Table 6S. Top 20 GO terms and enriched pathways of the 131 mRNAs in ME1 module							
Category	ID	Name	Q-value FDR B&H	Hit Gene Number	Hit Percentage	Hit Count in Genome	Hit in Query List
Biological Process	GO:0001775	cell activation	4.40E-22	53	40.46%	1779	"TARM1,AMPD3,ADGRG3,STBD1,PGLYRP1,BTNL8,CD177,ABCA13,FOLR3,ANXA3,CAMP,CEACAM3,CEACAM8,OLFM4,GPR84,CEACAM6,DGKG,CRISP3,CST7,MUC5B,TLR9,CHI3L1,CHIT1,WLS,IL18RAP,CXCL1,OLR1,SLC2A3,PDXK,CEACAM1,ARG1,MMP25,PRAM1,S100P,RETN,FCAR,BPI,CLEC4D,HP,PTX3,KLF5,CYSTM1,QPCT,ELANE,GCA,LTF,CKAP4,MMP8,MMP9,CXCL6,PADI2,KLRC1,KLRC2"
Biological Process	GO:0045321	leukocyte activation	1.03E-21	50	38.17%	1584	"TARM1,AMPD3,ADGRG3,STBD1,PGLYRP1,BTNL8,CD177,ABCA13,FOLR3,ANXA3,CAMP,CEACAM3,CEACAM8,OLFM4,GPR84,CEACAM6,CRISP3,CST7,MUC5B,TLR9,CHI3L1,CHIT1,IL18RAP,CXCL1,OLR1,SLC2A3,PDXK,CEACAM1,ARG1,MMP25,PRAM1,S100P,RETN,FCAR,BPI,CLEC4D,HP,PTX3,CYSTM1,QPCT,ELANE,GCA,LTF,CKAP4,MMP8,MMP9,CXCL6,PADI2,KLRC1,KLRC2"
Biological Process	GO:0002252	immune effector process	1.18E-21	49	37.40%	1516	"TARM1,AMPD3,ADGRG3,STBD1,PGLYRP1,CD177,ABCA13,FOLR3,ANXA3,CAMP,CEACAM3,CEACAM8,OLFM4,GPR84,CEACAM6,CRISP3,TLR9,CHI3L1,CHIT1,IL18RAP,CXCL1,OLR1,SLC2A3,PDXK,CEACAM1,ARG1,MMP25,DEFA3,PRAM1,S100P,RETN,FCAR,BPI,CLEC4D,HP,PTX3,IFIT1B,CYSTM1,QPCT,ELANE,GCA,LTF,CKAP4,MMP8,MMP9,CXCL6,PADI2,KLRC1,KLRC2"
Biological Process	GO:0046903	secretion	1.22E-18	49	37.40%	1787	"NRG1,TARM1,AMPD3,ADGRG3,STBD1,TRPA1,PGLYRP1,CD177,ABCA13,SGK1,FOLR3,PPFIA4,ANXA3,CAMP,CEACAM3,CEACAM8,OLFM4,GPR84,CEACAM6,CRISP3,CHI3L1,CHIT1,WLS,CXCL1,OLR1,SLC2A3,PDXK,CEACAM1,ARG1,MMP25,PRAM1,S100P,RETN,FCAR,BPI,CLEC4D,HP,PTX3,CYSTM1,QPCT,ELANE,GCA,CYP4F3,LTF,CKAP4,MMP8,MMP9,PADI2,KLRC2"
Biological Process	GO:0002274	myeloid leukocyte activation	1.85E-32	47	35.88%	761	"TARM1,AMPD3,ADGRG3,STBD1,PGLYRP1,CD177,ABCA13,FOLR3,ANXA3,CAMP,CEACAM3,CEACAM8,OLFM4,GPR84,CEACAM6,CRISP3,CST7,MUC5B,TLR9,CHI3L1,CHIT1,IL18RAP,CXCL1,OLR1,SLC2A3,PDXK,CEACAM1,ARG1,MMP25,PRAM1,S100P,RETN,FCAR,BPI,CLEC4D,HP,PTX3,CYSTM1,QPCT,ELANE,GCA,LTF,CKAP4,MMP8,MMP9,CXCL6,PADI2"
Biological Process	GO:0002443	leukocyte mediated immunity	5.53E-27	47	35.88%	1017	"TARM1,AMPD3,ADGRG3,STBD1,PGLYRP1,CD177,ABCA13,FOLR3,ANXA3,CAMP,CEACAM3,CEACAM8,OLFM4,GPR84,CEACAM6,CRISP3,TLR9,CHI3L1,CHIT1,IL18RAP,CXCL1,OLR1,SLC2A3,PDXK,CEACAM1,ARG1,MMP25,PRAM1,S100P,RETN,FCAR,BPI,CLEC4D,HP,PTX3,CYSTM1,QPCT,ELANE,GCA,LTF,CKAP4,MMP8,MMP9,CXCL6,PADI2,KLRC1,KLRC2"
Biological Process	GO:0032940	secretion by cell	7.70E-19	47	35.88%	1607	"NRG1,TARM1,AMPD3,ADGRG3,STBD1,TRPA1,PGLYRP1,CD177,ABCA13,FOLR3,PPFIA4,ANXA3,CAMP,CEACAM3,CEACAM8,OLFM4,GPR84,CEACAM6,CRISP3,CHI3L1,CHIT1,WLS,CXCL1,OLR1,SLC2A3,PDXK,CEACAM1,ARG1,MMP25,PRAM1,S100P,RETN,FCAR,BPI,CLEC4D,HP,PTX3,CYSTM1,QPCT,ELANE,GCA,LTF,CKAP4,MMP8,MMP9,PADI2,KLRC2"
Biological Process	GO:0140352	export from cell	2.84E-18	47	35.88%	1662	"NRG1,TARM1,AMPD3,ADGRG3,STBD1,TRPA1,PGLYRP1,CD177,ABCA13,FOLR3,PPFIA4,ANXA3,CAMP,CEACAM3,CEACAM8,OLFM4,GPR84,CEACAM6,CRISP3,CHI3L1,CHIT1,WLS,CXCL1,OLR1,SLC2A3,PDXK,CEACAM1,ARG1,MMP25,PRAM1,S100P,RETN,FCAR,BPI,CLEC4D,HP,PTX3,CYSTM1,QPCT,ELANE,GCA,LTF,CKAP4,MMP8,MMP9,PADI2,KLRC2"
Biological Process	GO:0016050	vesicle organization	3.46E-14	45	34.35%	1924	"NRG1,TARM1,AMPD3,ADGRG3,STBD1,PGLYRP1,CD177,ABCA13,FOLR3,ANXA3,CAMP,CEACAM3,CEACAM8,OLFM4,GPR84,CEACAM6,CRISP3,CHI3L1,CHIT1,CXCL1,OLR1,SLC2A3,PDXK,CEACAM1,TGFA,ARG1,MMP25,PRAM1,S100P,RETN,FCAR,BPI,CLEC4D,HP,PTX3,CYSTM1,QPCT,ELANE,GCA,LTF,CKAP4,MMP8,MMP9,PADI2,KLRC2"
Biological Process	GO:0042119	neutrophil activation	2.58E-35	44	33.59%	515	"TARM1,AMPD3,ADGRG3,STBD1,PGLYRP1,CD177,ABCA13,FOLR3,ANXA3,CAMP,CEACAM3,CEACAM8,OLFM4,GPR84,CEACAM6,CRISP3,CHI3L1,CHIT1,IL18RAP,CXCL1,OLR1,SLC2A3,PDXK,CEACAM1,ARG1,MMP25,PRAM1,S100P,RETN,FCAR,BPI,CLEC4D,HP,PTX3,CYSTM1,QPCT,ELANE,GCA,LTF,CKAP4,MMP8,MMP9,CXCL6,PADI2"
Biological Process	GO:0036230	granulocyte activation	2.76E-35	44	33.59%	524	"TARM1,AMPD3,ADGRG3,STBD1,PGLYRP1,CD177,ABCA13,FOLR3,ANXA3,CAMP,CEACAM3,CEACAM8,OLFM4,GPR84,CEACAM6,CRISP3,CHI3L1,CHIT1,IL18RAP,CXCL1,OLR1,SLC2A3,PDXK,CEACAM1,ARG1,MMP25,PRAM1,S100P,RETN,FCAR,BPI,CLEC4D,HP,PTX3,CYSTM1,QPCT,ELANE,GCA,LTF,CKAP4,MMP8,MMP9,CXCL6,PADI2"
Biological Process	GO:0002446	neutrophil mediated immunity	4.12E-34	43	32.82%	524	"TARM1,AMPD3,ADGRG3,STBD1,PGLYRP1,CD177,ABCA13,FOLR3,ANXA3,CAMP,CEACAM3,CEACAM8,OLFM4,GPR84,CEACAM6,CRISP3,CHI3L1,CHIT1,CXCL1,OLR1,SLC2A3,PDXK,CEACAM1,ARG1,MMP25,PRAM1,S100P,RETN,FCAR,BPI,CLEC4D,HP,PTX3,CYSTM1,QPCT,ELANE,GCA,LTF,CKAP4,MMP8,MMP9,CXCL6,PADI2"
Biological Process	GO:0043299	leukocyte degranulation	1.55E-32	43	32.82%	580	"TARM1,AMPD3,ADGRG3,STBD1,PGLYRP1,CD177,ABCA13,FOLR3,ANXA3,CAMP,CEACAM3,CEACAM8,OLFM4,GPR84,CEACAM6,CRISP3,CHI3L1,CHIT1,CXCL1,OLR1,SLC2A3,PDXK,CEACAM1,ARG1,MMP25,PRAM1,S100P,RETN,FCAR,BPI,CLEC4D,HP,PTX3,CYSTM1,QPCT,ELANE,GCA,LTF,CKAP4,MMP8,MMP9,PADI2,KLRC2"
Biological Process	GO:0002444	myeloid leukocyte mediated immunity	9.76E-32	43	32.82%	610	"TARM1,AMPD3,ADGRG3,STBD1,PGLYRP1,CD177,ABCA13,FOLR3,ANXA3,CAMP,CEACAM3,CEACAM8,OLFM4,GPR84,CEACAM6,CRISP3,CHI3L1,CHIT1,CXCL1,OLR1,SLC2A3,PDXK,CEACAM1,ARG1,MMP25,PRAM1,S100P,RETN,FCAR,BPI,CLEC4D,HP,PTX3,CYSTM1,QPCT,ELANE,GCA,LTF,CKAP4,MMP8,MMP9,CXCL6,PADI2"
Biological Process	GO:0002366	leukocyte activation involved in immune response	5.53E-27	43	32.82%	800	"TARM1,AMPD3,ADGRG3,STBD1,PGLYRP1,CD177,ABCA13,FOLR3,ANXA3,CAMP,CEACAM3,CEACAM8,OLFM4,GPR84,CEACAM6,CRISP3,CHI3L1,CHIT1,CXCL1,OLR1,SLC2A3,PDXK,CEACAM1,ARG1,MMP25,PRAM1,S100P,RETN,FCAR,BPI,CLEC4D,HP,PTX3,CYSTM1,QPCT,ELANE,GCA,LTF,CKAP4,MMP8,MMP9,PADI2,KLRC2"
Biological Process	GO:0002263	cell activation involved in immune response	6.22E-27	43	32.82%	804	"TARM1,AMPD3,ADGRG3,STBD1,PGLYRP1,CD177,ABCA13,FOLR3,ANXA3,CAMP,CEACAM3,CEACAM8,OLFM4,GPR84,CEACAM6,CRISP3,CHI3L1,CHIT1,CXCL1,OLR1,SLC2A3,PDXK,CEACAM1,ARG1,MMP25,PRAM1,S100P,RETN,FCAR,BPI,CLEC4D,HP,PTX3,CYSTM1,QPCT,ELANE,GCA,LTF,CKAP4,MMP8,MMP9,PADI2,KLRC2"
Biological Process	GO:0045055	regulated exocytosis	2.38E-25	43	32.82%	881	"TARM1,AMPD3,ADGRG3,STBD1,PGLYRP1,CD177,ABCA13,FOLR3,ANXA3,CAMP,CEACAM3,CEACAM8,OLFM4,GPR84,CEACAM6,CRISP3,CHI3L1,CHIT1,CXCL1,OLR1,SLC2A3,PDXK,CEACAM1,ARG1,MMP25,PRAM1,S100P,RETN,FCAR,BPI,CLEC4D,HP,PTX3,CYSTM1,QPCT,ELANE,GCA,LTF,CKAP4,MMP8,MMP9,PADI2,KLRC2"
Biological Process	GO:0006887	exocytosis	5.68E-23	43	32.82%	1015	"TARM1,AMPD3,ADGRG3,STBD1,PGLYRP1,CD177,ABCA13,FOLR3,ANXA3,CAMP,CEACAM3,CEACAM8,OLFM4,GPR84,CEACAM6,CRISP3,CHI3L1,CHIT1,CXCL1,OLR1,SLC2A3,PDXK,CEACAM1,ARG1,MMP25,PRAM1,S100P,RETN,FCAR,BPI,CLEC4D,HP,PTX3,CYSTM1,QPCT,ELANE,GCA,LTF,CKAP4,MMP8,MMP9,PADI2,KLRC2"
Biological Process	GO:0140029	exocytic process	5.68E-23	43	32.82%	1015	"TARM1,AMPD3,ADGRG3,STBD1,PGLYRP1,CD177,ABCA13,FOLR3,ANXA3,CAMP,CEACAM3,CEACAM8,OLFM4,GPR84,CEACAM6,CRISP3,CHI3L1,CHIT1,CXCL1,OLR1,SLC2A3,PDXK,CEACAM1,ARG1,MMP25,PRAM1,S100P,RETN,FCAR,BPI,CLEC4D,HP,PTX3,CYSTM1,QPCT,ELANE,GCA,LTF,CKAP4,MMP8,MMP9,PADI2,KLRC2"
Biological Process	GO:0099500	vesicle fusion to plasma membrane	5.68E-23	43	32.82%	1015	"TARM1,AMPD3,ADGRG3,STBD1,PGLYRP1,CD177,ABCA13,FOLR3,ANXA3,CAMP,CEACAM3,CEACAM8,OLFM4,GPR84,CEACAM6,CRISP3,CHI3L1,CHIT1,CXCL1,OLR1,SLC2A3,PDXK,CEACAM1,ARG1,MMP25,PRAM1,S100P,RETN,FCAR,BPI,CLEC4D,HP,PTX3,CYSTM1,QPCT,ELANE,GCA,LTF,CKAP4,MMP8,MMP9,PADI2,KLRC2"
Cellular Component	GO:0030141	secretory granule	2.80E-25	44	33.59%	958	"TARM1,AMPD3,ADGRG3,STBD1,FSTL3,PGLYRP1,CD177,ABCA13,FOLR3,ANXA3,CAMP,CEACAM3,CEACAM8,OLFM4,GPR84,CEACAM6,CRISP3,CHI3L1,CHIT1,CXCL1,OLR1,SLC2A3,PDXK,CEACAM1,ARG1,MMP25,DEFA3,S100P,RETN,FCAR,BPI,CLEC4D,HP,PTX3,CYSTM1,QPCT,ELANE,GCA,LTF,CKAP4,MMP8,MMP9,PADI2,CA4"
Cellular Component	GO:0099503	secretory vesicle	9.54E-22	44	33.59%	1197	"TARM1,AMPD3,ADGRG3,STBD1,FSTL3,PGLYRP1,CD177,ABCA13,FOLR3,ANXA3,CAMP,CEACAM3,CEACAM8,OLFM4,GPR84,CEACAM6,CRISP3,CHI3L1,CHIT1,CXCL1,OLR1,SLC2A3,PDXK,CEACAM1,ARG1,MMP25,DEFA3,S100P,RETN,FCAR,BPI,CLEC4D,HP,PTX3,CYSTM1,QPCT,ELANE,GCA,LTF,CKAP4,MMP8,MMP9,PADI2,CA4"
Cellular Component	GO:0042581	specific granule	8.45E-38	32	24.43%	160	"TARM1,ADGRG3,PGLYRP1,CD177,FOLR3,ANXA3,CAMP,CEACAM3,CEACAM8,OLFM4,GPR84,CRISP3,CHI3L1,CHIT1,CXCL1,OLR1,SLC2A3,PDXK,CEACAM1,ARG1,MMP25,RETN,FCAR,BPI,CLEC4D,HP,PTX3,QPCT,ELANE,LTF,CKAP4,MMP8"
Cellular Component	GO:0031226	intrinsic component of plasma membrane	7.95E-04	26	19.85%	1910	"GPHN,VIPR1,NRG1,FLT1,ADGRG3,STBD1,TRPA1,CD177,FOLR3,CEACAM8,CEACAM4,GPR84,CEACAM6,TNFRSF10C,LRRC4,IL18RAP,OLR1,SLC2A3,CEACAM1,TGFA,FCAR,KCNJ15,SCN8A,KLRC1,KLRC2,CA4"
Cellular Component	GO:0070820	tertiary granule	9.46E-25	24	18.32%	164	"TARM1,STBD1,PGLYRP1,CD177,FOLR3,CAMP,CEACAM8,OLFM4,GPR84,CRISP3,CHIT1,CXCL1,OLR1,SLC2A3,CEACAM1,FCAR,CLEC4D,HP,PTX3,CYSTM1,QPCT,LTF,MMP8,MMP9"
Cellular Component	GO:0034774	secretory granule lumen	1.88E-16	23	17.56%	332	"AMPD3,PGLYRP1,FOLR3,CAMP,OLFM4,CRISP3,CHI3L1,CHIT1,CXCL1,PDXK,ARG1,DEFA3,S100P,RETN,BPI,HP,PTX3,QPCT,ELANE,GCA,LTF,MMP8,PADI2"
Cellular Component	GO:0060205	cytoplasmic vesicle lumen	2.10E-16	23	17.56%	336	"AMPD3,PGLYRP1,FOLR3,CAMP,OLFM4,CRISP3,CHI3L1,CHIT1,CXCL1,PDXK,ARG1,DEFA3,S100P,RETN,BPI,HP,PTX3,QPCT,ELANE,GCA,LTF,MMP8,PADI2"
Cellular Component	GO:0031983	vesicle lumen	2.10E-16	23	17.56%	338	"AMPD3,PGLYRP1,FOLR3,CAMP,OLFM4,CRISP3,CHI3L1,CHIT1,CXCL1,PDXK,ARG1,DEFA3,S100P,RETN,BPI,HP,PTX3,QPCT,ELANE,GCA,LTF,MMP8,PADI2"
Cellular Component	GO:0030659	cytoplasmic vesicle membrane	5.90E-07	21	16.03%	842	"TARM1,ADGRG3,STBD1,CD177,ABCA13,ANXA3,CEACAM3,CEACAM8,GPR84,CEACAM6,WLS,OLR1,SLC2A3,CEACAM1,TGFA,MMP25,FCAR,CLEC4D,CYSTM1,CKAP4,CA4"
Cellular Component	GO:0012506	vesicle membrane	8.76E-07	21	16.03%	865	"TARM1,ADGRG3,STBD1,CD177,ABCA13,ANXA3,CEACAM3,CEACAM8,GPR84,CEACAM6,WLS,OLR1,SLC2A3,CEACAM1,TGFA,MMP25,FCAR,CLEC4D,CYSTM1,CKAP4,CA4"
Cellular Component	GO:0005887	integral component of plasma membrane	1.77E-02	21	16.03%	1813	"VIPR1,NRG1,FLT1,ADGRG3,STBD1,TRPA1,CEACAM8,CEACAM4,GPR84,CEACAM6,LRRC4,IL18RAP,OLR1,SLC2A3,CEACAM1,TGFA,FCAR,KCNJ15,SCN8A,KLRC1,KLRC2"
Cellular Component	GO:0035580	specific granule lumen	3.26E-24	18	13.74%	62	"PGLYRP1,FOLR3,CAMP,OLFM4,CRISP3,CHI3L1,CHIT1,CXCL1,PDXK,ARG1,RETN,BPI,HP,PTX3,QPCT,ELANE,LTF,MMP8"
Cellular Component	GO:0030667	secretory granule membrane	3.15E-11	18	13.74%	329	"TARM1,ADGRG3,STBD1,CD177,ABCA13,CEACAM3,CEACAM8,GPR84,CEACAM6,OLR1,SLC2A3,CEACAM1,MMP25,FCAR,CLEC4D,CYSTM1,CKAP4,CA4"
Cellular Component	GO:0005764	lysosome	6.06E-05	17	12.98%	772	"ABCA13,LITAF,CEACAM8,OLFM4,CEACAM6,CST7,TLR9,CHIT1,ARSG,ARG1,DEFA3,RETN,BPI,ELANE,GCA,CKAP4,PADI2"
Cellular Component	GO:0000323	lytic vacuole	6.06E-05	17	12.98%	772	"ABCA13,LITAF,CEACAM8,OLFM4,CEACAM6,CST7,TLR9,CHIT1,ARSG,ARG1,DEFA3,RETN,BPI,ELANE,GCA,CKAP4,PADI2"
Cellular Component	GO:0009986	cell surface	4.51E-03	17	12.98%	1131	"NRG1,BTNL8,FOLR3,PPFIA4,CEACAM8,CEACAM4,CEACAM6,TNFRSF10C,CEACAM1,TGFA,MMP25,ELANE,LTF,CKAP4,KLRC1,KLRC2,CA4"
Cellular Component	GO:1904724	tertiary granule lumen	2.78E-16	13	9.92%	55	"PGLYRP1,FOLR3,CAMP,OLFM4,CRISP3,CHIT1,CXCL1,HP,PTX3,QPCT,LTF,MMP8,MMP9"
Cellular Component	GO:0035579	specific granule membrane	2.76E-13	13	9.92%	91	"TARM1,ADGRG3,CD177,CEACAM3,CEACAM8,GPR84,OLR1,SLC2A3,CEACAM1,MMP25,FCAR,CLEC4D,CKAP4"
Cellular Component	GO:0042582	azurophil granule	4.43E-09	12	9.16%	158	"ABCA13,CEACAM8,OLFM4,CEACAM6,ARG1,DEFA3,RETN,BPI,ELANE,GCA,CKAP4,PADI2"
Cellular Component	GO:0005766	primary lysosome	4.43E-09	12	9.16%	158	"ABCA13,CEACAM8,OLFM4,CEACAM6,ARG1,DEFA3,RETN,BPI,ELANE,GCA,CKAP4,PADI2"
Molecular Function	GO:0005509	calcium ion binding	4.74E-02	13	9.92%	815	"PADI4,CLEC6A,GALNT3,CD177,ANXA3,DGKG,S100P,THBS4,FBN2,EFCAB12,GCA,MMP8,PADI2"
Molecular Function	GO:0030246	carbohydrate binding	6.81E-03	10	7.63%	314	"STBD1,CLEC6A,GALNT3,CHI3L1,OLR1,SLC2A3,CLEC4D,PTX3,KLRC1,KLRC2"
Molecular Function	GO:0016810	"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"	4.89E-02	5	3.82%	142	"AMPD3,PADI4,PGLYRP1,ARG1,PADI2"
Molecular Function	GO:0046790	virion binding	6.81E-03	4	3.05%	27	"CEACAM8,CEACAM6,CEACAM1,PTX3"
Molecular Function	GO:0016813	"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"	7.75E-03	3	2.29%	12	"PADI4,ARG1,PADI2"
Molecular Function	GO:0005130	granulocyte colony-stimulating factor receptor binding	1.19E-02	3	2.29%	15	"CEACAM8,CEACAM6,CEACAM1"
Molecular Function	GO:0035325	Toll-like receptor binding	3.59E-02	3	2.29%	29	"CEACAM8,CEACAM6,CEACAM1"
Molecular Function	GO:0031005	filamin binding	3.59E-02	3	2.29%	30	"CEACAM8,CEACAM6,CEACAM1"
Molecular Function	GO:0015125	bile acid transmembrane transporter activity	4.03E-02	3	2.29%	33	"CEACAM8,CEACAM6,CEACAM1"
Molecular Function	GO:0001968	fibronectin binding	4.74E-02	3	2.29%	39	"FSTL3,THBS4,MMP9"
Molecular Function	GO:0062082	HLA-E specific inhibitory MHC class Ib receptor activity	1.76E-02	2	1.53%	4	"KLRC1,KLRC2"
Molecular Function	GO:0062080	inhibitory MHC class Ib receptor activity	1.76E-02	2	1.53%	4	"KLRC1,KLRC2"
Molecular Function	GO:0004668	protein-arginine deiminase activity	2.51E-02	2	1.53%	5	"PADI4,PADI2"
Molecular Function	GO:0004568	chitinase activity	3.28E-02	2	1.53%	6	"CHI3L1,CHIT1"
Molecular Function	GO:0023024	MHC class I protein complex binding	3.59E-02	2	1.53%	7	"KLRC1,KLRC2"
Molecular Function	GO:0008061	chitin binding	4.03E-02	2	1.53%	8	"CHI3L1,CHIT1"
Molecular Function	GO:0005153	interleukin-8 receptor binding	4.15E-02	2	1.53%	9	"CXCL1,CXCL6"
Molecular Function	GO:0032394	MHC class Ib receptor activity	4.15E-02	2	1.53%	9	"KLRC1,KLRC2"
Molecular Function	GO:0004062	aryl sulfotransferase activity	4.74E-02	2	1.53%	10	"SULT1A2,SULT1B1"
Pathway	1269203	Innate Immune System	4.70E-18	46	35.11%	1302	"NRG1, TARM1, AMPD3, ADGRG3, STBD1, CLEC6A, PGLYRP1, CD177, ABCA13, FOLR3, CAMP, CEACAM3, CEACAM8, OLFM4, GPR84, CEACAM6, CRISP3, MUC5B, TLR9, CHI3L1, CHIT1, CXCL1, OLR1, SLC2A3, PDXK, CEACAM1, ARG1, MMP25, DEFA3, S100P, RETN, FCAR, BPI, CLEC4D, HP, PTX3, CYSTM1, QPCT, ELANE, GCA, LTF, CKAP4, MMP8, MMP9, PADI2, KLRC2"
Pathway	1457780	Neutrophil degranulation	2.53E-28	40	30.53%	492	"TARM1, AMPD3, ADGRG3, STBD1, PGLYRP1, CD177, ABCA13, FOLR3, CAMP, CEACAM3, CEACAM8, OLFM4, GPR84, CEACAM6, CRISP3, CHI3L1, CHIT1, CXCL1, OLR1, SLC2A3, PDXK, CEACAM1, ARG1, MMP25, S100P, RETN, FCAR, BPI, CLEC4D, HP, PTX3, CYSTM1, QPCT, ELANE, GCA, LTF, CKAP4, MMP8, MMP9, PADI2"
Pathway	M5885	"Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors"	1.98E-02	16	12.21%	751	"NRG1, CLEC6A, FSTL3, ANXA3, CST7, MUC5B, HTRA4, CXCL1, TGFA, MMP25, S100P, CLEC4D, ELANE, MMP8, MMP9, CXCL6"
Pathway	1457777	Antimicrobial peptides	1.62E-02	6	4.58%	99	"PGLYRP1,CAMP,DEFA3,BPI,ELANE,LTF"
Pathway	1270258	Activation of Matrix Metalloproteinases	1.62E-02	4	3.05%	33	"MMP25,ELANE,MMP8,MMP9"
Pathway	M5885	"Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors"	1.98E-02	16	12.21%	751	"NRG1,CLEC6A,FSTL3,ANXA3,CST7,MUC5B,HTRA4,CXCL1,TGFA,MMP25,S100P,CLEC4D,ELANE,MMP8,MMP9,CXCL6"