Tested 70 52 11 149 70 0 1 0 1 5 0 0 9 14 0 0 0 YES 20 Favorable Normal|inv(16) [Not Available] YES YES BCR-ABL|PML-RAR|CBF-Beta|AML1-ETO 0|0|83|0 YES FLT3 Mutation Positive|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2915 -26968 FEMALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] 0 Bone marrow aspirate 2009 73 11 M2 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Not Tested|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Not Tested 40 15 9 64 11 0 0 0 1 74 0 0 3 11 0 0 0 YES 20 Poor Complex - >= 3 distinct abnormalities [Not Available] YES YES PML-RAR|MLL|CBF-Beta|+8|-7 or del(7q)|-5 or del(5q) 0|0|0|0|43|0 YES FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2916 -17866 FEMALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 882 [Not Applicable] Bone marrow aspirate 2007 48 51 M4 MPX Positive|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Positive|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Positive 80 12 9 351 5 0 5 0 4 39 0 0 15 32 0 0 0 YES 20 Intermediate/Normal [Not Available] [Not Available] NO [Not Available] [Not Available] [Not Available] NO FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2917 -15128 FEMALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 1216 [Not Applicable] Bone marrow aspirate 2006 41 42 M0 Undifferentiated MPX Negative|NSE Not Tested|TDT Not Tested|CD3 Negative|CD5 Positive|CD7 Positive|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Not Tested|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Not Tested 80 48 12 71 74 2 2 1 2 6 0 1 3 9 0 0 0 YES 21 Poor Normal|Complex - >= 3 distinct abnormalities|del(7q) / 7q- [Not Available] NO [Not Available] [Not Available] [Not Available] [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Positive|NPMc Negative YES 0 AB TCGA-AB-2918 -17198 FEMALE WHITE No NO Yes YES 2 4000 None [Not Available] Dead [Not Available] [Not Available] Bone marrow aspirate 2009 47 77 M1 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD 117 Not Tested|HLA-DR Not Tested|Other CD Negative [Not Available] 81 10 53 79 0 1 0 0 4 1 0 10 4 0 0 0 YES 20 Poor 8 [Not Available] YES YES PML-RAR|MLL|CBF-Beta|AML1-ETO|+8|-7 or del(7q)|-5 or del(5q) 0|0|0|0|88|0|0 YES FLT3 Mutation Positive|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2919 -19724 FEMALE WHITE No NO Yes YES 2 2000 None [Not Available] Alive 61 [Not Applicable] Bone marrow aspirate 2009 54 72 M1 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Negative|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Negative|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Negative|Other CD Negative 90 13 9 22 90 0 0 0 0 1 0 0 9 0 0 0 0 YES 20 Intermediate/Normal Normal [Not Available] YES NO PML-RAR|MLL|CBF-Beta|AML1-ETO|+8|-7 or del(7q)|-5 or del(5q) 0|0|0|0|0|0|0 YES BCR-ABL Negative|FLT3 Mutation Positive|IDH1 R132 Positive|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Positive YES 0 AB TCGA-AB-2920 -16071 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] 366 Bone marrow aspirate 2007 44 39 M2 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Not Tested|Other CD Negative 80 35 10 35 83 0 0 0 0 4 0 0 11 2 0 0 0 YES 20 Poor Normal|Complex - >= 3 distinct abnormalities|del(7q) / 7q-|+8 [Not Available] YES YES +8|Other 99|95 NO FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2921 -20454 FEMALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] [Not Available] Bone marrow aspirate 2009 56 69 M4 MPX Positive|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Negative|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Positive|Other CD Negative 90 28 8 31 57 0 1 4 1 2 0 0 21 11 0 3 0 YES 20 Intermediate/Normal Normal [Not Available] YES NO PML-RAR|MLL|CBF-Beta|AML1-ETO|+8|-7 or del(7q)|-5 or del(5q) 0|0|0|0|0|0|0 YES BCR-ABL Negative|FLT3 Mutation Positive|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2924 -21825 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 90 [Not Applicable] Bone marrow aspirate 2009 59 75 M4 MPX Positive|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Positive|CD25 Not Tested|CD33 Not Tested|CD34 Not Tested|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Positive 90 30 9 18 17 0 0 1 0 21 0 1 12 34 0 14 0 YES 20 Intermediate/Normal Normal No YES NO BCR-ABL|PML-RAR|MLL|CBF-Beta|AML1-ETO|+8|-7 or del(7q)|-5 or del(5q) 0|0|0|0|0|0|0|0 YES BCR-ABL Negative|FLT3 Mutation Positive|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Positive YES 0 AB TCGA-AB-2928 -15890 FEMALE BLACK OR AFRICAN AMERICAN No NO Yes YES 3 9000 None [Not Available] Dead 59 [Not Available] Bone marrow aspirate 2010 43 87 M1 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Negative|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Negative|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Positive|Other CD Negative 90 172 10 32 91 0 0 0 0 0 0 0 9 0 0 0 [Not Available] YES 20 Poor del(7q) / 7q- [Not Available] YES YES -7 or del(7q) 98 YES PML-RAR Negative|FLT3 Mutation Positive|IDH1 R132 Positive|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2929 -26054 FEMALE WHITE Yes NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] 123 Bone marrow aspirate 2007 71 55 M0 Undifferentiated MPX Negative|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Negative [Not Available] 6 9 50 50 0 1 0 7 16 1 1 22 2 0 0 0 YES 20 Poor Normal|Complex - >= 3 distinct abnormalities|del(7q) / 7q- [Not Available] YES NO BCR-ABL|PML-RAR|MLL|CBF-Beta|AML1-ETO|+8 0|1|1|1|2|0 NO FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Positive|NPMc Negative YES 0 AB TCGA-AB-2930 -23011 FEMALE WHITE No [Not Available] No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] [Not Available] Bone marrow aspirate 2009 63 72 M2 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Positive|Other CD Negative 90 28 10 69 49 0 12 3 4 7 2 0 18 5 0 0 0 YES 20 Intermediate/Normal Normal [Not Available] YES NO PML-RAR|MLL|CBF-Beta|AML1-ETO|+8|-7 or del(7q)|-5 or del(5q) 0|0|0|0|0|0|0 YES FLT3 Mutation Positive|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2931 -27485 MALE WHITE Yes YES No NO [Not Available] [Not Available] [Not Available] [Not Available] Dead [Not Available] 0 Bone marrow aspirate 2007 75 76 M2 MPX Not Tested|NSE Not Tested|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Negative 90 98 8 31 80 2 0 0 0 4 0 0 9 2 0 0 3 YES 20 Intermediate/Normal [Not Available] [Not Available] YES NO BCR-ABL|PML-RAR|CBF-Beta|AML1-ETO 0|0|0|0 YES FLT3 Mutation Positive|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2932 -22738 MALE WHITE Yes NO Yes YES 3 8000 None [Not Available] Alive 0 [Not Applicable] Bone marrow aspirate 2008 62 85 M5 MPX Positive|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Negative|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Positive|Other CD Positive 90 59 7 20 22 0 0 0 0 5 0 0 11 59 0 3 0 YES 20 Intermediate/Normal Normal [Not Available] YES NO BCR-ABL|PML-RAR|MLL|CBF-Beta|AML1-ETO|+8|-7 or del(7q) 0|0|0|0|0|0|0 YES BCR-ABL Negative|PML-RAR Negative|FLT3 Mutation Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Positive YES 0 AB TCGA-AB-2934 -23956 MALE WHITE No NO Yes YES 2 5000 [Not Available] [Not Available] Alive 28 [Not Applicable] Bone marrow aspirate 2010 65 79 M1 MPX Positive|NSE Negative|TDT Positive|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Not Tested 90 68 9 142 84 0 0 0 0 2 0 0 5 9 0 0 0 YES 15 Intermediate/Normal Normal [Not Available] YES NO PML-RAR|MLL|CBF-Beta|AML1-ETO|+8|-7 or del(7q)|-5 or del(5q) 0|0|0|0|0|0|0 YES BCR-ABL Negative|FLT3 Mutation Positive|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2935 -24349 MALE WHITE Yes NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] 61 Bone marrow aspirate 2007 66 81 M4 MPX Not Tested|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Negative|Other CD Not Tested 40 2 8 37 12 3 1 3 8 14 0 0 33 25 0 0 1 YES 20 Poor del(5q) / 5q-|del(7q) / 7q- [Not Available] YES YES -7 or del(7q) 45 NO BCR-ABL Negative|FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2936 -22280 FEMALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 59 [Not Applicable] Bone marrow aspirate 2010 61 50 M0 Undifferentiated MPX Negative|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Negative|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Negative|CD34 Positive|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Not Tested|Other CD Negative 70 2 9 79 14 0 0 0 1 26 1 0 49 9 0 0 0 YES 20 Intermediate/Normal Normal [Not Available] YES NO CBF-Beta|AML1-ETO|-5 or del(5q) 0|0|0 NO FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2937 -13149 FEMALE WHITE No NO Yes YES 3 2000 None [Not Available] Dead [Not Available] 215 Bone marrow aspirate 2007 36 81 M1 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Not Tested|CD34 Positive|CD45 Not Tested|CD56 Positive|CD117 Positive|HLA-DR Positive|Other CD Not Tested 80 43 9 66 86 0 3 0 0 2 0 0 9 0 0 0 0 YES 20 Favorable t(8;21) [Not Available] YES YES PML-RAR|CBF-Beta|AML1-ETO|+8|-7 or del(7q) 0|0|100|0|0 NO FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2939 -26512 MALE WHITE Yes NO No NO [Not Available] [Not Available] None [Not Available] Alive 455 [Not Applicable] Bone marrow aspirate 2008 72 88 M1 NA Not Tested|MPX Not Tested|NSE Not Tested|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD 117 Not Tested|HLA-DR Not Tested|Other CD Not Tested 90 38 10 31 18 0 0 1 0 6 3 0 23 1 0 0 48 YES 20 Poor Complex - >= 3 distinct abnormalities|del(5q) / 5q- [Not Available] YES YES -5 or del(5q)|Other 100|34 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2940 -12876 MALE WHITE No NO Yes YES 3 4000 None [Not Available] Dead [Not Available] [Not Available] Bone marrow aspirate 2006 35 34 M2 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Not Tested 90 34 8 88 40 3 3 1 11 3 9 1 15 9 0 0 5 YES 19 Intermediate/Normal Normal 21 YES YES BCR-ABL|AML1-ETO|Other 3|0|50 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2941 -26998 MALE WHITE Yes NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] 0 Bone marrow aspirate 2006 73 90 Not Classified MPX Positive|NSE Not Tested|TDT Not Tested|CD3 Negative|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Negative|CD23 Not Tested|CD25 Not Tested|CD33 Not Tested|CD34 Not Tested|CD45 Positive|CD56 Negative|CD117 Positive|HLA-DR Not Tested|Other CD Positive 90 59 9 11 0 0 0 0 0 94 0 0 4 1 0 0 0 YES 20 Poor Normal|del(5q) / 5q-|del(7q) / 7q- t(9;22) YES YES BCR-ABL|CBF-Beta|-7 or del(7q) 88|35|56 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2942 -24776 FEMALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 641 [Not Applicable] Bone marrow aspirate 2008 67 69 M4 MPX Positive|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Positive|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Not Tested 50 37 9 15 61 0 0 0 0 4 1 0 13 20 0 0 1 YES 20 Favorable Normal|inv(16) [Not Available] YES YES CBF-Beta 85 NO FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2943 -25568 FEMALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] [Not Available] Bone marrow aspirate 2010 70 32 M1 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Positive|CD117 Positive|HLA-DR Positive|Other CD Not Tested 50 1 8 82 6 0 2 0 0 8 2 0 72 4 0 6 0 YES 20 Poor Complex - >= 3 distinct abnormalities|del(5q) / 5q- [Not Available] NO [Not Available] [Not Available] [Not Available] NO FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2944 -17622 MALE WHITE No NO Yes YES 3 9000 None [Not Available] Dead [Not Available] [Not Available] Bone marrow aspirate 2010 48 92 M0 Undifferentiated MPX Negative|NSE Negative|TDT Positive|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Not Tested 100 111 9 53 87 0 0 0 1 1 2 0 8 1 0 0 0 YES 5 Poor [Not Available] [Not Available] YES YES PML-RAR|MLL|CBF-Beta|AML1-ETO|+8|-7 or del(7q)|-5 or del(5q) 0|0|0|0|0|98|0 YES BCR-ABL Positive|FLT3 Mutation Positive|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2946 -15156 MALE WHITE No NO Yes YES 4 10000 None [Not Available] Alive [Not Available] [Not Applicable] Bone marrow aspirate 2010 41 47 M2 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Positive|Other CD Positive 55 43 9 51 62 0 0 0 0 3 3 0 8 22 0 0 2 [Not Available] [Not Available] Intermediate/Normal [Not Available] [Not Available] [Not Available] [Not Available] [Not Available] [Not Available] [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2949 -21336 MALE WHITE No NO Yes YES 2 5000 None [Not Available] Alive 699 [Not Applicable] Bone marrow aspirate 2008 58 59 M0 Undifferentiated MPX Positive|NSE Negative|TDT Negative|CD3 Negative|CD5 Positive|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Negative|CD34 Positive|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Positive|Other CD Not Tested 85 47 10 55 72 0 1 1 1 4 0 0 13 6 0 2 0 YES 20 Poor Complex - >= 3 distinct abnormalities|del(7q) / 7q-|+8 [Not Available] YES YES PML-RAR|CBF-Beta|Other 0|0|58 NO FLT3 Mutation Negative|IDH1 R132 Positive|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2950 -12693 FEMALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 306 [Not Applicable] Bone marrow aspirate 2008 34 57 M2 MPX Positive|NSE Not Tested|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Not Tested 90 14 9 40 59 3 5 2 5 3 0 0 19 2 0 0 2 YES 20 Favorable t(8;21) [Not Available] YES YES BCR-ABL|AML1-ETO|Other 0|96|95 NO FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2952 -22188 FEMALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] 31 Bone marrow aspirate 2007 60 62 M1 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Positive|CD117 Positive|HLA-DR Positive|Other CD Not Tested 80 16 8 90 29 0 4 1 11 22 1 6 9 14 0 0 0 YES 20 Poor Complex - >= 3 distinct abnormalities|del(5q) / 5q-|del(7q) / 7q-|+8 [Not Available] YES YES BCR-ABL|PML-RAR|+8 0|0|38 NO FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2954 -20211 FEMALE WHITE No NO No NO [Not Available] [Not Available] [Not Available] [Not Available] Alive 1492 [Not Applicable] Bone marrow aspirate 2006 55 54 M4 MPX Positive|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Positive|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Positive 90 114 9 37 24 6 4 0 0 1 1 0 4 46 0 13 0 YES 20 Intermediate/Normal Normal [Not Available] YES YES Other 96 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2956 -22523 MALE WHITE No NO Yes YES 2 32000 None [Not Available] Dead [Not Available] 183 Bone marrow aspirate 2007 61 89 M5 MPX Positive|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Negative|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Negative|CD45 Not Tested|CD56 Positive|CD117 Positive|HLA-DR Positive|Other CD Positive 90 8 7 36 0 0 0 0 0 12 0 0 31 57 0 0 0 YES 20 Intermediate/Normal Normal|t(9;11) [Not Available] YES YES BCR-ABL|MLL|CBF-Beta|AML1-ETO|+8|-7 or del(7q)|Other 0|97|1|1|1|1|4 NO FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2964 -21184 FEMALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 1277 [Not Applicable] Bone marrow aspirate 2006 58 64 M1 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Not Tested|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Not Tested 80 3 6 35 61 0 0 0 0 5 0 0 34 0 0 0 0 YES 19 Intermediate/Normal Normal [Not Available] YES NO PML-RAR 0 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2967 -21214 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 1035 [Not Applicable] Bone marrow aspirate 2007 58 58 M4 MPX Positive|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Negative|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Negative|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Positive|Other CD Not Tested 90 20 9 121 10 0 5 0 5 45 1 0 17 17 0 0 0 YES 20 Intermediate/Normal Normal [Not Available] YES NO CBF-Beta 0 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Positive YES 0 AB TCGA-AB-2969 -20331 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 1127 [Not Applicable] Bone marrow aspirate 2006 55 97 M5 MPX Positive|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Not Tested|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Positive [Not Available] 73 8 17 8 0 2 1 0 1 1 0 13 50 0 0 8 YES 20 Intermediate/Normal Normal [Not Available] YES NO BCR-ABL|PML-RAR|MLL 3|3|0 [Not Available] FLT3 Mutation Positive|IDH1 R132 Positive|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Positive YES 0 AB TCGA-AB-2972 -30134 FEMALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] 30 Bone marrow aspirate 2007 82 53 M2 MPX Not Tested|NSE Not Tested|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Not Tested|CD34 Positive|CD45 Positive|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Not Tested 70 1 11 30 25 0 2 0 0 24 0 0 42 5 0 0 2 YES 20 Intermediate/Normal Normal [Not Available] YES NO -5 or del(5q) 0 NO FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Positive YES 0 AB TCGA-AB-2975 -20057 MALE BLACK OR AFRICAN AMERICAN No NO No NO [Not Available] [Not Available] None [Not Available] Dead [Not Available] [Not Available] Bone marrow aspirate 2007 54 67 M2 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Not Tested 90 68 8 87 71 2 4 0 1 1 0 0 18 3 0 0 0 YES 19 Intermediate/Normal Normal [Not Available] YES NO BCR-ABL|PML-RAR|MLL|CBF-Beta|AML1-ETO|+8|-7 or del(7q)|Other 2|1|0|0|0|1|0|0 NO PML-RAR Negative|FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2978 -22402 FEMALE WHITE No YES No NO 0 0 none [Not Available] Alive 699 [Not Applicable] Bone marrow aspirate 2008 61 43 M2 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Negative|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Positive|Other CD Negative 90 10 10 140 32 0 0 0 0 22 4 0 27 15 0 0 0 YES 20 Intermediate/Normal Normal [Not Available] NO [Not Available] [Not Available] [Not Available] NO FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2979 -11262 FEMALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 671 [Not Applicable] Bone marrow aspirate 2008 30 86 M1 MPX Positive|NSE Not Tested|TDT Not Tested|CD3 Not Tested|CD5 Negative|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Positive|Other CD Negative [Not Available] 23 10 59 88 0 0 0 0 6 0 0 6 0 0 0 0 YES 20 Intermediate/Normal Normal No YES NO BCR-ABL|PML-RAR|AML1-ETO 0|0|0 NO FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2980 -18506 MALE WHITE No NO No NO [Not Available] [Not Available] none [Not Available] Alive 699 [Not Applicable] Bone marrow aspirate 2008 50 74 M3 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Negative|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Negative|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Negative|Other CD Negative 90 1 10 58 10 0 0 0 2 16 0 0 68 2 0 0 2 YES 20 Favorable t(15;17) and variants [Not Available] YES YES PML-RAR|CBF-Beta 96|0 YES PML-RAR Positive|FLT3 Mutation Positive|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2981 -13027 FEMALE WHITE No [Not Available] Yes YES 2 4000 [Not Available] [Not Available] Alive 487 [Not Applicable] Bone marrow aspirate 2008 35 87 M5 MPX Negative|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Negative|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Negative|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Positive|Other CD Negative 100 72 9 19 8 0 0 1 0 0 0 0 21 29 0 41 0 YES 20 Intermediate/Normal Normal [Not Available] YES NO PML-RAR|MLL|CBF-Beta 1|0|0 YES FLT3 Mutation Positive|IDH1 R132 Positive|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Positive YES 0 AB TCGA-AB-2984 -14123 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 1157 [Not Applicable] Bone marrow aspirate 2006 38 86 M1 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Negative|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Negative|Other CD Negative 90 40 9 19 97 0 0 0 0 0 0 1 2 0 0 0 0 YES 20 Intermediate/Normal Normal [Not Available] YES NO PML-RAR|MLL|TEL-AML 1 2|2|2 [Not Available] FLT3 Mutation Negative|IDH1 R132 Positive|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Positive|NPMc Positive YES 0 AB TCGA-AB-2985 -29890 FEMALE WHITE No NO Yes YES 2 3000 None [Not Available] Dead [Not Available] 273 Bone marrow aspirate 2008 81 53 M5 MPX Positive|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Negative|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Positive 70 12 9 61 7 0 0 0 1 1 0 0 20 67 0 4 0 YES 20 Intermediate/Normal Normal [Not Available] YES NO PML-RAR|CBF-Beta|-5 or del(5q) 0|0|0 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Positive|NPMc Negative YES 0 AB TCGA-AB-2987 -27667 FEMALE WHITE No NO Yes YES 4 14000 None [Not Available] Dead [Not Available] 184 Bone marrow aspirate 2008 75 41 M5 MPX Negative|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Positive|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Negative|CD45 Not Tested|CD56 Not Tested|CD 117 Not Tested|HLA-DR Not Tested|Other CD Positive 80 7 9 11 0 0 0 0 0 2 0 1 59 38 0 0 0 YES 20 Intermediate/Normal Normal|del(7q) / 7q- [Not Available] YES NO BCR-ABL|PML-RAR|MLL|CBF-Beta|AML1-ETO|+8|-7 or del(7q) 0|0|0|0|0|0|0 NO FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Positive|NPMc Positive YES 0 AB TCGA-AB-2990 -18962 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 457 [Not Applicable] Bone marrow aspirate 2008 51 85 M1 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Negative|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Negative|Other CD Negative 90 64 10 45 85 0 0 0 1 3 0 0 9 0 0 2 0 YES 20 Intermediate/Normal Normal [Not Available] YES NO PML-RAR|MLL|CBF-Beta|AML1-ETO|+8|-7 or del(7q) 0|0|0|0|0|0 NO FLT3 Mutation Negative|IDH1 R132 Positive|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Positive YES 0 AB TCGA-AB-2991 -14885 FEMALE WHITE No [Not Available] No NO 0 0 None [Not Available] Alive 1826 [Not Applicable] Bone marrow aspirate 2004 40 0 M3 MPX Positive|NSE Not Tested|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Not Tested 95 [Not Available] 8 34 0 0 0 0 0 5 0 0 90 5 0 0 0 YES 20 Favorable +8|t(15;17) and variants No YES YES BCR-ABL|PML-RAR 4|78 [Not Available] FLT3 Mutation Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2993 -21124 FEMALE WHITE No [Not Available] Yes YES 2 4500 [Not Available] [Not Available] Dead [Not Available] 761 Bone marrow aspirate 2004 57 6 M4 MPX Positive|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Negative|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Negative|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Negative|Other CD Negative 90 103 10 82 91 0 0 0 2 6 0 0 1 0 1 0 0 YES 20 Intermediate/Normal Normal no YES YES PML-RAR|CBF-Beta 0|0 [Not Available] [Not Available] YES 0 AB TCGA-AB-2994 -9436 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 1798 [Not Applicable] Bone marrow aspirate 2005 25 91 M3 MPX Positive|NSE Positive|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Not Tested|CD34 Not Tested|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Not Tested 100 8 10 18 7 56 4 0 0 11 1 2 15 3 0 0 1 YES 20 Favorable t(15;17) and variants No YES YES PML-RAR 93 [Not Available] FLT3 Mutation Positive|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2995 -23164 MALE WHITE No [Not Available] No NO 0 0 [Not Available] [Not Available] Alive 1551 [Not Applicable] Bone marrow aspirate 2005 63 0 M2 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Not Tested|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Not Tested 20 1 11 43 0 0 0 0 0 16 2 0 78 2 2 0 0 YES 20 Intermediate/Normal Normal no NO [Not Available] [Not Available] [Not Available] [Not Available] IDH1 R132 Negative YES 0 AB TCGA-AB-2996 -27364 MALE WHITE Yes [Not Available] No NO 0 0 None [Not Available] Alive 1581 [Not Applicable] Bone marrow aspirate 2005 74 2 M2 MPX Positive|NSE Not Tested|TDT Negative|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Not Tested|CD34 Positive|CD45 Positive|CD56 Not Tested|CD117 Positive|HLA-DR Positive|Other CD Not Tested 70 3 9 118 2 0 0 0 0 46 0 0 44 6 2 0 0 YES 20 Intermediate/Normal Normal [Not Available] NO [Not Available] [Not Available] [Not Available] [Not Available] IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2998 -24837 FEMALE WHITE No NO Yes YES 4 14000 None [Not Available] Dead [Not Available] 31 Bone marrow aspirate 2008 68 85 M3 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Negative|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Negative|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Negative|CD45 Not Tested|CD56 Negative|CD117 Positive|HLA-DR Negative|Other CD Not Tested 100 29 10 73 32 8 10 0 0 1 1 0 4 24 0 17 3 YES 20 Favorable t(15;17) and variants [Not Available] YES YES PML-RAR 100 YES PML-RAR Positive|FLT3 Mutation Positive|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-2999 -22980 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 1735 [Not Applicable] Bone marrow aspirate 2004 62 82 M3 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Negative|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Negative|Other CD Not Tested 90 1 9 15 11 0 1 0 2 10 0 0 65 5 0 0 6 YES 20 Favorable Normal|t(15;17) and variants [Not Available] YES YES PML-RAR 93 NO FLT3 Mutation Positive|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-3000 -9251 MALE WHITE No NO Yes YES 2 4000 None [Not Available] Alive 1249 [Not Applicable] Bone marrow aspirate 2006 25 56 M2 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Positive|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Not Tested 90 99 9 60 71 2 5 3 1 6 0 0 8 4 0 0 0 YES 20 Intermediate/Normal Normal [Not Available] NO [Not Available] [Not Available] [Not Available] [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-3005 -16528 MALE WHITE No [Not Available] No NO 0 0 None [Not Available] Alive 2100 [Not Applicable] Bone marrow aspirate 2003 45 0 M5 MPX Not Tested|NSE Not Tested|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Not Tested|CD45 Not Tested|CD56 Not Tested|CD 117 Not Tested|HLA-DR Not Tested|Other CD Positive 80 2 13 257 0 0 0 2 3 20 12 0 54 9 0 0 0 YES 20 Intermediate/Normal Normal [Not Available] YES NO MLL 0 [Not Available] IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-3006 -22464 MALE WHITE No [Not Available] No NO 0 0 [Not Available] [Not Available] Dead [Not Available] 485 Bone marrow aspirate 2006 61 14 M1 MPX Positive|NSE Not Tested|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Negative|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Not Tested|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Not Tested|Other CD Not Tested 60 3 14 61 14 0 0 0 21 20 2 0 48 2 0 0 15 YES 20 Intermediate/Normal Normal [Not Available] YES NO PML-RAR|CBF-Beta|AML1-ETO 3|0|2 [Not Available] [Not Available] YES 0 AB TCGA-AB-3007 -13029 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 1581 [Not Applicable] Bone marrow aspirate 2005 35 90 M3 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Negative|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Negative|Other CD Not Tested 90 2 12 12 7 1 1 0 5 34 1 0 50 1 0 0 0 YES 20 Favorable Normal|del(7q) / 7q-|+8|t(15;17) and variants NO YES YES PML-RAR|CBF-Beta|-7 or del(7q) 15|0|96 [Not Available] FLT3 Mutation Positive|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB TCGA-AB-3011 -7916 FEMALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 1885 [Not Applicable] Bone marrow aspirate 2005 21 91 M1 MPX Positive|NSE Negative|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Negative|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Negative|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Negative|Other CD Not Tested 95 8 8 52 83 0 0 0 1 1 0 0 14 1 0 0 0 YES 20 Intermediate/Normal Normal [Not Available] YES NO PML-RAR|MLL|TEL-AML 1 0|1|1 [Not Available] FLT3 Mutation Negative|IDH1 R132 Positive|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Positive YES 0 AB TCGA-AB-3012 -19543 MALE WHITE No NO No NO [Not Available] [Not Available] None [Not Available] Alive 1887 [Not Applicable] Bone marrow aspirate 2004 53 42 M3 MPX Positive|NSE Not Tested|TDT Not Tested|CD3 Not Tested|CD5 Not Tested|CD7 Not Tested|CD10 Not Tested|CD14 Not Tested|CD15 Not Tested|CD19 Not Tested|CD20 Not Tested|CD23 Not Tested|CD25 Not Tested|CD33 Positive|CD34 Negative|CD45 Not Tested|CD56 Not Tested|CD117 Positive|HLA-DR Negative|Other CD Not Tested 90 1 9 46 29 5 2 0 0 10 1 0 50 2 0 0 1 YES 20 Favorable t(15;17) and variants No YES YES PML-RAR 95 [Not Available] FLT3 Mutation Negative|IDH1 R132 Negative|IDH1 R140 Negative|IDH1 R172 Negative|Activating RAS Negative|NPMc Negative YES 0 AB